[ { "uniprot_canonical_ac": "A0AAA9TS03-1", "uniprot_ac": "A0AAA9TS03", "uniprot_id": "A0AAA9TS03_BOVIN", "mass": { "chemical_mass": 55742.0, "monoisotopic_mass": 55742.0 }, "refseq": {}, "gene_names": [ { "name": "PNKP", "type": "recommended", "evidence": [ { "id": "A0AAA9TS03", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TS03" } ] } ], "protein_names": [ { "name": "Polynucleotide kinase 3'-phosphatase", "type": "synonym", "evidence": [ { "id": "A0AAA9TS03", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TS03/entry#names_and_taxonomy" } ] } ], "function": [], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Bos taurus", "taxid": 9913, "evidence": [ { "database": "UniProtKB", "id": "A0AAA9TS03", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TS03" } ], "common_name": "Bovine", "glygen_name": "Bovine", "reference_species": "Bos taurus [9913]" } ], "gene": [ { "name": "PNKP", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TS03", "locus": { "chromosome": "18", "start_pos": 56210693, "end_pos": 56215660, "strand": "+", "evidence": [ { "database": "Ensembl Gene", "id": "ENSBTAG00000001834", "url": "https://www.ensembl.org/id/ENSBTAG00000001834" } ] } } ], "crossref": [ { "id": "A0AAA9TS03", "url": "https://alphafold.ebi.ac.uk/entry/A0AAA9TS03", "database": "AlphaFoldDB", "categories": [] }, { "id": "ENSBTAG00000001834", "url": "https://bgee.org/?page=gene&gene_id=ENSBTAG00000001834", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "cd01625", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd01625", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "cd22736", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd22736", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "IPR006549", "url": "https://www.ebi.ac.uk/interpro/entry/IPR006549", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR006550", "url": "https://www.ebi.ac.uk/interpro/entry/IPR006550", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR006551", "url": "https://www.ebi.ac.uk/interpro/entry/IPR006551", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR008984", "url": "https://www.ebi.ac.uk/interpro/entry/IPR008984", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR013954", "url": "https://www.ebi.ac.uk/interpro/entry/IPR013954", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR023214", "url": "https://www.ebi.ac.uk/interpro/entry/IPR023214", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR027417", "url": "https://www.ebi.ac.uk/interpro/entry/IPR027417", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR036412", "url": "https://www.ebi.ac.uk/interpro/entry/IPR036412", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR041388", "url": "https://www.ebi.ac.uk/interpro/entry/IPR041388", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "bta:616621", "url": "https://www.genome.jp/dbget-bin/www_bget?bta:616621", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "AADWKWW", "url": "https://omabrowser.org/oma/group/AADWKWW/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "F1N3Q9", "url": "https://www.orthodb.org/?gene=F1N3Q9", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR12083", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR12083", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR12083:SF9", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR12083:SF9", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF08645", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF08645", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF13671", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF13671", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF17913", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF17913", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "R-BTA-5649702", "url": "https://www.reactome.org/PathwayBrowser/#R-BTA-5649702", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "A0AAA9TS03", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TS03", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0AAA9TS03-1", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TS03-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "F1N3Q9", "url": "https://www.uniprot.org/uniprotkb/F1N3Q9", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "F1N3Q9-1", "url": "https://www.uniprot.org/uniprotkb/F1N3Q9-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MAAVAPSCGLKRGVLPSKEGTSHPRIQILTPPLQSSVELVADPETRTVAVKQLGVNPSTAGTQELRPGLKGALGVGDTLYLVNGLHPLTLRWEEALTPESQPDTPPSTPPVTREGEEENVEQQKKRIRKSSPGWETFEKLLVFTAPGVKARGKVAGFDLDGTLITTRSGKVFPTGPSDWRILYLEIPRKLRELAAKGYKLVIFTNQMGIGRGKLRAEEFKAKVEAVVEKLGVPFQVLVATHAGLYRKPVSGMWDHLQEQANEGVPISIGDSVFVGDAAGRPANWAPGRKKKDFSCADRLFALNVGLPFTTPEEFFLKWPATRFELPAFDPRSVARSGPLCLPESSSLLSSDPEVVVAVGFPGAGKSTFLREHLVSAGYVHVNRDTLGSWQRCVTACEAALKQRKPVVIDNTNPDVQSRARYIKCARDAGVPCRCFLFSATVEQARHNNRFREMTDSSHVPVSDIVIYGYRKQFEAPTLAEGFAAVLEIPFRLHVAPQLERLYRQFSEG", "length": 508, "header": "tr|A0AAA9TS03-1|A0AAA9TS03_BOVIN Isoform 1 of Polynucleotide kinase 3'-phosphatase OS=Bos taurus OX=9913 GN=PNKP PE=4 SV=1 CANONICAL=A0AAA9TS03-1" }, "isoforms": [ { "isoform_ac": "A0AAA9TS03-1", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TS03/entry", "sequence": { "sequence": "MAAVAPSCGLKRGVLPSKEGTSHPRIQILTPPLQSSVELVADPETRTVAVKQLGVNPSTAGTQELRPGLKGALGVGDTLYLVNGLHPLTLRWEEALTPESQPDTPPSTPPVTREGEEENVEQQKKRIRKSSPGWETFEKLLVFTAPGVKARGKVAGFDLDGTLITTRSGKVFPTGPSDWRILYLEIPRKLRELAAKGYKLVIFTNQMGIGRGKLRAEEFKAKVEAVVEKLGVPFQVLVATHAGLYRKPVSGMWDHLQEQANEGVPISIGDSVFVGDAAGRPANWAPGRKKKDFSCADRLFALNVGLPFTTPEEFFLKWPATRFELPAFDPRSVARSGPLCLPESSSLLSSDPEVVVAVGFPGAGKSTFLREHLVSAGYVHVNRDTLGSWQRCVTACEAALKQRKPVVIDNTNPDVQSRARYIKCARDAGVPCRCFLFSATVEQARHNNRFREMTDSSHVPVSDIVIYGYRKQFEAPTLAEGFAAVLEIPFRLHVAPQLERLYRQFSEG", "length": 508, "header": "tr|A0AAA9TS03-1|A0AAA9TS03_BOVIN Isoform 1 of Polynucleotide kinase 3'-phosphatase OS=Bos taurus OX=9913 GN=PNKP PE=4 SV=1 CANONICAL=A0AAA9TS03-1" }, "locus": { "chromosome": "18", "start_pos": 56214967, "end_pos": 56210776, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000108048.1", "url": "https://www.ensembl.org/id/ENSBTAT00000108048.1" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000099253.1", "url": "https://www.ensembl.org/id/ENSBTAP00000099253.1" } ] } }, { "isoform_ac": "F1N3Q9-1", "url": "https://www.uniprot.org/uniprotkb/F1N3Q9/entry", "sequence": { "sequence": "MARVETQGRLWLESPAGGAPPIFLPTGGQALVLGRGPLTQVTDRKCSRNQVELVADPETRTVAVKQLGVNPSTAGTQELRPGLKGALGVGDTLYLVNGLHPLTLRWEEALTPESQPDTPPSTPPVTREGEEENVEQQKKRIRKSSPGWETFEKLLVFTAPGVKARGKVAGFDLDGTLITTRSGKVFPTGPSDWRILYLEIPRKLRELAAKGYKLVIFTNQMGIGRGKLRAEEFKAKVEAVVEKLGVPFQVLVATHAGLYRKPVSGMWDHLQEQANEGVPISIGDSVFVGDAAGRPANWAPGRKKKDFSCADRLFALNVGLPFTTPEEFFLKWPATRFELPAFDPRSVARSGPLCLPESSSLLSSDPEVVVAVGFPGAGKSTFLREHLVSAGYVHVNRDTLGSWQRCVTACEAALKQRKPVVIDNTNPDVQSRARYRGPREGPWRAAPGPLPSPPPSSPQGTSSVPGMRACPAAASSSVPPWSRRATTTGSGR", "length": 492, "header": "tr|F1N3Q9-1|F1N3Q9_BOVIN Computationally mapped isoform of Polynucleotide kinase 3'-phosphatase OS=Bos taurus OX=9913 GN=PNKP PE=4 SV=3 CANONICAL=A0AAA9TS03-1" }, "locus": { "chromosome": "18", "start_pos": 56215654, "end_pos": 56211029, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000002397.7", "url": "https://www.ensembl.org/id/ENSBTAT00000002397.7" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000002397.6", "url": "https://www.ensembl.org/id/ENSBTAP00000002397.6" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [ { "id": "bta:616621", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?bta:616621", "resource": "KEGG Pathway" }, { "id": "R-BTA-5649702", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-BTA-5649702", "resource": "Reactome", "description": "APEX1-Independent Resolution of AP Sites via the Single Nucleotide Replacement Pathway" } ], "orthologs": [ { "uniprot_canonical_ac": "A0A0G2JUH4-1", "protein_name": "Bifunctional polynucleotide phosphatase/kinase", "gene_name": "Pnkp", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MSELGSRGRLWLQSPTGGPPPIFLPSDGQALVLGRGPLTQVMDRKCSRNQVELIADPETRTVAVKQLGVNPSTVGVQELKPGVSGSLSVGDVLYLVNGLYPLTLRWEEISTPGSPPDTPPGNPVDPEEGKDTEPQKKRMRKSSPGWESFKQLLVFTASGVKPRGKVAAFDLDGTLITTRSGKVFPTSPSDWRILYPEIPKKLQELAAEGYKLVILTNQMGIGRGKLPAEVFKAKVEAVLEKLGVPFQVLVATHAGLNRKPVSGMWDHLQEKGNEGIPISIGDSVFVGGSRAPSQLGPREEEKGFLLCRPPGKPGFALNVGLPFATPEEFFLKWPAARFELPAFDPRTISSAGPLYLPESSFLLSPNPEVVVAVGFPGAGKSTFIQKHLVSAGYVHVNRDTLGSWQRCVNSCQAALRQGKQVVIDNTNPDIQSRARYIQCAKDAGVPCRCFSFCATIEQARHNNRFREMTDPSHAPVSDMVMFSYRKQFEPPTLAEGFLEILQVPFRLQEHLDPALQRLYCQFSEG", "length": 525 }, "evidence": [ { "id": "A0AAA9TS03", "url": "https://omabrowser.org/oma/group/A0AAA9TS03/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "A0A0R4IRS4-1", "protein_name": "Bifunctional polynucleotide phosphatase/kinase", "gene_name": "pnkp", "tax_id": 7955, "organism": "Danio rerio", "sequence": { "sequence": "MEMQCTLVSVDGDRVVLPDGRALMFGRGPESRISDKKCSRHQVKLVADYAKQEVLVTQLGPNPSSLDGQCLGRGESGCLTTGQTLYLVNESYPFTVEFAFHCGIQLSSSPQKKEKITNESKQRQKSSKESSGSLKRNIHDYFSKSPKKAAKRPYSPEDDVPQPKRGREDEDNEDEGTSAEQKLQQLQAFAQSESDNFKSSNPSSTCSQSHWQQIGSLMLFTAAGVTASSKIAGFDIDGCIITTKSGKVFPTGPDDWRILYPEIQPKLASLLKKGYKVVFFTNQMGISRGKLRPEVFKSKAEDILQTLQLPIQVFVSTAPGIYRKPVIGMWEHLCEKANSGVMVDVSESFYVGDAAGRPANWAPGKKKKDFSCSDRLFALNIGLQFYTPEEYFLGWKPATFSFPEFDPRKLDSKARLYDPPDASLTSTKQEIIVAVGFPGAGKSTFFQTHIIPKGYAYVNRDTMGSWQHCVSACERALKEGKSVAVDNTNPDLESRKRYIDVAQSAGVSCRCFNFTASLDQAKHNNRFREMVPSATKHVPVNDMVIHSYKKKFVVPSLSEGFSEVLQIHFVPSFSDKRSEFLFKQFSEG", "length": 588 }, "evidence": [ { "id": "A0AAA9TS03", "url": "https://omabrowser.org/oma/group/A0AAA9TS03/", "database": "OMA" } ], "glygen_name": "Zebrafish", "common_name": "Zebrafish" }, { "uniprot_canonical_ac": "G3I715-1", "protein_name": "Bifunctional polynucleotide phosphatase/kinase", "gene_name": "Pnkp", "tax_id": 10029, "organism": "Cricetulus griseus", "sequence": { "sequence": "MSQLGSRGRLWLQSPTEGPPPIFLPSDGQALVLGRGPLTQVTDRKCSRNQVELIADPETRTVAVKQLGVNPSTVGVQELKPGLSGSLSLGDSLYLVNGLYPLTLRWEEISTTGSQPDTPPGTPPSDPVDREDAEPQKKRRRKSSPGWESLKKLLVFTASGVESRGKVAAFDLDGTLITTRSGKVFPTSPSDWRILYPGIPKKLQELDAEGYKLVIFTNQMGIGRGKLPAEVFKAKVEAVLEKLGVPFQVLVATHAGLNRKPVSGMWDHLQEQANEGMPISIGDSIFVGDAAGRPANWAPGKKKDFSCADRLFALNIGLPFATPEEFFLKWPAAGFELPAFDPRTISSAGPLYIPESSVLLSPNPEVVVTVGFPGAGKSTFVQEHLVSAGYVHVNRDTLGSWQRCVSSCQAALRQGKRVVIDNTNPDVPSRARYIQCARDAGVPCRCFNFCATLEQARHNNRFREMTDPSHAPVSDMVMFSYRKQFELPMLTEGFQEILQIPFQLRTHPDPALQRLYCQFLEG", "length": 522 }, "evidence": [ { "id": "A0AAA9TS03", "url": "https://omabrowser.org/oma/group/A0AAA9TS03/", "database": "OMA" } ], "glygen_name": "Hamster", "common_name": "Chinese hamster" }, { "uniprot_canonical_ac": "Q96T60-1", "protein_name": "Bifunctional polynucleotide phosphatase/kinase", "gene_name": "PNKP", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MGEVEAPGRLWLESPPGGAPPIFLPSDGQALVLGRGPLTQVTDRKCSRTQVELVADPETRTVAVKQLGVNPSTTGTQELKPGLEGSLGVGDTLYLVNGLHPLTLRWEETRTPESQPDTPPGTPLVSQDEKRDAELPKKRMRKSNPGWENLEKLLVFTAAGVKPQGKVAGFDLDGTLITTRSGKVFPTGPSDWRILYPEIPRKLRELEAEGYKLVIFTNQMSIGRGKLPAEEFKAKVEAVVEKLGVPFQVLVATHAGLYRKPVTGMWDHLQEQANDGTPISIGDSIFVGDAAGRPANWAPGRKKKDFSCADRLFALNLGLPFATPEEFFLKWPAAGFELPAFDPRTVSRSGPLCLPESRALLSASPEVVVAVGFPGAGKSTFLKKHLVSAGYVHVNRDTLGSWQRCVTTCETALKQGKRVAIDNTNPDAASRARYVQCARAAGVPCRCFLFTATLEQARHNNRFREMTDSSHIPVSDMVMYGYRKQFEAPTLAEGFSAILEIPFRLWVEPRLGRLYCQFSEG", "length": 521 }, "evidence": [ { "id": "A0AAA9TS03", "url": "https://omabrowser.org/oma/group/A0AAA9TS03/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "Q9JLV6-1", "protein_name": "Bifunctional polynucleotide phosphatase/kinase", "gene_name": "Pnkp", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MSQLGSRGRLWLQSPTGGPPPIFLPSDGQALVLGRGPLTQVTDRKCSRNQVELIADPESRTVAVKQLGVNPSTVGVHELKPGLSGSLSLGDVLYLVNGLYPLTLRWEELSTSGSQPDAPPDTPGDPEEGEDTEPQKKRVRKSSLGWESLKKLLVFTASGVKPQGKVAAFDLDGTLITTRSGKVFPTSPSDWRILYPEIPKKLQELAAEGYKLVIFTNQMGIGRGKLPAEVFKGKVEAVLEKLGVPFQVLVATHAGLNRKPVSGMWDHLQEQANEGIPISVEDSVFVGDAAGRLANWAPGRKKKDFSCADRLFALNVGLPFATPEEFFLKWPAARFELPAFDPRTISSAGPLYLPESSSLLSPNPEVVVAVGFPGAGKSTFIQEHLVSAGYVHVNRDTLGSWQRCVSSCQAALRQGKRVVIDNTNPDVPSRARYIQCAKDAGVPCRCFNFCATIEQARHNNRFREMTDPSHAPVSDMVMFSYRKQFEPPTLAEGFLEILEIPFRLQEHLDPALQRLYRQFSEG", "length": 522 }, "evidence": [ { "id": "A0AAA9TS03", "url": "https://omabrowser.org/oma/group/A0AAA9TS03/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q9VHS0-1", "protein_name": "3.1.3.32", "gene_name": "PNKP", "tax_id": 7227, "organism": "Drosophila melanogaster", "sequence": { "sequence": "MSMAKYLNRSVGKAGKDVAARICTLKPTEPEHHSIHLTAGENFVGRSRETGIRDSKCSKRQIQLQVDLKKAVVSLKVLGVNPCGVNGLMLMQNGERELKHGDLVEIVYGRHQFEVVFNPPPEYDKEKAEPLSTTLSPSEKSERWDSSGNGKLVIFTSVGVKGSEKIAGYDMDGTIIKTKSGLVFPKNTDDWQIIFPEVPEKLKNLHKDGFKICLFTNQGGIARGKINLDDFKVKIKHIVAKLGVPIQVFIAIGDGFYRKPLTGMWQHLKSEMNDGVEIQEDRCFFVGDAAGRPETGKGATKRRKDHSLVDRLFAANVGISFYTPEVHFLGKQVEQWNKPDFEPTSVQDQVSLLDPDDLTLDDHPCEMVIMVGLPGSGKSHFCSSFFQPRGYKIVNADTLGSTQNCLTACKRFLDSGQSCVVDNTNVDAASRKKFLQLASEKMIPCRCLVMNVPVAQVKHNIAFRELSDSARTKIKDMVFNMMKKKYQEPALDEGFISIHKVNFKPNFADEKQEKLYKMYLVEK", "length": 523 }, "evidence": [ { "id": "A0AAA9TS03", "url": "https://omabrowser.org/oma/group/A0AAA9TS03/", "database": "OMA" } ], "glygen_name": "Fruit fly", "common_name": "Fruit fly" } ], "go_annotation": { "categories": [ { "name": "Molecular Function", "total": 2, "go_terms": [ { "name": "ATP-dependent polydeoxyribonucleotide 5'-hydroxyl-kinase activity", "id": "GO:0046404", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0046404", "evidence": [ { "database": "UniProtKB", "id": "A0AAA9TS03", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TS03" } ], "pmid": "" }, { "name": "polynucleotide 3'-phosphatase activity", "id": "GO:0046403", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0046403", "evidence": [ { "database": "UniProtKB", "id": "A0AAA9TS03", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TS03" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 4, "go_terms": [ { "name": "positive regulation of double-strand break repair via nonhomologous end joining", "id": "GO:2001034", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:2001034", "evidence": [ { "database": "UniProtKB", "id": "A0AAA9TS03", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TS03" } ], "pmid": "" }, { "name": "response to oxidative stress", "id": "GO:0006979", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006979", "evidence": [ { "database": "UniProtKB", "id": "A0AAA9TS03", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TS03" } ], "pmid": "" }, { "name": "double-strand break repair via nonhomologous end joining", "id": "GO:0006303", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006303", "evidence": [ { "database": "UniProtKB", "id": "A0AAA9TS03", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TS03" } ], "pmid": "" }, { "name": "DNA repair", "id": "GO:0006281", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006281", "evidence": [ { "database": "UniProtKB", "id": "A0AAA9TS03", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TS03" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 4, "go_terms": [ { "name": "nucleoplasm", "id": "GO:0005654", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005654", "evidence": [ { "database": "UniProtKB", "id": "A0AAA9TS03", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TS03" } ], "pmid": "" }, { "name": "nucleolus", "id": "GO:0005730", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005730", "evidence": [ { "database": "UniProtKB", "id": "A0AAA9TS03", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TS03" } ], "pmid": "" }, { "name": "site of double-strand break", "id": "GO:0035861", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0035861", "evidence": [ { "database": "UniProtKB", "id": "A0AAA9TS03", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TS03" } ], "pmid": "" }, { "name": "nucleus", "id": "GO:0005634", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005634", "evidence": [ { "database": "UniProtKB", "id": "A0AAA9TS03", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TS03" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A0AAA9TS03", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TS03" }, { "id": "PF17913", "database": "Pfam", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF17913" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "PNK FHA", "eco_id": "ECO_0000259", "start_pos": 35, "end_pos": 65, "start_aa": "Ser", "end_aa": "Leu", "glycosite_overlap": [] } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" }, { "name": "homologset.oma", "label": "OMA Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ], "tool_support": { "graph_view": "yes" } }, { "uniprot_canonical_ac": "A0AAA9TRB8-1", "uniprot_ac": "A0AAA9TRB8", "uniprot_id": "A0AAA9TRB8_BOVIN", "mass": { "chemical_mass": 99793.0, "monoisotopic_mass": 99793.0 }, "refseq": {}, "gene_names": [ { "name": "OSBPL5", "type": "recommended", "evidence": [ { "id": "A0AAA9TRB8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TRB8" } ] } ], "protein_names": [ { "name": "Oxysterol-binding protein", "type": "recommended", "evidence": [ { "id": "A0AAA9TRB8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TRB8/entry#names_and_taxonomy" } ] } ], "function": [ { "annotation": "Lipid transporter involved in lipid countertransport between the endoplasmic reticulum and the plasma membrane: specifically exchanges phosphatidylserine with phosphatidylinositol 4-phosphate (PI4P), delivering phosphatidylserine to the plasma membrane in exchange for PI4P, which is degraded by the SAC1/SACM1L phosphatase in the endoplasmic reticulum. Binds phosphatidylserine and PI4P in a mutually exclusive manner. May cooperate with NPC1 to mediate the exit of cholesterol from endosomes/lysosomes. Binds 25-hydroxycholesterol and cholesterol.", "evidence": [ { "database": "UniProtKB", "id": "A0A3Q1LWY5", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1LWY5#function" }, { "database": "UniProtKB", "id": "ARBA00056710", "url": "https://www.uniprot.org/uniprotkb/ARBA00056710#function" }, { "database": "UniProtKB", "id": "E1BC89", "url": "https://www.uniprot.org/uniprotkb/E1BC89#function" }, { "database": "UniProtKB", "id": "A0AAA9TD96", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TD96#function" }, { "database": "UniProtKB", "id": "A0AAA9TRB8", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TRB8#function" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Bos taurus", "taxid": 9913, "evidence": [ { "database": "UniProtKB", "id": "A0AAA9TRB8", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TRB8" } ], "common_name": "Bovine", "glygen_name": "Bovine", "reference_species": "Bos taurus [9913]" } ], "gene": [ { "name": "OSBPL5", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TRB8", "locus": { "chromosome": "29", "start_pos": 48518568, "end_pos": 48450135, "strand": "-", "evidence": [ { "database": "Ensembl Gene", "id": "ENSBTAG00000001077", "url": "https://www.ensembl.org/id/ENSBTAG00000001077" } ] } } ], "crossref": [ { "id": "A0AAA9TRB8", "url": "https://alphafold.ebi.ac.uk/entry/A0AAA9TRB8", "database": "AlphaFoldDB", "categories": [] }, { "id": "ENSBTAG00000001077", "url": "https://bgee.org/?page=gene&gene_id=ENSBTAG00000001077", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "cd13286", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd13286", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "532690", "url": "https://www.ncbi.nlm.nih.gov/gene/532690", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR000648", "url": "https://www.ebi.ac.uk/interpro/entry/IPR000648", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR001849", "url": "https://www.ebi.ac.uk/interpro/entry/IPR001849", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR011993", "url": "https://www.ebi.ac.uk/interpro/entry/IPR011993", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR018494", "url": "https://www.ebi.ac.uk/interpro/entry/IPR018494", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR037239", "url": "https://www.ebi.ac.uk/interpro/entry/IPR037239", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "A0A3Q1LWY5", "url": "https://www.orthodb.org/?gene=A0A3Q1LWY5", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "E1BC89", "url": "https://www.orthodb.org/?gene=E1BC89", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR10972", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR10972", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR10972:SF213", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR10972:SF213", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00169", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00169", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF01237", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF01237", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "R-BTA-1482801", "url": "https://www.reactome.org/PathwayBrowser/#R-BTA-1482801", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "A0A3Q1LWY5", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1LWY5", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A3Q1LWY5-1", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1LWY5-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0AAA9SC53", "url": "https://www.uniprot.org/uniprotkb/A0AAA9SC53", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0AAA9SC53-1", "url": "https://www.uniprot.org/uniprotkb/A0AAA9SC53-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0AAA9TD96", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TD96", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0AAA9TD96-1", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TD96-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0AAA9TRB8", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TRB8", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0AAA9TRB8-1", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TRB8-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "E1BC89", "url": "https://www.uniprot.org/uniprotkb/E1BC89", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "E1BC89-1", "url": "https://www.uniprot.org/uniprotkb/E1BC89-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MIFSSVNRADVHRLALALLKKPPCAHAMKEEAFLRRRFSLCPPSSTPQKLSRNLLVGGEHEVDVGPGKDMEPHGPSPTRDEGPPTPGSATKVPPAEYRLCNGSDRECVSPTAKAQKESYRQEKKRATRQLLSALTDPSVVIMADSLKIRGTLKSWTKLWCVLKPGVLLIYKTPKVGQWVGTVLLHCCELIERPSKKDGFCFKLFHPLDQSVWAVKGPKGESVGSITQPLPSSYLIFRAASESDGRCWLDALELALRCSSLLRLSTCKQGRDGEPGSSPDGSPSSLCGLPASGAIHDQDLFPLNGSSLENDAFSDKSERENAEESDNETHDHSRKTESGSDQSEAPVGPGHRGTTYVVQDHEELGERGEASQVETVSEENKSLVWVLLKQLRPGMDLSRVALPTFVLEPRSFLNKLSDYYCHADLLSRAALEEDAYSRIKLVLRWYLSGFYKKPKGIKKPYNPILGETFRCCWFHPQTNSHTFYIAEQVSHHPPVSAFHVSNRKDGFCISGSITAKSRFYGNSLSALLDGKATLTFLNRAEDYSLTMPYAHCKGILYGTMTMELGGRVTIECEKNSLQAELEFKLKPFFGGSTSINQISGKITSGEEVLARLTGHWDREVFIKEEGRGGPELFWNPSEEVRRQRLKRYTVLLEEQTELESERLWQHVTRAISEGDQHKATQEKFSLEEAQRQRARERQQNLVPWTPQLFHLDPATQEWRYRYENHSPWDPLKDIAQFEQDGVLHTLQRETMAGQTAFLGSPGPRHQGSTPNPRLRKPSDQPSGHSQVTESSGSTPESCPELSDEEEEDGDIVPGCESPCPRCGKEARRLQVLHEAILSIREAQQELHRHLSAMLSSTARARQAPAPGPLHSPRSWFLLCVFLACQLLINYILK", "length": 892, "header": "tr|A0AAA9TRB8-1|A0AAA9TRB8_BOVIN Isoform 1 of Oxysterol-binding protein OS=Bos taurus OX=9913 GN=OSBPL5 PE=3 SV=1 CANONICAL=A0AAA9TRB8-1" }, "isoforms": [ { "isoform_ac": "A0A3Q1LWY5-1", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1LWY5/entry", "sequence": { "sequence": "MRSMWVQAEYRLCNGSDRECVSPTAKVSKKEALKAQKESYRQEKKRATRQLLSALTDPSVVIMADSLKIRGTLKSWTKLWCVLKPGVLLIYKTPKVGQWVGTVLLHCCELIERPSKKDGFCFKLFHPLDQSVWAVKGPKGESVGSITQPLPSSYLIFRAASESDGRCWLDALELALRCSSLLRLSTCKQGRDGEPGSSPDGSPSSLCGLPASGAIHDQDLFPLNGSSLENDAFSDKSERENAEESDNETHDHSRKTESGSDQSEAPVGPGHRGTTYVVQDHEELGERGEASQVETVSEENKSLVWVLLKQLRPGMDLSRVALPTFVLEPRSFLNKLSDYYCHADLLSRAALEEDAYSRIKLVLRWYLSGFYKKPKGIKKPYNPILGETFRCCWFHPQTNSHTFYIAEQVSHHPPVSAFHVSNRKDGFCISGSITAKSRFYGNSLSALLDGKATLTFLNRAEDYSLTMPYAHCKGILYGTMTMELGGRVTIECEKNSLQAELEFKLKPFFGGSTSINQISGKITSGEEVLARLTGHWDREVFIKEEGRGGPELFWNPSEEVRRQRLKRYTVLLEEQTELESERLWQHVTRAISEGDQHKATQEKFSLEEAQRQRARERQQNLVPWTPQLFHLDPATQEWRYRYENHSPWDPLKDIAQFEQDGVLHTLQRETMAGQTAFLGSPGPRHQGSTPNPRLRKPSDQPSGHSQVTESSGSTPESCPELSDEEEEDGDIVPGCESPCPRCGKEARRLQVLHEAILSIREAQQELHRHLSAMLSSTARARQAPAPGPLHSPRSWFLLCVFLACQLLINYILK", "length": 813, "header": "tr|A0A3Q1LWY5-1|A0A3Q1LWY5_BOVIN Computationally mapped isoform of Oxysterol-binding protein OS=Bos taurus OX=9913 GN=OSBPL5 PE=3 SV=2 CANONICAL=A0AAA9TRB8-1" }, "locus": { "chromosome": "29", "start_pos": 48517564, "end_pos": 48485360, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000073265.3", "url": "https://www.ensembl.org/id/ENSBTAT00000073265.3" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000061970.2", "url": "https://www.ensembl.org/id/ENSBTAP00000061970.2" } ] } }, { "isoform_ac": "A0AAA9SC53-1", "url": "https://www.uniprot.org/uniprotkb/A0AAA9SC53/entry", "sequence": { "sequence": "MKEEAFLRRRFSLCPPSSTPQKLSRNLLVGGEHEVDVGPGKDMEPHGPSPTRDEGPPTPGSATKVPPAEYRLCNGSDRECVSPTAKVSKKEALKAQKESYRQEKKRATRQLLSALTDPSVVIMADSLKGPKGESVGSITQPLPSSYLIFRAASESDGRCWLDALELALRCSSLLRLSTCKQGRDGEPGSSPDGSPSSLCGLPASGAIHDQDLFPLNGSSLENDAFSDKSERENAEESDNETHDHSRKTESGSDQSEAPVGPGHRGTTYVVQDHEELGERGEASQVETVSEENKSLVWVLLKQLRPGMDLSRVALPTFVLEPRSFLNKLSDYYCHADLLSRAALEEDAYSRIKLVLRWYLSGFYKKPKGIKKPYNPILGETFRCCWFHPQTNSHTFYIAEQVSHHPPVSAFHVSNRKDGFCISGSITAKSRFYGNSLSALLDGKATLTFLNRAEDYSLTMPYAHCKGILYGTMTMELGGRVTIECEKNSLQAELEFKLKPFFGGSTSINQISGKITSGEEVLARLTGHWDREVFIKEEGRGGPELFWNPSEEVRRQRLKRYTVLLEEQTELESERLWQHVTRAISEGDQHKATQEKFSLEEAQRQRARERQQNLVPWTPQLFHLDPATQEWRYRYENHSPWDPLKDIAQFEQDGVLHTLQRETMAGQTAFLGSPGPRHQGSTPNPRLRKPSDQPSGHSQVTESSGSTPESCPELSDEEEEDGDIVPGCESPCPRCGKEARRLQVLHEAILSIREAQQELHRHLSAMLSSTARARQAPAPGPLHSPRSWFLLCVFLACQLLINYILK", "length": 805, "header": "tr|A0AAA9SC53-1|A0AAA9TRB8_BOVIN Computationally mapped isoform of Oxysterol-binding protein OS=Bos taurus OX=9913 GN=OSBPL5 PE=3 SV=1 CANONICAL=A0AAA9TRB8-1" }, "locus": { "chromosome": "29", "start_pos": 48517564, "end_pos": 48485263, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000117941.2", "url": "https://www.ensembl.org/id/ENSBTAT00000117941.2" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000083691.1", "url": "https://www.ensembl.org/id/ENSBTAP00000083691.1" } ] } }, { "isoform_ac": "A0AAA9TD96-1", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TD96/entry", "sequence": { "sequence": "MKEEAFLRRRFSLCPPSSTPQKLSRNLLVGGEHEVDVGPGKDMEPHGPSPTRDEGPPTPGSATKVPPAEYRLCNGSDRECVSPTAKVSKKEALKAQKESYRQEKKRATRQLLSALTDPSVVIMADSLKIRGTLKSWTKLWCVLKPGVLLIYKTPKVGQWVGTVLLHCCELIERPSKKDGFCFKLFHPLDQSVWAVKGPKGESVGSITQPLPSSYLIFRAASESDGRCWLDALELALRCSSLLRLSTCKQGRDGEPGSSPDGSPSSLCGLPASGAIHDQDLFPLNGSSLENDAFSDKSERENAEESDNETHDHSRKTESGSDQSEAPVGPGHRGTTYVVQDHEELGERGEASQVETVSEENKSLVWVLLKQLRPGMDLSRVALPTFVLEPRSFLNKLSDYYCHADLLSRAALEEDAYSRIKLVLRWYLSGFYKKPKGIKKPYNPILGETFRCCWFHPQTNSHTFYIAEQVSHHPPVSAFHVSNRKDGFCISGSITAKSRFYGNSLSALLDGKATLTFLNRAEDYSLTMPYAHCKGILYGTMTMELGGRVTIECEKNSLQAELEFKLKPFFGGSTSINQISGKITSGEEVLARLTGHWDREVFIKEEGRGGPELFWNPSEEVRRQRLKRYTVLLEEQTELESERLWQHVTRAISEGDQHKATQEKFSLEEAQRQRARERQQNLVPWTPQLFHLDPATQEWRYRYENHSPWDPLKDIAQFEQDGVLHTLQRETMAGQTAFLGSPGPRHQVRTTPGPAWAPPPPPHTQLTWPSSSGSPSHSDPHTSQQGLPWCPPGSLFPTQQGAKTPGLAGHAVPGTPRCSGHCAGVHWPCPIAPQNRPPWCRPGGIPLYR", "length": 848, "header": "tr|A0AAA9TD96-1|A0AAA9TRB8_BOVIN Computationally mapped isoform of Oxysterol-binding protein OS=Bos taurus OX=9913 GN=OSBPL5 PE=3 SV=1 CANONICAL=A0AAA9TRB8-1" }, "locus": { "chromosome": "29", "start_pos": 48514490, "end_pos": 48485263, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000130655.2", "url": "https://www.ensembl.org/id/ENSBTAT00000130655.2" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000096089.1", "url": "https://www.ensembl.org/id/ENSBTAP00000096089.1" } ] } }, { "isoform_ac": "A0AAA9TRB8-1", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TRB8/entry", "sequence": { "sequence": "MIFSSVNRADVHRLALALLKKPPCAHAMKEEAFLRRRFSLCPPSSTPQKLSRNLLVGGEHEVDVGPGKDMEPHGPSPTRDEGPPTPGSATKVPPAEYRLCNGSDRECVSPTAKAQKESYRQEKKRATRQLLSALTDPSVVIMADSLKIRGTLKSWTKLWCVLKPGVLLIYKTPKVGQWVGTVLLHCCELIERPSKKDGFCFKLFHPLDQSVWAVKGPKGESVGSITQPLPSSYLIFRAASESDGRCWLDALELALRCSSLLRLSTCKQGRDGEPGSSPDGSPSSLCGLPASGAIHDQDLFPLNGSSLENDAFSDKSERENAEESDNETHDHSRKTESGSDQSEAPVGPGHRGTTYVVQDHEELGERGEASQVETVSEENKSLVWVLLKQLRPGMDLSRVALPTFVLEPRSFLNKLSDYYCHADLLSRAALEEDAYSRIKLVLRWYLSGFYKKPKGIKKPYNPILGETFRCCWFHPQTNSHTFYIAEQVSHHPPVSAFHVSNRKDGFCISGSITAKSRFYGNSLSALLDGKATLTFLNRAEDYSLTMPYAHCKGILYGTMTMELGGRVTIECEKNSLQAELEFKLKPFFGGSTSINQISGKITSGEEVLARLTGHWDREVFIKEEGRGGPELFWNPSEEVRRQRLKRYTVLLEEQTELESERLWQHVTRAISEGDQHKATQEKFSLEEAQRQRARERQQNLVPWTPQLFHLDPATQEWRYRYENHSPWDPLKDIAQFEQDGVLHTLQRETMAGQTAFLGSPGPRHQGSTPNPRLRKPSDQPSGHSQVTESSGSTPESCPELSDEEEEDGDIVPGCESPCPRCGKEARRLQVLHEAILSIREAQQELHRHLSAMLSSTARARQAPAPGPLHSPRSWFLLCVFLACQLLINYILK", "length": 892, "header": "tr|A0AAA9TRB8-1|A0AAA9TRB8_BOVIN Isoform 1 of Oxysterol-binding protein OS=Bos taurus OX=9913 GN=OSBPL5 PE=3 SV=1 CANONICAL=A0AAA9TRB8-1" }, "locus": { "chromosome": "29", "start_pos": 48517564, "end_pos": 48484394, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000124021.2", "url": "https://www.ensembl.org/id/ENSBTAT00000124021.2" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000100908.1", "url": "https://www.ensembl.org/id/ENSBTAP00000100908.1" } ] } }, { "isoform_ac": "E1BC89-1", "url": "https://www.uniprot.org/uniprotkb/E1BC89/entry", "sequence": { "sequence": 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], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [ 85 ], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 101, "end_pos": 103 }, { "start_pos": 303, "end_pos": 305 }, { "start_pos": 326, "end_pos": 328 }, { "start_pos": 379, "end_pos": 381 }, { "start_pos": 723, "end_pos": 725 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 1 }, { "field": "total_sites", "count": 1 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 1 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "exact_sites", "count": 1 }, { "field": "exact_o_linked_sites", "count": 1 }, { "field": "fuzzy_sites", "count": 0 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", 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"MNGEADCPTDLEMAAPKGQDRWSQEDMLTLLECMKNNIPSNDSSKFKTTESHMDWEKVAFKDFSGDMCKLKWVEISNEVRKFRTLTELILDAQEHVKNPYKGKKLKKHPDFPKKPLTPYFRFFMEKRAKYAKLHPEMSNLDLTKILSKKYKELPEKKKMKYIQDFQREKQEFERNLARFREDHPDLIQNAKKSDIPEKPKTPQQLWYTHEKKVYLKVRPDEIMRDYIQKHPELNISEEGITKSTLTKAERQLKDKFDGRPTKPPPNSYSLYCAELMANMKDVPSTERMVLCSQQWKLLSQKEKDAYHKKCDQKKKDYEVDLLRFLESLPEEEQQRVLGEEKMLNINKKQATSPASKKPSQEAGKGGSEKPKRPVSAMFIFSEEKRRQLQEERPELSESELTRLLARMWNDLSEKKKAKYKAREAALKAQSERKPGKLPESPKRAEEIWQQSVIGDYLARFKNDREKALKAMEMTWNNMEKKEKLMWIKKAAEDQKRYERELSERRAPPAAANSSKKMKFQGEPKKPPMNGYQKFSQELLSNGQLNHLPLKERMVEIGSRWHRISQSQKEHYKKQAEEQQKQYKVNLDLWVKSLSPQERAAYKEYISNKRKNMTKLRGPNPKSSRTALQSKSESEDDDEEDEDEDEEDDEEEDDENGDSSEDGGDSSESSSEDESEDGDENEEDDEDEDDDEDDDEDEDNESEGSSSSSSSSGDSSDSDSN", "length": 720, "header": "tr|A0AAA9TQ73-1|A0AAA9TQ73_BOVIN Isoform 1 of Nucleolar transcription factor 1 OS=Bos taurus OX=9913 GN=UBTF PE=4 SV=1 CANONICAL=A0AAA9TQ73-1" }, "isoforms": [ { "isoform_ac": "A0AAA9TQ73-1", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TQ73/entry", "sequence": { "sequence": "MNGEADCPTDLEMAAPKGQDRWSQEDMLTLLECMKNNIPSNDSSKFKTTESHMDWEKVAFKDFSGDMCKLKWVEISNEVRKFRTLTELILDAQEHVKNPYKGKKLKKHPDFPKKPLTPYFRFFMEKRAKYAKLHPEMSNLDLTKILSKKYKELPEKKKMKYIQDFQREKQEFERNLARFREDHPDLIQNAKKSDIPEKPKTPQQLWYTHEKKVYLKVRPDEIMRDYIQKHPELNISEEGITKSTLTKAERQLKDKFDGRPTKPPPNSYSLYCAELMANMKDVPSTERMVLCSQQWKLLSQKEKDAYHKKCDQKKKDYEVDLLRFLESLPEEEQQRVLGEEKMLNINKKQATSPASKKPSQEAGKGGSEKPKRPVSAMFIFSEEKRRQLQEERPELSESELTRLLARMWNDLSEKKKAKYKAREAALKAQSERKPGKLPESPKRAEEIWQQSVIGDYLARFKNDREKALKAMEMTWNNMEKKEKLMWIKKAAEDQKRYERELSERRAPPAAANSSKKMKFQGEPKKPPMNGYQKFSQELLSNGQLNHLPLKERMVEIGSRWHRISQSQKEHYKKQAEEQQKQYKVNLDLWVKSLSPQERAAYKEYISNKRKNMTKLRGPNPKSSRTALQSKSESEDDDEEDEDEDEEDDEEEDDENGDSSEDGGDSSESSSEDESEDGDENEEDDEDEDDDEDDDEDEDNESEGSSSSSSSSGDSSDSDSN", "length": 720, "header": "tr|A0AAA9TQ73-1|A0AAA9TQ73_BOVIN Isoform 1 of Nucleolar transcription factor 1 OS=Bos taurus OX=9913 GN=UBTF PE=4 SV=1 CANONICAL=A0AAA9TQ73-1" }, "locus": { "chromosome": "19", "start_pos": 44035192, "end_pos": 44024341, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000131568.1", "url": "https://www.ensembl.org/id/ENSBTAT00000131568.1" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000099437.1", "url": "https://www.ensembl.org/id/ENSBTAP00000099437.1" } ] } }, { "isoform_ac": "F1MCZ7-1", "url": "https://www.uniprot.org/uniprotkb/F1MCZ7/entry", "sequence": { "sequence": "MNGEADCPTDLEMAAPKGQDRWSQEDMLTLLECMKNNIPSNDSSKFKTTESHMDWEKVAFKDFSGDMCKLKWVEISNEVRKFRTLTELILDAQEHVKNPYKGKKLKKHPDFPKKPLTPYFRFFMEKRAKYAKLHPEMSNLDLTKILSKKYKELPEKKKMKYIQDFQREKQEFERNLARFREDHPDLIQNAKKSDIPEKPKTPQQLWYTHEKKVYLKVRPDATTKEVKDSLGKQWSQLSDKKRLKWIHKALEQRKEYEEIMRDYIQKHPELNISEEGITKSTLTKAERQLKDKFDGRPTKPPPNSYSLYCAELMANMKDVPSTERMVLCSQQWKLLSQKEKDAYHKKCDQKKKDYEVDLLRFLESLPEEEQQRVLGEEKMLNINKKQATSPASKKPSQEAGKGGSEKPKRPVSAMFIFSEEKRRQLQEERPELSESELTRLLARMWNDLSEKKKAKYKAREAALKAQSERKPGKLPESPKRAEEIWQQSVIGDYLARFKNDREKALKAMEMTWNNMEKKEKLMWIKKAAEDQKRYERELSERRAPPAAANSSKKMKFQGEPKKPPMNGYQKFSQELLSNGQLNHLPLKERMVEIGSRWHRISQSQKEHYKKQAEEQQKQYKVNLDLWVKSLSPQERAAYKEYISNKRKNMTKLRGPNPKSSRTALQSKSESEDDDEEDEDEDEEDDEEEDDENGDSSEDGGDSSESSSEDESEDGDENEEDDEDEDDDEDDDEDEDNESEGSSSSSSSSGDSSDSDSN", "length": 757, "header": "tr|F1MCZ7-1|F1MCZ7_BOVIN Computationally mapped isoform of Nucleolar transcription factor 1 OS=Bos taurus OX=9913 GN=UBTF PE=4 SV=2 CANONICAL=A0AAA9TQ73-1" }, "locus": { "chromosome": "19", "start_pos": 44035192, "end_pos": 44024341, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000034806.6", "url": "https://www.ensembl.org/id/ENSBTAT00000034806.6" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000034691.4", "url": "https://www.ensembl.org/id/ENSBTAP00000034691.4" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [ { "id": "bta:497012", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?bta:497012", "resource": "KEGG Pathway" }, { "id": "R-BTA-73728", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-BTA-73728", "resource": "Reactome", "description": "RNA Polymerase I Promoter Opening" }, { "id": "R-BTA-73762", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-BTA-73762", "resource": "Reactome", "description": "RNA Polymerase I Transcription Initiation" }, { "id": "R-BTA-73772", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-BTA-73772", "resource": "Reactome", "description": "RNA Polymerase I Promoter Escape" }, { "id": "R-BTA-73863", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-BTA-73863", "resource": "Reactome", "description": "RNA Polymerase I Transcription Termination" } ], "orthologs": [ { "uniprot_canonical_ac": "F1QZ83-1", "protein_name": "Nucleolar transcription factor 1", "gene_name": "ubtf", "tax_id": 7955, "organism": "Danio rerio", "sequence": { "sequence": "MNGEMDSSAKATVWVQDDVLKLLDAMKVNLPEKDLAKYKTSESHLDWEKVAFDAYSAEVCKQKWQEVSREIRKFRTLTELIVDAQDYIKNPYKGKKLKKHPDFPKKPLTPYFRFFMEKRAKYAKLHPEMSNLDLTKILSKKYKELPDRKKEKYVKDFLREKETFMLSMMKFKQEHPDLLENVNKKSNVPEKAKTPQQLWYSHEKKAFLKAHPDATTKDIKDNLGKQWPQLSDKKRIKWIAKSLEQHKLYEEKMREFIQQHPEMNMTQGDIVKSSLTKAERQLKDKFDGRPDKPPSNGYSLFCAELMSSMKDVPSTERMVMCSQRWKLLKQAEKDAYQKRCEQKKKEYEVEMNRYLLSISEEEQQRILSEQKMGSFKKAGGISSPASKKKSSKAKPSAEKPKPPISAMFIFSEEKRPKLKQEKPELSDMELTRLLARMWNELTDKKKEKYKTLEMALKAEAEKQSREEKGKLPETPKTAQEIWQQSVIGDYLARFKNDRAKAQKTMEATWNTMEKKEKIVWIKKAAEDQKRYERELSEMRSPAPVITPGKKMKFDGEPKKPPSNGYQKFSQEMLSNGELNHLPMKERMGEIGGRWQRLPQKDKDRYKRIAEEKQRLYKVELEQWLTSISSQERAAYKEYNSLKRRSTAKPGGTNAKVKPKAKRSDDEEDEDEDDDDEDDDKDSDGSSSDDSDDDDDDDDEDNEEDVEDEEVDDKENKSESSSSSSSSDDSSASDSD", "length": 735 }, "evidence": [ { "id": "A0AAA9TQ73", "url": "https://omabrowser.org/oma/group/A0AAA9TQ73/", "database": "OMA" } ], "glygen_name": "Zebrafish", "common_name": "Zebrafish" }, { "uniprot_canonical_ac": "P17480-1", "protein_name": "Nucleolar transcription factor 1", "gene_name": "UBTF", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MNGEADCPTDLEMAAPKGQDRWSQEDMLTLLECMKNNLPSNDSSKFKTTESHMDWEKVAFKDFSGDMCKLKWVEISNEVRKFRTLTELILDAQEHVKNPYKGKKLKKHPDFPKKPLTPYFRFFMEKRAKYAKLHPEMSNLDLTKILSKKYKELPEKKKMKYIQDFQREKQEFERNLARFREDHPDLIQNAKKSDIPEKPKTPQQLWYTHEKKVYLKVRPDATTKEVKDSLGKQWSQLSDKKRLKWIHKALEQRKEYEEIMRDYIQKHPELNISEEGITKSTLTKAERQLKDKFDGRPTKPPPNSYSLYCAELMANMKDVPSTERMVLCSQQWKLLSQKEKDAYHKKCDQKKKDYEVELLRFLESLPEEEQQRVLGEEKMLNINKKQATSPASKKPAQEGGKGGSEKPKRPVSAMFIFSEEKRRQLQEERPELSESELTRLLARMWNDLSEKKKAKYKAREAALKAQSERKPGGEREERGKLPESPKRAEEIWQQSVIGDYLARFKNDRVKALKAMEMTWNNMEKKEKLMWIKKAAEDQKRYERELSEMRAPPAATNSSKKMKFQGEPKKPPMNGYQKFSQELLSNGELNHLPLKERMVEIGSRWQRISQSQKEHYKKLAEEQQKQYKVHLDLWVKSLSPQDRAAYKEYISNKRKSMTKLRGPNPKSSRTTLQSKSESEEDDEEDEDDEDEDEEEEDDENGDSSEDGGDSSESSSEDESEDGDENEEDDEDEDDDEDDDEDEDNESEGSSSSSSSSGDSSDSDSN", "length": 764 }, "evidence": [ { "id": "A0AAA9TQ73", "url": "https://omabrowser.org/oma/group/A0AAA9TQ73/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "P25976-1", "protein_name": "Nucleolar transcription factor 1", "gene_name": "Ubtf", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MNGEADCPTDLEMAAPKGQDRWSQEDMLTLLECMKNNLPSNDSSKFKTTESHMDWEKVAFKDFSGDMCKLKWVEISNEVRKFRTLTELILDAQEHVKNPYKGKKLKKHPDFPKKPLTPYFRFFMEKRAKYAKLHPEMSNLDLTKILSKKYKELPEKKKMKYIQDFQREKQEFERNLARFREDHPDLIQNAKKSDIPEKPKTPQQLWYTHEKKVYLKVRPDATTKEVKDSLGKQWSQLSDKKTLKWIHKALEQRKEYEEIMRDYIQKHPELNISEEGITKSTLTKAERQLKDKFDGRPTKPPPNSYSLYCAELMANMKDVPSTERMVLCSQQWKLLSQKEKDAYHKKCDQKKKDYEVELLRFLESLPEEEQQRVLGEEKMLNINKKQTTSPASKKPSQEGGKGGSEKPKRPVSAMFIFSEEKRRQLQEERPELSESELTRLLARMWNDLTEKKKAKYKAREAALKAQSERKPGGEREDRGKLPESPKRAEEIWQQSVIGDYLARFKNDRVKALKAMEMTWNNMEKKEKLMWIKKAAEDQKRYERELSEMRAPPAATNSSKKMKFQGEPKKPPMNGYQKFSQELLSNGELNHLPLKERMVEIGSRWQRISQSQKEHYKKLAEEQQRQYKVHLDLWVKSLSPQDRAAYKEYISNKRKNMTKLRGPNPKSSRTTLQSKSESEEDDDEEEEDDEEEEEEEEDDENGDSSEDGGDSSESSSEDESEDGDENDDDDDDEDDEDDDDEDEDNESEGSSSSSSSSGDSSDSGSN", "length": 765 }, "evidence": [ { "id": "A0AAA9TQ73", "url": "https://omabrowser.org/oma/group/A0AAA9TQ73/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "P25977-1", "protein_name": "Nucleolar transcription factor 1", "gene_name": "Ubtf", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MNGEADCPTDLEMAAPKGQDRWSQEDMLTLLECMKNNLPSNDSSKFKTTESHMDWEKVAFKDFSGDMCKLKWVEISNEVRKFRTLTELILDAQEHVKNPYKGKKLKKHPDFPKKPLTPYFRFFMEKRAKYAKLHPEMSNLDLTKILSKKYKELPEKKKMKYIQDFQREKQEFERNLARFREDHPDLIQNAKKSDIPEKPKTPQQLWYTHEKKVYLKVRPDATTKEVKDSLGKQWSQLSDKKRLKWIHKALEQRKEYEEIMRDYIQKHPELNISEEGITKSTLTKAERQLKDKFDGRPTKPPPNSYSLYCAELMANMKDVPSTERMVLCSQQWKLLSQKEKDAYHKKCDQKKKDYEVELLRFLESLPEEEQQRVLGEEKMLNINKKQTTSPASKKPSQEGGKGGSEKPKRPVSAMFIFSEEKRRQLQEERPELSESELTRLLARMWNDLSEKKKAKYKAREAALKAQSERKPGGEREDRGKLPESPKRAEEIWQQSVIGDYLARFKNDRVKALKAMEMTWNNMEKKEKLMWIKKAAEDQKRYERELSEMRAPPAATNSSKKMKFQGEPKKPPMNGYQKFSQELLSNGELNHLPLKERMVEIGSRWQRISQSQKEHYKKLAEEQQRQYKVHLDLWVKSLSPQDRAAYKEYISNKRKNMTKLRGPNPKSSRTTLQSKSESEEDDDEEDDDDDDEEEEEDDENGDSSEDGGDSSESSSEDESEDGDENEDDDDDEDDDEDDDEDEDNESEGSSSSSSSSGDSSDSDSN", "length": 764 }, "evidence": [ { "id": "A0AAA9TQ73", "url": "https://omabrowser.org/oma/group/A0AAA9TQ73/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" } ], "go_annotation": { "categories": [ { "name": "Molecular Function", "total": 6, "go_terms": [ { "name": "DNA binding", "id": "GO:0003677", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003677", "evidence": [ { "database": "UniProtKB", "id": "A0AAA9TQ73", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TQ73" } ], "pmid": "" }, { "name": "chromatin binding", "id": "GO:0003682", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003682", "evidence": [ { "database": "UniProtKB", "id": "A0AAA9TQ73", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TQ73" } ], "pmid": "" }, { "name": "scaffold protein binding", "id": "GO:0097110", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0097110", "evidence": [ { "database": "UniProtKB", "id": "A0AAA9TQ73", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TQ73" } ], "pmid": "" }, { "name": "RNA polymerase I core promoter sequence-specific DNA binding", "id": "GO:0001164", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0001164", "evidence": [ { "database": "UniProtKB", "id": "A0AAA9TQ73", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TQ73" } ], "pmid": "" }, { "name": "RNA polymerase I cis-regulatory region sequence-specific DNA binding", "id": "GO:0001165", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0001165", "evidence": [ { "database": "UniProtKB", "id": "A0AAA9TQ73", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TQ73" } ], "pmid": "" }, { "name": "RNA polymerase I general transcription initiation factor activity", "id": "GO:0001181", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0001181", "evidence": [ { "database": "UniProtKB", "id": "A0AAA9TQ73", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TQ73" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 3, "go_terms": [ { "name": "nucleolus", "id": "GO:0005730", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005730", "evidence": [ { "database": "UniProtKB", "id": "A0AAA9TQ73", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TQ73" } ], "pmid": "" }, { "name": "nucleus", "id": "GO:0005634", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005634", "evidence": [ { "database": "UniProtKB", "id": "A0AAA9TQ73", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TQ73" } ], "pmid": "" }, { "name": "fibrillar center", "id": "GO:0001650", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0001650", "evidence": [ { "database": "UniProtKB", "id": "A0AAA9TQ73", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TQ73" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 3, "go_terms": [ { "name": "DNA-templated transcription", "id": "GO:0006351", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006351", "evidence": [ { "database": "UniProtKB", "id": "A0AAA9TQ73", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TQ73" } ], "pmid": "" }, { "name": "transcription by RNA polymerase I", "id": "GO:0006360", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006360", "evidence": [ { "database": "UniProtKB", "id": "A0AAA9TQ73", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TQ73" } ], "pmid": "" }, { "name": "positive regulation of transcription by RNA polymerase I", "id": "GO:0045943", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0045943", "evidence": [ { "database": "UniProtKB", "id": "A0AAA9TQ73", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TQ73" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 234, "end_pos": 236, "annotation": "n_glycosylation_sequon" }, { "start_pos": 41, "end_pos": 43, "annotation": "n_glycosylation_sequon" }, { "start_pos": 512, "end_pos": 514, "annotation": "n_glycosylation_sequon" }, { "start_pos": 611, "end_pos": 613, "annotation": "n_glycosylation_sequon" }, { "start_pos": 699, "end_pos": 701, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], 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"start_pos": 611, "end_pos": 613 }, { "start_pos": 699, "end_pos": 701 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", 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"MGKDQGFSRHFRIFIPKKHRARFDEVVSQGLLGKLCRARRTQGAQRLRRSRSEERPERLLVSTRASAAPRRPDEPPPRKAASLLGGRAGPGGARRTVRVYKGNKSFGFTLRGHGPVWIESVLPGSPADNASLKSGDQILFLNGLDMRNCSHDKVVSMLQGSGAMPTLVVEEGLVPFASDSDSMDSPNPSSALTSLQWVAEILPSSIRVQGRTFSQQLEHLLTPPERYGVCRALESFFQHRNIDTLIVDVYPVLDTPAKQVLWQFIYQLLTYEEQELCQEKIACFLGYTAMTEPEPEPEPELEPEPAPEPQMRSSLRASSMCRRSLRSQGLEAGLGCGPSDCPEMPLPPIPGERQAGDGTSLPETPNPKMMSAVYAELESRLSSSFKGKMGTSSRARASPPLPSAAGPAGPRTRSSISWPSEQLLPSPCYYPLCSEGLASPSSSESHPYASLDSSRAPSPQPGPGPVCAESPPSPDPSRRPSSRRKLFAFSRPVRSRDTDRFLDALSEQLGPRVTIVEDFLSPENDYEEMSFHDDQGSFITNERSSASECISSSEEGSSLTYSSLSDHIPPPPLSPPPPPPLPFHDPKPSSSRTPDGPRGPTPALPKPLAQLGHPVPPPPPPPLPPPVPCAPPMLPRGLGHRRSETSHMSVKRLRWEQVENSEGTIWGQLGEDSDYDKLSDMVKYLDLELHFGTQKAAKPVPGPEPFRKKEVVEILSHKKAYNTSILLAHLKLSPAELRQVLMSMEPRRLEPAHLAQLLLFAPDADEEQRYQAYREAPGRLSEPDQFVLQMLSVPEYKTRLRSLHFQATLQEKTEEIRGSLECLRQASLELKNSRKLAKILEFVLAMGNYLNDGQPQTNKTTGFKINFLTELNSTKTVDGKSTFLHILAKSLSQHFPELLGFAQDLPTVPLAAKVNQRALTNDLADLHGTISEIQAACQSMSPSSEDKFAVVMASFLETAQPLLRALDGLQREAMEELGKALAFFGEDSKATTSEAFFGIFAEFMSKFERALGDLQAAEGPRSSGMVSPLAW", "length": 1031, "header": "tr|A0AAA9TQJ1-1|A0AAA9TQJ1_BOVIN Isoform 1 of Delphilin OS=Bos taurus OX=9913 GN=GRID2IP PE=4 SV=1 CANONICAL=A0AAA9TQJ1-1" }, "isoforms": [ { "isoform_ac": "A0AAA9SGN6-1", "url": "https://www.uniprot.org/uniprotkb/A0AAA9SGN6/entry", "sequence": { "sequence": "MSCLGIFIPKKHRARFDEVVSQGLLGKLCRARRTQGAQRLRRSRSEERPERLLVSTRASAAPRRPDEPPPRKAASLLGGRAGPGGARRTVRVYKGNKSFGFTLRGHGPVWIESVLPGSPADNASLKSGDQILFLNGLDMRNCSHDKVVSMLQGSGAMPTLVVEEGLVPFASDSDSMDSPNPSSALTSLQWVAEILPSSIRVQGRTFSQQLEHLLTPPERYGVCRALESFFQHRNIDTLIVDVYPVLDTPAKQVLWQFIYQLLTYEEQELCQEKIACFLGYTAMTEPEPEPEPELEPEPAPEPQMRSSLRASSMCRRSLRSQGLEAGLGCGPSDCPEMPLPPIPGERQAGDGTSLPETPNPKMMSAVYAELESRLSSSFKGKMGTSSRARASPPLPSAAGPAGPRTRSSISWPSEQLLPSPCYYPLCSEGLASPSSSESHPYASLDSSRAPSPQPGPGPVCAESPPSPDPSRRPSSRRKLFAFSRPVRSRDTDRFLDALSEQLGPRVTIVEDFLSPENDYEEMSFHDDQGSFITNERSSASECISSSEEGSSLTYSSLSDHIPPPPLSPPPPPPLPFHDPKPSSSRTPDGPRGPTPALPKPLAQLGHPVPPPPPPPLPPPVPCAPPMLPRGLGHRRSETSHMSVKRLRWEQVENSEGTIWGQLGEDSDYDKLSDMVKYLDLELHFGTQKAAKPVPGPEPFRKKEVVEILSHKKAYNTSILLAHLKLSPAELRQVLMSMEPRRLEPAHLAQLLLFAPDADEEQRYQAYREAPGRLSEPDQFVLQMLSVPEYKTRLRSLHFQATLQEKTEEIRGSLECLRQASLELKNSRKLAKILEFVLAMGNYLNDGQPQTNKTTGFKINFLTELNSTKTVDGKSTFLHILAKSLSQHFPELLGFAQDLPTVPLAAKVNQRALTNDLADLHGTISEIQAACQSMSPSSEDKFAVVMASFLETAQPLLRALDGLQREAMEELGKALAFFGEDSKATTSEAFFGIFAEFMSKFERALGDLQAAEGPRSSGMVSPLAW", "length": 1024, "header": "tr|A0AAA9SGN6-1|A0AAA9TQJ1_BOVIN Computationally mapped isoform of Delphilin OS=Bos taurus OX=9913 GN=GRID2IP PE=4 SV=1 CANONICAL=A0AAA9TQJ1-1" }, "locus": { "chromosome": "25", "start_pos": 38381984, "end_pos": 38359041, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000120169.1", "url": "https://www.ensembl.org/id/ENSBTAT00000120169.1" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000085346.1", "url": "https://www.ensembl.org/id/ENSBTAP00000085346.1" } ] } }, { "isoform_ac": "A0AAA9TQJ1-1", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TQJ1/entry", "sequence": { "sequence": "MGKDQGFSRHFRIFIPKKHRARFDEVVSQGLLGKLCRARRTQGAQRLRRSRSEERPERLLVSTRASAAPRRPDEPPPRKAASLLGGRAGPGGARRTVRVYKGNKSFGFTLRGHGPVWIESVLPGSPADNASLKSGDQILFLNGLDMRNCSHDKVVSMLQGSGAMPTLVVEEGLVPFASDSDSMDSPNPSSALTSLQWVAEILPSSIRVQGRTFSQQLEHLLTPPERYGVCRALESFFQHRNIDTLIVDVYPVLDTPAKQVLWQFIYQLLTYEEQELCQEKIACFLGYTAMTEPEPEPEPELEPEPAPEPQMRSSLRASSMCRRSLRSQGLEAGLGCGPSDCPEMPLPPIPGERQAGDGTSLPETPNPKMMSAVYAELESRLSSSFKGKMGTSSRARASPPLPSAAGPAGPRTRSSISWPSEQLLPSPCYYPLCSEGLASPSSSESHPYASLDSSRAPSPQPGPGPVCAESPPSPDPSRRPSSRRKLFAFSRPVRSRDTDRFLDALSEQLGPRVTIVEDFLSPENDYEEMSFHDDQGSFITNERSSASECISSSEEGSSLTYSSLSDHIPPPPLSPPPPPPLPFHDPKPSSSRTPDGPRGPTPALPKPLAQLGHPVPPPPPPPLPPPVPCAPPMLPRGLGHRRSETSHMSVKRLRWEQVENSEGTIWGQLGEDSDYDKLSDMVKYLDLELHFGTQKAAKPVPGPEPFRKKEVVEILSHKKAYNTSILLAHLKLSPAELRQVLMSMEPRRLEPAHLAQLLLFAPDADEEQRYQAYREAPGRLSEPDQFVLQMLSVPEYKTRLRSLHFQATLQEKTEEIRGSLECLRQASLELKNSRKLAKILEFVLAMGNYLNDGQPQTNKTTGFKINFLTELNSTKTVDGKSTFLHILAKSLSQHFPELLGFAQDLPTVPLAAKVNQRALTNDLADLHGTISEIQAACQSMSPSSEDKFAVVMASFLETAQPLLRALDGLQREAMEELGKALAFFGEDSKATTSEAFFGIFAEFMSKFERALGDLQAAEGPRSSGMVSPLAW", "length": 1031, "header": "tr|A0AAA9TQJ1-1|A0AAA9TQJ1_BOVIN Isoform 1 of Delphilin OS=Bos taurus OX=9913 GN=GRID2IP PE=4 SV=1 CANONICAL=A0AAA9TQJ1-1" }, "locus": { "chromosome": "25", "start_pos": 38377887, "end_pos": 38359041, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000110479.1", "url": "https://www.ensembl.org/id/ENSBTAT00000110479.1" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000100638.1", "url": "https://www.ensembl.org/id/ENSBTAP00000100638.1" } ] } }, { "isoform_ac": "E1BFV9-1", "url": "https://www.uniprot.org/uniprotkb/E1BFV9/entry", "sequence": { "sequence": "TAATAMPATNQGWPEDFGFRLGGSGPCFVLDVVEGSSAHAGGLRPGDQILEVEGLAVAGLSRERLVRLARRCPRVPPSLGVLPGPIGGPGAGSGCEPLTTALRIQRSSRGLYLGRELLRLAGRKRPDAVHRERRRKAQEFSRKVDETLGDQPTAKEQVFAALKQFAAEQRVDELVWALTLALPTEARGPLLENLRIFIPKKHRARFDEVVSQGLLGKLCRARRTQGAQRLRRSRSEERPERLLVSTRASAAPRRPDEPPPRKAASLLGGRAGPGGARRTVRVYKGNKSFGFTLRGHGPVWIESVLPGSPADNASLKSGDQILFLNGLDMRNCSHDKVVSMLQGSGAMPTLVVEEGLVPFASDSDSMDSPNPSSALTSLQWVAEILPSSIRVQGRTFSQQLEHLLTPPERYGVCRALESFFQHRNIDTLIVDVYPVLDTPAKQVLWQFIYQLLTYEEQELCQEKIACFLGYTAMTAEPEPEPEPELEPEPAPEPQMRSSLRASSMCRRSLRSQGLEAGLGCGPSDCPEMPLPPIPGERQAGDGTSLPETPNPKMMSAVYAELESRLSSSFKGKMGTSSRARASPPLPSAAGPAGPRTRSSISWPSEQLLPSPCYYPLCSEGLASPSSSESHPYASLDSSRAPSPQPGPGPVCAESPPSPDPSRRPSSRRKLFAFSRPVRSRDTDRFLDALSEQLGPRVTIVEDFLSPENDYEEMSFHDDQGSFITNERSSASECISSSEEGSSLTYSSLSDHIPPPPLSPPPPPPLPFHDPKPSSSRTPDGPRGPTPALPKPLAQLGHPVPPPPPPPLPPPVPCAPPMLPRGLGHRRSETSHMSVKRLRWEQVENSEGTIWGQLGEDSDYDKLSDMVKYLDLELHFGTQKAAKPVPGPEPFRKKEVVEILSHKKAYNTSILLAHLKLSPAELRQVLMSMEPRRLEPAHLAQLLLFAPDADEEQRYQAYREAPGRLSEPDQFVLQMLSVPEYKTRLRSLHFQATLQEKTEEIRGSLECLRQASLELKNSRKLAKILEFVLAMGNYLNDGQPQTNKTTGFKINFLTELNSTKTVDGKSTFLHILAKSLSQHFPELLGFAQDLPTVPLAAKVNQRALTNDLADLHGTISEIQAACQSMSPSSEDKFAVVMASFLETAQPLLRALDGLQREAMEELGKALAFFGEDSKATTSEAFFGIFAEFMSKFERALGDLQAAEGPRSSGMVSPLAW", "length": 1215, "header": "tr|E1BFV9-1|E1BFV9_BOVIN Computationally mapped isoform of Delphilin OS=Bos taurus OX=9913 GN=GRID2IP PE=4 SV=4 CANONICAL=A0AAA9TQJ1-1" }, "locus": { "chromosome": "25", "start_pos": 38390771, "end_pos": 38359041, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000004281.7", "url": "https://www.ensembl.org/id/ENSBTAT00000004281.7" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000004281.7", "url": "https://www.ensembl.org/id/ENSBTAP00000004281.7" } ] } } ], "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "other", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 601, "start_aa": "Thr", "end_pos": 601, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr601", "evidence": [ { "id": "", "database": "GlyGen", "url": "https://data.glygen.org/" } ], "filter_code": "000000000000000010000.00000000001000.0.01000" } ], "phosphorylation": [], "glycation": [], "keywords": [ "glycoprotein", "glycoprotein_predicted" ], "publication": [], "pathway": [], "orthologs": [], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 4, "go_terms": [ { "name": "postsynaptic membrane", "id": "GO:0045211", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0045211", "evidence": [ { "database": "UniProtKB", "id": "A0AAA9TQJ1", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TQJ1" } ], "pmid": "" }, { "name": "postsynaptic density, intracellular component", "id": "GO:0099092", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0099092", "evidence": [ { "database": "UniProtKB", "id": "A0AAA9TQJ1", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TQJ1" } ], "pmid": "" }, { "name": "parallel fiber to Purkinje cell synapse", "id": "GO:0098688", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0098688", "evidence": [ { "database": "UniProtKB", "id": "A0AAA9TQJ1", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TQJ1" } ], "pmid": "" }, { "name": "cerebellar granule cell to Purkinje cell synapse", "id": "GO:0150048", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0150048", "evidence": [ { "database": "UniProtKB", "id": "A0AAA9TQJ1", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TQJ1" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 2, "go_terms": [ { "name": "regulation of postsynaptic membrane neurotransmitter receptor levels", "id": "GO:0099072", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0099072", "evidence": [ { "database": "UniProtKB", "id": "A0AAA9TQJ1", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TQJ1" } ], "pmid": "" }, { "name": "regulation of postsynaptic cytosolic calcium ion concentration", "id": "GO:0099566", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0099566", "evidence": [ { "database": "UniProtKB", "id": "A0AAA9TQJ1", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TQJ1" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 103, "end_pos": 105, "annotation": "n_glycosylation_sequon" }, { "start_pos": 129, "end_pos": 131, "annotation": "n_glycosylation_sequon" }, { "start_pos": 148, "end_pos": 150, "annotation": "n_glycosylation_sequon" }, { "start_pos": 722, "end_pos": 724, "annotation": "n_glycosylation_sequon" }, { "start_pos": 858, "end_pos": 860, "annotation": "n_glycosylation_sequon" }, { "start_pos": 872, "end_pos": 874, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A0AAA9TQJ1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TQJ1" }, { "id": "PS51444", "database": "PROSITE", "url": "https://prosite.expasy.org/PS51444" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "FH2", "eco_id": "ECO_0000259", "start_pos": 640, "end_pos": 1031, "start_aa": "His", "end_aa": "Trp", "glycosite_overlap": [] }, { "evidence": [ { "id": "A0AAA9TQJ1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TQJ1" }, { "id": "PS50106", "database": "PROSITE", "url": "https://prosite.expasy.org/PS50106" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "PDZ", "eco_id": "ECO_0000259", "start_pos": 96, "end_pos": 173, "start_aa": "Thr", "end_aa": "Leu", "glycosite_overlap": [] } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [ 601 ], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 103, "end_pos": 105 }, { "start_pos": 129, "end_pos": 131 }, { "start_pos": 148, "end_pos": 150 }, { "start_pos": 722, "end_pos": 724 }, { "start_pos": 858, "end_pos": 860 }, { "start_pos": 872, "end_pos": 874 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 1 }, { "field": "total_sites", "count": 1 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 1 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "exact_sites", "count": 1 }, { "field": "exact_o_linked_sites", "count": 1 }, { "field": "fuzzy_sites", "count": 0 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_pos", "start_aa", "end_pos", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", 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"sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ], "tool_support": { "graph_view": "yes" } }, { "uniprot_canonical_ac": "A0AAA9TPH5-1", "uniprot_ac": "A0AAA9TPH5", "uniprot_id": "A0AAA9TPH5_BOVIN", "mass": { "chemical_mass": 13429.0, "monoisotopic_mass": 13429.0 }, "refseq": {}, "gene_names": [ { "name": "PPP1R14A", "type": "recommended", "evidence": 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CANONICAL=A0AAA9TNX3-1" }, "locus": { "chromosome": "25", "start_pos": 38734652, "end_pos": 38625577, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000124343.2", "url": "https://www.ensembl.org/id/ENSBTAT00000124343.2" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000092620.1", "url": "https://www.ensembl.org/id/ENSBTAP00000092620.1" } ] } }, { "isoform_ac": "A0AAA9TNX3-1", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TNX3/entry", "sequence": { "sequence": "MAEGNSSEEVIHLNNFHCHRGQDWINLRDGPITISDSSDEEGVPMLVTPAPQQHDEDLDDDVILAETYKPQTSRPNLIKPAAQWQDLKRLGEERPKKSRAAFESDTNGYFPVYNSSLFGSGTQDDSEDDYSEFLDLGPPGVSGFMKPSGQTEREPKPGPSHNQATNDFINPRSEQKVIILKEGNLFPEADPLDTQNQSSEESETELLSNLGESSDILDDQAIEEDCWLDHSYFQSLNQQPREVPSQVVPQERRPEAELGPLLYQHEPRGSAFPRPAFARPEPQQDWIPDPASPRPAHPLGELEDQQLAIDDEEPGPAFPLEETRQPNLGNLWGQEASYVDRELIALLVKETEVRFPDVANGYVEEIIHLKNYYDLNVLCNFLLENPDYPKREDRVLMNPSSSLLASQDEMKLPTVDFFDYSKLAPLDQHCFIQAADLLMADFKMLSSQDIKWALHELKGHYAITRKAFSDAIKKWQELSPETSGKRKKRKEMNQYSYIDFKFEQGDKKIEKRMFFLENKRRHCRSYDRRALLPAVQQEQEFYEQKIKEMAEHEDFLLALQMNEEQYQKDGQLIECRCCYGEFPFEELTQCADAHLFCKECLIRYAQEAVFGSGKSELSCMEGSCTCSFPASELEKVLPQTILYKYYERKAEEEVAAAYADELVRCPSCSFPALLDSDVKRFSCPNPRCRKETCRKCQGLWKEHNGLTCEELAEKDDIKYRTSIEEKMTAARIRKCHKCGTSLIKSEGCNRMSCRCGAQMCYLCRVSINGYDHFCQHPRSPGAPCQECSRCSLWTDPTEDDEKLIEEIQKEAEEEQKRKNGENTFKRIGPPLEKPPEKVQRTEALPRPVPQNLHQPQIPAYAFVHPPFPLPPVRPVFNNFPLNMGPIPAPYVPPLPNMRVNYEFAPIHLPLEHNLPMHFGPQPRHRF", "length": 926, "header": "tr|A0AAA9TNX3-1|A0AAA9TNX3_BOVIN Isoform 1 of E3 ubiquitin-protein ligase RNF216 OS=Bos taurus OX=9913 GN=RNF216 PE=4 SV=2 CANONICAL=A0AAA9TNX3-1" }, "locus": { "chromosome": "25", "start_pos": 38734652, "end_pos": 38625577, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000120364.2", "url": "https://www.ensembl.org/id/ENSBTAT00000120364.2" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000098031.2", "url": "https://www.ensembl.org/id/ENSBTAP00000098031.2" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [ "enzyme" ], "publication": [], "pathway": [], "orthologs": [], "go_annotation": { "categories": [ { "name": "Molecular Function", "total": 3, "go_terms": [ { "name": "zinc ion binding", "id": "GO:0008270", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008270", "evidence": [ { "database": "UniProtKB", "id": "A0AAA9TNX3", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TNX3" } ], "pmid": "" }, { "name": "ubiquitin protein ligase activity", "id": 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"enzyme_annotation": [ { "ec_number": "2.3.2.27", "ec_name": "S-ubiquitinyl-[E2 ubiquitin-conjugating enzyme]-L-cysteine + [acceptor protein]-L-lysine = [E2 ubiquitin-conjugating enzyme]-L-cysteine + N(6)-ubiquitinyl-[acceptor protein]-L-lysine.", "evidence": [ { "id": "2.3.2.27", "database": "BRENDA Enzymes", "url": "https://www.brenda-enzymes.org/enzyme.php?ecno=2.3.2.27" } ] } ], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 114, "end_pos": 116 }, { "start_pos": 196, "end_pos": 198 }, { "start_pos": 5, "end_pos": 7 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": 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Probably acts via the piRNA metabolic process, which mediates the repression of transposable elements during meiosis by forming complexes composed of piRNAs and Piwi proteins and govern the methylation and subsequent repression of transposons. 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Classification" ] }, { "id": "IPR041966", "url": "https://www.ebi.ac.uk/interpro/entry/IPR041966", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR050621", "url": "https://www.ebi.ac.uk/interpro/entry/IPR050621", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "bta:537634", "url": "https://www.genome.jp/dbget-bin/www_bget?bta:537634", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "PTHR22948", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR22948", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR22948:SF19", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR22948:SF19", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00567", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00567", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF12872", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF12872", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "A0A3Q1N5R0", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1N5R0", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A3Q1N5R0-1", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1N5R0-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0AAA9TUB3", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TUB3", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0AAA9TUB3-1", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TUB3-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0AAA9TUL2", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TUL2", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0AAA9TUL2-1", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TUL2-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "G5E528", "url": "https://www.uniprot.org/uniprotkb/G5E528", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "G5E528-1", "url": "https://www.uniprot.org/uniprotkb/G5E528-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MNRGGGRVGTAVLTAAIRITWGFPGSSAGKESTCNTGDPCPITWVGNIPWREDRLPTPMFLGFPDDSDGKESACNAGELGFWEPIPGLGRSPGGGHGNPLQYSCLKNPHGRRSLVGSNSWGHKKSDTTERLSAAQNHLEGAMSEQERIQECLRKEIRSLLISTKDGLTPQQLEKEYLLMVGNHLPLRILGYRSTMELVLDMPDVVSVCPCGDGTVILKAIPDESTKGIANLVAKQKSNHKVRNSMQKGRASVCSGPSSRRRVPYRGRVPPILPAVVKSELKDLLALSPVLLSDFENAFANRFGRSFQYVQYGFLSMFEVLNAASDVISVEQTRAGSLLTLKKSVSEEKQRGWPAGKIFTQPFRMKQQGSYPIGFPVAKACFSQPTSNMEPPKQILGMERNSRSNVMETSRLNHSEKLNQLENTFKSVIAQIGPGGTINPELKHKIKFVVSRFPEGLLISKLLREFELIFKEQLSPKKLGFLNVIELVGALSDILHVEFREGEQDLLVFDADMKPLASDGAVSSVRNSFLVQPDKKTEAKACVSSPPRNSLSTAVIKETTWDCPSKNHKEPEQKIFKKPNLVVKPLQLQVEINKSQLSLAVANHDIPPDAVRDKKLCRLPPLDTSTLVGVFVEYILSPSQFYIRIYSRDSSELLEDMMIEMRRCYSNQLVSDRYAMPECFIQPGHLCCVRISEDKWWYRVIIHRILGKQEVEVFYPDFGNIGTVQKSSLRFLKCCYTKLPAQAIPCSLAWVRPVEEHWTSRAVLQFQKLCGLKPLVGVVDEYVDGILNIFLCDTSSNEDVYFHHVLRTEGHAIVCRENVPSKGFRDLNPLALYTKSSVTPEDIVLKELGYHSQQHYFNEDREISPQSKESDLYTLQDINDEKTFSHLGSVTSDEPLKDSKLNSLKIQDKSYEEDPKWSIPELKDLKEENEDEIPTGMPYLESVTIGDDIWDENWLPLQAKMGKESDAASHLFTSSLGGKKPYPSCKEIPQKDWCFSTPKDIWDDSWQPSGLVNGMKVEVQIPEGLGAQEKHIDTTRIQKQSNVKSASDSPALPKLEEFYISLIQSQQSAEGSQFEPSNIQTPPKQIQLSSTPTLVNSGSVEGSPESLENEDFSSSSAITVFKDTSQGAVDQLSLILSPEHQISQKFYIPRSTATAALGAAARLATSNSLLHWYPSVKKMET", "length": 1180, "header": "tr|A0AAA9TUL2-1|A0AAA9TUL2_BOVIN Isoform 1 of Tudor domain-containing protein 5 OS=Bos taurus OX=9913 GN=TDRD5 PE=3 SV=1 CANONICAL=A0AAA9TUL2-1" }, "isoforms": [ { "isoform_ac": "A0A3Q1N5R0-1", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1N5R0/entry", "sequence": { "sequence": "MSEQERIQECLRKEIRSLLISTKDGLTPQQLEKEYLLMVGNHLPLRILGYRSTMELVLDMPDVVSVCPCGDGTVILKAIPDESTKGIANLVAKQKSNHKVRNSMQKGRASVCSGPSSRRRVPYRGRVPPILPAVVKSELKDLLALSPVLLSDFENAFANRFGRSFQYVQYGFLSMFEVLNAASDVISVEQTRAGSLLTLKKSVSEEKQRGWPAGKIFTQPFRMKQQGSYPIGFPVAKACFSQPTSNMEPPKQILGMERNSRSNVMETSRLNHSEKLNQLENTFKSVIAQIGPGGTINPELKHKIKFVVSRFPEGLLISKLLREFELIFKEQLSPKKLGFLNVIELVGALSDILHVEFREGEQDLLVFDADMKPLASVQPDKKTEAKACVSSPPRNSLSTAVIKETTWDCPSKNHKEPEQKIFKKPNLVVKPLQLQVEINKSQLSLAVANHDIPPDAVRDKKLCRLPPLDTSTLVGVFVEYILSPSQFYIRIYSRDSSELLEDMMIEMRRCYSNQLVSDRYAMPECFIQPGHLCCVRISEDKWWYRVIIHRILGKQEVEVFYPDFGNIGTVQKSSLRFLKCCYTKLPAQAIPCSLAWVRPVEEHWTSRAVLQFQKLCGLKPLVGVVDEYVDGILNIFLCDTSSNEDVYFHHVLRTEGHAIVCRENVPSKGFRDLNPLALYTKSSVTPEDIVLKELGYHSQQHYFNEDREISPQSKESDLYTLDEIPTGMPYLESVTIGDDIWDENWLPLQAKMGKESDAASHLFTSSLGGKKPYPSCKEIPQKDWCFSTPKDIWDDSWQPSGLVNGMKVEVQIPEGLGAQEKHIDTTRIQKQSNVKSASDSPALPKLEEFYISLIQSQQSAEGSQFEPSNIQTPPKQIQLSSTPTLVNSGSVEGSPESLENEDFSSSSAITVFKDTSQGAVDQLSLILSPEHQISQKFYIPRSTATAALGAAARLATSNSLLHWYPSVKKMET", "length": 972, "header": "tr|A0A3Q1N5R0-1|A0AAA9TUL2_BOVIN Computationally mapped isoform of Tudor domain-containing protein 5 OS=Bos taurus OX=9913 GN=TDRD5 PE=3 SV=1 CANONICAL=A0AAA9TUL2-1" }, "locus": { "chromosome": "16", "start_pos": 60894703, "end_pos": 60817250, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000082414.3", "url": "https://www.ensembl.org/id/ENSBTAT00000082414.3" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000065585.1", "url": "https://www.ensembl.org/id/ENSBTAP00000065585.1" } ] } }, { "isoform_ac": "A0AAA9TUB3-1", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TUB3/entry", "sequence": { "sequence": "MAVLDLGGCPQAFSSCSDPWLLSSCSGQAHCNGFSSFGVWYKWISNSTKLFPNQYFKIKIKLQAWNWPQGLTPAAQEPPPRSRPFVGLVLSCAASLRTGSASSGAPELRKLAAPSFLQQFSAMSEQERIQECLRKEIRSLLISTKDGLTPQQLEKEYLLMVGNHLPLRILGYRSTMELVLDMPDVVSVCPCGDGTVILKAIPDESTKGIANLVAKQKSNHKVRNSMQKGRASVCSGPSSRRRVPYRGRVPPILPAVVKSELKDLLALSPVLLSDFENAFANRFGRSFQYVQYGFLSMFEVLNAASDVISVEQTRAGSLLTLKKSVSEEKQRGWPAGKIFTQPFRMKQQGSYPIGFPVAKACFSQPTSNMEPPKQILGMERNSRSNVMETSRLNHSEKLNQLENTFKSVIAQIGPGGTINPELKHKIKFVVSRFPEGLLISKLLREFELIFKEQLSPKKLGFLNVIELVGALSDILHVEFREGEQDLLVFDADMKPLASDGAVSSVRNSFLVQPDKKTEAKACVSSPPRNSLSTAVIKETTWDCPSKNHKEPEQKIFKKPNLVVKPLQLQVEINKSQLSLAVANHDIPPDAVRDKKLCRLPPLDTSTLVGVFVEYILSPSQFYIRIYSRDSSELLEDMMIEMRRCYSNQLVSDRYAMPECFIQPGHLCCVRISEDKWWYRVIIHRILGKQEVEVFYPDFGNIGTVQKSSLRFLKCCYTKLPAQAIPCSLAWVRPVEEHWTSRAVLQFQKLCGLKPLVGVVDEYVDGILNIFLCDTSSNEDVYFHHVLRTEGHAIVCRENVPSKGFRDLNPLALYTKSSVTPEDIVLKELGYHSQQHYFNEDREISPQSKESDLYTLQDINDEKTFSHLGSVTSDEPLKDSKLNSLKIQDKSYEEDPKWSIPELKDLKEENEDEIPTGMPYLESVTIGDDIWDENWLPLQAKMGKESDAASHLFTSSLGGKKPYPSCKEIPQKDWCFSTPKDIWDDSWQPSGLVNGMKVEVQIPEGLGAQEKHIDTTRIQKQSNVKSASDSPALPKLEEFYISLIQSQQSAEGSQFEPSNIQTPPKQIQLSSTPTLVNSGSVEGSPESLENEDFSSSSAITVFKDTSQGAVDQLSLILSPEHQISQKFYIPRSTATAALGAAARLATSNSLLHWYPSVKKMET", "length": 1161, "header": "tr|A0AAA9TUB3-1|A0AAA9TUB3_BOVIN Computationally mapped isoform of Tudor domain-containing protein 5 OS=Bos taurus OX=9913 GN=TDRD5 PE=3 SV=1 CANONICAL=A0AAA9TUL2-1" }, "locus": { "chromosome": "16", "start_pos": 60894703, "end_pos": 60811613, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000120849.2", "url": "https://www.ensembl.org/id/ENSBTAT00000120849.2" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000100695.1", "url": "https://www.ensembl.org/id/ENSBTAP00000100695.1" } ] } }, { "isoform_ac": "A0AAA9TUL2-1", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TUL2/entry", "sequence": { "sequence": "MNRGGGRVGTAVLTAAIRITWGFPGSSAGKESTCNTGDPCPITWVGNIPWREDRLPTPMFLGFPDDSDGKESACNAGELGFWEPIPGLGRSPGGGHGNPLQYSCLKNPHGRRSLVGSNSWGHKKSDTTERLSAAQNHLEGAMSEQERIQECLRKEIRSLLISTKDGLTPQQLEKEYLLMVGNHLPLRILGYRSTMELVLDMPDVVSVCPCGDGTVILKAIPDESTKGIANLVAKQKSNHKVRNSMQKGRASVCSGPSSRRRVPYRGRVPPILPAVVKSELKDLLALSPVLLSDFENAFANRFGRSFQYVQYGFLSMFEVLNAASDVISVEQTRAGSLLTLKKSVSEEKQRGWPAGKIFTQPFRMKQQGSYPIGFPVAKACFSQPTSNMEPPKQILGMERNSRSNVMETSRLNHSEKLNQLENTFKSVIAQIGPGGTINPELKHKIKFVVSRFPEGLLISKLLREFELIFKEQLSPKKLGFLNVIELVGALSDILHVEFREGEQDLLVFDADMKPLASDGAVSSVRNSFLVQPDKKTEAKACVSSPPRNSLSTAVIKETTWDCPSKNHKEPEQKIFKKPNLVVKPLQLQVEINKSQLSLAVANHDIPPDAVRDKKLCRLPPLDTSTLVGVFVEYILSPSQFYIRIYSRDSSELLEDMMIEMRRCYSNQLVSDRYAMPECFIQPGHLCCVRISEDKWWYRVIIHRILGKQEVEVFYPDFGNIGTVQKSSLRFLKCCYTKLPAQAIPCSLAWVRPVEEHWTSRAVLQFQKLCGLKPLVGVVDEYVDGILNIFLCDTSSNEDVYFHHVLRTEGHAIVCRENVPSKGFRDLNPLALYTKSSVTPEDIVLKELGYHSQQHYFNEDREISPQSKESDLYTLQDINDEKTFSHLGSVTSDEPLKDSKLNSLKIQDKSYEEDPKWSIPELKDLKEENEDEIPTGMPYLESVTIGDDIWDENWLPLQAKMGKESDAASHLFTSSLGGKKPYPSCKEIPQKDWCFSTPKDIWDDSWQPSGLVNGMKVEVQIPEGLGAQEKHIDTTRIQKQSNVKSASDSPALPKLEEFYISLIQSQQSAEGSQFEPSNIQTPPKQIQLSSTPTLVNSGSVEGSPESLENEDFSSSSAITVFKDTSQGAVDQLSLILSPEHQISQKFYIPRSTATAALGAAARLATSNSLLHWYPSVKKMET", "length": 1180, "header": "tr|A0AAA9TUL2-1|A0AAA9TUL2_BOVIN Isoform 1 of Tudor domain-containing protein 5 OS=Bos taurus OX=9913 GN=TDRD5 PE=3 SV=1 CANONICAL=A0AAA9TUL2-1" }, "locus": { "chromosome": "16", "start_pos": 60894703, "end_pos": 60812179, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000105525.2", "url": "https://www.ensembl.org/id/ENSBTAT00000105525.2" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000102317.1", "url": "https://www.ensembl.org/id/ENSBTAP00000102317.1" } ] } }, { "isoform_ac": "G5E528-1", "url": "https://www.uniprot.org/uniprotkb/G5E528/entry", "sequence": { "sequence": "MSEQERIQECLRKEIRSLLISTKDGLTPQQLEKEYLLMVGNHLPLRILGYRSTMELVLDMPDVVSVCPCGDGTVILKAIPDESTKGIANLVAKQKSNHKVRNSMQKGRASVCSGPSSRRRVPYRGRVPPILPAVVKSELKDLLALSPVLLSDFENAFANRFGRSFQYVQYGFLSMFEVLNAASDVISVEQTRAGSLLTLKKSVSEEKQRGWPAGKIFTQPFRMKQQGSYPIGFPVAKACFSQPTSNMEPPKQILGMERNSRSNVMETSRLNHSEKLNQLENTFKSVIAQIGPGGTINPELKHKIKFVVSRFPEGLLISKLLREFELIFKEQLSPKKLGFLNVIELVGALSDILHVEFREGEQDLLVFDADMKPLASDGAVSSVRNSFLVQPDKKTEAKACVSSPPRNSLSTAVIKETTWDCPSKNHKEPEQKIFKKPNLVVKPLQLQVEINKSQLSLAVANHDIPPDAVRDKKLCRLPPLDTSTLVGVFVEYILSPSQFYIRIYSRDSSELLEDMMIEMRRCYSNQLVSDRYAMPECFIQPGHLCCVRISEDKWWYRVIIHRILGKQEVEVFYPDFGNIGTVQKSSLRFLKCCYTKLPAQAIPCSLAWVRPVEEHWTSRAVLQFQKLCGLKPLVGVVDEYVDGILNIFLCDTSSNEDVYFHHVLRTEGHAIVCRENVPSKGFRDLNPLALYTKSSVTPEDIVLKELGYHSQQHYFNEDREISPQSKESDLYTLQDINDEKTFSHLGSVTSDEPLKDSKLNSLKIQDKSYEEDPKWSIPELKDLKEENEDEIPTGMPYLESVTIGDDIWDENWLPLQAKMGKESDAASHLFTSSLGGKKPYPSCKEIPQKDWCFSTPKDIWDDSWQPSGLVNGMKVEVQIPEGLGAQEKHIDTTRIQKQSNVKSASDSPALPKLEEFYISLIQSQQSAEGSQFEPSNIQTPPKQIQLSSTPTLVNSGSVEGSPESLENEDFSSSSAITVFKDTSQGAVDQLSLILSPEHQISQKFYIPRSTATAALGAAARLATSNSLLHWYPSVKKMET", "length": 1039, "header": "tr|G5E528-1|G5E528_BOVIN Computationally mapped isoform of Tudor domain-containing protein 5 OS=Bos taurus OX=9913 GN=TDRD5 PE=3 SV=3 CANONICAL=A0AAA9TUL2-1" }, "locus": { "chromosome": "16", "start_pos": 60894703, "end_pos": 60817250, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000003118.8", "url": "https://www.ensembl.org/id/ENSBTAT00000003118.8" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000003118.7", "url": "https://www.ensembl.org/id/ENSBTAP00000003118.7" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [ { "id": "bta:537634", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?bta:537634", "resource": "KEGG Pathway" } ], "orthologs": [], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 4, "go_terms": [ { "name": "cytoplasm", "id": "GO:0005737", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005737", "evidence": [ { "database": "UniProtKB", "id": "A0AAA9TUL2", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TUL2" } ], "pmid": "" }, { "name": "synapse", "id": "GO:0045202", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0045202", "evidence": [ { "database": "UniProtKB", "id": "A0AAA9TUL2", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TUL2" } ], "pmid": "" }, { "name": "pi-body", "id": "GO:0071546", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0071546", "evidence": [ { "database": "UniProtKB", "id": "A0AAA9TUL2", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TUL2" } ], "pmid": "" }, { "name": "chromatoid body", "id": "GO:0033391", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0033391", "evidence": [ { "database": "UniProtKB", "id": "A0AAA9TUL2", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TUL2" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 5, "go_terms": [ { "name": "spermatogenesis", "id": "GO:0007283", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007283", "evidence": [ { "database": "UniProtKB", "id": "A0AAA9TUL2", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TUL2" } ], "pmid": "" }, { "name": "germ cell development", "id": "GO:0007281", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007281", "evidence": [ { "database": "UniProtKB", "id": "A0AAA9TUL2", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TUL2" } ], "pmid": "" }, { "name": "P granule organization", "id": "GO:0030719", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030719", "evidence": [ { "database": "UniProtKB", "id": "A0AAA9TUL2", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TUL2" } ], "pmid": "" }, { "name": "spermatid development", "id": "GO:0007286", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007286", "evidence": [ { "database": "UniProtKB", "id": "A0AAA9TUL2", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TUL2" } ], "pmid": "" }, { "name": "transposable element silencing by piRNA-mediated DNA methylation", "id": "GO:0141196", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0141196", "evidence": [ { "database": "UniProtKB", "id": "A0AAA9TUL2", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TUL2" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 412, "end_pos": 414, "annotation": "n_glycosylation_sequon" }, { "start_pos": 592, "end_pos": 594, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A0AAA9TUL2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TUL2" }, { "id": "PS51644", "database": "PROSITE", "url": "https://prosite.expasy.org/PS51644" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "HTH OST-type", "eco_id": "ECO_0000259", "start_pos": 148, "end_pos": 221, "start_aa": "Ile", "end_aa": "Pro", "glycosite_overlap": [] }, { "evidence": [ { "id": "A0AAA9TUL2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TUL2" }, { "id": "PS50304", "database": "PROSITE", "url": "https://prosite.expasy.org/PS50304" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "Tudor", "eco_id": "ECO_0000259", "start_pos": 679, "end_pos": 738, "start_aa": "Phe", "end_aa": "Leu", "glycosite_overlap": [] } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 412, "end_pos": 414 }, { "start_pos": 592, "end_pos": 594 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": 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"https://www.ebi.ac.uk/interpro/entry/IPR016201", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR035914", "url": "https://www.ebi.ac.uk/interpro/entry/IPR035914", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR051568", "url": "https://www.ebi.ac.uk/interpro/entry/IPR051568", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR056732", "url": "https://www.ebi.ac.uk/interpro/entry/IPR056732", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR056737", "url": "https://www.ebi.ac.uk/interpro/entry/IPR056737", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR056863", "url": "https://www.ebi.ac.uk/interpro/entry/IPR056863", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "PTHR46376", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR46376", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR46376:SF3", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR46376:SF3", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00059", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00059", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF00431", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00431", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF01437", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF01437", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF23106", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF23106", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF24972", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF24972", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF24973", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF24973", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF24981", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF24981", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "A0A3S5ZP40", "url": "https://www.uniprot.org/uniprotkb/A0A3S5ZP40", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A3S5ZP40-1", "url": "https://www.uniprot.org/uniprotkb/A0A3S5ZP40-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0AAA9TUV1", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TUV1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0AAA9TUV1-1", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TUV1-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MIGARVPGQQRSTRPAWLKKRLAPGNQREQGASELLPRRGRAKRMNRTTPRELLDTKVEGGRENSLSPTRRVTEPPSGKRVPDDASPRAPPTHARTPWPRLSRRSGPALRIDRPSHRPHSPAPHGQAKLSRPCGVCVCVCVWVYVFTGHRLSPGKMVAAATEARLRRTVVTPAPTSRNGRRCRDWDATRAGRPGLRTGLRLPRRWRRLLLLLLPPLLLLPWAAEAAAAAASVSGSAAAEAKECDRPCVNGGRCNPGTGQCVCPAGWVGEQCQHCGGRFRLTGSSGFITDGPGNYKYKTKCTWLIEGQPNRIMRLRFNHFATECSWDHLYVYDGDSIYAPLVAAFSGLIVPERDGNETVPEVVATSGYALLHFFSDAAYNLTGFNITYNFDMCPNNCSGRGECKISNSSNTVQCECSENWKGEACDIPHCVNNCGFPHRGICNSSDVRGCSCFSEWQGPGCSVPVPANQSFWTREEYSDLKLPRASHKAVVNGNIMWVVGGYMFNHSDYNMVLAYDLASREWLALNRSVNSVVVRYGHSLALYQDKIYMYGGKIDSTGNVTNELRVFHIHNESWVLLSPKAKEQYAVVGHSAHIVTLKNGRVVMLVIFGHCPLYGYISSVQEYDLDKNTWSILHTQGALVQGGYGHSSVYDDRTKALYIHGGYKAFSANKYRLADDLYRYDVDTQMWTILKDSRFFRYLHTAVIVSGTMLVFGGNTHNDTSMSHGAKCFSSDFMAYDIDCDRWSVLPRPDLHHDVNRFGHSAVLYNRTMYVFGGFNSLLLSDILVFTSEQCEAHQSEAACLAAGPGVRCMWDTGSSQCVSWELAPEAQEKIKSECFSKRIFDHDRCDQLTDCYSCTANTNGCQWCNDHCVPTNHSCTEGQISIFKYDHCPKDNPMYYCNKKTSCRSCALDQNCQWEPRNQECIALPENICGIGWHLVGNSCLKITTAKETYDNAKLSCRNHNAFLASLTTQKKVEFVLKQLRIMQSSQSMSKFTLTPWVGLRKINVSYWCWEDMSPFTNSSLQWMPSEPSDAGFCGILSEPSTRGLKAATCINPLNGSVCERPANHSAKQCRTPCALRTACGECTSGSSECMWCSNMKQCVDSNAYVASFPFGQCMEWYTMSSCPPENCSGYCTCSHCLEQPGCGWCTDPSNTGKGKCIEGSYKGPVKMPSQGPTGNSYPQPLLNSSMCLEDSRYNWSFIHCPACQCNGHSKCINQSICEKCENLTTGKHCETCISGFYGDPTNGGKCQPCRCNGHASLCNTNTGKCFCTTKGVKGDECQLCEVENRYQGNPLKGTCYYTLLIDYQFTFSLSQEDDRYYTAINFVATPDEQNRDLDMFINASKNFNLNITWAASFSAGTQAGEEMPVVSKTNIKEYKDSFSNEKFDFRNHPNITFFVYVSNFTWPIKIQIAFSQHSNFMDLVQFFVTFFSCFLSLLLVAAVVWKIKQSCWASRRREQLLREMQQMASRPFASVNVALETDEEPPDLIGGSIKTVPKPIALEPCFGNKAAVLSVFVRLPRGLGGIPPPGQSGLAVASALVDISQQMPVVYKEKSGAVRNRKQQPPAQPGTCI", "length": 1570, "header": "tr|A0AAA9TUV1-1|A0AAA9TUV1_BOVIN Isoform 1 of Attractin OS=Bos taurus OX=9913 GN=ATRN PE=4 SV=1 CANONICAL=A0AAA9TUV1-1" }, "isoforms": [ { "isoform_ac": "A0A3S5ZP40-1", "url": "https://www.uniprot.org/uniprotkb/A0A3S5ZP40/entry", "sequence": { "sequence": 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"length": 1377, "header": "tr|A0A3S5ZP40-1|A0AAA9TUV1_BOVIN Computationally mapped isoform of Attractin OS=Bos taurus OX=9913 GN=ATRN PE=4 SV=2 CANONICAL=A0AAA9TUV1-1" }, "locus": { "chromosome": "13", "start_pos": 51731721, "end_pos": 51545555, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000039853.6", "url": "https://www.ensembl.org/id/ENSBTAT00000039853.6" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000039639.6", "url": "https://www.ensembl.org/id/ENSBTAP00000039639.6" } ] } }, { "isoform_ac": "A0AAA9TUV1-1", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TUV1/entry", "sequence": { "sequence": "MIGARVPGQQRSTRPAWLKKRLAPGNQREQGASELLPRRGRAKRMNRTTPRELLDTKVEGGRENSLSPTRRVTEPPSGKRVPDDASPRAPPTHARTPWPRLSRRSGPALRIDRPSHRPHSPAPHGQAKLSRPCGVCVCVCVWVYVFTGHRLSPGKMVAAATEARLRRTVVTPAPTSRNGRRCRDWDATRAGRPGLRTGLRLPRRWRRLLLLLLPPLLLLPWAAEAAAAAASVSGSAAAEAKECDRPCVNGGRCNPGTGQCVCPAGWVGEQCQHCGGRFRLTGSSGFITDGPGNYKYKTKCTWLIEGQPNRIMRLRFNHFATECSWDHLYVYDGDSIYAPLVAAFSGLIVPERDGNETVPEVVATSGYALLHFFSDAAYNLTGFNITYNFDMCPNNCSGRGECKISNSSNTVQCECSENWKGEACDIPHCVNNCGFPHRGICNSSDVRGCSCFSEWQGPGCSVPVPANQSFWTREEYSDLKLPRASHKAVVNGNIMWVVGGYMFNHSDYNMVLAYDLASREWLALNRSVNSVVVRYGHSLALYQDKIYMYGGKIDSTGNVTNELRVFHIHNESWVLLSPKAKEQYAVVGHSAHIVTLKNGRVVMLVIFGHCPLYGYISSVQEYDLDKNTWSILHTQGALVQGGYGHSSVYDDRTKALYIHGGYKAFSANKYRLADDLYRYDVDTQMWTILKDSRFFRYLHTAVIVSGTMLVFGGNTHNDTSMSHGAKCFSSDFMAYDIDCDRWSVLPRPDLHHDVNRFGHSAVLYNRTMYVFGGFNSLLLSDILVFTSEQCEAHQSEAACLAAGPGVRCMWDTGSSQCVSWELAPEAQEKIKSECFSKRIFDHDRCDQLTDCYSCTANTNGCQWCNDHCVPTNHSCTEGQISIFKYDHCPKDNPMYYCNKKTSCRSCALDQNCQWEPRNQECIALPENICGIGWHLVGNSCLKITTAKETYDNAKLSCRNHNAFLASLTTQKKVEFVLKQLRIMQSSQSMSKFTLTPWVGLRKINVSYWCWEDMSPFTNSSLQWMPSEPSDAGFCGILSEPSTRGLKAATCINPLNGSVCERPANHSAKQCRTPCALRTACGECTSGSSECMWCSNMKQCVDSNAYVASFPFGQCMEWYTMSSCPPENCSGYCTCSHCLEQPGCGWCTDPSNTGKGKCIEGSYKGPVKMPSQGPTGNSYPQPLLNSSMCLEDSRYNWSFIHCPACQCNGHSKCINQSICEKCENLTTGKHCETCISGFYGDPTNGGKCQPCRCNGHASLCNTNTGKCFCTTKGVKGDECQLCEVENRYQGNPLKGTCYYTLLIDYQFTFSLSQEDDRYYTAINFVATPDEQNRDLDMFINASKNFNLNITWAASFSAGTQAGEEMPVVSKTNIKEYKDSFSNEKFDFRNHPNITFFVYVSNFTWPIKIQIAFSQHSNFMDLVQFFVTFFSCFLSLLLVAAVVWKIKQSCWASRRREQLLREMQQMASRPFASVNVALETDEEPPDLIGGSIKTVPKPIALEPCFGNKAAVLSVFVRLPRGLGGIPPPGQSGLAVASALVDISQQMPVVYKEKSGAVRNRKQQPPAQPGTCI", "length": 1570, "header": "tr|A0AAA9TUV1-1|A0AAA9TUV1_BOVIN Isoform 1 of Attractin OS=Bos taurus OX=9913 GN=ATRN PE=4 SV=1 CANONICAL=A0AAA9TUV1-1" }, "locus": { "chromosome": "13", "start_pos": 51732186, "end_pos": 51545555, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000091435.1", "url": "https://www.ensembl.org/id/ENSBTAT00000091435.1" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000102138.1", "url": "https://www.ensembl.org/id/ENSBTAP00000102138.1" } ] } } ], "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "other", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 171, "start_aa": "Thr", "end_pos": 171, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr171", "evidence": [ { "id": "", "database": "GlyGen", "url": "https://data.glygen.org/" } ], "filter_code": "000000000000000010000.00000000001000.0.01000" } ], "phosphorylation": [], "glycation": [], "keywords": [ "glycoprotein", "glycoprotein_predicted" ], "publication": [], "pathway": [], "orthologs": [], "go_annotation": { "categories": [ { "name": "Molecular Function", "total": 3, "go_terms": [ { "name": "chromatin binding", "id": "GO:0003682", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003682", "evidence": [ { "database": "UniProtKB", "id": "A0AAA9TUV1", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TUV1" } ], "pmid": "" }, { "name": "carbohydrate binding", "id": "GO:0030246", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030246", "evidence": [ { "database": "UniProtKB", "id": "A0AAA9TUV1", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TUV1" } ], "pmid": "" }, { "name": "signaling receptor activity", "id": "GO:0038023", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0038023", "evidence": [ { "database": "UniProtKB", "id": 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"categories": [ "Protein" ] }, { "id": "A0AAA9RUR0-1", "url": "https://www.uniprot.org/uniprotkb/A0AAA9RUR0-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0AAA9RY00", "url": "https://www.uniprot.org/uniprotkb/A0AAA9RY00", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0AAA9RY00-1", "url": "https://www.uniprot.org/uniprotkb/A0AAA9RY00-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0AAA9SMG3", "url": "https://www.uniprot.org/uniprotkb/A0AAA9SMG3", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0AAA9SMG3-1", "url": "https://www.uniprot.org/uniprotkb/A0AAA9SMG3-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0AAA9SUD9", "url": "https://www.uniprot.org/uniprotkb/A0AAA9SUD9", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0AAA9SUD9-1", "url": "https://www.uniprot.org/uniprotkb/A0AAA9SUD9-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0AAA9TEN7", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TEN7", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0AAA9TEN7-1", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TEN7-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0AAA9TT37", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TT37", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0AAA9TT37-1", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TT37-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0AAA9TUS1", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TUS1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0AAA9TUS1-1", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TUS1-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "E1BD13", "url": "https://www.uniprot.org/uniprotkb/E1BD13", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "E1BD13-1", "url": "https://www.uniprot.org/uniprotkb/E1BD13-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MEAPEYLDLDEIDFSDDISYSVTSLKTIPELCRRCDSQNEDRSVSSSGWNCGVSTLITNTQKPTGIADVYSKFRPVKRVSPLKHQPETLENNESDDQKNQKAEYQKGNDPDPGPQPEELGPRAVEGSPQRKSTEPSTLLGELEHYDLDMDEILDVPYIKSSQQLASFTKATSEKRILGLCTSINGLSGKACPTGSAESSPSNMTPFCVLSPVKSPHLRKASSVVQDQQKLSPEESESSPPLVKSGSAYEPENQGKDFLHKTFSDPHSRKVDKAMAPDCQLRAFHLQSSATDPKLEEQIGGMNWTSSQGPEERNEYLKKVKSILNIVKEGQISLLPHLAADNLDKIHDESGNNLLHVAASQGHAECLQHLTSLMGEDCLNERNVEKLTPAGLAIKNGQLECVRWMVSETEAIAELSCSKDFPSLIHYAGCFGQEKILLWLLQFMQEQGISLDEVDQDGNSAVHVASQHGYLGCIQTLVEYGANVTMQNHAGEKPSQSAERHGHSLCSRYLVVVETCMSLASQVVKLTKQLKEQTTQRVTLQNQLQQLLEAQKSEGKSLLSSPSSPSSPACRKSQWKSPDAEDESVAKSKSGVQEGIQVLGSLSASSRARAKVKDEDSDKILRQLLGKDISENVCTQEKLSLEFQDAQTSSRHSKKIPLEKRELKLARLKQLMQRPLSEADTDSNNSEDPKGTPVRKVDRPRPQPIVESVEGVDSAESLHLMIKKHTLASGRRFPFSIKASKSLEGHSPSPTSESSEPDLESQCPGSGNTPSSQPSGEAPQPSPDSTAAQKVATSPKSALKSPSSKRRTSQNSKLRVTFEEPVVQMEQTSLELNGEKEREKGRTLQRTSAASESGDQLKRPFGTFRSIMETLSGNQNNNNNYQASNQLKTSTLPLTSLGRKVTDGKGNTGSSASKGKNKAA", "length": 919, "header": "tr|A0AAA9TT37-1|A0AAA9TT37_BOVIN Isoform 1 of Synphilin-1 OS=Bos taurus OX=9913 GN=SNCAIP PE=4 SV=1 CANONICAL=A0AAA9TT37-1" }, "isoforms": [ { "isoform_ac": "A0A3Q1LHI7-1", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1LHI7/entry", "sequence": { "sequence": "MEAPEYLDLDEIDFSDDISYSVTSLKTIPELCRRCDSQNEDRSVSSSGWNCGVSTLITNTQKPTGIADVYSKFRPVKRVSPLKHQPETLENNESDDQKNQKAEYQKGNDPDPGPQPEELGPRAVEGSPQRKSTEPSTLLGELEHYDLDMDEILDVPYIKSSQQLASFTKATSEKRILGLCTSINGLSGKACPTGSAESSPSNMTPFCVLSPVKSPHLRKASSVVQDQQKLSPEESESSPPLVKSGSAYEPENQGKDFLHKTFSDPHSRKVDKAMAPDCQLRAFHLQSSATDPKLEEQIGGMNWTSSQGPEERNEYLKKVKSILNIVKEGQISLLPHLAADNLDKIHDESGNNLLHVAASQGHAECLQHLTSLMGEDCLNERNVEKLTPAGLAIKNGQLECVRWMVSETEAIAELSCSKDFPSLIHYAGCFGQEKILLWLLQFMQEQGISLDEVDQDGNSAVHVASQHGYLGCIQTLVEYGANVTMQNHAGEKPSQSAERHGHSLCSRYLVVVETCMSLASQVVKLTKQLKEQTTQRVTLQNQLQQLLEAQKSEGKSLLSSPSSPSSPACRKSQWKSPDAEDESVAKSKSGVQEGIQVLGSLSASSRARAKVKDEDSDKILRQLLGKDISENVCTQEKLSLEFQDAQTSSRHSKKIPLEKRELKLARLKQLMQRPLSEADTDSNNSEDPKGTPVRKVDRPRPQPIVESVEGVDSAESLHLMIKKHTLASGRRFPFSIKASKSLEGHSPSPTSESSEPDLESQCPGSGNTPSSQPSGEAPQPSPDSTAAQKVATSPKSALKSPSSKRRTSQNSKLRVTFEEPVVQMEQTSLELNGEKEREKGRTLQRTSAASESGDQLKRPFGTFRSIMETLSGNQNNNNNYQASNQLKTSTLPLTSLGRKVTDGKGNTGSSASKGKNKAEMYGSCINLSSNTLIEEHLHNYARHDDISRKMKKSYSIKHVAEPESKELFL", "length": 969, "header": "tr|A0A3Q1LHI7-1|A0AAA9TT37_BOVIN Computationally mapped isoform of Synphilin-1 OS=Bos taurus OX=9913 GN=SNCAIP PE=4 SV=2 CANONICAL=A0AAA9TT37-1" }, "locus": { "chromosome": "7", "start_pos": 31458429, "end_pos": 31381351, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000078736.2", "url": "https://www.ensembl.org/id/ENSBTAT00000078736.2" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000058210.2", "url": "https://www.ensembl.org/id/ENSBTAP00000058210.2" } ] } }, { "isoform_ac": "A0A3Q1NHI3-1", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1NHI3/entry", "sequence": { "sequence": "MEAPEYLDLDEIDFSDDISYSVTSLKTIPELCRRCDSQNEDRSGGILYHRTTWEAHFWVVLTGKEQTHTVSSSGWNCGVSTLITNTQKPTGIADVYSKFRPVKRVSPLKHQPETLENNESDDQKNQKAEYQKGNDPDPGPQPEELGPRAVEGSPQRKSTEPSTLLGELEHYDLDMDEILDVPYIKSSQQLASFTKATSEKRILGLCTSINGLSGKACPTGSAESSPSNMTPFCVLSPVKSPHLRKASSVVQDQQKLSPEESESSPPLVKSGSAYEPENQGKDFLHKTFSDPHSRKVDKAMAPDCQLRAFHLQSSATDPKLEEQIGGMNWTSSQGPEERNEYLKKVKSILNIVKEGQISLLPHLAADNLDKIHDESGNNLLHVAASQGHAECLQHLTSLMGEDCLNERNVEKLTPAGLAIKNGQLECVRWMVSETEAIAELSCSKDFPSLIHYAGCFGQEKILLWLLQFMQEQGISLDEVDQDGNSAVHVASQHGYLGCIQTLVEYGANVTMQNHAGEKPSQSAERHGHSLCSRYLVVVETCMSLASQVVKLTKQLKEQTTQRVTLQNQLQQLLEAQKSEGKSLLSSPSSPSSPACRKSQWKSPDAEDESVAKSKSGVQEGIQVLGSLSASSRARAKVKDEDSDKILRQLLGKDISENVCTQEKLSLEFQDAQTSSRHSKKIPLEKRELKLARLKQLMQRPLSEADTDSNNSEDPKGTPVRKVDRPRPQPIVESVEGVDSAESLHLMIKKHTLASGRRFPFSIKASKSLEGHSPSPTSESSEPDLESQCPGSGNTPSSQPSGEAPQPSPDSTAAQKVATSPKSALKSPSSKRRTSQNSKLRVTFEEPVVQMEQTSLELNGEKEREKGRTLQRTSAASESGDQLKRPFGTFRSIMETLSGNQNNNNNYQASNQLKTSTLPLTSLGRKVTDGKGNTGSSASKGKNKAEMYGSCINLSSNTLIEEHLHNYARHDDISRKMKKSYSIKHVAEPESKELFL", "length": 995, "header": "tr|A0A3Q1NHI3-1|A0AAA9TT37_BOVIN Computationally mapped isoform of Synphilin-1 OS=Bos taurus OX=9913 GN=SNCAIP PE=4 SV=1 CANONICAL=A0AAA9TT37-1" }, "locus": { "chromosome": "7", "start_pos": 31458429, "end_pos": 31381351, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000083859.2", "url": "https://www.ensembl.org/id/ENSBTAT00000083859.2" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000071434.2", "url": "https://www.ensembl.org/id/ENSBTAP00000071434.2" } ] } }, { "isoform_ac": "A0AAA9RUR0-1", "url": "https://www.uniprot.org/uniprotkb/A0AAA9RUR0/entry", "sequence": { "sequence": "MEAPEYLDLDEIDFSDDISYSVTSLKTIPELCRRCDSQNEDRSGGILYHRTTWEAHFWVVLTGKEQTHTVSSSGWNCGVSTLITNTQKPTGIADVYSKFRPVKRVSPLKHQPETLENNESDDQKNQKAEYQKGNDPDPGPQPEELGPRAVEGSPQRKSTEPSTLLGELEHYDLDMDEILDVPYIKSSQQLASFTKATSEKRILGLCTSINGLSGKACPTGSAESSPSNMTPFCVLSPVKSPHLRKASSVVQDQQKLSPEESESSPPLVKSGSAYEPENQGKDFLHKTFSDPHSRKVDKAMAPDCQLRAFHLQSSATDPKLEEQIGGMNWTSSQGPEERNEYLKKVKSILNIVKEGQISLLPHLAADNLDKIHDESGNNLLHVAASQGHAECLQHLTSLMGEDCLNERNVEKLTPAGLAIKNGQLECVRWMVSETEAIAELSCSKDFPSLIHYAGCFGQEKILLWLLQFMQEQGISLDEVDQDGNSAVHVASQHGYLGCIQTLVEYGANVTMQNHAGEKPSQSAERHGHSLCSRYLVVVETCMSLASQVVKLTKQLKEQTTQRVTLQNQLQQLLEAQKSEGKSLLSSPSSPSSPACRKSQWKSPDAEDESVAKSKSGVQEGIQVLGSLSASSRARAKVKDEDSDKILRQLLGKDISENVCTQEKLSLEFQDAQTSSRHSKKIPLEKRELKLARLKQLMQRPLSEADTDSNNSEDPKGTPVRKVDRPRPQPIVESVEGVDSAESLHLMIKKHTLASGRRFPFSIKASKSLEGHSPSPTSESSEPDLESQCPGSGNTPSSQPSGEAPQPSPDSTAAQKVATSPKSALKSPSSKRRTSQNSKLRVTFEEPVVQMEQTSLELNGEKEREKGRTLQRTSAASESGDQLKRPFGTFRSIMETLSGNQNNNNNYQASNQLKTSTLPLTSLGRKVTDGKGNTGSSASKGKNKALRKAKLVPPNTRLYGLNMSKLTLLE", "length": 969, "header": "tr|A0AAA9RUR0-1|A0AAA9TT37_BOVIN Computationally mapped isoform of Synphilin-1 OS=Bos taurus OX=9913 GN=SNCAIP PE=4 SV=1 CANONICAL=A0AAA9TT37-1" }, "locus": { "chromosome": "7", "start_pos": 31458429, "end_pos": 31393439, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000091742.1", "url": "https://www.ensembl.org/id/ENSBTAT00000091742.1" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000074678.1", "url": "https://www.ensembl.org/id/ENSBTAP00000074678.1" } ] } }, { "isoform_ac": "A0AAA9RY00-1", "url": "https://www.uniprot.org/uniprotkb/A0AAA9RY00/entry", "sequence": { "sequence": "MKLTSVMTSLIQSHHSRPSRNCAEDVIRKMKTDQALLQISSVVEKEANFKFRCLQTHPEQTSNAQGGILYHRTTWEAHFWVVLTGKEQTHTVSSSGWNCGVSTLITNTQKPTGIADVYSKFRPVKRVSPLKHQPETLENNESDDQKNQKAEYQKGNDPDPGPQPEELGPRAVEGSPQRKSTEPSTLLGELEHYDLDMDEILDVPYIKSSQQLASFTKATSEKRILGLCTSINGLSGKACPTGSAESSPSNMTPFCVLSPVKSPHLRKASSVVQDQQKLSPEESESSPPLVKSGSAYEPENQGKDFLHKTFSDPHSRKVDKAMAPDCQLRAFHLQSSATDPKLEEQIGGMNWTSSQGPEERNEYLKKVKSILNIVKEGQISLLPHLAADNLDKIHDESGNNLLHVAASQGHAECLQHLTSLMGEDCLNERNVEKLTPAGLAIKNGQLECVRWMVSETEAIAELSCSKDFPSLIHYAGCFGQEKILLWLLQFMQEQGISLDEVDQDGNSAVHVASQHGYLGCIQTLVEYGANVTMQNHAGEKPSQSAERHGHSLCSRYLVVVETCMSLASQVVKLTKQLKEQTTQRVTLQNQLQQLLEAQKSEGKSLLSSPSSPSSPACRKSQWKSPDAEDESVAKSKSGVQEGIQVLGSLSASSRARAKVKDEDSDKILRQLLGKDISENVCTQEKLSLEFQDAQTSSRHSKKIPLEKRELKLARLKQLMQRPLSEADTDSNNSEDPKGTPVRKVDRPRPQPIVESVEGVDSAESLHLMIKKHTLASGRRFPFSIKASKSLEGHSPSPTSESSEPDLESQCPGSGNTPSSQPSGEAPQPSPDSTAAQKVATSPKSALKSPSSKRRTSQNSKLRVTFEEPVVQMEQTSLELNGEKEREKGRTLQRTSAASESGDQLKRPFGTFRSIMETLSGNQNNNNNYQASNQLKTSTLPLTSLGRKVTDGKGNTGSSASKGKNKAEMYGSCINLSSNTLIEEHLHNYAR", "length": 990, "header": "tr|A0AAA9RY00-1|A0AAA9TT37_BOVIN Computationally mapped isoform of Synphilin-1 OS=Bos taurus OX=9913 GN=SNCAIP PE=4 SV=1 CANONICAL=A0AAA9TT37-1" }, "locus": { "chromosome": "7", "start_pos": 31458401, "end_pos": 31393172, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000131238.1", "url": "https://www.ensembl.org/id/ENSBTAT00000131238.1" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000077468.1", "url": "https://www.ensembl.org/id/ENSBTAP00000077468.1" } ] } }, { "isoform_ac": "A0AAA9SMG3-1", "url": "https://www.uniprot.org/uniprotkb/A0AAA9SMG3/entry", "sequence": { "sequence": "MLIYIRASFLKYSVTSLKTIPELCRRCDSQNEDRSVSSSGWNCGVSTLITNTQKPTGIADVYSKFRPVKRVSPLKHQPETLENNESDDQKNQKAEYQKGNDPDPGPQPEELGPRAVEGSPQRKSTEPSTLLGELEHYDLDMDEILDVPYIKSSQQLASFTKATSEKRILGLCTSINGLSGKACPTGSAESSPSNMTPFCVLSPVKSPHLRKASSVVQDQQKLSPEESESSPPLVKSGSAYEPENQGKDFLHKTFSDPHSRKVDKAMAPDCQLRAFHLQSSATDPKLEEQIGGMNWTSSQGPEERNEYLKKVKSILNIVKEGQISLLPHLAADNLDKIHDESGNNLLHVAASQGHAECLQHLTSLMGEDCLNERNVEKLTPAGLAIKNGQLECVRWMVSETEAIAELSCSKDFPSLIHYAGCFGQEKILLWLLQFMQEQGISLDEVDQDGNSAVHVASQHGYLGCIQTLVEYGANVTMQNHAGEKPSQSAERHGHSLCSRYLVVVETCMSLASQVVKLTKQLKEQTTQRVTLQNQLQQLLEAQKSEGKSLLSSPSSPSSPACRKSQWKSPDAEDESVAKSKSGVQEGIQVLGSLSASSRARAKVKDEDSDKILRQLLGKDISENVCTQEKLSLEFQDAQTSSRHSKKIPLEKRELKLARLKQLMQRPLSEADTDSNNSEDPKGTPVRKVDRPRPQPIVESVEGVDSAESLHLMIKKHTLASGRRFPFSIKASKSLEGHSPSPTSESSEPDLESQCPGSGNTPSSQPSGEAPQPSPDSTAAQKVATSPKSALKSPSSKRRTSQNSKLRVTFEEPVVQMEQTSLELNGEKEREKGRTLQRTSAASESGDQLKRPFGTFRSIMETLSGNQNNNNNYQASNQLKTSTLPLTSLGRKVTDGKGNTGSSASKGKNKAEMYGSCINLSSNTLIEEHLHNYARHDDISRKMKKSYSIKHVAEPESKELFL", "length": 961, "header": "tr|A0AAA9SMG3-1|A0AAA9TT37_BOVIN Computationally mapped isoform of Synphilin-1 OS=Bos taurus OX=9913 GN=SNCAIP PE=4 SV=1 CANONICAL=A0AAA9TT37-1" }, "locus": { "chromosome": "7", "start_pos": 31443784, "end_pos": 31381351, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000097822.1", "url": "https://www.ensembl.org/id/ENSBTAT00000097822.1" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000083947.1", "url": "https://www.ensembl.org/id/ENSBTAP00000083947.1" } ] } }, { "isoform_ac": "A0AAA9SUD9-1", "url": "https://www.uniprot.org/uniprotkb/A0AAA9SUD9/entry", "sequence": { "sequence": "MEAPEYLDLDEIDFSDDISYSVTSLKTIPELCRRCDSQNEDRSVSSSGWNCGVSTLITNTQKPTGIADVYSKFRPVKRVSPLKHQPETLENNESDDQKNQKAEYQKGNDPDPGPQPEELGPRAVEGSPQRKSTEPSTLLGELEHYDLDMDEILDVPYIKSSQQLASFTKATSEKRILGLCTSINGLSGKACPTGSAESSPSNMTPFCVLSPVKSPHLRKASSVVQDQQKLSPEESESSPPLVKSGSAYEPENQGKDFLHKTFSDPHSRKVDKAMAPDCQLRAFHLQSSATDPKLEEQIGGMNWTSSQGPEERNEYLKKVKSILNIVKEGQISLLGHAECLQHLTSLMGEDCLNERNVEKLTPAGLAIKNGQLECVRWMVSETEAIAELSCSKDFPSLIHYAGCFGQEKILLWLLQFMQEQGISLDEVDQDGNSAVHVASQHGYLGCIQTLVEYGANVTMQNHAGEKPSQSAERHGHSLCSRYLVVVETCMSLASQVVKLTKQLKEQTTQRVTLQNQLQQLLEAQKSEGKSLLSSPSSPSSPACRKSQWKSPDAEDESVAKSKSGVQEGIQVLGSLSASSRARAKVKDEDSDKILRQLLGKDISENVCTQEKLSLEFQDAQTSSRHSKKIPLEKRELKLARLKQLMQRPLSEADTDSNNSEDPKGTPVRKVDRPRPQPIVESVEGVDSAESLHLMIKKHTLASGRRFPFSIKASKSLEGHSPSPTSESSEPDLESQCPGSGNTPSSQPSGEAPQPSPDSTAAQKVATSPKSALKSPSSKRRTSQNSKLRVTFEEPVVQMEQTSLELNGEKEREKGRTLQRTSAASESGDQLKRPFGTFRSIMETLSGNQNNNNNYQASNQLKTSTLPLTSLGRKVTDGKGNTGSSASKGKNKAA", "length": 893, "header": "tr|A0AAA9SUD9-1|A0AAA9TT37_BOVIN Computationally mapped isoform of Synphilin-1 OS=Bos taurus OX=9913 GN=SNCAIP PE=4 SV=1 CANONICAL=A0AAA9TT37-1" }, "locus": { "chromosome": "7", "start_pos": 31458429, "end_pos": 31381430, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000114036.1", "url": "https://www.ensembl.org/id/ENSBTAT00000114036.1" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000087626.1", "url": "https://www.ensembl.org/id/ENSBTAP00000087626.1" } ] } }, { "isoform_ac": "A0AAA9TEN7-1", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TEN7/entry", "sequence": { "sequence": "MEAPEYLDLDEIDFSDDISYSVTSLKTIPELCRRCDSQNEDRSGGILYHRTTWEAHFWVVLTGKEQTHTVSSSGWNCGVSTLITNTQKPTGIADVYSKFRPVKRVSPLKHQPETLENNESDDQKNQKAEYQKGNDPDPGPQPEELGPRAVEGSPQRKSTEPSTLLGELEHYDLDMDEILDVPYIKSSQQLASFTKATSEKRILGLCTSINGLSGKACPTGSAESSPSNMTPFCVLSPVKSPHLRKASSVVQDQQKLSPEESESSPPLVKSGSAYEPENQGKDFLHKTFSDPHSRKVDKAMAPDCQLRAFHLQSSATDPKLEEQIGGMNWTSSQGPEERNEYLKKVKSILNIVKEGQISLLPHLAADNLDKIHDESGNNLLHVAASQGHAECLQHLTSLMGEDCLNERNVEKLTPAGLAIKNGQLECVRWMVSETEAIAELSCSKDFPSLIHYAGCFGQEKILLWLLQFMQEQGISLDEVDQDGNSAVHVASQHGYLGCIQTLVEYGANVTMQNHAGEKPSQSAERHGHSLCSRYLVVVETCMSLASQVVKLTKQLKEQTTQRVTLQNQLQQLLEAQKSEGKSLLSSPSSPSSPACRKSQWKSPDAEDESVAKSKSGVQEGIQVLGSLSASSRARAKVKDEDSDKILRQLLGKDISENVCTQEKLSLEFQDAQTSSRHSKKIPLEKRELKLARLKQLMQRPLSEADTDSNNSEDPKGTPVRKVDRPRPQPIVESVEGVDSAESLHLMIKKHTLASGRRFPFSIKASKSLEGHSPSPTSESSEPDLESQCPGSGNTPSSQPSGEAPQPSPDSTAAQKVATSPKSALKSPSSKRRTSQNSKLRVTFEEPVVQMEQTSLELNGEKEREKGRTLQRTSAASESGDQLKRPFGTFRSIMETLSGNQNNNNNYQASNQLKTSTLPLTSLGRKVTDGKGNTGSSASKGKNKAA", "length": 945, "header": "tr|A0AAA9TEN7-1|A0AAA9TT37_BOVIN Computationally mapped isoform of Synphilin-1 OS=Bos taurus OX=9913 GN=SNCAIP PE=4 SV=1 CANONICAL=A0AAA9TT37-1" }, "locus": { "chromosome": "7", "start_pos": 31458429, "end_pos": 31381430, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000101503.1", "url": "https://www.ensembl.org/id/ENSBTAT00000101503.1" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000097068.1", "url": "https://www.ensembl.org/id/ENSBTAP00000097068.1" } ] } }, { "isoform_ac": "A0AAA9TT37-1", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TT37/entry", "sequence": { "sequence": "MEAPEYLDLDEIDFSDDISYSVTSLKTIPELCRRCDSQNEDRSVSSSGWNCGVSTLITNTQKPTGIADVYSKFRPVKRVSPLKHQPETLENNESDDQKNQKAEYQKGNDPDPGPQPEELGPRAVEGSPQRKSTEPSTLLGELEHYDLDMDEILDVPYIKSSQQLASFTKATSEKRILGLCTSINGLSGKACPTGSAESSPSNMTPFCVLSPVKSPHLRKASSVVQDQQKLSPEESESSPPLVKSGSAYEPENQGKDFLHKTFSDPHSRKVDKAMAPDCQLRAFHLQSSATDPKLEEQIGGMNWTSSQGPEERNEYLKKVKSILNIVKEGQISLLPHLAADNLDKIHDESGNNLLHVAASQGHAECLQHLTSLMGEDCLNERNVEKLTPAGLAIKNGQLECVRWMVSETEAIAELSCSKDFPSLIHYAGCFGQEKILLWLLQFMQEQGISLDEVDQDGNSAVHVASQHGYLGCIQTLVEYGANVTMQNHAGEKPSQSAERHGHSLCSRYLVVVETCMSLASQVVKLTKQLKEQTTQRVTLQNQLQQLLEAQKSEGKSLLSSPSSPSSPACRKSQWKSPDAEDESVAKSKSGVQEGIQVLGSLSASSRARAKVKDEDSDKILRQLLGKDISENVCTQEKLSLEFQDAQTSSRHSKKIPLEKRELKLARLKQLMQRPLSEADTDSNNSEDPKGTPVRKVDRPRPQPIVESVEGVDSAESLHLMIKKHTLASGRRFPFSIKASKSLEGHSPSPTSESSEPDLESQCPGSGNTPSSQPSGEAPQPSPDSTAAQKVATSPKSALKSPSSKRRTSQNSKLRVTFEEPVVQMEQTSLELNGEKEREKGRTLQRTSAASESGDQLKRPFGTFRSIMETLSGNQNNNNNYQASNQLKTSTLPLTSLGRKVTDGKGNTGSSASKGKNKAA", "length": 919, "header": "tr|A0AAA9TT37-1|A0AAA9TT37_BOVIN Isoform 1 of Synphilin-1 OS=Bos taurus OX=9913 GN=SNCAIP PE=4 SV=1 CANONICAL=A0AAA9TT37-1" }, "locus": { "chromosome": "7", "start_pos": 31458429, "end_pos": 31381430, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000109906.1", "url": "https://www.ensembl.org/id/ENSBTAT00000109906.1" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000099684.1", "url": "https://www.ensembl.org/id/ENSBTAP00000099684.1" } ] } }, { "isoform_ac": "A0AAA9TUS1-1", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TUS1/entry", "sequence": { "sequence": "MKLTSVMTSLIQSHHSRPSRNCAEDVIRKMKTDQALLQISSVVEKEANFKFRCLQTHPEQTSNAQVSSSGWNCGVSTLITNTQKPTGIADVYSKFRPVKRVSPLKHQPETLENNESDDQKNQKAEYQKGNDPDPGPQPEELGPRAVEGSPQRKSTEPSTLLGELEHYDLDMDEILDVPYIKSSQQLASFTKATSEKRILGLCTSINGLSGKACPTGSAESSPSNMTPFCVLSPVKSPHLRKASSVVQDQQKLSPEESESSPPLVKSGSAYEPENQGKDFLHKTFSDPHSRKVDKAMAPDCQLRAFHLQSSATDPKLEEQIGGMNWTSSQGPEERNEYLKKVKSILNIVKEGQISLLPHLAADNLDKIHDESGNNLLHVAASQGHAECLQHLTSLMGEDCLNERNVEKLTPAGLAIKNGQLECVRWMVSETEAIAELSCSKDFPSLIHYAGCFGQEKILLWLLQFMQEQGISLDEVDQDGNSAVHVASQHGYLGCIQTLVEYGANVTMQNHAGEKPSQSAERHGHSLCSRYLVVVETCMSLASQVVKLTKQLKEQTTQRVTLQNQLQQLLEAQKSEGKSLLSSPSSPSSPACRKSQWKSPDAEDESVAKSKSGVQEGIQVLGSLSASSRARAKVKDEDSDKILRQLLGKDISENVCTQEKLSLEFQDAQTSSRHSKKIPLEKRELKLARLKQLMQRPLSEADTDSNNSEDPKGTPVRKVDRPRPQPIVESVEGVDSAESLHLMIKKHTLASGRRFPFSIKASKSLEGHSPSPTSESSEPDLESQCPGSGNTPSSQPSGEAPQPSPDSTAAQKVATSPKSALKSPSSKRRTSQNSKLRVTFEEPVVQMEQTSLELNGEKEREKGRTLQRTSAASESGDQLKRPFGTFRSIMETLSGNQNNNNNYQASNQLKTSTLPLTSLGRKVTDGKGNTGSSASKGKNKAEMYGSCINLSSNTLIEEHLHNYARHDDISRKMKKSYSIKHVAEPESKELFL", "length": 991, "header": "tr|A0AAA9TUS1-1|A0AAA9TUS1_BOVIN Computationally mapped isoform of Synphilin-1 OS=Bos taurus OX=9913 GN=SNCAIP PE=4 SV=1 CANONICAL=A0AAA9TT37-1" }, "locus": { "chromosome": "7", "start_pos": 31458401, "end_pos": 31381351, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000118899.1", "url": "https://www.ensembl.org/id/ENSBTAT00000118899.1" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000100330.1", "url": "https://www.ensembl.org/id/ENSBTAP00000100330.1" } ] } }, { "isoform_ac": "E1BD13-1", "url": "https://www.uniprot.org/uniprotkb/E1BD13/entry", "sequence": { "sequence": "MEAPEYLDLDEIDFSDDISDNRNQGNTIRLGLRSRHRTETGFRSLRAKITVMATLGAGHCPENYSVTSLKTIPELCRRCDSQNEDRSVSSSGWNCGVSTLITNTQKPTGIADVYSKFRPVKRVSPLKHQPETLENNESDDQKNQKAEYQKGNDPDPGPQPEELGPRAVEGSPQRKSTEPSTLLGELEHYDLDMDEILDVPYIKSSQQLASFTKATSEKRILGLCTSINGLSGKACPTGSAESSPSNMTPFCVLSPVKSPHLRKASSVVQDQQKLSPEESESSPPLVKSGSAYEPENQGKDFLHKTFSDPHSRKVDKAMAPDCQLRAFHLQSSATDPKLEEQIGGMNWTSSQGPEERNEYLKKVKSILNIVKEGQISLLPHLAADNLDKIHDESGNNLLHVAASQGHAECLQHLTSLMGEDCLNERNVEKLTPAGLAIKNGQLECVRWMVSETEAIAELSCSKDFPSLIHYAGCFGQEKILLWLLQFMQEQGISLDEVDQDGNSAVHVASQHGYLGCIQTLVEYGANVTMQNHAGEKPSQSAERHGHSLCSRYLVVVETCMSLASQVVKLTKQLKEQTTQRVTLQNQLQQLLEAQKSEGKSLLSSPSSPSSPACRKSQWKSPDAEDESVAKSKSGVQEGIQVLGSLSASSRARAKVKDEDSDKILRQLLGKDISENVCTQEKLSLEFQDAQTSSRHSKKIPLEKRELKLARLKQLMQRPLSEADTDSNNSEDPKGTPVRKVDRPRPQPIVESVEGVDSAESLHLMIKKHTLASGRRFPFSIKASKSLEGHSPSPTSESSEPDLESQCPGSGNTPSSQPSGEAPQPSPDSTAAQKVATSPKSALKSPSSKRRTSQNSKLRVTFEEPVVQMEQTSLELNGEKEREKGRTLQRTSAASESGDQLKRPFGTFRSIMETLSGNQNNNNNYQASNQLKTSTLPLTSLGRKVTDGKGNTGSSASKGKNKAEMYGSCINLSSNTLIEEHLHNYARHDDISRKMKKSYSIKHVAEPESKELFL", "length": 1013, "header": "tr|E1BD13-1|E1BD13_BOVIN Computationally mapped isoform of Synphilin-1 OS=Bos taurus OX=9913 GN=SNCAIP PE=4 SV=4 CANONICAL=A0AAA9TT37-1" }, "locus": { "chromosome": "7", "start_pos": 31458429, "end_pos": 31381351, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000029292.7", "url": "https://www.ensembl.org/id/ENSBTAT00000029292.7" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000029292.7", "url": "https://www.ensembl.org/id/ENSBTAP00000029292.7" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [ { "id": "bta:540156", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?bta:540156", "resource": "KEGG Pathway" } ], "orthologs": [ { "uniprot_canonical_ac": "A0A8V0X1S5-1", "protein_name": "Synuclein alpha interacting protein", "gene_name": "SNCAIP", "tax_id": 9031, "organism": "Gallus gallus", "sequence": { "sequence": "MEAPEYLDLDEIDFSDDISYSITSLKTIPELCRRCDSQNEDRSVSSSSWNCGGSALIGNAQKPTGIADACNKFRPVKRVSPLKHQPESCENNESDDQKNQKGEYQKGSESQPAPPNDDQSPGEGENLKSKNIEPTVLLGELEHYDLDMDEILDVPYIKSNQQLVPFTKVAPEKKTFGVSSTVNGVSGKTCSTESTEPAGVTQFCVLSPVKGSQLRKTQPIVLDQHKHLTEELELSQPLAKCSSVHETEAQGKGFLCRTFVGPQAHKTEKTMPNCHLRTFHLQTTVAESKQLEELNMSWSSAGGPEERSEEVKKFKSILNIVKEGQISLLPHLAADNLDKIHDECDNNLLHVAASKGHAECLQHLTSLMGEDCLNERNIEQLTPAGLAIKNGQLECVRWMVSETEAIAELSCSKDHPSLIHYAGCYGQEKILLWLLQFMQEQGISLDEVDQDGNTAVHIAAQHGYLGCIQTLVEYGANVTMQNHVGEKPSQSAERHGHTMCSRYLVVVETCMSLASQVVKLTKQLKEQTVERVTLQNQLQQLLEAQRPEGKSLPTSTSSPSSPASGKPQWKPTEADELSPPKSKLNAQDGIQILGSLGTSSRTRAKIKDEDSDKILRQLLGKEISENVCMQEKLTLEFQDAHASSKNVKKILPEKRELKLARLRQLMQRSLSESDTDSANSEDHKNTPVKRTDKLRPQPIVESVESAESLHLMIKKHASAAGRRFPFGTRASKSVDGHSPSPTSESSDPDNEAQYQSGTVPQSQFCGDSSPSSTDGAAAQKVATSPKSALKSPSSKRRTSQNLKLRVTFEEPVVQVELAEAELNEEKDKGKALPRAPASTGEPSGDQLKRPFGTFRSIMETLSGNQNNNNNCQTANLIKTSSTLPFSSLGRKAGDSKGNPAALTKGRNKPGPCFSYTNLSSSTLNEEHLCNYAWHDNISRKSQKSYSQKSSEETELQEFFL", "length": 960 }, "evidence": [ { "id": "A0AAA9TT37", "url": "https://omabrowser.org/oma/group/A0AAA9TT37/", "database": "OMA" } ], "glygen_name": "Chicken", "common_name": "Chicken" }, { "uniprot_canonical_ac": "A0ABK0LAF0-1", "protein_name": "Synphilin-1", "gene_name": "Sncaip", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MEAPEYLDLDEIDFSDDISYSVTSLKTIPALCRRCDSQNEDRPVSSSSWNCGVSTLITNPQKPTGIADVYSKFRPVKRVSPLKHQPETLESNESDDQKNNTVEYQKGGETDQGPQPEELSPEDGVGGLPGKGSEPSQALGELEHYDLDMDEILDVPYIKSSQQLAPLTKVTSEKRILGLCTTVNGLSAKTCPIVSAETSTPNMAPLCVLSPVKSPHLRKVPSVLRDQHKLPAEESENSPAPGKCGPAFESENHSKDFLNKVFSDPHSRKAEKSGPDCKLRPFRLQTSAAGAKPEEQVNGVSWASAQGAEERTEYLQKVRSILNIVNEGQISLLPHLAADNLDKIHDENGNNLLHVAASKGHAECLQHLTSLMGEDCLNERNAEQLTPAGLAIKNGQLECVRWMVSETEAIAELSCSKDFPSLIHYAGCYGQEKILLWLLQFMQEQGISLDEVDQEGNSAVHVASQHGYLGCIQTLVEYGANVTMQNHAGEKPSQSAERHGHTLCSRYLVVVETCMSLASQVVKLTKQLKEQTVERVTLQSQLQQLLEAQKSEGKSLPSSPSSPSSPASRKSQWKILDADDESTGKSKLGTQEGIQVLGNLSSRARTKGKDEDSDKILRQLLGKEISENVCTQEKLSLEFQDAQVSSRNSKKIPLEKRELKLARLRQLMQRSLSESDTDSNNSEDPKNTPVKRVDRPRPQPIVESVENMDSAESLHLMIKKHSVASGRRFPFGMKASKSLDGHSPSPTSESSEPDLDSHCPSLGMTPPTQPSTEATQCSPDSATAQKVATSPKSALKSPSSKRRTSQNSKLRVTFEEPVVQMEQTSLELNGEKDKERGRAPQRTSESGEQMKRPFGTFRSIMESLSGNQNNNNNYQPASQLKTCTLPLTSLGRKTADAKGNPVSPASKGKNKAA", "length": 913 }, "evidence": [ { "id": "A0AAA9TT37", "url": "https://omabrowser.org/oma/group/A0AAA9TT37/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "Q99ME3-1", "protein_name": "Synphilin-1", "gene_name": "Sncaip", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MEAPEYLDLDEIDFSDDISYSVTSLKTIPALCRRCDSQNEDRSVSSSGWNCGVSTLITNPQKPTGIADVYSKFRPVKRVSPLKHQPETLENNENEDQKNNTVEYQKGGETDQGPQPEELSPEDGVGGLPGKGSEPSQALGELEHYDLDMDEILDVPYIKSSQQLAPLTKVTSEKRILGLCTTINGLSAKTCPIASTENSTPNMTPFCVLSPVKSPHLRKAPTALRDQHKLSTEDSESSPALGKCGPAYESENHSKDFLNKVFSDPHSRKIEKSGPDCKLRSFHLQSSAAGAKTEEPINGMNWTNTQGTEERTEYLKKVRSILNIVNEGQISLLPHLAADNLDKIHDENGNNLLHIAASKGHAECLQHLTSLMGEDCLNERNTEQLTPAGLAIKNGQLECVRWMVSETEAIAELSCSKDFPSLIHYAGCYGQEKILLWLLQFMQEQGISLDEVDREGNSAVHVASQHGYLGCIQTLVEYGANVTMQNHAGEKPSQSAERHGHTLCSRYLVVVETCMSLASQVVKLTKQLKEQTVERVTLQSQLQQLLEAQKSEGKSLPSSPSSPSSPASTKSQWKALDTDEESTGKSKVGAQEGIQVLGSLSVSSRARTKGKDEDSDKILRQLLGKEISENVCTQEKLSLEFQDAQASSRNSKKIPLEKRELKLARLRQLMQRSLSESDTDSNNSEDPKNTPVKRADRPRPQPIVESVENVDSAESLHLMIKKHSLASGRRFPFGMKASKSLDGHSPSPTSESSEPDLDSHGPGLGMTPPTQPSTEATQSSPDSTAAQKVATSPKSALKSPSSKRRTSQNSKLRVTFEEPVVQMEQTGLELNGEKDKDKGRAPQRTSESGEQMKRPFGTFRSIMESLSGNQNNNNNYQPASQLKTCTLPLTSLGRKTADAKGNPVSPASKGKNKAAMYSSCIHLPSNALVEEHLRDYARHNDIKRNATKTYHMKHTAEPEPRE", "length": 962 }, "evidence": [ { "id": "A0AAA9TT37", "url": "https://omabrowser.org/oma/group/A0AAA9TT37/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q9Y6H5-1", "protein_name": "Synphilin-1", "gene_name": "SNCAIP", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MEAPEYLDLDEIDFSDDISYSVTSLKTIPELCRRCDTQNEDRSVSSSSWNCGISTLITNTQKPTGIADVYSKFRPVKRVSPLKHQPETLENNESDDQKNQKVVEYQKGGESDLGPQPQELGPGDGVGGPPGKSSEPSTSLGELEHYDLDMDEILDVPYIKSSQQLASFTKVTSEKRILGLCTTINGLSGKACSTGSSESSSSNMAPFCVLSPVKSPHLRKASAVIHDQHKLSTEETEISPPLVKCGSAYEPENQSKDFLNKTFSDPHGRKVEKTTPDCQLRAFHLQSSAAESKPEEQVSGLNRTSSQGPEERSEYLKKVKSILNIVKEGQISLLPHLAADNLDKIHDENGNNLLHIAASQGHAECLQHLTSLMGEDCLNERNTEKLTPAGLAIKNGQLECVRWMVSETEAIAELSCSKDFPSLIHYAGCYGQEKILLWLLQFMQEQGISLDEVDQDGNSAVHVASQHGYLGCIQTLVEYGANVTMQNHAGEKPSQSAERQGHTLCSRYLVVVETCMSLASQVVKLTKQLKEQTVERVTLQNQLQQFLEAQKSEGKSLPSSPSSPSSPASRKSQWKSPDADDDSVAKSKPGVQEGIQVLGSLSASSRARPKAKDEDSDKILRQLLGKEISENVCTQEKLSLEFQDAQASSRNSKKIPLEKRELKLARLRQLMQRSLSESDTDSNNSEDPKTTPVRKADRPRPQPIVESVESMDSAESLHLMIKKHTLASGGRRFPFSIKASKSLDGHSPSPTSESSEPDLESQYPGSGSIPPNQPSGDPQQPSPDSTAAQKVATSPKSALKSPSSKRRTSQNLKLRVTFEEPVVQMEQPSLELNGEKDKDKGRTLQRTSTSNESGDQLKRPFGAFRSIMETLSGNQNNNNNYQAANQLKTSTLPLTSLGRKTDAKGNPASSASKGKNKAA", "length": 919 }, "evidence": [ { "id": "A0AAA9TT37", "url": "https://omabrowser.org/oma/group/A0AAA9TT37/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" } ], "go_annotation": { "categories": [ { "name": "Molecular Function", "total": 1, "go_terms": [ { "name": "ubiquitin protein ligase binding", "id": "GO:0031625", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0031625", "evidence": [ { "database": "UniProtKB", "id": "A0AAA9TT37", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TT37" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 1, "go_terms": [ { "name": "cytoplasmic ribonucleoprotein granule", "id": "GO:0036464", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0036464", "evidence": [ { "database": "UniProtKB", "id": "A0AAA9TT37", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TT37" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 1, "go_terms": [ { "name": "regulation of inclusion body assembly", "id": "GO:0090083", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0090083", "evidence": [ { "database": "UniProtKB", "id": "A0AAA9TT37", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TT37" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 202, "end_pos": 204, "annotation": "n_glycosylation_sequon" }, { "start_pos": 302, "end_pos": 304, "annotation": "n_glycosylation_sequon" }, { "start_pos": 482, "end_pos": 484, "annotation": "n_glycosylation_sequon" }, { "start_pos": 683, "end_pos": 685, "annotation": "n_glycosylation_sequon" }, { "start_pos": 92, "end_pos": 94, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A0AAA9TT37", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TT37" }, { "id": "PF16700", "database": "Pfam", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF16700" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "Synphilin-1 alpha-Synuclein-binding", "eco_id": "ECO_0000259", "start_pos": 512, "end_pos": 555, "start_aa": "Val", "end_aa": "Lys", "glycosite_overlap": [] } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" }, { "name": "homologset.oma", "label": "OMA Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 202, "end_pos": 204 }, { "start_pos": 302, "end_pos": 304 }, { "start_pos": 482, "end_pos": 484 }, { "start_pos": 683, "end_pos": 685 }, { "start_pos": 92, "end_pos": 94 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ], "tool_support": { "graph_view": "yes" } }, { "uniprot_canonical_ac": "A0AAA9TUG4-1", "uniprot_ac": "A0AAA9TUG4", "uniprot_id": "A0AAA9TUG4_BOVIN", "mass": { "chemical_mass": 89028.0, "monoisotopic_mass": 89028.0 }, "refseq": { "ac": "XP_024851180", "name": "inactive N-acetylated-alpha-linked acidic dipeptidase-like protein 2 isoform X2", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_024851180" }, "gene_names": [ { "name": "NAALADL2", "type": "recommended", "evidence": [ { "id": "A0AAA9TUG4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TUG4" } ] }, { "name": "NAALADL2", "type": "synonym", "evidence": [ { "id": "XP_024851180", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_024851180" } ] } ], "protein_names": [ { "name": "N-acetylated alpha-linked acidic dipeptidase like 2", "type": "synonym", "evidence": [ { "id": "A0AAA9TUG4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TUG4/entry#names_and_taxonomy" } ] }, { "name": "inactive N-acetylated-alpha-linked acidic dipeptidase-like protein 2 isoform X2", "type": "synonym", "evidence": [ { "id": "XP_024851180", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_024851180" } ] } ], "function": [], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Bos taurus", "taxid": 9913, "evidence": [ { "database": "UniProtKB", "id": "A0AAA9TUG4", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TUG4" } ], "common_name": "Bovine", "glygen_name": "Bovine", "reference_species": "Bos taurus [9913]" } ], "gene": [ { "name": "NAALADL2", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TUG4", "locus": { "chromosome": "1", "start_pos": 91435008, "end_pos": 92802345, "strand": "+", "evidence": [ { "database": "Ensembl Gene", "id": "ENSBTAG00000048493", "url": "https://www.ensembl.org/id/ENSBTAG00000048493" } ] } } ], "crossref": [ { "id": "A0AAA9TUG4", "url": "https://alphafold.ebi.ac.uk/entry/A0AAA9TUG4", "database": "AlphaFoldDB", "categories": [] }, { "id": "ENSBTAG00000048493", "url": "https://bgee.org/?page=gene&gene_id=ENSBTAG00000048493", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "cd03874", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd03874", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "100337356", "url": "https://www.ncbi.nlm.nih.gov/gene/100337356", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR007484", "url": "https://www.ebi.ac.uk/interpro/entry/IPR007484", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR036757", "url": "https://www.ebi.ac.uk/interpro/entry/IPR036757", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR039373", "url": "https://www.ebi.ac.uk/interpro/entry/IPR039373", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR046450", "url": "https://www.ebi.ac.uk/interpro/entry/IPR046450", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "bta:100337356", "url": "https://www.genome.jp/dbget-bin/www_bget?bta:100337356", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "GYYAHKK", "url": "https://omabrowser.org/oma/group/GYYAHKK/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "PTHR10404", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR10404", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR10404:SF32", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR10404:SF32", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF04389", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF04389", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "XP_024851180", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_024851180", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A3Q1LJR9", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1LJR9", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A3Q1LJR9-1", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1LJR9-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A3Q1MHD1", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1MHD1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A3Q1MHD1-1", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1MHD1-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A3Q1N6C1", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1N6C1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A3Q1N6C1-1", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1N6C1-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0AAA9S836", "url": "https://www.uniprot.org/uniprotkb/A0AAA9S836", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0AAA9S836-1", "url": "https://www.uniprot.org/uniprotkb/A0AAA9S836-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0AAA9SV21", "url": "https://www.uniprot.org/uniprotkb/A0AAA9SV21", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0AAA9SV21-1", "url": "https://www.uniprot.org/uniprotkb/A0AAA9SV21-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0AAA9TPQ2", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TPQ2", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0AAA9TPQ2-1", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TPQ2-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0AAA9TS11", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TS11", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0AAA9TS11-1", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TS11-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0AAA9TUG4", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TUG4", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0AAA9TUG4-1", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TUG4-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MGENEASLPNTALQGKKMAYQKVNADQRAPGHSQYLDNDDLQATALDLEWDMEKELEEPGFDQFQLNSAENQNLENSETADLNLDPIQPATSPKGRFQRLQEESDYVTHYTRSAPKSNPRNFCRLLKIFCTAIILFISGILIGYYSHKNCPSNATSSGTLDLHLYQEILKTIQGEDIKKSFRNLVQLYKSEDDMDISKKIKTQWTSLGLEDVQLVNYSVLLNLPGLSPSSVTLSSSGQCFHPNGQPCSEEARKWSSQDLLYSYAAYSANGILEAEVIDVSYGNADDLKRIKKMKNVTNQIALLKLGKLPLLYKLSLLEKTGFGGVLLYIDPCDLPKTANLSYNTFMVSLNPGGDPSTPGYPSIDGSFRQHRSNLTSLLVQPISASLVAKLISLPKDRTTNGACSPLELPNNEERIVNMKIQTVTKFETVTNVVGYLKGVTFPDRYVIVGSHHHTAHSYNRQEWASSTAVITAFIRALMLRVKRGWRPDRTIVFCSWGGTAFGNIGSYEWGEDFRKVLQRNVVAYISLHSPVRGNSSLHSVASPSLQQLVAEKNKFNCPRRDQCPKTNISSEQIQDDADYFINHLGVPTVRFTYEDIKTLEGPSFLSEALFPKHATKIEEMDPFFNLHETITKLSGEVILQIANEPVLPFNALDIALEVQNSLKGDQTTTPQLLALASRLRESAELFQSDEMRPANDPKERDPMRVRMLNDLLQDMEKSFLVQHAPPGFYRNILYHLDGKTSQFSILLEAWEHCKSLASNETLQEALSEVLNSINAAQVYFKAGLDVFESVLVGKN", "length": 795, "header": "tr|A0AAA9TUG4-1|A0AAA9TUG4_BOVIN Isoform 1 of N-acetylated alpha-linked acidic dipeptidase like 2 OS=Bos taurus OX=9913 GN=NAALADL2 PE=3 SV=1 CANONICAL=A0AAA9TUG4-1" }, "isoforms": [ { "isoform_ac": "A0A3Q1LJR9-1", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1LJR9/entry", "sequence": { "sequence": "MGENEASLPNTALQGKKMAYQKVNADQRAPGHSQYLDNDDLQATALDLEWDMEKELEEPGFDQFQLNSAENQNLENSETADLNLDPIQPATSPKGRFQRLQEESDYVTHYTRSAPKSNPRNFCRLLKIFCTAIILFISGILIGYYSHKNCPSNATSSGTLDLHLYQEILKTIQGEDIKKSFRNLVQLYKSEDDMDISKKIKTQWTSLGLEDVQLVNYSVLLNLPGLSPSSVTLSSSGQCFHPNGQPCSEEARKWSSQDLLYSYAAYSANGILELSLLEKTGFGGVLLYIDPCDLPKTANLSYNTFMVSLNPGGDPSTPGYPSIDGSFRQHRSNLTSLLVQPISASLVAKLISLPKDRTTNGACSPLELPNNEERIVNMKIQTVTKFETVTNVVGYLKGVTFPDRYVIVGSHHHTAHSYNRQEWASSTAVITAFIRALMLRVKRGWRPDRTIVFCSWGGTAFGNIGSYEWGEDFRKVLQRNVVAYISLHSPVRGNSSLHSVASPSLQQLVAEKNKFNCPRRDQCPKTNISSEQIQDDADYFINHLGVPTVRFTYEDIKTLEGPSFLSEALFPKHATKIEEMDPFFNLHETITKLSGEVILQIANEPVLPFNALDIALEVQNSLKGDQTTTPQLLALASRLRESAELFQSDEMRPANDPKERDPMRVRMLNDLLQDMEKSFLVQHAPPGFYRNILYHLDGKTSQFSILLEAWEHCKSLASNETLQEALSEVLNSINAAQVYFKAGLDVFESVLVGKN", "length": 755, "header": "tr|A0A3Q1LJR9-1|A0AAA9TUG4_BOVIN Computationally mapped isoform of N-acetylated alpha-linked acidic dipeptidase like 2 OS=Bos taurus OX=9913 GN=NAALADL2 PE=3 SV=1 CANONICAL=A0AAA9TUG4-1" }, "locus": { "chromosome": "1", "start_pos": 92559222, "end_pos": 91436012, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000074778.2", "url": "https://www.ensembl.org/id/ENSBTAT00000074778.2" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000056708.2", "url": "https://www.ensembl.org/id/ENSBTAP00000056708.2" } ] } }, { "isoform_ac": "A0A3Q1MHD1-1", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1MHD1/entry", "sequence": { "sequence": "MAYQKVNADQRAPGHSQYLDNDDLQATALDLEWDMEKELEEPGFDQFQLNSAENQNLENSETADLNLDPIQPATSPKGRFQRLQEESDYVTHYTRSAPKSNPRNFCRLLKIFCTAIILFISGILIGYYSHKNCPSNATSSGTLDLHLYQEILKTIQGEDIKKSFRNLVQLYKSEDDMDISKKIKTQWTSLGLEDVQLVNYSVLLNLPGLSPSSVTLSSSGQCFHPNGQPCSEEARKWSSQDLLYSYAAYSANGILEAEVIDVSYGNADDLKRIKKMKNVTNQIALLKLGKLPLLYKLSLLEKTGFGGVLLYIDPCDLPKTANLSYNTFMVSLNPGGDPSTPGYPSIDGSFRQHRSNLTSLLVQPISASLVAKLISLPKDRTTNGACSPLELPNNEERIVNMKIQTVTKFETVTNVVGYLKGVTFPDRYVIVGSHHHTAHSYNRQEWASSTAVITAFIRALMLRVKRGWRPDRTIVFCSWGGTAFGNIGSYEWGEDFRKVLQRNVVAYISLHSPVRGNSSLHSVASPSLQQLVAEKNKFNCPRRDQCPKTNISSEQIQDDADYFINHLGVPTVRFTYEDIKTLEGPSFLSEALFPKHATKIEEMDPFFNLHETITKLSGEVILQIANEPVLPFNALDIALEVQNSLKGDQTTTPQLLALASRLRESAELFQSDEMRPANDPKERDPMRVRMLNDLLQDMEKSFLVQHAPPGFYRNILYHLDGKTSQFSILLEAWEHCKSLASNETLQEALSEVLNSINAAQVYFKAGLDVFESVLVGKN", "length": 778, "header": "tr|A0A3Q1MHD1-1|A0AAA9TUG4_BOVIN Computationally mapped isoform of N-acetylated alpha-linked acidic dipeptidase like 2 OS=Bos taurus OX=9913 GN=NAALADL2 PE=3 SV=1 CANONICAL=A0AAA9TUG4-1" }, "locus": { "chromosome": "1", "start_pos": 92278484, "end_pos": 91436012, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000078274.2", "url": "https://www.ensembl.org/id/ENSBTAT00000078274.2" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000073648.1", "url": "https://www.ensembl.org/id/ENSBTAP00000073648.1" } ] } }, { "isoform_ac": "A0A3Q1N6C1-1", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1N6C1/entry", "sequence": { "sequence": "MEHSKRTSAALTTACSALLYFHLCGNLLRFILLCKKMAYQKVNADQRAPGHSQYLDNDDLQATALDLEWDMEKELEEPGFDQFQLNSAENQNLENSETADLNLDPIQPATSPKGRFQRLQEESDYVTHYTRSAPKSNPRNFCRLLKIFCTAIILFISGILIGYYSHKNCPSNATSSGTLDLHLYQEILKTIQGEDIKKSFRNLVQLYKSEDDMDISKKIKTQWTSLGLEDVQLVNYSVLLNLPGLSPSSVTLSSSGQCFHPNGQPCSEEARKWSSQDLLYSYAAYSANGILEAEVIDVSYGNADDLKRIKKMKNVTNQIALLKLGKLPLLYKLSLLEKTGFGGVLLYIDPCDLPKTANLSYNTFMVSLNPGGDPSTPGYPSIDGSFRQHRSNLTSLLVQPISASLVAKLISLPKDRTTNGACSPLELPNNEERIVNMKIQTVTKFETVTNVVGYLKGVTFPDRYVIVGSHHHTAHSYNRQEWASSTAVITAFIRALMLRVKRGWRPDRTIVFCSWGGTAFGNIGSYEWGEDFRKVLQRNVVAYISLHSPVRGNSSLHSVASPSLQQLVAEKNKFNCPRRDQCPKTNISSEQIQDDADYFINHLGVPTVRFTYEDIKTLEGPSFLSEALFPKHATKIEEMDPFFNLHETITKLSGEVILQIANEPVLPFNALDIALEVQNSLKGDQTTTPQLLALASRLRESAELFQSDEMRPANDPKERDPMRVRMLNDLLQDMEKSFLVQHAPPGFYRRHKRQGFDP", "length": 758, "header": "tr|A0A3Q1N6C1-1|A0AAA9TUG4_BOVIN Computationally mapped isoform of N-acetylated alpha-linked acidic dipeptidase like 2 OS=Bos taurus OX=9913 GN=NAALADL2 PE=3 SV=2 CANONICAL=A0AAA9TUG4-1" }, "locus": { "chromosome": "1", "start_pos": 92396010, "end_pos": 91499185, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000079958.2", "url": "https://www.ensembl.org/id/ENSBTAT00000079958.2" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000065980.2", "url": "https://www.ensembl.org/id/ENSBTAP00000065980.2" } ] } }, { "isoform_ac": "A0AAA9S836-1", "url": "https://www.uniprot.org/uniprotkb/A0AAA9S836/entry", "sequence": { "sequence": "MEHSKRTSAALTTACSALLYFHLCGNLLRFILLCKKMAYQKVNADQRAPGHSQYLDNDDLQATALDLEWDMEKELEEPGFDQFQLNSAENQNLENSETADLNLDPIQPATSPKGRFQRLQEESDYVTHYTRSAPKSNPRNFCRLLKIFCTAIILFISGILIGYYSHKNCPSNATSSGTLDLHLYQEILKTIQGEDIKKSFRNLVQLYKSEDDMDISKKIKTQWTSLGLEDVQLVNYSVLLNLPGLSPSSVTLSSSGQCFHPNGQPCSEEARKWSSQDLLYSYAAYSANGILEAEVIDVSYGNADDLKRIKKMKNVTNQIALLKLGKLPLLYKLSLLEKTGFGGVLLYIDPCDLPKTANLSYNTFMVSLNPGGDPSTPGYPSIDGSFRQHRSNLTSLLVQPISASLVAKLISLPKDRTTNGACSPLELPNNEERIVNMKIQTVTKFETVTNVVGYLKGVTFPDRYVIVGSHHHTAHSYNRQEWASSTAVITAFIRALMLRVKRGWRPDRTIVFCSWGGTAFGNIGSYEWGEDFRKVLQRNVVAYISLHSPVRGNSSLHSVASPSLQQLVAEKNKFNCPRRDQCPKTNISSEQIQDDADYFINHLGVPTVRFTYEDIKTLEGPSFLSEALFPKHATKIEEMDPFFNLHETITKLSGEVILQIANEPVLPFNALDIALEVQNSLKGDQTTTPQLLALASRLRESAELFQSDEMRPANDPKERDPMRVRMLNDLLQDMEKSFLVQHAPPGFYRNILYHLDGKTSQFSILLEAWEHCKSLASNETLQEALSEVLNSINAAQVYFKAGLDVFESVLVGKN", "length": 814, "header": "tr|A0AAA9S836-1|A0AAA9TUG4_BOVIN Computationally mapped isoform of N-acetylated alpha-linked acidic dipeptidase like 2 OS=Bos taurus OX=9913 GN=NAALADL2 PE=3 SV=1 CANONICAL=A0AAA9TUG4-1" }, "locus": { "chromosome": "1", "start_pos": 92396010, "end_pos": 91436012, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000106639.1", "url": "https://www.ensembl.org/id/ENSBTAT00000106639.1" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000079493.1", "url": "https://www.ensembl.org/id/ENSBTAP00000079493.1" } ] } }, { "isoform_ac": "A0AAA9SV21-1", "url": "https://www.uniprot.org/uniprotkb/A0AAA9SV21/entry", "sequence": { "sequence": "MGENEASLPNTALQGKKMAYQKVNADQRAPGHSQYLDNDDLQATALDLEWDMEKELEEPGFDQFQLNSAENQNLENSETADLNLDPIQPATSPKGRFQRLQEESDYVTHYTRSAPKSNPRNFCRLLKIFCTAIILFISGILIGYYSHKNCPSNATSSGTLDLHLYQEILKTIQGEDIKKSFRNLVQLYKSEDDMDISKKIKTQWTSLGLEDVQLVNYSVLLNLPGLSPSSVTLSSSGQCFHPNGQPCSEEARKWSSQDLLYSYAAYSANGILEAEVIDVSYGNADDLKRIKKMKNVTNQIALLKLGKLPLLYKLSLLEKTGFGGVLLYIDPCDLPKTANLSYNTFMVSLNPGGDPSTPGYPSIDGSFRQHRSNLTSLLVQPISASLVAKLISLPKDRTTNGACSPLELPNNEERIVNMKIQTVTKFETVTNVVGYLKGVTFPDRYVIVGSHHHTAHSYNRQEWASSTAVITAFIRALMLRVKRGWRPDRTIVFCSWGGTAFGNIGSYEWGEDFRKVLQRNVVAYISLHSPVRGNSSLHSVASPSLQQLVAEKNKFNCPRRDQCPKTNISSEQIQDDADYFINHLGVPTVRFTYEDIKTLELSGEVILQIANEPVLPFNALDIALEVQNSLKGDQTTTPQLLALASRLRESAELFQSDEMRPANDPKERDPMRVRMLNDLLQDMEKSFLVQHAPPGFYRNILYHLDGKTSQFSILLEAWEHCKSLASNETLQEALSEVLNSINAAQVYFKAGLDVFESVLVGKN", "length": 763, "header": "tr|A0AAA9SV21-1|A0AAA9TUG4_BOVIN Computationally mapped isoform of N-acetylated alpha-linked acidic dipeptidase like 2 OS=Bos taurus OX=9913 GN=NAALADL2 PE=3 SV=1 CANONICAL=A0AAA9TUG4-1" }, "locus": { "chromosome": "1", "start_pos": 92559222, "end_pos": 91436012, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000120662.1", "url": "https://www.ensembl.org/id/ENSBTAT00000120662.1" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000087028.1", "url": "https://www.ensembl.org/id/ENSBTAP00000087028.1" } ] } }, { "isoform_ac": "A0AAA9TPQ2-1", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TPQ2/entry", "sequence": { "sequence": "MGENEASLPNTALQGDLSNPGMEPMWAALSGRFFTTELPGKKMAYQKVNADQRAPGHSQYLDNDDLQATALDLEWDMEKELEEPGFDQFQLNSAENQNLENSETADLNLDPIQPATSPKGRFQRLQEESDYVTHYTRSAPKSNPRNFCRLLKIFCTAIILFISGILIGYYSHKNCPSNATSSGTLDLHLYQEILKTIQGEDIKKSFRNLVQLYKSEDDMDISKKIKTQWTSLGLEDVQLVNYSVLLNLPGLSPSSVTLSSSGQCFHPNGQPCSEEARKWSSQDLLYSYAAYSANGILEAEVIDVSYGNADDLKRIKKMKNVTNQIALLKLGKLPLLYKLSLLEKTGFGGVLLYIDPCDLPKTANLSYNTFMVSLNPGGDPSTPGYPSIDGSFRQHRSNLTSLLVQPISASLVAKLISLPKDRTTNGACSPLELPNNEERIVNMKIQTVTKFETVTNVVGYLKGVTFPDRYVIVGSHHHTAHSYNRQEWASSTAVITAFIRALMLRVKRGWRPDRTIVFCSWGGTAFGNIGSYEWGEDFRKVLQRNVVAYISLHSPVRGNSSLHSVASPSLQQLVAEKNKFNCPRRDQCPKTNISSEQIQDDADYFINHLGVPTVRFTYEDIKTLEGPSFLSEALFPKHATKIEEMDPFFNLHETITKLSGEVILQIANEPVLPFNALDIALEVQNSLKGDQTTTPQLLALASRLRESAELFQSDEMRPANDPKERDPMRVRMLNDLLQDMEKSFLVQHAPPGFYRNILYHLDGKTSQFSILLEAWEHCKSLASNETLQEALSEVLNSINAAQVYFKAGLDVFESVLVGKN", "length": 820, "header": "tr|A0AAA9TPQ2-1|A0AAA9TUG4_BOVIN Computationally mapped isoform of N-acetylated alpha-linked acidic dipeptidase like 2 OS=Bos taurus OX=9913 GN=NAALADL2 PE=3 SV=1 CANONICAL=A0AAA9TUG4-1" }, "locus": { "chromosome": "1", "start_pos": 92559222, "end_pos": 91436012, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000130668.1", "url": "https://www.ensembl.org/id/ENSBTAT00000130668.1" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000100522.1", "url": "https://www.ensembl.org/id/ENSBTAP00000100522.1" } ] } }, { "isoform_ac": "A0AAA9TS11-1", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TS11/entry", "sequence": { "sequence": "MEHSKRTSAALTTACSALLYFHLCGNLLRFILLCKKMAYQKVNADQRAPGHSQYLDNDDLQATALDLEWDMEKELEEPGFDQFQLNSAENQNLENSETADLNLDPIQPATSPKGRFQRLQEESDYVTHYTRSAPKSNPRNFCRLLKIFCTAIILFISGILIGYYSHKNCPSNATSSGTLDLHLYQEILKTIQGEDIKKSFRNLVQLYKSEDDMDISKKIKTQWTSLGLEDVQLVNYSVLLNLPGLSPSSVTLSSSGQCFHPNGQPCSEEARKWSSQDLLYSYAAYSANGILEAEVIDVSYGNADDLKRIKKMKNVTNQIALLKLGKLPLLYKLSLLEKTGFGGVLLYIDPCDLPKTANLSYNTFMVSLNPGGDPSTPGYPSIDGSFRQHRSNLTSLLVQPISASLVAKLISLPKDRTTNGACSPLELPNNEERIVNMKIQTVTKFETVTNVVGYLKGVTFPDRYVIVGSHHHTAHSYNRQEWASSTAVITAFIRALMLRVKRGWRPDRTIVFCSWGGTAFGNIGSYEWGEDFRKVLQRNVVAYISLHSPVRGNSSLHSVASPSLQQLVAEKNKFNCPRRDQCPKTNISSEQIQDDADYFINHLGVPTVRFTYEDIKTLEGPSFLSEALFPKHATKIEEMDPFFNLHETITKLSGEVILQIANEPVLPFNALDIALEVQNSLKGDQTTTPQLLALASRLRESAELFQSDEMRPANDPKERDPMRVRMLNDLLQDMEKSFLVQHAPPGFYRGPKGERT", "length": 756, "header": "tr|A0AAA9TS11-1|A0AAA9TUG4_BOVIN Computationally mapped isoform of N-acetylated alpha-linked acidic dipeptidase like 2 OS=Bos taurus OX=9913 GN=NAALADL2 PE=3 SV=1 CANONICAL=A0AAA9TUG4-1" }, "locus": { "chromosome": "1", "start_pos": 92396010, "end_pos": 91489196, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000111361.1", "url": "https://www.ensembl.org/id/ENSBTAT00000111361.1" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000099827.1", "url": "https://www.ensembl.org/id/ENSBTAP00000099827.1" } ] } }, { "isoform_ac": "A0AAA9TUG4-1", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TUG4/entry", "sequence": { "sequence": "MGENEASLPNTALQGKKMAYQKVNADQRAPGHSQYLDNDDLQATALDLEWDMEKELEEPGFDQFQLNSAENQNLENSETADLNLDPIQPATSPKGRFQRLQEESDYVTHYTRSAPKSNPRNFCRLLKIFCTAIILFISGILIGYYSHKNCPSNATSSGTLDLHLYQEILKTIQGEDIKKSFRNLVQLYKSEDDMDISKKIKTQWTSLGLEDVQLVNYSVLLNLPGLSPSSVTLSSSGQCFHPNGQPCSEEARKWSSQDLLYSYAAYSANGILEAEVIDVSYGNADDLKRIKKMKNVTNQIALLKLGKLPLLYKLSLLEKTGFGGVLLYIDPCDLPKTANLSYNTFMVSLNPGGDPSTPGYPSIDGSFRQHRSNLTSLLVQPISASLVAKLISLPKDRTTNGACSPLELPNNEERIVNMKIQTVTKFETVTNVVGYLKGVTFPDRYVIVGSHHHTAHSYNRQEWASSTAVITAFIRALMLRVKRGWRPDRTIVFCSWGGTAFGNIGSYEWGEDFRKVLQRNVVAYISLHSPVRGNSSLHSVASPSLQQLVAEKNKFNCPRRDQCPKTNISSEQIQDDADYFINHLGVPTVRFTYEDIKTLEGPSFLSEALFPKHATKIEEMDPFFNLHETITKLSGEVILQIANEPVLPFNALDIALEVQNSLKGDQTTTPQLLALASRLRESAELFQSDEMRPANDPKERDPMRVRMLNDLLQDMEKSFLVQHAPPGFYRNILYHLDGKTSQFSILLEAWEHCKSLASNETLQEALSEVLNSINAAQVYFKAGLDVFESVLVGKN", "length": 795, "header": "tr|A0AAA9TUG4-1|A0AAA9TUG4_BOVIN Isoform 1 of N-acetylated alpha-linked acidic dipeptidase like 2 OS=Bos taurus OX=9913 GN=NAALADL2 PE=3 SV=1 CANONICAL=A0AAA9TUG4-1" }, "locus": { "chromosome": "1", "start_pos": 92559222, "end_pos": 91436012, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000129884.1", "url": "https://www.ensembl.org/id/ENSBTAT00000129884.1" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000100750.1", "url": "https://www.ensembl.org/id/ENSBTAP00000100750.1" } ] } } ], "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "other", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 357, "start_aa": "Thr", "end_pos": 357, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr357", "evidence": [ { "id": "", "database": "GlyGen", "url": "https://data.glygen.org/" } ], "filter_code": "000000000000000010000.00000000001000.0.01000" } ], "phosphorylation": [], "glycation": [], "keywords": [ "glycoprotein", "glycoprotein_predicted" ], "publication": [], "pathway": [ { "id": "bta:100337356", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?bta:100337356", "resource": "KEGG Pathway" } ], "orthologs": [ { "uniprot_canonical_ac": "A0A0N4SUJ3-1", "protein_name": "N-acetylated alpha-linked acidic dipeptidase-like 2", "gene_name": "Naaladl2", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MGENEAGLPNMSLQGKKMAYQKVKADLRTSGHSQYLDNDELQATALDLEWDMEKELEEPGFDQFQPDSAEHQNLGHSETLDLHLDSIQPATSPKGRFQRLQEESDCVTHYTRSAPKNNHCSFCYMLKILCIATTLFIFGIIIGYYAHMNCPSDASPSGTNNPQLYQDILKTIKAEDIKKSFRNWLQLYDSKDDMEIAKKIKSHWIALGLEDTQFINYSVLLDFPGSSPGTITLSSTGQCFYPDGQPCREEARGGHSQDLFFSYAAYSAKGTLQGDVIDVSYGTMDDLKRITKLKNTTNQIALLKLGKLPLLYKISLLEKAGFGGALLYIDPCDAAESSVLSSEPFVVTLNPGGDPSTPGYPSHDGSFRKSRTNLTSLLVQPISPSLVKMLISLPKLKMDKDACSPLELPHNEKRTVSLQVQTVTQFKTVSNVVGYLRGLTSPDRYIIVGSNHHAGYSYKGQEWASSTAVITAFIEAMMLRVKKGWRPERTIVFCSWGGTPWGKIGSYEWGEDFVKILQKNAVAYIGLHSPIRGNSSLYPVVSPSLQQLVIEKIKFTCMQRAQCLGANVSSVQIQGDADYFINHLGVPTVQFAYEDIKTLEGPSFLSEAIFPTHATKIEEVDPSFSLHEAITKLSGEVILQIANEPILPFNALDIALGVQNSLKGNEPSVPHLLALASRLRESAELFQSDEMRPANDPKERAPSRVRMLNDILQDLEKNFLVQWVPPGFYRNILYHLDEKTNQFSILKEAWEHCNPQTSNETFQEALSNVLNSINSAHISFKVGLDVFESVLLGKN", "length": 795 }, "evidence": [ { "id": "A0AAA9TUG4", "url": "https://omabrowser.org/oma/group/A0AAA9TUG4/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "A0A480QLP9-1", "protein_name": "N-acetylated alpha-linked acidic dipeptidase like 2", "gene_name": "NAALADL2", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MGENEASLPNTALQGKKMAYQKVNADQRAPGHSQYLDNDDLQATALDLEWDMEKELEEPGFDQFQLDSAENQNLEHAETADLNLDSIQPATSPKGRFQRLQEESDYITHYARSAPKSNPCNFCRLLKIFCTAIILFIFGILIGYYAHKNCPSNATSSGTLDLQLYQEILKTIQAEDIKKSFRNLIQLYKSEDDMEISKKIKIQWTSLGLEDVQFVNYSVLLNLPGPAPSSVTLSSSGQCFHPDGQPCSEEARKHSSQDLLYSYAAYSAKGTLKAEVIDVSYGNADDLKRIKKMKNVTNRIALLKLGRLPLLYKLSLLEKAGFGGVLLYIDPCDLPKTTNLSYDTFMVSLNPGGDPSTPGYPSIDGSFRQNRSNLTSLLVQPVSASLIAKLISSPKATTTNNACTPLELPNNEERIVNMQIQTVTKFKTVTNVVGYLKGLTSPDRYILVGSRHHTAYSYNGQEWASSTAIITAFIRALMLRVKRGWRPDRTIVFCSWGGTAFGNIGSYEWGEDFKKVLQRNVVAYVSLHSPIRGNSSLYSVASPSLQQLVAEKNNFNCSRRGQCPETNVSSVQMQDDADYFINHLGIPTVRFSYEDSQLSEGPSFLFEALFPKHTTKIEELDPFFNLHETITKLSGEVILQIANEPVLPFNALDIALEVQNSLKGDQPNTPQLLAPASRLRESTELFQSDEMRPANDPKERAPIRVRMLNDILQDMEKSFLVQHAPPGFYRNILYHLDGKTSQFSILLEAWEHCKSLASNETLQEALSEVLNSINAAQVYFKAGLDVFESILVGKN", "length": 795 }, "evidence": [ { "id": "A0AAA9TUG4", "url": "https://omabrowser.org/oma/group/A0AAA9TUG4/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "A0A8I6ACN8-1", "protein_name": "N-acetylated alpha-linked acidic dipeptidase-like 2", "gene_name": "Naaladl2", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MGENEAGLPNMALQGKKMAYHKVKADLRTSGHSQYLDSDDLQATALDLEWDMEKELEEPSFDQFQTDNAEHQNLGHSETLDLHLDSIQPATSPKGRFQRLQEESDCVTHYTRSAPKNNHCNFCYLLKILCIATTLFIFGIIIGYYAHMNCPSDASPSGTNNPQLYQDILKTIKAEDIKKSFRNLLQVYDSEDDMEISKKIKSHWIALGLEDTQFINYSVLLDCPGPSPGTITVSSTGQCFYPDGQPCREEARRGQSQDLFYSYAAYSAKGTLQADVIDVSYGTMDDLKRITKLKNTTNQIALLKLGKLPLLYKISLLEKAGFGGALLYIDPCDAPESAVLSSEPFMVTLNPGGDPSTPGYPSHDESFRQSRPNLTSLLVQPISASLATVLISSPKLRMDKDVCRPLELPHNEKRTVSLQVQTVTKFKTVSNVVGYLRGLTSPDRYIIVGSNHHAGHSYNGQEWASSTAVITAFIEALMLRVKKGWRPERTVVFCSWGGTPWGKIGSYEWGEDFAKILQKNAVAYVSIHSPIRGNSTLYPVASPSLQQLVLEKNKFNCVRRAQCPGANVSSVQIQGDAEYFVNHLGVPTVQFAYEDIKALEGPSFLSEAIFPKHATKIEELDPSFNLHEVITKLSGEVILQIANDPVLPFNALDIALGVQNSLKDNEPSVPNLLALASKLRDSAELFQSDEMRPANDPKERVPSRVRMLNDILQDLEKNFLVQRVPPGFYRNILYHLDEKTSQFSILKEAWEQCIPETSNETLQEALSTVLNSINSAHTFFKTGLDVFESVLLEKN", "length": 795 }, "evidence": [ { "id": "A0AAA9TUG4", "url": "https://omabrowser.org/oma/group/A0AAA9TUG4/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "A0A8V0ZDI2-1", "protein_name": "N-acetylated alpha-linked acidic dipeptidase like 2", "gene_name": "NAALADL2", "tax_id": 9031, "organism": "Gallus gallus", "sequence": { "sequence": "MCPFLALPYGESVKKMAYHKVNADQRTQGQYLDSDDLQATALELEWDMEKELEEPGFDHFRLDGAVQQDLGNSQSPDLDLEPIQPSASPKGRFQRLQEDPEYISHYTRQSPKSHRCSFFQILKVFCAALILFIFGIVIGYYAGKKCPSPPASPEPNNPHIYHEILKEIKAENIQQIYRDVLQSPREDDVDAAMRILLQWTSHGLEDVRLVNYSVLLDLPGSSSNTITLKNSGECFYPDGQQCSKVTRTLHSQDLLYSYAAYSAKGTLEAELVDIQYGTIEDLIRIQTTTNVTKKIALLKLGQSPLLYKLSLLEDAGFGGVLLYVDPCDLPKTTDLAEKAFMVSLNSGGDPSTPGYASIDGSYRQNRLNLTTLLVQPISAVLAKKLTSIPENRIQKDKCVPLQLSSTDKKIINLSIQSVTTYKTISNVIGYLKGSVFPDRYVIIGSHHSSLNTYGGQEWASSTAIITAFIQALMLKVKRGWRTDRTIVFCSWGGTSFGNIGSYEWAEDLKRVLQRNVVAYVSLHNPVRGNSTLHPIASPSLQQLAAESQNINCVEKMKCPGSNVSSVQTQGDSDYFINHLGVPAMQFSYEDINTSENSSFVSEALFPMHATRTEELDPSFKLHENIAKFSGYATLQIANEPVLPFNALDIALEVQNSLRVFLGEEVDASQLLAVASRLRDTAELFQSDEMRPANDPRERAPIRVRMLNDVLQSLEKSFLVQQAPPGLYRNILYRLDERTSQFSVLLEALEHCKLHQSNETIQATLSEVLNSISSAQVYFKAGLDVFETTLAGKK", "length": 793 }, "evidence": [ { "id": "A0AAA9TUG4", "url": "https://omabrowser.org/oma/group/A0AAA9TUG4/", "database": "OMA" } ], "glygen_name": "Chicken", "common_name": "Chicken" }, { "uniprot_canonical_ac": "Q58DX5-1", "protein_name": "Inactive N-acetylated-alpha-linked acidic dipeptidase-like protein 2", "gene_name": "NAALADL2", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MGENEASLPNTSLQGKKMAYQKVHADQRAPGHSQYLDNDDLQATALDLEWDMEKELEESGFDQFQLDGAENQNLGHSETIDLNLDSIQPATSPKGRFQRLQEESDYITHYTRSAPKSNRCNFCHVLKILCTATILFIFGILIGYYVHTNCPSDAPSSGTVDPQLYQEILKTIQAEDIKKSFRNLVQLYKNEDDMEISKKIKTQWTSLGLEDVQFVNYSVLLDLPGPSPSTVTLSSSGQCFHPNGQPCSEEARKDSSQDLLYSYAAYSAKGTLKAEVIDVSYGMADDLKRIRKIKNVTNQIALLKLGKLPLLYKLSSLEKAGFGGVLLYIDPCDLPKTVNPSHDTFMVSLNPGGDPSTPGYPSVDESFRQSRSNLTSLLVQPISAPLVAKLISSPKARTKNEACSSLELPNNEIRVVSMQVQTVTKLKTVTNVVGFVMGLTSPDRYIIVGSHHHTAHSYNGQEWASSTAIITAFIRALMSKVKRGWRPDRTIVFCSWGGTAFGNIGSYEWGEDFKKVLQKNVVAYISLHSPIRGNSSLYPVASPSLQQLVVEKNNFNCTRRAQCPETNISSIQIQGDADYFINHLGVPIVQFAYEDIKTLEGPSFLSEARFSTRATKIEEMDPSFNLHETITKLSGEVILQIANEPVLPFNALDIALEVQNNLKGDQPNTHQLLAMALRLRESAELFQSDEMRPANDPKERAPIRIRMLNDILQDMEKSFLVKQAPPGFYRNILYHLDEKTSRFSILIEAWEHCKPLASNETLQEALSEVLNSINSAQVYFKAGLDVFKSVLDGKN", "length": 795 }, "evidence": [ { "id": "A0AAA9TUG4", "url": "https://omabrowser.org/oma/group/A0AAA9TUG4/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" } ], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 2, "go_terms": [ { "name": "membrane", "id": "GO:0016020", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016020", "evidence": [ { "database": "UniProtKB", "id": "A0AAA9TUG4", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TUG4" } ], "pmid": "" }, { "name": "nucleoplasm", "id": "GO:0005654", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005654", "evidence": [ { "database": "UniProtKB", "id": "A0AAA9TUG4", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TUG4" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 153, "end_pos": 155, "annotation": "n_glycosylation_sequon" }, { "start_pos": 216, "end_pos": 218, "annotation": "n_glycosylation_sequon" }, { "start_pos": 295, "end_pos": 297, "annotation": "n_glycosylation_sequon" }, { "start_pos": 339, "end_pos": 341, "annotation": "n_glycosylation_sequon" }, { "start_pos": 373, "end_pos": 375, "annotation": "n_glycosylation_sequon" }, { "start_pos": 534, "end_pos": 536, "annotation": "n_glycosylation_sequon" }, { "start_pos": 567, "end_pos": 569, "annotation": "n_glycosylation_sequon" }, { "start_pos": 759, "end_pos": 761, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A0AAA9TUG4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TUG4" }, { "id": "PF04389", "database": "Pfam", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF04389" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "Peptidase M28", "eco_id": "ECO_0000259", "start_pos": 431, "end_pos": 593, "start_aa": "Asn", "end_aa": "Tyr", "glycosite_overlap": [] } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" }, { "name": "homologset.oma", "label": "OMA Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [ 357 ], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 153, "end_pos": 155 }, { "start_pos": 216, "end_pos": 218 }, { "start_pos": 295, "end_pos": 297 }, { "start_pos": 339, "end_pos": 341 }, { "start_pos": 373, "end_pos": 375 }, { "start_pos": 534, "end_pos": 536 }, { "start_pos": 567, "end_pos": 569 }, { "start_pos": 759, "end_pos": 761 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 1 }, { "field": "total_sites", "count": 1 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 1 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "exact_sites", "count": 1 }, { "field": "exact_o_linked_sites", "count": 1 }, { "field": "fuzzy_sites", "count": 0 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_pos", "start_aa", "end_pos", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 1 }, { "field": "total_sites", "count": 1 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 1 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "exact_sites", "count": 1 }, { "field": "exact_o_linked_sites", "count": 1 }, { "field": "fuzzy_sites", "count": 0 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_pos", "start_aa", "end_pos", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ], "tool_support": { "graph_view": "yes" } }, { "uniprot_canonical_ac": "A0AAA9TW87-1", "uniprot_ac": "A0AAA9TW87", "uniprot_id": "A0AAA9TW87_BOVIN", "mass": { "chemical_mass": 87546.0, "monoisotopic_mass": 87546.0 }, "refseq": {}, "gene_names": [ { "name": "PRDM4", "type": "recommended", "evidence": [ { "id": "A0AAA9TW87", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TW87" } ] } ], "protein_names": [ { "name": "PR domain zinc finger protein 4", "type": "recommended", "evidence": [ { "id": "A0AAA9TW87", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TW87/entry#names_and_taxonomy" } ] }, { "name": "PR domain-containing protein 4", "type": "synonym", "evidence": [ { "id": "A0AAA9TW87", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TW87/entry#names_and_taxonomy" } ] } ], "function": [ { "annotation": "May function as a transcription factor involved in cell differentiation.", "evidence": [ { "database": "UniProtKB", "id": "A0A3Q1LLD2", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1LLD2#function" }, { "database": "UniProtKB", "id": "PIRNR037161", "url": "https://www.uniprot.org/uniprotkb/PIRNR037161#function" }, { "database": "UniProtKB", "id": "ARBA00059546", "url": "https://www.uniprot.org/uniprotkb/ARBA00059546#function" }, { "database": "UniProtKB", "id": "E1BDK1", "url": "https://www.uniprot.org/uniprotkb/E1BDK1#function" }, { "database": "UniProtKB", "id": "A0AAA9TW87", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TW87#function" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Bos taurus", "taxid": 9913, "evidence": [ { "database": "UniProtKB", "id": "A0AAA9TW87", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TW87" } ], "common_name": "Bovine", "glygen_name": "Bovine", "reference_species": "Bos taurus [9913]" } ], "gene": [ { "name": "PRDM4", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TW87", "locus": { "chromosome": "5", "start_pos": 70974477, "end_pos": 71009717, "strand": "+", "evidence": [ { "database": "Ensembl Gene", "id": "ENSBTAG00000012999", "url": "https://www.ensembl.org/id/ENSBTAG00000012999" } ] } } ], "crossref": [ { "id": "A0AAA9TW87", "url": "https://alphafold.ebi.ac.uk/entry/A0AAA9TW87", "database": "AlphaFoldDB", "categories": [] }, { "id": "ENSBTAG00000012999", "url": "https://bgee.org/?page=gene&gene_id=ENSBTAG00000012999", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "cd19189", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd19189", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "540731", "url": "https://www.ncbi.nlm.nih.gov/gene/540731", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR001214", "url": "https://www.ebi.ac.uk/interpro/entry/IPR001214", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR013087", "url": "https://www.ebi.ac.uk/interpro/entry/IPR013087", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR017124", "url": "https://www.ebi.ac.uk/interpro/entry/IPR017124", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR036236", "url": "https://www.ebi.ac.uk/interpro/entry/IPR036236", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR041493", "url": "https://www.ebi.ac.uk/interpro/entry/IPR041493", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR044404", "url": "https://www.ebi.ac.uk/interpro/entry/IPR044404", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR046341", "url": "https://www.ebi.ac.uk/interpro/entry/IPR046341", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR050331", "url": "https://www.ebi.ac.uk/interpro/entry/IPR050331", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "bta:540731", "url": "https://www.genome.jp/dbget-bin/www_bget?bta:540731", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "E1BDK1", "url": "https://www.orthodb.org/?gene=E1BDK1", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR16515", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR16515", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR16515:SF2", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR16515:SF2", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00096", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00096", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF18445", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF18445", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF21549", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF21549", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "A0A3Q1LLD2", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1LLD2", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A3Q1LLD2-1", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1LLD2-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0AAA9TW87", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TW87", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0AAA9TW87-1", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TW87-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "E1BDK1", "url": "https://www.uniprot.org/uniprotkb/E1BDK1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "E1BDK1-1", "url": "https://www.uniprot.org/uniprotkb/E1BDK1-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MMNEMNLSPVGMEQLTSSSVSNALPVSGSHLGLAASPTHNAIPAPGLPVAIPNLGPSLSSLPSALSLMLPMGIGDRGVMCGLPERNYTLPPPPYPHLESSYFRTILPGILSYLADRPPPQYIHPNSINVDGNTALSIANNPSALDPYQSNGNVGLEPGIVSIDSRSVNTHGAQSLHPTDGHEVALDTTITMENVSRVTSPISTDGMAEELTMDGVAGEHTQIPNGSRSHEPLSVDSVSSNLAAETVGHGGVIPMHGNGLELPVVMETDHIASRVNGMSDSALSDSIHTVAMSTNSVSVALSTSHNLASLESVSLHEVGLSLEPVAVSSITQEVAMGTGHVDVSSDSLSFVPPSLQMEDSNSNKENMATLFTIWCTLCDRAYPSDCPDHGPVTFVPDTPIESRARLSLPKQLVLRQSIVGADVGVWTGETIPVRTCFGPLIGQQSHSMEVAEWTDKAVNHIWKIYHNGVLEFCIITTDENECNWMMFVRKARNREEQNLVAYPHDGKIYFCTSQDIPPENELLFYYSRDYAQQIGVPEHPDVHLCNCGKECSSYTEFKAHLSSHIHNHLPSHGHSSSHGPSHSKERKWKCSMCPQAFISPSKLHVHFMGHMGMKPHKCDFCSKAFSDPSNLRTHLKIHTGQKNYRCTLCDKSFTQKAHLESHMVIHTGEKNLKCDYCDKLFMRRQDLKQHVLIHTQERQIKCPKCDKLFLRTNHLKKHLNSHEGKRDYVCEKCTKAYLTKYHLTRHLKTCKGPTSSSSAQEEEEEDDSEEEELVDSVGTEDCRIGSAVYSADDSLSAHK", "length": 798, "header": "tr|A0AAA9TW87-1|A0AAA9TW87_BOVIN Isoform 1 of PR domain zinc finger protein 4 OS=Bos taurus OX=9913 GN=PRDM4 PE=4 SV=1 CANONICAL=A0AAA9TW87-1" }, "isoforms": [ { "isoform_ac": "A0A3Q1LLD2-1", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1LLD2/entry", "sequence": { "sequence": "MSARMNEMNLSPVGMEQLTSSSVSNALPVSGSHLGLAASPTHNAIPAPGLPVAIPNLGPSLSSLPSALSLMLPMGIGDRGVMCGLPERNYTLPPPPYPHLESSYFRTILPGILSYLADRPPPQYIHPNSINVDGNTALSIANNPSALDPYQSNGNVGLEPGIVSIDSRSVNTHGAQSLHPTDGHEVALDTTITMENVSRVTSPISTDGMAEELTMDGVAGEHTQIPNGSRSHEPLSVDSVSSNLAAETVGHGGVIPMHGNGLELPVVMETDHIASRVNGMSDSALSDSIHTVAMSTNSVSVALSTSHNLASLESVSLHEVGLSLEPVAVSSITQEVAMGTGHVDVSSDSLSFVPPSLQMEDSNSNKENMATLFTIWCTLCDRAYPSDCPDHGPVTFVPDTPIESRARLSLPKQLVLRQSIVGADVGVWTGETIPVRTCFGPLIGQQSHSMEVAEWTDKAVNHIWKIYHNGVLEFCIITTDENECNWMMFVRKARNREEQNLVAYPHDGKIYFCTSQDIPPENELLFYYSRDYAQQIGVPEHPDVHLCNCGKECSSYTEFKAHLSSHIHNHLPSHGHSSSHGPSHSKERKWKCSMCPQAFISPSKLHVHFMGHMGMKPHKCDFCSKAFSDPSNLRTHLKIHTGQKNYRCTLCDKSFTQKAHLESHMVIHTGEKNLKCDYCDKLFMRRQDLKQHVLIHTQERQIKCPKCDKLFLRTNHLKKHLNSHEGKRDYVCEKCTKAYLTKYHLTRHLKTCKGPTSSSSAQEEEEEDDSEEEELVDSVGTEDCRIGSAVYSADDSLSAHK", "length": 801, "header": "tr|A0A3Q1LLD2-1|A0AAA9TW87_BOVIN Computationally mapped isoform of PR domain zinc finger protein 4 OS=Bos taurus OX=9913 GN=PRDM4 PE=4 SV=1 CANONICAL=A0AAA9TW87-1" }, "locus": { "chromosome": "5", "start_pos": 71009580, "end_pos": 70975481, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000068507.2", "url": "https://www.ensembl.org/id/ENSBTAT00000068507.2" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000057348.2", "url": "https://www.ensembl.org/id/ENSBTAP00000057348.2" } ] } }, { "isoform_ac": "A0AAA9TW87-1", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TW87/entry", "sequence": { "sequence": "MMNEMNLSPVGMEQLTSSSVSNALPVSGSHLGLAASPTHNAIPAPGLPVAIPNLGPSLSSLPSALSLMLPMGIGDRGVMCGLPERNYTLPPPPYPHLESSYFRTILPGILSYLADRPPPQYIHPNSINVDGNTALSIANNPSALDPYQSNGNVGLEPGIVSIDSRSVNTHGAQSLHPTDGHEVALDTTITMENVSRVTSPISTDGMAEELTMDGVAGEHTQIPNGSRSHEPLSVDSVSSNLAAETVGHGGVIPMHGNGLELPVVMETDHIASRVNGMSDSALSDSIHTVAMSTNSVSVALSTSHNLASLESVSLHEVGLSLEPVAVSSITQEVAMGTGHVDVSSDSLSFVPPSLQMEDSNSNKENMATLFTIWCTLCDRAYPSDCPDHGPVTFVPDTPIESRARLSLPKQLVLRQSIVGADVGVWTGETIPVRTCFGPLIGQQSHSMEVAEWTDKAVNHIWKIYHNGVLEFCIITTDENECNWMMFVRKARNREEQNLVAYPHDGKIYFCTSQDIPPENELLFYYSRDYAQQIGVPEHPDVHLCNCGKECSSYTEFKAHLSSHIHNHLPSHGHSSSHGPSHSKERKWKCSMCPQAFISPSKLHVHFMGHMGMKPHKCDFCSKAFSDPSNLRTHLKIHTGQKNYRCTLCDKSFTQKAHLESHMVIHTGEKNLKCDYCDKLFMRRQDLKQHVLIHTQERQIKCPKCDKLFLRTNHLKKHLNSHEGKRDYVCEKCTKAYLTKYHLTRHLKTCKGPTSSSSAQEEEEEDDSEEEELVDSVGTEDCRIGSAVYSADDSLSAHK", "length": 798, "header": "tr|A0AAA9TW87-1|A0AAA9TW87_BOVIN Isoform 1 of PR domain zinc finger protein 4 OS=Bos taurus OX=9913 GN=PRDM4 PE=4 SV=1 CANONICAL=A0AAA9TW87-1" }, "locus": { "chromosome": "5", "start_pos": 70997697, "end_pos": 70975481, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000107851.1", "url": "https://www.ensembl.org/id/ENSBTAT00000107851.1" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000100880.1", "url": "https://www.ensembl.org/id/ENSBTAP00000100880.1" } ] } }, { "isoform_ac": "E1BDK1-1", "url": "https://www.uniprot.org/uniprotkb/E1BDK1/entry", "sequence": { "sequence": "MHHRMNEMNLSPVGMEQLTSSSVSNALPVSGSHLGLAASPTHNAIPAPGLPVAIPNLGPSLSSLPSALSLMLPMGIGDRGVMCGLPERNYTLPPPPYPHLESSYFRTILPGILSYLADRPPPQYIHPNSINVDGNTALSIANNPSALDPYQSNGNVGLEPGIVSIDSRSVNTHGAQSLHPTDGHEVALDTTITMENVSRVTSPISTDGMAEELTMDGVAGEHTQIPNGSRSHEPLSVDSVSSNLAAETVGHGGVIPMHGNGLELPVVMETDHIASRVNGMSDSALSDSIHTVAMSTNSVSVALSTSHNLASLESVSLHEVGLSLEPVAVSSITQEVAMGTGHVDVSSDSLSFVPPSLQMEDSNSNKENMATLFTIWCTLCDRAYPSDCPDHGPVTFVPDTPIESRARLSLPKQLVLRQSIVGADVVGVLPLIGVWTGETIPVRTCFGPLIGQQSHSMEVAEWTDKAVNHIWKIYHNGVLEFCIITTDENECNWMMFVRKARNREEQNLVAYPHDGKIYFCTSQDIPPENELLFYYSRDYAQQIGVPEHPDVHLCNCGKECSSYTEFKAHLSSHIHNHLPSHGHSSSHGPSHSKERKWKCSMCPQAFISPSKLHVHFMGHMGMKPHKCDFCSKAFSDPSNLRTHLKIHTGQKNYRCTLCDKSFTQKAHLESHMVIHTGEKNLKCDYCDKLFMRRQDLKQHVLIHTQERQIKCPKCDKLFLRTNHLKKHLNSHEGKRDYVCEKCTKAYLTKYHLTRHLKTCKGPTSSSSAQEEEEEDDSEEEELVDSVGTEDCRIGSAVYSADDSLSAHK", "length": 808, "header": "tr|E1BDK1-1|E1BDK1_BOVIN Computationally mapped isoform of PR domain zinc finger protein 4 OS=Bos taurus OX=9913 GN=PRDM4 PE=4 SV=3 CANONICAL=A0AAA9TW87-1" }, "locus": { "chromosome": "5", "start_pos": 70997906, "end_pos": 70975481, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000017284.6", "url": "https://www.ensembl.org/id/ENSBTAT00000017284.6" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000017284.6", "url": "https://www.ensembl.org/id/ENSBTAP00000017284.6" } ] } } ], "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "other", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 753, "start_aa": "Thr", "end_pos": 753, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr753", "evidence": [ { "id": "", "database": "GlyGen", "url": "https://data.glygen.org/" } ], "filter_code": "000000000000000010000.00000000001000.0.01000" } ], "phosphorylation": [], "glycation": [], "keywords": [ "glycoprotein", "glycoprotein_predicted" ], "publication": [], "pathway": [ { "id": "bta:540731", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?bta:540731", "resource": "KEGG Pathway" } ], "orthologs": [], "go_annotation": { "categories": [ { "name": "Molecular Function", "total": 6, "go_terms": [ { "name": "DNA binding", "id": "GO:0003677", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003677", "evidence": [ { "database": "UniProtKB", "id": "A0AAA9TW87", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TW87" } ], "pmid": "" }, { "name": "zinc ion binding", "id": "GO:0008270", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008270", "evidence": [ { "database": "UniProtKB", "id": "A0AAA9TW87", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TW87" } ], "pmid": "" }, { "name": "methyltransferase activity", "id": "GO:0008168", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008168", "evidence": [ { "database": "UniProtKB", "id": "A0AAA9TW87", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TW87" } ], "pmid": "" }, { "name": "histone methyltransferase binding", "id": "GO:1990226", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:1990226", "evidence": [ { "database": "UniProtKB", "id": "A0AAA9TW87", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TW87" } ], "pmid": "" }, { "name": "DNA-binding transcription factor activity, RNA polymerase II-specific", "id": "GO:0000981", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000981", "evidence": [ { "database": "UniProtKB", "id": "A0AAA9TW87", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TW87" } ], "pmid": "" }, { "name": "sequence-specific double-stranded DNA binding", "id": "GO:1990837", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:1990837", "evidence": [ { "database": "UniProtKB", "id": "A0AAA9TW87", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TW87" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 2, "go_terms": [ { "name": "nucleus", "id": "GO:0005634", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005634", "evidence": [ { "database": "UniProtKB", "id": "A0AAA9TW87", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TW87" } ], "pmid": "" }, { "name": "nucleoplasm", "id": "GO:0005654", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005654", "evidence": [ { "database": "UniProtKB", "id": "A0AAA9TW87", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TW87" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 3, "go_terms": [ { "name": "transcription by RNA polymerase II", "id": "GO:0006366", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006366", "evidence": [ { "database": "UniProtKB", "id": "A0AAA9TW87", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TW87" } ], "pmid": "" }, { "name": "methylation", "id": "GO:0032259", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0032259", "evidence": [ { "database": "UniProtKB", "id": "A0AAA9TW87", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TW87" } ], "pmid": "" }, { "name": "regulation of gene expression", "id": "GO:0010468", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0010468", "evidence": [ { "database": "UniProtKB", "id": "A0AAA9TW87", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TW87" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 193, "end_pos": 195, "annotation": "n_glycosylation_sequon" }, { "start_pos": 224, "end_pos": 226, "annotation": "n_glycosylation_sequon" }, { "start_pos": 6, "end_pos": 8, "annotation": "n_glycosylation_sequon" }, { "start_pos": 86, "end_pos": 88, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A0AAA9TW87", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TW87" }, { "id": "PS50157", "database": "PROSITE", "url": "https://prosite.expasy.org/PS50157" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "C2H2-type", "eco_id": "ECO_0000259", "start_pos": 587, "end_pos": 614, "start_aa": "Trp", "end_aa": "Pro", "glycosite_overlap": [] }, { "evidence": [ { "id": "A0AAA9TW87", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TW87" }, { "id": "PS50280", "database": "PROSITE", "url": "https://prosite.expasy.org/PS50280" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "SET", "eco_id": "ECO_0000259", "start_pos": 409, "end_pos": 526, "start_aa": "Lys", "end_aa": "Ser", "glycosite_overlap": [] } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [ 753 ], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 193, "end_pos": 195 }, { "start_pos": 224, "end_pos": 226 }, { "start_pos": 6, "end_pos": 8 }, { "start_pos": 86, "end_pos": 88 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 1 }, { "field": "total_sites", "count": 1 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 1 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "exact_sites", "count": 1 }, { "field": "exact_o_linked_sites", "count": 1 }, { "field": "fuzzy_sites", "count": 0 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_pos", "start_aa", "end_pos", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 1 }, { "field": "total_sites", "count": 1 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 1 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "exact_sites", "count": 1 }, { "field": "exact_o_linked_sites", "count": 1 }, { "field": "fuzzy_sites", "count": 0 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_pos", "start_aa", "end_pos", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ], "tool_support": { "graph_view": "yes" } }, { "uniprot_canonical_ac": "A0AAA9TVT5-1", "uniprot_ac": "A0AAA9TVT5", "uniprot_id": "A0AAA9TVT5_BOVIN", "mass": { "chemical_mass": 108488.0, "monoisotopic_mass": 108488.0 }, "refseq": {}, "gene_names": [ { "name": "CASK", "type": "recommended", "evidence": [ { "id": "A0AAA9TVT5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TVT5" } ] } ], "protein_names": [ { "name": "Peripheral plasma membrane protein CASK", "type": "recommended", "evidence": [ { "id": "A0AAA9TVT5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TVT5/entry#names_and_taxonomy" } ] }, { "name": "2.7.11.1", "type": "synonym", "evidence": [ { "id": "A0AAA9TVT5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TVT5/entry#names_and_taxonomy" } ] }, { "name": "Calcium/calmodulin-dependent serine protein kinase", "type": "synonym", "evidence": [ { "id": "A0AAA9TVT5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TVT5/entry#names_and_taxonomy" } ] } ], "function": [], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Bos taurus", "taxid": 9913, "evidence": [ { "database": "UniProtKB", "id": "A0AAA9TVT5", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TVT5" } ], "common_name": "Bovine", "glygen_name": "Bovine", "reference_species": "Bos taurus [9913]" } ], "gene": [ { "name": "CASK", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TVT5", "locus": { "chromosome": "X", "start_pos": 102072977, "end_pos": 101700082, "strand": "-", "evidence": [ { "database": "Ensembl Gene", "id": "ENSBTAG00000020136", "url": "https://www.ensembl.org/id/ENSBTAG00000020136" } ] } } ], "crossref": [ { "id": "A0AAA9TVT5", "url": "https://alphafold.ebi.ac.uk/entry/A0AAA9TVT5", "database": "AlphaFoldDB", "categories": [] }, { "id": "ENSBTAG00000020136", "url": "https://bgee.org/?page=gene&gene_id=ENSBTAG00000020136", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "cd00071", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd00071", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "cd10831", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd10831", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "cd12081", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd12081", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "cd14094", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd14094", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "404149", "url": "https://www.ncbi.nlm.nih.gov/gene/404149", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR000719", "url": "https://www.ebi.ac.uk/interpro/entry/IPR000719", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR001452", "url": "https://www.ebi.ac.uk/interpro/entry/IPR001452", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR001478", "url": "https://www.ebi.ac.uk/interpro/entry/IPR001478", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR004172", "url": "https://www.ebi.ac.uk/interpro/entry/IPR004172", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR008144", "url": "https://www.ebi.ac.uk/interpro/entry/IPR008144", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR008145", "url": "https://www.ebi.ac.uk/interpro/entry/IPR008145", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR011009", "url": "https://www.ebi.ac.uk/interpro/entry/IPR011009", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR014775", "url": "https://www.ebi.ac.uk/interpro/entry/IPR014775", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR020590", "url": "https://www.ebi.ac.uk/interpro/entry/IPR020590", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR027417", "url": "https://www.ebi.ac.uk/interpro/entry/IPR027417", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR035473", "url": "https://www.ebi.ac.uk/interpro/entry/IPR035473", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR036028", "url": "https://www.ebi.ac.uk/interpro/entry/IPR036028", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR036034", "url": "https://www.ebi.ac.uk/interpro/entry/IPR036034", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR036892", "url": "https://www.ebi.ac.uk/interpro/entry/IPR036892", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR050716", "url": "https://www.ebi.ac.uk/interpro/entry/IPR050716", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "A0A3Q1LMD0", "url": "https://www.orthodb.org/?gene=A0A3Q1LMD0", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A3Q1LPV4", "url": "https://www.orthodb.org/?gene=A0A3Q1LPV4", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A3Q1N8J3", "url": "https://www.orthodb.org/?gene=A0A3Q1N8J3", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR23122", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR23122", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00069", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00069", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF00595", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00595", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF00625", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00625", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF02828", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF02828", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF07653", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF07653", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "R-BTA-212676", "url": "https://www.reactome.org/PathwayBrowser/#R-BTA-212676", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "R-BTA-6794361", "url": "https://www.reactome.org/PathwayBrowser/#R-BTA-6794361", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "17989", "url": "https://www.rhea-db.org/rhea/17989", "database": "Rhea", "categories": [ "Enzyme and Pathway" ] }, { "id": "46608", "url": "https://www.rhea-db.org/rhea/46608", "database": "Rhea", "categories": [ "Enzyme and Pathway" ] }, { "id": "A0A3Q1LMD0", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1LMD0", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A3Q1LMD0-1", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1LMD0-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A3Q1LPV4", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1LPV4", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A3Q1LPV4-1", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1LPV4-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A3Q1N8J3", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1N8J3", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A3Q1N8J3-1", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1N8J3-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0AAA9TVT5", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TVT5", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0AAA9TVT5-1", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TVT5-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "G5E5P2", "url": "https://www.uniprot.org/uniprotkb/G5E5P2", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "G5E5P2-1", "url": "https://www.uniprot.org/uniprotkb/G5E5P2-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MADDDVLFEDVYELCEVIGKGPFSVVRRCINRETGQQFAVKIVDVAKFTSSPGLSTEDLKREASICHMLKHPHIVELLETYSSDGMLYMVFEFMDGADLCFEIVKRADAGFVYSEAVASHYMRQILEALRYCHDNNIIHRDVKPHCVLLASKENSAPVKLGGFGVAIQLGESGLVAGGRVGTPHFMAPEVVKREPYGKPVDVWGCGVILFILLSGCLPFYGTKERLFEGIIKGKYKMNPRQWSHISESAKDLVRRMLMLDPAERITVYEALNHPWLKERDRYAYKIHLPETVEQLRKFNARRKLKGAVLAAVSSHKFNSFYGDPPEELPDFSEDPTSSGAVSQVLDSLEEIHALTDCSEKDLDFLHSVFQDQHLHTLLDLYDKINTKSSPQIRNPPSDAVQRAKEVLEEISCYPENNDAKELKRILTQPHFMALLQTHDVVAHEVYSDEALRVTPPPTSPYLNGDSPESANGDMDMENVTRVRLVQFQKNTDEPMGITLKMNELNHCIVARIMHGGMIHRQGTLHVGDEIREINGISVANQTVEQLQKMLREMRGSITFKIVPSYRTQSSSCERDSPSTSRQSPANGHSSTNNSVSDLPSTTQPKGRQIYVRAQFEYDPAKDDLIPCKEAGIRFRVGDIIQIISKDDHNWWQGKLENSKNGTAGLIPSPELQEWRVACIAMEKTKQEQQASCTWFGKKKKQYKDKYLAKHNADLVTYEEVVKLPAFKRKTLVLLGAHGVGRRHIKNTLITKHPDRFAYPIPHTTRPPKKDEENGKNYYFVSHDQMMQDISNNEYLEYGSHEDAMYGTKLETIRKIHEQGLIAILDVEPQGLEKSSGQGWLEAKSQSWSWSSTPCPWVPHWSSPERRFLLALKVLRTAEFAPFVVFIAAPTITPGLNEDESLQRLQKESDILQRTYAHYFDLTIINNEIDETIRHLEEAVEHVCTAPQWVPVSWVY", "length": 955, "header": "tr|A0AAA9TVT5-1|A0AAA9TVT5_BOVIN Isoform 1 of Peripheral plasma membrane protein CASK OS=Bos taurus OX=9913 GN=CASK PE=3 SV=1 CANONICAL=A0AAA9TVT5-1" }, "isoforms": [ { "isoform_ac": "A0A3Q1LMD0-1", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1LMD0/entry", "sequence": { "sequence": "MADDDVLFEDVYELCEVIGKGPFSVVRRCINRETGQQFAVKIVDVAKFTSSPGLSTEGKRWISNLKREASICHMLKHPHIVELLETYSSDGMLYMVFEFMDGADLCFEIVKRADAGFVYSEAVASHYMRQILEALRYCHDNNIIHRDVKPHCVLLASKENSAPVKLGGFGVAIQLGESGLVAGGRVGTPHFMAPEVVKREPYGKPVDVWGCGVILFILLSGCLPFYGTKERLFEGIIKGKYKMNPRQWSHISESAKDLVRRMLMLDPAERITVYEALNHPWLKERDRYAYKIHLPETVEQLRKFNARRKLKGAVLAAVSSHKFNSFYGDPPEELPDFSEDPTSSGLLAAERAVSQVLDSLEEIHALTDCSEKDLDFLHSVFQDQHLHTLLDLYDKINTKSSPQIRNPPSDAVQRAKEVLEEISCYPENNDAKELKRILTQPHFMALLQTHDVVAHEVYSDEALRVTPPPTSPYLNGDSPESANGDMDMENVTRVRLVQFQKNTDEPMGITLKMNELNHCIVARIMHGGMIHRQGTLHVGDEIREINGISVANQTVEQLQKMLREMRGSITFKIVPSYRTQSSSCEDLPSTTQPKGRQIYVRAQFEYDPAKDDLIPCKEAGIRFRVGDIIQIISKDDHNWWQGKLENSKNGTAGLIPSPELQEWRVACIAMEKTKQEQQASCTWFGKKKKQYKDKYLAKHNADLVTYEEVVKLPAFKRKTLVLLGAHGVGRRHIKNTLITKHPDRFAYPIPHTTRPPKKDEENGKNYYFVSHDQMMQDISNNEYLEYGSHEDAMYGTKLETIRKIHEQGLIAILDVEPQALKVLRTAEFAPFVVFIAAPTITPGLNEDESLQRLQKESDILQRTYAHYFDLTIINNEIDETIRHLEEAVEHVCTAPQWVPVSWVY", "length": 904, "header": "tr|A0A3Q1LMD0-1|A0AAA9TVT5_BOVIN Computationally mapped isoform of Peripheral plasma membrane protein CASK OS=Bos taurus OX=9913 GN=CASK PE=3 SV=2 CANONICAL=A0AAA9TVT5-1" }, "locus": { "chromosome": "X", "start_pos": 102072585, "end_pos": 101700238, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000067007.2", "url": "https://www.ensembl.org/id/ENSBTAT00000067007.2" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000057798.2", "url": "https://www.ensembl.org/id/ENSBTAP00000057798.2" } ] } }, { "isoform_ac": "A0A3Q1LPV4-1", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1LPV4/entry", "sequence": { "sequence": "MADDDVLFEDVYELCEVIGKGPFSVVRRCINRETGQQFAVKIVDVAKFTSSPGLSTEGKRWISNLKREASICHMLKHPHIVELLETYSSDGMLYMVFEFMDGADLCFEIVKRADAGFVYSEAVASHYMRQILEALRYCHDNNIIHRDVKPHCVLLASKENSAPVKLGGFGVAIQLGESGLVAGGRVGTPHFMAPEVVKREPYGKPVDVWGCGVILFILLSGCLPFYGTKERLFEGIIKGKYKMNPRQWSHISESAKDLVRRMLMLDPAERITVYEALNHPWLKERDRYAYKIHLPETVEQLRKFNARRKLKGAVLAAVSSHKFNSFYGDPPEELPDFSEDPTSSGLLAAERAVSQVLDSLEEIHALTDCSEKDLDFLHSVFQDQHLHTLLDLYDKINTKSSPQIRNPPSDAVQRAKEVLEEISCYPENNDAKELKRILTQPHFMALLQTHDVVAHEVYSDEALRVTPPPTSPYLNGDSPESANGDMDMENVTRVRLVQFQKNTDEPMGITLKMNELNHCIVARIMHGGMIHRQGTLHVGDEIREINGISVANQTVEQLQKMLREMRGSITFKIVPSYRTQSSSCERDSPSTSRQSPANGHSSTNNSVSDLPSTTQPKGRQIYVRAQFEYDPAKDDLIPCKEAGIRFRVGDIIQIISKDDHNWWQGKLENSKNGTAGLIPSPELQEWRVACIAMEKTKQEQQASCTWFGKKKKQYKDKYLAKHNADLVTYEEVVKLPAFKRKTLVLLGAHGVGRRHIKNTLITKHPDRFAYPIPHTTRPPKKDEENGKNYYFVSHDQMMQDISNNEYLEYGSHEDAMYGTKLETIRKIHEQGLIAILDVEPQALKVLRTAEFAPFVVFIAAPTITPGLNEDESLQRLQKESDILQRTYAHYFDLTIINNEIDETIRHLEEAVEHVCTAPQWVPVSWVY", "length": 927, "header": "tr|A0A3Q1LPV4-1|A0A3Q1LPV4_BOVIN Computationally mapped isoform of Peripheral plasma membrane protein CASK OS=Bos taurus OX=9913 GN=CASK PE=3 SV=2 CANONICAL=A0AAA9TVT5-1" }, "locus": { "chromosome": "X", "start_pos": 102072585, "end_pos": 101700238, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000071329.2", "url": "https://www.ensembl.org/id/ENSBTAT00000071329.2" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000062140.2", "url": "https://www.ensembl.org/id/ENSBTAP00000062140.2" } ] } }, { "isoform_ac": "A0A3Q1N8J3-1", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1N8J3/entry", "sequence": { "sequence": "MADDDVLFEDVYELCEVIGKGPFSVVRRCINRETGQQFAVKIVDVAKFTSSPGLSTEGKRWISNLKREASICHMLKHPHIVELLETYSSDGMLYMVFEFMDGADLCFEIVKRADAGFVYSEAVASHYMRQILEALRYCHDNNIIHRDVKPHCVLLASKENSAPVKLGGFGVAIQLGESGLVAGGRVGTPHFMAPEVVKREPYGKPVDVWGCGVILFILLSGCLPFYGTKERLFEGIIKGKYKMNPRQWSHISESAKDLVRRMLMLDPAERITVYEALNHPWLKERDRYAYKIHLPETVEQLRKFNARRKLKGAVLAAVSSHKFNSFYGDPPEELPDFSEDPTSSGAVSQVLDSLEEIHALTDCSEKDLDFLHSVFQDQHLHTLLDLYDKINTKSSPQIRNPPSDAVQRAKEVLEEISCYPENNDAKELKRILTQPHFMALLQTHDVVAHEVYSDEALRVTPPPTSPYLNGDSPESANGDMDMENVTRVRLVQFQKNTDEPMGITLKMNELNHCIVARIMHGGMIHRQGTLHVGDEIREINGISVANQTVEQLQKMLREMRGSITFKIVPSYRTQSSSCEIYVRAQFEYDPAKDDLIPCKEAGIRFRVGDIIQIISKDDHNWWQGKLENSKNGTAGLIPSPELQEWRVACIAMEKTKQEQQASCTWFGKKKKQYKDKYLAKHNAVFDQLDLVTYEEVVKLPAFKRKTLVLLGAHGVGRRHIKNTLITKHPDRFAYPIPHTTRPPKKDEENGKNYYFVSHDQMMQDISNNEYLEYGSHEDAMYGTKLETIRKIHEQGLIAILDVEPQALKVLRTAEFAPFVVFIAAPTITPGLNEDESLQRLQKESDILQRTYAHYFDLTIINNEIDETIRHLEEAVEHVCTAPQWVPVSWVY", "length": 891, "header": "tr|A0A3Q1N8J3-1|A0AAA9TVT5_BOVIN Computationally mapped isoform of Peripheral plasma membrane protein CASK OS=Bos taurus OX=9913 GN=CASK PE=3 SV=2 CANONICAL=A0AAA9TVT5-1" }, "locus": { "chromosome": "X", "start_pos": 102072585, "end_pos": 101700238, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000079216.2", "url": "https://www.ensembl.org/id/ENSBTAT00000079216.2" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000067365.2", "url": "https://www.ensembl.org/id/ENSBTAP00000067365.2" } ] } }, { "isoform_ac": "A0AAA9TVT5-1", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TVT5/entry", "sequence": { "sequence": "MADDDVLFEDVYELCEVIGKGPFSVVRRCINRETGQQFAVKIVDVAKFTSSPGLSTEDLKREASICHMLKHPHIVELLETYSSDGMLYMVFEFMDGADLCFEIVKRADAGFVYSEAVASHYMRQILEALRYCHDNNIIHRDVKPHCVLLASKENSAPVKLGGFGVAIQLGESGLVAGGRVGTPHFMAPEVVKREPYGKPVDVWGCGVILFILLSGCLPFYGTKERLFEGIIKGKYKMNPRQWSHISESAKDLVRRMLMLDPAERITVYEALNHPWLKERDRYAYKIHLPETVEQLRKFNARRKLKGAVLAAVSSHKFNSFYGDPPEELPDFSEDPTSSGAVSQVLDSLEEIHALTDCSEKDLDFLHSVFQDQHLHTLLDLYDKINTKSSPQIRNPPSDAVQRAKEVLEEISCYPENNDAKELKRILTQPHFMALLQTHDVVAHEVYSDEALRVTPPPTSPYLNGDSPESANGDMDMENVTRVRLVQFQKNTDEPMGITLKMNELNHCIVARIMHGGMIHRQGTLHVGDEIREINGISVANQTVEQLQKMLREMRGSITFKIVPSYRTQSSSCERDSPSTSRQSPANGHSSTNNSVSDLPSTTQPKGRQIYVRAQFEYDPAKDDLIPCKEAGIRFRVGDIIQIISKDDHNWWQGKLENSKNGTAGLIPSPELQEWRVACIAMEKTKQEQQASCTWFGKKKKQYKDKYLAKHNADLVTYEEVVKLPAFKRKTLVLLGAHGVGRRHIKNTLITKHPDRFAYPIPHTTRPPKKDEENGKNYYFVSHDQMMQDISNNEYLEYGSHEDAMYGTKLETIRKIHEQGLIAILDVEPQGLEKSSGQGWLEAKSQSWSWSSTPCPWVPHWSSPERRFLLALKVLRTAEFAPFVVFIAAPTITPGLNEDESLQRLQKESDILQRTYAHYFDLTIINNEIDETIRHLEEAVEHVCTAPQWVPVSWVY", "length": 955, "header": "tr|A0AAA9TVT5-1|A0AAA9TVT5_BOVIN Isoform 1 of Peripheral plasma membrane protein CASK OS=Bos taurus OX=9913 GN=CASK PE=3 SV=1 CANONICAL=A0AAA9TVT5-1" }, "locus": { "chromosome": "X", "start_pos": 102072585, "end_pos": 101700238, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000090757.1", "url": "https://www.ensembl.org/id/ENSBTAT00000090757.1" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000101528.1", "url": "https://www.ensembl.org/id/ENSBTAP00000101528.1" } ] } }, { "isoform_ac": "G5E5P2-1", "url": "https://www.uniprot.org/uniprotkb/G5E5P2/entry", "sequence": { "sequence": "MADDDVLFEDVYELCEVIGKGPFSVVRRCINRETGQQFAVKIVDVAKFTSSPGLSTEDLKREASICHMLKHPHIVELLETYSSDGMLYMVFEFMDGADLCFEIVKRADAGFVYSEAVASHYMRQILEALRYCHDNNIIHRDVKPHCVLLASKENSAPVKLGGFGVAIQLGESGLVAGGRVGTPHFMAPEVVKREPYGKPVDVWGCGVILFILLSGCLPFYGTKERLFEGIIKGKYKMNPRQWSHISESAKDLVRRMLMLDPAERITVYEALNHPWLKERDRYAYKIHLPETVEQLRKFNARRKLKGAVLAAVSSHKFNSFYGDPPEELPDFSEDPTSSGLLAAERAVSQVLDSLEEIHALTDCSEKDLDFLHSVFQDQHLHTLLDLYDKINTKSSPQIRNPPSDAVQRAKEVLEEISCYPENNDAKELKRILTQPHFMALLQTHDVVAHEVYSDEALRVTPPPTSPYLNGDSPESANGDMDMENVTRVRLVQFQKNTDEPMGITLKMNELNHCIVARIMHGGMIHRQGTLHVGDEIREINGISVANQTVEQLQKMLREMRGSITFKIVPSYRTQSSSCERDSPSTSRQSPANGHSSTNNSVSIYVRAQFEYDPAKDDLIPCKEAGIRFRVGDIIQIISKDDHNWWQGKLENSKNGTAGLIPSPELQEWRVACIAMEKTKQEQQASCTWFGKKKKQYKDKYLAKHNADLVTYEEVVKLPAFKRKTLVLLGAHGVGRRHIKNTLITKHPDRFAYPIPHTTRPPKKDEENGKNYYFVSHDQMMQDISNNEYLEYGSHEDAMYGTKLETIRKIHEQGLIAILDVEPQALKVLRTAEFAPFVVFIAAPTITPGLNEDESLQRLQKESDILQRTYAHYFDLTIINNEIDETIRHLEEAVEHVCTAPQWVPVSWVY", "length": 909, "header": "tr|G5E5P2-1|G5E5P2_BOVIN Computationally mapped isoform of Peripheral plasma membrane protein CASK OS=Bos taurus OX=9913 GN=CASK PE=3 SV=1 CANONICAL=A0AAA9TVT5-1" }, "locus": { "chromosome": "X", "start_pos": 102072585, "end_pos": 101700238, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000026825.7", "url": "https://www.ensembl.org/id/ENSBTAT00000026825.7" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000026825.6", "url": "https://www.ensembl.org/id/ENSBTAP00000026825.6" } ] } } ], "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "other", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 892, "start_aa": "Thr", "end_pos": 892, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr892", "evidence": [ { "id": "", "database": "GlyGen", "url": "https://data.glygen.org/" } ], "filter_code": "000000000000000010000.00000000001000.0.01000" } ], "phosphorylation": [], "glycation": [], "keywords": [ "enzyme", "glycoprotein", "glycoprotein_predicted" ], "publication": [], "pathway": [ { "id": "R-BTA-212676", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-BTA-212676", "resource": "Reactome", "description": "Dopamine Neurotransmitter Release Cycle" }, { "id": "R-BTA-6794361", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-BTA-6794361", "resource": "Reactome", "description": "Neurexins and neuroligins" } ], "orthologs": [], "go_annotation": { "categories": [ { "name": "Molecular Function", "total": 4, "go_terms": [ { "name": "protein serine/threonine kinase activity", "id": "GO:0004674", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0004674", "evidence": [ { "database": "UniProtKB", "id": "A0AAA9TVT5", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TVT5" } ], "pmid": "" }, { "name": "calmodulin binding", "id": "GO:0005516", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005516", "evidence": [ { "database": "UniProtKB", "id": "A0AAA9TVT5", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TVT5" } ], "pmid": "" }, { "name": "ATP binding", "id": "GO:0005524", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005524", "evidence": [ { "database": "UniProtKB", "id": "A0AAA9TVT5", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TVT5" } ], "pmid": "" }, { "name": "signaling receptor binding", "id": "GO:0005102", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005102", "evidence": [ { "database": "UniProtKB", "id": "A0AAA9TVT5", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TVT5" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 6, "go_terms": [ { "name": "plasma membrane", "id": "GO:0005886", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005886", "evidence": [ { "database": "UniProtKB", "id": "A0AAA9TVT5", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TVT5" } ], "pmid": "" }, { "name": "cell junction", "id": "GO:0030054", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030054", "evidence": [ { "database": "UniProtKB", "id": "A0AAA9TVT5", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TVT5" } ], "pmid": "" }, { "name": "nucleus", "id": "GO:0005634", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005634", "evidence": [ { "database": "UniProtKB", "id": "A0AAA9TVT5", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TVT5" } ], "pmid": "" }, { "name": "cytoplasm", "id": "GO:0005737", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005737", "evidence": [ { "database": "UniProtKB", "id": "A0AAA9TVT5", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TVT5" } ], "pmid": "" }, { "name": "cell-cell junction", "id": "GO:0005911", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005911", "evidence": [ { "database": "UniProtKB", "id": "A0AAA9TVT5", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TVT5" } ], "pmid": "" }, { "name": "basolateral plasma membrane", "id": "GO:0016323", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016323", "evidence": [ { "database": "UniProtKB", "id": "A0AAA9TVT5", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TVT5" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 2, "go_terms": [ { "name": "regulation of neurotransmitter secretion", "id": "GO:0046928", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0046928", "evidence": [ { "database": "UniProtKB", "id": "A0AAA9TVT5", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TVT5" } ], "pmid": "" }, { "name": "intracellular protein localization", "id": "GO:0008104", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008104", "evidence": [ { "database": "UniProtKB", "id": "A0AAA9TVT5", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TVT5" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 478, "end_pos": 480, "annotation": "n_glycosylation_sequon" }, { "start_pos": 540, "end_pos": 542, "annotation": "n_glycosylation_sequon" }, { "start_pos": 592, "end_pos": 594, "annotation": "n_glycosylation_sequon" }, { "start_pos": 660, "end_pos": 662, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [ { "id": "17989", "name": "", "equation": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+)", "summary": "", "cellular_location": "", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [ "G5E5K2-1", "V6F977-1", "A0A3Q1MRW3-1", "A0A3Q1N860-1", "E1BI01-1", "F6RG88-1", "A0AAA9T8T9-1", "A0AAA9U1R3-1", "A7E3X2-1", "A0AAA9U1M9-1", "E1B754-1", "A0AAA9T7L6-1", "A0A3Q1M9F0-1", "A0ABI0P3P6-1", "E1BNH0-1", "A0AAA9TMV7-1", "A0AAA9T2F0-1", "A0AAA9S663-1", "A0AAA9U1A4-1", "F1MKY9-1", "A0AAA9S472-1", "F1MN35-1", "A0AAA9SMH0-1", "A0AAA9RSQ6-1", "F1N2S7-1", "F1N3W6-1", "A0AAA9S5X7-1", "F6QVY2-1", "A0A3Q1NKC2-1", "F1N5U0-1", "A0A3Q1MUZ6-1", "A0AAA9SJ92-1", "A0A3Q1LYH3-1", "A0A3Q1MXI5-1", "A0AAA9TJD5-1", "E1BBM3-1", "F1MG29-1", "A0AAA9SGM8-1", "A0AAA9SXE3-1", "P05131-1", "E1BHE1-1", "A0A3Q1LGC2-1", "A0A3Q1NBC4-1", "F6QTX4-1", "A0AAA9SWA1-1", "A0AAA9TDL1-1", "F1MU35-1", "A5D791-1", "F1N664-1", "F1MAZ8-1", "F1MH23-1", "A0A3S5ZPR2-1", "F1MWN0-1", "P48734-1", "A0AAA9SNP6-1", "A0AAA9RVB1-1", "A0A3Q1MLK5-1", "A0AAF6Z257-1", "F6RPH3-1", "F1MC27-1", "A0A3Q1M614-1", "A0ABI0NQQ4-1", "F1N332-1", "A7MB74-1", "A0AAA9RW51-1", "Q3SZJ2-1", "F1MXH6-1", "Q5E9L6-1", "A1A4I4-1", "A0AAF6YHL8-1", "Q08DZ2-1", "A0A3Q1LR28-1", "Q3MHJ9-1", "P00517-1", "Q3SYZ2-1", "A2VDU3-1", "Q3SWY6-1", "A0AAA9T5C9-1", "A7E3S4-1", "F1MI60-1", "E1BK52-1", "Q5E9X2-1", "Q17R13-1", "P68399-1", "F6Q6K1-1", "A0ABI0P0X3-1", "A0AAA9TNL3-1", "A0AAA9S4Z4-1", "E1B8P9-1", "Q2HJF7-1", "A0AAA9S9A9-1", "E1BG90-1", "F1MGX2-1", "A0A3Q1M4X3-1", "E1BN63-1", "A0A3Q1LNU2-1", "F1MKK7-1", "A0AAA9SMT9-1", "A0A3Q1MKC7-1", "A0A3Q1LTC6-1", "A0AAA9TD48-1", "A0A3Q1MEZ6-1", "E1BPU0-1", "A0A3Q1N707-1", "A0A3Q1LNA9-1", "F1MBN7-1", "E1BJM5-1", "F1MFK1-1", "A0A3Q1LKG0-1", "Q1RMT7-1", "G5E5D4-1", "F1MYV9-1", "A0AAA9T584-1", "A0AAA9SLY1-1", "Q2TA06-1", "Q5E9Y0-1", "A0AAA9RWB8-1", "A0AAA9SX77-1", "A0A3Q1MRR6-1", "A2VDV2-1", "A2VDZ4-1", "A5PKJ4-1", "E1BB50-1", "E1BB52-1", "F1MH24-1", "E1BCU9-1", "E1BFR5-1", "F1MDC9-1", "F1MNP4-1", "F1MQ96-1", "A0AAA9SU81-1", "P00516-1", "A0A3Q1LJU7-1", "A0A3Q1MS69-1", "A0A3Q1LU59-1", "A0A3Q1N4A7-1", "F1MY82-1", "F6RP02-1", "A7MBB4-1", "E1BMN8-1", "Q32KY4-1", "Q32PI1-1", "Q4TVR5-1", "Q5EAB2-1", "Q6TJY3-1", "E1B7H4-1", "E1BJ19-1", "E1BP01-1", "A0AAA9T940-1", "F1MC61-1", "E1BC64-1", "E1BNS8-1", "F1MPF0-1", "G5E518-1", "Q7YRC6-1", "Q95KV0-1", "Q9N0P9-1", "P20427-1", "P35507-1", "P35509-1", "P32871-1", "P35508-1", "P67827-1", "P04409-1", "P05126-1", "P05128-1", "P46196-1", "H2XJE9-1", "Q0VD22-1", "Q2KJG8-1", "Q2TBL8-1", "Q32L23-1", "Q3SX21-1", "Q3SZW1-1", "Q01314-1", "Q02399-1", "Q08E52-1", "Q0V7M1-1", "Q1RMT8-1", "Q2KIP2-1", "Q2LGB3-1", "Q2TA25-1", "Q3T0N5-1", "A0A3Q1LM61-1", "A0A3Q1LRM6-1", "E1BPB5-1", "A0A3Q1MHH5-1", "A0A3Q1M4N6-1", "G3MX00-1", "F1MH45-1", "A0A3Q1M334-1", "A0A3Q1M9L7-1", "A0A3Q1MA37-1", "A0A3Q1MHL3-1", "E1BP72-1", "A0AAA9T7Z7-1", "Q58D94-1", "F1MJ55-1", "Q17QV9-1", "F1N6C1-1", "G3N2F6-1", "A0AAA9T3K7-1", "F1MPI8-1", "F1MVV5-1", "F6RD87-1", "G3N2D2-1", "G5E577-1", "E1B887-1", "E1B902-1", "E1BAL6-1", "E1BH31-1", "E1BJH5-1", "E1BK33-1", "F1MG77-1", "F1MKW8-1", "A0AAA9SJQ0-1", "E1BL08-1", "E1B793-1", "E1B9B6-1", "E1BFV2-1", "A0AAA9T042-1", "A0AAA9TU12-1", "A0AAA9T593-1", "Q2YDN8-1", "A0AAA9SK35-1", "A0AAA9RSJ2-1", "A0AAA9T7I8-1", "Q3T0P6-1", "A0A3Q1LWT7-1", "A0AAA9S954-1", "E1B9F9-1", "A0AAA9RWC6-1", "F6RLA2-1", "E1BCH5-1", "H2XJE8-1", "A0A3Q1LL42-1", "A0AAA9SVM5-1", "F1MYG2-1", "A0A3Q1LLH8-1", "A0A3Q1LN49-1", "A0A3Q1M5T5-1", "A0A3Q1LW88-1", "A0ABI0P2C0-1", "A0AAA9SG01-1", "F6PN06-1", "E1BC36-1", "E1BB49-1", "E1BDG4-1", "E1BKX9-1", "E1BM19-1", "E1BQ34-1", "A0ABI0P443-1", "A0A3Q1LQP3-1", "A0A3Q1MNB4-1", "A0AAA9TWW0-1", "E1BGV8-1", "A0AAA9SIK7-1", "A0AAA9T8Z3-1", "F1N063-1", "A0A3Q1MD82-1", "F1N5K1-1", "E1BN72-1", "F1MLY7-1", "A0AAA9TVT5-1", "A0AAA9SKK8-1", "A0AAA9RTJ4-1", "A0AAA9TNE6-1", "F1MWP1-1", "G3N022-1", "A0AAA9TCI9-1", "A0AAA9TLV0-1", "E1B8J7-1", "F1MIB2-1", "E1B827-1", "E1BEI6-1", "A0A3Q1M1Z0-1", "F1MYM3-1", "G3N2J4-1", "F1MSV4-1", "E1B9Q2-1", "A0ABI0NJ75-1", "A0A3Q1M2U5-1", "A0A3Q1MI36-1", "A0A3Q1LLF0-1", "A0A3Q1M6N5-1", "A0A3Q1NFM1-1", "A0AAF6DLR2-1", "A0ABI0NV47-1", "E1BPP1-1", "E1BC69-1", "E1BCC3-1", "E1BEW4-1", "F1MF36-1", "A0AAA9SH90-1", "E1BLQ5-1", "F1MG35-1", "F1MSI1-1", "F1MSX4-1", "F1MVR0-1", "F1MY55-1", "G5E5A0-1", "F1MUU2-1", "F1MY86-1", "A0AAA9SJA3-1", "F6Q5Z6-1", "A0AAA9TP92-1", "A0AAA9S2N3-1", "A0A3Q1MHM3-1", "F6QY93-1", "F6Q5B6-1", "A0AAA9SYW5-1", "A0A3Q1LH95-1", "A0AAF6DMH7-1", "A0AAF6YMX3-1", "F6Q9U9-1", "A0A3Q1MW77-1", "F1MF50-1", "P52175-1", "Q8MIT6-1", "Q28021-1", "Q5E9Y9-1", "A0ABI0NMT8-1", "A0ABI0NRQ5-1", "F1MM88-1", "A0ABI0NM98-1", "A0ABI0NS30-1", "A0ABI0P3N8-1" ], "evidence": [ { "id": "17989", "database": "Rhea", "url": "https://www.rhea-db.org/rhea/17989" } ] }, { "id": "46608", "name": "", "equation": "L-threonyl-[protein] + ATP = O-phospho-L-threonyl-[protein] + ADP + H(+)", "summary": "", "cellular_location": "", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [ "G5E5K2-1", "V6F977-1", "A0A3Q1MRW3-1", "A0A3Q1N860-1", "E1BI01-1", "F6RG88-1", "A0AAA9T8T9-1", "A0AAA9U1R3-1", "A7E3X2-1", "A0AAA9U1M9-1", "E1B754-1", "A0AAA9T7L6-1", "A0A3Q1M9F0-1", "A0ABI0P3P6-1", "E1BNH0-1", "A0AAA9TMV7-1", "A0AAA9T2F0-1", "A0AAA9S663-1", "A0AAA9U1A4-1", "F1MKY9-1", "A0AAA9S472-1", "F1MN35-1", "A0AAA9SMH0-1", "A0AAA9RSQ6-1", "F1N2S7-1", "F1N3W6-1", "A0AAA9S5X7-1", "F6QVY2-1", "A0A3Q1NKC2-1", "F1N5U0-1", "A0A3Q1MUZ6-1", "A0AAA9SJ92-1", "A0AAA9U136-1", "A0A3Q1LYH3-1", "A0A3Q1MXI5-1", "A0AAA9TJD5-1", "E1BBM3-1", "E1BEW4-1", "A0AAA9SK35-1", "F1MG29-1", "A0AAA9SGM8-1", "A0AAA9SXE3-1", "P05131-1", "E1BHE1-1", "A0A3Q1LGC2-1", "A0A3Q1NBC4-1", "F6QTX4-1", "A0AAA9SWA1-1", "A0AAA9TDL1-1", "F1MU35-1", "A5D791-1", "F1N664-1", "A0AAA9T3H7-1", "F1MAZ8-1", "F1MH23-1", "A0A3S5ZPR2-1", "F1MWN0-1", "P48734-1", "A0AAA9SNP6-1", "A0AAA9RVB1-1", "A0AAF6Z257-1", "A0A3Q1M614-1", "A0ABI0NQQ4-1", "E1BEI6-1", "F1N332-1", "A7MB74-1", "Q3SZJ2-1", "F1MXH6-1", "Q5E9L6-1", "A0AAF6YHL8-1", "Q08DZ2-1", "A0A3Q1LR28-1", "Q3MHJ9-1", "P00517-1", "Q3SYZ2-1", "A2VDU3-1", "P67827-1", "P05126-1", "F6RPH3-1", "A0AAA9T5C9-1", "Q3SWY6-1", "A7E3S4-1", "A1A4I4-1", "F1MI60-1", "E1BK52-1", "Q5E9X2-1", "Q17R13-1", "P68399-1", "F6Q6K1-1", "A0ABI0P0X3-1", "A0AAA9TNL3-1", "A0AAA9S4Z4-1", "F6PN06-1", "E1B8P9-1", "Q2HJF7-1", "A0AAA9S9A9-1", "E1BG90-1", "F1MGX2-1", "A0A3Q1M4X3-1", "E1BN63-1", "A0A3Q1LNU2-1", "F1MKK7-1", "A0AAA9SMT9-1", "A0A3Q1MKC7-1", "A0A3Q1LTC6-1", "A0AAA9TD48-1", "A0A3Q1MEZ6-1", "E1BPU0-1", "A0A3Q1N707-1", "A0A3Q1LNA9-1", "F1MBN7-1", "E1BJM5-1", "F1MFK1-1", "A0A3Q1LKG0-1", "Q1RMT7-1", "G5E5D4-1", "F1MYV9-1", "A0AAA9T584-1", "A0AAA9SLY1-1", "Q2TA06-1", "Q5E9Y0-1", "A0AAA9RWB8-1", "A0AAA9SX77-1", "A0A3Q1MRR6-1", "A0A3Q1N9F5-1", "A2VDV2-1", "A2VDZ4-1", "A5PKJ4-1", "E1BB50-1", "E1BB52-1", "F1MH24-1", "E1BCU9-1", "E1BFR5-1", "F1MDC9-1", "F1MNP4-1", "F1MQ96-1", "A0AAA9SU81-1", "P00516-1", "A0A3Q1LJU7-1", "A0A3Q1MS69-1", "A0A3Q1LU59-1", "A0A3Q1N4A7-1", "F1MY82-1", "F6RP02-1", "A7MBB4-1", "E1BMN8-1", "Q32KY4-1", "Q32PI1-1", "Q4TVR5-1", "Q5EAB2-1", "Q6TJY3-1", "E1B7H4-1", "E1BJ19-1", "E1BP01-1", "A0AAA9T940-1", "F1MC61-1", "E1BC64-1", "E1BNS8-1", "F1MPF0-1", "G5E518-1", "Q7YRC6-1", "Q95KV0-1", "Q9N0P9-1", "P20427-1", "P35507-1", "P35509-1", "P35508-1", "P46196-1", "P04409-1", "P05128-1", "H2XJE9-1", "Q0VD22-1", "Q2TBL8-1", "Q32L23-1", "Q3SX21-1", "Q3SZW1-1", "Q01314-1", "Q02399-1", "Q08E52-1", "Q0V7M1-1", "Q1RMT8-1", "Q2KIP2-1", "Q2LGB3-1", "Q2TA25-1", "Q3T0N5-1", "A0A3Q1LM61-1", "A0A3Q1LRM6-1", "E1BPB5-1", "A0A3Q1MHH5-1", "A0A3Q1M4N6-1", "G3MX00-1", "F1MH45-1", "A0A3Q1M334-1", "A0A3Q1M9L7-1", "A0A3Q1MA37-1", "A0A3Q1MHL3-1", "E1BP72-1", "A0AAA9T7Z7-1", "Q58D94-1", "F1MJ55-1", "E1BI47-1", "Q17QV9-1", "F1N6C1-1", "G3N2F6-1", "A0AAA9T3K7-1", "F1MPI8-1", "F1MVV5-1", "F6RD87-1", "G3N2D2-1", "G5E577-1", "E1B887-1", "E1B902-1", "E1BAL6-1", "E1BH31-1", "E1BJH5-1", "E1BK33-1", "F1MG77-1", "F1MKW8-1", "A0AAA9SJQ0-1", "E1BL08-1", "E1B793-1", "E1B7L9-1", "E1B9B6-1", "E1BFV2-1", "A0AAA9T042-1", "A0AAA9TU12-1", "A0AAA9T593-1", "A0A3Q1MI36-1", "A0AAA9RSJ2-1", "A0A3Q1NFM1-1", "A0AAA9T7I8-1", "A0A3Q1LWT7-1", "A0AAA9S954-1", "E1B9F9-1", "A0AAA9RWC6-1", "F6RLA2-1", "E1BCH5-1", "H2XJE8-1", "A0A3Q1LL42-1", "A0AAA9SVM5-1", "F1MYG2-1", "A0A3Q1LLH8-1", "A0A3Q1LN49-1", "A0A3Q1M5T5-1", "A0A3Q1LW88-1", "A0ABI0P2C0-1", "A0AAA9SG01-1", "E1BC36-1", "E1BB49-1", "E1BDG4-1", "E1BKX9-1", "E1BM19-1", "E1BQ34-1", "A0ABI0P443-1", "A0A3Q1LQP3-1", "A0A3Q1MNB4-1", "A0AAA9TWW0-1", "E1BGV8-1", "A0AAA9SIK7-1", "A0AAA9T8Z3-1", "F1N063-1", "A0A3Q1MD82-1", "F1N5K1-1", "E1BN72-1", "F1MLY7-1", "A0AAA9TVT5-1", "A0AAA9SKK8-1", "A0AAA9TNE6-1", "F1MWP1-1", "G3N022-1", "A0A3Q1MLK5-1", "A0AAA9TCI9-1", "F1MC27-1", "A0AAA9RW51-1", "A0AAA9TLV0-1", "E1B8J7-1", "F1MIB2-1", "E1B827-1", "A0A3Q1M1Z0-1", "G3N2J4-1", "F1MSV4-1", "E1B9Q2-1", "A0ABI0NJ75-1", "A0A3Q1M2U5-1", "A0A3Q1LLF0-1", "A0A3Q1M6N5-1", "A0AAF6DLR2-1", "A0ABI0NV47-1", "E1BPP1-1", "E1BC69-1", "E1BCC3-1", "F1MF36-1", "A0AAA9SH90-1", "E1BLQ5-1", "F1MG35-1", "F1MSI1-1", "F1MSX4-1", "F1MVR0-1", "F1MY55-1", "G5E5A0-1", "F1MUU2-1", "F1MY86-1", "A0AAA9SJA3-1", "F6Q5Z6-1", "A0AAA9TP92-1", "A0AAA9S2N3-1", "A0A3Q1MHM3-1", "F6QY93-1", "F6Q5B6-1", "A0AAA9SYW5-1", "A0A3Q1LH95-1", "A0AAF6DMH7-1", "A0AAF6YMX3-1", "F6Q9U9-1", "A0A3Q1MW77-1", "F1MF50-1", "P52175-1", "Q8MIT6-1", "Q28021-1", "A0ABI0NRQ5-1", "F1MDS3-1", "F1MM88-1", "A0ABI0NM98-1", "A0ABI0NS30-1", "A0ABI0P3N8-1" ], "evidence": [ { "id": "46608", "database": "Rhea", "url": "https://www.rhea-db.org/rhea/46608" } ] }, { "id": "R-BTA-380574", "name": "Dopamine synaptic vesicle docking and priming", "equation": "", "summary": "This event has been computationally inferred from an event that has been demonstrated in another species.

The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.

More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "cellular_location": "cytosol, plasma membrane, clathrin-sculpted monoamine transport vesicle membrane", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [ "P11023-1", "A0AAA9TVT5-1" ], "evidence": [ { "id": "R-BTA-380574", "database": "Reactome", "url": "https://www.reactome.org/PathwayBrowser/#R-BTA-380574" } ] }, { "id": "R-BTA-5336443", "name": "LIN7, CASK and APBA1 bind", "equation": "", "summary": "This event has been computationally inferred from an event that has been demonstrated in another species.

The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.

More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "cellular_location": "cytosol, plasma membrane", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [ "A0AAA9TVT5-1" ], "evidence": [ { "id": "R-BTA-5336443", "database": "Reactome", "url": "https://www.reactome.org/PathwayBrowser/#R-BTA-5336443" } ] }, { "id": "R-BTA-6797553", "name": "Protein 4.1 binds CASK", "equation": "", "summary": "This event has been computationally inferred from an event that has been demonstrated in another species.

The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.

More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "cellular_location": "cytosol", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [ "A0AAA9TVT5-1" ], "evidence": [ { "id": "R-BTA-6797553", "database": "Reactome", "url": "https://www.reactome.org/PathwayBrowser/#R-BTA-6797553" } ] }, { "id": "R-BTA-6797568", "name": "NRXNs bind CASK:Protein 4.1", "equation": "", "summary": "This event has been computationally inferred from an event that has been demonstrated in another species.

The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.

More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "cellular_location": "cytosol, plasma membrane", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [ "A0AAA9TVT5-1" ], "evidence": [ { "id": "R-BTA-6797568", "database": "Reactome", "url": "https://www.reactome.org/PathwayBrowser/#R-BTA-6797568" } ] } ], "reaction_participants": [], "reaction_enzymes": [ { "uniprot_ac": "A0A3Q1LGC2", "gene_name": "HUNK", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A3Q1LGC2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1LGC2" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A3Q1LGC2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1LGC2" } ] } ] }, { "uniprot_ac": "A0A3Q1LH95", "gene_name": "MAP3K20", "activity": [ { "ec_number": "2.7.11.25", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A3Q1LH95", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1LH95" } ] }, { "ec_number": "2.7.11.25", "activity": "", "evidence": [ { "id": "A0A3Q1LH95", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1LH95" } ] } ] }, { "uniprot_ac": "A0A3Q1LJU7", "gene_name": "MAPK9", "activity": [ { "ec_number": "2.7.11.24", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A3Q1LJU7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1LJU7" } ] }, { "ec_number": "2.7.11.24", "activity": "", "evidence": [ { "id": "A0A3Q1LJU7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1LJU7" } ] } ] }, { "uniprot_ac": "A0A3Q1LKG0", "gene_name": "MINK1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A3Q1LKG0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1LKG0" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A3Q1LKG0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1LKG0" } ] } ] }, { "uniprot_ac": "A0A3Q1LL42", "gene_name": "SBK2", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A3Q1LL42", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1LL42" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A3Q1LL42", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1LL42" } ] } ] }, { "uniprot_ac": "A0A3Q1LLF0", "gene_name": "PIK3R4", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A3Q1LLF0", "database": "UniProtKB", "url": 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"ec_number": "2.7.11.13", "activity": "", "evidence": [ { "id": "A0A3Q1LM61", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1LM61" } ] } ] }, { "uniprot_ac": "A0A3Q1LN49", "gene_name": "CDK17", "activity": [ { "ec_number": "2.7.11.22", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A3Q1LN49", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1LN49" } ] }, { "ec_number": "2.7.11.22", "activity": "", "evidence": [ { "id": "A0A3Q1LN49", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1LN49" } ] } ] }, { "uniprot_ac": "A0A3Q1LNA9", "gene_name": "PAK3", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A3Q1LNA9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1LNA9" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": 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"uniprot_ac": "A0A3Q1LQP3", "gene_name": "KSR1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A3Q1LQP3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1LQP3" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A3Q1LQP3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1LQP3" } ] } ] }, { "uniprot_ac": "A0A3Q1LR28", "gene_name": "TESK2", "activity": [ { "ec_number": "2.7.12.1", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A3Q1LR28", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1LR28" } ] }, { "ec_number": "2.7.12.1", "activity": "", "evidence": [ { "id": "A0A3Q1LR28", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1LR28" } ] } ] }, { "uniprot_ac": "A0A3Q1LRM6", "gene_name": "MAPK10", "activity": 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{ "id": "A0A3Q1M4X3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1M4X3" } ] } ] }, { "uniprot_ac": "A0A3Q1M5T5", "gene_name": "CAMK4", "activity": [ { "ec_number": "2.7.11.17", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A3Q1M5T5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1M5T5" } ] }, { "ec_number": "2.7.11.17", "activity": "", "evidence": [ { "id": "A0A3Q1M5T5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1M5T5" } ] } ] }, { "uniprot_ac": "A0A3Q1M614", "gene_name": "MAPKAPK2", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A3Q1M614", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1M614" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A3Q1M614", "database": "UniProtKB", "url": 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ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A3Q1MHH5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1MHH5" } ] }, { "ec_number": "2.7.11.25", "activity": "", "evidence": [ { "id": "A0A3Q1MHH5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1MHH5" } ] } ] }, { "uniprot_ac": "A0A3Q1MHL3", "gene_name": "LIMK2", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A3Q1MHL3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1MHL3" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A3Q1MHL3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1MHL3" } ] } ] }, { "uniprot_ac": "A0A3Q1MHM3", "gene_name": "HIPK2", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A3Q1MHM3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1MHM3" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A3Q1MHM3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1MHM3" } ] } ] }, { "uniprot_ac": "A0A3Q1MI36", "gene_name": "", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A3Q1MI36", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1MI36" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A3Q1MI36", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1MI36" } ] } ] }, { "uniprot_ac": "A0A3Q1MKC7", "gene_name": "CAMK2A", "activity": [ { "ec_number": "2.7.11.17", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A3Q1MKC7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1MKC7" } ] }, { "ec_number": "2.7.11.17", "activity": "", "evidence": [ { "id": "A0A3Q1MKC7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1MKC7" } ] } ] }, { "uniprot_ac": "A0A3Q1MLK5", "gene_name": "LMTK2", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A3Q1MLK5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1MLK5" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A3Q1MLK5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1MLK5" } ] } ] }, { "uniprot_ac": "A0A3Q1MNB4", "gene_name": "STK32A", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A3Q1MNB4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1MNB4" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A3Q1MNB4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1MNB4" } ] } ] }, { "uniprot_ac": "A0A3Q1MRR6", "gene_name": "PRKCD", "activity": [ { "ec_number": "2.7.11.13", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A3Q1MRR6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1MRR6" } ] }, { "ec_number": "2.7.11.13", "activity": "", "evidence": [ { "id": "A0A3Q1MRR6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1MRR6" } ] } ] }, { "uniprot_ac": "A0A3Q1MRW3", "gene_name": "SNRK", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A3Q1MRW3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1MRW3" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A3Q1MRW3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1MRW3" } ] } ] }, { "uniprot_ac": "A0A3Q1MS69", "gene_name": "NEK2", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A3Q1MS69", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1MS69" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A3Q1MS69", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1MS69" } ] } ] }, { "uniprot_ac": "A0A3Q1MUZ6", "gene_name": "MARK4", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A3Q1MUZ6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1MUZ6" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A3Q1MUZ6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1MUZ6" } ] } ] }, { "uniprot_ac": "A0A3Q1MW77", "gene_name": "ROCK2", "activity": [ { "ec_number": "2.7.11.39", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A3Q1MW77", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1MW77" } ] }, { "ec_number": "2.7.11.39", "activity": "", "evidence": [ { "id": "A0A3Q1MW77", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1MW77" } ] } ] }, { "uniprot_ac": "A0A3Q1MXI5", "gene_name": "DAPK1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A3Q1MXI5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1MXI5" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A3Q1MXI5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1MXI5" } ] } ] }, { "uniprot_ac": "A0A3Q1N4A7", "gene_name": "CIT", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A3Q1N4A7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1N4A7" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A3Q1N4A7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1N4A7" } ] } ] }, { "uniprot_ac": "A0A3Q1N707", "gene_name": "WNK4", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A3Q1N707", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1N707" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A3Q1N707", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1N707" } ] } ] }, { "uniprot_ac": "A0A3Q1N860", "gene_name": "RPS6KL1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A3Q1N860", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1N860" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A3Q1N860", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1N860" } ] } ] }, { "uniprot_ac": "A0A3Q1N9F5", "gene_name": "PRKD1", "activity": [ { "ec_number": "2.7.11.13", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A3Q1N9F5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1N9F5" } ] }, { "ec_number": "2.7.11.13", "activity": "", "evidence": [ { "id": "A0A3Q1N9F5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1N9F5" } ] } ] }, { "uniprot_ac": "A0A3Q1NBC4", "gene_name": "SRPK2", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A3Q1NBC4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1NBC4" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A3Q1NBC4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1NBC4" } ] } ] }, { "uniprot_ac": "A0A3Q1NFM1", "gene_name": "LOC100138998", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A3Q1NFM1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1NFM1" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A3Q1NFM1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1NFM1" } ] } ] }, { "uniprot_ac": "A0A3Q1NKC2", "gene_name": "CAMK2G", "activity": [ { "ec_number": "2.7.11.17", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A3Q1NKC2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1NKC2" } ] }, { "ec_number": "2.7.11.17", "activity": "", "evidence": [ { "id": "A0A3Q1NKC2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1NKC2" } ] } ] }, { "uniprot_ac": "A0A3S5ZPR2", "gene_name": "MELK", "activity": [ { "ec_number": "2.7.10.2", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A3S5ZPR2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3S5ZPR2" } ] }, { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A3S5ZPR2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3S5ZPR2" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A3S5ZPR2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3S5ZPR2" } ] }, { "ec_number": "2.7.10.2", "activity": "", "evidence": [ { "id": "A0A3S5ZPR2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3S5ZPR2" } ] } ] }, { "uniprot_ac": "A0AAA9RSJ2", "gene_name": "MKNK2", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0AAA9RSJ2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9RSJ2" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0AAA9RSJ2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9RSJ2" } ] } ] }, { "uniprot_ac": "A0AAA9RSQ6", "gene_name": "TRPM6", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0AAA9RSQ6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9RSQ6" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0AAA9RSQ6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9RSQ6" } ] } ] }, { "uniprot_ac": "A0AAA9RTJ4", "gene_name": "PIKFYVE", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0AAA9RTJ4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9RTJ4" } ] }, { "ec_number": "2.7.1.150", "activity": "a 1,2-diacyl-sn-glycero-3-phospho-(1D-myo-inositol-3-phosphate) + ATP = a 1,2-diacyl-sn-glycero-3-phospho-(1D-myo-inositol-3,5-bisphosphate) + ADP + H(+).", "evidence": [ { "id": "A0AAA9RTJ4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9RTJ4" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0AAA9RTJ4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9RTJ4" } ] }, { "ec_number": "2.7.1.150", "activity": "", "evidence": [ { "id": "A0AAA9RTJ4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9RTJ4" } ] } ] }, { "uniprot_ac": "A0AAA9RVB1", "gene_name": "TAOK2", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0AAA9RVB1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9RVB1" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0AAA9RVB1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9RVB1" } ] } ] }, { "uniprot_ac": "A0AAA9RW51", "gene_name": "AATK", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0AAA9RW51", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9RW51" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0AAA9RW51", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9RW51" } ] } ] }, { "uniprot_ac": "A0AAA9RWB8", "gene_name": "TRIO", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0AAA9RWB8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9RWB8" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0AAA9RWB8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9RWB8" } ] } ] }, { "uniprot_ac": "A0AAA9RWC6", "gene_name": "CHEK2", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0AAA9RWC6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9RWC6" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0AAA9RWC6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9RWC6" } ] } ] }, { "uniprot_ac": "A0AAA9S2N3", "gene_name": "CDKL4", "activity": [ { "ec_number": "2.7.11.22", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0AAA9S2N3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9S2N3" } ] }, { "ec_number": "2.7.11.22", "activity": "", "evidence": [ { "id": "A0AAA9S2N3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9S2N3" } ] } ] }, { "uniprot_ac": "A0AAA9S472", "gene_name": "MAPK8", "activity": [ { "ec_number": "2.7.11.24", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0AAA9S472", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9S472" } ] }, { "ec_number": "2.7.11.24", "activity": "", "evidence": [ { "id": "A0AAA9S472", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9S472" } ] } ] }, { "uniprot_ac": "A0AAA9S4Z4", "gene_name": "AKT1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0AAA9S4Z4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9S4Z4" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0AAA9S4Z4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9S4Z4" } ] } ] }, { "uniprot_ac": "A0AAA9S5X7", "gene_name": "AURKB", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0AAA9S5X7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9S5X7" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0AAA9S5X7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9S5X7" } ] } ] }, { "uniprot_ac": "A0AAA9S663", "gene_name": "PDPK1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0AAA9S663", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9S663" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0AAA9S663", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9S663" } ] } ] }, { "uniprot_ac": "A0AAA9S954", "gene_name": "CAMKK1", "activity": [ { "ec_number": "2.7.11.17", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0AAA9S954", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9S954" } ] }, { "ec_number": "2.7.11.17", "activity": "", "evidence": [ { "id": "A0AAA9S954", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9S954" } ] } ] }, { "uniprot_ac": "A0AAA9S9A9", "gene_name": "NEK11", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0AAA9S9A9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9S9A9" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0AAA9S9A9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9S9A9" } ] } ] }, { "uniprot_ac": "A0AAA9SG01", "gene_name": "ERN1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0AAA9SG01", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9SG01" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0AAA9SG01", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9SG01" } ] } ] }, { "uniprot_ac": "A0AAA9SGM8", "gene_name": "MKNK1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0AAA9SGM8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9SGM8" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0AAA9SGM8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9SGM8" } ] } ] }, { "uniprot_ac": "A0AAA9SH90", "gene_name": "DAPK2", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0AAA9SH90", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9SH90" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0AAA9SH90", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9SH90" } ] } ] }, { "uniprot_ac": "A0AAA9SIK7", "gene_name": "NEK10", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0AAA9SIK7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9SIK7" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0AAA9SIK7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9SIK7" } ] } ] }, { "uniprot_ac": "A0AAA9SJ92", "gene_name": "RPS6KA1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0AAA9SJ92", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9SJ92" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0AAA9SJ92", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9SJ92" } ] } ] }, { "uniprot_ac": "A0AAA9SJA3", "gene_name": "TTBK2", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0AAA9SJA3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9SJA3" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0AAA9SJA3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9SJA3" } ] } ] }, { "uniprot_ac": "A0AAA9SJQ0", "gene_name": "RPS6KA4", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0AAA9SJQ0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9SJQ0" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0AAA9SJQ0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9SJQ0" } ] } ] }, { "uniprot_ac": "A0AAA9SK35", "gene_name": "PRKG2", "activity": [ { "ec_number": "2.7.11.12", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0AAA9SK35", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9SK35" } ] }, { "ec_number": "2.7.11.12", "activity": "", "evidence": [ { "id": "A0AAA9SK35", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9SK35" } ] } ] }, { "uniprot_ac": "A0AAA9SKK8", "gene_name": "MAP3K4", "activity": [ { "ec_number": "2.7.11.25", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0AAA9SKK8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9SKK8" } ] }, { "ec_number": "2.7.11.25", "activity": "", "evidence": [ { "id": "A0AAA9SKK8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9SKK8" } ] } ] }, { "uniprot_ac": "A0AAA9SLY1", "gene_name": "NEK5", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0AAA9SLY1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9SLY1" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0AAA9SLY1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9SLY1" } ] } ] }, { "uniprot_ac": "A0AAA9SMH0", "gene_name": "DCLK3", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0AAA9SMH0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9SMH0" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0AAA9SMH0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9SMH0" } ] } ] }, { "uniprot_ac": "A0AAA9SMT9", "gene_name": "MAP3K12", "activity": [ { "ec_number": "2.7.11.25", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0AAA9SMT9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9SMT9" } ] }, { "ec_number": "2.7.11.25", "activity": "", "evidence": [ { "id": "A0AAA9SMT9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9SMT9" } ] } ] }, { "uniprot_ac": "A0AAA9SNP6", "gene_name": "MOS", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0AAA9SNP6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9SNP6" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0AAA9SNP6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9SNP6" } ] } ] }, { "uniprot_ac": "A0AAA9SU81", "gene_name": "PRKAA2", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0AAA9SU81", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9SU81" } ] }, { "ec_number": "2.7.11.31", "activity": "L-seryl-[acetyl-CoA carboxylase] + ATP = O-phospho-L-seryl-[acetyl-CoA carboxylase] + ADP + H(+).", "evidence": [ { "id": "A0AAA9SU81", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9SU81" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0AAA9SU81", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9SU81" } ] }, { "ec_number": "2.7.11.31", "activity": "", "evidence": [ { "id": "A0AAA9SU81", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9SU81" } ] } ] }, { "uniprot_ac": "A0AAA9SVM5", "gene_name": "MAP3K3", "activity": [ { "ec_number": "2.7.11.25", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0AAA9SVM5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9SVM5" } ] }, { "ec_number": "2.7.11.25", "activity": "", "evidence": [ { "id": "A0AAA9SVM5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9SVM5" } ] } ] }, { "uniprot_ac": "A0AAA9SWA1", "gene_name": "STK26", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0AAA9SWA1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9SWA1" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0AAA9SWA1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9SWA1" } ] } ] }, { "uniprot_ac": "A0AAA9SX77", "gene_name": "CDK14", "activity": [ { "ec_number": "2.7.11.22", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0AAA9SX77", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9SX77" } ] }, { "ec_number": "2.7.11.22", "activity": "", "evidence": [ { "id": "A0AAA9SX77", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9SX77" } ] } ] }, { "uniprot_ac": "A0AAA9SXE3", "gene_name": "MAP3K6", "activity": [ { "ec_number": "2.7.11.25", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0AAA9SXE3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9SXE3" } ] }, { "ec_number": "2.7.11.25", "activity": "", "evidence": [ { "id": "A0AAA9SXE3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9SXE3" } ] } ] }, { "uniprot_ac": "A0AAA9SYW5", "gene_name": "NEK3", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0AAA9SYW5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9SYW5" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0AAA9SYW5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9SYW5" } ] } ] }, { "uniprot_ac": "A0AAA9T042", "gene_name": "DYRK4", "activity": [ { "ec_number": "2.7.12.1", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0AAA9T042", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9T042" } ] }, { "ec_number": "2.7.12.1", "activity": "", "evidence": [ { "id": "A0AAA9T042", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9T042" } ] } ] }, { "uniprot_ac": "A0AAA9T2F0", "gene_name": "BRAF", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0AAA9T2F0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9T2F0" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0AAA9T2F0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9T2F0" } ] } ] }, { "uniprot_ac": "A0AAA9T3H7", "gene_name": "TNK1", "activity": [ { "ec_number": "2.7.10.2", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0AAA9T3H7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9T3H7" } ] }, { "ec_number": "2.7.10.2", "activity": "", "evidence": [ { "id": "A0AAA9T3H7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9T3H7" } ] } ] }, { "uniprot_ac": "A0AAA9T3K7", "gene_name": "WNK3", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0AAA9T3K7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9T3K7" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0AAA9T3K7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9T3K7" } ] } ] }, { "uniprot_ac": "A0AAA9T584", "gene_name": "CSNK1G3", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0AAA9T584", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9T584" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0AAA9T584", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9T584" } ] } ] }, { "uniprot_ac": "A0AAA9T593", "gene_name": "SRPK1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0AAA9T593", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9T593" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0AAA9T593", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9T593" } ] } ] }, { "uniprot_ac": "A0AAA9T5C9", "gene_name": "MAPK1", "activity": [ { "ec_number": "2.7.11.24", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0AAA9T5C9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9T5C9" } ] }, { "ec_number": "2.7.11.24", "activity": "", "evidence": [ { "id": "A0AAA9T5C9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9T5C9" } ] } ] }, { "uniprot_ac": "A0AAA9T7I8", "gene_name": "TSSK2", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0AAA9T7I8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9T7I8" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0AAA9T7I8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9T7I8" } ] } ] }, { "uniprot_ac": "A0AAA9T7L6", "gene_name": "RPS6KC1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0AAA9T7L6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9T7L6" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0AAA9T7L6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9T7L6" } ] } ] }, { "uniprot_ac": "A0AAA9T7Z7", "gene_name": "RPS6KA5", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0AAA9T7Z7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9T7Z7" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0AAA9T7Z7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9T7Z7" } ] } ] }, { "uniprot_ac": "A0AAA9T8T9", "gene_name": "MARK2", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0AAA9T8T9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9T8T9" } ] }, { "ec_number": "2.7.11.26", "activity": "L-seryl-[tau protein] + ATP = O-phospho-L-seryl-[tau protein] + ADP + H(+).", "evidence": [ { "id": "A0AAA9T8T9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9T8T9" } ] }, { "ec_number": "2.7.11.26", "activity": "", "evidence": [ { "id": "A0AAA9T8T9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9T8T9" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0AAA9T8T9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9T8T9" } ] } ] }, { "uniprot_ac": "A0AAA9T8Z3", "gene_name": "STK32C", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0AAA9T8Z3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9T8Z3" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0AAA9T8Z3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9T8Z3" } ] } ] }, { "uniprot_ac": "A0AAA9T940", "gene_name": "PLK2", "activity": [ { "ec_number": "2.7.11.21", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0AAA9T940", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9T940" } ] }, { "ec_number": "2.7.11.21", "activity": "", "evidence": [ { "id": "A0AAA9T940", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9T940" } ] } ] }, { "uniprot_ac": "A0AAA9TCI9", "gene_name": "MOK", "activity": [ { "ec_number": "2.7.11.22", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0AAA9TCI9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TCI9" } ] }, { "ec_number": "2.7.11.22", "activity": "", "evidence": [ { "id": "A0AAA9TCI9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TCI9" } ] } ] }, { "uniprot_ac": "A0AAA9TD48", "gene_name": "DYRK1B", "activity": [ { "ec_number": "2.7.12.1", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0AAA9TD48", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TD48" } ] }, { "ec_number": "2.7.12.1", "activity": "", "evidence": [ { "id": "A0AAA9TD48", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TD48" } ] } ] }, { "uniprot_ac": "A0AAA9TDL1", "gene_name": "SBK1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0AAA9TDL1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TDL1" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0AAA9TDL1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TDL1" } ] } ] }, { "uniprot_ac": "A0AAA9TJD5", "gene_name": "", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0AAA9TJD5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TJD5" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0AAA9TJD5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TJD5" } ] } ] }, { "uniprot_ac": "A0AAA9TLV0", "gene_name": "STK32B", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0AAA9TLV0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TLV0" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0AAA9TLV0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TLV0" } ] } ] }, { "uniprot_ac": "A0AAA9TMV7", "gene_name": "SMG1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0AAA9TMV7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TMV7" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0AAA9TMV7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TMV7" } ] } ] }, { "uniprot_ac": "A0AAA9TNE6", "gene_name": "TLK2", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0AAA9TNE6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TNE6" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0AAA9TNE6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TNE6" } ] } ] }, { "uniprot_ac": "A0AAA9TNL3", "gene_name": "SLK", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0AAA9TNL3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TNL3" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0AAA9TNL3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TNL3" } ] } ] }, { "uniprot_ac": "A0AAA9TP92", "gene_name": "CAMK1", "activity": [ { "ec_number": "2.7.11.17", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0AAA9TP92", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TP92" } ] }, { "ec_number": "2.7.11.17", "activity": "", "evidence": [ { "id": "A0AAA9TP92", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TP92" } ] } ] }, { "uniprot_ac": "A0AAA9TU12", "gene_name": "PRKCQ", "activity": [ { "ec_number": "2.7.11.13", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0AAA9TU12", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TU12" } ] }, { "ec_number": "2.7.11.13", "activity": "", "evidence": [ { "id": "A0AAA9TU12", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TU12" } ] } ] }, { "uniprot_ac": "A0AAA9TVT5", "gene_name": "CASK", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0AAA9TVT5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TVT5" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0AAA9TVT5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TVT5" } ] } ] }, { "uniprot_ac": "A0AAA9TWW0", "gene_name": "TBK1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0AAA9TWW0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TWW0" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0AAA9TWW0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TWW0" } ] } ] }, { "uniprot_ac": "A0AAA9U136", "gene_name": "PRKD2", "activity": [ { "ec_number": "2.7.11.13", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0AAA9U136", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9U136" } ] }, { "ec_number": "2.7.11.13", "activity": "", "evidence": [ { "id": "A0AAA9U136", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9U136" } ] } ] }, { "uniprot_ac": "A0AAA9U1A4", "gene_name": "NUAK2", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0AAA9U1A4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9U1A4" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0AAA9U1A4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9U1A4" } ] } ] }, { "uniprot_ac": "A0AAA9U1M9", "gene_name": "DMPK", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0AAA9U1M9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9U1M9" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0AAA9U1M9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9U1M9" } ] } ] }, { "uniprot_ac": "A0AAA9U1R3", "gene_name": "DCLK2", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0AAA9U1R3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9U1R3" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0AAA9U1R3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9U1R3" } ] } ] }, { "uniprot_ac": "A0AAF6DLR2", "gene_name": "CDK18", "activity": [ { "ec_number": "2.7.11.22", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0AAF6DLR2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAF6DLR2" } ] }, { "ec_number": "2.7.11.22", "activity": "", "evidence": [ { "id": "A0AAF6DLR2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAF6DLR2" } ] } ] }, { "uniprot_ac": "A0AAF6DMH7", "gene_name": "RIPK1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0AAF6DMH7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAF6DMH7" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0AAF6DMH7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAF6DMH7" } ] } ] }, { "uniprot_ac": "A0AAF6YHL8", "gene_name": "MAPK7", "activity": [ { "ec_number": "2.7.11.24", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0AAF6YHL8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAF6YHL8" } ] }, { "ec_number": "2.7.11.24", "activity": "", "evidence": [ { "id": "A0AAF6YHL8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAF6YHL8" } ] } ] }, { "uniprot_ac": "A0AAF6YMX3", "gene_name": "CDK9", "activity": [ { "ec_number": "2.7.11.22", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0AAF6YMX3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAF6YMX3" } ] }, { "ec_number": "2.7.11.23", "activity": "[DNA-directed RNA polymerase] + ATP = phospho-[DNA-directed RNA polymerase] + ADP + H(+).", "evidence": [ { "id": "A0AAF6YMX3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAF6YMX3" } ] }, { "ec_number": "2.7.11.22", "activity": "", "evidence": [ { "id": "A0AAF6YMX3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAF6YMX3" } ] }, { "ec_number": "2.7.11.23", "activity": "", "evidence": [ { "id": "A0AAF6YMX3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAF6YMX3" } ] } ] }, { "uniprot_ac": "A0AAF6Z257", "gene_name": "IRAK1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0AAF6Z257", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAF6Z257" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0AAF6Z257", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAF6Z257" } ] } ] }, { "uniprot_ac": "A0ABI0NJ75", "gene_name": "PAK6", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0ABI0NJ75", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NJ75" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0ABI0NJ75", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NJ75" } ] } ] }, { "uniprot_ac": "A0ABI0NM98", "gene_name": "KALRN", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0ABI0NM98", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NM98" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0ABI0NM98", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NM98" } ] } ] }, { "uniprot_ac": "A0ABI0NMT8", "gene_name": "PIK3CG", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0ABI0NMT8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NMT8" } ] }, { "ec_number": "2.7.1.153", "activity": "a 1,2-diacyl-sn-glycero-3-phospho-(1D-myo-inositol-4,5-bisphosphate) + ATP = a 1,2-diacyl-sn-glycero-3-phospho-(1D-myo-inositol-3,4,5-trisphosphate) + ADP + H(+).", "evidence": [ { "id": "A0ABI0NMT8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NMT8" } ] }, { "ec_number": "2.7.1.137", "activity": "a 1,2-diacyl-sn-glycero-3-phospho-(1D-myo-inositol) + ATP = a 1,2-diacyl-sn-glycero-3-phospho-(1D-myo-inositol-3-phosphate) + ADP + H(+).", "evidence": [ { "id": "A0ABI0NMT8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NMT8" } ] }, { "ec_number": "2.7.1.154", "activity": "a 1,2-diacyl-sn-glycero-3-phospho-(1D-myo-inositol 4-phosphate) + ATP = a 1,2-diacyl-sn-glycero-3-phospho-(1D-myo-inositol-3,4-bisphosphate) + ADP + H(+).", "evidence": [ { "id": "A0ABI0NMT8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NMT8" } ] }, { "ec_number": "2.7.1.153", "activity": "", "evidence": [ { "id": "A0ABI0NMT8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NMT8" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0ABI0NMT8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NMT8" } ] }, { "ec_number": "2.7.1.137", "activity": "", "evidence": [ { "id": "A0ABI0NMT8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NMT8" } ] }, { "ec_number": "2.7.1.154", "activity": "", "evidence": [ { "id": "A0ABI0NMT8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NMT8" } ] } ] }, { "uniprot_ac": "A0ABI0NQQ4", "gene_name": "PRKAA1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0ABI0NQQ4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NQQ4" } ] }, { "ec_number": "2.7.11.26", "activity": "L-seryl-[tau protein] + ATP = O-phospho-L-seryl-[tau protein] + ADP + H(+).", "evidence": [ { "id": "A0ABI0NQQ4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NQQ4" } ] }, { "ec_number": "2.7.11.31", "activity": "L-seryl-[acetyl-CoA carboxylase] + ATP = O-phospho-L-seryl-[acetyl-CoA carboxylase] + ADP + H(+).", "evidence": [ { "id": "A0ABI0NQQ4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NQQ4" } ] }, { "ec_number": "2.7.11.26", "activity": "", "evidence": [ { "id": "A0ABI0NQQ4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NQQ4" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0ABI0NQQ4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NQQ4" } ] }, { "ec_number": "2.7.11.31", "activity": "", "evidence": [ { "id": "A0ABI0NQQ4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NQQ4" } ] } ] }, { "uniprot_ac": "A0ABI0NRQ5", "gene_name": "LOC101905399", "activity": [ { "ec_number": "2.7.12.2", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0ABI0NRQ5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NRQ5" } ] }, { "ec_number": "2.7.12.2", "activity": "", "evidence": [ { "id": "A0ABI0NRQ5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NRQ5" } ] } ] }, { "uniprot_ac": "A0ABI0NS30", "gene_name": "PRKCA", "activity": [ { "ec_number": "2.7.11.13", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0ABI0NS30", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NS30" } ] }, { "ec_number": "2.7.11.13", "activity": "", "evidence": [ { "id": "A0ABI0NS30", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NS30" } ] } ] }, { "uniprot_ac": "A0ABI0NV47", "gene_name": "DCLK1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0ABI0NV47", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NV47" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0ABI0NV47", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NV47" } ] } ] }, { "uniprot_ac": "A0ABI0P0X3", "gene_name": "", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0ABI0P0X3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0ABI0P0X3" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0ABI0P0X3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0ABI0P0X3" } ] } ] }, { "uniprot_ac": "A0ABI0P2C0", "gene_name": "TSSK5", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0ABI0P2C0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0ABI0P2C0" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0ABI0P2C0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0ABI0P2C0" } ] } ] }, { "uniprot_ac": "A0ABI0P3N8", "gene_name": "", "activity": [ { "ec_number": "2.7.11.22", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0ABI0P3N8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0ABI0P3N8" } ] }, { "ec_number": "2.7.11.22", "activity": "", "evidence": [ { "id": "A0ABI0P3N8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0ABI0P3N8" } ] } ] }, { "uniprot_ac": "A0ABI0P3P6", "gene_name": "MAST4", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0ABI0P3P6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0ABI0P3P6" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0ABI0P3P6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0ABI0P3P6" } ] } ] }, { "uniprot_ac": "A0ABI0P443", "gene_name": "SGK2", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0ABI0P443", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0ABI0P443" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0ABI0P443", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0ABI0P443" } ] } ] }, { "uniprot_ac": "A1A4I4", "gene_name": "PKN1", "activity": [ { "ec_number": "2.7.11.13", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A1A4I4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A1A4I4" } ] }, { "ec_number": "2.7.11.13", "activity": "", "evidence": [ { "id": "A1A4I4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A1A4I4" } ] } ] }, { "uniprot_ac": "A2VDU3", "gene_name": "MAP3K7", "activity": [ { "ec_number": "2.7.11.25", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A2VDU3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A2VDU3" } ] }, { "ec_number": "2.7.11.25", "activity": "", "evidence": [ { "id": "A2VDU3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A2VDU3" } ] } ] }, { "uniprot_ac": "A2VDV2", "gene_name": "STK38", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A2VDV2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A2VDV2" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A2VDV2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A2VDV2" } ] } ] }, { "uniprot_ac": "A2VDZ4", "gene_name": "PLK4", "activity": [ { "ec_number": "2.7.11.21", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A2VDZ4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A2VDZ4" } ] }, { "ec_number": "2.7.11.21", "activity": "", "evidence": [ { "id": "A2VDZ4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A2VDZ4" } ] } ] }, { "uniprot_ac": "A5D791", "gene_name": "EIF2AK3", "activity": [ { "ec_number": "2.7.10.2", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "A5D791", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A5D791" } ] }, { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A5D791", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A5D791" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A5D791", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A5D791" } ] } ] }, { "uniprot_ac": "A5PKJ4", "gene_name": "MAPK7", "activity": [ { "ec_number": "2.7.11.24", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A5PKJ4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A5PKJ4" } ] }, { "ec_number": "2.7.11.24", "activity": "", "evidence": [ { "id": "A5PKJ4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A5PKJ4" } ] } ] }, { "uniprot_ac": "A7E3S4", "gene_name": "RAF1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A7E3S4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A7E3S4" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A7E3S4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A7E3S4" } ] } ] }, { "uniprot_ac": "A7E3X2", "gene_name": "CSNK1G1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A7E3X2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A7E3X2" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A7E3X2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A7E3X2" } ] } ] }, { "uniprot_ac": "A7MB74", "gene_name": "SGK1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A7MB74", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A7MB74" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A7MB74", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A7MB74" } ] } ] }, { "uniprot_ac": "A7MBB4", "gene_name": "MAP3K13", "activity": [ { "ec_number": "2.7.11.25", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A7MBB4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A7MBB4" } ] }, { "ec_number": "2.7.11.25", "activity": "", "evidence": [ { "id": "A7MBB4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A7MBB4" } ] } ] }, { "uniprot_ac": "E1B754", "gene_name": "MAST2", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "E1B754", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1B754" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "E1B754", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1B754" } ] } ] }, { "uniprot_ac": "E1B793", "gene_name": "STK36", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "E1B793", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1B793" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "E1B793", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1B793" } ] } ] }, { "uniprot_ac": "E1B7H4", "gene_name": "MAP3K10", "activity": [ { "ec_number": "2.7.11.25", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "E1B7H4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1B7H4" } ] }, { "ec_number": "2.7.11.25", "activity": "", "evidence": [ { "id": "E1B7H4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1B7H4" } ] } ] }, { "uniprot_ac": "E1B7L9", "gene_name": "PRKD3", "activity": [ { "ec_number": "2.7.11.13", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "E1B7L9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1B7L9" } ] }, { "ec_number": "2.7.11.13", "activity": "", "evidence": [ { "id": "E1B7L9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1B7L9" } ] } ] }, { "uniprot_ac": "E1B827", "gene_name": "NEK8", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "E1B827", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1B827" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "E1B827", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1B827" } ] } ] }, { "uniprot_ac": "E1B887", "gene_name": "RIOK1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "E1B887", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1B887" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "E1B887", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1B887" } ] } ] }, { "uniprot_ac": "E1B8J7", "gene_name": "ERN2", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "E1B8J7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1B8J7" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "E1B8J7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1B8J7" } ] } ] }, { "uniprot_ac": "E1B8P9", "gene_name": "MAPK3", "activity": [ { "ec_number": "2.7.11.24", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "E1B8P9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1B8P9" } ] }, { "ec_number": "2.7.11.24", "activity": "", "evidence": [ { "id": "E1B8P9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1B8P9" } ] } ] }, { "uniprot_ac": "E1B902", "gene_name": "MAP4K2", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "E1B902", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1B902" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "E1B902", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1B902" } ] } ] }, { "uniprot_ac": "E1B9B6", "gene_name": "NUAK1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "E1B9B6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1B9B6" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "E1B9B6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1B9B6" } ] } ] }, { "uniprot_ac": "E1B9F9", "gene_name": "LATS2", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "E1B9F9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1B9F9" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "E1B9F9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1B9F9" } ] } ] }, { "uniprot_ac": "E1B9Q2", "gene_name": "CLK2", "activity": [ { "ec_number": "2.7.12.1", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "E1B9Q2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1B9Q2" } ] }, { "ec_number": "2.7.12.1", "activity": "", "evidence": [ { "id": "E1B9Q2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1B9Q2" } ] } ] }, { "uniprot_ac": "E1BAL6", "gene_name": "EIF2AK4", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "E1BAL6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BAL6" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "E1BAL6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BAL6" } ] } ] }, { "uniprot_ac": "E1BB49", "gene_name": "HIPK4", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "E1BB49", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BB49" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "E1BB49", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BB49" } ] } ] }, { "uniprot_ac": "E1BB50", "gene_name": "CDK12", "activity": [ { "ec_number": "2.7.11.22", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "E1BB50", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BB50" } ] }, { "ec_number": "2.7.11.23", "activity": "[DNA-directed RNA polymerase] + ATP = phospho-[DNA-directed RNA polymerase] + ADP + H(+).", "evidence": [ { "id": "E1BB50", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BB50" } ] }, { "ec_number": "2.7.11.23", "activity": "", "evidence": [ { "id": "E1BB50", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BB50" } ] }, { "ec_number": "2.7.11.22", "activity": "", "evidence": [ { "id": "E1BB50", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BB50" } ] } ] }, { "uniprot_ac": "E1BB52", "gene_name": "CDK13", "activity": [ { "ec_number": "2.7.11.22", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "E1BB52", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BB52" } ] }, { "ec_number": "2.7.11.23", "activity": "[DNA-directed RNA polymerase] + ATP = phospho-[DNA-directed RNA polymerase] + ADP + H(+).", "evidence": [ { "id": "E1BB52", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BB52" } ] }, { "ec_number": "2.7.11.23", "activity": "", "evidence": [ { "id": "E1BB52", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BB52" } ] }, { "ec_number": "2.7.11.22", "activity": "", "evidence": [ { "id": "E1BB52", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BB52" } ] } ] }, { "uniprot_ac": "E1BBM3", "gene_name": "NEK1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "E1BBM3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BBM3" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "E1BBM3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BBM3" } ] } ] }, { "uniprot_ac": "E1BC36", "gene_name": "CDK6", "activity": [ { "ec_number": "2.7.11.22", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "E1BC36", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BC36" } ] }, { "ec_number": "2.7.11.22", "activity": "", "evidence": [ { "id": "E1BC36", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BC36" } ] } ] }, { "uniprot_ac": "E1BC64", "gene_name": "LIMK1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "E1BC64", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BC64" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "E1BC64", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BC64" } ] } ] }, { "uniprot_ac": "E1BC69", "gene_name": "HIPK3", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "E1BC69", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BC69" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "E1BC69", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BC69" } ] } ] }, { "uniprot_ac": "E1BCC3", "gene_name": "UHMK1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "E1BCC3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BCC3" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "E1BCC3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BCC3" } ] } ] }, { "uniprot_ac": "E1BCH5", "gene_name": "LATS1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "E1BCH5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BCH5" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "E1BCH5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BCH5" } ] } ] }, { "uniprot_ac": "E1BCU9", "gene_name": "STK11", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "E1BCU9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BCU9" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "E1BCU9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BCU9" } ] } ] }, { "uniprot_ac": "E1BDG4", "gene_name": "MAK", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "E1BDG4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BDG4" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "E1BDG4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BDG4" } ] } ] }, { "uniprot_ac": "E1BEI6", "gene_name": "ATM", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "E1BEI6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BEI6" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "E1BEI6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BEI6" } ] } ] }, { "uniprot_ac": "E1BEW4", "gene_name": "LOC613515", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "E1BEW4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BEW4" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "E1BEW4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BEW4" } ] } ] }, { "uniprot_ac": "E1BFR5", "gene_name": "MASTL", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "E1BFR5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BFR5" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "E1BFR5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BFR5" } ] } ] }, { "uniprot_ac": "E1BFV2", "gene_name": "MAP3K21", "activity": [ { "ec_number": "2.7.11.25", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "E1BFV2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BFV2" } ] }, { "ec_number": "2.7.11.25", "activity": "", "evidence": [ { "id": "E1BFV2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BFV2" } ] } ] }, { "uniprot_ac": "E1BG90", "gene_name": "DYRK2", "activity": [ { "ec_number": "2.7.12.1", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "E1BG90", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BG90" } ] }, { "ec_number": "2.7.12.1", "activity": "", "evidence": [ { "id": "E1BG90", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BG90" } ] } ] }, { "uniprot_ac": "E1BGV8", "gene_name": "MAP3K19", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "E1BGV8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BGV8" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "E1BGV8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BGV8" } ] } ] }, { "uniprot_ac": "E1BH31", "gene_name": "MAP4K1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "E1BH31", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BH31" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "E1BH31", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BH31" } ] } ] }, { "uniprot_ac": "E1BHE1", "gene_name": "TAOK3", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "E1BHE1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BHE1" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "E1BHE1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BHE1" } ] } ] }, { "uniprot_ac": "E1BI01", "gene_name": "MAP2K5", "activity": [ { "ec_number": "2.7.12.2", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "E1BI01", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BI01" } ] }, { "ec_number": "2.7.12.2", "activity": "", "evidence": [ { "id": "E1BI01", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BI01" } ] } ] }, { "uniprot_ac": "E1BI47", "gene_name": "PLK5", "activity": [ { "ec_number": "2.7.11.21", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "E1BI47", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BI47" } ] }, { "ec_number": "2.7.11.21", "activity": "", "evidence": [ { "id": "E1BI47", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BI47" } ] } ] }, { "uniprot_ac": "E1BJ19", "gene_name": "TAOK1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "E1BJ19", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BJ19" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "E1BJ19", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BJ19" } ] } ] }, { "uniprot_ac": "E1BJH5", "gene_name": "MAP4K3", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "E1BJH5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BJH5" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "E1BJH5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BJH5" } ] } ] }, { "uniprot_ac": "E1BJM5", "gene_name": "MTERF4", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "E1BJM5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BJM5" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "E1BJM5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BJM5" } ] } ] }, { "uniprot_ac": "E1BK33", "gene_name": "MAST1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "E1BK33", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BK33" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "E1BK33", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BK33" } ] } ] }, { "uniprot_ac": "E1BK52", "gene_name": "STK10", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "E1BK52", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BK52" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "E1BK52", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BK52" } ] } ] }, { "uniprot_ac": "E1BKX9", "gene_name": "CDKL5", "activity": [ { "ec_number": "2.7.11.22", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "E1BKX9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BKX9" } ] }, { "ec_number": "2.7.11.22", "activity": "", "evidence": [ { "id": "E1BKX9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BKX9" } ] } ] }, { "uniprot_ac": "E1BL08", "gene_name": "MAP3K14", "activity": [ { "ec_number": "2.7.11.25", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "E1BL08", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BL08" } ] }, { "ec_number": "2.7.11.25", "activity": "", "evidence": [ { "id": "E1BL08", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BL08" } ] } ] }, { "uniprot_ac": "E1BLQ5", "gene_name": "RPS6KB2", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "E1BLQ5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BLQ5" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "E1BLQ5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BLQ5" } ] } ] }, { "uniprot_ac": "E1BM19", "gene_name": "CDKL3", "activity": [ { "ec_number": "2.7.11.22", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "E1BM19", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BM19" } ] }, { "ec_number": "2.7.11.22", "activity": "", "evidence": [ { "id": "E1BM19", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BM19" } ] } ] }, { "uniprot_ac": "E1BMN8", "gene_name": "NLK", "activity": [ { "ec_number": "2.7.11.24", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "E1BMN8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BMN8" } ] }, { "ec_number": "2.7.11.24", "activity": "", "evidence": [ { "id": "E1BMN8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BMN8" } ] } ] }, { "uniprot_ac": "E1BN63", "gene_name": "WNK1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "E1BN63", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BN63" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "E1BN63", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BN63" } ] } ] }, { "uniprot_ac": "E1BN72", "gene_name": "NIM1K", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "E1BN72", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BN72" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "E1BN72", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BN72" } ] } ] }, { "uniprot_ac": "E1BNH0", "gene_name": "WNK2", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "E1BNH0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BNH0" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "E1BNH0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BNH0" } ] } ] }, { "uniprot_ac": "E1BNS8", "gene_name": "SIK1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "E1BNS8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BNS8" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "E1BNS8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BNS8" } ] } ] }, { "uniprot_ac": "E1BP01", "gene_name": "MYO3A", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "E1BP01", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BP01" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "E1BP01", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BP01" } ] } ] }, { "uniprot_ac": "E1BP72", "gene_name": "CDC42BPB", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "E1BP72", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BP72" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "E1BP72", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BP72" } ] } ] }, { "uniprot_ac": "E1BPB5", "gene_name": "TESK1", "activity": [ { "ec_number": "2.7.12.1", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "E1BPB5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BPB5" } ] }, { "ec_number": "2.7.12.1", "activity": "", "evidence": [ { "id": "E1BPB5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BPB5" } ] } ] }, { "uniprot_ac": "E1BPP1", "gene_name": "TTK", "activity": [ { "ec_number": "2.7.12.1", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "E1BPP1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BPP1" } ] }, { "ec_number": "2.7.12.1", "activity": "", "evidence": [ { "id": "E1BPP1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BPP1" } ] } ] }, { "uniprot_ac": "E1BPU0", "gene_name": "LRRK2", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "E1BPU0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BPU0" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "E1BPU0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BPU0" } ] } ] }, { "uniprot_ac": "E1BQ34", "gene_name": "HIPK1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "E1BQ34", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BQ34" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "E1BQ34", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BQ34" } ] } ] }, { "uniprot_ac": "F1MAZ8", "gene_name": "MARK3", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "F1MAZ8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MAZ8" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "F1MAZ8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MAZ8" } ] } ] }, { "uniprot_ac": "F1MBN7", "gene_name": "RIOK2", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "F1MBN7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MBN7" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "F1MBN7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MBN7" } ] } ] }, { "uniprot_ac": "F1MC27", "gene_name": "LMTK3", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "F1MC27", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MC27" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "F1MC27", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MC27" } ] } ] }, { "uniprot_ac": "F1MC61", "gene_name": "MAP3K11", "activity": [ { "ec_number": "2.7.11.25", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "F1MC61", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MC61" } ] }, { "ec_number": "2.7.11.25", "activity": "", "evidence": [ { "id": "F1MC61", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MC61" } ] } ] }, { "uniprot_ac": "F1MDC9", "gene_name": "PRKCE", "activity": [ { "ec_number": "2.7.11.13", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "F1MDC9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MDC9" } ] }, { "ec_number": "2.7.11.13", "activity": "", "evidence": [ { "id": "F1MDC9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MDC9" } ] } ] }, { "uniprot_ac": "F1MDS3", "gene_name": "PCK2", "activity": [ { "ec_number": "4.1.1.32", "activity": "ITP + oxaloacetate = IDP + phosphoenolpyruvate + CO2.", "evidence": [ { "id": "F1MDS3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MDS3" } ] }, { "ec_number": "4.1.1.32", "activity": "", "evidence": [ { "id": "F1MDS3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MDS3" } ] } ] }, { "uniprot_ac": "F1MF36", "gene_name": "KSR2", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "F1MF36", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MF36" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "F1MF36", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MF36" } ] } ] }, { "uniprot_ac": "F1MF50", "gene_name": "ROCK1", "activity": [ { "ec_number": "2.7.11.39", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "F1MF50", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MF50" } ] }, { "ec_number": "2.7.11.39", "activity": "", "evidence": [ { "id": "F1MF50", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MF50" } ] } ] }, { "uniprot_ac": "F1MFK1", "gene_name": "PKN2", "activity": [ { "ec_number": "2.7.11.13", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "F1MFK1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MFK1" } ] }, { "ec_number": "2.7.11.13", "activity": "", "evidence": [ { "id": "F1MFK1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MFK1" } ] } ] }, { "uniprot_ac": "F1MG29", "gene_name": "TSSK3", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "F1MG29", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MG29" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "F1MG29", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MG29" } ] } ] }, { "uniprot_ac": "F1MG35", "gene_name": "CIITA", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "F1MG35", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MG35" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "F1MG35", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MG35" } ] } ] }, { "uniprot_ac": "F1MG77", "gene_name": "HASPIN", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "F1MG77", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MG77" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "F1MG77", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MG77" } ] } ] }, { "uniprot_ac": "F1MGX2", "gene_name": "MAP3K13", "activity": [ { "ec_number": "2.7.11.25", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "F1MGX2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MGX2" } ] }, { "ec_number": "2.7.11.25", "activity": "", "evidence": [ { "id": "F1MGX2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MGX2" } ] } ] }, { "uniprot_ac": "F1MH23", "gene_name": "MAPKAPK5", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "F1MH23", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MH23" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "F1MH23", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MH23" } ] } ] }, { "uniprot_ac": "F1MH24", "gene_name": "AAK1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "F1MH24", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MH24" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "F1MH24", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MH24" } ] } ] }, { "uniprot_ac": "F1MH45", "gene_name": "CDC42BPA", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "F1MH45", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MH45" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "F1MH45", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MH45" } ] } ] }, { "uniprot_ac": "F1MI60", "gene_name": "MAP4K4", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "F1MI60", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MI60" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "F1MI60", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MI60" } ] } ] }, { "uniprot_ac": "F1MIB2", "gene_name": "GAK", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "F1MIB2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MIB2" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "F1MIB2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MIB2" } ] } ] }, { "uniprot_ac": "F1MJ55", "gene_name": "CSNK2A2", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "F1MJ55", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MJ55" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "F1MJ55", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MJ55" } ] } ] }, { "uniprot_ac": "F1MKK7", "gene_name": "PKMYT1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "F1MKK7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MKK7" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "F1MKK7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MKK7" } ] } ] }, { "uniprot_ac": "F1MKW8", "gene_name": "SIK2", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "F1MKW8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MKW8" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "F1MKW8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MKW8" } ] } ] }, { "uniprot_ac": "F1MKY9", "gene_name": "ALPK2", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "F1MKY9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MKY9" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "F1MKY9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MKY9" } ] } ] }, { "uniprot_ac": "F1MLY7", "gene_name": "ATR", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "F1MLY7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MLY7" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "F1MLY7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MLY7" } ] } ] }, { "uniprot_ac": "F1MM88", "gene_name": "NEK9", "activity": [ { "ec_number": "2.7.11.38", "activity": "L-threonyl-[protein] + ATP = O-phospho-L-threonyl-[protein] + ADP + H(+).", "evidence": [ { "id": "F1MM88", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MM88" } ] }, { "ec_number": "2.7.11.38", "activity": "", "evidence": [ { "id": "F1MM88", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MM88" } ] } ] }, { "uniprot_ac": "F1MN35", "gene_name": "PDIK1L", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "F1MN35", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MN35" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "F1MN35", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MN35" } ] } ] }, { "uniprot_ac": "F1MNP4", "gene_name": "RPS6KB1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "F1MNP4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MNP4" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "F1MNP4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MNP4" } ] } ] }, { "uniprot_ac": "F1MPF0", "gene_name": "TRPM7", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "F1MPF0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MPF0" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "F1MPF0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MPF0" } ] } ] }, { "uniprot_ac": "F1MPI8", "gene_name": "CDK8", "activity": [ { "ec_number": "2.7.11.22", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "F1MPI8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MPI8" } ] }, { "ec_number": "2.7.11.23", "activity": "[DNA-directed RNA polymerase] + ATP = phospho-[DNA-directed RNA polymerase] + ADP + H(+).", "evidence": [ { "id": "F1MPI8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MPI8" } ] }, { "ec_number": "2.7.11.22", "activity": "", "evidence": [ { "id": "F1MPI8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MPI8" } ] }, { "ec_number": "2.7.11.23", "activity": "", "evidence": [ { "id": "F1MPI8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MPI8" } ] } ] }, { "uniprot_ac": "F1MQ96", "gene_name": "PRKCI", "activity": [ { "ec_number": "2.7.11.13", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "F1MQ96", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MQ96" } ] }, { "ec_number": "2.7.11.13", "activity": "", "evidence": [ { "id": "F1MQ96", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MQ96" } ] } ] }, { "uniprot_ac": "F1MSI1", "gene_name": "STK17B", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "F1MSI1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MSI1" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "F1MSI1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MSI1" } ] } ] }, { "uniprot_ac": "F1MSV4", "gene_name": "SGK3", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "F1MSV4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MSV4" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "F1MSV4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MSV4" } ] } ] }, { "uniprot_ac": "F1MSX4", "gene_name": "MAP3K2", "activity": [ { "ec_number": "2.7.11.25", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "F1MSX4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MSX4" } ] }, { "ec_number": "2.7.11.25", "activity": "", "evidence": [ { "id": "F1MSX4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MSX4" } ] } ] }, { "uniprot_ac": "F1MU35", "gene_name": "PRKCG", "activity": [ { "ec_number": "2.7.11.13", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "F1MU35", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MU35" } ] }, { "ec_number": "2.7.11.13", "activity": "", "evidence": [ { "id": "F1MU35", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MU35" } ] } ] }, { "uniprot_ac": "F1MUU2", "gene_name": "STK35", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "F1MUU2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MUU2" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "F1MUU2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MUU2" } ] } ] }, { "uniprot_ac": "F1MVR0", "gene_name": "CDK19", "activity": [ { "ec_number": "2.7.11.22", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "F1MVR0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MVR0" } ] }, { "ec_number": "2.7.11.22", "activity": "", "evidence": [ { "id": "F1MVR0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MVR0" } ] } ] }, { "uniprot_ac": "F1MVV5", "gene_name": "MAPK4", "activity": [ { "ec_number": "2.7.11.24", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "F1MVV5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MVV5" } ] }, { "ec_number": "2.7.11.24", "activity": "", "evidence": [ { "id": "F1MVV5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MVV5" } ] } ] }, { "uniprot_ac": "F1MWN0", "gene_name": "EIF2AK1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "F1MWN0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MWN0" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "F1MWN0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MWN0" } ] } ] }, { "uniprot_ac": "F1MWP1", "gene_name": "BUB1B", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "F1MWP1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MWP1" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "F1MWP1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MWP1" } ] } ] }, { "uniprot_ac": "F1MXH6", "gene_name": "MAP3K5", "activity": [ { "ec_number": "2.7.11.25", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "F1MXH6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MXH6" } ] }, { "ec_number": "2.7.11.25", "activity": "", "evidence": [ { "id": "F1MXH6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MXH6" } ] } ] }, { "uniprot_ac": "F1MY55", "gene_name": "PAK5", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "F1MY55", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MY55" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "F1MY55", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MY55" } ] } ] }, { "uniprot_ac": "F1MY82", "gene_name": "PRKCH", "activity": [ { "ec_number": "2.7.11.13", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "F1MY82", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MY82" } ] }, { "ec_number": "2.7.11.13", "activity": "", "evidence": [ { "id": "F1MY82", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MY82" } ] } ] }, { "uniprot_ac": "F1MY86", "gene_name": "AURKC", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "F1MY86", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MY86" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "F1MY86", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MY86" } ] } ] }, { "uniprot_ac": "F1MYG2", "gene_name": "TLK1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "F1MYG2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MYG2" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "F1MYG2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MYG2" } ] } ] }, { "uniprot_ac": "F1MYM3", "gene_name": "PIK3CB", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "F1MYM3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MYM3" } ] }, { "ec_number": "2.7.1.153", "activity": "a 1,2-diacyl-sn-glycero-3-phospho-(1D-myo-inositol-4,5-bisphosphate) + ATP = a 1,2-diacyl-sn-glycero-3-phospho-(1D-myo-inositol-3,4,5-trisphosphate) + ADP + H(+).", "evidence": [ { "id": "F1MYM3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MYM3" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "F1MYM3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MYM3" } ] }, { "ec_number": "2.7.1.153", "activity": "", "evidence": [ { "id": "F1MYM3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MYM3" } ] } ] }, { "uniprot_ac": "F1MYV9", "gene_name": "OXSR1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "F1MYV9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MYV9" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "F1MYV9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MYV9" } ] } ] }, { "uniprot_ac": "F1N063", "gene_name": "CAMK1D", "activity": [ { "ec_number": "2.7.11.17", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "F1N063", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1N063" } ] }, { "ec_number": "2.7.11.17", "activity": "", "evidence": [ { "id": "F1N063", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1N063" } ] } ] }, { "uniprot_ac": "F1N2S7", "gene_name": "TSSK6", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "F1N2S7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1N2S7" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "F1N2S7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1N2S7" } ] } ] }, { "uniprot_ac": "F1N332", "gene_name": "ULK3", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "F1N332", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1N332" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "F1N332", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1N332" } ] } ] }, { "uniprot_ac": "F1N3W6", "gene_name": "MAP3K15", "activity": [ { "ec_number": "2.7.11.25", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "F1N3W6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1N3W6" } ] }, { "ec_number": "2.7.11.25", "activity": "", "evidence": [ { "id": "F1N3W6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1N3W6" } ] } ] }, { "uniprot_ac": "F1N5K1", "gene_name": "CDK11B", "activity": [ { "ec_number": "2.7.11.22", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "F1N5K1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1N5K1" } ] }, { "ec_number": "2.7.11.23", "activity": "[DNA-directed RNA polymerase] + ATP = phospho-[DNA-directed RNA polymerase] + ADP + H(+).", "evidence": [ { "id": "F1N5K1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1N5K1" } ] }, { "ec_number": "2.7.11.23", "activity": "", "evidence": [ { "id": "F1N5K1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1N5K1" } ] }, { "ec_number": "2.7.11.22", "activity": "", "evidence": [ { "id": "F1N5K1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1N5K1" } ] } ] }, { "uniprot_ac": "F1N5U0", "gene_name": "ALPK3", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "F1N5U0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1N5U0" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "F1N5U0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1N5U0" } ] } ] }, { "uniprot_ac": "F1N664", "gene_name": "MAP2K7", "activity": [ { "ec_number": "2.7.12.2", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "F1N664", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1N664" } ] }, { "ec_number": "2.7.12.2", "activity": "", "evidence": [ { "id": "F1N664", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1N664" } ] } ] }, { "uniprot_ac": "F1N6C1", "gene_name": "LRRK1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "F1N6C1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1N6C1" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "F1N6C1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1N6C1" } ] } ] }, { "uniprot_ac": "F6PN06", "gene_name": "TNK2", "activity": [ { "ec_number": "2.7.10.2", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "F6PN06", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F6PN06" } ] }, { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "F6PN06", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F6PN06" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "F6PN06", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F6PN06" } ] }, { "ec_number": "2.7.10.2", "activity": "", "evidence": [ { "id": "F6PN06", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F6PN06" } ] } ] }, { "uniprot_ac": "F6Q5B6", "gene_name": "EIF2AK2", "activity": [ { "ec_number": "2.7.10.2", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "F6Q5B6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F6Q5B6" } ] }, { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "F6Q5B6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F6Q5B6" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "F6Q5B6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F6Q5B6" } ] }, { "ec_number": "2.7.10.2", "activity": "", "evidence": [ { "id": "F6Q5B6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F6Q5B6" } ] } ] }, { "uniprot_ac": "F6Q5Z6", "gene_name": "BUB1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "F6Q5Z6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F6Q5Z6" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "F6Q5Z6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F6Q5Z6" } ] } ] }, { "uniprot_ac": "F6Q6K1", "gene_name": "CHEK1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "F6Q6K1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F6Q6K1" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "F6Q6K1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F6Q6K1" } ] } ] }, { "uniprot_ac": "F6Q9U9", "gene_name": "PNCK", "activity": [ { "ec_number": "2.7.11.17", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "F6Q9U9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F6Q9U9" } ] }, { "ec_number": "2.7.11.17", "activity": "", "evidence": [ { "id": "F6Q9U9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F6Q9U9" } ] } ] }, { "uniprot_ac": "F6QTX4", "gene_name": "RIPK3", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "F6QTX4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F6QTX4" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "F6QTX4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F6QTX4" } ] } ] }, { "uniprot_ac": "F6QVY2", "gene_name": "CDK20", "activity": [ { "ec_number": "2.7.11.22", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "F6QVY2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F6QVY2" } ] }, { "ec_number": "2.7.11.22", "activity": "", "evidence": [ { "id": "F6QVY2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F6QVY2" } ] } ] }, { "uniprot_ac": "F6QY93", "gene_name": "CDK3", "activity": [ { "ec_number": "2.7.11.22", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "F6QY93", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F6QY93" } ] }, { "ec_number": "2.7.11.22", "activity": "", "evidence": [ { "id": "F6QY93", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F6QY93" } ] } ] }, { "uniprot_ac": "F6RD87", "gene_name": "SRPK3", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "F6RD87", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F6RD87" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "F6RD87", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F6RD87" } ] } ] }, { "uniprot_ac": "F6RG88", "gene_name": "NEK4", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "F6RG88", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F6RG88" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "F6RG88", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F6RG88" } ] } ] }, { "uniprot_ac": "F6RLA2", "gene_name": "TSSK4", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "F6RLA2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F6RLA2" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "F6RLA2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F6RLA2" } ] } ] }, { "uniprot_ac": "F6RP02", "gene_name": "PIM2", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "F6RP02", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F6RP02" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "F6RP02", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F6RP02" } ] } ] }, { "uniprot_ac": "F6RPH3", "gene_name": "MAPK13", "activity": [ { "ec_number": "2.7.11.24", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "F6RPH3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F6RPH3" } ] }, { "ec_number": "2.7.11.24", "activity": "", "evidence": [ { "id": "F6RPH3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F6RPH3" } ] } ] }, { "uniprot_ac": "G3MX00", "gene_name": "", "activity": [ { "ec_number": "2.7.11.22", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "G3MX00", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3MX00" } ] }, { "ec_number": "2.7.11.22", "activity": "", "evidence": [ { "id": "G3MX00", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3MX00" } ] } ] }, { "uniprot_ac": "G3N022", "gene_name": "SPEG", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "G3N022", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3N022" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "G3N022", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3N022" } ] } ] }, { "uniprot_ac": "G3N2D2", "gene_name": "TSSK1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "G3N2D2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3N2D2" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "G3N2D2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3N2D2" } ] } ] }, { "uniprot_ac": "G3N2F6", "gene_name": "PIM3", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "G3N2F6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3N2F6" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "G3N2F6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3N2F6" } ] } ] }, { "uniprot_ac": "G3N2J4", "gene_name": "TTBK1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "G3N2J4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3N2J4" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "G3N2J4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3N2J4" } ] } ] }, { "uniprot_ac": "G5E518", "gene_name": "CDK12", "activity": [ { "ec_number": "2.7.11.22", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "G5E518", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G5E518" } ] }, { "ec_number": "2.7.11.23", "activity": "[DNA-directed RNA polymerase] + ATP = phospho-[DNA-directed RNA polymerase] + ADP + H(+).", "evidence": [ { "id": "G5E518", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G5E518" } ] }, { "ec_number": "2.7.11.22", "activity": "", "evidence": [ { "id": "G5E518", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G5E518" } ] }, { "ec_number": "2.7.11.23", "activity": "", "evidence": [ { "id": "G5E518", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G5E518" } ] } ] }, { "uniprot_ac": "G5E577", "gene_name": "MAPK6", "activity": [ { "ec_number": "2.7.11.24", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "G5E577", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G5E577" } ] }, { "ec_number": "2.7.11.24", "activity": "", "evidence": [ { "id": "G5E577", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G5E577" } ] } ] }, { "uniprot_ac": "G5E5A0", "gene_name": "STK17A", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "G5E5A0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G5E5A0" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "G5E5A0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G5E5A0" } ] } ] }, { "uniprot_ac": "G5E5D4", "gene_name": "MARK1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "G5E5D4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G5E5D4" } ] }, { "ec_number": "2.7.11.26", "activity": "L-seryl-[tau protein] + ATP = O-phospho-L-seryl-[tau protein] + ADP + H(+).", "evidence": [ { "id": "G5E5D4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G5E5D4" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "G5E5D4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G5E5D4" } ] }, { "ec_number": "2.7.11.26", "activity": "", "evidence": [ { "id": "G5E5D4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G5E5D4" } ] } ] }, { "uniprot_ac": "G5E5K2", "gene_name": "MASTL", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "G5E5K2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G5E5K2" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "G5E5K2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G5E5K2" } ] } ] }, { "uniprot_ac": "H2XJE8", "gene_name": "AAK1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "H2XJE8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/H2XJE8" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "H2XJE8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/H2XJE8" } ] } ] }, { "uniprot_ac": "H2XJE9", "gene_name": "NLK", "activity": [ { "ec_number": "2.7.11.24", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "H2XJE9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/H2XJE9" } ] }, { "ec_number": "2.7.11.24", "activity": "", "evidence": [ { "id": "H2XJE9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/H2XJE9" } ] } ] }, { "uniprot_ac": "P00516", "gene_name": "PRKG1", "activity": [ { "ec_number": "2.7.11.12", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "P00516", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P00516" } ] }, { "ec_number": "2.7.11.12", "activity": "", "evidence": [ { "id": "P00516", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P00516" } ] } ] }, { "uniprot_ac": "P00517", "gene_name": "PRKACA", "activity": [ { "ec_number": "2.7.11.11", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "P00517", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P00517" } ] }, { "ec_number": "2.7.11.11", "activity": "", "evidence": [ { "id": "P00517", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P00517" } ] } ] }, { "uniprot_ac": "P04409", "gene_name": "PRKCA", "activity": [ { "ec_number": "2.7.11.13", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "P04409", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P04409" } ] }, { "ec_number": "2.7.11.13", "activity": "", "evidence": [ { "id": "P04409", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P04409" } ] } ] }, { "uniprot_ac": "P05126", "gene_name": "PRKCB", "activity": [ { "ec_number": "2.7.11.13", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "P05126", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P05126" } ] }, { "ec_number": "2.7.11.13", "activity": "", "evidence": [ { "id": "P05126", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P05126" } ] } ] }, { "uniprot_ac": "P05128", "gene_name": "PRKCG", "activity": [ { "ec_number": "2.7.11.13", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "P05128", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P05128" } ] }, { "ec_number": "2.7.11.13", "activity": "", "evidence": [ { "id": "P05128", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P05128" } ] } ] }, { "uniprot_ac": "P05131", "gene_name": "PRKACB", "activity": [ { "ec_number": "2.7.11.11", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "P05131", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P05131" } ] }, { "ec_number": "2.7.11.11", "activity": "", "evidence": [ { "id": "P05131", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P05131" } ] } ] }, { "uniprot_ac": "P11023", "gene_name": "RAB3A", "activity": [ { "ec_number": "3.6.5.2", "activity": "GTP + H2O = GDP + phosphate + H(+).", "evidence": [ { "id": "P11023", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P11023" } ] }, { "ec_number": "3.6.5.2", "activity": "", "evidence": [ { "id": "P11023", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P11023" } ] } ] }, { "uniprot_ac": "P20427", "gene_name": "CSNK2A2", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "P20427", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P20427" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "P20427", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P20427" } ] } ] }, { "uniprot_ac": "P32871", "gene_name": "PIK3CA", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "P32871", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P32871" } ] }, { "ec_number": "2.7.1.153", "activity": "a 1,2-diacyl-sn-glycero-3-phospho-(1D-myo-inositol-4,5-bisphosphate) + ATP = a 1,2-diacyl-sn-glycero-3-phospho-(1D-myo-inositol-3,4,5-trisphosphate) + ADP + H(+).", "evidence": [ { "id": "P32871", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P32871" } ] }, { "ec_number": "2.7.1.137", "activity": "a 1,2-diacyl-sn-glycero-3-phospho-(1D-myo-inositol) + ATP = a 1,2-diacyl-sn-glycero-3-phospho-(1D-myo-inositol-3-phosphate) + ADP + H(+).", "evidence": [ { "id": "P32871", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P32871" } ] }, { "ec_number": "2.7.1.153", "activity": "", "evidence": [ { "id": "P32871", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P32871" } ] }, { "ec_number": "2.7.1.137", "activity": "", "evidence": [ { "id": "P32871", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P32871" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "P32871", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P32871" } ] } ] }, { "uniprot_ac": "P35507", "gene_name": "CSNK1B", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "P35507", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P35507" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "P35507", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P35507" } ] } ] }, { "uniprot_ac": "P35508", "gene_name": "CSNK1D", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "P35508", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P35508" } ] }, { "ec_number": "2.7.11.26", "activity": "L-seryl-[tau protein] + ATP = O-phospho-L-seryl-[tau protein] + ADP + H(+).", "evidence": [ { "id": "P35508", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P35508" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "P35508", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P35508" } ] } ] }, { "uniprot_ac": "P35509", "gene_name": "CSNK1G3", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "P35509", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P35509" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "P35509", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P35509" } ] } ] }, { "uniprot_ac": "P46196", "gene_name": "MAPK1", "activity": [ { "ec_number": "2.7.11.24", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "P46196", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P46196" } ] }, { "ec_number": "2.7.11.24", "activity": "", "evidence": [ { "id": "P46196", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P46196" } ] } ] }, { "uniprot_ac": "P48734", "gene_name": "CDK1", "activity": [ { "ec_number": "2.7.11.22", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "P48734", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P48734" } ] }, { "ec_number": "2.7.11.23", "activity": "[DNA-directed RNA polymerase] + ATP = phospho-[DNA-directed RNA polymerase] + ADP + H(+).", "evidence": [ { "id": "P48734", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P48734" } ] }, { "ec_number": "2.7.11.23", "activity": "", "evidence": [ { "id": "P48734", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P48734" } ] }, { "ec_number": "2.7.11.22", "activity": "", "evidence": [ { "id": "P48734", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P48734" } ] } ] }, { "uniprot_ac": "P52175", "gene_name": "NME1", "activity": [ { "ec_number": "3.1.11.-", "activity": "", "evidence": [ { "id": "P52175", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P52175" } ] }, { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "P52175", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P52175" } ] }, { "ec_number": "2.7.4.6", "activity": "UDP + ATP = UTP + ADP.", "evidence": [ { "id": "P52175", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P52175" } ] }, { "ec_number": "2.7.13.3", "activity": "ATP + protein L-histidine = ADP + protein N-phospho-L-histidine.", "evidence": [ { "id": "P52175", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P52175" } ] }, { "ec_number": "2.7.4.18", "activity": "(2E,6E)-farnesyl diphosphate + ATP = (2E,6E)-farnesyl triphosphate + ADP.", "evidence": [ { "id": "P52175", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P52175" } ] }, { "ec_number": "3.1.24.-", "activity": "", "evidence": [ { "id": "P52175", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P52175" } ] }, { "ec_number": "2.7.4.6", "activity": "", "evidence": [ { "id": "P52175", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P52175" } ] } ] }, { "uniprot_ac": "P67827", "gene_name": "CSNK1A1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "P67827", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P67827" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "P67827", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P67827" } ] } ] }, { "uniprot_ac": "P68399", "gene_name": "CSNK2A1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "P68399", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P68399" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "P68399", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P68399" } ] } ] }, { "uniprot_ac": "Q01314", "gene_name": "AKT1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "Q01314", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q01314" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "Q01314", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q01314" } ] } ] }, { "uniprot_ac": "Q02399", "gene_name": "CDK5", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "Q02399", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q02399" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "Q02399", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q02399" } ] } ] }, { "uniprot_ac": "Q08DZ2", "gene_name": "PRP4K", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "Q08DZ2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q08DZ2" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "Q08DZ2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q08DZ2" } ] } ] }, { "uniprot_ac": "Q08E52", "gene_name": "PAK1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "Q08E52", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q08E52" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "Q08E52", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q08E52" } ] } ] }, { "uniprot_ac": "Q0V7M1", "gene_name": "PSKH1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "Q0V7M1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q0V7M1" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "Q0V7M1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q0V7M1" } ] } ] }, { "uniprot_ac": "Q0VD22", "gene_name": "STK33", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "Q0VD22", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q0VD22" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "Q0VD22", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q0VD22" } ] } ] }, { "uniprot_ac": "Q17QV9", "gene_name": "STK40", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "Q17QV9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q17QV9" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "Q17QV9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q17QV9" } ] } ] }, { "uniprot_ac": "Q17R13", "gene_name": "TNK2", "activity": [ { "ec_number": "2.7.10.2", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "Q17R13", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q17R13" } ] }, { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "Q17R13", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q17R13" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "Q17R13", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q17R13" } ] }, { "ec_number": "2.7.10.2", "activity": "", "evidence": [ { "id": "Q17R13", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q17R13" } ] } ] }, { "uniprot_ac": "Q1RMT7", "gene_name": "RIOK3", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "Q1RMT7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q1RMT7" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "Q1RMT7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q1RMT7" } ] } ] }, { "uniprot_ac": "Q1RMT8", "gene_name": "IRAK4", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "Q1RMT8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q1RMT8" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "Q1RMT8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q1RMT8" } ] } ] }, { "uniprot_ac": "Q28021", "gene_name": "ROCK2", "activity": [ { "ec_number": "2.7.11.39", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "Q28021", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q28021" } ] }, { "ec_number": "2.7.11.39", "activity": "", "evidence": [ { "id": "Q28021", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q28021" } ] } ] }, { "uniprot_ac": "Q2HJF7", "gene_name": "CAMK2D", "activity": [ { "ec_number": "2.7.11.17", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "Q2HJF7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q2HJF7" } ] }, { "ec_number": "2.7.11.17", "activity": "", "evidence": [ { "id": "Q2HJF7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q2HJF7" } ] } ] }, { "uniprot_ac": "Q2KIP2", "gene_name": "HASPIN", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "Q2KIP2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q2KIP2" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "Q2KIP2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q2KIP2" } ] } ] }, { "uniprot_ac": "Q2KJG8", "gene_name": "BCKDK", "activity": [ { "ec_number": "2.7.11.-", "activity": "", "evidence": [ { "id": "Q2KJG8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q2KJG8" } ] }, { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "Q2KJG8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q2KJG8" } ] }, { "ec_number": "2.7.11.4", "activity": "L-seryl-[3-methyl-2-oxobutanoate dehydrogenase] + ATP = O-phospho-L-seryl-[3-methyl-2-oxobutanoate dehydrogenase] + ADP + H(+).", "evidence": [ { "id": "Q2KJG8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q2KJG8" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "Q2KJG8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q2KJG8" } ] } ] }, { "uniprot_ac": "Q2LGB3", "gene_name": "IRAK1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "Q2LGB3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q2LGB3" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "Q2LGB3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q2LGB3" } ] } ] }, { "uniprot_ac": "Q2TA06", "gene_name": "AURKA", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "Q2TA06", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q2TA06" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "Q2TA06", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q2TA06" } ] } ] }, { "uniprot_ac": "Q2TA25", "gene_name": "PLK1", "activity": [ { "ec_number": "2.7.11.21", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "Q2TA25", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q2TA25" } ] }, { "ec_number": "2.7.11.21", "activity": "", "evidence": [ { "id": "Q2TA25", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q2TA25" } ] } ] }, { "uniprot_ac": "Q2TBL8", "gene_name": "CDK10", "activity": [ { "ec_number": "2.7.11.22", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "Q2TBL8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q2TBL8" } ] }, { "ec_number": "2.7.11.22", "activity": "", "evidence": [ { "id": "Q2TBL8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q2TBL8" } ] } ] }, { "uniprot_ac": "Q2YDN8", "gene_name": "VRK3", "activity": [ { "ec_number": "2.7.11.22", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "Q2YDN8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q2YDN8" } ] }, { "ec_number": "2.7.11.22", "activity": "", "evidence": [ { "id": "Q2YDN8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q2YDN8" } ] } ] }, { "uniprot_ac": "Q32KY4", "gene_name": "CDK4", "activity": [ { "ec_number": "2.7.11.22", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "Q32KY4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q32KY4" } ] }, { "ec_number": "2.7.11.22", "activity": "", "evidence": [ { "id": "Q32KY4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q32KY4" } ] } ] }, { "uniprot_ac": "Q32L23", "gene_name": "LIMK2", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "Q32L23", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q32L23" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "Q32L23", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q32L23" } ] } ] }, { "uniprot_ac": "Q32PI1", "gene_name": "VRK1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "Q32PI1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q32PI1" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "Q32PI1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q32PI1" } ] } ] }, { "uniprot_ac": "Q3MHJ9", "gene_name": "CAMK2B", "activity": [ { "ec_number": "2.7.11.17", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "Q3MHJ9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q3MHJ9" } ] }, { "ec_number": "2.7.11.17", "activity": "", "evidence": [ { "id": "Q3MHJ9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q3MHJ9" } ] } ] }, { "uniprot_ac": "Q3SWY6", "gene_name": "STK25", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "Q3SWY6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q3SWY6" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "Q3SWY6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q3SWY6" } ] } ] }, { "uniprot_ac": "Q3SX21", "gene_name": "CLK3", "activity": [ { "ec_number": "2.7.12.1", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "Q3SX21", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q3SX21" } ] }, { "ec_number": "2.7.12.1", "activity": "", "evidence": [ { "id": "Q3SX21", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q3SX21" } ] } ] }, { "uniprot_ac": "Q3SYZ2", "gene_name": "MAPKAPK3", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "Q3SYZ2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q3SYZ2" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "Q3SYZ2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q3SYZ2" } ] } ] }, { "uniprot_ac": "Q3SZJ2", "gene_name": "RIPK2", "activity": [ { "ec_number": "2.7.10.2", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "Q3SZJ2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q3SZJ2" } ] }, { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "Q3SZJ2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q3SZJ2" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "Q3SZJ2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q3SZJ2" } ] } ] }, { "uniprot_ac": "Q3SZW1", "gene_name": "TSSK1B", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "Q3SZW1", 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"name": "GON4L", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TS91", "locus": { "chromosome": "3", "start_pos": 15038563, "end_pos": 14898294, "strand": "-", "evidence": [ { "database": "Ensembl Gene", "id": "ENSBTAG00000020356", "url": "https://www.ensembl.org/id/ENSBTAG00000020356" } ] } } ], "crossref": [ { "id": "ENSBTAG00000020356", "url": "https://bgee.org/?page=gene&gene_id=ENSBTAG00000020356", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "cd12202", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd12202", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "526125", "url": "https://www.ncbi.nlm.nih.gov/gene/526125", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR001005", "url": "https://www.ebi.ac.uk/interpro/entry/IPR001005", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR003822", "url": "https://www.ebi.ac.uk/interpro/entry/IPR003822", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR009057", "url": "https://www.ebi.ac.uk/interpro/entry/IPR009057", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR036600", "url": "https://www.ebi.ac.uk/interpro/entry/IPR036600", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR049257", "url": "https://www.ebi.ac.uk/interpro/entry/IPR049257", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR052435", "url": "https://www.ebi.ac.uk/interpro/entry/IPR052435", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "bta:526125", "url": "https://www.genome.jp/dbget-bin/www_bget?bta:526125", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "HRNYKDC", "url": "https://omabrowser.org/oma/group/HRNYKDC/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "A0A3Q1MC82", "url": "https://www.orthodb.org/?gene=A0A3Q1MC82", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "F1MP31", "url": "https://www.orthodb.org/?gene=F1MP31", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR16088", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR16088", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR16088:SF3", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR16088:SF3", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF02671", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF02671", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF21227", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF21227", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "A0A3Q1LPU2", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1LPU2", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A3Q1LPU2-1", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1LPU2-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A3Q1MC82", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1MC82", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A3Q1MC82-1", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1MC82-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0AAA9TS91", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TS91", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0AAA9TS91-1", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TS91-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "F1MP31", "url": "https://www.uniprot.org/uniprotkb/F1MP31", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "F1MP31-1", "url": "https://www.uniprot.org/uniprotkb/F1MP31-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MLPCKKRRTTLTESPQHQGNQEEDDLDLQAAGKPESDLGSVKDLGSVSLSWSPSHGRAADLEVQAAGIQLGMEDPSLSSRMLTEDTNVAVLEAVDVAISQEITLASLESSQPVNTHIGKGKLQATSSRRGKKITLRPGSVTQEDRGDHPIAKEPFSEEPSEEVKAEGGKSQMHSGGEMPSLPSDSHSAKPAAPPRKSSQPDVCASPQEKPLRTLAHQAEEETEDGGLFIPMEEHDGEENEKRRKKKKGTKRKRDGRDQEERTLSCDLKLDDMLDRTLEDGAKQHNLTAVNVRNILHEVITNEHVVAMMKAAISETEDMPMFEPKMTRSKLKEVVEKGVVIPTWNISPIKKANEIKPPQFVDIHLEDDDSSDEEYQPDDEEEDETAEESLLESDVESTASSPRGAKKSRLRQSSEMTETDEESGILSEAEKVTTPAIRHISAEVVPMGPPPPPKPKQTRDSTFMEKLHAVDEELASSPVCMDSFQPMDDSLIAFRTRSKMPLKDVPLGQLEAELRAPDITPDMYDPNTADDEDWKMWLGGLMNDDVGNEDEADDDDDPEYNFLEDLDEPDTEDFRTDRAVRITKKEVNELMEELFETFQDEMGFSNMEDDGPEEEERVAEPRPNFNTPQALRFEEPLANLLNEQHRTVKELLEQLKMKKSSAKQQQEVERVKPQREKVHQTLILDPAQRKRLQQQMQQHVQLLTQIHLLASSNPSLSSEASTTRIFLKELGTFAQSSIALHHQFNSKFQTLFQPCNLMGAMKLIEDFSTHVSVDWSPRKTVKKTACKLPCLPKQVAWILATSKVFMYPELLPVCSLKAKNPQDKIFFTKAEDNLLALGLKHFEGTEFPKPLISKYLLTCKTAHQLTVRIKNLNMNRAPDNIIKFYKKTKQLPILMKCCEEIQPHQWKPPVEREEHRLPFWLKASLPSIQEELRRIADGAREVGNVTGTTEINSDPGLGKGSSELESETRYPLLLPKGVVLKLKPVANRFSRKAWRQKRSSTLKPFFFGPSPSLQPSSSSGKTPARSAHSEAPPSKMVVRIPPLIQPATVLQAVPGGPPLGVPGGDSFESPAALPATAAEARTSFPLPEPQTLLSSAPVPKLMLPSLAPSKFRKPCVKRRASKRKGPKASLCLKPAPLIHPAPVFFTVPATTVKVVSLGSGCNVMQPVSAAVAQSPQTIPITTLLVNPTPFPCSLNQPLVASSIPPLIVSGTSVNLSVPSTPEDKAPVNVDVGCPLAEGKNAFQGLEPKLEPRELSPLCAAVFPKEEHSPGPPAADRVCQEQLSESSAYGWTIVKTEEGRQAPEPLPQGFRESLNPPEDLEEMVKMEPKDPGEDTCGGSLEQGSHEEIKEEHSVESDTSFPSEESSRPREGKKQTGLQQEEQRSQAAQTLSASQEPPGEGNSGDVSKGSPRDASFSTDPEMVLSSPLGKPEDLSSVDGQSVGTPAGPETAGEKDGPEEEEEEDFDDLTQDEEDEMSSASEESVLSVPELQETMEKLTWLASERRMSQEGESEEENSQEENSEPEEEEEEEAEGMENLQKEDEMMDEAIGDPAEKPPATFDSPKAAPEVETSRTPPGESIKAAGKGRSNHRARSKRGSRARASKDTSKLLLLYDEDILERDPLREQKDLAFAQAYLTRVREALQHIPGKYEDFLQVIYEFESSTQRQTAVDLYKSLQILLQDWPQLLKDFAAFLLPEQALACGLFEEQQAFEKSRKFLRQLEICFAENPSHHQKIIKVLQSCADCLPQEITELKTQMWQLLKGHDHLQDEFSIFFDHLRPAASRMGDFEEINWTEEKEYEFDGFEEVALPDVEEEEEPPKIPTTSKNKRRKEIGVQNHDKEAEWPDAAKDCACSCHEGGPDSKMKKSKRRSCSHCSSKVCDSKSYKSKEPHELVGSSPHREASLMPGAKEAGQGKDVMEEEAPEERESVEAAQSRTGRSTRKGEMPAAAGLAAGSTLPSPQEVTFTDQLLLDGPPPPCSPETPQLPSTAGTVLCAVRSNQAGPAVLSGPRASPRPQHEGEDHKPGAELEPSMPWDASETEKLPGTVEPPASFLSPVSSRTGDFGRRQVPGRADTQESWLPSGRAGVSTADGMSPLRGVSSAGVDTAETSKAPRGGLAKDSGAQGKGPAGELQAKATEATVCANNSKVSSTGEKVVLWTREADRVILTMCQEQGAQPQTFSVISQQLGNKTPTEVSHRFRELVQLFHTACEASSEDEDDATSTSNTDQLSDHGDLLSEEELDE", "length": 2239, "header": "tr|A0AAA9TS91-1|A0AAA9TS91_BOVIN Isoform 1 of GON-4-like protein OS=Bos taurus OX=9913 GN=GON4L PE=4 SV=1 CANONICAL=A0AAA9TS91-1" }, "isoforms": [ { "isoform_ac": "A0A3Q1LPU2-1", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1LPU2/entry", "sequence": { "sequence": "MLPCKKRRTTLTESPQHQGNQEEDDLDLQAAGKPESDLGSVKDLGSVSLSWSPSHGRAADLEVQAAGIQLGMEDPSLSSRMLTEDTNVAVLEAVDVAISQEITLASLESSQPVNTHIGKGKLQATSSRRGKKITLRPGSVTQEDRGDHPIAKEPFSEEPSEEVKAEGGKSQMHSGGEMPSLPSDSHSAKPAAPPRKSSQPDVCASPQEKPLRTLAHQAEEETEDGGLFIPMEEHDGEENEKRRKKKKGTKRKRDGRDQEERTLSCDLKLDDMLDRTLEDGAKQHNLTAVNVRNILHEVITNEHVVAMMKAAISETEDMPMFEPKMTRSKLKEVVEKGVVIPTWNISPIKKANEIKPPQFVDIHLEDDDSSDEEYQPDDEEEDETAEESLLESDVESTASSPRGAKKSRLRQSSEMTETDEESGILSEAEKVTTPAIRHISAEVVPMGPPPPPKPKQTRDSTFMEKLHAVDEELASSPVCMDSFQPMDDSLIAFRTRSKMPLKDVPLGQLEAELRAPDITPDMYDPNTADDEDWKMWLGGLMNDDVGNEDEADDDDDPEYNFLEDLDEPDTEDFRTDRAVRITKKEVNELMEELFETFQDEMGFSNMEDDGPEEEERVAEPRPNFNTPQALRFEEPLANLLNEQHRTVKELLEQLKMKKSSAKQQQEVERVKPQREKVHQTLILDPAQRKRLQQQMQQHVQLLTQIHLLASSNPSLSSEASTTRIFLKELGTFAQSSIALHHQFNSKFQTLFQPCNLMGAMKLIEDFSTHVSVDWSPRKTVKKTACKLPCLPKQVAWILATSKVFMYPELLPVCSLKAKNPQDKIFFTKAEDNLLALGLKHFEGTEFPKPLISKYLLTCKTAHQLTVRIKNLNMNRAPDNIIKFYKKTKQLPILMKCCEEIQPHQWKPPVEREEHRLPFWLKASLPSIQEELRRIADGAREVGNVTGTTEINSDPGLGKGSSELESETRYPLLLPKGVVLKLKPVANRFSRKAWRQKRSSTLKPFFFGPSPSLQPSSSSGKTPARSAHSEAPPSKMVVRIPPLIQPATVLQAVPGGPPLGVPGGDSFESPAALPATAAEARTSFPLPEPQTLLSSAPVPKLMLPSLAPSKFRKPCVKRRASKRKGPKASLCLKPAPLIHPAPVFFTVPATTVKVVSLGSGCNVMQPVSAAVAQSPQTIPITTLLVNPTPFPCSLNQPLVASSIPPLIVSGTSVNLSVPSTPEDKAPVNVDVGCPLAEGKNAFQGLEPKLEPRELSPLCAAVFPKEEHSPGPPAADRVCQEQLSESSAYGWTIVKTEEGRQAPEPLPQGFRESLNTCPEDLEEMVKMEPKDPGEDTCGGSLEQGSHEEIKEEHSVESDTSFPSEESSRPREGKKQTGLQQEEQRSQAAQTLSASQEPPGEGNSGDVSKGSPRDASFSTDPEMVLSSPLGKPEDLSSVDGQSVGTPAGPETAGEKDGPEEEEEEDFDDLTQDEEDEMSSASEESVLSVPELQETMEKLTWLASERRMSQEGESEEENSQEENSEPEEEEEEEAEGMENLQKEDEMMDEAIGDPAEKPPATFDSPKAAPEVETSRTPPGESIKAAGKGRSNHRARSKRGSRARASKDTSKLLLLYDEDILERDPLREQKDLAFAQAYLTRVREALQHIPGKYEDFLQVIYEFESSTQRQTAVDLYKSLQILLQDWPQLLKDFAAFLLPEQALACGLFEEQQAFEKSRKFLRQLEICFAENPSHHQKIIKVLQSCADCLPQEITELKTQMWQLLKGHDHLQDEFSIFFDHLRPAASRMGDFEEINWTEEKEYEFDGFEEVALPDVEEEEEPPKIPTTSKNKRRKEIGVQNHDKEAEWPDAAKDCACSCHEGGPDSKMKKSKRRSCSHCSSKVCDSKSYKSKEPHELVGSSPHREASLMPGAKEAGQGKDVMEEEAPEERESVEAAQSRTGRSTRKGEMPAAGLAAGSTLPSPQEVTFTDQLLLDGPPPPCSPETPQLPSTAGTVLCAVRSNQAGPAVLSGPRASPRPQHEGEDHKPGAELEPSMPWDASETEKLPGTVEPPASFLSPVSSRTGDFGRRQVPGRADTQESWLPSGRAGVSTADGMSPLRGVSSAGVDTAETSKAPRGGLAKDSGAQGKGPAGELQAKATEATVCANNSKVSSTGEKVVLWTREADRVILTMCQEQGAQPQTFSVISQQLGNKTPTEVSRVGLARATSPRGTKEGFGKRAAWPTKMIGDCKVLP", "length": 2227, "header": "tr|A0A3Q1LPU2-1|A0AAA9TS91_BOVIN Computationally mapped isoform of GON-4-like protein OS=Bos taurus OX=9913 GN=GON4L PE=4 SV=1 CANONICAL=A0AAA9TS91-1" }, "locus": { "chromosome": "3", "start_pos": 15037559, "end_pos": 14954772, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000083667.3", "url": "https://www.ensembl.org/id/ENSBTAT00000083667.3" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000058966.2", "url": "https://www.ensembl.org/id/ENSBTAP00000058966.2" } ] } }, { "isoform_ac": "A0A3Q1MC82-1", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1MC82/entry", "sequence": { "sequence": "MLAVRIEKKGKSQMHSGGEMPSLPSDSHSAKPAAPPRKSSQPDVCASPQEKPLRTLAHQAEEETEDGGLFIPMEEHDGEENEKRRKKKKGTKRKRDGRDQEERTLSCDLKLDDMLDRTLEDGAKQHNLTAVNVRNILHEVITNEHVVAMMKAAISETEDMPMFEPKMTRSKLKEVVEKGVVIPTWNISPIKKANEIKPPQFVDIHLEDDDSSDEEYQPDDEEEDETAEESLLESDVESTASSPRGAKKSRLRQSSEMTETDEESGILSEAEKVTTPAIRHISAEVVPMGPPPPPKPKQTRDSTFMEKLHAVDEELASSPVCMDSFQPMDDSLIAFRTRSKMPLKDVPLGQLEAELRAPDITPDMYDPNTADDEDWKMWLGGLMNDDVGNEDEADDDDDPEYNFLEDLDEPDTEDFRTDRAVRITKKEVNELMEELFETFQDEMGFSNMEDDGPEEEERVAEPRPNFNTPQALRFEEPLANLLNEQHRTVKELLEQLKMKKSSAKQQQEVERVKPQREKVHQTLILDPAQRKRLQQQMQQHVQLLTQIHLLASSNPSLSSEASTTRIFLKELGTFAQSSIALHHQFNSKFQTLFQPCNLMGAMKLIEDFSTHVSVDWSPRKTVKKTACKLPCLPKQVAWILATSKVFMYPELLPVCSLKAKNPQDKIFFTKAEDNLLALGLKHFEGTEFPKPLISKYLLTCKTAHQLTVRIKNLNMNRAPDNIIKFYKKTKQLPILMKCCEEIQPHQWKPPVEREEHRLPFWLKASLPSIQEELRRIADGAREVGNVTGTTEINSDPGLGKGSSELESETRYPLLLPKGVVLKLKPVANRFSRKAWRQKRSSTLKPFFFGPSPSLQPSSSSGKTPARSAHSEAPPSKMVVRIPPLIQPATVLQAVPGGPPLGVPGGDSFESPAALPATAAEARTSFPLPEPQTLLSSAPVPKLMLPSLAPSKFRKPCVKRRASKRKGPKASLCLKPAPLIHPAPVFFTVPATTVKVVSLGSGCNVMQPVSAAVAQSPQTIPITTLLVNPTPFPCSLNQPLVASSIPPLIVSGTSVNLSVPSTPEDKAPVNVDVGCPLAEGKNAFQGLEPKLEPRELSPLCAAVFPKEEHSPGPPAADRVCQEQLSESSAYGWTIVKTEEGRQAPEPLPQGFRESLNTCPEDLEEMVKMEPKDPGEDTCGGSLEQGSHEEIKEEHSVESDTSFPSEESSRPREGKKQTGLQQEEQRSQAAQTLSASQEPPGEGNSGDVSKGSPRDASFSTDPEMVLSSPLGKPEDLSSVDGQSVGTPAGPETAGEKDGPEEEEEEDFDDLTQDEEDEMSSASEESVLSVPELQETMEKLTWLASERRMSQEGESEEENSQEENSEPEEEEEEEAEGMENLQKEDEMMDEAIGDPAEKPPATFDSPKAAPEVETSRTPPGESIKAAGKGRSNHRARSKRGSRARASKDTSKLLLLYDEDILERDPLREQKDLAFAQAYLTRVREALQHIPGKYEDFLQVIYEFESSTQRQTAVDLYKSLQILLQDWPQLLKDFAAFLLPEQALACGLFEEQQAFEKSRKFLRQLEICFAENPSHHQKIIKVLQSCADCLPQEITELKTQMWQLLKGHDHLQDEFSIFFDHLRPAASRMGDFEEINWTEEKEYEFDGFEEVALPDVEEEEEPPKIPTTSKNKRRKEIGVQNHDKEAEWPDAAKDCACSCHEGGPDSKMKKSKRRSCSHCSSKVCDSKSYKSKEPHELVGSSPHREASLMPGAKEAGQGKDVMEEEAPEERESVEAAQSRTGRSTRKGEMPAAGLAAGSTLPSPQEVTFTDQLLLDGPPPPCSPETPQLPSTAGTVLCAVRSNQAGPAVLSGPRASPRPQHEGEDHKPGAELEPSMPWDASETEKLPGTVEPPASFLSPVSSRTGDFGRRQVPGRADTQESWLPSGRAGVSTADGMSPLRGVSSAGVDTAETSKAPRGGLAKDSGAQGKGPAGELQAKATEATVCANNSKVSSTGEKVVLWTREADRVILTMCQEQGAQPQTFSVISQQLGNKTPTEVSHRFRELVQLFHTACEASSEDEDDATSTSNTDQLSDHGDLLSEEELDE", "length": 2081, "header": "tr|A0A3Q1MC82-1|A0AAA9TS91_BOVIN Computationally mapped isoform of GON-4-like protein OS=Bos taurus OX=9913 GN=GON4L PE=4 SV=2 CANONICAL=A0AAA9TS91-1" }, "locus": { "chromosome": "3", "start_pos": 15038175, "end_pos": 14956482, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000070834.2", "url": "https://www.ensembl.org/id/ENSBTAT00000070834.2" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000068420.2", "url": "https://www.ensembl.org/id/ENSBTAP00000068420.2" } ] } }, { "isoform_ac": "A0AAA9TS91-1", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TS91/entry", "sequence": { "sequence": "MLPCKKRRTTLTESPQHQGNQEEDDLDLQAAGKPESDLGSVKDLGSVSLSWSPSHGRAADLEVQAAGIQLGMEDPSLSSRMLTEDTNVAVLEAVDVAISQEITLASLESSQPVNTHIGKGKLQATSSRRGKKITLRPGSVTQEDRGDHPIAKEPFSEEPSEEVKAEGGKSQMHSGGEMPSLPSDSHSAKPAAPPRKSSQPDVCASPQEKPLRTLAHQAEEETEDGGLFIPMEEHDGEENEKRRKKKKGTKRKRDGRDQEERTLSCDLKLDDMLDRTLEDGAKQHNLTAVNVRNILHEVITNEHVVAMMKAAISETEDMPMFEPKMTRSKLKEVVEKGVVIPTWNISPIKKANEIKPPQFVDIHLEDDDSSDEEYQPDDEEEDETAEESLLESDVESTASSPRGAKKSRLRQSSEMTETDEESGILSEAEKVTTPAIRHISAEVVPMGPPPPPKPKQTRDSTFMEKLHAVDEELASSPVCMDSFQPMDDSLIAFRTRSKMPLKDVPLGQLEAELRAPDITPDMYDPNTADDEDWKMWLGGLMNDDVGNEDEADDDDDPEYNFLEDLDEPDTEDFRTDRAVRITKKEVNELMEELFETFQDEMGFSNMEDDGPEEEERVAEPRPNFNTPQALRFEEPLANLLNEQHRTVKELLEQLKMKKSSAKQQQEVERVKPQREKVHQTLILDPAQRKRLQQQMQQHVQLLTQIHLLASSNPSLSSEASTTRIFLKELGTFAQSSIALHHQFNSKFQTLFQPCNLMGAMKLIEDFSTHVSVDWSPRKTVKKTACKLPCLPKQVAWILATSKVFMYPELLPVCSLKAKNPQDKIFFTKAEDNLLALGLKHFEGTEFPKPLISKYLLTCKTAHQLTVRIKNLNMNRAPDNIIKFYKKTKQLPILMKCCEEIQPHQWKPPVEREEHRLPFWLKASLPSIQEELRRIADGAREVGNVTGTTEINSDPGLGKGSSELESETRYPLLLPKGVVLKLKPVANRFSRKAWRQKRSSTLKPFFFGPSPSLQPSSSSGKTPARSAHSEAPPSKMVVRIPPLIQPATVLQAVPGGPPLGVPGGDSFESPAALPATAAEARTSFPLPEPQTLLSSAPVPKLMLPSLAPSKFRKPCVKRRASKRKGPKASLCLKPAPLIHPAPVFFTVPATTVKVVSLGSGCNVMQPVSAAVAQSPQTIPITTLLVNPTPFPCSLNQPLVASSIPPLIVSGTSVNLSVPSTPEDKAPVNVDVGCPLAEGKNAFQGLEPKLEPRELSPLCAAVFPKEEHSPGPPAADRVCQEQLSESSAYGWTIVKTEEGRQAPEPLPQGFRESLNPPEDLEEMVKMEPKDPGEDTCGGSLEQGSHEEIKEEHSVESDTSFPSEESSRPREGKKQTGLQQEEQRSQAAQTLSASQEPPGEGNSGDVSKGSPRDASFSTDPEMVLSSPLGKPEDLSSVDGQSVGTPAGPETAGEKDGPEEEEEEDFDDLTQDEEDEMSSASEESVLSVPELQETMEKLTWLASERRMSQEGESEEENSQEENSEPEEEEEEEAEGMENLQKEDEMMDEAIGDPAEKPPATFDSPKAAPEVETSRTPPGESIKAAGKGRSNHRARSKRGSRARASKDTSKLLLLYDEDILERDPLREQKDLAFAQAYLTRVREALQHIPGKYEDFLQVIYEFESSTQRQTAVDLYKSLQILLQDWPQLLKDFAAFLLPEQALACGLFEEQQAFEKSRKFLRQLEICFAENPSHHQKIIKVLQSCADCLPQEITELKTQMWQLLKGHDHLQDEFSIFFDHLRPAASRMGDFEEINWTEEKEYEFDGFEEVALPDVEEEEEPPKIPTTSKNKRRKEIGVQNHDKEAEWPDAAKDCACSCHEGGPDSKMKKSKRRSCSHCSSKVCDSKSYKSKEPHELVGSSPHREASLMPGAKEAGQGKDVMEEEAPEERESVEAAQSRTGRSTRKGEMPAAAGLAAGSTLPSPQEVTFTDQLLLDGPPPPCSPETPQLPSTAGTVLCAVRSNQAGPAVLSGPRASPRPQHEGEDHKPGAELEPSMPWDASETEKLPGTVEPPASFLSPVSSRTGDFGRRQVPGRADTQESWLPSGRAGVSTADGMSPLRGVSSAGVDTAETSKAPRGGLAKDSGAQGKGPAGELQAKATEATVCANNSKVSSTGEKVVLWTREADRVILTMCQEQGAQPQTFSVISQQLGNKTPTEVSHRFRELVQLFHTACEASSEDEDDATSTSNTDQLSDHGDLLSEEELDE", "length": 2239, "header": "tr|A0AAA9TS91-1|A0AAA9TS91_BOVIN Isoform 1 of GON-4-like protein OS=Bos taurus OX=9913 GN=GON4L PE=4 SV=1 CANONICAL=A0AAA9TS91-1" }, "locus": { "chromosome": "3", "start_pos": 15038175, "end_pos": 14898294, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000088680.1", "url": "https://www.ensembl.org/id/ENSBTAT00000088680.1" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000101467.1", "url": "https://www.ensembl.org/id/ENSBTAP00000101467.1" } ] } }, { "isoform_ac": "F1MP31-1", "url": "https://www.uniprot.org/uniprotkb/F1MP31/entry", "sequence": { "sequence": "MLPCKKRRTTLTESPQHQGNQEEDDLDLQAAGKPESDLGSVKDLGSVSLSWSPSHGRAADLEVQAAGIQLGMEDPSLSSRMLTEDTNVAVLEAVDVAISQEITLASLESSQPVNTHIGKGKLQATSSRRGKKITLRPGSVTQEDRGDHPIAKEPFSEEPSEEVKAEGGKSQMHSGGEMPSLPSDSHSAKPAAPPRKSSQPDVCASPQEKPLRTLAHQAEEETEDGGLFIPMEEHDGEENEKRRKKKKGTKRKRDGRDQEERTLSCDLKLDDMLDRTLEDGAKQHNLTAVNVRNILHEVITNEHVVAMMKAAISETEDMPMFEPKMTRSKLKEVVEKGVVIPTWNISPIKKANEIKPPQFVDIHLEDDDSSDEEYQPDDEEEDETAEESLLESDVESTASSPRGAKKSRLRQSSEMTETDEESGILSEAEKVTTPAIRHISAEVVPMGPPPPPKPKQTRDSTFMEKLHAVDEELASSPVCMDSFQPMDDSLIAFRTRSKMPLKDVPLGQLEAELRAPDITPDMYDPNTADDEDWKMWLGGLMNDDVGNEDEADDDDDPEYNFLEDLDEPDTEDFRTDRAVRITKKEVNELMEELFETFQDEMGFSNMEDDGPEEEERVAEPRPNFNTPQALRFEEPLANLLNEQHRTVKELLEQLKMKKSSAKQQQEVERVKPQREKVHQTLILDPAQRKRLQQQMQQHVQLLTQIHLLASSNPSLSSEASTTRIFLKELGTFAQSSIALHHQFNSKFQTLFQPCNLMGAMKLIEDFSTHVSVDWSPRKTVKKTACKLPCLPKQVAWILATSKVFMYPELLPVCSLKAKNPQDKIFFTKAEDNLLALGLKHFEGTEFPKPLISKYLLTCKTAHQLTVRIKNLNMNRAPDNIIKFYKKTKQLPILMKCCEEIQPHQWKPPVEREEHRLPFWLKASLPSIQEELRRIADGAREVGNVTGTTEINSDPGLGKGSSELESETRYPLLLPKGVVLKLKPVANRFSRKAWRQKRSSTLKPFFFGPSPSLQPSSSSGKTPARSAHSEAPPSKMVVRIPPLIQPATVLQAVPGGPPLGVPGGDSFESPAALPATAAEARTSFPLPEPQTLLSSAPVPKLMLPSLAPSKFRKPCVKRRASKRKGPKASLCLKPAPLIHPAPVFFTVPATTVKVVSLGSGCNVMQPVSAAVAQSPQTIPITTLLVNPTPFPCSLNQPLVASSIPPLIVSGTSVNLSVPSTPEDKAPVNVDVGCPLAEGKNAFQGLEPKLEPRELSPLCAAVFPKEEHSPGPPAADRVCQEQLSESSAYGWTIVKTEEGRQAPEPLPQGFRESLNTCPEDLEEMVKMEPKDPGEDTCGGSLEQGSHEEIKEEHSVESDTSFPSEESSRPREGKKQTGLQQEEQRSQAAQTLSASQEPPGEGNSGDVSKGSPRDASFSTDPEMVLSSPLGKPEDLSSVDGQSVGTPAGPETAGEKDGPEEEEEEDFDDLTQDEEDEMSSASEESVLSVPELQETMEKLTWLASERRMSQEGESEEENSQEENSEPEEEEEEEAEGMENLQKEDEMMDEAIGDPAEKPPATFDSPKAAPEVETSRTPPGESIKAAGKGRSNHRARSKRGSRARASKDTSKLLLLYDEDILERDPLREQKDLAFAQAYLTRVREALQHIPGKYEDFLQVIYEFESSTQRQTAVDLYKSLQILLQDWPQLLKDFAAFLLPEQALACGLFEEQQAFEKSRKFLRQLEICFAENPSHHQKIIKVLQSCADCLPQEITELKTQMWQLLKGHDHLQDEFSIFFDHLRPAASRMGDFEEINWTEEKEYEFDGFEEVALPDVEEEEEPPKIPTTSKNKRRKEIGVQNHDKEAEWPDAAKDCACSCHEGGPDSKMKKSKRRSCSHCSSKVCDSKSYKSKEPHELVGSSPHREASLMPGAKEAGQGKDVMEEEAPEERESVEAAQSRTGRSTRKGEMPAAGLAAGSTLPSPQEVTFTDQLLLDGPPPPCSPETPQLPSTAGTVLCAVRSNQAGPAVLSGPRASPRPQHEGEDHKPGAELEPSMPWDASETEKLPGTVEPPASFLSPVSSRTGDFGRRQVPGRADTQESWLPSGRAGVSTADGMSPLRGVSSAGVDTAETSKAPRGGLAKDSGAQGKGPAGELQAKATEATVCANNSKVSSTGEKVVLWTREADRVILTMCQEQGAQPQTFSVISQQLGNKTPTEVSHRFRELVQLFHTACEASSEDEDDATSTSNTDQLSDHGDLLSEEELDE", "length": 2239, "header": "tr|F1MP31-1|A0AAA9TS91_BOVIN Computationally mapped isoform of GON-4-like protein OS=Bos taurus OX=9913 GN=GON4L PE=4 SV=1 CANONICAL=A0AAA9TS91-1" }, "locus": { "chromosome": "3", "start_pos": 15038175, "end_pos": 14954772, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000027126.8", "url": "https://www.ensembl.org/id/ENSBTAT00000027126.8" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000027126.5", "url": "https://www.ensembl.org/id/ENSBTAP00000027126.5" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [ { "id": "bta:526125", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?bta:526125", "resource": "KEGG Pathway" } ], "orthologs": [ { "uniprot_canonical_ac": "A0A8V1ADR8-1", "protein_name": "GON-4-like protein", "gene_name": "GON4L", "tax_id": 9031, "organism": "Gallus gallus", "sequence": { "sequence": "MALSLKMLPCKKRRAAAAGPHSPRERSGSGEDGEPPPPQPPPPPPAAASSAVAAAVWRTPAEALPRGGRRPPQEGNEGRPGAAEPCAAPPERGEDAKRLEGGKEGKTPKLHTEVEANVQRDLCLTDNPSAVQESPSRSNLQLAVRSPAAVKLLKSTRPEEQDGEDIERRKRRRKANKRKREGKSQEEERTLSCDIKLDDTLDRTLEDGAKQHNLTVVNVRNILHEVITNEHVVAMMKAAISETEDIPLFEPKMTRSKLKEVVEKGVVIPTWNISPIKKANEVKPPQFVDIPLEEDDSSDEEYQPDDEDEDETAEESLLESDVESTASSPRGAKRSRTRRSSDEEGGALCEVEKVPTPVVRHISAEVVPMGPPPPPKPKQSKDSTFMEKLHAVDEELASSPVCMDSYQPLEDSLIAFRTRSKRPLKDVPLGQLEAELRAPDITPDMYDPNTADDEEWKRWLGGLMNDDVENEDELDDDDDPEYNFLEDLDEPDTEDFRNDRAVRITKKEVNELMEELFETFQDEMGFSNMEDEGPEDEDNVTESRPNFNTPQALRFEEPLANLLNEQHRTVKEQLEQLRMKKSSIKPPQEAEKAKPQNEKPLQSLVLDCAQRKRLQQQMQQHVQLLTQIHLLASSNPALSSEASTTKMFLSELGNFARSSTLLRQSFYPKFQTMFQPCNLKGALQLVEDFHAQVQVDCSPRKAVKKSASDFPCLPKQVAWILATRRVFMYPELLPICSLKANPPRDKIIFTKAEDNLLALGLKHFEGTEFPKPLISKYLLPTKTAHQLTVRIKNLNMNRAPDNIIRHYKKTKQLPVLFKCCDEIQPNEWKPPVEREEHRLPFWLKASLPSIQGELKQLAEDAREVPGSTDEESDFLGTEKETSDTECGEKYPLLMPKGLVLTLKPLANRFSRRAWRRQKSSALKPVLIRPSPCLQPSSNTVNIQKTVKLSQSEAPPGKVMVQIPQLIQPATVVQAVPGVQPLNVPAVVGSGDGLEFQNVLSASHPDSRQGFSGAVPPALVSSSPVTFQPKLMLPDLAGTKIRKPCVRKVYQKKKGTKAAPLIKAPPLIQPSPVILTVPATTVKVVNIGNGCNMIQSINTAVGRGTQAIPVTTLLVNPSTFPCPLNQPLVTSSIPSLIVSPNPVGLSAPSVAESEEQLNLLPSCPAGNNKNSCPVVEPKAEPQELCVPCSAASPKKECSANPTASNNTSQEKVNKSDCCSWTMVKAEENVSEPLSVDLLPHLEDSDKTVKSEAEDSNDAVKEVNPVQKRNLLCVEVKEEFMLGLGQELNMEAACSCANELKEIKKEHALCEEKGGEEERRALQSSPRDEPQREAGAVGGAQACSESPKNHSSSVDVEAEFSSPLGRPEDSSSMDGQSVGTPAGPEAGGEREGQEEEEDDDFDDFTQDEDEEMSSASEESILSVPELQETMEKLTWLATERRLSQEGDSEEENSQEENSEPEEEEEEEGEGMESSQKDDEVCGDVSEEPKSAFTLTNMAPQVEAHRMPPGENMKAPGKSRSSHRARNKRGRARASKDTSKLLLLYDENILERDPLREQKDLAFAQAYLTRVREALQHIPGKYEDFLRVIYEFEISMDKQTAVDLYFTLQKLLHDWPQLLTDFAAFLLPEQALECGLFEEQQAFEKSRKFLRQLEICFAENPAHHQKIIKVLQSSVDCLPQEIAELKTQMWQLLKGHDHLQDEFSVFFDHLRPSASRMGDFEEINWTEEKEYEFDGFEEVSLPDVEEEDEPPKIHAAPKNKKRKEIGGQNNDKEAEWGDAMKECSCSCHEGSGELKLKKSKRRSCSHCSSKVCENKFYKNKDSQELSASLVQQESSPQPEGKDSGTSKEPAEENLENRDEGEDVQSRTRTVSRKGEPLPAGSQPEGRAVCSRHTSPDKAALPERRVQEGGVSAAKDSPFVAVPGWTRLQKAAPKLPQETKGSPCSAGSGSEGLKQQHQGDVDASLELSRDLLLSSRSATVKGSMRPGSSKNSLCQTEGLPSDSSDKFGHSSKLSAREFEGSPLPLEGKSEAKQSWITPARKPALGKSCCSPSPSNCALEADSMGCTGSVPENRLKSNANNCFQVHRHSEELEYRVCTASLGQKEEEQQQQRVTEATVCAKNSKVSSTGEKVVLWTREADRVILTTCQEKGAHLETFQAISQKLGNKTAAEVSHRFRELMKLFHTSCDGSSEDEEDATSTSNADQLSDKDLLLSEEEPDD", "length": 2215 }, "evidence": [ { "id": "A0AAA9TS91", "url": "https://omabrowser.org/oma/group/A0AAA9TS91/", "database": "OMA" } ], "glygen_name": "Chicken", "common_name": "Chicken" }, { "uniprot_canonical_ac": "F1QI87-1", "protein_name": "GON-4-like protein", "gene_name": "gon4lb", "tax_id": 7955, "organism": "Danio rerio", "sequence": { "sequence": "MGWKRKSSSPEPQPNLVKLPKRESLSRSPSSWKRKASTPSKTKSWTSIQSLSPDRHVDQCNGQEKMSSAGHVEDDSDCIQSSTPVSSPLRSEEDAELGLVITVDEDRCEGEEWLKKRNGVNIKKNGINQTEGEIPQKEDGDVEKTMEQLSEEDENEEELRKLDRDLTLKSKKLNLSSINVRNIIHEVVTNEHVVAMMKAAIKETQDMPMFEPKMTRSKLKEAVEKGVGMGNWNISPIKKANDIKPPQFVDIPLQEEEDSSDEEYCPDEDEEDETAEETFLESDVESTSSSPRGIRRFPSQTPPHCDDASNSPRLKPRLARHLRVEAVPMGPPAPPPQSCGLSRSLKTLDPFIEKLHAVDKELELSPLCMEPYQALSSGGAGEPDDSLVACRTRSKRPLRDVPLDQLEAELRAPDITPDMYDNVSTPEDREWTQWLQGLMTSHLDNDEEADEDDDPEYNFLDDLDEPDLEDYRNDRAVRITKKEVNELMEELFETFHDELAANEPDDEGHDEDEEREEEANDTPQFNVPQAIRFEEPLAHMLTACRRTVREQLDALQQRRENQVRTTQHASGPGMVFVQPSCPLVVTPAQRIQLQQQIQQHVQLLTQVSMLCDPVGALQTEAQTTKHFLGELLSFAERAEEERSAVNLGFKSVFRVCNLLSSINLLEEVKQSPSLSCLPPKPNRHHSVHSYPLLPAGLAWLFATRSVFLYPELLPHCSLDPALHPSRSKHYYSKGEDGLLVLGLKHFAQTEFPYQLISRYLIRPKRQEQLRMRVKDMVSPKYPHNIIKYYCQNHVVPPLPVVCKPVVHGEERPPVEREQEVMPNWLKKSLPLIQKSICQSDLTMTSTTKSASLPFPKETRYPQFLPKGLSLRLHPSQVASRPSQPKSRILRAFTNRTLAPLAKAPSCPTGTGHLLTNISTPVLLLAQAPSTPINGVFPLVHPSLTPAHGTVPLNASYPINFHYLSPELGASNPAHLPANLPPSVVQKPQCDVPLLSTGTVKTHGVQQQTSDKHKKRTMPRKLAPLRPAPQLPRLLPLSSGSIGNISNPGIIIDQQISLNVPHNLQSDNVIVIKAHENVNTHRTVPSLSPDLVVQLVPQTQVAENTTSSLPRKTTPRSDVSQTAKDIPSVQSSGENGQRTVFSPQTAAPAAVDSSQFVLVQTVSPTGPPQFLLLPQDSLVLNQPASLPSEGTLQNLSQQTSHLDISTTSTALKNSEKTEVHLNNPTTSLPVSREEDGERQEVDEEMVGDRWEEEMASALFGSPLLALSESSCSPDSSPDASMDSGSDAMVRVEMEDGELPSVHSASATQETPDVHKHSSGDEKEQQSSGGEKQNSGNEEGRAEESESRKDEAQDEDKGGEKNEDGEGDGKRDEGGSGDKGREEKDGDGEKDGDGERDEEEEDFDDLTQDEDEEEVMSSASEESVLSVPELQETMEKLTWLASERRLCREGDSEEDNSPTSPTSPTSPNSQNSPASQNSQEENSEDEDDGAMKGDELEAGEGEGEKLPEGDAPAGDDPPQISEKVGGRGRGRGRPPPRSLKRGRRQERGSKDASKLLLLYDDHILDNDPMRESKDMAYAQAYLNRVREALQDVPGKVEEFLGLLYEFDQAGESHSVIELFAQLKQLLKDWPELLKDFAAFLLPEQALECGLFEEQQAFERSRRFLRQLEISFGENPSHYQKIVRALQSGSPLSPAGIEELKTQMATLLKGHTHLQGEFWMFFDEMRPPPARPGQFEEAVWPEDVATGTDGEAGVSVTSRGGVWGGFEEVTLPDLDEDEESHKIRQISSRSKRRKELHTYKDCDWPEKDCSCSCHDSVHDAKHRRHKRKGCLRCQSNKAANGSKVLKGRDSAFSSADAQSERGGEEKEEERVLGEDGEAEKELKDETGSGANSPHHDGEGSVWEREERATSSIPEEQNTHNQDDEEKTEEKNHHASPEKHSRDEEDSAESGQTEAAQQSSLSPALDAPVCAKNISLTPTGERVILWTREADRVILTTCQQQGASQSTFQAVSEQLGNKTASEVSRRFRDLMRLFHTSASQASSEDEAAEQQSATDEEQD", "length": 2055 }, "evidence": [ { "id": "A0AAA9TS91", "url": "https://omabrowser.org/oma/group/A0AAA9TS91/", "database": "OMA" } ], "glygen_name": "Zebrafish", "common_name": "Zebrafish" }, { "uniprot_canonical_ac": "Q3T8J9-1", "protein_name": "GON-4-like protein", "gene_name": "GON4L", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MLPCKKRRTTVTESLQHKGNQEENNVDLESAVKPESDQVKDLSSVSLSWDPSHGRVAGFEVQSLQDAGNQLGMEDTSLSSGMLTQNTNVPILEGVDVAISQGITLPSLESFHPLNIHIGKGKLHATGSKRGKKMTLRPGPVTQEDRCDHLTLKEPFSGEPSEEVKEEGGKPQMNSEGEIPSLPSGSQSAKPVSQPRKSTQPDVCASPQEKPLRTLFHQPEEEIEDGGLFIPMEEQDNEESEKRRKKKKGTKRKRDGRGQEGTLAYDLKLDDMLDRTLEDGAKQHNLTAVNVRNILHEVITNEHVVAMMKAAISETEDMPMFEPKMTRSKLKEVVEKGVVIPTWNISPIKKANEIKPPQFVDIHLEEDDSSDEEYQPDDEEEDETAEESLLESDVESTASSPRGAKKSRLRQSSEMTETDEESGILSEAEKVTTPAIRHISAEVVPMGPPPPPKPKQTRDSTFMEKLHAVDEELASSPVCMDSFQPMDDSLIAFRTRSKMPLKDVPLGQLEAELQAPDITPDMYDPNTADDEDWKMWLGGLMNDDVGNEDEADDDDDPEYNFLEDLDEPDTEDFRTDRAVRITKKEVNELMEELFETFQDEMGFSNMEDDGPEEEECVAEPRPNFNTPQALRFEEPLANLLNEQHRTVKELFEQLKMKKSSAKQLQEVEKVKPQSEKVHQTLILDPAQRKRLQQQMQQHVQLLTQIHLLATCNPNLNPEATTTRIFLKELGTFAQSSIALHHQYNPKFQTLFQPCNLMGAMQLIEDFSTHVSIDCSPHKTVKKTANEFPCLPKQVAWILATSKVFMYPELLPVCSLKAKNPQDKIVFTKAEDNLLALGLKHFEGTEFPNPLISKYLLTCKTAHQLTVRIKNLNMNRAPDNIIKFYKKTKQLPVLGKCCEEIQPHQWKPPIEREEHRLPFWLKASLPSIQEELRHMADGAREVGNMTGTTEINSDRSLEKDNLELGSESRYPLLLPKGVVLKLKPVATRFPRKAWRQKRSSVLKPLLIQPSPSLQPSFNPGKTPARSTHSEAPPSKMVLRIPHPIQPATVLQTVPGVPPLGVSGGESFESPAALPAVPPEARTSFPLSESQTLLSSAPVPKVMLPSLAPSKFRKPYVRRRPSKRRGVKASPCMKPAPVIHHPASVIFTVPATTVKIVSLGGGCNMIQPVNAAVAQSPQTIPITTLLVNPTSFPCPLNQSLVASSVSPLIVSGNSVNLPIPSTPEDKAHVNVDIACAVADGENAFQGLEPKLEPQELSPLSATVFPKVEHSPGPPLADAECQEGLSENSACRWTVVKTEEGRQALEPLPQGIQESLNNPTPGDLEEIVKMEPEEAREEISGSPERDICDDIKVEHAVELDTGAPSEELSSAGEVTKQTVLQKEEERSQPTKTPSSSQEPPDEGTSGTDVNKGSSKNALSSMDPEVRLSSPPGKPEDSSSVDGQSVGTPVGPETGGEKNGPEEEEEEDFDDLTQDEEDEMSSASEESVLSVPELQETMEKLTWLASERRMSQEGESEEENSQEENSEPEEEEEEEAEGMESLQKEDEMTDEAVGDSAEKPPTFASPETAPEVETSRTPPGESIKAAGKGRNNHRARNKRGSRARASKDTSKLLLLYDEDILERDPLREQKDLAFAQAYLTRVREALQHIPGKYEDFLQVIYEFESSTQRRTAVDLYKSLQILLQDWPQLLKDFAAFLLPEQALACGLFEEQQAFEKSRKFLRQLEICFAENPSHHQKIIKVLQGCADCLPQEITELKTQMWQLLKGHDHLQDEFSIFFDHLRPAASRMGDFEEINWTEEKEYEFDGFEEVALPDVEEEEEPPKIPTASKNKRKKEIGVQNHDKETEWPDGAKDCACSCHEGGPDSKLKKSKRRSCSHCSSKVCDSKSYKSKEPHELVGSSPHREASPMPGAKEAGQGKDMMEEEAPEERESTEATQSRTVRTTRKGEMPVSAGLAVGSTLPSPREVTVTERLLLDGPPPHSPETPQFPPTTGAVLYTVKRNQVGPEVRSCPKASPRLQKEREGQKAVSESEALMLVWDASETEKLPGTVEPPASFLSPVSSKTRDAGRRHVSGKPDTQERWLPSSRARVKTRDRTCPVHESPSGIDTSETSPKAPRGGLAKDSGTQAKGPEGEQQPKAAEATVCANNSKVSSTGEKVVLWTREADRVILTMCQEQGAQPQTFNIISQQLGNKTPAEVSHRFRELMQLFHTACEASSEDEDDATSTSNADQLSDHGDLLSEEELDE", "length": 2241 }, "evidence": [ { "id": "A0AAA9TS91", "url": "https://omabrowser.org/oma/group/A0AAA9TS91/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "Q535K8-1", "protein_name": "GON-4-like protein", "gene_name": "Gon4l", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MLPCKKRSGVTESAQQQDDQEGEDLHLEAAVKPDTDQLPDCTSESLSWGQSHDSAGCPEVHSMQDVGSQLSVEGTPLSSKMLTQRVNLAVSEAVDVPVSQEIPVPSLESSHSLPVHMGKGRLQSTASRKGKKIAFMPGQVTREDGGDHTVPEEPPSGEHAEEVKAEGGELEMHSEGDLPSLSSGSQSAKPRAQPRKSFQPDGSAFPQEKSLGPLVRQAEEDMEDGGLFIPTEEQDGEESDKRKKTKKGTKRKRDGRGQEQGTMTYDPKVDDMLDRTLEDGAKQHNLTAVNVRNILHEVITNEHVVAMMKAAISETEDMPLFEPKMTRSKLKEVVEKGVVIPTWNISPIKKASETKQPPQFVDIHLEDDDSSDEEYQPDEEEEDETAEESLLESDVESAASSPRGVKRSRLRLSSEAAEADEESGVLSEVEKVATPALRHISAEVVPMGPPPPPKPKQTRDSTFMEKLNAVDEELAASPVCMDSFQPMEDSLIAFRTRSKMPLKDVPLGQLEAELQAPDITPDMYDPNTADDEDWKLWLGGLLNDDVENEDEADDDDDPEYNFLEDLDEPDTEDFRTDRAVRITKKEVNGLMEELFETVQSVVPSKFQDEMGFSNMEDDGPEEEERVTESRPSFNTPQALRFEEPLANLLNERHRTVKELLEQLKMKKSSVRQQPEVEKLKPQTEKVHQTLVLDPAQRSRLQQQMQQHVQLLTQIYLLTTSNPNLSSEASTTRVFLKELGTFAENSTALHQQFNPRFQTLFQPCNWVGAMQLIEDFTHISIDCSPHKTVKKTASEFPCLPKQVAWILATNKVFMYPELLPICSLKANNPRDKTIFTKAEDNLLALGLKHFEGTEFPKPLISKYLVTCKTAHQLTVRIKNLNLNRAPNNVIKFYKKTKQLPVLVRCCEEIQPHQWKPPIEKEEHRLPFWLKASLQSIQEELRNLAGGATAGGSVTAATETSTDQHLQKTSPVVGGDTQYPLLLPKGVVLKLKPGSKRFSRKAWRQKRPLVQKPLLIQPSPSVQPVFNPGKMATWPTQSEVPPSNTVVQIPHLIQPAAVLQTLPGFPSVGVCGEDSFESPAALPAMPSGSEARTSFPWSESQSAPPSSSAPKLMLPSLGPSKFRKPYVRRKPTRRKGAKASPCVKPAPIIHPTPVIFTVPATTVKVVSLGGGCNMIQPVTAAVAPSPQTIPITTLLVNPTSFPCSLNQPLVASSISPLLVSSNPLALPVTSLPEEKAHVSLDIAEGKNAPQNPEPKIKPQEPTPQCATVFSKEEPRSWHPSADTGNQEAVSESSACSWAAVKTEGQEGSSEKSVCGWTVVKTEDGGHAVQPLPQDPQDSLNSPSKDLLNMVKLEAEDCMEEISSDFPKQDIGEEVKEECCMELDRDSPQEKASSVSEMSKQTATPREETQAAKSPTVSQDAPDAIRDASKGLPQSTLSSMDQGTVLNSPPGKPEDSANADGQSVGTPAGTDTGAEKDGAEEEEEEDFDDLTQDEEDELSSASEESVLSVPELQETMEKLTWLASERRMSQEGESEEENSQEENSEPEEEEEEEAEGMETLQKEDEATDEAGGGAAEKPPSTLASPHTAPEVETSITPAGESIKAAGKGRSSHRARSRRGSRARASKDASKLLLLYDEDILDRDPLREQKDLAFAQAYLTRVREALQHIPGKYEDFLQIIYEFESNAQMHSAVDLFKSLQTLLHDWPQLLKDFAAFLLPEQALSCGLFEEQQAFEKSRKFLRQLEICFAENPSHHQKIIKVLQGCADCLPQDITELKTQMWQLLRGHDHLQDEFSIFFDHLRPAANRMGDFEEINWTEEKEYEFDGFEEVILPEVEEEEEPAKVSTASKSKRRKEIGVQHQDKESEWPEAAKDGSCPCHEGGPESKLKKSKRRNCHCSSKVCDSKSYKSKEPLELVGSGPLQEASTVPGTKEAGQGKDMSEEETMEGQENVEVSQNKTGRTTRKGEAPIPGSTVRTALLCSAEVTPIELSLEGPTCCSPETPRLPPQTGAVVCSVRRNQAGPEVVSCLGTSSIPPKEGEDQKAVANSETIAPLPETSETERLPGTVELPAPLPSPVSLSTRDTGRRHIYGKAGTQSWLLDNRAEAKAAHMVAPIRGTSSGASASEAAPTASREGLAEDSETQGKGPEAVLPKASEATVCANNSKVSSTGEKVVLWTREADRVILTMCQEQGAQPHTFSVISQQLGNKTPVEVSHRFRELMQLFHTACEASSEDEDDATSTSNADQLSDHGDLLSEEELDE", "length": 2256 }, "evidence": [ { "id": "A0AAA9TS91", "url": "https://omabrowser.org/oma/group/A0AAA9TS91/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" } ], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 1, "go_terms": [ { "name": "nucleus", "id": "GO:0005634", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005634", "evidence": [ { "database": "UniProtKB", "id": "A0AAA9TS91", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TS91" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 2, "go_terms": [ { "name": "DNA-templated transcription", "id": "GO:0006351", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006351", "evidence": [ { "database": "UniProtKB", "id": "A0AAA9TS91", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TS91" } ], "pmid": "" }, { "name": "regulation of DNA-templated transcription", "id": "GO:0006355", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006355", "evidence": [ { "database": "UniProtKB", "id": "A0AAA9TS91", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TS91" } ], "pmid": "" } ] }, { "name": "Molecular Function", "total": 2, "go_terms": [ { "name": "transcription corepressor activity", "id": "GO:0003714", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003714", "evidence": [ { "database": "UniProtKB", "id": "A0AAA9TS91", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TS91" } ], "pmid": "" }, { "name": "transcription coregulator activity", "id": "GO:0003712", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003712", "evidence": [ { "database": "UniProtKB", "id": "A0AAA9TS91", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TS91" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 1213, "end_pos": 1215, "annotation": "n_glycosylation_sequon" }, { "start_pos": 1789, "end_pos": 1791, "annotation": "n_glycosylation_sequon" }, { "start_pos": 2140, "end_pos": 2142, "annotation": "n_glycosylation_sequon" }, { "start_pos": 2185, "end_pos": 2187, "annotation": "n_glycosylation_sequon" }, { "start_pos": 285, "end_pos": 287, "annotation": "n_glycosylation_sequon" }, { "start_pos": 344, "end_pos": 346, "annotation": "n_glycosylation_sequon" }, { "start_pos": 943, "end_pos": 945, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A0AAA9TS91", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TS91" }, { "id": "PS50090", "database": "PROSITE", "url": "https://prosite.expasy.org/PS50090" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "Myb-like", "eco_id": "ECO_0000259", "start_pos": 2154, "end_pos": 2199, "start_aa": "Trp", "end_aa": "Val", "glycosite_overlap": [] } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" }, { "name": "homologset.oma", "label": "OMA Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 1213, "end_pos": 1215 }, { "start_pos": 1789, "end_pos": 1791 }, { "start_pos": 2140, "end_pos": 2142 }, { "start_pos": 2185, "end_pos": 2187 }, { "start_pos": 285, "end_pos": 287 }, { "start_pos": 344, "end_pos": 346 }, { "start_pos": 943, "end_pos": 945 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ], "tool_support": { "graph_view": "yes" } }, { "uniprot_canonical_ac": "A0AAA9TTJ4-1", "uniprot_ac": "A0AAA9TTJ4", "uniprot_id": "A0AAA9TTJ4_BOVIN", "mass": { "chemical_mass": 23796.0, "monoisotopic_mass": 23796.0 }, "refseq": {}, "gene_names": [ { "name": "HDGFL3", "type": "recommended", "evidence": [ { "id": "A0AAA9TTJ4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TTJ4" } ] } ], "protein_names": [ { "name": "HDGF like 3", "type": "synonym", "evidence": [ { "id": "A0AAA9TTJ4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TTJ4/entry#names_and_taxonomy" } ] } ], "function": [], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Bos taurus", "taxid": 9913, "evidence": [ { "database": "UniProtKB", "id": "A0AAA9TTJ4", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TTJ4" } ], "common_name": "Bovine", "glygen_name": "Bovine", "reference_species": "Bos taurus [9913]" } ], "gene": [ { "name": "HDGFL3", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TTJ4", "locus": { "chromosome": "21", "start_pos": 24921366, "end_pos": 24844064, "strand": "-", "evidence": [ { "database": "Ensembl Gene", "id": "ENSBTAG00000018527", "url": "https://www.ensembl.org/id/ENSBTAG00000018527" } ] } } ], "crossref": [ { "id": "A0AAA9TTJ4", "url": "https://alphafold.ebi.ac.uk/entry/A0AAA9TTJ4", "database": "AlphaFoldDB", "categories": [] }, { "id": "ENSBTAG00000018527", "url": "https://bgee.org/?page=gene&gene_id=ENSBTAG00000018527", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "cd20150", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd20150", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "784070", "url": "https://www.ncbi.nlm.nih.gov/gene/784070", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR000313", "url": "https://www.ebi.ac.uk/interpro/entry/IPR000313", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "bta:784070", "url": "https://www.genome.jp/dbget-bin/www_bget?bta:784070", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "THETXAI", "url": "https://omabrowser.org/oma/group/THETXAI/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "E1BHR3", "url": "https://www.orthodb.org/?gene=E1BHR3", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR12550", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR12550", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR12550:SF82", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR12550:SF82", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00855", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00855", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "A0AAA9SD32", "url": "https://www.uniprot.org/uniprotkb/A0AAA9SD32", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0AAA9SD32-1", "url": "https://www.uniprot.org/uniprotkb/A0AAA9SD32-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0AAA9TTJ4", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TTJ4", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0AAA9TTJ4-1", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TTJ4-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "E1BHR3", "url": "https://www.uniprot.org/uniprotkb/E1BHR3", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "E1BHR3-1", "url": "https://www.uniprot.org/uniprotkb/E1BHR3-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "SYGDPSSNPDCPARRIRKPSVTSVKWLALGGSHRIVKSRPRIDELPEGAVKPPANKYPIFFFGTHETAFLGPKDLFPYKEYKDKFGKSNKRKGFNEGLWEIENNPGVKFTGYQAIQQQSSSETEGEGGNTADASSEEEGDRVEEDGKGKRKSEKAGSKRKKSYTSKKSSKQSRKSPGDEDDKDCKEEENKSSSEGGDAGNDTRNTTSDLQKTSEGT", "length": 216, "header": "tr|A0AAA9TTJ4-1|A0AAA9TTJ4_BOVIN Isoform 1 of HDGF like 3 OS=Bos taurus OX=9913 GN=HDGFL3 PE=4 SV=1 CANONICAL=A0AAA9TTJ4-1" }, "isoforms": [ { "isoform_ac": "A0AAA9SD32-1", "url": "https://www.uniprot.org/uniprotkb/A0AAA9SD32/entry", "sequence": { "sequence": "KFAAIPPKCIFFVSLLFSCITSPGQIPKCNSIELKEIDELPEGAVKPPANKYPIFFFGTHETAFLGPKDLFPYKEYKDKFGKSNKRKGFNEGLWEIENNPGVKFTGYQAIQQQSSSETEGEGGNTADASSEEEGDRVEEDGKGKRKSEKAGSKRKKSYTSKKSSKQSRKSPGDEDDKDCKEEENKSSSEGGDAGNDTRNTTSDLQKTSEGT", "length": 211, "header": "tr|A0AAA9SD32-1|A0AAA9TTJ4_BOVIN Computationally mapped isoform of HDGF like 3 OS=Bos taurus OX=9913 GN=HDGFL3 PE=4 SV=1 CANONICAL=A0AAA9TTJ4-1" }, "locus": { "chromosome": "21", "start_pos": 24920143, "end_pos": 24895375, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000115305.1", "url": "https://www.ensembl.org/id/ENSBTAT00000115305.1" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000080225.1", "url": "https://www.ensembl.org/id/ENSBTAP00000080225.1" } ] } }, { "isoform_ac": "A0AAA9TTJ4-1", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TTJ4/entry", "sequence": { "sequence": "SYGDPSSNPDCPARRIRKPSVTSVKWLALGGSHRIVKSRPRIDELPEGAVKPPANKYPIFFFGTHETAFLGPKDLFPYKEYKDKFGKSNKRKGFNEGLWEIENNPGVKFTGYQAIQQQSSSETEGEGGNTADASSEEEGDRVEEDGKGKRKSEKAGSKRKKSYTSKKSSKQSRKSPGDEDDKDCKEEENKSSSEGGDAGNDTRNTTSDLQKTSEGT", "length": 216, "header": "tr|A0AAA9TTJ4-1|A0AAA9TTJ4_BOVIN Isoform 1 of HDGF like 3 OS=Bos taurus OX=9913 GN=HDGFL3 PE=4 SV=1 CANONICAL=A0AAA9TTJ4-1" }, "locus": { "chromosome": "21", "start_pos": 24920143, "end_pos": 24844334, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000115743.1", "url": "https://www.ensembl.org/id/ENSBTAT00000115743.1" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000099859.1", "url": "https://www.ensembl.org/id/ENSBTAP00000099859.1" } ] } }, { "isoform_ac": "E1BHR3-1", "url": "https://www.uniprot.org/uniprotkb/E1BHR3/entry", "sequence": { "sequence": "MARPRPREYKAGDLVFAKMKGYPHWPARIDELPEGAVKPPANKYPIFFFGTHETAFLGPKDLFPYKEYKDKFGKSNKRKGFNEGLWEIENNPGVKFTGYQAIQQQSSSETEGEGGNTADASSEEEGDRVEEDGKGKRKSEKAGSKRKKSYTSKKSSKQSRKSPGDEDDKDCKEEENKSSSEGGDAGNDTRNTTSDLQKTSEGT", "length": 203, "header": "tr|E1BHR3-1|A0AAA9TTJ4_BOVIN Computationally mapped isoform of HDGF like 3 OS=Bos taurus OX=9913 GN=HDGFL3 PE=4 SV=3 CANONICAL=A0AAA9TTJ4-1" }, "locus": { "chromosome": "21", "start_pos": 24920143, "end_pos": 24845442, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000024660.6", "url": "https://www.ensembl.org/id/ENSBTAT00000024660.6" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000024660.6", "url": "https://www.ensembl.org/id/ENSBTAP00000024660.6" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [ { "id": "bta:784070", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?bta:784070", "resource": "KEGG Pathway" } ], "orthologs": [ { "uniprot_canonical_ac": "A0A287AQQ1-1", "protein_name": "HDGF like 3", "gene_name": "HDGFL3", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MAVREPAAVRGGKSWKGVVVIQSQQEPSWPSFIHLPVHPSPIDELPEGAVKPPANKYPIFFFGTHETAFLGPKDLFPYKEYKDKFGKSNKRKGFNEGLWEIENNPGVKFTGYQAIQQQSSSETEGEGGNTADASSEEEGDRVEEDGKGKRKNEKAGSKRKKSYTSKKSSKQSRKSPGDEDDKDCKEEENKSSSEGGDAGNDTRNTTSDLQKTSEGT", "length": 216 }, "evidence": [ { "id": "A0AAA9TTJ4", "url": "https://omabrowser.org/oma/group/A0AAA9TTJ4/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "A0A8V0YQX7-1", "protein_name": "HDGF like 3", "gene_name": "HDGFRP3", "tax_id": 9031, "organism": "Gallus gallus", "sequence": { "sequence": "MKLKKMVFLWHTFVCVPRCLALRLSLLCRLPLSISAACLSVSDGQPVCHKTWGCLVALWPFLVCPVWPTWPELLQIDELPEGAVKPPANKYPIFFFGTHETAFLGPKDLFPYKEYKDKFGKSNKRKGFNEGLWEIENNPGVKFTGYQAIQQQSSSETEGEGGNTADASSEEEGDRVEEDGKGKRKNEKAGSKRKKSYTSKKSSKQSRKSPGDEDDKDCKEEENKSSSDAGDAGNDTRNTSSDLQKTSEGT", "length": 250 }, "evidence": [ { "id": "A0AAA9TTJ4", "url": "https://omabrowser.org/oma/group/A0AAA9TTJ4/", "database": "OMA" } ], "glygen_name": "Chicken", "common_name": "Chicken" }, { "uniprot_canonical_ac": "Q923W4-1", "protein_name": "Hepatoma-derived growth factor-related protein 3", "gene_name": "Hdgfl3", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MARPRPREYKAGDLVFAKMKGYPHWPARIDELPEGAVKPPANKYPIFFFGTHETAFLGPKDLFPYKEYKDKFGKSNKRKGFNEGLWEIENNPGVKFTGYQTIQQQSSSETEGEGGNTADASSEEEGDRVEDGKGKRKNEKGGSKRKKSYTSKKSSKQSRKSPGDEDDKDCKEEENKSSSEGGDAGNDTRNTTSDLQKAGEGT", "length": 202 }, "evidence": [ { "id": "A0AAA9TTJ4", "url": "https://omabrowser.org/oma/group/A0AAA9TTJ4/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "Q9JMG7-1", "protein_name": "Hepatoma-derived growth factor-related protein 3", "gene_name": "Hdgfl3", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MARPRPREYKAGDLVFAKMKGYPHWPARIDELPEGAVKPPANKYPIFFFGTHETAFLGPKDLFPYKEYKDKFGKSNKRKGFNEGLWEIENNPGVKFTGYQTIQQQSSSETEGEGGNTADASSEEEGDRVEDGKGKRKNEKGGSKRKKSYTSKKSSKQSRKSPGDEDDKDCKEEENKSSSEGGDAGNDTRNTTADLQKAGEGT", "length": 202 }, "evidence": [ { "id": "A0AAA9TTJ4", "url": "https://omabrowser.org/oma/group/A0AAA9TTJ4/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q9Y3E1-1", "protein_name": "Hepatoma-derived growth factor-related protein 3", "gene_name": "HDGFL3", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MARPRPREYKAGDLVFAKMKGYPHWPARIDELPEGAVKPPANKYPIFFFGTHETAFLGPKDLFPYKEYKDKFGKSNKRKGFNEGLWEIENNPGVKFTGYQAIQQQSSSETEGEGGNTADASSEEEGDRVEEDGKGKRKNEKAGSKRKKSYTSKKSSKQSRKSPGDEDDKDCKEEENKSSSEGGDAGNDTRNTTSDLQKTSEGT", "length": 203 }, "evidence": [ { "id": "A0AAA9TTJ4", "url": "https://omabrowser.org/oma/group/A0AAA9TTJ4/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" } ], "go_annotation": { "categories": [ { "name": "Biological Process", "total": 3, "go_terms": [ { "name": "microtubule polymerization", "id": "GO:0046785", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0046785", "evidence": [ { "database": "UniProtKB", "id": "A0AAA9TTJ4", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TTJ4" } ], "pmid": "" }, { "name": "neuron projection development", "id": "GO:0031175", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0031175", "evidence": [ { "database": "UniProtKB", "id": "A0AAA9TTJ4", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TTJ4" } ], "pmid": "" }, { "name": "negative regulation of microtubule depolymerization", "id": "GO:0007026", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007026", "evidence": [ { "database": "UniProtKB", "id": "A0AAA9TTJ4", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TTJ4" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 2, "go_terms": [ { "name": "nucleoplasm", "id": "GO:0005654", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005654", "evidence": [ { "database": "UniProtKB", "id": "A0AAA9TTJ4", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TTJ4" } ], "pmid": "" }, { "name": "cytosol", "id": "GO:0005829", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005829", "evidence": [ { "database": "UniProtKB", "id": "A0AAA9TTJ4", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TTJ4" } ], "pmid": "" } ] }, { "name": "Molecular Function", "total": 1, "go_terms": [ { "name": "microtubule binding", "id": "GO:0008017", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008017", "evidence": [ { "database": "UniProtKB", "id": "A0AAA9TTJ4", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TTJ4" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 189, "end_pos": 191, "annotation": "n_glycosylation_sequon" }, { "start_pos": 200, "end_pos": 202, "annotation": "n_glycosylation_sequon" }, { "start_pos": 204, "end_pos": 206, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A0AAA9TTJ4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TTJ4" }, { "id": "PF00855", "database": "Pfam", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00855" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "PWWP", "eco_id": "ECO_0000259", "start_pos": 50, "end_pos": 104, "start_aa": "Val", "end_aa": "Asn", "glycosite_overlap": [] } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" }, { "name": "homologset.oma", "label": "OMA Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 189, "end_pos": 191 }, { "start_pos": 200, "end_pos": 202 }, { "start_pos": 204, "end_pos": 206 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ], "tool_support": { "graph_view": "yes" } }, { "uniprot_canonical_ac": "A0AAA9TVW9-1", "uniprot_ac": "A0AAA9TVW9", "uniprot_id": "A0AAA9TVW9_BOVIN", "mass": { "chemical_mass": 209007.0, "monoisotopic_mass": 209007.0 }, "refseq": {}, "gene_names": [ { "name": "EFCAB3", "type": "recommended", "evidence": [ { "id": "A0AAA9TVW9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TVW9" } ] } ], "protein_names": [ { "name": "EF-hand calcium binding domain 3", "type": "synonym", "evidence": [ { "id": "A0AAA9TVW9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TVW9/entry#names_and_taxonomy" } ] } ], "function": [], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Bos taurus", "taxid": 9913, "evidence": [ { "database": "UniProtKB", "id": "A0AAA9TVW9", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TVW9" } ], "common_name": "Bovine", "glygen_name": "Bovine", "reference_species": "Bos taurus [9913]" } ], "gene": [ { "name": "EFCAB3", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TVW9", "locus": { "chromosome": "19", "start_pos": 46862871, "end_pos": 46771087, "strand": "-", "evidence": [ { "database": "Ensembl Gene", "id": "ENSBTAG00000006943", "url": "https://www.ensembl.org/id/ENSBTAG00000006943" } ] } } ], "crossref": [ { "id": "A0AAA9TVW9", "url": "https://alphafold.ebi.ac.uk/entry/A0AAA9TVW9", "database": "AlphaFoldDB", "categories": [] }, { "id": "ENSBTAG00000006943", "url": "https://bgee.org/?page=gene&gene_id=ENSBTAG00000006943", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "cd00051", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd00051", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "524320", "url": "https://www.ncbi.nlm.nih.gov/gene/524320", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR002048", "url": "https://www.ebi.ac.uk/interpro/entry/IPR002048", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR011992", "url": "https://www.ebi.ac.uk/interpro/entry/IPR011992", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR018247", "url": "https://www.ebi.ac.uk/interpro/entry/IPR018247", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "AYMNRNT", "url": "https://omabrowser.org/oma/group/AYMNRNT/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "F1N057", "url": "https://www.orthodb.org/?gene=F1N057", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR22656", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR22656", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR22656:SF1", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR22656:SF1", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF13833", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF13833", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "A0AAA9SD85", "url": "https://www.uniprot.org/uniprotkb/A0AAA9SD85", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0AAA9SD85-1", "url": "https://www.uniprot.org/uniprotkb/A0AAA9SD85-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0AAA9TEH5", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TEH5", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0AAA9TEH5-1", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TEH5-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0AAA9TQJ2", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TQJ2", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0AAA9TQJ2-1", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TQJ2-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0AAA9TVW9", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TVW9", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0AAA9TVW9-1", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TVW9-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "F1N057", "url": "https://www.uniprot.org/uniprotkb/F1N057", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "F1N057-1", "url": "https://www.uniprot.org/uniprotkb/F1N057-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MNNLPVDKGKVYQKRLLNGIKFLKGGKIDSSKVYTILENMDMNLTEKELKDLIQNLPVDVNGKVDLEKVMNEVKPFSGDRVDTSKLENVLGNLGIKLTSNERLNLLETLPVNADGKVYQKRLMKGIKSLKRGNIDVNKLDTFLESMGIKITEEEFMDLIEKLPYDDEEDIKVDTVMKELSTVLGKQINVSDLKNALKDMKVEVTDKEYLNLVKTLPVDGGKIDMTNLVTFLENMGIELSHKELEDFSQNLPVDVDGKVDLKNVTLSMKDFTGEKINASDLKNVLGDMGIEVNDKECLELLKLLPIDGDKKVFQNRLLAALKSFKGGKVDVNNLNPVLGSMRIKLRNKELKSVVEKQPIDADGNVPLKKVMSDIKAVTGEKINVEDLKNILEGFGIEFTPKEYSELVKNLPVDDDGNIYENRLLDGVKSFNGGKVDVSNLENVLGNMKIKFPDNKLKDLAQNLPVDVFGKTDLHKLLKEIKKITGEKVEAKDIQKTLRNLGIELTNREIWELLKILPFADDKKVEKNDLLNHIKAFPGGKCHVSKLETILENLGYDLENEEVEDLRNHLPVDDEKVKPNTLMENVESFKGAKINADEVDGVLKNIGIELTPKERWKLLKTLPLTYDRKYYQKRLLQGLKTFQGGYVLENKLGTTLTNLNYELENKELNDLRNYLEIDNNGKVPLNSLMNTASLFSGNKINAKDTQFYLENIGIELTKSESEELLDALPLDENQMVYKNRLMDGVKKYRGGKVNIDKIDDALKNLGFPLDEEDIEELCSHLPIDVERRVKLDRLLDEVQELLGEVLDHNDLGNLLKDIGLRDQLKENSVLRKSLPLDAAGKLYKHKLLDSIKSLKGVDLNVNKLDSFMENMGFKIEEEEHKDLLNNLPMDDEGKVDVSVVMDEGNFFTGEKVDNSNLENFLENMGIELTEDKGMELLNNLPVDAKRRVYMNRLMKELRSLEGTKVSSDKVDICLKNMGIELTEEEIQELKDHLPVDDNEKIDLNVLTDKVKNITGEKIHTEDLKNVLKNMGIEITKKEHKKLIKTLPVSADKKVFKKELLRGVKSFKGGKVTVSDLSNVLQNTGFKLEAKEIQDLQTHLPITEDEEVGLDVLMDAANTFTGDKVEASNFKTVLGNMGLQLTEKEQFLLSKTLPISRDGKVYKKRLLNSVKPLKGKKISVNKLDTLMKNMGIQPEKEDYEDFLTHLPVDETQMVDLDVAMDDAKAFIGEKVTVSDLDNVMRRMGLALTTEEQKELLKTLPVHADGKVFKNRLLKSVKALKAPRVKIKKLESFVENMGVKLKDEELEELMTQLSADGNSTVGLNDLMDAISYIKGEVIDIPDLDNFLMSKGIELNEEEMKKLMPHLIFNEHGKVKVHSIMDGLKKIKRMGSLQKLMKITDDTKDRVTGPMAVSEIKAKFKLNPLTKVPNFHSRRDKDLPGLLPCQLQHKERKLSPSQMRAFQDAYNFFNKDKTGCIDLHGMMCTLAKLGMNLTKHDVHNELRCADIDQDGKVNFSDFLKVLTDKNRFLKAVVPEKGTCLDLAGNPGILLFEILSKLIETSALPKKAISEIVSYFRRKFQETTSGMVWSPDTTGYGKRRFKPDICTPPSSSTAAFANAARIAIMKEKDLFKFLDELKKCNPPSDSPYSKIPIFPLFPNVDGVVMGKPFKDIQKLEMLKRKEPLNFFENYFFHKKDWKTQAANIKPVDPTSGYSTDILTIDQMLKRKQNWTVADAAAIKPHVKRATETYNLGIALEHRKQMLNLWRKIRGDLIGIESKNESFYDTFSTYTWSWNVCQELLSPKDLKLYDAHVNRNALHNSVFSSSSDISECDTDTGRKRKRKGFKGFRQ", "length": 1843, "header": "tr|A0AAA9TVW9-1|A0AAA9TVW9_BOVIN Isoform 1 of EF-hand calcium binding domain 3 OS=Bos taurus OX=9913 GN=EFCAB3 PE=4 SV=2 CANONICAL=A0AAA9TVW9-1" }, "isoforms": [ { "isoform_ac": "A0AAA9SD85-1", "url": "https://www.uniprot.org/uniprotkb/A0AAA9SD85/entry", "sequence": { "sequence": "MDAISYIKEVIDIPDLDNFLMSKGIELNEEEMKKLMPHLIFNDRVTGPMAVSEIKAKFKLNPLTKVPNFHSRRDKDLPGLLPCQLQHKERKLSPSQMRAFQDAYNFFNKDKTGCIDLHGMMCTLAKLGMNLTKHDVHNELRCADIDQDGKVNFSDFLKVLTDKNRFLKAVVPEKGTCLDLAGNPGILLFEILSKLIETSALPKKAISEIVSYFRRKFQETTSGMVWSPDTTGYGKRRFKPDICTPPSSSTAAFANAARIAIMKEKDLFKFLDELKKCNPPSDSPYSKIPIFPLFPNVDGVVMGKPFKDIQKLEMLKRKEPLNFFENYFFHKKDWKTQAANIKPVDPTSGYSTDILTIDQMLKRKQNWTVADAAAIKPHVKRATETYNLGIALEHRKQMLNLWRKIRGDLIGIESKNESFYDTFSTYTWSWNVCQELLSPKDLKLYDAHVNRNALHNSVFSSSSDISECDTDTGRKRKRKGFKGFRQ", "length": 486, "header": "tr|A0AAA9SD85-1|A0AAA9TVW9_BOVIN Computationally mapped isoform of EF-hand calcium binding domain 3 OS=Bos taurus OX=9913 GN=EFCAB3 PE=4 SV=1 CANONICAL=A0AAA9TVW9-1" }, "locus": { "chromosome": "19", "start_pos": 46862731, "end_pos": 46813605, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000098638.1", "url": "https://www.ensembl.org/id/ENSBTAT00000098638.1" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000080285.1", "url": "https://www.ensembl.org/id/ENSBTAP00000080285.1" } ] } }, { "isoform_ac": "A0AAA9TEH5-1", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TEH5/entry", "sequence": { "sequence": "MDAISYIKEVIDIPDLDNFLMSKGIELNEEEMKKLMPHLIFNEHGKVKVHSIMDGLKKIKRMGSLQKLMKITDDTKDRVTGPMAVSEIKAKFKLNPLTKVPNFHSRRDKDLPGLLPCQLQHKERKLSPSQMRAFQDAYNFFNKDKTGCIDLHGMMCTLAKLGMNLTKHDVHNELRCADIDQDGKVNFSDFLKVLTDKNRFLKAVVPEKGTCLDLAGNPGILLFEILSKLIETSALPKKAISEIVSYFRRKFQETTSGMVWSPDTTGYGKRRFKPDICTPPSSSTAAFANAARIAIMKEKDLFKFLDELKKCNPPSDSPYSKIPIFPLFPNVDGVVMGKPFKDIQKLEMLKRKEPLNFFENYFFHKKDWKTQAANIKPVDPTSGYSTDILTIDQMLKRKQNWTVADAAAIKPHVKRATETYNLGIALEHRKQMLNLWRKIRGDLIGIESKNESFYDTFSTYTWSWNVCQELLSPKDLKLYDAHVNRNALHNSVFSSSSDISECDTDTGRKRKRKGFKGFRQ", "length": 520, "header": "tr|A0AAA9TEH5-1|A0AAA9TVW9_BOVIN Computationally mapped isoform of EF-hand calcium binding domain 3 OS=Bos taurus OX=9913 GN=EFCAB3 PE=4 SV=1 CANONICAL=A0AAA9TVW9-1" }, "locus": { "chromosome": "19", "start_pos": 46862731, "end_pos": 46813605, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000118201.1", "url": "https://www.ensembl.org/id/ENSBTAT00000118201.1" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000097015.1", "url": "https://www.ensembl.org/id/ENSBTAP00000097015.1" } ] } }, { "isoform_ac": "A0AAA9TQJ2-1", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TQJ2/entry", "sequence": { "sequence": "MRIKLRNKELKSVVEKQPIDADGNVPLKKVMSDIKAVTGEKINVEDLKNILEGFGIEFTPKEYSELVKNLPVDDDGNIYENRLLDGVKSFNGGKVDVSNLENVLGNMKIKFPDNKLKDLAQNLPVDVFGKTDLHKLLKEIKKITGEKVEAKDIQKTLRNLGIELTNREIWELLKILPFADDKKVEKNDLLNHIKAFPGGKCHVSKLETILENLGYDLENEEVEDLRNHLPVDDEKVKPNTLMENVESFKGAKINADEVDGVLKNIGIELTPKERWKLLKTLPLTYDRKYYQKRLLQGLKTFQGGYVLENKLGTTLTNLNYELENKELNDLRNYLEIDNNGKVPLNSLMNTASLFSGNKINAKDTQFYLENIGIELTKSESEELLDALPLDENQMVYKNRLMDGVKKYRGGKVNIDKIDDALKNLGFPLDEEDIEELCSHLPIDVERRVKLDRLLDEVQELLGEVLDHNDLGNLLKDIGLRDQLKENSVLRKSLPLDAAGKLYKHKLLDSIKSLKGVDLNVNKLDSFMENMGFKIEEEEHKDLLNNLPMDDEGKVDVSVVMDEGNFFTGEKVDNSNLENFLENMGIELTEDKGMELLNNLPVDAKRRVYMNRLMKELRSLEGTKVSSDKVDICLKNMGIELTEEEIQELKDHLPVDDNEKIDLNVLTDKVKNITGEKIHTEDLKNVLKNMGIEITKKEHKKLIKTLPVSADKKVFKKELLRGVKSFKGGKVTVSDLSNVLQNTGFKLEAKEIQDLQTHLPITEDEEVGLDVLMDAANTFTGDGKVYKKRLLNSVKPLKGKKISVNKLDTLMKNMGIQPEKEDYEDFLTHLPVDETQMVDLDVAMDDAKAFIGEKVTVSDLDNVMRRMGLALTTEEQKELLKTLPVHADGKVFKNRLLKSVKALKAPRVKIKKLESFVENMGVKLKDEELEELMTQLSADGNSTVGLNDLMDAISYIKGEVIDIPDLDNFLMSKGIELNEEEMKKLMPHLIFNEHGKVKVHSIMDGLKKIKRMGSLQKLMKITDDTKDRVTGPMAVSEIKAKFKLNPLTKVPNFHSRRDKDLPGLLPCQLQHKERKLSPSQMRAFQDAYNFFNKDKTGCIDLHGMMCTLAKLGMNLTKHDVHNELRCADIDQDGKVNFSDFLKVLTDKNRFLKAVVPEKGTCLDLAGNPGILLFEILSKLIETSALPKKAISEIVSYFRRKFQETTSGMVWSPDTTGYGKRRFKPDICTPPSSSTAAFANAARIAIMKEKDLFKFLDELKKCNPPSDSPYSKIPIFPLFPNVDGVVMGKPFKDIQKLEMLKRKEPLNFFENYFFHKKDWKTQAANIKPVDPTSGYSTDILTIDQMLKRKQNWTVADAAAIKPHVKRATETYNLGIALEHRKQMLNLWRKIRGDLIGIESKNESFYDTFSTYTWSWNVCQELLSPKDLKLYDAHVNRNALHNSVFSSSSDISECDTDTGRKRKRKGFKGFRQ", "length": 1469, "header": "tr|A0AAA9TQJ2-1|A0AAA9TVW9_BOVIN Computationally mapped isoform of EF-hand calcium binding domain 3 OS=Bos taurus OX=9913 GN=EFCAB3 PE=4 SV=2 CANONICAL=A0AAA9TVW9-1" }, "locus": { "chromosome": "19", "start_pos": 46862731, "end_pos": 46709584, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000094054.2", "url": "https://www.ensembl.org/id/ENSBTAT00000094054.2" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000098687.2", "url": "https://www.ensembl.org/id/ENSBTAP00000098687.2" } ] } }, { "isoform_ac": "A0AAA9TVW9-1", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TVW9/entry", "sequence": { "sequence": "MNNLPVDKGKVYQKRLLNGIKFLKGGKIDSSKVYTILENMDMNLTEKELKDLIQNLPVDVNGKVDLEKVMNEVKPFSGDRVDTSKLENVLGNLGIKLTSNERLNLLETLPVNADGKVYQKRLMKGIKSLKRGNIDVNKLDTFLESMGIKITEEEFMDLIEKLPYDDEEDIKVDTVMKELSTVLGKQINVSDLKNALKDMKVEVTDKEYLNLVKTLPVDGGKIDMTNLVTFLENMGIELSHKELEDFSQNLPVDVDGKVDLKNVTLSMKDFTGEKINASDLKNVLGDMGIEVNDKECLELLKLLPIDGDKKVFQNRLLAALKSFKGGKVDVNNLNPVLGSMRIKLRNKELKSVVEKQPIDADGNVPLKKVMSDIKAVTGEKINVEDLKNILEGFGIEFTPKEYSELVKNLPVDDDGNIYENRLLDGVKSFNGGKVDVSNLENVLGNMKIKFPDNKLKDLAQNLPVDVFGKTDLHKLLKEIKKITGEKVEAKDIQKTLRNLGIELTNREIWELLKILPFADDKKVEKNDLLNHIKAFPGGKCHVSKLETILENLGYDLENEEVEDLRNHLPVDDEKVKPNTLMENVESFKGAKINADEVDGVLKNIGIELTPKERWKLLKTLPLTYDRKYYQKRLLQGLKTFQGGYVLENKLGTTLTNLNYELENKELNDLRNYLEIDNNGKVPLNSLMNTASLFSGNKINAKDTQFYLENIGIELTKSESEELLDALPLDENQMVYKNRLMDGVKKYRGGKVNIDKIDDALKNLGFPLDEEDIEELCSHLPIDVERRVKLDRLLDEVQELLGEVLDHNDLGNLLKDIGLRDQLKENSVLRKSLPLDAAGKLYKHKLLDSIKSLKGVDLNVNKLDSFMENMGFKIEEEEHKDLLNNLPMDDEGKVDVSVVMDEGNFFTGEKVDNSNLENFLENMGIELTEDKGMELLNNLPVDAKRRVYMNRLMKELRSLEGTKVSSDKVDICLKNMGIELTEEEIQELKDHLPVDDNEKIDLNVLTDKVKNITGEKIHTEDLKNVLKNMGIEITKKEHKKLIKTLPVSADKKVFKKELLRGVKSFKGGKVTVSDLSNVLQNTGFKLEAKEIQDLQTHLPITEDEEVGLDVLMDAANTFTGDKVEASNFKTVLGNMGLQLTEKEQFLLSKTLPISRDGKVYKKRLLNSVKPLKGKKISVNKLDTLMKNMGIQPEKEDYEDFLTHLPVDETQMVDLDVAMDDAKAFIGEKVTVSDLDNVMRRMGLALTTEEQKELLKTLPVHADGKVFKNRLLKSVKALKAPRVKIKKLESFVENMGVKLKDEELEELMTQLSADGNSTVGLNDLMDAISYIKGEVIDIPDLDNFLMSKGIELNEEEMKKLMPHLIFNEHGKVKVHSIMDGLKKIKRMGSLQKLMKITDDTKDRVTGPMAVSEIKAKFKLNPLTKVPNFHSRRDKDLPGLLPCQLQHKERKLSPSQMRAFQDAYNFFNKDKTGCIDLHGMMCTLAKLGMNLTKHDVHNELRCADIDQDGKVNFSDFLKVLTDKNRFLKAVVPEKGTCLDLAGNPGILLFEILSKLIETSALPKKAISEIVSYFRRKFQETTSGMVWSPDTTGYGKRRFKPDICTPPSSSTAAFANAARIAIMKEKDLFKFLDELKKCNPPSDSPYSKIPIFPLFPNVDGVVMGKPFKDIQKLEMLKRKEPLNFFENYFFHKKDWKTQAANIKPVDPTSGYSTDILTIDQMLKRKQNWTVADAAAIKPHVKRATETYNLGIALEHRKQMLNLWRKIRGDLIGIESKNESFYDTFSTYTWSWNVCQELLSPKDLKLYDAHVNRNALHNSVFSSSSDISECDTDTGRKRKRKGFKGFRQ", "length": 1843, "header": "tr|A0AAA9TVW9-1|A0AAA9TVW9_BOVIN Isoform 1 of EF-hand calcium binding domain 3 OS=Bos taurus OX=9913 GN=EFCAB3 PE=4 SV=2 CANONICAL=A0AAA9TVW9-1" }, "locus": { "chromosome": "19", "start_pos": 46862731, "end_pos": 46674378, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000114526.2", "url": "https://www.ensembl.org/id/ENSBTAT00000114526.2" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000102766.2", "url": "https://www.ensembl.org/id/ENSBTAP00000102766.2" } ] } }, { "isoform_ac": "F1N057-1", "url": "https://www.uniprot.org/uniprotkb/F1N057/entry", "sequence": { "sequence": "MAVSEIKAKFKLNPLTKVPNFHSRRDKDLPGLLPCQLQHKERKLSPSQMRAFQDAYNFFNKDKTGCIDLHGMMCTLAKLGMNLTKHDVHNELRCADIDQDGKVNFSDFLKVLTDKNRFLKAVVPEKGTCLDLAGNPGILLFEILSKLIETSALPKKAISEIVSYFRRKFQETTSGMVWSPDTTGYGKRRFKPDICTPPSSSTAAFANAARIAIMKEKDLFKFLDELKKCNPPSDSPYSKIPIFPLFPNVDGVVMGKPFKDIQKLEMLKRKEPLNFFENYFFHKKDWKTQAANIKPVDPTSGYSTDILTIDQMLKRKQNWTVADAAAIKPHVKRATETYNLGIALEHRKQMLNLWRKIRGDLIGIESKNESFYDTFSTYTWSWNVCQELLSPKDLKLYDAHVNRNALHNSVFSSSSDISECDTDTGRKRKRKGFKGFRQ", "length": 438, "header": "tr|F1N057-1|A0AAA9TVW9_BOVIN Computationally mapped isoform of EF-hand calcium binding domain 3 OS=Bos taurus OX=9913 GN=EFCAB3 PE=4 SV=1 CANONICAL=A0AAA9TVW9-1" }, "locus": { "chromosome": "19", "start_pos": 46862731, "end_pos": 46831054, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000009115.6", "url": "https://www.ensembl.org/id/ENSBTAT00000009115.6" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000009115.5", "url": "https://www.ensembl.org/id/ENSBTAP00000009115.5" } ] } } ], "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "other", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 1704, "start_aa": "Thr", "end_pos": 1704, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr1704", "evidence": [ { "id": "", "database": "GlyGen", "url": "https://data.glygen.org/" } ], "filter_code": "000000000000000010000.00000000001000.0.01000" } ], "phosphorylation": [], "glycation": [], "keywords": [ "glycoprotein", "glycoprotein_predicted" ], "publication": [], "pathway": [], "orthologs": [ { "uniprot_canonical_ac": "A0A8C2MK99-1", "protein_name": "EF-hand calcium-binding domain-containing protein 3", "gene_name": "Efcab3", "tax_id": 10029, "organism": "Cricetulus griseus", "sequence": { "sequence": "MAVSGIKTTLKLKPLRAPIFHRRDIDFRGSLLGQVYHKESKLNPSQLEAFRNAYSFFIRDKTGCIDSHGLMATLAKLGMNLTTYDIYNELKCADIDRDGKINFSDFIEVLTDKKLFLKAVVPERKLCLDLANNPGILLFEILSKLVETSSLNRRDIIELVSYFRKKFRESYTEILSSPYSKRGFKADVCTPPRSSTAAFANSARVSIMKEKDLYKFLEALKRCDLPSGSPYSKIPIFPLFPDLDSTVMGRPFKDIQKLETLKRKEPLSFFEDYFFHKRDWKAQAATVKPIKSASGYSDDILAIDQLFKKKQHWTVADAVAIKQHVKRATDTYNLGIALEHRKEMLNLWKKIRGDLIGIETNNESFYNTFSTYTWSWNVCQELLSAKDLRLHDAYMNRSSSGNSRLSTPSDLSECDPETGRKRRWKGFRGFRQ", "length": 432 }, "evidence": [ { "id": "A0AAA9TVW9", "url": "https://omabrowser.org/oma/group/A0AAA9TVW9/", "database": "OMA" } ], "glygen_name": "Hamster", "common_name": "Chinese hamster" }, { "uniprot_canonical_ac": "Q66HC0-1", "protein_name": "EF-hand calcium-binding domain-containing protein 3", "gene_name": "Efcab3", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MAISGFKGTLKLKPLKTPVFYKRDKDFRGYFSGHLQHKETKLSPAQLEAFRNAYNFFTKDRTGCIDSHGLMSTVAKLGMNLNAYDIYNELKCADRDRDGKINFSDFIDVLTDKKLFLKAVVPEKRICLDLANNPGILLFEILSKFVEISALHRKDIIELVSYFRKKFQESNSEILWSPYGRRAFKTDICSPPRSSTAAFANSARISIMKERDLYKFLEALKRCNLRTDSPYSKIPVFPLFPDVDGVVLGKPFKDTQKLEMLRKREPLSFFEDYFFNKRDWKTQAMNVKPLKSASGYSDDILAIDQLFKKKQHWTVSDAVALKQHVKRATDTYHLGIALDHRKEMLNLWKKIRGDLVGLESNNESFYNTFSTYTWSWNVCQELLSAKDLRLHDANVNKTSPSNSGLSSPSDLSESDPETGRKRKRKSSRGFRQ", "length": 432 }, "evidence": [ { "id": "A0AAA9TVW9", "url": "https://omabrowser.org/oma/group/A0AAA9TVW9/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "Q80X60-1", "protein_name": "EF-hand calcium-binding domain-containing protein 3", "gene_name": "Efcab3", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MAVSEIKATMKLKPLKAPVFHKRDKDLRGSFSDHLKHKESKLSPAQLEAFRNAYNFFTKDRTGCIDSHGLISTIAKLGMNLNTYDIYNELKCADLDRDGKINFSDFINVLTDKKLFLKAVVPEKKICLDLANNPGILLFEILSKFVETSSLHRKDIIELVSYFRKRFQESHSEIMWSSYGRRGLKSEICSPPRSSTAAFANSARISIMKERDLYKFLEALKRCNLRTDSPYSKIPVFPLFPDVDGTVMGKPFKDTQKIEMLRRKEPLTFFEDYFFNKRDWKTQAMNVKPLKSASGYSDDILAIDHLFKKKQHWTVTDAAAIKQHVKKATESYNLGIALDHRKEMLNLWKKIRGDLVGIESNNESFYNTFSTYTWSWNVCQELLSAKDLRLHDASMNKSSPSNSGLSSPSDFSESDPETGRKRKRKSSRGFRQ", "length": 432 }, "evidence": [ { "id": "A0AAA9TVW9", "url": "https://omabrowser.org/oma/group/A0AAA9TVW9/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q8N7B9-1", "protein_name": "EF-hand calcium-binding domain-containing protein 3", "gene_name": "EFCAB3", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MAVSEIKPKLKLNPLTKVPISHNKRDRDLPGSLQCQLQHKEKKLSASQMAAFQDAYNFFYKDKTGCIDFHGLMCTVAKLGMNLTKHDVYNELKCADIDRDGKVNFSDFIKVLTDKNLFLKAVVPEKETCLDLAGNPGILLFEILSRLLETSALPRKSIIEIVSYFQRKFQHTGPGMLWSPYTMGYGKRTLKPDICTPPSSSMAAFANAARIAIMKEKDLFKFLEELKRCNSGSDSPYSKIPIFPLFPNVDGVVMGKPFKDMQKLEMLRIKEPLHFFEDYFFHKRDWKTQAANIKSMDPASGYSNNIFTIDQMLKKKQTCTVADATAIKQHVKRATDTYNLGIALEHRKEMLNLWQKIRGDLIGMDSRNESFYDTFSTYTWSWNVCQELLSPKDLRLYDAYVNRNSSHNSRSSSSSDTSECYTDSGRKRKRKGLKGFQQ", "length": 438 }, "evidence": [ { "id": "A0AAA9TVW9", "url": "https://omabrowser.org/oma/group/A0AAA9TVW9/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" } ], "go_annotation": { "categories": [ { "name": "Molecular Function", "total": 1, "go_terms": [ { "name": "calcium ion binding", "id": "GO:0005509", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005509", "evidence": [ { "database": "UniProtKB", "id": "A0AAA9TVW9", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TVW9" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 1010, "end_pos": 1012, "annotation": "n_glycosylation_sequon" }, { "start_pos": 1314, "end_pos": 1316, "annotation": "n_glycosylation_sequon" }, { "start_pos": 1487, "end_pos": 1489, "annotation": "n_glycosylation_sequon" }, { "start_pos": 1509, "end_pos": 1511, "annotation": "n_glycosylation_sequon" }, { "start_pos": 1723, "end_pos": 1725, "annotation": "n_glycosylation_sequon" }, { "start_pos": 1773, "end_pos": 1775, "annotation": "n_glycosylation_sequon" }, { "start_pos": 188, "end_pos": 190, "annotation": "n_glycosylation_sequon" }, { "start_pos": 262, "end_pos": 264, "annotation": "n_glycosylation_sequon" }, { "start_pos": 276, "end_pos": 278, "annotation": "n_glycosylation_sequon" }, { "start_pos": 43, "end_pos": 45, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A0AAA9TVW9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TVW9" }, { "id": "PS50222", "database": "PROSITE", "url": "https://prosite.expasy.org/PS50222" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "EF-hand", "eco_id": "ECO_0000259", "start_pos": 1297, "end_pos": 1332, "start_aa": "Leu", "end_aa": "Glu", "glycosite_overlap": [] } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" }, { "name": "homologset.oma", "label": "OMA Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [ 1704 ], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 1010, "end_pos": 1012 }, { "start_pos": 1314, "end_pos": 1316 }, { "start_pos": 1487, "end_pos": 1489 }, { "start_pos": 1509, "end_pos": 1511 }, { "start_pos": 1723, "end_pos": 1725 }, { "start_pos": 1773, "end_pos": 1775 }, { "start_pos": 188, "end_pos": 190 }, { "start_pos": 262, "end_pos": 264 }, { "start_pos": 276, "end_pos": 278 }, { "start_pos": 43, "end_pos": 45 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 1 }, { "field": "total_sites", "count": 1 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 1 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "exact_sites", "count": 1 }, { "field": "exact_o_linked_sites", "count": 1 }, { "field": "fuzzy_sites", "count": 0 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_pos", "start_aa", "end_pos", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_reported", "table_stats": [ { 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"count": 1 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 1 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "exact_sites", "count": 1 }, { "field": "exact_o_linked_sites", "count": 1 }, { "field": "fuzzy_sites", "count": 0 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_pos", "start_aa", "end_pos", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": 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"gene_names": [ { "name": "PRC1", "type": "recommended", "evidence": [ { "id": "A0AAA9TTC5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TTC5" } ] } ], "protein_names": [ { "name": "Protein regulator of cytokinesis 1", "type": "synonym", "evidence": [ { "id": "A0AAA9TTC5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TTC5/entry#names_and_taxonomy" } ] } ], "function": [], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Bos taurus", "taxid": 9913, "evidence": [ { "database": "UniProtKB", "id": "A0AAA9TTC5", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TTC5" } ], "common_name": "Bovine", "glygen_name": "Bovine", "reference_species": "Bos taurus [9913]" } ], "gene": [ { "name": "PRC1", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TTC5", "locus": { "chromosome": "21", "start_pos": 21699923, "end_pos": 21676334, "strand": "-", "evidence": [ { "database": "Ensembl Gene", "id": "ENSBTAG00000018643", "url": "https://www.ensembl.org/id/ENSBTAG00000018643" } ] } } ], "crossref": [ { "id": "A0AAA9TTC5", "url": "https://alphafold.ebi.ac.uk/entry/A0AAA9TTC5", "database": "AlphaFoldDB", "categories": [] }, { "id": "ENSBTAG00000018643", "url": "https://bgee.org/?page=gene&gene_id=ENSBTAG00000018643", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "IPR007145", "url": "https://www.ebi.ac.uk/interpro/entry/IPR007145", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "F1MRT3", "url": "https://www.orthodb.org/?gene=F1MRT3", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR19321", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR19321", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR19321:SF1", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR19321:SF1", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF03999", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF03999", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "A0A3Q1LT35", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1LT35", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A3Q1LT35-1", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1LT35-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0AAA9THV3", "url": "https://www.uniprot.org/uniprotkb/A0AAA9THV3", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0AAA9THV3-1", "url": "https://www.uniprot.org/uniprotkb/A0AAA9THV3-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0AAA9TTC5", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TTC5", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0AAA9TTC5-1", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TTC5-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0ABI0NZB3", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NZB3", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0ABI0NZB3-1", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NZB3-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "F1MRT3", "url": "https://www.uniprot.org/uniprotkb/F1MRT3", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "F1MRT3-1", "url": "https://www.uniprot.org/uniprotkb/F1MRT3-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MRRSEVLAEESIVCLQKALNHLREIWELIGIPEDQRLQRTEVVKKHIKDLLDMMIAEEESLKERLIKSIAVCQKELNTLCSELNVEPFHEEGETTILQLEKDLRTQVELRRKQKKERKQELKILQEQDQELCEILCMPHYEIDSTSVPSLEELNQFRQHVATLRETKASRREEFVNIKRQIILCMEELEHTPDTSFERDVVCEDEEAFCLSLENIATLQKLLRQLEVRKSQNEAVCEGLRAQIRELWDRLQIPAEEREAVATVMTGSKAKVRKALQLEVDRLEELKMQNMKKVIEAIRVEVAQYWDRCFYSQEQRQAFAAYYSEDYTENLLQLHDAEIVRLRNYYEVHKELFEGVQKWEESWRLFLEFERKASDPSRFTNRGGNLLKEEKQRAKLQKTLPKLEEELKARIEMWEREHSKAFVVNGQKFMEYVTEQWEMHQLEKERAKQERQLKNKKQTETEMLYGSTPRTPKRRGPTPSTPGKVRKLNTTTMSNATANSSIRPVFSGTVYRSPVSRLPPSGSKPVITSTCSGKKTPRAVKHGANKENLELNGSILSGGYPDSAPPRRNFSINSVASTYSEFAKDPSLSDSSTVGLQGCSINATASIALLSPKGLSPPHRTAFLLMKMSVCQKLGWPDSLPKR", "length": 642, "header": "tr|A0AAA9TTC5-1|A0AAA9TTC5_BOVIN Isoform 1 of Protein regulator of cytokinesis 1 OS=Bos taurus OX=9913 GN=PRC1 PE=4 SV=1 CANONICAL=A0AAA9TTC5-1" }, "isoforms": [ { "isoform_ac": "A0A3Q1LT35-1", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1LT35/entry", "sequence": { "sequence": "MRRSEVLAEESIVCLQKALNHLREIWELIGIPEDQRLQRTEVVKKHIKDLLDMMIAEEESLKERLIKSIAVCQKELNTLCSELNVEPFHEEGETTILQLEKDLRTQVELRRKQKKERKQELKILQEQDQELCEILCMPHYEIDSTSVPSLEELNQFRQHVATLRETKASRREEFVNIKRQIILCMEELEHTPDTSFERDVVCEDEEAFCLSLENIATLQKLLRQLEVRKSQNEAVCEGLRAQIRELWDRLQIPAEEREAVATVMTGSKAKVRKALQLEVDRLEELKMQNMKKVIEAIRVEVAQYWDRCFYSQEQRQAFAAYYSEDYTENLLQLHDAEIVRLRNYYEVHKELFEGVQKWEESWRLFLEFERKASDPSRFTNRGGNLLKEEKQRAKLQKTLPKLEEELKARIEMWEREHSKAFVVNGQKFMEYVTEQWEMHQLEKERAKQERLNTTTMSNATANSSIRPVFSGTVYRSPVSRLPPSGSKPVITSTCSGKKTPRAVKHGANKENLELNGSILSGGYPDSAPPRRNFSINSVASTYSEFARELSKASKSDAASRILNSTNIQS", "length": 569, "header": "tr|A0A3Q1LT35-1|A0AAA9TTC5_BOVIN Computationally mapped isoform of Protein regulator of cytokinesis 1 OS=Bos taurus OX=9913 GN=PRC1 PE=4 SV=2 CANONICAL=A0AAA9TTC5-1" }, "locus": { "chromosome": "21", "start_pos": 21698364, "end_pos": 21676450, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000076885.3", "url": "https://www.ensembl.org/id/ENSBTAT00000076885.3" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000063596.3", "url": "https://www.ensembl.org/id/ENSBTAP00000063596.3" } ] } }, { "isoform_ac": "A0AAA9THV3-1", "url": "https://www.uniprot.org/uniprotkb/A0AAA9THV3/entry", "sequence": { "sequence": "MRRSEVLAEESIVCLQKALNHLREIWELIGIPEDQRLQRTEVVKKHIKEEGETTILQLEKDLRTQVELRRKQKKERKQELKILQEQDQELCEILCMPHYEIDSTSVPSLEELNQFRQHVATLRETKASRREEFVNIKRQIILCMEELEHTPDTSFERDVVCEDEEAFCLSLENIATLQKLLRQLEVRKSQNEAVCEGLRAQIRELWDRLQIPAEEREAVATVMTGSKAKVRKALQLEVDRLEELKMQNMKKVIEAIRVEVAQYWDRCFYSQEQRQAFAAYYSEDYTENLLQLHDAEIVRLRNYYEVHKELFEGVQKWEESWRLFLEFERKASDPSRFTNRGGNLLKEEKQRAKLQKTLPKLEEELKARIEMWEREHSKAFVVNGQKFMEYVTEQWEMHQLEKERAKQERQLKNKKQTETEMLYGSTPRTPKRRGPTPSTPGKVRKLNTTTMSNATANSSIRPVFSGTVYRSPVSRLPPSGSKPVITSTCSGKKTPRAVKHGANKENLELNGSILSARTFKGFQI", "length": 524, "header": "tr|A0AAA9THV3-1|A0AAA9TTC5_BOVIN Computationally mapped isoform of Protein regulator of cytokinesis 1 OS=Bos taurus OX=9913 GN=PRC1 PE=4 SV=1 CANONICAL=A0AAA9TTC5-1" }, "locus": { "chromosome": "21", "start_pos": 21698321, "end_pos": 21676450, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000094093.2", "url": "https://www.ensembl.org/id/ENSBTAT00000094093.2" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000097841.1", "url": "https://www.ensembl.org/id/ENSBTAP00000097841.1" } ] } }, { "isoform_ac": "A0AAA9TTC5-1", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TTC5/entry", "sequence": { "sequence": "MRRSEVLAEESIVCLQKALNHLREIWELIGIPEDQRLQRTEVVKKHIKDLLDMMIAEEESLKERLIKSIAVCQKELNTLCSELNVEPFHEEGETTILQLEKDLRTQVELRRKQKKERKQELKILQEQDQELCEILCMPHYEIDSTSVPSLEELNQFRQHVATLRETKASRREEFVNIKRQIILCMEELEHTPDTSFERDVVCEDEEAFCLSLENIATLQKLLRQLEVRKSQNEAVCEGLRAQIRELWDRLQIPAEEREAVATVMTGSKAKVRKALQLEVDRLEELKMQNMKKVIEAIRVEVAQYWDRCFYSQEQRQAFAAYYSEDYTENLLQLHDAEIVRLRNYYEVHKELFEGVQKWEESWRLFLEFERKASDPSRFTNRGGNLLKEEKQRAKLQKTLPKLEEELKARIEMWEREHSKAFVVNGQKFMEYVTEQWEMHQLEKERAKQERQLKNKKQTETEMLYGSTPRTPKRRGPTPSTPGKVRKLNTTTMSNATANSSIRPVFSGTVYRSPVSRLPPSGSKPVITSTCSGKKTPRAVKHGANKENLELNGSILSGGYPDSAPPRRNFSINSVASTYSEFAKDPSLSDSSTVGLQGCSINATASIALLSPKGLSPPHRTAFLLMKMSVCQKLGWPDSLPKR", "length": 642, "header": "tr|A0AAA9TTC5-1|A0AAA9TTC5_BOVIN Isoform 1 of Protein regulator of cytokinesis 1 OS=Bos taurus OX=9913 GN=PRC1 PE=4 SV=1 CANONICAL=A0AAA9TTC5-1" }, "locus": { "chromosome": "21", "start_pos": 21698919, "end_pos": 21676450, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000130470.2", "url": "https://www.ensembl.org/id/ENSBTAT00000130470.2" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000101884.1", "url": "https://www.ensembl.org/id/ENSBTAP00000101884.1" } ] } }, { "isoform_ac": "A0ABI0NZB3-1", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NZB3/entry", "sequence": { "sequence": "MRRSEVLAEESIVCLQKALNHLREIWELIGIPEDQRLQRTEVVKKHIKDLLDMMIAEEESLKERLIKSIAVCQKELNTLCSELNVEPFHEEGETTILQLEKDLRTQVELRRKQKKERKQELKILQEQDQELCEILCMPHYEIDSTSVPSLEELNQFRQHVATLRETKASRREEFVNIKRQIILCMEELEHTPDTSFERDVVCEDEEAFCLSLENIATLQKLLRQLEVRKSQNEAVCEGLRAQIRELWDRLQIPAEEREAVATVMTGSKAKVRKALQLEVDRLEELKMQNMKKVIEAIRVEVAQYWDRCFYSQEQRQAFAAYYSEDYTENLLQLHDAEIVRLRNYYEVHKELFEGVQKWEESWRLFLEFERKASDPSRFTNRGGNLLKEEKQRAKLQKTLPKLEEELKARIEMWEREHSKAFVVNGQKFMEYVTEQWEMHQLEKERAKQERQLKNKKQTETEMLYGSTPRTPKRRGPTPSTPGKVRKLNTTTMSNATANSSIRPVFSGTVYRSPVSRLPPSGSKPVITSTCSGKKTPRAVKHGANKENLELNGSILSGGYPDSAPPRRNFSINSVASTYSEFAVIHLF", "length": 587, "header": "tr|A0ABI0NZB3-1|A0ABI0NZB3_BOVIN Computationally mapped isoform of Protein regulator of cytokinesis 1 OS=Bos taurus OX=9913 GN=PRC1 PE=4 SV=1 CANONICAL=A0AAA9TTC5-1" }, "locus": { "chromosome": "21", "start_pos": 21696216, "end_pos": 21676450, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000140165.1", "url": "https://www.ensembl.org/id/ENSBTAT00000140165.1" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000104101.1", "url": "https://www.ensembl.org/id/ENSBTAP00000104101.1" } ] } }, { "isoform_ac": "F1MRT3-1", "url": "https://www.uniprot.org/uniprotkb/F1MRT3/entry", "sequence": { "sequence": "MRRSEVLAEESIVCLQKALNHLREIWELIGIPEDQRLQRTEVVKKHIKDLLDMMIAEEESLKERLIKSIAVCQKELNTLCSELNVEPFHEEGETTILQLEKDLRTQVELRRKQKKERKQELKILQEQDQELCEILCMPHYEIDSTSVPSLEELNQFRQHVATLRETKASRREEFVNIKRQIILCMEELEHTPDTSFERDVVCEDEEAFCLSLENIATLQKLLRQLEVRKSQNEAVCEGLRAQIRELWDRLQIPAEEREAVATVMTGSKAKVRKALQLEVDRLEELKMQNMKKVIEAIRVEVAQYWDRCFYSQEQRQAFAAYYSEDYTENLLQLHDAEIVRLRNYYEVHKELFEGVQKWEESWRLFLEFERKASDPSRFTNRGGNLLKEEKQRAKLQKTLPKLEEELKARIEMWEREHSKAFVVNGQKFMEYVTEQWEMHQLEKERAKQERQLKNKKQTETEMLYGSTPRTPKRRGPTPSTPGKVRKLNTTTMSNATANSSIRPVFSGTVYRSPVSRLPPSGSKPVITSTCSGKKTPRAVKHGANKENLELNGSILSGGYPDSAPPRRNFSINSVASTYSEFAGCSINATASIALLSPKGLSPPHRTAFLLMKMSVCQKLGWPDSLPKR", "length": 628, "header": "tr|F1MRT3-1|A0AAA9TTC5_BOVIN Computationally mapped isoform of Protein regulator of cytokinesis 1 OS=Bos taurus OX=9913 GN=PRC1 PE=4 SV=4 CANONICAL=A0AAA9TTC5-1" }, "locus": { "chromosome": "21", "start_pos": 21698919, "end_pos": 21676450, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000024808.8", "url": "https://www.ensembl.org/id/ENSBTAT00000024808.8" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000024808.7", "url": "https://www.ensembl.org/id/ENSBTAP00000024808.7" } ] } } ], "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "other", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 477, "start_aa": "Thr", "end_pos": 477, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr477", "evidence": [ { "id": "", "database": "GlyGen", "url": "https://data.glygen.org/" } ], "filter_code": "000000000000000010000.00000000001000.0.01000" }, { "glytoucan_ac": "", "type": "O-linked", "subtype": "other", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 480, "start_aa": "Thr", "end_pos": 480, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr480", "evidence": [ { "id": "", "database": "GlyGen", "url": "https://data.glygen.org/" } ], "filter_code": "000000000000000010000.00000000001000.0.01000" } ], "phosphorylation": [], "glycation": [], "keywords": [ "glycoprotein", "glycoprotein_predicted" ], "publication": [], "pathway": [], "orthologs": [], "go_annotation": { "categories": [ { "name": "Molecular Function", "total": 3, "go_terms": [ { "name": "microtubule binding", "id": "GO:0008017", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008017", "evidence": [ { "database": "UniProtKB", "id": "A0AAA9TTC5", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TTC5" } ], "pmid": "" }, { "name": "protein kinase binding", "id": "GO:0019901", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0019901", "evidence": [ { "database": "UniProtKB", "id": "A0AAA9TTC5", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TTC5" } ], "pmid": "" }, { "name": "kinesin binding", "id": "GO:0019894", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0019894", "evidence": [ { "database": "UniProtKB", "id": "A0AAA9TTC5", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TTC5" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 3, "go_terms": [ { "name": "microtubule cytoskeleton organization", "id": "GO:0000226", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000226", "evidence": [ { "database": "UniProtKB", "id": "A0AAA9TTC5", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TTC5" } ], "pmid": "" }, { "name": "positive regulation of cell population proliferation", "id": "GO:0008284", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008284", "evidence": [ { "database": "UniProtKB", "id": "A0AAA9TTC5", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TTC5" } ], "pmid": "" }, { "name": "regulation of cytokinesis", "id": "GO:0032465", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0032465", "evidence": [ { "database": "UniProtKB", "id": "A0AAA9TTC5", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TTC5" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 4, "go_terms": [ { "name": "nucleoplasm", "id": "GO:0005654", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005654", "evidence": [ { "database": "UniProtKB", "id": "A0AAA9TTC5", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TTC5" } ], "pmid": "" }, { "name": "spindle", "id": "GO:0005819", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005819", "evidence": [ { "database": "UniProtKB", "id": "A0AAA9TTC5", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TTC5" } ], "pmid": "" }, { "name": "midbody", "id": "GO:0030496", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030496", "evidence": [ { "database": "UniProtKB", "id": "A0AAA9TTC5", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TTC5" } ], "pmid": "" }, { "name": "contractile ring", "id": "GO:0070938", "url": 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"length": 1247, "header": "tr|A0AAA9TVS1-1|A0AAA9TVS1_BOVIN Isoform 1 of PTPRF interacting protein alpha 2 OS=Bos taurus OX=9913 GN=PPFIA2 PE=3 SV=1 CANONICAL=A0AAA9TVS1-1" }, "isoforms": [ { "isoform_ac": "A0A3Q1LTJ4-1", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1LTJ4/entry", "sequence": { "sequence": 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"length": 1222, "header": "tr|A0A3Q1LTJ4-1|A0AAA9TVS1_BOVIN Computationally mapped isoform of PTPRF interacting protein alpha 2 OS=Bos taurus OX=9913 GN=PPFIA2 PE=3 SV=2 CANONICAL=A0AAA9TVS1-1" }, "locus": { "chromosome": "5", "start_pos": 11345480, "end_pos": 10851400, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000067667.2", "url": "https://www.ensembl.org/id/ENSBTAT00000067667.2" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000058450.2", "url": "https://www.ensembl.org/id/ENSBTAP00000058450.2" } ] } }, { "isoform_ac": "A0A3Q1M5L6-1", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1M5L6/entry", "sequence": { "sequence": "MMCEVMPTINEDTPMSQRGSQSSGSDSDSHFEQLMVNMLDERDRLLDTLRETQESLSLAQQRLQDVIYDRDSLQRQLNSALPQDIESLTGGLTGSKGADPPEFAALTKELNACREQLLEKEEEISELKAERNNTRLLLEHLECLVSRHERSLRMTVVKRQAQSPSGVSSEVEVLKALKSLFEHHKALDEKVRERLRVSLERVSALEEELAAANQEIVALREQNVHIQRKMVSSEGSTESEHLEGMEPGQKVHEKRLSNGSIDSTDETSQIVELQELLEKQNYEMAQMKERLAALSSRVGEVEQEAETARKDLIKTEEMNTKYQRDIREAMAQKEDMEERITTLEKRYLSAQRESTSIHDMNDKLENELANKEAILRQMEEKNRQLQERLELAEQKLQQTMRKAETLPEVEAELAQRIAALTKAEERHGNIEERMRHLEGQLEEKNQELQRARQREKMNEEHNKRLSDTVDRLLTESNERLQLHLKERMAALEEKNVLIQESETFRKNLEESLHDKERLAEEIEKLRSELDQLKMRTGSLIEPTIPRTHLDTSAELRYSVGSLVDSQSDYRTTKVIRRPRRGRMGVRRDEAKVKSLGDHEWNRTQQIGVLSSHPFESDTEMSDIDDDDRETIFSSMDLLSPSGHSDAQTLAMMLQEQLDAINKEIRLIQEEKESTELRAEEIENRVASVSLEGLNLARVHPGTSITASVTASSLASSSPPSGHSTPKLTPRSPAREMDRMGVMTLPSDLRKHRRKIAVVEEDGREDKATIKCETSPPPTPRAIRMTHTLPSSYHNDARSSLSASLEPESLGLGSANSSQDSLHKAPKKKGIKSSIGRLFGKKEKARLGQLRGFMETEAAAQESLGLGKLGTQAEKDRRLKKKHELLEEARRKGLPFAQWDGPTVVAWLELWLGMPAWYVAACRANVKSGAIMSALSDTEIQREIGISNPLHRLKLRLAIQEMVSLTSPSAPPTSRTKESEEGSWAQCPVFLQTLAYGDMNHEWIGNEWLPSLGLPQYRSYFMECLVDARMLDHLTKKDLRVHLKMVDSFHRTSLQYGIMCLKRLNYDRKELERRREASQHEIKDVLVWSNDRVIRWIQAIGLREYANNILESGVHGSLIALDENFDYSSLALLLQIPTQNTQARQILEREYNNLLALGTERRLDESEDKNFRRGSTWRRQFPPREVHGISMMPGSSETLPAGFRLTTTSGQSRKMTTDVASSRLQRLDNSTVRTYSC", "length": 1236, "header": "tr|A0A3Q1M5L6-1|A0A3Q1M5L6_BOVIN Computationally mapped isoform of PTPRF interacting protein alpha 2 OS=Bos taurus OX=9913 GN=PPFIA2 PE=3 SV=2 CANONICAL=A0AAA9TVS1-1" }, "locus": { "chromosome": "5", "start_pos": 11345480, "end_pos": 10851400, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000081984.2", "url": "https://www.ensembl.org/id/ENSBTAT00000081984.2" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000065599.2", "url": "https://www.ensembl.org/id/ENSBTAP00000065599.2" } ] } }, { "isoform_ac": "A0A3Q1NMT2-1", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1NMT2/entry", "sequence": { "sequence": "MMCEVMPTINEDTPMSQRGSQSSGSDSDSHFEQLMVNMLDERDRLLDTLRETQESLSLAQQRLQDVIYDRDSLQRQLNSALPQEFAALTKELNACREQLLEKEEEISELKAERNNTRLLLEHLECLVSRHERSLRMTVVKRQAQSPSGVSSEVEVLKALKSLFEHHKALDEKVRERLRVSLERVSALEEELAAANQEIVALREQNVHIQRKMVSSEGSTESEHLEGMEPGQKVHEKRLSNGSIDSTDETSQIVELQELLEKQNYEMAQMKERLAALSSRVGEVEQEAETARKDLIKTEEMNTKYQRDIREAMAQKEDMEERITTLEKRYLSAQRESTSIHDMNDKLENELANKEAILRQMEEKNRQLQERLELAEQKLQQTMRKAETLPEVEAELAQRIAALTKAEERHGNIEERMRHLEGQLEEKNQELQRARQREKMNEEHNKRLSDTVDRLLTESNERLQLHLKERMAALEEKNVLIQESETFRKNLEESLHDKERLAEEIEKLRSELDQLKMRTGSLIEPTIPRTHLDTSAELRYSVGSLVDSQSDYRTTKVIRRPRRGRMGVRRDEAKVKSLGDHEWNRTQQIGVLSSHPFESDTEMSDIDDDDRETIFSSMDLLSPSGHSDAQTLAMMLQEQLDAINKEIRLIQEEKESTELRAEEIENRVASVSLEGLNLARVHPGTSITASVTASSLASSSPPSGHSTPKLTPRSPAREMDRMGVMTLPSDLRKHRRKIAVVEEDGREDKATIKCETSPPPTPRAIRMTHTLPSSYHNDARSSLSASLEPESLGLGSANSSQDSLHKAPKKKGIKSSIGRLFGKKEKARLGQLRGFMETEAAAQESLGLGKLGTQAEKDRRLKKNTSGHELLEEARRKGLPFAQWDGPTVVAWLELWLGMPAWYVAACRANVKSGAIMSALSDTEIQREIGISNPLHRLKLRLAIQEMVSLTSPSAPPTSRTPSGNVWVTHEEMENLTAPAKTKESEEGSWAQCPVFLQTLAYGDMNHEWIGNEWLPSLGLPQYRSYFMECLVDARMLDHLTKKDLRVHLKMVDSFHRTSLQYGIMCLKRLNYDRKELERRREASQHEIKDVLVWSNDRVIRWIQAIGLREYANNILESGVHGSLIALDENFDYSSLALLLQIPTQNTQARQILEREYNNLLALGTERRLDESEDKNFRRGSTWRRQFPPREVHGISMMPGSSETLPAGFRLTTTSGQSRKMTTDDVVFSVYST", "length": 1232, "header": "tr|A0A3Q1NMT2-1|A0AAA9TVS1_BOVIN Computationally mapped isoform of PTPRF interacting protein alpha 2 OS=Bos taurus OX=9913 GN=PPFIA2 PE=3 SV=2 CANONICAL=A0AAA9TVS1-1" }, "locus": { "chromosome": "5", "start_pos": 11345480, "end_pos": 10849061, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000073740.2", "url": "https://www.ensembl.org/id/ENSBTAT00000073740.2" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000073953.2", "url": "https://www.ensembl.org/id/ENSBTAP00000073953.2" } ] } }, { "isoform_ac": "A0AAA9T3A2-1", "url": "https://www.uniprot.org/uniprotkb/A0AAA9T3A2/entry", "sequence": { "sequence": "MMCEVMPTINEDTPMSQRGSQSSGSDSDSHFEQLMVNMLDERDRLLDTLRETQESLSLAQQRLQDVIYDRDSLQRQLNSALPQDIESLTGGLTGSKGADPPEFAALTKELNACREQLLEKEEEISELKAERNNTRLLLEHLECLVSRHERSLRMTVVKRQAQSPSGVSSEVEVLKALKSLFEHHKALDEKVRERLRVSLERVSALEEELAAANQEIVALREQNVHIQRKMVSSEGSTESEHLEGMEPGQKVHEKRLSNGSIDSTDETSQIVELQELLEKQNYEMAQMKERLAALSSRVGEVEQEAETARKDLIKTEEMNTKYQRDIREAMAQKEDMEERITTLEKRYLSAQRESTSIHDMNDKLENELANKEAILRQMEEKNRQLQERLELAEQKLQQTMRKAETLPEVEAELAQRIAALTKAEERHGNIEERMRHLEGQLEEKNQELQRARQREKMNEEHNKRLSDTVDRLLTESNERLQLHLKERMAALEEKNVLIQESETFRKNLEESLHDKERLAEEIEKLRSELDQLKMRTGSLIEPTIPRTHLDTSAELRYSVGSLVDSQSDYRTTKVIRRPRRGRMGVRRDEAKVKSLGDHEWNRTQQIGVLSSHPFESDTEMSDIDDDDRETIFSSMDLLSPSGHSDAQTLAMMLQEQLDAINKEIRLIQEEKESTELRAEEIENRVASVSLEGLNLARVHPGTSITASVTASSLASSSPPSGHSTPKLTPRSPAREMDRMGVMTLPSDLRKHRRKIAVVEEDGREDKATIKCETSPPPTPRAIRMTHTLPSSYHNDARSSLSASLEPESLGLGSANSSQDSLHKAPKKKGIKSSIGRLFGKKEKARLGQLRGFMETEAAAQESLGLGKLGTQAEKDRRLKKKHELLEEARRKGLPFAQWDGPTVVAWLELWLGMPAWYVAACRANVKSGAIMSALSDTEIQREIGISNPLHRLKLRLAIQEMVSLTSPSAPPTSRTCPVFLQTLAYGDMNHEWIGNEWLPSLGLPQYRSYFMECLVDARMLDHLTKKDLRVHLKMVDSFHRTSLQYGIMCLKRLNYDRKELERRREASQHEIKDVLVWSNDRVIRWIQAIGLREYANNILESGVHGSLIALDENFDYSSLALLLQIPTQNTQARQILEREYNNLLALGTERRLDESEDKNFRRGSTWRRQFPPREVHGISMMPGSSETLPAGFRLTTTSGQSRKMTTDDVVFSVYST", "length": 1216, "header": "tr|A0AAA9T3A2-1|A0AAA9TVS1_BOVIN Computationally mapped isoform of PTPRF interacting protein alpha 2 OS=Bos taurus OX=9913 GN=PPFIA2 PE=3 SV=1 CANONICAL=A0AAA9TVS1-1" }, "locus": { "chromosome": "5", "start_pos": 11345480, "end_pos": 10849061, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000126642.1", "url": "https://www.ensembl.org/id/ENSBTAT00000126642.1" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000091107.1", "url": "https://www.ensembl.org/id/ENSBTAP00000091107.1" } ] } }, { "isoform_ac": "A0AAA9TQL3-1", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TQL3/entry", "sequence": { "sequence": "MMCEVMPTINEDTPMSQRGSQSSGSDSDSHFEQLMVNMLDERDRLLDTLRETQESLSLAQQRLQDVIYDRDSLQRQLNSALPQDIESLTGGLTGSKGADPPEFAALTKELNACREQLLEKEEEISELKAERNNTRLLLEHLECLVSRHERSLRMTVVKRQAQSPSGVSSEVEVLKALKSLFEHHKALDEKVRERLRVSLERVSALEEELAAANQEIVALREQNVHIQRKMVSSEGSTESEHLEGMEPGQKVHEKRLSNGSIDSTDETSQIVELQELLEKQNYEMAQMKERLAALSSRVGEVEQEAETARKDLIKTEEMNTKYQRDIREAMAQKEDMEERITTLEKRYLSAQRESTSIHDMNDKLENELANKEAILRQMEEKNRQLQERLELAEQKLQQTMRKAETLPEVEAELAQRIAALTKAEERHGNIEERMRHLEGQLEEKNQELQRARQREKMNEEHNKRLSDTVDRLLTESNERLQLHLKERMAALEEKNVLIQESETFRKNLEESLHDKERLAEEIEKLRSELDQLKMRTGSLIEPTIPRTHLDTSAELRYSVGSLVDSQSDYRTTKVIRRPRRGRMGVRRDEAKVKSLGDHEWNRTQQIGVLSSHPFESDTEMSDIDDDDRETIFSSMDLLSPSGHSDAQTLAMMLQEQLDAINKEIRLIQEEKESTELRAEEIENRVASVSLEGLNLARVHPGTSITASVTASSLASSSPPSGHSTPKLTPRSPAREMDRMGVMTLPSDLRKHRRKIAVVEEDGREDKATIKCETSPPPTPRAIRMTHTLPSSYHNDARSSLSASLEPESLGLGSANSSQDSLHKAPKKKGIKSSIGRLFGKKEKARLGQLRGFMETEAAAQESLGLGKLGTQAEKDRRLKKKHELLEEARRKGLPFAQWDGPTVVAWLELWLGMPAWYVAACRANVKSGAIMSALSDTEIQREIGISNPLHRLKLRLAIQEMVSLTSPSAPPTSRTPSGNVWVTHEEMENLTAPAKTCPVFLQTLAYGDMNHEWIGNEWLPSLGLPQYRSYFMECLVDARMLDHLTKKDLRVHLKMVDSFHRTSLQYGIMCLKRLNYDRKELERRREASQHEIKDVLVWSNDRVIRWIQAIGLREYANNILESGVHGSLIALDENFDYSSLALLLQIPTQNTQARQILEREYNNLLALGTERRLDESEDKNFRRGSTWRRQFPPREVHGISMMPGSSETLPAGFRLTTTSGQSRKMTTDDVVFSVYST", "length": 1237, "header": "tr|A0AAA9TQL3-1|A0AAA9TVS1_BOVIN Computationally mapped isoform of PTPRF interacting protein alpha 2 OS=Bos taurus OX=9913 GN=PPFIA2 PE=3 SV=1 CANONICAL=A0AAA9TVS1-1" }, "locus": { "chromosome": "5", "start_pos": 11345480, "end_pos": 10849061, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000130774.1", "url": "https://www.ensembl.org/id/ENSBTAT00000130774.1" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000100876.1", "url": "https://www.ensembl.org/id/ENSBTAP00000100876.1" } ] } }, { "isoform_ac": "A0AAA9TVS1-1", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TVS1/entry", "sequence": { "sequence": "MMCEVMPTINEDTPMSQRGSQSSGSDSDSHFEQLMVNMLDERDRLLDTLRETQESLSLAQQRLQDVIYDRDSLQRQLNSALPQDIESLTGGLTGSKGADPPEFAALTKELNACREQLLEKEEEISELKAERNNTRLLLEHLECLVSRHERSLRMTVVKRQAQSPSGVSSEVEVLKALKSLFEHHKALDEKVRERLRVSLERVSALEEELAAANQEIVALREQNVHIQRKMVSSEGSTESEHLEGMEPGQKVHEKRLSNGSIDSTDETSQIVELQELLEKQNYEMAQMKERLAALSSRVGEVEQEAETARKDLIKTEEMNTKYQRDIREAMAQKEDMEERITTLEKRYLSAQRESTSIHDMNDKLENELANKEAILRQMEEKNRQLQERLELAEQKLQQTMRKAETLPEVEAELAQRIAALTKAEERHGNIEERMRHLEGQLEEKNQELQRARQREKMNEEHNKRLSDTVDRLLTESNERLQLHLKERMAALEEKNVLIQESETFRKNLEESLHDKERLAEEIEKLRSELDQLKMRTGSLIEPTIPRTHLDTSAELRYSVGSLVDSQSDYRTTKVIRRPRRGRMGVRRDEAKVKSLGDHEWNRTQQIGVLSSHPFESDTEMSDIDDDDRETIFSSMDLLSPSGHSDAQTLAMMLQEQLDAINKEIRLIQEEKESTELRAEEIENRVASVSLEGLNLARVHPGTSITASVTASSLASSSPPSGHSTPKLTPRSPAREMDRMGVMTLPSDLRKHRRKIAVVEEDGREDKATIKCETSPPPTPRAIRMTHTLPSSYHNDARSSLSASLEPESLGLGSANSSQDSLHKAPKKKGIKSSIGRLFGKKEKARLGQLRGFMETEAAAQESLGLGKLGTQAEKDRRLKKKHELLEEARRKGLPFAQWDGPTVVAWLELWLGMPAWYVAACRANVKSGAIMSALSDTEIQREIGISNPLHRLKLRLAIQEMVSLTSPSAPPTSRTPSGNVWVTHEEMENLTAPAKTKESEEGSWAQCPVFLQTLAYGDMNHEWIGNEWLPSLGLPQYRSYFMECLVDARMLDHLTKKDLRVHLKMVDSFHRTSLQYGIMCLKRLNYDRKELERRREASQHEIKDVLVWSNDRVIRWIQAIGLREYANNILESGVHGSLIALDENFDYSSLALLLQIPTQNTQARQILEREYNNLLALGTERRLDESEDKNFRRGSTWRRQFPPREVHGISMMPGSSETLPAGFRLTTTSGQSRKMTTDDVVFSVYST", "length": 1247, "header": "tr|A0AAA9TVS1-1|A0AAA9TVS1_BOVIN Isoform 1 of PTPRF interacting protein alpha 2 OS=Bos taurus OX=9913 GN=PPFIA2 PE=3 SV=1 CANONICAL=A0AAA9TVS1-1" }, "locus": { "chromosome": "5", "start_pos": 11345480, "end_pos": 10849061, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000128499.1", "url": "https://www.ensembl.org/id/ENSBTAT00000128499.1" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000100691.1", "url": "https://www.ensembl.org/id/ENSBTAP00000100691.1" } ] } }, { "isoform_ac": "E1BND7-1", "url": "https://www.uniprot.org/uniprotkb/E1BND7/entry", "sequence": { "sequence": "MIFSDMNTVSGSPKVHPPNGTRFYTFQEFAALTKELNACREQLLEKEEEISELKAERNNTRLLLEHLECLVSRHERSLRMTVVKRQAQSPSGVSSEVEVLKALKSLFEHHKALDEKVRERLRVSLERVSALEEELAAANQEIVALREQNVHIQRKMVSSEGSTESEHLEGMEPGQKVHEKRLSNGSIDSTDETSQIVELQELLEKQNYEMAQMKERLAALSSRVGEVEQEAETARKDLIKTEEMNTKYQRDIREAMAQKEDMEERITTLEKRYLSAQRESTSIHDMNDKLENELANKEAILRQMEEKNRQLQERLELAEQKLQQTMRKAETLPEVEAELAQRIAALTKAEERHGNIEERMRHLEGQLEEKNQELQRARQREKMNEEHNKRLSDTVDRLLTESNERLQLHLKERMAALEEKNVLIQESETFRKNLEESLHDKERLAEEIEKLRSELDQLKMRTGSLIEPTIPRTHLDTSAELRYSVGSLVDSQSDYRTTKVIRRPRRGRMGVRRDEAKVKSLGDHEWNRTQQIGVLSSHPFESDTEMSDIDDDDRETIFSSMDLLSPSGHSDAQTLAMMLQEQLDAINKEIRLIQEEKESTELRAEEIENRVASVSLEGLNLARVHPGTSITASVTASSLASSSPPSGHSTPKLTPRSPAREMDRMGVMTLPSDLRKHRRKIAVVEEDGREDKATIKCETSPPPTPRAIRMTHTLPSSYHNDARSSLSASLEPESLGLGSANSSQDSLHKAPKKKGIKSSIGRLFGKKEKARLGQLRGFMETEAAAQESLGLGKLGTQAEKDRRLKKKHELLEEARRKGLPFAQWDGPTVVAWLELWLGMPAWYVAACRANVKSGAIMSALSDTEIQREIGISNPLHRLKLRLAIQEMVSLTSPSAPPTSRTKESEEGSWAQTLAYGDMNHEWIGNEWLPSLGLPQYRSYFMECLVDARMLDHLTKKDLRVHLKMVDSFHRTSLQYGIMCLKRLNYDRKELERRREASQHEIKDVLVWSNDRVIRWIQAIGLREYANNILESGVHGSLIALDENFDYSSLALLLQIPTQNTQARQILEREYNNLLALGTERRLDESEDKNFRRGSTWRRQFPPREVHGISMMPGSSETLPAGFRLTTTSGQSRKMTTDVASSRLQRLDNSTVRTYSC", "length": 1156, "header": "tr|E1BND7-1|A0AAA9TVS1_BOVIN Computationally mapped isoform of PTPRF interacting protein alpha 2 OS=Bos taurus OX=9913 GN=PPFIA2 PE=3 SV=4 CANONICAL=A0AAA9TVS1-1" }, "locus": { "chromosome": "5", "start_pos": 11183184, "end_pos": 10851400, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000061316.4", "url": "https://www.ensembl.org/id/ENSBTAT00000061316.4" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000053568.4", "url": "https://www.ensembl.org/id/ENSBTAP00000053568.4" } ] } } ], "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "other", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 778, "start_aa": "Thr", "end_pos": 778, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr778", "evidence": [ { "id": "", "database": "GlyGen", "url": "https://data.glygen.org/" } ], "filter_code": "000000000000000010000.00000000001000.0.01000" } ], "phosphorylation": [], "glycation": [], "keywords": [ "glycoprotein", "glycoprotein_predicted" ], "publication": [], "pathway": [ { "id": "R-BTA-181429", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-BTA-181429", "resource": "Reactome", "description": "Serotonin Neurotransmitter Release Cycle" }, { "id": "R-BTA-181430", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-BTA-181430", "resource": "Reactome", "description": "Norepinephrine Neurotransmitter Release Cycle" }, { "id": "R-BTA-210500", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-BTA-210500", "resource": "Reactome", "description": "Glutamate Neurotransmitter Release Cycle" }, { "id": "R-BTA-212676", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-BTA-212676", "resource": "Reactome", "description": "Dopamine Neurotransmitter Release Cycle" }, { "id": "R-BTA-264642", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-BTA-264642", "resource": "Reactome", "description": "Acetylcholine Neurotransmitter Release Cycle" }, { "id": "R-BTA-388844", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-BTA-388844", "resource": "Reactome", "description": "Receptor-type tyrosine-protein phosphatases" } ], "orthologs": [], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 4, "go_terms": [ { "name": "cytoplasm", "id": "GO:0005737", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005737", "evidence": [ { "database": "UniProtKB", "id": "A0AAA9TVS1", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TVS1" } ], "pmid": "" }, { "name": "axon", "id": "GO:0030424", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030424", "evidence": [ { "database": "UniProtKB", "id": "A0AAA9TVS1", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TVS1" } ], "pmid": "" }, { "name": "dendritic spine", "id": "GO:0043197", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0043197", "evidence": [ { "database": "UniProtKB", "id": "A0AAA9TVS1", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TVS1" } ], "pmid": "" }, { "name": "presynaptic active zone", "id": "GO:0048786", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0048786", "evidence": [ { "database": "UniProtKB", "id": "A0AAA9TVS1", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TVS1" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 4, "go_terms": [ { "name": "regulation of dendritic spine development", "id": "GO:0060998", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0060998", "evidence": [ { "database": "UniProtKB", "id": "A0AAA9TVS1", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TVS1" } ], "pmid": "" }, { "name": "regulation of dendritic spine morphogenesis", "id": "GO:0061001", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0061001", "evidence": [ { "database": "UniProtKB", "id": "A0AAA9TVS1", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TVS1" } ], "pmid": "" }, { "name": "dense core granule cytoskeletal transport", "id": "GO:0099519", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0099519", "evidence": [ { "database": "UniProtKB", "id": "A0AAA9TVS1", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TVS1" } ], "pmid": "" }, { "name": "synapse organization", "id": "GO:0050808", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0050808", "evidence": [ { "database": "UniProtKB", "id": "A0AAA9TVS1", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TVS1" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 132, "end_pos": 134, "annotation": "n_glycosylation_sequon" }, { "start_pos": 258, "end_pos": 260, "annotation": "n_glycosylation_sequon" }, { "start_pos": 601, "end_pos": 603, "annotation": "n_glycosylation_sequon" }, { "start_pos": 815, "end_pos": 817, "annotation": "n_glycosylation_sequon" }, { "start_pos": 989, "end_pos": 991, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A0AAA9TVS1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TVS1" }, { "id": "PS50105", "database": "PROSITE", "url": "https://prosite.expasy.org/PS50105" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "SAM", "eco_id": "ECO_0000259", "start_pos": 898, "end_pos": 964, "start_aa": "Trp", "end_aa": "Leu", "glycosite_overlap": [] } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [ 778 ], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 132, "end_pos": 134 }, { "start_pos": 258, "end_pos": 260 }, { "start_pos": 601, "end_pos": 603 }, { "start_pos": 815, "end_pos": 817 }, { "start_pos": 989, "end_pos": 991 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 1 }, { "field": "total_sites", "count": 1 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 1 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "exact_sites", "count": 1 }, { "field": "exact_o_linked_sites", "count": 1 }, { "field": "fuzzy_sites", "count": 0 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_pos", "start_aa", "end_pos", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", 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] } ], "sequence": { "sequence": "MERLKNQAGRQLSLLKVKKKWLLPASCSFFFVLSALMTGCFLWQYYLPKLKSGSLGPEVTSAPVRMCPQHPEPVPLAHPLPVLKEALEKVGRILRQALSAPGLAAMSAVVIHNDTVLWTGNFGKKNGSDPASGPPNEYTMYRISSVSKIFPVLMLYRLWEEGIVASLDDPLERYASAFTINNPLGMASASQQRSLVDGLEEVGPAPRPSPVTLRRMASQLSGLPRRLRSTSLLWRGSTQEALSLLKDDVLVADPGTRCHYSTLAFSLLAHVLAAHTVQGDYQRWILEKVLEPLGMADTGFDLTPPVRARLAVGFYGSGRLAPLYDLGWYRPSGQMYSTTADLAKLAMVLLGGGPQRLLRPDASKTLLAPLLACPGAYFANETGTPWEFHAQRGYRVVRKDGELDGYAATFSLVPPLRLGLTLLLAGPRPPGPDLVAQAYDVLLPAMERALRGAELSPAPPPSTRPFTGYFTFSNLTFYDVRPGPAGELRLRQFGPRVEALVPAAFRTLTLRHVRGRVFQLHVAREFPCALPLGDSWLSLEAQHGQLVNFYPLDRHGLSPGFDVPGLNTYRVLRLSHKPVFKTQ", "length": 583, "header": "tr|A0AAA9TSE3-1|A0AAA9TSE3_BOVIN Isoform 1 of Lactamase beta like 1 OS=Bos taurus OX=9913 GN=LACTBL1 PE=3 SV=1 CANONICAL=A0AAA9TSE3-1" }, "isoforms": [ { "isoform_ac": "A0A3Q1LTX6-1", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1LTX6/entry", "sequence": { "sequence": 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"locus": { "chromosome": "2", "start_pos": 129878000, "end_pos": 129861777, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000127532.1", "url": "https://www.ensembl.org/id/ENSBTAT00000127532.1" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000101522.1", "url": "https://www.ensembl.org/id/ENSBTAP00000101522.1" } ] } }, { "isoform_ac": "F1N5C1-1", "url": "https://www.uniprot.org/uniprotkb/F1N5C1/entry", "sequence": { "sequence": "MPSRGNRRGTGMEAGRQLSLLKVKKKWLLPASCSFFFVLSALMTGCFLWQYYLPKLKSGSLGPEVTSAPVRMCPQHPEPVPLAHPLPVLKEALEKVGRILRQALSAPGLAAMSAVVIHNDTVLWTGNFGKKNGSDPASGPPNEYTMYRISSVSKIFPVLMLYRLWEEGIVASLDDPLERYASAFTINNPLGMASASQQRSLVDGLEEVGPAPRPSPVTLRRMASQLSGLPRRLRSTSLLWRGSTQEALSLLKDDVLVADPGTRCHYSTLAFSLLAHVLAAHTVQGDYQRWILEKVLEPLGMADTGFDLTPPVRARLAVGFYGSGRLAPLYDLGWYRPSGQMYSTTADLAKLAMVLLGGGPQRLLRPDASKTLLAPLLACPGAYFANETGTPWEFHAQRGYRVVRKDGELDGYAATFSLVPPLRLGLTLLLAGPRPPGPDLVAQAYDVLLPAMERALRGAELSPAPPPSTRPFTGYFTFSNLTFYDVRPGPAGELRLRQFGPRVEALVPAAFRTLTLRHVRGRVFQLHVAREFPCALPLGDSWLSLEAQHGQLVNFYPLDRHGLSPGFDVPGLNTYRVLRLSHKPVFKTQ", "length": 589, "header": "tr|F1N5C1-1|F1N5C1_BOVIN Computationally mapped isoform of Lactamase beta like 1 OS=Bos taurus OX=9913 GN=LACTBL1 PE=3 SV=4 CANONICAL=A0AAA9TSE3-1" }, "locus": { "chromosome": "2", "start_pos": 129878000, "end_pos": 129863000, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000042939.4", "url": "https://www.ensembl.org/id/ENSBTAT00000042939.4" }, 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"url": "https://www.ncbi.nlm.nih.gov/protein/XP_005205243" } ] } ], "function": [], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Bos taurus", "taxid": 9913, "evidence": [ { "database": "UniProtKB", "id": "A0AAA9TV31", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TV31" } ], "common_name": "Bovine", "glygen_name": "Bovine", "reference_species": "Bos taurus [9913]" } ], "gene": [ { "name": "ICA1", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TV31", "locus": { "chromosome": "4", "start_pos": 16191441, "end_pos": 16355628, "strand": "+", "evidence": [ { "database": "Ensembl Gene", "id": "ENSBTAG00000000799", "url": "https://www.ensembl.org/id/ENSBTAG00000000799" } ] } } ], "crossref": [ { "id": "A0AAA9TV31", "url": "https://alphafold.ebi.ac.uk/entry/A0AAA9TV31", "database": "AlphaFoldDB", "categories": [] }, { "id": "ENSBTAG00000000799", "url": "https://bgee.org/?page=gene&gene_id=ENSBTAG00000000799", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "cd07661", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd07661", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "535346", "url": "https://www.ncbi.nlm.nih.gov/gene/535346", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR006723", "url": "https://www.ebi.ac.uk/interpro/entry/IPR006723", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR010504", "url": "https://www.ebi.ac.uk/interpro/entry/IPR010504", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR024114", "url": "https://www.ebi.ac.uk/interpro/entry/IPR024114", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR027267", "url": "https://www.ebi.ac.uk/interpro/entry/IPR027267", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "A0A3Q1M1Y0", "url": "https://www.orthodb.org/?gene=A0A3Q1M1Y0", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A3Q1MG19", "url": "https://www.orthodb.org/?gene=A0A3Q1MG19", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A3Q1N2K1", "url": "https://www.orthodb.org/?gene=A0A3Q1N2K1", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "F1MW75", "url": "https://www.orthodb.org/?gene=F1MW75", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR10164", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR10164", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR10164:SF3", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR10164:SF3", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF04629", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF04629", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF06456", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF06456", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "XP_005205243", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_005205243", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A3Q1M1Y0", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1M1Y0", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A3Q1M1Y0-1", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1M1Y0-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A3Q1MG19", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1MG19", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A3Q1MG19-1", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1MG19-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A3Q1N2K1", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1N2K1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A3Q1N2K1-1", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1N2K1-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0AAA9TV31", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TV31", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0AAA9TV31-1", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TV31-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "F1MW75", "url": "https://www.uniprot.org/uniprotkb/F1MW75", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "F1MW75-1", "url": "https://www.uniprot.org/uniprotkb/F1MW75-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MSGHKCSYPWDLHNRYPQDKSVVNKMQQKYWETKQAFIKATGKKEDEHVVASDADLDAKLELFHSIQRTCLDLSKAIVLYQKRICFLSQEENELGKFLRSQGFQDKTRAGKMMQATGKALCFSSQQRLALRNPLCRFHQEVETFRHRAISDTWLTVNRMEQCRTEYRGALLWMKDVSQELDPDLCKQMEKFRKVQTQVRLAKKSFDKLKMDVCQKVDLLGASRCNLLSHMLATYQTTLLHFWEKTSHTMAAIHESFRGYQPYEFTTLKSLQDPMRKLVEKEEKKRIAQQESAEAVAEEPSQLISLEDENQHKESSSFKTEDRKSVLSALDKSCTHNACADELLDMKPEEGACLGPMAGTPEPEGADKDDLLLLSEIFNASSLEEGEFSKEWAAVFGDGRLKEPMPTAAPGELDPRPQAGSGFLPSQLLDQNIKDLQASLEGWSESSVSPSPPWPAPKASSANVNYPAVKEPAKASSDLTAWFSLFADLDPLSNPDAIGKTDKEHELLNA", "length": 509, "header": "tr|A0AAA9TV31-1|A0AAA9TV31_BOVIN Isoform 1 of Islet cell autoantigen 1 OS=Bos taurus OX=9913 GN=ICA1 PE=4 SV=1 CANONICAL=A0AAA9TV31-1" }, "isoforms": [ { "isoform_ac": "A0A3Q1M1Y0-1", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1M1Y0/entry", "sequence": { "sequence": "MSGHKCSYPWDLHNRYPQDKSVVNKMQQKYWETKQAFIKATGKKEDEHVVASDADLDAKLELFHSIQRTCLDLSKAIVLYQKRICFLSQEENELGKFLRSQGFQDKTRAGKMMQATGKALCFSSQQRLALRNPLCRFHQEVETFRHRAISDTWLTVNRMEQCRTEYRGALLWMKDVSQELDPDLCKQMEKFRKVQTQVRLAKKSFDKLKMDVCQKVDLLGASRCNLLSHMLATYQTTLLHFWEKTSHTMAAIHESFRGYQPYEFTTLKSLQDPMRKLVEKEEKKRIAQQESAEAVAEEPSQLISLEDENQHKESSSFKTCLGPMAGTPEPEGADKDDLLLLSEIFNASSLEEGEFSKEWAAVFGDGRLKEPMPTAAPGELDPRPQAGSGFLPSQLLDQNIKDLQASLEGWSESSVSPSPPWPAPKASSANVNYPAVKEPAKASSDLTAWFSLFADLDPLSNPDAIGKTDKEHELLNA", "length": 477, "header": "tr|A0A3Q1M1Y0-1|A0AAA9TV31_BOVIN Computationally mapped isoform of Islet cell autoantigen 1 OS=Bos taurus OX=9913 GN=ICA1 PE=4 SV=2 CANONICAL=A0AAA9TV31-1" }, "locus": { "chromosome": "4", "start_pos": 16329094, "end_pos": 16192445, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000074256.2", "url": "https://www.ensembl.org/id/ENSBTAT00000074256.2" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000067377.2", "url": "https://www.ensembl.org/id/ENSBTAP00000067377.2" } ] } }, { "isoform_ac": "A0A3Q1MG19-1", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1MG19/entry", "sequence": { "sequence": "MSGHKCYPWDLHNRYPQDKSVVNKMQQKYWETKQAFIKATGKKEDEHVVASDADLDAKLELFHSIQRTCLDLSKAIVLYQKRICFLSQEENELGKFLRSQGFQDKTRAGKMMQATGKALCFSSQQRLALRNPLCRFHQEVETFRHRAISDTWLTVNRMEQCRTEYRGALLWMKDVSQELDPDLCKQMEKFRKVQTQVRLAKKSFDKLKMDVCQKVDLLGASRCNLLSHMLATYQTTLLHFWEKTSHTMAAIHESFRGYQPYEFTTLKSLQDPMRKLVEKEEKKRIAQQESAEAVAEEPSQLISLEDENQHKESSSFKTEDRKSVLSALDKSCTHNACAEPVDELLDMKPEEGACLGPMAGTPEPEGADKDDLLLLSEIFNASSLEEGEFSKEWAAVFGDGRLKEPMPTAAPGELDPRPQAGSGFLPSQLLDQNIKDLQASLEEPAKASSDLTAWFSLFADLDPLSNPDAIGKTDKEHELLNA", "length": 482, "header": "tr|A0A3Q1MG19-1|A0AAA9TV31_BOVIN Computationally mapped isoform of Islet cell autoantigen 1 OS=Bos taurus OX=9913 GN=ICA1 PE=4 SV=2 CANONICAL=A0AAA9TV31-1" }, "locus": { "chromosome": "4", "start_pos": 16329094, "end_pos": 16192445, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000081695.3", "url": "https://www.ensembl.org/id/ENSBTAT00000081695.3" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000069488.2", "url": "https://www.ensembl.org/id/ENSBTAP00000069488.2" } ] } }, { "isoform_ac": "A0A3Q1N2K1-1", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1N2K1/entry", "sequence": { "sequence": "MSGHKCSYPWDLHNRYPQDKSVVNKMQQKYWETKQAFIKATGKKEDEHVVASDADLDAKLELFHSIQRTCLDLSKAIVLYQKRICFLSQEENELGKFLRSQGFQDKTRAGKMMQATGKALCFSSQQRLALRNPLCRFHQEVETFRHRAISDTWLTVNRMEQCRTEYRGALLWMKDVSQELDPDLCKQMEKFRKVQTQVRLAKKSFDKLKMDVCQKVDLLGASRCNLLSHMLATYQTTLLHFWEKTSHTMAAIHESFRGYQPYEFTTLKSLQDPMRKLVEKEEKKRIAQQESAEAVAEEPSQLISLEDENQHKESSSFKTEDRKSVLSALDKSCTHNACADELLDMKPEEGACLGPMAGTPEPEGADKDDLLLLSEIFNASSLEEGEFSKEWAAVFGDGRLKEPMPTAAPGELDPRPQAGSGFLPSQLLDQNIKDLQASLEGNLPDPGTEPQSPALQADCLPSESPGKPF", "length": 469, "header": "tr|A0A3Q1N2K1-1|A0AAA9TV31_BOVIN Computationally mapped isoform of Islet cell autoantigen 1 OS=Bos taurus OX=9913 GN=ICA1 PE=4 SV=2 CANONICAL=A0AAA9TV31-1" }, "locus": { "chromosome": "4", "start_pos": 16329094, "end_pos": 16195024, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000074033.2", "url": "https://www.ensembl.org/id/ENSBTAT00000074033.2" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000063518.2", "url": "https://www.ensembl.org/id/ENSBTAP00000063518.2" } ] } }, { "isoform_ac": "A0AAA9TV31-1", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TV31/entry", "sequence": { "sequence": "MSGHKCSYPWDLHNRYPQDKSVVNKMQQKYWETKQAFIKATGKKEDEHVVASDADLDAKLELFHSIQRTCLDLSKAIVLYQKRICFLSQEENELGKFLRSQGFQDKTRAGKMMQATGKALCFSSQQRLALRNPLCRFHQEVETFRHRAISDTWLTVNRMEQCRTEYRGALLWMKDVSQELDPDLCKQMEKFRKVQTQVRLAKKSFDKLKMDVCQKVDLLGASRCNLLSHMLATYQTTLLHFWEKTSHTMAAIHESFRGYQPYEFTTLKSLQDPMRKLVEKEEKKRIAQQESAEAVAEEPSQLISLEDENQHKESSSFKTEDRKSVLSALDKSCTHNACADELLDMKPEEGACLGPMAGTPEPEGADKDDLLLLSEIFNASSLEEGEFSKEWAAVFGDGRLKEPMPTAAPGELDPRPQAGSGFLPSQLLDQNIKDLQASLEGWSESSVSPSPPWPAPKASSANVNYPAVKEPAKASSDLTAWFSLFADLDPLSNPDAIGKTDKEHELLNA", "length": 509, "header": "tr|A0AAA9TV31-1|A0AAA9TV31_BOVIN Isoform 1 of Islet cell autoantigen 1 OS=Bos taurus OX=9913 GN=ICA1 PE=4 SV=1 CANONICAL=A0AAA9TV31-1" }, "locus": { "chromosome": "4", "start_pos": 16329094, "end_pos": 16192445, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000126758.1", "url": "https://www.ensembl.org/id/ENSBTAT00000126758.1" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000101247.1", "url": "https://www.ensembl.org/id/ENSBTAP00000101247.1" } ] } }, { "isoform_ac": "F1MW75-1", "url": "https://www.uniprot.org/uniprotkb/F1MW75/entry", "sequence": { "sequence": "MSGHKCSYPWDLHNRYPQDKSVVNKMQQKYWETKQAFIKATGKKEDEHVVASDADLDAKLELFHSIQRTCLDLSKAIVLYQKRICFLSQEENELGKFLRSQGFQDKTRAGKMMQATGKALCFSSQQRLALRNPLCRFHQEVETFRHRAISDTWLTVNRMEQCRTEYRGALLWMKDVSQELDPDLCKQMEKFRKVQTQVRLAKKSFDKLKMDVCQKVDLLGASRCNLLSHMLATYQTTLLHFWEKTSHTMAAIHESFRGYQPYEFTTLKSLQDPMRKLVEKEEKKRIAQQESAEAVAEEPSQLISLEDENQHKESSSFKNELLDMKPEEGACLGPMAGTPEPEGADKDDLLLLSEIFNASSLEEGEFSKEWAAVFGDGRLKEPMPTAAPGELDPRPQAGSGFLPSQLLDQNIKDLQASLEEPAKASSDLTAWFSLFADLDPLSNPDAIGKTDKEHELLNA", "length": 459, "header": "tr|F1MW75-1|A0AAA9TV31_BOVIN Computationally mapped isoform of Islet cell autoantigen 1 OS=Bos taurus OX=9913 GN=ICA1 PE=4 SV=2 CANONICAL=A0AAA9TV31-1" }, "locus": { "chromosome": "4", "start_pos": 16329094, "end_pos": 16192445, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000001057.6", "url": "https://www.ensembl.org/id/ENSBTAT00000001057.6" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000001057.5", "url": "https://www.ensembl.org/id/ENSBTAP00000001057.5" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [], "orthologs": [], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 6, "go_terms": [ { "name": "cytoplasm", "id": "GO:0005737", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005737", "evidence": [ { "database": "UniProtKB", "id": "A0AAA9TV31", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TV31" } ], "pmid": "" }, { "name": "endomembrane system", "id": "GO:0012505", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0012505", "evidence": [ { "database": "UniProtKB", "id": "A0AAA9TV31", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TV31" } ], "pmid": "" }, { "name": "Golgi membrane", "id": "GO:0000139", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000139", "evidence": [ { "database": "UniProtKB", "id": "A0AAA9TV31", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TV31" } ], "pmid": "" }, { "name": "cytosol", "id": "GO:0005829", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005829", "evidence": [ { "database": "UniProtKB", "id": "A0AAA9TV31", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TV31" } ], "pmid": "" }, { "name": "secretory granule membrane", "id": "GO:0030667", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030667", "evidence": [ { "database": "UniProtKB", "id": "A0AAA9TV31", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TV31" } ], "pmid": "" }, { "name": "synaptic vesicle membrane", "id": "GO:0030672", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030672", "evidence": [ { "database": "UniProtKB", "id": "A0AAA9TV31", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TV31" } ], "pmid": "" } ] }, { "name": "Molecular Function", "total": 2, "go_terms": [ { "name": "protein domain specific binding", "id": "GO:0019904", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0019904", "evidence": [ { "database": "UniProtKB", "id": "A0AAA9TV31", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TV31" } ], "pmid": "" }, { "name": "membrane curvature sensor activity", "id": "GO:0140090", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0140090", "evidence": [ { "database": "UniProtKB", "id": "A0AAA9TV31", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TV31" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 2, "go_terms": [ { "name": "membrane bending", "id": "GO:0097753", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0097753", "evidence": [ { "database": "UniProtKB", "id": "A0AAA9TV31", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TV31" } ], "pmid": "" }, { "name": "regulation of secretion", "id": "GO:0051046", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0051046", "evidence": [ { "database": "UniProtKB", "id": "A0AAA9TV31", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TV31" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 378, "end_pos": 380, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], 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"n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ], "tool_support": { "graph_view": "yes" } }, { "uniprot_canonical_ac": "A0AAA9TSB3-1", "uniprot_ac": "A0AAA9TSB3", "uniprot_id": "A0AAA9TSB3_BOVIN", "mass": { "chemical_mass": 88841.0, "monoisotopic_mass": 88841.0 }, "refseq": {}, "gene_names": [ { "name": "ALDH16A1", "type": "recommended", "evidence": [ { "id": "A0AAA9TSB3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TSB3" } ] } ], "protein_names": [ { "name": "Aldehyde dehydrogenase family 16 member A1", "type": "recommended", "evidence": [ { "id": "A0AAA9TSB3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TSB3/entry#names_and_taxonomy" } ] } ], "function": [], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Bos taurus", "taxid": 9913, "evidence": [ { "database": "UniProtKB", "id": "A0AAA9TSB3", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TSB3" } ], "common_name": "Bovine", "glygen_name": "Bovine", "reference_species": "Bos taurus [9913]" } ], "gene": [ { "name": "ALDH16A1", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TSB3", "locus": { "chromosome": "18", "start_pos": 55930058, "end_pos": 55910300, "strand": "-", "evidence": [ { "database": "Ensembl Gene", "id": "ENSBTAG00000000330", "url": "https://www.ensembl.org/id/ENSBTAG00000000330" } ] } } ], "crossref": [ { "id": "A0AAA9TSB3", "url": "https://alphafold.ebi.ac.uk/entry/A0AAA9TSB3", "database": "AlphaFoldDB", "categories": [] }, { "id": "ENSBTAG00000000330", "url": "https://bgee.org/?page=gene&gene_id=ENSBTAG00000000330", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "cd07111", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd07111", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "IPR011408", "url": "https://www.ebi.ac.uk/interpro/entry/IPR011408", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR015590", "url": "https://www.ebi.ac.uk/interpro/entry/IPR015590", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR016161", "url": "https://www.ebi.ac.uk/interpro/entry/IPR016161", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR016162", "url": "https://www.ebi.ac.uk/interpro/entry/IPR016162", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR016163", "url": "https://www.ebi.ac.uk/interpro/entry/IPR016163", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "A0A3Q1M2H4", "url": "https://www.orthodb.org/?gene=A0A3Q1M2H4", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "F1N441", "url": "https://www.orthodb.org/?gene=F1N441", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR11699", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR11699", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00171", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00171", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "A0A3Q1M2H4", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1M2H4", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A3Q1M2H4-1", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1M2H4-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0AAA9S282", "url": "https://www.uniprot.org/uniprotkb/A0AAA9S282", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0AAA9S282-1", "url": "https://www.uniprot.org/uniprotkb/A0AAA9S282-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0AAA9SGZ8", "url": "https://www.uniprot.org/uniprotkb/A0AAA9SGZ8", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0AAA9SGZ8-1", "url": "https://www.uniprot.org/uniprotkb/A0AAA9SGZ8-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0AAA9TG14", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TG14", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0AAA9TG14-1", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TG14-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0AAA9TSB3", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TSB3", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0AAA9TSB3-1", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TSB3-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "F1N441", "url": "https://www.uniprot.org/uniprotkb/F1N441", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "F1N441-1", "url": "https://www.uniprot.org/uniprotkb/F1N441-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MRTGEGLPGSALPIPLRGLQGPVLRADSRDPPRQLSSSAPSAPAASQDPGWRAFPWPLTVVVSLPAWLDTQDRHLGHYVNGQWLKPEHRSSVPCQDPITGENLASCLQAQSEDVAAAVEAARASLENWSTQPGAIRAQHLTRLAKVIQKHQRLLWTLESLVTGRAVREVRDRDVPLAQQLLQYHAVQAHTQEEALAGWEPMGVIGLILSPTFPFLDMMWRICPALAVGCTVVVLVPPASPTPLLLAQLAGELGPFPGILNVISGPASLGPVLAAQPGVQKVAFCGAIEEGRALRRTLAGWVPELGLALGAESLLLLTEVADVDSAVEGIVDAAWSDRSPGGLRLLIQEAVWDETMRRLQERMGRLRCGHGLDGAVDMGARGAAARDLAQRYVSEAQSQGAQVFQAGSEPSDSPFFPPTLVSDLPPASPCTQAEVPWPLVVASPFRTAKEALAVANGTPRGGSASVWSERLGQALELAYGLQVGTVWINAHGLRDPAVPMGGCKESGSSWHGGQDGLYEYLRPSGTPAWIPYLSKTLNYDAFGLALPSTLPAGPETGPAPPYGLFVGGRFQAPGARSSRPIRDSQGSLQGYVAEGGAKDIRGAVEAAHQAAPGWMSQSPAARAALLWALAAALQRREPNLVSRLERHGVELKVAKAEVELSVKRLRAWGARVQAQGCALQVAELRGPVLRLREPLGVLAIVCPDEWPLLAFVSLLAPALAHGNTVVLVPSGACPIPALEVCQEMATLLPAGLVNVVTGDRDHLTRCLALHQDIQALWYFGSAQGSQFVEWASAGNLKPVWVNRGCPRAWDQEAEGAGPELGRRAARTKALWLPMGD", "length": 835, "header": "tr|A0AAA9TSB3-1|A0AAA9TSB3_BOVIN Isoform 1 of Aldehyde dehydrogenase family 16 member A1 OS=Bos taurus OX=9913 GN=ALDH16A1 PE=3 SV=1 CANONICAL=A0AAA9TSB3-1" }, "isoforms": [ { "isoform_ac": "A0A3Q1M2H4-1", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1M2H4/entry", "sequence": { "sequence": "MAATRTASRACEIFTTLEYGPAPESHACALAWLDTQDRHLGHYVNGQWLKPEHRSSVPCQDPITGENLASCLQAQSEDVAAAVEAARASLENWSTQPGAIRAQHLTRLAKVIQKHQRLLWTLESLVTGRAVREVRDRDVPLAQQLLQYHAVQAHTQEEALAGWEPMGVGSLDSSVLNYLLPPGCTVVVLVPPASPTPLLLAQLAGELGPFPGILNVISGPASLGPVLAAQPGVQKVAFCGAIEEGRALRRTLAGWVPELGLALGAESLLLLTEVADVDSAVEGIVDAAWSDRSPGGLRLLIQEAVWDETMRRLQERMGRLRCGHGLDGAVDMGARGAAARDLAQRYVSEAQSQGAQVFQAGSEPSDSPFFPPTLVSDLPPASPCTQAEVPWPLVVASPFRTAKEALAVANGTPRGGSASVWSERLGQALELAYGLQVGTVWINAHGLRDPAVPMGGCKESGSSWHGGQDVSNHLPAWGEGGFWAGAALTHPHPSSSCSPAPPYGLFVGGRFQAPGARSSRPIRDSQGSLQGYVAEGGAKDIRGAVEAAHQAAPGWMSQSPAARAALLWALAAALQRREPNLVSRLERHGVELKVAKAEVELSVKRLRAWGARVQAQGCALQVAELRGPVLRLREPLGVLAIVCPDEWPLLAFVSLLAPALAHGNTVVLVPSGACPIPALEVCQPVDMLTMPLCLSPHQGSQFVEWASAGNLKPVWVNRGCPRAWDQEAEGAGPELGRRAARTKALWLPMGD", "length": 751, "header": "tr|A0A3Q1M2H4-1|A0AAA9TSB3_BOVIN Computationally mapped isoform of Aldehyde dehydrogenase family 16 member A1 OS=Bos taurus OX=9913 GN=ALDH16A1 PE=3 SV=1 CANONICAL=A0AAA9TSB3-1" }, "locus": { "chromosome": "18", "start_pos": 55924350, "end_pos": 55910419, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000070408.3", "url": "https://www.ensembl.org/id/ENSBTAT00000070408.3" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000067618.1", "url": "https://www.ensembl.org/id/ENSBTAP00000067618.1" } ] } }, { "isoform_ac": "A0AAA9S282-1", "url": "https://www.uniprot.org/uniprotkb/A0AAA9S282/entry", "sequence": { "sequence": "MRTGVIGLILSPTFPFLDMMWRICPALAVGCTVVVLVPPASPTPLLLAQLAGELGPFPGILNVISGPASLGPVLAAQPGVQKVAFCGAIEEGRALRRTLAGWVPELGLALGAESLLLLTEVADVDSAVEGIVDAAWSDRSPGGLRLLIQEAVWDETMRRLQERMGRLRCGHGLDGAVDMGARGAAARDLAQRYVSEAQSQGAQVFQAGSEPSDSPFFPPTLVSDLPPASPCTQAEVPWPLVVASPFRTAKEALAVANGTPRGGSASVWSERLGQALELAYGLQVGTVWINAHGLRDPAVPMGGCKESGSSWHGGQDGLYEYLRPSGTPAWIPYLSKTLNYDAFGLALPSTLPAGPETGPAPPYGLFVGGRFQAPGARSSRPIRDSQGSLQGYVAEGGAKDIRGAVEAAHQAAPGWMSQSPAARAALLWALAAALQRREPNLVSRLERHGVELKVAKAEVELSVKRLRAWGARVQAQGCALQVAELRGPVLRLREPLGVLAIVCPDEWPLLAFVSLLAPALAHGNTVVLVPSGACPIPALEVCQEMATLLPAGLVNVVTGDRDHLTRCLALHQDIQALWYFGSAQGSQFVEWASAGNLKPVWVNRGCPRAWDQEAEGAGPELGRRAARTKALWLPMGD", "length": 637, "header": "tr|A0AAA9S282-1|A0AAA9TSB3_BOVIN Computationally mapped isoform of Aldehyde dehydrogenase family 16 member A1 OS=Bos taurus OX=9913 GN=ALDH16A1 PE=3 SV=1 CANONICAL=A0AAA9TSB3-1" }, "locus": { "chromosome": "18", "start_pos": 55924350, "end_pos": 55910499, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000132029.1", "url": "https://www.ensembl.org/id/ENSBTAT00000132029.1" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000076203.1", "url": "https://www.ensembl.org/id/ENSBTAP00000076203.1" } ] } }, { "isoform_ac": "A0AAA9SGZ8-1", "url": "https://www.uniprot.org/uniprotkb/A0AAA9SGZ8/entry", "sequence": { "sequence": "MAATRTASRACEIFTTLEYGPAPESHACALAWLDTQDRHLGHYVNGQWLKPEHRSSVPCQDPITGENLASCLQAQSEDVAAAVEAARASLENWSTQPGAIRAQHLTRLAKVIQKHQRLLWTLESLVTGRAVREVRDRDVPLAQQLLQYHAVQAHTQEEALAGWEPMGVIGLILSPTFPFLDMMWRICPALAVGCTVVVLVPPASPTPLLLAQLAGELGPFPGILNVISGPASLGPVLAAQPGVQKVAFCGAIEEGRALRRTLAGWVPELGLALGAESLLLLTEVADVDSAVEGIVDAAWSDRSPGGLRLLIQEAVWDETMRRLQERMGRLRCGHGLDGAVDMGARGAAARDLAQRYVSEAQSQGAQVFQAGSEPSDSPFFPPTLVSDLPPASPCTQAEVPWPLVVASPFRTAKEALAVANGTPRGGSASVWSERLGQALELAYGLQVGTVWINAHGLRDPAVPMGGCKESGSSWHGGQDGLYEYLRPSGTPAWIPYLSKTLNYDAFGLALPSTLPAGPETGPAPPYGLFVGGRFQAPGARSSRPIRDSQGSLQGYVAEGGAKDIRGAVEAAHQAAPGWMSQSPAARAALLWALAAALQRREPNLVSRLERHGVELKVAKAEVELSVKRLRAWGARVQAQGCALQEMATLLPAGLVNVVTGDRDHLTRCLALHQDIQALWYFGSAQGSQFVEWASAGNLKPVWVNRGCPRAWDQEAEGAGPELGRRAARTKALWLPMGD", "length": 738, "header": "tr|A0AAA9SGZ8-1|A0AAA9TSB3_BOVIN Computationally mapped isoform of Aldehyde dehydrogenase family 16 member A1 OS=Bos taurus OX=9913 GN=ALDH16A1 PE=3 SV=1 CANONICAL=A0AAA9TSB3-1" }, "locus": { "chromosome": "18", "start_pos": 55924350, "end_pos": 55910419, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000107542.2", "url": "https://www.ensembl.org/id/ENSBTAT00000107542.2" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000082969.1", "url": "https://www.ensembl.org/id/ENSBTAP00000082969.1" } ] } }, { "isoform_ac": "A0AAA9TG14-1", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TG14/entry", "sequence": { "sequence": "MAATRTASRACEIFTTLEYGPAPESHACALAWLDTQDRHLGHYVNGQWLKPEHRSSVPCQDPITGENLASCLQAQSEDVAAAVEAARASLENWSTQPGAIRAQHLTRLAKVIQKHQRLLWTLESLVTGRAVREVRDRDVPLAQQLLQYHAVQAHTQEEALAGWEPMGVIGLILSPTFPFLDMMWRICPALAVGCTVVVLVPPASPTPLLLAQLAGELGPFPGILNVISGPASLGPVLAAQPGVQKVAFCGAIEEGRALRRTLAGWVPELGLALGAESLLLLTEVADVDSAVEGIVDAAWSDRSPGGLRLLIQEAVWDETMRRLQERMGRLRCGHGLDGAVDMGARGAAARDLAQRYVSEAQSQGAQVFQAGSEPSDSPFFPPTLVSDLPPASPCTQAEVPWPLVVASPFRTAKEALAVANGTPRGGSASVWSERLGQALELAYGLQVGTVWINAHGLRDPAVPMGGCKESGSSWHGGQDGLYEYLRPSGTPAWIPYLSKTLNYDAFGLALPSTLPAGPETGPAPPYGLFVGGRFQAPGARSSRPIRDSQGSLQGYVAEGGAKDIRGAVEAAHQAAPGWMSQSPAARAALLWALAAALQRREPNLVSRLERHGVELKVAKAEVELSVKRLRAWGARVQAQGCALQVAELRGPVLRLREPLGVLAIVCPDEWPLLAFVSLLAPALAHGNTVVLVPSGACPIPALEVCQEMATLLPAGLVNVVTGDRDHLTRCLALHQDIQALWYFGSAQIRPQA", "length": 752, "header": "tr|A0AAA9TG14-1|A0AAA9TSB3_BOVIN Computationally mapped isoform of Aldehyde dehydrogenase family 16 member A1 OS=Bos taurus OX=9913 GN=ALDH16A1 PE=3 SV=1 CANONICAL=A0AAA9TSB3-1" }, "locus": { "chromosome": "18", "start_pos": 55930025, "end_pos": 55910419, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000095813.2", "url": "https://www.ensembl.org/id/ENSBTAT00000095813.2" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000097504.1", "url": "https://www.ensembl.org/id/ENSBTAP00000097504.1" } ] } }, { "isoform_ac": "A0AAA9TSB3-1", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TSB3/entry", "sequence": { "sequence": "MRTGEGLPGSALPIPLRGLQGPVLRADSRDPPRQLSSSAPSAPAASQDPGWRAFPWPLTVVVSLPAWLDTQDRHLGHYVNGQWLKPEHRSSVPCQDPITGENLASCLQAQSEDVAAAVEAARASLENWSTQPGAIRAQHLTRLAKVIQKHQRLLWTLESLVTGRAVREVRDRDVPLAQQLLQYHAVQAHTQEEALAGWEPMGVIGLILSPTFPFLDMMWRICPALAVGCTVVVLVPPASPTPLLLAQLAGELGPFPGILNVISGPASLGPVLAAQPGVQKVAFCGAIEEGRALRRTLAGWVPELGLALGAESLLLLTEVADVDSAVEGIVDAAWSDRSPGGLRLLIQEAVWDETMRRLQERMGRLRCGHGLDGAVDMGARGAAARDLAQRYVSEAQSQGAQVFQAGSEPSDSPFFPPTLVSDLPPASPCTQAEVPWPLVVASPFRTAKEALAVANGTPRGGSASVWSERLGQALELAYGLQVGTVWINAHGLRDPAVPMGGCKESGSSWHGGQDGLYEYLRPSGTPAWIPYLSKTLNYDAFGLALPSTLPAGPETGPAPPYGLFVGGRFQAPGARSSRPIRDSQGSLQGYVAEGGAKDIRGAVEAAHQAAPGWMSQSPAARAALLWALAAALQRREPNLVSRLERHGVELKVAKAEVELSVKRLRAWGARVQAQGCALQVAELRGPVLRLREPLGVLAIVCPDEWPLLAFVSLLAPALAHGNTVVLVPSGACPIPALEVCQEMATLLPAGLVNVVTGDRDHLTRCLALHQDIQALWYFGSAQGSQFVEWASAGNLKPVWVNRGCPRAWDQEAEGAGPELGRRAARTKALWLPMGD", "length": 835, "header": "tr|A0AAA9TSB3-1|A0AAA9TSB3_BOVIN Isoform 1 of Aldehyde dehydrogenase family 16 member A1 OS=Bos taurus OX=9913 GN=ALDH16A1 PE=3 SV=1 CANONICAL=A0AAA9TSB3-1" }, "locus": { "chromosome": "18", "start_pos": 55924350, "end_pos": 55910499, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000106668.1", "url": "https://www.ensembl.org/id/ENSBTAT00000106668.1" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000099925.1", "url": "https://www.ensembl.org/id/ENSBTAP00000099925.1" } ] } }, { "isoform_ac": "F1N441-1", "url": "https://www.uniprot.org/uniprotkb/F1N441/entry", "sequence": { "sequence": "MAATRTASRACEIFTTLEYGPAPESHACALAWLDTQDRHLGHYVNGQWLKPEHRSSVPCQDPITGENLASCLQAQSEDVAAAVEAARASLENWSTQPGAIRAQHLTRLAKVIQKHQRLLWTLESLVTGRAVREVRDRDVPLAQQLLQYHAVQAHTQEEALAGWEPMGVIGLILSPTFPFLDMMWRICPALAVGCTVVVLVPPASPTPLLLAQLAGELGPFPGILNVISGPASLGPVLAAQPGVQKVAFCGAIEGGLRLLIQEAVWDETMRRLQERMGRLRCGHGLDGAVDMGARGAAARDLAQRYVSEAQSQGAQVFQAGSEPSDSPFFPPTLVSDLPPASPCTQAEVPWPLVVASPFRTAKEALAVANGTPRGGSASVWSERLGQALELAYGLQVGTVWINAHGLRDPAVPMGGCKESGSSWHGGQDGLYEYLRPSGTPAWIPYLSKTLNYDAFGLALPSTLPAGPETGPAPPYGLFVGGRFQAPGARSSRPIRDSQGSLQGYVAEGGAKDIRGAVEAAHQAAPGWMSQSPAARAALLWALAAALQRREPNLVSRLERHGVELKVAKAEVELSVKRLRAWGARVQAQGCALQVAELRGPVLRLREPLGVLAIVCPDEWPLLAFVSLLAPALAHGNTVVLVPSGACPIPALEVCQEMATLLPAGLVNVVTGDRDHLTRCLALHQDIQALWYFGSAQGSQFVEWASAGNLKPVWVNRGCPRAWDQEAEGAGPELGRRAARTKALWLPMGD", "length": 749, "header": "tr|F1N441-1|F1N441_BOVIN Computationally mapped isoform of Aldehyde dehydrogenase family 16 member A1 OS=Bos taurus OX=9913 GN=ALDH16A1 PE=3 SV=4 CANONICAL=A0AAA9TSB3-1" }, "locus": { "chromosome": "18", "start_pos": 55924350, "end_pos": 55910419, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000043139.6", "url": "https://www.ensembl.org/id/ENSBTAT00000043139.6" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000040728.5", "url": "https://www.ensembl.org/id/ENSBTAP00000040728.5" } ] } } ], "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "other", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 525, "start_aa": "Thr", "end_pos": 525, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr525", "evidence": [ { "id": "", "database": "GlyGen", "url": "https://data.glygen.org/" } ], "filter_code": "000000000000000010000.00000000001000.0.01000" } ], "phosphorylation": [], "glycation": [], "keywords": [ "glycoprotein", 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"url": "https://alphafold.ebi.ac.uk/entry/A0AAA9TVE3", "database": "AlphaFoldDB", "categories": [] }, { "id": "ENSBTAG00000007141", "url": "https://bgee.org/?page=gene&gene_id=ENSBTAG00000007141", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "cd01273", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd01273", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "cd14686", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd14686", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "IPR006020", "url": "https://www.ebi.ac.uk/interpro/entry/IPR006020", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR011993", "url": "https://www.ebi.ac.uk/interpro/entry/IPR011993", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR051133", "url": "https://www.ebi.ac.uk/interpro/entry/IPR051133", "database": "InterPro", "categories": [ "Protein 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"FLGSTEVEQPKGTEVVRDAVRKLKFARHIKKSEGQKIPKVELQISIYGVKILEPKTKEVQHNCQLHRISFCADDKTDKRIFTFICKDSESNKHLCYVFDSEKCAEEITLTIGQAFDLAYRKFLESGGKDVETRKQIAGLQKRNLVFSCDFVSLPDASHGDQSSRSSRCWIQDLETENMELKNKVQDLENQLRITHVSTPPAGSVTPKSPSTDIFDMIPFSPVSHQSSIPTHNGMQPPPVPSRSNEIKRDLFGAEPFDPFNCGAGDFPPDIQSKLDEMQEGFKMGLTLEGTVFCLDPLDSRC", "length": 301, "header": "tr|A0A3Q1M7N7-1|A0AAA9TVE3_BOVIN Computationally mapped isoform of PTB domain-containing engulfment adapter protein 1 OS=Bos taurus OX=9913 GN= PE=3 SV=2 CANONICAL=A0AAA9TVE3-1" }, "locus": { "chromosome": "2", "start_pos": 7906166, "end_pos": 7839580, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000070330.2", "url": "https://www.ensembl.org/id/ENSBTAT00000070330.2" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000066084.2", "url": "https://www.ensembl.org/id/ENSBTAP00000066084.2" } ] } }, { "isoform_ac": "A0AAA9SG06-1", "url": "https://www.uniprot.org/uniprotkb/A0AAA9SG06/entry", "sequence": { "sequence": "FLGSTEVEQPKGTEVVRDAVRKLKFARHIKKSEGQKIPKVELQISIYGVKILEPKTKEVQHNCQLHRISFCADDKTDKRIFTFICKDSESNKHLCYVFDSEKCAEEITLTIGQAFDLAYRKFLESGGKDVETRKQIAGLQKRIQDLETENMELKNKVQDLENQLRITHVSTPPLLHKMSDHEQHGFQRCSPSFWHSTDDSSPCLNISSITVTPVNSPDSRLSLGLLIPPPSKRGLPKPDSDNSIPRPHAGSVTPKSPSTDIFDMIPFSPVSHQSSIPTHNGMQPPPVPSRSNEIKRDLFGAEPFDPFNCGAGDFPPDIQSKLDEMQRQRWRGSKWD", "length": 336, "header": "tr|A0AAA9SG06-1|A0AAA9TVE3_BOVIN Computationally mapped isoform of PTB domain-containing engulfment adapter protein 1 OS=Bos taurus OX=9913 GN= PE=3 SV=1 CANONICAL=A0AAA9TVE3-1" }, "locus": { "chromosome": "2", "start_pos": 7906166, "end_pos": 7839630, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000098370.1", "url": "https://www.ensembl.org/id/ENSBTAT00000098370.1" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000084302.1", "url": "https://www.ensembl.org/id/ENSBTAP00000084302.1" } ] } }, { "isoform_ac": "A0AAA9TFJ9-1", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TFJ9/entry", "sequence": { "sequence": "MNFLGSTEVEQPKGTEVVRDAVRKLKFARHIKKSEGQKIPKVELQISIYGVKILEPKTKEVQHNCQLHRISFCADDKTDKRIFTFICKDSESNKHLCYVFDSEKCAEEITLTIGQAFDLAYRKFLESGGKDVETRKQIAGLQKRIQDLETENMELKNKVQDLENQLRITHVSTPPAGSVTPKSPSTDIFDMIPFSPVSHQSSIPTHNGMQPPPVPSRSNEIKRDLFGAEPFDPFNCGAGDFPPDIQSKLDEMQEGFKMGLTLEGTVFCLDPLDSRC", "length": 276, "header": "tr|A0AAA9TFJ9-1|A0AAA9TVE3_BOVIN Computationally mapped isoform of PTB domain-containing engulfment adapter protein 1 OS=Bos taurus OX=9913 GN= PE=3 SV=1 CANONICAL=A0AAA9TVE3-1" }, "locus": { "chromosome": "2", "start_pos": 7906958, "end_pos": 7839580, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000132039.1", "url": "https://www.ensembl.org/id/ENSBTAT00000132039.1" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000095777.1", "url": "https://www.ensembl.org/id/ENSBTAP00000095777.1" } ] } }, { "isoform_ac": "A0AAA9TVE3-1", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TVE3/entry", "sequence": { "sequence": "FLGSTEVEQPKGTEVVRDAVRKLKFARHIKKSEGQKIPKVELQISIYGVKILEPKTKEVQHNCQLHRISFCADDKTDKRIFTFICKDSESNKHLCYVFDSEKCAEEITLTIGQAFDLAYRKFLESGGKDVETRKQIAGLQKRIQDLETENMELKNKVQDLENQLRITHVSTPPLLHKMSDHEQHGFQRCSPSFWHSTDDSSPCLNISSITVTPVNSPDSRLSLGLLIPPPSKRGLPKPDSDNSIPRPHAGSVTPKSPSTDIFDMIPFSPVSHQSSIPTHNGMQPPPVPSRSNEIKRDLFGAEPFDPFNCGAGDFPPDIQSKLDEMQEGFKMGLTLEGTVFCLDPLDSRC", "length": 349, "header": "tr|A0AAA9TVE3-1|A0AAA9TVE3_BOVIN Isoform 1 of PTB domain-containing engulfment adapter protein 1 OS=Bos taurus OX=9913 GN= PE=3 SV=1 CANONICAL=A0AAA9TVE3-1" }, "locus": { "chromosome": "2", "start_pos": 7906166, "end_pos": 7839580, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000112924.1", "url": "https://www.ensembl.org/id/ENSBTAT00000112924.1" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000101384.1", "url": "https://www.ensembl.org/id/ENSBTAP00000101384.1" } ] } }, { "isoform_ac": "F1MY30-1", "url": "https://www.uniprot.org/uniprotkb/F1MY30/entry", "sequence": { "sequence": "KFLGSTEVEQPKGTEVVRDAVRKLKFARHIKKSEGQKIPKVELQISIYGVKILEPKTKEVQHNCQLHRISFCADDKTDKRIFTFICKDSESNKHLCYVFDSEKCAEEITLTIGQAFDLAYRKFLESGGKDVETRKQIAGLQKRIQDLETENMELKNKVQDLENQLRITHVSTPPAGSVTPKSPSTDIFDMIPFSPVSHQSSIPTHNGMQPPPVPSRSNEIKRDLFGAEPFDPFNCGAGDFPPDIQSKLDEMQEGFKMGLTLEGTVFCLDPLDSRC", "length": 275, "header": "tr|F1MY30-1|A0AAA9TVE3_BOVIN Computationally mapped isoform of PTB domain-containing engulfment adapter protein 1 OS=Bos taurus OX=9913 GN= PE=3 SV=3 CANONICAL=A0AAA9TVE3-1" }, "locus": { "chromosome": "2", "start_pos": 7933250, "end_pos": 7839580, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000009398.7", "url": "https://www.ensembl.org/id/ENSBTAT00000009398.7" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000009398.6", "url": "https://www.ensembl.org/id/ENSBTAP00000009398.6" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [], "orthologs": [], "go_annotation": { 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"url": "https://www.uniprot.org/uniprotkb/A0AAA9TT40" } ], "pmid": "" }, { "name": "nuclear speck", "id": "GO:0016607", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016607", "evidence": [ { "database": "UniProtKB", "id": "A0AAA9TT40", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TT40" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 1, "go_terms": [ { "name": "regulation of stem cell population maintenance", "id": "GO:2000036", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:2000036", "evidence": [ { "database": "UniProtKB", "id": "A0AAA9TT40", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TT40" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 1161, "end_pos": 1163, "annotation": "n_glycosylation_sequon" }, { "start_pos": 1208, "end_pos": 1210, "annotation": "n_glycosylation_sequon" }, { "start_pos": 1211, "end_pos": 1213, "annotation": "n_glycosylation_sequon" }, { "start_pos": 1224, "end_pos": 1226, "annotation": 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"sort_fields": [] } ], "tool_support": { "graph_view": "yes" } }, { "uniprot_canonical_ac": "A0AAA9TUD4-1", "uniprot_ac": "A0AAA9TUD4", "uniprot_id": "A0AAA9TUD4_BOVIN", "mass": { "chemical_mass": 11954.0, "monoisotopic_mass": 11954.0 }, "refseq": {}, "gene_names": [], "protein_names": [ { "name": "Ig-like domain-containing protein", "type": "recommended", "evidence": [ { "id": "A0AAA9TUD4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TUD4/entry#names_and_taxonomy" } ] } ], "function": [], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Bos taurus", "taxid": 9913, "evidence": [ { "database": "UniProtKB", "id": "A0AAA9TUD4", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TUD4" } ], "common_name": "Bovine", "glygen_name": "Bovine", "reference_species": "Bos taurus [9913]" } ], "gene": [ { "name": "", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TUD4", "locus": {} } ], "crossref": [ { "id": "A0AAA9TUD4", "url": "https://alphafold.ebi.ac.uk/entry/A0AAA9TUD4", "database": "AlphaFoldDB", "categories": [] }, { "id": "IPR003599", "url": "https://www.ebi.ac.uk/interpro/entry/IPR003599", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR007110", "url": "https://www.ebi.ac.uk/interpro/entry/IPR007110", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR013106", "url": "https://www.ebi.ac.uk/interpro/entry/IPR013106", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR013783", "url": "https://www.ebi.ac.uk/interpro/entry/IPR013783", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR036179", "url": "https://www.ebi.ac.uk/interpro/entry/IPR036179", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR050150", "url": "https://www.ebi.ac.uk/interpro/entry/IPR050150", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "PTHR23267", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR23267", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF07686", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF07686", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "A0AAA9TUD4", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TUD4", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0AAA9TUD4-1", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TUD4-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "QAVLTQPSSVSGSLGQRVSITCSGSSSNIGSYNVGWYQQVPGSGLRTIIYGSSSRPSGVPDRFSGSKSGNTATLTISSLQAEDEADYFCVAYDSSSSIVTVLQARGEVRQKPALP", "length": 115, "header": "tr|A0AAA9TUD4-1|A0AAA9TUD4_BOVIN Isoform 1 of Ig-like domain-containing protein OS=Bos taurus OX=9913 GN= PE=4 SV=2 CANONICAL=A0AAA9TUD4-1" }, "isoforms": [ { "isoform_ac": "A0AAA9TUD4-1", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TUD4/entry", "sequence": { "sequence": "QAVLTQPSSVSGSLGQRVSITCSGSSSNIGSYNVGWYQQVPGSGLRTIIYGSSSRPSGVPDRFSGSKSGNTATLTISSLQAEDEADYFCVAYDSSSSIVTVLQARGEVRQKPALP", "length": 115, "header": "tr|A0AAA9TUD4-1|A0AAA9TUD4_BOVIN Isoform 1 of Ig-like domain-containing protein OS=Bos taurus OX=9913 GN= PE=4 SV=2 CANONICAL=A0AAA9TUD4-1" }, "locus": { "chromosome": "NKLS02001361.1", "start_pos": 7678, "end_pos": 7334, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000099681.2", "url": "https://www.ensembl.org/id/ENSBTAT00000099681.2" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000100986.2", "url": "https://www.ensembl.org/id/ENSBTAP00000100986.2" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [], "orthologs": [], "go_annotation": {}, "pro_annotation": [], "site_annotation": [], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A0AAA9TUD4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TUD4" }, { "id": "PS50835", "database": "PROSITE", "url": "https://prosite.expasy.org/PS50835" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "Ig-like", "eco_id": "ECO_0000259", "start_pos": 1, "end_pos": 100, "start_aa": "Gln", "end_aa": "Thr", "glycosite_overlap": [] } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ], "tool_support": { "graph_view": "yes" } }, { "uniprot_canonical_ac": "A0AAA9TS88-1", "uniprot_ac": "A0AAA9TS88", "uniprot_id": "A0AAA9TS88_BOVIN", "mass": { "chemical_mass": 64777.0, "monoisotopic_mass": 64777.0 }, "refseq": { "ac": "XP_003587323", "name": "F-box only protein 46", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_003587323" }, "gene_names": [ { "name": "FBXO46", "type": "recommended", "evidence": [ { "id": "A0AAA9TS88", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TS88" } ] }, { "name": "FBXO46", "type": "synonym", "evidence": [ { "id": "XP_003587323", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_003587323" } ] } ], "protein_names": [ { "name": "F-box only protein 46", "type": "synonym", "evidence": [ { "id": "XP_003587323", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_003587323" } ] }, { "name": "F-box protein 46", "type": "synonym", "evidence": [ { "id": "A0AAA9TS88", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TS88/entry#names_and_taxonomy" } ] } ], "function": [], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Bos taurus", "taxid": 9913, "evidence": [ { "database": "UniProtKB", "id": "A0AAA9TS88", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TS88" } ], "common_name": "Bovine", "glygen_name": "Bovine", "reference_species": "Bos taurus [9913]" } ], "gene": [ { "name": "FBXO46", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TS88", "locus": { "chromosome": "18", "start_pos": 53262017, "end_pos": 53304442, "strand": "+", "evidence": [ { "database": "Ensembl Gene", "id": "ENSBTAG00000065646", "url": "https://www.ensembl.org/id/ENSBTAG00000065646" } ] } } ], "crossref": [ { "id": "ENSBTAG00000048966", "url": "https://bgee.org/?page=gene&gene_id=ENSBTAG00000048966", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "100140560", "url": "https://www.ncbi.nlm.nih.gov/gene/100140560", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR001810", "url": "https://www.ebi.ac.uk/interpro/entry/IPR001810", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR036047", "url": "https://www.ebi.ac.uk/interpro/entry/IPR036047", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR039594", "url": "https://www.ebi.ac.uk/interpro/entry/IPR039594", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "bta:100140560", "url": "https://www.genome.jp/dbget-bin/www_bget?bta:100140560", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "CHYFKSI", "url": "https://omabrowser.org/oma/group/CHYFKSI/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "A0A3Q1MJ31", "url": "https://www.orthodb.org/?gene=A0A3Q1MJ31", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR16271", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR16271", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR16271:SF10", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR16271:SF10", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF12937", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF12937", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "XP_003587323", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_003587323", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A3Q1MJ31", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1MJ31", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A3Q1MJ31-1", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1MJ31-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0AAA9TS88", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TS88", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0AAA9TS88-1", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TS88-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MDRGGLLPFQLWCPRPFGTYSQNQPRPPSATLKPSACSEPGGGAEPEHGPAHSENTPPVLASDAPASQPAPLLSAAAAGDEGRVLLDTWYVIKPGNTKEKVAFFVAHQCGGGSRASSMKVKGHWGSDSSKAKRRRRCLESTKAPPDPGGQDGPPAAEGAPTSAGEDVDLLSVAEMVALVEQRAALALQSYPRPSTPAPVVFVSAEQGGPGKGLGSERRSGGGDCSRVAEAVAHFEAQRDNPPAKGLRKEERPGPGPGEVRIAFRISNGRESRAPDGSLPNGSGGRPSCAYPGSPGPGARAKDKITCDLYQLISPSRDALPSNVEFLLARADEASEGETPAPARPEDTPPAPPPPPARDCGASGFHVDVVVTGVVDECIFFGKDSTKNVKEETVCLTVSPEEPPPPGQLFFLQSRGQDGPPEPPPADSPATAPGPDDAEGTADTSLCRLYRHVSHDFLEIRFKIQRLLEPRQYMLVLPEHVLVKIFSFLPTRALAALKCTCHHFKGIIEAFGVRATDSRWSRDPLYRDDPCKQCRKRYEKGDVSLCRWHPKPYHHDLPYGRSYWMCCRRADRETPGCRLGLHDNNWVLPCNGPGAGGGRAGREEGR", "length": 605, "header": "tr|A0AAA9TS88-1|A0AAA9TS88_BOVIN Isoform 1 of F-box protein 46 OS=Bos taurus OX=9913 GN=FBXO46 PE=4 SV=1 CANONICAL=A0AAA9TS88-1" }, "isoforms": [ { "isoform_ac": "A0A3Q1MJ31-1", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1MJ31/entry", "sequence": { "sequence": "MDRGGLLPFQLWCPRPFGTYSQNQPRPPSATLKPSACSEPGGGAEPEHGPAHSENTPPVLASDAPASQPAPLLSAAAAGDEGRVLLDTWYVIKPGNTKEKVAFFVAHQCGGGSRASSMKVKGHWGSDSSKAKRRRRCLESTKAPPDPGGQDGPPAAEGAPTSAGEDVDLLSVAEMVALVEQRAALALQSYPRPSTPAPVVFVSAEQGGPGKGLGSERRSGGGDCSRVAEAVAHFEAQRDNPPAKGLRKEERPGPGPGEVRIAFRISNGRESRAPDGSLPNGSGGRPSCAYPGSPGPGARAKDKITCDLYQLISPSRDALPSNVEFLLARADEASEGETPAPARPEDTPPAPPPPPARDCGASGFHVDVVVTGVVDECIFFGKDSTKNVKEETVCLTVSPEEPPPPGQLFFLQSRGQDGPPEPPPADSPATAPGPDDAEGTADTSLCRLYRHVSHDFLEIRFKIQRLLEPRQYMLVLPEHVLVKIFSFLPTRALAALKCTCHHFKGIIEAFGVRATDSRWSRDPLYRDDPCKQCRKRYEKGDVSLCRWHPKPYHHDLPYGRSYWMCCRRADRETPGCRLGLHDNNWVLPCNGPGAGGGRAG", "length": 600, "header": "tr|A0A3Q1MJ31-1|A0AAA9TS88_BOVIN Computationally mapped isoform of F-box protein 46 OS=Bos taurus OX=9913 GN=FBXO46 PE=4 SV=2 CANONICAL=A0AAA9TS88-1" }, "locus": { "chromosome": "18", "start_pos": 53269348, "end_pos": 53267549, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000080440.2", "url": "https://www.ensembl.org/id/ENSBTAT00000080440.2" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000074344.2", "url": "https://www.ensembl.org/id/ENSBTAP00000074344.2" } ] } }, { "isoform_ac": "A0AAA9TS88-1", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TS88/entry", "sequence": { "sequence": "MDRGGLLPFQLWCPRPFGTYSQNQPRPPSATLKPSACSEPGGGAEPEHGPAHSENTPPVLASDAPASQPAPLLSAAAAGDEGRVLLDTWYVIKPGNTKEKVAFFVAHQCGGGSRASSMKVKGHWGSDSSKAKRRRRCLESTKAPPDPGGQDGPPAAEGAPTSAGEDVDLLSVAEMVALVEQRAALALQSYPRPSTPAPVVFVSAEQGGPGKGLGSERRSGGGDCSRVAEAVAHFEAQRDNPPAKGLRKEERPGPGPGEVRIAFRISNGRESRAPDGSLPNGSGGRPSCAYPGSPGPGARAKDKITCDLYQLISPSRDALPSNVEFLLARADEASEGETPAPARPEDTPPAPPPPPARDCGASGFHVDVVVTGVVDECIFFGKDSTKNVKEETVCLTVSPEEPPPPGQLFFLQSRGQDGPPEPPPADSPATAPGPDDAEGTADTSLCRLYRHVSHDFLEIRFKIQRLLEPRQYMLVLPEHVLVKIFSFLPTRALAALKCTCHHFKGIIEAFGVRATDSRWSRDPLYRDDPCKQCRKRYEKGDVSLCRWHPKPYHHDLPYGRSYWMCCRRADRETPGCRLGLHDNNWVLPCNGPGAGGGRAGREEGR", "length": 605, "header": "tr|A0AAA9TS88-1|A0AAA9TS88_BOVIN Isoform 1 of F-box protein 46 OS=Bos taurus OX=9913 GN=FBXO46 PE=4 SV=1 CANONICAL=A0AAA9TS88-1" }, "locus": { "chromosome": "18", "start_pos": 53269348, "end_pos": 53267534, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000133835.1", "url": "https://www.ensembl.org/id/ENSBTAT00000133835.1" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000086811.1", "url": "https://www.ensembl.org/id/ENSBTAP00000086811.1" } ] } } ], "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "other", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 195, "start_aa": "Thr", "end_pos": 195, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr195", "evidence": [ { "id": "", "database": "GlyGen", "url": "https://data.glygen.org/" } ], "filter_code": "000000000000000010000.00000000001000.0.01000" } ], "phosphorylation": [], "glycation": [], "keywords": [ "glycoprotein", "glycoprotein_predicted" ], "publication": [], "pathway": [ { "id": "bta:100140560", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?bta:100140560", "resource": "KEGG Pathway" } ], "orthologs": [ { "uniprot_canonical_ac": "A0A287AD84-1", "protein_name": "F-box protein 46", "gene_name": "FBXO46", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MDRGGLLPFQLWCPRPFGTYSQNQPRPPSAALKPAACSEPGSGAEPDHGPAHSENTPPALAAEAPASQPAPLLSAAAAGDEGRVLLDTWYVIKPGNTKEKVAFFVAHQCGGGSRASSMKVKGHWGSDSSKAKRRRRCLEPTKAPPDPGGQDGPPPAEGAPASASEDVDLLSVAEMVALVEQRAALALQNYSRPSAPAPVVFVSAEQGGPAKGLGSERRSGGGDCSRVAEAVAHFEAQRDSPPSKGLRKEERPGPGPGEVRIAFRISNGREPRAPDGGLPNGSGGRPGCAYPGSPGPGARAKDKITCDLYQLISPSRDALPSNVEFLLARADEASEGESPAPARPEDTPPAPPPPPARDCGASGFHVDVVVTGVVDECIFFGKDGTKNVKEETVCLTVSPEEPPPPGQLFFLQPRGPDGPPEPPPADAPAAAPGPDDAEGTTDTSLCRLYRHVSHDFLEIRFKIQRLLEPRQYMLLLPEHVLVKIFSFLPTRALAALKCTCHHFKGIIEAFGVRATDSRWSRDPLYRDDPCKQCRKRYEKGDVSLCRWHPKPYHHDLPYGRSYWMCCRRADRETPGCRLGLHDNNWVLPCNGPGGGGGARAGREEGR", "length": 606 }, "evidence": [ { "id": "A0AAA9TS88", "url": "https://omabrowser.org/oma/group/A0AAA9TS88/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "Q1L8N6-1", "protein_name": "F-box only protein 46", "gene_name": "fbxo46", "tax_id": 7955, "organism": "Danio rerio", "sequence": { "sequence": "MNRDTFSHIRLWCPRPFGTYSQNKPYSNGTVLNGTTTTHCKADDSGLTAIETHGVSEEQEEDVGTENTPPAASSTLLAPPLPASPSPNSQMEDGRVLLDTWYVIKPGNTKEKIAFFVAHQCNGAGIPRPSAMKVKGNWATDCTKAKRRRRCSSYDPPTKAQNVTVDVPAEPNLTDDGVVVSETDLLSVAEMVALVEQRTALALQGMVAQGQTSPYTVHQKPVVILSEPPSSTPASQSDFDLLQQQQESRRVAQTVAQFESRQQNLDSTTLRPELNGSGRDCIQTGESGTPSHGRGEVRIAFRVSSLDPRTQSEPVGRPKCMFMSCGVGGGQAAARGKEKITCDLYQLVSPSSRDPGALLAGSPKADPLGEGITDRPPSTTPDPNQDPASGEKATVARERVTGFHVEVVVTGAVDQCVFYGKDSTENVQEETVCFAMPNGAKSTDASEDPPPGQLFFLQSAATEDENCSAVNGGMRSLDCANNNGPLGATIERPDSPLATVDDCSDPPLCRLYRHVSHDFLEIRFQIQRLLEPRQYMLSLPDHIMVNIFSYLPTHSLAALKCTCHDFKTLIETYGVRATDSRWNQDPLYRDDPCKQCKRQYERGDVSLCRWHPKPYHHDLPYGRSYWMCCRRTDKDTPGCRVGLHDNNWVQPCELVQARKRDDAR", "length": 664 }, "evidence": [ { "id": "A0AAA9TS88", "url": "https://omabrowser.org/oma/group/A0AAA9TS88/", "database": "OMA" } ], "glygen_name": "Zebrafish", "common_name": "Zebrafish" }, { "uniprot_canonical_ac": "Q4KLY2-1", "protein_name": "F-box only protein 46", "gene_name": "Fbxo46", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MDRGSLLPFQLWCPRPFSKYSQNQPRPPSATLKPPVCPDTSSGTEPDHRPAHLESTPPALAAEAPTSQHAPLLSTAASGDEGRVLLDTWYVIKPGNTKEKVAFFVAHQCGGGSRASSMKVKGHWGSDSSKAKRRRRCLEPTKAPPDQGGQEGTPATEVAPTSSGDDVDLLSVAEMVALVEQRAALALQSYPRPSTPAPVVFVSAEQGGPAKGLGSERRSGGGDCSRVAEAVAHFEAQRDSPPTKGLRKEERPGPGPGEVRIAFRISNVREPQSPDGSLANGGGGRPACPYPGSPGPGTRAKDKITCDLYQLISPSRDALPSNVEFLLARADEASEGETPAPARPEDTPPAPPPPPARDCGASGFHVDVVVTGVVDACIFFGKDGTKNVKEETVCLTVSPEEPPPPGQLFFLQSRGPEGPPEPPPADTASKVPGPEDSEGTTDTSLCRLYRHVSHDFLEIRFKIQRLLEPRQYMLLLPEHVLVKIFSFLPTRALAALKCTCHHFKGIIEAFGVRATDSRWSRDPLYRDDPCKQCRKRYEKGDVSLCRWHPKPYHHDLPYGRSYWMCCRRADRETPGCRLGLHDNNWVLPCNGVGGGRAGREEGR", "length": 603 }, "evidence": [ { "id": "A0AAA9TS88", "url": "https://omabrowser.org/oma/group/A0AAA9TS88/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "Q6PJ61-1", "protein_name": "F-box only protein 46", "gene_name": "FBXO46", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MDRGSLLPFQLWCPRPFGTYSQNQPRPPSAALKPSACPEPGGGAEPDHGPAHSENTPPALATEVPASQPAPLLSAAAAGDEGRVLLDTWYVIKPGNTKEKVAFFVAHQCGGGSRASSMKVKGHWGSDSSKAKRRRRCLDPTKAPPDPGGREGPPAAEEGPASAGEDVDLLSVAEMVALVEQRAALALQSYPRPTTPAPVVFVSAEQGGPAKGVGSERRSGGGDCSRVAEAVAHFEAQRDSPPTKGLRKEERPGPGPGEVRIAFRISNGREPRAPDSGLPSGGGGRPGCAYPGSPGPGARAKDKITCDLYQLISPSRDALPSNVEFLLARADEASEGDSPAPARPEDTPPAPPPPPARDCGASGFHVDVVVTGVVDECIFFGKDGTKNVKEETVCLTVSPEEPPPPGQLFFLQNRGPDGPPEPPPADSPATAPGPDDAEGTADTSLCRLYRHVSHDFLEIRFKIQRLLEPRQYMLLLPEHVLVKIFSFLPTRALAALKCTCHHFKGIIEAFGVRATDSRWSRDPLYRDDPCKQCRKRYEKGDVSLCRWHPKPYHHDLPYGRSYWMCCRRADRETPGCRLGLHDNNWVLPCNGPGGGRAGREEGR", "length": 603 }, "evidence": [ { "id": "A0AAA9TS88", "url": "https://omabrowser.org/oma/group/A0AAA9TS88/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "Q8BG80-1", "protein_name": "F-box only protein 46", "gene_name": "Fbxo46", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MDRGSLLPFQLWCPRPFSKYSQNQPRPPSTALKPPVCPDTSSGTEPDHRPAHLESTPPAVAAEAPTSQPAPLLSTAASGDEGRVLLDTWYVIKPGNTKEKVAFFVAHQCGGSSRASSMKVKGHWGSDSSKAKRRRRCLEPTKAPPDQGGREGTPATEVTPTSSGDDVDLVSVAEMVALVEQRAALALQSYPRPSTPAPVVFVSADQGGPAKGLGSERRSGGGDCSRVAEAVAHFEAQRDSPPTKGLRKEERPGPGPGEVRIAFRISNVREPHSPDGNLPNGGGGRPGCAYPGSPGPGTRAKDKITCDLYQLISPSRDALPSNVEFLLARADEASEGETPAPTRPEDTPPAPPPPPARDCGASGFHVDVVVTGVVDACIFFGKDGTKNVKEETVCLTVSPEEPPPPGQLFFLQSRGPEGPPEPPPADIPSTVPGPDDSEGTTDTSLCRLYRHVSHDFLEIRFKIQRLLEPRQYMLLLPEHVLVKIFSFLPTRALAALKCTCHHFKGIIEAFGVRATDSRWSRDPLYRDDPCKQCRKRYEKGDVSLCRWHPKPYHHDLPYGRSYWMCCRRADRETPGCRLGLHDNNWVLPCNGVGGGRAGREEGR", "length": 603 }, "evidence": [ { "id": "A0AAA9TS88", "url": "https://omabrowser.org/oma/group/A0AAA9TS88/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" } ], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 1, "go_terms": [ { "name": "SCF ubiquitin ligase complex", "id": "GO:0019005", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0019005", "evidence": [ { "database": "UniProtKB", "id": "A0AAA9TS88", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TS88" } ], "pmid": "" } ] }, { "name": "Molecular Function", "total": 1, "go_terms": [ { "name": "ubiquitin-like ligase-substrate adaptor activity", "id": "GO:1990756", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:1990756", "evidence": [ { "database": "UniProtKB", "id": "A0AAA9TS88", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TS88" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 1, "go_terms": [ { "name": "SCF-dependent proteasomal ubiquitin-dependent protein catabolic process", "id": "GO:0031146", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0031146", "evidence": [ { "database": "UniProtKB", "id": "A0AAA9TS88", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TS88" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 280, "end_pos": 282, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A0AAA9TS88", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TS88" }, { "id": "PS50181", "database": "PROSITE", "url": "https://prosite.expasy.org/PS50181" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "F-box", "eco_id": "ECO_0000259", "start_pos": 470, "end_pos": 522, "start_aa": "Arg", "end_aa": "Asp", "glycosite_overlap": [] } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" }, { "name": "homologset.oma", "label": "OMA Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [ 195 ], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 280, "end_pos": 282 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 1 }, { "field": "total_sites", "count": 1 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 1 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "exact_sites", "count": 1 }, { "field": "exact_o_linked_sites", "count": 1 }, { "field": "fuzzy_sites", "count": 0 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_pos", "start_aa", "end_pos", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 1 }, { "field": "total_sites", "count": 1 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 1 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "exact_sites", "count": 1 }, { "field": "exact_o_linked_sites", "count": 1 }, { "field": "fuzzy_sites", "count": 0 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_pos", "start_aa", "end_pos", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ], "tool_support": { "graph_view": "yes" } }, { "uniprot_canonical_ac": "A0AAA9TV23-1", "uniprot_ac": "A0AAA9TV23", "uniprot_id": "A0AAA9TV23_BOVIN", "mass": { "chemical_mass": 46345.0, "monoisotopic_mass": 46345.0 }, "refseq": {}, "gene_names": [ { "name": "PDSS1", "type": "recommended", "evidence": [ { "id": "A0AAA9TV23", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TV23" } ] } ], "protein_names": [ { "name": "All trans-polyprenyl-diphosphate synthase PDSS1", "type": "recommended", "evidence": [ { "id": "A0AAA9TV23", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TV23/entry#names_and_taxonomy" } ] }, { "name": "2.5.1.91", "type": "synonym", "evidence": [ { "id": "A0AAA9TV23", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TV23/entry#names_and_taxonomy" } ] }, { "name": "All-trans-decaprenyl-diphosphate synthase subunit 1", "type": "synonym", "evidence": [ { "id": "A0AAA9TV23", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TV23/entry#names_and_taxonomy" } ] }, { "name": "Decaprenyl-diphosphate synthase subunit 1", "type": "synonym", "evidence": [ { "id": "A0AAA9TV23", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TV23/entry#names_and_taxonomy" } ] }, { "name": "Solanesyl-diphosphate synthase subunit 1", "type": "synonym", "evidence": [ { "id": "A0AAA9TV23", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TV23/entry#names_and_taxonomy" } ] }, { "name": "Trans-prenyltransferase 1", "type": "synonym", "evidence": [ { "id": "A0AAA9TV23", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TV23/entry#names_and_taxonomy" } ] } ], "function": [ { "annotation": "Heterotetrameric enzyme that catalyzes the condensation of farnesyl diphosphate (FPP), which acts as a primer, and isopentenyl diphosphate (IPP) to produce prenyl diphosphates of varying chain lengths and participates in the determination of the side chain of ubiquinone. Supplies nona and decaprenyl diphosphate, the precursors for the side chain of the isoprenoid quinones ubiquinone-9 (Q9)and ubiquinone-10 (Q10) respectively. The enzyme adds isopentenyl diphosphate molecules sequentially to farnesyl diphosphate with trans stereochemistry.", "evidence": [ { "database": "UniProtKB", "id": "A0AAA9TU73", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TU73#function" }, { "database": "UniProtKB", "id": "ARBA00057934", "url": "https://www.uniprot.org/uniprotkb/ARBA00057934#function" }, { "database": "UniProtKB", "id": "A0AAA9TV23", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TV23#function" }, { "database": "UniProtKB", "id": "A0A3Q1MLA7", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1MLA7#function" }, { "database": "UniProtKB", "id": "F6RJN8", "url": "https://www.uniprot.org/uniprotkb/F6RJN8#function" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Bos taurus", "taxid": 9913, "evidence": [ { "database": "UniProtKB", "id": "A0AAA9TV23", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TV23" } ], "common_name": "Bovine", "glygen_name": "Bovine", "reference_species": "Bos taurus [9913]" } ], "gene": [ { "name": "PDSS1", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TV23", "locus": { "chromosome": "13", "start_pos": 17915664, "end_pos": 17956810, "strand": "+", "evidence": [ { "database": "Ensembl Gene", "id": "ENSBTAG00000006529", "url": "https://www.ensembl.org/id/ENSBTAG00000006529" } ] } } ], "crossref": [ { "id": "A0AAA9TV23", "url": "https://alphafold.ebi.ac.uk/entry/A0AAA9TV23", "database": "AlphaFoldDB", "categories": [] }, { "id": "ENSBTAG00000006529", "url": "https://bgee.org/?page=gene&gene_id=ENSBTAG00000006529", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "cd00685", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd00685", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "509696", "url": "https://www.ncbi.nlm.nih.gov/gene/509696", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR000092", "url": "https://www.ebi.ac.uk/interpro/entry/IPR000092", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR008949", "url": "https://www.ebi.ac.uk/interpro/entry/IPR008949", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR033749", "url": "https://www.ebi.ac.uk/interpro/entry/IPR033749", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "F6RJN8", "url": "https://www.orthodb.org/?gene=F6RJN8", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR12001", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR12001", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR12001:SF69", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR12001:SF69", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00348", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00348", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "R-BTA-2142789", "url": "https://www.reactome.org/PathwayBrowser/#R-BTA-2142789", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "27802", "url": "https://www.rhea-db.org/rhea/27802", "database": "Rhea", "categories": [ "Enzyme and Pathway" ] }, { "id": "55364", "url": "https://www.rhea-db.org/rhea/55364", "database": "Rhea", "categories": [ "Enzyme and Pathway" ] }, { "id": "A0A3Q1MLA7", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1MLA7", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A3Q1MLA7-1", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1MLA7-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0AAA9TU73", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TU73", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0AAA9TU73-1", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TU73-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0AAA9TV23", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TV23", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0AAA9TV23-1", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TV23-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "F6RJN8", "url": "https://www.uniprot.org/uniprotkb/F6RJN8", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "F6RJN8-1", "url": "https://www.uniprot.org/uniprotkb/F6RJN8-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MQSYHPGPWGGSSTWHSPSPPYPPHLISLSLSPESCFYLFLVVWDLCCCTRVFLSLRQAEGLLSSCSAQATLCGDFSCRARVLGAQDPVAVVFRLRCSEACGIFPDQGSNRCPCIGRQELFISTAELREMSEYHFDGKGKAFRPIIVVLMARACNIHHNNARNVQASQRAIALIAEMIHTASLVHDDIIDDASSRRGKHTVNKIWGEKKAVLAGDLILSAASIALARIGNTTVISILTQVIEDLVRGEFLQLGSKENENERFAHYLEKTFKKTASLIANSCKAVSVLGCPDPAVHEIAYQYGKNVGIAFQLIDDVLDFTSCSEQMGKPTSADLKLGLATGPVLFACQQFPEMNAMIMRRFGSPGDVDRALQYVLQSDGVQQTTYLAQRYCHKAVSEISKLRPSPERDALIQLSEMVLTRDK", "length": 421, "header": "tr|A0AAA9TV23-1|A0AAA9TV23_BOVIN Isoform 1 of All trans-polyprenyl-diphosphate synthase PDSS1 OS=Bos taurus OX=9913 GN=PDSS1 PE=3 SV=1 CANONICAL=A0AAA9TV23-1" }, "isoforms": [ { "isoform_ac": "A0A3Q1MLA7-1", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1MLA7/entry", "sequence": { "sequence": "MASCWWPWRWRRGCSWRPAARSPGPNSAGRAALYAPRAAAVAAAATVAVARAQMSYCNLMKSLTSAFRNMYGVSRFHHTTPVACCFSETLSGEKYTDPFKIGWRDLKGLYEDIRKELFISTAELREMSEYHFDGKGKAFRPIIVVLMARACNIHHNNARNVQASQRAIALIAEMIHTASLVHDDIIDDASSRRGKHTVNKIWGEKKAVLAGDLILSAASIALARIGNTTVISILTQVIEDLVRGEFLQLGSKENENERFAHYLEKTFKKTASLIANSCKAVSVLGCPDPAVHEIAYQYGKNVGIAFQLIDDVLDFTSCSEQMGKPTSADLKLGLATGPVLFACQQFPEMNAMIMRRFGSPGDVDRALQYVLQYHRKRKRVPEKHLLLLY", "length": 389, "header": "tr|A0A3Q1MLA7-1|A0AAA9TV23_BOVIN Computationally mapped isoform of All trans-polyprenyl-diphosphate synthase PDSS1 OS=Bos taurus OX=9913 GN=PDSS1 PE=3 SV=2 CANONICAL=A0AAA9TV23-1" }, "locus": { "chromosome": "13", "start_pos": 17956799, "end_pos": 17919141, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000087090.2", "url": "https://www.ensembl.org/id/ENSBTAT00000087090.2" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000072454.2", "url": "https://www.ensembl.org/id/ENSBTAP00000072454.2" } ] } }, { "isoform_ac": "A0AAA9TU73-1", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TU73/entry", "sequence": { "sequence": "MASCWWPWRWRRGCSWRPAARSPGPNSAGRAALYAPRAAAVAAAATVAVARAQMSYCNLMKSLTSAFRNMYGVSRFHHTTPVACCFSETLSGEKYTDPFKIGWRDLKGLYEDIRKELFISTAELREMSEYHFDGKGKAFRPIIVVLMARACNIHHNNARNVQASQRAIALIAEMIHTASLVHDDIIDDASSRRGKHTVNKIWGEKKAVLAGDLILSAASIALARIGNTTVISILTQVIEDLVRGEFLQLGSKENENERFAHYLEKTFKKTASLIANSCKAVSVLGCPDPAVHEIAYQYGKNVGIAFQLIDDVLDFTSCSEQMGKPTSADLKLGLATGPVLFACQQKKHIYFPILEGVSLILPADMEGVTSEGSGALPQMDLSVVYEIKK", "length": 389, "header": "tr|A0AAA9TU73-1|A0AAA9TU73_BOVIN Computationally mapped isoform of All trans-polyprenyl-diphosphate synthase PDSS1 OS=Bos taurus OX=9913 GN=PDSS1 PE=3 SV=1 CANONICAL=A0AAA9TV23-1" }, "locus": { "chromosome": "13", "start_pos": 17956799, "end_pos": 17923555, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000131172.1", "url": "https://www.ensembl.org/id/ENSBTAT00000131172.1" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000100105.1", "url": "https://www.ensembl.org/id/ENSBTAP00000100105.1" } ] } }, { "isoform_ac": "A0AAA9TV23-1", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TV23/entry", "sequence": { "sequence": "MQSYHPGPWGGSSTWHSPSPPYPPHLISLSLSPESCFYLFLVVWDLCCCTRVFLSLRQAEGLLSSCSAQATLCGDFSCRARVLGAQDPVAVVFRLRCSEACGIFPDQGSNRCPCIGRQELFISTAELREMSEYHFDGKGKAFRPIIVVLMARACNIHHNNARNVQASQRAIALIAEMIHTASLVHDDIIDDASSRRGKHTVNKIWGEKKAVLAGDLILSAASIALARIGNTTVISILTQVIEDLVRGEFLQLGSKENENERFAHYLEKTFKKTASLIANSCKAVSVLGCPDPAVHEIAYQYGKNVGIAFQLIDDVLDFTSCSEQMGKPTSADLKLGLATGPVLFACQQFPEMNAMIMRRFGSPGDVDRALQYVLQSDGVQQTTYLAQRYCHKAVSEISKLRPSPERDALIQLSEMVLTRDK", "length": 421, "header": "tr|A0AAA9TV23-1|A0AAA9TV23_BOVIN Isoform 1 of All trans-polyprenyl-diphosphate synthase PDSS1 OS=Bos taurus OX=9913 GN=PDSS1 PE=3 SV=1 CANONICAL=A0AAA9TV23-1" }, "locus": { "chromosome": "13", "start_pos": 17947671, "end_pos": 17916668, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000120367.1", "url": "https://www.ensembl.org/id/ENSBTAT00000120367.1" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000100977.1", "url": "https://www.ensembl.org/id/ENSBTAP00000100977.1" } ] } }, { "isoform_ac": "F6RJN8-1", "url": "https://www.uniprot.org/uniprotkb/F6RJN8/entry", "sequence": { "sequence": "MASCWWPWRWRRGCSWRPAARSPGPNSAGRAALYAPRAAAVAAAATVAVARAQMSYCNLMKSLTSAFRNMYGVSRFHHTTPVACCFSETLSGEKYTDPFKIGWRDLKGLYEDIRKELFISTAELREMSEYHFDGKGKAFRPIIVVLMARACNIHHNNARNVQASQRAIALIAEMIHTASLVHDDIIDDASSRRGKHTVNKIWGEKKAVLAGDLILSAASIALARIGNTTVISILTQVIEDLVRGEFLQLGSKENENERFAHYLEKTFKKTASLIANSCKAVSVLGCPDPAVHEIAYQYGKNVGIAFQLIDDVLDFTSCSEQMGKPTSADLKLGLATGPVLFACQQSDGVQQTTYLAQRYCHKAVSEISKLRPSPERDALIQLSEMVLTRDK", "length": 391, "header": "tr|F6RJN8-1|F6RJN8_BOVIN Computationally mapped isoform of All trans-polyprenyl-diphosphate synthase PDSS1 OS=Bos taurus OX=9913 GN=PDSS1 PE=3 SV=3 CANONICAL=A0AAA9TV23-1" }, "locus": { "chromosome": "13", "start_pos": 17956799, "end_pos": 17916668, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000008576.7", "url": "https://www.ensembl.org/id/ENSBTAT00000008576.7" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000008576.7", "url": "https://www.ensembl.org/id/ENSBTAP00000008576.7" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [ "enzyme" ], "publication": [], "pathway": [ { "id": "R-BTA-2142789", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-BTA-2142789", "resource": "Reactome", "description": "Ubiquinol biosynthesis" } ], "orthologs": [], "go_annotation": { "categories": [ { "name": "Molecular Function", "total": 4, "go_terms": [ { "name": "metal ion binding", "id": "GO:0046872", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0046872", "evidence": [ { "database": "UniProtKB", "id": "A0AAA9TV23", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TV23" } ], "pmid": "" }, { "name": "all-trans-decaprenyl-diphosphate synthase activity", "id": "GO:0097269", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0097269", "evidence": [ { "database": "UniProtKB", "id": "A0AAA9TV23", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TV23" } ], "pmid": "" }, { "name": "all-trans-nonaprenyl-diphosphate synthase (geranyl-diphosphate specific) activity", "id": "GO:0052923", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0052923", "evidence": [ { "database": "UniProtKB", "id": "A0AAA9TV23", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TV23" } ], "pmid": "" }, { "name": "prenyltransferase activity", "id": "GO:0004659", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0004659", "evidence": [ { "database": "UniProtKB", "id": "A0AAA9TV23", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TV23" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 2, "go_terms": [ { "name": "ubiquinone biosynthetic process", "id": "GO:0006744", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006744", "evidence": [ { "database": "UniProtKB", "id": "A0AAA9TV23", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TV23" } ], "pmid": "" }, { "name": "isoprenoid biosynthetic process", "id": "GO:0008299", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008299", "evidence": [ { "database": "UniProtKB", "id": "A0AAA9TV23", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TV23" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 4, "go_terms": [ { "name": "heterotetrameric polyprenyl diphosphate synthase complex", "id": "GO:0032478", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0032478", "evidence": [ { "database": "UniProtKB", "id": "A0AAA9TV23", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TV23" } ], "pmid": "" }, { "name": "mitochondrial matrix", "id": "GO:0005759", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005759", "evidence": [ { "database": "UniProtKB", "id": "A0AAA9TV23", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TV23" } ], "pmid": "" }, { "name": "mitochondrion", "id": "GO:0005739", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005739", "evidence": [ { "database": "UniProtKB", "id": "A0AAA9TV23", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TV23" } ], "pmid": "" }, { "name": "polyprenyl diphosphate synthase complex", "id": "GO:0032476", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0032476", "evidence": [ { "database": "UniProtKB", "id": "A0AAA9TV23", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TV23" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 230, "end_pos": 232, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [ { "id": "27802", "name": "", "equation": "7 isopentenyl diphosphate + (2E,6E)-farnesyl diphosphate = all-trans-decaprenyl diphosphate + 7 diphosphate", "summary": "", "cellular_location": "", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [ "A0AAA9TV23-1" ], "evidence": [ { "id": "27802", "database": "Rhea", "url": "https://www.rhea-db.org/rhea/27802" } ] }, { "id": "55364", "name": "", "equation": "6 isopentenyl diphosphate + (2E,6E)-farnesyl diphosphate = all-trans-nonaprenyl diphosphate + 6 diphosphate", "summary": "", "cellular_location": "", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [ "A0AAA9TV23-1" ], "evidence": [ { "id": "55364", "database": "Rhea", "url": "https://www.rhea-db.org/rhea/55364" } ] }, { "id": "R-BTA-2162253", "name": "PDSS1,2 ligates FPP to IPPP", "equation": "", "summary": "This event has been computationally inferred from an event that has been demonstrated in another species.

The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.

More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "cellular_location": "mitochondrial matrix", "input_participant_list": [ "R-ALL-2162256", "R-ALL-2162257" ], "output_participant_list": [], "enzyme_list": [ "A0AAA9TV23-1" ], "evidence": [ { "id": "R-BTA-2162253", "database": "Reactome", "url": "https://www.reactome.org/PathwayBrowser/#R-BTA-2162253" } ] } ], "reaction_participants": [ { "participant_id": "R-ALL-2162256", "participant_name": "IPPP [mitochondrial matrix]", "crossref": [ { "id": "128769", "database": "ChEBI", "url": "" }, { "id": "C00129", "database": "COMPOUND", "url": "" }, { "id": "ZINC000008215654", "database": "ZINC", "url": "" } ] }, { "participant_id": "R-ALL-2162257", "participant_name": "FPP [mitochondrial matrix]", "crossref": [ { "id": "175763", "database": "ChEBI", "url": "" }, { "id": "ZINC000012494625", "database": "ZINC", "url": "" } ] } ], "reaction_enzymes": [ { "uniprot_ac": "A0AAA9TV23", "gene_name": "PDSS1", "activity": [ { "ec_number": "2.5.1.91", "activity": "7 isopentenyl diphosphate + (2E,6E)-farnesyl diphosphate = all-trans-decaprenyl diphosphate + 7 diphosphate.", "evidence": [ { "id": "A0AAA9TV23", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TV23" } ] }, { "ec_number": "2.5.1.91", "activity": "", "evidence": [ { "id": "A0AAA9TV23", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TV23" } ] } ] } ], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [ { "ec_number": "2.5.1.91", "ec_name": "7 isopentenyl diphosphate + (2E,6E)-farnesyl diphosphate = all-trans-decaprenyl diphosphate + 7 diphosphate.", "evidence": [ { "id": "2.5.1.91", "database": "Rhea", "url": "https://www.rhea-db.org/rhea/?query=ec:2.5.1.91" }, { "id": "2.5.1.91", "database": "BRENDA Enzymes", "url": "https://www.brenda-enzymes.org/enzyme.php?ecno=2.5.1.91" } ] } ], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 230, "end_pos": 232 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ], "tool_support": { "graph_view": "yes" } }, { "uniprot_canonical_ac": "A0AAA9TSB7-1", "uniprot_ac": "A0AAA9TSB7", "uniprot_id": "A0AAA9TSB7_BOVIN", "mass": { "chemical_mass": 19645.0, "monoisotopic_mass": 19645.0 }, "refseq": { "ac": "XP_059740501", "name": "small ribosomal subunit protein uS12 isoform X3", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_059740501" }, "gene_names": [ { "name": "LOC100336029", "type": "recommended", "evidence": [ { "id": "A0AAA9TSB7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TSB7" } ] }, { "name": "LOC100336029", "type": "synonym", "evidence": [ { "id": "XP_059740501", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_059740501" } ] } ], "protein_names": [ { "name": "Small ribosomal subunit protein uS12", "type": "recommended", "evidence": [ { "id": "A0AAA9TSB7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TSB7/entry#names_and_taxonomy" } ] }, { "name": "40S ribosomal protein S23", "type": "synonym", "evidence": [ { "id": "A0AAA9TSB7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TSB7/entry#names_and_taxonomy" } ] }, { "name": "small ribosomal subunit protein uS12 isoform X3", "type": "synonym", "evidence": [ { "id": "XP_059740501", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_059740501" } ] } ], "function": [], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Bos taurus", "taxid": 9913, "evidence": [ { "database": "UniProtKB", "id": "A0AAA9TSB7", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TSB7" } ], "common_name": "Bovine", "glygen_name": "Bovine", "reference_species": "Bos taurus [9913]" } ], "gene": [ { "name": "LOC100336029", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TSB7", "locus": {} } ], "crossref": [ { "id": "ENSBTAG00000002009", "url": "https://bgee.org/?page=gene&gene_id=ENSBTAG00000002009", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "cd03367", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd03367", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "100336029", "url": "https://www.ncbi.nlm.nih.gov/gene/100336029", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR005680", "url": "https://www.ebi.ac.uk/interpro/entry/IPR005680", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR006032", "url": "https://www.ebi.ac.uk/interpro/entry/IPR006032", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR012340", "url": "https://www.ebi.ac.uk/interpro/entry/IPR012340", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "PTHR11652", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR11652", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00164", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00164", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "XP_059740501", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_059740501", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A3Q1MLY7", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1MLY7", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A3Q1MLY7-1", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1MLY7-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0AAA9TSB7", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TSB7", "database": "UniProtKB", 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"https://www.ncbi.nlm.nih.gov/protein/XP_005219750" }, "gene_names": [ { "name": "ISOC2", "type": "recommended", "evidence": [ { "id": "A0AAA9TUB0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TUB0" } ] }, { "name": "ISOC2", "type": "synonym", "evidence": [ { "id": "XP_005219750", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_005219750" } ] } ], "protein_names": [ { "name": "Isochorismatase domain containing 2", "type": "synonym", "evidence": [ { "id": "A0AAA9TUB0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TUB0/entry#names_and_taxonomy" } ] }, { "name": "isochorismatase domain-containing protein 2 isoform X1", "type": "synonym", "evidence": [ { "id": "XP_005219750", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_005219750" } ] } ], "function": [], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Bos taurus", 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"https://www.ebi.ac.uk/interpro/entry/IPR000868", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR036380", "url": "https://www.ebi.ac.uk/interpro/entry/IPR036380", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR050993", "url": "https://www.ebi.ac.uk/interpro/entry/IPR050993", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "F1N6A0", "url": "https://www.orthodb.org/?gene=F1N6A0", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR14119", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR14119", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR14119:SF3", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR14119:SF3", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00857", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00857", "database": "Pfam", 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{}, "start_pos": 67, "start_aa": "Thr", "end_pos": 67, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr67", "evidence": [ { "id": "", "database": "GlyGen", "url": "https://data.glygen.org/" } ], "filter_code": "000000000000000010000.00000000001000.0.01000" } ], "phosphorylation": [], "glycation": [], "keywords": [ "glycoprotein", "glycoprotein_predicted" ], "publication": [], "pathway": [], "orthologs": [], "go_annotation": {}, "pro_annotation": [], "site_annotation": [], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A0AAA9TUB0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TUB0" }, { "id": "PF00857", "database": "Pfam", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00857" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "Isochorismatase-like", "eco_id": "ECO_0000259", "start_pos": 16, "end_pos": 140, "start_aa": "Ser", "end_aa": "Ser", "glycosite_overlap": [] } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [ 67, 150 ], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 2 }, { "field": "total_sites", "count": 2 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 2 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "exact_sites", "count": 2 }, { "field": "exact_o_linked_sites", "count": 2 }, { "field": "fuzzy_sites", "count": 0 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_pos", "start_aa", "end_pos", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 2 }, { "field": "total_sites", "count": 2 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 2 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "exact_sites", "count": 2 }, { "field": "exact_o_linked_sites", "count": 2 }, { "field": "fuzzy_sites", "count": 0 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_pos", "start_aa", "end_pos", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ], "tool_support": { "graph_view": "yes" } }, { "uniprot_canonical_ac": "A0AAA9TVP1-1", "uniprot_ac": "A0AAA9TVP1", "uniprot_id": "A0AAA9TVP1_BOVIN", "mass": { "chemical_mass": 200913.0, "monoisotopic_mass": 200913.0 }, "refseq": { "ac": "XP_005209947", "name": "focadhesin", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_005209947" }, "gene_names": [ { "name": "FOCAD", "type": "recommended", "evidence": [ { "id": "A0AAA9TVP1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TVP1" } ] }, { "name": "FOCAD", "type": "synonym", "evidence": [ { "id": "XP_005209947", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_005209947" } ] } ], "protein_names": [ { "name": "Focadhesin", "type": "synonym", "evidence": [ { "id": "A0AAA9TVP1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TVP1/entry#names_and_taxonomy" } ] }, { "name": "focadhesin", "type": "synonym", "evidence": [ { "id": "XP_005209947", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_005209947" } ] } ], "function": [], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Bos taurus", "taxid": 9913, "evidence": [ { "database": "UniProtKB", "id": "A0AAA9TVP1", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TVP1" } ], "common_name": "Bovine", "glygen_name": "Bovine", "reference_species": "Bos taurus [9913]" } ], "gene": [ { "name": "FOCAD", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TVP1", "locus": { "chromosome": "8", "start_pos": 23422455, "end_pos": 23725252, "strand": "+", "evidence": [ { "database": "Ensembl Gene", "id": "ENSBTAG00000038181", "url": "https://www.ensembl.org/id/ENSBTAG00000038181" } ] } } ], "crossref": [ { "id": "ENSBTAG00000038181", "url": "https://bgee.org/?page=gene&gene_id=ENSBTAG00000038181", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "506199", "url": "https://www.ncbi.nlm.nih.gov/gene/506199", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR016024", "url": "https://www.ebi.ac.uk/interpro/entry/IPR016024", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR021392", "url": "https://www.ebi.ac.uk/interpro/entry/IPR021392", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR022542", "url": "https://www.ebi.ac.uk/interpro/entry/IPR022542", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR045163", "url": "https://www.ebi.ac.uk/interpro/entry/IPR045163", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "GQLFSWF", "url": "https://omabrowser.org/oma/group/GQLFSWF/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "A0A3Q1MN26", "url": "https://www.orthodb.org/?gene=A0A3Q1MN26", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "F1MQ56", "url": "https://www.orthodb.org/?gene=F1MQ56", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR16212", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR16212", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR16212:SF4", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR16212:SF4", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF11229", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF11229", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF12530", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF12530", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "XP_005209947", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_005209947", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A3Q1MN26", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1MN26", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A3Q1MN26-1", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1MN26-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0AAA9RWE2", "url": "https://www.uniprot.org/uniprotkb/A0AAA9RWE2", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0AAA9RWE2-1", "url": "https://www.uniprot.org/uniprotkb/A0AAA9RWE2-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0AAA9SL32", "url": "https://www.uniprot.org/uniprotkb/A0AAA9SL32", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0AAA9SL32-1", "url": "https://www.uniprot.org/uniprotkb/A0AAA9SL32-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0AAA9SN38", "url": "https://www.uniprot.org/uniprotkb/A0AAA9SN38", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0AAA9SN38-1", "url": "https://www.uniprot.org/uniprotkb/A0AAA9SN38-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0AAA9TFM4", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TFM4", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0AAA9TFM4-1", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TFM4-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0AAA9TJA5", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TJA5", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0AAA9TJA5-1", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TJA5-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0AAA9TPK3", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TPK3", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0AAA9TPK3-1", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TPK3-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0AAA9TVP1", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TVP1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0AAA9TVP1-1", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TVP1-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0ABI0P1X7", "url": "https://www.uniprot.org/uniprotkb/A0ABI0P1X7", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0ABI0P1X7-1", "url": "https://www.uniprot.org/uniprotkb/A0ABI0P1X7-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "F1MQ56", "url": "https://www.uniprot.org/uniprotkb/F1MQ56", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "F1MQ56-1", "url": "https://www.uniprot.org/uniprotkb/F1MQ56-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MLDDIRKRFEFPNSLIQSQAVGHLIAAVLKENSFSEKIHQCTNQTPALNLLWEKCCSDNVVVRTACCEGLVALVAQDHAEFSYVLNGILNLIPSTRNTHGLIKALMKLLQMQAVKEGHSGEKNIQDIYNIRNHPQPLITVLEHRPDCWPVILQQLTAFFQQCLERSEVSCIQIMAPFLWYLYCEPPQLQEYAKLRLTLLKVLLKPRVPCDKEQPSILEQQILQLCCDMVPCLQIKDLIQTTEVMLFIEEVYLNLLRYPVFWKIQLTQLTLQLLCVCEVSLNITGECSSLIHLLEHSVELLKEDFPVEPVIIGIALLLLQTPASQQKPILSLALKLLSSAESQKIPKSSLLLVMPLLQILSSTALEDCISVDEEGPSRQQLAVNLLEMVQQERYRDKHRKLSYKLAFPITSMYGSIFTAWRILEVMREESAASDWLASVESLLPITTVIPAHVFLLLAYLLVEDKGRNLHQILKVTTELAQADSSQVPNLIPVLMFKLGRPLAPVLYNDILYTLPTLGVHKVCIGQILRVIQLLGTTPQLKAVTLRLLTSLWEKQDRVYPELQRFMAMSDVPSLSVGKEVQWEKLIAKAASIRDICKQRPYQHGADMLAAISQVLNECTKPDQATPAALVLQGLHALCQAEVVCIRSTWNALSPKLSCDTRPLILKTLSELFSLVPSLTVNTAEYENFKVQVLSFLWNHTQNKDPIVANAAYKSLSHFGAGDHTILHLPEEVRPEIQTPDDLDEDEDEEGDEKEVDLSIPGSCYLKLLSLTAPSVLPALEEFFTSLVKQEMVNMPRGVYHSALKGGARLDQGKTVAGIPNFMLKMYETNKQPGLKPGLAGGMLFCYDISMYQSKDGKPLNRLMASRGRSFKQTSLALVHEVHIQPSEWHRAIFLPQAWLAYMTRAYHAILQGRIGELDLQLKHGKEGPEEVQYKKNTAWLWVRDMLTDEITKAAAKDSPVVKGNALLALSSLAVVVSKHEVSLCSDSDRVLEVQPHFLSVKDWVSMIFDTLLVIVDSHYQPRGHFFSSFYHKSYSGENTASAIARSAAATALSLLVPIFIISCKEKVEEILNMLTARLPGKPRADESQAVQIHMGLALGMFLSRLCEEKLSDISSQQMNLLLMKSLDALENCCFDPSLEYNTGCILGVGLVLSLMSHSGQTESRVHVAASLRKLSAYLDDSRSQSRTFQEVLAYTISCVCTSAFSAGIIEAVEAEDIMNKLRLLVDNSQQTSGFALALGNIIHGLSVCGHGKAEDLGNRLLPAWIKTVLTEGAPTMLCLAALHGMVALVGSEGDVMQLKSEAIQSSQSQGRLNEVIRTLTQVISVSGVIGLQSNAIWLLGHLHLSTLSSNQSRTSVPTDYSYLPENSFIRAAIGFFVTGGKKGPESVPPSLLKVVMKPIATVGENHQYPPVNWAALLSPLMRLNFGEEIQQLCLEIMVTQAQSSQNVTTLLGMWVMPPLIHGLSLNIKKYLLLSVPSWIKHVSDEQIVGFVESLMVAVFKAASPLSSPELRPSALQGLSQAMKLPSPSHHLWSLLSEATRKIFDLLPNKIRRNDLELYISVAKCLSEMTDDEADRVAQITESSLEKAAFVRLYLVSQGRFPLMGLTDVLSVAVQHREKDTLAWMTLHSLYQARIVSHANTGVLKRMEWLLELMGYIRNVAYQSTSVQNVALDEALDFLLLIFAAAVVAWADHAAPLLLGLSASWLPWHQENGPAGPASSLLGRSPLHRVTLQEAVTLLPSSMPLLLQKEPWKEQTQKFIDWLFSIMESPKEGLSAKSKDLLKATLLSLRVLPEFKKKAVWTRAYGW", "length": 1805, "header": "tr|A0AAA9TVP1-1|A0AAA9TVP1_BOVIN Isoform 1 of Focadhesin OS=Bos taurus OX=9913 GN=FOCAD PE=4 SV=1 CANONICAL=A0AAA9TVP1-1" }, "isoforms": [ { "isoform_ac": "A0A3Q1MN26-1", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1MN26/entry", "sequence": { "sequence": "MVTAPRRSRRRGGPRQAAGVGLSLWQKGEFCLYVREVKMLDDIRKRFEFPNSLIQSQELKLFIGPQFCYYLFNKEAVGHLIAAVLKENSFSEKIHQCTNQTPALNLLWEKCCSDNVVVRTACCEGLVALVAQDHAEFSYVLNGILNLIPSTRNTHGLIKALMKLLQMQAVKEGHSGEKNIQDIYNIRNHPQPLITVLEHRPDCWPVILQQLTAFFQQCLERSEVSCIQIMAPFLWYLYCEPPQLQEYAKLRLTLLKVLLKPRVPCDKEQPSILEQQILQLCCDMVPCLQIKDLIQTTEVMLFIEEVYLNLLRYPVFWKIQLTQLTLQLLCVCEVSLNITGECSSLIHLLEHSVELLKEDFPVEPVIIGIALLLLQTPASQQKPILSLALKLLSSAESQKIPKSSLLLVMPLLQILSSTALEDCISVDEEGPSRQQLAVNLLEMVQQERYRDKHRKLSYKLAFPITSMYGSIFTAWRILEVMREESAASDWLASVESLLPITTVIPAHVFLLLAYLLVEDKGRNLHQILKVTTELAQADSSQVPNLIPVLMFKLGRPLAPVLYNDILYTLPTLGVHKVCIGQILRVIQLLGTTPQLKAVTLRLLTSLWEKQDRVYPELQRFMAMSDVPSLSVGKEVQWEKLIAKAASIRDICKQRPYQHGADMLAAISQVLNECTKPDQATPAALVLQGLHALCQAEVVCIRSTWNALSPKLSCDTRPLILKTLSELFSLVPSLTVNTAEYENFKVQVLSFLWNHTQNKDPIVANAAYKSLSHFGAGDHTILHLPEEVRPEIQTPDDLDEDEDEEGDEKEVDLSIPGSCYLKLLSLTAPSVLPALEEFFTSLVKQEMVNMPRGVYHSALKGGARLDQGKTVAGIPNFMLKMYETNKQPGLKPGLAGGMLFCYDISMYQSKDGKPLNRLMASRGRSFKQTSLALVHEVHIQPSEWHRAIFLPQAWLAYMTRAYHAILQGRIGELDLQLKHGKEGPEEVQYKKNTAWLWVRDMLTDEITKAAAKDSPVVKGNALLALSSLAVVVSKHEVSLCSDSDRVLEVQPHFLSVKDWVSMIFDTLLVIVDSHYQPRGHFFSSFYHKSYSGENTASAIARSAAATALSLLVPIFIISCKEKVEEILNMLTARLPGKPRADESQAVQIHMGLALGMFLSRLCEEKLSDISSQQMNLLLMKSLDALENCCFDPSLEYNTGCILGVGLVLSLMSHSGQTESRVHVAASLRKLSAYLDDSRSQSRTFQEVLAYTISCVCTSAFSAGIIEAVEAEDIMNKLRLLVDNSQQTSGFALALGNIIHGLSVCGHGKAEDLGNRLLPAWIKTVLTEGAPTMLCLAALHGMVALVGSEGDVMQLKSEAIQSSQSQGRLNEVIRTLTQVISVSGVIGLQSNAIWLLGHLHLSTLSSNQSRTSVPTDYSYLPENSFIRAAIGFFVTGGKKGPESVPPSLLKVVMKPIATVGENHQYPPVNWAALLSPLMRLNFGEEIQQLCLEIMVTQAQSSQNVTTLLGMWVMPPLIHGLSLNIKKYLLLSVPSWIKHVSDEQIVGFVESLMVAVFKAASPLSSPELRPSALQGLSQAMKLPSPSHHLWSLLSEATRKIFDLLPNKIRRNDLELYISVAKCLSEMTDDEADRVAQITESSLEKAAFVRLYLVSQGRFPLMGLTDVLSVAVQHREKDTLAWMTLHSLYQARIVSHANTGVLKRMEWLLELMGYIRNVAYQSTSVQNVALDEALDFLLLIFAAAVVAWADHAAPLLLGLSASWLPWHQENGPAGPASSLLGRSPLHRVTLQEAVTLLPSSMPLLLQKEPWKEQTQKFIDWLFSIMESPKEGLSAKSKDLLKATLLSLRVLPEFKKKAVWTRAYGW", "length": 1861, "header": "tr|A0A3Q1MN26-1|A0AAA9TVP1_BOVIN Computationally mapped isoform of Focadhesin OS=Bos taurus OX=9913 GN=FOCAD PE=4 SV=2 CANONICAL=A0AAA9TVP1-1" }, "locus": { "chromosome": "8", "start_pos": 23725237, "end_pos": 23422763, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000070536.2", "url": "https://www.ensembl.org/id/ENSBTAT00000070536.2" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000073265.2", "url": "https://www.ensembl.org/id/ENSBTAP00000073265.2" } ] } }, { "isoform_ac": "A0AAA9RWE2-1", "url": "https://www.uniprot.org/uniprotkb/A0AAA9RWE2/entry", "sequence": { "sequence": "MAIYVPTKFFFPLEEVSILAFPKTHFGYFCYDVLWNNREEHFKKEFCLYVREVKMLDDIRKRFEFPNSLIQSQAVGHLIAAVLKENSFSEKIHQCTNQTPALNLLWEKCCSDNVVVRTACCEGLVALVAQDHAEFSYVLNGILNLIPSTRNTHGLIKALMKLLQMQAVKEGHSGEKNIQDIYNIRNHPQPLITVLEHRPDCWPVILQQLTAFFQQCLERSEVSCIQIMAPFLWYLYCEPPQLQEYAKLRLTLLKVLLKPRVPCDKEQPSILEQQILQLCCDMVPCLQIKDLIQTTEVMLFIEEVYLNLLRYPVFWKIQLTQLTLQLLCVCEVSLNITGECSSLIHLLEHSVELLKEDFPVEPVIIGIALLLLQTPASQQKPILSLALKLLSSAESQKIPKSSLLLVMPLLQILSSTALEDCISVDEEGPSRQQLAVNLLEMVQQERYRDKHRKLSYKLAFPITSMYGSIFTAWRILEVMREESAASDWLASVESLLPITTVIPAHVFLLLAYLLVEDKGRNLHQILKVTTELAQADSSQVPNLIPVLMFKLGRPLAPVLYNDILYTLPTLGVHKVCIGQILRVIQLLGTTPQLKAVTLRLLTSLWEKQDRVYPELQRFMAMSDVPSLSVGKEVQWEKLIAKAASIRDICKQRPYQHGADMLAAISQVLNECTKPDQATPAALVLQGLHALCQAEVVCIRSTWNALSPKLSCDTRPLILKTLSELFSLVPSLTVNTAEYENFKVQVLSFLWNHTQNKDPIVANAAYKSLSHFGAGDHTILHLPEEVRPEIQTPDDLDEDEDEEGDEKEVDLSIPGSCYLKLLSLTAPSVLPALEEFFTSLVKQEMVNMPRGVYHSALKGGARLDQGKTVAGIPNFMLKMYETNKQPGLKPGLAGGMLFCYDISMYQSKDGKPLNRLMASRGRSFKQTSLALVHEVHIQPSEWHRAIFLPQAWLAYMTRAYHAILQGRIGELDLQLKHGKEGPEEVQYKKNTAWLWVRDMLTDEITKAAAKDSPVVKGNALLALSSLAVVVSKHEVSLCSDSDRVLEVQPHFLSVKDWVSMIFDTLLVIVDSHYQPRGHFFSSFYHKSYSGENTASAIARSAAATALSLLVPIFIISCKEKVEEILNMLTARLPGKPRADESQAVQIHMGLALGMFLSRLCEEKLSDISSQQMNLLLMKSLDALENCCFDPSLEYNTGCILGVGLVLSLMSHSGQTESRVHVAASLRKLSAYLDDSRSQSRTFQEVLAYTISCVCTSAFSAGIIEAVEAEDIMNKLRLLVDNSQQTSGFALALGNIIHGLSVCGHGKAEDLGNRLLPAWIKTVLTEGAPTMLCLAALHGMVALVGSEGDVMQLKSEAIQSSQSQGRLNEVIRTLTQVISVSGVIGLQSNAIWLLGHLHLSTLSSNQSRTSVPTDYSYLPENSFIRAAIGFFVTGGKKGPESVPPSLLKVVMKPIATVGENHQYPPVNWAALLSPLMRLNFGEEIQQLCLEIMVTQAQSSQNVTTLLGMWVMPPLIHGLSLNIKKYLLLSVPSWIKHVSDEQIVGFVESLMVAVFKAASPLSSPELRPSALQGLSQAMKLPSPSHHLWSLLSEATRKIFDLLPNKIRRNDLELYISVAKCLSEMTDDEADRVAQITESSLEKAAFVRLYLVSQGRFPLMGLTDVLSVAVQHREKDTLAWMTLHSLYQARIVSHANTGVLKRMEWLLELMGYIRNVAYQSTSVQNVALDEALDFLLLIFAAAVVAWADHAAPLLLGLSASWLPWHQENGPAGPASSLLGRSPLHRVTLQEAVTLLPSSMPLLLQKEPWKEQTQKFIDWLFSIMESPKEGLSAKSKDLLKATLLSLRVLPEFKKKAVWTRAYGW", "length": 1859, "header": "tr|A0AAA9RWE2-1|A0AAA9TVP1_BOVIN Computationally mapped isoform of Focadhesin OS=Bos taurus OX=9913 GN=FOCAD PE=4 SV=1 CANONICAL=A0AAA9TVP1-1" }, "locus": { "chromosome": "8", "start_pos": 23700704, "end_pos": 23422763, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000117684.1", "url": "https://www.ensembl.org/id/ENSBTAT00000117684.1" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000077749.1", "url": "https://www.ensembl.org/id/ENSBTAP00000077749.1" } ] } }, { "isoform_ac": "A0AAA9SL32-1", "url": "https://www.uniprot.org/uniprotkb/A0AAA9SL32/entry", "sequence": { "sequence": "MLDDIRKRFEFPNSLIQSQAVGHLIAAVLKENSFSEKIHQCTNQTPALNLLWEKCCSDNVVVRTACCEGLVALVAQDHAEFSYVLNGILNLIPSTRNTHGLIKALMKLLQMQAVKEGHSGEKNIQDIYNIRNHPQPLITVLEHRPDCWPVILQQLTAFFQQCLERSEVSCIQIMAPFLWYLYCEPPQLQEYAKLRLTLLKVLLKPRVPCDKEQPSILEQQILQLCCDMVPCLQIKDLIQTTEVMLFIEEVYLNLLRYPVFWKIQLTQLTLQLLCVCEVSLNITGECSSLIHLLEHSVELLKEDFPVEPVIIGIALLLLQTPASQQKPILSLAWRILEVMREESAASDWLASVESLLPITTVIPAHVFLLLAYLLVEDKGRNLHQILKVTTELAQADSSQVPNLIPVLMFKLGRPLAPVLYNDILYTLPTLGVHKVCIGQILRVIQLLGTTPQLKAVTLRLLTSLWEKQDRVYPELQRFMAMSDVPSLSVGKEVQWEKLIAKAASIRDICKQRPYQHGADMLAAISQVLNECTKPDQATPAALVLQGLHALCQAEVVCIRSTWNALSPKLSCDTRPLILKTLSELFSLVPSLTVNTAEYENFKVQVLSFLWNHTQNKDPIVANAAYKSLSHFGAGDHTILHLPEEVRPEIQTPDDLDEDEDEEGDEKEVDLSIPGSCYLKLLSLTAPSVLPALEEFFTSLVKQEMVNMPRGVYHSALKGGARLDQGKTVAGIPNFMLKMYETNKQPGLKPGLAGGMLFCYDISMYQSKDGKPLNRLMASRGRSFKQTSLALVHEVHIQPSEWHRAIFLPQAWLAYMTRAYHAILQGRIGELDLQLKHGKEGPEEVQYKKNTAWLWVRDMLTDEITKAAAKDSPVVKGNALLALSSLAVVVSKHEVSLCSDSDRVLEVQPHFLSVKDWVSMIFDTLLVIVDSHYQPRGHFFSSFYHKSYSGENTASAIARSAAATALSLLVPIFIISCKEKVEEILNMLTARLPGKPRADESQAVQIHMGLALGMFLSRLCEEKLSDISSQQMNLLLMKSLDALENCCFDPSLEYNTGCILGVGLVLSLMSHSGQTESRVHVAASLRKLSAYLDDSRSQSRTFQEVLAYTISCVCTSAFSAGIIEAVEAEDIMNKLRLLVDNSQQTSGFALALGNIIHGLSVCGHGKAEDLGNRLLPAWIKTVLTEGAPTMLCLAALHGMVALVGSEGDVMQLKSEAIQSSQSQGRLNEVIRTLTQVISVSGVIGLQSNAIWLLGHLHLSTLSSNQSRTSVPTDYSYLPENSFIRAAIGFFVTGGKKGPESVPPSLLKVVMKPIATVGENHQYPPVNWAALLSPLMRLNFGEEIQQLCLEIMVTQAQSSQNVTTLLGMWVMPPLIHGLSLNIKKYLLLSVPSWIKHVSDEQIVGFVESLMVAVFKAASPLSSPELRPSALQGLSQAMKLPSPSHHLWSLLSEATRKIFDLLPNKIRRNDLELYISVAKCLSEMTDDEADRVAQITESSLEKAAFVRLYLVSQGRFPLMGLTDVLSVAVQHREKDTLAWMTLHSLYQARIVSHANTGVLKRMEWLLELMGYIRNVAYQSTSVQNVALDEALDFLLLIFAAAVVAWADHAAPLLLGLSASWLPWHQENGPAGPASSLLGRSPLHRVTLQEAVTLLPSSMPLLLQKEPWKEQTQKFIDWLFSIMESPKEGLSAKSKDLLKATLLSLRVLPEFKKKAVWTRAYGW", "length": 1719, "header": "tr|A0AAA9SL32-1|A0AAA9TVP1_BOVIN Computationally mapped isoform of Focadhesin OS=Bos taurus OX=9913 GN=FOCAD PE=4 SV=1 CANONICAL=A0AAA9TVP1-1" }, "locus": { "chromosome": "8", "start_pos": 23699405, "end_pos": 23422763, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000132378.1", "url": "https://www.ensembl.org/id/ENSBTAT00000132378.1" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000085991.1", "url": "https://www.ensembl.org/id/ENSBTAP00000085991.1" } ] } }, { "isoform_ac": "A0AAA9SN38-1", "url": "https://www.uniprot.org/uniprotkb/A0AAA9SN38/entry", "sequence": { "sequence": "MLDDIRKRFEFPNSLIQSQAVGHLIAAVLKENSFSEKIHQCTNQTPALNLLWEKCCSDNVVVRTACCEGLVALVAQDHAEFSYVLNGILNLIPSTRNHPQPLITVLEHRPDCWPVILQQLTAFFQQCLERSEVSCIQIMAPFLWYLYCEPPQLQEYAKLRLTLLKVLLKPRVPCDKEQPSILEQQILQLCCDMVPCLQIKDLIQTTEVMLFIEEVYLNLLRYPVFWKIQLTQLTLQLLCVCEVSLNITGECSSLIHLLEHSVELLKEDFPVEPVIIGIALLLLQTPASQQKPILSLALKLLSSAESQKIPKSSLLLVMPLLQILSSTALEDCISVDEEGPSRQQLAVNLLEMVQQERYRDKHRKLSYKLAFPITSMYGSIFTAWRILEVMREESAASDWLASVESLLPITTVIPAHVFLLLAYLLVEDKGRNLHQILKVTTELAQADSSQVPNLIPVLMFKLGRPLAPVLYNDILYTLPTLGVHKVCIGQILRVIQLLGTTPQLKAVTLRLLTSLWEKQDRVYPELQRFMAMSDVPSLSVGKEVQWEKLIAKAASIRDICKQRPYQHGADMLAAISQVLNECTKPDQATPAALVLQGLHALCQAEVVCIRSTWNALSPKLSCDTRPLILKTLSELFSLVPSLTVNTAEYENFKVQVLSFLWNHTQNKDPIVANAAYKSLSHFGAGDHTILHLPEEVRPEIQTPDDLDEDEDEEGDEKEVDLSIPGSCYLKLLSLTAPSVLPALEEFFTSLVKQEMVNMPRGVYHSALKGGARLDQGKTVAGIPNFMLKMYETNKQPGLKPGLAGGMLFCYDISMYQSKDGKPLNRLMASRGRSFKQTSLALVHEVHIQPSEWHRAIFLPQAWLAYMTRAYHAILQGRIGELDLQLKHGKEGPEEVQYKKNTAWLWVRDMLTDEITKAAAKDSPVVKGNALLALSSLAVVVSKHEVSLCSDSDRVLEVQPHFLSVKDWVSMIFDTLLVIVDSHYQPRGHFFSSFYHKSYSGENTASAIARSAAATALSLLVPIFIISCKEKVEEILNMLTARLPGKPRADESQAVQIHMGLALGMFLSRLCEEKLSDISSQQMNLLLMKSLDALENCCFDPSLEYNTGCILGVGLVLSLMSHSGQTESRVHVAASLRKLSAYLDDSRSQSRTFQEVLAYTISCVCTSAFSAGIIEAVEAEDIMNKLRLLVDNSQQTSGFALALGNIIHGLSVCGHGKAEDLGNRLLPAWIKTVLTEGAPTMLCLAALHGMVALVGSEGDVMQLKSEAIQSSQSQGRLNEVIRTLTQVISVSGVIGLQSNAIWLLGHLHLSTLSSNQSRTSVPTDYSYLPENSFIRAAIGFFVTGGKKGPESVPPSLLKVVMKPIATVGENHQYPPVNWAALLSPLMRLNFGEEIQQLCLEIMVTQAQSSQNVTTLLGMWVMPPLIHGLSLNIKKYLLLSVPSWIKHVSDEQIVGFVESLMVAVFKAASPLSSPELRPSALQGLSQAMKLPSPSHHLWSLLSEATRKIFDLLPNKIRRNDLELYISVAKCLSEMTDDEADRVAQITESSLEKAAFVRLYLVSQGRFPLMGLTDVLSVAVQHREKDTLAWMTLHSLYQARIVSHANTGVLKRMEWLLELMGYIRNVAYQSTSVQNVALDEALDFLLLIFAAAVVAWADHAAPLLLGLSASWLPWHQENGPAGPASSLLGRSPLHRVTLQEAVTLLPSSMPLLLQKEPWKEQTQKFIDWLFSIMESPKEGLSAKSKDLLKATLLSLRVLPEFKKKAVWTRAYGW", "length": 1770, "header": "tr|A0AAA9SN38-1|A0AAA9TVP1_BOVIN Computationally mapped isoform of Focadhesin OS=Bos taurus OX=9913 GN=FOCAD PE=4 SV=1 CANONICAL=A0AAA9TVP1-1" }, "locus": { "chromosome": "8", "start_pos": 23699405, "end_pos": 23422763, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000111773.1", "url": "https://www.ensembl.org/id/ENSBTAT00000111773.1" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000086734.1", "url": "https://www.ensembl.org/id/ENSBTAP00000086734.1" } ] } }, { "isoform_ac": "A0AAA9TFM4-1", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TFM4/entry", "sequence": { "sequence": "MLDDIRKRFEFPNSLIQSQAVGHLIAAVLKENSFSEKIHQCTNQTPALNLLWEKCCSDNVVVRTACCEGLVALVAQDHAEFSYVLNGILNLIPSTRNTHGLIKALMKLLQMQAVKEGHSGEKNIQDIYNIRNHPQPLITVLEHRPDCWPVILQQLTAFFQQCLERSEVSCIQIMAPFLWYLYCEPPQLQEYAKLRLTLLKVLLKPRVPCDKEQPSILEQQILQLCCDMVPCLQIKDLIQTTEVMLFIEEVYLNLLRYPVFWKIQLTQLTLQLLCVCEVSLNITGECSSLIHLLEHSVELLKEDFPVEPVIIGIALLLLQTPASQQKPILSLALKLLSSAESQKIPKSSLLLVMPLLQILSSTALEDCISVDEEGPSRQQLAVNLLEMVQQERYRDKHRKLSYKLAFPITSMYGSIFTAWRILEVMREESAASDWLASVESLLPITTVIPAHVFLLLAYLLVEDKGRNLHQILKVTTELAQADSSQVPNLIPVLMFKLGRPLAPVLYNDILYTLPTLGVHKVCIGQILRVIQLLGTTPQLKAVTLRLLTSLWEKQDRVYPELQRFMAMSDVPSLSVGKEVQWEKLIAKAASIRDICKQRPYQHGADMLAAISQVLNECTKPDQATPAALVLQGLHALCQAEVVCIRSTWNALSPKLSCDTRPLILKTLSELFSLVPSLTVNTAEYENFKVQVLSFLWNHTQNKDPIVANAAYKSLSHFGAGDHTILHLPEEVRPEIQTPDDLDEDEDEEGDEKEVDLSIPGSCYLKLLSLTAPSVLPALEEFFTSLVKQEMVNMPRGVYHSALKGGARLDQGKTVAGIPNFMLKMYETNKQPGLKPGLAGGMLFCYDISMYQSKDGKPLNRLMASRGRSFKQTSLALVHEVHIQPSEWHRAIFLPQAWLAYMTRAYHAILQGRIGELDLQLKHGKEGPEEVQYKKNTAWLWVRDMLTDEITKAAAKDSPVVKGNALLALSSLAVVVSKHEVSLCSDSDRVLEVQPHFLSVKDWVSMIFDTLLVIVDSHYQPRGHFFSSFYHKSYSGENTASAIARSAAATALSLLVPIFIISCKEKVEEILNMLTARLPGKPRADESQAVQIHMGLALGMFLSRLCEEKLSDISSQQMNLLLMKSLDALENCCFDPSLEYNTGCILGVGLVLSLMSHSGQTESRVHVAASLRKLSAYLDDSRSQSRTFQEVLAYTISCVCTSAFSAGIIEAVEAEDIMNKLRLLVDNSQQTSGFALALGNIIHGLSVCGHGKAEDLGNRLLPAWIKTVLTEGAPTMLCLAALHGMVALVGSEGDVMQLKSEAIQSSQSQGRLNEVIRTLTQVISVSGVIGLQSNAIWLLGHLHLSTLSSNQSRTSVPTDYSYLPENSFIRAAIGFFVTGGKKGPESVPPSLLKVVMKPIATVGENHQYPPVNWAALLSPLMRLNFGEEIQQLCLEIMVTQAQSSQNVTTLLGMWVMPPLIHGLSLNIKKYLLLSVPSWIKHVSDEQIVGFVESLMVAVFKAASPLSSPELRPSALQGLSQAMKLPSPSHHLWSLLSEATRKIFDLLPNKIRRNDLELYISVAKCLSEMTDDEADRVAQITESSLEKAAFVRLYLVSQGRFPLMGLTDVLSVAVQHREKDTLAWMTLHSLYQARIVSHANTGVLKRMEWLLELMGYIRNVAYQSTSVQNVALDEFIDWLFSIMESPKEGLSAKSKDLLKATLLSLRVLPEFKKKAVWTRAYGW", "length": 1721, "header": "tr|A0AAA9TFM4-1|A0AAA9TVP1_BOVIN Computationally mapped isoform of Focadhesin OS=Bos taurus OX=9913 GN=FOCAD PE=4 SV=1 CANONICAL=A0AAA9TVP1-1" }, "locus": { "chromosome": "8", "start_pos": 23699405, "end_pos": 23422763, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000093693.1", "url": "https://www.ensembl.org/id/ENSBTAT00000093693.1" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000095804.1", "url": "https://www.ensembl.org/id/ENSBTAP00000095804.1" } ] } }, { "isoform_ac": "A0AAA9TJA5-1", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TJA5/entry", "sequence": { "sequence": "MLSSIIAISHSSVQHFFEFCLYVREVKMLDDIRKRFEFPNSLIQSQAVGHLIAAVLKENSFSEKIHQCTNQTPALNLLWEKCCSDNVVVRTACCEGLVALVAQDHAEFSYVLNGILNLIPSTRNTHGLIKALMKLLQMQAVKEGHSGEKNIQDIYNIRNHPQPLITVLEHRPDCWPVILQQLTAFFQQCLERSEVSCIQIMAPFLWYLYCEPPQLQEYAKLRLTLLKVLLKPRVPCDKEQPSILEQQILQLCCDMVPCLQIKDLIQTTEVMLFIEEVYLNLLRYPVFWKIQLTQLTLQLLCVCEVSLNITGECSSLIHLLEHSVELLKEDFPVEPVIIGIALLLLQTPASQQKPILSLALKLLSSAESQKIPKSSLLLVMPLLQILSSTALEDCISVDEEGPSRQQLAVNLLEMVQQERYRDKHRKLSYKLAFPITSMYGSIFTAWRILEVMREESAASDWLASVESLLPITTVIPAHVFLLLAYLLVEDKGRNLHQILKVTTELAQADSSQVPNLIPVLMFKLGRPLAPVLYNDILYTLPTLGVHKVCIGQILRVIQLLGTTPQLKAVTLRLLTSLWEKQDRVYPELQRFMAMSDVPSLSVGKEVQWEKLIAKAASIRDICKQRPYQHGADMLAAISQVLNECTKPDQATPAALVLQGLHALCQAEVVCIRSTWNALSPKLSCDTRPLILKTLSELFSLVPSLTVNTAEYENFKVQVLSFLWNHTQNKDPIVANAAYKSLSHFGAGDHTILHLPEEVRPEIQTPDDLDEDEDEEGDEKEVDLSIPGSCYLKLLSLTAPSVLPALEEFFTSLVKQEMVNMPRGVYHSALKGGARLDQGKTVAGIPNFMLKMYETNKQPGLKPGLAGGMLFCYDISMYQSKDGKPLNRLMASRGRSFKQTSLALVHEVHIQPSEWHRAIFLPQAWLAYMTRAYHAILQGRIGELDLQLKHGKEGPEEVQYKKNTAWLWVRDMLTDEITKAAAKDSPVVKGNALLALSSLAVVVSKHEVSLCSDSDRVLEVQPHFLSVKDWVSMIFDTLLVIVDSHYQPRGHFFSSFYHKSYSGENTASAIARSAAATALSLLVPIFIISCKEKVEEILNMLTARLPGKPRADESQAVQIHMGLALGMFLSRLCEEKLSDISSQQMNLLLMKSLDALENCCFDPSLEYNTGCILGVGLVLSLMSHSGQTESRVHVAASLRKLSAYLDDSRSQSRTFQEVLAYTISCVCTSAFSAGIIEAVEAEDIMNKLRLLVDNSQQTSGFALALGNIIHGLSVCGHGKAEDLGNRLLPAWIKTVLTEGAPTMLCLAALHGMVALVGSEGDVMQLKSEAIQSSQSQGRLNEVIRTLTQVISVSGVIGLQSNAIWLLGHLHLSTLSSNQSRTSVPTDYSYLPENSFIRAAIGFFVTGGKKGPESVPPSLLKVVMKPIATVGENHQYPPVNWAALLSPLMRLNFGEEIQQLCLEIMVTQAQSSQNVTTLLGMWVMPPLIHGLSLNIKKYLLLSVPSWIKHVSDEQIVGFVESLMVAVFKAASPLSSPELRPSALQGLSQAMKLPSPSHHLWSLLSEATRKIFDLLPNKIRRNDLELYISVAKCLSEMTDDEADRVAQITESSLEKAAFVRLYLVSQGRFPLMGLTDVLSVAVQHREKDTLAWMTLHSLYQARIVSHANTGVLKRMEWLLELMGYIRNVAYQSTSVQNVALDEALDFLLLIFAAAVVAWADHAAPLLLGLSASWLPWHQENGPAGPASSLLGRSPLHRVTLQEAVTLLPSSMPLLLQKEPWKEQTQKFIDWLFSIMESPKEGLSAKSKDLLKATLLSLRVLPEFKKKAVWTRAYGW", "length": 1832, "header": "tr|A0AAA9TJA5-1|A0AAA9TVP1_BOVIN Computationally mapped isoform of Focadhesin OS=Bos taurus OX=9913 GN=FOCAD PE=4 SV=1 CANONICAL=A0AAA9TVP1-1" }, "locus": { "chromosome": "8", "start_pos": 23724369, "end_pos": 23422763, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000127197.1", "url": "https://www.ensembl.org/id/ENSBTAT00000127197.1" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000096317.1", "url": "https://www.ensembl.org/id/ENSBTAP00000096317.1" } ] } }, { "isoform_ac": "A0AAA9TPK3-1", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TPK3/entry", "sequence": { "sequence": "MAETQERNHPQPLITVLEHRPDCWPVILQQLTAFFQQCLERSEVSCIQIMAPFLWYLYCEPPQLQEYAKLRLTLLKVLLKPRVPCDKEQPSILEQQILQLCCDMVPCLQIKDLIQTTEVMLFIEEVYLNLLRYPVFWKIQLTQLTLQLLCVCEVSLNITGECSSLIHLLEHSVELLKEDFPVEPVIIGIALLLLQTPASQQKPILSLALKLLSSAESQKIPKSSLLLVMPLLQILSSTALEDCISVDEEGPSRQQLAVNLLEMVQQERYRDKHRKLSYKLAFPITSMYGSIFTAWRILEVMREESAASDWLASVESLLPITTVIPAHVFLLLAYLLVEDKGRNLHQILKVTTELAQADSSQVPNLIPVLMFKLGRPLAPVLYNDILYTLPTLGVHKVCIGQILRVIQLLGTTPQLKAVTLRLLTSLWEKQDRVYPELQRFMAMSDVPSLSVGKEVQWEKLIAKAASIRDICKQRPYQHGADMLAAISQVLNECTKPDQATPAALVLQGLHALCQAEVVCIRSTWNALSPKLSCDTRPLILKTLSELFSLVPSLTVNTAEYENFKVQVLSFLWNHTQNKDPIVANAAYKSLSHFGAGDHTILHLPEEVRPEIQTPDDLDEDEDEEGDEKEVDLSIPGSCYLKLLSLTAPSVLPALEEFFTSLVKQEMVNMPRGVYHSALKGGARLDQGKTVAGIPNFMLKMYETNKQPGLKPGLAGGMLFCYDISMYQSKDGKPLNRLMASRGRSFKQTSLALVHEVHIQPSEWHRAIFLPQAWLAYMTRAYHAILQGRIGELDLQLKHGKEGPEEVQYKKNTAWLWVRDMLTDEITKAAAKDSPVVKGNALLALSSLAVVVSKHEVSLCSDSDRVLEVQPHFLSVKDWVSMIFDTLLVIVDSHYQPRGHFFSSFYHKSYSGENTASAIARSAAATALSLLVPIFIISCKEKVEEILNMLTARLPGKPRADESQAVQIHMGLALGMFLSRLCEEKLSDISSQQMNLLLMKSLDALENCCFDPSLEYNTGCILGVGLVLSLMSHSGQTESRVHVAASLRKLSAYLDDSRSQSRTFQEVLAYTISCVCTSAFSAGIIEAVEAEDIMNKLRLLVDNSQQTSGFALALGNIIHGLSVCGHGKAEDLGNRLLPAWIKTVLTEGAPTMLCLAALHGMVALVGSEGDVMQLKSEAIQSSQSQGRLNEVIRTLTQVISVSGVIGLQSNAIWLLGHLHLSTLSSNQSRTSVPTDYSYLPENSFIRAAIGFFVTGGKKGPESVPPSLLKVVMKPIATVGENHQYPPVNWAALLSPLMRLNFGEEIQQLCLEIMVTQAQSSQNVTTLLGMWVMPPLIHGLSLNIKKYLLLSVPSWIKHVSDEQIVGFVESLMVAVFKAASPLSSPELRPSALQGLSQAMKLPSPSHHLWSLLSEATRKIFDLLPNKIRRNDLELYISVAKCLSEMTDDEADRVAQITESSLEKAAFVRLYLVSQGRFPLMGLTDVLSVAVQHREKDTLAWMTLHSLYQARIVSHANTGVLKRMEWLLELMGYIRNVAYQSTSVQNVALDEALDFLLLIFAAAVVAWADHAAPLLLGLSASWLPWHQENGPAGPASSLLGRSPLHRVTLQEAVTLLPSSMPLLLQKEPWKEQTQKFIDWLFSIMESPKEGLSAKSKDLLKATLLSLRVLPEFKKKAVWTRAYGW", "length": 1681, "header": "tr|A0AAA9TPK3-1|A0AAA9TVP1_BOVIN Computationally mapped isoform of Focadhesin OS=Bos taurus OX=9913 GN=FOCAD PE=4 SV=1 CANONICAL=A0AAA9TVP1-1" }, "locus": { "chromosome": "8", "start_pos": 23667761, "end_pos": 23422763, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000104789.1", "url": "https://www.ensembl.org/id/ENSBTAT00000104789.1" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000100477.1", "url": "https://www.ensembl.org/id/ENSBTAP00000100477.1" } ] } }, { "isoform_ac": "A0AAA9TVP1-1", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TVP1/entry", "sequence": { "sequence": "MLDDIRKRFEFPNSLIQSQAVGHLIAAVLKENSFSEKIHQCTNQTPALNLLWEKCCSDNVVVRTACCEGLVALVAQDHAEFSYVLNGILNLIPSTRNTHGLIKALMKLLQMQAVKEGHSGEKNIQDIYNIRNHPQPLITVLEHRPDCWPVILQQLTAFFQQCLERSEVSCIQIMAPFLWYLYCEPPQLQEYAKLRLTLLKVLLKPRVPCDKEQPSILEQQILQLCCDMVPCLQIKDLIQTTEVMLFIEEVYLNLLRYPVFWKIQLTQLTLQLLCVCEVSLNITGECSSLIHLLEHSVELLKEDFPVEPVIIGIALLLLQTPASQQKPILSLALKLLSSAESQKIPKSSLLLVMPLLQILSSTALEDCISVDEEGPSRQQLAVNLLEMVQQERYRDKHRKLSYKLAFPITSMYGSIFTAWRILEVMREESAASDWLASVESLLPITTVIPAHVFLLLAYLLVEDKGRNLHQILKVTTELAQADSSQVPNLIPVLMFKLGRPLAPVLYNDILYTLPTLGVHKVCIGQILRVIQLLGTTPQLKAVTLRLLTSLWEKQDRVYPELQRFMAMSDVPSLSVGKEVQWEKLIAKAASIRDICKQRPYQHGADMLAAISQVLNECTKPDQATPAALVLQGLHALCQAEVVCIRSTWNALSPKLSCDTRPLILKTLSELFSLVPSLTVNTAEYENFKVQVLSFLWNHTQNKDPIVANAAYKSLSHFGAGDHTILHLPEEVRPEIQTPDDLDEDEDEEGDEKEVDLSIPGSCYLKLLSLTAPSVLPALEEFFTSLVKQEMVNMPRGVYHSALKGGARLDQGKTVAGIPNFMLKMYETNKQPGLKPGLAGGMLFCYDISMYQSKDGKPLNRLMASRGRSFKQTSLALVHEVHIQPSEWHRAIFLPQAWLAYMTRAYHAILQGRIGELDLQLKHGKEGPEEVQYKKNTAWLWVRDMLTDEITKAAAKDSPVVKGNALLALSSLAVVVSKHEVSLCSDSDRVLEVQPHFLSVKDWVSMIFDTLLVIVDSHYQPRGHFFSSFYHKSYSGENTASAIARSAAATALSLLVPIFIISCKEKVEEILNMLTARLPGKPRADESQAVQIHMGLALGMFLSRLCEEKLSDISSQQMNLLLMKSLDALENCCFDPSLEYNTGCILGVGLVLSLMSHSGQTESRVHVAASLRKLSAYLDDSRSQSRTFQEVLAYTISCVCTSAFSAGIIEAVEAEDIMNKLRLLVDNSQQTSGFALALGNIIHGLSVCGHGKAEDLGNRLLPAWIKTVLTEGAPTMLCLAALHGMVALVGSEGDVMQLKSEAIQSSQSQGRLNEVIRTLTQVISVSGVIGLQSNAIWLLGHLHLSTLSSNQSRTSVPTDYSYLPENSFIRAAIGFFVTGGKKGPESVPPSLLKVVMKPIATVGENHQYPPVNWAALLSPLMRLNFGEEIQQLCLEIMVTQAQSSQNVTTLLGMWVMPPLIHGLSLNIKKYLLLSVPSWIKHVSDEQIVGFVESLMVAVFKAASPLSSPELRPSALQGLSQAMKLPSPSHHLWSLLSEATRKIFDLLPNKIRRNDLELYISVAKCLSEMTDDEADRVAQITESSLEKAAFVRLYLVSQGRFPLMGLTDVLSVAVQHREKDTLAWMTLHSLYQARIVSHANTGVLKRMEWLLELMGYIRNVAYQSTSVQNVALDEALDFLLLIFAAAVVAWADHAAPLLLGLSASWLPWHQENGPAGPASSLLGRSPLHRVTLQEAVTLLPSSMPLLLQKEPWKEQTQKFIDWLFSIMESPKEGLSAKSKDLLKATLLSLRVLPEFKKKAVWTRAYGW", "length": 1805, "header": "tr|A0AAA9TVP1-1|A0AAA9TVP1_BOVIN Isoform 1 of Focadhesin OS=Bos taurus OX=9913 GN=FOCAD PE=4 SV=1 CANONICAL=A0AAA9TVP1-1" }, "locus": { "chromosome": "8", "start_pos": 23699405, "end_pos": 23422763, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000113903.1", "url": "https://www.ensembl.org/id/ENSBTAT00000113903.1" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000100652.1", "url": "https://www.ensembl.org/id/ENSBTAP00000100652.1" } ] } }, { "isoform_ac": "A0ABI0P1X7-1", "url": "https://www.uniprot.org/uniprotkb/A0ABI0P1X7/entry", "sequence": { "sequence": "MLDDIRKRFEFPNSLIQSQELKLFIGPQFCYYLFNKEAVGHLIAAVLKENSFSEKIHQCTNQTPALNLLWEKCCSDNVVVRTACCEGLVALVAQDHAEFSYVLNGILNLIPSTRNTHGLIKALMKLLQMQAVKEGHSGEKNIQDIYNIRNHPQPLITVLEHRPDCWPVILQQLTAFFQQCLERSEVSCIQIMAPFLWYLYCEPPQLQEYAKLRLTLLKVLLKPRVPCDKEQPSILEQQILQLCCDMVPCLQIKDLIQTTEVMLFIEEVYLNLLRYPVFWKIQLTQLTLQLLCVCEVSLNITGECSSLIHLLEHSVELLKEDFPVEPVIIGIALLLLQTPASQQKPILSLALKLLSSAESQKIPKSSLLLVMPLLQILSSTALEDCISVDEEGPSRQQLAVNLLEMVQQERYRDKHRKLSYKLAFPITSMYGSIFTAWRILEVMREESAASDWLASVESLLPITTVIPAHVFLLLAYLLVEDKGRNLHQILKVTTELAQADSSQVPNLIPVLMFKLGRPLAPVLYNDILYTLPTLGVHKVCIGQILRVIQLLGTTPQLKAVTLRLLTSLWEKQDRVYPELQRFMAMSDVPSLSVGKEVQWEKLIAKAASIRDICKQRPYQHGADMLAAISQVLNECTKPDQATPAALVLQGLHALCQAEVVCIRSTWNALSPKLSCDTRPLILKTLSELFSLVPSLTVNTAEYENFKVQVLSFLWNHTQNKDPIVANAAYKSLSHFGAGDHTILHLPEEVRPEIQTPDDLDEDEDEEGDEKEVDLSIPGSCYLKLLSLTAPSVLPALEEFFTSLVKQEMVNMPRGVYHSALKGGARLDQGKTVAGIPNFMLKMYETNKQPGLKPGLAGGMLFCYDISMYQSKDGKPLNRLMASRGRSFKQTSLALVHEVHIQPSEWHRAIFLPQAWLAYMTRAYHAILQGRIGELDLQLKHGKEGPEEVQYKKNTAWLWVRDMLTDEITKAAAKDSPVVKGNALLALSSLAVVVSKHEVSLCSDSDRVLEVQPHFLSVKDWVSMIFDTLLVIVDSHYQPRGHFFSSFYHKSYSGENTASAIARSAAATALSLLVPIFIISCKEKVEEILNMLTARLPGKPRADESQAVQIHMGLALGMFLSRLCEEKLSDISSQQMNLLLMKSLDALENCCFDPSLEYNTGCILGVGLVLSLMSHSGQTESRVHVAASLRKLSAYLDDSRSQSRTFQEVLAYTISCVCTSAFSAGIIEAVEAEDIMNKLRLLVDNSQQTSGFALALGNIIHGLSVCGHGKAEDLGNRLLPAWIKTVLTEGAPTMLCLAALHGMVALVGSEGDVMQLKSEAIQSSQSQGRLNEVIRTLTQVISVSGVIGLQSNAIWLLGHLHLSTLSSNQSRTSVPTDYSYLPENSFIRAAIGFFVTGGKKGPESVPPSLLKVVMKPIATVGENHQYPPVNWAALLSPLMRLNFGEEIQQLCLEIMVTQAQSSQNVTTLLGMWVMPPLIHGLSLNIKKYLLLSVPSWIKHVSDEQIVGFVESLMVAVFKAASPLSSPELRPSALQGLSQAMKLPSPSHHLWSLLSEATRKIFDLLPNKIRRNDLELYISVAKCLSEMTDDEADRVAQITESSLEKAAFVRLYLVSQGRFPLMGLTDVLSVAVQHREKDTLAWMTLHSLYQARIVSHANTGVLKRMEWLLELMGYIRNVAYQSTSVQNVALDEALDFLLLIFAAAVVAWADHAAPLLLGLSASWLPWHQENGPAGPASSLLGRSPLHRVTLQEAVTLLPSSMPLLLQKEPWKEQTQKFIDWLFSIMESPKEGLSAKSKDLLKATLLSLRVLPEFKKKAVWTRAYGW", "length": 1823, "header": "tr|A0ABI0P1X7-1|A0ABI0P1X7_BOVIN Computationally mapped isoform of Focadhesin OS=Bos taurus OX=9913 GN=FOCAD PE=4 SV=1 CANONICAL=A0AAA9TVP1-1" }, "locus": { "chromosome": "8", "start_pos": 23699405, "end_pos": 23422763, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000138734.1", "url": "https://www.ensembl.org/id/ENSBTAT00000138734.1" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000104347.1", "url": "https://www.ensembl.org/id/ENSBTAP00000104347.1" } ] } }, { "isoform_ac": "F1MQ56-1", "url": "https://www.uniprot.org/uniprotkb/F1MQ56/entry", "sequence": { "sequence": "MLDDIRKRFEFPNSLIQSQAVGHLIAAVLKENSFSEKIHQCTNQTPALNLLWEKCCSDNVVVRTACCEGLVALVAQDHAEFSYVLNGILNLIPSTRNTHGLIKALMKLLQMQAVKEGHSGEKNIQDIYNIRSEVSCIQIMAPFLWYLYCEPPQLQEYAKLRLTLLKVLLKPRVPCDKEQPSILEQQILQLCCDMVPCLQIKDLIQTTEVMLFIEEVYLNLLRYPVFWKIQLTQLTLQLLCVCEVSLNITGECSSLIHLLEHSVELLKEDFPVEPVIIGIALLLLQTPASQQKPILSLALKLLSSAESQKIPKSSLLLVMPLLQILSSTALEDCISVDEEGPSRQQLAVNLLEMVQQERYRDKHRKLSYKLAFPITSMYGSIFTAWRILEVMREESAASDWLASVESLLPITTVIPAHVFLLLAYLLVEDKGRNLHQILKVTTELAQADSSQVPNLIPVLMFKLGRPLAPVLYNDILYTLPTLGVHKVCIGQILRVIQLLGTTPQLKAVTLRLLTSLWEKQDRVYPELQRFMAMSDVPSLSVGKEVQWEKLIAKAASIRDICKQRPYQHGADMLAAISQVLNECTKPDQATPAALVLQGLHALCQAEVVCIRSTWNALSPKLSCDTRPLILKTLSELFSLVPSLTVNTAEYENFKVQVLSFLWNHTQNKDPIVANAAYKSLSHFGAGDHTILHLPEEVRPEIQTPDDLDEDEDEEGDEKEVDLSIPGSCYLKLLSLTAPSVLPALEEFFTSLVKQEMVNMPRGVYHSALKGGARLDQGKTVAGIPNFMLKMYETNKQPGLKPGLAGGMLFCYDISMYQSKDGKPLNRLMASRGRSFKQTSLALVHEVHIQPSEWHRAIFLPQAWLAYMTRAYHAILQGRIGELDLQLKHGKEGPEEVQYKKNTAWLWVRDMLTDEITKAAAKDSPVVKGNALLALSSLAVVVSKHEVSLCSDSDRVLEVQPHFLSVKDWVSMIFDTLLVIVDSHYQPRGHFFSSFYHKSYSGENTASAIARSAAATALSLLVPIFIISCKEKVEEILNMLTARLPGKPRADESQAVQIHMGLALGMFLSRLCEEKLSDISSQQMNLLLMKSLDALENCCFDPSLEYNTGCILGVGLVLSLMSHSGQTESRVHVAASLRKLSAYLDDSRSQSRTFQEVLAYTISCVCTSAFSAGIIEAVEAEDIMNKLRLLVDNSQQTSGFALALGNIIHGLSVCGHGKAEDLGNRLLPAWIKTVLTEGAPTMLCLAALHGMVALVGSEGDVMQLKSEAIQSSQSQGRLNEVIRTLTQVISVSGVIGLQSNAIWLLGHLHLSTLSSNQSRTSVPTDYSYLPENSFIRAAIGFFVTGGKKGPESVPPSLLKVVMKPIATVGENHQYPPVNWAALLSPLMRLNFGEEIQQLCLEIMVTQAQSSQNVTTLLGMWVMPPLIHGLSLNIKKYLLLSVPSWIKHVSDEQIVGFVESLMVAVFKAASPLSSPELRPSALQGLSQAMKLPSPSHHLWSLLSEATRKIFDLLPNKIRRNDLELYISVAKCLSEMTDDEADRVAQITESSLEKAAFVRLYLVSQGRFPLMGLTDVLSVAVQHREKDTLAWMTLHSLYQARIVSHANTGVLKRMEWLLELMGYIRNVAYQSTSVQNVALDEALDFLLLIFAAAVVAWADHAAPLLLGLSASWLPWHQENGPAGPASSLLGRSPLHRVTLQEAVTLLPSSMPLLLQKEPWKEQTQKFIDWLFSIMESPKEGLSAKSKDLLKATLLSLRVLPEFKKKAVWTRAYGW", "length": 1771, "header": "tr|F1MQ56-1|A0AAA9TVP1_BOVIN Computationally mapped isoform of Focadhesin OS=Bos taurus OX=9913 GN=FOCAD PE=4 SV=3 CANONICAL=A0AAA9TVP1-1" }, "locus": { "chromosome": "8", "start_pos": 23699405, "end_pos": 23422763, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000061612.4", "url": "https://www.ensembl.org/id/ENSBTAT00000061612.4" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000053542.3", "url": "https://www.ensembl.org/id/ENSBTAP00000053542.3" } ] } } ], "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "other", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 624, "start_aa": "Thr", "end_pos": 624, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr624", "evidence": [ { "id": "", "database": "GlyGen", "url": "https://data.glygen.org/" } ], "filter_code": "000000000000000010000.00000000001000.0.01000" } ], "phosphorylation": [], "glycation": [], "keywords": [ "glycoprotein", "glycoprotein_predicted" ], "publication": [], "pathway": [], "orthologs": [ { "uniprot_canonical_ac": "A0A8V0YGL2-1", "protein_name": "Focadhesin", "gene_name": "FOCAD", "tax_id": 9031, "organism": "Gallus gallus", "sequence": { "sequence": "MSDDIKKRFEFPNTVIQSQAVGHLIAAVLKENASSEKITQTSHQTPALNLLWEKCCSENVALRTACSEGLVALVAENHAELSYVLHGAVNLIPSARNVHGLVKTIWKLLQIQAVQLGRNGDDAVLNLYGIRNNPHPLITVLENRPDCWPVLLQQITVFFHQCPERAQSSCVAIMAPFLRYLYCEPSQIREYAELRMGLLRILLQPRGPKHKEAPCVLEHHILQLLCDFIPHLQVKDLPQVTEALFFLQELFLSLLRFPAFWKVQLSQFCLQLICFCEVCLNVTGECSSLISLIEDNFELLKEVFPVEQCIIGLALLLLQTPESQQKSILSLAYKLFSSPENISATALVLVMPLLQILSSSSVGDCLQEDDSGTTRQQLATDLLEILKEEDVKNKKELMSCKLLFPITSSYCSLYTTWKILELMKEKSAVIDWLSSVRSLLPVTTQVPAHIFLLLAYLLIQEKGDSLRDVLQTTTEVAKADCSQVPSLIPVLVFILGRPLEPALYKDILYTLPSLGVHKVCVAQILRTIHMLGSTPKLRAITLRLMTSLWERQDRIYPELQKFLATSDVPSLVVDKDAQWEKVIAKAACIRDICKQRPYQHGADMLAAISQVLNECTKPDQASPAAIVLQGLQALCEAEVVCINSTWNALSPKLSCDTRPLILKALNELFALVPSLTVNTNEYEKFKAQVLSFLWKNTQNKEAIVAISAYKSLSSFGSDEHTILHLPEQARTEINSLEETDVNEDEEEKEVDLFVPGSSYIKLLSLTPDSVLGAFEEFATSLVKQEMTNMPRGVYHSALRGGATRTDQGKTVAGIPNFLLKMYERNKQPGMTPGLAAGMLLCYDLPVHMGRDGKPINRFLASRGRNFQQILVALIHEVNIQPSEWHRSILLPQSWLGFMSRTYGAVLQGRQAELEMQLKHGKEDPEDVQYKQFTAWLWVRDMLTDVIKGASKESPVVKGNSILALTGLAVAVSKYESNLSSDTEGMPETVPDFLPMQQWIYMVIETLFSIVNSRYRPKGQVFPWFYQKSYSGENTASAIARSCAATALSLLVPVIVVSCKEKVEEVLNMLTARLPGKPNADESQAVQIHMGLALGMFISRLCEEKVSELPGQQMNLVLMKSLDALEDCCFDSSLEYNTGCILGVGLVLSFLSHSSQTESRVHVSASLRKLCAYLDSSEDQSRWVQEVLAYSVACSCVSAFSVGIIEAAEAEEAMNKLRTLVEKNLQTSGFALALGTVVHGLSVCGHGKAEDLSNKLMPSWIKVVIAEGSPTMQRLAAVNGLVALVGSEGGMIQLKSESIQTSQFQSKLNEVIRTLTQIISFSGQIGLQTNAAGLLGHLHMSCLSSTQSRTSVPPDFSYLPESSFIRAAIDFVIESGKKGPESVPAQLVKVALAPIAVVGGSHQYPPVNWASVLSPLIRLNFGDEIKYLCLELAATQAQSSQNAAMLLGMWVAPPLVYSLSTKTQKYLFMSLSLWMKHVAEDKLQAFTEVFLVQQFEVNRIKNPEICQCVLQGLVQAMKIPNPAQYCWGFLCQATEKIFGLLPNKIQRSELEMYVSVAKCISEMADSEIDRIVQISKNNMEKAIFTKVYLISQGRLPLKNLSVVIETSTGYYQKESIVWMFLHSFYHSRIVSHENTGVMKRMDWLLDLMGYIGNLAYTSTPVQNVDLKEVIDFLLWLFAGSVVAWADHSAPLLLGLSAYWSPWKHQTVLPELSDDRVGKHSTDKLAMQETLTLLPSSISLLLAKEPWKEQTQKFIDWLISMLESPKEALSKSSTDLLKVTLLALRSLAEFKKKAVWTKAYGW", "length": 1800 }, "evidence": [ { "id": "A0AAA9TVP1", "url": "https://omabrowser.org/oma/group/A0AAA9TVP1/", "database": "OMA" } ], "glygen_name": "Chicken", "common_name": "Chicken" }, { "uniprot_canonical_ac": "A2AKG8-1", "protein_name": "Focadhesin", "gene_name": "Focad", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MSDDIKKRFDFPNSLIQSQAVGHLIAAVLKEHGVSEKIHQSTNQTAALNLLWEKCCSDHVVVRTACSEGLVALVAQGHAEFSYVLNGILNLTPSARNMSGLIKALMKLLQMQALREGQSGEKDIQDIYSIRNPPQPLITVLEHRPDCWPLLLQQLTAFFQQCPERSEASCVQIMAPFLWYLYCEPSQLEEYAKLRLSLLKVLLQPRGVCEEAQLSVREQSTLQLCCSMLPCLQMKDLMQTTEMMLFVEEVYLSLLRHPGFWKSQLTQLTLQLLCICEVSLKITGECSSLIHLLERSVELLGEDFPVELVIIGIALLLLQMPASQQKPLLNLALKLLSLTEGQKIPKASLLLLVPLLQILSSTALEDCLAMGEEGPSRQQLALSLVEVLQKERHGDDSHTISCRLAFPVSSMYGSIFTAWRILDVIGEESATSDWLATVESLLSATTVIPPHVFLLLAYLLVEDVGQNLQQILRVTTQLAQADSSQVPNLIPVLMFKLGRPLDPVSYNHILYTLPTLGVHKVCVGQILRVIQLLGTTPRLRAVTLRLLTSLWEKQDRVYPELQRFMAVSDAPSLSVGKELQWEKLIAKAASIRDICKQRPYQHGADMLAAISQVLNECTKPDQATPAALVLQGLHALCQAEVVCIRSTWNALSPKLSCDMRPLILKTLSELFSLVPSLTVNTVEYENFKVQVLSFLWTHTQNKNPTVASAAYKSLSHFSAGEHTILHLPEKIRPEMPVPGELDEEESVDLSIPGACFLRLLTITAPSVLPALEEFFTSLVRQEMVNMPRGIYHSALKGGVRSDQGKTVAGIPNFILKTYETNKQPGLKPGLAGGMLFCYDLAMYQSKDGKPLNRLMASRGRSFKQTTLALIHEVHVQLSEWHRAIFLPQAWLAYMTRAYHAILQGRIAELELQLQHGKEGPEEVQYKRSTAWLWVRDMLTDEITKTAAKESPVVKANALLALSSLAVVVSKHEASLCSDSDGVLEIQPNFLPVKEWVSMVLNTLLVIVDSHYHPSGQLFTCFYHKSYSGENTASAIARSAAATALSLLVPVFIISCKEKVEEILNMLTARLPGKPSADESQAVQIHMGLALGMFLSRLCEEKLSDMSGQQMNLLLMKSLDALESCCFDPSLEYNTGCILGVGLALSLMSHSSHTESRVHVAASLRKLSTYLDESGSQSRTFQEVLVYTLSCVCTSAFSAGIIEAAEAEDIMSKLQLLVENNQQTSGFALALGNLVYGLSVCGHGKAEDLGNRLRPSWIKVVLTEGAPTMLCLAALHGLVALVGSDVDVMQLKSEAIQNTHFQARLNEVIRTLTEVISVSGVIGLQSNAIWLLGHLHLSTLSSNQSRTSVPTDYSYLPEGSFIRAAIGFFITGGKKGPEAVPPSLLKVVMKPIATVGESYQYPPANLAALLSPLMRLNFGEEIQQLCLEIAVTQAPSSQSAASLLGLWVMPPLIHGLSLNIKKYLLVSMPLWAKHVSDEQIQGFVENLMVEVFKTASQPCHPEMCLSALQGLSQAMKLPSPSHHLWSLLCDATGRIFDLLPNRIRRNDLELYISIAKCLSEMTDEGVNQVSQITKDNIEKAAFVKLYLVSQGRLPLMSLTDLLTAAMQHPEKETLAWMILHSLYQARIVNHANTGVLKRLEWLLELMGYVRNIAYQSAPIQNVAPEEALDFLMLIFAAAVVAWADHEAPLLLGLSASWLPWHQQNGPGGPAAALLGRSPMHRVTVQEVLTQLPRSMLLLLQKEPWKEQTQKFIDWLLSIMEIPNKAFAAKSKDLLKATLLSLRVLPEFKKKAVWTRAYGW", "length": 1798 }, "evidence": [ { "id": "A0AAA9TVP1", "url": "https://omabrowser.org/oma/group/A0AAA9TVP1/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "E7FGT5-1", "protein_name": "Focadhesin", "gene_name": "focad", "tax_id": 7955, "organism": "Danio rerio", "sequence": { "sequence": "MTETLKARLEFPNSLIQAQAVRTLVAAVLKEKGQNEKICQTSTKGPALESLWEQCSSDSTVVRSACCNALVLLVEQGHADLPYVLNTTLNLLPSARNVQGLIKVVGRLLQIQAGQRENRASFTCPYSIRSFPHPYITVLENRPDCWPALLQEIDDFLQLATDKDEPVFVEMLVPFLRYLYCEPQRLSENALLRQSLLRVLLQPREAPESDRLEEKGASSTRVVRELIRSLFDLLPHMLVDSVTAVVELSSFAESLTAALISHPELWRKELTRLALQLLCACQLTIHLGGELMSLLHTLHHIIPAHAEELPAEQVIMGISLLLLNASVSQQTALLDLAVKIVPPELPPPWGASLLVMPLLHVLSCSSLMEALTDTQTHTKNQKLANSLLQTVQREPARRKEDSMQLDLPLSTWYSELQVAVSVLHRVSTDSTSSSEWLYSLQSSLSVCENVPDTVCLLVSHLIFRSDGDLCRLALETAAAIAEADPAKVPCLLPVLMFKLSRVSDPALSLSVLYTLPKLGTHKLCIPQVLHVLQTVGSSSRLRPVALRLLALLWKKQDRVYPDLQRLMCQLDKSSVVMGKDTQWEQILARAACVRDICRERPYQHGGDMLAAIRDTLLQFSRKDQATPVALALQALQELCRAEVVDICSTWKALSPKLLSDTRPLVLKATAELLALVPDLNVKTEEYEKFGSEAVGVLWGYALSQDSVVASQGFKALSEYPESSHTILHLPEQARPIPKQPEVEDEVKQNEEENEEEEDISVPGASYVKLVSLTSLSVLPALETFLTALVRQEMKQMPRGVYHSALTGGNLRSDQGKTVSGIPSFMLKMYEKNKQPGLKPGLAAGLLLCYDLPVQTDKDGRPIIRFLVSRGRSYQQMLATFIHEVNIQPSEWHRSLLLPQAWRGFMSRAFHALLQGRKAELEMLQKQGKESPEELQYQQHYAWLWVRDRLTDVVKSAAKDSPVVQGNSILALSGLAVVLTRYESNLPAQSESGPEAGPDIFPTVHWLSMVIDTLLSIVSSNSNPKAQVFPWFVHRSYSGENTASVIARSCAALGLALLVPVLVTWRRDSIPSILGTLEAGLPGSATADESQALQFHSGLALGMFLAWLLDERVSDISGQSVAELLMKHLKRLEVCCFDPNLEYNAGCVLGVGLVLSSLSSSSQCERDRVHVSHTLDRLLQSLQDSSNNSRMMQEVVAYSVACVGVSAFSAGIIEASKAEESMNTLRALTEESQQTPGFALALGQTVFGLSSFGHGKAVDIQPRLLAAWTKILLAEGCPTMQRLSALNGLIALVGSETALIQMKSECEETSLQHSRLNEVIRAITQIITFSGTIGLQSNGACLLGHLHLTHASSRHSRTAVPQDFGYLSESSVIRASVDFITEAGRKGPEFTAPQRVKTLLSALAAVGADFQYPPVNWSSVLSPLMRLGFGEEVQHYCLELAASQTQSSQSASLFLGVWLVPPLVHSLSLRTRAHLYESLSCWMKHVAEDKLQVYVDSLAVQQFEPLTRLQRLSLCLSILHGLSRAMTAPNPPQNCWSVLCSTAEKIYNLLPDSIPAAEVALYEAMCSCLSEMSDAEIDRIVKVSEANVEKTAFILSYLVSKGRVPLLGLNDVISTILQVGSKRPISWLLLQGLHQSRFASGPNTGVSKRMEWLLELMGHIRNVAYGSPSVKCVDVLQGTDFLLGVFAAAVVSWADHGGPLLVGIRARWFPWPQSAELCHGLYANPEDTELPVASCLLAIPYSIRKLLDKEPWKSQSQKFIDWLFSITEAPKQAFSETAVLTAKAALMALRSSSEFKKKTVWTRAYGW", "length": 1806 }, "evidence": [ { "id": "A0AAA9TVP1", "url": "https://omabrowser.org/oma/group/A0AAA9TVP1/", "database": "OMA" } ], "glygen_name": "Zebrafish", "common_name": "Zebrafish" }, { "uniprot_canonical_ac": "F1LU27-1", "protein_name": "Focadhesin", "gene_name": "Focad", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MSDDIKKRFDFPNSLIQSQAVGHLIAAVLKEHGASEKIHQSTNQTAALNLLWEKSCSDNVVVRTACSEGLVALVAQGHAEFSYVLNGILNLIPSARNMSGLIKALMKLLQMQASREGQGGAKDLQDLYSIRNPPQPLITVLEHRPDCWPLLLQQLTAFFQQCPERSEASCVQIMAPFLWYLYCEPSQLQEYAKLRLSLLKVLLQPRGVCEEAQPSVLEQQILQLCCNMVPCLQMKDLMQTTEMTLFVEEVYLSLLRHPAFWKRQLTQLTVQLLCICEVSLKTTGECSSLIQLLERSVELLGEDFPVKLVIIGIALILLQTPASQQKPVLNLTLKLLSLTEGQRIPKASLLLLVPLLQILSSTALEDCLATGEEGPSRQQLALSLLEVLQRECHGDDRHTISCRLAFPVSSMYGSVFTACRILEVMGEASAASDWLAAVESLLPATTVIPPHVFLLLAHLLVEDGGQNLQQILKVTTQLAQADSSQVPHLIPVLMFKLGRPLDPVSYNHILYTLPTLGVHKVCVGQILRVIQLLGTTPRLRAVTLRLLTSLWEKQDRVYPELQRFMAMSDAPSLSVGKELQWEKLIAKAASIRDICKQRPYQHGADMLAAISQVLNECTKPDQASPAALVLQGLHALCQAEVVCIRSTWNALSPKLSCDMRPLILKTLSELFSLVPSLTVNTVEYENFKVQVLTFLWTHTQNKDPIVASAAYKSLSHFSAGEHTILHLPEKIRPEMPVPDELDEEESVDLSIPGSCYLRLLTITAPSILPALEEFFTSLVRQEMVNMPRGIYHSALKGGVCSDQGKTVAGIPNFILKTYETNKQPGLKPGLAGGMLFCYDVAMYQSKDGKPLNRLMASRGRTFKQTTLALVHEVHVQLSEWHRAIFLPQAWLAYMTRAYHAILQGRIAELELQLQHGKEGPEEVQYKRSTAWLWVRDMLTDEITKTAAKESPVVKGNALLALSSLAVVVSKHEASLSSESDGVLEVQPNFLPVKEWVSMVLNTVLVIVDSHYHPRGQLFTCFYHKSYSGENTASAIARSAAATALSLLVPVFIISCKEKVEEILNMLTARLPGKPSADESQAVQIHMGLALGMFLSRLCEEKLSDMSGQQMSLLLMKSLDALESCCFDPSLEHNTGCILGVGLALSLMSHSSHTESRVHVAASLRKLSAYLDESGSQSRTFQEVLAYTLSCVCTSAFSAGIIEAVEAEETMTKLQLLVENNQQTSGFALALGNLVYGLSVCGHGKAEDLGNRLRPSWIKIVLSEGAPTMLCLAALHGLVALVGSDVDVMQFQSEAIHNSQFQARLNEVIRTLTEVISVSGVIGLQSNAIWLLGHLHLSTLSSNQSRTSVPTDYSYLPEGSFIRAAIGFFITGGKKGPEAVPPSLLKVVMKPIATVGENYQYPPANLAALLSPLMRLNFGEEIQQLCLEIAVSQAPSSQSAAALLGLWVMPPLVHGLSLNIKKYLLVSMPLWAKHVSDEQIQGFVENLMVAVFKPASQPCHPEMCPSALQGLSQAMKLPSPSHHLWSLLCDATGRIFDLLPNRIRRNDLELYISIAKCLSEMTDEGANQVSQITKENIEKAAFVKLYLISQGRLPLMSLTDLLTAAMQHPSKETLAWMILHSLYQARIVNHTNTGVLKRLEWLLELMGYMRNIAYQSASAQNVPPAEALDFLMLIFAAAVVAWADHEAPLLLGLSASWLPWHQENGPGGPAAALLGRSPMHRVTVQEVLTLLPTSMLLLLQKEPWKEQTQKFIDWLFSIMEIPNEAFAATSKDLLKATLLSLRVLPEFKKKAVWTRAYGW", "length": 1798 }, "evidence": [ { "id": "A0AAA9TVP1", "url": "https://omabrowser.org/oma/group/A0AAA9TVP1/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "Q5VW36-1", "protein_name": "Focadhesin", "gene_name": "FOCAD", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MSDDIRKRFEFPNSLIQSQAVGHLIAAVLKENGFSEKIHQSTNQTPALNLLWEKCCSDNVVVRTACCEGLVALVAQDHAEFSYVLNGILNLIPSTRNTHGLIKAIMHLLQMQALKEGQGGEKNIQSIYTIRNHPHPLITVLEHRPDCWPVFLQQLTAFFQQCPERLEVSCIQIMAPFLWYLYCEPSQLQEYAKLRLALLKVLLQPQVLCDKDQPSILEQQILQLCCDIVPCLQVKDLIQTTEAMMFIEEVCLSLLRHPVFWKIQLTQMSLQLLCVSEVSLKITGECSSSIHLLEHSVELLKEDFPVELVIIGIALLLLQTPASQQKPILNLALKLLSVTEDQKIPKSSLLLVMPILQILSSTALEDCISVDEEGPSRQQLALNLLEMIQQECYRDDHQKLSYKLVCPVTSMYGTIFTAWRILEVMTDSSAASDWLASVESLLPITAVIPAPAFLLLAHLLVEDKGQNLHQILKVTTELAQADSSQVPNLIPVLMFKLGRPLEPILYNDILYTLPKLGVHKVCIGQILRIIQLLGTTPRLRAVTLRLLTSLWEKQDRVYPELQRFMAVSDVPSLSVGKEVQWEKLIAKAASIRDICKQRPYQHGADMLAAISQVLNECTKPDQATPAALVLQGLHALCQAEVVCIRSTWNALSPKLSCDTRPLILKTLSELFSLVPSLTVNTTEYENFKVQVLSFLWTHTQNKDPIVANAAYRSLANFSAGEHTILHLPEKIRPEIPIPEELDDDEDVEDVDLSVPGSCYLKLLSLTPPLVLPALEEFFTSLVKQEMVNMPRGIYHSALKGGARSDQGKTVAGIPNFILKMYETNKQPGLKPGLAGGMLFCYDVSMYQSKDGKPLNRLMASRGRSFKQTSLALVHEVHIQLSEWHRAIFLPQAWLAYMNRAYHAILQGRLGELELQLKHGKEEPEEVQYKKSTAWLWVRDMLTDEITKAAAKESPVVKGNALLALSSLAVVVSRHEASLSSDSDGLLEVQPNFLSMKEWVSMVLDTLLVIVDSHYQPRGQLLSWFYYKSYSGENTASAIARSAAATALSLLVPVFIISCKEKVEEILNMLTARLPGKPSADESQAVQIHMGLALGMFLSRLCEEKLSDISGQEMNLLLMKSLDALENCCFDTSLEYNTGCILGVGLVLSLMSHSSQMQSRVHVAALLRKLSAHVDDSGSQSRTFQEVLAYTLSCVCTSAFSAGIIEATEAEDVMNKLRLLVENSQQTSGFALALGNIVHGLSVCGHGKAEDLGSKLLPAWIRIVLTEGTPTMLCLAALHGMVALVGSEGDVMQLKSEAIQTSHFQGRLNEVIRTLTQVISVSGVIGLQSNAVWLLGHLHLSTLSSSQSRASVPTDYSYLPESSFIGAAIGFFITGGKKGPESVPPSLLKVVMKPIATVGESYQYPPVNWAALLSPLMRLNFGEEIQQLCLEIMVTQAQSSQNAAALLGLWVTPPLIHSLSLNTKRYLLISAPLWIKHISDEQILGFVENLMVAVFKAASPLGSPELCPSALHGLSQAMKLPSPAHHLWSLLSEATGKIFDLLPNKIRRKDLELYISIAKCLLEMTDDDANRIAQVTKSNIEKAAFVKLYLVSQGRFPLVNLTDMLSVAVQHREKEVLAWMILHSLYQARIVSHANTGVLKRMEWLLELMGYIRNVAYQSTSFHNTALDKALDFFLLIFATAVVAWADHTAPLLLGLSASWLPWHQENGPAGPVPSFLGRSPMHRVTLQEVLTLLPNSMALLLQKEPWKEQTQKFIDWLFSIMESPKEALSAQSRDLLKATLLSLRVLPEFKKKAVWTRAYGW", "length": 1801 }, "evidence": [ { "id": "A0AAA9TVP1", "url": "https://omabrowser.org/oma/group/A0AAA9TVP1/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" } ], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 2, "go_terms": [ { "name": "cytosol", "id": "GO:0005829", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005829", "evidence": [ { "database": "UniProtKB", "id": "A0AAA9TVP1", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TVP1" } ], "pmid": "" }, { "name": "focal adhesion", "id": "GO:0005925", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005925", "evidence": [ { "database": "UniProtKB", "id": "A0AAA9TVP1", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TVP1" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 1, "go_terms": [ { "name": "regulation of post-transcriptional gene silencing", "id": "GO:0060147", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0060147", "evidence": [ { "database": "UniProtKB", "id": "A0AAA9TVP1", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TVP1" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 1349, "end_pos": 1351, "annotation": "n_glycosylation_sequon" }, { "start_pos": 1445, "end_pos": 1447, "annotation": "n_glycosylation_sequon" }, { "start_pos": 281, "end_pos": 283, "annotation": "n_glycosylation_sequon" }, { "start_pos": 43, "end_pos": 45, "annotation": "n_glycosylation_sequon" }, { "start_pos": 697, "end_pos": 699, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A0AAA9TVP1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TVP1" }, { "id": "PF12530", "database": "Pfam", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF12530" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "DUF3730", "eco_id": "ECO_0000259", "start_pos": 490, "end_pos": 714, "start_aa": "Ile", "end_aa": "Leu", "glycosite_overlap": [] }, { "evidence": [ { "id": "A0AAA9TVP1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TVP1" }, { "id": "PF11229", "database": "Pfam", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF11229" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "Focadhesin C-terminal", "eco_id": "ECO_0000259", "start_pos": 1217, "end_pos": 1805, "start_aa": "Met", "end_aa": "Trp", "glycosite_overlap": [] } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" }, { "name": "homologset.oma", "label": "OMA Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [ 624 ], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 1349, "end_pos": 1351 }, { "start_pos": 1445, "end_pos": 1447 }, { "start_pos": 281, "end_pos": 283 }, { "start_pos": 43, "end_pos": 45 }, { "start_pos": 697, "end_pos": 699 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 1 }, { "field": "total_sites", "count": 1 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 1 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "exact_sites", "count": 1 }, { "field": "exact_o_linked_sites", "count": 1 }, { "field": "fuzzy_sites", "count": 0 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_pos", "start_aa", "end_pos", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 1 }, { "field": "total_sites", "count": 1 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 1 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "exact_sites", "count": 1 }, { "field": "exact_o_linked_sites", "count": 1 }, { "field": "fuzzy_sites", "count": 0 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_pos", "start_aa", "end_pos", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ], "tool_support": { "graph_view": "yes" } }, { "uniprot_canonical_ac": "A0AAA9TVB5-1", "uniprot_ac": "A0AAA9TVB5", "uniprot_id": "A0AAA9TVB5_BOVIN", "mass": { "chemical_mass": 35526.0, "monoisotopic_mass": 35526.0 }, "refseq": {}, "gene_names": [ { "name": "CIB2", "type": "recommended", "evidence": [ { "id": "A0AAA9TVB5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TVB5" } ] } ], "protein_names": [ { "name": "Calcium and integrin-binding family member 2", "type": "recommended", "evidence": [ { "id": "A0AAA9TVB5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TVB5/entry#names_and_taxonomy" } ] }, { "name": "Calcium and integrin-binding protein 1", "type": "synonym", "evidence": [ { "id": "A0AAA9TVB5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TVB5/entry#names_and_taxonomy" } ] }, { "name": "Calmyrin", "type": "synonym", "evidence": [ { "id": "A0AAA9TVB5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TVB5/entry#names_and_taxonomy" } ] } ], "function": [], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Bos taurus", "taxid": 9913, "evidence": [ { "database": "UniProtKB", "id": "A0AAA9TVB5", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TVB5" } ], "common_name": "Bovine", "glygen_name": "Bovine", "reference_species": "Bos taurus [9913]" } ], "gene": [ { "name": "CIB2", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TVB5", "locus": { "chromosome": "21", "start_pos": 30485335, "end_pos": 30508968, "strand": "+", "evidence": [ { "database": "Ensembl Gene", "id": "ENSBTAG00000010981", "url": "https://www.ensembl.org/id/ENSBTAG00000010981" } ] } } ], "crossref": [ { "id": "A0AAA9TVB5", "url": "https://alphafold.ebi.ac.uk/entry/A0AAA9TVB5", "database": "AlphaFoldDB", "categories": [] }, { "id": "ENSBTAG00000010981", "url": "https://bgee.org/?page=gene&gene_id=ENSBTAG00000010981", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "cd00051", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd00051", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "100337259", "url": "https://www.ncbi.nlm.nih.gov/gene/100337259", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR002048", "url": "https://www.ebi.ac.uk/interpro/entry/IPR002048", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR011992", "url": "https://www.ebi.ac.uk/interpro/entry/IPR011992", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR018247", "url": "https://www.ebi.ac.uk/interpro/entry/IPR018247", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR051433", "url": "https://www.ebi.ac.uk/interpro/entry/IPR051433", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "A0A3Q1MPI3", "url": "https://www.orthodb.org/?gene=A0A3Q1MPI3", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "F1N1B4", "url": "https://www.orthodb.org/?gene=F1N1B4", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR45791", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR45791", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR45791:SF5", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR45791:SF5", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF13499", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF13499", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "A0A3Q1MPI3", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1MPI3", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A3Q1MPI3-1", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1MPI3-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0AAA9RSB5", "url": "https://www.uniprot.org/uniprotkb/A0AAA9RSB5", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0AAA9RSB5-1", "url": "https://www.uniprot.org/uniprotkb/A0AAA9RSB5-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0AAA9SJY0", "url": "https://www.uniprot.org/uniprotkb/A0AAA9SJY0", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0AAA9SJY0-1", "url": "https://www.uniprot.org/uniprotkb/A0AAA9SJY0-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0AAA9TVB5", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TVB5", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0AAA9TVB5-1", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TVB5-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0ABI0P171", "url": "https://www.uniprot.org/uniprotkb/A0ABI0P171", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0ABI0P171-1", "url": "https://www.uniprot.org/uniprotkb/A0ABI0P171-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0ABI0P238", "url": "https://www.uniprot.org/uniprotkb/A0ABI0P238", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0ABI0P238-1", "url": "https://www.uniprot.org/uniprotkb/A0ABI0P238-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "F1N1B4", "url": "https://www.uniprot.org/uniprotkb/F1N1B4", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "F1N1B4-1", "url": "https://www.uniprot.org/uniprotkb/F1N1B4-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MDRSGPATLSPASPGLSAAGSSRVRPADAGAGARRAGQRLPRPGRPLAGPGRAAAGSRAPALSRPRGGVAALRVRFPASQAPAPPPPVGCGARRGAARRGGRGPVAVESCPPRGWRGPRARGSGGRGWEAAPGRASDAAAATMGNKQTIFTEEQLDNYQDCTFFNKKDILKLHARFYELAPNLVPMDYRKSPIVHVPMSLIIQMPELRENPFKERIVEAFSEDGEGNLTFNDFVDMFSVLCESAPRELKASYAFKIYDFNTDNFICKEDLQLTLARLTKSELDEDEVVLVCDKVIEEADLDGDGKLGFADFEDMIAKAPDFLSTFHIRI", "length": 329, "header": "tr|A0AAA9TVB5-1|A0AAA9TVB5_BOVIN Isoform 1 of Calcium and integrin-binding family member 2 OS=Bos taurus OX=9913 GN=CIB2 PE=4 SV=1 CANONICAL=A0AAA9TVB5-1" }, "isoforms": [ { "isoform_ac": "A0A3Q1MPI3-1", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1MPI3/entry", "sequence": { "sequence": "MGNKQTIFTEEQLDNYQENPFKERIVEAFSEDGEGNLTFNDFVDMFSVLCESAPRELKASYAFKIYDFNTDNFICKEDLQLTLARLTKSELDEDEVVLVCDKVIEEADLDGDGKLGFADFEDMIAKAPDFLSTFHIRI", "length": 138, "header": "tr|A0A3Q1MPI3-1|A0AAA9TVB5_BOVIN Computationally mapped isoform of Calcium and integrin-binding family member 2 OS=Bos taurus OX=9913 GN=CIB2 PE=4 SV=2 CANONICAL=A0AAA9TVB5-1" }, "locus": { "chromosome": "21", "start_pos": 30508343, "end_pos": 30486339, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000085676.2", "url": "https://www.ensembl.org/id/ENSBTAT00000085676.2" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000073829.2", "url": "https://www.ensembl.org/id/ENSBTAP00000073829.2" } ] } }, { "isoform_ac": "A0AAA9RSB5-1", "url": "https://www.uniprot.org/uniprotkb/A0AAA9RSB5/entry", "sequence": { "sequence": "MSCLPGDCTFFNKKDILKLHARFYELAPNLVPMDYRKSPIVHVPMSLIIQMPELRENPFKERIVEAFSEDGEGNLTFNDFVDMFSVLCESAPRELKASYAFKIYDFNTDNFICKEDLQLTLARLTKSELDEDEVVLVCDKVIEEADLDGDGKLGFADFEDMIAKAPDFLSTFHIRI", "length": 176, "header": "tr|A0AAA9RSB5-1|A0AAA9TVB5_BOVIN Computationally mapped isoform of Calcium and integrin-binding family member 2 OS=Bos taurus OX=9913 GN=CIB2 PE=4 SV=1 CANONICAL=A0AAA9TVB5-1" }, "locus": { "chromosome": "21", "start_pos": 30504296, "end_pos": 30486339, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000097774.1", "url": "https://www.ensembl.org/id/ENSBTAT00000097774.1" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000075407.1", "url": "https://www.ensembl.org/id/ENSBTAP00000075407.1" } ] } }, { "isoform_ac": "A0AAA9SJY0-1", "url": "https://www.uniprot.org/uniprotkb/A0AAA9SJY0/entry", "sequence": { "sequence": "MGNKQTIFTEEQLDNYQDCTFFNKKDILNHRRIKAVTCLAHRLLRESKEGKIRLHARFYELAPNLVPMDYRKSPIVHVPMSLIIQMPELRENPFKERIVEAFSEDGEGNLTFNDFVDMFSVLCESAPRELKASYAFKIYDFNTDNFICKEDLQLTLARLTKSELDEDEVVLVCDKVIEEADLDGDGKLGFADFEDMIAKAPDFLSTFHIRI", "length": 211, "header": "tr|A0AAA9SJY0-1|A0AAA9TVB5_BOVIN Computationally mapped isoform of Calcium and integrin-binding family member 2 OS=Bos taurus OX=9913 GN=CIB2 PE=4 SV=1 CANONICAL=A0AAA9TVB5-1" }, "locus": { "chromosome": "21", "start_pos": 30508343, "end_pos": 30486339, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000096006.1", "url": "https://www.ensembl.org/id/ENSBTAT00000096006.1" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000086613.1", "url": "https://www.ensembl.org/id/ENSBTAP00000086613.1" } ] } }, { "isoform_ac": "A0AAA9TVB5-1", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TVB5/entry", "sequence": { "sequence": "MDRSGPATLSPASPGLSAAGSSRVRPADAGAGARRAGQRLPRPGRPLAGPGRAAAGSRAPALSRPRGGVAALRVRFPASQAPAPPPPVGCGARRGAARRGGRGPVAVESCPPRGWRGPRARGSGGRGWEAAPGRASDAAAATMGNKQTIFTEEQLDNYQDCTFFNKKDILKLHARFYELAPNLVPMDYRKSPIVHVPMSLIIQMPELRENPFKERIVEAFSEDGEGNLTFNDFVDMFSVLCESAPRELKASYAFKIYDFNTDNFICKEDLQLTLARLTKSELDEDEVVLVCDKVIEEADLDGDGKLGFADFEDMIAKAPDFLSTFHIRI", "length": 329, "header": "tr|A0AAA9TVB5-1|A0AAA9TVB5_BOVIN Isoform 1 of Calcium and integrin-binding family member 2 OS=Bos taurus OX=9913 GN=CIB2 PE=4 SV=1 CANONICAL=A0AAA9TVB5-1" }, "locus": { "chromosome": "21", "start_pos": 30508769, "end_pos": 30486339, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000117076.1", "url": "https://www.ensembl.org/id/ENSBTAT00000117076.1" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000100515.1", "url": "https://www.ensembl.org/id/ENSBTAP00000100515.1" } ] } }, { "isoform_ac": "A0ABI0P171-1", "url": "https://www.uniprot.org/uniprotkb/A0ABI0P171/entry", "sequence": { "sequence": "MATHSSTLAWKIPWTEEPGDFQESSPAPQFKGINSLAFCLHYGPALTTENPFKERIVEAFSEDGEGNLTFNDFVDMFSVLCESAPRELKASYAFKIYDFNTDNFICKEDLQLTLARLTKSELDEDEVVLVCDKVIEEADLDGDGKLGFADFEDMIAKAPDFLSTFHIRI", "length": 169, "header": "tr|A0ABI0P171-1|A0ABI0P171_BOVIN Computationally mapped isoform of Calcium and integrin-binding family member 2 OS=Bos taurus OX=9913 GN=CIB2 PE=4 SV=1 CANONICAL=A0AAA9TVB5-1" }, "locus": { "chromosome": "21", "start_pos": 30491183, "end_pos": 30486339, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000136624.1", "url": "https://www.ensembl.org/id/ENSBTAT00000136624.1" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000104709.1", "url": "https://www.ensembl.org/id/ENSBTAP00000104709.1" } ] } }, { "isoform_ac": "A0ABI0P238-1", "url": "https://www.uniprot.org/uniprotkb/A0ABI0P238/entry", "sequence": { "sequence": "MWSIIAMTILPSVPCPFLCPGCFSSMYPGLHARFYELAPNLVPMDYRKSPIVHVPMSLIIQMPELRENPFKERIVEAFSEDGEGNLTFNDFVDMFSVLCESAPRELKASYAFKIYDFNTDNFICKEDLQLTLARLTKSELDEDEVVLVCDKVIEEADLDGDGKLGFADFEDMIAKAPDFLSTFHIRI", "length": 187, "header": "tr|A0ABI0P238-1|A0ABI0P238_BOVIN Computationally mapped isoform of Calcium and integrin-binding family member 2 OS=Bos taurus OX=9913 GN=CIB2 PE=4 SV=1 CANONICAL=A0AAA9TVB5-1" }, "locus": { "chromosome": "21", "start_pos": 30500682, "end_pos": 30486339, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000141853.1", "url": "https://www.ensembl.org/id/ENSBTAT00000141853.1" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000107213.1", "url": "https://www.ensembl.org/id/ENSBTAP00000107213.1" } ] } }, { "isoform_ac": "F1N1B4-1", "url": "https://www.uniprot.org/uniprotkb/F1N1B4/entry", "sequence": { "sequence": "MLHARFYELAPNLVPMDYRKSPIVHVPMSLIIQMPELRENPFKERIVEAFSEDGEGNLTFNDFVDMFSVLCESAPRELKASYAFKIYDFNTDNFICKEDLQLTLARLTKSELDEDEVVLVCDKVIEEADLDGDGKLGFADFEDMIAKAPDFLSTFHIRI", "length": 159, "header": "tr|F1N1B4-1|A0AAA9TVB5_BOVIN Computationally mapped isoform of Calcium and integrin-binding family member 2 OS=Bos taurus OX=9913 GN=CIB2 PE=4 SV=4 CANONICAL=A0AAA9TVB5-1" }, "locus": { "chromosome": "21", "start_pos": 30497464, "end_pos": 30486339, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000014575.7", "url": "https://www.ensembl.org/id/ENSBTAT00000014575.7" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000014575.7", "url": "https://www.ensembl.org/id/ENSBTAP00000014575.7" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [], "orthologs": [], "go_annotation": { "categories": [ { "name": "Molecular Function", "total": 2, "go_terms": [ { "name": "magnesium ion binding", "id": "GO:0000287", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000287", "evidence": [ { "database": "UniProtKB", "id": "A0AAA9TVB5", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TVB5" } ], "pmid": "" }, { "name": "calcium ion binding", "id": "GO:0005509", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005509", "evidence": [ { "database": "UniProtKB", "id": "A0AAA9TVB5", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TVB5" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 14, "go_terms": [ { "name": "cytoplasm", "id": "GO:0005737", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005737", "evidence": [ { "database": "UniProtKB", "id": "A0AAA9TVB5", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TVB5" } ], "pmid": "" }, { "name": "photoreceptor inner segment", "id": "GO:0001917", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0001917", "evidence": [ { "database": "UniProtKB", "id": "A0AAA9TVB5", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TVB5" } ], "pmid": "" }, { "name": "cell periphery", "id": "GO:0071944", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0071944", "evidence": [ { "database": "UniProtKB", "id": "A0AAA9TVB5", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TVB5" } ], "pmid": "" }, { "name": "sarcolemma", "id": "GO:0042383", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0042383", "evidence": [ { "database": "UniProtKB", "id": "A0AAA9TVB5", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TVB5" } ], "pmid": "" }, { "name": "photoreceptor outer segment", "id": "GO:0001750", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0001750", "evidence": [ { "database": "UniProtKB", "id": "A0AAA9TVB5", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TVB5" } ], "pmid": "" }, { "name": "stereocilium", "id": "GO:0032420", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0032420", "evidence": [ { "database": "UniProtKB", "id": "A0AAA9TVB5", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TVB5" } ], "pmid": "" }, { "name": "centrosome", "id": "GO:0005813", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005813", "evidence": [ { "database": "UniProtKB", "id": "A0AAA9TVB5", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TVB5" } ], "pmid": "" }, { "name": "lamellipodium", "id": "GO:0030027", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030027", "evidence": [ { "database": "UniProtKB", "id": "A0AAA9TVB5", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TVB5" } ], "pmid": "" }, { "name": "growth cone", "id": "GO:0030426", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030426", "evidence": [ { "database": "UniProtKB", "id": "A0AAA9TVB5", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TVB5" } ], "pmid": "" }, { "name": "perikaryon", "id": "GO:0043204", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0043204", "evidence": [ { "database": "UniProtKB", "id": "A0AAA9TVB5", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TVB5" } ], "pmid": "" }, { "name": "perinuclear region of cytoplasm", "id": "GO:0048471", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0048471", "evidence": [ { "database": "UniProtKB", "id": "A0AAA9TVB5", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TVB5" } ], "pmid": "" }, { "name": "apical plasma membrane", "id": "GO:0016324", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016324", "evidence": [ { "database": "UniProtKB", "id": "A0AAA9TVB5", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TVB5" } ], "pmid": "" }, { "name": "ruffle membrane", "id": "GO:0032587", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0032587", "evidence": [ { "database": "UniProtKB", "id": "A0AAA9TVB5", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TVB5" } ], "pmid": "" }, { "name": "filopodium tip", "id": "GO:0032433", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0032433", "evidence": [ { "database": "UniProtKB", "id": "A0AAA9TVB5", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TVB5" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 7, "go_terms": [ { "name": "calcium ion homeostasis", "id": "GO:0055074", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0055074", "evidence": [ { "database": "UniProtKB", "id": "A0AAA9TVB5", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TVB5" } ], "pmid": "" }, { "name": "angiogenesis", "id": "GO:0001525", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0001525", "evidence": [ { "database": "UniProtKB", "id": "A0AAA9TVB5", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TVB5" } ], "pmid": "" }, { "name": "cell adhesion", "id": "GO:0007155", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007155", "evidence": [ { "database": "UniProtKB", "id": "A0AAA9TVB5", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TVB5" } ], "pmid": "" }, { "name": "spermatogenesis", "id": "GO:0007283", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007283", "evidence": [ { "database": "UniProtKB", "id": "A0AAA9TVB5", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TVB5" } ], "pmid": "" }, { "name": "cell differentiation", "id": "GO:0030154", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030154", "evidence": [ { "database": "UniProtKB", "id": "A0AAA9TVB5", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TVB5" } ], "pmid": "" }, { "name": "cell division", "id": "GO:0051301", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0051301", "evidence": [ { "database": "UniProtKB", "id": "A0AAA9TVB5", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TVB5" } ], "pmid": "" }, { "name": "apoptotic process", "id": "GO:0006915", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006915", "evidence": [ { "database": "UniProtKB", "id": "A0AAA9TVB5", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TVB5" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 227, "end_pos": 229, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A0AAA9TVB5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TVB5" }, { "id": "PS50222", "database": "PROSITE", "url": "https://prosite.expasy.org/PS50222" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "EF-hand", "eco_id": "ECO_0000259", "start_pos": 208, "end_pos": 243, "start_aa": "Arg", "end_aa": "Ser", "glycosite_overlap": [] } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 227, "end_pos": 229 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ], "tool_support": { "graph_view": "yes" } }, { "uniprot_canonical_ac": "A0AAA9TWE6-1", "uniprot_ac": "A0AAA9TWE6", "uniprot_id": "A0AAA9TWE6_BOVIN", "mass": { "chemical_mass": 44920.0, "monoisotopic_mass": 44920.0 }, "refseq": {}, "gene_names": [ { "name": "RAB35", "type": "recommended", "evidence": [ { "id": "A0AAA9TWE6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TWE6" } ] } ], "protein_names": [ { "name": "Ras-related protein Rab-35", "type": "recommended", "evidence": [ { "id": "A0AAA9TWE6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TWE6/entry#names_and_taxonomy" } ] }, { "name": "3.6.5.2", "type": "synonym", "evidence": [ { "id": "A0AAA9TWE6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TWE6/entry#names_and_taxonomy" } ] } ], "function": [], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Bos taurus", "taxid": 9913, "evidence": [ { "database": "UniProtKB", "id": "A0AAA9TWE6", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TWE6" } ], "common_name": "Bovine", "glygen_name": "Bovine", "reference_species": "Bos taurus [9913]" } ], "gene": [ { "name": "RAB35", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TWE6", "locus": { "chromosome": "17", "start_pos": 62472792, "end_pos": 62494330, "strand": "+", "evidence": [ { "database": "Ensembl Gene", "id": "ENSBTAG00000022044", "url": "https://www.ensembl.org/id/ENSBTAG00000022044" } ] } } ], "crossref": [ { "id": "A0AAA9TWE6", "url": "https://alphafold.ebi.ac.uk/entry/A0AAA9TWE6", "database": "AlphaFoldDB", "categories": [] }, { "id": "ENSBTAG00000022044", "url": "https://bgee.org/?page=gene&gene_id=ENSBTAG00000022044", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "IPR001806", "url": "https://www.ebi.ac.uk/interpro/entry/IPR001806", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR005225", "url": "https://www.ebi.ac.uk/interpro/entry/IPR005225", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR027417", "url": "https://www.ebi.ac.uk/interpro/entry/IPR027417", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR050227", "url": "https://www.ebi.ac.uk/interpro/entry/IPR050227", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "A0A3Q1MQN4", "url": "https://www.orthodb.org/?gene=A0A3Q1MQN4", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR47977", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR47977", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00071", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00071", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "19669", "url": "https://www.rhea-db.org/rhea/19669", "database": "Rhea", "categories": [ "Enzyme and Pathway" ] }, { "id": "A0A3Q1MQN4", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1MQN4", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A3Q1MQN4-1", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1MQN4-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0AAA9RYK5", "url": "https://www.uniprot.org/uniprotkb/A0AAA9RYK5", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0AAA9RYK5-1", "url": "https://www.uniprot.org/uniprotkb/A0AAA9RYK5-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0AAA9S351", "url": "https://www.uniprot.org/uniprotkb/A0AAA9S351", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0AAA9S351-1", "url": "https://www.uniprot.org/uniprotkb/A0AAA9S351-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0AAA9S917", "url": "https://www.uniprot.org/uniprotkb/A0AAA9S917", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0AAA9S917-1", "url": "https://www.uniprot.org/uniprotkb/A0AAA9S917-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0AAA9SLI4", "url": "https://www.uniprot.org/uniprotkb/A0AAA9SLI4", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0AAA9SLI4-1", "url": "https://www.uniprot.org/uniprotkb/A0AAA9SLI4-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0AAA9SXY4", "url": "https://www.uniprot.org/uniprotkb/A0AAA9SXY4", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0AAA9SXY4-1", "url": "https://www.uniprot.org/uniprotkb/A0AAA9SXY4-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0AAA9SYH3", "url": "https://www.uniprot.org/uniprotkb/A0AAA9SYH3", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0AAA9SYH3-1", "url": "https://www.uniprot.org/uniprotkb/A0AAA9SYH3-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0AAA9TL43", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TL43", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0AAA9TL43-1", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TL43-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0AAA9TWE6", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TWE6", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0AAA9TWE6-1", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TWE6-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0AAF6DLS8", "url": "https://www.uniprot.org/uniprotkb/A0AAF6DLS8", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0AAF6DLS8-1", "url": "https://www.uniprot.org/uniprotkb/A0AAF6DLS8-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "VHSPEKLGARRKPRPARSLRASRSLSAALAGLKDEATAASPPRATVGLARHSGILAAKAWLQLRSRSSQHSRPRTAGGRRWWRRRSLKSHGQDKPAPPGPRQGAGAVRERGEGVAGRHCGCAEAGPGAAPAQWRGGAGRSEAAAAAAAAEEEEEEEGERREVFLSVPAVCSGSGSAAAGAARREPRIPRPAPTPPARPRARARASPARHGPGLRPPLQAAHHRRQRCRQEQLTVTFCRQHFLSYITTIGVDFKIRTVEINGEKVKLQIWDTAGQERFRTITSTYYRGTHGVIVVYDVTSAESFVNVKRWLHEINQNCDDVCRILVGNKNDDPERKVVETEDAYKFAGQMGIQLFETSAKENVNVEEMFNCITELVLRAKKDNLAKQQQQQQNDVVKLTKNSKRKKRCC", "length": 408, "header": "tr|A0AAA9TWE6-1|A0AAA9TWE6_BOVIN Isoform 1 of Ras-related protein Rab-35 OS=Bos taurus OX=9913 GN=RAB35 PE=3 SV=1 CANONICAL=A0AAA9TWE6-1" }, "isoforms": [ { "isoform_ac": "A0A3Q1MQN4-1", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1MQN4/entry", "sequence": { "sequence": "VSEPRVPPLKRCSWACGHVRAGFLLCLADPAGLGGGTGGHRTGVGKSSLLLRFADNTFSGSYITTIGVDFKIRTVEINGEKVKLQIWDTAGQERFRTITSTYYRGTHGVIVVYDVTSAESFVNVKRWLHEINQNCDDVCRILVGNKNDDPERKVVETEDAYKFAGQMGIQLFETSAKENVNVEEMFNCITELVLRAKKDNLAKQQQQQQNDVVKLTKNSKRKKRCC", "length": 226, "header": "tr|A0A3Q1MQN4-1|A0AAA9TWE6_BOVIN Computationally mapped isoform of Ras-related protein Rab-35 OS=Bos taurus OX=9913 GN=RAB35 PE=3 SV=2 CANONICAL=A0AAA9TWE6-1" }, "locus": { "chromosome": "17", "start_pos": 62486792, "end_pos": 62474854, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000082458.2", "url": "https://www.ensembl.org/id/ENSBTAT00000082458.2" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000073926.2", "url": "https://www.ensembl.org/id/ENSBTAP00000073926.2" } ] } }, { "isoform_ac": "A0AAA9RYK5-1", "url": "https://www.uniprot.org/uniprotkb/A0AAA9RYK5/entry", "sequence": { "sequence": "PWSSLAILWSWREPGSSLGTTSFLTLTLGELFRLSEPRFSHLRGVGKSSLLLRFADNTFSGSYITTIGVDFKIRTVEINGEKVKLQIWDTAGQERFRTITSTYYRGTHGVIVVYDVTSAESFVNVKRWLHEINQNCDDVCRILVGNKNDDPERKVVETEDAYKFAGQMGIQLFETSAKENVNVEEMFNCITELVLRAKKDNLAKQQQQQQNDVVKLTKNSKRKKRCC", "length": 227, "header": "tr|A0AAA9RYK5-1|A0AAA9TWE6_BOVIN Computationally mapped isoform of Ras-related protein Rab-35 OS=Bos taurus OX=9913 GN=RAB35 PE=3 SV=1 CANONICAL=A0AAA9TWE6-1" }, "locus": { "chromosome": "17", "start_pos": 62491038, "end_pos": 62474854, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000128352.1", "url": "https://www.ensembl.org/id/ENSBTAT00000128352.1" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000076355.1", "url": "https://www.ensembl.org/id/ENSBTAP00000076355.1" } ] } }, { "isoform_ac": "A0AAA9S351-1", "url": "https://www.uniprot.org/uniprotkb/A0AAA9S351/entry", "sequence": { "sequence": "ARTVAKDCGCFISFNPDSRHLWLSSTKEAGQHSALFSCPLLAGDSCLPPLPVSWLALLHLLRYYRGTHGVIVVYDVTSAESFVNVKRWLHEINQNCDDVCRILVGNKNDDPERKVVETEDAYKFAGQMGIQLFETSAKENVNVEEMFNCITELVLRAKKDNLAKQQQQQQNDVVKLTKNSKRKKRCC", "length": 187, "header": "tr|A0AAA9S351-1|A0AAA9TWE6_BOVIN Computationally mapped isoform of Ras-related protein Rab-35 OS=Bos taurus OX=9913 GN=RAB35 PE=3 SV=1 CANONICAL=A0AAA9TWE6-1" }, "locus": { "chromosome": "17", "start_pos": 62479693, "end_pos": 62474854, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000105364.1", "url": "https://www.ensembl.org/id/ENSBTAT00000105364.1" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000080348.1", "url": "https://www.ensembl.org/id/ENSBTAP00000080348.1" } ] } }, { "isoform_ac": "A0AAA9S917-1", "url": "https://www.uniprot.org/uniprotkb/A0AAA9S917/entry", "sequence": { "sequence": "GVGKSSLLLRFADNTFSGSYITTIGVDFKIRTVEINGEKVKLQIWDTAGQERFRTITSTYYRGTHGVIVVYDVTSAESFVNVKRWLHEINQNCDDVCRILVGNKNDDPERKVVETEDAYKFAGQMGIQLFETSAKENVNVEEMFNCITELVLRAKKDNLAKQQQQQQNDVVKLTKNSKRKKRCC", "length": 184, "header": "tr|A0AAA9S917-1|A0AAA9TWE6_BOVIN Computationally mapped isoform of Ras-related protein Rab-35 OS=Bos taurus OX=9913 GN=RAB35 PE=3 SV=1 CANONICAL=A0AAA9TWE6-1" }, "locus": { "chromosome": "17", "start_pos": 62487664, "end_pos": 62474854, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000135510.1", "url": "https://www.ensembl.org/id/ENSBTAT00000135510.1" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000080415.1", "url": "https://www.ensembl.org/id/ENSBTAP00000080415.1" } ] } }, { "isoform_ac": "A0AAA9SLI4-1", "url": "https://www.uniprot.org/uniprotkb/A0AAA9SLI4/entry", "sequence": { "sequence": "GRGAEPRSGGAGARGSGPGSRSARRADPSAPRVTLVQSRDPLELEGAGFESRDYQLPHPDLGRVVSPFRTSVLSFERRGRGVGKSSLLLRFADNTFSGSYITTIGVDFKIRTVEINGEKVKLQIWDTAGQERFRTITSTYYRGTHGVIVVYDVTSAESFVNVKRWLHEINQNCDDVCRILVGNKNDDPERKVVETEDAYKFAGQMGIQLFETSAKENVNVEEMFNCITELVLRAKKDNLAKQQQQQQNDVVKLTKNSKRKKRCC", "length": 264, "header": "tr|A0AAA9SLI4-1|A0AAA9TWE6_BOVIN Computationally mapped isoform of Ras-related protein Rab-35 OS=Bos taurus OX=9913 GN=RAB35 PE=3 SV=1 CANONICAL=A0AAA9TWE6-1" }, "locus": { "chromosome": "17", "start_pos": 62491138, "end_pos": 62474854, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000107502.1", "url": "https://www.ensembl.org/id/ENSBTAT00000107502.1" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000086106.1", "url": "https://www.ensembl.org/id/ENSBTAP00000086106.1" } ] } }, { "isoform_ac": "A0AAA9SXY4-1", "url": "https://www.uniprot.org/uniprotkb/A0AAA9SXY4/entry", "sequence": { "sequence": "AGRHCGCAEAGPGAAPAQWRGGAGRSEAAAAAAAAEEEEEEEGERREVFLSVPAVCSGSGSAAAGAARREPRIPRPAPTPPARPRARARASPARHGPGLRPPLQAAHHRRQRCRQEQLTVTFCRQHFLRYYRGTHGVIVVYDVTSAESFVNVKRWLHEINQNCDDVCRILVGNKNDDPERKVVETEDAYKFAGQMGIQLFETSAKENVNVEEMFNCITELVLRAKKDNLAKQQQQQQNDVVKLTKNSKRKKRCC", "length": 254, "header": "tr|A0AAA9SXY4-1|A0AAA9TWE6_BOVIN Computationally mapped isoform of Ras-related protein Rab-35 OS=Bos taurus OX=9913 GN=RAB35 PE=3 SV=1 CANONICAL=A0AAA9TWE6-1" }, "locus": { "chromosome": "17", "start_pos": 62491649, "end_pos": 62474854, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000109459.1", "url": "https://www.ensembl.org/id/ENSBTAT00000109459.1" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000088174.1", "url": "https://www.ensembl.org/id/ENSBTAP00000088174.1" } ] } }, { "isoform_ac": "A0AAA9SYH3-1", "url": "https://www.uniprot.org/uniprotkb/A0AAA9SYH3/entry", "sequence": { "sequence": "QAQRPSSTPQAGPPSADSRHLWLSSTKEAGQHSALFSCPLLAGDSCLPPLPVSWLALLHLLRYYRGTHGVIVVYDVTSAESFVNVKRWLHEINQNCDDVCRILVGNKNDDPERKVVETEDAYKFAGQMGIQLFETSAKENVNVEEMFNCITELVLRAKKDNLAKQQQQQQNDVVKLTKNSKRKKRCC", "length": 187, "header": "tr|A0AAA9SYH3-1|A0AAA9TWE6_BOVIN Computationally mapped isoform of Ras-related protein Rab-35 OS=Bos taurus OX=9913 GN=RAB35 PE=3 SV=1 CANONICAL=A0AAA9TWE6-1" }, "locus": { "chromosome": "17", "start_pos": 62478436, "end_pos": 62474854, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000133508.1", "url": "https://www.ensembl.org/id/ENSBTAT00000133508.1" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000089302.1", "url": "https://www.ensembl.org/id/ENSBTAP00000089302.1" } ] } }, { "isoform_ac": "A0AAA9TL43-1", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TL43/entry", "sequence": { "sequence": "HPLPPRRHSEVSQRSLGFLTAGSAPLLQSILQLCSQEASLGVGKSSLLLRFADNTFSGSYITTIGVDFKIRTVEINGEKVKLQIWDTAGQERFRTITSTYYRGTHGVIVVYDVTSAESFVNVKRWLHEINQNCDDVCRILVGNKNDDPERKVVETEDAYKFAGQMGIQLFETSAKENVNVEEMFNCITELVLRAKKDNLAKQQQQQQNDVVKLTKNSKRKKRCC", "length": 224, "header": "tr|A0AAA9TL43-1|A0AAA9TWE6_BOVIN Computationally mapped isoform of Ras-related protein Rab-35 OS=Bos taurus OX=9913 GN=RAB35 PE=3 SV=1 CANONICAL=A0AAA9TWE6-1" }, "locus": { "chromosome": "17", "start_pos": 62493715, "end_pos": 62474854, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000116449.1", "url": "https://www.ensembl.org/id/ENSBTAT00000116449.1" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000097669.1", "url": "https://www.ensembl.org/id/ENSBTAP00000097669.1" } ] } }, { "isoform_ac": "A0AAA9TWE6-1", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TWE6/entry", "sequence": { "sequence": "VHSPEKLGARRKPRPARSLRASRSLSAALAGLKDEATAASPPRATVGLARHSGILAAKAWLQLRSRSSQHSRPRTAGGRRWWRRRSLKSHGQDKPAPPGPRQGAGAVRERGEGVAGRHCGCAEAGPGAAPAQWRGGAGRSEAAAAAAAAEEEEEEEGERREVFLSVPAVCSGSGSAAAGAARREPRIPRPAPTPPARPRARARASPARHGPGLRPPLQAAHHRRQRCRQEQLTVTFCRQHFLSYITTIGVDFKIRTVEINGEKVKLQIWDTAGQERFRTITSTYYRGTHGVIVVYDVTSAESFVNVKRWLHEINQNCDDVCRILVGNKNDDPERKVVETEDAYKFAGQMGIQLFETSAKENVNVEEMFNCITELVLRAKKDNLAKQQQQQQNDVVKLTKNSKRKKRCC", "length": 408, "header": "tr|A0AAA9TWE6-1|A0AAA9TWE6_BOVIN Isoform 1 of Ras-related protein Rab-35 OS=Bos taurus OX=9913 GN=RAB35 PE=3 SV=1 CANONICAL=A0AAA9TWE6-1" }, "locus": { "chromosome": "17", "start_pos": 62491991, "end_pos": 62474854, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000096693.1", "url": "https://www.ensembl.org/id/ENSBTAT00000096693.1" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000101501.1", "url": "https://www.ensembl.org/id/ENSBTAP00000101501.1" } ] } }, { "isoform_ac": "A0AAF6DLS8-1", "url": "https://www.uniprot.org/uniprotkb/A0AAF6DLS8/entry", "sequence": { "sequence": "SAARDVFSGRCSGHALGTGAQGVGKSSLLLRFADNTFSGSYITTIGVDFKIRTVEINGEKVKLQIWDTAGQERFRTITSTYYRGTHGVIVVYDVTSAESFVNVKRWLHEINQNCDDVCRILVGNKNDDPERKVVETEDAYKFAGQMGIQLFETSAKENVNVEEMFNCITELVLRAKKDNLAKQQQQQQNDVVKLTKNSKRKKRCC", "length": 205, "header": "tr|A0AAF6DLS8-1|A0AAF6DLS8_BOVIN Computationally mapped isoform of Ras-related protein Rab-35 OS=Bos taurus OX=9913 GN=RAB35 PE=3 SV=1 CANONICAL=A0AAA9TWE6-1" }, "locus": { "chromosome": "17", "start_pos": 62486366, "end_pos": 62474854, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000029514.6", "url": "https://www.ensembl.org/id/ENSBTAT00000029514.6" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000029514.6", "url": "https://www.ensembl.org/id/ENSBTAP00000029514.6" } ] } } ], "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "other", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 193, "start_aa": "Thr", "end_pos": 193, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr193", "evidence": [ { "id": "", "database": "GlyGen", "url": "https://data.glygen.org/" } ], "filter_code": "000000000000000010000.00000000001000.0.01000" } ], "phosphorylation": [], "glycation": [], "keywords": [ "enzyme", "glycoprotein", "glycoprotein_predicted" ], "publication": [], "pathway": [], "orthologs": [], "go_annotation": { "categories": [ { "name": "Molecular Function", "total": 4, "go_terms": [ { "name": "GTP binding", "id": "GO:0005525", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005525", "evidence": [ { "database": "UniProtKB", "id": "A0AAA9TWE6", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TWE6" } ], "pmid": "" }, { "name": "metal ion binding", "id": "GO:0046872", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0046872", "evidence": [ { "database": "UniProtKB", "id": "A0AAA9TWE6", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TWE6" } ], "pmid": "" }, { "name": "G protein activity", "id": "GO:0003925", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003925", "evidence": [ { "database": "UniProtKB", "id": "A0AAA9TWE6", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TWE6" } ], "pmid": "" }, { "name": "GTPase activity", "id": "GO:0003924", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003924", "evidence": [ { "database": "UniProtKB", "id": "A0AAA9TWE6", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TWE6" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 5, "go_terms": [ { "name": "endosome", "id": "GO:0005768", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005768", "evidence": [ { "database": "UniProtKB", "id": "A0AAA9TWE6", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TWE6" } ], "pmid": "" }, { "name": "plasma membrane", "id": "GO:0005886", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005886", "evidence": [ { "database": "UniProtKB", "id": "A0AAA9TWE6", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TWE6" } ], "pmid": "" }, { "name": "clathrin-coated pit", "id": "GO:0005905", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005905", "evidence": [ { "database": "UniProtKB", "id": "A0AAA9TWE6", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TWE6" } ], "pmid": "" }, { "name": "melanosome", "id": "GO:0042470", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0042470", "evidence": [ { "database": "UniProtKB", "id": "A0AAA9TWE6", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TWE6" } ], "pmid": "" }, { "name": "clathrin-coated vesicle", "id": "GO:0030136", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030136", "evidence": [ { "database": "UniProtKB", "id": "A0AAA9TWE6", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TWE6" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 1, "go_terms": [ { "name": "protein transport", "id": "GO:0015031", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0015031", "evidence": [ { "database": "UniProtKB", "id": "A0AAA9TWE6", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TWE6" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [], "ptm_annotation": [], "interactions": [], "reactions": [ { "id": "19669", "name": "", "equation": "GTP + H2O = GDP + phosphate + H(+)", "summary": "", "cellular_location": "", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [ "Q08E00-1", "Q5E9J3-1", "A6QP66-1", "Q2KHU8-1", "Q2KIA5-1", "F1MM29-1", "P08239-1", "P04896-1", "P63097-1", "Q7YS69-1", "Q0VCJ7-1", "A0AAA9SVR8-1", "P81948-1", "Q2KJ93-1", "A0AAA9TES1-1", "P61223-1", "Q2HJB8-1", "Q0IIG7-1", "Q3ZCJ7-1", "Q27957-1", "Q2HJ86-1", "A0A3Q1LMP2-1", "F1MB25-1", "Q58DS9-1", "A0AAA9S306-1", "A0A3Q1NEF8-1", "A4FV54-1", "A6H7I5-1", "F2Z4D5-1", "G3N1U2-1", "O18956-1", "P62998-1", "Q32KN8-1", "Q3MHP2-1", "Q3T054-1", "Q3T0F5-1", "Q3T0T7-1", "Q56JV3-1", "F1MNI4-1", "Q8HZJ5-1", "P61585-1", "P62833-1", "P68103-1", "Q08DI5-1", "Q2HJH2-1", "Q2T9U1-1", "Q2TBH7-1", "Q3MHP5-1", "Q3SX43-1", "Q3SYU2-1", "P81947-1", "P84080-1", "Q08DF4-1", "Q2KI07-1", "Q2TA29-1", "Q3T0D7-1", "A6QLJ3-1", "A6QNM2-1", "A6QR46-1", "Q1LZ78-1", "Q2KHZ2-1", "G3MYK6-1", "Q58D56-1", "Q32KW9-1", "P11023-1", "Q58DW6-1", "Q9TU25-1", "P10948-1", "Q2HJI8-1", "P10949-1", "Q0IIG8-1", "Q29RR0-1", "Q32PH8-1", "Q58DS5-1", "Q1RMR4-1", "Q3ZC27-1", "P49410-1", "A0A140T898-1", "E1BPU0-1", "A0AAA9S5W8-1", "A0AAA9SLN0-1", "A0AAF6Z672-1", "Q17R06-1", "Q58D72-1", "P82922-1", "Q2HJF8-1", "Q17QU4-1", "Q2YDM7-1", "A0AAA9T9T1-1", "A0A3Q1MDX0-1", "F1N2J9-1", "Q17QB7-1", "Q3SWY9-1", "Q5E9M9-1", "A0A3S5ZPA2-1", "A0AAA9SV95-1", "A0AAA9TWE6-1", "F1N6Y7-1", "F1N7V2-1", "A0AAA9SGM6-1", "A0AAA9TNQ2-1", "A0AAA9TS74-1", "F6Q1G9-1", "A0AAF6YXF5-1", "A5D7J5-1", "P04695-1", "Q3ZBW5-1", "A4FUD1-1", "A0A3Q1M0B9-1", "A6H7F2-1", "F1MHP4-1", "A0A3Q1MGR4-1", "A0A3Q1NCE9-1", "Q0P5E2-1", 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"database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1MDX0" } ] } ] }, { "uniprot_ac": "A0A3Q1MGR4", "gene_name": "RAB37", "activity": [ { "ec_number": "3.6.5.2", "activity": "GTP + H2O = GDP + phosphate + H(+).", "evidence": [ { "id": "A0A3Q1MGR4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1MGR4" } ] }, { "ec_number": "3.6.5.2", "activity": "", "evidence": [ { "id": "A0A3Q1MGR4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1MGR4" } ] } ] }, { "uniprot_ac": "A0A3Q1N147", "gene_name": "RAB1A", "activity": [ { "ec_number": "3.6.5.2", "activity": "GTP + H2O = GDP + phosphate + H(+).", "evidence": [ { "id": "A0A3Q1N147", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1N147" } ] }, { "ec_number": "3.6.5.2", "activity": "", "evidence": [ { "id": "A0A3Q1N147", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1N147" } ] } ] }, { "uniprot_ac": "A0A3Q1NCE9", "gene_name": 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"database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3S5ZPA2" } ] }, { "ec_number": "3.6.5.2", "activity": "", "evidence": [ { "id": "A0A3S5ZPA2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3S5ZPA2" } ] } ] }, { "uniprot_ac": "A0AAA9S306", "gene_name": "OPA1", "activity": [ { "ec_number": "3.6.5.5", "activity": "GTP + H2O = GDP + phosphate + H(+).", "evidence": [ { "id": "A0AAA9S306", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9S306" } ] }, { "ec_number": "3.6.5.5", "activity": "", "evidence": [ { "id": "A0AAA9S306", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9S306" } ] } ] }, { "uniprot_ac": "A0AAA9S5W8", "gene_name": "RAB12", "activity": [ { "ec_number": "3.6.5.2", "activity": "GTP + H2O = GDP + phosphate + H(+).", "evidence": [ { "id": "A0AAA9S5W8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9S5W8" } ] }, { "ec_number": "3.6.5.2", "activity": "", 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"Protein Classification", "Other" ] }, { "id": "PF10366", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF10366", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF10367", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF10367", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "A0A3Q1MTV0", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1MTV0", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A3Q1MTV0-1", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1MTV0-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0AAA9TU88", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TU88", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0AAA9TU88-1", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TU88-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "F1MWF9", "url": "https://www.uniprot.org/uniprotkb/F1MWF9", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "F1MWF9-1", "url": "https://www.uniprot.org/uniprotkb/F1MWF9-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MDCTPPGSSVHGISQGRILERVAISSSRGSSQPRDPTRISCIGRAAANMMSTKAFTLVPAIEREQLLSDRDRGLLECVECCGRNLYVGTSDCFVYHFLLEEKTLPGGSATFTATRQLHRHLGFKKAVSELRAASALSRLLVLCDGCISLVHMLSLEPVPSGARIKGATAFALNENPVSGDPFCVEVCIISVKRRTIQVFLVYEDRVQIVREVSTPEQPLAVAVDGHFLCLALTTQYIILNYSTGAAQDLFPFCSEERRPIVKRIGRQEFLLAGPGGLGMFATVAGISQRAPVRWSENVIGAAVCFPYVVALDDEFITVHSMLDQQQKQTLPFKEGHILQDFEGRVIVATSKGVYILVPLPLEKQIQDLLASHRVEEALVLAKGARRNIPKEKFQVMYRRILLQAGFIQFAQLQFLEAKELFRSGQLDVRELISLYPLLLPTSSSFTRSHPPLHEFADLNQLTQGDQDKVAKCKRFLMSYLNEVRSTEVANGYKEDIDTALLKLYAEADHDSLLDLLVTENFCLLPDSAAWLEKHKKYFALGLLYHYNHQDAAAVQLWVSIVNGDIQDSTRSDLYEYIVDFLTYSTDPDLVWRHADWVLQRSQEVGVQVFTKRPLDEQQSGFNPDDIISCLKKYPQALVKYLEHLVTERRLQKEEYHTHLAVLYLDEVLQQRPCTPDKDAEVTETQAKLRRLLQESDLYRVHFLMDRTRGAGLPLESAILHGKLEQHEEALHILVHELADFPAAEDYCLWRSEGRDPPYRQRLFHLLLAVYLGPGPAAPARTVAAVDLLNRHAVEFDAAQVLQLLPGTWSVQLLRPFLMGAMRDSIHARRTTQVAVGLARSENLIYKYDKMKLKGSSVRLSDKKLCQMCQNPFLEPVFVRYPNGGLVHTHCAASRHTEPSSPSAGART", "length": 907, "header": "tr|A0AAA9TU88-1|A0AAA9TU88_BOVIN Isoform 1 of Transforming growth factor beta receptor associated protein 1 OS=Bos taurus OX=9913 GN=TGFBRAP1 PE=4 SV=1 CANONICAL=A0AAA9TU88-1" }, "isoforms": [ { "isoform_ac": "A0A3Q1MTV0-1", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1MTV0/entry", "sequence": { "sequence": "MMSTKAFTLVPAIEREQLLSDRDRGLLECVECCGRNLYVGTSDCFVYHFLLEEKTLPGGSATFTATRQLHRHLGFKKAVSELRAASALSRLLVLCDGCISLVHMLSLEPVPSGARIKGATAFALNENPVSGDPFCVEVCIISVKRRTIQVFLVYEDRVQIVREVSTPEQPLAVAVDGHFLCLALTTQYIILNYSTGAAQDLFPFCSEERRPIVKRIGRQEFLLAGPGGLGMFATVAGISQRAPVRWSENVIGAAVCFPYVVALDDEFITVHSMLDQQQKQTLPFKEGHILQDFEGRVIVATSKGVYILVPLPLEKQIQDLLASHRVEEALVLAKGARRNIPKEKFQVMYRRILLQAGFIQFAQLQFLEAKELFRSGQLDVRELISLYPLLLPTSSSFTRSHPPLHEFADLNQLTQGDQDKVAKCKRFLMSYLNEVRSTEVANGYKEDIDTALLKLYAEADHDSLLDLLVTENFCLLPDSAAWLEKHKKYFALGLLYHYNHQDAAAVQLWVSIVNGDIQDSTRSDLYEYIVDFLTYSTDPDLVWRHADWVLQRSQEVGVQVFTKRPLDEQQSGFNPDDIISCLKKYPQALVKYLEHLVTERRLQKEEYHTHLAVLYLDEVLQQRPCTPDKDAEVTETQAKLRRLLQESDLYRVHFLMDRTRGAGLPLESAILHGKLEQHEEALHILVHELADFPAAEDYCLWRSEGRDPPYRQRLFHLLLAVYLGPGPAAPARTVAAVDLLNRHAVEFDAAQVLQLLPGTWSVQLLRPFLMGAMRDSIHARRTTQVAVGLARSENLIYKYDKDTWKEQWACRSIQTALMSTGSSACVPSLPFVPDEAERKLRSTLRQKALPDVPKPLPRACVR", "length": 862, "header": "tr|A0A3Q1MTV0-1|A0AAA9TU88_BOVIN Computationally mapped isoform of Transforming growth factor beta receptor associated protein 1 OS=Bos taurus OX=9913 GN=TGFBRAP1 PE=4 SV=2 CANONICAL=A0AAA9TU88-1" }, "locus": { "chromosome": "11", "start_pos": 9242990, "end_pos": 9218294, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000074055.2", "url": "https://www.ensembl.org/id/ENSBTAT00000074055.2" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000058166.2", "url": "https://www.ensembl.org/id/ENSBTAP00000058166.2" } ] } }, { "isoform_ac": "A0AAA9TU88-1", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TU88/entry", "sequence": { "sequence": "MDCTPPGSSVHGISQGRILERVAISSSRGSSQPRDPTRISCIGRAAANMMSTKAFTLVPAIEREQLLSDRDRGLLECVECCGRNLYVGTSDCFVYHFLLEEKTLPGGSATFTATRQLHRHLGFKKAVSELRAASALSRLLVLCDGCISLVHMLSLEPVPSGARIKGATAFALNENPVSGDPFCVEVCIISVKRRTIQVFLVYEDRVQIVREVSTPEQPLAVAVDGHFLCLALTTQYIILNYSTGAAQDLFPFCSEERRPIVKRIGRQEFLLAGPGGLGMFATVAGISQRAPVRWSENVIGAAVCFPYVVALDDEFITVHSMLDQQQKQTLPFKEGHILQDFEGRVIVATSKGVYILVPLPLEKQIQDLLASHRVEEALVLAKGARRNIPKEKFQVMYRRILLQAGFIQFAQLQFLEAKELFRSGQLDVRELISLYPLLLPTSSSFTRSHPPLHEFADLNQLTQGDQDKVAKCKRFLMSYLNEVRSTEVANGYKEDIDTALLKLYAEADHDSLLDLLVTENFCLLPDSAAWLEKHKKYFALGLLYHYNHQDAAAVQLWVSIVNGDIQDSTRSDLYEYIVDFLTYSTDPDLVWRHADWVLQRSQEVGVQVFTKRPLDEQQSGFNPDDIISCLKKYPQALVKYLEHLVTERRLQKEEYHTHLAVLYLDEVLQQRPCTPDKDAEVTETQAKLRRLLQESDLYRVHFLMDRTRGAGLPLESAILHGKLEQHEEALHILVHELADFPAAEDYCLWRSEGRDPPYRQRLFHLLLAVYLGPGPAAPARTVAAVDLLNRHAVEFDAAQVLQLLPGTWSVQLLRPFLMGAMRDSIHARRTTQVAVGLARSENLIYKYDKMKLKGSSVRLSDKKLCQMCQNPFLEPVFVRYPNGGLVHTHCAASRHTEPSSPSAGART", "length": 907, "header": "tr|A0AAA9TU88-1|A0AAA9TU88_BOVIN Isoform 1 of Transforming growth factor beta receptor associated protein 1 OS=Bos taurus OX=9913 GN=TGFBRAP1 PE=4 SV=1 CANONICAL=A0AAA9TU88-1" }, "locus": { "chromosome": "11", "start_pos": 9247099, "end_pos": 9218206, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000096888.1", "url": "https://www.ensembl.org/id/ENSBTAT00000096888.1" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000100120.1", "url": "https://www.ensembl.org/id/ENSBTAP00000100120.1" } ] } }, { "isoform_ac": "F1MWF9-1", "url": "https://www.uniprot.org/uniprotkb/F1MWF9/entry", "sequence": { "sequence": "MMSTKAFTLVPAIEREQLLSDRDRGLLECVECCGRNLYVGTSDCFVYHFLLEEKTLPGGSATFTATRQLHRHLGFKKAVSELRAASALSRLLVLCDGCISLVHMLSLEPVPSGARIKGATAFALNENPVSGDPFCVEVCIISVKRRTIQVFLVYEDRVQIVREVSTPEQPLAVAVDGHFLCLALTTQYIILNYSTGAAQDLFPFCSEERRPIVKRIGRQEFLLAGPGGLGMFATVAGISQRAPVRWSENVIGAAVCFPYVVALDDEFITVHSMLDQQQKQTLPFKEGHILQDFEGRVIVATSKGVYILVPLPLEKQIQDLLASHRVEEALVLAKGARRNIPKEKFQDFDCSSQVALMVMYRRILLQAGFIQFAQLQFLEAKELFRSGQLDVRELISLYPLLLPTSSSFTRSHPPLHEFADLNQLTQGDQDKVAKCKRFLMSYLNEVRSTEVANGYKEDIDTALLKLYAEADHDSLLDLLVTENFCLLPDSAAWLEKHKKYFALGLLYHYNHQDAAAVQLWVSIVNGDIQDSTRSDLYEYIVDFLTYSTDPDLVWRHADWVLQRSQEVGVQVFTKRPLDEQQSGFNPDDIISCLKKYPQALVKYLEHLVTERRLQKEEYHTHLAVLYLDEVLQQRPCTPDKDAEVTETQAKLRRLLQESDLYRVHFLMDRTRGAGLPLESAILHGKLEQHEEALHILVHELADFPAAEDYCLWRSEGRDPPYRQRLFHLLLAVYLGPGPAAPARTVAAVDLLNRHAVEFDAAQVLQLLPGTWSVQLLRPFLMGAMRDSIHARRTTQVAVGLARSENLIYKYDKMKLKGSSVRLSDKKLCQMCQNPFLEPVFVRYPNGGLVHTHCAASRHTEPSSPSAGART", "length": 870, "header": "tr|F1MWF9-1|A0AAA9TU88_BOVIN Computationally mapped isoform of Transforming growth factor beta receptor associated protein 1 OS=Bos taurus OX=9913 GN=TGFBRAP1 PE=4 SV=2 CANONICAL=A0AAA9TU88-1" }, "locus": { "chromosome": "11", "start_pos": 9242990, "end_pos": 9218206, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000028967.7", "url": "https://www.ensembl.org/id/ENSBTAT00000028967.7" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000028967.6", "url": "https://www.ensembl.org/id/ENSBTAP00000028967.6" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [], "orthologs": [], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 4, "go_terms": [ { "name": "cytoplasm", "id": "GO:0005737", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005737", "evidence": [ { "database": "UniProtKB", "id": "A0AAA9TU88", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TU88" } ], "pmid": "" }, { "name": "early endosome", "id": "GO:0005769", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005769", "evidence": [ { "database": "UniProtKB", "id": "A0AAA9TU88", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TU88" } ], "pmid": "" }, { "name": "membrane", "id": "GO:0016020", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016020", "evidence": [ { "database": "UniProtKB", "id": "A0AAA9TU88", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TU88" } ], "pmid": "" }, { "name": "CORVET complex", "id": "GO:0033263", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0033263", "evidence": [ { "database": "UniProtKB", "id": "A0AAA9TU88", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TU88" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 6, "go_terms": [ { "name": "intracellular protein transport", "id": "GO:0006886", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006886", "evidence": [ { "database": "UniProtKB", "id": "A0AAA9TU88", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TU88" } ], "pmid": "" }, { "name": "vesicle-mediated transport", "id": "GO:0016192", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016192", "evidence": [ { "database": "UniProtKB", "id": "A0AAA9TU88", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TU88" } ], "pmid": "" }, { "name": "signal transduction", "id": "GO:0007165", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007165", "evidence": [ { "database": "UniProtKB", "id": "A0AAA9TU88", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TU88" } ], "pmid": "" }, { "name": "regulation of DNA-templated transcription", "id": "GO:0006355", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006355", "evidence": [ { "database": "UniProtKB", "id": "A0AAA9TU88", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TU88" } ], "pmid": "" }, { "name": "endosome to lysosome transport", "id": "GO:0008333", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008333", "evidence": [ { "database": "UniProtKB", "id": "A0AAA9TU88", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TU88" } ], "pmid": "" }, { "name": "endosomal vesicle fusion", "id": "GO:0034058", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0034058", "evidence": [ { "database": "UniProtKB", "id": "A0AAA9TU88", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TU88" } ], "pmid": "" } ] }, { "name": "Molecular Function", "total": 2, "go_terms": [ { "name": "transforming growth factor beta receptor binding", "id": "GO:0005160", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005160", "evidence": [ { "database": "UniProtKB", "id": "A0AAA9TU88", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TU88" } ], "pmid": "" }, { "name": "SMAD binding", "id": "GO:0046332", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0046332", "evidence": [ { "database": "UniProtKB", "id": "A0AAA9TU88", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TU88" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 240, "end_pos": 242, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A0AAA9TU88", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TU88" }, { "id": "PS50219", "database": "PROSITE", "url": "https://prosite.expasy.org/PS50219" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "CNH", "eco_id": "ECO_0000259", "start_pos": 72, "end_pos": 345, "start_aa": "Arg", "end_aa": "Val", "glycosite_overlap": [] } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 240, "end_pos": 242 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", 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"uniprot_canonical_ac": "A0AAA9TVB0-1", "uniprot_ac": "A0AAA9TVB0", "uniprot_id": "A0AAA9TVB0_BOVIN", "mass": { "chemical_mass": 48898.0, "monoisotopic_mass": 48898.0 }, "refseq": {}, "gene_names": [ { "name": "PRR5L", "type": "recommended", "evidence": [ { "id": "A0AAA9TVB0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TVB0" } ] } ], "protein_names": [ { "name": "Proline rich 5 like", "type": "synonym", "evidence": [ { "id": "A0AAA9TVB0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TVB0/entry#names_and_taxonomy" } ] } ], "function": [], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Bos taurus", "taxid": 9913, "evidence": [ { "database": "UniProtKB", "id": "A0AAA9TVB0", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TVB0" } ], "common_name": "Bovine", "glygen_name": "Bovine", "reference_species": "Bos taurus [9913]" } ], "gene": [ { "name": "PRR5L", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TVB0", "locus": { "chromosome": "15", "start_pos": 66918824, "end_pos": 66840069, "strand": "-", "evidence": [ { "database": "Ensembl Gene", "id": "ENSBTAG00000021029", "url": "https://www.ensembl.org/id/ENSBTAG00000021029" } ] } } ], "crossref": [ { "id": "A0AAA9TVB0", "url": "https://alphafold.ebi.ac.uk/entry/A0AAA9TVB0", "database": "AlphaFoldDB", "categories": [] }, { "id": "ENSBTAG00000021029", "url": "https://bgee.org/?page=gene&gene_id=ENSBTAG00000021029", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "505048", "url": "https://www.ncbi.nlm.nih.gov/gene/505048", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR013745", "url": "https://www.ebi.ac.uk/interpro/entry/IPR013745", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "F1MZG7", "url": "https://www.orthodb.org/?gene=F1MZG7", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR32428", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR32428", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR32428:SF3", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR32428:SF3", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF08539", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF08539", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "A0A3Q1MWD9", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1MWD9", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A3Q1MWD9-1", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1MWD9-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0AAA9RXW1", "url": "https://www.uniprot.org/uniprotkb/A0AAA9RXW1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0AAA9RXW1-1", "url": "https://www.uniprot.org/uniprotkb/A0AAA9RXW1-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0AAA9S3H1", "url": "https://www.uniprot.org/uniprotkb/A0AAA9S3H1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0AAA9S3H1-1", "url": "https://www.uniprot.org/uniprotkb/A0AAA9S3H1-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0AAA9SC87", "url": "https://www.uniprot.org/uniprotkb/A0AAA9SC87", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0AAA9SC87-1", "url": "https://www.uniprot.org/uniprotkb/A0AAA9SC87-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0AAA9TEF5", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TEF5", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0AAA9TEF5-1", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TEF5-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0AAA9TVB0", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TVB0", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0AAA9TVB0-1", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TVB0-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "F1MZG7", "url": "https://www.uniprot.org/uniprotkb/F1MZG7", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "F1MZG7-1", "url": "https://www.uniprot.org/uniprotkb/F1MZG7-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MKCTINVMNLNHPQSIPWPHPWKNCLPQNWSLVLVNIVVLRTPEGRKTALGEALWVGSRNLLVRGEAAPSPGLMTRGFAPSLPVEFPKMGSFRRPRPRFMSSPALSDLPRFQAARQALQLSSNSAWNSVQTAVINVFKGGGLQSNELYALNENIRRLLKSELGSFITDYFQNQLLAKGLLFVEEKIKLCEGENRIEVLAEVWDHFFTETLPTLQAIFYPVQGQELTIRQISLLGFRDLVLLKVKLEDLLLLAQPQLPSSIVQMLLILQSVHEPTGPSEGYLQLEELVKQVVSPFLGISEDRGLSGPTYTLARRHSRVRPKVTLLNYASPITPVSRPLNEMALTPLTEQEGEAYLEKCGSVRRHTVANAHSDIQLLAMATMMHSGLGEESGGEDKCLLLQPSFPPPHRQCSSEPNITDGPDEPEQGATGSQEDSELNCASLS", "length": 441, "header": "tr|A0AAA9TVB0-1|A0AAA9TVB0_BOVIN Isoform 1 of Proline rich 5 like OS=Bos taurus OX=9913 GN=PRR5L PE=3 SV=1 CANONICAL=A0AAA9TVB0-1" }, "isoforms": [ { "isoform_ac": "A0A3Q1MWD9-1", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1MWD9/entry", "sequence": { "sequence": "MKPGSPALQQILYHLSYQVLVNIVVLRTPEGRKTALGEALWVGSRNLLVRGEAAPSPGLMTRGFAPSLPVEFPKMGSFRRPRPRFMSSPALSDLPRFQAARQALQLSSNSAWNSVQTAVINVFKGGGLQSNELYALNENIRRLLKSELGSFITDYFQNQLLAKGLLFVEEKIKLCEGENRIEVLAEVWDHFFTETLPTLQAIFYPVQGQELTIRQISLLGFRDLVLLKVKLEDLLLLAQPQLPSSIVQMLLILQSVHEPTGPSEGYLQLEELVKQVVSPFLGISEDRGLSGPTYTLARRHSRVRPKVTLLNYASPITPVSRPLNEMALTPLTEQEGEAYLEKCGSVRRHTVANAHSDIQLLAMATMMHSGLGEESGGEDKCLLLQPSFPPPHRQCSSEPNITDGPDEPEQGATGSQEDSELNCASLS", "length": 427, "header": "tr|A0A3Q1MWD9-1|A0AAA9TVB0_BOVIN Computationally mapped isoform of Proline rich 5 like OS=Bos taurus OX=9913 GN=PRR5L PE=3 SV=1 CANONICAL=A0AAA9TVB0-1" }, "locus": { "chromosome": "15", "start_pos": 66917955, "end_pos": 66852668, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000069244.3", "url": "https://www.ensembl.org/id/ENSBTAT00000069244.3" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000059724.2", "url": "https://www.ensembl.org/id/ENSBTAP00000059724.2" } ] } }, { "isoform_ac": "A0AAA9RXW1-1", "url": "https://www.uniprot.org/uniprotkb/A0AAA9RXW1/entry", "sequence": { "sequence": "MTRGFAPSLPVEFPKMGSFRRPRPRFMSSPALSDLPRFQAARQALQLSSNSAWNSVQTAVINVFKGGGLQSNELYALNENIRRLLKSELGSFITDYFQDPWLVESVNIKDPVKQKTDYKLYADFQNQLLAKGLLFVEEKIKLCEGENRIEVLAEVWDHFFTETLPTLQAIFYPVQGQELTIRQISLLGFRDLVLLKVKLEDLLLLAQPQLPSSIVQMLLILQSVHEPTGPSEGYLQLEELVKQVVSPFLGISEDRGLSGPTYTLARRHSRVRPKVTLLNYASPITPVSRPLNEMALTPLTEQEGEAYLEKCGSVRRHTVANAHSDIQLLAMATMMHSGLGEESGGEDKCLLLQPSFPPPHRQCSSEPNITDGPDEPEQGATGSQEDSELNCASLS", "length": 395, "header": "tr|A0AAA9RXW1-1|A0AAA9TVB0_BOVIN Computationally mapped isoform of Proline rich 5 like OS=Bos taurus OX=9913 GN=PRR5L PE=3 SV=1 CANONICAL=A0AAA9TVB0-1" }, "locus": { "chromosome": "15", "start_pos": 66917955, "end_pos": 66862808, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000104729.2", "url": "https://www.ensembl.org/id/ENSBTAT00000104729.2" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000078372.1", "url": "https://www.ensembl.org/id/ENSBTAP00000078372.1" } ] } }, { "isoform_ac": "A0AAA9S3H1-1", "url": "https://www.uniprot.org/uniprotkb/A0AAA9S3H1/entry", "sequence": { "sequence": "GKRVTSLGPGAPPPPRLWTRAGEDLRLDRTPQSRERREERELGTARWREPSRSLFARGVQTAVINVFKGGGLQSNELYALNENIRRLLKSELGSFITDYFQNQLLAKGLLFVEEKIKLCEGENRIEVLAEVWDHFFTETLPTLQAIFYPVQGQELTIRQISLLGFRDLVLLKVKLEDLLLLAQPQLPSSIVQMLLILQSVHEPTGPSEGYLQLEELVKQVVSPFLGISEDRGLSGPTYTLARRHSRVRPKVTLLNYASPITPVSRPLNEMALTPLTEQEGEAYLEKCGSVRRHTVANAHSDIQLLAMATMMHSGLGEESGGEDKCLLLQPSFPPPHRQCSSEPNITDGPDEPEQGATGSQEDSELNCASLS", "length": 371, "header": "tr|A0AAA9S3H1-1|A0AAA9TVB0_BOVIN Computationally mapped isoform of Proline rich 5 like OS=Bos taurus OX=9913 GN=PRR5L PE=3 SV=1 CANONICAL=A0AAA9TVB0-1" }, "locus": { "chromosome": "15", "start_pos": 66917955, "end_pos": 66840086, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000096421.2", "url": "https://www.ensembl.org/id/ENSBTAT00000096421.2" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000080486.1", "url": "https://www.ensembl.org/id/ENSBTAP00000080486.1" } ] } }, { "isoform_ac": "A0AAA9SC87-1", "url": "https://www.uniprot.org/uniprotkb/A0AAA9SC87/entry", "sequence": { "sequence": "MPGARVLLVSSKAVLVNIVVLRTPEGRKTALGEALWVGSRNLLVRGEAAPSPGLMTRGFAPSLPVEFPKMGSFRRPRPRFMSSPALSDLPRFQAARQALQLSSNSAWNSVQTAVINVFKGGGLQSNELYALNENIRRLLKSELGSFITDYFQNQLLAKGLLFVEEKIKLCEGENRIEVLAEVWDHFFTETLPTLQAIFYPVQGQELTIRQISLLGFRDLVLLKVKLEDLLLLAQPQLPSSIVQMLLILQSVHEPTGPSEGYLQLEELVKQVVSPFLGISEDRGLSGPTYTLARRHSRVRPKVTLLNYASPITPVSRPLNEMALTPLTEQEGEAYLEKCGSVRRHTVANAHSDIQLLAMATMMHSGLGEESGGEDKCLLLQPSFPPPHRQCSSEPNITDGPDEPEQGATGSQEDSELNCASLS", "length": 422, "header": "tr|A0AAA9SC87-1|A0AAA9TVB0_BOVIN Computationally mapped isoform of Proline rich 5 like OS=Bos taurus OX=9913 GN=PRR5L PE=3 SV=1 CANONICAL=A0AAA9TVB0-1" }, "locus": { "chromosome": "15", "start_pos": 66917955, "end_pos": 66841264, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000120735.2", "url": "https://www.ensembl.org/id/ENSBTAT00000120735.2" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000082995.1", "url": "https://www.ensembl.org/id/ENSBTAP00000082995.1" } ] } }, { "isoform_ac": "A0AAA9TEF5-1", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TEF5/entry", "sequence": { "sequence": "MTRGFAPSLPVEFPKMGSFRRPRPRFMSSPALSDLPRFQAARQALQLSSNSAWNSVQTAVINVFKGGGLQSNELYALNENIRRLLKSELGSFITDYFQNQLLAKGLLFVEEKIKLCEGENRIEVLAEVWDHFFTETLPTLQAIFYPVQGQELTIRQISLLGFRDLVLLKVKLEDLLLLAQPQLPSSIVQMLLILQPGATPGSGPRSRS", "length": 208, "header": "tr|A0AAA9TEF5-1|A0AAA9TVB0_BOVIN Computationally mapped isoform of Proline rich 5 like OS=Bos taurus OX=9913 GN=PRR5L PE=3 SV=1 CANONICAL=A0AAA9TVB0-1" }, "locus": { "chromosome": "15", "start_pos": 66917602, "end_pos": 66862808, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000096081.2", "url": "https://www.ensembl.org/id/ENSBTAT00000096081.2" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000094554.1", "url": "https://www.ensembl.org/id/ENSBTAP00000094554.1" } ] } }, { "isoform_ac": "A0AAA9TVB0-1", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TVB0/entry", "sequence": { "sequence": "MKCTINVMNLNHPQSIPWPHPWKNCLPQNWSLVLVNIVVLRTPEGRKTALGEALWVGSRNLLVRGEAAPSPGLMTRGFAPSLPVEFPKMGSFRRPRPRFMSSPALSDLPRFQAARQALQLSSNSAWNSVQTAVINVFKGGGLQSNELYALNENIRRLLKSELGSFITDYFQNQLLAKGLLFVEEKIKLCEGENRIEVLAEVWDHFFTETLPTLQAIFYPVQGQELTIRQISLLGFRDLVLLKVKLEDLLLLAQPQLPSSIVQMLLILQSVHEPTGPSEGYLQLEELVKQVVSPFLGISEDRGLSGPTYTLARRHSRVRPKVTLLNYASPITPVSRPLNEMALTPLTEQEGEAYLEKCGSVRRHTVANAHSDIQLLAMATMMHSGLGEESGGEDKCLLLQPSFPPPHRQCSSEPNITDGPDEPEQGATGSQEDSELNCASLS", "length": 441, "header": "tr|A0AAA9TVB0-1|A0AAA9TVB0_BOVIN Isoform 1 of Proline rich 5 like OS=Bos taurus OX=9913 GN=PRR5L PE=3 SV=1 CANONICAL=A0AAA9TVB0-1" }, "locus": { "chromosome": "15", "start_pos": 66917955, "end_pos": 66853384, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000118996.2", "url": "https://www.ensembl.org/id/ENSBTAT00000118996.2" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000101065.1", "url": "https://www.ensembl.org/id/ENSBTAP00000101065.1" } ] } }, { "isoform_ac": "F1MZG7-1", "url": "https://www.uniprot.org/uniprotkb/F1MZG7/entry", "sequence": { "sequence": "MTRGFAPSLPVEFPKMGSFRRPRPRFMSSPALSDLPRFQAARQALQLSSNSAWNRRLLKSELGSFITDYFQNQLLAKGLLFVEEKIKLCEGENRIEVLAEVWDHFFTETLPTLQAIFYPVQGQELTIRQISLLGFRDLVLLKVKLEDLLLLAQPQLPSSIVQMLLILQSVHEPTGPSEGYLQLEELVKQVVSPFLGISEDRGLSGPTYTLARRHSRVRPKVTLLNYASPITPVSRPLNEMALTPLTEQEGEAYLEKCGSVRRHTVANAHSDIQLLAMATMMHSGLGEESGGEDKCLLLQPSFPPPHRQCSSEPNITDGPDEPEQGATGSQEDSELNCASLS", "length": 341, "header": "tr|F1MZG7-1|A0AAA9TVB0_BOVIN Computationally mapped isoform of Proline rich 5 like OS=Bos taurus OX=9913 GN=PRR5L PE=3 SV=3 CANONICAL=A0AAA9TVB0-1" }, "locus": { "chromosome": "15", "start_pos": 66917955, "end_pos": 66862808, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000028004.8", "url": "https://www.ensembl.org/id/ENSBTAT00000028004.8" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000028004.6", "url": "https://www.ensembl.org/id/ENSBTAP00000028004.6" } ] } } ], "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "other", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 331, "start_aa": "Thr", "end_pos": 331, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr331", "evidence": [ { "id": "", "database": "GlyGen", "url": "https://data.glygen.org/" } ], "filter_code": "000000000000000010000.00000000001000.0.01000" } ], "phosphorylation": [], "glycation": [], "keywords": [ "glycoprotein", "glycoprotein_predicted" ], "publication": [], "pathway": [], "orthologs": [], "go_annotation": { "categories": [ { "name": "Biological Process", "total": 5, "go_terms": [ { "name": "regulation of fibroblast migration", "id": "GO:0010762", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0010762", "evidence": [ { "database": "UniProtKB", "id": "A0AAA9TVB0", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TVB0" } ], "pmid": "" }, { "name": "positive regulation of intracellular protein transport", "id": "GO:0090316", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0090316", "evidence": [ { "database": "UniProtKB", "id": "A0AAA9TVB0", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TVB0" } ], "pmid": "" }, { "name": "cellular response to oxidative stress", "id": "GO:0034599", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0034599", "evidence": [ { "database": "UniProtKB", "id": "A0AAA9TVB0", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TVB0" } ], "pmid": "" }, { "name": "positive regulation of mRNA catabolic process", "id": "GO:0061014", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0061014", "evidence": [ { "database": "UniProtKB", "id": "A0AAA9TVB0", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TVB0" } ], "pmid": "" }, { "name": "TORC2 signaling", "id": "GO:0038203", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0038203", "evidence": [ { "database": "UniProtKB", "id": "A0AAA9TVB0", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TVB0" } ], "pmid": "" } ] }, { "name": "Molecular Function", "total": 1, "go_terms": [ { "name": "ubiquitin protein ligase binding", "id": "GO:0031625", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0031625", "evidence": [ { "database": "UniProtKB", "id": "A0AAA9TVB0", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TVB0" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 1, "go_terms": [ { "name": "TORC2 complex", "id": "GO:0031932", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0031932", "evidence": [ { "database": "UniProtKB", "id": "A0AAA9TVB0", "url": 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"o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 1 }, { "field": "total_sites", "count": 1 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 1 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "exact_sites", "count": 1 }, { "field": "exact_o_linked_sites", "count": 1 }, { "field": "fuzzy_sites", "count": 0 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_pos", "start_aa", "end_pos", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ], "tool_support": { "graph_view": "yes" } }, { "uniprot_canonical_ac": "A0AAA9TT35-1", "uniprot_ac": "A0AAA9TT35", "uniprot_id": "A0AAA9TT35_BOVIN", "mass": { "chemical_mass": 148103.0, "monoisotopic_mass": 148103.0 }, "refseq": { "ac": "XP_024834746", "name": "rho family-interacting cell polarization regulator 1 isoform X1", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_024834746" }, "gene_names": [ { "name": "RIPOR1", "type": "recommended", "evidence": [ { "id": "A0AAA9TT35", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TT35" } ] }, { "name": "RIPOR1", "type": "synonym", "evidence": [ { "id": "XP_024834746", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_024834746" } ] } ], "protein_names": [ { "name": "Rho family-interacting cell polarization regulator 1", "type": "recommended", "evidence": [ { "id": "A0AAA9TT35", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TT35/entry#names_and_taxonomy" } ] }, { "name": "rho family-interacting cell polarization regulator 1 isoform X1", "type": "synonym", "evidence": [ { "id": "XP_024834746", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_024834746" } ] } ], "function": [ { "annotation": "Downstream effector protein for Rho-type small GTPases that plays a role in cell polarity and directional migration. Acts as an adapter protein, linking active Rho proteins to STK24 and STK26 kinases, and hence positively regulates Golgi reorientation in polarized cell migration upon Rho activation. Involved in the subcellular relocation of STK26 from the Golgi to cytoplasm punctae in a Rho- and PDCD10-dependent manner upon serum stimulation.", "evidence": [ { "database": "UniProtKB", "id": "A0AAA9TT35", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TT35#function" }, { "database": "UniProtKB", "id": "ARBA00054594", "url": "https://www.uniprot.org/uniprotkb/ARBA00054594#function" }, { "database": "UniProtKB", "id": "A0A3Q1N996", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1N996#function" }, { "database": "UniProtKB", "id": "A0AAA9S975", "url": "https://www.uniprot.org/uniprotkb/A0AAA9S975#function" }, { "database": "UniProtKB", "id": "F1MYQ3", "url": "https://www.uniprot.org/uniprotkb/F1MYQ3#function" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Bos taurus", "taxid": 9913, "evidence": [ { "database": "UniProtKB", "id": "A0AAA9TT35", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TT35" } ], "common_name": "Bovine", "glygen_name": "Bovine", "reference_species": "Bos taurus [9913]" } ], "gene": [ { "name": "RIPOR1", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TT35", "locus": { "chromosome": "18", "start_pos": 35131626, "end_pos": 35092078, "strand": "-", "evidence": [ { "database": "Ensembl Gene", "id": "ENSBTAG00000008860", "url": "https://www.ensembl.org/id/ENSBTAG00000008860" } ] } } ], "crossref": [ { "id": "ENSBTAG00000008860", "url": "https://bgee.org/?page=gene&gene_id=ENSBTAG00000008860", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "100336872", "url": "https://www.ncbi.nlm.nih.gov/gene/100336872", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR011989", "url": "https://www.ebi.ac.uk/interpro/entry/IPR011989", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR016024", "url": "https://www.ebi.ac.uk/interpro/entry/IPR016024", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR026136", "url": "https://www.ebi.ac.uk/interpro/entry/IPR026136", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR031780", "url": "https://www.ebi.ac.uk/interpro/entry/IPR031780", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "bta:100336872", "url": "https://www.genome.jp/dbget-bin/www_bget?bta:100336872", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "PTHR15829", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR15829", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR15829:SF1", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR15829:SF1", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF15903", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF15903", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "XP_024834746", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_024834746", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A3Q1N996", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1N996", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A3Q1N996-1", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1N996-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0AAA9S975", "url": "https://www.uniprot.org/uniprotkb/A0AAA9S975", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0AAA9S975-1", "url": "https://www.uniprot.org/uniprotkb/A0AAA9S975-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0AAA9TT35", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TT35", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0AAA9TT35-1", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TT35-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "F1MYQ3", "url": "https://www.uniprot.org/uniprotkb/F1MYQ3", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "F1MYQ3-1", "url": "https://www.uniprot.org/uniprotkb/F1MYQ3-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MSAKKRGSPARTHSMMSLSVRPQRRLLSARVSRSQSFAGVLGSQERGPRSFPAFSPPGPPRKPPALSRVSKMFSVAHPAPKVPQPERLDLVYTALKRGLTAYLEVHQQEQEKLQGQIRESKRNSRLGFLYDLDKQVKSIERFLRRLEFHASKVLVRHTCVCLQLGVGGRVSQGEWVMVGPGEGPGGATPAVSLSPHLPPDSSAQIDELYESYCVQRRLRDGAYNMVRAYSTGSPGSREARDSLAEATRGHREYTESMCLLESELEAQLGEFHLRMKGLAGFARLCVGDQYEIYMKYGRQRWKLRGRIESSGKQVWDSEETVFLPLLTEFLSIKVTELKGLANHVVVGSVSCETKDLFAALPQVVAVDINDLGTIKLSLEVTWSPFDKDDQPSAASTVNKASTVTKRFSTYSQSPPDTPSLREQAFYNMLRRQEELENGTAWSLSSESSDDSSSPQLSGTARHSSAPRPLVQQPEPLPIQVAFHRAETSTSGPMDEEGAVAPALANGHAPYSRTLSHISEASVDAALAEASVEAADLESLVRGPSPPACPDPTHGEHPARVPPVLDAGHSATNPTLSTTGPAPSAHLGSANKTINSSSPELPTQTTTGSTYCAMSPTHSAPSLIHCTTASTHKTVVSILTTTGPTPSTTGPVQTTSPTHKPVLSTLTPAAPTPNATDPVQTTASLSHTVTNLTHTVTSATNKPMASTLMTAGPTASATGPVQTTTSPTHTTTSPTHTVASPTHATASPTYTTTGPTHTTASPTYTTTGSTHTTASPTYTTTGPTHTTASPTHTTTGPTHTTATTTPKAKMSTNTTTPNAKDPVQTTSSPTHSVTSPTLITVSSSTFLDFAKLSSPSANTDPPHLGTDPLSGSYLASTPCTQADPISPSTSHPSPACSSWEPLTTPSPDPSEAIRQSPSLPPSPLAPVPQHPDPKVARATPAPVPGAAGGAGDRRLEEALGALMAALDDYRGQFPELQGLEQEVTRLESLLMQRQGLTRSRASSLSITVEHALESFSFLNEDEDEDNDSPGDRPPNSLAPGAEDSLDSPSARPLSTECPALDAALVQHLYHCSRLLLKLGTFGPLRCQEAWALERLLREARVLEAVCELSRRWEIPATSAQEVVQFSASRPGFLTFWDQCTEGFSPFICPVERVLLTFCNQYSARLSLRQPGLAEAVCVKFLEDALGQKLPRNQAGPGEQLTVFQFWSYVEALDCSSMEAYVTETAEEVLLVRNLNSDDQAIVLKALRLAPEGRLQRDGLRALSSLLVHGNNKVMAAVSTQLRSLSLGPAFRERALLCFLDQLEDEDVQTRVAGCLALGCIKAPEGIEPLVYLCQTDTEAVREAARQSLQQCGEEGQSAHRRLEESLDALPHIFGPGSMASTAF", "length": 1382, "header": "tr|A0AAA9TT35-1|A0AAA9TT35_BOVIN Isoform 1 of Rho family-interacting cell polarization regulator 1 OS=Bos taurus OX=9913 GN=RIPOR1 PE=3 SV=1 CANONICAL=A0AAA9TT35-1" }, "isoforms": [ { "isoform_ac": "A0A3Q1N996-1", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1N996/entry", "sequence": { "sequence": "MKGSPARTHSMMSLSVRPQRRLLSARVSRSQSFAGVLGSQERGPRSFPAFSPPGPPRKPPALSRVSKMFSVAHPAPKVPQPERLDLVYTALKRGLTAYLEVHQQEQEKLQGQIRESKRNSRLGFLYDLDKQVKSIERFLRRLEFHASKIDELYESYCVQRRLRDGAYNMVRAYSTGSPGSREARDSLAEATRGHREYTESMCLLESELEAQLGEFHLRMKGLAGFARLCVGDQYEIYMKYGRQRWKLRGRIESSGKQVWDSEETVFLPLLTEFLSIKVTELKGLANHVVVGSVSCETKDLFAALPQVVAVDINDLGTIKLSLEVTWSPFDKDDQPSAASTVNKASTVTKRFSTYSQSPPDTPSLREQAFYNMLRRQEELENGTAWSLSSESSDDSSSPQLSGTARHSSAPRPLVQQPEPLPIQVAFHRAETSTSGPMDEEGAVAPALANGHAPYSRTLSHISEASVDAALAEASVEAADLESLVRGPSPPACPDPTHGEHPARVPPVLDAGHSATNPTLSTTGPAPSAHLGSANKTINSSSPELPTQTTTGSTYCAMSPTHSAPSLIHCTTASTHKTVVSILTTTGPTPSTTGPVQTTSPTHKPVLSTLTPAAPTPNATDPVQTTASLSHTVTNLTHTVTSATNKPMASTLMTAGPTASATGPVQTTTSPTHTTTSPTHTVASPTHATASPTYTTTGPTHTTASPTYTTTGSTHTTASPTYTTTGPTHTTASPTHTTTGPTHTTATTTPKAKMSTNTTTPNAKDPVQTTSSPTHSVTSPTLITVSSSTFLDFAKLSSPSANTDPPHLGTDPLSGSYLASTPCTQADPISPSTSHPSPACSSWEPLTTPSPDPSEAIRQSPSLPPSPLAPVPQHPDPKVARATPAPVPGAAGGAGDRRLEEALGALMAALDDYRGQFPELQGLEQEVTRLESLLMQRQGLTRSRASSLSITVEHALESFSFLNEDEDEDNDSPGDRPPNSLAPGAEDSLDSPSARPLSTECPALDAALVQHLYHCSRLLLKLGTFGPLRCQEAWALERLLREARVLEAVCELSRRWEIPATSAQEVVQFSASRPGFLTFWDQCTEGFSPFICPVERVLLTFCNQYSARLSLRQPGLAEAVCVKFLEDALGQKLPRNQAGPGEQLTVFQFWSYVEALDCSSMEAYVTETAEEVLLVRNLNSDDQAIVLKALRLAPEGRLQRDGLRALSSLLVHGNNKVMAAVSTQLRSLSLGPAFRERALLCFLDQLEDEDVQTRVAGCLALGCIKAPEGIEPLVYLCQTDTEAVREAARQSLQQCGEEGQSAHRRLEESLDALPHIFGPGSMASTAF", "length": 1326, "header": "tr|A0A3Q1N996-1|A0AAA9TT35_BOVIN Computationally mapped isoform of Rho family-interacting cell polarization regulator 1 OS=Bos taurus OX=9913 GN=RIPOR1 PE=3 SV=3 CANONICAL=A0AAA9TT35-1" }, "locus": { "chromosome": "18", "start_pos": 35131094, "end_pos": 35115930, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000075639.3", "url": "https://www.ensembl.org/id/ENSBTAT00000075639.3" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000067708.3", "url": "https://www.ensembl.org/id/ENSBTAP00000067708.3" } ] } }, { "isoform_ac": "A0AAA9S975-1", "url": "https://www.uniprot.org/uniprotkb/A0AAA9S975/entry", "sequence": { "sequence": "MMSLSVRPQRRLLSARVSRSQSFAGVLGSQERGPRSFPAFSPPGPPRKPPALSRVSKMFSVAHPAPKVPQPERLDLVYTALKRGLTAYLEVHQQEQEKLQGQIRESKRNSRLGFLYDLDKQVKSIERFLRRLEFHASKIDELYESYCVQRRLRDGAYNMVRAYSTGSPGSREARDSLAEATRGHREYTESMCLLESELEAQLGEFHLRMKGLAGFARLCVGDQYEIYMKYGRQRWKLRGRIESSGKQVWDSEETVFLPLLTEFLSIKVTELKGLANHVVVGSVSCETKDLFAALPQVVAVDINDLGTIKLSLEVTWSPFDKDDQPSAASTVNKASTVTKRFSTYSQSPPDTPSLREQAFYNMLRRQEELENGTAWSLSSESSDDSSSPQLSGTARHSSAPRPLVQQPEPLPIQVAFHRAETSTSGPMDEEGAVAPALANGHAPYSRTLSHISEASVDAALAEASVEAADLESLVRGPSPPACPDPTHGEHPARVPPVLDAGHSATNPTLSTTGPAPSAHLGSANKTINSSSPELPTQTTTGSTYCAMSPTHSAPSLIHCTTASTHKTVVSILTTTGPTPSTTGPVQTTSPTHKPVLSTLTPAAPTPNATDPVQTTASLSHTVTNLTHTVTSATNKPMASTLMTAGPTASATGPVQTTTSPTHTTTSPTHTVASPTHATASPTYTTTGPTHTTASPTYTTTGSTHTTASPTYTTTGPTHTTATTTPKAKMSTNTTTPNAKDPVQTTSSPTHSVTSPTLITVSSSTFLDFAKLSSPSANTDPPHLGTDPLSGSYLASTPCTQADPISPSTSHPSPACSSWEPLTTPSPDPSEAIRQSPSLPPSPLAPVPQHPDPKVARATPAPVPGAAGGAGDRRLEEALGALMAALDDYRGQFPELQGLEQEVTRLESLLMQRQGLTRSRASSLSITVEHALESFSFLNEDEDEDNDSPGDRPPNSLAPGAEDSLDSPSARPLSTECPALDAALVQHLYHCSRLLLKLGTFGPLRCQEAWALERLLREARVLEAVCELSRRWEIPATSAQEVVQFSASRPGFLTFWDQCTEGFSPFICPVERVLLTFCNQYSARLSLRQPGLAEAVCVKFLEDALGQKLPRNQAGPGEQLTVFQFWSYVEALDCSSMEAYVTETAEEVLLVRNLNSDDQAIVLKALRLAPEGRLQRDGLRALSSLLVHGNNKVMAAVSTQLRSLSLGPAFRERALLCFLDQLEDEDVQTRVAGCLALGCIKAPEGIEPLVYLCQTDTEAVREAARQSLQQCGEEGQSAHRRLEESLDALPHIFGPGSMASTAF", "length": 1302, "header": "tr|A0AAA9S975-1|A0AAA9TT35_BOVIN Computationally mapped isoform of Rho family-interacting cell polarization regulator 1 OS=Bos taurus OX=9913 GN=RIPOR1 PE=3 SV=1 CANONICAL=A0AAA9TT35-1" }, "locus": { "chromosome": "18", "start_pos": 35131094, "end_pos": 35122987, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000094861.2", "url": "https://www.ensembl.org/id/ENSBTAT00000094861.2" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000078691.1", "url": "https://www.ensembl.org/id/ENSBTAP00000078691.1" } ] } }, { "isoform_ac": "A0AAA9TT35-1", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TT35/entry", "sequence": { "sequence": "MSAKKRGSPARTHSMMSLSVRPQRRLLSARVSRSQSFAGVLGSQERGPRSFPAFSPPGPPRKPPALSRVSKMFSVAHPAPKVPQPERLDLVYTALKRGLTAYLEVHQQEQEKLQGQIRESKRNSRLGFLYDLDKQVKSIERFLRRLEFHASKVLVRHTCVCLQLGVGGRVSQGEWVMVGPGEGPGGATPAVSLSPHLPPDSSAQIDELYESYCVQRRLRDGAYNMVRAYSTGSPGSREARDSLAEATRGHREYTESMCLLESELEAQLGEFHLRMKGLAGFARLCVGDQYEIYMKYGRQRWKLRGRIESSGKQVWDSEETVFLPLLTEFLSIKVTELKGLANHVVVGSVSCETKDLFAALPQVVAVDINDLGTIKLSLEVTWSPFDKDDQPSAASTVNKASTVTKRFSTYSQSPPDTPSLREQAFYNMLRRQEELENGTAWSLSSESSDDSSSPQLSGTARHSSAPRPLVQQPEPLPIQVAFHRAETSTSGPMDEEGAVAPALANGHAPYSRTLSHISEASVDAALAEASVEAADLESLVRGPSPPACPDPTHGEHPARVPPVLDAGHSATNPTLSTTGPAPSAHLGSANKTINSSSPELPTQTTTGSTYCAMSPTHSAPSLIHCTTASTHKTVVSILTTTGPTPSTTGPVQTTSPTHKPVLSTLTPAAPTPNATDPVQTTASLSHTVTNLTHTVTSATNKPMASTLMTAGPTASATGPVQTTTSPTHTTTSPTHTVASPTHATASPTYTTTGPTHTTASPTYTTTGSTHTTASPTYTTTGPTHTTASPTHTTTGPTHTTATTTPKAKMSTNTTTPNAKDPVQTTSSPTHSVTSPTLITVSSSTFLDFAKLSSPSANTDPPHLGTDPLSGSYLASTPCTQADPISPSTSHPSPACSSWEPLTTPSPDPSEAIRQSPSLPPSPLAPVPQHPDPKVARATPAPVPGAAGGAGDRRLEEALGALMAALDDYRGQFPELQGLEQEVTRLESLLMQRQGLTRSRASSLSITVEHALESFSFLNEDEDEDNDSPGDRPPNSLAPGAEDSLDSPSARPLSTECPALDAALVQHLYHCSRLLLKLGTFGPLRCQEAWALERLLREARVLEAVCELSRRWEIPATSAQEVVQFSASRPGFLTFWDQCTEGFSPFICPVERVLLTFCNQYSARLSLRQPGLAEAVCVKFLEDALGQKLPRNQAGPGEQLTVFQFWSYVEALDCSSMEAYVTETAEEVLLVRNLNSDDQAIVLKALRLAPEGRLQRDGLRALSSLLVHGNNKVMAAVSTQLRSLSLGPAFRERALLCFLDQLEDEDVQTRVAGCLALGCIKAPEGIEPLVYLCQTDTEAVREAARQSLQQCGEEGQSAHRRLEESLDALPHIFGPGSMASTAF", "length": 1382, "header": "tr|A0AAA9TT35-1|A0AAA9TT35_BOVIN Isoform 1 of Rho family-interacting cell polarization regulator 1 OS=Bos taurus OX=9913 GN=RIPOR1 PE=3 SV=1 CANONICAL=A0AAA9TT35-1" }, "locus": { "chromosome": "18", "start_pos": 35131094, "end_pos": 35122143, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000132888.2", "url": "https://www.ensembl.org/id/ENSBTAT00000132888.2" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000100503.1", "url": "https://www.ensembl.org/id/ENSBTAP00000100503.1" } ] } }, { "isoform_ac": "F1MYQ3-1", "url": "https://www.uniprot.org/uniprotkb/F1MYQ3/entry", "sequence": { "sequence": "MMSLSVRPQRRLLSARVSRSQSFAGVLGSQERGPRSFPAFSPPGPPRKPPALSRVSKMFSVAHPAPKVPQPERLDLVYTALKRGLTAYLEVHQQEQEKLQGQIRESKRNSRLGFLYDLDKASNTPFPQQVKSIERFLRRLEFHASKIDELYESYCVQRRLRDGAYNMVRAYSTGSPGSREARDSLAEATRGHREYTESMCLLESELEAQLGEFHLRMKGLAGFARLCVGDQYEIYMKYGRQRWKLRGRIESSGKQVWDSEETVFLPLLTEFLSIKVTELKGLANHVVVGSVSCETKDLFAALPQVVAVDINDLGTIKLSLEVTWSPFDKDDQPSAASTVNKASTVTKRFSTYSQSPPDTPSLREQAFYNMLRRQEELENGTAWSLSSESSDDSSSPQLSGTARHSSAPRPLVQQPEPLPIQVAFHRAETSTSGPMDEEGAVAPALANGHAPYSRTLSHISEASVDAALAEASVEAADLESLVRGPSPPACPDPTHGEHPARVPPVLDAGHSATNPTLSTTGPAPSAHLGSANKTINSSSPELPTQTTTGSTYCAMSPTHSAPSLIHCTTASTHKTVVSILTTTGPTPSTTGPVQTTSPTHKPVLSTLTPAAPTPNATDPVQTTASLSHTVTNLTHTVTSATNKPMASTLMTAGPTASATGPVQTTTSPTHTTTSPTHTVASPTHATASPTYTTTGPTHTTASPTYTTTGSTHTTASPTYTTTGPTHTTASPTHTTTGPTHTTATTTPKAKMSTNTTTPNAKDPVQTTSSPTHSVTSPTLITVSSSTFLDFAKLSSPSANTDPPHLGTDPLSGSYLASTPCTQADPISPSTSHPSPACSSWEPLTTPSPDPSEAIRQSPSLPPSPLAPVPQHPDPKVARATPAPVPGAAGGAGDRRLEEALGALMAALDDYRGQFPELQGLEQEVTRLESLLMQRQGLTRSRASSLSITVEHALESFSFLNEDEDEDNDSPGDRPPNSLAPGAEDSLDSPSARPLSTECPALDAALVQHLYHCSRLLLKLGTFGPLRCQEAWALERLLREARVLEAVCELSRRWEIPATSAQEVVQFSASRPGFLTFWDQCTEGFSPFICPVERVLLTFCNQYSARLSLRQPGLAEAVCVKFLEDALGQKLPRNQAGPGEQLTVFQFWSYVEALDCSSMEAYVTETAEEVLLVRNLNSDDQAIVLKALRLAPEGRLQRDGLRALSSLLVHGNNKVMAAVSTQLRSLSLGPAFRERALLCFLDQLEDEDVQTRVAGCLALGCIKAPEGIEPLVYLCQTDTEAVREAARQSLQQCGEEGQSAHRRLEESLDALPHIFGPGSMASTAF", 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"categories": [ "Protein Classification" ] }, { "id": "PF00777", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00777", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "18021", "url": "https://www.rhea-db.org/rhea/18021", "database": "Rhea", "categories": [ "Enzyme and Pathway" ] }, { "id": "18913", "url": "https://www.rhea-db.org/rhea/18913", "database": "Rhea", "categories": [ "Enzyme and Pathway" ] }, { "id": "21616", "url": "https://www.rhea-db.org/rhea/21616", "database": "Rhea", "categories": [ "Enzyme and Pathway" ] }, { "id": "47560", "url": "https://www.rhea-db.org/rhea/47560", "database": "Rhea", "categories": [ "Enzyme and Pathway" ] }, { "id": "47588", "url": "https://www.rhea-db.org/rhea/47588", "database": "Rhea", "categories": [ "Enzyme and Pathway" ] }, { "id": "52316", "url": "https://www.rhea-db.org/rhea/52316", "database": "Rhea", "categories": [ "Enzyme and Pathway" ] }, { "id": "52380", "url": 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"UniProtKB", "categories": [ "Protein" ] }, { "id": "A0AAA9TT54", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TT54", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0AAA9TT54-1", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TT54-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0AAA9U1T6", "url": "https://www.uniprot.org/uniprotkb/A0AAA9U1T6", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0AAA9U1T6-1", "url": "https://www.uniprot.org/uniprotkb/A0AAA9U1T6-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0AAF6DLN4", "url": "https://www.uniprot.org/uniprotkb/A0AAF6DLN4", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0AAF6DLN4-1", "url": "https://www.uniprot.org/uniprotkb/A0AAF6DLN4-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MGVRLPGPGPGEPPPATLSVVVLRGSDPVGEGGPGLPGPGPQPLQRLVALHPASINNQTLSAPCGCPCSYPNRVARGSRDDNSPQEPWHLRNMISKSRWKLLAMLALFLAVMVWYSISREDRYIELFYFPVPGKKEPCLQGEAEKMVSKLFGNYSREQPFFLQLKDYFWVKTPSLYELPYGTKGSEDLLLRVLAITSYSIPESIQSLKCRRCVVVGNGHRLRNSSLGEAINKYDVVIRLNSAPVAGYEQDVGSKTTMRLFYPESAHFNPKVEDNPDTLLVLVAFKAMDFHWIESILSDKKRVRKGFWKQPPLIWDVNPKQIRILNPFYMEIAADKLLSLPIHQPHKIKQKPTTGLLAITLALHLCDLVHIAGFGYPDAHQKKQSIHYYEYITLKSMMWSGHNVSQEALAIKRMLEIGAVKNLTYF", "length": 425, "header": "tr|A0AAA9TT54-1|A0AAA9TT54_BOVIN Isoform 1 of CMP-N-acetylneuraminate-beta-galactosamide-alpha-2,3-sialyltransferase 4 OS=Bos taurus OX=9913 GN=ST3GAL4 PE=3 SV=1 CANONICAL=A0AAA9TT54-1" }, "isoforms": [ { "isoform_ac": "A0A3Q1M6Q2-1", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1M6Q2/entry", "sequence": { "sequence": "MEVTCTEAQVARGSRDDNSPQEPWHLRNMISKSRWKLLAMLALFLAVMVWYSISREDRYIELFYFPVPGKKEPCLQGEAEKMVSKLFGNYSREQPFFLQLKDYFWVKTPSLYELPYGTKGSEDLLLRVLAITSYSIPESIQSLKCRRCVVVGNGHRLRNSSLGEAINKYDVVIRLNSAPVAGYEQDVGSKTTMRLFYPESAHFNPKVEDNPDTLLVLVAFKAMDFHWIESILSDKKRVRKGFWKQPPLIWDVNPKQIRILNPFYMEIAADKLLSLPIHQPHKIKQKPTTGLLAITLALHLCDLVHIAGFGYPDAHQKKQSIHYYEYITLKSMMWSGHNVSQEALAIKRMLEIGAVKNLTYF", "length": 361, "header": "tr|A0A3Q1M6Q2-1|A0A3Q1M6Q2_BOVIN Computationally mapped isoform of CMP-N-acetylneuraminate-beta-galactosamide-alpha-2,3-sialyltransferase 4 OS=Bos taurus OX=9913 GN=ST3GAL4 PE=3 SV=2 CANONICAL=A0AAA9TT54-1" }, "locus": { "chromosome": "29", "start_pos": 29738535, "end_pos": 29700234, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000077201.2", "url": "https://www.ensembl.org/id/ENSBTAT00000077201.2" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000065690.2", "url": "https://www.ensembl.org/id/ENSBTAP00000065690.2" } ] } }, { "isoform_ac": "A0AAA9RT99-1", "url": "https://www.uniprot.org/uniprotkb/A0AAA9RT99/entry", "sequence": { "sequence": "MGEDSALAEGAQLAPEAVARGSRDDNSPQEPWHLRNMISKSRWKLLAMLALFLAVMVWYSISREDRYIELFYFPVPGKKEPCLQGEAEKMVSKLFGNYSREQPFFLQLKDYFWVKTPSLYELPYGTKGSEDLLLRVLAITSYSIPESIQSLKCRRCVVVGNGHRLRNSSLGEAINKYDVVIRLNSAPVAGYEQDVGSKTTMRLFYPESAHFNPKVEDNPDTLLVLVAFKAMDFHWIESILSDKKRVRKGFWKQPPLIWDVNPKQIRILNPFYMEIAADKLLSLPIHQPHKIKQKPTTGLLAITLALHLCDLVHIAGFGYPDAHQKKQSIHYYEYITLKSMMWSGHNVSQEALAIKRMLEIGAVKNLTYF", "length": 369, "header": "tr|A0AAA9RT99-1|A0AAA9TT54_BOVIN Computationally mapped isoform of CMP-N-acetylneuraminate-beta-galactosamide-alpha-2,3-sialyltransferase 4 OS=Bos taurus OX=9913 GN=ST3GAL4 PE=3 SV=1 CANONICAL=A0AAA9TT54-1" }, "locus": { "chromosome": "29", "start_pos": 29738535, "end_pos": 29709567, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000095877.1", "url": "https://www.ensembl.org/id/ENSBTAT00000095877.1" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000076110.1", "url": "https://www.ensembl.org/id/ENSBTAP00000076110.1" } ] } }, { "isoform_ac": "A0AAA9TIA8-1", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TIA8/entry", "sequence": { "sequence": "MQCVQWTQRPGGEVARGSRDDNSPQEPWHLRNMISKSRWKLLAMLALFLAVMVWYSISREDRYIELFYFPVPGKKEPCLQGEAEKMVSKLFGNYSREQPFFLQLKDYFWVKTPSLYELPYGTKGSEDLLLRVLAITSYSIPESIQSLKCRRCVVVGNGHRLRNSSLGEAINKYDVVIRLNSAPVAGYEQDVGSKTTMRLFYPESAHFNPKVEDNPDTLLVLVAFKAMDFHWIESILSDKKRVRKGFWKQPPLIWDVNPKQIRILNPFYMEIAADKLLSLPIHQPHKIKQKPTTGLLAITLALHLCDLVHIAGFGYPDAHQKKQSIHYYEYITLKSMMWSGHNVSQEALAIKRMLEIGAVKNLTYF", "length": 365, "header": "tr|A0AAA9TIA8-1|A0AAA9TT54_BOVIN Computationally mapped isoform of CMP-N-acetylneuraminate-beta-galactosamide-alpha-2,3-sialyltransferase 4 OS=Bos taurus OX=9913 GN=ST3GAL4 PE=3 SV=1 CANONICAL=A0AAA9TT54-1" }, "locus": { "chromosome": "29", "start_pos": 29738535, "end_pos": 29710699, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000108202.1", "url": "https://www.ensembl.org/id/ENSBTAT00000108202.1" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000096836.1", "url": "https://www.ensembl.org/id/ENSBTAP00000096836.1" } ] } }, { "isoform_ac": "A0AAA9TT54-1", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TT54/entry", "sequence": { "sequence": "MGVRLPGPGPGEPPPATLSVVVLRGSDPVGEGGPGLPGPGPQPLQRLVALHPASINNQTLSAPCGCPCSYPNRVARGSRDDNSPQEPWHLRNMISKSRWKLLAMLALFLAVMVWYSISREDRYIELFYFPVPGKKEPCLQGEAEKMVSKLFGNYSREQPFFLQLKDYFWVKTPSLYELPYGTKGSEDLLLRVLAITSYSIPESIQSLKCRRCVVVGNGHRLRNSSLGEAINKYDVVIRLNSAPVAGYEQDVGSKTTMRLFYPESAHFNPKVEDNPDTLLVLVAFKAMDFHWIESILSDKKRVRKGFWKQPPLIWDVNPKQIRILNPFYMEIAADKLLSLPIHQPHKIKQKPTTGLLAITLALHLCDLVHIAGFGYPDAHQKKQSIHYYEYITLKSMMWSGHNVSQEALAIKRMLEIGAVKNLTYF", "length": 425, "header": "tr|A0AAA9TT54-1|A0AAA9TT54_BOVIN Isoform 1 of CMP-N-acetylneuraminate-beta-galactosamide-alpha-2,3-sialyltransferase 4 OS=Bos taurus OX=9913 GN=ST3GAL4 PE=3 SV=1 CANONICAL=A0AAA9TT54-1" }, "locus": { "chromosome": "29", "start_pos": 29738535, "end_pos": 29708131, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000095662.1", "url": "https://www.ensembl.org/id/ENSBTAT00000095662.1" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000101803.1", "url": "https://www.ensembl.org/id/ENSBTAP00000101803.1" } ] } }, { "isoform_ac": "A0AAA9U1T6-1", "url": "https://www.uniprot.org/uniprotkb/A0AAA9U1T6/entry", "sequence": { "sequence": "MVTDPRPPFQLPGGPGASIRPLPSKREACGGFLPGVSPLPRRREWGTAALAVPGSVWIWFDNKAPSVARGSRDDNSPQEPWHLRNMISKSRWKLLAMLALFLAVMVWYSISREDRYIELFYFPVPGKKEPCLQGEAEKMVSKLFGNYSREQPFFLQLKDYFWVKTPSLYELPYGTKGSEDLLLRVLAITSYSIPESIQSLKCRRCVVVGNGHRLRNSSLGEAINKYDVVIRLNSAPVAGYEQDVGSKTTMRLFYPESAHFNPKVEDNPDTLLVLVAFKAMDFHWIESILSDKKRVRKGFWKQPPLIWDVNPKQIRILNPFYMEIAADKLLSLPIHQPHKIKQKPTTGLLAITLALHLCDLVHIAGFGYPDAHQKKQSIHYYEYITLKSMMWSGHNVSQEALAIKRMLEIGAVKNLTYF", "length": 418, "header": "tr|A0AAA9U1T6-1|A0AAA9U1T6_BOVIN Computationally mapped isoform of CMP-N-acetylneuraminate-beta-galactosamide-alpha-2,3-sialyltransferase 4 OS=Bos taurus OX=9913 GN=ST3GAL4 PE=3 SV=1 CANONICAL=A0AAA9TT54-1" }, "locus": { "chromosome": "29", "start_pos": 29738535, "end_pos": 29707532, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000102615.1", "url": "https://www.ensembl.org/id/ENSBTAT00000102615.1" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000103834.1", "url": "https://www.ensembl.org/id/ENSBTAP00000103834.1" } ] } }, { "isoform_ac": "A0AAF6DLN4-1", "url": "https://www.uniprot.org/uniprotkb/A0AAF6DLN4/entry", "sequence": { "sequence": "MLPLKQPPPLPSPVHLGSEGLDVVTQPESTRAAGGLLDHLVAPALTRVARGSRDDNSPQEPWHLRNMISKSRWKLLAMLALFLAVMVWYSISREDRYIELFYFPVPGKKEPCLQGEAEKMVSKLFGNYSREQPFFLQLKDYFWVKTPSLYELPYGTKGSEDLLLRVLAITSYSIPESIQSLKCRRCVVVGNGHRLRNSSLGEAINKYDVVIRLNSAPVAGYEQDVGSKTTMRLFYPESAHFNPKVEDNPDTLLVLVAFKAMDFHWIESILSDKKRVRKGFWKQPPLIWDVNPKQIRILNPFYMEIAADKLLSLPIHQPHKIKQKPTTGLLAITLALHLCDLVHIAGFGYPDAHQKKQSIHYYEYITLKSMMWSGHNVSQEALAIKRMLEIGAVKNLTYF", "length": 399, "header": "tr|A0AAF6DLN4-1|A0AAF6DLN4_BOVIN Computationally mapped isoform of CMP-N-acetylneuraminate-beta-galactosamide-alpha-2,3-sialyltransferase 4 OS=Bos taurus OX=9913 GN=ST3GAL4 PE=3 SV=1 CANONICAL=A0AAA9TT54-1" }, "locus": { "chromosome": "29", "start_pos": 29738535, "end_pos": 29729166, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000047405.5", "url": "https://www.ensembl.org/id/ENSBTAT00000047405.5" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000044614.4", "url": "https://www.ensembl.org/id/ENSBTAP00000044614.4" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [ "enzyme" ], "publication": [], "pathway": [], "orthologs": [], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 2, "go_terms": [ { "name": "Golgi membrane", "id": "GO:0000139", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000139", "evidence": [ { "database": "UniProtKB", "id": "A0AAA9TT54", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TT54" } ], "pmid": "" }, { "name": "Golgi cisterna membrane", "id": "GO:0032580", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0032580", "evidence": [ { "database": "UniProtKB", "id": "A0AAA9TT54", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TT54" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 9, "go_terms": [ { "name": "lipid metabolic process", "id": "GO:0006629", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006629", "evidence": [ { "database": "UniProtKB", "id": "A0AAA9TT54", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TT54" } ], "pmid": "" }, { "name": "glycoprotein biosynthetic process", "id": "GO:0009101", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0009101", "evidence": [ { "database": "UniProtKB", "id": "A0AAA9TT54", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TT54" } ], "pmid": "" }, { "name": "positive regulation of leukocyte tethering or rolling", "id": "GO:1903238", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:1903238", "evidence": [ { "database": "UniProtKB", "id": "A0AAA9TT54", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TT54" } ], "pmid": "" }, { "name": "cognition", "id": "GO:0050890", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0050890", "evidence": [ { "database": "UniProtKB", "id": "A0AAA9TT54", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TT54" } ], "pmid": "" }, { "name": "glycolipid biosynthetic process", "id": "GO:0009247", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0009247", "evidence": [ { "database": "UniProtKB", "id": "A0AAA9TT54", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TT54" } ], "pmid": "" }, { "name": "protein N-linked glycosylation", "id": "GO:0006487", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006487", "evidence": [ { "database": "UniProtKB", "id": "A0AAA9TT54", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TT54" } ], "pmid": "" }, { "name": "positive regulation of blood coagulation", "id": "GO:0030194", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030194", "evidence": [ { "database": "UniProtKB", "id": "A0AAA9TT54", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TT54" } ], "pmid": "" }, { "name": "oligosaccharide biosynthetic process", "id": "GO:0009312", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0009312", "evidence": [ { "database": "UniProtKB", "id": "A0AAA9TT54", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TT54" } ], "pmid": "" }, { "name": "sialylation", "id": "GO:0097503", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0097503", "evidence": [ { "database": "UniProtKB", "id": "A0AAA9TT54", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TT54" } ], "pmid": "" } ] }, { "name": "Molecular Function", "total": 3, "go_terms": [ { "name": "beta-D-galactosyl-(1->3)-N-acetyl-beta-D-galactosaminide alpha-2,3- sialyltransferase", "id": "GO:0047288", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0047288", "evidence": [ { "database": "UniProtKB", "id": "A0AAA9TT54", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TT54" } ], "pmid": "" }, { "name": "beta-galactoside (CMP) alpha-2,3-sialyltransferase activity", "id": "GO:0003836", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003836", "evidence": [ { "database": "UniProtKB", "id": "A0AAA9TT54", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TT54" } ], "pmid": "" }, { "name": "N-acetyllactosaminide alpha-2,3-sialyltransferase activity", "id": "GO:0008118", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008118", "evidence": [ { "database": "UniProtKB", "id": "A0AAA9TT54", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TT54" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 153, "end_pos": 155, "annotation": "n_glycosylation_sequon" }, { "start_pos": 223, "end_pos": 225, "annotation": "n_glycosylation_sequon" }, { "start_pos": 402, "end_pos": 404, "annotation": "n_glycosylation_sequon" }, { "start_pos": 421, "end_pos": 423, "annotation": "n_glycosylation_sequon" }, { "start_pos": 57, "end_pos": 59, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [ { "id": "18021", "name": "", "equation": "a ganglioside GM1 (d18:1(4E)) + CMP-N-acetyl-beta-neuraminate = a ganglioside GD1a (d18:1(4E)) + CMP + H(+)", "summary": "", "cellular_location": "", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [ "A0AAF6DLT4-1", "A0AAA9TT54-1" ], "evidence": [ { "id": "18021", "database": "Rhea", "url": "https://www.rhea-db.org/rhea/18021" } ] }, { "id": "18913", "name": "", "equation": "a neolactoside nLc4Cer(d18:1(4E)) + CMP-N-acetyl-beta-neuraminate = a neolactoside IV(3)-alpha-NeuAc-nLc4Cer(d18:1(4E)) + CMP + H(+)", "summary": "", "cellular_location": "", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [ "Q6H8M7-1", "A0AAA9TT54-1" ], "evidence": [ { "id": "18913", "database": "Rhea", "url": "https://www.rhea-db.org/rhea/18913" } ] }, { "id": "21616", "name": "", "equation": "a beta-D-galactosyl-(1->3)-N-acetyl-alpha-D-galactosaminyl derivative + CMP-N-acetyl-beta-neuraminate = an N-acetyl-alpha-neuraminyl-(2->3)-beta-D-galactosyl-(1->3)-N-acetyl-alpha-D-galactosaminyl derivative + CMP + H(+)", "summary": "", "cellular_location": "", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [ "A0AAF6DLT4-1", "A0AAA9TT54-1" ], "evidence": [ { "id": "21616", "database": "Rhea", "url": "https://www.rhea-db.org/rhea/21616" } ] }, { "id": "47560", "name": "", "equation": "a ganglioside GA1 (d18:1(4E)) + CMP-N-acetyl-beta-neuraminate = a ganglioside GM1b (d18:1(4E)) + CMP + H(+)", "summary": "", "cellular_location": "", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [ "A0AAF6DLT4-1", "A0AAA9TT54-1" ], "evidence": [ { "id": "47560", "database": "Rhea", "url": "https://www.rhea-db.org/rhea/47560" } ] }, { "id": "47588", "name": "", "equation": "a ganglioside GT1c (d18:1(4E)) + CMP-N-acetyl-beta-neuraminate = a ganglioside GQ1c (d18:1(4E)) + CMP + H(+)", "summary": "", "cellular_location": "", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [ "A0AAA9TT54-1" ], "evidence": [ { "id": "47588", "database": "Rhea", "url": "https://www.rhea-db.org/rhea/47588" } ] }, { "id": "52316", "name": "", "equation": "a beta-D-galactosyl-(1->4)-N-acetyl-beta-D-glucosaminyl derivative + CMP-N-acetyl-beta-neuraminate = an N-acetyl-alpha-neuraminyl-(2->3)-beta-D-galactosyl-(1->4)-N-acetyl-beta-D-glucosaminyl derivative + CMP + H(+)", "summary": "", "cellular_location": "", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [ "Q6H8M7-1", "A0AAA9TT54-1", "F1MZD3-1" ], "evidence": [ { "id": "52316", "database": "Rhea", "url": "https://www.rhea-db.org/rhea/52316" } ] }, { "id": "52380", "name": "", "equation": "a beta-D-galactosyl-(1->3)-N-acetyl-beta-D-galactosaminyl derivative + CMP-N-acetyl-beta-neuraminate = an N-acetyl-alpha-neuraminyl-(2->3)-beta-D-galactosyl-(1->3)-N-acetyl-beta-D-galactosaminyl derivative + CMP + H(+)", "summary": "", "cellular_location": "", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [ "A0AAA9TT54-1" ], "evidence": [ { "id": "52380", "database": "Rhea", "url": "https://www.rhea-db.org/rhea/52380" } ] }, { "id": "65432", "name": "", "equation": "a neolactoside nLc4Cer + CMP-N-acetyl-beta-neuraminate = a neolactoside IV(3)-alpha-NeuAc-nLc4Cer + CMP + H(+)", "summary": "", "cellular_location": "", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [ "A0AAA9TT54-1" ], "evidence": [ { "id": "65432", "database": "Rhea", "url": "https://www.rhea-db.org/rhea/65432" } ] } ], "reaction_participants": [], "reaction_enzymes": [ { "uniprot_ac": "A0AAA9TT54", "gene_name": "ST3GAL4", "activity": [ { "ec_number": "2.4.3.2", "activity": "a ganglioside GM1 (d18:1(4E)) + CMP-N-acetyl-beta-neuraminate = a ganglioside GD1a (d18:1(4E)) + CMP + H(+).", "evidence": [ { "id": "A0AAA9TT54", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TT54" } ] }, { "ec_number": "2.4.3.4", "activity": "a beta-D-galactosyl-(1->3)-N-acetyl-alpha-D-galactosaminyl derivative + CMP-N-acetyl-beta-neuraminate = an N-acetyl-alpha-neuraminyl-(2->3)-beta-D-galactosyl-(1->3)-N-acetyl-alpha-D-galactosaminyl derivative + CMP + H(+).", "evidence": [ { "id": "A0AAA9TT54", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TT54" } ] }, { "ec_number": "2.4.3.6", "activity": "a beta-D-galactosyl-(1->4)-N-acetyl-beta-D-glucosaminyl derivative + CMP-N-acetyl-beta-neuraminate = an N-acetyl-alpha-neuraminyl-(2->3)-beta-D-galactosyl-(1->4)-N-acetyl-beta-D-glucosaminyl derivative + CMP + H(+).", "evidence": [ { "id": "A0AAA9TT54", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TT54" } ] }, { "ec_number": "2.4.3.2", "activity": "", "evidence": [ { "id": "A0AAA9TT54", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TT54" } ] }, { "ec_number": "2.4.3.6", "activity": "", "evidence": [ { "id": "A0AAA9TT54", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TT54" } ] }, { "ec_number": "2.4.3.4", "activity": "", "evidence": [ { "id": "A0AAA9TT54", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TT54" } ] } ] }, { "uniprot_ac": "A0AAF6DLT4", "gene_name": "ST3GAL1", "activity": [ { "ec_number": "2.4.3.2", "activity": "a ganglioside GM1 (d18:1(4E)) + CMP-N-acetyl-beta-neuraminate = a ganglioside GD1a (d18:1(4E)) + CMP + H(+).", "evidence": [ { "id": "A0AAF6DLT4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAF6DLT4" } ] }, { "ec_number": "2.4.3.4", "activity": "a beta-D-galactosyl-(1->3)-N-acetyl-alpha-D-galactosaminyl derivative + CMP-N-acetyl-beta-neuraminate = an N-acetyl-alpha-neuraminyl-(2->3)-beta-D-galactosyl-(1->3)-N-acetyl-alpha-D-galactosaminyl derivative + CMP + H(+).", "evidence": [ { "id": "A0AAF6DLT4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAF6DLT4" } ] }, { "ec_number": "2.4.3.2", "activity": "", "evidence": [ { "id": "A0AAF6DLT4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAF6DLT4" } ] }, { "ec_number": "2.4.3.4", "activity": "", "evidence": [ { "id": "A0AAF6DLT4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAF6DLT4" } ] } ] }, { "uniprot_ac": "F1MZD3", "gene_name": "ST3GAL3", "activity": [ { "ec_number": "2.4.3.6", "activity": "a beta-D-galactosyl-(1->4)-N-acetyl-beta-D-glucosaminyl derivative + CMP-N-acetyl-beta-neuraminate = an N-acetyl-alpha-neuraminyl-(2->3)-beta-D-galactosyl-(1->4)-N-acetyl-beta-D-glucosaminyl derivative + CMP + H(+).", "evidence": [ { "id": "F1MZD3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MZD3" } ] }, { "ec_number": "2.4.3.6", "activity": "", "evidence": [ { "id": "F1MZD3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MZD3" } ] } ] }, { "uniprot_ac": "Q6H8M7", "gene_name": "ST3GAL6", "activity": [ { "ec_number": "2.4.3.6", "activity": "a beta-D-galactosyl-(1->4)-N-acetyl-beta-D-glucosaminyl derivative + CMP-N-acetyl-beta-neuraminate = an N-acetyl-alpha-neuraminyl-(2->3)-beta-D-galactosyl-(1->4)-N-acetyl-beta-D-glucosaminyl derivative + CMP + H(+).", "evidence": [ { "id": "Q6H8M7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q6H8M7" } ] }, { "ec_number": "2.4.3.6", "activity": "", "evidence": [ { "id": "Q6H8M7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q6H8M7" } ] } ] } ], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [], "binding_sites": [], "synthesized_glycans": [ { "glytoucan_ac": "G00201AB", "type": "N-linked", "subtype": "Tetraantennary" }, { "glytoucan_ac": "G00231WL", "type": "N-linked", "subtype": "Tetraantennary" }, { "glytoucan_ac": "G00241VQ", "type": "O-linked", "subtype": "Core 2" }, { "glytoucan_ac": "G00320ZP", "type": "N-linked", "subtype": "Complex" }, { "glytoucan_ac": "G00368HM", "type": "N-linked", "subtype": "Triantennary" }, { "glytoucan_ac": "G00420CS", "type": "N-linked", "subtype": "Triantennary" }, { "glytoucan_ac": "G00468NI", "type": "O-linked", "subtype": "Core 2" }, { "glytoucan_ac": "G00531ZU", "type": "N-linked", "subtype": "Complex" }, { "glytoucan_ac": "G00646SN", "type": "N-linked", "subtype": "Triantennary" }, { "glytoucan_ac": "G00662IB", "type": "N-linked", "subtype": 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"type": "N-linked", "subtype": "Tetraantennary" }, { "glytoucan_ac": "G16759KR", "type": "N-linked", "subtype": "Complex" }, { "glytoucan_ac": "G16774YZ", "type": "N-linked", "subtype": "Tetraantennary" }, { "glytoucan_ac": "G16782SL", "type": "N-linked", "subtype": "Tetraantennary" }, { "glytoucan_ac": "G16827VK", "type": "N-linked", "subtype": "Triantennary" }, { "glytoucan_ac": "G16873YG", "type": "N-linked", "subtype": "Tetraantennary" }, { "glytoucan_ac": "G16986CA", "type": "N-linked", "subtype": "Triantennary" }, { "glytoucan_ac": "G17029BL", "type": "N-linked", "subtype": "Tetraantennary" }, { "glytoucan_ac": "G17041TR", "type": "N-linked", "subtype": "Tetraantennary" }, { "glytoucan_ac": "G17044PM", "type": "N-linked", "subtype": "Complex" }, { "glytoucan_ac": "G17118PL", "type": "N-linked", "subtype": "Complex" }, { "glytoucan_ac": "G17153CQ", "type": "N-linked", "subtype": "Triantennary" }, { "glytoucan_ac": "G17155VX", "type": "N-linked", "subtype": "Tetraantennary" }, { 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"G24293BT", "type": "O-linked", "subtype": "Core 2" }, { "glytoucan_ac": "G24336IA", "type": "N-linked", "subtype": "Triantennary" }, { "glytoucan_ac": "G24413UY", "type": "N-linked", "subtype": "Complex" }, { "glytoucan_ac": "G24475OY", "type": "O-linked", "subtype": "Core 2" }, { "glytoucan_ac": "G24517QL", "type": "N-linked", "subtype": "Other" }, { "glytoucan_ac": "G24546DC", "type": "N-linked", "subtype": "Triantennary" }, { "glytoucan_ac": "G24655MP", "type": "N-linked", "subtype": "Triantennary" }, { "glytoucan_ac": "G24705DL", "type": "N-linked", "subtype": "Triantennary" }, { "glytoucan_ac": "G24766QM", "type": "N-linked", "subtype": "Triantennary" }, { "glytoucan_ac": "G24798BT", "type": "O-linked", "subtype": "Core 4" }, { "glytoucan_ac": "G24816DA", "type": "N-linked", "subtype": "Tetraantennary" }, { "glytoucan_ac": "G24856YP", "type": "O-linked", "subtype": "Core 2" }, { "glytoucan_ac": "G24875YE", "type": "N-linked", "subtype": "Tetraantennary" }, { "glytoucan_ac": "G24920KE", "type": "N-linked", "subtype": "Triantennary" }, { "glytoucan_ac": "G24936MG", "type": "N-linked", "subtype": "Triantennary" }, { "glytoucan_ac": "G24970UY", "type": "N-linked", "subtype": "Core-fucosylated" }, { "glytoucan_ac": "G25019NQ", "type": "N-linked", "subtype": "Core-fucosylated" }, { "glytoucan_ac": "G25104PV", "type": "N-linked", "subtype": "Triantennary" }, { "glytoucan_ac": "G25127JU", "type": "O-linked", "subtype": "Core 2" }, { "glytoucan_ac": "G25173WC", "type": "N-linked", "subtype": "Tetraantennary" }, { "glytoucan_ac": "G25224QY", "type": "N-linked", "subtype": "Triantennary" }, { "glytoucan_ac": "G25297CU", "type": "N-linked", "subtype": "Tetraantennary" }, { "glytoucan_ac": "G25322NY", "type": "Other", "subtype": "Other" }, { "glytoucan_ac": "G25322UQ", "type": "N-linked", "subtype": "Tetraantennary" }, { "glytoucan_ac": "G25392ZR", "type": "N-linked", "subtype": "Tetraantennary" }, { "glytoucan_ac": "G25416CE", "type": "O-linked", "subtype": "Core 2" 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"Triantennary" }, { "glytoucan_ac": "G25977RW", "type": "O-linked", "subtype": "Core 2" }, { "glytoucan_ac": "G26068PU", "type": "N-linked", "subtype": "Tetraantennary" }, { "glytoucan_ac": "G26070CR", "type": "N-linked", "subtype": "Complex" }, { "glytoucan_ac": "G26099QT", "type": "O-linked", "subtype": "Core 4" }, { "glytoucan_ac": "G26137IM", "type": "N-linked", "subtype": "Tetraantennary" }, { "glytoucan_ac": "G26153IK", "type": "N-linked", "subtype": "Triantennary" }, { "glytoucan_ac": "G26179TW", "type": "N-linked", "subtype": "Core-fucosylated" }, { "glytoucan_ac": "G26264SQ", "type": "N-linked", "subtype": "Core-fucosylated" }, { "glytoucan_ac": "G26347KH", "type": "N-linked", "subtype": "Triantennary" }, { "glytoucan_ac": "G26357WC", "type": "N-linked", "subtype": "Complex" }, { "glytoucan_ac": "G26501HM", "type": "N-linked", "subtype": "Triantennary" }, { "glytoucan_ac": "G26520QU", "type": "N-linked", "subtype": "Triantennary" }, { "glytoucan_ac": "G26537DD", "type": "N-linked", "subtype": "Triantennary" }, { "glytoucan_ac": "G26566WH", "type": "N-linked", "subtype": "Hybrid" }, { "glytoucan_ac": "G26596ON", "type": "O-linked", "subtype": "Core 4" }, { "glytoucan_ac": "G26714JN", "type": "N-linked", "subtype": "Triantennary" }, { "glytoucan_ac": "G26739XH", "type": "N-linked", "subtype": "Tetraantennary" }, { "glytoucan_ac": "G26740EB", "type": "N-linked", "subtype": "Core-fucosylated" }, { "glytoucan_ac": "G26762AY", "type": "N-linked", "subtype": "Complex" }, { "glytoucan_ac": "G26935KA", "type": "N-linked", "subtype": "Tetraantennary" }, { "glytoucan_ac": "G27011YI", "type": "N-linked", "subtype": "Hybrid" }, { "glytoucan_ac": "G27067YD", "type": "N-linked", "subtype": "Triantennary" }, { "glytoucan_ac": "G27071PO", "type": "O-linked", "subtype": "Core 2" }, { "glytoucan_ac": "G27149SR", "type": "N-linked", "subtype": "Triantennary" }, { "glytoucan_ac": "G27170BX", "type": "N-linked", "subtype": "Complex" }, { "glytoucan_ac": "G27262AE", "type": "N-linked", "subtype": "Core-fucosylated" }, { "glytoucan_ac": "G27273FD", "type": "N-linked", "subtype": "Tetraantennary" }, { "glytoucan_ac": "G27409LG", "type": "O-linked", "subtype": "Core 2" }, { "glytoucan_ac": "G27419MQ", "type": "N-linked", "subtype": "Core-fucosylated" }, { "glytoucan_ac": "G27427OE", "type": "N-linked", "subtype": "Triantennary" }, { "glytoucan_ac": "G27501HT", "type": "N-linked", "subtype": "Core-fucosylated" }, { "glytoucan_ac": "G27516AE", "type": "N-linked", "subtype": "Triantennary" }, { "glytoucan_ac": "G27571QK", "type": "N-linked", "subtype": "Hybrid" }, { "glytoucan_ac": "G27629LY", "type": "N-linked", "subtype": "Core-fucosylated" }, { "glytoucan_ac": "G27741SW", "type": "N-linked", "subtype": "Core-fucosylated" }, { "glytoucan_ac": "G27814XA", "type": "N-linked", "subtype": "Core-fucosylated" }, { "glytoucan_ac": "G27844UM", "type": "N-linked", "subtype": "Tetraantennary" }, { "glytoucan_ac": "G27888XB", "type": "O-linked", "subtype": "Core 4" }, { 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"N-linked", "subtype": "Complex" }, { "glytoucan_ac": "G28747XN", "type": "N-linked", "subtype": "Core-fucosylated" }, { "glytoucan_ac": "G28862MM", "type": "N-linked", "subtype": "Triantennary" }, { "glytoucan_ac": "G28877HV", "type": "O-linked", "subtype": "Core 2" }, { "glytoucan_ac": "G28882QV", "type": "N-linked", "subtype": "Core-fucosylated" }, { "glytoucan_ac": "G28885XK", "type": "Other", "subtype": "Other" }, { "glytoucan_ac": "G28954HQ", "type": "N-linked", "subtype": "Triantennary" }, { "glytoucan_ac": "G28957FB", "type": "N-linked", "subtype": "Tetraantennary" }, { "glytoucan_ac": "G29003YB", "type": "N-linked", "subtype": "Tetraantennary" }, { "glytoucan_ac": "G29011KL", "type": "N-linked", "subtype": "Core-fucosylated" }, { "glytoucan_ac": "G29014XV", "type": "O-linked", "subtype": "Core 2" }, { "glytoucan_ac": "G29017AP", "type": "N-linked", "subtype": "Complex" }, { "glytoucan_ac": "G29130SY", "type": "N-linked", "subtype": "Complex" }, { "glytoucan_ac": "G29184OZ", "type": "N-linked", "subtype": "Complex" }, { "glytoucan_ac": "G29248WR", "type": "N-linked", "subtype": "Complex" }, { "glytoucan_ac": "G29276DW", "type": "N-linked", "subtype": "Core-fucosylated" }, { "glytoucan_ac": "G29277BJ", "type": "N-linked", "subtype": "Tetraantennary" }, { "glytoucan_ac": "G29443MC", "type": "N-linked", "subtype": "Triantennary" }, { "glytoucan_ac": "G29524AT", "type": "O-linked", "subtype": "Core 4" }, { "glytoucan_ac": "G29630IH", "type": "N-linked", "subtype": "Triantennary" }, { "glytoucan_ac": "G29633ZY", "type": "N-linked", "subtype": "Complex" }, { "glytoucan_ac": "G29764SO", "type": "N-linked", "subtype": "Triantennary" }, { "glytoucan_ac": "G29818DV", "type": "N-linked", "subtype": "Tetraantennary" }, { "glytoucan_ac": "G29857PJ", "type": "N-linked", "subtype": "Triantennary" }, { "glytoucan_ac": "G30035MO", "type": "N-linked", "subtype": "Complex" }, { "glytoucan_ac": "G30055GV", "type": "N-linked", "subtype": "Tetraantennary" }, { "glytoucan_ac": "G30062BR", "type": "N-linked", "subtype": "Tetraantennary" }, { "glytoucan_ac": "G30067CL", "type": "N-linked", "subtype": "Tetraantennary" }, { "glytoucan_ac": "G30171GE", "type": "N-linked", "subtype": "Triantennary" }, { "glytoucan_ac": "G30229IT", "type": "N-linked", "subtype": "Tetraantennary" }, { "glytoucan_ac": "G30296PK", "type": "O-linked", "subtype": "Core 4" }, { "glytoucan_ac": "G30371AX", "type": "N-linked", "subtype": "Triantennary" }, { "glytoucan_ac": "G30392XP", "type": "O-linked", "subtype": "Core 2" }, { "glytoucan_ac": "G30431XW", "type": "O-linked", "subtype": "Core 4" }, { "glytoucan_ac": "G30437YI", "type": "N-linked", "subtype": "Tetraantennary" }, { "glytoucan_ac": "G30447NS", "type": "N-linked", "subtype": "Tetraantennary" }, { "glytoucan_ac": "G30460NZ", "type": "N-linked", "subtype": "Core-fucosylated" }, { "glytoucan_ac": "G30723RE", "type": "N-linked", "subtype": "Core-fucosylated" }, { "glytoucan_ac": "G30736BQ", "type": "O-linked", "subtype": "Core 2" 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"N-linked", "subtype": "Triantennary" }, { "glytoucan_ac": "G31606TH", "type": "N-linked", "subtype": "Tetraantennary" }, { "glytoucan_ac": "G31662BR", "type": "N-linked", "subtype": "Triantennary" }, { "glytoucan_ac": "G31668AP", "type": "N-linked", "subtype": "Complex" }, { "glytoucan_ac": "G31692TJ", "type": "N-linked", "subtype": "Complex" }, { "glytoucan_ac": "G31721AZ", "type": "N-linked", "subtype": "Tetraantennary" }, { "glytoucan_ac": "G31828QS", "type": "N-linked", "subtype": "Complex" }, { "glytoucan_ac": "G31873MP", "type": "N-linked", "subtype": "Hybrid" }, { "glytoucan_ac": "G31948FR", "type": "O-linked", "subtype": "Core 3" }, { "glytoucan_ac": "G31984FM", "type": "N-linked", "subtype": "Triantennary" }, { "glytoucan_ac": "G32079YD", "type": "N-linked", "subtype": "Triantennary" }, { "glytoucan_ac": "G32114CQ", "type": "N-linked", "subtype": "Complex" }, { "glytoucan_ac": "G32216KM", "type": "N-linked", "subtype": "Complex" }, { "glytoucan_ac": "G32287FD", "type": "N-linked", "subtype": "Tetraantennary" }, { "glytoucan_ac": "G32289FM", "type": "O-linked", "subtype": "Core 2" }, { "glytoucan_ac": "G32364DF", "type": "N-linked", "subtype": "Triantennary" }, { "glytoucan_ac": "G32377GZ", "type": "N-linked", "subtype": "Tetraantennary" }, { "glytoucan_ac": "G32395UL", "type": "N-linked", "subtype": "Triantennary" }, { "glytoucan_ac": "G32418LI", "type": "N-linked", "subtype": "Tetraantennary" }, { "glytoucan_ac": "G32452EX", "type": "N-linked", "subtype": "Core-fucosylated" }, { "glytoucan_ac": "G32461GF", "type": "N-linked", "subtype": "Tetraantennary" }, { "glytoucan_ac": "G32510IZ", "type": "N-linked", "subtype": "Triantennary" }, { "glytoucan_ac": "G32556JI", "type": "O-linked", "subtype": "Core 4" }, { "glytoucan_ac": "G32590UP", "type": "O-linked", "subtype": "Core 2" }, { "glytoucan_ac": "G32592IB", "type": "N-linked", "subtype": "Triantennary" }, { "glytoucan_ac": "G32659RY", "type": "N-linked", "subtype": "Core-fucosylated" }, { 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"N-linked", "subtype": "Triantennary" }, { "glytoucan_ac": "G34082PC", "type": "N-linked", "subtype": "Triantennary" }, { "glytoucan_ac": "G34291TF", "type": "N-linked", "subtype": "Tetraantennary" }, { "glytoucan_ac": "G34330HT", "type": "N-linked", "subtype": "Complex" }, { "glytoucan_ac": "G34343FT", "type": "N-linked", "subtype": "Triantennary" }, { "glytoucan_ac": "G34392KZ", "type": "N-linked", "subtype": "Other" }, { "glytoucan_ac": "G34457IL", "type": "N-linked", "subtype": "Complex" }, { "glytoucan_ac": "G34508UC", "type": "N-linked", "subtype": "Core-fucosylated" }, { "glytoucan_ac": "G34561BL", "type": "N-linked", "subtype": "Triantennary" }, { "glytoucan_ac": "G34611ON", "type": "N-linked", "subtype": "Triantennary" }, { "glytoucan_ac": "G34631OW", "type": "N-linked", "subtype": "Complex" }, { "glytoucan_ac": "G34725PD", "type": "N-linked", "subtype": "Core-fucosylated" }, { "glytoucan_ac": "G34731QC", "type": "N-linked", "subtype": "Triantennary" }, { "glytoucan_ac": "G34748WY", "type": "N-linked", "subtype": "Triantennary" }, { "glytoucan_ac": "G34784SE", "type": "N-linked", "subtype": "Core-fucosylated" }, { "glytoucan_ac": "G34819LS", "type": "N-linked", "subtype": "Tetraantennary" }, { "glytoucan_ac": "G34851VW", "type": "N-linked", "subtype": "Core-fucosylated" }, { "glytoucan_ac": "G34859KW", "type": "N-linked", "subtype": "Complex" }, { "glytoucan_ac": "G34863TS", "type": "O-linked", "subtype": "Core 4" }, { "glytoucan_ac": "G34931KK", "type": "N-linked", "subtype": "Triantennary" }, { "glytoucan_ac": "G34972BB", "type": "N-linked", "subtype": "Triantennary" }, { "glytoucan_ac": "G35105ZB", "type": "N-linked", "subtype": "Complex" }, { "glytoucan_ac": "G35199BM", "type": "O-linked", "subtype": "Core 2" }, { "glytoucan_ac": "G35243PQ", "type": "O-linked", "subtype": "Core 2" }, { "glytoucan_ac": "G35313CG", "type": "N-linked", "subtype": "Triantennary" }, { "glytoucan_ac": "G35347OW", "type": "N-linked", "subtype": "Tetraantennary" }, { 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"Complex" }, { "glytoucan_ac": "G35945JK", "type": "O-linked", "subtype": "Core 4" }, { "glytoucan_ac": "G36003IA", "type": "N-linked", "subtype": "Core-fucosylated" }, { "glytoucan_ac": "G36020VB", "type": "N-linked", "subtype": "Complex" }, { "glytoucan_ac": "G36042WR", "type": "N-linked", "subtype": "Tetraantennary" }, { "glytoucan_ac": "G36070GZ", "type": "N-linked", "subtype": "Core-fucosylated" }, { "glytoucan_ac": "G36138ZV", "type": "O-linked", "subtype": "Core 2" }, { "glytoucan_ac": "G36152VT", "type": "N-linked", "subtype": "Core-fucosylated" }, { "glytoucan_ac": "G36171JA", "type": "N-linked", "subtype": "Core-fucosylated" }, { "glytoucan_ac": "G36191EH", "type": "O-linked", "subtype": "Core 3" }, { "glytoucan_ac": "G36194BW", "type": "N-linked", "subtype": "Core-fucosylated" }, { "glytoucan_ac": "G36200ZL", "type": "N-linked", "subtype": "Triantennary" }, { "glytoucan_ac": "G36223VW", "type": "N-linked", "subtype": "Triantennary" }, { "glytoucan_ac": "G36268TW", "type": "N-linked", "subtype": "Complex" }, { "glytoucan_ac": "G36287XJ", "type": "N-linked", "subtype": "Complex" }, { "glytoucan_ac": "G36297RV", "type": "N-linked", "subtype": "Triantennary" }, { "glytoucan_ac": "G36303CE", "type": "N-linked", "subtype": "Tetraantennary" }, { "glytoucan_ac": "G36311ZH", "type": "N-linked", "subtype": "Triantennary" }, { "glytoucan_ac": "G36324QX", "type": "N-linked", "subtype": "Complex" }, { "glytoucan_ac": "G36341AR", "type": "N-linked", "subtype": "Triantennary" }, { "glytoucan_ac": "G36378FM", "type": "N-linked", "subtype": "Triantennary" }, { "glytoucan_ac": "G36443XA", "type": "Other", "subtype": "Other" }, { "glytoucan_ac": "G36484FP", "type": "N-linked", "subtype": "Triantennary" }, { "glytoucan_ac": "G36501YX", "type": "N-linked", "subtype": "Hybrid" }, { "glytoucan_ac": "G36519NW", "type": "N-linked", "subtype": "Triantennary" }, { "glytoucan_ac": "G36588OE", "type": "N-linked", "subtype": "Core-fucosylated" }, { "glytoucan_ac": "G36626AJ", "type": "N-linked", "subtype": "Tetraantennary" }, { "glytoucan_ac": "G36701GV", "type": "N-linked", "subtype": "Core-fucosylated" }, { "glytoucan_ac": "G36766ZC", "type": "N-linked", "subtype": "Complex" }, { "glytoucan_ac": "G36806TM", "type": "N-linked", "subtype": "Triantennary" }, { "glytoucan_ac": "G36807HJ", "type": "N-linked", "subtype": "Hybrid" }, { "glytoucan_ac": "G36847DS", "type": "N-linked", "subtype": "Triantennary" }, { "glytoucan_ac": "G36983SB", "type": "O-linked", "subtype": "Core 2" }, { "glytoucan_ac": "G37022BP", "type": "N-linked", "subtype": "Core-fucosylated" }, { "glytoucan_ac": "G37166HP", "type": "N-linked", "subtype": "Hybrid" }, { "glytoucan_ac": "G37239FO", "type": "O-linked", "subtype": "Core 2" }, { "glytoucan_ac": "G37271FP", "type": "N-linked", "subtype": "Triantennary" }, { "glytoucan_ac": "G37304XT", "type": "N-linked", "subtype": "Triantennary" }, { "glytoucan_ac": "G37306TB", "type": "N-linked", "subtype": "Triantennary" }, { "glytoucan_ac": "G37330EE", "type": "N-linked", "subtype": "Triantennary" }, { "glytoucan_ac": "G37354FL", "type": "O-linked", "subtype": "Core 2" }, { "glytoucan_ac": "G37487GB", "type": "N-linked", "subtype": "Triantennary" }, { "glytoucan_ac": "G37488LQ", "type": "N-linked", "subtype": "Tetraantennary" }, { "glytoucan_ac": "G37492BZ", "type": "N-linked", "subtype": "Triantennary" }, { "glytoucan_ac": "G37626KE", "type": "N-linked", "subtype": "Triantennary" }, { "glytoucan_ac": "G37669IH", "type": "N-linked", "subtype": "Tetraantennary" }, { "glytoucan_ac": "G37718JO", "type": "N-linked", "subtype": "Triantennary" }, { "glytoucan_ac": "G37990ZT", "type": "N-linked", "subtype": "Tetraantennary" }, { "glytoucan_ac": "G38022PE", "type": "N-linked", "subtype": "Triantennary" }, { "glytoucan_ac": "G38027UF", "type": "O-linked", "subtype": "Core 2" }, { "glytoucan_ac": "G38117WE", "type": "N-linked", "subtype": "Complex" }, { "glytoucan_ac": "G38121TQ", "type": "N-linked", "subtype": "Core-fucosylated" 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"Core 2" }, { "glytoucan_ac": "G38613YU", "type": "N-linked", "subtype": "Tetraantennary" }, { "glytoucan_ac": "G38625SV", "type": "N-linked", "subtype": "Complex" }, { "glytoucan_ac": "G38637SA", "type": "N-linked", "subtype": "Triantennary" }, { "glytoucan_ac": "G38658JL", "type": "N-linked", "subtype": "Triantennary" }, { "glytoucan_ac": "G38887NC", "type": "N-linked", "subtype": "Triantennary" }, { "glytoucan_ac": "G38901GU", "type": "N-linked", "subtype": "Triantennary" }, { "glytoucan_ac": "G38922KN", "type": "N-linked", "subtype": "Tetraantennary" }, { "glytoucan_ac": "G38948TJ", "type": "N-linked", "subtype": "Triantennary" }, { "glytoucan_ac": "G38955TH", "type": "N-linked", "subtype": "Hybrid" }, { "glytoucan_ac": "G38979WI", "type": "O-linked", "subtype": "Core 2" }, { "glytoucan_ac": "G39027MU", "type": "N-linked", "subtype": "Complex" }, { "glytoucan_ac": "G39035OI", "type": "N-linked", "subtype": "Triantennary" }, { "glytoucan_ac": "G39132UF", "type": "N-linked", "subtype": "Tetraantennary" }, { "glytoucan_ac": "G39136RY", "type": "N-linked", "subtype": "Complex" }, { "glytoucan_ac": "G39183DW", "type": "N-linked", "subtype": "Tetraantennary" }, { "glytoucan_ac": "G39189IR", "type": "O-linked", "subtype": "Core 3" }, { "glytoucan_ac": "G39292VX", "type": "N-linked", "subtype": "Triantennary" }, { "glytoucan_ac": "G39299DH", "type": "N-linked", "subtype": "Triantennary" }, { "glytoucan_ac": "G39302PS", "type": "N-linked", "subtype": "Complex" }, { "glytoucan_ac": "G39321UZ", "type": "O-linked", "subtype": "Core 4" }, { "glytoucan_ac": "G39342SG", "type": "N-linked", "subtype": "Core-fucosylated" }, { "glytoucan_ac": "G39377DE", "type": "N-linked", "subtype": "Core-fucosylated" }, { "glytoucan_ac": "G39439UR", "type": "N-linked", "subtype": "Core-fucosylated" }, { "glytoucan_ac": "G39534CW", "type": "N-linked", "subtype": "Hybrid" }, { "glytoucan_ac": "G39540XG", "type": "N-linked", "subtype": "Complex" }, { "glytoucan_ac": "G39567LQ", "type": "N-linked", "subtype": "Triantennary" }, { "glytoucan_ac": "G39600NF", "type": "N-linked", "subtype": "Tetraantennary" }, { "glytoucan_ac": "G39624YQ", "type": "O-linked", "subtype": "Core 4" }, { "glytoucan_ac": "G39661KT", "type": "N-linked", "subtype": "Triantennary" }, { "glytoucan_ac": "G39676NA", "type": "O-linked", "subtype": "Core 2" }, { "glytoucan_ac": "G39722LF", "type": "N-linked", "subtype": "Core-fucosylated" }, { "glytoucan_ac": "G39756ZC", "type": "N-linked", "subtype": "Core-fucosylated" }, { "glytoucan_ac": "G39760IQ", "type": "N-linked", "subtype": "Core-fucosylated" }, { "glytoucan_ac": "G39761CO", "type": "N-linked", "subtype": "Hybrid" }, { "glytoucan_ac": "G39824OQ", "type": "N-linked", "subtype": "Complex" }, { "glytoucan_ac": "G39977UQ", "type": "N-linked", "subtype": "Triantennary" }, { "glytoucan_ac": "G40027VO", "type": "N-linked", "subtype": "Tetraantennary" }, { "glytoucan_ac": "G40064GR", "type": "N-linked", "subtype": "Complex" }, { "glytoucan_ac": "G40194MN", "type": "N-linked", "subtype": "Tetraantennary" }, { "glytoucan_ac": "G40212MM", "type": "N-linked", "subtype": "Core-fucosylated" }, { "glytoucan_ac": "G40219EV", "type": "N-linked", "subtype": "Tetraantennary" }, { "glytoucan_ac": "G40236GK", "type": "N-linked", "subtype": "Triantennary" }, { "glytoucan_ac": "G40289VL", "type": "O-linked", "subtype": "Core 2" }, { "glytoucan_ac": "G40341NV", "type": "N-linked", "subtype": "Other" }, { "glytoucan_ac": "G40343KH", "type": "N-linked", "subtype": "Tetraantennary" }, { "glytoucan_ac": "G40411HQ", "type": "N-linked", "subtype": "Triantennary" }, { "glytoucan_ac": "G40445LE", "type": "Other", "subtype": "Other" }, { "glytoucan_ac": "G40452FK", "type": "N-linked", "subtype": "Triantennary" }, { "glytoucan_ac": "G40463TJ", "type": "N-linked", "subtype": "Core-fucosylated" }, { "glytoucan_ac": "G40472QE", "type": "N-linked", "subtype": "Hybrid" }, { "glytoucan_ac": "G40513EI", "type": "N-linked", "subtype": "Tetraantennary" }, { 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"N-linked", "subtype": "Core-fucosylated" }, { "glytoucan_ac": "G42060JY", "type": "N-linked", "subtype": "Triantennary" }, { "glytoucan_ac": "G42089IU", "type": "O-linked", "subtype": "Core 2" }, { "glytoucan_ac": "G42123IU", "type": "N-linked", "subtype": "Tetraantennary" }, { "glytoucan_ac": "G42133YG", "type": "N-linked", "subtype": "Core-fucosylated" }, { "glytoucan_ac": "G42139GR", "type": "N-linked", "subtype": "Tetraantennary" }, { "glytoucan_ac": "G42305NI", "type": "N-linked", "subtype": "Triantennary" }, { "glytoucan_ac": "G42365AT", "type": "N-linked", "subtype": "Triantennary" }, { "glytoucan_ac": "G42380GI", "type": "N-linked", "subtype": "Tetraantennary" }, { "glytoucan_ac": "G42393CS", "type": "O-linked", "subtype": "Core 2" }, { "glytoucan_ac": "G42482KG", "type": "N-linked", "subtype": "Core-fucosylated" }, { "glytoucan_ac": "G42531AE", "type": "O-linked", "subtype": "Core 3" }, { "glytoucan_ac": "G42600SB", "type": "N-linked", "subtype": "Triantennary" }, { 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"Triantennary" }, { "glytoucan_ac": "G43088GK", "type": "N-linked", "subtype": "Tetraantennary" }, { "glytoucan_ac": "G43095XB", "type": "N-linked", "subtype": "Triantennary" }, { "glytoucan_ac": "G43164CL", "type": "N-linked", "subtype": "Triantennary" }, { "glytoucan_ac": "G43167FQ", "type": "O-linked", "subtype": "Core 4" }, { "glytoucan_ac": "G43220WQ", "type": "O-linked", "subtype": "Core 2" }, { "glytoucan_ac": "G43242DB", "type": "N-linked", "subtype": "Triantennary" }, { "glytoucan_ac": "G43255OW", "type": "N-linked", "subtype": "Core-fucosylated" }, { "glytoucan_ac": "G43265YA", "type": "O-linked", "subtype": "Core 4" }, { "glytoucan_ac": "G43330ZT", "type": "N-linked", "subtype": "Core-fucosylated" }, { "glytoucan_ac": "G43346PX", "type": "N-linked", "subtype": "Core-fucosylated" }, { "glytoucan_ac": "G43346UV", "type": "N-linked", "subtype": "Triantennary" }, { "glytoucan_ac": "G43351VW", "type": "N-linked", "subtype": "Triantennary" }, { "glytoucan_ac": "G43374FV", "type": "N-linked", "subtype": "Core-fucosylated" }, { "glytoucan_ac": "G43502GT", "type": "N-linked", "subtype": "Core-fucosylated" }, { "glytoucan_ac": "G43507KQ", "type": "N-linked", "subtype": "Core-fucosylated" }, { "glytoucan_ac": "G43526DL", "type": "N-linked", "subtype": "Tetraantennary" }, { "glytoucan_ac": "G43556OK", "type": "N-linked", "subtype": "Tetraantennary" }, { "glytoucan_ac": "G43596KL", "type": "N-linked", "subtype": "Tetraantennary" }, { "glytoucan_ac": "G43645EE", "type": "N-linked", "subtype": "Triantennary" }, { "glytoucan_ac": "G43665PB", "type": "N-linked", "subtype": "Core-fucosylated" }, { "glytoucan_ac": "G43668RJ", "type": "O-linked", "subtype": "Core 2" }, { "glytoucan_ac": "G43680SH", "type": "N-linked", "subtype": "Triantennary" }, { "glytoucan_ac": "G43702IX", "type": "N-linked", "subtype": "Triantennary" }, { "glytoucan_ac": "G43749GH", "type": "N-linked", "subtype": "Core-fucosylated" }, { "glytoucan_ac": "G43832DJ", "type": "N-linked", "subtype": 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"N-linked", "subtype": "Triantennary" }, { "glytoucan_ac": "G45661AN", "type": "N-linked", "subtype": "Complex" }, { "glytoucan_ac": "G45707SN", "type": "O-linked", "subtype": "Core 2" }, { "glytoucan_ac": "G45712YX", "type": "N-linked", "subtype": "Triantennary" }, { "glytoucan_ac": "G45718WR", "type": "O-linked", "subtype": "Core 2" }, { "glytoucan_ac": "G45747TC", "type": "N-linked", "subtype": "Triantennary" }, { "glytoucan_ac": "G45756EL", "type": "O-linked", "subtype": "Core 2" }, { "glytoucan_ac": "G45776ET", "type": "N-linked", "subtype": "Tetraantennary" }, { "glytoucan_ac": "G46103YX", "type": "N-linked", "subtype": "Tetraantennary" }, { "glytoucan_ac": "G46108US", "type": "N-linked", "subtype": "Tetraantennary" }, { "glytoucan_ac": "G46141DD", "type": "N-linked", "subtype": "Triantennary" }, { "glytoucan_ac": "G46165ME", "type": "N-linked", "subtype": "Tetraantennary" }, { "glytoucan_ac": "G46171QF", "type": "N-linked", "subtype": "Triantennary" }, { "glytoucan_ac": 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"type": "N-linked", "subtype": "Triantennary" }, { "glytoucan_ac": "G50252SB", "type": "O-linked", "subtype": "Core 2" }, { "glytoucan_ac": "G50364FV", "type": "N-linked", "subtype": "Tetraantennary" }, { "glytoucan_ac": "G50387OH", "type": "N-linked", "subtype": "Complex" }, { "glytoucan_ac": "G50427EN", "type": "N-linked", "subtype": "Core-fucosylated" }, { "glytoucan_ac": "G50462VS", "type": "N-linked", "subtype": "Tetraantennary" }, { "glytoucan_ac": "G50489VC", "type": "N-linked", "subtype": "Tetraantennary" }, { "glytoucan_ac": "G50508SG", "type": "N-linked", "subtype": "Tetraantennary" }, { "glytoucan_ac": "G50518XT", "type": "N-linked", "subtype": "Core-fucosylated" }, { "glytoucan_ac": "G50525GP", "type": "N-linked", "subtype": "Complex" }, { "glytoucan_ac": "G50554LM", "type": "N-linked", "subtype": "Triantennary" }, { "glytoucan_ac": "G50584UT", "type": "N-linked", "subtype": "Triantennary" }, { "glytoucan_ac": "G50652EJ", "type": "O-linked", "subtype": "Core 2" }, { "glytoucan_ac": "G50660UT", "type": "N-linked", "subtype": "Tetraantennary" }, { "glytoucan_ac": "G50706US", "type": "N-linked", "subtype": "Complex" }, { "glytoucan_ac": "G50731QB", "type": "N-linked", "subtype": "Core-fucosylated" }, { "glytoucan_ac": "G50782LR", "type": "N-linked", "subtype": "Triantennary" }, { "glytoucan_ac": "G50802FP", "type": "O-linked", "subtype": "Core 6" }, { "glytoucan_ac": "G50808YS", "type": "O-linked", "subtype": "Core 2" }, { "glytoucan_ac": "G50821RC", "type": "N-linked", "subtype": "Triantennary" }, { "glytoucan_ac": "G50880EE", "type": "N-linked", "subtype": "Core-fucosylated" }, { "glytoucan_ac": "G50896EJ", "type": "O-linked", "subtype": "Core 2" }, { "glytoucan_ac": "G50915WK", "type": "N-linked", "subtype": "Core-fucosylated" }, { "glytoucan_ac": "G50937OW", "type": "O-linked", "subtype": "Core 2" }, { "glytoucan_ac": "G50997KD", "type": "N-linked", "subtype": "Tetraantennary" }, { "glytoucan_ac": "G51018GI", "type": "N-linked", "subtype": "Triantennary" }, { "glytoucan_ac": "G51066TO", "type": "N-linked", "subtype": "Core-fucosylated" }, { "glytoucan_ac": "G51074KT", "type": "N-linked", "subtype": "Complex" }, { "glytoucan_ac": "G51086FE", "type": "N-linked", "subtype": "Triantennary" }, { "glytoucan_ac": "G51098AA", "type": "N-linked", "subtype": "Triantennary" }, { "glytoucan_ac": "G51162XR", "type": "O-linked", "subtype": "Core 3" }, { "glytoucan_ac": "G51168MK", "type": "N-linked", "subtype": "Triantennary" }, { "glytoucan_ac": "G51229TU", "type": "N-linked", "subtype": "Core-fucosylated" }, { "glytoucan_ac": "G51324UL", "type": "N-linked", "subtype": "Triantennary" }, { "glytoucan_ac": "G51333KM", "type": "N-linked", "subtype": "Core-fucosylated" }, { "glytoucan_ac": "G51402XK", "type": "N-linked", "subtype": "Tetraantennary" }, { "glytoucan_ac": "G51411MW", "type": "N-linked", "subtype": "Complex" }, { "glytoucan_ac": "G51500KY", "type": "O-linked", "subtype": "Core 2" }, { "glytoucan_ac": "G51530ER", "type": "N-linked", "subtype": "Core-fucosylated" }, { "glytoucan_ac": "G51586EE", "type": "O-linked", "subtype": "Core 2" }, { "glytoucan_ac": "G51678TA", "type": "Other", "subtype": "Other" }, { "glytoucan_ac": "G51710QD", "type": "N-linked", "subtype": "Tetraantennary" }, { "glytoucan_ac": "G51768ZH", "type": "N-linked", "subtype": "Tetraantennary" }, { "glytoucan_ac": "G51793MY", "type": "N-linked", "subtype": "Complex" }, { "glytoucan_ac": "G51878LH", "type": "N-linked", "subtype": "Core-fucosylated" }, { "glytoucan_ac": "G51891DI", "type": "N-linked", "subtype": "Core-fucosylated" }, { "glytoucan_ac": "G51921XC", "type": "N-linked", "subtype": "Triantennary" }, { "glytoucan_ac": "G51929IB", "type": "N-linked", "subtype": "Core-fucosylated" }, { "glytoucan_ac": "G52021KR", "type": "N-linked", "subtype": "Core-fucosylated" }, { "glytoucan_ac": "G52120NK", "type": "O-linked", "subtype": "Core 2" }, { "glytoucan_ac": "G52210EC", "type": "N-linked", "subtype": "Tetraantennary" }, { "glytoucan_ac": "G52266YB", "type": "N-linked", "subtype": "Triantennary" }, { "glytoucan_ac": "G52345FK", "type": "N-linked", "subtype": "Triantennary" }, { "glytoucan_ac": "G52383QH", "type": "N-linked", "subtype": "Triantennary" }, { "glytoucan_ac": "G52441NC", "type": "N-linked", "subtype": "Core-fucosylated" }, { "glytoucan_ac": "G52483OL", "type": "N-linked", "subtype": "Triantennary" }, { "glytoucan_ac": "G52497YI", "type": "N-linked", "subtype": "Core-fucosylated" }, { "glytoucan_ac": "G52593LK", "type": "N-linked", "subtype": "Triantennary" }, { "glytoucan_ac": "G52621OJ", "type": "N-linked", "subtype": "Triantennary" }, { "glytoucan_ac": "G52645LW", "type": "N-linked", "subtype": "Triantennary" }, { "glytoucan_ac": "G52676LZ", "type": "N-linked", "subtype": "Core-fucosylated" }, { "glytoucan_ac": "G52701UC", "type": "N-linked", "subtype": "Core-fucosylated" }, { "glytoucan_ac": "G52790YS", "type": "N-linked", "subtype": "Triantennary" }, { "glytoucan_ac": "G52794ID", "type": "O-linked", "subtype": "Core 2" }, { "glytoucan_ac": "G52892AY", "type": "N-linked", "subtype": "Triantennary" }, { "glytoucan_ac": "G52971DE", "type": "N-linked", "subtype": "Complex" }, { "glytoucan_ac": "G53028BV", "type": "N-linked", "subtype": "Triantennary" }, { "glytoucan_ac": "G53064IK", "type": "Other", "subtype": "Other" }, { "glytoucan_ac": "G53173PI", "type": "N-linked", "subtype": "Hybrid" }, { "glytoucan_ac": "G53208AY", "type": "O-linked", "subtype": "Core 3" }, { "glytoucan_ac": "G53220ZS", "type": "O-linked", "subtype": "Core 2" }, { "glytoucan_ac": "G53234IR", "type": "N-linked", "subtype": "Tetraantennary" }, { "glytoucan_ac": "G53361RA", "type": "N-linked", "subtype": "Triantennary" }, { "glytoucan_ac": "G53396PX", "type": "N-linked", "subtype": "Triantennary" }, { "glytoucan_ac": "G53396TS", "type": "O-linked", "subtype": "Core 6" }, { "glytoucan_ac": "G53472RQ", "type": "O-linked", "subtype": "Core 2" }, { "glytoucan_ac": "G53504BR", "type": "N-linked", "subtype": "Tetraantennary" }, { "glytoucan_ac": "G53527TY", "type": "O-linked", "subtype": "Core 2" }, { "glytoucan_ac": "G53574BW", "type": "N-linked", "subtype": "Triantennary" }, { "glytoucan_ac": "G53723XK", "type": "N-linked", "subtype": "Triantennary" }, { "glytoucan_ac": "G53752TA", "type": "N-linked", "subtype": "Core-fucosylated" }, { "glytoucan_ac": "G53768QW", "type": "N-linked", "subtype": "Complex" }, { "glytoucan_ac": "G53778MF", "type": "O-linked", "subtype": "Core 2" }, { "glytoucan_ac": "G53795OV", "type": "N-linked", "subtype": "Complex" }, { "glytoucan_ac": "G53800IE", "type": "N-linked", "subtype": "Hybrid" }, { "glytoucan_ac": "G53800MQ", "type": "N-linked", "subtype": "Tetraantennary" }, { "glytoucan_ac": "G53809CJ", "type": "N-linked", "subtype": "Core-fucosylated" }, { "glytoucan_ac": "G53812BX", "type": "N-linked", "subtype": "Triantennary" }, { "glytoucan_ac": "G53818ZZ", "type": "N-linked", "subtype": "Triantennary" }, { "glytoucan_ac": "G53840IC", "type": "N-linked", "subtype": "Triantennary" }, { "glytoucan_ac": "G53856PB", "type": "O-linked", "subtype": "Core 2" }, { "glytoucan_ac": "G53869ZZ", "type": "O-linked", "subtype": "Core 3" }, { "glytoucan_ac": "G53923UR", "type": "N-linked", "subtype": "Core-fucosylated" }, { "glytoucan_ac": "G53944MR", "type": "N-linked", "subtype": "Core-fucosylated" }, { "glytoucan_ac": "G53962WT", "type": "N-linked", "subtype": "Hybrid" }, { "glytoucan_ac": "G53993HS", "type": "N-linked", "subtype": "Tetraantennary" }, { "glytoucan_ac": "G54010TZ", "type": "N-linked", "subtype": "Triantennary" }, { "glytoucan_ac": "G54018RP", "type": "N-linked", "subtype": "Tetraantennary" }, { "glytoucan_ac": "G54076UX", "type": "N-linked", "subtype": "Core-fucosylated" }, { "glytoucan_ac": "G54083SI", "type": "O-linked", "subtype": "Core 2" }, { "glytoucan_ac": "G54158IT", "type": "N-linked", "subtype": "Tetraantennary" }, { "glytoucan_ac": "G54162HE", "type": "N-linked", "subtype": "Tetraantennary" }, { "glytoucan_ac": "G54198RS", "type": "N-linked", "subtype": "Core-fucosylated" }, { "glytoucan_ac": "G54300AX", "type": "N-linked", "subtype": "Triantennary" }, { "glytoucan_ac": "G54317NJ", "type": "N-linked", "subtype": "Triantennary" }, { "glytoucan_ac": "G54338PJ", "type": "N-linked", "subtype": "Triantennary" }, { "glytoucan_ac": "G54380FJ", "type": "N-linked", "subtype": "Core-fucosylated" }, { "glytoucan_ac": "G54413TX", "type": "N-linked", "subtype": "Core-fucosylated" }, { "glytoucan_ac": "G54505OS", "type": "N-linked", "subtype": "Complex" }, { "glytoucan_ac": "G54507ZF", "type": "N-linked", "subtype": "Core-fucosylated" }, { "glytoucan_ac": "G54513OG", "type": "N-linked", "subtype": "Tetraantennary" }, { "glytoucan_ac": "G54555CN", "type": "O-linked", "subtype": "Core 3" }, { "glytoucan_ac": "G54556LG", "type": "N-linked", "subtype": "Tetraantennary" }, { "glytoucan_ac": "G54575IS", "type": "N-linked", "subtype": "Core-fucosylated" }, { "glytoucan_ac": "G54590FS", "type": "N-linked", "subtype": "Triantennary" }, { "glytoucan_ac": "G54599TH", "type": "N-linked", "subtype": "Triantennary" }, { "glytoucan_ac": "G54634UE", "type": "N-linked", "subtype": "Hybrid" }, { "glytoucan_ac": "G54716GM", "type": "N-linked", "subtype": "Tetraantennary" }, { "glytoucan_ac": "G54741SP", "type": "O-linked", "subtype": "Core 3" }, { "glytoucan_ac": "G54956ME", "type": "N-linked", "subtype": "Core-fucosylated" }, { "glytoucan_ac": "G54970OI", "type": "Other", "subtype": "Other" }, { "glytoucan_ac": "G55015QS", "type": "N-linked", "subtype": "Complex" }, { "glytoucan_ac": "G55020XV", "type": "N-linked", "subtype": "Complex" }, { "glytoucan_ac": "G55043JL", "type": "O-linked", "subtype": "Core 2" }, { "glytoucan_ac": "G55144QZ", "type": "O-linked", "subtype": "Core 4" }, { "glytoucan_ac": "G55146EO", "type": "O-linked", "subtype": "Core 3" }, { "glytoucan_ac": "G55157XP", "type": "N-linked", "subtype": "Complex" }, { "glytoucan_ac": "G55251MD", "type": "N-linked", "subtype": "Other" }, { "glytoucan_ac": "G55302QK", "type": "N-linked", "subtype": "Triantennary" }, { "glytoucan_ac": "G55360MM", "type": "N-linked", "subtype": "Triantennary" }, { "glytoucan_ac": "G55414RN", "type": "N-linked", "subtype": "Complex" }, { "glytoucan_ac": "G55481KF", "type": "N-linked", "subtype": "Core-fucosylated" }, { "glytoucan_ac": "G55508HJ", "type": "N-linked", "subtype": "Tetraantennary" }, { "glytoucan_ac": "G55630OZ", "type": "N-linked", "subtype": "Triantennary" }, { "glytoucan_ac": "G55638XL", "type": "O-linked", "subtype": "Core 2" }, { "glytoucan_ac": "G55645TD", "type": "N-linked", "subtype": "Tetraantennary" }, { "glytoucan_ac": "G55719AB", "type": "N-linked", "subtype": "Tetraantennary" }, { "glytoucan_ac": "G55803NG", "type": "N-linked", "subtype": "Core-fucosylated" }, { "glytoucan_ac": "G55818EE", "type": "N-linked", "subtype": "Core-fucosylated" }, { "glytoucan_ac": "G55827GK", "type": "N-linked", "subtype": "Tetraantennary" }, { "glytoucan_ac": "G55867TY", "type": "N-linked", "subtype": "Tetraantennary" }, { "glytoucan_ac": "G55890VR", "type": "N-linked", "subtype": "Tetraantennary" }, { "glytoucan_ac": "G55959FD", "type": "N-linked", "subtype": "Tetraantennary" }, { "glytoucan_ac": "G56095ZZ", "type": "N-linked", "subtype": "Complex" }, { "glytoucan_ac": "G56147VV", "type": "N-linked", "subtype": "Triantennary" }, { "glytoucan_ac": "G56163DR", "type": "N-linked", "subtype": "Core-fucosylated" }, { "glytoucan_ac": "G56186MJ", "type": "O-linked", "subtype": "Core 2" }, { "glytoucan_ac": "G56246PC", "type": "N-linked", "subtype": "Triantennary" }, { "glytoucan_ac": "G56293JI", "type": "O-linked", "subtype": "Core 4" }, { "glytoucan_ac": "G56318NV", "type": "N-linked", "subtype": "Tetraantennary" }, { "glytoucan_ac": "G56354PO", "type": "N-linked", "subtype": "Tetraantennary" }, { "glytoucan_ac": "G56408DR", "type": "N-linked", "subtype": "Tetraantennary" }, { "glytoucan_ac": "G56418NV", "type": "O-linked", "subtype": "Core 2" }, { "glytoucan_ac": "G56485SI", "type": "N-linked", "subtype": "Tetraantennary" }, { "glytoucan_ac": "G56492JP", "type": "N-linked", "subtype": "Core-fucosylated" }, { "glytoucan_ac": "G56499YQ", "type": "N-linked", "subtype": "Triantennary" }, { "glytoucan_ac": "G56516KW", "type": "N-linked", "subtype": "Triantennary" }, { "glytoucan_ac": "G56529CD", "type": "O-linked", "subtype": "Core 4" }, { "glytoucan_ac": "G56546LQ", "type": "N-linked", "subtype": "Triantennary" }, { "glytoucan_ac": "G56549DH", "type": "N-linked", "subtype": "Triantennary" }, { "glytoucan_ac": "G56577TY", "type": "N-linked", "subtype": "Core-fucosylated" }, { "glytoucan_ac": "G56586OT", "type": "N-linked", "subtype": "Core-fucosylated" }, { "glytoucan_ac": "G56616DG", "type": "N-linked", "subtype": "Complex" }, { "glytoucan_ac": "G56657CK", "type": "N-linked", "subtype": "Complex" }, { "glytoucan_ac": "G56691CA", "type": "N-linked", "subtype": "Complex" }, { "glytoucan_ac": "G56696EG", "type": "N-linked", "subtype": "Triantennary" 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"type": "N-linked", "subtype": "Complex" }, { "glytoucan_ac": "G57955DP", "type": "N-linked", "subtype": "Triantennary" }, { "glytoucan_ac": "G57960MN", "type": "N-linked", "subtype": "Triantennary" }, { "glytoucan_ac": "G57970NA", "type": "N-linked", "subtype": "Triantennary" }, { "glytoucan_ac": "G57999XS", "type": "N-linked", "subtype": "Triantennary" }, { "glytoucan_ac": "G58004KD", "type": "N-linked", "subtype": "Tetraantennary" }, { "glytoucan_ac": "G58029XR", "type": "N-linked", "subtype": "Triantennary" }, { "glytoucan_ac": "G58111YY", "type": "N-linked", "subtype": "Triantennary" }, { "glytoucan_ac": "G58194JW", "type": "N-linked", "subtype": "Tetraantennary" }, { "glytoucan_ac": "G58201OX", "type": "O-linked", "subtype": "Core 2" }, { "glytoucan_ac": "G58216EF", "type": "N-linked", "subtype": "Triantennary" }, { "glytoucan_ac": "G58217PP", "type": "N-linked", "subtype": "Triantennary" }, { "glytoucan_ac": "G58236FD", "type": "N-linked", "subtype": "Complex" }, { 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"Triantennary" }, { "glytoucan_ac": "G66765ZA", "type": "N-linked", "subtype": "Triantennary" }, { "glytoucan_ac": "G66846ML", "type": "N-linked", "subtype": "Tetraantennary" }, { "glytoucan_ac": "G66852CE", "type": "N-linked", "subtype": "Core-fucosylated" }, { "glytoucan_ac": "G66887YI", "type": "O-linked", "subtype": "Core 2" }, { "glytoucan_ac": "G66932MV", "type": "N-linked", "subtype": "Triantennary" }, { "glytoucan_ac": "G66942CJ", "type": "N-linked", "subtype": "Triantennary" }, { "glytoucan_ac": "G66961CH", "type": "N-linked", "subtype": "Tetraantennary" }, { "glytoucan_ac": "G66964CR", "type": "N-linked", "subtype": "Triantennary" }, { "glytoucan_ac": "G66979VI", "type": "N-linked", "subtype": "Triantennary" }, { "glytoucan_ac": "G66991YE", "type": "O-linked", "subtype": "Core 4" }, { "glytoucan_ac": "G67031FP", "type": "N-linked", "subtype": "Complex" }, { "glytoucan_ac": "G67042FO", "type": "N-linked", "subtype": "Tetraantennary" }, { "glytoucan_ac": "G67076JN", "type": 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"G67621UV", "type": "N-linked", "subtype": "Tetraantennary" }, { "glytoucan_ac": "G67623NK", "type": "N-linked", "subtype": "Triantennary" }, { "glytoucan_ac": "G67642SS", "type": "N-linked", "subtype": "Triantennary" }, { "glytoucan_ac": "G67646EV", "type": "N-linked", "subtype": "Hybrid" }, { "glytoucan_ac": "G67662PT", "type": "N-linked", "subtype": "Triantennary" }, { "glytoucan_ac": "G67693JC", "type": "O-linked", "subtype": "Core 2" }, { "glytoucan_ac": "G67719WQ", "type": "N-linked", "subtype": "Core-fucosylated" }, { "glytoucan_ac": "G67775HG", "type": "O-linked", "subtype": "Core 2" }, { "glytoucan_ac": "G67783LJ", "type": "N-linked", "subtype": "Tetraantennary" }, { "glytoucan_ac": "G67883AD", "type": "O-linked", "subtype": "Core 2" }, { "glytoucan_ac": "G67898UK", "type": "N-linked", "subtype": "Triantennary" }, { "glytoucan_ac": "G67917AQ", "type": "N-linked", "subtype": "Bisected" }, { "glytoucan_ac": "G67920QO", "type": "O-linked", "subtype": "Core 2" }, { "glytoucan_ac": "G67966WT", "type": "N-linked", "subtype": "Triantennary" }, { "glytoucan_ac": "G67978NC", "type": "N-linked", "subtype": "Tetraantennary" }, { "glytoucan_ac": "G67996UU", "type": "N-linked", "subtype": "Bisected" }, { "glytoucan_ac": "G68026AP", "type": "N-linked", "subtype": "Tetraantennary" }, { "glytoucan_ac": "G68059HB", "type": "N-linked", "subtype": "Complex" }, { "glytoucan_ac": "G68060HU", "type": "N-linked", "subtype": "Complex" }, { "glytoucan_ac": "G68080UR", "type": "N-linked", "subtype": "Triantennary" }, { "glytoucan_ac": "G68203DZ", "type": "N-linked", "subtype": "Tetraantennary" }, { "glytoucan_ac": "G68318SH", "type": "N-linked", "subtype": "Complex" }, { "glytoucan_ac": "G68337CZ", "type": "N-linked", "subtype": "Tetraantennary" }, { "glytoucan_ac": "G68344QJ", "type": "N-linked", "subtype": "Complex" }, { "glytoucan_ac": "G68391RZ", "type": "O-linked", "subtype": "Core 2" }, { "glytoucan_ac": "G68442BQ", "type": "N-linked", "subtype": "Core-fucosylated" }, { 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"Core-fucosylated" }, { "glytoucan_ac": "G69052CM", "type": "Other", "subtype": "Other" }, { "glytoucan_ac": "G69065FL", "type": "O-linked", "subtype": "Core 4" }, { "glytoucan_ac": "G69089FP", "type": "N-linked", "subtype": "Triantennary" }, { "glytoucan_ac": "G69113LL", "type": "N-linked", "subtype": "Core-fucosylated" }, { "glytoucan_ac": "G69121YI", "type": "N-linked", "subtype": "Core-fucosylated" }, { "glytoucan_ac": "G69163UZ", "type": "N-linked", "subtype": "Hybrid" }, { "glytoucan_ac": "G69170UT", "type": "N-linked", "subtype": "Triantennary" }, { "glytoucan_ac": "G69332JU", "type": "N-linked", "subtype": "Core-fucosylated" }, { "glytoucan_ac": "G69381LS", "type": "N-linked", "subtype": "Triantennary" }, { "glytoucan_ac": "G69479HX", "type": "N-linked", "subtype": "Triantennary" }, { "glytoucan_ac": "G69533GA", "type": "N-linked", "subtype": "Core-fucosylated" }, { "glytoucan_ac": "G69576GO", "type": "N-linked", "subtype": "Core-fucosylated" }, { "glytoucan_ac": "G69622NY", 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"type": "N-linked", "subtype": "Triantennary" }, { "glytoucan_ac": "G71405MT", "type": "N-linked", "subtype": "Triantennary" }, { "glytoucan_ac": "G71409LF", "type": "O-linked", "subtype": "Core 4" }, { "glytoucan_ac": "G71426FU", "type": "N-linked", "subtype": "Tetraantennary" }, { "glytoucan_ac": "G71442FU", "type": "N-linked", "subtype": "Complex" }, { "glytoucan_ac": "G71704AG", "type": "N-linked", "subtype": "Triantennary" }, { "glytoucan_ac": "G71713QS", "type": "O-linked", "subtype": "Core 2" }, { "glytoucan_ac": "G71765ZO", "type": "N-linked", "subtype": "Core-fucosylated" }, { "glytoucan_ac": "G71906BW", "type": "N-linked", "subtype": "Tetraantennary" }, { "glytoucan_ac": "G71923IX", "type": "N-linked", "subtype": "Triantennary" }, { "glytoucan_ac": "G72083DS", "type": "N-linked", "subtype": "Tetraantennary" }, { "glytoucan_ac": "G72107SE", "type": "N-linked", "subtype": "Tetraantennary" }, { "glytoucan_ac": "G72112RK", "type": "N-linked", "subtype": "Triantennary" }, { 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"N-linked", "subtype": "Tetraantennary" }, { "glytoucan_ac": "G99714FV", "type": "N-linked", "subtype": "Complex" }, { "glytoucan_ac": "G99729IU", "type": "N-linked", "subtype": "Triantennary" }, { "glytoucan_ac": "G99730GF", "type": "O-linked", "subtype": "Core 2" }, { "glytoucan_ac": "G99738HT", "type": "O-linked", "subtype": "Core 2" }, { "glytoucan_ac": "G99801VV", "type": "N-linked", "subtype": "Triantennary" }, { "glytoucan_ac": "G99866WK", "type": "N-linked", "subtype": "Triantennary" }, { "glytoucan_ac": "G99891PR", "type": "N-linked", "subtype": "Tetraantennary" }, { "glytoucan_ac": "G99896CG", "type": "N-linked", "subtype": "Triantennary" }, { "glytoucan_ac": "G99943EE", "type": "N-linked", "subtype": "Tetraantennary" }, { "glytoucan_ac": "G99954GW", "type": "N-linked", "subtype": "Core-fucosylated" }, { "glytoucan_ac": "G99954ZJ", "type": "N-linked", "subtype": "Core-fucosylated" }, { "glytoucan_ac": "G99956MJ", "type": "N-linked", "subtype": "Tetraantennary" }, { "glytoucan_ac": "G99987ZQ", "type": "O-linked", "subtype": "Core 2" } ], "enzyme_annotation": [ { "ec_number": "2.4.3.2", "ec_name": "a ganglioside GM1 (d18:1(4E)) + CMP-N-acetyl-beta-neuraminate = a ganglioside GD1a (d18:1(4E)) + CMP + H(+).", "evidence": [ { "id": "2.4.3.2", "database": "Rhea", "url": "https://www.rhea-db.org/rhea/?query=ec:2.4.3.2" }, { "id": "2.4.3.2", "database": "BRENDA Enzymes", "url": "https://www.brenda-enzymes.org/enzyme.php?ecno=2.4.3.2" } ] }, { "ec_number": "2.4.3.4", "ec_name": "a beta-D-galactosyl-(1->3)-N-acetyl-alpha-D-galactosaminyl derivative + CMP-N-acetyl-beta-neuraminate = an N-acetyl-alpha-neuraminyl-(2->3)-beta-D-galactosyl-(1->3)-N-acetyl-alpha-D-galactosaminyl derivative + CMP + H(+).", "evidence": [ { "id": "2.4.3.4", "database": "Rhea", "url": "https://www.rhea-db.org/rhea/?query=ec:2.4.3.4" }, { "id": "2.4.3.4", "database": "BRENDA Enzymes", "url": "https://www.brenda-enzymes.org/enzyme.php?ecno=2.4.3.4" } ] }, { "ec_number": "2.4.3.6", "ec_name": "a beta-D-galactosyl-(1->4)-N-acetyl-beta-D-glucosaminyl derivative + CMP-N-acetyl-beta-neuraminate = an N-acetyl-alpha-neuraminyl-(2->3)-beta-D-galactosyl-(1->4)-N-acetyl-beta-D-glucosaminyl derivative + CMP + H(+).", "evidence": [ { "id": "2.4.3.6", "database": "Rhea", "url": "https://www.rhea-db.org/rhea/?query=ec:2.4.3.6" }, { "id": "2.4.3.6", "database": "BRENDA Enzymes", "url": "https://www.brenda-enzymes.org/enzyme.php?ecno=2.4.3.6" } ] } ], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 153, "end_pos": 155 }, { "start_pos": 223, "end_pos": 225 }, { "start_pos": 402, "end_pos": 404 }, { "start_pos": 421, "end_pos": 423 }, { "start_pos": 57, "end_pos": 59 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { 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"yes" } }, { "uniprot_canonical_ac": "A0AAA9TSR1-1", "uniprot_ac": "A0AAA9TSR1", "uniprot_id": "A0AAA9TSR1_BOVIN", "mass": { "chemical_mass": 87007.0, "monoisotopic_mass": 87007.0 }, "refseq": { "ac": "XP_024844279", "name": "EF-hand domain-containing family member C2 isoform X2", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_024844279" }, "gene_names": [ { "name": "EFHC2", "type": "recommended", "evidence": [ { "id": "A0AAA9TSR1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TSR1" } ] }, { "name": "EFHC2", "type": "synonym", "evidence": [ { "id": "XP_024844279", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_024844279" } ] } ], "protein_names": [ { "name": "EF-hand domain-containing family member C2", "type": "recommended", "evidence": [ { "id": "A0AAA9TSR1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TSR1/entry#names_and_taxonomy" } ] }, { "name": "EF-hand domain-containing family member C2 isoform X2", "type": "synonym", "evidence": [ { "id": "XP_024844279", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_024844279" } ] } ], "function": [ { "annotation": "Microtubule inner protein (MIP) part of the dynein-decorated doublet microtubules (DMTs) in cilia axoneme, which is required for motile cilia beating.", "evidence": [ { "database": "UniProtKB", "id": "A0AAA9RTX7", "url": "https://www.uniprot.org/uniprotkb/A0AAA9RTX7#function" }, { "database": "UniProtKB", "id": "ARBA00035003", "url": "https://www.uniprot.org/uniprotkb/ARBA00035003#function" }, { "database": "UniProtKB", "id": "A0AAA9TP75", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TP75#function" }, { "database": "UniProtKB", "id": "A0AAA9TSR1", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TSR1#function" }, { "database": "UniProtKB", "id": "A0AAF7A5F4", "url": "https://www.uniprot.org/uniprotkb/A0AAF7A5F4#function" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Bos taurus", "taxid": 9913, "evidence": [ { "database": "UniProtKB", "id": "A0AAA9TSR1", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TSR1" } ], "common_name": "Bovine", "glygen_name": "Bovine", "reference_species": "Bos taurus [9913]" } ], "gene": [ { "name": "EFHC2", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TSR1", "locus": { "chromosome": "X", "start_pos": 99487771, "end_pos": 99248237, "strand": "-", "evidence": [ { "database": "Ensembl Gene", "id": "ENSBTAG00000053072", "url": "https://www.ensembl.org/id/ENSBTAG00000053072" } ] } } ], "crossref": [ { "id": "A0AAA9TSR1", "url": "https://alphafold.ebi.ac.uk/entry/A0AAA9TSR1", "database": "AlphaFoldDB", "categories": [] }, { "id": "100336399", "url": "https://www.ncbi.nlm.nih.gov/gene/100336399", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR006602", "url": "https://www.ebi.ac.uk/interpro/entry/IPR006602", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR011992", "url": "https://www.ebi.ac.uk/interpro/entry/IPR011992", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR040193", "url": "https://www.ebi.ac.uk/interpro/entry/IPR040193", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "PTHR12086", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR12086", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR12086:SF11", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR12086:SF11", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF06565", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF06565", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "XP_024844279", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_024844279", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0AAA9RTX7", "url": "https://www.uniprot.org/uniprotkb/A0AAA9RTX7", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0AAA9RTX7-1", "url": "https://www.uniprot.org/uniprotkb/A0AAA9RTX7-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0AAA9TP75", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TP75", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0AAA9TP75-1", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TP75-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0AAA9TSR1", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TSR1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0AAA9TSR1-1", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TSR1-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0AAF7A5F4", "url": "https://www.uniprot.org/uniprotkb/A0AAF7A5F4", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0AAF7A5F4-1", "url": "https://www.uniprot.org/uniprotkb/A0AAF7A5F4-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MALPLLPGNNFNRNMGKEKFHKSQHWGFCNNVRMLVGEDKPGIGGELLFGQKIKPKYSVFPKGMGTDSPSWVAFDKQVLSFDAYLEDEVPDKSQENYRIRRYKIYFYLEDDTVEVNEPVLQNSGLPQGIFIRRHRISLPPPNEDQFYTVHHFNVNTDIVFYGRTFKVYDCDAFTKNFLTKIGVKLNPPGQCPEDPYMKTRREKLDCMEPICPYESFDTLKQFLEYDRKVLRFFCVWDDSGSVFGDRRELILHYFLSDDTIEIKEVLPHNSGRDAMSLFLQRRKLPKYGPPGVYQPGQLTDQTVLNVYGGYSETRVYGFLLDKYQLGKLDQEFYKDTDLSIGTTINVWGRKVLLCDCDDFTKTYYRTKYGIENFTSIPCKAPSPPKIERKFPPYTGFGSEEDSLRSCIGLMPTPHQRNFKKFIEFDSYGNISNTLRFFAKLITHKCADVERMFVISYFLSDDTISVFEPIERNSGYTGGMFLKRVRVKKPGQEVFKSEFSEYIKAEELYVGAKVNVNGYLFFLVNADEYTLNYMERNSDKFPLSSIELVIQKLKEEECKSRELKQVFTAADCMHTKMVDFNTFREIMMNLTVGKLTDQEVITIARRYRVPEDPCPHRNVLVAQAHEQLKKNAFENFERLIAMCVYEDREKKKVLPSKDIKRLCKSSRLPLNEDLLGSLLSGFEDSEKQINYESFFCALNWRVNPVPVLEVASYIKERCEDEWLGMPSPIPVKYIYYLNLLKDVFGVDE", "length": 747, "header": "tr|A0AAA9TSR1-1|A0AAA9TSR1_BOVIN Isoform 1 of EF-hand domain-containing family member C2 OS=Bos taurus OX=9913 GN=EFHC2 PE=4 SV=1 CANONICAL=A0AAA9TSR1-1" }, "isoforms": [ { "isoform_ac": "A0AAA9RTX7-1", "url": "https://www.uniprot.org/uniprotkb/A0AAA9RTX7/entry", "sequence": { "sequence": "MALPLLPGNNFNRNMGKEKFHKSQHWGFCNNVRMLVGEDKPGIGGELLFGQKIKPKYSVFPKGMGTDSPSWVAFDKQVLSFDAYLEDEVPDKSQENYRIRRYKIYFYLEDDTVEVNEPVLQNSGLPQGIFIRRHRISLPPPNEDQFYTVHHFNVNTDIVFYGRTFKVYDCDAFTKNFLTKIGVKLNPPGQCPEDPYMKTRREKLDCMEPICPYESFDTLKQFLEYDRKVLRFFCVWDDSGSVFGDRRELILHYFLSDDTIEIKEVLPHNSGRDAMSLFLQRRKLPKYGPPGVYQPGQLTDQTVLNVYGGYSETRVYGFLLDKYQLGKLDQEFYKDTDLSIGTTINVWGRKVLLCDCDDFTKTYYRTKYGIENFTSIPCKAPSPPKIERKFPPYTGFGSEEDSLRSCIGLMPTPHQRNFKKFIEFDSYGNISNTLRFFAKLITHKCADVERMFVISYFLSDDTISVFEPIERNSGYTGGMFLKRVRVKKPGQEVFKSEFSEYIKAEELYVGAKVNVNGYLFFLVNADEYTLNYMERNSDKFPLSSIELVIQKLKEEECKSRELKQVFTAADCMHTKMVDFNTFREIMMNLTVGKLTDQEVITIARRYRVPEDPCPHRNVLVAQAHEQLKKNAFENFERLIAMCVYEDREKKKVLPSKDIKRLCKSSRLPLNEDLLGSLLSGDVKMSGLECHHLFL", "length": 694, "header": "tr|A0AAA9RTX7-1|A0AAA9TSR1_BOVIN Computationally mapped isoform of EF-hand domain-containing family member C2 OS=Bos taurus OX=9913 GN=EFHC2 PE=4 SV=1 CANONICAL=A0AAA9TSR1-1" }, "locus": { "chromosome": "X", "start_pos": 99487346, "end_pos": 99248388, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000093033.1", "url": "https://www.ensembl.org/id/ENSBTAT00000093033.1" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000076546.1", "url": "https://www.ensembl.org/id/ENSBTAP00000076546.1" } ] } }, { "isoform_ac": "A0AAA9TP75-1", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TP75/entry", "sequence": { "sequence": "MLSSLCSQVVQHFPLLLEHFQTPVIIILLLFSVSFTELKYGGNLVTVQEIMVNLWPLKLGSVLSFDAYLEDEVPDKSQENYRIRRYKIYFYLEDDTVEVNEPVLQNSGLPQGIFIRRHRISLPPPNEDQFYTVHHFNVNTDIVFYGRTFKVYDCDAFTKNFLTKIGVKLNPPGQCPEDPYMKTRREKLDCMEPICPYESFDTLKQFLEYDRKVLRFFCVWDDSGSVFGDRRELILHYFLSDDTIEIKEVLPHNSGRDAMSLFLQRRKLPKYGPPGVYQPGQLTDQTVLNVYGGYSETRVYGFLLDKYQLGKLDQEFYKDTDLSIGTTINVWGRKVLLCDCDDFTKTYYRTKYGIENFTSIPCKAPSPPKIERKFPPYTGFGSEEDSLRSCIGLMPTPHQRNFKKFIEFDSYGNISNTLRFFAKLITHKCADVERMFVISYFLSDDTISVFEPIERNSGYTGGMFLKRVRVKKPGQEVFKSEFSEYIKAEELYVGAKVNVNGYLFFLVNADEYTLNYMERNSDKFPLSSIELVIQKLKEEECKSRELKQVFTAADCMHTKMVDFNTFREIMMNLTVGKLTDQEVITIARRYRVPEDPCPHRNVLVAQAHEQLKKNAFENFERLIAMCVYEDREKKKVLPSKDIKRLCKSSRLPLNEDLLGSLLSGFEDSEKQINYESFFCALNWRVNPVPVLEVASYIKERCEDEWLGMPSPIPVKYIYYLNLLKDVFGVDE", "length": 731, "header": "tr|A0AAA9TP75-1|A0AAA9TSR1_BOVIN Computationally mapped isoform of EF-hand domain-containing family member C2 OS=Bos taurus OX=9913 GN=EFHC2 PE=4 SV=1 CANONICAL=A0AAA9TSR1-1" }, "locus": { "chromosome": "X", "start_pos": 99487399, "end_pos": 99304345, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000090692.1", "url": "https://www.ensembl.org/id/ENSBTAT00000090692.1" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000099061.1", "url": "https://www.ensembl.org/id/ENSBTAP00000099061.1" } ] } }, { "isoform_ac": "A0AAA9TSR1-1", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TSR1/entry", "sequence": { "sequence": "MALPLLPGNNFNRNMGKEKFHKSQHWGFCNNVRMLVGEDKPGIGGELLFGQKIKPKYSVFPKGMGTDSPSWVAFDKQVLSFDAYLEDEVPDKSQENYRIRRYKIYFYLEDDTVEVNEPVLQNSGLPQGIFIRRHRISLPPPNEDQFYTVHHFNVNTDIVFYGRTFKVYDCDAFTKNFLTKIGVKLNPPGQCPEDPYMKTRREKLDCMEPICPYESFDTLKQFLEYDRKVLRFFCVWDDSGSVFGDRRELILHYFLSDDTIEIKEVLPHNSGRDAMSLFLQRRKLPKYGPPGVYQPGQLTDQTVLNVYGGYSETRVYGFLLDKYQLGKLDQEFYKDTDLSIGTTINVWGRKVLLCDCDDFTKTYYRTKYGIENFTSIPCKAPSPPKIERKFPPYTGFGSEEDSLRSCIGLMPTPHQRNFKKFIEFDSYGNISNTLRFFAKLITHKCADVERMFVISYFLSDDTISVFEPIERNSGYTGGMFLKRVRVKKPGQEVFKSEFSEYIKAEELYVGAKVNVNGYLFFLVNADEYTLNYMERNSDKFPLSSIELVIQKLKEEECKSRELKQVFTAADCMHTKMVDFNTFREIMMNLTVGKLTDQEVITIARRYRVPEDPCPHRNVLVAQAHEQLKKNAFENFERLIAMCVYEDREKKKVLPSKDIKRLCKSSRLPLNEDLLGSLLSGFEDSEKQINYESFFCALNWRVNPVPVLEVASYIKERCEDEWLGMPSPIPVKYIYYLNLLKDVFGVDE", "length": 747, "header": "tr|A0AAA9TSR1-1|A0AAA9TSR1_BOVIN Isoform 1 of EF-hand domain-containing family member C2 OS=Bos taurus OX=9913 GN=EFHC2 PE=4 SV=1 CANONICAL=A0AAA9TSR1-1" }, "locus": { "chromosome": "X", "start_pos": 99487399, "end_pos": 99248388, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000097794.1", "url": "https://www.ensembl.org/id/ENSBTAT00000097794.1" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000100390.1", "url": "https://www.ensembl.org/id/ENSBTAP00000100390.1" } ] } }, { "isoform_ac": "A0AAF7A5F4-1", "url": "https://www.uniprot.org/uniprotkb/A0AAF7A5F4/entry", "sequence": { "sequence": "MALPLLPGNNFNRNMGKEKFHKSQHWGFCNNVRMLVGEDKPGIGGELLFGQKIKPKYSVFPKGMGTDSPSWVAFDKQVLSFDAYLEDEVPDKSQENYRIRRYKIYFYLEDDTVEVNEPVLQNSGLPQGIFIRRHRISLPPPNEDQFYTVHHFNVNTDIVFYGRTFKVYDCDAFTKNFLTKIGVKLNPPGQCPEDPYMKTRREKLDCMEPICPYESFDTLKQFLEYDRKVLRFFCVWDDSGSVFGDRRELILHYFLSDDTIEIKEVLPHNSGRDAMSLFLQRRKLPKYGPPGVYQPGQLTDQTVLNVYGGYSETRVYGFLLDKYQLGKLDQEFYKDTDLSIGTTINVWGRKVLLCDCDDFTKTYYRTKYGIENFTSIPCKAPSPPKIERKFPPYTGFGSEEDSLRSCIGLMPTPHQRNFKKFIEFDSYGNISNTLRFFAKLITHKCADVERMFVISYFLSDDTISVFEPIERNSGYTGGMFLKRVRVKKPGQEVFKSEFSEYIKAEELYVGAKVNVNGYLFFLVNADEYTLNYMERNSDKFPLSSIELVIQKLKEEECKSRELKQVFTAADCMHTKMVDFNTFREIMMNLTVGKLTDQEVITIARRYRVPEDPCPHRNVLVAQAHEQLKKNAFENFERLIAMCVYEDREKKKVLPSKDIKRLCKSSRLPLNEDLLGSLLSGFEDSEKQINYESFFCALNWRVNPVPVLEVASYIKEVLT", "length": 718, "header": "tr|A0AAF7A5F4-1|A0AAF7A5F4_BOVIN Computationally mapped isoform of EF-hand domain-containing family member C2 OS=Bos taurus OX=9913 GN=EFHC2 PE=4 SV=1 CANONICAL=A0AAA9TSR1-1" }, "locus": { "chromosome": "X", "start_pos": 99483963, "end_pos": 99248388, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000082791.2", "url": "https://www.ensembl.org/id/ENSBTAT00000082791.2" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000063049.2", "url": "https://www.ensembl.org/id/ENSBTAP00000063049.2" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [], "orthologs": [], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 4, "go_terms": [ { "name": "axonemal microtubule", "id": "GO:0005879", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005879", "evidence": [ { "database": "UniProtKB", "id": "A0AAA9TSR1", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TSR1" } ], "pmid": "" }, { "name": "sperm flagellum", "id": "GO:0036126", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0036126", "evidence": [ { "database": "UniProtKB", "id": "A0AAA9TSR1", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TSR1" } ], "pmid": "" }, { "name": "ciliary basal body", "id": "GO:0036064", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0036064", "evidence": [ { "database": "UniProtKB", "id": "A0AAA9TSR1", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TSR1" } ], "pmid": "" }, { "name": "axonemal A tubule inner sheath", "id": "GO:0160111", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0160111", "evidence": [ { "database": "UniProtKB", "id": "A0AAA9TSR1", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TSR1" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 1, "go_terms": [ { "name": "flagellated sperm motility", "id": "GO:0030317", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030317", "evidence": [ { "database": "UniProtKB", "id": "A0AAA9TSR1", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TSR1" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 372, "end_pos": 374, "annotation": "n_glycosylation_sequon" }, { "start_pos": 429, "end_pos": 431, "annotation": "n_glycosylation_sequon" }, { "start_pos": 588, "end_pos": 590, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A0AAA9TSR1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TSR1" }, { "id": "PS51336", "database": "PROSITE", "url": "https://prosite.expasy.org/PS51336" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "DM10", "eco_id": "ECO_0000259", "start_pos": 75, "end_pos": 182, "start_aa": "Asp", "end_aa": "Gly", "glycosite_overlap": [] } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 372, "end_pos": 374 }, { "start_pos": 429, "end_pos": 431 }, { "start_pos": 588, "end_pos": 590 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": 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"table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ], "tool_support": { "graph_view": "yes" } }, { "uniprot_canonical_ac": "A0AAA9TW23-1", "uniprot_ac": "A0AAA9TW23", "uniprot_id": "A0AAA9TW23_BOVIN", "mass": { "chemical_mass": 69261.0, "monoisotopic_mass": 69261.0 }, "refseq": { "ac": "NP_001192587", "name": "uncharacterized aarF domain-containing protein kinase 2", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001192587" }, "gene_names": [ { "name": "ADCK2", "type": "recommended", "evidence": [ { "id": "A0AAA9TW23", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TW23" } ] }, { "name": "ADCK2", "type": "synonym", "evidence": [ { "id": "NP_001192587", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001192587" } ] } ], "protein_names": [ { "name": "AarF domain containing kinase 2", "type": "synonym", "evidence": [ { "id": "A0AAA9TW23", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TW23/entry#names_and_taxonomy" } ] }, { "name": "uncharacterized aarF domain-containing protein kinase 2", "type": "synonym", "evidence": [ { "id": "NP_001192587", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001192587" } ] } ], "function": [], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Bos taurus", "taxid": 9913, "evidence": [ { "database": "UniProtKB", "id": "A0AAA9TW23", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TW23" } ], "common_name": "Bovine", "glygen_name": "Bovine", "reference_species": "Bos taurus [9913]" } ], "gene": [ { "name": "ADCK2", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TW23", "locus": { "chromosome": "4", "start_pos": 104009670, "end_pos": 103994556, "strand": "-", "evidence": [ { "database": "Ensembl Gene", "id": "ENSBTAG00000020484", "url": "https://www.ensembl.org/id/ENSBTAG00000020484" } ] } } ], "crossref": [ { "id": "A0AAA9TW23", "url": "https://alphafold.ebi.ac.uk/entry/A0AAA9TW23", "database": "AlphaFoldDB", "categories": [] }, { "id": "cd13971", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd13971", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "539345", "url": "https://www.ncbi.nlm.nih.gov/gene/539345", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR004147", "url": "https://www.ebi.ac.uk/interpro/entry/IPR004147", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR011009", "url": "https://www.ebi.ac.uk/interpro/entry/IPR011009", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR044095", "url": "https://www.ebi.ac.uk/interpro/entry/IPR044095", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR052402", "url": "https://www.ebi.ac.uk/interpro/entry/IPR052402", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "bta:539345", "url": "https://www.genome.jp/dbget-bin/www_bget?bta:539345", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "PTHR45890", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR45890", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR45890:SF1", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR45890:SF1", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF03109", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF03109", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF27536", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF27536", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "NP_001192587", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001192587", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0AAA9RUN3", "url": "https://www.uniprot.org/uniprotkb/A0AAA9RUN3", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0AAA9RUN3-1", "url": "https://www.uniprot.org/uniprotkb/A0AAA9RUN3-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0AAA9TW23", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TW23", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0AAA9TW23-1", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TW23-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MVTPWRFSLRVCLAHLRGFALRKEVGLLRHSGGCRKARLCWLLLGTLPKLVSTCEDIGEGAPESVRRQTTSWSDLAKNGPLERVPPEGRLGWLLLHVRIWLRAGALLVKFFPLLLLYPLTYLAPSVSSLWLHLLLKATETSGPTYIKLGQWASTRRDLFSEAFCAQFSRLHVQVSPHPWTHTEHILRQAFGEDWGRVLCFEKQEPVGSGCVAQVYKARANPAFLENDSIQRLATASILQFSETGAAGGLGELSGRLEKAGRPQESLADQSFVERLLFPKPDLVGSNASLSQASGTAHEQEPDHLVPVAVKVLHPGLLAQVQMDLLLMKMGSRVLTVLPGIKWLSLPEIVEEFEKLMVQQIDLRYEARNLELFQCNFLNVNSVKFPTPLRPFVTKDVLVETYEESVPVSSYQHAGIPLDVKRKIARLGINMLLKMIFVDNFVHADLHPGNILVQGADGLAQGPEARLQPVDVCEALVVAVSPARCPLRLVLLDAGIVAELQAADLRNFRAVFMAVAMGQGQRVAELILHHARASECEDVEGFKAEMARLVTQARKNTITLEKLQVSSLLSNVFKLLMTHKVKLESNFASIVFAIMVLEGLGRSLDPKLDILEAAKPFLLKGLVTSR", "length": 625, "header": "tr|A0AAA9TW23-1|A0AAA9TW23_BOVIN Isoform 1 of AarF domain containing kinase 2 OS=Bos taurus OX=9913 GN=ADCK2 PE=3 SV=2 CANONICAL=A0AAA9TW23-1" }, "isoforms": [ { "isoform_ac": "A0AAA9RUN3-1", "url": "https://www.uniprot.org/uniprotkb/A0AAA9RUN3/entry", "sequence": { "sequence": "MVTPWRFSLRVCLAHLRGFALRKEVGLLRHSGGCRKARLCWLLLGTLPKLVSTCEDIGEGAPESVRRQTTSWSDLAKNGPLERVPPEGRLGWLLLHVRIWLRAGALLVKFFPLLLLYPLTYLAPSVSSLWLHLLLKATETSGPTYIKLGQWASTRRDLFSEAFCAQFSRLHVQVSPHPWTHTEHILRQAFGEDWGRVLCFEKQEPVGSGCVAQVYKARANPAFLENDSIQRLATASILQFSETGAAGGLGELSGRLEKAGRPQESLADQSFVERLLFPKPDLVGSNASLSQASGTAHEQEPDHLVPVAVKVLHPGLLAQVQMDLLLMKMGSRVLTVLPGIKWLSLPEIVEEFEKLMVQQIDLRYEARNLELFQCNFLNVNSVKFPTPLRPFVTKDVLVETYEESVPVSSYQHAGIPLDVKRKIARLGINMLLKMIFVDNFVHADLHPGNILVQGADGLAQGPEARLQPVDVCEALVVAVSPARCPLRLVLLDAGIVAELQAADLRNFRAVFMAVAMGQGQRVAELILHHARASECEDVEGFKAEMARLVTQARKNTITLEKVKLESNFASIVFAIMVLEGLGRSLDPKLDILEAAKPFLLKGLVTSR", "length": 607, "header": "tr|A0AAA9RUN3-1|A0AAA9TW23_BOVIN Computationally mapped isoform of AarF domain containing kinase 2 OS=Bos taurus OX=9913 GN=ADCK2 PE=3 SV=1 CANONICAL=A0AAA9TW23-1" }, "locus": { "chromosome": "4", "start_pos": 104008666, "end_pos": 103994755, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000093931.2", "url": "https://www.ensembl.org/id/ENSBTAT00000093931.2" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000074646.1", "url": "https://www.ensembl.org/id/ENSBTAP00000074646.1" } ] } }, { "isoform_ac": "A0AAA9TW23-1", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TW23/entry", "sequence": { "sequence": "MVTPWRFSLRVCLAHLRGFALRKEVGLLRHSGGCRKARLCWLLLGTLPKLVSTCEDIGEGAPESVRRQTTSWSDLAKNGPLERVPPEGRLGWLLLHVRIWLRAGALLVKFFPLLLLYPLTYLAPSVSSLWLHLLLKATETSGPTYIKLGQWASTRRDLFSEAFCAQFSRLHVQVSPHPWTHTEHILRQAFGEDWGRVLCFEKQEPVGSGCVAQVYKARANPAFLENDSIQRLATASILQFSETGAAGGLGELSGRLEKAGRPQESLADQSFVERLLFPKPDLVGSNASLSQASGTAHEQEPDHLVPVAVKVLHPGLLAQVQMDLLLMKMGSRVLTVLPGIKWLSLPEIVEEFEKLMVQQIDLRYEARNLELFQCNFLNVNSVKFPTPLRPFVTKDVLVETYEESVPVSSYQHAGIPLDVKRKIARLGINMLLKMIFVDNFVHADLHPGNILVQGADGLAQGPEARLQPVDVCEALVVAVSPARCPLRLVLLDAGIVAELQAADLRNFRAVFMAVAMGQGQRVAELILHHARASECEDVEGFKAEMARLVTQARKNTITLEKLQVSSLLSNVFKLLMTHKVKLESNFASIVFAIMVLEGLGRSLDPKLDILEAAKPFLLKGLVTSR", "length": 625, "header": "tr|A0AAA9TW23-1|A0AAA9TW23_BOVIN Isoform 1 of AarF domain containing kinase 2 OS=Bos taurus OX=9913 GN=ADCK2 PE=3 SV=2 CANONICAL=A0AAA9TW23-1" }, "locus": { "chromosome": "4", "start_pos": 104008666, "end_pos": 103994755, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000090044.2", "url": "https://www.ensembl.org/id/ENSBTAT00000090044.2" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000101629.2", "url": "https://www.ensembl.org/id/ENSBTAP00000101629.2" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [ { "id": "bta:539345", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?bta:539345", "resource": "KEGG Pathway" } ], "orthologs": [], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 1, "go_terms": [ { "name": "mitochondrion", "id": "GO:0005739", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005739", "evidence": [ { "database": "UniProtKB", "id": "A0AAA9TW23", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TW23" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 1, "go_terms": [ { "name": "regulation of ubiquinone biosynthetic process", "id": "GO:0010795", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0010795", "evidence": [ { "database": "UniProtKB", "id": "A0AAA9TW23", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TW23" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 226, "end_pos": 228, "annotation": "n_glycosylation_sequon" }, { "start_pos": 286, "end_pos": 288, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A0AAA9TW23", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TW23" }, { "id": "PF03109", "database": "Pfam", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF03109" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "ABC1 atypical kinase-like", "eco_id": "ECO_0000259", "start_pos": 306, "end_pos": 525, "start_aa": "Pro", "end_aa": "Leu", "glycosite_overlap": [] } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 226, "end_pos": 228 }, { "start_pos": 286, "end_pos": 288 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ], "tool_support": { "graph_view": "yes" } }, { "uniprot_canonical_ac": "A0AAA9TV71-1", "uniprot_ac": "A0AAA9TV71", "uniprot_id": "A0AAA9TV71_BOVIN", "mass": { "chemical_mass": 151573.0, "monoisotopic_mass": 151573.0 }, "refseq": { "ac": "XP_005223832", "name": "F-actin-uncapping protein LRRC16A isoform X4", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_005223832" }, "gene_names": [ { "name": "CARMIL1", "type": "recommended", "evidence": [ { "id": "A0AAA9TV71", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TV71" } ] }, { "name": "CARMIL1", "type": "synonym", "evidence": [ { "id": "XP_005223832", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_005223832" } ] } ], "protein_names": [ { "name": "Capping protein regulator and myosin 1 linker 1", "type": "synonym", "evidence": [ { "id": "A0AAA9TV71", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TV71/entry#names_and_taxonomy" } ] }, { "name": "F-actin-uncapping protein LRRC16A isoform X4", "type": "synonym", "evidence": [ { "id": "XP_005223832", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_005223832" } ] } ], "function": [], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Bos taurus", "taxid": 9913, "evidence": [ { "database": "UniProtKB", "id": "A0AAA9TV71", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TV71" } ], "common_name": "Bovine", "glygen_name": "Bovine", "reference_species": "Bos taurus [9913]" } ], "gene": [ { "name": "CARMIL1", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TV71", "locus": { "chromosome": "23", "start_pos": 32267101, "end_pos": 32573701, "strand": "+", "evidence": [ { "database": "Ensembl Gene", "id": "ENSBTAG00000016549", "url": "https://www.ensembl.org/id/ENSBTAG00000016549" } ] } } ], "crossref": [ { "id": "ENSBTAG00000016549", "url": "https://bgee.org/?page=gene&gene_id=ENSBTAG00000016549", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "537314", "url": "https://www.ncbi.nlm.nih.gov/gene/537314", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR001611", "url": "https://www.ebi.ac.uk/interpro/entry/IPR001611", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR011993", "url": "https://www.ebi.ac.uk/interpro/entry/IPR011993", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR031943", "url": "https://www.ebi.ac.uk/interpro/entry/IPR031943", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR032675", "url": "https://www.ebi.ac.uk/interpro/entry/IPR032675", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR041245", "url": "https://www.ebi.ac.uk/interpro/entry/IPR041245", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR051279", "url": "https://www.ebi.ac.uk/interpro/entry/IPR051279", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "bta:537314", "url": "https://www.genome.jp/dbget-bin/www_bget?bta:537314", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "KGCEERL", "url": "https://omabrowser.org/oma/group/KGCEERL/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "F1MMJ6", "url": "https://www.orthodb.org/?gene=F1MMJ6", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR24112", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR24112", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR24112:SF39", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR24112:SF39", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF13516", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF13516", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF16000", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF16000", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF17888", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF17888", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "XP_005223832", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_005223832", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0AAA9RVK9", "url": "https://www.uniprot.org/uniprotkb/A0AAA9RVK9", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0AAA9RVK9-1", "url": "https://www.uniprot.org/uniprotkb/A0AAA9RVK9-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0AAA9SUW9", "url": "https://www.uniprot.org/uniprotkb/A0AAA9SUW9", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0AAA9SUW9-1", "url": "https://www.uniprot.org/uniprotkb/A0AAA9SUW9-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0AAA9TB07", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TB07", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0AAA9TB07-1", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TB07-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0AAA9TV71", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TV71", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0AAA9TV71-1", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TV71-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "F1MMJ6", "url": "https://www.uniprot.org/uniprotkb/F1MMJ6", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "F1MMJ6-1", "url": "https://www.uniprot.org/uniprotkb/F1MMJ6-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MAEESSEVPGELIESIKDVLGRKIKIALKKKVKLEVKGDKVENRVLVLTSCRAFLVTARIPTKLEVTFSYLEIHGVICSKPAQMVVETEKCSISMKMASPEDVSEVLAHIGTNLRKIFPGLSPVRIMKKVFMEPSERLASLQALWDSQTVTEQGPCGGFSQMYACVCDWLGFSYREEVQWDVDTIYLTQDTRELNLQDFSHLDHRDLIPIIAALEYNQWFTKLSSKDLKLSTDVCEQILRVVSRSNRLEELVLENAGLRIDFAQKLASALAHNPTSGLHTINLAGNPLEDRGVSSLSIQFAKLPKGLKHLNLSKTSLSPKGVNSLSQSLSANPLTATTLVHLDLSGNILRGDDLSSMYSFLAQPNAIAHLDLSNTECSLDMVCGALLRGCLQYLAVLNLSRTVFSHRKGKEVPPSFKQFFSSSLALMQINLSGTKLSPEPLKALLLGLASNHNLKGVSLDLSNCELRSGGAQVLEGCIAEIHNISSLDISDNGLESDLSTLIVWLSKNRSIQHLALGKNFNNMKSKNLTPVLDNLVQMIQDEESPLQSLSLADSKLKTGVTIIINALGSNTSLTKVDISGNGMGDMGAKMLAKALQINTKLRTVIWDKNNITAQGFQDIAVAMEKNYTLRFMPIPMYDASQALKTNPEKTEEALQKIENYLLRNHETRKYLQEQAYRLQQGIVTSTTQQMIDRMCVKVQDHLNSLRSCEGDAVQEDLKSAERLMQDAKNSKTLLPNLYHVGSVSWAGASGLLSSPIQETLESMAGEVTRVVDEQLKALLESMVDAAENLCPNVMRKAHIRQDLIHASTEKISIPRTFVKNVLLEQSGIDILNKISEVKLTVASFLSDRIVDEILDALSHCHHKLADHFSRRGKTLLQQDSLEMELAEEKPVKRSIITVEELTEIERLEDLDTCMMTPKSKRKTIHSRMLRPVSRAFEMEFDLDKALEEVPIHIEDPPFPSIRQEKRSSGFISDLPSEEGRKLEHFTKLRPKRAKKQQSTHPAGCATSIVSQDGEQNGLMGRVDEGVDEFFTKKVTKMDSKRWSARGSESHELSEGGDEKKKRDFRKTGFLNLIKPRNKPERSSTVLTAEELSSPKAGVRSPAVDAPRKDTKPAEHNGSADRVEEIKTPDSLEESQGEDVGKVDRSDSKGSPQGGRRYGVQMMGSGLLAEMKAKQEMKAKAACSLKKLGNDAVSQDSSSLTLSSTERLDGGGAVPKVHPENRFGLGTPEKNAKADLKAEAVSKPRSFSNRPTSPKPLLQAPKPNLAARPTIPQKPRTASRPEDVPDSPSSPGSPKVALLPPVLKKVPSDKERDGQGSPQPSPRTFSREVSRRSWSQQAQECQEQKQWASSKDGQPGSKSSDSGEEAEREYIFV", "length": 1372, "header": "tr|A0AAA9TV71-1|A0AAA9TV71_BOVIN Isoform 1 of Capping protein regulator and myosin 1 linker 1 OS=Bos taurus OX=9913 GN=CARMIL1 PE=1 SV=1 CANONICAL=A0AAA9TV71-1" }, "isoforms": [ { "isoform_ac": "A0AAA9RVK9-1", "url": "https://www.uniprot.org/uniprotkb/A0AAA9RVK9/entry", "sequence": { "sequence": "MAEESSEVPGELIESIKDVLGRKIKIALKKKVKLEVKGDKVENRVLVLTSCRAFLVTARIPTKLEVTFSYLEIHGVICSKPAQMVVETEKCSISMKMASPEDVSEVLAHIGTNLRKIFPGLSPVRIMKKVFMEPSERLASLQALWDSQTVTEQGPCGGFSQMYACVCDWLGFSYREEVQWDVDTIYLTQDTRELNLQDFSHLDHRDLIPIIAALEYNQWFTKLSSKDLKLSTDVCEQILRVVSRSNRLEELVLENAGLRIDFAQKLASALAHNPTSGLHTINLAGNPLEDRGVSSLSIQFAKLPKGLKHLNLSKTSLSPKGVNSLSQSLSANPLTATTLVHLDLSGNILRGDDLSSMYSFLAQPNAIAHLDLSNTECSLDMVCGALLRGCLQYLAVLNLSRTVFSHRKGKEVPPSFKQFFSSSLALMQINLSGTKLSPEPLKALLLGLASNHNLKGVSLDLSNCELRSGGAQVLEGCIAEIHNISSLDISDNGLESDLSTLIVWLSKNRSIQHLALGKNFNNMKSKNLTPVLDNLVQMIQDEESPLQSLSLADSKLKTGVTIIINALGSNTSLTKVDISGNGMGDMGAKMLAKALQINTKLRTVIWDKNNITAQGFQDIAVAMEKNYTLRFMPIPMYDASQALKTNPEKTEEALQKMIDRMCVKVQDHLNSLRSCEGDAVQEDLKSAERLMQDAKNSKTLLPNLYHVGSVSWAGASGLLSSPIQETLESMAGEVTRVVDEQLKALLESMVDAAENLCPNVMRKAHIRQDLIHASTEKISIPRTFVKNVLLEQSGIDILNKISEVKLTVASFLSDRIVDEILDALSHCHHKLADHFSRRGKTLLQQDSLEMELAEEKPVKRSIITVEELTEIERLEDLDTCMMTPKSKRKTIHSRMLRPVSRAFEMEFDLDKALEEVPIHIEDPPFPSIRQEKRSSGFISDLPSEEGRKLEHFTKLRPKRAKKQQSTHPAGCATSIVSQDGEQNGLMGRVDEGVDEFFTKKVTKMDSKRWSARGSESHELSEGGDEKKKRDFRKTGFLNLIKPRNKPERSSTVLTAEELSSPKAGVRSPAVDAPRKDTKPAEHNGSADRVEEIKTPDSLEESQGEDVGKVDRSDSKGSPQGGRRYGVQMMGSGLLAEMKAKQEMKAKAACSLKKLGNDAVSQDSSSLTLSSTERLDGGGAVPKVHPENRFGLGTPEKNAKADLKAEAVSKPRSFSNRPTSPKPLLQAPKPNLAARPTIPQKPRTASRPEDVPDSPSSPGSPKVALLPPVLKKVPSDKERDGQGSPQPSPRTFSREVSRRSWSQQAQECQEQKQWASSKDGQPGSKSSDSGEEAEREYIFV", "length": 1339, "header": "tr|A0AAA9RVK9-1|A0AAA9TV71_BOVIN Computationally mapped isoform of Capping protein regulator and myosin 1 linker 1 OS=Bos taurus OX=9913 GN=CARMIL1 PE=1 SV=1 CANONICAL=A0AAA9TV71-1" }, "locus": { "chromosome": "23", "start_pos": 32573502, "end_pos": 32268105, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000119623.1", "url": "https://www.ensembl.org/id/ENSBTAT00000119623.1" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000075010.1", "url": "https://www.ensembl.org/id/ENSBTAP00000075010.1" } ] } }, { "isoform_ac": "A0AAA9SUW9-1", "url": "https://www.uniprot.org/uniprotkb/A0AAA9SUW9/entry", "sequence": { "sequence": "MAEESSEVPGELIESIKDVLGRKIKIALKKKVKLEVKGDKVENRVLVLTSCRAFLVTARIPTKLEVTFSYLEIHGVICSKPAQMVVETEKCSISMKMASPEDVSEVLAHIGTNLRKIFPGLSPVRIMKKVFMEPSERLASLQALWDSQTVTEQGPCGGFSQMYACVCDWLGFSYREEVQWDVDTIYLTQDTRELNLQDFSHLDHRDLIPIIAALEYNQWFTKLSSKDLKLSTDVCEQILRVVSRSNRLEELVLENAGLRIDFAQKLASALAHNPTSGLHTINLAGNPLEDRGVSSLSIQFAKLPKGLKHLNLSKTSLSPKGVNSLSQSLSANPLTATTLVHLDLSGNILRGDDLSSMYSFLAQPNAIAHLDLSNTECSLDMVCGALLRGCLQYLAVLNLSRTVFSHRKGKEVPPSFKQFFSSSLALMQINLSGTKLSPEPLKALLLGLASNHNLKGVSLDLSNCELRSGGAQVLEGCIAEIHNISSLDISDNGLESDLSTLIVWLSKNRSIQHLALGKNFNNMKSKNLTPVLDNLVQMIQDEESPLQSLSLADSKLKTGVTIIINALGSNTSLTKVDISGNGMGDMGAKMLAKALQINTKLRTVIWDKNNITAQGFQDIAVAMEKNYTLRFMPIPMYDASQALKTNPEKTEEALQKIENYLLRNHETRKYLQEQAYRLQQGIVTSTTQQMIDRMCVKVQDHLNSLRSCEGDAVQEDLKSAERLMQDAKNSKTLLPNLYHVGSVSWAGASGLLSSPIQETLESMAGEVTRVVDEQLKALLESMVDAAENLCPNVMRKAHIRQDLIHASTEKISIPRTFVKNVLLEQSGIDILNKISEVKLTVASFLSDRIVDEILDALSHCHHKLADHFSRRGKTLLQQDSLEMELAEEKPVKRSIITVEELTEIERLEDLDTCMMTPKSKRKTIHSRMLRPVSRAFEMEFDLDKALEEVPIHIEDPPFPSIRQEKRSSGFISDLPSEEGRKLEHFTKLRPKRAKKQQSTHPAGCATSIVSQDGEQNGLMGRVDEGVDEFFTKKVTKMDSKRWSARGSESHELSEGGDEKKKRDFRKTGFLNLIKPRNKPERSSTVLTAEELSSPKAGVRSPAVDAPRKDTKPAEHNGSADRVEEIKTPDSLEESQGEDVGKVDRSDSKGSPQGGRRYGVQMMGSGLLAEMKAKQEMKAKAACSLKKLGNDAVSQDSSSLTLSSTERLDGGGAVPKVHPENRFGLGTPEKNAKADLKAEAVSKPRSFSNRPTSPKPLLQAPKPNLAARPTIPQKPRTASRPEDVPDSPSSPGSPKVALLPPVLKKVPSDKERDGQGSPQPSPRTFSREVVQRGDYYKRHSDHDSGKPSGRGKRPSKLYSTIAEEEVNAIGRRKSQPTHVSRRSWSQQAQECQEQKQWASSKDGQPGSKSSDSGEEAEREYIFV", "length": 1422, "header": "tr|A0AAA9SUW9-1|A0AAA9TV71_BOVIN Computationally mapped isoform of Capping protein regulator and myosin 1 linker 1 OS=Bos taurus OX=9913 GN=CARMIL1 PE=1 SV=1 CANONICAL=A0AAA9TV71-1" }, "locus": { "chromosome": "23", "start_pos": 32573502, "end_pos": 32268105, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000122599.1", "url": "https://www.ensembl.org/id/ENSBTAT00000122599.1" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000087965.1", "url": "https://www.ensembl.org/id/ENSBTAP00000087965.1" } ] } }, { "isoform_ac": "A0AAA9TB07-1", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TB07/entry", "sequence": { "sequence": "MVLTSCRAFLVTARIPTKLEVTFSYLEIHGVICSKPAQMVVETEKCSISMKMASPEDVSEVLAHIGTNLRKIFPGLSPVRIMKKVFMEPSERLASLQALWDSQTVTEQGPCGGFSQMYACVCDWLGFSYREEVQWDVDTIYLTQDTRELNLQDFSHLDHRDLIPIIAALEYNQWFTKLSSKDLKLSTDVCEQILRVVSRSNRLEELVLENAGLRIDFAQKLASALAHNPTSGLHTINLAGNPLEDRGVSSLSIQFAKLPKGLKHLNLSKTSLSPKGVNSLSQSLSANPLTATTLVHLDLSGNILRGDDLSSMYSFLAQPNAIAHLDLSNTECSLDMVCGALLRGCLQYLAVLNLSRTVFSHRKGKEVPPSFKQFFSSSLALMQINLSGTKLSPEPLKALLLGLASNHNLKGVSLDLSNCELRSGGAQVLEGCIAEIHNISSLDISDNGLESDLSTLIVWLSKNRSIQHLALGKNFNNMKSKNLTPVLDNLVQMIQDEESPLQSLSLADSKLKTGVTIIINALGSNTSLTKVDISGNGMGDMGAKMLAKALQINTKLRTVIWDKNNITAQGFQDIAVAMEKNYTLRFMPIPMYDASQALKTNPEKTEEALQKIENYLLRNHETRKYLQEQAYRLQQGIVTSTTQQMIDRMCVKVQDHLNSLRSCEGDAVQEDLKSAERLMQDAKNSKTLLPNLYHVGSVSWAGASGLLSSPIQETLESMAGEVTRVVDEQLKALLESMVDAAENLCPNVMRKAHIRQDLIHASTEKISIPRTFVKNVLLEQSGIDILNKISEVKLTVASFLSDRIVDEILDALSHCHHKLADHFSRRGKTLLQQDSLEMELAEEKPVKRSIITVEELTEIERLEDLDTCMMTPKSKRKTIHSRMLRPVSRAFEMEFDLDKALEEVPIHIEDPPFPSIRQEKRSSGFISDLPSEEGRKLEHFTKLRPKRAKKQQSTHPAGCATSIVSQDGEQNGLMGRVDEGVDEFFTKKVTKMDSKRWSARGSESHELSEGGDEKKKRDFRKTGFLNLIKPRNKPERSSTVLTAEELSSPKAGVRSPAVDAPRKDTKPAEHNGSADRVEEIKTPDSLEESQGEDVGKVDRSDSKGSPQGGRRYGVQMMGSGLLAEMKAKQEMKAKAACSLKKLGNDAVSQDSSSLTLSSTERLDGGGAVPKVHPENRFGLGTPEKNAKADLKAEAVSKPRSFSNRPTSPKPLLQAPKPNLAARPTIPQKPRTASRPEDVPDSPSSPGSPKVALLPPVLKKVPSDKERDGQGSPQPSPRTFSREVSRRSWSQQAQECQEQKQWASSKDGQPGSKSSDSGEEAEREYIFV", "length": 1327, "header": "tr|A0AAA9TB07-1|A0AAA9TV71_BOVIN Computationally mapped isoform of Capping protein regulator and myosin 1 linker 1 OS=Bos taurus OX=9913 GN=CARMIL1 PE=1 SV=1 CANONICAL=A0AAA9TV71-1" }, "locus": { "chromosome": "23", "start_pos": 32517907, "end_pos": 32268105, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000118378.1", "url": "https://www.ensembl.org/id/ENSBTAT00000118378.1" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000095903.1", "url": "https://www.ensembl.org/id/ENSBTAP00000095903.1" } ] } }, { "isoform_ac": "A0AAA9TV71-1", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TV71/entry", "sequence": { "sequence": "MAEESSEVPGELIESIKDVLGRKIKIALKKKVKLEVKGDKVENRVLVLTSCRAFLVTARIPTKLEVTFSYLEIHGVICSKPAQMVVETEKCSISMKMASPEDVSEVLAHIGTNLRKIFPGLSPVRIMKKVFMEPSERLASLQALWDSQTVTEQGPCGGFSQMYACVCDWLGFSYREEVQWDVDTIYLTQDTRELNLQDFSHLDHRDLIPIIAALEYNQWFTKLSSKDLKLSTDVCEQILRVVSRSNRLEELVLENAGLRIDFAQKLASALAHNPTSGLHTINLAGNPLEDRGVSSLSIQFAKLPKGLKHLNLSKTSLSPKGVNSLSQSLSANPLTATTLVHLDLSGNILRGDDLSSMYSFLAQPNAIAHLDLSNTECSLDMVCGALLRGCLQYLAVLNLSRTVFSHRKGKEVPPSFKQFFSSSLALMQINLSGTKLSPEPLKALLLGLASNHNLKGVSLDLSNCELRSGGAQVLEGCIAEIHNISSLDISDNGLESDLSTLIVWLSKNRSIQHLALGKNFNNMKSKNLTPVLDNLVQMIQDEESPLQSLSLADSKLKTGVTIIINALGSNTSLTKVDISGNGMGDMGAKMLAKALQINTKLRTVIWDKNNITAQGFQDIAVAMEKNYTLRFMPIPMYDASQALKTNPEKTEEALQKIENYLLRNHETRKYLQEQAYRLQQGIVTSTTQQMIDRMCVKVQDHLNSLRSCEGDAVQEDLKSAERLMQDAKNSKTLLPNLYHVGSVSWAGASGLLSSPIQETLESMAGEVTRVVDEQLKALLESMVDAAENLCPNVMRKAHIRQDLIHASTEKISIPRTFVKNVLLEQSGIDILNKISEVKLTVASFLSDRIVDEILDALSHCHHKLADHFSRRGKTLLQQDSLEMELAEEKPVKRSIITVEELTEIERLEDLDTCMMTPKSKRKTIHSRMLRPVSRAFEMEFDLDKALEEVPIHIEDPPFPSIRQEKRSSGFISDLPSEEGRKLEHFTKLRPKRAKKQQSTHPAGCATSIVSQDGEQNGLMGRVDEGVDEFFTKKVTKMDSKRWSARGSESHELSEGGDEKKKRDFRKTGFLNLIKPRNKPERSSTVLTAEELSSPKAGVRSPAVDAPRKDTKPAEHNGSADRVEEIKTPDSLEESQGEDVGKVDRSDSKGSPQGGRRYGVQMMGSGLLAEMKAKQEMKAKAACSLKKLGNDAVSQDSSSLTLSSTERLDGGGAVPKVHPENRFGLGTPEKNAKADLKAEAVSKPRSFSNRPTSPKPLLQAPKPNLAARPTIPQKPRTASRPEDVPDSPSSPGSPKVALLPPVLKKVPSDKERDGQGSPQPSPRTFSREVSRRSWSQQAQECQEQKQWASSKDGQPGSKSSDSGEEAEREYIFV", "length": 1372, "header": "tr|A0AAA9TV71-1|A0AAA9TV71_BOVIN Isoform 1 of Capping protein regulator and myosin 1 linker 1 OS=Bos taurus OX=9913 GN=CARMIL1 PE=1 SV=1 CANONICAL=A0AAA9TV71-1" }, "locus": { "chromosome": "23", "start_pos": 32573502, "end_pos": 32268105, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000098724.1", "url": "https://www.ensembl.org/id/ENSBTAT00000098724.1" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000101294.1", "url": "https://www.ensembl.org/id/ENSBTAP00000101294.1" } ] } }, { "isoform_ac": "F1MMJ6-1", "url": "https://www.uniprot.org/uniprotkb/F1MMJ6/entry", "sequence": { "sequence": "MAEESSEVPGELIESIKDVLGRKIKIALKKKVKLEVKGDKVENRVLVLTSCRAFLVTARIPTKLEVTFSYLEIHGVICSKPAQMVVETEKCSISMKMASPEDVSEVLAHIGTNLRKIFPGLSPVRIMKKVFMEPSERLASLQALWDSQTVTEQGPCGGFSQMYACVCDWLGFSYREEVQWDVDTIYLTQDTRELNLQDFSHLDHRDLIPIIAALEYNQWFTKLSSKDLKLSTDVCEQILRVVSRSNRLEELVLENAGLRIDFAQKLASALAHNPTSGLHTINLAGNPLEDRGVSSLSIQFAKLPKGLKHLNLSKTSLSPKGVNSLSQSLSANPLTATTLVHLDLSGNILRGDDLSSMYSFLAQPNAIAHLDLSNTECSLDMVCGALLRGCLQYLAVLNLSRTVFSHRKGKEVPPSFKQFFSSSLALMQINLSGTKLSPEPLKALLLGLASNHNLKGVSLDLSNCELRSGGAQVLEGCIAEIHNISSLDISDNGLESDLSTLIVWLSKNRSIQHLALGKNFNNMKSKNLTPVLDNLVQMIQDEESPLQSLSLADSKLKTGVTIIINALGSNTSLTKVDISGNGMGDMGAKMLAKALQINTKLRTVIWDKNNITAQGFQDIAVAMEKNYTLRFMPIPMYDASQALKTNPEKTEEALQKIENYLLRNHETRKYLQEQAYRLQQGIVTSTTQQMIDRMCVKVQDHLNSLRSCEGDAVQEDLKSAERLMQDAKNSKTLLPNLYHVGSVSWAGASGLLSSPIQETLESMAGEVTRVVDEQLKALLESMVDAAENLCPNVMRKAHIRQDLIHASTEKISIPRTFVKNVLLEQSGIDILNKISEVKLTVASFLSDRIVDEILDALSHCHHKLADHFSRRGKTLLQQDSLEMELAEEKPVKRSIITVEELTEIERLEDLDTCMMTPKSKRKTIHSRMLRPVSRAFEMEFDLDKALEEVPIHIEDPPFPSIRQEKRSSGFISDLPSEEGRKLEHFTKLRPKRAKKQQSTHPAGCATSIVSQDGEQNGLMGRVDEGVDEFFTKKVTKMDSKRWSARGSESHELSEGGDEKKKRDFRKTGFLNLIKPRNKPERSSTVLTAEELSSPKAGVRSPAVDAPRKDTKPAEHNGSADRVEEIKTPDSLEESQGEDVGKVDRSDSKGSPQGGRRYGVQMMGSGLLAEMKAKQEMKAKAACSLKCLKCIQRTASVWEPQKRMPKPTSRRRRSPSPGAFPTGPPARSPSCRPPNPTWRHGPPFRRNQELPRGLRTSQTLHPVRVLLKSLFFLPS", "length": 1274, "header": "tr|F1MMJ6-1|A0AAA9TV71_BOVIN Computationally mapped isoform of Capping protein regulator and myosin 1 linker 1 OS=Bos taurus OX=9913 GN=CARMIL1 PE=1 SV=3 CANONICAL=A0AAA9TV71-1" }, "locus": { "chromosome": "23", "start_pos": 32573502, "end_pos": 32276532, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000022015.8", "url": "https://www.ensembl.org/id/ENSBTAT00000022015.8" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000022015.6", "url": "https://www.ensembl.org/id/ENSBTAP00000022015.6" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [ { "id": "bta:537314", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?bta:537314", "resource": "KEGG Pathway" } ], "orthologs": [ { "uniprot_canonical_ac": "A0A0B4KEE7-1", "protein_name": "Leucine-rich repeat, isoform F", "gene_name": "LRR", "tax_id": 7227, "organism": "Drosophila melanogaster", "sequence": { "sequence": "MSTRSQLTKDLNESVKSILGRHTKILVKYMVKLETKGDKTENRVLVFTPVRVYLLSAKVPTKIECHFHYLDIVGVESKKSTHFSIVTNDRPYSFVTTGDAGNFSSVRHNHLLNADVILTDLASAIKQIFPTVPLKYIIRKIDIQPPERETIFSEEFRPSDPRNVGPCGGFSAQYACMCDFHGVPYREEVAWDVDTIYLSHDTRVLNLRDFDHLEPKDLMAIVSALEYNTFFRGLKAAHMRLSHETLERILHVLKRSMWLEELHLEALGLRWDFLNKLSISVITNSNPAIRTIDLSHNIIEDKGASSLCALFGKIVQGAIHLAGPIAKVSKGLCKLALAHCGLTSKGVNQMSHSLTLNQSISNSLTYLDLSGNSLKDDITNLHNFLAQPNVLEHLDLASTDITLENLFGALLRGCATHLAHLNVSHNSFSTKKGKEIPPSFKQFFTSTFSLKHLNIAGCKLPMEALKNLLLGLACNESTAGLYLDLSSNTLGAQGAHVLESCIHGVRVLQSLDISDNNLDAELAPVLTAISKNPSIRTLHLTRSLTGMKPKHIPPVMDALVNLIQKDDFPLVELVLSENKLKHDLHDFINALGSNQSLQKLDISGNFMGDVGARLLAKALQINNRLRTIYMDKNGVTLQGYADIVYALEHNHSMRTIPFPVFDIAPHLKSHPDKTDAVMRKMQELLQRNCNGLKRATGQGFRLQHGFMLSSTHQLVDKLVAETQDTISLAKGGSESASAVQRLITDAENCKQLMPKLQEAVRNESHPIEMKMTRVASELSYTIKSYLEETMETMMRTGIEQCPKTLGNQIVVQDLRKALAERLVVPEEFLQICLLNNAGSEIMNKVGEIEQSLAAAISDRATDEVLEALTRYRRGMGIAESPSVLLDEPQTPDIVRSRSSHDADGLIIRPGGRGSILPKLGLESPTKLEYLNLATPHLPTKRRSLAKKVRPQSVVENLSLGHFPDLLESPSSHRSNSQLSARAAAGAAALVGAANMTDSIAVDDGGVDECCDSITELPSASFQLQHLVKGRPKRAKTRAPTRPLVTTECAGGSREIGEGLEHFFRPGSVTPTTLTPLVSPTSEECSSLSFVDSPTMSRDGNGHMTSEETTPILEERRPIKLERQSPLLKSASWATRSRSTDNLEKYSPLVGRKSPLVKMRTEGGPGSGSATGAEETSMPSSNLLKATAREDKTRSPSSDSIKSHAAGEGSVIVKTGNGILRTPIVLQKPRPWSVVGSEPKAGGDLITGNGNADSSKTTPDKLEEDDVEIVTFGNTCSGSIVGITPGIALSTSGGGSIVGITPGGALEKKSVRELAAGLNRMELPLKPPVMPRTLLNATSVRTSTSSTGSTSNSVSVSSSTNANTSMTVLNQSQTRSRIVSSTSSTDSTETITERSTTSTSSSSSSSYEKQHAKACANLISNEILSMRNGQLGAKSGSCAESGGVKRIAGKEISTLFEETLVEELQQSMATRRGFRDSTYTKEDVVDL", "length": 1486 }, "evidence": [ { "id": "A0AAA9TV71", "url": "https://omabrowser.org/oma/group/A0AAA9TV71/", "database": "OMA" } ], "glygen_name": "Fruit fly", "common_name": "Fruit fly" }, { "uniprot_canonical_ac": "A0A8I6A2B1-1", "protein_name": "Capping protein regulator and myosin 1 linker 1", "gene_name": "Carmil1", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MTDESSDVPRELMESIKDVIGRKIKISVKKKVKLEVKGDRVENKVLVLTSCRAFLLSARIPTKLELTFSYLEIHGVICHKPTQMVVETEKCNVSMKMASLEDASDVLAHIGTCLRRIFPGLSPLRIMKKVSMEPSERLASLQALWDSQTLAEPGPCGGFSQMYACVCDWLGFSYREEVQWDVDTIYLTQDTRELNLQDFSHLEHRDLIPIIAALEYNQWFTKLSSKDLKLSTDVCEQILRVVSRSNLLEELVLENAGLRTDFAQKLASALAHNPNSGLHTINLAGNPLEDRGVSSLSIQFAKLPKGLKHLNLSKTSLSPKGVNSLCQSLSANPLTASTLTHLDLSGNVLRGDDLSHMYNFLAQPNTIVHLDLSNTECSLEMVCSALLRGCLQCLAVLNLSRSVFSHRKGKEVPPSFKQFFSSSLALIQINLSGTKLSPEPLKALLLGLACNHSLKGVSLDLSNCELRSGGAQVLEGCIAEIHNITSLDISDNGLESDLSTLIVWLSRNRSIQHLALGKNFNNMKSKNLTPVLDNLVQMIQDEDSPLQSLSLADSKLKTEVTIIINALGSNTSLTKVDISGNSMGDMGAKMLAKALQINTKLRTVIWDKNNITAQGFQDIAVAMEKNYTLRFMPIPMYDASQALKTSPEKTEEALQKIENYLLRNHETRKYLQEQAYRLQQGIVTSTTQQMIDRICVKVQDHLNSLRACGGDAIQEDLKAAERLMRDAKNSKTLLPNLYHVGGASWAGASGLSSSPIQEILESMAGEVTRVVDEQLKGLLESMVDAAENLCPNVMRKAHIRQDLIHASTEKISIPRTFVKNVLLEQSGIDILNKISEVKLTVASFLSDRIVDEILDSLSNSHRKLANHFSRLSKSLPQREDLEVELVEEKPVKRAILTVEDLTEVEKLEDLDTCMTLCCTSMTPKSKRKSIHSRMLRPVSRAFEMEFDLDKALEEVPIHIEDPPFPSVRQEKRSSGLISELPSEEGRRLEHFTKLRPKRNKKQQPTQAAVCSINIIPHDGEQNGLMGRVDEGVDEFFTKKVTKMDCKRSSTRCSDTHDLVEGDEKKKRDSRRSGFLNLIKSRSRSERPPTVLMTEELSSPKGAVRSPPVDTARKEIKAAEHNGAPERTEEMRTPEPLEEGLAEEAGRAERSDSRGSPQGGRRYVQVMGSGLLAEMKAKQERRAACAQKKLGNDVISQDPSSPVMSNTERLDGGATVPKLQPGLPEARFGLGTPEKNAKAEPRVDGGCRSRNSSSMPTSPKPLLQSPKPSPAARPSIPQKPRTASKPEDTPDSPSGPSSPKVALLPPILKKVSLDKERDDQSSSQSSPRTFSQEVQRGDHFKRHSDHDKPSSRGKRSSKLCFAIAEEEVNAPGYRKSQPTNVSRRSWGPAQEYQEQKQRNLGKDGHQGSKSSDSGEEAEKEFIFV", "length": 1423 }, "evidence": [ { "id": "A0AAA9TV71", "url": "https://omabrowser.org/oma/group/A0AAA9TV71/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "Q5VZK9-1", "protein_name": "F-actin-uncapping protein LRRC16A", "gene_name": "CARMIL1", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MTEESSDVPRELIESIKDVIGRKIKISVKKKVKLEVKGDKVENKVLVLTSCRAFLVTARIPTKLELTFSYLEIHGVVCSKSAQMIVETEKCSISMKMASPEDVSEVLAHIGTCLRKIFPGLSPVRIMKKVSMEPSERLASLQALWDSQTVAEQGPCGGFSQMYACVCDWLGFSYREEVQWDVDTIYLTQDTRELNLQDFSHLDHRDLIPIIAALEYNQWFTKLSSKDLKLSTDVCEQILRVVSRSNRLEELVLENAGLRTDFAQKLASALAHNPNSGLHTINLAGNPLEDRGVSSLSIQFAKLPKGLKHLNLSKTSLSPKGVNSLSQSLSANPLTASTLVHLDLSGNVLRGDDLSHMYNFLAQPNAIVHLDLSNTECSLDMVCGALLRGCLQYLAVLNLSRTVFSHRKGKEVPPSFKQFFSSSLALMHINLSGTKLSPEPLKALLLGLACNHNLKGVSLDLSNCELRSGGAQVLEGCIAEIHNITSLDISDNGLESDLSTLIVWLSKNRSIQHLALGKNFNNMKSKNLTPVLDNLVQMIQDEESPLQSLSLADSKLKTEVTIIINALGSNTSLTKVDISGNGMGDMGAKMLAKALQINTKLRTVIWDKNNITAQGFQDIAVAMEKNYTLRFMPIPMYDASQALKTNPEKTEDALQKIENYLLRNHETRKYLQEQAYRLQQGIVTSTTQQMIDRICVKVQDHLNSLRNCGGDAIQEDLKSAERLMRDAKNSKTLLPNLYHVGGASWAGASGLLSSPIQETLESMAGEVTRVVDEQLKALLESMVDAAENLCPNVMKKAHIRQDLIHASTEKISIPRTFVKNVLLEQSGIDILNKISEVKLTVASFLSDRIVDEILDALSHCHHKLADHFSRRGKTLPQQESLEIELAEEKPVKRSIITVEELTEIERLEDLDTCMMTPKSKRKSIHSRMLRPVSRAFEMEFDLDKALEEVPIHIEDPPFPSLRQEKRSSGFISELPSEEGKKLEHFTKLRPKRNKKQQPTQAAVCAANIVSQDGEQNGLMGRVDEGVDEFFTKKVTKMDSKKWSTRGSESHELNEGGDEKKKRDSRKSSGFLNLIKSRSKSERPPTILMTEEPSSPKGAVRSPPVDCPRKDTKAAEHNGNSERIEEIKTPDSFEESQGEEIGKVERSDSKSSPQAGRRYGVQVMGSGLLAEMKAKQEKRAACAQKKLGNDAVSQDSSSPALSGVERSDGGGAVPKLHPGLPENRFGLGTPEKNTKAEPKAEAGSRSRSSSSTPTSPKPLLQSPKPSLAARPVIPQKPRTASRPDDIPDSPSSPKVALLPPVLKKVPSDKERDGQSSPQPSPRTFSQEVSRRSWGQQAQEYQEQKQRSSSKDGHQGSKSNDSGEEAEKEFIFV", "length": 1371 }, "evidence": [ { "id": "A0AAA9TV71", "url": "https://omabrowser.org/oma/group/A0AAA9TV71/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "Q6EDY6-1", "protein_name": "F-actin-uncapping protein LRRC16A", "gene_name": "Carmil1", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MTDESSDVPRELMESIKDVIGRKIKISVKKKVKLEVKGDRVENKVLVLTSCRAFLLSARIPSKLELTFSYLEIHGVICHKPAQMVVETEKCNMSMKMVSPEDVSEVLAHIGTCLRRIFPGLSPLRIMKKVSMEPSERLASLQALWDSQTLAEPGPCGGFSQMYACVCDWLGFSYKEEVQWDVDTIYLTQDTRELNLQDFSHLEHRDLIPIIAALEYNQWFTKLSSKDLKLSTDVCEQILRVVSRSNRLEELVLENAGLRIDFAQKLAGALAHNPNSGLHTINLAGNSLEDRGVSSLSIQFAKLPKGLKHLNLSKTSLSPKGVNSLCQSLSANPLTASTLTHLDLSGNALRGDDLSHMYNFLAQPNTIVHLDLSNTECSLEMVCSALLRGCLQCLAVLNLSRSVFSHRKGKEVPPSFKQFFSSSLALIQINLSGTKLSPEPLKALLLGLACNHSLKGVSLDLSNCELGHCLRSGGAQVLEGCIAEIHNITSLDISDNGLESDLSTLIVWLSKNRSIQHLALGKNFNNMKSKNLTPVLDNLVQMIQDEDSPLQSLSLADSKLKAEVTIIINALGSNTSLTKVDISGNGMGDMGAKMLAKALQINTKLRTVIWDKNNITAQGFQDIAVAMEKNYTLRFMPIPMYDAAQALKTNPEKTEEALQKIENYLLRNHETRKYLQEQAYRLQQGIVTSTTQQMIDRICVKVQDHLNSLRACGGDAIQEDLKAAERLMRDAKNSKTLLPNLYHVGGASWAGASGLSSSPIQETLESMAGEVTRVVDEQLKDLLESMVDAAETLCPNVMRKAHIRQDLIHASTEKISIPRTFVKNVLLEQSGIDILNKISEVKLTVASFLSDRIVDEILDSLSSSHRKLANHFSRLNKSLPQREDLEVELVEEKPVKRAILTVEDLTEVERLEDLDTCMMTPKSKRKSIHSRMLRPVSRAFEMEFDLDKALEEVPIHIEDPPFPSVRQEKRSSGLISELPSEEGRRLEHFTKLRPKRNKKQQPTQAAVCTISILPQDGEQNGLMGRVDEGVDEFFTKKVTKMDCKRSSSRSSDAHELGEGDEKKKRDSRRSGFLNLIKSRSRSERPPTVLMTEELSSPKGAMRSPPVDTTRKEIKAAEHNGAPDRTEEIKTPEPLEEGPAEEAGRAERSDSRGSPQGGRRYVQVMGSGLLAEMKAKQERRAACAQKKLGNDVISQDPSSPVSCNTERLEGGATVPKLQPGLPEARFGSGTPEKNAKAEPRVDGGCRSRSSSSMPTSPKPLLQSPKPSPSARPSIPQKPRTASRPEDTPDSPSGPSSPKVALLPPILKKVSSDKERDGQNSSQSSPRSFSQEASRRSWGPAQEYQEQKQRSSGKDGHQGSKCSDSGEEAEKEFIFV", "length": 1374 }, "evidence": [ { "id": "A0AAA9TV71", "url": "https://omabrowser.org/oma/group/A0AAA9TV71/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" } ], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 6, "go_terms": [ { "name": "cytoplasm", "id": "GO:0005737", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005737", "evidence": [ { "database": "UniProtKB", "id": "A0AAA9TV71", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TV71" } ], "pmid": "" }, { "name": "plasma membrane", "id": "GO:0005886", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005886", "evidence": [ { "database": "UniProtKB", "id": "A0AAA9TV71", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TV71" } ], "pmid": "" }, { "name": "cytosol", "id": "GO:0005829", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005829", "evidence": [ { "database": "UniProtKB", "id": "A0AAA9TV71", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TV71" } ], "pmid": "" }, { "name": "lamellipodium", "id": "GO:0030027", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030027", "evidence": [ { "database": "UniProtKB", "id": "A0AAA9TV71", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TV71" } ], "pmid": "" }, { "name": "macropinosome", "id": "GO:0044354", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0044354", "evidence": [ { "database": "UniProtKB", "id": "A0AAA9TV71", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TV71" } ], "pmid": "" }, { "name": "filamentous actin", "id": "GO:0031941", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0031941", "evidence": [ { "database": "UniProtKB", "id": "A0AAA9TV71", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TV71" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 12, "go_terms": [ { "name": "cell migration", "id": "GO:0016477", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016477", "evidence": [ { "database": "UniProtKB", "id": "A0AAA9TV71", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TV71" } ], "pmid": "" }, { "name": "positive regulation of cell migration", "id": "GO:0030335", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030335", "evidence": [ { "database": "UniProtKB", "id": "A0AAA9TV71", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TV71" } ], "pmid": "" }, { "name": "urate metabolic process", "id": "GO:0046415", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0046415", "evidence": [ { "database": "UniProtKB", "id": "A0AAA9TV71", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TV71" } ], "pmid": "" }, { "name": "positive regulation of stress fiber assembly", "id": "GO:0051496", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0051496", "evidence": [ { "database": "UniProtKB", "id": "A0AAA9TV71", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TV71" } ], "pmid": "" }, { "name": "lamellipodium assembly", "id": "GO:0030032", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030032", "evidence": [ { "database": "UniProtKB", "id": "A0AAA9TV71", "url": 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repair protein ERCC-1 OS=Bos taurus OX=9913 GN=ERCC1 PE=3 SV=1 CANONICAL=A0AAA9TUH4-1" }, "isoforms": [ { "isoform_ac": "A0AAA9RWS8-1", "url": "https://www.uniprot.org/uniprotkb/A0AAA9RWS8/entry", "sequence": { "sequence": "MDKECVSWTLLPPEILLFAAYPTTVPRGNLGRPSRRGARNGVGSSPAPPLSPIRGPPLRAGPQKELAMDEEGVHKPAGPPTRKKFLIPTDEDVVPPPGAKPLFRSTRSLPTVETSPPPGPQTYAEYALSGPPGGAEATRPVGPEPLAEETPNQAPKPGAKSNSIIVSPRQRGNPVLRFVRNVPWEFGDVLPDYVLGQSTCALFLSLRYHNLHPDYIHQRLQSLGKSYALRVLLVQVDVKDPQQALKELAKMCILADCTLILAWSPEEAGRYLETYKAYEQKPADLLMEKLEQDFVSRVTECLTTVKSVNKTDSQTLLTTFGSLEQLIAASREDLSLCPGLGPQKARRLFDVFHEPFLKVPH", "length": 361, "header": "tr|A0AAA9RWS8-1|A0AAA9TUH4_BOVIN Computationally mapped isoform of DNA excision repair protein ERCC-1 OS=Bos taurus OX=9913 GN=ERCC1 PE=3 SV=1 CANONICAL=A0AAA9TUH4-1" }, "locus": { "chromosome": "18", "start_pos": 53073578, "end_pos": 53024594, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000124776.1", "url": 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"ENSBTAT00000100091.1", "url": "https://www.ensembl.org/id/ENSBTAT00000100091.1" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000093914.1", "url": "https://www.ensembl.org/id/ENSBTAP00000093914.1" } ] } }, { "isoform_ac": "A0AAA9TQY2-1", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TQY2/entry", "sequence": { "sequence": "KELAMDEEGVHKPAGPPTRKKFLIPTDEDVVPPPGRGNPVLRFVRNVPWEFGDVLPDYVLGQSTCALFLSLRYHNLHPDYIHQRLQSLGKSYALRVLLVQVDVKDPQQALKELAKMCILADCTLILAWSPEEAGRYLETYKAYEQKPADLLMEKLEQDFVSRVTECLTTVKSVNKTDSQTLLTTFGSLEQLIAASREDLSLCPGLGPQKARRLFDVFHEPFLKVPH", "length": 226, "header": "tr|A0AAA9TQY2-1|A0AAA9TUH4_BOVIN Computationally mapped isoform of DNA excision repair protein ERCC-1 OS=Bos taurus OX=9913 GN=ERCC1 PE=3 SV=1 CANONICAL=A0AAA9TUH4-1" }, "locus": { "chromosome": "18", "start_pos": 53038560, "end_pos": 53024594, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000092316.1", "url": "https://www.ensembl.org/id/ENSBTAT00000092316.1" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000100995.1", "url": "https://www.ensembl.org/id/ENSBTAP00000100995.1" } ] } }, { "isoform_ac": "A0AAA9TU03-1", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TU03/entry", "sequence": { "sequence": "KELAMDEEGVHKPAGPPTRKKFLIPTDEDVVPPPGAKPLFRSTRSLPTVETSPPPGPQTYAEYALSGPPGGAEATRPVGPEPLAEETPNQAPKPGAKSNSIIVSPRQRGNPVLRFVRNVPWEFGDVLPDYVLGQSTCALFLSLRYHNLHPDYIHQRLQSLGKSYALRVLLVQVDVKDPQQALKELAKMCILADCTLILAWRPEGCLMSSTSLS", "length": 213, "header": "tr|A0AAA9TU03-1|A0AAA9TU03_BOVIN Computationally mapped isoform of ERCC excision repair 1, endonuclease non-catalytic subunit OS=Bos taurus OX=9913 GN=ERCC1 PE=3 SV=1 CANONICAL=A0AAA9TUH4-1" }, "locus": { "chromosome": "18", "start_pos": 53038560, "end_pos": 53024608, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000090023.1", "url": "https://www.ensembl.org/id/ENSBTAT00000090023.1" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000100570.1", "url": "https://www.ensembl.org/id/ENSBTAP00000100570.1" } ] } }, { "isoform_ac": "A0AAA9TUH4-1", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TUH4/entry", "sequence": { "sequence": "MCGCRFYCGDCDLQEGRAELILLFAAYPTTVPRGNLGRPSRRGARNGVGSSPAPPLSPIRGPPLRAGPQKELAMDEEGVHKPAGPPTRKKFLIPTDEDVVPPPGAKPLFRSTRSLPTVETSPPPGPQTYAEYALSGPPGGAEATRPVGPEPLAEETPNQAPKPGAKSNSIIVSPRQRGNPVLRFVRNVPWEFGDVLPDYVLGQSTCALFLSLRYHNLHPDYIHQRLQSLGKSYALRVLLVQVDVKDPQQALKELAKMCILADCTLILAWSPEEAGRYLETYKAYEQKPADLLMEKLEQDFVSRVTECLTTVKSVNKTDSQTLLTTFGSLEQLIAASREDLSLCPGLGPQKARRLFDVFHEPFLKVPH", "length": 367, "header": "tr|A0AAA9TUH4-1|A0AAA9TUH4_BOVIN Isoform 1 of DNA excision repair protein ERCC-1 OS=Bos taurus OX=9913 GN=ERCC1 PE=3 SV=1 CANONICAL=A0AAA9TUH4-1" }, "locus": { "chromosome": "18", "start_pos": 53069977, "end_pos": 53024594, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000127546.1", "url": "https://www.ensembl.org/id/ENSBTAT00000127546.1" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000100214.1", "url": "https://www.ensembl.org/id/ENSBTAP00000100214.1" } ] } }, { "isoform_ac": "A0AAF6Z4C8-1", "url": "https://www.uniprot.org/uniprotkb/A0AAF6Z4C8/entry", "sequence": { "sequence": "KELAMDEEGVHKPAGPPTRKKFLIPTDEDVVPPPGAKPLFRSTRSLPTVETSPPPGPQTYAEYALSGPPGGAEATRPVGPEPLAEETPNQAPKPGAKSNSIIVSPRQRGNPVLRFVRNVPWEFGDVLPDYVLGQSTCALFLSLRYHNLHPDYIHQRLQSLGKSYALRVLLVQVDVKDPQQALKELAKMCILADCTLILAWSPEEAGRYLETYKAYEQKPADLLMEKLEQDFVSRVTECLTTVKSVNKTDSQTLLTTFGSLEQLIAASREDLSLCPGLGPQKARRLFDVFHEPFLKVPH", "length": 298, "header": "tr|A0AAF6Z4C8-1|A0AAF6Z4C8_BOVIN Computationally mapped isoform of DNA excision repair protein ERCC-1 OS=Bos taurus OX=9913 GN=ERCC1 PE=3 SV=1 CANONICAL=A0AAA9TUH4-1" }, "locus": { "chromosome": "18", "start_pos": 53038560, "end_pos": 53024594, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000023078.6", "url": "https://www.ensembl.org/id/ENSBTAT00000023078.6" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000023078.5", "url": "https://www.ensembl.org/id/ENSBTAP00000023078.5" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [], "orthologs": [], "go_annotation": { "categories": [ { "name": "Biological Process", "total": 11, "go_terms": [ { "name": "regulation of telomere maintenance", "id": "GO:0032204", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0032204", "evidence": [ { "database": "UniProtKB", "id": "A0AAA9TUH4", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TUH4" } ], "pmid": "" }, { "name": "DNA recombination", "id": "GO:0006310", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006310", "evidence": [ { "database": "UniProtKB", "id": "A0AAA9TUH4", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TUH4" } ], "pmid": "" }, { "name": "telomere maintenance", "id": "GO:0000723", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000723", "evidence": [ { "database": "UniProtKB", "id": "A0AAA9TUH4", "url": 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"UniProtKB", "id": "A0AAA9TUH4", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TUH4" } ], "pmid": "" }, { "name": "negative regulation of protection from non-homologous end joining at telomere", "id": "GO:1905765", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:1905765", "evidence": [ { "database": "UniProtKB", "id": "A0AAA9TUH4", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TUH4" } ], "pmid": "" }, { "name": "response to oxidative stress", "id": "GO:0006979", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006979", "evidence": [ { "database": "UniProtKB", "id": "A0AAA9TUH4", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TUH4" } ], "pmid": "" }, { "name": "double-strand break repair via nonhomologous end joining", "id": "GO:0006303", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006303", "evidence": [ { "database": "UniProtKB", "id": "A0AAA9TUH4", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TUH4" } ], "pmid": "" }, { "name": "t-circle formation", "id": "GO:0090656", "url": 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"count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ], "tool_support": { "graph_view": "yes" } }, { "uniprot_canonical_ac": "A0AAA9TUU3-1", "uniprot_ac": "A0AAA9TUU3", "uniprot_id": "A0AAA9TUU3_BOVIN", "mass": { "chemical_mass": 27252.0, "monoisotopic_mass": 27252.0 }, "refseq": {}, "gene_names": [ { "name": "CHMP6", "type": "recommended", "evidence": [ { "id": "A0AAA9TUU3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TUU3" } ] } ], "protein_names": [ { "name": "Charged multivesicular body protein 6", "type": "synonym", "evidence": [ { "id": "A0AAA9TUU3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TUU3/entry#names_and_taxonomy" } ] } ], "function": [], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Bos taurus", "taxid": 9913, "evidence": [ { "database": "UniProtKB", "id": "A0AAA9TUU3", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TUU3" } ], "common_name": "Bovine", "glygen_name": "Bovine", "reference_species": "Bos taurus [9913]" } ], "gene": [ { "name": "CHMP6", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TUU3", "locus": { "chromosome": "19", "start_pos": 51644407, "end_pos": 51677262, "strand": "+", "evidence": [ { "database": "Ensembl Gene", "id": "ENSBTAG00000038745", "url": "https://www.ensembl.org/id/ENSBTAG00000038745" } ] } } ], "crossref": [ { "id": "A0AAA9TUU3", "url": "https://alphafold.ebi.ac.uk/entry/A0AAA9TUU3", "database": "AlphaFoldDB", "categories": [] }, { "id": "IPR005024", "url": "https://www.ebi.ac.uk/interpro/entry/IPR005024", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "PTHR22761", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR22761", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR22761:SF5", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR22761:SF5", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF03357", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF03357", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "A0AAA9RX13", "url": "https://www.uniprot.org/uniprotkb/A0AAA9RX13", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0AAA9RX13-1", "url": "https://www.uniprot.org/uniprotkb/A0AAA9RX13-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0AAA9RZR3", "url": "https://www.uniprot.org/uniprotkb/A0AAA9RZR3", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0AAA9RZR3-1", "url": "https://www.uniprot.org/uniprotkb/A0AAA9RZR3-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0AAA9S4M4", "url": "https://www.uniprot.org/uniprotkb/A0AAA9S4M4", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0AAA9S4M4-1", "url": "https://www.uniprot.org/uniprotkb/A0AAA9S4M4-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0AAA9SIW3", "url": 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"database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0AAA9TUU3", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TUU3", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0AAA9TUU3-1", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TUU3-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "F6R1M0", "url": "https://www.uniprot.org/uniprotkb/F6R1M0", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "F6R1M0-1", "url": "https://www.uniprot.org/uniprotkb/F6R1M0-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MGNLFGRKKQSRVTEQDKAILQLKQQRDKLKQYQKRITQQLEREREIARQLLRDGRKERAKLLLKKKRYREQLLDKTENQITSLETMVQSIEFTQIEMKVIEGLKIGNECLNKMHQVMSIEEVERILDETQEAVDYQRQIDELLAGSFTQEDEDAILEELDAITQEQIELPAVPSEPLPEKIPGHGQARRSWCWSHRPTRIVRLHEPVSPQRCLPFKAPQTPPHPSPSSCCSH", "length": 233, "header": "tr|A0AAA9TUU3-1|A0AAA9TUU3_BOVIN Isoform 1 of Charged multivesicular body protein 6 OS=Bos taurus OX=9913 GN=CHMP6 PE=3 SV=1 CANONICAL=A0AAA9TUU3-1" }, "isoforms": [ { "isoform_ac": "A0AAA9RX13-1", "url": "https://www.uniprot.org/uniprotkb/A0AAA9RX13/entry", "sequence": { "sequence": "MGNLFGRKKQSRVTEQDKAILQLKQQRDKLKQYQKRITQQLEREREIARQLLRDGRKERAKLLLKKKRYREQLLDKTENQITSLETMVQSIEFTQIEMKVIEGLKIGNECLNKMHQVMSIEEVERILDETQEAVDYQRQIDELLAGSFTQEDEDAILEELDAITQEQIELPAVPSEPLPEKIPARRTQGGL", "length": 191, "header": "tr|A0AAA9RX13-1|A0AAA9TUU3_BOVIN Computationally mapped isoform of Charged multivesicular body protein 6 OS=Bos taurus OX=9913 GN=CHMP6 PE=3 SV=1 CANONICAL=A0AAA9TUU3-1" }, "locus": { "chromosome": "19", "start_pos": 51676788, "end_pos": 51668590, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000121573.1", "url": "https://www.ensembl.org/id/ENSBTAT00000121573.1" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000077023.1", "url": "https://www.ensembl.org/id/ENSBTAP00000077023.1" } ] } }, { "isoform_ac": "A0AAA9RZR3-1", "url": "https://www.uniprot.org/uniprotkb/A0AAA9RZR3/entry", "sequence": { "sequence": "MGNLFGRKKQSRVTEQDKAILQLKQQRDKLKQYQKRITQQLEREREIARQLLRDGRKERAKLLLKKKRYREQLLDKTENQITSLETMVQSIEFTQIEMKVIEGLKIGNECLNKMHQVMSIEEVERILDETQEAVDYQRQIDELLAGSFTQEDEDAILEELDAITQEQIELPAVPSEPLPEKIPEEARSQMTQQETPPRLPSLLMLSHWGWGSRSAGRAGPGPGWSWPV", "length": 228, "header": "tr|A0AAA9RZR3-1|A0AAA9TUU3_BOVIN Computationally mapped isoform of Charged multivesicular body protein 6 OS=Bos taurus OX=9913 GN=CHMP6 PE=3 SV=1 CANONICAL=A0AAA9TUU3-1" }, "locus": { "chromosome": "19", "start_pos": 51676788, "end_pos": 51667460, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000135526.1", "url": "https://www.ensembl.org/id/ENSBTAT00000135526.1" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000076575.1", "url": "https://www.ensembl.org/id/ENSBTAP00000076575.1" } ] } }, { "isoform_ac": "A0AAA9S4M4-1", "url": "https://www.uniprot.org/uniprotkb/A0AAA9S4M4/entry", "sequence": { "sequence": "MGNLFGRKKQSRVTEQDKAILQLKQQRDKLKQYQKRITQQLEREREIARQLLRDGRKERAKLLLKKKRYREQLLDKTENQITSLETMVQSIEFTQIEMKVIEGLKIGNECLNKMHQVMSIEEVERILDETQEAVDYQRQIDELLAGSFTQEDEDAILEELDAITQTAGICSKPKPLLPVAWLATGRDWPGKNVLQVAHQLWQV", "length": 203, "header": "tr|A0AAA9S4M4-1|A0AAA9TUU3_BOVIN Computationally mapped isoform of Charged multivesicular body protein 6 OS=Bos taurus OX=9913 GN=CHMP6 PE=3 SV=1 CANONICAL=A0AAA9TUU3-1" }, "locus": { "chromosome": "19", "start_pos": 51676788, "end_pos": 51671856, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000107847.1", "url": "https://www.ensembl.org/id/ENSBTAT00000107847.1" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000078200.1", "url": "https://www.ensembl.org/id/ENSBTAP00000078200.1" } ] } }, { "isoform_ac": "A0AAA9SIW3-1", "url": "https://www.uniprot.org/uniprotkb/A0AAA9SIW3/entry", "sequence": { "sequence": "MELLVLKTKQQLKQQRDKLKQYQKRITQQLEREREIARQLLRDGRKERAKLLLKKKRYREQLLDKTENQITSLETMVQSIEFTQIEMKVIEGLKIGNECLNKMHQVMSIEEVERILDETQEAVDYQRQIDELLAGSFTQEDEDAILEELDAITQEQIELPAVPSEPLPEKIPEKVPVKARPRQAELVAAS", "length": 190, "header": "tr|A0AAA9SIW3-1|A0AAA9TUU3_BOVIN Computationally mapped isoform of Charged multivesicular body protein 6 OS=Bos taurus OX=9913 GN=CHMP6 PE=3 SV=1 CANONICAL=A0AAA9TUU3-1" }, "locus": { "chromosome": "19", "start_pos": 51677063, "end_pos": 51670379, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000096608.1", "url": "https://www.ensembl.org/id/ENSBTAT00000096608.1" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000082483.1", "url": "https://www.ensembl.org/id/ENSBTAP00000082483.1" } ] } }, { "isoform_ac": "A0AAA9SZF0-1", "url": "https://www.uniprot.org/uniprotkb/A0AAA9SZF0/entry", "sequence": { "sequence": "MGNLFGRKKQSRVTEQDKAILQLKQQRDKLKQYQKRITQQLEREREIARQLLRDGRKERAKLLLKKKRYREQLLDKTENQITSLETMVQSIEFTQIEMKVIEGLKIGNECLNKMHQVMSIEEVERILDETQEAVDYQRQIDELLAGSFTQEDEDAILEELDAITQEQIELPAVPSEPLPEKIPVPSQ", "length": 187, "header": "tr|A0AAA9SZF0-1|A0AAA9TUU3_BOVIN Computationally mapped isoform of Charged multivesicular body protein 6 OS=Bos taurus OX=9913 GN=CHMP6 PE=3 SV=1 CANONICAL=A0AAA9TUU3-1" }, "locus": { "chromosome": "19", "start_pos": 51676788, "end_pos": 51663086, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000097411.1", "url": "https://www.ensembl.org/id/ENSBTAT00000097411.1" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000090799.1", "url": "https://www.ensembl.org/id/ENSBTAP00000090799.1" } ] } }, { "isoform_ac": "A0AAA9TND5-1", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TND5/entry", "sequence": { "sequence": "MLNPKDVHTLDSLNSLLVTDPEDVIFRRRRATRLQQLKQQRDKLKQYQKRITQQLEREREIARQLLRDGRKERAKLLLKKKRYREQLLDKTENQITSLETMVQSIEFTQIEMKVIEGLKIGNECLNKMHQVMSIEEVERILDETQEAVDYQRQIDELLAGSFTQEDEDAILEELDAITQEQIELPAVPSEPLPEKIPEKVPVKARPRQAELVAAS", "length": 215, "header": "tr|A0AAA9TND5-1|A0AAA9TUU3_BOVIN Computationally mapped isoform of Charged multivesicular body protein 6 OS=Bos taurus OX=9913 GN=CHMP6 PE=3 SV=1 CANONICAL=A0AAA9TUU3-1" }, "locus": { "chromosome": "19", "start_pos": 51675108, "end_pos": 51670379, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000116455.1", "url": "https://www.ensembl.org/id/ENSBTAT00000116455.1" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000097860.1", "url": "https://www.ensembl.org/id/ENSBTAP00000097860.1" } ] } }, { "isoform_ac": "A0AAA9TQB2-1", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TQB2/entry", "sequence": { "sequence": "MGNLFGRKKQSRVTEQDKAILQLKQQRDKLKQYQKRITQQLEREREIARQLLRDGRKERAKLLLKKKRYREQLLDKTENQITSLETMVQSIEFTQIEMKVIEGLKIGNECLNKMHQVMSIEEVERILDETQEAVDYQRQIDELLAGSFTQEDEDAILEELDAITQEQIELPAVPSEPLPEKIPGAQ", "length": 186, "header": "tr|A0AAA9TQB2-1|A0AAA9TUU3_BOVIN Computationally mapped isoform of Charged multivesicular body protein 6 OS=Bos taurus OX=9913 GN=CHMP6 PE=3 SV=1 CANONICAL=A0AAA9TUU3-1" }, "locus": { "chromosome": "19", "start_pos": 51676788, "end_pos": 51644527, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000125156.1", "url": "https://www.ensembl.org/id/ENSBTAT00000125156.1" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000100770.1", "url": "https://www.ensembl.org/id/ENSBTAP00000100770.1" } ] } }, { "isoform_ac": "A0AAA9TUU3-1", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TUU3/entry", "sequence": { "sequence": "MGNLFGRKKQSRVTEQDKAILQLKQQRDKLKQYQKRITQQLEREREIARQLLRDGRKERAKLLLKKKRYREQLLDKTENQITSLETMVQSIEFTQIEMKVIEGLKIGNECLNKMHQVMSIEEVERILDETQEAVDYQRQIDELLAGSFTQEDEDAILEELDAITQEQIELPAVPSEPLPEKIPGHGQARRSWCWSHRPTRIVRLHEPVSPQRCLPFKAPQTPPHPSPSSCCSH", "length": 233, "header": "tr|A0AAA9TUU3-1|A0AAA9TUU3_BOVIN Isoform 1 of Charged multivesicular body protein 6 OS=Bos taurus OX=9913 GN=CHMP6 PE=3 SV=1 CANONICAL=A0AAA9TUU3-1" }, "locus": { "chromosome": "19", "start_pos": 51676788, "end_pos": 51669955, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000133541.1", "url": "https://www.ensembl.org/id/ENSBTAT00000133541.1" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000102395.1", "url": "https://www.ensembl.org/id/ENSBTAP00000102395.1" } ] } }, { "isoform_ac": "F6R1M0-1", "url": "https://www.uniprot.org/uniprotkb/F6R1M0/entry", "sequence": { "sequence": "MADIPRQLKQQRDKLKQYQKRITQQLEREREIARQLLRDGRKERAKLLLKKKRYREQLLDKTENQITSLETMVQSIEFTQIEMKVIEGLKIGNECLNKMHQVMSIEEVERILDETQEAVDYQRQIDELLAGSFTQEDEDAILEELDAITQEQIELPAVPSEPLPEKIPEKVPVKARPRQAELVAAS", "length": 186, "header": "tr|F6R1M0-1|F6R1M0_BOVIN Computationally mapped isoform of Charged multivesicular body protein 6 OS=Bos taurus OX=9913 GN=CHMP6 PE=3 SV=1 CANONICAL=A0AAA9TUU3-1" }, "locus": { "chromosome": "19", "start_pos": 51674795, "end_pos": 51670379, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000018623.5", "url": "https://www.ensembl.org/id/ENSBTAT00000018623.5" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000018623.4", "url": "https://www.ensembl.org/id/ENSBTAP00000018623.4" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [], "orthologs": [], "go_annotation": { "categories": [ { "name": "Biological Process", "total": 14, "go_terms": [ { "name": "vacuolar transport", "id": "GO:0007034", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007034", "evidence": [ { "database": "UniProtKB", "id": "A0AAA9TUU3", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TUU3" } ], "pmid": "" }, { "name": "protein transport", "id": "GO:0015031", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0015031", "evidence": [ { "database": "UniProtKB", "id": "A0AAA9TUU3", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TUU3" } ], "pmid": "" }, { "name": "plasma membrane repair", "id": "GO:0001778", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0001778", "evidence": [ { "database": "UniProtKB", "id": "A0AAA9TUU3", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TUU3" } ], "pmid": "" }, { "name": "nuclear membrane reassembly", "id": "GO:0031468", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0031468", "evidence": [ { "database": "UniProtKB", "id": "A0AAA9TUU3", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TUU3" } ], "pmid": "" }, { "name": "viral budding via host ESCRT complex", 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"database": "Ensembl Transcript", "id": "ENSBTAT00000101436.1", "url": "https://www.ensembl.org/id/ENSBTAT00000101436.1" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000092707.1", "url": "https://www.ensembl.org/id/ENSBTAP00000092707.1" } ] } }, { "isoform_ac": "A0AAA9TU60-1", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TU60/entry", "sequence": { "sequence": "MAKSPENSTLEEILGQYQRSLRERANRSIHQLKCALREGDVTVGEDMLDPSFNTSVGNEDAGNAWRELQHSHAVNQLKALLRQQAAKESEVSLRRQETSPSRSSECEETSMPTVHNLVPIINDQSQYIYHLEAEVKFCKEELSGMKNRVQVVVLENERLQQELKSRGQEEMREQTLLDASGNMQNSWIITGEDSRVDEAAKRSFSCGNASTIKVASAGEAEKWKLELERLKLTYEEKSEILESQLTFLRKDLAEYQKNCEDLKERLKHKESLLAANISNRVGGLCLKCAQHEAVLSQTHNNVHIQTIERLTKERDDLMSVLVSVRNSLTEVQQREASAYKQVKQAVKMTEDASFEKTKALIQCEQLKNELERQTDRLEKELASQQEKRAFEKEMLKKEITKEREDMGSKMLTLSQNIAQLEAEVEKVTREKISAVHQLEEIQNQLASREMDVTKVCEEMRYQLNKTKMEKDEAEKEHREYRTKTKRDLEIKDQEIEKLSLELSESKQRLEQQQEKATRAREECLKLTELLGESEHQLHLTRLEKDSIQQSFSNEAKAQALQAQQREQELTQKIQQMEAQHDKTENEQYSLLTSQNSFLTKLKEECCLLAKKLEQISQKSRSEIAQLSQEKRYTYDKLEKLQRRNDELEEQCVQHGRLHEIMKQRLKQLDKHSHATAQQLVQLLNKQNQLLLERQSLSEEVGHLRSQKVPGEAQVGQRSCGAAAMERCALLLPSSSDVPSYPACHNLIADLDETE", "length": 754, "header": "tr|A0AAA9TU60-1|A0AAA9TU60_BOVIN Computationally mapped isoform of SHH signaling and ciliosis regulator SDCCAG8 OS=Bos taurus OX=9913 GN=SDCCAG8 PE=4 SV=1 CANONICAL=A0AAA9TVM1-1" }, "locus": { "chromosome": "16", "start_pos": 33884180, "end_pos": 33638855, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000090987.1", "url": "https://www.ensembl.org/id/ENSBTAT00000090987.1" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000100089.1", "url": "https://www.ensembl.org/id/ENSBTAP00000100089.1" } ] } }, { "isoform_ac": "A0AAA9TVM1-1", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TVM1/entry", "sequence": { "sequence": "MAKSPENSTLEEILGQYQRSLRERANRSIHQLKCALREGDVTVGEDMLDPSFNTSVGNEDAGNAWRELQHSHAVNQLKALLRQQAAKESEVSLRRQETSPSRSSECEETSMPTVHNLVPIINDQSQYIYHLEAEVKFCKEELSGMKNRVQVVVLENERLQQELKSRGQEEMREQTLLDASGNMQNSWIITGEDSRVDEAAKRSFSCGNASTIKVASAGEAEKWKLELERLKLTYEEKSEILESQLTFLRKDLAEYQKNCEDLKERLKHKESLLAANISNRVGGLCLKCAQHEAVLSQTHNNVHIQTIERLTKERDDLMSVLVSVRNSLTEVQQREASAYKQVKQAVKMTEDASFEKTKALIQCEQLKNELERQTDRLEKELASQQEKRAFEKEMLKKEITKEREDMGSKMLTLSQNIAQLEAEVEKVTREKISAVHQLEEIQNQLASREMDVTKVCEEMRYQLNKTKMEKDEAEKEHREYRTKTKRDLEIKDQEIEKLSLELSESKQRLEQQQEKATRAREECLKLTELLGESEHQLHLTRLEKDSIQQSFSNEAKAQALQAQQREQELTQKIQQMEAQHDKTENEQYSLLTSQNSFLTKLKEECCLLAKKLEQISQKSRSEIAQLSQEKRYTYDKLEKLQRRNDELEEQCVQHGRLHEIMKQRLKQLDKHSHATAQQLVQLLNKQNQLLLERQSLSEEVGHLRSQLPSMPQSDC", "length": 715, "header": "tr|A0AAA9TVM1-1|A0AAA9TVM1_BOVIN Isoform 1 of SHH signaling and ciliosis regulator SDCCAG8 OS=Bos taurus OX=9913 GN=SDCCAG8 PE=4 SV=1 CANONICAL=A0AAA9TVM1-1" }, "locus": { "chromosome": "16", "start_pos": 33884180, "end_pos": 33638874, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000121167.1", "url": "https://www.ensembl.org/id/ENSBTAT00000121167.1" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000101463.1", "url": "https://www.ensembl.org/id/ENSBTAP00000101463.1" } ] } }, { "isoform_ac": "E1BKZ3-1", "url": "https://www.uniprot.org/uniprotkb/E1BKZ3/entry", "sequence": { "sequence": "MAKSPENSTLEEILGQYQRSLRERANRSIHQLKCALREGDVTVGEDMLDPSFNTSVGNEDAGNAWRELQHSHAVNQLKALLRQQAAKESEVSLRRQETSPSRSSECEETSMPTVHNLVPIINDQSQYIYHLEAEVKFCKEELSGMKNRVQVVVLENERLQQELKSRGQEEMREQTLLDASGNMQNSWIITGEDSRVDEAAKRSFSCGNASTIKVASAGEAEKWKLELERLKLTYEEKSEILESQLTFLRKDLAEYQKNCEDLKERLKHKESLLAANISNRVGGLCLKCAQHEAVLSQTHNNVHIQTIERLTKERDDLMSVLVSVRNSLTEVQQREASAYKQVKQAVKMTEDASFEKTKALIQCEQLKNELERQTDRLEKELASQQEKRAFEKEMLKKEITKEREDMGSKMLTLSQNIAQLEAEVEKVTREKISAVHQLEEIQNQLASREMDVTKVCEEMRYQLNKTKMEKDEAEKEHREYRTKTKRDLEIKDQEIEKLSLELSESKQRLEQQQEKATRAREECLKLTELLGESEHQLHLTRLEKDSIQQSFSNEAKAQALQAQQREQELTQKIQQMEAQHDKTENEQYSLLTSQNSFLTKLKEECCLLAKKLEQISQKSRSEIAQLSQEKRYTYDKLEKLQRRNDELEEQCVQHGRLHEIMKQRTKDILP", "length": 670, "header": "tr|E1BKZ3-1|E1BKZ3_BOVIN Computationally mapped isoform of SHH signaling and ciliosis regulator SDCCAG8 OS=Bos taurus OX=9913 GN=SDCCAG8 PE=4 SV=4 CANONICAL=A0AAA9TVM1-1" }, "locus": { "chromosome": "16", "start_pos": 33884180, "end_pos": 33657184, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000023634.7", "url": "https://www.ensembl.org/id/ENSBTAT00000023634.7" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000023634.7", "url": "https://www.ensembl.org/id/ENSBTAP00000023634.7" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [ { "id": "R-BTA-2565942", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-BTA-2565942", "resource": "Reactome", "description": "Regulation of PLK1 Activity at G2/M Transition" }, { "id": "R-BTA-380259", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-BTA-380259", "resource": "Reactome", "description": "Loss of Nlp from mitotic centrosomes" }, { "id": "R-BTA-380270", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-BTA-380270", "resource": "Reactome", "description": "Recruitment of mitotic centrosome proteins and complexes" }, { "id": "R-BTA-380284", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-BTA-380284", "resource": "Reactome", "description": "Loss of proteins required for interphase microtubule organization from the centrosome" }, { "id": "R-BTA-380320", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-BTA-380320", "resource": "Reactome", "description": "Recruitment of NuMA to mitotic centrosomes" }, { "id": "R-BTA-5620912", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-BTA-5620912", "resource": "Reactome", "description": "Anchoring of the basal body to the plasma membrane" }, { "id": "R-BTA-8854518", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-BTA-8854518", "resource": "Reactome", "description": "AURKA Activation by TPX2" } ], "orthologs": [ { "uniprot_canonical_ac": "B8JK76-1", "protein_name": "Serologically defined colon cancer antigen 8 homolog", "gene_name": "Sdccag8", "tax_id": 7955, "organism": "Danio rerio", "sequence": { "sequence": "MKPSLESDEEEELGALQKTLRERANRSIQHLSSMLAGHSSDSETSEPNQQELLSSVQQNPCSPVQQSEAVSQLRSLLQMKTKDANIQSLSPSRRKLAAKRATDDGSSSQPGVHNLVPIINNQSEYIQHLEAEVKFCKEELLEMKQRVRVVIVENEKLHHELKAKTIEDTLKEYTFVDSTLNMEHTAENTLKERLGSVNQAEDHKWRKEMEQLKCLYQAQTETLEAQVVSLKKDLACIQKEYEESKERLRHKEAMAVAAGTGQRVSGLCLKCAQHEAVLAETHTNVHVQSIERLTKERDELMTVLCSLRASQTDAQQREWGAYQQVKQAVEMAEEANLEKTRALVQCEHFHNELTRQRERLERELASEQDKISQAREAARSESKKEREELMQTLSSLSQKVAELQGLLDRGERDRNSLNSQLEEAYKKLTVQETDSSKMCAELRFLLSQAQLKKEEAERDVRDISSKLGRQLELAEQEVQKLGVELSGYRQRLEEAQRAEGRARAEAAGLAEGLSRAQRQLHLTRQEKEASERCCGEDMAALTFQAQRRERELTQTLQQMEAQHEKSVRETDALLSAQNSLIRKLKEECHTLGAKLEELAQSSRAEMEQLSLEREHLQESAEKLRGRCEEMEEQCVQHGRMHQRMKQRLQQLDQHCQASSQQVLQLLSRQKQLMQERQQLTEDLHSLKSQVHAGKRMDRLAV", "length": 701 }, "evidence": [ { "id": "A0AAA9TVM1", "url": "https://omabrowser.org/oma/group/A0AAA9TVM1/", "database": "OMA" } ], "glygen_name": "Zebrafish", "common_name": "Zebrafish" }, { "uniprot_canonical_ac": "I3L6U7-1", "protein_name": "SHH signaling and ciliosis regulator SDCCAG8", "gene_name": "SDCCAG8", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MAKSSENSTLEEILGQYQRSLRERANRSIHQLKSALREGDVTIGEDVLDPSFGTHVGNEDAGTAWRELQHSHAVNQLKALLRQQATEESEVSPRRRKMSPSRSPEHEETNMPTVHNLVAIINDQSQYIHHLEAEVKFCKEELSGMKNRVQVVVLENERLQQELKSQKEEEETMREQTLLDASGNVQNSWITPDVDSRVDEAARRSLSHGNANVINAACAGEAEKWKLELERLKLTYEEKSEILESQLRFLRKELAESQKDCEDLKERLKHKESLLAANVSHRVGGLCLKCAQHEAVLSQTHSNVHIQTIERLTKERDDLMSALVSVRSSLTDVQQREASAFEQVKQAVQMTEEANFEKTKALIQCEQLKNELERQTERLEKELASQQEKRTFEKEMMKKEMTKEREDMRSKVLTLSQNIAQLETQVEKATREKISAVNQLEEIQNQLASQEMDVTKVCGEMRYQLNKIKMEKDDAEKEHREYRTKTKRDLEIKDQEIEKLRLEVSESKQRLEQEQQKATQAREECLKLTELLGESEHQLHLTRLEKDSIQQSFSNEAKAQALQAQQREQELTQKIQQMEAQHDKTESEQYSLLTSQNTFLIKLKEECCTLAKKLEQISQKSRSEIAQLSQEKRYTYDKLEKLQRRNDELEEQCVQHGQLHEIMKQRLKQLDKHGQATAQQLVQLLNKQNQLLQERQSLSEEVGRLRAQLPSMPQSDC", "length": 717 }, "evidence": [ { "id": "A0AAA9TVM1", "url": "https://omabrowser.org/oma/group/A0AAA9TVM1/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "Q80UF4-1", "protein_name": "Serologically defined colon cancer antigen 8 homolog", "gene_name": "Sdccag8", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MAKSPGNSTLEDSLGQYQRSLRERANRSIHQLKCALREVDVTVEEDALDPSTSINVENEDTGVAWHELQHSHAVNQLKALLRQQTNKENETSPPRRRKLSPSRPSECDDGSMPTMHNLVPIINDQSQYIHHLEAEVKFCKDELSGMKNRVQVVVLENERLQQELKSQRPEETLREQTFLDASGNMQNSWIMTREDSRVDEAAKRPFSHGDAETGKTASTGDANKWKLELERLKLTYEAKTDLLESQLMLLRKDLAEYQKTCEDLKERLKHKESLLAASASSRVGGLCLKCAQHEAVLSQTHSNVHIQTIERLTKERDDLMSVLVSVRSSLAEAQKRETSAYEQVKHAVQMTEEANFEKTKALIQCEQLKSELERQTERLEKELASQQEKRAVEKEMIKKEVAREREDAESKMLILSQNIAKLEAQVEKVTREKTAAVSHLEEIQNHVASQEMDVTKVCGEMRFQLNKTKMEKDEVEKEHREYKAKSHKDLEMKVQEIEKLRLELSESEQHVEQEQQKAARARQECLRVTELLGEAERQLHLTRLEKDSIQQSFSNEAKAQALQAQQREQELTQKIQQMETQHDKTESEQYLLLTSQNTFLTKLKEECCLLAKKLEKVSLKSRSQIVRLSQEKRYLCDKLEKLQKRNDELEEQCIQHGRVHETMKERLRQLDKHGQATAQQLVQLLNKQNQLLLERQNLSEEVARLRAQLPSMPQSDC", "length": 717 }, "evidence": [ { "id": "A0AAA9TVM1", "url": "https://omabrowser.org/oma/group/A0AAA9TVM1/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q86SQ7-1", "protein_name": "Serologically defined colon cancer antigen 8", "gene_name": "SDCCAG8", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MAKSPENSTLEEILGQYQRSLREHASRSIHQLTCALKEGDVTIGEDAPNLSFSTSVGNEDARTAWPELQQSHAVNQLKDLLRQQADKESEVSPSRRRKMSPLRSLEHEETNMPTMHDLVHTINDQSQYIHHLEAEVKFCKEELSGMKNKIQVVVLENEGLQQQLKSQRQEETLREQTLLDASGNMHNSWITTGEDSGVGETSKRPFSHDNADFGKAASAGEQLELEKLKLTYEEKCEIEESQLKFLRNDLAEYQRTCEDLKEQLKHKEFLLAANTCNRVGGLCLKCAQHEAVLSQTHTNVHMQTIERLVKERDDLMSALVSVRSSLADTQQREASAYEQVKQVLQISEEANFEKTKALIQCDQLRKELERQAERLEKELASQQEKRAIEKDMMKKEITKEREYMGSKMLILSQNIAQLEAQVEKVTKEKISAINQLEEIQSQLASREMDVTKVCGEMRYQLNKTNMEKDEAEKEHREFRAKTNRDLEIKDQEIEKLRIELDESKQHLEQEQQKAALAREECLRLTELLGESEHQLHLTRQEKDSIQQSFSKEAKAQALQAQQREQELTQKIQQMEAQHDKTENEQYLLLTSQNTFLTKLKEECCTLAKKLEQISQKTRSEIAQLSQEKRYTYDKLGKLQRRNEELEEQCVQHGRVHETMKQRLRQLDKHSQATAQQLVQLLSKQNQLLLERQSLSEEVDRLRTQLPSMPQSDC", "length": 713 }, "evidence": [ { "id": "A0AAA9TVM1", "url": "https://omabrowser.org/oma/group/A0AAA9TVM1/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" } ], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 7, "go_terms": [ { "name": "centrosome", "id": "GO:0005813", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005813", "evidence": [ { "database": "UniProtKB", "id": "A0AAA9TVM1", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TVM1" } ], "pmid": "" }, { "name": "photoreceptor cell cilium", "id": "GO:0097733", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0097733", "evidence": [ { "database": "UniProtKB", "id": "A0AAA9TVM1", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TVM1" } ], "pmid": "" }, { "name": "cytoplasm", "id": "GO:0005737", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005737", "evidence": [ { "database": "UniProtKB", "id": "A0AAA9TVM1", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TVM1" } ], "pmid": "" }, { "name": "cell-cell junction", "id": "GO:0005911", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005911", "evidence": [ { "database": "UniProtKB", "id": "A0AAA9TVM1", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TVM1" } ], "pmid": "" }, { "name": "centriole", "id": "GO:0005814", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005814", "evidence": [ { "database": "UniProtKB", "id": "A0AAA9TVM1", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TVM1" } ], "pmid": "" }, { "name": "centriolar satellite", "id": "GO:0034451", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0034451", "evidence": [ { "database": "UniProtKB", "id": "A0AAA9TVM1", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TVM1" } ], "pmid": "" }, { "name": "ciliary basal body", "id": "GO:0036064", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0036064", "evidence": [ { "database": "UniProtKB", "id": "A0AAA9TVM1", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TVM1" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 6, "go_terms": [ { "name": "centrosome cycle", "id": "GO:0007098", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007098", "evidence": [ { "database": "UniProtKB", "id": "A0AAA9TVM1", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TVM1" } ], "pmid": "" }, { "name": "establishment of cell polarity", "id": "GO:0030010", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030010", "evidence": [ { "database": "UniProtKB", "id": "A0AAA9TVM1", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TVM1" } ], "pmid": "" }, { "name": "regulation of cilium assembly", "id": "GO:1902017", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:1902017", "evidence": [ { "database": "UniProtKB", "id": "A0AAA9TVM1", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TVM1" } ], "pmid": "" }, { "name": "tube formation", "id": "GO:0035148", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0035148", "evidence": [ { "database": "UniProtKB", "id": "A0AAA9TVM1", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TVM1" } ], "pmid": "" }, { "name": "neuron migration", "id": "GO:0001764", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0001764", "evidence": [ { "database": "UniProtKB", "id": "A0AAA9TVM1", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TVM1" } ], "pmid": "" }, { "name": "microtubule organizing center organization", "id": "GO:0031023", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0031023", "evidence": [ { "database": "UniProtKB", "id": "A0AAA9TVM1", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TVM1" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 208, "end_pos": 210, "annotation": "n_glycosylation_sequon" }, { "start_pos": 26, "end_pos": 28, "annotation": "n_glycosylation_sequon" }, { "start_pos": 276, "end_pos": 278, "annotation": "n_glycosylation_sequon" }, { "start_pos": 464, "end_pos": 466, "annotation": "n_glycosylation_sequon" }, { "start_pos": 53, "end_pos": 55, "annotation": "n_glycosylation_sequon" }, { "start_pos": 7, "end_pos": 9, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" }, { "name": "homologset.oma", "label": "OMA Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 208, "end_pos": 210 }, { "start_pos": 26, "end_pos": 28 }, { "start_pos": 276, "end_pos": 278 }, { "start_pos": 464, "end_pos": 466 }, { "start_pos": 53, "end_pos": 55 }, { "start_pos": 7, "end_pos": 9 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ], "tool_support": { "graph_view": "yes" } }, { "uniprot_canonical_ac": "A0AAA9TTI9-1", "uniprot_ac": "A0AAA9TTI9", "uniprot_id": "A0AAA9TTI9_BOVIN", "mass": { "chemical_mass": 68695.0, "monoisotopic_mass": 68695.0 }, "refseq": { "ac": "XP_059745012", "name": "zinc finger CCHC domain-containing protein 7 isoform X1", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_059745012" }, "gene_names": [ { "name": "ZCCHC7", "type": "recommended", "evidence": [ { "id": "A0AAA9TTI9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TTI9" } ] }, { "name": "ZCCHC7", "type": "synonym", "evidence": [ { "id": "XP_059745012", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_059745012" } ] } ], "protein_names": [ { "name": "Zinc finger CCHC domain-containing protein 7", "type": "recommended", "evidence": [ { "id": "A0AAA9TTI9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TTI9/entry#names_and_taxonomy" } ] }, { "name": "TRAMP-like complex RNA-binding factor ZCCHC7", "type": "synonym", "evidence": [ { "id": "A0AAA9TTI9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TTI9/entry#names_and_taxonomy" } ] }, { "name": "zinc finger CCHC domain-containing protein 7 isoform X1", "type": "synonym", "evidence": [ { "id": "XP_059745012", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_059745012" } ] } ], "function": [], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Bos taurus", "taxid": 9913, "evidence": [ { "database": "UniProtKB", "id": "A0AAA9TTI9", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TTI9" } ], "common_name": "Bovine", "glygen_name": "Bovine", "reference_species": "Bos taurus [9913]" } ], "gene": [ { "name": "ZCCHC7", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TTI9", "locus": { "chromosome": "8", "start_pos": 61488483, "end_pos": 61209453, "strand": "-", "evidence": [ { "database": "Ensembl Gene", "id": "ENSBTAG00000025859", "url": "https://www.ensembl.org/id/ENSBTAG00000025859" } ] } } ], "crossref": [ { "id": "A0AAA9TTI9", "url": "https://alphafold.ebi.ac.uk/entry/A0AAA9TTI9", "database": "AlphaFoldDB", "categories": [] }, { "id": "ENSBTAG00000025859", "url": "https://bgee.org/?page=gene&gene_id=ENSBTAG00000025859", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "511821", "url": "https://www.ncbi.nlm.nih.gov/gene/511821", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR001878", "url": "https://www.ebi.ac.uk/interpro/entry/IPR001878", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR036875", "url": "https://www.ebi.ac.uk/interpro/entry/IPR036875", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR051644", "url": "https://www.ebi.ac.uk/interpro/entry/IPR051644", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "HFGHACI", "url": "https://omabrowser.org/oma/group/HFGHACI/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "F1MUH8", "url": "https://www.orthodb.org/?gene=F1MUH8", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR46543", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR46543", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR46543:SF1", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR46543:SF1", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00098", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00098", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "XP_059745012", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_059745012", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0AAA9RZ51", "url": "https://www.uniprot.org/uniprotkb/A0AAA9RZ51", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0AAA9RZ51-1", "url": "https://www.uniprot.org/uniprotkb/A0AAA9RZ51-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0AAA9TTI9", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TTI9", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0AAA9TTI9-1", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TTI9-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "F1MUH8", "url": "https://www.uniprot.org/uniprotkb/F1MUH8", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "F1MUH8-1", "url": "https://www.uniprot.org/uniprotkb/F1MUH8-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MMFGGYETIEAYEDELYREESSSELSVDSEVEFQLYSQVHYAQDLDNVIREEEHEDRNSGNSESFSSKPNQKNLIVLSDSEVIQLSDGSEVITLSDEDSIYRCERKNFRVHAKEKTQGSPASLHSNDLADKKCKRDIEKSKPGERSGTIQEVMIIEVSSSEEEESTISESDNVESWMLLGCEVDDKDDDILLNLVGCEKSVNEGDVPDPGIKPKSPWSPALQADCLPTKPSRKPLDDPCTFKSLLKDSAFGEDDVNWFISDKDIEAQIGNKRSSGRWTHRYYTANKNVTCRNCDKCGHLSKNCPFPQKVRPCCLCSERGHLQYACPARFCLGCSLPMSSTHRCLERASWRKRCDRCDMIGHYADACPEIWRQYHLTTKPGPPKKPKTPSGQSTLVYCYNCGQEGHYGHECTERRMFNQTFPTSPFIYYYDDKYKIRERDQRIKRKVKELQKNGDLPRKFKRPHMEAADKRPRDIRTSHASWKNNRWPQEKKETQKETMSRNMREREKHRKAARCHEDDEDFPRGPRVHSTPGTSKTQKPHKPFHHSSHYLKPREDRLSKEGKRGKHKKKESCVEEDSNDNLFLIKQRKKKSKL", "length": 593, "header": "tr|A0AAA9TTI9-1|A0AAA9TTI9_BOVIN Isoform 1 of Zinc finger CCHC domain-containing protein 7 OS=Bos taurus OX=9913 GN=ZCCHC7 PE=4 SV=1 CANONICAL=A0AAA9TTI9-1" }, "isoforms": [ { "isoform_ac": "A0AAA9RZ51-1", "url": "https://www.uniprot.org/uniprotkb/A0AAA9RZ51/entry", "sequence": { "sequence": "MMFGGYETIEAYEDELYREESSSELSVDSEVEFQLYSQVHYAQDLDNVIREEEHEDRNSGNSESFSSKPNQKNLIVLSDSEVIQLSDGSEVITLSDEDSIYRCERKNFRVHAKEKTQGSPASLHSNDLADKKCKRDIEKSKPGERSGTIQEVMIIEVSSSEEEESTISESDNVESWMLLGCEVDDKDDDILLNLVGCEKSVNEGEDDVNWFISDKDIEAQIGNKRSSGRWTHRYYTANKNVTCRNCDKCGHLSKNCPFPQKVRPCCLCSERGHLQYACPARFCLGCSLPMSSTHRCLERASWRKRCDRCDMIGHYADACPEIWRQYHLTTKPGPPKKPKTPSGQSTLVYCYNCGQEGHYGHECTERRMFNQTFPTSPFIYYYDDKYKIRERDQRIKRKVKELQKNGDLPRKFKRPHMEAADKRPRDIRTSHASWKNNRWPQEKKETQKETMSRNMREREKHRKAARCHEDDEDFPRGPRVHSTPGTSKTQKPHKPFHHSSHYLKPREDRLSKEGKRGKHKKKESCVEEDSNDNLFLIKQRKKKSKL", "length": 546, "header": "tr|A0AAA9RZ51-1|A0AAA9TTI9_BOVIN Computationally mapped isoform of Zinc finger CCHC domain-containing protein 7 OS=Bos taurus OX=9913 GN=ZCCHC7 PE=4 SV=1 CANONICAL=A0AAA9TTI9-1" }, "locus": { "chromosome": "8", "start_pos": 61488157, "end_pos": 61215357, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000130439.2", "url": "https://www.ensembl.org/id/ENSBTAT00000130439.2" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000075055.1", "url": "https://www.ensembl.org/id/ENSBTAP00000075055.1" } ] } }, { "isoform_ac": "A0AAA9TTI9-1", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TTI9/entry", "sequence": { "sequence": "MMFGGYETIEAYEDELYREESSSELSVDSEVEFQLYSQVHYAQDLDNVIREEEHEDRNSGNSESFSSKPNQKNLIVLSDSEVIQLSDGSEVITLSDEDSIYRCERKNFRVHAKEKTQGSPASLHSNDLADKKCKRDIEKSKPGERSGTIQEVMIIEVSSSEEEESTISESDNVESWMLLGCEVDDKDDDILLNLVGCEKSVNEGDVPDPGIKPKSPWSPALQADCLPTKPSRKPLDDPCTFKSLLKDSAFGEDDVNWFISDKDIEAQIGNKRSSGRWTHRYYTANKNVTCRNCDKCGHLSKNCPFPQKVRPCCLCSERGHLQYACPARFCLGCSLPMSSTHRCLERASWRKRCDRCDMIGHYADACPEIWRQYHLTTKPGPPKKPKTPSGQSTLVYCYNCGQEGHYGHECTERRMFNQTFPTSPFIYYYDDKYKIRERDQRIKRKVKELQKNGDLPRKFKRPHMEAADKRPRDIRTSHASWKNNRWPQEKKETQKETMSRNMREREKHRKAARCHEDDEDFPRGPRVHSTPGTSKTQKPHKPFHHSSHYLKPREDRLSKEGKRGKHKKKESCVEEDSNDNLFLIKQRKKKSKL", "length": 593, "header": "tr|A0AAA9TTI9-1|A0AAA9TTI9_BOVIN Isoform 1 of Zinc finger CCHC domain-containing protein 7 OS=Bos taurus OX=9913 GN=ZCCHC7 PE=4 SV=1 CANONICAL=A0AAA9TTI9-1" }, "locus": { "chromosome": "8", "start_pos": 61488157, "end_pos": 61215357, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000096871.1", "url": "https://www.ensembl.org/id/ENSBTAT00000096871.1" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000099854.1", "url": "https://www.ensembl.org/id/ENSBTAP00000099854.1" } ] } }, { "isoform_ac": "F1MUH8-1", "url": "https://www.uniprot.org/uniprotkb/F1MUH8/entry", "sequence": { "sequence": "MMFGGYETIEAYEDELYREESSSELSVDSEVEFQLYSQVHYAQDLDNVIREEEHEDRNSGNSESFSSKPNQKNLIVLSDSEVIQLSDGSEVITLSDEDSIYRCERKNFRVHAKEKTQGSPASLHSNDLADKKCKRDIEKSKPGERSGTIQEVMIIEVSSSEEEESTISESDNVESWMLLGCEVDDKDDDILLNLVGCEKSVNEGEDDVNWFISDKDIEAQIGNKRSSGRWTHRYYTANKNVTCRNCDKCGHLSKNCPFPQKVRPCCLCSERGHLQYACPARFCLGCSLPMSSTHRCLERASWRKRCDRCDMIGHYADACPEIWRQYHLTTKPGPPKKPKTPSGQSTLVYCYNCGQEGHYGHECTERRMFNQTFPTSPFIYYYDDKYKIRERDQRIKRKVKELQKNGDLPRKFKRPHMEAADKRPRDIRTSHASWKNNRWPQEKKETQKETMSRNMREREKHRKAARCHEDDEDFPRGPRVHSTPGTSKTQKPHKPFHHSSHYLKPREDRLSKEGKRGKHKKKESCVEEDSNDNLFLIKQRKKKSKLHI", "length": 548, "header": "tr|F1MUH8-1|F1MUH8_BOVIN Computationally mapped isoform of Zinc finger CCHC domain-containing protein 7 OS=Bos taurus OX=9913 GN=ZCCHC7 PE=4 SV=3 CANONICAL=A0AAA9TTI9-1" }, "locus": { "chromosome": "8", "start_pos": 61488283, "end_pos": 61215357, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000028791.5", "url": "https://www.ensembl.org/id/ENSBTAT00000028791.5" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000028791.4", "url": "https://www.ensembl.org/id/ENSBTAP00000028791.4" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [], "orthologs": [ { "uniprot_canonical_ac": "A0A8M3B5M8-1", "protein_name": "Zinc finger CCHC domain-containing protein 7", "gene_name": "zcchc7", "tax_id": 7955, "organism": "Danio rerio", "sequence": { "sequence": "MCSPLSNHVCVAPYFCAQAVEITLSLLGFLPRALLEMFSGLQERYDHEDELYRDEEDSSGLSDSDSELEFRLYSQLHYNAEFQENHEESSKVQPLVPQTQLQPETMPPAPPVDVIVIDSGPDSFTVSDSTEDDESVCANKVQSLKHCKRKSQPSRFRSPSPPQVQAGRSSPDDVVVLDSDLEQSSSESEPPFVEDLDSDTDSDSDSDGLENWMILGKGRQDGDQSIQLNLAQSSFVNTEYVNYRGQEQKWTVSEKDKQAQIYNKGHGPRHVPNRSTYRYYTEKSITCRNCNKTGHLSKNCPTLKKVPCCSLCGLRGHLLRTCPNRHCSNCSLPGHTSDDCLERAFWYKRCHRCGMTGHFIDACPQIWRQYHLTTTAGPIRKSADPKACQKRAYCYNCSRKGHFGHQCSQRRMYNWSYPSLPVITYYDTVNDIKCRDFRLKKKAREMQDAGLISPDGGVVTFTPQPPRKKQKVSHSPHPYSNNTNNHHTPKKRIAHTPKHNPQTNQQNTHWRVKQNSKKPGPHGKNTPQSKEFKSQNKEAKNKKRKKKKAAVIDEDADFPRGSKKSPHKAGFHSSTQKANVKPVKLFGVEKNHMKKKDKSKKKERIQRKRQQKAAKDSAAYPTDENLFQIKQRKVKRSK", "length": 638 }, "evidence": [ { "id": "A0AAA9TTI9", "url": "https://omabrowser.org/oma/group/A0AAA9TTI9/", "database": "OMA" } ], "glygen_name": "Zebrafish", "common_name": "Zebrafish" }, { "uniprot_canonical_ac": "A0A8V0X767-1", "protein_name": "Zinc finger CCHC domain-containing protein 7", "gene_name": "ZCCHC7", "tax_id": 9031, "organism": "Gallus gallus", "sequence": { "sequence": "MFYDGEDTEESDVYEDELYREESSSEPSIDSEVEFHLYSQVHYSQNLAEASSLEVSEEAEDVVGFIEQSSGLTVAPLEDKNVIELLDCDDQISDDPEIIVLSDTPEEDSVYKSKAQKSTSSVAEGKIHIHGSSMVNHAKATERNAPYPAGSGREVSRQGPSGKLTSVSSGPLTVQEVMIIDDSSSDEEESMISESDNVESWMLLGCSADDKDKDIMLNLEGCGTPIGEGDTDVDWSISNKDLEAQICNYASVRRTSVRYYTADKNVTCRNCGRPGHLSKNCPVPKKTPPCCLCAERGHLQNTCPARFCLNCCLPGHYFRECLERSYWNKHCSRCDMKGHYADACPEIWRQYHLTTNPGPIKAASSHSEHSAAVYCYNCSRKGHFGYECSEKRMRGSMFPASPFIHYYDDECDLKRRANRLKRKIAELQEAGLLPVQPETPWQEEKHGGHSCKKKPWEEHSKCNKDECRRKRKSSSRADKQRAKKHRSDVERGHEMEDDFPRGHHKQTSRGSKKHHKSILQAFGSKKEHGQQLLEAAKRKKKRKKQRDASPDFNENLFLIKQRRKKSKQKSSFW", "length": 573 }, "evidence": [ { "id": "A0AAA9TTI9", "url": "https://omabrowser.org/oma/group/A0AAA9TTI9/", "database": "OMA" } ], "glygen_name": "Chicken", "common_name": "Chicken" }, { "uniprot_canonical_ac": "B1AX39-1", "protein_name": "Zinc finger CCHC domain-containing protein 7", "gene_name": "Zcchc7", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MFGGYETIEAFEDDLYRDDSSSELSVDSEVEFQLYSQVHYAQSIHNANKEEGYEEKNCENSETVSSQPNQKNLIVLSDSEVIQLSDTSEVITLSDEDSIYRCKRKNIEVQAEEKTQSPATSHSNKVAQKCKRNNKKPKPEERPGVIREVMIIEVSSNEEEESTTSENENVESWMLLGSEEDGKDNDILLNLVGCETAGAEDDVNWFISDKDIEAKIDNNRSSGRWNNRYYSVNKNVTCRNCDKRGHLSKNCPLPQKVRACCLCSERGHLQYGCPARYCLDCSLPMSSNHRCFERLSWRKRCDRCDMIGHHADACPEIWRQYHLTTKPGPPKKPKTPSGQSALVYCYNCAQKGHYGHECTERRMFNQTFPTSPFIYCYDGKYDIQQRDRRIKRKVKDLKKNGDFPRQFKRPHVEETDKRRHHDMRKSRSPRKYRRWPRENKETQKEKTRSREGKTHRRGHQPRGEDEDFPRGSKPNASGCANNQKPSKSLHHASHYHRLREERLLRESKRSKPKKRKSTEDGSHDDLFLIKQKKKKPKPSGL", "length": 541 }, "evidence": [ { "id": "A0AAA9TTI9", "url": "https://omabrowser.org/oma/group/A0AAA9TTI9/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "B1WC15-1", "protein_name": "Zinc finger CCHC domain-containing protein 7", "gene_name": "Zcchc7", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MFGGFETIEAFEDDLYRDDSSSELSVDSEVEFQLYSQVHYSQNIHNANEEEGYEEKNCESSETVSIQPDQKNLIVLSDSEVIQLSDTSEVITLSDEDSIYRCKRKNIEVQAQEKTQSPATPRSNKVANKCKRSNKKPEPEESPSTIREVMIIEVSSDEEEESTISENENVESWMLLGCEEDDKDNDILLNLVGCKDAGAEGENDVNWFISDKDIEAKIDNNRSSGRWNNRYYSVNKNVTCRNCDKRGHLSKNCPLPQKVRPCCLCSERGHLQYGCPARYCLDCSLPMSSTHRCFERSSWRKRCDRCDMIGHYADACPEIWRQYHLTTKPGPPKKPKTPSGQSALVYCYNCAQKGHYGHECTERRMFNQAFPTSPFIYCYDDKYDIQQRDRRIKRKLKDIKKNGDFPRQFKRPHGEETDRYHHDRRKSRFSGKRSRWPRESKETQKEKTRGREGEKHRRDRQPRDEDEDFPRGLKPNSSSSSNSQKPSKSLHQASHYHRLREEKLRRESMRSKPKKRKFVEDGSHDDLFLIKQRKKKPKSSGF", "length": 542 }, "evidence": [ { "id": "A0AAA9TTI9", "url": "https://omabrowser.org/oma/group/A0AAA9TTI9/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "Q8N3Z6-1", "protein_name": "Zinc finger CCHC domain-containing protein 7", "gene_name": "ZCCHC7", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MMFGGYETIEAYEDDLYRDESSSELSVDSEVEFQLYSQIHYAQDLDDVIREEEHEEKNSGNSESSSSKPNQKKLIVLSDSEVIQLSDGSEVITLSDEDSIYRCKGKNVRVQAQENAHGLSSSLQSNELVDKKCKSDIEKPKSEERSGVIREVMIIEVSSSEEEESTISEGDNVESWMLLGCEVDDKDDDILLNLVGCENSVTEGEDGINWSISDKDIEAQIANNRTPGRWTQRYYSANKNIICRNCDKRGHLSKNCPLPRKVRRCFLCSRRGHLLYSCPAPLCEYCPVPKMLDHSCLFRHSWDKQCDRCHMLGHYTDACTEIWRQYHLTTKPGPPKKPKTPSRPSALAYCYHCAQKGHYGHECPEREVYDPSPVSPFICYYDDKYEIQEREKRLKQKIKVLKKNGVIPEPSKLPYIKAANENPHHDIRKGRASWKSNRWPQENKETQKEMKNKNRNWEKHRKADRHREVDEDFPRGPKTYSSPGSFKTQKPSKPFHRSSHYHTSREDKSPKEGKRGKQKKKERCWEDDDNDNLFLIKQRKKKS", "length": 543 }, "evidence": [ { "id": "A0AAA9TTI9", "url": "https://omabrowser.org/oma/group/A0AAA9TTI9/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" } ], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 2, "go_terms": [ { "name": "nucleolus", "id": "GO:0005730", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005730", "evidence": [ { "database": "UniProtKB", "id": "A0AAA9TTI9", "url": 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"UniProtKB", "categories": [ "Protein" ] }, { "id": "A0AAA9RZN1-1", "url": "https://www.uniprot.org/uniprotkb/A0AAA9RZN1-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0AAA9SH17", "url": "https://www.uniprot.org/uniprotkb/A0AAA9SH17", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0AAA9SH17-1", "url": "https://www.uniprot.org/uniprotkb/A0AAA9SH17-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0AAA9SKE7", "url": "https://www.uniprot.org/uniprotkb/A0AAA9SKE7", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0AAA9SKE7-1", "url": "https://www.uniprot.org/uniprotkb/A0AAA9SKE7-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0AAA9T198", "url": "https://www.uniprot.org/uniprotkb/A0AAA9T198", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0AAA9T198-1", "url": "https://www.uniprot.org/uniprotkb/A0AAA9T198-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": 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"database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MVPGAAGWCCLVLWLPACVAAHGLRIHDYLYFQVLSPGDIRYIFTATPAKDFGGIFHTRYEQIHLVPAEPSEACGELSNGFFIQDQIALVERGGCSFLSKTRVVQEHGGRAVIISDNAVDNDSFYVEMIQDSTQRTADIPALFLLGRDGYMIRRSLEQHGLPWAIISIPVNVTSIPTFELLQPPWTFWEETEAQRGYKACPGSFRTSAQTANPGSRQPPAQELRKRWFSPRGKASLFCSLVLGIHTGPQRSPALRPEKRLHSRYRRDEG", "length": 269, "header": "tr|A0AAA9TV69-1|A0AAA9TV69_BOVIN Isoform 1 of Protease-associated domain-containing protein 1 OS=Bos taurus OX=9913 GN=PRADC1 PE=4 SV=1 CANONICAL=A0AAA9TV69-1" }, "isoforms": [ { "isoform_ac": "A0AAA9RZN1-1", "url": "https://www.uniprot.org/uniprotkb/A0AAA9RZN1/entry", "sequence": { "sequence": "MVPGAAGWCCLVLWLPACVAAHGLRIHDYLYFQVLSPGDIRYIFTATPAKDFGGIFHTRYEQIHLVPAEPSEACGELSNGFFIQDQIALVERGGCSFLSKTRVVQEHGGRAVIISDNAVDNDSFYVEMIQDSTQRTADIPALFLLGRDGYMIRRSLEQHGLPWAIISIPVNVTSIPTFELLQPPWTFWC", "length": 189, "header": "tr|A0AAA9RZN1-1|A0AAA9TV69_BOVIN Computationally mapped isoform of Protease-associated domain-containing protein 1 OS=Bos taurus OX=9913 GN=PRADC1 PE=4 SV=1 CANONICAL=A0AAA9TV69-1" }, "locus": { "chromosome": "11", "start_pos": 11223105, "end_pos": 11215774, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000113536.2", "url": "https://www.ensembl.org/id/ENSBTAT00000113536.2" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000076548.1", "url": "https://www.ensembl.org/id/ENSBTAP00000076548.1" } ] } }, { "isoform_ac": "A0AAA9SH17-1", "url": "https://www.uniprot.org/uniprotkb/A0AAA9SH17/entry", "sequence": { "sequence": "MVPGAAGWCCLVLWLPACVAAHGLRIHDYLYFQVLSPGDIRYIFTATPAKDFGGIFHTRYEQIHLVPAEPSEACGELSNGFFIQDQIALVERGGCSFLSKTRVVQEHGGRAVIISDNAVDNDSFYVEMIQDSTQRTADIPALFLLGRDGLNSTSPGGTNRGELQREAAPSQCRDSQQLCSTKRPDPSQLRNSPVAVRQSYADGITSMS", "length": 208, "header": "tr|A0AAA9SH17-1|A0AAA9TV69_BOVIN Computationally mapped isoform of Protease-associated domain-containing protein 1 OS=Bos taurus OX=9913 GN=PRADC1 PE=4 SV=1 CANONICAL=A0AAA9TV69-1" }, "locus": { "chromosome": "11", "start_pos": 11223514, "end_pos": 11215774, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000100230.2", "url": "https://www.ensembl.org/id/ENSBTAT00000100230.2" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000085497.1", "url": "https://www.ensembl.org/id/ENSBTAP00000085497.1" } ] } }, { "isoform_ac": "A0AAA9SKE7-1", "url": "https://www.uniprot.org/uniprotkb/A0AAA9SKE7/entry", "sequence": { "sequence": "MVRYHRVGVARRVRGWASVRATRIVGLRIHDYLYFQVLSPGDIRYIFTATPAKDFGGIFHTRYEQIHLVPAEPSEACGELSNGFFIQDQIALVERGGCSFLSKTRVVQEHGGRAVIISDNAVDNDSFYVEMIQDSTQRTADIPALFLLGRDGYMIRRSLEQHGLPWAIISIPVNVTSIPTFELLQPPWTFW", "length": 191, "header": "tr|A0AAA9SKE7-1|A0AAA9TV69_BOVIN Computationally mapped isoform of Protease-associated domain-containing protein 1 OS=Bos taurus OX=9913 GN=PRADC1 PE=4 SV=1 CANONICAL=A0AAA9TV69-1" }, "locus": { "chromosome": "11", "start_pos": 11219409, "end_pos": 11214717, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000089545.2", "url": "https://www.ensembl.org/id/ENSBTAT00000089545.2" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000084352.1", "url": "https://www.ensembl.org/id/ENSBTAP00000084352.1" } ] } }, { "isoform_ac": "A0AAA9T198-1", "url": "https://www.uniprot.org/uniprotkb/A0AAA9T198/entry", "sequence": { "sequence": "ARPGPGATGHLGDPANSEQGLRIHDYLYFQVLSPGDIRYIFTATPAKDFGGIFHTRYEQIHLVPAEPSEACGELSNGFFIQDQIALVERGGCSFLSKTRVVQEHGGRAVIISDNAVDNDSFYVEMIQDSTQRTADIPALFLLGRDGEETEAQRGYKACPGSWGSTLDLRGALLLDLRNVCTADIDETRDESKLGSWSSHLLPSPLCPMHSGTIHVTVACLSSHPPQSIPVKACH", "length": 234, "header": "tr|A0AAA9T198-1|A0AAA9TV69_BOVIN Computationally mapped isoform of Protease-associated domain-containing protein 1 OS=Bos taurus OX=9913 GN=PRADC1 PE=4 SV=2 CANONICAL=A0AAA9TV69-1" }, "locus": { "chromosome": "11", "start_pos": 11220304, "end_pos": 11215896, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000107564.2", "url": "https://www.ensembl.org/id/ENSBTAT00000107564.2" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000090351.2", "url": "https://www.ensembl.org/id/ENSBTAP00000090351.2" } ] } }, { "isoform_ac": "A0AAA9TIQ1-1", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TIQ1/entry", "sequence": { "sequence": "SGRGWRTSLSASWAGGHGSPWGPREFGARQVQTPAPGVGLRIHDYLYFQVLSPGDIRYIFTATPAKDFGGIFHTRYEQIHLVPAEPSEACGELSNGFFIQDQIALVERGGCSFLSKTRVVQEHGGRAVIISDNAVDNDSFYVEMIQDSTQRTADIPALFLLGRDGYMIRRSLEQHGLPWAIISIPVNVTSIPTFELLQPPWTFW", "length": 204, "header": "tr|A0AAA9TIQ1-1|A0AAA9TV69_BOVIN Computationally mapped isoform of Protease-associated domain-containing protein 1 OS=Bos taurus OX=9913 GN=PRADC1 PE=4 SV=2 CANONICAL=A0AAA9TV69-1" }, "locus": { "chromosome": "11", "start_pos": 11219409, "end_pos": 11215868, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000125215.2", "url": "https://www.ensembl.org/id/ENSBTAT00000125215.2" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000098193.2", "url": "https://www.ensembl.org/id/ENSBTAP00000098193.2" } ] } }, { "isoform_ac": "A0AAA9TV69-1", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TV69/entry", "sequence": { "sequence": "MVPGAAGWCCLVLWLPACVAAHGLRIHDYLYFQVLSPGDIRYIFTATPAKDFGGIFHTRYEQIHLVPAEPSEACGELSNGFFIQDQIALVERGGCSFLSKTRVVQEHGGRAVIISDNAVDNDSFYVEMIQDSTQRTADIPALFLLGRDGYMIRRSLEQHGLPWAIISIPVNVTSIPTFELLQPPWTFWEETEAQRGYKACPGSFRTSAQTANPGSRQPPAQELRKRWFSPRGKASLFCSLVLGIHTGPQRSPALRPEKRLHSRYRRDEG", "length": 269, "header": "tr|A0AAA9TV69-1|A0AAA9TV69_BOVIN Isoform 1 of Protease-associated domain-containing protein 1 OS=Bos taurus OX=9913 GN=PRADC1 PE=4 SV=1 CANONICAL=A0AAA9TV69-1" }, "locus": { "chromosome": "11", "start_pos": 11220168, "end_pos": 11215774, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000105017.2", "url": "https://www.ensembl.org/id/ENSBTAT00000105017.2" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000102515.1", "url": "https://www.ensembl.org/id/ENSBTAP00000102515.1" } ] } }, { "isoform_ac": "A0ABI0P5I6-1", "url": "https://www.uniprot.org/uniprotkb/A0ABI0P5I6/entry", "sequence": { "sequence": "MVPGAAGWCCLVLWLPACVAAHGLRIHDYLYFQVLSPGDIRYIFTATPAKDFGGIFHTRYEQIHLVPAEPSEACGELSNGFFIQDQIALVERGGCSFLSKTRVVQEHGGRAVIISDNAVDNDSFYVEMIQDSTQRTADIPALFLLGRDGEETEAQRGYKACPGSFRTSAQTANPGSRQPPAQELRKRWFSPRGKASLFCSLVLGIHTGPQRSPALRPEKRLHSRYRRDEG", "length": 230, "header": "tr|A0ABI0P5I6-1|A0ABI0P5I6_BOVIN Computationally mapped isoform of Protease-associated domain-containing protein 1 OS=Bos taurus OX=9913 GN=PRADC1 PE=4 SV=1 CANONICAL=A0AAA9TV69-1" }, "locus": { "chromosome": "11", "start_pos": 11220168, "end_pos": 11215774, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000149533.1", "url": "https://www.ensembl.org/id/ENSBTAT00000149533.1" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000106673.1", "url": "https://www.ensembl.org/id/ENSBTAP00000106673.1" } ] } }, { "isoform_ac": "F6Q1Y3-1", "url": "https://www.uniprot.org/uniprotkb/F6Q1Y3/entry", "sequence": { "sequence": "INPQRGLRIHDYLYFQVLSPGDIRYIFTATPAKDFGGIFHTRYEQIHLVPAEPSEACGELSNGFFIQDQIALVERGGCSFLSKTRVVQEHGGRAVIISDNAVDNDSFYVEMIQDSTQRTADIPALFLLGRDGYMIRRSLEQHGLPWAIISIPVNVTSIPTFELLQPPWTFW", "length": 171, "header": "tr|F6Q1Y3-1|F6Q1Y3_BOVIN Computationally mapped isoform of Protease-associated domain-containing protein 1 OS=Bos taurus OX=9913 GN=PRADC1 PE=4 SV=1 CANONICAL=A0AAA9TV69-1" }, "locus": { "chromosome": "11", "start_pos": 11219409, "end_pos": 11217589, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000011546.7", "url": "https://www.ensembl.org/id/ENSBTAT00000011546.7" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000011546.5", "url": "https://www.ensembl.org/id/ENSBTAP00000011546.5" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [], "orthologs": [], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 1, "go_terms": [ { "name": "extracellular region", "id": "GO:0005576", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005576", "evidence": [ { "database": "UniProtKB", "id": "A0AAA9TV69", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TV69" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 121, "end_pos": 123, "annotation": "n_glycosylation_sequon" }, { "start_pos": 171, "end_pos": 173, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A0AAA9TV69", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TV69" }, { "id": "PF02225", "database": "Pfam", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF02225" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "PA", "eco_id": "ECO_0000259", "start_pos": 65, "end_pos": 149, "start_aa": "Leu", "end_aa": "Gly", "glycosite_overlap": [] } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 121, "end_pos": 123 }, { "start_pos": 171, "end_pos": 173 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ], "tool_support": { "graph_view": "yes" } }, { "uniprot_canonical_ac": "A0AAA9TTE7-1", "uniprot_ac": "A0AAA9TTE7", "uniprot_id": "A0AAA9TTE7_BOVIN", "mass": { "chemical_mass": 72905.0, "monoisotopic_mass": 72905.0 }, "refseq": {}, "gene_names": [ { "name": "ENOX1", "type": "recommended", "evidence": [ { "id": "A0AAA9TTE7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TTE7" } ] } ], "protein_names": [ { "name": "Ecto-NOX disulfide-thiol exchanger 1", "type": "synonym", "evidence": [ { "id": "A0AAA9TTE7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TTE7/entry#names_and_taxonomy" } ] } ], "function": [], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Bos taurus", "taxid": 9913, "evidence": [ { "database": "UniProtKB", "id": "A0AAA9TTE7", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TTE7" } ], "common_name": "Bovine", "glygen_name": "Bovine", "reference_species": "Bos taurus [9913]" } ], "gene": [ { "name": "ENOX1", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TTE7", "locus": { "chromosome": "12", "start_pos": 13338814, "end_pos": 13682749, "strand": "+", "evidence": [ { "database": "Ensembl Gene", "id": "ENSBTAG00000012434", "url": "https://www.ensembl.org/id/ENSBTAG00000012434" } ] } } ], "crossref": [ { "id": "A0AAA9TTE7", "url": "https://alphafold.ebi.ac.uk/entry/A0AAA9TTE7", "database": "AlphaFoldDB", "categories": [] }, { "id": "cd12228", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd12228", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "615969", "url": "https://www.ncbi.nlm.nih.gov/gene/615969", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR000504", "url": "https://www.ebi.ac.uk/interpro/entry/IPR000504", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR012677", "url": "https://www.ebi.ac.uk/interpro/entry/IPR012677", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR034140", "url": "https://www.ebi.ac.uk/interpro/entry/IPR034140", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR035979", "url": "https://www.ebi.ac.uk/interpro/entry/IPR035979", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR038876", "url": "https://www.ebi.ac.uk/interpro/entry/IPR038876", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR056611", "url": "https://www.ebi.ac.uk/interpro/entry/IPR056611", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "bta:615969", "url": "https://www.genome.jp/dbget-bin/www_bget?bta:615969", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "PTHR16001", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR16001", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR16001:SF6", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR16001:SF6", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00076", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00076", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF23267", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF23267", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF27602", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF27602", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "A0AAA9S0A0", "url": "https://www.uniprot.org/uniprotkb/A0AAA9S0A0", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0AAA9S0A0-1", "url": "https://www.uniprot.org/uniprotkb/A0AAA9S0A0-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0AAA9TNB0", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TNB0", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0AAA9TNB0-1", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TNB0-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0AAA9TTE7", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TTE7", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0AAA9TTE7-1", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TTE7-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MMAADTLAGGILSRFAFPPAAADGLGSIAIDATQLNMSVTDPTAWATAMNNLGMVPVGLPGQQLVSDSICVPGFDPGLNMMTGITPINPMIPGLGLVPPPPPTEVAVVKEIIHCKSCTLFPQNPNLPPPSTRERPPGCKTVFVGGLPENATEEIIQEVFEQCGDITAIRKSKKNFCHIRFAEEFMVDKAIYLSGYRMRLGSSTDKKDSGRLHVDFAQARDDFYEWECKQRMRAREERHRRKLEEDRLRPPSPPPIMHYSEHEAALLAEKLKDDSKFSEAITVLLSWIERGEVNRRSANHFYSMVQSANSHVRRLMNEKATHEQEMEEAKENFKNALTGILTQFEQIVAVFNASTRQKAWDHFSKAQRKNIDIWRKHSEELRNAQSEQLMGIRREEEMEMSDDENCDSPTKKMRVDESALAAQAYALKEENDSLRWQLDAYRNEVELLKQEKEQLFRTEENLTKDQQVQFLQQTMQGMQQQLLTIQEELNNKKSELEQAKEEQSHTQALLKVLQEQLKGTKELVETNGHSHEDTNEINVLTVALVNQDRENNTEKRSQGLKSEKEALLIGIISTFLHVHPFGANIEYLWSYMQQLDSKISANEIEMLLMRLPRMFKQEFTGVGATLEKRWKLCAFEGIKTT", "length": 640, "header": "tr|A0AAA9TTE7-1|A0AAA9TTE7_BOVIN Isoform 1 of Ecto-NOX disulfide-thiol exchanger 1 OS=Bos taurus OX=9913 GN=ENOX1 PE=3 SV=1 CANONICAL=A0AAA9TTE7-1" }, "isoforms": [ { "isoform_ac": "A0AAA9S0A0-1", "url": "https://www.uniprot.org/uniprotkb/A0AAA9S0A0/entry", "sequence": { "sequence": "MGSRRRGTQHRREAQGFRQMVLKRSPRTTESDDVRGDPALSHQSAPAAQDARNSVVDAGGVESITQCSQQLPQMMAAAADGLGSIAIDATQLNMSVTDPTAWATAMNNLGMVPVGLPGQQLVSDSICVPGFDPGLNMMTGITPINPMIPGLGLVPPPPPTEVAVVKEIIHCKSCTLFPQNPNLPPPSTRERPPGCKTVFVGGLPENATEEIIQEVFEQCGDITAIRKSKKNFCHIRFAEEFMVDKAIYLSGYRMRLGSSTDKKDSGRLHVDFAQARDDFYEWECKQRMRAREERHRRKLEEDRLRPPSPPPIMHYSEHEAALLAEKLKDDSKFSEAITVLLSWIERGEVNRRSANHFYSMVQSANSHVRRLMNEKATHEQEMEEAKENFKNALTGILTQFEQIVAVFNASTRQKAWDHFSKAQRKNIDIWRKHSEELRNAQSEQLMGIRREEEMEMSDDENCDSPTKKMRVDESALAAQAYALKEENDSLRWQLDAYRNEVELLKQEKEQLFRTEENLTKDQQVQFLQQTMQGMQQQLLTIQEELNNKKSELEQAKEEQSHTQALLKVLQEQLKGTKELVETNGHSHEDTNEINVLTVALVNQDRENNTEKRSQGLKSEKEALLIGIISTFLHVHPFGANIEYLWSYMQQLDSKISANEIEMLLMRLPRMFKQEFTGVGATLEKRWKLCAFEGIKTT", "length": 697, "header": "tr|A0AAA9S0A0-1|A0AAA9TTE7_BOVIN Computationally mapped isoform of Ecto-NOX disulfide-thiol exchanger 1 OS=Bos taurus OX=9913 GN=ENOX1 PE=3 SV=1 CANONICAL=A0AAA9TTE7-1" }, "locus": { "chromosome": "12", "start_pos": 13645801, "end_pos": 13339818, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000117146.2", "url": "https://www.ensembl.org/id/ENSBTAT00000117146.2" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000077057.1", "url": "https://www.ensembl.org/id/ENSBTAP00000077057.1" } ] } }, { "isoform_ac": "A0AAA9TNB0-1", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TNB0/entry", "sequence": { "sequence": "MMAAAADGLGSIAIDATQLNMSVTDPTAWATAMNNLGMVPVGLPGQQLVSDSICVPGFDPGLNMMTGITPINPMIPGLGLVPPPPPTEVAVVKEIIHCKSCTLFPQNPNLPPPSTRERPPGCKTVFVGGLPENATEEIIQEVFEQCGDITAIRKSKKNFCHIRFAEEFMVDKAIYLSGYRMRLGSSTDKKDSGRLHVDFAQARDDFYEWECKQRMRAREERHRRKLEEDRLRPPSPPPIMHYSEHEAALLAEKLKDDSKFSEAITVLLSWIERGEVNRRSANHFYSMVQSANSHVRRLMNEKATHEQEMEEAKENFKNALTGILTQFEQIVAVFNASTRQKAWDHFSKAQRKNIDIWRKHSEELRNAQSEQLMGIRREEEMEMSDDENCDSPTKKMRVDESALAAQAYALKEENDSLRWQLDAYRNEVELLKQEKEQLFRTEENLTKDQQVQFLQQTMQGMQQQLLTIQEELNNKKSELEQAKEEQSHTQALLKVLQEQLKGTKELVETNGHSHEDTNEINVLTVALVNQDRENNTEKRSQGLKSEKEALLIGIISTFLHVHPFGANIEYLWSYMQQLDSKMIKPVHDPTND", "length": 592, "header": "tr|A0AAA9TNB0-1|A0AAA9TTE7_BOVIN Computationally mapped isoform of Ecto-NOX disulfide-thiol exchanger 1 OS=Bos taurus OX=9913 GN=ENOX1 PE=3 SV=1 CANONICAL=A0AAA9TTE7-1" }, "locus": { "chromosome": "12", "start_pos": 13592607, "end_pos": 13358897, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000120987.1", "url": "https://www.ensembl.org/id/ENSBTAT00000120987.1" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000098493.1", "url": "https://www.ensembl.org/id/ENSBTAP00000098493.1" } ] } }, { "isoform_ac": "A0AAA9TTE7-1", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TTE7/entry", "sequence": { "sequence": "MMAADTLAGGILSRFAFPPAAADGLGSIAIDATQLNMSVTDPTAWATAMNNLGMVPVGLPGQQLVSDSICVPGFDPGLNMMTGITPINPMIPGLGLVPPPPPTEVAVVKEIIHCKSCTLFPQNPNLPPPSTRERPPGCKTVFVGGLPENATEEIIQEVFEQCGDITAIRKSKKNFCHIRFAEEFMVDKAIYLSGYRMRLGSSTDKKDSGRLHVDFAQARDDFYEWECKQRMRAREERHRRKLEEDRLRPPSPPPIMHYSEHEAALLAEKLKDDSKFSEAITVLLSWIERGEVNRRSANHFYSMVQSANSHVRRLMNEKATHEQEMEEAKENFKNALTGILTQFEQIVAVFNASTRQKAWDHFSKAQRKNIDIWRKHSEELRNAQSEQLMGIRREEEMEMSDDENCDSPTKKMRVDESALAAQAYALKEENDSLRWQLDAYRNEVELLKQEKEQLFRTEENLTKDQQVQFLQQTMQGMQQQLLTIQEELNNKKSELEQAKEEQSHTQALLKVLQEQLKGTKELVETNGHSHEDTNEINVLTVALVNQDRENNTEKRSQGLKSEKEALLIGIISTFLHVHPFGANIEYLWSYMQQLDSKISANEIEMLLMRLPRMFKQEFTGVGATLEKRWKLCAFEGIKTT", "length": 640, "header": "tr|A0AAA9TTE7-1|A0AAA9TTE7_BOVIN Isoform 1 of Ecto-NOX disulfide-thiol exchanger 1 OS=Bos taurus OX=9913 GN=ENOX1 PE=3 SV=1 CANONICAL=A0AAA9TTE7-1" }, "locus": { "chromosome": "12", "start_pos": 13592607, "end_pos": 13339818, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000105557.1", "url": "https://www.ensembl.org/id/ENSBTAT00000105557.1" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000101908.1", "url": "https://www.ensembl.org/id/ENSBTAP00000101908.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [ { "id": "bta:615969", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?bta:615969", "resource": "KEGG Pathway" } ], "orthologs": [], "go_annotation": { "categories": [ { "name": "Molecular Function", "total": 4, "go_terms": [ { "name": "NADH dehydrogenase activity", "id": "GO:0003954", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003954", "evidence": [ { "database": "UniProtKB", "id": "A0AAA9TTE7", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TTE7" } ], "pmid": "" }, { "name": "RNA binding", "id": "GO:0003723", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003723", "evidence": [ { "database": "UniProtKB", "id": "A0AAA9TTE7", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TTE7" } ], "pmid": "" }, { "name": "protein disulfide isomerase activity", "id": "GO:0003756", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003756", "evidence": [ { "database": "UniProtKB", "id": "A0AAA9TTE7", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TTE7" } ], "pmid": "" }, { "name": "oxidoreductase activity", "id": "GO:0016491", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016491", "evidence": [ { "database": "UniProtKB", "id": "A0AAA9TTE7", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TTE7" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 2, "go_terms": [ { "name": "extracellular region", "id": "GO:0005576", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005576", "evidence": [ { "database": "UniProtKB", "id": "A0AAA9TTE7", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TTE7" } ], "pmid": "" }, { "name": "external side of plasma membrane", "id": "GO:0009897", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0009897", "evidence": [ { "database": "UniProtKB", "id": "A0AAA9TTE7", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TTE7" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 1, "go_terms": [ { "name": "ultradian rhythm", "id": "GO:0007624", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007624", "evidence": [ { "database": "UniProtKB", "id": "A0AAA9TTE7", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TTE7" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 149, "end_pos": 151, "annotation": "n_glycosylation_sequon" }, { "start_pos": 351, "end_pos": 353, "annotation": "n_glycosylation_sequon" }, { "start_pos": 36, "end_pos": 38, "annotation": "n_glycosylation_sequon" }, { "start_pos": 430, "end_pos": 432, "annotation": "n_glycosylation_sequon" }, { "start_pos": 460, "end_pos": 462, "annotation": "n_glycosylation_sequon" }, { "start_pos": 550, "end_pos": 552, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A0AAA9TTE7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TTE7" }, { "id": "PS50102", "database": "PROSITE", "url": "https://prosite.expasy.org/PS50102" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "RRM", "eco_id": "ECO_0000259", "start_pos": 139, "end_pos": 218, "start_aa": "Lys", "end_aa": "Ala", "glycosite_overlap": [] } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 149, "end_pos": 151 }, { "start_pos": 351, "end_pos": 353 }, { "start_pos": 36, "end_pos": 38 }, { "start_pos": 430, "end_pos": 432 }, { "start_pos": 460, "end_pos": 462 }, { "start_pos": 550, "end_pos": 552 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ], "tool_support": { "graph_view": "yes" } }, { "uniprot_canonical_ac": "A0AAA9TST7-1", "uniprot_ac": "A0AAA9TST7", "uniprot_id": "A0AAA9TST7_BOVIN", "mass": { "chemical_mass": 43374.0, "monoisotopic_mass": 43374.0 }, "refseq": {}, "gene_names": [ { "name": "GPR68", "type": "recommended", "evidence": [ { "id": "A0AAA9TST7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TST7" } ] } ], "protein_names": [ { "name": "G protein-coupled receptor 68", "type": "synonym", "evidence": [ { "id": "A0AAA9TST7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TST7/entry#names_and_taxonomy" } ] } ], "function": [], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Bos taurus", "taxid": 9913, "evidence": [ { "database": "UniProtKB", "id": "A0AAA9TST7", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TST7" } ], "common_name": "Bovine", "glygen_name": "Bovine", "reference_species": "Bos taurus [9913]" } ], "gene": [ { "name": "GPR68", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TST7", "locus": { "chromosome": "21", "start_pos": 55998072, "end_pos": 56036571, "strand": "+", "evidence": [ { "database": "Ensembl Gene", "id": "ENSBTAG00000006738", "url": "https://www.ensembl.org/id/ENSBTAG00000006738" } ] } } ], "crossref": [ { "id": "A0AAA9TST7", "url": "https://alphafold.ebi.ac.uk/entry/A0AAA9TST7", "database": "AlphaFoldDB", "categories": [] }, { "id": "cd15367", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd15367", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "281799", "url": "https://www.ncbi.nlm.nih.gov/gene/281799", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR000276", "url": "https://www.ebi.ac.uk/interpro/entry/IPR000276", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR005389", "url": "https://www.ebi.ac.uk/interpro/entry/IPR005389", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR017452", "url": "https://www.ebi.ac.uk/interpro/entry/IPR017452", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "PTHR24234", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR24234", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR24234:SF5", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR24234:SF5", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00001", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00001", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "A0AAA9S2K7", "url": "https://www.uniprot.org/uniprotkb/A0AAA9S2K7", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0AAA9S2K7-1", "url": "https://www.uniprot.org/uniprotkb/A0AAA9S2K7-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0AAA9SDH4", "url": "https://www.uniprot.org/uniprotkb/A0AAA9SDH4", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0AAA9SDH4-1", "url": "https://www.uniprot.org/uniprotkb/A0AAA9SDH4-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0AAA9TST7", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TST7", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0AAA9TST7-1", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TST7-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MGGEAPAGPKMGNITADNTSMNCDIDHTIHQTLAPVVYVMVLVVGFPANCLSLYYGYLQIKARNELGVYLCNLTVADLFYICSLPFWLQYVLQHDHWSHDDLSCQVCGILLYENIYISVGFLCCISIDRYLAVAHPFRFHQFRTLKAAMGVSALIWVKELLTSIYFLMHEEVVEDADRHRVCFEHYPLEPRQRGINYYRFLVGFLFPICLLLASYRGILRAVRRSHGTQKSRKDQIQRLVLSTVVIFLACFLPYHVLLLVRSLWESSCDFAKGIFNAYHFSLLLTSFNCVADPVLYCFVSETTHRDLARLRGACLAFLTCARTGRAREAYPLGAPEASGKSEDPEVLTRLHPAFQTPHPPGMGGSPAEDWLQGSSLLKLPTQSC", "length": 384, "header": "tr|A0AAA9TST7-1|A0AAA9TST7_BOVIN Isoform 1 of G protein-coupled receptor 68 OS=Bos taurus OX=9913 GN=GPR68 PE=3 SV=1 CANONICAL=A0AAA9TST7-1" }, "isoforms": [ { "isoform_ac": "A0AAA9S2K7-1", "url": "https://www.uniprot.org/uniprotkb/A0AAA9S2K7/entry", "sequence": { "sequence": "MGGEAPAGPKMGNITADNTSMNCDIDHTIHQTLAPVVYVMVLVVGFPANCLSLYYGYLQIKARNELGVYLCNLTVADLFYICSLPFWLQYVLQHDHWSHDDLSCQVCGILLYENIYISVGFLCCISIDRYLAVAHPFRFHQFRTLKAAMGVSALIWVKELLTSIYFLMHEEVVEDADRHRVCFEHYPLEPRQRGINYYRFLVGFLFPICLLLASYRGILRAVRRSHGTQKSRKDQIQRLVLSTVVIFLACFLPYHVLLLVRSLWESSCDFAKGIFNAYHFSLLLTSFNCVADPVLYCFVSETTHRDLARLRGACLAFLTCARTGRAREAYPLGAPEASGKSEDPEVLTRLHPAFQTPHPPGMGGSPAGGLS", "length": 371, "header": "tr|A0AAA9S2K7-1|A0AAA9TST7_BOVIN Computationally mapped isoform of G protein-coupled receptor 68 OS=Bos taurus OX=9913 GN=GPR68 PE=3 SV=1 CANONICAL=A0AAA9TST7-1" }, "locus": { "chromosome": "21", "start_pos": 56001648, "end_pos": 56000536, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000114800.1", "url": "https://www.ensembl.org/id/ENSBTAT00000114800.1" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000083940.1", "url": "https://www.ensembl.org/id/ENSBTAP00000083940.1" } ] } }, { "isoform_ac": "A0AAA9SDH4-1", "url": "https://www.uniprot.org/uniprotkb/A0AAA9SDH4/entry", "sequence": { "sequence": "MGGEAPAGPKMGNITADNTSMNCDIDHTIHQTLAPVVYVMVLVVGFPANCLSLYYGYLQIKARNELGVYLCNLTVADLFYICSLPFWLQYVLQHDHWSHDDLSCQVCGILLYENIYISVGFLCCISIDRYLAVAHPFRFHQFRTLKAAMGVSALIWVKELLTSIYFLMHEEVVEDADRHRVCFEHYPLEPRQRGINYYRFLVGFLFPICLLLASYRGILRAVRRSHGTQKSRKDQIQRLVLSTVVIFLACFLPYHVLLLVRSLWESSCDFAKGIFNAYHFSLLLTSFNCVADPVLYCFVSETTHRDLARLRGACLAFLTCARTGRAREAYPLGAPEASGKSEDPEVLTRLHPAFQTPHPPGMGGSPAGSLV", "length": 371, "header": "tr|A0AAA9SDH4-1|A0AAA9TST7_BOVIN Computationally mapped isoform of G protein-coupled receptor 68 OS=Bos taurus OX=9913 GN=GPR68 PE=3 SV=1 CANONICAL=A0AAA9TST7-1" }, "locus": { "chromosome": "21", "start_pos": 56001648, "end_pos": 56000358, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000127702.1", "url": "https://www.ensembl.org/id/ENSBTAT00000127702.1" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000081611.1", "url": "https://www.ensembl.org/id/ENSBTAP00000081611.1" } ] } }, { "isoform_ac": "A0AAA9TST7-1", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TST7/entry", "sequence": { "sequence": "MGGEAPAGPKMGNITADNTSMNCDIDHTIHQTLAPVVYVMVLVVGFPANCLSLYYGYLQIKARNELGVYLCNLTVADLFYICSLPFWLQYVLQHDHWSHDDLSCQVCGILLYENIYISVGFLCCISIDRYLAVAHPFRFHQFRTLKAAMGVSALIWVKELLTSIYFLMHEEVVEDADRHRVCFEHYPLEPRQRGINYYRFLVGFLFPICLLLASYRGILRAVRRSHGTQKSRKDQIQRLVLSTVVIFLACFLPYHVLLLVRSLWESSCDFAKGIFNAYHFSLLLTSFNCVADPVLYCFVSETTHRDLARLRGACLAFLTCARTGRAREAYPLGAPEASGKSEDPEVLTRLHPAFQTPHPPGMGGSPAEDWLQGSSLLKLPTQSC", "length": 384, "header": "tr|A0AAA9TST7-1|A0AAA9TST7_BOVIN Isoform 1 of G protein-coupled receptor 68 OS=Bos taurus OX=9913 GN=GPR68 PE=3 SV=1 CANONICAL=A0AAA9TST7-1" }, "locus": { "chromosome": "21", "start_pos": 56001648, "end_pos": 55999277, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000130012.1", "url": "https://www.ensembl.org/id/ENSBTAT00000130012.1" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000101674.1", "url": "https://www.ensembl.org/id/ENSBTAP00000101674.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [], "orthologs": [], "go_annotation": { "categories": [ { "name": "Molecular Function", "total": 1, "go_terms": [ { "name": "G protein-coupled receptor activity", "id": "GO:0004930", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0004930", "evidence": [ { "database": "UniProtKB", "id": "A0AAA9TST7", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TST7" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 1, "go_terms": [ { "name": "plasma membrane", "id": "GO:0005886", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005886", "evidence": [ { "database": "UniProtKB", "id": "A0AAA9TST7", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TST7" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 4, "go_terms": [ { "name": "adenylate cyclase-activating G protein-coupled receptor signaling pathway", "id": "GO:0007189", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007189", "evidence": [ { "database": "UniProtKB", "id": "A0AAA9TST7", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TST7" } ], "pmid": "" }, { "name": "phospholipase C-activating G protein-coupled receptor signaling pathway", "id": "GO:0007200", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007200", "evidence": [ { "database": "UniProtKB", "id": "A0AAA9TST7", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TST7" } ], "pmid": "" }, { "name": "response to fluid shear stress", "id": "GO:0034405", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0034405", "evidence": [ { "database": "UniProtKB", "id": "A0AAA9TST7", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TST7" } ], "pmid": "" }, { "name": "cellular response to acidic pH", "id": "GO:0071468", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0071468", "evidence": [ { "database": "UniProtKB", "id": "A0AAA9TST7", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TST7" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 13, "end_pos": 15, "annotation": "n_glycosylation_sequon" }, { "start_pos": 18, "end_pos": 20, "annotation": "n_glycosylation_sequon" }, { "start_pos": 72, "end_pos": 74, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A0AAA9TST7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TST7" }, { "id": "PS50262", "database": "PROSITE", "url": "https://prosite.expasy.org/PS50262" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "G-protein coupled receptors family 1 profile", "eco_id": "ECO_0000259", "start_pos": 48, "end_pos": 296, "start_aa": "Ala", "end_aa": "Tyr", "glycosite_overlap": [] } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 13, "end_pos": 15 }, { "start_pos": 18, "end_pos": 20 }, { "start_pos": 72, "end_pos": 74 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ], "tool_support": { "graph_view": "yes" } }, { "uniprot_canonical_ac": "A0AAA9TVK6-1", "uniprot_ac": "A0AAA9TVK6", "uniprot_id": "A0AAA9TVK6_BOVIN", "mass": { "chemical_mass": 28535.0, "monoisotopic_mass": 28535.0 }, "refseq": {}, "gene_names": [ { "name": "LOC617648", "type": "recommended", "evidence": [ { "id": "A0AAA9TVK6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TVK6" } ] } ], "protein_names": [ { "name": "ASCH domain-containing protein", "type": "recommended", "evidence": [ { "id": "A0AAA9TVK6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TVK6/entry#names_and_taxonomy" } ] } ], "function": [], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Bos taurus", "taxid": 9913, "evidence": [ { "database": "UniProtKB", "id": "A0AAA9TVK6", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TVK6" } ], "common_name": "Bovine", "glygen_name": "Bovine", "reference_species": "Bos taurus [9913]" } ], "gene": [ { "name": "LOC617648", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TVK6", "locus": {} } ], "crossref": [ { "id": "A0AAA9TVK6", "url": "https://alphafold.ebi.ac.uk/entry/A0AAA9TVK6", "database": "AlphaFoldDB", "categories": [] }, { "id": "IPR015947", "url": "https://www.ebi.ac.uk/interpro/entry/IPR015947", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR033615", "url": "https://www.ebi.ac.uk/interpro/entry/IPR033615", "database": "InterPro", "categories": [ "Protein 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"UniProtKB", "categories": [ "Protein" ] }, { "id": "A0AAA9TVK6-1", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TVK6-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "GQLAPSPDSGPGGGLLSCLVAAARPSQKSARDSLYLQEGGTCLVCRRYLRAGVSRLWDQEPLPGGRTGPSGPLHGHSPRLLSFHPHEALGALGDEVRLSVLQKPYAGFILNGVKTLETRWRPVLRGHQHCTLAVHIARRDWEDAAWRELLEQRLGMSPAQIQALLRDGDKFGRGVIAGLVDIGDTLLCPENLDPEEVEELENQALLPDLRQKYLTVLTNPRWLLQPIPGRGGKDIFLVDIPQHLIPFGQEACPIWAFKR", "length": 259, "header": "tr|A0AAA9TVK6-1|A0AAA9TVK6_BOVIN Isoform 1 of ASCH domain-containing protein OS=Bos taurus OX=9913 GN=LOC617648 PE=4 SV=1 CANONICAL=A0AAA9TVK6-1" }, "isoforms": [ { "isoform_ac": "A0AAA9S331-1", "url": "https://www.uniprot.org/uniprotkb/A0AAA9S331/entry", "sequence": { "sequence": "MPHEALGALGDEVRLSVLQKPYAGFILNGVKTLETRWRPVLRGHQHCTLAVHIARRDWEDAAWRELLEQRLGMSPAQIQALLRDGDKFGRGVIAGLVDIGDTLLCPENLDPEEVEELENQALLPDLRQKYLTVLTNPRWLLQPIPGRGGKDIFLVDIPQHLIPFGQEACPIWAFKR", "length": 176, "header": "tr|A0AAA9S331-1|A0AAA9TVK6_BOVIN Computationally mapped isoform of ASCH domain-containing protein OS=Bos taurus OX=9913 GN=LOC617648 PE=4 SV=1 CANONICAL=A0AAA9TVK6-1" }, "locus": { "chromosome": "X", "start_pos": 35275787, "end_pos": 35270628, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000096509.1", "url": "https://www.ensembl.org/id/ENSBTAT00000096509.1" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000078160.1", "url": "https://www.ensembl.org/id/ENSBTAP00000078160.1" } ] } }, { "isoform_ac": "A0AAA9T4P0-1", "url": "https://www.uniprot.org/uniprotkb/A0AAA9T4P0/entry", "sequence": { "sequence": "MMMLSASQWPHEALGALGDEVRLSVLQKPYAGFILNGVKTLETRWRPVLRGHQHCTLAVHIARRDWEDAAWRELLEQRLGMSPAQIQALLRDGDKFGRGVIAGLVDIGDTLLCPENLDPEEVEELENQALLPDLRQKYLTVLTNPRWLLQPIPGRGGKDIFLVDIPQHLIPFGQEACPIWAFKR", "length": 184, "header": "tr|A0AAA9T4P0-1|A0AAA9TVK6_BOVIN Computationally mapped isoform of ASCH domain-containing protein OS=Bos taurus OX=9913 GN=LOC617648 PE=4 SV=1 CANONICAL=A0AAA9TVK6-1" }, "locus": { "chromosome": "X", "start_pos": 35274105, "end_pos": 35270628, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000100605.1", "url": "https://www.ensembl.org/id/ENSBTAT00000100605.1" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000093749.1", "url": "https://www.ensembl.org/id/ENSBTAP00000093749.1" } ] } }, { "isoform_ac": "A0AAA9TVK6-1", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TVK6/entry", "sequence": { "sequence": "GQLAPSPDSGPGGGLLSCLVAAARPSQKSARDSLYLQEGGTCLVCRRYLRAGVSRLWDQEPLPGGRTGPSGPLHGHSPRLLSFHPHEALGALGDEVRLSVLQKPYAGFILNGVKTLETRWRPVLRGHQHCTLAVHIARRDWEDAAWRELLEQRLGMSPAQIQALLRDGDKFGRGVIAGLVDIGDTLLCPENLDPEEVEELENQALLPDLRQKYLTVLTNPRWLLQPIPGRGGKDIFLVDIPQHLIPFGQEACPIWAFKR", "length": 259, "header": "tr|A0AAA9TVK6-1|A0AAA9TVK6_BOVIN Isoform 1 of ASCH domain-containing protein OS=Bos taurus OX=9913 GN=LOC617648 PE=4 SV=1 CANONICAL=A0AAA9TVK6-1" }, "locus": { "chromosome": "X", "start_pos": 35275266, "end_pos": 35270628, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000131190.1", "url": "https://www.ensembl.org/id/ENSBTAT00000131190.1" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000100612.1", "url": "https://www.ensembl.org/id/ENSBTAP00000100612.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [], "orthologs": [], "go_annotation": {}, "pro_annotation": [], "site_annotation": [], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": 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"publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ], "tool_support": { "graph_view": "yes" } }, { "uniprot_canonical_ac": "A0AAA9TTV1-1", "uniprot_ac": "A0AAA9TTV1", "uniprot_id": "A0AAA9TTV1_BOVIN", "mass": { "chemical_mass": 116022.0, "monoisotopic_mass": 116022.0 }, "refseq": { "ac": "XP_005205616", "name": "serine/threonine-protein kinase 31 isoform X1", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_005205616" }, "gene_names": [ { "name": "STK31", "type": "recommended", "evidence": [ { "id": "A0AAA9TTV1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TTV1" } ] }, { "name": "STK31", "type": "synonym", "evidence": [ { "id": "XP_005205616", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_005205616" } ] } ], "protein_names": [ { "name": "Serine/threonine kinase 31", "type": "synonym", "evidence": [ { "id": "A0AAA9TTV1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TTV1/entry#names_and_taxonomy" } ] }, { "name": "serine/threonine-protein kinase 31 isoform X1", "type": "synonym", "evidence": [ { "id": "XP_005205616", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_005205616" } ] } ], "function": [], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Bos taurus", "taxid": 9913, "evidence": [ { "database": "UniProtKB", "id": "A0AAA9TTV1", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TTV1" } ], "common_name": "Bovine", "glygen_name": "Bovine", "reference_species": "Bos taurus [9913]" } ], "gene": [ { "name": "STK31", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TTV1", "locus": { "chromosome": "4", "start_pos": 71959101, "end_pos": 72031364, "strand": "+", "evidence": [ { "database": "Ensembl Gene", "id": "ENSBTAG00000010609", "url": "https://www.ensembl.org/id/ENSBTAG00000010609" } ] } } ], "crossref": [ { "id": "A0AAA9TTV1", "url": "https://alphafold.ebi.ac.uk/entry/A0AAA9TTV1", "database": "AlphaFoldDB", "categories": [] }, { "id": "ENSBTAG00000010609", "url": "https://bgee.org/?page=gene&gene_id=ENSBTAG00000010609", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "cd20430", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd20430", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "132342094", "url": "https://www.ncbi.nlm.nih.gov/gene/132342094", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR000719", "url": "https://www.ebi.ac.uk/interpro/entry/IPR000719", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR002999", "url": "https://www.ebi.ac.uk/interpro/entry/IPR002999", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR011009", "url": "https://www.ebi.ac.uk/interpro/entry/IPR011009", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR035437", "url": "https://www.ebi.ac.uk/interpro/entry/IPR035437", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR047383", "url": "https://www.ebi.ac.uk/interpro/entry/IPR047383", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR052451", "url": "https://www.ebi.ac.uk/interpro/entry/IPR052451", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "bta:132342094", "url": "https://www.genome.jp/dbget-bin/www_bget?bta:132342094", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "E1BBF0", "url": "https://www.orthodb.org/?gene=E1BBF0", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR48008", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR48008", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR48008:SF6", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR48008:SF6", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00069", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00069", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF00567", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00567", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "XP_005205616", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_005205616", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0AAA9S3P2", "url": "https://www.uniprot.org/uniprotkb/A0AAA9S3P2", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0AAA9S3P2-1", "url": "https://www.uniprot.org/uniprotkb/A0AAA9S3P2-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0AAA9S440", "url": "https://www.uniprot.org/uniprotkb/A0AAA9S440", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0AAA9S440-1", "url": "https://www.uniprot.org/uniprotkb/A0AAA9S440-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0AAA9TTV1", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TTV1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0AAA9TTV1-1", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TTV1-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "E1BBF0", "url": "https://www.uniprot.org/uniprotkb/E1BBF0", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "E1BBF0-1", "url": "https://www.uniprot.org/uniprotkb/E1BBF0-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MLAQQRARKRRLETQWPEHVSFAGIVQMEEDKHCNKVEDVVGSHVEDAVTFWAQSINRNKDIMKIGCSLSEVCPLANSVFGNLDPKKIYGGLFSEDKCWYRCQVLKVINDEKCLVRYIDYGNTEILNRSDIVEIPLDLQFSSVAKKYRLWGLQIPSSQEVTQFDQGRTFLGSLIFEKEIKMRIKATYQDGTIIAQAEYGNVDIGEEVAKKGFAEKCRLTSSTNICEEKKSDPGQLVLRNLKSPIPLWGHRSSQSNFTRPKGRLSGRMCLDLKNENDAGNNVTFPKENLAVGDFNLGSNVSLAKIKQDQKLIEENEKLKTEKEVLLERCKALELKVEQTAQELQQEKATTMDLTKRLESTVKTCIGTRMKNLAAKVEILKEIRRVSISVRFGNDLSDAIQVLDEDCFTIPASLNELELIWAEYNLAQEKIQTCENVNEGNILIAERNEVQQKLYMAVEVFILEVDELSLNKRLKTLQDLSASLEAVYGQAKEGINSEEILEKFNDWRCNKREEFTSVRSETETCIQRLIAWFQNTLKAFDLSVDKSLISDDTIDNIDEILENTESGVCKELEISLIEQGDADKEIILKTCSQVLQKIRSEESLIATVQSKYKDSVEFKKQIIECLNKSPSVDHLLSIKKTLKSLKARLRWKLVEKNNLEESDDHDGSEIEKIKQEITQLRNSVFEGIYHEQEEYAKLSSLVQKWFPELPLLHPEIGLLKYMNSGGLLTMSLERDLLDAEPMKELSSKRPLICSEVNGQIILLKGYSVDVDTEARVIQRAAAYHTAWREAKGESGLLPLIFLFLCKSDPMAYLMVPYYPRANLNAVQSTMPLTSEEVLKVMKGVAQGLHTLHKADIVHGSLHQNNVFALNRQHGIVGDFDFTKSVSQRTSVNMMVGDLSLLSPELKMGKPASPSSDLYAYGCLLLWLSVQNQEFETNEDGIPKMDQFHLDDNVKSLLCSLICCRSSMTAEQVLNADCFLLPKGKSMPNSEKDTEYIPKKEEEELKVKNLDKDKEKTRNGEASFD", "length": 1022, "header": "tr|A0AAA9TTV1-1|A0AAA9TTV1_BOVIN Isoform 1 of Serine/threonine kinase 31 OS=Bos taurus OX=9913 GN=STK31 PE=4 SV=1 CANONICAL=A0AAA9TTV1-1" }, "isoforms": [ { "isoform_ac": "A0AAA9S3P2-1", "url": "https://www.uniprot.org/uniprotkb/A0AAA9S3P2/entry", "sequence": { "sequence": "MLAQQRARKRRLETQWPEHVSFAGIVQMEEDKHCNKVEDVVGSHVEDAVTFWAQSINRNKDIMKIGCSLSEVCPLANSVFGNLDPKKIYGGLFSEDKCWYRCQVLKVINDEKCLVRYIDYGNTEILNRSDIVEIPLDLQFSSVAKKYRLWGLQIPSSQEVTQFDQGRTFLGSLIFEKEIKMRIKATYQDGTIIAQAEYGNVDIGEEVAKKGFAEKCRLTSSTNICEEKKSDPGQLVLRNLKSPIPLWGHRSSQSNFTRPKGRLSGRMCLDLKNENDAGNNVTFPKENLAVGDFNLGSNVSLAKIKQDQKLIEENEKLKTEKEVLLERCKALELKVEQTAQELQQEKATTMDLTKRLESTVKTCIGTRMKNLAAKVEILKEIRRVSISVRFGNDLSDAIQVLDEDCFTIPASLNELELIWAEYNLAQEKIQTCENVDLSASLEAVYGQAKEGINSEEILEKFNDWRCNKREEFTSVRSETETCIQRLIAWFQNTLKAFDLSVDKSLISDDTIDNIDEILENTESGVCKELEISLIEQGDADKEIILKTCSQVLQKIRSEESLIATVQSKYKDSVEFKKQIIECLNKSPSVDHLLSIKKTLKSLKARLRWKLVEKNNLEESDDHDGSEIEKIKQEITQLRNSVFEGIYHEQEEYAKLSSLVQKWFPELPLLHPEIGLLKYMNSGGLLTMSLERDLLDAEPMKELSSKRPLICSEVNGQIILLKGYSVDVDTEARVIQRAAAYHTAWREAKGESGLLPLIFLFLCKSDPMAYLMVPYYPRANLNAVQSTMPLTSEEVLKVMKGVAQGLHTLHKADIVHGSLHQNNVFALNRQHGIVGDFDFTKSVSQRTSVNMMVGDLSLLSPELKMGKPASPSSDLYAYGCLLLWLSVQNQEFETNEDGIPKMDQFHLDDNVKSLLCSLICCRSSMTAEQVLNADCFLLPKGKSMPNSEKDTEYIPKKEEEELKVKNLDKDKEKTRNGEASFD", "length": 981, "header": "tr|A0AAA9S3P2-1|A0AAA9TTV1_BOVIN Computationally mapped isoform of Serine/threonine kinase 31 OS=Bos taurus OX=9913 GN=STK31 PE=4 SV=1 CANONICAL=A0AAA9TTV1-1" }, "locus": { "chromosome": "4", "start_pos": 72031165, "end_pos": 71959260, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000125848.1", "url": "https://www.ensembl.org/id/ENSBTAT00000125848.1" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000077886.1", "url": "https://www.ensembl.org/id/ENSBTAP00000077886.1" } ] } }, { "isoform_ac": "A0AAA9S440-1", "url": "https://www.uniprot.org/uniprotkb/A0AAA9S440/entry", "sequence": { "sequence": "MRIGSAVCFAGIVQMEEDKHCNKVEDVVGSHVEDAVTFWAQSINRNKDIMKIGCSLSEVCPLANSVFGNLDPKKIYGGLFSEDKCWYRCQVLKVINDEKCLVRYIDYGNTEILNRSDIVEIPLDLQFSSVAKKYRLWGLQIPSSQEVTQFDQGRTFLGSLIFEKEIKMRIKATYQDGTIIAQAEYGNVDIGEEVAKKGFAEKCRLTSSTNICEEKKSDPGQLVLRNLKSPIPLWGHRSSQSNFTRPKGRLSGRMCLDLKNENDAGNNVTFPKENLAVGDFNLGSNVSLAKIKQDQKLIEENEKLKTEKEVLLERCKALELKVEQTAQELQQEKATTMDLTKRLESTVKTCIGTRMKNLAAKVEILKEIRRVSISVRFGNDLSDAIQVLDEDCFTIPASLNELELIWAEYNLAQEKIQTCENVNEGNILIAERNEVQQKLYMAVEVFILEVDELSLNKRLKTLQDLSASLEAVYGQAKEGINSEEILEKFNDWRCNKREEFTSVRSETETCIQRLIAWFQNTLKAFDLSVDKSLISDDTIDNIDEILENTESGVCKELEISLIEQGDADKEIILKTCSQVLQKIRSEESLIATVQSKYKDSVEFKKQIIECLNKSPSVDHLLSIKKTLKSLKARLRWKLVEKNNLEESDDHDGSEIEKIKQEITQLRNSVFEGIYHEQEEYAKLSSLVQKWFPELPLLHPEIGLLKYMNSGGLLTMSLERDLLDAEPMKELSSKRPLICSEVNGQIILLKGYSVDVDTEARVIQRAAAYHTAWREAKGESGLLPLIFLFLCKSDPMAYLMVPYYPRANLNAVQSTMPLTSEEVLKVMKGVAQGLHTLHKADIVHGSLHQNNVFALNRQHGIVGDFDFTKSVSQRTSVNMMVGDLSLLSPELKMGKPASPSSDLYAYGCLLLWLSVQNQEFETNEDGIPKMDQFHLDDNVKSLLCSLICCRSSMTAEQVLNADCFLLPKGKSMPNSEKDTEYIPKKEEEELKVKNLDKDKEKTRNGEASFD", "length": 1009, "header": "tr|A0AAA9S440-1|A0AAA9TTV1_BOVIN Computationally mapped isoform of Serine/threonine kinase 31 OS=Bos taurus OX=9913 GN=STK31 PE=4 SV=1 CANONICAL=A0AAA9TTV1-1" }, "locus": { "chromosome": "4", "start_pos": 72030666, "end_pos": 71959260, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000126641.1", "url": "https://www.ensembl.org/id/ENSBTAT00000126641.1" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000078564.1", "url": "https://www.ensembl.org/id/ENSBTAP00000078564.1" } ] } }, { "isoform_ac": "A0AAA9TTV1-1", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TTV1/entry", "sequence": { "sequence": "MLAQQRARKRRLETQWPEHVSFAGIVQMEEDKHCNKVEDVVGSHVEDAVTFWAQSINRNKDIMKIGCSLSEVCPLANSVFGNLDPKKIYGGLFSEDKCWYRCQVLKVINDEKCLVRYIDYGNTEILNRSDIVEIPLDLQFSSVAKKYRLWGLQIPSSQEVTQFDQGRTFLGSLIFEKEIKMRIKATYQDGTIIAQAEYGNVDIGEEVAKKGFAEKCRLTSSTNICEEKKSDPGQLVLRNLKSPIPLWGHRSSQSNFTRPKGRLSGRMCLDLKNENDAGNNVTFPKENLAVGDFNLGSNVSLAKIKQDQKLIEENEKLKTEKEVLLERCKALELKVEQTAQELQQEKATTMDLTKRLESTVKTCIGTRMKNLAAKVEILKEIRRVSISVRFGNDLSDAIQVLDEDCFTIPASLNELELIWAEYNLAQEKIQTCENVNEGNILIAERNEVQQKLYMAVEVFILEVDELSLNKRLKTLQDLSASLEAVYGQAKEGINSEEILEKFNDWRCNKREEFTSVRSETETCIQRLIAWFQNTLKAFDLSVDKSLISDDTIDNIDEILENTESGVCKELEISLIEQGDADKEIILKTCSQVLQKIRSEESLIATVQSKYKDSVEFKKQIIECLNKSPSVDHLLSIKKTLKSLKARLRWKLVEKNNLEESDDHDGSEIEKIKQEITQLRNSVFEGIYHEQEEYAKLSSLVQKWFPELPLLHPEIGLLKYMNSGGLLTMSLERDLLDAEPMKELSSKRPLICSEVNGQIILLKGYSVDVDTEARVIQRAAAYHTAWREAKGESGLLPLIFLFLCKSDPMAYLMVPYYPRANLNAVQSTMPLTSEEVLKVMKGVAQGLHTLHKADIVHGSLHQNNVFALNRQHGIVGDFDFTKSVSQRTSVNMMVGDLSLLSPELKMGKPASPSSDLYAYGCLLLWLSVQNQEFETNEDGIPKMDQFHLDDNVKSLLCSLICCRSSMTAEQVLNADCFLLPKGKSMPNSEKDTEYIPKKEEEELKVKNLDKDKEKTRNGEASFD", "length": 1022, "header": "tr|A0AAA9TTV1-1|A0AAA9TTV1_BOVIN Isoform 1 of Serine/threonine kinase 31 OS=Bos taurus OX=9913 GN=STK31 PE=4 SV=1 CANONICAL=A0AAA9TTV1-1" }, "locus": { "chromosome": "4", "start_pos": 72031165, "end_pos": 71959260, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000093267.1", "url": "https://www.ensembl.org/id/ENSBTAT00000093267.1" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000100806.1", "url": "https://www.ensembl.org/id/ENSBTAP00000100806.1" } ] } }, { "isoform_ac": "E1BBF0-1", "url": "https://www.uniprot.org/uniprotkb/E1BBF0/entry", "sequence": { "sequence": "MEEDKHCNKVEDVVGSHVEDAVTFWAQSINRNKDIMKIGCSLSEVCPLANSVFGNLDPKKIYGGLFSEDKCWYRCQVLKVINDEKCLVRYIDYGNTEILNRSDIVEIPLDLQFSSVAKKYRLWGLQIPSSQEVTQFDQGRTFLGSLIFEKEIKMRIKATYQDGTIIAQAEYGNVDIGEEVAKKGFAEKCRLTSSTNICEEKKSDPGQLVLRNLKSPIPLWGHRSSQSNFTRPKGRLSGRMCLDLKNENDAGNNVTFPKENLAVGDFNLGSNVSLAKIKQDQKLIEENEKLKTEKEVLLERCKALELKVEQTAQELQQEKATTMDLTKRLESTVKTCIGTRMKNLAAKVEILKEIRRVSISVRFGNDLSDAIQVLDEDCFTIPASLNELELIWAEYNLAQEKIQTCENVNEGNILIAERNEVQQKLYMAVEVFILEVDELSLNKRLKTLQDLSASLEAVYGQAKEGINSEEILEKFNDWRCNKREEFTSVRSETETCIQRLIAWFQNTLKAFDLSVDKSLISDDTIDNIDEILENTESGVCKELEISLIEQGDADKEIILKTCSQVLQKIRSEESLIATVQSKYKDSVEFKKQIIECLNKSPSVDHLLSIKKTLKSLKARLRWKLVEKNNLEESDDHDGSEIEKIKQEITQLRNSVFEGIYHEQEEYAKLSSLVQKWFPELPLLHPEIGLLKYMNSGGLLTMSLERDLLDAEPMKELSSKRPLICSEVNGQIILLKGYSVDVDTEARVIQRAAAYHTAWREAKGESGLLPLIFLFLCKSDPMAYLMVPYYPRANLNAVQSTMPLTSEEVLKVMKGVAQGLHTLHKADIVHGSLHQNNVFALNRQHGIVGDFDFTKSVSQRTSVNMMVGDLSLLSPELKMGKPASPSSDLYAYGCLLLWLSVQNQEFETNEDGIPKMDQFHLDDNVKSLLCSLICCRSSMTAEQVLNADCFLLPKGKSMPNSEKDTEYIPKKEEEELKVKNLDKDKEKTRNGEASFD", "length": 995, "header": "tr|E1BBF0-1|E1BBF0_BOVIN Computationally mapped isoform of Serine/threonine kinase 31 OS=Bos taurus OX=9913 GN=STK31 PE=4 SV=4 CANONICAL=A0AAA9TTV1-1" }, "locus": { "chromosome": "4", "start_pos": 72028935, "end_pos": 71959260, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000014042.7", "url": "https://www.ensembl.org/id/ENSBTAT00000014042.7" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000014042.7", "url": "https://www.ensembl.org/id/ENSBTAP00000014042.7" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [ { "id": "bta:132342094", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?bta:132342094", "resource": "KEGG Pathway" } ], "orthologs": [], "go_annotation": { "categories": [ { "name": "Molecular Function", "total": 3, "go_terms": [ { "name": "protein kinase activity", "id": "GO:0004672", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0004672", "evidence": [ { "database": "UniProtKB", "id": "A0AAA9TTV1", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TTV1" } ], "pmid": "" }, { "name": "ATP binding", "id": "GO:0005524", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005524", "evidence": [ { "database": "UniProtKB", "id": "A0AAA9TTV1", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TTV1" } ], "pmid": "" }, { "name": "RNA endonuclease activity", "id": "GO:0004521", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0004521", "evidence": [ { "database": "UniProtKB", "id": "A0AAA9TTV1", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TTV1" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 1, "go_terms": [ { "name": "acrosomal vesicle", "id": "GO:0001669", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0001669", "evidence": [ { "database": "UniProtKB", "id": "A0AAA9TTV1", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TTV1" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 1, "go_terms": [ { "name": "RNA catabolic process", "id": "GO:0006401", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006401", "evidence": [ { "database": "UniProtKB", "id": "A0AAA9TTV1", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TTV1" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 127, "end_pos": 129, "annotation": "n_glycosylation_sequon" }, { "start_pos": 255, "end_pos": 257, "annotation": "n_glycosylation_sequon" }, { "start_pos": 280, "end_pos": 282, "annotation": "n_glycosylation_sequon" }, { "start_pos": 298, "end_pos": 300, "annotation": "n_glycosylation_sequon" }, { "start_pos": 625, "end_pos": 627, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A0AAA9TTV1", "database": "UniProtKB", "url": 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Directly and specifically regulates the adapter protein 3 (AP-3)-dependent trafficking of proteins in the endosomal-lysosomal system.", "evidence": [ { "database": "UniProtKB", "id": "A0A3Q1LQ31", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1LQ31#function" }, { "database": "UniProtKB", "id": "ARBA00060143", "url": "https://www.uniprot.org/uniprotkb/ARBA00060143#function" }, { "database": "UniProtKB", "id": "F1MGL2", "url": "https://www.uniprot.org/uniprotkb/F1MGL2#function" }, { "database": "UniProtKB", "id": "A0AAA9S554", "url": "https://www.uniprot.org/uniprotkb/A0AAA9S554#function" }, { "database": "UniProtKB", "id": "A0AAA9TUE2", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TUE2#function" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Bos taurus", "taxid": 9913, "evidence": [ { "database": "UniProtKB", "id": "A0AAA9TUE2", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TUE2" } ], "common_name": 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] }, { "id": "cd08836", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd08836", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "cd08853", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd08853", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "522241", "url": "https://www.ncbi.nlm.nih.gov/gene/522241", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR001164", "url": "https://www.ebi.ac.uk/interpro/entry/IPR001164", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR001806", "url": "https://www.ebi.ac.uk/interpro/entry/IPR001806", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR001849", "url": "https://www.ebi.ac.uk/interpro/entry/IPR001849", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR002110", "url": "https://www.ebi.ac.uk/interpro/entry/IPR002110", "database": 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"http://www.pantherdb.org/panther/family.do?clsAccession=PTHR45819", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR45819:SF1", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR45819:SF1", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00023", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00023", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF00071", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00071", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF00169", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00169", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF01412", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF01412", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF12796", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF12796", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "XP_059741216", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_059741216", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A3Q1LQ31", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1LQ31", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A3Q1LQ31-1", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1LQ31-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A3Q1M1U8", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1M1U8", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A3Q1M1U8-1", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1M1U8-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A3Q1MPJ8", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1MPJ8", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A3Q1MPJ8-1", "url": 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"MYLLDGSGEPASPPADAMPRGPPPRKTVYRISVTMVRKEQLGAPGPGGPDTRPTRRPRTARSPDAPGRLVEEAAGAEDPEDRRPPRAWDFRTFRTRSTGQLELGRLRPCARGPELEDRTGRPRAMEEEVEEGSGSPASGSPDVEGARAAPLRRSLSFRHWSRPEAPRGRALGRGRRYSSSGSLAWAPGGEEVADPGAALEPAVSGQPASEKRNTLDVGEVLSKNDALSDLERWERSKSKNRTLDNSDLQRLERARAAAAAAGHGTASEHRLLRFFSGIFARKEGAPGGGPSPRSGASRSRGYFSSLRRAPADAHSSSAESIDGSPRRDAFVNSQEWTLSRSVPELKVGIVGNLASGKSALVHRYLTGTYVQEESPEGGRFKKEIVVDGQSYLLLIRDEGGPPEAQFAMWVDAVIFVFSLEDEISFQTVYHYYSRMASYRNTSEIPLVLVGTQDAISSTNPRVIDDARARKLSSDLKRCTYYETCATYGLNVERVFQDVAQKIVATRKKQQLSIGPCKSLPNSPSHSSVCSAQVSAVHISQTSNGGGSLSDYSSSVPSTPSTSQKELRIDVPPAANTPTPVRKQSKRRSNLFTSRKGSDPDKEKKGLESRADSIGSGRAIPIKQGMLLKRSGKSLNKEWKKKYVTLCDNGVLTYHPSLHDYMQNVHGKEIDLLRTTVKVPGKRPPRATSACAPISSPKTNGLSKDMSSLHISPNSGSVASAPGSQMASGVSLGSFNSRADGMQQRSYSVSSADQWSEATVIANSAISSDTGLGDPLCSSPSISSTASPKLDPPPSPHANRKKHRRKKSTSNFKADGLSGTADEQEENFEFIIVSLTGQTWHFEATTYEERDAWVQAIESQILASLQSCESSKNKSRLTSQSEAMALQSIRNIRGNSHCVDCETQNPNWASLNLGALMCIECSGIHRNLGTHLSRVRSLDLDDWPIELIKVMSSIGNELANSVWEESTQGRTKPSLDSTREEKERWIRAKYEQKLFLAPLPCMELSLGQHLLRATADEDLRTVILLLAHGSRDEVNETCGEADGRTALHLACRKGNVVLAQLLIWYGVDVMARDAHGNTALAYARQASSQECTEVLLQYGCPDERFALMATPNLSRKNTNRNNSGGRVPTVI", "length": 1130, "header": "tr|A0AAA9TUE2-1|A0AAA9TUE2_BOVIN Isoform 1 of Arf-GAP with GTPase, ANK repeat and PH domain-containing protein 1 OS=Bos taurus OX=9913 GN=AGAP1 PE=3 SV=1 CANONICAL=A0AAA9TUE2-1" }, "isoforms": [ { "isoform_ac": "A0A3Q1LQ31-1", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1LQ31/entry", "sequence": { "sequence": "MNYQQQLANSAAIRAEIQRFESVHPNIYSIYELLERVEEPVLQNQIREHVIAIEDAFVNSQEWTLSRSVPELKVGIVGNLASGKSALVHRYLTGTYVQEESPEGGRFKKEIVVDGQSYLLLIRDEGGPPEAQFAMWVDAVIFVFSLEDEISFQTVYHYYSRMASYRNTSEIPLVLVGTQDAISSTNPRVIDDARARKLSSDLKRCTYYETCATYGLNVERVFQDVAQKIVATRKKQQLSIGPCKSLPNSPSHSSVCSAQVSAVHISQTSNGGGSLSDYSSSVPSTPSTSQKELRIDVPPAANTPTPVRKQSKRRSNLFTSRKGSDPDKEKKGLESRADSIGSGRAIPIKQGMLLKRSGKSLNKEWKKKYVTLCDNGVLTYHPSLHDYMQNVHGKEIDLLRTTVKVPGKRPPRATSACAPISSPKTNGLSKDMSSLHISPNSGSVASAPGSQMASGVSLGSFNSRADGMQQRSYSVSSADQWSEATVIANSAISSDTGLGDPLCSSPSISSTASPKLDPPPSPHANRKKHRRKKSTSNFKADGLSGTADEQEENFEFIIVSLTGQTWHFEATTYEERDAWVQAIESQILASLQSCESSKNKSRLTSQSEAMALQSIRNIRGNSHCVDCETQNPNWASLNLGALMCIECSGIHRNLGTHLSRVRSLDLDDWPIELIKVMSSIGNELANSVWEESTQGRTKPSLDSTREEKERWIRAKYEQKLFLAPLPCMELSLGQHLLRATADEDLRTVILLLAHGSRDEVNETCGEADGRTALHLACRKGNVVLAQLLIWAYAMQLEWGKERENITELLLRSPLILHGSYLHTSGVLGQGSSPHSKDGRKLD", "length": 842, "header": "tr|A0A3Q1LQ31-1|A0A3Q1LQ31_BOVIN Computationally mapped isoform of ArfGAP with GTPase domain, ankyrin repeat and PH domain 1 OS=Bos taurus OX=9913 GN=AGAP1 PE=3 SV=2 CANONICAL=A0AAA9TUE2-1" }, "locus": { "chromosome": "3", "start_pos": 115603171, "end_pos": 115044779, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000082896.2", "url": "https://www.ensembl.org/id/ENSBTAT00000082896.2" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000059079.2", "url": "https://www.ensembl.org/id/ENSBTAP00000059079.2" } ] } }, { "isoform_ac": "A0A3Q1M1U8-1", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1M1U8/entry", "sequence": { "sequence": "MNYQQQLANSAAIRAEIQRFESVHPNIYSIYELLERVEEPVLQNQIREHVIAIEDAFVNSQEWTLSRSVPELKVGIVGNLASGKSALVHRYLTGTYVQEESPEDMDAGGRFKKEIVVDGQSYLLLIRDEGGPPEAQFAMWVDAVIFVFSLEDEISFQTVYHYYSRMASYRNTSEIPLVLVGTQDAISSTNPRVIDDARARKLSSDLKRCTYYETCATYGLNVERVFQDVAQKIVATRKKQQLSIGPCKSLPNSPSHSSVCSAQVSAVHISQTSNGGGSLSDYSSSVPSTPSTSQKELRIDVPPAANTPTPVRKQSKRRSNLFTSRKGSDPDKEKKGLESRADSIGSGRAIPIKQGMLLKRSGKSLNKEWKKKYVTLCDNGVLTYHPSLHDYMQNVHGKEIDLLRTTVKVPGKRPPRATSACAPISSPKTNGLSKDMSSLHISPNSGSVASAPGSQMASGVSLGSFNSRADGMQQRSYSVSSADQWSEATVIANSAISSDTGLGDPLCSSPSISSTASPKLDPPPSPHANRKKHRRKKSTSNFKADGLSGTADAKRKAWKLNRVGSLRNIYSSSTNTEEQEENFEFIIVSLTGQTWHFEATTYEERDAWVQAIESQILASLQSCESSKNKSRLTSQSEAMALQSIRNIRGNSHCVDCETQNPNWASLNLGALMCIECSGIHRNLGTHLSRVRSLDLDDWPIELIKVMSSIGNELANSVWEESTQGRTKPSLDSTREEKERWIRAKYEQKLFLAPLPCMELSLGQHLLRATADEDLRTVILLLAHGSRDEVNETCGEADGRTALHLACRKGNVVLAQLLIWYGVDVMARDAHGNTALAYARQASSQECTEVLLQYGCPDERFALMATPNLSRKNTNRNNSGGRVPTVI", "length": 886, "header": "tr|A0A3Q1M1U8-1|A0A3Q1M1U8_BOVIN Computationally mapped isoform of Arf-GAP with GTPase, ANK repeat and PH domain-containing protein 1 OS=Bos taurus OX=9913 GN=AGAP1 PE=3 SV=2 CANONICAL=A0AAA9TUE2-1" }, "locus": { "chromosome": "3", "start_pos": 115604933, "end_pos": 115044779, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000081985.2", "url": "https://www.ensembl.org/id/ENSBTAT00000081985.2" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000062041.2", "url": "https://www.ensembl.org/id/ENSBTAP00000062041.2" } ] } }, { "isoform_ac": "A0A3Q1MPJ8-1", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1MPJ8/entry", "sequence": { "sequence": "MNYQQQLANSAAIRAEIQRFESVHPNIYSIYELLERVEEPVLQNQIREHVIAIEDAFVNSQEWTLSRSVPELKVGIVGNLASGKSALVHRYLTGTYVQEESPEGGRFKKEIVVDGQSYLLLIRDEGGPPEAQFAMWVDAVIFVFSLEDEISFQTVYHYYSRMASYRNTSEIPLVLVGTQDAISSTNPRVIDDARARKLSSDLKRCTYYETCATYGLNVERVFQDVAQKIVATRKKQQLSIGPCKSLPNSPSHSSVCSAQVSAVHISQTSNGGGSLSDYSSSVPSTPSTSQKELRIDVPPAANTPTPVRKQSKRRSNLFTSRKGSDPDKEKKGLESRADSIGSGRAIPIKQGMLLKRSGKSLNKEWKKKYVTLCDNGVLTYHPSLHDYMQNVHGKEIDLLRTTVKVPGKRPPRATSACAPISSPKTNGLSKDMSSLHISPNSGSVASAPGSQMASGVSLGSFNSRADGMQQRSYSVSSADQWSEATVIANSAISSEQEENFEFIIVSLTGQTWHFEATTYEERDAWVQAIESQILASLQSCESSKNKSRLTSQSEAMALQSIRNIRGNSHCVDCETQNPNWASLNLGALMCIECSGIHRNLGTHLSRVRSLDLDDWPIELIKVMSSIGNELANSVWEESTQGRTKPSLDSTREEKERWIRAKYEQKLFLAPLPCMELSLGQHLLRATADEDLRTVILLLAHGSRDEVNETCGEADGRTALHLACRKGNVVLAQLLIWYGVDVMARDAHGNTALAYARQASSQECTEVLLQYGCPDERFALMATPNLSRKNTNRNNSGGRVPTVI", "length": 803, "header": "tr|A0A3Q1MPJ8-1|A0A3Q1MPJ8_BOVIN Computationally mapped isoform of Arf-GAP with GTPase, ANK repeat and PH domain-containing protein 1 OS=Bos taurus OX=9913 GN=AGAP1 PE=3 SV=2 CANONICAL=A0AAA9TUE2-1" }, "locus": { "chromosome": "3", "start_pos": 115604933, "end_pos": 115044779, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000066786.2", "url": "https://www.ensembl.org/id/ENSBTAT00000066786.2" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000073395.2", "url": "https://www.ensembl.org/id/ENSBTAP00000073395.2" } ] } }, { "isoform_ac": "A0AAA9S554-1", "url": "https://www.uniprot.org/uniprotkb/A0AAA9S554/entry", "sequence": { "sequence": "MYLLDGSGEPASPPADAMPRGPPPRKTVYRISVTMVRKEQLGAPGPGGPDTRPTRRPRTARSPDAPGRLVEEAAGAEDPEDRRPPRAWDFRTFRTRSTGQLELGRLRPCARGPELEDRTGRPRAMEEEVEEGSGSPASGSPDVEGARAAPLRRSLSFRHWSRPEAPRGRALGRGRRYSSSGSLAWAPGGEEVADPGAALEPAVSGQPASEKRNTLDVGEVLSKNDALSDLERWERSKSKNRTLDNSDLQRLERARAAAAAAGHGTASEHRLLRFFSGIFARKEGAPGGGPSPRSGASRSRGYFSSLRRAPADAHSSSAESIDGSPRRDAFVNSQEWTLSRSVPELKVGIVGNLASGKSALVHRYLTGTYVQEESPEGGRFKKEIVVDGQSYLLLIRDEGGPPEAQFAMWVDAVIFVFSLEDEISFQTVYHYYSRMASYRNTSEIPLVLVGTQDAISSTNPRVIDDARARKLSSDLKRCTYYETCATYGLNVERVFQDVAQKIVATRKKQQLSIGPCKSLPNSPSHSSVCSAQVSAVHISQTSNGGGSLSDYSSSVPSTPSTSQKELRIDVPPAANTPTPVRKQSKRRSNLFTSRKGSDPDKEKKGLESRADSIGSGRAIPIKQGMLLKRSGKSLNKEWKKKYVTLCDNGVLTYHPSLHDYMQNVHGKEIDLLRTTVKVPGKRPPRATSACAPISSPKTNGLSKDMSSLHISPNSDTGLGDPLCSSPSISSTASPKLDPPPSPHANRKKHRRKKSTSNFKADGLSGTADEQEENFEFIIVSLTGQTWHFEATTYEERDAWVQAIESQILASLQSCESSKNKSRLTSQSEAMALQSIRNIRGNSHCVDCETQNPNWASLNLGALMCIECSGIHRNLGTHLSRVRSLDLDDWPIELIKVMSSIGNELANSVWEESTQGRTKPSLDSTREEKERWIRAKYEQKLFLAPLPCMELSLGQHLLRATADEDLRTVILLLAHGSRDEVNETCGEADGRTALHLACRKGNVVLAQLLIWYGVDVMARDAHGNTALAYARQASSQECTEVLLQYGCPDERFALMATPNLSRKNTNRNNSGGRVPTVI", "length": 1077, "header": "tr|A0AAA9S554-1|A0AAA9TUE2_BOVIN Computationally mapped isoform of Arf-GAP with GTPase, ANK repeat and PH domain-containing protein 1 OS=Bos taurus OX=9913 GN=AGAP1 PE=3 SV=1 CANONICAL=A0AAA9TUE2-1" }, "locus": { "chromosome": "3", "start_pos": 115604933, "end_pos": 115201466, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000134902.1", "url": "https://www.ensembl.org/id/ENSBTAT00000134902.1" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000078364.1", "url": "https://www.ensembl.org/id/ENSBTAP00000078364.1" } ] } }, { "isoform_ac": "A0AAA9TUE2-1", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TUE2/entry", "sequence": { "sequence": "MYLLDGSGEPASPPADAMPRGPPPRKTVYRISVTMVRKEQLGAPGPGGPDTRPTRRPRTARSPDAPGRLVEEAAGAEDPEDRRPPRAWDFRTFRTRSTGQLELGRLRPCARGPELEDRTGRPRAMEEEVEEGSGSPASGSPDVEGARAAPLRRSLSFRHWSRPEAPRGRALGRGRRYSSSGSLAWAPGGEEVADPGAALEPAVSGQPASEKRNTLDVGEVLSKNDALSDLERWERSKSKNRTLDNSDLQRLERARAAAAAAGHGTASEHRLLRFFSGIFARKEGAPGGGPSPRSGASRSRGYFSSLRRAPADAHSSSAESIDGSPRRDAFVNSQEWTLSRSVPELKVGIVGNLASGKSALVHRYLTGTYVQEESPEGGRFKKEIVVDGQSYLLLIRDEGGPPEAQFAMWVDAVIFVFSLEDEISFQTVYHYYSRMASYRNTSEIPLVLVGTQDAISSTNPRVIDDARARKLSSDLKRCTYYETCATYGLNVERVFQDVAQKIVATRKKQQLSIGPCKSLPNSPSHSSVCSAQVSAVHISQTSNGGGSLSDYSSSVPSTPSTSQKELRIDVPPAANTPTPVRKQSKRRSNLFTSRKGSDPDKEKKGLESRADSIGSGRAIPIKQGMLLKRSGKSLNKEWKKKYVTLCDNGVLTYHPSLHDYMQNVHGKEIDLLRTTVKVPGKRPPRATSACAPISSPKTNGLSKDMSSLHISPNSGSVASAPGSQMASGVSLGSFNSRADGMQQRSYSVSSADQWSEATVIANSAISSDTGLGDPLCSSPSISSTASPKLDPPPSPHANRKKHRRKKSTSNFKADGLSGTADEQEENFEFIIVSLTGQTWHFEATTYEERDAWVQAIESQILASLQSCESSKNKSRLTSQSEAMALQSIRNIRGNSHCVDCETQNPNWASLNLGALMCIECSGIHRNLGTHLSRVRSLDLDDWPIELIKVMSSIGNELANSVWEESTQGRTKPSLDSTREEKERWIRAKYEQKLFLAPLPCMELSLGQHLLRATADEDLRTVILLLAHGSRDEVNETCGEADGRTALHLACRKGNVVLAQLLIWYGVDVMARDAHGNTALAYARQASSQECTEVLLQYGCPDERFALMATPNLSRKNTNRNNSGGRVPTVI", "length": 1130, "header": "tr|A0AAA9TUE2-1|A0AAA9TUE2_BOVIN Isoform 1 of Arf-GAP with GTPase, ANK repeat and PH domain-containing protein 1 OS=Bos taurus OX=9913 GN=AGAP1 PE=3 SV=1 CANONICAL=A0AAA9TUE2-1" }, "locus": { "chromosome": "3", "start_pos": 115604933, "end_pos": 115201466, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000117689.1", "url": "https://www.ensembl.org/id/ENSBTAT00000117689.1" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000102231.1", "url": "https://www.ensembl.org/id/ENSBTAP00000102231.1" } ] } }, { "isoform_ac": "F1MGL2-1", "url": "https://www.uniprot.org/uniprotkb/F1MGL2/entry", "sequence": { "sequence": "MNYQQQLANSAAIRAEIQRFESVHPNIYSIYELLERVEEPVLQNQIREHVIAIEDAFVNSQEWTLSRSVPELKVGIVGNLASGKSALVHRYLTGTYVQEESPEGGRFKKEIVVDGQSYLLLIRDEGGPPEAQFAMWVDAVIFVFSLEDEISFQTVYHYYSRMASYRNTSEIPLVLVGTQDAISSTNPRVIDDARARKLSSDLKRCTYYETCATYGLNVERVFQDVAQKIVATRKKQQLSIGPCKSLPNSPSHSSVCSAQVSAVHISQTSNGGGSLSDYSSSVPSTPSTSQKELRIDVPPAANTPTPVRKQSKRRSNLFTSRKGSDPDKEKKGLESRADSIGSGRAIPIKQGMLLKRSGKSLNKEWKKKYVTLCDNGVLTYHPSLHDYMQNVHGKEIDLLRTTVKVPGKRPPRATSACAPISSPKTNGLSKDMSSLHISPNSGSVASAPGSQMASGVSLGSFNSRADGMQQRSYSVSSADQWSEATVIANSAISSDTGLGDPLCSSPSISSTASPKLDPPPSPHANRKKHRRKKSTSNFKADGLSGTADEQEENFEFIIVSLTGQTWHFEATTYEERDAWVQAIESQILASLQSCESSKNKSRLTSQSEAMALQSIRNIRGNSHCVDCETQNPNWASLNLGALMCIECSGIHRNLGTHLSRVRSLDLDDWPIELIKVMSSIGNELANSVWEESTQGRTKPSLDSTREEKERWIRAKYEQKLFLAPLPCMELSLGQHLLRATADEDLRTVILLLAHGSRDEVNETCGEADGRTALHLACRKGNVVLAQLLIWSSLLTIRDPEIESTGGHTSQQFIPMAT", "length": 817, "header": "tr|F1MGL2-1|F1MGL2_BOVIN Computationally mapped isoform of ArfGAP with GTPase domain, ankyrin repeat and PH domain 1 OS=Bos taurus OX=9913 GN=AGAP1 PE=3 SV=4 CANONICAL=A0AAA9TUE2-1" }, "locus": { "chromosome": "3", "start_pos": 115604060, "end_pos": 115044779, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000061206.4", "url": "https://www.ensembl.org/id/ENSBTAT00000061206.4" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000053769.4", "url": "https://www.ensembl.org/id/ENSBTAP00000053769.4" } ] } } ], "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "other", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 558, "start_aa": "Thr", "end_pos": 558, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr558", "evidence": [ { "id": "", "database": "GlyGen", "url": "https://data.glygen.org/" } ], "filter_code": "000000000000000010000.00000000001000.0.01000" } ], "phosphorylation": [], "glycation": [], "keywords": [ "glycoprotein", "glycoprotein_predicted" ], "publication": [], "pathway": [], "orthologs": [], "go_annotation": { "categories": [ { "name": "Molecular Function", "total": 5, "go_terms": [ { "name": "GTPase activity", "id": "GO:0003924", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003924", "evidence": [ { "database": "UniProtKB", "id": "A0AAA9TUE2", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TUE2" } ], "pmid": "" }, { "name": "GTPase activator activity", "id": "GO:0005096", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005096", "evidence": [ { "database": "UniProtKB", "id": "A0AAA9TUE2", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TUE2" } ], "pmid": "" }, { "name": "GTP binding", "id": "GO:0005525", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005525", "evidence": [ { "database": "UniProtKB", "id": "A0AAA9TUE2", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TUE2" } ], "pmid": "" }, { "name": "zinc ion binding", "id": "GO:0008270", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008270", "evidence": [ { "database": "UniProtKB", "id": "A0AAA9TUE2", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TUE2" } ], "pmid": "" }, { "name": "phospholipid binding", "id": "GO:0005543", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005543", "evidence": [ { "database": "UniProtKB", "id": "A0AAA9TUE2", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TUE2" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 1, "go_terms": [ { "name": "cytoplasm", "id": "GO:0005737", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005737", "evidence": [ { "database": "UniProtKB", "id": "A0AAA9TUE2", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TUE2" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 1, "go_terms": [ { "name": "protein transport", "id": "GO:0015031", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0015031", "evidence": [ { "database": "UniProtKB", "id": "A0AAA9TUE2", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TUE2" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 1034, "end_pos": 1036, "annotation": "n_glycosylation_sequon" }, { "start_pos": 1111, "end_pos": 1113, "annotation": "n_glycosylation_sequon" }, { "start_pos": 1120, "end_pos": 1122, "annotation": "n_glycosylation_sequon" }, { "start_pos": 240, "end_pos": 242, "annotation": "n_glycosylation_sequon" }, { "start_pos": 440, "end_pos": 442, "annotation": "n_glycosylation_sequon" }, { "start_pos": 872, "end_pos": 874, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A0AAA9TUE2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TUE2" }, { "id": "PS50115", "database": "PROSITE", "url": "https://prosite.expasy.org/PS50115" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "Arf-GAP", "eco_id": "ECO_0000259", "start_pos": 882, "end_pos": 1002, "start_aa": "Ala", "end_aa": "Glu", "glycosite_overlap": [] }, { "evidence": [ { "id": "A0AAA9TUE2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TUE2" }, { "id": "PS50003", "database": "PROSITE", "url": "https://prosite.expasy.org/PS50003" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "PH", "eco_id": "ECO_0000259", "start_pos": 619, "end_pos": 861, "start_aa": "Ile", "end_aa": "Leu", "glycosite_overlap": [] } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [ 558 ], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 1034, "end_pos": 1036 }, { "start_pos": 1111, "end_pos": 1113 }, { 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"count": 0 }, { "field": "o_linked_sites", "count": 1 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "exact_sites", "count": 1 }, { "field": "exact_o_linked_sites", "count": 1 }, { "field": "fuzzy_sites", "count": 0 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_pos", "start_aa", "end_pos", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ], "tool_support": { "graph_view": "yes" } }, { "uniprot_canonical_ac": "A0AAA9TVZ8-1", "uniprot_ac": "A0AAA9TVZ8", "uniprot_id": "A0AAA9TVZ8_BOVIN", "mass": { "chemical_mass": 108522.0, "monoisotopic_mass": 108522.0 }, "refseq": {}, "gene_names": [ { "name": "ULK2", "type": "recommended", "evidence": [ { "id": "A0AAA9TVZ8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TVZ8" } ] } ], "protein_names": [ { "name": "non-specific serine/threonine protein kinase", "type": "recommended", "evidence": [ { "id": "A0AAA9TVZ8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TVZ8/entry#names_and_taxonomy" } ] }, { "name": "2.7.11.1", "type": "synonym", "evidence": [ { "id": "A0AAA9TVZ8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TVZ8/entry#names_and_taxonomy" } ] } ], "function": [], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Bos taurus", "taxid": 9913, "evidence": [ { "database": "UniProtKB", "id": "A0AAA9TVZ8", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TVZ8" } ], "common_name": "Bovine", "glygen_name": "Bovine", "reference_species": "Bos taurus [9913]" } ], "gene": [ { "name": "ULK2", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TVZ8", "locus": { "chromosome": "19", "start_pos": 33860333, "end_pos": 33802827, "strand": "-", "evidence": [ { "database": "Ensembl Gene", "id": "ENSBTAG00000030977", "url": "https://www.ensembl.org/id/ENSBTAG00000030977" } ] } } ], "crossref": [ { "id": "A0AAA9TVZ8", "url": "https://alphafold.ebi.ac.uk/entry/A0AAA9TVZ8", "database": "AlphaFoldDB", "categories": [] }, { "id": "cd14201", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd14201", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "618601", "url": "https://www.ncbi.nlm.nih.gov/gene/618601", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR000719", "url": "https://www.ebi.ac.uk/interpro/entry/IPR000719", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR008271", "url": "https://www.ebi.ac.uk/interpro/entry/IPR008271", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR011009", "url": "https://www.ebi.ac.uk/interpro/entry/IPR011009", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR017441", "url": "https://www.ebi.ac.uk/interpro/entry/IPR017441", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR022708", "url": "https://www.ebi.ac.uk/interpro/entry/IPR022708", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR045269", "url": "https://www.ebi.ac.uk/interpro/entry/IPR045269", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR048941", "url": "https://www.ebi.ac.uk/interpro/entry/IPR048941", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "PTHR24348", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR24348", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR24348:SF18", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR24348:SF18", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00069", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00069", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF12063", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF12063", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF21127", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF21127", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "A0AAA9S629", "url": "https://www.uniprot.org/uniprotkb/A0AAA9S629", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0AAA9S629-1", "url": "https://www.uniprot.org/uniprotkb/A0AAA9S629-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0AAA9SG40", "url": "https://www.uniprot.org/uniprotkb/A0AAA9SG40", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0AAA9SG40-1", "url": "https://www.uniprot.org/uniprotkb/A0AAA9SG40-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0AAA9TM03", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TM03", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0AAA9TM03-1", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TM03-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0AAA9TVZ8", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TVZ8", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0AAA9TVZ8-1", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TVZ8-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0AAF6DLK4", "url": "https://www.uniprot.org/uniprotkb/A0AAF6DLK4", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0AAF6DLK4-1", "url": "https://www.uniprot.org/uniprotkb/A0AAF6DLK4-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MEVVGDFEYSKRDLVGHGAFAVVFRGRHRQELQHENIVALYDVQELPNSVFLVMEYCNGGDLADYLQAKGTLSEDTIRVFLHQIAAAMRILHSKGIIHRDLKPQNILLSYASRKKSSVSGIRIKIADFGFARYLHSNMMAATLCGSPMYMAPEVIMSQHYDAKADLWSIGTVIYQCLVGKPPFQANSPQDLRMFYEKNRNLMPSIPRETSPYLANLLLGLLQRNQKDRMDFEAFFSHPFLEQVPAKKSCPVPVPMYAGSASGGSYGSSPSCRFVSPPSLPDMQHIQEENLSSPPLGPPNYLQVSKDSASTSSKNSSCDTDDFVLVPHNISSDHSYDMPMGTAGRRASNEFLVFGGQCQPSVSPHSTAAPIPVPTQVRNYQRIEQNLTSTAGSSTNLHGSPRSAVVRRSNTSPLGFLRPGSCSPAPADAVPAIGRRLSTGSSRPYSPSPLVGTIPEQFRQCCCGHLQGHESRSRNSSGSPVPQAQSPQPVLLGARLQSAPTLTDIYQNKQKLRKQHSDPVCPSQAGAGYSCSPQPSRPGSLGTSPTKHTGSSPRSSDWFFRTPLPTIIGSPTKTTAPFKIPKTQASSNLLALATRHGPSEGQLKDGNNPRKCTHCVLVQGGERQKSEHQVKAAFGRSVSTGKLSDQQVKTPFGGHQGSTDSLNTERPMDTAPAGACGVALAPAIGAAASSRAVMFTVGSPPHRAAATTCTHTGLRIRTTSGGSSGSGGSLCSIGGRVCGGSPPGLCSGSPPPGAEAAPSLRHVPCGASPPSLEGLVTFEAPELPEETLMEQEHADTLRHLNSMLLFTECVLDLTAVRGGSPELCASAVSVYQIQESAVVDQISQLSKDWGRVEQLVLYMKAAQLLAASLHLAKEQIKSGKLSPSSGVKQVVKNLNERYKFCISMCKKLTEKLNRFFSDKQRFIDEINSVTAEKLIYNCAVEMVQAAALDEMFQQTEDIVYRYHKAALLLEGLTKILQDPADIENIHRYKSSIERRLSALCYSTSAL", "length": 1005, "header": "tr|A0AAA9TVZ8-1|A0AAA9TVZ8_BOVIN Isoform 1 of non-specific serine/threonine protein kinase OS=Bos taurus OX=9913 GN=ULK2 PE=4 SV=1 CANONICAL=A0AAA9TVZ8-1" }, "isoforms": [ { "isoform_ac": "A0AAA9S629-1", "url": "https://www.uniprot.org/uniprotkb/A0AAA9S629/entry", "sequence": { "sequence": "MEVVGDFEYSKRDLVGHGAFAVVFRGRHRQKTDWEVAIKSINKKNLSKSQILLGKEIKILKELQHENIVALYDVQELPNSVFLVMEYCNGGDLADYLQAKGTLSEDTIRVFLHQIAAAMRILHSKGIIHRDLKPQNILLSYASRKKSSVSGIRIKIADFGFARYLHSNMMAATLCGSPMYMAPEVIMSQHYDAKADLWSIGTVIYQCLVGKPPFQANSPQDLRMFYEKNRNLMPSIPRETSPYLANLLLGLLQRNQKDRMDFEAFFSHPFLEQVPAKKSCPVPVPMYAGSASGGSYGSSPSCRFVSPPSLPDMQHIQEENLSSPPLGPPNYLQVSKDSASTSSKNSSCDTDDFVLVPHNISSDHSYDMPMGTAGRRASNEFLVFGGQCQPSVSPHSTAAPIPVPTQVRNYQRIEQNLTSTAGSSTNLHGSPRSAVVRRSNTSPLGFLRPGSCSPAPADAVPAIGRRLSTGSSRPYSPSPLVGTIPEQFRQCCCGHLQGHESRSRNSSGSPVPQAQSPQPVLLGARLQSAPTLTDIYQNKQKLRKQHSDPVCPSQAGAGYSCSPQPSRPGSLGTSPTKHTGSSPRSSDWFFRTPLPTIIGSPTKTTAPFKIPKTQASSNLLALATRHGPSEGQLKDGNNPRKCTHCVLVQGGERQKSEHQVKAAFGRSVSTGKLSDQQVKTPFGGHQGSTDSLNTERPMDTAPAGACGVALAPAIGAAASSRAVMFTVGSPPHRAAATTCTHTGLRIRTTSGGSSGSGGSLCSIGGRVCGGSPPGLCSGSPPPGAEAAPSLRHVPCGASPPSLEGLVTFEAPELPEETLMEQEHADTLRHLNSMLLFTECVLDLTAVRGGSPELCASAVSVYQIQESAVVDQISQLSKDWGLTLCLLSLGQAGRAAGVVHESCTTPGSLSASRQRADQVREAEPVLRCEASCQKSE", "length": 935, "header": "tr|A0AAA9S629-1|A0AAA9TVZ8_BOVIN Computationally mapped isoform of non-specific serine/threonine protein kinase OS=Bos taurus OX=9913 GN=ULK2 PE=4 SV=1 CANONICAL=A0AAA9TVZ8-1" }, "locus": { "chromosome": "19", "start_pos": 33856217, "end_pos": 33803026, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000116619.2", "url": "https://www.ensembl.org/id/ENSBTAT00000116619.2" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000081395.1", "url": "https://www.ensembl.org/id/ENSBTAP00000081395.1" } ] } }, { "isoform_ac": "A0AAA9SG40-1", "url": "https://www.uniprot.org/uniprotkb/A0AAA9SG40/entry", "sequence": { "sequence": "MEVVGDFEYSKRDLVGHGAFAVVFRGRHRQKTDWEVAIKSINKKNLSKSQILLGKEIKILKELQHENIVALYDVQELPNSVFLVMEYCNGGDLADYLQAKGTLSEDTIRVFLHQIAAAMRILHSKGIIHRDLKPQNILLSYASRKKSSVSGIRIKIADFGFARYLHSNMMAATLCGSPMYMAPEVIMSQHYDAKADLWSIGTVIYQCLVGKPPFQANSPQDLRMFYEKNRNLMPSIPRETSPYLANLLLGLLQRNQKDRMDFEAFFSHPFLEQVPAKKSCPVPVPMYAGSASGGSYGSSPSCRFVSPPSLPDMQHIQEENLSSPPLGPPNYLQVSKDSASTSSKNSSCDTDDFVLVPHNISSDHSYDMPMGTAGRRASNEFLVFGGSAVVRRSNTSPLGFLRPGSCSPAPADAVPAIGRRLSTGSSRPYSPSPLVGTIPEQFRQCCCGHLQGHESRSRNSSGSPVPQAQSPQPVLLGARLQSAPTLTDIYQNKQKLRKQHSDPVCPSQAGAGYSCSPQPSRPGSLGTSPTKHTGSSPRSSDWFFRTPLPTIIGSPTKTTAPFKIPKTQASSNLLALATRHGPSEGQLKDGNNPRKCTHCVLVQGGERQKSEHQVKAAFGRSVSTGKLSDQQVKTPFGGHQGSTDSLNTERPMDTAPAGACGVALAPAIGAAASSRAVMFTVGSPPHRAAATTCTHTGLRIRTTSGGSSGSGGSLCSIGGRVCGGSPPGLCSGSPPPGAEAAPSLRHVPCGASPPSLEGLVTFEAPELPEETLMEQEHADTLRHLNSMLLFTECVLDLTAVRGGSPELCASAVSVYQIQESAVVDQISQLSKDWGRVEQLVLYMKAAQLLAASLHLAKEQIKSGKLSPSSGVKQVVKNLNERYKFCISMCKKLTEKLNRFFSDKQRFIDEINSVTAEKLIYNCAVEMVQAAALDEMFQQTEDIVYRYHKAALLLEGLTKILQDPADIENIHRYKSSIERRLSALCYSTSAL", "length": 990, "header": "tr|A0AAA9SG40-1|A0AAA9TVZ8_BOVIN Computationally mapped isoform of non-specific serine/threonine protein kinase OS=Bos taurus OX=9913 GN=ULK2 PE=4 SV=1 CANONICAL=A0AAA9TVZ8-1" }, "locus": { "chromosome": "19", "start_pos": 33858937, "end_pos": 33803026, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000104007.2", "url": "https://www.ensembl.org/id/ENSBTAT00000104007.2" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000081440.1", "url": "https://www.ensembl.org/id/ENSBTAP00000081440.1" } ] } }, { "isoform_ac": "A0AAA9TM03-1", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TM03/entry", "sequence": { "sequence": "MEVVGDFEYSKRDLVGHGAFAVVFRGRHRQKTDWEVAIKSINKKNLSKSQILLGKEIKILKELQHENIVALYDVQELPNSVFLVMEYCNGGDLADYLQAKGTLSEDTIRVFLHQIAAAMRILHSKGIIHRDLKPQNILLSYASRKKSSVSGIRIKIADFGFARYLHSNMMAATLCGSPMYMAPEVIMSQHYDAKADLWSIGTVIYQCLVGKPPFQANSPQDLRMFYEKNRNLMPSIPRETSPYLANLLLGLLQRNQKDRMDFEAFFSHPFLEQVPAKKYDMPMGTAGRRASNEFLVFGGQCQPSVSPHSTAAPIPVPTQVRNYQRIEQNLTSTAGSSTNLHGSPRSAVVRRSNTSPLGFLRPGSCSPAPADAVPAIGRRLSTGSSRPYSPSPLVGTIPEQFRQCCCGHLQGHESRSRNSSGSPVPQAQSPQPVLLGARLQSAPTLTDIYQNKQKLRKQHSDPVCPSQAGAGYSCSPQPSRPGSLGTSPTKHTGSSPRSSDWFFRTPLPTIIGSPTKTTAPFKIPKTQASSNLLALATRHGPSEGQLKDGNNPRKCTHCVLVQGGERQKSEHQVKAAFGRSVSTGKLSDQQVKTPFGGHQGSTDSLNTERPMDTAPAGACGVALAPAIGAAASSRAVMFTVGSPPHRAAATTCTHTGLRIRTTSGGSSGSGGSLCSIGGRVCGGSPPGLCSGSPPPGAEAAPSLRHVPCGASPPSLEGLVTFEAPELPEETLMEQEHADTLRHLNSMLLFTECVLDLTAVRGGSPELCASAVSVYQIQESAVVDQISQLSKDWGRVEQLVLYMKAAQLLAASLHLAKEQIKSGKLSPSSGVKQVVKNLNERYKFCISMCKKLTEKLNRFFSDKQRFIDEINSVTAEKLIYNCAVEMVQAAALDEMFQQTEDIVYRYHKAALLLEGLTKILQDPADIENIHRYKSSIERRLSALCYSTSAL", "length": 949, "header": "tr|A0AAA9TM03-1|A0AAA9TVZ8_BOVIN Computationally mapped isoform of non-specific serine/threonine protein kinase OS=Bos taurus OX=9913 GN=ULK2 PE=4 SV=1 CANONICAL=A0AAA9TVZ8-1" }, "locus": { "chromosome": "19", "start_pos": 33858937, "end_pos": 33803026, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000136041.2", "url": "https://www.ensembl.org/id/ENSBTAT00000136041.2" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000097331.1", "url": "https://www.ensembl.org/id/ENSBTAP00000097331.1" } ] } }, { "isoform_ac": "A0AAA9TVZ8-1", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TVZ8/entry", "sequence": { "sequence": "MEVVGDFEYSKRDLVGHGAFAVVFRGRHRQELQHENIVALYDVQELPNSVFLVMEYCNGGDLADYLQAKGTLSEDTIRVFLHQIAAAMRILHSKGIIHRDLKPQNILLSYASRKKSSVSGIRIKIADFGFARYLHSNMMAATLCGSPMYMAPEVIMSQHYDAKADLWSIGTVIYQCLVGKPPFQANSPQDLRMFYEKNRNLMPSIPRETSPYLANLLLGLLQRNQKDRMDFEAFFSHPFLEQVPAKKSCPVPVPMYAGSASGGSYGSSPSCRFVSPPSLPDMQHIQEENLSSPPLGPPNYLQVSKDSASTSSKNSSCDTDDFVLVPHNISSDHSYDMPMGTAGRRASNEFLVFGGQCQPSVSPHSTAAPIPVPTQVRNYQRIEQNLTSTAGSSTNLHGSPRSAVVRRSNTSPLGFLRPGSCSPAPADAVPAIGRRLSTGSSRPYSPSPLVGTIPEQFRQCCCGHLQGHESRSRNSSGSPVPQAQSPQPVLLGARLQSAPTLTDIYQNKQKLRKQHSDPVCPSQAGAGYSCSPQPSRPGSLGTSPTKHTGSSPRSSDWFFRTPLPTIIGSPTKTTAPFKIPKTQASSNLLALATRHGPSEGQLKDGNNPRKCTHCVLVQGGERQKSEHQVKAAFGRSVSTGKLSDQQVKTPFGGHQGSTDSLNTERPMDTAPAGACGVALAPAIGAAASSRAVMFTVGSPPHRAAATTCTHTGLRIRTTSGGSSGSGGSLCSIGGRVCGGSPPGLCSGSPPPGAEAAPSLRHVPCGASPPSLEGLVTFEAPELPEETLMEQEHADTLRHLNSMLLFTECVLDLTAVRGGSPELCASAVSVYQIQESAVVDQISQLSKDWGRVEQLVLYMKAAQLLAASLHLAKEQIKSGKLSPSSGVKQVVKNLNERYKFCISMCKKLTEKLNRFFSDKQRFIDEINSVTAEKLIYNCAVEMVQAAALDEMFQQTEDIVYRYHKAALLLEGLTKILQDPADIENIHRYKSSIERRLSALCYSTSAL", "length": 1005, "header": "tr|A0AAA9TVZ8-1|A0AAA9TVZ8_BOVIN Isoform 1 of non-specific serine/threonine protein kinase OS=Bos taurus OX=9913 GN=ULK2 PE=4 SV=1 CANONICAL=A0AAA9TVZ8-1" }, "locus": { "chromosome": "19", "start_pos": 33858937, "end_pos": 33803026, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000133681.2", "url": "https://www.ensembl.org/id/ENSBTAT00000133681.2" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000100785.1", "url": "https://www.ensembl.org/id/ENSBTAP00000100785.1" } ] } }, { "isoform_ac": "A0AAF6DLK4-1", "url": "https://www.uniprot.org/uniprotkb/A0AAF6DLK4/entry", "sequence": { "sequence": "MPMGTAGRRASNEFLVFGGQCQPSVSPHSTAAPIPVPTQVRNYQRIEQNLTSTAGSSTNLHGSPRSAVVRRSNTSPLGFLRPGSCSPAPADAVPAIGRRLSTGSSRPYSPSPLVGTIPEQFRQCCCGHLQGHESRSRNSSGSPVPQAQSPQPVLLGARLQSAPTLTDIYQNKQKLRKQHSDPVCPSQAGAGYSCSPQPSRPGSLGTSPTKHTGSSPRSSDWFFRTPLPTIIGSPTKTTAPFKIPKTQASSNLLALATRHGPSEGQLKDGNNPRKCTHCVLVQGGERQKSEHQVKAAFGRSVSTGKLSDQQVKTPFGGHQGSTDSLNTERPMDTAPAGACGVALAPAIGAAASSRAVMFTVGSPPHRAAATTCTHTGLRIRTTSGGSSGSGGSLCSIGGRVCGGSPPGLCSGSPPPGAEAAPSLRHVPCGASPPSLEGLVTFEAPELPEETLMEVGRDPTIQVGFALARTCRHLTPPELNAAVHGVCAGPDGCARGEPGALRIRRLRVPDPGECGGGPDQPAEQGLGAGRAAGVVHESCTTPGSLSASRQRADQVREAEPVLRCEASCQKSE", "length": 571, "header": "tr|A0AAF6DLK4-1|A0AAF6DLK4_BOVIN Computationally mapped isoform of Unc-51 like autophagy activating kinase 2 OS=Bos taurus OX=9913 GN=ULK2 PE=4 SV=1 CANONICAL=A0AAA9TVZ8-1" }, "locus": { "chromosome": "19", "start_pos": 33856217, "end_pos": 33839772, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000004466.7", "url": "https://www.ensembl.org/id/ENSBTAT00000004466.7" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000004466.6", "url": "https://www.ensembl.org/id/ENSBTAP00000004466.6" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [ "enzyme" ], "publication": [], "pathway": [], "orthologs": [], "go_annotation": { "categories": [ { "name": "Molecular Function", "total": 2, "go_terms": [ { "name": "protein serine/threonine kinase activity", "id": "GO:0004674", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0004674", "evidence": [ { "database": "UniProtKB", "id": "A0AAA9TVZ8", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TVZ8" } ], "pmid": "" }, { "name": "ATP binding", "id": "GO:0005524", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005524", "evidence": [ { "database": "UniProtKB", "id": "A0AAA9TVZ8", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TVZ8" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 3, "go_terms": [ { "name": "regulation of autophagy", "id": "GO:0010506", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0010506", "evidence": [ { "database": "UniProtKB", "id": "A0AAA9TVZ8", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TVZ8" } ], "pmid": "" }, { "name": "autophagy", "id": "GO:0006914", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006914", "evidence": [ { "database": "UniProtKB", "id": "A0AAA9TVZ8", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TVZ8" } ], "pmid": "" }, { "name": "response to starvation", "id": "GO:0042594", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0042594", "evidence": [ { "database": "UniProtKB", "id": "A0AAA9TVZ8", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TVZ8" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 1, "go_terms": [ { "name": "phagophore assembly site membrane", "id": "GO:0034045", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0034045", "evidence": [ { "database": "UniProtKB", "id": "A0AAA9TVZ8", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TVZ8" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 289, "end_pos": 291, "annotation": "n_glycosylation_sequon" }, { "start_pos": 314, "end_pos": 316, "annotation": "n_glycosylation_sequon" }, { "start_pos": 328, "end_pos": 330, "annotation": "n_glycosylation_sequon" }, { "start_pos": 385, "end_pos": 387, "annotation": "n_glycosylation_sequon" }, { "start_pos": 409, "end_pos": 411, "annotation": "n_glycosylation_sequon" }, { "start_pos": 474, "end_pos": 476, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A0AAA9TVZ8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TVZ8" }, { "id": "PS50011", "database": "PROSITE", "url": "https://prosite.expasy.org/PS50011" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "Protein kinase", "eco_id": "ECO_0000259", "start_pos": 1, "end_pos": 240, "start_aa": "Met", "end_aa": "Leu", "glycosite_overlap": [] } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [ { "ec_number": "2.7.11.1", "ec_name": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "2.7.11.1", "database": "Rhea", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.1" }, { "id": "2.7.11.1", "database": "BRENDA Enzymes", "url": "https://www.brenda-enzymes.org/enzyme.php?ecno=2.7.11.1" } ] } ], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 289, "end_pos": 291 }, { "start_pos": 314, "end_pos": 316 }, { "start_pos": 328, "end_pos": 330 }, { "start_pos": 385, "end_pos": 387 }, { "start_pos": 409, "end_pos": 411 }, { "start_pos": 474, "end_pos": 476 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", 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"table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ], "tool_support": { "graph_view": "yes" } }, { "uniprot_canonical_ac": "A0AAA9TWA0-1", "uniprot_ac": "A0AAA9TWA0", "uniprot_id": "A0AAA9TWA0_BOVIN", "mass": { "chemical_mass": 234340.0, "monoisotopic_mass": 234340.0 }, "refseq": { "ac": "XP_059744067", "name": "phospholipid-transporting ATPase ABCA7 isoform X1", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_059744067" }, "gene_names": [ { "name": "ABCA7", "type": "recommended", "evidence": [ { "id": "A0AAA9TWA0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TWA0" } ] }, { "name": "ABCA7", "type": "synonym", "evidence": [ { "id": "XP_059744067", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_059744067" } ] } ], "protein_names": [ { "name": "ATP binding cassette subfamily A member 7", "type": "synonym", "evidence": [ { "id": "A0AAA9TWA0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TWA0/entry#names_and_taxonomy" } ] }, { "name": "phospholipid-transporting ATPase ABCA7 isoform X1", "type": "synonym", "evidence": [ { "id": "XP_059744067", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_059744067" } ] } ], "function": [], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Bos taurus", "taxid": 9913, "evidence": [ { "database": "UniProtKB", "id": "A0AAA9TWA0", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TWA0" } ], "common_name": "Bovine", "glygen_name": "Bovine", "reference_species": "Bos taurus [9913]" } ], "gene": [ { "name": "ABCA7", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TWA0", "locus": { "chromosome": "7", "start_pos": 43561826, "end_pos": 43545179, "strand": "-", "evidence": [ { "database": "Ensembl Gene", "id": "ENSBTAG00000020766", "url": "https://www.ensembl.org/id/ENSBTAG00000020766" } ] } } ], "crossref": [ { "id": "cd03263", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd03263", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "511762", "url": "https://www.ncbi.nlm.nih.gov/gene/511762", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR003439", "url": "https://www.ebi.ac.uk/interpro/entry/IPR003439", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR003593", "url": "https://www.ebi.ac.uk/interpro/entry/IPR003593", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR013525", "url": "https://www.ebi.ac.uk/interpro/entry/IPR013525", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR017871", "url": "https://www.ebi.ac.uk/interpro/entry/IPR017871", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR026082", "url": "https://www.ebi.ac.uk/interpro/entry/IPR026082", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR027417", "url": "https://www.ebi.ac.uk/interpro/entry/IPR027417", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR056264", "url": "https://www.ebi.ac.uk/interpro/entry/IPR056264", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "PTHR19229", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR19229", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR19229:SF49", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR19229:SF49", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00005", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00005", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF12698", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF12698", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF23321", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF23321", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "XP_059744067", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_059744067", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0AAA9S7U2", "url": "https://www.uniprot.org/uniprotkb/A0AAA9S7U2", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0AAA9S7U2-1", "url": "https://www.uniprot.org/uniprotkb/A0AAA9S7U2-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0AAA9TER4", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TER4", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0AAA9TER4-1", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TER4-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0AAA9TWA0", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TWA0", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0AAA9TWA0-1", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TWA0-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MAFWTQLMLLLWKNFLYRRRQPIQLLVELLWPLFLFFILVAVRHSHPPLEQHECHFPNKPLPSAGTIPWLQGLICNVNNTCFPWQTPGEEPGVLSNFKDSLVSRLLADARTVLGGPSAHRMLASLRKLMPILKAAHTARATFPWPSEQPKEGLSLATQLLGTLLQGESLGSVLGHAQESVGSLVETAEDMAQELLELPSLGELWALLQRPHRPGGPLEAVAEALCSARGPSKPGGPSLNWYEASDLKELVGQEPAQALRDNSLSPTCAELTGGLDTHPLSRLLWRRLKPLVLGKVLFTPDTPFTRQIMAQVNRTFQELALLKDIQEVWGLLGPQLFNFLNDSANVAMLQRLLQIQDKGRRQPRPGGGARVEALRAFLNPRSGGYSWQKAHADVGHLAVTLGRVMECVTLDKLEAAPSEAALVERALKLLSEHRFWAGIVFLGPEDSPDPAQSPGPGHVRIKIRMDIDDVERTNKIKDRFWDPGPAADPLTDLRYVWGGFVYLQDLLERAAVRVLTGTTPHAGLYLQQMPYPCYVDDTFLRVLSRSLPLFLTLAWIYSVALTVKAVVREKETRLRYTMRAMGLSATALWLGWFLSCLGPFLLSTALLVLVLKLGDILPYSHPGVLFLFLAAFAVATVVQSFLLSAFFSRANLAAACGGLAYFVLYLPYVLCVAWRDQLPMGGRVAASLLSPVAFGFGCESLALLEEQGEGAQWHNLGTGPTADVFSLAQVSGLLLLDAALYGLATWYLEAVCPGEYGIPEPWNFPFRRSYWFGSQTPKGPAPVLTAQDPKVLVEEAPPGLIPGVSIRGLEKRFAGNPQPALCGLSLDFYQGHITAFLGHNGAGKTTTMSILSGLFPPTAGSASVLGHDVRTSMVAIRPCLGVCPQYNVLFDLLTVDEHIWFYGRLKGLSAAAVGPEQDRLLQDMGLIPKRHAQTHHLSGGMQRKLSVAIAFVGGSQVVILDEPTAGVDPTSRRGIWELLLKYREGRTLILSTHHLDEAELLGDRVAVVAGGRLCCCGSPLFLRRHLGSGYYLTLAKGPPPLATSKKGEAGLKNSMDAGQKREPGSQASSAGAAQLWAIVQRHVPGTRLVKDLPHELVLALPYKGALDGSFAELFHDLDQRLGELGLAGYGISDTSLEEIFLKVVEDCAVDAGPEDGRPRQGPCLGIAHPDATRKLQVPPEETALENGGLVGSAPETQALQGSGPTTAGLVHSWALTYQQLRALLLKRFLLARRSRRGLFAQIVLPALFVGLALVFSLIAPPFGYYPALQLSPSMYGSQVSFFSDDTPGDPEHARLLEALLEEAGLEEPYLKSNSSRAPACTRPALCHFSVPDVPADMAEVLASGNWTPESPSPACQCSQPGARRLLPDCPAAAGGPPPPQAPTSSGEVVQNLTGRNLSDFLVKTYPRLVRQGLKTKKWVNEVRYGGFSLEGRDPGLPSGLEVGRSLEELRALLNPAPGEALDHLLNNLTAWAVGLDTQDGLKIWFNNKGWHAMVAFVNRANNALLRAHLPPGSSHHAHSITTLNHPLNLTKEQLSEAALMASSVDVLVSICVVFAMSFVPASFILVLIDERVTRAKHLQCMGGLPPTLYWLGNFLWDMCNYLVSACIVVLIFLAFQQRAYVAPANLPALLLLLLLYGWSITPLMYPASFFFSVPSTAYVVLTCINLFIGINGSMATFVLELFSDQKLQKVSRILKQVFLIFPHFCLGRGLIDMVRNQAMADAFERLGEGYFQSPLRWEVVGKNLLAMFIQGPIFLLFTLLLQHHNRLLPQPKLRPLPALGEEDEDVARERERVVQGATQGDVLVLRDLTKVYPGQRTPAVDRLCLGIPPGECFGLLGVNGAGKTSTFRMVTGDTLPSGGEAILEGHSVAQEPAAAHRRMGYCPQSDAIFELLTGREHLELYARLRGVPEAQVAQTASYGLARLGLSQYADQPAGTYSGGNKRKLATAVALVGDPALVFLDEPTTGMDPGARRFLWNSLLAVVQEGRSVVLTSHSMEECEALCTRLAIMVNGRFCCLGSAQHLKGRFGAGHTLTLRVPLSRSKLAADFVAQAFPGAELREAHGGRLRFQLLPGGRCTLALVFGLLAAHGAEHGVEDFSVSQTTLEEVFLYFSKDQGKEEDEKETEVGADPVLGPQHPKLITQFLDDHSMAETVL", "length": 2152, "header": "tr|A0AAA9TWA0-1|A0AAA9TWA0_BOVIN Isoform 1 of ATP binding cassette subfamily A member 7 OS=Bos taurus OX=9913 GN=ABCA7 PE=3 SV=1 CANONICAL=A0AAA9TWA0-1" }, "isoforms": [ { "isoform_ac": "A0AAA9S7U2-1", "url": "https://www.uniprot.org/uniprotkb/A0AAA9S7U2/entry", "sequence": { "sequence": 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"length": 2035, "header": "tr|A0AAA9S7U2-1|A0AAA9TWA0_BOVIN Computationally mapped isoform of ATP binding cassette subfamily A member 7 OS=Bos taurus OX=9913 GN=ABCA7 PE=3 SV=1 CANONICAL=A0AAA9TWA0-1" }, "locus": { "chromosome": "7", "start_pos": 43561709, "end_pos": 43545315, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000093616.1", "url": "https://www.ensembl.org/id/ENSBTAT00000093616.1" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000080008.1", "url": "https://www.ensembl.org/id/ENSBTAP00000080008.1" } ] } }, { "isoform_ac": "A0AAA9TER4-1", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TER4/entry", "sequence": { "sequence": "MAFWTQLMLLLWKNFLYRRRQPIQLLVELLWPLFLFFILVAVRHSHPPLEQHECHFPNKPLPSAGTIPWLQGLICNVNNTCFPWQTPGEEPGVLSNFKDSLVSRLLADARTVLGGPSAHRMLASLRKLMPILKAAHTARATFPWPSEQPKEGLSLATQLLGTLLQGESLGSVLGHAQESVGSLVETAEDMAQELLELPSLGELWALLQRPHRPGGPLEAVAEALCSARGPSKPGGPSLNWYEASDLKELVGQEPAQALRDNSLSPTCAELTGGLDTHPLSRLLWRRLKPLVLGKVLFTPDTPFTRQIMAQVNRTFQELALLKDIQEVWGLLGPQLFNFLNDSANVAMLQRLLQIQDKGRRQPRPGGGARVEALRAFLNPRSGGYSWQKAHADVGHLAVTLGRVMECVTLDKLEAAPSEAALVERALKLLSEHRFWAGIVFLGPEDSPDPAQSPGPGHVRIKIRMDIDDVERTNKIKDRFWDPGPAADPLTDLRYVWGGFVYLQDLLERAAVRVLTGTTPHAGLYLQQMPYPCYVDDTFLRVLSRSLPLFLTLAWIYSVALTVKAVVREKETRLRYTMRAMGLSATALWLGWFLSCLGPFLLSTALLVLVLKSLLSPVAFGFGCESLALLEEQGEGAQWHNLGTGPTADVFSLAQVSGLLLLDAALYGLATWYLEAVCPGEYGIPEPWNFPFRRSYWFGSQTPKGPAPVLTAQDPKVLVEEAPPGLIPGVSIRGLEKRFAGNPQPALCGLSLDFYQGHITAFLGHNGAGKTTTMSILSGLFPPTAGSASVLGHDVRTSMVAIRPCLGVCPQYNVLFDLLTVDEHIWFYGRLKGLSAAAVGPEQDRLLQDMGLIPKRHAQTHHLSGGMQRKLSVAIAFVGGSQVVILDEPTAGVDPTSRRGIWELLLKYREGRTLILSTHHLDEAELLGDRVAVVAGGRLCCCGSPLFLRRHLGSGYYLTLAKGPPPLATSKKGEAGLKNSMDAGQKREPGSQASSAGAAQLWAIVQRHVPGTRLVKDLPHELVLALPYKGALDGSFAELFHDLDQRLGELGLAGYGISDTSLEEIFLKVVEDCAVDAGPEDGRPRQGPCLGIAHPDATRKLQVPPEETALENGGLVGSAPETQALQGSGPTTAGLVHSWALTYQQLRALLLKRFLLARRSRRGLFAQIVLPALFVGLALVFSLIAPPFGYYPALQLSPSMYGSQVSFFSDDTPGDPEHARLLEALLEEAGLEEPYLKSNSSRAPACTRPALCHFSVPDVPADMAEVLASGNWTPESPSPACQCSQPGARRLLPDCPAAAGGPPPPQAPTSSGEVVQNLTGRNLSDFLVKTYPRLVRQGLKTKKWVNEVRYGGFSLEGRDPGLPSGLEVGRSLEELRALLNPAPGEALDHLLNNLTAWAVGLDTQDGLKIWFNNKGWHAMVAFVNRANNALLRAHLPPGSSHHAHSITTLNHPLNLTKEQLSEAALMASSVDVLVSICVVFAMSFVPASFILVLIDERVTRAKHLQCMGGLPPTLYWLGNFLWDMCNYLVSACIVVLIFLAFQQRAYVAPANLPALLLLLLLYGWSITPLMYPASFFFSVPSTAYVVLTCINLFIGINGSMATFVLELFSDQKLQKVSRILKQVFLIFPHFCLGRGLIDMVRNQAMADAFERLGEGYFQSPLRWEVVGKNLLAMFIQGPIFLLFTLLLQHHNRLLPQPKLRPLPALGEEDEDVARERERVVQGATQGDVLVLRDLTKVGVGWGASTAGLGGPPLAHPPFSWTSSSQVYPGQRTPAVDRLCLGIPPGECFGLLGVNGAGKTSTFRMVTGDTLPSGGEAILEGHSVAQEPAAAHRRMGYCPQSDAIFELLTGREHLELYARLRGVPEAQVAQTASYGLARLGLSQYADQPAGTYSGGNKRKLATAVALVGDPALVFLDEPTTGMDPGARRFLWNSLLAVVQEGRSVVLTSHSMEECEALCTRLAIMVNGRFCCLGSAQHLKGRFGAGHTLTLRVPLSRSKLAADFVAQAFPGAELREAHGGRLRFQLLPGGRCTLALVFGLLAAHGAEHGVEDFSVSQTTLEEVFLYFSKDQGKEEDEKETEVGADPVLGPQHPKLITQFLDDHSMAETVL", "length": 2107, "header": "tr|A0AAA9TER4-1|A0AAA9TWA0_BOVIN Computationally mapped isoform of ATP binding cassette subfamily A member 7 OS=Bos taurus OX=9913 GN=ABCA7 PE=3 SV=1 CANONICAL=A0AAA9TWA0-1" }, "locus": { "chromosome": "7", "start_pos": 43561709, "end_pos": 43545315, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000119591.1", "url": "https://www.ensembl.org/id/ENSBTAT00000119591.1" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000095469.1", "url": "https://www.ensembl.org/id/ENSBTAP00000095469.1" } ] } }, { "isoform_ac": "A0AAA9TWA0-1", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TWA0/entry", "sequence": { "sequence": "MAFWTQLMLLLWKNFLYRRRQPIQLLVELLWPLFLFFILVAVRHSHPPLEQHECHFPNKPLPSAGTIPWLQGLICNVNNTCFPWQTPGEEPGVLSNFKDSLVSRLLADARTVLGGPSAHRMLASLRKLMPILKAAHTARATFPWPSEQPKEGLSLATQLLGTLLQGESLGSVLGHAQESVGSLVETAEDMAQELLELPSLGELWALLQRPHRPGGPLEAVAEALCSARGPSKPGGPSLNWYEASDLKELVGQEPAQALRDNSLSPTCAELTGGLDTHPLSRLLWRRLKPLVLGKVLFTPDTPFTRQIMAQVNRTFQELALLKDIQEVWGLLGPQLFNFLNDSANVAMLQRLLQIQDKGRRQPRPGGGARVEALRAFLNPRSGGYSWQKAHADVGHLAVTLGRVMECVTLDKLEAAPSEAALVERALKLLSEHRFWAGIVFLGPEDSPDPAQSPGPGHVRIKIRMDIDDVERTNKIKDRFWDPGPAADPLTDLRYVWGGFVYLQDLLERAAVRVLTGTTPHAGLYLQQMPYPCYVDDTFLRVLSRSLPLFLTLAWIYSVALTVKAVVREKETRLRYTMRAMGLSATALWLGWFLSCLGPFLLSTALLVLVLKLGDILPYSHPGVLFLFLAAFAVATVVQSFLLSAFFSRANLAAACGGLAYFVLYLPYVLCVAWRDQLPMGGRVAASLLSPVAFGFGCESLALLEEQGEGAQWHNLGTGPTADVFSLAQVSGLLLLDAALYGLATWYLEAVCPGEYGIPEPWNFPFRRSYWFGSQTPKGPAPVLTAQDPKVLVEEAPPGLIPGVSIRGLEKRFAGNPQPALCGLSLDFYQGHITAFLGHNGAGKTTTMSILSGLFPPTAGSASVLGHDVRTSMVAIRPCLGVCPQYNVLFDLLTVDEHIWFYGRLKGLSAAAVGPEQDRLLQDMGLIPKRHAQTHHLSGGMQRKLSVAIAFVGGSQVVILDEPTAGVDPTSRRGIWELLLKYREGRTLILSTHHLDEAELLGDRVAVVAGGRLCCCGSPLFLRRHLGSGYYLTLAKGPPPLATSKKGEAGLKNSMDAGQKREPGSQASSAGAAQLWAIVQRHVPGTRLVKDLPHELVLALPYKGALDGSFAELFHDLDQRLGELGLAGYGISDTSLEEIFLKVVEDCAVDAGPEDGRPRQGPCLGIAHPDATRKLQVPPEETALENGGLVGSAPETQALQGSGPTTAGLVHSWALTYQQLRALLLKRFLLARRSRRGLFAQIVLPALFVGLALVFSLIAPPFGYYPALQLSPSMYGSQVSFFSDDTPGDPEHARLLEALLEEAGLEEPYLKSNSSRAPACTRPALCHFSVPDVPADMAEVLASGNWTPESPSPACQCSQPGARRLLPDCPAAAGGPPPPQAPTSSGEVVQNLTGRNLSDFLVKTYPRLVRQGLKTKKWVNEVRYGGFSLEGRDPGLPSGLEVGRSLEELRALLNPAPGEALDHLLNNLTAWAVGLDTQDGLKIWFNNKGWHAMVAFVNRANNALLRAHLPPGSSHHAHSITTLNHPLNLTKEQLSEAALMASSVDVLVSICVVFAMSFVPASFILVLIDERVTRAKHLQCMGGLPPTLYWLGNFLWDMCNYLVSACIVVLIFLAFQQRAYVAPANLPALLLLLLLYGWSITPLMYPASFFFSVPSTAYVVLTCINLFIGINGSMATFVLELFSDQKLQKVSRILKQVFLIFPHFCLGRGLIDMVRNQAMADAFERLGEGYFQSPLRWEVVGKNLLAMFIQGPIFLLFTLLLQHHNRLLPQPKLRPLPALGEEDEDVARERERVVQGATQGDVLVLRDLTKVYPGQRTPAVDRLCLGIPPGECFGLLGVNGAGKTSTFRMVTGDTLPSGGEAILEGHSVAQEPAAAHRRMGYCPQSDAIFELLTGREHLELYARLRGVPEAQVAQTASYGLARLGLSQYADQPAGTYSGGNKRKLATAVALVGDPALVFLDEPTTGMDPGARRFLWNSLLAVVQEGRSVVLTSHSMEECEALCTRLAIMVNGRFCCLGSAQHLKGRFGAGHTLTLRVPLSRSKLAADFVAQAFPGAELREAHGGRLRFQLLPGGRCTLALVFGLLAAHGAEHGVEDFSVSQTTLEEVFLYFSKDQGKEEDEKETEVGADPVLGPQHPKLITQFLDDHSMAETVL", "length": 2152, "header": "tr|A0AAA9TWA0-1|A0AAA9TWA0_BOVIN Isoform 1 of ATP binding cassette subfamily A member 7 OS=Bos taurus OX=9913 GN=ABCA7 PE=3 SV=1 CANONICAL=A0AAA9TWA0-1" }, "locus": { "chromosome": "7", "start_pos": 43561709, "end_pos": 43545315, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000020083.6", "url": "https://www.ensembl.org/id/ENSBTAT00000020083.6" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000102606.1", "url": "https://www.ensembl.org/id/ENSBTAP00000102606.1" } ] } } ], "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "other", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 1204, "start_aa": "Thr", "end_pos": 1204, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr1204", "evidence": [ { "id": "", "database": "GlyGen", "url": "https://data.glygen.org/" } ], "filter_code": "000000000000000010000.00000000001000.0.01000" }, { "glytoucan_ac": "", "type": "O-linked", "subtype": "other", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 720, "start_aa": "Thr", "end_pos": 720, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr720", "evidence": [ { "id": "", "database": "GlyGen", "url": "https://data.glygen.org/" } ], "filter_code": "000000000000000010000.00000000001000.0.01000" } ], "phosphorylation": [], "glycation": [], "keywords": [ "glycoprotein", "glycoprotein_predicted" ], "publication": [], "pathway": [], "orthologs": [], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 5, "go_terms": [ { "name": "Golgi membrane", "id": "GO:0000139", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000139", "evidence": [ { "database": "UniProtKB", "id": "A0AAA9TWA0", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TWA0" } ], "pmid": "" }, { "name": "phagocytic cup", "id": "GO:0001891", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0001891", "evidence": [ { "database": "UniProtKB", "id": "A0AAA9TWA0", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TWA0" } ], "pmid": "" }, { "name": "early endosome membrane", "id": "GO:0031901", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0031901", "evidence": [ { "database": "UniProtKB", "id": "A0AAA9TWA0", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TWA0" } ], "pmid": "" }, { "name": "ruffle membrane", "id": "GO:0032587", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0032587", "evidence": [ { "database": "UniProtKB", "id": "A0AAA9TWA0", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TWA0" } ], "pmid": "" }, { "name": "cell junction", "id": "GO:0030054", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030054", "evidence": [ { "database": "UniProtKB", "id": "A0AAA9TWA0", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TWA0" } ], "pmid": "" } ] }, { "name": "Molecular Function", "total": 7, "go_terms": [ { "name": "ATP binding", "id": "GO:0005524", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005524", "evidence": [ { "database": "UniProtKB", "id": "A0AAA9TWA0", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TWA0" } ], "pmid": "" }, { "name": "ATP hydrolysis activity", "id": "GO:0016887", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016887", "evidence": [ { "database": "UniProtKB", "id": "A0AAA9TWA0", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TWA0" } ], "pmid": "" }, { "name": "phospholipid transporter activity", "id": "GO:0005548", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005548", "evidence": [ { "database": "UniProtKB", "id": "A0AAA9TWA0", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TWA0" } ], "pmid": "" }, { "name": "apolipoprotein A-I receptor activity", "id": "GO:0034188", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0034188", "evidence": [ { "database": "UniProtKB", "id": "A0AAA9TWA0", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TWA0" } ], "pmid": "" }, { "name": "ABC-type transporter activity", "id": "GO:0140359", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0140359", "evidence": [ { "database": "UniProtKB", "id": "A0AAA9TWA0", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TWA0" } ], "pmid": "" }, { "name": "phosphatidylcholine floppase activity", "id": "GO:0090554", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0090554", "evidence": [ { "database": "UniProtKB", "id": "A0AAA9TWA0", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TWA0" } ], "pmid": "" }, { "name": "phosphatidylserine floppase activity", "id": "GO:0090556", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0090556", "evidence": [ { "database": "UniProtKB", "id": "A0AAA9TWA0", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TWA0" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 8, "go_terms": [ { "name": "phospholipid efflux", "id": "GO:0033700", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0033700", "evidence": [ { "database": "UniProtKB", "id": "A0AAA9TWA0", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TWA0" } ], "pmid": "" }, { "name": "phagocytosis", "id": "GO:0006909", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006909", "evidence": [ { "database": "UniProtKB", "id": "A0AAA9TWA0", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TWA0" } ], "pmid": "" }, { "name": "membrane organization", "id": "GO:0061024", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0061024", "evidence": [ { "database": "UniProtKB", "id": "A0AAA9TWA0", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TWA0" } ], "pmid": "" }, { "name": "regulation of amyloid precursor protein catabolic process", "id": "GO:1902991", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:1902991", "evidence": [ { "database": "UniProtKB", "id": "A0AAA9TWA0", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TWA0" } ], "pmid": "" }, { "name": "cholesterol efflux", "id": "GO:0033344", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0033344", "evidence": [ { "database": "UniProtKB", "id": "A0AAA9TWA0", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TWA0" } ], "pmid": "" }, { "name": "amyloid-beta formation", "id": "GO:0034205", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0034205", "evidence": [ { "database": "UniProtKB", "id": "A0AAA9TWA0", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TWA0" } ], "pmid": "" }, { "name": "phospholipid translocation", "id": "GO:0045332", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0045332", "evidence": [ { "database": "UniProtKB", "id": "A0AAA9TWA0", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TWA0" } ], "pmid": "" }, { "name": "high-density lipoprotein particle assembly", "id": "GO:0034380", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0034380", "evidence": [ { "database": "UniProtKB", "id": "A0AAA9TWA0", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TWA0" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 1312, "end_pos": 1314, "annotation": "n_glycosylation_sequon" }, { "start_pos": 1344, "end_pos": 1346, "annotation": "n_glycosylation_sequon" }, { "start_pos": 1390, "end_pos": 1392, "annotation": "n_glycosylation_sequon" }, { "start_pos": 1395, "end_pos": 1397, "annotation": "n_glycosylation_sequon" }, { "start_pos": 1466, "end_pos": 1468, "annotation": "n_glycosylation_sequon" }, { "start_pos": 1527, "end_pos": 1529, "annotation": "n_glycosylation_sequon" }, { "start_pos": 1670, "end_pos": 1672, "annotation": "n_glycosylation_sequon" }, { "start_pos": 312, "end_pos": 314, "annotation": "n_glycosylation_sequon" }, { "start_pos": 340, "end_pos": 342, "annotation": "n_glycosylation_sequon" }, { "start_pos": 78, "end_pos": 80, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A0AAA9TWA0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TWA0" }, { "id": "PS50893", "database": "PROSITE", "url": "https://prosite.expasy.org/PS50893" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "ABC transporter", "eco_id": "ECO_0000259", "start_pos": 803, "end_pos": 1034, "start_aa": "Val", "end_aa": "Ala", "glycosite_overlap": [] } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [ 720, 1204 ], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 1312, "end_pos": 1314 }, { "start_pos": 1344, "end_pos": 1346 }, { "start_pos": 1390, "end_pos": 1392 }, { "start_pos": 1395, "end_pos": 1397 }, { "start_pos": 1466, "end_pos": 1468 }, { "start_pos": 1527, "end_pos": 1529 }, { "start_pos": 1670, "end_pos": 1672 }, { "start_pos": 312, "end_pos": 314 }, { "start_pos": 340, "end_pos": 342 }, { "start_pos": 78, "end_pos": 80 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 2 }, { "field": "total_sites", "count": 2 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 2 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "exact_sites", "count": 2 }, { "field": "exact_o_linked_sites", "count": 2 }, { "field": "fuzzy_sites", "count": 0 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", 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"uniprot_canonical_ac": "A0AAA9TVV0-1", "uniprot_ac": "A0AAA9TVV0", "uniprot_id": "A0AAA9TVV0_BOVIN", "mass": { "chemical_mass": 105033.0, "monoisotopic_mass": 105033.0 }, "refseq": {}, "gene_names": [ { "name": "INCENP", "type": "recommended", "evidence": [ { "id": "A0AAA9TVV0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TVV0" } ] } ], "protein_names": [ { "name": "Inner centromere protein", "type": "recommended", "evidence": [ { "id": "A0AAA9TVV0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TVV0/entry#names_and_taxonomy" } ] } ], "function": [], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Bos taurus", "taxid": 9913, "evidence": [ { "database": "UniProtKB", "id": "A0AAA9TVV0", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TVV0" } ], "common_name": "Bovine", "glygen_name": "Bovine", "reference_species": "Bos taurus [9913]" } ], "gene": [ { "name": "INCENP", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TVV0", "locus": { "chromosome": "29", "start_pos": 40632282, "end_pos": 40596205, "strand": "-", "evidence": [ { "database": "Ensembl Gene", "id": "ENSBTAG00000050061", "url": "https://www.ensembl.org/id/ENSBTAG00000050061" } ] } } ], "crossref": [ { "id": "A0AAA9TVV0", "url": "https://alphafold.ebi.ac.uk/entry/A0AAA9TVV0", "database": "AlphaFoldDB", "categories": [] }, { "id": "ENSBTAG00000050061", "url": "https://bgee.org/?page=gene&gene_id=ENSBTAG00000050061", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "IPR005635", "url": "https://www.ebi.ac.uk/interpro/entry/IPR005635", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR022006", "url": "https://www.ebi.ac.uk/interpro/entry/IPR022006", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "A0A3Q1MAP0", "url": "https://www.orthodb.org/?gene=A0A3Q1MAP0", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR13142", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR13142", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR13142:SF1", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR13142:SF1", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF03941", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF03941", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF12178", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF12178", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "R-BTA-141430", "url": "https://www.reactome.org/PathwayBrowser/#R-BTA-141430", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "R-BTA-141444", "url": "https://www.reactome.org/PathwayBrowser/#R-BTA-141444", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "R-BTA-2467813", "url": "https://www.reactome.org/PathwayBrowser/#R-BTA-2467813", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "R-BTA-2500257", "url": "https://www.reactome.org/PathwayBrowser/#R-BTA-2500257", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "R-BTA-4615885", "url": "https://www.reactome.org/PathwayBrowser/#R-BTA-4615885", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "R-BTA-5663220", "url": "https://www.reactome.org/PathwayBrowser/#R-BTA-5663220", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "R-BTA-9648025", "url": "https://www.reactome.org/PathwayBrowser/#R-BTA-9648025", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "A0A3Q1MAP0", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1MAP0", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A3Q1MAP0-1", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1MAP0-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0AAA9S8B8", "url": "https://www.uniprot.org/uniprotkb/A0AAA9S8B8", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0AAA9S8B8-1", "url": "https://www.uniprot.org/uniprotkb/A0AAA9S8B8-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0AAA9TVV0", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TVV0", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0AAA9TVV0-1", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TVV0-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0AAA9TW12", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TW12", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0AAA9TW12-1", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TW12-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MGTTAQGPIHLLELCDQKLLEFVCNVDNKDMLWLEEIEEEAQRMFTREFSKEPELMPRTPSQKNRRKKRRISSTQDENRDPVRKRLSRRKTRSSQRISRHLRSKDKVEKLATVVGENGSVLQRVTRAAAAAAAASVATAPPSPTCRSPTVLTKNPKESPTQCQLVPAVEIGASERRSAEQHLNHLQSAQAPTSTLAPASHIPSSSDEDSTPQKAEAGRLESVTVSSLMTTPRDPKGRGAGAGRSASKLRIAAAAPGPQDSPSSPASPWRERVLAPLQPDNFSTPVGARVDRQSVRRSLIAPSSPGPQASLAQNRSPVSKEESTVRRSSRRIARKAAKEPTASARIICHSYLERLLNVEVPQKVSAPCSASSPKEEEPSKEAEPEEAAEPEVPKNNGGALQLRSTTNITLSPPSSQPAASSQEAETDQADGPKEPPQSVRRKRSYKQAVNELDEEQQLEDEELQPPRSKTPSPPCPSSKVVRPLRTFLHTVQRNQMLMTPTSTPHGNIMKSFIKRNTPLRVDPKEKERQRLENLRRKEEAEQLRRQKVEEDKRRRLEEVKLKREERLRKVLQARERVEQMKEEKKKQIEQKFAQIDEKTEKAKEERLAEEKARKKAAAKKMEEVEARRKQEEEARRLKWLQQEEEERRHQELLQKRREEEQERLRKAAEARRLAEQREQERQLAEQREQERKREQERLQAERELQEREKALRLQKERLQRELEEKKRKEEQQRLAEQRLQEEQEKKAKEAAAASNSLNVTVDVQSPACTSYQMTPQGHRAPPKINADDYGMDLNSDDSTDDEAHPRKPIPSWARGTQLSQAVIRQYYQPPDLLDLFGSLLQLDLEEIFQKSKPRYHKRTSSAVWNSPPLQGPQGPWQPGLQPEEALSQPAGRSTISASVCVCLSSSLLTYCPPAWYPVTEGLVRCI", "length": 925, "header": "tr|A0AAA9TVV0-1|A0AAA9TVV0_BOVIN Isoform 1 of Inner centromere protein OS=Bos taurus OX=9913 GN=INCENP PE=3 SV=2 CANONICAL=A0AAA9TVV0-1" }, "isoforms": [ { "isoform_ac": "A0A3Q1MAP0-1", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1MAP0/entry", "sequence": { "sequence": "MGTTAQGPIHLLELCDQKLLEFVCNVDNKDMLWLEEIEEEAQRMFTREFSKEPELMPRTPSQKNRRKKRRISSTQDENRDPVRKRLSRRKTRSSQRISRHLRSKDKVEKLATVVGENGSVLQRVTRAAAAAAAASVATAPPSPTCRSPTVLTKNPKESPTQCQLVPAVEIGASERRSAEQHLNHLQSAQAPTSTLAPASHIPSSSDEDSTPQKAEAGRLESVTVSSLMTTPRDPKGRGAGAGRSASKLRIAAAAPGPQDSPSSPASPWRERVLAPLQPDNFSTPVGARVDRQSVRRSLIAPSSPGPQASLAQNRSPVSKEESTVRRSSRRIARKAAKEPTASARIICHSYLERLLNVEVPQKVSPKEEEPSKEAEPEEAAEPEVPKNNGGALQLRSTTNITLSPPSSQPAASSQEAETDQADGPKEPPQSVRRKRSYKQAVNELDEEQQLEDEELQPPRSKTPSPPCPSSKVVRPLRTFLHTVQRNQMLMTPTSTPHGNIMKSFIKRNTPLRVDPKEKERQRLENLRRKEEAEQLRRQKVEEDKRRRLEEVKLKREERLRKVLQARERVEQMKEEKKKQIEQKFAQIDEKTEKAKEERLAEEKARKKAAAKKMEEEARRLKWLQQEEEERRHQELLQKRREEEQERLRKAAEARRLAEQREQERQLAEQREQERKREQERLQAERELQEREKALRLQKERLQRELEEKKRKEEQQRLAEQRLQEEQEKKAKEAAAASNSLNVTVDVQSPACTSYQMTPQGHRAPPKINADDYGMDLNSDDSTDDEAHPRKPIPSWARGTQLSQAVIRQYYQPPDLLDLFGSLLQLDLEEIFQKSKPRYHKRTSSAVWNSPPLQGPQGPWQPGLQPEEALSQPAGRSTISASVCVCLSSSLLTYCPPAWYPVTEGLVRCI", "length": 909, "header": "tr|A0A3Q1MAP0-1|A0A3Q1MAP0_BOVIN Computationally mapped isoform of Inner centromere protein OS=Bos taurus OX=9913 GN=INCENP PE=3 SV=2 CANONICAL=A0AAA9TVV0-1" }, "locus": { "chromosome": "29", "start_pos": 40631278, "end_pos": 40599706, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000081145.3", "url": "https://www.ensembl.org/id/ENSBTAT00000081145.3" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000065658.2", "url": "https://www.ensembl.org/id/ENSBTAP00000065658.2" } ] } }, { "isoform_ac": "A0AAA9S8B8-1", "url": "https://www.uniprot.org/uniprotkb/A0AAA9S8B8/entry", "sequence": { "sequence": "MGTTAQGPIHLLELCDQKLLEFVCNVDNKDMLWLEEIEEEAQRMFTREFSKEPELMPRTPSQKNRRKKRRISSTQDENRDPVRKRLSRRKTRSSQRISRHLRSKDKVEKLATVVGENGSVLQRVTRAAAAAAAASVATAPPSPTCRSPTVLTKNPKESPTQCQLVPAVEIGASERRSAEQHLNHLQSAQAPTSTLAPASHIPSSSDEDSTPQKAEAGRLESVTVSSLMTTPRDPKGRGAGAGRSASKLRIAAAAPGPQDSPSSPASPWRERVLAPLQPDNFSTPVGARVDRQSVRRSLIAPSSPGPQASLAQNRSPVSKEESTVRRSSRRIARKAAKEPTASARIICHSYLERLLNVEVPQKVSPKEEEPSKEAEPEEAAEPEVPKNNGGALQLRSTTNITLSPPSSQPAASSQEAETDQADGPKEPPQSVRRKRSYKQAVNELDEEQQLEDEELQPPRSKTPSPPCPSSKVVRPLRTFLHTVQRNQMLMTPTSTPHGNIMKSFIKRNTPLRVDPKEKERQRLENLRRKEEAEQLRRQKVEEDKRRRLEEVKLKREERLRKVLQARERVEQMKEEKKKQIEQKFAQIDEKTEKEEEERRHQELLQKRREEEQERLRKAAEARRLAEQREQERQLAEQREQERKREQERLQAERELQEREKALRLQKERLQRELEEKKRKEEQQRLAEQRLQEEQEKKAKEAAAASNSLNVTVDVQSPACTSYQMTPQGHRAPPKINADDYGMDLNSDDSTDDEAHPRKPIPSWARGTQLSQAVIRQYYQPPDLLDLFGSLLQLDLEEIFQKSKPRYHKRTSSAVWNSPPLQGPQGPWQPGLQPEEALSQPAGRSTISASVCVCLSSSLLTYCPPAWYPVTEGLVRCI", "length": 877, "header": "tr|A0AAA9S8B8-1|A0AAA9TVV0_BOVIN Computationally mapped isoform of Inner centromere protein OS=Bos taurus OX=9913 GN=INCENP PE=3 SV=1 CANONICAL=A0AAA9TVV0-1" }, "locus": { "chromosome": "29", "start_pos": 40631278, "end_pos": 40599706, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000099516.2", "url": "https://www.ensembl.org/id/ENSBTAT00000099516.2" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000078398.1", "url": "https://www.ensembl.org/id/ENSBTAP00000078398.1" } ] } }, { "isoform_ac": "A0AAA9TVV0-1", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TVV0/entry", "sequence": { "sequence": "MGTTAQGPIHLLELCDQKLLEFVCNVDNKDMLWLEEIEEEAQRMFTREFSKEPELMPRTPSQKNRRKKRRISSTQDENRDPVRKRLSRRKTRSSQRISRHLRSKDKVEKLATVVGENGSVLQRVTRAAAAAAAASVATAPPSPTCRSPTVLTKNPKESPTQCQLVPAVEIGASERRSAEQHLNHLQSAQAPTSTLAPASHIPSSSDEDSTPQKAEAGRLESVTVSSLMTTPRDPKGRGAGAGRSASKLRIAAAAPGPQDSPSSPASPWRERVLAPLQPDNFSTPVGARVDRQSVRRSLIAPSSPGPQASLAQNRSPVSKEESTVRRSSRRIARKAAKEPTASARIICHSYLERLLNVEVPQKVSAPCSASSPKEEEPSKEAEPEEAAEPEVPKNNGGALQLRSTTNITLSPPSSQPAASSQEAETDQADGPKEPPQSVRRKRSYKQAVNELDEEQQLEDEELQPPRSKTPSPPCPSSKVVRPLRTFLHTVQRNQMLMTPTSTPHGNIMKSFIKRNTPLRVDPKEKERQRLENLRRKEEAEQLRRQKVEEDKRRRLEEVKLKREERLRKVLQARERVEQMKEEKKKQIEQKFAQIDEKTEKAKEERLAEEKARKKAAAKKMEEVEARRKQEEEARRLKWLQQEEEERRHQELLQKRREEEQERLRKAAEARRLAEQREQERQLAEQREQERKREQERLQAERELQEREKALRLQKERLQRELEEKKRKEEQQRLAEQRLQEEQEKKAKEAAAASNSLNVTVDVQSPACTSYQMTPQGHRAPPKINADDYGMDLNSDDSTDDEAHPRKPIPSWARGTQLSQAVIRQYYQPPDLLDLFGSLLQLDLEEIFQKSKPRYHKRTSSAVWNSPPLQGPQGPWQPGLQPEEALSQPAGRSTISASVCVCLSSSLLTYCPPAWYPVTEGLVRCI", "length": 925, "header": "tr|A0AAA9TVV0-1|A0AAA9TVV0_BOVIN Isoform 1 of Inner centromere protein OS=Bos taurus OX=9913 GN=INCENP PE=3 SV=2 CANONICAL=A0AAA9TVV0-1" }, "locus": { "chromosome": "29", "start_pos": 40631278, "end_pos": 40599706, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000108756.2", "url": "https://www.ensembl.org/id/ENSBTAT00000108756.2" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000100726.2", "url": "https://www.ensembl.org/id/ENSBTAP00000100726.2" } ] } }, { "isoform_ac": "A0AAA9TW12-1", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TW12/entry", "sequence": { "sequence": "MGTTAQGPIHLLELCDQKLLEFVCNVDNKDMLWLEEIEEEAQRMFTREFSKEPELMPRTPSQKNRRKKRRISSTQDENRDPVRKRLSRRKTRSSQRISRHLRSKDKVEKLATVVGENGSVLQRVTRAAAAAAAASVATAPPSPTCRSPTVLTKNPKESPTQCQLVPAVEIGASERRSAEQHLNHLQSAQAPTSTLAPASHIPSSSDEDSTPQKAEAGRLESVTVSSLMTTPRDPKGRGAGAGRSASKLRIAAAAPGPQDSPSSPASPWRERVLAPLQPDNFSTPVGARVDRQSVRRSLIAPSSPGPQASLAQNRSPVSKEESTVRRSSRRIARKAAKEPTASARIICHSYLERLLNVEVPQKVSPKEEEPSKEAEPEEAAEPEVPKNNGGALQLRSTTNITLSPPSSQPAASSQEAETDQADGPKEPPQSVRRKRSYKQAVNELDEEQQLEDEELQPPRSKTPSPPCPSSKVVRPLRTFLHTVQRNQMLMTPTSTPHGNIMKSFIKRNTPLRVDPKSSFVEKERQRLENLRRKEEAEQLRRQKVEEDKRRRLEEVKLKREERLRKVLQARERVEQMKEEKKKQIEQKFAQIDEKTEKAKEERLAEEKARKKAAAKKMEEVEARRKQEEEARRLKWLQQEEEERRHQELLQKRREEEQERLRKAAEARRLAEQREQERQLAEQREQERKREQERLQAERELQEREKALRLQKERLQRELEEKKRKEEQQRLAEQRLQEEQEKKAKEAAAASNSLNVTVDVQSPACTSYQMTPQGHRAPPKINADDYGMDLNSDDSTDDEAHPRKPIPSWARGTQLSQAVIRQYYQPPDLLDLFGSLLQLDLEEIFQKSKPRYHKRTSSAVWNSPPLQGPQGPWQPGLQPEEALSQPAGRSTISASVCVCLSSSLLTYCPPAWYPVTEGLVRCI", "length": 922, "header": "tr|A0AAA9TW12-1|A0AAA9TW12_BOVIN Computationally mapped isoform of Inner centromere protein OS=Bos taurus OX=9913 GN=INCENP PE=3 SV=2 CANONICAL=A0AAA9TVV0-1" }, "locus": { "chromosome": "29", "start_pos": 40631278, "end_pos": 40599706, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000105140.2", "url": "https://www.ensembl.org/id/ENSBTAT00000105140.2" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000102806.2", "url": "https://www.ensembl.org/id/ENSBTAP00000102806.2" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [ { "id": "R-BTA-141430", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-BTA-141430", "resource": "Reactome", "description": "Inactivation of APC/C via direct inhibition of the APC/C complex" }, { "id": "R-BTA-141444", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-BTA-141444", "resource": "Reactome", "description": "Amplification of signal from unattached kinetochores via a MAD2 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"length": 1081, "header": "tr|A0AAA9SWM1-1|A0AAA9TTV6_BOVIN Computationally mapped isoform of SMC5-SMC6 complex localization factor protein 1 OS=Bos taurus OX=9913 GN=SLF1 PE=4 SV=1 CANONICAL=A0AAA9TTV6-1" }, "locus": { "chromosome": "7", "start_pos": 94017970, "end_pos": 93962761, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000131380.1", "url": "https://www.ensembl.org/id/ENSBTAT00000131380.1" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000087634.1", "url": "https://www.ensembl.org/id/ENSBTAP00000087634.1" } ] } }, { "isoform_ac": "A0AAA9TTV6-1", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TTV6/entry", "sequence": { "sequence": "MIKMLHGVSGGRKYQVQEATQKKIITHQSPNLRRGASRSLARESGSSRGTCLEDPDDSSRASLTTTRKCHNRFRSRGARGGKLFPRARIREATGAAAAVFVPPVRGRSAEAAAPETPAGKMEDDAPKHIIQMTGFKVEEKEALGKLLLKLDCTFIKSEKYKNCTHLIAERLCKSEKFLAACAAGKWVLTKDYIIHSAQSGRWLDETTYEWGYKIEKDSHYSPQMQSAPKRWREELKRTGAPGAFHKWKVVLLVRADKRSDSLVRVLEAGKANVILPKNSPTGITHVIASNARIKAEQEKDDFKAPFYPIQYLEDFLLEKEIHNDEDSQTNSTWKNHSSQEKSNDFRENMGFLEMKGTLKETMCRTQKEMKNHDEDVTISSILTEHQSKERFRDSRKNLKFVKMRNALGRHTYRNQEMKKKDEDIQSIYTLRKKRKKEKERDSRKDIEHDRSTLRKHIYRDQKERKNSVFAGHAKESKTKDIRTNVDIVDLKNALRKHIYRAQAVRYRGIRIDKQPAYNVEVKNAEFPRGILNLIESLIEGQFFKEAIEELSSLQAHYIPPVYLLHALLENILQDNIDTFSGRYFHILSALLHLHPPWKSPAMSTYYLELFQCPTCMKGTWSLIEVLIRSCLFNESFCHQISENIIGSKVLHLTLLKFFFNLIESEVRHLSQKLYDWSDSQSLKITGKAVLLEIFWSGNETSGLLTKPVNMLLEWTIYSHKEKCKSNDVFRHELAYLLTGILGAAIDYWIVLGLNMGRNVMRHMSDDVGSYVSLSCDDFSSQDLEIFISSFSSSWLQMFVAEAVFKKLCLQNSISISSEPLSLQKMVYSYLPALGKTGVRGTRKMQKPKKIGLRPCFESQRALIMLNGAKQKQGEGLPEIPELNLAKCSSSLKRLKKKSEGELSCSKENCPSLVTKINFHKTNLKGETALHRACINNQVDRLILLLSMPGIDINVKDNAGWTPLHEACNYGNTVCVQEILQRCPEVDLLTQVDGVTPLHDALSNGHVEIGKLLLQHGGPVLLQQRNSKGELPLDYVVSSQIKEELFAITKIEDTVENFHAQAEKHFYHQQLEFGSFLLSRMLLNFCSIFGLSSESLAFKGLTHLSELLIACQNYKETTSVHTDWLLDLYARNIMTLQKLPNALKELPENVKVCPGVHTEALLVTLEVMCRSVTEIS", "length": 1175, "header": "tr|A0AAA9TTV6-1|A0AAA9TTV6_BOVIN Isoform 1 of SMC5-SMC6 complex localization factor protein 1 OS=Bos taurus OX=9913 GN=SLF1 PE=4 SV=1 CANONICAL=A0AAA9TTV6-1" }, "locus": { "chromosome": "7", "start_pos": 94017970, "end_pos": 93949895, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000091395.1", "url": "https://www.ensembl.org/id/ENSBTAT00000091395.1" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000099971.1", "url": "https://www.ensembl.org/id/ENSBTAP00000099971.1" } ] } }, { "isoform_ac": "A0AAF6YPK3-1", "url": "https://www.uniprot.org/uniprotkb/A0AAF6YPK3/entry", "sequence": { "sequence": "MEDDAPKHIIQMTGFKVEEKEALGKLLLKLDCTFIKSEKYKNCTHLIAERLCKSEKFLAACAAGKWVLTKDYIIHSAQSGRWLDETTYEWGYKIEKDSHYSPQMQSAPKRWREELKRTGAPGAFHKWKVVLLVRADKRSDSLVRVLEAGKANVILPKNSPTGITHVIASNARIKAEQEKDDFKAPFYPIQYLEDFLLEHLPTWYTYHSLSCLNGNNPRRIALKKEIHNDEDSQTNSTWKNHSSQEKSNDFRENMGFLEMKGTLKETMCRTQKEMKNHDEDVTISSILTEHQSKERFRDSRKNLKFVKMRNALGRHTYRNQEMKKKDEDIQSIYTLRKKRKKEKERDSRKDIEHDRSTLRKHIYRDQKERKNSVFAGHAKESKTKDIRTNVDIVDLKNALRKHIYRAQAVRYRGIRIDKQPAYNVEVKNAEFPRGILNLIESLIEGQFFKEAIEELSSLQAHYIPPVYLLHALLENILQDNIDTFSGRYFHILSALLHLHPPWKSPAMSTYYLELFQCPTCMKGTWSLIEVLIRSCLFNESFCHQISENIIGSKVLHLTLLKFFFNLIESEVRHLSQKLYDWSDSQSLKITGKAVLLEIFWSGNETSGLLTKPVNMLLEWTIYSHKEKCKSNDVFRHELAYLLTGILGAAIDYWIVLGLNMGRNVMRHMSDDVGSYVSLSCDDFSSQDLEIFISSFSSSWLQMFVAEAVFKKLCLQNSISISSEPLSLQKMVYSYLPALGKTGVRGTRKMQKPKKIGLRPCFESQRALIMLNGAKQKQGEGLPEIPELNLAKCSSSLKRLKKKSEGELSCSKENCPSLVTKINFHKTNLKGETALHRACINNQVDRLILLLSMPGIDINVKDNAGWTPLHEACNYGNTVCVQEILQRCPEVDLLTQVDGVTPLHDALSNGHVEIGKLLLQHGGPVLLQQRNSKGELPLDYVVSSQIKEELFAITKIEDTVENFHAQAEKHFYHQQLEFGSFLLSRMLLNFCSIFGLSSESLAFKGLTHLSELLIACQNYKETTSVHTDWLLDLYARNIMTLQKLPNALKELPENVKVCPGVHTEALLVTLEVMCRSVTEIS", "length": 1080, "header": "tr|A0AAF6YPK3-1|A0AAF6YPK3_BOVIN Computationally mapped isoform of SMC5-SMC6 complex localization factor protein 1 OS=Bos taurus OX=9913 GN=SLF1 PE=4 SV=1 CANONICAL=A0AAA9TTV6-1" }, "locus": { "chromosome": "7", "start_pos": 94017970, "end_pos": 93962761, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000008026.7", "url": "https://www.ensembl.org/id/ENSBTAT00000008026.7" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000008026.7", "url": "https://www.ensembl.org/id/ENSBTAP00000008026.7" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [], "orthologs": [], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 7, "go_terms": [ { "name": "nucleus", "id": "GO:0005634", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005634", "evidence": [ { "database": "UniProtKB", "id": "A0AAA9TTV6", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TTV6" } ], "pmid": "" }, { "name": "centrosome", "id": "GO:0005813", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005813", "evidence": [ { "database": "UniProtKB", "id": "A0AAA9TTV6", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TTV6" } ], "pmid": "" }, { "name": "chromosome", "id": "GO:0005694", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005694", "evidence": [ { "database": "UniProtKB", "id": "A0AAA9TTV6", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TTV6" } ], "pmid": "" }, { "name": "cytoplasm", "id": "GO:0005737", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005737", "evidence": [ { "database": "UniProtKB", "id": "A0AAA9TTV6", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TTV6" } ], "pmid": "" }, { "name": "site of double-strand break", "id": "GO:0035861", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0035861", "evidence": [ { "database": "UniProtKB", "id": "A0AAA9TTV6", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TTV6" } ], "pmid": "" }, { "name": "nuclear inclusion body", "id": "GO:0042405", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0042405", "evidence": [ { "database": "UniProtKB", "id": "A0AAA9TTV6", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TTV6" } ], "pmid": "" }, { "name": "nucleosome", "id": "GO:0000786", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000786", "evidence": [ { "database": "UniProtKB", "id": "A0AAA9TTV6", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TTV6" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 5, "go_terms": [ { "name": "DNA repair", "id": "GO:0006281", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006281", "evidence": [ { "database": "UniProtKB", "id": "A0AAA9TTV6", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TTV6" } ], "pmid": "" }, { "name": "positive regulation of double-strand break repair", "id": "GO:2000781", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:2000781", "evidence": [ { "database": "UniProtKB", "id": "A0AAA9TTV6", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TTV6" } ], "pmid": "" }, { "name": "protein localization to site of double-strand break", "id": "GO:1990166", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:1990166", "evidence": [ { "database": "UniProtKB", "id": "A0AAA9TTV6", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TTV6" } ], "pmid": "" }, { "name": "positive regulation of protein-containing complex assembly", "id": "GO:0031334", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0031334", "evidence": [ { "database": "UniProtKB", "id": "A0AAA9TTV6", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TTV6" } ], "pmid": "" }, { "name": "positive regulation of maintenance of mitotic sister chromatid cohesion", "id": "GO:0034184", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0034184", "evidence": [ { "database": "UniProtKB", "id": "A0AAA9TTV6", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TTV6" } ], "pmid": "" } ] }, { "name": "Molecular Function", "total": 2, "go_terms": [ { "name": "ubiquitin protein ligase binding", "id": "GO:0031625", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0031625", "evidence": [ { "database": "UniProtKB", "id": "A0AAA9TTV6", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TTV6" } ], "pmid": "" }, { "name": "protein-containing complex binding", "id": "GO:0044877", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0044877", "evidence": [ { "database": "UniProtKB", "id": "A0AAA9TTV6", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TTV6" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 162, "end_pos": 164, "annotation": "n_glycosylation_sequon" }, { "start_pos": 330, "end_pos": 332, "annotation": "n_glycosylation_sequon" }, { "start_pos": 335, "end_pos": 337, "annotation": "n_glycosylation_sequon" }, { "start_pos": 633, "end_pos": 635, "annotation": "n_glycosylation_sequon" }, { "start_pos": 698, "end_pos": 700, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], 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633, "end_pos": 635 }, { "start_pos": 698, "end_pos": 700 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": 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"evidence": [ { "database": "UniProtKB", "id": "A0AAA9TTA4", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TTA4" } ], "common_name": "Bovine", "glygen_name": "Bovine", "reference_species": "Bos taurus [9913]" } ], "gene": [ { "name": "FAM234B", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TTA4", "locus": { "chromosome": "5", "start_pos": 96786862, "end_pos": 96866428, "strand": "+", "evidence": [ { "database": "Ensembl Gene", "id": "ENSBTAG00000014322", "url": "https://www.ensembl.org/id/ENSBTAG00000014322" } ] } } ], "crossref": [ { "id": "A0AAA9TTA4", "url": "https://alphafold.ebi.ac.uk/entry/A0AAA9TTA4", "database": "AlphaFoldDB", "categories": [] }, { "id": "ENSBTAG00000014322", "url": "https://bgee.org/?page=gene&gene_id=ENSBTAG00000014322", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "512120", "url": "https://www.ncbi.nlm.nih.gov/gene/512120", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR011047", "url": 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] }, { "id": "PTHR21419:SF25", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR21419:SF25", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF23727", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF23727", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "XP_002687827", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_002687827", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0AAA9SC69", "url": "https://www.uniprot.org/uniprotkb/A0AAA9SC69", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0AAA9SC69-1", "url": "https://www.uniprot.org/uniprotkb/A0AAA9SC69-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0AAA9TTA4", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TTA4", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0AAA9TTA4-1", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TTA4-1", "database": "UniProtKB", "categories": [ 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Family with sequence similarity 234 member B OS=Bos taurus OX=9913 GN=FAM234B PE=3 SV=1 CANONICAL=A0AAA9TTA4-1" }, "isoforms": [ { "isoform_ac": "A0AAA9SC69-1", "url": "https://www.uniprot.org/uniprotkb/A0AAA9SC69/entry", "sequence": { "sequence": "MKGKKSPDLGEYDPLTQADSDESEDDLVLNLQQKNGGVKNGKSPLGEAPEPDSDAEVAGAGKPRLSEVTPEGYPLEPLGALEQKAASSVVSCVRTSVFLLMLVVSMVLVLVCAFLIPCPPRDLHSTWSRHLGPQGGGDLSPLDLADVNGDGLRDVLLSFVPAGNGSAAGVSRPPAVLVCLSGMNGSTLWSSPLPEEARDITCLDLTPGNMAKTVCLVTGTHKMLSAFNGTSGKAMWTLNPNYLSNGTLAAPAVVLPDVDEDGVRDLAVLAIGELQPDLCFLLVSGRTGSPVGRPVKYNIVGVGNLIGPQVYITTSGAAYILFGFGNIQAVALRDIFVQAQNRDSLPPSLQIEEPEWEKRRSVNLSELIDVYSDGVELLQMVKAPDSNSSNLLITTTQGLVLLRGQNLTPSWVLGLQGLHSQPTPGYFTDDETIDFLLQIPNGVGMKKVMVVDGDSGLVTWSYSIPCHMKETPATSAATVEQKSVFLFWAEGLSAASPNPDVVLGTEPPSLHHLYLLHPTFPSILLDLANATGTVTASEVGINDLWKDAFYVTRTTGPSSEGHPAPLVVSKLSLRWALMEGQMVQLEETTPKIGRGELRRFLSRIKFVDSPYQI", "length": 613, "header": "tr|A0AAA9SC69-1|A0AAA9TTA4_BOVIN Computationally mapped isoform of Family with sequence similarity 234 member B OS=Bos taurus OX=9913 GN=FAM234B PE=3 SV=1 CANONICAL=A0AAA9TTA4-1" }, "locus": { "chromosome": "5", "start_pos": 96862535, "end_pos": 96789745, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000099185.1", "url": "https://www.ensembl.org/id/ENSBTAT00000099185.1" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000081476.1", "url": "https://www.ensembl.org/id/ENSBTAP00000081476.1" } ] } }, { "isoform_ac": "A0AAA9TTA4-1", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TTA4/entry", "sequence": { "sequence": "MATVLSRALKLPGKKSPDLGEYDPLTQADSDESEDDLVLNLQQKNGGVKNGKSPLGEAPEPDSDAEVAGAGKPRLSEVTPEGYPLEPLGALEQKAASSVVSCVRTSVFLLMLVVSMVLVLVCAFLIPCPPRDLHSTWSRHLGPQGGGDLSPLDLADVNGDGLRDVLLSFVPAGNGSAAGVSRPPAVLVCLSGMNGSTLWSSPLPEEARDITCLDLTPGNMAKTVCLVTGTHKMLSAFNGTSGKAMWTLNPNYLSNGTLAAPAVVLPDVDEDGVRDLAVLAIGELQPDLCFLLVSGRTGSPVGRPVKYNIVGVGNLIGPQVYITTSGAAYILFGFGNIQAVALRDIFVQAQNRDSLPPSLQIEEPEWEKRRSVNLSELIDVYSDGVELLQMVKAPDSNSSNLLITTTQGLVLLRGQNLTPSWVLGLQGLHSQPTPGYFTDDETIDFLLQIPNGVGMKKVMVVDGDSGLVTWSYSIPCHMKETPATSAATVEQKSVFLFWAEGLSAASPNPDVVLGTEPPSLHHLYLLHPTFPSILLDLANATGTVTASEVGINDLWKDAFYVTRTTGPSSEGHPAPLVVSKLSLRWALMEGQMVQLEETTPKIGRGELRRFLSRIKFVDSPYQI", "length": 623, "header": "tr|A0AAA9TTA4-1|A0AAA9TTA4_BOVIN Isoform 1 of Family with sequence similarity 234 member B OS=Bos taurus OX=9913 GN=FAM234B PE=3 SV=1 CANONICAL=A0AAA9TTA4-1" }, "locus": { "chromosome": "5", "start_pos": 96826659, "end_pos": 96789745, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000124800.1", "url": "https://www.ensembl.org/id/ENSBTAT00000124800.1" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000100574.1", "url": "https://www.ensembl.org/id/ENSBTAP00000100574.1" } ] } }, { "isoform_ac": "F1N5E1-1", "url": "https://www.uniprot.org/uniprotkb/F1N5E1/entry", "sequence": { "sequence": "MATVLSRALKLPGKKSPDLGEYDPLTQADSDESEDDLVLNLQQKNGGVKNGKSPLGEAPEPDSDAEVAGAGKPRLSEVTPEGYPLEPLGALEQKAASSVVSCVRTSVFLLMLVVSMVLVLVCAFLIPCPPRDLHSTWSRHLGPQGGGDLSPLDLADVNGDGLRDVLLSFVPAGNGSAAGVSRPPAVLVCLSGMNGSTLWSSPLPEEARDITCLDLTPGNMAKTVCLVTGTHKMLSAFNGTSGKAMWTLNPNYLSNGTLAAPAVVLPDVDEDGVRDLAVLAIGELQPDLCFLLVSGRTGSPVGRPVKYNIVGVGNLIGPQVYITTSGAAYILFGFGNIQAVALRDIFVQAQNRDSLPPSLQIEEPEWEKRRSVNLSELIDVYSDGVELLQMVKAPDSNSSNLLITTTQGLVLLRGQNLTPSWVLGLQGLHSQPTPGYFTDDETIDFLLQIPNGVGMKKVMVVDGDSGLVTWSYSIPCHMKETPATSAATVEQKSVFLFWAEGLSAASPNPDVVLGTEPPSLHHLYLLHPTFPSILLDLANATGTVTASEVGINDLWKDAFYVTRTTGPSSEGHPAPLVVSKLSLRWALMEGQMVQLEETTPKIGRGELRRFLSRIKSRLLDSAVPEEVNGVSLSLPSGCKHNSLERRTSVTPFHLLCVTIARHLERHLEFFGNPLTRRLRQEGLLSSPELHLGCQQSPSTTT", "length": 701, "header": "tr|F1N5E1-1|F1N5E1_BOVIN Computationally mapped isoform of Family with sequence similarity 234 member B OS=Bos taurus OX=9913 GN=FAM234B PE=3 SV=3 CANONICAL=A0AAA9TTA4-1" }, "locus": { "chromosome": "5", "start_pos": 96826659, "end_pos": 96786962, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000019045.6", "url": "https://www.ensembl.org/id/ENSBTAT00000019045.6" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000019045.6", "url": "https://www.ensembl.org/id/ENSBTAP00000019045.6" } ] } } ], "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "other", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 433, "start_aa": "Thr", "end_pos": 433, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr433", "evidence": [ { "id": "", "database": "GlyGen", "url": "https://data.glygen.org/" } ], "filter_code": "000000000000000010000.00000000001000.0.01000" } ], "phosphorylation": [], "glycation": [], "keywords": [ "glycoprotein", "glycoprotein_predicted" ], "publication": [], "pathway": [ { "id": "bta:512120", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?bta:512120", "resource": "KEGG Pathway" } ], "orthologs": [ { "uniprot_canonical_ac": "A0A286ZWF4-1", "protein_name": "Family with sequence similarity 234 member B", "gene_name": "FAM234B", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MATVLSRALKLPGKKSPDLGEYDPLTQADSDESEDDLVLNLQQKNGGVKNGQSPLGEAPEPDSDAEPAGSAKPHLSEVTTEGYPLEPLGGLEQKAASSMASYVRTSVFLLMLVVSTVLVLVCAFLIPCPPRDLHSTWSRRLGPQGGGDLNPLELADVNGDGLRDVLLSFVTLRNGSTAGVSRPPALLVCLSGMNGSTLWSSPLPEEARDVTCLDLMPGSGAGTVCLVTGTHKMLSAFNGTSGKAIWTLNPNYLSNGTLAAPGVMLPDLDEDGVRDLVVLAIGEVQPDLCFLLVSGRTGSPVGRPVKYSIVGVGNLIGPQVYITASGAVYILFGFGNIQAVALRDIFVQAQNRDSSPPSLQIEEPEWEKRRSINLSELIDVYSYGVELLQMVKAADSNCSNLLITTRQGLVLLRGQNLTPSWTLSLQGLRSQPTPGYFTDDETLDFLLQIPSGTGMKKVMVVDGDSGLVTWSYSVPCRMRETPTTSAATVDQKSVFLFWAEGLSAPSPSSDVTLGTEAPDLHHLYLLHPAFPSILLDLANATGTVTASEVGINDLWKDAFYVTRTTGPSSEGHPAPLVVSKLSLRWALMEGQVVQLKETTPKIGRGELRRFLSRIKFVDSPYQM", "length": 623 }, "evidence": [ { "id": "A0AAA9TTA4", "url": "https://omabrowser.org/oma/group/A0AAA9TTA4/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "A2RU67-1", "protein_name": "Protein FAM234B", "gene_name": "FAM234B", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MATVLSRALKLPGKKSPDLGEYDPLTQADSDESEDDLVLNLQKNGGVKNGKSPLGEAPEPDSDAEVAEAAKPHLSEVTTEGYPSEPLGGLEQKAASSLVSYVRTSVFLLTLGISMILVLLCAFLIPCPPRDLHSTWSRHLGSQGGGDLSPLELADVNGDGLRDVLLSFVMSRNGSAVGVSRPAANLVCLSGMNGSTLWSSLLPEEARDITCLELMPGSLAETICLVTGTHKMLSAFNATSGKAIWTLNPNYLSNGTLAAPVVVLPDLDEDGVRDLVVLAIGELQPDLCFLLVSGRTGNPVGRPVKYNIVGVGNLIGPQVYITTNGAVYILFGFGNIQAVALRDIFVQAQNRDSSPPSLQIEEPEWEKRRSINLSELIDVYSDGVELLQMVKAPDSNCSNLLITTRQSLVLLRGQNLTPYWALRLQGLRSQPTPGYFTDDQTLDFLLQIQDGVGMKKMMVVDGDSGSIVWSYRAPCHMKETPATSAVTSDQKSVFLFWAEGLSAASPNSDIILGTEPPSLHHLYLLHPAFPSILLDLANTTGTVTASEVGINDLWKDAFYVTRTTGPSSEGHPAALVVSKLSLRWALMEGQMAQLQESTPKIGRGELRRFLSRIKFVEAPYEI", "length": 622 }, "evidence": [ { "id": "A0AAA9TTA4", "url": "https://omabrowser.org/oma/group/A0AAA9TTA4/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "D3ZWJ9-1", "protein_name": "Protein FAM234B", "gene_name": "Fam234b", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MATVLSRALKLPGKKSPDLGEYDPLTQADSDESEDDLVLNLQQKNGGVKNGKSALGDPPEPDSDADVAGASKPHLSEVTPEGFPSEPLGGLEQKATSSLVSYVRTSVFLLTLVISMVLVLLCAFLIPCPPRDLHSTWSRRLGSQGGGDLSPLELADVNRDGLRDVLLTFVTTRNGTEGGGGSQPTADLVCLSGMNGSTLWSSPLPEEAQDVTCLDLIPGSVAKTICLVTGTRKMLSAFNATSGKILWTLNPNYLSNGTLAAPVVVLPDLDEDGVRDLVVLAIGELQPDLCFLLVSGRTGSPVGRPVKYNIVGVGNLIGPQVYITASGAVYILFGFGNIQAVALRDIFVQAQNRDSSPPSLQIEEPEWEKHRSVNLSELIDVYSDGVELLQLVKAPDSNSSSLLITTRQGLVLLRGQDLTPHWKLNLQGLRSQPTPGYFTDDQTLDFLLQTQDGVGMKKMTVVDGSSGSIVWSYRVPCHVKETPTTSAITSDQKSVFLFWAEALTAASLSSDDSSGAEPSGLYHLYLLHPAFPSVLLDLSNTTGIVTAAEVGVNDIWKDAFYVTRTTGMSPEGHTTSLVVSKLSLRWGLMEGQMVQLKETTPKIGRGELRRFLSRIKFVDSPYQM", "length": 624 }, "evidence": [ { "id": "A0AAA9TTA4", "url": "https://omabrowser.org/oma/group/A0AAA9TTA4/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "Q5F3L3-1", "protein_name": "Protein FAM234B", "gene_name": "FAM234B", "tax_id": 9031, "organism": "Gallus gallus", "sequence": { "sequence": "MATVLSRALKLPGKKSPDLGEYDPLTQADSDESEDDLVLNIQKNGGVKNGKSPPEEMQDPDSDVEVGMTKQHTSERAPEGYPAEAAGSLEQKAAPSLMPYLRTAVFLLTVVISMILVLVCAFLIPCPPRDLHNTWNHNLGQGAGGVLSPLELCDVNGDGLPDILIVFTALMNASVMGVSTPSVTVVALSGMNGSTLWSIQLPEETRSVQCKGLSLGSPAEPICLVTGTAKFLSLLSASTGKTIWTLNSIHLSDGILAAPAATLPDVDGDGIRDIVVLALKETQPDVFFVLVSGKTGAALGGPVKYNVIGEGKVIGPQVHITSRGAIYILFGFGNVQAIALRDIFTQARNRDSFPMMLHQEEPEWEKRRSVNLSELIDIYSGGVDFLQTIKAPDTNCSNLLITTKEGLILLQGQDLEPRWTLEIQNISSQPVLGYFSADQTLDFMLQAQTGNGKKKVVVVDGKSGLPVWKQELPWQKQQLDALSVMTLDKKSVFLFWADEAQPVLHSLHPGPRSERPGLHHLYLLHPVFPTVLLDLTNATDKVIASAVGINDLQKDAFHITVTTTATSEKQPGFLSVSKLGLKWAMMTQGRMVWLKDTTTPKISRGEVRRFLARLKFVDFPHKL", "length": 623 }, "evidence": [ { "id": "A0AAA9TTA4", "url": "https://omabrowser.org/oma/group/A0AAA9TTA4/", "database": "OMA" } ], "glygen_name": "Chicken", "common_name": "Chicken" }, { "uniprot_canonical_ac": "Q8BYI8-1", "protein_name": "Protein FAM234B", "gene_name": "Fam234b", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MATVLSRALKLPGKKSPDLGEYDPLTQADSDESEDDLVLNLQQKNGGVKNGKSALGDLPEPDSDADVAGAAKPHLSEVTPEGFPSEPLGGLEQKATSPLVSYVRTSVFLLTLVISMVLVLLCAFLIPCPPRDLHSAWSRRLGSQGGGDLSPLELADVNRDGLRDVLLTFVTTRNGTEGGVGSQPTADLVCLSGMNGSTLWSSPLPEEAQDVTCLDLIPGSVAKTICLVTGTRKMLSAFNATSGKVLWTLNPNHLSNGTLAAPVVVLPDLDEDGVRDLVVLAIGELQPDLCFLLVSGRTGSPVGRPVKYNIVGVGNLIGPQVYITASGAVYILFGFGNIQAVALRDIFVQAQNRDSSPPSLQIEEPEWEKHRSVNLSELIDVYSDGVELLQLVKAPDSNSSSLLITTRQGLVLLRGQDLTPHWKLNLQGLRSQPTPGYFTDDQTLDFLLQTQDGDGMKKMTVVDGGSGSIVWSYSIPCHMKETPTTSAITSDQKSVFLFWAEALTAASLSSDDSSGAEPPGLYHLYLLHPAFPSILLDLSNTTGIVTASEVGINDIWKDAFYVTRTTGMSPEGHPTSLVVSKLSLRWALMEGQMVQLKETTPKIGRGELRRFLSRIKFVDSPYQI", "length": 624 }, "evidence": [ { "id": "A0AAA9TTA4", "url": "https://omabrowser.org/oma/group/A0AAA9TTA4/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" } ], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 1, "go_terms": [ { "name": "membrane", "id": "GO:0016020", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016020", "evidence": [ { "database": "UniProtKB", "id": "A0AAA9TTA4", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TTA4" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 174, "end_pos": 176, "annotation": "n_glycosylation_sequon" }, { "start_pos": 194, "end_pos": 196, "annotation": "n_glycosylation_sequon" }, { "start_pos": 238, "end_pos": 240, "annotation": "n_glycosylation_sequon" }, { "start_pos": 255, "end_pos": 257, "annotation": "n_glycosylation_sequon" }, { "start_pos": 373, "end_pos": 375, "annotation": "n_glycosylation_sequon" }, { "start_pos": 397, "end_pos": 399, "annotation": "n_glycosylation_sequon" }, { "start_pos": 416, "end_pos": 418, "annotation": "n_glycosylation_sequon" }, { "start_pos": 539, "end_pos": 541, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A0AAA9TTA4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TTA4" }, { "id": "PF23727", "database": "Pfam", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF23727" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "FAM234A/B beta-propeller", "eco_id": "ECO_0000259", "start_pos": 152, "end_pos": 616, "start_aa": "Leu", "end_aa": "Phe", "glycosite_overlap": [] } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" }, { "name": "homologset.oma", "label": "OMA Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [ 433 ], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 174, "end_pos": 176 }, { "start_pos": 194, "end_pos": 196 }, { "start_pos": 238, "end_pos": 240 }, { "start_pos": 255, "end_pos": 257 }, { "start_pos": 373, "end_pos": 375 }, { "start_pos": 397, "end_pos": 399 }, { "start_pos": 416, "end_pos": 418 }, { "start_pos": 539, "end_pos": 541 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 1 }, { "field": "total_sites", "count": 1 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 1 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "exact_sites", "count": 1 }, { "field": "exact_o_linked_sites", "count": 1 }, { "field": "fuzzy_sites", "count": 0 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_pos", "start_aa", "end_pos", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 1 }, { "field": "total_sites", "count": 1 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 1 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "exact_sites", "count": 1 }, { "field": "exact_o_linked_sites", "count": 1 }, { "field": "fuzzy_sites", "count": 0 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_pos", "start_aa", "end_pos", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ], "tool_support": { "graph_view": "yes" } }, { "uniprot_canonical_ac": "A0AAA9TW67-1", "uniprot_ac": "A0AAA9TW67", "uniprot_id": "A0AAA9TW67_BOVIN", "mass": { "chemical_mass": 19761.0, "monoisotopic_mass": 19761.0 }, "refseq": { "ac": "XP_005221049", "name": "proline-rich protein 29 isoform X2", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_005221049" }, "gene_names": [ { "name": "PRR29", "type": "recommended", "evidence": [ { "id": "A0AAA9TW67", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TW67" } ] }, { "name": "PRR29", "type": "synonym", "evidence": [ { "id": "XP_005221049", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_005221049" } ] } ], "protein_names": [ { "name": "Proline rich 29", "type": "synonym", "evidence": [ { "id": "A0AAA9TW67", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TW67/entry#names_and_taxonomy" } ] }, { "name": "proline-rich protein 29 isoform X2", "type": "synonym", "evidence": [ { "id": "XP_005221049", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_005221049" } ] } ], "function": [], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Bos taurus", "taxid": 9913, "evidence": [ { "database": "UniProtKB", "id": "A0AAA9TW67", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TW67" } ], "common_name": "Bovine", "glygen_name": "Bovine", "reference_species": "Bos taurus [9913]" } ], "gene": [ { "name": "PRR29", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TW67", "locus": {} } ], "crossref": [ { "id": "A0AAA9TW67", "url": "https://alphafold.ebi.ac.uk/entry/A0AAA9TW67", "database": "AlphaFoldDB", "categories": [] }, { "id": "100336106", "url": "https://www.ncbi.nlm.nih.gov/gene/100336106", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR027904", "url": "https://www.ebi.ac.uk/interpro/entry/IPR027904", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR038915", "url": "https://www.ebi.ac.uk/interpro/entry/IPR038915", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "bta:100336106", "url": "https://www.genome.jp/dbget-bin/www_bget?bta:100336106", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "PTHR28604", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR28604", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR28604:SF1", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR28604:SF1", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF15248", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF15248", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "XP_005221049", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_005221049", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0AAA9TW67", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TW67", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0AAA9TW67-1", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TW67-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0AAA9TZL7", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TZL7", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0AAA9TZL7-1", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TZL7-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MASGIGGSWSQPPAQTAAPMPWVTILQPLPWTIPPTSRQPGRVKEDLLELMMLQNVQMNQLFLSGQVAAVLNQGLSWTNPQVSLEVQHQEETEPQEEGPLVFHHHYLPCTMSALGPLLPWPGPLLSPPLHQPRVQDSAEIQHHPPAPGKRGVRAVPPPPPPSATGTVGADVPPASDYYDAESS", "length": 183, "header": "tr|A0AAA9TW67-1|A0AAA9TW67_BOVIN Isoform 1 of Proline rich 29 OS=Bos taurus OX=9913 GN=PRR29 PE=4 SV=1 CANONICAL=A0AAA9TW67-1" }, "isoforms": [ { "isoform_ac": "A0AAA9TW67-1", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TW67/entry", "sequence": { "sequence": "MASGIGGSWSQPPAQTAAPMPWVTILQPLPWTIPPTSRQPGRVKEDLLELMMLQNVQMNQLFLSGQVAAVLNQGLSWTNPQVSLEVQHQEETEPQEEGPLVFHHHYLPCTMSALGPLLPWPGPLLSPPLHQPRVQDSAEIQHHPPAPGKRGVRAVPPPPPPSATGTVGADVPPASDYYDAESS", "length": 183, "header": "tr|A0AAA9TW67-1|A0AAA9TW67_BOVIN Isoform 1 of Proline rich 29 OS=Bos taurus OX=9913 GN=PRR29 PE=4 SV=1 CANONICAL=A0AAA9TW67-1" }, "locus": { "chromosome": "19", "start_pos": 48204050, "end_pos": 48200676, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000122588.2", "url": "https://www.ensembl.org/id/ENSBTAT00000122588.2" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000102573.1", "url": "https://www.ensembl.org/id/ENSBTAP00000102573.1" } ] } }, { "isoform_ac": "A0AAA9TZL7-1", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TZL7/entry", "sequence": { "sequence": "MASGIGGSWSQPPAQTAAPMPWVTILQPLPWTIPPTSRQPGRVKEDLLELMMLQNVQMNQLFLSGQVAAVLNQGLSWTNPQESGAPTSTAQCHGNCGCRCTSSFRLLRC", "length": 109, "header": "tr|A0AAA9TZL7-1|A0AAA9TZL7_BOVIN Computationally mapped isoform of Proline rich 29 OS=Bos taurus OX=9913 GN=PRR29 PE=4 SV=1 CANONICAL=A0AAA9TW67-1" }, "locus": { "chromosome": "19", "start_pos": 48204040, "end_pos": 48200676, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000121982.2", "url": "https://www.ensembl.org/id/ENSBTAT00000121982.2" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000102717.1", "url": "https://www.ensembl.org/id/ENSBTAP00000102717.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [ { "id": "bta:100336106", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?bta:100336106", "resource": "KEGG Pathway" } ], "orthologs": [], "go_annotation": {}, "pro_annotation": [], "site_annotation": [], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A0AAA9TW67", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TW67" }, { "id": "PF15248", "database": "Pfam", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF15248" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "DUF4587", "eco_id": "ECO_0000259", "start_pos": 39, "end_pos": 106, "start_aa": "Gln", "end_aa": "Tyr", "glycosite_overlap": [] } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ], "tool_support": { "graph_view": "yes" } }, { "uniprot_canonical_ac": "A0AAA9TTJ2-1", "uniprot_ac": "A0AAA9TTJ2", "uniprot_id": "A0AAA9TTJ2_BOVIN", "mass": { "chemical_mass": 65076.0, "monoisotopic_mass": 65076.0 }, "refseq": {}, "gene_names": [ { "name": "SLC23A3", "type": "recommended", "evidence": [ { "id": "A0AAA9TTJ2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TTJ2" } ] } ], "protein_names": [ { "name": "Solute carrier family 23 member 3", "type": "synonym", "evidence": [ { "id": "A0AAA9TTJ2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TTJ2/entry#names_and_taxonomy" } ] } ], "function": [], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Bos taurus", "taxid": 9913, "evidence": [ { "database": "UniProtKB", "id": "A0AAA9TTJ2", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TTJ2" } ], "common_name": "Bovine", "glygen_name": "Bovine", "reference_species": "Bos taurus [9913]" } ], "gene": [ { "name": "SLC23A3", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TTJ2", "locus": { "chromosome": "2", "start_pos": 107113751, "end_pos": 107120508, "strand": "+", "evidence": [ { "database": "Ensembl Gene", "id": "ENSBTAG00000012618", "url": "https://www.ensembl.org/id/ENSBTAG00000012618" } ] } } ], "crossref": [ { "id": "A0AAA9TTJ2", "url": "https://alphafold.ebi.ac.uk/entry/A0AAA9TTJ2", "database": "AlphaFoldDB", "categories": [] }, { "id": "ENSBTAG00000012618", "url": "https://bgee.org/?page=gene&gene_id=ENSBTAG00000012618", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "523081", "url": "https://www.ncbi.nlm.nih.gov/gene/523081", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR006043", "url": "https://www.ebi.ac.uk/interpro/entry/IPR006043", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "bta:523081", "url": "https://www.genome.jp/dbget-bin/www_bget?bta:523081", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "LTWGLSC", "url": "https://omabrowser.org/oma/group/LTWGLSC/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "E1BEZ1", "url": "https://www.orthodb.org/?gene=E1BEZ1", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR11119", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR11119", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00860", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00860", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "A0AAA9SEJ2", "url": "https://www.uniprot.org/uniprotkb/A0AAA9SEJ2", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0AAA9SEJ2-1", "url": "https://www.uniprot.org/uniprotkb/A0AAA9SEJ2-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0AAA9TTJ2", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TTJ2", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0AAA9TTJ2-1", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TTJ2-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "E1BEZ1", "url": "https://www.uniprot.org/uniprotkb/E1BEZ1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "E1BEZ1-1", "url": "https://www.uniprot.org/uniprotkb/E1BEZ1-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MSQSPPNAIQLQSVGSQGTLATLPRPPDVQNPSSDSWASLSGPPPWGLSCLLALQHILVLASLLCASHLLLLQSLPAGGLSFSPAQLLASSLFACGVSTSLQTWMGSRLPLVQAPSLQFLIPALVLTSQKLPLALRTPGNCEHRARAQASLVLRLCGGPGCHGLELWNTSIREVSGAVVVSGLLQAILGLLGGPGHLFPRCGPLVLAPSLVVAGLSVYREVALLCSTHWGLASLLIVLMVVCSQHLGSCLLPPRHWRPASTSSTHTHILAFRLLSVLIPVACVWIVSALLGLSIIPGELSAPTKAPWFWLPHPAEWDWPLLTPRALAAGISMALAASTSSLGCYALCGQLLRLPSPPPHACSRGLSLEGLGSVLAGLLGSPMGTASSFPNVGTVGLLQAGPRRVAHLVGLFCMALGLSPRLAQLLTTIPLPVLGGVLGVTQAMVLSTGFSSFHLADIDSGRNVFIVGFSIFMALLLPRWFREASVLLKTGWSPLDVLLRSLLTEPIFLAGLLGFLLENTIPGTRLERGLGQGLPPPFTAREAPMPQKSREKADQEYELPFSIQNLCPCIPQPLRCLCPLPQDSGNEERGPSEPGETADLLPDFGDQCPQPSRGQSQL", "length": 617, "header": "tr|A0AAA9TTJ2-1|A0AAA9TTJ2_BOVIN Isoform 1 of Solute carrier family 23 member 3 OS=Bos taurus OX=9913 GN=SLC23A3 PE=3 SV=1 CANONICAL=A0AAA9TTJ2-1" }, "isoforms": [ { "isoform_ac": "A0AAA9SEJ2-1", "url": "https://www.uniprot.org/uniprotkb/A0AAA9SEJ2/entry", "sequence": { "sequence": "MSQSPPNAIQLQSVGSQGTLATLPRPPDVQNPSSDSWASLSGPPPWGLSCLLALQHILVLASLLCASHLLLLQSLPAGGLSFSPAQLLASSLFACGVSTSLQTWMGSRLPLVQAPSLQFLIPALVLTSQKLPLALRTPGNSSLVLRLCGGPGCHGLELWNTSIREVSGAVVVSGLLQAILGLLGGPGHLFPRCGPLVLAPSLVVAGLSVYREVALLCSTHWGLASLTWAPACYPHATGGQLQPLQPILTSWPSGSSRSCLPPPRHHGFGCLIQAGPRRVAHLVGLFCMALGLSPRLAQLLTTIPLPVLGGVLGVTQAMVLSTGFSSFHLADIDSGRNVFIVGFSIFMALLLPRWFREASVLLKTGWSPLDVLLRSLLTEPIFLAGLLGFLLENTIPGTRLERGLGQGLPPPFTAREAPMPQKSREKADQEYELPFSIQNLCPCIPQPLRCLCPLPQDSGNEERGPSEPGETADLLPDFGDQCPQPSRGQSQL", "length": 492, "header": "tr|A0AAA9SEJ2-1|A0AAA9TTJ2_BOVIN Computationally mapped isoform of Solute carrier family 23 member 3 OS=Bos taurus OX=9913 GN=SLC23A3 PE=3 SV=1 CANONICAL=A0AAA9TTJ2-1" }, "locus": { "chromosome": "2", "start_pos": 107120309, "end_pos": 107114328, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000097869.1", "url": "https://www.ensembl.org/id/ENSBTAT00000097869.1" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000084549.1", "url": "https://www.ensembl.org/id/ENSBTAP00000084549.1" } ] } }, { "isoform_ac": "A0AAA9TTJ2-1", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TTJ2/entry", "sequence": { "sequence": "MSQSPPNAIQLQSVGSQGTLATLPRPPDVQNPSSDSWASLSGPPPWGLSCLLALQHILVLASLLCASHLLLLQSLPAGGLSFSPAQLLASSLFACGVSTSLQTWMGSRLPLVQAPSLQFLIPALVLTSQKLPLALRTPGNCEHRARAQASLVLRLCGGPGCHGLELWNTSIREVSGAVVVSGLLQAILGLLGGPGHLFPRCGPLVLAPSLVVAGLSVYREVALLCSTHWGLASLLIVLMVVCSQHLGSCLLPPRHWRPASTSSTHTHILAFRLLSVLIPVACVWIVSALLGLSIIPGELSAPTKAPWFWLPHPAEWDWPLLTPRALAAGISMALAASTSSLGCYALCGQLLRLPSPPPHACSRGLSLEGLGSVLAGLLGSPMGTASSFPNVGTVGLLQAGPRRVAHLVGLFCMALGLSPRLAQLLTTIPLPVLGGVLGVTQAMVLSTGFSSFHLADIDSGRNVFIVGFSIFMALLLPRWFREASVLLKTGWSPLDVLLRSLLTEPIFLAGLLGFLLENTIPGTRLERGLGQGLPPPFTAREAPMPQKSREKADQEYELPFSIQNLCPCIPQPLRCLCPLPQDSGNEERGPSEPGETADLLPDFGDQCPQPSRGQSQL", "length": 617, "header": "tr|A0AAA9TTJ2-1|A0AAA9TTJ2_BOVIN Isoform 1 of Solute carrier family 23 member 3 OS=Bos taurus OX=9913 GN=SLC23A3 PE=3 SV=1 CANONICAL=A0AAA9TTJ2-1" }, "locus": { "chromosome": "2", "start_pos": 107120309, "end_pos": 107114328, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000087756.1", "url": "https://www.ensembl.org/id/ENSBTAT00000087756.1" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000100678.1", "url": "https://www.ensembl.org/id/ENSBTAP00000100678.1" } ] } }, { "isoform_ac": "E1BEZ1-1", "url": "https://www.uniprot.org/uniprotkb/E1BEZ1/entry", "sequence": { "sequence": "MSQSPPNAIQLQSVGSQGTLATLPRPPDVQNPSSDSWASLSGPPPWGLSCLLALQHILVLASLLCASHLLLLQSLPAGGLSFSPAQLLASSLFACGVSTSLQTWMGSRLPLVQAPSLQFLIPALVLTSQKLPLALRTPGNCEHRARAQASLVLRLCGGPGCHGLELWNTSIREVSGAVVVSGLLQAILGLLGGPGHLFPRCGPLVLAPSLVVAGLSVYREVALLCSTHWGLASLLIVLMVVCSQHLGSCLLPPRHWRPASTSSTHTHILAFRLLSVLIPVACVWIVSALLGLSIIPGELSAPTKAPWFWLPHPAEWDWPLLTPRALAAGISMALAASTSSLGCYALCGQLLRLPSPPPHACSRGLSLEGLGSVLAGLLGSPMGTASSFPNVGTVGLLQAGPRRVAHLVGLFCMALGLSPRLAQLLTTIPLPVLGGVLGVTQAMVLSTGFSSFHLADIDSGRNVFIVGFSIFMALLLPRWFREASVLLKTGWSPLDVLLRSLLTEPIFLAGLLGFLLENTIPGTRLERGLGQGLPPPFTAREAPMPQKSREKADQEYELPFSIQNLCPCIPQPLRCLCPLPQDSGNEERGPSEPGETADLLPDFGDQCPQPSRGQSQ", "length": 616, "header": "tr|E1BEZ1-1|A0AAA9TTJ2_BOVIN Computationally mapped isoform of Solute carrier family 23 member 3 OS=Bos taurus OX=9913 GN=SLC23A3 PE=3 SV=3 CANONICAL=A0AAA9TTJ2-1" }, "locus": { "chromosome": "2", "start_pos": 107120309, "end_pos": 107114328, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000016751.7", "url": "https://www.ensembl.org/id/ENSBTAT00000016751.7" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000016751.6", "url": "https://www.ensembl.org/id/ENSBTAP00000016751.6" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [ { "id": "bta:523081", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?bta:523081", "resource": "KEGG Pathway" } ], "orthologs": [ { "uniprot_canonical_ac": "A0A8V0ZK27-1", "protein_name": "Solute carrier family 23 member 3", "gene_name": "SLC23A3", "tax_id": 9031, "organism": "Gallus gallus", "sequence": { "sequence": "MRGGSSMNGGRHPVTGAGSPALTSCSWPKMCSWTLSCCLALQHLAVQASLLCIFHLLLLPALSEEQLHIPAASVLLARSLFACGISTLLQTTLGSRLPLVQIPSFEYLVPALVLSSHLSLGVSEDGNGMAVATVCPEPHCTIMESRATSLQEVSGAVLISGLVQLVLGALGVCGWAVQRCGPMVLAPSLSIIGLSAYKEAAFFCSANWGVALLLMLLTITFSQHLGSCRLPFCAWPYAPGVSVEPSVPTLRTLSVLLPFAIVCIVCSIVHHFHVSWDLPDLATAQLSWVNSTLRAPWLQLPYAGEWPLLTPRALAVGIAMAFGCSINSVGCYVLCGRLLRAPQPPSHTCNRGLCIEGLGSLLAGLLGSAGGTAASIANACAGGLTQDGSRLSVQLNALACVMLGMSPRLVGLLAHIPLAVHGGVLCVTYAVAVGTGISYFQYADIDSGRNIFIVGFTMFMALLVPRWLSVAPARLVTGWVPLDLLFLSLLVMPVFLTGFLSFFLENTVSGTLEERGLLADRVQRKPGTSSGQPWREESKASPVYGLPTRLRRLLPSSCKAFPCCFLCPGSEDEKEEEEDGGRVAEEGMAAAGEGTHLLLKPGTGDMQADRQPSQAEMLAWHTGA", "length": 624 }, "evidence": [ { "id": "A0AAA9TTJ2", "url": "https://omabrowser.org/oma/group/A0AAA9TTJ2/", "database": "OMA" } ], "glygen_name": "Chicken", "common_name": "Chicken" }, { "uniprot_canonical_ac": "D3ZG28-1", "protein_name": "Solute carrier family 23, member 3", "gene_name": "Slc23a3", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MSRSPPHPIPLLSVGSQDTPAPRPPLLPPLQDPSSRSWASWCGPSTWGLSCLLALQHFLVLTSLLWASHLLLLHSLPPGGLSYPPAQLLASSFFSCGMSTVLQTWMGSRLPLIQAPSLEFLIPALVLTNQKLPLMTKTPGNASLSLRLCSLTRSCHGPELWNTSLREVSGAVVMSGLLQGTMGLLGVPGRVFPYCGPLVLAPSLVVAGLSAHKEVAQFCSAHWGLALLLILLMVVCSQHLGSCQVPLCSWRPASTSSTHIYIPIFRLLSVLAPVACVWLISACLGLSVIPLQLSEPSDAPWFWLPHPGEWEWPLLTPKALAAGISMALAASTSSLGCYALCGQLLHLSPPPPHACSRGLSLEGLGSVLAGLLGSPLGTASSFPNVGTVSLFQTGSRRVAHLVGLFCMGLGLSPRLAQLFTNIPLPVLGGVLGVTQAVVLSAGFSSFHLADIDSGRNVFIVGFSIFMALLLPRWLREAPILLNTGWSPMDMFLRSLLAEPIFLAGLLGFLLENTISGTRIERGLGQALPTSFTAQETQMLQKSRKKAAQEYGLPLSIKNLCSCIPQPLRCLCPMPEDSGDEGGSSKTGETADLLPNSGESSSPDGREGFRS", "length": 610 }, "evidence": [ { "id": "A0AAA9TTJ2", "url": "https://omabrowser.org/oma/group/A0AAA9TTJ2/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "Q60850-1", "protein_name": "Solute carrier family 23 member 3", "gene_name": "Slc23a3", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MSRSPLHPIPLLSEGYQDTPAPLPPLLPPLQNPSSRSWASRVFGPSTWGLSCLLALQHFLVLASLLWASHLLLLHGLPPGGLSYPPAQLLASSFFSCGLSTVLQTWMGSRLPLIQAPSLEFLIPALVLTNQKLPLTTKTPGNASLSLPLCSLTRSCHGLELWNTSLREVSGAVVVSGLLQGTIGLLGVPGRVFPYCGPLVLAPSLVVAGLSAHKEVAQFCSAHWGLALLLILLMVVCSQHLGSCQIPLCSWRPSSTSTHICIPVFRLLSVLAPVACVWFISAFVGTSVIPLQLSEPSDAPWFWLPHPGEWEWPLLTPRALAAGISMALAASTSSLGCYALCGQLLRLSPPPPHACSRGLSLEGLGSVLAGLLGSPLGTASSFPNVGTVSLFQTGSRRVAHLVGLFCMGLGLSPRLAQLFTSIPLPVLGGVLGVTQAVVLSAGFSSFHLADIDSGRNVFIVGFSIFMALLLPRWLREAPVLLNTGWSPLDMFLRSLLAEPIFLAGLLGFLLENTISGTRAERGLGQRLPTSFTAQEIQMLQQSRRKAAQEYGLPLPIKNLCSCIPQPLHCLCPMPEDSGDEGGSSKTGERADLLPNSGESYSTASREGVRSQ", "length": 611 }, "evidence": [ { "id": "A0AAA9TTJ2", "url": "https://omabrowser.org/oma/group/A0AAA9TTJ2/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q6PIS1-1", "protein_name": "Solute carrier family 23 member 3", "gene_name": "SLC23A3", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MSRSPLNPSQLRSVGSQDALAPLPPPAPQNPSTHSWDPLCGSLPWGLSCLLALQHVLVMASLLCVSHLLLLCSLSPGGLSYSPSQLLASSFFSCGMSTILQTWMGSRLPLVQAPSLEFLIPALVLTSQKLPRAIQTPGNSSLMLHLCRGPSCHGLGHWNTSLQEVSGAVVVSGLLQGMMGLLGSPGHVFPHCGPLVLAPSLVVAGLSAHREVAQFCFTHWGLALLVILLMVVCSQHLGSCQFHVCPWRRASTSSTHTPLPVFRLLSVLIPVACVWIVSAFVGFSVIPQELSAPTKAPWIWLPHPGEWNWPLLTPRALAAGISMALAASTSSLGCYALCGRLLHLPPPPPHACSRGLSLEGLGSVLAGLLGSPMGTASSFPNVGKVGLIQAGSQQVAHLVGLLCVGLGLSPRLAQLLTTIPLPVVGGVLGVTQAVVLSAGFSSFYLADIDSGRNIFIVGFSIFMALLLPRWFREAPVLFSTGWSPLDVLLHSLLTQPIFLAGLSGFLLENTIPGTQLERGLGQGLPSPFTAQEARMPQKPREKAAQVYRLPFPIQNLCPCIPQPLHCLCPLPEDPGDEEGGSSEPEEMADLLPGSGEPCPESSREGFRSQK", "length": 610 }, "evidence": [ { "id": "A0AAA9TTJ2", "url": "https://omabrowser.org/oma/group/A0AAA9TTJ2/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" } ], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 1, "go_terms": [ { "name": "membrane", "id": "GO:0016020", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016020", "evidence": [ { "database": "UniProtKB", "id": "A0AAA9TTJ2", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TTJ2" } ], "pmid": "" } ] }, { "name": "Molecular Function", "total": 1, "go_terms": [ { "name": "transmembrane transporter activity", "id": "GO:0022857", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0022857", "evidence": [ { "database": "UniProtKB", "id": "A0AAA9TTJ2", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TTJ2" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 1, "go_terms": [ { "name": "hypoxanthine transport", "id": "GO:0035344", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0035344", "evidence": [ { "database": "UniProtKB", "id": "A0AAA9TTJ2", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TTJ2" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 168, "end_pos": 170, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" }, { "name": "homologset.oma", "label": "OMA Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 168, "end_pos": 170 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ], "tool_support": { "graph_view": "yes" } }, { "uniprot_canonical_ac": "A0AAA9TW55-1", "uniprot_ac": "A0AAA9TW55", "uniprot_id": "A0AAA9TW55_BOVIN", "mass": { "chemical_mass": 65254.0, "monoisotopic_mass": 65254.0 }, "refseq": {}, "gene_names": [ { "name": "SLC23A1", "type": "recommended", "evidence": [ { "id": "A0AAA9TW55", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TW55" } ] } ], "protein_names": [ { "name": "Solute carrier family 23 member 1", "type": "synonym", "evidence": [ { "id": "A0AAA9TW55", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TW55/entry#names_and_taxonomy" } ] } ], "function": [], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Bos taurus", "taxid": 9913, "evidence": [ { "database": "UniProtKB", "id": "A0AAA9TW55", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TW55" } ], "common_name": "Bovine", "glygen_name": "Bovine", "reference_species": "Bos taurus [9913]" } ], "gene": [ { "name": "SLC23A1", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TW55", "locus": { "chromosome": "7", "start_pos": 50647652, "end_pos": 50661422, "strand": "+", "evidence": [ { "database": "Ensembl Gene", "id": "ENSBTAG00000010798", "url": "https://www.ensembl.org/id/ENSBTAG00000010798" } ] } } ], "crossref": [ { "id": "A0AAA9TW55", "url": "https://alphafold.ebi.ac.uk/entry/A0AAA9TW55", "database": "AlphaFoldDB", "categories": [] }, { "id": "ENSBTAG00000010798", "url": "https://bgee.org/?page=gene&gene_id=ENSBTAG00000010798", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "505492", "url": "https://www.ncbi.nlm.nih.gov/gene/505492", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR006043", "url": "https://www.ebi.ac.uk/interpro/entry/IPR006043", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "bta:505492", "url": "https://www.genome.jp/dbget-bin/www_bget?bta:505492", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "E1BI45", "url": "https://www.orthodb.org/?gene=E1BI45", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR11119", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR11119", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00860", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00860", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "R-BTA-196836", "url": "https://www.reactome.org/PathwayBrowser/#R-BTA-196836", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "A0AAA9SEP5", "url": "https://www.uniprot.org/uniprotkb/A0AAA9SEP5", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0AAA9SEP5-1", "url": "https://www.uniprot.org/uniprotkb/A0AAA9SEP5-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0AAA9TI55", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TI55", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0AAA9TI55-1", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TI55-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0AAA9TVF2", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TVF2", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0AAA9TVF2-1", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TVF2-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0AAA9TW55", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TW55", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0AAA9TW55-1", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TW55-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "E1BI45", "url": "https://www.uniprot.org/uniprotkb/E1BI45", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "E1BI45-1", "url": "https://www.uniprot.org/uniprotkb/E1BI45-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MRAREDAEGQTQHESTRDPPVSLSTEPKFDMLYKIEDVPPWYLCILLGFQHYLTCFSGTIAVPFLLAEALCVGRDQYMVSQLIGTIFTCVGITTLIQTTLGIRLPLFQASAFAFLVPAKAILALEKWKCPPEEEIYGNWSLPLNTSHIWHPRIREVGLHVQGAIMVSSMVEVVIGLMGLPGALLSYIGPLTVTPTVSLIGLSVFQAAGDRAGSHWGISACSILLIVLFSQYLRNLTFLLPVYRWGKGLTLFRIQIFKMFPIVLAIMTVWLLCYVLTLTDMLPSDPTAYGFQARTDARGDIMAIAPWIRIPYPCQWGLPTVTAAAVLGMFSATLAGIIESIGDYYACARLAGAPPPPVHAINRGIFTEGICCIIAGLLGTGNGSTSSSPNIGVLGITKVGSRRVVQYGAGIMLILGTIGKFTALFASLPDPILGGMFCTLFGMITAVGLSNLQFVDMNSSRNLFVLGFSMFFGLTLPNYLDSNPDVINTGVPEVDQILTVLLTTEMFVGGCLAFILDNTVPGSPEERGLIQWKAGAHADSEMSSSLKSYDFPIGMSMVKRIAFLKYIPICPVFKGFPSRSKNQLPVPEDIPENTETVYTKV", "length": 600, "header": "tr|A0AAA9TW55-1|A0AAA9TW55_BOVIN Isoform 1 of Solute carrier family 23 member 1 OS=Bos taurus OX=9913 GN=SLC23A1 PE=3 SV=1 CANONICAL=A0AAA9TW55-1" }, "isoforms": [ { "isoform_ac": "A0AAA9SEP5-1", "url": "https://www.uniprot.org/uniprotkb/A0AAA9SEP5/entry", "sequence": { "sequence": "MRAREDAEGQTQHYLTCFSGTIAVPFLLAEALCVGRDQYMVSQLIGTIFTCVGITTLIQTTLGIRLPLFQASAFAFLVPAKAILALEKWKCPPEEEIYGNWSLPLNTSHIWHPRIREVQGAIMVSSMVEVVIGLMGLPGALLSYIGPLTVTPTVSLIGLSVFQAAGDRAGSHWGISACSILLIVLFSQYLRNLTFLLPVYRWGKGLTLFRIQIFKMFPIVLAIMTVWLLCYVLTLTDMLPSDPTAYGFQARTDARGDIMAIAPWIRIPYPCQWGLPTVTAAAVLGMFSATLAGIIESIGDYYACARLAGAPPPPVHAINRGIFTEGICCIIAGLLGTGNGSTSSSPNIGVLGITKVGSRRVVQYGAGIMLILGTIGKFTALFASLPDPILGGMFCTLFGMITAVGLSNLQFVDMNSSRNLFVLGFSMFFGLTLPNYLDSNPDVINTGVPEVDQILTVLLTTEMFVGGCLAFILDNTVPGSPEERGLIQWKAGAHADSEMSSSLKSYDFPIGMSMVKRIAFLKYIPICPVFKGFPSRSKNQLPVPEDIPENTETVYTKV", "length": 558, "header": "tr|A0AAA9SEP5-1|A0AAA9TW55_BOVIN Computationally mapped isoform of Solute carrier family 23 member 1 OS=Bos taurus OX=9913 GN=SLC23A1 PE=3 SV=1 CANONICAL=A0AAA9TW55-1" }, "locus": { "chromosome": "7", "start_pos": 50658869, "end_pos": 50647674, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000097528.1", "url": "https://www.ensembl.org/id/ENSBTAT00000097528.1" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000084603.1", "url": "https://www.ensembl.org/id/ENSBTAP00000084603.1" } ] } }, { "isoform_ac": "A0AAA9TI55-1", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TI55/entry", "sequence": { "sequence": "MDFSGCQRSLLSYSICCPQHESLGSAGTSTRDPPVSLSTEPKFDMLYKIEDVPPWYLCILLGFQHYLTCFSGTIAVPFLLAEALCVGRDQYMVSQLIGTIFTCVGITTLIQTTLGIRLPLFQASAFAFLVPAKAILALEKWKCPPEEEIYGNWSLPLNTSHIWHPRIREVQGAIMVSSMVEVVIGLMGLPGALLSYIGPLTVTPTVSLIGLSVFQAAGDRAGSHWGISACSILLIVLFSQYLRNLTFLLPVYRWGKGLTLFRIQIFKMFPIVLAIMTVWLLCYVLTLTDMLPSDPTAYGFQARTDARGDIMAIAPWIRIPYPCQWGLPTVTAAAVLGMFSATLAGIIESIGDYYACARLAGAPPPPVHAINRGIFTEGICCIIAGLLGTGNGSTSSSPNIGVLGITKVGSRRVVQYGAGIMLILGTIGKFTALFASLPDPILGGMFCTLFGVPEVDQILTVLLTTEMFVGGCLAFILDNTVPGSPEERGLIQWKAGAHADSEMSSSLKSYDFPIGMSMVKRIAFLKYIPICPVFKGFPSRSKNQLPVPEDIPENTETVYTKV", "length": 562, "header": "tr|A0AAA9TI55-1|A0AAA9TW55_BOVIN Computationally mapped isoform of Solute carrier family 23 member 1 OS=Bos taurus OX=9913 GN=SLC23A1 PE=3 SV=1 CANONICAL=A0AAA9TW55-1" }, "locus": { "chromosome": "7", "start_pos": 50658260, "end_pos": 50647674, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000105466.1", "url": "https://www.ensembl.org/id/ENSBTAT00000105466.1" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000097967.1", "url": "https://www.ensembl.org/id/ENSBTAP00000097967.1" } ] } }, { "isoform_ac": "A0AAA9TVF2-1", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TVF2/entry", "sequence": { "sequence": "MKLLPSWTAVLPGSPRGRAWPWAQRTRRTAHTCAPKMRAREDAEGQTQHESLGSAGTSTRDPPVSLSTEPKFDMLYKIEDVPPWYLCILLGFQHYLTCFSGTIAVPFLLAEALCVGRDQYMVSQLIGTIFTCVGITTLIQTTLGIRLPLFQASAFAFLVPAKAILALEKWKCPPEEEIYGNWSLPLNTSHIWHPRIREVQGAIMVSSMVEVVIGLMGLPGALLSYIGPLTVTPTVSLIGLSVFQAAGDRAGSHWGISACSILLIVLFSQYLRNLTFLLPVYRWGKGLTLFRIQIFKMFPIVLAIMTVWLLCYVLTLTDMLPSDPTAYGFQARTDARGDIMAIAPWIRIPYPCQWGLPTVTAAAVLGMFSATLAGIIESIGDYYACARLAGAPPPPVHAINRGIFTEGICCIIAGLLGTGNGSTSSSPNIGVLGITKVGSRRVVQYGAGIMLILGTIGKFTALFASLPDPILGGMFCTLFGMITAVGLSNLQFVDMNSSRNLFVLGFSMFFGLTLPNYLDSNPDVINTGVPEVDQILTVLLTTEMFVGGCLAFILDNTVPGSPEERGLIQWKAGAHADSEMSSSLKSYDFPIGMSMVKRIAFLKYIPICPVFKGFPSRSKNQLPVPEDIPENTETVYTKV", "length": 639, "header": "tr|A0AAA9TVF2-1|A0AAA9TVF2_BOVIN Computationally mapped isoform of Solute carrier family 23 member 1 OS=Bos taurus OX=9913 GN=SLC23A1 PE=3 SV=1 CANONICAL=A0AAA9TW55-1" }, "locus": { "chromosome": "7", "start_pos": 50660051, "end_pos": 50647674, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000114937.1", "url": "https://www.ensembl.org/id/ENSBTAT00000114937.1" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000101115.1", "url": "https://www.ensembl.org/id/ENSBTAP00000101115.1" } ] } }, { "isoform_ac": "A0AAA9TW55-1", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TW55/entry", "sequence": { "sequence": "MRAREDAEGQTQHESTRDPPVSLSTEPKFDMLYKIEDVPPWYLCILLGFQHYLTCFSGTIAVPFLLAEALCVGRDQYMVSQLIGTIFTCVGITTLIQTTLGIRLPLFQASAFAFLVPAKAILALEKWKCPPEEEIYGNWSLPLNTSHIWHPRIREVGLHVQGAIMVSSMVEVVIGLMGLPGALLSYIGPLTVTPTVSLIGLSVFQAAGDRAGSHWGISACSILLIVLFSQYLRNLTFLLPVYRWGKGLTLFRIQIFKMFPIVLAIMTVWLLCYVLTLTDMLPSDPTAYGFQARTDARGDIMAIAPWIRIPYPCQWGLPTVTAAAVLGMFSATLAGIIESIGDYYACARLAGAPPPPVHAINRGIFTEGICCIIAGLLGTGNGSTSSSPNIGVLGITKVGSRRVVQYGAGIMLILGTIGKFTALFASLPDPILGGMFCTLFGMITAVGLSNLQFVDMNSSRNLFVLGFSMFFGLTLPNYLDSNPDVINTGVPEVDQILTVLLTTEMFVGGCLAFILDNTVPGSPEERGLIQWKAGAHADSEMSSSLKSYDFPIGMSMVKRIAFLKYIPICPVFKGFPSRSKNQLPVPEDIPENTETVYTKV", "length": 600, "header": "tr|A0AAA9TW55-1|A0AAA9TW55_BOVIN Isoform 1 of Solute carrier family 23 member 1 OS=Bos taurus OX=9913 GN=SLC23A1 PE=3 SV=1 CANONICAL=A0AAA9TW55-1" }, "locus": { "chromosome": "7", "start_pos": 50658869, "end_pos": 50647674, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000127383.1", "url": "https://www.ensembl.org/id/ENSBTAT00000127383.1" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000101670.1", "url": "https://www.ensembl.org/id/ENSBTAP00000101670.1" } ] } }, { "isoform_ac": "E1BI45-1", "url": "https://www.uniprot.org/uniprotkb/E1BI45/entry", "sequence": { "sequence": "MLKLVVSFVSLGGGQNRHCNTLLTPWLRQQKDSGRVLGTAHTCAPKMRAREDAEGQTQHESLGSAGTSTRDPPVSLSTEPKFDMLYKIEDVPPWYLCILLGFQHYLTCFSGTIAVPFLLAEALCVGRDQYMVSQLIGTIFTCVGITTLIQTTLGIRLPLFQASAFAFLVPAKAILALEKWKCPPEEEIYGNWSLPLNTSHIWHPRIREVQGAIMVSSMVEVVIGLMGLPGALLSYIGPLTVTPTVSLIGLSVFQAAGDRAGSHWGISACSILLIVLFSQYLRNLTFLLPVYRWGKGLTLFRIQIFKMFPIVLAIMTVWLLCYVLTLTDMLPSDPTAYGFQARTDARGDIMAIAPWIRIPYPCQWGLPTVTAAAVLGMFSATLAGIIESIGDYYACARLAGAPPPPVHAINRGIFTEGICCIIAGLLGTGNGSTSSSPNIGVLGITKVGSRRVVQYGAGIMLILGTIGKFTALFASLPDPILGGMFCTLFGMITAVGLSNLQFVDMNSSRNLFVLGFSMFFGLTLPNYLDSNPDVINTGVPEVDQILTVLLTTEMFVGGCLAFILDNTVPGSPEERGLIQWKAGAHADRFPSRSKNQLPVPEDIPENTETVYTKV", "length": 614, "header": "tr|E1BI45-1|E1BI45_BOVIN Computationally mapped isoform of Solute carrier family 23 member 1 OS=Bos taurus OX=9913 GN=SLC23A1 PE=3 SV=4 CANONICAL=A0AAA9TW55-1" }, "locus": { "chromosome": "7", "start_pos": 50660822, "end_pos": 50647674, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000010823.7", "url": "https://www.ensembl.org/id/ENSBTAT00000010823.7" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000010823.7", "url": "https://www.ensembl.org/id/ENSBTAP00000010823.7" } ] } } ], "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "other", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 195, "start_aa": "Thr", "end_pos": 195, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr195", "evidence": [ { "id": "", "database": "GlyGen", "url": "https://data.glygen.org/" } ], "filter_code": "000000000000000010000.00000000001000.0.01000" } ], "phosphorylation": [], "glycation": [], "keywords": [ "glycoprotein", "glycoprotein_predicted" ], "publication": [], "pathway": [ { "id": "bta:505492", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?bta:505492", "resource": "KEGG Pathway" }, { "id": "R-BTA-196836", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-BTA-196836", "resource": "Reactome", "description": "Vitamin C (ascorbate) metabolism" } ], "orthologs": [], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 6, "go_terms": [ { "name": "membrane", "id": "GO:0016020", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016020", "evidence": [ { "database": "UniProtKB", "id": "A0AAA9TW55", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TW55" } ], "pmid": "" }, { "name": "cytoplasm", "id": "GO:0005737", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005737", "evidence": [ { "database": "UniProtKB", "id": "A0AAA9TW55", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TW55" } ], "pmid": "" }, { "name": "apical plasma membrane", "id": "GO:0016324", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016324", "evidence": [ { "database": "UniProtKB", "id": "A0AAA9TW55", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TW55" } ], "pmid": "" }, { "name": "basal plasma membrane", "id": "GO:0009925", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0009925", "evidence": [ { "database": "UniProtKB", "id": "A0AAA9TW55", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TW55" } ], "pmid": "" }, { "name": "plasma membrane", "id": "GO:0005886", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005886", "evidence": [ { "database": "UniProtKB", "id": "A0AAA9TW55", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TW55" } ], "pmid": "" }, { "name": "intracellular organelle", "id": "GO:0043229", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0043229", "evidence": [ { "database": "UniProtKB", "id": "A0AAA9TW55", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TW55" } ], "pmid": "" } ] }, { "name": "Molecular Function", "total": 6, "go_terms": [ { "name": "transmembrane transporter activity", "id": "GO:0022857", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0022857", "evidence": [ { "database": "UniProtKB", "id": "A0AAA9TW55", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TW55" } ], "pmid": "" }, { "name": "L-ascorbate:sodium symporter activity", "id": "GO:0008520", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008520", "evidence": [ { "database": "UniProtKB", "id": "A0AAA9TW55", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TW55" } ], "pmid": "" }, { "name": "L-ascorbic acid transmembrane transporter activity", "id": "GO:0015229", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0015229", "evidence": [ { "database": "UniProtKB", "id": "A0AAA9TW55", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TW55" } ], "pmid": "" }, { "name": "dehydroascorbic acid transmembrane transporter activity", "id": "GO:0033300", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0033300", "evidence": [ { "database": "UniProtKB", "id": "A0AAA9TW55", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TW55" } ], "pmid": "" }, { "name": "urate transmembrane transporter activity", "id": "GO:0015143", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0015143", "evidence": [ { "database": "UniProtKB", "id": "A0AAA9TW55", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TW55" } ], "pmid": "" }, { "name": "sodium ion transmembrane transporter activity", "id": "GO:0015081", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0015081", "evidence": [ { "database": "UniProtKB", "id": "A0AAA9TW55", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TW55" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 6, "go_terms": [ { "name": "lung development", "id": "GO:0030324", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030324", "evidence": [ { "database": "UniProtKB", "id": "A0AAA9TW55", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TW55" } ], "pmid": "" }, { "name": "brain development", "id": "GO:0007420", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007420", "evidence": [ { "database": "UniProtKB", "id": "A0AAA9TW55", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TW55" } ], "pmid": "" }, { "name": "response to toxic substance", "id": "GO:0009636", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0009636", "evidence": [ { "database": "UniProtKB", "id": "A0AAA9TW55", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TW55" } ], "pmid": "" }, { "name": "L-ascorbic acid transmembrane transport", "id": "GO:0015882", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0015882", "evidence": [ { "database": "UniProtKB", "id": "A0AAA9TW55", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TW55" } ], "pmid": "" }, { "name": "dehydroascorbic acid transport", "id": "GO:0070837", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0070837", "evidence": [ { "database": "UniProtKB", "id": "A0AAA9TW55", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TW55" } ], "pmid": "" }, { "name": "sodium ion transport", "id": "GO:0006814", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006814", "evidence": [ { "database": "UniProtKB", "id": "A0AAA9TW55", "url": 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"https://www.uniprot.org/uniprotkb/A0AAA9T7D0", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0AAA9T7D0-1", "url": "https://www.uniprot.org/uniprotkb/A0AAA9T7D0-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0AAA9TT61", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TT61", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0AAA9TT61-1", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TT61-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "F1N6R8", "url": "https://www.uniprot.org/uniprotkb/F1N6R8", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "F1N6R8-1", "url": "https://www.uniprot.org/uniprotkb/F1N6R8-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "G3MZ56", "url": "https://www.uniprot.org/uniprotkb/G3MZ56", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "G3MZ56-1", "url": "https://www.uniprot.org/uniprotkb/G3MZ56-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MNEEMATDSPRRPSRCTGGVVVRPQAVTEQSYMESVVTFLQDVVPQAYSGTPLTEEKEKIVWVRFENADLNDTSRNLEFHEIHSTGNEPPLLIMIGYSDGMQVWSIPISGEAQELFSVRHGPIRAARILPAPQFGAQKCDNFAEKRPLLGVCKSTGSSGTSPPYCCVDLYSLRTGEMVKSIQFKTPIYDLHCNKRILVVVLQEKIAAFDSCTFTKKFFVTSCYPCPGPNMNPVALGSRWLAYAENKLIRCHQSRGGACGDNIQSYTATVISAAKTLKTGLTMVGKVVTQLTGTLPSGVTEDDVAIHSNSRRSPLVPGIITVIDTETVGEGQVLVSEDSDSDGIVAHFPAHEKPVCCMAFNTSGMLLVTTDTLGHDFHVFQILTHPWSSSQSAVHHLYTLHRGETEAKVQDICFSHDCRWVVVSTLRGTSHVFPINPYGGQPCVRTHMSPRVVNRMSRFQKSAGLEEIEQELTSKQGGRCSPVPGLSSSPSGSPLHGKLNSQDSYNNFANNNPGNPRLSPLPSLMVLMPLAQIKQPMTLGTITKRTGPYLFGAGCFSIKAPCKVKPPPQISPSKSMGGEFCVAATFGTSRSWFANNAGLKREKDQSKQVVVESLYIISCYGTLVEHVMEPRPLSTAPKISDDTPLEMMTSPRASWTLVRTPQWNELQPPFNANHPLLLAADAVQYYQFLLAGLAPPGSPGPITRHGSYDSLASDHSGQEDEEWLSQVEIVTHTGPHRRLWMGPQFQFKTIHPSGQTTVISSSSSVLQSHGPSDTPQPLSDFDTDDLDLNSLRIQPVRSDPVSMPGSSRPVSDRRGISTVIDAASGTFDRSVTLLEVCGSWPEGFGLRHMASMEHTEEGLRERLADAMAESPSRDVVGPGTDTAFEVAVKATTPERHMVVKCVELQREGSIETLSNSSGSTSGSIPRNFDGYRSPLPTNESQPLSLFPTSFP", "length": 950, "header": "tr|A0AAA9TT61-1|A0AAA9TT61_BOVIN Isoform 1 of BCAS3 microtubule associated cell migration factor OS=Bos taurus OX=9913 GN=BCAS3 PE=3 SV=2 CANONICAL=A0AAA9TT61-1" }, "isoforms": [ { "isoform_ac": "A0AAA9SH44-1", "url": "https://www.uniprot.org/uniprotkb/A0AAA9SH44/entry", "sequence": { "sequence": "MNEEMATDSPRRPSRCTGGVVVRPQAVTEQSYMESVVTFLQDVVPQKSNVGEEL", "length": 54, "header": "tr|A0AAA9SH44-1|A0AAA9TT61_BOVIN Computationally mapped isoform of BCAS3 microtubule associated cell migration factor OS=Bos taurus OX=9913 GN=BCAS3 PE=3 SV=2 CANONICAL=A0AAA9TT61-1" }, "locus": { "chromosome": "19", "start_pos": 12284418, "end_pos": 12273711, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000089759.1", "url": "https://www.ensembl.org/id/ENSBTAT00000089759.1" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000085529.1", "url": "https://www.ensembl.org/id/ENSBTAP00000085529.1" } ] } }, { "isoform_ac": "A0AAA9T1R9-1", "url": "https://www.uniprot.org/uniprotkb/A0AAA9T1R9/entry", "sequence": { "sequence": "MATDSPRRPSRCTGGVVVRPQAVTEQSYMESVVTFLQDVVPQAYSGTPLTEEKEKIVWVRFENADLNDTSRNLEFHEIHSTGNEPPLLIMIGYSDGMQVWSIPISGEAQELFSVRHGPIRAARILPAPQFGAQKCDNFAEKRPLLGVCKSTGSSGTSPPYCCVDLYSLRTGEMVKSIQFKTPIYDLHCNKRILVVVLQEKIAAFDSCTFTKKFFVTSCYPCPGPNMNPVALGSRWLAYAENKLIRCHQSRGGACGDNIQSYTATVISAAKTLKTGLTMVGKVVTQLTGTLPSGVTEDDVAIHSNSRRSPLVPGIITVIDTETVGEGQVLVSEDSDSDGIVAHFPAHEKPVCCMAFNTSGMLLVTTDTLGHDFHVFQILTHPWSSSQSAVHHLYTLHRGETEAKVQDICFSHDCRWVVVSTLRGTSHVFPINPYGGQPCVRTHMSPRVVNRMSRFQKSAGLEEIEQELTSKQGGRCSPVPGLSSSPSGSPLHGKLNSQDSYNNFANNNPGNPRLSPLPSLMVLMPLAQIKQPMTLGTITKRTGKVKPPPQISPSKSMGGEFCVAATFGTSRSWFANNAGLKREKDQSKQVVVESLYIISCYGTLVEHVMEPRPLSTAPKISDDTPLEMMTSPRASWTLVRTPQWNELQPPFNANHPLLLAADAVQYYQFLLAGLAPPGSPGPITRHGSYDSLASDHSGQEDEEWLSQVEIVTHTGPHRRLWMGPQFQFKTIHPSGQTTVISSSSSVLQSHGPSDTPQPLSDFDTDDLDLNSLRIQPVRSDPVSMPGSSRPVSDRRGISTVIDAASGQSFKELCNLPTSFPLSWNSRVKLDAGWTSVAEFESFQRPQSDNFSRLLSHRTILRDALHRLT", "length": 867, "header": "tr|A0AAA9T1R9-1|A0AAA9TT61_BOVIN Computationally mapped isoform of BCAS3 microtubule associated cell migration factor OS=Bos taurus OX=9913 GN=BCAS3 PE=3 SV=1 CANONICAL=A0AAA9TT61-1" }, "locus": { "chromosome": "19", "start_pos": 12284406, "end_pos": 11821925, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000107401.1", "url": "https://www.ensembl.org/id/ENSBTAT00000107401.1" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000090352.1", "url": "https://www.ensembl.org/id/ENSBTAP00000090352.1" } ] } }, { "isoform_ac": "A0AAA9T604-1", "url": "https://www.uniprot.org/uniprotkb/A0AAA9T604/entry", "sequence": { "sequence": "MNEEMATDSPRRPSRCTGGVVVRPQAVTEQSYMESVVTFLQDVVPQAYSGTPLTEEKEKIVWVRFENADLNDTSRNLEFHEIHSTGNEPPLLIMIGYSDGMQVWSIPISGEAQELFSVRHGPIRAARILPAPQFGAQKCDNFAEKRPLLGVCKSTGSSGTSPPYCCVDLYSLRTGEMVKSIQFKTPIYDLHCNKRILVVVLQEKIAAFDSCTFTKKFFVTSCYPCPGPNMNPVALGSRWLAYAENKLIRCHQSRGGACGDNIQSYTATVISAAKTLKTGLTMVGKVVTQLTGTLPSGVTEDDVAIHSNSRRSPLVPGIITVIDTETVGEGQVLVSEDSDSDGIVAHFPAHEKPVCCMAFNTSGMLLVTTDTLGHDFHVFQILTHPWSSSQSAVHHLYTLHRGETEAKVQDICFSHDCRWVVVSTLRGTSHVFPINPYGGQPCVRTHMSPRVVNRMSRFQKSAGLEEIEQELTSKQGGRCSPVPGLSSSPSGSPLHGKLNSQDSYNNFANNNPGNPRLSPLPSLMVLMPLAQIKQPMTLGTITKRTGKVKPPPQISPSKSMGGEFCVAATFGTSRSWFANNAGLKREKDQSKQVVVESLYIISCYGTLVEHVMEPRPLSTAPKISDDTPLEMMTSPRASWTLVRTPQWNELQPPFNANHPLLLAADAVQYYQFLLAGLAPPGSPGPITRHGSYDSLASDHSGQEDEEWLSQVEIVTHTGPHRRLWMGPQFQFKTIHPSGQTTVISSSSSVLQSHGPSDTPQPLSDFDTDDLDLNSLRIQPVRSDPVSMPGSSRPVSDRRGISTVIDAASGTFDRSVTLLEVCGSWPEGFGLRHMASMEHTEEGLRERLADAMAESPSRDVVGPGTELQREGSIETLSNSSGSTSGSIPRNFDGYRSPLPTNESQPLSLFPTSFP", "length": 913, "header": "tr|A0AAA9T604-1|A0AAA9TT61_BOVIN Computationally mapped isoform of BCAS3 microtubule associated cell migration factor OS=Bos taurus OX=9913 GN=BCAS3 PE=3 SV=2 CANONICAL=A0AAA9TT61-1" }, "locus": { "chromosome": "19", "start_pos": 12284418, "end_pos": 11700368, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000115513.1", "url": "https://www.ensembl.org/id/ENSBTAT00000115513.1" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000091197.1", "url": "https://www.ensembl.org/id/ENSBTAP00000091197.1" } ] } }, { "isoform_ac": "A0AAA9T7D0-1", "url": "https://www.uniprot.org/uniprotkb/A0AAA9T7D0/entry", "sequence": { "sequence": "MNPVSYKQEMGDTERSVSEGFLNEEMATDSPRRPSRCTGGVVVRPQAVTEQSYMESVVTFLQDVVPQAYSGTPLTEEKEKIVWVRFENADLNDTSRNLEFHEIHSTGNEPPLLIMIGYSDGMQVWSIPISGEAQELFSVRHGPIRAARILPAPQFGAQKCDNFAEKRPLLGVCKSTGSSGTSPPYCCVDLYSLRTGEMVKSIQFKTPIYDLHCNKRILVVVLQEKIAAFDSCTFTKKFFVTSCYPCPGPNMNPVALGSRWLAYAENKLIRCHQSRGGACGDNIQSYTATVISAAKTLKTGLTMVGKVVTQLTGTLPSGVTEDDVAIHSNSRRSPLVPGIITVIDTETVGEGQVLVSEDSDSDGIVAHFPAHEKPVCCMAFNTSGMLLVTTDTLGHDFHVFQILTHPWSSSQSAVHHLYTLHRGETEAKVQDICFSHDCRWVVVSTLRGTSHVFPINPYGGQPCVRTHMSPRVVNRMSRFQKSAGLEEIEQELTSKQGGRCSPVPGLSSSPSGSPLHGKLNSQDSYNNFANNNPGNPRLSPLPSLMVLMPLAQIKQPMTLGTITKRTGKVKPPPQISPSKSMGGEFCVAATFGTSRSWFANNAGLKREKDQSKQVVVESLYIISCYGTLVEHVMEPRPLSTAPKISDDTPLEMMTSPRASWTLVRTPQWNELQPPFNANHPLLLAADAVQYYQFLLAGLAPPGSPGPITRHGSYDSLASDHSGQEDEEWLSQVEIVTHTGPHRRLWMGPQFQFKTIHPSGQTTVISSSSSVLQSHGPSDTPQPLSDFDTDDLDLNSLRIQPVRSDPVSMPGSSRPVSDRRGISTVIDAASGTFDRSVTLLEVCGSWPEGFGLRHMASMEHTEEGLRERLADAMAESPSRDVVGPGTELQREGSIETLSNSSGSTSGSIPRNFDGYRSPLPTNESQPLSLFPTSFP", "length": 934, "header": "tr|A0AAA9T7D0-1|A0AAA9TT61_BOVIN Computationally mapped isoform of BCAS3 microtubule associated cell migration factor OS=Bos taurus OX=9913 GN=BCAS3 PE=3 SV=1 CANONICAL=A0AAA9TT61-1" }, "locus": { "chromosome": "19", "start_pos": 12296019, "end_pos": 11700368, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000089797.1", "url": "https://www.ensembl.org/id/ENSBTAT00000089797.1" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000091736.1", "url": "https://www.ensembl.org/id/ENSBTAP00000091736.1" } ] } }, { "isoform_ac": "A0AAA9TT61-1", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TT61/entry", "sequence": { "sequence": "MNEEMATDSPRRPSRCTGGVVVRPQAVTEQSYMESVVTFLQDVVPQAYSGTPLTEEKEKIVWVRFENADLNDTSRNLEFHEIHSTGNEPPLLIMIGYSDGMQVWSIPISGEAQELFSVRHGPIRAARILPAPQFGAQKCDNFAEKRPLLGVCKSTGSSGTSPPYCCVDLYSLRTGEMVKSIQFKTPIYDLHCNKRILVVVLQEKIAAFDSCTFTKKFFVTSCYPCPGPNMNPVALGSRWLAYAENKLIRCHQSRGGACGDNIQSYTATVISAAKTLKTGLTMVGKVVTQLTGTLPSGVTEDDVAIHSNSRRSPLVPGIITVIDTETVGEGQVLVSEDSDSDGIVAHFPAHEKPVCCMAFNTSGMLLVTTDTLGHDFHVFQILTHPWSSSQSAVHHLYTLHRGETEAKVQDICFSHDCRWVVVSTLRGTSHVFPINPYGGQPCVRTHMSPRVVNRMSRFQKSAGLEEIEQELTSKQGGRCSPVPGLSSSPSGSPLHGKLNSQDSYNNFANNNPGNPRLSPLPSLMVLMPLAQIKQPMTLGTITKRTGPYLFGAGCFSIKAPCKVKPPPQISPSKSMGGEFCVAATFGTSRSWFANNAGLKREKDQSKQVVVESLYIISCYGTLVEHVMEPRPLSTAPKISDDTPLEMMTSPRASWTLVRTPQWNELQPPFNANHPLLLAADAVQYYQFLLAGLAPPGSPGPITRHGSYDSLASDHSGQEDEEWLSQVEIVTHTGPHRRLWMGPQFQFKTIHPSGQTTVISSSSSVLQSHGPSDTPQPLSDFDTDDLDLNSLRIQPVRSDPVSMPGSSRPVSDRRGISTVIDAASGTFDRSVTLLEVCGSWPEGFGLRHMASMEHTEEGLRERLADAMAESPSRDVVGPGTDTAFEVAVKATTPERHMVVKCVELQREGSIETLSNSSGSTSGSIPRNFDGYRSPLPTNESQPLSLFPTSFP", "length": 950, "header": "tr|A0AAA9TT61-1|A0AAA9TT61_BOVIN Isoform 1 of BCAS3 microtubule associated cell migration factor OS=Bos taurus OX=9913 GN=BCAS3 PE=3 SV=2 CANONICAL=A0AAA9TT61-1" }, "locus": { "chromosome": "19", "start_pos": 12284418, "end_pos": 11700368, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000110692.1", "url": "https://www.ensembl.org/id/ENSBTAT00000110692.1" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000099715.1", "url": "https://www.ensembl.org/id/ENSBTAP00000099715.1" } ] } }, { "isoform_ac": "F1N6R8-1", "url": "https://www.uniprot.org/uniprotkb/F1N6R8/entry", "sequence": { "sequence": "MATDSPRRPSRCTGGVVVRPQAVTEQSYMESVVTFLQDVVPQAYSGTPLTEEKEKIVWVRFENADLNDTSRNLEFHEIHSTGNEPPLLIMIGYSDGMQVWSIPISGEAQELFSVRHGPIRAARILPAPQFGAQKCDNFAEKRPLLGVCKSTGSSGTSPPYCCVDLYSLRTGEMVKSIQFKTPIYDLHCNKRILVVVLQEKIAAFDSCTFTKKFFVTSCYPCPGPNMNPVALGSRWLAYAENKLIRCHQSRGGACGDNIQSYTATVISAAKTLKTGLTMVGKVVTQLTGTLPSGVTEDDVAIHSNSRRSPLVPGIITVIDTETVGEGQVLVSEDSDSDGIVAHFPAHEKPVCCMAFNTSGMLLVTTDTLGHDFHVFQILTHPWSSSQSAVHHLYTLHRGETEAKVQDICFSHDCRWVVVSTLRGTSHVFPINPYGGQPCVRTHMSPRVVNRMSRFQKSAGLEEIEQELTSKQGGRCSPVPGLSSSPSGSPLHGKLNSQDSYNNFANNNPGNPRLSPLPSLMVLMPLAQIKQPMTLGTITKRTGKVKPPPQISPSKSMGGEFCVAATFGTSRSWFANNAGLKREKDQSKQVVVESLYIISCYGTLVEHVMEPRPLSTAPKISDDTPLEMMTSPRASWTLVRTPQWNELQPPFNANHPLLLAADAVQYYQFLLAGLAPPGSPGPITRHGSYDSLASDHSGQEDEEWLSQVEIVTHTGPHRRLWMGPQFQFKTIHPSGQTTVISSSSSVLQSHGPSDTPQPLSDFDTDDLDLNSLRIQPVRSDPVSMPGSSRPVSDRRGISTVIDAASEKLHKYSNPSAEFSASQSGRSISGSFTRPDLTRDRGEIRGSQDLRNIQALLLKF", "length": 858, "header": "tr|F1N6R8-1|F1N6R8_BOVIN Computationally mapped isoform of BCAS3 microtubule associated cell migration factor OS=Bos taurus OX=9913 GN=BCAS3 PE=3 SV=4 CANONICAL=A0AAA9TT61-1" }, "locus": { "chromosome": "19", "start_pos": 12284406, "end_pos": 11918335, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000029909.6", "url": "https://www.ensembl.org/id/ENSBTAT00000029909.6" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000029902.6", "url": "https://www.ensembl.org/id/ENSBTAP00000029902.6" } ] } }, { "isoform_ac": "G3MZ56-1", "url": "https://www.uniprot.org/uniprotkb/G3MZ56/entry", "sequence": { "sequence": "MATDSPRRPSRCTGGVVVRPQAVTEQSYMESVVTFLQDVVPQAYSGTPLTEEKEKIVWVRFENADLNDTSRNLEFHEIHSTGNEPPLLIMIGYSDGMQVWSIPISGEAQELFSVRHGPIRAARILPAPQFGAQKCDNFAEKRPLLGVCKSTGSSGTSPPYCCVDLYSLRTGEMVKSIQFKTPIYDLHCNKRILVVVLQEKIAAFDSCTFTKKFFVTSCYPCPGPNMNPVALGSRWLAYAENKLIRCHQSRGGACGDNIQSYTATVISAAKTLKTGLTMVGKVVTQLTGTLPSGVTEDDVAIHSNSRRSPLVPGIITVIDTETVGEGQVLVSEDSDSDGIVAHFPAHEKPVCCMAFNTSGMLLVTTDTLGHDFHVFQILTHPWSSSQSAVHHLYTLHRGETEAKVQDICFSHDCRWVVVSTLRGTSHVFPINPYGGQPCVRTHMSPRVVNRMSRFQKSAGLEEIEQELTSKQGGRCSPVPGLSSSPSGSPLHGKLNSQDSYNNFANNNPGNPRLSPLPSLMVLMPLAQIKQPMTLGTITKRTGKVKPPPQISPSKSMGGEFCVAATFGTSRSWFANNAGLKREKDQSKQVVVESLYIISCYGTLVEHVMEPRPLSTAPKISDDTPLEMMTSPRASWTLVRTPQWNELQPPFNANHPLLLAADAVQYYQFLLAGLAPPGSPGPITRHGSYDSLASDHSGQEDEEWLSQVEIVTHTGPHRRLWMGPQFQFKTIHPSGQTTVISSSSSVLQSHGPSDTPQPLSDFDTDDLDLNSLRIQPVRSDPVSMPGSSRPVSDRRGISTVIDAASGTFDRSVTLLEVCGSWPEGFGLRHMASMEHTEEGLRERLADAMAESPSRDVVGPGTGKKKKKKTMPTAQRPRTTQQ", "length": 880, "header": "tr|G3MZ56-1|G3MZ56_BOVIN Computationally mapped isoform of BCAS3 microtubule associated cell migration factor OS=Bos taurus OX=9913 GN=BCAS3 PE=3 SV=3 CANONICAL=A0AAA9TT61-1" }, "locus": { "chromosome": "19", "start_pos": 12284406, "end_pos": 11703700, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000063786.3", "url": "https://www.ensembl.org/id/ENSBTAT00000063786.3" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000054849.3", "url": "https://www.ensembl.org/id/ENSBTAP00000054849.3" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [], "orthologs": [], "go_annotation": { "categories": [ { "name": "Biological Process", "total": 6, "go_terms": [ { "name": "angiogenesis", "id": "GO:0001525", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0001525", "evidence": [ { "database": "UniProtKB", "id": "A0AAA9TT61", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TT61" } ], "pmid": "" }, { "name": "DNA-templated transcription", "id": "GO:0006351", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006351", "evidence": [ { "database": "UniProtKB", "id": "A0AAA9TT61", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TT61" } ], "pmid": "" }, { "name": "autophagy", "id": "GO:0006914", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006914", "evidence": [ { "database": "UniProtKB", "id": "A0AAA9TT61", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TT61" } ], "pmid": "" }, { "name": "positive regulation of transcription by RNA polymerase II", "id": "GO:0045944", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0045944", "evidence": [ { "database": "UniProtKB", "id": "A0AAA9TT61", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TT61" } ], "pmid": "" }, { "name": "cellular response to estrogen stimulus", "id": "GO:0071391", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0071391", "evidence": [ { "database": "UniProtKB", "id": "A0AAA9TT61", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TT61" } ], "pmid": "" }, { "name": "response to starvation", "id": "GO:0042594", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0042594", "evidence": [ { "database": "UniProtKB", "id": "A0AAA9TT61", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TT61" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 5, "go_terms": [ { "name": "nucleus", "id": "GO:0005634", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005634", "evidence": [ { "database": "UniProtKB", "id": "A0AAA9TT61", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TT61" } ], "pmid": "" }, { "name": "cytoskeleton", "id": "GO:0005856", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005856", "evidence": [ { "database": "UniProtKB", "id": "A0AAA9TT61", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TT61" } ], "pmid": "" }, { "name": "phagophore assembly site", "id": "GO:0000407", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000407", "evidence": [ { "database": "UniProtKB", "id": "A0AAA9TT61", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TT61" } ], "pmid": "" }, { "name": "euchromatin", "id": "GO:0000791", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000791", "evidence": [ { "database": "UniProtKB", "id": "A0AAA9TT61", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TT61" } ], "pmid": "" }, { "name": "cytoplasm", "id": "GO:0005737", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005737", "evidence": [ { "database": "UniProtKB", "id": "A0AAA9TT61", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TT61" } ], "pmid": "" } ] }, { "name": "Molecular Function", "total": 7, "go_terms": [ { "name": "chromatin binding", "id": "GO:0003682", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003682", "evidence": [ { "database": "UniProtKB", "id": "A0AAA9TT61", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TT61" } ], "pmid": "" }, { "name": "histone binding", "id": "GO:0042393", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0042393", "evidence": [ { "database": "UniProtKB", "id": "A0AAA9TT61", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TT61" } ], "pmid": "" }, { "name": "beta-tubulin binding", "id": "GO:0048487", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0048487", "evidence": [ { "database": "UniProtKB", "id": "A0AAA9TT61", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TT61" } ], "pmid": "" }, { "name": "phosphatidylinositol binding", "id": "GO:0035091", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0035091", "evidence": [ { "database": "UniProtKB", "id": "A0AAA9TT61", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TT61" } ], "pmid": "" }, { "name": "nuclear receptor binding", "id": "GO:0016922", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016922", "evidence": [ { "database": "UniProtKB", "id": "A0AAA9TT61", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TT61" } ], "pmid": "" }, { "name": "acetyltransferase activator activity", "id": "GO:0010698", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0010698", "evidence": [ { "database": "UniProtKB", "id": "A0AAA9TT61", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TT61" } ], "pmid": "" 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"Reactome", "description": "Glutathione conjugation" }, { "id": "R-BTA-9033241", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-BTA-9033241", "resource": "Reactome", "description": "Peroxisomal protein import" } ], "orthologs": [], "go_annotation": { "categories": [ { "name": "Molecular Function", "total": 3, "go_terms": [ { "name": "glutathione transferase activity", "id": "GO:0004364", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0004364", "evidence": [ { "database": "UniProtKB", "id": "A0AAA9TW47", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TW47" } ], "pmid": "" }, { "name": "oxidoreductase activity", "id": "GO:0016491", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016491", "evidence": [ { "database": "UniProtKB", "id": "A0AAA9TW47", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TW47" } ], "pmid": "" }, { "name": "glutathione peroxidase activity", "id": "GO:0004602", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0004602", "evidence": [ { "database": "UniProtKB", "id": "A0AAA9TW47", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TW47" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 3, "go_terms": [ { "name": "cytoplasm", "id": "GO:0005737", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005737", "evidence": [ { "database": "UniProtKB", "id": "A0AAA9TW47", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TW47" } ], "pmid": "" }, { "name": "mitochondrion", "id": "GO:0005739", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005739", "evidence": [ { "database": "UniProtKB", "id": "A0AAA9TW47", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TW47" } ], "pmid": "" }, { "name": "peroxisome", "id": "GO:0005777", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005777", "evidence": [ { "database": "UniProtKB", "id": "A0AAA9TW47", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TW47" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 2, "go_terms": [ { "name": "epithelial cell differentiation", "id": "GO:0030855", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030855", "evidence": [ { "database": "UniProtKB", "id": "A0AAA9TW47", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TW47" } ], "pmid": "" }, { "name": "glutathione metabolic process", "id": "GO:0006749", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006749", "evidence": [ { "database": "UniProtKB", "id": "A0AAA9TW47", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TW47" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 34, "end_pos": 36, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [ { "id": "16437", "name": "", "equation": "RX + glutathione = an S-substituted glutathione + a halide anion + H(+)", "summary": "", "cellular_location": "", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [ "O18879-1", "F1MUX5-1", "F1MX44-1", "A0ABI0P5M0-1", "A0AAA9TW47-1", "F6QEM8-1", "A0ABI0P3R2-1", "A0AAF6Z0W3-1", "P28801-1", "Q2KJG4-1", "A0A3Q1LMV5-1", "F1MVX2-1", "Q28035-1", "Q9N0V4-1", "Q2NL00-1", "F1MXY2-1", "E1BED9-1", "A0ABI0P006-1", "Q5E9G0-1", "Q64L89-1", "A0A452DIU1-1", "F1MGZ9-1", "A0AAA9TXU3-1", "E1BJX2-1" ], "evidence": [ { "id": "16437", "database": "Rhea", "url": "https://www.rhea-db.org/rhea/16437" } ] }, { "id": "R-BTA-3301943", "name": "GSTK1 dimer transfers GS from GSH to CDNB", "equation": "", "summary": "This event has been computationally inferred from an event that has been demonstrated in another species.

The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.

More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "cellular_location": "mitochondrial matrix", "input_participant_list": [ "R-ALL-3301954" ], "output_participant_list": [ "R-ALL-3301969", "R-ALL-3301973" ], "enzyme_list": [ "A0AAA9TW47-1" ], "evidence": [ { "id": "R-BTA-3301943", "database": "Reactome", "url": "https://www.reactome.org/PathwayBrowser/#R-BTA-3301943" } ] }, { "id": "R-BTA-9033235", "name": "Cargo of PEX5S,L translocates from the cytosol to the peroxisomal matrix", "equation": "", "summary": "This event has been computationally inferred from an event that has been demonstrated in another species.

The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.

More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "cellular_location": "peroxisomal membrane", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [ "A0A3Q1LQH8-1", "Q3SZP5-1", "A0AAA9TBR3-1", "A0AAA9TZC7-1", "A0A3Q1LS67-1", "A0AAA9SXG3-1", "F1MYR5-1", "O19094-1", "Q29448-1", "Q3SX23-1", "F1MQP2-1", "F1MVP8-1", "A0AAA9TYP4-1", "Q24K02-1", "F6RWU6-1", "A0A3Q1LTU2-1", "A0A3Q1LYY4-1", "A0AAA9TW47-1", "A0AAA9SND8-1", "F1MV74-1", "P00432-1", "A0A140T8A5-1", "Q29RU9-1", "Q3ZBW2-1", "A0AAA9SC38-1", "A0AAA9SAI8-1" ], "evidence": [ { "id": "R-BTA-9033235", "database": "Reactome", "url": "https://www.reactome.org/PathwayBrowser/#R-BTA-9033235" } ] }, { "id": "R-BTA-9033236", "name": "PEX5S,L:Cargo binds PEX13:PEX14:PEX2:PEX10:PEX12 (Docking and Translocation Module)", "equation": "", "summary": "This event has been computationally inferred from an event that has been demonstrated in another species.

The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.

More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "cellular_location": "peroxisomal membrane", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [ "A0A3Q1LQH8-1", "Q3SZP5-1", "A0AAA9TBR3-1", "A0AAA9TZC7-1", "A0A3Q1LS67-1", "A0AAA9SXG3-1", "F1MYR5-1", "O19094-1", "Q29448-1", "Q3SX23-1", "F1MQP2-1", "F1MVP8-1", "A0AAA9TYP4-1", "Q24K02-1", "F6RWU6-1", "A0A3Q1LTU2-1", "A0A3Q1LYY4-1", "A0AAA9TW47-1", "A0AAA9SND8-1", "F1MV74-1", "P00432-1", "A0A140T8A5-1", "Q29RU9-1", "Q3ZBW2-1", "A0AAA9SC38-1", "A0AAA9SAI8-1" ], "evidence": [ { "id": "R-BTA-9033236", "database": "Reactome", "url": "https://www.reactome.org/PathwayBrowser/#R-BTA-9033236" } ] } ], "reaction_participants": [ { "participant_id": "R-ALL-3301954", "participant_name": "CDNB [mitochondrial matrix]", "crossref": [ { "id": "34718", "database": "ChEBI", "url": "" }, { "id": "ZINC000001540301", "database": "ZINC", "url": "" } ] }, { "participant_id": "R-ALL-3301969", "participant_name": "DNPSG [mitochondrial matrix]", "crossref": [ { "id": "133977", "database": "ChEBI", "url": "" } ] }, { "participant_id": "R-ALL-3301973", "participant_name": "HCl [mitochondrial matrix]", "crossref": [ { "id": "C01327", "database": "COMPOUND", "url": "" }, { "id": "17883", "database": "ChEBI", "url": "" }, { "id": "HMDB0002306", "database": "HMDB Metabolite", "url": "" } ] } ], "reaction_enzymes": [ { "uniprot_ac": "A0A140T8A5", "gene_name": "IDH1", "activity": [ { "ec_number": "1.1.1.42", "activity": "D-threo-isocitrate + NADP(+) = 2-oxoglutarate + CO2 + NADPH.", "evidence": [ { "id": "A0A140T8A5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A140T8A5" } ] }, { "ec_number": "1.1.1.42", "activity": "", "evidence": [ { "id": "A0A140T8A5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A140T8A5" } ] } ] }, { "uniprot_ac": "A0A3Q1LMV5", "gene_name": "LOC281806", "activity": [ { "ec_number": "2.5.1.18", "activity": "RX + glutathione = an S-substituted glutathione + a halide anion + H(+).", "evidence": [ { "id": "A0A3Q1LMV5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1LMV5" } ] }, { "ec_number": "2.5.1.18", "activity": "", "evidence": [ { "id": "A0A3Q1LMV5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1LMV5" } ] } ] }, { "uniprot_ac": "A0A3Q1LQH8", "gene_name": "GNPAT", "activity": [ { "ec_number": "2.3.1.42", "activity": "dihydroxyacetone phosphate + an acyl-CoA = a 1-acylglycerone 3-phosphate + CoA.", "evidence": [ { "id": "A0A3Q1LQH8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1LQH8" } ] }, { "ec_number": "2.3.1.42", "activity": "", "evidence": [ { "id": "A0A3Q1LQH8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1LQH8" } ] } ] }, { "uniprot_ac": "A0A3Q1LS67", "gene_name": "ECH1", "activity": [ { "ec_number": "5.3.3.21", "activity": "a (3E,5Z)-dienoyl-CoA = a (2E,4E)-(5,6-saturated)-dienoyl-CoA.", "evidence": [ { "id": "A0A3Q1LS67", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1LS67" } ] }, { "ec_number": "5.3.3.21", "activity": "", "evidence": [ { "id": "A0A3Q1LS67", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1LS67" } ] } ] }, { "uniprot_ac": "A0A3Q1LTU2", "gene_name": "PEX10", "activity": [ { "ec_number": "2.3.2.27", "activity": "S-ubiquitinyl-[E2 ubiquitin-conjugating enzyme]-L-cysteine + [acceptor protein]-L-lysine = [E2 ubiquitin-conjugating enzyme]-L-cysteine + N(6)-ubiquitinyl-[acceptor protein]-L-lysine.", "evidence": [ { "id": "A0A3Q1LTU2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1LTU2" } ] }, { "ec_number": "2.3.2.27", "activity": "", "evidence": [ { "id": "A0A3Q1LTU2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1LTU2" } ] } ] }, { "uniprot_ac": "A0A3Q1LYY4", "gene_name": "CRAT", "activity": [ { "ec_number": "2.3.1.137", "activity": "octanoyl-CoA + (R)-carnitine = O-octanoyl-(R)-carnitine + CoA.", "evidence": [ { "id": "A0A3Q1LYY4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1LYY4" } ] }, { "ec_number": "2.3.1.7", "activity": "(R)-carnitine + acetyl-CoA = O-acetyl-(R)-carnitine + CoA.", "evidence": [ { "id": "A0A3Q1LYY4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1LYY4" } ] }, { "ec_number": "2.3.1.137", "activity": "", "evidence": [ { "id": "A0A3Q1LYY4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1LYY4" } ] }, { "ec_number": "2.3.1.7", "activity": "", "evidence": [ { "id": "A0A3Q1LYY4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1LYY4" } ] } ] }, { "uniprot_ac": "A0A452DIU1", "gene_name": "LOC327709", "activity": [ { "ec_number": "2.5.1.18", "activity": "RX + glutathione = an S-substituted glutathione + a halide anion + H(+).", "evidence": [ { "id": "A0A452DIU1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A452DIU1" } ] }, { "ec_number": "2.5.1.18", "activity": "", "evidence": [ { "id": "A0A452DIU1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A452DIU1" } ] } ] }, { "uniprot_ac": "A0AAA9SAI8", "gene_name": "TYSND1", "activity": [ { "ec_number": "3.4.21.-", "activity": "", "evidence": [ { "id": "A0AAA9SAI8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9SAI8" } ] } ] }, { "uniprot_ac": "A0AAA9SC38", "gene_name": "HAO1", "activity": [ { "ec_number": "1.1.3.15", "activity": "glycolate + O2 = glyoxylate + H2O2.", "evidence": [ { "id": "A0AAA9SC38", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9SC38" } ] }, { "ec_number": "1.1.3.15", "activity": "", "evidence": [ { "id": "A0AAA9SC38", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9SC38" } ] } ] }, { "uniprot_ac": "A0AAA9SND8", "gene_name": "EHHADH", "activity": [ { "ec_number": "1.1.1.35", "activity": "a (3S)-3-hydroxyacyl-CoA + NAD(+) = a 3-oxoacyl-CoA + NADH + H(+).", "evidence": [ { "id": "A0AAA9SND8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9SND8" } ] }, { "ec_number": "4.2.1.17", "activity": "(3S)-3-hydroxyadipyl-CoA = (E)-2,3-didehydroadipoyl-CoA + H2O.", "evidence": [ { "id": "A0AAA9SND8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9SND8" } ] }, { "ec_number": "5.3.3.8", "activity": "a (3Z)-enoyl-CoA = a 4-saturated (2E)-enoyl-CoA.", "evidence": [ { "id": "A0AAA9SND8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9SND8" } ] }, { "ec_number": "4.2.1.17", "activity": "", "evidence": [ { "id": "A0AAA9SND8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9SND8" } ] }, { "ec_number": "1.1.1.35", "activity": "", "evidence": [ { "id": "A0AAA9SND8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9SND8" } ] }, { "ec_number": "5.3.3.8", "activity": "", "evidence": [ { "id": "A0AAA9SND8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9SND8" } ] } ] }, { "uniprot_ac": "A0AAA9SXG3", "gene_name": "DAO", "activity": [ { "ec_number": "1.4.3.3", "activity": "D-lysine + O2 + H2O = 6-amino-2-oxohexanoate + H2O2 + NH4(+).", "evidence": [ { "id": "A0AAA9SXG3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9SXG3" } ] }, { "ec_number": "1.4.3.3", "activity": "", "evidence": [ { "id": "A0AAA9SXG3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9SXG3" } ] } ] }, { "uniprot_ac": "A0AAA9TBR3", "gene_name": "PAOX", "activity": [ { "ec_number": "1.5.3.13", "activity": "N(1)-acetylspermine + O2 + H2O = 3-acetamidopropanal + spermidine + H2O2.", "evidence": [ { "id": "A0AAA9TBR3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TBR3" } ] }, { "ec_number": "1.5.3.13", "activity": "", "evidence": [ { "id": "A0AAA9TBR3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TBR3" } ] } ] }, { "uniprot_ac": "A0AAA9TW47", "gene_name": "GSTK1", "activity": [ { "ec_number": "2.5.1.18", "activity": "RX + glutathione = an S-substituted glutathione + a halide anion + H(+).", "evidence": [ { "id": "A0AAA9TW47", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TW47" } ] }, { "ec_number": "2.5.1.18", "activity": "", "evidence": [ { "id": "A0AAA9TW47", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TW47" } ] } ] }, { "uniprot_ac": "A0AAA9TXU3", "gene_name": "GSTZ1", "activity": [ { "ec_number": "5.2.1.2", "activity": "4-maleylacetoacetate = 4-fumarylacetoacetate.", "evidence": [ { "id": "A0AAA9TXU3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TXU3" } ] }, { "ec_number": "5.2.1.2", "activity": "", "evidence": [ { "id": "A0AAA9TXU3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TXU3" } ] }, { "ec_number": "2.5.1.18", "activity": "RX + glutathione = an S-substituted glutathione + a halide anion + H(+).", "evidence": [ { "id": "A0AAA9TXU3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TXU3" } ] }, { "ec_number": "2.5.1.18", "activity": "", "evidence": [ { "id": "A0AAA9TXU3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TXU3" } ] } ] }, { "uniprot_ac": "A0AAA9TYP4", "gene_name": "PECR", "activity": [ { "ec_number": "1.3.1.38", "activity": "a (2E)-enoyl-CoA + NADPH + H(+) = a 2,3-saturated acyl-CoA + NADP(+).", "evidence": [ { "id": "A0AAA9TYP4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TYP4" } ] }, { "ec_number": "1.3.1.38", "activity": "", "evidence": [ { "id": "A0AAA9TYP4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TYP4" } ] } ] }, { "uniprot_ac": "A0AAA9TZC7", "gene_name": "ECI2", "activity": [ { "ec_number": "5.3.3.8", "activity": "a (3Z)-enoyl-CoA = a 4-saturated (2E)-enoyl-CoA.", "evidence": [ { "id": "A0AAA9TZC7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TZC7" } ] }, { "ec_number": "5.3.3.8", "activity": "", "evidence": [ { "id": "A0AAA9TZC7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TZC7" } ] } ] }, { "uniprot_ac": "A0AAF6Z0W3", "gene_name": "LANCL1", "activity": [ { "ec_number": "2.5.1.18", "activity": "RX + glutathione = an S-substituted glutathione + a halide anion + H(+).", "evidence": [ { "id": "A0AAF6Z0W3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAF6Z0W3" } ] }, { "ec_number": "2.5.1.18", "activity": "", "evidence": [ { "id": "A0AAF6Z0W3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAF6Z0W3" } ] } ] }, { "uniprot_ac": "A0ABI0P006", "gene_name": "LOC785216", "activity": [ { "ec_number": "1.20.4.2", "activity": "methylarsonate + 2 glutathione + H(+) = methylarsonous acid + glutathione disulfide + H2O.", "evidence": [ { "id": "A0ABI0P006", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0ABI0P006" } ] }, { "ec_number": "1.8.5.1", "activity": "L-dehydroascorbate + 2 glutathione = glutathione disulfide + L-ascorbate.", "evidence": [ { "id": "A0ABI0P006", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0ABI0P006" } ] }, { "ec_number": "2.5.1.18", "activity": "RX + glutathione = an S-substituted glutathione + a halide anion + H(+).", "evidence": [ { "id": "A0ABI0P006", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0ABI0P006" } ] }, { "ec_number": "1.8.5.1", "activity": "", "evidence": [ { "id": "A0ABI0P006", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0ABI0P006" } ] }, { "ec_number": "2.5.1.18", "activity": "", "evidence": [ { "id": "A0ABI0P006", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0ABI0P006" } ] }, { "ec_number": "1.20.4.2", "activity": "", "evidence": [ { "id": "A0ABI0P006", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0ABI0P006" } ] } ] }, { "uniprot_ac": "A0ABI0P3R2", "gene_name": "GSTT2", "activity": [ { "ec_number": "2.5.1.18", "activity": "RX + glutathione = an S-substituted glutathione + a halide anion + H(+).", "evidence": [ { "id": "A0ABI0P3R2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0ABI0P3R2" } ] }, { "ec_number": "2.5.1.18", "activity": "", "evidence": [ { "id": "A0ABI0P3R2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0ABI0P3R2" } ] }, { "ec_number": "4.1.1.84", "activity": "D-dopachrome + H(+) = 5,6-dihydroxyindole + CO2.", "evidence": [ { "id": "A0ABI0P3R2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0ABI0P3R2" } ] }, { "ec_number": "4.1.1.84", "activity": "", "evidence": [ { "id": "A0ABI0P3R2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0ABI0P3R2" } ] } ] }, { "uniprot_ac": "A0ABI0P5M0", "gene_name": "GSTA1", "activity": [ { "ec_number": "2.5.1.18", "activity": "RX + glutathione = an S-substituted glutathione + a halide anion + H(+).", "evidence": [ { "id": "A0ABI0P5M0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0ABI0P5M0" } ] }, { "ec_number": "2.5.1.18", "activity": "", "evidence": [ { "id": "A0ABI0P5M0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0ABI0P5M0" } ] } ] }, { "uniprot_ac": "E1BED9", "gene_name": "GSTO2", "activity": [ { "ec_number": "1.20.4.2", "activity": "methylarsonate + 2 glutathione + H(+) = methylarsonous acid + glutathione disulfide + H2O.", "evidence": [ { "id": "E1BED9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BED9" } ] }, { "ec_number": "1.8.5.1", "activity": "L-dehydroascorbate + 2 glutathione = glutathione disulfide + L-ascorbate.", "evidence": [ { "id": "E1BED9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BED9" } ] }, { "ec_number": "2.5.1.18", "activity": "RX + glutathione = an S-substituted glutathione + a halide anion + H(+).", "evidence": [ { "id": "E1BED9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BED9" } ] }, { "ec_number": "1.20.4.2", "activity": "", "evidence": [ { "id": "E1BED9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BED9" } ] }, { "ec_number": "2.5.1.18", "activity": "", "evidence": [ { "id": "E1BED9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BED9" } ] }, { "ec_number": "1.8.5.1", "activity": "", "evidence": [ { "id": "E1BED9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BED9" } ] } ] }, { "uniprot_ac": "E1BJX2", "gene_name": "GSTT4", "activity": [ { "ec_number": "2.5.1.18", "activity": "RX + glutathione = an S-substituted glutathione + a halide anion + H(+).", "evidence": [ { "id": "E1BJX2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BJX2" } ] }, { "ec_number": "2.5.1.18", "activity": "", "evidence": [ { "id": "E1BJX2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BJX2" } ] } ] }, { "uniprot_ac": "F1MGZ9", "gene_name": "HPGDS", "activity": [ { "ec_number": "5.3.99.2", "activity": "prostaglandin H2 = prostaglandin D2.", "evidence": [ { "id": "F1MGZ9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MGZ9" } ] }, { "ec_number": "2.5.1.18", "activity": "RX + glutathione = an S-substituted glutathione + a halide anion + H(+).", "evidence": [ { "id": "F1MGZ9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MGZ9" } ] }, { "ec_number": "5.3.99.2", "activity": "", "evidence": [ { "id": "F1MGZ9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MGZ9" } ] }, { "ec_number": "2.5.1.18", "activity": "", "evidence": [ { "id": "F1MGZ9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MGZ9" } ] } ] }, { "uniprot_ac": "F1MQP2", "gene_name": "SLC27A2", "activity": [ { "ec_number": "6.2.1.3", "activity": "a long-chain fatty acid + ATP + CoA = a long-chain fatty acyl-CoA + AMP + diphosphate.", "evidence": [ { "id": "F1MQP2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MQP2" } ] }, { "ec_number": "6.2.1.3", "activity": "", "evidence": [ { "id": "F1MQP2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MQP2" } ] } ] }, { "uniprot_ac": "F1MUX5", "gene_name": "LOC100295687", "activity": [ { "ec_number": "2.5.1.18", "activity": "RX + glutathione = an S-substituted glutathione + a halide anion + H(+).", "evidence": [ { "id": "F1MUX5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MUX5" } ] }, { "ec_number": "2.5.1.18", "activity": "", "evidence": [ { "id": "F1MUX5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MUX5" } ] } ] }, { "uniprot_ac": "F1MV74", "gene_name": "SCP2", "activity": [ { "ec_number": "2.3.1.176", "activity": "4,8,12-trimethyltridecanoyl-CoA + propanoyl-CoA = 3-oxopristanoyl-CoA + CoA.", "evidence": [ { "id": "F1MV74", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MV74" } ] }, { "ec_number": "2.3.1.16", "activity": "an acyl-CoA + acetyl-CoA = a 3-oxoacyl-CoA + CoA.", "evidence": [ { "id": "F1MV74", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MV74" } ] }, { "ec_number": "2.3.1.155", "activity": "tetradecanoyl-CoA + acetyl-CoA = 3-oxohexadecanoyl-CoA + CoA.", "evidence": [ { "id": "F1MV74", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MV74" } ] }, { "ec_number": "2.3.1.16", "activity": "", "evidence": [ { "id": "F1MV74", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MV74" } ] }, { "ec_number": "2.3.1.155", "activity": "", "evidence": [ { "id": "F1MV74", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MV74" } ] }, { "ec_number": "2.3.1.176", "activity": "", "evidence": [ { "id": "F1MV74", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MV74" } ] } ] }, { "uniprot_ac": "F1MVP8", "gene_name": "HACL1", "activity": [ { "ec_number": "4.1.2.63", "activity": "2-hydroxy-3-methylhexadecanoyl-CoA = 2-methylpentadecanal + formyl-CoA.", "evidence": [ { "id": "F1MVP8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MVP8" } ] }, { "ec_number": "4.1.2.63", "activity": "", "evidence": [ { "id": "F1MVP8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MVP8" } ] } ] }, { "uniprot_ac": "F1MVX2", "gene_name": "LANCL1", "activity": [ { "ec_number": "2.5.1.18", "activity": "RX + glutathione = an S-substituted glutathione + a halide anion + H(+).", "evidence": [ { "id": "F1MVX2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MVX2" } ] }, { "ec_number": "2.5.1.18", "activity": "", "evidence": [ { "id": "F1MVX2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MVX2" } ] } ] }, { "uniprot_ac": "F1MX44", "gene_name": "GSTA5", "activity": [ { "ec_number": "2.5.1.18", "activity": "RX + glutathione = an S-substituted glutathione + a halide anion + H(+).", "evidence": [ { "id": "F1MX44", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MX44" } ] }, { "ec_number": "2.5.1.18", "activity": "", "evidence": [ { "id": "F1MX44", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MX44" } ] } ] }, { "uniprot_ac": "F1MXY2", "gene_name": "MGST1", "activity": [ { "ec_number": "2.5.1.18", "activity": "RX + glutathione = an S-substituted glutathione + a halide anion + H(+).", "evidence": [ { "id": "F1MXY2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MXY2" } ] }, { "ec_number": "2.5.1.18", "activity": "", "evidence": [ { "id": "F1MXY2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MXY2" } ] } ] }, { "uniprot_ac": "F1MYR5", "gene_name": "NOS2", "activity": [ { "ec_number": "1.14.13.39", "activity": "2 L-arginine + 3 NADPH + 4 O2 + H(+) = 2 L-citrulline + 2 nitric oxide + 3 NADP(+) + 4 H2O.", "evidence": [ { "id": "F1MYR5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MYR5" } ] }, { "ec_number": "1.14.13.39", "activity": "", "evidence": [ { "id": "F1MYR5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MYR5" } ] } ] }, { "uniprot_ac": "F6QEM8", "gene_name": "LOC783879", "activity": [ { "ec_number": "2.5.1.18", "activity": "RX + glutathione = an S-substituted glutathione + a halide anion + H(+).", "evidence": [ { "id": "F6QEM8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F6QEM8" } ] }, { "ec_number": "2.5.1.18", "activity": "", "evidence": [ { "id": "F6QEM8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F6QEM8" } ] } ] }, { "uniprot_ac": "F6RWU6", "gene_name": "ACOT8", "activity": [ { "ec_number": "3.1.2.2", "activity": "hexadecanoyl-CoA + H2O = hexadecanoate + CoA + H(+).", "evidence": [ { "id": "F6RWU6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F6RWU6" } ] }, { "ec_number": "3.1.2.27", "activity": "(3S)-3-hydroxy-3-methylglutaryl-CoA + H2O = 3-hydroxy-3-methylglutarate + CoA + H(+).", "evidence": [ { "id": "F6RWU6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F6RWU6" } ] }, { "ec_number": "3.1.2.1", "activity": "acetyl-CoA + H2O = acetate + CoA + H(+).", "evidence": [ { "id": "F6RWU6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F6RWU6" } ] }, { "ec_number": "3.1.2.11", "activity": "acetoacetyl-CoA + H2O = acetoacetate + CoA + H(+).", "evidence": [ { "id": "F6RWU6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F6RWU6" } ] }, { "ec_number": "3.1.2.3", "activity": "succinyl-CoA + H2O = succinate + CoA + H(+).", "evidence": [ { "id": "F6RWU6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F6RWU6" } ] }, { "ec_number": "3.1.2.5", "activity": "(3S)-3-hydroxy-3-methylglutaryl-CoA + H2O = 3-hydroxy-3-methylglutarate + CoA + H(+).", "evidence": [ { "id": "F6RWU6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F6RWU6" } ] }, { "ec_number": "3.1.2.11", "activity": "", "evidence": [ { "id": "F6RWU6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F6RWU6" } ] }, { "ec_number": "3.1.2.5", "activity": "", "evidence": [ { "id": "F6RWU6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F6RWU6" } ] }, { "ec_number": "3.1.2.27", "activity": "", "evidence": [ { "id": "F6RWU6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F6RWU6" } ] }, { "ec_number": "3.1.2.2", "activity": "", "evidence": [ { "id": "F6RWU6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F6RWU6" } ] }, { "ec_number": "3.1.2.3", "activity": "", "evidence": [ { "id": "F6RWU6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F6RWU6" } ] }, { "ec_number": "3.1.2.1", "activity": "", "evidence": [ { "id": "F6RWU6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F6RWU6" } ] } ] }, { "uniprot_ac": "O18879", "gene_name": "GSTA2", "activity": [ { "ec_number": "2.5.1.18", "activity": "RX + glutathione = an S-substituted glutathione + a halide anion + H(+).", "evidence": [ { "id": "O18879", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/O18879" } ] }, { "ec_number": "2.5.1.18", "activity": "", "evidence": [ { "id": "O18879", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/O18879" } ] } ] }, { "uniprot_ac": "O19094", "gene_name": "CROT", "activity": [ { "ec_number": "2.3.1.137", "activity": "octanoyl-CoA + (R)-carnitine = O-octanoyl-(R)-carnitine + CoA.", "evidence": [ { "id": "O19094", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/O19094" } ] }, { "ec_number": "2.3.1.137", "activity": "", "evidence": [ { "id": "O19094", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/O19094" } ] } ] }, { "uniprot_ac": "P00432", "gene_name": "CAT", "activity": [ { "ec_number": "1.11.1.6", "activity": "2 H2O2 = O2 + 2 H2O.", "evidence": [ { "id": "P00432", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P00432" } ] }, { "ec_number": "1.11.1.6", "activity": "", "evidence": [ { "id": "P00432", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P00432" } ] } ] }, { "uniprot_ac": "P28801", "gene_name": "GSTP1", "activity": [ { "ec_number": "2.5.1.18", "activity": "RX + glutathione = an S-substituted glutathione + a halide anion + H(+).", "evidence": [ { "id": "P28801", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P28801" } ] }, { "ec_number": "2.5.1.18", "activity": "", "evidence": [ { "id": "P28801", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P28801" } ] } ] }, { "uniprot_ac": "Q24K02", "gene_name": "IDE", "activity": [ { "ec_number": "3.4.24.56", "activity": "Degradation of insulin, glucagon and other polypeptides. No action on proteins.", "evidence": [ { "id": "Q24K02", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q24K02" } ] }, { "ec_number": "3.4.24.56", "activity": "", "evidence": [ { "id": "Q24K02", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q24K02" } ] } ] }, { "uniprot_ac": "Q28035", "gene_name": "GSTA1", "activity": [ { "ec_number": "1.11.1.-", "activity": "", "evidence": [ { "id": "Q28035", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q28035" } ] }, { "ec_number": "5.3.3.-", "activity": "", "evidence": [ { "id": "Q28035", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q28035" } ] }, { "ec_number": "2.5.1.18", "activity": "RX + glutathione = an S-substituted glutathione + a halide anion + H(+).", "evidence": [ { "id": "Q28035", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q28035" } ] }, { "ec_number": "2.5.1.18", "activity": "", "evidence": [ { "id": "Q28035", "database": 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} ] }, { "ec_number": "1.5.3.1", "activity": "", "evidence": [ { "id": "Q29RU9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q29RU9" } ] }, { "ec_number": "1.5.3.7", "activity": "", "evidence": [ { "id": "Q29RU9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q29RU9" } ] } ] }, { "uniprot_ac": "Q2KJG4", "gene_name": "MGST2", "activity": [ { "ec_number": "1.11.1.-", "activity": "", "evidence": [ { "id": "Q2KJG4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q2KJG4" } ] }, { "ec_number": "4.4.1.20", "activity": "leukotriene C4 = leukotriene A4 + glutathione.", "evidence": [ { "id": "Q2KJG4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q2KJG4" } ] }, { "ec_number": "2.5.1.18", "activity": "RX + glutathione = an S-substituted glutathione + a halide anion + H(+).", "evidence": [ { "id": "Q2KJG4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q2KJG4" } ] }, { "ec_number": "2.5.1.18", 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"binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 158, "end_pos": 160 }, { "start_pos": 192, "end_pos": 194 }, { "start_pos": 217, "end_pos": 219 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": 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}, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ], "tool_support": { "graph_view": "yes" } }, { "uniprot_canonical_ac": "A0AAA9TU17-1", "uniprot_ac": "A0AAA9TU17", "uniprot_id": "A0AAA9TU17_BOVIN", "mass": { "chemical_mass": 86314.0, "monoisotopic_mass": 86314.0 }, "refseq": { "ac": "NP_001193146", "name": "pleckstrin homology domain-containing family M member 3", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001193146" }, "gene_names": [ { "name": "PLEKHM3", "type": "recommended", "evidence": [ { "id": "A0AAA9TU17", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TU17" } ] }, { "name": "PLEKHM1L", "type": "synonym", "evidence": [ { "id": "NP_001193146", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001193146" } ] }, { "name": "PLEKHM3", "type": "synonym", "evidence": [ { "id": "NP_001193146", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001193146" } ] } ], "protein_names": [ { "name": "Pleckstrin homology domain-containing family M member 3", "type": "recommended", "evidence": [ { "id": "A0AAA9TU17", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TU17/entry#names_and_taxonomy" } ] }, { "name": "pleckstrin homology domain containing, family M, member 3", "type": "synonym", "evidence": [ { "id": "NP_001193146", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001193146" } ] }, { "name": "pleckstrin homology domain-containing family M member 3", "type": "synonym", "evidence": [ { "id": "NP_001193146", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001193146" } ] } ], "function": [ { "annotation": "Involved in skeletal muscle differentiation. May act as a scaffold protein for AKT1 during muscle differentiation.", "evidence": [ { "database": "UniProtKB", "id": "A0AAA9SN44", "url": "https://www.uniprot.org/uniprotkb/A0AAA9SN44#function" }, { "database": "UniProtKB", "id": "ARBA00054394", "url": "https://www.uniprot.org/uniprotkb/ARBA00054394#function" }, { "database": "UniProtKB", "id": "F1MPG9", "url": "https://www.uniprot.org/uniprotkb/F1MPG9#function" }, { "database": "UniProtKB", "id": "A0AAA9TU17", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TU17#function" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Bos taurus", "taxid": 9913, "evidence": [ { "database": "UniProtKB", "id": "A0AAA9TU17", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TU17" } ], "common_name": "Bovine", "glygen_name": "Bovine", "reference_species": "Bos taurus [9913]" } ], "gene": [ { "name": "PLEKHM3", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TU17", "locus": { "chromosome": "2", "start_pos": 96100251, "end_pos": 96318495, "strand": "+", "evidence": [ { "database": "Ensembl Gene", "id": "ENSBTAG00000007830", "url": "https://www.ensembl.org/id/ENSBTAG00000007830" } ] } } ], "crossref": [ { "id": "A0AAA9TU17", "url": "https://alphafold.ebi.ac.uk/entry/A0AAA9TU17", "database": "AlphaFoldDB", "categories": [] }, { "id": "ENSBTAG00000007830", "url": "https://bgee.org/?page=gene&gene_id=ENSBTAG00000007830", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "cd14674", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd14674", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "533312", "url": "https://www.ncbi.nlm.nih.gov/gene/533312", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR001849", "url": "https://www.ebi.ac.uk/interpro/entry/IPR001849", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR011993", "url": "https://www.ebi.ac.uk/interpro/entry/IPR011993", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR025258", "url": "https://www.ebi.ac.uk/interpro/entry/IPR025258", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR037812", "url": "https://www.ebi.ac.uk/interpro/entry/IPR037812", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR051366", "url": "https://www.ebi.ac.uk/interpro/entry/IPR051366", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "bta:533312", "url": "https://www.genome.jp/dbget-bin/www_bget?bta:533312", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "CVHRELH", "url": "https://omabrowser.org/oma/group/CVHRELH/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "F1MPG9", "url": "https://www.orthodb.org/?gene=F1MPG9", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR12326", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR12326", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR12326:SF10", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR12326:SF10", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00169", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00169", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF13901", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF13901", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "NP_001193146", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001193146", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0AAA9SN44", "url": "https://www.uniprot.org/uniprotkb/A0AAA9SN44", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0AAA9SN44-1", "url": "https://www.uniprot.org/uniprotkb/A0AAA9SN44-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0AAA9TU17", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TU17", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0AAA9TU17-1", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TU17-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "F1MPG9", "url": "https://www.uniprot.org/uniprotkb/F1MPG9", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "F1MPG9-1", "url": "https://www.uniprot.org/uniprotkb/F1MPG9-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MEALEVDDISPALEVTEDFFNTFDNKLEKAVQQAEVYGIQEVPELVGREVLGNIDNGAIRNVTSLGQGGVIWDHCKTRLLDTKVPNVFPAKEQFMVQKGTTPDNLSWMEQKEASTFNFFNICQRRRDRPRSVNDLLDETSTFKPGHARSRSDITQVDWRVVLKTMPLQQEVSLQGPHFARPSLLLSSSNKVEDAQGNTEHKPAFPNILKKGYLEIRKEHDSYWQSCYAELSPYSLYFYSLDSSGNQNLYATYQLSHFQSISVLGNLEARLVDTVLYDNTQLQLKAESPWEALDWGQKLWEGVHAAAPAYMGRPGELANSPGLGHHVDCPQNHCLQKKSRELLMPSPVLDSPKQYQNILKSGTLYRLTMQNNWKAFTFVLSRTCLMAFPPGKLDEDPLLSYNVDVCLAVQLDHLDDCDSCFQVIFPQDVLRLRAETRQRAQEWMEALKTAANTARSSEQNLQVTLRTKPRDQMGGHELRKNKRQSVTTSFLSILTTLSLERGLTAQSFKCAGCQRSIGLSNGKAKVCSYSGWYYCSSCHVDDSFLIPARIVHNWDTSKYKVSKQAKEFLEYVYEEPLIDIQQQNPMLYGHAEPLATVVRLRQRLKSLRAYLFSCRAAVAEDLRRRIFPREYLLQQIHLYSLADLQQVIEGKLAPFLGKVIKFATSHVYSCSLCSQKGFICEICNNGEILYPFEDISTSRCESCGAVFHAECKEKSVPCPRCVRRELQMKQKSFWRRLNMDESLEEACNMFELSYQNT", "length": 756, "header": "tr|A0AAA9TU17-1|A0AAA9TU17_BOVIN Isoform 1 of Pleckstrin homology domain-containing family M member 3 OS=Bos taurus OX=9913 GN=PLEKHM3 PE=4 SV=1 CANONICAL=A0AAA9TU17-1" }, "isoforms": [ { "isoform_ac": "A0AAA9SN44-1", "url": "https://www.uniprot.org/uniprotkb/A0AAA9SN44/entry", "sequence": { "sequence": "MEALEVDDISPALEVTEDFFNTFDNKLEKAVQQAEVYGIQEVPELVGREVLGNIDNGAIRNVTSLGQGGVIWDHCKTRLLDTKVPNVFPAKEQFMVQKGTTPDNLSWMEQKEASTFNFFNICQRRRDRPRSVNDLLDETSTFKPGHARSRSDITQVDWRVVLKTMPLQQEVSLQGPHFARPSLLLSSSNKVEDAQGNTEHKPAFPNILKKGYLEIRKEHDSYWQSCYAELSPYSLYFYSLDSSGNQNLYATYQLSHFQSISVLGNLEARLVDTVLYDNTQLQLKAESPWEALDWGQKLWEGVHAAAPAYMGRPGELANSPGLGHHVDCPQNHCLQKKSRELLMPSPVLDSPKQYQNILKSGTLYRLTMQNNWKAFTFVLSRTCLMAFPPGKLDEDPLLSYNVDVCLAVQLDHLDDCDSCFQVIFPQDVLRLRAETRQRAQEWMEALKTAANTARSSEQNLQVTLRTKPRDQMGGHELRKNKRQSVTTSFLSILTTLSLERGLTAQSFKCAGCQRSIGLSNGKAKVCSYSGWYYCSSCHVDDSFLIPARIVHNWDTSKYKVSKQAKEFLEYVYEEPLIDIQQQNPMLYGHAEPLATVVRLRQRLKSLRAYLFSCRAAVAEDLRRRIFPREYLLQQIHLYSLADLQQVIEGKLAPFLGKVIKFATSHVYSCSLCSQKGFICEICNNGEILYPFEDISTSRTSQVPQW", "length": 705, "header": "tr|A0AAA9SN44-1|A0AAA9TU17_BOVIN Computationally mapped isoform of Pleckstrin homology domain-containing family M member 3 OS=Bos taurus OX=9913 GN=PLEKHM3 PE=4 SV=1 CANONICAL=A0AAA9TU17-1" }, "locus": { "chromosome": "2", "start_pos": 96288713, "end_pos": 96126670, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000106749.1", "url": "https://www.ensembl.org/id/ENSBTAT00000106749.1" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000087755.1", "url": "https://www.ensembl.org/id/ENSBTAP00000087755.1" } ] } }, { "isoform_ac": "A0AAA9TU17-1", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TU17/entry", "sequence": { "sequence": "MEALEVDDISPALEVTEDFFNTFDNKLEKAVQQAEVYGIQEVPELVGREVLGNIDNGAIRNVTSLGQGGVIWDHCKTRLLDTKVPNVFPAKEQFMVQKGTTPDNLSWMEQKEASTFNFFNICQRRRDRPRSVNDLLDETSTFKPGHARSRSDITQVDWRVVLKTMPLQQEVSLQGPHFARPSLLLSSSNKVEDAQGNTEHKPAFPNILKKGYLEIRKEHDSYWQSCYAELSPYSLYFYSLDSSGNQNLYATYQLSHFQSISVLGNLEARLVDTVLYDNTQLQLKAESPWEALDWGQKLWEGVHAAAPAYMGRPGELANSPGLGHHVDCPQNHCLQKKSRELLMPSPVLDSPKQYQNILKSGTLYRLTMQNNWKAFTFVLSRTCLMAFPPGKLDEDPLLSYNVDVCLAVQLDHLDDCDSCFQVIFPQDVLRLRAETRQRAQEWMEALKTAANTARSSEQNLQVTLRTKPRDQMGGHELRKNKRQSVTTSFLSILTTLSLERGLTAQSFKCAGCQRSIGLSNGKAKVCSYSGWYYCSSCHVDDSFLIPARIVHNWDTSKYKVSKQAKEFLEYVYEEPLIDIQQQNPMLYGHAEPLATVVRLRQRLKSLRAYLFSCRAAVAEDLRRRIFPREYLLQQIHLYSLADLQQVIEGKLAPFLGKVIKFATSHVYSCSLCSQKGFICEICNNGEILYPFEDISTSRCESCGAVFHAECKEKSVPCPRCVRRELQMKQKSFWRRLNMDESLEEACNMFELSYQNT", "length": 756, "header": "tr|A0AAA9TU17-1|A0AAA9TU17_BOVIN Isoform 1 of Pleckstrin homology domain-containing family M member 3 OS=Bos taurus OX=9913 GN=PLEKHM3 PE=4 SV=1 CANONICAL=A0AAA9TU17-1" }, "locus": { "chromosome": "2", "start_pos": 96288713, "end_pos": 96101255, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000118990.1", "url": "https://www.ensembl.org/id/ENSBTAT00000118990.1" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000100038.1", "url": "https://www.ensembl.org/id/ENSBTAP00000100038.1" } ] } }, { "isoform_ac": "F1MPG9-1", "url": "https://www.uniprot.org/uniprotkb/F1MPG9/entry", "sequence": { "sequence": "MEALEVDDISPALEVTEDFFNTFDNKLEKAVQQAEVYGIQEVPELVGREVLGNIDNGAIRNVTSLGQGGVIWDHCKTRLLDTKVPNVFPAKEQFMVQKGTTPDNLSWMEQKEASTFNFFNICQRRRDRPRSVNDLLDETSTFKPGHARSRSDITQVDWRVVLKTMPLQQEVSLQGPHFARPSLLLSSSNKVEDAQGNTEHKPAFPNILKKGYLEIRKEHDSYWQSCYAELSPYSLYFYSLDSSGNQNLYATYQLSHFQSISVLGNLEARLVDTVLYDNTQLQLKAESPWEALDWGQKLWEGVHAAAPAYMGRPGELANSPGLGHHVDCPQNHCLQKKSRELLMPSPVLDSPKQYQNILKSGTLYRLTMQNNWKAFTFVLSRTCLMAFPPGKLDEDPLLSYNVDVCLAVQLDHLDDCDSCFQVIFPQDVLRLRAETRQRAQEWMEALKTAANTARSSEQNLQVTLRTKPRDQMGGHELRKNKRQSVTTSFLSILTTLSLERGLTAQSFKCAGCQRSIGLSNGKAKVCSYSGWYYCSSCHVDDSFLIPARIVHNWDTSKYKVSKQAKEFLEYVYEEPLIDIQQQNPMLYGHAEPLATVVRLRQRLKSLRAYLFSCRAAVAEDLRRRIFPREYLLQQIHLYSLADLQQVIEGKLAPFLGKVIKFATSHVYSCSLCSQKGFICEICNNGEILYPFEDISTSSSVQLLLCPTLRPHELQHARPLCPSPTPGVHSDSCPSSL", "length": 736, "header": "tr|F1MPG9-1|A0AAA9TU17_BOVIN Computationally mapped isoform of Pleckstrin homology domain-containing family M member 3 OS=Bos taurus OX=9913 GN=PLEKHM3 PE=4 SV=3 CANONICAL=A0AAA9TU17-1" }, "locus": { "chromosome": "2", "start_pos": 96288713, "end_pos": 96113916, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000010299.6", "url": "https://www.ensembl.org/id/ENSBTAT00000010299.6" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000010299.6", "url": "https://www.ensembl.org/id/ENSBTAP00000010299.6" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [ { "id": "bta:533312", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?bta:533312", "resource": "KEGG Pathway" } ], "orthologs": [ { "uniprot_canonical_ac": "A0A8V1A9S0-1", "protein_name": "Pleckstrin homology domain containing M3", "gene_name": "PLEKHM3", "tax_id": 9031, "organism": "Gallus gallus", "sequence": { "sequence": "MEALEVDDISPALEVTEDFFNSFDTKLEKIVQPSGVFGVQDVPELVGHEVFDQITESRNLRNVASLAKSSLIWDHCKNGLLETKAQTVFSAKDQHVVQRGTAADNRAWAGEGETAAFNIFNICQRRRDRPRSVNDILVQNEEASTFKPGHNRSRSDISHVNWGVVFTGTSLQQPALPGQDNNCALLSYLALTKGQDIQGNTEHKPTFPNILKKGYLEIRRDNDSYWQTCYAELSPYKLYLYCLDSSGNQTLPTVYPLMHFQRVTVTGSIEAKVVEAVLSDNSQLQLKAESSWEALDWGRKLWEVMRASVSTFTRQPEQVENVPEPDNSSDRSQTNGLVEKPVELLLSMNLTENTKEYQNILKSGTLYRLTVQNNWKAFTFVLNRSYLMAFQPGRLDEDPLLSYNVDVCLSVQTDTQDGCDSCFQVIFPQDVLRLRAETRQRAQEWMEALKTAANVTRSLGQNPQVTLRNKRGDRPFGNDFRKSKRQSVTTSFLSILTTLSLERGLTVQSFKCCQRSIGLSNGKAKVCSYSGWYYCCTCHVDDSFLIPARLVHNWDTSKYKVSKQAKEFLEYVYEEPLIDIQQENPMLYKHVESLATVVRLRQQLKSLRAYLFSCRAAVAEDLRRRIFPREYLLQQIHLYSLADLQQVIEGKLAPFLGKVIKFATSHVYSCSLCSQKGFICEICNNGEILYPFEDISTSRCESCGAVFHSECKVKAVPCPRCVRKELQKKQKSFWRRLNMDENFEESCNMFELSYQNT", "length": 757 }, "evidence": [ { "id": "A0AAA9TU17", "url": "https://omabrowser.org/oma/group/A0AAA9TU17/", "database": "OMA" } ], "glygen_name": "Chicken", "common_name": "Chicken" }, { "uniprot_canonical_ac": "A0ABK0L3E5-1", "protein_name": "Pleckstrin homology domain-containing family M member 3", "gene_name": "Plekhm3", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MEALEVDDISPALEVTEDFFSTFDSKLGKAVQQAEVYGVQEVPELVGHEVLGNITDNGALRSVASLGKGTMIWDHCKSRLLETKAQNVFPAKEQLMVQRGTAPDNLSWMEQKEASTFNFFNICQRRRDRPRSVNDLLDETTTFKPGHARSRSDVTHVDWRVVLSTMPLQQQQQQQQASLHGPHFPRPSFLLSSSNKVEDAQGNTEHKQTFPNILKKGYLEIRKNHDSYWQSCYAELSPYNLNFYSLDSSGNQNLYATYQLSHFQSISVLGNLEARMVDTVLYDNSQLQLKAESPWEALDWGQKLWEVVHAAVPNYMARQEEKANSPGLGHHVDCAQNHCLQKKSSGLLASPVLDSPKQYQNILKSGTLYRLTVQNNWKAFTFVLSKAYLMAFHPGKLDEDPLLSYNVDVCLAVQTDNLDGCDSCFQVIFPQDVLRLRAETRQRAQEWMEALKTAANAARSSEQNLQVTLRNKPKDQLGGHELRKNKRQSVTTSFLSILTTLSLERGLTAQSFKCAGCQRPIGLSNGKAKVCNYSGWYYCSSCHVDDSFLIPARIVHNWDTSKYKVSKQAKEFLEYVYEEPLIDIQQENPMLYLHAEPLATVARLRQRLKSLRAYLFSCRAAVAEDLRRRIFPREYLLQQIHLYSLADLQQVIEGKLAPFLGKVIKFATAHVYSCSLCSQKGFICEICNNGEILYPFEDISTSRCESCGSVFHSECKEKSVPCPRCVRRELQKKQKSFWRQLNVDESLEEACTMFELSYQNT", "length": 761 }, "evidence": [ { "id": "A0AAA9TU17", "url": "https://omabrowser.org/oma/group/A0AAA9TU17/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "G3HU57-1", "protein_name": "Pleckstrin homology domain-containing family M member 3", "gene_name": "Plekhm3", "tax_id": 10029, "organism": "Cricetulus griseus", "sequence": { "sequence": "MEALEVDDISPALEVTEDFFSTFDSKLEKAVQQAEVYGIQEVPELVGHEVFSNITDNGALRNVVSLGSKGNMIWDHCKSRLLETKAQNVFPAKEQLMVQRGTAPDNLSWMEQKEASTFNFFNICQRRRDRPRSVNDLLDESTTFKPGHARSRSDVTHVDWRLVLGTMPLQQQQLSLQGPHFARPSFLLPSPSKVEDAQGNTEHKQTFPNILKKGYLEIRKNHDSYWQSCYAELSPYNLHFYSLDSSGNQSLYATYQLSQFQSISVLGNLEARMVDTVLSDNSQLQLKAESPWEALDWGQKLWEVVHAAAPNYMGRPDEPANSPGLGSQNHCLQKKSSGLLSSPVLHSPKQYQNILKSGTLYRLTVQNNWKAFTFVLSKAYLMAFHPGKLDEDPLLSYNVDVCLAVQIDNLDGCDSCFQVIFPQDVLRLRAETRQRAQEWMEALKTAANAARSSEQNLQVTLRNKPKDQIGGHELRKNKRQSVTTSFLSILTTLSLERGLTAQSFKCAGCQRSIGLSNGKAKVCNYSGWYYCSSCHVDDSFLIPARVVHNWDTSKYKVSKQAKEFLEYVYEEPLIDIQQENPMLYLHAEPLATVVRLRQQLKSLRAYLFSCRAAVAEDLRRRIFPREYLLQQIHLYSLADLQQVIEGKLAPFLGKVIKFATSHVYSCSLCSQKGFICEICNNGEILYPFEDISTSRCESCGAVFHSECKEKSVPCPRCVRRELQKKQKSFWRQLNVDESLEEACTMFELSYQNT", "length": 753 }, "evidence": [ { "id": "A0AAA9TU17", "url": "https://omabrowser.org/oma/group/A0AAA9TU17/", "database": "OMA" } ], "glygen_name": "Hamster", "common_name": "Chinese hamster" }, { "uniprot_canonical_ac": "I3L6K9-1", "protein_name": "Pleckstrin homology domain-containing family M member 3", "gene_name": "PLEKHM3", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MEALEVDDISPALEVTEEFFSTFDSKLEKAVQHAEVYGIQEVPELVGHEVLGNIDNGAIRNVSSLGRGAVIWDHCKSRLLETKAQNVFPAKEQFTVQKGTTPDNLSWMEQKEASTFNFFNICQRRKDRPRSVNDLLDETSTFKPGHARSRSDITQVDWRVGLKTTPLQQQQQQQPSLLGSHFTRPSFLLPSSNKVEDAQGNTEHKQAFPNILKKGYLEIRKNHDSYWQSCYAELSPYNLYFYSLDSSGNQNLYATYQLSHFQSISVLGNLEARLVDTVLYDNTQLQLKAESPWEALDWGQKLWEGVHAAVPAYLGRPDELANSPGLGHHVDCAQNHCLQKKSSQLLMPSPVLDGPKQYQNILKSGTLYRLTVQNNWKAFTFVLSRSYLMAFQPGKLDEDPLLSYNVDVCLAVQLDNLDDCDSCFQVIFPQDVLRLRAETRQRAQEWMEALKTAANAARSSEQNPQVTLRSKPKDQMGGHELRKNKRQSVTTSFLSILTTLSLERGLTAQSFKCAGCQRSIGLSYGKAKVCNYSGWYYCSSCHVDDSFLIPARIVHNWDTSKYKVSKQAKEFLEYVFEEPLIDIQQENPMLYGHAEPLATVVRLRQRLKSLRAYLFSCRAAVAEDLRRRIFPREYLLQQIHLYSLADLQQVIEGKLAPFLGKIIKFATSHVYSCSLCSQKGFICEICNNGEILYPFEDISTSRCESCGAVFHSECKEKSVPCPRCVRRELQKKQKSFWRRLNMDESLEEACNMFELSYQNT", "length": 760 }, "evidence": [ { "id": "A0AAA9TU17", "url": "https://omabrowser.org/oma/group/A0AAA9TU17/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "Q6ZWE6-1", "protein_name": "Pleckstrin homology domain-containing family M member 3", "gene_name": "PLEKHM3", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MEALEVDDISPALEVTEEFFSTLDSNLEKAVQQAEVYGIQEVPELVGHEVLSNITDNGAMRNVTSLGKGGMIWDHCKSRLLETKAQNVFPAKEQFMVQRGTTPDNLSWMEQKEASTFNFFNICQRRRDRPRSVNDLLDETSTFKPGHARSRSDITQVDWRVVLKTTPLQQQQQQQPLLQGPHVTRPSFLLPSPNKIEDAQGNTEHKQTFPNILKKGYLEIRKDHDSYWQSCYAELSPYNLYFYSLDSSGNQNLYATYQLSHFQSISVLGNLEARMVDTVLYDNTQLQLKAESPWEALDWGQKLWEVVHAAVPGYMGRQNELTISPGLGHHDDYTQNHSFQKKTSGLLPPSPVLDSSKQYQNILKSGTLYRLTVQNNWKAFTFVLSRAYLMAFQPGKLDEDPLLSYNVDVCLAVQMDNLDGCDSCFQVIFPQDVLRLRAETRQRAQEWMEALKIAANVARSSEQNLQVTLRNKPKDQMGGHELRKNKRQSVTTSFLSILTTLSLERGLTAQSFKCAGCQRSIGLSNGKAKVCNYSGWYYCSSCHVDDSFLIPARIVHNWDTSKYKVSKQAKEFLEYVYEEPLIDIQQENAMLYHHAEPLAAVLRLRQRLKSLRAYLFSCRAAVAEDLRRRIFPREYLLQQIHLYSLADLQQVIEGKLAPFLGKVIKFATSHVYSCSLCSQKGFICEICNNGEILYPFEDISTSRCESCGAVFHSECKEKSVPCPRCVRRELQKKQKSFWQRLNMDESLEEACTMFELSYQNT", "length": 761 }, "evidence": [ { "id": "A0AAA9TU17", "url": "https://omabrowser.org/oma/group/A0AAA9TU17/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "Q8BM47-1", "protein_name": "Pleckstrin homology domain-containing family M member 3", "gene_name": "Plekhm3", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MEALEVDDISPALEVTEDFFSTFDSKLEKAVQQAEVYGIQEVPELVGHEVLGNIADNGALRSVASLGKGTMIWDHCKSRLLETKAQNVFPAKEQLMVQRGTAPDNLSWMAQKEASTFNFFNICQRRRDRPRSVNDLLDETTTFKPGHARSRSDVTHVDWRVVLSTMPLQQQQQQQQASLQGIHFPGPSFLLSSPSKVEDAQGNTEHKQTFPNILKKGYLEIRKNHDSYWQSCYAELSPYNLNFYSLDSSGNQNLYATYQLSHFQSISVLGNLEARMVDTVLYDNSQLQLKAESPWEALDWGQKLWEVVHAAVPNYMGRQGEMANSPGLIHHGDCAQNHCLQKKSSGLLASPVLDSPKQYQNILKSGTLYRLTVQNNWKAFTFVLSKAYLMAFHPGKLDEDPLLSYNVDVCLAVQIDNLDGCDSCFQVIFPQDVLRLRAETRQRAQEWMEALKTAANAARSSEQNLQVTLRNKPKDQLDGRELRKNKRQSVTTSFLSILTTLSLERGLTAQSFKCAGCQRSIGLSNGKAKVCNYSGWYYCSSCHVDDSFLIPARIVHNWDTSKYKVSKQAKEFLEYVYEEPLIDIQQENPMLYLHAEPLATVVRLRQRLKSLRAYLFSCRAAVAEDLRRRIFPREYLLQQIHLYSLADLQQVIEGKLAPFLGKVIKFATAHVYSCSLCSQKGFICEICNNGEILYPFEDISTSRCESCGAVFHSECKEKSVPCPRCVRRELQKKQKSFWRQLNVDESLEEACAMFELSYQST", "length": 761 }, "evidence": [ { "id": "A0AAA9TU17", "url": "https://omabrowser.org/oma/group/A0AAA9TU17/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" } ], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 2, "go_terms": [ { "name": "Golgi apparatus", "id": "GO:0005794", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005794", "evidence": [ { "database": "UniProtKB", "id": "A0AAA9TU17", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TU17" } ], "pmid": "" }, { "name": "plasma membrane", "id": "GO:0005886", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005886", "evidence": [ { "database": "UniProtKB", "id": "A0AAA9TU17", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TU17" } ], "pmid": "" } ] }, { "name": "Molecular Function", "total": 1, "go_terms": [ { "name": "zinc ion binding", "id": "GO:0008270", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008270", "evidence": [ { "database": "UniProtKB", "id": "A0AAA9TU17", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TU17" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 1, "go_terms": [ { "name": "myoblast differentiation", "id": "GO:0045445", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0045445", "evidence": [ { "database": "UniProtKB", "id": "A0AAA9TU17", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TU17" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 104, "end_pos": 106, "annotation": "n_glycosylation_sequon" }, { "start_pos": 61, "end_pos": 63, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A0AAA9TU17", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TU17" }, { "id": "PS50003", "database": "PROSITE", "url": "https://prosite.expasy.org/PS50003" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "PH", "eco_id": "ECO_0000259", "start_pos": 356, "end_pos": 451, "start_aa": "Asn", "end_aa": "Asn", "glycosite_overlap": [] } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" }, { "name": "homologset.oma", "label": "OMA Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 104, "end_pos": 106 }, { "start_pos": 61, "end_pos": 63 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ], "tool_support": { "graph_view": "yes" } }, { "uniprot_canonical_ac": "A0AAA9TVP8-1", "uniprot_ac": "A0AAA9TVP8", "uniprot_id": "A0AAA9TVP8_BOVIN", "mass": { "chemical_mass": 82512.0, "monoisotopic_mass": 82512.0 }, "refseq": { "ac": "XP_059745020", "name": "FYVE, RhoGEF and PH domain-containing protein 3 isoform X2", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_059745020" }, "gene_names": [ { "name": "FGD3", "type": "recommended", "evidence": [ { "id": "A0AAA9TVP8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TVP8" } ] }, { "name": "FGD3", "type": "synonym", "evidence": [ { "id": "XP_059745020", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_059745020" } ] } ], "protein_names": [ { "name": "FYVE, RhoGEF and PH domain containing 3", "type": "synonym", "evidence": [ { "id": "A0AAA9TVP8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TVP8/entry#names_and_taxonomy" } ] }, { "name": "FYVE, RhoGEF and PH domain-containing protein 3 isoform X2", "type": "synonym", "evidence": [ { "id": "XP_059745020", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_059745020" } ] } ], "function": [], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Bos taurus", "taxid": 9913, "evidence": [ { "database": "UniProtKB", "id": "A0AAA9TVP8", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TVP8" } ], "common_name": "Bovine", "glygen_name": "Bovine", "reference_species": "Bos taurus [9913]" } ], "gene": [ { "name": "FGD3", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TVP8", "locus": { "chromosome": "8", "start_pos": 84420934, "end_pos": 84387632, "strand": "-", "evidence": [ { "database": "Ensembl Gene", "id": "ENSBTAG00000006939", "url": "https://www.ensembl.org/id/ENSBTAG00000006939" } ] } } ], "crossref": [ { "id": "A0AAA9TVP8", "url": "https://alphafold.ebi.ac.uk/entry/A0AAA9TVP8", "database": "AlphaFoldDB", "categories": [] }, { "id": "cd00160", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd00160", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "cd13236", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd13236", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "cd13387", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd13387", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "cd15740", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd15740", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "512950", "url": "https://www.ncbi.nlm.nih.gov/gene/512950", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR000219", "url": "https://www.ebi.ac.uk/interpro/entry/IPR000219", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR000306", "url": "https://www.ebi.ac.uk/interpro/entry/IPR000306", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR001849", "url": "https://www.ebi.ac.uk/interpro/entry/IPR001849", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR011011", "url": "https://www.ebi.ac.uk/interpro/entry/IPR011011", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR011993", "url": "https://www.ebi.ac.uk/interpro/entry/IPR011993", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR013083", "url": "https://www.ebi.ac.uk/interpro/entry/IPR013083", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR017455", "url": "https://www.ebi.ac.uk/interpro/entry/IPR017455", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR035899", "url": "https://www.ebi.ac.uk/interpro/entry/IPR035899", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR035941", "url": "https://www.ebi.ac.uk/interpro/entry/IPR035941", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR051092", "url": "https://www.ebi.ac.uk/interpro/entry/IPR051092", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "PTHR12673", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR12673", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR12673:SF14", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR12673:SF14", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00169", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00169", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF00621", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00621", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF01363", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF01363", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "XP_059745020", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_059745020", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0AAA9SV30", "url": "https://www.uniprot.org/uniprotkb/A0AAA9SV30", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0AAA9SV30-1", "url": "https://www.uniprot.org/uniprotkb/A0AAA9SV30-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0AAA9TVP8", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TVP8", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0AAA9TVP8-1", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TVP8-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0AAF6DMH8", "url": "https://www.uniprot.org/uniprotkb/A0AAF6DMH8", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0AAF6DMH8-1", "url": "https://www.uniprot.org/uniprotkb/A0AAF6DMH8-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MKPPASPSQRSENSALRMEPGRGSSTPPAPSATMEEPDAGPNNSSLEQPSTDPGKLPALPVGPGTHHGELASGSPGSQASAGDMSSVGEASSSKIPNRDSGIDSPSCSVVSEHFCEDSGEAGPGTIIKGPHPGTALGSKSPQEEADSDAGEGSSEEPDPENNPSKVDMDPAKCSEPQKLLHIAQELLHTEETYVKRLYLLDQVFCTGLTEAGIPSEVTTGIFSNISSIYRFHGQFLLPELQARITNEWDVNPRLGDILQKLAPFLKMYGEYVKNFDRAMELVSTWTQRSPVFKDTVQSIQKQELCGNLTLQHHMLEPVQRVPRYELLLKDYLKRLPEDAPDWKDAERSLELISTAANHSNAAIRKMEKMHKLLEVYERLGGEEDIVNPANELIKEGHIQKLSAKNGTTQDRHLFLFNSMILYCVPKLRLMGQKFSVREKMDISGLQVQDIVKSGAAHTFIITGKKRSLELQTRTEEEKKEWIQVIQATIEKHKQNSQTFKAFSGSFSQDENSPLTPEPPMMSPSSEVPAVPANSGGGVSGSEPRRGSSKTRRDKEKQGCSSCGETFNSITKRKHHCKLCGAVICGKCSEFKAENGRQSRVCKECFLTQPVAHLNLSLEEPLEPKQSTEKPVAAEPPPSLLCGPLQVSDGGTAWSKAWAAISESDSLELVLHLHEGSQDGQLLHAIPLSGCRVSVLDPAERLDARHVWQLQQAQQSLYLSAPSAELQQQWLEALSSAAHRHSSQASLGAPQPQAPAAP", "length": 757, "header": "tr|A0AAA9TVP8-1|A0AAA9TVP8_BOVIN Isoform 1 of FYVE, RhoGEF and PH domain containing 3 OS=Bos taurus OX=9913 GN=FGD3 PE=4 SV=1 CANONICAL=A0AAA9TVP8-1" }, "isoforms": [ { "isoform_ac": "A0AAA9SV30-1", "url": "https://www.uniprot.org/uniprotkb/A0AAA9SV30/entry", "sequence": { "sequence": "MEPGRGSSTPPAPSATMEEPDAGPNNSSLEQPSTDPGKLPALPVGPGTHHGELASGSPGSQASAGDMSSVGEASSSKIPNRDSGIDSPSCSVVSEHFCEDSGEAGPGTIIKGPHPGTALGSKSPQEEADSDAGEGSSEEPDPENNPSKVDMDPAKCSEPQKLLHIAQELLHTEETYVKRLYLLDQVFCTGLTEAGIPSEVTTGIFSNISSIYRFHGQFLLPELQARITNEWDVNPRLGDILQKLAPFLKMYGEYVKNFDRAMELVSTWTQRSPVFKDTVQSIQKQELCGNLTLQHHMLEPVQRVPRYELLLKDYLKRLPEDAPDWKDAERSLELISTAANHSNAAIRKMEKMHKLLEVYERLGGEEDIVNPANELIKEGHIQKLSAKNGTTQDRHLFLFNSMILYCVPKLRLMGQKFSVREKMDISGLQVQDIVKSGAAHTFIITGKKRSLELQTRTEEEKKEWIQVIQATIEKHKQNSQTFKAFSGSFSQDENSPLTPEPPMMSPSSEVPAVPANSGGGVSGSEPRRGSSKTRRDKEKQGCSSCGETFNSITKRKHHCKLCGAVICGKCSEFKAENGRQSRVCKECFLTQPVAHLNLSLEEPLEPKQSTEKPVAAEPPPSLLCGPLQVSDGGTAWSKAWAAISESDSLELVLHLHEGSQQDGQLLHAIPLSGCRVSVLDPAERLDARHVWQLQQAQQSLYLSAPSAELQQQWLEALSSAAHRHSSQASLGAPQPQAPAAP", "length": 741, "header": "tr|A0AAA9SV30-1|A0AAA9TVP8_BOVIN Computationally mapped isoform of FYVE, RhoGEF and PH domain containing 3 OS=Bos taurus OX=9913 GN=FGD3 PE=4 SV=1 CANONICAL=A0AAA9TVP8-1" }, "locus": { "chromosome": "8", "start_pos": 84419930, "end_pos": 84388690, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000107578.2", "url": "https://www.ensembl.org/id/ENSBTAT00000107578.2" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000087039.1", "url": "https://www.ensembl.org/id/ENSBTAP00000087039.1" } ] } }, { "isoform_ac": "A0AAA9TVP8-1", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TVP8/entry", "sequence": { "sequence": "MKPPASPSQRSENSALRMEPGRGSSTPPAPSATMEEPDAGPNNSSLEQPSTDPGKLPALPVGPGTHHGELASGSPGSQASAGDMSSVGEASSSKIPNRDSGIDSPSCSVVSEHFCEDSGEAGPGTIIKGPHPGTALGSKSPQEEADSDAGEGSSEEPDPENNPSKVDMDPAKCSEPQKLLHIAQELLHTEETYVKRLYLLDQVFCTGLTEAGIPSEVTTGIFSNISSIYRFHGQFLLPELQARITNEWDVNPRLGDILQKLAPFLKMYGEYVKNFDRAMELVSTWTQRSPVFKDTVQSIQKQELCGNLTLQHHMLEPVQRVPRYELLLKDYLKRLPEDAPDWKDAERSLELISTAANHSNAAIRKMEKMHKLLEVYERLGGEEDIVNPANELIKEGHIQKLSAKNGTTQDRHLFLFNSMILYCVPKLRLMGQKFSVREKMDISGLQVQDIVKSGAAHTFIITGKKRSLELQTRTEEEKKEWIQVIQATIEKHKQNSQTFKAFSGSFSQDENSPLTPEPPMMSPSSEVPAVPANSGGGVSGSEPRRGSSKTRRDKEKQGCSSCGETFNSITKRKHHCKLCGAVICGKCSEFKAENGRQSRVCKECFLTQPVAHLNLSLEEPLEPKQSTEKPVAAEPPPSLLCGPLQVSDGGTAWSKAWAAISESDSLELVLHLHEGSQDGQLLHAIPLSGCRVSVLDPAERLDARHVWQLQQAQQSLYLSAPSAELQQQWLEALSSAAHRHSSQASLGAPQPQAPAAP", "length": 757, "header": "tr|A0AAA9TVP8-1|A0AAA9TVP8_BOVIN Isoform 1 of FYVE, RhoGEF and PH domain containing 3 OS=Bos taurus OX=9913 GN=FGD3 PE=4 SV=1 CANONICAL=A0AAA9TVP8-1" }, "locus": { "chromosome": "8", "start_pos": 84419930, "end_pos": 84388021, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000100815.1", "url": "https://www.ensembl.org/id/ENSBTAT00000100815.1" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000101490.1", "url": "https://www.ensembl.org/id/ENSBTAP00000101490.1" } ] } }, { "isoform_ac": "A0AAF6DMH8-1", "url": "https://www.uniprot.org/uniprotkb/A0AAF6DMH8/entry", "sequence": { "sequence": "MEPGRGSSTPPAPSATMEEPDAGPNNSSLEQPSTDPGKLPALPVGPGTHHGELASGSPGSQASAGDMSSVGEASSSKIPNRDSGIDSPSCSVVSEHFCEDSGEAGPGTIIKGPHPGTALGSKSPQEEADSDAGEGSSEEPDPENNPSKVDMDPAKCSEPQKLLHIAQELLHTEETYVKRLYLLDQVFCTGLTEAGIPSEVTTGIFSNISSIYRFHGQFLLPELQARITNEWDVNPRLGDILQKLAPFLKMYGEYVKNFDRAMELVSTWTQRSPVFKDTVQSIQKQELCGNLTLQHHMLEPVQRVPRYELLLKDYLKRLPEDAPDWKDAERSLELISTAANHSNAAIRKMEKMHKLLEVYERLGGEEDIVNPANELIKEGHIQKLSAKNGTTQDRHLFLVQDIVKSGAAHTFIITGKKRSLELQTRTEEEKKEWIQVIQATIEKHKQNSQTFKAFSGSFSQDENSPLTPEPPMMSPSSEVPAVPANSGGGVSGSEPRRGSSKTRRDKEKQGCSSCGETFNSITKRKHHCKLCGAVICGKCSEFKAENGRQSRVCKECFLTQPVAHLNLSLEEPLEPKQSTEKPVAAEPPPSLLCGPLQVSDGGTAWSKAWAAISESDSLELVLHLHEGSQDGQLLHAIPLSGCRVSVLDPAERLDARHVWQLQQAQQSLYLSAPSAELQQQWLEALSSAAHRHSSQASLGAPQPQAPAAP", "length": 709, "header": "tr|A0AAF6DMH8-1|A0AAF6DMH8_BOVIN Computationally mapped isoform of FYVE, RhoGEF and PH domain containing 3 OS=Bos taurus OX=9913 GN=FGD3 PE=4 SV=1 CANONICAL=A0AAA9TVP8-1" }, "locus": { "chromosome": "8", "start_pos": 84419930, "end_pos": 84388690, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000009131.7", "url": "https://www.ensembl.org/id/ENSBTAT00000009131.7" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000009131.5", "url": "https://www.ensembl.org/id/ENSBTAP00000009131.5" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [], "orthologs": [], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 1, "go_terms": [ { "name": "cytoskeleton", "id": "GO:0005856", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005856", "evidence": [ { "database": "UniProtKB", "id": "A0AAA9TVP8", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TVP8" } ], "pmid": "" } ] }, { "name": "Molecular Function", "total": 2, "go_terms": [ { "name": "zinc ion binding", "id": "GO:0008270", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008270", "evidence": [ { "database": "UniProtKB", "id": "A0AAA9TVP8", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TVP8" } ], "pmid": "" }, { "name": "guanyl-nucleotide exchange factor activity", "id": "GO:0005085", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005085", "evidence": [ { "database": "UniProtKB", "id": "A0AAA9TVP8", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TVP8" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 224, "end_pos": 226, "annotation": "n_glycosylation_sequon" }, { "start_pos": 307, "end_pos": 309, "annotation": "n_glycosylation_sequon" }, { "start_pos": 357, "end_pos": 359, "annotation": "n_glycosylation_sequon" }, { "start_pos": 405, "end_pos": 407, "annotation": "n_glycosylation_sequon" }, { "start_pos": 42, "end_pos": 44, "annotation": "n_glycosylation_sequon" }, { "start_pos": 43, "end_pos": 45, "annotation": "n_glycosylation_sequon" }, { "start_pos": 614, "end_pos": 616, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A0AAA9TVP8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TVP8" }, { "id": "PS50010", "database": "PROSITE", "url": "https://prosite.expasy.org/PS50010" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "DH", "eco_id": "ECO_0000259", "start_pos": 178, "end_pos": 362, "start_aa": "Lys", "end_aa": "Ala", "glycosite_overlap": [] }, { "evidence": [ { "id": "A0AAA9TVP8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TVP8" }, { "id": "PS50178", "database": "PROSITE", "url": "https://prosite.expasy.org/PS50178" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "FYVE-type", "eco_id": "ECO_0000259", "start_pos": 553, "end_pos": 609, "start_aa": "Asp", "end_aa": "Pro", "glycosite_overlap": [] }, { "evidence": [ { "id": "A0AAA9TVP8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TVP8" }, { "id": "PS50003", "database": "PROSITE", "url": "https://prosite.expasy.org/PS50003" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "PH", "eco_id": "ECO_0000259", "start_pos": 391, "end_pos": 490, "start_aa": "Glu", "end_aa": "Glu", "glycosite_overlap": [] } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 224, "end_pos": 226 }, { "start_pos": 307, "end_pos": 309 }, { "start_pos": 357, "end_pos": 359 }, { "start_pos": 405, "end_pos": 407 }, { "start_pos": 42, "end_pos": 44 }, { "start_pos": 43, "end_pos": 45 }, { "start_pos": 614, "end_pos": 616 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ], "tool_support": { "graph_view": "yes" } }, { "uniprot_canonical_ac": "A0AAA9TSJ5-1", "uniprot_ac": "A0AAA9TSJ5", "uniprot_id": "A0AAA9TSJ5_BOVIN", "mass": { "chemical_mass": 29873.0, "monoisotopic_mass": 29873.0 }, "refseq": {}, "gene_names": [ { "name": "ALKBH6", "type": "recommended", "evidence": [ { "id": "A0AAA9TSJ5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TSJ5" } ] } ], "protein_names": [ { "name": "AlkB homolog 6", "type": "synonym", "evidence": [ { "id": "A0AAA9TSJ5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TSJ5/entry#names_and_taxonomy" } ] } ], "function": [ { "annotation": "Probable Fe(2+)/2-oxoglutarate-dependent dioxygenase involved in oxidative demethylation of nucleic acids. Binds nucleic acids with a preference for ssDNA or ssRNA to other types of DNAs. May play a role in nucleic acid damage repair.", "evidence": [ { "database": "UniProtKB", "id": "A0AAA9SX65", "url": "https://www.uniprot.org/uniprotkb/A0AAA9SX65#function" }, { "database": "UniProtKB", "id": "ARBA00093418", "url": "https://www.uniprot.org/uniprotkb/ARBA00093418#function" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Bos taurus", "taxid": 9913, "evidence": [ { "database": "UniProtKB", "id": "A0AAA9TSJ5", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TSJ5" } ], "common_name": "Bovine", "glygen_name": "Bovine", "reference_species": "Bos taurus [9913]" } ], "gene": [ { "name": "ALKBH6", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TSJ5", "locus": { "chromosome": "18", "start_pos": 46681222, "end_pos": 46687363, "strand": "+", "evidence": [ { "database": "Ensembl Gene", "id": "ENSBTAG00000019678", "url": "https://www.ensembl.org/id/ENSBTAG00000019678" } ] } } ], "crossref": [ { "id": "A0AAA9TSJ5", "url": "https://alphafold.ebi.ac.uk/entry/A0AAA9TSJ5", "database": "AlphaFoldDB", "categories": [] }, { "id": "ENSBTAG00000019678", "url": "https://bgee.org/?page=gene&gene_id=ENSBTAG00000019678", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "IPR005123", "url": "https://www.ebi.ac.uk/interpro/entry/IPR005123", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR027450", "url": "https://www.ebi.ac.uk/interpro/entry/IPR027450", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR032862", "url": "https://www.ebi.ac.uk/interpro/entry/IPR032862", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR037151", "url": "https://www.ebi.ac.uk/interpro/entry/IPR037151", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "F1N5I3", "url": "https://www.orthodb.org/?gene=F1N5I3", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR46030", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR46030", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR46030:SF1", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR46030:SF1", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF13532", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF13532", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "A0AAA9SX65", "url": "https://www.uniprot.org/uniprotkb/A0AAA9SX65", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0AAA9SX65-1", "url": "https://www.uniprot.org/uniprotkb/A0AAA9SX65-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0AAA9TSJ5", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TSJ5", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0AAA9TSJ5-1", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TSJ5-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "F1N5I3", "url": "https://www.uniprot.org/uniprotkb/F1N5I3", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "F1N5I3-1", "url": "https://www.uniprot.org/uniprotkb/F1N5I3-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MLEGSLVDGLTGYLELLSMEDQDARVPALEPFRVEQAPPVIYYIPDFISKEEEEYLLRQVFNAPKPKWTQLSGRKLQNWGGLPHPRGMVPERLPPWLQRYVDKVSDLSLFGGLPANHVLVNQYLPGEGIMPHEDGPLYYPTVSTISLGSHTMLDLYEPRQPEDDNPTEQPAGAPWHRLHAPPPWHRGSQRRRARGSLPAAQRRRLPLGAAGSPPGARHPRLADHPPSPPRAARWPPAQQVTLGPRTRSDSRARSRSGLLPPCDLGSLG", "length": 268, "header": "tr|A0AAA9TSJ5-1|A0AAA9TSJ5_BOVIN Isoform 1 of AlkB homolog 6 OS=Bos taurus OX=9913 GN=ALKBH6 PE=3 SV=1 CANONICAL=A0AAA9TSJ5-1" }, "isoforms": [ { "isoform_ac": "A0AAA9SX65-1", "url": "https://www.uniprot.org/uniprotkb/A0AAA9SX65/entry", "sequence": { "sequence": "MGLTGYLELLSMEDQDARVPALEPFRVEQAPPVIYYIPDFISKEEEEYLLRQVFNAPKPKWTQLSGRKLQNWGGLPHPRGMVPERLPPWLQRYVDKVSDLSLFGGLPANHVLVNQYLPGEGIMPHEDGPLYYPTVSTISLGSHTMLDLYEPRQPEDDNPTEQPRPPPRPATSLLLEPRSLLVLRGTAYTRLLHGIAAASVDALEAASLPPNAAACPSAQPGARLVRGTRVSLTIRRVPRVLRAGLLLSK", "length": 249, "header": "tr|A0AAA9SX65-1|A0AAA9TSJ5_BOVIN Computationally mapped isoform of AlkB homolog 6 OS=Bos taurus OX=9913 GN=ALKBH6 PE=3 SV=1 CANONICAL=A0AAA9TSJ5-1" }, "locus": { "chromosome": "18", "start_pos": 46686951, "end_pos": 46681672, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000101512.1", "url": "https://www.ensembl.org/id/ENSBTAT00000101512.1" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000089929.1", "url": "https://www.ensembl.org/id/ENSBTAP00000089929.1" } ] } }, { "isoform_ac": "A0AAA9TSJ5-1", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TSJ5/entry", "sequence": { "sequence": "MLEGSLVDGLTGYLELLSMEDQDARVPALEPFRVEQAPPVIYYIPDFISKEEEEYLLRQVFNAPKPKWTQLSGRKLQNWGGLPHPRGMVPERLPPWLQRYVDKVSDLSLFGGLPANHVLVNQYLPGEGIMPHEDGPLYYPTVSTISLGSHTMLDLYEPRQPEDDNPTEQPAGAPWHRLHAPPPWHRGSQRRRARGSLPAAQRRRLPLGAAGSPPGARHPRLADHPPSPPRAARWPPAQQVTLGPRTRSDSRARSRSGLLPPCDLGSLG", "length": 268, "header": "tr|A0AAA9TSJ5-1|A0AAA9TSJ5_BOVIN Isoform 1 of AlkB homolog 6 OS=Bos taurus OX=9913 GN=ALKBH6 PE=3 SV=1 CANONICAL=A0AAA9TSJ5-1" }, "locus": { "chromosome": "18", "start_pos": 46687224, "end_pos": 46681586, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000094285.1", "url": "https://www.ensembl.org/id/ENSBTAT00000094285.1" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000100010.1", "url": "https://www.ensembl.org/id/ENSBTAP00000100010.1" } ] } }, { "isoform_ac": "F1N5I3-1", "url": "https://www.uniprot.org/uniprotkb/F1N5I3/entry", "sequence": { "sequence": "MLEGSLVDGLTGYLELLSMEDQDARVPALEPFRVEQVFNAPKPKWTQLSGRKLQNWGGLPHPRGMVPERLPPWLQRYVDKVSDLSLFGGLPANHVLVNQYLPGEGIMPHEDGPLYYPTVSTISLGSHTMLDLYEPRQPEDDNPTEQPRPPPRPATSLLLEPRSLLVLRGTAYTRLLHGIAAASVDALEAASLPPNAAACPSAQPGARLVRGTRVSLTIRRVPRVLRAGLLLSK", "length": 233, "header": "tr|F1N5I3-1|F1N5I3_BOVIN Computationally mapped isoform of AlkB homolog 6 OS=Bos taurus OX=9913 GN=ALKBH6 PE=3 SV=4 CANONICAL=A0AAA9TSJ5-1" }, "locus": { "chromosome": "18", "start_pos": 46687224, "end_pos": 46681672, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000026225.7", "url": "https://www.ensembl.org/id/ENSBTAT00000026225.7" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000026225.7", "url": "https://www.ensembl.org/id/ENSBTAP00000026225.7" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [], "orthologs": [], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 2, "go_terms": [ { "name": "nucleus", "id": "GO:0005634", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005634", "evidence": [ { "database": "UniProtKB", "id": "A0AAA9TSJ5", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TSJ5" } ], "pmid": "" }, { "name": "cytoplasm", "id": "GO:0005737", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005737", "evidence": [ { "database": "UniProtKB", "id": "A0AAA9TSJ5", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TSJ5" } ], "pmid": "" } ] }, { "name": "Molecular Function", "total": 3, "go_terms": [ { "name": "metal ion binding", "id": "GO:0046872", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0046872", "evidence": [ { "database": "UniProtKB", "id": "A0AAA9TSJ5", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TSJ5" } ], "pmid": "" }, { "name": "dioxygenase activity", "id": "GO:0051213", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0051213", "evidence": [ { "database": "UniProtKB", "id": "A0AAA9TSJ5", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TSJ5" } ], "pmid": "" }, { "name": "2-oxoglutarate-dependent dioxygenase activity", "id": "GO:0016706", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016706", "evidence": [ { "database": "UniProtKB", "id": "A0AAA9TSJ5", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TSJ5" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A0AAA9TSJ5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TSJ5" }, { "id": "PS51471", "database": "PROSITE", "url": "https://prosite.expasy.org/PS51471" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "Fe2OG dioxygenase", "eco_id": "ECO_0000259", "start_pos": 114, "end_pos": 205, "start_aa": "Pro", "end_aa": "Leu", "glycosite_overlap": [] } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ], "tool_support": { "graph_view": "yes" } }, { "uniprot_canonical_ac": "A0AAA9TSQ4-1", "uniprot_ac": "A0AAA9TSQ4", "uniprot_id": "A0AAA9TSQ4_BOVIN", "mass": { "chemical_mass": 51033.0, "monoisotopic_mass": 51033.0 }, "refseq": {}, "gene_names": [ { "name": "CASP6", "type": "recommended", "evidence": [ { "id": "A0AAA9TSQ4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TSQ4" } ] } ], "protein_names": [ { "name": "Group XIIA secretory phospholipase A2", "type": "recommended", "evidence": [ { "id": "A0AAA9TSQ4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TSQ4/entry#names_and_taxonomy" } ] }, { "name": "Phosphatidylcholine 2-acylhydrolase 12A", "type": "synonym", "evidence": [ { "id": "A0AAA9TSQ4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TSQ4/entry#names_and_taxonomy" } ] } ], "function": [ { "annotation": "PA2 catalyzes the calcium-dependent hydrolysis of the 2-acyl groups in 3-sn-phosphoglycerides. Does not exhibit detectable activity toward sn-2-arachidonoyl- or linoleoyl-phosphatidylcholine or -phosphatidylethanolamine.", "evidence": [ { "database": "UniProtKB", "id": "A0AAA9TSQ4", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TSQ4#function" }, { "database": "UniProtKB", "id": "ARBA00055247", "url": "https://www.uniprot.org/uniprotkb/ARBA00055247#function" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Bos taurus", "taxid": 9913, "evidence": [ { "database": "UniProtKB", "id": "A0AAA9TSQ4", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TSQ4" } ], "common_name": "Bovine", "glygen_name": "Bovine", "reference_species": "Bos taurus [9913]" } ], "gene": [ { "name": "CASP6", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TSQ4", "locus": { "chromosome": "6", "start_pos": 15714981, "end_pos": 15675670, "strand": "-", "evidence": [ { "database": "Ensembl Gene", "id": "ENSBTAG00000012537", "url": "https://www.ensembl.org/id/ENSBTAG00000012537" } ] } } ], "crossref": [ { "id": "A0AAA9TSQ4", "url": "https://alphafold.ebi.ac.uk/entry/A0AAA9TSQ4", "database": "AlphaFoldDB", "categories": [] }, { "id": "cd00032", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd00032", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "IPR001309", "url": "https://www.ebi.ac.uk/interpro/entry/IPR001309", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR002138", "url": "https://www.ebi.ac.uk/interpro/entry/IPR002138", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR002398", "url": "https://www.ebi.ac.uk/interpro/entry/IPR002398", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR010711", "url": "https://www.ebi.ac.uk/interpro/entry/IPR010711", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR011600", "url": "https://www.ebi.ac.uk/interpro/entry/IPR011600", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR015917", "url": "https://www.ebi.ac.uk/interpro/entry/IPR015917", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR016129", "url": "https://www.ebi.ac.uk/interpro/entry/IPR016129", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR029030", "url": "https://www.ebi.ac.uk/interpro/entry/IPR029030", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR033113", "url": "https://www.ebi.ac.uk/interpro/entry/IPR033113", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR033139", "url": "https://www.ebi.ac.uk/interpro/entry/IPR033139", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR036444", "url": "https://www.ebi.ac.uk/interpro/entry/IPR036444", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "PTHR10454", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR10454", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR10454:SF206", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR10454:SF206", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR12824", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR12824", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR12824:SF7", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR12824:SF7", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00656", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00656", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF06951", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF06951", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "A0AAA9SXZ7", "url": "https://www.uniprot.org/uniprotkb/A0AAA9SXZ7", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0AAA9SXZ7-1", "url": "https://www.uniprot.org/uniprotkb/A0AAA9SXZ7-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0AAA9TSQ4", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TSQ4", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0AAA9TSQ4-1", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TSQ4-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0ABI0NNZ7", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NNZ7", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0ABI0NNZ7-1", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NNZ7-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0ABI0NYV5", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NYV5", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0ABI0NYV5-1", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NYV5-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MALLAVLLVLFLTAGGRCQEQAQTTDWRATLKTIRNGVHKIDMYLNAALDLLGGEDGLCQYKCSDGSKPFPRYGYKPSPPNGCGSPLFGVHLNIGIPSLTKCCNQHDRCYETCGKSKNDCDEAFQSCLSKICRDVQKTLGLAQHVQACETTVELLFDSVIHLGCKPYLDSQRAACEEQNMTEIDAFPRREIFDPTEKYKMDHKRRGIALIFNHERFFWHLTLPNRPGTSADRDNLRRRFSDLGFEVKCFDDLRAEELLLKIHEASTASHVDADCFLCVFLSHGEGNHIYAYDAKIEIQTLTGLFKGDKCQSLVGKPKIFIIQACRGSQHDVPVIPLDVVDHRTDTPDVNLTQVDAASVYTLPAGADFLMCYSVAEGYYSHRETVNGSWYIQDLCEMLGKFGSSLEFTELLTLVNRKVSQRRVDFCRDPNAIGKKQVPCFASMLTKKLHFSPKSK", "length": 454, "header": "tr|A0AAA9TSQ4-1|A0AAA9TSQ4_BOVIN Isoform 1 of Group XIIA secretory phospholipase A2 OS=Bos taurus OX=9913 GN=CASP6 PE=3 SV=1 CANONICAL=A0AAA9TSQ4-1" }, "isoforms": [ { "isoform_ac": "A0AAA9SXZ7-1", "url": "https://www.uniprot.org/uniprotkb/A0AAA9SXZ7/entry", "sequence": { "sequence": "MSSEPPPRRARGPGEEQNMTEIDAFPRREIFDPTEKYKMDHKRRGIALIFNHERFFWHLTLPNRPGTSADRDNLRRSINC", "length": 80, "header": "tr|A0AAA9SXZ7-1|A0AAA9TSQ4_BOVIN Computationally mapped isoform of Group XIIA secretory phospholipase A2 OS=Bos taurus OX=9913 GN=CASP6 PE=3 SV=1 CANONICAL=A0AAA9TSQ4-1" }, "locus": { "chromosome": "6", "start_pos": 15710332, "end_pos": 15694143, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000089627.1", "url": "https://www.ensembl.org/id/ENSBTAT00000089627.1" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000089116.1", "url": "https://www.ensembl.org/id/ENSBTAP00000089116.1" } ] } }, { "isoform_ac": "A0AAA9TSQ4-1", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TSQ4/entry", "sequence": { "sequence": "MALLAVLLVLFLTAGGRCQEQAQTTDWRATLKTIRNGVHKIDMYLNAALDLLGGEDGLCQYKCSDGSKPFPRYGYKPSPPNGCGSPLFGVHLNIGIPSLTKCCNQHDRCYETCGKSKNDCDEAFQSCLSKICRDVQKTLGLAQHVQACETTVELLFDSVIHLGCKPYLDSQRAACEEQNMTEIDAFPRREIFDPTEKYKMDHKRRGIALIFNHERFFWHLTLPNRPGTSADRDNLRRRFSDLGFEVKCFDDLRAEELLLKIHEASTASHVDADCFLCVFLSHGEGNHIYAYDAKIEIQTLTGLFKGDKCQSLVGKPKIFIIQACRGSQHDVPVIPLDVVDHRTDTPDVNLTQVDAASVYTLPAGADFLMCYSVAEGYYSHRETVNGSWYIQDLCEMLGKFGSSLEFTELLTLVNRKVSQRRVDFCRDPNAIGKKQVPCFASMLTKKLHFSPKSK", "length": 454, "header": "tr|A0AAA9TSQ4-1|A0AAA9TSQ4_BOVIN Isoform 1 of Group XIIA secretory phospholipase A2 OS=Bos taurus OX=9913 GN=CASP6 PE=3 SV=1 CANONICAL=A0AAA9TSQ4-1" }, "locus": { "chromosome": "6", "start_pos": 15714592, "end_pos": 15675764, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000131451.2", "url": "https://www.ensembl.org/id/ENSBTAT00000131451.2" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000101414.1", "url": "https://www.ensembl.org/id/ENSBTAP00000101414.1" } ] } }, { "isoform_ac": "A0ABI0NNZ7-1", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NNZ7/entry", "sequence": { "sequence": "MTEIDAFPRREIFDPTEKYKMDHKRRGIALIFNHERFFWHLTLPNRPGTSADRDNLRRRWFSDLGFEVKCFDDLRAEELLLKIHEASTASHVDADCFLCVFLSHGEGNHIYAYDAKIEIQTLTGLFKGDKCQSLVGKPKIFIIQACRGSQHDVPVIPLDVVDHRTDTPDVNLTQVDAASVYTLPAGADFLMCYSVAEGYYSHRETVNGSWYIQDLCEMLGKFGSSLEFTELLTLVNRKVSQRRVDFCRDPNAIGKKQVPCFASMLTKKLHFSPKSK", "length": 276, "header": "tr|A0ABI0NNZ7-1|A0ABI0NNZ7_BOVIN Computationally mapped isoform of Caspase-6 OS=Bos taurus OX=9913 GN=CASP6 PE=3 SV=1 CANONICAL=A0AAA9TSQ4-1" }, "locus": { "chromosome": "6", "start_pos": 15714592, "end_pos": 15707101, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000139588.1", "url": "https://www.ensembl.org/id/ENSBTAT00000139588.1" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000107195.1", "url": "https://www.ensembl.org/id/ENSBTAP00000107195.1" } ] } }, { "isoform_ac": "A0ABI0NYV5-1", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NYV5/entry", "sequence": { "sequence": "MGEEQNMTEIDAFPRREIFDPTEKYKMDHKRRGIALIFNHERFFWHLTLPNRPGTSADRDNLRRRFSDLGFEVKCFDDLRAEELLLKIHEASTASHVDADCFLCVFLSHGEGNHIYAYDAKIEIQTLTGLFKGDKCQSLVGKPKIFIIQACRGSQHDVPVIPLDVVDHRTDTPDVNLTQVDAASVYTLPAGADFLMCYSVAEGYYSHRETVNGSWYIQDLCEMLGKFGSSLEFTELLTLVNRKVSQRRVDFCRDPNAIGKKQVPCFASMLTKKLHFSPKSK", "length": 281, "header": "tr|A0ABI0NYV5-1|A0ABI0NYV5_BOVIN Computationally mapped isoform of Caspase-6 OS=Bos taurus OX=9913 GN=CASP6 PE=3 SV=1 CANONICAL=A0AAA9TSQ4-1" }, "locus": { "chromosome": "6", "start_pos": 15714592, "end_pos": 15691960, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000143207.1", "url": "https://www.ensembl.org/id/ENSBTAT00000143207.1" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000105555.1", "url": "https://www.ensembl.org/id/ENSBTAP00000105555.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [ "enzyme" ], "publication": [], "pathway": [], "orthologs": [], "go_annotation": { "categories": [ { "name": "Biological Process", "total": 5, "go_terms": [ { "name": "proteolysis", "id": "GO:0006508", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006508", "evidence": [ { "database": "UniProtKB", "id": "A0AAA9TSQ4", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TSQ4" } ], "pmid": "" }, { "name": "apoptotic process", "id": "GO:0006915", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006915", "evidence": [ { "database": "UniProtKB", "id": "A0AAA9TSQ4", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TSQ4" } ], "pmid": "" }, { "name": "lipid catabolic process", "id": "GO:0016042", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016042", "evidence": [ { "database": "UniProtKB", "id": "A0AAA9TSQ4", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TSQ4" } ], "pmid": "" }, { "name": "arachidonate secretion", "id": "GO:0050482", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0050482", "evidence": [ { "database": 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"https://www.ebi.ac.uk/QuickGO/term/GO:0004623", "evidence": [ { "database": "UniProtKB", "id": "A0AAA9TSQ4", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TSQ4" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 3, "go_terms": [ { "name": "extracellular region", "id": "GO:0005576", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005576", "evidence": [ { "database": "UniProtKB", "id": "A0AAA9TSQ4", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TSQ4" } ], "pmid": "" }, { "name": "cytoplasm", "id": "GO:0005737", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005737", "evidence": [ { "database": "UniProtKB", "id": "A0AAA9TSQ4", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TSQ4" } ], "pmid": "" }, { "name": "nucleus", "id": "GO:0005634", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005634", "evidence": [ { "database": "UniProtKB", "id": "A0AAA9TSQ4", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TSQ4" } ], "pmid": "" } ] } ] }, "pro_annotation": [], 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"publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ], "tool_support": { "graph_view": "yes" } }, { "uniprot_canonical_ac": "A0AAA9TWD1-1", "uniprot_ac": "A0AAA9TWD1", "uniprot_id": "A0AAA9TWD1_BOVIN", "mass": { "chemical_mass": 51910.0, "monoisotopic_mass": 51910.0 }, "refseq": {}, "gene_names": [ { "name": "PTPN20", "type": "recommended", "evidence": [ { "id": "A0AAA9TWD1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TWD1" } ] } ], "protein_names": [ { "name": "Tyrosine-protein phosphatase non-receptor type 20", "type": "recommended", "evidence": [ { "id": "A0AAA9TWD1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TWD1/entry#names_and_taxonomy" } ] }, { "name": "3.1.3.48", "type": "synonym", "evidence": [ { "id": "A0AAA9TWD1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TWD1/entry#names_and_taxonomy" } ] } ], "function": [ { "annotation": "Tyrosine-protein phosphatase targeted to sites of actin polymerization in response of varied extracellular stimuli. Has tyrosine phosphatase activity towards various tyrosyl phosphorylated substrates.", "evidence": [ { "database": "UniProtKB", "id": "A0AAA9TWD1", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TWD1#function" }, { "database": "UniProtKB", "id": "ARBA00058215", "url": "https://www.uniprot.org/uniprotkb/ARBA00058215#function" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Bos taurus", "taxid": 9913, "evidence": [ { "database": "UniProtKB", "id": "A0AAA9TWD1", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TWD1" } ], "common_name": "Bovine", "glygen_name": "Bovine", "reference_species": "Bos taurus [9913]" } ], "gene": [ { "name": "PTPN20", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TWD1", "locus": { "chromosome": "28", "start_pos": 42512086, "end_pos": 42576625, "strand": "+", "evidence": [ { "database": "Ensembl Gene", "id": "ENSBTAG00000056616", "url": "https://www.ensembl.org/id/ENSBTAG00000056616" } ] } } ], "crossref": [ { "id": "A0AAA9TWD1", "url": "https://alphafold.ebi.ac.uk/entry/A0AAA9TWD1", "database": "AlphaFoldDB", "categories": [] }, { "id": "IPR000242", "url": "https://www.ebi.ac.uk/interpro/entry/IPR000242", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR000387", "url": "https://www.ebi.ac.uk/interpro/entry/IPR000387", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR003595", "url": "https://www.ebi.ac.uk/interpro/entry/IPR003595", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR016130", "url": "https://www.ebi.ac.uk/interpro/entry/IPR016130", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR029021", "url": "https://www.ebi.ac.uk/interpro/entry/IPR029021", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR052074", "url": "https://www.ebi.ac.uk/interpro/entry/IPR052074", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "PTHR46900", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR46900", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR46900:SF4", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR46900:SF4", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00102", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00102", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "10684", "url": "https://www.rhea-db.org/rhea/10684", "database": "Rhea", "categories": [ "Enzyme and Pathway" ] }, { "id": "A0AAA9SYR8", "url": "https://www.uniprot.org/uniprotkb/A0AAA9SYR8", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0AAA9SYR8-1", "url": "https://www.uniprot.org/uniprotkb/A0AAA9SYR8-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0AAA9TMU2", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TMU2", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0AAA9TMU2-1", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TMU2-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0AAA9TWD1", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TWD1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0AAA9TWD1-1", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TWD1-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MSSPENATAASGEDHRGKDSDMKNLSVPLPVSPHDDLPSSSHDDLHSSSCEDLHYSSCHDDLHSSSQEMTPRPVNHKVFQNEVNSRKLKVFLRDFQHSDDFEDQFKDEAESENDGTLRKTSSFFLKQKSSSEDEELAGPSHPALQGMEIVSEKELAQLALVRPLIFNTQEESTIRDYFKILTKKVSEDEITQEFKALEVKNLPAVFHSGNELHNRDKNRYRDILPYDSTRVPLGENKDYINASYIKIANSREEYYYIATQGPLPTTTNDFWQMVWENNSNVIAMITKEKEGGVTKCHHYWPISMKKPLELNSCRIFLENYQILRYFIIRMFQVVKKSTGASHFVKHLQFTNWPDHGTPASAEGFIKYVRYVRKSHLTGPVVVHCSAGVGRTGVFLCVDVVFCAIEKNFSFDIMNIVSQMREQRHGMVQTKEQYMFCYKIVLEVLQKLWTVK", "length": 451, "header": "tr|A0AAA9TWD1-1|A0AAA9TWD1_BOVIN Isoform 1 of Tyrosine-protein phosphatase non-receptor type 20 OS=Bos taurus OX=9913 GN=PTPN20 PE=3 SV=1 CANONICAL=A0AAA9TWD1-1" }, "isoforms": [ { "isoform_ac": "A0AAA9SYR8-1", "url": "https://www.uniprot.org/uniprotkb/A0AAA9SYR8/entry", "sequence": { "sequence": "MSSPENATAASGEDHRGKDSDMKNLSVPLPVSPHDDLPSSSHDDLHSSSCEDLHYSSCHDDLHSSSQEMTPRPVNHKVFQNEVNSRKLKVFLRDFQHSDDFEDQFKDEAESENDGTLRKTSSFFLKQKSSSEDEELAGPSHPALQGMEIVSEKELAQLALVRPLIFNTQEESTIRDYFKILTKKVSEDEITQEFKTGASHFVKHLQFTNWPDHGTPASAEGFIKYVRYVRKSHLTGPVVVHCSAGVGRTGVFLCVDVVFCAIEKNFSFDIMNIVSQMREQRHGMVQTKEQYMFCYKIVLEVLQKLWTVK", "length": 309, "header": "tr|A0AAA9SYR8-1|A0AAA9TWD1_BOVIN Computationally mapped isoform of Tyrosine-protein phosphatase non-receptor type 20 OS=Bos taurus OX=9913 GN=PTPN20 PE=3 SV=1 CANONICAL=A0AAA9TWD1-1" }, "locus": { "chromosome": "28", "start_pos": 42566253, "end_pos": 42513090, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000104759.1", "url": "https://www.ensembl.org/id/ENSBTAT00000104759.1" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000089413.1", "url": "https://www.ensembl.org/id/ENSBTAP00000089413.1" } ] } }, { "isoform_ac": "A0AAA9TMU2-1", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TMU2/entry", "sequence": { "sequence": "MIDDSTRVPLGENKDYINASYIKIANSREEYYYIATQGPLPTTTNDFWQMVWENNSNVIAMITKEKEGGVTKCHHYWPISMKKPLELNSCRIFLENYQILRYFIIRMFQVVKKSTGASHFVKHLQFTNWPDHGTPASAEGFIKYVRYVRKSHLTGPVVVHCSAGVGRTGVFLCVDVVFCAIEKNFSFDIMNIVSQMREQRHGMVQTKEQYMFCYKIVLEVLQKLWTVK", "length": 228, "header": "tr|A0AAA9TMU2-1|A0AAA9TWD1_BOVIN Computationally mapped isoform of Tyrosine-protein phosphatase non-receptor type 20 OS=Bos taurus OX=9913 GN=PTPN20 PE=3 SV=1 CANONICAL=A0AAA9TWD1-1" }, "locus": { "chromosome": "28", "start_pos": 42576324, "end_pos": 42513090, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000095437.1", "url": "https://www.ensembl.org/id/ENSBTAT00000095437.1" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000099835.1", "url": "https://www.ensembl.org/id/ENSBTAP00000099835.1" } ] } }, { "isoform_ac": "A0AAA9TWD1-1", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TWD1/entry", "sequence": { "sequence": "MSSPENATAASGEDHRGKDSDMKNLSVPLPVSPHDDLPSSSHDDLHSSSCEDLHYSSCHDDLHSSSQEMTPRPVNHKVFQNEVNSRKLKVFLRDFQHSDDFEDQFKDEAESENDGTLRKTSSFFLKQKSSSEDEELAGPSHPALQGMEIVSEKELAQLALVRPLIFNTQEESTIRDYFKILTKKVSEDEITQEFKALEVKNLPAVFHSGNELHNRDKNRYRDILPYDSTRVPLGENKDYINASYIKIANSREEYYYIATQGPLPTTTNDFWQMVWENNSNVIAMITKEKEGGVTKCHHYWPISMKKPLELNSCRIFLENYQILRYFIIRMFQVVKKSTGASHFVKHLQFTNWPDHGTPASAEGFIKYVRYVRKSHLTGPVVVHCSAGVGRTGVFLCVDVVFCAIEKNFSFDIMNIVSQMREQRHGMVQTKEQYMFCYKIVLEVLQKLWTVK", "length": 451, "header": "tr|A0AAA9TWD1-1|A0AAA9TWD1_BOVIN Isoform 1 of Tyrosine-protein phosphatase non-receptor type 20 OS=Bos taurus OX=9913 GN=PTPN20 PE=3 SV=1 CANONICAL=A0AAA9TWD1-1" }, "locus": { "chromosome": "28", "start_pos": 42566253, "end_pos": 42513090, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000089191.1", "url": "https://www.ensembl.org/id/ENSBTAT00000089191.1" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000100927.1", "url": "https://www.ensembl.org/id/ENSBTAP00000100927.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [ "enzyme" ], "publication": [], "pathway": [], "orthologs": [], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 1, "go_terms": [ { "name": "nucleus", "id": "GO:0005634", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005634", "evidence": [ { "database": "UniProtKB", "id": "A0AAA9TWD1", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TWD1" } ], "pmid": "" } ] }, { "name": "Molecular Function", "total": 1, "go_terms": [ { "name": "protein tyrosine phosphatase activity", "id": "GO:0004725", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0004725", "evidence": [ { "database": "UniProtKB", "id": "A0AAA9TWD1", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TWD1" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 241, "end_pos": 243, "annotation": "n_glycosylation_sequon" }, { "start_pos": 24, "end_pos": 26, "annotation": "n_glycosylation_sequon" }, { "start_pos": 277, "end_pos": 279, "annotation": "n_glycosylation_sequon" }, { "start_pos": 407, "end_pos": 409, "annotation": "n_glycosylation_sequon" }, { "start_pos": 6, "end_pos": 8, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [ { "id": "10684", "name": "", "equation": "O-phospho-L-tyrosyl-[protein] + H2O = L-tyrosyl-[protein] + phosphate", "summary": "", "cellular_location": "", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [ "F1ME76-1", "F1MRH9-1", "A0AAF6DLF7-1", "A0AAA9S9Q3-1", "E1BFE2-1", "E1BL76-1", "G3MXS7-1", "A0A3Q1LUB1-1", "A0AAA9THG9-1", "F1N339-1", "F6RY99-1", "A0AAF6YUC8-1", "A0AAA9RTM1-1", "A0AAA9SMJ6-1", "A0A3Q1LZA9-1", "A7MBD1-1", "A5D7P0-1", "Q58DB6-1", "A0AAA9SEK4-1", "E1BDH9-1", "F1MGK4-1", "E1BIH4-1", "A0A3Q1M6K1-1", "E1BIU8-1", "A7MBJ4-1", "A6H730-1", "A0A3Q1MFX2-1", "A0AAA9U0H6-1", "A2VDT1-1", "E1BPU9-1", "P0C591-1", "P11064-1", "Q0IID7-1", "Q2KJ36-1", "Q2T9S4-1", "E1BPA0-1", "A0AAA9TAZ9-1", "Q5BIP9-1", "A0A3Q1M5K4-1", "F1MM08-1", "E1BJR7-1", "Q17QJ3-1", "Q17QM8-1", "F1MD22-1", "F1MI99-1", "F1MP34-1", "F1MGK5-1", "F1MEZ2-1", "F1MQM7-1", "E1BEZ8-1", "A0A3Q1M0B4-1", "A0AAA9S7W5-1", "A0A3Q1N8V6-1", "A0AAA9TFV5-1", "A0A3Q1MBB1-1", "F1MTZ3-1", "A0AAF6Z8C2-1", "F1MDF1-1", "A0AAA9T5N9-1", "E1BKT4-1", "A0A3Q1MH98-1", "F1N6L3-1", "F1MW70-1", "F1MXF2-1", "A0AAA9TWD1-1" ], "evidence": [ { "id": "10684", "database": "Rhea", "url": "https://www.rhea-db.org/rhea/10684" } ] } ], "reaction_participants": [], "reaction_enzymes": [ { "uniprot_ac": "A0A3Q1LUB1", "gene_name": "PTPRD", "activity": [ { "ec_number": "3.1.3.48", "activity": "O-phospho-L-tyrosyl-[protein] + H2O = L-tyrosyl-[protein] + phosphate.", "evidence": [ { "id": "A0A3Q1LUB1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1LUB1" } ] }, { "ec_number": "3.1.3.48", "activity": "", "evidence": [ { "id": "A0A3Q1LUB1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1LUB1" } ] } ] }, { "uniprot_ac": "A0A3Q1LZA9", "gene_name": "DUSP15", "activity": [ { "ec_number": "3.1.3.16", "activity": "O-phospho-L-threonyl-[protein] + H2O = L-threonyl-[protein] + phosphate.", "evidence": [ { "id": "A0A3Q1LZA9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1LZA9" } ] }, { "ec_number": "3.1.3.48", "activity": "O-phospho-L-tyrosyl-[protein] + H2O = L-tyrosyl-[protein] + phosphate.", "evidence": [ { "id": "A0A3Q1LZA9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1LZA9" } ] }, { "ec_number": "3.1.3.16", "activity": "", "evidence": [ { "id": "A0A3Q1LZA9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1LZA9" } ] }, { "ec_number": "3.1.3.48", "activity": "", "evidence": [ { "id": "A0A3Q1LZA9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1LZA9" } ] } ] }, { "uniprot_ac": "A0A3Q1M0B4", "gene_name": "PTPN12", "activity": [ { "ec_number": "3.1.3.48", "activity": "O-phospho-L-tyrosyl-[protein] + H2O = L-tyrosyl-[protein] + phosphate.", "evidence": [ { "id": "A0A3Q1M0B4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1M0B4" } ] }, { "ec_number": "3.1.3.48", "activity": "", "evidence": [ { "id": "A0A3Q1M0B4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1M0B4" } ] } ] }, { "uniprot_ac": "A0A3Q1M5K4", "gene_name": "EYA4", "activity": [ { "ec_number": "3.1.3.48", "activity": "O-phospho-L-tyrosyl-[protein] + H2O = L-tyrosyl-[protein] + phosphate.", "evidence": [ { "id": "A0A3Q1M5K4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1M5K4" } ] }, { "ec_number": "3.1.3.48", "activity": "", "evidence": [ { "id": "A0A3Q1M5K4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1M5K4" } ] } ] }, { "uniprot_ac": "A0A3Q1M6K1", "gene_name": "PTPRJ", "activity": [ { "ec_number": "3.1.3.48", "activity": "O-phospho-L-tyrosyl-[protein] + H2O = L-tyrosyl-[protein] + phosphate.", "evidence": [ { "id": "A0A3Q1M6K1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1M6K1" } ] }, { "ec_number": "3.1.3.48", "activity": "", "evidence": [ { "id": "A0A3Q1M6K1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1M6K1" } ] } ] }, { "uniprot_ac": "A0A3Q1MBB1", "gene_name": "TNS2", "activity": [ { "ec_number": "3.1.3.48", "activity": "O-phospho-L-tyrosyl-[protein] + H2O = L-tyrosyl-[protein] + phosphate.", "evidence": [ { "id": "A0A3Q1MBB1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1MBB1" } ] }, { "ec_number": "3.1.3.48", "activity": "", "evidence": [ { "id": "A0A3Q1MBB1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1MBB1" } ] } ] }, { "uniprot_ac": "A0A3Q1MFX2", "gene_name": "EYA1", "activity": [ { "ec_number": "3.1.3.48", "activity": "O-phospho-L-tyrosyl-[protein] + H2O = L-tyrosyl-[protein] + phosphate.", "evidence": [ { "id": "A0A3Q1MFX2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1MFX2" } ] }, { "ec_number": "3.1.3.48", "activity": "", "evidence": [ { "id": "A0A3Q1MFX2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1MFX2" } ] } ] }, { "uniprot_ac": "A0A3Q1MH98", "gene_name": "DUSP28", "activity": [ { "ec_number": "3.1.3.16", "activity": "O-phospho-L-threonyl-[protein] + H2O = L-threonyl-[protein] + phosphate.", "evidence": [ { "id": "A0A3Q1MH98", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1MH98" } ] }, { "ec_number": "3.1.3.48", "activity": "O-phospho-L-tyrosyl-[protein] + H2O = L-tyrosyl-[protein] + phosphate.", "evidence": [ { "id": "A0A3Q1MH98", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1MH98" } ] }, { "ec_number": "3.1.3.16", "activity": "", "evidence": [ { "id": "A0A3Q1MH98", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1MH98" } ] }, { "ec_number": "3.1.3.48", "activity": "", "evidence": [ { "id": "A0A3Q1MH98", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1MH98" } ] } ] }, { "uniprot_ac": "A0A3Q1N8V6", "gene_name": "LOC101903026", "activity": [ { "ec_number": "3.1.3.2", "activity": "a phosphate monoester + H2O = an alcohol + phosphate.", "evidence": [ { "id": "A0A3Q1N8V6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1N8V6" } ] }, { "ec_number": "3.1.3.48", "activity": "O-phospho-L-tyrosyl-[protein] + H2O = L-tyrosyl-[protein] + phosphate.", "evidence": [ { "id": "A0A3Q1N8V6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1N8V6" } ] }, { "ec_number": "3.1.3.48", "activity": "", "evidence": [ { "id": "A0A3Q1N8V6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1N8V6" } ] }, { "ec_number": "3.1.3.2", "activity": "", "evidence": [ { "id": "A0A3Q1N8V6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1N8V6" } ] } ] }, { "uniprot_ac": "A0AAA9RTM1", "gene_name": "DUSP22", "activity": [ { "ec_number": "3.1.3.16", "activity": "O-phospho-L-threonyl-[protein] + H2O = L-threonyl-[protein] + phosphate.", "evidence": [ { "id": "A0AAA9RTM1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9RTM1" } ] }, { "ec_number": "3.1.3.48", "activity": "O-phospho-L-tyrosyl-[protein] + H2O = L-tyrosyl-[protein] + phosphate.", "evidence": [ { "id": "A0AAA9RTM1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9RTM1" } ] }, { "ec_number": "3.1.3.16", "activity": "", "evidence": [ { "id": "A0AAA9RTM1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9RTM1" } ] }, { "ec_number": "3.1.3.48", "activity": "", "evidence": [ { "id": "A0AAA9RTM1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9RTM1" } ] } ] }, { "uniprot_ac": "A0AAA9S7W5", "gene_name": "PTPRV", "activity": [ { "ec_number": "3.1.3.48", "activity": "O-phospho-L-tyrosyl-[protein] + H2O = L-tyrosyl-[protein] + phosphate.", "evidence": [ { "id": "A0AAA9S7W5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9S7W5" } ] }, { "ec_number": "3.1.3.48", "activity": "", "evidence": [ { "id": "A0AAA9S7W5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9S7W5" } ] } ] }, { "uniprot_ac": "A0AAA9S9Q3", "gene_name": "PTPRC", "activity": [ { "ec_number": "3.1.3.48", "activity": "O-phospho-L-tyrosyl-[protein] + H2O = L-tyrosyl-[protein] + phosphate.", "evidence": [ { "id": "A0AAA9S9Q3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9S9Q3" } ] }, { "ec_number": "3.1.3.48", "activity": "", "evidence": [ { "id": "A0AAA9S9Q3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9S9Q3" } ] } ] }, { "uniprot_ac": "A0AAA9SEK4", "gene_name": "PTPRE", "activity": [ { "ec_number": "3.1.3.48", "activity": "O-phospho-L-tyrosyl-[protein] + H2O = L-tyrosyl-[protein] + phosphate.", "evidence": [ { "id": "A0AAA9SEK4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9SEK4" } ] }, { "ec_number": "3.1.3.48", "activity": "", "evidence": [ { "id": "A0AAA9SEK4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9SEK4" } ] } ] }, { "uniprot_ac": "A0AAA9SMJ6", "gene_name": "PTPRH", "activity": [ { "ec_number": "3.1.3.48", "activity": "O-phospho-L-tyrosyl-[protein] + H2O = L-tyrosyl-[protein] + phosphate.", "evidence": [ { "id": "A0AAA9SMJ6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9SMJ6" } ] }, { "ec_number": "3.1.3.48", "activity": "", "evidence": [ { "id": "A0AAA9SMJ6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9SMJ6" } ] } ] }, { "uniprot_ac": "A0AAA9T5N9", "gene_name": "", "activity": [ { "ec_number": "3.1.3.2", "activity": "a phosphate monoester + H2O = an alcohol + phosphate.", "evidence": [ { "id": "A0AAA9T5N9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9T5N9" } ] }, { "ec_number": "3.1.3.48", "activity": "O-phospho-L-tyrosyl-[protein] + H2O = L-tyrosyl-[protein] + phosphate.", "evidence": [ { "id": "A0AAA9T5N9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9T5N9" } ] }, { "ec_number": "3.1.3.2", "activity": "", "evidence": [ { "id": "A0AAA9T5N9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9T5N9" } ] }, { "ec_number": "3.1.3.48", "activity": "", "evidence": [ { "id": "A0AAA9T5N9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9T5N9" } ] } ] }, { "uniprot_ac": "A0AAA9TAZ9", "gene_name": "PTPN2", "activity": [ { "ec_number": "3.1.3.48", "activity": "O-phospho-L-tyrosyl-[protein] + H2O = L-tyrosyl-[protein] + phosphate.", "evidence": [ { "id": "A0AAA9TAZ9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TAZ9" } ] }, { "ec_number": "3.1.3.48", "activity": "", "evidence": [ { "id": "A0AAA9TAZ9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TAZ9" } ] } ] }, { "uniprot_ac": "A0AAA9TFV5", "gene_name": "PTPN1", "activity": [ { "ec_number": "3.1.3.48", "activity": "O-phospho-L-tyrosyl-[protein] + H2O = L-tyrosyl-[protein] + phosphate.", "evidence": [ { "id": "A0AAA9TFV5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TFV5" } ] }, { "ec_number": "3.1.3.48", "activity": "", "evidence": [ { "id": "A0AAA9TFV5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TFV5" } ] } ] }, { "uniprot_ac": "A0AAA9THG9", "gene_name": "PTPRK", "activity": [ { "ec_number": "3.1.3.48", "activity": "O-phospho-L-tyrosyl-[protein] + H2O = L-tyrosyl-[protein] + phosphate.", "evidence": [ { "id": "A0AAA9THG9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9THG9" } ] }, { "ec_number": "3.1.3.48", "activity": "", "evidence": [ { "id": "A0AAA9THG9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9THG9" } ] } ] }, { "uniprot_ac": "A0AAA9TWD1", "gene_name": "PTPN20", "activity": [ { "ec_number": "3.1.3.48", "activity": "O-phospho-L-tyrosyl-[protein] + H2O = L-tyrosyl-[protein] + phosphate.", "evidence": [ { "id": "A0AAA9TWD1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TWD1" } ] }, { "ec_number": "3.1.3.48", "activity": "", "evidence": [ { "id": "A0AAA9TWD1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TWD1" } ] } ] }, { "uniprot_ac": "A0AAA9U0H6", "gene_name": "PTEN", "activity": [ { "ec_number": "3.1.3.67", "activity": "a 1,2-diacyl-sn-glycero-3-phospho-(1D-myo-inositol-3,4,5-trisphosphate) + H2O = a 1,2-diacyl-sn-glycero-3-phospho-(1D-myo-inositol-4,5-bisphosphate) + phosphate.", "evidence": [ { "id": "A0AAA9U0H6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9U0H6" } ] }, { "ec_number": "3.1.3.16", "activity": "O-phospho-L-threonyl-[protein] + H2O = L-threonyl-[protein] + phosphate.", "evidence": [ { "id": "A0AAA9U0H6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9U0H6" } ] }, { "ec_number": "3.1.3.48", "activity": "O-phospho-L-tyrosyl-[protein] + H2O = L-tyrosyl-[protein] + phosphate.", "evidence": [ { "id": "A0AAA9U0H6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9U0H6" } ] }, { "ec_number": "3.1.3.48", "activity": "", "evidence": [ { "id": "A0AAA9U0H6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9U0H6" } ] }, { "ec_number": "3.1.3.67", "activity": "", "evidence": [ { "id": "A0AAA9U0H6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9U0H6" } ] }, { "ec_number": "3.1.3.16", "activity": "", "evidence": [ { "id": "A0AAA9U0H6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9U0H6" } ] } ] }, { "uniprot_ac": "A0AAF6DLF7", "gene_name": "DUSP7", "activity": [ { "ec_number": "3.1.3.16", "activity": "O-phospho-L-threonyl-[protein] + H2O = L-threonyl-[protein] + phosphate.", "evidence": [ { "id": "A0AAF6DLF7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAF6DLF7" } ] }, { "ec_number": "3.1.3.48", "activity": "O-phospho-L-tyrosyl-[protein] + H2O = L-tyrosyl-[protein] + phosphate.", "evidence": [ { "id": "A0AAF6DLF7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAF6DLF7" } ] }, { "ec_number": "3.1.3.48", "activity": "", "evidence": [ { "id": "A0AAF6DLF7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAF6DLF7" } ] }, { "ec_number": "3.1.3.16", "activity": "", "evidence": [ { "id": "A0AAF6DLF7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAF6DLF7" } ] } ] }, { "uniprot_ac": "A0AAF6YUC8", "gene_name": "PGP", "activity": [ { "ec_number": "3.1.3.21", "activity": "sn-glycerol 1-phosphate + H2O = glycerol + phosphate.", "evidence": [ { "id": "A0AAF6YUC8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAF6YUC8" } ] }, { "ec_number": "3.1.3.48", "activity": "O-phospho-L-tyrosyl-[protein] + H2O = L-tyrosyl-[protein] + phosphate.", "evidence": [ { "id": "A0AAF6YUC8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAF6YUC8" } ] }, { "ec_number": "3.1.3.21", "activity": "", "evidence": [ { "id": "A0AAF6YUC8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAF6YUC8" } ] }, { "ec_number": "3.1.3.48", "activity": "", "evidence": [ { "id": "A0AAF6YUC8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAF6YUC8" } ] } ] }, { "uniprot_ac": "A0AAF6Z8C2", "gene_name": "ACP1", "activity": [ { "ec_number": "3.1.3.2", "activity": "a phosphate monoester + H2O = an alcohol + phosphate.", "evidence": [ { "id": "A0AAF6Z8C2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAF6Z8C2" } ] }, { "ec_number": "3.1.3.48", "activity": "O-phospho-L-tyrosyl-[protein] + H2O = L-tyrosyl-[protein] + phosphate.", "evidence": [ { "id": "A0AAF6Z8C2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAF6Z8C2" } ] }, { "ec_number": "3.1.3.48", "activity": "", "evidence": [ { "id": "A0AAF6Z8C2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAF6Z8C2" } ] }, { "ec_number": "3.1.3.2", "activity": "", "evidence": [ { "id": "A0AAF6Z8C2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAF6Z8C2" } ] } ] }, { "uniprot_ac": "A2VDT1", "gene_name": "PTP4A3", "activity": [ { "ec_number": "3.1.3.48", "activity": "O-phospho-L-tyrosyl-[protein] + H2O = L-tyrosyl-[protein] + phosphate.", "evidence": [ { "id": "A2VDT1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A2VDT1" } ] }, { "ec_number": "3.1.3.48", "activity": "", "evidence": [ { "id": "A2VDT1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A2VDT1" } ] } ] }, { "uniprot_ac": "A5D7P0", "gene_name": "CDC25C", "activity": [ { "ec_number": "3.1.3.48", "activity": "O-phospho-L-tyrosyl-[protein] + H2O = L-tyrosyl-[protein] + phosphate.", "evidence": [ { "id": "A5D7P0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A5D7P0" } ] }, { "ec_number": "3.1.3.48", "activity": "", "evidence": [ { "id": "A5D7P0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A5D7P0" } ] } ] }, { "uniprot_ac": "A6H730", "gene_name": "ACP3", "activity": [ { "ec_number": "3.1.3.5", "activity": "a ribonucleoside 5'-phosphate + H2O = a ribonucleoside + phosphate.", "evidence": [ { "id": "A6H730", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A6H730" } ] }, { "ec_number": "3.1.3.2", "activity": "a phosphate monoester + H2O = an alcohol + phosphate.", "evidence": [ { "id": "A6H730", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A6H730" } ] }, { "ec_number": "3.1.3.48", "activity": "O-phospho-L-tyrosyl-[protein] + H2O = L-tyrosyl-[protein] + phosphate.", "evidence": [ { "id": "A6H730", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A6H730" } ] }, { "ec_number": "3.1.3.2", "activity": "", "evidence": [ { "id": "A6H730", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A6H730" } ] } ] }, { "uniprot_ac": "A7MBD1", "gene_name": "CDC25A", "activity": [ { "ec_number": "3.1.3.48", "activity": "O-phospho-L-tyrosyl-[protein] + H2O = L-tyrosyl-[protein] + phosphate.", "evidence": [ { "id": "A7MBD1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A7MBD1" } ] }, { "ec_number": "3.1.3.48", "activity": "", "evidence": [ { "id": "A7MBD1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A7MBD1" } ] } ] }, { "uniprot_ac": "A7MBJ4", "gene_name": "PTPRF", "activity": [ { "ec_number": "3.1.3.48", "activity": "O-phospho-L-tyrosyl-[protein] + H2O = L-tyrosyl-[protein] + phosphate.", "evidence": [ { "id": "A7MBJ4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A7MBJ4" } ] }, { "ec_number": "3.1.3.48", "activity": "", "evidence": [ { "id": "A7MBJ4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A7MBJ4" } ] } ] }, { "uniprot_ac": "E1BDH9", "gene_name": "PTPRT", "activity": [ { "ec_number": "3.1.3.48", "activity": "O-phospho-L-tyrosyl-[protein] + H2O = L-tyrosyl-[protein] + phosphate.", "evidence": [ { "id": "E1BDH9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BDH9" } ] }, { "ec_number": "3.1.3.48", "activity": "", "evidence": [ { "id": "E1BDH9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BDH9" } ] } ] }, { "uniprot_ac": "E1BEZ8", "gene_name": "PTPN14", "activity": [ { "ec_number": "3.1.3.48", "activity": "O-phospho-L-tyrosyl-[protein] + H2O = L-tyrosyl-[protein] + phosphate.", "evidence": [ { "id": "E1BEZ8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BEZ8" } ] }, { "ec_number": "3.1.3.48", "activity": "", "evidence": [ { "id": "E1BEZ8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BEZ8" } ] } ] }, { "uniprot_ac": "E1BFE2", "gene_name": "PTPRB", "activity": [ { "ec_number": "3.1.3.48", "activity": "O-phospho-L-tyrosyl-[protein] + H2O = L-tyrosyl-[protein] + phosphate.", "evidence": [ { "id": "E1BFE2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BFE2" } ] }, { "ec_number": "3.1.3.48", "activity": "", "evidence": [ { "id": "E1BFE2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BFE2" } ] } ] }, { "uniprot_ac": "E1BIH4", "gene_name": "PTPN3", "activity": [ { "ec_number": "3.1.3.48", "activity": "O-phospho-L-tyrosyl-[protein] + H2O = L-tyrosyl-[protein] + phosphate.", "evidence": [ { "id": "E1BIH4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BIH4" } ] }, { "ec_number": "3.1.3.48", "activity": "", "evidence": [ { "id": "E1BIH4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BIH4" } ] } ] }, { "uniprot_ac": "E1BIU8", "gene_name": "PTPRS", "activity": [ { "ec_number": "3.1.3.48", "activity": "O-phospho-L-tyrosyl-[protein] + H2O = L-tyrosyl-[protein] + phosphate.", "evidence": [ { "id": "E1BIU8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BIU8" } ] }, { "ec_number": "3.1.3.48", "activity": "", "evidence": [ { "id": "E1BIU8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BIU8" } ] } ] }, { "uniprot_ac": "E1BJR7", "gene_name": "PTPN4", "activity": [ { "ec_number": "3.1.3.48", "activity": "O-phospho-L-tyrosyl-[protein] + H2O = L-tyrosyl-[protein] + phosphate.", "evidence": [ { "id": "E1BJR7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BJR7" } ] }, { "ec_number": "3.1.3.48", "activity": "", "evidence": [ { "id": "E1BJR7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BJR7" } ] } ] }, { "uniprot_ac": "E1BKT4", "gene_name": "PTPN13", "activity": [ { "ec_number": "3.1.3.48", "activity": "O-phospho-L-tyrosyl-[protein] + H2O = L-tyrosyl-[protein] + phosphate.", "evidence": [ { "id": "E1BKT4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BKT4" } ] }, { "ec_number": "3.1.3.48", "activity": "", "evidence": [ { "id": "E1BKT4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BKT4" } ] } ] }, { "uniprot_ac": "E1BL76", "gene_name": "CDC25B", "activity": [ { "ec_number": "3.1.3.48", "activity": "O-phospho-L-tyrosyl-[protein] + H2O = L-tyrosyl-[protein] + phosphate.", "evidence": [ { "id": "E1BL76", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BL76" } ] }, { "ec_number": "3.1.3.48", "activity": "", "evidence": [ { "id": "E1BL76", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BL76" } ] } ] }, { "uniprot_ac": "E1BPA0", "gene_name": "PTPRA", "activity": [ { "ec_number": "3.1.3.48", "activity": "O-phospho-L-tyrosyl-[protein] + H2O = L-tyrosyl-[protein] + phosphate.", "evidence": [ { "id": "E1BPA0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BPA0" } ] }, { "ec_number": "3.1.3.48", "activity": "", "evidence": [ { "id": "E1BPA0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BPA0" } ] } ] }, { "uniprot_ac": "E1BPU9", "gene_name": "PTPRM", "activity": [ { "ec_number": "3.1.3.48", "activity": "O-phospho-L-tyrosyl-[protein] + H2O = L-tyrosyl-[protein] + phosphate.", "evidence": [ { "id": "E1BPU9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BPU9" } ] }, { "ec_number": "3.1.3.48", "activity": "", "evidence": [ { "id": "E1BPU9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BPU9" } ] } ] }, { "uniprot_ac": "F1MD22", "gene_name": "PTPRU", "activity": [ { "ec_number": "3.1.3.48", "activity": "O-phospho-L-tyrosyl-[protein] + H2O = L-tyrosyl-[protein] + phosphate.", "evidence": [ { "id": "F1MD22", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MD22" } ] }, { "ec_number": "3.1.3.48", "activity": "", "evidence": [ { "id": "F1MD22", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MD22" } ] } ] }, { "uniprot_ac": "F1MDF1", "gene_name": "PTPN18", "activity": [ { "ec_number": "3.1.3.48", "activity": "O-phospho-L-tyrosyl-[protein] + H2O = L-tyrosyl-[protein] + phosphate.", "evidence": [ { "id": "F1MDF1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MDF1" } ] }, { "ec_number": "3.1.3.48", "activity": "", "evidence": [ { "id": "F1MDF1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MDF1" } ] } ] }, { "uniprot_ac": "F1ME76", "gene_name": "DUSP13B", "activity": [ { "ec_number": "3.1.3.16", "activity": "O-phospho-L-threonyl-[protein] + H2O = L-threonyl-[protein] + phosphate.", "evidence": [ { "id": "F1ME76", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1ME76" } ] }, { "ec_number": "3.1.3.48", "activity": "O-phospho-L-tyrosyl-[protein] + H2O = L-tyrosyl-[protein] + phosphate.", "evidence": [ { "id": "F1ME76", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1ME76" } ] }, { "ec_number": "3.1.3.16", "activity": "", "evidence": [ { "id": "F1ME76", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1ME76" } ] }, { "ec_number": "3.1.3.48", "activity": "", "evidence": [ { "id": "F1ME76", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1ME76" } ] } ] }, { "uniprot_ac": "F1MEZ2", "gene_name": "DUSP9", "activity": [ { "ec_number": "3.1.3.16", "activity": "O-phospho-L-threonyl-[protein] + H2O = L-threonyl-[protein] + phosphate.", "evidence": [ { "id": "F1MEZ2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MEZ2" } ] }, { "ec_number": "3.1.3.48", "activity": "O-phospho-L-tyrosyl-[protein] + H2O = L-tyrosyl-[protein] + phosphate.", "evidence": [ { "id": "F1MEZ2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MEZ2" } ] }, { "ec_number": "3.1.3.48", "activity": "", "evidence": [ { "id": "F1MEZ2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MEZ2" } ] }, { "ec_number": "3.1.3.16", "activity": "", "evidence": [ { "id": "F1MEZ2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MEZ2" } ] } ] }, { "uniprot_ac": "F1MGK4", "gene_name": "EYA3", "activity": [ { "ec_number": "3.1.3.48", "activity": "O-phospho-L-tyrosyl-[protein] + H2O = L-tyrosyl-[protein] + phosphate.", "evidence": [ { "id": "F1MGK4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MGK4" } ] }, { "ec_number": "3.1.3.48", "activity": "", "evidence": [ { "id": "F1MGK4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MGK4" } ] } ] }, { "uniprot_ac": "F1MGK5", "gene_name": "PTPRZ1", "activity": [ { "ec_number": "3.1.3.48", "activity": "O-phospho-L-tyrosyl-[protein] + H2O = L-tyrosyl-[protein] + phosphate.", "evidence": [ { "id": "F1MGK5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MGK5" } ] }, { "ec_number": "3.1.3.48", "activity": "", "evidence": [ { "id": "F1MGK5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MGK5" } ] } ] }, { "uniprot_ac": "F1MI99", "gene_name": "DUSP1", "activity": [ { "ec_number": "3.1.3.16", "activity": "O-phospho-L-threonyl-[protein] + H2O = L-threonyl-[protein] + phosphate.", "evidence": [ { "id": "F1MI99", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MI99" } ] }, { "ec_number": "3.1.3.48", "activity": "O-phospho-L-tyrosyl-[protein] + H2O = L-tyrosyl-[protein] + phosphate.", "evidence": [ { "id": "F1MI99", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MI99" } ] }, { "ec_number": "3.1.3.48", "activity": "", "evidence": [ { "id": "F1MI99", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MI99" } ] }, { "ec_number": "3.1.3.16", "activity": "", "evidence": [ { "id": "F1MI99", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MI99" } ] } ] }, { "uniprot_ac": "F1MM08", "gene_name": "DUSP4", "activity": [ { "ec_number": "3.1.3.16", "activity": "O-phospho-L-threonyl-[protein] + H2O = L-threonyl-[protein] + phosphate.", "evidence": [ { "id": "F1MM08", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MM08" } ] }, { "ec_number": "3.1.3.48", "activity": "O-phospho-L-tyrosyl-[protein] + H2O = L-tyrosyl-[protein] + phosphate.", "evidence": [ { "id": "F1MM08", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MM08" } ] }, { "ec_number": "3.1.3.48", "activity": "", "evidence": [ { "id": "F1MM08", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MM08" } ] }, { "ec_number": "3.1.3.16", "activity": "", "evidence": [ { "id": "F1MM08", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MM08" } ] } ] }, { "uniprot_ac": "F1MP34", "gene_name": "DUSP2", "activity": [ { "ec_number": "3.1.3.16", "activity": "O-phospho-L-threonyl-[protein] + H2O = L-threonyl-[protein] + phosphate.", "evidence": [ { "id": "F1MP34", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MP34" } ] }, { "ec_number": "3.1.3.48", "activity": "O-phospho-L-tyrosyl-[protein] + H2O = L-tyrosyl-[protein] + phosphate.", "evidence": [ { "id": "F1MP34", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MP34" } ] }, { "ec_number": "3.1.3.48", "activity": "", "evidence": [ { "id": "F1MP34", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MP34" } ] }, { "ec_number": "3.1.3.16", "activity": "", "evidence": [ { "id": "F1MP34", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MP34" } ] } ] }, { "uniprot_ac": "F1MQM7", "gene_name": "DUSP5", "activity": [ { "ec_number": "3.1.3.16", "activity": "O-phospho-L-threonyl-[protein] + H2O = L-threonyl-[protein] + phosphate.", "evidence": [ { "id": "F1MQM7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MQM7" } ] }, { "ec_number": "3.1.3.48", "activity": "O-phospho-L-tyrosyl-[protein] + H2O = L-tyrosyl-[protein] + phosphate.", "evidence": [ { "id": "F1MQM7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MQM7" } ] }, { "ec_number": "3.1.3.16", "activity": "", "evidence": [ { "id": "F1MQM7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MQM7" } ] }, { "ec_number": "3.1.3.48", "activity": "", "evidence": [ { "id": "F1MQM7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MQM7" } ] } ] }, { "uniprot_ac": "F1MRH9", "gene_name": "PTPN21", "activity": [ { "ec_number": "3.1.3.48", "activity": "O-phospho-L-tyrosyl-[protein] + H2O = L-tyrosyl-[protein] + phosphate.", "evidence": [ { "id": "F1MRH9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MRH9" } ] }, { "ec_number": "3.1.3.48", "activity": "", "evidence": [ { "id": "F1MRH9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MRH9" } ] } ] }, { "uniprot_ac": "F1MTZ3", "gene_name": "UBASH3B", "activity": [ { "ec_number": "3.1.3.48", "activity": "O-phospho-L-tyrosyl-[protein] + H2O = L-tyrosyl-[protein] + phosphate.", "evidence": [ { "id": "F1MTZ3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MTZ3" } ] }, { "ec_number": "3.1.3.48", "activity": "", "evidence": [ { "id": "F1MTZ3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MTZ3" } ] } ] }, { "uniprot_ac": "F1MW70", "gene_name": "DUSP12", "activity": [ { "ec_number": "3.1.3.16", "activity": "O-phospho-L-threonyl-[protein] + H2O = L-threonyl-[protein] + phosphate.", "evidence": [ { "id": "F1MW70", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MW70" } ] }, { "ec_number": "3.1.3.48", "activity": "O-phospho-L-tyrosyl-[protein] + H2O = L-tyrosyl-[protein] + phosphate.", "evidence": [ { "id": "F1MW70", "database": 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"https://www.ncbi.nlm.nih.gov/protein/XP_002692674" } ] } ], "protein_names": [ { "name": "Family with sequence similarity 91 member A1", "type": "synonym", "evidence": [ { "id": "A0AAA9TVP9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TVP9/entry#names_and_taxonomy" } ] }, { "name": "protein FAM91A1 isoform X1", "type": "synonym", "evidence": [ { "id": "XP_002692674", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_002692674" } ] } ], "function": [], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Bos taurus", "taxid": 9913, "evidence": [ { "database": "UniProtKB", "id": "A0AAA9TVP9", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TVP9" } ], "common_name": "Bovine", "glygen_name": "Bovine", "reference_species": "Bos taurus [9913]" } ], "gene": [ { "name": "FAM91A1", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TVP9", "locus": { "chromosome": "14", "start_pos": 16071525, "end_pos": 16112800, "strand": "+", "evidence": [ { "database": "Ensembl Gene", "id": "ENSBTAG00000005025", "url": "https://www.ensembl.org/id/ENSBTAG00000005025" } ] } } ], "crossref": [ { "id": "A0AAA9TVP9", "url": "https://alphafold.ebi.ac.uk/entry/A0AAA9TVP9", "database": "AlphaFoldDB", "categories": [] }, { "id": "ENSBTAG00000005025", "url": "https://bgee.org/?page=gene&gene_id=ENSBTAG00000005025", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "507013", "url": "https://www.ncbi.nlm.nih.gov/gene/507013", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR028091", "url": "https://www.ebi.ac.uk/interpro/entry/IPR028091", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR028097", "url": "https://www.ebi.ac.uk/interpro/entry/IPR028097", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR039199", "url": "https://www.ebi.ac.uk/interpro/entry/IPR039199", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "bta:507013", "url": "https://www.genome.jp/dbget-bin/www_bget?bta:507013", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "HYESFPF", "url": "https://omabrowser.org/oma/group/HYESFPF/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "F1MQF4", "url": "https://www.orthodb.org/?gene=F1MQF4", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR28441", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR28441", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR28441:SF2", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR28441:SF2", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF14647", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF14647", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF14648", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF14648", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "R-BTA-9013407", "url": "https://www.reactome.org/PathwayBrowser/#R-BTA-9013407", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "XP_002692674", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_002692674", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0AAA9SYY5", "url": "https://www.uniprot.org/uniprotkb/A0AAA9SYY5", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0AAA9SYY5-1", "url": "https://www.uniprot.org/uniprotkb/A0AAA9SYY5-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0AAA9TVP9", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TVP9", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0AAA9TVP9-1", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TVP9-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "F1MQF4", "url": "https://www.uniprot.org/uniprotkb/F1MQF4", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "F1MQF4-1", "url": "https://www.uniprot.org/uniprotkb/F1MQF4-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MNIDVEFHIRHNYPWSKLPANVRQSLGNSQREYEKQVVLYSIRNQLRYRNNLVKHVKKDERKYYEELLKYSRDHLMLYPYHLSDIMVKGLRITPFSYYTGIMEDIMNSEKSYDSLPNFTAADCLRLLGIGRNQYIDLMNQCRSSKKFFRRKTARDLLPVKPVEIAIEAWWVVQAAYITEDDIKICTLPEKCAIDKIIDAGPQLSGSLDYNVVHSLYNKGFVYLDVPISDDSCIAVPPLEGFVMNRVQGDYFETLLYKIFVSIDEHTNVAELANVLEIDLSLVKNAVSMYCRLGFAHKKGQVINLDQLHSSWKNVPSVNRLKSTLDPQKMLLSWDGGESRSPVQEASSATDTDTNSQEDPADTASINSLNLSTGYTKRIAFLFDSTLTAFLMMGNLSPNLKSHAVTMFEVGKLSDESLDSFLIELEKVQSTGEGEAQRYFDHALTLRNTILFLRHNKDLVAQTAQPDQPSYGFPLDLLRCESLLGLDPATCSRVLNKNYTLLVSMAPLTNEIRPVSSCTPQHIGPAIPEVSSVWFKLYIYHITRQGPPSLLLSKGTRLRKLPDIFQGYDRLLITSWGHDPGVVPTSNVLTMLNDALTHSAVLIQGHGLHGIGETVHIPFPFDETELQGEFTRVNMGVHKALQTLRNKVDLQHFCGYVTMLNASSQLANRKLSDASDERGEPDLASGSDVNGSTESFEMVIEEAALDSAAKQNSVATAEADWVPLELCFGIPLFSSELNQKVCRKIATHGLCRKESLQNLLHSSRKLSLQVLNFVHSFQEGASTLDVHTEASFPSLLSQSSCADMGVPLPAKNLVFKDGILTEWSGRSPSSLLIANLHLQ", "length": 838, "header": "tr|A0AAA9TVP9-1|A0AAA9TVP9_BOVIN Isoform 1 of Family with sequence similarity 91 member A1 OS=Bos taurus OX=9913 GN=FAM91A1 PE=3 SV=1 CANONICAL=A0AAA9TVP9-1" }, "isoforms": [ { "isoform_ac": "A0AAA9SYY5-1", "url": "https://www.uniprot.org/uniprotkb/A0AAA9SYY5/entry", "sequence": { "sequence": "MNIDVEFHIRHNYPWSKLPANVRQSLGNSQREYEKQVVLYSIRNQLRYRNNLVKHVKKDERKYYEELLKYSRDHLMLYPYHLSDIMVKGLRITPFSYYTGIMEDIMNSEKSYDSLPNFTAADCLRLLGIGRNQYIDLMNQCRSSKKFFRRKTARDLLPVKPVEIAIEAWWVVQAAYITEDDIKICTLPEKCAIDKIIDAGPQLSGSLDYNVVHSLYNKGFVYLDVPISDDSCIAVPPLEGFVMNRVQGDYFETLLYKIFVSIDEHTNVAELANVLEIDLSLVKNAVSMYCRLGFAHKKGQVINLDQLHSSWKNVPSVNRLKSTLDPQKMLLSWDGGESRSPVQEASSATDTDTNSQEDPGYTKRIAFLFDSTLTAFLMMGNLSPNLKSHAVTMFEVGKLSDESLDSFLIELEKVQSTGEGEAQRYFDHALTLRNTILFLRHNKDLVAQTAQPDQPSYGFPLDLLRCESLLGLDPATCSRVLNKNYTLLVSMAPLTNEIRPVSSCTPQHIGPAIPEVSSVWFKLYIYHITRQGPPSLLLSKGTRLRKLPDIFQGYDRLLITSWGHDPGVVPTSNVLTMLNDALTHSAVLIQGHGLHGIGETVHIPFPFDETELQGEFTRVNMGVHKALQTLRNKVDLQHFCGYVTMLNASSQLANRKLSDASDERGEPDLASGSDVNGSTESFEMVIEEAALDSAAKQNSVATAEADWVPLELCFGIPLFSSELNQKVCRKIATHGLCRKESLQNLLHSSRKLSLQVLNFVHSFQEGASTLDVHTEASFPSLLSQSSCADMGVPLPAKNLVFKDGILTEWSGRSPSSLLIANLHLQ", "length": 825, "header": "tr|A0AAA9SYY5-1|A0AAA9TVP9_BOVIN Computationally mapped isoform of Family with sequence similarity 91 member A1 OS=Bos taurus OX=9913 GN=FAM91A1 PE=3 SV=1 CANONICAL=A0AAA9TVP9-1" }, "locus": { "chromosome": "14", "start_pos": 16112544, "end_pos": 16074871, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000104912.1", "url": "https://www.ensembl.org/id/ENSBTAT00000104912.1" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000090595.1", "url": "https://www.ensembl.org/id/ENSBTAP00000090595.1" } ] } }, { "isoform_ac": "A0AAA9TVP9-1", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TVP9/entry", "sequence": { "sequence": "MNIDVEFHIRHNYPWSKLPANVRQSLGNSQREYEKQVVLYSIRNQLRYRNNLVKHVKKDERKYYEELLKYSRDHLMLYPYHLSDIMVKGLRITPFSYYTGIMEDIMNSEKSYDSLPNFTAADCLRLLGIGRNQYIDLMNQCRSSKKFFRRKTARDLLPVKPVEIAIEAWWVVQAAYITEDDIKICTLPEKCAIDKIIDAGPQLSGSLDYNVVHSLYNKGFVYLDVPISDDSCIAVPPLEGFVMNRVQGDYFETLLYKIFVSIDEHTNVAELANVLEIDLSLVKNAVSMYCRLGFAHKKGQVINLDQLHSSWKNVPSVNRLKSTLDPQKMLLSWDGGESRSPVQEASSATDTDTNSQEDPADTASINSLNLSTGYTKRIAFLFDSTLTAFLMMGNLSPNLKSHAVTMFEVGKLSDESLDSFLIELEKVQSTGEGEAQRYFDHALTLRNTILFLRHNKDLVAQTAQPDQPSYGFPLDLLRCESLLGLDPATCSRVLNKNYTLLVSMAPLTNEIRPVSSCTPQHIGPAIPEVSSVWFKLYIYHITRQGPPSLLLSKGTRLRKLPDIFQGYDRLLITSWGHDPGVVPTSNVLTMLNDALTHSAVLIQGHGLHGIGETVHIPFPFDETELQGEFTRVNMGVHKALQTLRNKVDLQHFCGYVTMLNASSQLANRKLSDASDERGEPDLASGSDVNGSTESFEMVIEEAALDSAAKQNSVATAEADWVPLELCFGIPLFSSELNQKVCRKIATHGLCRKESLQNLLHSSRKLSLQVLNFVHSFQEGASTLDVHTEASFPSLLSQSSCADMGVPLPAKNLVFKDGILTEWSGRSPSSLLIANLHLQ", "length": 838, "header": "tr|A0AAA9TVP9-1|A0AAA9TVP9_BOVIN Isoform 1 of Family with sequence similarity 91 member A1 OS=Bos taurus OX=9913 GN=FAM91A1 PE=3 SV=1 CANONICAL=A0AAA9TVP9-1" }, "locus": { "chromosome": "14", "start_pos": 16112544, "end_pos": 16074871, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000123854.1", "url": "https://www.ensembl.org/id/ENSBTAT00000123854.1" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000101233.1", "url": "https://www.ensembl.org/id/ENSBTAP00000101233.1" } ] } }, { "isoform_ac": "F1MQF4-1", "url": "https://www.uniprot.org/uniprotkb/F1MQF4/entry", "sequence": { "sequence": "MNIDVEFHIRHNYPWSKLPANVRQSLGNSQREYEKQVVLYSIRNQLRYRNNLVKHVKKDERKYYEELLKYSRDHLMLYPYHLSDIMVKGLRITPFSYYTGIMEDIMNSEKSYDSLPNFTAADCLRLLGIGRNQYIDLMNQCRSSKKFFRRKTARDLLPVKPVEIAIEAWWVVQAAYITEDDIKICTLPEKCAIDKIIDAGPQLSGSLDYNVVHSLYNKGFVYLDVPISDDSCIAVPPLEGFVMNRVQGDYFETLLYKIFVSIDEHTNVAELANVLEIDLSLVKNAVSMYCRLGFAHKKGQVINLDQLHSSWKNVPSVNRLKSTLDPQKMLLSWDGGESRSPVQEASSATDTDTNSQEDPADTASINSLNLSTGYTKRIAFLFDSTLTAFLMMGNLSPNLKSHAVTMFEVGKLSDESLDSFLIELEKVQSTGEGEAQRYFDHALTLRNTILFLRHNKDLVAQTAQPDQPSYGFPLDLLRCESLLGLDPATCSRVLNKNYTLLVSMAPLTNEIRPVSSCTPQHIGPAIPEVSSVWFKLYIYHITRQGPPSLLLSKGTRLRKLPDIFQGYDRLLITSWGHDPGVVPTSNVLTMLNDALTHSAVLIQGHGLHGIGETVHIPFPFDETELQGEFTRVNMGVHKALQTLRNKVDLQHFCGYVTMLNASSQLANRKLSDASDERGEPDLASGSDVNGSTESFEMVIEEAALDSAAKQNSVATAEADWVPLELCFGIPLFSSELNQKVCRKIATHGLCRKESLQNLLHSSRKLSLQVLNFVHSFQDRVQGTMVHFFSRHCLRLLQSVDSFSVFPDLEAVKSTSWFFGGLALTVGSSGVLSDWRL", "length": 836, "header": "tr|F1MQF4-1|F1MQF4_BOVIN Computationally mapped isoform of Family with sequence similarity 91 member A1 OS=Bos taurus OX=9913 GN=FAM91A1 PE=3 SV=4 CANONICAL=A0AAA9TVP9-1" }, "locus": { "chromosome": "14", "start_pos": 16112544, "end_pos": 16071649, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000006615.6", "url": "https://www.ensembl.org/id/ENSBTAT00000006615.6" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000006615.6", "url": "https://www.ensembl.org/id/ENSBTAP00000006615.6" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [ { "id": "bta:507013", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?bta:507013", "resource": "KEGG Pathway" }, { "id": "R-BTA-9013407", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-BTA-9013407", "resource": "Reactome", "description": "RHOH GTPase cycle" } ], "orthologs": [ { "uniprot_canonical_ac": "A0A8V0XT61-1", "protein_name": "Family with sequence similarity 91 member A1", "gene_name": "FAM91A1", "tax_id": 9031, "organism": "Gallus gallus", "sequence": { "sequence": "MNIDVEFHIRHNYLWARLPASVKQALGNSQREYERQVVLYSIRNQLRYRNNLVKHVKKDERKYYEDLLKYSRDHLMLYPYHLSDIMVKGLRVTPFSYYTGIMEDIMNSEKSYDSLPNFTAADCLRLLGIGRNQYIDLMNQCRSSKKFFRRKTARDLLPVKPVEITIEAWWVVQSGYITEDDIKICTTSEKSAIDKIIDSGPQLAGSLDFNVVHSLYNKGFIYLDVPISDDSCIAVPPLEGFVMNRVQGDYFETLLYKIFVSIDEHTNVAELANVLEIDLSLVKNAVSMYCRLGFAHKKGQVINLDNLHPSWKNVPSVNRLKSTLDPQKMLLSWDSGENRSPVQEAGSSATDTDTNSQDDPAETASVSSLNLSSGHTKRIAFLFDSTLTAFLMMGNLSPNLKSHAVTMFEVGKLSDESLDSFLVELEKVQSTGEGEAQRYFDHALTLRNTILFLRHNKDLGAQAVQPDQPTNGFPLDLLRCESLLGLDPATCSRVLNKNYILLVSMAPLTNEIRPISSCTPQHIGPAIPEVSSVWFKLYIYHITGQGPPSLLLSKGTRLRKLPDIFQGYDRLLITSWGHDPGVVPTSNVLTMLNDALTHSAVLIQGHGMHGMGETVHIPFPFDEAEQQGDFSRVNMGIHSALKVLRNKVDLQHFCGYVTMLNPTSRQASRKLSDASDGRGDADLASGSDVNGSTESFEMVIEETSMDSAIKQNLEVPTSELEWVPLELCFGIPLFSSELNQKVCRKIATHGLCRKESLQKLLHSSRKLSLQVLNFVHSFQEGTSTLDQLHDAGCSSSLLQPTSADMGVPLPAKNLMFKEGVLSEWNGRSPSSVFISTTPKEQVK", "length": 843 }, "evidence": [ { "id": "A0AAA9TVP9", "url": "https://omabrowser.org/oma/group/A0AAA9TVP9/", "database": "OMA" } ], "glygen_name": "Chicken", "common_name": "Chicken" }, { "uniprot_canonical_ac": "F4HYA7-1", "protein_name": "FAM91 carboxy-terminus protein", "gene_name": "", "tax_id": 3702, "organism": "Arabidopsis thaliana", "sequence": { "sequence": "MQHTPVTIEDQLISKAVREECQWENLPKRLQSILGSKDEWHRRVTAHCIKKRLLWNTCFACKVCKEGEYYEDMMRYLRKNLALFPYHLAEYVCRVMRISPFRYYCDMIFEVMRNEQPYDSIPNFSAADAFRLTGIGRNEFIDIMNKCRSKKIMWKLNKSIAKDFLPTLPVDFPIDPWWGVCLVNFTIEEFKKLSEDEMATIDKICKEEANAYFLFDPEVIKGLYQRGLVYFDVPVYQDDRFKVSKLEGFISNREQSYEDPIEELLYAVFVVSNENSTVAELASTLQADVTQLQAAASFVCRLGWAVKLIDPSSVLHDKIGSPRAILSDDEDASRASISSTYRSADGEEAQHGDNLGTESSGSRSSHVRVAFIVDANITSYLMMGSVSPGLKSHAVTLYEAGKLGHTSIPDLCQDLSTLEGAKFEGELQEFANHAFSLRCVLECLISGGVATDAIVDTMGSGTLSNDEAVTLLADVNLPDNSGDSLTSQIIEASMVSDAPQEVPLSTEHVPESTKHEAASSTPSVDTTALTETFSSNLNLQNEGKPIPVEGPDTGKGNKKRKKYRVDILRCESLASLTPATLDRLFSRDYDIVVSMIPLPLTTVLPGPSGPVHFGPPSHSSMTQWMKLVLYSTVGIGPLSVILMKGQCLRMLPAPLAGCEKAIIWSWDGSSVGGLGNKFEGNLVKGGILLHCLNCLLKCSAVLVQPLSKHDLDSSGRIVTLDIPLPLKNSDGSIPHFGDELGLPLEENTKLNSLLTKLANNMELKTVGYIRLLKLFKAKDSLKHFSPDNDEKYEWVPLTVEFGFPLFSPKLCNNICKRIVSSQLLQADSLMEQHDAMQCIRKRLKDICALYQATGPAAKLLYQKEQAKEPTRTNKLMNYASGRWNPLVDPSSPISGATSEFQRLKLANRQRCRTEVLSFDGSILRSYTLAPVYEAATRSIDENAPLSTTKSDSDEADSREVILPGLNLLYDGSELHPFDIGACLQARQPVALIAEAAAASASLAPK", "length": 1005 }, "evidence": [ { "id": "A0AAA9TVP9", "url": "https://omabrowser.org/oma/group/A0AAA9TVP9/", "database": "OMA" } ], "glygen_name": "Arabidopsis", "common_name": "Mouse-ear cress" }, { "uniprot_canonical_ac": "Q3UVG3-1", "protein_name": "Protein FAM91A1", "gene_name": "Fam91a1", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MNIDVEFHIRHNYPWSKLPTNVKQSLGNSQREYEKQVVLYSIRNQLRYRNNLVKHVKKDERKYYEELLKYSRDHLMLYPYHLSDIMVKGLRITPFSYYAGIMEDIMNSEKSYDSLPNFTAADCLRLLGIGRNQYIDLMNQCRSSKKFFRRKTARDLLPMKPVEIAIEAWWVVQAGYITEDDIKICTFPEKGAIDKIIDSGPQLSGSLDYNVVHSLYNKGFIYLDVPISDDSCIAVPPLEGFVMNRVQGDYFETLLYKIFVSIDEHTNVAELANVLEIDLSLVKNAVSMYCRLGFAHKKGQVINLDQLHSSWKNVPSVNRLKSTLDPQKMLLSWDGGESRSPVQEASSATDTDTNSQEDPADTASVSSLSLSTGYTKRIAFLFDSTLTAFLMMGNLSPNLKSHAVTMFEVGKLSDESLDSFLIELEKVQSTGEGEAQRYFDHALTLRNTILFLRHNKDLVAQTSQPDQPNYGFPLDLLRCESLLGLDPATCSRVLNKNYTLLVSMAPLTNEIRPVSSCTPQHIGPAIPEVSSVWFKLYIYHVTGQGPPSLLLSKGTRLRKLPDIFQGYDRLLITSWGHDPGVVPASNVLTMLNDALTHSAVLIQGHGLHGVGETVHIPFPFDEAELQGEFTRASMGVHKALQILRSRVDLQHFCGYVTMLNASSQLASRKLSEASDERGEPDLASSSDVNGSTESFEMVIEEASTDLATKPNSGATAEADWVPLELCFGIPLFSSELNRKVCQKIATHGLCRKESLQSLLHSSRKLSLQVLNFVHSFQEGAATLDLHAEPGFSSVLSQSPCADMGVPLPAKNLMFKDGVLSEWSGRSPSSLLIASLHL", "length": 837 }, "evidence": [ { "id": "A0AAA9TVP9", "url": "https://omabrowser.org/oma/group/A0AAA9TVP9/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q658Y4-1", "protein_name": "Protein FAM91A1", "gene_name": "FAM91A1", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MNIDVEFHIRHNYPWNKLPANVRQSLGNSQREYEKQVVLYSIRNQLRYRNNLVKHVKKDERRYYEELLKYSRDHLMLYPYHLSDIMVKGLRITPFSYYTGIMEDIMNSEKSYDSLPNFTAADCLRLLGIGRNQYIDLMNQCRSSKKFFRRKTARDLLPIKPVEIAIEAWWVVQAGYITEDDIKICTLPEKCAVDKIIDSGPQLSGSLDYNVVHSLYNKGFIYLDVPISDDSCIAVPPLEGFVMNRVQGDYFETLLYKIFVSIDEHTNVAELANVLEIDLSLVKNAVSMYCRLGFAHKKGQVINLDQLHSSWKNVPSVNRLKSTLDPQKMLLSWDGGESRSPVQEASSATDTDTNSQEDPADTASVSSLSLSTGHTKRIAFLFDSTLTAFLMMGNLSPNLKSHAVTMFEVGKLSDESLDSFLIELEKVQSTGEGEAQRYFDHALTLRNTILFLRHNKDLVAQTAQPDQPNYGFPLDLLRCESLLGLDPATCSRVLNKNYTLLVSMAPLTNEIRPVSSCTPQHIGPAIPEVSSVWFKLYIYHVTGQGPPSLLLSKGTRLRKLPDIFQSYDRLLITSWGHDPGVVPTSNVLTMLNDALTHSAVLIQGHGLHGIGETVHVPFPFDETELQGEFTRVNMGVHKALQILRNRVDLQHLCGYVTMLNASSQLADRKLSDASDERGEPDLASGSDVNGSTESFEMVIEEATIDSATKQTSGATTEADWVPLELCFGIPLFSSELNRKVCRKIAAHGLCRKESLQNLLHSSRKLSLQVLNFVHSFQEGASILDIHTEPSFSSLLSQSSCADMGVPLPAKNLIFKDGVLSEWSGRSPSSLLIANLHLQ", "length": 838 }, "evidence": [ { "id": "A0AAA9TVP9", "url": "https://omabrowser.org/oma/group/A0AAA9TVP9/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "Q6TEP1-1", "protein_name": "Protein FAM91A1", "gene_name": "fam91a1", "tax_id": 7955, "organism": "Danio rerio", "sequence": { "sequence": "MNTDVEFHIRQNYPWNKLPANVKQSLGNSQREYDKQVLLYSIRNQLRFRNNLVRHVKKDERKYYEELLKYSREHLMLYPYHLSDIMVKGLRVTPFSYYISIMEDIMNCEKSYDSLPNFTAADCLRLLGIGRNQYIDLMNQCRSSKKFFRRKSARDLLPAKPVEITVEPWWVVQTGYITEDDIRICSVAEKAAIDKMIDSGPQLAGSMEYNVVLSLYNRGYIYLDVPISDDSCISVPPLEGFVMNRVQGDYFETLLYKIFVSIDEQTNVSELANVLEIDLGLVKNAVSMYCRLGFAIKKGQVISPDQLHPSWKSAPSVNRLKGTMDPQKMLLSWEGGSPVMEAGSSATDTDTTSLEDQDTASVSSLSIPAAPTKRIAFLFDSTLTAFLMMGNLSPNLKSHAVTMFEVGKLSDETLDSFLMELEKVESTAEGEAQRYFDHALTLRNTILFLRYNKDLTPDQGPDVPNIGLPLDLLRCESLLGLDPATCSRVLNKNYKLLVSMAPLSNEIRPISSCTPQHIGPAIPEVSSIWFKLYLYSVTGQGPPSLLLSKGSRLRKLPDIFQAYDRLLITSWGHDPGVVPSSNVLTMLNDALTHSAVLIQGHGMHGHGETVHVPFPFDEEDLKGEFSYSNMCAHKALKILRDKVDLEHQCGYITMLNHNNRHRRRASDADGDAELCGVLDANGSNESFELVTEENNGDGGKKQGTEASSSEDEWVPLELCFGMPLFSSELNRKVCQRIVSHKLCSKDSLQELLHSSRKLALKVLSFVQSFQDGKQPADPDSGVSGPLSQPPAESGVPLPAINLLFKDGELKEWSGRAPPSLHISAPQRDQPT", "length": 831 }, "evidence": [ { "id": "A0AAA9TVP9", "url": "https://omabrowser.org/oma/group/A0AAA9TVP9/", "database": "OMA" } ], "glygen_name": "Zebrafish", "common_name": "Zebrafish" }, { "uniprot_canonical_ac": "Q8T158-1", "protein_name": "Protein FAM91 homolog", "gene_name": "fam91", "tax_id": 44689, "organism": "Dictyostelium discoideum", "sequence": { "sequence": "MDQSSEKELEKYINNRVQWDSLPSHAKSILDQSHVKYKQYCLKYSIKHQLRWDTNLISSFVTDERLYYQEIVRLSVANLVLYPYHIQDKLVPMLNVTPFKYYLIMMIETMTNSKSYDEIPNFTAVDCIRVLGIGRNQFIDLMNKFRSKGFLFKKKKDVIRGLLPTRSLEKNIEYWWILRYGYPNQDEERQGSLPASELEVLDDLKRSNGINGKQAGIYCRESVISLISKGLVYIDVPIQNQDTISVPPLEGFVMNRVLGDYFENLLYKIFVSIDERTTIQKLSEVLQINVELVKQACSLYCRLGFAKKKNLEPLLPQTPSPSSEGDTHSKWHHSWITYYQENETIIPQPILNNNNNNSNTIDNSNNNNNNNTNITSSSSSNTAINNSSQSSTLENNDNIVEGVVDESFNNGNEEQKRIGFVFDSSITAFLMMGNLGYGLKNHAVTMFERGKLSNEALADFLQELDKIDVEEFVDSEAKLYATNAISLRDTIRHLKNKYRIDDSNSSNSNSSSGGGSGNLQGLDLISCERMNQLDETTRIRVLKKNYSVLISMAPLSIDYCPVISSVPPNFGPAVYEVHSFWFRIYLYSMVGKGPNSILLPKGTRLKRIPTIFKDCEKILVCPIDHDPTTVNLSQLLPSVNETLLSSPVLLSAYTFIKYDTQPKLSKLMSHSRSNSIVSSSKDNQLLYHIPFPLDDLSADNGSPKKYTNIITNNTTTTTTTTTTTNTTNLNNNTIISEDQYNSDNIHTHPILYKIQSTFNLKNSFGYITLLKKETHILLNNNNNNNNKNNINNNKNNNNNNNNNNNNNNNNNNNNNNNNNNNNSITHQKVFEYLPLNVYYGIPIFDDKLNREVCAKIDKFNLLSKENLNRHSMDSRNLSLNLFNFISSTCPPIHPDLDSIDATKINSNLPSVQNIPFPTQIITFVNGNLDL", "length": 930 }, "evidence": [ { "id": "A0AAA9TVP9", "url": "https://omabrowser.org/oma/group/A0AAA9TVP9/", "database": "OMA" } ], "glygen_name": "Cellular slime mold", "common_name": "Social amoeba" }, { "uniprot_canonical_ac": "Q9XZ12-1", "protein_name": "Protein FAM91A1", "gene_name": "Dmel\\CG7600", "tax_id": 7227, "organism": "Drosophila melanogaster", "sequence": { "sequence": "MTEQEDLATSGGGNATTGSGTNCQNQLQQCVRGNVTWELLPVHLRSVLHNNQRDYEKFVFNYSLKNQLRFRGNLAAKVFRREQRYYELLIQKSINGLGAFPYHLADIVTKGLRVTPFNYYLDVLGQLLQSDKSYDTLPNFTAADCLRVLGIGRNEYLALISDMKTHTPRSLIFGSRPNPLDFLPRFPVRIHIEPWWRLDIGYVLEADIRYLSPAERGLLDDLIDFGAQPAGKCDHDVVHSLYRKGLIYLDVPISGEDRISIPPLRNFVMNRVSGDYFENLLYKIFVSADEHMTIAELAQMLQLELDSVKQAISFICRLGFAHRKEDLVNQTNHSSWEGYNQQQTPDTPQITPLNYNLHTSSSFEFDQSPKSPKTPKEREKDKDKDSSSIGYLSSDGNTSDFSFANLNTTPQERVNNSDEQELSSELEQEDMCAPKQAAPSAAISAAVLPKSGKRVGFLFDSTLTAFLMMGNLSPGLKNHAVTMFEVGKLCEESLDSFLAELEQVSLLDAEGEGDVSRYFAHAVILRSTICSLRHLLPGGLDLLRLECLEGLDQQTRDRVLEKKYKFIIAASPLTASLSHTFSIPYFGQFLRSSDVAPMWSKLFYNHITGYGPPSLLLCRGTVLKTLPRLFLGYGKLLVNILHSDAYVLNSENFRSLNSQLKNGCVLLQGYGIRTAGALHYESFPFQAADTRQAKWAAHRAVHKLSSLLDLRQQCGYITFLNTGVPDLGCEDYELQVRLKPAQRQKRTSIAAPSKPNHVPTNEVTSFQLKSPDENHFAATPEHGPANEFTAPDCSQVLASELAKCSSRADLVSQSSVEIEEISPSVVQEEDATEEWTLLDVNFGVPLFDVDTNTRICEQLVQGLCSDANLEALPAAASQAQVLFLDFVQQCLYFEDDPARQSVQAARPLPHPRINLAFENGHVCHWNGR", "length": 928 }, "evidence": [ { "id": "A0AAA9TVP9", "url": "https://omabrowser.org/oma/group/A0AAA9TVP9/", "database": "OMA" } ], "glygen_name": "Fruit fly", "common_name": "Fruit fly" } ], "go_annotation": { "categories": [ { "name": "Biological Process", "total": 2, "go_terms": [ { "name": "intracellular protein transport", "id": "GO:0006886", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006886", "evidence": [ { "database": "UniProtKB", "id": "A0AAA9TVP9", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TVP9" } ], "pmid": "" }, { "name": "vesicle tethering to Golgi", "id": "GO:0099041", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0099041", "evidence": [ { "database": "UniProtKB", "id": "A0AAA9TVP9", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TVP9" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 2, "go_terms": [ { "name": "cytoplasmic vesicle", "id": "GO:0031410", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0031410", "evidence": [ { "database": "UniProtKB", "id": "A0AAA9TVP9", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TVP9" } ], "pmid": "" }, { "name": "trans-Golgi network", "id": "GO:0005802", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005802", "evidence": [ { "database": "UniProtKB", "id": "A0AAA9TVP9", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TVP9" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 117, "end_pos": 119, "annotation": "n_glycosylation_sequon" }, { "start_pos": 369, "end_pos": 371, "annotation": "n_glycosylation_sequon" }, { "start_pos": 394, "end_pos": 396, "annotation": "n_glycosylation_sequon" }, { "start_pos": 497, "end_pos": 499, "annotation": "n_glycosylation_sequon" }, { "start_pos": 660, "end_pos": 662, "annotation": "n_glycosylation_sequon" }, { "start_pos": 689, "end_pos": 691, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A0AAA9TVP9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TVP9" }, { "id": "PF14648", "database": "Pfam", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF14648" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "FAM91 C-terminal", "eco_id": "ECO_0000259", "start_pos": 375, "end_pos": 820, "start_aa": "Thr", "end_aa": "Thr", "glycosite_overlap": [] }, { "evidence": [ { "id": "A0AAA9TVP9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TVP9" }, { "id": "PF14647", "database": "Pfam", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF14647" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "FAM91 N-terminal", "eco_id": "ECO_0000259", "start_pos": 8, "end_pos": 312, "start_aa": "His", "end_aa": "Lys", "glycosite_overlap": [] } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" }, { "name": "homologset.oma", "label": "OMA Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 117, "end_pos": 119 }, { "start_pos": 369, "end_pos": 371 }, { "start_pos": 394, "end_pos": 396 }, { "start_pos": 497, "end_pos": 499 }, { "start_pos": 660, "end_pos": 662 }, { "start_pos": 689, "end_pos": 691 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ], "tool_support": { "graph_view": "yes" } }, { "uniprot_canonical_ac": "A0AAA9TVA1-1", "uniprot_ac": "A0AAA9TVA1", "uniprot_id": "A0AAA9TVA1_BOVIN", "mass": { "chemical_mass": 59583.0, "monoisotopic_mass": 59583.0 }, "refseq": {}, "gene_names": [ { "name": "PLEKHD1", "type": "recommended", "evidence": [ { "id": "A0AAA9TVA1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TVA1" } ] } ], "protein_names": [ { "name": "Pleckstrin homology and coiled-coil domain containing D1", "type": "synonym", "evidence": [ { "id": "A0AAA9TVA1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TVA1/entry#names_and_taxonomy" } ] } ], "function": [], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Bos taurus", "taxid": 9913, "evidence": [ { "database": "UniProtKB", "id": "A0AAA9TVA1", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TVA1" } ], "common_name": "Bovine", "glygen_name": "Bovine", "reference_species": "Bos taurus [9913]" } ], "gene": [ { "name": "PLEKHD1", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TVA1", "locus": { "chromosome": "10", "start_pos": 81292310, "end_pos": 81244412, "strand": "-", "evidence": [ { "database": "Ensembl Gene", "id": "ENSBTAG00000008576", "url": "https://www.ensembl.org/id/ENSBTAG00000008576" } ] } } ], "crossref": [ { "id": "A0AAA9TVA1", "url": "https://alphafold.ebi.ac.uk/entry/A0AAA9TVA1", "database": "AlphaFoldDB", "categories": [] }, { "id": "ENSBTAG00000008576", "url": "https://bgee.org/?page=gene&gene_id=ENSBTAG00000008576", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "cd13281", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd13281", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "IPR001849", "url": "https://www.ebi.ac.uk/interpro/entry/IPR001849", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR011993", "url": "https://www.ebi.ac.uk/interpro/entry/IPR011993", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "F1MZF1", "url": "https://www.orthodb.org/?gene=F1MZF1", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR14383", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR14383", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR14383:SF1", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR14383:SF1", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00169", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00169", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "A0AAA9T034", "url": "https://www.uniprot.org/uniprotkb/A0AAA9T034", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0AAA9T034-1", "url": "https://www.uniprot.org/uniprotkb/A0AAA9T034-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0AAA9TVA1", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TVA1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0AAA9TVA1-1", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TVA1-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "F1MZF1", "url": "https://www.uniprot.org/uniprotkb/F1MZF1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "F1MZF1-1", "url": "https://www.uniprot.org/uniprotkb/F1MZF1-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MFTSKSNSVSPSPSLEQADSDALDISTKVQLYGVLWKRSFGRPSAKWSRRFCIIKESFLLYYSESEKKSFETNKYFNIHPKGVIPLGGCLVEAKEEPSMPYAMKISHQDFHGTILLAAESEFEQTQWLEMLQESGKVTWKNAQLGEAMIKSLEAQGLQLAKEKQEYLDKLMEETEELCLQREQREALERLNQVLEAEKQQFEEVVQELRMEQEQIKRWLWELELTARCLKGVEQEKKELRHFTESLQKTLEELSIEKKKTLEMLEENENQLQTLANQSEQPPPSGGLHSNLRQIEEKMQQLLEEKLLAEKRMKENEERSRALEEEREFYSSQSQALQNSLQELTVEKQQAERELKAEVKVRMDLERRLREAEGALRSLEQGLNSKVRNKEKEERMRADVSHLKRFFEECIRNAELEAKMPVIMKNSVYIHKAATRRIKSCRFHRRRSSTSWNDVKPSQSFMTSQLEANNMEELKEVAKRLSRDQRFRESIYHIMATQPGAPSALPRGGK", "length": 509, "header": "tr|A0AAA9TVA1-1|A0AAA9TVA1_BOVIN Isoform 1 of Pleckstrin homology and coiled-coil domain containing D1 OS=Bos taurus OX=9913 GN=PLEKHD1 PE=4 SV=2 CANONICAL=A0AAA9TVA1-1" }, "isoforms": [ { "isoform_ac": "A0AAA9T034-1", "url": "https://www.uniprot.org/uniprotkb/A0AAA9T034/entry", "sequence": { "sequence": "MFTSKSNSVSPSPSLEQADSDALDISTKVQLYGVLWKRSFGRPSAKWSRRFCIIKESFLLYYSESEKKSFETNKYFNIHPKGVIPLGGCLVEAKEEPSMPYAMKISHQDFHGTILLAAESEFEQTQWLEMLQESGKVTWKNAQLGEAMIKSLEAQGLQLAKEKQEYLDKLMEETEELCLQREQREALERLNQVLEAEKQQFEEVVQELRMEQEQIKRELELTARCLKGVEQEKKELRHFTESLQKTLEELSIEKKKTLEMLEENENQLQTLANQSEQPPPSGGLHSNLRQIEEKMQQLLEEKLLAEKRMKENEERSRALEEEREFYSSQSQALQNSLQELTVEKQQAERELKAEVKVRMDLERRLREAEGALRSLEQGLNSKVRNKEKEERMRADVSHLKRFFEECIRNAELEAKMPVIMKNSVYIHKAATRRIKSCRFHRRRSSTSWNDATEAEAPILWPPDAKSQLIGKSPEARKD", "length": 478, "header": "tr|A0AAA9T034-1|A0AAA9TVA1_BOVIN Computationally mapped isoform of Pleckstrin homology and coiled-coil domain containing D1 OS=Bos taurus OX=9913 GN=PLEKHD1 PE=4 SV=1 CANONICAL=A0AAA9TVA1-1" }, "locus": { "chromosome": "10", "start_pos": 81292293, "end_pos": 81245510, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000089836.2", "url": "https://www.ensembl.org/id/ENSBTAT00000089836.2" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000092095.1", "url": "https://www.ensembl.org/id/ENSBTAP00000092095.1" } ] } }, { "isoform_ac": "A0AAA9TVA1-1", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TVA1/entry", "sequence": { "sequence": "MFTSKSNSVSPSPSLEQADSDALDISTKVQLYGVLWKRSFGRPSAKWSRRFCIIKESFLLYYSESEKKSFETNKYFNIHPKGVIPLGGCLVEAKEEPSMPYAMKISHQDFHGTILLAAESEFEQTQWLEMLQESGKVTWKNAQLGEAMIKSLEAQGLQLAKEKQEYLDKLMEETEELCLQREQREALERLNQVLEAEKQQFEEVVQELRMEQEQIKRWLWELELTARCLKGVEQEKKELRHFTESLQKTLEELSIEKKKTLEMLEENENQLQTLANQSEQPPPSGGLHSNLRQIEEKMQQLLEEKLLAEKRMKENEERSRALEEEREFYSSQSQALQNSLQELTVEKQQAERELKAEVKVRMDLERRLREAEGALRSLEQGLNSKVRNKEKEERMRADVSHLKRFFEECIRNAELEAKMPVIMKNSVYIHKAATRRIKSCRFHRRRSSTSWNDVKPSQSFMTSQLEANNMEELKEVAKRLSRDQRFRESIYHIMATQPGAPSALPRGGK", "length": 509, "header": "tr|A0AAA9TVA1-1|A0AAA9TVA1_BOVIN Isoform 1 of Pleckstrin homology and coiled-coil domain containing D1 OS=Bos taurus OX=9913 GN=PLEKHD1 PE=4 SV=2 CANONICAL=A0AAA9TVA1-1" }, "locus": { "chromosome": "10", "start_pos": 81275914, "end_pos": 81245510, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000119267.2", "url": "https://www.ensembl.org/id/ENSBTAT00000119267.2" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000100505.2", "url": "https://www.ensembl.org/id/ENSBTAP00000100505.2" } ] } }, { "isoform_ac": "F1MZF1-1", "url": "https://www.uniprot.org/uniprotkb/F1MZF1/entry", "sequence": { "sequence": "MESPFPAGARAPAEVSPGSLPCPRRFCIIKESFLLYYSESEKKSFETNKYFNIHPKGVIPLGGCLVEAKEEPSMPYAMKISHQDFHGTILLAAESEFEQTQWLEMLQESGKVTWKNAQLGEAMIKSLEAQGLQLAKEKQEYLDKLMEETEELCLQREQREALERLNQVLEAEKQQFEEVVQELRMEQEQIKRELELTARCLKGVEQEKKELRHFTESLQKTLEELSIEKKKTLEMLEENENQLQTLANQSEQPPPSGGLHSNLRQIEEKMQQLLEEKLLAEKRMKENEERSRALEEEREFYSSQSQALQNSLQELTVEKQQAERELKAEVKVRMDLERRLREAEGALRSLEQGLNSKVRNKEKEERMRADVSHLKRFFEECIRNAELEAKMPVIMKNSVYIHKAATRRIKSCRFHRRRSSTSWNDVKPSQSFMTSQLEANNMEELKEVAKRLSRDQRFRESIYHIMATQPGAPSALPRGGK", "length": 481, "header": "tr|F1MZF1-1|A0AAA9TVA1_BOVIN Computationally mapped isoform of Pleckstrin homology and coiled-coil domain containing D1 OS=Bos taurus OX=9913 GN=PLEKHD1 PE=4 SV=3 CANONICAL=A0AAA9TVA1-1" }, "locus": { "chromosome": "10", "start_pos": 81275914, "end_pos": 81244716, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000011311.8", "url": "https://www.ensembl.org/id/ENSBTAT00000011311.8" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000011311.6", "url": "https://www.ensembl.org/id/ENSBTAP00000011311.6" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [], "orthologs": [], "go_annotation": {}, "pro_annotation": [], "site_annotation": [ { "start_pos": 276, "end_pos": 278, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A0AAA9TVA1", "database": "UniProtKB", "url": 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"PTHR23234", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR23234", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR23234:SF8", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR23234:SF8", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR24381", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR24381", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR24381:SF462", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR24381:SF462", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00096", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00096", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF01352", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF01352", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "A0AAA9TAI6", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TAI6", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0AAA9TAI6-1", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TAI6-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0AAA9TT24", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TT24", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0AAA9TT24-1", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TT24-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0ABI0NNL9", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NNL9", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0ABI0NNL9-1", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NNL9-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "F1MIK2", "url": "https://www.uniprot.org/uniprotkb/F1MIK2", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "F1MIK2-1", "url": "https://www.uniprot.org/uniprotkb/F1MIK2-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MTRSKGWLTFQDVAIDFTQEEWECLDLGQRELYRDVMLENYGNLASLGLVSKLDLVTFLEQLEDPRNIRRMGTTAIYPAMSPQDTQHLLLKNPALEDVFPKPNLRICQTFHLRNLNLLKDWEYTRVNERQRGCLYGYKEMKTVIRNANVTGKINDQRVPKWEKHQVQSSTSTEKCRCLRKDVPPFLKHTCSLKGNMENLKGNLVSTANTHSDNSEGRLRLNMHSSMSEYLQFNNERTNSQFNQFEGSLRRGSFFFPQKIFSLHSKMYNVDDNGRDALQPSLFSTSRDMVNTQELCMYNKMSQALRKSSSSNNHRSIYGGVRRYSGSETGYMVEGDSNLMKHRGPESSNKDSKSKTFRNTFDQMAGFSLDKSTCSEERTFCEYGKVSNQSSELIQQQTVQNPQKENKGNICGNVFSKASNLSKHRKIHTGRKPFKCTDCSKAFNRRSHLTQHQRIHTGEKPYKCVECGKVFPYSSSLTEHQRIHTGERPYKCTECSVAFVCSSHLTYHQRIHTGEKPYKCKECNRAFHSRSLLNRHQRIHSGERPYKCKECNKAFFLPSHLMKHQRIHTGERPYECKERIKTFILSSHLTQHQQIHTGEKTYHCTQCGQTFICHSKLIVHHRIHTREKPYKYKECGKAFFTSSDLCHHQRIHRADRRYQCTECGKAFITRSRLTKHQRIHTGERPYSCVECGKAFTCNSTLTEHWRIHTGERPHKCKDCNKAFHRRSLLTQHQRVHTGERPYKCTECGKAFGRYSTLSTHQRIHTGERPYKCTACGKAFSRSDHLSKHLRTHTRQKR", "length": 796, "header": "tr|A0AAA9TT24-1|A0AAA9TT24_BOVIN Isoform 1 of Uncharacterized protein OS=Bos taurus OX=9913 GN= PE=3 SV=2 CANONICAL=A0AAA9TT24-1" }, "isoforms": [ { "isoform_ac": "A0AAA9TAI6-1", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TAI6/entry", "sequence": { "sequence": "MSPQDTQHLLLKNPALEDVFPKPNLRICQTFHLRNLNLLKDWEYTRVNERQRGCLYGYKEMKTVIRNANVTGKINDQRVPKWEKHQVQSSTSTEKCRCLRKDVPPFLKHTCSLKGNMENLKGNLVSTANTHSDNSEGRLRLNMHSSMSEYLQFNNERTNSQFNQFEGSLRRGSFFFPQKIFSLHSKMYNVDDNGRDALQPSLFSTSRDMVNTQELCMYNKMSQALRKSSSSNNHRSIYGGVRRYSGSETGYMVEGDSNLMKHRGPESSNKDSKSKTFRNTFDQMAGFSLDKSTCSEERTFCEYGKVSNQSSELIQQQTVQNPQKENKGNICGNVFSKASNLSKHRKIHTGRKPFKCTDCSKAFNRRSHLTQHQRIHTGEKPYKCVECGKVFPYSSSLTEHQRIHTGERPYKCTECSVAFVCSSHLTYHQRIHTGEKPYKCKECNRAFHSRSLLNRHQRIHSGERPYKCKECNKAFFLPSHLMKHQRIHTGERPYECKERIKTFILSSHLTQHQQIHTGEKTYHCTQCGQTFICHSKLIVHHRIHTREKPYKYKECGKAFFTSSDLCHHQRIHRADRRYQCTECGKAFITRSRLTKHQRIHTGERPYSCVECGKAFTCNSTLTEHWRIHTGERPHKCKDCNKAFHRRSLLTQHQRVHTGERPYKCTECGKAFGRYSTLSTHQRIHTGERPYKCTACGKAFSRSDHLSKHLRTHTRQKR", "length": 717, "header": "tr|A0AAA9TAI6-1|A0AAA9TT24_BOVIN Computationally mapped isoform of Uncharacterized protein OS=Bos taurus OX=9913 GN= PE=3 SV=2 CANONICAL=A0AAA9TT24-1" }, "locus": { "chromosome": "18", "start_pos": 60648098, "end_pos": 60645948, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000130789.2", "url": "https://www.ensembl.org/id/ENSBTAT00000130789.2" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000095715.2", "url": "https://www.ensembl.org/id/ENSBTAP00000095715.2" } ] } }, { "isoform_ac": "A0AAA9TT24-1", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TT24/entry", "sequence": { "sequence": "MTRSKGWLTFQDVAIDFTQEEWECLDLGQRELYRDVMLENYGNLASLGLVSKLDLVTFLEQLEDPRNIRRMGTTAIYPAMSPQDTQHLLLKNPALEDVFPKPNLRICQTFHLRNLNLLKDWEYTRVNERQRGCLYGYKEMKTVIRNANVTGKINDQRVPKWEKHQVQSSTSTEKCRCLRKDVPPFLKHTCSLKGNMENLKGNLVSTANTHSDNSEGRLRLNMHSSMSEYLQFNNERTNSQFNQFEGSLRRGSFFFPQKIFSLHSKMYNVDDNGRDALQPSLFSTSRDMVNTQELCMYNKMSQALRKSSSSNNHRSIYGGVRRYSGSETGYMVEGDSNLMKHRGPESSNKDSKSKTFRNTFDQMAGFSLDKSTCSEERTFCEYGKVSNQSSELIQQQTVQNPQKENKGNICGNVFSKASNLSKHRKIHTGRKPFKCTDCSKAFNRRSHLTQHQRIHTGEKPYKCVECGKVFPYSSSLTEHQRIHTGERPYKCTECSVAFVCSSHLTYHQRIHTGEKPYKCKECNRAFHSRSLLNRHQRIHSGERPYKCKECNKAFFLPSHLMKHQRIHTGERPYECKERIKTFILSSHLTQHQQIHTGEKTYHCTQCGQTFICHSKLIVHHRIHTREKPYKYKECGKAFFTSSDLCHHQRIHRADRRYQCTECGKAFITRSRLTKHQRIHTGERPYSCVECGKAFTCNSTLTEHWRIHTGERPHKCKDCNKAFHRRSLLTQHQRVHTGERPYKCTECGKAFGRYSTLSTHQRIHTGERPYKCTACGKAFSRSDHLSKHLRTHTRQKR", "length": 796, "header": "tr|A0AAA9TT24-1|A0AAA9TT24_BOVIN Isoform 1 of Uncharacterized protein OS=Bos taurus OX=9913 GN= PE=3 SV=2 CANONICAL=A0AAA9TT24-1" }, "locus": { "chromosome": "18", "start_pos": 60689965, "end_pos": 60645948, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000101832.2", "url": "https://www.ensembl.org/id/ENSBTAT00000101832.2" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000100493.2", "url": "https://www.ensembl.org/id/ENSBTAP00000100493.2" } ] } }, { "isoform_ac": "A0ABI0NNL9-1", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NNL9/entry", "sequence": { "sequence": "MAASQGRLTFQDVAIDFTQEEWECLDLGQRELYRDVMLENYGNLASLGLVSKLDLVTFLEQLDDPRNIRRMGTTAIYPGVSPQDTQDLMPKNPALEGLFPKANVRIYQTFHLGNLNLMKDREYTRVNEGQRGCLYGHKEMETLIHNANVTGKINDQRASNWEKHQVQSSTSTEKCKFLRKDVPPFLKHTCSLKRNMENLKGNLVSTAKTDSDNSERRLRLNMHSSMSEYLQFNNERSNSQFNQFEGSVSRGSFFFPQEIFSFHFKVCNVDDNGRDAIQPSLFSTYRDMVNIQQLCMYNKMSQALRKSSSSNNHRSIYGGVRRYSGSETGSTVEGDSNLMKHQEPESSNKDSKSKTFRNTFDQMAHFSLDKSTCSKERTCHEYGKVSNQSSELIQQQTVQNPQKENKGNICGNVFSKASNLSKHRKIHTGRKPFKCTDCSKAFNRRFTSYSTSANSHWRETL", "length": 461, "header": "tr|A0ABI0NNL9-1|A0ABI0NNL9_BOVIN Computationally mapped isoform of Uncharacterized protein OS=Bos taurus OX=9913 GN= PE=4 SV=1 CANONICAL=A0AAA9TT24-1" }, "locus": { "chromosome": "18", "start_pos": 60663619, "end_pos": 60623791, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000152555.1", "url": "https://www.ensembl.org/id/ENSBTAT00000152555.1" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000107006.1", "url": "https://www.ensembl.org/id/ENSBTAP00000107006.1" } ] } }, { "isoform_ac": "F1MIK2-1", "url": "https://www.uniprot.org/uniprotkb/F1MIK2/entry", "sequence": { "sequence": "MTRSKGWLTFQDVAIDFTQEEWECLDLGQRELYRDVMLENYGNLASLGLVSKLDLVTFLEQLDDPRNIRRMGTTAIYPAMSPQDTQHLLLKNPALEDVFPKPNLRICQTFHLRNLNLLKDWEYTRVNERQRGCLYGYKEMKTVIRNANVTGKINDQRVPKWEKHQVQSSTSTEKCRCLRKDVPPFLKHTCSLKGNMENLKGNLVSTANTHSDNSEGRLRLNMHSSMSEYLQFNNERTNSQFNQFEGSLRRGSFFFPQKIFSLHSKMYNVDDNGRDALQPSLFSTSRDMVNTQELCMYNKMSQALRKSSSSNNHRSIYGGVRRYSGSETGYMVEGDSNLMKHRGPESSNKDSKSKTFRNTFDQMAGFSLDKSTCSEERTFCEYGKVSNQSSELIQQQTVQNPQKENKGNICGNVFSKASNLSKHRKIHTGRKPFKCTDCSKAFNRRSHLTQHQRIHTGEKPYKCVECGKVFPYSSSLTEHQRIHTGERPYKCTECSVAFVCSSHLTYHQRIHTGEKPYKCKECNRAFHSRSLLNRHQRIHSGERPYKCKECNKAFFLPSHLMKHQRIHTGERPYECKERIKTFILSSHLTQHQQIHTGEKTYHCTQCGQTFICHSKLIVHHRIHTREKPYKYKECGKAFFTSSDLCHHQRIHRADRRYQCTECGKAFITRSRLTKHQRIHTGERPYSCVECGKAFTCNSTLTEHWRIHTGERPHKCKDCNKAFHRRSLLTQHQRVHTGERPYKCTECGKAFGRYSTLSTHQRIHTGERPYKCTACGKAFSRSDHLSKHLRTHTRQKR", "length": 796, "header": "tr|F1MIK2-1|A0AAA9TT24_BOVIN Computationally mapped isoform of Uncharacterized protein OS=Bos taurus OX=9913 GN= PE=3 SV=5 CANONICAL=A0AAA9TT24-1" }, "locus": { "chromosome": "18", "start_pos": 60689965, "end_pos": 60645948, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000056208.5", "url": "https://www.ensembl.org/id/ENSBTAT00000056208.5" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000049568.5", "url": "https://www.ensembl.org/id/ENSBTAP00000049568.5" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [], "orthologs": [], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 1, "go_terms": [ { "name": "nucleus", "id": "GO:0005634", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005634", "evidence": [ { "database": "UniProtKB", "id": "A0AAA9TT24", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TT24" } ], "pmid": "" } ] }, { "name": "Molecular Function", "total": 2, "go_terms": [ { "name": "zinc ion binding", "id": "GO:0008270", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008270", "evidence": [ { "database": "UniProtKB", "id": "A0AAA9TT24", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TT24" } ], "pmid": "" }, { "name": "transcription cis-regulatory region binding", "id": "GO:0000976", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000976", "evidence": [ { "database": "UniProtKB", "id": "A0AAA9TT24", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TT24" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 2, "go_terms": [ { "name": "regulation of DNA-templated transcription", "id": "GO:0006355", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006355", "evidence": [ { "database": "UniProtKB", "id": "A0AAA9TT24", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TT24" } ], "pmid": "" }, { "name": "regulation of transcription by RNA polymerase II", "id": "GO:0006357", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006357", "evidence": [ { "database": "UniProtKB", "id": "A0AAA9TT24", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TT24" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 148, "end_pos": 150, "annotation": "n_glycosylation_sequon" }, { "start_pos": 387, "end_pos": 389, "annotation": "n_glycosylation_sequon" }, { "start_pos": 419, "end_pos": 421, "annotation": "n_glycosylation_sequon" }, { "start_pos": 697, "end_pos": 699, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A0AAA9TT24", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TT24" }, { "id": "PS50157", "database": "PROSITE", "url": "https://prosite.expasy.org/PS50157" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "C2H2-type", "eco_id": "ECO_0000259", "start_pos": 405, "end_pos": 432, "start_aa": "Asn", "end_aa": "Pro", "glycosite_overlap": [] }, { "evidence": [ { "id": "A0AAA9TT24", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TT24" }, { "id": "PS50805", "database": "PROSITE", "url": "https://prosite.expasy.org/PS50805" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "KRAB", "eco_id": "ECO_0000259", "start_pos": 8, "end_pos": 78, "start_aa": "Leu", "end_aa": "Pro", "glycosite_overlap": [] } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 148, "end_pos": 150 }, { "start_pos": 387, "end_pos": 389 }, { "start_pos": 419, "end_pos": 421 }, { "start_pos": 697, "end_pos": 699 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ], "tool_support": { "graph_view": "yes" } }, { "uniprot_canonical_ac": "A0AAA9TVQ8-1", "uniprot_ac": "A0AAA9TVQ8", "uniprot_id": "A0AAA9TVQ8_BOVIN", "mass": { "chemical_mass": 23843.0, "monoisotopic_mass": 23843.0 }, "refseq": {}, "gene_names": [ { "name": "CMC1", "type": "recommended", "evidence": [ { "id": "A0AAA9TVQ8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TVQ8" } ] } ], "protein_names": [ { "name": "C-X9-C motif containing 1", "type": "synonym", "evidence": [ { "id": "A0AAA9TVQ8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TVQ8/entry#names_and_taxonomy" } ] } ], "function": [], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Bos taurus", "taxid": 9913, "evidence": [ { "database": "UniProtKB", "id": "A0AAA9TVQ8", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TVQ8" } ], "common_name": "Bovine", "glygen_name": "Bovine", "reference_species": "Bos taurus [9913]" } ], "gene": [ { "name": "CMC1", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TVQ8", "locus": { "chromosome": "22", "start_pos": 2754961, "end_pos": 2675935, "strand": "-", "evidence": [ { "database": "Ensembl Gene", "id": "ENSBTAG00000035286", "url": "https://www.ensembl.org/id/ENSBTAG00000035286" } ] } } ], "crossref": [ { "id": "A0AAA9TVQ8", "url": "https://alphafold.ebi.ac.uk/entry/A0AAA9TVQ8", "database": "AlphaFoldDB", "categories": [] }, { "id": "IPR013892", "url": "https://www.ebi.ac.uk/interpro/entry/IPR013892", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "PTHR22977", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR22977", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR22977:SF5", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR22977:SF5", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF08583", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF08583", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "A0AAA9TB39", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TB39", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0AAA9TB39-1", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TB39-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0AAA9TVQ8", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TVQ8", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0AAA9TVQ8-1", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TVQ8-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0AAA9U123", "url": "https://www.uniprot.org/uniprotkb/A0AAA9U123", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0AAA9U123-1", "url": "https://www.uniprot.org/uniprotkb/A0AAA9U123-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0AAF6Z613", "url": "https://www.uniprot.org/uniprotkb/A0AAF6Z613", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0AAF6Z613-1", "url": "https://www.uniprot.org/uniprotkb/A0AAF6Z613-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0ABI0P6C1", "url": "https://www.uniprot.org/uniprotkb/A0ABI0P6C1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0ABI0P6C1-1", "url": "https://www.uniprot.org/uniprotkb/A0ABI0P6C1-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "ATSKTQAGSRLTGSRPARLRGPGGHALSRGFPRESPSAPVTPLGTGRECAGAAGGGSRDREVRGAGAASLCAGRRAPPLAPVGRPAPPPVRPRPTHSRRRPRGCRLPRVDMALDPSEQHLRHVEKDVLIPKIMREKARERCSEQVQDFTKCCKDSGVLMVVKCRKENSALKDCLTSYYKDPAFYEECKMEYLKEREEFRRTGIPTKKRLQKLPTSM", "length": 216, "header": "tr|A0AAA9TVQ8-1|A0AAA9TVQ8_BOVIN Isoform 1 of C-X9-C motif containing 1 OS=Bos taurus OX=9913 GN=CMC1 PE=3 SV=1 CANONICAL=A0AAA9TVQ8-1" }, "isoforms": [ { "isoform_ac": "A0AAA9TB39-1", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TB39/entry", "sequence": { "sequence": "MALDPSVFPVHVSRYICEERSLGVNPPGPAFVGFEVRACGWSLPEQHLRHVEKDVLIPKIMREKARERCSEQVQDFTKCCKDSGVLMVVKCRKENSALKDCLTSYYKDPAFYEECKMEYLKEREEFRRTGIPTKKRLQKLPTSM", "length": 144, "header": "tr|A0AAA9TB39-1|A0AAA9TVQ8_BOVIN Computationally mapped isoform of C-X9-C motif containing 1 OS=Bos taurus OX=9913 GN=CMC1 PE=3 SV=1 CANONICAL=A0AAA9TVQ8-1" }, "locus": { "chromosome": "22", "start_pos": 2752399, "end_pos": 2676464, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000109911.2", "url": "https://www.ensembl.org/id/ENSBTAT00000109911.2" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000093272.1", "url": "https://www.ensembl.org/id/ENSBTAP00000093272.1" } ] } }, { "isoform_ac": "A0AAA9TVQ8-1", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TVQ8/entry", "sequence": { "sequence": "ATSKTQAGSRLTGSRPARLRGPGGHALSRGFPRESPSAPVTPLGTGRECAGAAGGGSRDREVRGAGAASLCAGRRAPPLAPVGRPAPPPVRPRPTHSRRRPRGCRLPRVDMALDPSEQHLRHVEKDVLIPKIMREKARERCSEQVQDFTKCCKDSGVLMVVKCRKENSALKDCLTSYYKDPAFYEECKMEYLKEREEFRRTGIPTKKRLQKLPTSM", "length": 216, "header": "tr|A0AAA9TVQ8-1|A0AAA9TVQ8_BOVIN Isoform 1 of C-X9-C motif containing 1 OS=Bos taurus OX=9913 GN=CMC1 PE=3 SV=1 CANONICAL=A0AAA9TVQ8-1" }, "locus": { "chromosome": "22", "start_pos": 2752399, "end_pos": 2676134, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000112730.2", "url": "https://www.ensembl.org/id/ENSBTAT00000112730.2" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000101243.1", "url": "https://www.ensembl.org/id/ENSBTAP00000101243.1" } ] } }, { "isoform_ac": "A0AAA9U123-1", "url": "https://www.uniprot.org/uniprotkb/A0AAA9U123/entry", "sequence": { "sequence": "MHMCLKQHLRHVEKDVLIPKIMREKARERCSEQVQDFTKCCKDSGVLMVVKCRKENSALKDCLTSYYKDPAFYEECKMEYLKEREEFRRTGIPTKKRLQKLPTSM", "length": 105, "header": "tr|A0AAA9U123-1|A0AAA9U123_BOVIN Computationally mapped isoform of COX assembly mitochondrial protein OS=Bos taurus OX=9913 GN=CMC1 PE=3 SV=1 CANONICAL=A0AAA9TVQ8-1" }, "locus": { "chromosome": "22", "start_pos": 2752399, "end_pos": 2683851, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000129760.2", "url": "https://www.ensembl.org/id/ENSBTAT00000129760.2" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000102855.1", "url": "https://www.ensembl.org/id/ENSBTAP00000102855.1" } ] } }, { "isoform_ac": "A0AAF6Z613-1", "url": "https://www.uniprot.org/uniprotkb/A0AAF6Z613/entry", "sequence": { "sequence": "MALDPSDFTKCCKDSGVLMVVKCRKENSALKDCLTSYYKDPAFYEECKMEYLKEREEFRRTGIPTKKRLQKLPTSM", "length": 76, "header": "tr|A0AAF6Z613-1|A0AAF6Z613_BOVIN Computationally mapped isoform of COX assembly mitochondrial protein OS=Bos taurus OX=9913 GN=CMC1 PE=3 SV=1 CANONICAL=A0AAA9TVQ8-1" }, "locus": { "chromosome": "22", "start_pos": 2752399, "end_pos": 2676464, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000025040.7", "url": "https://www.ensembl.org/id/ENSBTAT00000025040.7" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000025040.6", "url": "https://www.ensembl.org/id/ENSBTAP00000025040.6" } ] } }, { "isoform_ac": "A0ABI0P6C1-1", "url": "https://www.uniprot.org/uniprotkb/A0ABI0P6C1/entry", "sequence": { "sequence": "MASINWSGTEVYYEIKNEAELPSRGSVLTQHMWKQDFTKCCKDSGVLMVVKCRKENSALKDCLTSYYKDPAFYEECKMEYLKEREEFRRTGIPTKKRLQKLPTSM", "length": 105, "header": "tr|A0ABI0P6C1-1|A0ABI0P6C1_BOVIN Computationally mapped isoform of COX assembly mitochondrial protein OS=Bos taurus OX=9913 GN=CMC1 PE=3 SV=1 CANONICAL=A0AAA9TVQ8-1" }, "locus": { "chromosome": "22", "start_pos": 2752399, "end_pos": 2717139, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000140853.1", "url": "https://www.ensembl.org/id/ENSBTAT00000140853.1" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000107317.1", "url": "https://www.ensembl.org/id/ENSBTAP00000107317.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [], "orthologs": [], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 1, "go_terms": [ { "name": "mitochondrion", "id": "GO:0005739", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005739", "evidence": [ { "database": "UniProtKB", "id": "A0AAA9TVQ8", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TVQ8" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ], "tool_support": { "graph_view": "yes" } }, { "uniprot_canonical_ac": "A0AAA9TV11-1", "uniprot_ac": "A0AAA9TV11", "uniprot_id": "A0AAA9TV11_BOVIN", "mass": { "chemical_mass": 69828.0, "monoisotopic_mass": 69828.0 }, "refseq": { "ac": "XP_010809473", "name": "protein adenylyltransferase SelO isoform X1", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_010809473" }, "gene_names": [ { "name": "LOC100297097", "type": "recommended", "evidence": [ { "id": "A0AAA9TV11", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TV11" } ] }, { "name": "LOC100297097", "type": "synonym", "evidence": [ { "id": "XP_010809473", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_010809473" } ] } ], "protein_names": [ { "name": "Selenoprotein O", "type": "recommended", "evidence": [ { "id": "A0AAA9TV11", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TV11/entry#names_and_taxonomy" } ] }, { "name": "protein adenylyltransferase SelO isoform X1", "type": "synonym", "evidence": [ { "id": "XP_010809473", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_010809473" } ] } ], "function": [], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Bos taurus", "taxid": 9913, "evidence": [ { "database": "UniProtKB", "id": "A0AAA9TV11", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TV11" } ], "common_name": "Bovine", "glygen_name": "Bovine", "reference_species": "Bos taurus [9913]" } ], "gene": [ { "name": "LOC100297097", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TV11", "locus": {} } ], "crossref": [ { "id": "A0AAA9TV11", "url": "https://alphafold.ebi.ac.uk/entry/A0AAA9TV11", "database": "AlphaFoldDB", "categories": [] }, { "id": "100297097", "url": "https://www.ncbi.nlm.nih.gov/gene/100297097", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR003846", "url": "https://www.ebi.ac.uk/interpro/entry/IPR003846", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "PTHR12153", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR12153", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR12153:SF18", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR12153:SF18", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF02696", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF02696", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "XP_010809473", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_010809473", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0AAA9TV11", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TV11", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0AAA9TV11-1", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TV11-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MLRGARRTVLNFPSPFLGENWTQRIKFPFCCLIWRLQFPPLLLLGVTCHAVVGSLWRPSLQGNANLLHLSRNRSNPEQGYCERGARLVSSLDFWTLSSENLIAVLPTDPVKENYVRKVKNCVFSIAFPTPFQSRVRLVAVSKEVLEDILDLDLSVSETDDFIQLVSGGKIVFGSIPLAHRYGGHQFGIWADQLGDGRAHLIGIYMNRQGEKWELQLKGSGKTPYSRNGDGRAILRSSLREFLCSEAMHYLGIPTSRAASLVVSDDVVWRDQFYNGNLTKERGAVVLRVAKSWFRIGSLEILTHSGELDLLRMLLDFIIQEYFPLVDVKEPNRYVDFFSIVVFETAQLIALWMSVGFARGVCNTDNFSLLSITIDYGPFGFMEAYNPDFVPNTSDDERRYKIGNQANIGMFNLNKLLQALNPLLNPRQKQLVTQILKEYPVLYYTRFRELFKAKLGLLGKSEGDDDLIAFLLHLMEKTEADFTMTFRQLSEITQSQLQELVIPQEFWALKMISKHKLFPAWVSQYLSRLKSNISDSDSERRKRMTAVNPRYVLKNWMAESAVQKAERNDFSEVHLLQQVLRHPFQKHSAAERAGYSSPTPSWARDLRVSCSS", "length": 611, "header": "tr|A0AAA9TV11-1|A0AAA9TV11_BOVIN Isoform 1 of Selenoprotein O OS=Bos taurus OX=9913 GN=LOC100297097 PE=3 SV=2 CANONICAL=A0AAA9TV11-1" }, "isoforms": [ { "isoform_ac": "A0AAA9TV11-1", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TV11/entry", "sequence": { "sequence": "MLRGARRTVLNFPSPFLGENWTQRIKFPFCCLIWRLQFPPLLLLGVTCHAVVGSLWRPSLQGNANLLHLSRNRSNPEQGYCERGARLVSSLDFWTLSSENLIAVLPTDPVKENYVRKVKNCVFSIAFPTPFQSRVRLVAVSKEVLEDILDLDLSVSETDDFIQLVSGGKIVFGSIPLAHRYGGHQFGIWADQLGDGRAHLIGIYMNRQGEKWELQLKGSGKTPYSRNGDGRAILRSSLREFLCSEAMHYLGIPTSRAASLVVSDDVVWRDQFYNGNLTKERGAVVLRVAKSWFRIGSLEILTHSGELDLLRMLLDFIIQEYFPLVDVKEPNRYVDFFSIVVFETAQLIALWMSVGFARGVCNTDNFSLLSITIDYGPFGFMEAYNPDFVPNTSDDERRYKIGNQANIGMFNLNKLLQALNPLLNPRQKQLVTQILKEYPVLYYTRFRELFKAKLGLLGKSEGDDDLIAFLLHLMEKTEADFTMTFRQLSEITQSQLQELVIPQEFWALKMISKHKLFPAWVSQYLSRLKSNISDSDSERRKRMTAVNPRYVLKNWMAESAVQKAERNDFSEVHLLQQVLRHPFQKHSAAERAGYSSPTPSWARDLRVSCSS", "length": 611, "header": "tr|A0AAA9TV11-1|A0AAA9TV11_BOVIN Isoform 1 of Selenoprotein O OS=Bos taurus OX=9913 GN=LOC100297097 PE=3 SV=2 CANONICAL=A0AAA9TV11-1" }, "locus": { "chromosome": "13", "start_pos": 17989641, "end_pos": 17957139, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000090046.2", "url": "https://www.ensembl.org/id/ENSBTAT00000090046.2" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000100967.2", "url": "https://www.ensembl.org/id/ENSBTAP00000100967.2" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [], "orthologs": [], "go_annotation": { "categories": [ { "name": "Molecular Function", "total": 3, "go_terms": [ { "name": "ATP binding", "id": "GO:0005524", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005524", "evidence": [ { "database": "UniProtKB", "id": "A0AAA9TV11", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TV11" } ], "pmid": "" }, { "name": "metal ion binding", "id": "GO:0046872", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0046872", "evidence": [ { "database": "UniProtKB", "id": "A0AAA9TV11", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TV11" } ], "pmid": "" }, { "name": "nucleotidyltransferase activity", "id": "GO:0016779", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016779", "evidence": [ { "database": "UniProtKB", "id": "A0AAA9TV11", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TV11" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 20, "end_pos": 22, "annotation": "n_glycosylation_sequon" }, { "start_pos": 276, "end_pos": 278, "annotation": "n_glycosylation_sequon" }, { "start_pos": 365, "end_pos": 367, "annotation": "n_glycosylation_sequon" }, { "start_pos": 391, "end_pos": 393, "annotation": "n_glycosylation_sequon" }, { "start_pos": 531, "end_pos": 533, "annotation": "n_glycosylation_sequon" }, { "start_pos": 72, "end_pos": 74, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], 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"MFHPSSKPLKEGGPIPDVGKGERQEEEEEDGVGPGLPGTLKNCLPRRDFSVLEKLVKTCPVWLQLGLGRVEAARILHREAAGTFLVRRDSSLKHLVLCVHFPSLNESSSEVLEYTIKEEKSILYLEGSVLVFEDIFRLIAFYCVSRDLLPFTLRLPRAILEARSSTDLEIVSNLGLGFWDSSLNPRRGGGSPAEAPRDPAPGATPASSLKSTAHPENCSCEIELSIGNGRLWFVNPIFIEDCDRAPPADQPPAGSCPSRPAPPTPDATSPTSRWAPRRPAPPPPPLPLHPPGFSRPPPAAPTPPASPSPSSPPAAAPPPPEALPPSPPASAPHLAPHAPGPPGLPSQPPMTACERLPRPFAGLDPLREEEMKPGAAASPLKTPAPPVPTKKSLPAVPPRRRISEKVSLEDQSAGKPDRGAAAEGDPGGPSRASPLRLPPLRTSDTPGDRPQRTTEPGQEASAQASNPGSAPEPLRKIRQAPVPPPRKKRVSRQLASVLPTPQETAELSAAGEAPEKPTPGPPPGEIQGPASPAGGNQSPHAPAGARPQSAPEFKGSLASLSDSLGVPASAADQDSYSTSSTEEELEQFSSPGMKKKPSMILGKARHRLSFVSFSNVFNAFLSNNRKLYKKVVELAQDKGSYFGNLVQDYKVYSLEMMSQQTSSTEMLQEIRTMMTQLKSYLLQSTELKALVDPTLHTEEELEAIVESALYKCVLKPLKEAIYSCLHEIHSKDSSLQQLKDNQLVILATTTTDLGVTTSVPEVPVMEKILQKFASMHKAYSPEKKISILLKTCKLIYDSMALGNPGKPYGADDFLPVLMYVLARSNLTEMLLNVEYMMELMDPALQLGEGSYYLTTTYGALEHIKNYDKITVTRQLSVEVQDSIHRWERRRTLNKARASRSSVQDFICVSYLEPEQQSRTLASRADTLAEALCTQCAEKFEVVQPQDYRLFVLVDGRTFQLADEALPHRIKGYLLRSEPKRDFHFVYRPLDGGGGSGGPPCLVVREPNFL", "length": 1009, "header": "tr|G5E5D0-1|G5E5D0_BOVIN Computationally mapped isoform of Ras and Rab interactor 3 OS=Bos taurus OX=9913 GN=RIN3 PE=3 SV=3 CANONICAL=A0AAA9TVZ2-1" }, "locus": { "chromosome": "21", "start_pos": 57367468, "end_pos": 57249451, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000013748.6", "url": "https://www.ensembl.org/id/ENSBTAT00000013748.6" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000013748.6", "url": "https://www.ensembl.org/id/ENSBTAP00000013748.6" } ] } } ], "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "other", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 206, "start_aa": "Thr", "end_pos": 206, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr206", "evidence": [ { "id": "", "database": "GlyGen", "url": "https://data.glygen.org/" } ], "filter_code": "000000000000000010000.00000000001000.0.01000" }, { "glytoucan_ac": "", "type": "O-linked", "subtype": "other", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 266, "start_aa": "Thr", "end_pos": 266, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr266", "evidence": [ { "id": "", "database": "GlyGen", "url": "https://data.glygen.org/" } ], "filter_code": "000000000000000010000.00000000001000.0.01000" }, { "glytoucan_ac": "", "type": "O-linked", "subtype": "other", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 304, "start_aa": "Thr", "end_pos": 304, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr304", "evidence": [ { "id": "", "database": "GlyGen", "url": "https://data.glygen.org/" } ], "filter_code": "000000000000000010000.00000000001000.0.01000" }, { "glytoucan_ac": "", "type": "O-linked", "subtype": "other", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 502, "start_aa": "Thr", "end_pos": 502, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr502", "evidence": [ { "id": "", "database": "GlyGen", "url": "https://data.glygen.org/" } ], "filter_code": "000000000000000010000.00000000001000.0.01000" }, { "glytoucan_ac": "", "type": "O-linked", "subtype": "other", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 520, "start_aa": "Thr", "end_pos": 520, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr520", "evidence": [ { "id": "", "database": "GlyGen", "url": "https://data.glygen.org/" } ], "filter_code": "000000000000000010000.00000000001000.0.01000" } ], "phosphorylation": [], "glycation": [], "keywords": [ "glycoprotein", "glycoprotein_predicted" ], "publication": [], "pathway": [ { "id": "bta:539951", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?bta:539951", "resource": "KEGG Pathway" }, { "id": "R-BTA-8876198", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-BTA-8876198", "resource": "Reactome", "description": "RAB GEFs exchange GTP for GDP on RABs" } ], "orthologs": [ { "uniprot_canonical_ac": "A0A0G2K0G9-1", "protein_name": "Ras and Rab interactor 3", "gene_name": "Rin3", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "ILRANAPSDSQDAGVPFLPIPDAGKGEGEEDEEKDGMRPRLPTTPRNCIPHRGISVLEKLVKTCPVWLQLGIGQAEAAKILQQEMAGMFLVCRDSSLKRLVLCVHFPSLKNTSTEVLEYPIKEEKSILYLEGSVLVFEDIFRLIAFYCVSRDLLPFTLRLPQAILEASSFLELETISNLGLGFWDSSLNSSRGPAEPLRSSAPGTPASSGRPATHLANCSCEIELSVGNDRLWFVNPIFIEDCTLPADPPPLPIGSYPTRPAPAAPDATSLTSKGSPRRPPPPPPVPTVPPTGPAWPPAPPVQPADPLPNSPTPNSHLAPHAPGPPGHSNQPPMTACESLPRPSVGLGPFGEEEMKPGTTPSPLHQAPPPPLPLKKTLPAAPPRRRISERVSLESQNVGTSTDRDRSGISRTASLNLPPQSTVSSLGDRSPRTTEQGQDTEAKASHADSTPVPPGKAKQPPVPPPRKKRVSRQLASTFPSPLTSPIPEVSPEKPAAPGAPWEGLSPAGQAGMQHLQVQTSACPQSSPEFKGSLASLSDSLGVPASAADQDSYSTSSAEEELEFSSPNVKKKPSMILDKARHRLSFASFTSVFHAFLSSDRKLYKKVVELAQDKGSYFGSLVQDYKVYSLEMMTRQTSSTEMLQEIRTMMTQLKSYLLQSTELKALVEPTLHSEEELEAIVESALYKCVLKPLKEAINSSLLEIHSRDGSLQQLKENQLVILATTTTDLGVTTSVPEVAVMEKILQKLTNMHKAYSPGKKISILLKTCKLIYDSMALGNPGKPYGADDFLPVLMYVLARSNLTEMLLNVEYMMELMDPALQLGEGSYYLTTTYGALEHIKNYDKITVTRQLSVEVQDSIHRWERRRTLNKARASRSSVQDFICVSYLQPEQQSRTLASRADTVAQALCAQCAEKFEVAQPQDYRLFVLVDGRCFQLADEALPHRIKGYLLRSEPKRDFHFVYRPQDSGRDASNQPYLVVREPNFL", "length": 984 }, "evidence": [ { "id": "A0AAA9TVZ2", "url": "https://omabrowser.org/oma/group/A0AAA9TVZ2/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "A0A8V0YYW2-1", "protein_name": "Ras and Rab interactor 3", "gene_name": "RIN3", "tax_id": 9031, "organism": "Gallus gallus", "sequence": { "sequence": "MRFICRGYLPCAQSASIKMRHLLSDAPQGAFWMLSALPSSNTSEEGKETHLCQATSLRNCLSLSGISILDKLIKTCPVWLQLNMNQERAAAILGKEAAGMFLVRKEGNANNMVLAVRMPVQSDAPGVLEYNIKEEKSILYLEGAVLVFEDVFKLVAFYCVSRDLLPFTLKLPQAILEARSFQDLEIISSLGIDFWDSSLNRRMSTEALSHPATDSAPSTAQADGLSSTQCVASSANHCSCEIELSIGNDRLWFVNPIFIEECSNPFPPESPPPGGHAVCSSLPPTTTASPRRPPPPPPHSHRQKSSLKLPQEAMTACEETQLLQPLGKSFKEMKIEGGDGEEGKQSCSDKEPSAGSLKKGPQPAVPPRRRMSERTTEECCTGKPASCETPKGEQAEEKQELDTQSEGKRLLCRKAAEMPGEVPEQAVSQFQEAKPEPAEKESMAEVQSDATEKEKLPPIPPPRRKRLSQAPQVASSCQLNHRTVVEQPAATAQAQDTGSSAPAAGAATGTNAETEQGRGRKSVNSAELKGSHLSLEGLGGSPAAQTSASEPDSYSTSSTEDDLEMLGTSSTKKTRSMILGKAKNRLSFVSLSNVFTVFLSNDRKLQKKIVELAQDKDSYFGNLVQDYRVYSLEMMAKQSSSTEMLQEIRMMMTQLKSYLVQSTELKSLIDPAVYTDEQLDVIAESALYKCVLKPLKEAINSHLKEIHNKDGSLQQLKENQLVIQNTTTTDLGVTTSVPETVVLDKILHKFTTMHKAYSPEKKIGILLKSCKLIYDSMSQGNPGKPYGADDFLPVLMYVLARSNLTEVLLNVEYMMELMDPALQLGEGSYYLTTTYGALEHIKNYDKITVTRQLSMEVQDSIHRWERRRTLNKARASRSSVQDFISITFLEIGAQSRTLASRNDTTTEQLCQQCAEKFEVSHPNIYRLFVYVDGQWLQLDKEALPHRIKASLLKSETKKDFHFIYKPVEYKNPPIPIVKETDFS", "length": 983 }, "evidence": [ { "id": "A0AAA9TVZ2", "url": "https://omabrowser.org/oma/group/A0AAA9TVZ2/", "database": "OMA" } ], "glygen_name": "Chicken", "common_name": "Chicken" }, { "uniprot_canonical_ac": "E7FC22-1", "protein_name": "Ras and Rab interactor 3", "gene_name": "rin3", "tax_id": 7955, "organism": "Danio rerio", "sequence": { "sequence": "MISPGPSAAPPGLSSPTISSSIQSSFHPQTSPSTPAFPLVDVSDDPSPDPTTSFLLPVSSPQLNSKPSPPPPHKPMMSPQVPKPPLPAQLPSALPKSSSSGLPRPPPPPTARPSSPPQARPPPPVVPKPPVPTSPVSKSNKPVPPGISILEKLIKTCPVWLQLGMNLDKAMHILSKEFPGIFLVRRDATQKTMVLAVRLPDQLGEPHVKELPVKEEKSLLYLEGSVLVFENIFKLIAFYCVSRDILPFPLKLPQVIQKVAKYEDMEVISSIGSEFWNSTLNSHEDVENVSGSSGSLDRQRQSSSCEIQLSIGSDRLWYVNPIFIEECSNSVSPAASTPVLRTQSLNTPLQAPPKFKRPPPLRPRPPSTPEAPPHHVLAKPSKGEFKAALSSPPSSVKKREGNDCERADREQEKQGTPAPSADCDKPAVLQAAQGKEGKQIFNTASHRVPPIPIRRKLSEKQASEEPAQQEVNPEPEDSTQQVPVASLICLDDGVEERDKPMDPKTPQVQEVPAEESKVANGAPMVTPEVASQPKRPNAPVPPPRKKRQSHCSNLSSSTPQNTTSTVPLKSSSPSPVRHSLCINATHPKVSDVSLYSPDGGAPLDHDSYSTSSTEEEADANMATGALIKRTPTIMLDRAKQRLSMVSMANLSNVLTGFMNADRKLQKRIVEMSRDGNTYFGNLVKDYRAFTLDTMRKHTSSTEMLQEIRQMITQLKSYLIQSAELQNVQETAAYSEEKLEIIIEAAICKSVLKPLREAVYNGLKDIHSRAGNLKKLKENQQVVQGTTTTDLGVITSVPETPIMEKIQTRLGNLHQEYSPQKKIDLLLKTCKIIYESMSVGCPGRAHGADDFLPVLMYVLARCNITALLLDVEYMMELMDPALQLGEGSYYLTTTYGALEHIKNFDKQAVTRQLSLEIQDSIHRWERRRTLNKARASRTSVQDFINVSFLEACSNTKTLGVRPNTTAKDLCSQCAEKFEVLDPESYCLSVLVEGHYNHLAPEEFPLAIKSTLHHSQPRKEYYFVYRHGRWPEQESVDETESTPTAPESLI", "length": 1048 }, "evidence": [ { "id": "A0AAA9TVZ2", "url": "https://omabrowser.org/oma/group/A0AAA9TVZ2/", "database": "OMA" } ], "glygen_name": "Zebrafish", "common_name": "Zebrafish" }, { "uniprot_canonical_ac": "P59729-1", "protein_name": "Ras and Rab interactor 3", "gene_name": "Rin3", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MRRAEAPSSAHPAGPIPDAGKGEGEEDEEKDGTRLGLSTTPRNCIPRRGISVLEKLVKTCPVWLQLGLGQAEAAKILQQEMAGMFLVCRDNNLKQLVLCVHFPSLKGSSAEVLEYPIKEEKAILYLEGSVLVFEDIFRLIAFYCVSRDLLPFTLRLPQAILEASSFLELETISNLGLGFWDSSLNSRGSAEPLRSPAPGTPASSSLRPTTHYANCSCEIELSVGNDRLWFVNPIFIEDCILPADPPPLPTGSYPPRPTPATPDATSPTSKGSPRRPPPPPPLPTVPPTGPARPLAPPVPPAGPLPNSPLTPTSHLAPHAPGPPGHSNQPPMTACESLPRPAVGLGPFGEEEMKPGTTPNPLHQAPPPPLPLKKALPAAPPRRRISERVSLESQNVGTSTDRDHSGISRTASLNLPPQSTVSSLGDRPPRTTEQSQDTEAKASHADSIPVPPGKAKQPPVPPPRKKRVSRQLASTLLSPLESPIQEASSEKQATGASWEGLSPVRQAGMQHLQVQSSSCPQSSPEFKGSQASLSDSLGVPASAADQDSYSTSSAEEELEFSSPNVKKKPSMILDKARHRLSFVSFASVFHAFLSSDRKLYKKVVELAQDKSSYFGSLVQDYKVYSLEMMARQTSSTEMLQEIRTMMTQLKSYLLQSTELKALVEPTLHSEEELEAIVESALYKCVLKPLKEAINSSLLEIHSRDGSLQQLKENQLVVLATTTTDLGVTTSVPEVAVMEKILQKLTSMHKAYSPGKKISILLKTCKLIYDSMALGNPGKPYGADDFLPVLMYVLARSNLTEMLLNVEYMMELMDPALQLGEGSYYLTTTYGALEHIKNYDKITVTRQLSVEVQDSIHRWERRRTLNKARASRSSVQDFICVSYLKPEQQSRTLASRADTAAQALCAQCAEKFEVSQPQDYRLFVLVDGRCFQLADEALPHRIKGYLLRSEPKRDFHFVYRPQDSGKDASSQPCIVVREPNFL", "length": 980 }, "evidence": [ { "id": "A0AAA9TVZ2", "url": "https://omabrowser.org/oma/group/A0AAA9TVZ2/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q8TB24-1", "protein_name": "Ras and Rab interactor 3", "gene_name": "RIN3", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MIRHAGAPARGDPTGPVPVVGKGEEEEEEDGMRLCLPANPKNCLPHRRGISILEKLIKTCPVWLQLSLGQAEVARILHRVVAGMFLVRRDSSSKQLVLCVHFPSLNESSAEVLEYTIKEEKSILYLEGSALVFEDIFRLIAFYCVSRDLLPFTLRLPQAILEASSFTDLETIANLGLGFWDSSLNPPQERGKPAEPPRDRAPGFPLVSSLRPTAHDANCACEIELSVGNDRLWFVNPIFIEDCSSALPTDQPPLGNCPARPLPPTSDATSPTSRWAPRRPPPPPPVLPLQPCSPAQPPVLPALAPAPACPLPTSPPVPAPHVTPHAPGPPDHPNQPPMMTCERLPCPTAGLGPLREEAMKPGAASSPLQQVPAPPLPAKKNLPTAPPRRRVSERVSLEDQSPGMAAEGDQLSLPPQGTSDGPEDTPRESTEQGQDTEVKASDPHSMPELPRTAKQPPVPPPRKKRISRQLASTLPAPLENAELCTQAMALETPTPGPPREGQSPASQAGTQHPPAQATAHSQSSPEFKGSLASLSDSLGVSVMATDQDSYSTSSTEEELEQFSSPSVKKKPSMILGKARHRLSFASFSSMFHAFLSNNRKLYKKVVELAQDKGSYFGSLVQDYKVYSLEMMARQTSSTEMLQEIRTMMTQLKSYLLQSTELKALVDPALHSEEELEAIVESALYKCVLKPLKEAINSCLHQIHSKDGSLQQLKENQLVILATTTTDLGVTTSVPEVPMMEKILQKFTSMHKAYSPEKKISILLKTCKLIYDSMALGNPGKPYGADDFLPVLMYVLARSNLTEMLLNVEYMMELMDPALQLGEGSYYLTTTYGALEHIKSYDKITVTRQLSVEVQDSIHRWERRRTLNKARASRSSVQDFICVSYLEPEQQARTLASRADTQAQALCAQCAEKFAVERPQAHRLFVLVDGRCFQLADDALPHCIKGYLLRSEPKRDFHFVYRPLDGGGGGGGGSPPCLVVREPNFL", "length": 985 }, "evidence": [ { "id": "A0AAA9TVZ2", "url": "https://omabrowser.org/oma/group/A0AAA9TVZ2/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" } ], "go_annotation": { "categories": [ { "name": "Molecular Function", "total": 3, "go_terms": [ { "name": "GTPase activator activity", "id": "GO:0005096", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005096", "evidence": [ { "database": "UniProtKB", "id": "A0AAA9TVZ2", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TVZ2" } ], "pmid": "" }, { "name": "guanyl-nucleotide exchange factor activity", "id": "GO:0005085", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005085", "evidence": [ { "database": "UniProtKB", "id": "A0AAA9TVZ2", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TVZ2" } ], "pmid": "" }, { "name": "small GTPase binding", "id": "GO:0031267", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0031267", "evidence": [ { "database": "UniProtKB", "id": "A0AAA9TVZ2", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TVZ2" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 7, "go_terms": [ { "name": "early endosome", "id": "GO:0005769", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005769", "evidence": [ { "database": "UniProtKB", "id": "A0AAA9TVZ2", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TVZ2" } ], "pmid": "" }, { "name": "axon", "id": "GO:0030424", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030424", "evidence": [ { "database": "UniProtKB", "id": "A0AAA9TVZ2", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TVZ2" } ], "pmid": "" }, { "name": "dendrite", "id": "GO:0030425", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030425", "evidence": [ { "database": "UniProtKB", "id": "A0AAA9TVZ2", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TVZ2" } ], "pmid": "" }, { "name": "neuronal cell body", "id": "GO:0043025", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0043025", "evidence": [ { "database": "UniProtKB", "id": "A0AAA9TVZ2", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TVZ2" } ], "pmid": "" }, { "name": "endocytic vesicle", "id": "GO:0030139", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030139", "evidence": [ { "database": "UniProtKB", "id": "A0AAA9TVZ2", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TVZ2" } ], "pmid": "" }, { "name": "cytoplasm", "id": "GO:0005737", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005737", "evidence": [ { "database": "UniProtKB", "id": "A0AAA9TVZ2", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TVZ2" } ], "pmid": "" }, { "name": "cytosol", "id": "GO:0005829", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005829", "evidence": [ { "database": "UniProtKB", "id": "A0AAA9TVZ2", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TVZ2" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 2, "go_terms": [ { "name": "signal transduction", "id": "GO:0007165", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007165", "evidence": [ { "database": "UniProtKB", "id": "A0AAA9TVZ2", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TVZ2" } ], "pmid": "" }, { "name": "vesicle-mediated transport", "id": "GO:0016192", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016192", "evidence": [ { "database": "UniProtKB", "id": "A0AAA9TVZ2", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TVZ2" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 107, "end_pos": 109, "annotation": "n_glycosylation_sequon" }, { "start_pos": 219, "end_pos": 221, "annotation": "n_glycosylation_sequon" }, { "start_pos": 538, "end_pos": 540, "annotation": "n_glycosylation_sequon" }, { "start_pos": 827, "end_pos": 829, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A0AAA9TVZ2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TVZ2" }, { "id": "PS50200", "database": "PROSITE", "url": "https://prosite.expasy.org/PS50200" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "Ras-associating", "eco_id": "ECO_0000259", "start_pos": 905, "end_pos": 991, "start_aa": "Gln", "end_aa": "Leu", "glycosite_overlap": [] }, { "evidence": [ { "id": "A0AAA9TVZ2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TVZ2" }, { "id": "PS50001", "database": "PROSITE", "url": "https://prosite.expasy.org/PS50001" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "SH2", "eco_id": "ECO_0000259", "start_pos": 64, "end_pos": 159, "start_aa": "Trp", "end_aa": "Arg", "glycosite_overlap": [] }, { "evidence": [ { "id": "A0AAA9TVZ2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TVZ2" }, { "id": "PS51205", "database": "PROSITE", "url": "https://prosite.expasy.org/PS51205" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "VPS9", "eco_id": "ECO_0000259", "start_pos": 731, "end_pos": 874, "start_aa": "His", "end_aa": "Thr", "glycosite_overlap": [] } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" }, { "name": "homologset.oma", "label": "OMA Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [ 206, 266, 304, 502, 520 ], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 107, "end_pos": 109 }, { "start_pos": 219, "end_pos": 221 }, { "start_pos": 538, "end_pos": 540 }, { "start_pos": 827, "end_pos": 829 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 5 }, { "field": "total_sites", "count": 5 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 5 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "exact_sites", "count": 5 }, { "field": "exact_o_linked_sites", "count": 5 }, { "field": "fuzzy_sites", "count": 0 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_pos", "start_aa", "end_pos", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 5 }, { "field": "total_sites", "count": 5 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 5 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "exact_sites", "count": 5 }, { "field": "exact_o_linked_sites", "count": 5 }, { "field": "fuzzy_sites", "count": 0 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_pos", "start_aa", "end_pos", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ], "tool_support": { "graph_view": "yes" } }, { "uniprot_canonical_ac": "A0AAA9TU63-1", "uniprot_ac": "A0AAA9TU63", "uniprot_id": "A0AAA9TU63_BOVIN", "mass": { "chemical_mass": 579088.0, "monoisotopic_mass": 579088.0 }, "refseq": {}, "gene_names": [ { "name": "UBR4", "type": "recommended", "evidence": [ { "id": "A0AAA9TU63", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TU63" } ] } ], "protein_names": [ { "name": "Ubiquitin protein ligase E3 component n-recognin 4", "type": "synonym", "evidence": [ { "id": "A0AAA9TU63", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TU63/entry#names_and_taxonomy" } ] } ], "function": [], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Bos taurus", "taxid": 9913, "evidence": [ { "database": "UniProtKB", "id": "A0AAA9TU63", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TU63" } ], "common_name": "Bovine", "glygen_name": "Bovine", "reference_species": "Bos taurus [9913]" } ], "gene": [ { "name": "UBR4", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TU63", "locus": { "chromosome": "2", "start_pos": 133589435, "end_pos": 133451900, "strand": "-", "evidence": [ { "database": "Ensembl Gene", "id": "ENSBTAG00000015240", "url": "https://www.ensembl.org/id/ENSBTAG00000015240" } ] } } ], "crossref": [ { "id": "ENSBTAG00000015240", "url": "https://bgee.org/?page=gene&gene_id=ENSBTAG00000015240", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "cd19680", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd19680", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "514561", "url": "https://www.ncbi.nlm.nih.gov/gene/514561", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR003126", "url": "https://www.ebi.ac.uk/interpro/entry/IPR003126", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR016024", "url": "https://www.ebi.ac.uk/interpro/entry/IPR016024", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR025704", "url": "https://www.ebi.ac.uk/interpro/entry/IPR025704", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR036322", "url": "https://www.ebi.ac.uk/interpro/entry/IPR036322", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR045189", "url": "https://www.ebi.ac.uk/interpro/entry/IPR045189", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR045841", "url": "https://www.ebi.ac.uk/interpro/entry/IPR045841", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR047509", "url": "https://www.ebi.ac.uk/interpro/entry/IPR047509", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR056530", "url": "https://www.ebi.ac.uk/interpro/entry/IPR056530", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "E1BHT5", "url": "https://www.orthodb.org/?gene=E1BHT5", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR21725", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR21725", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR21725:SF1", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR21725:SF1", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF02207", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF02207", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF13764", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF13764", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF19423", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF19423", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF24079", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF24079", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "R-BTA-6798695", "url": "https://www.reactome.org/PathwayBrowser/#R-BTA-6798695", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "R-BTA-983168", "url": "https://www.reactome.org/PathwayBrowser/#R-BTA-983168", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "A0AAA9TKM9", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TKM9", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0AAA9TKM9-1", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TKM9-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0AAA9TU63", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TU63", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0AAA9TU63-1", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TU63-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0AAA9TWT8", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TWT8", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0AAA9TWT8-1", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TWT8-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "E1BHT5", "url": "https://www.uniprot.org/uniprotkb/E1BHT5", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "E1BHT5-1", "url": "https://www.uniprot.org/uniprotkb/E1BHT5-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MPRPAASRPRHASLARKEGSRPPALRILAGDRVAPSDAHVASFPPPHGRRRWAGGKPPEGAAGVRRKMATSGGEEAAAVAPAVGAPAPAGDTTPGWEVAVRPLLSASYSAFEMKELPQLVASVIESESEILQHEKQYEPFYSSFVALSTHYITTVCSLIPRNQLQSVAAACKVLIEFSLLRLENPDEACAVSQKHLILLIKGLCTGCSRLDRTEIITFTAMMKSAKLPQTVKTLSDVEDQKELASPVSPELKQKEVQMNFLNQLTSVFNPRTVASSPVGPQTQAEGESEEQSSTDQASAIKTKNVFIAQNVASLQELGGSEKLLRVCLNLPYFLRYINRFQDAVLANSFFIMPATVADATAVRNGFHSLVIDVTMALDTLSLPVLEPLNPSRLQDVTVLSLSCLYAGVSVATCTAILHVGGAQQARTGCTSSKEEDHEGDAATIVQKCLEIYDMIGQAISSSRRAGGEHYQNFQLLGAWCLLNSLFLILNLSPTALADKGKEKDPLAALRVRDILSRTKEGVGSPKLGPGKGHQGFGVLSVILANHAVKLLTSLFQDLQVEALHKGWEADGPPAVLSIMAQSTSIQRIQRLIDSVPLTNLLLTLLSTSYRKACVLQRQRKGSMSSDASASTDSNTYYEDDFSSTEEDSSQDEDSEPILGQWFEETISPSKEKVAPPPPPPSPPLESSPRVKSPSKQAPGEKGNILASRKDPELFLGLASNILNFITSSMLNSRSNFIRNYLSVSLSEHHMATLASIIKEVDKDGLKGASDEEFAAALYHFNHSLVTSDLQPPNLQNTLLQQLGVAPFSEGPWPLYIHPQSLSVLSRLLLIWQHKASAQGDPDVPECLKVWDRFLSTMKQNALQGVVPAETEDLNVEHLQLLLLIFHNFSEKGRRDILTLFVQITQELSASMDAQMRSVPLILARLLLIFDYLLHQYSKAPMYLFEQVQHNLLSPPFGWASGSQDSSSRRTTTPLYHGFKEVEENWSKHFSSDAVPQPRFYCVLSPEASEDDLNRLDSVACDVLFSKLVKYDELYTALTSLLAAGSQLDTVRRKENKNVTALEACALQYYFLILWRILGILPPSKTYMNQLAMNSPEMSECDILHTLRWSSRLRISSYVNWIKDHLIKQGMKAEHAGSLLELASSKCSSVKYDVDIVEEYFARQISSFCSIDCTTILQLHEIPSLQSIYTLDAAVSKVQVSLDEHFSKVAAETDPQKSSEVTKNLLPATLQLIDTYASFTRAYLLQNFNEEGSTEKPSQEKLHGFAAVLAIGSSRCKANTLGPTLVQNLPSSVQTVCESWNNISTNEFPNIGSWRNAFANDTVPSESYISAVQAAHLGTLCGQSLPLAASLKHTLLSLVRLTGDLIVWSDEMNPPQVIRTLLPLLLESSTESVAEISSNSLERVLGPAESDEFLARVYEKLITGCYNILANHADPNSGLDESILEECLQYLEKQLESSQARKAMEDFFSDSGELVQIMMATANENLSAKFCNRVLKFFTKLFQLTEKSPNPSLLHLCGSLAQLACVEPARLQAWLTRMTASPPKDSDQLDVIQENRQLLQLLTTYIVRENSQVGEGVCAVLLGTLIPMATEMLANGDGTGFPELMVVMATLAGAGQGAGHLQLHNAAVDWLSRCKKYLSQKNVVEKLNANVMHGKHVMVLECTCHIMSYLADVTNALSQSNGQGPSHLSVDGEERAIEVDSDWVEELAVEEEDSQAEDSDEDSLCNKLCTFTITQKEFMNQHWYHCHTCKMVDGVGVCTVCAKVCHKDHEISYAKYGSFFCDCGAKEDGSCLALVKRTPSSGMSSTMKESAFQTEPRVSESLVRHTSTSPADKAKVTISDGKVADEEKPKKSSLCRTVEGCREELQNQANFSFAPLVLDMLSFLMDAIQTNFQQASAVGSSSRAQQALRELHTVDKAVEMTDQLMVPTLGSQEGAFENVRMNYSGDQGQTIRQLISAHVLRRVAMCVLSSPHGRRQHLAVSHEKGKITVLQLSALLKQADSSKRKLTLTRLASAPVPFTVLSLTGNPCKEDYLAVCGLKDCHVLTFSSSGSVSDHLVLHPQLATGNFIIKAVWLPGSQTELAIVTADFVKVYDLSVDALSPAFYFLLPSSKIRDVTFLFNEEGKNIIVIMSSAGYIYTQLMEEASSAQQGPFYVTNVLEVNHEDLKDSNSQVAGGGVSVYYSHVLQMLFFSYCQGRSFAATVSRTTLEVLQLFSINIKSPNGGSKAPPALCQWSEVMNHPGLVCCVQQTTGVPLVVMVKPDTFLIQEIKTLPAKAKIQDMVAIRHTACNEQQRTTMILLCEDGSLRIYMANVENTSYWLQPSLQPSSVISIMKPVRKRKTATITARTSSQVAFPIDFFEHNQQLSDVEFGGNDLLQVYNAQQIKHRLNSTGMYVANTKPGGFTIEISNNNSTMVMTGMRIQIGTQAIERAPSYIEIFGRTMQLNLSRSRWFDFPFTREEALQADKKLNLFIGASVDPAGVTMIDAVKIYGKTKEQFGWPDEPPEEFPAASVSNICPSNLTQSNGTGDSDSAAPAVTGGTVLERLVVSSLEALESCFAVGPIIEKERNKNAAQELATLLLSLPAPASVQQQSKSLLASLHTSRSAYHSHKDQALLSKAVQCLNTSSKEGKDLDPEVFQRLVVTARSIAVTRPNNLVHFTESRLPQTETEGADEGREPQKQLEGDSCSFITQLVNHFWKLHASKPKNAFLAPACLPGLTHIEATVNALVDIIHGYCTCELDCINTASRIYMQMLLCPDPAVSFSCKQALIRVLRPRNKRRHVTLPSSPRSNTPMGDKDDDDDDDADEKMQSSGIPNGGHIRQESQEQSEVDHGDFEMVSESMVLETAENVNNGNPSPLEALLAGAEGFPPMLDIPPDADDETMVELAIALSLQQDQQGSSSSALGLQSLGLSGQAPSSSSLDAGTLSDTTASAPASDDEGSTAATDGSTLRTSPADHGGSVGSESGGSAVDSVAGEHSVSGRSSAYGDATAEGHPAGPGSVSSSTGAISTTTGHQEGDGSEGEGEGDGEADVHASNRLHMVRLMLLERLLQTLPQLRSVGGVRAIPYMQVILMLTTDLDGEDEKDKGALDNLLSQLIAELGMDKKDVSRKSERSALNEVHLVLMRLLSVFMSRTKSGSKASVCESSSLISSATAAALLSSGAVDYCLHVLKSLLEHWKSQQSDEEPVATSQLLKPHTTSSPPDMSPFFLRQYVKGHAADVFEAYTQLLTEMVLRLPYQIKKIADTNSRIPPPVFDHSWFYFLSEYLMIQQTPFVRRQVRKLLLFICGSKEKYRQLRDLHTLDSHVRGIKKLLEEQGIFLRASVVTASSGSALQYDTLISLMEHLKACAEIAAQRTVNWQRFCIKDDSVLYFLLQVSFLVDEGVSPVLLQLLSCALCGSKVLAALAASAGSSSTSSSSAPAAASSGQATAQPKSSTKKSKKEEKEKEKEGESSGSQEDQLCTALVNQLNKFADKETLVQFLRCFLLESNSSSVRWQAHCLTLHIYRNSSKSQQELLLDLMWSIWPELAAYGRKAAQFVDLLGYFSLKTPQTEKKLKEYSQKAVEILRTQNHILTNHPNSNIYNALSGLVEFDGCYLESGPCLVCNNPEVPLCYIKLSSIKVDTRYTTTQQVVKLIGSHTISKVTVKIGDLKRTKMVRTINLYYNNRTVQAIVELKNKPARWHKAKKVQLTPGQTEVKIDLPLPIVASNLMIEFADFYENYQASTETLQCPRCSASVPANPGVCGNCGENVYQCHKCRSINYDEKDPFLCNACGFCKYARFDFMLYAKPCCAVDPIENEEDRKKAVSNINTLLDKADRVYHQLMGHRPQLENLLCKVNEAAPEKPQDDSGTSGGISSTSASVNRYILQLAQEYCGDCKSSFDELSKIIQKVFASRKELLEYDLQQREAATKSSRTSVQPTFTASQYRALSVLGCGHTSSTKCYGCASAVTEHCITLLRALATNPALRHILVSQGLIRELFDYNLRRGSAAMREEVRQLMCLLTRDNPEATQQMNDLIIGKVSTALKGHWANPDLASSLQYEMLLLTDSISKEDSCWELRLRCALSLFLMAVNIKTPVVVENITLMCLRILQKLIKPPAPTSKKNKDVPVEALTTVRPYCNEIHAQAQLWLKRDPKASYDAWKKCLPIRGVDGNGKSPSKAELRHLYLTEKYVWRWKQFLSRRGKRTPPLDLQLGHNNWLRQVLFTPATQAARQAACTIVEALATIPSRKQQVLDLLTSYLDELSVAGECAAEYLALYQKLITSAHWKVYLAARGVLPYVGNLITKEIARLLALEEATLSTDLQQGYALKSLTGLLSSFVEVESIKRHFKSRLVGTVLNGYLCLRKLVVQRTKLIDETQDMLLEMLEDMTTGTESETKAFMAVCIETAKRYNLDDSRTPVFIFERLCSIIYPEENEVTEFFVTLEKDPQQEDFLQGRMPGNPYSSNEPGIGPLMRDIKNKICQDCDLVALLEDDSGMELLVNNKIISLDLPVAEVYKKVWCTTNEGEPMRIVYRMRGLLGDATEEFIESLDSTTDEEEDEEEVYKMAGVMAQCGGLECMLNRLAGIKDFKQGRHLLTVLLKLFSYCVKVKVNRQQLVKLEMNTLNVMLGTLNLALVAEQESKDSGGAAVAEQVLSIMEIILDESNAEPLSEDKGNLLLTGDKDQLVMLLDQINSTFVRSNPSVLQGLLRIIPYLSFGEVEKMQILVERFKPYCSFDKYDEDHSGDDKVFLDCFCKIAAGIKNNSNGHQLKDLILQKGITQSALDYMKKHIPSAKNLDADIWKKFLSRPALPFILRLLRGLAIQHPATQVLIGTDSITNLHKLEQVSSDEGIGTLAENLLEALREHPDVNKKIDAARRETRAEKKRMAMAMRQKALGTLGMTTNEKGQVVTKTALLKQMEELIEEPGLTCCICREGYKFQPTKVLGIYTFTKRVALEEMESKPRKQQGYSTVSHFNIVHYDCHLAAVRLARGREEWESAALQNANTKCNGLLPVWGPHVPESAFATCLARHNTYLQECTGQREPTYQLNIHDIKLLFLRFAMEQSFSADTGGGGRESNIHLIPYIVHTVLYVLNTTRATSREEKNLQGFLEQPKEKWVESAFEVDGPHYFTVLALHVLPPEKWRAVRVEILRRLLVTSQARAVSPGGATRLTDKALKDYSAYRSSLLFWALVDLIYNMFKKVPTSNTEGGWSCSLAEYIRHNDMPIHEAADKALKAFQEEFMPAETFSEFLDAAGLLSEVTDAESFLKDLLNSVP", "length": 5248, "header": "tr|A0AAA9TU63-1|A0AAA9TU63_BOVIN Isoform 1 of Ubiquitin protein ligase E3 component n-recognin 4 OS=Bos taurus OX=9913 GN=UBR4 PE=3 SV=1 CANONICAL=A0AAA9TU63-1" }, "isoforms": [ { "isoform_ac": "A0AAA9TKM9-1", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TKM9/entry", "sequence": { "sequence": "MPRPAASRPRHASLARKEGSRPPALRILAGDRVAPSDAHVASFPPPHGRRRWAGGKPPEGAAGVRRKMATSGGEEAAAVAPAVGAPAPAGDTTPGWEVAVRPLLSASYSAFEMKELPQLVASVIESESEILQHEKQYEPFYSSFVALSTHYITTVCSLIPRNQLQSVAAACKVLIEFSLLRLENPDEACAVSQKHLILLIKGLCTGCSRLDRTEIITFTAMMKSAKLPQTVKTLSDVEDQKELASPVSPELKQKEVQMNFLNQLTSVFNPRTVASSPVGPQTQAEGESEEQSSTDQASAIKTKNVFIAQNVASLQELGGSEKLLRVCLNLPYFLRYINRFQDAVLANSFFIMPATVADATAVRNGFHSLVIDVTMALDTLSLPVLEPLNPSRLQDVTVLSLSCLYAGVSVATCTAILHVGGAQQARTGCTSSKEEDHEGDAATIVQKCLEIYDMIGQAISSSRRAGGEHYQNFQLLGAWCLLNSLFLILNLSPTALADKGKEKDPLAALRVRDILSRTKEGVGSPKLGPGKGHQGFGVLSVILANHAVKLLTSLFQDLQVEALHKGWEADGPPAVLSIMAQSTSIQRIQRLIDSVPLTNLLLTLLSTSYRKACVLQRQRKGSMSSDASASTDSNTYYEDDFSSTEEDSSQDEDSEPILGQWFEETISPSKEKVAPPPPPPSPPLESSPRVKSPSKQAPGEKGNILASRKDPELFLGLASNILNFITSSMLNSRSNFIRNYLSVSLSEHHMATLASIIKEVDKDGLKGASDEEFAAALYHFNHSLVTSDLQPPNLQNTLLQQLGVAPFSEGPWPLYIHPQSLSVLSRLLLIWQHKASAQGDPDVPECLKVWDRFLSTMKQNALQGVVPAETEDLNVEHLQLLLLIFHNFSEKGRRDILTLFVQITQELSASMDAQMRSVPLILARLLLIFDYLLHQYSKAPMYLFEQVQHNLLSPPFGWASGSQDSSSRRTTTPLYHGFKEVEENWSKHFSSDAVPQPRFYCVLSPEASEDDLNRLDSVACDVLFSKLVKYDELYTALTSLLAAGSQLDTVRRKENKNVTALEACALQYYFLILWRILGILPPSKTYMNQLAMNSPEMSECDILHTLRWSSRLRISSYVNWIKDHLIKQGMKAEHAGSLLELASSKCSSVKYDVDIVEEYFARQISSFCSIDCTTILQLHEIPSLQSIYTLDAAVSKVQVSLDEHFSKVAAETDPQKSSEVTKNLLPATLQLIDTYASFTRAYLLQNFNEEGSTEKPSQEKLHGFAAVLAIGSSRCKANTLGPTLVQNLPSSVQTVCESWNNISTNEFPNIGSWRNAFANDTVPSESYISAVQAAHLGTLCGQSLPLAASLKHTLLSLVRLTGDLIVWSDEMNPPQVIRTLLPLLLESSTESVAEISSNSLERVLGPAESDEFLARVYEKLITGCYNILANHADPNSGLDESILEECLQYLEKQLESSQARKAMEDFFSDSGELVQIMMATANENLSAKFCNRVLKFFTKLFQLTEKSPNPSLLHLCGSLAQLACVEPARLQAWLTRMTASPPKDSDQLDVIQENRQLLQLLTTYIVRENSQVGEGVCAVLLGTLIPMATEMLANGDGTGFPELMVVMATLAGAGQGAGHLQLHNAAVDWLSRCKKYLSQKNVVEKLNANVMHGKHVMVLECTCHIMSYLADVTNALSQSNGQGPSHLSVDGEERAIEVDSDWVEELAVEEEDSQAEDSDEDSLCNKLCTFTITQKEFMNQHWYHCHTCKMVDGVGVCTVCAKVCHKDHEISYAKYGSFFCDCGAKEDGSCLALVKRTPSSGMSSTMKESAFQTEPRVSESLVRHTSTSPADKAKVTISDGKVADEEKPKKSSLCRTVEGCREELQNQANFSFAPLVLDMLSFLMDAIQTNFQQASAVGSSSRAQQALRELHTVDKAVEMTDQLMVPTLGSQEGAFENVRMNYSGDQGQTIRQLISAHVLRRVAMCVLSSPHGRRQHLAVSHEKGKITVLQLSALLKQADSSKRKLTLTRLASAPVPFTVLSLTGNPCKEDYLAVCGLKDCHVLTFSSSGSVSDHLVLHPQLATGNFIIKAVWLPGSQTELAIVTADFVKVYDLSVDALSPAFYFLLPSSKIRDVTFLFNEEGKNIIVIMSSAGYIYTQLMEEASSAQQGPFYVTNVLEVNHEDLKDSNSQVAGGGVSVYYSHVLQMLFFSYCQGRSFAATVSRTTLEVLQLFSINIKSPNGGSKAPPALCQWSEVMNHPGLVCCVQQTTGVPLVVMVKPDTFLIQEIKTLPAKAKIQDMVAIRHTACNEQQRTTMILLCEDGSLRIYMANVENTSYWLQPSLQPSSVISIMKPVRKRKTATITARTSSQVAFPIDFFEHNQQLSDVEFGGNDLLQVYNAQQIKHRLNSTGMYVANTKPGGFTIEISNNNSTMVMTGMRIQIGTQAIERAPSYIEIFGRTMQLNLSRSRWFDFPFTREEALQADKKLNLFIGASVDPAGVTMIDAVKIYGKTKEQFGWPDEPPEEFPAASVSNICPSNLTQSNGTGDSDSAAPAVTGGTVLERLVVSSLEALESCFAVGPIIEKERNKNAAQELATLLLSLPAPASVQQQSKSLLASLHTSRSAYHSHKDQALLSKAVQCLNTSSKEGKDLDPEVFQRLVVTARSIAVTRPNNLVHFTESRLPQTETEGADEGREPQKQLEGDSCSFITQLVNHFWKLHASKPKNAFLAPACLPGLTHIEATVNALVDIIHGYCTCELDCINTASRIYMQMLLCPDPAVSFSCKQALIRVLRPRNKRRHVTLPSSPRSNTPMGDKDDDDDDDADEKMQSSGIPNGGHIRQESQEQSEVDHGDFEMVSESMVLETAENVNNGNPSPLEALLAGAEGFPPMLDIPPDADDETMVELAIALSLQQDQQAPASDDEGSTAATDGSTLRTSPADHGGSVGSESGGSAVDSVAGEHSVSGRSSAYGDATAEGHPAGPGSVSSSTGAISTTTGHQEGDGSEGEGEGDGEADVHASNRLHMVRLMLLERLLQTLPQLRSVGGVRAIPYMQVILMLTTDLDGEDEKDKGALDNLLSQLIAELGMDKKDVSRKSERSALNEVHLVLMRLLSVFMSRTKSGSKASVCESSSLISSATAAALLSSGAVDYCLHVLKSLLEHWKSQQSDEEPVATSQLLKPHTTSSPPDMSPFFLRQYVKGHAADVFEAYTQLLTEMVLRLPYQIKKIADTNSRIPPPVFDHSWFYFLSEYLMIQQTPFVRRQVRKLLLFICGSKEKYRQLRDLHTLDSHVRGIKKLLEEQGIFLRASVVTASSGSALQYDTLISLMEHLKACAEIAAQRTVNWQRFCIKDDSVLYFLLQVSFLVDEGVSPVLLQLLSCALCGSKVLAALAASAGSSSTSSSSAPAAASSGQATAQPKSSTKKSKKEEKEKEKEGESSGSQEDQLCTALVNQLNKFADKETLVQFLRCFLLESNSSSVRWQAHCLTLHIYRNSSKSQQELLLDLMWSIWPELAAYGRKAAQFVDLLGYFSLKTPQTEKKLKEYSQKAVEILRTQNHILTNHPNSNIYNALSGLVEFDGCYLESGPCLVCNNPEVPLCYIKLSSIKVDTRYTTTQQVVKLIGSHTISKVTVKIGDLKRTKMVRTINLYYNNRTVQAIVELKNKPARWHKAKKVQLTPGQTEVKIDLPLPIVASNLMIEFADFYENYQASTETLQCPRCSASVPANPGVCGNCGENVYQCHKCRSINYDEKDPFLCNACGFCKYARFDFMLYAKPCCAVDPIENEEDRKKAVSNINTLLDKADRVYHQLMGHRPQLENLLCKVNEAAPEKPQDDSGTSGGISSTSASVNRYILQLAQEYCGDCKSSFDELSKIIQKVFASRKELLEYDLQQREAATKSSRTSVQPTFTASQYRALSVLGCGHTSSTKCYGCASAVTEHCITLLRALATNPALRHILVSQGLIRELFDYNLRRGSAAMREEVRQLMCLLTRDNPEATQQMNDLIIGKVSTALKGHWANPDLASSLQYEMLLLTDSISKEDSCWELRLRCALSLFLMAVNIKTPVVVENITLMCLRILQKLIKPPAPTSKKNKDVPVEALTTVRPYCNEIHAQAQLWLKRDPKASYDAWKKCLPIRGVDGNGKSPSKAELRHLYLTEKYVWRWKQFLSRRGKRTPPLDLQLGHNNWLRQVLFTPATQAARQAACTIVEALATIPSRKQQVLDLLTSYLDELSVAGECAAEYLALYQKLITSAHWKVYLAARGVLPYVGNLITKEIARLLALEEATLSTDLQQGYALKSLTGLLSSFVEVESIKRHFKSRLVGTVLNGYLCLRKLVVQRTKLIDETQDMLLEMLEDMTTGTESETKAFMAVCIETAKRYNLDDSRTPVFIFERLCSIIYPEENEVTEFFVTLEKDPQQEDFLQGRMPGNPYSSNEPGIGPLMRDIKNKICQDCDLVALLEDDSGMELLVNNKIISLDLPVAEVYKKVWCTTNEGEPMRIVYRMRGLLGDATEEFIESLDSTTDEEEDEEEVYKMAGVMAQCGGLECMLNRLAGIKDFKQGRHLLTVLLKLFSYCVKVKVNRQQLVKLEMNTLNVMLGTLNLALVAEQESKDSGGAAVAEQVLSIMEIILDESNAEPLSEDKGNLLLTGDKDQLVMLLDQINSTFVRSNPSVLQGLLRIIPYLSFGEVEKMQILVERFKPYCSFDKYDEDHSGDDKVFLDCFCKIAAGIKNNSNGHQLKDLILQKGITQSALDYMKKHIPSAKNLDADIWKKFLSRPALPFILRLLRGLAIQHPATQVLIGTDSITNLHKLEQVSSDEGIGTLAENLLEALREHPDVNKKIDAARRETRAEKKRMAMAMRQKALGTLGMTTNEKGQVVTKTALLKQMEELIEEPGLTCCICREGYKFQPTKVLGIYTFTKRVALEEMESKPRKQQGYSTVSHFNIVHYDCHLAAVRLARGREEWESAALQNANTKCNGLLPVWGPHVPESAFATCLARHNTYLQECTGQREPTYQLNIHDIKLLFLRFAMEQSFSADTGGGGRESNIHLIPYIVHTVLYVLNTTRATSREEKNLQGFLEQPKEKWVESAFEVDGPHYFTVLALHVLPPEKWRAVRVEILRRLLVTSQARAVSPGGATRLTDKALKDYSAYRSSLLFWALVDLIYNMFKKVPTSNTEGGWSCSLAEYIRHNDMPIHEAADKALKAFQEEFMPAETFSEFLDAAGLLSEVTDAESFLKDLLNSVP", "length": 5213, "header": "tr|A0AAA9TKM9-1|A0AAA9TU63_BOVIN Computationally mapped isoform of Ubiquitin protein ligase E3 component n-recognin 4 OS=Bos taurus OX=9913 GN=UBR4 PE=3 SV=1 CANONICAL=A0AAA9TU63-1" }, "locus": { "chromosome": "2", "start_pos": 133588979, "end_pos": 133451942, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000104123.1", "url": "https://www.ensembl.org/id/ENSBTAT00000104123.1" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000097746.1", "url": "https://www.ensembl.org/id/ENSBTAP00000097746.1" } ] } }, { "isoform_ac": "A0AAA9TU63-1", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TU63/entry", "sequence": { "sequence": "MPRPAASRPRHASLARKEGSRPPALRILAGDRVAPSDAHVASFPPPHGRRRWAGGKPPEGAAGVRRKMATSGGEEAAAVAPAVGAPAPAGDTTPGWEVAVRPLLSASYSAFEMKELPQLVASVIESESEILQHEKQYEPFYSSFVALSTHYITTVCSLIPRNQLQSVAAACKVLIEFSLLRLENPDEACAVSQKHLILLIKGLCTGCSRLDRTEIITFTAMMKSAKLPQTVKTLSDVEDQKELASPVSPELKQKEVQMNFLNQLTSVFNPRTVASSPVGPQTQAEGESEEQSSTDQASAIKTKNVFIAQNVASLQELGGSEKLLRVCLNLPYFLRYINRFQDAVLANSFFIMPATVADATAVRNGFHSLVIDVTMALDTLSLPVLEPLNPSRLQDVTVLSLSCLYAGVSVATCTAILHVGGAQQARTGCTSSKEEDHEGDAATIVQKCLEIYDMIGQAISSSRRAGGEHYQNFQLLGAWCLLNSLFLILNLSPTALADKGKEKDPLAALRVRDILSRTKEGVGSPKLGPGKGHQGFGVLSVILANHAVKLLTSLFQDLQVEALHKGWEADGPPAVLSIMAQSTSIQRIQRLIDSVPLTNLLLTLLSTSYRKACVLQRQRKGSMSSDASASTDSNTYYEDDFSSTEEDSSQDEDSEPILGQWFEETISPSKEKVAPPPPPPSPPLESSPRVKSPSKQAPGEKGNILASRKDPELFLGLASNILNFITSSMLNSRSNFIRNYLSVSLSEHHMATLASIIKEVDKDGLKGASDEEFAAALYHFNHSLVTSDLQPPNLQNTLLQQLGVAPFSEGPWPLYIHPQSLSVLSRLLLIWQHKASAQGDPDVPECLKVWDRFLSTMKQNALQGVVPAETEDLNVEHLQLLLLIFHNFSEKGRRDILTLFVQITQELSASMDAQMRSVPLILARLLLIFDYLLHQYSKAPMYLFEQVQHNLLSPPFGWASGSQDSSSRRTTTPLYHGFKEVEENWSKHFSSDAVPQPRFYCVLSPEASEDDLNRLDSVACDVLFSKLVKYDELYTALTSLLAAGSQLDTVRRKENKNVTALEACALQYYFLILWRILGILPPSKTYMNQLAMNSPEMSECDILHTLRWSSRLRISSYVNWIKDHLIKQGMKAEHAGSLLELASSKCSSVKYDVDIVEEYFARQISSFCSIDCTTILQLHEIPSLQSIYTLDAAVSKVQVSLDEHFSKVAAETDPQKSSEVTKNLLPATLQLIDTYASFTRAYLLQNFNEEGSTEKPSQEKLHGFAAVLAIGSSRCKANTLGPTLVQNLPSSVQTVCESWNNISTNEFPNIGSWRNAFANDTVPSESYISAVQAAHLGTLCGQSLPLAASLKHTLLSLVRLTGDLIVWSDEMNPPQVIRTLLPLLLESSTESVAEISSNSLERVLGPAESDEFLARVYEKLITGCYNILANHADPNSGLDESILEECLQYLEKQLESSQARKAMEDFFSDSGELVQIMMATANENLSAKFCNRVLKFFTKLFQLTEKSPNPSLLHLCGSLAQLACVEPARLQAWLTRMTASPPKDSDQLDVIQENRQLLQLLTTYIVRENSQVGEGVCAVLLGTLIPMATEMLANGDGTGFPELMVVMATLAGAGQGAGHLQLHNAAVDWLSRCKKYLSQKNVVEKLNANVMHGKHVMVLECTCHIMSYLADVTNALSQSNGQGPSHLSVDGEERAIEVDSDWVEELAVEEEDSQAEDSDEDSLCNKLCTFTITQKEFMNQHWYHCHTCKMVDGVGVCTVCAKVCHKDHEISYAKYGSFFCDCGAKEDGSCLALVKRTPSSGMSSTMKESAFQTEPRVSESLVRHTSTSPADKAKVTISDGKVADEEKPKKSSLCRTVEGCREELQNQANFSFAPLVLDMLSFLMDAIQTNFQQASAVGSSSRAQQALRELHTVDKAVEMTDQLMVPTLGSQEGAFENVRMNYSGDQGQTIRQLISAHVLRRVAMCVLSSPHGRRQHLAVSHEKGKITVLQLSALLKQADSSKRKLTLTRLASAPVPFTVLSLTGNPCKEDYLAVCGLKDCHVLTFSSSGSVSDHLVLHPQLATGNFIIKAVWLPGSQTELAIVTADFVKVYDLSVDALSPAFYFLLPSSKIRDVTFLFNEEGKNIIVIMSSAGYIYTQLMEEASSAQQGPFYVTNVLEVNHEDLKDSNSQVAGGGVSVYYSHVLQMLFFSYCQGRSFAATVSRTTLEVLQLFSINIKSPNGGSKAPPALCQWSEVMNHPGLVCCVQQTTGVPLVVMVKPDTFLIQEIKTLPAKAKIQDMVAIRHTACNEQQRTTMILLCEDGSLRIYMANVENTSYWLQPSLQPSSVISIMKPVRKRKTATITARTSSQVAFPIDFFEHNQQLSDVEFGGNDLLQVYNAQQIKHRLNSTGMYVANTKPGGFTIEISNNNSTMVMTGMRIQIGTQAIERAPSYIEIFGRTMQLNLSRSRWFDFPFTREEALQADKKLNLFIGASVDPAGVTMIDAVKIYGKTKEQFGWPDEPPEEFPAASVSNICPSNLTQSNGTGDSDSAAPAVTGGTVLERLVVSSLEALESCFAVGPIIEKERNKNAAQELATLLLSLPAPASVQQQSKSLLASLHTSRSAYHSHKDQALLSKAVQCLNTSSKEGKDLDPEVFQRLVVTARSIAVTRPNNLVHFTESRLPQTETEGADEGREPQKQLEGDSCSFITQLVNHFWKLHASKPKNAFLAPACLPGLTHIEATVNALVDIIHGYCTCELDCINTASRIYMQMLLCPDPAVSFSCKQALIRVLRPRNKRRHVTLPSSPRSNTPMGDKDDDDDDDADEKMQSSGIPNGGHIRQESQEQSEVDHGDFEMVSESMVLETAENVNNGNPSPLEALLAGAEGFPPMLDIPPDADDETMVELAIALSLQQDQQGSSSSALGLQSLGLSGQAPSSSSLDAGTLSDTTASAPASDDEGSTAATDGSTLRTSPADHGGSVGSESGGSAVDSVAGEHSVSGRSSAYGDATAEGHPAGPGSVSSSTGAISTTTGHQEGDGSEGEGEGDGEADVHASNRLHMVRLMLLERLLQTLPQLRSVGGVRAIPYMQVILMLTTDLDGEDEKDKGALDNLLSQLIAELGMDKKDVSRKSERSALNEVHLVLMRLLSVFMSRTKSGSKASVCESSSLISSATAAALLSSGAVDYCLHVLKSLLEHWKSQQSDEEPVATSQLLKPHTTSSPPDMSPFFLRQYVKGHAADVFEAYTQLLTEMVLRLPYQIKKIADTNSRIPPPVFDHSWFYFLSEYLMIQQTPFVRRQVRKLLLFICGSKEKYRQLRDLHTLDSHVRGIKKLLEEQGIFLRASVVTASSGSALQYDTLISLMEHLKACAEIAAQRTVNWQRFCIKDDSVLYFLLQVSFLVDEGVSPVLLQLLSCALCGSKVLAALAASAGSSSTSSSSAPAAASSGQATAQPKSSTKKSKKEEKEKEKEGESSGSQEDQLCTALVNQLNKFADKETLVQFLRCFLLESNSSSVRWQAHCLTLHIYRNSSKSQQELLLDLMWSIWPELAAYGRKAAQFVDLLGYFSLKTPQTEKKLKEYSQKAVEILRTQNHILTNHPNSNIYNALSGLVEFDGCYLESGPCLVCNNPEVPLCYIKLSSIKVDTRYTTTQQVVKLIGSHTISKVTVKIGDLKRTKMVRTINLYYNNRTVQAIVELKNKPARWHKAKKVQLTPGQTEVKIDLPLPIVASNLMIEFADFYENYQASTETLQCPRCSASVPANPGVCGNCGENVYQCHKCRSINYDEKDPFLCNACGFCKYARFDFMLYAKPCCAVDPIENEEDRKKAVSNINTLLDKADRVYHQLMGHRPQLENLLCKVNEAAPEKPQDDSGTSGGISSTSASVNRYILQLAQEYCGDCKSSFDELSKIIQKVFASRKELLEYDLQQREAATKSSRTSVQPTFTASQYRALSVLGCGHTSSTKCYGCASAVTEHCITLLRALATNPALRHILVSQGLIRELFDYNLRRGSAAMREEVRQLMCLLTRDNPEATQQMNDLIIGKVSTALKGHWANPDLASSLQYEMLLLTDSISKEDSCWELRLRCALSLFLMAVNIKTPVVVENITLMCLRILQKLIKPPAPTSKKNKDVPVEALTTVRPYCNEIHAQAQLWLKRDPKASYDAWKKCLPIRGVDGNGKSPSKAELRHLYLTEKYVWRWKQFLSRRGKRTPPLDLQLGHNNWLRQVLFTPATQAARQAACTIVEALATIPSRKQQVLDLLTSYLDELSVAGECAAEYLALYQKLITSAHWKVYLAARGVLPYVGNLITKEIARLLALEEATLSTDLQQGYALKSLTGLLSSFVEVESIKRHFKSRLVGTVLNGYLCLRKLVVQRTKLIDETQDMLLEMLEDMTTGTESETKAFMAVCIETAKRYNLDDSRTPVFIFERLCSIIYPEENEVTEFFVTLEKDPQQEDFLQGRMPGNPYSSNEPGIGPLMRDIKNKICQDCDLVALLEDDSGMELLVNNKIISLDLPVAEVYKKVWCTTNEGEPMRIVYRMRGLLGDATEEFIESLDSTTDEEEDEEEVYKMAGVMAQCGGLECMLNRLAGIKDFKQGRHLLTVLLKLFSYCVKVKVNRQQLVKLEMNTLNVMLGTLNLALVAEQESKDSGGAAVAEQVLSIMEIILDESNAEPLSEDKGNLLLTGDKDQLVMLLDQINSTFVRSNPSVLQGLLRIIPYLSFGEVEKMQILVERFKPYCSFDKYDEDHSGDDKVFLDCFCKIAAGIKNNSNGHQLKDLILQKGITQSALDYMKKHIPSAKNLDADIWKKFLSRPALPFILRLLRGLAIQHPATQVLIGTDSITNLHKLEQVSSDEGIGTLAENLLEALREHPDVNKKIDAARRETRAEKKRMAMAMRQKALGTLGMTTNEKGQVVTKTALLKQMEELIEEPGLTCCICREGYKFQPTKVLGIYTFTKRVALEEMESKPRKQQGYSTVSHFNIVHYDCHLAAVRLARGREEWESAALQNANTKCNGLLPVWGPHVPESAFATCLARHNTYLQECTGQREPTYQLNIHDIKLLFLRFAMEQSFSADTGGGGRESNIHLIPYIVHTVLYVLNTTRATSREEKNLQGFLEQPKEKWVESAFEVDGPHYFTVLALHVLPPEKWRAVRVEILRRLLVTSQARAVSPGGATRLTDKALKDYSAYRSSLLFWALVDLIYNMFKKVPTSNTEGGWSCSLAEYIRHNDMPIHEAADKALKAFQEEFMPAETFSEFLDAAGLLSEVTDAESFLKDLLNSVP", "length": 5248, "header": "tr|A0AAA9TU63-1|A0AAA9TU63_BOVIN Isoform 1 of Ubiquitin protein ligase E3 component n-recognin 4 OS=Bos taurus OX=9913 GN=UBR4 PE=3 SV=1 CANONICAL=A0AAA9TU63-1" }, "locus": { "chromosome": "2", "start_pos": 133588979, "end_pos": 133451942, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000133057.1", "url": "https://www.ensembl.org/id/ENSBTAT00000133057.1" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000101912.1", "url": "https://www.ensembl.org/id/ENSBTAP00000101912.1" } ] } }, { "isoform_ac": "A0AAA9TWT8-1", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TWT8/entry", "sequence": { "sequence": "MKELPQLVASVIESESEILQHEKQYEPFYSSFVALSTHYITTVCSLIPRNQLQSVAAACKVLIEFSLLRLENPDEACAVSQKHLILLIKGLCTGCSRLDRTEIITFTAMMKSAKLPQTVKTLSDVEDQKELASPVSPELKQKEVQMNFLNQLTSVFNPRTVASSPVGPQTQAEGESEEQSSTDQASAIKTKNVFIAQNVASLQELGGSEKLLRVCLNLPYFLRYINRFQDAVLANSFFIMPATVADATAVRNGFHSLVIDVTMALDTLSLPVLEPLNPSRLQDVTVLSLSCLYAGVSVATCTAILHVGGAQQARTGCTSSKEEDHEGDAATIVQKCLEIYDMIGQAISSSRRAGGEHYQNFQLLGAWCLLNSLFLILNLSPTALADKGKEKDPLAALRVRDILSRTKEGVGSPKLGPGKGHQGFGVLSVILANHAVKLLTSLFQDLQVEALHKGWEADGPPAVLSIMAQSTSIQRIQRLIDSVPLTNLLLTLLSTSYRKACVLQRQRKGSMSSDASASTDSNTYYEDDFSSTEEDSSQDEDSEPILGQWFEETISPSKEKVAPPPPPPSPPLESSPRVKSPSKQAPGEKGNILASRKDPELFLGLASNILNFITSSMLNSRSNFIRNYLSVSLSEHHMATLASIIKEVDKDGLKGASDEEFAAALYHFNHSLVTSDLQPPNLQVQHNLLSPPFGWASGSQDSSSRRTTTPLYHGFKEVEENWSKHFSSDAVPQPRFYCVLSPEASEDDLNRLDSVACDVLFSKLVKYDELYTALTSLLAAGSQLDTVRRKENKNVTALEACALQYYFLILWRILGILPPSKTYMNQLAMNSPEMSECDILHTLRWSSRLRISSYVNWIKDHLIKQGMKAEHAGSLLELASSKCSSVKYDVDIVEEYFARQISSFCSIDCTTILQLHEIPSLQSIYTLDAAVSKVQVSLDEHFSKVAAETDPQKSSEVTKNLLPATLQLIDTYASFTRAYLLQNFNEEGSTEKPSQEKLHGFAAVLAIGSSRCKANTLGPTLVQNLPSSVQTVCESWNNISTNEFPNIGSWRNAFANDTVPSESYISAVQAAHLGTLCGQSLPLAASLKHTLLSLVRLTGDLIVWSDEMNPPQVIRTLLPLLLESSTESVAEISSNSLERVLGPAESDEFLARVYEKLITGCYNILANHADPNSGLDESILEECLQYLEKQLESSQARKAMEDFFSDSGELVQIMMATANENLSAKFCNRVLKFFTKLFQLTEKSPNPSLLHLCGSLAQLACVEPARLQAWLTRMTASPPKDSDQLDVIQENRQLLQLLTTYIVRENSQVGEGVCAVLLGTLIPMATEMLANGDGTGFPELMVVMATLAGAGQGAGHLQLHNAAVDWLSRCKKYLSQKNVVEKLNANVMHGKHVMVLECTCHIMSYLADVTNALSQSNGQGPSHLSVDGEERAIEVDSDWVEELAVEEEDSQAEDSDEDSLCNKLCTFTITQKEFMNQHWYHCHTCKMVDGVGVCTVCAKVCHKDHEISYAKYGSFFCDCGAKEDGSCLALVKRTPSSGMSSTMKESAFQTEPRVSESLVRHTSTSPADKAKVTISDGKVADEEKPKKSSLCRTVEGCREELQNQANFSFAPLVLDMLSFLMDAIQTNFQQASAVGSSSRAQQALRELHTVDKAVEMTDQLMVPTLGSQEGAFENVRMNYSGDQGQTIRQLISAHVLRRVAMCVLSSPHGRRQHLAVSHEKGKITVLQLSALLKQADSSKRKLTLTRLASAPVPFTVLSLTGNPCKEDYLAVCGLKDCHVLTFSSSGSVSDHLVLHPQLATGNFIIKAVWLPGSQTELAIVTADFVKVYDLSVDALSPAFYFLLPSSKIRDVTFLFNEEGKNIIVIMSSAGYIYTQLMEEASSAQQGPFYVTNVLEVNHEDLKDSNSQVAGGGVSVYYSHVLQMLFFSYCQGRSFAATVSRTTLEVLQLFSINIKSPNGGSKAPPALCQWSEVMNHPGLVCCVQQTTGVPLVVMVKPDTFLIQEIKTLPAKAKIQDMVAIRHTACNEQQRTTMILLCEDGSLRIYMANVENTSYWLQPSLQPSSVISIMKPVRKRKTATITARTSSQVAFPIDFFEHNQQLSDVEFGGNDLLQVYNAQQIKHRLNSTGMYVANTKPGGFTIEISNNNSTMVMTGMRIQIGTQAIERAPSYIEIFGRTMQLNLSRSRWFDFPFTREEALQADKKLNLFIGASVDPAGVTMIDAVKIYGKTKEQFGWPDEPPEEFPAASVSNICPSNLTQSNGTGDSDSAAPAVTGGTVLERLVVSSLEALESCFAVGPIIEKERNKNAAQELATLLLSLPAPASVQQQSKSLLASLHTSRSAYHSHKDQALLSKAVQCLNTSSKEGKDLDPEVFQRLVVTARSIAVTRPNNLVHFTESRLPQTETEGADEGREPQKQLEGDSCSFITQLVNHFWKLHASKPKNAFLAPACLPGLTHIEATVNALVDIIHGYCTCELDCINTASRIYMQMLLCPDPAVSFSCKQALIRVLRPRNKRRHVTLPSSPRSNTPMGDKDDDDDDDADEKMQSSGIPNGGHIRQESQEQSEVDHGDFEMVSESMVLETAENVNNGNPSPLEALLAGAEGFPPMLDIPPDADDETMVELAIALSLQQDQQGSSSSALGLQSLGLSGQAPSSSSLDAGTLSDTTASAPASDDEGSTAATDGSTLRTSPADHGGSVGSESGGSAVDSVAGEHSVSGRSSAYGDATAEGHPAGPGSVSSSTGAISTTTGHQEGDGSEGEGEGDGEADVHASNRLHMVRLMLLERLLQTLPQLRSVGGVRAIPYMQVILMLTTDLDGEDEKDKGALDNLLSQLIAELGMDKKDVSRKSERSALNEVHLVLMRLLSVFMSRTKSGSKASVCESSSLISSATAAALLSSGAVDYCLHVLKSLLEHWKSQQSDEEPVATSQLLKPHTTSSPPDMSPFFLRQYVKGHAADVFEAYTQLLTEMVLRLPYQIKKIADTNSRIPPPVFDHSWFYFLSEYLMIQQTPFVRRQVRKLLLFICGSKEKYRQLRDLHTLDSHVRGIKKLLEEQGIFLRASVVTASSGSALQYDTLISLMEHLKACAEIAAQRTVNWQRFCIKDDSVLYFLLQVSFLVDEGVSPVLLQLLSCALCGSKVLAALAASAGSSSTSSSSAPAAASSGQATAQPKSSTKKSKKEEKEKEKEGESSGSQEDQLCTALVNQLNKFADKETLVQFLRCFLLESNSSSVRWQAHCLTLHIYRNSSKSQQELLLDLMWSIWPELAAYGRKAAQFVDLLGYFSLKTPQTEKKLKEYSQKAVEILRTQNHILTNHPNSNIYNALSGLVEFDGCYLESGPCLVCNNPEVPLCYIKLSSIKVDTRYTTTQQVVKLIGSHTISKVTVKIGDLKRTKMVRTINLYYNNRTVQAIVELKNKPARWHKAKKVQLTPGQTEVKIDLPLPIVASNLMIEFADFYENYQASTETLQCPRCSASVPANPGVCGNCGENVYQCHKCRSINYDEKDPFLCNACGFCKYARFDFMLYAKPCCAVDPIENEEDRKKAVSNINTLLDKADRVYHQLMGHRPQLENLLCKVNEAAPEKPQDDSGTSGGISSTSASVNRYILQLAQEYCGDCKSSFDELSKIIQKVFASRKELLEYDLQQREAATKSSRTSVQPTFTASQYRALSVLGCGHTSSTKCYGCASAVTEHCITLLRALATNPALRHILVSQGLIRELFDYNLRRGSAAMREEVRQLMCLLTRDNPEATQQMNDLIIGKVSTALKGHWANPDLASSLQYEMLLLTDSISKEDSCWELRLRCALSLFLMAVNIKTPVVVENITLMCLRILQKLIKPPAPTSKKNKDVPVEALTTVRPYCNEIHAQAQLWLKRDPKASYDAWKKCLPIRGVDGNGKSPSKAELRHLYLTEKYVWRWKQFLSRRGKRTPPLDLQLGHNNWLRQVLFTPATQAARQAACTIVEALATIPSRKQQVLDLLTSYLDELSVAGECAAEYLALYQKLITSAHWKVYLAARGVLPYVGNLITKEIARLLALEEATLSTDLQQGYALKSLTGLLSSFVEVESIKRHFKSRLVGTVLNGYLCLRKLVVQRTKLIDETQDMLLEMLEDMTTGTESETKAFMAVCIETAKRYNLDDSRTPVFIFERLCSIIYPEENEVTEFFVTLEKDPQQEDFLQGRMPGNPYSSNEPGIGPLMRDIKNKICQDCDLVALLEDDSGMELLVNNKIISLDLPVAEVYKKVWCTTNEGEPMRIVYRMRGLLGDATEEFIESLDSTTDEEEDEEEVYKMAGVMAQCGGLECMLNRLAGIKDFKQGRHLLTVLLKLFSYCVKVKVNRQQLVKLEMNTLNVMLGTLNLALVAEQESKDSGGAAVAEQVLSIMEIILDESNAEPLSEDKGNLLLTGDKDQLVMLLDQINSTFVRSNPSVLQGLLRIIPYLSFGEVEKMQILVERFKPYCSFDKYDEDHSGDDKVFLDCFCKIAAGIKNNSNGHQLKDLILQKGITQSALDYMKKHIPSAKNLDADIWKKFLSRPALPFILRLLRGLAIQHPATQVLIGTDSITNLHKLEQVSSDEGIGTLAENLLEALREHPDVNKKIDAARRETRAEKKRMAMAMRQKALGTLGMTTNEKGQVVTKTALLKQMEELIEEPGLTCCICREGYKFQPTKVLGIYTFTKRVALEEMESKPRKQQGYSTVSHFNIVHYDCHLAAVRLARGREEWESAALQNANTKCNGLLPVWGPHVPESAFATCLARHNTYLQECTGQREPTYQLNIHDIKLLFLRFAMEQSFSADTGGGGRESNIHLIPYIVHTVLYVLNTTRATSREEKNLQGFLEQPKEKWVESAFEVDGPHYFTVLALHVLPPEKWRAVRVEILRRLLVTSQARAVSPGGATRLTDKALKDYSAYRSSLLFWALVDLIYNMFKKVPTSNTEGGWSCSLAEYIRHNDMPIHEAADKALKAFQEEFMPAETFSEFLDAAGLLSEVTDAESFLKDLLNSVP", "length": 4985, "header": "tr|A0AAA9TWT8-1|A0AAA9TWT8_BOVIN Computationally mapped isoform of Ubiquitin protein ligase E3 component n-recognin 4 OS=Bos taurus OX=9913 GN=UBR4 PE=3 SV=1 CANONICAL=A0AAA9TU63-1" }, "locus": { "chromosome": "2", "start_pos": 133588979, "end_pos": 133452278, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000120523.1", "url": "https://www.ensembl.org/id/ENSBTAT00000120523.1" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000101051.1", "url": "https://www.ensembl.org/id/ENSBTAP00000101051.1" } ] } }, { "isoform_ac": "E1BHT5-1", "url": "https://www.uniprot.org/uniprotkb/E1BHT5/entry", "sequence": { "sequence": "MATSGGEEAAAVAPAVGAPAPAGDTTPGWEVAVRPLLSASYSAFEMKELPQLVASVIESESEILQHEKQYEPFYSSFVALSTHYITTVCSLIPRNQLQSVAAACKVLIEFSLLRLENPDEACAVSQKHLILLIKGLCTGCSRLDRTEIITFTAMMKSAKLPQTVKTLSDVEDQKELASPVSPELKQKEVQMNFLNQLTSVFNPRTVASSPVGPQTQAEGESEEQSSTDQASAIKTKNVFIAQNVASLQELGGSEKLLRVCLNLPYFLRYINRFQDAVLANSFFIMPATVADATAVRNGFHSLVIDVTMALDTLSLPVLEPLNPSRLQDVTVLSLSCLYAGVSVATCTAILHVGGAQQARTGCTSSKEEDHEGDAATIVQKCLEIYDMIGQAISSSRRAGGEHYQNFQLLGAWCLLNSLFLILNLSPTALADKGKEKDPLAALRVRDILSRTKEGVGSPKLGPGKGHQGFGVLSVILANHAVKLLTSLFQDLQVEALHKGWEADGPPAVLSIMAQSTSIQRIQRLIDSVPLTNLLLTLLSTSYRKACVLQRQRKGSMSSDASASTDSNTYYEDDFSSTEEDSSQDEDSEPILGQWFEETISPSKEKVAPPPPPPSPPLESSPRVKSPSKQAPGEKGNILASRKDPELFLGLASNILNFITSSMLNSRSNFIRNYLSVSLSEHHMATLASIIKEVDKDGLKGASDEEFAAALYHFNHSLVTSDLQPPNLQNTLLQQLGVAPFSEGPWPLYIHPQSLSVLSRLLLIWQHKASAQGDPDVPECLKVWDRFLSTMKQNALQGVVPAETEDLNVEHLQLLLLIFHNFSEKGRRDILTLFVQITQELSASMDAQMRSVPLILARLLLIFDYLLHQYSKAPMYLFEQVQHNLLSPPFGWASGSQDSSSRRTTTPLYHGFKEVEENWSKHFSSDAVPQPRFYCVLSPEASEDDLNRLDSVACDVLFSKLVKYDELYTALTSLLAAGSQLDTVRRKENKNVTALEACALQYYFLILWRILGILPPSKTYMNQLAMNSPEMSECDILHTLRWSSRLRISSYVNWIKDHLIKQGMKAEHAGSLLELASSKCSSVKYDVDIVEEYFARQISSFCSIDCTTILQLHEIPSLQSIYTLDAAVSKVQVSLDEHFSKVAAETDPQKSSEVTKNLLPATLQLIDTYASFTRAYLLQNFNEEGSTEKPSQEKLHGFAAVLAIGSSRCKANTLGPTLVQNLPSSVQTVCESWNNISTNEFPNIGSWRNAFANDTVPSESYISAVQAAHLGTLCGQSLPLAASLKHTLLSLVRLTGDLIVWSDEMNPPQVIRTLLPLLLESSTESVAEISSNSLERVLGPAESDEFLARVYEKLITGCYNILANHADPNSGLDESILEECLQYLEKQLESSQARKAMEDFFSDSGELVQIMMATANENLSAKFCNRVLKFFTKLFQLTEKSPNPSLLHLCGSLAQLACVEPARLQAWLTRMTASPPKDSDQLDVIQENRQLLQLLTTYIVRENSQVGEGVCAVLLGTLIPMATEMLANGDGTGFPELMVVMATLAGAGQGAGHLQLHNAAVDWLSRCKKYLSQKNVVEKLNANVMHGKHVMVLECTCHIMSYLADVTNALSQSNGQGPSHLSVDGEERAIEVDSDWVEELAVEEEDSQAEDSDEDSLCNKLCTFTITQKEFMNQHWYHCHTCKMVDGVGVCTVCAKVCHKDHEISYAKYGSFFCDCGAKEDGSCLALVKRTPSSGMSSTMKESAFQTEPRVSESLVRHTSTSPADKAKVTISDGKVADEEKPKKSSLCRTVEGCREELQNQANFSFAPLVLDMLSFLMDAIQTNFQQASAVGSSSRAQQALRELHTVDKAVEMTDQLMVPTLGSQEGAFENVRMNYSGDQGQTIRQLISAHVLRRVAMCVLSSPHGRRQHLAVSHEKGKITVLQLSALLKQADSSKRKLTLTRLASAPVPFTVLSLTGNPCKEDYLAVCGLKDCHVLTFSSSGSVSDHLVLHPQLATGNFIIKAVWLPGSQTELAIVTADFVKVYDLSVDALSPAFYFLLPSSKIRDVTFLFNEEGKNIIVIMSSAGYIYTQLMEEASSAQQGPFYVTNVLEVNHEDLKDSNSQVAGGGVSVYYSHVLQMLFFSYCQGRSFAATVSRTTLEVLQLFSINIKSPNGGSKAPPALCQWSEVMNHPGLVCCVQQTTGVPLVVMVKPDTFLIQEIKTLPAKAKIQDMVAIRHTACNEQQRTTMILLCEDGSLRIYMANVENTSYWLQPSLQPSSVISIMKPVRKRKTATITARTSSQVAFPIDFFEHNQQLSDVEFGGNDLLQVYNAQQIKHRLNSTGMYVANTKPGGFTIEISNNNSTMVMTGMRIQIGTQAIERAPSYIEIFGRTMQLNLSRSRWFDFPFTREEALQADKKLNLFIGASVDPAGVTMIDAVKIYGKTKEQFGWPDEPPEEFPAASVSNICPSNLTQSNGTGDSDSAAPAVTGGTVLERLVVSSLEALESCFAVGPIIEKERNKNAAQELATLLLSLPAPASVQQQSKSLLASLHTSRSAYHSHKDQALLSKAVQCLNTSSKEGKDLDPEVFQRLVVTARSIAVTRPNNLVHFTESRLPQTETDCFFPRCACWNLGIVGILIGAPLETPSPEGADEGREPQKQLEGDSCSFITQLVNHFWKLHASKPKNAFLAPACLPGLTHIEATVNALVDIIHGYCTCELDCINTASRIYMQMLLCPDPAVSFSCKQALIRVLRPRNKRRHVTLPSSPRSNTPMGDKDDDDDDDADEKMQSSGIPNGGHIRQESQEQSEVDHGDFEMVSESMVLETAENVNNGNPSPLEALLAGAEGFPPMLDIPPDADDETMVELAIALSLQQDQQGSSSSALGLQSLGLSGQAPSSSSLDAGTLSDTTASAPASDDEGSTAATDGSTLRTSPADHGGSVGSESGGSAVDSVAGEHSVSGRSSAYGDATAEGHPAGPGSVSSSTGAISTTTGHQEGDGSEGEGEGDGEADVHASNRLHMVRLMLLERLLQTLPQLRSVGGVRAIPYMQVILMLTTDLDGEDEKDKGALDNLLSQLIAELGMDKKDVSRKSERSALNEVHLVLMRLLSVFMSRTKSGSKASVCESSSLISSATAAALLSSGAVDYCLHVLKSLLEHWKSQQSDEEPVATSQLLKPHTTSSPPDMSPFFLRQYVKGHAADVFEAYTQLLTEMVLRLPYQIKKIADTNSRIPPPVFDHSWFYFLSEYLMIQQTPFVRRQVRKLLLFICGSKEKYRQLRDLHTLDSHVRGIKKLLEEQGIFLRASVVTASSGSALQYDTLISLMEHLKACAEIAAQRTVNWQRFCIKDDSVLYFLLQVSFLVDEGVSPVLLQLLSCALCGSKVLAALAASAGSSSTSSSSAPAAASSGQATAQPKSSTKKSKKEEKEKEKEGESSGSQEDQLCTALVNQLNKFADKETLVQFLRCFLLESNSSSVRWQAHCLTLHIYRNSSKSQQELLLDLMWSIWPELAAYGRKAAQFVDLLGYFSLKTPQTEKKLKEYSQKAVEILRTQNHILTNHPNSNIYNALSGLVEFDGCYLESGPCLVCNNPEVPLCYIKLSSIKVDTRYTTTQQVVKLIGSHTISKVTVKIGDLKRTKMVRTINLYYNNRTVQAIVELKNKPARWHKAKKVQLTPGQTEVKIDLPLPIVASNLMIEFADFYENYQASTETLQCPRCSASVPANPGVCGNCGENVYQCHKCRSINYDEKDPFLCNACGFCKYARFDFMLYAKPCCAVDPIENEEDRKKAVSNINTLLDKADRVYHQLMGHRPQLENLLCKVNEAAPEKPQDDSGTSGGISSTSASVNRYILQLAQEYCGDCKSSFDELSKIIQKVFASRKELLEYDLQQREAATKSSRTSVQPTFTASQYRALSVLGCGHTSSTKCYGCASAVTEHCITLLRALATNPALRHILVSQGLIRELFDYNLRRGSAAMREEVRQLMCLLTRDNPEATQQMNDLIIGKVSTALKGHWANPDLASSLQYEMLLLTDSISKEDSCWELRLRCALSLFLMAVNIKTPVVVENITLMCLRILQKLIKPPAPTSKKNKDVPVEALTTVRPYCNEIHAQAQLWLKRDPKASYDAWKKCLPIRGVDGNGKSPSKAELRHLYLTEKYVWRWKQFLSRRGKRTPPLDLQLGHNNWLRQVLFTPATQAARQAACTIVEALATIPSRKQQVLDLLTSYLDELSVAGECAAEYLALYQKLITSAHWKVYLAARGVLPYVGNLITKEIARLLALEEATLSTDLQQGYALKSLTGLLSSFVEVESIKRHFKSRLVGTVLNGYLCLRKLVVQRTKLIDETQDMLLEMLEDMTTGTESETKAFMAVCIETAKRYNLDDSRTPVFIFERLCSIIYPEENEVTEFFVTLEKDPQQEDFLQGRMPGNPYSSNEPGIGPLMRDIKNKICQDCDLVALLEDDSGMELLVNNKIISLDLPVAEVYKKVWCTTNEGEPMRIVYRMRGLLGDATEEFIESLDSTTDEEEDEEEVYKMAGVMAQCGGLECMLNRLAGIKDFKQGRHLLTVLLKLFSYCVKVKVNRQQLVKLEMNTLNVMLGTLNLALVAEQESKDSGGAAVAEQVLSIMEIILDESNAEPLSEDKGNLLLTGDKDQLVMLLDQINSTFVRSNPSVLQGLLRIIPYLSFGEVEKMQILVERFKPYCSFDKYDEDHSGDDKVFLDCFCKIAAGIKNNSNGHQLKDLILQKGITQSALDYMKKHIPSAKNLDADIWKKFLSRPALPFILRLLRGLAIQHPATQVLIGTDSITNLHKLEQVSSDEGIGTLAENLLEALREHPDVNKKIDAARRETRAEKKRMAMAMRQKALGTLGMTTNEKGQVVTKTALLKQMEELIEEPGLTCCICREGYKFQPTKVLGIYTFTKRVALEEMESKPRKQQGYSTVSHFNIVHYDCHLAAVRLARGREEWESAALQNANTKCNGLLPVWGPHVPESAFATCLARHNTYLQECTGQREPTYQLNIHDIKLLFLRFAMEQSFSADTGGGGRESNIHLIPYIVHTVLYVLNTTRATSREEKNLQGFLEQPKEKWVESAFEVDGPHYFTVLALHVLPPEKWRAVRVEILRRLLVTSQARAVSPGGATRLTDKALKDYSAYRSSLLFWALVDLIYNMFKKVPTSNTEGGWSCSLAEYIRHNDMPIHEAADKALKAFQEEFMPAETFSEFLDAAGLLSEVTDAESFLKDLLNSVP", "length": 5209, "header": "tr|E1BHT5-1|E1BHT5_BOVIN Computationally mapped isoform of Ubiquitin protein ligase E3 component n-recognin 4 OS=Bos taurus OX=9913 GN=UBR4 PE=3 SV=3 CANONICAL=A0AAA9TU63-1" }, "locus": { "chromosome": "2", "start_pos": 133588979, "end_pos": 133452143, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000020277.7", "url": "https://www.ensembl.org/id/ENSBTAT00000020277.7" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000020277.7", "url": "https://www.ensembl.org/id/ENSBTAP00000020277.7" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [ { "id": "R-BTA-6798695", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-BTA-6798695", "resource": "Reactome", "description": "Neutrophil degranulation" }, { "id": "R-BTA-983168", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-BTA-983168", "resource": "Reactome", "description": "Antigen processing: Ubiquitination & Proteasome degradation" } ], "orthologs": [], "go_annotation": { "categories": [ { "name": "Molecular Function", "total": 4, "go_terms": [ { "name": "calmodulin binding", "id": "GO:0005516", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005516", "evidence": [ { "database": "UniProtKB", "id": "A0AAA9TU63", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TU63" } ], "pmid": "" }, { "name": "zinc ion binding", "id": "GO:0008270", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008270", "evidence": [ { "database": "UniProtKB", "id": "A0AAA9TU63", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TU63" } ], "pmid": "" }, { "name": "ubiquitin protein ligase activity", "id": "GO:0061630", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0061630", "evidence": [ { "database": "UniProtKB", "id": "A0AAA9TU63", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TU63" } ], "pmid": "" }, { "name": "ubiquitin-like ligase-substrate adaptor activity", "id": "GO:1990756", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:1990756", "evidence": [ { "database": "UniProtKB", "id": "A0AAA9TU63", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TU63" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 4, "go_terms": [ { "name": "nucleoplasm", "id": "GO:0005654", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005654", "evidence": [ { "database": "UniProtKB", "id": "A0AAA9TU63", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TU63" } ], "pmid": "" }, { "name": "endosome", "id": "GO:0005768", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005768", "evidence": [ { "database": "UniProtKB", "id": "A0AAA9TU63", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TU63" } ], "pmid": "" }, { "name": "cytosol", "id": "GO:0005829", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005829", "evidence": [ { "database": "UniProtKB", "id": "A0AAA9TU63", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TU63" } ], "pmid": "" }, { "name": "cytoplasm", "id": "GO:0005737", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005737", "evidence": [ { "database": "UniProtKB", "id": "A0AAA9TU63", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TU63" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 13, "go_terms": [ { "name": "response to oxidative stress", "id": "GO:0006979", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006979", "evidence": [ { "database": "UniProtKB", "id": "A0AAA9TU63", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TU63" } ], "pmid": "" }, { "name": "negative regulation of fatty acid biosynthetic process", "id": "GO:0045717", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0045717", "evidence": [ { "database": "UniProtKB", "id": "A0AAA9TU63", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TU63" } ], "pmid": "" }, { "name": "endosome organization", "id": "GO:0007032", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007032", "evidence": [ { "database": "UniProtKB", "id": "A0AAA9TU63", "url": 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CANONICAL=A0AAA9TS74-1" }, "locus": { "chromosome": "17", "start_pos": 71812039, "end_pos": 71801715, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000133665.1", "url": "https://www.ensembl.org/id/ENSBTAT00000133665.1" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000101229.1", "url": "https://www.ensembl.org/id/ENSBTAP00000101229.1" } ] } }, { "isoform_ac": "E1BJ06-1", "url": "https://www.uniprot.org/uniprotkb/E1BJ06/entry", "sequence": { "sequence": "MRSSLTPLGPSVSRDRVISSFPKWYTPAACLQLREHFHGQVSTACQRGNTGTVGFCKNVFDHDYKATIGVDFEIERFEVAGTPFSLQIWDTAGQEKFKCIASAYYRGAQVIITAFDLTDVQTLEHSRQWLEDALRENEPGACFVFLVGTKKDLLSGAACEQAEAEAVRLANEMRAEYWSVSAKTGENVKAFFSRVAALAFERSVLQDLERRSNSPLQVGGGDVIRMEGRRPETPDSRRPSGPSCC", "length": 245, "header": "tr|E1BJ06-1|A0AAA9TS74_BOVIN Computationally mapped isoform of Ras-related protein Rab-36 OS=Bos taurus OX=9913 GN=RAB36 PE=3 SV=4 CANONICAL=A0AAA9TS74-1" }, "locus": { "chromosome": "17", "start_pos": 71812039, "end_pos": 71801715, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000017437.7", "url": "https://www.ensembl.org/id/ENSBTAT00000017437.7" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000017437.7", "url": "https://www.ensembl.org/id/ENSBTAP00000017437.7" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [ "enzyme" ], "publication": [], "pathway": [ { "id": "bta:518312", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?bta:518312", "resource": "KEGG Pathway" }, { "id": "R-BTA-6811438", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-BTA-6811438", "resource": "Reactome", "description": "Intra-Golgi traffic" }, { "id": "R-BTA-8873719", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-BTA-8873719", "resource": "Reactome", "description": "RAB geranylgeranylation" } ], "orthologs": [], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 1, "go_terms": [ { "name": "Golgi membrane", "id": "GO:0000139", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000139", "evidence": [ { "database": "UniProtKB", "id": "A0AAA9TS74", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TS74" } ], "pmid": "" } ] }, { "name": "Molecular Function", "total": 4, "go_terms": [ { "name": "GTP binding", "id": "GO:0005525", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005525", "evidence": [ { "database": "UniProtKB", "id": "A0AAA9TS74", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TS74" } ], "pmid": "" }, { "name": "metal ion binding", "id": "GO:0046872", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0046872", "evidence": [ { "database": "UniProtKB", "id": "A0AAA9TS74", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TS74" } ], "pmid": "" }, { "name": "G protein activity", "id": "GO:0003925", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003925", "evidence": [ { "database": "UniProtKB", "id": "A0AAA9TS74", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TS74" } ], "pmid": "" }, { "name": "GTPase activity", "id": "GO:0003924", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003924", "evidence": [ { "database": "UniProtKB", "id": "A0AAA9TS74", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TS74" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 2, "go_terms": [ { "name": "protein transport", "id": "GO:0015031", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0015031", "evidence": [ { "database": "UniProtKB", "id": "A0AAA9TS74", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TS74" } ], "pmid": "" }, { "name": "vesicle-mediated transport", "id": "GO:0016192", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016192", "evidence": [ { "database": "UniProtKB", "id": "A0AAA9TS74", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TS74" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [], "ptm_annotation": [], "interactions": [], "reactions": [ { "id": "19669", "name": "", "equation": "GTP + H2O = GDP + phosphate + H(+)", "summary": "", "cellular_location": "", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [ "Q08E00-1", "Q5E9J3-1", "A6QP66-1", "Q2KHU8-1", "Q2KIA5-1", "F1MM29-1", "P08239-1", "P04896-1", "P63097-1", "Q7YS69-1", "Q0VCJ7-1", "A0AAA9SVR8-1", "P81948-1", "Q2KJ93-1", "A0AAA9TES1-1", "P61223-1", "Q2HJB8-1", "Q0IIG7-1", "Q3ZCJ7-1", "Q27957-1", "Q2HJ86-1", "A0A3Q1LMP2-1", "F1MB25-1", "Q58DS9-1", "A0AAA9S306-1", "A0A3Q1NEF8-1", "A4FV54-1", "A6H7I5-1", "F2Z4D5-1", "G3N1U2-1", "O18956-1", "P62998-1", "Q32KN8-1", "Q3MHP2-1", "Q3T054-1", "Q3T0F5-1", "Q3T0T7-1", "Q56JV3-1", "F1MNI4-1", "Q8HZJ5-1", "P61585-1", "P62833-1", "P68103-1", "Q08DI5-1", "Q2HJH2-1", "Q2T9U1-1", "Q2TBH7-1", "Q3MHP5-1", "Q3SX43-1", "Q3SYU2-1", "P81947-1", "P84080-1", "Q08DF4-1", "Q2KI07-1", "Q2TA29-1", "Q3T0D7-1", "A6QLJ3-1", "A6QNM2-1", "A6QR46-1", "Q1LZ78-1", "Q2KHZ2-1", "G3MYK6-1", "Q58D56-1", "Q32KW9-1", "P11023-1", "Q58DW6-1", "Q9TU25-1", "P10948-1", "Q2HJI8-1", "P10949-1", "Q0IIG8-1", "Q29RR0-1", "Q32PH8-1", "Q58DS5-1", "Q1RMR4-1", "Q3ZC27-1", "P49410-1", "A0A140T898-1", "E1BPU0-1", "A0AAA9S5W8-1", "A0AAA9SLN0-1", "A0AAF6Z672-1", "Q17R06-1", "Q58D72-1", "P82922-1", "Q2HJF8-1", "Q17QU4-1", "Q2YDM7-1", "A0AAA9T9T1-1", "A0A3Q1MDX0-1", "F1N2J9-1", "Q17QB7-1", "Q3SWY9-1", "Q5E9M9-1", "A0A3S5ZPA2-1", "A0AAA9SV95-1", "A0AAA9TWE6-1", "F1N6Y7-1", "F1N7V2-1", "A0AAA9SGM6-1", "A0AAA9TNQ2-1", "A0AAA9TS74-1", "F6Q1G9-1", "A0AAF6YXF5-1", "A5D7J5-1", "P04695-1", "Q3ZBW5-1", "A4FUD1-1", "A0A3Q1M0B9-1", "A6H7F2-1", "F1MHP4-1", "A0A3Q1MGR4-1", "A0A3Q1NCE9-1", "Q0P5E2-1", "Q32LJ6-1", "Q58DC5-1", "Q08DA0-1", "A0ABI0NND0-1", "E1BJA0-1", "A0A3Q1N147-1", "A0AAF6YME1-1", "F1MX39-1", "Q1RMJ6-1", "Q2HJ68-1", "Q2HJG3-1", "Q17QI8-1", "Q3SZA1-1", "A0ABI0NZ89-1", "A0ABI0P4Y3-1" ], "evidence": [ { "id": "19669", "database": "Rhea", "url": "https://www.rhea-db.org/rhea/19669" } ] }, { "id": "R-BTA-8849748", "name": "The COG complex binds RABs at the Golgi membrane", "equation": "", "summary": "This event has been computationally inferred from an event that has been demonstrated in another species.

The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.

More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "cellular_location": "Golgi membrane", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [ "A0AAA9TS74-1", "Q17QB7-1" ], "evidence": [ { "id": "R-BTA-8849748", "database": "Reactome", "url": "https://www.reactome.org/PathwayBrowser/#R-BTA-8849748" } ] }, { "id": "R-BTA-8870466", "name": "RGGT:CHM binds RABs", "equation": "", "summary": "This event has been computationally inferred from an event that has been demonstrated in another species.

The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.

More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "cellular_location": "cytosol", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [ "Q0IIG7-1", "Q8HZJ5-1", "A0A140T898-1", "F1MNI4-1", "Q3MHP2-1", "A0A3S5ZPA2-1", "A6QR46-1", "Q3ZC27-1", "A0AAA9TS74-1", "A0AAA9SV95-1", "A0A3Q1MGR4-1", "P10948-1", "Q2TBH7-1", "F1N2J9-1", "P10949-1", "P11023-1", "Q17R06-1", "A0A3Q1MWA3-1", "F1N7V2-1", "A4FV54-1", "F2Z4D5-1", "Q58DW6-1", "Q17QB7-1", "Q17QU4-1", "Q1RMR4-1", "Q5E9B3-1", "Q5EA80-1", "E1BJA0-1" ], "evidence": [ { "id": "R-BTA-8870466", "database": "Reactome", "url": "https://www.reactome.org/PathwayBrowser/#R-BTA-8870466" } ] }, { "id": "R-BTA-8870469", "name": "RGGT geranylgeranylates RAB proteins", "equation": "", "summary": "This event has been computationally inferred from an event that has been demonstrated in another species.

The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.

More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "cellular_location": "cytosol", "input_participant_list": [ "R-ALL-1131164" ], "output_participant_list": [], "enzyme_list": [ "Q0IIG7-1", "Q8HZJ5-1", "A0A140T898-1", "F1MNI4-1", "Q3MHP2-1", "A0A3S5ZPA2-1", "A6QR46-1", "Q3ZC27-1", "A0AAA9TS74-1", "A0AAA9SV95-1", "A0A3Q1MGR4-1", "P10948-1", "Q2TBH7-1", "F1N2J9-1", "P10949-1", "P11023-1", "Q17R06-1", "A0A3Q1MWA3-1", "F1N7V2-1", "A4FV54-1", "F2Z4D5-1", "Q58DW6-1", "Q17QB7-1", "Q17QU4-1", "Q1RMR4-1", "Q5E9B3-1", "Q5EA80-1", "E1BJA0-1" ], "evidence": [ { "id": "R-BTA-8870469", "database": "Reactome", "url": "https://www.reactome.org/PathwayBrowser/#R-BTA-8870469" } ] } ], "reaction_participants": [ { "participant_id": "R-ALL-1131164", "participant_name": "geranylgeranyl diphosphate [cytosol]", "crossref": [ { "id": "48861", "database": "ChEBI", "url": "" }, { "id": "C00353", "database": "COMPOUND", "url": "" }, { "id": "3052", "database": "Guide to Pharmacology - Ligands", "url": "" }, { "id": "ZINC000012495043", "database": "ZINC", "url": "" }, { "id": "HMDB0004486", "database": "HMDB Metabolite", "url": "" } ] } ], "reaction_enzymes": [ { "uniprot_ac": "A0A140T898", "gene_name": "RAB13", "activity": [ { "ec_number": "3.6.5.2", "activity": "GTP + H2O = GDP + phosphate + H(+).", "evidence": [ { "id": "A0A140T898", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A140T898" } ] }, { "ec_number": "3.6.5.2", "activity": "", "evidence": [ { "id": "A0A140T898", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A140T898" } ] } ] }, { "uniprot_ac": "A0A3Q1LMP2", "gene_name": "KRAS", "activity": [ { "ec_number": "3.6.5.2", "activity": "GTP + H2O = GDP + phosphate + H(+).", "evidence": [ { "id": "A0A3Q1LMP2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1LMP2" } ] }, { "ec_number": "3.6.5.2", "activity": "", "evidence": [ { "id": "A0A3Q1LMP2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1LMP2" } ] } ] }, { "uniprot_ac": "A0A3Q1M0B9", "gene_name": "RASEF", "activity": [ { "ec_number": "3.6.5.2", "activity": "GTP + H2O = GDP + phosphate + H(+).", "evidence": [ { "id": "A0A3Q1M0B9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1M0B9" } ] }, { "ec_number": "3.6.5.2", "activity": "", "evidence": [ { "id": "A0A3Q1M0B9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1M0B9" } ] } ] }, { "uniprot_ac": "A0A3Q1MDX0", "gene_name": "DNM3", "activity": [ { "ec_number": "3.6.5.5", "activity": "GTP + H2O = GDP + phosphate + H(+).", "evidence": [ { "id": "A0A3Q1MDX0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1MDX0" } ] }, { "ec_number": "3.6.5.5", "activity": "", "evidence": [ { "id": "A0A3Q1MDX0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1MDX0" } ] } ] }, { "uniprot_ac": "A0A3Q1MGR4", "gene_name": "RAB37", "activity": [ { "ec_number": "3.6.5.2", "activity": "GTP + H2O = GDP + phosphate + H(+).", "evidence": [ { "id": "A0A3Q1MGR4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1MGR4" } ] }, { "ec_number": "3.6.5.2", "activity": "", "evidence": [ { "id": "A0A3Q1MGR4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1MGR4" } ] } ] }, { "uniprot_ac": "A0A3Q1MWA3", "gene_name": "RAB1B", "activity": [ { "ec_number": "3.6.5.2", "activity": "GTP + H2O = GDP + phosphate + H(+).", "evidence": [ { "id": "A0A3Q1MWA3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1MWA3" } ] }, { "ec_number": "3.6.5.2", "activity": "", "evidence": [ { "id": "A0A3Q1MWA3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1MWA3" } ] } ] }, { "uniprot_ac": "A0A3Q1N147", "gene_name": "RAB1A", "activity": [ { "ec_number": "3.6.5.2", "activity": "GTP + H2O = GDP + phosphate + H(+).", "evidence": [ { "id": "A0A3Q1N147", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1N147" } ] }, { "ec_number": "3.6.5.2", "activity": "", "evidence": [ { "id": "A0A3Q1N147", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1N147" } ] } ] }, { "uniprot_ac": "A0A3Q1NCE9", "gene_name": "", "activity": [ { "ec_number": "3.6.5.2", "activity": "GTP + H2O = GDP + phosphate + H(+).", "evidence": [ { "id": "A0A3Q1NCE9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1NCE9" } ] }, { "ec_number": "3.6.5.2", "activity": "", "evidence": [ { "id": "A0A3Q1NCE9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1NCE9" } ] } ] }, { "uniprot_ac": "A0A3Q1NEF8", "gene_name": "RAC1", "activity": [ { "ec_number": "3.6.5.2", "activity": "GTP + H2O = GDP + phosphate + H(+).", "evidence": [ { "id": "A0A3Q1NEF8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1NEF8" } ] }, { "ec_number": "3.6.5.2", "activity": "", "evidence": [ { "id": "A0A3Q1NEF8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1NEF8" } ] } ] }, { "uniprot_ac": "A0A3S5ZPA2", "gene_name": "RAB40B", "activity": [ { "ec_number": "3.6.5.2", "activity": "GTP + H2O = GDP + phosphate + H(+).", "evidence": [ { "id": "A0A3S5ZPA2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3S5ZPA2" } ] }, { "ec_number": "3.6.5.2", "activity": "", "evidence": [ { "id": "A0A3S5ZPA2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3S5ZPA2" } ] } ] }, { "uniprot_ac": "A0AAA9S306", "gene_name": "OPA1", "activity": [ { "ec_number": "3.6.5.5", "activity": "GTP + H2O = GDP + phosphate + H(+).", "evidence": [ { "id": "A0AAA9S306", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9S306" } ] }, { "ec_number": "3.6.5.5", "activity": "", "evidence": [ { "id": "A0AAA9S306", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9S306" } ] } ] }, { "uniprot_ac": "A0AAA9S5W8", "gene_name": "RAB12", "activity": [ { "ec_number": "3.6.5.2", "activity": "GTP + H2O = GDP + phosphate + H(+).", "evidence": [ { "id": "A0AAA9S5W8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9S5W8" } ] }, { "ec_number": "3.6.5.2", "activity": "", "evidence": [ { "id": "A0AAA9S5W8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9S5W8" } ] } ] }, { "uniprot_ac": "A0AAA9SGM6", "gene_name": "", "activity": [ { "ec_number": "3.6.5.2", "activity": "GTP + H2O = GDP + phosphate + H(+).", "evidence": [ { "id": "A0AAA9SGM6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9SGM6" } ] }, { "ec_number": "3.6.5.2", "activity": "", "evidence": [ { "id": "A0AAA9SGM6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9SGM6" } ] } ] }, { "uniprot_ac": "A0AAA9SLN0", "gene_name": "RAB23", "activity": [ { "ec_number": "3.6.5.2", "activity": "GTP + H2O = GDP + phosphate + H(+).", "evidence": [ { "id": "A0AAA9SLN0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9SLN0" } ] }, { "ec_number": "3.6.5.2", "activity": "", "evidence": [ { "id": "A0AAA9SLN0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9SLN0" } ] } ] }, { "uniprot_ac": "A0AAA9SV95", "gene_name": "RAB34", "activity": [ { "ec_number": "3.6.5.2", "activity": "GTP + H2O = GDP + phosphate + H(+).", "evidence": [ { "id": "A0AAA9SV95", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9SV95" } ] }, { "ec_number": "3.6.5.2", "activity": "", "evidence": [ { "id": "A0AAA9SV95", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9SV95" } ] } ] }, { "uniprot_ac": "A0AAA9SVR8", "gene_name": "LOC789148", "activity": [ { "ec_number": "3.6.5.2", "activity": "GTP + H2O = GDP + phosphate + H(+).", "evidence": [ { "id": "A0AAA9SVR8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9SVR8" } ] }, { "ec_number": "3.6.5.2", "activity": "", "evidence": [ { "id": "A0AAA9SVR8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9SVR8" } ] } ] }, { "uniprot_ac": "A0AAA9T9T1", "gene_name": "ERAS", "activity": [ { "ec_number": "3.6.5.2", "activity": "GTP + H2O = GDP + phosphate + H(+).", "evidence": [ { "id": "A0AAA9T9T1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9T9T1" } ] }, { "ec_number": "3.6.5.2", "activity": "", "evidence": [ { "id": "A0AAA9T9T1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9T9T1" } ] } ] }, { "uniprot_ac": "A0AAA9TES1", "gene_name": "RAB5C", "activity": [ { "ec_number": "3.6.5.2", "activity": "GTP + H2O = GDP + phosphate + H(+).", "evidence": [ { "id": "A0AAA9TES1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TES1" } ] }, { "ec_number": "3.6.5.2", "activity": "", "evidence": [ { "id": "A0AAA9TES1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TES1" } ] 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"MAGISASGSRRRSGPPAPSPGPPPNTGHPPSKRARGIPATPDPEDPFGLHGDFTADDLEELDTLASQALSQCPTTAPDVSNVHKVTRLDGMSKYPAGKNRESVPVKDNFELEVLQAQYKELKEKMKAMEEEVLIKNGEIKILRDSLHQTESILEEQRRSHFLLEQEKTQALSEKEKEFSKKLQSLQSELQFKDAEMNELRTKLQSSERANKLAVPTVSHVSPRKSPSVVIKPEACSPQFGKPSFPTKESFSANKSLPQPCQTEPAYKSPMSREVAENKVHSLGGGPIKQEEPQKSLLDSWRSNNQGSILINLLLKQPLIPGSPLGLCHLLSSCPEAPAGTQFQLPGLGSTLTGISSLRTTGPRDGSFPVSALREAQHMALTGLNLVARNEEGSSDRDPAEGGGRAFPLHRLPGAVHLLPLVQFFIGLHCQALQDLAAAKRSGAPADPPTHPSRVSPGVEASPEDSLYNLEGFSVAALSVLQHLVCHSGAVVCLLLSGAGAEPAAGEGDQSQVHGHSHGDATSAPEGLAKDQGQHPLLKMLLHLLASSSAATGHLQASVLSQCLKVLVELAENASFDFLPRFQCVFRVLPQCLRPETPLPSVLLTVELLSLLVDHEKLAPQLCSHSEGCLLLLLYMYITSRPDRAASETQWLQLEQEAVWLLAKLGVQSPSSPVTASSCQCNVEVVRALTVVLHRQWLTVRRARGPPRTEQQRRTVRCLRDTVLLLHGLSQKDKLFTVHCVEVLHQYDQVMPGVSTLIRGLPDVTDCEVAEGARPGRGRDWLVPAGLGGRTEWWGHPQSRRLWAFTTEPSGFWLRGGPGGSLCRGDRHGRARDGLWLRPVSTEPHGGTRATPVLPSSSD", "length": 858, "header": "tr|A0AAA9TS89-1|A0AAA9TS89_BOVIN Isoform 1 of ATR interacting protein OS=Bos taurus OX=9913 GN=ATRIP PE=4 SV=1 CANONICAL=A0AAA9TS89-1" }, "isoforms": [ { "isoform_ac": "A0AAA9TS89-1", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TS89/entry", "sequence": { "sequence": "MAGISASGSRRRSGPPAPSPGPPPNTGHPPSKRARGIPATPDPEDPFGLHGDFTADDLEELDTLASQALSQCPTTAPDVSNVHKVTRLDGMSKYPAGKNRESVPVKDNFELEVLQAQYKELKEKMKAMEEEVLIKNGEIKILRDSLHQTESILEEQRRSHFLLEQEKTQALSEKEKEFSKKLQSLQSELQFKDAEMNELRTKLQSSERANKLAVPTVSHVSPRKSPSVVIKPEACSPQFGKPSFPTKESFSANKSLPQPCQTEPAYKSPMSREVAENKVHSLGGGPIKQEEPQKSLLDSWRSNNQGSILINLLLKQPLIPGSPLGLCHLLSSCPEAPAGTQFQLPGLGSTLTGISSLRTTGPRDGSFPVSALREAQHMALTGLNLVARNEEGSSDRDPAEGGGRAFPLHRLPGAVHLLPLVQFFIGLHCQALQDLAAAKRSGAPADPPTHPSRVSPGVEASPEDSLYNLEGFSVAALSVLQHLVCHSGAVVCLLLSGAGAEPAAGEGDQSQVHGHSHGDATSAPEGLAKDQGQHPLLKMLLHLLASSSAATGHLQASVLSQCLKVLVELAENASFDFLPRFQCVFRVLPQCLRPETPLPSVLLTVELLSLLVDHEKLAPQLCSHSEGCLLLLLYMYITSRPDRAASETQWLQLEQEAVWLLAKLGVQSPSSPVTASSCQCNVEVVRALTVVLHRQWLTVRRARGPPRTEQQRRTVRCLRDTVLLLHGLSQKDKLFTVHCVEVLHQYDQVMPGVSTLIRGLPDVTDCEVAEGARPGRGRDWLVPAGLGGRTEWWGHPQSRRLWAFTTEPSGFWLRGGPGGSLCRGDRHGRARDGLWLRPVSTEPHGGTRATPVLPSSSD", "length": 858, "header": "tr|A0AAA9TS89-1|A0AAA9TS89_BOVIN Isoform 1 of ATR interacting protein OS=Bos taurus OX=9913 GN=ATRIP PE=4 SV=1 CANONICAL=A0AAA9TS89-1" }, "locus": { "chromosome": "22", "start_pos": 51418837, "end_pos": 51401357, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000113715.1", "url": "https://www.ensembl.org/id/ENSBTAT00000113715.1" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000099345.1", "url": "https://www.ensembl.org/id/ENSBTAP00000099345.1" } ] } }, { "isoform_ac": "F6R7Q2-1", "url": "https://www.uniprot.org/uniprotkb/F6R7Q2/entry", "sequence": { "sequence": "MAGISASGSRRRSGPPAPSPGPPPNTGHPPSKRARGIPATPDPEDPFGLHGDFTADDLEELDTLASQALSQCPTTAPDVSNVHKVTRLDGMSKYPAGKNRESVPVKDNFELEVLQAQYKELKEKMKAMEEEVLIKNGEIKILRDSLHQTESILEEQRRSHFLLEQEKTQALSEKEKEFSKKLQSLQSELQFKDAEMNELRTKLQSSERANKLAVPTVSHVSPRKSPSVVIKPEACSPQFGKPSFPTKESFSANKSLPQPCQTEPAYKSPMSREENKVHSLGGGPIKQEEPQKSLLDSWRSNNQGSILINLLLKQPLIPGSPLGLCHLLSSCPEAPAGTQFQLPGLGSTLTGISSLRTTGPRDGSFPVSALREAQHMALTGLNLVARNEEGSSDRDPAEGGGRAFPLHRLPGAVHLLPLVQFFIGLHCQALQDLAAAKRSGAPADPPTHPSRVSPGVEASPEDSLYNLEGFSVAALSVLQHLVCHSGAVVCLLLSGAGAEPAAGEGDQSQVHGHSHGDATSAPEGLAKDQGQHPLLKMLLHLLASSSAATGHLQASVLSQCLKVLVELAENASFDFLPRFQCVFRVLPQCLRPETPLPSVLLTVELLSLLVDHEKLAPQLCSHSEGCLLLLLYMYITSRPDRAASETQWLQLEQEVVRALTVVLHRQWLTVRRARGPPRTEQQRRTVRCLRDTVLLLHGLSQKDKLFTVHCVEVLHQYDQVMPGVSTLIRGLPDVTDCEEAALEDLCAVETDMDEPEMDCG", "length": 760, "header": "tr|F6R7Q2-1|F6R7Q2_BOVIN Computationally mapped isoform of ATR interacting protein OS=Bos taurus OX=9913 GN=ATRIP PE=4 SV=1 CANONICAL=A0AAA9TS89-1" }, "locus": { "chromosome": "22", "start_pos": 51418837, "end_pos": 51401425, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000054868.3", "url": "https://www.ensembl.org/id/ENSBTAT00000054868.3" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000048150.2", "url": "https://www.ensembl.org/id/ENSBTAP00000048150.2" } ] } } ], "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "other", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 40, "start_aa": "Thr", "end_pos": 40, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr40", "evidence": [ { "id": "", "database": "GlyGen", "url": "https://data.glygen.org/" } ], "filter_code": "000000000000000010000.00000000001000.0.01000" } ], "phosphorylation": [], "glycation": [], "keywords": [ "glycoprotein", "glycoprotein_predicted" ], "publication": [], "pathway": [], "orthologs": [], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 1, "go_terms": [ { "name": "nucleoplasm", "id": "GO:0005654", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005654", "evidence": [ { "database": "UniProtKB", "id": "A0AAA9TS89", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TS89" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 1, "go_terms": [ { "name": "DNA damage checkpoint signaling", "id": "GO:0000077", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000077", "evidence": [ { "database": "UniProtKB", "id": "A0AAA9TS89", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TS89" } ], "pmid": "" } ] }, { "name": "Molecular Function", "total": 1, "go_terms": [ { "name": "K63-linked polyubiquitin modification-dependent protein binding", "id": "GO:0070530", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0070530", "evidence": [ { "database": "UniProtKB", "id": "A0AAA9TS89", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TS89" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 253, "end_pos": 255, "annotation": "n_glycosylation_sequon" }, { "start_pos": 572, "end_pos": 574, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A0AAA9TS89", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TS89" }, { "id": "PF28426", "database": "Pfam", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF28426" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "ATR-interacting protein C-terminal", "eco_id": "ECO_0000259", "start_pos": 315, "end_pos": 768, "start_aa": "Lys", "end_aa": "Val", "glycosite_overlap": [] }, { "evidence": [ { "id": "A0AAA9TS89", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TS89" }, { "id": "PF28409", "database": "Pfam", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF28409" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "ATR-interacting protein N-terminal", "eco_id": "ECO_0000259", "start_pos": 111, "end_pos": 186, "start_aa": "Leu", "end_aa": "Gln", "glycosite_overlap": [] } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [ 40 ], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 253, "end_pos": 255 }, { "start_pos": 572, "end_pos": 574 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 1 }, { "field": "total_sites", "count": 1 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 1 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "exact_sites", "count": 1 }, { "field": "exact_o_linked_sites", "count": 1 }, { "field": "fuzzy_sites", "count": 0 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_pos", "start_aa", "end_pos", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 1 }, { "field": "total_sites", "count": 1 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 1 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "exact_sites", "count": 1 }, { "field": "exact_o_linked_sites", "count": 1 }, { "field": "fuzzy_sites", "count": 0 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_pos", "start_aa", "end_pos", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ], "tool_support": { "graph_view": "yes" } }, { "uniprot_canonical_ac": "A0AAA9TSG6-1", "uniprot_ac": "A0AAA9TSG6", "uniprot_id": "A0AAA9TSG6_BOVIN", "mass": { "chemical_mass": 137703.0, "monoisotopic_mass": 137703.0 }, "refseq": { "ac": "XP_010813165", "name": "rho GTPase-activating protein 33 isoform X3", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_010813165" }, "gene_names": [ { "name": "ARHGAP33", "type": "recommended", "evidence": [ { "id": "A0AAA9TSG6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TSG6" } ] }, { "name": "ARHGAP33", "type": "synonym", "evidence": [ { "id": "XP_010813165", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_010813165" } ] } ], "protein_names": [ { "name": "Rho GTPase-activating protein 33", "type": "recommended", "evidence": [ { "id": "A0AAA9TSG6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TSG6/entry#names_and_taxonomy" } ] }, { "name": "Rho-type GTPase-activating protein 33", "type": "synonym", "evidence": [ { "id": "A0AAA9TSG6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TSG6/entry#names_and_taxonomy" } ] }, { "name": "Sorting nexin-26", "type": "synonym", "evidence": [ { "id": "A0AAA9TSG6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TSG6/entry#names_and_taxonomy" } ] }, { "name": "Tc10/CDC42 GTPase-activating protein", "type": "synonym", "evidence": [ { "id": "A0AAA9TSG6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TSG6/entry#names_and_taxonomy" } ] }, { "name": "rho GTPase-activating protein 33 isoform X3", "type": "synonym", "evidence": [ { "id": "XP_010813165", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_010813165" } ] } ], "function": [ { "annotation": "May be involved in several stages of intracellular trafficking. Could play an important role in the regulation of glucose transport by insulin. May act as a downstream effector of RHOQ/TC10 in the regulation of insulin-stimulated glucose transport.", "evidence": [ { "database": "UniProtKB", "id": "A0AAA9TSG6", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TSG6#function" }, { "database": "UniProtKB", "id": "ARBA00053764", "url": "https://www.uniprot.org/uniprotkb/ARBA00053764#function" }, { "database": "UniProtKB", "id": "F1MS60", "url": "https://www.uniprot.org/uniprotkb/F1MS60#function" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Bos taurus", "taxid": 9913, "evidence": [ { "database": "UniProtKB", "id": "A0AAA9TSG6", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TSG6" } ], "common_name": "Bovine", "glygen_name": "Bovine", "reference_species": "Bos taurus [9913]" } ], "gene": [ { "name": "ARHGAP33", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TSG6", "locus": { "chromosome": "18", "start_pos": 46500731, "end_pos": 46487512, "strand": "-", "evidence": [ { "database": "Ensembl Gene", "id": "ENSBTAG00000009714", "url": "https://www.ensembl.org/id/ENSBTAG00000009714" } ] } } ], "crossref": [ { "id": "ENSBTAG00000009714", "url": "https://bgee.org/?page=gene&gene_id=ENSBTAG00000009714", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "cd04384", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd04384", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "cd11835", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd11835", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "100138767", "url": "https://www.ncbi.nlm.nih.gov/gene/100138767", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR000198", "url": "https://www.ebi.ac.uk/interpro/entry/IPR000198", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR001452", "url": "https://www.ebi.ac.uk/interpro/entry/IPR001452", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR008936", "url": "https://www.ebi.ac.uk/interpro/entry/IPR008936", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR036028", "url": "https://www.ebi.ac.uk/interpro/entry/IPR036028", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR036871", "url": "https://www.ebi.ac.uk/interpro/entry/IPR036871", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR051576", "url": "https://www.ebi.ac.uk/interpro/entry/IPR051576", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "bta:100138767", "url": "https://www.genome.jp/dbget-bin/www_bget?bta:100138767", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "PTHR15729", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR15729", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR15729:SF11", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR15729:SF11", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00620", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00620", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF07653", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF07653", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "R-BTA-9013148", "url": "https://www.reactome.org/PathwayBrowser/#R-BTA-9013148", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "R-BTA-9013406", "url": "https://www.reactome.org/PathwayBrowser/#R-BTA-9013406", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "XP_010813165", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_010813165", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0AAA9TSG6", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TSG6", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0AAA9TSG6-1", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TSG6-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "F1MS60", "url": "https://www.uniprot.org/uniprotkb/F1MS60", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "F1MS60-1", "url": "https://www.uniprot.org/uniprotkb/F1MS60-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MVARSNDSLDGPGEGSVQPLPPTGGPSVKGKPGKRLSAPRGPFPRLADCAHFHYENVDFGHIQLLLSPERDGPNVSGENELVFGVQVTCQGRSWPVLRSYDDFRSLDAHLHRCIFDRRFSCLPELPPPPEGARAAQMLVPLLLQYLETLSGLVDSNLNCGPVLTWMELDNHGRRLLLSEEASLNIPAVAAAHVVKRYTAQAPDELSFEVGDIVSVIDMPPTEDRSWWRGKRGFQVGFFPSECVELFTERPGPGLKGDADGPPCGVLASQGASSLTSAVPRPRGKLAGLLRTFMRSRPSRQRLRQRGILRQRVFGCDLGEHLSNSGQDVPQVLRCCSEFIEAHGVVDGIYRLSGVSSNIQRLRHEFDSERIPELSGPAFLQDIHSVSSLCKLYFRELPNPLLTYQLYGKFSEAMSVPGEEERLVRVHDVIQQLPPPHYRTLEYLLRHLARMARHSANTSMHARNLAIVWAPNLLRSMELESVGLGGAAAFREVRVQSVVVEFLLTHVDVLFSDTFTSAGLDPAGRCLLPRPKSLAGSGPSTRLLTLEEAQARTQGRLGTPTEPTTSKAPTSPVERRKGERGEKQRKPGGSSWKTFFALGRGPSIPRKKPLPWLGGTRARPQPSGCRPDTVTLRSAKSEESLSSQASGAGLQRLHRLRRPHSSSDAFPVGPAPAGSCESLSSSESTESSSESSSSSSSESSAAGLGVLSGSPSHRTSAWLDDGDELDFSPPRCLEGLRGLDFDPLTFRCSSPTPGDPAPPASPAPPAPASAFPPRATPQALSPRGPTSPASPAALDISEPLSVSVPPAVLELLGAGGTPASATPTPALSPSPGLCPHLIPLLLRGAEAQLSDTCQQEICSKLALPGPRGAQGQHGAGMDSPLLPPPLSLLRPGGAPPPPPKNPARLMALALAERAQQVAQRQSQQEQGSTPSAPQSPFRRSLSLEVGGEPPGTSGSGPPPHPLAHPSGWAPGPPPSLPRQQSDGSLVRSQRPTGTSRRAPRGPAQVSAQLRMGGGCGAAPEMAAQFLCSVPQQVPTPGFFSAPRECLPPFLGVPKPGLYPLGSPSFQPSSPAPVWRSPLVPPAPLDRGENLYYEIEAGEGSPYSGPTRSWSPLRSMPPDRLNASYGMLGQSPPLHRSPDFLLSYPPPSCFPHDHLGYSAPQHSARRPTRPEPLYVNLALGPRGPSPASSSSSSPPAHPRSRSDPGPPAPRLPQKQRAPWGHHTPHRVPGPWGPPDPLPYRAAPPAYGRGGEHHRGSLYRNGGQGREGAGPPPPYPTPSWSFHPESQTQSYC", "length": 1289, "header": "tr|A0AAA9TSG6-1|A0AAA9TSG6_BOVIN Isoform 1 of Rho GTPase-activating protein 33 OS=Bos taurus OX=9913 GN=ARHGAP33 PE=3 SV=1 CANONICAL=A0AAA9TSG6-1" }, "isoforms": [ { "isoform_ac": "A0AAA9TSG6-1", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TSG6/entry", "sequence": { "sequence": "MVARSNDSLDGPGEGSVQPLPPTGGPSVKGKPGKRLSAPRGPFPRLADCAHFHYENVDFGHIQLLLSPERDGPNVSGENELVFGVQVTCQGRSWPVLRSYDDFRSLDAHLHRCIFDRRFSCLPELPPPPEGARAAQMLVPLLLQYLETLSGLVDSNLNCGPVLTWMELDNHGRRLLLSEEASLNIPAVAAAHVVKRYTAQAPDELSFEVGDIVSVIDMPPTEDRSWWRGKRGFQVGFFPSECVELFTERPGPGLKGDADGPPCGVLASQGASSLTSAVPRPRGKLAGLLRTFMRSRPSRQRLRQRGILRQRVFGCDLGEHLSNSGQDVPQVLRCCSEFIEAHGVVDGIYRLSGVSSNIQRLRHEFDSERIPELSGPAFLQDIHSVSSLCKLYFRELPNPLLTYQLYGKFSEAMSVPGEEERLVRVHDVIQQLPPPHYRTLEYLLRHLARMARHSANTSMHARNLAIVWAPNLLRSMELESVGLGGAAAFREVRVQSVVVEFLLTHVDVLFSDTFTSAGLDPAGRCLLPRPKSLAGSGPSTRLLTLEEAQARTQGRLGTPTEPTTSKAPTSPVERRKGERGEKQRKPGGSSWKTFFALGRGPSIPRKKPLPWLGGTRARPQPSGCRPDTVTLRSAKSEESLSSQASGAGLQRLHRLRRPHSSSDAFPVGPAPAGSCESLSSSESTESSSESSSSSSSESSAAGLGVLSGSPSHRTSAWLDDGDELDFSPPRCLEGLRGLDFDPLTFRCSSPTPGDPAPPASPAPPAPASAFPPRATPQALSPRGPTSPASPAALDISEPLSVSVPPAVLELLGAGGTPASATPTPALSPSPGLCPHLIPLLLRGAEAQLSDTCQQEICSKLALPGPRGAQGQHGAGMDSPLLPPPLSLLRPGGAPPPPPKNPARLMALALAERAQQVAQRQSQQEQGSTPSAPQSPFRRSLSLEVGGEPPGTSGSGPPPHPLAHPSGWAPGPPPSLPRQQSDGSLVRSQRPTGTSRRAPRGPAQVSAQLRMGGGCGAAPEMAAQFLCSVPQQVPTPGFFSAPRECLPPFLGVPKPGLYPLGSPSFQPSSPAPVWRSPLVPPAPLDRGENLYYEIEAGEGSPYSGPTRSWSPLRSMPPDRLNASYGMLGQSPPLHRSPDFLLSYPPPSCFPHDHLGYSAPQHSARRPTRPEPLYVNLALGPRGPSPASSSSSSPPAHPRSRSDPGPPAPRLPQKQRAPWGHHTPHRVPGPWGPPDPLPYRAAPPAYGRGGEHHRGSLYRNGGQGREGAGPPPPYPTPSWSFHPESQTQSYC", "length": 1289, "header": "tr|A0AAA9TSG6-1|A0AAA9TSG6_BOVIN Isoform 1 of Rho GTPase-activating protein 33 OS=Bos taurus OX=9913 GN=ARHGAP33 PE=3 SV=1 CANONICAL=A0AAA9TSG6-1" }, "locus": { "chromosome": "18", "start_pos": 46500283, "end_pos": 46487653, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000109668.2", "url": "https://www.ensembl.org/id/ENSBTAT00000109668.2" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000100292.1", "url": "https://www.ensembl.org/id/ENSBTAP00000100292.1" } ] } }, { "isoform_ac": "F1MS60-1", "url": "https://www.uniprot.org/uniprotkb/F1MS60/entry", "sequence": { "sequence": "MGWRGTDPRARSNDSLDGPGEGSVQPLPPTGGPSVKGKPGKRLSAPRGPFPRLADCAHFHYENVDFGHIQLLLSPERDGPNVSGENELVFGVQVTCQGRSWPVLRSYDDFRSLDAHLHRCIFDRRFSCLPELPPPPEGARAAQMLVPLLLQYLETLSGLVDSNLNCGPVLTWMELDNHGRRLLLSEEASLNIPAVAAAHVVKRYTAQAPDELSFEVGDIVSVIDMPPTEDRSWWRGKRGFQVGFFPSECVELFTERPGPGLKGDADGPPCGVLASQGASSLTSAVPRPRGKLAGLLRTFMRSRPSRQRLRQRGILRQRVFGCDLGEHLSNSGQDVPQVLRCCSEFIEAHGVVDGIYRLSGVSSNIQRLRHEFDSERIPELSGPAFLQDIHSVSSLCKLYFRELPNPLLTYQLYGKFSEAMSVPGEEERLVRVHDVIQQLPPPHYRTLEYLLRHLARMARHSANTSMHARNLAIVWAPNLLRSMELESVGLGGAAAFREVRVQSVVVEFLLTHVDVLFSDTFTSAGLDPAGRCLLPRPKSLAGSGPSTRLLTLEEAQARTQGRLGTPTEPTTSKAPTSPVERRKGERGEKQRKPGGSSWKTFFALGRGPSIPRKKPLPWLGGTRARPQPSGCRPDTVTLRSAKSEESLSSQASGAGLQRLHRLRRPHSSSDAFPVGPAPAGSCESLSSSESTESSSESSSSSSSESSAAGLGVLSGSPSHRTSAWLDDGDELDFSPPRCLEGLRGLDFDPLTFRCSSPTPGDPAPPASPAPPAPASAFPPRATPQALSPRGPTSPASPAALDISEPLSVSVPPAVLELLGAGGTPASATPTPALSPSPGLCPHLIPLLLRGAEAQLSDTCQQEICSKLALPGPRGAQGQHGAGMDSPLLPPPLSLLRPGGAPPPPPKNPARLMALALAERAQQVAQRQSQQEQGSTPSAPQSPFRRSLSLEVGGEPPGTSGSGPPPHPLAHPSGWAPGPPPSLPRQQSDGSLVRSQRPTGTSRRAPRGPAQVPTPGFFSAPRECLPPFLGVPKPGLYPLGSPSFQPSSPAPVWRSPLVPPAPLDRGENLYYEIEAGEGSPYSGPTRSWSPLRSMPPDRLNASYGMLGQSPPLHRSPDFLLSYPPPSCFPHDHLGYSAPQHSARRPTRPEPLYVNLALGPRGPSPASSSSSSPPAHPRSRSDPGPPAPRLPQKQRAPWGHHTPHRVPGPWGPPDPLPYRAAPPAYGRGGEHHRGSLYRNGGQGREGAGPPPPYPTPSWSFHPESQTQSYC", "length": 1268, "header": "tr|F1MS60-1|F1MS60_BOVIN Computationally mapped isoform of Rho GTPase-activating protein 33 OS=Bos taurus OX=9913 GN=ARHGAP33 PE=3 SV=4 CANONICAL=A0AAA9TSG6-1" }, "locus": { "chromosome": "18", "start_pos": 46500283, "end_pos": 46488482, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000012813.8", "url": "https://www.ensembl.org/id/ENSBTAT00000012813.8" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000012813.7", "url": "https://www.ensembl.org/id/ENSBTAP00000012813.7" } ] } } ], "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "other", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 1034, "start_aa": "Thr", "end_pos": 1034, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr1034", "evidence": [ { "id": "", "database": "GlyGen", "url": "https://data.glygen.org/" } ], "filter_code": "000000000000000010000.00000000001000.0.01000" }, { "glytoucan_ac": "", "type": "O-linked", "subtype": "other", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 1274, "start_aa": "Thr", "end_pos": 1274, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr1274", "evidence": [ { "id": "", "database": "GlyGen", "url": "https://data.glygen.org/" } ], "filter_code": "000000000000000010000.00000000001000.0.01000" }, { "glytoucan_ac": "", "type": "O-linked", "subtype": "other", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 751, "start_aa": "Thr", "end_pos": 751, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr751", "evidence": [ { "id": "", "database": "GlyGen", "url": "https://data.glygen.org/" } ], "filter_code": "000000000000000010000.00000000001000.0.01000" }, { "glytoucan_ac": "", "type": "O-linked", "subtype": "other", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 785, "start_aa": "Thr", "end_pos": 785, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr785", "evidence": [ { "id": "", "database": "GlyGen", "url": "https://data.glygen.org/" } ], "filter_code": "000000000000000010000.00000000001000.0.01000" }, { "glytoucan_ac": "", "type": "O-linked", "subtype": "other", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 816, "start_aa": "Thr", "end_pos": 816, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr816", "evidence": [ { "id": "", "database": "GlyGen", "url": "https://data.glygen.org/" } ], "filter_code": "000000000000000010000.00000000001000.0.01000" }, { "glytoucan_ac": "", "type": "O-linked", "subtype": "other", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 821, "start_aa": "Thr", "end_pos": 821, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr821", "evidence": [ { "id": "", "database": "GlyGen", "url": "https://data.glygen.org/" } ], "filter_code": "000000000000000010000.00000000001000.0.01000" }, { "glytoucan_ac": "", "type": "O-linked", "subtype": "other", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 823, "start_aa": "Thr", "end_pos": 823, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr823", "evidence": [ { "id": "", "database": "GlyGen", "url": "https://data.glygen.org/" } ], "filter_code": "000000000000000010000.00000000001000.0.01000" } ], "phosphorylation": [], "glycation": [], "keywords": [ "glycoprotein", "glycoprotein_predicted" ], "publication": [], "pathway": [ { "id": "bta:100138767", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?bta:100138767", "resource": "KEGG Pathway" }, { "id": "R-BTA-9013148", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-BTA-9013148", "resource": "Reactome", "description": "CDC42 GTPase cycle" }, { "id": "R-BTA-9013406", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-BTA-9013406", "resource": "Reactome", "description": "RHOQ GTPase cycle" } ], "orthologs": [], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 5, "go_terms": [ { "name": "glutamatergic synapse", "id": "GO:0098978", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0098978", "evidence": [ { "database": "UniProtKB", "id": "A0AAA9TSG6", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TSG6" } ], "pmid": "" }, { "name": "cytoplasm", "id": "GO:0005737", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005737", "evidence": [ { "database": "UniProtKB", "id": "A0AAA9TSG6", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TSG6" } ], "pmid": "" }, { "name": "plasma membrane", "id": "GO:0005886", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005886", "evidence": [ { "database": "UniProtKB", "id": "A0AAA9TSG6", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TSG6" } ], "pmid": "" }, { "name": "protein-containing complex", "id": "GO:0032991", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0032991", "evidence": [ { "database": "UniProtKB", "id": "A0AAA9TSG6", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TSG6" } ], "pmid": "" }, { "name": "postsynaptic density", "id": "GO:0014069", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0014069", "evidence": [ { "database": "UniProtKB", "id": "A0AAA9TSG6", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TSG6" } ], "pmid": "" } ] }, { "name": "Molecular Function", "total": 3, "go_terms": [ { "name": "GTPase activator activity", "id": "GO:0005096", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005096", "evidence": [ { "database": "UniProtKB", "id": "A0AAA9TSG6", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TSG6" } ], "pmid": "" }, { "name": "protein kinase binding", "id": "GO:0019901", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0019901", "evidence": [ { "database": "UniProtKB", "id": "A0AAA9TSG6", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TSG6" } ], "pmid": "" }, { "name": "phosphatidylinositol binding", "id": "GO:0035091", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0035091", "evidence": [ { "database": "UniProtKB", "id": "A0AAA9TSG6", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TSG6" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 5, "go_terms": [ { "name": "signal transduction", "id": "GO:0007165", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007165", "evidence": [ { "database": "UniProtKB", "id": "A0AAA9TSG6", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TSG6" } ], "pmid": "" }, { "name": "protein transport", "id": "GO:0015031", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0015031", "evidence": [ { "database": "UniProtKB", "id": "A0AAA9TSG6", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TSG6" } ], "pmid": "" }, { "name": "regulation of postsynapse assembly", "id": "GO:0150052", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0150052", "evidence": [ { "database": "UniProtKB", "id": "A0AAA9TSG6", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TSG6" } ], "pmid": "" }, { "name": "small GTPase-mediated signal transduction", "id": "GO:0007264", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007264", "evidence": [ { "database": "UniProtKB", "id": "A0AAA9TSG6", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TSG6" } ], "pmid": "" }, { "name": "regulation of dendritic spine morphogenesis", "id": "GO:0061001", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0061001", "evidence": [ { "database": "UniProtKB", "id": "A0AAA9TSG6", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TSG6" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 1120, "end_pos": 1122, "annotation": "n_glycosylation_sequon" }, { "start_pos": 456, "end_pos": 458, "annotation": "n_glycosylation_sequon" }, { "start_pos": 6, "end_pos": 8, "annotation": "n_glycosylation_sequon" }, { "start_pos": 74, "end_pos": 76, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A0AAA9TSG6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TSG6" }, { "id": "PS50238", "database": "PROSITE", "url": "https://prosite.expasy.org/PS50238" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "Rho-GAP", "eco_id": "ECO_0000259", "start_pos": 315, "end_pos": 510, "start_aa": "Cys", "end_aa": "Phe", "glycosite_overlap": [] }, { "evidence": [ { "id": "A0AAA9TSG6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TSG6" }, { "id": "PS50002", "database": "PROSITE", "url": "https://prosite.expasy.org/PS50002" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "SH3", "eco_id": "ECO_0000259", "start_pos": 186, 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"https://www.uniprot.org/uniprotkb/A0AAA9TSM5-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "F1N0Q1", "url": "https://www.uniprot.org/uniprotkb/F1N0Q1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "F1N0Q1-1", "url": "https://www.uniprot.org/uniprotkb/F1N0Q1-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MEPKEAPGKENMGTKKKNLPFLRPRLYMLERRKTDTVVESSVPGDHSGTLRRSQSDRSEYNQKLQEKMTPQAGCSTAETLTQEDEHQIQRMMAKRAKIIKELIQTEKDYLNDLELCVQEVVQPLRNKQVDRLDVDSLFSNIESVHQISAKLLSLLEEATTDVEPAMQVIGEVFLQIKGPLEDIYKIYCYHHDEAHSVLESYEKEEELKQHLSLCIQSLKNIYMQQGKPNLLDMGSLMIKPIQRVMKYPLLLCELRNSTPSSHPDFQALEDAYAAVKHINVNINELKRRKDLVLKYKKNDEEESLKDKLSKLNIHSISKKSKRVTNHLKILTRGESQVKDNTFNREEKLFRSLEKTVRHCVKNISSCLQHIQDAMPLALQNMMELQEISHNKDEEESSYSESPSNAPNPSEDFAAHLQKLVLTPLSALLSLFPGPQKLIQKRYDKLLDYNSYLQRAAADESDLAKREYEALNAQLVEELQVFNLAARKILLNCLCSFVTLLRDLMIVAQRVHTTTVPVPQLASSISEIQNRVLEEVQNLNFVKDNSATFIERKLSFEKKKPVQTLPEVPRQTDTHRSKLLSTYSTEELYQAKRKCNATQEYDINLLEGELVAVIEQKDPLGSTSRWLVDTGIIKGYVYSSFLKPYNPARVQKVDAENRFCDDDFDNISLFVSSRPARDSVAGTPEGSISGSSSSLSGTCGKSETNGTDADSLQEADEQIFYAVHAFQARSDHELSLQEYQRVHILRFCDLSGNKEWWLAEVQGQKGYVPANYLGKMTYA", "length": 778, "header": "tr|A0AAA9TSM5-1|A0AAA9TSM5_BOVIN Isoform 1 of Rho guanine nucleotide exchange factor 38 OS=Bos taurus OX=9913 GN=ARHGEF38 PE=4 SV=1 CANONICAL=A0AAA9TSM5-1" }, "isoforms": [ { "isoform_ac": "A0AAA9TSM5-1", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TSM5/entry", "sequence": { "sequence": "MEPKEAPGKENMGTKKKNLPFLRPRLYMLERRKTDTVVESSVPGDHSGTLRRSQSDRSEYNQKLQEKMTPQAGCSTAETLTQEDEHQIQRMMAKRAKIIKELIQTEKDYLNDLELCVQEVVQPLRNKQVDRLDVDSLFSNIESVHQISAKLLSLLEEATTDVEPAMQVIGEVFLQIKGPLEDIYKIYCYHHDEAHSVLESYEKEEELKQHLSLCIQSLKNIYMQQGKPNLLDMGSLMIKPIQRVMKYPLLLCELRNSTPSSHPDFQALEDAYAAVKHINVNINELKRRKDLVLKYKKNDEEESLKDKLSKLNIHSISKKSKRVTNHLKILTRGESQVKDNTFNREEKLFRSLEKTVRHCVKNISSCLQHIQDAMPLALQNMMELQEISHNKDEEESSYSESPSNAPNPSEDFAAHLQKLVLTPLSALLSLFPGPQKLIQKRYDKLLDYNSYLQRAAADESDLAKREYEALNAQLVEELQVFNLAARKILLNCLCSFVTLLRDLMIVAQRVHTTTVPVPQLASSISEIQNRVLEEVQNLNFVKDNSATFIERKLSFEKKKPVQTLPEVPRQTDTHRSKLLSTYSTEELYQAKRKCNATQEYDINLLEGELVAVIEQKDPLGSTSRWLVDTGIIKGYVYSSFLKPYNPARVQKVDAENRFCDDDFDNISLFVSSRPARDSVAGTPEGSISGSSSSLSGTCGKSETNGTDADSLQEADEQIFYAVHAFQARSDHELSLQEYQRVHILRFCDLSGNKEWWLAEVQGQKGYVPANYLGKMTYA", "length": 778, "header": "tr|A0AAA9TSM5-1|A0AAA9TSM5_BOVIN Isoform 1 of Rho guanine nucleotide exchange factor 38 OS=Bos taurus OX=9913 GN=ARHGEF38 PE=4 SV=1 CANONICAL=A0AAA9TSM5-1" }, "locus": { "chromosome": "6", "start_pos": 19635723, "end_pos": 19485471, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000102725.1", "url": "https://www.ensembl.org/id/ENSBTAT00000102725.1" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000099482.1", "url": "https://www.ensembl.org/id/ENSBTAP00000099482.1" } ] } }, { "isoform_ac": "F1N0Q1-1", "url": "https://www.uniprot.org/uniprotkb/F1N0Q1/entry", "sequence": { "sequence": "MEPKEAPGKENMGTKKKNLPFLRPRLYMLERRKTDTVVESSVPGDHSGTLRRSQSDRSEYNQKLQEKMTPQAGCSTAETLTQEDEHQIQRMMAKRAKIIKELIQTEKDYLNDLELCVQEVVQPLRNKQVDRLDVDSLFSNIESVHQISAKLLSLLEEATTDVEPAMQVIGEVFLQIKGPLEDIYKIYCYHHDEAHSVLESYEKEEELKQHLSLCIQSLKNIYMQQGKPNLLDMGSLMIKPIQRVMKYPLLLCELRNSTPSSHPDFQALEDAYAAVKHINVNINELKRRKDLVLKYKKNDEEESLKDKLSKLNIHSISKKSKRVTNHLKILTRGESQVKDNTFNREEKLFRSLEKTVRHCVKNISSCLQHIQDAMPLALQNMMELQEISHNKDEEESSYSESPSNAPNPSEDFAAHLQKLVLTPLSALLSLFPGPQKLIQKRYDKLLDYNSYLQRAAADESDLAKREYEALNAQLVEELQVFNLAARKILLNCLCSFVTLLRDLMIVAQRVHTTTVPVPQLASSISEIQNRVLEEVQNLNFVKDNSATFIERKLSFEKKKPVQTLPEVPRQTDTHRSKLLSTYSTEELYQAKRKCNATQEYDINLLEGELVAVIEQKDPLGSTSRWLVDTGIIKGYVYSSFLKPYNPARVQKVDAENRFCDDDFDNISLFVSSRPARDSVAGTPEGSISGSSSSLSGTCGKSETNGTDADSLQEADEQGFNSLSLFPQMRKRRQ", "length": 733, "header": "tr|F1N0Q1-1|A0AAA9TSM5_BOVIN Computationally mapped isoform of Rho guanine nucleotide exchange factor 38 OS=Bos taurus OX=9913 GN=ARHGEF38 PE=4 SV=3 CANONICAL=A0AAA9TSM5-1" }, "locus": { "chromosome": "6", "start_pos": 19635723, "end_pos": 19494463, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000011590.5", "url": "https://www.ensembl.org/id/ENSBTAT00000011590.5" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000011590.5", "url": "https://www.ensembl.org/id/ENSBTAP00000011590.5" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [ { "id": "bta:618404", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?bta:618404", "resource": "KEGG Pathway" }, { "id": "R-BTA-416482", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-BTA-416482", "resource": "Reactome", "description": "G alpha (12/13) signalling events" } ], "orthologs": [], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 1, "go_terms": [ { "name": "cytoplasm", "id": "GO:0005737", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005737", "evidence": [ { "database": "UniProtKB", "id": "A0AAA9TSM5", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TSM5" } ], "pmid": "" } ] }, { "name": "Molecular Function", "total": 1, "go_terms": [ { "name": "guanyl-nucleotide exchange factor activity", "id": "GO:0005085", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005085", "evidence": [ { "database": "UniProtKB", "id": "A0AAA9TSM5", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TSM5" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 256, "end_pos": 258, "annotation": "n_glycosylation_sequon" }, { "start_pos": 362, "end_pos": 364, "annotation": "n_glycosylation_sequon" }, { "start_pos": 595, "end_pos": 597, "annotation": "n_glycosylation_sequon" }, { "start_pos": 665, "end_pos": 667, "annotation": "n_glycosylation_sequon" }, { "start_pos": 704, "end_pos": 706, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A0AAA9TSM5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TSM5" }, { "id": "PS51021", "database": "PROSITE", "url": "https://prosite.expasy.org/PS51021" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "BAR", "eco_id": "ECO_0000259", "start_pos": 327, "end_pos": 537, "start_aa": "Leu", "end_aa": "Asn", "glycosite_overlap": [] }, { "evidence": [ { "id": "A0AAA9TSM5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TSM5" }, { "id": "PS50010", "database": "PROSITE", "url": "https://prosite.expasy.org/PS50010" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "DH", "eco_id": "ECO_0000259", "start_pos": 94, "end_pos": 285, "start_aa": "Lys", "end_aa": "Leu", "glycosite_overlap": [] }, { "evidence": [ { "id": "A0AAA9TSM5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TSM5" }, { "id": "PS50002", "database": "PROSITE", "url": "https://prosite.expasy.org/PS50002" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "SH3", "eco_id": "ECO_0000259", "start_pos": 583, "end_pos": 646, "start_aa": "Ser", "end_aa": "Pro", "glycosite_overlap": [] } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 256, "end_pos": 258 }, { "start_pos": 362, "end_pos": 364 }, { "start_pos": 595, "end_pos": 597 }, { "start_pos": 665, "end_pos": 667 }, { "start_pos": 704, "end_pos": 706 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ], "tool_support": { "graph_view": "yes" } }, { "uniprot_canonical_ac": "A0AAA9TSN5-1", "uniprot_ac": "A0AAA9TSN5", "uniprot_id": "A0AAA9TSN5_BOVIN", "mass": { "chemical_mass": 91164.0, "monoisotopic_mass": 91164.0 }, "refseq": {}, "gene_names": [ { "name": "NHLRC2", "type": "recommended", "evidence": [ { "id": "A0AAA9TSN5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TSN5" } ] } ], "protein_names": [ { "name": "NHL repeat-containing protein 2", "type": "recommended", "evidence": [ { "id": "A0AAA9TSN5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TSN5/entry#names_and_taxonomy" } ] } ], "function": [ { "annotation": "Required for normal embryonic development.", "evidence": [ { "database": "UniProtKB", "id": "A0AAA9TSN5", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TSN5#function" }, { "database": "UniProtKB", "id": "ARBA00057428", "url": "https://www.uniprot.org/uniprotkb/ARBA00057428#function" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Bos taurus", "taxid": 9913, "evidence": [ { "database": "UniProtKB", "id": "A0AAA9TSN5", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TSN5" } ], "common_name": "Bovine", "glygen_name": "Bovine", "reference_species": "Bos taurus [9913]" } ], "gene": [ { "name": "NHLRC2", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TSN5", "locus": { "chromosome": "26", "start_pos": 34362842, "end_pos": 34306364, "strand": "-", "evidence": [ { "database": "Ensembl Gene", "id": "ENSBTAG00000003690", "url": "https://www.ensembl.org/id/ENSBTAG00000003690" } ] } } ], "crossref": [ { "id": "A0AAA9TSN5", "url": "https://alphafold.ebi.ac.uk/entry/A0AAA9TSN5", "database": "AlphaFoldDB", "categories": [] }, { "id": "cd03012", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd03012", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "cd14951", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd14951", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "IPR000033", "url": "https://www.ebi.ac.uk/interpro/entry/IPR000033", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR001258", "url": "https://www.ebi.ac.uk/interpro/entry/IPR001258", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR011042", "url": "https://www.ebi.ac.uk/interpro/entry/IPR011042", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR012336", "url": "https://www.ebi.ac.uk/interpro/entry/IPR012336", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR036249", "url": "https://www.ebi.ac.uk/interpro/entry/IPR036249", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR045302", "url": "https://www.ebi.ac.uk/interpro/entry/IPR045302", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "PTHR46388", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR46388", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR46388:SF2", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR46388:SF2", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF01436", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF01436", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF13905", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF13905", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "A0AAA9TSN5", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TSN5", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0AAA9TSN5-1", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TSN5-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0ABI0NYW8", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NYW8", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0ABI0NYW8-1", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NYW8-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MTPTGSTSCLGIRDGKASGGGPHSPPFLRAGSEGAANTARSAKAIGAPTPHPPTPPLLRAGAHLPPSPPPPPCEELQLRPLPPDTPRPPGPRVRSCTFTALLDRPAGWAAAPGPSGENMAAPGARSCNLSGLLPAQTSLEYALLDAVTQEEKDGLVYQYLQKVDGWEQDLLVPEFPEGLEWLNTEEPISVYKDLCGKVVILDFFTYCCINCIHLLPDLHALEHTYSDKDGLLIVGVHSAKFPNEKVLDNIRSAVLRYNITHPVVNDADASLWQELEVSCWPTLIILGPRGNMLFSLIGEGHKEKLFLYTSIALKYYKDRGQIRANKIGIKLYKDSLPPSPLLFPGKITVDHVSNRLVIADTGHHRILVVWKNGQIQYSIGGPNPGRKDGIFSESSFNSPQGVAIMNNIIYVADTENHLIRKIDLEAEMVSTVAGIGIQGTDKEGGAKGDEQPISSPWDVVFGRSGPEVQRDNILWIAMAGTHQIWALLLDCGRLPKKNELKKGTCLRFAGSGNEENRNNAYPHKAGFAQPSGLSLASEGPWSCLFVADSESSTVRTVSLKDGAVKHLVGGERDPMNLFAFGDVDGVGINARLQHPLGVTWDQKRNLLYVADSYNHKIKVVDPKTKNCTTLAGTGNASNMIGSSFTDSTFNEPGGLCIGENGQLLYVADTNNHQIKVLDLETKTVSVFPVFRSENAVVDGPCLAGKPKTLPKLPKSAPGIRLAPVAASPGQTLQFKLRLDLPSGTKLTEGASSCWFLSAEGNEWLLQGQIPSGEIESISNQPTISLQIPGDCLSLEAILSISVFLYYCSSDSSACMMKGILFSQPLQITDTQQDCIPPVELKYIF", "length": 844, "header": "tr|A0AAA9TSN5-1|A0AAA9TSN5_BOVIN Isoform 1 of NHL repeat-containing protein 2 OS=Bos taurus OX=9913 GN=NHLRC2 PE=4 SV=1 CANONICAL=A0AAA9TSN5-1" }, "isoforms": [ { "isoform_ac": "A0AAA9TSN5-1", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TSN5/entry", "sequence": { "sequence": "MTPTGSTSCLGIRDGKASGGGPHSPPFLRAGSEGAANTARSAKAIGAPTPHPPTPPLLRAGAHLPPSPPPPPCEELQLRPLPPDTPRPPGPRVRSCTFTALLDRPAGWAAAPGPSGENMAAPGARSCNLSGLLPAQTSLEYALLDAVTQEEKDGLVYQYLQKVDGWEQDLLVPEFPEGLEWLNTEEPISVYKDLCGKVVILDFFTYCCINCIHLLPDLHALEHTYSDKDGLLIVGVHSAKFPNEKVLDNIRSAVLRYNITHPVVNDADASLWQELEVSCWPTLIILGPRGNMLFSLIGEGHKEKLFLYTSIALKYYKDRGQIRANKIGIKLYKDSLPPSPLLFPGKITVDHVSNRLVIADTGHHRILVVWKNGQIQYSIGGPNPGRKDGIFSESSFNSPQGVAIMNNIIYVADTENHLIRKIDLEAEMVSTVAGIGIQGTDKEGGAKGDEQPISSPWDVVFGRSGPEVQRDNILWIAMAGTHQIWALLLDCGRLPKKNELKKGTCLRFAGSGNEENRNNAYPHKAGFAQPSGLSLASEGPWSCLFVADSESSTVRTVSLKDGAVKHLVGGERDPMNLFAFGDVDGVGINARLQHPLGVTWDQKRNLLYVADSYNHKIKVVDPKTKNCTTLAGTGNASNMIGSSFTDSTFNEPGGLCIGENGQLLYVADTNNHQIKVLDLETKTVSVFPVFRSENAVVDGPCLAGKPKTLPKLPKSAPGIRLAPVAASPGQTLQFKLRLDLPSGTKLTEGASSCWFLSAEGNEWLLQGQIPSGEIESISNQPTISLQIPGDCLSLEAILSISVFLYYCSSDSSACMMKGILFSQPLQITDTQQDCIPPVELKYIF", "length": 844, "header": "tr|A0AAA9TSN5-1|A0AAA9TSN5_BOVIN Isoform 1 of NHL repeat-containing protein 2 OS=Bos taurus OX=9913 GN=NHLRC2 PE=4 SV=1 CANONICAL=A0AAA9TSN5-1" }, "locus": { "chromosome": "26", "start_pos": 34361269, "end_pos": 34306563, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000101866.2", "url": "https://www.ensembl.org/id/ENSBTAT00000101866.2" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000100062.1", "url": "https://www.ensembl.org/id/ENSBTAP00000100062.1" } ] } }, { "isoform_ac": "A0ABI0NYW8-1", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NYW8/entry", "sequence": { "sequence": "MAAPGARSCNLSGLLPAQTSLEYALLDAVTQEEKDGLVYQYLQKVDGWEQDLLVPEFPEDGLLIVGVHSAKFPNEKVLDNIRSAVLRYNITHPVVNDADASLWQELEVSCWPTLIILGPRGNMLFSLIGEGHKEKLFLYTSIALKYYKDRGQIRANKIGIKLYKDSLPPSPLLFPGKITVDHVSNRLVIADTGHHRILVVWKNGQIQYSIGGPNPGRKDGIFSESSFNSPQGVAIMNNIIYVADTENHLIRKIDLEAEMVSTVAGIGIQGTDKEGGAKGDEQPISSPWDVVFGRSGPEVQRDNILWIAMAGTHQIWALLLDCGRLPKKNELKKGTCLRFAGSGNEENRNNAYPHKAGFAQPSGLSLASEGPWSCLFVADSESSTVRTVSLKDGAVKHLVGGERDPMNLFAFGDVDGVGINARLQHPLGVTWDQKRNLLYVADSYNHKIKVVDPKTKNCTTLAGTGNASNMIGSSFTDSTFNEPGGLCIGENGQLLYVADTNNHQIKVLDLETKTVSVFPVFRSENAVVDGPCLAGKPKTLPKLPKSAPGIRLAPVAASPGQTLQFKLRLDLPSGTKLTEGASSCWFLSAEGNEWLLQGQIPSGEIESISNQPTISLQIPGDCLSLEAILSISVFLYYCSSDSSACMMKGILFSQPLQITDTQQDCIPPVELKYIF", "length": 675, "header": "tr|A0ABI0NYW8-1|A0ABI0NYW8_BOVIN Computationally mapped isoform of NHL repeat containing 2 OS=Bos taurus OX=9913 GN=NHLRC2 PE=4 SV=1 CANONICAL=A0AAA9TSN5-1" }, "locus": { "chromosome": "26", "start_pos": 34361269, "end_pos": 34307452, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000109391.2", "url": "https://www.ensembl.org/id/ENSBTAT00000109391.2" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000106681.1", "url": "https://www.ensembl.org/id/ENSBTAP00000106681.1" } ] } } ], "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "other", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 54, "start_aa": "Thr", "end_pos": 54, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr54", "evidence": [ { "id": "", "database": "GlyGen", "url": "https://data.glygen.org/" } ], "filter_code": "000000000000000010000.00000000001000.0.01000" } ], "phosphorylation": [], "glycation": [], "keywords": [ "glycoprotein", "glycoprotein_predicted" ], "publication": [], "pathway": [], "orthologs": [], "go_annotation": { 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"database": "Pfam", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF13905" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "Thioredoxin-like fold", "eco_id": "ECO_0000259", "start_pos": 196, "end_pos": 291, "start_aa": "Gly", "end_aa": "Asn", "glycosite_overlap": [] } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [ 54 ], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 128, "end_pos": 130 }, { "start_pos": 258, "end_pos": 260 }, { "start_pos": 626, "end_pos": 628 }, { "start_pos": 635, "end_pos": 637 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 1 }, { "field": "total_sites", "count": 1 }, { "field": "n_linked_sites", "count": 0 }, { "field": 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"table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ], "tool_support": { "graph_view": "yes" } }, { "uniprot_canonical_ac": "A0AAA9TSQ0-1", "uniprot_ac": "A0AAA9TSQ0", "uniprot_id": "A0AAA9TSQ0_BOVIN", "mass": { "chemical_mass": 15884.0, "monoisotopic_mass": 15884.0 }, "refseq": {}, "gene_names": [ { "name": "MRPS14", "type": "recommended", "evidence": [ { "id": "A0AAA9TSQ0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TSQ0" } ] } ], "protein_names": [ { "name": "28S ribosomal protein S14, mitochondrial", "type": "recommended", "evidence": [ { "id": "A0AAA9TSQ0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TSQ0/entry#names_and_taxonomy" } ] } ], "function": [], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Bos taurus", "taxid": 9913, "evidence": [ { "database": "UniProtKB", "id": "A0AAA9TSQ0", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TSQ0" } ], "common_name": "Bovine", "glygen_name": "Bovine", "reference_species": "Bos taurus [9913]" } ], "gene": [ { "name": "MRPS14", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TSQ0", "locus": { "chromosome": "16", "start_pos": 56248731, "end_pos": 56268263, "strand": "+", "evidence": [ { "database": "Ensembl Gene", "id": "ENSBTAG00000001109", "url": "https://www.ensembl.org/id/ENSBTAG00000001109" } ] } } ], "crossref": [ { "id": "A0AAA9TSQ0", "url": "https://alphafold.ebi.ac.uk/entry/A0AAA9TSQ0", "database": "AlphaFoldDB", "categories": [] }, { "id": "IPR001209", "url": "https://www.ebi.ac.uk/interpro/entry/IPR001209", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "PTHR19836", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR19836", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR19836:SF19", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR19836:SF19", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00253", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00253", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "A0AAA9TSQ0", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TSQ0", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0AAA9TSQ0-1", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TSQ0-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0AAF6YHT8", "url": "https://www.uniprot.org/uniprotkb/A0AAF6YHT8", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0AAF6YHT8-1", "url": "https://www.uniprot.org/uniprotkb/A0AAF6YHT8-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MFFWNSLAFSMIPQILAIWSLVVPSSASGQARSYYVDWRMLRDVKRRKMAYEYADERLRINSLRKNTILPKHLQEVADEEIAALPRDSCPVRIRNRCVMTSRPRGVKRRWRLSRIVFRHLADHGQLSGIQRAIW", "length": 134, "header": "tr|A0AAA9TSQ0-1|A0AAA9TSQ0_BOVIN Isoform 1 of 28S ribosomal protein S14, mitochondrial OS=Bos taurus OX=9913 GN=MRPS14 PE=3 SV=1 CANONICAL=A0AAA9TSQ0-1" }, "isoforms": [ { "isoform_ac": "A0AAA9TSQ0-1", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TSQ0/entry", "sequence": { "sequence": "MFFWNSLAFSMIPQILAIWSLVVPSSASGQARSYYVDWRMLRDVKRRKMAYEYADERLRINSLRKNTILPKHLQEVADEEIAALPRDSCPVRIRNRCVMTSRPRGVKRRWRLSRIVFRHLADHGQLSGIQRAIW", "length": 134, "header": "tr|A0AAA9TSQ0-1|A0AAA9TSQ0_BOVIN Isoform 1 of 28S ribosomal protein S14, mitochondrial OS=Bos taurus OX=9913 GN=MRPS14 PE=3 SV=1 CANONICAL=A0AAA9TSQ0-1" }, "locus": { "chromosome": "16", "start_pos": 56256856, "end_pos": 56248997, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000105911.1", "url": "https://www.ensembl.org/id/ENSBTAT00000105911.1" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000099515.1", "url": "https://www.ensembl.org/id/ENSBTAP00000099515.1" } ] } }, { "isoform_ac": "A0AAF6YHT8-1", "url": "https://www.uniprot.org/uniprotkb/A0AAF6YHT8/entry", "sequence": { "sequence": "MATSMLGSLLRIVRQVVPSSASGQARSYYVDWRMLRDVKRRKMAYEYADERLRINSLRKNTILPKHLQVADEEIAALPRDSCPVRIRNRCVMTSRPRGVKRRWRLSRIVFRHLADHGQLSGIQRAIW", "length": 127, "header": "tr|A0AAF6YHT8-1|A0AAF6YHT8_BOVIN Computationally mapped isoform of 28S ribosomal protein S14, mitochondrial OS=Bos taurus OX=9913 GN=MRPS14 PE=3 SV=1 CANONICAL=A0AAA9TSQ0-1" }, "locus": { "chromosome": "16", "start_pos": 56268176, "end_pos": 56248997, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000001465.5", "url": "https://www.ensembl.org/id/ENSBTAT00000001465.5" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000001465.4", "url": "https://www.ensembl.org/id/ENSBTAP00000001465.4" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [], "orthologs": [], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 3, "go_terms": [ { "name": "cytoplasm", "id": "GO:0005737", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005737", "evidence": [ { "database": "UniProtKB", "id": "A0AAA9TSQ0", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TSQ0" } ], "pmid": "" }, { "name": "ribosome", "id": "GO:0005840", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005840", "evidence": [ { "database": "UniProtKB", "id": "A0AAA9TSQ0", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TSQ0" } ], "pmid": "" }, { "name": "ribonucleoprotein complex", "id": "GO:1990904", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:1990904", "evidence": [ { "database": "UniProtKB", "id": "A0AAA9TSQ0", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TSQ0" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 1, "go_terms": [ { "name": "translation", "id": "GO:0006412", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006412", "evidence": [ { "database": "UniProtKB", "id": "A0AAA9TSQ0", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TSQ0" } ], "pmid": "" } ] }, { "name": "Molecular Function", "total": 1, "go_terms": [ { "name": "structural constituent of ribosome", "id": "GO:0003735", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003735", "evidence": [ { "database": "UniProtKB", "id": "A0AAA9TSQ0", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TSQ0" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { 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"https://www.ebi.ac.uk/interpro/entry/IPR014014", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR027417", "url": "https://www.ebi.ac.uk/interpro/entry/IPR027417", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "PTHR47960", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR47960", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00270", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00270", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF00271", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00271", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "A0AAA9TSS4", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TSS4", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0AAA9TSS4-1", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TSS4-1", "database": "UniProtKB", "categories": [ 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GN= PE=4 SV=1 CANONICAL=A0AAA9TSS4-1" }, "locus": { "chromosome": "18", "start_pos": 35479900, "end_pos": 35476802, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000005622.5", "url": "https://www.ensembl.org/id/ENSBTAT00000005622.5" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000005622.4", "url": "https://www.ensembl.org/id/ENSBTAP00000005622.4" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [ "enzyme" ], "publication": [], "pathway": [], "orthologs": [], "go_annotation": { "categories": [ { "name": "Molecular Function", "total": 5, "go_terms": [ { "name": "ATP binding", "id": "GO:0005524", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005524", "evidence": [ { "database": "UniProtKB", "id": "A0AAA9TSS4", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TSS4" } ], "pmid": "" }, { "name": "hydrolase activity", "id": "GO:0016787", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016787", "evidence": [ { "database": "UniProtKB", "id": "A0AAA9TSS4", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TSS4" } ], "pmid": "" }, { "name": "rRNA binding", "id": "GO:0019843", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0019843", "evidence": [ { "database": "UniProtKB", "id": "A0AAA9TSS4", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TSS4" } ], "pmid": "" }, { "name": "RNA helicase activity", "id": "GO:0003724", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003724", "evidence": [ { "database": "UniProtKB", "id": "A0AAA9TSS4", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TSS4" } ], "pmid": "" }, { "name": "nucleic acid binding", "id": "GO:0003676", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003676", "evidence": [ { "database": "UniProtKB", "id": "A0AAA9TSS4", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TSS4" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 3, "go_terms": [ { "name": "nucleolus", "id": "GO:0005730", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005730", "evidence": [ { "database": "UniProtKB", "id": "A0AAA9TSS4", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TSS4" } ], "pmid": "" }, { "name": "mitochondrial nucleoid", "id": "GO:0042645", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0042645", "evidence": [ { "database": "UniProtKB", "id": "A0AAA9TSS4", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TSS4" } ], "pmid": "" }, { "name": "ribonucleoprotein granule", "id": "GO:0035770", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0035770", "evidence": [ { "database": "UniProtKB", "id": "A0AAA9TSS4", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TSS4" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 1, "go_terms": [ { "name": "mitochondrial large ribosomal subunit assembly", "id": "GO:1902775", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:1902775", "evidence": [ { "database": "UniProtKB", "id": "A0AAA9TSS4", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TSS4" } ], 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"strand": "-", "evidence": [ { "database": "Ensembl Gene", "id": "ENSBTAG00000066502", "url": "https://www.ensembl.org/id/ENSBTAG00000066502" } ] } } ], "crossref": [ { "id": "A0AAA9TSV4", "url": "https://alphafold.ebi.ac.uk/entry/A0AAA9TSV4", "database": "AlphaFoldDB", "categories": [] }, { "id": "cd15420", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd15420", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "514891", "url": "https://www.ncbi.nlm.nih.gov/gene/514891", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR000276", "url": "https://www.ebi.ac.uk/interpro/entry/IPR000276", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR000725", "url": "https://www.ebi.ac.uk/interpro/entry/IPR000725", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR017452", "url": "https://www.ebi.ac.uk/interpro/entry/IPR017452", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "bta:514891", "url": "https://www.genome.jp/dbget-bin/www_bget?bta:514891", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "PTHR26453", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR26453", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF13853", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF13853", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "NP_001376887", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001376887", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0AAA9TSV4", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TSV4", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0AAA9TSV4-1", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TSV4-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MEGNQSWIAEFILLGFQLSEDMELLLFVIFILLYTFNLLANGMILGLISLEPRLHTPMYYFLSHLAITDVAYASSHLPNMLENLVKHKKTISYFSCTMQMVSYLAFASVECLTLVVMSYDRFVAICHPLQYTVIMNWRVCTFLAIACWACGFSLAIVQVSLFLRLPFCGPQKVNHFFCEIRSVLKVTCGETWINDIFLLADGVFILIAPISLVLVSYVRILWAILKIQSKEGRKKAFSTCSSHLCVVGFYFGIVLMVYMIPDDNNREEPQKILFLFYTFFNPLLNPLVYSLRNAQVKAAFHRLLQKRRTV", "length": 310, "header": "tr|A0AAA9TSV4-1|A0AAA9TSV4_BOVIN Isoform 1 of Olfactory receptor OS=Bos taurus OX=9913 GN=OR2A70 PE=3 SV=1 CANONICAL=A0AAA9TSV4-1" }, "isoforms": [ { "isoform_ac": "A0AAA9TSV4-1", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TSV4/entry", "sequence": { "sequence": "MEGNQSWIAEFILLGFQLSEDMELLLFVIFILLYTFNLLANGMILGLISLEPRLHTPMYYFLSHLAITDVAYASSHLPNMLENLVKHKKTISYFSCTMQMVSYLAFASVECLTLVVMSYDRFVAICHPLQYTVIMNWRVCTFLAIACWACGFSLAIVQVSLFLRLPFCGPQKVNHFFCEIRSVLKVTCGETWINDIFLLADGVFILIAPISLVLVSYVRILWAILKIQSKEGRKKAFSTCSSHLCVVGFYFGIVLMVYMIPDDNNREEPQKILFLFYTFFNPLLNPLVYSLRNAQVKAAFHRLLQKRRTV", "length": 310, "header": "tr|A0AAA9TSV4-1|A0AAA9TSV4_BOVIN Isoform 1 of Olfactory receptor OS=Bos taurus OX=9913 GN=OR2A70 PE=3 SV=1 CANONICAL=A0AAA9TSV4-1" }, "locus": { "chromosome": "4", "start_pos": 107372923, "end_pos": 107371994, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000131108.1", "url": "https://www.ensembl.org/id/ENSBTAT00000131108.1" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000100426.1", "url": "https://www.ensembl.org/id/ENSBTAP00000100426.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [ { "id": "bta:514891", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?bta:514891", "resource": "KEGG Pathway" } ], "orthologs": [], "go_annotation": { "categories": [ { "name": "Molecular Function", "total": 2, "go_terms": [ { "name": "G protein-coupled receptor activity", "id": "GO:0004930", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0004930", "evidence": [ { "database": "UniProtKB", "id": "A0AAA9TSV4", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TSV4" } ], "pmid": "" }, { "name": "olfactory receptor activity", "id": "GO:0004984", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0004984", "evidence": [ { "database": "UniProtKB", "id": "A0AAA9TSV4", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TSV4" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 1, "go_terms": [ { "name": "plasma membrane", "id": "GO:0005886", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005886", "evidence": [ { "database": "UniProtKB", "id": "A0AAA9TSV4", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TSV4" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 4, "end_pos": 6, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A0AAA9TSV4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TSV4" }, { "id": "PS50262", "database": "PROSITE", "url": "https://prosite.expasy.org/PS50262" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "G-protein coupled receptors family 1 profile", "eco_id": "ECO_0000259", "start_pos": 40, "end_pos": 289, "start_aa": "Ala", "end_aa": "Tyr", "glycosite_overlap": [] } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 4, "end_pos": 6 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ], "tool_support": { "graph_view": "yes" } }, { "uniprot_canonical_ac": "A0AAA9TSV8-1", "uniprot_ac": "A0AAA9TSV8", "uniprot_id": "A0AAA9TSV8_BOVIN", "mass": { "chemical_mass": 88803.0, "monoisotopic_mass": 88803.0 }, "refseq": {}, "gene_names": [ { "name": "CDH26", "type": "recommended", "evidence": [ { "id": "A0AAA9TSV8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TSV8" } ] } ], "protein_names": [ { "name": "Cadherin-like protein 26", "type": "recommended", "evidence": [ { "id": "A0AAA9TSV8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TSV8/entry#names_and_taxonomy" } ] } ], "function": [ { "annotation": "Cadherins are calcium-dependent cell adhesion proteins. They preferentially interact with themselves in a homophilic manner in connecting cells; cadherins may thus contribute to the sorting of heterogeneous cell types. Ligand for integrins alpha-E/beta-7, ITGAE:ITGAB7, alpha-4/beta-7, ITGA4:ITGAB7 and alpha-4/beta-1, ITGA4:ITGAB1 through which modulates CD4(+) T cells activation.", "evidence": [ { "database": "UniProtKB", "id": "A0AAA9TSV8", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TSV8#function" }, { "database": "UniProtKB", "id": "ARBA00059993", "url": "https://www.uniprot.org/uniprotkb/ARBA00059993#function" }, { "database": "UniProtKB", "id": "F1MKX3", "url": "https://www.uniprot.org/uniprotkb/F1MKX3#function" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Bos taurus", "taxid": 9913, "evidence": [ { "database": "UniProtKB", "id": "A0AAA9TSV8", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TSV8" } ], "common_name": "Bovine", "glygen_name": "Bovine", "reference_species": "Bos taurus [9913]" } ], "gene": [ { "name": "CDH26", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TSV8", "locus": { "chromosome": "13", "start_pos": 56543952, "end_pos": 56591024, "strand": "+", "evidence": [ { "database": "Ensembl Gene", "id": "ENSBTAG00000020261", "url": "https://www.ensembl.org/id/ENSBTAG00000020261" } ] } } ], "crossref": [ { "id": "A0AAA9TSV8", "url": "https://alphafold.ebi.ac.uk/entry/A0AAA9TSV8", "database": "AlphaFoldDB", "categories": [] }, { "id": "ENSBTAG00000020261", "url": "https://bgee.org/?page=gene&gene_id=ENSBTAG00000020261", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "cd11304", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd11304", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "IPR002126", "url": "https://www.ebi.ac.uk/interpro/entry/IPR002126", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR015919", "url": "https://www.ebi.ac.uk/interpro/entry/IPR015919", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR020894", "url": "https://www.ebi.ac.uk/interpro/entry/IPR020894", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR027397", "url": "https://www.ebi.ac.uk/interpro/entry/IPR027397", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR039808", "url": "https://www.ebi.ac.uk/interpro/entry/IPR039808", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "F1MKX3", "url": "https://www.orthodb.org/?gene=F1MKX3", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR24027", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR24027", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR24027:SF78", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR24027:SF78", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00028", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00028", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "A0AAA9TSV8", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TSV8", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0AAA9TSV8-1", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TSV8-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "F1MKX3", "url": "https://www.uniprot.org/uniprotkb/F1MKX3", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "F1MKX3-1", "url": "https://www.uniprot.org/uniprotkb/F1MKX3-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MCSRVHPELLLLLSLLMLVSTVNSTRQENDDLTNQTKGDSRLLRRSKRRWVITTLELEEEDPGPFPKFVGELFNNMSANMEIIYLIRGPGVDEYPEIGLFSIEDNVNGKIYVHRPVDREKTPSFKVYFDVANRLTGHIVDKSLIVNIRIKDVNDHAPEFPEKEFNISVKEDHAAGIQGQPVFQMSAVDLDQENTPNSQVLYFLVSQTPVLRESGFRIDRVSGEVRLSGCLDYEMAPRFTLLIEARDCGNPPLSSTATVHVHVQDSNNHMPRFTQDHYNVQISEGWASQGVLRLGVQDGDSPSTAAWRVKFNITNGNEEGHFHISTDPETNEGILNIIKPLDHETQAEWNLVVAVENEEPLFSCDAGQLQRPRQASASATVSVWVTNVNDPPTFHPGTFIVSEVDGAGPGTQLGMFNATDPDRTAAGQIRYKLAYDPANWVSIDERSGVVITVKPVDRESPHVNDSIYVIIAHAVDDGVPPQTGTGTMLLFLSDVNDNAPTLRLSSQHLEVCQSAGDKSLLIEAEDSDLEPYSDPFTFKLDSTWGDTEDMWRLGENRGCSVELLMQRSLPLGDYSVPLLIGDKQGLSQKQTVHVRVCSCPDGFTCAEPLIARAGVMKGALAPLCVAFMALAAALLLLLRCRLVSEANRQGPSVPQDEGIQTLLAWNEESRADPLQGRSYLGDHMPALSISAAQAGAKLGAKGHGVFFEPSVRNKYSTPVCLNTVVPRGPLEMRAGVMAKVLSQLCGTRDPEGDPGYPPHVYAEEGECEQADSLSSLTFSEHDLPPDVLDSLGPKAAPLEEIYSQSAFRS", "length": 808, "header": "tr|A0AAA9TSV8-1|A0AAA9TSV8_BOVIN Isoform 1 of Cadherin-like protein 26 OS=Bos taurus OX=9913 GN=CDH26 PE=4 SV=1 CANONICAL=A0AAA9TSV8-1" }, "isoforms": [ { "isoform_ac": "A0AAA9TSV8-1", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TSV8/entry", "sequence": { "sequence": "MCSRVHPELLLLLSLLMLVSTVNSTRQENDDLTNQTKGDSRLLRRSKRRWVITTLELEEEDPGPFPKFVGELFNNMSANMEIIYLIRGPGVDEYPEIGLFSIEDNVNGKIYVHRPVDREKTPSFKVYFDVANRLTGHIVDKSLIVNIRIKDVNDHAPEFPEKEFNISVKEDHAAGIQGQPVFQMSAVDLDQENTPNSQVLYFLVSQTPVLRESGFRIDRVSGEVRLSGCLDYEMAPRFTLLIEARDCGNPPLSSTATVHVHVQDSNNHMPRFTQDHYNVQISEGWASQGVLRLGVQDGDSPSTAAWRVKFNITNGNEEGHFHISTDPETNEGILNIIKPLDHETQAEWNLVVAVENEEPLFSCDAGQLQRPRQASASATVSVWVTNVNDPPTFHPGTFIVSEVDGAGPGTQLGMFNATDPDRTAAGQIRYKLAYDPANWVSIDERSGVVITVKPVDRESPHVNDSIYVIIAHAVDDGVPPQTGTGTMLLFLSDVNDNAPTLRLSSQHLEVCQSAGDKSLLIEAEDSDLEPYSDPFTFKLDSTWGDTEDMWRLGENRGCSVELLMQRSLPLGDYSVPLLIGDKQGLSQKQTVHVRVCSCPDGFTCAEPLIARAGVMKGALAPLCVAFMALAAALLLLLRCRLVSEANRQGPSVPQDEGIQTLLAWNEESRADPLQGRSYLGDHMPALSISAAQAGAKLGAKGHGVFFEPSVRNKYSTPVCLNTVVPRGPLEMRAGVMAKVLSQLCGTRDPEGDPGYPPHVYAEEGECEQADSLSSLTFSEHDLPPDVLDSLGPKAAPLEEIYSQSAFRS", "length": 808, "header": "tr|A0AAA9TSV8-1|A0AAA9TSV8_BOVIN Isoform 1 of Cadherin-like protein 26 OS=Bos taurus OX=9913 GN=CDH26 PE=4 SV=1 CANONICAL=A0AAA9TSV8-1" }, "locus": { "chromosome": "13", "start_pos": 56590691, "end_pos": 56544956, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000078709.2", "url": "https://www.ensembl.org/id/ENSBTAT00000078709.2" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000100144.1", "url": "https://www.ensembl.org/id/ENSBTAP00000100144.1" } ] } }, { "isoform_ac": "F1MKX3-1", "url": "https://www.uniprot.org/uniprotkb/F1MKX3/entry", "sequence": { "sequence": "MCSRVHPELLLLLSLLMLVSTVNSTRQENDDLTNQTKGDSRLLRRSKRRWVITTLELEEEDPGPFPKFVGELFNNMSANMEIIYLIRGPGVDEYPEIGLFSIEDNVNGKIYVHRPVDREKTPSFKVYFDVANRLTGHIVDKSLIVNIRIKDVNDHAPEFPEKEFNISVKEDHAAGQPVFQMSAVDLDQENTPNSQVLYFLVSQTPVLRESGFRIDRVSGEVRLSGCLDYEMAPRFTLLIEARDCGNPPLSSTATVHVHVQDSNNHMPRFTQDHYNVQISEGWASQGVLRLGVQDGDSPSTAAWRVKFNITNGNEEGHFHISTDPETNEGILNIIKPLDHETQAEWNLVVAVENEEPLFSCDAGQLQRPRQASASATVSVWVTNVNDPPTFHPGTFIVSEVDGAGPGTQLGMFNATDPDRTAAGQIRYKLAYDPANWVSIDERSGVVITVKPVDRESPHVNDSIYVIIAHAVDDGVPPQTGTGTMLLFLSDVNDNAPTLRLSSQHLEVCQSAGDKSLLIEAEDSDLEPYSDPFTFKLDSTWGDTEDMWRLGENRGCSVELLMQRSLPLGDYSVPLLIGDKQGLSQKQTVHVRVCSCPDGFTCAEPLIARAGVMKGALAPLCVAFMALAAALLLLLRCRLVSEANRQGPSVPQDEGIQTLLAWNEESRADPLQGRSYLGDHMPALSISAAQAGAKLGAKGHGVFFEPSVRNKYSTPLAVVLAWSAALRSGIIWSLLRCPPPAGLPQYRGAQRTPGNESRSDGKGAESAALWHP", "length": 771, "header": "tr|F1MKX3-1|F1MKX3_BOVIN Computationally mapped isoform of Cadherin-like protein 26 OS=Bos taurus OX=9913 GN=CDH26 PE=4 SV=4 CANONICAL=A0AAA9TSV8-1" }, "locus": { "chromosome": "13", "start_pos": 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"UniProtKB", "id": "A0AAA9TSX4", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TSX4" } ], "common_name": "Bovine", "glygen_name": "Bovine", "reference_species": "Bos taurus [9913]" } ], "gene": [ { "name": "RUNX3", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TSX4", "locus": { "chromosome": "2", "start_pos": 128062834, "end_pos": 127998390, "strand": "-", "evidence": [ { "database": "Ensembl Gene", "id": "ENSBTAG00000050474", "url": "https://www.ensembl.org/id/ENSBTAG00000050474" } ] } } ], "crossref": [ { "id": "A0AAA9TSX4", "url": "https://alphafold.ebi.ac.uk/entry/A0AAA9TSX4", "database": "AlphaFoldDB", "categories": [] }, { "id": "ENSBTAG00000050474", "url": "https://bgee.org/?page=gene&gene_id=ENSBTAG00000050474", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "617389", "url": "https://www.ncbi.nlm.nih.gov/gene/617389", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR000040", "url": "https://www.ebi.ac.uk/interpro/entry/IPR000040", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR008967", "url": "https://www.ebi.ac.uk/interpro/entry/IPR008967", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR012346", "url": "https://www.ebi.ac.uk/interpro/entry/IPR012346", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR013524", "url": "https://www.ebi.ac.uk/interpro/entry/IPR013524", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR013711", "url": "https://www.ebi.ac.uk/interpro/entry/IPR013711", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR016554", "url": "https://www.ebi.ac.uk/interpro/entry/IPR016554", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "TQGLWPE", "url": "https://omabrowser.org/oma/group/TQGLWPE/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "A0A3Q1MYL2", "url": "https://www.orthodb.org/?gene=A0A3Q1MYL2", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR11950", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR11950", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR11950:SF43", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR11950:SF43", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00853", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00853", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF08504", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF08504", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "R-BTA-8941855", "url": "https://www.reactome.org/PathwayBrowser/#R-BTA-8941855", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "R-BTA-8941856", "url": "https://www.reactome.org/PathwayBrowser/#R-BTA-8941856", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "R-BTA-8941858", "url": "https://www.reactome.org/PathwayBrowser/#R-BTA-8941858", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "R-BTA-8951430", "url": "https://www.reactome.org/PathwayBrowser/#R-BTA-8951430", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "R-BTA-8951671", "url": "https://www.reactome.org/PathwayBrowser/#R-BTA-8951671", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "R-BTA-8951936", "url": "https://www.reactome.org/PathwayBrowser/#R-BTA-8951936", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "NP_001356796", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001356796", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A3Q1MYL2", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1MYL2", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A3Q1MYL2-1", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1MYL2-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0AAA9TSX4", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TSX4", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0AAA9TSX4-1", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TSX4-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0AAA9TUJ4", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TUJ4", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0AAA9TUJ4-1", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TUJ4-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MASNSIFDSFSTYSQTFIRDPSTSRRFTPPSTAFPCGGGGGGGGGKMGENSGALTAQAAVGPGGRARPEVRSMVDVLADHAGELVRTDSPNFLCSVLPSHWRCNKTLPVAFKVVALGDVPDGTVVTVMAGNDENYSAELRNASAVMKNQVARFNDLRFVGRSGRGKSFTLTITVFTNPTQVATYHRAIKVTVDGPREPRRHRQKLEDQTKGFPDRFGDLERLRMRVTPSTPSPRSSLSTTSHFGSQAQTPIQGTSELNPFSDPRQFDRSFLPPLTESRFSDPRMHYPGAMSAAFPYSATPSGTSISSLSVASMPAGGRFHHTYLPPPYPGAPQNQSGPFPASPSPYHLYYGASSGSYQFSMTAGGGGGGSGGDRSPTRMLASCTSSAAAVATGSLMNPSLGGQSDGVEADGSHSNSPTALSTPGRMDEAVWRPY", "length": 434, "header": "tr|A0AAA9TSX4-1|A0AAA9TSX4_BOVIN Isoform 1 of Runt-related transcription factor OS=Bos taurus OX=9913 GN=RUNX3 PE=4 SV=1 CANONICAL=A0AAA9TSX4-1" }, "isoforms": [ { "isoform_ac": "A0A3Q1MYL2-1", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1MYL2/entry", "sequence": { "sequence": "MLRDPSTSRRFTPPSTAFPCGGGGGGGGGKMGENSGALTAQAAVGPGGRARPEVRSMVDVLADHAGELVRTDSPNFLCSVLPSHWRCNKTLPVAFKVVALGDVPDGTVVTVMAGNDENYSAELRNASAVMKNQVARFNDLRFVGRSGRGKSFTLTITVFTNPTQVATYHRAIKVTVDGPREPRRHRQKLEDQTKGFPDRFGDLERLRMRVTPSTPSPRSSLSTTSHFGSQAQTPIQGTSELNPFSDPRQFDRSFLPPLTESRFSDPRMHYPGAMSAAFPYSATPSGTSISSLSVASMPAGGRFHHTYLPPPYPGAPQNQSGPFPASPSPYHLYYGASSGSYQFSMTAGGGGGGSGGDRSPTRMLASCTSSAAAVATGSLMNPSLGGQSDGVEADGSHSNSPTALSTPGRMDEAVWRPY", "length": 418, "header": "tr|A0A3Q1MYL2-1|A0A3Q1MYL2_BOVIN Computationally mapped isoform of Runt-related transcription factor OS=Bos taurus OX=9913 GN=RUNX3 PE=4 SV=2 CANONICAL=A0AAA9TSX4-1" }, "locus": { "chromosome": "2", "start_pos": 128060616, "end_pos": 128028906, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000070567.2", "url": "https://www.ensembl.org/id/ENSBTAT00000070567.2" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000061160.2", "url": "https://www.ensembl.org/id/ENSBTAP00000061160.2" } ] } }, { "isoform_ac": "A0AAA9TSX4-1", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TSX4/entry", "sequence": { "sequence": "MASNSIFDSFSTYSQTFIRDPSTSRRFTPPSTAFPCGGGGGGGGGKMGENSGALTAQAAVGPGGRARPEVRSMVDVLADHAGELVRTDSPNFLCSVLPSHWRCNKTLPVAFKVVALGDVPDGTVVTVMAGNDENYSAELRNASAVMKNQVARFNDLRFVGRSGRGKSFTLTITVFTNPTQVATYHRAIKVTVDGPREPRRHRQKLEDQTKGFPDRFGDLERLRMRVTPSTPSPRSSLSTTSHFGSQAQTPIQGTSELNPFSDPRQFDRSFLPPLTESRFSDPRMHYPGAMSAAFPYSATPSGTSISSLSVASMPAGGRFHHTYLPPPYPGAPQNQSGPFPASPSPYHLYYGASSGSYQFSMTAGGGGGGSGGDRSPTRMLASCTSSAAAVATGSLMNPSLGGQSDGVEADGSHSNSPTALSTPGRMDEAVWRPY", "length": 434, "header": "tr|A0AAA9TSX4-1|A0AAA9TSX4_BOVIN Isoform 1 of Runt-related transcription factor OS=Bos taurus OX=9913 GN=RUNX3 PE=4 SV=1 CANONICAL=A0AAA9TSX4-1" }, "locus": { "chromosome": "2", "start_pos": 128060616, "end_pos": 127998918, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000112776.1", "url": "https://www.ensembl.org/id/ENSBTAT00000112776.1" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000101478.1", "url": "https://www.ensembl.org/id/ENSBTAP00000101478.1" } ] } }, { "isoform_ac": "A0AAA9TUJ4-1", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TUJ4/entry", "sequence": { "sequence": "MVLLAPTPMRARRGHSSPWPRAARKVAHGSVLQRPLADPSTSRRFTPPSTAFPCGGGGGGGGGKMGENSGALTAQAAVGPGGRARPEVRSMVDVLADHAGELVRTDSPNFLCSVLPSHWRCNKTLPVAFKVVALGDVPDGTVVTVMAGNDENYSAELRNASAVMKNQVARFNDLRFVGRSGRGKSFTLTITVFTNPTQVATYHRAIKVTVDGPREPRRHRQKLEDQTKGFPDRFGDLERLRMRVTPSTPSPRSSLSTTSHFGSQAQTPIQGTSELNPFSDPRQFDRSFLPPLTESRFSDPRMHYPGAMSAAFPYSATPSGTSISSLSVASMPAGGRFHHTYLPPPYPGAPQNQSGPFPASPSPYHLYYGASSGSYQFSMTAGGGGGGSGGDRSPTRMLASCTSSAAAVATGSLMNPSLGGQSDGVEADGSHSNSPTALSTPGRMDEAVWRPY", "length": 452, "header": "tr|A0AAA9TUJ4-1|A0AAA9TUJ4_BOVIN Computationally mapped isoform of Runt-related transcription factor OS=Bos taurus OX=9913 GN=RUNX3 PE=4 SV=1 CANONICAL=A0AAA9TSX4-1" }, "locus": { "chromosome": "2", "start_pos": 128060616, "end_pos": 128030624, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000113622.1", "url": "https://www.ensembl.org/id/ENSBTAT00000113622.1" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000100784.1", "url": "https://www.ensembl.org/id/ENSBTAP00000100784.1" } ] } } ], "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "other", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 227, "start_aa": "Thr", "end_pos": 227, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr227", "evidence": [ { "id": "", "database": "GlyGen", "url": "https://data.glygen.org/" } ], "filter_code": "000000000000000010000.00000000001000.0.01000" }, { "glytoucan_ac": "", "type": "O-linked", "subtype": "other", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 230, "start_aa": "Thr", "end_pos": 230, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr230", "evidence": [ { "id": "", "database": "GlyGen", "url": "https://data.glygen.org/" } ], "filter_code": "000000000000000010000.00000000001000.0.01000" }, { "glytoucan_ac": "", "type": "O-linked", "subtype": "other", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 299, "start_aa": "Thr", "end_pos": 299, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr299", "evidence": [ { "id": "", "database": "GlyGen", "url": "https://data.glygen.org/" } ], "filter_code": "000000000000000010000.00000000001000.0.01000" } ], "phosphorylation": [], "glycation": [], "keywords": [ "glycoprotein", "glycoprotein_predicted" ], "publication": [], "pathway": [ { "id": "R-BTA-8941855", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-BTA-8941855", "resource": "Reactome", "description": "RUNX3 regulates CDKN1A transcription" }, { "id": "R-BTA-8941856", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-BTA-8941856", "resource": "Reactome", "description": "RUNX3 regulates NOTCH signaling" }, { "id": "R-BTA-8941858", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-BTA-8941858", "resource": "Reactome", "description": "Regulation of RUNX3 expression and activity" }, { "id": "R-BTA-8951430", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-BTA-8951430", "resource": "Reactome", "description": "RUNX3 regulates WNT signaling" }, { "id": "R-BTA-8951671", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-BTA-8951671", "resource": "Reactome", "description": "RUNX3 regulates YAP1-mediated transcription" }, { "id": "R-BTA-8951936", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-BTA-8951936", "resource": "Reactome", "description": "RUNX3 regulates p14-ARF" } ], "orthologs": [ { "uniprot_canonical_ac": "A0A0G2K7T0-1", "protein_name": "Runt-related transcription factor", "gene_name": "Runx3", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MASNSIFDSFPNYTPTFIRDPSTSRRFTPPSTAFPCGGGGGGKMGENSGALSAQAAAGPGGRTRPEVRSMVDVLADHAGELVRTDSPNFLCSVLPSHWRCNKTLPVAFKVVALGDVPDGTVVTVMAGNDENYSAELRNASAVMKNQVARFNDLRFVGRSGRGKSFTLTITVFTNPTQVATYHRAIKVTVDGPREPRRHRQKIEDQTKAFPDRFGDLRMRVTPSTPSPRGSLSTTSHFSSQAQTPIQGSSDLNPFSDPRQFDRSFPTLQSLTESRFPDPRMHYPGAMSAAFPYSATPSGTSLGGLSVAGMPASSRFHHTYLPPPYPGAPQSQSGPFQANPAPYHLFYGTSSGSYQFSMAAAGGGERSPTRMLTSCPTGASVSAGNLMNPSLGQADGVEADGSHSNSPTALSTPGRMDEAVWRPY", "length": 423 }, "evidence": [ { "id": "A0AAA9TSX4", "url": "https://omabrowser.org/oma/group/A0AAA9TSX4/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "A0A1D5P8K0-1", "protein_name": "Runt-related transcription factor", "gene_name": "RUNX3", "tax_id": 9031, "organism": "Gallus gallus", "sequence": { "sequence": "MASNGVFDSFAAYSSTFLRDPSTSRRFTPPSTAFPCGKMGENSGALGAAAAGGRARPEVRSVVDVLADHAGELVRTDSPNFLCSVLPSHWRCNKTLPVAFKVVALGDVPDGTVVTVMAGNDENYSAELRNASAVMKNQVARFNDLRFVGRSGRGKSFTLTITVFTNPTQVATYHRAIKVTVDGPREPRRHRQKLEDQTKPFADRYGELERLRQSMRVTPTTPSPRGSISTPSHFGSQAQTPIQGTSELSPFSDPRQFDRSFPTLPTLTETRFSDPRMHYPGAMTATFPYTATPSATGIGGISMTSMPTTARFHHTYLPPPYPGSTQNQSGPFQTNPSPYHLYYGTSSGSYQFSMVAGGERSPTRMLSSCTSASAGNNLMNPNLGNQNDGVDADGSHSNSPTTMTTTGRMDESVWRPY", "length": 417 }, "evidence": [ { "id": "A0AAA9TSX4", "url": "https://omabrowser.org/oma/group/A0AAA9TSX4/", "database": "OMA" } ], "glygen_name": "Chicken", "common_name": "Chicken" }, { "uniprot_canonical_ac": "Q13761-1", "protein_name": "Runt-related transcription factor 3", "gene_name": "RUNX3", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MRIPVDPSTSRRFTPPSPAFPCGGGGGKMGENSGALSAQAAVGPGGRARPEVRSMVDVLADHAGELVRTDSPNFLCSVLPSHWRCNKTLPVAFKVVALGDVPDGTVVTVMAGNDENYSAELRNASAVMKNQVARFNDLRFVGRSGRGKSFTLTITVFTNPTQVATYHRAIKVTVDGPREPRRHRQKLEDQTKPFPDRFGDLERLRMRVTPSTPSPRGSLSTTSHFSSQPQTPIQGTSELNPFSDPRQFDRSFPTLPTLTESRFPDPRMHYPGAMSAAFPYSATPSGTSISSLSVAGMPATSRFHHTYLPPPYPGAPQNQSGPFQANPSPYHLYYGTSSGSYQFSMVAGSSSGGDRSPTRMLASCTSSAASVAAGNLMNPSLGGQSDGVEADGSHSNSPTALSTPGRMDEAVWRPY", "length": 415 }, "evidence": [ { "id": "A0AAA9TSX4", "url": "https://omabrowser.org/oma/group/A0AAA9TSX4/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" } ], "go_annotation": { "categories": [ { "name": "Molecular Function", "total": 6, "go_terms": [ { "name": "DNA-binding transcription factor activity", "id": "GO:0003700", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003700", "evidence": [ { "database": "UniProtKB", "id": "A0AAA9TSX4", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TSX4" } ], "pmid": "" }, { "name": "ATP binding", "id": "GO:0005524", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005524", "evidence": [ { "database": "UniProtKB", "id": "A0AAA9TSX4", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TSX4" } ], "pmid": "" }, { "name": "sequence-specific double-stranded DNA binding", "id": "GO:1990837", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:1990837", "evidence": [ { "database": "UniProtKB", "id": "A0AAA9TSX4", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TSX4" } ], "pmid": "" }, { "name": "transcription corepressor binding", "id": "GO:0001222", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0001222", "evidence": [ { "database": "UniProtKB", "id": "A0AAA9TSX4", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TSX4" } ], "pmid": "" }, { "name": "RNA polymerase II cis-regulatory region sequence-specific DNA binding", "id": "GO:0000978", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000978", "evidence": [ { "database": "UniProtKB", "id": "A0AAA9TSX4", "url": 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"https://omabrowser.org/oma/group/A0AAA9TT41/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "P62332-1", "protein_name": "ADP-ribosylation factor 6", "gene_name": "Arf6", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MGKVLSKIFGNKEMRILMLGLDAAGKTTILYKLKLGQSVTTIPTVGFNVETVTYKNVKFNVWDVGGQDKIRPLWRHYYTGTQGLIFVVDCADRDRIDEARQELHRIINDREMRDAIILIFANKQDLPDAMKPHEIQEKLGLTRIRDRNWYVQPSCATSGDGLYEGLTWLTSNYKS", "length": 175 }, "evidence": [ { "id": "A0AAA9TT41", "url": "https://omabrowser.org/oma/group/A0AAA9TT41/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "Q007T5-1", "protein_name": "ADP-ribosylation factor 6", "gene_name": "ARF6", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MGKVLSKIFGNKEMRILMLGLDAAGKTTILYKLKLGQSVTTIPTVGFNVETVTYKNVKFNVWDVGGQDKIRPLWRHYYTGTQGLIFVVDCADRDRIDEARQELHRIINDREMRDAIILIFANKQDLPDAMKPHEIQEKLGLTRIRDRNWYVQPSCATSGDGLYEGLTWLTSNYKS", "length": 175 }, "evidence": [ { "id": "A0AAA9TT41", "url": "https://omabrowser.org/oma/group/A0AAA9TT41/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" } ], "go_annotation": { "categories": [ { "name": "Biological Process", "total": 19, "go_terms": [ { "name": "positive regulation of mitotic cytokinetic process", "id": "GO:1903438", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:1903438", "evidence": [ { "database": "UniProtKB", "id": "A0AAA9TT41", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TT41" } ], "pmid": "" }, { "name": "positive regulation of neuron projection development", "id": "GO:0010976", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0010976", "evidence": [ { "database": "UniProtKB", "id": "A0AAA9TT41", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TT41" } ], "pmid": "" 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"https://www.uniprot.org/uniprotkb/A0AAA9TT41" } ], "pmid": "" }, { "name": "positive regulation of protein localization to plasma membrane", "id": "GO:1903078", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:1903078", "evidence": [ { "database": "UniProtKB", "id": "A0AAA9TT41", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TT41" } ], "pmid": "" }, { "name": "protein localization to endosome", "id": "GO:0036010", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0036010", "evidence": [ { "database": "UniProtKB", "id": "A0AAA9TT41", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TT41" } ], "pmid": "" }, { "name": "cortical actin cytoskeleton organization", "id": "GO:0030866", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030866", "evidence": [ { "database": "UniProtKB", "id": "A0AAA9TT41", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TT41" } ], "pmid": "" }, { "name": "negative regulation of protein localization to cell surface", "id": "GO:2000009", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:2000009", "evidence": [ { "database": "UniProtKB", "id": "A0AAA9TT41", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TT41" } ], "pmid": "" }, { "name": "ruffle assembly", "id": "GO:0097178", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0097178", "evidence": [ { "database": "UniProtKB", "id": "A0AAA9TT41", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TT41" } ], "pmid": "" }, { "name": "positive regulation of actin filament polymerization", "id": "GO:0030838", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030838", "evidence": [ { "database": "UniProtKB", "id": "A0AAA9TT41", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TT41" } ], "pmid": "" }, { "name": "protein localization to cell surface", "id": "GO:0034394", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0034394", "evidence": [ { "database": "UniProtKB", "id": "A0AAA9TT41", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TT41" } ], "pmid": "" }, { "name": "regulation of Rac protein signal transduction", "id": "GO:0035020", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0035020", "evidence": [ { "database": "UniProtKB", "id": "A0AAA9TT41", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TT41" } ], "pmid": "" }, { "name": "regulation of filopodium assembly", "id": "GO:0051489", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0051489", "evidence": [ { "database": "UniProtKB", "id": "A0AAA9TT41", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TT41" } ], "pmid": "" }, { "name": "regulation of dendritic spine development", "id": "GO:0060998", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0060998", "evidence": [ { "database": "UniProtKB", "id": "A0AAA9TT41", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TT41" } ], "pmid": "" }, { "name": "endocytic recycling", "id": "GO:0032456", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0032456", "evidence": [ { "database": "UniProtKB", "id": "A0AAA9TT41", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TT41" } ], "pmid": "" }, { "name": "positive regulation of focal adhesion disassembly", "id": "GO:0120183", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0120183", "evidence": [ { "database": "UniProtKB", "id": "A0AAA9TT41", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TT41" } ], "pmid": "" }, { "name": "protein localization to cleavage furrow", "id": "GO:1905345", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:1905345", "evidence": [ { "database": "UniProtKB", "id": "A0AAA9TT41", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TT41" } ], "pmid": "" } ] }, { "name": "Molecular Function", "total": 6, "go_terms": [ { "name": "GTP binding", "id": "GO:0005525", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005525", "evidence": [ { "database": "UniProtKB", "id": "A0AAA9TT41", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TT41" } ], "pmid": "" }, { "name": "metal ion binding", "id": "GO:0046872", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0046872", "evidence": [ { "database": "UniProtKB", "id": "A0AAA9TT41", 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"PF00651", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00651", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF01344", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF01344", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF07707", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF07707", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "R-BTA-8951664", "url": "https://www.reactome.org/PathwayBrowser/#R-BTA-8951664", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "R-BTA-983168", "url": "https://www.reactome.org/PathwayBrowser/#R-BTA-983168", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "A0AAA9TU80", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TU80", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0AAA9TU80-1", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TU80-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "F1N465", "url": "https://www.uniprot.org/uniprotkb/F1N465", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "F1N465-1", "url": "https://www.uniprot.org/uniprotkb/F1N465-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MAASADLSKSSPTPNGIPSSDTASDAMDPFHACSILKQLKTMYDEGQLTDIVVEVDHGKTFSCHRNVLAAISPYFRSMFTSGLTESTQKEVRIVGVEAESMDLVLNYAYTSRVVLTEANVQALFTAASIFQIPSIQDQCAKYMISHLDPQNSIGVFIFADHYGHQELGDRSKEYIRKKFLCVTKEQEFLQLTKDQLISILDSDDLNVDREEHVYESIVRWFEHEQNEREVHLPEIFAKCIRFPLMEDTFIEKIPPQFAQAIAKSCVEKGPASPNGCTQRLGMTASEMIICFDAAHKHSGKKQTVPCLDIFTGRVFKLCKPPNDLREVGILVSPDNDIYIAGGYRPSSSEVSIDHKAENDFWMYDHSTNRWLSKPSLLRARIGCKLVYCCGKMYAIGGRVYEGDGRNSLKSVECYDSRENRWTTVCAMPVAMEFHNAVEYKEKIYVLQGEFFLFYEPQKDYWGFLTPMTVPRIQGLAAVYKNSIYYIAGTCGNHQRMFTVEAYDIELNKWTRKKDFPCDESINPYLKLVLFQNKLHLFVRATQVTVEEHVFRTSRKNSLYQYDDITDQWMKVYETPDRLWDLGRHFECAVAKLKQTGTVCIKNSCTNCNVIL", "length": 611, "header": "tr|A0AAA9TU80-1|A0AAA9TU80_BOVIN Isoform 1 of Kelch repeat and BTB domain-containing protein 8 OS=Bos taurus OX=9913 GN=KBTBD8 PE=3 SV=1 CANONICAL=A0AAA9TU80-1" }, "isoforms": [ { "isoform_ac": "A0AAA9TU80-1", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TU80/entry", "sequence": { "sequence": "MAASADLSKSSPTPNGIPSSDTASDAMDPFHACSILKQLKTMYDEGQLTDIVVEVDHGKTFSCHRNVLAAISPYFRSMFTSGLTESTQKEVRIVGVEAESMDLVLNYAYTSRVVLTEANVQALFTAASIFQIPSIQDQCAKYMISHLDPQNSIGVFIFADHYGHQELGDRSKEYIRKKFLCVTKEQEFLQLTKDQLISILDSDDLNVDREEHVYESIVRWFEHEQNEREVHLPEIFAKCIRFPLMEDTFIEKIPPQFAQAIAKSCVEKGPASPNGCTQRLGMTASEMIICFDAAHKHSGKKQTVPCLDIFTGRVFKLCKPPNDLREVGILVSPDNDIYIAGGYRPSSSEVSIDHKAENDFWMYDHSTNRWLSKPSLLRARIGCKLVYCCGKMYAIGGRVYEGDGRNSLKSVECYDSRENRWTTVCAMPVAMEFHNAVEYKEKIYVLQGEFFLFYEPQKDYWGFLTPMTVPRIQGLAAVYKNSIYYIAGTCGNHQRMFTVEAYDIELNKWTRKKDFPCDESINPYLKLVLFQNKLHLFVRATQVTVEEHVFRTSRKNSLYQYDDITDQWMKVYETPDRLWDLGRHFECAVAKLKQTGTVCIKNSCTNCNVIL", "length": 611, "header": "tr|A0AAA9TU80-1|A0AAA9TU80_BOVIN Isoform 1 of Kelch repeat and BTB domain-containing protein 8 OS=Bos taurus OX=9913 GN=KBTBD8 PE=3 SV=1 CANONICAL=A0AAA9TU80-1" }, "locus": { "chromosome": "22", "start_pos": 34473997, "end_pos": 34462523, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000111682.1", "url": "https://www.ensembl.org/id/ENSBTAT00000111682.1" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000101927.1", "url": "https://www.ensembl.org/id/ENSBTAP00000101927.1" } ] } }, { "isoform_ac": "F1N465-1", "url": "https://www.uniprot.org/uniprotkb/F1N465/entry", "sequence": { "sequence": "MAASAGEFFLFYEPQKDYWGFLTPMTVPRIQGLAAVYKNSIYYIAGTCGNHQRMFTVEAYDIELNKWTRKKDFPCDESINPYLKLVLFQNKLHLFVRATQVTVEEHVFRTSRKNSLYQYDDITDQWMKVYETPDRLWDLGRHFECAVAKLYPQCLQKVL", "length": 159, "header": "tr|F1N465-1|F1N465_BOVIN Computationally mapped isoform of Kelch repeat and BTB domain containing 8 OS=Bos taurus OX=9913 GN=KBTBD8 PE=4 SV=3 CANONICAL=A0AAA9TU80-1" }, "locus": { "chromosome": "22", "start_pos": 34473997, "end_pos": 34464049, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000014711.7", "url": "https://www.ensembl.org/id/ENSBTAT00000014711.7" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000014711.6", "url": "https://www.ensembl.org/id/ENSBTAP00000014711.6" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [ { "id": "R-BTA-8951664", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-BTA-8951664", "resource": "Reactome", "description": "Neddylation" }, { "id": "R-BTA-983168", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-BTA-983168", "resource": "Reactome", "description": "Antigen processing: Ubiquitination & Proteasome degradation" } ], "orthologs": [], "go_annotation": { "categories": [ { "name": "Biological Process", "total": 5, "go_terms": [ { "name": "neural crest formation", "id": "GO:0014029", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0014029", "evidence": [ { "database": "UniProtKB", "id": "A0AAA9TU80", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TU80" } ], "pmid": "" }, { "name": "regulation of translation", "id": "GO:0006417", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006417", "evidence": [ { "database": "UniProtKB", "id": "A0AAA9TU80", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TU80" } ], "pmid": "" }, { "name": "neural crest cell development", "id": "GO:0014032", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0014032", "evidence": [ { "database": "UniProtKB", "id": "A0AAA9TU80", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TU80" } ], "pmid": "" }, { "name": "protein monoubiquitination", "id": "GO:0006513", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006513", "evidence": [ { "database": "UniProtKB", "id": "A0AAA9TU80", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TU80" } ], "pmid": "" }, { "name": "proteasome-mediated ubiquitin-dependent protein catabolic process", "id": "GO:0043161", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0043161", "evidence": [ { "database": "UniProtKB", "id": "A0AAA9TU80", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TU80" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 4, "go_terms": [ { "name": "Golgi apparatus", "id": "GO:0005794", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005794", "evidence": [ { "database": "UniProtKB", "id": "A0AAA9TU80", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TU80" } ], "pmid": "" }, { "name": "spindle", "id": "GO:0005819", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005819", "evidence": [ { "database": "UniProtKB", "id": "A0AAA9TU80", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TU80" } ], "pmid": "" }, { "name": "Cul3-RING ubiquitin ligase complex", "id": "GO:0031463", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0031463", "evidence": [ { "database": "UniProtKB", "id": "A0AAA9TU80", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TU80" } ], "pmid": "" }, { "name": "cytoplasm", "id": "GO:0005737", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005737", "evidence": [ { "database": "UniProtKB", "id": "A0AAA9TU80", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TU80" } ], "pmid": "" } ] }, { "name": "Molecular Function", "total": 1, "go_terms": [ { "name": "ubiquitin-like ligase-substrate adaptor activity", "id": "GO:1990756", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:1990756", "evidence": [ { "database": "UniProtKB", "id": "A0AAA9TU80", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TU80" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A0AAA9TU80", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TU80" }, { "id": "PS50097", "database": "PROSITE", "url": "https://prosite.expasy.org/PS50097" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "BTB", "eco_id": "ECO_0000259", "start_pos": 49, "end_pos": 117, "start_aa": "Thr", "end_aa": "Glu", "glycosite_overlap": [] } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ], "tool_support": { "graph_view": "yes" } }, { "uniprot_canonical_ac": "A0AAA9TUA7-1", "uniprot_ac": "A0AAA9TUA7", "uniprot_id": "A0AAA9TUA7_BOVIN", "mass": { "chemical_mass": 21833.0, "monoisotopic_mass": 21833.0 }, "refseq": { "ac": "XP_059747877", "name": "large ribosomal subunit protein uL6", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_059747877" }, "gene_names": [ { "name": "LOC107132967", "type": "recommended", "evidence": [ { "id": "A0AAA9TUA7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TUA7" } ] }, { "name": "LOC107132967", "type": "synonym", "evidence": [ { "id": "XP_059747877", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_059747877" } ] } ], "protein_names": [ { "name": "Large ribosomal subunit protein uL6", "type": "recommended", "evidence": [ { "id": "A0AAA9TUA7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TUA7/entry#names_and_taxonomy" } ] }, { "name": "60S ribosomal protein L9", "type": "synonym", "evidence": [ { "id": "A0AAA9TUA7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TUA7/entry#names_and_taxonomy" } ] }, { "name": "large ribosomal subunit protein uL6", "type": "synonym", "evidence": [ { "id": "XP_059747877", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_059747877" } ] } ], "function": [ { "annotation": "Component of the large ribosomal subunit. The ribosome is a large ribonucleoprotein complex responsible for the synthesis of proteins in the cell.", "evidence": [ { "database": "UniProtKB", "id": "A0AAA9TUA7", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TUA7#function" }, { "database": "UniProtKB", "id": "ARBA00034092", "url": "https://www.uniprot.org/uniprotkb/ARBA00034092#function" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Bos taurus", "taxid": 9913, "evidence": [ { "database": "UniProtKB", "id": "A0AAA9TUA7", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TUA7" } ], "common_name": "Bovine", "glygen_name": "Bovine", "reference_species": "Bos taurus [9913]" } ], "gene": [ { "name": "LOC107132967", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TUA7", "locus": {} } ], "crossref": [ { "id": "107132967", "url": "https://www.ncbi.nlm.nih.gov/gene/107132967", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR000702", "url": "https://www.ebi.ac.uk/interpro/entry/IPR000702", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR002359", "url": "https://www.ebi.ac.uk/interpro/entry/IPR002359", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR020040", "url": "https://www.ebi.ac.uk/interpro/entry/IPR020040", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR036789", "url": "https://www.ebi.ac.uk/interpro/entry/IPR036789", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "bta:107132967", "url": "https://www.genome.jp/dbget-bin/www_bget?bta:107132967", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "SARWACH", "url": "https://omabrowser.org/oma/group/SARWACH/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "PTHR11655", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR11655", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR11655:SF46", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR11655:SF46", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00347", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00347", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "XP_059747877", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_059747877", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0AAA9TUA7", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TUA7", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0AAA9TUA7-1", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TUA7-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MKTILSNQTVDIPENVDINLKGRTVIVKGPRGTLRRDFNHINVELSLLGKKKKRLRVDKWWGNRKELATVLTICSHVQNMIKGVTLGFRYKMRSVYAHFPINVVIQENGSLVEIRNFLGEKYIRRVRMRPGVACSVSQAQKDELILEGNDIELVSNSAALIQQATTVKNKDIRKFLDGIYVSEKGTVQQADE", "length": 192, "header": "tr|A0AAA9TUA7-1|A0AAA9TUA7_BOVIN Isoform 1 of Large ribosomal subunit protein uL6 OS=Bos taurus OX=9913 GN=LOC107132967 PE=3 SV=1 CANONICAL=A0AAA9TUA7-1" }, "isoforms": [ { "isoform_ac": "A0AAA9TUA7-1", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TUA7/entry", "sequence": { "sequence": "MKTILSNQTVDIPENVDINLKGRTVIVKGPRGTLRRDFNHINVELSLLGKKKKRLRVDKWWGNRKELATVLTICSHVQNMIKGVTLGFRYKMRSVYAHFPINVVIQENGSLVEIRNFLGEKYIRRVRMRPGVACSVSQAQKDELILEGNDIELVSNSAALIQQATTVKNKDIRKFLDGIYVSEKGTVQQADE", "length": 192, "header": "tr|A0AAA9TUA7-1|A0AAA9TUA7_BOVIN Isoform 1 of Large ribosomal subunit protein uL6 OS=Bos taurus OX=9913 GN=LOC107132967 PE=3 SV=1 CANONICAL=A0AAA9TUA7-1" }, "locus": { "chromosome": "11", "start_pos": 104133394, "end_pos": 104132819, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000101885.1", "url": "https://www.ensembl.org/id/ENSBTAT00000101885.1" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000100140.1", "url": "https://www.ensembl.org/id/ENSBTAP00000100140.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [ { "id": "bta:107132967", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?bta:107132967", "resource": "KEGG Pathway" } ], "orthologs": [ { "uniprot_canonical_ac": "P17077-1", "protein_name": "Large ribosomal subunit protein uL6", "gene_name": "Rpl9", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MKTILSNQTVDIPENVDITLKGRTVIVKGPRGTLRRDFNHINVELSLLGKKKKRLRVDKWWGNRKELATVRTICSHVQNMIKGVTLGFRYKMRSVYAHFPINVVIQENGSLVEIRNFLGEKYIRRVRMRTGVACSVSQAQKDELILEGNDIELVSNSAALIQQATTVKNKDIRKFLDGIYVSEKGTVQQPDE", "length": 192 }, "evidence": [ { "id": "A0AAA9TUA7", "url": "https://omabrowser.org/oma/group/A0AAA9TUA7/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" } ], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 3, "go_terms": [ { "name": "cytoplasm", "id": "GO:0005737", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005737", "evidence": [ { "database": "UniProtKB", "id": "A0AAA9TUA7", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TUA7" } ], "pmid": "" }, { "name": "ribosome", "id": "GO:0005840", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005840", "evidence": [ { "database": "UniProtKB", "id": "A0AAA9TUA7", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TUA7" } ], "pmid": "" }, { "name": "ribonucleoprotein complex", "id": "GO:1990904", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:1990904", "evidence": [ { "database": "UniProtKB", "id": "A0AAA9TUA7", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TUA7" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 1, "go_terms": [ { "name": "translation", "id": "GO:0006412", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006412", "evidence": [ { "database": "UniProtKB", "id": "A0AAA9TUA7", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TUA7" } ], "pmid": "" } ] }, { "name": "Molecular Function", "total": 2, "go_terms": [ { "name": "rRNA binding", "id": "GO:0019843", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0019843", "evidence": [ { "database": "UniProtKB", "id": "A0AAA9TUA7", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TUA7" } ], "pmid": "" }, { "name": "structural constituent of ribosome", "id": "GO:0003735", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003735", "evidence": [ { "database": "UniProtKB", "id": "A0AAA9TUA7", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TUA7" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 108, "end_pos": 110, "annotation": "n_glycosylation_sequon" }, { "start_pos": 7, "end_pos": 9, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A0AAA9TUA7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TUA7" }, { "id": "PF00347", "database": "Pfam", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00347" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "Large ribosomal subunit protein uL6 alpha-beta", "eco_id": "ECO_0000259", "start_pos": 12, "end_pos": 85, "start_aa": "Ile", "end_aa": "Thr", "glycosite_overlap": [] } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "homologset.oma", "label": "OMA Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 108, "end_pos": 110 }, { "start_pos": 7, "end_pos": 9 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ], "tool_support": { "graph_view": "yes" } }, { "uniprot_canonical_ac": "A0AAA9TUJ1-1", "uniprot_ac": "A0AAA9TUJ1", "uniprot_id": "A0AAA9TUJ1_BOVIN", "mass": { "chemical_mass": 33205.0, "monoisotopic_mass": 33205.0 }, "refseq": {}, "gene_names": [ { "name": "TMEM98", "type": "recommended", "evidence": [ { "id": "A0AAA9TUJ1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TUJ1" } ] } ], "protein_names": [ { "name": "Transmembrane protein 98", "type": "recommended", "evidence": [ { "id": "A0AAA9TUJ1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TUJ1/entry#names_and_taxonomy" } ] } ], "function": [ { "annotation": "Functions as a negative regulator of MYRF in oligodendrocyte differentiation and myelination. Interacts with the C-terminal of MYRF inhibiting MYRF self-cleavage and N-fragment nuclear translocation. The secreted form promotes differentiation of T helper 1 cells (Th1).", "evidence": [ { "database": "UniProtKB", "id": "A0AAA9TUJ1", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TUJ1#function" }, { "database": "UniProtKB", "id": "ARBA00059000", "url": "https://www.uniprot.org/uniprotkb/ARBA00059000#function" }, { "database": "UniProtKB", "id": "F1MX62", "url": "https://www.uniprot.org/uniprotkb/F1MX62#function" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Bos taurus", "taxid": 9913, "evidence": [ { "database": "UniProtKB", "id": "A0AAA9TUJ1", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TUJ1" } ], "common_name": "Bovine", "glygen_name": "Bovine", "reference_species": "Bos taurus [9913]" } ], "gene": [ { "name": "TMEM98", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TUJ1", "locus": { "chromosome": "19", "start_pos": 17287825, "end_pos": 17300869, "strand": "+", "evidence": [ { "database": "Ensembl Gene", "id": "ENSBTAG00000008913", "url": "https://www.ensembl.org/id/ENSBTAG00000008913" } ] } } ], "crossref": [ { "id": "A0AAA9TUJ1", "url": "https://alphafold.ebi.ac.uk/entry/A0AAA9TUJ1", "database": "AlphaFoldDB", "categories": [] }, { "id": "ENSBTAG00000008913", "url": "https://bgee.org/?page=gene&gene_id=ENSBTAG00000008913", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "513445", "url": "https://www.ncbi.nlm.nih.gov/gene/513445", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR029668", "url": "https://www.ebi.ac.uk/interpro/entry/IPR029668", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "HMEVIRE", "url": "https://omabrowser.org/oma/group/HMEVIRE/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "F1MX62", "url": "https://www.orthodb.org/?gene=F1MX62", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR32510", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR32510", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR32510:SF3", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR32510:SF3", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF28128", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF28128", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "A0AAA9TUJ1", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TUJ1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0AAA9TUJ1-1", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TUJ1-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "F1MX62", "url": "https://www.uniprot.org/uniprotkb/F1MX62", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "F1MX62-1", "url": "https://www.uniprot.org/uniprotkb/F1MX62-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MRGRGALPNPRGRPVPRRPLPAPPGPRGGAGTARRVAERLPRSCPGPLAAPTPGRPGGLAVTAAPGSGGFGCSARGSPARAAAGGLAARTYLRAFPACPARRRPPVPRPDSAIAGGPAAGAPPPASRSRSRSRSRRPIVDLIGAMETQSEPSELELDDVVITNPHIEAILENEDWIEDASGLMSHCIAILKICHTLTEKLVAMTMGSGAKMKTSASVSDIIVVAKRISPRVDDVVKSMYPPLDPKLLDARTTALLLSVSHLVLVTRNACHLTGGLDWIDQSLTAAEEHLEVLREAALASEPDKGLPGPEGFLQEQSAI", "length": 318, "header": "tr|A0AAA9TUJ1-1|A0AAA9TUJ1_BOVIN Isoform 1 of Transmembrane protein 98 OS=Bos taurus OX=9913 GN=TMEM98 PE=3 SV=1 CANONICAL=A0AAA9TUJ1-1" }, "isoforms": [ { "isoform_ac": "A0AAA9TUJ1-1", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TUJ1/entry", "sequence": { "sequence": "MRGRGALPNPRGRPVPRRPLPAPPGPRGGAGTARRVAERLPRSCPGPLAAPTPGRPGGLAVTAAPGSGGFGCSARGSPARAAAGGLAARTYLRAFPACPARRRPPVPRPDSAIAGGPAAGAPPPASRSRSRSRSRRPIVDLIGAMETQSEPSELELDDVVITNPHIEAILENEDWIEDASGLMSHCIAILKICHTLTEKLVAMTMGSGAKMKTSASVSDIIVVAKRISPRVDDVVKSMYPPLDPKLLDARTTALLLSVSHLVLVTRNACHLTGGLDWIDQSLTAAEEHLEVLREAALASEPDKGLPGPEGFLQEQSAI", "length": 318, "header": "tr|A0AAA9TUJ1-1|A0AAA9TUJ1_BOVIN Isoform 1 of Transmembrane protein 98 OS=Bos taurus OX=9913 GN=TMEM98 PE=3 SV=1 CANONICAL=A0AAA9TUJ1-1" }, "locus": { "chromosome": "19", "start_pos": 17300843, "end_pos": 17288466, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000122241.1", "url": "https://www.ensembl.org/id/ENSBTAT00000122241.1" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000102037.1", "url": "https://www.ensembl.org/id/ENSBTAP00000102037.1" } ] } }, { "isoform_ac": "F1MX62-1", "url": "https://www.uniprot.org/uniprotkb/F1MX62/entry", "sequence": { "sequence": "METVVIVAIGVLATIFLASFAALVVVCRQRYCRPRDLLQCYDSKPIVDLIGAMETQSEPSELELDDVVITNPHIEAILENEDWIEDASGLMSHCIAILKICHTLTEKLVAMTMGSGAKMKTSASVSDIIVVAKRISPRVDDVVKSMYPPLDPKLLDARTTALLLSVSHLVLVTRNACHLTGGLDWIDQSLTAAEEHLEVLREAALASEPDKGLPGPEGFLQEQSAI", "length": 226, "header": "tr|F1MX62-1|F1MX62_BOVIN Computationally mapped isoform of Transmembrane protein 98 OS=Bos taurus OX=9913 GN=TMEM98 PE=3 SV=1 CANONICAL=A0AAA9TUJ1-1" }, "locus": { "chromosome": "19", "start_pos": 17298234, "end_pos": 17288466, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000011732.5", "url": "https://www.ensembl.org/id/ENSBTAT00000011732.5" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000011732.4", "url": "https://www.ensembl.org/id/ENSBTAP00000011732.4" } ] } } ], "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "other", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 52, "start_aa": "Thr", "end_pos": 52, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr52", "evidence": [ { "id": "", "database": "GlyGen", "url": "https://data.glygen.org/" } ], "filter_code": "000000000000000010000.00000000001000.0.01000" } ], "phosphorylation": [], "glycation": [], "keywords": [ "glycoprotein", "glycoprotein_predicted" ], "publication": [], "pathway": [], "orthologs": [ { "uniprot_canonical_ac": "A0A8V0ZVE9-1", "protein_name": "Transmembrane protein 98", "gene_name": "TMEM98", "tax_id": 9031, "organism": "Gallus gallus", "sequence": { "sequence": "METVVIVAIGVLATIFLASFVALVVVCRQRYCRPKDLLHPYDTKPIVDLIGAMETQSEPSELELDDVVITNPHIEAILENEDWIEDASGLVSHCIAILKICHTLTEKLVAMTMGSGARAKSPSSLGDIIVVAKRISPRVDDVVRSMYPPLDPKLLDARAAALLLSVSHLVLVARSACPQPGDRDWVDRSLAAAERHMAALRHAAMATEPERSAAAEPFRQEQSAI", "length": 225 }, "evidence": [ { "id": "A0AAA9TUJ1", "url": "https://omabrowser.org/oma/group/A0AAA9TUJ1/", "database": "OMA" } ], "glygen_name": "Chicken", "common_name": "Chicken" }, { "uniprot_canonical_ac": "G3GTS8-1", "protein_name": "Transmembrane protein 98", "gene_name": "Tmem98", "tax_id": 10029, "organism": "Cricetulus griseus", "sequence": { "sequence": "METVVIVAIGVLATIFLASFAALVVVCRQRYCRPRDLLQRYDSKPIVDLIGAMETQSEPSELELDDVVITNPHIEAILENEDWIEDASGLMSHCIAILKICHTLTEKLVAMTMGSGAKMKTSASVSDIIVVAKRISPRVDDVVKSMYPPLDPKLLDARTTALLLSVSHLVLVTRNACHLTGGLDWIDQSLSAAEEHLEVLREAALASEPDKSLPNPEGFLQEQSAI", "length": 226 }, "evidence": [ { "id": "A0AAA9TUJ1", "url": "https://omabrowser.org/oma/group/A0AAA9TUJ1/", "database": "OMA" } ], "glygen_name": "Hamster", "common_name": "Chinese hamster" }, { "uniprot_canonical_ac": "Q6AYS5-1", "protein_name": "Transmembrane protein 98", "gene_name": "Tmem98", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "METVVIVAIGVLATIFLASFAALVVVCRQRYCRPRDLLQRYDSKPIVDLIGAMETQSEPSELELDDVVITNPHIEAILENEDWIEDASGLMSHCIAILKICHTLTEKLVAMTMGSGAKMKTSASVSDIIVVAKRISPRVDDVVKSMYPPLDPKLLDARTTALLLSVSHLVLVTRNACHLTGGLDWIDQSLSAAEEHLEVLREAALASEPDKSLPNPEGFLQEQSAI", "length": 226 }, "evidence": [ { "id": "A0AAA9TUJ1", "url": "https://omabrowser.org/oma/group/A0AAA9TUJ1/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "Q91X86-1", "protein_name": "Transmembrane protein 98", "gene_name": "Tmem98", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "METVVIVAIGVLATIFLASFAALVVVCRQRYCRPRDLLQRYDSKPIVDLIGAMETQSEPSELELDDVVITNPHIEAILENEDWIEDASGLMSHCIAILKICHTLTEKLVAMTMGSGAKMKTSASVSDIIVVAKRISPRVDDVVKSMYPPLDPKLLDARTTALLLSVSHLVLVTRNACHLTGGLDWIDQSLSAAEEHLEVLREAALASEPDKSLPNPEGFLQEQSAI", "length": 226 }, "evidence": [ { "id": "A0AAA9TUJ1", "url": "https://omabrowser.org/oma/group/A0AAA9TUJ1/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q9Y2Y6-1", "protein_name": "Transmembrane protein 98", "gene_name": "TMEM98", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "METVVIVAIGVLATIFLASFAALVLVCRQRYCRPRDLLQRYDSKPIVDLIGAMETQSEPSELELDDVVITNPHIEAILENEDWIEDASGLMSHCIAILKICHTLTEKLVAMTMGSGAKMKTSASVSDIIVVAKRISPRVDDVVKSMYPPLDPKLLDARTTALLLSVSHLVLVTRNACHLTGGLDWIDQSLSAAEEHLEVLREAALASEPDKGLPGPEGFLQEQSAI", "length": 226 }, "evidence": [ { "id": "A0AAA9TUJ1", "url": "https://omabrowser.org/oma/group/A0AAA9TUJ1/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" } ], "go_annotation": { "categories": [ { "name": "Biological Process", "total": 5, "go_terms": [ { "name": "T-helper 1 cell differentiation", "id": "GO:0045063", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0045063", "evidence": [ { "database": "UniProtKB", "id": "A0AAA9TUJ1", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TUJ1" } ], "pmid": "" }, { "name": "negative regulation of protein localization to nucleus", "id": "GO:1900181", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:1900181", "evidence": [ { "database": "UniProtKB", "id": "A0AAA9TUJ1", "url": 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Transports a range of endogenous molecules that have a key role in cellular communication and signaling, including cyclic nucleotides such as cyclic AMP (cAMP) and cyclic GMP (cGMP), bile acids, steroid conjugates, urate, and prostaglandins. Mediates the ATP-dependent efflux of glutathione conjugates such as leukotriene C4 (LTC4) and leukotriene B4 (LTB4) too. The presence of GSH is necessary for the ATP-dependent transport of LTB4, whereas GSH is not required for the transport of LTC4. Mediates the cotransport of bile acids with reduced glutathione (GSH). Transports a wide range of drugs and their metabolites, including anticancer, antiviral and antibiotic molecules. 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"https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd03250", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "cd18593", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd18593", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "cd18601", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd18601", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "IPR003439", "url": "https://www.ebi.ac.uk/interpro/entry/IPR003439", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR003593", "url": "https://www.ebi.ac.uk/interpro/entry/IPR003593", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR011527", "url": "https://www.ebi.ac.uk/interpro/entry/IPR011527", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR017871", "url": "https://www.ebi.ac.uk/interpro/entry/IPR017871", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR027417", "url": "https://www.ebi.ac.uk/interpro/entry/IPR027417", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR030240", "url": "https://www.ebi.ac.uk/interpro/entry/IPR030240", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR036640", "url": "https://www.ebi.ac.uk/interpro/entry/IPR036640", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR047083", "url": "https://www.ebi.ac.uk/interpro/entry/IPR047083", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR050173", "url": "https://www.ebi.ac.uk/interpro/entry/IPR050173", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "PTHR24223", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR24223", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR24223:SF357", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR24223:SF357", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00005", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00005", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF00664", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00664", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "66424", "url": "https://www.rhea-db.org/rhea/66424", "database": "Rhea", "categories": [ "Enzyme and Pathway" ] }, { "id": "A0AAA9TUR1", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TUR1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0AAA9TUR1-1", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TUR1-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MPAVASRSSGSLTVARAALRRSTPAPACTMPLLYPKPNPLQKANLCSRLFFWWLNPLFKIGHKRKLEANDMYSVLPEDRSQHLGEELQGYWDQEVLRAQKDAREPSLMKAIIKCYGKSYLVWGMLTFLEEGTRVVQPIFLGKMISYFENYNPTDSAALHEAYGYAAGLSACVLLWAVLHHLYFYHMQRVGMRLRVAVCHMIYRKTLRLSSSAMGKTTTGQIVNLLSNDVNRFDQVTTLLHYLWVGPLQVIAVTALLWMEIGMSCLAGMAVLIILLLLQSCFGMSFSSLRSRTAALTDDRIRTMSEVITGIRTVKMNVWEQSFINLITRLGRKEISKILRSSYLRAMNLTSFFAVSKIMIFVTFIANELLDNLITASQVFVVVMLFEALRFSSTLYFPMAIEKVSEAVVSIRRIKNFLLLDEVSQCYPQLPSDGKTIVDVQAFSASWEKTSETPTLQGLSFTVRPGELLAVIGPVGAGKSSLLHALLGELPLSQGKVSIHGRIAYVSQQPWLFPGTVKSNILFGKKYDKERYEKVIEACDLKNDLQLLEEGDLTEIGDRGTPLSEGQKARVSLARAVYQDADIYLLDDPLSAVDVGVSRHLFEQCVCQALKDKITILVTHQLQHLKDASQILVLKDGITVERGTYSEFLKSGIDIFSLFEKGNEQSEPSPVPGAPSLISESLVQSFKSPRPSLKDAAQEDQETENIQVTLPVEDHLEGKVGFKTYKNYFTAGADWPIIIFFILVNIAAQVAYVLQDWWLAFWANVQNDLYFGVYVKEDEDVVFVLNWYLSVYSGLTVSTVLFGITRSLLIVYILVNSSRALHNKMLESILRAPVLFFHRNPIGRILNRFSKDVGHMDDLLPLIFLDFIQTFLLVIGVVGVMVAAIPWTAIPVIPLGIIFFFLRRYFLETSRDVKRLECTTRSPVFSHLASSLRGLWTIRAYKAEQKFLELFDAHQDLHSEAWFLLLTTSRWLAVYLDVICAIFVTAVAFGALILVETLDAGHVGLILSLTITLISIFQWCVRQSAEAENTMISVERVIEYTDLVKEASWELVYRPPPSWPNKGMISFYDVNFRHMLDRPLVLKNLYPDFHPRQKVGIVGRTGAGKSSLIAALFRLSEPGGRIYIDDILTTSIGLHDLRKKMSVALQEPVLFTGTMRENLDPFNDHTDNELWNALEEVQLKESIEGLPAKMNTELAESGLNLSVGQKQLVCLARALLRKNQILIIDKATSNVDPRTDEFIQKRIRERFAQCTVLTIAHRLSTVIDCEWIMVLDSGTEKEYNRTHNLLRDRNSLFYKMVQQLGEAEAAVLTKRAI", "length": 1312, "header": "tr|A0AAA9TUR1-1|A0AAA9TUR1_BOVIN Isoform 1 of Multidrug resistance-associated protein 4 OS=Bos taurus OX=9913 GN=LOC528412 PE=3 SV=1 CANONICAL=A0AAA9TUR1-1" }, "isoforms": [ { "isoform_ac": "A0AAA9TUR1-1", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TUR1/entry", "sequence": { "sequence": "MPAVASRSSGSLTVARAALRRSTPAPACTMPLLYPKPNPLQKANLCSRLFFWWLNPLFKIGHKRKLEANDMYSVLPEDRSQHLGEELQGYWDQEVLRAQKDAREPSLMKAIIKCYGKSYLVWGMLTFLEEGTRVVQPIFLGKMISYFENYNPTDSAALHEAYGYAAGLSACVLLWAVLHHLYFYHMQRVGMRLRVAVCHMIYRKTLRLSSSAMGKTTTGQIVNLLSNDVNRFDQVTTLLHYLWVGPLQVIAVTALLWMEIGMSCLAGMAVLIILLLLQSCFGMSFSSLRSRTAALTDDRIRTMSEVITGIRTVKMNVWEQSFINLITRLGRKEISKILRSSYLRAMNLTSFFAVSKIMIFVTFIANELLDNLITASQVFVVVMLFEALRFSSTLYFPMAIEKVSEAVVSIRRIKNFLLLDEVSQCYPQLPSDGKTIVDVQAFSASWEKTSETPTLQGLSFTVRPGELLAVIGPVGAGKSSLLHALLGELPLSQGKVSIHGRIAYVSQQPWLFPGTVKSNILFGKKYDKERYEKVIEACDLKNDLQLLEEGDLTEIGDRGTPLSEGQKARVSLARAVYQDADIYLLDDPLSAVDVGVSRHLFEQCVCQALKDKITILVTHQLQHLKDASQILVLKDGITVERGTYSEFLKSGIDIFSLFEKGNEQSEPSPVPGAPSLISESLVQSFKSPRPSLKDAAQEDQETENIQVTLPVEDHLEGKVGFKTYKNYFTAGADWPIIIFFILVNIAAQVAYVLQDWWLAFWANVQNDLYFGVYVKEDEDVVFVLNWYLSVYSGLTVSTVLFGITRSLLIVYILVNSSRALHNKMLESILRAPVLFFHRNPIGRILNRFSKDVGHMDDLLPLIFLDFIQTFLLVIGVVGVMVAAIPWTAIPVIPLGIIFFFLRRYFLETSRDVKRLECTTRSPVFSHLASSLRGLWTIRAYKAEQKFLELFDAHQDLHSEAWFLLLTTSRWLAVYLDVICAIFVTAVAFGALILVETLDAGHVGLILSLTITLISIFQWCVRQSAEAENTMISVERVIEYTDLVKEASWELVYRPPPSWPNKGMISFYDVNFRHMLDRPLVLKNLYPDFHPRQKVGIVGRTGAGKSSLIAALFRLSEPGGRIYIDDILTTSIGLHDLRKKMSVALQEPVLFTGTMRENLDPFNDHTDNELWNALEEVQLKESIEGLPAKMNTELAESGLNLSVGQKQLVCLARALLRKNQILIIDKATSNVDPRTDEFIQKRIRERFAQCTVLTIAHRLSTVIDCEWIMVLDSGTEKEYNRTHNLLRDRNSLFYKMVQQLGEAEAAVLTKRAI", "length": 1312, "header": "tr|A0AAA9TUR1-1|A0AAA9TUR1_BOVIN Isoform 1 of Multidrug resistance-associated protein 4 OS=Bos taurus OX=9913 GN=LOC528412 PE=3 SV=1 CANONICAL=A0AAA9TUR1-1" }, "locus": { "chromosome": "NKLS02001928.1", "start_pos": 694106, "end_pos": 494883, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000128734.1", "url": "https://www.ensembl.org/id/ENSBTAT00000128734.1" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000101089.1", "url": "https://www.ensembl.org/id/ENSBTAP00000101089.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [ "enzyme" ], "publication": [], "pathway": [], "orthologs": [], "go_annotation": { "categories": [ { "name": "Molecular Function", "total": 4, "go_terms": [ { "name": "ATP binding", "id": "GO:0005524", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005524", "evidence": [ { "database": "UniProtKB", "id": "A0AAA9TUR1", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TUR1" } ], "pmid": "" }, { "name": "ABC-type xenobiotic transporter activity", "id": "GO:0008559", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008559", "evidence": [ { "database": "UniProtKB", "id": "A0AAA9TUR1", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TUR1" } ], "pmid": "" }, { "name": "ATP hydrolysis activity", "id": "GO:0016887", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016887", "evidence": [ { "database": "UniProtKB", "id": "A0AAA9TUR1", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TUR1" } ], "pmid": "" }, { "name": "ABC-type glutathione S-conjugate transporter activity", "id": "GO:0015431", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0015431", "evidence": [ { "database": "UniProtKB", "id": "A0AAA9TUR1", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TUR1" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 1, "go_terms": [ { "name": "lipid transport", "id": "GO:0006869", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006869", "evidence": [ { "database": "UniProtKB", "id": "A0AAA9TUR1", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TUR1" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 2, "go_terms": [ { "name": "basolateral plasma membrane", "id": "GO:0016323", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016323", "evidence": [ { "database": "UniProtKB", "id": "A0AAA9TUR1", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TUR1" } ], "pmid": "" }, { "name": "apical plasma membrane", "id": "GO:0016324", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016324", "evidence": [ { "database": "UniProtKB", "id": "A0AAA9TUR1", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TUR1" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 1199, "end_pos": 1201, "annotation": "n_glycosylation_sequon" }, { "start_pos": 1279, "end_pos": 1281, "annotation": "n_glycosylation_sequon" }, { "start_pos": 347, "end_pos": 349, "annotation": "n_glycosylation_sequon" }, { "start_pos": 815, "end_pos": 817, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [ { "id": "66424", "name": "", "equation": "leukotriene B4(in) + ATP + H2O = leukotriene B4(out) + ADP + phosphate + H(+)", "summary": "", "cellular_location": "", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [ "A0AAA9RZT1-1", "A0AAA9T569-1", "A0AAA9SJG6-1", "A0AAA9TUR1-1", "A0AAA9S3M4-1", "G3MW08-1", "A0AAA9TZ11-1", "A0A3Q1LXZ2-1", "A0AAA9T4S3-1", "A0A3Q1LPI1-1", "A0AAA9TR50-1", "A0A3Q1ML89-1", "A0AAA9SMB4-1" ], "evidence": [ { "id": "66424", "database": "Rhea", "url": "https://www.rhea-db.org/rhea/66424" } ] } ], "reaction_participants": [], "reaction_enzymes": [ { "uniprot_ac": "A0A3Q1LPI1", "gene_name": "LOC107131247", "activity": [ { "ec_number": "7.6.2.2", "activity": "daunorubicin(in) + ATP + H2O = daunorubicin(out) + ADP + phosphate + H(+).", "evidence": [ { "id": "A0A3Q1LPI1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1LPI1" } ] }, { "ec_number": "7.6.2.3", "activity": "an S-substituted glutathione(in) + ATP + H2O = an S-substituted glutathione(out) + ADP + phosphate + H(+).", "evidence": [ { "id": "A0A3Q1LPI1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1LPI1" } ] }, { "ec_number": "7.6.2.2", "activity": "", "evidence": [ { "id": "A0A3Q1LPI1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1LPI1" } ] }, { "ec_number": "7.6.2.3", "activity": "", "evidence": [ { "id": "A0A3Q1LPI1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1LPI1" } ] } ] }, { "uniprot_ac": "A0A3Q1LXZ2", "gene_name": "LOC521568", "activity": [ { "ec_number": "7.6.2.2", "activity": "daunorubicin(in) + ATP + H2O = daunorubicin(out) + ADP + phosphate + H(+).", "evidence": [ { "id": "A0A3Q1LXZ2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1LXZ2" } ] }, { "ec_number": "7.6.2.3", "activity": "an S-substituted glutathione(in) + ATP + H2O = an S-substituted glutathione(out) + ADP + phosphate + H(+).", "evidence": [ { "id": "A0A3Q1LXZ2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1LXZ2" } ] }, { "ec_number": "7.6.2.3", "activity": "", "evidence": [ { "id": "A0A3Q1LXZ2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1LXZ2" } ] }, { "ec_number": "7.6.2.2", "activity": "", "evidence": [ { "id": "A0A3Q1LXZ2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1LXZ2" } ] } ] }, { "uniprot_ac": "A0A3Q1ML89", "gene_name": "LOC100299180", "activity": [ { "ec_number": "7.6.2.2", "activity": "daunorubicin(in) + ATP + H2O = daunorubicin(out) + ADP + phosphate + H(+).", "evidence": [ { "id": "A0A3Q1ML89", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1ML89" } ] }, { "ec_number": "7.6.2.3", "activity": "an S-substituted glutathione(in) + ATP + H2O = an S-substituted glutathione(out) + ADP + phosphate + H(+).", "evidence": [ { "id": "A0A3Q1ML89", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1ML89" } ] }, { "ec_number": "7.6.2.3", "activity": "", "evidence": [ { "id": "A0A3Q1ML89", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1ML89" } ] }, { "ec_number": "7.6.2.2", "activity": "", "evidence": [ { "id": "A0A3Q1ML89", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1ML89" } ] } ] }, { "uniprot_ac": "A0AAA9RZT1", "gene_name": "LOC100337390", "activity": [ { "ec_number": "7.6.2.2", "activity": "daunorubicin(in) + ATP + H2O = daunorubicin(out) + ADP + phosphate + H(+).", "evidence": [ { "id": "A0AAA9RZT1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9RZT1" } ] }, { "ec_number": "7.6.2.3", "activity": "an S-substituted glutathione(in) + ATP + H2O = an S-substituted glutathione(out) + ADP + phosphate + H(+).", "evidence": [ { "id": "A0AAA9RZT1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9RZT1" } ] }, { "ec_number": "7.6.2.3", "activity": "", "evidence": [ { "id": "A0AAA9RZT1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9RZT1" } ] }, { "ec_number": "7.6.2.2", "activity": "", "evidence": [ { "id": "A0AAA9RZT1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9RZT1" } ] } ] }, { "uniprot_ac": "A0AAA9S3M4", "gene_name": "LOC100848700", "activity": [ { "ec_number": "7.6.2.2", "activity": "daunorubicin(in) + ATP + H2O = daunorubicin(out) + ADP + phosphate + H(+).", "evidence": [ { "id": "A0AAA9S3M4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9S3M4" } ] }, { "ec_number": "7.6.2.3", "activity": "an S-substituted glutathione(in) + ATP + H2O = an S-substituted glutathione(out) + ADP + phosphate + H(+).", "evidence": [ { "id": "A0AAA9S3M4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9S3M4" } ] }, { "ec_number": "7.6.2.2", "activity": "", "evidence": [ { "id": "A0AAA9S3M4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9S3M4" } ] }, { "ec_number": "7.6.2.3", "activity": "", "evidence": [ { "id": "A0AAA9S3M4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9S3M4" } ] } ] }, { "uniprot_ac": "A0AAA9SJG6", "gene_name": "LOC101906567", "activity": [ { "ec_number": "7.6.2.2", "activity": "daunorubicin(in) + ATP + H2O = daunorubicin(out) + ADP + phosphate + H(+).", "evidence": [ { "id": "A0AAA9SJG6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9SJG6" } ] }, { "ec_number": "7.6.2.3", "activity": "an S-substituted glutathione(in) + ATP + H2O = an S-substituted glutathione(out) + ADP + phosphate + H(+).", "evidence": [ { "id": "A0AAA9SJG6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9SJG6" } ] }, { 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"MGNAPSHSSEDEAAAAGGEGWGPHQDWAADSGTTPGQGPAAPALPPAAALLEPARLREAAAALRPTPPCESLVSRHHGALLRWLEERLGRGEESVTLEQFGELLEARGAGFSGERFEEAFAQFDAEGDGTVDAENMLEALKNSSGANLQGELSHIIRQLQACSLVPGFIDIFSESKEGLDVHAAMILRFLHRNRLSSTVIPYPMLDHCNNMSTMRASVLRESLDQLVQKEKESPGDLTRSPEMDKLKSVAKCYAYIETSSNPADIDKMTNGETSSYWQSDGSARSHWIRLKMKPDVVLRHLSIAVAATDQSYMPQQVTVAVGRTASDLQEVRDVHIPSNVTGYVTLLENANISQLYVQINIKRCLSDGCDTRIHGLRAVGFQRVKKSGVSVSDASAIWYWSLLTSLVTASMETNPAFVQTVLRNTQKALQHMPPLSLSPGSTDFSTFLSPNVLEEVDSFLIRITSCRSTPEVELTLLAFALARGSVAKVLSSLCTVTDHLDTHYDASSLISSMASVRQNLLLKYGKPLQLTLQACDVKGKEEKSGPENLLAEPWTRDGFLTETGKTRASTIFSTGTESAFQVTQIRIMVRRGGIGAQCGLVFAYNSSSDKFHAEEHFKRFEKYDKWKLQEFRQFVKSRIGCSSDILGEDDPIGWFELEEEWDEADVKLQQCRVAKYLMVKFLCTRQESAERLGVQGLSISGYLRPARAEAEQSIVCAHCRKSTEESVCGATLLLKTLQFIQQLAHDLVQQKESGLKYKSFLDFAGLDLQIFWNFYSKLKQNPREECICAQTLLLQLLQSCFSVLQGDAPAAAEDAKAPSPRPRPVEAAKELYAHLCSVVDRLDGDSVPMEILKQEVRNTLLNGAAIFFPDRLTRRNHLFTMMKNVTEQEHKQSMQLTFRSLCTYFSDKDPGGLLLLPEKGDLADMDISEVLAVMNTLLSVAARECELLMVDGAQREVGSVLSSLFWSVQGSLLSWCYLQLKSTDSGAKDLAADLTDRYVGQFLAHVRVILESLLSQYSGKTIVEKLCNSVFSMAARQLVIFLLDFCTLDISHCTLLREFSALTELLKELCSDPEGGVNKLDVETWQQERPVVLHTWTKESAHNYENNCHEVSVFVSPGATYFEVEFDERCETEKRYDYLEFTDARGGKTRYDTKVGTDKWPKKVTFKAGPRLQFLFHSDSSNNEWGYKFTVTAYGLPDVAVSWGLDLQLLVSRLMGRLASQCMALKSVHQLGSNMAVPQAKMALVLNSPLWKPVFRHQIHPELGLEASWPTHPPQDNKEVKNIPDDHCHQFLLDFAQSDPAQNFCGPYSELFKGFIQACRKQAPKTDIVAGSTIDQAVNATFAALVYRTPDLYEKLQKYVNSGGKTALSEEFAQVYSLADGIRIWMLEMKQKSLMNLGSEAEEQRDPEAAEANPESLAKECYQKSLLLLKFLPTGGGSKESCDRSVAVDDTDHLQPLDKRQRTSSVVEEHFQASASPTEAAPPTAGDRSPGPDMQPTLPPSSGAPALEVSSVPAEEPSSPSTPTRRPPFTRGRLRLLSFRSMEEARPAPTVKEKYPVLKDLMDFIKDQSLSHESVVKVLSLRKAQAWSILEVLRIIQCCTESLGQPHCFHPPYILFLLELLTCQKEFTNYFGHLEGCGADLHKEIRDTYYQFVLFLVKAVKGFNSKNDRSLLPALSCIQTALLHLLDMGWEPSDLTFFVDIQLPDLLMKMSQENISAHDSVISQWSEEDELADAKQNSEWMDECQDGMFEAWYEKIAQEDPEKQRKMHMFIARYCDLLNVDISCDGCDEIAPWHRYRCLQCSDMDLCKTCFLGGVKPEGHGDDHEMVNMEFTCDHCQGLIIGRRMHCNVCDDFDLCYGCYAAKKYSYGHLPTHSITAHPMVTIRISDRQRLIQPYIHNYSWLLFAALALYSAHLASAEDVDGEKLDPQVRSSAATLRSRCLQLVGDCLMKAHQGKGLKALALLGVLPDGGSPPENQALPVTAPTQTSEEQPEKKAVQAAAEPAPTGPAGPRSGKRDGPKEVRPLDCKQRSKASEGVSLRKDPSCPPQISDSPADACTPTGLPDAENSEASSQKPIEEKAVIPSPEQVFAECSQKRILGLLAAMLPPLNSDPTVPLIDLEHVLPLMFQVVISNAGHLNETYHLTLGLLGQLIIRLLPAEVDAAVTKVLSAKHNLFAAGDSSVVPDGWKTTHLLFSLGAVCLDSRVGLDWACSMAEILRSLNSAPLWRDVVATFTDHCIKQLPFQLKHTNIFTLLVLVGFPQVLCVGTRCVYMDNANEPHNVIILKHFTEKNRAVIVDVKTRKRKTVKDYQLVQKGGGQEGSDSQAQLSQYSQHFAFIASHLLQTSMDSHCPEAVEATWVLSLALKGLYKTLKVHGFEETHATFLQTDLLKLLVKKCSKGTGFSKTWLLRDLEILSIMLYSSKKEINTLAEHGELELDERGDQEEEVERSVSSPGDQEQKKLDPLESLDEPTRICFLMAHDALNAPLHILRAIYELQMKRTDSFFLEVQKRFDGDELTTDERIRTLAQRWQPSRSLRLDEQSAKAVDTDMIILPCLSRPVRCEQATVESNPVTQKLISSTDSELQQSYAKQRRSKSAALLHKELNCKSKRAVREYLFRVNEATAVLYARHVLASLLAEWPGHVPVSEDILELSGPAHMTYILDMFMQLEDRHQWEKILQKVLQGCRESMLGTMALAACQFMEEPGMEVQVRESKHPYNNNTNFEDKVHIPGAIYLSIKFDPQCNTEEGCDELAMSSSSDFQQDRHNFSGSQQKWKDFELPGDTLYYRFTSDMSNTEWGYRFTVTAGHLGRFQTGFEILKQMLSEERVVPYLPLAKIWEWLVGVACRQTGHQRLKAIHLLLRIVRCCTHSDLCDLTLLKPLWQLFTQMEYSLFEDVTQAGILLPLHRALTELFFVTENRAQELGLLQDYLLALTTDDHLLRCAAQVMTGDALISRKDLPLTPEESHDWFESLSGFLVLNGALLLLSEVLNSVWRHCPGFTGISSVTS", "length": 3004, "header": "tr|A0AAA9TUR4-1|A0AAA9TUR4_BOVIN Isoform 1 of Zinc finger ZZ-type and EF-hand domain containing 1 OS=Bos taurus OX=9913 GN=ZZEF1 PE=4 SV=1 CANONICAL=A0AAA9TUR4-1" }, "isoforms": [ { "isoform_ac": "A0AAA9TUR4-1", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TUR4/entry", "sequence": { "sequence": "MGNAPSHSSEDEAAAAGGEGWGPHQDWAADSGTTPGQGPAAPALPPAAALLEPARLREAAAALRPTPPCESLVSRHHGALLRWLEERLGRGEESVTLEQFGELLEARGAGFSGERFEEAFAQFDAEGDGTVDAENMLEALKNSSGANLQGELSHIIRQLQACSLVPGFIDIFSESKEGLDVHAAMILRFLHRNRLSSTVIPYPMLDHCNNMSTMRASVLRESLDQLVQKEKESPGDLTRSPEMDKLKSVAKCYAYIETSSNPADIDKMTNGETSSYWQSDGSARSHWIRLKMKPDVVLRHLSIAVAATDQSYMPQQVTVAVGRTASDLQEVRDVHIPSNVTGYVTLLENANISQLYVQINIKRCLSDGCDTRIHGLRAVGFQRVKKSGVSVSDASAIWYWSLLTSLVTASMETNPAFVQTVLRNTQKALQHMPPLSLSPGSTDFSTFLSPNVLEEVDSFLIRITSCRSTPEVELTLLAFALARGSVAKVLSSLCTVTDHLDTHYDASSLISSMASVRQNLLLKYGKPLQLTLQACDVKGKEEKSGPENLLAEPWTRDGFLTETGKTRASTIFSTGTESAFQVTQIRIMVRRGGIGAQCGLVFAYNSSSDKFHAEEHFKRFEKYDKWKLQEFRQFVKSRIGCSSDILGEDDPIGWFELEEEWDEADVKLQQCRVAKYLMVKFLCTRQESAERLGVQGLSISGYLRPARAEAEQSIVCAHCRKSTEESVCGATLLLKTLQFIQQLAHDLVQQKESGLKYKSFLDFAGLDLQIFWNFYSKLKQNPREECICAQTLLLQLLQSCFSVLQGDAPAAAEDAKAPSPRPRPVEAAKELYAHLCSVVDRLDGDSVPMEILKQEVRNTLLNGAAIFFPDRLTRRNHLFTMMKNVTEQEHKQSMQLTFRSLCTYFSDKDPGGLLLLPEKGDLADMDISEVLAVMNTLLSVAARECELLMVDGAQREVGSVLSSLFWSVQGSLLSWCYLQLKSTDSGAKDLAADLTDRYVGQFLAHVRVILESLLSQYSGKTIVEKLCNSVFSMAARQLVIFLLDFCTLDISHCTLLREFSALTELLKELCSDPEGGVNKLDVETWQQERPVVLHTWTKESAHNYENNCHEVSVFVSPGATYFEVEFDERCETEKRYDYLEFTDARGGKTRYDTKVGTDKWPKKVTFKAGPRLQFLFHSDSSNNEWGYKFTVTAYGLPDVAVSWGLDLQLLVSRLMGRLASQCMALKSVHQLGSNMAVPQAKMALVLNSPLWKPVFRHQIHPELGLEASWPTHPPQDNKEVKNIPDDHCHQFLLDFAQSDPAQNFCGPYSELFKGFIQACRKQAPKTDIVAGSTIDQAVNATFAALVYRTPDLYEKLQKYVNSGGKTALSEEFAQVYSLADGIRIWMLEMKQKSLMNLGSEAEEQRDPEAAEANPESLAKECYQKSLLLLKFLPTGGGSKESCDRSVAVDDTDHLQPLDKRQRTSSVVEEHFQASASPTEAAPPTAGDRSPGPDMQPTLPPSSGAPALEVSSVPAEEPSSPSTPTRRPPFTRGRLRLLSFRSMEEARPAPTVKEKYPVLKDLMDFIKDQSLSHESVVKVLSLRKAQAWSILEVLRIIQCCTESLGQPHCFHPPYILFLLELLTCQKEFTNYFGHLEGCGADLHKEIRDTYYQFVLFLVKAVKGFNSKNDRSLLPALSCIQTALLHLLDMGWEPSDLTFFVDIQLPDLLMKMSQENISAHDSVISQWSEEDELADAKQNSEWMDECQDGMFEAWYEKIAQEDPEKQRKMHMFIARYCDLLNVDISCDGCDEIAPWHRYRCLQCSDMDLCKTCFLGGVKPEGHGDDHEMVNMEFTCDHCQGLIIGRRMHCNVCDDFDLCYGCYAAKKYSYGHLPTHSITAHPMVTIRISDRQRLIQPYIHNYSWLLFAALALYSAHLASAEDVDGEKLDPQVRSSAATLRSRCLQLVGDCLMKAHQGKGLKALALLGVLPDGGSPPENQALPVTAPTQTSEEQPEKKAVQAAAEPAPTGPAGPRSGKRDGPKEVRPLDCKQRSKASEGVSLRKDPSCPPQISDSPADACTPTGLPDAENSEASSQKPIEEKAVIPSPEQVFAECSQKRILGLLAAMLPPLNSDPTVPLIDLEHVLPLMFQVVISNAGHLNETYHLTLGLLGQLIIRLLPAEVDAAVTKVLSAKHNLFAAGDSSVVPDGWKTTHLLFSLGAVCLDSRVGLDWACSMAEILRSLNSAPLWRDVVATFTDHCIKQLPFQLKHTNIFTLLVLVGFPQVLCVGTRCVYMDNANEPHNVIILKHFTEKNRAVIVDVKTRKRKTVKDYQLVQKGGGQEGSDSQAQLSQYSQHFAFIASHLLQTSMDSHCPEAVEATWVLSLALKGLYKTLKVHGFEETHATFLQTDLLKLLVKKCSKGTGFSKTWLLRDLEILSIMLYSSKKEINTLAEHGELELDERGDQEEEVERSVSSPGDQEQKKLDPLESLDEPTRICFLMAHDALNAPLHILRAIYELQMKRTDSFFLEVQKRFDGDELTTDERIRTLAQRWQPSRSLRLDEQSAKAVDTDMIILPCLSRPVRCEQATVESNPVTQKLISSTDSELQQSYAKQRRSKSAALLHKELNCKSKRAVREYLFRVNEATAVLYARHVLASLLAEWPGHVPVSEDILELSGPAHMTYILDMFMQLEDRHQWEKILQKVLQGCRESMLGTMALAACQFMEEPGMEVQVRESKHPYNNNTNFEDKVHIPGAIYLSIKFDPQCNTEEGCDELAMSSSSDFQQDRHNFSGSQQKWKDFELPGDTLYYRFTSDMSNTEWGYRFTVTAGHLGRFQTGFEILKQMLSEERVVPYLPLAKIWEWLVGVACRQTGHQRLKAIHLLLRIVRCCTHSDLCDLTLLKPLWQLFTQMEYSLFEDVTQAGILLPLHRALTELFFVTENRAQELGLLQDYLLALTTDDHLLRCAAQVMTGDALISRKDLPLTPEESHDWFESLSGFLVLNGALLLLSEVLNSVWRHCPGFTGISSVTS", "length": 3004, "header": "tr|A0AAA9TUR4-1|A0AAA9TUR4_BOVIN Isoform 1 of Zinc finger ZZ-type and EF-hand domain containing 1 OS=Bos taurus OX=9913 GN=ZZEF1 PE=4 SV=1 CANONICAL=A0AAA9TUR4-1" }, "locus": { "chromosome": "19", "start_pos": 24710635, "end_pos": 24612889, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000113705.1", "url": "https://www.ensembl.org/id/ENSBTAT00000113705.1" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000102369.1", "url": "https://www.ensembl.org/id/ENSBTAP00000102369.1" } ] } }, { "isoform_ac": "E1BNA9-1", "url": "https://www.uniprot.org/uniprotkb/E1BNA9/entry", "sequence": { "sequence": "MGNAPSHSSEDEAAAAGGEGWGPHQDWAADSGTTPGQGPAAPALPPAAALLEPARLREAAAALRPTPPCESLVSRHHGALLRWLEERLGRGEESVTLEQFGELLEARGAGFSGERFEEAFAQFDAEGDGTVDAENMLEALKNSSGANLQGELSHIIRQLQACSLVPGFIDIFSESKEGLDVHAAMILRFLHRNRLSSTVIPYPMLDHCNNMSTMRASVLRESLDQLVQKEKESPGDLTRSPEMDKLKSVAKCYAYIETSSNPADIDKMTNGETSSYWQSDGSARSHWIRLKMKPDVVLRHLSIAVAATDQSYMPQQVTVAVGRTASDLQEVRDVHIPSNVTGYVTLLENANISQLYVQINIKRCLSDGCDTRIHGLRAVGFQRVKKSGVSVSDASAIWYWSLLTSLVTASMETNPAFVQTVLRNTQKALQHMPPLSLSPGSTDFSTFLSPNVLEEVDSFLIRITSCRSTPEVELTLLAFALARGSVAKVLSSLCTVTDHLDTHYDASSLISSMASVRQNLLLKYGKPLQLTLQACDVKGKEEKSGPENLLAEPWTRDGFLTETGKTRASTIFSTGTESAFQVTQIRIMVRRGGIGAQCGLVFAYNSSSDKFHAEEHFKRFEKYDKWKLQEFRQFVKSRIGCSSDILGEDDPIGWFELEEEWDEADVKLQQCRVAKYLMVKFLCTRQESAERLGVQGLSISGYLRPARAEAEQSIVCAHCRKSTEESVCGATLLLKTLQFIQQLAHDLVQQKESGLKYKSFLDFAGLDLQIFWNFYSKLKQNPREECICAQTLLLQLLQSCFSVLQGDAPAAAEDAKAPSPRPRPVEAAKELYAHLCSVVDRLDGDSVPMEILKQEVRNTLLNGAAIFFPDRLTRRNHLFTMMKNVTEQEHKQSMQLTFRSLCTYFSDKDPGGLLLLPEKGDLADMDISEVLAVMNTLLSVAARECELLMVDGAQREVGSVLSSLFWSVQGSLLSWCYLQLKSTDSGAKDLAADLTDRYVGQFLAHVRVILESLLSQYSGKTIVEKLCNSVFSMAARQLVIFLLDFCTLDISHCTLLREFSALTELLKELCSDPEGGVNKLDVETWQQERPVVLHTWTKESAHNYENNCHEVSVFVSPGATYFEVEFDERCETEKRYDYLEFTDARGGKTRYDTKVGTDKWPKKVTFKAGPRLQFLFHSDSSNNEWGYKFTVTAYGLPDVAVSWGLDLQLLVSRLMGRLASQCMALKSVHQLGSNMAVPQAKMALVLNSPLWKPVFRHQIHPELGLEASWPTHPPQDNKEVKNIPDDHCHQFLLDFAQSDPAQNFCGPYSELFKGFIQACRKQAPKTDIVAGSTIDQAVNATFAALVYRTPDLYEKLQKYVNSGGKTALSEEFAQVYSLADGIRIWMLEMKQKSLMNLGSEAEEQRDPEAAEANPESLAKECYQKSLLLLKFLPTGGGSKESCDRSVAVDDTDHLQPLDKRQRTSSVVEEHFQASASPTEAAPPTAGDRSPGPDMQPTLPPSSGAPALEVSSVPAEEPSSPSTPTRRPPFTRGRLRLLSFRSMEEARPAPTVKEKYPVLKDLMDFIKDQSLSHESVVKVLSLRKAQAWSILEVLRIIQCCTESLGQPHCFHPPYILFLLELLTCQKEFTNYFGHLEGCGADLHKEIRDTYYQFVLFLVKAVKGFNSKNDRSLLPALSCIQTALLHLLDMGWEPSDLTFFVDIQLPDLLMKMSQENISAHDSVISQWSEEDELADAKQNSEWMDECQDGMFEAWYEKIAQEDPEKQRKMHMFIARYCDLLNVDISCDGCDEIAPWHRYRCLQCSDMDLCKTCFLGGVKPEGHGDDHEMVNMEFTCDHCQGLIIGRRMHCNVCDDFDLCYGCYAAKKYSYGHLPTHSITAHPMVTIRISDRQRLIQPYIHNYSWLLFAALALYSAHLASAEDVDGEKLDPQVRSSAATLRSRCLQLVGDCLMKAHQGKGLKALALLGVLPDGGSPPENQALPVTAPTQTSEEQPEKKAVQAAAEPAPTGPAGPRSGKRDGPKEVRPLDCKQRSKASEGVSLRKDPSCPPQISDSPADACTPTGLPDAENSEASSQKPIEEKAVIPSPEQVFAECSQKRILGLLAAMLPPLNSDPTVPLIDLEHVLPLMFQVVISNAGHLNETYHLTLGLLGQLIIRLLPAEVDAAVTKVLSAKHNLFAAGDSSVVPDGWKTTHLLFSLGAVCLDSRVGLDWACSMAEILRSLNSAPLWRDVVATFTDHCIKQLPFQLKHTNIFTLLVLVGFPQVLCVGTRCVYMDNANEPHNVIILKHFTEKNRAVIVDVKTRKRKTVKDYQLVQKGGGQEGSDSQAQLSQYSQHFAFIASHLLQTSMDSHCPEAVEATWVLSLALKGLYKTLKVHGFEETHATFLQTDLLKLLVKKCSKGTGFSKTWLLRDLEILSIMLYSSKKEINTLAEHGELELDERGDQEEEVERSVSSPGDQEQKKLDPLESLDEPTRICFLMAHDALNAPLHILRAIYELQMKRTDSFFLEVQKRFDGDELTTDERIRTLAQRWQPSRSLRLDEQSAKAVDTDMIILPCLSRPVRCEQATVESNPVTQKLISSTDSELQQSYAKQRRSKSAALLHKELNCKSKRAVREYLFRVNEATAVLYARHVLASLLAEWPGHVPVSEDILELSGPAHMTYILDMFMQLEDRHQWEKILQKVLQGCRESMLGTMALAACQFMEEPGMEVQVRESKHPYNNNTNFEDKVHIPGAIYLSIKFDPQCNTEEGCDELAMSSSSDFQQDRHNFSGSQQKWKDFELPGDTLYYRFTSDMSNTEWGYRFTVTAGHLGRFQTGFEILKQMLSEERVVPYLPLAKIWEWLVGVACRQTGHQRLKAIHLLLRIVRCCTHRKLRPSSHSDLCDLTLLKPLWQLFTQMEYSLFEDVTQAGILLPLHRALTELFFVTENRAQELGLLQDYLLALTTDDHLLRCAAQALQNIAAISLAINYPNKATRLWNVEC", "length": 2976, "header": "tr|E1BNA9-1|A0AAA9TUR4_BOVIN Computationally mapped isoform of Zinc finger ZZ-type and EF-hand domain containing 1 OS=Bos taurus OX=9913 GN=ZZEF1 PE=4 SV=4 CANONICAL=A0AAA9TUR4-1" }, "locus": { "chromosome": "19", "start_pos": 24710635, "end_pos": 24618283, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000061398.4", "url": "https://www.ensembl.org/id/ENSBTAT00000061398.4" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000053594.4", "url": "https://www.ensembl.org/id/ENSBTAP00000053594.4" } ] } } ], "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "other", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 1484, "start_aa": "Thr", "end_pos": 1484, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr1484", "evidence": [ { "id": "", "database": "GlyGen", "url": "https://data.glygen.org/" } ], "filter_code": "000000000000000010000.00000000001000.0.01000" }, { "glytoucan_ac": "", "type": "O-linked", "subtype": "other", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 2005, "start_aa": "Thr", "end_pos": 2005, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr2005", "evidence": [ { "id": "", "database": "GlyGen", "url": "https://data.glygen.org/" } ], "filter_code": "000000000000000010000.00000000001000.0.01000" }, { "glytoucan_ac": "", "type": "O-linked", "subtype": "other", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 66, "start_aa": "Thr", "end_pos": 66, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr66", "evidence": [ { "id": "", "database": "GlyGen", "url": "https://data.glygen.org/" } ], "filter_code": "000000000000000010000.00000000001000.0.01000" } ], "phosphorylation": [], "glycation": [], "keywords": [ "glycoprotein", "glycoprotein_predicted" ], "publication": [], "pathway": [], "orthologs": [], "go_annotation": { "categories": [ { "name": "Molecular Function", "total": 3, "go_terms": [ { "name": "zinc ion binding", "id": "GO:0008270", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008270", "evidence": [ { "database": "UniProtKB", "id": "A0AAA9TUR4", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TUR4" } ], "pmid": "" }, { "name": "calcium ion binding", "id": "GO:0005509", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005509", "evidence": [ { "database": "UniProtKB", "id": "A0AAA9TUR4", "url": 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"MYGPDPDLLAGESAEDETEDSIMSPIPMGPPSPFPTPKEGSPYEAPVYIPEDIRIPPGFELRESSIPGAGLGIWAKKKMEVGERFGPYMVAPRAMLNEADFGWEQMLTDAEVSSQEGCIQKISEDLDSGKLCVDAQHAGAGSWLKYIRVACSCDDQNLTMCQINEQIYYKVIKDIEPGEELLVHVKEGAYSLGAVPPSLDEEPTFRCDACDELFPSKLDLRRHKKYACSSVGAALYEGLAEELKPEGLGGGGSDGQAHECKDCERMFPTKYSLEQHMVVHTEEREYKCDQCPKAFNWKSNLIRHQMSHDSGKRFECENCVKVFTDPSNLQRHIRSQHVGARAHACPDCGKTFATSSGLKQHKHIHSTVKPFICEVCHKSYTQFSNLCRHKRMHADCRTQIKCKDCGQMFSTTSSLNKHRRFCEGKNHYPPGGIFAPGLPLTPSPLMDKAKPPPGLNHAGLGFGEYFPSRPHPGSLPFSTAPPSFPTLTPGFPGIFPPSLYPRPPLLPPTPLLKSPLNHTQDAKLPSPLGNPALPLVSAVGNSSQGTAAAAGPEEKLEGHLEEAYATKLKPRGSDLSDGSDFEDINTTTGTDLDTTTGTGSDLDSDVDSDRDKTKDKGKAAEGKPEFGGSTVPPGAPNTVGEVPVFYSQHFFPPPQEQLLTAAGAAGDSIKAIASIAEKYFGPGFMGVPEKKLGALPYHSVFPFQFLPHLPHSLYPFTDRALTHNLLVKAEPKSPRDALKASGPSAESPFDLTTKPKEAKPILLAPKVPPAPASGEEQPLDLSIGSRARASQNGGAREPRKNHVYGERRLGPSEGLPKACPAQLPQQPPLHYAKPSPFFMDPIYRVEKRKVTDPVGALKEKYLRPSPLLFHPQMSAIETMTEKLESFAAMKVDSGSSLQPLPHHPFNFRSPPPTLSDPILRKGKERYTCRYCGKIFPRSANLTRHLRTHTGEQPYRCKYCDRSFSISSNLQRHVRNIHNKEKPFKCHLCNRCFGQQTNLDRHLKKHEHEHAPVSQHAGVLTNHLGTSASSPTSESDNHALLDEKEDSYFSEIRNFIANSEMNQASTRTDKRPEVQDLDGTSQCPGLAIRKPEDVEEEEEEELEEDDDSLAGKSQDDTASPTPEPQGAYEDDEDEEPPTSLAVGFDHTRRRMQ", "length": 1151, "header": "tr|F1MTF1-1|F1MTF1_BOVIN Computationally mapped isoform of PR/SET domain 16 OS=Bos taurus OX=9913 GN=PRDM16 PE=4 SV=4 CANONICAL=A0AAA9TUY2-1" }, "locus": { "chromosome": "16", "start_pos": 49879985, "end_pos": 49578521, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000025245.7", "url": "https://www.ensembl.org/id/ENSBTAT00000025245.7" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000025245.7", "url": "https://www.ensembl.org/id/ENSBTAP00000025245.7" } ] } } ], "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "other", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 1141, "start_aa": "Thr", "end_pos": 1141, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr1141", "evidence": [ { "id": "", "database": "GlyGen", "url": "https://data.glygen.org/" } ], "filter_code": "000000000000000010000.00000000001000.0.01000" }, { "glytoucan_ac": "", "type": "O-linked", "subtype": "other", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 56, "start_aa": "Thr", "end_pos": 56, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr56", "evidence": [ { "id": "", "database": "GlyGen", "url": "https://data.glygen.org/" } ], "filter_code": "000000000000000010000.00000000001000.0.01000" } ], "phosphorylation": [], "glycation": [], "keywords": [ "glycoprotein", "glycoprotein_predicted" ], "publication": [], "pathway": [ { "id": "R-BTA-3214841", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-BTA-3214841", "resource": "Reactome", "description": "PKMTs methylate histone lysines" } ], "orthologs": [], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 3, "go_terms": [ { "name": "cytosol", "id": "GO:0005829", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005829", "evidence": [ { "database": "UniProtKB", "id": "A0AAA9TUY2", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TUY2" } ], "pmid": "" }, { "name": "nuclear body", "id": "GO:0016604", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016604", "evidence": [ { "database": "UniProtKB", "id": "A0AAA9TUY2", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TUY2" } ], "pmid": "" }, { "name": "nucleus", "id": "GO:0005634", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005634", "evidence": [ { "database": "UniProtKB", "id": "A0AAA9TUY2", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TUY2" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 6, "go_terms": [ { "name": "DNA-templated transcription", "id": "GO:0006351", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006351", "evidence": [ { "database": "UniProtKB", "id": "A0AAA9TUY2", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TUY2" } ], "pmid": "" }, { "name": "positive regulation of DNA-templated transcription", "id": "GO:0045893", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0045893", "evidence": [ { "database": "UniProtKB", "id": "A0AAA9TUY2", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TUY2" } ], "pmid": "" }, { "name": "negative regulation of transforming growth factor beta receptor signaling pathway", "id": "GO:0030512", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030512", "evidence": [ { "database": "UniProtKB", "id": "A0AAA9TUY2", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TUY2" } ], "pmid": "" }, { "name": "protein maturation", "id": "GO:0051604", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0051604", "evidence": [ { "database": "UniProtKB", "id": "A0AAA9TUY2", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TUY2" } ], "pmid": "" }, { "name": "regulation of transcription by RNA 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"https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd08391", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "530157", "url": "https://www.ncbi.nlm.nih.gov/gene/530157", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR000008", "url": "https://www.ebi.ac.uk/interpro/entry/IPR000008", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR031468", "url": "https://www.ebi.ac.uk/interpro/entry/IPR031468", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR035892", "url": "https://www.ebi.ac.uk/interpro/entry/IPR035892", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR037733", "url": "https://www.ebi.ac.uk/interpro/entry/IPR037733", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR037749", "url": "https://www.ebi.ac.uk/interpro/entry/IPR037749", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR037752", "url": "https://www.ebi.ac.uk/interpro/entry/IPR037752", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR039010", "url": "https://www.ebi.ac.uk/interpro/entry/IPR039010", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR051634", "url": "https://www.ebi.ac.uk/interpro/entry/IPR051634", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "bta:530157", "url": "https://www.genome.jp/dbget-bin/www_bget?bta:530157", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "WANKVIS", "url": "https://omabrowser.org/oma/group/WANKVIS/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "A0A3Q1MCN0", "url": "https://www.orthodb.org/?gene=A0A3Q1MCN0", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "F1MFH9", "url": "https://www.orthodb.org/?gene=F1MFH9", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR45761", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR45761", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR45761:SF4", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR45761:SF4", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00168", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00168", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF17047", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF17047", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "R-BTA-9845576", "url": "https://www.reactome.org/PathwayBrowser/#R-BTA-9845576", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "XP_002685096", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_002685096", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A3Q1MCN0", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1MCN0", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A3Q1MCN0-1", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1MCN0-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0AAA9TV05", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TV05", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0AAA9TV05-1", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TV05-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "F1MFH9", "url": "https://www.uniprot.org/uniprotkb/F1MFH9", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "F1MFH9-1", "url": "https://www.uniprot.org/uniprotkb/F1MFH9-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MPSEDPCPPGARGTERAPGREPRLPSQLLPELYAFAARVLFCLAPVYLAGYLGLSITWLLLGVLLWMWWRRNRRGKLGRLAAAFEFLDNERQFISRELLGQHLPAWIHFPDVERVEWANKIISQIWPYLSMIMENKFREKLEPKIREKSMHLRTFTFTKLYFGQKCPRVNGVKTHTDQRNRRQVVLDLQICYIGDCEINVELQKIQAGVNGIQLQGTLRIILEPLLVDKPFVGAVTMFFLQKPHLQINWTGLTNLLDAPGINEMTDSLLEDLIAAHLVLPNRVTVPVKKGLDVTNLRFPLPCGVIRVHLLEAEKLAQKDSFLGIRGKSDPYAKVNIGLQHFRSRTIYKNLSPTWNEVFEFIVYEVPGQDLEVDLYDEDPDKDDFLGSLQICLGDVMTNRVVDEWFALNNTTSGRLHLRLEWLSLITEPDAVTEDHGSFSTAILVVFLESACNLPRSPFEYLNGEYQAKKLSRFARNKVSRDPSSYVRLSVGKKTHLSKTCPCSKDPVWSQVFSFFVHNVAAEQLHLKVLDDDQECALGVLEFPLCQILPHADLTLEQRFQLDHSGLDSLISMRLVLRFLHLEERELGSPYTGPEALKKGPLFIKKVTANQDPRAPPQGEGLTDPDPASEIKQAAKNTTSATITATKPMLEETGPEPKGKDSAPMGKKSPATIYLAVPGPHSPGPIKSPRPMKCPASPFAWPPKGLAPSMSSLNSLASSCFDLTDISLNIEGGELGHRGLGEIQLTVRYVCLRRCLSVLINGCRNLTPCTSSGADPYVRVYLLPERRWASRKKTSVKRKTLEPRFDETFEFFVSMDEVQKRSLDVAVKNSRPLGSHRRKELGKVLIDLSKEDLIKGFSQWYELTPDGQPRS", "length": 870, "header": "tr|A0AAA9TV05-1|A0AAA9TV05_BOVIN Isoform 1 of Extended synaptotagmin-3 OS=Bos taurus OX=9913 GN=ESYT3 PE=3 SV=1 CANONICAL=A0AAA9TV05-1" }, "isoforms": [ { "isoform_ac": "A0A3Q1MCN0-1", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1MCN0/entry", "sequence": { "sequence": "MPSEDPCPPGARGTERAPGREPRLPSQLLPELYAFAARVLFCLAPVYLAGYLGLSITWLLLGVLLWMWWRRNRRGKLGRLAAAFEFLDNERQFISRELLGQHLPAWIHFPDVERVEWANKIISQIWPYLSMIMENKFREKLEPKIREKSMHLRTFTFTKLYFGQKCPRVNGVKTHTDQRNRRQVVLDLQICYIGDCEINVELQKIQAGVNGIQLQGTLRIILEPLLVDKPFVGAVTMFFLQKPHLQINWTGLTNLLDAPGINEMTDSLLEDLIAAHLVLPNRVTVPVKKGLDVTNLRFPLPCFIVYEVPGQDLEVDLYDEDPDKDDFLGSLQICLGDVMTNRVVDEWFALNNTTSGRLHLRLEWLSLITEPDAVTEDHGSFSTAILVVFLESACNLPRSPFEYLNGEYQAKKLSRFARNKVSRDPSSYVRLSVGKKTHLSKTCPCSKDPVWSQVFSFFVHNVAAEQLHLKVLDDDQECALGVLEFPLCQILPHADLTLEQRFQLDHSGLDSLISMRLVLRFLHLEERELGSPYTGPEALKKGPLFIKKVTANQDPRAPPQGEGLTDPDPASEIKQAAKNTTSATITATKPMLEETGPEPKGKDSAPMGKKSPATIYLAVPGPHSPGPIKSPRPMKCPASPFAWPPKGLAPSMSSLNSLASSCFDLTDISLNIEGGELGHRGLGEIQLTVRYVCLRRCLSVLINGCRNLTPCTSSGADPYVRVYLLPERRWASRKKTSVKRKTLEPRFDETFEFFVSMDEVQKRSLDVAVKNSRPLGSHRRKELGKVLIDLSKEDLIKGFSQWYELTPDGQPRS", "length": 813, "header": "tr|A0A3Q1MCN0-1|A0A3Q1MCN0_BOVIN Computationally mapped isoform of Extended synaptotagmin 3 OS=Bos taurus OX=9913 GN=ESYT3 PE=4 SV=1 CANONICAL=A0AAA9TV05-1" }, "locus": { "chromosome": "1", "start_pos": 130664098, "end_pos": 130610164, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000082902.2", "url": "https://www.ensembl.org/id/ENSBTAT00000082902.2" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000068126.1", "url": "https://www.ensembl.org/id/ENSBTAP00000068126.1" } ] } }, { "isoform_ac": "A0AAA9TV05-1", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TV05/entry", "sequence": { "sequence": "MPSEDPCPPGARGTERAPGREPRLPSQLLPELYAFAARVLFCLAPVYLAGYLGLSITWLLLGVLLWMWWRRNRRGKLGRLAAAFEFLDNERQFISRELLGQHLPAWIHFPDVERVEWANKIISQIWPYLSMIMENKFREKLEPKIREKSMHLRTFTFTKLYFGQKCPRVNGVKTHTDQRNRRQVVLDLQICYIGDCEINVELQKIQAGVNGIQLQGTLRIILEPLLVDKPFVGAVTMFFLQKPHLQINWTGLTNLLDAPGINEMTDSLLEDLIAAHLVLPNRVTVPVKKGLDVTNLRFPLPCGVIRVHLLEAEKLAQKDSFLGIRGKSDPYAKVNIGLQHFRSRTIYKNLSPTWNEVFEFIVYEVPGQDLEVDLYDEDPDKDDFLGSLQICLGDVMTNRVVDEWFALNNTTSGRLHLRLEWLSLITEPDAVTEDHGSFSTAILVVFLESACNLPRSPFEYLNGEYQAKKLSRFARNKVSRDPSSYVRLSVGKKTHLSKTCPCSKDPVWSQVFSFFVHNVAAEQLHLKVLDDDQECALGVLEFPLCQILPHADLTLEQRFQLDHSGLDSLISMRLVLRFLHLEERELGSPYTGPEALKKGPLFIKKVTANQDPRAPPQGEGLTDPDPASEIKQAAKNTTSATITATKPMLEETGPEPKGKDSAPMGKKSPATIYLAVPGPHSPGPIKSPRPMKCPASPFAWPPKGLAPSMSSLNSLASSCFDLTDISLNIEGGELGHRGLGEIQLTVRYVCLRRCLSVLINGCRNLTPCTSSGADPYVRVYLLPERRWASRKKTSVKRKTLEPRFDETFEFFVSMDEVQKRSLDVAVKNSRPLGSHRRKELGKVLIDLSKEDLIKGFSQWYELTPDGQPRS", "length": 870, "header": "tr|A0AAA9TV05-1|A0AAA9TV05_BOVIN Isoform 1 of Extended synaptotagmin-3 OS=Bos taurus OX=9913 GN=ESYT3 PE=3 SV=1 CANONICAL=A0AAA9TV05-1" }, "locus": { "chromosome": "1", "start_pos": 130664098, "end_pos": 130610164, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000099908.1", "url": "https://www.ensembl.org/id/ENSBTAT00000099908.1" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000101216.1", "url": "https://www.ensembl.org/id/ENSBTAP00000101216.1" } ] } }, { "isoform_ac": "F1MFH9-1", "url": "https://www.uniprot.org/uniprotkb/F1MFH9/entry", "sequence": { "sequence": "MPSEDPCPPGARGTERAPGREPRLPSQLLPELYAFAARVLFCLAPVYLAGYLGLSITWLLLGVLLWMWWRRNRRGKLGRLAAAFEFLDNERQFISRELLGQHLPAWIHFPDVERVEWANKIISQIWPYLSMIMENKFREKLEPKIREKSMHLRTFTFTKLYFGQKCPRVNGVKTHTDQRNRRQVVLDLQICYIGDCEINVELQKIQAGVNGIQLQGTLRIILEPLLVDKPFVGAVTMFFLQKPHLQINWTGLTNLLDAPGINEMTDSLLEDLIAAHLVLPNRVTVPVKKGLDVTNLRFPLPCGVIRVHLLEAEKLAQKDSFLGIRGKSDPYAKVNIGLQHFRSRTIYKNLSPTWNEVFEFIVYEVPGQDLEVDLYDEDPDKDDFLGSLQICLGDVMTNRVVDEWFALNNTTSGRLHLRLEWLSLITEPDAVTEDHGSFSTAILVVFLESACNLPRSPFEYLNGEYQAKKLSRFARNKVSRDPSSYVRLSVGKKTHLSKTCPCSKDPVWSQVFSFFVHNVAAEQLHLKVLDDDQECALGVLEFPLCQILPHADLTLEQRFQLDHSGLDSLISMRLVLRFLHLEERELGSPYTGPEALKKGPLFIKKVTANQDPRAPPQGEGLTDPDPASEIKQAAKNTTSATITATKPMLEETGPEPKGKDSAPMGKKSPATIYLAVPGPHSPGPIKSPRPMKCPASPFAWPPKGLAPSMSSLNSLASSCFDLTDISLNIEGGELGHRGLGEIQLTVRYVCLRRCLSVLINGCRNLTPCTSSGADPYVRVYLLPERRWASRKKTSVKRKTLEPRFDETFEFFVSMDEVQKRSLDVAVKNSRPLGSHRRKELGKVLIDLSKEDLIKGFSQWYIRAFL", "length": 865, "header": "tr|F1MFH9-1|F1MFH9_BOVIN Computationally mapped isoform of Extended synaptotagmin-3 OS=Bos taurus OX=9913 GN=ESYT3 PE=3 SV=4 CANONICAL=A0AAA9TV05-1" }, "locus": { "chromosome": "1", "start_pos": 130664098, "end_pos": 130576485, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000010667.7", "url": "https://www.ensembl.org/id/ENSBTAT00000010667.7" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000010667.7", "url": "https://www.ensembl.org/id/ENSBTAP00000010667.7" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [ { "id": "bta:530157", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?bta:530157", "resource": "KEGG Pathway" }, { "id": "R-BTA-9845576", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-BTA-9845576", "resource": "Reactome", "description": "Glycosphingolipid transport" } ], "orthologs": [ { "uniprot_canonical_ac": "A0A8V0ZF93-1", "protein_name": "Extended synaptotagmin-3", "gene_name": "ESYT3", "tax_id": 9031, "organism": "Gallus gallus", "sequence": { "sequence": "MDPAASRPAAPQRALLSSAGRALLWLGPVYLAGYLGLSGSWLLLGLALALGWARNRRGKRERLAAASVLLEDEREAVRRGLAARHLPAWVHFPDVERVEWLNKVLEQAWPYFGTIMEKTFKEVLEPKIRAKSVHLKTCTFTKIQFGEKCPRINGVKVYTKEIDRRQVILDLQICYVGDCEIHMDISKFNLGVKGVQLYGTLRVILEPLLTDAPFIGAVTLFFMQKPHLEFNWAGMSNLLDVPGINVMSDSLIQDYIAARLVLPNRITVPLKKNMSIAQLRFPVPHGVIRVHLLEAENLVQKDNFLGAIRGKSDPYALLRLGTVQYRSKTISRDLNPIWNETFEFVVHEVLGQDLEVDLYDADPDKDDFMGSLLISLLDIKNDKTVDEWFPLSKTTSGHLHLKLEWLSLVNDQEKLHEDKKGLSTAILIVYLDSAFNLPKNHFEYSNGECGARKIKNNKYLKKTEREPSSFVLLTVGSKTQKSKTCNFNKDPKWGQAFTFFVHSAHSQSLHIEIKDKDQDSSLGTSVVCLSHLLKDPNMTLDQRFQLDHSSSDSFIKIKLVLRALNVEEPDPQRVKAGVGATKKGPMHVMEKGGNQQEFVPPPKPEVSKVPPVSKDTAVQESQPKKDSSEDLDTSNSSAVPAASETVASLDETESEQDPEHRAPSALHTRAAVVPTLPVVEELRLAPSVTSLGSLPSSCFELSSSNLDLHNGMEMPLGEIQLTVRYASIRQSLVVLVNGCRNLIPSSNRGVDPYVRIYLLPDRRWISRKKTSVKKRTLNPQYDEKFEFFESLEEVKKRTLDVAVKNSRPFISQEKKELGKVWIDLSQEDLIKGFTQWYELTRSRRKKN", "length": 847 }, "evidence": [ { "id": "A0AAA9TV05", "url": "https://omabrowser.org/oma/group/A0AAA9TV05/", "database": "OMA" } ], "glygen_name": "Chicken", "common_name": "Chicken" }, { "uniprot_canonical_ac": "A0FGR9-1", "protein_name": "Extended synaptotagmin-3", "gene_name": "ESYT3", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MRAEEPCAPGAPSALGAQRTPGPELRLSSQLLPELCTFVVRVLFYLGPVYLAGYLGLSITWLLLGALLWMWWRRNRRGKLGRLAAAFEFLDNEREFISRELRGQHLPAWIHFPDVERVEWANKIISQTWPYLSMIMESKFREKLEPKIREKSIHLRTFTFTKLYFGQKCPRVNGVKAHTNTCNRRRVTVDLQICYIGDCEISVELQKIQAGVNGIQLQGTLRVILEPLLVDKPFVGAVTVFFLQKPHLQINWTGLTNLLDAPGINDVSDSLLEDLIATHLVLPNRVTVPVKKGLDLTNLRFPLPCGVIRVHLLEAEQLAQKDNFLGLRGKSDPYAKVSIGLQHFRSRTIYRNLNPTWNEVFEFMVYEVPGQDLEVDLYDEDTDRDDFLGSLQICLGDVMTNRVVDEWFVLNDTTSGRLHLRLEWLSLLTDQEVLTEDHGGLSTAILVVFLESACNLPRNPFDYLNGEYRAKKLSRFARNKVSKDPSSYVKLSVGKKTHTSKTCPHNKDPVWSQVFSFFVHNVATERLHLKVLDDDQECALGMLEVPLCQILPYADLTLEQRFQLDHSGLDSLISMRLVLRFLQVEERELGSPYTGPEALKKGPLLIKKVATNQGPKAQPQEEGPTDLPCPPDPASDTKDVSRSTTTTTSATTVATEPTSQETGPEPKGKDSAKRFCEPIGEKKSPATIFLTVPGPHSPGPIKSPRPMKCPASPFAWPPKRLAPSMSSLNSLASSCFDLADISLNIEGGDLRRRQLGEIQLTVRYVCLRRCLSVLINGCRNLTPCTSSGADPYVRVYLLPERKWACRKKTSVKRKTLEPLFDETFEFFVPMEEVKKRSLDVAVKNSRPLGSHRRKELGKVLIDLSKEDLIKGFSQWYELTPNGQPRS", "length": 886 }, "evidence": [ { "id": "A0AAA9TV05", "url": "https://omabrowser.org/oma/group/A0AAA9TV05/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "B0UYL4-1", "protein_name": "Extended synaptotagmin-3", "gene_name": "esyt3", "tax_id": 7955, "organism": "Danio rerio", "sequence": { "sequence": "MSNGVNEPPLSTEQPEGLKPKDVSQMILEFLMFMMRAIAICYPVYLTGTFGLSVSWILLSMFMWTMWKNNRRWKEQRIDTAIDFLENEKDVISTELKAMDMPPWIHFADVEKAAWINKILQQSWPFFGVYMEKLLIENIQTVVRSVHPHLKTFTFTKVHMGQKAPTITGIRAYTDELETREVILDLNIVYEADVDIDADVNRAIKVGIKGLQLQGMLRVILEPLIGQAPLVGGVTMFFIRRPALQINWTGVTNVLDGPGLSHLSESAIVDVIASLMVLPNRMCFPLIDQVKVEQMRFPLPRGVVRVHVLEARDLVAKDSHMMGLVKGKSDPYTVLRVGNKHFKTKTIKETLNPRWNEVYEFVIHEAPGQELEVELYDEDKDADDFLGRFSMDCGDVRKDREIDKWYTLEDIESGQIHFKLQWFSLCSNPELLKETSDGLACAMLALYLDCASNLPKDQREVTHNEKHGKQPKESRVTRKTNNPNSYVEFSIDLQSQKSKVVFASKDPIFDECFTFFVHSVKNQVLNVEVKEHEKKSSLGKFSLPLVRLLNVSDMTLDQRFQLERSAPNSQVKLKAVLRILTLEKQQPKVVTSAPQDKNTSTPNRPEPRTPNPTSNPVPNPAPPPAAAQLVQSNPKEKGPISSVPLSKTQVPFSVVPLNDLQAEYPPYRRSTFVGSEGLQSTPSTPGPMRRYDSHSLLSENSIASSRVDLTDSYPYPEAIMNHQGTFGQIQITLRYATLRKRLIVIVNCCNNLFSSNESGSDTYVRMYLLPDQTWKHRKRTAVKKKTVNPVFDETFEFAVSLEEARNRKLDVAVKNNKMLHKRERKEIGMVLIDMSEIDLTKGSTEWYELTLPGLKKTNWQS", "length": 861 }, "evidence": [ { "id": "A0AAA9TV05", "url": "https://omabrowser.org/oma/group/A0AAA9TV05/", "database": "OMA" } ], "glygen_name": "Zebrafish", "common_name": "Zebrafish" }, { "uniprot_canonical_ac": "D3ZC04-1", "protein_name": "Extended synaptotagmin-3", "gene_name": "Esyt3", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MQPEESCAGSAPPGPDVPERRQRSPDPEPRLSGQLLPELYSFVARVLFYLAPVYLAGYLGLSVTWLLLGALLWMWWRRNRRGKLGRLEAAFEFLEHEREFISRELRGQHLPAWIHFPDVERVEWANKIITQIWPYLSMIMENKIREKLEPKIREKSIHLRTFTFTKLYFGQKCPKVNGVKAHTDKCNRRKVTLDLQICYIGDCEISVELQKIRAGVNGVQLQGTLRVILEPLLVDKPFIGAVTVFFLQKPHLQINWTGLTNLLDMPGINELSDSLLEDLIAAHLVLPNRVTVPVKKGLDITSLRVPLPCGVIRVHLLEAKKLAQKDNFLGLGGKSDPYAKVSIGLQQCRSRTVYKNLNPTWNEVFEFMVYEVPGQDLEVDLYDEDADRDDFLGSLQISLGDVMKNRVVDEWFVLNDTTSGRLHLRLEWLSLLTDPEALENDSGLSTAILVVFLENACNLPRNPFDYLNGEYRAKKLSRFVKNKASRDPSSYVKLSVGKKTFTSKTCPHSKDPVWSQVFSFFVHSVAAEQLCLKVLDDELECALGVLEFPLCQILSCADLTLEQCFQLDHSGLDSLISMRLVLRFLRVGERELGSPYTGPDALKKGPLFVKKVDTNQGCKAPTLKEDLTDVTSILNPASYIKGASKSTDNISVATKAPEPKPEPQETGLEPKGKDGATGLCESLGRKKNPATTFLTVPGPHSPGPIKSPRPMSRPAFPFAWPLTRVAPSMSSLNSLASSCFDLTDVSFNTESGDCRLRRLGEIQLTVRYVCLRHCLRVLVNGCRNLTPCTSSGADPYVRIYLLPERRWASRKKTSVKQKTLEPLFDETFEFFVPMGEVQKRSLDVAVKNSRPLGSHRRKELGKVLIDLSKQDLIKGFSQWYELTPDGQPRS", "length": 890 }, "evidence": [ { "id": "A0AAA9TV05", "url": "https://omabrowser.org/oma/group/A0AAA9TV05/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "Q5DTI8-1", "protein_name": "Extended synaptotagmin-3", "gene_name": "Esyt3", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MQPEEPCAPSAPGGPDVPERGQRSRDPGPRLSGQLLPELYSFVARVLFYLAPVYLAGYLGLSVTWLLLGALLWMWWRRNRRGKLGRLEAAFEFLEHEREFISRELRGQHLPAWIHFPDVERVEWANKIIIQIWPYLSMIMENKIREKLEPKIREKSIHLRTFTFTKLYFGQKCPKVNGVKVHTDKRNRRKVTLDLQICYIGDCEISVELQKIRGGVSGVQLQGTLRVILEPLLVDKPFIGAVTVFFLQKPHLQINWTGLTNLLDMPGINELSDSLLEDLIAAHLVLPNRVTVPVKKGLDVTNLRVPLPCGVIRVHLLEAKKLAQKDNFLGLGGKSDPYAKVSIGLQHCRSRTIYKNLNPTWNEVFEFMVYEVPGQDLEVDLYDEDTDKDDFLGSLQICLGDVMKNRVVDEWFALNDTTSGRLHLRLEWLSLLTDQEALTENDSGLSTAILVVFLENACNLPRNPFDYLNGEYRAKKLSRFVKNKASRDPSSYVKLTVGKKTFTSKTCPHSKDPVWSQVFSFFVHSVAAEQLCLKVLDDELECALGVLEFPLCRILPCADLTLEQCFQLDHSGLDSLISMRLVLRFLRVEGRELGSPYTGPDALKKGPLFIKKVATNQGCKAPPLNEGLADVTSTSNPASYIKGASKSIDNISAATTDPEPMPEPQGPGPEPKGKDSARGLCESPGKKKNPATTFLTVPGLHSPGPIKSPRPMSRPAFPFAWPLTRVAPSMSSLNSLASSCFDLTDVSLNTEAGDSRQGRLGEIQLTVRYVCLRHCLRVLVNGCRNLTPCTSSGADPYVRIYLLPERRWASRKKTSVKQKTLEPLFDETFEFFVPMGEVQKRSLDVAVKNSRPLGSHRRKELGKVLIDLSKQDLIKGFSQWYELTADGQPRS", "length": 891 }, "evidence": [ { "id": "A0AAA9TV05", "url": "https://omabrowser.org/oma/group/A0AAA9TV05/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" } ], "go_annotation": { "categories": [ { "name": "Biological Process", "total": 2, "go_terms": [ { "name": "lipid transport", "id": "GO:0006869", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006869", "evidence": [ { "database": "UniProtKB", "id": "A0AAA9TV05", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TV05" } ], "pmid": "" }, { "name": "endoplasmic reticulum-plasma membrane tethering", "id": "GO:0061817", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0061817", "evidence": [ { "database": "UniProtKB", "id": "A0AAA9TV05", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TV05" } ], "pmid": "" } ] }, { "name": "Molecular Function", "total": 7, "go_terms": [ { "name": "metal ion binding", "id": "GO:0046872", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0046872", "evidence": [ { "database": "UniProtKB", "id": "A0AAA9TV05", "url": 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"MNRAKPTTVRRPSAAAKPSGHPPPGDFIALGSKGQTTESKTASTLLKPAPSGLPSERKRDAAAALAGASALPGLTKRPKLSSTPPLSALGRLAEAAVAEKRAISPSIKEPSVVPIEVPPTVLLDEIEAAELEGNDDRLEGVLCGAVKQLKVTRAKPDSVLYLSLMYLAKMKPNIFATEGVIEALCSLLRRDASVSFKAKGNSLVSVLACNLLMAAYEEDENWPEIFVKVYIEDSLGERIWVDSPHCRTFVDNIQTAFNTKMPPKSVLLQGEAGRGGGDLSAGSSPHPSLTEEEDSQTELLIAEEKLSPEQEGQLMPRYEELAESVEEYVLDMLRDQLNRRQPIDSVSRNLLRLLTSACGYKEARLMAVQRLEMWLQNPKLTRPAQDLLMSVCMNCSTHGAEDMDVISHLIKIRLKPKVLLNHYMLCIRELLNAHKDNLGTTIKFVIFNELSNARNPNNMQILYTVLQHSSELAPKFLAMVFQDLLTNKDDYLRASRALLREIIKQTKHEINFQAFCLGLMQERKEPQYLDMEFKERFVVHVTDVLAVSMMLGITAQVKEAGVAWDKGEKKNLEVLRSFQNQIAAIQRDAVWWLHTVVPSISKLAPKDYVHCLHKVLFTEQPETYYKWDNWPPESDRNFFLRLCSEVPILEDTLMRILVIGLSRELPLGPADAMELADHLVKRAAAVQADDVDVLKVERVQLIDAVLNLCTYHHPENIQLPPGYQPPNLAISTLYWKAWPLLLVVAAFNPENIGLAAWEEYPTLKMLMEMAMTNNYSYPPCTLTDEESRTEMINRELQVSQREKQEILAFEGHLAAASTRQTITESSSLLLSQLTSLEPQGPPRRPPPHILDQVKGLNQSLRLGHLLCRSRNPDFLLNIIQRQASSQSMPWLADLVQSSEGSLDVLPVQCLCEFLLHDAADEPASGGEEEEGESKEQKARKRQRQQKQKQLLGRLQDLLLGPKADEQTTCEVLDYFLRRLGSSQVAARVLAMKGLSLVLSEGSLRDGEEKEPPLEEDSGDADALQGYQWLLRDLPRLPLFESVRSTTALALQQAIHMETDPQTISAYLVYLSQHTPVEEQGQHSDLALDVARLIVERSTIMSHLFSKRSCSAESDVVLAALLSIFSRYVQRMRKSKEGEEVYSWSESQDQVFLRWSSGETATMHILVVHAMVILLTLGPPRAGDSEFQALLDIWFPEKKPLPTAFLVDTSEEALLLPDWLKLRMIRSEVPRLVDAALQDLEPQQLLLFVQSFGIPVSSMSKLLQYLDQAVAHDPQTLEQNIMDKNYMAHLVEVQHERGASGGQTFHSLLTASLPARRDSTEAPKPKSSPEQPPGQGGTRAVARVRALGPEDDLAGLLLQIFPLSPGPRWKSSHARPAALALQQALGRELARVRQGSPEVPGVAVRLLQALATLLSSPHGGALALAMHRSHVLACPLMRQLCQYQRCAPQDTGFSSLFLKVLVQALQWLDGPSVEAGPLQAQLRLFAAQCSARRRISNVRSGFLHLVEALTFRGDPEAVSSTVRAIVATLRSGEQCDVEPELISKVLRSLIEVRSPHLEELLAALFSTASAVPPSGPVVVVSSLLLPEKEEPLAPGKQEADSCSQEAMLLGPCSGLLVDWLEMLDPEVVGSCPDLQQRLLFSRGKGKGHPGPQVPSFRPYLLALLTHQSSWSTLHQCIRILLGRGREQRFDPSASLDFLWACIHVPRIWQGRDQRTPQKRREELVLRVQPAELVGLVELILAEAEARSQDGDAGACGLLQARLPLLLSCCRGGDEGIKKVTAHLTSCVQQWGDSVLGKCSRDLLVQLYLQRPDLRVPLPDVLLHSQGATGSSVCKLDGLIHRFITLLADTSDSRASESRVADASMACRKLAVAHPLLLLRHLPMIAALLHGRTHLNFQEFRQQNHLTFFMHVLGVLELLQPQVFQSEHQGALWDCLLSFVRLLRNYRKSSRHLVPFASKFVRFTHKYISCSPAAAVAFLQKHLNVLHDLSLDSSDLVMLKSLLAGLSLPSRDGGADRALDEEGEDESSAGSLPLVSVCIFTPLTAAEMAPYMKRLSRGQTVEDLLEVLSDVDEMSRRRPEILGFFSTSLQRLMSSAEESCRSLAFSLALRSIQNNPGIAADFLPTFMYCLGSRDFEVVQTALRNLPEYTLLCQEHAAVLLHRAFLVGMYGQMDTSAQISEALRILHLEAMM", "length": 2189, "header": "tr|A0AAA9TV32-1|A0AAA9TV32_BOVIN Isoform 1 of Integrator complex subunit 1 OS=Bos taurus OX=9913 GN=INTS1 PE=4 SV=1 CANONICAL=A0AAA9TV32-1" }, "isoforms": [ { "isoform_ac": "A0AAA9TV32-1", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TV32/entry", "sequence": { "sequence": "MNRAKPTTVRRPSAAAKPSGHPPPGDFIALGSKGQTTESKTASTLLKPAPSGLPSERKRDAAAALAGASALPGLTKRPKLSSTPPLSALGRLAEAAVAEKRAISPSIKEPSVVPIEVPPTVLLDEIEAAELEGNDDRLEGVLCGAVKQLKVTRAKPDSVLYLSLMYLAKMKPNIFATEGVIEALCSLLRRDASVSFKAKGNSLVSVLACNLLMAAYEEDENWPEIFVKVYIEDSLGERIWVDSPHCRTFVDNIQTAFNTKMPPKSVLLQGEAGRGGGDLSAGSSPHPSLTEEEDSQTELLIAEEKLSPEQEGQLMPRYEELAESVEEYVLDMLRDQLNRRQPIDSVSRNLLRLLTSACGYKEARLMAVQRLEMWLQNPKLTRPAQDLLMSVCMNCSTHGAEDMDVISHLIKIRLKPKVLLNHYMLCIRELLNAHKDNLGTTIKFVIFNELSNARNPNNMQILYTVLQHSSELAPKFLAMVFQDLLTNKDDYLRASRALLREIIKQTKHEINFQAFCLGLMQERKEPQYLDMEFKERFVVHVTDVLAVSMMLGITAQVKEAGVAWDKGEKKNLEVLRSFQNQIAAIQRDAVWWLHTVVPSISKLAPKDYVHCLHKVLFTEQPETYYKWDNWPPESDRNFFLRLCSEVPILEDTLMRILVIGLSRELPLGPADAMELADHLVKRAAAVQADDVDVLKVERVQLIDAVLNLCTYHHPENIQLPPGYQPPNLAISTLYWKAWPLLLVVAAFNPENIGLAAWEEYPTLKMLMEMAMTNNYSYPPCTLTDEESRTEMINRELQVSQREKQEILAFEGHLAAASTRQTITESSSLLLSQLTSLEPQGPPRRPPPHILDQVKGLNQSLRLGHLLCRSRNPDFLLNIIQRQASSQSMPWLADLVQSSEGSLDVLPVQCLCEFLLHDAADEPASGGEEEEGESKEQKARKRQRQQKQKQLLGRLQDLLLGPKADEQTTCEVLDYFLRRLGSSQVAARVLAMKGLSLVLSEGSLRDGEEKEPPLEEDSGDADALQGYQWLLRDLPRLPLFESVRSTTALALQQAIHMETDPQTISAYLVYLSQHTPVEEQGQHSDLALDVARLIVERSTIMSHLFSKRSCSAESDVVLAALLSIFSRYVQRMRKSKEGEEVYSWSESQDQVFLRWSSGETATMHILVVHAMVILLTLGPPRAGDSEFQALLDIWFPEKKPLPTAFLVDTSEEALLLPDWLKLRMIRSEVPRLVDAALQDLEPQQLLLFVQSFGIPVSSMSKLLQYLDQAVAHDPQTLEQNIMDKNYMAHLVEVQHERGASGGQTFHSLLTASLPARRDSTEAPKPKSSPEQPPGQGGTRAVARVRALGPEDDLAGLLLQIFPLSPGPRWKSSHARPAALALQQALGRELARVRQGSPEVPGVAVRLLQALATLLSSPHGGALALAMHRSHVLACPLMRQLCQYQRCAPQDTGFSSLFLKVLVQALQWLDGPSVEAGPLQAQLRLFAAQCSARRRISNVRSGFLHLVEALTFRGDPEAVSSTVRAIVATLRSGEQCDVEPELISKVLRSLIEVRSPHLEELLAALFSTASAVPPSGPVVVVSSLLLPEKEEPLAPGKQEADSCSQEAMLLGPCSGLLVDWLEMLDPEVVGSCPDLQQRLLFSRGKGKGHPGPQVPSFRPYLLALLTHQSSWSTLHQCIRILLGRGREQRFDPSASLDFLWACIHVPRIWQGRDQRTPQKRREELVLRVQPAELVGLVELILAEAEARSQDGDAGACGLLQARLPLLLSCCRGGDEGIKKVTAHLTSCVQQWGDSVLGKCSRDLLVQLYLQRPDLRVPLPDVLLHSQGATGSSVCKLDGLIHRFITLLADTSDSRASESRVADASMACRKLAVAHPLLLLRHLPMIAALLHGRTHLNFQEFRQQNHLTFFMHVLGVLELLQPQVFQSEHQGALWDCLLSFVRLLRNYRKSSRHLVPFASKFVRFTHKYISCSPAAAVAFLQKHLNVLHDLSLDSSDLVMLKSLLAGLSLPSRDGGADRALDEEGEDESSAGSLPLVSVCIFTPLTAAEMAPYMKRLSRGQTVEDLLEVLSDVDEMSRRRPEILGFFSTSLQRLMSSAEESCRSLAFSLALRSIQNNPGIAADFLPTFMYCLGSRDFEVVQTALRNLPEYTLLCQEHAAVLLHRAFLVGMYGQMDTSAQISEALRILHLEAMM", "length": 2189, "header": "tr|A0AAA9TV32-1|A0AAA9TV32_BOVIN Isoform 1 of Integrator complex subunit 1 OS=Bos taurus OX=9913 GN=INTS1 PE=4 SV=1 CANONICAL=A0AAA9TV32-1" }, "locus": { "chromosome": "25", "start_pos": 41453081, "end_pos": 41429465, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000123934.2", "url": "https://www.ensembl.org/id/ENSBTAT00000123934.2" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000100444.1", "url": "https://www.ensembl.org/id/ENSBTAP00000100444.1" } ] } }, { "isoform_ac": "E1B8S1-1", "url": "https://www.uniprot.org/uniprotkb/E1B8S1/entry", "sequence": { "sequence": "MNRAKPTTVRRPSAAAKPSGHPPPGDFIALGSKGQTTESKTASTLLKPAPSGLPSERKRDAAAALAGASALPGLTKRPKLSSTPPLSALGRLAEAAVAEKRAISPSIKEPSVVPIEVPPTVLLDEIEAAELEGNDDRLEGVLCGAVKQLKVTRAKPDSVLYLSLMYLAKMKPNIFATEGVIEALCSLLRRDASVSFKAKGNSLVSVLACNLLMAAYEEDENWPEIFVKVYIEDSLGERIWVDSPHCRTFVDNIQTAFNTKMPPKSVLLQGEAGRGGGDLSAGSSPHPSLTEEEDSQTELLIAEEKLSPEQEGQLMPRYEELAESVEEYVLDMLRDQLNRRQPIDSVSRNLLRLLTSACGYKEARLMAVQRLEMWLQNPKLTRPAQDLLMSVCMNCSTHGAEDMDVISHLIKIRLKPKVLLNHYMLCIRELLNAHKDNLGTTIKFVIFNELSNARNPNNMQILYTVLQHSSELAPKFLAMVFQDLLTNKDDYLRASRALLREIIKQTKHEINFQAFCLGLMQERKEPQYLDMEFKERFVVHVTDVLAVSMMLGITAQVKEAGVAWDKGEKKNLEVLRSFQNQIAAIQRDAVWWLHTVVPSISKLAPKDYVHCLHKVLFTEQPETYYKWDNWPPESDRNFFLRLCSEVPILEDTLMRILVIGLSRELPLGPADAMELADHLVKRAAAVQADDVDVLKVERVQLIDAVLNLCTYHHPENIQLPPGYQPPNLAISTLYWKAWPLLLVVAAFNPENIGLAAWEEYPTLKMLMEMAMTNNYSYPPCTLTDEESRTEMINRELQVSQREKQEILAFEGHLAAASTRQTITESSSLLLSQLTSLEPQGPPRRPPPHILDQVKGLNQSLRLGHLLCRSRNPDFLLNIIQRQASSQSMPWLADLVQSSEGSLDVLPVQCLCEFLLHDAADEPASGGEEEEGESKEQKARKRQRQQKQKQLLGRLQDLLLGPKADEQTTCEVLDYFLRRLGSSQVAARVLAMKGLSLVLSEGSLRDGEEKEPPLEEDSGDADALQGYQWLLRDLPRLPLFESVRSTTALALQQAIHMETDPQTISAYLVYLSQHTPVEEQGQHSDLALDVARLIVERSTIMSHLFSKRSCSAESDVVLAALLSIFSRYVQRMRKSKEGEEVYSWSESQDQVFLRWSSGETATMHILVVHAMVILLTLGPPRAGDSEFQALLDIWFPEKKPLPTAFLVDTSEEALLLPDWLKLRMIRSEVPRLVDAALQDLEPQQLLLFVQSFGIPVSSMSKLLQYLDQAVAHDPQTLEQNIMDKNSTEAPKPKSSPEQPPGQGGTRAVARVRALGPEDDLAGLLLQIFPLSPGPRWKSSHARPAALALQQALGRELARVRQGSPEVPGVAVRLLQALATLLSSPHGGALALAMHRSHVLACPLMRQLCQYQRCAPQDTGFSSLFLKVLVQALQWLDGPSVEAGPLQAQLRLFAAQCSARRRISNVRSGFLHLVEALTFRGDPEAVSSTVRAIVATLRSGEQCDVEPELISKVLRSLIEVRSPHLEELLAALFSTASAVPPSGPVVVVSSLLLPEKEEPLAPGKQEADSCSQEAMLLGPCSGLLVDWLEMLDPEVVGSCPDLQQRLLFSRGKGKGHPGPQVPSFRPYLLALLTHQSSWSTLHQCIRILLGRGREQRFDPSASLDFLWACIHVPRIWQGRDQRTPQKRREELVLRVQPAELVGLVELILAEAEARSQDGDAGACGLLQARLPLLLSCCRGGDEGIKKVTAHLTSCVQQWGDSVLGKCSRDLLVQLYLQRPDLRVPLPDVLLHSQGATGSSVCKLDGLIHRFITLLADTSDSRASESRVADASMACRKLAVAHPLLLLRHLPMIAALLHGRTHLNFQEFRQQNHLTFFMHVLGVLELLQPQVFQSEHQGALWDCLLSFVRLLRNYRKSSRHLVPFASKFVRFTHKYISCSPAAAVAFLQKHLNVLHDLSLDSSDLVMLKSLLAGLSLPSRDGGADRALDEEGEDESSAGSLPLVSVCIFTPLTAAEMAPYMKRLSRGQTVEDLLEVLSDVDEMSRRRPEILGFFSTSLQRLMSSAEESCRSLAFSLALRSIQNNPGIAADFLPTFMYCLGSRDFEVVQTALRNLPEYTLLCQEHAAVLLHRAFLVGMYGQMDTSAQISEALRILHLEAMM", "length": 2156, "header": "tr|E1B8S1-1|E1B8S1_BOVIN Computationally mapped isoform of Integrator complex subunit 1 OS=Bos taurus OX=9913 GN=INTS1 PE=4 SV=4 CANONICAL=A0AAA9TV32-1" }, "locus": { "chromosome": "25", "start_pos": 41453081, "end_pos": 41429465, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000000845.8", "url": "https://www.ensembl.org/id/ENSBTAT00000000845.8" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000000845.7", "url": "https://www.ensembl.org/id/ENSBTAP00000000845.7" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [ { "id": "bta:790146", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?bta:790146", "resource": "KEGG Pathway" }, { "id": "R-BTA-6807505", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-BTA-6807505", "resource": "Reactome", "description": "RNA polymerase II transcribes snRNA genes" } ], "orthologs": [ { "uniprot_canonical_ac": "A0A8V0Z496-1", "protein_name": "Integrator complex subunit 1", "gene_name": "INTS1", "tax_id": 9031, "organism": "Gallus gallus", "sequence": { "sequence": "MNRPKAAAVRRPSAAPKPSAHPPPGDFIALGSKGQGGDGKAAVTLLKPAPAGLPSERKRDAAAALSGPAGLGGLSKRPKLSATPPLSALGRLAEAAVAEKRAISPSIKEPSVIPIEVVPTVLLDEIEAAEAEGNDDRIEGVLCGAAKQLKMNRAKPDTTLYLSLMYLAKIKPNIFATEGVIEALCSLLRRDASINFKAKGNSLVSVLACNLLMAAYEEDENWPEIFVKVYIEDSLGERIWVDSPHCKTFVDNIQTAFNTKMPPKSMLLHGEVGRSGGDISAGSSPHPSMTEEEDSQSELLIAEEKMSPEQEGQLMPRYDDLAESVEEYVLDMLRDQLNRRQPMDNVSRNLLRLLTATCGYKEVRQMAVQRLEMWLQNPKLTKPAQDLLMSVCMNCNTHSSEDMEVISNLIKIRLKPKVLLNHYMLCVRELLNAHRDNLGTTIKFVIFNELSNARNPNNMQILYTVLQHSSEQAPKYLAMVFQDLLTTKDDYLRASRALLREIIKQTKHEINFQAFCLGLMQERKEAQYAEMEFKERFVIHITDLLAVSMMLGITAQVKEAGIAWDKGEKKNLEVLRSFQNQIAAIQRDAVWWLHTVVPSISKLAPKDYVHCLHKVLFTEQPETYYKWDNWPPESDRNFFLRLCSEVPILEDTLMRILVIGLSRDLPLGPADAMELADHLVKRAAAVQADDVEVLRVERIQLIDAVLNLCTYHHPENIQLPPGYQPPNLAISTLYWKAWPLLLVVAAFNPENIGLAAWEEYPSLKMLMEMVMTNNYSYPQCTLTDEETRTEMINRELQISQREKQEILAFEGHLAAASTKQTITESSSLLLSQLTSLDPQGPPRRPPPHVLEQVKSLNQSLRLGHLLCRSRHPDFLLNIIQRQASSQSMPWLADLVQSSEGSLDVLPVQCLCEFLLHDAADESTSGEEEEEGESKEQRAKKRQRQQKQRQLLGRLQDLLLGPKADEQTTCEVLDYFLRRLSSSQVASRVLAMKGLSLVLSEGGLRDGEEKDHPMEEDSGDSELLQGYQWLLRDLPRLPLFDSVRATTAVALQQAIHMETDPQTISAYLVYLSQHAPVEEQGQHNDLALDVARLIVERSTIMSHLFSKLSYCAESDAVLVALLSIFSRYIKCMRQSKEGEEVYRWSESQDQVFLRWTSGETATMHILVVHAMVILLTLGPPQAGDGDFYTLLDIWFPEKKPLPTAFLVDTSEEALLLPDWLKLRMIRSEVPRLVDAALQDLEPQQLLLFVQSFGIPVSSMSKLLQYLDQAVSHDPQTLEQNIMDKNYMAHLVEVQHERGATGGQTFHSLLTASLPARRDSAETAKSKSSPESNQGQSRIRALSQVRVLGPEDDLAGIFLQLFPLNPDPRWQNSNLRPLALALQQALGQELAHIRQGNTQVTGITAQLLQAVAALMNSPHSGALVMAMHRHHFISCPLMRQLYQYQRCMPQDTAFSSLFFKVLMQMLQWLDNPAVEDGPLRAQLKGFAVQYSSRHRISDVRGGFLHLTEALTFRHDPDLISSTVRAIIATLKSGEKGNVEPELISKVLQGLIETQSPYLEELLTVLFSATVETTARFPAMKPIAVVSSLLLQDKEETTVKKEVDSCSTEAAWLGPSSGLLNDWLEMLDPEVISSCPDLQQKLLFSWNKAGSQVPSFRPYLLALLTHQSSWTTLHQCIKLLLCRNREQRFDPTASLDFLWACIHIPRIWQGRDQRTPQKRREEFVLHLKASELISMVELILAEAETRYQNTEEASCTLIQSRLPLLLSCSHGDLESMKKVTEYLTSCIQQWGSSSVGKCCQDLLLQIYLQLPEQLVPLPEMLLTSEGARDSSTCKLDALVHRFINLLADTSDSKSSESRVWDANMACRKLAVAHPILLLRHLPMIAALLHGRVHLNFQEFRQQNHLTFFIHVLGILELLQPQVFQNEHQAALWDCLLSFIRLLLNYRKSSRHLAAFISKYVQFIQKYITCNAQAAVSFLQKHSDPLHDLSSDNSDLAMLKSLLAGLSLPSKSSILDRGSEEEKDDEAAAGSLPLVSVSLFTPLTPAEMAPYMKRLSRGQTVEDILEVLTDIDEMSRRRPEILSFFATNLQKLMSSSEESCRNLAFSLALRSIQNNPSIAADFLPTFMYCLGSRDFEVVQTALRNLPEYTLLCQEHAAVLLHRAFLVGMYSQIDTSSQISEALKVLHMEATI", "length": 2187 }, "evidence": [ { "id": "A0AAA9TV32", "url": "https://omabrowser.org/oma/group/A0AAA9TV32/", "database": "OMA" } ], "glygen_name": "Chicken", "common_name": "Chicken" }, { "uniprot_canonical_ac": "A0A9J7FYY8-1", "protein_name": "Integrator complex subunit 1 isoform X1", "gene_name": "Ints1", "tax_id": 10029, "organism": "Cricetulus griseus", "sequence": { "sequence": "MTERASDSRRLLPGEGASARGARAAGRMNRAKPTTVRRPSAAAKPSGHPPPGDFIALGSKGQANESKTASTLLKPAPSGLPSERKRDATASLSGTSALTGLTKRPKLSSTPPLSALGRLAEAAVAEKRAISPSIKEPSVVPIEVLPTVLLDEIEAAELEGNDDRIEGVLCGAVKQLKVTRAKPDSTLYLSLMYLAKIKPNIFATEGVIEALCSLLRRDASVNFKAKGNSLVSVLACNLLMAAYEEDENWPEIFVKVYIEDSLGERIWVDSPHCRTFVDNIQTAFNTKMPPKSVLLQGEGARSGGELGAGSSPHPSLTEEEDSQTELLIAEEKLSPEQEGQLMPRPRYDELTESVEEYVLDMLRDQLNRRQPIDNVSRNLLRLLTATCGYKEVRLLAVQRLEMWLQNPKLTRPAQDLLMSVCMNCNSHGPEDMDAISHLIKIRLKPKVLLNHYMLCIRELLNAHKDNLGTTIKFVIFNELSNARNPNNMQILYTVLQHSSELAPKFLAMVFQDLLTNKDDYLRASRALLREIIKQTKHEINFQAFCLGLMQERKEPQYLEMEFKERFVVHITDVLAVSMMLGITAQVKEAGVAWDKGEKRNLEVLRTFQNQIAAIQRDAVWWLHTVVPSISKLAPKDYVHCLHKVLFTEQPETYYKWDNWPPESDRNFFLRLCSEVPILEDTLMRILVIGLSRELPLGPADAMELADHLVKRAAAVQADDVEVLKVERIQLIDAVLNLCTYHHPENIQLPPGYQPPNLAISTLYWKAWPLLLVVAAFNPENIGLAAWEEYPTLKMLMEMVMTNNYSYPPCTLTDEETRTEMINRELQISQREKQEILAFEGHLAAASTKQTITESSSLLLSQLTSLDPQGPPRRPPPHILDQVKALNQSLRLGHLLCRSRNPDFLLHIIQRQASSQSMPWLADLVQSSEGSLDVLPVQCLCEFLLHDAADATASGEEDEEGESREQKAKKRQRQQKQRQLLGRLQDLLLGPKADEQTTCEVLDYFLRRLGSSQVASRVLAMKGLSLVLSEGGLRDKEEKEPPMEEDVGEADALQGYQWLLRDLPRLPLFDSVRTTTALALQQAIHMETDPQTISAYLIYLSQHTPVEEQGPHSDLALDVARLVVERSTIMAHLFSKPSCSTASDAVLSALLSVFSRYVRRMRKSKEGEEVYSWSESQDQVFLRWTSGETATMHILVVHAMVILLTLGPPRAGDGEFHELLDIWFPEKKPLPTAFLVDTSEEALLLPDWLKLRMIRSEVPRLVDAALQDLEPQQLLLFVQSFGIPVSSMSKLLQYLDQAVAQDPQTLEQNIMDKNYMAHLVEVQHERGASGGQTFHSLLTASLPPRRDSTEAPKPESSPEPPPGQGRTRAGTQVPVLGPEDDLAGIFLQIFPLSPDPRWQSSSPRPLALALQQALGQELARVRQGNPEVPGITVRLLQAMATLLSSPHGGTLALAMHHSHFLSCPLMRQLYQYQRAVPQDTGFSSLFLKVLMQILQWLDSPAVEDGPLQAQLKLFATRYSARRRISDVRSGLLHLAEALSFHHDLEVANSTVRAVIATLKSGEKCTVEPELISKVLRGLIEVRSPHLEELLTALFSATAEASCPSSASGPIVVVSSLLLQEKDEPLGPSKQDAEGASTETMRLGPASGLLVDWLETLDPEVVSSCPDLQRRLLFSRRKGKGHISAQVLSFRPYLLALLTHQASWSTLHRCIRILLGKSREQRLDPSASLDFLWACIHVPRIWQGRDQRTPQKRREELVLHVQGPELLSLVELILSEAETRSQDGDSAARTLIQTRLPLLLSCCRGNNESVGKVTEHLTSCIQQWGDSVLGQRCRDLLLQLYLQRPEVRVPVPEVLLQSEGATSSSICKLDGLIHRFITLLADTSDSRSSESRVADANMACRKLAVAHPILLLRHLPMIAALLHGRTHLNFQEFRQQNHLAFFLHVLGILELLQPRVFQSEHQGALWDCLRSFIRLLLNYRKSSRHLAPFISKFVQFIHKYVACSAPAAVTFLQKHAEPLHDLSFDNSDLVMLKSLLAGLSLPSRDGRTDQGLDEEGEDERSAGSLPLVSVSLSTPLTVADVAPHMKRLSRGQAVEDVLETLSDIDEMSRRRPEVLGFFSTNLQRLMSSAEESCRNLAFSLALRSIQNNPSIAADFLPTFMYCLGSRDFEVVQTALRNLPEYTLLCQEHAAVLLHRAFLVGMYGQIDTSAQISEALKILHMEAVM", "length": 2222 }, "evidence": [ { "id": "A0AAA9TV32", "url": "https://omabrowser.org/oma/group/A0AAA9TV32/", "database": "OMA" } ], "glygen_name": "Hamster", "common_name": "Chinese hamster" }, { "uniprot_canonical_ac": "F1M8D7-1", "protein_name": "Integrator complex subunit 1", "gene_name": "Ints1", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MTERASDSRRLLPGDGASSRGARAAGRMNRAKPTTVRRPSAAAKPSGHPPPGDFIALGSKGQANESKTASTLLKPAPSGLPSERKRDASASLSGASGLTGLTKRPKLSSTPPLSALGRLAEAAVAEKRAISPSIKEPSVVPIEVLPTVLLDEIEAAELEGNDDRIEGVLCGAVKQLKVTRAKPDSTLYLSLMYLAKIKPNIFATEGVIEALCSLLRRDASVNFKAKGNSLVSVLACNLLMAAYEEDENWPEIFVKVYIEDSLGERIWVDSPHCRTFVDNIQTAFNTKMPPKSVLLQGEGARSGGELGAGSSPHPSLTEEEDSQTELLIAEEKLSPEQEGQLMPRPRYDELTESVEEYVLDMLRDQLNRRQPIDNVSRNLLRLLTATCGYKEVRLLAVQRLEMWLQNPKLTRPAQDLLMSVCMNCNSHGSEDMDVISHLIKIRLKPKVLLNHYMLCIRELLNAHKDNLGTTIKFVIFNELSNARNPNNMQILYTVLQHSSELAPKFLAMVFQDLLTNKDDYLRASRALLREIIKQTKHEINFQAFCLGLMQERKEPQYLEMEFKERFVVHITDVLAVSMMLGITAQVKEAGVAWDKGEKRNLEVLRTFQNQIAAIQRDAVWWLHTVVPSISKLAPKDYVHCLHKVLFTEQPETYYKWDNWPPESDRNFFLRLCSEVPILEDTLMRILVIGLSRELPLGPADAMELADHLVKRAAAVQADDVEVLKVERIQLIDAVLNLCTYHHPENIQLPPGYQPPNLAISTLYWKAWPLLLVVAAFNPENIGLAAWEEYPTLKMLMEMVMTNNYSYPPCTLTDEETRTEMINRELQISQREKQEILAFEGHLAAASTKQTITESSSLLLSQLTSLDPQGPPRRPPPHILDQVKALNQSLRLGHLLCRSRNPDFLLHIIQRQASSQSMPWLADLVQSSEGSLDVLPVQCLCEFLLHDAADATASGEEDDEGESREQKAKKRQRQQKQRQLLGRLQDLLLGPKADEQTTCEVLDYFLRRLGSSQVASRVLAMKGLSLVLSEGGLRDKEEKEPPMEEDVGEADALQGYQWLLRDLPRLPLFDSVRTTTALALQQAIHMETDPQTISAYLIYLSQHTPVEEQGPHSDLALDVARLVVERSTIMAHLFSKPSCSTASDAVLSALLSVFSRYVRRMRKSKEGEEVYSWSESQDQVFLRWTSGETATMHILVVHAMVILLTLGPPRSGDSEFSELLDIWFPEKKPLPTAFLVDTSEEALLLPDWLKLRMIRSEVPRLVDAALQDLEPQQLLLFVQSFGIPVSSMSKLLQYLDQAVAQDPQTLEQNIMDKNYMAHLVEVQHERGASGGQTFHSLLTASLPPRRDSTEAPKPESSPEPPPGQGRTRAGTQVPVLGPEDDLAGIFLQIFPLSPDPRWQSSSPRPLALALQQALGQELARVRQGNPEVPGITVRLLQAMATLLSSPHGGTLALAMHHSHFLSCPLMRQLCQYQRAVPQDTGFSSLFLKVLMQILQWLDSPAVEDGPLQAQLKLFATRYSARRRISDVRSGLLHLAEALSFHRDLEVANSTARAVIATLRSGEKCTVEPELISKVLRGLIEVRSPHFEELLTALFSATAETCPSPASGPIVVVSSLLLQERDEPLGPSTQDAEGASTEAMRLGPASGLLVDWLETLDPEVVCSCPDLQWKLLFSRRKGKGHISAQVLSFRPYLLALLTHQASWSTLHRCTRVLLSKSREQRLDPSASLDFLWACIHVPRIWQGRDQRTPQKRREELVLHVQGPELLSLVELILSEAETRSQDGDSAARTLIQTRLPLLLSCCRSNDESIGKVTEHLTSCIQQWGDSVLGQRCRDLLLQLYLQRPEVRVPVPEVLLQSEGATSSSICKLDGLIHRFITLLADTSDSRSSESRVADANMACRKLAVAHPILLLRHLPMIAALLHGRTHLNFQEFRQQNHLAFYLHVLGILELLQPRVFQSEHQGALWDCLRSFIRLLLNYRKSSRQLAPFISKFVQFIHKYVACSAPAAVAFLQKHAEPLHDLSFDNSDLVMLKSLLAGLSLPSRDGRADQGLDEEGEDERSAGSLPLVSVSLSTPLTVADVAPHMKRLSRGQAVEDVLETLSDIDEMSRRRPEVLGFFSTNLQRLMSSAEESCRNLAFSLALRSIQNNPSIAADFLPTFMYCLGSRDFEVVQTALRNLPEYTLLCQEHAAVLLHRAFLVGMYGQIDTSAQISEALKILHMEAVM", "length": 2221 }, "evidence": [ { "id": "A0AAA9TV32", "url": "https://omabrowser.org/oma/group/A0AAA9TV32/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "Q6P4S8-1", "protein_name": "Integrator complex subunit 1", "gene_name": "Ints1", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MNRAKPTTVRRPSAAAKPSGHPPPGDFIALGSKGQASESKTTSTLLKPAPSGLPSERKRDASASLSGTSALTGLTKRPKLSSTPPLSALGRLAEAAVAEKRAISPSIKEPSVVPIEVLPTVLLDEIEAAELEGNDDRIEGVLCGAVKQLKVTRAKPDSTLYLSLMYLAKIKPNIFATEGVIEALCSLLRRDASVNFKAKGNSLVSVLACNLLMAAYEEDENWPEIFVKVYIEDSLGERIWVDSPHCRTFVDNIQTAFNTKMPPKSVLLQGEGARSGGELGAGSSPHPSLTEEEDSQTELLIAEEKLSPEQEGQLMPRPRYDELTESVEEYVLDMLRDQLNRRQPIDNVSRNLLRLLTATCGYKEVRLLAVQRLEMWLQNPKLTRPAQDLLMSVCMNCNSHGSEDMDVISHLIKIRLKPKVLLNHYMLCIRELLNAHKDNLGTTIKFVIFNELSNARNPNNMQILYTVLQHSSELAPKFLAMVFQDLLTNKDDYLRASRALLREIIKQTKHEINFQAFCLGLMQERKEPQYLEMEFKERFVVHITDVLAVSMMLGITAQVKEAGVAWDKGEKRNLEVLRTFQNQIAAIQRDAVWWLHTVVPSVSKLAPKDYVHCLHKVLFTEQPETYYKWDNWPPESDRNFFLRLCSEVPILEDTLMRVLVIGLSRELPLGPADAMELADHLVKRAAAVQADDVEVLKVERIQLIDAVLNLCTYHHPENIQLPPGYQPPNLAISTLYWKAWPLLLVVAAFNPENIGLAAWEEYPTLKMLMEMVMTNNYSYPPCTLTDEETRTEMINRELQISQREKQEILAFEGHLAAASTKQTITESSSLLLSQLTSLDPQGPPRRPPPHILDQVKALNQSLRLGHLLCRSRNPDFLLHIIQRQASSQSMPWLADLVQSSEGSLDVLPVQCLCEFLLHDAADSTASGEEDDEGESREQKAKKRQRQQKQRQLLGRLQDLLLGPKADEQTTCEVLDYFLRRLGSSQVASRVLAMKGLSLVLSEGGLRDKEEKEPPMEEDIGETDALQGYQWLLRDLPRLPLFDSVRTTTALALQQAIHMETDPQTISAYLIYLSQHTPVEEQGPHSDLALDVARLVVERSTIMAHLFSKPSCSTASDAVLSALLSVFSRYVRRMRKSKEGEEVYSWSESQDQVFLRWSSGETATMHILVVHAMVILLTLGPPRSGDSEFSELLDIWFPEKKPLPTAFLVDTSEEALLLPDWLKLRMIRSEVPRLVDAALQDLEPQQLLLFVQSFGIPVSSMSKLLQYLDQAVAQDPQTLEQNIMDKNYMAHLVEVQHERGASGGQTFHSLLTASLPPRRDSTEAPKPESSPEPPPGQGRTRAGTQVPVLGPEDDLAGIFLQIFPLSPDPRWQSSSPRPLALALQQALGQELARVRQGNPEVPGITVRLLQAMTTLLSSPHGGTLALAMHHSHFLSCPLMRQLYQYQRAVPQDTGFSSLFLKVLMQILQWLDSPAVEDGPLQAQLKLFATRYSARHRISDVRSGLLHLADALSFHGDLEVANSTARAVIATLRSGEKCPVEPELISKVLRGLIEVRSPHLEELLTALFSATTETSCPSPASGPIVVVSSLLLQEKEELLGPSKQEVEGASTEAMRLGPASGLLVDWLETLDPEVVCSCPDLQWKLLFSRRKGKGHISAQVLSFRPYLLALLTHQASWSTLHCCIRVLLGKSREQRLDPSASLDFLWACIHVPRIWQGRDQRTPQKRREELVLHVQGPELLSLVELILSEAETRSQDGDSAARTLIQTRLPLLLSCCRSNDESIGKVTEHLTSCIQQWGDSVLGQRCRDLLLQLYLQRPEVRVPVPEVLLQSEGATSSSICKLDGLVHRFITLLADTSDSRSSESRVADANMACRKLAVAHPVLLLRHLPMIAALLHGRTHLNFQEFRQQNHLAFFLHVLGILELLQPRVFQSEHQGALWDCLRSFIRLLLNYRKSSRHLAPFISKFVQFIHKYVGCSAPAAVAFLQKHAEPLHDLSFDNSDLVMLKSLLAGLSLPSRDGRTDQGLDEEGEDERSAGSLPLVSVSLSTPLTVADVAPHMKRLSRGRAVEDVLETLSDIDEMSRRRPEVLGFFSTNLQRLMSSAEESCRNLAFSLALRSIQNNPSIAADFLPTFMYCLGSRDFEVVQTALRNLPEYTLLCQEHAAVLLHRAFLVGVYGQIDTSAQISEALKILHMEAVM", "length": 2195 }, "evidence": [ { "id": "A0AAA9TV32", "url": "https://omabrowser.org/oma/group/A0AAA9TV32/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q8N201-1", "protein_name": "Integrator complex subunit 1", "gene_name": "INTS1", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MNRAKPTTVRRPSAAAKPSGHPPPGDFIALGSKGQANESKTASTLLKPAPSGLPSERKRDAAAALSSASALTGLTKRPKLSSTPPLSALGRLAEAAVAEKRAISPSIKEPSVVPIEVLPTVLLDEIEAAELEGNDDRIEGVLCGAVKQLKVTRAKPDSTLYLSLMYLAKIKPNIFATEGVIEALCSLLRRDASINFKAKGNSLVSVLACNLLMAAYEEDENWPEIFVKVYIEDSLGERIWVDSPHCKTFVDNIQTAFNTRMPPRSVLLQGEAGRVAGDLGAGSSPHPSLTEEEDSQTELLIAEEKLSPEQEGQLMPRYEELAESVEEYVLDMLRDQLNRRQPIDNVSRNLLRLLTSTCGYKEVRLLAVQKLEMWLQNPKLTRPAQDLLMSVCMNCNTHGSEDMDVISHLIKIRLKPKVLLNHFMLCIRELLSAHKDNLGTTIKLVIFNELSSARNPNNMQVLYTALQHSSELAPKFLAMVFQDLLTNKDDYLRASRALLREIIKQTKHEINFQAFCLGLMQERKEPQYLEMEFKERFVVHITDVLAVSMMLGITAQVKEAGIAWDKGEKRNLEVLRSFQNQIAAIQRDAVWWLHTVVPSISKLAPKDYVHCLHKVLFTEQPETYYKWDNWPPESDRNFFLRLCSEVPILEDTLMRILVIGLSRELPLGPADAMELADHLVKRAAAVQADDVEVLKVGRTQLIDAVLNLCTYHHPENIQLPPGYQPPNLAISTLYWKAWPLLLVVAAFNPENIGLAAWEEYPTLKMLMEMVMTNNYSYPPCTLTDEETRTEMLNRELQTAQREKQEILAFEGHLAAASTKQTITESSSLLLSQLTSLDPQGPPRRPPPHILDQVKSLNQSLRLGHLLCRSRNPDFLLHIIQRQASSQSMPWLADLVQSSEGSLDVLPVQCLCEFLLHDAVDDAASGEEDDEGESKEQKAKKRQRQQKQRQLLGRLQDLLLGPKADEQTTCEVLDYFLRRLGSSQVASRVLAMKGLSLVLSEGSLRDGEEKEPPMEEDVGDTDVLQGYQWLLRDLPRLPLFDSVRSTTALALQQAIHMETDPQTISAYLIYLSQHTPVEEQAQHSDLALDVARLVVERSTIMSHLFSKLSPSAASDAVLSALLSIFSRYVRRMRQSKEGEEVYSWSESQDQVFLRWSSGETATMHILVVHAMVILLTLGPPRADDSEFQALLDIWFPEEKPLPTAFLVDTSEEALLLPDWLKLRMIRSEVLRLVDAALQDLEPQQLLLFVQSFGIPVSSMSKLLQFLDQAVAHDPQTLEQNIMDKNYMAHLVEVQHERGASGGQTFHSLLTASLPPRRDSTEAPKPKSSPEQPIGQGRIRVGTQLRVLGPEDDLAGMFLQIFPLSPDPRWQSSSPRPVALALQQALGQELARVVQGSPEVPGITVRVLQALATLLSSPHGGALVMSMHRSHFLACPLLRQLCQYQRCVPQDTGFSSLFLKVLLQMLQWLDSPGVEGGPLRAQLRMLASQASAGRRLSDVRGGLLRLAEALAFRQDLEVVSSTVRAVIATLRSGEQCSVEPDLISKVLQGLIEVRSPHLEELLTAFFSATADAASPFPACKPVVVVSSLLLQEEEPLAGGKPGADGGSLEAVRLGPSSGLLVDWLEMLDPEVVSSCPDLQLRLLFSRRKGKGQAQVPSFRPYLLTLFTHQSSWPTLHQCIRVLLGKSREQRFDPSASLDFLWACIHVPRIWQGRDQRTPQKRREELVLRVQGPELISLVELILAEAETRSQDGDTAACSLIQARLPLLLSCCCGDDESVRKVTEHLSGCIQQWGDSVLGRRCRDLLLQLYLQRPELRVPVPEVLLHSEGAASSSVCKLDGLIHRFITLLADTSDSRALENRGADASMACRKLAVAHPLLLLRHLPMIAALLHGRTHLNFQEFRQQNHLSCFLHVLGLLELLQPHVFRSEHQGALWDCLLSFIRLLLNYRKSSRHLAAFINKFVQFIHKYITYNAPAAISFLQKHADPLHDLSFDNSDLVMLKSLLAGLSLPSRDDRTDRGLDEEGEEESSAGSLPLVSVSLFTPLTAAEMAPYMKRLSRGQTVEDLLEVLSDIDEMSRRRPEILSFFSTNLQRLMSSAEECCRNLAFSLALRSMQNSPSIAAAFLPTFMYCLGSQDFEVVQTALRNLPEYALLCQEHAAVLLHRAFLVGMYGQMDPSAQISEALRILHMEAVM", "length": 2190 }, "evidence": [ { "id": "A0AAA9TV32", "url": "https://omabrowser.org/oma/group/A0AAA9TV32/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "Q9W1C5-1", "protein_name": "Integrator complex subunit 1", "gene_name": "IntS1", "tax_id": 7227, "organism": "Drosophila melanogaster", "sequence": { "sequence": "MDRGKGSGSNRSQKKVPLGGELFALGKSVRDDSKSKILPIKGMSSSDRKREASTALASSSKRFRGNLKDAGAPDMSSGSSQCETWEQFAVDCDLDTVVETIYAALEQNDSETVGRLVCGVIKQTTTSSSRSKVDNIALLALIYVAKVQPSIFCTDIVACALLSFLRREANVKMRYNTNLHILFANLLTRGFMEISQWPEVLLRIYIDDAVNERYWADNELCAPLVKNICAAFKTRTPHISLLRWDVSSSLPSGQAHRDSMTVDDDSGDNSTQSLDASPLNTESEPIPDAMCTTKSRFSDAVVQKHVSDAIRDQLNKRQQQDNYTRNFLKFLCTTSGIAEVRCLSISRLELWIHNGKLVKFAQQLLSYICFNIKGRNTQDNEVLLVLVKMRLKTKPLINHYMSCLKEMIFLQPEILSTVMKLVVQNELSNTRNPNNMGMLATMFQTSADQSAATLAEIYQEFLLQRDDCLRTLRVFLRELVRMLRFDVNLVKFCKTFLSEREDLTPQIEMFEFKERIFNSMVDIVCLCMFLSATPQAREASLSLKTNRDTKNNHALLKLYNQMSQIQLDTVSWMYETVPTLFKIPAAEYHQALHKLLLLDSPEQYSRCDQWPSEPERGAILRIISETPIHEETLLRIILIGITKDIPFSIANTFDVLLLVIKRVSGMKATNIPAVQANKFDIIDFLFSMSEYHHPENIRLPAEYEPPKLAIIAFYWKAWLILLMISAHNPSSFGAFCWDHYPTMKMMMEICITNQFNNSSATKDELQIITMERDHILQFETYLAAQTSPHAVITEETAILITQLMLMDPMGTPRKVPSMVLDQLKFLNQTYKLGHLFCRCRKPDLLLDIIQRQGTTQSMPWLSDLVQNSEGDFSHLPVQCLCEFLLFNAHIINEENSRDAELVNFLRNLIFDGNLSHQIVCELLDYIFRRLSSTVKQSRVAALSGLKIIFRHSGDFENEWLLKSLQQIPHFYEVKPFIIPQLRAACQVENCPELIMAYIQFITAHTLNDPVNEMLDHVIDMAQLIVERSTMFQHIIISQEDYDYVPDENRIQTLKCLFVMFNNYIIKLREYHEPYEWTEYPDLLMVQFDDGVQLPLHINIIHAFIILLTYSNSNMPESIPILDYWFPPGRPAPVAFLPSMPQEQVQLLPDWLKLKMIRSSVDRLIEAALNDLTPDQIVLFVQNFGTPVNSMSKLLAMLDTAVLEQFDLVKNAILNKAYLAQLIEIQQARGAKNGHYTVQALDLHSHSQTVPDLPKISVVIQEAVEIDDYDSSDSDDRPTNFLATKEVAQTILTQPDQLTESRSDCRSLIQKLLDMLASPNSNRADVVNAITEVLAVGCSVTMSRHACTFLRTFFSCMLHSDKYHILENALQKNLSMFKHTFADSSLLQKSELYHESLVFMLRNSREIYAQQFKANTALVARKRIVRAIVQSFDQTKDSKTVAKSKSDQLFHNGLFIDWLSEMDPEIVSTQLMKERFLFSKSCSEFRFYLLSLINHQTNWDTIERIAEYLFKNFHEDYDYATVLNYFEALTTNPKLWKGRDKYMSKNVRPDAFFMLRTSELEPFSHFILHEGLSEVKLDSKNYDFKLCSRMNLLFKLTEKRRDLMVKVMEHVEKSSVSDYLKLQVLQQMYIMYPRIKFLKPGKTGEQAYKLQNLKGCQADKVSNNLITCLGSLVGKKDFETLSTDTELLLRKLAASHPLLFLRQLGVLSSIMQGRAQLSMKALREEHHFHRFVQILRTLELLQPTIFEEAYKNEIQNTLSCYFNFFKHHSNVKEACQMLNKFVQMLQAYINYNPSSALLFIEQYVGILKELAAKYTSLGKLQVLVQAVALLQHKSHSATELDDEEVKYEYDLDEHFDVKPSASKPVVTEDPIEVNPQTPIDPSSSRGPLSVLTLGSYSRSNYTDISPHFLDLVKIIKQSNTEDVVLGPMQELECLTSKRFVFINELFERLLNLIFSPSAQIRSIAFIILIRHLKHNPGNSDINLCTLNAYIQCLRDENSSVAATAIDNLPEMSVLLQEHAIDILTVAFSLGLKSCLNTGHQIRKVLQTLVIQHGY", "length": 2053 }, "evidence": [ { "id": "A0AAA9TV32", "url": "https://omabrowser.org/oma/group/A0AAA9TV32/", "database": "OMA" } ], "glygen_name": "Fruit fly", "common_name": "Fruit fly" } ], "go_annotation": { "categories": [ { "name": "Biological Process", "total": 3, "go_terms": [ { "name": "U2 snRNA 3'-end processing", "id": "GO:0034474", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0034474", "evidence": [ { "database": "UniProtKB", "id": "A0AAA9TV32", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TV32" } ], "pmid": "" }, { "name": "regulation of transcription elongation by RNA polymerase II", "id": "GO:0034243", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0034243", "evidence": [ { "database": "UniProtKB", "id": "A0AAA9TV32", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TV32" } ], "pmid": "" }, { "name": "RNA polymerase II transcription initiation surveillance", "id": "GO:0160240", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0160240", "evidence": [ { "database": "UniProtKB", "id": "A0AAA9TV32", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TV32" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 2, "go_terms": [ { "name": "integrator complex", "id": "GO:0032039", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0032039", "evidence": [ { "database": "UniProtKB", "id": "A0AAA9TV32", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TV32" } ], "pmid": "" }, { "name": "INTAC complex", "id": "GO:0160232", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0160232", "evidence": [ { "database": "UniProtKB", "id": "A0AAA9TV32", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TV32" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 394, "end_pos": 396, "annotation": "n_glycosylation_sequon" }, { "start_pos": 774, "end_pos": 776, "annotation": "n_glycosylation_sequon" }, { "start_pos": 857, "end_pos": 859, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A0AAA9TV32", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TV32" }, { "id": "PF22929", "database": "Pfam", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF22929" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "Integrator complex subunit 1 INTS2-binding", "eco_id": "ECO_0000259", "start_pos": 970, "end_pos": 1304, "start_aa": "Glu", "end_aa": "Phe", "glycosite_overlap": [] }, { "evidence": [ { "id": "A0AAA9TV32", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TV32" }, { "id": "PF22927", "database": "Pfam", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF22927" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "Integrator complex subunit 1 R3", "eco_id": "ECO_0000259", "start_pos": 1834, "end_pos": 1991, "start_aa": "Leu", "end_aa": "Ser", 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"Protein Classification" ] }, { "id": "PF15683", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF15683", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "A0AAA9TV57", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TV57", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0AAA9TV57-1", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TV57-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0AAA9TVJ2", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TVJ2", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0AAA9TVJ2-1", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TVJ2-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "F1MF67", "url": "https://www.uniprot.org/uniprotkb/F1MF67", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "F1MF67-1", "url": "https://www.uniprot.org/uniprotkb/F1MF67-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { 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isoform of Testis development related protein OS=Bos taurus OX=9913 GN=TDRP PE=4 SV=1 CANONICAL=A0AAA9TVJ2-1" }, "locus": { "chromosome": "1", "start_pos": 146608117, "end_pos": 146562510, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000088168.1", "url": "https://www.ensembl.org/id/ENSBTAT00000088168.1" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000101279.1", "url": "https://www.ensembl.org/id/ENSBTAP00000101279.1" } ] } }, { "isoform_ac": "A0AAA9TVJ2-1", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TVJ2/entry", "sequence": { "sequence": "MWKLGRSRVLLDEPPEEEDGLRGGAPPATAPAAAQVRGRRGGGARGAGRVMRVGMSGAEAWPRSGGGAQVGRAGEARAARPFNFPRLVRARPLCPVVTAPPATLRMTEPSAPPPLARVWDGGRSSRRWEPRAVAFQRRGGNCLPSGRDPGPGPGPSVQRRVRGRAPGWAGFTGEAWTGGGHRPAGEVPGATFRGWKEVTSLFNKDDEQQLLEGRKSPKSRATNLRLKEELKTEKKSGFWDNLVLKQNIQSKKPDEIEGWEPPKLALEDVAADSGGPVSDRVSRPGWQEDTKGSSKYTSLAGAGSSSRWSLRSAGKLVSIRRQSRGHLTDDWEELE", "length": 335, "header": "tr|A0AAA9TVJ2-1|A0AAA9TVJ2_BOVIN Isoform 1 of Testis development related protein OS=Bos taurus OX=9913 GN=TDRP PE=4 SV=1 CANONICAL=A0AAA9TVJ2-1" }, "locus": { "chromosome": "1", "start_pos": 146607376, "end_pos": 146562510, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000118708.1", "url": "https://www.ensembl.org/id/ENSBTAT00000118708.1" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000100597.1", "url": "https://www.ensembl.org/id/ENSBTAP00000100597.1" } ] } }, { "isoform_ac": "F1MF67-1", "url": "https://www.uniprot.org/uniprotkb/F1MF67/entry", "sequence": { "sequence": "MWKLGRSRVLLDEPPEEEDGLRGGAPPATAPAAAQVPGATFRGWKEVTSLFNKDDEQQLLEGRKSPKSRATNLRLKEELKTEKKSGFWDNLVLKQNIQSKKPDEIEGWEPPKLALEDVAADSGGPVSDRVSRPGWQEDTKGSSNSRWSLRSAGKLVSIRRQSRGHLTDDWEELE", "length": 174, "header": "tr|F1MF67-1|A0AAA9TVJ2_BOVIN Computationally mapped isoform of Testis development related protein OS=Bos taurus OX=9913 GN=TDRP PE=4 SV=4 CANONICAL=A0AAA9TVJ2-1" }, "locus": { "chromosome": "1", "start_pos": 146607376, "end_pos": 146562510, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000061350.4", "url": "https://www.ensembl.org/id/ENSBTAT00000061350.4" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000053800.4", "url": "https://www.ensembl.org/id/ENSBTAP00000053800.4" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [ { "id": "bta:614166", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?bta:614166", "resource": "KEGG Pathway" } ], "orthologs": [], "go_annotation": { "categories": [ { "name": "Biological Process", "total": 1, "go_terms": [ { "name": "spermatogenesis", "id": "GO:0007283", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007283", "evidence": [ { "database": "UniProtKB", "id": "A0AAA9TVJ2", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TVJ2" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 2, "go_terms": [ { "name": "nucleus", "id": "GO:0005634", 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"categories": [ "Enzyme and Pathway" ] }, { "id": "FNEKEYC", "url": "https://omabrowser.org/oma/group/FNEKEYC/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "F1MRQ7", "url": "https://www.orthodb.org/?gene=F1MRQ7", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR12232", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR12232", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR12232:SF1", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR12232:SF1", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF04908", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF04908", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "A0AAA9TVI1", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TVI1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0AAA9TVI1-1", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TVI1-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0ABI0NUS9", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NUS9", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0ABI0NUS9-1", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NUS9-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "F1MRQ7", "url": "https://www.uniprot.org/uniprotkb/F1MRQ7", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "F1MRQ7-1", "url": "https://www.uniprot.org/uniprotkb/F1MRQ7-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MSQLYVDIYPLLLEPPSHPSVAAAIYVIAEHRAELPALHSSFPLAVLHVLVCASLLLLQSVPPSPSLLCSPVQSLHMCLCSALWRGSPIRKKQQEVVGFLEANKIDFKEFDIAGDEDNRKWMRENVPGEKKPQNGIPLPPQIFNEEQYCGDFDSFFSAKEENIIYSFLGLAPPPGSKVTKSPEEASSLPDGEVAGEAQSTTEGTEKAEESGEQEAQKEGDEDAGDLAGSQEKDEEEEETAAEETKEVTTEGAEGEAEGEEAEEEEEEPGEEEEEGDEEEES", "length": 281, "header": "tr|A0AAA9TVI1-1|A0AAA9TVI1_BOVIN Isoform 1 of SH3 domain binding glutamate rich protein OS=Bos taurus OX=9913 GN=SH3BGR PE=3 SV=1 CANONICAL=A0AAA9TVI1-1" }, "isoforms": [ { "isoform_ac": "A0AAA9TVI1-1", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TVI1/entry", "sequence": { "sequence": "MSQLYVDIYPLLLEPPSHPSVAAAIYVIAEHRAELPALHSSFPLAVLHVLVCASLLLLQSVPPSPSLLCSPVQSLHMCLCSALWRGSPIRKKQQEVVGFLEANKIDFKEFDIAGDEDNRKWMRENVPGEKKPQNGIPLPPQIFNEEQYCGDFDSFFSAKEENIIYSFLGLAPPPGSKVTKSPEEASSLPDGEVAGEAQSTTEGTEKAEESGEQEAQKEGDEDAGDLAGSQEKDEEEEETAAEETKEVTTEGAEGEAEGEEAEEEEEEPGEEEEEGDEEEES", "length": 281, "header": "tr|A0AAA9TVI1-1|A0AAA9TVI1_BOVIN Isoform 1 of SH3 domain binding glutamate rich protein OS=Bos taurus OX=9913 GN=SH3BGR PE=3 SV=1 CANONICAL=A0AAA9TVI1-1" }, "locus": { "chromosome": "1", "start_pos": 139596779, "end_pos": 139458238, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000087811.2", "url": "https://www.ensembl.org/id/ENSBTAT00000087811.2" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000102622.1", "url": "https://www.ensembl.org/id/ENSBTAP00000102622.1" } ] } }, { "isoform_ac": "A0ABI0NUS9-1", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NUS9/entry", "sequence": { "sequence": "MVIKVFVATSSGSIAIRKKQQEVVGFLEANKIDFKEFDIAGDEDNRKWMRENVPGEKKPQNGIPLPPQIFNEEQYCGDFDSFFSAKEENIIYSFLGLAPPPGSKVTKSPEEASSLPDGEVAGEAQSTTEGTEKAEESGEQEAQKEGDEDAGDLAGSQEKDEEEEETAAEETKEVTTEGAEGEAEGEEAEEEEEEPGEEEEEGDEEEES", "length": 208, "header": "tr|A0ABI0NUS9-1|A0ABI0NUS9_BOVIN Computationally mapped isoform of SH3 domain binding glutamate rich protein OS=Bos taurus OX=9913 GN=SH3BGR PE=3 SV=1 CANONICAL=A0AAA9TVI1-1" }, "locus": { "chromosome": "1", "start_pos": 139596779, "end_pos": 139528965, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000138731.1", "url": "https://www.ensembl.org/id/ENSBTAT00000138731.1" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000107570.1", "url": "https://www.ensembl.org/id/ENSBTAP00000107570.1" } ] } }, { "isoform_ac": "F1MRQ7-1", "url": "https://www.uniprot.org/uniprotkb/F1MRQ7/entry", "sequence": { "sequence": "MNKQIRKKQQEVVGFLEANKIDFKEFDIAGDEDNRKWMRENVPGEKKPQNGIPLPPQIFNEEQYCGDFDSFFSAKEENIIYSFLGLAPPPGSKVTKSPEEASSLPDGEVAGEAQSTTEGTEKAEESGEQEAQKEGDEDAGDLAGSQEKDEEEEETAAEETKEVTTEGAEGEAEGEEAEEEEEEPGEEEEEGDEEEES", "length": 197, "header": "tr|F1MRQ7-1|A0AAA9TVI1_BOVIN Computationally mapped isoform of SH3 domain binding glutamate rich protein OS=Bos taurus OX=9913 GN=SH3BGR PE=3 SV=3 CANONICAL=A0AAA9TVI1-1" }, "locus": { "chromosome": "1", "start_pos": 139596779, "end_pos": 139530393, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000036848.6", "url": "https://www.ensembl.org/id/ENSBTAT00000036848.6" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000036700.5", "url": "https://www.ensembl.org/id/ENSBTAP00000036700.5" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [ { "id": "bta:617797", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?bta:617797", "resource": "KEGG Pathway" } ], "orthologs": [ { "uniprot_canonical_ac": "I3LEV7-1", "protein_name": "SH3 domain binding glutamate rich protein", "gene_name": "SH3BGR", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MVIKVFVATSSGSIAIRKKQQEVVGFLEANKIDFKEFDIAGDEDNRRWMRENVPGEKKPQNGIPLPPQIFNEEQYCGDFDSFFSAKEENIIYSFLGLAPPPGSKVTKSPEEASSLPNGDVAGEAQSTTEGAEKPGDGGEQEAQKEESEEAGDLGGSQEKHEEEGETAPEEAGDVTEEGAEGEAEDEEAEAGEEEPGDDEEAEEDS", "length": 205 }, "evidence": [ { "id": "A0AAA9TVI1", "url": "https://omabrowser.org/oma/group/A0AAA9TVI1/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "P55822-1", "protein_name": "SH3 domain-binding glutamic acid-rich protein", "gene_name": "SH3BGR", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MPLLLLGETEPLKLERDCRSPVDPWAAASPDLALACLCHCQDLSSGAFPDRGVLGGVLFPTVEMVIKVFVATSSGSIAIRKKQQEVVGFLEANKIDFKELDIAGDEDNRRWMRENVPGEKKPQNGIPLPPQIFNEEQYCGDFDSFFSAKEENIIYSFLGLAPPPDSKGSEKAEEGGETEAQKEGSEDVGNLPEAQEKNEEEGETATEETEEIAMEGAEGEAEEEEETAEGEEPGEDEDS", "length": 239 }, "evidence": [ { "id": "A0AAA9TVI1", "url": "https://omabrowser.org/oma/group/A0AAA9TVI1/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "Q9WUZ7-1", "protein_name": "SH3 domain-binding glutamic acid-rich protein", "gene_name": "Sh3bgr", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MVIKVFVATSSGSIAIRKKQQEVVGFLEANKIDFKELDIAGDEDNRKWMRENVPGEKKPQNGIPLPPQIFNEEQYCGDFDSFFSAKEENIIYSFLGLAPPPGSKVTKSEEASSLPNGDVAGEAEGAAEGTEKAEKSGENEAQKEDSEDTGELSESQEKKEEEGEDGEEGEEGEEREEGGEGETTGETEEAPEEGAGGEAEEEEPEEEAGEGEDS", "length": 214 }, "evidence": [ { "id": "A0AAA9TVI1", "url": "https://omabrowser.org/oma/group/A0AAA9TVI1/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" } ], "go_annotation": { "categories": [ { "name": "Molecular Function", "total": 1, "go_terms": [ { "name": "protein-macromolecule adaptor activity", "id": "GO:0030674", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030674", "evidence": [ { "database": "UniProtKB", "id": "A0AAA9TVI1", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TVI1" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" }, { "name": "homologset.oma", "label": "OMA Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ], "tool_support": { "graph_view": "yes" } }, { "uniprot_canonical_ac": "A0AAA9TVJ4-1", "uniprot_ac": "A0AAA9TVJ4", "uniprot_id": "A0AAA9TVJ4_BOVIN", "mass": { "chemical_mass": 38519.0, "monoisotopic_mass": 38519.0 }, "refseq": { "ac": "XP_024851759", "name": "rho guanine nucleotide exchange factor 39 isoform X1", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_024851759" }, "gene_names": [ { "name": "ARHGEF39", "type": "recommended", "evidence": [ { "id": "A0AAA9TVJ4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TVJ4" } ] }, { "name": "ARHGEF39", "type": "synonym", "evidence": [ { "id": "XP_024851759", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_024851759" } ] }, { "name": "C8H9orf100", "type": "synonym", "evidence": [ { "id": "XP_024851759", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_024851759" } ] }, { "name": "C9orf100", "type": "synonym", "evidence": [ { "id": "XP_024851759", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_024851759" } ] } ], "protein_names": [ { "name": "Rho guanine nucleotide exchange factor 39", "type": "synonym", "evidence": [ { "id": "A0AAA9TVJ4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TVJ4/entry#names_and_taxonomy" } ] }, { "name": "rho guanine nucleotide exchange factor 39 isoform X1", "type": "synonym", "evidence": [ { "id": "XP_024851759", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_024851759" } ] } ], "function": [], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Bos taurus", "taxid": 9913, "evidence": [ { "database": "UniProtKB", "id": "A0AAA9TVJ4", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TVJ4" } ], "common_name": "Bovine", "glygen_name": "Bovine", "reference_species": "Bos taurus [9913]" } ], "gene": [ { "name": "ARHGEF39", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TVJ4", "locus": { "chromosome": "8", "start_pos": 59835788, "end_pos": 59846543, "strand": "+", "evidence": [ { "database": "Ensembl Gene", "id": "ENSBTAG00000011416", "url": "https://www.ensembl.org/id/ENSBTAG00000011416" } ] } } ], "crossref": [ { "id": "A0AAA9TVJ4", "url": "https://alphafold.ebi.ac.uk/entry/A0AAA9TVJ4", "database": "AlphaFoldDB", "categories": [] }, { "id": "780881", "url": "https://www.ncbi.nlm.nih.gov/gene/780881", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR000219", "url": "https://www.ebi.ac.uk/interpro/entry/IPR000219", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR001849", "url": "https://www.ebi.ac.uk/interpro/entry/IPR001849", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR011993", "url": "https://www.ebi.ac.uk/interpro/entry/IPR011993", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR035899", "url": "https://www.ebi.ac.uk/interpro/entry/IPR035899", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR042987", "url": "https://www.ebi.ac.uk/interpro/entry/IPR042987", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "PTHR47056", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR47056", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR47056:SF1", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR47056:SF1", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00621", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00621", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "XP_024851759", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_024851759", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0AAA9TVJ4", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TVJ4", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0AAA9TVJ4-1", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TVJ4-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0AAF6YWH9", "url": "https://www.uniprot.org/uniprotkb/A0AAF6YWH9", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0AAF6YWH9-1", "url": "https://www.uniprot.org/uniprotkb/A0AAF6YWH9-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MESPAPGARCPVQEQRARWERKRACTARELLETERRYQEQLGLVATYFVAILRAKGTLRPPERQALFGPWELIYGASQELLPYLEGGRWGQGLEGFCNHLELYTQFAANVERSRTILQEQLKKNKHFRRFVRLQEGRPEFGGLQLQDLLPLPLQRLQQYENLAVALAENTGPNSPEHKQLTRAAQLISETAQRVHTIGQKQKNEQHLQRIQALLSGRQAKGLISGRWFLRQGWLLVVPPRGEPRPRMFFLFSDALLMAKPRPPLHLLQSGTFACRALYPMGECQLHRVFGHSGGPCGGLLSQPEELAESYNSRVQDTVGIGQNQGYKGILLTKHGLFMV", "length": 339, "header": "tr|A0AAA9TVJ4-1|A0AAA9TVJ4_BOVIN Isoform 1 of Rho guanine nucleotide exchange factor 39 OS=Bos taurus OX=9913 GN=ARHGEF39 PE=4 SV=1 CANONICAL=A0AAA9TVJ4-1" }, "isoforms": [ { "isoform_ac": "A0AAA9TVJ4-1", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TVJ4/entry", "sequence": { "sequence": "MESPAPGARCPVQEQRARWERKRACTARELLETERRYQEQLGLVATYFVAILRAKGTLRPPERQALFGPWELIYGASQELLPYLEGGRWGQGLEGFCNHLELYTQFAANVERSRTILQEQLKKNKHFRRFVRLQEGRPEFGGLQLQDLLPLPLQRLQQYENLAVALAENTGPNSPEHKQLTRAAQLISETAQRVHTIGQKQKNEQHLQRIQALLSGRQAKGLISGRWFLRQGWLLVVPPRGEPRPRMFFLFSDALLMAKPRPPLHLLQSGTFACRALYPMGECQLHRVFGHSGGPCGGLLSQPEELAESYNSRVQDTVGIGQNQGYKGILLTKHGLFMV", "length": 339, "header": "tr|A0AAA9TVJ4-1|A0AAA9TVJ4_BOVIN Isoform 1 of Rho guanine nucleotide exchange factor 39 OS=Bos taurus OX=9913 GN=ARHGEF39 PE=4 SV=1 CANONICAL=A0AAA9TVJ4-1" }, "locus": { "chromosome": "8", "start_pos": 59840097, "end_pos": 59836792, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000117900.1", "url": "https://www.ensembl.org/id/ENSBTAT00000117900.1" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000101437.1", "url": "https://www.ensembl.org/id/ENSBTAP00000101437.1" } ] } }, { "isoform_ac": "A0AAF6YWH9-1", "url": "https://www.uniprot.org/uniprotkb/A0AAF6YWH9/entry", "sequence": { "sequence": "GSVTSAPPIWYHQFLCDLSKYFVAILRAKGTLRPPERQALFGPWELIYGASQELLPYLEGGRWGQGLEGFCNHLELYTQFAANVERSRTILQEQLKKNKHFRRFVRLQEGRPEFGGLQLQDLLPLPLQRLQQYENLAVALAENTGPNSPEHKQLTRAAQLISETAQRVHTIGQKQKNEQHLQRIQALLSGRQAKGLISGRWFLRQGWLLVVPPRGEPRPRMFFLFSDALLMAKPRPPLHLLQSGTFACRALYPMGECQLHRVFGHSGGPCGGLLSLSFPHEKLLLMSTDQEELSHWYHSLTLAISSQKN", "length": 309, "header": "tr|A0AAF6YWH9-1|A0AAF6YWH9_BOVIN Computationally mapped isoform of Rho guanine nucleotide exchange factor 39 OS=Bos taurus OX=9913 GN=ARHGEF39 PE=4 SV=1 CANONICAL=A0AAA9TVJ4-1" }, "locus": { "chromosome": "8", "start_pos": 59842258, "end_pos": 59836893, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000015167.5", "url": "https://www.ensembl.org/id/ENSBTAT00000015167.5" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000015167.4", "url": "https://www.ensembl.org/id/ENSBTAP00000015167.4" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [], "orthologs": [], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 1, "go_terms": [ { "name": "plasma membrane", "id": "GO:0005886", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005886", "evidence": [ { "database": "UniProtKB", "id": "A0AAA9TVJ4", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TVJ4" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 1, "go_terms": [ { "name": "positive regulation of cell migration", "id": "GO:0030335", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030335", "evidence": [ { "database": "UniProtKB", "id": "A0AAA9TVJ4", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TVJ4" } ], "pmid": "" } ] }, { "name": "Molecular Function", "total": 1, "go_terms": [ { "name": "guanyl-nucleotide exchange factor activity", "id": "GO:0005085", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005085", "evidence": [ { "database": "UniProtKB", "id": "A0AAA9TVJ4", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TVJ4" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A0AAA9TVJ4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TVJ4" }, { "id": "PS50010", "database": "PROSITE", "url": "https://prosite.expasy.org/PS50010" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "DH", "eco_id": "ECO_0000259", "start_pos": 22, "end_pos": 197, "start_aa": "Lys", "end_aa": "Ile", "glycosite_overlap": [] } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" } ], 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"sequence": { "sequence": "MAPAQRCPLCRQTFFCGRGHVYSRKHQRQLKVALERLLPQVEAARKAVRAAQVERYVPEHERWCWCLCCGCEVRKHLSHGNLTVLHGGLLGHLASPEHKKATNKFWWENKAEFQMKEKFLISPQDFARFKKSMVKSLDSYEEKEDEVIKEMAAQIREVEQSRQEMVRSVLEPQTVPDPEEGSSAPGSRKGTNSQVASTSQQPSYLDLPPAPELDWMETGQPLTFIGHQDTPGIGNIHSEKHLMKNLYLQYMKTSQNSAGFPGGTTGATPPWMVQDEDCSSGNQQIGPSYEEFLKEKEKQKLKKLPPDRVGANFDHSSSTSAGWLPSFGRVWNNGRRWQSRHQFKTEAAARNKQQSHKGKTLMAS", "length": 364, "header": "tr|F6PMQ1-1|F6PMQ1_BOVIN Computationally mapped isoform of Centrosomal AT-AC splicing factor OS=Bos taurus OX=9913 GN=CENATAC PE=4 SV=2 CANONICAL=A0AAA9TVP6-1" }, "locus": { "chromosome": "15", "start_pos": 29588586, "end_pos": 29580785, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000023847.7", "url": "https://www.ensembl.org/id/ENSBTAT00000023847.7" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000023847.6", "url": "https://www.ensembl.org/id/ENSBTAP00000023847.6" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": 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catabolic process", "id": "GO:0042176", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0042176", "evidence": [ { "database": "UniProtKB", "id": "A0AAA9TVP6", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TVP6" } ], "pmid": "" }, { "name": "negative regulation of centrosome duplication", "id": "GO:0010826", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0010826", "evidence": [ { "database": "UniProtKB", "id": "A0AAA9TVP6", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TVP6" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 81, "end_pos": 83, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" } ], "sequence_features": { 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"MATTSTASTTSTTGSTLLQPLSNAVRLPIDQVNFVVCQLFALLAAIWFRTYLHSSKTSSFIRHVVATLLGLYLALFCFGWYCFVFALGYLTVCQITRVYIFDYGQYSADFSGPMMIITQKITSLAYEIHDGMFRKDEELTPSQRGLAVRRMPSLLEYLSYNCNFMGILAGPLCSYKDYITFIEGRSYHMTQSGEDGKEEIQYERTEPSPNVAVIQKLLVCGLSLLFHLIISKMLPVEYNIDEHFQATASWPTKVIYLYVSLLAARPKYYFAWTLADAINNAAGFGFRGYDKNGAARWDLISNLRIKQIEMSTSFKMFLDNWNIQTALWLKRVCYERASLSPTTQTFFLSAIWHGVYPGYYLTFLTGMLMTLVARAVRNNFRHYFIEPPQLKFLYDVITWIATQIAISYTVVPFVLLSVKASLMFYSSWYYSLHFACILVLLLLPVKKTQKGKSTHENVQLSRSKKFDEKDNSLGQNSFFRTNSVCNQNQEITSRHSSLKQ", "length": 500, "header": "tr|A0AAA9SQZ5-1|A0AAA9TVQ6_BOVIN Computationally mapped isoform of Membrane bound O-acyltransferase domain containing 2 OS=Bos taurus OX=9913 GN=MBOAT2 PE=4 SV=1 CANONICAL=A0AAA9TVQ6-1" }, "locus": { "chromosome": "11", "start_pos": 88464682, "end_pos": 88363149, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000128421.2", "url": "https://www.ensembl.org/id/ENSBTAT00000128421.2" }, { "database": "Ensembl Peptide", "id": 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GN=PGM2 PE=1 SV=2 CANONICAL=A0AAA9TVU2-1" }, "isoforms": [ { "isoform_ac": "A0AAA9TVU2-1", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TVU2/entry", "sequence": { "sequence": "TRAPGGGDAGMDSRLDQETAQWLRWDKNPLTLASVKQLIAAGNTEELQKCFSARMEFGTAGLRAAMGAGISHMNDLTIIQTTQGFCRYLEKQFSDLKQRGVVISFDARAHPASGGSSRRFARLAATTFISQGIPVYLFSDITPTPFVPYTVSHLKLCAGIMITASHNPKQDNGYKVYWDNGAQIISPHDKGISQAIEENLEPWPQAWDDSVLNGSLLLHDPSASINKDYFEDLKKYCFHRAVNKETKVKFVHTSVHGVGHSFVQSAFKAFDFVPPEAVSEQKDPDPEFPTVKYPNPEEGKGVLTLSFALADKIKAKIILANDPDADRLAVAEKQDSGKWKVFSGNELGALLGWWLFTSWKEKNQDHSALQNLYMLSSTVSSKILRAIALKEGFHFEETLTGFKWMGNRAKQLIDQGKNVLFAFEEAIGYMCCPFVLDKDGVSAAVITAELASFLATKNLSLSQQLKAIYVEYGYHITRASYFICHDQETIKQLFENLRNYDGKSNYPKTCGRFEISHIRDLTTGYDDNEPDKKAILPTSKSSQMITFSFANGGVATMRTSGTEPKIKYYLELCAPPGNSDPEQLKKELDELVSAVEEHFFQPQKYNLQPKGE", "length": 612, "header": "tr|A0AAA9TVU2-1|A0AAA9TVU2_BOVIN Isoform 1 of Phosphoglucomutase 2 OS=Bos taurus OX=9913 GN=PGM2 PE=1 SV=2 CANONICAL=A0AAA9TVU2-1" }, "locus": { "chromosome": "6", "start_pos": 57181140, "end_pos": 57145086, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000128067.2", "url": "https://www.ensembl.org/id/ENSBTAT00000128067.2" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000100716.2", "url": "https://www.ensembl.org/id/ENSBTAP00000100716.2" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [], "orthologs": [], "go_annotation": { "categories": [ { "name": "Molecular Function", "total": 3, "go_terms": [ { "name": "magnesium ion binding", "id": "GO:0000287", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000287", "evidence": [ { "database": "UniProtKB", "id": "A0AAA9TVU2", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TVU2" } ], "pmid": "" }, { "name": "phosphoglucomutase activity", "id": "GO:0004614", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0004614", "evidence": [ { "database": "UniProtKB", "id": "A0AAA9TVU2", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TVU2" } ], "pmid": "" }, { "name": "phosphopentomutase activity", "id": "GO:0008973", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008973", "evidence": [ { "database": "UniProtKB", "id": "A0AAA9TVU2", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TVU2" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 1, "go_terms": [ { "name": "cytosol", "id": "GO:0005829", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005829", "evidence": [ { "database": "UniProtKB", "id": "A0AAA9TVU2", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TVU2" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 2, "go_terms": [ { "name": "glycogen biosynthetic process", "id": "GO:0005978", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005978", "evidence": [ { "database": "UniProtKB", "id": "A0AAA9TVU2", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TVU2" } ], "pmid": "" }, { "name": "glycogen catabolic process", "id": "GO:0005980", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005980", "evidence": [ { "database": "UniProtKB", "id": "A0AAA9TVU2", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TVU2" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 213, "end_pos": 215, "annotation": "n_glycosylation_sequon" }, { "start_pos": 458, "end_pos": 460, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A0AAA9TVU2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TVU2" }, { "id": "PF02878", "database": "Pfam", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF02878" }, { "id": "PF02879", "database": "Pfam", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF02879" }, { "id": "PF02880", "database": "Pfam", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF02880" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "Alpha-D-phosphohexomutase alpha/beta/alpha", "eco_id": "ECO_0000259", "start_pos": 55, "end_pos": 200, "start_aa": "Met", "end_aa": "Leu", "glycosite_overlap": [] } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 213, "end_pos": 215 }, { "start_pos": 458, "end_pos": 460 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ], "tool_support": { "graph_view": "yes" } }, { "uniprot_canonical_ac": "A0AAA9TVW2-1", "uniprot_ac": "A0AAA9TVW2", "uniprot_id": "A0AAA9TVW2_BOVIN", "mass": { "chemical_mass": 21521.0, "monoisotopic_mass": 21521.0 }, "refseq": {}, "gene_names": [ { "name": "HINT3", "type": "recommended", "evidence": [ { "id": "A0AAA9TVW2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TVW2" } ] } ], "protein_names": [ { "name": "Adenosine 5'-monophosphoramidase HINT3", "type": "recommended", "evidence": [ { "id": "A0AAA9TVW2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TVW2/entry#names_and_taxonomy" } ] }, { "name": "Histidine triad nucleotide-binding protein 3", "type": "synonym", "evidence": [ { "id": "A0AAA9TVW2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TVW2/entry#names_and_taxonomy" } ] } ], "function": [], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Bos taurus", "taxid": 9913, "evidence": [ { "database": "UniProtKB", "id": "A0AAA9TVW2", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TVW2" } ], "common_name": "Bovine", "glygen_name": "Bovine", "reference_species": "Bos taurus [9913]" } ], "gene": [ { "name": "HINT3", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TVW2", "locus": { "chromosome": "9", "start_pos": 25326267, "end_pos": 25340234, "strand": "+", "evidence": [ { "database": "Ensembl Gene", "id": "ENSBTAG00000001956", "url": "https://www.ensembl.org/id/ENSBTAG00000001956" } ] } } ], "crossref": [ { "id": "A0AAA9TVW2", "url": "https://alphafold.ebi.ac.uk/entry/A0AAA9TVW2", "database": "AlphaFoldDB", "categories": [] }, { "id": "cd01278", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd01278", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "IPR011146", "url": "https://www.ebi.ac.uk/interpro/entry/IPR011146", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR036265", "url": "https://www.ebi.ac.uk/interpro/entry/IPR036265", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "PTHR12486", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR12486", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR12486:SF5", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR12486:SF5", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF11969", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF11969", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "67916", "url": "https://www.rhea-db.org/rhea/67916", "database": "Rhea", "categories": [ "Enzyme and Pathway" ] }, { "id": "A0AAA9TVW2", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TVW2", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0AAA9TVW2-1", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TVW2-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0AAF6YJ97", "url": "https://www.uniprot.org/uniprotkb/A0AAF6YJ97", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0AAF6YJ97-1", "url": "https://www.uniprot.org/uniprotkb/A0AAF6YJ97-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MMEEEECGLGKSCARSEPVAAAQPAGSPGETPAVAAESPELANYSSKCVFCRIAAHQDPGTELLHCENEDLVCFKDIKPAAPHHYLVVPKKHFENCKYLKKDQIELIENMVTVGKAILERNNFTDFENTRMGFHVSPFCSIAHLHLHVLAPADQLSFMSRLVYRVNSYWFITVIRSVGRDTVVKSLNCKQRI", "length": 192, "header": "tr|A0AAA9TVW2-1|A0AAA9TVW2_BOVIN Isoform 1 of Adenosine 5'-monophosphoramidase HINT3 OS=Bos taurus OX=9913 GN=HINT3 PE=3 SV=2 CANONICAL=A0AAA9TVW2-1" }, "isoforms": [ { "isoform_ac": "A0AAA9TVW2-1", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TVW2/entry", "sequence": { "sequence": "MMEEEECGLGKSCARSEPVAAAQPAGSPGETPAVAAESPELANYSSKCVFCRIAAHQDPGTELLHCENEDLVCFKDIKPAAPHHYLVVPKKHFENCKYLKKDQIELIENMVTVGKAILERNNFTDFENTRMGFHVSPFCSIAHLHLHVLAPADQLSFMSRLVYRVNSYWFITVIRSVGRDTVVKSLNCKQRI", "length": 192, "header": "tr|A0AAA9TVW2-1|A0AAA9TVW2_BOVIN Isoform 1 of Adenosine 5'-monophosphoramidase HINT3 OS=Bos taurus OX=9913 GN=HINT3 PE=3 SV=2 CANONICAL=A0AAA9TVW2-1" }, "locus": { "chromosome": "9", "start_pos": 25339775, "end_pos": 25330770, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000127989.2", "url": "https://www.ensembl.org/id/ENSBTAT00000127989.2" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000101305.2", "url": "https://www.ensembl.org/id/ENSBTAP00000101305.2" } ] } }, { "isoform_ac": "A0AAF6YJ97-1", "url": "https://www.uniprot.org/uniprotkb/A0AAF6YJ97/entry", "sequence": { "sequence": "MMEEEECGLGKSCARSEPVAAAQPAGSPGETPAVAAESPELANYSSKCVFCRIAAHQDPGTELLHCENEDLVCFKDIKPAAPHHYLVVPKKHFENCKYLKKDQIELIENMVTVGKAILERNNFTDFENTRMGFHVSPFCSIAHLHLHVLAPADQLSFMSRLVYRVNSYWFITICYFFNYRLII", "length": 183, "header": "tr|A0AAF6YJ97-1|A0AAF6YJ97_BOVIN Computationally mapped isoform of Adenosine 5'-monophosphoramidase HINT3 OS=Bos taurus OX=9913 GN=HINT3 PE=3 SV=1 CANONICAL=A0AAA9TVW2-1" }, "locus": { "chromosome": "9", "start_pos": 25339775, "end_pos": 25326767, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000002542.6", "url": "https://www.ensembl.org/id/ENSBTAT00000002542.6" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000002542.5", "url": "https://www.ensembl.org/id/ENSBTAP00000002542.5" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [], "orthologs": [], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 2, "go_terms": [ { "name": "nucleus", "id": "GO:0005634", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005634", "evidence": [ { "database": "UniProtKB", "id": "A0AAA9TVW2", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TVW2" } ], "pmid": "" }, { "name": "cytoplasm", "id": "GO:0005737", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005737", "evidence": [ { "database": "UniProtKB", "id": "A0AAA9TVW2", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TVW2" } ], "pmid": "" } ] }, { "name": "Molecular Function", "total": 4, "go_terms": [ { "name": "identical protein binding", "id": "GO:0042802", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0042802", "evidence": [ { "database": "UniProtKB", "id": "A0AAA9TVW2", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TVW2" } ], "pmid": "" }, { "name": "nucleotide binding", "id": "GO:0000166", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000166", "evidence": [ { "database": "UniProtKB", "id": "A0AAA9TVW2", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TVW2" } ], "pmid": "" }, { "name": "adenosine 5'-monophosphoramidase activity", "id": "GO:0043530", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0043530", "evidence": [ { "database": "UniProtKB", "id": "A0AAA9TVW2", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TVW2" } ], "pmid": "" }, { "name": "hydrolase activity", "id": "GO:0016787", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016787", "evidence": [ { "database": "UniProtKB", "id": "A0AAA9TVW2", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TVW2" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 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"name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?bta:532367", "resource": "KEGG Pathway" } ], "orthologs": [], "go_annotation": {}, "pro_annotation": [], "site_annotation": [ { "start_pos": 221, "end_pos": 223, "annotation": "n_glycosylation_sequon" }, { "start_pos": 288, "end_pos": 290, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A0AAA9TVZ4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TVZ4" }, { "id": "PS50838", "database": "PROSITE", "url": "https://prosite.expasy.org/PS50838" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "MAGE", "eco_id": "ECO_0000259", "start_pos": 104, "end_pos": 302, "start_aa": "Leu", "end_aa": "Ala", "glycosite_overlap": [] } ], "binding_sites": [], "synthesized_glycans": [], 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{ "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { 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"XP_003587162", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_003587162" } ] } ], "protein_names": [ { "name": "Transcriptional protein SWT1", "type": "recommended", "evidence": [ { "id": "A0AAA9TVZ6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TVZ6/entry#names_and_taxonomy" } ] }, { "name": "LOW QUALITY PROTEIN: transcriptional protein SWT1", "type": "synonym", "evidence": [ { "id": "XP_003587162", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_003587162" } ] } ], "function": [], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Bos taurus", "taxid": 9913, "evidence": [ { "database": "UniProtKB", "id": "A0AAA9TVZ6", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TVZ6" } ], "common_name": "Bovine", "glygen_name": "Bovine", "reference_species": "Bos taurus [9913]" } ], "gene": [ { "name": "SWT1", "url": 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}, { "id": "IPR052626", "url": "https://www.ebi.ac.uk/interpro/entry/IPR052626", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "bta:506599", "url": "https://www.genome.jp/dbget-bin/www_bget?bta:506599", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "PTHR16161", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR16161", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR16161:SF0", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR16161:SF0", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF13638", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF13638", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "XP_003587162", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_003587162", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0AAA9TVZ6", "url": 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"MVAPGSVTSRLGSVFPFLLVLVDLQYEGAECGVNADVEKHLELGKKLLAAGQLADALSQFHAAVDGDPDNYIAYYRRATVFLAMGKSKAALPDLTKVIELKMDFTAARLQRGHLLLKQGKLDEAEDDFKKVVCVWDAELRELRAECFIKEGEPRKAISDLKASSKLKNDNTEAFYKISTLYYELGDHELSLSEVRECLKLDQDHKRCFAHYKQVKKLNKLIESAEELIKEGRYTDAISKYESVMKTEPGVHEYTIRSKERICHCFSKDEKPVEAIRVCSEVLQVEPDNVNALKDRAEAYLIEEMYDEAIQDYETAQEHNENDQQIREGLEKAQRLLKQSQRRDYYKILGVKRNAKKQEIIKAYRKLALQWHPDNFQNEEEKKKAEKKFIDIAAAKEVLSDPEMRKKFDDGEDPLDAESQQGGGGNPFHRSWNSWQGFNPFSSGGPFRFKFHFN", "length": 453, "header": "tr|A0A3Q1MFB6-1|A0AAA9TU35_BOVIN Computationally mapped isoform of DnaJ homolog subfamily C member 3 OS=Bos taurus OX=9913 GN=DNAJC3 PE=4 SV=2 CANONICAL=A0AAA9TU35-1" }, "locus": { "chromosome": "12", "start_pos": 73160514, "end_pos": 73095513, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000072001.3", "url": "https://www.ensembl.org/id/ENSBTAT00000072001.3" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000067615.2", "url": "https://www.ensembl.org/id/ENSBTAP00000067615.2" } ] } }, { "isoform_ac": "A0AAA9TIR3-1", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TIR3/entry", "sequence": { "sequence": "MVAPGSVTSRLGSVFPFLLVLVDLQYEGAECGVNADVEKHLELGKKLLAAGQLADALSQFHAAVDGDPDNYIAYYRRATVFLAMGKSKAALPDLTKVIELKMDFTAARLQRGHLLLKQGKLDEAEDDFKKVLKSNPSENEEKEAQSQLVKSDEMQRLRSQALDAFESSDFTAAITFLDKILEVCVWDAELRELRAECFIKEGEPRKAISDLKASSKLKNDNTEAFYKISTLYYELGDHELSLSEVRECLKLDQDHKRCFAHYKQVKKLNKLIESAEELIKEGRYTDAISKYESVMKTEPGVHEYTIRSKERICHCFSKDEKPVEAIRVCSEVLQVEPDNVNALKDRAEAYLIEEMYDEAIQDYETAQEHNENDQQIREGLEKAQRLLKQSQRRDYYKILGVKRNAKKQEIIKAYRKLALQWHPDNFQNEEEKKKAEKKFIDIAAAKEVLSDPDTDAYERLCPLSLCSAGQAAMSSWRASGSEF", "length": 483, "header": "tr|A0AAA9TIR3-1|A0AAA9TU35_BOVIN Computationally mapped isoform of DnaJ homolog subfamily C member 3 OS=Bos taurus OX=9913 GN=DNAJC3 PE=4 SV=1 CANONICAL=A0AAA9TU35-1" }, "locus": { "chromosome": "12", "start_pos": 73159703, "end_pos": 73095513, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000097228.2", "url": "https://www.ensembl.org/id/ENSBTAT00000097228.2" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000096124.1", "url": "https://www.ensembl.org/id/ENSBTAP00000096124.1" } ] } }, { "isoform_ac": "A0AAA9TU35-1", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TU35/entry", "sequence": { "sequence": "MVAPGSVTSRLGSVFPFLLVLVDLQYEGAECGVNADVEKHLELGKKLLAAGQLADALSQFHAAVDGDPDNYIAYYRRATVFLAMGKSKAALPDLTKVIELKMDFTAARLQRGHLLLKQGKLDEAEDDFKKVLKSNPSENEEKEAQSQLVKSDEMQRLRSQALDAFESSDFTAAITFLDKILEVCVWDAELRELRAECFIKEGEPRKAISDLKASSKLKNDNTEAFYKISTLYYELGDHELSLSEVRECLKLDQDHKRCFAHYKQVKKLNKLIESAEELIKEGRYTDAISKYESVMKTEPGVHEYTIRSKERICHCFSKDEKPVEAIRVCSEVLQVEPDNVNALKDRAEAYLIEEMYDEAIQDYETAQEHNENDQQIREGLEKAQRLLKQSQRRDYYKILGVKRNAKKQEIIKAYRKLALQWHPDNFQNEEEKKKAEKKFIDIAAAKEVLSDPEMRKKFDDGEDPLDAESQQGGGGNPFHRSWNSWQGFNPFSSGGPFRFKFHFN", "length": 504, "header": "tr|A0AAA9TU35-1|A0AAA9TU35_BOVIN Isoform 1 of DnaJ homolog subfamily C member 3 OS=Bos taurus OX=9913 GN=DNAJC3 PE=4 SV=2 CANONICAL=A0AAA9TU35-1" }, "locus": { "chromosome": "12", "start_pos": 73160514, "end_pos": 73095513, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000118901.2", "url": "https://www.ensembl.org/id/ENSBTAT00000118901.2" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000100606.2", "url": "https://www.ensembl.org/id/ENSBTAP00000100606.2" } ] } }, { "isoform_ac": "F1N036-1", "url": "https://www.uniprot.org/uniprotkb/F1N036/entry", "sequence": { "sequence": "MVAPGSVTSRLGSVFPFLLVLVDLQYEGAECGVNADVEKHLELGKKLLAAGQLADALSQFHAAVDGDPDNYIAYYRRATVFLAMGKSKAALPDLTKVIELKMDFTAARLQRGHLLLKQGKLDEAEDDFKKVLKSNPSENEEKEAQSQLVKSDEMQRLRSQALDAFESSDFTAAITFLDKILEVCVWDAELRELRAECFIKEGEPRKAISDLKASSKLKNDNTEAFYKISTLYYELGDHELSLSEVRECLKLDQDHKRCFAHYKQVKKLNKLIESAEELIKEGRYTDAISKYESVMKTEPGVHEYTIRSKERICHCFSKDEKPVEAIRVCSEVLQVEPDNVNALKDRAEAYLIEEMYDEAIQDYETAQEHNENDQQIREGLEKAQRLLKQSQRRDYYKILGVKRNAKKQEIIKAYRKLALQWHPDNFQNEEEKKKAEKKFIDIAAAKEVLSDPGKNFLGWLLRRFQGSEFRNEEEV", "length": 475, "header": "tr|F1N036-1|F1N036_BOVIN Computationally mapped isoform of DnaJ homolog subfamily C member 3 OS=Bos taurus OX=9913 GN=DNAJC3 PE=4 SV=2 CANONICAL=A0AAA9TU35-1" }, "locus": { "chromosome": "12", "start_pos": 73160375, "end_pos": 73095513, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000016001.8", "url": "https://www.ensembl.org/id/ENSBTAT00000016001.8" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000016001.6", "url": "https://www.ensembl.org/id/ENSBTAP00000016001.6" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [ { "id": "R-BTA-381426", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-BTA-381426", "resource": "Reactome", "description": "Regulation of Insulin-like Growth Factor (IGF) transport and uptake by Insulin-like Growth Factor Binding Proteins (IGFBPs)" }, { "id": "R-BTA-6798695", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-BTA-6798695", "resource": "Reactome", "description": "Neutrophil degranulation" }, { "id": "R-BTA-8957275", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-BTA-8957275", "resource": "Reactome", "description": "Post-translational protein phosphorylation" }, { "id": "R-BTA-9833482", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-BTA-9833482", "resource": "Reactome", "description": "PKR-mediated signaling" } ], "orthologs": [ { "uniprot_canonical_ac": "F1P053-1", "protein_name": "DnaJ homolog subfamily C member 3", "gene_name": "DNAJC3", "tax_id": 9031, "organism": "Gallus gallus", "sequence": { "sequence": "MVSAAASAGRLGSALPFLLVLLDLQYQGAECGINAEVEKQLEMGKKLLAAGQLADALSHFHAAIEGDSDNYIAYYRRATVYLAMGKSKAAIRDLSKVVELKQDFTSARLQRGHLLLKQGKFDEAEDDFKNVLKSNPSNNEEKEAQTQLTKSDELQRLYSQALSAYRQEDYEAAIPLLDEILAVCVWDAELRELRAECYIKEGEPSKAISDLKAAAKLKSDNTEAFYKISRIYYQLGDHELSLSEVRECLKLDQDHKQCFSLYKQVKKLNKQIESAEEFIREGRYEDAISKYDSVMKTEPDVPVYATRAKERICHCLSKNQQATEAITVCTQVLQLEPTNVNALKDRAEAYLLEDLYEEAIKDYETAQANSENDQQIREGLERAQRMLKQSQKRDYYKILGVKRNARKQEIIKAYRKLASQWHPDNFQSEEEKKKAEKKFIDIAAAKEVLTDPEMRRKFDAGEDPLDAESQQGGGNPFHRNWNTWQGFNPFGSGGGPFTFKFHFS", "length": 504 }, "evidence": [ { "id": "A0AAA9TU35", "url": "https://omabrowser.org/oma/group/A0AAA9TU35/", "database": "OMA" } ], "glygen_name": "Chicken", "common_name": "Chicken" }, { "uniprot_canonical_ac": "I3LBK9-1", "protein_name": "DnaJ homolog subfamily C member 3", "gene_name": "DNAJC3", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MVAPGSVTSRLGSVFPFLLVLVDLQYEGAECGVNADVEKHLELGKKLLAAGQLADALSQFHAAVDGDPDNYIAYYRRATVFLAMGKSKALPDLTKVIELKMDFTAARLQRGHLLLKQGKLDEAEDDFKKVLKSNPSENEEKEAQSQLIKSDEMQRLRSQALDAFESSDYTAAITFLDKILEVCVWDAELRELRAECFIKEGEPRKAISDLKAASKLKNDNTEAFYKISTLYYQLGDHELSLSEVRECLKLDQDHKRCFAHYKQVKKLNKLIESAEELIRDGRYTDATSKYESVMKTEPNVAEYTIRSKERICHCFSKDEKPVEAIRVCSEVLQVEPDNVNALKDRAEAYLVEEMYDEAIQDYETAQEHNENDQQIREGLEKAQRLLKQSQKRDYYKILGVKRNAKKQEIIKAYRKLALQWHPDNFQNEEEKKKAEKKFIDIAAAKEVLSDPEMRKKFDDGEDPLDAESQQGGGGGSPFHRSWNSWQGFNPFSSGGPFRFKFHFN", "length": 504 }, "evidence": [ { "id": "A0AAA9TU35", "url": "https://omabrowser.org/oma/group/A0AAA9TU35/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "Q13217-1", "protein_name": "DnaJ homolog subfamily C member 3", "gene_name": "DNAJC3", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MVAPGSVTSRLGSVFPFLLVLVDLQYEGAECGVNADVEKHLELGKKLLAAGQLADALSQFHAAVDGDPDNYIAYYRRATVFLAMGKSKAALPDLTKVIQLKMDFTAARLQRGHLLLKQGKLDEAEDDFKKVLKSNPSENEEKEAQSQLIKSDEMQRLRSQALNAFGSGDYTAAIAFLDKILEVCVWDAELRELRAECFIKEGEPRKAISDLKAASKLKNDNTEAFYKISTLYYQLGDHELSLSEVRECLKLDQDHKRCFAHYKQVKKLNKLIESAEELIRDGRYTDATSKYESVMKTEPSIAEYTVRSKERICHCFSKDEKPVEAIRVCSEVLQMEPDNVNALKDRAEAYLIEEMYDEAIQDYETAQEHNENDQQIREGLEKAQRLLKQSQKRDYYKILGVKRNAKKQEIIKAYRKLALQWHPDNFQNEEEKKKAEKKFIDIAAAKEVLSDPEMRKKFDDGEDPLDAESQQGGGGNPFHRSWNSWQGFNPFSSGGPFRFKFHFN", "length": 504 }, "evidence": [ { "id": "A0AAA9TU35", "url": "https://omabrowser.org/oma/group/A0AAA9TU35/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "Q54M21-1", "protein_name": "DnaJ homolog subfamily C member 3 homolog", "gene_name": "dnajc3", "tax_id": 44689, "organism": "Dictyostelium discoideum", "sequence": { "sequence": "MIVNKKYFLLICIIILISINCLVLAKDEIENFLKEGDDLVSKGKYDLANENYSNAIDLIGSDTQHPQYVSLLFKRAGIYHQKGKNILALSDLNRAIEANPDNIHARLKRAKIQSSLGRFEEAMDEYKRVLKIRPDNSQAKQQIEKLKKVEQQLEKVRDMVKVEKNYKDSIAILLDIQSVVSDLKEVRLMLCECFFQQGDHRKVLDETMTILKSEPSSVAALYWRGKTFFSMGEKEIAMKFLKEGLKFDPDNTNCRAMIKTINKFEKSTANAQELFNQQKYQDALGQIEDALEIEPNSPTHSTPLYLLKCKCLLKVKKGKESIEACNRALELDELNADALYNRAEAYMYEEDYQKALNDYNKAREHKPNDPQIHDGIRRAQKAQQMAKRKDYYKILGIQKSATPEEIKKAFKKLAIKNHPDKSTETDKEKAQQIYMDINEAYEALKDEEKRKRYDMGEDINDPHGGQGGQGGGFGGFGGFHGFQGFQGFQQGGGGGGFQFHFR", "length": 502 }, "evidence": [ { "id": "A0AAA9TU35", "url": "https://omabrowser.org/oma/group/A0AAA9TU35/", "database": "OMA" } ], "glygen_name": "Cellular slime mold", "common_name": "Social amoeba" }, { "uniprot_canonical_ac": "Q91YW3-1", "protein_name": "DnaJ homolog subfamily C member 3", "gene_name": "Dnajc3", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MVAPGSVGSRLGAVFPFLLVLVDLQYEGAECGVNADVEKHLELGKKLLAAGQLADALSQFHAAVDGDPDNYIAYYRRATVFLAMGKSKAALPDLTKVIALKMDFTAARLQRGHLLLKQGKLDEAEDDFKKVLKSNPSEQEEKEAESQLVKADEMQRLRSQALDAFDGADYTAAITFLDKILEVCVWDAELRELRAECFIKEGEPRKAISDLKAASKLKSDNTEAFYKISTLYYQLGDHELSLSEVRECLKLDQDHKRCFAHYKQVKKLNKLIESAEELIRDGRYTDATSKYESVMKTEPSVAEYTVRSKERICHCFSKDEKPVEAIRICSEVLQMEPDNVNALKDRAEAYLIEEMYDEAIQDYEAAQEHNENDQQIREGLEKAQRLLKQSQKRDYYKILGVKRNAKKQEIIKAYRKLALQWHPDNFQNEEEKKKAEKKFIDIAAAKEVLSDPEMRKKFDDGEDPLDAESQQGGGGNPFHRSWNSWQGFNPFSSGGPFRFKFHFN", "length": 504 }, "evidence": [ { "id": "A0AAA9TU35", "url": "https://omabrowser.org/oma/group/A0AAA9TU35/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q9LYW9-1", "protein_name": "DnaJ protein P58IPK homolog", "gene_name": "P58IPK", "tax_id": 3702, "organism": "Arabidopsis thaliana", "sequence": { "sequence": "MDLFRVWSGMDFLAWRGMAYTLLLLNFVFACQLLLLQPLVSALDGQSVDAAELFERASQSIKVKRYSDALDDLNAAIEADPALSEAYFKRASVLRHFCRYEDSENSYQKYLEFKSGDSNAEKELSQLHQAKSALETASTLYESKDIAKALEFVDKVVLVFSPACSKAKLLKVKLLMVSKDYSGAISETGYILKEDENNLEALLLRGRAYYYLADHDIAQRHYQKGLRLDPEHSELKKAYFGLKKLLKKTKSAEDNANKGKLRVSAEEYKEAIALDPEHTANNVHLYLGLCKVSVRLGRGKDGLNSCNEALNIDAELIEALHQRGEAKLLLEDWEGAVEDLKQAAQNSQDMEIHESLGKAEKALKMSKRKDWYKILGISRTASISEIKKAYKKLALQWHPDKNVGNREEAENKFREIAAAYEILGDDDKRARFDRGEDLEDMGGGGGGGYNPFHGGGGGGQQYTFHFEGGFPGGGGGFGGFGF", "length": 482 }, "evidence": [ { "id": "A0AAA9TU35", "url": "https://omabrowser.org/oma/group/A0AAA9TU35/", "database": "OMA" } ], "glygen_name": "Arabidopsis", "common_name": "Mouse-ear cress" }, { "uniprot_canonical_ac": "Q9R0T3-1", "protein_name": "DnaJ homolog subfamily C member 3", "gene_name": "Dnajc3", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MVAPGSVRSRLGAVFPFLLVLVDLQYEGAECGVNADVEKHLELGKKLLAAGQLADALSQFHAAVDGDPDNYIAYYRRATVFLAMGKSKAALPDLTRVIELKMDFTAARLQRGHLLLKQGRLAEAEDDFKKVLKSNPSENEEKEAQSQLVKADEMQRLRAQALDAFDSADYTAAITFLDEILEVCVWDAELRELRAECFIKEGEPRKAISDLKAASKLKNDNTEAFYKISILYYQLGDHELSLSEVRECLKLDQDHKRCFAHYKQVKKLNKLIGSAEELIRDGRYTDATSKYESVMKAEPSVAEYTVRSKERICHCFSKDEKPVEAIKICSEVLQLEPDNVNALKDRAEAYLIEEMYDEAIQDYEAAQEQNENDQQIREGLEKAQRLLKQSQKRDYYKILGVKRNAKKQEIIKAYRKLALQWHPDNFQSEEEKKKAEKKFIDIAAAKEVLSDPEMRRKFDDGEDPLDAETQQGGGSNPFHRSWDSWQGFNPFSSGGPFRFKFHFN", "length": 504 }, "evidence": [ { "id": "A0AAA9TU35", "url": "https://omabrowser.org/oma/group/A0AAA9TU35/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "Q9VHA8-1", "protein_name": "P58IPK", "gene_name": "P58IPK", "tax_id": 7227, "organism": "Drosophila melanogaster", "sequence": { "sequence": "MALPLSDLLMIGGGEKKLAACLVLLLLELFLEGAESTASPADIENHLELGKEFLARGQLSDALTHYHAAVEGDANNYLTLFKRGTVYLALGKTRFAVQDFSRVLELKPDFMAARIQRGVVHMKSGEYEQAIQDFDQVLQEEPNNGLVLEHYSRLAPAQEQWVLVQQLIQYSDHQNAIPMITQLLEISPWAVPFRQARSDAYIAINDPLLAIADLRQVNRLTQDSTEGHYKIAQLLYTIGHATNALKEIRECLKFDPEHKLCFPFYKKLRKVEKQLVNAEQAREEKHFAECIAAGEAVLRNEPEETMIRYEGHKVLCTCYTGDEQFGKALQQCKEALDIMKDAQVYCDRADALLGTEMYDDAIHSFQAALDLEESNTRAKEGIQRAKKLQKQSERRDYYKILGVKRSASKQEIVKAYRKAAQKWHPDNFRDEEKKVAEKKFIDIAAAKEVLTDPEKRRQFDNGEDPLDPESNQRGGFHGEHPFGHFQHGSPFQFKFHFN", "length": 498 }, "evidence": [ { "id": "A0AAA9TU35", "url": "https://omabrowser.org/oma/group/A0AAA9TU35/", "database": "OMA" } ], "glygen_name": "Fruit fly", "common_name": "Fruit fly" } ], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 3, "go_terms": [ { "name": "endoplasmic reticulum", "id": "GO:0005783", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005783", "evidence": [ { "database": "UniProtKB", "id": "A0AAA9TU35", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TU35" } ], "pmid": "" }, { "name": "endoplasmic reticulum lumen", "id": "GO:0005788", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005788", "evidence": [ { "database": "UniProtKB", "id": "A0AAA9TU35", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TU35" } ], "pmid": "" }, { "name": "cytosol", "id": "GO:0005829", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005829", "evidence": [ { "database": "UniProtKB", "id": "A0AAA9TU35", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TU35" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 7, "go_terms": [ { "name": "response to unfolded protein", "id": "GO:0006986", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006986", "evidence": [ { "database": "UniProtKB", "id": "A0AAA9TU35", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TU35" } ], "pmid": "" }, { "name": "positive regulation of translation initiation in response to endoplasmic reticulum stress", "id": "GO:0036494", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0036494", "evidence": [ { "database": "UniProtKB", "id": "A0AAA9TU35", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TU35" } ], "pmid": "" }, { "name": "cellular response to cold", "id": "GO:0070417", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0070417", "evidence": [ { "database": "UniProtKB", "id": "A0AAA9TU35", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TU35" } ], "pmid": "" }, { "name": "negative regulation of apoptotic process", "id": "GO:0043066", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0043066", "evidence": [ { "database": "UniProtKB", "id": "A0AAA9TU35", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TU35" } ], "pmid": "" }, { "name": "proteolysis involved in protein catabolic process", "id": "GO:0051603", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0051603", "evidence": [ { "database": "UniProtKB", "id": "A0AAA9TU35", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TU35" } ], "pmid": "" }, { "name": "negative regulation of translation in response to endoplasmic reticulum stress", "id": "GO:1902010", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:1902010", "evidence": [ { "database": "UniProtKB", "id": "A0AAA9TU35", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TU35" } ], "pmid": "" }, { "name": "protein folding in endoplasmic reticulum", "id": "GO:0034975", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0034975", "evidence": [ { "database": "UniProtKB", "id": "A0AAA9TU35", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TU35" } ], "pmid": "" } ] }, { "name": "Molecular Function", "total": 4, "go_terms": [ { "name": "protein kinase binding", "id": "GO:0019901", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0019901", "evidence": [ { "database": "UniProtKB", "id": "A0AAA9TU35", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TU35" } ], "pmid": "" }, { "name": "protein-folding chaperone binding", "id": "GO:0051087", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0051087", "evidence": [ { "database": "UniProtKB", "id": "A0AAA9TU35", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TU35" } ], "pmid": "" }, { "name": "protein kinase inhibitor activity", "id": "GO:0004860", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0004860", "evidence": [ { "database": "UniProtKB", "id": "A0AAA9TU35", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TU35" } ], "pmid": "" }, { "name": "misfolded protein binding", "id": "GO:0051787", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0051787", "evidence": [ { "database": "UniProtKB", "id": "A0AAA9TU35", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TU35" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A0AAA9TU35", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TU35" }, { "id": "PS50076", "database": "PROSITE", "url": "https://prosite.expasy.org/PS50076" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "J", "eco_id": "ECO_0000259", "start_pos": 394, "end_pos": 462, "start_aa": "Asp", "end_aa": "Glu", "glycosite_overlap": [] } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" }, { "name": "homologset.oma", "label": "OMA Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": 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"length": 1035, "header": "tr|A0A3Q1NCI2-1|A0AAA9TSI5_BOVIN Computationally mapped isoform of Integrin subunit alpha M OS=Bos taurus OX=9913 GN=ITGAM PE=1 SV=1 CANONICAL=A0AAA9TSI5-1" }, "locus": { "chromosome": "25", "start_pos": 27381710, "end_pos": 27344111, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000076414.3", "url": "https://www.ensembl.org/id/ENSBTAT00000076414.3" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000069105.1", "url": "https://www.ensembl.org/id/ENSBTAP00000069105.1" } ] } }, { "isoform_ac": "A0AAA9TSI5-1", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TSI5/entry", "sequence": { "sequence": "MNHRILLLTALALCHGFNLDTEKAVIFQNNARGFGQSVVQIQGSRLVVGAPQEVKAANQTGGLYHCDYSTGRCEAIPLQVPPEAVNMSLGLSLAFAANPFRLLACGPTVHQICKENTYANGLCFSFGSNLLQQPRRIPRALRGCPEQDSDIAFLIDGSGSIDPVDFERMKRFVSTVMSQFQKSKTLFSLMQYSDDFQTHFTFNDFKRNPVPEFLVGPIRQLFGRTHTATGIRKVVRELFHSSSGARNHAIKIMIVITDGEKYLDPLEYSDVIPEADRKKIIRYVIGVGDAFRSRKSRQELDTIASKPPADHVFQVNNFEALKTIQNQLQEKIFAIEGTQTGSTSSFEHEMSQEGFSAAFTSDGPLLGAVGSFDWAGGAFLHTSNDKITFINTTRIDSDMNDAYLGYAAEVTLRNRVQHLFLGAPRYQHIGLVVIFRQNAGVWQKNAEIKGSQIGSYFGASLCSVDVNRDGSSDLVLIGAPHFYEQMRGGQVSMCPFPRGRAKWQCDAVLRGEPGHPWGRFGAALTALGDVNGDRLVDVAIGAPGEQENQGAVYLFHGTSKLGISPSHSQRITGSQISPKLQYFGQSLSGGQDLTMDGLVDLAVGAQGHVLLLRSQPVLKVEATMEFTPKEVKRNVYECRDPVVKGQIAGQVKVCLQVRKSTWDRLGEGDTQSTITYDLALDPGRPHSVAIFDETQNSTRRRVETLRLSQKCETLKLRLLDCVEDSVTPIALRLNFSLVGEPAHNYGGLRPVLAVDALRLFTASLPFEKNCGNDTVCQDDLSITFSFMDLDTLVVGGPRDLNVTVTVRNEGEDSYRTQVTFFYPSGLSYRRVSSSQNQRSQRFWRLTCESDVSTEGSGILKRTSCGINHPIFLDNSEITFNVTFDVNPDTYFGNKLLLKANVTSENNMPGNNKTQFQLELPVKYAVYMVVTSLEASTKYLNFTASEKTVHAMEHQYQFNNLGRKKLPISVVFWIPIRLNKVPVWSQPQVTFSQDVSSGCNTTEVAPRHSDFLAELKKSPVLNCSVAVCQRIQCAIPSFGIQEEFKVTLKSNFSFDWYIKTSHNHLQVVSKAEILFDESKFTLLPGQDAFVMAQTGTKVESYEVHNPIPLIVGSSVGGLVLLALISAGLYKLGFFKRQYKDMMTEPGPEVDTPQ", "length": 1152, "header": "tr|A0AAA9TSI5-1|A0AAA9TSI5_BOVIN Isoform 1 of Integrin subunit alpha M OS=Bos taurus OX=9913 GN=ITGAM PE=1 SV=2 CANONICAL=A0AAA9TSI5-1" }, "locus": { "chromosome": "25", "start_pos": 27381710, "end_pos": 27344111, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000117982.2", "url": "https://www.ensembl.org/id/ENSBTAT00000117982.2" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000100315.2", "url": "https://www.ensembl.org/id/ENSBTAP00000100315.2" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [], "orthologs": [], "go_annotation": { "categories": [ { "name": "Biological Process", "total": 8, "go_terms": [ { "name": "cell adhesion", "id": "GO:0007155", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007155", "evidence": [ { "database": "UniProtKB", "id": "A0AAA9TSI5", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TSI5" } ], "pmid": "" }, { "name": "integrin-mediated signaling pathway", "id": "GO:0007229", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007229", "evidence": [ { "database": "UniProtKB", "id": "A0AAA9TSI5", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TSI5" } ], "pmid": "" }, { "name": "positive regulation of superoxide anion generation", "id": "GO:0032930", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0032930", "evidence": [ { "database": "UniProtKB", "id": "A0AAA9TSI5", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TSI5" } ], "pmid": "" }, { "name": "cell-matrix adhesion", "id": "GO:0007160", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007160", "evidence": [ { "database": "UniProtKB", "id": "A0AAA9TSI5", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TSI5" } ], "pmid": "" }, { "name": "cell-cell adhesion mediated by integrin", "id": "GO:0033631", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0033631", "evidence": [ { "database": "UniProtKB", "id": "A0AAA9TSI5", "url": 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"Protein" ] }, { "id": "F6QYA3", "url": "https://www.uniprot.org/uniprotkb/F6QYA3", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "F6QYA3-1", "url": "https://www.uniprot.org/uniprotkb/F6QYA3-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MIFLTALSLFWIMISASRGGQWGAWMPSSISAFEGTCVSIPCRFSFPDELRPAVVHGVWYFNSPYPKNYPPVVFKSRTQVVHESFQGRSRLLGDLGLRNCTLLLSNLSPELGGKYYFRGDLGGYNQYTFSEHSVLDIINTPNIVVPPEVMAGTEVEVSCMVPDNCPELHPELSWLGHEGLGEPTVLGRLREEEGTWVQVSLLHFVPTRETNGHRLGCQASFPNTTLQFEGYASLDIKYPPVIVEINSTVEAIEGSHVSLFCGADSNPPPLLTWMRDGTVLREAVAESLSLEVDEVTPAEDGVYLCLAENTYGQDNRTVELSVMYAPWKPMVNGTVVAVEGETVSILCSTQSNPDPILTIFKEKQILATVIYESELQLELPAVTPEDDGEYWCVAENQYGQRATAFNLSVEFAPVILLESHCAAARDTVQCLCVVKANPEPSVAFELPLRNVTVNETEREFVYSERSGLLLTSILTLRGQAQAPPRVICTSHNLYGTKSLELPFQGAHRLMWAKIGPVGAVVAFAILIAIVCYITQTRRKKNVTESPSFSGGDNPPVVFSSDFRISGAPEKYESERRLGSERRLLGLRGEPPELDLSYSHSDLGKRPTKDSYTLTEELAEYAEIRVK", "length": 626, "header": "tr|A0AAA9TU91-1|A0AAA9TU91_BOVIN Isoform 1 of Myelin-associated glycoprotein OS=Bos taurus OX=9913 GN=MAG PE=3 SV=2 CANONICAL=A0AAA9TU91-1" }, "isoforms": [ { "isoform_ac": "A0AAA9TU91-1", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TU91/entry", "sequence": { "sequence": "MIFLTALSLFWIMISASRGGQWGAWMPSSISAFEGTCVSIPCRFSFPDELRPAVVHGVWYFNSPYPKNYPPVVFKSRTQVVHESFQGRSRLLGDLGLRNCTLLLSNLSPELGGKYYFRGDLGGYNQYTFSEHSVLDIINTPNIVVPPEVMAGTEVEVSCMVPDNCPELHPELSWLGHEGLGEPTVLGRLREEEGTWVQVSLLHFVPTRETNGHRLGCQASFPNTTLQFEGYASLDIKYPPVIVEINSTVEAIEGSHVSLFCGADSNPPPLLTWMRDGTVLREAVAESLSLEVDEVTPAEDGVYLCLAENTYGQDNRTVELSVMYAPWKPMVNGTVVAVEGETVSILCSTQSNPDPILTIFKEKQILATVIYESELQLELPAVTPEDDGEYWCVAENQYGQRATAFNLSVEFAPVILLESHCAAARDTVQCLCVVKANPEPSVAFELPLRNVTVNETEREFVYSERSGLLLTSILTLRGQAQAPPRVICTSHNLYGTKSLELPFQGAHRLMWAKIGPVGAVVAFAILIAIVCYITQTRRKKNVTESPSFSGGDNPPVVFSSDFRISGAPEKYESERRLGSERRLLGLRGEPPELDLSYSHSDLGKRPTKDSYTLTEELAEYAEIRVK", "length": 626, "header": "tr|A0AAA9TU91-1|A0AAA9TU91_BOVIN Isoform 1 of Myelin-associated glycoprotein OS=Bos taurus OX=9913 GN=MAG PE=3 SV=2 CANONICAL=A0AAA9TU91-1" }, "locus": { "chromosome": "18", "start_pos": 46018536, "end_pos": 46004683, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000126017.2", "url": "https://www.ensembl.org/id/ENSBTAT00000126017.2" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000102174.2", "url": "https://www.ensembl.org/id/ENSBTAP00000102174.2" } ] } }, { "isoform_ac": "F6QYA3-1", "url": "https://www.uniprot.org/uniprotkb/F6QYA3/entry", "sequence": { "sequence": "MIFLTALSLFWIMISASRGGQWGAWMPSSISAFEGTCVSIPCRFSFPDELRPAVVHGVWYFNSPYPKNYPPVVFKSRTQVVHESFQGRSRLLGDLGLRNCTLLLSNLSPELGGKYYFRGDLGGYNQYTFSEHSVLDIINTPNIVVPPEVMAGTEVEVSCMVPDNCPELHPELSWLGHEGLGEPTVLGRLREEEGTWVQVSLLHFVPTRETNGHRLGCQASFPNTTLQFEGYASLDIKYPPVIVEINSTVEAIEGSHVSLFCGADSNPPPLLTWMRDGTVLREAVAESLSLEVDEVTPAEDGVYLCLAENTYGQDNRTVELSVMYAPWKPMVNGTVVAVEGETVSILCSTQSNPDPILTIFKEKQILATVIYESELQLELPAVTPEDDGEYWCVAENQYGQRATAFNLSVEFAPVILLESHCAAARDTVQCLCVVKANPEPSVAFELPLRNVTVNETEREFVYSERSGLLLTSILTLRGQAQAPPRVICTSHNLYGTKSLELPFQGAHRLMWAKIGPVGAVVAFAILIAIVCYITQTRRKKNVTESPSFSGGDNPPVVFSSDFRISGAPEKYESREVSTLE", "length": 580, "header": "tr|F6QYA3-1|F6QYA3_BOVIN Computationally mapped isoform of Myelin-associated glycoprotein OS=Bos taurus OX=9913 GN=MAG PE=3 SV=3 CANONICAL=A0AAA9TU91-1" }, "locus": { "chromosome": "18", "start_pos": 46017694, "end_pos": 46004683, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000056677.5", "url": "https://www.ensembl.org/id/ENSBTAT00000056677.5" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000049802.4", "url": "https://www.ensembl.org/id/ENSBTAP00000049802.4" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [ { "id": "bta:540576", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?bta:540576", "resource": "KEGG Pathway" }, { "id": "R-BTA-193634", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-BTA-193634", "resource": "Reactome", "description": "Axonal growth inhibition (RHOA activation)" } ], "orthologs": [ { "uniprot_canonical_ac": "F1QSA4-1", "protein_name": "Myelin-associated glycoprotein isoform 1 precursor", "gene_name": "mag", "tax_id": 7955, "organism": "Danio rerio", "sequence": { "sequence": "MKGLELLLLPLLLLLKDASAQWNVWMPRDISAMTNSCVVIPCSFTYPSGIRPYRGVHGIWYFGHPYPQLFPPVVLKSRTDIVHESYKGRTKLLGDLTQKNCTLLISNIGVEHSGKYYFRADLGGANIYTFPDFTKLQVLDQPNIDVPEEIVSDQSLDLTCYVPDNCPDMSPEIHWMYTDYLPDPVFTPDQVEEGNTAVLSSTLTFTPKPMHNGQLLGCRVNFPNTTYVYERLITLDIRYAPRTVWVNVSQEVMEGSSVVLHCDVDSNPAPMITWYFGDKELMSETASNSSLSLENLTPEQEGVYTCVGDNGYGNMNTSMYLAVNYPPREPWINESLTVLEGSSVSLQCTSKGNPMPTLTWLKDGELVGTITAEEGSVLELHEIMPQADGVYRCLAENEHGRASSSLNITVEFAPVLLDDSKCTIVREGVQCVCIASGNPEPAIEFYLPDLNVTINNSNNRFNYYTHSDGYTSTGVIKLQDKGERGNNGDTAVHVHCSITNIYGSETIRLELQQEKKYMMAVIVGTIGGVAVIAFIIAAVRYVGQNNKKENGNPGQDVGSKVENPSMFYSAVKKDKQSLRKKVLKTELLGSKFNSILEEGTGDDSDYQSVGPMAGMERQELNYAALEFLHGRHREGVFRRADGDGSDYTEIKAK", "length": 653 }, "evidence": [ { "id": "A0AAA9TU91", "url": "https://omabrowser.org/oma/group/A0AAA9TU91/", "database": "OMA" } ], "glygen_name": "Zebrafish", "common_name": "Zebrafish" }, { "uniprot_canonical_ac": "P07722-1", "protein_name": "Myelin-associated glycoprotein", "gene_name": "Mag", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MIFLTTLPLFWIMISASRGGHWGAWMPSSISAFEGTCVSIPCRFDFPDELRPAVVHGVWYFNSPYPKNYPPVVFKSRTQVVHESFQGRSRLLGDLGLRNCTLLLSTLSPELGGKYYFRGDLGGYNQYTFSEHSVLDIINTPNIVVPPEVVAGTEVEVSCMVPDNCPELRPELSWLGHEGLGEPTVLGRLREDEGTWVQVSLLHFVPTREANGHRLGCQAAFPNTTLQFEGYASLDVKYPPVIVEMNSSVEAIEGSHVSLLCGADSNPPPLLTWMRDGMVLREAVAESLYLDLEEVTPAEDGIYACLAENAYGQDNRTVELSVMYAPWKPTVNGTVVAVEGETVSILCSTQSNPDPILTIFKEKQILATVIYESQLQLELPAVTPEDDGEYWCVAENQYGQRATAFNLSVEFAPIILLESHCAAARDTVQCLCVVKSNPEPSVAFELPSRNVTVNETEREFVYSERSGLLLTSILTLRGQAQAPPRVICTSRNLYGTQSLELPFQGAHRLMWAKIGPVGAVVAFAILIAIVCYITQTRRKKNVTESPSFSAGDNPHVLYSPEFRISGAPDKYESEKRLGSERRLLGLRGEPPELDLSYSHSDLGKRPTKDSYTLTEELAEYAEIRVK", "length": 626 }, "evidence": [ { "id": "A0AAA9TU91", "url": "https://omabrowser.org/oma/group/A0AAA9TU91/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "P20916-1", "protein_name": "Myelin-associated glycoprotein", "gene_name": "MAG", "tax_id": 9606, "organism": "Homo sapiens", 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"sequence": { "sequence": "MIFLATLPLFWIMISASRGGHWGAWMPSTISAFEGTCVSIPCRFDFPDELRPAVVHGVWYFNSPYPKNYPPVVFKSRTQVVHESFQGRSRLLGDLGLRNCTLLLSTLSPELGGKYYFRGDLGGYNQYTFSEHSVLDIVNTPNIVVPPEVVAGTEVEVSCMVPDNCPELRPELSWLGHEGLGEPTVLGRLREDEGTWVQVSLLHFVPTREANGHRLGCQAAFPNTTLQFEGYASLDVKYPPVIVEMNSSVEAIEGSHVSLLCGADSNPPPLLTWMRDGMVLREAVAKSLYLDLEEVTPGEDGVYACLAENAYGQDNRTVELSVMYAPWKPTVNGTVVAVEGETVSILCSTQSNPDPILTIFKEKQILATVIYESQLQLELPAVTPEDDGEYWCVAENQYGQRATAFNLSVEFAPIILLESHCAAARDTVQCLCVVKSNPEPSVAFELPSRNVTVNETEREFVYSERSGLLLTSILTIRGQAQAPPRVICTSRNLYGTQSLELPFQGAHRLMWAKIGPVGAVVAFAILIAIVCYITQTRRKKNVTESSSFSGGDNPHVLYSPEFRISGAPDKYESEKQRLGSERRLLGLRGESPELDLSYSHSDLGKRPTKDSYTLTEELAEYAEIRVK", "length": 627 }, "evidence": [ { "id": "A0AAA9TU91", "url": "https://omabrowser.org/oma/group/A0AAA9TU91/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" } ], "go_annotation": { "categories": [ { "name": "Biological Process", "total": 5, "go_terms": [ { "name": "central nervous system myelin formation", "id": "GO:0032289", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0032289", "evidence": [ { "database": "UniProtKB", "id": "A0AAA9TU91", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TU91" } ], "pmid": "" }, { "name": "cell adhesion", "id": "GO:0007155", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007155", "evidence": [ { "database": "UniProtKB", "id": "A0AAA9TU91", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TU91" } ], "pmid": "" }, { "name": "negative regulation of neuron projection development", "id": "GO:0010977", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0010977", "evidence": [ { "database": "UniProtKB", "id": "A0AAA9TU91", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TU91" } ], "pmid": "" }, { "name": "negative regulation of neuron apoptotic process", "id": "GO:0043524", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0043524", "evidence": [ { "database": "UniProtKB", "id": "A0AAA9TU91", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TU91" } ], "pmid": "" }, { "name": "positive regulation of myelination", "id": "GO:0031643", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0031643", "evidence": [ { "database": "UniProtKB", "id": "A0AAA9TU91", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TU91" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 4, "go_terms": [ { "name": "plasma membrane", "id": "GO:0005886", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005886", "evidence": [ { "database": "UniProtKB", "id": "A0AAA9TU91", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TU91" } ], "pmid": "" }, { "name": "myelin sheath adaxonal region", "id": "GO:0035749", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0035749", "evidence": [ { "database": "UniProtKB", "id": "A0AAA9TU91", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TU91" } ], "pmid": "" }, { "name": "Schmidt-Lanterman incisure", "id": "GO:0043220", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0043220", "evidence": [ { "database": "UniProtKB", "id": "A0AAA9TU91", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TU91" } ], "pmid": "" }, { "name": "paranode region of axon", "id": "GO:0033270", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0033270", "evidence": [ { "database": "UniProtKB", "id": "A0AAA9TU91", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TU91" } ], "pmid": "" } ] }, { "name": "Molecular Function", "total": 4, "go_terms": [ { "name": "protein homodimerization activity", "id": "GO:0042803", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0042803", "evidence": [ { "database": "UniProtKB", "id": "A0AAA9TU91", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TU91" } ], "pmid": "" }, { "name": "carbohydrate binding", "id": "GO:0030246", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030246", "evidence": [ { "database": "UniProtKB", "id": "A0AAA9TU91", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TU91" } ], "pmid": "" }, { "name": "sialic acid binding", "id": "GO:0033691", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0033691", "evidence": [ { 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phosphatase OS=Bos taurus OX=9913 GN=CTDSP1 PE=4 SV=1 CANONICAL=A0AAA9TV14-1" }, "isoforms": [ { "isoform_ac": "A0AAA9RWK4-1", "url": "https://www.uniprot.org/uniprotkb/A0AAA9RWK4/entry", "sequence": { "sequence": "TRRRKEEGAETLSRATVAAAARGARLGGTRSFQLEGKLGDQKSAASQKPRSRGILHSLFCCVCRDDGEALPAHSGAPLLVEENGAVPKTPVQYLLPEAKAQDSDKICVVIDLDETLVHSSFKPVNNADFIIPVEIDGVVHQVYVLKRPHVDEFLQRMGELFECVLFTASLAKYADPVADLLDKWGAFRARLFRESCVFHRGNYVKDLSRLGRDLRRVLILDNSPASYVFHPDNAKSVTKPSPGRRARRTLSSSPSLSRSPRALGRVNTEPSLPPARPSSGSCSISCSPCKHSPLAIFAS", "length": 299, "header": "tr|A0AAA9RWK4-1|A0AAA9TV14_BOVIN Computationally mapped isoform of protein-serine/threonine phosphatase OS=Bos taurus OX=9913 GN=CTDSP1 PE=4 SV=1 CANONICAL=A0AAA9TV14-1" }, "locus": { "chromosome": "2", "start_pos": 106416045, "end_pos": 106408643, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000129453.1", "url": "https://www.ensembl.org/id/ENSBTAT00000129453.1" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000075478.1", "url": "https://www.ensembl.org/id/ENSBTAP00000075478.1" } ] } }, { "isoform_ac": "A0AAA9SLP5-1", "url": "https://www.uniprot.org/uniprotkb/A0AAA9SLP5/entry", "sequence": { "sequence": "FQLEGKLGESLNLQRLGDPGRGLARLGALRSARGDQKSAASQKPRSRGILHSLFCCVCRDDGEALPAHSGAPLLVEENGAVPKTPVQYLLPEAKAQDSDKICVVIDLDETLVHSSFKPVNNADFIIPVEIDGVVHQVYVLKRPHVDEFLQRMGELFECVLFTASLAKYADPVADLLDKWGAFRARLFRESCVFHRGNYVKDLSRLGRDLRRVLILDNSPASYVFHPDNAVPVASWFDNMSDTELHDLLPFFEQLSRVDDVYSVLRQPRPGS", "length": 271, "header": "tr|A0AAA9SLP5-1|A0AAA9TV14_BOVIN Computationally mapped isoform of protein-serine/threonine phosphatase OS=Bos taurus OX=9913 GN=CTDSP1 PE=4 SV=1 CANONICAL=A0AAA9TV14-1" }, "locus": { "chromosome": "2", "start_pos": 106412859, "end_pos": 106408736, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000097175.1", "url": "https://www.ensembl.org/id/ENSBTAT00000097175.1" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000084871.1", "url": "https://www.ensembl.org/id/ENSBTAP00000084871.1" } ] } }, { "isoform_ac": "A0AAA9T0G3-1", "url": "https://www.uniprot.org/uniprotkb/A0AAA9T0G3/entry", "sequence": { "sequence": "NLAPLPSEARGDPSLPPLPSPPRPDSGPSRGGGRAPGPESGRRGARPAPWTARPSLLRSARRKRGARYGAKQTPVQYLLPEAKAQDSDKICVVIDLDETLVHSSFKPVNNADFIIPVEIDGVVHQVYVLKRPHVDEFLQRMGELFECVLFTASLAKYADPVADLLDKWGAFRARLFRESCVFHRGNYVKDLSRLGRDLRRVLILDNSPASYVFHPDNAVPVASWFDNMSDTELHDLLPFFEQLSRVDDVYSVLRQPRPGS", "length": 260, "header": "tr|A0AAA9T0G3-1|A0AAA9TV14_BOVIN Computationally mapped isoform of protein-serine/threonine phosphatase OS=Bos taurus OX=9913 GN=CTDSP1 PE=4 SV=1 CANONICAL=A0AAA9TV14-1" }, "locus": { "chromosome": "2", "start_pos": 106412859, "end_pos": 106408402, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000134549.2", "url": "https://www.ensembl.org/id/ENSBTAT00000134549.2" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000089135.1", "url": "https://www.ensembl.org/id/ENSBTAP00000089135.1" } ] } }, { "isoform_ac": "A0AAA9TV14-1", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TV14/entry", "sequence": { "sequence": "EVLPGDQKSAASQKPRSRGILHSLFCCVCRDDGEALPAHSGAPLLVEENGAVPKTPVQYLLPEAKAQDSDKICVVIDLDETLVHSSFKPVNNADFIIPVEIDGVVHQVYVLKRPHVDEFLQRMGELFECVLFTASLAKYADPVADLLDKWGAFRARLFRESCVFHRGNYVKDLSRLGRDLRRVLILDNSPASYVFHPDNAVPVASWFDNMSDTELHDLLPFFEQLSRVDDVYSVLRQPRPGS", "length": 242, "header": "tr|A0AAA9TV14-1|A0AAA9TV14_BOVIN Isoform 1 of protein-serine/threonine phosphatase OS=Bos taurus OX=9913 GN=CTDSP1 PE=4 SV=1 CANONICAL=A0AAA9TV14-1" }, "locus": { "chromosome": "2", "start_pos": 106412859, "end_pos": 106409359, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000101532.1", "url": "https://www.ensembl.org/id/ENSBTAT00000101532.1" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000102199.1", "url": "https://www.ensembl.org/id/ENSBTAP00000102199.1" } ] } }, { "isoform_ac": "E1BDE3-1", "url": "https://www.uniprot.org/uniprotkb/E1BDE3/entry", "sequence": { "sequence": "MRRPRSCQSPTFGMFREPGSPPLRSSRGSLPPTPPLPPAPRFRPEPGGRPGSRARVRPEGSAPGPMDSSAVITQISKEEARSPLRSKGDQKSAASQKPRSRGILHSLFCCVCRDDGEALPAHSGAPLLVEENGAVPKQTPVQYLLPEAKAQDSDKICVVIDLDETLVHSSFKPVNNADFIIPVEIDGVVHQVYVLKRPHVDEFLQRMGELFECVLFTASLAKYADPVADLLDKWGAFRARLFRESCVFHRGNYVKDLSRLGRDLRRVLILDNSPASYVFHPDNAVPVASWFDNMSDTELHDLLPFFEQLSRVDDVYSVLRQPRPGS", "length": 326, "header": "tr|E1BDE3-1|E1BDE3_BOVIN Computationally mapped isoform of protein-serine/threonine phosphatase OS=Bos taurus OX=9913 GN=CTDSP1 PE=4 SV=3 CANONICAL=A0AAA9TV14-1" }, "locus": { "chromosome": "2", "start_pos": 106412859, "end_pos": 106407951, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000011010.8", "url": "https://www.ensembl.org/id/ENSBTAT00000011010.8" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000011010.6", "url": "https://www.ensembl.org/id/ENSBTAP00000011010.6" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [ "enzyme" ], "publication": [], "pathway": [], "orthologs": [], "go_annotation": { "categories": [ { "name": "Molecular Function", "total": 2, "go_terms": [ { "name": "metal ion binding", "id": "GO:0046872", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0046872", "evidence": [ { "database": "UniProtKB", "id": "A0AAA9TV14", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TV14" } ], "pmid": "" }, { "name": "RNA polymerase II CTD heptapeptide repeat phosphatase activity", "id": "GO:0008420", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008420", "evidence": [ { "database": "UniProtKB", "id": "A0AAA9TV14", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TV14" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 1, "go_terms": [ { "name": "nucleoplasm", "id": "GO:0005654", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005654", "evidence": [ { "database": "UniProtKB", "id": "A0AAA9TV14", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TV14" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 209, "end_pos": 211, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [ { "id": "20629", "name": "", "equation": "O-phospho-L-seryl-[protein] + H2O = L-seryl-[protein] + phosphate", "summary": "", "cellular_location": "", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [ "E1BEW5-1", "A0AAA9TV14-1", "A0AAA9S745-1", "A0A3Q1MV48-1", "F1ME76-1", "E1BAB2-1", "E1BBD9-1", "A0A3Q1N5B2-1", "F1MBQ1-1", "A0AAA9RTM1-1", "A0AAF6YJP2-1", "P48452-1", "F1MI99-1", "G3N3B3-1", "O62830-1", "Q0IIF0-1", "A5PJZ2-1", "Q17QJ3-1", "F6RRD7-1", "Q5BIP9-1", "A0AAA9TT76-1", "A6H772-1", "O62829-1", "P61287-1", "A0AAA9U0H6-1", "Q3ZBF9-1", "Q3SWW9-1", "Q3T0E7-1", "P0C591-1", "P67774-1", "Q0IID7-1", "Q0P594-1", "Q1RMV9-1", "Q2KJ36-1", "Q2PC20-1", "P79126-1", "Q17QI2-1", "Q17QM8-1", "Q2KJD7-1", "E1B9Y5-1", "Q58DC0-1", "A0AAA9SWY4-1", "A0A3Q1LZA9-1", "A0AAA9S454-1", "A0AAA9SCR0-1", "A0AAA9TD32-1", "A0A3Q1N224-1", "E1BMD4-1", "A0AAF6DLF7-1", "F1N580-1", "F1MQM7-1", "F1MW60-1", "F1N719-1", "E1BF95-1", "E1BIE7-1", "F1MEZ2-1", "F1MM08-1", "A0A3Q1MLC5-1", "A0A3Q1MH98-1", "F1MW70-1", "A0A3Q1MZU1-1" ], "evidence": [ { "id": "20629", "database": "Rhea", "url": "https://www.rhea-db.org/rhea/20629" } ] }, { "id": "47004", "name": "", "equation": "O-phospho-L-threonyl-[protein] + H2O = L-threonyl-[protein] + phosphate", "summary": "", "cellular_location": "", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [ "A0AAF6DLF7-1", "F1MI92-1", "A0A3Q1MV48-1", "E1BEW5-1", "F1ME76-1", "E1BAB2-1", "E1BBD9-1", "A0A3Q1N5B2-1", "A0ABI0P1A3-1", "F1MBQ1-1", "A0AAA9RTM1-1", "G3N3B3-1", "A0AAF6YJP2-1", "P48452-1", "O62829-1", "Q0IIF0-1", "A5PJZ2-1", "Q17QJ3-1", "F6RRD7-1", "Q5BIP9-1", "A0AAA9TT76-1", "Q0P594-1", "A6H772-1", "O62830-1", "P61287-1", "A0AAA9U0H6-1", "Q3SWW9-1", "Q3T0E7-1", "P0C591-1", "P67774-1", "Q0IID7-1", "Q1RMV9-1", "Q2KJ36-1", "P79126-1", "Q17QI2-1", "Q17QM8-1", "Q2KJD7-1", "E1B9Y5-1", "E1BIZ2-1", "F1MI99-1", "F1MP34-1", "F1MEZ2-1", "F1MQM7-1", "F1MM08-1", "F1N719-1", "A0AAA9T455-1", "Q58DC0-1", "A0AAA9SWY4-1", "A0A3Q1LZA9-1", "A0AAA9S454-1", "A0AAA9SCR0-1", "A0AAA9TD32-1", "A0AAA9TV14-1", "A0AAA9S745-1", "F1N580-1", "E1BMD4-1", "E1BF95-1", "E1BIE7-1", "A0A3Q1N224-1", "A0A3Q1MLC5-1", "A0A3Q1MH98-1", "F1MW70-1", "A0A3Q1MZU1-1" ], "evidence": [ { "id": "47004", "database": "Rhea", "url": "https://www.rhea-db.org/rhea/47004" } ] } ], "reaction_participants": [], "reaction_enzymes": [ { "uniprot_ac": "A0A3Q1LZA9", "gene_name": "DUSP15", "activity": [ { "ec_number": "3.1.3.16", "activity": "O-phospho-L-threonyl-[protein] + H2O = L-threonyl-[protein] + phosphate.", "evidence": [ { "id": "A0A3Q1LZA9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1LZA9" } ] }, { "ec_number": "3.1.3.48", "activity": "O-phospho-L-tyrosyl-[protein] + H2O = L-tyrosyl-[protein] + phosphate.", "evidence": [ { "id": "A0A3Q1LZA9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1LZA9" } ] }, { "ec_number": "3.1.3.16", "activity": "", "evidence": [ { "id": "A0A3Q1LZA9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1LZA9" } ] }, { "ec_number": "3.1.3.48", "activity": "", "evidence": [ { "id": "A0A3Q1LZA9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1LZA9" } ] } ] }, { "uniprot_ac": "A0A3Q1MH98", "gene_name": "DUSP28", "activity": [ { "ec_number": "3.1.3.16", "activity": "O-phospho-L-threonyl-[protein] + H2O = L-threonyl-[protein] + phosphate.", "evidence": [ { "id": "A0A3Q1MH98", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1MH98" } ] }, { "ec_number": "3.1.3.48", "activity": "O-phospho-L-tyrosyl-[protein] + H2O = L-tyrosyl-[protein] + phosphate.", "evidence": [ { "id": "A0A3Q1MH98", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1MH98" } ] }, { "ec_number": "3.1.3.16", "activity": "", "evidence": [ { "id": "A0A3Q1MH98", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1MH98" } ] }, { "ec_number": "3.1.3.48", "activity": "", "evidence": [ { "id": "A0A3Q1MH98", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1MH98" } ] } ] }, { "uniprot_ac": "A0A3Q1MLC5", "gene_name": "DUSP8", "activity": [ { "ec_number": "3.1.3.16", "activity": "O-phospho-L-threonyl-[protein] + H2O = L-threonyl-[protein] + phosphate.", "evidence": [ { "id": "A0A3Q1MLC5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1MLC5" } ] }, { "ec_number": "3.1.3.48", "activity": "O-phospho-L-tyrosyl-[protein] + H2O = L-tyrosyl-[protein] + phosphate.", "evidence": [ { "id": "A0A3Q1MLC5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1MLC5" } ] }, { "ec_number": "3.1.3.48", "activity": "", "evidence": [ { "id": "A0A3Q1MLC5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1MLC5" } ] }, { "ec_number": "3.1.3.16", "activity": "", "evidence": [ { "id": "A0A3Q1MLC5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1MLC5" } ] } ] }, { "uniprot_ac": "A0A3Q1MV48", "gene_name": "CDC14A", "activity": [ { "ec_number": "3.1.3.16", "activity": "O-phospho-L-threonyl-[protein] + H2O = L-threonyl-[protein] + phosphate.", "evidence": [ { "id": "A0A3Q1MV48", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1MV48" } ] }, { "ec_number": "3.1.3.48", "activity": "O-phospho-L-tyrosyl-[protein] + H2O = L-tyrosyl-[protein] + phosphate.", "evidence": [ { "id": "A0A3Q1MV48", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1MV48" } ] }, { "ec_number": "3.1.3.16", "activity": "", "evidence": [ { "id": "A0A3Q1MV48", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1MV48" } ] }, { "ec_number": "3.1.3.48", "activity": "", "evidence": [ { "id": "A0A3Q1MV48", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1MV48" } ] } ] }, { "uniprot_ac": "A0A3Q1MZU1", "gene_name": "CTDSPL2", "activity": [ { "ec_number": "3.1.3.16", "activity": "O-phospho-L-threonyl-[protein] + H2O = L-threonyl-[protein] + phosphate.", "evidence": [ { "id": "A0A3Q1MZU1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1MZU1" } ] }, { "ec_number": "3.1.3.16", "activity": "", "evidence": [ { "id": "A0A3Q1MZU1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1MZU1" } ] } ] }, { "uniprot_ac": "A0A3Q1N224", "gene_name": "PHLPP1", "activity": [ { "ec_number": "3.1.3.16", "activity": "O-phospho-L-threonyl-[protein] + H2O = L-threonyl-[protein] + phosphate.", "evidence": [ { "id": "A0A3Q1N224", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1N224" } ] }, { "ec_number": "3.1.3.16", "activity": "", "evidence": [ { "id": "A0A3Q1N224", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1N224" } ] } ] }, { "uniprot_ac": "A0A3Q1N5B2", "gene_name": "CDC14B", "activity": [ { "ec_number": "3.1.3.48", "activity": "O-phospho-L-tyrosyl-[protein] + H2O = L-tyrosyl-[protein] + phosphate.", "evidence": [ { "id": "A0A3Q1N5B2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1N5B2" } ] }, { "ec_number": "3.1.3.48", "activity": "", "evidence": [ { "id": "A0A3Q1N5B2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1N5B2" } ] } ] }, { "uniprot_ac": "A0AAA9RTM1", "gene_name": "DUSP22", "activity": [ { "ec_number": "3.1.3.16", "activity": "O-phospho-L-threonyl-[protein] + H2O = L-threonyl-[protein] + phosphate.", "evidence": [ { "id": "A0AAA9RTM1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9RTM1" } ] }, { "ec_number": "3.1.3.48", "activity": "O-phospho-L-tyrosyl-[protein] + H2O = L-tyrosyl-[protein] + phosphate.", "evidence": [ { "id": "A0AAA9RTM1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9RTM1" } ] }, { "ec_number": "3.1.3.16", "activity": "", "evidence": [ { "id": "A0AAA9RTM1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9RTM1" } ] }, { "ec_number": "3.1.3.48", "activity": "", "evidence": [ { "id": "A0AAA9RTM1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9RTM1" } ] } ] }, { "uniprot_ac": "A0AAA9S454", "gene_name": "LOC112441581", "activity": [ { "ec_number": "3.1.3.16", "activity": "O-phospho-L-threonyl-[protein] + H2O = L-threonyl-[protein] + phosphate.", "evidence": [ { "id": "A0AAA9S454", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9S454" } ] }, { "ec_number": "3.1.3.16", "activity": "", "evidence": [ { "id": "A0AAA9S454", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9S454" } ] } ] }, { "uniprot_ac": "A0AAA9S745", "gene_name": "CTDSPL", "activity": [ { "ec_number": "3.1.3.16", "activity": "O-phospho-L-threonyl-[protein] + H2O = L-threonyl-[protein] + phosphate.", "evidence": [ { "id": "A0AAA9S745", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9S745" } ] }, { "ec_number": "3.1.3.16", "activity": "", "evidence": [ { "id": "A0AAA9S745", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9S745" } ] } ] }, { "uniprot_ac": "A0AAA9SCR0", "gene_name": "LOC112441582", "activity": [ { "ec_number": "3.1.3.16", "activity": "O-phospho-L-threonyl-[protein] + H2O = L-threonyl-[protein] + phosphate.", "evidence": [ { "id": "A0AAA9SCR0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9SCR0" } ] }, { "ec_number": "3.1.3.16", "activity": "", "evidence": [ { "id": "A0AAA9SCR0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9SCR0" } ] } ] }, { "uniprot_ac": "A0AAA9SWY4", "gene_name": "CPPED1", "activity": [ { "ec_number": "3.1.3.16", "activity": "O-phospho-L-threonyl-[protein] + H2O = L-threonyl-[protein] + phosphate.", "evidence": [ { "id": "A0AAA9SWY4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9SWY4" } ] }, { "ec_number": "3.1.3.16", "activity": "", "evidence": [ { "id": "A0AAA9SWY4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9SWY4" } ] } ] }, { "uniprot_ac": "A0AAA9T455", "gene_name": "CDKN3", "activity": [ { "ec_number": "3.1.3.16", "activity": "O-phospho-L-threonyl-[protein] + H2O = L-threonyl-[protein] + phosphate.", "evidence": [ { "id": "A0AAA9T455", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9T455" } ] }, { "ec_number": "3.1.3.48", "activity": "O-phospho-L-tyrosyl-[protein] + H2O = L-tyrosyl-[protein] + phosphate.", "evidence": [ { "id": "A0AAA9T455", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9T455" } ] }, { "ec_number": "3.1.3.16", "activity": "", "evidence": [ { "id": "A0AAA9T455", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9T455" } ] }, { "ec_number": "3.1.3.48", "activity": "", "evidence": [ { "id": "A0AAA9T455", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9T455" } ] } ] }, { "uniprot_ac": "A0AAA9TD32", "gene_name": "CTDP1", "activity": [ { "ec_number": "3.1.3.16", "activity": "O-phospho-L-threonyl-[protein] + H2O = L-threonyl-[protein] + phosphate.", "evidence": [ { "id": "A0AAA9TD32", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TD32" } ] }, { "ec_number": "3.1.3.16", "activity": "", "evidence": [ { "id": "A0AAA9TD32", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TD32" } ] } ] }, { "uniprot_ac": "A0AAA9TT76", "gene_name": "PPP3CC", "activity": [ { "ec_number": "3.1.3.16", "activity": "O-phospho-L-threonyl-[protein] + H2O = L-threonyl-[protein] + phosphate.", "evidence": [ { "id": "A0AAA9TT76", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TT76" } ] }, { "ec_number": "3.1.3.16", "activity": "", "evidence": [ { "id": "A0AAA9TT76", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TT76" } ] } ] }, { "uniprot_ac": "A0AAA9TV14", "gene_name": "CTDSP1", "activity": [ { "ec_number": "3.1.3.16", "activity": "O-phospho-L-threonyl-[protein] + H2O = L-threonyl-[protein] + phosphate.", "evidence": [ { "id": "A0AAA9TV14", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TV14" } ] }, { "ec_number": "3.1.3.16", "activity": "", "evidence": [ { "id": "A0AAA9TV14", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TV14" } ] } ] }, { "uniprot_ac": "A0AAA9U0H6", "gene_name": "PTEN", "activity": [ { "ec_number": "3.1.3.67", "activity": "a 1,2-diacyl-sn-glycero-3-phospho-(1D-myo-inositol-3,4,5-trisphosphate) + H2O = a 1,2-diacyl-sn-glycero-3-phospho-(1D-myo-inositol-4,5-bisphosphate) + phosphate.", "evidence": [ { "id": "A0AAA9U0H6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9U0H6" } ] }, { "ec_number": "3.1.3.16", "activity": "O-phospho-L-threonyl-[protein] + H2O = L-threonyl-[protein] + phosphate.", "evidence": [ { "id": "A0AAA9U0H6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9U0H6" } ] }, { "ec_number": "3.1.3.48", "activity": "O-phospho-L-tyrosyl-[protein] + H2O = L-tyrosyl-[protein] + phosphate.", "evidence": [ { "id": "A0AAA9U0H6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9U0H6" } ] }, { "ec_number": "3.1.3.48", "activity": "", "evidence": [ { "id": "A0AAA9U0H6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9U0H6" } ] }, { "ec_number": "3.1.3.67", "activity": "", "evidence": [ { "id": "A0AAA9U0H6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9U0H6" } ] }, { "ec_number": "3.1.3.16", "activity": "", "evidence": [ { "id": "A0AAA9U0H6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9U0H6" } ] } ] }, { "uniprot_ac": "A0AAF6DLF7", "gene_name": "DUSP7", "activity": [ { "ec_number": "3.1.3.16", "activity": "O-phospho-L-threonyl-[protein] + H2O = L-threonyl-[protein] + phosphate.", "evidence": [ { "id": "A0AAF6DLF7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAF6DLF7" } ] }, { "ec_number": "3.1.3.48", "activity": "O-phospho-L-tyrosyl-[protein] + H2O = L-tyrosyl-[protein] + phosphate.", "evidence": [ { "id": "A0AAF6DLF7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAF6DLF7" } ] }, { "ec_number": "3.1.3.48", "activity": "", "evidence": [ { "id": "A0AAF6DLF7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAF6DLF7" } ] }, { "ec_number": "3.1.3.16", "activity": "", "evidence": [ { "id": "A0AAF6DLF7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAF6DLF7" } ] } ] }, { "uniprot_ac": "A0AAF6YJP2", "gene_name": "SSU72", "activity": [ { "ec_number": "3.1.3.16", "activity": "O-phospho-L-threonyl-[protein] + H2O = L-threonyl-[protein] + phosphate.", "evidence": [ { "id": "A0AAF6YJP2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAF6YJP2" } ] }, { "ec_number": "3.1.3.16", "activity": "", "evidence": [ { "id": "A0AAF6YJP2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAF6YJP2" } ] } ] }, { "uniprot_ac": "A0ABI0P1A3", "gene_name": "SSH2", "activity": [ { "ec_number": "3.1.3.16", "activity": "O-phospho-L-threonyl-[protein] + H2O = L-threonyl-[protein] + phosphate.", "evidence": [ { "id": "A0ABI0P1A3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0ABI0P1A3" } ] }, { "ec_number": "3.1.3.16", "activity": "", "evidence": [ { "id": "A0ABI0P1A3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0ABI0P1A3" } ] } ] }, { "uniprot_ac": "A5PJZ2", "gene_name": "PPM1L", "activity": [ { "ec_number": "3.1.3.16", "activity": "O-phospho-L-threonyl-[protein] + H2O = L-threonyl-[protein] + phosphate.", "evidence": [ { "id": "A5PJZ2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A5PJZ2" } ] }, { "ec_number": "3.1.3.16", "activity": "", "evidence": [ { "id": "A5PJZ2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A5PJZ2" } ] } ] }, { "uniprot_ac": "A6H772", "gene_name": "PPP4C", "activity": [ { "ec_number": "3.1.3.16", "activity": "O-phospho-L-threonyl-[protein] + H2O = L-threonyl-[protein] + phosphate.", "evidence": [ { "id": "A6H772", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A6H772" } ] }, { "ec_number": "3.1.3.16", "activity": "", "evidence": [ { "id": "A6H772", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A6H772" } ] } ] }, { "uniprot_ac": "E1B9Y5", "gene_name": "PPEF2", "activity": [ { "ec_number": "3.1.3.16", "activity": "O-phospho-L-threonyl-[protein] + H2O = L-threonyl-[protein] + phosphate.", "evidence": [ { "id": "E1B9Y5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1B9Y5" } ] }, { "ec_number": "3.1.3.16", "activity": "", "evidence": [ { "id": "E1B9Y5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1B9Y5" } ] } ] }, { "uniprot_ac": "E1BAB2", "gene_name": "", "activity": [ { "ec_number": "3.1.3.16", "activity": "O-phospho-L-threonyl-[protein] + H2O = L-threonyl-[protein] + phosphate.", "evidence": [ { "id": "E1BAB2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BAB2" } ] }, { "ec_number": "3.1.3.16", "activity": "", "evidence": [ { "id": "E1BAB2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BAB2" } ] } ] }, { "uniprot_ac": "E1BBD9", "gene_name": "LOC112445820", "activity": [ { "ec_number": "3.1.3.16", "activity": "O-phospho-L-threonyl-[protein] + H2O = L-threonyl-[protein] + phosphate.", "evidence": [ { "id": "E1BBD9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BBD9" } ] }, { "ec_number": "3.1.3.16", "activity": "", "evidence": [ { "id": "E1BBD9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BBD9" } ] } ] }, { "uniprot_ac": "E1BEW5", "gene_name": "PPTC7", "activity": [ { "ec_number": "3.1.3.16", "activity": "O-phospho-L-threonyl-[protein] + H2O = L-threonyl-[protein] + phosphate.", "evidence": [ { "id": "E1BEW5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BEW5" } ] }, { "ec_number": "3.1.3.16", "activity": "", "evidence": [ { "id": "E1BEW5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BEW5" } ] } ] }, { "uniprot_ac": "E1BF95", "gene_name": "PPM1F", "activity": [ { "ec_number": "3.1.3.16", "activity": "O-phospho-L-threonyl-[protein] + H2O = L-threonyl-[protein] + phosphate.", "evidence": [ { "id": "E1BF95", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BF95" } ] }, { "ec_number": "3.1.3.16", "activity": "", "evidence": [ { "id": "E1BF95", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BF95" } ] } ] }, { "uniprot_ac": "E1BIE7", "gene_name": "PGAM5", "activity": [ { "ec_number": "3.1.3.16", "activity": "O-phospho-L-threonyl-[protein] + H2O = L-threonyl-[protein] + phosphate.", "evidence": [ { "id": "E1BIE7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BIE7" } ] }, { "ec_number": "3.1.3.16", "activity": "", "evidence": [ { "id": "E1BIE7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BIE7" } ] } ] }, { "uniprot_ac": "E1BIZ2", "gene_name": "SSH1", "activity": [ { "ec_number": "3.1.3.16", "activity": "O-phospho-L-threonyl-[protein] + H2O = L-threonyl-[protein] + phosphate.", "evidence": [ { "id": "E1BIZ2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BIZ2" } ] }, { "ec_number": "3.1.3.16", "activity": "", "evidence": [ { "id": "E1BIZ2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BIZ2" } ] } ] }, { "uniprot_ac": "E1BMD4", "gene_name": "PHLPP2", "activity": [ { "ec_number": "3.1.3.16", "activity": "O-phospho-L-threonyl-[protein] + H2O = L-threonyl-[protein] + phosphate.", "evidence": [ { "id": "E1BMD4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BMD4" } ] }, { "ec_number": "3.1.3.16", "activity": "", "evidence": [ { "id": "E1BMD4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BMD4" } ] } ] }, { "uniprot_ac": "F1MBQ1", "gene_name": "PPEF1", "activity": [ { "ec_number": "3.1.3.16", "activity": "O-phospho-L-threonyl-[protein] + H2O = L-threonyl-[protein] + phosphate.", "evidence": [ { "id": "F1MBQ1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MBQ1" } ] }, { "ec_number": "3.1.3.16", "activity": "", "evidence": [ { "id": "F1MBQ1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MBQ1" } ] } ] }, { "uniprot_ac": "F1ME76", "gene_name": "DUSP13B", "activity": [ { "ec_number": "3.1.3.16", "activity": "O-phospho-L-threonyl-[protein] + H2O = L-threonyl-[protein] + phosphate.", "evidence": [ { "id": "F1ME76", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1ME76" } ] }, { "ec_number": "3.1.3.48", "activity": "O-phospho-L-tyrosyl-[protein] + H2O = L-tyrosyl-[protein] + phosphate.", "evidence": [ { "id": "F1ME76", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1ME76" } ] }, { "ec_number": "3.1.3.16", "activity": "", "evidence": [ { "id": "F1ME76", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1ME76" } ] }, { "ec_number": "3.1.3.48", "activity": "", "evidence": [ { "id": "F1ME76", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1ME76" } ] } ] }, { "uniprot_ac": "F1MEZ2", "gene_name": "DUSP9", "activity": [ { "ec_number": "3.1.3.16", "activity": "O-phospho-L-threonyl-[protein] + H2O = L-threonyl-[protein] + phosphate.", "evidence": [ { "id": "F1MEZ2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MEZ2" } ] }, { "ec_number": "3.1.3.48", "activity": "O-phospho-L-tyrosyl-[protein] + H2O = L-tyrosyl-[protein] + phosphate.", "evidence": [ { "id": "F1MEZ2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MEZ2" } ] }, { "ec_number": "3.1.3.48", "activity": "", "evidence": [ { "id": "F1MEZ2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MEZ2" } ] }, { "ec_number": "3.1.3.16", "activity": "", "evidence": [ { "id": "F1MEZ2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MEZ2" } ] } ] }, { "uniprot_ac": "F1MI92", "gene_name": "SSH3", "activity": [ { "ec_number": "3.1.3.16", "activity": "O-phospho-L-threonyl-[protein] + H2O = L-threonyl-[protein] + phosphate.", "evidence": [ { "id": "F1MI92", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MI92" } ] }, { "ec_number": "3.1.3.16", "activity": "", "evidence": [ { "id": "F1MI92", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MI92" } ] } ] }, { "uniprot_ac": "F1MI99", "gene_name": "DUSP1", "activity": [ { "ec_number": "3.1.3.16", "activity": "O-phospho-L-threonyl-[protein] + H2O = L-threonyl-[protein] + phosphate.", "evidence": [ { "id": "F1MI99", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MI99" } ] }, { "ec_number": "3.1.3.48", "activity": "O-phospho-L-tyrosyl-[protein] + H2O = L-tyrosyl-[protein] + phosphate.", "evidence": [ { "id": "F1MI99", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MI99" } ] }, { "ec_number": "3.1.3.48", "activity": "", "evidence": [ { "id": "F1MI99", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MI99" } ] }, { "ec_number": "3.1.3.16", "activity": "", "evidence": [ { "id": "F1MI99", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MI99" } ] } ] }, { "uniprot_ac": "F1MM08", "gene_name": "DUSP4", "activity": [ { "ec_number": "3.1.3.16", "activity": "O-phospho-L-threonyl-[protein] + H2O = L-threonyl-[protein] + phosphate.", "evidence": [ { "id": "F1MM08", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MM08" } ] }, { "ec_number": "3.1.3.48", "activity": "O-phospho-L-tyrosyl-[protein] + H2O = L-tyrosyl-[protein] + phosphate.", "evidence": [ { "id": "F1MM08", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MM08" } ] }, { "ec_number": "3.1.3.48", "activity": "", "evidence": [ { "id": "F1MM08", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MM08" } ] }, { "ec_number": "3.1.3.16", "activity": "", "evidence": [ { "id": "F1MM08", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MM08" } ] } ] }, { "uniprot_ac": "F1MP34", "gene_name": "DUSP2", "activity": [ { "ec_number": "3.1.3.16", "activity": "O-phospho-L-threonyl-[protein] + H2O = L-threonyl-[protein] + phosphate.", "evidence": [ { "id": "F1MP34", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MP34" } ] }, { "ec_number": "3.1.3.48", "activity": "O-phospho-L-tyrosyl-[protein] + H2O = L-tyrosyl-[protein] + phosphate.", "evidence": [ { "id": "F1MP34", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MP34" } ] }, { "ec_number": "3.1.3.48", "activity": "", "evidence": [ { "id": "F1MP34", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MP34" } ] }, { "ec_number": "3.1.3.16", "activity": "", "evidence": [ { "id": "F1MP34", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MP34" } ] } ] }, { "uniprot_ac": "F1MQM7", "gene_name": "DUSP5", "activity": [ { "ec_number": "3.1.3.16", "activity": "O-phospho-L-threonyl-[protein] + H2O = L-threonyl-[protein] + phosphate.", "evidence": [ { "id": "F1MQM7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MQM7" } ] }, { "ec_number": "3.1.3.48", "activity": "O-phospho-L-tyrosyl-[protein] + H2O = L-tyrosyl-[protein] + phosphate.", "evidence": [ { "id": "F1MQM7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MQM7" } ] }, { "ec_number": "3.1.3.16", "activity": "", "evidence": [ { "id": "F1MQM7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MQM7" } ] }, { "ec_number": "3.1.3.48", "activity": "", "evidence": [ { "id": "F1MQM7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MQM7" } ] } ] }, { "uniprot_ac": "F1MW60", "gene_name": "PDXP", "activity": [ { "ec_number": "3.1.3.74", "activity": "pyridoxal 5'-phosphate + H2O = pyridoxal + phosphate.", "evidence": [ { "id": "F1MW60", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MW60" } ] }, { "ec_number": "3.1.3.16", "activity": "O-phospho-L-threonyl-[protein] + H2O = L-threonyl-[protein] + phosphate.", "evidence": [ { "id": "F1MW60", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MW60" } ] }, { "ec_number": "3.1.3.16", "activity": "", "evidence": [ { "id": "F1MW60", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MW60" } ] }, { "ec_number": "3.1.3.74", "activity": "", "evidence": [ { "id": "F1MW60", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MW60" } ] } ] }, { "uniprot_ac": "F1MW70", "gene_name": "DUSP12", "activity": [ { "ec_number": "3.1.3.16", "activity": "O-phospho-L-threonyl-[protein] + H2O = L-threonyl-[protein] + phosphate.", "evidence": [ { "id": "F1MW70", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MW70" } ] }, { "ec_number": "3.1.3.48", "activity": "O-phospho-L-tyrosyl-[protein] + H2O = L-tyrosyl-[protein] + phosphate.", "evidence": [ { "id": "F1MW70", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MW70" } ] }, { "ec_number": "3.1.3.48", "activity": "", "evidence": [ { "id": "F1MW70", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MW70" } ] }, { "ec_number": "3.1.3.16", "activity": "", "evidence": [ { "id": "F1MW70", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MW70" } ] } ] }, { "uniprot_ac": "F1N580", "gene_name": "PPM1E", "activity": [ { "ec_number": "3.1.3.16", "activity": "O-phospho-L-threonyl-[protein] + H2O = L-threonyl-[protein] + phosphate.", "evidence": [ { "id": "F1N580", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1N580" } ] }, { "ec_number": "3.1.3.16", "activity": "", "evidence": [ { "id": "F1N580", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1N580" } ] } ] }, { "uniprot_ac": "F1N719", "gene_name": "PPP5C", "activity": [ { "ec_number": "3.1.3.16", "activity": "O-phospho-L-threonyl-[protein] + H2O = L-threonyl-[protein] + phosphate.", "evidence": [ { "id": "F1N719", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1N719" } ] }, { "ec_number": "3.1.3.16", "activity": "", "evidence": [ { "id": "F1N719", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1N719" } ] } ] }, { "uniprot_ac": "F6RRD7", "gene_name": "RPAP2", "activity": [ { "ec_number": "3.1.3.16", "activity": "O-phospho-L-threonyl-[protein] + H2O = L-threonyl-[protein] + phosphate.", "evidence": [ { "id": "F6RRD7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F6RRD7" } ] }, { "ec_number": "3.1.3.16", "activity": "", "evidence": [ { "id": "F6RRD7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F6RRD7" } ] } ] }, { "uniprot_ac": "G3N3B3", "gene_name": "PPM1N", "activity": [ { "ec_number": "3.1.3.16", "activity": "O-phospho-L-threonyl-[protein] + H2O = L-threonyl-[protein] + phosphate.", "evidence": [ { "id": "G3N3B3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3N3B3" } ] }, { "ec_number": "3.1.3.16", "activity": "", "evidence": [ { "id": "G3N3B3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3N3B3" } ] } ] }, { "uniprot_ac": "O62829", "gene_name": "PPM1A", "activity": [ { "ec_number": "3.1.3.16", "activity": "O-phospho-L-threonyl-[protein] + H2O = L-threonyl-[protein] + phosphate.", "evidence": [ { "id": "O62829", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/O62829" } ] }, { "ec_number": "3.1.3.16", "activity": "", "evidence": [ { "id": "O62829", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/O62829" } ] } ] }, { "uniprot_ac": "O62830", "gene_name": "PPM1B", "activity": [ { "ec_number": "3.1.3.16", "activity": "O-phospho-L-threonyl-[protein] + H2O = L-threonyl-[protein] + phosphate.", "evidence": [ { "id": "O62830", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/O62830" } ] }, { "ec_number": "3.1.3.16", "activity": "", "evidence": [ { "id": "O62830", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/O62830" } ] } ] }, { "uniprot_ac": "P0C591", "gene_name": "DUSP29", "activity": [ { "ec_number": "3.1.3.16", "activity": "O-phospho-L-threonyl-[protein] + H2O = L-threonyl-[protein] + phosphate.", "evidence": [ { "id": "P0C591", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P0C591" } ] }, { "ec_number": "3.1.3.48", "activity": "O-phospho-L-tyrosyl-[protein] + H2O = L-tyrosyl-[protein] + phosphate.", "evidence": [ { "id": "P0C591", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P0C591" } ] } ] }, { "uniprot_ac": "P48452", "gene_name": "PPP3CA", "activity": [ { "ec_number": "3.1.3.16", "activity": "O-phospho-L-threonyl-[protein] + H2O = L-threonyl-[protein] + phosphate.", "evidence": [ { "id": "P48452", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P48452" } ] }, { "ec_number": "3.1.3.16", "activity": "", "evidence": [ { "id": "P48452", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P48452" } ] } ] }, { "uniprot_ac": "P61287", "gene_name": "PPP1CC", "activity": [ { "ec_number": "3.1.3.16", "activity": "O-phospho-L-threonyl-[protein] + H2O = L-threonyl-[protein] + phosphate.", "evidence": [ { "id": "P61287", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P61287" } ] }, { "ec_number": "3.1.3.16", "activity": "", "evidence": [ { "id": "P61287", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P61287" } ] } ] }, { "uniprot_ac": "P67774", "gene_name": "PPP2CA", "activity": [ { "ec_number": "3.1.3.16", "activity": "O-phospho-L-threonyl-[protein] + H2O = L-threonyl-[protein] + phosphate.", "evidence": [ { "id": "P67774", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P67774" } ] }, { "ec_number": "3.1.3.16", "activity": "", "evidence": [ { "id": "P67774", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P67774" } ] } ] }, { "uniprot_ac": "P79126", "gene_name": "PPM1G", "activity": [ { "ec_number": "3.1.3.16", "activity": "O-phospho-L-threonyl-[protein] + H2O = L-threonyl-[protein] + phosphate.", "evidence": [ { "id": "P79126", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P79126" } ] }, { "ec_number": "3.1.3.16", "activity": "", "evidence": [ { "id": "P79126", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P79126" } ] } ] }, { "uniprot_ac": "Q0IID7", "gene_name": "DUSP10", "activity": [ { "ec_number": "3.1.3.16", "activity": "O-phospho-L-threonyl-[protein] + H2O = L-threonyl-[protein] + phosphate.", "evidence": [ { "id": "Q0IID7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q0IID7" } ] }, { "ec_number": "3.1.3.48", "activity": "O-phospho-L-tyrosyl-[protein] + H2O = L-tyrosyl-[protein] + phosphate.", "evidence": [ { "id": "Q0IID7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q0IID7" } ] }, { "ec_number": "3.1.3.16", "activity": "", "evidence": [ { "id": "Q0IID7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q0IID7" } ] }, { "ec_number": "3.1.3.48", "activity": "", "evidence": [ { "id": "Q0IID7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q0IID7" } ] } ] }, { "uniprot_ac": "Q0IIF0", "gene_name": "ILKAP", "activity": [ { "ec_number": "3.1.3.16", "activity": "O-phospho-L-threonyl-[protein] + H2O = L-threonyl-[protein] + phosphate.", "evidence": [ { "id": "Q0IIF0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q0IIF0" } ] }, { "ec_number": "3.1.3.16", "activity": "", "evidence": [ { "id": "Q0IIF0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q0IIF0" } ] } ] }, { "uniprot_ac": "Q0P594", "gene_name": "PPP2CB", "activity": [ { "ec_number": "3.1.3.16", "activity": "O-phospho-L-threonyl-[protein] + H2O = L-threonyl-[protein] + phosphate.", "evidence": [ { "id": "Q0P594", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q0P594" } ] }, { "ec_number": "3.1.3.16", "activity": "", "evidence": [ { "id": "Q0P594", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q0P594" } ] } ] }, { "uniprot_ac": "Q17QI2", "gene_name": "SSU72", "activity": [ { "ec_number": "3.1.3.16", "activity": "O-phospho-L-threonyl-[protein] + H2O = L-threonyl-[protein] + phosphate.", "evidence": [ { "id": "Q17QI2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q17QI2" } ] }, { "ec_number": "3.1.3.16", "activity": "", "evidence": [ { "id": "Q17QI2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q17QI2" } ] } ] }, { "uniprot_ac": "Q17QJ3", "gene_name": "DUSP26", "activity": [ { "ec_number": "3.1.3.16", "activity": "O-phospho-L-threonyl-[protein] + H2O = L-threonyl-[protein] + phosphate.", "evidence": [ { "id": "Q17QJ3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q17QJ3" } ] }, { "ec_number": "3.1.3.48", "activity": "O-phospho-L-tyrosyl-[protein] + H2O = L-tyrosyl-[protein] + phosphate.", "evidence": [ { "id": "Q17QJ3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q17QJ3" } ] }, { "ec_number": "3.1.3.48", "activity": "", "evidence": [ { "id": "Q17QJ3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q17QJ3" } ] }, { "ec_number": "3.1.3.16", "activity": "", "evidence": [ { "id": "Q17QJ3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q17QJ3" } ] } ] }, { "uniprot_ac": "Q17QM8", "gene_name": "DUSP14", "activity": [ { "ec_number": "3.1.3.16", "activity": "O-phospho-L-threonyl-[protein] + H2O = L-threonyl-[protein] + phosphate.", "evidence": [ { "id": "Q17QM8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q17QM8" } ] }, { "ec_number": "3.1.3.48", "activity": "O-phospho-L-tyrosyl-[protein] + H2O = L-tyrosyl-[protein] + phosphate.", "evidence": [ { "id": "Q17QM8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q17QM8" } ] }, { "ec_number": "3.1.3.16", "activity": "", "evidence": [ { "id": "Q17QM8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q17QM8" } ] }, { "ec_number": "3.1.3.48", "activity": "", "evidence": [ { "id": "Q17QM8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q17QM8" } ] } ] }, { "uniprot_ac": "Q1RMV9", "gene_name": "CTDNEP1", "activity": [ { "ec_number": "3.1.3.16", "activity": "O-phospho-L-threonyl-[protein] + H2O = L-threonyl-[protein] + phosphate.", "evidence": [ { "id": "Q1RMV9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q1RMV9" } ] }, { "ec_number": "3.1.3.16", "activity": "", "evidence": [ { "id": "Q1RMV9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q1RMV9" } ] } ] }, { "uniprot_ac": "Q2KJ36", "gene_name": "DUSP6", "activity": [ { "ec_number": "3.1.3.16", "activity": "O-phospho-L-threonyl-[protein] + H2O = L-threonyl-[protein] + phosphate.", "evidence": [ { "id": "Q2KJ36", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q2KJ36" } ] }, { "ec_number": "3.1.3.48", "activity": "O-phospho-L-tyrosyl-[protein] + H2O = L-tyrosyl-[protein] + phosphate.", "evidence": [ { "id": "Q2KJ36", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q2KJ36" } ] }, { "ec_number": "3.1.3.48", "activity": "", "evidence": [ { "id": "Q2KJ36", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q2KJ36" } ] }, { "ec_number": "3.1.3.16", "activity": "", "evidence": [ { "id": "Q2KJ36", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q2KJ36" } ] } ] }, { "uniprot_ac": "Q2KJD7", "gene_name": "UBLCP1", "activity": [ { "ec_number": "3.1.3.16", "activity": "O-phospho-L-threonyl-[protein] + H2O = L-threonyl-[protein] + phosphate.", "evidence": [ { "id": "Q2KJD7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q2KJD7" } ] }, { "ec_number": "3.1.3.16", "activity": "", "evidence": [ { "id": "Q2KJD7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q2KJD7" } ] } ] }, { "uniprot_ac": "Q2PC20", "gene_name": "PPM1K", "activity": [ { "ec_number": "3.1.3.16", "activity": "O-phospho-L-threonyl-[protein] + H2O = L-threonyl-[protein] + phosphate.", "evidence": [ { "id": "Q2PC20", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q2PC20" } ] }, { "ec_number": "3.1.3.52", "activity": "O-phospho-L-seryl-[3-methyl-2-oxobutanoate dehydrogenase] + H2O = L-seryl-[3-methyl-2-oxobutanoate dehydrogenase] + phosphate.", "evidence": [ { "id": "Q2PC20", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q2PC20" } ] }, { "ec_number": "3.1.3.52", "activity": "", "evidence": [ { "id": "Q2PC20", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q2PC20" } ] }, { "ec_number": "3.1.3.16", "activity": "", "evidence": [ { "id": "Q2PC20", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q2PC20" } ] } ] }, { "uniprot_ac": "Q3SWW9", "gene_name": "PPP1CB", "activity": [ { "ec_number": "3.1.3.53", "activity": "O-phospho-L-threonyl-[myosin light chain] + H2O = L-threonyl-[myosin light chain] + phosphate.", "evidence": [ { "id": "Q3SWW9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q3SWW9" } ] }, { "ec_number": "3.1.3.16", "activity": "O-phospho-L-threonyl-[protein] + H2O = L-threonyl-[protein] + phosphate.", "evidence": [ { "id": "Q3SWW9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q3SWW9" } ] }, { "ec_number": "3.1.3.16", "activity": "", "evidence": [ { "id": "Q3SWW9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q3SWW9" } ] }, { "ec_number": "3.1.3.53", "activity": "", "evidence": [ { "id": "Q3SWW9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q3SWW9" } ] } ] }, { "uniprot_ac": "Q3T0E7", "gene_name": "PPP1CA", "activity": [ { "ec_number": "3.1.3.16", "activity": "O-phospho-L-threonyl-[protein] + H2O = L-threonyl-[protein] + phosphate.", "evidence": [ { "id": "Q3T0E7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q3T0E7" } ] }, { "ec_number": "3.1.3.16", "activity": "", "evidence": [ { "id": "Q3T0E7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q3T0E7" } ] } ] }, { "uniprot_ac": "Q3ZBF9", "gene_name": "PDXP", "activity": [ { "ec_number": "3.1.3.74", "activity": "pyridoxal 5'-phosphate + H2O = pyridoxal + phosphate.", "evidence": [ { "id": "Q3ZBF9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q3ZBF9" } ] }, { "ec_number": "3.1.3.16", "activity": "O-phospho-L-threonyl-[protein] + H2O = L-threonyl-[protein] + phosphate.", "evidence": [ { "id": "Q3ZBF9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q3ZBF9" } ] }, { "ec_number": "3.1.3.74", "activity": "", "evidence": [ { "id": "Q3ZBF9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q3ZBF9" } ] }, { "ec_number": "3.1.3.16", "activity": "", "evidence": [ { "id": "Q3ZBF9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q3ZBF9" } ] } ] }, { "uniprot_ac": "Q58DC0", "gene_name": "CPPED1", "activity": [ { "ec_number": "3.1.3.16", "activity": "O-phospho-L-threonyl-[protein] + H2O = L-threonyl-[protein] + phosphate.", "evidence": [ { "id": "Q58DC0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q58DC0" } ] }, { "ec_number": "3.1.3.16", "activity": "", "evidence": [ { "id": "Q58DC0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q58DC0" } ] } ] }, { "uniprot_ac": "Q5BIP9", "gene_name": "DUSP18", "activity": [ { "ec_number": "3.1.3.16", "activity": "O-phospho-L-threonyl-[protein] + H2O = L-threonyl-[protein] + phosphate.", "evidence": [ { "id": "Q5BIP9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q5BIP9" } ] }, { "ec_number": "3.1.3.48", "activity": "O-phospho-L-tyrosyl-[protein] + H2O = L-tyrosyl-[protein] + phosphate.", "evidence": [ { "id": "Q5BIP9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q5BIP9" } ] }, { "ec_number": "3.1.3.16", "activity": "", "evidence": [ { "id": "Q5BIP9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q5BIP9" } ] }, { "ec_number": "3.1.3.48", "activity": "", "evidence": [ { "id": "Q5BIP9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q5BIP9" } ] } ] } ], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A0AAA9TV14", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TV14" }, { "id": "PS50969", "database": "PROSITE", "url": "https://prosite.expasy.org/PS50969" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "FCP1 homology", "eco_id": "ECO_0000259", "start_pos": 67, "end_pos": 225, "start_aa": "Gln", "end_aa": "Leu", "glycosite_overlap": [] } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [ { "ec_number": "3.1.3.16", "ec_name": "O-phospho-L-threonyl-[protein] + H2O = L-threonyl-[protein] + phosphate.", "evidence": [ { "id": "3.1.3.16", "database": "Rhea", "url": "https://www.rhea-db.org/rhea/?query=ec:3.1.3.16" }, { "id": "3.1.3.16", "database": "BRENDA Enzymes", "url": "https://www.brenda-enzymes.org/enzyme.php?ecno=3.1.3.16" } ] } ], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 209, "end_pos": 211 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ], "tool_support": { "graph_view": "yes" } }, { "uniprot_canonical_ac": "A0AAA9TSD9-1", "uniprot_ac": "A0AAA9TSD9", "uniprot_id": "A0AAA9TSD9_BOVIN", "mass": { "chemical_mass": 94879.0, "monoisotopic_mass": 94879.0 }, "refseq": {}, "gene_names": [ { "name": "AP1G1", "type": "recommended", "evidence": [ { "id": "A0AAA9TSD9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TSD9" } ] } ], "protein_names": [ { "name": "AP-1 complex subunit gamma", "type": "recommended", "evidence": [ { "id": "A0AAA9TSD9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TSD9/entry#names_and_taxonomy" } ] } ], "function": [ { "annotation": "Subunit of clathrin-associated adaptor protein complex 1 that plays a role in protein sorting in the late-Golgi/trans-Golgi network (TGN) and/or endosomes. The AP complexes mediate both the recruitment of clathrin to membranes and the recognition of sorting signals within the cytosolic tails of transmembrane cargo molecules. In association with AFTPH/aftiphilin in the aftiphilin/p200/gamma-synergin complex, involved in the trafficking of transferrin from early to recycling endosomes, and the membrane trafficking of furin and the lysosomal enzyme cathepsin D between the trans-Golgi network (TGN) and endosomes.", "evidence": [ { "database": "UniProtKB", "id": "A0AAA9TSD9", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TSD9#function" }, { "database": "UniProtKB", "id": "ARBA00054430", "url": "https://www.uniprot.org/uniprotkb/ARBA00054430#function" }, { "database": "UniProtKB", "id": "F1MF68", "url": "https://www.uniprot.org/uniprotkb/F1MF68#function" }, { "database": "UniProtKB", "id": "A0AAA9THQ8", "url": "https://www.uniprot.org/uniprotkb/A0AAA9THQ8#function" }, { "database": "UniProtKB", "id": "G3MZH4", "url": "https://www.uniprot.org/uniprotkb/G3MZH4#function" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Bos taurus", "taxid": 9913, "evidence": [ { "database": "UniProtKB", "id": "A0AAA9TSD9", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TSD9" } ], "common_name": "Bovine", "glygen_name": "Bovine", "reference_species": "Bos taurus [9913]" } ], "gene": [ { "name": "AP1G1", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TSD9", "locus": { "chromosome": "18", "start_pos": 39350490, "end_pos": 39252673, "strand": "-", "evidence": [ { "database": "Ensembl Gene", "id": "ENSBTAG00000002769", "url": "https://www.ensembl.org/id/ENSBTAG00000002769" } ] } } ], "crossref": [ { "id": "A0AAA9TSD9", "url": "https://alphafold.ebi.ac.uk/entry/A0AAA9TSD9", "database": "AlphaFoldDB", "categories": [] }, { "id": "ENSBTAG00000002769", "url": "https://bgee.org/?page=gene&gene_id=ENSBTAG00000002769", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "IPR002553", "url": "https://www.ebi.ac.uk/interpro/entry/IPR002553", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR008152", "url": "https://www.ebi.ac.uk/interpro/entry/IPR008152", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR008153", "url": "https://www.ebi.ac.uk/interpro/entry/IPR008153", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR011989", "url": "https://www.ebi.ac.uk/interpro/entry/IPR011989", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR013041", "url": "https://www.ebi.ac.uk/interpro/entry/IPR013041", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR016024", "url": "https://www.ebi.ac.uk/interpro/entry/IPR016024", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR017107", "url": "https://www.ebi.ac.uk/interpro/entry/IPR017107", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR050840", "url": "https://www.ebi.ac.uk/interpro/entry/IPR050840", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "F1MF68", "url": "https://www.orthodb.org/?gene=F1MF68", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "G3MZH4", "url": "https://www.orthodb.org/?gene=G3MZH4", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR22780", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR22780", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF01602", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF01602", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF02883", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF02883", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "A0AAA9THQ8", "url": "https://www.uniprot.org/uniprotkb/A0AAA9THQ8", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0AAA9THQ8-1", "url": "https://www.uniprot.org/uniprotkb/A0AAA9THQ8-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0AAA9TSD9", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TSD9", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0AAA9TSD9-1", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TSD9-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "F1MF68", "url": "https://www.uniprot.org/uniprotkb/F1MF68", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "F1MF68-1", "url": "https://www.uniprot.org/uniprotkb/F1MF68-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "G3MZH4", "url": "https://www.uniprot.org/uniprotkb/G3MZH4", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "G3MZH4-1", "url": "https://www.uniprot.org/uniprotkb/G3MZH4-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MVHLEGNSGWRKIGSWPWIVKIYSKGIISRMPAPIRLRELIRTIRTARTQAEEREMIQKECAAIRSSFREEDNTYRCRNVAKLLYMHMLGYPAHFGQLECLKLIASQKFTDKRIGYLGAMLLLDERQDVHLLMTNCIKNDLNHSTQYVQGLALCTLGCMGSSEMCRDLAGEVEKLLKTSNSYLRKKAALCAVHVIRKVPELMEMFLPATKNLLNEKNHGVLHTSVVLLTEMCERSPDMLAHFRKLVPQLVRILKNLIMSGYSPEHDVSGISDPFLQVRILRLLRILGRNDDDSSEAMNDILAQVATNTETSKNVGNAILYETVLTIMDIKSESGLRVLAINILGRFLLNNDKNIRYVALTSLLKTVQTDHNAVQRHRSTIVDCLKDLDVSIKRRAMELSFALVNGNNIRGMMKELLYFLDSCEPEFKADCASGIFLAAEKYAPSKRWHIDTIMRVLTTAGSYVRDDAVPNLIQLITNSVEMHAYTVQRLYKAILGDYSQQPLVQVAAWCIGEYGDLLVSGQCEEEEPIQVTEDEVLDILESVLISNMSTSVTRGYALTAIMKLSTRFTCTVNRIKKVVSIYGSSIDVELQQRAVEYNALFKKYDHMRSALLERMPVMEKVTTNGPTEIVQTNGETDPTPLETKPPPSGPQPTSQANDLLDLLGGNDITPVIPTAPTSKPASAGGELLDLLGDINLTGAPAAAPAPASVPQISQPPFLLDGLSSQPLFNDIATGIPSITAYSKNGLKIEFTFERSNTNPSVTVITIQASNSTELDMTDFVFQAAVPKTFQLQLLSPSSSIVPAFNTGTITQVIKVLNPQKQQLRMRIKLTYNHKGSAMQDLAEVNNFPPQSWQ", "length": 852, "header": "tr|A0AAA9TSD9-1|A0AAA9TSD9_BOVIN Isoform 1 of AP-1 complex subunit gamma OS=Bos taurus OX=9913 GN=AP1G1 PE=3 SV=1 CANONICAL=A0AAA9TSD9-1" }, "isoforms": [ { "isoform_ac": "A0AAA9THQ8-1", "url": "https://www.uniprot.org/uniprotkb/A0AAA9THQ8/entry", "sequence": { "sequence": "MYLAGEAWSPNQWITRQFLVLRMPAPIRLRELIRTIRTARTQAEEREMIQKECAAIRSSFREEDNTYRCRNVAKLLYMHMLGYPAHFGQLECLKLIASQKFTDKRIGYLGAMLLLDERQDVHLLMTNCIKNDLNHSTQYVQGLALCTLGCMGSSEMCRDLAGEVEKLLKTSNSYLRKKAALCAVHVIRKVPELMEMFLPATKNLLNEKNHGVLHTSVVLLTEMCERSPDMLAHFRKNEKLVPQLVRILKNLIMSGYSPEHDVSGISDPFLQVRILRLLRILGRNDDDSSEAMNDILAQVATNTETSKNVGNAILYETVLTIMDIKSESGLRVLAINILGRFLLNNDKNIRYVALTSLLKTVQTDHNAVQRHRSTIVDCLKDLDVSIKRRAMELSFALVNGNNIRGMMKELLYFLDSCEPEFKADCASGIFLAAEKYAPSKRWHIDTIMRVLTTAGSYVRDDAVPNLIQLITNSVEMHAYTVQRLYKAILGDYSQQPLVQVAAWCIGEYGDLLVSGQCEEEEPIQVTEDEVLDILESVLISNMSTSVTRGYALTAIMKLSTRFTCTVNRIKKVVSIYGSSIDVELQQRAVEYNALFKKYDHMRSALLERMPVMEKVTTNGPTEIVQTNGETDPTPLETKPPPSGPQPTSQANDLLDLLGGNDITPVIPTAPTSKPASAGGELLDLLGDINLTGAPAAAPAPASVPQISQPPFLLDGLSSQPLFNDIATGIPSITAYSKNGLKIEFTFERSNTNPSVTVITIQASNSTELDMTDFVFQAAVPKTFQLQLLSPSSSIVPAFNTGTITQVIKVLNPQKQQLRMRIKLTYNHKGSAMQDLAEVNNFPPQSWQ", "length": 847, "header": "tr|A0AAA9THQ8-1|A0AAA9TSD9_BOVIN Computationally mapped isoform of AP-1 complex subunit gamma OS=Bos taurus OX=9913 GN=AP1G1 PE=3 SV=2 CANONICAL=A0AAA9TSD9-1" }, "locus": { "chromosome": "18", "start_pos": 39346406, "end_pos": 39258501, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000113139.2", "url": "https://www.ensembl.org/id/ENSBTAT00000113139.2" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000095741.2", "url": "https://www.ensembl.org/id/ENSBTAP00000095741.2" } ] } }, { "isoform_ac": "A0AAA9TSD9-1", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TSD9/entry", "sequence": { "sequence": "MVHLEGNSGWRKIGSWPWIVKIYSKGIISRMPAPIRLRELIRTIRTARTQAEEREMIQKECAAIRSSFREEDNTYRCRNVAKLLYMHMLGYPAHFGQLECLKLIASQKFTDKRIGYLGAMLLLDERQDVHLLMTNCIKNDLNHSTQYVQGLALCTLGCMGSSEMCRDLAGEVEKLLKTSNSYLRKKAALCAVHVIRKVPELMEMFLPATKNLLNEKNHGVLHTSVVLLTEMCERSPDMLAHFRKLVPQLVRILKNLIMSGYSPEHDVSGISDPFLQVRILRLLRILGRNDDDSSEAMNDILAQVATNTETSKNVGNAILYETVLTIMDIKSESGLRVLAINILGRFLLNNDKNIRYVALTSLLKTVQTDHNAVQRHRSTIVDCLKDLDVSIKRRAMELSFALVNGNNIRGMMKELLYFLDSCEPEFKADCASGIFLAAEKYAPSKRWHIDTIMRVLTTAGSYVRDDAVPNLIQLITNSVEMHAYTVQRLYKAILGDYSQQPLVQVAAWCIGEYGDLLVSGQCEEEEPIQVTEDEVLDILESVLISNMSTSVTRGYALTAIMKLSTRFTCTVNRIKKVVSIYGSSIDVELQQRAVEYNALFKKYDHMRSALLERMPVMEKVTTNGPTEIVQTNGETDPTPLETKPPPSGPQPTSQANDLLDLLGGNDITPVIPTAPTSKPASAGGELLDLLGDINLTGAPAAAPAPASVPQISQPPFLLDGLSSQPLFNDIATGIPSITAYSKNGLKIEFTFERSNTNPSVTVITIQASNSTELDMTDFVFQAAVPKTFQLQLLSPSSSIVPAFNTGTITQVIKVLNPQKQQLRMRIKLTYNHKGSAMQDLAEVNNFPPQSWQ", "length": 852, "header": "tr|A0AAA9TSD9-1|A0AAA9TSD9_BOVIN Isoform 1 of AP-1 complex subunit gamma OS=Bos taurus OX=9913 GN=AP1G1 PE=3 SV=1 CANONICAL=A0AAA9TSD9-1" }, "locus": { "chromosome": "18", "start_pos": 39346406, "end_pos": 39290436, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000120570.1", "url": "https://www.ensembl.org/id/ENSBTAT00000120570.1" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000099950.1", "url": "https://www.ensembl.org/id/ENSBTAP00000099950.1" } ] } }, { "isoform_ac": "F1MF68-1", "url": "https://www.uniprot.org/uniprotkb/F1MF68/entry", "sequence": { "sequence": "MRMPAPIRLRELIRTIRTARTQAEEREMIQKECAAIRSSFREEDNTYRCRNVAKLLYMHMLGYPAHFGQLECLKLIASQKFTDKRIGYLGAMLLLDERQDVHLLMTNCIKNDLNHSTQYVQGLALCTLGCMGSSEMCRDLAGEVEKLLKTSNSYLRKKAALCAVHVIRKVPELMEMFLPATKNLLNEKNHGVLHTSVVLLTEMCERSPDMLAHFRKLVPQLVRILKNLIMSGYSPEHDVSGISDPFLQVRILRLLRILGRNDDDSSEAMNDILAQVATNTETSKNVGNAILYETVLTIMDIKSESGLRVLAINILGRFLLNNDKNIRYVALTSLLKTVQTDHNAVQRHRSTIVDCLKDLDVSIKRRAMELSFALVNGNNIRGMMKELLYFLDSCEPEFKADCASGIFLAAEKYAPSKRWHIDTIMRVLTTAGSYVRDDAVPNLIQLITNSVEMHAYTVQRLYKAILGDYSQQPLVQVAAWCIGEYGDLLVSGQCEEEEPIQVTEDEVLDILESVLISNMSTSVTRGYALTAIMKLSTRFTCTVNRIKKVVSIYGSSIDVELQQRAVEYNALFKKYDHMRSALLERMPVMEKVTTNGPTEIVQTNGETDPTPLETKPPPSGPQPTSQANDLLDLLGGNDITPVIPTAPTSKPASAGGELLDLLGDINLTGAPAAAPAPASVPQISQPPFLLDGLSSQPLFNDIATGIPSITAYSKNGLKIEFTFERSNTNPSVTVITIQASNSTELDMTDFVFQAAVPKTFQLQLLSPSSSIVPAFNTGTITQVIKVLNPQKQQLRMRIKLTYNHKGSAMQDLAEVNNFPPQSWQ", "length": 824, "header": "tr|F1MF68-1|F1MF68_BOVIN Computationally mapped isoform of AP-1 complex subunit gamma OS=Bos taurus OX=9913 GN=AP1G1 PE=3 SV=3 CANONICAL=A0AAA9TSD9-1" }, "locus": { "chromosome": "18", "start_pos": 39346406, "end_pos": 39260616, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000003599.7", "url": "https://www.ensembl.org/id/ENSBTAT00000003599.7" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000003599.6", "url": "https://www.ensembl.org/id/ENSBTAP00000003599.6" } ] } }, { "isoform_ac": "G3MZH4-1", "url": "https://www.uniprot.org/uniprotkb/G3MZH4/entry", "sequence": { "sequence": "MYLAGEAWSPNQWITRQFLVLRMPAPIRLRELIRTIRTARTQAEEREMIQKECAAIRSSFREEDNTYRCRNVAKLLYMHMLGYPAHFGQLECLKLIASQKFTDKRIGYLGAMLLLDERQDVHLLMTNCIKNDLNHSTQYVQGLALCTLGCMGSSEMCRDLAGEVEKLLKTSNSYLRKKAALCAVHVIRKVPELMEMFLPATKNLLNEKNHGVLHTSVVLLTEMCERSPDMLAHFRKLVPQLVRILKNLIMSGYSPEHDVSGISDPFLQVRILRLLRILGRNDDDSSEAMNDILAQVATNTETSKNVGNAILYETVLTIMDIKSESGLRVLAINILGRFLLNNDKNIRYVALTSLLKTVQTDHNAVQRHRSTIVDCLKDLDVSIKRRAMELSFALVNGNNIRGMMKELLYFLDSCEPEFKADCASGIFLAAEKYAPSKRWHIDTIMRVLTTAGSYVRDDAVPNLIQLITNSVEMHAYTVQRLYKAILGDYSQQPLVQVAAWCIGEYGDLLVSGQCEEEEPIQVTEDEVLDILESVLISNMSTSVTRGYALTAIMKLSTRFTCTVNRIKKVVSIYGSSIDVELQQRAVEYNALFKKYDHMRSALLERMPVMEKVTTNGPTEIVQTNGETDPTPLETKPPPSGPQPTSQANDLLDLLGGNDITPVIPTAPTSKPASAGGELLDLLGDINLTGIPSITAYSKNGLKIEFTFERSNTNPSVTVITIQASNSTELDMTDFVFQAAVPKTFQLQLLSPSSSIVPAFNTGTITQVIKVLNPQKQQLRMRIKLTYNHKGSAMQDLAEVNNFPPQSWQ", "length": 808, "header": "tr|G3MZH4-1|G3MZH4_BOVIN Computationally mapped isoform of AP-1 complex subunit gamma OS=Bos taurus OX=9913 GN=AP1G1 PE=3 SV=3 CANONICAL=A0AAA9TSD9-1" }, "locus": { "chromosome": "18", "start_pos": 39346406, "end_pos": 39258501, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000065037.4", "url": "https://www.ensembl.org/id/ENSBTAT00000065037.4" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000054971.3", "url": "https://www.ensembl.org/id/ENSBTAP00000054971.3" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [], "orthologs": [], "go_annotation": { "categories": [ { "name": "Biological Process", "total": 5, "go_terms": [ { "name": "intracellular protein transport", "id": "GO:0006886", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006886", "evidence": [ { "database": "UniProtKB", "id": "A0AAA9TSD9", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TSD9" } ], "pmid": "" }, { "name": "vesicle-mediated transport", "id": "GO:0016192", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016192", "evidence": [ { "database": "UniProtKB", "id": "A0AAA9TSD9", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TSD9" } ], "pmid": "" }, { "name": "endosome to melanosome transport", "id": "GO:0035646", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0035646", "evidence": [ { "database": "UniProtKB", "id": "A0AAA9TSD9", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TSD9" } ], "pmid": "" }, { "name": "Golgi to lysosome transport", "id": "GO:0090160", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0090160", "evidence": [ { "database": "UniProtKB", "id": "A0AAA9TSD9", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TSD9" } ], "pmid": "" }, { "name": "positive regulation of natural killer cell degranulation", "id": "GO:0043323", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0043323", "evidence": [ { "database": "UniProtKB", "id": "A0AAA9TSD9", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TSD9" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 6, "go_terms": [ { "name": "AP-1 adaptor complex", "id": "GO:0030121", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030121", "evidence": [ { "database": "UniProtKB", "id": "A0AAA9TSD9", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TSD9" } ], "pmid": "" }, { "name": "cytosol", "id": "GO:0005829", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005829", "evidence": [ { "database": "UniProtKB", "id": "A0AAA9TSD9", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TSD9" } ], "pmid": "" }, { "name": "clathrin-coated pit", "id": "GO:0005905", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005905", "evidence": [ { "database": "UniProtKB", "id": "A0AAA9TSD9", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TSD9" } ], "pmid": "" }, { "name": "perinuclear region of cytoplasm", "id": "GO:0048471", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0048471", "evidence": [ { "database": "UniProtKB", "id": "A0AAA9TSD9", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TSD9" } ], "pmid": "" }, { "name": "recycling endosome", "id": "GO:0055037", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0055037", "evidence": [ { "database": "UniProtKB", "id": "A0AAA9TSD9", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TSD9" } ], "pmid": "" }, { "name": "trans-Golgi network", "id": "GO:0005802", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005802", "evidence": [ { "database": "UniProtKB", "id": "A0AAA9TSD9", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TSD9" } ], "pmid": "" } ] }, { "name": "Molecular Function", "total": 3, "go_terms": [ { "name": "small GTPase binding", "id": "GO:0031267", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0031267", "evidence": [ { "database": "UniProtKB", "id": "A0AAA9TSD9", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TSD9" } ], "pmid": "" }, { "name": "kinesin binding", "id": "GO:0019894", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0019894", "evidence": [ { "database": "UniProtKB", "id": "A0AAA9TSD9", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TSD9" } ], "pmid": "" }, { "name": "GTP-dependent protein binding", "id": "GO:0030742", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030742", "evidence": [ { "database": "UniProtKB", "id": "A0AAA9TSD9", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TSD9" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 142, "end_pos": 144, "annotation": "n_glycosylation_sequon" }, { "start_pos": 546, "end_pos": 548, "annotation": "n_glycosylation_sequon" }, { "start_pos": 694, "end_pos": 696, "annotation": "n_glycosylation_sequon" }, { "start_pos": 769, "end_pos": 771, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A0AAA9TSD9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TSD9" }, { "id": "PS50180", "database": "PROSITE", "url": "https://prosite.expasy.org/PS50180" } ], "ann_type": 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Classification" ] }, { "id": "G3N2R0", "url": "https://www.orthodb.org/?gene=G3N2R0", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR19957", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR19957", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR19957:SF30", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR19957:SF30", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00804", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00804", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF05739", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF05739", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "XP_024852557", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_024852557", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0AAA9SQ72", "url": "https://www.uniprot.org/uniprotkb/A0AAA9SQ72", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0AAA9SQ72-1", "url": "https://www.uniprot.org/uniprotkb/A0AAA9SQ72-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0AAA9TUZ8", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TUZ8", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0AAA9TUZ8-1", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TUZ8-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "G3N2R0", "url": "https://www.uniprot.org/uniprotkb/G3N2R0", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "G3N2R0-1", "url": "https://www.uniprot.org/uniprotkb/G3N2R0-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MELPQGDEMDDEVKKKTTSQPQSKMKDRLGELVELTKQFDQQFPDDDDDFDSPHEDIVFETDHILESLYRDIQDLQEENQHLIADVRRLGKQNTRFLTSMRRLSSIKRDTNSIGKDIKARGESINRKLGAMKALSEQAEVQHGAHSAVARIARAQYSALACIFQAAMHEYNCAEMKQRENCKIRIQRQLEIMGKDVSGDEIEDMFEQGKWDVFSENLLADVKGARAALNEIESRHRELLQLEGRIRDLHDLFLQMALLVEQQADTLDVIEFNVQKTVEYTGQAKVQVRKAVQYKKKNPCRTICCFCCPCLN", "length": 311, "header": "tr|A0AAA9TUZ8-1|A0AAA9TUZ8_BOVIN Isoform 1 of Syntaxin-11 OS=Bos taurus OX=9913 GN=STX11 PE=3 SV=1 CANONICAL=A0AAA9TUZ8-1" }, "isoforms": [ { "isoform_ac": "A0AAA9SQ72-1", "url": "https://www.uniprot.org/uniprotkb/A0AAA9SQ72/entry", "sequence": { "sequence": "MNCSAGKMKDRLGELVELTKQFDQQFPDDDDDFDSPHEDIVFETDHILESLYRDIQDLQEENQHLIADVRRLGKQNTRFLTSMRRLSSIKRDTNSIGKDIKARGESINRKLGAMKALSEQAEVQHGAHSAVARIARAQYSALACIFQAAMHEYNCAEMKQRENCKIRIQRQLEIMGKDVSGDEIEDMFEQGKWDVFSENLLADVKGARAALNEIESRHRELLQLEGRIRDLHDLFLQMALLVEQQADTLDVIEFNVQKTVEYTGQAKVQVRKAVQYKKKNPCRTICCFCCPCLN", "length": 294, "header": "tr|A0AAA9SQ72-1|A0AAA9TUZ8_BOVIN Computationally mapped isoform of Syntaxin-11 OS=Bos taurus OX=9913 GN=STX11 PE=3 SV=1 CANONICAL=A0AAA9TUZ8-1" }, "locus": { "chromosome": "9", "start_pos": 81573471, "end_pos": 81549776, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000104603.1", "url": "https://www.ensembl.org/id/ENSBTAT00000104603.1" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000086139.1", "url": "https://www.ensembl.org/id/ENSBTAP00000086139.1" } ] } }, { "isoform_ac": "A0AAA9TUZ8-1", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TUZ8/entry", "sequence": { "sequence": "MELPQGDEMDDEVKKKTTSQPQSKMKDRLGELVELTKQFDQQFPDDDDDFDSPHEDIVFETDHILESLYRDIQDLQEENQHLIADVRRLGKQNTRFLTSMRRLSSIKRDTNSIGKDIKARGESINRKLGAMKALSEQAEVQHGAHSAVARIARAQYSALACIFQAAMHEYNCAEMKQRENCKIRIQRQLEIMGKDVSGDEIEDMFEQGKWDVFSENLLADVKGARAALNEIESRHRELLQLEGRIRDLHDLFLQMALLVEQQADTLDVIEFNVQKTVEYTGQAKVQVRKAVQYKKKNPCRTICCFCCPCLN", "length": 311, "header": "tr|A0AAA9TUZ8-1|A0AAA9TUZ8_BOVIN Isoform 1 of Syntaxin-11 OS=Bos taurus OX=9913 GN=STX11 PE=3 SV=1 CANONICAL=A0AAA9TUZ8-1" }, "locus": { "chromosome": "9", "start_pos": 81573471, "end_pos": 81524365, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000096305.1", "url": "https://www.ensembl.org/id/ENSBTAT00000096305.1" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000100408.1", "url": "https://www.ensembl.org/id/ENSBTAP00000100408.1" } ] } }, { "isoform_ac": "G3N2R0-1", "url": "https://www.uniprot.org/uniprotkb/G3N2R0/entry", "sequence": { "sequence": "MKDRLGELVELTKQFDQQFPDDDDDFDSPHEDIVFETDHILESLYRDIQDLQEENQHLIADVRRLGKQNTRFLTSMRRLSSIKRDTNSIGKDIKARGESINRKLGAMKALSEQAEVQHGAHSAVARIARAQYSALACIFQAAMHEYNCAEMKQRENCKIRIQRQLEIMGKDVSGDEIEDMFEQGKWDVFSENLLADVKGARAALNEIESRHRELLQLEGRIRDLHDLFLQMALLVEQQADTLDVIEFNVQKTVEYTGQAKVQVRKAVQYKKKNPCRTICCFCCPCLN", "length": 287, "header": "tr|G3N2R0-1|G3N2R0_BOVIN Computationally mapped isoform of Syntaxin-11 OS=Bos taurus OX=9913 GN=STX11 PE=3 SV=3 CANONICAL=A0AAA9TUZ8-1" }, "locus": { "chromosome": "9", "start_pos": 81573471, "end_pos": 81572611, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000122163.1", "url": "https://www.ensembl.org/id/ENSBTAT00000122163.1" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000095399.1", "url": "https://www.ensembl.org/id/ENSBTAP00000095399.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [ { "id": "bta:539960", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?bta:539960", "resource": "KEGG Pathway" } ], "orthologs": [ { "uniprot_canonical_ac": "A0A0G2K516-1", "protein_name": "Syntaxin-11", "gene_name": "Stx11", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MKDRLAELQELSRSYDQQFPDGDDDFDAPQEDIVFETDHILESLYRVIQDIQDENQLLLIDVRRLGRQNVRFLTSMRRLSSIKRDTNSIAKAIKTRGEGIHQKLRSMKEMSEQAEAQHGAHSAVARISHAQYSALARAFQQAMYEYNQAEMKQRDNCKIRIQRQLEIMGKDVSGEQIEDMFEQGKWDVFSENLLADVKGARAALNEIESRHRELLRLEGRIRDVHELFLQMAVLVEKQADTLNVIELNVQKTLDYTGEAKAQVRKAVQYKKKNPCRTICCFCCPCVN", "length": 287 }, "evidence": [ { "id": "A0AAA9TUZ8", "url": "https://omabrowser.org/oma/group/A0AAA9TUZ8/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "E1BUT0-1", "protein_name": "Syntaxin-11", "gene_name": "STX11", "tax_id": 9031, "organism": "Gallus gallus", "sequence": { "sequence": "MKDRLNEMRELARLHNQEFSYSEDDENSPRDILLYETDYALETLHKDIENIRTENNLLKEDVKRLKKQNNRFLTSMRRLSSIKRDTNGIARDIKARGESIHRKLQIMRDFCEDAITKYGVMSVIARVAKNHYVDLMHAFQEAMFEYNATEMNQRENCKIRIQRQLEIMGKDVSSNQIEEMIEQGRWDVFSENLLSDVKGARSALNEIETRHKELVKLEGRIKEVHELFLQVALLVEEQADTFDVIEINVQNVEDYVGESKEQIKKALEYRRKHPLMTILCCCFSYCRR", "length": 288 }, "evidence": [ { "id": "A0AAA9TUZ8", "url": "https://omabrowser.org/oma/group/A0AAA9TUZ8/", "database": "OMA" } ], "glygen_name": "Chicken", "common_name": "Chicken" }, { "uniprot_canonical_ac": "F1S731-1", "protein_name": "Syntaxin-11", "gene_name": "STX11", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MKDRLVELLELTKHYDQQFPEKDDDFDSPHEDIVFETDHILESLYRDIQELQDENQQLFTDVKRLGKQNARFLTSMRRLSSIKRDTNSIAKDIKARGESIHRKLSAMKALSEEAQAKHGEHSAVARIAQAQYSALARTFQAAMHEYNQAEMKQRENCKIRIQRQLEIMGKDVSSNQIEDMFEQGKWDVFSENLLADVKGARAALNEIENRHREMLRLESRIRDLHDLFLQMAMLVEQQADTLDVIEFNVQKTLDYTGQAKVQVRKAVQYKKKNPCRTICCFCCPCLN", "length": 287 }, "evidence": [ { "id": "A0AAA9TUZ8", "url": "https://omabrowser.org/oma/group/A0AAA9TUZ8/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "G3H6X5-1", "protein_name": "Syntaxin-11", "gene_name": "Stx11", "tax_id": 10029, "organism": "Cricetulus griseus", "sequence": { "sequence": "MKDRLAELLELSRSYDQQFPDGDDDFDTPQEDIVFETDHILESLYRVIQDIQDENQLLMIDVKRLGRQNVRFLTSMRRLSSIKRDTNSIAKAIKTRGEGIHQKLRSMKELSDQAEVQHGSHSAVARISHAQYSALTRAFQQAMYEYNQAEMKQRDNCKIRIQRQLEIMGKDVSGEQIEDMFEQGKWDVFSENLLADVKGARAALNEIESRHRELLRLEGRIRDVHELFLQMAVLVEKQADTLNVIELNVQKTLDYTGEAKAQVRKAVQYKKKNPCRTICCFCCPCVN", "length": 287 }, "evidence": [ { "id": "A0AAA9TUZ8", "url": "https://omabrowser.org/oma/group/A0AAA9TUZ8/", "database": "OMA" } ], "glygen_name": "Hamster", "common_name": "Chinese hamster" }, { "uniprot_canonical_ac": "O75558-1", "protein_name": "Syntaxin-11", "gene_name": "STX11", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MKDRLAELLDLSKQYDQQFPDGDDEFDSPHEDIVFETDHILESLYRDIRDIQDENQLLVADVKRLGKQNARFLTSMRRLSSIKRDTNSIAKAIKARGEVIHCKLRAMKELSEAAEAQHGPHSAVARISRAQYNALTLTFQRAMHDYNQAEMKQRDNCKIRIQRQLEIMGKEVSGDQIEDMFEQGKWDVFSENLLADVKGARAALNEIESRHRELLRLESRIRDVHELFLQMAVLVEKQADTLNVIELNVQKTVDYTGQAKAQVRKAVQYEEKNPCRTLCCFCCPCLK", "length": 287 }, "evidence": [ { "id": "A0AAA9TUZ8", "url": "https://omabrowser.org/oma/group/A0AAA9TUZ8/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "Q9D3G5-1", "protein_name": "Syntaxin-11", "gene_name": "Stx11", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MKDRLAELQELSRSYDQQFPDGDNDFDAPREDIVFETDNILESLYRVIQDIQDENQLLLIDVRRLGRQNVRFLTSMRRLSSIKRDTNSIAKAIKTRGEGIHQKLRSMKELSEQAEARHGAHSAVARISHAQYSALARAFQQAMYEYNQAEMKQRDNCKIRIQRQLEIMGKDMSGEQIEDMFEQGKWDVFSENLLADLKGARAALNEIESRHRELLRLEGRIRDVHELFLQMAVLVEKQEDTLNVIELNVQKTLDYTGEAKAQVRKAVQYKKKNPCRTICCFCCPCVN", "length": 287 }, "evidence": [ { "id": "A0AAA9TUZ8", "url": "https://omabrowser.org/oma/group/A0AAA9TUZ8/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" } ], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 2, "go_terms": [ { "name": "Golgi apparatus", "id": "GO:0005794", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005794", "evidence": [ { "database": "UniProtKB", "id": "A0AAA9TUZ8", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TUZ8" } ], "pmid": "" }, { "name": "membrane", "id": "GO:0016020", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016020", "evidence": [ { "database": "UniProtKB", "id": "A0AAA9TUZ8", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TUZ8" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 2, "go_terms": [ { "name": "intracellular protein transport", "id": "GO:0006886", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006886", "evidence": [ { "database": "UniProtKB", "id": "A0AAA9TUZ8", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TUZ8" } ], "pmid": "" }, { "name": "vesicle-mediated transport", "id": "GO:0016192", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016192", "evidence": [ { "database": "UniProtKB", "id": "A0AAA9TUZ8", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TUZ8" } ], "pmid": "" } ] }, { "name": "Molecular Function", "total": 1, "go_terms": [ { "name": "SNAP receptor activity", "id": "GO:0005484", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005484", "evidence": [ { "database": "UniProtKB", "id": "A0AAA9TUZ8", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TUZ8" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A0AAA9TUZ8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TUZ8" }, { "id": "PS50192", "database": "PROSITE", "url": "https://prosite.expasy.org/PS50192" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "T-SNARE coiled-coil homology", "eco_id": "ECO_0000259", "start_pos": 228, "end_pos": 290, "start_aa": "Leu", "end_aa": "Ala", "glycosite_overlap": [] } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" }, { "name": "homologset.oma", "label": "OMA Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ], "tool_support": { "graph_view": "yes" } }, { "uniprot_canonical_ac": "A0AAA9TV36-1", "uniprot_ac": "A0AAA9TV36", "uniprot_id": "A0AAA9TV36_BOVIN", "mass": { "chemical_mass": 143083.0, "monoisotopic_mass": 143083.0 }, "refseq": {}, "gene_names": [ { "name": "FLII", "type": "recommended", "evidence": [ { "id": "A0AAA9TV36", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TV36" } ] } ], "protein_names": [ { "name": "FLII actin remodeling protein", "type": "synonym", "evidence": [ { "id": "A0AAA9TV36", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TV36/entry#names_and_taxonomy" } ] } ], "function": [ { "annotation": "Is a regulator of actin polymerization, required for proper myofibril organization and regulation of the length of sarcomeric thin filaments. It also plays a role in the assembly of cardiomyocyte cell adhesion complexes. Regulates cytoskeletal rearrangements involved in cytokinesis and cell migration, by inhibiting Rac1-dependent paxillin phosphorylation. May play a role as coactivator in transcriptional activation by hormone-activated nuclear receptors (NR) and acts in cooperation with NCOA2 and CARM1. Involved in estrogen hormone signaling.", "evidence": [ { "database": "UniProtKB", "id": "A0AAA9T1C8", "url": "https://www.uniprot.org/uniprotkb/A0AAA9T1C8#function" }, { "database": "UniProtKB", "id": "ARBA00055276", "url": "https://www.uniprot.org/uniprotkb/ARBA00055276#function" }, { "database": "UniProtKB", "id": "A0AAA9TC31", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TC31#function" }, { "database": "UniProtKB", "id": "A0AAA9TV36", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TV36#function" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Bos taurus", "taxid": 9913, "evidence": [ { "database": "UniProtKB", "id": "A0AAA9TV36", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TV36" } ], "common_name": "Bovine", "glygen_name": "Bovine", "reference_species": "Bos taurus [9913]" } ], "gene": [ { "name": "FLII", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TV36", "locus": { "chromosome": "19", "start_pos": 34399727, "end_pos": 34386692, "strand": "-", "evidence": [ { "database": "Ensembl Gene", "id": "ENSBTAG00000016161", "url": "https://www.ensembl.org/id/ENSBTAG00000016161" } ] } } ], "crossref": [ { "id": "A0AAA9TV36", "url": "https://alphafold.ebi.ac.uk/entry/A0AAA9TV36", "database": "AlphaFoldDB", "categories": [] }, { "id": "cd11280", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd11280", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "cd11288", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd11288", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "cd11290", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd11290", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "cd11291", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd11291", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "cd11292", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd11292", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "514446", "url": "https://www.ncbi.nlm.nih.gov/gene/514446", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR001611", "url": "https://www.ebi.ac.uk/interpro/entry/IPR001611", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR003591", "url": "https://www.ebi.ac.uk/interpro/entry/IPR003591", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR007122", "url": "https://www.ebi.ac.uk/interpro/entry/IPR007122", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR007123", "url": "https://www.ebi.ac.uk/interpro/entry/IPR007123", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR029006", "url": "https://www.ebi.ac.uk/interpro/entry/IPR029006", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR032675", "url": "https://www.ebi.ac.uk/interpro/entry/IPR032675", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR055414", "url": "https://www.ebi.ac.uk/interpro/entry/IPR055414", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "PTHR11977", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR11977", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR11977:SF51", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR11977:SF51", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00626", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00626", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF13855", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF13855", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF23598", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF23598", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "A0AAA9T1C8", "url": "https://www.uniprot.org/uniprotkb/A0AAA9T1C8", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0AAA9T1C8-1", "url": "https://www.uniprot.org/uniprotkb/A0AAA9T1C8-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0AAA9TC31", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TC31", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0AAA9TC31-1", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TC31-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0AAA9TV36", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TV36", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0AAA9TV36-1", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TV36-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "DVPGLRPAPGGYFPENVKAMTSLRWLKLNRTGLCYLPEELASLQKLEHLSVSHNNLTTLHGELSSLPSLRAIVARANSLKNSGVPDDIFKLDDLSVLDLSYNQLTECPRELENAKNMLVLNLSHNSIDSIPNQLFINLTDLLYLDLSENRLESLPPQMRRLVHLQTLVLNGNPLLHAQLRQLPALTALQTLHLRNTQRTQSNLPTSLEGLSHLADVDLSCNDLTRVPECLYALPGLRRLNLSSNQIAELSLCIDQWVHLETLNLSRNQLTSLPSAICKLTKLKRLYLNSNQLDFDGLPSGIGKLSSLEEFMAANNKLELIPESLCRCTKLRKLVLNKNRLVTLPEAIHFLTEIEVLDVRENPSLVMPPKPVDRAAEWYNIDFSLQNQLRLAGASPATVAAAAAAGSGPKDPLARKMRLRRRKDSAQDDQAKQVLKGMSDVAQEKNRKQEESAEAGAPGGKVRRWDQGLEKPRLDYSEFFTEDVGQLPGLTIWQIENFVPVLVEEDLHGKFYEADCYIVLKTFLDDSGSLNWEIYYWIGGEATLDKKACSAIHAVNLRNYLGAECRTVREEMGDESEEFLQVFDNDISYIEGGTASGFYTVEDTHYVTRMYRVYGKKNIKLEPVPLKGASLDPRFVFLLDRGLDIYVWRGAQATLSSTTKARLFAEKINKNERKGKAEISLLVQGQEPPEFWETLGGEPSEIKKHVPDDFWPPQPKLYKVGLGLGYLELPQINYKLSVEHKKRPKVELMPRMRLLQSLLDTRCVYILDCWSDVFIWLGRKSPRLVRAAALKLGQELCGMLHRPRHAMVSRSLEGTEAQVFKAKFKNWDDVLSVDYTRNAEAMLQGPGLAGKVKRDAEKKDQMKADLTALFLPRQPPMALAEAEQLMEEWNEDLDGMEGFVLEGKKFARLPEEEFGHFYTQDCYVFLCRYWVPVEYEEEEKEEEKAGAEDKEGKEAAAEAEEKQPEEDFQCIVYFWQGREASNMGWLTFTFSLQKKFESLFPGKLEVVRMTQQQENPKFLSHFKRKFIIHRGKRKAAQGALQPSLYQIRTNGSALCTRCIQINTDSSLLNSEFCFILKVPFESEDNQGIVYAWVGRASDPDEAKLAEDILNSMFEASYSKQVINEGEEPENFFWVGIGAQKPYDDDAEYMKHTRLFRCSNEKGYFAVTEKCSDFCQDDLADDDIMLLDNGQEVYMWVGSQTSQVEIKLSLKACQVYIQHMRSKEHERPRRLRLVRKGNEQHAFTRCFHAWSTFRQALA", "length": 1256, "header": "tr|A0AAA9TV36-1|A0AAA9TV36_BOVIN Isoform 1 of FLII actin remodeling protein OS=Bos taurus OX=9913 GN=FLII PE=4 SV=1 CANONICAL=A0AAA9TV36-1" }, "isoforms": [ { "isoform_ac": "A0AAA9T1C8-1", "url": "https://www.uniprot.org/uniprotkb/A0AAA9T1C8/entry", "sequence": { "sequence": "MAEAKPHRPLLLARGVGLPAEAAHPAEPLHPVPAQEHLSVSHNNLTTLHGELSSLPSLRAIVARANSLKNSGVPDDIFKLDDLSVLDLSYNQLTECPRELENAKNMLVLNLSHNSIDSIPNQLFINLTDLLYLDLSENRLESLPPQMRRLVHLQTLVLNGNPLLHAQLRQLPALTALQTLHLRNTQRTQSNLPTSLEGLSHLADVDLSCNDLTRVPECLYALPGLRRLNLSSNQIAELSLCIDQWVHLETLNLSRNQLTSLPSAICKLTKLKRLYLNSNQLDFDGLPSGIGKLSSLEEFMAANNKLELIPESLCRCTKLRKLVLNKNRLVTLPEAIHFLTEIEVLDVRENPSLVMPPKPVDRAAEWYNIDFSLQNQLRLAGASPATVAAAAAAGSGPKDPLARKMRLRRRKDSAQDDQAKQVLKGMSDVAQEKNRKQEESAEAGAPGGKVRRWDQGLEKPRLDYSEFFTEDVGQLPGLTIWQIENFVPVLVEEDLHGKFYEADCYIVLKTFLDDSGSLNWEIYYWIGGEATLDKKACSAIHAVNLRNYLGAECRTVREEMGDESEEFLQVFDNDISYIEGGTASGFYTVEDTHYVTRMYRVYGKKNIKLEPVPLKGASLDPRFVFLLDRGLDIYVWRGAQATLSSTTKARLFAEKINKNERKGKAEISLLVQGQEPPEFWETLGGEPSEIKKHVPDDFWPPQPKLYKVGLGLGYLELPQINYKLSVEHKKRPKVELMPRMRLLQSLLDTRCVYILDCWSDVFIWLGRKSPRLVRAAALKLGQELCGMLHRPRHAMVSRSLEGTEAQVFKAKFKNWDDVLSVDYTRNAEAMLQGPGLAGKVKRDAEKKDQMKADLTALFLPRQPPMALAEAEQLMEEWNEDLDGMEGFVLEGKKFARLPEEEFGHFYTQDCYVFLCRYWVPVEYEEEEKEEEKAGAEDKEGKEAAAEAEEKQPEEDFQCIVYFWQGREASNMGWLTFTFSLQKKFESLFPGKLEVVRMTQQQENPKFLSHFKRKFIIHRGKRKAAQGALQPSLYQIRTNGSALCTRCIQINTDSSLLNSEFCFILKVPFESEDNQGIVYAWVGRASDPDEAKLAEDILNSMFEASYSKQVINEGEEPENFFWVGIGAQKPYDDDAEYMKHTRLFRCSNEKGYFAVTEKCSDFCQDDLADDDIMLLDNGQEVYMWVGSQTSQVEIKLSLKACQVYIQHMRSKEHERPRRLRLVRKGNEQHAFTRCFHAWSTFRQALA", "length": 1245, "header": "tr|A0AAA9T1C8-1|A0AAA9TV36_BOVIN Computationally mapped isoform of FLII actin remodeling protein OS=Bos taurus OX=9913 GN=FLII PE=4 SV=2 CANONICAL=A0AAA9TV36-1" }, "locus": { "chromosome": "19", "start_pos": 34398723, "end_pos": 34388507, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000121964.2", "url": "https://www.ensembl.org/id/ENSBTAT00000121964.2" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000089451.2", "url": "https://www.ensembl.org/id/ENSBTAP00000089451.2" } ] } }, { "isoform_ac": "A0AAA9TC31-1", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TC31/entry", "sequence": { "sequence": "MEGTGVLPFVRGVDLSGNDFKGGYFPENVKAMTSLRWLKLNRTGLCYLPEELASLQKLEHLSVSHNNLTTLHGELSSLPSLRAIVARANSLKNSGVPDDIFKLDDLSVLDLSYNQLTECPRELENAKNMLVLNLSHNRQLPALTALQTLHLRNTQRTQSNLPTSLEGLSHLADVDLSCNDLTRVPECLYALPGLRRLNLSSNQIAELSLCIDQWVHLETLNLSRNQLTSLPSAICKLTKLKRLYLNSNQLDFDGLPSGIGKLSSLEEFMAANNKLELIPESLCRCTKLRKLVLNKNRLVTLPEAIHFLTEIEVLDVRENPSLVMPPKPVDRAAEWYNIDFSLQNQLRLAGASPATVAAAAAGSGPKDPLARKMRLRRRKDSAQDDQAKQVLKGMSDVAQEKNRKQEESAEAGAPGGKVRRWDQGLEKPRLDYSEFFTEDVGQLPGLTIWQIENFVPVLVEEDLHGKFYEADCYIVLKTFLDDSGSLNWEIYYWIGGEATLDKKACSAIHAVNLRNYLGAECRTVREEMGDESEEFLQVFDNDISYIEGGTASGFYTVEDTHYVTRMYRVYGKKNIKLEPVPLKGASLDPRFVFLLDRGLDIYVWRGAQATLSSTTKARLFAEKINKNERKGKAEISLLVQGQEPPEFWETLGGEPSEIKKHVPDDFWPPQPKLYKVGLGLGYLELPQINYKLSVEHKKRPKVELMPRMRLLQSLLDTRCVYILDCWSDVFIWLGRKSPRLVRAAALKLGQELCGMLHRPRHAMVSRSLEGTEAQVFKAKFKNWDDVLSVDYTRNAEAMLQGPGLAGKVKRDAEKKDQMKADLTALFLPRQPPMALAEAEQLMEEWNEDLDGMEGFVLEGKKFARLPEEEFGHFYTQDCYVFLCRYWVPVEYEEEEKEEEKAGAEDKEGKEAAAEAEEKQPEEDFQCIVYFWQGREASNMGWLTFTFSLQKKFESLFPGKLEVVRMTQQQENPKFLSHFKRKFIIHRGKRKAAQGALQPSLYQIRTNGSALCTRCIQINTDSSLLNSEFCFILKVPFESEDNQGIVYAWVGRASDPDEAKLAEDILNSMFEASYSKQVINEGEEPENFFWVGIGAQKPYDDDAEYMKHTRLFRCSNEKGYFAVTEKCSDFCQDDLADDDIMLLDNGQEVYMWVGSQTSQVEIKLSLKACQVYIQHMRSKEHERPRRLRLVRKGNEQHAFTRCFHAWSTFRQALA", "length": 1213, "header": "tr|A0AAA9TC31-1|A0AAA9TV36_BOVIN Computationally mapped isoform of FLII actin remodeling protein OS=Bos taurus OX=9913 GN=FLII PE=4 SV=1 CANONICAL=A0AAA9TV36-1" }, "locus": { "chromosome": "19", "start_pos": 34398723, "end_pos": 34386891, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000105156.2", "url": "https://www.ensembl.org/id/ENSBTAT00000105156.2" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000094397.1", "url": "https://www.ensembl.org/id/ENSBTAP00000094397.1" } ] } }, { "isoform_ac": "A0AAA9TV36-1", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TV36/entry", "sequence": { "sequence": "DVPGLRPAPGGYFPENVKAMTSLRWLKLNRTGLCYLPEELASLQKLEHLSVSHNNLTTLHGELSSLPSLRAIVARANSLKNSGVPDDIFKLDDLSVLDLSYNQLTECPRELENAKNMLVLNLSHNSIDSIPNQLFINLTDLLYLDLSENRLESLPPQMRRLVHLQTLVLNGNPLLHAQLRQLPALTALQTLHLRNTQRTQSNLPTSLEGLSHLADVDLSCNDLTRVPECLYALPGLRRLNLSSNQIAELSLCIDQWVHLETLNLSRNQLTSLPSAICKLTKLKRLYLNSNQLDFDGLPSGIGKLSSLEEFMAANNKLELIPESLCRCTKLRKLVLNKNRLVTLPEAIHFLTEIEVLDVRENPSLVMPPKPVDRAAEWYNIDFSLQNQLRLAGASPATVAAAAAAGSGPKDPLARKMRLRRRKDSAQDDQAKQVLKGMSDVAQEKNRKQEESAEAGAPGGKVRRWDQGLEKPRLDYSEFFTEDVGQLPGLTIWQIENFVPVLVEEDLHGKFYEADCYIVLKTFLDDSGSLNWEIYYWIGGEATLDKKACSAIHAVNLRNYLGAECRTVREEMGDESEEFLQVFDNDISYIEGGTASGFYTVEDTHYVTRMYRVYGKKNIKLEPVPLKGASLDPRFVFLLDRGLDIYVWRGAQATLSSTTKARLFAEKINKNERKGKAEISLLVQGQEPPEFWETLGGEPSEIKKHVPDDFWPPQPKLYKVGLGLGYLELPQINYKLSVEHKKRPKVELMPRMRLLQSLLDTRCVYILDCWSDVFIWLGRKSPRLVRAAALKLGQELCGMLHRPRHAMVSRSLEGTEAQVFKAKFKNWDDVLSVDYTRNAEAMLQGPGLAGKVKRDAEKKDQMKADLTALFLPRQPPMALAEAEQLMEEWNEDLDGMEGFVLEGKKFARLPEEEFGHFYTQDCYVFLCRYWVPVEYEEEEKEEEKAGAEDKEGKEAAAEAEEKQPEEDFQCIVYFWQGREASNMGWLTFTFSLQKKFESLFPGKLEVVRMTQQQENPKFLSHFKRKFIIHRGKRKAAQGALQPSLYQIRTNGSALCTRCIQINTDSSLLNSEFCFILKVPFESEDNQGIVYAWVGRASDPDEAKLAEDILNSMFEASYSKQVINEGEEPENFFWVGIGAQKPYDDDAEYMKHTRLFRCSNEKGYFAVTEKCSDFCQDDLADDDIMLLDNGQEVYMWVGSQTSQVEIKLSLKACQVYIQHMRSKEHERPRRLRLVRKGNEQHAFTRCFHAWSTFRQALA", "length": 1256, "header": "tr|A0AAA9TV36-1|A0AAA9TV36_BOVIN Isoform 1 of FLII actin remodeling protein OS=Bos taurus OX=9913 GN=FLII PE=4 SV=1 CANONICAL=A0AAA9TV36-1" }, "locus": { "chromosome": "19", "start_pos": 34398723, "end_pos": 34387051, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000097348.2", "url": "https://www.ensembl.org/id/ENSBTAT00000097348.2" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000102219.1", "url": "https://www.ensembl.org/id/ENSBTAP00000102219.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [], "orthologs": [], "go_annotation": { "categories": [ { "name": "Molecular Function", "total": 1, "go_terms": [ { "name": "actin filament binding", "id": "GO:0051015", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0051015", "evidence": [ { "database": "UniProtKB", "id": "A0AAA9TV36", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TV36" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 5, "go_terms": [ { "name": "nucleus", "id": "GO:0005634", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005634", "evidence": [ { "database": "UniProtKB", "id": "A0AAA9TV36", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TV36" } ], "pmid": "" }, { "name": "centrosome", "id": "GO:0005813", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005813", "evidence": [ { "database": "UniProtKB", "id": "A0AAA9TV36", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TV36" } ], "pmid": "" }, { "name": "focal adhesion", "id": "GO:0005925", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005925", "evidence": [ { "database": "UniProtKB", "id": "A0AAA9TV36", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TV36" } ], "pmid": "" }, { "name": "brush border", "id": "GO:0005903", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005903", "evidence": [ { "database": "UniProtKB", "id": "A0AAA9TV36", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TV36" } ], "pmid": "" }, { "name": "podosome", "id": "GO:0002102", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0002102", "evidence": [ { "database": "UniProtKB", "id": "A0AAA9TV36", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TV36" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 2, "go_terms": [ { "name": "DNA-templated transcription", "id": "GO:0006351", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006351", "evidence": [ { "database": "UniProtKB", "id": "A0AAA9TV36", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TV36" } ], "pmid": "" }, { "name": "sarcomere organization", "id": "GO:0045214", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0045214", "evidence": [ { "database": "UniProtKB", "id": "A0AAA9TV36", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TV36" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 1049, "end_pos": 1051, "annotation": "n_glycosylation_sequon" }, { "start_pos": 121, "end_pos": 123, "annotation": "n_glycosylation_sequon" }, { "start_pos": 137, "end_pos": 139, "annotation": "n_glycosylation_sequon" }, { "start_pos": 240, "end_pos": 242, "annotation": "n_glycosylation_sequon" }, { "start_pos": 263, "end_pos": 265, "annotation": "n_glycosylation_sequon" }, { "start_pos": 29, "end_pos": 31, "annotation": "n_glycosylation_sequon" }, { "start_pos": 55, "end_pos": 57, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A0AAA9TV36", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TV36" }, { "id": "PF23598", "database": "Pfam", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF23598" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "Disease resistance R13L4/SHOC-2-like LRR", "eco_id": "ECO_0000259", "start_pos": 231, "end_pos": 336, "start_aa": "Tyr", "end_aa": "Asn", "glycosite_overlap": [] }, { "evidence": [ { "id": "A0AAA9TV36", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TV36" }, { "id": "PF00626", "database": "Pfam", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00626" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "Gelsolin-like", "eco_id": "ECO_0000259", "start_pos": 507, "end_pos": 579, "start_aa": "His", "end_aa": "Leu", "glycosite_overlap": [] } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 1049, "end_pos": 1051 }, { "start_pos": 121, "end_pos": 123 }, { "start_pos": 137, "end_pos": 139 }, { "start_pos": 240, "end_pos": 242 }, { "start_pos": 263, "end_pos": 265 }, { "start_pos": 29, "end_pos": 31 }, { "start_pos": 55, "end_pos": 57 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ], "tool_support": { "graph_view": "yes" } }, { "uniprot_canonical_ac": "A0AAA9TS75-1", "uniprot_ac": "A0AAA9TS75", "uniprot_id": "A0AAA9TS75_BOVIN", "mass": { "chemical_mass": 86991.0, "monoisotopic_mass": 86991.0 }, "refseq": {}, "gene_names": [ { "name": "CASS4", "type": "recommended", "evidence": [ { "id": "A0AAA9TS75", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TS75" } ] } ], "protein_names": [ { "name": "Cas scaffolding protein family member 4", "type": "recommended", "evidence": [ { "id": "A0AAA9TS75", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TS75/entry#names_and_taxonomy" } ] } ], "function": [ { "annotation": "Docking protein that plays a role in tyrosine kinase-based signaling related to cell adhesion and cell spreading. Regulates PTK2/FAK1 activity, focal adhesion integrity, and cell spreading.", "evidence": [ { "database": "UniProtKB", "id": "F1N289", "url": "https://www.uniprot.org/uniprotkb/F1N289#function" }, { "database": "UniProtKB", "id": "ARBA00055892", "url": "https://www.uniprot.org/uniprotkb/ARBA00055892#function" }, { "database": "UniProtKB", "id": "A0AAA9TS75", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TS75#function" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Bos taurus", "taxid": 9913, "evidence": [ { "database": "UniProtKB", "id": "A0AAA9TS75", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TS75" } ], "common_name": "Bovine", "glygen_name": "Bovine", "reference_species": "Bos taurus [9913]" } ], "gene": [ { "name": "CASS4", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TS75", "locus": { "chromosome": "13", "start_pos": 59499291, "end_pos": 59536797, "strand": "+", "evidence": [ { "database": "Ensembl Gene", "id": "ENSBTAG00000014555", "url": "https://www.ensembl.org/id/ENSBTAG00000014555" } ] } } ], "crossref": [ { "id": "A0AAA9TS75", "url": "https://alphafold.ebi.ac.uk/entry/A0AAA9TS75", "database": "AlphaFoldDB", "categories": [] }, { "id": "ENSBTAG00000014555", "url": "https://bgee.org/?page=gene&gene_id=ENSBTAG00000014555", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "cd12000", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd12000", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "512832", "url": "https://www.ncbi.nlm.nih.gov/gene/512832", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR001452", "url": "https://www.ebi.ac.uk/interpro/entry/IPR001452", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR014928", "url": "https://www.ebi.ac.uk/interpro/entry/IPR014928", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR021901", "url": "https://www.ebi.ac.uk/interpro/entry/IPR021901", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR035744", "url": "https://www.ebi.ac.uk/interpro/entry/IPR035744", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR036028", "url": "https://www.ebi.ac.uk/interpro/entry/IPR036028", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR037362", "url": "https://www.ebi.ac.uk/interpro/entry/IPR037362", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR038319", "url": "https://www.ebi.ac.uk/interpro/entry/IPR038319", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "TYERMDM", "url": "https://omabrowser.org/oma/group/TYERMDM/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "F1N289", "url": "https://www.orthodb.org/?gene=F1N289", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR10654", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR10654", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR10654:SF19", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR10654:SF19", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF08824", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF08824", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF12026", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF12026", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF14604", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF14604", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "A0AAA9TBS2", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TBS2", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0AAA9TBS2-1", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TBS2-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0AAA9TS75", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TS75", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0AAA9TS75-1", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TS75-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "F1N289", "url": "https://www.uniprot.org/uniprotkb/F1N289", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "F1N289-1", "url": "https://www.uniprot.org/uniprotkb/F1N289-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MKGAGILDGAPKTLLAKALYDNHPDSADELAFCRGDILTILEQNVPESEGWWKCLLHGRQGLAPANRLQILAEASTDRPRPPFLKGLDNAPAISQETYEVPTLLNPSSPVYEQMKSWVEGPPPPTVQVYEVPDPPACARIVCEKNLSFPKQAIFMIPRHARTSLPALGCQVYDVPAQSRCPPTLKEPGTQQLYDIPPSPQKAALGPPASQTNRQNIPPTSSIASRRGGCNTLPSPQKSEWIYDTPVSLEKADVRNASPSSSVEKSGHHVLPRCMSSFHSPPSSRAGTLSPHPQKNMPMQKKLSLPEIPSYSFPLAKAAFPLDEAVSYKVPSSFLIPRVEQQNTKPNIYDIPKARPRDPQAGKELGKANVPSENSLDHNSPWFPSQAESLSPEPDSSSVSSSDSRASILSSCSSTSTDSSSSSFSEESARELPLDLDLARETVTVLQHKVANSVGSLMLFVSRKWRFRDSLEANIDAIRRAADRTEESLKEFLDFARGVCGTTCNLTNSNLQARIRDQLQTISNSYQILLESKESLESCNWSLEVLVTDKIQNSPDDLERFVQVARMVPEDVKRFASIIIANGRLLFKPNCEKEDPVQLTPSAEFKLAKSIQLPQREIESYQRNTPFHKQKESKHSPELLEKNRTNVCEQNPSSLVPRPLSQQNPEKKTRLSEHCRLYFGALFKAISVLNSSLQNSQPPETFITQSKLVITVGQKLVDRLCRETQERDVRNEILRGSSCLCSLLKDLALATKHAVLQHPSPAALQHLRAEAKKLEQHAQQFRGTLE", "length": 785, "header": "tr|A0AAA9TS75-1|A0AAA9TS75_BOVIN Isoform 1 of Cas scaffolding protein family member 4 OS=Bos taurus OX=9913 GN=CASS4 PE=3 SV=1 CANONICAL=A0AAA9TS75-1" }, "isoforms": [ { "isoform_ac": "A0AAA9TBS2-1", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TBS2/entry", "sequence": { "sequence": "MKGAGILDGAPKTLLAKALYDNHPDSADELAFCRGDILTILEQNVPESEGWWKCLLHGRQGLAPANRLQILAEASTDRPRPPFLKGLDNAPAISQETYEVPTLLNPSSPVYEQMKSWVEGPPPPTVQVYEVPDPPACARIVCEKNLSFPKQAIFMIPRHARTSLPALGCQVYDVPAQSRCPPTLKEPGTQQLYDIPPSPQKAALGPPASQTNNPSSLVPRPLSQQNPEKKTRLSEHCRLYFGALFKAISVLNSSLQNSQPPETFITQSKLVITVGQKLVDRLCRETQERDVRNEILRGSSCLCSLLKDLALATKHAVLQHPSPAALQHLRAEAKKLEQHAQQFRGTLE", "length": 348, "header": "tr|A0AAA9TBS2-1|A0AAA9TS75_BOVIN Computationally mapped isoform of Cas scaffolding protein family member 4 OS=Bos taurus OX=9913 GN=CASS4 PE=3 SV=1 CANONICAL=A0AAA9TS75-1" }, "locus": { "chromosome": "13", "start_pos": 59534319, "end_pos": 59500295, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000124553.1", "url": "https://www.ensembl.org/id/ENSBTAT00000124553.1" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000095468.1", "url": "https://www.ensembl.org/id/ENSBTAP00000095468.1" } ] } }, { "isoform_ac": "A0AAA9TS75-1", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TS75/entry", "sequence": { "sequence": "MKGAGILDGAPKTLLAKALYDNHPDSADELAFCRGDILTILEQNVPESEGWWKCLLHGRQGLAPANRLQILAEASTDRPRPPFLKGLDNAPAISQETYEVPTLLNPSSPVYEQMKSWVEGPPPPTVQVYEVPDPPACARIVCEKNLSFPKQAIFMIPRHARTSLPALGCQVYDVPAQSRCPPTLKEPGTQQLYDIPPSPQKAALGPPASQTNRQNIPPTSSIASRRGGCNTLPSPQKSEWIYDTPVSLEKADVRNASPSSSVEKSGHHVLPRCMSSFHSPPSSRAGTLSPHPQKNMPMQKKLSLPEIPSYSFPLAKAAFPLDEAVSYKVPSSFLIPRVEQQNTKPNIYDIPKARPRDPQAGKELGKANVPSENSLDHNSPWFPSQAESLSPEPDSSSVSSSDSRASILSSCSSTSTDSSSSSFSEESARELPLDLDLARETVTVLQHKVANSVGSLMLFVSRKWRFRDSLEANIDAIRRAADRTEESLKEFLDFARGVCGTTCNLTNSNLQARIRDQLQTISNSYQILLESKESLESCNWSLEVLVTDKIQNSPDDLERFVQVARMVPEDVKRFASIIIANGRLLFKPNCEKEDPVQLTPSAEFKLAKSIQLPQREIESYQRNTPFHKQKESKHSPELLEKNRTNVCEQNPSSLVPRPLSQQNPEKKTRLSEHCRLYFGALFKAISVLNSSLQNSQPPETFITQSKLVITVGQKLVDRLCRETQERDVRNEILRGSSCLCSLLKDLALATKHAVLQHPSPAALQHLRAEAKKLEQHAQQFRGTLE", "length": 785, "header": "tr|A0AAA9TS75-1|A0AAA9TS75_BOVIN Isoform 1 of Cas scaffolding protein family member 4 OS=Bos taurus OX=9913 GN=CASS4 PE=3 SV=1 CANONICAL=A0AAA9TS75-1" }, "locus": { "chromosome": "13", "start_pos": 59534319, "end_pos": 59500295, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000090053.1", "url": "https://www.ensembl.org/id/ENSBTAT00000090053.1" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000099329.1", "url": "https://www.ensembl.org/id/ENSBTAP00000099329.1" } ] } }, { "isoform_ac": "F1N289-1", "url": "https://www.uniprot.org/uniprotkb/F1N289/entry", "sequence": { "sequence": "MKGAGILDGAPKTLLAKALYDNHPDSADELAFCRGDILTILEQNVPESEGWWKCLLHGRQGLAPANRLQILAEASTDRPRPPFLKGLDNAPAISQETYEVPTLLNPSSPVYEQMKSWVEGPPPPTVQVYEVPDPPACARIVCEKNLSFPKQAIFMIPRHARTSLPALGCQVYDVPAQSRCPPTLKEPGTQQLYDIPPSPQKAALGPPASQTNRQNIPPTSSIASRRGGCNTLPSPQKSEWIYDTPVSLEKADVRNASPSSSVEKSGHHVLPRCMSSFHSPPSSRAGTLSPHPQKNMPMQKKLSLPEIPSYSFPLAKAAFPLDEAVSYKVPSSFLIPRVEQQNTKPNIYDIPKARPRDPQAGKELGKANVPSENSLDHNSPWFPSQAESLSPEPDSSSVSSSDSRASILSSCSSTSTDSSSSSFSEESARELPLDLDLARETVTVLQHKVANSVGSLMLFVSRKWRFRDSLEANIDAIRRAADRTEESLKEFLDFARGVCGTTCNLTNSNLQARIRDQLQTISNSYQILLESKESLESCNWSLEVLVTDKIQNSPDDLERFVQVARMVPEDVKRFASIIIANGRLLFKPNCEKEDPVQLTPSAEFKLAKSIQLPQREIESYQRNTPFHKQKESKHSPELLEKNRTNVCEQKLPHLEEREKPILEQRSDENSDLETQNPSSLVPRPLSQQNPEKKTRLSEHCRLYFGALFKAISVLNSSLQNSQPPETFITQSKLVITVGQKLVDRLCRETQERDVRNEILRGSSCLCSLLKDLALATKHAVLQHPSPAALQHLRAEAKKLEQHAQQFRGTLE", "length": 811, "header": "tr|F1N289-1|F1N289_BOVIN Computationally mapped isoform of Cas scaffolding protein family member 4 OS=Bos taurus OX=9913 GN=CASS4 PE=3 SV=3 CANONICAL=A0AAA9TS75-1" }, "locus": { "chromosome": "13", "start_pos": 59534319, "end_pos": 59500295, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000019348.7", "url": "https://www.ensembl.org/id/ENSBTAT00000019348.7" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000019348.6", "url": "https://www.ensembl.org/id/ENSBTAP00000019348.6" } ] } } ], "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "other", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 125, "start_aa": "Thr", "end_pos": 125, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr125", "evidence": [ { "id": "", "database": "GlyGen", "url": "https://data.glygen.org/" } ], "filter_code": "000000000000000010000.00000000001000.0.01000" }, { "glytoucan_ac": "", "type": "O-linked", "subtype": "other", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 219, "start_aa": "Thr", "end_pos": 219, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr219", "evidence": [ { "id": "", "database": "GlyGen", "url": "https://data.glygen.org/" } ], "filter_code": "000000000000000010000.00000000001000.0.01000" } ], "phosphorylation": [], "glycation": [], "keywords": [ "glycoprotein", "glycoprotein_predicted" ], "publication": [], "pathway": [], "orthologs": [ { "uniprot_canonical_ac": "F1M0F6-1", "protein_name": "Cas scaffolding protein family member 4", "gene_name": "Cass4", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MRGTGIREGATKTLLARALYDNHPDCSDELAFSRGDILTIVEQNVPESEGWWKCLLHGRQGLAPANRLQVLRETPVDRPCPLPPRGLDSDLTGSEAPCQVFNSFSPPTPGPVYEPMKSWVEGPSPATAQVYELPDSPSSARIICEKTLNFPKQALFVLPRPTRASLPTLPSQVYDVPVQRQVSSTLERPEKQQFYDIPTSSQKAVFHISTSQASGPGVTLAPTTAFRQGGGYNPLSSPQKSDWIHDTPVSLGKADVRNASMTSFTKESCSNTIPGSSVVRIGAVTLSPQLGNAVQKKSSPPEETSYAFLTPRGDSLPSDAGSSYKVPSRFLIPRVERQNTKPNIYDTPKAMQGVFQNTSKATQGVSLAGKELERGREAPENSPWVSRQTNFLSPDSDRLSVASSDSRASVVSSCSSLSTDSSPGSSSEDSVKELWMDLDFAKETAVALQSRVASSVAGLLLFVSRTWRFKDSLETNVNRIRGAADRVEESLREFLDFAQGVGGLACNLTDSYLQARVRDQLQTISSSYQTLLDAKGTLDRCNWSLEVLVVDKAQSSVDDLERFVQVARVVPEDVKRFTSIVVANGKLLFKQNCERGEVDWRCERCIQPPQREAESHPERSSPFHKQPAAEHSLELAKKSRGDVCGQKSPNLQKKGKNTMEGKSNENQDFCGTSPTPLPSPSPSGQNVERKIRLSEHSRLYFGALFKAIGVFASSLSNSQPPEVFITQSKLAITIGQKLVDTLCSETQERDERNEILCGSSHLCGLLKDLALATKNAVIQYPSPSALGLLQSELEKLEYHSRKFRGTLE", "length": 808 }, "evidence": [ { "id": "A0AAA9TS75", "url": "https://omabrowser.org/oma/group/A0AAA9TS75/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "Q08EC4-1", "protein_name": "Cas scaffolding protein family member 4", "gene_name": "Cass4", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MRGTSIREGAPKTLLARALYDNHADCSDELAFSRGDILTIVEQNVPESEGWWRCLLHGRQGLAPANRLQVLRETPADRPCPLLPRGPDTDLTSSGAPYQVQDLISPPPQGPVYEPMRSWVEGPSPATAQVYELPESPSSARIICEKTLSFPKQALSVLPRPTRASLPTLPSQVYDVPVQRQGFSTLERLEKQQFYDIPTSSQKALLHSSTSQGRDVTLAPTMAFRQGGGYNPLSSPQKSERIHDTPVLLEKADVRNVSMTSFTKDSGSRAIPGSSAVHTGAVALSPQLGNTVQRKNSLPEEPTYAFPTSRDPLPSDAGGSYKVPSRFLIPRVEQQNTMPNIYDTPKAMQGVSHNAPKAMQGVSLAGKELERGREAPENSPWISGQTSFLSPDSDRLSVASSDSRASVVSSCSSISMDSSSGSSSEDSVKELWMDVDFAKETAVSLQHKVASSAAGLLLFVSRTWRFKDSLETNIHRIRRAADHVEESVREFLDFAQGVGGTACNLTDSYLQARIRDQLQTISSSYQTLLDAKGSLDRCNWSLEVLVTDKVQNSLDDLERFVATARIVPEDVKRFTSIVIANGKLLFKQNCEKGEMDLKCERCIRPPQRETESYQESSPFDRQPTTEHSFELARKNRVNVCWQQSPNLQEKGKPTMEGKSNRNPDFHGMSPPPLTSPSPSGQNTERKIHLSKHSRLYFGALFKAISVFASSLSNGQPPEVFITQSKLVITVGQKLVDTLCSETQEKDERNEILCGSSHLCGLLKDLALATKSAVIQYPSPSALSLLQSEVERLEHHSRKFRDTLE", "length": 804 }, "evidence": [ { "id": "A0AAA9TS75", "url": "https://omabrowser.org/oma/group/A0AAA9TS75/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q9NQ75-1", "protein_name": "Cas scaffolding protein family member 4", "gene_name": "CASS4", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MKGTGIMDCAPKALLARALYDNCPDCSDELAFSRGDILTILEQHVPESEGWWKCLLHGRQGLAPANRLQILTEVAADRPCPPFLRGLEEAPASSEETYQVPTLPRPPTPGPVYEQMRSWAEGPQPPTAQVYEFPDPPTSARIICEKTLSFPKQAILTLPRPVRASLPTLPSQVYDVPTQHRGPVVLKEPEKQQLYDIPASPKKAGLHPPDSQASGQGVPLISVTTLRRGGYSTLPNPQKSEWIYDTPVSPGKASVRNTPLTSFAEESRPHALPSSSSTFYNPPSGRSRSLTPQLNNNVPMQKKLSLPEIPSYGFLVPRGTFPLDEDVSYKVPSSFLIPRVEQQNTKPNIYDIPKATSSVSQAGKELEKAKEVSENSAGHNSSWFSRRTTSPSPEPDRLSGSSSDSRASIVSSCSTTSTDDSSSSSSEESAKELSLDLDVAKETVMALQHKVVSSVAGLMLFVSRKWRFRDYLEANIDAIHRSTDHIEESVREFLDFARGVHGTACNLTDSNLQNRIRDQMQTISNSYRILLETKESLDNRNWPLEVLVTDSVQNSPDDLERFVMVARMLPEDIKRFASIVIANGRLLFKRNCEKEETVQLTPNAEFKCEKYIQPPQRETESHQKSTPSTKQREDEHSSELLKKNRANICGQNPGPLIPQPSSQQTPERKPRLSEHCRLYFGALFKAISAFHGSLSSSQPAEIITQSKLVIMVGQKLVDTLCMETQERDVRNEILRGSSHLCSLLKDVALATKNAVLTYPSPAALGHLQAEAEKLEQHTRQFRGTLG", "length": 786 }, "evidence": [ { "id": "A0AAA9TS75", "url": "https://omabrowser.org/oma/group/A0AAA9TS75/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" } ], "go_annotation": { 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"total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ], "tool_support": { "graph_view": "yes" } }, { "uniprot_canonical_ac": "A0AAA9TT25-1", "uniprot_ac": "A0AAA9TT25", "uniprot_id": "A0AAA9TT25_BOVIN", "mass": { "chemical_mass": 55045.0, "monoisotopic_mass": 55045.0 }, "refseq": { "ac": "XP_002686331", "name": "box C/D snoRNA protein 1", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_002686331" }, "gene_names": [ { "name": "ZNHIT6", "type": "recommended", "evidence": [ { "id": "A0AAA9TT25", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TT25" } ] }, { "name": "ZNHIT6", "type": "synonym", "evidence": [ { "id": "XP_002686331", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_002686331" } ] } ], "protein_names": [ { "name": "Box C/D snoRNA protein 1", "type": "recommended", "evidence": [ { "id": "A0AAA9TT25", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TT25/entry#names_and_taxonomy" } ] }, { "name": "Zinc finger HIT domain-containing protein 6", "type": "synonym", "evidence": [ { "id": "A0AAA9TT25", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TT25/entry#names_and_taxonomy" } ] }, { "name": "box C/D snoRNA protein 1", "type": "synonym", "evidence": [ { "id": "XP_002686331", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_002686331" } ] } ], "function": [ { "annotation": "Required for box C/D snoRNAs accumulation involved in snoRNA processing, snoRNA transport to the nucleolus and ribosome biogenesis.", "evidence": [ { "database": "UniProtKB", "id": "A0A3Q1LV20", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1LV20#function" }, { "database": "UniProtKB", "id": "ARBA00049598", "url": "https://www.uniprot.org/uniprotkb/ARBA00049598#function" }, { "database": "UniProtKB", "id": "F1MYH0", "url": "https://www.uniprot.org/uniprotkb/F1MYH0#function" }, { "database": "UniProtKB", "id": "A0ABI0NX03", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NX03#function" }, { "database": "UniProtKB", "id": "A0AAA9RVV0", "url": "https://www.uniprot.org/uniprotkb/A0AAA9RVV0#function" }, { "database": "UniProtKB", "id": "A0AAA9TT25", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TT25#function" }, { "database": "UniProtKB", "id": "A0AAA9TZZ4", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TZZ4#function" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Bos taurus", "taxid": 9913, "evidence": [ { "database": "UniProtKB", "id": "A0AAA9TT25", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TT25" } ], "common_name": "Bovine", "glygen_name": "Bovine", "reference_species": "Bos taurus [9913]" } ], "gene": [ { "name": "ZNHIT6", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TT25", "locus": { "chromosome": "3", "start_pos": 58468715, "end_pos": 58374440, "strand": "-", "evidence": [ { "database": "Ensembl Gene", "id": "ENSBTAG00000021051", "url": "https://www.ensembl.org/id/ENSBTAG00000021051" } ] } } ], "crossref": [ { "id": "A0AAA9TT25", "url": "https://alphafold.ebi.ac.uk/entry/A0AAA9TT25", "database": "AlphaFoldDB", "categories": [] }, { "id": "ENSBTAG00000021051", "url": "https://bgee.org/?page=gene&gene_id=ENSBTAG00000021051", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "cd23023", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd23023", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "505578", "url": "https://www.ncbi.nlm.nih.gov/gene/505578", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR007529", "url": "https://www.ebi.ac.uk/interpro/entry/IPR007529", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR051639", "url": "https://www.ebi.ac.uk/interpro/entry/IPR051639", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR057721", "url": "https://www.ebi.ac.uk/interpro/entry/IPR057721", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "bta:505578", "url": "https://www.genome.jp/dbget-bin/www_bget?bta:505578", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "A0A3Q1LV20", "url": "https://www.orthodb.org/?gene=A0A3Q1LV20", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "F1MYH0", "url": "https://www.orthodb.org/?gene=F1MYH0", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR13483", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR13483", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR13483:SF3", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR13483:SF3", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF04438", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF04438", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF25790", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF25790", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "XP_002686331", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_002686331", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A3Q1LV20", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1LV20", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A3Q1LV20-1", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1LV20-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0AAA9RVV0", "url": "https://www.uniprot.org/uniprotkb/A0AAA9RVV0", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0AAA9RVV0-1", "url": "https://www.uniprot.org/uniprotkb/A0AAA9RVV0-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0AAA9TT25", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TT25", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0AAA9TT25-1", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TT25-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0AAA9TZZ4", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TZZ4", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0AAA9TZZ4-1", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TZZ4-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0ABI0NX03", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NX03", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0ABI0NX03-1", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NX03-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "F1MYH0", "url": "https://www.uniprot.org/uniprotkb/F1MYH0", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "F1MYH0-1", "url": "https://www.uniprot.org/uniprotkb/F1MYH0-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MDFAAESEEMSGGGLQSEAEGARLSLDTDQERVRTEESGDGEAENGLTGMEKTRAGEEESRRRAEEMRMDLTVVKQEVMDWSEMVEGTLNGQWVKQEEDRHEVKEEKPGTLEVKEEMDSSLMVKEEKVEETEIKEEKVKVKEEVMDWLEVKEEKKDILEIKREEVSLDQNIKKEEIMDEMYVKEEKYFPKEEMVDYTKVKEEPQINPSVGSKRKLAMSRCETCGTEEAKYRCPRCLRYSCSLPCVKKHKAELTCNGVRDKTAYVSIQQFTEMNLLSDYRFLEDVARTADHISRDAFLKRPISNKHMYFMKNRARKQGINLKLLPNGFTKRKENSTFFDKKKQQFCWHVKLQFPQSQAVYVEKRVPDDKTINEILRPYIDPEKSDPVIRQRLKAYICCQTGVQILMKVENMQQNLVRYYELDPDRSLLDNLRGKVILEYPTLHVVLKEYSNDMKVLHQVKSESTKNIGDEN", "length": 470, "header": "tr|A0AAA9TT25-1|A0AAA9TT25_BOVIN Isoform 1 of Box C/D snoRNA protein 1 OS=Bos taurus OX=9913 GN=ZNHIT6 PE=3 SV=2 CANONICAL=A0AAA9TT25-1" }, "isoforms": [ { "isoform_ac": "A0A3Q1LV20-1", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1LV20/entry", "sequence": { "sequence": "MDFAAESEEMSGGGLQSEAEGARLSLDTDQERVRTEESGDGEAENGLTGMEKTRAGEEESRRRAEEMRMDLTVVKQEVMDWSEMVEGTLNGQWVKQEEDRHEVKEEKPGTLEVKEEMDSSLMVKEEKVEETEIKEEKVKVKEEVMDWLEVKEEKKDILEIKREEVSLDQNIKKEEIMDEMYVKEEKYFPKEEMVDYTKVKEEPQINPSVGSKRKLAMSRCETCGTEEAKYRCPRCLRYSCSLPCVKKHKAELTCNGVRDKTAYVSIQQFTEMNLLSDYRFLEDVARTADHISRDAFLKRPISNKHMYFMKNRARKQGINLKLLPNGFTKRKENSTFFDKKKQQFCWHVKLQFPQSQAVYVEKRVPDDKTINEILRPYIDPEKSDPVIRQRLKAYICCQTGVQILMKVENMQQNLVRCVCMHPQSQLFYNSMNCSPSGSSVYGIS", "length": 444, "header": "tr|A0A3Q1LV20-1|A0AAA9TT25_BOVIN Computationally mapped isoform of Box C/D snoRNA protein 1 OS=Bos taurus OX=9913 GN=ZNHIT6 PE=3 SV=2 CANONICAL=A0AAA9TT25-1" }, "locus": { "chromosome": "3", "start_pos": 58415262, "end_pos": 58374589, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000077243.3", "url": "https://www.ensembl.org/id/ENSBTAT00000077243.3" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000059104.2", "url": "https://www.ensembl.org/id/ENSBTAP00000059104.2" } ] } }, { "isoform_ac": "A0AAA9RVV0-1", "url": "https://www.uniprot.org/uniprotkb/A0AAA9RVV0/entry", "sequence": { "sequence": "MDFAAESEEMSGGGLQSEAEGARLSLDTDQERVRTEESGDGEAENGLTGMEKTRAGEEESRRRAEEMRMDLTVVKEEMDSSLMVKEEKVEETEIKEEKVKVKEEVMDWLEVKEEKKDILEIKREEVSLDQNIKKEEIMDEMYVKEEKYFPKEEMVDYTKVKEEPQINPSVGSKRKLAMSRCETCGTEEAKYRCPRCLRYSCSLPCVKKHKAELTCNGVRDKTAYVSIQQFTEMNLLSDYRFLEDVARTADHISRDAFLKRPISNKHMYFMKNRARKQGINLKLLPNGFTKRKENSTFFDKKKQQFCWHVKLQFPQSQAVYVEKRVPDDKTINEILRPYIDPEKSDPVIRQRLKAYICCQTGVQILMKVENMQQNLVRYYELDPDRSLLDNLRGKVILEYPTLHVVLKEYSNDMKVLHQVKSESTKNIGDEN", "length": 431, "header": "tr|A0AAA9RVV0-1|A0AAA9TT25_BOVIN Computationally mapped isoform of Box C/D snoRNA protein 1 OS=Bos taurus OX=9913 GN=ZNHIT6 PE=3 SV=1 CANONICAL=A0AAA9TT25-1" }, "locus": { "chromosome": "3", "start_pos": 58435423, "end_pos": 58374589, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000100416.2", "url": "https://www.ensembl.org/id/ENSBTAT00000100416.2" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000075130.1", "url": "https://www.ensembl.org/id/ENSBTAP00000075130.1" } ] } }, { "isoform_ac": "A0AAA9TT25-1", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TT25/entry", "sequence": { "sequence": "MDFAAESEEMSGGGLQSEAEGARLSLDTDQERVRTEESGDGEAENGLTGMEKTRAGEEESRRRAEEMRMDLTVVKQEVMDWSEMVEGTLNGQWVKQEEDRHEVKEEKPGTLEVKEEMDSSLMVKEEKVEETEIKEEKVKVKEEVMDWLEVKEEKKDILEIKREEVSLDQNIKKEEIMDEMYVKEEKYFPKEEMVDYTKVKEEPQINPSVGSKRKLAMSRCETCGTEEAKYRCPRCLRYSCSLPCVKKHKAELTCNGVRDKTAYVSIQQFTEMNLLSDYRFLEDVARTADHISRDAFLKRPISNKHMYFMKNRARKQGINLKLLPNGFTKRKENSTFFDKKKQQFCWHVKLQFPQSQAVYVEKRVPDDKTINEILRPYIDPEKSDPVIRQRLKAYICCQTGVQILMKVENMQQNLVRYYELDPDRSLLDNLRGKVILEYPTLHVVLKEYSNDMKVLHQVKSESTKNIGDEN", "length": 470, "header": "tr|A0AAA9TT25-1|A0AAA9TT25_BOVIN Isoform 1 of Box C/D snoRNA protein 1 OS=Bos taurus OX=9913 GN=ZNHIT6 PE=3 SV=2 CANONICAL=A0AAA9TT25-1" }, "locus": { "chromosome": "3", "start_pos": 58435423, "end_pos": 58374589, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000101944.2", "url": "https://www.ensembl.org/id/ENSBTAT00000101944.2" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000101765.2", "url": "https://www.ensembl.org/id/ENSBTAP00000101765.2" } ] } }, { "isoform_ac": "A0AAA9TZZ4-1", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TZZ4/entry", "sequence": { "sequence": "MDFAAESEEMSGGGLQSEAEGARLSLDTDQERVRTEESGDGEAENGLTGMEKTRAGEEESRRRAEEMRMDLTVVKQEVMDWSEMVEGTLNGQWVKQEEDRHEVKEEKPGTLEVKEEMDSSLMVKEEKVEETEIKEEKVKVKEEVMDWLEVKEEKKDILEIKREEVSLDQNIKKEEIMDEMYVKEEKYFPKEEMVDYTKVKEEPQINPSVGSKRKLAMSRCETCGTEEAKYRCPRCLRYSCSLPCVKKHKAELTCNGVRDKTAYVSIQQFTEMNLLSDYRFLEDVARTADHISRDAFLKRPISNKHMYFMKNRARKQGINLKLLPNGFTKRKENSTFFDKKKQQFCWHVKLQFPQSQAVYVEKRVPDDKTINEILRPYIDPEKSDPVIRQRYYELDPDRSLLDNLRGKVILEYPTLHVVLKEYSNDMKVLHQVKSESTKNIGDEN", "length": 444, "header": "tr|A0AAA9TZZ4-1|A0AAA9TZZ4_BOVIN Computationally mapped isoform of Box C/D snoRNA protein 1 OS=Bos taurus OX=9913 GN=ZNHIT6 PE=3 SV=1 CANONICAL=A0AAA9TT25-1" }, "locus": { "chromosome": "3", "start_pos": 58435423, "end_pos": 58374589, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000112232.2", "url": "https://www.ensembl.org/id/ENSBTAT00000112232.2" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000102880.1", "url": "https://www.ensembl.org/id/ENSBTAP00000102880.1" } ] } }, { "isoform_ac": "A0ABI0NX03-1", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NX03/entry", "sequence": { "sequence": "MDFAAESEEMSGGGLQSEAEGARLSLDTDQERVRTEESGDGEAENGLTGMEKTRAGEEESRRRAEEMRMDLTVVKQEVMDWSEMVEGTLNGQWVKQEEDRHEVKEEKPGTLEVKEEMDSSLMVKEEKVEETEIKEEKVKVKEEVMDWLEVKEEKKDILEIKREEVSLDQNIKKEEIMDEMYVKEEKYFPKEEMVDYTKVKEEPQINPSVGSKRKLAMSRCETCGTEEAKYRCPRCLRYSCSLPCVKKHKAELTCNGVRDKTAYVSIQQFTEMNLLSDYRFLEDVARTADHISRDAFLKRPISNKHMYFMKNRARKQGINLKLLPNGFTKRKENSTFFDKKVPDDKTINEILRPYIDPEKSDPVIRQRLKAYICCQTGVQILMKVENMQQNLVRYYELDPDRSLLDNLRGKVILEYPTLHVVLKEYSNDMKVLHQVKSESTKNIGDEN", "length": 447, "header": "tr|A0ABI0NX03-1|A0ABI0NX03_BOVIN Computationally mapped isoform of Box C/D snoRNA protein 1 OS=Bos taurus OX=9913 GN=ZNHIT6 PE=3 SV=1 CANONICAL=A0AAA9TT25-1" }, "locus": { "chromosome": "3", "start_pos": 58435423, "end_pos": 58374589, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000142612.1", "url": "https://www.ensembl.org/id/ENSBTAT00000142612.1" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000104123.1", "url": "https://www.ensembl.org/id/ENSBTAP00000104123.1" } ] } }, { "isoform_ac": "F1MYH0-1", "url": "https://www.uniprot.org/uniprotkb/F1MYH0/entry", "sequence": { "sequence": "MDFAAESEEMSGGGLQSEAEGARLSLDTDQERVRTEESGDGEAENGLTGMEKTRAGEEESRRRAEEMRMDLTVVKQEVMDWSEMVEGTLNGQWVKQEEDRHEVKEEKPGTLEVKEEMDSSLMVKEEKVEETEIKEEKVKVKEEVMDWLEVKEEKKDILEIKREEVSLDQNIKKEEIMDEMYVKEEKYFPKEEMVDYTKVKEEPQINPSVGSKRKLAMSRCETCGTEEAKYRCPRCLRYSCSLPCVKKHKAELTCNGVRDKTAYVSIQQFTEMNLLSDYRFLEDVARTADHISRDAFLKRPISNKHMYFMKNRARKQGINLKLLPNGFTKRKENSTFFDKKKQQFCWHVKLQFPQSQAVYVEKRVPDDKTINEILRPYIDPEKSDPVIRQRLKAYICCQTGVQILMKVENMQQNLVRYYELDPDRSLLDNLRGKVILEYPTLHVVLKEYSNDMKVLHQGWISKQPEAVVWTGILIWKSPGILHPLK", "length": 485, "header": "tr|F1MYH0-1|F1MYH0_BOVIN Computationally mapped isoform of Box C/D snoRNA protein 1 OS=Bos taurus OX=9913 GN=ZNHIT6 PE=3 SV=4 CANONICAL=A0AAA9TT25-1" }, "locus": { "chromosome": "3", "start_pos": 58468613, "end_pos": 58374589, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000028038.8", "url": "https://www.ensembl.org/id/ENSBTAT00000028038.8" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000028038.7", "url": "https://www.ensembl.org/id/ENSBTAP00000028038.7" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [ { "id": "bta:505578", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?bta:505578", "resource": "KEGG Pathway" } ], "orthologs": [], "go_annotation": { "categories": [ { "name": "Molecular Function", "total": 4, "go_terms": [ { "name": "zinc ion binding", "id": "GO:0008270", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008270", "evidence": [ { "database": "UniProtKB", "id": "A0AAA9TT25", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TT25" } ], "pmid": "" }, { "name": "identical protein binding", "id": "GO:0042802", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0042802", "evidence": [ { "database": "UniProtKB", "id": "A0AAA9TT25", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TT25" } ], "pmid": "" }, { "name": "ATPase binding", "id": "GO:0051117", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0051117", "evidence": [ { "database": "UniProtKB", "id": "A0AAA9TT25", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TT25" } ], "pmid": "" }, { "name": "TFIID-class transcription factor complex binding", "id": "GO:0001094", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0001094", "evidence": [ { "database": "UniProtKB", "id": "A0AAA9TT25", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TT25" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 5, "go_terms": [ { "name": "ribosome biogenesis", "id": "GO:0042254", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0042254", "evidence": [ { "database": "UniProtKB", "id": "A0AAA9TT25", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TT25" } ], "pmid": "" }, { "name": "protein complex oligomerization", "id": "GO:0051259", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0051259", "evidence": [ { "database": "UniProtKB", "id": "A0AAA9TT25", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TT25" } ], "pmid": "" }, { "name": "box C/D snoRNP 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"end_aa": "Cys", "glycosite_overlap": [] } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 333, "end_pos": 335 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": 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and Pathway" ] }, { "id": "25098", "url": "https://www.rhea-db.org/rhea/25098", "database": "Rhea", "categories": [ "Enzyme and Pathway" ] }, { "id": "25237", "url": "https://www.rhea-db.org/rhea/25237", "database": "Rhea", "categories": [ "Enzyme and Pathway" ] }, { "id": "27686", "url": "https://www.rhea-db.org/rhea/27686", "database": "Rhea", "categories": [ "Enzyme and Pathway" ] }, { "id": "30347", "url": "https://www.rhea-db.org/rhea/30347", "database": "Rhea", "categories": [ "Enzyme and Pathway" ] }, { "id": "44640", "url": "https://www.rhea-db.org/rhea/44640", "database": "Rhea", "categories": [ "Enzyme and Pathway" ] }, { "id": "84315", "url": "https://www.rhea-db.org/rhea/84315", "database": "Rhea", "categories": [ "Enzyme and Pathway" ] }, { "id": "A0AAA9RYF2", "url": "https://www.uniprot.org/uniprotkb/A0AAA9RYF2", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0AAA9RYF2-1", "url": "https://www.uniprot.org/uniprotkb/A0AAA9RYF2-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0AAA9SAK2", "url": "https://www.uniprot.org/uniprotkb/A0AAA9SAK2", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0AAA9SAK2-1", "url": "https://www.uniprot.org/uniprotkb/A0AAA9SAK2-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0AAA9STE0", "url": "https://www.uniprot.org/uniprotkb/A0AAA9STE0", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0AAA9STE0-1", "url": "https://www.uniprot.org/uniprotkb/A0AAA9STE0-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0AAA9TUI5", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TUI5", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0AAA9TUI5-1", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TUI5-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0ABI0NYI8", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NYI8", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0ABI0NYI8-1", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NYI8-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "F1MCI2", "url": "https://www.uniprot.org/uniprotkb/F1MCI2", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "F1MCI2-1", "url": "https://www.uniprot.org/uniprotkb/F1MCI2-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MTSILRSPQALQLTLALIKPDAVAHPLILEAVHQQILSNKFLIVRMRELLWRKEDCQKFYREHEGRFFYQRLVEFMASSLLSALGSSTQLESGPIRAYILAHKDAIQLWRTVMGPTRVFRARHVAPDSIRGSFGLTDTRNTTHGSDSVVSASREIAAFFPDFSEQRWYEEEEPQLRCGPVHYSPEGGIHFAAPSGGLGPA", "length": 200, "header": "tr|A0AAA9TUI5-1|A0AAA9TUI5_BOVIN Isoform 1 of Nucleoside diphosphate kinase OS=Bos taurus OX=9913 GN=NME6 PE=3 SV=1 CANONICAL=A0AAA9TUI5-1" }, "isoforms": [ { "isoform_ac": "A0AAA9RYF2-1", "url": "https://www.uniprot.org/uniprotkb/A0AAA9RYF2/entry", "sequence": { "sequence": "MTSILRSPQALQLTLALIKPDAVAHPLILEAVHQQILSNKFLIVRMRELLWRKEDCQKFYREHEDSVVSASREIAAFFPDFSEQRWYEEEEPQLRCGPVHYSPEGGIHFAAPSGGLGPA", "length": 119, "header": "tr|A0AAA9RYF2-1|A0AAA9TUI5_BOVIN Computationally mapped isoform of Nucleoside diphosphate kinase OS=Bos taurus OX=9913 GN=NME6 PE=3 SV=1 CANONICAL=A0AAA9TUI5-1" }, "locus": { "chromosome": "22", "start_pos": 51564273, "end_pos": 51560512, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000134733.2", "url": "https://www.ensembl.org/id/ENSBTAT00000134733.2" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000076140.1", "url": "https://www.ensembl.org/id/ENSBTAP00000076140.1" } ] } }, { "isoform_ac": "A0AAA9SAK2-1", "url": "https://www.uniprot.org/uniprotkb/A0AAA9SAK2/entry", "sequence": { "sequence": "IAQNLDGPIRAYILAHKDAIQLWRTVMGPTRVFRARHVAPDSIRGSFGLTDTRNTTHGSDSVVSASREIAAFFPDFSEQRWYEEEEPQLRCGPVHYSPEGGIHFAAPSGGLGPA", "length": 114, "header": "tr|A0AAA9SAK2-1|A0AAA9TUI5_BOVIN Computationally mapped isoform of Nucleoside diphosphate kinase OS=Bos taurus OX=9913 GN=NME6 PE=3 SV=1 CANONICAL=A0AAA9TUI5-1" }, "locus": { "chromosome": "22", "start_pos": 51564273, "end_pos": 51558069, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000121952.1", "url": "https://www.ensembl.org/id/ENSBTAT00000121952.1" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000083116.1", "url": "https://www.ensembl.org/id/ENSBTAP00000083116.1" } ] } }, { "isoform_ac": "A0AAA9STE0-1", "url": "https://www.uniprot.org/uniprotkb/A0AAA9STE0/entry", "sequence": { "sequence": "IAQNLEREMTSILRSPQALQLTLALIKPDAVAHPLILEAVHQQILSNKFLIVRMRELLWRKEDCQKFYREHEGRFFYQRLVEFMASGPIRAYILAHKDAIQLWRTVMGPTRVFRARHVAPDSIRGSFGLTDTRNTTHGSDSVVSASREIAAFFPDFSEQRWYEEEEPQLRCGPVHYSPEGGIHFAAPSGGLGPA", "length": 194, "header": "tr|A0AAA9STE0-1|A0AAA9TUI5_BOVIN Computationally mapped isoform of Nucleoside diphosphate kinase OS=Bos taurus OX=9913 GN=NME6 PE=3 SV=1 CANONICAL=A0AAA9TUI5-1" }, "locus": { "chromosome": "22", "start_pos": 51564273, "end_pos": 51558069, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000132523.1", "url": "https://www.ensembl.org/id/ENSBTAT00000132523.1" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000089689.1", "url": "https://www.ensembl.org/id/ENSBTAP00000089689.1" } ] } }, { "isoform_ac": "A0AAA9TUI5-1", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TUI5/entry", "sequence": { "sequence": "MTSILRSPQALQLTLALIKPDAVAHPLILEAVHQQILSNKFLIVRMRELLWRKEDCQKFYREHEGRFFYQRLVEFMASSLLSALGSSTQLESGPIRAYILAHKDAIQLWRTVMGPTRVFRARHVAPDSIRGSFGLTDTRNTTHGSDSVVSASREIAAFFPDFSEQRWYEEEEPQLRCGPVHYSPEGGIHFAAPSGGLGPA", "length": 200, "header": "tr|A0AAA9TUI5-1|A0AAA9TUI5_BOVIN Isoform 1 of Nucleoside diphosphate kinase OS=Bos taurus OX=9913 GN=NME6 PE=3 SV=1 CANONICAL=A0AAA9TUI5-1" }, "locus": { "chromosome": "22", "start_pos": 51564273, "end_pos": 51560512, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000120386.2", "url": "https://www.ensembl.org/id/ENSBTAT00000120386.2" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000102281.1", "url": "https://www.ensembl.org/id/ENSBTAP00000102281.1" } ] } }, { "isoform_ac": "A0ABI0NYI8-1", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NYI8/entry", "sequence": { "sequence": "MTSILRSPQALQLTLALIKPDAVAHPLILEAVHQQILSNKFLIVRMRELLWRKEDCQKFYREHEGRFFYQRLVEFMASGPIRAYILAHKDAIQLWRTVMGPTRVFRARHVAPDSIRGSFGLTDTRNTTHGSDSVVSASREIAAFFPDFSEQRWYEEEEPQLRCGPVHYSPEGGIHFAAPSGGLGPA", "length": 186, "header": "tr|A0ABI0NYI8-1|A0ABI0NYI8_BOVIN Computationally mapped isoform of Nucleoside diphosphate kinase OS=Bos taurus OX=9913 GN=NME6 PE=3 SV=1 CANONICAL=A0AAA9TUI5-1" }, "locus": { "chromosome": "22", "start_pos": 51564273, "end_pos": 51560512, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000143935.1", "url": "https://www.ensembl.org/id/ENSBTAT00000143935.1" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000107340.1", "url": "https://www.ensembl.org/id/ENSBTAP00000107340.1" } ] } }, { "isoform_ac": "F1MCI2-1", "url": "https://www.uniprot.org/uniprotkb/F1MCI2/entry", "sequence": { "sequence": "MTSILRSPQALQLTLALIKPDAVAHPLILEILSNKFLIVRMRELLWRKEDCQKFYREHEGRFFYQRLVEFMASGPIRAYILAHKDAIQLWRTVMGPTRVFRARHVAPDSIRGSFGLTDTRNTTHGSDSVVSASREIAAFFPDFSEQRWYEEEEPQLRCGPVHYSPEGGIHFAAPSGGLGPA", "length": 181, "header": "tr|F1MCI2-1|F1MCI2_BOVIN Computationally mapped isoform of Nucleoside diphosphate kinase OS=Bos taurus OX=9913 GN=NME6 PE=3 SV=3 CANONICAL=A0AAA9TUI5-1" }, "locus": { "chromosome": "22", "start_pos": 51564273, "end_pos": 51560512, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000003935.7", "url": "https://www.ensembl.org/id/ENSBTAT00000003935.7" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000003935.6", "url": "https://www.ensembl.org/id/ENSBTAP00000003935.6" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [ "enzyme" ], "publication": [], "pathway": [ { "id": "bta:509354", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?bta:509354", "resource": "KEGG Pathway" }, { "id": "R-BTA-499943", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-BTA-499943", "resource": "Reactome", "description": "Interconversion of nucleotide di- and triphosphates" } ], "orthologs": [ { "uniprot_canonical_ac": "F1SKM8-1", "protein_name": "Nucleoside diphosphate kinase", "gene_name": "NME6", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MTSILRSPQALQLTLALIKPDAVAHPLILEAIHQQILSNKFLIVRMRELLWRKEDCQKFYQEHEGRFFYQRLVEFMASGPIRAYILAHKDAIQLWRTVMGPTRVFRARHIAPDSIRGSFGLTDTRNTTHGSDSVVSASREIAAFFPDFSEQRWYEEEEPQLRCGPVHYSPEGGIHCAAGTGGPGPA", "length": 186 }, "evidence": [ { "id": "A0AAA9TUI5", "url": "https://omabrowser.org/oma/group/A0AAA9TUI5/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "O75414-1", "protein_name": "Nucleoside diphosphate kinase 6, mitochondrial", "gene_name": "NME6", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MASILRSPQALQLTLALIKPDAVAHPLILEAVHQQILSNKFLIVRMRELLWRKEDCQRFYREHEGRFFYQRLVEFMASGPIRAYILAHKDAIQLWRTLMGPTRVFRARHVAPDSIRGSFGLTDTRNTTHGSDSVVSASREIAAFFPDFSEQRWYEEEEPQLRCGPVCYSPEGGVHYVAGTGGLGPA", "length": 186 }, "evidence": [ { "id": "A0AAA9TUI5", "url": "https://omabrowser.org/oma/group/A0AAA9TUI5/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "O88425-1", "protein_name": "Nucleoside diphosphate kinase 6, mitochondrial", "gene_name": "Nme6", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MTSILRSPQALQLTLALIKPDAVAHPLILEAVHQQILSNKFLIVRTRELQWKLEDCRRFYREHEGRFFYQRLVEFMTSGPIRAYILAHKDAIQLWRTLMGPTRVFRARYIAPDSIRGSLGLTDTRNTTHGSDSVVSASREIAAFFPDFSEQRWYEEEEPQLRCGPVHYSPEEGIHCAAETGGHKQPNKT", "length": 189 }, "evidence": [ { "id": "A0AAA9TUI5", "url": "https://omabrowser.org/oma/group/A0AAA9TUI5/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q54CG9-1", "protein_name": "Probable nucleoside diphosphate kinase DDB_G0292928", "gene_name": "", "tax_id": 44689, "organism": "Dictyostelium discoideum", "sequence": { "sequence": "MNKFKYTLAIIKPDILVKQNQNVDKIINKIESKFIIHQRKQIKLSLEEAEQFYKDHRGKFFYERLISFMTRGDIIPLILSDKSLEINNNNNNNNNNTSIKPWRDFIGPTHRDKAREQIGCLRGEYGTSDTRNAFHGSGSEEEAIDEINFFFPHFLENNKK", "length": 160 }, "evidence": [ { "id": "A0AAA9TUI5", "url": "https://omabrowser.org/oma/group/A0AAA9TUI5/", "database": "OMA" } ], "glygen_name": "Cellular slime mold", "common_name": "Social amoeba" }, { "uniprot_canonical_ac": "Q6DI51-1", "protein_name": "Nucleoside diphosphate kinase 6, mitochondrial", "gene_name": "nme6", "tax_id": 7955, "organism": "Danio rerio", "sequence": { "sequence": "MRCVKALQLTLAVIKPDAMAHPLILEALHQKILENFIIIRKKDLIWRKADSEMFYAEHSGRFFFQRLVEFMSSGPMRAYILAREDAITHWRTMMGPTKVFRARFSSPETLRGKYGLTDTRNTTHGSDSIESAKREISFFFPEFSAEEWMMREEPHFRLGHTEYNEESQIHTVKHT", "length": 175 }, "evidence": [ { "id": "A0AAA9TUI5", "url": "https://omabrowser.org/oma/group/A0AAA9TUI5/", "database": "OMA" } ], "glygen_name": "Zebrafish", "common_name": "Zebrafish" } ], "go_annotation": { "categories": [ { "name": "Molecular Function", "total": 3, "go_terms": [ { "name": "ATP binding", "id": "GO:0005524", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005524", "evidence": [ { "database": "UniProtKB", "id": "A0AAA9TUI5", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TUI5" } ], "pmid": "" }, { "name": "metal ion binding", "id": "GO:0046872", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0046872", "evidence": [ { "database": "UniProtKB", "id": "A0AAA9TUI5", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TUI5" } ], "pmid": "" }, { "name": "nucleoside diphosphate kinase activity", "id": "GO:0004550", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0004550", "evidence": [ { "database": "UniProtKB", "id": "A0AAA9TUI5", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TUI5" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 7, "go_terms": [ { "name": "nucleotide metabolic process", "id": "GO:0009117", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0009117", "evidence": [ { "database": "UniProtKB", "id": "A0AAA9TUI5", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TUI5" } ], "pmid": "" }, { "name": "GTP biosynthetic process", "id": "GO:0006183", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006183", "evidence": [ { "database": "UniProtKB", "id": "A0AAA9TUI5", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TUI5" } ], "pmid": "" }, { "name": "UTP biosynthetic process", "id": "GO:0006228", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006228", "evidence": [ { "database": "UniProtKB", "id": "A0AAA9TUI5", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TUI5" } ], "pmid": "" }, { "name": "CTP biosynthetic process", "id": "GO:0006241", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006241", "evidence": [ { "database": "UniProtKB", "id": "A0AAA9TUI5", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TUI5" } ], "pmid": "" }, { "name": "negative regulation of cell growth", "id": "GO:0030308", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030308", "evidence": [ { "database": "UniProtKB", "id": "A0AAA9TUI5", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TUI5" } ], "pmid": "" }, { "name": "negative regulation of mitotic nuclear division", "id": "GO:0045839", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0045839", "evidence": [ { "database": "UniProtKB", "id": "A0AAA9TUI5", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TUI5" } ], "pmid": "" }, { "name": "pyrimidine ribonucleotide salvage", "id": "GO:0010138", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0010138", "evidence": [ { "database": "UniProtKB", "id": "A0AAA9TUI5", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TUI5" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 3, "go_terms": [ { "name": "mitochondrial inner membrane", "id": "GO:0005743", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005743", "evidence": [ { "database": "UniProtKB", "id": "A0AAA9TUI5", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TUI5" } ], "pmid": "" }, { "name": "mitochondrial matrix", "id": "GO:0005759", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005759", "evidence": [ { "database": "UniProtKB", "id": "A0AAA9TUI5", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TUI5" } ], "pmid": "" }, { "name": "mitochondrion", "id": "GO:0005739", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005739", "evidence": [ { "database": "UniProtKB", "id": "A0AAA9TUI5", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TUI5" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 140, "end_pos": 142, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [ { "id": "18113", "name": "", "equation": "a ribonucleoside 5'-diphosphate + ATP = a ribonucleoside 5'-triphosphate + ADP", "summary": "", "cellular_location": "", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [ "A4IFD0-1", "Q3T0Q4-1", "A0AAF6ZEA8-1", "P00570-1", "Q2KIW9-1", "A0A3Q1LVZ0-1", "P52175-1", "Q0VCP1-1", "A0AAA9SPL6-1", "F1N2W6-1", "F1N6T4-1", "F1MUF5-1", "A0AAA9TUI5-1" ], "evidence": [ { "id": "18113", "database": "Rhea", "url": "https://www.rhea-db.org/rhea/18113" } ] }, { "id": "25098", "name": "", "equation": "UDP + ATP = UTP + ADP", "summary": "", "cellular_location": "", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [ "Q0VCP1-1", "A0A3Q1LVZ0-1", "A0AAF6ZEA8-1", "P00570-1", "Q2KIW9-1", "F1MUF5-1", "P52175-1", "Q3T0Q4-1", "A0AAA9TUI5-1", "F1N6T4-1" ], "evidence": [ { "id": "25098", "database": "Rhea", "url": "https://www.rhea-db.org/rhea/25098" } ] }, { "id": "25237", "name": "", "equation": "CDP + ATP = CTP + ADP", "summary": "", "cellular_location": "", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [ "Q0VCP1-1", "A0A3Q1LVZ0-1", "A0AAF6ZEA8-1", "F1MUF5-1", "P52175-1", "Q3T0Q4-1", "A0AAA9TUI5-1", "F1N6T4-1" ], "evidence": [ { "id": "25237", "database": "Rhea", "url": "https://www.rhea-db.org/rhea/25237" } ] }, { "id": "27686", "name": "", "equation": "GDP + ATP = GTP + ADP", "summary": "", "cellular_location": "", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [ "Q0VCP1-1", "A0A3Q1LVZ0-1", "A0AAF6ZEA8-1", "P00570-1", "Q2KIW9-1", "F1MUF5-1", "P52175-1", "Q3T0Q4-1", "A0AAA9TUI5-1", "F1N6T4-1" ], "evidence": [ { "id": "27686", "database": "Rhea", "url": "https://www.rhea-db.org/rhea/27686" } ] }, { "id": "30347", "name": "", "equation": "IDP + ATP = ITP + ADP", "summary": "", "cellular_location": "", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [ "P52175-1", "Q3T0Q4-1", "A0AAA9TUI5-1" ], "evidence": [ { "id": "30347", "database": "Rhea", "url": "https://www.rhea-db.org/rhea/30347" } ] }, { "id": "44640", "name": "", "equation": "a 2'-deoxyribonucleoside 5'-diphosphate + ATP = a 2'-deoxyribonucleoside 5'-triphosphate + ADP", "summary": "", "cellular_location": "", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [ "A0AAA9TUI5-1", "A4IFD0-1", "Q3T0Q4-1", "A0AAF6ZEA8-1", "P00570-1", "P52175-1", "Q2KIW9-1", "A0A3Q1LVZ0-1", "Q0VCP1-1", "A0AAA9SPL6-1", "F1N2W6-1", "F1N6T4-1" ], "evidence": [ { "id": "44640", "database": "Rhea", "url": "https://www.rhea-db.org/rhea/44640" } ] }, { "id": "84315", "name": "", "equation": "ADP + ATP = ADP + ATP", "summary": "", "cellular_location": "", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [ "P52175-1", "Q3T0Q4-1", "A0AAA9TUI5-1" ], "evidence": [ { "id": "84315", "database": "Rhea", "url": "https://www.rhea-db.org/rhea/84315" } ] }, { "id": "R-BTA-9605496", "name": "NME6 phosphorylates (d)NDPs to (d)NTPs", "equation": "", "summary": "This event has been computationally inferred from an event that has been demonstrated in another species.

The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.

More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "cellular_location": "mitochondrial matrix", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [ "A0AAA9TUI5-1" ], "evidence": [ { "id": "R-BTA-9605496", "database": "Reactome", "url": "https://www.reactome.org/PathwayBrowser/#R-BTA-9605496" } ] } ], "reaction_participants": [], "reaction_enzymes": [ { "uniprot_ac": "A0A3Q1LVZ0", "gene_name": "AK4", "activity": [ { "ec_number": "2.7.4.10", "activity": "a ribonucleoside 5'-triphosphate + AMP = a ribonucleoside 5'-diphosphate + ADP.", "evidence": [ { "id": "A0A3Q1LVZ0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1LVZ0" } ] }, { "ec_number": "2.7.4.6", "activity": "UDP + ATP = UTP + ADP.", "evidence": [ { "id": "A0A3Q1LVZ0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1LVZ0" } ] }, { "ec_number": "2.7.4.6", "activity": "", "evidence": [ { "id": "A0A3Q1LVZ0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1LVZ0" } ] }, { "ec_number": "2.7.4.10", "activity": "", "evidence": [ { "id": "A0A3Q1LVZ0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1LVZ0" } ] } ] }, { "uniprot_ac": "A0AAA9SPL6", "gene_name": "AK8", "activity": [ { "ec_number": "2.7.4.3", "activity": "AMP + ATP = 2 ADP.", "evidence": [ { "id": "A0AAA9SPL6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9SPL6" } ] }, { "ec_number": "2.7.4.6", "activity": "UDP + ATP = UTP + ADP.", "evidence": [ { "id": "A0AAA9SPL6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9SPL6" } ] }, { "ec_number": "2.7.4.3", "activity": "", "evidence": [ { "id": "A0AAA9SPL6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9SPL6" } ] }, { "ec_number": "2.7.4.6", "activity": "", "evidence": [ { "id": "A0AAA9SPL6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9SPL6" } ] } ] }, { "uniprot_ac": "A0AAA9TUI5", "gene_name": "NME6", "activity": [ { "ec_number": "2.7.4.6", "activity": "UDP + ATP = UTP + ADP.", "evidence": [ { "id": "A0AAA9TUI5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TUI5" } ] }, { "ec_number": "2.7.4.6", "activity": "", "evidence": [ { "id": "A0AAA9TUI5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TUI5" } ] } ] }, { "uniprot_ac": "A0AAF6ZEA8", "gene_name": "AK4", "activity": [ { "ec_number": "2.7.4.10", "activity": "a ribonucleoside 5'-triphosphate + AMP = a ribonucleoside 5'-diphosphate + ADP.", "evidence": [ { "id": "A0AAF6ZEA8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAF6ZEA8" } ] }, { "ec_number": "2.7.4.6", "activity": "UDP + ATP = UTP + ADP.", "evidence": [ { "id": "A0AAF6ZEA8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAF6ZEA8" } ] }, { "ec_number": "2.7.4.6", "activity": "", "evidence": [ { "id": "A0AAF6ZEA8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAF6ZEA8" } ] }, { "ec_number": "2.7.4.10", "activity": "", "evidence": [ { "id": "A0AAF6ZEA8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAF6ZEA8" } ] } ] }, { "uniprot_ac": "A4IFD0", "gene_name": "Ak5", "activity": [ { "ec_number": "2.7.4.3", "activity": "AMP + ATP = 2 ADP.", "evidence": [ { "id": "A4IFD0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A4IFD0" } ] }, { "ec_number": "2.7.4.6", "activity": "UDP + ATP = UTP + ADP.", "evidence": [ { "id": "A4IFD0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A4IFD0" } ] }, { "ec_number": "2.7.4.3", "activity": "", "evidence": [ { "id": "A4IFD0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A4IFD0" } ] }, { "ec_number": "2.7.4.6", "activity": "", "evidence": [ { "id": "A4IFD0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A4IFD0" } ] } ] }, { "uniprot_ac": "F1MUF5", "gene_name": "AK9", "activity": [ { "ec_number": "2.7.4.6", "activity": "UDP + ATP = UTP + ADP.", "evidence": [ { "id": "F1MUF5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MUF5" } ] }, { "ec_number": "2.7.4.4", "activity": "a ribonucleoside 5'-phosphate + ATP = a ribonucleoside 5'-diphosphate + ADP.", "evidence": [ { "id": "F1MUF5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MUF5" } ] }, { "ec_number": "2.7.4.6", "activity": "", "evidence": [ { "id": "F1MUF5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MUF5" } ] }, { "ec_number": "2.7.4.4", "activity": "", "evidence": [ { "id": "F1MUF5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MUF5" } ] } ] }, { "uniprot_ac": "F1N2W6", "gene_name": "CMPK2", "activity": [ { "ec_number": "2.7.4.14", "activity": "UMP + ATP = UDP + ADP.", "evidence": [ { "id": "F1N2W6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1N2W6" } ] }, 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"Protein Classification" ] }, { "id": "IPR051740", "url": "https://www.ebi.ac.uk/interpro/entry/IPR051740", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "DIESCHD", "url": "https://omabrowser.org/oma/group/DIESCHD/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "F1MH34", "url": "https://www.orthodb.org/?gene=F1MH34", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR46054", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR46054", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR46054:SF2", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR46054:SF2", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00035", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00035", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF16482", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF16482", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "XP_024857082", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_024857082", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0AAA9S8L6", "url": "https://www.uniprot.org/uniprotkb/A0AAA9S8L6", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0AAA9S8L6-1", "url": "https://www.uniprot.org/uniprotkb/A0AAA9S8L6-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0AAA9TSK7", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TSK7", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0AAA9TSK7-1", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TSK7-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "F1MH34", "url": "https://www.uniprot.org/uniprotkb/F1MH34", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "F1MH34-1", "url": "https://www.uniprot.org/uniprotkb/F1MH34-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MKLGKKPMYKPVDPYSRMQSTYNYNMRGGAYPPRYFYPFPVPPLLYQVELSVGGQQFNGKGKTRQAAKHDAAAKALRILQSEPPSERLEVNGRESEEENLNKSEISQVFEIALKRNLPVNFESFPPTQVARESGPPHMKSFVTRVSVGEFVGEGEGKSKKISKKNAAIAVLEELKKLPPLPTVERVKPRIKKKTKSIVRLQGGPECGQGMNPISRLAQIQQAKKEKEPEYLLLAERGLPRRREFVMQVKVGNHTAEGSGTNKKVAKRNAAENMLEILGFKVPQAQPSKPALKSEEKTPIKKPGDGRKVTFFEPGSGDENGTSNKEDEFRMPYLSHQQLPAGILPMVPEVAQAVGVSQGHHTKDFARVAPNPAKATVTAMIARELLYGGTSPTAETILKSNISSGHAPHGPLTRPSEQLDYLCTVQGFQVEYKDFPKNNKNEFVSLINCSSQPPLISHGIGKDVESCHDMAALNILKLLSELDQQNTEMPRTGNGPMSVCGRC", "length": 502, "header": "tr|A0AAA9TSK7-1|A0AAA9TSK7_BOVIN Isoform 1 of Double-stranded RNA-binding protein Staufen homolog 1 OS=Bos taurus OX=9913 GN=STAU1 PE=4 SV=1 CANONICAL=A0AAA9TSK7-1" }, "isoforms": [ { "isoform_ac": "A0AAA9S8L6-1", "url": "https://www.uniprot.org/uniprotkb/A0AAA9S8L6/entry", "sequence": { "sequence": "MSQVQVQVQNPSAALSGSQILNKNQSLLSQPLMSIPSTASSLPSENAGRPIQNSALPSASLTSTSAAAVPSNMAHPKEKTPMCLVNELARFNKIQPEYKLLREQGPAHCKVFTVQLTLGDQHWEAEGTSIKKAQHTAAAKALEGAKFPKPIVRPFRSEGRNPESITPTVELNALCMKLGKKPMYKPVDPYSRMQSTYNYNMRGGAYPPRYFYPFPVPPLLYQVELSVGGQQFNGKGKTRQAAKHDAAAKALRILQSEPPSERLEVNGRESEEENLNKSEISQVFEIALKRNLPVNFEVARESGPPHMKSFVTRVSVGEFVGEGEGKSKKISKKNAAIAVLEELKKLPPLPTVERVKPRIKKKTKSIVRLQGGPECGQGMNPISRLAQIQQAKKEKEPEYLLLAERGLPRRREFVMQVKVGNHTAEGSGTNKKVAKRNAAENMLEILGFKVPQAQPSKPALKSEEKTPIKKPGDGRKVTFFEPGSGDENGTSNKEDEFRMPYLSHQQLPAGILPMVPEVAQAVGVSQGHHTKDFARVAPNPAKATVTAMIARELLYGGTSPTAETILKSNISSGHAPHGPLTRPSEQLDYLCTVQGFQVEYKDFPKNNKNEFVSLINCSSQPPLISHGIGKDVESCHDMAALNILKLLSELDQQNTEMPRTGNGPMSVCGRC", "length": 671, "header": "tr|A0AAA9S8L6-1|A0AAA9TSK7_BOVIN Computationally mapped isoform of Double-stranded RNA-binding protein Staufen homolog 1 OS=Bos taurus OX=9913 GN=STAU1 PE=4 SV=1 CANONICAL=A0AAA9TSK7-1" }, "locus": { "chromosome": "13", "start_pos": 77278837, "end_pos": 77237409, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000131231.1", "url": "https://www.ensembl.org/id/ENSBTAT00000131231.1" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000079694.1", "url": "https://www.ensembl.org/id/ENSBTAP00000079694.1" } ] } }, { "isoform_ac": "A0AAA9TSK7-1", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TSK7/entry", "sequence": { "sequence": "MKLGKKPMYKPVDPYSRMQSTYNYNMRGGAYPPRYFYPFPVPPLLYQVELSVGGQQFNGKGKTRQAAKHDAAAKALRILQSEPPSERLEVNGRESEEENLNKSEISQVFEIALKRNLPVNFESFPPTQVARESGPPHMKSFVTRVSVGEFVGEGEGKSKKISKKNAAIAVLEELKKLPPLPTVERVKPRIKKKTKSIVRLQGGPECGQGMNPISRLAQIQQAKKEKEPEYLLLAERGLPRRREFVMQVKVGNHTAEGSGTNKKVAKRNAAENMLEILGFKVPQAQPSKPALKSEEKTPIKKPGDGRKVTFFEPGSGDENGTSNKEDEFRMPYLSHQQLPAGILPMVPEVAQAVGVSQGHHTKDFARVAPNPAKATVTAMIARELLYGGTSPTAETILKSNISSGHAPHGPLTRPSEQLDYLCTVQGFQVEYKDFPKNNKNEFVSLINCSSQPPLISHGIGKDVESCHDMAALNILKLLSELDQQNTEMPRTGNGPMSVCGRC", "length": 502, "header": "tr|A0AAA9TSK7-1|A0AAA9TSK7_BOVIN Isoform 1 of Double-stranded RNA-binding protein Staufen homolog 1 OS=Bos taurus OX=9913 GN=STAU1 PE=4 SV=1 CANONICAL=A0AAA9TSK7-1" }, "locus": { "chromosome": "13", "start_pos": 77271157, "end_pos": 77237409, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000125231.1", "url": "https://www.ensembl.org/id/ENSBTAT00000125231.1" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000101588.1", "url": "https://www.ensembl.org/id/ENSBTAP00000101588.1" } ] } }, { "isoform_ac": "F1MH34-1", "url": "https://www.uniprot.org/uniprotkb/F1MH34/entry", "sequence": { "sequence": "MSQVQVQVQNPSAALSGSQILNKNQSLLSQPLMSIPSTASSLPSENAGRPIQNSALPSASLTSTSAAAESITPTVELNALCMKLGKKPMYKPVDPYSRMQSTYNYNMRGGAYPPRYFYPFPVPPLLYQVELSVGGQQFNGKGKTRQAAKHDAAAKALRILQSEPPSERLEVNGRESEEENLNKSEISQVFEIALKRNLPVNFEVARESGPPHMKSFVTRVSVGEFVGEGEGKSKKISKKNAAIAVLEELKKLPPLPTVERVKPRIKKKTKSIVRLQGGPECGQGMNPISRLAQIQQAKKEKEPEYLLLAERGLPRRREFVMQVKVGNHTAEGSGTNKKVAKRNAAENMLEILGFKVPQAQPSKPALKSEEKTPIKKPGDGRKVTFFEPGSGDENGTSNKEDEFRMPYLSHQQLPAGILPMVPEVAQAVGVSQGHHTKDFARVAPNPAKATVTAMIARELLYGGTSPTAETILKSNISSGHAPHGPLTRPSEQLDYLCTVQGFQVEYKDFPKNNKNEFVSLINCSSQPPLISHGIGKDVESCHDMAALNILKLLSELDQQNTEMPRTGNGPMSVCGRC", "length": 577, "header": "tr|F1MH34-1|F1MH34_BOVIN Computationally mapped isoform of Double-stranded RNA-binding protein Staufen homolog 1 OS=Bos taurus OX=9913 GN=STAU1 PE=4 SV=3 CANONICAL=A0AAA9TSK7-1" }, "locus": { "chromosome": "13", "start_pos": 77278837, "end_pos": 77237409, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000000301.7", "url": "https://www.ensembl.org/id/ENSBTAT00000000301.7" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000000301.6", "url": "https://www.ensembl.org/id/ENSBTAP00000000301.6" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [], "orthologs": [ { "uniprot_canonical_ac": "A0A8C2M1P2-1", "protein_name": "Double-stranded RNA-binding protein Staufen homolog 1", "gene_name": "Stau1", "tax_id": 10029, "organism": "Cricetulus griseus", "sequence": { "sequence": "MYKPVDPHSRMQSTYSYGMRGGAYPPRYFYPFPVPPLLYQVELSVGGQQFNGKGKMRQTVKHDATARALRTLQNEPPPERLEMNGRELEEENLNKSEISQVFEIALKRNLPVNFESFPLTQVARESGPPHMKNFVTRVSVGEFVGEGEGKSKKISKKNAARAVLEQLRRLPPLPAVERVKPRIKKKSQPTCKLQTAPDYGQGMNPISRLAQIQQAKKDKEPEYTLLTERGLPRRREFVMQVKVGNHTAEGAGTNKKVAKRNAAENMLEILGFKVPQAQPAKPALKSEEKTPVKKPGDGRKVTFFEPSPGDENATSHKEDEFRMPYLSHQQLPAGILPMVPEVAQAVGVSQGHHTKDFTRAAPNPAKATVTAMIARELLYGGTSPTAETILKSNISSGHVPHGPRTRPSEQLYYLSRAQGFQVEYKDFPKNNKNECVSLINCSSQPPLVSHGIGKDVESCHDMAALNILKLLSELDQQSTEMPRTGNGPVSACGRC", "length": 495 }, "evidence": [ { "id": "A0AAA9TSK7", "url": "https://omabrowser.org/oma/group/A0AAA9TSK7/", "database": "OMA" } ], "glygen_name": "Hamster", "common_name": "Chinese hamster" }, { "uniprot_canonical_ac": "A0AC58JQK6-1", "protein_name": "Double-stranded RNA-binding protein Staufen homolog 1", "gene_name": "stau1", "tax_id": 7955, "organism": "Danio rerio", "sequence": { "sequence": "MSQLQFQAPGNPAPSSAPLQLAPPQPGFSIPCGTAPLPSESASHPLRNSALPSASATPFCNPTVSNMANPKEKTPMCLVNELARYNKIQPEYKLLSEEGPAHSKIFSVRLTLGDQHWDAEGTSIKKAQHSAASSALAQTTLPKPSHRSPRHPGKSPGGIYKGSEYNVTHTVELNALCMKLGKKPIYKPIDAYQGMRPAFNYNIRAPSPYARSMQHYYYPFPPVGPVLYHMELSIGGQQFHGKGRTRQAAKHDAAAKAIKYLQKEPILQQITEMTDEPAQENLNKSEISQVFEIALKRNMPVDFEVLKEAGAPHMKSFVVRVVVGEFAGEGEGKSKKIAKKQAAIAVLEELRRLPQLPATDKIPLRIKKKSKSIIKLQTSPEYGQGMNPISRLAQIQQAKKEKEPEYTLVTERGLPRRREFVMQVSVAGQNAEGMGPSKKVAKRNAAEKMLELLGFKVPQPQPPKPALKTDEKPPAKKLGDGRKVTFFEPGSMEKAGLVVSKEEDFRLPFLSHQQLPAGILPMVPEVAQAVGANQGPHAKDYGRTAAPNPANATVTAMIANELLYAGTSPTAEGILKTNNSLAHRPQGPLTRPSEQLSYLANVQGLQVEYKDFPKNNKNEFVSLINCSSQPPLISHGIGKDVESCHDMAALNILKLLSELDQQSNERTANGPMSGSVSCLQVFYVLIILQYKLVVLGLSRYWNSGPIVISVEHVNTMANQRCLRKYSVALKC", "length": 731 }, "evidence": [ { "id": "A0AAA9TSK7", "url": "https://omabrowser.org/oma/group/A0AAA9TSK7/", "database": "OMA" } ], "glygen_name": "Zebrafish", "common_name": "Zebrafish" }, { "uniprot_canonical_ac": "O95793-1", "protein_name": "Double-stranded RNA-binding protein Staufen homolog 1", "gene_name": "STAU1", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MSQVQVQVQNPSAALSGSQILNKNQSLLSQPLMSIPSTTSSLPSENAGRPIQNSALPSASITSTSAAAESITPTVELNALCMKLGKKPMYKPVDPYSRMQSTYNYNMRGGAYPPRYFYPFPVPPLLYQVELSVGGQQFNGKGKTRQAAKHDAAAKALRILQNEPLPERLEVNGRESEEENLNKSEISQVFEIALKRNLPVNFEVARESGPPHMKNFVTKVSVGEFVGEGEGKSKKISKKNAAIAVLEELKKLPPLPAVERVKPRIKKKTKPIVKPQTSPEYGQGINPISRLAQIQQAKKEKEPEYTLLTERGLPRRREFVMQVKVGNHTAEGTGTNKKVAKRNAAENMLEILGFKVPQAQPTKPALKSEEKTPIKKPGDGRKVTFFEPGSGDENGTSNKEDEFRMPYLSHQQLPAGILPMVPEVAQAVGVSQGHHTKDFTRAAPNPAKATVTAMIARELLYGGTSPTAETILKNNISSGHVPHGPLTRPSEQLDYLSRVQGFQVEYKDFPKNNKNEFVSLINCSSQPPLISHGIGKDVESCHDMAALNILKLLSELDQQSTEMPRTGNGPMSVCGRC", "length": 577 }, "evidence": [ { "id": "A0AAA9TSK7", "url": "https://omabrowser.org/oma/group/A0AAA9TSK7/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "Q9Z108-1", "protein_name": "Double-stranded RNA-binding protein Staufen homolog 1", "gene_name": "Stau1", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MYKPVDPHSRMQSTYSYGMRGGAYPPRYFYPFPVPPLLYQVELSVGGQQFNGKGKMRPPVKHDAPARALRTLQSEPLPERLEVNGREAEEENLNKSEISQVFEIALKRNLPVNFEVARESGPPHMKNFVTRVSVGEFVGEGEGKSKKISKKNAARAVLEQLRRLPPLPAVERVKPRIKKKSQPTCKTAPDYGQGMNPISRLAQIQQAKKEKEPEYMLLTERGLPRRREFVMQVKVGHHTAEGVGTNKKVAKRNAAENMLEILGFKVPQAQPAKPALKSEEKTPVKKPGDGRKVTFFEPSPGDENGTSNKDEEFRMPYLSHQQLPAGILPMVPEVAQAVGVSQGHHTKDFTRAAPNPAKATVTAMIARELLYGGTSPTAETILKSNISSGHVPHGPRTRPSEQLYYLSRAQGFQVEYKDFPKNNKNECVSLINCSSQPPLVSHGIGKDVESCHDMAALNILKLLSELDQQSTEMPRTGNGPVSACGRC", "length": 487 }, "evidence": [ { "id": "A0AAA9TSK7", "url": "https://omabrowser.org/oma/group/A0AAA9TSK7/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" } ], "go_annotation": { "categories": [ { "name": "Biological Process", "total": 6, "go_terms": [ { "name": "positive regulation by virus of viral protein levels in host cell", "id": "GO:0046726", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0046726", "evidence": [ { "database": "UniProtKB", "id": "A0AAA9TSK7", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TSK7" } ], "pmid": "" }, { "name": "positive regulation of viral genome replication", "id": "GO:0045070", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0045070", "evidence": [ { "database": "UniProtKB", "id": "A0AAA9TSK7", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TSK7" } ], "pmid": "" }, { "name": "germ cell development", "id": "GO:0007281", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007281", "evidence": [ { "database": "UniProtKB", "id": "A0AAA9TSK7", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TSK7" } ], "pmid": "" }, { "name": "protein localization to synapse", "id": "GO:0035418", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0035418", "evidence": [ { "database": "UniProtKB", "id": "A0AAA9TSK7", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TSK7" } ], "pmid": "" }, { "name": "intracellular mRNA localization", "id": "GO:0008298", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008298", "evidence": [ { "database": "UniProtKB", "id": "A0AAA9TSK7", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TSK7" } ], "pmid": "" }, { "name": "anterograde dendritic transport of messenger ribonucleoprotein complex", "id": "GO:0098964", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0098964", "evidence": [ { "database": "UniProtKB", "id": "A0AAA9TSK7", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TSK7" } ], "pmid": "" } ] }, { "name": "Molecular Function", "total": 3, "go_terms": [ { "name": "RNA binding", "id": "GO:0003723", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003723", "evidence": [ { "database": "UniProtKB", "id": "A0AAA9TSK7", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TSK7" } ], "pmid": "" }, { "name": "mRNA binding", "id": "GO:0003729", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003729", "evidence": [ { "database": "UniProtKB", "id": "A0AAA9TSK7", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TSK7" } ], "pmid": "" }, { "name": "double-stranded RNA binding", "id": "GO:0003725", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003725", "evidence": [ { "database": "UniProtKB", "id": "A0AAA9TSK7", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TSK7" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 11, "go_terms": [ { "name": "rough endoplasmic reticulum", "id": "GO:0005791", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005791", "evidence": [ { "database": "UniProtKB", "id": "A0AAA9TSK7", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TSK7" } ], "pmid": "" }, { "name": "cytosol", "id": "GO:0005829", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005829", "evidence": [ { "database": "UniProtKB", "id": "A0AAA9TSK7", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TSK7" } ], "pmid": "" }, { "name": "plasma membrane", "id": "GO:0005886", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005886", "evidence": [ { "database": "UniProtKB", "id": "A0AAA9TSK7", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TSK7" } ], "pmid": "" }, { "name": "dendrite", "id": "GO:0030425", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030425", "evidence": [ { "database": "UniProtKB", "id": "A0AAA9TSK7", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TSK7" } ], "pmid": "" }, { "name": "cell body", "id": "GO:0044297", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0044297", "evidence": [ { "database": "UniProtKB", "id": "A0AAA9TSK7", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TSK7" } ], "pmid": "" }, { "name": "cytoplasmic ribonucleoprotein granule", "id": "GO:0036464", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0036464", "evidence": [ { "database": "UniProtKB", "id": "A0AAA9TSK7", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TSK7" } ], "pmid": "" }, { "name": "protein-containing complex", "id": "GO:0032991", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0032991", "evidence": [ { "database": "UniProtKB", "id": "A0AAA9TSK7", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TSK7" } ], "pmid": "" }, { "name": "neuron projection", "id": "GO:0043005", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0043005", "evidence": [ { "database": "UniProtKB", "id": "A0AAA9TSK7", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TSK7" } ], "pmid": "" }, { "name": "neuronal cell body", "id": "GO:0043025", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0043025", "evidence": [ { "database": "UniProtKB", "id": "A0AAA9TSK7", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TSK7" } ], "pmid": "" }, { "name": "dendrite cytoplasm", "id": "GO:0032839", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0032839", "evidence": [ { "database": "UniProtKB", "id": "A0AAA9TSK7", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TSK7" } ], "pmid": "" }, { "name": "cytoplasmic stress granule", "id": "GO:0010494", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0010494", "evidence": [ { "database": "UniProtKB", "id": "A0AAA9TSK7", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TSK7" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 101, "end_pos": 103, "annotation": "n_glycosylation_sequon" }, { "start_pos": 252, "end_pos": 254, "annotation": "n_glycosylation_sequon" }, { "start_pos": 319, "end_pos": 321, "annotation": "n_glycosylation_sequon" }, { "start_pos": 400, "end_pos": 402, "annotation": "n_glycosylation_sequon" }, { "start_pos": 447, "end_pos": 449, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A0AAA9TSK7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TSK7" }, { "id": "PS50137", "database": "PROSITE", "url": "https://prosite.expasy.org/PS50137" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "DRBM", "eco_id": "ECO_0000259", "start_pos": 46, "end_pos": 81, "start_aa": "Tyr", "end_aa": "Ser", "glycosite_overlap": [] } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" }, { "name": "homologset.oma", "label": "OMA Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 101, "end_pos": 103 }, { "start_pos": 252, "end_pos": 254 }, { "start_pos": 319, "end_pos": 321 }, { "start_pos": 400, "end_pos": 402 }, { "start_pos": 447, "end_pos": 449 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { 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"database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001346854" } ] } ], "function": [ { "annotation": "Regulatory role in intramuscular fat deposition", "evidence": [ { "database": "RefSeq", "id": "NP_001346854", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001346854" }, { "database": "PubMed", "id": "24778332", "url": "https://glygen.org/publication/PubMed/24778332" } ] }, { "annotation": "Results show that chicken ovalbumin upstream promoter transcription factor II (COUP-TFII), hepatocyte nuclear factor 4alpha (HNF-4alpha) and HNF-4gamma regulate growth hormone receptor 1A promoter activity through binding to a common DNA element.", "evidence": [ { "database": "RefSeq", "id": "NP_001346854", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001346854" }, { "database": "PubMed", "id": "15171724", "url": "https://glygen.org/publication/PubMed/15171724" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": 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Classification" ] }, { "id": "cd06960", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd06960", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "404168", "url": "https://www.ncbi.nlm.nih.gov/gene/404168", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR000003", "url": "https://www.ebi.ac.uk/interpro/entry/IPR000003", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR000536", "url": "https://www.ebi.ac.uk/interpro/entry/IPR000536", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR001628", "url": "https://www.ebi.ac.uk/interpro/entry/IPR001628", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR001723", "url": "https://www.ebi.ac.uk/interpro/entry/IPR001723", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR013088", "url": "https://www.ebi.ac.uk/interpro/entry/IPR013088", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR035500", "url": "https://www.ebi.ac.uk/interpro/entry/IPR035500", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR049635", "url": "https://www.ebi.ac.uk/interpro/entry/IPR049635", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR049636", "url": "https://www.ebi.ac.uk/interpro/entry/IPR049636", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR050274", "url": "https://www.ebi.ac.uk/interpro/entry/IPR050274", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "WLTNETC", "url": "https://omabrowser.org/oma/group/WLTNETC/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "F1MGG2", "url": "https://www.orthodb.org/?gene=F1MGG2", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR24083", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR24083", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00104", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00104", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF00105", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00105", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "R-BTA-383280", "url": "https://www.reactome.org/PathwayBrowser/#R-BTA-383280", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "NP_001346854", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001346854", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0AAA9TTV4", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TTV4", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0AAA9TTV4-1", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TTV4-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "F1MGG2", "url": "https://www.uniprot.org/uniprotkb/F1MGG2", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "F1MGG2-1", "url": "https://www.uniprot.org/uniprotkb/F1MGG2-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MNTADNGVNCLCAICGDRATGKHYGASSCDGCKGFFRRSIRKSHVYSCRFSRQCVVDKDKRNQCRYCRLRKCFRAGMKKEAVQNERDRISTRRSTFDGSNIPSINTLAQAEVRSRQISVSSPGASADINVKKIASIGDVCESMKQQLLVLVEWAKYIPAFCELPLDDQVALLRAHAGEHLLLGATKRSMMYKDILLLGNNYVIHRNSCEVEISRVANRVLDELVRPFQEIQIDDNEYACLKAIVFFDPDAKGLSDPVKIKNMRFQVQLSLEDYINDRQYDSRGRFGELLLLLPTLQSITWQMIEQIQFVKLFGMVKIDNLLQEMLLGGASTEPNHLHHPMHPHLSQDPLTGQTILLGSMSTLVHTDQISTPETPLPSPPQGSGQEPYKIAANQASVISHQSLSKQKQL", "length": 408, "header": "tr|A0AAA9TTV4-1|A0AAA9TTV4_BOVIN Isoform 1 of Hepatocyte nuclear factor 4 gamma OS=Bos taurus OX=9913 GN=HNF4G PE=3 SV=2 CANONICAL=A0AAA9TTV4-1" }, "isoforms": [ { "isoform_ac": "A0AAA9TTV4-1", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TTV4/entry", "sequence": { "sequence": "MNTADNGVNCLCAICGDRATGKHYGASSCDGCKGFFRRSIRKSHVYSCRFSRQCVVDKDKRNQCRYCRLRKCFRAGMKKEAVQNERDRISTRRSTFDGSNIPSINTLAQAEVRSRQISVSSPGASADINVKKIASIGDVCESMKQQLLVLVEWAKYIPAFCELPLDDQVALLRAHAGEHLLLGATKRSMMYKDILLLGNNYVIHRNSCEVEISRVANRVLDELVRPFQEIQIDDNEYACLKAIVFFDPDAKGLSDPVKIKNMRFQVQLSLEDYINDRQYDSRGRFGELLLLLPTLQSITWQMIEQIQFVKLFGMVKIDNLLQEMLLGGASTEPNHLHHPMHPHLSQDPLTGQTILLGSMSTLVHTDQISTPETPLPSPPQGSGQEPYKIAANQASVISHQSLSKQKQL", "length": 408, "header": "tr|A0AAA9TTV4-1|A0AAA9TTV4_BOVIN Isoform 1 of Hepatocyte nuclear factor 4 gamma OS=Bos taurus OX=9913 GN=HNF4G PE=3 SV=2 CANONICAL=A0AAA9TTV4-1" }, "locus": { "chromosome": "14", "start_pos": 38828925, "end_pos": 38805686, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000090945.2", "url": "https://www.ensembl.org/id/ENSBTAT00000090945.2" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000102049.2", "url": "https://www.ensembl.org/id/ENSBTAP00000102049.2" } ] } }, { "isoform_ac": "F1MGG2-1", "url": "https://www.uniprot.org/uniprotkb/F1MGG2/entry", "sequence": { "sequence": "MCVSKSMMRVSEPILDMEMANYSEVLDPTYTTLEFDTMQILYNSNDSSVPETTSMNTADNGVNCLCAICGDRATGKHYGASSCDGCKGFFRRSIRKSHVYSCRFSRQCVVDKDKRNQCRYCRLRKCFRAGMKKEAVQNERDRISTRRSTFDGSNIPSINTLAQAEVRSRQISVSSPGASADINVKKIASIGDVCESMKQQLLVLVEWAKYIPAFCELPLDDQVALLRAHAGEHLLLGATKRSMMYKDILLLGNNYVIHRNSCEVEISRVANRVLDELVRPFQEIQIDDNEYACLKAIVFFDPDAKGLSDPVKIKNMRFQVQLSLEDYINDRQYDSRGRFGELLLLLPTLQSITWQMIEQIQFVKLFGMVKIDNLLQEMLLGGASTEPNHLHHPMHPHLSQDPLTGQTILLGSMSTLVHTDQISTPETPLPSPPQGSGQEPYKIAANQASVISHQSLSKQKQL", "length": 462, "header": "tr|F1MGG2-1|F1MGG2_BOVIN Computationally mapped isoform of Hepatocyte nuclear factor 4 gamma OS=Bos taurus OX=9913 GN=HNF4G PE=3 SV=3 CANONICAL=A0AAA9TTV4-1" }, "locus": { "chromosome": "14", "start_pos": 38828925, "end_pos": 38801792, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000010892.7", "url": "https://www.ensembl.org/id/ENSBTAT00000010892.7" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000010892.6", "url": "https://www.ensembl.org/id/ENSBTAP00000010892.6" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [ { "title": "Chicken ovalbumin upstream promoter transcription factor II (COUP-TFII) and hepatocyte nuclear factor 4gamma (HNF-4gamma) and HNF-4alpha regulate the bovine growth hormone receptor 1A promoter through a common DNA element.", "journal": "Journal of molecular endocrinology", "date": "2004-06", "authors": "Xu Q, Walther N, Jiang H", "evidence": [ { "database": "RefSeq", "id": "NP_001346854", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001346854" } ], "reference": [ { "type": "PubMed", "id": "15171724", "url": "https://glygen.org/publication/PubMed/15171724" } ] }, { "title": "A marker-derived gene network reveals the regulatory role of PPARGC1A, HNF4G, and FOXP3 in intramuscular fat deposition of beef cattle.", "journal": "Journal of animal science", "date": "2014-07", "authors": "Ramayo-Caldas Y, Fortes M R S, Hudson N J, Porto-Neto L R, Bolormaa S, Barendse W, Kelly M, Moore S S, Goddard M E, Lehnert S A, Reverter A", "evidence": [ { "database": "RefSeq", "id": "NP_001346854", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001346854" } ], "reference": [ { "type": "PubMed", "id": "24778332", "url": "https://glygen.org/publication/PubMed/24778332" } ] } ], "pathway": [ { "id": "R-BTA-383280", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-BTA-383280", "resource": "Reactome", "description": "Nuclear Receptor transcription pathway" } ], "orthologs": [ { "uniprot_canonical_ac": "A0A0R4IJK6-1", "protein_name": "Hepatocyte nuclear factor 4-gamma isoform X1", "gene_name": "hnf4g", "tax_id": 7955, "organism": "Danio rerio", "sequence": { "sequence": "MKFSPTPLPKSLLDMDVANYCEGLDPTYSTLGFENAEVLYCGENMPTEPNISQGENGVSSNCAICGDKATGKHYGASSCDGCKGFFRRSIRKSHVYSCRFNRQCVVDKDKRNQCRFCRLHKCFRAGMKKEAVQNERDRISSRRNIQDSHDLPPITALAHAEALSQQQITAASPMGPADVSEKKSATISDVCESMKQQLLVLVEWAKYIPAFGELPLDDQVSLLRAHAGEHLLLGVAKRSMSYKDLLLLGNGCVIHRNCPEPEIGRVSNRVLDELVLPFQDIQIDDNEYAALKAIVFFDPDAKSLRDPSKIKAMRYQVQMSLEDYINDRQYDSRGRFGELLLLLPTLQSITWQMIEQLQFIKLFGLAKIDNLLQEMLLGGLTTEQPHLHHNGHPQIPITGQTIVISSIPGPAHPQMASPETPIPSPTSVQNQEVFKPSGSPALLLPPQTMPNRPSPEPPL", "length": 459 }, "evidence": [ { "id": "A0AAA9TTV4", "url": "https://omabrowser.org/oma/group/A0AAA9TTV4/", "database": "OMA" } ], "glygen_name": "Zebrafish", "common_name": "Zebrafish" }, { "uniprot_canonical_ac": "A0A286ZIS6-1", "protein_name": "Hepatocyte nuclear factor 4 gamma", "gene_name": "HNF4G", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MNTADNGVNCLCAICGDRATGKHYGASSCDGCKGFFRRSIRKSHVYSCRFSRQCVVDKDKRNQCRYCRLRKCFRAGMKKEAVQNERDRISTRRSTFDGSNIPSINTLAQAEVRSRQISVPSPGASTDINVKKIASISDVCESMKQQLLVLVEWAKYIPAFCELPLDDQVALLRAHAGEHLLLGATKRSMAYKDILLLGNNYVIHRNSCEVEISRVANRVLDELVRPFQEIQIDDNEYACLKAIVFFDPDAKGLSDPVKIKNMRFQVQLSLEDYINDRQYDSRGRFGELLLLLPTLQSITWQMIEQIQFVKLFGMVKIDNLLQEMLLGGASSDTNHLHHPMHPHLSQDPLTGQTILLGPMSTLVHTDQISTPETPLPSPPQGSGQEPYKIAANQASVISHQPLSKQKQL", "length": 408 }, "evidence": [ { "id": "A0AAA9TTV4", "url": "https://omabrowser.org/oma/group/A0AAA9TTV4/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "A0A8V0XE41-1", "protein_name": "Hepatocyte nuclear factor 4 gamma", "gene_name": "HNF4G", "tax_id": 9031, "organism": "Gallus gallus", "sequence": { "sequence": "MMRVSEPILDMEMANYSEVLDPTYTTLEFETMQILYNGNDSSGEPLNMNATDSGISSLCAICGDRATGKHYGASSCDGCKGFFRRSIRKNHVYTCRFSRQCVVDKDKRNQCRYCRLKKCFRAGMKKEAVQNERDRISTRRNTFDGCNIPSISTLSQAEALSRQISVSSPGASTDINAKKIAGISDVCESMKQQLLVLVEWAKYIPGFCELPLDDQVALLRAHAGEHLLLGAAKRSMAYKDILLLGNNYIIHRNSTEVEISRVANRILDELVRPFQEIQIDDNEYACLKAIVFFDPDAKGLSNPVKIKNMRYQVQISLEDYINDRQYDSRGRFGELLLLLPTLQSITWQMIEQIQLVKLFGIVKIDSLLQEMLLGGTSNDASHLHHPVHPHLAQDPLTGQTILISSMSAPVHAEQISTPETPLPSPPQGSGQEYKMSSNQASEWGDSSGFPGTWTNHQL", "length": 458 }, "evidence": [ { "id": "A0AAA9TTV4", "url": "https://omabrowser.org/oma/group/A0AAA9TTV4/", "database": "OMA" } ], "glygen_name": "Chicken", "common_name": "Chicken" }, { "uniprot_canonical_ac": "F1M342-1", "protein_name": "Hepatocyte nuclear factor 4, gamma", "gene_name": "Hnf4g", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MNTTDSGVNCLCAICGDRATGKHYGASSCDGCKGFFRRSIRKSHVYSCRFSRQCVVDKDKRNQCRYCRLRKCFRAGMKKEAVQNERDRISTRRSTYEGTNIPSINTLAQAEVRSCQISVPNPSASTDINVKKIASISDVCESMKQQLLVLVEWAKYIPAFCELPLDDQVALLRAHAGEHLLLGATKRSMMYKDILLLGNHYVIHRNSCEVEVSRVANRVLDELVRPFQEIQIDDNEYACLKAIVFFDPDAKGLSDPGKIKNMRFQVQISLEDYINDRQYDSRGRFGELLLLLPTLQSITWQMIEQIQFVKLFGMVKIDNLLQEMLLGGAANDGGHPHHPMHPHLSQDPLTGQTILLGPMSTLVHTDQIATPETPLPSPPQGSGQEQYKITANQASVISHQPLSKQKQL", "length": 408 }, "evidence": [ { "id": "A0AAA9TTV4", "url": "https://omabrowser.org/oma/group/A0AAA9TTV4/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "Q14541-1", "protein_name": "Hepatocyte nuclear factor 4-gamma", "gene_name": "HNF4G", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MNTTDNGVNCLCAICGDRATGKHYGASSCDGCKGFFRRSIRKSHVYSCRFSRQCVVDKDKRNQCRYCRLRKCFRAGMKKEAVQNERDRISTRRSTFDGSNIPSINTLAQAEVRSRQISVSSPGSSTDINVKKIASIGDVCESMKQQLLVLVEWAKYIPAFCELPLDDQVALLRAHAGEHLLLGATKRSMMYKDILLLGNNYVIHRNSCEVEISRVANRVLDELVRPFQEIQIDDNEYACLKAIVFFDPDAKGLSDPVKIKNMRFQVQIGLEDYINDRQYDSRGRFGELLLLLPTLQSITWQMIEQIQFVKLFGMVKIDNLLQEMLLGGASNDGSHLHHPMHPHLSQDPLTGQTILLGPMSTLVHADQISTPETPLPSPPQGSGQEQYKIAANQASVISHQHLSKQKQL", "length": 408 }, "evidence": [ { "id": "A0AAA9TTV4", "url": "https://omabrowser.org/oma/group/A0AAA9TTV4/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "Q9WUU6-1", "protein_name": "Hepatocyte nuclear factor 4-gamma", "gene_name": "Hnf4g", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MNTTDSGVNCLCAICGDRATGKHYGASSCDGCKGFFRRSIRKSHVYSCRFSRQCVVDKDKRNQCRYCRLRKCFRAGMKKEAVQNERDRISTRRSTYEGSNIPSINTLAQAEVRSCQISVPSPSSSTDINIKKIASISDVCESMKQQLLVLVEWAKYIPAFCELPLDDQVALLRAHAGEHLLLGATKRSMMYKDILLLGNHYVIHRNSCEVEVSRVANRVLDELVRPFQEIQIDDNEYACLKAIVFFDPDAKGLSDPVKIKNMRFQVQISLEDYINDRQYDSRGRFGELLLLLPTLQSITWQMIEQIQFVKLFGMVKIDNLLQEMLLGGAANDGSHLHHPMHPHLSQDPLTGQTILLGPMSTLVHTDQIATPETPLPSPPQGSGQEPYKITANQASVISHQSLSKQKQL", "length": 408 }, "evidence": [ { "id": "A0AAA9TTV4", "url": "https://omabrowser.org/oma/group/A0AAA9TTV4/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" } ], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 3, "go_terms": [ { "name": "nucleus", "id": "GO:0005634", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005634", "evidence": [ { "database": "UniProtKB", "id": "A0AAA9TTV4", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TTV4" } ], "pmid": "" }, { "name": "nucleoplasm", "id": "GO:0005654", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005654", "evidence": [ { "database": "UniProtKB", "id": "A0AAA9TTV4", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TTV4" } ], "pmid": "" }, { "name": "cytosol", "id": "GO:0005829", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005829", "evidence": [ { "database": "UniProtKB", "id": "A0AAA9TTV4", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TTV4" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 3, "go_terms": [ { "name": "DNA-templated transcription", "id": "GO:0006351", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006351", "evidence": [ { "database": "UniProtKB", "id": "A0AAA9TTV4", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TTV4" } ], "pmid": "" }, { "name": "cell differentiation", "id": "GO:0030154", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030154", "evidence": [ { "database": "UniProtKB", "id": "A0AAA9TTV4", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TTV4" } ], "pmid": "" }, { "name": "positive regulation of transcription by RNA polymerase II", "id": "GO:0045944", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0045944", "evidence": [ { "database": "UniProtKB", "id": "A0AAA9TTV4", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TTV4" } ], "pmid": "" } ] }, { "name": "Molecular Function", "total": 4, "go_terms": [ { "name": "zinc ion binding", "id": "GO:0008270", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008270", "evidence": [ { "database": "UniProtKB", "id": "A0AAA9TTV4", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TTV4" } ], "pmid": "" }, { "name": "nuclear steroid receptor activity", "id": "GO:0003707", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003707", "evidence": [ { "database": "UniProtKB", "id": "A0AAA9TTV4", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TTV4" } ], "pmid": "" }, { "name": "RNA polymerase II cis-regulatory region sequence-specific DNA binding", "id": "GO:0000978", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000978", "evidence": [ { "database": "UniProtKB", "id": "A0AAA9TTV4", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TTV4" } ], "pmid": "" }, { "name": "nuclear receptor activity", "id": "GO:0004879", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0004879", "evidence": [ { "database": "UniProtKB", "id": "A0AAA9TTV4", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TTV4" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A0AAA9TTV4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TTV4" }, { "id": "PS51843", "database": "PROSITE", "url": "https://prosite.expasy.org/PS51843" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "NR LBD", "eco_id": "ECO_0000259", "start_pos": 99, "end_pos": 328, "start_aa": "Ser", "end_aa": "Gly", "glycosite_overlap": [] }, { "evidence": [ { "id": "A0AAA9TTV4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TTV4" }, { "id": "PS51030", "database": "PROSITE", "url": "https://prosite.expasy.org/PS51030" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "Nuclear receptor", "eco_id": "ECO_0000259", "start_pos": 9, "end_pos": 84, "start_aa": "Asn", "end_aa": "Asn", "glycosite_overlap": [] } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" }, { "name": "homologset.oma", "label": "OMA Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 2 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ], "tool_support": { "graph_view": "yes" } }, { "uniprot_canonical_ac": "A0AAA9TV02-1", "uniprot_ac": "A0AAA9TV02", "uniprot_id": "A0AAA9TV02_BOVIN", "mass": { "chemical_mass": 62054.0, "monoisotopic_mass": 62054.0 }, "refseq": { "ac": "XP_002693569", "name": "excitatory amino acid transporter 2 isoform X2", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_002693569" }, "gene_names": [ { "name": "SLC1A2", "type": "recommended", "evidence": [ { "id": "A0AAA9TV02", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TV02" } ] }, { "name": "SLC1A2", "type": "synonym", "evidence": [ { "id": "XP_002693569", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_002693569" } ] } ], "protein_names": [ { "name": "Amino acid transporter", "type": "recommended", "evidence": [ { "id": "A0AAA9TV02", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TV02/entry#names_and_taxonomy" } ] }, { "name": "excitatory amino acid transporter 2 isoform X2", "type": "synonym", "evidence": [ { "id": "XP_002693569", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_002693569" } ] } ], "function": [], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Bos taurus", "taxid": 9913, "evidence": [ { "database": "UniProtKB", "id": "A0AAA9TV02", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TV02" } ], "common_name": "Bovine", "glygen_name": "Bovine", "reference_species": "Bos taurus [9913]" } ], "gene": [ { "name": "SLC1A2", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TV02", "locus": { "chromosome": "15", "start_pos": 65775405, "end_pos": 65936554, "strand": "+", "evidence": [ { "database": "Ensembl Gene", "id": "ENSBTAG00000012628", "url": "https://www.ensembl.org/id/ENSBTAG00000012628" } ] } } ], "crossref": [ { "id": "A0AAA9TV02", "url": "https://alphafold.ebi.ac.uk/entry/A0AAA9TV02", "database": "AlphaFoldDB", "categories": [] }, { "id": "ENSBTAG00000012628", "url": "https://bgee.org/?page=gene&gene_id=ENSBTAG00000012628", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "541119", "url": "https://www.ncbi.nlm.nih.gov/gene/541119", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR001991", "url": "https://www.ebi.ac.uk/interpro/entry/IPR001991", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR018107", "url": "https://www.ebi.ac.uk/interpro/entry/IPR018107", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR036458", "url": "https://www.ebi.ac.uk/interpro/entry/IPR036458", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR050746", "url": "https://www.ebi.ac.uk/interpro/entry/IPR050746", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "bta:541119", "url": "https://www.genome.jp/dbget-bin/www_bget?bta:541119", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "TWTKEID", "url": "https://omabrowser.org/oma/group/TWTKEID/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "A0A3Q1LFK0", "url": "https://www.orthodb.org/?gene=A0A3Q1LFK0", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A3Q1M3C0", "url": "https://www.orthodb.org/?gene=A0A3Q1M3C0", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A3Q1MR13", "url": "https://www.orthodb.org/?gene=A0A3Q1MR13", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A3Q1MV72", "url": "https://www.orthodb.org/?gene=A0A3Q1MV72", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "F1MUJ6", "url": "https://www.orthodb.org/?gene=F1MUJ6", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR11958", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR11958", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR11958:SF93", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR11958:SF93", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00375", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00375", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "R-BTA-210455", "url": "https://www.reactome.org/PathwayBrowser/#R-BTA-210455", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "R-BTA-210500", "url": "https://www.reactome.org/PathwayBrowser/#R-BTA-210500", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "R-BTA-9958863", "url": "https://www.reactome.org/PathwayBrowser/#R-BTA-9958863", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "XP_002693569", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_002693569", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "70699", "url": "https://www.rhea-db.org/rhea/70699", "database": "Rhea", "categories": [ "Enzyme and Pathway" ] }, { "id": "70851", "url": "https://www.rhea-db.org/rhea/70851", "database": "Rhea", "categories": [ "Enzyme and Pathway" ] }, { "id": "71379", "url": "https://www.rhea-db.org/rhea/71379", "database": "Rhea", "categories": [ "Enzyme and Pathway" ] }, { "id": "A0A3Q1LFK0", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1LFK0", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A3Q1LFK0-1", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1LFK0-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A3Q1M3C0", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1M3C0", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A3Q1M3C0-1", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1M3C0-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A3Q1MR13", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1MR13", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A3Q1MR13-1", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1MR13-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A3Q1MV72", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1MV72", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A3Q1MV72-1", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1MV72-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0AAA9S3R5", "url": "https://www.uniprot.org/uniprotkb/A0AAA9S3R5", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0AAA9S3R5-1", "url": "https://www.uniprot.org/uniprotkb/A0AAA9S3R5-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0AAA9SGE9", "url": "https://www.uniprot.org/uniprotkb/A0AAA9SGE9", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0AAA9SGE9-1", "url": "https://www.uniprot.org/uniprotkb/A0AAA9SGE9-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0AAA9SJB6", "url": "https://www.uniprot.org/uniprotkb/A0AAA9SJB6", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0AAA9SJB6-1", "url": "https://www.uniprot.org/uniprotkb/A0AAA9SJB6-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0AAA9TEA5", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TEA5", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0AAA9TEA5-1", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TEA5-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0AAA9TV02", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TV02", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0AAA9TV02-1", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TV02-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "F1MUJ6", "url": "https://www.uniprot.org/uniprotkb/F1MUJ6", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "F1MUJ6-1", "url": "https://www.uniprot.org/uniprotkb/F1MUJ6-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MASTEGANNMPKQVEVRMHDSHLSAEEPKPRHLGLRLCDKLGKNLLLTLTVFGVILGAVCGGLLRLASPIHPDVVMLIAFPGDILMRMLKMLILPLIISSLITGLSGLDAKASGRLGTRAMVYYMSTTIIAAVLGVILVLAIHPGNPKLKKQLGPGKKNDEVSSLDAFLDLIRNLFPENLVQACFQQIQTVTKKVLVAPPSDEDGNATNAVLSLLNETVTEVPEETQVVIKKGLEFKDGMNVLGLIGFFIAFGIAMGKMGEQAKLMVEFFNILNEIVMKLVIMIMWYSPLGIACLICGKIIAIKDLEVVARQLGMYMITVIVGLIIHGGIFLPLIYFLVTRKNPFSFFAGIFQAWITALGTASSAGTLPVTFRCLEENLGIDKRVTRFVLPVGATINMDGTALYEAVAAIFIAQMNGVVLDGGQIVTVSLTATLASVGAASIPSAGLVTMLLILTAVGLPTEDISLLVAVDWLLDRMRTSVNVVGDSFGAGIVYHLSKSELDTIDSQHRVHEDIEMTKTQSIYDDLKNHRESNSNQCVYAAHNSVIVDECKVTLAANGKSADCSVEEEPWKHEK", "length": 574, "header": "tr|A0AAA9TV02-1|A0AAA9TV02_BOVIN Isoform 1 of Amino acid transporter OS=Bos taurus OX=9913 GN=SLC1A2 PE=3 SV=1 CANONICAL=A0AAA9TV02-1" }, "isoforms": [ { "isoform_ac": "A0A3Q1LFK0-1", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1LFK0/entry", "sequence": { "sequence": "MDANNMPKQVEVRMHDSHLSAEEPKPRHLGLRLCDKLGKNLLLTLTVFGVILGAVCGGLLRLASPIHPDVVMLIAFPGDILMRMLKMLILPLIISSLITGLSGLDAKASGRLGTRAMVYYMSTTIIAAVLGVILVLAIHPGNPKLKKQLGPGKKNDEVSSLDAFLDLIRNLFPENLVQACFQQIQTVTKKVLVAPPSDEDGNATNAVLSLLNETVTEVPEETQVVIKKGLEFKDGMNVLGLIGFFIAFGIAMGKMGEQAKLMVEFFNILNEIVMKLVIMIMWYSPLGIACLICGKIIAIKDLEVVARQLGMYMITVIVGLIIHGGIFLPLIYFLVTRKNPFSFFAGIFQAWITALGTASSAGTLPVTFRCLEENLGIDKRVTRFVLPVGATINMDGTALYEAVAAIFIAQMNGVVLDGGQIVTVSLTATLASVGAASIPSAGLVTMLLILTAVGLPTEDISLLVAVDWLLDRMRTSVNVVGDSFGAGIVYHLSKSELDTIDSQHRVHEDIEMTKTQSIYDDLKNHRESNSNQCVYAAHNSVIVDECKVTLAANGKSADCSVEEEPWKHEK", "length": 570, "header": "tr|A0A3Q1LFK0-1|A0A3Q1LFK0_BOVIN Computationally mapped isoform of Amino acid transporter OS=Bos taurus OX=9913 GN=SLC1A2 PE=3 SV=2 CANONICAL=A0AAA9TV02-1" }, "locus": { "chromosome": "15", "start_pos": 65936554, "end_pos": 65776409, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000074655.2", "url": "https://www.ensembl.org/id/ENSBTAT00000074655.2" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000056967.2", "url": "https://www.ensembl.org/id/ENSBTAP00000056967.2" } ] } }, { "isoform_ac": "A0A3Q1M3C0-1", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1M3C0/entry", "sequence": { "sequence": "MPKQVEVRMHDSHLSAEEPKPRHLGLRLCDKLGKNLLLTLTVFGVILGAVCGGLLRLASPIHPDVVMLIAFPGDILMRMLKMLILPLIISSLITGLSGLDAKASGRLGTRAMVYYMSTTIIAAVLGVILVLAIHPGNPKLKKQLGPGKKNDEVSSLDAFLDLIRNLFPENLVQACFQQIQTVTKKVLVAPPSDEDGNATNAVLSLLNETVTEVPEETQVVIKKGLEFKDGMNVLGLIGFFIAFGIAMGKMGEQAKLMVEFFNILNEIVMKLVIMIMWYSPLGIACLICGKIIAIKDLEVVARQLGMYMITVIVGLIIHGGIFLPLIYFLVTRKNPFSFFAGIFQAWITALGTASSAGTLPVTFRCLEENLGIDKRVTRFVLPVGATINMDGTALYEAVAAIFIAQMNGVVLDGGQIVTVSLTATLASVGAASIPSAGLVTMLLILTAVGLPTEDISLLVAVDWLLDRMRTSVNVVGDSFGAGIVYHLSKSELDTIDSQHRVHEDIEMTKTQSIYDDLKNHRESNSNQCVYAAHNSVIVDECKVPFPFMDIETCI", "length": 554, "header": "tr|A0A3Q1M3C0-1|A0A3Q1M3C0_BOVIN Computationally mapped isoform of Amino acid transporter OS=Bos taurus OX=9913 GN=SLC1A2 PE=3 SV=2 CANONICAL=A0AAA9TV02-1" }, "locus": { "chromosome": "15", "start_pos": 65832727, "end_pos": 65780344, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000076205.2", "url": "https://www.ensembl.org/id/ENSBTAT00000076205.2" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000064602.2", "url": "https://www.ensembl.org/id/ENSBTAP00000064602.2" } ] } }, { "isoform_ac": "A0A3Q1MR13-1", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1MR13/entry", "sequence": { "sequence": "MPALRGQRIPGDESMVSANNMPKQVEVRMHDSHLSAEEPKPRHLGLRLCDKLGKNLLLTLTVFGVILGAVCGGLLRLASPIHPDVVMLIAFPGDILMRMLKMLILPLIISSLITGLSGLDAKASGRLGTRAMVYYMSTTIIAAVLGVILVLAIHPGNPKLKKQLGPGKKNDEVSSLDAFLDLIRNLFPENLVQACFQQIQTVTKKVLVAPPSDEDGNATNAVLSLLNETVTEVPEETQVVIKKGLEFKDGMNVLGLIGFFIAFGIAMGKMGEQAKLMVEFFNILNEIVMKLVIMIMWYSPLGIACLICGKIIAIKDLEVVARQLGMYMITVIVGLIIHGGIFLPLIYFLVTRKNPFSFFAGIFQAWITALGTASSAGTLPVTFRCLEENLGIDKRVTRFVLPVGATINMDGTALYEAVAAIFIAQMNGVVLDGGQIVTVSLTATLASVGAASIPSAGLVTMLLILTAVGLPTEDISLLVAVDWLLDRMRTSVNVVGDSFGAGIVYHLSKSELDTIDSQHRVHEDIEMTKTQSIYDDLKNHRESNSNQCVYAAHNSVIVDECKLSDRVQLCGDREVRQLTLLVLDQSAGLTPMHRGGSQSYRDEFAGFTQSIGVTFTPAFETLSGSVWFSKGTTLRFMMLHSC", "length": 642, "header": "tr|A0A3Q1MR13-1|A0A3Q1MR13_BOVIN Computationally mapped isoform of Amino acid transporter OS=Bos taurus OX=9913 GN=SLC1A2 PE=3 SV=2 CANONICAL=A0AAA9TV02-1" }, "locus": { "chromosome": "15", "start_pos": 65879293, "end_pos": 65777762, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000069455.2", "url": "https://www.ensembl.org/id/ENSBTAT00000069455.2" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000074103.2", "url": "https://www.ensembl.org/id/ENSBTAP00000074103.2" } ] } }, { "isoform_ac": "A0A3Q1MV72-1", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1MV72/entry", "sequence": { "sequence": "MASTEGANNMPKQVEVRMHDSHLSAEEPKPRHLGLRLCDKLGKNLLLTLTVFGVILGAVCGGLLRLASPIHPDVVMLIAFPGDILMRMLKMLILPLIISSLITGLSGLDAKASGRLGTRAMVYYMSTTIIAAVLGVILVLAIHPGNPKLKKQLGPGKKNDEVSSLDAFLDLIRNLFPENLVQACFQQIQTVTKKVLVAPPSDEDGNATNAVLSLLNETVTEVPEETQVVIKKGLEFKDGMNVLGLIGFFIAFGIAMGKMGEQAKLMVEFFNILNEIVMKLVIMIMCAGTLPVTFRCLEENLGIDKRVTRFVLPVGATINMDGTALYEAVAAIFIAQMNGVVLDGGQIVTVSLTATLASVGAASIPSAGLVTMLLILTAVGLPTEDISLLVAVDWLLDRMRTSVNVVGDSFGAGIVYHLSKSELDTIDSQHRVHEDIEMTKTQSIYDDLKNHRESNSNQCVYAAHNSVIVDECKVTLAANGKSADCSVEEEPWKHEK", "length": 496, "header": "tr|A0A3Q1MV72-1|A0A3Q1MV72_BOVIN Computationally mapped isoform of Amino acid transporter OS=Bos taurus OX=9913 GN=SLC1A2 PE=3 SV=2 CANONICAL=A0AAA9TV02-1" }, "locus": { "chromosome": "15", "start_pos": 65935522, "end_pos": 65776409, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000075326.3", "url": "https://www.ensembl.org/id/ENSBTAT00000075326.3" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000058834.2", "url": "https://www.ensembl.org/id/ENSBTAP00000058834.2" } ] } }, { "isoform_ac": "A0AAA9S3R5-1", "url": "https://www.uniprot.org/uniprotkb/A0AAA9S3R5/entry", "sequence": { "sequence": "MEFSKQEHWNGLPFPSPGDLLDPGIELVSLVSPVLTGGFLTAGATGEAHHANNMPKQVEVRMHDSHLSAEEPKPRHLGLRLCDKLGKNLLLTLTVFGVILGAVCGGLLRLASPIHPDVVMLIAFPGDILMRMLKMLILPLIISSLITGLSGLDAKASGRLGTRAMVYYMSTTIIAAVLGVILVLAIHPGNPKLKKQLGPGKKNDEVSSLDAFLDLIRNLFPENLVQACFQQIQTVTKKVLVAPPSDEDGNATNAVLSLLNETVTEVPEETQVVIKKGLEFKDGMNVLGLIGFFIAFGIAMGKMGEQAKLMVEFFNILNEIVMKLVIMIMWYSPLGIACLICGKIIAIKDLEVVARQLGMYMITVIVGLIIHGGIFLPLIYFLVTRKNPFSFFAGIFQAWITALGTASSAGTLPVTFRCLEENLGIDKRVTRFVLPVGATINMDGTALYEAVAAIFIAQMNGVVLDGGQIVTVSLTATLASVGAASIPSAGLVTMLLILTAVGLPTEDISLLVAVDWLLDRMRTSVNVVGDSFGAGIVYHLSKSELDTIDSQHRVHEDIEMTKTQSIYDDLKNHRESNSNQCVYAAHNSVIVDECKVTLAANGKSADCSVEEEPWKHEK", "length": 618, "header": "tr|A0AAA9S3R5-1|A0AAA9TV02_BOVIN Computationally mapped isoform of Amino acid transporter OS=Bos taurus OX=9913 GN=SLC1A2 PE=3 SV=1 CANONICAL=A0AAA9TV02-1" }, "locus": { "chromosome": "15", "start_pos": 65881504, "end_pos": 65776409, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000096183.1", "url": "https://www.ensembl.org/id/ENSBTAT00000096183.1" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000078429.1", "url": "https://www.ensembl.org/id/ENSBTAP00000078429.1" } ] } }, { "isoform_ac": "A0AAA9SGE9-1", "url": "https://www.uniprot.org/uniprotkb/A0AAA9SGE9/entry", "sequence": { "sequence": "MPKQVEVRMHDSHLSAEEPKPRHLGLRLCDKLGKNLLLTLTVFGVILGAVCGGLLRLASPIHPDVVMLIAFPGDILMRMLKMLILPLIISSLITGLSGLDAKASGRLGTRAMVYYMSTTIIAAVLGVILVLAIHPGNPKLKKQLGPGKKNDEVSSLDAFLDLIRNLFPENLVQACFQQIQTVTKKVLVAPPSDEDGNATNAVLSLLNETVTEVPEETQVVIKKGLEFKDGMNVLGLIGFFIAFGIAMGKMGEQAKLMVEFFNILNEIVMKLVIMIMWYSPLGIACLICGKIIAIKDLEVVARQLGMYMITVIVGLIIHGGIFLPLIYFLVTRKNPFSFFAGIFQAWITALGTASSAGTLPVTFRCLEENLGIDKRVTRFVLPVGATINMDGTALYEAVAAIFIAQMNGVVLDGGQIVTVSLTATLASVGAASIPSAGLVTMLLILTAVGLPTEDISLLVAVDWLLDRMRTSVNVVGDSFGAGIVYHLSKSELDTIDSQHRVHEDIEMTKTQSIYDDLKNHRESNSNQCVYAAHNSVIVDECKVTLAANGKSADCSVEEEPWKHEK", "length": 565, "header": "tr|A0AAA9SGE9-1|A0AAA9TV02_BOVIN Computationally mapped isoform of Amino acid transporter OS=Bos taurus OX=9913 GN=SLC1A2 PE=3 SV=1 CANONICAL=A0AAA9TV02-1" }, "locus": { "chromosome": "15", "start_pos": 65832727, "end_pos": 65776409, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000114263.1", "url": "https://www.ensembl.org/id/ENSBTAT00000114263.1" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000082950.1", "url": "https://www.ensembl.org/id/ENSBTAP00000082950.1" } ] } }, { "isoform_ac": "A0AAA9SJB6-1", "url": "https://www.uniprot.org/uniprotkb/A0AAA9SJB6/entry", "sequence": { "sequence": "MPALRGQRIPGDESMVSANNMPKQVEVRMHDSHLSAEEPKPRHLGLRLCDKLGKNLLLTLTVFGVILGAVCGGLLRLASPIHPDVVMLIAFPGDILMRMLKMLILPLIISSLITGLSGLDAKASGRLGTRAMVYYMSTTIIAAVLGVILVLAIHPGNPKLKKQLGPGKKNDEVSSLDAFLDLIRNLFPENLVQACFQQIQTVTKKVLVAPPSDEDGNATNAVLSLLNETVTEVPEETQVVIKKGLEFKDGMNVLGLIGFFIAFGIAMGKMGEQAKLMVEFFNILNEIVMKLVIMIMWYSPLGIACLICGKIIAIKDLEVVARQLGMYMITVIVGLIIHGGIFLPLIYFLVTRKNPFSFFAGIFQAWITALGTASSAGTLPVTFRCLEENLGIDKRVTRFVLPVGATINMDGTALYEAVAAIFIAQMNGVVLDGGQIVTVSLTATLASVGAASIPSAGLVTMLLILTAVGLPTEDISLLVAVDWLLDRMRTSVNVVGDSFGAGIVYHLSKSELDTIDSQHRVHEDIEMTKTQSIYDDLKNHRESNSNQCVYAAHNSVIVDECKVTLAANGKSADCSVEEEPWKHEK", "length": 585, "header": "tr|A0AAA9SJB6-1|A0AAA9TV02_BOVIN Computationally mapped isoform of Amino acid transporter OS=Bos taurus OX=9913 GN=SLC1A2 PE=3 SV=1 CANONICAL=A0AAA9TV02-1" }, "locus": { "chromosome": "15", "start_pos": 65879293, "end_pos": 65776409, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000113013.1", "url": "https://www.ensembl.org/id/ENSBTAT00000113013.1" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000086360.1", "url": "https://www.ensembl.org/id/ENSBTAP00000086360.1" } ] } }, { "isoform_ac": "A0AAA9TEA5-1", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TEA5/entry", "sequence": { "sequence": "MKTPQDPIRRSANNMPKQVEVRMHDSHLSAEEPKPRHLGLRLCDKLGKNLLLTLTVFGVILGAVCGGLLRLASPIHPDVVMLIAFPGDILMRMLKMLILPLIISSLITGLSGLDAKASGRLGTRAMVYYMSTTIIAAVLGVILVLAIHPGNPKLKKQLGPGKKNDEVSSLDAFLDLIRNLFPENLVQACFQQIQTVTKKVLVAPPSDEDGNATNAVLSLLNETVTEVPEETQVVIKKGLEFKDGMNVLGLIGFFIAFGIAMGKMGEQAKLMVEFFNILNEIVMKLVIMIMWYSPLGIACLICGKIIAIKDLEVVARQLGMYMITVIVGLIIHGGIFLPLIYFLVTRKNPFSFFAGIFQAWITALGTASSAGTLPVTFRCLEENLGIDKRVTRFVLPVGATINMDGTALYEAVAAIFIAQMNGVVLDGGQIVTVSLTATLASVGAASIPSAGLVTMLLILTAVGLPTEDISLLVAVDWLLDRMRTSVNVVGDSFGAGIVYHLSKSELDTIDSQHRVHEDIEMTKTQSIYDDLKNHRESNSNQCVYAAHNSVIVDECKVTLAANGKSADCSVEEEPWKHEK", "length": 579, "header": "tr|A0AAA9TEA5-1|A0AAA9TV02_BOVIN Computationally mapped isoform of Amino acid transporter OS=Bos taurus OX=9913 GN=SLC1A2 PE=3 SV=1 CANONICAL=A0AAA9TV02-1" }, "locus": { "chromosome": "15", "start_pos": 65899308, "end_pos": 65776409, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000125301.1", "url": "https://www.ensembl.org/id/ENSBTAT00000125301.1" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000094506.1", "url": "https://www.ensembl.org/id/ENSBTAP00000094506.1" } ] } }, { "isoform_ac": "A0AAA9TV02-1", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TV02/entry", "sequence": { "sequence": "MASTEGANNMPKQVEVRMHDSHLSAEEPKPRHLGLRLCDKLGKNLLLTLTVFGVILGAVCGGLLRLASPIHPDVVMLIAFPGDILMRMLKMLILPLIISSLITGLSGLDAKASGRLGTRAMVYYMSTTIIAAVLGVILVLAIHPGNPKLKKQLGPGKKNDEVSSLDAFLDLIRNLFPENLVQACFQQIQTVTKKVLVAPPSDEDGNATNAVLSLLNETVTEVPEETQVVIKKGLEFKDGMNVLGLIGFFIAFGIAMGKMGEQAKLMVEFFNILNEIVMKLVIMIMWYSPLGIACLICGKIIAIKDLEVVARQLGMYMITVIVGLIIHGGIFLPLIYFLVTRKNPFSFFAGIFQAWITALGTASSAGTLPVTFRCLEENLGIDKRVTRFVLPVGATINMDGTALYEAVAAIFIAQMNGVVLDGGQIVTVSLTATLASVGAASIPSAGLVTMLLILTAVGLPTEDISLLVAVDWLLDRMRTSVNVVGDSFGAGIVYHLSKSELDTIDSQHRVHEDIEMTKTQSIYDDLKNHRESNSNQCVYAAHNSVIVDECKVTLAANGKSADCSVEEEPWKHEK", "length": 574, "header": "tr|A0AAA9TV02-1|A0AAA9TV02_BOVIN Isoform 1 of Amino acid transporter OS=Bos taurus OX=9913 GN=SLC1A2 PE=3 SV=1 CANONICAL=A0AAA9TV02-1" }, "locus": { "chromosome": "15", "start_pos": 65935522, "end_pos": 65776409, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000091036.1", "url": "https://www.ensembl.org/id/ENSBTAT00000091036.1" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000102446.1", "url": "https://www.ensembl.org/id/ENSBTAP00000102446.1" } ] } }, { "isoform_ac": "F1MUJ6-1", "url": "https://www.uniprot.org/uniprotkb/F1MUJ6/entry", "sequence": { "sequence": "MPKQVEVRMHDSHLSAEEPKPRHLGLRLCDKLGKNLLLTLTVFGVILGAVCGGLLRLASPIHPDVVMLIAFPGDILMRMLKMLILPLIISSLITGLSGLDAKASGRLGTRAMVYYMSTTIIAAVLGVILVLAIHPGNPKLKKQLGPGKKNDEVSSLDAFLDLIRNLFPENLVQACFQQIQTVTKKVLVAPPSDEDGNATNAVLSLLNETVTEVPEETQVVIKKGLEFKDGMNVLGLIGFFIAFGIAMGKMGEQAKLMVEFFNILNEIVMKLVIMIMWYSPLGIACLICGKIIAIKDLEVVARQLGMYMITVIVGLIIHGGIFLPLIYFLVTRKNPFSFFAGIFQAWITALGTASSAGTLPVTFRCLEENLGIDKRVTRFVLPVGATINMDGTALYEAVAAIFIAQMNGVVLDGGQIVTVSLTATLASVGAASIPSAGLVTMLLILTAVGLPTEDISLLVAVDWLLDRMRTSVNVVGDSFGAGIVYHLSKSELDTIDSQHRVHEDIEMTKTQSIYDDLKNHRESNSNQCVYAAHNSVIVDECKLSDRVQLCGDREVRQLTLLVLDQSAGLTPMHRGGSQSYRDEFAGFTQSIGVTFTPAFETLSGLFCSTVLKTELGTSVLSTSPLPFRLF", "length": 630, "header": "tr|F1MUJ6-1|F1MUJ6_BOVIN Computationally mapped isoform of Amino acid transporter OS=Bos taurus OX=9913 GN=SLC1A2 PE=3 SV=3 CANONICAL=A0AAA9TV02-1" }, "locus": { "chromosome": "15", "start_pos": 65832727, "end_pos": 65777989, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000016762.5", "url": "https://www.ensembl.org/id/ENSBTAT00000016762.5" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000016762.5", "url": "https://www.ensembl.org/id/ENSBTAP00000016762.5" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [ { "id": "bta:541119", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?bta:541119", "resource": "KEGG Pathway" }, { "id": "R-BTA-210455", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-BTA-210455", "resource": "Reactome", "description": "Astrocytic Glutamate-Glutamine Uptake And Metabolism" }, { "id": "R-BTA-210500", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-BTA-210500", "resource": "Reactome", "description": "Glutamate Neurotransmitter Release Cycle" }, { "id": "R-BTA-9958863", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-BTA-9958863", "resource": "Reactome", "description": "SLC-mediated transport of amino acids" } ], "orthologs": [ { "uniprot_canonical_ac": "A0A8V1A900-1", "protein_name": "Amino acid transporter", "gene_name": "SLC1A2", "tax_id": 9031, "organism": "Gallus gallus", "sequence": { "sequence": "MLGRAKGYTRGFEERHGARLDSGPETETCPHPRPYSRPCPCPTTGDQEDPLWSPYFAGEKLRREISFTYSGIKAGELRHRKDHQGNKFGTTRAVRGRLSIDAGAVEKSANNMPKQVEVRMHESHLSPVEHRSGNICVQFFKSLRRNLLLTLTVFGVILGALCGGLLRLATPIDPDIIMLIAFPGDILMRMLKMLILPLIISSLITGLSGLDAKASGRLGTRAMVYYMSTTIIAAVLGVILVLAIHPGNPKLKKQLGQGKKNDEVSSLDAFLDLIRNLFPENLVQACFQQIQTVTKKVLVPPPIEEPPNVTDSAFALMNETVREAPPEAQLVIKKGLEFKDGMNVLGLIGFFIAFGIAMGKMGDQAKMMVDFFNILNEIVMKLVTMIMWYSPLGIACLICGKIIAIKDLEVVARQLGMYMVTVIVGLVIHGGIFLPLLYFVITRKSPFSFLAGIFQAWITALGTASSAGTLPVTFRCLEENLGIDKRVTRFVLPVGATINMDGTALYEAVAAIFIAQMNGIELDGGQIVTVSLTATLASVGAASIPSAGLVTMLLILTAVGLPTQDISLLVAVDWLLDRMRTSVNVVGDSFGAGIVYHLSKAELDSIDSHHKEHEDIEMTKTQSIYDDMKNHRENNSNQCVFAAHNSVIVDECKVTLATNGKSADINVVEEEPWKREN", "length": 677 }, "evidence": [ { "id": "A0AAA9TV02", "url": "https://omabrowser.org/oma/group/A0AAA9TV02/", "database": "OMA" } ], "glygen_name": "Chicken", "common_name": "Chicken" }, { "uniprot_canonical_ac": "P31596-1", "protein_name": "Excitatory amino acid transporter 2", "gene_name": "Slc1a2", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MASTEGANNMPKQVEVRMHDSHLSSEEPKHRNLGMRMCDKLGKNLLLSLTVFGVILGAVCGGLLRLAAPIHPDVVMLIAFPGDILMRMLKMLILPLIISSLITGLSGLDAKASGRLGTRAMVYYMSTTIIAAVLGVILVLAIHPGNPKLKKQLGPGKKNDEVSSLDAFLDLIRNLFPENLVQACFQQIQTVTKKVLVAPPSEEANTTKAVISLLNETMNEAPEETKIVIKKGLEFKDGMNVLGLIGFFIAFGIAMGKMGEQAKLMVEFFNILNEIVMKLVIMIMWYSPLGIACLICGKIIAIKDLEVVARQLGMYMITVIVGLIIHGGIFLPLIYFVVTRKNPFSFFAGIFQAWITALGTASSAGTLPVTFRCLEDNLGIDKRVTRFVLPVGATINMDGTALYEAVAAIFIAQMNGVILDGGQIVTVSLTATLASIGAASIPSAGLVTMLLILTAVGLPTEDISLLVAVDWLLDRMRTSVNVVGDSFGAGIVYHLSKSELDTIDSQHRMHEDIEMTKTQSVYDDTKNHRESNSNQCVYAAHNSVVIDECKVTLAANGKSADCSVEEEPWKREK", "length": 573 }, "evidence": [ { "id": "A0AAA9TV02", "url": "https://omabrowser.org/oma/group/A0AAA9TV02/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "P43004-1", "protein_name": "Excitatory amino acid transporter 2", "gene_name": "SLC1A2", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MASTEGANNMPKQVEVRMHDSHLGSEEPKHRHLGLRLCDKLGKNLLLTLTVFGVILGAVCGGLLRLASPIHPDVVMLIAFPGDILMRMLKMLILPLIISSLITGLSGLDAKASGRLGTRAMVYYMSTTIIAAVLGVILVLAIHPGNPKLKKQLGPGKKNDEVSSLDAFLDLIRNLFPENLVQACFQQIQTVTKKVLVAPPPDEEANATSAVVSLLNETVTEVPEETKMVIKKGLEFKDGMNVLGLIGFFIAFGIAMGKMGDQAKLMVDFFNILNEIVMKLVIMIMWYSPLGIACLICGKIIAIKDLEVVARQLGMYMVTVIIGLIIHGGIFLPLIYFVVTRKNPFSFFAGIFQAWITALGTASSAGTLPVTFRCLEENLGIDKRVTRFVLPVGATINMDGTALYEAVAAIFIAQMNGVVLDGGQIVTVSLTATLASVGAASIPSAGLVTMLLILTAVGLPTEDISLLVAVDWLLDRMRTSVNVVGDSFGAGIVYHLSKSELDTIDSQHRVHEDIEMTKTQSIYDDMKNHRESNSNQCVYAAHNSVIVDECKVTLAANGKSADCSVEEEPWKREK", "length": 574 }, "evidence": [ { "id": "A0AAA9TV02", "url": "https://omabrowser.org/oma/group/A0AAA9TV02/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "P43006-1", "protein_name": "Excitatory amino acid transporter 2", "gene_name": "Slc1a2", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MASTEGANNMPKQVEVRMHDSHLSSDEPKHRNLGMRMCDKLGKNLLLSLTVFGVILGAVCGGLLRLASPIHPDVVMLIAFPGDILMRMLKMLILPLIISSLITGLSGLDAKASGRLGTRAMVYYMSTTIIAAVLGVILVLAIHPGNPKLKKQLGPGKKNDEVSSLDAFLDLIRNLFPENLVQACFQQIQTVTKKVLVAPPSEEANTTKAVISMLNETMNEAPEETKIVIKKGLEFKDGMNVLGLIGFFIAFGIAMGKMGEQAKLMVEFFNILNEIVMKLVIMIMWYSPLGIACLICGKIIAIKDLEVVARQLGMYMITVIVGLIIHGGIFLPLIYFVVTRKNPFSFFAGIFQAWITALGTASSAGTLPVTFRCLEDNLGIDKRVTRFVLPVGATINMDGTALYEAVAAIFIAQMNGVILDGGQIVTVSLTATLASIGAASIPSAGLVTMLLILTAVGLPTEDISLLVAVDWLLDRMRTSVNVVGDSFGAGIVYHLSKSELDTIDSQHRMQEDIEMTKTQSIYDDKNHRESNSNQCVYAAHNSVVIDECKVTLAANGKSADCSVEEEPWKREK", "length": 572 }, "evidence": [ { "id": "A0AAA9TV02", "url": "https://omabrowser.org/oma/group/A0AAA9TV02/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" } ], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 12, "go_terms": [ { "name": "membrane", "id": "GO:0016020", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016020", "evidence": [ { "database": "UniProtKB", "id": "A0AAA9TV02", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TV02" } ], "pmid": "" }, { "name": "glutamatergic synapse", "id": "GO:0098978", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0098978", "evidence": [ { "database": "UniProtKB", "id": "A0AAA9TV02", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TV02" } ], "pmid": "" }, { "name": "cell surface", "id": "GO:0009986", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0009986", "evidence": [ { "database": "UniProtKB", "id": "A0AAA9TV02", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TV02" } ], "pmid": "" }, { "name": "membrane raft", "id": "GO:0045121", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0045121", "evidence": [ { "database": "UniProtKB", "id": "A0AAA9TV02", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TV02" } ], "pmid": "" }, { "name": "astrocyte projection", "id": "GO:0097449", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0097449", "evidence": [ { "database": "UniProtKB", "id": "A0AAA9TV02", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TV02" } ], "pmid": "" }, { "name": "axolemma", "id": "GO:0030673", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030673", "evidence": [ { "database": "UniProtKB", "id": "A0AAA9TV02", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TV02" } ], "pmid": "" }, { "name": "cell body", "id": "GO:0044297", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0044297", "evidence": [ { "database": "UniProtKB", "id": "A0AAA9TV02", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TV02" } ], "pmid": "" }, { "name": "vesicle", "id": "GO:0031982", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0031982", "evidence": [ { "database": "UniProtKB", "id": "A0AAA9TV02", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TV02" } ], "pmid": "" }, { "name": "presynaptic membrane", "id": "GO:0042734", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0042734", "evidence": [ { "database": "UniProtKB", "id": "A0AAA9TV02", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TV02" } ], "pmid": "" }, { "name": "neuron projection terminus", "id": "GO:0044306", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0044306", "evidence": [ { "database": "UniProtKB", "id": "A0AAA9TV02", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TV02" } ], "pmid": "" }, { "name": "membrane protein complex", "id": "GO:0098796", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0098796", "evidence": [ { "database": "UniProtKB", "id": "A0AAA9TV02", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TV02" } ], "pmid": "" }, { "name": "plasma membrane", "id": "GO:0005886", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005886", "evidence": [ { "database": "UniProtKB", "id": "A0AAA9TV02", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TV02" } ], "pmid": "" } ] }, { "name": "Molecular Function", "total": 7, "go_terms": [ { "name": "symporter activity", "id": "GO:0015293", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0015293", "evidence": [ { "database": "UniProtKB", "id": "A0AAA9TV02", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TV02" } ], "pmid": "" }, { "name": "monoatomic anion transmembrane transporter activity", "id": "GO:0008509", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008509", "evidence": [ { "database": "UniProtKB", "id": "A0AAA9TV02", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TV02" } ], "pmid": "" }, { "name": "high-affinity L-glutamate transmembrane transporter activity", "id": "GO:0005314", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005314", "evidence": [ { "database": "UniProtKB", "id": "A0AAA9TV02", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TV02" } ], "pmid": "" }, { "name": "cysteine transmembrane transporter activity", "id": "GO:0033229", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0033229", "evidence": [ { "database": "UniProtKB", "id": "A0AAA9TV02", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TV02" } ], "pmid": "" }, { "name": "neutral L-amino acid transmembrane transporter activity", "id": "GO:0015175", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0015175", "evidence": [ { "database": "UniProtKB", "id": "A0AAA9TV02", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TV02" } ], "pmid": "" }, { "name": "glutamate:sodium symporter activity", "id": "GO:0015501", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0015501", "evidence": [ { "database": "UniProtKB", "id": "A0AAA9TV02", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TV02" } ], "pmid": "" }, { "name": "L-glutamate transmembrane transporter activity", "id": "GO:0005313", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005313", "evidence": [ { "database": "UniProtKB", "id": "A0AAA9TV02", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TV02" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 11, "go_terms": [ { "name": "transepithelial transport", "id": "GO:0070633", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0070633", "evidence": [ { "database": "UniProtKB", "id": "A0AAA9TV02", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TV02" } ], "pmid": "" }, { "name": "L-glutamate transmembrane transport", "id": "GO:0015813", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0015813", "evidence": [ { "database": "UniProtKB", "id": "A0AAA9TV02", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TV02" } ], "pmid": "" }, { "name": "transport across blood-brain barrier", "id": "GO:0150104", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0150104", "evidence": [ { "database": "UniProtKB", "id": "A0AAA9TV02", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TV02" } ], "pmid": "" }, { "name": "L-aspartate transmembrane transport", "id": "GO:0070778", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0070778", "evidence": [ { "database": "UniProtKB", "id": "A0AAA9TV02", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TV02" } ], "pmid": "" }, { "name": "glutathione biosynthetic process", "id": "GO:0006750", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006750", "evidence": [ { "database": "UniProtKB", "id": "A0AAA9TV02", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TV02" } ], "pmid": "" }, { "name": "protein homotrimerization", "id": "GO:0070207", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0070207", "evidence": [ { "database": "UniProtKB", "id": "A0AAA9TV02", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TV02" } ], "pmid": "" }, { "name": "D-aspartate import across plasma membrane", "id": "GO:0070779", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0070779", "evidence": [ { "database": "UniProtKB", "id": "A0AAA9TV02", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TV02" } ], "pmid": "" }, { "name": "L-glutamate import across plasma membrane", "id": "GO:0098712", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0098712", "evidence": [ { "database": "UniProtKB", "id": "A0AAA9TV02", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TV02" } ], "pmid": "" }, { "name": "L-aspartate import across plasma membrane", "id": "GO:0140009", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0140009", "evidence": [ { "database": "UniProtKB", "id": "A0AAA9TV02", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TV02" } ], "pmid": "" }, { "name": "cellular response to cocaine", "id": "GO:0071314", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0071314", "evidence": [ { "database": "UniProtKB", "id": "A0AAA9TV02", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TV02" } ], "pmid": "" }, { "name": "neurotransmitter reuptake", "id": "GO:0098810", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0098810", "evidence": [ { "database": "UniProtKB", "id": "A0AAA9TV02", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TV02" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 206, "end_pos": 208, "annotation": "n_glycosylation_sequon" }, { "start_pos": 216, "end_pos": 218, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [ { "id": "70699", "name": "", "equation": "K(+)(in) + L-glutamate(out) + 3 Na(+)(out) + H(+)(out) = K(+)(out) + L-glutamate(in) + 3 Na(+)(in) + H(+)(in)", "summary": "", "cellular_location": "", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [], "evidence": [ { "id": "70699", "database": "Rhea", "url": "https://www.rhea-db.org/rhea/70699" } ] }, { "id": "70851", "name": "", "equation": "K(+)(in) + L-aspartate(out) + 3 Na(+)(out) + H(+)(out) = K(+)(out) + L-aspartate(in) + 3 Na(+)(in) + H(+)(in)", "summary": "", "cellular_location": "", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [], "evidence": [ { "id": "70851", "database": "Rhea", "url": "https://www.rhea-db.org/rhea/70851" } ] }, { "id": "71379", "name": "", "equation": "D-aspartate(out) + K(+)(in) + 3 Na(+)(out) + H(+)(out) = D-aspartate(in) + K(+)(out) + 3 Na(+)(in) + H(+)(in)", "summary": "", "cellular_location": "", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [], "evidence": [ { "id": "71379", "database": "Rhea", "url": "https://www.rhea-db.org/rhea/71379" } ] } ], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" }, { "name": "homologset.oma", "label": "OMA Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 206, "end_pos": 208 }, { "start_pos": 216, "end_pos": 218 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ], "tool_support": { "graph_view": "yes" } }, { "uniprot_canonical_ac": "F1N4C1-1", "uniprot_ac": "F1N4C1", "uniprot_id": "F1N4C1_BOVIN", "mass": { "chemical_mass": 47278.0, "monoisotopic_mass": 47278.0 }, "refseq": { "ac": "NP_001179100", "name": "homeobox-containing protein 1", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001179100" }, "gene_names": [ { "name": "HMBOX1", "type": "recommended", "evidence": [ { "id": "F1N4C1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1N4C1" } ] }, { "name": "HMBOX1", "type": "synonym", "evidence": [ { "id": "NP_001179100", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001179100" } ] } ], "protein_names": [ { "name": "Homeobox-containing protein 1", "type": "recommended", "evidence": [ { "id": "F1N4C1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1N4C1/entry#names_and_taxonomy" } ] }, { "name": "homeobox-containing protein 1", "type": "synonym", "evidence": [ { "id": "NP_001179100", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001179100" } ] } ], "function": [ { "annotation": "Binds directly to 5'-TTAGGG-3' repeats in telomeric DNA. Associates with the telomerase complex at sites of active telomere processing and positively regulates telomere elongation. Important for TERT binding to chromatin, indicating a role in recruitment of the telomerase complex to telomeres. Also plays a role in the alternative lengthening of telomeres (ALT) pathway in telomerase-negative cells where it promotes formation and/or maintenance of ALT-associated promyelocytic leukemia bodies (APBs). Enhances formation of telomere C-circles in ALT cells, suggesting a possible role in telomere recombination. Might also be involved in the DNA damage response at telomeres.", "evidence": [ { "database": "UniProtKB", "id": "A0A3Q1LR21", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1LR21#function" }, { "database": "UniProtKB", "id": "ARBA00059255", "url": "https://www.uniprot.org/uniprotkb/ARBA00059255#function" }, { "database": "UniProtKB", "id": "A0A3Q1MMY0", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1MMY0#function" }, { "database": "UniProtKB", "id": "A0A3Q1MMZ7", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1MMZ7#function" }, { "database": "UniProtKB", "id": "F1N4C1", "url": "https://www.uniprot.org/uniprotkb/F1N4C1#function" }, { "database": "UniProtKB", "id": "A0A3Q1NM65", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1NM65#function" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Bos taurus", "taxid": 9913, "evidence": [ { "database": "UniProtKB", "id": "F1N4C1", "url": "https://www.uniprot.org/uniprotkb/F1N4C1" } ], "common_name": "Bovine", "glygen_name": "Bovine", "reference_species": "Bos taurus [9913]" } ], "gene": [ { "name": "HMBOX1", "url": "https://www.uniprot.org/uniprotkb/F1N4C1", "locus": { "chromosome": "8", "start_pos": 9648252, "end_pos": 9839295, "strand": "+", "evidence": [ { "database": "Ensembl Gene", "id": "ENSBTAG00000010819", "url": "https://www.ensembl.org/id/ENSBTAG00000010819" } ] } } ], "crossref": [ { "id": "F1N4C1", "url": "https://alphafold.ebi.ac.uk/entry/F1N4C1", "database": "AlphaFoldDB", "categories": [] }, { "id": "ENSBTAG00000010819", "url": "https://bgee.org/?page=gene&gene_id=ENSBTAG00000010819", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "cd00086", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd00086", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "cd00093", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd00093", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "539099", "url": "https://www.ncbi.nlm.nih.gov/gene/539099", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR001356", "url": "https://www.ebi.ac.uk/interpro/entry/IPR001356", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR001387", "url": "https://www.ebi.ac.uk/interpro/entry/IPR001387", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR006899", "url": "https://www.ebi.ac.uk/interpro/entry/IPR006899", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR009057", "url": "https://www.ebi.ac.uk/interpro/entry/IPR009057", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR010982", "url": "https://www.ebi.ac.uk/interpro/entry/IPR010982", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR040363", "url": "https://www.ebi.ac.uk/interpro/entry/IPR040363", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR044866", "url": "https://www.ebi.ac.uk/interpro/entry/IPR044866", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR044869", "url": "https://www.ebi.ac.uk/interpro/entry/IPR044869", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "bta:539099", "url": "https://www.genome.jp/dbget-bin/www_bget?bta:539099", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "XAAILES", "url": "https://omabrowser.org/oma/group/XAAILES/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "A0A3Q1LR21", "url": "https://www.orthodb.org/?gene=A0A3Q1LR21", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A3Q1NM65", "url": "https://www.orthodb.org/?gene=A0A3Q1NM65", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "F1N4C1", "url": "https://www.orthodb.org/?gene=F1N4C1", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR14618", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR14618", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR14618:SF0", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR14618:SF0", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00046", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00046", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF04814", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF04814", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "NP_001179100", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001179100", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A3Q1LR21", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1LR21", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A3Q1LR21-1", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1LR21-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A3Q1MMY0", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1MMY0", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A3Q1MMY0-1", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1MMY0-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A3Q1MMZ7", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1MMZ7", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A3Q1MMZ7-1", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1MMZ7-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A3Q1NM65", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1NM65", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A3Q1NM65-1", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1NM65-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "F1N4C1", "url": "https://www.uniprot.org/uniprotkb/F1N4C1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "F1N4C1-1", "url": "https://www.uniprot.org/uniprotkb/F1N4C1-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MLSSFPVVLLETMSHYTDEPRFTIEQIDLLQRLRRTGMTKHEILHALETLDRLDQEHSDKFGRRSSYGGSSYGNSTNNVPASSSTATASTQTQHSGMSPSPSNSYDTSPQPCTTNQNGRENNERLSTSNGKMSPTRYHANSMGQRSYSFEASEEDLDVDDKVEELMRRDSSVIKEEIKAFLANRRISQAVVAQVTGISQSRISHWLLQQGSDLSEQKKRAFYRWYQLEKTNPGATLSMRPAPIPIEDPEWRQTPPPVSATSGTFRLRRGSRFTWRKECLAVMESYFNENQYPDEAKREEIANACNAVIQKPGKKLSDLERVTSLKVYNWFANRRKEIKRRANIEAAILESHGIDVQSPGGHSNSDDVDGNDYSEQDDSTSHSDHQDPISLAVEMAAVNHTILALARQGANEIKTEALDDD", "length": 420, "header": "tr|F1N4C1-1|F1N4C1_BOVIN Isoform 1 of Homeobox-containing protein 1 OS=Bos taurus OX=9913 GN=HMBOX1 PE=4 SV=2 CANONICAL=F1N4C1-1" }, "isoforms": [ { "isoform_ac": "A0A3Q1LR21-1", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1LR21/entry", "sequence": { "sequence": "MLSSFPVVLLETMSHYTDEPRFTIEQIDLLQRLRRTGMTKHEILHALETLDRLDQEHSDKFGRRSSYGGSSYGNSTNNVPASSSTATASTQTQHSGMSPSPSNSYDTSPQPCTTNQNGRENNERLSTSNGKMSPTRYHANSMGQRSYSFEASEEDLDVDDKVEELMRRDSSVIKEEIKAFLANRRISQAVVAQVTGISQSRISHWLLQQGSDLSEQKKRAFYRWYQLEKTNPGATLSMRPAPIPIEDPEWRQTPPPVSATSGTFRLRRGSRFTWRKECLAVMESYFNENQYPDEAKREEIANACNAVIQKPGKKLSDLERVTSLKVYNWFANRRKEIKRRANIEAAILESHGIDVQSPGGHSNSDDVDGNDYSEQDTWQAPAGTHLLFPGQCTLLGQLVNKSPPCSPVHRPAA", "length": 413, "header": "tr|A0A3Q1LR21-1|F1N4C1_BOVIN Computationally mapped isoform of Homeobox-containing protein 1 OS=Bos taurus OX=9913 GN=HMBOX1 PE=4 SV=2 CANONICAL=F1N4C1-1" }, "locus": { "chromosome": "8", "start_pos": 9761296, "end_pos": 9651569, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000081600.2", "url": "https://www.ensembl.org/id/ENSBTAT00000081600.2" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000059561.2", "url": "https://www.ensembl.org/id/ENSBTAP00000059561.2" } ] } }, { "isoform_ac": "A0A3Q1MMY0-1", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1MMY0/entry", "sequence": { "sequence": "MLSSFPVVLLETMSHYTDEPRFTIEQIDLLQRLRRTGMTKHEILHALETLDRLDQEHSDKFGRRSSYGGSSYGNSTNNVPASSSTATASTQTQHSGMSPSPSNSYDTSPQPCTTNQNGRENNERLSTSNGKMSPTRYHANSMGQRSYSFEASEEDLDVDDKVEELMRRDSSVIKEEIKAFLANRRISQAVVAQVTGISQSRISHWLLQQGSDLSEQKKRAFYRWYQLEKTNPGATLSMRPAPIPIEDPEWRQTPPPVSATSGTFRLRRGSRFTWRKECLAVMESYFNENQYPDEAKREEIANACNAVIQKPGKKLSDLERVTSLKVYNWFANRRKEIKRRANIEAAILESHGIDVQSPGGHSNSDDVDGNDYSEQNSKYQTVNLR", "length": 385, "header": "tr|A0A3Q1MMY0-1|F1N4C1_BOVIN Computationally mapped isoform of Homeobox-containing protein 1 OS=Bos taurus OX=9913 GN=HMBOX1 PE=4 SV=1 CANONICAL=F1N4C1-1" }, "locus": { "chromosome": "8", "start_pos": 9761296, "end_pos": 9648967, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000071418.2", "url": "https://www.ensembl.org/id/ENSBTAT00000071418.2" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000073209.2", "url": "https://www.ensembl.org/id/ENSBTAP00000073209.2" } ] } }, { "isoform_ac": "A0A3Q1MMZ7-1", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1MMZ7/entry", "sequence": { "sequence": "MLSSFPVVLLETMSHYTDEPRFTIEQIDLLQRLRRTGMTKHEILHALETLDRLDQEHSDKFGRRSSYGGSSYGNSTNNVPASSSTATASTQTQHSGMSPSPSNSYDTSPQPCTTNQNGRENNERLSTSNGKMSPTRYHANSMGQRSYSFEASEEDLDVDDKVEELMRRDSSVIKEEIKAFLANRRISQAVVAQVTGISQSRISHWLLQQGSDLSEQKKRAFYRWYQLEKTNPGATLSMRPAPIPIEDPEWRQTPPPVSATSGTFRLRRGSRFTWRKECLAVMESYFNENQYPDEAKREEIANACNAVIQKPGKKLSDLERVTSLKVYNWFANRRKEIKRRANIEAAILESHGIDVQSPGGHSNSDDVDGNDYSEQAPAGTHLLFPGQCTLLGQLVNKSPPCSPVHRPAA", "length": 409, "header": "tr|A0A3Q1MMZ7-1|F1N4C1_BOVIN Computationally mapped isoform of Homeobox-containing protein 1 OS=Bos taurus OX=9913 GN=HMBOX1 PE=4 SV=2 CANONICAL=F1N4C1-1" }, "locus": { "chromosome": "8", "start_pos": 9761296, "end_pos": 9651569, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000066390.3", "url": "https://www.ensembl.org/id/ENSBTAT00000066390.3" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000072579.3", "url": "https://www.ensembl.org/id/ENSBTAP00000072579.3" } ] } }, { "isoform_ac": "A0A3Q1NM65-1", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1NM65/entry", "sequence": { "sequence": "MLSSFPVVLLETMSHYTDEPRFTIEQIDLLQRLRRTGMTKHEILHALETLDRLDQEHSDKFGRRSSYGGSSYGNSTNNVPASSSTATASTQTQHSGMSPSPSNSYDTSPQPCTTNQNGRENNERLSTSNGKMSPTRYHANSMGQRSYSFEASEEDLDVDDKVEELMRRDSSVIKEEIKAFLANRRISQAVVAQVTGISQSRISHWLLQQGSDLSEQKKRAFYRWYQLEKTNPGATLSMRPAPIPIEDPEWRQTPPPVSATSGTFRLRRGSRFTWRKECLAVMESYFNENQYPDEAKREEIANACNAVIQKPGKKLSDLERVTSLKVYNWFANRRKEIKRRANIEAAILESHGIDVQSPGGHSNSDDVDGNDYSEQDTWQVRNGEEEEGRSSEGGREAEKDDSTSHSDHQDPISLAVEMAAVNHTILALARQGANEIKTEALDDD", "length": 444, "header": "tr|A0A3Q1NM65-1|F1N4C1_BOVIN Computationally mapped isoform of Homeobox-containing protein 1 OS=Bos taurus OX=9913 GN=HMBOX1 PE=4 SV=2 CANONICAL=F1N4C1-1" }, "locus": { "chromosome": "8", "start_pos": 9761296, "end_pos": 9650390, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000084663.2", "url": "https://www.ensembl.org/id/ENSBTAT00000084663.2" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000073632.2", "url": "https://www.ensembl.org/id/ENSBTAP00000073632.2" } ] } }, { "isoform_ac": "F1N4C1-1", "url": "https://www.uniprot.org/uniprotkb/F1N4C1/entry", "sequence": { "sequence": "MLSSFPVVLLETMSHYTDEPRFTIEQIDLLQRLRRTGMTKHEILHALETLDRLDQEHSDKFGRRSSYGGSSYGNSTNNVPASSSTATASTQTQHSGMSPSPSNSYDTSPQPCTTNQNGRENNERLSTSNGKMSPTRYHANSMGQRSYSFEASEEDLDVDDKVEELMRRDSSVIKEEIKAFLANRRISQAVVAQVTGISQSRISHWLLQQGSDLSEQKKRAFYRWYQLEKTNPGATLSMRPAPIPIEDPEWRQTPPPVSATSGTFRLRRGSRFTWRKECLAVMESYFNENQYPDEAKREEIANACNAVIQKPGKKLSDLERVTSLKVYNWFANRRKEIKRRANIEAAILESHGIDVQSPGGHSNSDDVDGNDYSEQDDSTSHSDHQDPISLAVEMAAVNHTILALARQGANEIKTEALDDD", "length": 420, "header": "tr|F1N4C1-1|F1N4C1_BOVIN Isoform 1 of Homeobox-containing protein 1 OS=Bos taurus OX=9913 GN=HMBOX1 PE=4 SV=2 CANONICAL=F1N4C1-1" }, "locus": { "chromosome": "8", "start_pos": 9761296, "end_pos": 9650390, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000014352.6", "url": "https://www.ensembl.org/id/ENSBTAT00000014352.6" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000014352.5", "url": "https://www.ensembl.org/id/ENSBTAP00000014352.5" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [ { "id": "bta:539099", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?bta:539099", "resource": "KEGG Pathway" } ], "orthologs": [ { "uniprot_canonical_ac": "A0A8V0YGB9-1", "protein_name": "Homeobox-containing protein 1", "gene_name": "HMBOX1", "tax_id": 9031, "organism": "Gallus gallus", "sequence": { "sequence": "MLRTFPVVLLETMSHYTDEPRFTIEQIDLLQRLRRTGMTRHEILHALETLDRLDQEHSDKFGRRSSYGGGSYSNSTNNVPASSSTATASTQTQHSGMSPSPSNSYDTSPQPCTTNQNGRESNERLSAFNGKMSPTRYPLANSLAQRSYSFEASEEDLDIDDKVEELMRRDSSVIKEEIKAFLANRRISQAVVAQVTGISQSRISHWLLQQGSDLSEQKKRAFYRWYQLEKTNPGATLSMRPAPIPIEEPEWRQTPPPVTATSGTFRLRRGSRFTWRKECLAVMESYFNENQYPDEAKREEIANACNAVIQKPGKKLSDLERVTSLKVYNWFANRRKEIKRRANIAILESHGIDVQSPGGHSNSDDVDGNDYSEQDDSTSHSDHQDPISLAVEMAAVNHTILALARQGANEIKTEALDDD", "length": 419 }, "evidence": [ { "id": "F1N4C1", "url": "https://omabrowser.org/oma/group/F1N4C1/", "database": "OMA" } ], "glygen_name": "Chicken", "common_name": "Chicken" }, { "uniprot_canonical_ac": "F1RJQ0-1", "protein_name": "Homeobox-containing protein 1", "gene_name": "HMBOX1", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MLSSFPVVLLETMSHYTDEPRFTIEQIDLLQRLRRTGMTKHEILHALETLDRLDQEHSDKFGRRSSYGGGSYGNNTNNVPASSSTATASTQTQHSGMSPSPSNSYDTSPQPCTTNQNGRENNERLSTSNGKMSPTRYHANSMGQRSYSFEASEEDLDVDDKVEELMRRDSSVIKEEIKAFLANRRISQAVVAQVTGISQSRISHWLLQQGSDLSEQKKRAFYRWYQLEKTNPGATLSMRPAPIPIEDPEWRQTPPPVSATSGTFRLRRGSRFTWRKECLAVMESYFNENQYPDEAKREEIANACNAVIQKPGKKLSDLERVTSLKVYNWFANRRKEIKRRANIEAAILESHGIDVQSPGGHSNSDDVDGNDYSEQDDSTSHSDHQDPISLAVEMAAVNHTILALARQGANEIKTEALDDD", "length": 420 }, "evidence": [ { "id": "F1N4C1", "url": "https://omabrowser.org/oma/group/F1N4C1/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "Q6NT76-1", "protein_name": "Homeobox-containing protein 1", "gene_name": "HMBOX1", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MLSSFPVVLLETMSHYTDEPRFTIEQIDLLQRLRRTGMTKHEILHALETLDRLDQEHSDKFGRRSSYGGSSYGNSTNNVPASSSTATASTQTQHSGMSPSPSNSYDTSPQPCTTNQNGRENNERLSTSNGKMSPTRYHANSMGQRSYSFEASEEDLDVDDKVEELMRRDSSVIKEEIKAFLANRRISQAVVAQVTGISQSRISHWLLQQGSDLSEQKKRAFYRWYQLEKTNPGATLSMRPAPIPIEDPEWRQTPPPVSATSGTFRLRRGSRFTWRKECLAVMESYFNENQYPDEAKREEIANACNAVIQKPGKKLSDLERVTSLKVYNWFANRRKEIKRRANIEAAILESHGIDVQSPGGHSNSDDVDGNDYSEQDDSTSHSDHQDPISLAVEMAAVNHTILALARQGANEIKTEALDDD", "length": 420 }, "evidence": [ { "id": "F1N4C1", "url": "https://omabrowser.org/oma/group/F1N4C1/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" } ], "go_annotation": { "categories": [ { "name": "Biological Process", "total": 5, "go_terms": [ { "name": "negative regulation of transcription by RNA polymerase II", "id": "GO:0000122", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000122", "evidence": [ { "database": "UniProtKB", "id": "F1N4C1", "url": "https://www.uniprot.org/uniprotkb/F1N4C1" } ], "pmid": "" }, { "name": "DNA-templated transcription", "id": "GO:0006351", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006351", "evidence": [ { "database": "UniProtKB", "id": "F1N4C1", "url": "https://www.uniprot.org/uniprotkb/F1N4C1" } ], "pmid": "" }, { "name": "positive regulation of DNA-templated transcription", "id": "GO:0045893", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0045893", "evidence": [ { "database": "UniProtKB", "id": "F1N4C1", "url": "https://www.uniprot.org/uniprotkb/F1N4C1" } ], "pmid": "" }, { "name": "telomere-telomerase complex assembly", "id": "GO:1905324", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:1905324", "evidence": [ { "database": "UniProtKB", "id": "F1N4C1", "url": "https://www.uniprot.org/uniprotkb/F1N4C1" } ], "pmid": "" }, { "name": "telomere maintenance via telomerase", "id": "GO:0007004", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007004", "evidence": [ { "database": "UniProtKB", "id": "F1N4C1", "url": "https://www.uniprot.org/uniprotkb/F1N4C1" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 6, "go_terms": [ { "name": "cytosol", "id": "GO:0005829", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005829", "evidence": [ { "database": "UniProtKB", "id": "F1N4C1", "url": "https://www.uniprot.org/uniprotkb/F1N4C1" } ], "pmid": "" }, { "name": "PML body", "id": "GO:0016605", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016605", "evidence": [ { "database": "UniProtKB", "id": "F1N4C1", "url": "https://www.uniprot.org/uniprotkb/F1N4C1" } ], "pmid": "" }, { "name": "Cajal body", "id": "GO:0015030", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0015030", "evidence": [ { "database": "UniProtKB", "id": "F1N4C1", "url": "https://www.uniprot.org/uniprotkb/F1N4C1" } ], "pmid": "" }, { "name": "chromosome, telomeric region", "id": "GO:0000781", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000781", "evidence": [ { "database": "UniProtKB", "id": "F1N4C1", "url": "https://www.uniprot.org/uniprotkb/F1N4C1" } ], "pmid": "" }, { "name": "cytoplasm", "id": "GO:0005737", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005737", "evidence": [ { "database": "UniProtKB", "id": "F1N4C1", "url": "https://www.uniprot.org/uniprotkb/F1N4C1" } ], "pmid": "" }, { "name": "nucleus", "id": "GO:0005634", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005634", "evidence": [ { "database": "UniProtKB", "id": "F1N4C1", "url": "https://www.uniprot.org/uniprotkb/F1N4C1" } ], "pmid": "" } ] }, { "name": "Molecular Function", "total": 4, "go_terms": [ { "name": "identical protein binding", "id": "GO:0042802", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0042802", "evidence": [ { "database": "UniProtKB", "id": "F1N4C1", "url": "https://www.uniprot.org/uniprotkb/F1N4C1" } ], "pmid": "" }, { "name": "protein-containing complex binding", "id": "GO:0044877", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0044877", "evidence": [ { "database": "UniProtKB", "id": "F1N4C1", "url": "https://www.uniprot.org/uniprotkb/F1N4C1" } ], "pmid": "" }, { "name": "double-stranded telomeric DNA binding", "id": "GO:0003691", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003691", "evidence": [ { "database": "UniProtKB", "id": "F1N4C1", "url": "https://www.uniprot.org/uniprotkb/F1N4C1" } ], "pmid": "" }, { "name": "sequence-specific double-stranded DNA binding", "id": "GO:1990837", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:1990837", "evidence": [ { "database": "UniProtKB", "id": "F1N4C1", "url": "https://www.uniprot.org/uniprotkb/F1N4C1" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 398, "end_pos": 400, "annotation": "n_glycosylation_sequon" }, { "start_pos": 74, "end_pos": 76, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [ { "pdb_id": "AF-F1N4C1-F1", "pdb_chain": "global", "start_pos": 1, "end_pos": 420, "overlap": "1.0", "method": "AlphaFold", "type": "alphafold", "resolution": -1.0, "url": "https://data.glygen.org/ln2downloads/pdb/current/AF-F1N4C1-F1.pdb", "url_external": "https://alphafold.ebi.ac.uk/entry/F1N4C1" } ], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "F1N4C1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1N4C1" }, { "id": "PRU00108", "database": "PROSITE", "url": "https://prosite.expasy.org/PRU00108" } ], "ann_type": "Nucleotide_Binding_Annotation", "uniprotkb_annotation": "Homeobox", "eco_id": "ECO_0000256", "start_pos": 267, "end_pos": 341, "start_aa": "Arg", "end_aa": "Ala", "glycosite_overlap": [] } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" }, { "name": "homologset.oma", "label": "OMA Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 398, "end_pos": 400 }, { "start_pos": 74, "end_pos": 76 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { 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"table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ], "tool_support": { "graph_view": "yes" } }, { "uniprot_canonical_ac": "F1N6Y6-1", "uniprot_ac": "F1N6Y6", "uniprot_id": "F1N6Y6_BOVIN", "mass": { "chemical_mass": 47269.0, "monoisotopic_mass": 47269.0 }, "refseq": { "ac": "NP_001192308", "name": "tubulin epsilon and delta complex protein 2", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001192308" }, "gene_names": [ { "name": "CCNF", "type": "recommended", "evidence": [ { "id": "F1N6Y6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1N6Y6" } ] }, { "name": "TEDC2", "type": "recommended", "evidence": [ { "id": "F1N6Y6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1N6Y6" } ] }, { "name": "C25H16orf59", "type": "synonym", "evidence": [ { "id": "NP_001192308", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001192308" } ] }, { "name": "TEDC2", "type": "synonym", "evidence": [ { "id": "NP_001192308", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001192308" } ] } ], "protein_names": [ { "name": "Tubulin epsilon and delta complex 2", "type": "synonym", "evidence": [ { "id": "F1N6Y6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1N6Y6/entry#names_and_taxonomy" } ] }, { "name": "tubulin epsilon and delta complex protein 2", "type": "synonym", "evidence": [ { "id": "NP_001192308", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001192308" } ] }, { "name": "uncharacterized protein C16orf59 homolog", "type": "synonym", "evidence": [ { "id": "NP_001192308", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001192308" } ] } ], "function": [], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Bos taurus", "taxid": 9913, "evidence": [ { "database": "UniProtKB", "id": "F1N6Y6", "url": "https://www.uniprot.org/uniprotkb/F1N6Y6" } ], "common_name": "Bovine", "glygen_name": "Bovine", "reference_species": "Bos taurus [9913]" } ], "gene": [ { "name": "TEDC2", "url": "https://www.uniprot.org/uniprotkb/F1N6Y6", "locus": { "chromosome": "25", "start_pos": 1970947, "end_pos": 1966625, "strand": "-", "evidence": [ { "database": "Ensembl Gene", "id": "ENSBTAG00000024884", "url": "https://www.ensembl.org/id/ENSBTAG00000024884" } ] } } ], "crossref": [ { "id": "F1N6Y6", "url": "https://alphafold.ebi.ac.uk/entry/F1N6Y6", "database": "AlphaFoldDB", "categories": [] }, { "id": "ENSBTAG00000024884", "url": "https://bgee.org/?page=gene&gene_id=ENSBTAG00000024884", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "cd20521", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd20521", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "cd22082", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd22082", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "616898", "url": "https://www.ncbi.nlm.nih.gov/gene/616898", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR001810", "url": "https://www.ebi.ac.uk/interpro/entry/IPR001810", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR004367", "url": "https://www.ebi.ac.uk/interpro/entry/IPR004367", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR006671", "url": "https://www.ebi.ac.uk/interpro/entry/IPR006671", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR011990", "url": "https://www.ebi.ac.uk/interpro/entry/IPR011990", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR013763", "url": "https://www.ebi.ac.uk/interpro/entry/IPR013763", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR031518", "url": "https://www.ebi.ac.uk/interpro/entry/IPR031518", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR036047", "url": "https://www.ebi.ac.uk/interpro/entry/IPR036047", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR036915", "url": "https://www.ebi.ac.uk/interpro/entry/IPR036915", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR048258", "url": "https://www.ebi.ac.uk/interpro/entry/IPR048258", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "bta:616898", "url": "https://www.genome.jp/dbget-bin/www_bget?bta:616898", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "HQAKKSC", "url": "https://omabrowser.org/oma/group/HQAKKSC/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "A0A452DK24", "url": "https://www.orthodb.org/?gene=A0A452DK24", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "F1N6Y6", "url": "https://www.orthodb.org/?gene=F1N6Y6", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR14870", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR14870", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR14870:SF1", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR14870:SF1", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00134", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00134", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF00646", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00646", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF02984", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF02984", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF15764", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF15764", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "NP_001192308", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001192308", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A452DK24", "url": "https://www.uniprot.org/uniprotkb/A0A452DK24", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A452DK24-1", "url": "https://www.uniprot.org/uniprotkb/A0A452DK24-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0ABI0NJ29", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NJ29", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0ABI0NJ29-1", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NJ29-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "F1N6Y6", "url": "https://www.uniprot.org/uniprotkb/F1N6Y6", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "F1N6Y6-1", "url": "https://www.uniprot.org/uniprotkb/F1N6Y6-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MLPAECSRRLVAELRDALDSCAERQRQLEQSLRVSRRLLRVWEPAETPAPEPTPGSEINKEAPSSACPPSPQDLKELELLTQALEKAVRVRKGLSKAGEGVKARSLKSGSASTATKASAPPSTSRCTGSRAPETKPPRGVHHPWVPAKDLPGHRLLLVGDGAHMGQGAGANKPEAGLRDQQIVPQAASQVPEAFTLKDKGALLRLPEAFRKAASRNASLWAQLSSMQTRDSVDAAAATAKTQFLQKMQTAAGLPSSMLSAAEVGRLQKACSMLRLRMREELTADPKDWTQEYRSLLTLEGLQALAGQCLHRLQELQELRSAVVEQPQGPWPEGPPRAALPCGGGADPVWSPQLLLYSSTQELQTLAALRLRVAMLDQQVHLEKVLMAELLPLLSEQEPLGRPWLALCRAAHCLLCEGGQRFLTVLQDEPADRLSPP", "length": 436, "header": "tr|F1N6Y6-1|F1N6Y6_BOVIN Isoform 1 of Tubulin epsilon and delta complex 2 OS=Bos taurus OX=9913 GN=TEDC2 PE=4 SV=3 CANONICAL=F1N6Y6-1" }, "isoforms": [ { "isoform_ac": "A0A452DK24-1", "url": "https://www.uniprot.org/uniprotkb/A0A452DK24/entry", "sequence": { "sequence": "MGSGGVIHCRCAKCFCYPSKRRIRRRPRNLTILNLPEDALFHILKWLSVGDILAVRAVHSHLKYLVDNHASVWACASFQELWPSPGNLKLFERAAEKGNFEAAVKLGIAYLYNEGLSVSDEARAEVNGLRASRYFSLAERLNVGAAPFIWLFIRPPWSVSGSCCKAVVHESLRAECQLQKTHRASILHCLGRVLSLFEDEEKQKQARKLFEESANQGCLTSSYLLWESDRRMDMLDPGRCLHSFRKLRDFAAKGCWEAQLSLAKACAHGHQLGLEAKASSEIVCQLFQASHAVNKQRVFSVQKGLNDTMRYILIDWLVEVATMKDFSSLCLHLTVECVDRYLRRRLVPRYRLQLLGIACMVICTRFISKEILTIREAVWLTDNTYKYEDLVRMMGEVVSALDGKIRVPTVVDYKDVLLTLVPMAPRTQHLCSFLCELSLLHTSLAAYAPAHLAAAALLLARLTHGQTQPWTTQLWDLTGFSCEDLIPCVLSLHQKCFHDDAPKDYRQVSLTAVKQRFEDKRYEEISLEEVLSYGQLCAALGVKQESLEPAPFLSAGDIHAFLSSPSARRTKRKRENSLQEDRGSFVTTPTAELSSQEETLLGSFLDWSLDYCSGYEGDQESEGEKEGDVTAPSGVLDVTVVYLSPEEHCCQESSDEEACPEEACGAQDTQALVPGHQALRTPGPEPPLCSRWGLGKDVTTSGYSSVNSASPTDSGRTSGGPPRSTSELPTGSSLNTQPCHHHARKSCLQCRPPSPPESCAPQQQVKRKNLSAHSEEEEEDMNLGFLKLLVAELRDALDSCAERQRQLEQSLRVSRRLLRVWEPAETPAPEPTPGSEINKEAPSSACPPSPQDLKELELLTQALEKAVRVRKGLSKAGEGVKARSLKSGSASTATKASAPPSTSRCTGSRAPETKPPRGVHHPWVPAKDLPGHRLLLVGDGAHMGQGAGANKPEAGLRDQQIVPQAASQVPEAFTLKDKGALLRLPEAFRKAASRNASLWAQLSSMQTRDSVDAAAATAKTQFLQKMQTAAGLPSSMLSAAEVGRLQKACSMLRLRMREELTADPKDWTQEYRSLLTLEGLQALAGQCLHRLQELQELRSAVVEQPQGPWPEGPPRAALPCGGGADPVWSPQLLLYSSTQELQTLAALRLRVAMLDQQVHLEKVLMAELLPLLSEQEPLGRPWLALCRAAHCLLCEGGQRFLTVLQDEPADRLSPP", "length": 1215, "header": "tr|A0A452DK24-1|F1N6Y6_BOVIN Computationally mapped isoform of Tubulin epsilon and delta complex 2 OS=Bos taurus OX=9913 GN=TEDC2 PE=4 SV=1 CANONICAL=F1N6Y6-1" }, "locus": { "chromosome": "25", "start_pos": 1963975, "end_pos": 1947732, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000034643.5", "url": "https://www.ensembl.org/id/ENSBTAT00000034643.5" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000034530.5", "url": "https://www.ensembl.org/id/ENSBTAP00000034530.5" } ] } }, { "isoform_ac": "A0ABI0NJ29-1", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NJ29/entry", "sequence": { "sequence": "MLPAECSRRLVAELRDALDSCAERQRQLEQSLRVSRRLLRVWEPAETPAPEPTPGSEINKEAPSSACPPSPQDLKELELLTQALEKAVRVRKGLSKAGEGVKARSLKSGSASTATKASAPPSTSRCTGSRAPETKPPRGVHHPWVPAKDLPGHRLLLVGDGAHMGQGAGANKPEAGLRDQQIVPQAASQVPEAFTLKDKGALLRLPEAFRKAASRNASLWAQLSSMQTRDSVDAAAATAKTQFLQKMQTAAGLPSSMLSAAEVGRLQKACSMLRLRMREELTAAVVEQPQGPWPEGPPRAALPCGGGADPVWSPQLLLYSSTQELQTLAALRLRVAMLDQQVHLEKVLMAELLPLLSEQEPLGRPWLALCRAAHCLLCEGGQRFLTVLQDEPADRLSPP", "length": 399, "header": "tr|A0ABI0NJ29-1|A0ABI0NJ29_BOVIN Computationally mapped isoform of Tubulin epsilon and delta complex 2 OS=Bos taurus OX=9913 GN=TEDC2 PE=4 SV=1 CANONICAL=F1N6Y6-1" }, "locus": { "chromosome": "25", "start_pos": 1970551, "end_pos": 1966676, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000144552.1", "url": "https://www.ensembl.org/id/ENSBTAT00000144552.1" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000104327.1", "url": "https://www.ensembl.org/id/ENSBTAP00000104327.1" } ] } }, { "isoform_ac": "F1N6Y6-1", "url": "https://www.uniprot.org/uniprotkb/F1N6Y6/entry", "sequence": { "sequence": "MLPAECSRRLVAELRDALDSCAERQRQLEQSLRVSRRLLRVWEPAETPAPEPTPGSEINKEAPSSACPPSPQDLKELELLTQALEKAVRVRKGLSKAGEGVKARSLKSGSASTATKASAPPSTSRCTGSRAPETKPPRGVHHPWVPAKDLPGHRLLLVGDGAHMGQGAGANKPEAGLRDQQIVPQAASQVPEAFTLKDKGALLRLPEAFRKAASRNASLWAQLSSMQTRDSVDAAAATAKTQFLQKMQTAAGLPSSMLSAAEVGRLQKACSMLRLRMREELTADPKDWTQEYRSLLTLEGLQALAGQCLHRLQELQELRSAVVEQPQGPWPEGPPRAALPCGGGADPVWSPQLLLYSSTQELQTLAALRLRVAMLDQQVHLEKVLMAELLPLLSEQEPLGRPWLALCRAAHCLLCEGGQRFLTVLQDEPADRLSPP", "length": 436, "header": "tr|F1N6Y6-1|F1N6Y6_BOVIN Isoform 1 of Tubulin epsilon and delta complex 2 OS=Bos taurus OX=9913 GN=TEDC2 PE=4 SV=3 CANONICAL=F1N6Y6-1" }, "locus": { "chromosome": "25", "start_pos": 1970551, "end_pos": 1966676, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000034642.6", "url": "https://www.ensembl.org/id/ENSBTAT00000034642.6" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000034529.5", "url": "https://www.ensembl.org/id/ENSBTAP00000034529.5" } ] } } ], "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "other", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 53, "start_aa": "Thr", "end_pos": 53, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr53", "evidence": [ { "id": "", "database": "GlyGen", "url": "https://data.glygen.org/" } ], "filter_code": "000000000000000010000.00000000001000.0.01000" } ], "phosphorylation": [], "glycation": [], "keywords": [ "glycoprotein", "glycoprotein_predicted" ], "publication": [], "pathway": [ { "id": "bta:616898", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?bta:616898", "resource": "KEGG Pathway" } ], "orthologs": [ { "uniprot_canonical_ac": "P41002-1", "protein_name": "Cyclin-F", "gene_name": "CCNF", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MGSGGVVHCRCAKCFCYPTKRRIRRRPRNLTILSLPEDVLFHILKWLSVEDILAVRAVHSQLKDLVDNHASVWACASFQELWPSPGNLKLFERAAEKGNFEAAVKLGIAYLYNEGLSVSDEARAEVNGLKASRFFSLAERLNVGAAPFIWLFIRPPWSVSGSCCKAVVHESLRAECQLQRTHKASILHCLGRVLSLFEDEEKQQQAHDLFEEAAHQGCLTSSYLLWESDRRTDVSDPGRCLHSFRKLRDYAAKGCWEAQLSLAKACANANQLGLEVRASSEIVCQLFQASQAVSKQQVFSVQKGLNDTMRYILIDWLVEVATMKDFTSLCLHLTVECVDRYLRRRLVPRYRLQLLGIACMVICTRFISKEILTIREAVWLTDNTYKYEDLVRMMGEIVSALEGKIRVPTVVDYKEVLLTLVPVELRTQHLCSFLCELSLLHTSLSAYAPARLAAAALLLARLTHGQTQPWTTQLWDLTGFSYEDLIPCVLSLHKKCFHDDAPKDYRQVSLTAVKQRFEDKRYGEISQEEVLSYSQLCAALGVTQDSPDPPTFLSTGEIHAFLSSPSGRRTKRKRENSLQEDRGSFVTTPTAELSSQEETLLGSFLDWSLDCCSGYEGDQESEGEKEGDVTAPSGILDVTVVYLNPEQHCCQESSDEEACPEDKGPQDPQALALDTQIPATPGPKPLVRTSREPGKDVTTSGYSSVSTASPTSSVDGGLGALPQPTSVLSLDSDSHTQPCHHQARKSCLQCRPPSPPESSVPQQQVKRINLCIHSEEEDMNLGLVRL", "length": 786 }, "evidence": [ { "id": "F1N6Y6", "url": "https://omabrowser.org/oma/group/F1N6Y6/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "P51944-1", "protein_name": "Cyclin-F", "gene_name": "Ccnf", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MGSGGVIHCRCAKCFCYPTKRRIKRRPRNLTILSLPEDVLFHILKWLSVGDILAVRAVHSHLKYLVDNHASVWASASFQELWPSPQNLKLFERAAEKGNFEAAVKLGIAYLYNEGLSVSDEACAEVNGLKASRFFSMAERLNTGSEPFIWLFIRPPWSVSGSCCKAVVHDSLRAECQLQRSHKASILHCLGRVLNLFEDEEKRKQARSLLEESSRQGCLISSYLLWESDRKVDMSDPGRCLHSFRKLRDYAAKGCWEAQLALAKACAGGSQLGLEGKACSESVCQLFQASQAVNKQQIFSVQKGLSDTMRYILIDWLVEVATMKDFTSLCLHLTVECVDRYLRRRLVPRYKLQLLGIACMVICTRFISKEILTIREAVWLTDNTYKYEDLVRVMGEIISALEGKIRIPTVVDYKEVLLTLVPVAPRTQHLCSFLCELTLLHTSLSIYAPARLASAALLLARLMHGQTQPWTTHLWDLTGFSYSDLVPCVLSLHKKCFHDDAPKDYRQVSLTAVKQRFEDKCYEEISREEVLSYADLCSTIGVKQESPEPPSFPSSGEIHTFLSSPSGRRSKRKRENSLQEDRGSFVTTPTAELSNQEETLLGSLLDWSLECCSGYEGDQESEGEKEGDVTAPSRLLDVTVVYLNPEEHCCQESSDEEAWPEDKIHPAPGTQAPPASAPRPLLCNRGDRAKDITTSGYSSVSSSSPISSLDGGMGGSPQSTSVLSVGSHSSTKPCHHQAKKSCLQCRPPNSPESGVHQQPVKRQNLSVHSDKDMHLAS", "length": 777 }, "evidence": [ { "id": "F1N6Y6", "url": "https://omabrowser.org/oma/group/F1N6Y6/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q6NYX6-1", "protein_name": "Cyclin-F", "gene_name": "ccnf", "tax_id": 7955, "organism": "Danio rerio", "sequence": { "sequence": "MKAGALHCRCAKCFSLPVRKRVRKRASAVSLLSLPEELLVFVLQCLSAEDLLSVRAVHSHLCDIIDTNASIWARVSFKDRWPAPDTVWLFERAAEKGNFEAAVKLGIAYLYNEGPLLSEEGRADLCGRMASRYLSLSESLRSPQAEPFIWLFIRPPWSVSGSCCKAVVFDRLQAECQTSPGRKGTLLYCLARVLQLFDDEEKRDEAELMLKESSRCGSLQSSYLLWAISRASSTADPGRYLQCMRTLRDYAARGCWEAQLAFVKSCGSANPLGLEPRACSELVSQFFQTGPSALRYQPHLQGQDITTKRYILVDWLVEVTTTKDFSSQVLHVTISCVDRYLHLRSVPKAQLQLLGIACMVICTRFISKEILTIREAVWLTDNTYQYEDLVHMMGEVISVLDGKIRTPTVLDYGEVLLSLLPVERRTAHLFSYICELSLLCSPATVPGPARLASAILLLTRALHNYVPVWPVQLEENTGFSKQDLVSCALTLYIKCFGQDVPKDYRHVSLTGVKQRFEDDSYQQISKDTVMGFKELCHVLEVPEVEPQVEVSSTSGQITEMHTFLSSPTSSSKRRRADSMQAHRGAFVATPTAELSNQEETLLGDFLDWSLDTSCSGYEGDRESEGEKDGEISTMEVQMELPLDCADRQTHCCLLSSDDTSLCEEDEQEPPTGGSKPWTRHLSSSSTSSSSSSCGFCTDRHSSGYSSIQSFPSPTGSSALVSPQNPPGVPSQRIRRQVKRKNTAAHSAGEAEQEDDAANLAFLSF", "length": 764 }, "evidence": [ { "id": "F1N6Y6", "url": "https://omabrowser.org/oma/group/F1N6Y6/", "database": "OMA" } ], "glygen_name": "Zebrafish", "common_name": "Zebrafish" }, { "uniprot_canonical_ac": "Q8K4F8-1", "protein_name": "Cyclin-F", "gene_name": "Ccnf", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MGSGGVIHCRCAKCFCYPTKRRIKRRPRNLTILSLPEDVLFHILKWLSVGDILAVRAVHSHLKYLVDNHASVWASASFQELWPSPQNLKLFERAAEKGNFEAAVKLGIAYLYNEGLSVSDEACAEVNGLKASRFFSMAERLNTGSDPFIWLFIRPPWSVSGSCCKAVVHDSLRAECQLQRSHKASILHCLGRVLNLFEDEEKRKQAHNLFEESAHQGCLASSYLLWESDRKVDMSDPGRCLHSFRKLRDYAAKGCWEAQLALAKACAGGSQLGLEGKACSESVCQLFQASQAVNKQQIFSVQKGLSDTMRYILIDWLVEVATMKDFTSLCLHLTVECVDRYLRRRLVPRYKLQLLGIACMVICTRFISKEILTIREAVWLTDNTYKYEDLVRVMGEIISALEGKIRIPTVVDYKEVLLTLVPVAPRTQHLCSFLCELTLLHTSLSVYAPARLASAALLLARLMHGHTQPWTTQLWDLTGFSYSDLTPCVLSLHKKCFHDDAPKDYRQVSLTAVKQRFEDKCYEEISQEEVLSYAELCSALGVKQESPEPPSFPSSGEIHTFLSSPSGRRSKRKRENSLQEDRGSFVTTPTAELSNQEETLLGSLLDWSLDCCSGYEGDQESEGEKEGDVTAPSGLLDVTVVYLNPEEHCCQESSDEEVWPEDKSHPTPGTQAPPASAPWPLPCNRGDPGKDVTTSGYSSVSSSSPISSLDGGMVGSPRSTSVLSVGSHSSTKPCYHQAKKSCLQCRPPNPPESGAHQQPVKRQNLSVHSDEDTNLGFLKL", "length": 780 }, "evidence": [ { "id": "F1N6Y6", "url": "https://omabrowser.org/oma/group/F1N6Y6/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" } ], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 5, "go_terms": [ { "name": "nucleus", "id": "GO:0005634", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005634", "evidence": [ { "database": "UniProtKB", "id": "F1N6Y6", "url": "https://www.uniprot.org/uniprotkb/F1N6Y6" } ], "pmid": "" }, { "name": "perinuclear region of cytoplasm", "id": "GO:0048471", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0048471", "evidence": [ { "database": "UniProtKB", "id": "F1N6Y6", "url": "https://www.uniprot.org/uniprotkb/F1N6Y6" } ], "pmid": "" }, { "name": "centriole", "id": "GO:0005814", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005814", "evidence": [ { "database": "UniProtKB", "id": "F1N6Y6", "url": "https://www.uniprot.org/uniprotkb/F1N6Y6" } ], "pmid": "" }, { "name": "centrosome", "id": "GO:0005813", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005813", "evidence": [ { "database": "UniProtKB", "id": "F1N6Y6", "url": "https://www.uniprot.org/uniprotkb/F1N6Y6" } ], "pmid": "" }, { "name": "cilium", "id": "GO:0005929", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005929", "evidence": [ { "database": "UniProtKB", "id": "F1N6Y6", "url": "https://www.uniprot.org/uniprotkb/F1N6Y6" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 4, "go_terms": [ { "name": "cell division", "id": "GO:0051301", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0051301", "evidence": [ { "database": "UniProtKB", "id": "F1N6Y6", "url": "https://www.uniprot.org/uniprotkb/F1N6Y6" } ], "pmid": "" }, { "name": "negative regulation of centrosome duplication", "id": "GO:0010826", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0010826", "evidence": [ { "database": "UniProtKB", "id": "F1N6Y6", "url": "https://www.uniprot.org/uniprotkb/F1N6Y6" } ], "pmid": "" }, { "name": "positive regulation of smoothened signaling pathway", "id": "GO:0045880", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0045880", "evidence": [ { "database": "UniProtKB", "id": "F1N6Y6", "url": "https://www.uniprot.org/uniprotkb/F1N6Y6" } ], "pmid": "" }, { "name": "microtubule cytoskeleton organization", "id": "GO:0000226", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000226", "evidence": [ { "database": "UniProtKB", "id": "F1N6Y6", "url": "https://www.uniprot.org/uniprotkb/F1N6Y6" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 216, "end_pos": 218, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [ { "pdb_id": "AF-F1N6Y6-F1", "pdb_chain": "global", "start_pos": 1, "end_pos": 436, "overlap": "1.0", "method": "AlphaFold", "type": "alphafold", "resolution": -1.0, "url": "https://data.glygen.org/ln2downloads/pdb/current/AF-F1N6Y6-F1.pdb", "url_external": "https://alphafold.ebi.ac.uk/entry/F1N6Y6" } ], "lectin_list": [], "domain_list": [], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" }, { "name": "homologset.oma", "label": "OMA Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [ 53 ], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 216, "end_pos": 218 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 1 }, { "field": "total_sites", "count": 1 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 1 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "exact_sites", "count": 1 }, { "field": "exact_o_linked_sites", "count": 1 }, { "field": "fuzzy_sites", "count": 0 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_pos", "start_aa", "end_pos", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 1 }, { "field": "total_sites", "count": 1 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 1 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "exact_sites", "count": 1 }, { "field": "exact_o_linked_sites", "count": 1 }, { "field": "fuzzy_sites", "count": 0 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_pos", "start_aa", "end_pos", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": 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"publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ], "tool_support": { "graph_view": "yes" } }, { "uniprot_canonical_ac": "F1N451-1", "uniprot_ac": "F1N451", "uniprot_id": "F1N451_BOVIN", "mass": { "chemical_mass": 67636.0, "monoisotopic_mass": 67636.0 }, "refseq": { "ac": "XP_024838407", "name": "grainyhead-like protein 3 homolog isoform X2", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_024838407" }, "gene_names": [ { "name": "GRHL3", "type": "recommended", "evidence": [ { "id": "F1N451", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1N451" } ] }, { "name": "GRHL3", "type": "synonym", "evidence": [ { "id": "XP_024838407", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_024838407" } ] } ], "protein_names": [ { "name": "Grainyhead like transcription factor 3", "type": "synonym", "evidence": [ { "id": "F1N451", "database": "UniProtKB", "url": 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"https://alphafold.ebi.ac.uk/entry/F1N451", "database": "AlphaFoldDB", "categories": [] }, { "id": "ENSBTAG00000019791", "url": "https://bgee.org/?page=gene&gene_id=ENSBTAG00000019791", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "531906", "url": "https://www.ncbi.nlm.nih.gov/gene/531906", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR007604", "url": "https://www.ebi.ac.uk/interpro/entry/IPR007604", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR040167", "url": "https://www.ebi.ac.uk/interpro/entry/IPR040167", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR057520", "url": "https://www.ebi.ac.uk/interpro/entry/IPR057520", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "bta:531906", "url": "https://www.genome.jp/dbget-bin/www_bget?bta:531906", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "MDSWSYL", "url": "https://omabrowser.org/oma/group/MDSWSYL/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "A0A3Q1LH90", "url": "https://www.orthodb.org/?gene=A0A3Q1LH90", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "F1N451", "url": "https://www.orthodb.org/?gene=F1N451", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR11037", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR11037", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR11037:SF6", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR11037:SF6", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF04516", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF04516", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF25416", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF25416", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "XP_024838407", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_024838407", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A3Q1LH90", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1LH90", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A3Q1LH90-1", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1LH90-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0AAA9SCQ0", "url": "https://www.uniprot.org/uniprotkb/A0AAA9SCQ0", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0AAA9SCQ0-1", "url": "https://www.uniprot.org/uniprotkb/A0AAA9SCQ0-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0AAA9T396", "url": "https://www.uniprot.org/uniprotkb/A0AAA9T396", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0AAA9T396-1", "url": "https://www.uniprot.org/uniprotkb/A0AAA9T396-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0AAA9TH55", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TH55", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0AAA9TH55-1", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TH55-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0AAA9TP63", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TP63", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0AAA9TP63-1", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TP63-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0AAA9TY07", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TY07", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0AAA9TY07-1", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TY07-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0AAA9TYC1", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TYC1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0AAA9TYC1-1", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TYC1-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "F1N451", "url": "https://www.uniprot.org/uniprotkb/F1N451", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "F1N451-1", "url": "https://www.uniprot.org/uniprotkb/F1N451-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MSNELDFRSVRLLKNDPVNFQKFPYTNEDEAWKTYLENPLTAATKAMMRVNGDDDSVAALSFLYDYYMGPKEKRLLSSSTGGRNDQGKRYYHGMEYEMDLTPLESPTHLMKFLTENVSGTPEYPDVLKKNNLMSVEGAAPTPGKAALLPAGPSKLETGSVDSYLLPTSDVYDNGSLSSLFESIHGVPPTQRWQPDSTFKDDPQESLLFPDILKTSPEPPGPEDYPNPKSDFEYTLGSPKAIHIKSGESPMAYLNKGQFYPVTLRTPAGGKGLALSSNKVKSVVMVVFDNEKGPVEQLRFWKHWHSRQPTAKQRVIDVADCKENFNTVQHIEEVAYNALSFVWNVHEEAKVFVGVNCLSTDFSSQKGVKGVPLNLQIDTYDCGSGTERLVHRAVCQIKIFCDKGAERKMRDDERKQFRRKVKCPDSSNSGIKGSLLAGFRGNETTYLRPEADLETPPVLFIPNVHFSSLQRPGGAVLSAGHGSSNRLALKRTCSPFTEEFEPLPSKQAKEDDLQRVLLYVRRETEEVFDALMLKTPDLKGLRSAISEKYGFPEENIYKVYKKCKRGILVNMDNNIIRHYSNHVAFLLDMGELDGKIQIILKEL", "length": 602, "header": "tr|F1N451-1|F1N451_BOVIN Isoform 1 of Grainyhead like transcription factor 3 OS=Bos taurus OX=9913 GN=GRHL3 PE=4 SV=2 CANONICAL=F1N451-1" }, "isoforms": [ { "isoform_ac": "A0A3Q1LH90-1", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1LH90/entry", "sequence": { "sequence": "MRVNSVLPIFLFRSVRLLKNDPVNFQKFPYTNEDEAWKTYLENPLTAATKAMMRVNGDDDSVAALSFLYDYYMGPKEKRLLSSSTGGRNDQGKRYYHGMEYEMDLTPLESPTHLMKFLTENVSGTPEYPDVLKKNNLMSVEGAAPTPGKAALLPAGPSKLETGSVDSYLLPTSDVYDNGSLSSLFESIHGVPPTQRWQPDSTFKDDPQESLLFPDILKTSPEPPGPEDYPNPKSDFEYTLGSPKAIHIKSGESPMAYLNKGQFYPVTLRTPAGGKGLALSSNKVKSVVMVVFDNEKGPVEQLRFWKHWHSRQPTAKQRVIDVADCKENFNTVQHIEEVAYNALSFVWNVHEEAKVFVGVNCLSTDFSSQKGVKGVPLNLQIDTYDCGSGTERLVHRAVCQIKIFCDKGAERKMRDDERKQFRRKVKCPDSSNSGIKGSLLAGFRGNETTYLRPEADLETPPVLFIPNVHFSSLQRPGGAVLSAGHGSSNRLALKRTCSPFTEEFEPLPSKQAKEDDLQRVLLYVRRETEEVFDALMLKTPDLKGLRSAISEKYGFPEENIYKVYKKCKRGILVNMDNNIIRHYSNHVAFLLDMGELDGKIQIILKEL", "length": 607, "header": "tr|A0A3Q1LH90-1|F1N451_BOVIN Computationally mapped isoform of Grainyhead like transcription factor 3 OS=Bos taurus OX=9913 GN=GRHL3 PE=4 SV=2 CANONICAL=F1N451-1" }, "locus": { "chromosome": "2", "start_pos": 128596250, "end_pos": 128564820, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000084282.2", "url": "https://www.ensembl.org/id/ENSBTAT00000084282.2" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000058053.2", "url": "https://www.ensembl.org/id/ENSBTAP00000058053.2" } ] } }, { "isoform_ac": "A0AAA9SCQ0-1", "url": "https://www.uniprot.org/uniprotkb/A0AAA9SCQ0/entry", "sequence": { "sequence": "MSNELDFRSVRLLKNDPVNFQKFPYTNEDEAWKTYLENPLTAATKAMMRVNGDDDSVAALSFLYDYYMGPKEKRLLSSSTGGRNDQGKRYYHGMEYEMDLTPLESPTHLMKFLTENVSGTPEYPDVLKKNNLMSVEGAAPTPGKAALLPAGPSKLETGSVDSYLLPTSDVYDNGSLSSLFESIHGVPPTQRWQPDSTFKDDPQESLLFPDILKTSPEPPGPEDYPNPKSDFEYTLGSPKAIHIKSGESPMAYLNKGQFYPVTLRTPAGGKGLALSSNKVKSVVMVVFDNEKGPVEQLRFWKHWHSRQPTAKQRVIDVADCKENFNTVQHIEEVAYNALSFVWNVHEEAKVFVGVNCLSTDFSSQKGVKGVPLNLQIDTYDCGSGTERLVHRAVCQIKIFCDKGAERKMRDDERKQFRRKVKCPDSSNSGIKGSLLAGFRGNETTYLRPEADLETPPVLFIPNVHFSSLQRPGGAVLSAGHGSSNRLALKRTCSPFTEEFEPLPSKQAKEDDLQRVLLYVRRETEEVFDALMLKTPDLKGLRSAISEKYGFPEENIYKVYKKCKRGWPGVLCEPGQKTA", "length": 578, "header": "tr|A0AAA9SCQ0-1|F1N451_BOVIN Computationally mapped isoform of Grainyhead like transcription factor 3 OS=Bos taurus OX=9913 GN=GRHL3 PE=4 SV=1 CANONICAL=F1N451-1" }, "locus": { "chromosome": "2", "start_pos": 128599921, "end_pos": 128566664, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000111960.1", "url": "https://www.ensembl.org/id/ENSBTAT00000111960.1" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000083901.1", "url": "https://www.ensembl.org/id/ENSBTAP00000083901.1" } ] } }, { "isoform_ac": "A0AAA9T396-1", "url": "https://www.uniprot.org/uniprotkb/A0AAA9T396/entry", "sequence": { "sequence": "MCFNKPSSFRSVRLLKNDPVNFQKFPYTNEDEAWKTYLENPLTAATKAMMRVNGDDDSVAALSFLYDYYMGPKEKRLLSSSTGGRNDQGKRYYHGMEYEMDLTPLESPTHLMKFLTENVSGTPEYPDVLKKNNLMSVEGAAPTPGKAALLPAGPSKLETGSVDSYLLPTSDVYDNGSLSSLFESIHGVPPTQRWQPDSTFKDDPQESLLFPDILKTSPEPPGPEDYPNPKSDFEYTLGSPKAIHIKSGESPMAYLNKGQFYPVTLRTPAGGKGLALSSNKVKSVVMVVFDNEKGPVEQLRFWKHWHSRQPTAKQRVIDVADCKENFNTVQHIEEVAYNALSFVWNVHEEAKVFVGVNCLSTDFSSQKGVKGVPLNLQIDTYDCGSGTERLVHRAVCQIKIFCDKGAERKMRDDERKQFRRKVKCPDSSNSIKGSLLAGFRGNETTYLRPEADLETPPVLFIPNVHFSSLQRPGGAVLSAGHGSSNRLALKRTCSPFTEEFEPLPSKQAKEDDLQRVLLYVRRETEEVFDALMLKTPDLKGLRSAISEKYGFPEENIYKVYKKCKRGILVNMDNNIIRHYSNHVAFLLDMGELDGKIQIILKEL", "length": 603, "header": "tr|A0AAA9T396-1|F1N451_BOVIN Computationally mapped isoform of Grainyhead like transcription factor 3 OS=Bos taurus OX=9913 GN=GRHL3 PE=4 SV=1 CANONICAL=F1N451-1" }, "locus": { "chromosome": "2", "start_pos": 128595974, "end_pos": 128564820, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000128423.1", "url": "https://www.ensembl.org/id/ENSBTAT00000128423.1" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000093261.1", "url": "https://www.ensembl.org/id/ENSBTAP00000093261.1" } ] } }, { "isoform_ac": "A0AAA9TH55-1", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TH55/entry", "sequence": { "sequence": "MGFKLVRLPRILLKSWDLIRGRKNAPHQCVILLLTSMDVENCFRSVRLLKNDPVNFQKFPYTNEDEAWKTYLENPLTAATKAMMRVNGDDDSVAALSFLYDYYMGPKEKRLLSSSTGGRNDQGKRYYHGMEYEMDLTPLESPTHLMKFLTENVSGTPEYPDVLKKNNLMSVEGAAPTPGKAALLPAGPSKLETGSVDSYLLPTSDVYDNGSLSSLFESIHGVPPTQRWQPDSTFKDDPQESLLFPDILKTSPEPPGPEDYPNPKSDFEYTLGSPKAIHIKSGESPMAYLNKGQFYPVTLRTPAGGKGLALSSNKVKSVVMVVFDNEKGPVEQLRFWKHWHSRQPTAKQRVIDVADCKENFNTVQHIEEVAYNALSFVWNVHEEAKVFVGVNCLSTDFSSQKGVKGVPLNLQIDTYDCGSGTERLVHRAVCQIKIFCDKGAERKMRDDERKQFRRKVKCPDSSNSGIKGSLLAGFRGNETTYLRPEADLETPPVLFIPNVHFSSLQRPGGAVLSAGHGSSNRLALKRTCSPFTEEFEPLPSKQAKEDDLQRVLLYVRRETEEVFDALMLKTPDLKGLRSAISEKYGFPEENIYKVYKKCKRGILVNMDNNIIRHYSNHVAFLLDMGELDGKIQIILKEL", "length": 638, "header": "tr|A0AAA9TH55-1|F1N451_BOVIN Computationally mapped isoform of Grainyhead like transcription factor 3 OS=Bos taurus OX=9913 GN=GRHL3 PE=4 SV=1 CANONICAL=F1N451-1" }, "locus": { "chromosome": "2", "start_pos": 128596422, "end_pos": 128564820, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000104931.1", "url": "https://www.ensembl.org/id/ENSBTAT00000104931.1" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000096200.1", "url": "https://www.ensembl.org/id/ENSBTAP00000096200.1" } ] } }, { "isoform_ac": "A0AAA9TP63-1", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TP63/entry", "sequence": { "sequence": "MIPPFRSVRLLKNDPVNFQKFPYTNEDEAWKTYLENPLTAATKAMMRVNGDDDSVAALSFLYDYYMGPKEKRLLSSSTGGRNDQGKRYYHGMEYEMDLTPLESPTHLMKFLTENVSGTPEYPDVLKKNNLMSVEGAAPTPGKAALLPAGPSKLETGSVDSYLLPTSDVYDNGSLSSLFESIHGVPPTQRWQPDSTFKDDPQESLLFPDILKTSPEPPGPEDYPNPKSDFEYTLGSPKAIHIKSGESPMAYLNKGQFYPVTLRTPAGGKGLALSSNKVKSVVMVVFDNEKGPVEQLRFWKHWHSRQPTAKQRVIDVADCKENFNTVQHIEEVAYNALSFVWNVHEEAKVFVGVNCLSTDFSSQKGVKGVPLNLQIDTYDCGSGTERLVHRAVCQIKIFCDKGAERKMRDDERKQFRRKVKCPDSSNSGIKGSLLAGFRGNETTYLRPEADLETPPVLFIPNVHFSSLQRPGGAVLSAGHGSSNRLALKRTCSPFTEEFEPLPSKQAKEDDLQRVLLYVRRETEEVFDALMLKTPDLKGLRSAISEKYGFPEENIYKVYKKCKRGILVNMDNNIIRHYSNHVAFLLDMGELDGKIQIILKEL", "length": 600, "header": "tr|A0AAA9TP63-1|F1N451_BOVIN Computationally mapped isoform of Grainyhead like transcription factor 3 OS=Bos taurus OX=9913 GN=GRHL3 PE=4 SV=1 CANONICAL=F1N451-1" }, "locus": { "chromosome": "2", "start_pos": 128593908, "end_pos": 128564820, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000114493.1", "url": "https://www.ensembl.org/id/ENSBTAT00000114493.1" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000098142.1", "url": "https://www.ensembl.org/id/ENSBTAP00000098142.1" } ] } }, { "isoform_ac": "A0AAA9TY07-1", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TY07/entry", "sequence": { "sequence": "MSNELDFRSVRLLKNDPVNFQKFPYTNEDEAWKTYLENPLTAATKAMMRVNGDDDSVAALSFLYDYYMGPKEKRLLSSSTGGRNDQGKRYYHGMEYEMDLTPLESPTHLMKFLTENVSGTPEYPDVLKKNNLMSVEGAAPTPGKAALLPAGPSKLETGSVDSYLLPTSDVYDNGSLSSLFESIHGVPPTQRWQPDSTFKDDPQESLLFPDILKTSPEPPGPEDYPNPKSDFEYTLGSPKAIHIKSGESPMAYLNKGQFYPVTLRTPAGGKGLALSSNKVKSVVMVVFDNEKGPVEQLRFWKHWHSRQPTAKQRVIDVADCKENFNTVQHIEEVAYNALSFVWNVHEEAKVFVGVNCLSTDFSSQKGVKGVPLNLQIDTYDCGSGTERLVHRAVCQIKIFCDKGAERKMRDDERKQFRRKVKCPDSSNSGIKGSLLAGFRGNETTYLRPEADLETPPVLFIPNVHFSSLQRPGGAVLSAGHGSSNRLALKRTCSPFTEEFEPLPSKQAKEDDLQRVLLYVRRETEEVFDALMLKTPDLKGLRSAISEKYGFPEENIYKVYKKCKRGQRIEAWRCQAA", "length": 576, "header": "tr|A0AAA9TY07-1|A0AAA9TY07_BOVIN Computationally mapped isoform of Grainyhead like transcription factor 3 OS=Bos taurus OX=9913 GN=GRHL3 PE=4 SV=1 CANONICAL=F1N451-1" }, "locus": { "chromosome": "2", "start_pos": 128599921, "end_pos": 128568774, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000113641.1", "url": "https://www.ensembl.org/id/ENSBTAT00000113641.1" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000102380.1", "url": "https://www.ensembl.org/id/ENSBTAP00000102380.1" } ] } }, { "isoform_ac": "A0AAA9TYC1-1", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TYC1/entry", "sequence": { "sequence": "MSNELDFRSVRLLKNDPVNFQKFPYTNEDEAWKTYLENPLTAATKAMMRVNGDDDSVAALSFLYDYYMGPKEKRLLSSSTGGRNDQGKRYYHGMEYEMDLTPLESPTHLMKFLTENVSGTPEYPDVLKKNNLMSVEGAAPTPGKAALLPAGPSKLETGSVDSYLLPTSDVYDNGSLSSLFESIHGVPPTQRWQPDSTFKDDPQESLLFPDILKTSPEPPGPEDYPNPKSDFEYTLGSPKAIHIKSGESPMAYLNKGQFYPVTLRTPAGGKGLALSSNKVKSVVMVVFDNEKGPVEQLRFWKHWHSRQPTAKQRVIDVADCKENFNTVQHIEEVAYNALSFVWNVHEEAKVFVGVNCLSTDFSSQKGVKGVPLNLQIDTYDCGSGTERLVHRAVCQIKIFCDKGAERKMRDDERKQFRRKVKCPDSSNSGIKGSLLAGFRGNETTYLRPEADLETPPVLFIPNVHFSSLQRPGGAVLSAGHGSSNRLALKRTCSPFTEEFEPLPSKQAKEDDLQRVLLYVRRETEEVFDALMLKTPDLKGLRSAEDSGKEYSGTLTFCWPTHPAPSEGACGAWLWGGGVGRCASEMLSPNQTLGSTRGAAHTINPP", "length": 605, "header": "tr|A0AAA9TYC1-1|A0AAA9TYC1_BOVIN Computationally mapped isoform of Grainyhead like transcription factor 3 OS=Bos taurus OX=9913 GN=GRHL3 PE=4 SV=1 CANONICAL=F1N451-1" }, "locus": { "chromosome": "2", "start_pos": 128599921, "end_pos": 128571546, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000132437.1", "url": "https://www.ensembl.org/id/ENSBTAT00000132437.1" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000103631.1", "url": "https://www.ensembl.org/id/ENSBTAP00000103631.1" } ] } }, { "isoform_ac": "F1N451-1", "url": "https://www.uniprot.org/uniprotkb/F1N451/entry", "sequence": { "sequence": "MSNELDFRSVRLLKNDPVNFQKFPYTNEDEAWKTYLENPLTAATKAMMRVNGDDDSVAALSFLYDYYMGPKEKRLLSSSTGGRNDQGKRYYHGMEYEMDLTPLESPTHLMKFLTENVSGTPEYPDVLKKNNLMSVEGAAPTPGKAALLPAGPSKLETGSVDSYLLPTSDVYDNGSLSSLFESIHGVPPTQRWQPDSTFKDDPQESLLFPDILKTSPEPPGPEDYPNPKSDFEYTLGSPKAIHIKSGESPMAYLNKGQFYPVTLRTPAGGKGLALSSNKVKSVVMVVFDNEKGPVEQLRFWKHWHSRQPTAKQRVIDVADCKENFNTVQHIEEVAYNALSFVWNVHEEAKVFVGVNCLSTDFSSQKGVKGVPLNLQIDTYDCGSGTERLVHRAVCQIKIFCDKGAERKMRDDERKQFRRKVKCPDSSNSGIKGSLLAGFRGNETTYLRPEADLETPPVLFIPNVHFSSLQRPGGAVLSAGHGSSNRLALKRTCSPFTEEFEPLPSKQAKEDDLQRVLLYVRRETEEVFDALMLKTPDLKGLRSAISEKYGFPEENIYKVYKKCKRGILVNMDNNIIRHYSNHVAFLLDMGELDGKIQIILKEL", "length": 602, "header": "tr|F1N451-1|F1N451_BOVIN Isoform 1 of Grainyhead like transcription factor 3 OS=Bos taurus OX=9913 GN=GRHL3 PE=4 SV=2 CANONICAL=F1N451-1" }, "locus": { "chromosome": "2", "start_pos": 128599921, "end_pos": 128564820, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000026370.6", "url": "https://www.ensembl.org/id/ENSBTAT00000026370.6" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000026370.5", "url": "https://www.ensembl.org/id/ENSBTAP00000026370.5" } ] } } ], "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "other", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 141, "start_aa": "Thr", "end_pos": 141, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr141", "evidence": [ { "id": "", "database": "GlyGen", "url": "https://data.glygen.org/" } ], "filter_code": "000000000000000010000.00000000001000.0.01000" } ], "phosphorylation": [], "glycation": [], "keywords": [ "glycoprotein", "glycoprotein_predicted" ], "publication": [], "pathway": [ { "id": "bta:531906", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?bta:531906", "resource": "KEGG Pathway" } ], "orthologs": [ { "uniprot_canonical_ac": "A0A1D5PGS7-1", "protein_name": "Grainyhead like transcription factor 3", "gene_name": "GRHL3", "tax_id": 9031, "organism": "Gallus gallus", "sequence": { "sequence": "MERPGESARREEEGQYFGALLLSTHSPMSLSSDSFRSVRLMKNDTMNFQKFSYTNEDEAWKTYLENPLTAATKAMMRVNGDDDSVAALSLLYDYYMVPKEKRILPSGMMGRNELGKRQYHGMEYDSDITSFDGSAHLMKLLSENTSMTQEYCEPQKKNGLSLEGIPTPHKPAMLPPGTSKLDATPDTYMVPPGDLYDNSALNSLFETNPVATPQQRWQPDSTFKEDPQESLLFSDILKPQPEPPCSESYPTDGVKSDFEYTLGSPKAIHIKSGDSPMAYLNKGQFYPITLRAAGDSKCLHLSSNKVKSVVMIVFDNEKIPTEQLKFWKHWHSRQPTAKQRVIDVADCKENFNTVQNIEELAYNALSFVWNIHEEAKVFIGVNCLSTDFSSQKGVKGVPLNLQIDTYDYGNGTNHLVHRAVCQIKIFCDKGAERKMRDDERKQFRRKGKCLDSNNNGLKGCLLSGFRGNEITFLRPETDLETQPVLFIPNLHFSNQQRCGTALPPAVPNSANRLPLKRSGTSFTDEFDPVPPKQTKEEDPQRVLLYVRRESEEVFDALMLKTPDLQGLRMAISEKYGLPEESIYKVYKKCKRGILVNMDNNIIQHYSNHMAFLLDMVEAEDKIQVILKEL", "length": 629 }, "evidence": [ { "id": "F1N451", "url": "https://omabrowser.org/oma/group/F1N451/", "database": "OMA" } ], "glygen_name": "Chicken", "common_name": "Chicken" }, { "uniprot_canonical_ac": "A0A287B8R5-1", "protein_name": "Grainyhead like transcription factor 3", "gene_name": "GRHL3", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MSNELDFRSVRLLKNDPVNFQKFPYTTEDEAWKTYLENPLTAATKAMMRVNGDDDSVAALSFLYDYYMGPKEKRILSSSTGGRNDQGKRYYHGMECEMDLTPLESPTHLMKFLTENVSGTPEYPDVLKKSSLMSLEGAAPAAGKAALLPPGPSKLEAGSVDSYLLPTSDVYDNGSLSSLFESIHGVPPTQRWQPDSTFKDDPQESLLFPDILKTSQEPPCPEDYPSPKSDFEYTLGSPKAIHIKSGESPMAYLNKGQFYPVTLRTPAGGKGLALSSNKVKSVVMVVFDNEKVPLEQLRFWKHWHSRQPTAKQRVIDVADCKENFNTVQHIEEVAYNALSFVWNVNEEAKVFIGVNCLSTDFSSQKGVKGVPLNLQIDTYDCGSGTERLVHRAVCQIKIFCDKGAERKMRDDERKQFRRKIKCPDSSNSGIKGSLLSGFRGNETTYLRPEADLETPPVLFIPNVHFSGLQRSGGAVLSAGHSSSNRLPLKRTCSPFTEEFEPLPSKQAKEDDLQRVLLYVRRETEEVFDALMLKTPDLKGLRNAISEKYGFPEENIHKVYKKCKRGILVNMDNNIIQHYSNHVAFLLDMGELDGKIQIILKEL", "length": 602 }, "evidence": [ { "id": "F1N451", "url": "https://omabrowser.org/oma/group/F1N451/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "A0A8I5ZM46-1", "protein_name": "Grainyhead-like transcription factor 3", "gene_name": "Grhl3", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MSNELDFRSVRLLKNDPVSFQKFPYNNEDEAWKTYLENPLTAATKAIMRVNGDDESVAALSFLYDYYMGPKEKRILSSSTGGRNDQGKKYYHSMDYEPDLAPLESPTHLMKFLTENVSGSPDYTDQLKKNNLLGLEGALPTPGKTSTLPPGPSKLEAGSMDSYLLPTSDMYDNSSLNSLFESIHGVPPTQRWQPDSTFKDDPQESLLFPDILKTSPEAPCPEDYPSLKSDFEYTLGSPKAIHIKAGESPMAYLNKGQFYPVTLRTPAGGKGLSLSSSKVKSVVMIVFDNDKVPVEQLRFWRHWHSRQPTAKQRVIDVADCKENFNTVQHIEEVAYNALSFVWNVNEEAKVFIGVNCLSTDFSSQKGVKGVPLNLQIDTYDCGAGTERLVHRAVCQIKIFCDKGAERKMRDDERKQFRRKVKCPDSSNNAGIKGCLLSGFRGNETTYLRPEADLETQPVLFIPNLHFSSLQRPGGVVPSAGHSSSDRLPLKRTCSPFAEEFEPLPSKQAKEDDLQRVLLYVRRETEEVFDALMLKTPDLKGLRNAISEKYGFPEENICKVYKKCKRGILVNMDNNIIQHYSNHVAFLLDMGELDGKIQIILKEL", "length": 603 }, "evidence": [ { "id": "F1N451", "url": "https://omabrowser.org/oma/group/F1N451/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "Q5FWH3-1", "protein_name": "Grainyhead-like protein 3 homolog", "gene_name": "Grhl3", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MSNELDFRSVRLLKNDPVSFQKFPYSNEDEAWKTYLENPLTAATKAMMRVNGDEESVAALSFLYDYYMGPKEKRILSSSTGGRNDQGKKFYHSMDYEPDLAPLESPTHLMKFLTENVSGSPDYTDQLKKNNLLGLEGVLPTPGKTNTVPPGPSKLEASSMDSYLLPASDIYDNGSLNSLFESIHGVPPTQRWQPDSTFKDDPQESLLFPDILKTSPDPPCPEDYPGLKSDFEYTLGSPKAIHIKAGESPMAYLNKGQFYPVTLRTPAGGKGLALSSSKVKSVVMVVFDNDKVPVEQLRFWRHWHSRQPTAKQRVIDVADCKENFNTVQHIEEVAYNALSFVWNVNEEAKVFIGVNCLSTDFSSQKGVKGVPLNLQIDTYDCGAGTERLVHRAVCQIKIFCDKGAERKMRDDERKQFRRKVKCPDSSNNAGIKGCLLSGFRGNETTYLRPETDLETQPVLFIPNLHFSSLQRPGGVVPSAGHSSSDRLPLKRTCSPFAEEFEPLPSKQAKEDDLQRVLLYVRRETEEVFDALMLKTPDLKGLRNAISEKYGLPEENICKVYKKCKRGILVNMDNNIIQHYSNHVAFLLDMGELDGKIQIILKEL", "length": 603 }, "evidence": [ { "id": "F1N451", "url": "https://omabrowser.org/oma/group/F1N451/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q8TE85-1", "protein_name": "Grainyhead-like protein 3 homolog", "gene_name": "GRHL3", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MSNELDFRSVRLLKNDPVNLQKFSYTSEDEAWKTYLENPLTAATKAMMRVNGDDDSVAALSFLYDYYMGPKEKRILSSSTGGRNDQGKRYYHGMEYETDLTPLESPTHLMKFLTENVSGTPEYPDLLKKNNLMSLEGALPTPGKAAPLPAGPSKLEAGSVDSYLLPTTDMYDNGSLNSLFESIHGVPPTQRWQPDSTFKDDPQESMLFPDILKTSPEPPCPEDYPSLKSDFEYTLGSPKAIHIKSGESPMAYLNKGQFYPVTLRTPAGGKGLALSSNKVKSVVMVVFDNEKVPVEQLRFWKHWHSRQPTAKQRVIDVADCKENFNTVEHIEEVAYNALSFVWNVNEEAKVFIGVNCLSTDFSSQKGVKGVPLNLQIDTYDCGLGTERLVHRAVCQIKIFCDKGAERKMRDDERKQFRRKVKCPDSSNSGVKGCLLSGFRGNETTYLRPETDLETPPVLFIPNVHFSSLQRSGGAAPSAGPSSSNRLPLKRTCSPFTEEFEPLPSKQAKEGDLQRVLLYVRRETEEVFDALMLKTPDLKGLRNAISEKYGFPEENIYKVYKKCKRGETSLLHPRLSRHPPPDCLECSHPVTQVRNMGFGDGFWRQRDLDSNPSPTTVNSLHFTVNSE", "length": 626 }, "evidence": [ { "id": "F1N451", "url": "https://omabrowser.org/oma/group/F1N451/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" } ], "go_annotation": { "categories": [ { "name": "Molecular Function", "total": 5, "go_terms": [ { "name": "DNA binding", "id": "GO:0003677", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003677", "evidence": [ { "database": "UniProtKB", "id": "F1N451", "url": "https://www.uniprot.org/uniprotkb/F1N451" } ], "pmid": "" }, { "name": "DNA-binding transcription factor activity", "id": "GO:0003700", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003700", "evidence": [ { "database": "UniProtKB", "id": "F1N451", "url": "https://www.uniprot.org/uniprotkb/F1N451" } ], "pmid": "" }, { "name": "RNA polymerase II cis-regulatory region sequence-specific DNA binding", "id": "GO:0000978", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000978", "evidence": [ { "database": "UniProtKB", "id": "F1N451", "url": "https://www.uniprot.org/uniprotkb/F1N451" } ], "pmid": "" }, { "name": "chromatin DNA binding", "id": "GO:0031490", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0031490", "evidence": [ { "database": "UniProtKB", "id": "F1N451", "url": "https://www.uniprot.org/uniprotkb/F1N451" } ], "pmid": "" }, { "name": "DNA-binding transcription activator activity, RNA polymerase II-specific", "id": "GO:0001228", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0001228", "evidence": [ { "database": "UniProtKB", "id": "F1N451", "url": "https://www.uniprot.org/uniprotkb/F1N451" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 2, "go_terms": [ { "name": "nucleus", "id": "GO:0005634", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005634", "evidence": [ { "database": "UniProtKB", "id": "F1N451", "url": "https://www.uniprot.org/uniprotkb/F1N451" } ], "pmid": "" }, { "name": "nucleoplasm", "id": "GO:0005654", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005654", "evidence": [ { "database": "UniProtKB", "id": "F1N451", "url": "https://www.uniprot.org/uniprotkb/F1N451" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 4, "go_terms": [ { "name": "DNA-templated transcription", "id": "GO:0006351", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006351", "evidence": [ { "database": "UniProtKB", "id": "F1N451", "url": "https://www.uniprot.org/uniprotkb/F1N451" } ], "pmid": "" }, { "name": "regulation of transcription by RNA polymerase II", "id": "GO:0006357", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006357", "evidence": [ { "database": "UniProtKB", "id": "F1N451", "url": "https://www.uniprot.org/uniprotkb/F1N451" } ], "pmid": "" }, { "name": "establishment of skin barrier", "id": "GO:0061436", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0061436", "evidence": [ { "database": "UniProtKB", "id": "F1N451", "url": "https://www.uniprot.org/uniprotkb/F1N451" } ], "pmid": "" }, { "name": "neural tube closure", "id": "GO:0001843", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0001843", "evidence": [ { "database": "UniProtKB", "id": "F1N451", "url": "https://www.uniprot.org/uniprotkb/F1N451" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 116, "end_pos": 118, "annotation": "n_glycosylation_sequon" }, { "start_pos": 173, "end_pos": 175, "annotation": "n_glycosylation_sequon" }, { "start_pos": 441, "end_pos": 443, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "F1N451", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1N451" }, { "id": "PS51968", "database": "PROSITE", "url": "https://prosite.expasy.org/PS51968" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "Grh/CP2 DB", "eco_id": "ECO_0000259", "start_pos": 227, "end_pos": 460, "start_aa": "Pro", "end_aa": "Ile", "glycosite_overlap": [] } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" }, { "name": "homologset.oma", "label": "OMA Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [ 141 ], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 116, "end_pos": 118 }, { "start_pos": 173, "end_pos": 175 }, { "start_pos": 441, "end_pos": 443 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 1 }, { "field": "total_sites", "count": 1 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 1 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "exact_sites", "count": 1 }, { "field": "exact_o_linked_sites", "count": 1 }, { "field": "fuzzy_sites", "count": 0 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_pos", "start_aa", "end_pos", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 1 }, { "field": "total_sites", "count": 1 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 1 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "exact_sites", "count": 1 }, { "field": "exact_o_linked_sites", "count": 1 }, { "field": "fuzzy_sites", "count": 0 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_pos", "start_aa", "end_pos", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ], "tool_support": { "graph_view": "yes" } }, { "uniprot_canonical_ac": "F1N6D6-1", "uniprot_ac": "F1N6D6", "uniprot_id": "F1N6D6_BOVIN", "mass": { "chemical_mass": 88166.0, "monoisotopic_mass": 88166.0 }, "refseq": {}, "gene_names": [ { "name": "CMIP", "type": "recommended", "evidence": [ { "id": "F1N6D6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1N6D6" } ] } ], "protein_names": [ { "name": "C-Maf-inducing protein", "type": "recommended", "evidence": [ { "id": "F1N6D6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1N6D6/entry#names_and_taxonomy" } ] } ], "function": [], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Bos taurus", "taxid": 9913, "evidence": [ { "database": "UniProtKB", "id": "F1N6D6", "url": "https://www.uniprot.org/uniprotkb/F1N6D6" } ], "common_name": "Bovine", "glygen_name": "Bovine", "reference_species": "Bos taurus [9913]" } ], "gene": [ { "name": "CMIP", "url": "https://www.uniprot.org/uniprotkb/F1N6D6", "locus": { "chromosome": "18", "start_pos": 8256468, "end_pos": 8042562, "strand": "-", "evidence": [ { "database": "Ensembl Gene", "id": "ENSBTAG00000013524", "url": "https://www.ensembl.org/id/ENSBTAG00000013524" } ] } } ], "crossref": [ { "id": "F1N6D6", "url": "https://alphafold.ebi.ac.uk/entry/F1N6D6", "database": "AlphaFoldDB", "categories": [] }, { "id": "ENSBTAG00000013524", "url": "https://bgee.org/?page=gene&gene_id=ENSBTAG00000013524", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "782414", "url": "https://www.ncbi.nlm.nih.gov/gene/782414", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR032675", "url": "https://www.ebi.ac.uk/interpro/entry/IPR032675", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR052813", "url": "https://www.ebi.ac.uk/interpro/entry/IPR052813", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR056429", "url": "https://www.ebi.ac.uk/interpro/entry/IPR056429", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "bta:782414", "url": "https://www.genome.jp/dbget-bin/www_bget?bta:782414", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "DECIYQT", "url": "https://omabrowser.org/oma/group/DECIYQT/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "F1N6D6", "url": "https://www.orthodb.org/?gene=F1N6D6", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR25480", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR25480", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR25480:SF0", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR25480:SF0", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF23066", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF23066", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "A0A3Q1LHU0", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1LHU0", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A3Q1LHU0-1", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1LHU0-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A3Q1N1I6", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1N1I6", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A3Q1N1I6-1", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1N1I6-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "F1N6D6", "url": "https://www.uniprot.org/uniprotkb/F1N6D6", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "F1N6D6-1", "url": "https://www.uniprot.org/uniprotkb/F1N6D6-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MSSLQRDTHRALTSTQVPALAWLGSGGGDPRQIEETKPLLGGDVPAPEGTKMGAVPCRRALLLCNGMRYKLLQEGDIQVCVIRHPRTFLSKILTSKFLRRWEPHHLTLADNSLASATPTGYMENSVSYSAIEDVQLLSWENAPKYCLQLTIPGGTVLLQAANSYLRDQWFHSLQWKKKIYKYKKVLSNPSRWEVVLKEIRTLVDMALTSPLQDDSINQAPLEIVSKLLSENTNLTTQEHENIIVAIAPLLENNHPPPDLCEFFCKHCRERPRSMVVIEVFTPVVQRILKHNMDFGKCPRLRLFTQEYILALNELNAGMEVVKKFIQSMHGPTGHCPHPRVLPNLVAVCLAAIYSCYEEFINSRDNSPSLKEIRNGCQQPCDRKPTLPLRLLHPSPDLVSQEATLSEARLKSVVVASSEIHVEVEPASTAKPALTASAGDDNEPNLIDCLMVSPACSTMSIELGPQADRTLGCYVEILKLLSDYDDWRPSLASLLQPIPFPKEALAHEKFTKELKYVIQRFAEDPRQEVHSCLLSVRAGKDGWFQLYSPGGVACDDDGELFASMVHILMGSCYKTKKFLLSLAENKLGPCMLLALRGNQTMVEILCLMLEYNIIDNNDTQLQIISTLESTGVGKRMYEQLCDRQRELKELQRKGGPTRLTLPSKSTDADLARLLSSGSFGNLENLSLAFTNVTSACAEHLIKLPSLKQLNLWSTQFGDAGLRLLSEHLTMLQVLNLCETPVTDAGLLALSSMKSLCSLNMNSTKLSADTYEDLKAKLPNLKEVDVRYTEAW", "length": 790, "header": "tr|F1N6D6-1|F1N6D6_BOVIN Isoform 1 of C-Maf-inducing protein OS=Bos taurus OX=9913 GN=CMIP PE=4 SV=3 CANONICAL=F1N6D6-1" }, "isoforms": [ { "isoform_ac": "A0A3Q1LHU0-1", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1LHU0/entry", "sequence": { "sequence": "MAEVAQKKIYKYKKVLSNPSRWEVVLKEIRTLVDMALTSPLQDDSINQAPLEIVSKLLSENTNLTTQEHENIIVAIAPLLENNHPPPDLCEFFCKHCRERPRSMVVIEVFTPVVQRILKHNMDFGKCPRLRLFTQEYILALNELNAGMEVVKKFIQSMHGPTGHCPHPRVLPNLVAVCLAAIYSCYEEFINSRDNSPSLKEIRNGCQQPCDRKPTLPLRLLHPSPDLVSQEATLSEARLKSVVVASSEIHVEVEPASTAKPALTASAGDDNEPNLIDCLMVSPACSTMSIELGPQADRTLGCYVEILKLLSDYDDWRPSLASLLQPIPFPKEALAHEKFTKELKYVIQRFAEDPRQEVHSCLLSVRAGKDGWFQLYSPGGVACDDDGELFASMVHILMGSCYKTKKFLLSLAENKLGPCMLLALRGNQTMVEILCLMLEYNIIDNNDTQLQIISTLESTGVGKRMYEQLCDRQRELKELQRKGGPTRLTLPSKSTDADLARLLSSGSFGNLENLSLAFTNVTSACAEHLIKLPSLKQLNLWSTQFGDAGLRLLSEHLTMLQVLNLCETPVTDAGLLALSSMKSLCSLNMNSTKLSADTYEDLKAKLPNLKEVDVRYTEAW", "length": 620, "header": "tr|A0A3Q1LHU0-1|F1N6D6_BOVIN Computationally mapped isoform of C-Maf-inducing protein OS=Bos taurus OX=9913 GN=CMIP PE=4 SV=3 CANONICAL=F1N6D6-1" }, "locus": { "chromosome": "18", "start_pos": 8255464, "end_pos": 8203042, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000087056.3", "url": "https://www.ensembl.org/id/ENSBTAT00000087056.3" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000058400.3", "url": "https://www.ensembl.org/id/ENSBTAP00000058400.3" } ] } }, { "isoform_ac": "A0A3Q1N1I6-1", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1N1I6/entry", "sequence": { "sequence": "MGPAAGPTGYMENSVSYSAIEDVQLLSWENAPKYCLQLTIPGGTVLLQAANSYLRDQWFHSLQWKKKIYKYKKVLSNPSRWEVVLKEIRTLVDMALTSPLQDDSINQAPLEIVSKLLSENTNLTTQEHENIIVAIAPLLENNHPPPDLCEFFCKHCRERPRSMVVIEVFTPVVQRILKHNMDFGKCPRLRLFTQEYILALNELNAGMEVVKKFIQSMHGPTGHCPHPRVLPNLVAVCLAAIYSCYEEFINSRDNSPSLKEIRNGCQQPCDRKPTLPLRLLHPSPDLVSQEATLSEARLKSVVVASSEIHVEVEPASTAKPALTASAGDDNEPNLIDCLMVSPACSTMSIELGPQADRTLGCYVEILKLLSDYDDWRPSLASLLQPIPFPKEALAHEKFTKELKYVIQRFAEDPRQEVHSCLLSVRAGKDGWFQLYSPGGVACDDDGELFASMVHILMGSCYKTKKFLLSLAENKLGPCMLLALRGNQTMVEILCLMLEYNIIDNNDTQLQIISTLESTGVGKRMYEQLCDRQRELKELQRKGGPTRLTLPSKSTDADLARLLSSGSFGNLENLSLAFTNVTSACAEHLIKLPSLKQLNLWSTQFGDAGLRLLSEHLTMLQVLNLCETPVTDAGLLALSSMKSLCSLNMNSTKLSADTYEDLKAKLPNLKEVDVRYTEAW", "length": 679, "header": "tr|A0A3Q1N1I6-1|F1N6D6_BOVIN Computationally mapped isoform of C-Maf-inducing protein OS=Bos taurus OX=9913 GN=CMIP PE=4 SV=2 CANONICAL=F1N6D6-1" }, "locus": { "chromosome": "18", "start_pos": 8255464, "end_pos": 8089784, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000071334.3", "url": "https://www.ensembl.org/id/ENSBTAT00000071334.3" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000062919.2", "url": "https://www.ensembl.org/id/ENSBTAP00000062919.2" } ] } }, { "isoform_ac": "F1N6D6-1", "url": "https://www.uniprot.org/uniprotkb/F1N6D6/entry", "sequence": { "sequence": "MSSLQRDTHRALTSTQVPALAWLGSGGGDPRQIEETKPLLGGDVPAPEGTKMGAVPCRRALLLCNGMRYKLLQEGDIQVCVIRHPRTFLSKILTSKFLRRWEPHHLTLADNSLASATPTGYMENSVSYSAIEDVQLLSWENAPKYCLQLTIPGGTVLLQAANSYLRDQWFHSLQWKKKIYKYKKVLSNPSRWEVVLKEIRTLVDMALTSPLQDDSINQAPLEIVSKLLSENTNLTTQEHENIIVAIAPLLENNHPPPDLCEFFCKHCRERPRSMVVIEVFTPVVQRILKHNMDFGKCPRLRLFTQEYILALNELNAGMEVVKKFIQSMHGPTGHCPHPRVLPNLVAVCLAAIYSCYEEFINSRDNSPSLKEIRNGCQQPCDRKPTLPLRLLHPSPDLVSQEATLSEARLKSVVVASSEIHVEVEPASTAKPALTASAGDDNEPNLIDCLMVSPACSTMSIELGPQADRTLGCYVEILKLLSDYDDWRPSLASLLQPIPFPKEALAHEKFTKELKYVIQRFAEDPRQEVHSCLLSVRAGKDGWFQLYSPGGVACDDDGELFASMVHILMGSCYKTKKFLLSLAENKLGPCMLLALRGNQTMVEILCLMLEYNIIDNNDTQLQIISTLESTGVGKRMYEQLCDRQRELKELQRKGGPTRLTLPSKSTDADLARLLSSGSFGNLENLSLAFTNVTSACAEHLIKLPSLKQLNLWSTQFGDAGLRLLSEHLTMLQVLNLCETPVTDAGLLALSSMKSLCSLNMNSTKLSADTYEDLKAKLPNLKEVDVRYTEAW", "length": 790, "header": "tr|F1N6D6-1|F1N6D6_BOVIN Isoform 1 of C-Maf-inducing protein OS=Bos taurus OX=9913 GN=CMIP PE=4 SV=3 CANONICAL=F1N6D6-1" }, "locus": { "chromosome": "18", "start_pos": 8255464, "end_pos": 8042957, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000017983.7", "url": "https://www.ensembl.org/id/ENSBTAT00000017983.7" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000017983.6", "url": "https://www.ensembl.org/id/ENSBTAP00000017983.6" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [ { "id": "bta:782414", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?bta:782414", "resource": "KEGG Pathway" } ], "orthologs": [ { "uniprot_canonical_ac": "Q8IY22-1", "protein_name": "C-Maf-inducing protein", "gene_name": "CMIP", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MDVTSSSGGGGDPRQIEETKPLLGGDVSAPEGTKMGAVPCRRALLLCNGMRYKLLQEGDIQVCVIRHPRTFLSKILTSKFLRRWEPHHLTLADNSLASATPTGYMENSVSYSAIEDVQLLSWENAPKYCLQLTIPGGTVLLQAANSYLRDQWFHSLQWKKKIYKYKKVLSNPSRWEVVLKEIRTLVDMALTSPLQDDSINQAPLEIVSKLLSENTNLTTQEHENIIVAIAPLLENNHPPPDLCEFFCKHCRERPRSMVVIEVFTPVVQRILKHNMDFGKCPRLRLFTQEYILALNELNAGMEVVKKFIQSMHGPTGHCPHPRVLPNLVAVCLAAIYSCYEEFINSRDNSPSLKEIRNGCQQPCDRKPTLPLRLLHPSPDLVSQEATLSEARLKSVVVASSEIHVEVERTSTAKPALTASAGNDSEPNLIDCLMVSPACSTMSIELGPQADRTLGCYVEILKLLSDYDDWRPSLASLLQPIPFPKEALAHEKFTKELKYVIQRFAEDPRQEVHSCLLSVRAGKDGWFQLYSPGGVACDDDGELFASMVHILMGSCYKTKKFLLSLAENKLGPCMLLALRGNQTMVEILCLMLEYNIIDNNDTQLQIISTLESTDVGKRMYEQLCDRQRELKELQRKGGPTRLTLPSKSTDADLARLLSSGSFGNLENLSLAFTNVTSACAEHLIKLPSLKQLNLWSTQFGDAGLRLLSEHLTMLQVLNLCETPVTDAGLLALSSMKSLCSLNMNSTKLSADTYEDLKAKLPNLKEVDVRYTEAW", "length": 773 }, "evidence": [ { "id": "F1N6D6", "url": "https://omabrowser.org/oma/group/F1N6D6/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "Q9D486-1", "protein_name": "C-Maf-inducing protein", "gene_name": "Cmip", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MDVTSSSGGGDPRQIEETKPLLGSDVSGPEGTKVMGAVPCRRALLLCNGMRYKLLQEGDIQVCVIRHPRTFLSKILTSKFLRRWEPHHLTLADNSLASATPSGYMENSVSYSAIEDVQPLSWENAPKYCLQLTIPGGTVLLQAANSYLRDQWFHSLQWKKKIYKYKKVLSNPSRWEVVLKEIRTLVDMALTSPLQDDSINQAPLEIVSKLLSENTNLTTQEHENIIVAIAPLLENNHPPPDLCEFFCKHCRERPRSMVVIEVFTPVVQRILKHNMDFGKCPRLRLFTQEYILALNELNAGMEVVKKFIQSMHGPTGHCPHPRVLPNLVAVCLAAIYSCYEEFINSRDNSPSLKEIRNGCQQPCDRKPTLPLRLLHPSPDLVSQEATLSEPRLKSVVVASSEVHVEVERTSTAKPALTASTGNDSEPNLIDCLMVSPACGTMSIELGPQAGRTLGCHVEILKLLSDYDDWRPSLASLLQPIPFPKEALAHEKFTKELKYVIQRFAEDPRQEVHSCLLSVRAGKDGWFQLYSPGGVACDDDGELFASMVHILMGSCYKTKKFLLSLAENKLGPCMLLALRGNQTMAEILCLMLEYNIIDNNDTQLQIISTLESTDVGKRMYEQLCDRQRELKELQRKGGPTRLTLPSKSTDADLARLLSSGSFGNLENLSLAFTNVTSACAEHLIKLPSLKQLNLWSTQFGDAGLRLLSEHLTMLQVLNLCETPVTDAGLLALSSMKSLCSLNMNSTKLSADTYEDLKAKLPNLKEVDVRYTEAW", "length": 773 }, "evidence": [ { "id": "F1N6D6", "url": "https://omabrowser.org/oma/group/F1N6D6/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" } ], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 4, "go_terms": [ { "name": "nucleus", "id": "GO:0005634", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005634", "evidence": [ { "database": "UniProtKB", "id": "F1N6D6", "url": "https://www.uniprot.org/uniprotkb/F1N6D6" } ], "pmid": "" }, { "name": "cytoplasm", "id": "GO:0005737", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005737", "evidence": [ { "database": "UniProtKB", "id": "F1N6D6", "url": "https://www.uniprot.org/uniprotkb/F1N6D6" } ], "pmid": "" }, { "name": "nucleoplasm", "id": "GO:0005654", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005654", "evidence": [ { "database": "UniProtKB", "id": "F1N6D6", "url": "https://www.uniprot.org/uniprotkb/F1N6D6" } ], "pmid": "" }, { "name": "cytosol", "id": "GO:0005829", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005829", "evidence": [ { "database": "UniProtKB", "id": "F1N6D6", "url": "https://www.uniprot.org/uniprotkb/F1N6D6" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 233, "end_pos": 235, "annotation": "n_glycosylation_sequon" }, { "start_pos": 597, "end_pos": 599, "annotation": "n_glycosylation_sequon" }, { "start_pos": 616, "end_pos": 618, "annotation": "n_glycosylation_sequon" }, { "start_pos": 683, "end_pos": 685, "annotation": "n_glycosylation_sequon" }, { "start_pos": 690, "end_pos": 692, "annotation": "n_glycosylation_sequon" }, { "start_pos": 760, "end_pos": 762, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "F1N6D6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1N6D6" }, { "id": "PF23066", "database": "Pfam", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF23066" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "C-Maf-inducing protein PH", "eco_id": "ECO_0000259", "start_pos": 68, "end_pos": 186, "start_aa": "Arg", "end_aa": "Leu", "glycosite_overlap": [] } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" }, { "name": "homologset.oma", "label": "OMA Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 233, "end_pos": 235 }, { "start_pos": 597, "end_pos": 599 }, { "start_pos": 616, "end_pos": 618 }, { "start_pos": 683, "end_pos": 685 }, { "start_pos": 690, "end_pos": 692 }, { "start_pos": 760, "end_pos": 762 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ], "tool_support": { "graph_view": "yes" } }, { "uniprot_canonical_ac": "F1N3H5-1", "uniprot_ac": "F1N3H5", "uniprot_id": "F1N3H5_BOVIN", "mass": { "chemical_mass": 395147.0, "monoisotopic_mass": 395147.0 }, "refseq": {}, "gene_names": [ { "name": "CSMD2", "type": "recommended", "evidence": [ { "id": "F1N3H5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1N3H5" } ] } ], "protein_names": [ { "name": "CUB and Sushi multiple domains 2", "type": "synonym", "evidence": [ { "id": "F1N3H5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1N3H5/entry#names_and_taxonomy" } ] } ], "function": [], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Bos taurus", "taxid": 9913, "evidence": [ { "database": "UniProtKB", "id": "F1N3H5", "url": "https://www.uniprot.org/uniprotkb/F1N3H5" } ], "common_name": "Bovine", "glygen_name": "Bovine", "reference_species": "Bos taurus [9913]" } ], "gene": [ { "name": "CSMD2", "url": "https://www.uniprot.org/uniprotkb/F1N3H5", "locus": { "chromosome": "3", "start_pos": 112289188, "end_pos": 111603333, "strand": "-", "evidence": [ { "database": "Ensembl Gene", "id": "ENSBTAG00000005784", "url": "https://www.ensembl.org/id/ENSBTAG00000005784" } ] } } ], "crossref": [ { "id": "ENSBTAG00000005784", "url": "https://bgee.org/?page=gene&gene_id=ENSBTAG00000005784", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "cd00033", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd00033", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "cd00041", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd00041", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "IPR000436", "url": "https://www.ebi.ac.uk/interpro/entry/IPR000436", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR000859", "url": "https://www.ebi.ac.uk/interpro/entry/IPR000859", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR035914", "url": "https://www.ebi.ac.uk/interpro/entry/IPR035914", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR035976", "url": "https://www.ebi.ac.uk/interpro/entry/IPR035976", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR051277", "url": "https://www.ebi.ac.uk/interpro/entry/IPR051277", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "A0A3Q1LIU1", "url": "https://www.orthodb.org/?gene=A0A3Q1LIU1", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A3Q1MUS8", "url": "https://www.orthodb.org/?gene=A0A3Q1MUS8", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "F1N3H5", "url": "https://www.orthodb.org/?gene=F1N3H5", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR45656", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR45656", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR45656:SF6", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR45656:SF6", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00084", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00084", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF00431", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00431", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "A0A3Q1LIU1", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1LIU1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A3Q1LIU1-1", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1LIU1-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A3Q1MUS8", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1MUS8", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A3Q1MUS8-1", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1MUS8-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "F1N3H5", "url": "https://www.uniprot.org/uniprotkb/F1N3H5", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "F1N3H5-1", "url": "https://www.uniprot.org/uniprotkb/F1N3H5-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MPRSRGRELRRCGCPAGRARAEAEISALVPGAGSRWGRQPPPPLTPPPLLLLLGWGLLSASAAAGQNCTFQLQGPNGTVESPGFPYGYPNYANCTWTITAEDQHRIQLVFQSFALEEDFDVLSVFDGPPQPENLRTRLTGFQLPATIVSAATTLSLRLISDYAVSAQGFHASYEVLPSHTCGNPGRLPNGVQQGSTFNLGDKVRYSCNPGFFLEGHAVLTCHAGSENSATWDFPLPSCRADDACGGTLRGQSGIISSPHFPSEYHNNADCTWTILAELGDTIALVFIDFQLEDGYDFLEVTGTEGSSLWFTGASLPAPVISSKNWLRLHFTSDGNHRQRGFSAQYQVKKQIELKSRGVKLMPSKDNSQKTSVLTQVGVSQGHNMCPDPGIPERGKRLGSDFRLGSSVQFTCNEGYDLQGSKRITCMKVSDMFAAWSDHRPVCRARMCDAHLRGPSGIITSPNFPIQYDNNAHCVWIITALNPAKVIKLAFEEFDLERGYDTLTVGDGGQDGDQKTVLYILTGTSVPDLIVSTNHQMWLLFQTDGSGSSLGFKASYEEIEQGSCGDPGVPAYGRREGSRFRHGDTLQFECQPAFELVGQKAITCQKNNQWSAKKPGCVFSCFFNFTSPSGIVLSPNYPEDYGNHLHCVWLILARPESRIHLAFNDIDVEPQFDFLVIKDGATAEAPVLGTFSGNQLPSSITSSGHVARLEFQTDHSTGKRGFNITFTTFRHNECPDPGVPVNGKRFGDSLQLGSSISFLCDEGFLGTQGSETITCVLKEGSVVWNSAVLRCEAPCGGHLTSPSGTILSPGWPGFYKDALSCAWVIEAQPGYPIKITFDRFKTEVNYDTLEVRDGRTYSAPLIGVYHGTQVPQFLISTSNHLYLLFSTDKSHSDIGFQLRYETITLQSDHCLDPGIPVNGQRHGNDFYVGALVTFSCDSGYTLSDGEPLECEPNFQWSRALPSCEALCGGFIQGSSGTILSPGFPDFYPNNLNCTWIIETSHGKGVFFTFHTFHLESGHDYLLITENGSFTQPLRQLTGSRLPAPISAGLYGNFTAQVRFISDFSMSYEGFNITFSEYDLEPCEEPEVPAYSIRKGLQFGVGDTLTFSCFPGYRLEGTARITCLGGRRRLWSSPLPRCVAECGNSVTGTQGTLLSPNFPVNYNNNHECIYSIQTQPGKGIQLKAKAFELSEGDVLKVYDGNNNSARLLGVFSRTELLGVTLNSTSSSLWLDFITDAENTSKGFELHFSSFELIKCEDPGTPQFGYKVHDGGHFAGSSVSFSCDPGYSLRGSEELLCLSGERRAWDRPLPTCVAECGGTVRGEVSGQVLSPGYPAPYEHNLNCVWTIEADAGCTIGLHFLVFDTEEVHDVLRIWDGPVESGVLLKELSGPALPKDLHSTFNSVVLQFSTDFFTSKQGFAIQFSVSTATSCNDPGVPQNGSRSGDSWEAGDSTVFQCDPGYALQGSAEISCVKIENRFFWQPSPPTCIAPCGGDLTGPSGVILSPNYPEPYPPGKECDWKVTVSPDYVIALVFNIFNLEPGYDFLHIYDGRDSLSPLIGSFYGSQLPGRIESSSNSLFLAFRSDASVSNTGFVIDYTENPRESCFDPGSIKNGTRVGSDLKLGSSITYYCHGGYEVEGSSTLSCILGPDGKPVWNHPRPVCTAPCGGQYVGSDGVVLSPNYPQNYTSGQICLYFVTVPKDYVVFGQFAFFHTALNDVVEVHDGHNQHSRLLSSLSGSHTGESLPLATSNQVLVKFSAKGQVPARGFHFVYQAVPRTSATQCSSVPEPRYGRRLGSDFSVGAIVRFECNSGYALQGSPEIECLPVPGALAQWNVSAPTCVVPCGGNLTERRGTILSPGFPEPYLNSLNCVWKIMVPEGAGIQIQVVSFVTEQNWDSLEVFDGADNTVTMLGSFSGTTVPALLNSTSNQLYLHFYSDISVSAAGFHLEYKTVGLSSCPEPAVPSNGVKTGERYLVNDVVSFQCEPGYALQGHAHISCMPGTVRRWNYPPPLCIAQCGGTVEDMEGVILSPGFPGNYPSNMDCSWKIALPVGFGAHIQFLNFSTEPNHDFIEIRNGPYETSRMMGRFSGSELPSALLSTSHETTVYFHSDHSQNRPGFKLEYQAYELQECPDPEPFANGIVRGAGYNVGQSVTFECLPGYQLMGHPVLTCQHGTNRNWDHPLPRCEVPCGSNITSFNGTVYSPGFPSPYSSSQDCIWLITVPIGHGVRLNLSLLQTEPSGDFITVWDGPQKTAPQLGAFSRSFAKKTMYSSSNQVLLQFHHESAMGGIFAIAFSAYPLTKCPPPTILPNAEVVTENEEFNIGDIVRYRCLPGFTLVGNEILTCKLGTYLQFEGPPPICEVHCPTNELLTDSTGVILSQSYPGSYPQFQICSWLVRVEPEYNISITVEYFLSEKQYDEFEIFDGPSGQSPLLKALSGNYSAPLVVTSSSNSVYLRWSSDHAYNRKGFKIRYSAPYCSLPRAPLHGFLLGQTSTQPGGSIHFGCNAGYRLVGHSMAICTRHPQGYHLWSEAIPLCQALSCGLPEAPKNGMVFGKEYTVGTKAVYSCSEGYHLQAGAEATTECLETGLWSNRNVPPQCVPVTCPDISSVSVEHGRWRLIFETQYQFQAQLMLICDPGYYYTGQRVIHCQANGKWSLDNSMPTCQIISCGELPVPPNGHRIGTLSVYGATAIFSCNSGYTLVGSRVRECMANGLWSGSEVRCLAPPTKPPLIFCMLPCNLLSFPHLTKAGHCGTPEPIVNGHINGENFSYRGSVVYQCNAGFRLIGMSVRICQQDHHWSGKTPFCVPITCGHPGNPINGLTQGSQFNLNDVVKFVCNPGYVAEGAARSQCLASGQWSDVLPTCRIINCTDPGHQENSVRQIHASGPHRFSYGTTVSYQCTHGFYLLGTPVLSCQGDGTWDRPRPQCLLVSCGHPGSPPHSQMSGDSYTVGAVVRYSCTGKRTLVGNATRMCGLGGHWTGSLPHCSGTSIGVCGDPGIPAHGIRLGDSFAPGSLMRFSCEAGHVLRGSSERTCQANGLWSGVQPECGVISCGNPGTPSNARVLFSDGLVFSSSIVYECREGYYATGLLSRHCSVNGTWTGSDPECTVINCGDPGVPANGLRLGSDFRYNRTVTYQCVPGYTMESHRVSVLSCTKDRTWNGTKPVCKAIMCKPPQLIPNGKVVGSDFMWGSSVTYACLEGYQLSLPAVLTCEGNGSWTGELPQCFPVFCGDPGVPARGRREDRGFSYRSSVSFSCQPPLVLVGSPRRFCQSDGTWSGTQPSCIDPTLTTCVDPGVPQFGIQNNSQGYQVGSTVLFRCQKGYLLQGSTSRTCLPNLTWSGTPPDCVPHHCKQPETPSHANVGALDLPSMGYTLIYSCQEGFSLKGGSEHRTCKADGSWTGKPPICLEVRPSGRPINTAREPPLTQASVPGDVFAKNSLWKGAYEYQGKKQPAMLRVTGFQVINSKVNATMVDHSGVELHLSGTCKREDFHLLLQVYQITGPVEIFVNKFKDDHWALDGHVSSESSGGTFVYQGSVKGQGFGQFGFQRLDLRLLESDPESIGRHFASNSSSVAAAILVPFIALIIAGFVLYLYKHRRRPKVPFNGYAGHENTNVRATFENPMYDRNIQPTDIMATEAEFTVSTVCTAV", "length": 3633, "header": "tr|F1N3H5-1|F1N3H5_BOVIN Isoform 1 of CUB and Sushi multiple domains 2 OS=Bos taurus OX=9913 GN=CSMD2 PE=3 SV=4 CANONICAL=F1N3H5-1" }, "isoforms": [ { "isoform_ac": "A0A3Q1LIU1-1", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1LIU1/entry", "sequence": { "sequence": "MGLLSIAPRPRFQVQSRHPRSARQNCTFQLQGPNGTVESPGFPYGYPNYANCTWTITAEDQHRIQLVFQSFALEEDFDVLSVFDGPPQPENLRTRLTGFQLPATIVSAATTLSLRLISDYAVSAQGFHASYEVLPSHTCGNPGRLPNGVQQGSTFNLGDKVRYSCNPGFFLEGHAVLTCHAGSENSATWDFPLPSCRADDACGGTLRGQSGIISSPHFPSEYHNNADCTWTILAELGDTIALVFIDFQLEDGYDFLEVTGTEGSSLWFTGASLPAPVISSKNWLRLHFTSDGNHRQRGFSAQYQVKKQIELKSRGVKLMPSKDNSQKTSVLTQVGVSQGHNMCPDPGIPERGKRLGSDFRLGSSVQFTCNEGYDLQGSKRITCMKVSDMFAAWSDHRPVCRARMCDAHLRGPSGIITSPNFPIQYDNNAHCVWIITALNPAKVIKLAFEEFDLERGYDTLTVGDGGQDGDQKTVLYILTGTSVPDLIVSTNHQMWLLFQTDGSGSSLGFKASYEEIEQGSCGDPGVPAYGRREGSRFRHGDTLQFECQPAFELVGQKAITCQKNNQWSAKKPGCVFSCFFNFTSPSGIVLSPNYPEDYGNHLHCVWLILARPESRIHLAFNDIDVEPQFDFLVIKDGATAEAPVLGTFSGNQLPSSITSSGHVARLEFQTDHSTGKRGFNITFTTFRHNECPDPGVPVNGKRFGDSLQLGSSISFLCDEGFLGTQGSETITCVLKEGSVVWNSAVLRCEAPCGGHLTSPSGTILSPGWPGFYKDALSCAWVIEAQPGYPIKITFDRFKTEVNYDTLEVRDGRTYSAPLIGVYHGTQVPQFLISTSNHLYLLFSTDKSHSDIGFQLRYETITLQSDHCLDPGIPVNGQRHGNDFYVGALVTFSCDSGYTLSDGEPLECEPNFQWSRALPSCEALCGGFIQGSSGTILSPGFPDFYPNNLNCTWIIETSHGKGVFFTFHTFHLESGHDYLLITENGSFTQPLRQLTGSRLPAPISAGLYGNFTAQVRFISDFSMSYEGFNITFSEYDLEPCEEPEVPAYSIRKGLQFGVGDTLTFSCFPGYRLEGTARITCLGGRRRLWSSPLPRCVAECGNSVTGTQGTLLSPNFPVNYNNNHECIYSIQTQPGKGIQLKAKAFELSEGDVLKVYDGNNNSARLLGVFSRTELLGVTLNSTSSSLWLDFITDAENTSKGFELHFSSFELIKCEDPGTPQFGYKVHDGGHFAGSSVSFSCDPGYSLRGSEELLCLSGERRAWDRPLPTCVAECGGTVRGEVSGQVLSPGYPAPYEHNLNCVWTIEADAGCTIGLHFLVFDTEEVHDVLRIWDGPVESGVLLKELSGPALPKDLHSTFNSVVLQFSTDFFTSKQGFAIQFSVSTATSCNDPGVPQNGSRSGDSWEAGDSTVFQCDPGYALQGSAEISCVKIENRFFWQPSPPTCIAPCGGDLTGPSGVILSPNYPEPYPPGKECDWKVTVSPDYVIALVFNIFNLEPGYDFLHIYDGRDSLSPLIGSFYGSQLPGRIESSSNSLFLAFRSDASVSNTGFVIDYTENPRESCFDPGSIKNGTRVGSDLKLGSSITYYCHGGYEVEGSSTLSCILGPDGKPVWNHPRPVCTAPCGGQYVGSDGVVLSPNYPQNYTSGQICLYFVTVPKDYVVFGQFAFFHTALNDVVEVHDGHNQHSRLLSSLSGSHTGESLPLATSNQVLVKFSAKGQVPARGFHFVYQAVPRTSATQCSSVPEPRYGRRLGSDFSVGAIVRFECNSGYALQGSPEIECLPVPGALAQWNVSAPTCVVPCGGNLTERRGTILSPGFPEPYLNSLNCVWKIMVPEGAGIQIQVVSFVTEQNWDSLEVFDGADNTVTMLGSFSGTTVPALLNSTSNQLYLHFYSDISVSAAGFHLEYKTVGLSSCPEPAVPSNGVKTGERYLVNDVVSFQCEPGYALQGHAHISCMPGTVRRWNYPPPLCIAQCGGTVEDMEGVILSPGFPGNYPSNMDCSWKIALPVGFGAHIQFLNFSTEPNHDFIEIRNGPYETSRMMGRFSGSELPSALLSTSHETTVYFHSDHSQNRPGFKLEYQAYELQECPDPEPFANGIVRGAGYNVGQSVTFECLPGYQLMGHPVLTCQHGTNRNWDHPLPRCEVPCGSNITSFNGTVYSPGFPSPYSSSQDCIWLITVPIGHGVRLNLSLLQTEPSGDFITVWDGPQKTAPQLGAFSRSFAKKTMYSSSNQVLLQFHHESAMGGIFAIAFSAYPLTKCPPPTILPNAEVVTENEEFNIGDIVRYRCLPGFTLVGNEILTCKLGTYLQFEGPPPICEVHCPTNELLTDSTGVILSQSYPGSYPQFQICSWLVRVEPEYNISITVEYFLSEKQYDEFEIFDGPSGQSPLLKALSGNYSAPLVVTSSSNSVYLRWSSDHAYNRKGFKIRYSAPYCSLPRAPLHGFLLGQTSTQPGGSIHFGCNAGYRLVGHSMAICTRHPQGYHLWSEAIPLCQALSCGLPEAPKNGMVFGKEYTVGTKAVYSCSEGYHLQAGAEATTECLETGLWSNRNVPPQCVPVTCPDISSVSVEHGRWRLIFETQYQFQAQLMLICDPGYYYTGQRVIHCQANGKWSLDNSMPTCQIISCGELPVPPNGHRIGTLSVYGATAIFSCNSGYTLVGSRVRECMANGLWSGSEVRCLAPPTKPPLIFCMLPCNLLSFPHLTKAGHCGTPEPIVNGHINGENFSYRGSVVYQCNAGFRLIGMSVRICQQDHHWSGKTPFCVPITCGHPGNPINGLTQGSQFNLNDVVKFVCNPGYVAEGAARSQCLASGQWSDVLPTCRIINCTDPGHQENSVRQIHASGPHRFSYGTTVSYQCTHGFYLLGTPVLSCQGDGTWDRPRPQCLLVSCGHPGSPPHSQMSGDSYTVGAVVRYSCTGKRTLVGNATRMCGLGGHWTGSLPHCSGTSIGVCGDPGIPAHGIRLGDSFAPGSLMRFSCEAGHVLRGSSERTCQANGLWSGVQPECGVISCGNPGTPSNARVLFSDGLVFSSSIVYECREGYYATGLLSRHCSVNGTWTGSDPECTVINCGDPGVPANGLRLGSDFRYNRTVTYQCVPGYTMESHRVSVLSCTKDRTWNGTKPVCKAIMCKPPQLIPNGKVVGSDFMWGSSVTYACLEGYQLSLPAVLTCEGNGSWTGELPQCFPVFCGDPGVPARGRREDRGFSYRSSVSFSCQPPLVLVGSPRRFCQSDGTWSGTQPSCIDPTLTTCVDPGVPQFGIQNNSQGYQVGSTVLFRCQKGYLLQGSTSRTCLPNLTWSGTPPDCVPHHCKQPETPSHANVGALDLPSMGYTLIYSCQEGFSLKGGSEHRTCKADGSWTGKPPICLEVRPSGRPINTAREPPLTQASVPGDVFAKNSLWKGAYEYQGKKQPAMLRVTGFQVINSKVNATMVDHSGVELHLSGTCKREDFHLLLQVYQITGPVEIFVNKFKDDHWALDGHVSSESSGGTFVYQGSVKGQGFGQFGFQRLDLRLLESDPESIGRHFASNSSSVAAAILVPFIALIIAGFVLYLYKHRRRPKVPFNGYAGHENTNVRATFENPMYDRNIQPTDIMATEAEFTVSTVCTAV", "length": 3591, "header": "tr|A0A3Q1LIU1-1|F1N3H5_BOVIN Computationally mapped isoform of CUB and Sushi multiple domains 2 OS=Bos taurus OX=9913 GN=CSMD2 PE=3 SV=2 CANONICAL=F1N3H5-1" }, "locus": { "chromosome": "3", "start_pos": 112289185, "end_pos": 111603333, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000067968.2", "url": "https://www.ensembl.org/id/ENSBTAT00000067968.2" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000059092.2", "url": "https://www.ensembl.org/id/ENSBTAP00000059092.2" } ] } }, { "isoform_ac": "A0A3Q1MUS8-1", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1MUS8/entry", "sequence": { "sequence": "MGLLSIAPRPRFQVQSRHPRSARQNCTFQLQGPNGTVESPGFPYGYPNYANCTWTITAEDQHRIQLVFQSFALEEDFDVLSVFDGPPQPENLRTRLTGFQLPATIVSAATTLSLRLISDYAVSAQGFHASYEVLPSHTCGNPGRLPNGVQQGSTFNLGDKVRYSCNPGFFLEGHAVLTCHAGSENSATWDFPLPSCRADDACGGTLRGQSGIISSPHFPSEYHNNADCTWTILAELGDTIALVFIDFQLEDGYDFLEVTGTEGSSLWFTGASLPAPVISSKNWLRLHFTSDGNHRQRGFSAQYQVKKQIELKSRGVKLMPSKDNSQKTSVLTQVGVSQGHNMCPDPGIPERGKRLGSDFRLGSSVQFTCNEGYDLQGSKRITCMKVSDMFAAWSDHRPVCRARMCDAHLRGPSGIITSPNFPIQYDNNAHCVWIITALNPAKVIKLAFEEFDLERGYDTLTVGDGGQDGDQKTVLYILTGTSVPDLIVSTNHQMWLLFQTDGSGSSLGFKASYEEIEQGSCGDPGVPAYGRREGSRFRHGDTLQFECQPAFELVGQKAITCQKNNQWSAKKPGCVFSCFFNFTSPSGIVLSPNYPEDYGNHLHCVWLILARPESRIHLAFNDIDVEPQFDFLVIKDGATAEAPVLGTFSGNQLPSSITSSGHVARLEFQTDHSTGKRGFNITFTTFRHNECPDPGVPVNGKRFGDSLQLGSSISFLCDEGFLGTQGSETITCVLKEGSVVWNSAVLRCEAPCGGHLTSPSGTILSPGWPGFYKDALSCAWVIEAQPGYPIKITFDRFKTEVNYDTLEVRDGRTYSAPLIGVYHGTQVPQFLISTSNHLYLLFSTDKSHSDIGFQLRYETITLQSDHCLDPGIPVNGQRHGNDFYVGALVTFSCDSGYTLSDGEPLECEPNFQWSRALPSCEALCGGFIQGSSGTILSPGFPDFYPNNLNCTWIIETSHGKGVFFTFHTFHLESGHDYLLITENGSFTQPLRQLTGSRLPAPISAGLYGNFTAQVRFISDFSMSYEGFNITFSEYDLEPCEEPEVPAYSIRKGLQFGVGDTLTFSCFPGYRLEGTARITCLGGRRRLWSSPLPRCVAECGNSVTGTQGTLLSPNFPVNYNNNHECIYSIQTQPGKGIQLKAKAFELSEGDVLKVYDGNNNSARLLGVFSRTELLGVTLNSTSSSLWLDFITDAENTSKGFELHFSSFELIKCEDPGTPQFGYKVHDGGHFAGSSVSFSCDPGYSLRGSEELLCLSGERRAWDRPLPTCVAECGGTVRGEVSGQVLSPGYPAPYEHNLNCVWTIEADAGCTIGLHFLVFDTEEVHDVLRIWDGPVESGVLLKELSGPALPKDLHSTFNSVVLQFSTDFFTSKQGFAIQFSVSTATSCNDPGVPQNGSRSGDSWEAGDSTVFQCDPGYALQGSAEISCVKIENRFFWQPSPPTCIAPCGGDLTGPSGVILSPNYPEPYPPGKECDWKVTVSPDYVIALVFNIFNLEPGYDFLHIYDGRDSLSPLIGSFYGSQLPGRIESSSNSLFLAFRSDASVSNTGFVIDYTENPRESCFDPGSIKNGTRVGSDLKLGSSITYYCHGGYEVEGSSTLSCILGPDGKPVWNHPRPVCTAPCGGQYVGSDGVVLSPNYPQNYTSGQICLYFVTVPKDYVVFGQFAFFHTALNDVVEVHDGHNQHSRLLSSLSGSHTGESLPLATSNQVLVKFSAKGQVPARGFHFVYQAVPRTSATQCSSVPEPRYGRRLGSDFSVGAIVRFECNSGYALQGSPEIECLPVPGALAQWNVSAPTCVVPCGGNLTERRGTILSPGFPEPYLNSLNCVWKIMVPEGAGIQIQVVSFVTEQNWDSLEVFDGADNTVTMLGSFSGTTVPALLNSTSNQLYLHFYSDISVSAAGFHLEYKTVGLSSCPEPAVPSNGVKTGERYLVNDVVSFQCEPGYALQGHAHISCMPGTVRRWNYPPPLCIAQCGGTVEDMEGVILSPGFPGNYPSNMDCSWKIALPVGFGAHIQFLNFSTEPNHDFIEIRNGPYETSRMMGRFSGSELPSALLSTSHETTVYFHSDHSQNRPGFKLEYQWAYSLVSSFLRGSNCSESEGPHSSAHLTASCVCDLGGYWAYELQECPDPEPFANGIVRGAGYNVGQSVTFECLPGYQLMGHPVLTCQHGTNRNWDHPLPRCEVPCGSNITSFNGTVYSPGFPSPYSSSQDCIWLITVPIGHGVRLNLSLLQTEPSGDFITVWDGPQKTAPQLGAFSRSFAKKTMYSSSNQVLLQFHHESAMGGIFAIAFSAYPLTKCPPPTILPNAEVVTENEEFNIGDIVRYRCLPGFTLVGNEILTCKLGTYLQFEGPPPICEVHCPTNELLTDSTGVILSQSYPGSYPQFQICSWLVRVEPEYNISITVEYFLSEKQYDEFEIFDGPSGQSPLLKALSGNYSAPLVVTSSSNSVYLRWSSDHAYNRKGFKIRYSAPYCSLPRAPLHGFLLGQTSTQPGGSIHFGCNAGYRLVGHSMAICTRHPQGYHLWSEAIPLCQALSCGLPEAPKNGMVFGKEYTVGTKAVYSCSEGYHLQAGAEATTECLETGLWSNRNVPPQCVPVTCPDISSVSVEHGRWRLIFETQYQFQAQLMLICDPGYYYTGQRVIHCQANGKWSLDNSMPTCQIISCGELPVPPNGHRIGTLSVYGATAIFSCNSGYTLVGSRVRECMANGLWSGSEVRCLAGHCGTPEPIVNGHINGENFSYRGSVVYQCNAGFRLIGMSVRICQQDHHWSGKTPFCVLVSCGHPGSPPHSQMSGDSYTVGAVVRYSCTGKRTLVGNATRMCGLGGHWTGSLPHCSGTSIGVCGDPGIPAHGIRLGDSFAPGSLMRFSCEAGHVLRGSSERTCQANGLWSGVQPECGVISCGNPGTPSNARVLFSDGLVFSSSIVYECREGYYATGLLSRHCSVNGTWTGSDPECTVINCGDPGVPANGLRLGSDFRYNRTVTYQCVPGYTMESHRVSVLSCTKDRTWNGTKPVCKAIMCKPPQLIPNGKVVGSDFMWGSSVTYACLEGYQLSLPAVLTCEGNGSWTGELPQCFPVFCGDPGVPARGRREDRGFSYRSSVSFSCQPPLVLVGSPRRFCQSDGTWSGTQPSCIDPTLTTCVDPGVPQFGIQNNSQGYQVGSTVLFRCQKGYLLQGSTSRTCLPNLTWSGTPPDCVPHHCKQPETPSHANVGALDLPSMGYTLIYSCQEGFSLKGGSEHRTCKADGSWTGKPPICLEVRPSGRPINTAREPPLTQASVPGDVFAKNSLWKGAYEYQGKKQPAMLRVTGFQVINSKVNATMVDHSGVELHLSGTCKREDFHLLLQVYQITGPVEIFVNKFKDDHWALDGHVSSESSGGTFVYQGSVKGQGFGQFGFQRLDLRLLESDPESIGRHFASNSSSVAAAILVPFIALIIAGFVLYLYKHRRRPKVPFNGYAGHENTNVRATFENPMYDRNIQPTDIMATEAEFTVSTVCTAV", "length": 3484, "header": "tr|A0A3Q1MUS8-1|F1N3H5_BOVIN Computationally mapped isoform of CUB and Sushi multiple domains 2 OS=Bos taurus OX=9913 GN=CSMD2 PE=3 SV=2 CANONICAL=F1N3H5-1" }, "locus": { "chromosome": "3", "start_pos": 112289185, "end_pos": 111603333, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000081868.2", "url": "https://www.ensembl.org/id/ENSBTAT00000081868.2" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000074409.2", "url": "https://www.ensembl.org/id/ENSBTAP00000074409.2" } ] } }, { "isoform_ac": "F1N3H5-1", "url": "https://www.uniprot.org/uniprotkb/F1N3H5/entry", "sequence": { "sequence": "MPRSRGRELRRCGCPAGRARAEAEISALVPGAGSRWGRQPPPPLTPPPLLLLLGWGLLSASAAAGQNCTFQLQGPNGTVESPGFPYGYPNYANCTWTITAEDQHRIQLVFQSFALEEDFDVLSVFDGPPQPENLRTRLTGFQLPATIVSAATTLSLRLISDYAVSAQGFHASYEVLPSHTCGNPGRLPNGVQQGSTFNLGDKVRYSCNPGFFLEGHAVLTCHAGSENSATWDFPLPSCRADDACGGTLRGQSGIISSPHFPSEYHNNADCTWTILAELGDTIALVFIDFQLEDGYDFLEVTGTEGSSLWFTGASLPAPVISSKNWLRLHFTSDGNHRQRGFSAQYQVKKQIELKSRGVKLMPSKDNSQKTSVLTQVGVSQGHNMCPDPGIPERGKRLGSDFRLGSSVQFTCNEGYDLQGSKRITCMKVSDMFAAWSDHRPVCRARMCDAHLRGPSGIITSPNFPIQYDNNAHCVWIITALNPAKVIKLAFEEFDLERGYDTLTVGDGGQDGDQKTVLYILTGTSVPDLIVSTNHQMWLLFQTDGSGSSLGFKASYEEIEQGSCGDPGVPAYGRREGSRFRHGDTLQFECQPAFELVGQKAITCQKNNQWSAKKPGCVFSCFFNFTSPSGIVLSPNYPEDYGNHLHCVWLILARPESRIHLAFNDIDVEPQFDFLVIKDGATAEAPVLGTFSGNQLPSSITSSGHVARLEFQTDHSTGKRGFNITFTTFRHNECPDPGVPVNGKRFGDSLQLGSSISFLCDEGFLGTQGSETITCVLKEGSVVWNSAVLRCEAPCGGHLTSPSGTILSPGWPGFYKDALSCAWVIEAQPGYPIKITFDRFKTEVNYDTLEVRDGRTYSAPLIGVYHGTQVPQFLISTSNHLYLLFSTDKSHSDIGFQLRYETITLQSDHCLDPGIPVNGQRHGNDFYVGALVTFSCDSGYTLSDGEPLECEPNFQWSRALPSCEALCGGFIQGSSGTILSPGFPDFYPNNLNCTWIIETSHGKGVFFTFHTFHLESGHDYLLITENGSFTQPLRQLTGSRLPAPISAGLYGNFTAQVRFISDFSMSYEGFNITFSEYDLEPCEEPEVPAYSIRKGLQFGVGDTLTFSCFPGYRLEGTARITCLGGRRRLWSSPLPRCVAECGNSVTGTQGTLLSPNFPVNYNNNHECIYSIQTQPGKGIQLKAKAFELSEGDVLKVYDGNNNSARLLGVFSRTELLGVTLNSTSSSLWLDFITDAENTSKGFELHFSSFELIKCEDPGTPQFGYKVHDGGHFAGSSVSFSCDPGYSLRGSEELLCLSGERRAWDRPLPTCVAECGGTVRGEVSGQVLSPGYPAPYEHNLNCVWTIEADAGCTIGLHFLVFDTEEVHDVLRIWDGPVESGVLLKELSGPALPKDLHSTFNSVVLQFSTDFFTSKQGFAIQFSVSTATSCNDPGVPQNGSRSGDSWEAGDSTVFQCDPGYALQGSAEISCVKIENRFFWQPSPPTCIAPCGGDLTGPSGVILSPNYPEPYPPGKECDWKVTVSPDYVIALVFNIFNLEPGYDFLHIYDGRDSLSPLIGSFYGSQLPGRIESSSNSLFLAFRSDASVSNTGFVIDYTENPRESCFDPGSIKNGTRVGSDLKLGSSITYYCHGGYEVEGSSTLSCILGPDGKPVWNHPRPVCTAPCGGQYVGSDGVVLSPNYPQNYTSGQICLYFVTVPKDYVVFGQFAFFHTALNDVVEVHDGHNQHSRLLSSLSGSHTGESLPLATSNQVLVKFSAKGQVPARGFHFVYQAVPRTSATQCSSVPEPRYGRRLGSDFSVGAIVRFECNSGYALQGSPEIECLPVPGALAQWNVSAPTCVVPCGGNLTERRGTILSPGFPEPYLNSLNCVWKIMVPEGAGIQIQVVSFVTEQNWDSLEVFDGADNTVTMLGSFSGTTVPALLNSTSNQLYLHFYSDISVSAAGFHLEYKTVGLSSCPEPAVPSNGVKTGERYLVNDVVSFQCEPGYALQGHAHISCMPGTVRRWNYPPPLCIAQCGGTVEDMEGVILSPGFPGNYPSNMDCSWKIALPVGFGAHIQFLNFSTEPNHDFIEIRNGPYETSRMMGRFSGSELPSALLSTSHETTVYFHSDHSQNRPGFKLEYQAYELQECPDPEPFANGIVRGAGYNVGQSVTFECLPGYQLMGHPVLTCQHGTNRNWDHPLPRCEVPCGSNITSFNGTVYSPGFPSPYSSSQDCIWLITVPIGHGVRLNLSLLQTEPSGDFITVWDGPQKTAPQLGAFSRSFAKKTMYSSSNQVLLQFHHESAMGGIFAIAFSAYPLTKCPPPTILPNAEVVTENEEFNIGDIVRYRCLPGFTLVGNEILTCKLGTYLQFEGPPPICEVHCPTNELLTDSTGVILSQSYPGSYPQFQICSWLVRVEPEYNISITVEYFLSEKQYDEFEIFDGPSGQSPLLKALSGNYSAPLVVTSSSNSVYLRWSSDHAYNRKGFKIRYSAPYCSLPRAPLHGFLLGQTSTQPGGSIHFGCNAGYRLVGHSMAICTRHPQGYHLWSEAIPLCQALSCGLPEAPKNGMVFGKEYTVGTKAVYSCSEGYHLQAGAEATTECLETGLWSNRNVPPQCVPVTCPDISSVSVEHGRWRLIFETQYQFQAQLMLICDPGYYYTGQRVIHCQANGKWSLDNSMPTCQIISCGELPVPPNGHRIGTLSVYGATAIFSCNSGYTLVGSRVRECMANGLWSGSEVRCLAPPTKPPLIFCMLPCNLLSFPHLTKAGHCGTPEPIVNGHINGENFSYRGSVVYQCNAGFRLIGMSVRICQQDHHWSGKTPFCVPITCGHPGNPINGLTQGSQFNLNDVVKFVCNPGYVAEGAARSQCLASGQWSDVLPTCRIINCTDPGHQENSVRQIHASGPHRFSYGTTVSYQCTHGFYLLGTPVLSCQGDGTWDRPRPQCLLVSCGHPGSPPHSQMSGDSYTVGAVVRYSCTGKRTLVGNATRMCGLGGHWTGSLPHCSGTSIGVCGDPGIPAHGIRLGDSFAPGSLMRFSCEAGHVLRGSSERTCQANGLWSGVQPECGVISCGNPGTPSNARVLFSDGLVFSSSIVYECREGYYATGLLSRHCSVNGTWTGSDPECTVINCGDPGVPANGLRLGSDFRYNRTVTYQCVPGYTMESHRVSVLSCTKDRTWNGTKPVCKAIMCKPPQLIPNGKVVGSDFMWGSSVTYACLEGYQLSLPAVLTCEGNGSWTGELPQCFPVFCGDPGVPARGRREDRGFSYRSSVSFSCQPPLVLVGSPRRFCQSDGTWSGTQPSCIDPTLTTCVDPGVPQFGIQNNSQGYQVGSTVLFRCQKGYLLQGSTSRTCLPNLTWSGTPPDCVPHHCKQPETPSHANVGALDLPSMGYTLIYSCQEGFSLKGGSEHRTCKADGSWTGKPPICLEVRPSGRPINTAREPPLTQASVPGDVFAKNSLWKGAYEYQGKKQPAMLRVTGFQVINSKVNATMVDHSGVELHLSGTCKREDFHLLLQVYQITGPVEIFVNKFKDDHWALDGHVSSESSGGTFVYQGSVKGQGFGQFGFQRLDLRLLESDPESIGRHFASNSSSVAAAILVPFIALIIAGFVLYLYKHRRRPKVPFNGYAGHENTNVRATFENPMYDRNIQPTDIMATEAEFTVSTVCTAV", "length": 3633, "header": "tr|F1N3H5-1|F1N3H5_BOVIN Isoform 1 of CUB and Sushi multiple domains 2 OS=Bos taurus OX=9913 GN=CSMD2 PE=3 SV=4 CANONICAL=F1N3H5-1" }, "locus": { "chromosome": "3", "start_pos": 112289185, "end_pos": 111604061, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000007609.7", "url": "https://www.ensembl.org/id/ENSBTAT00000007609.7" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000007609.7", "url": "https://www.ensembl.org/id/ENSBTAP00000007609.7" } ] } } ], "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "other", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 3044, "start_aa": "Thr", "end_pos": 3044, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr3044", "evidence": [ { "id": "", "database": "GlyGen", "url": "https://data.glygen.org/" } ], "filter_code": "000000000000000010000.00000000001000.0.01000" } ], "phosphorylation": [], "glycation": [], "keywords": [ "glycoprotein", "glycoprotein_predicted" ], "publication": [], "pathway": [], "orthologs": [], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 3, "go_terms": [ { "name": "membrane", "id": "GO:0016020", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016020", "evidence": [ { "database": "UniProtKB", "id": "F1N3H5", "url": "https://www.uniprot.org/uniprotkb/F1N3H5" } ], "pmid": "" }, { "name": "glutamatergic synapse", "id": "GO:0098978", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0098978", "evidence": [ { "database": "UniProtKB", "id": "F1N3H5", "url": "https://www.uniprot.org/uniprotkb/F1N3H5" } ], "pmid": "" }, { "name": "postsynaptic density membrane", "id": "GO:0098839", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0098839", "evidence": [ { "database": "UniProtKB", "id": "F1N3H5", "url": "https://www.uniprot.org/uniprotkb/F1N3H5" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 2, "go_terms": [ { "name": "postsynaptic density assembly", "id": "GO:0097107", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0097107", "evidence": [ { "database": "UniProtKB", "id": "F1N3H5", "url": "https://www.uniprot.org/uniprotkb/F1N3H5" } ], "pmid": "" }, { "name": "maintenance of postsynaptic density structure", "id": "GO:0099562", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0099562", "evidence": [ { "database": "UniProtKB", "id": "F1N3H5", "url": "https://www.uniprot.org/uniprotkb/F1N3H5" } ], "pmid": "" } ] }, { "name": "Molecular Function", "total": 1, "go_terms": [ { "name": "cargo receptor activity", "id": "GO:0038024", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0038024", "evidence": [ { "database": "UniProtKB", "id": "F1N3H5", "url": "https://www.uniprot.org/uniprotkb/F1N3H5" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 1025, "end_pos": 1027, "annotation": "n_glycosylation_sequon" }, { "start_pos": 1051, "end_pos": 1053, "annotation": "n_glycosylation_sequon" }, { "start_pos": 1070, "end_pos": 1072, "annotation": "n_glycosylation_sequon" }, { "start_pos": 1200, "end_pos": 1202, "annotation": "n_glycosylation_sequon" }, { "start_pos": 1220, "end_pos": 1222, "annotation": "n_glycosylation_sequon" }, { "start_pos": 1236, "end_pos": 1238, "annotation": "n_glycosylation_sequon" }, { "start_pos": 1435, "end_pos": 1437, "annotation": "n_glycosylation_sequon" }, { "start_pos": 1608, "end_pos": 1610, "annotation": "n_glycosylation_sequon" }, { "start_pos": 1680, "end_pos": 1682, "annotation": "n_glycosylation_sequon" }, { "start_pos": 1828, "end_pos": 1830, "annotation": "n_glycosylation_sequon" }, { "start_pos": 1841, "end_pos": 1843, "annotation": "n_glycosylation_sequon" }, { "start_pos": 1918, "end_pos": 1920, "annotation": "n_glycosylation_sequon" }, { "start_pos": 2054, "end_pos": 2056, "annotation": "n_glycosylation_sequon" }, { "start_pos": 2185, "end_pos": 2187, "annotation": "n_glycosylation_sequon" }, { "start_pos": 2190, "end_pos": 2192, "annotation": "n_glycosylation_sequon" }, { "start_pos": 2223, "end_pos": 2225, "annotation": "n_glycosylation_sequon" }, { "start_pos": 2394, "end_pos": 2396, "annotation": "n_glycosylation_sequon" }, { "start_pos": 2430, "end_pos": 2432, "annotation": "n_glycosylation_sequon" }, { "start_pos": 2756, "end_pos": 2758, "annotation": "n_glycosylation_sequon" }, { "start_pos": 2856, "end_pos": 2858, "annotation": "n_glycosylation_sequon" }, { "start_pos": 2955, "end_pos": 2957, "annotation": "n_glycosylation_sequon" }, { "start_pos": 3083, "end_pos": 3085, "annotation": "n_glycosylation_sequon" }, { "start_pos": 3117, "end_pos": 3119, "annotation": "n_glycosylation_sequon" }, { "start_pos": 3147, "end_pos": 3149, "annotation": "n_glycosylation_sequon" }, { "start_pos": 3201, "end_pos": 3203, "annotation": "n_glycosylation_sequon" }, { "start_pos": 3289, "end_pos": 3291, "annotation": "n_glycosylation_sequon" }, { "start_pos": 3321, "end_pos": 3323, "annotation": "n_glycosylation_sequon" }, { "start_pos": 3453, "end_pos": 3455, "annotation": "n_glycosylation_sequon" }, { "start_pos": 3553, "end_pos": 3555, "annotation": "n_glycosylation_sequon" }, { "start_pos": 623, "end_pos": 625, "annotation": "n_glycosylation_sequon" }, { "start_pos": 67, "end_pos": 69, "annotation": "n_glycosylation_sequon" }, { "start_pos": 722, "end_pos": 724, "annotation": "n_glycosylation_sequon" }, { "start_pos": 76, "end_pos": 78, "annotation": "n_glycosylation_sequon" }, { "start_pos": 93, "end_pos": 95, "annotation": "n_glycosylation_sequon" }, { "start_pos": 991, "end_pos": 993, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "F1N3H5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1N3H5" }, { "id": "PS01180", "database": "PROSITE", "url": "https://prosite.expasy.org/PS01180" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "CUB", "eco_id": "ECO_0000259", "start_pos": 68, "end_pos": 176, "start_aa": "Cys", "end_aa": "Leu", "glycosite_overlap": [] }, { "evidence": [ { "id": "F1N3H5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1N3H5" }, { "id": "PS50923", "database": "PROSITE", "url": "https://prosite.expasy.org/PS50923" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "Sushi", "eco_id": "ECO_0000259", "start_pos": 179, "end_pos": 240, "start_aa": "His", "end_aa": "Ala", "glycosite_overlap": [] } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [ 3044 ], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 1025, "end_pos": 1027 }, { "start_pos": 1051, "end_pos": 1053 }, { "start_pos": 1070, "end_pos": 1072 }, { "start_pos": 1200, "end_pos": 1202 }, { "start_pos": 1220, "end_pos": 1222 }, { "start_pos": 1236, "end_pos": 1238 }, { "start_pos": 1435, "end_pos": 1437 }, { "start_pos": 1608, "end_pos": 1610 }, { "start_pos": 1680, "end_pos": 1682 }, { "start_pos": 1828, "end_pos": 1830 }, { "start_pos": 1841, "end_pos": 1843 }, { "start_pos": 1918, "end_pos": 1920 }, { "start_pos": 2054, "end_pos": 2056 }, { "start_pos": 2185, "end_pos": 2187 }, { "start_pos": 2190, "end_pos": 2192 }, { "start_pos": 2223, "end_pos": 2225 }, { "start_pos": 2394, "end_pos": 2396 }, { "start_pos": 2430, "end_pos": 2432 }, { "start_pos": 2756, "end_pos": 2758 }, { "start_pos": 2856, "end_pos": 2858 }, { "start_pos": 2955, "end_pos": 2957 }, { "start_pos": 3083, "end_pos": 3085 }, { "start_pos": 3117, "end_pos": 3119 }, { "start_pos": 3147, "end_pos": 3149 }, { "start_pos": 3201, "end_pos": 3203 }, { "start_pos": 3289, "end_pos": 3291 }, { "start_pos": 3321, "end_pos": 3323 }, { "start_pos": 3453, "end_pos": 3455 }, { "start_pos": 3553, "end_pos": 3555 }, { "start_pos": 623, "end_pos": 625 }, { "start_pos": 67, "end_pos": 69 }, { "start_pos": 722, "end_pos": 724 }, { "start_pos": 76, "end_pos": 78 }, { "start_pos": 93, "end_pos": 95 }, { "start_pos": 991, "end_pos": 993 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 1 }, { "field": "total_sites", "count": 1 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 1 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "exact_sites", "count": 1 }, { "field": "exact_o_linked_sites", "count": 1 }, { "field": "fuzzy_sites", "count": 0 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_pos", "start_aa", "end_pos", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 1 }, { "field": "total_sites", "count": 1 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 1 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "exact_sites", "count": 1 }, { "field": "exact_o_linked_sites", "count": 1 }, { "field": "fuzzy_sites", "count": 0 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_pos", "start_aa", "end_pos", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ], "tool_support": { "graph_view": "yes" } }, { "uniprot_canonical_ac": "F6QT33-1", "uniprot_ac": "F6QT33", "uniprot_id": "F6QT33_BOVIN", "mass": { "chemical_mass": 48077.0, "monoisotopic_mass": 48077.0 }, "refseq": { "ac": "NP_001103552", "name": "RNA-binding protein 34", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001103552" }, "gene_names": [ { "name": "RBM34", "type": "recommended", "evidence": [ { "id": "F6QT33", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F6QT33" } ] }, { "name": "RBM34", "type": "synonym", "evidence": [ { "id": "NP_001103552", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001103552" } ] } ], "protein_names": [ { "name": "RNA-binding protein 34", "type": "recommended", "evidence": [ { "id": "F6QT33", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F6QT33/entry#names_and_taxonomy" } ] }, { "name": "RNA-binding motif protein 34", "type": "synonym", "evidence": [ { "id": "F6QT33", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F6QT33/entry#names_and_taxonomy" } ] }, { "name": "RNA-binding protein 34", "type": "synonym", "evidence": [ { "id": "NP_001103552", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001103552" } ] } ], "function": [], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Bos taurus", "taxid": 9913, "evidence": [ { "database": "UniProtKB", "id": "F6QT33", "url": "https://www.uniprot.org/uniprotkb/F6QT33" } ], "common_name": "Bovine", "glygen_name": "Bovine", "reference_species": "Bos taurus [9913]" } ], "gene": [ { "name": "RBM34", "url": "https://www.uniprot.org/uniprotkb/F6QT33", "locus": { "chromosome": "28", "start_pos": 7903197, "end_pos": 7922488, "strand": "+", "evidence": [ { "database": "Ensembl Gene", "id": "ENSBTAG00000000221", "url": "https://www.ensembl.org/id/ENSBTAG00000000221" } ] } } ], "crossref": [ { "id": "F6QT33", "url": "https://alphafold.ebi.ac.uk/entry/F6QT33", "database": "AlphaFoldDB", "categories": [] }, { "id": "ENSBTAG00000000221", "url": "https://bgee.org/?page=gene&gene_id=ENSBTAG00000000221", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "cd12394", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd12394", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "cd12395", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd12395", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "537542", "url": "https://www.ncbi.nlm.nih.gov/gene/537542", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR000504", "url": "https://www.ebi.ac.uk/interpro/entry/IPR000504", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR012677", "url": "https://www.ebi.ac.uk/interpro/entry/IPR012677", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR034221", "url": "https://www.ebi.ac.uk/interpro/entry/IPR034221", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR035979", "url": "https://www.ebi.ac.uk/interpro/entry/IPR035979", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "bta:537542", "url": "https://www.genome.jp/dbget-bin/www_bget?bta:537542", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "CAVPKKG", "url": "https://omabrowser.org/oma/group/CAVPKKG/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "F6QT33", "url": "https://www.orthodb.org/?gene=F6QT33", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR23236", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR23236", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR23236:SF25", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR23236:SF25", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00076", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00076", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "NP_001103552", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001103552", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A3Q1LKV5", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1LKV5", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A3Q1LKV5-1", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1LKV5-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A3Q1MML7", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1MML7", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A3Q1MML7-1", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1MML7-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0AAA9SBR8", "url": "https://www.uniprot.org/uniprotkb/A0AAA9SBR8", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0AAA9SBR8-1", "url": "https://www.uniprot.org/uniprotkb/A0AAA9SBR8-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "F6QT33", "url": "https://www.uniprot.org/uniprotkb/F6QT33", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "F6QT33-1", "url": "https://www.uniprot.org/uniprotkb/F6QT33-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MALEGKNKREKKQSAQEGQNPDDGACGNLEGDYEVGQVANSLFRGKQPSRGSTGRLASLFGSVNPQLQPVYVPVPEEAIKKRKRDEEEESSPQIQRPLLQEPAKKMKVKKKLSDAEKKLANREDALASADLEEEIHQKQGQKRKNSQPGVTVADKELLDDVEETVVNQRKKIQINQEEERLKNERTVFVGNLPVTCNKKKLKSFFKEYGQIESVRFRSLIPAEGTLSKKLAAIKRKIHPDQKNINAYVVFKDESAATKALERNGAQFAEGFRVRVDLATETSSRDKRSVFVGNLPYKVEESAVEKHFLACGNVVAVRIVRDQVTGVGRGFGYVLFENTDAVHLALKLNNSELMGRKLRVMRSVHKEKLKQNSNLSLKNVSKPKQGLNFASKSAQNSKGLFIGEKAVLMKKKKKGQKKSRRTKTQKKQK", "length": 428, "header": "tr|F6QT33-1|F6QT33_BOVIN Isoform 1 of RNA-binding protein 34 OS=Bos taurus OX=9913 GN=RBM34 PE=3 SV=1 CANONICAL=F6QT33-1" }, "isoforms": [ { "isoform_ac": "A0A3Q1LKV5-1", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1LKV5/entry", "sequence": { "sequence": "MALEGKNKREKKQSAQEGQNPDDGACGNLEGDYEVGQVANSLFRGKQPSRGSTGRLASLFGSVNPQLQPVYVPVPEEAIKKRKRDEEEESSPQIQRPLLQEPAKKMKVKKKLSDAEKKLANREDALASADLEEEIHQKQGQKRKNSQPGVTVADKELLDDVEETVVNQRKKIQINQEEERLKNERTVFVGNLPVTCNKKIPAEGTLSKKLAAIKRKIHPDQKNINAYVVFKDESAATKALERNGAQFAEGFRVRVDLATETSSRDKRSVFVGNLPYKVEESAVEKHFLACGNVVAVRIVRDQVTGVGRGFGYVLFENTDAVHLALKLNNSELMGRKLRVMRSVHKEKLKQNSNLSLKNVSKPKQGLNFASKSAQNSKGLFIGEKAVLMKKKKKGQKKSRRTKTQKKQK", "length": 408, "header": "tr|A0A3Q1LKV5-1|F6QT33_BOVIN Computationally mapped isoform of RNA-binding protein 34 OS=Bos taurus OX=9913 GN=RBM34 PE=3 SV=2 CANONICAL=F6QT33-1" }, "locus": { "chromosome": "28", "start_pos": 7922477, "end_pos": 7903263, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000070922.2", "url": "https://www.ensembl.org/id/ENSBTAT00000070922.2" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000060321.2", "url": "https://www.ensembl.org/id/ENSBTAP00000060321.2" } ] } }, { "isoform_ac": "A0A3Q1MML7-1", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1MML7/entry", "sequence": { "sequence": "MALEGKNKREKKQSAQEGQNPDDGACGNLEGDYEVGQVANSLFRGKQPSRGSTGRLASLFGSVNPQLQPVYVPVPEEAIKKRKRDEEEESSPQIQRPLLQEPAKKMKVKKKLSDAEKKLANREDALASADLEEEIHQKQGQKRKNSQPGVTVADKELLDDVEETVVNQRKKIQINQEEERLKNERTVFVGNLPVTCNKKKLKSFFKEYGQIESVRFRSLIPAEGTLSKKLAAIKNGAQFAEGFRVRVDLATETSSRDKRSVFVGNLPYKVEESAVEKHFLACGNVVAVRIVRDQVTGVGRGFGYVLFENTDAVHLALKLNNSELMGRKLRVMRSVHKEKLKQNSNLSLKNVSKPKQGLNFASKSAQNSKGLFIGEKAVLMKKKKKGQKKSRRTKTQKKQK", "length": 400, "header": "tr|A0A3Q1MML7-1|F6QT33_BOVIN Computationally mapped isoform of RNA-binding protein 34 OS=Bos taurus OX=9913 GN=RBM34 PE=3 SV=1 CANONICAL=F6QT33-1" }, "locus": { "chromosome": "28", "start_pos": 7922477, "end_pos": 7903263, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000085618.2", "url": "https://www.ensembl.org/id/ENSBTAT00000085618.2" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000073053.1", "url": "https://www.ensembl.org/id/ENSBTAP00000073053.1" } ] } }, { "isoform_ac": "A0AAA9SBR8-1", "url": "https://www.uniprot.org/uniprotkb/A0AAA9SBR8/entry", "sequence": { "sequence": "MALEGKNKREKKQSAQEGQNPDDGACGNLEGDYEVGQVANSLFRGKQPSRGSTGRLASLFGSVNPQLQPVYVPVPEEAIKKRKRDEEEESSPQIQRPLLQEPAKKMKVKKKLSDAEKKLANREDALASADLEEEIHQKQGQKRKNSQPGVTVADKELLDDVEETVVNQRKKIQINQEEERLKNERTVFVGNLPVTCNKKKLKSFFKEYGQIESVRFRSLDESAATKALERNGAQFAEGFRVRVDLATETSSRDKRSVFVGNLPYKVEESAVEKHFLACGNVVAVRIVRDQVTGVGRGFGYVLFENTDAVHLALKLNNSELMGRKLRVMRSVHKEKLKQNSNLSLKNVSKPKQGLNFASKSAQNSKGLFIGEKAVLMKKKKKGQKKSRRTKTQKKQK", "length": 396, "header": "tr|A0AAA9SBR8-1|F6QT33_BOVIN Computationally mapped isoform of RNA-binding protein 34 OS=Bos taurus OX=9913 GN=RBM34 PE=3 SV=1 CANONICAL=F6QT33-1" }, "locus": { "chromosome": "28", "start_pos": 7922477, "end_pos": 7903263, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000124002.1", "url": "https://www.ensembl.org/id/ENSBTAT00000124002.1" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000079676.1", "url": "https://www.ensembl.org/id/ENSBTAP00000079676.1" } ] } }, { "isoform_ac": "F6QT33-1", "url": "https://www.uniprot.org/uniprotkb/F6QT33/entry", "sequence": { "sequence": "MALEGKNKREKKQSAQEGQNPDDGACGNLEGDYEVGQVANSLFRGKQPSRGSTGRLASLFGSVNPQLQPVYVPVPEEAIKKRKRDEEEESSPQIQRPLLQEPAKKMKVKKKLSDAEKKLANREDALASADLEEEIHQKQGQKRKNSQPGVTVADKELLDDVEETVVNQRKKIQINQEEERLKNERTVFVGNLPVTCNKKKLKSFFKEYGQIESVRFRSLIPAEGTLSKKLAAIKRKIHPDQKNINAYVVFKDESAATKALERNGAQFAEGFRVRVDLATETSSRDKRSVFVGNLPYKVEESAVEKHFLACGNVVAVRIVRDQVTGVGRGFGYVLFENTDAVHLALKLNNSELMGRKLRVMRSVHKEKLKQNSNLSLKNVSKPKQGLNFASKSAQNSKGLFIGEKAVLMKKKKKGQKKSRRTKTQKKQK", "length": 428, "header": "tr|F6QT33-1|F6QT33_BOVIN Isoform 1 of RNA-binding protein 34 OS=Bos taurus OX=9913 GN=RBM34 PE=3 SV=1 CANONICAL=F6QT33-1" }, "locus": { "chromosome": "28", "start_pos": 7922477, "end_pos": 7903263, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000057151.3", "url": "https://www.ensembl.org/id/ENSBTAT00000057151.3" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000052119.2", "url": "https://www.ensembl.org/id/ENSBTAP00000052119.2" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [ { "id": "bta:537542", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?bta:537542", "resource": "KEGG Pathway" } ], "orthologs": [ { "uniprot_canonical_ac": "A0A8V0Y6A1-1", "protein_name": "RNA-binding protein 34", "gene_name": "RBM34", "tax_id": 9031, "organism": "Gallus gallus", "sequence": { "sequence": "MAAPRRAAEPPAGALCGDYVVGQVVGSLFSGGAAAARPLAGLFRAAAPPPVLVAVPREKKRKRTEAEVSEGQSSAVREEPPKKVKKTRKKELSKAEEKLASRESALEQADEDEEQKLLQSKAKQKKRASHAVTKSGGNSGAGRAVKQEKKKNEAEEMIKNKRTVFVGNLPVDCTAQMLKSLFKEYGQIESIRFRSVVPAEDTLSRKLAAIKRKIHPNVKYINAYVVFKEERDAVKALKKNGTEVASGFHIRVDSASKNSLHDNKRSVFLGNLAYDISDSAVREHFADCGDVVAVRIVRDRQSGMGKGFGYVLFENTDAVHLALKLNNSDLMGRKLRVKRCVEKGKAPQRSTTSRPRGPMDRAQSTLRNRRGSHDSFVGEKANPAKKSAKPKRLKSITKKKGGKNK", "length": 405 }, "evidence": [ { "id": "F6QT33", "url": "https://omabrowser.org/oma/group/F6QT33/", "database": "OMA" } ], "glygen_name": "Chicken", "common_name": "Chicken" }, { "uniprot_canonical_ac": "P42696-1", "protein_name": "RNA-binding protein 34", "gene_name": "RBM34", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MALEGMSKRKRKRSVQEGENPDDGVRGSPPEDYRLGQVASSLFRGEHHSRGGTGRLASLFSSLEPQIQPVYVPVPKQTIKKTKRNEEEESTSQIERPLSQEPAKKVKAKKKHTNAEKKLADRESALASADLEEEIHQKQGQKRKNSQPGVKVADRKILDDTEDTVVSQRKKIQINQEEERLKNERTVFVGNLPVTCNKKKLKSFFKEYGQIESVRFRSLIPAEGTLSKKLAAIKRKIHPDQKNINAYVVFKEESAATQALKRNGAQIADGFRIRVDLASETSSRDKRSVFVGNLPYKVEESAIEKHFLDCGSIMAVRIVRDKMTGIGKGFGYVLFENTDSVHLALKLNNSELMGRKLRVMRSVNKEKFKQQNSNPRLKNVSKPKQGLNFTSKTAEGHPKSLFIGEKAVLLKTKKKGQKKSGRPKKQRKQK", "length": 430 }, "evidence": [ { "id": "F6QT33", "url": "https://omabrowser.org/oma/group/F6QT33/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "Q5M9F1-1", "protein_name": "RNA-binding protein 34", "gene_name": "Rbm34", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MALRGEGRKRKKGQERRQSSEDDVGNAATDYLVGQVADSLRGGARPPGGGTGRLAALFSTPETLAPPVFVPVPQETSKKRKPDDEEETVAHIKKPALQEPARKVKVKKLSDADKRLANRESALANADLEEIRQDQGQGRRRSQSRGKVTDGEALDVALSLNEDGRQRTKVPLNPEEERLKNERTVFVGNLPVTCNKKKLKSFFKEYGQVESVRFRSVMPAEGTLSKKLAAIKRKFHPDQKSINAYVVFKEERAAAKALQRNGAQIAEGFRIRVDLASETASRDKRSVFVGNLPYRVDESALEEHFLDCGSIVAVRIVRNPLTGVGRGFGYVLFENTDAVHLALKLNNSELMGRKLRVMRSVNKEKLKQQNSNPSVKKDGSKSKQRLNFTSKEGKSHSKNAFIGEKAVLMKKKKGQKKKGQTKKPRKQK", "length": 428 }, "evidence": [ { "id": "F6QT33", "url": "https://omabrowser.org/oma/group/F6QT33/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "Q8C5L7-1", "protein_name": "RNA-binding protein 34", "gene_name": "Rbm34", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MALGGEERKRRKGSERRQSSGDGVSCAASDYLVGQVADSLRGGPRPPGGGTGRLAALFSTAEPSAPPVFVPVPQETSKKRKLDDDDDDEEESVSQTKKPVLQEPSRKVKVKKLSDADKRLANRESALASADLEEELHQDQGQGRRRRSQSRGKVADGEALDVALSLAKDGGQRTKIPVNPEEERLKNERTVFVGNLPVTCNKKKLKSFFKEYGQVESVRFRSVMPAEGTLTKKLAAIKRKFHPDQKSINAYVVFKDESAAAKALQRNGAQIAEGFRIRVDLASETASRDKRSVFVGNLPYKIEDSALEEHFLDCGSIVAVRIVRNPLTGVGRGFGYVLFENTDAVHLALKLNNSELMGRKLRVMRSVNKEKLKQQNSNPSLKKDVIKPKQRLNFTSKEGKFHSKEGKFHSKNAFIGEKAVLMKKKKKGQKKKVQMKKPRKQQ", "length": 442 }, "evidence": [ { "id": "F6QT33", "url": "https://omabrowser.org/oma/group/F6QT33/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q9VJG2-1", "protein_name": "RRM domain-containing protein", "gene_name": "cg12288", "tax_id": 7227, "organism": "Drosophila melanogaster", "sequence": { "sequence": "MKTPKAKESEKAELKPIKKEPGVVEDGKVTKKSKTKPKKKTVKVPKDEVKAAVQESPKKLSAKDLAKIEKKKAKKQAQKLKKQQNKLAPKEIKTEPEAQVKVESKATKKEKVEKEPTTAPNEKPKGKVSKKAKANANNKDEEGVKRIRNPAEEASTVFVGNLPINTKRVQLVKLFQPYGLVQSIRLRTAGGKQLFKHKQRKVAGSLNAYVVLEKPEIAQQALALNGSEFKENHLRVTPASMAEKFGQAKDKQPSDKDAKRTIFVGSLKYSATEEQLREIFSSCGEIDYIRCLQDGDKGCKGVAYVCFQKPDAVGLALELNQTLLDDRPINVERYQVKKLGAKQVRDAAAASAASKTSSKTKAKNQNSAGAKKRLDKKKGKENGSLKKEGAPTGQKKKSEYRGVKVDGIKKAKKPKKKSNDQQTALAKKIAPKQKS", "length": 435 }, "evidence": [ { "id": "F6QT33", "url": "https://omabrowser.org/oma/group/F6QT33/", "database": "OMA" } ], "glygen_name": "Fruit fly", "common_name": "Fruit fly" } ], "go_annotation": { "categories": [ { "name": "Molecular Function", "total": 1, "go_terms": [ { "name": "RNA binding", "id": "GO:0003723", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003723", "evidence": [ { "database": "UniProtKB", "id": "F6QT33", "url": "https://www.uniprot.org/uniprotkb/F6QT33" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 1, "go_terms": [ { "name": "nucleolus", "id": "GO:0005730", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005730", "evidence": [ { "database": "UniProtKB", "id": "F6QT33", "url": "https://www.uniprot.org/uniprotkb/F6QT33" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 1, "go_terms": [ { "name": "maturation of LSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)", "id": "GO:0000463", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000463", "evidence": [ { "database": "UniProtKB", "id": "F6QT33", "url": "https://www.uniprot.org/uniprotkb/F6QT33" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 348, "end_pos": 350, "annotation": "n_glycosylation_sequon" }, { "start_pos": 373, "end_pos": 375, "annotation": "n_glycosylation_sequon" }, { "start_pos": 378, "end_pos": 380, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [ { "pdb_id": "AF-F6QT33-F1", "pdb_chain": "global", "start_pos": 1, "end_pos": 428, "overlap": "1.0", "method": "AlphaFold", "type": "alphafold", "resolution": -1.0, "url": "https://data.glygen.org/ln2downloads/pdb/current/AF-F6QT33-F1.pdb", "url_external": "https://alphafold.ebi.ac.uk/entry/F6QT33" } ], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "F6QT33", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F6QT33" }, { "id": "PS50102", "database": "PROSITE", "url": "https://prosite.expasy.org/PS50102" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "RRM", "eco_id": "ECO_0000259", "start_pos": 185, "end_pos": 280, "start_aa": "Arg", "end_aa": "Glu", "glycosite_overlap": [] } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" }, { "name": "homologset.oma", "label": "OMA Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 348, "end_pos": 350 }, { "start_pos": 373, "end_pos": 375 }, { "start_pos": 378, "end_pos": 380 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ], "tool_support": { "graph_view": "yes" } }, { "uniprot_canonical_ac": "F1N458-1", "uniprot_ac": "F1N458", "uniprot_id": "F1N458_BOVIN", "mass": { "chemical_mass": 93718.0, "monoisotopic_mass": 93718.0 }, "refseq": { "ac": "XP_024840953", "name": "rho GTPase-activating protein 17 isoform X1", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_024840953" }, "gene_names": [ { "name": "ARHGAP17", "type": "recommended", "evidence": [ { "id": "F1N458", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1N458" } ] }, { "name": "ARHGAP17", "type": "synonym", "evidence": [ { "id": "XP_024840953", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_024840953" } ] } ], "protein_names": [ { "name": "Rho GTPase-activating protein 17", "type": "recommended", "evidence": [ { "id": "F1N458", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1N458/entry#names_and_taxonomy" } ] }, { "name": "Rho-type GTPase-activating protein 17", "type": "synonym", "evidence": [ { "id": "F1N458", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1N458/entry#names_and_taxonomy" } ] }, { "name": "rho GTPase-activating protein 17 isoform X1", "type": "synonym", "evidence": [ { "id": "XP_024840953", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_024840953" } ] } ], "function": [ { "annotation": "Rho GTPase-activating protein involved in the maintenance of tight junction by regulating the activity of CDC42, thereby playing a central role in apical polarity of epithelial cells. Specifically acts as a GTPase activator for the CDC42 GTPase by converting it to an inactive GDP-bound state. The complex formed with AMOT acts by regulating the uptake of polarity proteins at tight junctions, possibly by deciding whether tight junction transmembrane proteins are recycled back to the plasma membrane or sent elsewhere. Participates in the Ca(2+)-dependent regulation of exocytosis, possibly by catalyzing GTPase activity of Rho family proteins and by inducing the reorganization of the cortical actin filaments. Acts as a GTPase activator in vitro for RAC1.", "evidence": [ { "database": "UniProtKB", "id": "A0A3Q1LLI7", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1LLI7#function" }, { "database": "UniProtKB", "id": "ARBA00055904", "url": "https://www.uniprot.org/uniprotkb/ARBA00055904#function" }, { "database": "UniProtKB", "id": "A0A3Q1LN72", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1LN72#function" }, { "database": "UniProtKB", "id": "A0A3Q1M1P3", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1M1P3#function" }, { "database": "UniProtKB", "id": "F1N458", "url": "https://www.uniprot.org/uniprotkb/F1N458#function" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Bos taurus", "taxid": 9913, "evidence": [ { "database": "UniProtKB", "id": "F1N458", "url": "https://www.uniprot.org/uniprotkb/F1N458" } ], "common_name": "Bovine", "glygen_name": "Bovine", "reference_species": "Bos taurus [9913]" } ], "gene": [ { "name": "ARHGAP17", "url": "https://www.uniprot.org/uniprotkb/F1N458", "locus": { "chromosome": "25", "start_pos": 22576611, "end_pos": 22676744, "strand": "+", "evidence": [ { "database": "Ensembl Gene", "id": "ENSBTAG00000020043", "url": "https://www.ensembl.org/id/ENSBTAG00000020043" } ] } } ], "crossref": [ { "id": "F1N458", "url": "https://alphafold.ebi.ac.uk/entry/F1N458", "database": "AlphaFoldDB", "categories": [] }, { "id": "ENSBTAG00000020043", "url": "https://bgee.org/?page=gene&gene_id=ENSBTAG00000020043", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "cd04386", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd04386", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "cd07618", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd07618", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "504245", "url": "https://www.ncbi.nlm.nih.gov/gene/504245", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR000198", "url": "https://www.ebi.ac.uk/interpro/entry/IPR000198", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR004148", "url": "https://www.ebi.ac.uk/interpro/entry/IPR004148", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR008936", "url": "https://www.ebi.ac.uk/interpro/entry/IPR008936", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR027267", "url": "https://www.ebi.ac.uk/interpro/entry/IPR027267", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR047165", "url": "https://www.ebi.ac.uk/interpro/entry/IPR047165", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "bta:504245", "url": "https://www.genome.jp/dbget-bin/www_bget?bta:504245", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "REHRRSW", "url": "https://omabrowser.org/oma/group/REHRRSW/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "A0A3Q1LLI7", "url": "https://www.orthodb.org/?gene=A0A3Q1LLI7", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A3Q1LN72", "url": "https://www.orthodb.org/?gene=A0A3Q1LN72", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A3Q1M1P3", "url": "https://www.orthodb.org/?gene=A0A3Q1M1P3", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "F1N458", "url": "https://www.orthodb.org/?gene=F1N458", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR14130", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR14130", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR14130:SF3", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR14130:SF3", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00620", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00620", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF03114", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF03114", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "R-BTA-9013148", "url": "https://www.reactome.org/PathwayBrowser/#R-BTA-9013148", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "R-BTA-9013404", "url": "https://www.reactome.org/PathwayBrowser/#R-BTA-9013404", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "R-BTA-9013406", "url": "https://www.reactome.org/PathwayBrowser/#R-BTA-9013406", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "R-BTA-9013423", "url": "https://www.reactome.org/PathwayBrowser/#R-BTA-9013423", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "XP_024840953", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_024840953", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A3Q1LLI7", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1LLI7", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A3Q1LLI7-1", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1LLI7-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A3Q1LN72", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1LN72", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A3Q1LN72-1", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1LN72-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A3Q1M1P3", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1M1P3", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A3Q1M1P3-1", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1M1P3-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "F1N458", "url": "https://www.uniprot.org/uniprotkb/F1N458", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "F1N458-1", "url": "https://www.uniprot.org/uniprotkb/F1N458-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MKKQFNRMKQLANQTVGRAEKTEVLSEDLLQIERRLDTVRSMCHHSHKRLMACFQGQHGTDAERRHKKLPLTALAQNMLEASTQLEDSLLGKMLETCGDAENQLALELSQHEVFVEKEIVDPLYGIAEVEIPNIQKQRKQLAKLVLDWDSVRARWNQAHKSSGTNFQGLPSKIDTLKEEMDEAGNKVEQCKDQLAADMYNFMAKEGEYGKFFITLLEAQADYHRKALAVLEKALPELRAHQDKWAEKPAFGTPLEEHLKRSGREIALPIEACVMLLLETGMKEEGLFRIGAGASKLKKLKAALDCSTSHLDEFYSDPHAVAGALKSYLRELPEPLMTFNLYEEWTQVASVQDQDKKLQDLWRTCQKLPPQNFVNFRYLIKFLAKLAQTSDINKMTPSNIAIVLGPNLLWAKNEGTLAEMAAATSVHVVAVIEPIIQHANWFFPEEVEFNVSEAFVPLTTPNSNHSSHTGNDPVDSGTLERKRPASMAVMEGDLVKKESFGVKLMDFQAHRRGGTLNRKHVSPAFQPPLPPTDGSTLAPAGPEPPPQSSRAESSTGGGTGPSSAGILEQGPSPGDSSPPKPKDSVAAPAPGRNSSQAAPGPSQAQAAAGSHQLSVGPAHNSAGPSPHTVRRAVKKPAPAPPKPGNPPPGHPGGQSSPGTSQHPPSLSPKPSTRSPSPPTQPPGQAPGQPCATSQLSAPRRYSSSLPPIQAPNHPPPQPPTQAASPSALTKPGSQGPPAPGEPGLEQSSHTPPQTPTPPSTPPLGKQNPGQAVSNPETAQPHAGTLPRPRPVPKPRNRPNVPPPPHPPGAHAAGDGNLSIAAPTASKIVTDANSRVSEPLRSIFPEMHSDSASKDLPGRILLDMDNDTESTAL", "length": 871, "header": "tr|F1N458-1|F1N458_BOVIN Isoform 1 of Rho GTPase-activating protein 17 OS=Bos taurus OX=9913 GN=ARHGAP17 PE=4 SV=3 CANONICAL=F1N458-1" }, "isoforms": [ { "isoform_ac": "A0A3Q1LLI7-1", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1LLI7/entry", "sequence": { "sequence": "MKKQFNRMKQLANQTVGRAEKTEVLSEDLLQIERRLDTVRSMCHHSHKRLMACFQGQHGTDAERRHKKLPLTALAQNMLEASTQLEDSLLGKMLETCGDAENQLALELSQHEVFVEKEIVDPLYGIAEVEIPNIQKQRKQLAKLVLDWDSVRARWNQAHKSSGTNFQGLPSKIDTLKEEMDEAGNKVEQCKDQLAADMYNFMAKEGEYGKFFITLLEAQADYHRKALAVLEKALPELRAHQDKWAEKPAFGTPLEEHLKRSGREIALPIEACVMLLLETGMKEEGLFRIGAGASKLKKLKAALDCSTSHLDEFYSDPHAVAGALKSYLRELPEPLMTFNLYEEWTQVASVQDQDKKLQDLWRTCQKLPPQNFVNFRYLIKFLAKLAQTSDINKMTPSNIAIVLGPNLLWAKNEGTLAEMAAATSVHVVAVIEPIIQHANWFFPEEVEFNVSEAFVPLTTPNSNHSSHTGNDPVDSGTLERKRPASMAVMEGDLVKKESFGVKLMDFQAHRRGGTLNRKHVSPAFQPPLPPTDGSTLAPAGPEPPPQSSRAESSTGGGTGPSSAGILEQGPSPGDSSPPKPKDSVAAPAPGRNSSQAAPGPSQAQAAAGSHQLSVGPAHNSAGPSPHTVRRAVKKPAPAPPKPGNPPPGHPGGQSSPGTSQHPPSLSPKPSTRSPSPPTQPPGQAPGQPCATSQLSAPRRYSSSLPPIQAPNHPPPQPPTQAASPSALTKPGSQGPPAPGEPGLEQSSHTPPQTPTPPSTPPLGKQNPGQAVSNPETAQPHAGTLPRPRPVPKPRNRPNVPPPPHPPGAHAAGDGNLSIAAPTASKIVTDV", "length": 830, "header": "tr|A0A3Q1LLI7-1|F1N458_BOVIN Computationally mapped isoform of Rho GTPase-activating protein 17 OS=Bos taurus OX=9913 GN=ARHGAP17 PE=4 SV=2 CANONICAL=F1N458-1" }, "locus": { "chromosome": "25", "start_pos": 22676455, "end_pos": 22582895, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000082761.2", "url": "https://www.ensembl.org/id/ENSBTAT00000082761.2" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000060641.2", "url": "https://www.ensembl.org/id/ENSBTAP00000060641.2" } ] } }, { "isoform_ac": "A0A3Q1LN72-1", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1LN72/entry", "sequence": { "sequence": "MKKQFNRMKQLANQTVGRAEKTEVLSEDLLQIERRLDTVRSMCHHSHKRLMACFQGQHGTDAERRHKKLPLTALAQNMLEASTQLEDSLLGKMLETCGDAENQLALELSQHEVFVEKEIVDPLYGIAEVEIPNIQKQRKQLAKLVLDWDSVRARWNQAHKSSGTNFQGLPSKIDTLKEEMDEAGNKVEQCKDQLAADMYNFMAKEGEYGKFFITLLEAQADYHRKALAVLEKALPELRAHQDKWAEKPAFGTPLEEHLKRSGREIALPIEACVMLLLETGMKEEGLFRIGAGASKLKKLKAALDCSTSHLDEFYSDPHAVAGALKSYLRELPEPLMTFNLYEEWTQVASVQDQDKKLQDLWRTCQKLPPQNFVNFRYLIKFLAKLAQTSDINKMTPSNIAIVLGPNLLWAKNEGTLAEMAAATSVHVVAVIEPIIQHANWFFPEEVEFNVSEAFVPLTTPNSNHSSHTGNDPVDSGTLERKRPASMAVMEGDLVKKESPPKPKDSVAAPAPGRNSSQAAPGPSQAQAAAGSHQLSVGPAHNSAGPSPHTVRRAVKKPAPAPPKPGNPPPGHPGGQSSPGTSQHPPSLSPKPSTRSPSPPTQPPGQAPGQPCATSQLSAPRRYSSSLPPIQAPNHPPPQPPTQAASPSALTKPGSQGPPAPGEPGLEQSSHTPPQTPTPPSTPPLGKQNPGQAVSNPETAQPHAGTLPRPRPVPKPRNRPNVPPPPHPPGAHAAGDGNLSIAAPTASKIVTDANSRVSEPLRSIFPEMHSDSASKDLPGRILLDMDNDTESTAL", "length": 793, "header": "tr|A0A3Q1LN72-1|F1N458_BOVIN Computationally mapped isoform of Rho GTPase-activating protein 17 OS=Bos taurus OX=9913 GN=ARHGAP17 PE=4 SV=1 CANONICAL=F1N458-1" }, "locus": { "chromosome": "25", "start_pos": 22676455, "end_pos": 22577214, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000068574.3", "url": "https://www.ensembl.org/id/ENSBTAT00000068574.3" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000058396.1", "url": "https://www.ensembl.org/id/ENSBTAP00000058396.1" } ] } }, { "isoform_ac": "A0A3Q1M1P3-1", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1M1P3/entry", "sequence": { "sequence": "MKKQFNRMKQLANQTVGRAEKTEVLSEDLLQIERRLDTVRSMCHHSHKRLMACFQGQHGTDAERRHKKLPLTALAQNMLEASTQLEDSLLGKMLETCGDAENQLALELSQHEVFVEKEIVDPLYGIAEVEIPNIQKQRKQLAKLVLDWDSVRARWNQAHKSSGTNFQGLPSKIDTLKEEMDEAGNKVEQCKDQLAADMYNFMAKEGEYGKFFITLLEAQADYHRKALAVLEKALPELRAHQDKWAEKPAFGTPLEEHLKRSGREIALPIEACVMLLLETGMKEEGLFRIGAGASKLKKLKAALDCSTSHLDEFYSDPHAVAGALKSYLRELPEPLMTFNLYEEWTQVASVQDQDKKLQDLWRTCQKLPPQNFVNFRYLIKFLAKLAQTSDINKMTPSNIAIVLGPNLLWAKNEGTLAEMAAATSVHVVAVIEPIIQHANWFFPEEVEFNVSEAFVPLTTPNSNHSSHTGNDPVDSGTLERKRPASMAVMEGDLVKKESFGVKLMDFQAHRRGGTLNRKHVSPAFQPPLPPTDGSTLAPAGPEPPPQSSRAESSTGGGTGPSSAGILEQGPSPGDSSPPKPKDSVAAPAPGRNSSQAAPGPSQAQAAAGSHQLSVGPAHNSAGPSPHTVRRAVKKPAPAPPKPGNPPPGHPGGQSSPGTSQHPPSLSPKPSTRSPSPPTQPPGQAPGQPCATSQLSAPRRYSSSLPPIQAPNHPPPQPPTQAASPSALTKPGSQGPPAPGEPGLEQSSHTPPQTPTPPSTPPLGKQNPGQAVSNPETAQPHAGTLPRPRPVPKPRNRPNVPPPPHPPGAHAAGDGNLSIAAPTASKIVTDALPSALTGGEGFQE", "length": 843, "header": "tr|A0A3Q1M1P3-1|F1N458_BOVIN Computationally mapped isoform of Rho GTPase-activating protein 17 OS=Bos taurus OX=9913 GN=ARHGAP17 PE=4 SV=2 CANONICAL=F1N458-1" }, "locus": { "chromosome": "25", "start_pos": 22676455, "end_pos": 22584639, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000086368.2", "url": "https://www.ensembl.org/id/ENSBTAT00000086368.2" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000063655.2", "url": "https://www.ensembl.org/id/ENSBTAP00000063655.2" } ] } }, { "isoform_ac": "F1N458-1", "url": "https://www.uniprot.org/uniprotkb/F1N458/entry", "sequence": { "sequence": "MKKQFNRMKQLANQTVGRAEKTEVLSEDLLQIERRLDTVRSMCHHSHKRLMACFQGQHGTDAERRHKKLPLTALAQNMLEASTQLEDSLLGKMLETCGDAENQLALELSQHEVFVEKEIVDPLYGIAEVEIPNIQKQRKQLAKLVLDWDSVRARWNQAHKSSGTNFQGLPSKIDTLKEEMDEAGNKVEQCKDQLAADMYNFMAKEGEYGKFFITLLEAQADYHRKALAVLEKALPELRAHQDKWAEKPAFGTPLEEHLKRSGREIALPIEACVMLLLETGMKEEGLFRIGAGASKLKKLKAALDCSTSHLDEFYSDPHAVAGALKSYLRELPEPLMTFNLYEEWTQVASVQDQDKKLQDLWRTCQKLPPQNFVNFRYLIKFLAKLAQTSDINKMTPSNIAIVLGPNLLWAKNEGTLAEMAAATSVHVVAVIEPIIQHANWFFPEEVEFNVSEAFVPLTTPNSNHSSHTGNDPVDSGTLERKRPASMAVMEGDLVKKESFGVKLMDFQAHRRGGTLNRKHVSPAFQPPLPPTDGSTLAPAGPEPPPQSSRAESSTGGGTGPSSAGILEQGPSPGDSSPPKPKDSVAAPAPGRNSSQAAPGPSQAQAAAGSHQLSVGPAHNSAGPSPHTVRRAVKKPAPAPPKPGNPPPGHPGGQSSPGTSQHPPSLSPKPSTRSPSPPTQPPGQAPGQPCATSQLSAPRRYSSSLPPIQAPNHPPPQPPTQAASPSALTKPGSQGPPAPGEPGLEQSSHTPPQTPTPPSTPPLGKQNPGQAVSNPETAQPHAGTLPRPRPVPKPRNRPNVPPPPHPPGAHAAGDGNLSIAAPTASKIVTDANSRVSEPLRSIFPEMHSDSASKDLPGRILLDMDNDTESTAL", "length": 871, "header": "tr|F1N458-1|F1N458_BOVIN Isoform 1 of Rho GTPase-activating protein 17 OS=Bos taurus OX=9913 GN=ARHGAP17 PE=4 SV=3 CANONICAL=F1N458-1" }, "locus": { "chromosome": "25", "start_pos": 22676455, "end_pos": 22577214, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000026703.7", "url": "https://www.ensembl.org/id/ENSBTAT00000026703.7" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000026703.6", "url": "https://www.ensembl.org/id/ENSBTAP00000026703.6" } ] } } ], "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "other", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 531, "start_aa": "Thr", "end_pos": 531, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr531", "evidence": [ { "id": "", "database": "GlyGen", "url": "https://data.glygen.org/" } ], "filter_code": "000000000000000010000.00000000001000.0.01000" }, { "glytoucan_ac": "", "type": "O-linked", "subtype": "other", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 755, "start_aa": "Thr", "end_pos": 755, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr755", "evidence": [ { "id": "", "database": "GlyGen", "url": "https://data.glygen.org/" } ], "filter_code": "000000000000000010000.00000000001000.0.01000" } ], "phosphorylation": [], "glycation": [], "keywords": [ "glycoprotein", "glycoprotein_predicted" ], "publication": [], "pathway": [ { "id": "bta:504245", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?bta:504245", "resource": "KEGG Pathway" }, { "id": "R-BTA-9013148", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-BTA-9013148", "resource": "Reactome", "description": "CDC42 GTPase cycle" }, { "id": "R-BTA-9013404", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-BTA-9013404", "resource": "Reactome", "description": "RAC2 GTPase cycle" }, { "id": "R-BTA-9013406", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-BTA-9013406", "resource": "Reactome", "description": "RHOQ GTPase cycle" }, { "id": "R-BTA-9013423", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-BTA-9013423", "resource": "Reactome", "description": "RAC3 GTPase cycle" } ], "orthologs": [ { "uniprot_canonical_ac": "A0A286ZZA8-1", "protein_name": "Rho GTPase-activating protein 17", "gene_name": "ARHGAP17", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MKKQFNRMKQLANQTVGRAEKTEVLSEDLLQIERRLDTVRSMCHHSHKRLMACFQGQHGTDAERRHKKLPLTALAQNMQEASTQLEDSLLGKMLETCGDAENQLALELSQHEVFVEKEIVDPLYGIAEVEIPNIQKQRKQLAKLVLDWDSVRARWNQAHKSSATNFQGLPSKIDTLKEEMDEAGNKVEQCKDQLAADMYNFMAKEGEYGKFFVTLLEAQADYHRKALAVLEKALPELRAHQDKWAEKPAFGTPLEEHLKRSGREIALPIEACVMLLLETGMKEEGLFRIGAGASKLKKLKAALDCSTSHLDEFYSDPHAVAGALKSYLRELPEPLMTFNLYEEWTQVASVQDQDKKLQDLWRTCQKLPPHNFVNFRYLIKFLAKLAQTSDINKMTPSNIAIVLGPNLLWAKNEGTLAEMAAATSVHVVAVIEPIIQHANWFFPEEVEFNVSEAFVPLATPTSNHSSHTGIDSVDSGTLERKRPASMAVMEGDLVKKESFGVKLMDFQAHRRGGTLNRKHISPAFQPPLPPTDGSTLAPAGPEPPPQSSRAESSTGGGTVPSTAGMLEQGPSPGDSSPPKPKDSATAPAPGRNSSQAATGQSQAQAAAGSHQLSVGPAHNSAGPSPHTLRRAVKKPAPAPPKPGNPPPGHPGAQSSPGTSQHPPSLSPKPSTRSPSPPTQPPGQAPGQPGATSQLSAPRRYSSSLPPIQAPNHPPPQPPTQATPPPALAKPGSQGPAAPVALPGEHGLEQLSHTPPQTPTPPSTPPLGKQNPGGPPAAPTQAGSNTESAQPHAGTLPRPRPVPKPRNRPSMPPPPHPPGAHPTAADGSLSIAAPTASKIVTDANPRASEPLRSLFPEMHSDSASKDLPGRILLDMDNDTESTAL", "length": 883 }, "evidence": [ { "id": "F1N458", "url": "https://omabrowser.org/oma/group/F1N458/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "A0A8V0Z535-1", "protein_name": "Rho GTPase-activating protein 17", "gene_name": "ARHGAP17", "tax_id": 9031, "organism": "Gallus gallus", "sequence": { "sequence": "MKKQFNRMKQLANQTVGRAEKTEVLSEDLLQIERRLDTVRSVFHIAQKRLIACFQGQYGTDPDKRHKKLPLTALAQNMQEGSAQLSDETLLGKMLDTCGDAENKLALELSQHEVQIEKDILEPLNTLTEVEIPNIQKQRKQLAKLVLDWDSARGRYNQAHKTSGTNFQMHPSKIDSLKEEMDEAGNKVEQCKDQLAADMYNFVSKEGEYAKFFVMLLEAQADYHRKALAVIEKVLPEIQAHQDKWTEKPAFGTPLEEHLKRSGREIAIPIEACVMMLLETGMREEGLFRIAAGASKLKKLKAALDCSTSQLDEFYSDPHAVAGALKSYLRELPEPLMTYALYEEWTQAANIQDQDKKLQELWKICNKLPKHYHANFRYLIKFLAKLAQNSDVNKMTPSNVAIVLGPNLLWAKTEGSLAEMAAATSVHVVAIIEPIIQHADWFFPGDQDFNVSGAFVAVPAVNSNHLSHTGNEYDSGTLERKRPVSMAVMEGDLLKKESFGVKVMDFQANPRRCGTINRKHTSPAFQPPLPPTEAGVLAHSGVEQHSQAAVAETSPVGAGFALSAGTAEQLQSQGNEDVSTSKPKDSTSSATPPPMRNGGHVSTAPNQSASSTNQLSVNQPQNAAGPSPHSMRRAVKKPAPAPPKPANPPPGQPGSQSSAPAAQPPSISPKPLARSSSPPAQHANQGAAMTSSSQVSAPRRYSSSLSPIQAPSHPPPQPPTQATPPLQPKANNQASPSAPSSEHGPEQPCYTPPQTPTPPDTPPLGKHSTTSPPSQPQSSTQDTSQSHSPPHSGTLPRPRPVPKPRNRPSVPPPPHPPSQLAGDGIIANPTQTASKIVTDSNSSIPEPLQNASAELPTEAAGKELHNHLALDIDNDTESTAL", "length": 881 }, "evidence": [ { "id": "F1N458", "url": "https://omabrowser.org/oma/group/F1N458/", "database": "OMA" } ], "glygen_name": "Chicken", "common_name": "Chicken" }, { "uniprot_canonical_ac": "Q3UIA2-1", "protein_name": "Rho GTPase-activating protein 17", "gene_name": "Arhgap17", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MKKQFNRMKQLANQTVGRAEKTEVLSEDLLQIERRLDTVRSMCHHSHKRLIACFQGQHGTDAERRHKKLPLTALAQNMQEASAQLEESLLGKMLETCGDAENQLALELSQHEVFVEKEIMDPLYGIAEVEIPNIQKQRKQLARLVLDWDSVRARWNQAHKSSGTNFQGLPSKIDTLKEEMDEAGNKVEQCKDQLAADMYNFMAKEGEYGKFFVTLLEAQADYHRKALAVLEKALPEMRAHQDKWAEKPAFGTPLEEHLKRSGREIALPIEACVMLLLETGMKEEGLFRIGAGASKLKKLKAALDCSTSHLDEFYSDPHAVAGALKSYLRELPEPLMTFSLYEEWTQVASVQDQDKKLQYLWTTCQKLPPQNFVNFRYLIKFLAKLAQTSDVNKMTPSNIAIVLGPNLLWAKQEGTLAEIAAATSVHVVAVIEPIIQHADWFFPGEVEFNVSEAFVPLATPNSNHSSHTGNDSDSGTLERKRPASMAVMEGDLVKKESFGVKLMDFQAHRRGGTLNRKHIAPAFQPPLPPTDGNALAPAGPEPPSQSSRADSSSGGGPVFSSTGILEQGLSPGDSSPPKPKDSVSAAVPAAGRNSNQMTTVPNQAQTGGNSHQLSVSTPHSAAGPSPHTLRRAVKKPAPAPPKPGNLPPGHPGGQSSPGTGTSPKPSARSPSPPQQQQQQQQQQQQQQQQQTPGMRRCSSSLPPIQAPSHPPPQPPTQPRLGEQGPEPGPTPPQTPTPPSTPPLAKQNPSQSETTQLHGTLPRPRPVPKPRNRPSVPPPPHPPGTHTVDGGLTSSVPTASRIVTDTNSRVSESLRSIFPEIHSDLASKEVPGHILLDIDNDTESTAL", "length": 846 }, "evidence": [ { "id": "F1N458", "url": "https://omabrowser.org/oma/group/F1N458/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q54MV3-1", "protein_name": "Rho GTPase-activating protein gacJ", "gene_name": "gacJ", "tax_id": 44689, "organism": "Dictyostelium discoideum", "sequence": { "sequence": "MEEQQPPSIKKKIVDFLTNFLKKRPSHEDLRRDNILVAPNNVSPAIQPSRYELEGHLNPSSHNRDDSSNNNNNNNNNNNTVEYSRGHSKSHSRSDSKHHNRENSKSDRDNSRSDNIRFGRKDTFKNAWDYLRNIDFTFSKTKYGNTVVHRLKHPQFGLSPEELQSLYPDQPHGIPIVLTKCFEYLSKHLETEGLFRVPGSNREVSLLKFKIEDGDLDFSEVLIPYNICGLISTFFKELPEPLIPFDYYNDAILITKLGSKDKYIIGLRDLVLSLPPANLCMLRKLLEFLLTVEKKNEFNKMTISNISIIFGVTLLKDPDTVDPMKSLNNIQAQSTIIKYMLEYFNDIFKEASVVKAYRKSIVPKEPMDTTSISYLDPAESNGGSPRTSNTPYQQQHQLSSQSMANIKPRPPSRSKMMRETIVLSPRVSGGNNQVYANATMTRPMSRLFFDPEIIPSPPPTTTTTTTTTTNTTTTTTTTNTTPNNTTTVNIQQKPVPPKPNLIPRKLPPNPNYSTYPAPLPPRQPNTIPLAPIPPPKPNSTYKKQITQPPPPRKPTSPSPPIATLKPTSKSDFIPSTNNNLNNNNTTTTTSSLISIPKAKPPPPKRNNVVSPAIEEPINPNLNINSTTTTPTPPLASFKNNGTISSGSKSNPNLQNLLNTNQPLVSSNGPPNKPPPQPFELLKSKPITTTPTIKKGVTFSETPKISNSPPSPSSSSPSPPHNQPIIVNKPIPSKSAPPPVRTTSSPSIVTKKFVPTIPTQTTTASSSSTPTTPKNQHLSKDDSSIPPINTSQTNNNISNSSIPSPKSKSALSLSTPKDSITGKPIKPPSNSDLSISTTPLPPTSSSPTSSSPLQSPKISSPSVLTVSQKIALNEKIAANQAKKNPLSNSGGLKQISPDLIKSNNINK", "length": 906 }, "evidence": [ { "id": "F1N458", "url": "https://omabrowser.org/oma/group/F1N458/", "database": "OMA" } ], "glygen_name": "Cellular slime mold", "common_name": "Social amoeba" }, { "uniprot_canonical_ac": "Q68EM7-1", "protein_name": "Rho GTPase-activating protein 17", "gene_name": "ARHGAP17", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MKKQFNRMKQLANQTVGRAEKTEVLSEDLLQIERRLDTVRSICHHSHKRLVACFQGQHGTDAERRHKKLPLTALAQNMQEASTQLEDSLLGKMLETCGDAENQLALELSQHEVFVEKEIVDPLYGIAEVEIPNIQKQRKQLARLVLDWDSVRARWNQAHKSSGTNFQGLPSKIDTLKEEMDEAGNKVEQCKDQLAADMYNFMAKEGEYGKFFVTLLEAQADYHRKALAVLEKTLPEMRAHQDKWAEKPAFGTPLEEHLKRSGREIALPIEACVMLLLETGMKEEGLFRIGAGASKLKKLKAALDCSTSHLDEFYSDPHAVAGALKSYLRELPEPLMTFNLYEEWTQVASVQDQDKKLQDLWRTCQKLPPQNFVNFRYLIKFLAKLAQTSDVNKMTPSNIAIVLGPNLLWARNEGTLAEMAAATSVHVVAVIEPIIQHADWFFPEEVEFNVSEAFVPLTTPSSNHSFHTGNDSDSGTLERKRPASMAVMEGDLVKKESFGVKLMDFQAHRRGGTLNRKHISPAFQPPLPPTDGSTVVPAGPEPPPQSSRAESSSGGGTVPSSAGILEQGPSPGDGSPPKPKDPVSAAVPAPGRNNSQIASGQNQPQAAAGSHQLSMGQPHNAAGPSPHTLRRAVKKPAPAPPKPGNPPPGHPGGQSSSGTSQHPPSLSPKPPTRSPSPPTQHTGQPPGQPSAPSQLSAPRRYSSSLSPIQAPNHPPPQPPTQATPLMHTKPNSQGPPNPMALPSEHGLEQPSHTPPQTPTPPSTPPLGKQNPSLPAPQTLAGGNPETAQPHAGTLPRPRPVPKPRNRPSVPPPPQPPGVHSAGDSSLTNTAPTASKIVTDSNSRVSEPHRSIFPEMHSDSASKDVPGRILLDIDNDTESTAL", "length": 881 }, "evidence": [ { "id": "F1N458", "url": "https://omabrowser.org/oma/group/F1N458/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "Q99N37-1", "protein_name": "Rho GTPase-activating protein 17", "gene_name": "Arhgap17", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MKKQFNRMKQLANQTVGRAEKTEVLSEDLLQIERRLDTVRSMCHHSHKRLIACFQGQHGTDAERRHKKLPLTALAQNMQEASAQLEESLLGKMLETCGDAENQLAFELSQHEVFVEKEIMDPLYGIAEVEIPNIQKQRKQLARLVLDWDSVRARWNQAHKSSGTNFQGLPSKIDTLKEEMDEAGNKVEQCKDQLAADMYNFMAKEGEYGKFFVTLLEAQADYHRKALAVLEKALPEMRAHQDKWAEKPAFGTPLEEHLKRSGREIALPIEACVMLLLETGMKEEGLFRIGAGASKLKKLKAALDCSTSHLDEFYSDPHAVAGALKSYLRELPEPLMTFSLYEEWTQVASVQDQDKKLQYLWTTCQKLPPQNFVNFRYLIKFLAKLAQTSDVNKMTPSNIAIVLGPNLLWAKQEGTLAEIAAATSVHVVAVIEPIIQHADWFFPGEVEFNVSEAFVPLATPNSNHSSHTGNDSDSGTLERKRPASMAVMEGDLVKKESFGVKLMDFQAHRRGGTLNRKHISPAFQPPLPPTDGNALAPAGPELPSQSSRADSNSVGGPVPSSSGILEQGLSPGDSSPPKPKDSVSAAAPVAGRNSNQITTVPNQAQTGGNSHQLSVGTAHSAAGPSPHTLRRAVKKPAPAPPKPGNPPPGHPGGQSSPGTGTSPKPSTRSPSPPQQQQQQQQQQQQQQQQQQQQQQQQQQQQQTPGMRRCSSSLPPIQAPNHPPPQPPTQPRLGEQGPEPGPTPPQTPTPPSTPPPAKQNSSQSETTQLHGTLPRPRPVPKPRNRPSVPPPPNPPGTHMGDGGLTPSVPTASRIVTDTNSRVSESLRNIFPEIHSDLASKEVPGHILLDIDNDTESTAL", "length": 858 }, "evidence": [ { "id": "F1N458", "url": "https://omabrowser.org/oma/group/F1N458/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" } ], "go_annotation": { "categories": [ { "name": "Molecular Function", "total": 2, "go_terms": [ { "name": "GTPase activator activity", "id": "GO:0005096", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005096", "evidence": [ { "database": "UniProtKB", "id": "F1N458", "url": "https://www.uniprot.org/uniprotkb/F1N458" } ], "pmid": "" }, { "name": "SH3 domain binding", "id": "GO:0017124", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0017124", "evidence": [ { "database": "UniProtKB", "id": "F1N458", "url": "https://www.uniprot.org/uniprotkb/F1N458" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 5, "go_terms": [ { "name": "cytosol", "id": "GO:0005829", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005829", "evidence": [ { "database": "UniProtKB", "id": "F1N458", "url": "https://www.uniprot.org/uniprotkb/F1N458" } ], "pmid": "" }, { "name": "plasma membrane", "id": "GO:0005886", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005886", 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{ "database": "UniProtKB", "id": "F1N458", "url": "https://www.uniprot.org/uniprotkb/F1N458" } ], "pmid": "" }, { "name": "regulation of actin cytoskeleton organization", "id": "GO:0032956", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0032956", "evidence": [ { "database": "UniProtKB", "id": "F1N458", "url": "https://www.uniprot.org/uniprotkb/F1N458" } ], "pmid": "" }, { "name": "negative regulation of small GTPase mediated signal transduction", "id": "GO:0051058", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0051058", "evidence": [ { "database": "UniProtKB", "id": "F1N458", "url": "https://www.uniprot.org/uniprotkb/F1N458" } ], "pmid": "" }, { "name": "regulation of Rac protein signal transduction", "id": "GO:0035020", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0035020", "evidence": [ { "database": "UniProtKB", "id": "F1N458", "url": "https://www.uniprot.org/uniprotkb/F1N458" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 13, "end_pos": 15, 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"categories": [ "Gene Expression" ] }, { "id": "616564", "url": "https://www.ncbi.nlm.nih.gov/gene/616564", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR006594", "url": "https://www.ebi.ac.uk/interpro/entry/IPR006594", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR008116", "url": "https://www.ebi.ac.uk/interpro/entry/IPR008116", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "A0A3Q1LNR0", "url": "https://www.orthodb.org/?gene=A0A3Q1LNR0", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A3Q1LYY1", "url": "https://www.orthodb.org/?gene=A0A3Q1LYY1", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A3Q1NGE0", "url": "https://www.orthodb.org/?gene=A0A3Q1NGE0", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR12610", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR12610", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR12610:SF23", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR12610:SF23", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF04503", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF04503", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "XP_005209768", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_005209768", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A3Q1LNR0", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1LNR0", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A3Q1LNR0-1", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1LNR0-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A3Q1LYY1", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1LYY1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A3Q1LYY1-1", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1LYY1-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A3Q1NGE0", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1NGE0", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A3Q1NGE0-1", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1NGE0-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0AAA9RYF7", "url": "https://www.uniprot.org/uniprotkb/A0AAA9RYF7", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0AAA9RYF7-1", "url": "https://www.uniprot.org/uniprotkb/A0AAA9RYF7-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0AAA9TLT8", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TLT8", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0AAA9TLT8-1", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TLT8-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0AAA9TP98", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TP98", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0AAA9TP98-1", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TP98-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "F6R8M4", "url": "https://www.uniprot.org/uniprotkb/F6R8M4", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "F6R8M4-1", "url": "https://www.uniprot.org/uniprotkb/F6R8M4-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MYGKGKSNSSAVPSDSQAREKLALYVYEYLLHVGAQKSAQTFLSEIRWEKNITLGEPPGFLHSWWCVFWDLYCAAPERRETCEHSSEAKAFHDYSAAAAPSPVLGNIPPGDGMPVGPVPPGFFQPFMSPRYPGGPRPPLRIPNQALGGVPGSQPLLPSGMDPTRQQGHPNMGGPMQRMTPPRGMVPLGPQSDPWLSLQNYGGAMRPPLNALGGPGMPGMNMGPGGGRPWPNPTNANSIPYSSASPGNYVGPPGGGGPPGTPIMPSPADSTNSGDNMYTLMNAVPPGPNRPNFPMGPGSDGPMGGLGGMESHHMNGSLGSGDMDSISKNSPNNMSLSNQPGTPRDDGEMGGNFLNPFQSESYSPSMTMSV", "length": 369, "header": "tr|F6R8M4-1|F6R8M4_BOVIN Isoform 1 of Single stranded DNA binding protein 2 OS=Bos taurus OX=9913 GN=SSBP2 PE=4 SV=1 CANONICAL=F6R8M4-1" }, "isoforms": [ { "isoform_ac": "A0A3Q1LNR0-1", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1LNR0/entry", "sequence": { "sequence": "MYGKGKSNSSAVPSDSQAREKLALYVYEYLLHVGAQKSAQTFLSEIRWEKNITLGEPPGFLHSWWCVFWDLYCAAPERRETCEHSSEAKAFHDYSAAAAPSPVLGNIPPGDGMPVGPVPPGFFQALGGVPGSQPLLPSGMDPTRQQGHPNMGGPMQRMTPPRGMVPLGPQNYGGAMRPPLNALGGPGMPGMNMGPGGGRPWPNPTNANSIPYSSASPGNYVGPPGGGGPPGTPIMPSPADSTNSGDNMYTLMNAVPPGPNRPNFPMGPGSDGPMGGLGGMESHHMNGSLGSGDMDSISKNSPNNMSLSNQPGTPRDDGEMGGNFLNPFQSESYSPSMTMSV", "length": 341, "header": "tr|A0A3Q1LNR0-1|F6R8M4_BOVIN Computationally mapped isoform of Single stranded DNA binding protein 2 OS=Bos taurus OX=9913 GN=SSBP2 PE=4 SV=2 CANONICAL=F6R8M4-1" }, "locus": { "chromosome": "7", "start_pos": 81711461, "end_pos": 81402176, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000085551.2", "url": "https://www.ensembl.org/id/ENSBTAT00000085551.2" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000058638.2", "url": "https://www.ensembl.org/id/ENSBTAP00000058638.2" } ] } }, { "isoform_ac": "A0A3Q1LYY1-1", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1LYY1/entry", "sequence": { "sequence": "MYGKGKSNSSAVPSDSQAREKLALYVYEYLLHVGAQKSAQTFLSEIRWEKNITLGEPPGFLHSWWCVFWDLYCAAPERRETCEHSSEAKAFHDYSAAAAPSPVLGNIPPGDGMPVGPVPPGFFQPFMSPRYPGGPRPPLRIPNQALGGVPGSQPLLPSGMDPTRQQGHPNMGGPMQRMTPPRGMVPLGPQNYGGAMRPPLNALGGPGMPGMNMGPGGGRPWPNPTNANSGPPGGGGPPGTPIMPSPADSTNSGDNMYTLMNAVPPGPNRPNFPMGPGSDGPMGGLGGMESHHMNGSLGSGDMDSISKNSPNNMSLSNQPGTPRDDGEMGGNFLNPFQSESYSPSMTMSV", "length": 349, "header": "tr|A0A3Q1LYY1-1|F6R8M4_BOVIN Computationally mapped isoform of Single stranded DNA binding protein 2 OS=Bos taurus OX=9913 GN=SSBP2 PE=4 SV=1 CANONICAL=F6R8M4-1" }, "locus": { "chromosome": "7", "start_pos": 81711461, "end_pos": 81402176, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000086123.2", "url": "https://www.ensembl.org/id/ENSBTAT00000086123.2" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000062821.1", "url": "https://www.ensembl.org/id/ENSBTAP00000062821.1" } ] } }, { "isoform_ac": "A0A3Q1NGE0-1", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1NGE0/entry", "sequence": { "sequence": "MSWHQRPRLERQARLALYVYEYLLHVGAQKSAQTFLSEIRWEKNITLGEPPGFLHSWWCVFWDLYCAAPERRETCEHSSEAKAFHDYSAAAAPSPVLGNIPPGDGMPVGPVPPGFFQPFMSPRYPGGPRPPLRIPNQALGGVPGSQPLLPSGMDPTRQQGHPNMGGPMQRMTPPRGMVPLGPQNYGGAMRPPLNALGGPGMPGMNMGPGGGRPWPNPTNANSIPYSSASPGNYVGPPGGGGPPGTPIMPSPADSTNSGDNMYTLMNAVPPGPNRPNFPMGPGSDGPMGGLGGMESHHMNGSLGSGDMDSISKNSPNNMSLSNQPGTPRDDGEMGGNFLNPFQSESYSPSMTMSV", "length": 354, "header": "tr|A0A3Q1NGE0-1|F6R8M4_BOVIN Computationally mapped isoform of Single stranded DNA binding protein 2 OS=Bos taurus OX=9913 GN=SSBP2 PE=4 SV=2 CANONICAL=F6R8M4-1" }, "locus": { "chromosome": "7", "start_pos": 81712513, "end_pos": 81402176, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000071887.2", "url": "https://www.ensembl.org/id/ENSBTAT00000071887.2" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000070871.2", "url": "https://www.ensembl.org/id/ENSBTAP00000070871.2" } ] } }, { "isoform_ac": "A0AAA9RYF7-1", "url": "https://www.uniprot.org/uniprotkb/A0AAA9RYF7/entry", "sequence": { "sequence": "MRLALYVYEYLLHVGAQKSAQTFLSEIRWEKNITLGEPPGFLHSWWCVFWDLYCAAPERRETCEHSSEAKAFHDYSAAAAPSPVLGNIPPGDGMPVGPVPPGFFQPFMSPRYPGGPRPPLRIPNQALGGVPGSQPLLPSGMDPTRQQGHPNMGGPMQRMTPPRGMVPLGPQSDPWLSLQNYGGAMRPPLNALGGPGMPGMNMGPGGGRPWPNPTNANSIPYSSASPGNYVGPPGGGGPPGTPIMPSPADSTNSGDNMYTLMNAVPPGPNRPNFPMGPGSDGPMGGLGGMESHHMNGSLGSGDMDSISKNSPNNMSLSNQPGTPRDDGEMGGNFLNPFQSESYSPSMTMSV", "length": 350, "header": "tr|A0AAA9RYF7-1|F6R8M4_BOVIN Computationally mapped isoform of Single stranded DNA binding protein 2 OS=Bos taurus OX=9913 GN=SSBP2 PE=4 SV=2 CANONICAL=F6R8M4-1" }, "locus": { "chromosome": "7", "start_pos": 81786492, "end_pos": 81402176, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000123077.2", "url": "https://www.ensembl.org/id/ENSBTAT00000123077.2" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000076297.2", "url": "https://www.ensembl.org/id/ENSBTAP00000076297.2" } ] } }, { "isoform_ac": "A0AAA9TLT8-1", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TLT8/entry", "sequence": { "sequence": "MYGKGKSNSSAVPSDSQAREKLALYVYEYLLHVGAQKSAQTFLSEIRWEKNITLGEPPGFLHSWWCVFWDLYCAAPERRETCEHSSEAKAFHDYSAAAAPSPVLGNIPPGDGMPVGPVPPGFFQPFMSPRYPGGPRPPLRIPNQALGGVPGSQPLLPSGMDPTRQQGHPNMGGPMQRMTPPRGMVPLGPQNYGGAMRPPLNALGGPGMPGMNMGPGGGRPWPNPTNANSIPYSSASPGNYVGPPGGGGPPGTPIMPSPADSTNSGDNMYTLMNAVPPGPNRPNFPMGPGSDGPMGGLGGMESHHMNGSLGSGDMDSISKYSPSMTMSV", "length": 328, "header": "tr|A0AAA9TLT8-1|F6R8M4_BOVIN Computationally mapped isoform of Single stranded DNA binding protein 2 OS=Bos taurus OX=9913 GN=SSBP2 PE=4 SV=1 CANONICAL=F6R8M4-1" }, "locus": { "chromosome": "7", "start_pos": 81711461, "end_pos": 81402176, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000128016.1", "url": "https://www.ensembl.org/id/ENSBTAT00000128016.1" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000099394.1", "url": "https://www.ensembl.org/id/ENSBTAP00000099394.1" } ] } }, { "isoform_ac": "A0AAA9TP98-1", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TP98/entry", "sequence": { "sequence": "MYGKGKSNSSAVPSDSQAREKLALYVYEYLLHVGAQKSAQTFLSEIRWEKNITLGEPPGFLHSWWCVFWDLYCAAPERRETCEHSSEAKAFHDYPFMSPRYPGGPRPPLRIPNQALGGVPGSQPLLPSGMDPTRQQGHPNMGGPMQRMTPPRGMVPLGPQSDPWLSLQNYGGAMRPPLNALGGPGMPGMNMGPGGGRPWPNPTNANSIPYSSASPGNYVGPPGGGGPPGTPIMPSPADSTNSGDNMYTLMNAVPPGPNRPNFPMGPGSDGPMGGLGGMESHHMNGSLGSGDMDSISKNSPNNMSLSNQPGTPRDDGEMGGNFLNPFQSESYSPSMTMSV", "length": 339, "header": "tr|A0AAA9TP98-1|F6R8M4_BOVIN Computationally mapped isoform of Single stranded DNA binding protein 2 OS=Bos taurus OX=9913 GN=SSBP2 PE=4 SV=2 CANONICAL=F6R8M4-1" }, "locus": { "chromosome": "7", "start_pos": 81711461, "end_pos": 81402176, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000091277.2", "url": "https://www.ensembl.org/id/ENSBTAT00000091277.2" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000098180.2", "url": "https://www.ensembl.org/id/ENSBTAP00000098180.2" } ] } }, { "isoform_ac": "F6R8M4-1", "url": "https://www.uniprot.org/uniprotkb/F6R8M4/entry", "sequence": { "sequence": "MYGKGKSNSSAVPSDSQAREKLALYVYEYLLHVGAQKSAQTFLSEIRWEKNITLGEPPGFLHSWWCVFWDLYCAAPERRETCEHSSEAKAFHDYSAAAAPSPVLGNIPPGDGMPVGPVPPGFFQPFMSPRYPGGPRPPLRIPNQALGGVPGSQPLLPSGMDPTRQQGHPNMGGPMQRMTPPRGMVPLGPQSDPWLSLQNYGGAMRPPLNALGGPGMPGMNMGPGGGRPWPNPTNANSIPYSSASPGNYVGPPGGGGPPGTPIMPSPADSTNSGDNMYTLMNAVPPGPNRPNFPMGPGSDGPMGGLGGMESHHMNGSLGSGDMDSISKNSPNNMSLSNQPGTPRDDGEMGGNFLNPFQSESYSPSMTMSV", "length": 369, "header": "tr|F6R8M4-1|F6R8M4_BOVIN Isoform 1 of Single stranded DNA binding protein 2 OS=Bos taurus OX=9913 GN=SSBP2 PE=4 SV=1 CANONICAL=F6R8M4-1" }, "locus": { "chromosome": "7", "start_pos": 81711461, "end_pos": 81402176, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000018404.6", "url": "https://www.ensembl.org/id/ENSBTAT00000018404.6" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000018404.5", "url": "https://www.ensembl.org/id/ENSBTAP00000018404.5" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [], "orthologs": [], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 2, "go_terms": [ { "name": "nucleus", "id": "GO:0005634", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005634", "evidence": [ { "database": "UniProtKB", "id": "F6R8M4", "url": "https://www.uniprot.org/uniprotkb/F6R8M4" } ], "pmid": "" }, { "name": "nucleoplasm", "id": "GO:0005654", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005654", "evidence": [ { "database": "UniProtKB", "id": "F6R8M4", "url": "https://www.uniprot.org/uniprotkb/F6R8M4" } ], "pmid": "" } ] }, { "name": "Molecular Function", "total": 1, "go_terms": [ { "name": "single-stranded DNA binding", "id": "GO:0003697", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003697", "evidence": [ { "database": "UniProtKB", "id": "F6R8M4", "url": "https://www.uniprot.org/uniprotkb/F6R8M4" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 314, "end_pos": 316, "annotation": "n_glycosylation_sequon" }, { "start_pos": 332, "end_pos": 334, "annotation": "n_glycosylation_sequon" }, { "start_pos": 51, "end_pos": 53, "annotation": "n_glycosylation_sequon" }, { "start_pos": 8, "end_pos": 10, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 314, "end_pos": 316 }, { "start_pos": 332, "end_pos": 334 }, { "start_pos": 51, "end_pos": 53 }, { "start_pos": 8, "end_pos": 10 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ], "tool_support": { "graph_view": "yes" } }, { "uniprot_canonical_ac": "F1N6M1-1", "uniprot_ac": "F1N6M1", "uniprot_id": "F1N6M1_BOVIN", "mass": { "chemical_mass": 109963.0, "monoisotopic_mass": 109963.0 }, "refseq": {}, "gene_names": [ { "name": "ICE2", "type": "recommended", "evidence": [ { "id": "F1N6M1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1N6M1" } ] } ], "protein_names": [ { "name": "Interactor of little elongation complex ELL subunit 2", "type": "synonym", "evidence": [ { "id": "F1N6M1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1N6M1/entry#names_and_taxonomy" } ] } ], "function": [], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Bos taurus", "taxid": 9913, "evidence": [ { "database": "UniProtKB", "id": "F1N6M1", "url": "https://www.uniprot.org/uniprotkb/F1N6M1" } ], "common_name": "Bovine", "glygen_name": "Bovine", "reference_species": "Bos taurus [9913]" } ], "gene": [ { "name": "ICE2", "url": "https://www.uniprot.org/uniprotkb/F1N6M1", "locus": { "chromosome": "10", "start_pos": 49770689, "end_pos": 49707745, "strand": "-", "evidence": [ { "database": "Ensembl Gene", "id": "ENSBTAG00000005328", "url": "https://www.ensembl.org/id/ENSBTAG00000005328" } ] } } ], "crossref": [ { "id": "F1N6M1", "url": "https://alphafold.ebi.ac.uk/entry/F1N6M1", "database": "AlphaFoldDB", "categories": [] }, { "id": "ENSBTAG00000005328", "url": "https://bgee.org/?page=gene&gene_id=ENSBTAG00000005328", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "541255", "url": "https://www.ncbi.nlm.nih.gov/gene/541255", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR019535", "url": "https://www.ebi.ac.uk/interpro/entry/IPR019535", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "LPFHQQH", "url": "https://omabrowser.org/oma/group/LPFHQQH/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "A0A3Q1MIA8", "url": "https://www.orthodb.org/?gene=A0A3Q1MIA8", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "F1N6M1", "url": "https://www.orthodb.org/?gene=F1N6M1", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR14633", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR14633", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR14633:SF3", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR14633:SF3", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF10505", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF10505", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "R-BTA-6807505", "url": "https://www.reactome.org/PathwayBrowser/#R-BTA-6807505", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "A0A3Q1LNW3", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1LNW3", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A3Q1LNW3-1", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1LNW3-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A3Q1MIA8", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1MIA8", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A3Q1MIA8-1", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1MIA8-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0AAA9SPQ1", "url": "https://www.uniprot.org/uniprotkb/A0AAA9SPQ1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0AAA9SPQ1-1", "url": "https://www.uniprot.org/uniprotkb/A0AAA9SPQ1-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "F1N6M1", "url": "https://www.uniprot.org/uniprotkb/F1N6M1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "F1N6M1-1", "url": "https://www.uniprot.org/uniprotkb/F1N6M1-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MTSMMAMGEPRLNWDVSPKNGLKTFFSRENYKDQSMAPSLKELCILSSRRIGENLNASAGSVENEPTVNSAAQAKEKVKTTVGMVLLPKPRVPYPRFSRFSQREQRNYVDLLVKYAKVPPNSKTVGINKNDYLQYLEMKKHVNEEVTEFLKFLQNSAKKCAQDYNMLSDDACLVTEQILKACIEQVKKYPEFYTLHEVTSLMGFFPFRIEMGFKLEKTLLALGSVKYVKTVFPSMPAKLQLSKDTIPAIETPEQIAAAMHYDISEDPNAEKLVARYHPQIALTSQSLFTLLNNHGPSYKEQWEIPVCIQVIPVAGSKPIKVIYINSPLPQKKMTMRERNQIFHEVPLKFMMSKNTSVPVSAVFMDKPEEYISEMDISYEVNECRKIETLENLDLEFDDDVTELETFGATTTKPSKSPSPASTSTVAPMTDTLTAPSIADTSEAPTSPDISAHSRSLSQILMEQLQKEKQLVTGMIDSGPEESKNKDDQRFIPCGEKVSNSDKPLVQDSDLKTSDPLQLESSMEIETSSKNDMATEMESVDERVNVLENTDTNSKEKTVTSEAANTEDVVLDSSDTDEDCLIIDMECQSNSHGKTAEVGSNLSSKPASLNSSSGQTSTGNQTNSTCPEESCVLKKPIKRVYKKFDPVGEILKMQDELLKPISRKIPELPLMNSENSKQPPISEQPSAPSDACSWPKSIWPSAFQKPKGRLPYELQDYVEDTSEYVAPQEGNFVYKLFSLQDLLLLVRCSVQRIETRPRSKKRKKIRRQFPVYVLPKVEYQACYGVEALTESELCRLWTESLLHSNSSFYVGHIDAFTSKLFLLEEITSEELKEKLSALKISSLFNILQHILRKLSSLQEGSYLLSHAAEDSSLLIYKTSDGKVTRTAYNLHKTHCGLPGVPSSLSVPWVPLDPSLLLPYHIHHGRIPCTFPPKSLGPTAQQKIGGTRMPTRSHRNSVSVETKSLPAQQVENEGVASSKRKIT", "length": 981, "header": "tr|F1N6M1-1|F1N6M1_BOVIN Isoform 1 of Interactor of little elongation complex ELL subunit 2 OS=Bos taurus OX=9913 GN=ICE2 PE=4 SV=1 CANONICAL=F1N6M1-1" }, "isoforms": [ { "isoform_ac": "A0A3Q1LNW3-1", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1LNW3/entry", "sequence": { "sequence": "MTSMMAMGEPRLNWDVSPKNGLKTFFSRENYKDQSMAPSLKELCILSSRRIGENLNASAGSVENEPTVNSAAQAKEKVKTTVGMVLLPKPRVPYPRFSRFSQREQRNYVDLLVKYAKVPPNSKTVGINKNDYLQYLEMKKHVNEEVTEFLKFLQNSAKKCAQDYNMLSDDACLVTEQILKACIEQVKKYPEFYTLHEVTSLMGFFPFRIEMGFKLEKTLLALGSVKYVKTVFPSMPAKLQLSKDTIPAIETPEQIAAAMHYDISEDPNAEKLVARYHPQIALTSQSLFTLLNNHGPSYKEQWEIPVCIQVIPVAGSKPIKVIYINSPLPQKKMTMRERNQIFHEVPLKFMMSKNTSVPVSAVFMDKPEEYISEMDNHQRPNKIRGTYRTEIVKKTGIQISYEVNECRKIETLENLDLEFDDDVTELETFGATTTKPSKSPSPASTSTVAPMTDTLTAPSIADTSEAPTSPDISAHSRSLSQILMEQLQKEKQLVTGMIDSGPEESKNKDDQRFIPCGEKVSNSDKPLVQDSDLKTSDPLQLESSMEIETSSKNDMATEMESVDERVNVLENTDTNSKEKTVTSEAANTEDVVLDSSDTDEDCLIIDMECQSNSHGKTAEVGSNLSSKPASLNSSSGQTSTGNQTNSTCPEESCVLKKPIKRVYKKFDPVGEILKMQDELLKPISRKIPELPLMNSENSKQPPISEQPSAPSDACSWPKSIWPSAFQKPKGRLPYELQDYVEDTSEYVAPQEGNFVYKLFSLQDLLLLVRCSVQRIETRPRSKKRKKIRRQFPVYVLPKVEYQACYGVEALTESELCRLWTESLLHSNSSFYVGHIDAFTSKLFLLEEITSEELKEKLSALKISSLFNILQHILRKLSSLQEGSYLLSHAAEDSSLLIYKTSDGKVTRTAYNLHKTHCGLPGVPSSLSVPWVPLDPSLLLPYHIHHGRIPCTFPPKSLGPTAQQKIGGTRMPTRSHRNSVSVETKSLPAQQVENEGVASSKRKIT", "length": 1004, "header": "tr|A0A3Q1LNW3-1|F1N6M1_BOVIN Computationally mapped isoform of Interactor of little elongation complex ELL subunit 2 OS=Bos taurus OX=9913 GN=ICE2 PE=4 SV=1 CANONICAL=F1N6M1-1" }, "locus": { "chromosome": "10", "start_pos": 49770390, "end_pos": 49708901, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000085432.3", "url": "https://www.ensembl.org/id/ENSBTAT00000085432.3" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000058537.2", "url": "https://www.ensembl.org/id/ENSBTAP00000058537.2" } ] } }, { "isoform_ac": "A0A3Q1MIA8-1", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1MIA8/entry", "sequence": { "sequence": "MTSMMAMGEPRLNWDVSPKNGLKTFFSRENYKDQSMAPSLKELCILSSRRIGENLNASAGSVENEPTVNSAAQAKEKVKTTVGMVLLPKPRVPYPRFSRFSQREQRNYVDLLVKYAKVPPNSKTVGINKNDYLQYLEMKKHVNEEVTEFLKFLQNSAKKCAQDYNMLSDDACLVTEQILKACIEQVKKYPEFYTLHEVTSLMGFFPFRIEMGFKLEKTLLALGSVKYVKTVFPSMPAKLQLSKDTIPAIETPEQIAAAMHYDISEDPNAEKLVARYHPQIALTSQSLFTLLNNHGPSYKEQWEIPVCIQVIPVAGSKPIKVIYINSPLPQKKMTMRERNQIFHEVPLKFMMSKNTSVPVSAVFMDKPEEYISEMDSVFGNTPSILGREKISYEVNECRKIETLENLDLEFDDDVTELETFGATTTKPSKSPSPASTSTVAPMTDTLTAPSIADTSEAPTSPDISAHSRSLSQILMEQLQKEKQLVTGMIDSGPEESKNKDDQRFIPCGEKVSNSDKPLVQDSDLKTSDPLQLESSMEIETSSKNDMATEMESVDERVNVLENTDTNSKEKTVTSEAANTEDVVLDSSDTDEDCLIIDMECQSNSHGKTAEVGSNLSSKPASLNSSSGQTSTGNQTNSTCPEESCVLKKPIKRVYKKFDPVGEILKMQDELLKPISRKIPELPLMNSENSKQPPISEQPSAPSDACSWPKSIWPSAFQKPKGRLPYELQDYVEDTSEYVAPQEGNFVYKLFSLQDLLLLVRCSVQRIETRPRSKKRKKIRRQFPVYVLPKVEYQACYGVEALTESELCRLWTESLLHSNSSFYVGHIDAFTSKLFLLEEITSEELKEKLSALKISSLFNILQHILRKLSSLQEGSYLLSHAAEDSSLLIYKTSDGKVTRTAYNLHKTHCGLPGVPSSLSVPWVPLDPSLLLPYHIHHGRIPCTFPPKSLGPTAQQKIGGTRMPTRSHRNSVSVETKSLPAQQVENEGVASSKRKIT", "length": 995, "header": "tr|A0A3Q1MIA8-1|F1N6M1_BOVIN Computationally mapped isoform of Interactor of little elongation complex ELL subunit 2 OS=Bos taurus OX=9913 GN=ICE2 PE=4 SV=1 CANONICAL=F1N6M1-1" }, "locus": { "chromosome": "10", "start_pos": 49770390, "end_pos": 49708901, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000076013.3", "url": "https://www.ensembl.org/id/ENSBTAT00000076013.3" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000070996.1", "url": "https://www.ensembl.org/id/ENSBTAP00000070996.1" } ] } }, { "isoform_ac": "A0AAA9SPQ1-1", "url": "https://www.uniprot.org/uniprotkb/A0AAA9SPQ1/entry", "sequence": { "sequence": "SNSLMYATEDVSPKNGLKTFFSRENYKDQSMAPSLKELCILSSRRIGENLNASAGSVENEPTVNSAAQAKEKVKTTVGMVLLPKPRVPYPRFSRFSQREQRNYVDLLVKYAKVPPNSKTVGINKNDYLQYLEMKKHVNEEVTEFLKFLQNSAKKCAQDYNMLSDDACLVTEQILKACIEQVKKYPEFYTLHEVTSLMGFFPFRIEMGFKLEKTLLALGSVKYVKTVFPSMPAKLQLSKDTIPAIETPEQIAAAMHYDISEDPNAEKLVARYHPQIALTSQSLFTLLNNHGPSYKEQWEIPVCIQVIPVAGSKPIKVIYINSPLPQKKMTMRERNQIFHEVPLKFMMSKNTSVPVSAVFMDKPEEYISEMDISYEVNECRKIETLENLDLEFDDDVTELETFGATTTKPSKSPSPASTSTVAPMTDTLTAPSIADTSEAPTSPDISAHSRSLSQILMEQLQKEKQLVTGMIDSGPEESKNKDDQRFIPCGEKVSNSDKPLVQDSDLKTSDPLQLESSMEIETSSKNDMATEMESVDERVNVLENTDTNSKEKTVTSEAANTEDVVLDSSDTDEDCLIIDMECQSNSHGKTAEVGSNLSSKPASLNSSSGQTSTGNQTNSTCPEESCVLKKPIKRVYKKFDPVGEILKMQDELLKPISRKIPELPLMNSENSKQPPISEQPSAPSDACSWPKSIWPSAFQKPKGRLPYELQDYVEDTSEYVAPQEGNFVYKLFSLQDLLLLVRCSVQRIETRPRSKKRKKIRRQFPVYVLPKVEYQACYGVEALTESELCRLWTESLLHSNSSFYVGHIDAFTSKLFLLEEITSEELKEKLSALKISSLFNILQHILRKLSSLQEGSYLLSHAAEDSSLLIYKTSDGKVTRTAYNLHKTHCGLPGVPSSLSVPWVPLDPSLLLPYHIHHGRIPCTFPPKSLGPTAQQKIGGTRMPTRSHRNSVSVETKSLPAQQVENEGVASSKRKIT", "length": 976, "header": "tr|A0AAA9SPQ1-1|F1N6M1_BOVIN Computationally mapped isoform of Interactor of little elongation complex ELL subunit 2 OS=Bos taurus OX=9913 GN=ICE2 PE=4 SV=1 CANONICAL=F1N6M1-1" }, "locus": { "chromosome": "10", "start_pos": 49770390, "end_pos": 49710711, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000125076.2", "url": "https://www.ensembl.org/id/ENSBTAT00000125076.2" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000087341.1", "url": "https://www.ensembl.org/id/ENSBTAP00000087341.1" } ] } }, { "isoform_ac": "F1N6M1-1", "url": "https://www.uniprot.org/uniprotkb/F1N6M1/entry", "sequence": { "sequence": "MTSMMAMGEPRLNWDVSPKNGLKTFFSRENYKDQSMAPSLKELCILSSRRIGENLNASAGSVENEPTVNSAAQAKEKVKTTVGMVLLPKPRVPYPRFSRFSQREQRNYVDLLVKYAKVPPNSKTVGINKNDYLQYLEMKKHVNEEVTEFLKFLQNSAKKCAQDYNMLSDDACLVTEQILKACIEQVKKYPEFYTLHEVTSLMGFFPFRIEMGFKLEKTLLALGSVKYVKTVFPSMPAKLQLSKDTIPAIETPEQIAAAMHYDISEDPNAEKLVARYHPQIALTSQSLFTLLNNHGPSYKEQWEIPVCIQVIPVAGSKPIKVIYINSPLPQKKMTMRERNQIFHEVPLKFMMSKNTSVPVSAVFMDKPEEYISEMDISYEVNECRKIETLENLDLEFDDDVTELETFGATTTKPSKSPSPASTSTVAPMTDTLTAPSIADTSEAPTSPDISAHSRSLSQILMEQLQKEKQLVTGMIDSGPEESKNKDDQRFIPCGEKVSNSDKPLVQDSDLKTSDPLQLESSMEIETSSKNDMATEMESVDERVNVLENTDTNSKEKTVTSEAANTEDVVLDSSDTDEDCLIIDMECQSNSHGKTAEVGSNLSSKPASLNSSSGQTSTGNQTNSTCPEESCVLKKPIKRVYKKFDPVGEILKMQDELLKPISRKIPELPLMNSENSKQPPISEQPSAPSDACSWPKSIWPSAFQKPKGRLPYELQDYVEDTSEYVAPQEGNFVYKLFSLQDLLLLVRCSVQRIETRPRSKKRKKIRRQFPVYVLPKVEYQACYGVEALTESELCRLWTESLLHSNSSFYVGHIDAFTSKLFLLEEITSEELKEKLSALKISSLFNILQHILRKLSSLQEGSYLLSHAAEDSSLLIYKTSDGKVTRTAYNLHKTHCGLPGVPSSLSVPWVPLDPSLLLPYHIHHGRIPCTFPPKSLGPTAQQKIGGTRMPTRSHRNSVSVETKSLPAQQVENEGVASSKRKIT", "length": 981, "header": "tr|F1N6M1-1|F1N6M1_BOVIN Isoform 1 of Interactor of little elongation complex ELL subunit 2 OS=Bos taurus OX=9913 GN=ICE2 PE=4 SV=1 CANONICAL=F1N6M1-1" }, "locus": { "chromosome": "10", "start_pos": 49770390, "end_pos": 49708901, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000007009.6", "url": "https://www.ensembl.org/id/ENSBTAT00000007009.6" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000007009.4", "url": "https://www.ensembl.org/id/ENSBTAP00000007009.4" } ] } } ], "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "other", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 445, "start_aa": "Thr", "end_pos": 445, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr445", "evidence": [ { "id": "", "database": "GlyGen", "url": "https://data.glygen.org/" } ], "filter_code": "000000000000000010000.00000000001000.0.01000" } ], "phosphorylation": [], "glycation": [], "keywords": [ "glycoprotein", "glycoprotein_predicted" ], "publication": [], "pathway": [ { "id": "R-BTA-6807505", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-BTA-6807505", "resource": "Reactome", "description": "RNA polymerase II transcribes snRNA genes" } ], "orthologs": [ { "uniprot_canonical_ac": "D3ZIQ8-1", "protein_name": "Interactor of little elongation complex ELL subunit 2", "gene_name": "Ice2", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MSSGITMSEPRLNWDVTPKNGLKVFFSPENYKDHSMAPSLKELYILSNRRIGENVSVSANSVENEPAVSSATQAKEKVGMILLPKPRVPYPRFSRFSQREQRTFVDLLVKYAKIPSSSKTVGTNTNEFLQYLDMKKHVNEEVNEFLKFLQNSAKKCAQDYNMLSDEARLFTEQILRACIEQVKKYPEFYTLHEVTSLMGFFPFKIEMGLKLEKTLLVLGSAKFVKTAFPSMPVKLQLSKEDMSSIENPQQQAEAMHCDISKDPNAEKLVSRYHPQIALTSQALFTLLNNHGPSYKEQWEIPVCVQMIAVEGSKPVKVIYINSPLPRKQMTMRERNQIFHEVPLKHIFSKTTSVPVSAVFMDKPEEYTSEVDISTEASECRKIETLENLDLDFDGDVTELETFGVTTTSPSRSPSSESDSSAPIMTDVHTAPKVTAIPVAPAAPVTPAAPVAPVVAPVAPVVAPVAPAAPVTPVTPEASAIPNITDDSRSLCQILMKQLQKEKQLFSGVESGPEACKNKDDQGLEPCAEEGPSANAKSLTQDSEVHRTEEISNESDVGALCTSDERQSVQKNADNPNETATASETADTEKGIPCGSDTDEDCLIIDTESKSNSDGRTAGLGSSPNSSAQASVENQTTTTVSEESCVLKKPIKRVYKKFDPVGEILKMQDELLKPVSRTIPELPLTNSEESKQPSASEQPSATLDASTWPKSSWPSAFQKPKGRLPYELQDYVEDTSEYVAPQEGNFVYKLFSLQDLLLLVRCSVQRVETRPRSKKRKKIRRQFPVYVLPKVEYQGCYGVEALTESELCRFWTESLLHSNCSFYVGHIDAFTSKLFMLEEITSEELKEKLAALKISSLFNILQHILKKLCSLQEGSYLLSHAAEDSSLLIYKTSDGKVTRTAYNLHKAHCDLPGVPSSLSVPWVPLDPSYLLPYHIHHGRIPCTFPPKSLRPAAQPKVGATRMPTRNHRNPVSRETKSSCLPVQQVENEGVAQNKRKIM", "length": 997 }, "evidence": [ { "id": "F1N6M1", "url": "https://omabrowser.org/oma/group/F1N6M1/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "Q3UZ18-1", "protein_name": "Little elongation complex subunit 2", "gene_name": "Ice2", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MSSSITMSEPRLNWDVTPKNGLKAFFSPENYKDHSMAPSLKELYILSNRRIGENLSVSASSVENEPAVSSATQAKEKVGMILLPKPRVPYPRFSRFSQREQRTYVDLLAKYAKLPSSSKTVGTNTNEYLQYLDMKKHVNEEVNEFLKFLQNSAKKCAQDYNMLSDEARLFTEQLLRACIEQVKKYPEFYTLHEVTSLMGFFPFKTEMGLKLEKTLLVLGSAKFVKTAFPSMPVKLQLSKEDMSSIETPQQKAEVMHCDISKDPNAEKLVSRYHPQIALTSQALFTLLNNHGPSYKEQWEIPVCVEMIAVEGSKPVKVIYINSPLPRKQMTMRERNQIFHEVPLKHIISKNTSVPVSAVFMDKPEEYTSEVDMPTEAGECRKIETLENLDMDFDGDVTELETFGVTTTSPPRSPSSESDSSAPLMTDVHAVPKIAAVPLAPATPVAPTMPVAPATPVTPTMPMAPATPEASATPNITDDSRSLCQILMKQLQKEKQLFSGVEGGPEGCKNKDDQGLEPCGEEVPSANAKSLTQDNEVHRTEGISKESDVGVLCTNDERQGGQGNANNPNNTATASEAAESEKGIPCGSDTDEDCLIIDTESRSCDGKTADLGSRPNSSAQASAGNQATTTVSEESCVLKKPIKRVYKKFDPVGEILKMQDELLKPVSRKVPELPLTNSEESKQPPASEQPSAALDAAPWPKSSWPSAFQKPKGRLPYELQDYVEDTSEYIAPQEGNFVYKLFSLQDLLLLVRCSIQRVETRPRSKKRKKIRRQFPVYVLPKVEYQGCYGVEALTESELCRFWTESLLHSNCSFYVGHIDAFTSKLFMLEEIASEELKEKLAALKISSLFNILQHILKKLCSLQEGSYLLSHAAEDSSLLIYKTSDGKVTRTAYNLHKAHCDLPGVPSSLSVPWVPLDPSYLLPYHIHHGRVPCTFPPKPLRPAAQAKVGGTRMPTRNHRNPVSMETKSSCLPVQQVENEGVARNKRKIM", "length": 988 }, "evidence": [ { "id": "F1N6M1", "url": "https://omabrowser.org/oma/group/F1N6M1/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q659A1-1", "protein_name": "Little elongation complex subunit 2", "gene_name": "ICE2", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MSSKMVISEPGLNWDISPKNGLKTFFSRENYKDHSMAPSLKELRVLSNRRIGENLNASASSVENEPAVSSATQAKEKVKTTIGMVLLPKPRVPYPRFSRFSQREQRSYVDLLVKYAKIPANSKAVGINKNDYLQYLDMKKHVNEEVTEFLKFLQNSAKKCAQDYNMLSDDARLFTEKILRACIEQVKKYSEFYTLHEVTSLMGFFPFRVEMGLKLEKTLLALGSVKYVKTVFPSMPIKLQLSKDDIATIETSEQTAEAMHYDISKDPNAEKLVSRYHPQIALTSQSLFTLLNNHGPTYKEQWEIPVCIQVIPVAGSKPVKVIYINSPLPQKKMTMRERNQIFHEVPLKFMMSKNTSVPVSAVFMDKPEEFISEMDMSCEVNECRKIESLENLYLDFDDDVTELETFGVTTTKVSKSPSPASTSTVPNMTDAPTAPKAGTTTVAPSAPDISANSRSLSQILMEQLQKEKQLVTGMDGGPEECKNKDDQGFESCEKVSNSDKPLIQDSDLKTSDALQLENSQEIETSNKNDMTIDILHADGERPNVLENLDNSKEKTVGSEAAKTEDTVLCSSDTDEECLIIDTECKNNSDGKTAVVGSNLSSRPASPNSSSGQASVGNQTNTACSPEESCVLKKPIKRVYKKFDPVGEILKMQDELLKPISRKVPELPLMNLENSKQPSVSEQLSGPSDSSSWPKSGWPSAFQKPKGRLPYELQDYVEDTSEYLAPQEGNFVYKLFSLQDLLLLVRCSVQRIETRPRSKKRKKIRRQFPVYVLPKVEYQACYGVEALTESELCRLWTESLLHSNSSFYVGHIDAFTSKLFLLEEITSEELKEKLSALKISNLFNILQHILKKLSSLQEGSYLLSHAAEDSSLLIYKASDGKVTRTAYNLYKTHCGLPGVPSSLSVPWVPLDPSLLLPYHIHHGRIPCTFPPKSLDTTTQQKIGGTRMPTRSHRNPVSMETKSSCLPAQQVETEGVAPHKRKIT", "length": 982 }, "evidence": [ { "id": "F1N6M1", "url": "https://omabrowser.org/oma/group/F1N6M1/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" } ], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 4, "go_terms": [ { "name": "transcription elongation factor complex", "id": "GO:0008023", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008023", "evidence": [ { "database": "UniProtKB", "id": "F1N6M1", "url": "https://www.uniprot.org/uniprotkb/F1N6M1" } ], "pmid": "" }, { "name": "Cajal body", "id": "GO:0015030", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0015030", "evidence": [ { "database": "UniProtKB", "id": "F1N6M1", "url": "https://www.uniprot.org/uniprotkb/F1N6M1" } ], "pmid": "" }, { "name": "euchromatin", "id": "GO:0000791", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000791", "evidence": [ { "database": "UniProtKB", "id": "F1N6M1", "url": "https://www.uniprot.org/uniprotkb/F1N6M1" } ], "pmid": "" }, { "name": "histone locus body", "id": "GO:0035363", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0035363", "evidence": [ { "database": "UniProtKB", "id": "F1N6M1", "url": "https://www.uniprot.org/uniprotkb/F1N6M1" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 3, "go_terms": [ { "name": "positive regulation of transcription by RNA polymerase III", "id": "GO:0045945", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0045945", "evidence": [ { "database": "UniProtKB", "id": "F1N6M1", "url": "https://www.uniprot.org/uniprotkb/F1N6M1" } ], "pmid": "" }, { "name": "snRNA transcription by RNA polymerase II", "id": "GO:0042795", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0042795", "evidence": [ { "database": "UniProtKB", "id": "F1N6M1", "url": "https://www.uniprot.org/uniprotkb/F1N6M1" } ], "pmid": "" }, { "name": "snRNA transcription by RNA polymerase III", "id": "GO:0042796", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0042796", "evidence": [ { "database": "UniProtKB", "id": "F1N6M1", "url": "https://www.uniprot.org/uniprotkb/F1N6M1" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 354, "end_pos": 356, "annotation": "n_glycosylation_sequon" }, { "start_pos": 56, "end_pos": 58, "annotation": "n_glycosylation_sequon" }, { "start_pos": 600, "end_pos": 602, "annotation": "n_glycosylation_sequon" }, { "start_pos": 609, "end_pos": 611, "annotation": "n_glycosylation_sequon" }, { "start_pos": 619, "end_pos": 621, "annotation": "n_glycosylation_sequon" }, { "start_pos": 622, "end_pos": 624, "annotation": "n_glycosylation_sequon" }, { "start_pos": 804, "end_pos": 806, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [ { "pdb_id": "AF-F1N6M1-F1", "pdb_chain": "global", "start_pos": 1, "end_pos": 981, "overlap": "1.0", "method": "AlphaFold", "type": "alphafold", "resolution": -1.0, "url": "https://data.glygen.org/ln2downloads/pdb/current/AF-F1N6M1-F1.pdb", "url_external": "https://alphafold.ebi.ac.uk/entry/F1N6M1" } ], "lectin_list": [], "domain_list": [], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" }, { "name": "homologset.oma", "label": "OMA Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [ 445 ], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 354, "end_pos": 356 }, { "start_pos": 56, "end_pos": 58 }, { "start_pos": 600, "end_pos": 602 }, { "start_pos": 609, "end_pos": 611 }, { "start_pos": 619, "end_pos": 621 }, { "start_pos": 622, "end_pos": 624 }, { "start_pos": 804, "end_pos": 806 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 1 }, { "field": "total_sites", "count": 1 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 1 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "exact_sites", "count": 1 }, { "field": "exact_o_linked_sites", "count": 1 }, { "field": "fuzzy_sites", "count": 0 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_pos", "start_aa", "end_pos", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 1 }, { "field": "total_sites", "count": 1 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 1 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "exact_sites", "count": 1 }, { "field": "exact_o_linked_sites", "count": 1 }, { "field": "fuzzy_sites", "count": 0 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_pos", "start_aa", "end_pos", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ], "tool_support": { "graph_view": "yes" } }, { "uniprot_canonical_ac": "F6Q807-1", "uniprot_ac": "F6Q807", "uniprot_id": "F6Q807_BOVIN", "mass": { "chemical_mass": 97309.0, "monoisotopic_mass": 97309.0 }, "refseq": {}, "gene_names": [ { "name": "HNRNPUL1", "type": "recommended", "evidence": [ { "id": "F6Q807", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F6Q807" } ] } ], "protein_names": [ { "name": "Heteroous nuclear ribonucleoprotein U like 1", "type": "synonym", "evidence": [ { "id": "F6Q807", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F6Q807/entry#names_and_taxonomy" } ] } ], "function": [], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Bos taurus", "taxid": 9913, "evidence": [ { "database": "UniProtKB", "id": "F6Q807", "url": "https://www.uniprot.org/uniprotkb/F6Q807" } ], "common_name": "Bovine", "glygen_name": "Bovine", "reference_species": "Bos taurus [9913]" } ], "gene": [ { "name": "HNRNPUL1", "url": "https://www.uniprot.org/uniprotkb/F6Q807", "locus": { "chromosome": "18", "start_pos": 50474318, "end_pos": 50439182, "strand": "-", "evidence": [ { "database": "Ensembl Gene", "id": "ENSBTAG00000003168", "url": "https://www.ensembl.org/id/ENSBTAG00000003168" } ] } } ], "crossref": [ { "id": "F6Q807", "url": "https://alphafold.ebi.ac.uk/entry/F6Q807", "database": "AlphaFoldDB", "categories": [] }, { "id": "ENSBTAG00000003168", "url": "https://bgee.org/?page=gene&gene_id=ENSBTAG00000003168", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "cd12884", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd12884", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "533197", "url": "https://www.ncbi.nlm.nih.gov/gene/533197", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR001870", "url": "https://www.ebi.ac.uk/interpro/entry/IPR001870", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR003034", "url": "https://www.ebi.ac.uk/interpro/entry/IPR003034", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR003877", "url": "https://www.ebi.ac.uk/interpro/entry/IPR003877", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR013320", "url": "https://www.ebi.ac.uk/interpro/entry/IPR013320", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR027417", "url": "https://www.ebi.ac.uk/interpro/entry/IPR027417", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR035778", "url": "https://www.ebi.ac.uk/interpro/entry/IPR035778", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR036361", "url": "https://www.ebi.ac.uk/interpro/entry/IPR036361", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR043136", "url": "https://www.ebi.ac.uk/interpro/entry/IPR043136", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "A0A3Q1LP65", "url": "https://www.orthodb.org/?gene=A0A3Q1LP65", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR12381", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR12381", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR12381:SF41", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR12381:SF41", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00622", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00622", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF02037", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF02037", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF13671", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF13671", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "A0A3Q1LP65", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1LP65", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A3Q1LP65-1", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1LP65-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0AAA9S748", "url": "https://www.uniprot.org/uniprotkb/A0AAA9S748", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0AAA9S748-1", "url": "https://www.uniprot.org/uniprotkb/A0AAA9S748-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0AAA9SMU2", "url": "https://www.uniprot.org/uniprotkb/A0AAA9SMU2", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0AAA9SMU2-1", "url": "https://www.uniprot.org/uniprotkb/A0AAA9SMU2-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "F6Q807", "url": "https://www.uniprot.org/uniprotkb/F6Q807", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "F6Q807-1", "url": "https://www.uniprot.org/uniprotkb/F6Q807-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MDVRRLKVNELREELQRRGLDTRGLKAELAERLQAALEAEEPDDERELEADDEPGRPGHNNEEVETEGGSELEGTAQPPPPGLQPHPEPGGYSGPDGHYVMDNITMQNQFYETQVIKQENESGYERRPLEIDQQQQAYRPEVKTEMKQEAPTSFLPPEASQHKPDRQQFQSRKRPYEENRGRGYFEHREDRRGRSPQPPAEEDEDDFDDTLVAIDTYNCDLHFKVARDRSSGYPLTIEGFAYLWSGARASYGVRRGRVCFEMKINEEISVKHLPSTEPDPHVVRIGWSLDSCSTQLGEEPFSYGYGGTGKKSTNSRFENYGDKFAENDVIGCFADFECGNDVELSFTKNGKWMGIAFRIQKEALGGQALYPHVLVKNCAVEFNFGQRAEPYCSVLPGFTFIQHLPLSERIRGTVGPKSKAECEILMMVGLPAAGKTTWAIKHAASNPSKKYNILGTNAIMDKMRVMGLRRQRNYAGRWDVLIQQATQCLNRLIQIAARKKRNYILDQTNVYGSAQRRKMRPFEGFQRKAIVICPTDEDLKDRTIKRTDEEGKDVPDHAVLEMKANFTLPDVGDFLDEVLFIELQREEADKLVRQYNEEGRRAGPPPEKRFDNRGGGGFRGRGGGGGFQRYDNRGPPGGNRGGFQNRGGGSGGGGNYRGGFNRSGGGGYNQNRWGNNNRDNNNSNNRGSYNRAPQQQPPPQQPPPPQPPPQQPPPPPTYSPARNPPGASGYNKNSNIPGSSANTSTPPVSSYSPPQRPGFLFPSTFQPSYSQPPPYNQGGYSQGYTAPPPPPPPPPAYNYGSYGGYNPAPYTPPPPPAAQTYPQPSYNQYQQYAQQWNQYYQNQGQWPPYYGNYDYGSYSGNTQGGTSTQ", "length": 869, "header": "tr|F6Q807-1|F6Q807_BOVIN Isoform 1 of Heteroous nuclear ribonucleoprotein U like 1 OS=Bos taurus OX=9913 GN=HNRNPUL1 PE=1 SV=1 CANONICAL=F6Q807-1" }, "isoforms": [ { "isoform_ac": "A0A3Q1LP65-1", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1LP65/entry", "sequence": { "sequence": "MDVRRLKVNELREELQRRGLDTRGLKAELAERLQAALEAEEPDDERELEADDEPGRPGHNNEEVETEGGSELEGTAQPPPPGLQPHPEPGGYSGPDGHYVMDNITMQNQFYETQVIKQENESGYERRPLEIDQQQQAYRPEVKTEMKQEAPTSFLPPEASQHKPDRQQFQSRKRPYEENRGRGYFEHREDRRGRSPQPPAEEDEDDFDDTLVAIDTYNCDLHFKVARDRSSGYPLTIEGFAYLWSGARASYGVRRGRVCFEMKINEEISVKHLPSTEPDPHVVRIGWSLDSCSTQLGEEPFSYGYGGTGKKSTNSRFENYGDKFAENDVIGCFADFECGNDVELSFTKNGKWMGIAFRIQKEALGGFTFIQHLPLSERIRGTVGPKSKAECEILMMVGLPAAGKTTWAIKHAASNPSKKYNILGTNAIMDKMRVMGLRRQRNYAGRWDVLIQQATQCLNRLIQIAARKKRNYILDQTNVYGSAQRRKMRPFEGFQRKAIVICPTDEDLKDRTIKRTDEEGKDVPDHAVLEMKANFTLPDVGDFLDEVLFIELQREEADKLGATEEASKIEEEAAVEEATTEEVSTAVEVVATTRTAGVTTTGTTTTPTTEAATTGPPSNSLRHSSHRHHSRHHSSLHRHPPTALLGTPQGPAATTRTATSLVQAPIPAPLLSAATALHSRVTASHLPTTREGTARATQPRHLHLRHHLPTTMGAMAATIQPLTPHHRPQRHRPTLSPAITSINSTPSSGTSTIRTRASGRHTTGTMTTGATPGTHRGAQAHSSHVSWRPLPASSTSAHLSPPHPSLPGPVVLGDGSSQGCLPSEGLFPHTGPGISSGFKQATMTFYFLFAPLPSSSSLPPFLLFD", "length": 865, "header": "tr|A0A3Q1LP65-1|F6Q807_BOVIN Computationally mapped isoform of Heteroous nuclear ribonucleoprotein U like 1 OS=Bos taurus OX=9913 GN=HNRNPUL1 PE=1 SV=1 CANONICAL=F6Q807-1" }, "locus": { "chromosome": "18", "start_pos": 50473531, "end_pos": 50440883, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000081408.3", "url": "https://www.ensembl.org/id/ENSBTAT00000081408.3" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000061856.1", "url": "https://www.ensembl.org/id/ENSBTAP00000061856.1" } ] } }, { "isoform_ac": "A0AAA9S748-1", "url": "https://www.uniprot.org/uniprotkb/A0AAA9S748/entry", "sequence": { "sequence": "MGSWEERGSRTWARGGVSGLEPTGPHVMDNITMQNQFYETQVIKQENESGYERRPLEIDQQQQAYRPEVKTEMKQEAPTSFLPPEASQHKPDRQQFQSRKRPYEENRGRGYFEHREDRRGRSPQPPAEEDEDDFDDTLVAIDTYNCDLHFKVARDRSSGYPLTIEGFAYLWSGARASYGVRRGRVCFEMKINEEISVKHLPSTEPDPHVVRIGWSLDSCSTQLGEEPFSYGYGGTGKKSTNSRFENYGDKFAENDVIGCFADFECGNDVELSFTKNGKWMGIAFRIQKEALGGQALYPHVLVKNCAVEFNFGQRAEPYCSVLPGFTFIQHLPLSERIRGTVGPKSKAECEILMMVGLPAAGKTTWAIKHAASNPSKKYNILGTNAIMDKMRVMGLRRQRNYAGRWDVLIQQATQCLNRLIQIAARKKRNYILDQTNVYGSAQRRKMRPFEGFQRKAIVICPTDEDLKDRTIKRTDEEGKDVPDHAVLEMKANFTLPDVGDFLDEVLFIELQREEADKLVRQYNEEGRRAGPPPEKRFDNRGGGGFRGRGGGGGFQRYDNRGPPGGNRGGFQNRGGGSGGGGNYRGGFNRSGGGGYNQNRWGNNNRDNNNSNNRGSYNRAPQQQPPPQQPPPPQPPPQQPPPPPTYSPARNPPGASGYNKNSNIPGSSANTSTPPVSSYSPPQPSYSQPPPYNQGGYSQGYTAPPPPPPPPPAYNYGSYGGYNPAPYTPPPPPAAQTYPQPSYNQYQQYAQQWNQYYQNQGQWPPYYGNYDYGSYSGNTQGGTSTQ", "length": 785, "header": "tr|A0AAA9S748-1|F6Q807_BOVIN Computationally mapped isoform of Heteroous nuclear ribonucleoprotein U like 1 OS=Bos taurus OX=9913 GN=HNRNPUL1 PE=1 SV=1 CANONICAL=F6Q807-1" }, "locus": { "chromosome": "18", "start_pos": 50473281, "end_pos": 50439202, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000135962.2", "url": "https://www.ensembl.org/id/ENSBTAT00000135962.2" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000079132.1", "url": "https://www.ensembl.org/id/ENSBTAP00000079132.1" } ] } }, { "isoform_ac": "A0AAA9SMU2-1", "url": "https://www.uniprot.org/uniprotkb/A0AAA9SMU2/entry", "sequence": { "sequence": "MDVRRLKVNELREELQRRGLDTRGLKAELAERLQPPPPGLQPHPEPGGYSGPDGHYVMDNITMQNQFYETQVIKQENESGYERRPLEIDQQQQAYRPEVKTEMKQEAPTSFLPPEASQHKPDRQQFQSRKRPYEENRGRGYFEHREDRRGRSPQPPAEEDEDDFDDTLVAIDTYNCDLHFKVARDRSSGYPLTIEGFAYLWSGARASYGVRRGRVCFEMKDFECGNDVELSFTKNGKWMGIAFRIQKEALGGQALYPHVLVKNCAVEFNFGQRAEPYCSVLPGFTFIQHLPLSERIRGTVGPKSKAECEILMMVGLPAAGKTTWAIKHAASNPSKKYNILGTNAIMDKMRVMGLRRQRNYAGRWDVLIQQATQCLNRLIQIAARKKRNYILDQTNVYGSAQRRKMRPFEGFQRKAIVICPTDEDLKDRTIKRTDEEGKDVPDHAVLEMKANFTLPDVGDFLDEVLFIELQREEADKLVRQYNEEGRRAGPPPEKRFDNRGGGGFRGRGGGGGFQRYDNRGPPGGNRGGFQNRGGGSGGGGNYRGGFNRSGGGGYNQNRWGNNNRDNNNSNNRGSYNRAPQQQPPPQQPPPPQPPPQQPPPPPTYSPARNPPGASGYNKNSNIPGSSANTSTPPVSSYSPPQRPGFLFPSTFQPSYSQPPPYNQGGYSQGYTAPPPPPPPPPAYNYGSYGGYNPAPYTPPPPPAAQTYPQPSYNQYQQYAQQWNQYYQNQGQWPPYYGNYDYGSYSGNTQGGTSTQ", "length": 755, "header": "tr|A0AAA9SMU2-1|F6Q807_BOVIN Computationally mapped isoform of Heteroous nuclear ribonucleoprotein U like 1 OS=Bos taurus OX=9913 GN=HNRNPUL1 PE=1 SV=1 CANONICAL=F6Q807-1" }, "locus": { "chromosome": "18", "start_pos": 50473281, "end_pos": 50440883, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000102271.2", "url": "https://www.ensembl.org/id/ENSBTAT00000102271.2" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000086629.1", "url": "https://www.ensembl.org/id/ENSBTAP00000086629.1" } ] } }, { "isoform_ac": "F6Q807-1", "url": "https://www.uniprot.org/uniprotkb/F6Q807/entry", "sequence": { "sequence": "MDVRRLKVNELREELQRRGLDTRGLKAELAERLQAALEAEEPDDERELEADDEPGRPGHNNEEVETEGGSELEGTAQPPPPGLQPHPEPGGYSGPDGHYVMDNITMQNQFYETQVIKQENESGYERRPLEIDQQQQAYRPEVKTEMKQEAPTSFLPPEASQHKPDRQQFQSRKRPYEENRGRGYFEHREDRRGRSPQPPAEEDEDDFDDTLVAIDTYNCDLHFKVARDRSSGYPLTIEGFAYLWSGARASYGVRRGRVCFEMKINEEISVKHLPSTEPDPHVVRIGWSLDSCSTQLGEEPFSYGYGGTGKKSTNSRFENYGDKFAENDVIGCFADFECGNDVELSFTKNGKWMGIAFRIQKEALGGQALYPHVLVKNCAVEFNFGQRAEPYCSVLPGFTFIQHLPLSERIRGTVGPKSKAECEILMMVGLPAAGKTTWAIKHAASNPSKKYNILGTNAIMDKMRVMGLRRQRNYAGRWDVLIQQATQCLNRLIQIAARKKRNYILDQTNVYGSAQRRKMRPFEGFQRKAIVICPTDEDLKDRTIKRTDEEGKDVPDHAVLEMKANFTLPDVGDFLDEVLFIELQREEADKLVRQYNEEGRRAGPPPEKRFDNRGGGGFRGRGGGGGFQRYDNRGPPGGNRGGFQNRGGGSGGGGNYRGGFNRSGGGGYNQNRWGNNNRDNNNSNNRGSYNRAPQQQPPPQQPPPPQPPPQQPPPPPTYSPARNPPGASGYNKNSNIPGSSANTSTPPVSSYSPPQRPGFLFPSTFQPSYSQPPPYNQGGYSQGYTAPPPPPPPPPAYNYGSYGGYNPAPYTPPPPPAAQTYPQPSYNQYQQYAQQWNQYYQNQGQWPPYYGNYDYGSYSGNTQGGTSTQ", "length": 869, "header": "tr|F6Q807-1|F6Q807_BOVIN Isoform 1 of Heteroous nuclear ribonucleoprotein U like 1 OS=Bos taurus OX=9913 GN=HNRNPUL1 PE=1 SV=1 CANONICAL=F6Q807-1" }, "locus": { "chromosome": "18", "start_pos": 50473281, "end_pos": 50440883, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000004114.7", "url": "https://www.ensembl.org/id/ENSBTAT00000004114.7" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000004114.5", "url": "https://www.ensembl.org/id/ENSBTAP00000004114.5" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [], "orthologs": [], "go_annotation": { "categories": [ { "name": "Molecular Function", "total": 2, "go_terms": [ { "name": "RNA binding", "id": "GO:0003723", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003723", "evidence": [ { "database": "UniProtKB", "id": "F6Q807", "url": "https://www.uniprot.org/uniprotkb/F6Q807" } ], "pmid": "" }, { "name": "enzyme binding", "id": "GO:0019899", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0019899", "evidence": [ { "database": "UniProtKB", "id": "F6Q807", "url": "https://www.uniprot.org/uniprotkb/F6Q807" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 4, "go_terms": [ { "name": "nucleus", "id": "GO:0005634", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005634", "evidence": [ { "database": "UniProtKB", "id": "F6Q807", "url": "https://www.uniprot.org/uniprotkb/F6Q807" } ], "pmid": "" }, { "name": "ribonucleoprotein complex", "id": "GO:1990904", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:1990904", "evidence": [ { "database": "UniProtKB", "id": "F6Q807", "url": "https://www.uniprot.org/uniprotkb/F6Q807" } ], "pmid": "" }, { "name": "nucleoplasm", "id": "GO:0005654", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005654", "evidence": [ { "database": "UniProtKB", "id": "F6Q807", "url": "https://www.uniprot.org/uniprotkb/F6Q807" } ], "pmid": "" }, { "name": "synapse", "id": "GO:0045202", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0045202", "evidence": [ { "database": "UniProtKB", "id": "F6Q807", "url": "https://www.uniprot.org/uniprotkb/F6Q807" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 2, "go_terms": [ { "name": "DNA-templated transcription", "id": "GO:0006351", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006351", "evidence": [ { "database": "UniProtKB", "id": "F6Q807", "url": "https://www.uniprot.org/uniprotkb/F6Q807" } ], "pmid": "" }, { "name": "alternative mRNA splicing, via spliceosome", "id": "GO:0000380", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000380", "evidence": [ { "database": "UniProtKB", "id": "F6Q807", "url": "https://www.uniprot.org/uniprotkb/F6Q807" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 103, "end_pos": 105, "annotation": "n_glycosylation_sequon" }, { "start_pos": 120, "end_pos": 122, "annotation": "n_glycosylation_sequon" }, { "start_pos": 565, "end_pos": 567, "annotation": "n_glycosylation_sequon" }, { "start_pos": 661, "end_pos": 663, "annotation": "n_glycosylation_sequon" }, { "start_pos": 681, "end_pos": 683, "annotation": "n_glycosylation_sequon" }, { "start_pos": 742, "end_pos": 744, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "F6Q807", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F6Q807" }, { "id": "PS50188", "database": "PROSITE", "url": "https://prosite.expasy.org/PS50188" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "B30.2/SPRY", "eco_id": "ECO_0000259", "start_pos": 192, "end_pos": 389, "start_aa": "Arg", "end_aa": "Glu", "glycosite_overlap": [] }, { "evidence": [ { "id": "F6Q807", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F6Q807" }, { "id": "PS50800", "database": "PROSITE", "url": "https://prosite.expasy.org/PS50800" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "SAP", "eco_id": "ECO_0000259", "start_pos": 3, "end_pos": 37, "start_aa": "Val", "end_aa": "Leu", "glycosite_overlap": [] } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 103, "end_pos": 105 }, { "start_pos": 120, "end_pos": 122 }, { "start_pos": 565, "end_pos": 567 }, { "start_pos": 661, "end_pos": 663 }, { "start_pos": 681, "end_pos": 683 }, { "start_pos": 742, "end_pos": 744 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": 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"n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ], "tool_support": { "graph_view": "yes" } }, { "uniprot_canonical_ac": "F1N3Y1-1", "uniprot_ac": "F1N3Y1", "uniprot_id": "F1N3Y1_BOVIN", "mass": { "chemical_mass": 99942.0, "monoisotopic_mass": 99942.0 }, "refseq": { "ac": "XP_005205878", "name": "TRPM8 channel-associated factor 2 isoform X1", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_005205878" }, "gene_names": [ { "name": "TCAF2", "type": "recommended", "evidence": [ { "id": "F1N3Y1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1N3Y1" } ] }, { "name": "FAM115C", "type": "synonym", "evidence": [ { "id": "XP_005205878", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_005205878" } ] }, { "name": "TCAF2", "type": "synonym", "evidence": [ { "id": "XP_005205878", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_005205878" } ] } ], "protein_names": [ { "name": "TRPM8 channel associated factor 2", "type": "synonym", "evidence": [ { "id": "F1N3Y1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1N3Y1/entry#names_and_taxonomy" } ] }, { "name": "TRPM8 channel-associated factor 2 isoform X1", "type": "synonym", "evidence": [ { "id": "XP_005205878", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_005205878" } ] } ], "function": [], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Bos taurus", "taxid": 9913, "evidence": [ { "database": "UniProtKB", "id": "F1N3Y1", "url": "https://www.uniprot.org/uniprotkb/F1N3Y1" } ], "common_name": "Bovine", "glygen_name": "Bovine", "reference_species": "Bos taurus [9913]" } ], "gene": [ { "name": "TCAF2", "url": "https://www.uniprot.org/uniprotkb/F1N3Y1", "locus": { "chromosome": "4", "start_pos": 106983187, "end_pos": 106998346, "strand": "+", "evidence": [ { "database": "Ensembl Gene", "id": "ENSBTAG00000005475", "url": "https://www.ensembl.org/id/ENSBTAG00000005475" } ] } } ], "crossref": [ { "id": "F1N3Y1", "url": "https://alphafold.ebi.ac.uk/entry/F1N3Y1", "database": "AlphaFoldDB", "categories": [] }, { "id": "ENSBTAG00000005475", "url": "https://bgee.org/?page=gene&gene_id=ENSBTAG00000005475", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "510320", "url": "https://www.ncbi.nlm.nih.gov/gene/510320", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR029062", "url": "https://www.ebi.ac.uk/interpro/entry/IPR029062", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR031161", "url": "https://www.ebi.ac.uk/interpro/entry/IPR031161", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR035423", "url": "https://www.ebi.ac.uk/interpro/entry/IPR035423", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR042279", "url": "https://www.ebi.ac.uk/interpro/entry/IPR042279", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR051244", "url": "https://www.ebi.ac.uk/interpro/entry/IPR051244", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "SCEATML", "url": "https://omabrowser.org/oma/group/SCEATML/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "F1N3Y1", "url": "https://www.orthodb.org/?gene=F1N3Y1", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR15730", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR15730", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR15730:SF4", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR15730:SF4", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF13402", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF13402", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF17291", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF17291", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF27016", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF27016", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF27027", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF27027", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "XP_005205878", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_005205878", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A3Q1LP76", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1LP76", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A3Q1LP76-1", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1LP76-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A3Q1M013", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1M013", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A3Q1M013-1", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1M013-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "F1N3Y1", "url": "https://www.uniprot.org/uniprotkb/F1N3Y1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "F1N3Y1-1", "url": "https://www.uniprot.org/uniprotkb/F1N3Y1-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MATTPAAAFEALMDGVTSWELPEGPVPSELLLTGEAAFPVMVNDKGQVLIAASFYGRGRLVVVSHEGYLLDAGLARFLLNAVRWLSPSPGAPVGVHPSLASLAHILEGSGVEAQVHPEPAEPLGVYCISAYNDTMTAELIQFVKRGGGLLIGGQAWHWASQHGSDQVLSEFPGNQVTSVAGVYFTDTYGVKGRFKVSKKVPKIPLQVRCGEDLRQDQQQLLEGISELDIGTKGLPSQLLVHGALAFPLGLDASLRCFLAAARYGRGRVVLAAHEGMLSAPSLGPFLLNAVRWLAKGQTGKVGVNTSLEKLHTLLLEHGLECSLEPHLTSGVCVYCCTAYSDKEAKQLQEFVAEGGGLLIGGHAWWWASQNPGRSALADFPGNVILNSFGLSILPWTLDPGCFPVPSADSLNYHFRKALSEFQATLNLEGGNLEKNWLAKLRVDGAAFLQIPAEGVPAYASLHRLLRKQLRLRLSGFPAVSRENPVAGDSCEAVVLCLATELARSGTDCSELAQGLGAWSCSSNLCPSEHTVEINARNPSDDAWMSTGLYLPNGQLTEVCLCEAAACAGLKLQIGCHTDNLMSASKLSRAPVVTHQCHMDRTEQLVSNLWGGLLYVIVPTGCNLGPMSITIKRAVPAPYYKLGETSLEAWRSCIQESPAPWGELATDNIILTVPTADLRALEDPEPLLRLWDEMMEAIARLAAQPFPFRRPERIVADVQISAGWMHSGYPIMCHLESVSELIDETGMRSRGLWGPVHELGHNQQREQWEFPPHTTEATCNLWSVYVHETVLGIPRAQAHPALSPPERENRIKTHLEKGAPLCDWKVWTALETYLQLQEAFGWEPFTQLFAEYQTLSDIPNDNPGKMNLWVRKFSEKVQKNLAPFFEAWGWPVEKEVASSLACLPEWEENPMRMYI", "length": 914, "header": "tr|F1N3Y1-1|F1N3Y1_BOVIN Isoform 1 of TRPM8 channel associated factor 2 OS=Bos taurus OX=9913 GN=TCAF2 PE=3 SV=2 CANONICAL=F1N3Y1-1" }, "isoforms": [ { "isoform_ac": "A0A3Q1LP76-1", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1LP76/entry", "sequence": { "sequence": "MATTPAAAFEALMDGVTSWELPEGPVPSELLLTGEAAFPVMVNDKGQVLIAASFYGRGRLVVVSHEGYLLDAGLARFLLNAVRWLSPSPGAPVGVHPSLASLAHILEGSGVEAQVHPEPAEPLGVYCISAYNDTMTAELIQFVKRGGGLLIGGQAWHWASQHGSDQVLSEFPGNQVTSVAGVYFTDTYGVKGRFKVSKKVPKIPLQVRCGEDLRQDQQQLLEGISELDIGTKGLPSQLLVHGALAFPLGLDASLRCFLAAARYGRGRVVLAAHEGMLSAPSLGPFLLNAVRWLAKGQTGKVGVNTSLEKLHTLLLEHGLECSLEPHLTSGVCVYCCTAYSDKEAKQLQEFVAEGGGLLIGGHAWWWASQNPGRSALADFPGNVILNSFGLSILPWTLDPGCFPVPSADSLNYHFRKALSEFQATLNLEGGNLEKNWLAKLRVDGAAFLQIPAEGVPAYASLHRLLRKQLRLRLSGFPAVSRENPVAGDSCEAVVLCLATELARSGTDCSELAQGLGAWSCSSNLCPSEHTVEINARNPSDDAWMSTGLYLPNGQLTEVCLCEAAACAGLKLQIGCHTDNLMSASKLSRAPVVTHQCHMDRTEQLVSNLWGGLLYVIVPTGCNLGPMSITIKRAVPAPYYKLGETSLEAWRSCIQESPAPWGELATDNIILTVPTADLRALEDPEPLLRLWDEMMEAIARLAAQPFPFRRPERIVADVQISAGWMHSGYPIMCHLESVSELIDETGMRSRGLWGPVHELGHNQQREQWEFPPHTTEATCNLWSVYVHETVLGIPRAQAHPALSPPERENRIKTHLEKGAPLCDWKVWTALETYLQI", "length": 835, "header": "tr|A0A3Q1LP76-1|F1N3Y1_BOVIN Computationally mapped isoform of TRPM8 channel associated factor 2 OS=Bos taurus OX=9913 GN=TCAF2 PE=3 SV=1 CANONICAL=F1N3Y1-1" }, "locus": { "chromosome": "4", "start_pos": 106998335, "end_pos": 106987822, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000075667.2", "url": "https://www.ensembl.org/id/ENSBTAT00000075667.2" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000056692.1", "url": "https://www.ensembl.org/id/ENSBTAP00000056692.1" } ] } }, { "isoform_ac": "A0A3Q1M013-1", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1M013/entry", "sequence": { "sequence": "MATTPAAAFEALMDGVTSWELPEGPVPSELLLTGEAAFPVMVNDKGQVLIAASFYGRGRLVVVSHEGYLLDAGLARFLLNAVRWLSPSPGAPVGVHPSLASLAHILEGSGVEAQVHPEPAEPLGVYCISAYNDTMTAELIQFVKRGGGLLIGGQAWHWASQHGSDQVLSEFPGNQVTSVAGVYFTDTYGVKGRFKVSKKVPKIPLQVRCGEDLRQDQQQLLEGISELDIGTKGLPSQLLVHGALAFPLGLDASLRCFLAAARYGRGRVVLAAHEGMLSAPSLGPFLLNAVRWLAKGQTGKVGVNTSLEKLHTLLLEHGLECSLEPHLTSGVCVYCCTAYSDKEAKQLQEFVAEGGGLLIGGHAWWWASQNPGRSALADFPGNVILNSFGLSILPWTLDPGCFPVPSADSLNYHFRKALSEFQATLNLEGGNLEKNWLAKLRVDGAAFLQIPAEGVPAYASLHRLLRKQLRLRLSGFPAVSRENPVAGDSCEAVVLCLATELARSGTDCSELAQGLGAWSCSSNLCPSEHTVEINARNPSDDAWMSTGLYLPNGQLTEVCLCEAAACAGLKLQIGCHTDNLMSASKLSRAPVVTHQCHMDRTEQLVSNLWGGLLYVIVPTGCNLGPMSITIKRAVPAPYYKLGETSLEAWRSCIQESPAPWGELATDNIILTVPTADLRALEDPEPLLRLWDEMMEAIARLAAQPFPFRRPERIVADVQISAGWMHSGYPIMCHLESVSELIDETGMRSRGLWGPVHELGHNQQREQWEFPPHTTEATCNLWSVYVHETVLGIPRAQAHPALSPPERENRIKTHLEKGAPLCDWKVWTALETYLQLQEAFGWEPFTQLFAEYQTLSDIPNDNPGKMNLW", "length": 868, "header": "tr|A0A3Q1M013-1|F1N3Y1_BOVIN Computationally mapped isoform of TRPM8 channel associated factor 2 OS=Bos taurus OX=9913 GN=TCAF2 PE=3 SV=2 CANONICAL=F1N3Y1-1" }, "locus": { "chromosome": "4", "start_pos": 106998335, "end_pos": 106985574, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000078374.2", "url": "https://www.ensembl.org/id/ENSBTAT00000078374.2" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000061330.2", "url": "https://www.ensembl.org/id/ENSBTAP00000061330.2" } ] } }, { "isoform_ac": "F1N3Y1-1", "url": "https://www.uniprot.org/uniprotkb/F1N3Y1/entry", "sequence": { "sequence": "MATTPAAAFEALMDGVTSWELPEGPVPSELLLTGEAAFPVMVNDKGQVLIAASFYGRGRLVVVSHEGYLLDAGLARFLLNAVRWLSPSPGAPVGVHPSLASLAHILEGSGVEAQVHPEPAEPLGVYCISAYNDTMTAELIQFVKRGGGLLIGGQAWHWASQHGSDQVLSEFPGNQVTSVAGVYFTDTYGVKGRFKVSKKVPKIPLQVRCGEDLRQDQQQLLEGISELDIGTKGLPSQLLVHGALAFPLGLDASLRCFLAAARYGRGRVVLAAHEGMLSAPSLGPFLLNAVRWLAKGQTGKVGVNTSLEKLHTLLLEHGLECSLEPHLTSGVCVYCCTAYSDKEAKQLQEFVAEGGGLLIGGHAWWWASQNPGRSALADFPGNVILNSFGLSILPWTLDPGCFPVPSADSLNYHFRKALSEFQATLNLEGGNLEKNWLAKLRVDGAAFLQIPAEGVPAYASLHRLLRKQLRLRLSGFPAVSRENPVAGDSCEAVVLCLATELARSGTDCSELAQGLGAWSCSSNLCPSEHTVEINARNPSDDAWMSTGLYLPNGQLTEVCLCEAAACAGLKLQIGCHTDNLMSASKLSRAPVVTHQCHMDRTEQLVSNLWGGLLYVIVPTGCNLGPMSITIKRAVPAPYYKLGETSLEAWRSCIQESPAPWGELATDNIILTVPTADLRALEDPEPLLRLWDEMMEAIARLAAQPFPFRRPERIVADVQISAGWMHSGYPIMCHLESVSELIDETGMRSRGLWGPVHELGHNQQREQWEFPPHTTEATCNLWSVYVHETVLGIPRAQAHPALSPPERENRIKTHLEKGAPLCDWKVWTALETYLQLQEAFGWEPFTQLFAEYQTLSDIPNDNPGKMNLWVRKFSEKVQKNLAPFFEAWGWPVEKEVASSLACLPEWEENPMRMYI", "length": 914, "header": "tr|F1N3Y1-1|F1N3Y1_BOVIN Isoform 1 of TRPM8 channel associated factor 2 OS=Bos taurus OX=9913 GN=TCAF2 PE=3 SV=2 CANONICAL=F1N3Y1-1" }, "locus": { "chromosome": "4", "start_pos": 106998335, "end_pos": 106985436, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000007200.6", "url": "https://www.ensembl.org/id/ENSBTAT00000007200.6" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000007200.4", "url": "https://www.ensembl.org/id/ENSBTAP00000007200.4" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [], "orthologs": [ { "uniprot_canonical_ac": "A0A287ABA9-1", "protein_name": "Peptidase M60 domain-containing protein", "gene_name": "LOC110257570", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MAMTPAAAFEALMDGVTSWDVPKGPIPSELLLIGEAAFPVMVNDRGQVLIAASSYGQGRLVVVSHEGYLLDAGLAPFLLNAVRWLCPSPGAHVGVHPSLASLSNILQGSGVEAQIRPELREPLGVYCISAYSDAMAAELVQFVKRGGGLLIGGQAWYWASQHGRDKVLSKFPGNQVTSVAGVYFTDTCGDRSRFKVSKKVPKIPLQVSCGEALGQDQQQLLEGISELDVRTGGIPSQLLVHGPLAFPLGLDASLGCFLAAARYGRGRVVLAAHEGMLCAPKLGPFLLNAVHWLARGQTGKIGVNTRLKNLCAQLSECGLECSLEPHLTGDLCVYCCAAYSDTEATQLREFVAEGGGLLIGGQAWWWTSQNPGHSPLAGFPGNVILNCFGLSILARTLDPGCFPVPTPEKRSYHFRKALSEFQATLNHRGGNLEKSWLAKLRADGAAFLQIPAEGVPAYASLHRLLRKMLRLSGLPAVSRENPVASDSCEAAVLCLATELARSGTDCSQLVQGHGTGSCSSNPHPPEHPITVEIDGSNPGGDDSWVSTGLYLQNGQSAEISLSEAATSAGLKVQIGCHTDDLTGASTLSRAPVVTHQCLMDRTKRSVSCLWGGLLYVIVPKGSKLGPVSVTVQRAVPAPCYTLGKTSLDEWRSCIQESLAPWGELATDSVILTVPTAALRALEDPEPVLRLWDEMMRAIARLAAQPFPFRRPERIVADVQISAGWMHSGYPIMCHLESVQELISESGMRSRGLWGPIHELGHNQQRHGWEFPPHTTEATCNLWSVYVHETVLGIPRAQAHPALSPLEREKRIRTHLGKGAPLRDWTVWTALETYLQLQEAFGWEPFTQLFAEYQTLSDLPKDNTGKMNLWVKKFSEKVGKNLAPFFEAWGWPVQEDVAARLACLPAWQENPVKSYTPCRKE", "length": 920 }, "evidence": [ { "id": "F1N3Y1", "url": "https://omabrowser.org/oma/group/F1N3Y1/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "A6NFQ2-1", "protein_name": "TRPM8 channel-associated factor 2", "gene_name": "TCAF2", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MATIAAAAFEALMDGVTCWDVPRGPIPSELLLIGEAAFPVMVNDKGQVLIAASSYGRGRLVVVSHEGYLSHTGLAPFLLNAVSWLCPCPGAPVGVHPSLAPLVNILQDAGLEAQVKPEPGEPLGVYCINAYNDTLTATLIQFVKHGGGLLIGGQAWYWASQHGPDKVLSRFPGNKVTSVAGVYFTDTYGDRDRFKVSKKVPKIPLHVRYGEDVRQDQQQLLEGISELDIRTGGVPSQLLVHGALAFPLGLDASLNCFLAAAHYGRGRVVLAAHECLLCAPKMGPFLLNAVRWLARGQTGKVGVNTNLKDLCPLLSEHGLQCSLEPHLNSDLCVYCCKAYSDKEAKQLQEFVAEGGGLLIGGQAWWWASQNPGHCPLAGFPGNIILNCFGLSILPQTLKAGCFPVPTPEMRSYHFRKALSQFQAILNHENGNLEKSCLAKLRVDGAAFLQIPAEGVPAYISLHRLLRKMLRGSGLPAVSRENPVASDSYEAAVLSLATGLAHSGTDCSQLAQGLGTWTCSSSLYPSKHPITVEINGINPGNNDCWVSTGLYLLEGQNAEVSLSEAAASAGLRVQIGCHTDDLTKARKLSRAPVVTHQCWMDRTERSVSCLWGGLLYVIVPKGSQLGPVPVTIRGAVPAPYYKLGKTSLEEWKRQMQENLAPWGELATDNIILTVPTTNLQALKDPEPVLRLWDEMMQAVARLAAEPFPFRRPERIVADVQISAGWMHSGYPIMCHLESVKEIINEMDMRSRGVWGPIHELGHNQQRHGWEFPPHTTEATCNLWSVYVHETVLGIPRAQAHEALSPPERERRIKAHLGKGAPLCDWNVWTALETYLQLQEAFGWEPFTQLFAEYQTLSHLPKDNTGRMNLWVKKFSEKVKKNLVPFFEAWGWPIQKEVADSLASLPEWQENPMQVYLRARK", "length": 919 }, "evidence": [ { "id": "F1N3Y1", "url": "https://omabrowser.org/oma/group/F1N3Y1/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "M0RBL7-1", "protein_name": "TRPM8 channel associated factor 2C", "gene_name": "Tcaf2c", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MATTPDAAFEALMNGVTSWDLPKEFTPSELLLIGEAAFPVMVNDKGQVLIAASFYGQGRLVVLSHEGYLLHAGLAPFLLNAVSWLCPSPEAPIAVHSSLASLVNILRDSGVNALVQPEPGEALGVFCIDAYNDTLTEKLVQFVKHGGGLLIGGQACNWASQQGSDKVLFSFPGNQVTSVAGVYFTDVYGGINRFKVSKKVPKIPLHIRCWEELRRDQEQLLDGISMLDIRTGGVPSQLLVHGSLAFPVGLDNSFLSCFLAAARYGCGRVVLAAHEAMLCAPKMEPFLLNAIRWLSRDQGKTIGVNKSLKNLNSLLLKHGVKCSLESHLTSDMGVYCCVAYSDQDAKKIQEFVAEGGGLLIGGQSWWWASQNQGSSALRSFPGNVVLNPFGLSILPQTISPGCFPVLPIDIRNYHFRRALSEFQAMVNHKGGNLEKKYFGKLGVDGAGFLQIPAKGVPAYISVHRILRKMLRQAGLPAVSKNNPVSSQSCEAALLCLATELAHSGTDCSQIAHNHGTQTCSSDLCSSEHPITVEINGTNTGDSDVWMSTGLYLLEGQSTEISLSEPAASAGLKVQIGCHTDNLSHARQLFRAPVVTYQCCMDRTQRSVSCLWGGLLYIIVPKGCQLGPVSVTITKAVPAPYYKLGKTSLEEWKSCMQKNLGPWGELATDSVILTVPTESLKNLEDPAPLLQLWDEIMKAVAKLAAQPFPFERPERIVTDVQISNGWMHSGYPIMCHVESVQELVSLADIRSKGLWGPIHELGHNQQRSGWEFRPHTTEATCNLWSVYVHETVLGIPRAQAHPQLKPEEREKRIKEHLQKGAPLSDWKVWTALETYLQLQEVFGWEPFMNLFAEYQCIVHIPKDNESKMNLWLKLFSEKVQKNLVPFFEAWGWPIQKPVAEALACFPSWQDHPLKMYIGME", "length": 919 }, "evidence": [ { "id": "F1N3Y1", "url": "https://omabrowser.org/oma/group/F1N3Y1/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "Q921K8-1", "protein_name": "TRPM8 channel-associated factor 2", "gene_name": "Tcaf2", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MATTPDAAFEALMNGVTSWDLPKEFTPSELLLIGEAAFPVMVNDKGQVLIAVSFYGQGRLVVVSHESYLMHAGLAPFLLNAVSWLCPSPGTPIEVHSSLASLVNILRGSGINALVQPEPGEALGVYCIDAYNDTLTKKLVQFVKRGGGLLIGGQAWNWASQHGSDKVLFSFPGNKVTSVAGVYFTDVYGDINRFKVSKKIPKIPLYIRCWEELRHDQDQLLDGISMLDVRTGGVPSQLLVHGSLAFPLGLDNSFLSCFLAAAHYGRGRVVLAAHEAMLCAPKMEPFLLNAIRWLSRGQEDNIGVNTRLKNLNSLLLKHGLKCSLESHLTDDMCVYCCAAYSDQEAKKIQEFVAEGGGLLIGGQSWWWASQNPGSSALGSFPGNVILNTFGLSILPRTVSPGCFPILHIDIRNYHFRGALSEFQAMLNHKEGNLEKRYSGKLGVDGAGFLQIPAQGVPAYLSVHRILRKILRQAGLPAVSKSNPVSSHSYEAAILQLATELAHSGSDCSQIAHNLSSQTCSSNLSSSEHPITVEINGTNPGDRDVWMSTGLYLLEGQSTEISVSEPAASAGLKVQIGCHTDDLTFAIKLFRAPVVTYQCCMNRTQRSVSCLWGGLLYIIVPKGCQLGPVSVTITNAVPAPYYKLGKTSLEEWKSCIQKNLGPWGELATDNVILTVPTASLKTLENPEPLLQLWDEMMQAVARLASQPFPFQRPERIVADVQLSAGWMHSGYPIMCHMESVQELVSLANIRSKGLWGPIHELGHNQQCRGWEFPPHTTEATCNLWSVYVHETVLGIPRAQAHPQLKPEEREKRIKEHLQKGAPLQNWNVWTALETYLQLQEVFGWEPFITLFAEYQTIFYIPEDNECKMNIWLKLFSEKVQKNLVPFFEAWGWPIQKDVAEDLACYPSWEDHPLRMYMGSE", "length": 919 }, "evidence": [ { "id": "F1N3Y1", "url": "https://omabrowser.org/oma/group/F1N3Y1/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" } ], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 1, "go_terms": [ { "name": "plasma membrane", "id": "GO:0005886", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005886", "evidence": [ { "database": "UniProtKB", "id": "F1N3Y1", "url": "https://www.uniprot.org/uniprotkb/F1N3Y1" } ], "pmid": "" } ] }, { "name": "Molecular Function", "total": 1, "go_terms": [ { "name": "transmembrane transporter binding", "id": "GO:0044325", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0044325", "evidence": [ { "database": "UniProtKB", "id": "F1N3Y1", "url": "https://www.uniprot.org/uniprotkb/F1N3Y1" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 2, "go_terms": [ { "name": "positive regulation of protein targeting to membrane", "id": "GO:0090314", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0090314", "evidence": [ { "database": "UniProtKB", "id": "F1N3Y1", "url": "https://www.uniprot.org/uniprotkb/F1N3Y1" } ], "pmid": "" }, { "name": "negative regulation of anion channel activity", "id": "GO:0010360", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0010360", "evidence": [ { "database": "UniProtKB", "id": "F1N3Y1", "url": "https://www.uniprot.org/uniprotkb/F1N3Y1" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 132, "end_pos": 134, "annotation": "n_glycosylation_sequon" }, { "start_pos": 304, "end_pos": 306, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [ { "pdb_id": "AF-F1N3Y1-F1", "pdb_chain": "global", "start_pos": 1, "end_pos": 914, "overlap": "1.0", "method": "AlphaFold", "type": "alphafold", "resolution": -1.0, "url": "https://data.glygen.org/ln2downloads/pdb/current/AF-F1N3Y1-F1.pdb", "url_external": "https://alphafold.ebi.ac.uk/entry/F1N3Y1" } ], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "F1N3Y1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1N3Y1" }, { "id": "PS51723", "database": "PROSITE", "url": "https://prosite.expasy.org/PS51723" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "Peptidase M60", "eco_id": "ECO_0000259", "start_pos": 541, "end_pos": 840, "start_aa": "Asp", "end_aa": "Gly", "glycosite_overlap": [] } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" }, { "name": "homologset.oma", "label": "OMA Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 132, "end_pos": 134 }, { "start_pos": 304, "end_pos": 306 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { 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"yes" } }, { "uniprot_canonical_ac": "F6Q9M2-1", "uniprot_ac": "F6Q9M2", "uniprot_id": "F6Q9M2_BOVIN", "mass": { "chemical_mass": 53514.0, "monoisotopic_mass": 53514.0 }, "refseq": {}, "gene_names": [ { "name": "GRAMD2B", "type": "recommended", "evidence": [ { "id": "F6Q9M2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F6Q9M2" } ] } ], "protein_names": [ { "name": "GRAM domain containing 2B", "type": "synonym", "evidence": [ { "id": "F6Q9M2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F6Q9M2/entry#names_and_taxonomy" } ] } ], "function": [], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Bos taurus", "taxid": 9913, "evidence": [ { "database": "UniProtKB", "id": "F6Q9M2", "url": "https://www.uniprot.org/uniprotkb/F6Q9M2" } ], "common_name": "Bovine", "glygen_name": "Bovine", "reference_species": "Bos taurus [9913]" } ], "gene": [ { "name": "GRAMD2B", "url": "https://www.uniprot.org/uniprotkb/F6Q9M2", "locus": { "chromosome": "7", "start_pos": 27346924, "end_pos": 27494197, "strand": "+", "evidence": [ { "database": "Ensembl Gene", "id": "ENSBTAG00000014974", "url": "https://www.ensembl.org/id/ENSBTAG00000014974" } ] } } ], "crossref": [ { "id": "F6Q9M2", "url": "https://alphafold.ebi.ac.uk/entry/F6Q9M2", "database": "AlphaFoldDB", "categories": [] }, { "id": "ENSBTAG00000014974", "url": "https://bgee.org/?page=gene&gene_id=ENSBTAG00000014974", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "cd13220", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd13220", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "IPR004182", "url": "https://www.ebi.ac.uk/interpro/entry/IPR004182", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR011993", "url": "https://www.ebi.ac.uk/interpro/entry/IPR011993", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR052633", "url": "https://www.ebi.ac.uk/interpro/entry/IPR052633", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "A0A3Q1LPH6", "url": "https://www.orthodb.org/?gene=A0A3Q1LPH6", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A3Q1MC13", "url": "https://www.orthodb.org/?gene=A0A3Q1MC13", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "F6Q9M2", "url": "https://www.orthodb.org/?gene=F6Q9M2", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR46645", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR46645", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR46645:SF2", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR46645:SF2", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF02893", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF02893", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "A0A3Q1LPH6", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1LPH6", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A3Q1LPH6-1", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1LPH6-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A3Q1MC13", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1MC13", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A3Q1MC13-1", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1MC13-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A3Q1MRL7", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1MRL7", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A3Q1MRL7-1", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1MRL7-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0AAA9SC01", "url": "https://www.uniprot.org/uniprotkb/A0AAA9SC01", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0AAA9SC01-1", "url": "https://www.uniprot.org/uniprotkb/A0AAA9SC01-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0AAA9SJB7", "url": "https://www.uniprot.org/uniprotkb/A0AAA9SJB7", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0AAA9SJB7-1", "url": "https://www.uniprot.org/uniprotkb/A0AAA9SJB7-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0AAA9TVV7", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TVV7", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0AAA9TVV7-1", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TVV7-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "F6Q9M2", "url": "https://www.uniprot.org/uniprotkb/F6Q9M2", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "F6Q9M2-1", "url": "https://www.uniprot.org/uniprotkb/F6Q9M2-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MVKKRLSSGNDTMFRSEIPGSPGKSGAEAQNSIPDSPGSVFLSSEAENGVEEKKKVCRSPGALSPTPSSEAESQDQKRTISLRSKSSFDGAPVANEKSDCKTESKNDSKIERKKSSSSSQDKANMHFHKLFLDVPTEEPLRQSFTCALQKEILYQGKLFVSENWICFHSKVFGKDTKISIPAFSVTLIKKTKTALLVPNALIIATVTDRYIFVSLLSRDSTYKLLKSVCGHLENTGIGSGPSPSSLENSFRADRPSSLPLDFNDEFSDLDGVVRRRRQDMEGYSSSGSQTPESENSRDFHVTESQTVLNVSKGEAKPTRADPLVNRVPEGKAKSLPGHGKERIMMPGQSETTGIIPRVKSEKCPTLHHILIFYAIVVCALIISTFYMRYRINTLEEQLGSLTSIVDTHQTESEVTSLSFARLFATLWTIVYKAPLSMEFSRQTAPSGLGSQVQLNVEALCQELTANIMRLEKIQNNLQKLLENGD", "length": 485, "header": "tr|F6Q9M2-1|F6Q9M2_BOVIN Isoform 1 of GRAM domain containing 2B OS=Bos taurus OX=9913 GN=GRAMD2B PE=4 SV=2 CANONICAL=F6Q9M2-1" }, "isoforms": [ { "isoform_ac": "A0A3Q1LPH6-1", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1LPH6/entry", "sequence": { "sequence": "MWTTQSLPKCSGRGRAKLAQPTQRLRMVWRRKRRYAGRQERCLPPHPARPSPRTRREPFPCAHVFSANLFLTQDQASKSSFDGAPVANEKSDCKTESKNDSKIERKKSSSSSQDKANMHFHKLFLDVPTEEPLRQSFTCALQKEILYQGKLFVSENWICFHSKVFGKDTKISIPAFSVTLIKKTKTALLVPNALIIATVTDRYIFVSLLSRDSTYKLLKSVCGHLENTGIGSGPSPSSLENSFRADRPSSLPLDFNDEFSDLDGVVRRRRQDMEGYSSSGSQTPESENSRDFHVTESQTVLNVSKGEAKPTRADPLVNRVPEGKAKSLPGHGQSETTGIIPRVKSEKCPTLHHILIFYAIVVCALIISTFYMRYRINTLEEQLGSLTSIVDTHQTEQTAPSGLGSQVQLNVEALCQELTANIMRLEKIQNNLQKLLENGD", "length": 440, "header": "tr|A0A3Q1LPH6-1|F6Q9M2_BOVIN Computationally mapped isoform of GRAM domain containing 2B OS=Bos taurus OX=9913 GN=GRAMD2B PE=4 SV=2 CANONICAL=F6Q9M2-1" }, "locus": { "chromosome": "7", "start_pos": 27434634, "end_pos": 27359225, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000084296.2", "url": "https://www.ensembl.org/id/ENSBTAT00000084296.2" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000058909.2", "url": "https://www.ensembl.org/id/ENSBTAP00000058909.2" } ] } }, { "isoform_ac": "A0A3Q1MC13-1", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1MC13/entry", "sequence": { "sequence": "MTELQQDVDDTKSAKVLGKRESKVGSAHSEAENGVEEKKKVCRSPGALSPTPSSEAESQDQKRTISLRSKSSFDGAPVANEKSDCKTESKNDSKIERKKSSSSSQDKANMHFHKLFLDVPTEEPLRQSFTCALQKEILYQGKLFVSENWICFHSKVFGKDTKISIPAFSVTLIKKTKTALLVPNALIIATVTDRYIFVSLLSRDSTYKLLKSVCGHLENTGIGSGPSPSSLENSFRADRPSSLPLDFNDEFSDLDGVVRRRRQDMEGYSSSGSQTPESENSRDFHVTESQTVLNVSKGEAKPTRADPLVNRVPEGKAKSLPGHGKERIMMPGQSETTGIIPRVKSEKCPTLHHILIFYAIVLTQFEAVAHNRGGCAQFGFQIKQGICESQDLKTQTLPGQDFRQYLAGGGAPA", "length": 413, "header": "tr|A0A3Q1MC13-1|F6Q9M2_BOVIN Computationally mapped isoform of GRAM domain containing 2B OS=Bos taurus OX=9913 GN=GRAMD2B PE=4 SV=1 CANONICAL=F6Q9M2-1" }, "locus": { "chromosome": "7", "start_pos": 27434653, "end_pos": 27368539, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000067925.2", "url": "https://www.ensembl.org/id/ENSBTAT00000067925.2" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000071632.1", "url": "https://www.ensembl.org/id/ENSBTAP00000071632.1" } ] } }, { "isoform_ac": "A0A3Q1MRL7-1", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1MRL7/entry", "sequence": { "sequence": "VWKIQQALAAKRQTLQAQLMPWKSRLQGKAAKPKDPDLELSEAENGVEEKKKVCRSPGALSPTPSSEAESQDQKRTISLRSKSSFDGAPVANEKSDCKTESKNDSKIERKKSSSSSQDKANMHFHKLFLDVPTEEPLRQSFTCALQKEILYQGKLFVSENWICFHSKVFGKDTKISIPAFSVTLIKKTKTALLVPNALIIATVTDRYIFVSLLSRDSTYKLLKSVCGHLENTGIGSGPSPSSLENSFRADRPSSLPLDFNDEFSDLDGVVRRRRQDMEGYSSSGSQTPESENSRDFHVTESQTVLNVSKGEAKPTRADPLVNRVPEGKAKSLPGHGQSETTGIIPRVKSEKCPTLHHILIFYAIVVCALIISTFYMRYRINTLEEQLGSLTSIVDTHQTEQTAPSGLGSQVQLNVEALCQELTANIMRLEKIQNNLQKLLENGD", "length": 444, "header": "tr|A0A3Q1MRL7-1|F6Q9M2_BOVIN Computationally mapped isoform of GRAM domain containing 2B OS=Bos taurus OX=9913 GN=GRAMD2B PE=4 SV=1 CANONICAL=F6Q9M2-1" }, "locus": { "chromosome": "7", "start_pos": 27494197, "end_pos": 27359225, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000067656.2", "url": "https://www.ensembl.org/id/ENSBTAT00000067656.2" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000074459.2", "url": "https://www.ensembl.org/id/ENSBTAP00000074459.2" } ] } }, { "isoform_ac": "A0AAA9SC01-1", "url": "https://www.uniprot.org/uniprotkb/A0AAA9SC01/entry", "sequence": { "sequence": "MTELQQDVDDTKSAKVLGKRESKVGSAHSEAENGVEEKKKVCRSPGALSPTPSSEAESQDQKRTISLRSKSSFDGAPVANEKSDCKTESKNDSKIERKKSSSSSQDKANMHFHKLFLDVPTEEPLRQSFTCALQKEILYQGKLFVSENWICFHSKVFGKDTKISIPAFSVTLIKKTKTALLVPNALIIATVTDRYIFVSLLSRDSTYKLLKSVCGHLENTGIGSGPSPSSLENSFRADRPSSLPLDFNDEFSDLDGVVRRRRQDMEGYSSSGSQTPESENSRDFHVTESQTVLNVSKGEAKPTRADPLVNRVPEGKAKSLPGHGKERIMMPGQSETTGIIPRVKSEKCPTLHHILIFYAIVVCALIISTFYMRYRINTLEEQLGSLTSIVDTHQTEYKTTYKSCLRMVTEARATQYLVLPFK", "length": 422, "header": "tr|A0AAA9SC01-1|F6Q9M2_BOVIN Computationally mapped isoform of GRAM domain containing 2B OS=Bos taurus OX=9913 GN=GRAMD2B PE=4 SV=1 CANONICAL=F6Q9M2-1" }, "locus": { "chromosome": "7", "start_pos": 27434653, "end_pos": 27359185, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000088059.1", "url": "https://www.ensembl.org/id/ENSBTAT00000088059.1" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000079761.1", "url": "https://www.ensembl.org/id/ENSBTAP00000079761.1" } ] } }, { "isoform_ac": "A0AAA9SJB7-1", "url": "https://www.uniprot.org/uniprotkb/A0AAA9SJB7/entry", "sequence": { "sequence": "MTELQQDVDDTKSAKVLGKRESKVGSAHSEAENGVEEKKKVCRSPGALSPTPSSEAESQDQKRTISLRSKSSFDGAPVANEKSDCKTESKNDSKIERKKSSSSSQDKANMHFHKLFLDVPTEEPLRQSFTCALQKEILYQGKLFVSENWICFHSKVFGKDTKISIPAFSVTLIKKTKTALLVPNALIIATVTDRYIFVSLLSRDSTYKLLKSVCGHLENTGIGSGPSPSSLENSFRADRPSSLPLDFNDEFSDLDGVVRRRRQDMEGYSSSGSQTPESENSRDFHVTESQTVLNVSKGEAKPTRADPLVNRVPEGKAKSLPGHGKERIMMPGQSETTGIIPRVKSEKCPTLHHILIFYAIVVCALIISTFYMRYRINTLEEQLGSLTSIVDTHQTEQTAPSGLGSQVQLNVEALCQELTANIMRLEKDATPLHAKEGSLILTRK", "length": 444, "header": "tr|A0AAA9SJB7-1|F6Q9M2_BOVIN Computationally mapped isoform of GRAM domain containing 2B OS=Bos taurus OX=9913 GN=GRAMD2B PE=4 SV=1 CANONICAL=F6Q9M2-1" }, "locus": { "chromosome": "7", "start_pos": 27434653, "end_pos": 27347780, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000095743.1", "url": "https://www.ensembl.org/id/ENSBTAT00000095743.1" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000085428.1", "url": "https://www.ensembl.org/id/ENSBTAP00000085428.1" } ] } }, { "isoform_ac": "A0AAA9TVV7-1", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TVV7/entry", "sequence": { "sequence": "ADKANMHFHKLFLDVPTEEPLRQSFTCALQKEILYQGKLFVSENWICFHSKVFGKDTKISIPAFSVTLIKKTKTALLVPNALIIATVTDRYIFVSLLSRDSTYKLLKSVCGHLENTGIGSGPSPSSLENSFRADRPSSLPLDFNDEFSDLDGVVRRRRQDMEGYSSSGSQTPESENSRDFHVTESQTVLNVSKGEAKPTRADPLVNRVPEGKAKSLPGHGQSETTGIIPRVKSEKCPTLHHILIFYAIVVCALIISTFYMRYRINTLEEQLGSLTSIVDTHQTEQTAPSGLGSQVQLNVEALCQELTANIMRLEKIQNNLQKLLENGD", "length": 328, "header": "tr|A0AAA9TVV7-1|F6Q9M2_BOVIN Computationally mapped isoform of GRAM domain containing 2B OS=Bos taurus OX=9913 GN=GRAMD2B PE=4 SV=1 CANONICAL=F6Q9M2-1" }, "locus": { "chromosome": "7", "start_pos": 27387778, "end_pos": 27359225, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000098412.1", "url": "https://www.ensembl.org/id/ENSBTAT00000098412.1" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000101300.1", "url": "https://www.ensembl.org/id/ENSBTAP00000101300.1" } ] } }, { "isoform_ac": "F6Q9M2-1", "url": "https://www.uniprot.org/uniprotkb/F6Q9M2/entry", "sequence": { "sequence": "MVKKRLSSGNDTMFRSEIPGSPGKSGAEAQNSIPDSPGSVFLSSEAENGVEEKKKVCRSPGALSPTPSSEAESQDQKRTISLRSKSSFDGAPVANEKSDCKTESKNDSKIERKKSSSSSQDKANMHFHKLFLDVPTEEPLRQSFTCALQKEILYQGKLFVSENWICFHSKVFGKDTKISIPAFSVTLIKKTKTALLVPNALIIATVTDRYIFVSLLSRDSTYKLLKSVCGHLENTGIGSGPSPSSLENSFRADRPSSLPLDFNDEFSDLDGVVRRRRQDMEGYSSSGSQTPESENSRDFHVTESQTVLNVSKGEAKPTRADPLVNRVPEGKAKSLPGHGKERIMMPGQSETTGIIPRVKSEKCPTLHHILIFYAIVVCALIISTFYMRYRINTLEEQLGSLTSIVDTHQTESEVTSLSFARLFATLWTIVYKAPLSMEFSRQTAPSGLGSQVQLNVEALCQELTANIMRLEKIQNNLQKLLENGD", "length": 485, "header": "tr|F6Q9M2-1|F6Q9M2_BOVIN Isoform 1 of GRAM domain containing 2B OS=Bos taurus OX=9913 GN=GRAMD2B PE=4 SV=2 CANONICAL=F6Q9M2-1" }, "locus": { "chromosome": "7", "start_pos": 27477345, "end_pos": 27359225, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000019934.7", "url": "https://www.ensembl.org/id/ENSBTAT00000019934.7" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000019934.7", "url": "https://www.ensembl.org/id/ENSBTAP00000019934.7" } ] } } ], "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "other", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 66, "start_aa": "Thr", "end_pos": 66, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr66", "evidence": [ { "id": "", "database": "GlyGen", "url": "https://data.glygen.org/" } ], "filter_code": "000000000000000010000.00000000001000.0.01000" } ], "phosphorylation": [], "glycation": [], "keywords": [ "glycoprotein", "glycoprotein_predicted" ], "publication": [], "pathway": [], "orthologs": [], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 2, "go_terms": [ { "name": "cytoplasm", "id": "GO:0005737", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005737", "evidence": [ { "database": "UniProtKB", "id": "F6Q9M2", "url": "https://www.uniprot.org/uniprotkb/F6Q9M2" } ], "pmid": "" }, { "name": "cytoplasmic microtubule", "id": "GO:0005881", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005881", "evidence": [ { "database": "UniProtKB", "id": "F6Q9M2", "url": "https://www.uniprot.org/uniprotkb/F6Q9M2" } ], "pmid": "" } ] }, { "name": "Molecular Function", "total": 1, "go_terms": [ { "name": "identical protein binding", "id": "GO:0042802", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0042802", "evidence": [ { "database": "UniProtKB", "id": "F6Q9M2", "url": "https://www.uniprot.org/uniprotkb/F6Q9M2" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 106, "end_pos": 108, "annotation": "n_glycosylation_sequon" }, { "start_pos": 10, "end_pos": 12, "annotation": "n_glycosylation_sequon" }, { "start_pos": 309, "end_pos": 311, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [ { "pdb_id": "AF-F6Q9M2-F1", "pdb_chain": "global", "start_pos": 1, "end_pos": 485, "overlap": "1.0", "method": "AlphaFold", "type": "alphafold", "resolution": -1.0, "url": "https://data.glygen.org/ln2downloads/pdb/current/AF-F6Q9M2-F1.pdb", "url_external": "https://alphafold.ebi.ac.uk/entry/F6Q9M2" } ], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "F6Q9M2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F6Q9M2" }, { "id": "SM00568", "database": "SMART", "url": "http://smart.embl.de/smart/do_annotation.pl?DOMAIN=SM00568" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "GRAM", "eco_id": "ECO_0000259", "start_pos": 125, "end_pos": 192, "start_aa": "Met", "end_aa": "Lys", "glycosite_overlap": [] } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [ 66 ], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 106, "end_pos": 108 }, { "start_pos": 10, "end_pos": 12 }, { "start_pos": 309, "end_pos": 311 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 1 }, { "field": "total_sites", "count": 1 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 1 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "exact_sites", "count": 1 }, { "field": "exact_o_linked_sites", "count": 1 }, { "field": "fuzzy_sites", "count": 0 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_pos", "start_aa", "end_pos", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 1 }, { "field": "total_sites", "count": 1 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 1 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "exact_sites", "count": 1 }, { "field": "exact_o_linked_sites", "count": 1 }, { "field": "fuzzy_sites", "count": 0 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_pos", "start_aa", "end_pos", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": 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"MNPVYSPVQPGAPYGNPKNMAYTGYPTAYPAAAPAYNPSLYPTNSPSYAPEFQFLHSAYATLLMKQAWPQNSSSCGTEGTFHLPVDTGTENRTYQASSAAFRYTAGTPYKVPPTQSNTAPPPYSPSPNPYQTAMYPIRSAYPQQNLYAQGAYYTQPVYAAQPHVIHHTTVVQPNSIPSAIYPAPVAAPRTNGVAMGMVAGTTMAMSAGTLLTAPQHTAIGAHPVSMPTYRAQGTPAYSYVPPHW", "length": 244, "header": "tr|F1N396-1|F1N396_BOVIN Isoform 1 of Family with sequence similarity 168 member A OS=Bos taurus OX=9913 GN=FAM168A PE=3 SV=2 CANONICAL=F1N396-1" }, "isoforms": [ { "isoform_ac": "A0A3Q1LQJ4-1", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1LQJ4/entry", "sequence": { "sequence": "MDCSTPGFPVHHQLPELAETHVHQDSQLSTMNPVYSPVQPGAPYGNPKNMAYTGYPTAYPAAAPAYNPSLYPTNSPSYAPATLLMKQAWPQNSSSCGTEGTFHLPVDTGTENRTYQASSAAFRYTAGTPYKVPPTQSNTAPPPYSPSPNPYQTAMYPIRSAYPQQNLYAQGAYYTQPVYAAQPHVIHHTTVVQPNSIPSAIYPAPVAAPRTNGVAMGMVAGTTMAMSAGTLLTAPQHTAIGAHPVSMPTYRAQGTPAYSYVPPHW", "length": 265, "header": "tr|A0A3Q1LQJ4-1|F1N396_BOVIN Computationally mapped isoform of Family with sequence similarity 168 member A OS=Bos taurus OX=9913 GN=FAM168A PE=3 SV=2 CANONICAL=F1N396-1" }, "locus": { "chromosome": "15", "start_pos": 52982087, "end_pos": 52890072, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000086399.2", "url": "https://www.ensembl.org/id/ENSBTAT00000086399.2" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000059260.2", "url": "https://www.ensembl.org/id/ENSBTAP00000059260.2" } ] } }, { "isoform_ac": "A0A3Q1M0H1-1", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1M0H1/entry", "sequence": { "sequence": "MDCSTPGFPVHHQLPELAETHVHQDSQLSTMNPVYSPVQPGAPYGNPKNMAYTGYPTAYPAAAPAYNPSLYPTNSPSYAPEFQFLHSAYATLLMKQAWPQNSSSCGTEGTFHLPVDTGTENRTYQASSAAFRYTAGTPYKVPPTQSNTAPPPYSPSPNPYQTAMYPIRSAYPQQNLYAQGAYYTQPVYAAQPHVIHHTTVVQPNSIPSAIYPAPVAAPRTNGVAMGMVAGTTMAMSAGTLLTAPQHTAIGAHPVSMPTYRAQGTPAYSYVPPHW", "length": 274, "header": "tr|A0A3Q1M0H1-1|F1N396_BOVIN Computationally mapped isoform of Family with sequence similarity 168 member A OS=Bos taurus OX=9913 GN=FAM168A PE=3 SV=1 CANONICAL=F1N396-1" }, "locus": { "chromosome": "15", "start_pos": 52982087, "end_pos": 52890072, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000086304.2", "url": "https://www.ensembl.org/id/ENSBTAT00000086304.2" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000061475.2", "url": "https://www.ensembl.org/id/ENSBTAP00000061475.2" } ] } }, { "isoform_ac": "A0A3Q1NLF7-1", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1NLF7/entry", "sequence": { "sequence": "MADGQMEDSQLSTMNPVYSPVQPGAPYGNPKNMAYTGYPTAYPAAAPAYNPSLYPTNSPSYAPATLLMKQAWPQNSSSCGTEGTFHLPVDTGTENRTYQASSAAFRYTAGTPYKVPPTQSNTAPPPYSPSPNPYQTAMYPIRSAYPQQNLYAQGAYYTQPVYAAQPHVIHHTTVVQPNSIPSAIYPAPVAAPRTNGVAMGMVAGTTMAMSAGTLLTAPQHTAIGAHPVSMPTYRAQGTPAYSYVPPHW", "length": 248, "header": "tr|A0A3Q1NLF7-1|F1N396_BOVIN Computationally mapped isoform of Family with sequence similarity 168 member A OS=Bos taurus OX=9913 GN=FAM168A PE=3 SV=2 CANONICAL=F1N396-1" }, "locus": { "chromosome": "15", "start_pos": 53016515, "end_pos": 52890072, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000085684.2", "url": "https://www.ensembl.org/id/ENSBTAT00000085684.2" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000073237.2", "url": "https://www.ensembl.org/id/ENSBTAP00000073237.2" } ] } }, { "isoform_ac": "A0AAA9S060-1", "url": "https://www.uniprot.org/uniprotkb/A0AAA9S060/entry", "sequence": { "sequence": "MNPVYSPVQPGAPYGNPKNMAYTGYPTAYPAAAPAYNPSLYPTNSPSYAPATLLMKQAWPQNSSSCGTEGTFHLPVDTGTENRTYQASSAAFSTLLTAPQHTAIGAHPVSMPTYRAQGTPAYSYVPPHW", "length": 129, "header": "tr|A0AAA9S060-1|F1N396_BOVIN Computationally mapped isoform of Family with sequence similarity 168 member A OS=Bos taurus OX=9913 GN=FAM168A PE=3 SV=1 CANONICAL=F1N396-1" }, "locus": { "chromosome": "15", "start_pos": 52951383, "end_pos": 52890072, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000128100.1", "url": "https://www.ensembl.org/id/ENSBTAT00000128100.1" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000076715.1", "url": "https://www.ensembl.org/id/ENSBTAP00000076715.1" } ] } }, { "isoform_ac": "A0AAA9SPB4-1", "url": "https://www.uniprot.org/uniprotkb/A0AAA9SPB4/entry", "sequence": { "sequence": "MSDSVRPHRRQPVRLPCPWDSPGKNTGVGCHFLLQCMKVKSESEVTQSCPTLSDPMDCSLPGSSTHGIFQDSQLSTMNPVYSPVQPGAPYGNPKNMAYTGYPTAYPAAAPAYNPSLYPTNSPSYAPEFQFLHSAYATLLMKQAWPQNSSSCGTEGTFHLPVDTGTENRTYQASSAAFRYTAGTPYKVPPTQSNTAPPPYSPSPNPYQTAMYPIRSAYPQQNLYAQGAYYTQPVYAAQPHVIHHTTVVQPNSIPSAIYPAPVAAPRTNGVAMGMVAGTTMAMSAGTLLTAPQHTAIGAHPVSMPTYRAQGTPAYSYVPPHW", "length": 320, "header": "tr|A0AAA9SPB4-1|F1N396_BOVIN Computationally mapped isoform of Family with sequence similarity 168 member A OS=Bos taurus OX=9913 GN=FAM168A PE=3 SV=2 CANONICAL=F1N396-1" }, "locus": { "chromosome": "15", "start_pos": 53034159, "end_pos": 52890072, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000133345.2", "url": "https://www.ensembl.org/id/ENSBTAT00000133345.2" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000085761.2", "url": "https://www.ensembl.org/id/ENSBTAP00000085761.2" } ] } }, { "isoform_ac": "F1N396-1", "url": "https://www.uniprot.org/uniprotkb/F1N396/entry", "sequence": { "sequence": "MNPVYSPVQPGAPYGNPKNMAYTGYPTAYPAAAPAYNPSLYPTNSPSYAPEFQFLHSAYATLLMKQAWPQNSSSCGTEGTFHLPVDTGTENRTYQASSAAFRYTAGTPYKVPPTQSNTAPPPYSPSPNPYQTAMYPIRSAYPQQNLYAQGAYYTQPVYAAQPHVIHHTTVVQPNSIPSAIYPAPVAAPRTNGVAMGMVAGTTMAMSAGTLLTAPQHTAIGAHPVSMPTYRAQGTPAYSYVPPHW", "length": 244, "header": "tr|F1N396-1|F1N396_BOVIN Isoform 1 of Family with sequence similarity 168 member A OS=Bos taurus OX=9913 GN=FAM168A PE=3 SV=2 CANONICAL=F1N396-1" }, "locus": { "chromosome": "15", "start_pos": 52951383, "end_pos": 52890072, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000021930.5", "url": "https://www.ensembl.org/id/ENSBTAT00000021930.5" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000021930.4", "url": "https://www.ensembl.org/id/ENSBTAP00000021930.4" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [], "orthologs": [ { "uniprot_canonical_ac": "A0A8C2MMZ9-1", "protein_name": "Protein FAM168A isoform X1", "gene_name": "Fam168a", "tax_id": 10029, "organism": "Cricetulus griseus", "sequence": { "sequence": "MNPVYSPVQPGAPYGNPKNMAYTGYPTAYPAAAPAYNPSLYPTNSPSYAPEFQFLHSAYATLLMKQAWPQNSSSCGTEGTFHLPVDTGTENRTYQASSAAFRYTAGTPYKVPPTQSNTAPPPYSPSPNPYQTAMYPIRSAYPQQNLYAQGAYYTQPVYAAQPHVIHHTTVVQPNSIPSAIYPAPVAAPRTNGVAMGMVAGTTMAMSAGTLLTTPQHTAIGAHPVSMPTYRAQGTPAYSYVPPHW", "length": 244 }, "evidence": [ { "id": "F1N396", "url": "https://omabrowser.org/oma/group/F1N396/", "database": "OMA" } ], "glygen_name": "Hamster", "common_name": "Chinese hamster" }, { "uniprot_canonical_ac": "A0A8I6A572-1", "protein_name": "Family with sequence similarity 168, member A", "gene_name": "Fam168a", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MNPVYSPVQPGAPYGNPKNMAYTGYPTAYPAAAPAYNPSLYPTSSPSYAPEFQFLHSAYGISPLFPLSFPSGYHDATLLMKQAWPQNSSSCGTEGTFHLPVDTGTENRTYQASSAAFRYTAGTPYKVPPTQSNTAPPPYSPSPNPYQTAMYPIRSAYPQQNLYAQGAYYTQPVYAAQPHVIHHTTVVQPNSIPSAIYPAPVAAPRTNGVAMGMVAGTTMAMSAGTLLTTPQHTAIGAHPVSMPTYRAQGTPAYSYVPPHW", "length": 260 }, "evidence": [ { "id": "F1N396", "url": "https://omabrowser.org/oma/group/F1N396/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "A0A8W4F9R3-1", "protein_name": "Family with sequence similarity 168 member A", "gene_name": "FAM168A", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MNPVYSPVQPGAPYGNPKNMAYTGYPTAYPAAAPAYNPSLYPTSSPSYAPEFQFLHSAYATLLMKQAWPQNSSSCGTEGTFHLPVDTGTENRTYQASSAAFRYTAGTPYKVPPTQSNTAPPPYSPSPNPYQTAMYPIRSAYPQQNLYAQGAYYTQPVYAAQPHVIHHTTVVQPNSIPSAIYPAPVAAPRTNGVAMGMVAGTTMAMSAGTLLTAPQHTAIGAHPVSMPTYRAQGTPAYSYVPPHW", "length": 244 }, "evidence": [ { "id": "F1N396", "url": "https://omabrowser.org/oma/group/F1N396/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "Q8BGZ2-1", "protein_name": "Protein FAM168A", "gene_name": "Fam168a", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MNPVYSPVQPGAPYGNPKNMAYTGYPTAYPAAAPAYNPSLYPTNSPSYAPEFQFLHSAYATLLMKQAWPQNSSSCGTEGTFHLPVDTGTENRTYQASSAAFRYTAGTPYKVPPTQSNTAPPPYSPSPNPYQTAMYPIRSAYPQQNLYAQGAYYTQPVYAAQPHVIHHTTVVQPNSIPSAIYPAPVAAPRTNGVAMGMVAGTTMAMSAGTLLTTPQHTAIGAHPVSMPTYRAQGTPAYSYVPPHW", "length": 244 }, "evidence": [ { "id": "F1N396", "url": "https://omabrowser.org/oma/group/F1N396/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q92567-1", "protein_name": "Protein FAM168A", "gene_name": "FAM168A", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MNPVYSPVQPGAPYGNPKNMAYTGYPTAYPAAAPAYNPSLYPTNSPSYAPEFQFLHSAYATLLMKQAWPQNSSSCGTEGTFHLPVDTGTENRTYQASSAAFRYTAGTPYKVPPTQSNTAPPPYSPSPNPYQTAMYPIRSAYPQQNLYAQGAYYTQPVYAAQPHVIHHTTVVQPNSIPSAIYPAPVAAPRTNGVAMGMVAGTTMAMSAGTLLTTPQHTAIGAHPVSMPTYRAQGTPAYSYVPPHW", "length": 244 }, "evidence": [ { "id": "F1N396", "url": "https://omabrowser.org/oma/group/F1N396/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" } ], "go_annotation": { "categories": [ { "name": "Biological Process", "total": 1, "go_terms": [ { "name": "positive regulation of base-excision repair", "id": "GO:1905053", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:1905053", "evidence": [ { "database": "UniProtKB", "id": "F1N396", "url": "https://www.uniprot.org/uniprotkb/F1N396" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 71, "end_pos": 73, "annotation": "n_glycosylation_sequon" }, { "start_pos": 91, "end_pos": 93, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" }, { "name": "homologset.oma", "label": "OMA Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 71, "end_pos": 73 }, { "start_pos": 91, "end_pos": 93 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ], "tool_support": { "graph_view": "yes" } }, { "uniprot_canonical_ac": "F6PUM3-1", "uniprot_ac": "F6PUM3", "uniprot_id": "F6PUM3_BOVIN", "mass": { "chemical_mass": 65617.0, "monoisotopic_mass": 65617.0 }, "refseq": {}, "gene_names": [ { "name": "ZYX", "type": "recommended", "evidence": [ { "id": "F6PUM3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F6PUM3" } ] } ], "protein_names": [ { "name": "Zyxin", "type": "recommended", "evidence": [ { "id": "F6PUM3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F6PUM3/entry#names_and_taxonomy" } ] } ], "function": [ { "annotation": "Adhesion plaque protein. Binds alpha-actinin and the CRP protein. Important for targeting TES and ENA/VASP family members to focal adhesions and for the formation of actin-rich structures. May be a component of a signal transduction pathway that mediates adhesion-stimulated changes in gene expression.", "evidence": [ { "database": "UniProtKB", "id": "A0A3Q1LQJ9", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1LQJ9#function" }, { "database": "UniProtKB", "id": "ARBA00057245", "url": "https://www.uniprot.org/uniprotkb/ARBA00057245#function" }, { "database": "UniProtKB", "id": "F6PUM3", "url": "https://www.uniprot.org/uniprotkb/F6PUM3#function" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Bos taurus", "taxid": 9913, "evidence": [ { "database": "UniProtKB", "id": "F6PUM3", "url": "https://www.uniprot.org/uniprotkb/F6PUM3" } ], "common_name": "Bovine", "glygen_name": "Bovine", "reference_species": "Bos taurus [9913]" } ], "gene": [ { "name": "ZYX", "url": "https://www.uniprot.org/uniprotkb/F6PUM3", "locus": { "chromosome": "4", "start_pos": 106788374, "end_pos": 106778346, "strand": "-", "evidence": [ { "database": "Ensembl Gene", "id": "ENSBTAG00000017970", "url": "https://www.ensembl.org/id/ENSBTAG00000017970" } ] } } ], "crossref": [ { "id": "F6PUM3", "url": "https://alphafold.ebi.ac.uk/entry/F6PUM3", "database": "AlphaFoldDB", "categories": [] }, { "id": "cd09353", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd09353", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "cd09435", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd09435", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "768226", "url": "https://www.ncbi.nlm.nih.gov/gene/768226", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR001781", "url": "https://www.ebi.ac.uk/interpro/entry/IPR001781", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "PTHR24212", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR24212", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR24212:SF1", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR24212:SF1", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00412", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00412", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "A0A3Q1LQJ9", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1LQJ9", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A3Q1LQJ9-1", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1LQJ9-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "F6PUM3", "url": "https://www.uniprot.org/uniprotkb/F6PUM3", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "F6PUM3-1", "url": "https://www.uniprot.org/uniprotkb/F6PUM3-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MVCAPRSPRPLPPSVFPASLPARLDRDAESADSAARRPLADAARTLRPAPGLAMAAPRPPRAISVSAPVFYAPQKKFAPVVAPKPKVNPFRPGDSEPPPAAGAQRAQMGRVGEIPPPPPEDFPLPPPPVVGEADDAEGALGGAFPPPPPPIDEPFPPAPLEEEIFPSPPPPLVEEGGPEAPTQFPSQPREKVSSIDLEIDSLSSLLDDMTKNDPFKARVSSGYVPPPVTTPFISKSNTKPSTGGTAPLPPWKSPSSSQPVSQAQPQSQTQFHVQSQPQAKPQAPPQPVPLATTQPRGPLAPSPAPKFSPVTPKFTPVASKFSPGAPGGPGSQPHQKLGPPEAPSSTGTGSPQPPSFTYAQQKEKPQVQEKQHPVPPPTQNQNQVRPAGAPGPLTLKEVEELEQLTQKLMQDMEHPQKQSVPINESCGRCHQPLARSQPAVRALGQLFHITCFTCRQCEQQLQGQQFYSLEGAPYCEGCYTDTLEKCSTCGQPITDRMLRATGKAYHPQCFTCVVCACPLEGTSFIVDQANRPHCVPDYHKQYAPRCSVCAEPIMPEPGREETVRVVALDKNFHMKCYKCEDCGKPLSIEADDNGCFPLDGHVLCRKCHTARA", "length": 612, "header": "tr|F6PUM3-1|F6PUM3_BOVIN Isoform 1 of Zyxin OS=Bos taurus OX=9913 GN=ZYX PE=1 SV=1 CANONICAL=F6PUM3-1" }, "isoforms": [ { "isoform_ac": "A0A3Q1LQJ9-1", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1LQJ9/entry", "sequence": { "sequence": "MPQRIAEPGLAMAAPRPPRAISVSAPVFYAPQKKFAPVVAPKPKVNPFRPGDSEPPPAAGAQRAQMGRVGEIPPPPPEDFPLPPPPVVGEADDAEGALGGAFPPPPPPIDEPFPPAPLEEEIFPSPPPPLVEEGGPEAPTQFPSQPREKVSSIDLEIDSLSSLLDDMTKNDPFKARVSSGYVPPPVTTPFISKSNTKPSTGGTAPLPPWKSPSSSQPVSQAQPQSQTQFHVQSQPQAKPQAPPQPVPLATTQPRGPLAPSPAPKFSPVTPKFTPVASKFSPGAPGGPGSQPHQKLGPPEAPSSTGTGSPQPPSFTYAQQKEKPQVQEKQHPVPPPTQNQNQVRPAGAPGPLTLKEVEELEQLTQKLMQDMEHPQKQSVPINESCGRCHQPLARSQPAVRALGQLFHITCFTCRQCEQQLQGQQFYSLEGAPYCEGCYTDTLEKCSTCGQPITDRMLRATGKAYHPQCFTCVVCACPLEGTSFIVDQANRPHCVPDYHKQYAPRCSVCAEPIMPEPGREETVRVVALDKNFHMKCYKCEDCGKPLSIEADDNGCFPLDGHVLCRKCHTARA", "length": 570, "header": "tr|A0A3Q1LQJ9-1|F6PUM3_BOVIN Computationally mapped isoform of Zyxin OS=Bos taurus OX=9913 GN=ZYX PE=1 SV=1 CANONICAL=F6PUM3-1" }, "locus": { "chromosome": "4", "start_pos": 106787894, "end_pos": 106778677, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000077490.3", "url": "https://www.ensembl.org/id/ENSBTAT00000077490.3" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000059265.2", "url": "https://www.ensembl.org/id/ENSBTAP00000059265.2" } ] } }, { "isoform_ac": "F6PUM3-1", "url": "https://www.uniprot.org/uniprotkb/F6PUM3/entry", "sequence": { "sequence": "MVCAPRSPRPLPPSVFPASLPARLDRDAESADSAARRPLADAARTLRPAPGLAMAAPRPPRAISVSAPVFYAPQKKFAPVVAPKPKVNPFRPGDSEPPPAAGAQRAQMGRVGEIPPPPPEDFPLPPPPVVGEADDAEGALGGAFPPPPPPIDEPFPPAPLEEEIFPSPPPPLVEEGGPEAPTQFPSQPREKVSSIDLEIDSLSSLLDDMTKNDPFKARVSSGYVPPPVTTPFISKSNTKPSTGGTAPLPPWKSPSSSQPVSQAQPQSQTQFHVQSQPQAKPQAPPQPVPLATTQPRGPLAPSPAPKFSPVTPKFTPVASKFSPGAPGGPGSQPHQKLGPPEAPSSTGTGSPQPPSFTYAQQKEKPQVQEKQHPVPPPTQNQNQVRPAGAPGPLTLKEVEELEQLTQKLMQDMEHPQKQSVPINESCGRCHQPLARSQPAVRALGQLFHITCFTCRQCEQQLQGQQFYSLEGAPYCEGCYTDTLEKCSTCGQPITDRMLRATGKAYHPQCFTCVVCACPLEGTSFIVDQANRPHCVPDYHKQYAPRCSVCAEPIMPEPGREETVRVVALDKNFHMKCYKCEDCGKPLSIEADDNGCFPLDGHVLCRKCHTARA", "length": 612, "header": "tr|F6PUM3-1|F6PUM3_BOVIN Isoform 1 of Zyxin OS=Bos taurus OX=9913 GN=ZYX PE=1 SV=1 CANONICAL=F6PUM3-1" }, "locus": { "chromosome": "4", "start_pos": 106787894, "end_pos": 106779317, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000023912.7", "url": "https://www.ensembl.org/id/ENSBTAT00000023912.7" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000023912.5", "url": "https://www.ensembl.org/id/ENSBTAP00000023912.5" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [], "orthologs": [], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 7, "go_terms": [ { "name": "nucleus", "id": "GO:0005634", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005634", "evidence": [ { "database": "UniProtKB", "id": "F6PUM3", "url": "https://www.uniprot.org/uniprotkb/F6PUM3" } ], "pmid": "" }, { "name": "cytoplasm", "id": "GO:0005737", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005737", "evidence": [ { "database": "UniProtKB", "id": "F6PUM3", "url": "https://www.uniprot.org/uniprotkb/F6PUM3" } ], "pmid": "" }, { "name": "cytoskeleton", "id": "GO:0005856", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005856", "evidence": [ { "database": "UniProtKB", "id": "F6PUM3", "url": "https://www.uniprot.org/uniprotkb/F6PUM3" } ], "pmid": "" }, { "name": "focal adhesion", "id": "GO:0005925", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005925", "evidence": [ { "database": "UniProtKB", "id": "F6PUM3", "url": "https://www.uniprot.org/uniprotkb/F6PUM3" } ], "pmid": "" }, { "name": "adherens junction", "id": "GO:0005912", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005912", "evidence": [ { "database": "UniProtKB", "id": "F6PUM3", "url": "https://www.uniprot.org/uniprotkb/F6PUM3" } ], "pmid": "" }, { "name": "stress fiber", "id": "GO:0001725", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0001725", "evidence": [ { "database": "UniProtKB", "id": "F6PUM3", "url": "https://www.uniprot.org/uniprotkb/F6PUM3" } ], "pmid": "" }, { "name": "phagocytic vesicle", "id": "GO:0045335", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0045335", "evidence": [ { "database": "UniProtKB", "id": "F6PUM3", "url": "https://www.uniprot.org/uniprotkb/F6PUM3" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 4, "go_terms": [ { "name": "integrin-mediated signaling pathway", "id": "GO:0007229", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007229", "evidence": [ { "database": "UniProtKB", "id": "F6PUM3", "url": "https://www.uniprot.org/uniprotkb/F6PUM3" } ], "pmid": "" }, { "name": "cell-matrix adhesion", "id": "GO:0007160", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007160", "evidence": [ { "database": "UniProtKB", "id": "F6PUM3", "url": "https://www.uniprot.org/uniprotkb/F6PUM3" } ], "pmid": "" }, { "name": "transforming growth factor beta receptor signaling pathway", "id": "GO:0007179", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007179", "evidence": [ { "database": "UniProtKB", "id": "F6PUM3", "url": "https://www.uniprot.org/uniprotkb/F6PUM3" } ], "pmid": "" }, { "name": "stress fiber assembly", "id": "GO:0043149", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0043149", "evidence": [ { "database": "UniProtKB", "id": "F6PUM3", "url": "https://www.uniprot.org/uniprotkb/F6PUM3" } ], "pmid": "" } ] }, { "name": "Molecular Function", "total": 1, "go_terms": [ { "name": "metal ion binding", "id": "GO:0046872", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0046872", "evidence": [ { "database": "UniProtKB", "id": "F6PUM3", "url": "https://www.uniprot.org/uniprotkb/F6PUM3" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 423, "end_pos": 425, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "F6PUM3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F6PUM3" }, { "id": "PS50023", "database": "PROSITE", "url": "https://prosite.expasy.org/PS50023" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "LIM zinc-binding", "eco_id": "ECO_0000259", "start_pos": 424, "end_pos": 483, "start_aa": "Glu", "end_aa": "Leu", "glycosite_overlap": [] } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 423, "end_pos": 425 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ], "tool_support": { "graph_view": "yes" } }, { "uniprot_canonical_ac": "F6R700-1", "uniprot_ac": "F6R700", "uniprot_id": "F6R700_BOVIN", "mass": { "chemical_mass": 41548.0, "monoisotopic_mass": 41548.0 }, "refseq": { "ac": "XP_015315821", "name": "membrane progestin receptor alpha isoform X2", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_015315821" }, "gene_names": [ { "name": "PAQR7", "type": "recommended", "evidence": [ { "id": "F6R700", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F6R700" } ] }, { "name": "PAQR7", "type": "synonym", "evidence": [ { "id": "XP_015315821", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_015315821" } ] } ], "protein_names": [ { "name": "Progestin and adipoQ receptor family member 7", "type": "synonym", "evidence": [ { "id": "F6R700", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F6R700/entry#names_and_taxonomy" } ] }, { "name": "membrane progestin receptor alpha isoform X2", "type": "synonym", "evidence": [ { "id": "XP_015315821", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_015315821" } ] } ], "function": [], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Bos taurus", "taxid": 9913, "evidence": [ { "database": "UniProtKB", "id": "F6R700", "url": "https://www.uniprot.org/uniprotkb/F6R700" } ], "common_name": "Bovine", "glygen_name": "Bovine", "reference_species": "Bos taurus [9913]" } ], "gene": [ { "name": "PAQR7", "url": "https://www.uniprot.org/uniprotkb/F6R700", "locus": { "chromosome": "2", "start_pos": 127237892, "end_pos": 127207474, "strand": "-", "evidence": [ { "database": "Ensembl Gene", "id": "ENSBTAG00000021787", "url": "https://www.ensembl.org/id/ENSBTAG00000021787" } ] } } ], "crossref": [ { "id": "F6R700", "url": "https://alphafold.ebi.ac.uk/entry/F6R700", "database": "AlphaFoldDB", "categories": [] }, { "id": "522932", "url": "https://www.ncbi.nlm.nih.gov/gene/522932", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR004254", "url": "https://www.ebi.ac.uk/interpro/entry/IPR004254", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR029286", "url": "https://www.ebi.ac.uk/interpro/entry/IPR029286", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "PTHR14526", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR14526", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR14526:SF2", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR14526:SF2", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR20855", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR20855", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR20855:SF41", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR20855:SF41", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF03006", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF03006", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF15334", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF15334", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "XP_015315821", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_015315821", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0AAA9SGL5", "url": "https://www.uniprot.org/uniprotkb/A0AAA9SGL5", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0AAA9SGL5-1", "url": "https://www.uniprot.org/uniprotkb/A0AAA9SGL5-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0AAF6Z9R0", "url": "https://www.uniprot.org/uniprotkb/A0AAF6Z9R0", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0AAF6Z9R0-1", "url": "https://www.uniprot.org/uniprotkb/A0AAF6Z9R0-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "F6R700", "url": "https://www.uniprot.org/uniprotkb/F6R700", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "F6R700-1", "url": 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127237669, "end_pos": 127221758, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000029039.5", "url": "https://www.ensembl.org/id/ENSBTAT00000029039.5" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000029039.4", "url": "https://www.ensembl.org/id/ENSBTAP00000029039.4" } ] } }, { "isoform_ac": "F6R700-1", "url": "https://www.uniprot.org/uniprotkb/F6R700/entry", "sequence": { "sequence": "MRQRRSSPPAQPTAMATIVAQKLSHLLPSLRQVHQEPQPSVPSEPVFTVDRAEVPPLFWKPYIYVGYRPLHRTWRFYFRTLFQQHNEAVNVWTHLLAALVLLLRLAIFVGTVDFWGDPHALPLFIIVLASFTYLSLSALAHLLQAKSEFWHYSFFFLDYVGVAVYQFGSALAHFYYAIEPAWHAQVQTIFLPTAAFLAWLSCTGSCYNKYIQKPGLLGRTCQEVPSALAYALDISPVAHRILVSPDPATDDPALLYHKCQVVFFLLAAAFFSAFMPERWFPGCCHVFGQGHQLFHVFLVLCTLAQLEAVALDYEARRSIYEPLHTRWPHNFSGLFLLTVGSSILTAFLLSQLVRRKLDLHRKTQ", "length": 364, "header": "tr|F6R700-1|F6R700_BOVIN Isoform 1 of Progestin and adipoQ receptor family member 7 OS=Bos taurus OX=9913 GN=PAQR7 PE=3 SV=1 CANONICAL=F6R700-1" }, "locus": { "chromosome": "2", 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"pmid": "" } ] }, { "name": "Molecular Function", "total": 2, "go_terms": [ { "name": "metal ion binding", "id": "GO:0046872", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0046872", "evidence": [ { "database": "UniProtKB", "id": "F6R700", "url": "https://www.uniprot.org/uniprotkb/F6R700" } ], "pmid": "" }, { "name": "steroid binding", "id": "GO:0005496", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005496", "evidence": [ { "database": "UniProtKB", "id": "F6R700", "url": "https://www.uniprot.org/uniprotkb/F6R700" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 1, "go_terms": [ { "name": "oogenesis", "id": "GO:0048477", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0048477", "evidence": [ { "database": "UniProtKB", "id": "F6R700", "url": "https://www.uniprot.org/uniprotkb/F6R700" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 330, "end_pos": 332, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], 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"tr|F6QY62-1|F6QY62_BOVIN Isoform 1 of Integrator complex subunit 4 OS=Bos taurus OX=9913 GN=INTS4 PE=3 SV=1 CANONICAL=F6QY62-1" }, "isoforms": [ { "isoform_ac": "E1BLD2-1", "url": "https://www.uniprot.org/uniprotkb/E1BLD2/entry", "sequence": { "sequence": "MAAHLKKRVYEEFTKVVQQQQEEVATKKLRMTKPSKSAALHIDLCKATSPADALQYLLQFARKPVEAESVEGVVRILLEHYYKENDPSVRLKIASLLGLLSKTAGFSPDCIMDDAINILQNEKSHQVLAQLLDTLLAIGTKLPENQAIQMRLVDVACKHLTDTSHGVRNKCLQLLGNLGSLEKNVTKDAEGLAVRDVQKIIGDYFNDQDPRVRTAAIKAMLQLHERGLKLHQTIYNQACKLLSDDYEQVRSAAVQLIWVVSQLYPESIVPIPSSNEEIRLVDDAFGKICHMVSDGSWMVRVQAAKLLGSMEQVSSHFLEQTLDKKLMSDLRRKRTAHERAKELYSSGEFSSGRKWGDDAPKEEIDTGAVNLIESGACGAFVHGLEDEMYEVRIAAVEALCMLAQSSPSFAEKCLDFLVDMFNDEIEEVRLQSIHTMRKISNNITLREDQLDTVLAVLEDSSRDIREALHELLCCTNVSTKEGIHLALVELLKNLTKYPTDRDSIWKCLKFLGSRHPTLVLPLVPELLSTHPFFDTAEPDMDDPAYIAVLVLIFNAAKTCPTMPALFSDHTFRHYAYLRDSLSHLVPALRLPGRKLVSSGLSPNITPHEDPSHQFLQQSLERVYSLQHLDPQGTQELLEFTIRDLQRLGELQSELAGVADFSATYLRCQLLLIKIMEETYKMEFMYSGVENKQVVIIHHMRLQAKALQLIVTARTARGVDPLFGMCEKFLQEVDFFQRCFIADLPHLQDSFVDRLLDLMPRLMTSKPAEVVKILQAMLRQSTFLHLPLPEQIHKASATIIEPAGESDNPLRFTSGLVVALDVDATLEHVQDPQNTVKVQVLYPDGQAQMIHPKPADFRNPGPGRHRLITQVFLSHTAWTEPCQVEVRLLLAYNSSSRIPKSPWIEGGEMSPQVETGIEGTIPFSKSVKVYIMPKPARR", "length": 937, "header": "tr|E1BLD2-1|F6QY62_BOVIN Computationally mapped isoform of Integrator complex subunit 4 OS=Bos taurus OX=9913 GN=INTS4 PE=3 SV=3 CANONICAL=F6QY62-1" }, "locus": { "chromosome": "29", "start_pos": 18148367, "end_pos": 18041230, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000061534.5", "url": "https://www.ensembl.org/id/ENSBTAT00000061534.5" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000053790.3", "url": "https://www.ensembl.org/id/ENSBTAP00000053790.3" } ] } }, { "isoform_ac": "F6QY62-1", "url": "https://www.uniprot.org/uniprotkb/F6QY62/entry", "sequence": { "sequence": "MAAHLKKRVYEEFTKVVQEEVATKKLRMTKPSKSAALHIDLCKATSPADALQYLLQFARKPVEAESVEGVVRILLEHYYKENDPSVRLKIASLLGLLSKTAGFSPDCIMDDAINILQNEKSHQVLAQLLDTLLAIGTKLPENQAIQMRLVDVACKHLTDTSHGVRNKCLQLLGNLGSLEKNVTKDAEGLAVRDVQKIIGDYFNDQDPRVRTAAIKAMLQLHERGLKLHQTIYNQACKLLSDDYEQVRSAAVQLIWVVSQLYPESIVPIPSSNEEIRLVDDAFGKICHMVSDGSWMVRVQAAKLLGSMEQVSSHFLEQTLDKKLMSDLRRKRTAHERAKELYSSGEFSSGRKWGDDAPKEEIDTGAVNLIESGACGAFVHGLEDEMYEVRIAAVEALCMLAQSSPSFAEKCLDFLVDMFNDEIEEVRLQSIHTMRKISNNITLREDQLDTVLAVLEDSSRDIREALHELLCCTNVSTKEGIHLALVELLKNLTKYPTDRDSIWKCLKFLGSRHPTLVLPLVPELLSTHPFFDTAEPDMDDPAYIAVLVLIFNAAKTCPTMPALFSDHTFRHYAYLRDSLSHLVPALRLPGRKLVSSGLSPNITPHEDPSHQFLQQSLERVYSLQHLDPQGTQELLEFTIRDLQRLGELQSELAGVADFSATYLRCQLLLIKALQEKLWNVAAPLYLKQSDLASAAAKQIMEETYKMEFMYSGVENKQVVIIHHMRLQAKALQLIVTARTARGVDPLFGMCEKFLQEVDFFQRCFIADLPHLQDSFVDRLLDLMPRLMTSKPAEVVKILQAMLRQSTFLHLPLPEQIHKASATIIEPAGESDNPLRFTSGLVVALDVDATLEHVQDPQNTVKVQVLYPDGQAQMIHPKPADFRNPGPGRHRLITQVFLSHTAWTEPCQVEVRLLLAYNSSSRIPKSPWIEGGEMSPQVETGIEGTIPFSKSVKVYIMPKPARR", "length": 961, "header": "tr|F6QY62-1|F6QY62_BOVIN Isoform 1 of Integrator complex subunit 4 OS=Bos taurus OX=9913 GN=INTS4 PE=3 SV=1 CANONICAL=F6QY62-1" }, "locus": { "chromosome": "29", "start_pos": 18148367, "end_pos": 18041230, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000013891.6", "url": "https://www.ensembl.org/id/ENSBTAT00000013891.6" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000013891.5", "url": "https://www.ensembl.org/id/ENSBTAP00000013891.5" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [ { "id": "R-BTA-6807505", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-BTA-6807505", "resource": "Reactome", "description": "RNA polymerase II transcribes snRNA genes" } ], "orthologs": [], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 4, "go_terms": [ { "name": "cytoplasm", "id": "GO:0005737", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005737", "evidence": [ { "database": "UniProtKB", "id": "F6QY62", "url": "https://www.uniprot.org/uniprotkb/F6QY62" } ], "pmid": "" }, { "name": "integrator complex", "id": "GO:0032039", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0032039", "evidence": [ { "database": "UniProtKB", "id": "F6QY62", "url": "https://www.uniprot.org/uniprotkb/F6QY62" } ], "pmid": "" }, { "name": "nucleolus", "id": "GO:0005730", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005730", "evidence": [ { "database": "UniProtKB", "id": "F6QY62", "url": "https://www.uniprot.org/uniprotkb/F6QY62" } ], "pmid": "" }, { "name": "INTAC complex", "id": "GO:0160232", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0160232", "evidence": [ { "database": "UniProtKB", "id": "F6QY62", "url": "https://www.uniprot.org/uniprotkb/F6QY62" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 3, "go_terms": [ { "name": "snRNA processing", "id": "GO:0016180", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016180", "evidence": [ { "database": "UniProtKB", "id": "F6QY62", "url": "https://www.uniprot.org/uniprotkb/F6QY62" } ], "pmid": "" }, { "name": "regulation of transcription elongation by RNA polymerase II", "id": "GO:0034243", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0034243", "evidence": [ { "database": "UniProtKB", "id": "F6QY62", "url": "https://www.uniprot.org/uniprotkb/F6QY62" } ], "pmid": "" }, { "name": "RNA polymerase II transcription initiation surveillance", "id": "GO:0160240", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0160240", "evidence": [ { "database": "UniProtKB", "id": "F6QY62", "url": "https://www.uniprot.org/uniprotkb/F6QY62" } ], "pmid": "" } ] }, { "name": "Molecular Function", "total": 1, "go_terms": [ { "name": "protein-macromolecule adaptor activity", "id": "GO:0030674", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030674", "evidence": [ { "database": "UniProtKB", "id": "F6QY62", "url": "https://www.uniprot.org/uniprotkb/F6QY62" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 181, "end_pos": 183, "annotation": "n_glycosylation_sequon" }, { "start_pos": 439, "end_pos": 441, "annotation": "n_glycosylation_sequon" }, { "start_pos": 473, "end_pos": 475, "annotation": "n_glycosylation_sequon" }, { "start_pos": 490, "end_pos": 492, "annotation": "n_glycosylation_sequon" }, { "start_pos": 600, "end_pos": 602, "annotation": "n_glycosylation_sequon" }, { "start_pos": 916, "end_pos": 918, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "F6QY62", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F6QY62" }, { "id": "PF24493", "database": "Pfam", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF24493" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "INTS4 8 helical bundle", "eco_id": "ECO_0000259", "start_pos": 610, "end_pos": 812, "start_aa": "Gln", "end_aa": "Pro", "glycosite_overlap": [] }, { "evidence": [ { "id": "F6QY62", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F6QY62" }, { "id": "PF25458", "database": "Pfam", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF25458" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "Integrator complex subunit 4/Protein SIEL C-terminal Ig-like", "eco_id": "ECO_0000259", "start_pos": 821, "end_pos": 958, "start_aa": "Thr", "end_aa": "Pro", "glycosite_overlap": [] } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 181, "end_pos": 183 }, { "start_pos": 439, "end_pos": 441 }, { "start_pos": 473, "end_pos": 475 }, { "start_pos": 490, "end_pos": 492 }, { "start_pos": 600, "end_pos": 602 }, { "start_pos": 916, "end_pos": 918 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ], "tool_support": { "graph_view": "yes" } }, { "uniprot_canonical_ac": "F6QGC9-1", "uniprot_ac": "F6QGC9", "uniprot_id": "F6QGC9_BOVIN", "mass": { "chemical_mass": 79037.0, "monoisotopic_mass": 79037.0 }, "refseq": {}, "gene_names": [ { "name": "CAMTA1", "type": "recommended", "evidence": [ { "id": "F6QGC9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F6QGC9" } ] } ], "protein_names": [ { "name": "Calmodulin binding transcription activator 1", "type": "synonym", "evidence": [ { "id": "F6QGC9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F6QGC9/entry#names_and_taxonomy" } ] } ], "function": [], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Bos taurus", "taxid": 9913, "evidence": [ { "database": "UniProtKB", "id": "F6QGC9", "url": "https://www.uniprot.org/uniprotkb/F6QGC9" } ], "common_name": "Bovine", "glygen_name": "Bovine", "reference_species": "Bos taurus [9913]" } ], "gene": [ { "name": "CAMTA1", "url": "https://www.uniprot.org/uniprotkb/F6QGC9", "locus": { "chromosome": "16", "start_pos": 45632541, "end_pos": 45650798, "strand": "+", "evidence": [ { "database": "Ensembl Gene", "id": "ENSBTAG00000014602", "url": "https://www.ensembl.org/id/ENSBTAG00000014602" } ] } } ], "crossref": [ { "id": "F6QGC9", "url": "https://alphafold.ebi.ac.uk/entry/F6QGC9", "database": "AlphaFoldDB", "categories": [] }, { "id": "ENSBTAG00000014602", "url": "https://bgee.org/?page=gene&gene_id=ENSBTAG00000014602", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "cd23767", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd23767", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "IPR002110", "url": "https://www.ebi.ac.uk/interpro/entry/IPR002110", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR036770", "url": "https://www.ebi.ac.uk/interpro/entry/IPR036770", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "F1MNR3", "url": "https://www.orthodb.org/?gene=F1MNR3", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR23335", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR23335", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR23335:SF11", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR23335:SF11", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF12796", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF12796", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "F1MNR3", "url": "https://www.uniprot.org/uniprotkb/F1MNR3", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "F1MNR3-1", "url": "https://www.uniprot.org/uniprotkb/F1MNR3-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "F6QGC9", "url": "https://www.uniprot.org/uniprotkb/F6QGC9", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "F6QGC9-1", "url": "https://www.uniprot.org/uniprotkb/F6QGC9-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MSILERLEQMERRMAEMTGSQQHKQGSGGGSSGGGTGSGNGGSQAQCASGPGTLGSCFESRVVVVCEKMMSRACWAKSKHLIHSKTFRGMTLLHLAAAQGYATLIQTLIKWRTKHADSIDLELEVDPLNVDHFSCTPLMWACALGHLEAAVVLYKWDRRAISIPDSLGRLPLGIARSRGHVKLAECLEHLQRDEQAQLGQNPRIHCPAGDEPSTESWVSQWHSEAINSPEIPKGVTVIASTNPELRRPRSEPSNYYSSESHKDYPAPKKHKLNPEYFQARQEKLLSTALSLEQPNIRKQSPSSKQPVPETISPSEGLRDYSREISPPTPETAGFLHASASQPVVKWNPKDLYIGVSTVQVTGNPKGTSVGKDVTPSQVRPREPMSVLMMANREVVNSELGSYRDGTESEECSQPMDDIQVNMMTLAEHIIEATPERIKQENFVPLESPALERTDVATISSTMSWLAGYLADVDHLPNAAQIRSAYNEPLTPSSNTSLSPVGSPVSEITFEKPSLPSAADWSEFLSASTSEKVENEFAQLTLSDHEQRELYEAARLVQTAFRKYKGRPLREQQEVAAAVIQRCYRKYKQLLLVPSQYALYKKMTQAAILIQSKFRSYYEQKKFQQSRRAAVLIQKFYRSYKKCGKRRQARRTAVIVQQKLRSSLLTKKQDQAARKIMRFLRRCRHRVKELKKAKELEDIQQHPLAM", "length": 705, "header": "tr|F6QGC9-1|F6QGC9_BOVIN Isoform 1 of Calmodulin binding transcription activator 1 OS=Bos taurus OX=9913 GN=CAMTA1 PE=4 SV=2 CANONICAL=F6QGC9-1" }, "isoforms": [ { "isoform_ac": "F1MNR3-1", "url": "https://www.uniprot.org/uniprotkb/F1MNR3/entry", "sequence": { "sequence": "MSILERLEQMERRMAEMTGSQQHKQGSGGGSSGGGTGSGNGGSQAQCASGPGTLGSCFESRVVVVCEKMMSRACWAKSKHLIHSKTFRGMTLLHLAAAQGYATLIQTLIKWRTKHADSIDLELEVDPLNVDHFSCTPLMWACALGHLEAAVVLYKWDRRAISIPDSLGRLPLGIARSRGHVKLAECLEHLQRDEQAQLGQNPRIHCPAGDEPSTESWVSQWHSEAINSPEIPKGVTVIASTNPELRRPRSEPSNYYSSESHKDYPAPKKHKLNPEYFQARQEKLLSTALSLEQPNIRKQSPSSKQPVPETISPSEGLRDYSREISPPTPETAGFLHASASQPVVKWNPKDLYIGVSTVQVTGNPKGTSVGKDVTPSQVRPREPMSVLMMANREVVNSELGSYRDGTESEECSQPMDDIQVNMMTLAEHIIEATPERIKQENFVPLESPALERTDVATISSTMSWLAGYLADVDHLPNAAQIRSAYNEPLTPSSNTSLSPVGSPVSEITFEKPSLPSAADWSEFLSASTSEKVENEFAQLTLSDHEQRELYEAARLVQTAFRKYKGRPLREQQEVAAAVIQRCYRKYKQLTWIALKYALYKKMTQAAILIQSKFRSYYEQKKFQQSRRAAVLIQKFYRSYKKCGKRRQARRTAVIVQQKLRSSLLTKKQDQAARKIMRFLRRCRHRK", "length": 686, "header": "tr|F1MNR3-1|F6QGC9_BOVIN Computationally mapped isoform of Calmodulin binding transcription activator 1 OS=Bos taurus OX=9913 GN=CAMTA1 PE=4 SV=5 CANONICAL=F6QGC9-1" }, "locus": { "chromosome": "16", "start_pos": 45650784, "end_pos": 45627941, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000061635.5", "url": "https://www.ensembl.org/id/ENSBTAT00000061635.5" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000053411.5", "url": "https://www.ensembl.org/id/ENSBTAP00000053411.5" } ] } }, { "isoform_ac": "F6QGC9-1", "url": "https://www.uniprot.org/uniprotkb/F6QGC9/entry", "sequence": { "sequence": "MSILERLEQMERRMAEMTGSQQHKQGSGGGSSGGGTGSGNGGSQAQCASGPGTLGSCFESRVVVVCEKMMSRACWAKSKHLIHSKTFRGMTLLHLAAAQGYATLIQTLIKWRTKHADSIDLELEVDPLNVDHFSCTPLMWACALGHLEAAVVLYKWDRRAISIPDSLGRLPLGIARSRGHVKLAECLEHLQRDEQAQLGQNPRIHCPAGDEPSTESWVSQWHSEAINSPEIPKGVTVIASTNPELRRPRSEPSNYYSSESHKDYPAPKKHKLNPEYFQARQEKLLSTALSLEQPNIRKQSPSSKQPVPETISPSEGLRDYSREISPPTPETAGFLHASASQPVVKWNPKDLYIGVSTVQVTGNPKGTSVGKDVTPSQVRPREPMSVLMMANREVVNSELGSYRDGTESEECSQPMDDIQVNMMTLAEHIIEATPERIKQENFVPLESPALERTDVATISSTMSWLAGYLADVDHLPNAAQIRSAYNEPLTPSSNTSLSPVGSPVSEITFEKPSLPSAADWSEFLSASTSEKVENEFAQLTLSDHEQRELYEAARLVQTAFRKYKGRPLREQQEVAAAVIQRCYRKYKQLLLVPSQYALYKKMTQAAILIQSKFRSYYEQKKFQQSRRAAVLIQKFYRSYKKCGKRRQARRTAVIVQQKLRSSLLTKKQDQAARKIMRFLRRCRHRVKELKKAKELEDIQQHPLAM", "length": 705, "header": "tr|F6QGC9-1|F6QGC9_BOVIN Isoform 1 of Calmodulin binding transcription activator 1 OS=Bos taurus OX=9913 GN=CAMTA1 PE=4 SV=2 CANONICAL=F6QGC9-1" }, "locus": { "chromosome": "16", "start_pos": 45650784, "end_pos": 45621525, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000019436.8", "url": "https://www.ensembl.org/id/ENSBTAT00000019436.8" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000019436.7", "url": "https://www.ensembl.org/id/ENSBTAP00000019436.7" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [], "orthologs": [], "go_annotation": {}, "pro_annotation": [], "site_annotation": [ { "start_pos": 494, "end_pos": 496, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 494, "end_pos": 496 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ], "tool_support": { "graph_view": "yes" } }, { "uniprot_canonical_ac": "F1N739-1", "uniprot_ac": "F1N739", "uniprot_id": "F1N739_BOVIN", "mass": { "chemical_mass": 176435.0, "monoisotopic_mass": 176435.0 }, "refseq": {}, "gene_names": [ { "name": "ROBO1", "type": "recommended", "evidence": [ { "id": "F1N739", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1N739" } ] } ], "protein_names": [ { "name": "Roundabout guidance receptor 1", "type": "synonym", "evidence": [ { "id": "F1N739", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1N739/entry#names_and_taxonomy" } ] } ], "function": [], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Bos taurus", "taxid": 9913, "evidence": [ { "database": "UniProtKB", "id": "F1N739", "url": "https://www.uniprot.org/uniprotkb/F1N739" } ], "common_name": "Bovine", "glygen_name": "Bovine", "reference_species": "Bos taurus [9913]" } ], "gene": [ { "name": "ROBO1", "url": "https://www.uniprot.org/uniprotkb/F1N739", "locus": { "chromosome": "1", "start_pos": 26116520, "end_pos": 27412646, "strand": "+", "evidence": [ { "database": "Ensembl Gene", "id": "ENSBTAG00000009851", "url": "https://www.ensembl.org/id/ENSBTAG00000009851" } ] } } ], "crossref": [ { "id": "ENSBTAG00000009851", "url": "https://bgee.org/?page=gene&gene_id=ENSBTAG00000009851", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "cd00063", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd00063", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "cd05724", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd05724", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "cd05725", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd05725", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "cd05726", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd05726", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "cd07693", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd07693", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "cd20952", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd20952", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "536815", "url": "https://www.ncbi.nlm.nih.gov/gene/536815", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR003598", "url": "https://www.ebi.ac.uk/interpro/entry/IPR003598", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR003599", "url": "https://www.ebi.ac.uk/interpro/entry/IPR003599", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR003961", "url": "https://www.ebi.ac.uk/interpro/entry/IPR003961", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR007110", "url": "https://www.ebi.ac.uk/interpro/entry/IPR007110", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR013098", "url": "https://www.ebi.ac.uk/interpro/entry/IPR013098", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR013106", "url": "https://www.ebi.ac.uk/interpro/entry/IPR013106", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR013783", "url": "https://www.ebi.ac.uk/interpro/entry/IPR013783", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR032986", "url": "https://www.ebi.ac.uk/interpro/entry/IPR032986", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR036116", "url": "https://www.ebi.ac.uk/interpro/entry/IPR036116", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR036179", "url": "https://www.ebi.ac.uk/interpro/entry/IPR036179", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR051170", "url": "https://www.ebi.ac.uk/interpro/entry/IPR051170", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "bta:536815", "url": "https://www.genome.jp/dbget-bin/www_bget?bta:536815", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "F1N279", "url": "https://www.orthodb.org/?gene=F1N279", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "F1N739", "url": "https://www.orthodb.org/?gene=F1N739", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR12231", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR12231", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR12231:SF243", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR12231:SF243", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00041", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00041", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF07679", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF07679", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF13927", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF13927", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "R-BTA-376176", "url": "https://www.reactome.org/PathwayBrowser/#R-BTA-376176", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "R-BTA-428890", "url": "https://www.reactome.org/PathwayBrowser/#R-BTA-428890", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "R-BTA-8985586", "url": "https://www.reactome.org/PathwayBrowser/#R-BTA-8985586", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "R-BTA-9010553", "url": "https://www.reactome.org/PathwayBrowser/#R-BTA-9010553", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "A0AAA9SYD9", "url": "https://www.uniprot.org/uniprotkb/A0AAA9SYD9", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0AAA9SYD9-1", "url": "https://www.uniprot.org/uniprotkb/A0AAA9SYD9-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0AAA9T3N6", "url": "https://www.uniprot.org/uniprotkb/A0AAA9T3N6", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0AAA9T3N6-1", "url": "https://www.uniprot.org/uniprotkb/A0AAA9T3N6-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "F1N279", "url": "https://www.uniprot.org/uniprotkb/F1N279", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "F1N279-1", "url": "https://www.uniprot.org/uniprotkb/F1N279-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "F1N739", "url": "https://www.uniprot.org/uniprotkb/F1N739", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "F1N739-1", "url": "https://www.uniprot.org/uniprotkb/F1N739-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MIAEPAHFYLFGLICLCSGSRLRQEDFPPRIVEHPSDLIVSKGEPATLNCKAEGRPTPTIEWYKGGERVETDKDDPRSHRMLLPSGSLFFLRIVHGRKSRPDEGVYVCVARNYLGEAVSHNASLEVAILRDDFRQNPSDVMVAVGEPAVMECQPPRGHPEPTISWKKDGSPLDDKDERITIRGGKLMITYTRKSDAGKYVCVGTNMVGERESEVAELTVLERPSFVKRPSNLAVTVDDSAEFKCEARGDPVPTVRWRKDDGELPKSRYEIRDDHTLKIRKVTAGDMGSYTCVAENMVGKAEASATLTVQVGSEPPHFVVKPRDQVVALGRTVTFQCEATGNPQPAIFWRREGSQNLLFSYQPPQSSSRFSVSQTGDLTITNVQRSDVGYYICQTLNVAGSIITKAYLEVTDVIADRPPPVIRQGPVNQTVAVDGTLVLSCVATGSPVPTILWRKDGVLVSTQDSRIKQLETGVLQIRYAKLGDTGRYTCIASTPSGEATWSAYIEVQEFGVPVQPPRPTDPNLIPSAPSKPEVTDVSRNTVTLSWQPNLNSGATPTSYIIEAFSHASGSSWQTVAENVKTETFAIKGLKPNAIYLFLVRAANAYGISDPSQISDPVKTQDVPPTSQGVDHKQVQRELGNVVLHLHNPTILSSSSIEVHWTVDQQSQYIQGYKVLYRPSGANHGESEWLVFEVRTPTKNSVVIPDLKKGVNYEIKARPFFNEFQGADSEIKFAKTLEEAPSAPPQSVTVSKNDGNGTAILVSWQPPPEDTQNGMVQEYKVWCLGNETRYHINKTVDGSTFSVVIPSLVPGIRYSVEVAASTGAGSGVKSEPQFIQLDSHGNPVSPEDQVSLAQQISDVVKQPAFIAGIGAACWIILMVFSIWLYRHRKKRNGLASTYAGIRKVPSFTFTPTVTYQRGGEAVSSGGRPGLLNISEPATQPWLADTWPNTGNNHNDCSINCCTAGNGNSDSNLTTYSRPADCIANYNNQLDNKQTNLMLPESTVYGDVDLSNKINEMKTFNSPNLKDGRFVNPSGQPTPYATTQLIQSNLSNNMNNGSGDSGEKHWKPPGQQKQEVAPIQYNIMEQNKLNKDYRANDTIAPTIPYNQSYDQNTGGSYNSSDRGSSTSGSQGHKKGARTPKVPKQGGMNWADLLPPPPAHPPPHSNSEEYSISVDESYDQEMPCPVPPARMYLQQGELEEEEDERGPTPPVRGAASSPAAVSYSHQSTATLTPSPQEELQPMLQDCPEEVGHGQHQPDRRRQPVSPPPPPRPISPPHTYGYISGPLVSDMDTDAPEEEEDEADMEVAKMQTRRLLLRGLEQTPASSVGDLESSVTGSMINGWGSASEEDNISSGRSSVSSSDGSFFTDADFAQAVAAAAEYAGLKVARRQMQDAAGRRHFHASQCPRPTSPVSTDSNVSAAVVQKARPAKKQKHQPGHLRREAYTDDLPPPPVPPPAIKSPTAQSKAQLEVRPVMVPKLPSIEARTDRSSDRKGGNYKGREVLDGRQVADMRPNPGDAREAQEQPNDGKGRGNKAAKRDLPPAKAHLIQEDILPYCRPTFPTSNNPRDPSSSSSMSSRGSGSRQREQANVGRRNIAEMQVLGGYEREDNNEELEETES", "length": 1614, "header": "tr|F1N739-1|F1N739_BOVIN Isoform 1 of Roundabout guidance receptor 1 OS=Bos taurus OX=9913 GN=ROBO1 PE=3 SV=4 CANONICAL=F1N739-1" }, "isoforms": [ { "isoform_ac": "A0AAA9SYD9-1", "url": "https://www.uniprot.org/uniprotkb/A0AAA9SYD9/entry", "sequence": { "sequence": "MKWTHAPFLAIISLLSLSKSHLFLAQLIPDPEDVERGKDNGTPIPTSDNDDNSLGYTGSRLRQEDFPPRIVEHPSDLIVSKGEPATLNCKAEGRPTPTIEWYKGGERVETDKDDPRSHRMLLPSGSLFFLRIVHGRKSRPDEGVYVCVARNYLGEAVSHNASLEVAILRDDFRQNPSDVMVAVGEPAVMECQPPRGHPEPTISWKKDGSPLDDKDERITIRGGKLMITYTRKSDAGKYVCVGTNMVGERESEVAELTVLERPSFVKRPSNLAVTVDDSAEFKCEARGDPVPTVRWRKDDGELPKSRYEIRDDHTLKIRKVTAGDMGSYTCVAENMVGKAEASATLTVQVGSEPPHFVVKPRDQVVALGRTVTFQCEATGNPQPAIFWRREGSQNLLFSYQPPQSSSRFSVSQTGDLTITNVQRSDVGYYICQTLNVAGSIITKAYLEVTDVIADRPPPVIRQGPVNQTVAVDGTLVLSCVATGSPVPTILWRKDGVLVSTQDSRIKQLETGVLQIRYAKLGDTGRYTCIASTPSGEATWSAYIEVQEFGVPVQPPRPTDPNLIPSAPSKPEVTDVSRNTVTLSWQPNLNSGATPTSYIIEAFSHASGSSWQTVAENVKTETFAIKGLKPNAIYLFLVRAANAYGISDPSQISDPVKTQDVPPTSQGVDHKQVQRELGNVVLHLHNPTILSSSSIEVHWTVDQQSQYIQGYKVLYRPSGANHGESEWLVFEVRTPTKNSVVIPDLKKGVNYEIKARPFFNEFQGADSEIKFAKTLEEAPSAPPQSVTVSKNDGNGTAILVSWQPPPEDTQNGMVQEYKVWCLGNETRYHINKTVDGSTFSVVIPSLVPGIRYSVEVAASTGAGSGVKSEPQFIQLDSHGNPVSPEDQVSLAQQISDVVKQPAFIAGIGAACWIILMVFSIWLYRHRKKRNGLASTYAGIRKVPSFTFTPTVTYQRGGEAVSSGGRPGLLNISEPATQPWLADTWPNTGNNHNDCSINCCTAGNGNSDSNLTTYSRPADCIANYNNQLDNKQTNLMLPESTVYGDVDLSNKINEMKTFNSPNLKDGRFVNPSGQPTPYATTQLIQSNLSNNMNNGSGDSGEKHWKPPGQQKQEVAPIQYNIMEQNKLNKDYRANDTIAPTIPYNQSYDQNTGGSYNSSDRGSSTSGSQGHKKGARTPKVPKQGGMNWADLLPPPPAHPPPHSNSEEYSISVDESYDQEMPCPVPPARMYLQQGELEEEEDERGPTPPVRGAASSPAAVSYSHQSTATLTPSPQEELQPMLQDCPEEVGHGQHQPDRRRQPVSPPPPPRPISPPHTYGYISGPLVSDMDTDAPEEEEDEADMEVAKMQTRRLLLRGLEQTPASSVGDLESSVTGSMINGWGSASEEDNISSGRSSVSSSDGSFFTDADFAQAVAAAAEYAGLKVARRQMQDAAGRRHFHASQCPRPTSPVSTDSNVSAAVVQKARPAKKQKHQPGHLRREAYTDDLPPPPVPPPAIKSPTAQSKAQLEVRPVMVPKLPSIEARTDRSSDRKGGNYKGREVLDGRQVADMRPNPGDAREAQEQPNDGKGRGNKAAKRDLPPAKAHLIQEDILPYCRPTFPTSNNPRDPSSSSSMSSRGSGSRQREQANVGRRNIAEMQVLGGYEREDNNEELEETES", "length": 1653, "header": "tr|A0AAA9SYD9-1|F1N739_BOVIN Computationally mapped isoform of Roundabout guidance receptor 1 OS=Bos taurus OX=9913 GN=ROBO1 PE=3 SV=1 CANONICAL=F1N739-1" }, "locus": { "chromosome": "1", "start_pos": 27253329, "end_pos": 26118200, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000101606.1", "url": "https://www.ensembl.org/id/ENSBTAT00000101606.1" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000088348.1", "url": "https://www.ensembl.org/id/ENSBTAP00000088348.1" } ] } }, { "isoform_ac": "A0AAA9T3N6-1", "url": "https://www.uniprot.org/uniprotkb/A0AAA9T3N6/entry", "sequence": { "sequence": "MKWTHAPFLAIISLLSLSKSHLFLAQLIPDPEDVERGKDNGTPIPTSDNDDNSLGYTGSRLRQEDFPPRIVEHPSDLIVSKGEPATLNCKAEGRPTPTIEWYKGGERVETDKDDPRSHRMLLPSGSLFFLRIVHGRKSRPDEGVYVCVARNYLGEAVSHNASLEVAILRDDFRQNPSDVMVAVGEPAVMECQPPRGHPEPTISWKKDGSPLDDKDERITIRGGKLMITYTRKSDAGKYVCVGTNMVGERESEVAELTVLERPSFVKRPSNLAVTVDDSAEFKCEARGDPVPTVRWRKDDGELPKSRYEIRDDHTLKIRKVTAGDMGSYTCVAENMVGKAEASATLTVQEPPHFVVKPRDQVVALGRTVTFQCEATGNPQPAIFWRREGSQNLLFSYQPPQSSSRFSVSQTGDLTITNVQRSDVGYYICQTLNVAGSIITKAYLEVTDVIADRPPPVIRQGPVNQTVAVDGTLVLSCVATGSPVPTILWRKDGVLVSTQDSRIKQLETGVLQIRYAKLGDTGRYTCIASTPSGEATWSAYIEVQEFGVPVQPPRPTDPNLIPSAPSKPEVTDVSRNTVTLSWQPNLNSGATPTSYIIEAFSHASGSSWQTVAENVKTETFAIKGLKPNAIYLFLVRAANAYGISDPSQISDPVKTQDVPPTSQGVDHKQVQRELGNVVLHLHNPTILSSSSIEVHWTVDQQSQYIQGYKVLYRPSGANHGESEWLVFEVRTPTKNSVVIPDLKKGVNYEIKARPFFNEFQGADSEIKFAKTLEEAPSAPPQSVTVSKNDGNGTAILVSWQPPPEDTQNGMVQEYKVWCLGNETRYHINKTVDGSTFSVVIPSLVPGIRYSVEVAASTGAGSGVKSEPQFIQLDSHGNPVSPEDQVSLAQQISDVVKQPAFIAGIGAACWIILMVFSIWLYRHRKKRNGLASTYAGIRKVPSFTFTPTVTYQRGGEAVSSGGRPGLLNISEPATQPWLADTWPNTGNNHNDCSINCCTAGNGNSDSNLTTYSRPADCIANYNNQLDNKQTNLMLPESTVYGDVDLSNKINEMKTFNSPNLKDGRFVNPSGQPTPYATTQLIQSNLSNNMNNGSGDSGEKHWKPPGQQKQEVAPIQYNIMEQNKLNKDYRANDTIAPTIPYNQSYDQNTGGSYNSSDRGSSTSGSQGHKKGARTPKVPKQGGMNWADLLPPPPAHPPPHSNSEEYSISVDESYDQEMPCPVPPARMYLQQGELEEEEDERGPTPPVRGAASSPAAVSYSHQSTATLTPSPQEELQPMLQDCPEEVGHGQHQPDRRRQPVSPPPPPRPISPPHTYGYISGPLVSDMDTDAPEEEEDEADMEVAKMQTRRLLLRGLEQTPASSVGDLESSVTGSMINGWGSASEEDNISSGRSSVSSSDGSFFTDADFAQAVAAAAEYAGLKVARRQMQDAAGRRHFHASQCPRPTSPVSTDSNVSAAVVQKARPAKKQKHQPGHLRREAYTDDLPPPPVPPPAIKSPTAQSKAQLEVRPVMVPKLPSIEARTDRSSDRKGGNYKGREVLDGRQVADMRPNPGDAREAQEQPNDGKGRGNKAAKRDLPPAKAHLIQEDILPYCRPTFPTSNNPRDPSSSSSMSSRGSGSRQREQANVGRRNIAEMQVLGGYEREDNNEELEETES", "length": 1650, "header": "tr|A0AAA9T3N6-1|F1N739_BOVIN Computationally mapped isoform of Roundabout guidance receptor 1 OS=Bos taurus OX=9913 GN=ROBO1 PE=3 SV=1 CANONICAL=F1N739-1" }, "locus": { "chromosome": "1", "start_pos": 27253329, "end_pos": 26118200, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000095029.1", "url": "https://www.ensembl.org/id/ENSBTAT00000095029.1" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000092386.1", "url": "https://www.ensembl.org/id/ENSBTAP00000092386.1" } ] } }, { "isoform_ac": "F1N279-1", "url": "https://www.uniprot.org/uniprotkb/F1N279/entry", "sequence": { "sequence": "MKWTHAPFLAIISLLSLSKSHLFLAQLIPDPEDVERGKDNGTPIPTSDNDDNSLGYTGSRLRQEDFPPRIVEHPSDLIVSKGEPATLNCKAEGRPTPTIEWYKGGERVETDKDDPRSHRMLLPSGSLFFLRIVHGRKSRPDEGVYVCVARNYLGEAVSHNASLEVAILRDDFRQNPSDVMVAVGEPAVMECQPPRGHPEPTISWKKDGSPLDDKDERITIRGGKLMITYTRKSDAGKYVCVGTNMVGERESEVAELTVLERPSFVKRPSNLAVTVDDSAEFKCEARGDPVPTVRWRKDDGELPKSRYEIRDDHTLKIRKVTAGDMGSYTCVAENMVGKAEASATLTVQVGSEPPHFVVKPRDQVVALGRTVTFQCEATGNPQPAIFWRREGSQNLLFSYQPPQSSSRFSVSQTGDLTITNVQRSDVGYYICQTLNVAGSIITKAYLEVTDVIADRPPPVIRQGPVNQTVAVDGTLVLSCVATGSPVPTILWRKDGVLVSTQDSRIKQLETGVLQIRYAKLGDTGRYTCIASTPSGEATWSAYIEVQEFGVPVQPPRPTDPNLIPSAPSKPEVTDVSRNTVTLSWQPNLNSGATPTSYIIEAFSHASGSSWQTVAENVKTETFAIKGLKPNAIYLFLVRAANAYGISDPSQISDPVKTQDVPPTSQGVDHKQVQRELGNVVLHLHNPTILSSSSIEVHWTVDQQSQYIQGYKVLYRPSGANHGESEWLVFEVRTPTKNSVVIPDLKKGVNYEIKARPFFNEFQGADSEIKFAKTLEEAPSAPPQSVTVSKNDGNGTAILVSWQPPPEDTQNGMVQEYKVWCLGNETRYHINKTVDGSTFSVVIPSLVPGIRYSVEVAASTGAGSGVKSEPQFIQLDSHGNPVSPEDQVSLAQQISDVVKQPAFIAGIGAACWIILMVFSIWLYRHRKKRNGLASTYAGIRKVTYQRGGEAVSSGGRPGLLNISEPATQPWLADTWPNTGNNHNDCSINCCTAGNGNSDSNLTTYSRPADCIANYNNQLDNKQTNLMLPESTVYGDVDLSNKINEMKTFNSPNLKDGRFVNPSGQPTPYATTQLIQSNLSNNMNNGSGDSGEKHWKPPGQQKQEVAPIQYNIMEQNKLNKDYRANDTIAPTIPYNQSYDQNTGGSYNSSDRGSSTSGSQGHKKGARTPKVPKQGGMNWADLLPPPPAHPPPHSNSEEYSISVDESYDQEMPCPVPPARMYLQQGELEEEEDERGPTPPVRGAASSPAAVSYSHQSTATLTPSPQEELQPMLQDCPEEVGHGQHQPDRRRQPVSPPPPPRPISPPHTYGYISGPLVSDMDTDAPEEEEDEADMEVAKMQTRRLLLRGLEQTPASSVGDLESSVTGSMINGWGSASEEDNISSGRSSVSSSDGSFFTDADFAQAVAAAAEYAGLKVARRQMQDAAGRRHFHASQCPRPTSPVSTDSNVSAAVVQKARPAKKQKHQPGHLRREAYTDDLPPPPVPPPAIKSPTAQSKAQLEVRPVMVPKLPSIEARTDRSSDRKGGNYKGREVLDGRQVADMRPNPGDAREAQEQPNDGKGRGNKAAKRDLPPAKAHLIQEDILPYCRPTFPTSNNPRDPSSSSSMSSRGSGSRQREQANVGRRNIAEMQVLGGYEREDNNEELEETES", "length": 1644, "header": "tr|F1N279-1|F1N739_BOVIN Computationally mapped isoform of Roundabout guidance receptor 1 OS=Bos taurus OX=9913 GN=ROBO1 PE=3 SV=4 CANONICAL=F1N739-1" }, "locus": { "chromosome": "1", "start_pos": 27253329, "end_pos": 26118200, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000048615.5", "url": "https://www.ensembl.org/id/ENSBTAT00000048615.5" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000045620.5", "url": "https://www.ensembl.org/id/ENSBTAP00000045620.5" } ] } }, { "isoform_ac": "F1N739-1", "url": "https://www.uniprot.org/uniprotkb/F1N739/entry", "sequence": { "sequence": "MIAEPAHFYLFGLICLCSGSRLRQEDFPPRIVEHPSDLIVSKGEPATLNCKAEGRPTPTIEWYKGGERVETDKDDPRSHRMLLPSGSLFFLRIVHGRKSRPDEGVYVCVARNYLGEAVSHNASLEVAILRDDFRQNPSDVMVAVGEPAVMECQPPRGHPEPTISWKKDGSPLDDKDERITIRGGKLMITYTRKSDAGKYVCVGTNMVGERESEVAELTVLERPSFVKRPSNLAVTVDDSAEFKCEARGDPVPTVRWRKDDGELPKSRYEIRDDHTLKIRKVTAGDMGSYTCVAENMVGKAEASATLTVQVGSEPPHFVVKPRDQVVALGRTVTFQCEATGNPQPAIFWRREGSQNLLFSYQPPQSSSRFSVSQTGDLTITNVQRSDVGYYICQTLNVAGSIITKAYLEVTDVIADRPPPVIRQGPVNQTVAVDGTLVLSCVATGSPVPTILWRKDGVLVSTQDSRIKQLETGVLQIRYAKLGDTGRYTCIASTPSGEATWSAYIEVQEFGVPVQPPRPTDPNLIPSAPSKPEVTDVSRNTVTLSWQPNLNSGATPTSYIIEAFSHASGSSWQTVAENVKTETFAIKGLKPNAIYLFLVRAANAYGISDPSQISDPVKTQDVPPTSQGVDHKQVQRELGNVVLHLHNPTILSSSSIEVHWTVDQQSQYIQGYKVLYRPSGANHGESEWLVFEVRTPTKNSVVIPDLKKGVNYEIKARPFFNEFQGADSEIKFAKTLEEAPSAPPQSVTVSKNDGNGTAILVSWQPPPEDTQNGMVQEYKVWCLGNETRYHINKTVDGSTFSVVIPSLVPGIRYSVEVAASTGAGSGVKSEPQFIQLDSHGNPVSPEDQVSLAQQISDVVKQPAFIAGIGAACWIILMVFSIWLYRHRKKRNGLASTYAGIRKVPSFTFTPTVTYQRGGEAVSSGGRPGLLNISEPATQPWLADTWPNTGNNHNDCSINCCTAGNGNSDSNLTTYSRPADCIANYNNQLDNKQTNLMLPESTVYGDVDLSNKINEMKTFNSPNLKDGRFVNPSGQPTPYATTQLIQSNLSNNMNNGSGDSGEKHWKPPGQQKQEVAPIQYNIMEQNKLNKDYRANDTIAPTIPYNQSYDQNTGGSYNSSDRGSSTSGSQGHKKGARTPKVPKQGGMNWADLLPPPPAHPPPHSNSEEYSISVDESYDQEMPCPVPPARMYLQQGELEEEEDERGPTPPVRGAASSPAAVSYSHQSTATLTPSPQEELQPMLQDCPEEVGHGQHQPDRRRQPVSPPPPPRPISPPHTYGYISGPLVSDMDTDAPEEEEDEADMEVAKMQTRRLLLRGLEQTPASSVGDLESSVTGSMINGWGSASEEDNISSGRSSVSSSDGSFFTDADFAQAVAAAAEYAGLKVARRQMQDAAGRRHFHASQCPRPTSPVSTDSNVSAAVVQKARPAKKQKHQPGHLRREAYTDDLPPPPVPPPAIKSPTAQSKAQLEVRPVMVPKLPSIEARTDRSSDRKGGNYKGREVLDGRQVADMRPNPGDAREAQEQPNDGKGRGNKAAKRDLPPAKAHLIQEDILPYCRPTFPTSNNPRDPSSSSSMSSRGSGSRQREQANVGRRNIAEMQVLGGYEREDNNEELEETES", "length": 1614, "header": "tr|F1N739-1|F1N739_BOVIN Isoform 1 of Roundabout guidance receptor 1 OS=Bos taurus OX=9913 GN=ROBO1 PE=3 SV=4 CANONICAL=F1N739-1" }, "locus": { "chromosome": "1", "start_pos": 26583152, "end_pos": 26118200, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000061264.4", "url": "https://www.ensembl.org/id/ENSBTAT00000061264.4" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000053683.4", "url": "https://www.ensembl.org/id/ENSBTAP00000053683.4" } ] } } ], "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "other", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 1204, "start_aa": "Thr", "end_pos": 1204, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr1204", "evidence": [ { "id": "", "database": "GlyGen", "url": "https://data.glygen.org/" } ], "filter_code": "000000000000000010000.00000000001000.0.01000" }, { "glytoucan_ac": "", "type": "O-linked", "subtype": "other", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 519, "start_aa": "Thr", "end_pos": 519, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr519", "evidence": [ { "id": "", "database": "GlyGen", "url": "https://data.glygen.org/" } ], "filter_code": "000000000000000010000.00000000001000.0.01000" } ], "phosphorylation": [], "glycation": [], "keywords": [ "glycoprotein", "glycoprotein_predicted" ], "publication": [], "pathway": [ { "id": "bta:536815", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?bta:536815", "resource": "KEGG Pathway" }, { "id": "R-BTA-376176", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-BTA-376176", "resource": "Reactome", "description": "Signaling by ROBO receptors" }, { "id": "R-BTA-428890", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-BTA-428890", "resource": "Reactome", "description": "Role of ABL in ROBO-SLIT signaling" }, { "id": "R-BTA-8985586", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-BTA-8985586", "resource": "Reactome", "description": "SLIT2:ROBO1 increases RHOA activity" }, { "id": "R-BTA-9010553", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-BTA-9010553", "resource": "Reactome", "description": "Regulation of expression of SLITs and ROBOs" } ], "orthologs": [], "go_annotation": { "categories": [ { "name": "Biological Process", "total": 18, "go_terms": [ { "name": "chemotaxis", "id": "GO:0006935", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006935", "evidence": [ { "database": "UniProtKB", "id": "F1N739", "url": "https://www.uniprot.org/uniprotkb/F1N739" } ], "pmid": "" }, { "name": "axon midline choice point recognition", "id": "GO:0016199", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016199", "evidence": [ { "database": "UniProtKB", "id": "F1N739", "url": "https://www.uniprot.org/uniprotkb/F1N739" } ], "pmid": "" }, { "name": "central nervous system development", "id": "GO:0007417", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007417", "evidence": [ { "database": "UniProtKB", "id": "F1N739", "url": "https://www.uniprot.org/uniprotkb/F1N739" } ], "pmid": "" }, { "name": "Roundabout signaling pathway", "id": "GO:0035385", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0035385", "evidence": [ { "database": "UniProtKB", "id": "F1N739", "url": "https://www.uniprot.org/uniprotkb/F1N739" } ], "pmid": "" }, { "name": "regulation of multicellular organismal process", "id": "GO:0051239", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0051239", "evidence": [ { "database": "UniProtKB", "id": "F1N739", "url": "https://www.uniprot.org/uniprotkb/F1N739" } ], "pmid": "" }, { "name": "regulation of anatomical structure morphogenesis", "id": "GO:0022603", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0022603", "evidence": [ { "database": "UniProtKB", "id": "F1N739", "url": "https://www.uniprot.org/uniprotkb/F1N739" } ], "pmid": "" }, { "name": "negative regulation of chemokine-mediated signaling pathway", "id": "GO:0070100", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0070100", "evidence": [ { "database": "UniProtKB", "id": "F1N739", "url": "https://www.uniprot.org/uniprotkb/F1N739" } ], "pmid": "" }, { "name": "positive regulation of MAPK cascade", "id": "GO:0043410", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0043410", "evidence": [ { "database": "UniProtKB", "id": "F1N739", "url": "https://www.uniprot.org/uniprotkb/F1N739" } ], "pmid": "" }, { "name": "negative regulation of cell migration", "id": "GO:0030336", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030336", "evidence": [ { "database": "UniProtKB", "id": "F1N739", "url": "https://www.uniprot.org/uniprotkb/F1N739" } ], "pmid": "" }, { "name": "positive regulation of Rho protein signal transduction", "id": "GO:0035025", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0035025", "evidence": [ { "database": "UniProtKB", "id": "F1N739", "url": "https://www.uniprot.org/uniprotkb/F1N739" } ], "pmid": "" }, { "name": "homophilic cell adhesion via plasma membrane adhesion molecules", "id": "GO:0007156", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007156", "evidence": [ { "database": "UniProtKB", "id": "F1N739", "url": "https://www.uniprot.org/uniprotkb/F1N739" } ], "pmid": "" }, { "name": "positive regulation of axonogenesis", "id": "GO:0050772", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0050772", "evidence": [ { "database": "UniProtKB", "id": "F1N739", "url": "https://www.uniprot.org/uniprotkb/F1N739" } ], "pmid": "" }, { "name": "positive regulation of vascular endothelial growth factor receptor signaling pathway", "id": "GO:0030949", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030949", "evidence": [ { "database": "UniProtKB", "id": "F1N739", "url": "https://www.uniprot.org/uniprotkb/F1N739" } ], "pmid": "" }, { "name": "chemorepulsion involved in postnatal olfactory bulb interneuron migration", "id": "GO:0021836", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0021836", "evidence": [ { "database": "UniProtKB", "id": "F1N739", "url": "https://www.uniprot.org/uniprotkb/F1N739" } ], "pmid": "" }, { "name": "negative regulation of negative chemotaxis", "id": "GO:0050925", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0050925", "evidence": [ { "database": "UniProtKB", "id": "F1N739", "url": "https://www.uniprot.org/uniprotkb/F1N739" } ], "pmid": "" }, { "name": "cell migration involved in sprouting angiogenesis", "id": "GO:0002042", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0002042", "evidence": [ { "database": "UniProtKB", "id": "F1N739", "url": "https://www.uniprot.org/uniprotkb/F1N739" } ], "pmid": "" }, { "name": "positive regulation of vascular endothelial growth factor signaling pathway", "id": "GO:1900748", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:1900748", "evidence": [ { "database": "UniProtKB", "id": "F1N739", "url": "https://www.uniprot.org/uniprotkb/F1N739" } ], "pmid": "" }, { "name": "negative regulation of mammary gland epithelial cell proliferation", "id": "GO:0033600", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0033600", "evidence": [ { "database": "UniProtKB", "id": "F1N739", "url": "https://www.uniprot.org/uniprotkb/F1N739" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 4, "go_terms": [ { "name": "membrane", "id": "GO:0016020", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016020", "evidence": [ { "database": "UniProtKB", "id": "F1N739", "url": "https://www.uniprot.org/uniprotkb/F1N739" } ], "pmid": "" }, { "name": "cytoplasm", "id": "GO:0005737", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005737", "evidence": [ { "database": "UniProtKB", "id": "F1N739", "url": "https://www.uniprot.org/uniprotkb/F1N739" } ], "pmid": "" }, { "name": "plasma membrane", "id": "GO:0005886", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005886", "evidence": [ { "database": "UniProtKB", "id": "F1N739", "url": "https://www.uniprot.org/uniprotkb/F1N739" } ], "pmid": "" }, { "name": "cell surface", "id": "GO:0009986", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0009986", "evidence": [ { "database": "UniProtKB", "id": "F1N739", "url": "https://www.uniprot.org/uniprotkb/F1N739" } ], "pmid": "" } ] }, { "name": "Molecular Function", "total": 3, "go_terms": [ { "name": "axon guidance receptor activity", "id": "GO:0008046", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008046", "evidence": [ { "database": "UniProtKB", "id": "F1N739", "url": "https://www.uniprot.org/uniprotkb/F1N739" } ], "pmid": "" }, { "name": "identical protein binding", "id": 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}, "isoforms": [ { "isoform_ac": "A0A3Q1LRZ1-1", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1LRZ1/entry", "sequence": { "sequence": "MRRPGAPASWIWWRMLRQVLRRGLQSFCHRLGLCVSRHPVFFLTVPAVLTITFGLSALNRFQPEGDLERLVAPSHSLAKIERSLASSLFPLDQSKSQLYSDLHTPGRYGRVILLSPPGDNILLQAEGILQTHRAVLEMKVNYKGYNYTFSHLCVLRNQDKKCVLDDIISVLEDLRQAAVSNKTTARVQVRYPNTKLKDGRNSFIGHQLGGVVEVPNSKDQRVKSARAIQITYYLQTYGSATQDLIGEKWENEFCKLMRKLQEEHQDLQLYSLASFSLWRDFHKSSILARSKVLVSLMLILTTATLSSSMKDCLRGKPFLGLLGVLTVCISIITAAGIFFITDGKYNSTLLGIPFFAMGISTAFILGQ", "length": 367, "header": "tr|A0A3Q1LRZ1-1|F6PVM2_BOVIN Computationally mapped isoform of Patched domain containing 4 OS=Bos taurus OX=9913 GN=PTCHD4 PE=3 SV=1 CANONICAL=F6PVM2-1" }, "locus": { "chromosome": "23", "start_pos": 21094310, "end_pos": 20919398, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000078691.3", "url": "https://www.ensembl.org/id/ENSBTAT00000078691.3" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000057842.2", "url": "https://www.ensembl.org/id/ENSBTAP00000057842.2" } ] } }, { "isoform_ac": "F6PVM2-1", "url": "https://www.uniprot.org/uniprotkb/F6PVM2/entry", "sequence": { "sequence": 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"ENSBTAG00000016729", "url": "https://bgee.org/?page=gene&gene_id=ENSBTAG00000016729", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "781505", "url": "https://www.ncbi.nlm.nih.gov/gene/781505", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR003148", "url": "https://www.ebi.ac.uk/interpro/entry/IPR003148", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR003929", "url": "https://www.ebi.ac.uk/interpro/entry/IPR003929", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR013099", "url": "https://www.ebi.ac.uk/interpro/entry/IPR013099", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR036291", "url": "https://www.ebi.ac.uk/interpro/entry/IPR036291", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR047871", "url": "https://www.ebi.ac.uk/interpro/entry/IPR047871", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "bta:781505", "url": "https://www.genome.jp/dbget-bin/www_bget?bta:781505", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "F1N4T0", "url": "https://www.orthodb.org/?gene=F1N4T0", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR10027", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR10027", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR10027:SF9", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR10027:SF9", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF03493", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF03493", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF07885", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF07885", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF22614", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF22614", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "XP_024832437", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_024832437", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "29463", "url": "https://www.rhea-db.org/rhea/29463", "database": "Rhea", "categories": [ "Enzyme and Pathway" ] }, { "id": "A0A3Q1LLN8", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1LLN8", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A3Q1LLN8-1", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1LLN8-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A3Q1LU48", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1LU48", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A3Q1LU48-1", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1LU48-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0AAA9SPI3", "url": "https://www.uniprot.org/uniprotkb/A0AAA9SPI3", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0AAA9SPI3-1", "url": "https://www.uniprot.org/uniprotkb/A0AAA9SPI3-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0AAA9TI47", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TI47", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0AAA9TI47-1", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TI47-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "F1N4T0", "url": "https://www.uniprot.org/uniprotkb/F1N4T0", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "F1N4T0-1", "url": "https://www.uniprot.org/uniprotkb/F1N4T0-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MVDLESEVPPLPPRYRFRDLLLGDQGWQNDDRVQVEFYMNENTFKERLKLFFIKNQRSSLRIRLFNFSLKLLSCLLYIIRVLLENPSQGNEWSHIFWVNRSLPLWGLQVLVALISLFETILLGYLSYKGNIWEQILRIPFILEIINAVPFIISIFWPSLRNLFVPVFLNCWLAKHALENMINDLHRAIQRTQSAMFNQVLILISTLLCLIFTCICGIQHLERIGKKLNLFDSLYFCIVTFSTVGFGDVTPETWSSKLFVVAMICVALVVLPIQFEQLAYLWMERQKSGGNYSRHRAQTEKHVVLCVSSLKIDLLMDFLNEFYAHPRLQDYYVVILCPTEMDVQVRRILQIPMWSQRVIYLQGSALKDQDLLRAKMDDAEACFILSSRCEVDRTSSDHQTILRAWAVKDFAPNCPLYVQILKPENKFHIKFADHVVCEEEFKYAMLALNCICPATSTLITLLVHTSRGQEGQQSPEQWQKMYGRCSGNEVYHIVLEESTFFAEYEGKSFTYASFHAHKKFGVCLIGIRREDNKNILLNPGPRYIMNATDTCFYINITKEENSAFKNHDHQKKSNVPRSFYHGPSRLPVHSIIASMGTVAIDLQDTSCRSASGPTLSLPTEGSKEVRRPSIAPVLEVADTSSIQTCDLLSDQSEDETTPDEEMSSNLEYAKGYPPYSPYIGSSPTFCHLLHEKVPFCCLRLDKSCQHNYYEDAKAYGFKNKLIIVAAETAGNGLYNFIVPLRAYYRPKKELNPVILLLDNPPDMHFLDAICWFPMVYYMVGSIDNLDDLLRCGVTFAANMVVVDKESTMSAEEDYMADAKTIVNVQTLFRLFSSLSIITELTHPANMRFMQFRAKDCYSLALSKLEKKERERGSNLAFIFRLPFAAGRVFSISMLDTLLYQSFVKDYMISITRLLLGLDTTPGSGFLCSMKITEDDLWIRTYARLYQKLCSSTGDVPIGIYRTESQKLTTSESQISISVEEWEDTKDAKEQGHHRSNHRNSTSSDQSDHPLLRRKSMQWARRLSRKGPKHSGRTAEKMTQQRLNLYRRSERQELAELVKNRMKHLGLSTVGYDEMNDHQNTLSYILINPSPDTRLELNDVVYLIRPDPLAYLPNSEPSRKNSICNTMVQDSREETQL", "length": 1135, "header": "tr|F1N4T0-1|F1N4T0_BOVIN Isoform 1 of Potassium sodium-activated channel subfamily T member 2 OS=Bos taurus OX=9913 GN=KCNT2 PE=4 SV=3 CANONICAL=F1N4T0-1" }, "isoforms": [ { "isoform_ac": "A0A3Q1LLN8-1", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1LLN8/entry", "sequence": { "sequence": "MSPQLVPCGSTFVPFPRLQSSISDSRERVQVEFYMNENTFKERLKLFFIKNQRSSLRIRLFNFSLKLLSCLLYIIRVLLENPSQGNEWSHIFWVNRSLPLWGLQVLVALISLFETILLGYLSYKGNIWEQILRIPFILEIINAVPFIISIFWPSLRNLFVPVFLNCWLAKHALENMINDLHRAIQRTQSAMFNQVLILISTLLCLIFTCICGIQHLERIGKKLNLFDSLYFCIVTFSTVGFGDVTPETWSSKLFVVAMICVALVVLPIQFEQLAYLWMERQKSGGNYSRHRAQTEKHVVLCVSSLKIDLLMDFLNEFYAHPRLQDYYVVILCPTEMDVQVRRILQIPMWSQRVIYLQGSALKDQDLLRAKMDDAEACFILSSRCEVDRTSSDHQTILRAWAVKDFAPNCPLYVQILKPENKFHIKFADHVVCEEEFKYAMLALNCICPATSTLITLLVHTSRGQEGQQSPEQWQKMYGRCSGNEVYHIVLEESTFFAEYEGKSFTYASFHAHKKFGVCLIGIRREDNKNILLNPGPRYIMNATDTCFYINITKEENSAFKNHDHQKKSNVPRSFYHGPSRLPVHSIIASMGTVAIDLQDTSCRSASGPTLSLPTEGSKEVRRPSIAPVLEVADTSSIQTCDLLSDQSEDETTPDEEMSSNLEYAKGYPPYSPYIGSSPTFCHLLHEKVPFCCLRLDKSCQHNYYEDAKAYGFKNKLIIVAAETAGNGLYNFIVPLRAYYRPKKELNPVILLLDNPLDDLLRCGVTFAANMVVVDKESTMSAEEDYMADAKTIVNVQTLFRLFSSLSIITELTHPANMRFMQFRAKDCYSLALSKLEKKERERGSNLAFIFRLPFAAGRVFSISMLDTLLYQSFVKDYMISITRLLLGLDTTPGSGFLCSMKITEDDLWIRTYARLYQKLCSSTGDVPIGIYRTESQKLTTSESQISISVEEWEDTKDAKEQGHHRSNHRNSTSSDQSDHPLLRRKSMQWARRLSRKGPKHSGRTAEKMTQQRLNLYRRSERQELAELVKNRMKHLGLSTVGYDEMNDHQNTLSYILINPSPDTRLELNDVVYLIRPDPLAYLPNSEPSRKNSICNTMVQDSREETQL", "length": 1107, "header": "tr|A0A3Q1LLN8-1|A0A3Q1LLN8_BOVIN Computationally mapped isoform of Potassium sodium-activated channel subfamily T member 2 OS=Bos taurus OX=9913 GN=KCNT2 PE=4 SV=2 CANONICAL=F1N4T0-1" }, "locus": { "chromosome": "16", "start_pos": 6826460, "end_pos": 6495335, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000083315.2", "url": "https://www.ensembl.org/id/ENSBTAT00000083315.2" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000057506.2", "url": "https://www.ensembl.org/id/ENSBTAP00000057506.2" } ] } }, { "isoform_ac": "A0A3Q1LU48-1", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1LU48/entry", "sequence": { "sequence": "MVDLESEVPPLPPRYRFRDLLLGDQGWQNDDRVQVEFYMNENTFKERLKLFFIKNQRSSLRIRLFNFSLKLLSCLLYIIRVLLENPSQGNEWSHIFWVNRSLPLWGLQVLVALISLFETILLGYLSYKGNIWEQILRIPFILEIINAVPFIISIFWPSLRNLFVPVFLNCWLAKHALENMINDLHRAIQRTQSAMFNQVLILISTLLCLIFTCICGIQHLERIGKKLNLFDSLYFCIVTFSTVGFGDVTPETWSSKLFVVAMICVALVVLPIQFEQLAYLWMERQKSGGNYSRHRAQTEKHVVLCVSSLKIDLLMDFLNEFYAHPRLQDYYVVILCPTEMDVQVRRILQIPMWSQRVIYLQGSALKDQDLLRAKMDDAEACFILSSRCEVDRTSSDHQTILRAWAVKDFAPNCPLYVQILKPENKFHIKFADHVVCEEEFKYAMLALNCICPATSTLITLLVHTSRGQEGQQSPEQWQKMYGRCSGNEVYHIVLEESTFFAEYEGKSFTYASFHAHKKFGVCLIGIRREDNKNILLNPGPRYIMNATDTCFYINITKEENSAFKNHDHQKKSNVPRSFYHGPSRLPVHSIIASMGTVAIDLQDTSCRSASGPTLSLPTEGSKEVRRPSIAPVLEVADTSSIQTCDLLSDQSEDETTPDEEMSSNLEYAKGYPPYSPYIGSSPTFCHLLHEKVPFCCLRLDKSCQHNYYEDAKAYGFKNKLIIVAAETAGNGLYNFIVPLRAYYRPKKELNPVILLLDNPLDDLLRCGVTFAANMVVVDKESTMSAEEDYMADAKTIVNVQTLFRLFSSLSIITELTHPANMRFMQFRAKDCYSLALSKLEKKERERGSNLAFIFRLPFAAGRVFSISMLDTLLYQSFVKDYMISITRLLLGLDTTPGSGFLCSMKITEDDLWIRTYARLYQKLCSSTGDVPIGIYRTESQKLTTSESQISISVEEWEDTKDAKEQGHHRSNHRNSTSSDQSDHPLLRRKSMQWARRLSRKGPKHSGRTAEKMTQQRLNLYRRSERQELAELVKNRMKHLGLSTVGYVSCDPETQSLQKL", "length": 1059, "header": "tr|A0A3Q1LU48-1|F1N4T0_BOVIN Computationally mapped isoform of Potassium sodium-activated channel subfamily T member 2 OS=Bos taurus OX=9913 GN=KCNT2 PE=4 SV=2 CANONICAL=F1N4T0-1" }, "locus": { "chromosome": "16", "start_pos": 6802606, "end_pos": 6388680, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000076009.2", "url": "https://www.ensembl.org/id/ENSBTAT00000076009.2" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000064029.2", "url": "https://www.ensembl.org/id/ENSBTAP00000064029.2" } ] } }, { "isoform_ac": "A0AAA9SPI3-1", "url": "https://www.uniprot.org/uniprotkb/A0AAA9SPI3/entry", "sequence": { "sequence": "MSPQLVPCGSTFVPFPRLQSSISDSRERVQVEFYMNENTFKERLKLFFIKNQRSSLRIRLFNFSLKLLSCLLYIIRVLLENPSQGNEWSHIFWVNRSLPLWGLQVLVALISLFETILLGYLSYKGNIWEQILRIPFILEIINAVPFIISIFWPSLRNLFVPVFLNCWLAKHALENMINDLHRAIQRTQSAMFNQVLILISTLLCLIFTCICGIQHLERIGKKLNLFDSLYFCIVTFSTVGFGDVTPETWSSKLFVVAMICVALVVLPIQFEQLAYLWMERQKSGGNYSRHRAQTEKHVVLCVSSLKIDLLMDFLNEFYAHPRLQDYYVVILCPTEMDVQVRRILQIPMWSQRVIYLQGSALKDQDLLRAKMDDAEACFILSSRCEVDRTSSDHQTILRAWAVKDFAPNCPLYVQILKPENKFHIKFADHVVCEEEFKYAMLALNCICPATSTLITLLVHTSRGQEGQQSPEQWQKMYGRCSGNEVYHIVLEESTFFAEYEGKSFTYASFHAHKKFGVCLIGIRREDNKNILLNPGPRYIMNATDTCFYINITKEENSAFKNHDHQKKSNVPRSFYHGPSRLPVHSIIASMGTVAIDLQDTSCRSASGPTLSLPTEGSKEVRRPSIAPVLEVADTSSIQTCDLLSDQSEDETTPDEEMSSNLEYAKGYPPYSPYIGSSPTFCHLLHEKVPFCCLRLDKSCQHNYYEDAKAYGFKNKLIIVAAETAGNGLYNFIVPLRAYYRPKKELNPVILLLDNPLDDLLRCGVTFAANMVVVDKESTMSAEEDYMADAKTIVNVQTLFRLFSSLSIITELTHPANMRFMQFRAKDCYSLALSKLEKKERERGSNLAFIFRLPFAAGRVFSISMLDTLLYQSFVKDYMISITRLLLGLDTTPGSGFLCSMKITEDDLWIRTYARLYQKLCSSTGDVPIGIYRTESQKLTTSECREIASQSQISISVEEWEDTKDAKEQGHHRSNHRNSTSSDQSDHPLLRRKSMQWARRLSRKGPKHSGRTAEKMTQQRLNLYRRSERQELAELVKNRMKHLGLSTVGYDEMNDHQNTLSYILINPSPDTRLELNDVVYLIRPDPLAYLPNSEPSRKNSICNTMVQDSREETQL", "length": 1114, "header": "tr|A0AAA9SPI3-1|F1N4T0_BOVIN Computationally mapped isoform of Potassium sodium-activated channel subfamily T member 2 OS=Bos taurus OX=9913 GN=KCNT2 PE=4 SV=1 CANONICAL=F1N4T0-1" }, "locus": { "chromosome": "16", "start_pos": 6826460, "end_pos": 6495335, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000103604.1", "url": "https://www.ensembl.org/id/ENSBTAT00000103604.1" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000085840.1", "url": "https://www.ensembl.org/id/ENSBTAP00000085840.1" } ] } }, { "isoform_ac": "A0AAA9TI47-1", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TI47/entry", "sequence": { "sequence": "MVDLESEVPPLPPRYRFRDLLLGDQGWQNDDRVQVEFYMNENTFKERLKLFFIKNQRSSLRIRLFNFSLKLLSCLLYIIRVLLENPSQGNEWSHIFWVNRSLPLWGLQVLVALISLFETILLGYLSYKGNIWEQILRIPFILEIINAVPFIISIFWPSLRNLFVPVFLNCWLAKHALENMINDLHRAIQRTQSAMFNQVLILISTLLCLIFTCICGIQHLERIGKKLNLFDSLYFCIVTFSTVGFGDVTPETWSSKLFVVAMICVALVVLPIQFEQLAYLWMERQKSGGNYSRHRAQTEKHVVLCVSSLKIDLLMDFLNEFYAHPRLQDYYVVILCPTEMDVQVRRILQIPMWSQRVIYLQGSALKDQDLLRAKMDDAEACFILSSRCEVDRTSSDHQTILRAWAVKDFAPNCPLYVQILKPENKFHIKFADHVVCEEEFKYAMLALNCICPATSTLITLLVHTSRGQFGVCLIGIRREDNKNILLNPGPRYIMNATDTCFYINITKEENSAFKNHDHQKKSNVPRSFYHGPSRLPVHSIIASMGTVAIDLQDTSCRSASGPTLSLPTEGSKEVRRPSIAPVLEVADTSSIQTCDLLSDQSEDETTPDEEMSSNLEYAKGYPPYSPYIGSSPTFCHLLHEKVPFCCLRLDKSCQHNYYEDAKAYGFKNKLIIVAAETAGNGLYNFIVPLRAYYRPKKELNPVILLLDNPLDDLLRCGVTFAANMVVVDKESTMSAEEDYMADAKTIVNVQTLFRLFSSLSIITELTHPANMRFMQFRAKDCYSLALSKLEKKERERGSNLAFIFRLPFAAGRVFSISMLDTLLYQSFVKDYMISITRLLLGLDTTPGSGFLCSMKITEDDLWIRTYARLYQKLCSSTGDVPIGIYRTESQKLTTSECREIASQSQISISVEEWEDTKDAKEQGHHRSNHRNSTSSDQSDHPLLRRKSMQWARRLSRKGPKHSGRTAEKMTQQRLNLYRRSERQELAELVKNRMKHLGLSTVGYDEMNDHQNTLSYILINPSPDTRLELNDVVYLIRPDPLAYLPNSEPSRKNSICNTMVQDSREETQL", "length": 1068, "header": "tr|A0AAA9TI47-1|F1N4T0_BOVIN Computationally mapped isoform of Potassium sodium-activated channel subfamily T member 2 OS=Bos taurus OX=9913 GN=KCNT2 PE=4 SV=1 CANONICAL=F1N4T0-1" }, "locus": { "chromosome": "16", "start_pos": 6826460, "end_pos": 6388680, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000135273.1", "url": "https://www.ensembl.org/id/ENSBTAT00000135273.1" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000097955.1", "url": "https://www.ensembl.org/id/ENSBTAP00000097955.1" } ] } }, { "isoform_ac": "F1N4T0-1", "url": "https://www.uniprot.org/uniprotkb/F1N4T0/entry", "sequence": { "sequence": "MVDLESEVPPLPPRYRFRDLLLGDQGWQNDDRVQVEFYMNENTFKERLKLFFIKNQRSSLRIRLFNFSLKLLSCLLYIIRVLLENPSQGNEWSHIFWVNRSLPLWGLQVLVALISLFETILLGYLSYKGNIWEQILRIPFILEIINAVPFIISIFWPSLRNLFVPVFLNCWLAKHALENMINDLHRAIQRTQSAMFNQVLILISTLLCLIFTCICGIQHLERIGKKLNLFDSLYFCIVTFSTVGFGDVTPETWSSKLFVVAMICVALVVLPIQFEQLAYLWMERQKSGGNYSRHRAQTEKHVVLCVSSLKIDLLMDFLNEFYAHPRLQDYYVVILCPTEMDVQVRRILQIPMWSQRVIYLQGSALKDQDLLRAKMDDAEACFILSSRCEVDRTSSDHQTILRAWAVKDFAPNCPLYVQILKPENKFHIKFADHVVCEEEFKYAMLALNCICPATSTLITLLVHTSRGQEGQQSPEQWQKMYGRCSGNEVYHIVLEESTFFAEYEGKSFTYASFHAHKKFGVCLIGIRREDNKNILLNPGPRYIMNATDTCFYINITKEENSAFKNHDHQKKSNVPRSFYHGPSRLPVHSIIASMGTVAIDLQDTSCRSASGPTLSLPTEGSKEVRRPSIAPVLEVADTSSIQTCDLLSDQSEDETTPDEEMSSNLEYAKGYPPYSPYIGSSPTFCHLLHEKVPFCCLRLDKSCQHNYYEDAKAYGFKNKLIIVAAETAGNGLYNFIVPLRAYYRPKKELNPVILLLDNPPDMHFLDAICWFPMVYYMVGSIDNLDDLLRCGVTFAANMVVVDKESTMSAEEDYMADAKTIVNVQTLFRLFSSLSIITELTHPANMRFMQFRAKDCYSLALSKLEKKERERGSNLAFIFRLPFAAGRVFSISMLDTLLYQSFVKDYMISITRLLLGLDTTPGSGFLCSMKITEDDLWIRTYARLYQKLCSSTGDVPIGIYRTESQKLTTSESQISISVEEWEDTKDAKEQGHHRSNHRNSTSSDQSDHPLLRRKSMQWARRLSRKGPKHSGRTAEKMTQQRLNLYRRSERQELAELVKNRMKHLGLSTVGYDEMNDHQNTLSYILINPSPDTRLELNDVVYLIRPDPLAYLPNSEPSRKNSICNTMVQDSREETQL", "length": 1135, "header": "tr|F1N4T0-1|F1N4T0_BOVIN Isoform 1 of Potassium sodium-activated channel subfamily T member 2 OS=Bos taurus OX=9913 GN=KCNT2 PE=4 SV=3 CANONICAL=F1N4T0-1" }, "locus": { "chromosome": "16", "start_pos": 6826460, "end_pos": 6388680, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000048534.5", "url": "https://www.ensembl.org/id/ENSBTAT00000048534.5" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000045553.4", "url": "https://www.ensembl.org/id/ENSBTAP00000045553.4" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [ { "id": "bta:781505", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?bta:781505", "resource": "KEGG Pathway" } ], "orthologs": [], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 1, "go_terms": [ { "name": "plasma membrane", "id": "GO:0005886", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005886", "evidence": [ { "database": "UniProtKB", "id": "F1N4T0", "url": "https://www.uniprot.org/uniprotkb/F1N4T0" } ], "pmid": "" } ] }, { "name": "Molecular Function", "total": 3, "go_terms": [ { "name": "potassium channel activity", "id": "GO:0005267", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005267", "evidence": [ { "database": "UniProtKB", "id": "F1N4T0", "url": "https://www.uniprot.org/uniprotkb/F1N4T0" } ], "pmid": "" }, { "name": "outward rectifier potassium channel activity", "id": "GO:0015271", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0015271", "evidence": [ { "database": "UniProtKB", "id": "F1N4T0", "url": "https://www.uniprot.org/uniprotkb/F1N4T0" } ], "pmid": "" }, { "name": "intracellular sodium-activated potassium channel activity", "id": "GO:0005228", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005228", "evidence": [ { "database": "UniProtKB", "id": "F1N4T0", "url": "https://www.uniprot.org/uniprotkb/F1N4T0" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 1, "go_terms": [ { "name": "potassium ion transmembrane transport", "id": "GO:0071805", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0071805", "evidence": [ { "database": "UniProtKB", "id": "F1N4T0", "url": "https://www.uniprot.org/uniprotkb/F1N4T0" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 290, "end_pos": 292, "annotation": "n_glycosylation_sequon" }, { "start_pos": 545, "end_pos": 547, "annotation": "n_glycosylation_sequon" }, { "start_pos": 554, "end_pos": 556, "annotation": "n_glycosylation_sequon" }, { "start_pos": 66, "end_pos": 68, "annotation": "n_glycosylation_sequon" }, { "start_pos": 998, "end_pos": 1000, "annotation": "n_glycosylation_sequon" }, { "start_pos": 99, "end_pos": 101, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [ { "id": "29463", "name": "", "equation": "K(+)(in) = K(+)(out)", "summary": "", "cellular_location": "", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [ "P35526-1" ], "evidence": [ { "id": "29463", "database": "Rhea", "url": "https://www.rhea-db.org/rhea/29463" } ] } ], "reaction_participants": [], "reaction_enzymes": [ { "uniprot_ac": "P35526", "gene_name": "CLIC5", "activity": [ { "ec_number": "1.8.-.-", "activity": "", "evidence": [ { "id": "P35526", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P35526" } ] } ] } ], "biomarkers": [], "structures": [ { "pdb_id": "AF-F1N4T0-F1", "pdb_chain": "global", "start_pos": 1, "end_pos": 1135, "overlap": "1.0", "method": "AlphaFold", "type": "alphafold", "resolution": -1.0, "url": "https://data.glygen.org/ln2downloads/pdb/current/AF-F1N4T0-F1.pdb", "url_external": "https://alphafold.ebi.ac.uk/entry/F1N4T0" } ], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "F1N4T0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1N4T0" }, { "id": "PS51201", "database": "PROSITE", "url": 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"mass": { "chemical_mass": 47464.0, "monoisotopic_mass": 47464.0 }, "refseq": { "ac": "NP_001179193", "name": "TRAF family member-associated NF-kappa-B activator", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001179193" }, "gene_names": [ { "name": "TANK", "type": "recommended", "evidence": [ { "id": "F6R2Z7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F6R2Z7" } ] }, { "name": "TANK", "type": "synonym", "evidence": [ { "id": "NP_001179193", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001179193" } ] } ], "protein_names": [ { "name": "TRAF family member associated NFKB activator", "type": "synonym", "evidence": [ { "id": "F6R2Z7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F6R2Z7/entry#names_and_taxonomy" } ] }, { "name": "TRAF family member-associated NF-kappa-B activator", "type": "synonym", "evidence": [ { "id": "NP_001179193", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001179193" } ] } ], "function": [], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Bos taurus", "taxid": 9913, "evidence": [ { "database": "UniProtKB", "id": "F6R2Z7", "url": "https://www.uniprot.org/uniprotkb/F6R2Z7" } ], "common_name": "Bovine", "glygen_name": "Bovine", "reference_species": "Bos taurus [9913]" } ], "gene": [ { "name": "TANK", "url": "https://www.uniprot.org/uniprotkb/F6R2Z7", "locus": { "chromosome": "2", "start_pos": 35143374, "end_pos": 35239417, "strand": "+", "evidence": [ { "database": "Ensembl Gene", "id": "ENSBTAG00000006654", "url": "https://www.ensembl.org/id/ENSBTAG00000006654" } ] } } ], "crossref": [ { "id": "F6R2Z7", "url": "https://alphafold.ebi.ac.uk/entry/F6R2Z7", "database": "AlphaFoldDB", "categories": [] }, { "id": "ENSBTAG00000006654", "url": "https://bgee.org/?page=gene&gene_id=ENSBTAG00000006654", "database": "Bgee", "categories": [ 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"Protein Classification" ] }, { "id": "F6R2Z7", "url": "https://www.orthodb.org/?gene=F6R2Z7", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR15249", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR15249", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR15249:SF0", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR15249:SF0", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF12845", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF12845", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "R-BTA-936964", "url": "https://www.reactome.org/PathwayBrowser/#R-BTA-936964", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "R-BTA-9824878", "url": "https://www.reactome.org/PathwayBrowser/#R-BTA-9824878", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "NP_001179193", "url": 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"database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0AAA9TT66-1", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TT66-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "F6R2Z7", "url": "https://www.uniprot.org/uniprotkb/F6R2Z7", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "F6R2Z7-1", "url": "https://www.uniprot.org/uniprotkb/F6R2Z7-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MDKNIGEQLNKAYEAFRQACMDRDSAVKELQQKTENYEQRIREQQEQLSLQQTIIDKLTSQLLLVNSSRDNSCGYVPLLEDSEARKNNLTLDQPHDKAKSGIPREKESKVRRQEVSSPRKETSPRNLGTPLFHERSYIEKTFRDLKEEFHRICLLAKAQKDHLSKLNVPSAAPETQCSMPIQCTDKTDKQEVLFKPQAKDDINRGALCITSVTPRGLGQDEEDTSFESLSKLNVKFPPTDNDSTFLHSTPERPDVLGSVTSETVCQDQFNMEPRDNPGNFVKTEETLFEIQGIDPIASAIQNLKTTDKTKPSNTCIRTSLDRAPCLPPGDHNALFVNTFPLQDPSDAPFPSLDSPGKAIRGPQQPIWKPFPNQDSDLSVLSGTGSELHIPRVCEFCQAVFPPSITSRGDFLRHLNSHFNGET", "length": 422, "header": "tr|F6R2Z7-1|F6R2Z7_BOVIN Isoform 1 of TRAF family member associated NFKB activator OS=Bos taurus OX=9913 GN=TANK PE=4 SV=1 CANONICAL=F6R2Z7-1" }, "isoforms": [ { "isoform_ac": "A0A3Q1LUT1-1", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1LUT1/entry", "sequence": { "sequence": "MDKNIGEQLNKAYEAFRQACMDRDSAVKELQQKTENYEQRIREQQEQLSLQQTIIDKLTSQLLLVNSSRDNSCGYVPLLEDSEARKNNLTLDQPHDKAKSGIPREKESKVRRQEVSSPRKETSPRNLGTPLFHERSYIEKTFRDLKEEFHRICLLAKAQKDHLSKLNVPSAAPETQCSMPIQCTDKTDKQEVLFKPQAKDDINRGALCITSVTPRGLGQDEEDTSFESLSKLNVKFPPTDNDSTFLHSTPERPDVLGSVTSETVCQDQFNMEPRDNPGNFVKTEETLFEIQGIDPIASAIQNLKTTDKTKPSNTCIRTSLDRAPCLPPGDHNALFVNTFPLQDPSDAPFPSLDSPGKAIRGPQQSVQSCFSRWHPALCICFLCCSKGNSCPFGSPFLIKTVTYRY", "length": 405, "header": "tr|A0A3Q1LUT1-1|F6R2Z7_BOVIN Computationally mapped isoform of TRAF family member associated NFKB activator OS=Bos taurus OX=9913 GN=TANK PE=4 SV=1 CANONICAL=F6R2Z7-1" }, "locus": { "chromosome": "2", "start_pos": 35196268, "end_pos": 35144197, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000078254.2", "url": "https://www.ensembl.org/id/ENSBTAT00000078254.2" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000061113.1", "url": "https://www.ensembl.org/id/ENSBTAP00000061113.1" } ] } }, { "isoform_ac": "A0AAA9RXB9-1", "url": "https://www.uniprot.org/uniprotkb/A0AAA9RXB9/entry", "sequence": { "sequence": "MKLLHGPFPSHRSVIYFIIYSDATGHRGMDKNIGEQLNKAYEAFRQACMDRDSAVKELQQKTENYEQRIREQQEQLSLQQTIIDKLTSQLLLVNSSRDNSCGYVPLLEDSEARKNNLTLDQPHDKAKSGIPREKESKVRRQEVSSPRKETSPRNLGTPLFHERSYIEKTFRDLKEEFHRICLLAKAQKDHLSKLNVPSAAPETQCSMPIQCTDKTDKQEVLFKPQAKDDINRGALCITSVTPRGLGQDEEDTSFESLSKLNVKFPPTDNDSTFLHSTPERPDVLGSVTSETVCQDQFNMEPRDNPGNFVKTEETLFEIQGIDPIASAIQNLKTTDKTKPSNTCIRTSLDRAPCLPPGDHNALFVNTFPLQDPSDAPFPSLDSPGKAIRGPQQPIWKPFPNQDSDLSVLSGTGSELHIPRVCEFCQAVFPPSITSRGDFLRHLNSHFNGET", "length": 450, "header": "tr|A0AAA9RXB9-1|F6R2Z7_BOVIN Computationally mapped isoform of TRAF family member associated NFKB activator OS=Bos taurus OX=9913 GN=TANK PE=4 SV=1 CANONICAL=F6R2Z7-1" }, "locus": { "chromosome": "2", "start_pos": 35219876, "end_pos": 35144069, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000091288.1", "url": "https://www.ensembl.org/id/ENSBTAT00000091288.1" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000078152.1", "url": "https://www.ensembl.org/id/ENSBTAP00000078152.1" } ] } }, { "isoform_ac": "A0AAA9TGW9-1", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TGW9/entry", "sequence": { "sequence": "MSRSVIYFIIYSDATGHRGMDKNIGEQLNKAYEAFRQACMDRDSAVKELQQKTENYEQRIREQQEQLSLQQTIIDKLTSQLLLVNSSRDNSCGYVPLLEDSEARKNNLTLDQPHDKAKSGIPREKESKVRRQEVSSPRKETSPRNLGTPLFHERSYIEKTFRDLKEEFHRICLLAKAQKDHLSKLNVPSAAPETQCSMPIQCTDKTDKQEVLFKPQAKDDINRGALCITSVTPRGLGQDEEDTSFESLSKLNVKFPPTDNDSTFLHSTPERPDVLGSVTSETVCQDQFNMEPRDNPGNFVKTEETLFEIQGIDPIASAIQNLKTTDKTKPSNTCIRTSLDRAPCLPPGDHNALFVNTFPLQDPSDAPFPSLDSPGKAIRGPQQPIWKPFPNQDSDLSVLSGTGSELHIPRVCEFCQAVFPPSITSRGDFLRHLNSHFNGET", "length": 441, "header": "tr|A0AAA9TGW9-1|F6R2Z7_BOVIN Computationally mapped isoform of TRAF family member associated NFKB activator OS=Bos taurus OX=9913 GN=TANK PE=4 SV=1 CANONICAL=F6R2Z7-1" }, "locus": { "chromosome": "2", "start_pos": 35217693, "end_pos": 35144069, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000096828.1", "url": "https://www.ensembl.org/id/ENSBTAT00000096828.1" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000096295.1", "url": "https://www.ensembl.org/id/ENSBTAP00000096295.1" } ] } }, { "isoform_ac": "A0AAA9TT66-1", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TT66/entry", "sequence": { "sequence": "MSRSVIYFIIYSDATGHRGMDKNIGEQLNKAYEAFRQACMDRDSAVKELQQKQTENYEQRIREQQEQLSLQQTIIDKLTSQLLLVNSSRDNSCGYVPLLEDSEARKNNLTLDQPHDKAKSGIPREKESKVRRQEVSSPRKETSPRNLGTPLFHERSYIEKTFRDLKEEFHRICLLAKAQKDHLSKLNVPSAAPETQCSMPIQCTDKTDKQEVLFKPQAKDDINRGALCITSVTPRGLGQDEEDTSFESLSKLNVKFPPTDNDSTFLHSTPERPDVLGSVTSETVCQDQFNMEPRDNPGNFVKTEETLFEIQGIDPIASAIQNLKTTDKTKPSNTCIRTSLDRAPCLPPGDHNALFVNTFPLQDPSDAPFPSLDSPGKAIRGPQQPIWKPFPNQDSDLSVLSGTGSELHIPRVCEFCQAVFPPSITSRGDFLRHLNSHFNGET", "length": 442, "header": "tr|A0AAA9TT66-1|F6R2Z7_BOVIN Computationally mapped isoform of TRAF family member associated NFKB activator OS=Bos taurus OX=9913 GN=TANK PE=4 SV=1 CANONICAL=F6R2Z7-1" }, "locus": { "chromosome": "2", "start_pos": 35217693, "end_pos": 35144069, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000124384.1", "url": "https://www.ensembl.org/id/ENSBTAT00000124384.1" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000099720.1", "url": "https://www.ensembl.org/id/ENSBTAP00000099720.1" } ] } }, { "isoform_ac": "F6R2Z7-1", "url": "https://www.uniprot.org/uniprotkb/F6R2Z7/entry", "sequence": { "sequence": "MDKNIGEQLNKAYEAFRQACMDRDSAVKELQQKTENYEQRIREQQEQLSLQQTIIDKLTSQLLLVNSSRDNSCGYVPLLEDSEARKNNLTLDQPHDKAKSGIPREKESKVRRQEVSSPRKETSPRNLGTPLFHERSYIEKTFRDLKEEFHRICLLAKAQKDHLSKLNVPSAAPETQCSMPIQCTDKTDKQEVLFKPQAKDDINRGALCITSVTPRGLGQDEEDTSFESLSKLNVKFPPTDNDSTFLHSTPERPDVLGSVTSETVCQDQFNMEPRDNPGNFVKTEETLFEIQGIDPIASAIQNLKTTDKTKPSNTCIRTSLDRAPCLPPGDHNALFVNTFPLQDPSDAPFPSLDSPGKAIRGPQQPIWKPFPNQDSDLSVLSGTGSELHIPRVCEFCQAVFPPSITSRGDFLRHLNSHFNGET", "length": 422, "header": "tr|F6R2Z7-1|F6R2Z7_BOVIN Isoform 1 of TRAF family member associated NFKB activator OS=Bos taurus OX=9913 GN=TANK PE=4 SV=1 CANONICAL=F6R2Z7-1" }, "locus": { "chromosome": "2", "start_pos": 35196268, "end_pos": 35144069, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000046172.3", "url": "https://www.ensembl.org/id/ENSBTAT00000046172.3" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000043495.2", "url": "https://www.ensembl.org/id/ENSBTAP00000043495.2" } ] } } ], "glycosylation": [], "phosphorylation": 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"categories": [ "Protein Classification" ] }, { "id": "A0A3Q1N4Q1", "url": "https://www.orthodb.org/?gene=A0A3Q1N4Q1", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR24070", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR24070", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00071", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00071", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "R-BTA-1632852", "url": "https://www.reactome.org/PathwayBrowser/#R-BTA-1632852", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "R-BTA-165159", "url": "https://www.reactome.org/PathwayBrowser/#R-BTA-165159", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "R-BTA-166208", "url": "https://www.reactome.org/PathwayBrowser/#R-BTA-166208", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "R-BTA-380972", 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"A0A3Q1N4Q1", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1N4Q1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A3Q1N4Q1-1", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1N4Q1-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0AAA9RUD6", "url": "https://www.uniprot.org/uniprotkb/A0AAA9RUD6", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0AAA9RUD6-1", "url": "https://www.uniprot.org/uniprotkb/A0AAA9RUD6-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0AAA9SDW2", "url": "https://www.uniprot.org/uniprotkb/A0AAA9SDW2", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0AAA9SDW2-1", "url": "https://www.uniprot.org/uniprotkb/A0AAA9SDW2-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0AAA9SDZ1", "url": "https://www.uniprot.org/uniprotkb/A0AAA9SDZ1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0AAA9SDZ1-1", "url": "https://www.uniprot.org/uniprotkb/A0AAA9SDZ1-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0AAA9T2Z9", "url": "https://www.uniprot.org/uniprotkb/A0AAA9T2Z9", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0AAA9T2Z9-1", "url": "https://www.uniprot.org/uniprotkb/A0AAA9T2Z9-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0AAA9TVN2", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TVN2", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0AAA9TVN2-1", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TVN2-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "F2Z4I1", "url": "https://www.uniprot.org/uniprotkb/F2Z4I1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "F2Z4I1-1", "url": "https://www.uniprot.org/uniprotkb/F2Z4I1-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MPQSKSRKIAILGYRSVGKSSLTIQFVEGQFVDSYDPTIENTFTKLITVNGQEYHLQLVDTAGQDEYSIFPQTYSIDINGYILVYSVTSIKSFEVIKVIHGKLLDMVGKVQIPIMLVGNKKDLHMERVISYEEGKALAESWNAAFLESSAKENQTAVDVFRRIILEAEKIDGAASQGKSSCSVM", "length": 184, "header": "tr|F2Z4I1-1|F2Z4I1_BOVIN Isoform 1 of GTP-binding protein Rheb OS=Bos taurus OX=9913 GN=RHEB PE=3 SV=1 CANONICAL=F2Z4I1-1" }, "isoforms": [ { "isoform_ac": "A0A3Q1LUV3-1", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1LUV3/entry", "sequence": { "sequence": "TSSHTPRGKSSLTIQFVEGQFVDSYDPTIENTFTKLITVNGQEYHLQLVDTAGQDEYSIFPQTYSIDINGYILVYSVTSIKSFEVIKVIHGKLLDMVGKVQIPIMLVGNKKDLHMERVISYEEGKALAESWNAAFLESSAKENQTAVDVFRRIILEAEKIDGAASQGKSSCSVM", "length": 174, "header": "tr|A0A3Q1LUV3-1|F2Z4I1_BOVIN Computationally mapped isoform of GTP-binding protein Rheb OS=Bos taurus OX=9913 GN=RHEB PE=3 SV=2 CANONICAL=F2Z4I1-1" }, "locus": { "chromosome": "4", "start_pos": 114038506, "end_pos": 114004407, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000076488.2", "url": "https://www.ensembl.org/id/ENSBTAT00000076488.2" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000061140.2", "url": "https://www.ensembl.org/id/ENSBTAP00000061140.2" } ] } }, { "isoform_ac": "A0A3Q1N4Q1-1", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1N4Q1/entry", "sequence": { "sequence": "MVTILSCSVKKRKSSLTIQFVEGQFVDSYDPTIENTFTKLITVNGQEYHLQLVDTAGQDEYSIFPQTYSIDINGYILVYSVTSIKSFEVIKVIHGKLLDMVGKVQIPIMLVGNKKDLHMERVISYEEGKALAESWNAAFLESSAKENQTAVDVFRRIILEAEKIDGAASQGKSSCSVM", "length": 178, "header": "tr|A0A3Q1N4Q1-1|F2Z4I1_BOVIN Computationally mapped isoform of GTP-binding protein Rheb OS=Bos taurus OX=9913 GN=RHEB PE=3 SV=1 CANONICAL=F2Z4I1-1" }, "locus": { "chromosome": "4", "start_pos": 114039635, "end_pos": 114004407, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000078323.2", "url": "https://www.ensembl.org/id/ENSBTAT00000078323.2" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000064835.1", "url": "https://www.ensembl.org/id/ENSBTAP00000064835.1" } ] } }, { "isoform_ac": "A0AAA9RUD6-1", "url": "https://www.uniprot.org/uniprotkb/A0AAA9RUD6/entry", "sequence": { "sequence": "KLSKVTVPFLYPLQTGQLLHILSSTGVVSIFYGKSSLTIQFVEGQFVDSYDPTIENTFTKLITVNGQEYHLQLVDTAGQDEYSIFPQTYSIDINGYILVYSVTSIKSFEVIKVIHGKLLDMVGKVQIPIMLVGNKKDLHMERVISYEEGKALAESWNAAFLESSAKENQTAVDVFRRIILEAEKIDGAASQGKSSCSVM", "length": 199, "header": "tr|A0AAA9RUD6-1|F2Z4I1_BOVIN Computationally mapped isoform of GTP-binding protein Rheb OS=Bos taurus OX=9913 GN=RHEB PE=3 SV=1 CANONICAL=F2Z4I1-1" }, "locus": { "chromosome": "4", "start_pos": 114037631, "end_pos": 114004407, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000113110.1", "url": "https://www.ensembl.org/id/ENSBTAT00000113110.1" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000076787.1", "url": "https://www.ensembl.org/id/ENSBTAP00000076787.1" } ] } }, { "isoform_ac": "A0AAA9SDW2-1", "url": "https://www.uniprot.org/uniprotkb/A0AAA9SDW2/entry", "sequence": { "sequence": "CAHQPLPPRLQLRGKSSLTIQFVEGQFVDSYDPTIENTFTKLITVNGQEYHLQLVDTAGQDEYSIFPQTYSIDINGYILVYSVTSIKSFEVIKVIHGKLLDMVGKVQIPIMLVGNKKDLHMERVISYEEGKALAESWNAAFLESSAKENQTAVDVFRRIILEAEKIDGAASQGKSSCSVM", "length": 180, "header": "tr|A0AAA9SDW2-1|F2Z4I1_BOVIN Computationally mapped isoform of GTP-binding protein Rheb OS=Bos taurus OX=9913 GN=RHEB PE=3 SV=1 CANONICAL=F2Z4I1-1" }, "locus": { "chromosome": "4", "start_pos": 114036203, "end_pos": 114004407, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000116498.1", "url": "https://www.ensembl.org/id/ENSBTAT00000116498.1" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000083583.1", "url": "https://www.ensembl.org/id/ENSBTAP00000083583.1" } ] } }, { "isoform_ac": "A0AAA9SDZ1-1", "url": "https://www.uniprot.org/uniprotkb/A0AAA9SDZ1/entry", "sequence": { "sequence": "IHSFINLKNHGKSSLTIQFVEGQFVDSYDPTIENTFTKLITVNGQEYHLQLVDTAGQDEYSIFPQTYSIDINGYILVYSVTSIKSFEVIKVIHGKLLDMVGKVQIPIMLVGNKKDLHMERVISYEEGKALAESWNAAFLESSAKENQTAVDVFRRIILEAEKIDGAASQGKSSCSVM", "length": 177, "header": "tr|A0AAA9SDZ1-1|F2Z4I1_BOVIN Computationally mapped isoform of GTP-binding protein Rheb OS=Bos taurus OX=9913 GN=RHEB PE=3 SV=1 CANONICAL=F2Z4I1-1" }, "locus": { "chromosome": "4", "start_pos": 114033268, "end_pos": 114004407, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000093235.1", "url": "https://www.ensembl.org/id/ENSBTAT00000093235.1" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000081807.1", "url": "https://www.ensembl.org/id/ENSBTAP00000081807.1" } ] } }, { "isoform_ac": "A0AAA9T2Z9-1", "url": "https://www.uniprot.org/uniprotkb/A0AAA9T2Z9/entry", "sequence": { "sequence": "SELLEGTGGFGKTLQVAGGKSSLTIQFVEGQFVDSYDPTIENTFTKLITVNGQEYHLQLVDTAGQDEYSIFPQTYSIDINGYILVYSVTSIKSFEVIKVIHGKLLDMVGKVQIPIMLVGNKKDLHMERVISYEEGKALAESWNAAFLESSAKENQTAVDVFRRIILEAEKIDGAASQGKSSCSVM", "length": 185, "header": "tr|A0AAA9T2Z9-1|F2Z4I1_BOVIN Computationally mapped isoform of GTP-binding protein Rheb OS=Bos taurus OX=9913 GN=RHEB PE=3 SV=1 CANONICAL=F2Z4I1-1" }, "locus": { "chromosome": "4", "start_pos": 114031597, "end_pos": 114004407, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000135617.1", "url": "https://www.ensembl.org/id/ENSBTAT00000135617.1" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000090991.1", "url": "https://www.ensembl.org/id/ENSBTAP00000090991.1" } ] } }, { "isoform_ac": "A0AAA9TVN2-1", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TVN2/entry", "sequence": { "sequence": "WRLLPAYTAAAELNRLRKRPKTRLRSEDLSASPERGNRRVLIKEHCIVVHSDLSWDLNHREGGKSSLTIQFVEGQFVDSYDPTIENTFTKLITVNGQEYHLQLVDTAGQDEYSIFPQTYSIDINGYILVYSVTSIKSFEVIKVIHGKLLDMVGKVQIPIMLVGNKKDLHMERVISYEEGKALAESWNAAFLESSAKENQTAVDVFRRIILEAEKIDGAASQGKSSCSVM", "length": 229, "header": "tr|A0AAA9TVN2-1|F2Z4I1_BOVIN Computationally mapped isoform of GTP-binding protein Rheb OS=Bos taurus OX=9913 GN=RHEB PE=3 SV=1 CANONICAL=F2Z4I1-1" }, "locus": { "chromosome": "4", "start_pos": 114031091, "end_pos": 114004407, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000130740.1", "url": "https://www.ensembl.org/id/ENSBTAT00000130740.1" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000100642.1", "url": "https://www.ensembl.org/id/ENSBTAP00000100642.1" } ] } }, { "isoform_ac": "F2Z4I1-1", "url": "https://www.uniprot.org/uniprotkb/F2Z4I1/entry", "sequence": { "sequence": "MPQSKSRKIAILGYRSVGKSSLTIQFVEGQFVDSYDPTIENTFTKLITVNGQEYHLQLVDTAGQDEYSIFPQTYSIDINGYILVYSVTSIKSFEVIKVIHGKLLDMVGKVQIPIMLVGNKKDLHMERVISYEEGKALAESWNAAFLESSAKENQTAVDVFRRIILEAEKIDGAASQGKSSCSVM", "length": 184, "header": "tr|F2Z4I1-1|F2Z4I1_BOVIN Isoform 1 of GTP-binding protein Rheb OS=Bos taurus OX=9913 GN=RHEB PE=3 SV=1 CANONICAL=F2Z4I1-1" }, "locus": { "chromosome": "4", "start_pos": 114056679, "end_pos": 114004407, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000006102.7", "url": "https://www.ensembl.org/id/ENSBTAT00000006102.7" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000050644.2", "url": "https://www.ensembl.org/id/ENSBTAP00000050644.2" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [ { "id": "R-BTA-1632852", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-BTA-1632852", "resource": "Reactome", "description": "Macroautophagy" }, { "id": "R-BTA-165159", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-BTA-165159", "resource": "Reactome", "description": "MTOR signalling" }, { "id": "R-BTA-166208", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-BTA-166208", "resource": "Reactome", "description": "mTORC1-mediated signalling" }, { "id": "R-BTA-380972", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-BTA-380972", "resource": "Reactome", "description": "Energy dependent regulation of mTOR by LKB1-AMPK" }, { "id": "R-BTA-5628897", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-BTA-5628897", "resource": "Reactome", "description": "TP53 Regulates Metabolic Genes" }, { "id": "R-BTA-8943724", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-BTA-8943724", "resource": "Reactome", "description": "Regulation of PTEN gene transcription" }, { "id": "R-BTA-9639288", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-BTA-9639288", "resource": "Reactome", "description": "Amino acids regulate mTORC1" } ], "orthologs": [ { "uniprot_canonical_ac": "F2Z5R2-1", "protein_name": "GTP-binding protein Rheb", "gene_name": "RHEB", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MPQSKSRKIAILGYRSVGKSSLTIQFVEGQFVDSYDPTIENTFTKLITVNGQEYHLQLVDTAGQDEYSIFPQTYSIDINGYILVYSVTSIKSFEVIKVIHGKLLDMVGKVQIPIMLVGNKKDLHMERVISYEEGKALAESWNAAFLESSAKENQTAVDVFRRIILEAEKIDGAASQGKSSCSVM", "length": 184 }, "evidence": [ { "id": "F2Z4I1", "url": "https://omabrowser.org/oma/group/F2Z4I1/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "P25378-1", "protein_name": "GTP-binding protein RHB1", "gene_name": "RHB1", "tax_id": 559292, "organism": "Saccharomyces cerevisiae S288C", "sequence": { "sequence": "MEYATMSSSNSTHNFQRKIALIGARNVGKTTLTVRFVESRFVESYYPTIENEFTRIIPYKSHDCTLEILDTAGQDEVSLLNIKSLTGVRGIILCYSIINRASFDLIPILWDKLVDQLGKDNLPVILVGTKADLGRSTKGVKRCVTKAEGEKLASTIGSQDKRNQAAFIECSAELDYNVEETFMLLLKQMERVEGTLGLDAENNNKCSIM", "length": 209 }, "evidence": [ { "id": "F2Z4I1", "url": "https://omabrowser.org/oma/group/F2Z4I1/", "database": "OMA" } ], "glygen_name": "Yeast", "common_name": "Baker's yeast" }, { "uniprot_canonical_ac": "Q15382-1", "protein_name": "GTP-binding protein Rheb", "gene_name": "RHEB", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MPQSKSRKIAILGYRSVGKSSLTIQFVEGQFVDSYDPTIENTFTKLITVNGQEYHLQLVDTAGQDEYSIFPQTYSIDINGYILVYSVTSIKSFEVIKVIHGKLLDMVGKVQIPIMLVGNKKDLHMERVISYEEGKALAESWNAAFLESSAKENQTAVDVFRRIILEAEKMDGAASQGKSSCSVM", "length": 184 }, "evidence": [ { "id": "F2Z4I1", "url": "https://omabrowser.org/oma/group/F2Z4I1/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "Q550Q4-1", "protein_name": "GTP-binding protein Rheb homolog", "gene_name": "rheb", "tax_id": 44689, "organism": "Dictyostelium discoideum", "sequence": { "sequence": "MAPQKHRKICVMGSRAVGKSTITMQFVESHCPDSYHPTIENTYQKIIRHQGQEYSVEIIDTAGQDEYSILQKQYSIGIHGYILVYSVTSVSSLEVIKVLNDKILSSLGAEKIPRVLVGNKSDLDNERNISRDQGIQLANEWECAFVECSGKNNENVEEVFKQILNEVNKGSTGPEPPQKEGCILM", "length": 185 }, "evidence": [ { "id": "F2Z4I1", "url": "https://omabrowser.org/oma/group/F2Z4I1/", "database": "OMA" } ], "glygen_name": "Cellular slime mold", "common_name": "Social amoeba" }, { "uniprot_canonical_ac": "Q62639-1", "protein_name": "GTP-binding protein Rheb", "gene_name": "Rheb", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MPQSKSRKIAILGYRSVGKSSLTIQFVEGQFVDSYDPTIENTFTKLITVNGQEYHLQLVDTAGQDEYSIFPQTYSIDINGYILVYSVTSIKSFEVIKVIHGKLLDMVGKVQIPIMLVGNKKDLHMERVISYEEGKALAESWNAAFLESSAKENQTAVDVFRRIILEAEKIDGAASQGKSSCSVM", "length": 184 }, "evidence": [ { "id": "F2Z4I1", "url": "https://omabrowser.org/oma/group/F2Z4I1/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "Q921J2-1", "protein_name": "GTP-binding protein Rheb", "gene_name": "Rheb", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MPQSKSRKIAILGYRSVGKSSLTIQFVEGQFVDSYDPTIENTFTKLITVNGQEYHLQLVDTAGQDEYSIFPQTYSIDINGYILVYSVTSIKSFEVIKVIHGKLLDMVGKVQIPIMLVGNKKDLHMERVISYEEGKALAESWNAAFLESSAKENQTAVDVFKRIILEAEKIDGAASQGKSSCSVM", "length": 184 }, "evidence": [ { "id": "F2Z4I1", "url": "https://omabrowser.org/oma/group/F2Z4I1/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q9VND8-1", "protein_name": "GTP-binding protein Rheb homolog", "gene_name": "Rheb", "tax_id": 7227, "organism": "Drosophila melanogaster", "sequence": { "sequence": "MPTKERHIAMMGYRSVGKSSLCIQFVEGQFVDSYDPTIENTFTKIERVKSQDYIVKLIDTAGQDEYSIFPVQYSMDYHGYVLVYSITSQKSFEVVKIIYEKLLDVMGKKYVPVVLVGNKIDLHQERTVSTEEGKKLAESWRAAFLETSAKQNESVGDIFHQLLILIENENGNPQEKSGCLVS", "length": 182 }, "evidence": [ { "id": "F2Z4I1", "url": "https://omabrowser.org/oma/group/F2Z4I1/", "database": "OMA" } ], "glygen_name": "Fruit fly", "common_name": "Fruit fly" } ], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 6, "go_terms": [ { "name": "Golgi membrane", "id": "GO:0000139", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000139", "evidence": [ { "database": "UniProtKB", "id": "F2Z4I1", "url": "https://www.uniprot.org/uniprotkb/F2Z4I1" } ], "pmid": "" }, { "name": "lysosomal membrane", "id": "GO:0005765", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005765", "evidence": [ { "database": "UniProtKB", "id": "F2Z4I1", "url": "https://www.uniprot.org/uniprotkb/F2Z4I1" } ], "pmid": "" }, { "name": "endoplasmic reticulum membrane", "id": "GO:0005789", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005789", "evidence": [ { "database": "UniProtKB", "id": "F2Z4I1", "url": "https://www.uniprot.org/uniprotkb/F2Z4I1" } ], "pmid": "" }, { "name": "postsynaptic density", "id": "GO:0014069", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0014069", "evidence": [ { "database": "UniProtKB", "id": "F2Z4I1", "url": "https://www.uniprot.org/uniprotkb/F2Z4I1" } ], "pmid": "" }, { "name": "spliceosomal complex", "id": "GO:0005681", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005681", "evidence": [ { "database": "UniProtKB", "id": "F2Z4I1", "url": "https://www.uniprot.org/uniprotkb/F2Z4I1" } ], "pmid": "" }, { "name": "plasma membrane", "id": "GO:0005886", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005886", "evidence": [ { "database": "UniProtKB", "id": "F2Z4I1", "url": "https://www.uniprot.org/uniprotkb/F2Z4I1" } ], "pmid": "" } ] }, { "name": "Molecular Function", "total": 7, "go_terms": [ { "name": "GTPase activity", "id": "GO:0003924", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003924", "evidence": [ { "database": "UniProtKB", "id": "F2Z4I1", "url": "https://www.uniprot.org/uniprotkb/F2Z4I1" } ], "pmid": "" }, { "name": "GTP binding", "id": "GO:0005525", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005525", "evidence": [ { "database": "UniProtKB", "id": "F2Z4I1", 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"uniprot_id": "F6RFM1_BOVIN", "mass": { "chemical_mass": 51324.0, "monoisotopic_mass": 51324.0 }, "refseq": { "ac": "XP_010814464", "name": "F-box only protein 47 isoform X1", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_010814464" }, "gene_names": [ { "name": "FBXO47", "type": "recommended", "evidence": [ { "id": "F6RFM1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F6RFM1" } ] }, { "name": "FBXO47", "type": "synonym", "evidence": [ { "id": "XP_010814464", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_010814464" } ] } ], "protein_names": [ { "name": "F-box only protein 47 isoform X1", "type": "synonym", "evidence": [ { "id": "XP_010814464", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_010814464" } ] }, { "name": "F-box protein 47", "type": "synonym", "evidence": [ { "id": "F6RFM1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F6RFM1/entry#names_and_taxonomy" } ] } ], "function": [], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Bos taurus", "taxid": 9913, "evidence": [ { "database": "UniProtKB", "id": "F6RFM1", "url": "https://www.uniprot.org/uniprotkb/F6RFM1" } ], "common_name": "Bovine", "glygen_name": "Bovine", "reference_species": "Bos taurus [9913]" } ], "gene": [ { "name": "FBXO47", "url": "https://www.uniprot.org/uniprotkb/F6RFM1", "locus": { "chromosome": "19", "start_pos": 39504400, "end_pos": 39531020, "strand": "+", "evidence": [ { "database": "Ensembl Gene", "id": "ENSBTAG00000024983", "url": "https://www.ensembl.org/id/ENSBTAG00000024983" } ] } } ], "crossref": [ { "id": "F6RFM1", "url": "https://alphafold.ebi.ac.uk/entry/F6RFM1", "database": "AlphaFoldDB", "categories": [] }, { "id": "ENSBTAG00000024983", "url": "https://bgee.org/?page=gene&gene_id=ENSBTAG00000024983", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "cd22112", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd22112", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "613655", "url": "https://www.ncbi.nlm.nih.gov/gene/613655", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR001810", "url": "https://www.ebi.ac.uk/interpro/entry/IPR001810", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR036047", "url": "https://www.ebi.ac.uk/interpro/entry/IPR036047", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR038946", "url": "https://www.ebi.ac.uk/interpro/entry/IPR038946", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR056622", "url": "https://www.ebi.ac.uk/interpro/entry/IPR056622", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "AFACVTM", "url": "https://omabrowser.org/oma/group/AFACVTM/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "A0A3Q1LVT1", "url": "https://www.orthodb.org/?gene=A0A3Q1LVT1", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR34098", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR34098", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR34098:SF1", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR34098:SF1", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00646", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00646", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF24467", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF24467", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "XP_010814464", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_010814464", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A3Q1LVT1", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1LVT1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A3Q1LVT1-1", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1LVT1-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0AAA9T7V2", "url": "https://www.uniprot.org/uniprotkb/A0AAA9T7V2", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0AAA9T7V2-1", "url": "https://www.uniprot.org/uniprotkb/A0AAA9T7V2-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "F6RFM1", "url": "https://www.uniprot.org/uniprotkb/F6RFM1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "F6RFM1-1", "url": "https://www.uniprot.org/uniprotkb/F6RFM1-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MTSRVNTSFTLIPNQKYRRSSRRSSCFSNTFDSDSQPLSTLGNFKALPLEIFQIILKYLSVKDISMLSMVSKTVSQHIINYISTSSGSKRLLLQDFHDLELPDREDTAIVEHYRSLGLLFKRCTLLLPTKERLKYIHKILADVSCFKFNGCAAPLQCVGLLCYGIFLQTLTAGWDELECHRVYNFLCELTHLSRKMQTVVCSKPGSARKLELRIRLFCRNVLLDHWTHRSDSAFWLTCILKPWPMVNQARLLYIIFGPISPQDGQVVWQKMIEGPTDESCLKGLAEAIKLLYDTGTKEWTADDVISLVDELSVVPREWLLENNARLLILSGNNICFTFMASKAVNGRTIELAKLIVFLALVSEKELYCMDWAVKMMQKVCKVFSTPVERNNFLQSVADAFACAIMEMLQLVMSGDGDDDDRSFMNLFHLVQAQASFHKEVLYLTMNVLPS", "length": 450, "header": "tr|F6RFM1-1|F6RFM1_BOVIN Isoform 1 of F-box protein 47 OS=Bos taurus OX=9913 GN=FBXO47 PE=4 SV=1 CANONICAL=F6RFM1-1" }, "isoforms": [ { "isoform_ac": "A0A3Q1LVT1-1", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1LVT1/entry", "sequence": { "sequence": "MTSRVNTSFTLIPNQKYRRSSRRSSCFSNTFDSDSQPLSTLGNFKALPLEIFQIILKYLSVKDISMLSMVSKTVSQHIINYISTSSGSKRLLLQDFHDLELPDREDTAIVEHYRSLGLLFKRCTLLLPTKERLKYIHKILADVSCFKFNGCAAPLQCVGLLCYGIFLQTLTAGWDELECHRVYNFLCELTHLSRKMQTVVCSKPGSARKLELRIRLFCRNVLLDHWTHRSDSAFWLTCILKPWPMVNQARLLYIIFGPISPQDGQVVWQKMIEGPTDESCLKGLAEAIKLLYDTGTKEWTADDVISLVDELSVVPREWLLENNARLLILSGNNICFTFMASKAVNGRTIELAKLIVFLALVSEKELYCMDWAVKMMQKVCKVFSTPVERNNFLQSVADAFACAIMEMLQLVMSGDGDDDDRSFMNLFHLVQAQASFHKEDYREHSRNFPGGSEVKASASNVGDPSSSPGSGRSPGEGNGNPL", "length": 482, "header": "tr|A0A3Q1LVT1-1|F6RFM1_BOVIN Computationally mapped isoform of F-box protein 47 OS=Bos taurus OX=9913 GN=FBXO47 PE=4 SV=2 CANONICAL=F6RFM1-1" }, "locus": { "chromosome": "19", "start_pos": 39528107, "end_pos": 39506305, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000075198.2", "url": "https://www.ensembl.org/id/ENSBTAT00000075198.2" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000061282.2", "url": "https://www.ensembl.org/id/ENSBTAP00000061282.2" } ] } }, { "isoform_ac": "A0AAA9T7V2-1", "url": "https://www.uniprot.org/uniprotkb/A0AAA9T7V2/entry", "sequence": { "sequence": "MTSRVNTSFTLIPNQKYRRSSRRSSCFSNTFDSDSQPLSTLGNFKALPLEIFQIILKYLSVKDISMLSMVSKTVSQHIINYISTSSGSKRLLLQDFHDLELPDREDTAIVEHYRSLGLLFKRCTLLLPTKERLKYIHKILADTLTAGWDELECHRVYNFLCELTHLSRKMQTVVCSKPGSARKLELRIRLFCRNVLLDHWTHRSDSAFWLTCILKPWPMVNQARLLYIIFGPISPQDGQVVWQKMIEGPTDESCLKGLAEAIKLLYDTGTKEWTADDVISLVDELSVVPREWLLENNARLLILSGNNICFTFMASKAVNGRTIELAKLIVFLALVSEKELYCMDWAVKMMQKVCKVFSTPVERNNFLQSVADAFACAIMEMLQLVMSGDGDDDDRSFMNLFHLVQAQASFHKEVLYLTMNVLPS", "length": 424, "header": "tr|A0AAA9T7V2-1|F6RFM1_BOVIN Computationally mapped isoform of F-box protein 47 OS=Bos taurus OX=9913 GN=FBXO47 PE=4 SV=1 CANONICAL=F6RFM1-1" }, "locus": { "chromosome": "19", "start_pos": 39528107, "end_pos": 39506866, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000131473.1", "url": "https://www.ensembl.org/id/ENSBTAT00000131473.1" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000094813.1", "url": "https://www.ensembl.org/id/ENSBTAP00000094813.1" } ] } }, { "isoform_ac": "F6RFM1-1", "url": "https://www.uniprot.org/uniprotkb/F6RFM1/entry", "sequence": { "sequence": "MTSRVNTSFTLIPNQKYRRSSRRSSCFSNTFDSDSQPLSTLGNFKALPLEIFQIILKYLSVKDISMLSMVSKTVSQHIINYISTSSGSKRLLLQDFHDLELPDREDTAIVEHYRSLGLLFKRCTLLLPTKERLKYIHKILADVSCFKFNGCAAPLQCVGLLCYGIFLQTLTAGWDELECHRVYNFLCELTHLSRKMQTVVCSKPGSARKLELRIRLFCRNVLLDHWTHRSDSAFWLTCILKPWPMVNQARLLYIIFGPISPQDGQVVWQKMIEGPTDESCLKGLAEAIKLLYDTGTKEWTADDVISLVDELSVVPREWLLENNARLLILSGNNICFTFMASKAVNGRTIELAKLIVFLALVSEKELYCMDWAVKMMQKVCKVFSTPVERNNFLQSVADAFACAIMEMLQLVMSGDGDDDDRSFMNLFHLVQAQASFHKEVLYLTMNVLPS", "length": 450, "header": "tr|F6RFM1-1|F6RFM1_BOVIN Isoform 1 of F-box protein 47 OS=Bos taurus OX=9913 GN=FBXO47 PE=4 SV=1 CANONICAL=F6RFM1-1" }, "locus": { "chromosome": "19", "start_pos": 39528107, "end_pos": 39506866, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000008714.7", "url": "https://www.ensembl.org/id/ENSBTAT00000008714.7" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000008714.6", "url": "https://www.ensembl.org/id/ENSBTAP00000008714.6" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [], "orthologs": [ { "uniprot_canonical_ac": "A0A287APT5-1", "protein_name": "F-box protein 47", "gene_name": "FBXO47", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MASRVNSSFTLIPNQKYRRSNRRSSYFSNNLASDSQPLSTLGNFKALPLEIFQIILRYLSVKDISMLSMVSKTISQHIINYISTSSGSKRLLLPDFHNLELPDRKQESAILEYYRSLGLLFKRCTLLLPTKERLKYIHKILAEVSCFKFSGCAAPLQCLGLPCYGMFLQTLTAGWDELECHRVFNFLCELTNLPRKMQTVVCSKPGSARKLELRIRLFCRRVLLDHWTHRSDSAFWLTRILKPWPMVNQARLLYIIFGPVSPQDGQVVWQRMIEGPTDEPSLKGLADAIKLLYDTGTKEWTADDIISLVDELSVVPREWLLENNARLLILSGNNICFTFMASKAVNGRAIELARLIVFLALVCEKELYCMDWAVKMMQKVCKVFSTPVERNNFLQSVANAFACVTMEMLQSVMSGDRDEDDRSFLNLYHLVQAQANFHKEVLSLTVNTLST", "length": 451 }, "evidence": [ { "id": "F6RFM1", "url": "https://omabrowser.org/oma/group/F6RFM1/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "A0ABK0LX24-1", "protein_name": "F-box protein 47", "gene_name": "Fbxo47", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MASRVNTTFTLIPSSKCRRLNHQSSDFCNTLDSDPQLLSTLGNFKVLPLEILHIILRYLSVKDIGMLSMVSKTVSQHIINYISTSSGSRRLLLQNFHDLDLPGTKEETALLEHYRALGLLFKRCTLLLPTKERLKYIQKILSEVPCFKFSGCSAPLQCLGLSCYGMFLQTLTAGWDELECHRVYNFLCEQTNLSRKMQTVVCNKPGSARKLELRVRLFCRNVLLDHWTHRSDSAFWLTRILKPWPMVNQARLLYIIFGPTSPHDGQVIWQEMIEGPTDESSLKGLANAIKLLYDTGAKGWTADDVISLVDELSVVPREWLLENNARLLILSGNNICFTFMASKAVNGRAIELARLIVFLALVCEKELYCMDWTVRMMQKVCKVFNTATERKSFLQSVANAFACVTMEMLQPVMSGERDDDDRGFLNLFHLLHAQANFHKEVLYLTMNAVSS", "length": 451 }, "evidence": [ { "id": "F6RFM1", "url": "https://omabrowser.org/oma/group/F6RFM1/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "A2A6H3-1", "protein_name": "F-box only protein 47", "gene_name": "Fbxo47", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MASRVNTSFTLIPKQKCRRSNHHSSYFCNTLDSDPQLLSTLGNFKVLPLEILHIILRYLSVKDIGMLSMVSKTVSQHIINYISTSSGSRRLLLQNFHDLDLPGTKEETALLEHYRALGLLFKRCTLLLPTKERLKYIHKILSEVSCFKFSGCSVPLQCLGLSCYGMFLQTLTAGWDELECHRVYNFLCELTNLSRKMQTVVCNKPGSARKLELRVRLFCRNVLLDHWTHRSDSAFWLTRILKPWPMVNQARLLYIIFGPTSPHDGQVIWQEMIEGPTDESSLKGLANAIKLLYDTGAKGWTADDVISLVDELSVVPREWLLENNARLLILSGNNICFTFMASKAVNGRAVELARLVVFLALVCEKELYCMDWTVRMMQKVCKVFSTAAERKSFLQSIANAFACVTMEMLQPVMSGDRDDDDRGFLNLFHLLHAQANFHKEVLYLTMNAISS", "length": 451 }, "evidence": [ { "id": "F6RFM1", "url": "https://omabrowser.org/oma/group/F6RFM1/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "E1C4J7-1", "protein_name": "F-box protein 47", "gene_name": "FBXO47", "tax_id": 9031, "organism": "Gallus gallus", "sequence": { "sequence": "MTSTARTSCTSGPNQKHRGSNHHSRQSCNTVDTDSQSLSTLGYFKTLPLEIFQMLLSYLSVKDISVLSMVSKAISNRLINYISTPSGNRRLLLQDFHNIKLSGKREGSYIIEHYKSLGLLLKRCTLLLPTKDRLKYIHKVLSEVSCFKLNGCPSPLHCVGLQCYGVFLQILIAGWDELECHRVFNFLCELSNLPRKVQAVVSCKPGSARKLELRIRLFCRSVLLNHWIHRSDSAFWLTRILKPWPMVNQARLLYIIFGPVSSLDGHVVWQKMIEGPTDETSLKGLADAIKLLYDPEAREWTADDVISLVDELSVVPREWLLENNARLLILSGNNICFTFMASKAVNGRAVELARLVVFLALVCEKDLYCMDWAVKMMQKVCKVFSTPGERNIFLQSVENAFAHMVMDMLQAVLAGNRDQEDISFLNLFHLVNAQANFHKEILYLTMRSGSNTI", "length": 453 }, "evidence": [ { "id": "F6RFM1", "url": "https://omabrowser.org/oma/group/F6RFM1/", "database": "OMA" } ], "glygen_name": "Chicken", "common_name": "Chicken" }, { "uniprot_canonical_ac": "Q5MNV8-1", "protein_name": "F-box only protein 47", "gene_name": "FBXO47", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MASRINTNFTLIPNQKLRRSNRQTSCYSKTLGSGFQPISTFGNFKALPLEIFQIILKYLSVKDISMLSMVSKTVSQHIINYISTSSGSKRLLLQDFHNLELPDRRQDSAILEHYRSLGLLFKRCTLLLPTKERLKYIHKILTEVSCFKFNGCAAPMQCLGLTCYGMFLQTLTAGWDELECHRVYNFLCELTNLCRKIQMAVCSKPGSAQKLELRIRLFCRNVLLDHWTHRSDSAFWLTRILKPWPMVNQARLLYIIFGPISPQDGQVVWQEMIEEPTDEFSLKGLADAIKLLYDASTKEWTADDVISLVDELSVVPREWLLENNARLLMLSGNNICFSFMASKAVNGRTIELARLVVFLALVCEKELYCMDWTVKMMQKVCKVFSTPVERKNFLQNVANAFACVIMEMLQSIMSGDRDEDDRSFLNLFHLVHAQANFHKEVLYLTMNTPLST", "length": 452 }, "evidence": [ { "id": "F6RFM1", "url": "https://omabrowser.org/oma/group/F6RFM1/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" } ], "go_annotation": {}, "pro_annotation": [], "site_annotation": [ { "start_pos": 6, "end_pos": 8, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "F6RFM1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F6RFM1" }, { "id": "PS50181", "database": "PROSITE", "url": "https://prosite.expasy.org/PS50181" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "F-box", "eco_id": "ECO_0000259", "start_pos": 41, "end_pos": 91, "start_aa": "Leu", "end_aa": "Leu", "glycosite_overlap": [] } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" }, { "name": "homologset.oma", "label": "OMA Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 6, "end_pos": 8 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ], "tool_support": { "graph_view": "yes" } }, { "uniprot_canonical_ac": "F6QVM6-1", "uniprot_ac": "F6QVM6", "uniprot_id": "F6QVM6_BOVIN", "mass": { "chemical_mass": 49432.0, "monoisotopic_mass": 49432.0 }, "refseq": { "ac": "NP_001092601", "name": "transmembrane protein 44", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001092601" }, "gene_names": [ { "name": "TMEM44", "type": "recommended", "evidence": [ { "id": "F6QVM6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F6QVM6" } ] }, { "name": "TMEM44", "type": "synonym", "evidence": [ { "id": "NP_001092601", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001092601" } ] } ], "protein_names": [ { "name": "Transmembrane protein 44", "type": "synonym", "evidence": [ { "id": "F6QVM6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F6QVM6/entry#names_and_taxonomy" } ] }, { "name": "transmembrane protein 44", "type": "synonym", "evidence": [ { "id": "NP_001092601", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001092601" } ] } ], "function": [], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Bos taurus", "taxid": 9913, "evidence": [ { "database": "UniProtKB", "id": "F6QVM6", "url": "https://www.uniprot.org/uniprotkb/F6QVM6" } ], "common_name": "Bovine", "glygen_name": "Bovine", "reference_species": "Bos taurus [9913]" } ], "gene": [ { "name": "TMEM44", "url": "https://www.uniprot.org/uniprotkb/F6QVM6", "locus": { "chromosome": "1", "start_pos": 72952214, "end_pos": 72908919, "strand": "-", "evidence": [ { "database": "Ensembl Gene", "id": "ENSBTAG00000002394", "url": "https://www.ensembl.org/id/ENSBTAG00000002394" } ] } } ], "crossref": [ { "id": "F6QVM6", "url": "https://alphafold.ebi.ac.uk/entry/F6QVM6", "database": "AlphaFoldDB", "categories": [] }, { "id": "ENSBTAG00000002394", "url": "https://bgee.org/?page=gene&gene_id=ENSBTAG00000002394", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "614057", "url": "https://www.ncbi.nlm.nih.gov/gene/614057", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR051415", "url": "https://www.ebi.ac.uk/interpro/entry/IPR051415", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "bta:614057", "url": "https://www.genome.jp/dbget-bin/www_bget?bta:614057", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "WGDEAVC", "url": "https://omabrowser.org/oma/group/WGDEAVC/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "A0A3Q1LVU9", "url": "https://www.orthodb.org/?gene=A0A3Q1LVU9", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "F6QVM6", "url": "https://www.orthodb.org/?gene=F6QVM6", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR16201", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR16201", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR16201:SF53", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR16201:SF53", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "NP_001092601", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001092601", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A3Q1LVU9", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1LVU9", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A3Q1LVU9-1", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1LVU9-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "F6QVM6", "url": "https://www.uniprot.org/uniprotkb/F6QVM6", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "F6QVM6-1", "url": "https://www.uniprot.org/uniprotkb/F6QVM6-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MELAMGEAPSRAPALALWDWDYLDRCFARHRVCISFGLWICSSSCWIAVHALLLYLRCGRKSGRDQSALWAACCLLISLCDTIGAILAKQLTIQVFTGTYLAAVDLVNFVSVLFPVCGSKFKSNSGRGSRARKRRRRLQASMFALVLPLSLGPGWALWAAIPWASGRDQGPQRRLLGILVQDNTEILGFLLGGIAALGSWVSRIPPLSRICQGKTFPCIHLWTRLLSALAGLLYASAIVAHDRRPEYLLRATPWLLTSLGRAALDLSIIFLSCVMKSKMRQVLGFASEAGENPDTQALLTGAEKEEENQEAMTENSDWVPLTTLPHCKPLQRMAAISRYMELTIEPVQQVSCSASRLPGDGQTDTGATSLQEPPSYPPVQVIQARVSSSSSSQVSSINSDLEQKYWEALISEQWDPEDVNLGGNKDSMETLRSQAHRWSVKPVDLPSDE", "length": 449, "header": "tr|F6QVM6-1|F6QVM6_BOVIN Isoform 1 of Transmembrane protein 44 OS=Bos taurus OX=9913 GN=TMEM44 PE=4 SV=1 CANONICAL=F6QVM6-1" }, "isoforms": [ { "isoform_ac": "A0A3Q1LVU9-1", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1LVU9/entry", "sequence": { "sequence": "MELAMGEAPSRAPALALWDWDYLDRCFARHRVCISFGLWICSSSCWIAVHALLLYLRCGRKSGRDQSALWAACCLLISLCDTIGAILAKQLTIQVFTGTYLAAVDLVNFVSVLFPVCGSKFKSNSGRGSRARKRRRRLQASMFALVLPLSLGPGWALWAAIPWASGRDQGPQRRLLGILVQDNTEILGFLLGGIAALGSWVSRIPPLSRICQGKTFPCIHLWTRLLSALAGLLYASAIVAHDRRPEYLLRATPWLLTSLGRAALDLSIIFLSCVMKSKMRQVLGFASEAGENPDTQALLTGAEKEEENQEAMTENSDWVPLTTLPHCKPLQRMAAISRYMELTIEPVQQVSCSASRLPGDGQTDTGATSLQEPPSYPPVQVIQARVSSSSSSQVSSINSDLEWDPEDVNLGGNKDSMETLRSQAHRWSVKPVDLPSDE", "length": 438, "header": "tr|A0A3Q1LVU9-1|F6QVM6_BOVIN Computationally mapped isoform of Transmembrane protein 44 OS=Bos taurus OX=9913 GN=TMEM44 PE=4 SV=3 CANONICAL=F6QVM6-1" }, "locus": { "chromosome": "1", "start_pos": 72951210, "end_pos": 72909063, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000083917.3", "url": "https://www.ensembl.org/id/ENSBTAT00000083917.3" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000064794.3", "url": "https://www.ensembl.org/id/ENSBTAP00000064794.3" } ] } }, { "isoform_ac": "F6QVM6-1", "url": "https://www.uniprot.org/uniprotkb/F6QVM6/entry", "sequence": { "sequence": "MELAMGEAPSRAPALALWDWDYLDRCFARHRVCISFGLWICSSSCWIAVHALLLYLRCGRKSGRDQSALWAACCLLISLCDTIGAILAKQLTIQVFTGTYLAAVDLVNFVSVLFPVCGSKFKSNSGRGSRARKRRRRLQASMFALVLPLSLGPGWALWAAIPWASGRDQGPQRRLLGILVQDNTEILGFLLGGIAALGSWVSRIPPLSRICQGKTFPCIHLWTRLLSALAGLLYASAIVAHDRRPEYLLRATPWLLTSLGRAALDLSIIFLSCVMKSKMRQVLGFASEAGENPDTQALLTGAEKEEENQEAMTENSDWVPLTTLPHCKPLQRMAAISRYMELTIEPVQQVSCSASRLPGDGQTDTGATSLQEPPSYPPVQVIQARVSSSSSSQVSSINSDLEQKYWEALISEQWDPEDVNLGGNKDSMETLRSQAHRWSVKPVDLPSDE", "length": 449, "header": "tr|F6QVM6-1|F6QVM6_BOVIN Isoform 1 of Transmembrane protein 44 OS=Bos taurus OX=9913 GN=TMEM44 PE=4 SV=1 CANONICAL=F6QVM6-1" }, "locus": { "chromosome": "1", "start_pos": 72951210, "end_pos": 72909063, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000032260.4", "url": "https://www.ensembl.org/id/ENSBTAT00000032260.4" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000032196.4", "url": "https://www.ensembl.org/id/ENSBTAP00000032196.4" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [ { "id": "bta:614057", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?bta:614057", "resource": "KEGG Pathway" } ], "orthologs": [ { "uniprot_canonical_ac": "A0A8D1QLZ1-1", "protein_name": "Transmembrane protein 44", "gene_name": "TMEM44", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MGEAPSPAPALWNWDYLDRCFARHRVCISFGLWICSSSCWIAAHALLLYLRCGRKPGQDQSALCAACCLLTSLCDTIGAILAKQLTIQVFTGAYLAAIDLVNFVSILFPVCGSGFKSNSGGGSRERKRRQRLRASVFALVLPLSLGPGWAVWAVVPKASGPIPGPQRRLLGSLIQDNTEILGYLLGIIAAFGSWASRMPALSRICRGKTFPSIHLWTRLLSALAGLLYASAIVAHDRQPEYLLRATPWFLTSLGRAALDLAIIFLSWVMKSKMRQALGFASETRESPDTQALLTCAEKEEENQENSDWVPLTTLPHCKPLKKMAAISRYMELTIEPVQQASCSATRLPGDGQTSAGATTLQEPPSFPPVQVIRARVSSSSSSQVSSINSDLEQKYWEALNSEQWDPEDVNPGGNKDNTEIPRSQVHSWSVKPVDLTSDE", "length": 439 }, "evidence": [ { "id": "F6QVM6", "url": "https://omabrowser.org/oma/group/F6QVM6/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "A0A8M2BGN8-1", "protein_name": "Transmembrane protein 44 isoform X1", "gene_name": "tmem44", "tax_id": 7955, "organism": "Danio rerio", "sequence": { "sequence": "MDKSMFLDTVFRWSPEFVKGCLSTYEEHICTSAGFYILSALILLVSCSLLLYHRCSVKTRSKNWGDEAVCALYCFVGNLCSAVGAFLSNQFDFQISMASYMAIMDVVNFLSISFSMYLWFKSRTGRKMRMISRRRRQNFLAVCLLFIMAGSVYLGLPVRSIPVRASPTMRRLFGMFLNDHTENLGYVLGLLAFAISWTSKFPFILKASYLFQNRGEQGSAVLVSSRLLSSVAGALYGSAILLYDTQLKSVIKTMPWILSAICGSILDLSIVVLVCYRSSHKRPSVRSLDSDTESLLGEPSVTGQLCNNNECCRKKHHLSTARGISPKGTDMGLYMDVNIQPMRKVCLKEVTISRDGSSESLPLKRTVRVVRVDEHCSCGSSTDSSSLDSELEWDFGETKSQWTPVEEAPEDLQKVMPLQEWSVGSSGRLGSHVCFCNRAQLAEKLASK", "length": 448 }, "evidence": [ { "id": "F6QVM6", "url": "https://omabrowser.org/oma/group/F6QVM6/", "database": "OMA" } ], "glygen_name": "Zebrafish", "common_name": "Zebrafish" }, { "uniprot_canonical_ac": "D4ADT4-1", "protein_name": "Transmembrane protein 44", "gene_name": "Tmem44", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MLHAEPDNRPGWGASRSRNFPRGRRRLGRAMEEGASTAPPLWNWDYLERCFARRRVCISFGLWICAACCWIAAHTLILYLRCTKKCGQDQSTLCAAFCLLTSLCDTVGAILARQLTIQVFTGAYLAVVDFMNFISILFPVCGSKSKSKSGQSSRERRRRRHLRASVFALALPLSLGPGWAVWTAIPKVSAPVRGPQRRLLGSLLQENPEVFGYLLGTVAAFGSWASRIPPFSNICRGKSLSYIHLWTRFLSALAGLLYASAIVAHDRQPEYLLQATPWFLISLGRAALDLAIIILSCVMKSRMRRAFGFATVEARESADTQALLTCAEKEEENQEARTEDKNSDWVPLTSLSNCKPLKTMTAVSRYLELTVEPAQPAGCSATRLPGDGQTNTGDASLEEPPSYPPIQVIQARVSSSSSSEVSSINSDLEWDPEDVNLERRKDTEFLRSQVHRASLSPVDLTSDD", "length": 464 }, "evidence": [ { "id": "F6QVM6", "url": "https://omabrowser.org/oma/group/F6QVM6/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "E9Q4M0-1", "protein_name": "Transmembrane protein 44", "gene_name": "Tmem44", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MEEGASAAPPLLNWDYLERCFARRRVCISFGLWICAACCWIAAHTLILYLRCTKKCSQDQSTLCAAFCLLTSLCDTVGAILARQLTIQVFTGAYLAAVDFMNFMFTLFPVCGSKSKSKSGQSSRERRRRHLRASVFALALPLSLGPGWAIWTAIPKAPAPVRGPQRRLLGSLLQENPEVFGYLLGAIAAFGSWASRIPPFSNICRGKSLSYIHLWTRFLSALAGLLYASAIVAHDRQPEYLLQATPWFLISLGRAALDLAIIFLSCVIKSRMSRAFRFATAEARESADTQALLTCAEKEEENQEARTEDKNSDWVPLTSLSHCKPLRTMTAISRYMELTIEPAQQAGCSATRLPGDGQTSTRDAASQEPPSYPPIQVIQARVSSSSSSEVSSINSDLEWDPEDVNLERKKDGELLRVQVRRASLSPVDLASDD", "length": 433 }, "evidence": [ { "id": "F6QVM6", "url": "https://omabrowser.org/oma/group/F6QVM6/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "G3GSI5-1", "protein_name": "Transmembrane protein 44 isoform X1", "gene_name": "Tmem44", "tax_id": 10029, "organism": "Cricetulus griseus", "sequence": { "sequence": "MEEGAGTASPLWNWDYLDRCFAHRRVCISFGLWICSACCWIAAHALTLYLRCTKKCGQDQSTLCATFCLLTSLCDTVGAILARQLTIQVFTGAYLAVVDFVNFVSILFPVCGSKSKSKSGRGSRERRRRHLRASVFALALPLCLGPGWAIWAAVPKASVPVRGPQRKLLGSLLQENLEVFGYLLGGIAAIGSWASRIPPFSKICRGKPFSYIHLWTRFLSALAGLLYASAIVAHDRQPEYLLQATPWFLISLGRASLDLAIIFLSCVVKSKMRQAFGFAAKAREGPDTQALLTCTEKEDSQEARTEDQNSDWVPLTSLSHCKPLRTMTAVSRYMELTVEPVQQAGCSATRLPGDGQTSTGDASLQEPPSYPPIQVIQARVSSGSSSEVSSINSDLEQKYWEALNSEQWDPEDVNLERNKNNVESLRSQMHKGSLSPVDLTSDN", "length": 443 }, "evidence": [ { "id": "F6QVM6", "url": "https://omabrowser.org/oma/group/F6QVM6/", "database": "OMA" } ], "glygen_name": "Hamster", "common_name": "Chinese hamster" }, { "uniprot_canonical_ac": "Q2T9K0-1", "protein_name": "Transmembrane protein 44", "gene_name": "TMEM44", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MGEAPSPAPALWDWDYLDRCFARHRVCISFGLWICASSCWIAAHALLLYLRCAQKPRQDQSALCAACCLLTSLCDTVGALLARQLTIQVFTGAYLAAIDLVNFMFILFPVCGSKFKSNSDREARERKRRRQLRASVFALALPLSLGPCWALWVAVPKASATIRGPQRRLLASLLQENTEILGYLLGSVAAFGSWASRIPPLSRIAPPPTLGITTQHEIWRGQMSKPSQSPSRSPSGHWRAAAQRQVLGTEMCRGKTFPSIHLWTRLLSALAGLLYASAIVAHDQHPEYLLRATPWFLTSLGRAALDLAIIFLSCVMKSKMRQALGFAKEARESPDTQALLTCAEKEEENQENLDWVPLTTLSHCKSLRTMTAISRYMELTIEPVQQAGCSATRLPGDGQTSAGDASLQDPPSYPPVQVIRARVSSGSSSEVSSINSDLEWDPEDVNLEGSKENVELLGSQVHQDSVRTAHLSDDD", "length": 475 }, "evidence": [ { "id": "F6QVM6", "url": "https://omabrowser.org/oma/group/F6QVM6/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" } ], "go_annotation": { "categories": [ { "name": "Molecular Function", "total": 1, "go_terms": [ { "name": "basic amino acid transmembrane transporter activity", "id": "GO:0015174", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0015174", "evidence": [ { "database": "UniProtKB", "id": "F6QVM6", "url": "https://www.uniprot.org/uniprotkb/F6QVM6" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [ { "pdb_id": "AF-F6QVM6-F1", "pdb_chain": "global", "start_pos": 1, "end_pos": 449, "overlap": "1.0", "method": "AlphaFold", "type": "alphafold", "resolution": -1.0, "url": "https://data.glygen.org/ln2downloads/pdb/current/AF-F6QVM6-F1.pdb", "url_external": "https://alphafold.ebi.ac.uk/entry/F6QVM6" } ], "lectin_list": [], "domain_list": [], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" }, { "name": "homologset.oma", "label": "OMA Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ], "tool_support": { "graph_view": "yes" } }, { "uniprot_canonical_ac": "F1N575-1", "uniprot_ac": "F1N575", "uniprot_id": "F1N575_BOVIN", "mass": { "chemical_mass": 66410.0, "monoisotopic_mass": 66410.0 }, "refseq": { "ac": "XP_059738619", "name": "TAF5-like RNA polymerase II p300/CBP-associated factor-associated factor 65 kDa subunit 5L isoform X2", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_059738619" }, "gene_names": [ { "name": "TAF5L", "type": "recommended", "evidence": [ { "id": "F1N575", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1N575" } ] }, { "name": "TAF5L", "type": "synonym", "evidence": [ { "id": "XP_059738619", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_059738619" } ] } ], "protein_names": [ { "name": "TAF5-like RNA polymerase II p300/CBP-associated factor-associated factor 65 kDa subunit 5L", "type": "recommended", "evidence": [ { "id": "F1N575", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1N575/entry#names_and_taxonomy" } ] }, { "name": "PCAF-associated factor 65 beta", "type": "synonym", "evidence": [ { "id": "F1N575", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1N575/entry#names_and_taxonomy" } ] }, { "name": "TAF5-like RNA polymerase II p300/CBP-associated factor-associated factor 65 kDa subunit 5L isoform X2", "type": "synonym", "evidence": [ { "id": "XP_059738619", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_059738619" } ] } ], "function": [ { "annotation": "Functions as a component of the PCAF complex. The PCAF complex is capable of efficiently acetylating histones in a nucleosomal context. The PCAF complex could be considered as the human version of the yeast SAGA complex. With TAF6L, acts as an epigenetic regulator essential for somatic reprogramming. Regulates target genes through H3K9ac deposition and MYC recruitment which trigger MYC regulatory network to orchestrate gene expression programs to control embryonic stem cell state.", "evidence": [ { "database": "UniProtKB", "id": "A0AAA9S6I5", "url": "https://www.uniprot.org/uniprotkb/A0AAA9S6I5#function" }, { "database": "UniProtKB", "id": "ARBA00056767", "url": "https://www.uniprot.org/uniprotkb/ARBA00056767#function" }, { "database": "UniProtKB", "id": "F1N575", "url": "https://www.uniprot.org/uniprotkb/F1N575#function" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Bos taurus", "taxid": 9913, "evidence": [ { "database": "UniProtKB", "id": "F1N575", "url": "https://www.uniprot.org/uniprotkb/F1N575" } ], "common_name": "Bovine", "glygen_name": "Bovine", "reference_species": "Bos taurus [9913]" } ], "gene": [ { "name": "TAF5L", "url": "https://www.uniprot.org/uniprotkb/F1N575", "locus": { "chromosome": "28", "start_pos": 1545808, "end_pos": 1576839, "strand": "+", "evidence": [ { "database": "Ensembl Gene", "id": "ENSBTAG00000034225", "url": "https://www.ensembl.org/id/ENSBTAG00000034225" } ] } } ], "crossref": [ { "id": "F1N575", "url": "https://alphafold.ebi.ac.uk/entry/F1N575", "database": "AlphaFoldDB", "categories": [] }, { "id": "ENSBTAG00000034225", "url": "https://bgee.org/?page=gene&gene_id=ENSBTAG00000034225", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "cd00200", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd00200", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "cd08044", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd08044", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "510413", "url": "https://www.ncbi.nlm.nih.gov/gene/510413", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR001680", "url": "https://www.ebi.ac.uk/interpro/entry/IPR001680", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR007582", "url": "https://www.ebi.ac.uk/interpro/entry/IPR007582", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR015943", "url": "https://www.ebi.ac.uk/interpro/entry/IPR015943", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR019775", "url": "https://www.ebi.ac.uk/interpro/entry/IPR019775", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR020472", "url": "https://www.ebi.ac.uk/interpro/entry/IPR020472", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR036322", "url": "https://www.ebi.ac.uk/interpro/entry/IPR036322", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR037264", "url": "https://www.ebi.ac.uk/interpro/entry/IPR037264", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "A0A3Q1LVZ4", "url": "https://www.orthodb.org/?gene=A0A3Q1LVZ4", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "F1N575", "url": "https://www.orthodb.org/?gene=F1N575", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR19879", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR19879", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR19879:SF6", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR19879:SF6", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00400", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00400", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF04494", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF04494", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "XP_059738619", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_059738619", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A3Q1LVZ4", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1LVZ4", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A3Q1LVZ4-1", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1LVZ4-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0AAA9S6I5", "url": "https://www.uniprot.org/uniprotkb/A0AAA9S6I5", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0AAA9S6I5-1", "url": "https://www.uniprot.org/uniprotkb/A0AAA9S6I5-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "F1N575", "url": "https://www.uniprot.org/uniprotkb/F1N575", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "F1N575-1", "url": "https://www.uniprot.org/uniprotkb/F1N575-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MVMKRVRTEQIQMAVSCYLKRRQYGDADGPVKQGLRLSQSTEEMAASLTVQSESGCANIVSAAPCQAEPQQYEVQFGRLRNFLTDSDSQHSHEVMPLLYPLFVYLHLTLIQNSPKSTVESFYSRFHGMFLQNASQKDVIEQLQTTQTIQDILSNFRLRAFLDNKYVVRLQEDSYNYLLRYLQSDNNTALCRILAWHIHLDVQPAKRTDYQLYTSGGSFRGEGGGLEPADMPAPILQNEAALELLQESIKRVKDGPPSLTTIYFYAFYNTEQLLNTAEVSPDSKLLAAGFDNSCIKLWSLRSKKLKSEPHQVDVSRIHLACDFLEEEDDEDDNLGTEMKVLRGHCGPVYSTRFLADSSGLLSCSEDMSIRYWDLGSFTNTVLYQGHAYPVWDLDISPHSLYFASASHDRTARLWSFDRTYPLRIYAGHLADVDCVKFHPNSNYLATGSTDKTVRLWSTQQGNSVRLFTGHRGPVLSLAFSPNGKYLASAGEDQRLKLWDLASGTLYKELRGHTDNITSLTFSPDSSLVASASMDNSVRVWDIRSSHCSTPADGSSSELVGVYTGQMSNVLSVQFMACNLLLVTGITQENQEH", "length": 591, "header": "tr|F1N575-1|F1N575_BOVIN Isoform 1 of TAF5-like RNA polymerase II p300/CBP-associated factor-associated factor 65 kDa subunit 5L OS=Bos taurus OX=9913 GN=TAF5L PE=3 SV=4 CANONICAL=F1N575-1" }, "isoforms": [ { "isoform_ac": "A0A3Q1LVZ4-1", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1LVZ4/entry", "sequence": { "sequence": "MVMKRVRTEQIQMAVSCYLKRRQYGDADGPVKQGLRLSQSTEEMAASLTDSDSQHSHEVMPLLYPLFVYLHLTLIQNSPKSTVESFYSRFHGMFLQNASQKDVIEQLQTTQTIQDILSNFRLRAFLDNKYVVRLQEDSYNYLLRYLQSDNNTALCRILAWHIHLDVQPAKRTDYQLYTSGGSFRGEGGGLEPADMPAPILQNEAALELLQESIKRVKDGPPSLTTIYFYAFYNTEQLLNTAEVSPDSKLLAAGFDNSCIKLWSLRSKKLKSEPHQVDVSRIHLACDFLEEEDDEDDNLGTEMKVLRGHCGPVYSTRFLADSSGLLSCSEDMSIRYWDLGSFTNTVLYQGHAYPVWDLDISPHSLYFASASHDRTARLWSFDRTYPLRIYAGHLADVDCVKFHPNSNYLATGSTDKTVRLWSTQQGNSVRLFTGHRGPVLSLAFSPNGKYLASAGEDQRLKLWDLASGTLYKELRGHTDNITSLTFSPDSSLVASASMDNSVRVWDIRSSHCSTPADGSSSELVGVYTGQMSNVLSVQFMACNLLLVTGITQENQEH", "length": 556, "header": "tr|A0A3Q1LVZ4-1|F1N575_BOVIN Computationally mapped isoform of TAF5-like RNA polymerase II p300/CBP-associated factor-associated factor 65 kDa subunit 5L OS=Bos taurus OX=9913 GN=TAF5L PE=3 SV=2 CANONICAL=F1N575-1" }, "locus": { "chromosome": "28", "start_pos": 1575717, "end_pos": 1546812, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000069113.2", "url": "https://www.ensembl.org/id/ENSBTAT00000069113.2" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000059530.2", "url": "https://www.ensembl.org/id/ENSBTAP00000059530.2" } ] } }, { "isoform_ac": "A0AAA9S6I5-1", "url": "https://www.uniprot.org/uniprotkb/A0AAA9S6I5/entry", "sequence": { "sequence": "MNCSSPGSSVHGILQVMKRVRTEQIQMAVSCYLKRRQYGDADGPVKQGLRLSQSTEEMAASLTVQSESGCANIVSAAPCQAEPQQYEVQFGRLRNFLTDSDSQHSHEVMPLLYPLFVYLHLTLIQNSPKSTVESFYSRFHGMFLQNASQKDVIEQLQTTQTIQDILSNFRLRAFLDNKYVVRLQEDSYNYLLRYLQSDNNTALCRILAWHIHLDVQPAKRTDYQLYTSGGSFRGEGGGLEPADMPAPILQNEAALELLQESIKRVKDGPPSLTTIYFYAFYNTEQLLNTAEVSPDSKLLAAGFDNSCIKLWSLRSKKLKSEPHQVDVSRIHLACDFLEEEDDEDDNLGTEMKVLRGHCGPVYSTRFLADSSGLLSCSEDMSIRYWDLGSFTNTVLYQGHAYPVWDLDISPHSLYFASASHDRTARLWSFDRTYPLRIYAGHLADVDCVKFHPNSNYLATGSTDKTVRLWSTQQGNSVRLFTGHRGPVLSLAFSPNGKYLASAGEDQRLKLWDLASGTLYKELRGHTDNITSLTFSPDSSLVASASMDNSVRVWDIRSSHCSTPADGSSSELVGVYTGQMSNVLSVQFMACNLLLVTGITQENQEH", "length": 605, "header": "tr|A0AAA9S6I5-1|F1N575_BOVIN Computationally mapped isoform of TAF5-like RNA polymerase II p300/CBP-associated factor-associated factor 65 kDa subunit 5L OS=Bos taurus OX=9913 GN=TAF5L PE=3 SV=1 CANONICAL=F1N575-1" }, "locus": { "chromosome": "28", "start_pos": 1570495, "end_pos": 1546812, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000131456.1", "url": "https://www.ensembl.org/id/ENSBTAT00000131456.1" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000077769.1", "url": "https://www.ensembl.org/id/ENSBTAP00000077769.1" } ] } }, { "isoform_ac": "F1N575-1", "url": "https://www.uniprot.org/uniprotkb/F1N575/entry", "sequence": { "sequence": "MVMKRVRTEQIQMAVSCYLKRRQYGDADGPVKQGLRLSQSTEEMAASLTVQSESGCANIVSAAPCQAEPQQYEVQFGRLRNFLTDSDSQHSHEVMPLLYPLFVYLHLTLIQNSPKSTVESFYSRFHGMFLQNASQKDVIEQLQTTQTIQDILSNFRLRAFLDNKYVVRLQEDSYNYLLRYLQSDNNTALCRILAWHIHLDVQPAKRTDYQLYTSGGSFRGEGGGLEPADMPAPILQNEAALELLQESIKRVKDGPPSLTTIYFYAFYNTEQLLNTAEVSPDSKLLAAGFDNSCIKLWSLRSKKLKSEPHQVDVSRIHLACDFLEEEDDEDDNLGTEMKVLRGHCGPVYSTRFLADSSGLLSCSEDMSIRYWDLGSFTNTVLYQGHAYPVWDLDISPHSLYFASASHDRTARLWSFDRTYPLRIYAGHLADVDCVKFHPNSNYLATGSTDKTVRLWSTQQGNSVRLFTGHRGPVLSLAFSPNGKYLASAGEDQRLKLWDLASGTLYKELRGHTDNITSLTFSPDSSLVASASMDNSVRVWDIRSSHCSTPADGSSSELVGVYTGQMSNVLSVQFMACNLLLVTGITQENQEH", "length": 591, "header": "tr|F1N575-1|F1N575_BOVIN Isoform 1 of TAF5-like RNA polymerase II p300/CBP-associated factor-associated factor 65 kDa subunit 5L OS=Bos taurus OX=9913 GN=TAF5L PE=3 SV=4 CANONICAL=F1N575-1" }, "locus": { "chromosome": "28", "start_pos": 1575717, "end_pos": 1546812, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000048510.5", "url": "https://www.ensembl.org/id/ENSBTAT00000048510.5" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000052514.4", "url": "https://www.ensembl.org/id/ENSBTAP00000052514.4" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [], "orthologs": [], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 3, "go_terms": [ { "name": "nucleus", "id": "GO:0005634", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005634", "evidence": [ { "database": "UniProtKB", "id": "F1N575", "url": "https://www.uniprot.org/uniprotkb/F1N575" } ], "pmid": "" }, { "name": "transcription factor TFTC complex", "id": "GO:0033276", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0033276", "evidence": [ { "database": "UniProtKB", "id": "F1N575", "url": "https://www.uniprot.org/uniprotkb/F1N575" } ], "pmid": "" }, { "name": "SAGA complex", "id": "GO:0000124", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000124", "evidence": [ { "database": "UniProtKB", "id": "F1N575", "url": "https://www.uniprot.org/uniprotkb/F1N575" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 3, "go_terms": [ { "name": "DNA-templated transcription", "id": "GO:0006351", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006351", "evidence": [ { "database": "UniProtKB", "id": "F1N575", "url": "https://www.uniprot.org/uniprotkb/F1N575" } ], "pmid": "" }, { "name": "regulation of gene expression", "id": "GO:0010468", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0010468", "evidence": [ { "database": "UniProtKB", "id": "F1N575", "url": "https://www.uniprot.org/uniprotkb/F1N575" } ], "pmid": "" }, { "name": "regulation of DNA-templated transcription", "id": "GO:0006355", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006355", "evidence": [ { "database": "UniProtKB", "id": "F1N575", "url": "https://www.uniprot.org/uniprotkb/F1N575" } ], "pmid": "" } ] }, { "name": "Molecular Function", "total": 1, "go_terms": [ { "name": "transcription coactivator activity", "id": "GO:0003713", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003713", "evidence": [ { "database": "UniProtKB", "id": "F1N575", "url": "https://www.uniprot.org/uniprotkb/F1N575" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 132, "end_pos": 134, "annotation": "n_glycosylation_sequon" }, { "start_pos": 185, "end_pos": 187, "annotation": "n_glycosylation_sequon" }, { "start_pos": 514, "end_pos": 516, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [ { "pdb_id": "AF-F1N575-F1", "pdb_chain": "global", "start_pos": 1, "end_pos": 591, "overlap": "1.0", "method": "AlphaFold", "type": "alphafold", "resolution": -1.0, "url": "https://data.glygen.org/ln2downloads/pdb/current/AF-F1N575-F1.pdb", "url_external": "https://alphafold.ebi.ac.uk/entry/F1N575" } ], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "F1N575", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1N575" }, { "id": "PF04494", "database": "Pfam", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF04494" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "TFIID subunit TAF5 NTD2", "eco_id": "ECO_0000259", "start_pos": 67, "end_pos": 196, "start_aa": "Ala", "end_aa": "His", "glycosite_overlap": [] } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 132, "end_pos": 134 }, { "start_pos": 185, "end_pos": 187 }, { "start_pos": 514, "end_pos": 516 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ], "tool_support": { "graph_view": "yes" } }, { "uniprot_canonical_ac": "F1N5F9-1", "uniprot_ac": "F1N5F9", "uniprot_id": "F1N5F9_BOVIN", "mass": { "chemical_mass": 74598.0, "monoisotopic_mass": 74598.0 }, "refseq": { "ac": "NP_001192783", "name": "soluble lamin-associated protein of 75 kDa", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001192783" }, "gene_names": [ { "name": "FAM169A", "type": "recommended", "evidence": [ { "id": "F1N5F9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1N5F9" } ] }, { "name": "FAM169A", "type": "synonym", "evidence": [ { "id": "NP_001192783", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001192783" } ] } ], "protein_names": [ { "name": "Family with sequence similarity 169 member A", "type": "synonym", "evidence": [ { "id": "F1N5F9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1N5F9/entry#names_and_taxonomy" } ] }, { "name": "soluble lamin-associated protein of 75 kDa", "type": "synonym", "evidence": [ { "id": "NP_001192783", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001192783" } ] } ], "function": [], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Bos taurus", "taxid": 9913, "evidence": [ { "database": "UniProtKB", "id": "F1N5F9", "url": "https://www.uniprot.org/uniprotkb/F1N5F9" } ], "common_name": "Bovine", "glygen_name": "Bovine", "reference_species": "Bos taurus [9913]" } ], "gene": [ { "name": "FAM169A", "url": "https://www.uniprot.org/uniprotkb/F1N5F9", "locus": { "chromosome": "20", "start_pos": 6738543, "end_pos": 6676080, "strand": "-", "evidence": [ { "database": "Ensembl Gene", "id": "ENSBTAG00000016002", "url": "https://www.ensembl.org/id/ENSBTAG00000016002" } ] } } ], "crossref": [ { "id": "F1N5F9", "url": "https://alphafold.ebi.ac.uk/entry/F1N5F9", "database": "AlphaFoldDB", "categories": [] }, { "id": "ENSBTAG00000016002", "url": "https://bgee.org/?page=gene&gene_id=ENSBTAG00000016002", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "519307", "url": "https://www.ncbi.nlm.nih.gov/gene/519307", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR029625", "url": "https://www.ebi.ac.uk/interpro/entry/IPR029625", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "bta:519307", "url": "https://www.genome.jp/dbget-bin/www_bget?bta:519307", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "DQTHKVL", "url": "https://omabrowser.org/oma/group/DQTHKVL/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "F1N5F9", "url": "https://www.orthodb.org/?gene=F1N5F9", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR22442", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR22442", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR22442:SF3", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR22442:SF3", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "R-BTA-9035034", "url": "https://www.reactome.org/PathwayBrowser/#R-BTA-9035034", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "NP_001192783", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001192783", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A3Q1LX85", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1LX85", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A3Q1LX85-1", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1LX85-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0AAA9TUL0", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TUL0", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0AAA9TUL0-1", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TUL0-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0AAA9TV48", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TV48", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0AAA9TV48-1", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TV48-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "F1N5F9", "url": "https://www.uniprot.org/uniprotkb/F1N5F9", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "F1N5F9-1", "url": "https://www.uniprot.org/uniprotkb/F1N5F9-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MAFPVDMLDNCSHEELENSAEDYMSDLRCGDPENPERFSLLNITIPISLSNVGFVPLYGGDQTQKVLALFAPEDSLTAVALYLADQWWAIDDIVKTSVPSREGLKQVRTLGERVVLYVLNRIIYRKQEMERNEIPFLCHSSTDYAKILWKKGEAIGFYSVKPTGSTCASFLTQSYQLPVLDTMFVRKKYRGKDFGLHMLEDFVDSFTEDALGLRYPLTSLMYIACNQYFEKYPGDHELLWEVEGVGHWYQRIPITRALQRETLKITAISQNEAKRSTSGEYSLASVPEYEARAEDSQSSEMQLTIDSLKDAFASTSEGHDKTPVSTRTRSSHLKRPKIGKRFQDSEFSSSQGEDEKTPQTSPTASVNKLESTARTSESSEEFLEEEPEQSVIEFEDESSDKDVEPAPETQPGLEKQEGEKESALEPMNGEIIDDTLKTSLITEEEDSTSEVLDEELKLQSFNSSEDSPNLAPLVVDSSQPLEGVAQDKTSHATDSETLLDEGPSDDKGHTEEKLPLVSRKKAHFGSSDNVATIPNEDRSDSAFPNSVIAEFSEESIPENVSPNTTASLEDQGEEGVAEPQESSAALPQSSLIEVELEDVPFSQNAGQKNLSEEQSEASSEQLDQLTQSTEKTVDSSSEEIEVEVPVVDRRNLRRKAKGHKGPAKKKAKLT", "length": 670, "header": "tr|F1N5F9-1|F1N5F9_BOVIN Isoform 1 of Family with sequence similarity 169 member A OS=Bos taurus OX=9913 GN=FAM169A PE=4 SV=3 CANONICAL=F1N5F9-1" }, "isoforms": [ { "isoform_ac": "A0A3Q1LX85-1", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1LX85/entry", "sequence": { "sequence": "MVVVVIATQNISLVRMAFPVDMLDNCSHEELENSAEDYMSDLRCGDPENPERFSLLNITIPISLSNVGFVPLYGGDQTQKVLALFAPEDSLTAVALYLADQWWAIDDIVKTSVPSREGLKQVRTLGERVVLYVLNRIIYRKQEMERNEIPFLCHSSTDYAKILWKKGEAIGFYSVKPTGSTCASFLTQSYQLPVLDTMFVRKKYRGKDFGLHMLEDFVDSFTEDALGLRYPLTSLMYIACNQYFEKYPGDHELLWEVEGVGHWYQRIPITRALQRETLKITAISQNEAKRSTSGEYSLASVPEYEARAEDSQSSEMQLTIDSLKDAFASTSEGHDKTPVSTRTRSSHLKRPKIGKRFQDSEFSSSQGEDEKTPQTSPTASVNKLESTARTSESSEEFLEEEPEQSVIEFEDESSDKDVEPAPETQPGLEKQEGEKESALEPMNGEIIDDTLKTSLITEEEDSTSEVLDEELKLQSFNSSEDSPNLAPLVVDSSQPLEGVAQDKTSHATDSETLLDEGPSDDKGHTEEKLPLVSRKKAHFGSSDNVATIPNEDRSDSAFPNSVIAEFSEESIPENVSPNTTASLEDQGEEGVAEPQESSAALPQSSLIEVELEDVPFSQNAGQKNLSEEQSEASSEQLDQLTQSTEKTVDSSSEEIEVEVPVVDRRNLRRKAKGHKGPAKKKAKLT", "length": 685, "header": "tr|A0A3Q1LX85-1|F1N5F9_BOVIN Computationally mapped isoform of Family with sequence similarity 169 member A OS=Bos taurus OX=9913 GN=FAM169A PE=4 SV=1 CANONICAL=F1N5F9-1" }, "locus": { "chromosome": "20", "start_pos": 6738264, "end_pos": 6684476, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000071107.3", "url": "https://www.ensembl.org/id/ENSBTAT00000071107.3" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000065356.2", "url": "https://www.ensembl.org/id/ENSBTAP00000065356.2" } ] } }, { "isoform_ac": "A0AAA9TUL0-1", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TUL0/entry", "sequence": { "sequence": "MAFPVDMLDNCSHEELENSAEDYMSDLRCGDPENPERFSLLNITIPISLSNVGFVPLYGGDQTQKVLALFAPEDSLTAVALYLADQWWAIDDIVKTSVPSREGLKQVRTLGERVVLYVLNRIIYRKQEMERNEIPFLCHSSTDYAKILWKKGEAIGFYSVKPTACNQYFEKYPGDHELLWEVEGVGHWYQRIPITRALQRETLKITAISQNEAKRSTSGEYSLASVPEYEARAEDSQSSEMQLTIDSLKDAFASTSEGHDKTPVSTRTRSSHLKRPKIGKRFQDSEFSSSQGEDEKTPQTSPTASVNKLESTARTSESSEEFLEEEPEQSVIEFEDESSDKDVEPAPETQPGLEKQEGEKESALEPMNGEIIDDTLKTSLITEEEDSTSEVLDEELKLQSFNSSEDSPNLAPLVVDSSQPLEGVAQDKTSHATDSETLLDEGPSDDKGHTEEKLPLVSRKKAHFGSSDNVATIPNEDRSDSAFPNSVIAEFSEESIPENVSPNTTASLEDQGEEGVAEPQESSAALPQSSLIEVELEDVPFSQNAGQKNLSEEQSEASSEQLDQLTQSTEKTVDSSSEEIEVEVPVVDRRNLRRKAKGHKGPAKKKAKLT", "length": 610, "header": "tr|A0AAA9TUL0-1|F1N5F9_BOVIN Computationally mapped isoform of Family with sequence similarity 169 member A OS=Bos taurus OX=9913 GN=FAM169A PE=4 SV=1 CANONICAL=F1N5F9-1" }, "locus": { "chromosome": "20", "start_pos": 6738264, "end_pos": 6696260, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000134259.2", "url": "https://www.ensembl.org/id/ENSBTAT00000134259.2" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000100807.1", "url": "https://www.ensembl.org/id/ENSBTAP00000100807.1" } ] } }, { "isoform_ac": "A0AAA9TV48-1", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TV48/entry", "sequence": { "sequence": "MRMAFPVDMLDNCSHEELENSAEDYMSDLRCGDPENPERFSLLNITIPISLSNVGFVPLYGGDQTQKVLALFAPEDSLTAVALYLADQWWAIDDIVKTSVPSREGLKQVRTLGERVVLYVLNRIIYRKQEMERNEIPFLCHSSTDYAKILWKKGEAIGFYSVKPTGSTCASFLTQSYQLPVLDTMFVRKKYRGKDFGLHMLEDFVDSFTEDALGLRYPLTSLMYIACNQYFEKYPGDHELLWEVEGVGHWYQRIPITRALQRETLKITAISQNEAKRSTSGEYSLASVPEYEARAEDSQSSEMQLTIDSLKDAFASTSEGHDKTPVSTRTRSSHLKRPKIGKRFQDSEFSSSQGEDEKTPQTSPTASVNKLESTARTSESSEEFLEEEPEQSVIEFEDESSDKDVEPAPETQPGLEKQEGEKESALEPMNGEIIDDTLKTSLITEEEDSTSEVLDEELKLQSFNSSEDSPNLAPLVVDSSQPLEGVAQDKTSHATDSETLLDEGPSDDKGHTEEKLPLVSRKKAHFGSSDNVATIPNEDRSDSAFPNSVIAEFSEESIPENVSPNTTASLEDQGEEGVAEPQESSAALPQSSLIEVELEDVPFSQNAGQKNLSEEQSEASSEQLDQLTQSTEKTVDSSSEEIEVEVPVVDRRNLRRKAKGHKGPAKKKAKLT", "length": 672, "header": "tr|A0AAA9TV48-1|F1N5F9_BOVIN Computationally mapped isoform of Family with sequence similarity 169 member A OS=Bos taurus OX=9913 GN=FAM169A PE=4 SV=1 CANONICAL=F1N5F9-1" }, "locus": { "chromosome": "20", "start_pos": 6738264, "end_pos": 6676279, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000135415.2", "url": "https://www.ensembl.org/id/ENSBTAT00000135415.2" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000101003.1", "url": "https://www.ensembl.org/id/ENSBTAP00000101003.1" } ] } }, { "isoform_ac": "F1N5F9-1", "url": "https://www.uniprot.org/uniprotkb/F1N5F9/entry", "sequence": { "sequence": "MAFPVDMLDNCSHEELENSAEDYMSDLRCGDPENPERFSLLNITIPISLSNVGFVPLYGGDQTQKVLALFAPEDSLTAVALYLADQWWAIDDIVKTSVPSREGLKQVRTLGERVVLYVLNRIIYRKQEMERNEIPFLCHSSTDYAKILWKKGEAIGFYSVKPTGSTCASFLTQSYQLPVLDTMFVRKKYRGKDFGLHMLEDFVDSFTEDALGLRYPLTSLMYIACNQYFEKYPGDHELLWEVEGVGHWYQRIPITRALQRETLKITAISQNEAKRSTSGEYSLASVPEYEARAEDSQSSEMQLTIDSLKDAFASTSEGHDKTPVSTRTRSSHLKRPKIGKRFQDSEFSSSQGEDEKTPQTSPTASVNKLESTARTSESSEEFLEEEPEQSVIEFEDESSDKDVEPAPETQPGLEKQEGEKESALEPMNGEIIDDTLKTSLITEEEDSTSEVLDEELKLQSFNSSEDSPNLAPLVVDSSQPLEGVAQDKTSHATDSETLLDEGPSDDKGHTEEKLPLVSRKKAHFGSSDNVATIPNEDRSDSAFPNSVIAEFSEESIPENVSPNTTASLEDQGEEGVAEPQESSAALPQSSLIEVELEDVPFSQNAGQKNLSEEQSEASSEQLDQLTQSTEKTVDSSSEEIEVEVPVVDRRNLRRKAKGHKGPAKKKAKLT", "length": 670, "header": "tr|F1N5F9-1|F1N5F9_BOVIN Isoform 1 of Family with sequence similarity 169 member A OS=Bos taurus OX=9913 GN=FAM169A PE=4 SV=3 CANONICAL=F1N5F9-1" }, "locus": { "chromosome": "20", "start_pos": 6738264, "end_pos": 6696260, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000021301.7", "url": "https://www.ensembl.org/id/ENSBTAT00000021301.7" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000021301.6", "url": "https://www.ensembl.org/id/ENSBTAP00000021301.6" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [ { "id": "bta:519307", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?bta:519307", "resource": "KEGG Pathway" }, { "id": "R-BTA-9035034", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-BTA-9035034", "resource": "Reactome", "description": "RHOF GTPase cycle" } ], "orthologs": [ { "uniprot_canonical_ac": "A0A8I6G2A6-1", "protein_name": "Family with sequence similarity 169, member A", "gene_name": "Fam169a", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MQRMAFPVDLLDNCTHEELENSAEDYLSNLRCGDPENPECFSILNFTIPVSLSNVGFVPLYGGNQTQKILALFAPEDSLTAVALYLVGQWWAIDDLVKTSEPSREGLKQVSTLGERVVLYVLNRIIYRKQEMERNEIPFLCHSSTDYAKILWKKGEAIGFYSVKPTGSLCASFLTQNYQLPVLDTMFIRKKYRGKDLGLHMLEDFVDSFTEDALGLRYPLSSLMYTASKQYFEKYPGDHELLWEVEGVGHWHQRIPITRALQREAVNVTEISQYEAKRPVSGEYGPAAVPECEPGLGERQCRELQIHSLKDAFASTSEGPEKTPVSTRTRSSHLKRPKIGKRFQESEFSSSQGEDENSAQTSPMASVNKIEYAARTSESSEEVPEEEPEKRVVECEDGSSDKDARPALETQPRLQKQDGDRDSALEPVNGEVTDAALKTSLAAEENDSSSEGPEEEIPPLTSSGETGPPVPRAAESSKAPEATLDQTSPVTDAEMLTDEGPSNDKGHTEENLSPVSKKKTILGSSDNVATLSNEEKSDGDFPNSVVAEFPEEPVSENVSPNTTSSVEDQGEEGVPEAQEPSATQSSLIEVELEDVPFPQNAGQKSQSEEQSEASSEQLEQYAQSAEKAVDSSSEEIEVEVPVVDRRSLRRKAKGHKGPGKKKAKMT", "length": 666 }, "evidence": [ { "id": "F1N5F9", "url": "https://omabrowser.org/oma/group/F1N5F9/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "Q5XG69-1", "protein_name": "Soluble lamin-associated protein of 75 kDa", "gene_name": "Fam169a", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MAFPVDLLDNCTHEELENSSEDYLSSLRCGDPEHPECFSSLNITIPVSLSNVGFVPLYGGNQTQKILALFAPEDSLTAVALYLVGQWWAIDDIVKTSEPSREGLKQVSTLGERVVLYVLNRIIYRKQEMERNEIPFLCHSSTDYAKILWKKGEAVGFYSVKPTGSLCASFLTQNYQLPVLDTMFIRKKYRGKDLGLHMLEDFVDSFTEDALGLRYPLSSLMYTASKQYFEKYPGDHELLWEVEGVGHWHQRVPVTRALQREAIKATDVSQYEATRPVSGEYGLAAVPEHEPGLDDTQSSELQIHSLKDAFASTSEGPEKTPVSTRTRSSHLKRPKIGKHFQDSEFSSSQGEDENVAKTSPTASVNKIEYAARTSESSEEFLEEEPEQGVIDFEDESGDKDAQPALETQPRLQKQDGDKDSALEPVNGEVMDAALKPSLTTEDEDSTSEGLEEDLKVPPFNSSGEPGNPVPLVAESSKVPEATLAKTSPDTDSEMLIDQSPSDDKGHTEENLSPVSKKKTLLGSSDNVATVSNIEKSDGNFPNSVVPEFPEEPVSQNLSPNTTSSVEDQGEEGAPEAQEPSATQSSLIEVELEDAPFPQNAGQKSQSEEQSEASSEHLEQFTQSAEKAVDSSSEEIEVEVPVVDRRNLRRKAKGHKGPGKKKAKLT", "length": 665 }, "evidence": [ { "id": "F1N5F9", "url": "https://omabrowser.org/oma/group/F1N5F9/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q9Y6X4-1", "protein_name": "Soluble lamin-associated protein of 75 kDa", "gene_name": "FAM169A", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MAFPVDMLENCSHEELENSAEDYMSDLRCGDPENPECFSLLNITIPISLSNVGFVPLYGGDQTQKILALFAPEDSLTAVALYLADQWWAIDDIVKTSVPSREGLKQVSTLGERVVLYVLNRIIYRKQEMERNEIPFLCHSSTDYAKILWKKGEAIGFYSVKPTGSICASFLTQSYQLPVLDTMFLRKKYRGKDFGLHMLEDFVDSFTEDALGLRYPLSSLMYTACKQYFEKYPGDHELLWEVEGVGHWYQRIPVTRALQREALKILALSQNEPKRPMSGEYGPASVPEYEARTEDNQSSEMQLTIDSLKDAFASTSEGHDKTSVSTHTRSGNLKRPKIGKRFQDSEFSSSQGEDEKTSQTSLTASINKLESTARPSESSEEFLEEEPEQRGIEFEDESSDRDARPALETQPQQEKQDGEKESELEPMNGEIMDDSLKTSLITEEEDSTSEVLDEELKLQPFNSSEDSTNLVPLVVESSKPPEVDAPDKTPRIPDSEMLMDEGTSDEKGHMEEKLSLLPRKKAHLGSSDNVATMSNEERSDGGFPNSVIAEFSEEPVSENLSPNTTSSLEDQGEEGVSEPQETSTALPQSSLIEVELEDVPFSQNAGQKNQSEEQSEASSEQLDQFTQSAEKAVDSSSEEIEVEVPVVDRRNLRRKAKGHKGPAKKKAKLT", "length": 670 }, "evidence": [ { "id": "F1N5F9", "url": "https://omabrowser.org/oma/group/F1N5F9/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" } ], "go_annotation": {}, "pro_annotation": [], "site_annotation": [ { "start_pos": 10, "end_pos": 12, "annotation": "n_glycosylation_sequon" }, { "start_pos": 42, "end_pos": 44, "annotation": "n_glycosylation_sequon" }, { "start_pos": 462, "end_pos": 464, "annotation": "n_glycosylation_sequon" }, { "start_pos": 559, "end_pos": 561, "annotation": "n_glycosylation_sequon" }, { "start_pos": 563, "end_pos": 565, "annotation": "n_glycosylation_sequon" }, { "start_pos": 609, "end_pos": 611, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [ { "pdb_id": "AF-F1N5F9-F1", "pdb_chain": "global", "start_pos": 1, "end_pos": 670, "overlap": "1.0", "method": "AlphaFold", "type": "alphafold", "resolution": -1.0, "url": "https://data.glygen.org/ln2downloads/pdb/current/AF-F1N5F9-F1.pdb", "url_external": "https://alphafold.ebi.ac.uk/entry/F1N5F9" } ], "lectin_list": [], "domain_list": [], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" }, { "name": "homologset.oma", "label": "OMA Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 10, "end_pos": 12 }, { "start_pos": 42, "end_pos": 44 }, { "start_pos": 462, "end_pos": 464 }, { "start_pos": 559, "end_pos": 561 }, { "start_pos": 563, "end_pos": 565 }, { "start_pos": 609, "end_pos": 611 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ], "tool_support": { "graph_view": "yes" } }, { "uniprot_canonical_ac": "F6QTJ5-1", "uniprot_ac": "F6QTJ5", "uniprot_id": "F6QTJ5_BOVIN", "mass": { "chemical_mass": 47041.0, "monoisotopic_mass": 47041.0 }, "refseq": { "ac": "XP_005217384", "name": "potassium channel subfamily K member 2 isoform X1", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_005217384" }, "gene_names": [ { "name": "KCNK2", "type": "recommended", "evidence": [ { "id": "F6QTJ5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F6QTJ5" } ] }, { "name": "KCNK2", "type": "synonym", "evidence": [ { "id": "XP_005217384", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_005217384" } ] } ], "protein_names": [ { "name": "Potassium two pore domain channel subfamily K member 2", "type": "synonym", "evidence": [ { "id": "F6QTJ5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F6QTJ5/entry#names_and_taxonomy" } ] }, { "name": "potassium channel subfamily K member 2 isoform X1", "type": "synonym", "evidence": [ { "id": "XP_005217384", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_005217384" } ] } ], "function": [], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Bos taurus", "taxid": 9913, "evidence": [ { "database": "UniProtKB", "id": "F6QTJ5", "url": "https://www.uniprot.org/uniprotkb/F6QTJ5" } ], "common_name": "Bovine", "glygen_name": "Bovine", "reference_species": "Bos taurus [9913]" } ], "gene": [ { "name": "KCNK2", "url": "https://www.uniprot.org/uniprotkb/F6QTJ5", "locus": { "chromosome": "16", "start_pos": 68370670, "end_pos": 68626190, "strand": "+", "evidence": [ { "database": "Ensembl Gene", "id": "ENSBTAG00000004407", "url": "https://www.ensembl.org/id/ENSBTAG00000004407" } ] } } ], "crossref": [ { "id": "F6QTJ5", "url": "https://alphafold.ebi.ac.uk/entry/F6QTJ5", "database": "AlphaFoldDB", "categories": [] }, { "id": "ENSBTAG00000004407", "url": "https://bgee.org/?page=gene&gene_id=ENSBTAG00000004407", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "282590", "url": "https://www.ncbi.nlm.nih.gov/gene/282590", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR003280", "url": "https://www.ebi.ac.uk/interpro/entry/IPR003280", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR003976", "url": "https://www.ebi.ac.uk/interpro/entry/IPR003976", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR013099", "url": "https://www.ebi.ac.uk/interpro/entry/IPR013099", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "ANLCEDR", "url": "https://omabrowser.org/oma/group/ANLCEDR/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "A0A3Q1LQ50", "url": "https://www.orthodb.org/?gene=A0A3Q1LQ50", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A3Q1LZV4", "url": "https://www.orthodb.org/?gene=A0A3Q1LZV4", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A3Q1NJL0", "url": "https://www.orthodb.org/?gene=A0A3Q1NJL0", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR11003", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR11003", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR11003:SF21", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR11003:SF21", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF07885", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF07885", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "R-BTA-1299503", "url": "https://www.reactome.org/PathwayBrowser/#R-BTA-1299503", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "R-BTA-5576886", "url": "https://www.reactome.org/PathwayBrowser/#R-BTA-5576886", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "XP_005217384", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_005217384", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "29463", "url": "https://www.rhea-db.org/rhea/29463", "database": "Rhea", "categories": [ "Enzyme and Pathway" ] }, { "id": "78547", "url": "https://www.rhea-db.org/rhea/78547", "database": "Rhea", "categories": [ "Enzyme and Pathway" ] }, { "id": "78555", "url": "https://www.rhea-db.org/rhea/78555", "database": "Rhea", "categories": [ "Enzyme and Pathway" ] }, { "id": "A0A3Q1LQ50", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1LQ50", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A3Q1LQ50-1", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1LQ50-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A3Q1LZV4", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1LZV4", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A3Q1LZV4-1", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1LZV4-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A3Q1NJL0", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1NJL0", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A3Q1NJL0-1", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1NJL0-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "F6QTJ5", "url": "https://www.uniprot.org/uniprotkb/F6QTJ5", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "F6QTJ5-1", "url": "https://www.uniprot.org/uniprotkb/F6QTJ5-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MLPSASRERTGYRAGVAAPDLLDPKSAAQNSKPRLSFSTKPTVLASRVESDTTINVMKWKTVSTIFLVVVLYLIIGATVFKALEQPHEISQRTTIVIQKQTFISQHACVNSTELDELIQQIVAAINAGIIPLGNTSNQISHWDLGSSFFFAGTVITTIGFGNISPRTEGGKIFCIIYALLGIPLFGFLLAGVGDQLGTIFGKGIAKVEDTFIKWNVSQTKIRIISTIIFILFGCVLFVALPAIIFKHIEGWSALDAIYFVVITLTTIGFGDYVAGGSDIEYLDFYKPVVWFWILVGLAYFAAVLSMIGDWLRVISKKTKEEVGEFRAHAAEWTANVTAEFKETRRRLSVEIYDKFQRATSIKRKLSAELAGNHNQELTPCRRTLSVNHLASERDVLPSLLKTESIYLNGLTPHCAGEEIAVIENIK", "length": 426, "header": "tr|F6QTJ5-1|F6QTJ5_BOVIN Isoform 1 of Potassium two pore domain channel subfamily K member 2 OS=Bos taurus OX=9913 GN=KCNK2 PE=3 SV=1 CANONICAL=F6QTJ5-1" }, "isoforms": [ { "isoform_ac": "A0A3Q1LQ50-1", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1LQ50/entry", "sequence": { "sequence": "MPYCAVAAPDLLDPKSAAQNSKPRLSFSTKPTVLASRVESDTTINVMKWKTVSTIFLVVVLYLIIGATVFKALEQPHEISQRTTIVIQKQTFISQHACVNSTELDELIQQIVAAINAGIIPLGNTSNQISHWDLGSSFFFAGTVITTIGFGNISPRTEGGKIFCIIYALLGIPLFGFLLAGVGDQLGTIFGKGIAKVEDTFIKWNVSQTKIRIISTIIFILFGCVLFVALPAIIFKHIEGWSALDAIYFVVITLTTIGFGDYVAGGSDIEYLDFYKPVVWFWILVGLAYFAAVLSMIGDWLRVISKKTKEEVGEFRAHAAEWTANVTAEFKETRRRLSVEIYDKFQRATSIKRKLSAELAGNHNQELTPCRRTLSVNHLASERDVLPSLLKTESIYLNGLTPHCAGEEIAVIENIK", "length": 416, "header": "tr|A0A3Q1LQ50-1|A0A3Q1LQ50_BOVIN Computationally mapped isoform of Potassium two pore domain channel subfamily K member 2 OS=Bos taurus OX=9913 GN=KCNK2 PE=3 SV=2 CANONICAL=F6QTJ5-1" }, "locus": { "chromosome": "16", "start_pos": 68623136, "end_pos": 68372981, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000074252.2", "url": "https://www.ensembl.org/id/ENSBTAT00000074252.2" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000059165.2", "url": "https://www.ensembl.org/id/ENSBTAP00000059165.2" } ] } }, { "isoform_ac": "A0A3Q1LZV4-1", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1LZV4/entry", "sequence": { "sequence": "MMNPRAKRNFCLAAPDLLDPKSAAQNSKPRLSFSTKPTVLASRVESDTTINVMKWKTVSTIFLVVVLYLIIGATVFKALEQPHEISQRTTIVIQKQTFISQHACVNSTELDELIQQIVAAINAGIIPLGNTSNQISHWDLGSSFFFAGTVITTIGFGNISPRTEGGKIFCIIYALLGIPLFGFLLAGVGDQLGTIFGKGIAKVEDTFIKWNVSQTKIRIISTIIFILFGCVLFVALPAIIFKHIEGWSALDAIYFVVITLTTIGFGDYVAGGSDIEYLDFYKPVVWFWILVGLAYFAAVLSMIGDWLRVISKKTKEEVGEFRAHAAEWTANVTAEFKETRRRLSVEIYDKFQRATSIKRKLSAELAGNHNQELTPCRRTLSVNHLASERDVLPSLLKTESIYLNGLTPHCAGEEIAVIENIK", "length": 422, "header": "tr|A0A3Q1LZV4-1|F6QTJ5_BOVIN Computationally mapped isoform of Potassium two pore domain channel subfamily K member 2 OS=Bos taurus OX=9913 GN=KCNK2 PE=3 SV=1 CANONICAL=F6QTJ5-1" }, "locus": { "chromosome": "16", "start_pos": 68594740, "end_pos": 68372981, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000078419.2", "url": "https://www.ensembl.org/id/ENSBTAT00000078419.2" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000062878.1", "url": "https://www.ensembl.org/id/ENSBTAP00000062878.1" } ] } }, { "isoform_ac": "A0A3Q1NJL0-1", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1NJL0/entry", "sequence": { "sequence": "MEERRVKEGVAAPDLLDPKSAAQNSKPRLSFSTKPTVLASRVESDTTINVMKWKTVSTIFLVVVLYLIIGATVFKALEQPHEISQRTTIVIQKQTFISQHACVNSTELDELIQQIVAAINAGIIPLGNTSNQISHWDLGSSFFFAGTVITTIGFGNISPRTEGGKIFCIIYALLGIPLFGFLLAGVGDQLGTIFGKGIAKVEDTFIKWNVSQTKIRIISTIIFILFGCVLFVALPAIIFKHIEGWSALDAIYFVVITLTTIGFGDYVAGGSDIEYLDFYKPVVWFWILVGLAYFAAVLSMIGDWLRVISKKTKEEVGEFRAHAAEWTANVTAEFKETRRRLSVEIYDKFQRATSIKRKLSAELAGNHNQELTPCRRTLSVNHLASERDVLPSLLKTESIYLNGLTPHCAGEEIAVIENIK", "length": 420, "header": "tr|A0A3Q1NJL0-1|F6QTJ5_BOVIN Computationally mapped isoform of Potassium two pore domain channel subfamily K member 2 OS=Bos taurus OX=9913 GN=KCNK2 PE=3 SV=2 CANONICAL=F6QTJ5-1" }, "locus": { "chromosome": "16", "start_pos": 68608629, "end_pos": 68372981, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000074057.3", "url": "https://www.ensembl.org/id/ENSBTAT00000074057.3" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000072372.2", "url": "https://www.ensembl.org/id/ENSBTAP00000072372.2" } ] } }, { "isoform_ac": "F6QTJ5-1", "url": "https://www.uniprot.org/uniprotkb/F6QTJ5/entry", "sequence": { "sequence": "MLPSASRERTGYRAGVAAPDLLDPKSAAQNSKPRLSFSTKPTVLASRVESDTTINVMKWKTVSTIFLVVVLYLIIGATVFKALEQPHEISQRTTIVIQKQTFISQHACVNSTELDELIQQIVAAINAGIIPLGNTSNQISHWDLGSSFFFAGTVITTIGFGNISPRTEGGKIFCIIYALLGIPLFGFLLAGVGDQLGTIFGKGIAKVEDTFIKWNVSQTKIRIISTIIFILFGCVLFVALPAIIFKHIEGWSALDAIYFVVITLTTIGFGDYVAGGSDIEYLDFYKPVVWFWILVGLAYFAAVLSMIGDWLRVISKKTKEEVGEFRAHAAEWTANVTAEFKETRRRLSVEIYDKFQRATSIKRKLSAELAGNHNQELTPCRRTLSVNHLASERDVLPSLLKTESIYLNGLTPHCAGEEIAVIENIK", "length": 426, "header": "tr|F6QTJ5-1|F6QTJ5_BOVIN Isoform 1 of Potassium two pore domain channel subfamily K member 2 OS=Bos taurus OX=9913 GN=KCNK2 PE=3 SV=1 CANONICAL=F6QTJ5-1" }, "locus": { "chromosome": "16", "start_pos": 68507282, "end_pos": 68372981, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000005781.5", "url": "https://www.ensembl.org/id/ENSBTAT00000005781.5" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000005781.4", "url": "https://www.ensembl.org/id/ENSBTAP00000005781.4" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [ { "id": "R-BTA-1299503", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-BTA-1299503", "resource": "Reactome", "description": "TWIK related potassium channel (TREK)" }, { "id": "R-BTA-5576886", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-BTA-5576886", "resource": "Reactome", "description": "Phase 4 - resting membrane potential" } ], "orthologs": [ { "uniprot_canonical_ac": "A0A8V0Z908-1", "protein_name": "Potassium two pore domain channel subfamily K member 2", "gene_name": "KCNK2", "tax_id": 9031, "organism": "Gallus gallus", "sequence": { "sequence": "MRNPQARHNFYLAAPDLLDPKSATQNSKPRLSFSTKPTVLSSREESDSAINVMKWKTVSTIFLVVVVYLIIGATVFKALEQPHETSQRATIVIQKQTFVSQHSCVNATELDELIQQVVAAINAGIIPLGNTSTQISHWDLGSSFFFAGTVITTIGFGNISPRTQGGKIFCIIYALLGIPLFGFLLAGVGDQLGTIFGKGIAKVEDTFVKWNVSQTKIRIISTIIFILFGCVLFVALPAVIFKHIEGWSTLDAIYFVVITLTTIGFGDYVAGGSDIEYLDFYKPVVWFWILVGLAYFAAVLSMIGDWLRVISKKTKEEVGEFRAHAAEWTANVTAEFKETRRRLSVEIYDKFQRATSIKRKLSAELAVNHNQDLTPCKRTLSVNHLTSEKDLLPALTKTDSIYMNGLTPHCAAEEIAVIENIK", "length": 422 }, "evidence": [ { "id": "F6QTJ5", "url": "https://omabrowser.org/oma/group/F6QTJ5/", "database": "OMA" } ], "glygen_name": "Chicken", "common_name": "Chicken" }, { "uniprot_canonical_ac": "O95069-1", "protein_name": "Potassium channel subfamily K member 2", "gene_name": "KCNK2", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MLPSASRERPGYRAGVAAPDLLDPKSAAQNSKPRLSFSTKPTVLASRVESDTTINVMKWKTVSTIFLVVVLYLIIGATVFKALEQPHEISQRTTIVIQKQTFISQHSCVNSTELDELIQQIVAAINAGIIPLGNTSNQISHWDLGSSFFFAGTVITTIGFGNISPRTEGGKIFCIIYALLGIPLFGFLLAGVGDQLGTIFGKGIAKVEDTFIKWNVSQTKIRIISTIIFILFGCVLFVALPAIIFKHIEGWSALDAIYFVVITLTTIGFGDYVAGGSDIEYLDFYKPVVWFWILVGLAYFAAVLSMIGDWLRVISKKTKEEVGEFRAHAAEWTANVTAEFKETRRRLSVEIYDKFQRATSIKRKLSAELAGNHNQELTPCRRTLSVNHLTSERDVLPPLLKTESIYLNGLTPHCAGEEIAVIENIK", "length": 426 }, "evidence": [ { "id": "F6QTJ5", "url": "https://omabrowser.org/oma/group/F6QTJ5/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "P97438-1", "protein_name": "Potassium channel subfamily K member 2", "gene_name": "Kcnk2", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MLASASRERPGYTAGVAAPDLLDPKSAAQNSKPRLSFSSKPTVLASRVESDSAINVMKWKTVSTIFLVVVLYLIIGATVFKALEQPQEISQRTTIVIQKQTFIAQHACVNSTELDELIQQIVAAINAGIIPLGNSSNQVSHWDLGSSFFFAGTVITTIGFGNISPRTEGGKIFCIIYALLGIPLFGFLLAGVGDQLGTIFGKGIAKVEDTFIKWNVSQTKIRIISTIIFILFGCVLFVALPAVIFKHIEGWSALDAIYFVVITLTTIGFGDYVAGGSDIEYLDFYKPVVWFWILVGLAYFAAVLSMIGDWLRVISKKTKEEVGEFRAHAAEWTANVTAEFKETRRRLSVEIYDKFQRATSVKRKLSAELAGNHNQELTPCRRTLSVNHLTSEREVLPPLLKAESIYLNGLTPHCAGEDIAVIENMK", "length": 426 }, "evidence": [ { "id": "F6QTJ5", "url": "https://omabrowser.org/oma/group/F6QTJ5/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q920B6-1", "protein_name": "Potassium channel subfamily K member 2", "gene_name": "Kcnk2", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MLASASRERPGYTAGVAAPDLLDPKSAAQNSKPRLSFSAKPTVLASRVESDSAINVMKWKTVSTIFLVVVLYLIIGATVFKALEQPQEISQRTTIVIQKQNFIAQHACVNSTELDELIQQIVTAINAGIIPLGNNSNQVSHWDLGSSFFFAGTVITTIGFGNISPRTEGGKIFCIIYALLGIPLFGFLLAGVGDQLGTIFGKGIAKVEDTFIKWNVSQTKIRIISTIIFILFGCVLFVALPAVIFKHIEGWSALDAIYFVVITLTTIGFGDYVAGGSDIEYLDFYKPVVWFWILVGLAYFAAVLSMIGDWLRVISKKTKEEVGEFRAHAAEWTANVTAEFKETRRRLSVEIYDKFQRATSVKRKLSAELAGNHNQELTPCRRTLSVNHLTSEREVLPPLLKAESIYLNGLTPHCAAEDIAVIENMK", "length": 426 }, "evidence": [ { "id": "F6QTJ5", "url": "https://omabrowser.org/oma/group/F6QTJ5/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" } ], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 1, "go_terms": [ { "name": "plasma membrane", "id": "GO:0005886", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005886", "evidence": [ { "database": "UniProtKB", "id": "F6QTJ5", "url": "https://www.uniprot.org/uniprotkb/F6QTJ5" } ], "pmid": "" } ] }, { "name": "Molecular Function", "total": 3, "go_terms": [ { "name": "potassium channel activity", "id": "GO:0005267", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005267", "evidence": [ { "database": "UniProtKB", "id": "F6QTJ5", "url": "https://www.uniprot.org/uniprotkb/F6QTJ5" } ], "pmid": "" }, { "name": "outward rectifier potassium channel activity", "id": "GO:0015271", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0015271", "evidence": [ { "database": "UniProtKB", "id": "F6QTJ5", "url": "https://www.uniprot.org/uniprotkb/F6QTJ5" } ], "pmid": "" }, { "name": "potassium ion leak channel activity", "id": "GO:0022841", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0022841", "evidence": [ { "database": "UniProtKB", "id": "F6QTJ5", "url": "https://www.uniprot.org/uniprotkb/F6QTJ5" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 1, "go_terms": [ { "name": "potassium ion transmembrane transport", "id": "GO:0071805", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0071805", "evidence": [ { "database": "UniProtKB", "id": "F6QTJ5", "url": "https://www.uniprot.org/uniprotkb/F6QTJ5" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 110, "end_pos": 112, "annotation": "n_glycosylation_sequon" }, { "start_pos": 134, "end_pos": 136, "annotation": "n_glycosylation_sequon" }, { "start_pos": 162, "end_pos": 164, "annotation": "n_glycosylation_sequon" }, { "start_pos": 215, "end_pos": 217, "annotation": "n_glycosylation_sequon" }, { "start_pos": 335, "end_pos": 337, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [ { "id": "29463", "name": "", "equation": "K(+)(in) = K(+)(out)", "summary": "", "cellular_location": "", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [ "P35526-1" ], "evidence": [ { "id": "29463", "database": "Rhea", "url": "https://www.rhea-db.org/rhea/29463" } ] }, { "id": "78547", "name": "", "equation": "Rb(+)(in) = Rb(+)(out)", "summary": "", "cellular_location": "", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [], "evidence": [ { "id": "78547", "database": "Rhea", "url": "https://www.rhea-db.org/rhea/78547" } ] }, { "id": "78555", "name": "", "equation": "Cs(+)(in) = Cs(+)(out)", "summary": "", "cellular_location": "", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [], "evidence": [ { "id": "78555", "database": "Rhea", "url": "https://www.rhea-db.org/rhea/78555" } ] } ], "reaction_participants": [], "reaction_enzymes": [ { "uniprot_ac": "P35526", "gene_name": "CLIC5", "activity": [ { "ec_number": "1.8.-.-", "activity": "", "evidence": [ { "id": "P35526", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P35526" } ] } ] } ], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "F6QTJ5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F6QTJ5" }, { "id": "PF07885", "database": "Pfam", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF07885" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "Potassium channel", "eco_id": "ECO_0000259", "start_pos": 137, "end_pos": 195, "start_aa": "Asn", "end_aa": "Gln", "glycosite_overlap": [] } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" }, { "name": "homologset.oma", "label": "OMA Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 110, "end_pos": 112 }, { "start_pos": 134, "end_pos": 136 }, { "start_pos": 162, "end_pos": 164 }, { "start_pos": 215, "end_pos": 217 }, { "start_pos": 335, "end_pos": 337 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ], "tool_support": { "graph_view": "yes" } }, { "uniprot_canonical_ac": "F1N726-1", "uniprot_ac": "F1N726", "uniprot_id": "F1N726_BOVIN", "mass": { "chemical_mass": 59249.0, "monoisotopic_mass": 59249.0 }, "refseq": { "ac": "NP_001069418", "name": "pancreatic secretory granule membrane major glycoprotein GP2 precursor", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001069418" }, "gene_names": [ { "name": "GP2", "type": "recommended", "evidence": [ { "id": "F1N726", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1N726" } ] }, { "name": "GP2", "type": "synonym", "evidence": [ { "id": "NP_001069418", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001069418" } ] } ], "protein_names": [ { "name": "Glycoprotein 2", "type": "synonym", "evidence": [ { "id": "F1N726", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1N726/entry#names_and_taxonomy" } ] }, { "name": "glycoprotein 2 (zymogen granule membrane)", "type": "synonym", "evidence": [ { "id": "NP_001069418", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001069418" } ] }, { "name": "pancreatic secretory granule membrane major glycoprotein GP2 precursor", "type": "synonym", "evidence": [ { "id": "NP_001069418", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001069418" } ] }, { "name": "zymogen granule membrane glycoprotein 2", "type": "synonym", "evidence": [ { "id": "NP_001069418", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001069418" } ] } ], "function": [], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Bos taurus", "taxid": 9913, "evidence": [ { "database": "UniProtKB", "id": "F1N726", "url": "https://www.uniprot.org/uniprotkb/F1N726" } ], "common_name": "Bovine", "glygen_name": "Bovine", "reference_species": "Bos taurus [9913]" } ], "gene": [ { "name": "GP2", "url": "https://www.uniprot.org/uniprotkb/F1N726", "locus": { "chromosome": "25", "start_pos": 17988345, "end_pos": 18004772, "strand": "+", "evidence": [ { "database": "Ensembl Gene", "id": "ENSBTAG00000006263", "url": "https://www.ensembl.org/id/ENSBTAG00000006263" } ] } } ], "crossref": [ { "id": "F1N726", "url": "https://alphafold.ebi.ac.uk/entry/F1N726", "database": "AlphaFoldDB", "categories": [] }, { "id": "ENSBTAG00000006263", "url": "https://bgee.org/?page=gene&gene_id=ENSBTAG00000006263", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "531420", "url": "https://www.ncbi.nlm.nih.gov/gene/531420", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR001507", "url": "https://www.ebi.ac.uk/interpro/entry/IPR001507", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR017977", "url": "https://www.ebi.ac.uk/interpro/entry/IPR017977", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR042235", "url": "https://www.ebi.ac.uk/interpro/entry/IPR042235", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR048290", "url": "https://www.ebi.ac.uk/interpro/entry/IPR048290", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR055355", "url": "https://www.ebi.ac.uk/interpro/entry/IPR055355", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR055356", "url": "https://www.ebi.ac.uk/interpro/entry/IPR055356", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR057774", "url": "https://www.ebi.ac.uk/interpro/entry/IPR057774", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "bta:531420", "url": "https://www.genome.jp/dbget-bin/www_bget?bta:531420", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "AHICFDP", "url": "https://omabrowser.org/oma/group/AHICFDP/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "A0A3Q1M193", "url": "https://www.orthodb.org/?gene=A0A3Q1M193", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "F1N726", "url": "https://www.orthodb.org/?gene=F1N726", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR14002", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR14002", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR14002:SF16", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR14002:SF16", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00100", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00100", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF23283", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF23283", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF23344", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF23344", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "R-BTA-163125", "url": "https://www.reactome.org/PathwayBrowser/#R-BTA-163125", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "NP_001069418", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001069418", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A3Q1M193", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1M193", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A3Q1M193-1", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1M193-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0AAA9RTF7", "url": "https://www.uniprot.org/uniprotkb/A0AAA9RTF7", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0AAA9RTF7-1", "url": "https://www.uniprot.org/uniprotkb/A0AAA9RTF7-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0AAA9T3D9", "url": "https://www.uniprot.org/uniprotkb/A0AAA9T3D9", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0AAA9T3D9-1", "url": "https://www.uniprot.org/uniprotkb/A0AAA9T3D9-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "F1N726", "url": "https://www.uniprot.org/uniprotkb/F1N726", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "F1N726-1", "url": "https://www.uniprot.org/uniprotkb/F1N726-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MSQLLERMTSVLWLALASYILTLSSTEQQGYRNSTNTGSYEKDLDCGAPGTPEAQLCFDPCQNYTLLNEPFRSTENTEDIQGCDSDKHGWYRFVGDGGVRMPEDCVPTFRCQTSAPLWLNGTHPGLGEGIVNRTACAHWSGNCCLWKTEVLVKACPGPYYVYRLEGTPQCSLRYCTDPATAEDKCDRTCRPEEECRLVSGTWGCFCRQDLNVSDVHSLQPQLDCGDTEIKVSLDKCLLGSLGFGDEVHAYLRDGNWNCSSLRQSEEENWISVTNPTQAGACGNILERNQTHAIYINTLSLVNDFIIRDTILSINFQCAYPLDMKVSLQMALQPIVSSLNITVDGEGEFTVRMALFQDQDYTSPYEGTAVMLSVESMLYVGTILERGDTSRFNLVLKNCYATPTEDKTDPVKYFIIRNSCPNQRDSTISVEENGVSAESRFSVQMFKFAGNYDLVFLHCEVSLCDFIKEECQPSCSRSQLRSEGVAIDPARVLDLGPITRKGAQSLGVMSGTPNTAGFLVAWPLVLLPVLLAGLF", "length": 534, "header": "tr|F1N726-1|F1N726_BOVIN Isoform 1 of Glycoprotein 2 OS=Bos taurus OX=9913 GN=GP2 PE=1 SV=1 CANONICAL=F1N726-1" }, "isoforms": [ { "isoform_ac": "A0A3Q1M193-1", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1M193/entry", "sequence": { "sequence": "MSQLLERMTSVLWLALASYILTLSSTEQQGYRNSTNTGSYEKDLDCGAPGTPEAQLCFDPCQNYTLLNEPFRSTENTEDIQGCDSDKHGWYRFVGDGGVRMPEDCVPTFRCQTSAPLWLNGTHPGLGEGIVNRTACAHWSGNCCLWKTEVLVKACPGPYYVYRLEGTPQCSLRYCTDPATAEDKCDRTCRPEEECRLVSGTWGCFCRQDLNVSDVHSLQPQLDCGDTEIKVSLDKCLLGSLGFGDEVHAYLRDGNWNCSSLRQSEEENWISVTNPTQAGACGNILERNQTHAIYINTLSLVNDFIIRDTILSINFQCAYPLDMKVSLQMALQPIVSSLNITVDGEGEFTVRMALFQDQDYTSPYEGTAVMLSVESMLYVGTILERGDTSRFNLVLKNCYATPTEDKTDPVKYFIIRNSCPNQRDSTISVEENGVSAESRFSVQMFKFAGNYDLVFLHCEVSLCDFIKEECQPSCSRSQLRSEGVAIDPARVLDLGPITRKVLSCVSGFLVAWPLVLLPVLLAGLF", "length": 525, "header": "tr|A0A3Q1M193-1|F1N726_BOVIN Computationally mapped isoform of Glycoprotein 2 OS=Bos taurus OX=9913 GN=GP2 PE=1 SV=1 CANONICAL=F1N726-1" }, "locus": { "chromosome": "25", "start_pos": 18003501, "end_pos": 17988770, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000066639.2", "url": "https://www.ensembl.org/id/ENSBTAT00000066639.2" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000063746.1", "url": "https://www.ensembl.org/id/ENSBTAP00000063746.1" } ] } }, { "isoform_ac": "A0AAA9RTF7-1", "url": "https://www.uniprot.org/uniprotkb/A0AAA9RTF7/entry", "sequence": { "sequence": "MSQLLERMTSVLWLALASYILTLSSTEQQGYRNSTNTGSYEKDLDCGAPGTPEAQLCFDPCQNYTLLNEPFRSTENTEDIQGCDSDKHGWYRFVGDGGVRMPEDCVPTFRCQTSAPLWLNGTHPGLGEGIVNRTACAHWSGNCCLWKTEVLVKACPGPYYVYRLEGTPQCSLRYCTDVHSLQPQLDCGDTEIKVSLDKCLLGSLGFGDEVHAYLRDGNWNCSSLRQSEEENWISVTNPTQAGACGNILERNQTHAIYINTLSLVNDFIIRDTILSINFQCAYPLDMKVSLQMALQPIVSSLNITVDGEGEFTVRMALFQDQDYTSPYEGTAVMLSVESMLYVGTILERGDTSRFNLVLKNCYATPTEDKTDPVKYFIIRNSCPNQRDSTISVEENGVSAESRFSVQMFKFAGNYDLVFLHCEVSLCDFIKEECQPSCSRSQLRSEGVAIDPARVLDLGPITRKGAQSLGVMSGTPNTAGFLVAWPLVLLPVLLAGLF", "length": 497, "header": "tr|A0AAA9RTF7-1|F1N726_BOVIN Computationally mapped isoform of Glycoprotein 2 OS=Bos taurus OX=9913 GN=GP2 PE=1 SV=1 CANONICAL=F1N726-1" }, "locus": { "chromosome": "25", "start_pos": 18003501, "end_pos": 17988770, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000105338.1", "url": "https://www.ensembl.org/id/ENSBTAT00000105338.1" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000076239.1", "url": "https://www.ensembl.org/id/ENSBTAP00000076239.1" } ] } }, { "isoform_ac": "A0AAA9T3D9-1", "url": "https://www.uniprot.org/uniprotkb/A0AAA9T3D9/entry", "sequence": { "sequence": "MSQLLERMTSVLWLALASYILTLSSTEQQDPATAEDKCDRTCRPEEECRLVSGTWGCFCRQDLNVSDVHSLQPQLDCGDTEIKVSLDKCLLGSLGFGDEVHAYLRDGNWNCSSLRQSEEENWISVTNPTQAGACGNILERNQTHAIYINTLSLVNDFIIRDTILSINFQCAYPLDMKVSLQMALQPIVSSLNITVDGEGEFTVRMALFQDQDYTSPYEGTAVMLSVESMLYVGTILERGDTSRFNLVLKNCYATPTEDKTDPVKYFIIRNSCPNQRDSTISVEENGVSAESRFSVQMFKFAGNYDLVFLHCEVSLCDFIKEECQPSCSRSQLRSEGVAIDPARVLDLGPITRKGAQSLGVMSGTPNTAGFLVAWPLVLLPVLLAGLF", "length": 387, "header": "tr|A0AAA9T3D9-1|F1N726_BOVIN Computationally mapped isoform of Glycoprotein 2 OS=Bos taurus OX=9913 GN=GP2 PE=1 SV=1 CANONICAL=F1N726-1" }, "locus": { "chromosome": "25", "start_pos": 18003501, "end_pos": 17988770, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000092433.1", "url": "https://www.ensembl.org/id/ENSBTAT00000092433.1" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000092286.1", "url": "https://www.ensembl.org/id/ENSBTAP00000092286.1" } ] } }, { "isoform_ac": "F1N726-1", "url": "https://www.uniprot.org/uniprotkb/F1N726/entry", "sequence": { "sequence": "MSQLLERMTSVLWLALASYILTLSSTEQQGYRNSTNTGSYEKDLDCGAPGTPEAQLCFDPCQNYTLLNEPFRSTENTEDIQGCDSDKHGWYRFVGDGGVRMPEDCVPTFRCQTSAPLWLNGTHPGLGEGIVNRTACAHWSGNCCLWKTEVLVKACPGPYYVYRLEGTPQCSLRYCTDPATAEDKCDRTCRPEEECRLVSGTWGCFCRQDLNVSDVHSLQPQLDCGDTEIKVSLDKCLLGSLGFGDEVHAYLRDGNWNCSSLRQSEEENWISVTNPTQAGACGNILERNQTHAIYINTLSLVNDFIIRDTILSINFQCAYPLDMKVSLQMALQPIVSSLNITVDGEGEFTVRMALFQDQDYTSPYEGTAVMLSVESMLYVGTILERGDTSRFNLVLKNCYATPTEDKTDPVKYFIIRNSCPNQRDSTISVEENGVSAESRFSVQMFKFAGNYDLVFLHCEVSLCDFIKEECQPSCSRSQLRSEGVAIDPARVLDLGPITRKGAQSLGVMSGTPNTAGFLVAWPLVLLPVLLAGLF", "length": 534, "header": "tr|F1N726-1|F1N726_BOVIN Isoform 1 of Glycoprotein 2 OS=Bos taurus OX=9913 GN=GP2 PE=1 SV=1 CANONICAL=F1N726-1" }, "locus": { "chromosome": "25", "start_pos": 18003501, "end_pos": 17988770, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000008217.6", "url": "https://www.ensembl.org/id/ENSBTAT00000008217.6" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000008217.4", "url": "https://www.ensembl.org/id/ENSBTAP00000008217.4" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [ { "id": "bta:531420", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?bta:531420", "resource": "KEGG Pathway" }, { "id": "R-BTA-163125", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-BTA-163125", "resource": "Reactome", "description": "Post-translational modification: synthesis of GPI-anchored proteins" } ], "orthologs": [ { "uniprot_canonical_ac": "F1RPA7-1", "protein_name": "Glycoprotein 2", "gene_name": "GP2", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MGSMAPVLGLALASCILTLASAEQQGPQNPTKANSYEQVLECGAPGTPEAEHCFDPCKNYTLLDDPSRSTENAELAENCDKDLHGWYRFVGTGGEKMPVDCVPVYRCQTAAPLWLNGTHPTVGEGIVNRTACAHWSGNCCFWKTEVLTKACQGGYHVYRLESTPQCNLRYCTDPTTAIVENKCEKTCRPEEECRLDNGTWSCFCRKDLNSSDVNSLQPQLDCGAKEMKVSVDKCLLGGLGFGDSVSAYLQDRNWNCSSATQRQDGNWISVVSPAQAGACGNVLERNQTHAIYKNTLSLVNNFIIRDTILSIGFQCAYPLDMKVSLQTALQPIVSSLNISVDGAGDFIVRMALFQDPNYTYPYEGAAAVLSVESMLYVGAILEIGDTSHFNLVLRNCYATPSGDRADPVRYFIIRNSCPNQRDSTIRVEENGVSSESRFSVQMFMFAGNYDLVFLHCEVSLCEFLKEQCQPSCSNSQVRGEGGAIDPARVLDLGPITRRGAQSLGVMSGTPSAAGFLVAWPMLLLPLLLAALF", "length": 532 }, "evidence": [ { "id": "F1N726", "url": "https://omabrowser.org/oma/group/F1N726/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "P19218-1", "protein_name": "Pancreatic secretory granule membrane major glycoprotein GP2", "gene_name": "Gp2", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MVACDLLWLAAASCLLTLVFPSTTHQGYGNPRNTSNVDLDCGAPGSSSAGICFDPCQNHTVLNDPSRSTENTVSSEECDSHLRGWYRFVGDGGVKMPETCVNVYRCHTYAPMWLSGSHPILGDGIVNRTACANWNENCCFWSSEVQVKACLGESGEYHVYKLQGTPECSLRYCTDPSTAPKKCEIACRPEEECVFQNNSWTCVCRQDLNVSDTLSLQPLLDCGANEIKVKLDKCLLGGLGFKEDIITYLNDRNCRGTMKDEPNNWVSTTSPVVANDCGNILENNGTQAIYRNTLSLATDFIIRDFLVNVNFQCAYPLDMNVSLQTALQPIVSSLNVDVGGAGEFTVTMALFQDQSYTHPYEGSKVLLPVENILYVGALLNRGDTSRFKLLLTNCYATPSGDRNDIVKYFIIRNRCPNQRDSTINVEENGVSSESRFSVQMFMFAGNYDLVFLHCEVYLCDSTTEQCQPSCSTSRLRSSEPAIDLTRVLDIGPITKKSVQNPDTSNGTPRNTGFLLAWPTFFLPVFLAWLF", "length": 530 }, "evidence": [ { "id": "F1N726", "url": "https://omabrowser.org/oma/group/F1N726/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "P55259-1", "protein_name": "Pancreatic secretory granule membrane major glycoprotein GP2", "gene_name": "GP2", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MPHLMERMVGSGLLWLALVSCILTQASAVQRGYGNPIEASSYGLDLDCGAPGTPEAHVCFDPCQNYTLLDEPFRSTENSAGSQGCDKNMSGWYRFVGEGGVRMSETCVQVHRCQTDAPMWLNGTHPALGDGITNHTACAHWSGNCCFWKTEVLVKACPGGYHVYRLEGTPWCNLRYCTVPRDPSTVEDKCEKACRPEEECLALNSTWGCFCRQDLNSSDVHSLQPQLDCGPREIKVKVDKCLLGGLGLGEEVIAYLRDPNCSSILQTEERNWVSVTSPVQASACRNILERNQTHAIYKNTLSLVNDFIIRDTILNINFQCAYPLDMKVSLQAALQPIVSSLNVSVDGNGEFIVRMALFQDQNYTNPYEGDAVELSVESVLYVGAILEQGDTSRFNLVLRNCYATPTEDKADLVKYFIIRNSCSNQRDSTIHVEENGQSSESRFSVQMFMFAGHYDLVFLHCEIHLCDSLNEQCQPSCSRSQVRSEVPAIDLARVLDLGPITRRGAQSPGVMNGTPSTAGFLVAWPMVLLTVLLAWLF", "length": 537 }, "evidence": [ { "id": "F1N726", "url": "https://omabrowser.org/oma/group/F1N726/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "Q9D733-1", "protein_name": "Pancreatic secretory granule membrane major glycoprotein GP2", "gene_name": "Gp2", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": 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"cell surface", "id": "GO:0009986", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0009986", "evidence": [ { "database": "UniProtKB", "id": "F1N726", "url": "https://www.uniprot.org/uniprotkb/F1N726" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 2, "go_terms": [ { "name": "innate immune response", "id": "GO:0045087", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0045087", "evidence": [ { "database": "UniProtKB", "id": "F1N726", "url": "https://www.uniprot.org/uniprotkb/F1N726" } ], "pmid": "" }, { "name": "neutrophil migration", "id": "GO:1990266", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:1990266", "evidence": [ { "database": "UniProtKB", "id": "F1N726", "url": "https://www.uniprot.org/uniprotkb/F1N726" } ], "pmid": "" } ] }, { "name": "Molecular Function", "total": 1, "go_terms": [ { "name": "antigen binding", "id": "GO:0003823", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003823", "evidence": [ { "database": "UniProtKB", "id": "F1N726", "url": 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] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": 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"IPR016024", "url": "https://www.ebi.ac.uk/interpro/entry/IPR016024", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR021133", "url": "https://www.ebi.ac.uk/interpro/entry/IPR021133", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR051023", "url": "https://www.ebi.ac.uk/interpro/entry/IPR051023", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR054573", "url": "https://www.ebi.ac.uk/interpro/entry/IPR054573", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR055231", "url": "https://www.ebi.ac.uk/interpro/entry/IPR055231", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "A0A3Q1M1U2", "url": "https://www.orthodb.org/?gene=A0A3Q1M1U2", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR10648", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR10648", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR10648:SF2", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR10648:SF2", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF02985", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF02985", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF13646", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF13646", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF22646", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF22646", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF22956", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF22956", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "A0A3Q1M1U2", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1M1U2", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A3Q1M1U2-1", "url": 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phosphatase 2 scaffold subunit Aalpha OS=Bos taurus OX=9913 GN=PPP2R1A PE=3 SV=1 CANONICAL=F6QI68-1" }, "locus": { "chromosome": "18", "start_pos": 58110324, "end_pos": 58087853, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000081552.3", "url": "https://www.ensembl.org/id/ENSBTAT00000081552.3" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000063932.1", "url": "https://www.ensembl.org/id/ENSBTAP00000063932.1" } ] } }, { "isoform_ac": "F6QI68-1", "url": "https://www.uniprot.org/uniprotkb/F6QI68/entry", "sequence": { "sequence": 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"https://www.ensembl.org/id/ENSBTAT00000026449.7" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000026449.5", "url": "https://www.ensembl.org/id/ENSBTAP00000026449.5" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [], "orthologs": [], "go_annotation": {}, "pro_annotation": [], "site_annotation": [ { "start_pos": 327, "end_pos": 329, "annotation": "n_glycosylation_sequon" }, { "start_pos": 568, "end_pos": 570, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "F6QI68", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F6QI68" }, { "id": "PF22956", "database": "Pfam", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF22956" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "PIK3R4-like middle", "eco_id": "ECO_0000259", "start_pos": 168, "end_pos": 286, "start_aa": "Val", "end_aa": "Gln", "glycosite_overlap": [] }, { "evidence": [ { "id": "F6QI68", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F6QI68" }, { "id": "PF22646", "database": "Pfam", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF22646" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "Phosphatase PP2A regulatory subunit A/Splicing factor 3B subunit 1-like HEAT repeat", "eco_id": "ECO_0000259", "start_pos": 291, "end_pos": 372, "start_aa": "Pro", "end_aa": "Gly", "glycosite_overlap": [] } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 327, "end_pos": 329 }, { "start_pos": 568, "end_pos": 570 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ], "tool_support": { "graph_view": "yes" } }, { "uniprot_canonical_ac": "F6R199-1", "uniprot_ac": "F6R199", "uniprot_id": "F6R199_BOVIN", "mass": { "chemical_mass": 53985.0, "monoisotopic_mass": 53985.0 }, "refseq": { "ac": "XP_015327172", "name": "ras GTPase-activating protein-binding protein 2 isoform X1", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_015327172" }, "gene_names": [ { "name": "G3BP2", "type": "recommended", "evidence": [ { "id": "F6R199", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F6R199" } ] }, { "name": "G3BP2", "type": "synonym", "evidence": [ { "id": "XP_015327172", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_015327172" } ] } ], "protein_names": [ { "name": "Ras GTPase-activating protein-binding protein 2", "type": "recommended", "evidence": [ { "id": "F6R199", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F6R199/entry#names_and_taxonomy" } ] }, { "name": "GAP SH3 domain-binding protein 2", "type": "synonym", "evidence": [ { "id": "F6R199", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F6R199/entry#names_and_taxonomy" } ] }, { "name": "ras GTPase-activating protein-binding protein 2 isoform X1", "type": "synonym", "evidence": [ { "id": "XP_015327172", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_015327172" } ] } ], "function": [ { "annotation": "Scaffold protein that plays an essential role in cytoplasmic stress granule formation which acts as a platform for antiviral signaling. Plays an essential role in stress granule formation. Stress granules are membraneless compartments that store mRNAs and proteins, such as stalled translation pre-initiation complexes, in response to stress. Promotes formation of stress granules phase-separated membraneless compartment by undergoing liquid-liquid phase separation (LLPS) upon unfolded RNA-binding: functions as a molecular switch that triggers RNA-dependent LLPS in response to a rise in intracellular free RNA concentrations.", "evidence": [ { "database": "UniProtKB", "id": "A0A3Q1M2X4", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1M2X4#function" }, { "database": "UniProtKB", "id": "ARBA00055663", "url": "https://www.uniprot.org/uniprotkb/ARBA00055663#function" }, { "database": "UniProtKB", "id": "F6R199", "url": "https://www.uniprot.org/uniprotkb/F6R199#function" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Bos taurus", "taxid": 9913, "evidence": [ { "database": "UniProtKB", "id": "F6R199", "url": "https://www.uniprot.org/uniprotkb/F6R199" } ], "common_name": "Bovine", "glygen_name": "Bovine", "reference_species": "Bos taurus [9913]" } ], "gene": [ { "name": "G3BP2", "url": "https://www.uniprot.org/uniprotkb/F6R199", "locus": { "chromosome": "6", "start_pos": 90469442, "end_pos": 90506819, "strand": "+", "evidence": [ { "database": "Ensembl Gene", "id": "ENSBTAG00000014041", "url": "https://www.ensembl.org/id/ENSBTAG00000014041" } ] } } ], "crossref": [ { "id": "F6R199", "url": "https://alphafold.ebi.ac.uk/entry/F6R199", "database": "AlphaFoldDB", "categories": [] }, { "id": "ENSBTAG00000014041", "url": "https://bgee.org/?page=gene&gene_id=ENSBTAG00000014041", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "cd00780", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd00780", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "cd12464", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd12464", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "539249", "url": "https://www.ncbi.nlm.nih.gov/gene/539249", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR000504", "url": "https://www.ebi.ac.uk/interpro/entry/IPR000504", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR002075", "url": "https://www.ebi.ac.uk/interpro/entry/IPR002075", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR012677", "url": "https://www.ebi.ac.uk/interpro/entry/IPR012677", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR018222", "url": "https://www.ebi.ac.uk/interpro/entry/IPR018222", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR032710", "url": "https://www.ebi.ac.uk/interpro/entry/IPR032710", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR034376", "url": "https://www.ebi.ac.uk/interpro/entry/IPR034376", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR035979", "url": "https://www.ebi.ac.uk/interpro/entry/IPR035979", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR039539", "url": "https://www.ebi.ac.uk/interpro/entry/IPR039539", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "RPRGNAY", "url": "https://omabrowser.org/oma/group/RPRGNAY/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "A0A3Q1MHI5", "url": "https://www.orthodb.org/?gene=A0A3Q1MHI5", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR10693", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR10693", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR10693:SF10", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR10693:SF10", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00076", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00076", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF02136", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF02136", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "XP_015327172", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_015327172", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A3Q1M2X4", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1M2X4", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A3Q1M2X4-1", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1M2X4-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A3Q1MHI5", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1MHI5", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A3Q1MHI5-1", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1MHI5-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0AAA9SX82", "url": "https://www.uniprot.org/uniprotkb/A0AAA9SX82", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0AAA9SX82-1", "url": "https://www.uniprot.org/uniprotkb/A0AAA9SX82-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "F6R199", "url": "https://www.uniprot.org/uniprotkb/F6R199", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "F6R199-1", "url": "https://www.uniprot.org/uniprotkb/F6R199-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MVMEKPSPLLVGREFVRQYYTLLNKAPEYLHRFYGRNSSYVHGGVDASGKPQEAVYGQNDIHHKVLSLNFSECHTKIRHVDAHATLSDGVVVQVMGLLSNSGQPERKFMQTFVLAPEGSVPNKFYVHNDMFRYEDEVFGDSEPELDEESEDEVEEEQEERQPSPEPVQENANSGYYEAHPVTNGIEEPLEESSHEPEPEPESETKTEELKPPVEEKNLEELEEKSASPPPAEPVSLPQEPPKAFSWASVTSKNLPPSGTVSSSGIPPHVKAPVSQPRVEAKPEVQSQPPRVREQRPRERPGFPPRGPRPGRGDIEQNESDNRRIIRYPDSHQLFVGNLPHDIDENELKEFFMSFGNVVELRINTKGVGGKLPNFGFVVFDDSEPVQRILIAKPIMFRGEVRLNVEEKKTRAARERETRGGGDDRRDIRRSDRGPGGPRGIVGGGMMRDRDGRGPPPRGGMAQKLGSGRGAGQMEGRFTGQRR", "length": 482, "header": "tr|F6R199-1|F6R199_BOVIN Isoform 1 of Ras GTPase-activating protein-binding protein 2 OS=Bos taurus OX=9913 GN=G3BP2 PE=1 SV=1 CANONICAL=F6R199-1" }, "isoforms": [ { "isoform_ac": "A0A3Q1M2X4-1", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1M2X4/entry", "sequence": { "sequence": "MSTNRKYLTLCSKEMVMEKPSPLLVGREFVRQYYTLLNKAPEYLHRFYGRNSSYVHGGVDASGKPQEAVYGQNDIHHKVLSLNFSECHTKIRHVDAHATLSDGVVVQVMGLLSNSGQPERKFMQTFVLAPEGSVPNKFYVHNDMFRYEDEVFGDSEPELDEESEDEVEEEQEERQPSPEPVQENANSGYYEAHPVTNGIEEPLEESSHEPEPEPESETKTEELKPPVEEKNLEELEEKSASPPPAEPVSLPQEPPKPRVEAKPEVQSQPPRVREQRPRERPGFPPRGPRPGRGDIEQNESDNRRIIRYPDSHQLFVGNLPHDIDENELKEFFMSFGNVVELRINTKGVGGKLPNFGFVVFDDSEPVQRILIAKPIMFRGEVRLNVEEKKTRAARERETRGGGDDRRDIRRSDRGPGGPRGIVGGGMMRDRDGRGPPPRGGMAQKLGSGRGAGQMEGRFTGQRR", "length": 463, "header": "tr|A0A3Q1M2X4-1|F6R199_BOVIN Computationally mapped isoform of Ras GTPase-activating protein-binding protein 2 OS=Bos taurus OX=9913 GN=G3BP2 PE=1 SV=1 CANONICAL=F6R199-1" }, "locus": { "chromosome": "6", "start_pos": 90506620, "end_pos": 90470500, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000071110.2", "url": "https://www.ensembl.org/id/ENSBTAT00000071110.2" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000067798.2", "url": "https://www.ensembl.org/id/ENSBTAP00000067798.2" } ] } }, { "isoform_ac": "A0A3Q1MHI5-1", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1MHI5/entry", "sequence": { "sequence": "MVMEKPSPLLVGREFVRQYYTLLNKAPEYLHRFYGRNSSYVHGGVDASGKPQEAVYGQNDIHHKVLSLNFSECHTKIRHVDAHATLSDGVVVQVMGLLSNSGQPERKFMQTFVLAPEGSVPNKFYVHNDMFRYEDEVFGDSEPELDEESEDEVEEEQEERQPSPEPVQENANSGYYEAHPVTNGIEEPLEESSHEPEPEPESETKTEELKPPVEEKNLEELEEKSASPPPAEPVSLPQEPPKAFSWASVTSKNLPPSGTVSSSGIPPHVKAPVSQPRVEAKPEVQSQPPRVREQRPRERPGFPPRGPRPGRGDIEQNESDNRRIIRYPDSHQLFVGNLPHDIDENELKEFFMTNYVSRGSTFKCGREKDKSCQRARNSRWW", "length": 381, "header": "tr|A0A3Q1MHI5-1|F6R199_BOVIN Computationally mapped isoform of Ras GTPase-activating protein-binding protein 2 OS=Bos taurus OX=9913 GN=G3BP2 PE=1 SV=2 CANONICAL=F6R199-1" }, "locus": { "chromosome": "6", "start_pos": 90485079, "end_pos": 90470684, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000075647.2", "url": "https://www.ensembl.org/id/ENSBTAT00000075647.2" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000070122.2", "url": "https://www.ensembl.org/id/ENSBTAP00000070122.2" } ] } }, { "isoform_ac": "A0AAA9SX82-1", "url": "https://www.uniprot.org/uniprotkb/A0AAA9SX82/entry", "sequence": { "sequence": "MVMEKPSPLLVGREFVRQYYTLLNKAPEYLHRFYGRNSSYVHGGVDASGKPQEAVYGQNGSVPNKFYVHNDMFRYEDEVFGDSEPELDEESEDEVEEEQEERQPSPEPVQENANSGYYEAHPVTNGIEEPLEESSHEPEPEPESETKTEELKPPVEEKNLEELEEKSASPPPAEPVSLPQEPPKAFSWASVTSKNLPPSGTVSSSGIPPHVKAPVSQPRVEAKPEVQSQPPRVREQRPRERPGFPPRGPRPGRGDIEQNESDNRRIIRYPDSHQLFVGNLPHDIDENELKEFFMSFGNVVELRINTKGVGGKLPNFGFVVFDDSEPVQRILIAKPIMFRGEVRLNVEEKKTRAARERETRGGGDDRRDIRRSDRGPGGPRGIVGGGMMRDRDGRGPPPRGGMAQKLGSGRGAGQMEGRFTGQRR", "length": 424, "header": "tr|A0AAA9SX82-1|F6R199_BOVIN Computationally mapped isoform of Ras GTPase-activating protein-binding protein 2 OS=Bos taurus OX=9913 GN=G3BP2 PE=1 SV=1 CANONICAL=F6R199-1" }, "locus": { "chromosome": "6", "start_pos": 90485079, "end_pos": 90470500, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000128531.1", "url": "https://www.ensembl.org/id/ENSBTAT00000128531.1" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000089949.1", "url": "https://www.ensembl.org/id/ENSBTAP00000089949.1" } ] } }, { "isoform_ac": "F6R199-1", "url": "https://www.uniprot.org/uniprotkb/F6R199/entry", "sequence": { "sequence": "MVMEKPSPLLVGREFVRQYYTLLNKAPEYLHRFYGRNSSYVHGGVDASGKPQEAVYGQNDIHHKVLSLNFSECHTKIRHVDAHATLSDGVVVQVMGLLSNSGQPERKFMQTFVLAPEGSVPNKFYVHNDMFRYEDEVFGDSEPELDEESEDEVEEEQEERQPSPEPVQENANSGYYEAHPVTNGIEEPLEESSHEPEPEPESETKTEELKPPVEEKNLEELEEKSASPPPAEPVSLPQEPPKAFSWASVTSKNLPPSGTVSSSGIPPHVKAPVSQPRVEAKPEVQSQPPRVREQRPRERPGFPPRGPRPGRGDIEQNESDNRRIIRYPDSHQLFVGNLPHDIDENELKEFFMSFGNVVELRINTKGVGGKLPNFGFVVFDDSEPVQRILIAKPIMFRGEVRLNVEEKKTRAARERETRGGGDDRRDIRRSDRGPGGPRGIVGGGMMRDRDGRGPPPRGGMAQKLGSGRGAGQMEGRFTGQRR", "length": 482, "header": "tr|F6R199-1|F6R199_BOVIN Isoform 1 of Ras GTPase-activating protein-binding protein 2 OS=Bos taurus OX=9913 GN=G3BP2 PE=1 SV=1 CANONICAL=F6R199-1" }, "locus": { "chromosome": "6", "start_pos": 90485079, "end_pos": 90470500, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000018663.4", "url": "https://www.ensembl.org/id/ENSBTAT00000018663.4" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000018663.3", "url": "https://www.ensembl.org/id/ENSBTAP00000018663.3" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [], "orthologs": [ { "uniprot_canonical_ac": "E1C769-1", "protein_name": "Ras GTPase-activating protein-binding protein 2", "gene_name": "G3BP2", "tax_id": 9031, "organism": "Gallus gallus", "sequence": { "sequence": "MVMEKPSPLLVGREFVRQYYTLLNKAPDFLHRFYGRNSSYVHGGLDASGKPQEAVYGQAEIHKKVMSLQFSECHTKIRHVDAHATLSDGVVVQVMGELSNNGQPMRKFMQTFVLAPEGSVPNKFYVHNDIFRYEDEVFGDSEGELDEESEEEVEEEQEERQPSPEPVQENASSTYYENHPVTNGIEEALEESSHEPEPELESETKPEELKTEVEEKALEELEEKSPSPPPVEPVSLPQEPPKAFSWASVTSKNLPPSGTVSSSGIPPHVKAPVSQPRVETKPEAQSQPPRVREQRPRERPGFPPRGPRPGRGDVEQNESDNRRIIRYPDSHQLFVGNLPHDIDESELKEFFMSFGNVVELRINTKGVGGKLPNFGFVVFDDSEPVQRILVAKPIMFRGEVRLNVEEKKTRAARERETRGGGDDRRDIRRNDRGPGGPRGIVGGGMMRDRDGRGPPPRGGMAQKLGSGRGSGQMEGRFTGQRR", "length": 482 }, "evidence": [ { "id": "F6R199", "url": "https://omabrowser.org/oma/group/F6R199/", "database": "OMA" } ], "glygen_name": "Chicken", "common_name": "Chicken" }, { "uniprot_canonical_ac": "G3I9F1-1", "protein_name": "Ras GTPase-activating protein-binding protein 2", "gene_name": "G3bp2", "tax_id": 10029, "organism": "Cricetulus griseus", "sequence": { "sequence": "MVMEKPSPLLVGREFVRQYYTLLNKAPEYLHRFYGRNSSYVHGGVDASGKPQEAVYGQNDIHHKVLSLNFSECHTKIRHVDAHATLSDGVVVQVMGLLSNSGQPERKFMQTFVLAPEGSVPNKFYVHNDMFRYEDEVFGDSEPELDEESEDEVEEEQEERQPSPEPVQENANSAYYDALPVTNGIEEPLEEPSHEPEPEPESETKAEELKPQVEEKNLEELEEKSTTPPPSEPASLPQEPPKAFSWASVTSKNLPPSGTVSSSGIPPHVKAPVSQPRVEAKPEVQSQPPRVREQRPRERPGFTPRGPRPGRGDMEQNDSDNRRIIRYPDSHQLFVGNLPHDIDENELKEFFMSFGNVVELRINTKGVGGKLPNFGFVVFDDSEPVQRILIAKPIMFRGEVRLNVEEKKTRAARERETRGGGDDRRDIRRSDRGPGGPRGIVGGGMMRDRDGRGPPPRGGMTQKLGSGRGTGQMEGRFTGQRR", "length": 482 }, "evidence": [ { "id": "F6R199", "url": "https://omabrowser.org/oma/group/F6R199/", "database": "OMA" } ], "glygen_name": "Hamster", "common_name": "Chinese hamster" }, { "uniprot_canonical_ac": "I3LPH5-1", "protein_name": "Ras GTPase-activating protein-binding protein 2", "gene_name": "G3BP2", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MVMEKPSPLLVGREFVRQYYTLLNKAPEYLHRFYGRNSSYVHGGVDASGKPQEAVYGQNDIHHKVLSLNFSECHTKIRHVDAHATLSDGVVVQVMGLLSNSGQPERKFMQTFVLAPEGSVPNKFYVHNDMFRYEDEVFGDSEPELDEESEDEVEEEQEERQPTPEPVQETNSGYYEAHPVTNGIEEPLEESSHEPEPEPESETKTEELKPQVEEKNLEELEEKSTSPPPAEPVSLPQEPPKAFSWASVTSKNLPPSGTVSSSGIPPHVKAPVSQPRVETKPEVQSQPPRVREQRPRERPGFPPRGPRPGRGDIEQNESDNRRIIRYPDSHQLFVGNLPHDIDENELKEFFMSFGNVVELRINTKGVGGKLPNFGFVVFDDSEPVQRILIAKPIMFRGEVRLNVEEKKTRAARERETRGGGDDRRDIRRNDRGPGGPRGVVGGGMMRDRDGRGPPPRGGMAQKLGSGRGTGQMEGRFTGQRR", "length": 481 }, "evidence": [ { "id": "F6R199", "url": "https://omabrowser.org/oma/group/F6R199/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "P97379-1", "protein_name": "Ras GTPase-activating protein-binding protein 2", "gene_name": "G3bp2", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MVMEKPSPLLVGREFVRQYYTLLNKAPEYLHRFYGRNSSYVHGGVDASGKPQEAVYGQNDIHHKVLSLNFSECHTKIRHVDAHATLSDGVVVQVMGLLSNSGQPERKFMQTFVLAPEGSVPNKFYVHNDMFRYEDEVFGDSEPELDEESEDEVEEEQEDRQPSPEPVQENANSAYYDAHPVTNGIEEPLEESSHEPEPEPESETKTEELKPQVEEKHLEELEEKSATPPPAEPASLPQEPPKAFSWASVTSKNLPPSGTVSSSGIPPHVKAPVSQPRVDAKPEVQSQPPRVREQRPRERPGFPPRGPRPGRGDMEQNDSDNRRIIRYPDSHQLFVGNLPHDIDENELKEFFMSFGNVVELRINTKGVGGKLPNFGFVVFDDSEPVQRILIAKPIMFRGEVRLNVEEKKTRAARERETRGGGDDRRDIRRNDRGPGGPRGIVGGGMMRDRDGRGPPPRGGMTQKLGSGRGTGQMEGRFTGQRR", "length": 482 }, "evidence": [ { "id": "F6R199", "url": "https://omabrowser.org/oma/group/F6R199/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q54Z21-1", "protein_name": "RNA recognition motif-containing protein RRM", "gene_name": "", "tax_id": 44689, "organism": "Dictyostelium discoideum", "sequence": { "sequence": "MEMINTVAASFLLKYFTLLIKTPENLKDFYHQNSKITRRFENGKANILTSYDNINEFLVNNSAKFGGNANISSIDCQPLGESIFMTCIGSIGFDGNVRRFLQSFYLEKIQGSFFISNDIFAFTSDEVFTVAIEQPDEASNIEQDYQQQQQQTVEVESTTTTTTTTTAIVAASPTVDAEIVKQPEEPVKVEQPPTPKASNVEQIIETTSTTTTTTTAAAAAVTTINASTSTPTPTETKAVETTKKPEPTTNTTTNTTTPAEKPKETTPAPHQKQTWAQLVLINSTAQTASASEEPTQSSSSSSSQPSSSPSSSSSSVNNNSNTTTTTNNTTTTTTANKQKDDHHFSKDGNTVFISFKSSKVDQAPIKEAFNQFGVVSNVRILTGYGFVEFEKPESVQNALNYASTHSNKINVAGNIIKVEERRGALPTGKQQQQSPPSSSSSPSSSQPLKQQPQQPYKRQPQNNGAINLKYNNQQNKPNLNGNNINNNNNNNNNNNSNNQNNFRKPQKVDNKKEASK", "length": 516 }, "evidence": [ { "id": "F6R199", "url": "https://omabrowser.org/oma/group/F6R199/", "database": "OMA" } ], "glygen_name": "Cellular slime mold", "common_name": "Social amoeba" }, { "uniprot_canonical_ac": "Q9UN86-1", "protein_name": "Ras GTPase-activating protein-binding protein 2", "gene_name": "G3BP2", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MVMEKPSPLLVGREFVRQYYTLLNKAPEYLHRFYGRNSSYVHGGVDASGKPQEAVYGQNDIHHKVLSLNFSECHTKIRHVDAHATLSDGVVVQVMGLLSNSGQPERKFMQTFVLAPEGSVPNKFYVHNDMFRYEDEVFGDSEPELDEESEDEVEEEQEERQPSPEPVQENANSGYYEAHPVTNGIEEPLEESSHEPEPEPESETKTEELKPQVEEKNLEELEEKSTTPPPAEPVSLPQEPPKAFSWASVTSKNLPPSGTVSSSGIPPHVKAPVSQPRVEAKPEVQSQPPRVREQRPRERPGFPPRGPRPGRGDMEQNDSDNRRIIRYPDSHQLFVGNLPHDIDENELKEFFMSFGNVVELRINTKGVGGKLPNFGFVVFDDSEPVQRILIAKPIMFRGEVRLNVEEKKTRAARERETRGGGDDRRDIRRNDRGPGGPRGIVGGGMMRDRDGRGPPPRGGMAQKLGSGRGTGQMEGRFTGQRR", "length": 482 }, "evidence": [ { "id": "F6R199", "url": "https://omabrowser.org/oma/group/F6R199/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" } ], "go_annotation": { "categories": [ { "name": "Molecular Function", "total": 3, "go_terms": [ { "name": "RNA binding", "id": "GO:0003723", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003723", "evidence": [ { "database": "UniProtKB", "id": "F6R199", "url": "https://www.uniprot.org/uniprotkb/F6R199" } ], "pmid": "" }, { "name": "mRNA binding", "id": "GO:0003729", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003729", "evidence": [ { "database": "UniProtKB", "id": "F6R199", "url": "https://www.uniprot.org/uniprotkb/F6R199" } ], "pmid": "" }, { "name": "molecular condensate scaffold activity", "id": "GO:0140693", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0140693", "evidence": [ { "database": "UniProtKB", "id": "F6R199", "url": "https://www.uniprot.org/uniprotkb/F6R199" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 4, "go_terms": [ { "name": "innate immune response", "id": "GO:0045087", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0045087", "evidence": [ { "database": "UniProtKB", "id": "F6R199", "url": "https://www.uniprot.org/uniprotkb/F6R199" } ], "pmid": "" }, { "name": "mRNA transport", "id": "GO:0051028", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0051028", "evidence": [ { "database": "UniProtKB", "id": "F6R199", "url": "https://www.uniprot.org/uniprotkb/F6R199" } ], "pmid": "" }, { "name": "stress granule assembly", "id": "GO:0034063", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0034063", "evidence": [ { "database": "UniProtKB", "id": "F6R199", "url": "https://www.uniprot.org/uniprotkb/F6R199" } ], "pmid": "" }, { "name": "protein homooligomerization", "id": "GO:0051260", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0051260", "evidence": [ { "database": "UniProtKB", "id": "F6R199", "url": "https://www.uniprot.org/uniprotkb/F6R199" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 2, "go_terms": [ { "name": "cytoplasmic stress granule", "id": "GO:0010494", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0010494", "evidence": [ { "database": "UniProtKB", "id": "F6R199", "url": "https://www.uniprot.org/uniprotkb/F6R199" } ], "pmid": "" }, { "name": "cytosol", "id": "GO:0005829", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005829", "evidence": [ { "database": "UniProtKB", "id": "F6R199", "url": "https://www.uniprot.org/uniprotkb/F6R199" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 317, "end_pos": 319, "annotation": "n_glycosylation_sequon" }, { "start_pos": 37, "end_pos": 39, "annotation": "n_glycosylation_sequon" }, { "start_pos": 69, "end_pos": 71, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "F6R199", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F6R199" }, { "id": "PS50177", "database": "PROSITE", "url": "https://prosite.expasy.org/PS50177" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "NTF2", "eco_id": "ECO_0000259", "start_pos": 11, "end_pos": 133, "start_aa": "Val", "end_aa": "Tyr", "glycosite_overlap": [] }, { "evidence": [ { "id": "F6R199", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F6R199" }, { "id": "PS50102", "database": "PROSITE", "url": "https://prosite.expasy.org/PS50102" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "RRM", "eco_id": "ECO_0000259", "start_pos": 331, "end_pos": 409, "start_aa": "His", "end_aa": "Thr", "glycosite_overlap": [] } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" }, { "name": "homologset.oma", "label": "OMA Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 317, "end_pos": 319 }, { "start_pos": 37, "end_pos": 39 }, { "start_pos": 69, "end_pos": 71 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { 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"monoisotopic_mass": 77226.0 }, "refseq": {}, "gene_names": [ { "name": "APBB1", "type": "recommended", "evidence": [ { "id": "F6R6E5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F6R6E5" } ] } ], "protein_names": [ { "name": "Amyloid beta protein binding family B member 1", "type": "synonym", "evidence": [ { "id": "F6R6E5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F6R6E5/entry#names_and_taxonomy" } ] } ], "function": [], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Bos taurus", "taxid": 9913, "evidence": [ { "database": "UniProtKB", "id": "F6R6E5", "url": "https://www.uniprot.org/uniprotkb/F6R6E5" } ], "common_name": "Bovine", "glygen_name": "Bovine", "reference_species": "Bos taurus [9913]" } ], "gene": [ { "name": "APBB1", "url": "https://www.uniprot.org/uniprotkb/F6R6E5", "locus": { "chromosome": "15", "start_pos": 46648787, "end_pos": 46625971, "strand": "-", "evidence": [ { "database": "Ensembl Gene", "id": "ENSBTAG00000015655", "url": "https://www.ensembl.org/id/ENSBTAG00000015655" } ] } } ], "crossref": [ { "id": "F6R6E5", "url": "https://alphafold.ebi.ac.uk/entry/F6R6E5", "database": "AlphaFoldDB", "categories": [] }, { "id": "ENSBTAG00000015655", "url": "https://bgee.org/?page=gene&gene_id=ENSBTAG00000015655", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "cd00201", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd00201", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "cd01271", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd01271", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "cd01272", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd01272", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "IPR001202", "url": "https://www.ebi.ac.uk/interpro/entry/IPR001202", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR006020", "url": "https://www.ebi.ac.uk/interpro/entry/IPR006020", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR011993", "url": "https://www.ebi.ac.uk/interpro/entry/IPR011993", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR036020", "url": "https://www.ebi.ac.uk/interpro/entry/IPR036020", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR039576", "url": "https://www.ebi.ac.uk/interpro/entry/IPR039576", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "A0A3Q1MU04", "url": "https://www.orthodb.org/?gene=A0A3Q1MU04", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR14058", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR14058", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR14058:SF5", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR14058:SF5", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00397", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00397", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF00640", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00640", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "R-BTA-5693565", "url": "https://www.reactome.org/PathwayBrowser/#R-BTA-5693565", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "A0A3Q1M4W6", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1M4W6", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A3Q1M4W6-1", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1M4W6-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A3Q1MU04", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1MU04", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A3Q1MU04-1", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1MU04-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0AAA9S0U3", "url": "https://www.uniprot.org/uniprotkb/A0AAA9S0U3", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0AAA9S0U3-1", "url": "https://www.uniprot.org/uniprotkb/A0AAA9S0U3-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "F6R6E5", "url": "https://www.uniprot.org/uniprotkb/F6R6E5", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "F6R6E5-1", "url": "https://www.uniprot.org/uniprotkb/F6R6E5-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MSVPSSLSQSAINANSHGGPALSLPLPLHAAHNQLLNAKLQATAVGPKDLRSAMGEGGGPEPGPANAKWLKEGQNQLRRAATAHRDQNRNVTLTLAEEASQEPEMAPLGPKGLMHLYSELELSAHNAANRGPRGPGLIISTQEQGPDEGEEKAAGEAEEDDEEEEEEEEEDLSSPPGLPEPLESTEVPPGPQALADGPREHSKSASLLFGMRNSAASDEDSSWATLSQGSPSYGSPEDTDSFWNPNAFETDSDLPAGWMRVQDTSGTYYWHIPTGTTQWEPPGRASPSQGSSPREESQLTWTGFTHGERFEDGEFWKDEPSEEAPMDLGLKDPEEGMLPFPAQSLSPEPLPQEEEKLPPRNANPGIKCFAVRSLGWVEMTEEELAPGRSSVAVNNCIRQLSYHKNNLHDPMSGGWGEGKDLLLQLEDETLKLVEPHSQALLHTQPIVSIRVWGVGRDSGRERDFAYVARDKLTQMLKCHVFRCEAPAKNIATSLHEICSKIMAERRNARCLVNGLSLDHSKLVDVPFQVEFPAPKNELVQKFQVYYLGNVPVAKPVGVDVINGALESVLSSSSREQWTPSHVSVAPATLTILHQQTEAVLGECRVRFLSFLAVGRDVHTFAFIMAAGPASFCCHMFWCEPNAASLSEAVQAACMLRYQKCLDARSQASTSCLPAPPAESVARRVGWTVRRGVQSLWGSLKPKRLGSHTP", "length": 709, "header": "tr|F6R6E5-1|F6R6E5_BOVIN Isoform 1 of Amyloid beta protein binding family B member 1 OS=Bos taurus OX=9913 GN=APBB1 PE=4 SV=1 CANONICAL=F6R6E5-1" }, "isoforms": [ { "isoform_ac": "A0A3Q1M4W6-1", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1M4W6/entry", "sequence": { "sequence": "MSQVCDSFWNPNAFETDSDLPAGWMRVQDTSGTYYWHIPTGTTQWEPPGRASPSQGSSPREESQLTWTGFTHGERFEDGEFWKDEPSEEAPMDLGLKDPEEGMLPFPAQSLSPEPLPQEEEKLPPRNANPGIKCFAVRSLGWVEMTEEELAPGRSSVAVNNCIRQLSYHKNNLHDPMSGGWGEGKDLLLQLEDETLKLVEPHSQALLHTQPIVSIRVWGVGRDSGRERDFAYVARDKLTQMLKCHVFRCEAPAKNIATSLHEICSKIMAERRNARCLVNGLSLDHSKLVDVPFQVEFPAPKNELVQKFQVYYLGNVPVAKPVGVDVINGALESVLSSSSREQWTPSHVSVAPATLTILHQQTEAVLGECRVRFLSFLAVGRDVHTFAFIMAAGPASFCCHMFWCEPNAASLSEAVQAACMLRYQKCLDARSQASTSCLPAPPAESVARRVGWTVRRGVQSLWGSLKPKRLGSHTP", "length": 475, "header": "tr|A0A3Q1M4W6-1|F6R6E5_BOVIN Computationally mapped isoform of Amyloid beta protein binding family B member 1 OS=Bos taurus OX=9913 GN=APBB1 PE=4 SV=1 CANONICAL=F6R6E5-1" }, "locus": { "chromosome": "15", "start_pos": 46648371, "end_pos": 46639125, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000072320.3", "url": "https://www.ensembl.org/id/ENSBTAT00000072320.3" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000068664.2", "url": "https://www.ensembl.org/id/ENSBTAP00000068664.2" } ] } }, { "isoform_ac": "A0A3Q1MU04-1", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1MU04/entry", "sequence": { "sequence": "MAAGEGVGGAGLLVAAGCRREDPSARPPGAQDGAPPPPLPRARLRRSGRGPAARALLGGGCCDGEAAAEPEPRSLSHLHHLGLGPPRAGFAEAMSVPSSLSQSAINANSHGGPALSLPLPLHAAHNQLLNAKLQATAVGPKDLRSAMGEGGGPEPGPANAKWLKEGQNQLRRAATAHRDQNRNVTLTLAEEASQEPEMAPLGPKGLMHLYSELELSAHNAANRGPRGPGLIISTQEQGPDEGEEKAAGEAEEDDEEEEEEEEEDLSSPPGLPEPLESTEVPPGPQALADGPREHSKSASLLFGMRNSAASDEDSSWATLSQGSPSYGSPEDTDSFWNPNAFETDSDLPAGWMRVQDTSGTYYWHIPTGTTQWEPPGRASPSQGSSPREESQLTWTGFTHGERFEDGEFWKDEPSEEAPMDLGLKDPEEGMLPFPAQSLSPEPLPQEEEKLPPRNANPGIKCFAVRSLGWVEMTEEELAPGRSSVAVNNCIRQLSYHKNNLHDPMSGGWGEGKDLLLQLEDETLKLVEPHSQALLHTQPIVSIRVWGVGRDSGRDFAYVARDKLTQMLKCHVFRCEAPAKNIATSLHEICSKIMAERRNARCLVNGLSLDHSKLVDVPFQVEFPAPKNELVQKFQVYYLGNVPVAKPVGVDVINGALESVLSSSSREQWTPSHVSVAPATLTILHQQTEAVLGECRVRFLSFLAVGRDVHTFAFIMAAGPASFCCHMFWCEPNAASLSEAVQAACMLRYQKCLDARSQASTSCLPAPPAESVARRVGWTVRRGVQSLWGSLKPKRLGSHTP", "length": 800, "header": "tr|A0A3Q1MU04-1|A0A3Q1MU04_BOVIN Computationally mapped isoform of Amyloid beta protein binding family B member 1 OS=Bos taurus OX=9913 GN=APBB1 PE=4 SV=2 CANONICAL=F6R6E5-1" }, "locus": { "chromosome": "15", "start_pos": 46648371, "end_pos": 46626170, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000069360.2", "url": "https://www.ensembl.org/id/ENSBTAT00000069360.2" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000073951.2", "url": "https://www.ensembl.org/id/ENSBTAP00000073951.2" } ] } }, { "isoform_ac": "A0AAA9S0U3-1", "url": "https://www.uniprot.org/uniprotkb/A0AAA9S0U3/entry", "sequence": { "sequence": "RSAMFSQDFFLAILLQDSSPDSFWNPNAFETDSDLPAGWMRVQDTSGTYYWHIPTGTTQWEPPGRASPSQGSSPREESQLTWTGFTHGERFEDGEFWKDEPSEEAPMDLGLKDPEEGMLPFPAQSLSPEPLPQEEEKLPPRNANPGIKCFAVRSLGWVEMTEEELAPGRSSVAVNNCIRQLSYHKNNLHDPMSGGWGEGKDLLLQLEDETLKLVEPHSQALLHTQPIVSIRVWGVGRDSGRERDFAYVARDKLTQMLKCHVFRCEAPAKNIATSLHEICSKIMAERRNARCLVNGLSLDHSKLVDVPFQVEFPAPKNELVQKFQVYYLGNVPVAKPVGVDVINGALESVLSSSSREQWTPSHVSVAPATLTILHQQTEAVLGECRVRFLSFLAVGRDVHTFAFIMAAGPASFCCHMFWCEPNAASLSEAVQAACMLRYQKCLDARSQASTSCLPAPPAESVARRVGWTVRRGVQSLWGSLKPKRLGSHTP", "length": 490, "header": "tr|A0AAA9S0U3-1|F6R6E5_BOVIN Computationally mapped isoform of Amyloid beta protein binding family B member 1 OS=Bos taurus OX=9913 GN=APBB1 PE=4 SV=1 CANONICAL=F6R6E5-1" }, "locus": { "chromosome": "15", "start_pos": 46648371, "end_pos": 46638942, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000114128.2", "url": "https://www.ensembl.org/id/ENSBTAT00000114128.2" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000078592.1", "url": "https://www.ensembl.org/id/ENSBTAP00000078592.1" } ] } }, { "isoform_ac": "F6R6E5-1", "url": "https://www.uniprot.org/uniprotkb/F6R6E5/entry", "sequence": { "sequence": "MSVPSSLSQSAINANSHGGPALSLPLPLHAAHNQLLNAKLQATAVGPKDLRSAMGEGGGPEPGPANAKWLKEGQNQLRRAATAHRDQNRNVTLTLAEEASQEPEMAPLGPKGLMHLYSELELSAHNAANRGPRGPGLIISTQEQGPDEGEEKAAGEAEEDDEEEEEEEEEDLSSPPGLPEPLESTEVPPGPQALADGPREHSKSASLLFGMRNSAASDEDSSWATLSQGSPSYGSPEDTDSFWNPNAFETDSDLPAGWMRVQDTSGTYYWHIPTGTTQWEPPGRASPSQGSSPREESQLTWTGFTHGERFEDGEFWKDEPSEEAPMDLGLKDPEEGMLPFPAQSLSPEPLPQEEEKLPPRNANPGIKCFAVRSLGWVEMTEEELAPGRSSVAVNNCIRQLSYHKNNLHDPMSGGWGEGKDLLLQLEDETLKLVEPHSQALLHTQPIVSIRVWGVGRDSGRERDFAYVARDKLTQMLKCHVFRCEAPAKNIATSLHEICSKIMAERRNARCLVNGLSLDHSKLVDVPFQVEFPAPKNELVQKFQVYYLGNVPVAKPVGVDVINGALESVLSSSSREQWTPSHVSVAPATLTILHQQTEAVLGECRVRFLSFLAVGRDVHTFAFIMAAGPASFCCHMFWCEPNAASLSEAVQAACMLRYQKCLDARSQASTSCLPAPPAESVARRVGWTVRRGVQSLWGSLKPKRLGSHTP", "length": 709, "header": "tr|F6R6E5-1|F6R6E5_BOVIN Isoform 1 of Amyloid beta protein binding family B member 1 OS=Bos taurus OX=9913 GN=APBB1 PE=4 SV=1 CANONICAL=F6R6E5-1" }, "locus": { "chromosome": "15", "start_pos": 46648371, "end_pos": 46633174, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000020791.8", "url": "https://www.ensembl.org/id/ENSBTAT00000020791.8" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000020791.6", "url": "https://www.ensembl.org/id/ENSBTAP00000020791.6" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [ { "id": "R-BTA-5693565", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-BTA-5693565", "resource": "Reactome", "description": "Recruitment and ATM-mediated phosphorylation of repair and signaling proteins at DNA double strand breaks" } ], "orthologs": [], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 6, "go_terms": [ { "name": "cytoplasm", "id": "GO:0005737", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005737", "evidence": [ { "database": "UniProtKB", "id": "F6R6E5", "url": "https://www.uniprot.org/uniprotkb/F6R6E5" } ], "pmid": "" }, { "name": "nucleus", "id": "GO:0005634", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005634", "evidence": [ { "database": "UniProtKB", "id": "F6R6E5", "url": "https://www.uniprot.org/uniprotkb/F6R6E5" } ], "pmid": "" }, { "name": "plasma membrane", "id": "GO:0005886", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005886", "evidence": [ { "database": "UniProtKB", "id": "F6R6E5", "url": "https://www.uniprot.org/uniprotkb/F6R6E5" } ], "pmid": "" }, { "name": "lamellipodium", "id": "GO:0030027", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030027", "evidence": [ { "database": "UniProtKB", "id": "F6R6E5", "url": "https://www.uniprot.org/uniprotkb/F6R6E5" } ], "pmid": "" }, { "name": "growth cone", "id": "GO:0030426", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030426", "evidence": [ { "database": "UniProtKB", "id": "F6R6E5", "url": "https://www.uniprot.org/uniprotkb/F6R6E5" } ], "pmid": "" }, { "name": "synapse", "id": "GO:0045202", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0045202", "evidence": [ { "database": "UniProtKB", "id": "F6R6E5", "url": "https://www.uniprot.org/uniprotkb/F6R6E5" } ], "pmid": "" } ] }, { "name": "Molecular Function", "total": 6, "go_terms": [ { "name": "amyloid-beta binding", "id": "GO:0001540", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0001540", "evidence": [ { "database": "UniProtKB", "id": "F6R6E5", "url": "https://www.uniprot.org/uniprotkb/F6R6E5" } ], "pmid": "" }, { "name": "molecular adaptor activity", "id": "GO:0060090", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0060090", "evidence": [ { "database": "UniProtKB", "id": "F6R6E5", "url": "https://www.uniprot.org/uniprotkb/F6R6E5" } ], "pmid": "" }, { "name": "chromatin binding", "id": "GO:0003682", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003682", "evidence": [ { "database": "UniProtKB", "id": "F6R6E5", "url": "https://www.uniprot.org/uniprotkb/F6R6E5" } ], "pmid": "" }, { "name": "ubiquitin protein ligase binding", "id": "GO:0031625", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0031625", "evidence": [ { "database": "UniProtKB", "id": "F6R6E5", "url": "https://www.uniprot.org/uniprotkb/F6R6E5" } ], "pmid": "" }, { "name": "proline-rich region binding", "id": "GO:0070064", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0070064", "evidence": [ { "database": "UniProtKB", "id": "F6R6E5", "url": "https://www.uniprot.org/uniprotkb/F6R6E5" } ], "pmid": "" }, { "name": "histone binding", "id": "GO:0042393", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0042393", "evidence": [ { "database": "UniProtKB", "id": "F6R6E5", "url": "https://www.uniprot.org/uniprotkb/F6R6E5" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 6, "go_terms": [ { "name": "negative regulation of transcription by RNA polymerase II", "id": "GO:0000122", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000122", "evidence": [ { "database": "UniProtKB", "id": "F6R6E5", "url": "https://www.uniprot.org/uniprotkb/F6R6E5" } ], "pmid": "" }, { "name": "positive regulation of neuron projection development", "id": "GO:0010976", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0010976", "evidence": [ { "database": "UniProtKB", "id": "F6R6E5", "url": "https://www.uniprot.org/uniprotkb/F6R6E5" } ], "pmid": "" }, { "name": "positive regulation of apoptotic process", "id": "GO:0043065", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0043065", "evidence": [ { "database": "UniProtKB", "id": "F6R6E5", "url": "https://www.uniprot.org/uniprotkb/F6R6E5" } ], "pmid": "" }, { "name": "regulation of DNA-templated transcription", "id": "GO:0006355", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006355", "evidence": [ { "database": "UniProtKB", "id": "F6R6E5", "url": "https://www.uniprot.org/uniprotkb/F6R6E5" } ], "pmid": "" }, { "name": "DNA damage response", "id": "GO:0006974", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006974", "evidence": [ { "database": "UniProtKB", "id": "F6R6E5", "url": "https://www.uniprot.org/uniprotkb/F6R6E5" } ], "pmid": "" }, { "name": "positive regulation of DNA-templated transcription", "id": "GO:0045893", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0045893", "evidence": [ { "database": "UniProtKB", "id": "F6R6E5", "url": "https://www.uniprot.org/uniprotkb/F6R6E5" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 90, "end_pos": 92, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "F6R6E5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F6R6E5" }, { "id": "PS01179", "database": "PROSITE", "url": "https://prosite.expasy.org/PS01179" } ], "ann_type": "Domain_Extent_Annotation", 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"field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", 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"graph_view": "yes" } }, { "uniprot_canonical_ac": "F1N3E3-1", "uniprot_ac": "F1N3E3", "uniprot_id": "F1N3E3_BOVIN", "mass": { "chemical_mass": 99293.0, "monoisotopic_mass": 99293.0 }, "refseq": { "ac": "XP_005207864", "name": "serine-rich coiled-coil domain-containing protein 1 isoform X1", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_005207864" }, "gene_names": [ { "name": "CCSER1", "type": "recommended", "evidence": [ { "id": "F1N3E3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1N3E3" } ] }, { "name": "CCSER1", "type": "synonym", "evidence": [ { "id": "XP_005207864", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_005207864" } ] }, { "name": "FAM190A", "type": "synonym", "evidence": [ { "id": "XP_005207864", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_005207864" } ] } ], "protein_names": [ { "name": "Coiled-coil serine rich protein 1", "type": "synonym", "evidence": [ { "id": "F1N3E3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1N3E3/entry#names_and_taxonomy" } ] }, { "name": "serine-rich coiled-coil domain-containing protein 1 isoform X1", "type": "synonym", "evidence": [ { "id": "XP_005207864", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_005207864" } ] } ], "function": [], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Bos taurus", "taxid": 9913, "evidence": [ { "database": "UniProtKB", "id": "F1N3E3", "url": "https://www.uniprot.org/uniprotkb/F1N3E3" } ], "common_name": "Bovine", "glygen_name": "Bovine", "reference_species": "Bos taurus [9913]" } ], "gene": [ { "name": "CCSER1", "url": "https://www.uniprot.org/uniprotkb/F1N3E3", "locus": { "chromosome": "6", "start_pos": 33015656, "end_pos": 34501208, "strand": "+", "evidence": [ { "database": "Ensembl Gene", "id": "ENSBTAG00000019808", "url": "https://www.ensembl.org/id/ENSBTAG00000019808" } ] } } ], "crossref": [ { "id": "F1N3E3", "url": "https://alphafold.ebi.ac.uk/entry/F1N3E3", "database": "AlphaFoldDB", "categories": [] }, { "id": "ENSBTAG00000019808", "url": "https://bgee.org/?page=gene&gene_id=ENSBTAG00000019808", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "616908", "url": "https://www.ncbi.nlm.nih.gov/gene/616908", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR029627", "url": "https://www.ebi.ac.uk/interpro/entry/IPR029627", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "PTHR22461", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR22461", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR22461:SF1", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR22461:SF1", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "XP_005207864", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_005207864", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A3Q1M6K9", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1M6K9", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A3Q1M6K9-1", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1M6K9-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A3Q1M8Q0", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1M8Q0", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A3Q1M8Q0-1", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1M8Q0-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "F1N3E3", "url": "https://www.uniprot.org/uniprotkb/F1N3E3", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "F1N3E3-1", "url": "https://www.uniprot.org/uniprotkb/F1N3E3-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MGDSGSRRSTLVSRLPIFRRSISRKHDSLPSSPSSSNTVGVHSSSPSSTNSSSGSTGKRRSLFRTPSISFHHKKGSEPKQEPTNQNLSISNGAQPGQSSMQKLSLEEHTKARGRHSVGFSSSRNKKITRSLTEDFEREKEHSTNKNVFINCLSSGKSEGDDSGFTEEQTRRSVKQSTKKLLTKSFSSHYKLSKPVPQSQSISLVQQSEFSLEITQYQEREPVLVRGSPSCSVDVTERAGSSLQSPLLSADLTTAQTPSEFLALTEDSVSETDAFPKSGSMASHCDNLGHNDSTSQISPNPAAVTKTTRDLRGTVPCAIVSPGKYRLEGRCSTESNSLPETSAAYQKEVLLQITKLPVMNGSDSETHLSTDTREDHIVIQNGETMLATSSPRKFGFYEHHKAIAERVKGIHPISDSRIIPSSGDHHVLNKTSYGYDANPAKVLASSLSPYREGRFIERRLRSSSEGTAGSSRMILKPKDGNVEEVNSLRKQRASSSSSKMNSMDVLNNLGSCELDEDDLMLDLEFLEEQNLHPSVCREDSYHSVVSCAAVVLTPMEPTVEMKKREELKFREPSKQNLSLKLAKDIDQEARCSHIRGVPSSPSSDWPLPSVEENGGIDSLPFRLMLQDCTAVKTLLLKMKRVLQESADMSPASSTTSLPVSPLAEEPLPFKDIMKDECSMLKLQLKEKDELISQLQEELEKVQHLQKAFASRVDKSTQTELLGYDGLNLKRLESVQGGREATYRNRIVSQNLSTRDRKIMHTPTEDHFRSPAADQTSPYKSKACQLPSLCLSSLLKDKELVEVIKHSRGTYETLTSEVTQNLRATVGQNSMKPTAKTEGLATFSEKPKDQAAAARQHSTFTGRFGQPPRGPISLHMYSRKNVFLHHNLHTTELQTLGQQDG", "length": 899, "header": "tr|F1N3E3-1|F1N3E3_BOVIN Isoform 1 of Coiled-coil serine rich protein 1 OS=Bos taurus OX=9913 GN=CCSER1 PE=3 SV=4 CANONICAL=F1N3E3-1" }, "isoforms": [ { "isoform_ac": "A0A3Q1M6K9-1", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1M6K9/entry", "sequence": { "sequence": "MGDSGSRRSTLVSRLPIFRRSISRKHDSLPSSPSSSNTVGVHSSSPSSTNSSSGSTGKRRSLFRTPSISFHHKKGSEPKQEPTNQNLSISNGAQPGQSSMQKLSLEEHTKARGRHSVGFSSSRNKKITRSLTEDFEREKEHSTNKNVFINCLSSGKSEGDDSGFTEEQTRRSVKQSTKKLLTKSFSSHYKLSKPVPQSQSISLVQQSEFSLEITQYQEREPVLVRGSPSCSVDVTERAGSSLQSPLLSADLTTAQTPSEFLALTEDSVSETDAFPKSGSMASHCDNLGHNDSTSQISPNPAAVTKTTRDLRGTVPCAIVSPGKYRLEGRCSTESNSLPETSAAYQKEVLLQITKLPVMNGSDSETHLSTDTREDHIVIQNGETMLATSSPRKFGFYEHHKAIAERVKGIHPISDSRIIPSSGDHHVLNKTSYGYDANPAKVLASSLSPYREGRFIERRLRSSSEGTAGSSRMILKPKDGNVEEVNSLRKQRASSSSSKMNSMDVLNNLGSCELDEDDLMLDLEFLEEQNLHPSVCREDSYHSVVSCAAVVLTPMEPTVEMKKREELKFREPSKQNLSLKLAKDIDQEARCSHIRGVPSSPSSDWPLPSVEENGGIDSLPFRLMLQDCTAVKTLLLKMKRVLQESADMSPASSTTSLPVSPLAEEPLPFKDIMKDECSMLKLQLKEKDELISQLQEELEKVQHLQKAFASRVDKSTQTELLGYDALWNPTCTEGLFKPVHNIST", "length": 743, "header": "tr|A0A3Q1M6K9-1|F1N3E3_BOVIN Computationally mapped isoform of Coiled-coil serine rich protein 1 OS=Bos taurus OX=9913 GN=CCSER1 PE=3 SV=1 CANONICAL=F1N3E3-1" }, "locus": { "chromosome": "6", "start_pos": 34329203, "end_pos": 33664576, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000072071.1", "url": "https://www.ensembl.org/id/ENSBTAT00000072071.1" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000063949.1", "url": "https://www.ensembl.org/id/ENSBTAP00000063949.1" } ] } }, { "isoform_ac": "A0A3Q1M8Q0-1", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1M8Q0/entry", "sequence": { "sequence": "MGDSGSRRSTLVSRLPIFRRSISRKHDSLPSSPSSSNTVGVHSSSPSSTNSSSGSTGKRRSLFRTPSISFHHKKGSEPKQEPTNQNLSISNGAQPGQSSMQKLSLEEHTKARGRHSVGFSSSRNKKITRSLTEDFEREKEHSTNKNVFINCLSSGKSEGDDSGFTEEQTRRSVKQSTKKLLTKSFSSHYKLSKPVPQSQSISLVQQSEFSLEITQYQEREPVLVRGSPSCSVDVTERAGSSLQSPLLSADLTTAQTPSEFLALTEDSVSETDAFPKSGSMASHCDNLGHNDSTSQISPNPAAVTKTTRDLRGTVPCAIVSPGKYRLEGRCSTESNSLPETSAAYQKEVLLQITKLPVMNGSDSETHLSTDTREDHIVIQNGETMLATSSPRKFGFYEHHKAIAERVKGIHPISDSRIIPSSGDHHVLNKTSYGYDANPAKVLASSLSPYREGRFIERRLRSSSEGTAGSSRMILKPKDGNVEEVNSLRKQRASSSSSKMNSMDVLNNLGSCELDEDDLMLDLEFLEEQNLHPSVCREDSYHSVVSCAAVVLTPMEPTVEMKKREELKFREPSKQNLSLKLAKDIDQEARCSHIRGVPSSPSSDWPLPSVEENGGIDSLPFRLMLQDCTAVKTLLLKMKRVLQEFLLACLFIGHWEIHICITWQICELILIVQGV", "length": 674, "header": "tr|A0A3Q1M8Q0-1|F1N3E3_BOVIN Computationally mapped isoform of Coiled-coil serine rich protein 1 OS=Bos taurus OX=9913 GN=CCSER1 PE=3 SV=1 CANONICAL=F1N3E3-1" }, "locus": { "chromosome": "6", "start_pos": 34329203, "end_pos": 33969191, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000072807.2", "url": "https://www.ensembl.org/id/ENSBTAT00000072807.2" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000070304.1", "url": "https://www.ensembl.org/id/ENSBTAP00000070304.1" } ] } }, { "isoform_ac": "F1N3E3-1", "url": "https://www.uniprot.org/uniprotkb/F1N3E3/entry", "sequence": { "sequence": "MGDSGSRRSTLVSRLPIFRRSISRKHDSLPSSPSSSNTVGVHSSSPSSTNSSSGSTGKRRSLFRTPSISFHHKKGSEPKQEPTNQNLSISNGAQPGQSSMQKLSLEEHTKARGRHSVGFSSSRNKKITRSLTEDFEREKEHSTNKNVFINCLSSGKSEGDDSGFTEEQTRRSVKQSTKKLLTKSFSSHYKLSKPVPQSQSISLVQQSEFSLEITQYQEREPVLVRGSPSCSVDVTERAGSSLQSPLLSADLTTAQTPSEFLALTEDSVSETDAFPKSGSMASHCDNLGHNDSTSQISPNPAAVTKTTRDLRGTVPCAIVSPGKYRLEGRCSTESNSLPETSAAYQKEVLLQITKLPVMNGSDSETHLSTDTREDHIVIQNGETMLATSSPRKFGFYEHHKAIAERVKGIHPISDSRIIPSSGDHHVLNKTSYGYDANPAKVLASSLSPYREGRFIERRLRSSSEGTAGSSRMILKPKDGNVEEVNSLRKQRASSSSSKMNSMDVLNNLGSCELDEDDLMLDLEFLEEQNLHPSVCREDSYHSVVSCAAVVLTPMEPTVEMKKREELKFREPSKQNLSLKLAKDIDQEARCSHIRGVPSSPSSDWPLPSVEENGGIDSLPFRLMLQDCTAVKTLLLKMKRVLQESADMSPASSTTSLPVSPLAEEPLPFKDIMKDECSMLKLQLKEKDELISQLQEELEKVQHLQKAFASRVDKSTQTELLGYDGLNLKRLESVQGGREATYRNRIVSQNLSTRDRKIMHTPTEDHFRSPAADQTSPYKSKACQLPSLCLSSLLKDKELVEVIKHSRGTYETLTSEVTQNLRATVGQNSMKPTAKTEGLATFSEKPKDQAAAARQHSTFTGRFGQPPRGPISLHMYSRKNVFLHHNLHTTELQTLGQQDG", "length": 899, "header": "tr|F1N3E3-1|F1N3E3_BOVIN Isoform 1 of Coiled-coil serine rich protein 1 OS=Bos taurus OX=9913 GN=CCSER1 PE=3 SV=4 CANONICAL=F1N3E3-1" }, "locus": { "chromosome": "6", "start_pos": 34329203, "end_pos": 33015659, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000026390.7", "url": "https://www.ensembl.org/id/ENSBTAT00000026390.7" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000026390.7", "url": "https://www.ensembl.org/id/ENSBTAP00000026390.7" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [], "orthologs": [], "go_annotation": {}, "pro_annotation": [], "site_annotation": [ { "start_pos": 290, "end_pos": 292, "annotation": "n_glycosylation_sequon" }, { "start_pos": 359, "end_pos": 361, "annotation": "n_glycosylation_sequon" }, { "start_pos": 428, "end_pos": 430, "annotation": "n_glycosylation_sequon" }, { "start_pos": 50, "end_pos": 52, "annotation": "n_glycosylation_sequon" }, { "start_pos": 575, "end_pos": 577, "annotation": "n_glycosylation_sequon" }, { "start_pos": 749, "end_pos": 751, "annotation": "n_glycosylation_sequon" }, { "start_pos": 86, "end_pos": 88, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [ { "pdb_id": "AF-F1N3E3-F1", "pdb_chain": "global", "start_pos": 1, "end_pos": 899, "overlap": "1.0", "method": "AlphaFold", "type": "alphafold", "resolution": -1.0, "url": "https://data.glygen.org/ln2downloads/pdb/current/AF-F1N3E3-F1.pdb", "url_external": "https://alphafold.ebi.ac.uk/entry/F1N3E3" } ], "lectin_list": [], "domain_list": [], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 290, "end_pos": 292 }, { "start_pos": 359, "end_pos": 361 }, { "start_pos": 428, "end_pos": 430 }, { "start_pos": 50, "end_pos": 52 }, { "start_pos": 575, "end_pos": 577 }, { "start_pos": 749, "end_pos": 751 }, { "start_pos": 86, "end_pos": 88 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ], "tool_support": { "graph_view": "yes" } }, { "uniprot_canonical_ac": "F6Q1G9-1", "uniprot_ac": "F6Q1G9", "uniprot_id": "F6Q1G9_BOVIN", "mass": { "chemical_mass": 26457.0, "monoisotopic_mass": 26457.0 }, "refseq": {}, "gene_names": [ { "name": "RAB24", "type": "recommended", "evidence": [ { "id": "F6Q1G9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F6Q1G9" } ] } ], "protein_names": [ { "name": "Ras-related protein Rab-24", "type": "recommended", "evidence": [ { "id": "F6Q1G9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F6Q1G9/entry#names_and_taxonomy" } ] }, { "name": "3.6.5.2", "type": "synonym", "evidence": [ { "id": "F6Q1G9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F6Q1G9/entry#names_and_taxonomy" } ] } ], "function": [ { "annotation": "The small GTPases Rab are key regulators of intracellular membrane trafficking, from the formation of transport vesicles to their fusion with membranes. Rabs cycle between an inactive GDP-bound form and an active GTP-bound form that is able to recruit to membranes different sets of downstream effectors directly responsible for vesicle formation, movement, tethering and fusion. RAB24 is an atypical RAB protein that presents low GTPase activity and thereby exists predominantly in the GTP-bound active state. RAB24 is required for the clearance of late autophagic vacuoles under basal conditions. It is not needed for starvation-induced autophagy. Involved in the modulation of meiotic apparatus assembly and meiotic progression during oocyte maturation, possibly through regulation of kinetochore-microtubule interaction.", "evidence": [ { "database": "UniProtKB", "id": "A0A3Q1M6P8", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1M6P8#function" }, { "database": "UniProtKB", "id": "ARBA00093319", "url": "https://www.uniprot.org/uniprotkb/ARBA00093319#function" }, { "database": "UniProtKB", "id": "E1B771", "url": "https://www.uniprot.org/uniprotkb/E1B771#function" }, { "database": "UniProtKB", "id": "F6Q1G9", "url": "https://www.uniprot.org/uniprotkb/F6Q1G9#function" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Bos taurus", "taxid": 9913, "evidence": [ { "database": "UniProtKB", "id": "F6Q1G9", "url": "https://www.uniprot.org/uniprotkb/F6Q1G9" } ], "common_name": "Bovine", "glygen_name": "Bovine", "reference_species": "Bos taurus [9913]" } ], "gene": [ { "name": "RAB24", "url": "https://www.uniprot.org/uniprotkb/F6Q1G9", "locus": { "chromosome": "7", "start_pos": 38769714, "end_pos": 38775449, "strand": "+", "evidence": [ { "database": "Ensembl Gene", "id": "ENSBTAG00000025425", "url": "https://www.ensembl.org/id/ENSBTAG00000025425" } ] } } ], "crossref": [ { "id": "F6Q1G9", "url": "https://alphafold.ebi.ac.uk/entry/F6Q1G9", "database": "AlphaFoldDB", "categories": [] }, { "id": "ENSBTAG00000025425", "url": "https://bgee.org/?page=gene&gene_id=ENSBTAG00000025425", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "cd04118", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd04118", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "617635", "url": "https://www.ncbi.nlm.nih.gov/gene/617635", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR001806", "url": "https://www.ebi.ac.uk/interpro/entry/IPR001806", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR005225", "url": "https://www.ebi.ac.uk/interpro/entry/IPR005225", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR027417", "url": "https://www.ebi.ac.uk/interpro/entry/IPR027417", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR041828", "url": "https://www.ebi.ac.uk/interpro/entry/IPR041828", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "RFRAGPY", "url": "https://omabrowser.org/oma/group/RFRAGPY/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "A0A3Q1M6P8", "url": "https://www.orthodb.org/?gene=A0A3Q1M6P8", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "E1B771", "url": "https://www.orthodb.org/?gene=E1B771", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR47978", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR47978", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00071", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00071", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "19669", "url": "https://www.rhea-db.org/rhea/19669", "database": "Rhea", "categories": [ "Enzyme and Pathway" ] }, { "id": "A0A3Q1M6P8", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1M6P8", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A3Q1M6P8-1", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1M6P8-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "E1B771", "url": "https://www.uniprot.org/uniprotkb/E1B771", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "E1B771-1", "url": "https://www.uniprot.org/uniprotkb/E1B771-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "F6Q1G9", "url": "https://www.uniprot.org/uniprotkb/F6Q1G9", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "F6Q1G9-1", "url": "https://www.uniprot.org/uniprotkb/F6Q1G9-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MSGQRVDVKVVMLGKEYVGKTSLVERYVHDRFLVGPYQNTIGAAFVAKVMSVGDRTVTLGIWDTAGSERYEAMSRIYYRGAKAAIVCYDLTDSSSFERAKFWVKELRNQEEGCQIYLCGTKSDLLEEDRRRRRVDFHDVQDYADNIKAQLFETSSKTGQSVDELFQKVAEDYVSVAAFQVMTGEAARTNFLPATLFLMRQRASPAPVSRCCQAWKRIADALHALTVVWGGECKE", "length": 234, "header": "tr|F6Q1G9-1|F6Q1G9_BOVIN Isoform 1 of Ras-related protein Rab-24 OS=Bos taurus OX=9913 GN=RAB24 PE=3 SV=1 CANONICAL=F6Q1G9-1" }, "isoforms": [ { "isoform_ac": "A0A3Q1M6P8-1", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1M6P8/entry", "sequence": { "sequence": "MSGQRVDVKVVMLGKEYVGKTSLVERYVHDRFLVGPYQNTIGAAFVAKVMSVGDRTVTLGIWDTAGSERYEAMSRIYYRGAKAAIVCYDLTDSSSFERAKFWVKELRNQEEGCQIYLCGTKSDLLEEDRRRRRVDFHDVQDYADNELFQKVAEDYVSVAAFQVMTGEAARTNFLPATLFLMRQRASPAPVSRCCQAWKRIADALHALTVVWGGECKE", "length": 217, "header": "tr|A0A3Q1M6P8-1|F6Q1G9_BOVIN Computationally mapped isoform of Ras-related protein Rab-24 OS=Bos taurus OX=9913 GN=RAB24 PE=3 SV=2 CANONICAL=F6Q1G9-1" }, "locus": { "chromosome": "7", "start_pos": 38775384, "end_pos": 38770718, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000073240.2", "url": "https://www.ensembl.org/id/ENSBTAT00000073240.2" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000065685.2", "url": "https://www.ensembl.org/id/ENSBTAP00000065685.2" } ] } }, { "isoform_ac": "E1B771-1", "url": "https://www.uniprot.org/uniprotkb/E1B771/entry", "sequence": { "sequence": "MSGQRVDVKVVMLGKEYVGKTSLVERYVHDRFLVGPYQNTIGAAFVAKVMSVGDRTVTLGIWDTAGSERYEAMSRIYYRGAKAAIVCYDLTDSSSFERAKFWVKELRNQEEGCQIYLCGTKSDLLEEDRRRRRVDFHDVQDYADNIKAQLFETSSKTGQSVDELFQKVAEDYVSVAAFQVMTEDKGVDLGQKANPYFYSCCHH", "length": 203, "header": "tr|E1B771-1|E1B771_BOVIN Computationally mapped isoform of Ras-related protein Rab-24 OS=Bos taurus OX=9913 GN=RAB24 PE=3 SV=3 CANONICAL=F6Q1G9-1" }, "locus": { "chromosome": "7", "start_pos": 38775384, "end_pos": 38773832, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000054760.3", "url": "https://www.ensembl.org/id/ENSBTAT00000054760.3" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000051902.3", "url": "https://www.ensembl.org/id/ENSBTAP00000051902.3" } ] } }, { "isoform_ac": "F6Q1G9-1", "url": "https://www.uniprot.org/uniprotkb/F6Q1G9/entry", "sequence": { "sequence": "MSGQRVDVKVVMLGKEYVGKTSLVERYVHDRFLVGPYQNTIGAAFVAKVMSVGDRTVTLGIWDTAGSERYEAMSRIYYRGAKAAIVCYDLTDSSSFERAKFWVKELRNQEEGCQIYLCGTKSDLLEEDRRRRRVDFHDVQDYADNIKAQLFETSSKTGQSVDELFQKVAEDYVSVAAFQVMTGEAARTNFLPATLFLMRQRASPAPVSRCCQAWKRIADALHALTVVWGGECKE", "length": 234, "header": "tr|F6Q1G9-1|F6Q1G9_BOVIN Isoform 1 of Ras-related protein Rab-24 OS=Bos taurus OX=9913 GN=RAB24 PE=3 SV=1 CANONICAL=F6Q1G9-1" }, "locus": { "chromosome": "7", "start_pos": 38775384, "end_pos": 38770718, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000035714.4", "url": "https://www.ensembl.org/id/ENSBTAT00000035714.4" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000035584.3", "url": "https://www.ensembl.org/id/ENSBTAP00000035584.3" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [ "enzyme" ], "publication": [], "pathway": [], "orthologs": [ { "uniprot_canonical_ac": "A0A096MKB0-1", "protein_name": "Ras-related protein Rab-24", "gene_name": "Rab24", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MSGQRVDVKVVMLGKEYVGKTSLVERYVHDRFLVGPYQNTIGAAFVAKVMCVGDRTVTLGIWDTAGSERYEAMSRIYYRGAKAAIVCYDLTDSSSFERAKFWVKELRSLEEGCQIYLCGTKSDLLEEDRRRRRVDFHDVQDYADNIKAQLFETSSKTGQSVDELFQKVAEDYVSVAAFQVMTAVVTTESQLICPVELDELPEGLDPTLVWAGVVKRLSYSRCPLQQRWHLPVLARGTEAVLG", "length": 242 }, "evidence": [ { "id": "F6Q1G9", "url": "https://omabrowser.org/oma/group/F6Q1G9/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "A0A8V0Y4A4-1", "protein_name": "Ras-related protein Rab-24", "gene_name": "RAB24", "tax_id": 9031, "organism": "Gallus gallus", "sequence": { "sequence": "DGPLRVPRWSPGRVSQGLPAVRSRPPSSPPCPRAVPPGLGPRGVPTAPLSPRSSLYPHIPHVALPSPERLPHIRRPNVPHASVPASSCPITSPARGLPRVPISDPSVPPLGPTVPPPLPLQTIGAAFVAKVLSVGEQTVTLGIWDTAGSERYEAMSRIYYRGARAAIVCYDLTNSSSFQRAKFWVNELQNCEEGCRIYLCGTKSDLLEEDRRKRDVDFHDVQDYADEVKAELFETSSKTGQNVDELFQKVAEDYVHFTAFQEMTEEKGVDLGQKSSSYLYSCCHH", "length": 285 }, "evidence": [ { "id": "F6Q1G9", "url": "https://omabrowser.org/oma/group/F6Q1G9/", "database": "OMA" } ], "glygen_name": "Chicken", "common_name": "Chicken" }, { "uniprot_canonical_ac": "P35290-1", "protein_name": "Ras-related protein Rab-24", "gene_name": "Rab24", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MSGQRVDVKVVMLGKEYVGKTSLVERYVHDRFLVGPYQNTIGAAFVAKVMCVGDRTVTLGIWDTAGSERYEAMSRIYYRGAKAAIVCYDLTDSSSFERAKFWVKELRSLEEGCQIYLCGTKSDLLEEDRRRRRVDFHDVQDYADNIKAQLFETSSKTGQSVDELFQKVAEDYVSVAAFQVMTEDKGVDLSQKANPYFYSCCHH", "length": 203 }, "evidence": [ { "id": "F6Q1G9", "url": "https://omabrowser.org/oma/group/F6Q1G9/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q55FU9-1", "protein_name": "Ras-related protein Rab-24", "gene_name": "rab24", "tax_id": 44689, "organism": "Dictyostelium discoideum", "sequence": { "sequence": "MTKTKIDLKVVLLGYASVGKTCIVTRYTSGQFGDTHTTIGGAFSSKRVVVGETEVLLGIWDTAGTERYQAVNVSYYRRANAAIVCYDLTNRESWEKVTFWAEELTQNEPEIEIYIVGTKLDLIQQGDIKAVPEEEVKQTARRYKAHIFETSSRTGENVSLLFQTIAEDFCKRTNNGTNPVNSNPSNVVNVNTQTQKKKGGCC", "length": 202 }, "evidence": [ { "id": "F6Q1G9", "url": "https://omabrowser.org/oma/group/F6Q1G9/", "database": "OMA" } ], "glygen_name": "Cellular slime mold", "common_name": "Social amoeba" }, { "uniprot_canonical_ac": "Q969Q5-1", "protein_name": "Ras-related protein Rab-24", "gene_name": "RAB24", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MSGQRVDVKVVMLGKEYVGKTSLVERYVHDRFLVGPYQNTIGAAFVAKVMSVGDRTVTLGIWDTAGSERYEAMSRIYYRGAKAAIVCYDLTDSSSFERAKFWVKELRSLEEGCQIYLCGTKSDLLEEDRRRRRVDFHDVQDYADNIKAQLFETSSKTGQSVDELFQKVAEDYVSVAAFQVMTEDKGVDLGQKPNPYFYSCCHH", "length": 203 }, "evidence": [ { "id": "F6Q1G9", "url": "https://omabrowser.org/oma/group/F6Q1G9/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" } ], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 6, "go_terms": [ { "name": "autophagosome membrane", "id": "GO:0000421", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000421", "evidence": [ { "database": "UniProtKB", "id": "F6Q1G9", "url": "https://www.uniprot.org/uniprotkb/F6Q1G9" } ], "pmid": "" }, { "name": "spindle", "id": "GO:0005819", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005819", "evidence": [ { "database": "UniProtKB", "id": "F6Q1G9", "url": "https://www.uniprot.org/uniprotkb/F6Q1G9" } ], "pmid": "" }, { "name": "cytosol", "id": "GO:0005829", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005829", "evidence": [ { "database": "UniProtKB", "id": "F6Q1G9", "url": "https://www.uniprot.org/uniprotkb/F6Q1G9" } ], "pmid": "" }, { "name": "perinuclear region of cytoplasm", "id": "GO:0048471", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0048471", "evidence": [ { "database": "UniProtKB", "id": "F6Q1G9", "url": "https://www.uniprot.org/uniprotkb/F6Q1G9" } ], "pmid": "" }, { "name": "endomembrane system", "id": "GO:0012505", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0012505", "evidence": [ { "database": "UniProtKB", "id": "F6Q1G9", "url": "https://www.uniprot.org/uniprotkb/F6Q1G9" } ], "pmid": "" }, { "name": "cytoplasmic vesicle", "id": "GO:0031410", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0031410", "evidence": [ { "database": "UniProtKB", "id": "F6Q1G9", "url": "https://www.uniprot.org/uniprotkb/F6Q1G9" } ], "pmid": "" } ] }, { "name": "Molecular Function", "total": 4, "go_terms": [ { "name": "GTP binding", "id": "GO:0005525", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005525", "evidence": [ { "database": "UniProtKB", "id": "F6Q1G9", "url": "https://www.uniprot.org/uniprotkb/F6Q1G9" } ], "pmid": "" }, { "name": "metal ion binding", "id": "GO:0046872", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0046872", "evidence": [ { "database": "UniProtKB", "id": "F6Q1G9", "url": "https://www.uniprot.org/uniprotkb/F6Q1G9" } ], "pmid": "" }, { "name": "G protein activity", "id": "GO:0003925", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003925", "evidence": [ { "database": "UniProtKB", "id": "F6Q1G9", "url": "https://www.uniprot.org/uniprotkb/F6Q1G9" } ], "pmid": "" }, { "name": "GTPase activity", "id": "GO:0003924", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003924", "evidence": [ { "database": "UniProtKB", "id": "F6Q1G9", "url": "https://www.uniprot.org/uniprotkb/F6Q1G9" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 5, "go_terms": [ { "name": "protein transport", "id": "GO:0015031", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0015031", "evidence": [ { "database": "UniProtKB", "id": "F6Q1G9", "url": "https://www.uniprot.org/uniprotkb/F6Q1G9" } ], "pmid": "" }, { "name": "autophagy", "id": "GO:0006914", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006914", "evidence": [ { "database": "UniProtKB", "id": "F6Q1G9", "url": "https://www.uniprot.org/uniprotkb/F6Q1G9" } ], "pmid": "" }, { "name": "attachment of spindle microtubules to kinetochore", "id": "GO:0008608", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008608", "evidence": [ { "database": "UniProtKB", "id": "F6Q1G9", "url": "https://www.uniprot.org/uniprotkb/F6Q1G9" } ], "pmid": "" }, { "name": "oocyte maturation", "id": "GO:0001556", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0001556", "evidence": [ { "database": "UniProtKB", "id": "F6Q1G9", "url": "https://www.uniprot.org/uniprotkb/F6Q1G9" } ], "pmid": "" }, { "name": "meiotic nuclear division", "id": "GO:0140013", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0140013", "evidence": [ { "database": "UniProtKB", "id": "F6Q1G9", "url": "https://www.uniprot.org/uniprotkb/F6Q1G9" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [], "ptm_annotation": [], "interactions": [], "reactions": [ { "id": "19669", "name": "", "equation": "GTP + H2O = GDP + phosphate + H(+)", "summary": "", "cellular_location": "", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [ "Q08E00-1", "Q5E9J3-1", "A6QP66-1", "Q2KHU8-1", "Q2KIA5-1", "F1MM29-1", "P08239-1", "P04896-1", "P63097-1", "Q7YS69-1", "Q0VCJ7-1", "A0AAA9SVR8-1", "P81948-1", "Q2KJ93-1", "A0AAA9TES1-1", "P61223-1", "Q2HJB8-1", "Q0IIG7-1", "Q3ZCJ7-1", "Q27957-1", "Q2HJ86-1", "A0A3Q1LMP2-1", "F1MB25-1", "Q58DS9-1", "A0AAA9S306-1", "A0A3Q1NEF8-1", "A4FV54-1", "A6H7I5-1", "F2Z4D5-1", "G3N1U2-1", "O18956-1", "P62998-1", "Q32KN8-1", "Q3MHP2-1", "Q3T054-1", "Q3T0F5-1", "Q3T0T7-1", "Q56JV3-1", "F1MNI4-1", "Q8HZJ5-1", "P61585-1", "P62833-1", "P68103-1", "Q08DI5-1", "Q2HJH2-1", "Q2T9U1-1", "Q2TBH7-1", "Q3MHP5-1", "Q3SX43-1", "Q3SYU2-1", "P81947-1", "P84080-1", "Q08DF4-1", "Q2KI07-1", "Q2TA29-1", "Q3T0D7-1", "A6QLJ3-1", "A6QNM2-1", "A6QR46-1", "Q1LZ78-1", "Q2KHZ2-1", "G3MYK6-1", "Q58D56-1", "Q32KW9-1", "P11023-1", "Q58DW6-1", "Q9TU25-1", "P10948-1", "Q2HJI8-1", "P10949-1", "Q0IIG8-1", "Q29RR0-1", "Q32PH8-1", "Q58DS5-1", "Q1RMR4-1", "Q3ZC27-1", "P49410-1", "A0A140T898-1", "E1BPU0-1", "A0AAA9S5W8-1", "A0AAA9SLN0-1", "A0AAF6Z672-1", "Q17R06-1", "Q58D72-1", "P82922-1", "Q2HJF8-1", "Q17QU4-1", "Q2YDM7-1", "A0AAA9T9T1-1", "A0A3Q1MDX0-1", "F1N2J9-1", "Q17QB7-1", "Q3SWY9-1", "Q5E9M9-1", "A0A3S5ZPA2-1", "A0AAA9SV95-1", "A0AAA9TWE6-1", "F1N6Y7-1", "F1N7V2-1", "A0AAA9SGM6-1", "A0AAA9TNQ2-1", "A0AAA9TS74-1", "F6Q1G9-1", "A0AAF6YXF5-1", "A5D7J5-1", "P04695-1", "Q3ZBW5-1", "A4FUD1-1", "A0A3Q1M0B9-1", "A6H7F2-1", "F1MHP4-1", "A0A3Q1MGR4-1", "A0A3Q1NCE9-1", "Q0P5E2-1", "Q32LJ6-1", "Q58DC5-1", "Q08DA0-1", "A0ABI0NND0-1", 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"isoformset.uniprotkb", "label": "Isoforms" }, { "name": "homologset.oma", "label": "OMA Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ], "tool_support": { "graph_view": "yes" } }, { "uniprot_canonical_ac": "F1N3G1-1", "uniprot_ac": "F1N3G1", "uniprot_id": "F1N3G1_BOVIN", "mass": { "chemical_mass": 91486.0, "monoisotopic_mass": 91486.0 }, "refseq": {}, "gene_names": [ { "name": "PTPDC1", "type": "recommended", "evidence": [ { "id": "F1N3G1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1N3G1" } ] } ], "protein_names": [ { "name": "Protein tyrosine phosphatase domain-containing protein 1", "type": "recommended", "evidence": [ { "id": "F1N3G1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1N3G1/entry#names_and_taxonomy" } ] } ], "function": [ { "annotation": "May play roles in cilia formation and/or maintenance.", "evidence": [ { "database": "UniProtKB", "id": "A0A3Q1M6Q3", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1M6Q3#function" }, { "database": "UniProtKB", "id": "ARBA00056295", "url": "https://www.uniprot.org/uniprotkb/ARBA00056295#function" }, { "database": "UniProtKB", "id": "F1N3G1", "url": "https://www.uniprot.org/uniprotkb/F1N3G1#function" }, { "database": "UniProtKB", "id": "A0ABI0NYD3", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NYD3#function" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Bos taurus", "taxid": 9913, "evidence": [ { "database": "UniProtKB", "id": "F1N3G1", "url": "https://www.uniprot.org/uniprotkb/F1N3G1" } ], "common_name": "Bovine", "glygen_name": "Bovine", "reference_species": "Bos taurus [9913]" } ], "gene": [ { "name": "PTPDC1", "url": "https://www.uniprot.org/uniprotkb/F1N3G1", "locus": { "chromosome": "8", "start_pos": 85382672, "end_pos": 85312669, "strand": "-", "evidence": [ { "database": "Ensembl Gene", "id": "ENSBTAG00000005803", "url": "https://www.ensembl.org/id/ENSBTAG00000005803" } ] } } ], "crossref": [ { "id": "F1N3G1", "url": "https://alphafold.ebi.ac.uk/entry/F1N3G1", "database": "AlphaFoldDB", "categories": [] }, { "id": "ENSBTAG00000005803", "url": "https://bgee.org/?page=gene&gene_id=ENSBTAG00000005803", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "cd14506", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd14506", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "519311", "url": "https://www.ncbi.nlm.nih.gov/gene/519311", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR000340", "url": "https://www.ebi.ac.uk/interpro/entry/IPR000340", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR000387", "url": "https://www.ebi.ac.uk/interpro/entry/IPR000387", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR003595", "url": "https://www.ebi.ac.uk/interpro/entry/IPR003595", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR016130", "url": "https://www.ebi.ac.uk/interpro/entry/IPR016130", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR020422", "url": "https://www.ebi.ac.uk/interpro/entry/IPR020422", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR029021", "url": "https://www.ebi.ac.uk/interpro/entry/IPR029021", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR049573", "url": "https://www.ebi.ac.uk/interpro/entry/IPR049573", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR050561", "url": "https://www.ebi.ac.uk/interpro/entry/IPR050561", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "A0A3Q1M6Q3", "url": "https://www.orthodb.org/?gene=A0A3Q1M6Q3", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "F1N3G1", "url": "https://www.orthodb.org/?gene=F1N3G1", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR23339", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR23339", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00782", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00782", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "A0A3Q1M6Q3", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1M6Q3", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A3Q1M6Q3-1", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1M6Q3-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0ABI0NYD3", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NYD3", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0ABI0NYD3-1", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NYD3-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "F1N3G1", "url": "https://www.uniprot.org/uniprotkb/F1N3G1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "F1N3G1-1", "url": "https://www.uniprot.org/uniprotkb/F1N3G1-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MEQAGADISPPALPSWKPSTMQDPPRRLSAVPFLSSFFEGRRHSASDPILRLQQGRRSSAAKVLSSSSLQVMVAMSSVSCAERNPTCPERKRNSGRPTPKYTKVGERLRHVIPGHVACSMACGGKACKYENAARWSEQEQAVKGIYSSWVTDNILAMARPSTEVLEKFCIIEQFRSHGIKSIINLQRPGEHASCGNPLEQESGFTYLPEAFMEAGIYFYNFGWKDYGVASLTTILDMVKVMTFALQEGKVAIHCHAGLGRTGVLIACYLVFATRMTADQAIIFVRAKRPNSIQTRGQLLCVREFTQFLIPLRNIFSCCDPKAHAVTLAQYLIRQRHLLHGYEARLLKHIPKIIHLVCKLLLDLAENRPVVTEVADIPGLSAEIEKTVSEMITRQLDKELLRHDSDASDSFTPTAVVMDFENQDVVLSSEQELDPLWKRRNVECLQPLAHLKRQLSYSDSDLKRAESLLEQGRTPWTVPAQALLCHNPRQQKHISRCYSPQSPQLDLNKETLVRNTFSFWNHTKFGVPEGLKDDGSSIFHRTSIPKEVQRSRTFSSGISDSYNPGEPVTPNFANIPKGPNSSQQKVYHCECESHGGCGPSSVAEDGETCRRPVDCGSSPKAQFLGNETQNSKYLSEVAAHMPLQSELSVEARRILAAKALANLNEIAEKEEVKKKVEMWQKELNSRDGAWERICGEKDPFILCSLMWSWVEQLKEPVITKEDMDMLVDRCADASEALFLLEKGQQQTILCVLHCIVSLQTIPADVEEAVLARAIKAFTKVNFDSENGPIVYNTLKKIFKRTLEEKRKMTKDNPEPGI", "length": 816, "header": "tr|F1N3G1-1|F1N3G1_BOVIN Isoform 1 of Protein tyrosine phosphatase domain-containing protein 1 OS=Bos taurus OX=9913 GN=PTPDC1 PE=3 SV=4 CANONICAL=F1N3G1-1" }, "isoforms": [ { "isoform_ac": "A0A3Q1M6Q3-1", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1M6Q3/entry", "sequence": { "sequence": "MKTTMAAGALPQNEQPYSTLVNNSGYAANMKGNSGRPTPKYTKVGERLRHVIPGHVACSMACGGKACKYENAARWSEQEQAVKGIYSSWVTDNILAMARPSTEVLEKFCIIEQFRSHGIKSIINLQRPGEHASCGNPLEQESGFTYLPEAFMEAGIYFYNFGWKDYGVASLTTILDMVKVMTFALQEGKVAIHCHAGLGRTGVLIACYLVFATRMTADQAIIFVRAKRPNSIQTRGQLLCVREFTQFLIPLRNIFSCCDPKAHAVTLAQYLIRQRHLLHGYEARLLKHIPKIIHLVCKLLLDLAENRPVVTEVADIPGLSAEIEKTVSEMITRQLDKELLRHDSDASDSFTPTAVVMDFENQDVVLSSEQELDPLWKRRNVECLQPLAHLKRQLSYSDSDLKRAESLLEQGRTPWTVPAQALLCHNPRQQKHISRCYSPQSPQLDLNKETLVRNTFSFWNHTKFGVPEGLKDDGSSIFHRTSIPKEVQRSRTFSSGISDSYNPGEPVTPNFANIPKGPNSSQQKVYHCECESHGGCGPSSVAEDGETCRRPVDCGSSPKAQFLGNETQNSKYLSEVAAHMPLQSELSVEARRILAAKALANLNEIAEKEEVKKKVEMWQKELNSRDGAWERICGEKDPFILCSLMWSWVEQLKEPVITKEDMDMLVDRCADASEALFLLEKGQQQTILCVLHCIVSLQTIPADVEEAVLARAIKAFTKGHKEKTAVHKSGRESTPGTKPARP", "length": 742, "header": "tr|A0A3Q1M6Q3-1|F1N3G1_BOVIN Computationally mapped isoform of Protein tyrosine phosphatase domain-containing protein 1 OS=Bos taurus OX=9913 GN=PTPDC1 PE=3 SV=3 CANONICAL=F1N3G1-1" }, "locus": { "chromosome": "8", "start_pos": 85399473, "end_pos": 85326354, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000083815.3", "url": "https://www.ensembl.org/id/ENSBTAT00000083815.3" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000066028.3", "url": "https://www.ensembl.org/id/ENSBTAP00000066028.3" } ] } }, { "isoform_ac": "A0ABI0NYD3-1", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NYD3/entry", "sequence": { "sequence": "MKTTMAAGALPQNEQPYSTLVNNSGYAANMKGNSGRPTPKYTKVGERLRHVIPGHVACSMACGGKACKYENAARWSEQEQAVKGIYSSWVTDNILAMARPSTEVLEKFCIIEQFRSHGIKSIINLQRPGEHASCGNPLEQESGFTYLPEAFMEAGIYFYNFGWKDYGVASLTTILDMVKVMTFALQEGKVAIHCHAGLGRTGVLIACYLVFATRMTADQAIIFVRAKRPNSIQTRGQLLCVREFTQFLIPLRNIFSCCDPKAHAVTLAQYLIRQRHLLHGYEARLLKHIPKIIHLVCKLLLDLAENRPVVTEVADIPGLSAEIEKTVSEMITRQLDKELLRHDSDASDSFTPTAVVMDFENQDVVLSSEQELDPLWKRRNVECLQPLAHLKRQLSYSDSDLKRAESLLEQGRTPWTVPAQALLCHNPRQQKHISRCYSPQSPQLDLNKETLVRNTFSFWNHTKFGVPEGLKDDGSSIFHRTSIPKEVQRSRTFSSGISDSYNPGEPVTPNFANIPKGPNSSQQKVYHCECESHGGCGPSSVAEDGETCRRPVDCGSSPKAQFLGNETQNSKYLSEVAAHMPLQSELSVEARRILAAKALANLNEIAEKEEVKKKVEMWQKELNSRDGAWERICGEKDPFILCSLMWSWVEQLKEPVITKEDMDMLVDRCADASEALFLLEKGQQQTILCVLHCIVSLQTIPADVEEAVLARAIKAFTKVNFDSENGPIVYNTLKKIFKRTLEEKRKMTKDNPEPGI", "length": 756, "header": "tr|A0ABI0NYD3-1|A0ABI0NYD3_BOVIN Computationally mapped isoform of Protein tyrosine phosphatase domain-containing protein 1 OS=Bos taurus OX=9913 GN=PTPDC1 PE=3 SV=1 CANONICAL=F1N3G1-1" }, "locus": { "chromosome": "8", "start_pos": 85382329, "end_pos": 85326354, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000153704.1", "url": "https://www.ensembl.org/id/ENSBTAT00000153704.1" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000107231.1", "url": "https://www.ensembl.org/id/ENSBTAP00000107231.1" } ] } }, { "isoform_ac": "F1N3G1-1", "url": "https://www.uniprot.org/uniprotkb/F1N3G1/entry", "sequence": { "sequence": "MEQAGADISPPALPSWKPSTMQDPPRRLSAVPFLSSFFEGRRHSASDPILRLQQGRRSSAAKVLSSSSLQVMVAMSSVSCAERNPTCPERKRNSGRPTPKYTKVGERLRHVIPGHVACSMACGGKACKYENAARWSEQEQAVKGIYSSWVTDNILAMARPSTEVLEKFCIIEQFRSHGIKSIINLQRPGEHASCGNPLEQESGFTYLPEAFMEAGIYFYNFGWKDYGVASLTTILDMVKVMTFALQEGKVAIHCHAGLGRTGVLIACYLVFATRMTADQAIIFVRAKRPNSIQTRGQLLCVREFTQFLIPLRNIFSCCDPKAHAVTLAQYLIRQRHLLHGYEARLLKHIPKIIHLVCKLLLDLAENRPVVTEVADIPGLSAEIEKTVSEMITRQLDKELLRHDSDASDSFTPTAVVMDFENQDVVLSSEQELDPLWKRRNVECLQPLAHLKRQLSYSDSDLKRAESLLEQGRTPWTVPAQALLCHNPRQQKHISRCYSPQSPQLDLNKETLVRNTFSFWNHTKFGVPEGLKDDGSSIFHRTSIPKEVQRSRTFSSGISDSYNPGEPVTPNFANIPKGPNSSQQKVYHCECESHGGCGPSSVAEDGETCRRPVDCGSSPKAQFLGNETQNSKYLSEVAAHMPLQSELSVEARRILAAKALANLNEIAEKEEVKKKVEMWQKELNSRDGAWERICGEKDPFILCSLMWSWVEQLKEPVITKEDMDMLVDRCADASEALFLLEKGQQQTILCVLHCIVSLQTIPADVEEAVLARAIKAFTKVNFDSENGPIVYNTLKKIFKRTLEEKRKMTKDNPEPGI", "length": 816, "header": "tr|F1N3G1-1|F1N3G1_BOVIN Isoform 1 of Protein tyrosine phosphatase domain-containing protein 1 OS=Bos taurus OX=9913 GN=PTPDC1 PE=3 SV=4 CANONICAL=F1N3G1-1" }, "locus": { "chromosome": "8", "start_pos": 85382329, "end_pos": 85366976, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000007630.8", "url": "https://www.ensembl.org/id/ENSBTAT00000007630.8" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000007630.7", "url": "https://www.ensembl.org/id/ENSBTAP00000007630.7" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [], "orthologs": [], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 1, "go_terms": [ { "name": "cytoplasm", "id": "GO:0005737", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005737", "evidence": [ { "database": "UniProtKB", "id": "F1N3G1", "url": "https://www.uniprot.org/uniprotkb/F1N3G1" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 1, "go_terms": [ { "name": "cilium assembly", "id": "GO:0060271", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0060271", "evidence": [ { "database": "UniProtKB", "id": "F1N3G1", "url": "https://www.uniprot.org/uniprotkb/F1N3G1" } ], "pmid": "" } ] }, { "name": "Molecular Function", "total": 1, "go_terms": [ { "name": "protein tyrosine phosphatase activity", "id": "GO:0004725", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0004725", "evidence": [ { "database": "UniProtKB", "id": "F1N3G1", "url": "https://www.uniprot.org/uniprotkb/F1N3G1" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 520, "end_pos": 522, "annotation": "n_glycosylation_sequon" }, { "start_pos": 579, "end_pos": 581, "annotation": "n_glycosylation_sequon" }, { "start_pos": 625, "end_pos": 627, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [ { "pdb_id": "AF-F1N3G1-F1", "pdb_chain": "global", "start_pos": 1, "end_pos": 816, "overlap": "1.0", "method": "AlphaFold", "type": "alphafold", "resolution": -1.0, "url": "https://data.glygen.org/ln2downloads/pdb/current/AF-F1N3G1-F1.pdb", "url_external": "https://alphafold.ebi.ac.uk/entry/F1N3G1" } ], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "F1N3G1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1N3G1" }, { "id": "PS50056", "database": "PROSITE", "url": "https://prosite.expasy.org/PS50056" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "Tyrosine specific protein phosphatases", "eco_id": "ECO_0000259", "start_pos": 232, "end_pos": 299, "start_aa": "Thr", "end_aa": "Leu", "glycosite_overlap": [] }, { "evidence": [ { "id": "F1N3G1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1N3G1" }, { "id": "PS50054", "database": "PROSITE", "url": "https://prosite.expasy.org/PS50054" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "Tyrosine-protein phosphatase", "eco_id": "ECO_0000259", "start_pos": 146, "end_pos": 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"MQRGASGFRREDLRRKRERERERMSLSDWHLAVKLADQPLAPKSILRLPETELGEYSLGGYSISFLKQLIAGKLQESVPDPELIDLIYCGRKLKDDQTLDFYGIQPGSTVHVLRKSWPEPDQKPEPVDKVAALREFRVLHTALHSSSSYREAVFKMLSNKESLDQIIVATPGLSSDPIALGVLQDKDLFSVFADPNMLDTLVPAHPALVNAIVLVLHSVAGSTPMPGADSSSRGMPSSAYRDMPGGFLFEGLSDDEDDFHPSARSTPSSSTPSSRPASLGYSGAAGPRPITQSELATALALASTPESSSHTPTPGTQGHSSGTSPMSSSVQSGTPITNDLFSQALQHALQASGQPSLQSQWQPQLQQLRDMGIQDDELSLRALQATGGDIQAALELIFAGGAP", "length": 403, "header": "tr|F6RE68-1|F6RE68_BOVIN Isoform 1 of Ubiquitin-like protein 7 OS=Bos taurus OX=9913 GN=UBL7 PE=4 SV=1 CANONICAL=F6RE68-1" }, "isoforms": [ { "isoform_ac": "A0A3Q1M7R8-1", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1M7R8/entry", "sequence": { "sequence": 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"url": "https://www.uniprot.org/uniprotkb/F6RE68" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "F6RE68", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F6RE68" }, { "id": "PS50030", "database": "PROSITE", "url": "https://prosite.expasy.org/PS50030" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "UBA", "eco_id": "ECO_0000259", "start_pos": 356, "end_pos": 400, "start_aa": "Ser", "end_aa": "Gly", "glycosite_overlap": [] }, { "evidence": [ { "id": "F6RE68", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F6RE68" }, { "id": "PS50053", "database": "PROSITE", "url": "https://prosite.expasy.org/PS50053" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "Ubiquitin-like", "eco_id": 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"count": 0 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_pos", "start_aa", "end_pos", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 3 }, { "field": "total_sites", "count": 3 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 3 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "exact_sites", "count": 3 }, { "field": "exact_o_linked_sites", "count": 3 }, { "field": "fuzzy_sites", "count": 0 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_pos", "start_aa", "end_pos", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ], "tool_support": { "graph_view": "yes" } }, { "uniprot_canonical_ac": "F1N6W1-1", "uniprot_ac": "F1N6W1", "uniprot_id": "F1N6W1_BOVIN", "mass": { "chemical_mass": 71371.0, "monoisotopic_mass": 71371.0 }, "refseq": { "ac": "NP_001178983", "name": "tyrosine-protein phosphatase non-receptor type 9", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001178983" }, "gene_names": [ { "name": "PTPN9", "type": "recommended", "evidence": [ { "id": "F1N6W1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1N6W1" } ] }, { "name": "PTPN9", "type": "synonym", "evidence": [ { "id": "NP_001178983", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001178983" } ] } ], "protein_names": [ { "name": "Tyrosine-protein phosphatase non-receptor type 9", "type": "recommended", "evidence": [ { "id": "F1N6W1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1N6W1/entry#names_and_taxonomy" } ] }, { "name": "3.1.3.48", "type": "synonym", "evidence": [ { "id": "F1N6W1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1N6W1/entry#names_and_taxonomy" } ] }, { "name": "tyrosine-protein phosphatase non-receptor type 9", "type": "synonym", "evidence": [ { "id": "NP_001178983", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001178983" } ] } ], "function": [ { "annotation": "Protein-tyrosine phosphatase that could participate in the transfer of hydrophobic ligands or in functions of the Golgi apparatus.", "evidence": [ { "database": "UniProtKB", "id": "A0A3Q1M7S0", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1M7S0#function" }, { "database": "UniProtKB", "id": "ARBA00055430", "url": "https://www.uniprot.org/uniprotkb/ARBA00055430#function" }, { "database": "UniProtKB", "id": "F1N6W1", "url": "https://www.uniprot.org/uniprotkb/F1N6W1#function" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Bos taurus", "taxid": 9913, "evidence": [ { "database": "UniProtKB", "id": "F1N6W1", "url": "https://www.uniprot.org/uniprotkb/F1N6W1" } ], "common_name": "Bovine", "glygen_name": "Bovine", "reference_species": "Bos taurus [9913]" } ], "gene": [ { "name": "PTPN9", "url": "https://www.uniprot.org/uniprotkb/F1N6W1", "locus": { "chromosome": "21", "start_pos": 33375889, "end_pos": 33305768, "strand": "-", "evidence": [ { "database": "Ensembl Gene", "id": "ENSBTAG00000016984", "url": "https://www.ensembl.org/id/ENSBTAG00000016984" } ] } } ], "crossref": [ { "id": "F1N6W1", "url": "https://alphafold.ebi.ac.uk/entry/F1N6W1", "database": "AlphaFoldDB", "categories": [] }, { "id": "ENSBTAG00000016984", "url": "https://bgee.org/?page=gene&gene_id=ENSBTAG00000016984", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "cd00170", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd00170", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "cd14543", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd14543", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "505220", "url": "https://www.ncbi.nlm.nih.gov/gene/505220", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR000242", "url": "https://www.ebi.ac.uk/interpro/entry/IPR000242", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR000387", "url": "https://www.ebi.ac.uk/interpro/entry/IPR000387", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR001251", "url": "https://www.ebi.ac.uk/interpro/entry/IPR001251", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR003595", "url": "https://www.ebi.ac.uk/interpro/entry/IPR003595", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR011074", "url": "https://www.ebi.ac.uk/interpro/entry/IPR011074", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR016130", "url": "https://www.ebi.ac.uk/interpro/entry/IPR016130", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR029021", "url": "https://www.ebi.ac.uk/interpro/entry/IPR029021", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR036273", "url": "https://www.ebi.ac.uk/interpro/entry/IPR036273", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR036865", "url": "https://www.ebi.ac.uk/interpro/entry/IPR036865", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR050348", "url": "https://www.ebi.ac.uk/interpro/entry/IPR050348", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "DLASWNF", "url": "https://omabrowser.org/oma/group/DLASWNF/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "A0A3Q1M7S0", "url": "https://www.orthodb.org/?gene=A0A3Q1M7S0", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "F1N6W1", "url": "https://www.orthodb.org/?gene=F1N6W1", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR19134", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR19134", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR19134:SF285", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR19134:SF285", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00102", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00102", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF00650", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00650", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "NP_001178983", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001178983", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A3Q1M7S0", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1M7S0", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A3Q1M7S0-1", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1M7S0-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "F1N6W1", "url": "https://www.uniprot.org/uniprotkb/F1N6W1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "F1N6W1-1", "url": "https://www.uniprot.org/uniprotkb/F1N6W1-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MRRGHAEAEAHRTGLPALPGDFCPPGGGSGGGMEPATAPQPDMAPELTPEEEQATKQFLEEINKWTVQYNVSPLSWNVAVKFLMARKFDVLRAIELFHSYRETRRKEGIVKLKPHEEPLRSEILSGKFTILNVRDPTGASIALFTARLHHPHKSVQHVVLQALFYLLDRAVDSFETQRNGLVFIYDMCGSNYTNFELDLGKKVLNLLKGAFPARLKKVLIVGAPIWFRVPYSIISLLLKDKVRERIQILKTSEVTQHLPRECLPENLGGYVKIDLATWNFQFLSQMNGHPDPFDEIILFSLPPALDWDSVHVPDPQAMTIQELMDYVSTRQKRGIYEEYEDIRRENPVGTFHCSMSPGNLEKNRYGDVPCLDQTRVKLTKRSGHTQTDYINASFMDGYKQKNAYIGTQGPLENTYRDFWLMVWEQKVLVIVMTTRFEEGGRRKCGQYWPLEKDSRIRFGFLTVTNLGVENMTHYKKTTLEIHNIEERQKRQVTHFQFLSWPDYGVPSSAASLIDFLRAVRNQQRLAVSSMGARTKGQCPEPPIVVHCSAGIGRTGTFCSLDICLAQLEELGTLNVFQTVSRMRTQRAFSIQTPEQYYFCYKAILEFAEREGMVPPSHNLLAMEGQ", "length": 625, "header": "tr|F1N6W1-1|F1N6W1_BOVIN Isoform 1 of Tyrosine-protein phosphatase non-receptor type 9 OS=Bos taurus OX=9913 GN=PTPN9 PE=3 SV=4 CANONICAL=F1N6W1-1" }, "isoforms": [ { "isoform_ac": "A0A3Q1M7S0-1", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1M7S0/entry", "sequence": { "sequence": "MQATKQFLEEINKWTVQYNVSPLSWNVAVKFLMARKFDVLRAIELFHSYRETRRKEGIVKLKPHEEPLRSEILSGKFTILNVRDPTGASIALFTARLHHPHKSVQHVVLQALFYLLDRAVDSFETQRNGLVFIYDMCGSNYTNFELDLGKKVLNLLKGAFPARLKKVLIVGAPIWFRVPYSIISLLLKDKVRERIQILKTSEVTQHLPRECLPENLGGYVKIDLATWNFQFLSQMNGHPDPFDEIILFSLPPALDWDSVHVPDPQAMTIQELMDYVSTRQKRGIYEEYEDIRRENPVGTFHCSMSPGNLEKNRYGDVPCLDQTRVKLTKRSGHTQTDYINASFMDGYKQKNAYIGTQGPLENTYRDFWLMVWEQKVLVIVMTTRFEEGGRRKCGQYWPLEKDSRIRFGFLTVTNLGVENMTHYKKTTLEIHNIEERQKRQVTHFQFLSWPDYGVPSSAASLIDFLRAVRNQQRLAVSSMGARTKGQCPEPPIVVHCSAGIGRTGTFCSLDICLAQLEELGTLNVFQTVSRMRTQRAFSIQTPEQYYFCYKAILEFAEREGMVPPSHNLLAMEGQ", "length": 574, "header": "tr|A0A3Q1M7S0-1|F1N6W1_BOVIN Computationally mapped isoform of Tyrosine-protein phosphatase non-receptor type 9 OS=Bos taurus OX=9913 GN=PTPN9 PE=3 SV=2 CANONICAL=F1N6W1-1" }, "locus": { "chromosome": "21", "start_pos": 33374209, "end_pos": 33314996, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000067352.2", "url": "https://www.ensembl.org/id/ENSBTAT00000067352.2" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000066119.2", "url": "https://www.ensembl.org/id/ENSBTAP00000066119.2" } ] } }, { "isoform_ac": "F1N6W1-1", "url": "https://www.uniprot.org/uniprotkb/F1N6W1/entry", "sequence": { "sequence": "MRRGHAEAEAHRTGLPALPGDFCPPGGGSGGGMEPATAPQPDMAPELTPEEEQATKQFLEEINKWTVQYNVSPLSWNVAVKFLMARKFDVLRAIELFHSYRETRRKEGIVKLKPHEEPLRSEILSGKFTILNVRDPTGASIALFTARLHHPHKSVQHVVLQALFYLLDRAVDSFETQRNGLVFIYDMCGSNYTNFELDLGKKVLNLLKGAFPARLKKVLIVGAPIWFRVPYSIISLLLKDKVRERIQILKTSEVTQHLPRECLPENLGGYVKIDLATWNFQFLSQMNGHPDPFDEIILFSLPPALDWDSVHVPDPQAMTIQELMDYVSTRQKRGIYEEYEDIRRENPVGTFHCSMSPGNLEKNRYGDVPCLDQTRVKLTKRSGHTQTDYINASFMDGYKQKNAYIGTQGPLENTYRDFWLMVWEQKVLVIVMTTRFEEGGRRKCGQYWPLEKDSRIRFGFLTVTNLGVENMTHYKKTTLEIHNIEERQKRQVTHFQFLSWPDYGVPSSAASLIDFLRAVRNQQRLAVSSMGARTKGQCPEPPIVVHCSAGIGRTGTFCSLDICLAQLEELGTLNVFQTVSRMRTQRAFSIQTPEQYYFCYKAILEFAEREGMVPPSHNLLAMEGQ", "length": 625, "header": "tr|F1N6W1-1|F1N6W1_BOVIN Isoform 1 of Tyrosine-protein phosphatase non-receptor type 9 OS=Bos taurus OX=9913 GN=PTPN9 PE=3 SV=4 CANONICAL=F1N6W1-1" }, "locus": { "chromosome": "21", "start_pos": 33374209, "end_pos": 33305872, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000022588.6", "url": "https://www.ensembl.org/id/ENSBTAT00000022588.6" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000022588.6", "url": "https://www.ensembl.org/id/ENSBTAP00000022588.6" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [ "enzyme" ], "publication": [], "pathway": [], "orthologs": [ { "uniprot_canonical_ac": "A0A8V0ZCL5-1", "protein_name": "Tyrosine-protein phosphatase non-receptor type 9", "gene_name": "PTPN9", "tax_id": 9031, "organism": "Gallus gallus", "sequence": { "sequence": "MAESTLMPLFPFSKQPPGRRKGRAKGSATKQFLEEINKWTGQYNVSPLSWNVAVKFLMARKFDVLRAIELFHSYRETRLKEGIVKLKPHEEPLRSELLSGKFTILSVRDPSGASIALFTAKLHHPSRSVQHVVLQALFYLLDRAVESFETQRNGLVFIYDMAGSQYTNFELDLSKKILNLLKGAFPARLKKVFIVGAPMWFRVPYSIISLLLKEKLRERVQMVKMSELKEHLPRECLPETLGGCLKLDPLSWNCRFLPQQNGHPDPLDELILVPLVTPRDNGSLHVPGPKALTPQELLEHISRKQKRGIYEEYEDIRRRSPAGTFVCSLAPYNQEKNRYGDVPCLDQTRVKLAKPYSRPELTDYINASFMDGYKQRNAYIGTQGPLENTYGDFWRMVWEQNVLVIVMTTRLEEGGRRKCGQYWPLEKDFQMRFGALTITNLGVENLSHYKKTILEIHSAEGRERRLLSHFQYLSWPDYGVPSSAATLIDFLGAVKQQQRVAVSALGPRFKGHPGGPPIVVHCSAGIGRTGTLCALDICLSQLQDVGTLDIQQTVQRMRTQRAFSIQTPEQYYFCYSAVLEHAQRRGLLPAGQKGSAGH", "length": 598 }, "evidence": [ { "id": "F1N6W1", "url": "https://omabrowser.org/oma/group/F1N6W1/", "database": "OMA" } ], "glygen_name": "Chicken", "common_name": "Chicken" }, { "uniprot_canonical_ac": "E7F716-1", "protein_name": "Tyrosine-protein phosphatase non-receptor type 9", "gene_name": "ptpn9a", "tax_id": 7955, "organism": "Danio rerio", "sequence": { "sequence": "MMADRLSAEEEQATKQFLEEINKWTSQHGVSPLSWDVAVKFLMARKFDVLRAIELFHSYRETRLREGIVKLQPHKEPLRSELLSGKFTVLGVRDPSGASIALYTAKLHHPSKTGNHVVLQALFYLLDRAVESFETQRNGLVFIYDMAGSNYTNFELDLSKKILNLLKGAFPARLKKVLIVGAPVWFRVPYNLLSLLLKEKLRERVQMVKMADLRQHLPRDCLPEHLGGCLPLDVHNWNLQLLSEQNGRVDPVDELVGIPLENTSIHTPGAEAMSLAELMAHLNRAQRSGIYLEYEELRREQPPGTFTCALAAHNQERNRYGDVLCLDQTRVRLKARRNERSDYINASFMDGYKQKNAYIGTQGPLEKTYGDFWRMVWEQNVLVIVMTTRTDEGGRRKCGQYWPQEEGGQEVYGYIAVVNHRVDNHAHYNQTTLELHNTETFEQRQVTHFQFLSWPDYGVPSSAVSLIDFLGAVKHQQQWAVQAFGTQWRGHPLGPPMVVHCSAGIGRTGTFCALDICLSQLQDVGTLNICQTVRRMRSQRAFSIQTPEQYYFCHAAILEHAQRQGLLSANQ", "length": 571 }, "evidence": [ { "id": "F1N6W1", "url": "https://omabrowser.org/oma/group/F1N6W1/", "database": "OMA" } ], "glygen_name": "Zebrafish", "common_name": "Zebrafish" }, { "uniprot_canonical_ac": "F1SJ71-1", "protein_name": "Tyrosine-protein phosphatase non-receptor type 9", "gene_name": "PTPN9", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MEPATAPQPDMAPELTPEEEQATKQFLEEINKWTVQYNVSPLSWNVAVKFLMARKFDVLRAIELFHSYRETRRKEGIVKLKPHEEPLRSEILSGKFTILNVRDPTGASIALFTARLHHPHKSVQHVVLQALFYLLDRAVDSFETQRNGLVFIYDMCGSNYANFELDLGKKVLNLLKGAFPARLKKVLIVGAPIWFRVPYSIISLLLKDKVRERIQILKTSEVTQHLPRECLPENLGGYVKIDLATWNFQFLSQMNGHPDPFDEIILFSLPPALDWDSVHVPDPHAMTIQELMDYVSTRQKRGIYEEYEDIRRENPVGTFHCSMSPGNLEKNRYGDVPCLDQTRVKLTKRSGHTQTDYINASFMDGYKQKNAYIGTQGPLENTYRDFWLMVWEQKVLVIVMTTRFEEGGRRKCGQYWPLEKDSRIRFGFLTVTNLGVENMNHYKKTTLEIHNTEERQKRQVTHFQFLSWPDYGVPSSAASLIDFLRAVRSQQRLAVSSMGARSKGQCPEPPIVVHCSAGIGRTGTFCSLDICLAQLEELGTLNVFQTVSRMRTQRAFSIQTPEQYYFCYKAILEFAEREGMVPSSHNLLAMEGQ", "length": 593 }, "evidence": [ { "id": "F1N6W1", "url": "https://omabrowser.org/oma/group/F1N6W1/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "O35239-1", "protein_name": "Tyrosine-protein phosphatase non-receptor type 9", "gene_name": "Ptpn9", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MEPATAPRPDMAPELTPEEEQATKQFLEEINKWTVQYNVSPLSWNVAVKFLMARKFDVLRAVELFHCYRETRRKEGIVKLKPHEEPLRSEILSGKFTILNVRDPTGASIALFTARLHHPHKSAQHVVLQALFYLLDRAVDSFETQRNGLVFIYDMCGSNYANFELDLGKKVLNLLKGAFPARLKKVLIVGAPIWFRVPYSIISLLLKDKVRERIQILKTSEVTQHLPRECLPENLGGYVKIDLATWNFQFLPQVNGHPDPFDEIILSSLPPALDWDSVHVPGPHAMTIQELVDYVNTRQKRGIYEEYEDIRRENPVGTFHCSMSPGNLEKNRYGDVPCLDQTRVKLTKRSGHTQTDYINASFMDGYKQKNAYIGTQGPLENTYRDFWLMVWEQKVLVIVMTTRFEEGGRRKCGQYWPLEKDSRIRFGFLTVTNLGVENMNHYKKTTLEIHNTEERQKRQVTHFQFLSWPDYGVPSSAASLIDFLRVVRNQQSMAVGNLGARSKGQCPEPPIVVHCSAGIGRTGTFCSLDICLAQLEELGTLNVFQTVSRMRTQRAFSIQTPEQYYFCYKAILEFAEREGMVPSGHSLLAMDGQ", "length": 593 }, "evidence": [ { "id": "F1N6W1", "url": "https://omabrowser.org/oma/group/F1N6W1/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "P43378-1", "protein_name": "Tyrosine-protein phosphatase non-receptor type 9", "gene_name": "PTPN9", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MEPATAPRPDMAPELTPEEEQATKQFLEEINKWTVQYNVSPLSWNVAVKFLMARKFDVLRAIELFHSYRETRRKEGIVKLKPHEEPLRSEILSGKFTILNVRDPTGASIALFTARLHHPHKSVQHVVLQALFYLLDRAVDSFETQRNGLVFIYDMCGSNYANFELDLGKKVLNLLKGAFPARLKKVLIVGAPIWFRVPYSIISLLLKDKVRERIQILKTSEVTQHLPRECLPENLGGYVKIDLATWNFQFLPQVNGHPDPFDEIILFSLPPALDWDSVHVPGPHAMTIQELVDYVNARQKQGIYEEYEDIRRENPVGTFHCSMSPGNLEKNRYGDVPCLDQTRVKLTKRSGHTQTDYINASFMDGYKQKNAYIGTQGPLENTYRDFWLMVWEQKVLVIVMTTRFEEGGRRKCGQYWPLEKDSRIRFGFLTVTNLGVENMNHYKKTTLEIHNTEERQKRQVTHFQFLSWPDYGVPSSAASLIDFLRVVRNQQSLAVSNMGARSKGQCPEPPIVVHCSAGIGRTGTFCSLDICLAQLEELGTLNVFQTVSRMRTQRAFSIQTPEQYYFCYKAILEFAEKEGMVSSGQNLLAVESQ", "length": 593 }, "evidence": [ { "id": "F1N6W1", "url": "https://omabrowser.org/oma/group/F1N6W1/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "Q641Z2-1", "protein_name": "Tyrosine-protein phosphatase non-receptor type 9", "gene_name": "Ptpn9", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MEPATAPRPDMAPELTPEEEQATKQFLEEINKWTVQYNVSPLSWNVAVKFLMARKFDVLRAVELFHCYRETRRKEGIVKLKPHEEPLRSEILSGKFTILNVRDPTGASIALFTARLHHPHKSVQHVVLQALFYLLDRAVDSFETQRNGLVFIYDMCGSNYANFELDLGKKVLNLLKGAFPARLKKVLIVGAPIWFRVPYSIISLLLKDKVRERIQILKTSEVTQHLPRECLPENLGGYIKIDLATWNFQFLPQVNGHPDPFDEIILFSLPPALDWDSVHVPGPHAMTIQELVDYVNTRQKQGIYEEYEDIRRENPVGTFHCSMSPGNLEKNRYGDVPCLDQTRVKLTKRSGHTQTDYINASFMDGYKQKNAYIGTQGPLENTYRDFWLMVWEQKVLVIVMTTRFEEGGRRKCGQYWPLEKDSRIQFGFLTVTNLGVENMNHYKKTTLEIHNTEERQKRQVTHFQFLSWPDYGVPSSAASLIDFLRVVRSQQSMAVGSLGARSKGQCPEPPIVVHCSAGIGRTGTFCSLDICLAQLEELGTLNVFQTVSRMRTQRAFSIQTPEQYYFCYKAILEFAEREGMVPSGHSLLAMDGQ", "length": 593 }, "evidence": [ { "id": "F1N6W1", "url": "https://omabrowser.org/oma/group/F1N6W1/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" } ], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 2, "go_terms": [ { "name": "cytoplasm", "id": "GO:0005737", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005737", "evidence": [ { "database": "UniProtKB", "id": "F1N6W1", "url": "https://www.uniprot.org/uniprotkb/F1N6W1" } ], "pmid": "" }, { "name": "neuron projection terminus", "id": "GO:0044306", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0044306", "evidence": [ { "database": "UniProtKB", "id": "F1N6W1", "url": "https://www.uniprot.org/uniprotkb/F1N6W1" } ], "pmid": "" } ] }, { "name": "Molecular Function", "total": 1, "go_terms": [ { "name": "protein tyrosine phosphatase activity", "id": "GO:0004725", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0004725", "evidence": [ { "database": "UniProtKB", "id": "F1N6W1", "url": "https://www.uniprot.org/uniprotkb/F1N6W1" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 1, "go_terms": [ { "name": "signal transduction", "id": "GO:0007165", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007165", "evidence": [ { "database": "UniProtKB", "id": "F1N6W1", "url": "https://www.uniprot.org/uniprotkb/F1N6W1" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 191, "end_pos": 193, "annotation": "n_glycosylation_sequon" }, { "start_pos": 391, "end_pos": 393, "annotation": "n_glycosylation_sequon" }, { "start_pos": 470, "end_pos": 472, "annotation": "n_glycosylation_sequon" }, { "start_pos": 70, "end_pos": 72, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [ { "pdb_id": "AF-F1N6W1-F1", "pdb_chain": "global", "start_pos": 1, "end_pos": 625, "overlap": "1.0", "method": "AlphaFold", "type": "alphafold", "resolution": -1.0, "url": "https://data.glygen.org/ln2downloads/pdb/current/AF-F1N6W1-F1.pdb", "url_external": "https://alphafold.ebi.ac.uk/entry/F1N6W1" } ], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "F1N6W1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1N6W1" }, { "id": "PS50191", "database": "PROSITE", "url": "https://prosite.expasy.org/PS50191" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "CRAL-TRIO", "eco_id": "ECO_0000259", "start_pos": 116, "end_pos": 275, "start_aa": "Glu", "end_aa": "Leu", "glycosite_overlap": [] }, { "evidence": [ { "id": "F1N6W1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1N6W1" }, { "id": "PS50056", "database": "PROSITE", "url": "https://prosite.expasy.org/PS50056" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "Tyrosine specific protein phosphatases", "eco_id": "ECO_0000259", "start_pos": 513, "end_pos": 597, "start_aa": "Ile", "end_aa": "Tyr", "glycosite_overlap": [] }, { "evidence": [ { "id": "F1N6W1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1N6W1" }, { "id": "PS50055", "database": "PROSITE", "url": "https://prosite.expasy.org/PS50055" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "Tyrosine-protein phosphatase", "eco_id": "ECO_0000259", "start_pos": 335, "end_pos": 606, "start_aa": "Ile", "end_aa": "Phe", "glycosite_overlap": [] } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [ { "ec_number": "3.1.3.48", "ec_name": "O-phospho-L-tyrosyl-[protein] + H2O = L-tyrosyl-[protein] + phosphate.", "evidence": [ { "id": "3.1.3.48", "database": "Rhea", "url": "https://www.rhea-db.org/rhea/?query=ec:3.1.3.48" }, { "id": "3.1.3.48", "database": "BRENDA Enzymes", "url": "https://www.brenda-enzymes.org/enzyme.php?ecno=3.1.3.48" } ] } ], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" }, { "name": "homologset.oma", "label": "OMA Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 191, "end_pos": 193 }, { "start_pos": 391, "end_pos": 393 }, { "start_pos": 470, "end_pos": 472 }, { "start_pos": 70, "end_pos": 72 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ], "tool_support": { "graph_view": "yes" } }, { "uniprot_canonical_ac": "F6QX85-1", "uniprot_ac": "F6QX85", "uniprot_id": "F6QX85_BOVIN", "mass": { "chemical_mass": 65123.0, "monoisotopic_mass": 65123.0 }, "refseq": {}, "gene_names": [ { "name": "CCDC9", "type": "recommended", "evidence": [ { "id": "F6QX85", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F6QX85" } ] } ], "protein_names": [ { "name": "Coiled-coil domain containing 9", "type": "synonym", "evidence": [ { "id": "F6QX85", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F6QX85/entry#names_and_taxonomy" } ] } ], "function": [], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Bos taurus", "taxid": 9913, "evidence": [ { "database": "UniProtKB", "id": "F6QX85", "url": "https://www.uniprot.org/uniprotkb/F6QX85" } ], "common_name": "Bovine", "glygen_name": "Bovine", "reference_species": "Bos taurus [9913]" } ], "gene": [ { "name": "CCDC9", "url": "https://www.uniprot.org/uniprotkb/F6QX85", "locus": { "chromosome": "18", "start_pos": 54282773, "end_pos": 54269220, "strand": "-", "evidence": [ { "database": "Ensembl Gene", "id": "ENSBTAG00000014117", "url": "https://www.ensembl.org/id/ENSBTAG00000014117" } ] } } ], "crossref": [ { "id": "F6QX85", "url": "https://alphafold.ebi.ac.uk/entry/F6QX85", "database": "AlphaFoldDB", "categories": [] }, { "id": "ENSBTAG00000014117", "url": "https://bgee.org/?page=gene&gene_id=ENSBTAG00000014117", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "IPR029336", "url": "https://www.ebi.ac.uk/interpro/entry/IPR029336", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "DDRWEPK", "url": "https://omabrowser.org/oma/group/DDRWEPK/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "A0A3Q1MAI0", "url": "https://www.orthodb.org/?gene=A0A3Q1MAI0", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "F6QX85", "url": "https://www.orthodb.org/?gene=F6QX85", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR15635", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR15635", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR15635:SF11", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR15635:SF11", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF15266", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF15266", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "A0A3Q1MAI0", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1MAI0", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A3Q1MAI0-1", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1MAI0-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "F6QX85", "url": "https://www.uniprot.org/uniprotkb/F6QX85", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "F6QX85-1", "url": "https://www.uniprot.org/uniprotkb/F6QX85-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MSAALDLKSKEEKDAELDKRIEALRRKNEALIRRYQEIEEDRKKAELEGVAVTGPRKSRSVEKENVAVEKNLGPSRRSPGTPRPPGVSKGGRIPPQHGGRAGMGRTSRSWEDSPGEQPRGGAGGRSRRGRGRGSPHLSGGGDASTADRKSKEWEERRKQNIEKMNEEMEKIAEYERNQREGVLEPNPVRNFLDDPRRRSGPLEEPERDRREGSRRHGRNWGGSDFERVRYGLEQERQGRRAGLGGAGDMTLSMTGRERSEYLRWKQEREKIDQERLQRHRKPTGQWRREWDAEKTDGMFKDGPAVALEPSHRYDDQAWARPPKPPTFREFLSQHKTEVSRRKKKSSRPQPKAAPRAYSDHDDRWEMKEAMSTAPEPPQPALPKEAPTQLPETPAPAHRPPEDEGEEGEDEGEDEEWEDVSEDEEEEEEIEEEEEADDEEEEPAGDHQPQEAEPSGSPAREHGDKETARPEEPLPLPQAPATPSSPFSPPGGHQPVSDWGEEMELNSPRTAHPADAVSPGGDQPAPASLESGPSAPGAQKAEEEGSEAAPEADPEGQETAEIADFQRVRFCKVVAAASPPGAAR", "length": 583, "header": "tr|F6QX85-1|F6QX85_BOVIN Isoform 1 of Coiled-coil domain containing 9 OS=Bos taurus OX=9913 GN=CCDC9 PE=4 SV=1 CANONICAL=F6QX85-1" }, "isoforms": [ { "isoform_ac": "A0A3Q1MAI0-1", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1MAI0/entry", "sequence": { "sequence": "MSAALDLKSKEEKDAELDKRIEALRRKNEALIRRYQEIEEDRKKAELEGVAVTGPRKSRSVEKENVAVEKNLGPSRRSPGTPRPPGVSKGGRIPPQHGGRAGMGRTSRSWEDSPGEQPRGGAGGRSRRGRGRGSPHLSGGGDASTADRKSKEWEERRKQNIEKMNEEMEKIAEYERNQREGVLEPNPVRNFLDDPRRRSGPLEEPERDRREGSRRHGRNWGGSDFERVRYGLEQERQGRRAGLGGAGDMTLSMTGRERSEYLRWKQEREKIDQERLQRHRKPTGQWRREWDAEKTDGMFKDGPAVALEPSHRYDDQAWARPPKPPTFREFLSQHKTEVSRRKKKSSRPQPKAAPRAYSDHDDRWEMKEAMSTAPEPPQPALPKEAPTQLPETPAPAHRPPEDEGEEGEDEGEDEEWEDVSEDEEEEEEIEEEEEADDEEEEPAGDHQPQEAEPSGSPAREHGDKETARPEEPLPLPQAPATPSSPFSPPGGHQPVSDWGEEMELNSPRTAHPADAVSPEADPEGQETAEIADFQRASPNS", "length": 540, "header": "tr|A0A3Q1MAI0-1|F6QX85_BOVIN Computationally mapped isoform of Coiled-coil domain containing 9 OS=Bos taurus OX=9913 GN=CCDC9 PE=4 SV=2 CANONICAL=F6QX85-1" }, "locus": { "chromosome": "18", "start_pos": 54281769, "end_pos": 54271015, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000078314.2", "url": "https://www.ensembl.org/id/ENSBTAT00000078314.2" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000065577.2", "url": "https://www.ensembl.org/id/ENSBTAP00000065577.2" } ] } }, { "isoform_ac": "F6QX85-1", "url": "https://www.uniprot.org/uniprotkb/F6QX85/entry", "sequence": { "sequence": "MSAALDLKSKEEKDAELDKRIEALRRKNEALIRRYQEIEEDRKKAELEGVAVTGPRKSRSVEKENVAVEKNLGPSRRSPGTPRPPGVSKGGRIPPQHGGRAGMGRTSRSWEDSPGEQPRGGAGGRSRRGRGRGSPHLSGGGDASTADRKSKEWEERRKQNIEKMNEEMEKIAEYERNQREGVLEPNPVRNFLDDPRRRSGPLEEPERDRREGSRRHGRNWGGSDFERVRYGLEQERQGRRAGLGGAGDMTLSMTGRERSEYLRWKQEREKIDQERLQRHRKPTGQWRREWDAEKTDGMFKDGPAVALEPSHRYDDQAWARPPKPPTFREFLSQHKTEVSRRKKKSSRPQPKAAPRAYSDHDDRWEMKEAMSTAPEPPQPALPKEAPTQLPETPAPAHRPPEDEGEEGEDEGEDEEWEDVSEDEEEEEEIEEEEEADDEEEEPAGDHQPQEAEPSGSPAREHGDKETARPEEPLPLPQAPATPSSPFSPPGGHQPVSDWGEEMELNSPRTAHPADAVSPGGDQPAPASLESGPSAPGAQKAEEEGSEAAPEADPEGQETAEIADFQRVRFCKVVAAASPPGAAR", "length": 583, "header": "tr|F6QX85-1|F6QX85_BOVIN Isoform 1 of Coiled-coil domain containing 9 OS=Bos taurus OX=9913 GN=CCDC9 PE=4 SV=1 CANONICAL=F6QX85-1" }, "locus": { "chromosome": "18", "start_pos": 54281240, "end_pos": 54271015, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000018765.7", "url": "https://www.ensembl.org/id/ENSBTAT00000018765.7" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000018765.6", "url": "https://www.ensembl.org/id/ENSBTAP00000018765.6" } ] } } ], "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "other", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 481, "start_aa": "Thr", "end_pos": 481, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr481", "evidence": [ { "id": "", "database": "GlyGen", "url": "https://data.glygen.org/" } ], "filter_code": "000000000000000010000.00000000001000.0.01000" } ], "phosphorylation": [], "glycation": [], "keywords": [ "glycoprotein", "glycoprotein_predicted" ], "publication": [], "pathway": [], "orthologs": [ { "uniprot_canonical_ac": "A0A287ABU0-1", "protein_name": "Coiled-coil domain containing 9", "gene_name": "CCDC9", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MSATLDLKSKEEKDAELDKRIEALRRKNEALIRRYQEIEEDRKKAELEGVAVTAPRKGRSVEKENVAVGTEKTLGPSRRSPGTPRPPGASKGGRIPPQQGGRAGMGRASRSWEDSPGEQLRGGAGGRGRRGRGRGSPRLAGAGDASTADRKSKEWEERRRQNIEKMNEEMEKIAEYERNQREGVLEPNPVRNFLDDPRRRSGPLEEPERDRREGSRRHGRNWGGSDFERVRCGLEQERQGRRAGLGGAGDMTLSMTGRERSEYLRWKQEREKIDQERLQRHRKPTGQWRREWDAEKTDGMFKDGPAAAPELSHRYDDQAWARPPKPPTFREFLSQHKAEVSRRRRKSSRPQAKAVPGAYSDHDDRWESKEAVSPAPEPPQPVRPEEPPTQLPETPTPAHQPPEDEGEEYEGEAGDGEDEEWEDVSEEEEIEEEEAEEEEEEEPAPTGDHQPHKAEPSGSPAREHADQEPARPEEPLPPPQAPATPSSPFSPSGGHQPVSDWGEEMELNSPRTPHPADALSPGGDPPASASLESGPSLPGTQKAEEEGSEAAPEAGREGQETAISDFQRASPNS", "length": 573 }, "evidence": [ { "id": "F6QX85", "url": "https://omabrowser.org/oma/group/F6QX85/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "F1QCF9-1", "protein_name": "Coiled-coil domain-containing protein 9 isoform X1", "gene_name": "ccdc9", "tax_id": 7955, "organism": "Danio rerio", "sequence": { "sequence": "MSAVVDLKTKEEKDAELDKRIEALRKKNEALVKRYQEIQEDKKKAEQEGIAVTTARKPRPHEHESERRKTEKENFTVTVDLSKPAGEKRFTNDRKPAGPRGDPGPEEEEPGRPHGESPPNRTGSGRLSRGGQRRERREPRPNKGEPRPDRQPQDGEVGESPAHTERSSRGGRRGGRGGGGGGGGMQAGPGSDRKSKEWEEKRRQNIEKMNEEMEKIAEYERGQRADGEKIPMRNFLDDPRRSGPIPDTDRKEGSRRHVRNWGGVDFDNVKTGPEVEKEWTNRRPGGKGSVDMTLSMTGRERAEYLRWKKEREQIDEERLARHRNATGQWRREWDAQKTDTMFKEESAVAGESMQEQSNRRAARGRNTHAQQRGAPSEDNKKPPKTPTFGDFLGQGKPRQAGGRGRGKGKSYSMHDNRWEGENEEEKGRKEEQEKEKDEEKDKEKENENEDSTLKAPLSEKKTEEEEEDEWEDASDGEEEDVEEDEKADHEEDTKDAKSKEKSISSAASSTPSPKGQRTPRPKVHIPSPKEMLSTPEAAKPPSPFSPLDGHQPVSDWGEEMEMLSPKSSLGESPLRPSSTESSPAQAKSNPAEKDATDTHSHSEESEITPTVVDSTSCETKKESLRAKSPDTTTSSSQEPIVSPTSDSTSQSKEIDVPNVELDQSQCETSPEEETSVDSSEQPSTG", "length": 685 }, "evidence": [ { "id": "F6QX85", "url": "https://omabrowser.org/oma/group/F6QX85/", "database": "OMA" } ], "glygen_name": "Zebrafish", "common_name": "Zebrafish" }, { "uniprot_canonical_ac": "M0RA86-1", "protein_name": "Coiled-coil domain containing 9", "gene_name": "Ccdc9", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MRPSSGATRCPSPALETPSPLLPAEIEEDRKKAELEGVAVTAPRKSRSMEKENMAVEEKNLGPSRRTPGTPRPPGASRGGRTHPQQGGRAGVGRASRGWEDGAGEQLRGGTGGRGRRGRGRGSPHLLGAGDNSTSDRKSKEWEERRRQNIEKMNEEMERIAEYERNQREGVLEPNPVRNFLDDPRRRGGPLEESERDRREGSRRHGRNWGGSDFERVRSGLEQERQGRRAGLGSGGDMTMSMTGRERSEYLRWKQEREKIDQERLQRHRKPTGQWRREWDAEKTDGMFKDGPAPTHEPSHRYDDQAWARPPKPPTFGEFLSQHKAEVNSRRRRKNSRPQAKVAPRAYSDHDNRWETKEEAVSPAPKSSQSMSLEETPTQPPETPAPAHRPPEEDGEEDVGEEEEGEEEGEDDDEDEEWEDVSEDVTEEEEEEEEEFEEEEESPKEQEAAAVPDHQPEAEPAGKPTCEQVDPVPAGPQELLSPVPVEPPSPFSPSEDHQPVSDWGGDQPALASLESRPTLAGTLKSEEEGSEASPGGMHEAGGEVVGPEGQETAEITDFQRSRNPEDAGGRGGSAGLPGSQAGCSPPCSPPWILRL", "length": 595 }, "evidence": [ { "id": "F6QX85", "url": "https://omabrowser.org/oma/group/F6QX85/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "Q8VC31-1", "protein_name": "Coiled-coil domain-containing protein 9", "gene_name": "Ccdc9", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MATTLDLKSKEEKDAELDKRIEALRRKNEALIRRYQEIEEDRKKAELEGVAVTAPRKSRSMEKENMAVEEKSLGPSRRTPGTPRPPGASRGGRTHPQQGGRAGVGRASQGWEDGAGEQLRGGPGGRGRRGRGRGSPHLLGAGDNSTSDRKSKEWEERRRQNIEKMNEEMEKIAEYERNQREGVLEPNPVRNFLDDPRRRGGPLEESERDRREGSRRHGRNWGGSDFERVRSGLEQERQGRRAGLGSGGDMTMSMTGRERSEYLRWKQEREKIDQERLQRHRKPTGQWRREWDAEKTDGMFKDGPAPTHELSHRYDDQAWARPPKPPTFGEFLSQHKAEVSSRRRRKNSRPQAKVAPRAYSDHDNRWETREEAVSSAPESSQSISLEETPTQASETPAPAHRPPEEDGEEDVGEEEEGEEEGEDEEDEEWEDVSEDVTEEEEEEEEEFEEDEEGPKDQEAATVPDHQPEAEPAGKPTCEQVDPVPAGSQELLSPVPVEPPIPFSPSEDHQPVSDWGEEMELNSPGTAHLPGTHSSGEAWPFANA", "length": 543 }, "evidence": [ { "id": "F6QX85", "url": "https://omabrowser.org/oma/group/F6QX85/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q9Y3X0-1", "protein_name": "Coiled-coil domain-containing protein 9", "gene_name": "CCDC9", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MAATLDLKSKEEKDAELDKRIEALRRKNEALIRRYQEIEEDRKKAELEGVAVTAPRKGRSVEKENVAVESEKNLGPSRRSPGTPRPPGASKGGRTPPQQGGRAGMGRASRSWEGSPGEQPRGGGAGGRGRRGRGRGSPHLSGAGDTSISDRKSKEWEERRRQNIEKMNEEMEKIAEYERNQREGVLEPNPVRNFLDDPRRRSGPLEESERDRREESRRHGRNWGGPDFERVRCGLEHERQGRRAGLGSAGDMTLSMTGRERSEYLRWKQEREKIDQERLQRHRKPTGQWRREWDAEKTDGMFKDGPVPAHEPSHRYDDQAWARPPKPPTFGEFLSQHKAEASSRRRRKSSRPQAKAAPRAYSDHDDRWETKEGAASPAPETPQPTSPETSPKETPMQPPEIPAPAHRPPEDEGEENEGEEDEEWEDISEDEEEEEIEVEEGDEEEPAQDHQAPEAAPTGIPCSEQAHGVPFSPEEPLLEPQAPGTPSSPFSPPSGHQPVSDWGEEVELNSPRTTHLAGALSPGEAWPFESV", "length": 531 }, "evidence": [ { "id": "F6QX85", "url": "https://omabrowser.org/oma/group/F6QX85/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" } ], "go_annotation": { "categories": [ { "name": "Molecular Function", "total": 1, "go_terms": [ { "name": "RNA binding", "id": "GO:0003723", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003723", "evidence": [ { "database": "UniProtKB", "id": "F6QX85", "url": "https://www.uniprot.org/uniprotkb/F6QX85" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 1, "go_terms": [ { "name": "exon-exon junction complex", "id": "GO:0035145", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0035145", "evidence": [ { "database": "UniProtKB", "id": "F6QX85", "url": "https://www.uniprot.org/uniprotkb/F6QX85" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [ { "pdb_id": "AF-F6QX85-F1", "pdb_chain": "global", "start_pos": 1, "end_pos": 583, "overlap": "1.0", "method": "AlphaFold", "type": "alphafold", "resolution": -1.0, "url": "https://data.glygen.org/ln2downloads/pdb/current/AF-F6QX85-F1.pdb", "url_external": "https://alphafold.ebi.ac.uk/entry/F6QX85" } ], "lectin_list": [], "domain_list": [], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" }, { "name": "homologset.oma", "label": "OMA Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [ 481 ], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 1 }, { "field": "total_sites", "count": 1 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 1 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": 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"total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ], "tool_support": { "graph_view": "yes" } }, { "uniprot_canonical_ac": "F6R4P6-1", "uniprot_ac": "F6R4P6", "uniprot_id": "F6R4P6_BOVIN", "mass": { "chemical_mass": 62705.0, "monoisotopic_mass": 62705.0 }, "refseq": {}, "gene_names": [ { "name": "SERPIND1", "type": "recommended", "evidence": [ { "id": "F6R4P6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F6R4P6" } ] } ], "protein_names": [ { "name": "Serpin family D member 1", "type": "synonym", "evidence": [ { "id": "F6R4P6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F6R4P6/entry#names_and_taxonomy" } ] } ], "function": [], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Bos taurus", "taxid": 9913, "evidence": [ { "database": "UniProtKB", "id": "F6R4P6", "url": 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"https://www.uniprot.org/uniprotkb/A0AAA9T4Z4", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0AAA9T4Z4-1", "url": "https://www.uniprot.org/uniprotkb/A0AAA9T4Z4-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "F6R4P6", "url": "https://www.uniprot.org/uniprotkb/F6R4P6", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "F6R4P6-1", "url": "https://www.uniprot.org/uniprotkb/F6R4P6-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MWSRSCWAVTRHTAGLCADEAGGRCSICDLCTLEDLDCSPAPKVTEERGRPWPIPPLQSHFAPAAQSSSGMWCPLRPLLLALLLASACRTLGPWGQRDDGGGEPESMEPRWGRLKGSNASGPLPPAAFHEENTVTGEWAADGEEEEDYLDLEKIFGEDDNYSDVVDAAPPTRPGAGAGSVLPLFPGKSRVQRLNLLNAQFAFDLYRALAARVGAADNVFLAPVGVSAAMAMLSLGLAGDTHQEVHTALRFAEFVNASAAYELGTVHNLFRKLIHRLFRRNFGYTLRSVSDLYVQKQLPVLDDFKTQVREYYFAEVRAADFSDPAFLAHTNRHVARLTKGLIRDALQDVDPATQMLLLNCLYFKGSWVNKFPVEMTHNHNFRLNEREVVKVPMMQTKGAFLAASDQELDCDVLRLEYVGGISMLVVVPHKLSGMKTLESQLTPQAVERWQRSMTNRTREVLLPKFKLEKDYDLVGALRALGVTALFDKHSNTTGITGQRIVIDLFKHQGTITVNEEGTQAAAVTAVGFMPLSTQVRFSVDRPFLFLIYEHRTSCLLFLGRVANPTRP", "length": 566, "header": "tr|F6R4P6-1|F6R4P6_BOVIN Isoform 1 of Serpin family D member 1 OS=Bos taurus OX=9913 GN=SERPIND1 PE=3 SV=1 CANONICAL=F6R4P6-1" }, "isoforms": [ { "isoform_ac": "A0A3Q1MAK6-1", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1MAK6/entry", "sequence": { "sequence": "MWSRSCWAVTRHTAGLCADEAGGRCSICDLCTLEDLDCSPAPKVTEERGRPWPIPPLQSHFAPAAQSSSGMWCPLRPLLLALLLASACRTLGPWGQRDDGGGEPESMEPRWGRLKGSNASGPLPPAAFHEENTVTGEWAADGEEEEDYLDLEKIFGEDDNYSDVVDAAPPTRPGAGAGSVLPLFPGKSRVQRLNLLNAQFAFDLYRALAARVGAADNVFLAPVGVSAAMAMLSLGLAGDTHQEVHTALRFAEFVNASAAYELGTVHNLFRKLIHRLFRRNFGYTLRSVSDLYVQKQLPVLDDFKTQVREYYFAEVRAADFSDPAFLAHTNRHVARLTKGLIRDALQDVDPATQMLLLNCLYFKGSWVNKFPVEMTHNHNFRLNEREVVKVPMMQTKGAFLAASDQELDCDVLRLEYVGGISMLVVVPHKLSGMKTLESQLTPQAVERWQRSMTNRTREVLLPKFKLEKDYDLVGALRALGVTALFDKHSNTTGITGQRIVIDLVTPALARPVWGGPPEPLPCLWTLGLPRRRPGDSHVAAVRTTEVTPFTPLHNTTPA", "length": 558, "header": "tr|A0A3Q1MAK6-1|F6R4P6_BOVIN Computationally mapped isoform of Serpin family D member 1 OS=Bos taurus OX=9913 GN=SERPIND1 PE=3 SV=2 CANONICAL=F6R4P6-1" }, "locus": { "chromosome": "17", "start_pos": 72238046, "end_pos": 72232163, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000086296.3", "url": "https://www.ensembl.org/id/ENSBTAT00000086296.3" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000071060.2", "url": "https://www.ensembl.org/id/ENSBTAP00000071060.2" } ] } }, { "isoform_ac": "A0AAA9T4Z4-1", "url": "https://www.uniprot.org/uniprotkb/A0AAA9T4Z4/entry", "sequence": { "sequence": "MWSRSCWAVTRHTAGLCADEAGGRCSICDLCTLEDLDCSPAPKVTEERGRPWPIPPLQSHFAPAAQSSSGMWCPLRPLLLALLLASACRTLGPWGQRDDGGGEPESMEPRWGRLKGSNASGPLPPAAFHEENTVTGEWAADGEEEEDYLDLEKIFGEDDNYSDVVDAAPPTRPGAGAGSVLPLFPGKSRVQRLNLLNAQFAFDLYRALAARVGAADNVFLAPVGVSAAMAMLSLGLAGDTHQEVHTALRFAEFVNASAAYELGTVHNLFRKLIHRLFRRNFGYTLRSVSDLYVQKQLPVLDDFKTQVREYYFAEVRAADFSDPAFLAHTNRHVARLTKGLIRDALQDVDPATQMLLLNCLYFKGSWVNKFPVEMTHNHNFRLNEREVVKVPMMQTKGAFLAASDQELDCDVLRLEYVGGISMLVVVPHKLSGMKTLESQLTPQAVERWQRSMTNRTREVLLPKFKLEKDYDLVGALRALGVTALFDKHSNTTGITGQRIVIDLVRFSVDRPFLFLIYEHRTSCLLFLGRVANPTRP", "length": 536, "header": "tr|A0AAA9T4Z4-1|F6R4P6_BOVIN Computationally mapped isoform of Serpin family D member 1 OS=Bos taurus OX=9913 GN=SERPIND1 PE=3 SV=1 CANONICAL=F6R4P6-1" }, "locus": { "chromosome": "17", "start_pos": 72238389, "end_pos": 72232163, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000134821.2", "url": "https://www.ensembl.org/id/ENSBTAT00000134821.2" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000091783.1", "url": "https://www.ensembl.org/id/ENSBTAP00000091783.1" } ] } }, { "isoform_ac": "F6R4P6-1", "url": "https://www.uniprot.org/uniprotkb/F6R4P6/entry", "sequence": { "sequence": "MWSRSCWAVTRHTAGLCADEAGGRCSICDLCTLEDLDCSPAPKVTEERGRPWPIPPLQSHFAPAAQSSSGMWCPLRPLLLALLLASACRTLGPWGQRDDGGGEPESMEPRWGRLKGSNASGPLPPAAFHEENTVTGEWAADGEEEEDYLDLEKIFGEDDNYSDVVDAAPPTRPGAGAGSVLPLFPGKSRVQRLNLLNAQFAFDLYRALAARVGAADNVFLAPVGVSAAMAMLSLGLAGDTHQEVHTALRFAEFVNASAAYELGTVHNLFRKLIHRLFRRNFGYTLRSVSDLYVQKQLPVLDDFKTQVREYYFAEVRAADFSDPAFLAHTNRHVARLTKGLIRDALQDVDPATQMLLLNCLYFKGSWVNKFPVEMTHNHNFRLNEREVVKVPMMQTKGAFLAASDQELDCDVLRLEYVGGISMLVVVPHKLSGMKTLESQLTPQAVERWQRSMTNRTREVLLPKFKLEKDYDLVGALRALGVTALFDKHSNTTGITGQRIVIDLFKHQGTITVNEEGTQAAAVTAVGFMPLSTQVRFSVDRPFLFLIYEHRTSCLLFLGRVANPTRP", "length": 566, "header": "tr|F6R4P6-1|F6R4P6_BOVIN Isoform 1 of Serpin family D member 1 OS=Bos taurus OX=9913 GN=SERPIND1 PE=3 SV=1 CANONICAL=F6R4P6-1" }, "locus": { "chromosome": "17", "start_pos": 72238389, "end_pos": 72232163, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000018574.7", "url": "https://www.ensembl.org/id/ENSBTAT00000018574.7" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000018574.6", "url": "https://www.ensembl.org/id/ENSBTAP00000018574.6" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [ { "id": "R-BTA-381426", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-BTA-381426", "resource": "Reactome", "description": "Regulation of Insulin-like Growth Factor (IGF) transport and uptake by Insulin-like Growth Factor Binding Proteins (IGFBPs)" }, { "id": "R-BTA-8957275", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-BTA-8957275", "resource": "Reactome", "description": "Post-translational protein phosphorylation" }, { "id": "R-BTA-9769733", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-BTA-9769733", "resource": "Reactome", "description": "Fibrin formation" }, { "id": "R-BTA-9769739", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-BTA-9769739", "resource": "Reactome", "description": "Regulation of clotting cascade" }, { "id": "R-BTA-9769743", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-BTA-9769743", "resource": "Reactome", "description": "Amplification and propagation of coagulation cascade" } ], "orthologs": [ { "uniprot_canonical_ac": "A0A481BLI9-1", "protein_name": "Serpin family D member 1", "gene_name": "SERPIND1", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MQRSPHPLMLFLLLASVCGKHGLVGQPVDGGEDPKSADPRWGQMKSRNQSRPLLPTDFHKDTVTNEWIADGEEDEDYLDLEKIFGDDDDYIDIVDAVSPADPMASAGNVLQLFPGKSRIQRLNILNAKFAFNLYRALKEQASASDNIFLAPVGISTAMGMLCLGLRGETHKQVHAALHFTDFVNASSKYELGTIHNLFRKLTHRLFRRDFGYTLRAVNDLYVQRQFPILDDFRTKVRQYYFAEVQAADFADPAFLSETNHHVARLTKGLIKDTLQDIDPATQMMILNCIYFKGSWVNKFPVEMTHNHNFRLNEREVVKVPMMQTKGAFLAASDQELDCEILQLDYVGGVSMLVVVPHKLSGMKTLEAQLTPQVVEKWQKSMTNRTREVLLPKFKLEKDYNLVEALRSVGVTALFDRNSNLTGISDQRIAIDLFKHHGTITVNEEGTQAAAVTTVGFMPLSTQARFSVDRPFLFLIHEHRTGCLLFMGRVANPARS", "length": 495 }, "evidence": [ { "id": "F6R4P6", "url": "https://omabrowser.org/oma/group/F6R4P6/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "A0A8V0ZRE8-1", "protein_name": "Serpin family D member 1", "gene_name": "SERPIND1", "tax_id": 9031, "organism": "Gallus gallus", "sequence": { "sequence": "MAVYSKRMKFLFPLLALAVIITSTFCGIKDFSDHFESLKDAHTHENGTYNMPDLPLEFHRENTITNDLIPEEEEEEDYLDLDKILGEDDYSDIIDAAPHIVSEIQQGNILELFQGKTRIQRLNILNANFGFNLYRSVADKANSSDNILMAPVGISTAMAMISLGLKGQTQQEVLSVLGFEDFINASAKYELMTVHNLFRKLTHRLFRRNFGYTLRSVNDLYIRKDFSILNDFRNNMKTYYFADAQPADFSDPNFITKTNERILKLTKGLIKEALVNVNPTTLMMILNCLYFKGTWENKFPVEMTTKRSFRLNEKQTIKVPMMQTKGNFLAAADPELDCGVIQLPFVGNISMLIVLPHKLSGMKALEKQITPQVVEKWQKSMTNRTREVVLPKFKLEKNYNLIGFLRSMGIEELFSEKGNYCGVSEEKVSIDRFNHQGTITVNEEGTEAGAITNVGFMPLSTQIRFIVDRPFLFLIYEHRTNCLLFMGRVVNPAKP", "length": 495 }, "evidence": [ { "id": "F6R4P6", "url": "https://omabrowser.org/oma/group/F6R4P6/", "database": "OMA" } ], "glygen_name": "Chicken", "common_name": "Chicken" }, { "uniprot_canonical_ac": "G3HFZ7-1", "protein_name": "Heparin cofactor 2", "gene_name": "Serpind1", "tax_id": 10029, "organism": "Cricetulus griseus", "sequence": { "sequence": "MKHPLHPLLLSVILSVCVGSNGLAEQVANENVSVSFLPANFHKENTVTNDWIPEGEEEDDYLDLEKLFSEDDDYIYIIDAVSPTDAESSAGNILQLFQGKSRIQRLNIINAKFAFNLYRVLKDKATTSENIFIAPVGISTAMGMLSLGLSGETHEEVHSVLHFKDFVNASSKYEITTIHNLFRKLTHRLFRRNFGYTLQSANGLYIQKQLPVREDFKADMREFYFAEAQVADFSDPAFILKANNHILKLTKGLIKAALENIDPATQMMILNCIYFKGTWVNKFPVEMTHSHNFRLNEREVIKVSMMQTKGNFLAASDQELDCDILQLEYVGGISMLIVIPRKLSGMKTLEAQLTPQVVERWQKSMTNRTREVLLPKFKLEKNYNLVEVLKSMGITKVFDKNGNMSGISDQRITVDLFKHQSTITVDEEGTQAAAVTTVGFMPLSTQVRFAVDRPFLFLVYEHRTSCLLFMGRVANPTRS", "length": 479 }, "evidence": [ { "id": "F6R4P6", "url": "https://omabrowser.org/oma/group/F6R4P6/", "database": "OMA" } ], "glygen_name": "Hamster", "common_name": "Chinese hamster" }, { "uniprot_canonical_ac": "P05546-1", "protein_name": "Heparin cofactor 2", "gene_name": "SERPIND1", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MKHSLNALLIFLIITSAWGGSKGPLDQLEKGGETAQSADPQWEQLNNKNLSMPLLPADFHKENTVTNDWIPEGEEDDDYLDLEKIFSEDDDYIDIVDSLSVSPTDSDVSAGNILQLFHGKSRIQRLNILNAKFAFNLYRVLKDQVNTFDNIFIAPVGISTAMGMISLGLKGETHEQVHSILHFKDFVNASSKYEITTIHNLFRKLTHRLFRRNFGYTLRSVNDLYIQKQFPILLDFKTKVREYYFAEAQIADFSDPAFISKTNNHIMKLTKGLIKDALENIDPATQMMILNCIYFKGSWVNKFPVEMTHNHNFRLNEREVVKVSMMQTKGNFLAANDQELDCDILQLEYVGGISMLIVVPHKMSGMKTLEAQLTPRVVERWQKSMTNRTREVLLPKFKLEKNYNLVESLKLMGIRMLFDKNGNMAGISDQRIAIDLFKHQGTITVNEEGTQATTVTTVGFMPLSTQVRFTVDRPFLFLIYEHRTSCLLFMGRVANPSRS", "length": 499 }, "evidence": [ { "id": "F6R4P6", "url": "https://omabrowser.org/oma/group/F6R4P6/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "P49182-1", "protein_name": "Heparin cofactor 2", "gene_name": "Serpind1", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MKHPLCTLLSLITFMCIGSKGLAEQLTNENLTTSFLPANFHKENTVTNDWIPEGEEDEDYLDLEKLLGEDDDYIYIIDAVSPTDSESSAGNILQLFQGKSRIQRLNILNAKFAFNLYRVLKDQATTSDNLFIAPVGISTAMGMISLGLRGETHEEVHSVLHFRDFVNASSKYEVTTIHNLFRKLTHRLFRRNFGYTLRSVNGLYIQKQFPIREDFKAAMREFYFAEAQEANFPDPAFISKANNHILKLTKGLIKEALENIDPATQMLILNCIYFKGTWVNKFPVEMTHNHNFRLNEREVVKVSMMQTKGNFLAANDQELDCDILQLEYVGGISMLIVVPRKLSGMKTLEAQLTPQVVERWQKSMTNRTREVLLPKFKLEKNYNLVEVLKSMGITKLFNKNGNMSGISDQRIAIDLFKHQSTITVNEEGTQAAAVTTVGFMPLSTQVRFTVDRPFLFLVYEHRTSCLLFMGKVTNPAKS", "length": 478 }, "evidence": [ { "id": "F6R4P6", "url": "https://omabrowser.org/oma/group/F6R4P6/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q64268-1", "protein_name": "Heparin cofactor 2", "gene_name": "Serpind1", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MKHPAYTLLLSLIMSMCAGSKGLAEQLTKENLTVSLLPPNFHKENTVTNDWIPEGEEDDDYLDLEKLLSEDDDYIYVVDAVSPTDSESSAGNILQLFQGKSRIQRLNILNAKFAFNLYRVLKDQATSSDNIFIAPVGISTAMGMISLGLRGETHEEVHSVLHFKDFVNASSKYEVTTIHNLFRKLTHRLFRRNFGYTLQSVNDLYIQKQFPIREDFKAAMREFYFAEAQEADFSDPAFISKANSHILKLTKGLIKEALENTDSATQMMILNCIYFKGAWMNKFPVEMTHNHNFRLNEREVVKVSMMQTKGNFLAANDQELDCDILQLEYVGGISMLIVIPRKLSGMKTLEAQLTPQVVERWQKSMTNRTREVLLPKFKLEKNYNLVEVLKSMGITKLFNKNGNMSGISDQRIIIDLFKHQSTITVNEEGTQAAAVTTVGFMPLSTQVRFTVDRPFLFLVYEHRTSCLLFMGRVANPAKS", "length": 479 }, "evidence": [ { "id": "F6R4P6", "url": "https://omabrowser.org/oma/group/F6R4P6/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" } ], "go_annotation": { "categories": [ { "name": "Molecular Function", "total": 1, "go_terms": [ { "name": "serine-type endopeptidase inhibitor activity", "id": "GO:0004867", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0004867", "evidence": [ { "database": "UniProtKB", "id": "F6R4P6", "url": "https://www.uniprot.org/uniprotkb/F6R4P6" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 1, "go_terms": [ { "name": "extracellular space", "id": "GO:0005615", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005615", "evidence": [ { "database": "UniProtKB", "id": "F6R4P6", "url": "https://www.uniprot.org/uniprotkb/F6R4P6" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 1, "go_terms": [ { "name": "blood coagulation", "id": "GO:0007596", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007596", "evidence": [ { "database": "UniProtKB", "id": "F6R4P6", "url": "https://www.uniprot.org/uniprotkb/F6R4P6" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 118, "end_pos": 120, "annotation": "n_glycosylation_sequon" }, { "start_pos": 160, "end_pos": 162, "annotation": "n_glycosylation_sequon" }, { "start_pos": 255, "end_pos": 257, "annotation": "n_glycosylation_sequon" }, { "start_pos": 454, "end_pos": 456, "annotation": "n_glycosylation_sequon" }, { "start_pos": 490, "end_pos": 492, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [ { "pdb_id": "AF-F6R4P6-F1", "pdb_chain": "global", "start_pos": 1, "end_pos": 566, "overlap": "1.0", "method": "AlphaFold", "type": "alphafold", "resolution": -1.0, "url": "https://data.glygen.org/ln2downloads/pdb/current/AF-F6R4P6-F1.pdb", "url_external": "https://alphafold.ebi.ac.uk/entry/F6R4P6" } ], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "F6R4P6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F6R4P6" }, { "id": "SM00093", "database": "SMART", "url": "http://smart.embl.de/smart/do_annotation.pl?DOMAIN=SM00093" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "Serpin", "eco_id": "ECO_0000259", "start_pos": 202, "end_pos": 563, "start_aa": "Phe", "end_aa": "Pro", "glycosite_overlap": [] } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" }, { "name": "homologset.oma", "label": "OMA Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 118, "end_pos": 120 }, { "start_pos": 160, "end_pos": 162 }, { "start_pos": 255, "end_pos": 257 }, { "start_pos": 454, "end_pos": 456 }, { "start_pos": 490, "end_pos": 492 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": 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} ], "protein_names": [ { "name": "ER membrane protein complex subunit 8", "type": "synonym", "evidence": [ { "id": "F1N5N2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1N5N2/entry#names_and_taxonomy" } ] } ], "function": [], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Bos taurus", "taxid": 9913, "evidence": [ { "database": "UniProtKB", "id": "F1N5N2", "url": "https://www.uniprot.org/uniprotkb/F1N5N2" } ], "common_name": "Bovine", "glygen_name": "Bovine", "reference_species": "Bos taurus [9913]" } ], "gene": [ { "name": "EMC8", "url": "https://www.uniprot.org/uniprotkb/F1N5N2", "locus": { "chromosome": "18", "start_pos": 11747957, "end_pos": 11759716, "strand": "+", "evidence": [ { "database": "Ensembl Gene", "id": "ENSBTAG00000016075", "url": "https://www.ensembl.org/id/ENSBTAG00000016075" } ] } } ], "crossref": [ { "id": "F1N5N2", "url": "https://alphafold.ebi.ac.uk/entry/F1N5N2", "database": "AlphaFoldDB", "categories": [] }, { "id": "ENSBTAG00000016075", "url": "https://bgee.org/?page=gene&gene_id=ENSBTAG00000016075", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "cd08060", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd08060", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "IPR005366", "url": "https://www.ebi.ac.uk/interpro/entry/IPR005366", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR037518", "url": "https://www.ebi.ac.uk/interpro/entry/IPR037518", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "PHCAING", "url": "https://omabrowser.org/oma/group/PHCAING/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "A0A3Q1MAT3", "url": "https://www.orthodb.org/?gene=A0A3Q1MAT3", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "F1N5N2", "url": "https://www.orthodb.org/?gene=F1N5N2", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR12941", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR12941", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR12941:SF13", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR12941:SF13", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF03665", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF03665", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "A0A3Q1MAT3", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1MAT3", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A3Q1MAT3-1", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1MAT3-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0AAA9T354", "url": "https://www.uniprot.org/uniprotkb/A0AAA9T354", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0AAA9T354-1", "url": "https://www.uniprot.org/uniprotkb/A0AAA9T354-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "F1N5N2", "url": "https://www.uniprot.org/uniprotkb/F1N5N2", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "F1N5N2-1", "url": "https://www.uniprot.org/uniprotkb/F1N5N2-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MPGVKLTTQAYCKMVLHGAKYPHCAVNGLLVAEKQKPRKEHLPLGGPGAHHTLFVDCIPLFHGTLALAPMLEVALTLIDSWCKDNSYVIAGYYQANERVKDASPNQVAEKVASRIAEGFSDTALIMVDNTKFTMDCVVPTIHVYEHHENKWRCRDPHYDYCEDWPEAQRISASLLDSRSYETLVDFDNHLDDIRNDWTNPEINKAVLHLC", "length": 210, "header": "tr|F1N5N2-1|F1N5N2_BOVIN Isoform 1 of ER membrane protein complex subunit 8 OS=Bos taurus OX=9913 GN=EMC8 PE=3 SV=1 CANONICAL=F1N5N2-1" }, "isoforms": [ { "isoform_ac": "A0A3Q1MAT3-1", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1MAT3/entry", "sequence": { "sequence": "MPGVKLTTQAYCKMVLHGAKYPHCAVNGLLVAEKQKPRKEHLPLGGPGAHHTLFVDCIPLFHGTLALAPMLEVALTLIDSWCKDNSYVIAGYYQANERVKDARDPQAAAEVLALFASAPFVSLQVDNTKFTMDCVVPTIHVYEHHENKWRCRDPHYDYCEDWPEAQRISASLLDSRSYETLVDFDNHLDDIRNDWTNPEINKAVLHLC", "length": 208, "header": "tr|A0A3Q1MAT3-1|F1N5N2_BOVIN Computationally mapped isoform of ER membrane protein complex subunit 8 OS=Bos taurus OX=9913 GN=EMC8 PE=3 SV=1 CANONICAL=F1N5N2-1" }, "locus": { "chromosome": "18", "start_pos": 11759493, "end_pos": 11748268, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000082292.2", "url": "https://www.ensembl.org/id/ENSBTAT00000082292.2" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000067741.1", "url": "https://www.ensembl.org/id/ENSBTAP00000067741.1" } ] } }, { "isoform_ac": "A0AAA9T354-1", "url": "https://www.uniprot.org/uniprotkb/A0AAA9T354/entry", "sequence": { "sequence": "MPGVKLTTQAYCKMVLHGAKYPHCAVNGLLVAEKQKPRKEHLPLGGPGAHHTLFVDCIPLFHGTLALAPMLEVALTLIDSWCKDNSYVIAGYYQANERVKDASPNQVAEKVASRIAEGFSDTALIM", "length": 126, "header": "tr|A0AAA9T354-1|F1N5N2_BOVIN Computationally mapped isoform of ER membrane protein complex subunit 8 OS=Bos taurus OX=9913 GN=EMC8 PE=3 SV=1 CANONICAL=F1N5N2-1" }, "locus": { "chromosome": "18", "start_pos": 11759493, "end_pos": 11749761, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000101669.1", "url": "https://www.ensembl.org/id/ENSBTAT00000101669.1" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000093211.1", "url": "https://www.ensembl.org/id/ENSBTAP00000093211.1" } ] } }, { "isoform_ac": "F1N5N2-1", "url": "https://www.uniprot.org/uniprotkb/F1N5N2/entry", "sequence": { "sequence": "MPGVKLTTQAYCKMVLHGAKYPHCAVNGLLVAEKQKPRKEHLPLGGPGAHHTLFVDCIPLFHGTLALAPMLEVALTLIDSWCKDNSYVIAGYYQANERVKDASPNQVAEKVASRIAEGFSDTALIMVDNTKFTMDCVVPTIHVYEHHENKWRCRDPHYDYCEDWPEAQRISASLLDSRSYETLVDFDNHLDDIRNDWTNPEINKAVLHLC", "length": 210, "header": "tr|F1N5N2-1|F1N5N2_BOVIN Isoform 1 of ER membrane protein complex subunit 8 OS=Bos taurus OX=9913 GN=EMC8 PE=3 SV=1 CANONICAL=F1N5N2-1" }, "locus": { "chromosome": "18", "start_pos": 11759493, "end_pos": 11748268, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000021393.3", "url": "https://www.ensembl.org/id/ENSBTAT00000021393.3" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000021393.2", "url": "https://www.ensembl.org/id/ENSBTAP00000021393.2" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [], "orthologs": [ { "uniprot_canonical_ac": "F1N8E6-1", "protein_name": "ER membrane protein complex subunit 8", "gene_name": "EMC8", "tax_id": 9031, "organism": "Gallus gallus", "sequence": { "sequence": "MKLTTQAYCKMVLHGAKYPHCAVNGLLVAERPPGSRGREQAGPPSLFVDCIPLFHGTLALAPMLEVALTLIDSWCKENSYVIAGYYQANERVKDASPTQVAEKVASRIAEGFNDTALIMVDNTKFTMECLEPAIHVYELHENKWRCKDPHVDFCEDWSEAQRIAASLLDSKSYETLVDFDNHLDDIRNDWTNPEINKAVLHLC", "length": 203 }, "evidence": [ { "id": "F1N5N2", "url": "https://omabrowser.org/oma/group/F1N5N2/", "database": "OMA" } ], "glygen_name": "Chicken", "common_name": "Chicken" }, { "uniprot_canonical_ac": "O43402-1", "protein_name": "ER membrane protein complex subunit 8", "gene_name": "EMC8", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MPGVKLTTQAYCKMVLHGAKYPHCAVNGLLVAEKQKPRKEHLPLGGPGAHHTLFVDCIPLFHGTLALAPMLEVALTLIDSWCKDHSYVIAGYYQANERVKDASPNQVAEKVASRIAEGFSDTALIMVDNTKFTMDCVAPTIHVYEHHENRWRCRDPHHDYCEDWPEAQRISASLLDSRSYETLVDFDNHLDDIRNDWTNPEINKAVLHLC", "length": 210 }, "evidence": [ { "id": "F1N5N2", "url": "https://omabrowser.org/oma/group/F1N5N2/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "O70378-1", "protein_name": "ER membrane protein complex subunit 8", "gene_name": "Emc8", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MPGVKLTTQAYCKMVLHGAKYPHCAVNGLLVAERQRPRKEHPPGAGSHTLFVDCIPLFHGTLALTPMLEVALTLIDSWCKDNSYVIAGYYQANERVKDASPNQVAEKVASRIAEGFGDAALIMVDNAKFTMDCAAPTIHVYEQHENRWRCRDPHHDYCEDWPEAQRISASLLDSRSYETLVDFDNHLDDIRSDWTNPEINKAVLHLC", "length": 207 }, "evidence": [ { "id": "F1N5N2", "url": "https://omabrowser.org/oma/group/F1N5N2/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q55FM0-1", "protein_name": "ER membrane protein complex subunit 8/9 homolog", "gene_name": "", "tax_id": 44689, "organism": "Dictyostelium discoideum", "sequence": { "sequence": "MNNNISITTEALSKAHLHSFKHHASSVNGILLGKADKNSILITDIIPLFHTQTLLPMFEVAMIQIEKYCRDNNIDMVGYYHSNQCIANELEPEPIAKKIADRLNNELNNMCFLMISKIEVNRPSGLVSIDKVGSDWLKNRKTLITIDTTSNSEDINEILKRNLQNIKESQIYDFEEYLSNPTRDWLNKSLVL", "length": 192 }, "evidence": [ { "id": "F1N5N2", "url": "https://omabrowser.org/oma/group/F1N5N2/", "database": "OMA" } ], "glygen_name": "Cellular slime mold", "common_name": "Social amoeba" }, { "uniprot_canonical_ac": "Q9FG71-1", "protein_name": "ER membrane protein complex subunit 8/9 homolog", "gene_name": "EMB2731", "tax_id": 3702, "organism": "Arabidopsis thaliana", "sequence": { "sequence": "MGMGSNGELKYEISQNAYIKLVLHSLRHKTAAVNGVLVGRISPKDDGVVEISDSVPLFHSNLALLPPLEISLIMIEEHYVAQGLSIVGYFHANERFDDVELCGVAKNIGDHISRYFPQAPILLLNNKKLEALSKGKERSPVMQLCVKDASKNWRVVGADGGSKLLLKEPSANVVLSDYISSEKWKDVTDVDDHLDDVTKDWLNPGLFN", "length": 208 }, "evidence": [ { "id": "F1N5N2", "url": "https://omabrowser.org/oma/group/F1N5N2/", "database": "OMA" } ], "glygen_name": "Arabidopsis", "common_name": "Mouse-ear cress" }, { "uniprot_canonical_ac": "Q9W1Y1-1", "protein_name": "ER membrane protein complex subunit 8/9 homolog", "gene_name": "EMC8-9", "tax_id": 7227, "organism": "Drosophila melanogaster", "sequence": { "sequence": "MCDYKVSERAYAKLIFHAAKYPHQAVNGLLLAEKTSKGSQVEIVDAIPLFHQCLYVTPMAEVALMLIDAHAEREGLVIAGYYAAPENFYDNQVDKTPAAKIADKIQENFKNACFVVVDNKLMTLQHDRAAIQVFNCPGDSGARWSKAKFTLSQASDTLEGVSLLLKRGAMRDLVDFDNHLDNPDKNWTNDFLNQPLNDLQKLY", "length": 203 }, "evidence": [ { "id": "F1N5N2", "url": "https://omabrowser.org/oma/group/F1N5N2/", "database": "OMA" } ], "glygen_name": "Fruit fly", "common_name": "Fruit fly" } ], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 1, "go_terms": [ { "name": "EMC complex", "id": "GO:0072546", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0072546", "evidence": [ { "database": "UniProtKB", "id": "F1N5N2", "url": "https://www.uniprot.org/uniprotkb/F1N5N2" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 2, "go_terms": [ { "name": "tail-anchored membrane protein insertion into ER membrane", "id": "GO:0071816", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0071816", "evidence": [ { "database": "UniProtKB", "id": "F1N5N2", "url": "https://www.uniprot.org/uniprotkb/F1N5N2" } ], "pmid": "" }, { "name": "protein insertion into ER membrane by stop-transfer membrane-anchor sequence", "id": "GO:0045050", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0045050", "evidence": [ { "database": "UniProtKB", "id": "F1N5N2", "url": "https://www.uniprot.org/uniprotkb/F1N5N2" } ], "pmid": "" } ] }, { "name": "Molecular Function", "total": 1, "go_terms": [ { "name": "membrane insertase activity", "id": "GO:0032977", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0032977", "evidence": [ { "database": "UniProtKB", "id": "F1N5N2", "url": "https://www.uniprot.org/uniprotkb/F1N5N2" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [ { "pdb_id": "AF-F1N5N2-F1", "pdb_chain": "global", "start_pos": 1, "end_pos": 210, "overlap": "1.0", "method": "AlphaFold", "type": "alphafold", "resolution": -1.0, "url": "https://data.glygen.org/ln2downloads/pdb/current/AF-F1N5N2-F1.pdb", "url_external": "https://alphafold.ebi.ac.uk/entry/F1N5N2" } ], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "F1N5N2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1N5N2" }, { "id": "PS50249", "database": "PROSITE", "url": "https://prosite.expasy.org/PS50249" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "MPN", "eco_id": "ECO_0000259", "start_pos": 4, "end_pos": 150, "start_aa": "Val", "end_aa": "Lys", "glycosite_overlap": [] } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" }, { "name": "homologset.oma", "label": "OMA Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { 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"total", "count": 0 } ], "sort_fields": [] } ], "tool_support": { "graph_view": "yes" } }, { "uniprot_canonical_ac": "F6Q0E0-1", "uniprot_ac": "F6Q0E0", "uniprot_id": "F6Q0E0_BOVIN", "mass": { "chemical_mass": 46490.0, "monoisotopic_mass": 46490.0 }, "refseq": {}, "gene_names": [ { "name": "GATD3", "type": "recommended", "evidence": [ { "id": "F6Q0E0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F6Q0E0" } ] } ], "protein_names": [ { "name": "Glutamine amidotransferase class 1 domain containing 3", "type": "synonym", "evidence": [ { "id": "F6Q0E0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F6Q0E0/entry#names_and_taxonomy" } ] } ], "function": [], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Bos taurus", "taxid": 9913, "evidence": [ { "database": "UniProtKB", "id": "F6Q0E0", "url": "https://www.uniprot.org/uniprotkb/F6Q0E0" } ], "common_name": "Bovine", "glygen_name": "Bovine", "reference_species": "Bos taurus [9913]" } ], "gene": [ { "name": "GATD3", "url": "https://www.uniprot.org/uniprotkb/F6Q0E0", "locus": {} } ], "crossref": [ { "id": "F6Q0E0", "url": "https://alphafold.ebi.ac.uk/entry/F6Q0E0", "database": "AlphaFoldDB", "categories": [] }, { "id": "ENSBTAG00000007106", "url": "https://bgee.org/?page=gene&gene_id=ENSBTAG00000007106", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "cd03133", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd03133", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "IPR029062", "url": "https://www.ebi.ac.uk/interpro/entry/IPR029062", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "PTHR10224", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR10224", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR10224:SF9", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR10224:SF9", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "A0A3Q1MDT8", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1MDT8", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A3Q1MDT8-1", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1MDT8-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0AAA9SB15", "url": "https://www.uniprot.org/uniprotkb/A0AAA9SB15", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0AAA9SB15-1", "url": "https://www.uniprot.org/uniprotkb/A0AAA9SB15-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "F6Q0E0", "url": "https://www.uniprot.org/uniprotkb/F6Q0E0", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "F6Q0E0-1", "url": "https://www.uniprot.org/uniprotkb/F6Q0E0-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MRAGQAGASHSVTPVRLRSYGDTEVNFPEPVSQHVISRGLRPCVVPPRENRRGEATALETAQTTWDHLHSRGGARLPGYCAGAAPPTVTCDPVLAQHGGVQGSGGGKAGGDPRVRAASRPVAAALRRTGALLARGLPRLRAAPRAQGCSGERTRAPGEIGTWGRGGRAPRSAFPPSLPAVGSSAPTPSLGYPALPRPRSRPLPTLEAVGRPADPLTLVTGPPSPQVLSGCGVYDGTELHEASSILVHLSRGGAEVQIFAPDVPQMHVIDHIKGQPSEGETRNVLTESARIARGKITDLAKLTAVNHDAAIFPGGFGAAKNLSTFAVDGGTCKVNRDVERVLKEFHQAGKPIGLCCIAPVLAAKVLRGVEVTVGHEQEEGGKWPHAGTAEVIKALGAKHCVMGVTEAHVDQKNKVVTTPAFMCDTALHHIHDGIGAMVRKVLELAGR", "length": 446, "header": "tr|F6Q0E0-1|F6Q0E0_BOVIN Isoform 1 of Glutamine amidotransferase class 1 domain containing 3 OS=Bos taurus OX=9913 GN=GATD3 PE=1 SV=1 CANONICAL=F6Q0E0-1" }, "isoforms": [ { "isoform_ac": "A0A3Q1MDT8-1", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1MDT8/entry", "sequence": { "sequence": "MAAFRALAAARLAVTPGFAPRPGLWPLPFGGPAPSSRAAFHASAPRPGPRVAVVLSGCGVYDGTELHEASSILVHLSRGGAEVQIFAPDVPQMHVIDHIKGQPSEGETRNVLTESARIARGKITDLAKLTAVNHDAAIFPGGFGAAKNLSTFAVDGGTCKVNRDVERVLKEFHQAGKPIGSGLLTSCFQAACPSLLGLLVRIMDGVGVQPALCQASAFIPALQEPLEACTSASPADLCCIAPVLAAKVLRGVEVTVGHEQEEGGKWPHAGTAEVIKALGAKHCVMGVTISFQQPAWRGDPLRPLGAALGHCRVWVPRAPE", "length": 320, "header": "tr|A0A3Q1MDT8-1|F6Q0E0_BOVIN Computationally mapped isoform of Glutamine amidotransferase class 1 domain containing 3 OS=Bos taurus OX=9913 GN=GATD3 PE=1 SV=2 CANONICAL=F6Q0E0-1" }, "locus": { "chromosome": "1", "start_pos": 144157090, "end_pos": 144149318, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000087382.3", "url": "https://www.ensembl.org/id/ENSBTAT00000087382.3" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000067015.2", "url": "https://www.ensembl.org/id/ENSBTAP00000067015.2" } ] } }, { "isoform_ac": "A0AAA9SB15-1", "url": "https://www.uniprot.org/uniprotkb/A0AAA9SB15/entry", "sequence": { "sequence": "MAAFRALAAARLAVTPGFAPRPGLWPLPFGGPAPSSRAAFHASAPRPGPRVAVVLSGCGVYDGTELHEASSILVHLSRGGAEVQIFAPDVPQMHVIDHIKGQPSEGETRNVLTESARIARGKITDLAKLTAVNHDAAIFPGGFGAAKNLSTFAVDGGTCKVNRDVERVLKEFHQAGKPIGLCCIAPVLAAKVLRGVEVTVGHEQEEGGKWPHAGTAEVIKALGAKHCVMGVTISFQQPAWRGDPLRPLGAALGHCRVWVPRAPE", "length": 264, "header": "tr|A0AAA9SB15-1|F6Q0E0_BOVIN Computationally mapped isoform of Glutamine amidotransferase class 1 domain containing 3 OS=Bos taurus OX=9913 GN=GATD3 PE=1 SV=1 CANONICAL=F6Q0E0-1" }, "locus": { "chromosome": "1", "start_pos": 144157090, "end_pos": 144149318, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000111775.2", "url": "https://www.ensembl.org/id/ENSBTAT00000111775.2" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000081093.1", "url": "https://www.ensembl.org/id/ENSBTAP00000081093.1" } ] } }, { "isoform_ac": "F6Q0E0-1", "url": "https://www.uniprot.org/uniprotkb/F6Q0E0/entry", "sequence": { "sequence": "MRAGQAGASHSVTPVRLRSYGDTEVNFPEPVSQHVISRGLRPCVVPPRENRRGEATALETAQTTWDHLHSRGGARLPGYCAGAAPPTVTCDPVLAQHGGVQGSGGGKAGGDPRVRAASRPVAAALRRTGALLARGLPRLRAAPRAQGCSGERTRAPGEIGTWGRGGRAPRSAFPPSLPAVGSSAPTPSLGYPALPRPRSRPLPTLEAVGRPADPLTLVTGPPSPQVLSGCGVYDGTELHEASSILVHLSRGGAEVQIFAPDVPQMHVIDHIKGQPSEGETRNVLTESARIARGKITDLAKLTAVNHDAAIFPGGFGAAKNLSTFAVDGGTCKVNRDVERVLKEFHQAGKPIGLCCIAPVLAAKVLRGVEVTVGHEQEEGGKWPHAGTAEVIKALGAKHCVMGVTEAHVDQKNKVVTTPAFMCDTALHHIHDGIGAMVRKVLELAGR", "length": 446, "header": "tr|F6Q0E0-1|F6Q0E0_BOVIN Isoform 1 of Glutamine amidotransferase class 1 domain containing 3 OS=Bos taurus OX=9913 GN=GATD3 PE=1 SV=1 CANONICAL=F6Q0E0-1" }, "locus": { "chromosome": "1", "start_pos": 144157650, "end_pos": 144149029, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000009346.6", "url": "https://www.ensembl.org/id/ENSBTAT00000009346.6" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000009346.5", "url": "https://www.ensembl.org/id/ENSBTAP00000009346.5" } ] } } ], "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "other", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 186, "start_aa": "Thr", "end_pos": 186, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr186", "evidence": [ { "id": "", "database": "GlyGen", "url": "https://data.glygen.org/" } ], "filter_code": "000000000000000010000.00000000001000.0.01000" } ], "phosphorylation": [], "glycation": [], "keywords": [ "glycoprotein", "glycoprotein_predicted" ], "publication": [], "pathway": [], "orthologs": [], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 1, "go_terms": [ { "name": "mitochondrion", "id": "GO:0005739", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005739", "evidence": [ { "database": "UniProtKB", "id": "F6Q0E0", "url": "https://www.uniprot.org/uniprotkb/F6Q0E0" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 320, "end_pos": 322, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [ 186 ], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 320, "end_pos": 322 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 1 }, { "field": "total_sites", "count": 1 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 1 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "exact_sites", "count": 1 }, { "field": "exact_o_linked_sites", "count": 1 }, { "field": "fuzzy_sites", "count": 0 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_pos", "start_aa", "end_pos", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 1 }, { "field": "total_sites", "count": 1 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 1 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "exact_sites", "count": 1 }, { "field": "exact_o_linked_sites", "count": 1 }, { "field": "fuzzy_sites", "count": 0 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_pos", "start_aa", "end_pos", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ], "tool_support": { "graph_view": "yes" } }, { "uniprot_canonical_ac": "F6PXW3-1", "uniprot_ac": "F6PXW3", "uniprot_id": "F6PXW3_BOVIN", "mass": { "chemical_mass": 48557.0, "monoisotopic_mass": 48557.0 }, "refseq": { "ac": "XP_005201730", "name": "actin-related protein T3 isoform X1", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_005201730" }, "gene_names": [ { "name": "ACTRT3", "type": "recommended", "evidence": [ { "id": "F6PXW3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F6PXW3" } ] }, { "name": "ACTRT3", "type": "synonym", "evidence": [ { "id": "XP_005201730", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_005201730" } ] }, { "name": "ARPM1", "type": "synonym", "evidence": [ { "id": "XP_005201730", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_005201730" } ] } ], "protein_names": [ { "name": "Actin related protein T3", "type": "synonym", "evidence": [ { "id": "F6PXW3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F6PXW3/entry#names_and_taxonomy" } ] }, { "name": "actin-related protein T3 isoform X1", "type": "synonym", "evidence": [ { "id": "XP_005201730", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_005201730" } ] } ], "function": [], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Bos taurus", "taxid": 9913, "evidence": [ { "database": "UniProtKB", "id": "F6PXW3", "url": "https://www.uniprot.org/uniprotkb/F6PXW3" } ], "common_name": "Bovine", "glygen_name": "Bovine", "reference_species": "Bos taurus [9913]" } ], "gene": [ { "name": "ACTRT3", "url": "https://www.uniprot.org/uniprotkb/F6PXW3", "locus": { "chromosome": "1", "start_pos": 97609709, "end_pos": 97604155, "strand": "-", "evidence": [ { "database": "Ensembl Gene", "id": "ENSBTAG00000013141", "url": "https://www.ensembl.org/id/ENSBTAG00000013141" } ] } } ], "crossref": [ { "id": "F6PXW3", "url": "https://alphafold.ebi.ac.uk/entry/F6PXW3", "database": "AlphaFoldDB", "categories": [] }, { "id": "ENSBTAG00000013141", "url": "https://bgee.org/?page=gene&gene_id=ENSBTAG00000013141", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "cd13397", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd13397", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "509723", "url": "https://www.ncbi.nlm.nih.gov/gene/509723", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR004000", "url": "https://www.ebi.ac.uk/interpro/entry/IPR004000", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR043129", "url": "https://www.ebi.ac.uk/interpro/entry/IPR043129", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "WEDMEIM", "url": "https://omabrowser.org/oma/group/WEDMEIM/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "F6PXW3", "url": "https://www.orthodb.org/?gene=F6PXW3", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR11937", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR11937", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00022", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00022", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "XP_005201730", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_005201730", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A3Q1MDW6", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1MDW6", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A3Q1MDW6-1", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1MDW6-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0AAA9S9Y8", "url": "https://www.uniprot.org/uniprotkb/A0AAA9S9Y8", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0AAA9S9Y8-1", "url": "https://www.uniprot.org/uniprotkb/A0AAA9S9Y8-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "F6PXW3", "url": "https://www.uniprot.org/uniprotkb/F6PXW3", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "F6PXW3-1", "url": "https://www.uniprot.org/uniprotkb/F6PXW3-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MRLGKEIDKVLFQEFEKHEPCPALYDTFLVQISAPFVDFKGASDNFPQEPGQASRSQGSPSSRETGGGGGGMSYYQLPVVIDNGSGVIKAGLAGSREPQFVYSNIVGRTKGLTCGVEVCVGDQAEQRRSSLSISYPVERGLITSWGDMEIMWKHIYDDNLRLKPCDGPVLITESALNPLANRQRVTEVFFEYLEVPAFFMSVQGVLALFAAGFTTGFVLNSGAGVTQCVPIFEGYCLPHGVQQLDLAGLDLTNYLMMLLKENGIMLLRTSERKIITDIKETYCYVAMNFEEEKAKKADCIEKIYQLPDGKRFKLHNQLFYCPEALFSPSLMHLETPGIDKMCFSSIMKCDADLRNAFFSNIILAGGSTSFPGLEKRLVKDIAKMVPANTPVQVIAPPERKISVWMGGSILASLSAFQDMWITAAEYKEVGSNIVHQRCF", "length": 439, "header": "tr|F6PXW3-1|F6PXW3_BOVIN Isoform 1 of Actin related protein T3 OS=Bos taurus OX=9913 GN=ACTRT3 PE=3 SV=1 CANONICAL=F6PXW3-1" }, "isoforms": [ { "isoform_ac": "A0A3Q1MDW6-1", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1MDW6/entry", "sequence": { "sequence": "MRLGKARSQGSPSSRETGGGGGGMSYYQLPVVIDNGSGVIKAGLAGSREPQFVYSNIVGRTKGLTCGVEVCVGDQAEQRRSSLSISYPVERGLITSWGDMEIMWKHIYDDNLRLKPCDGPVLITESALNPLANRQRVTEVFFEYLEVPAFFMSVQGVLALFAAGFTTGFVLNSGAGVTQCVPIFEGYCLPHGVQQLDLAGLDLTNYLMMLLKENGIMLLRTSERKIITDIKETYCYVAMNFEEEKAKKADCIEKIYQLPDGKRFKLHNQLFYCPEALFSPSLMHLETPGIDKMCFSSIMKCDADLRNAFFSNIILAGGSTSFPGLEKRLVKDIAKMVPANTPVQVIAPPERKISVWMGGSILASLSAFQDMWITAAEYKEVGSNIVHQRCF", "length": 391, "header": "tr|A0A3Q1MDW6-1|F6PXW3_BOVIN Computationally mapped isoform of Actin related protein T3 OS=Bos taurus OX=9913 GN=ACTRT3 PE=3 SV=1 CANONICAL=F6PXW3-1" }, "locus": { "chromosome": "1", "start_pos": 97609503, "end_pos": 97604766, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000071730.3", "url": "https://www.ensembl.org/id/ENSBTAT00000071730.3" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000068652.2", "url": "https://www.ensembl.org/id/ENSBTAP00000068652.2" } ] } }, { "isoform_ac": "A0AAA9S9Y8-1", "url": "https://www.uniprot.org/uniprotkb/A0AAA9S9Y8/entry", "sequence": { "sequence": "MNLAPPYTTLSWFKSLHLLSISRAHLITSRRSLDRPRSQGSPSSRETGGGGGGMSYYQLPVVIDNGSGVIKAGLAGSREPQFVYSNIVGRTKGLTCGVEVCVGDQAEQRRSSLSISYPVERGLITSWGDMEIMWKHIYDDNLRLKPCDGPVLITESALNPLANRQRVTEVFFEYLEVPAFFMSVQGVLALFAAGFTTGFVLNSGAGVTQCVPIFEGYCLPHGVQQLDLAGLDLTNYLMMLLKENGIMLLRTSERKIITDIKETYCYVAMNFEEEKAKKADCIEKIYQLPDGKRFKLHNQLFYCPEALFSPSLMHLETPGIDKMCFSSIMKCDADLRNAFFSNIILAGGSTSFPGLEKRLVKDIAKMVPANTPVQVIAPPERKISVWMGGSILASLSAFQDMWITAAEYKEVGSNIVHQRCF", "length": 421, "header": "tr|A0AAA9S9Y8-1|F6PXW3_BOVIN Computationally mapped isoform of Actin related protein T3 OS=Bos taurus OX=9913 GN=ACTRT3 PE=3 SV=1 CANONICAL=F6PXW3-1" }, "locus": { "chromosome": "1", "start_pos": 97609503, "end_pos": 97607097, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000110641.2", "url": "https://www.ensembl.org/id/ENSBTAT00000110641.2" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000082123.1", "url": "https://www.ensembl.org/id/ENSBTAP00000082123.1" } ] } }, { "isoform_ac": "F6PXW3-1", "url": "https://www.uniprot.org/uniprotkb/F6PXW3/entry", "sequence": { "sequence": "MRLGKEIDKVLFQEFEKHEPCPALYDTFLVQISAPFVDFKGASDNFPQEPGQASRSQGSPSSRETGGGGGGMSYYQLPVVIDNGSGVIKAGLAGSREPQFVYSNIVGRTKGLTCGVEVCVGDQAEQRRSSLSISYPVERGLITSWGDMEIMWKHIYDDNLRLKPCDGPVLITESALNPLANRQRVTEVFFEYLEVPAFFMSVQGVLALFAAGFTTGFVLNSGAGVTQCVPIFEGYCLPHGVQQLDLAGLDLTNYLMMLLKENGIMLLRTSERKIITDIKETYCYVAMNFEEEKAKKADCIEKIYQLPDGKRFKLHNQLFYCPEALFSPSLMHLETPGIDKMCFSSIMKCDADLRNAFFSNIILAGGSTSFPGLEKRLVKDIAKMVPANTPVQVIAPPERKISVWMGGSILASLSAFQDMWITAAEYKEVGSNIVHQRCF", "length": 439, "header": "tr|F6PXW3-1|F6PXW3_BOVIN Isoform 1 of Actin related protein T3 OS=Bos taurus OX=9913 GN=ACTRT3 PE=3 SV=1 CANONICAL=F6PXW3-1" }, "locus": { "chromosome": "1", "start_pos": 97609503, "end_pos": 97604766, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000017467.6", "url": "https://www.ensembl.org/id/ENSBTAT00000017467.6" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000017467.4", "url": "https://www.ensembl.org/id/ENSBTAP00000017467.4" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [], "orthologs": [ { "uniprot_canonical_ac": "A0A3L7IH46-1", "protein_name": "Actin-related protein T3", "gene_name": "Actrt3", "tax_id": 10029, "organism": "Cricetulus griseus", "sequence": { "sequence": "MSGYQPPVVIDNGSGMIKAGLAGTREPQFVYPNILGRTKGHKTAVNCGQELCVGDQAQERRSFLSISYPMDRGLISSWGDMEIMWKHIYDYNLNLKASDGPVLVTEPALNPMVDRQHISEVFFETLGVPAFYLSVQAVLALFAAGFTTGLVLNSGAGISQCVPVFEGYCLPHGVKQLNVAGLDLTHYLMMLLKEDGVMLLRTEDRKIVSDIKENACYVAMNYEDEMVKEPSLQKIYTLPDGKTIKLSNQVFRCPEALFSPWLVNVDAPGIDKMCLSSIMKCDTDLRNSFFSNIILAGGSTSFPGLDKRLIKDVAKMAPANTPVQVTAPPERKISVWMGGSILASLSAFQDMWITAAEFEEVGPNIVHQRCF", "length": 371 }, "evidence": [ { "id": "F6PXW3", "url": "https://omabrowser.org/oma/group/F6PXW3/", "database": "OMA" } ], "glygen_name": "Hamster", "common_name": "Chinese hamster" }, { "uniprot_canonical_ac": "D4ABA6-1", "protein_name": "Actin-related protein T3", "gene_name": "Actrt3", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MSSYQPPVVIDNGSGMIKAGLAGAREPQFVYPNILGRTKNHSPAADSKQELRVGDQAQERRSFLSISYPVERGLISSWGDMEIMWKHIYDYNLNLNPSDGPVLVTEPALNPLADRQHISEVFFENLGVPAFYMSVQAVLALFAAGFTTGLVLNSGAGITQCVPIFEGYCLSHGVKQLNVAGIDLTNYLMMLLKDDGIMLLRTGDRKTVTDIKENACYVAMNYDEEMVKESNVEKMYTLPDGKTVKLRKQVFRCPEALFSPYLVNVDAPGIDRICFSSIMKCDADLRNSFFSNIILSGGSTSFPGLDKRLIKDVAKLAPANTTVQVVAPPERKISVWMGGSILASLSAFQDMWITAAEFEEVGPNIVHQRCF", "length": 371 }, "evidence": [ { "id": "F6PXW3", "url": "https://omabrowser.org/oma/group/F6PXW3/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "Q8BXF8-1", "protein_name": "Actin-related protein T3", "gene_name": "Actrt3", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MSGYQPPVVIDNGSGMIKAGLAGTREPQFVYPNILGRSKGHTADSRQELCVGDQAQERRSFLSISYPVERGLISSWGDMEIMWKHIYDYNLNLNASDGPVLVTEPALNPLADRQHISEVFFENLGVPAFYMSAQAVLALFAAGFTTGLVLNSGAGITQCVPIFEGYCLSHGVKQLNVAGSDLTSYLMMLLKGDGIMLLRTGDRKVVTDIKENACYVAMNYEDEMTKDSNLEKIYTLPDGKTVKLHKQLFHCPEALFSPYLVNVDAPGIDKMCFGSIMKCDTDLRNSFFSNIILSGGSTSFPGLDKRLIKDVAKLAPANTAVQVIAPPERKISVWMGGSILASLSAFQDMWITAAEFEEVGPNIVHQRCF", "length": 369 }, "evidence": [ { "id": "F6PXW3", "url": "https://omabrowser.org/oma/group/F6PXW3/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q9BYD9-1", "protein_name": "Actin-related protein T3", "gene_name": "ACTRT3", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MNHCQLPVVIDNGSGMIKAGVAGCREPQFIYPNIIGRAKGQSRAAQGGLELCVGDQAQDWRSSLFISYPVERGLITSWEDMEIMWKHIYDYNLKLKPCDGPVLITEPALNPLANRQQITEMFFEHLGVPAFYMSIQAVLALFAAGFTTGLVLNSGAGVTQSVPIFEGYCLPHGVQQLDLAGLDLTNYLMVLMKNHGIMLLSASDRKIVEDIKESFCYVAMNYEEEMAKKPDCLEKVYQLPDGKVIQLHDQLFSCPEALFSPCHMNLEAPGIDKICFSSIMKCDTGLRNSFFSNIILAGGSTSFPGLDKRLVKDIAKVAPANTAVQVIAPPERKISVWMGGSILASLSAFQDMWITAAEFKEVGPNIVHQRCF", "length": 372 }, "evidence": [ { "id": "F6PXW3", "url": "https://omabrowser.org/oma/group/F6PXW3/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" } ], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 2, "go_terms": [ { "name": "cytoskeleton", "id": "GO:0005856", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005856", "evidence": [ { "database": "UniProtKB", "id": "F6PXW3", "url": "https://www.uniprot.org/uniprotkb/F6PXW3" } ], "pmid": "" }, { "name": "male germ cell nucleus", "id": "GO:0001673", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0001673", "evidence": [ { "database": "UniProtKB", "id": "F6PXW3", "url": "https://www.uniprot.org/uniprotkb/F6PXW3" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 83, "end_pos": 85, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [ { "pdb_id": "AF-F6PXW3-F1", "pdb_chain": "global", "start_pos": 1, "end_pos": 439, "overlap": "1.0", "method": "AlphaFold", "type": "alphafold", "resolution": -1.0, "url": "https://data.glygen.org/ln2downloads/pdb/current/AF-F6PXW3-F1.pdb", "url_external": "https://alphafold.ebi.ac.uk/entry/F6PXW3" } ], "lectin_list": [], "domain_list": [], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" }, { "name": "homologset.oma", "label": "OMA Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 83, "end_pos": 85 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ], "tool_support": { "graph_view": "yes" } }, { "uniprot_canonical_ac": "F6PV58-1", "uniprot_ac": "F6PV58", "uniprot_id": "F6PV58_BOVIN", "mass": { "chemical_mass": 71606.0, "monoisotopic_mass": 71606.0 }, "refseq": {}, "gene_names": [ { "name": "ZSCAN12", "type": "recommended", "evidence": [ { "id": "F6PV58", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F6PV58" } ] } ], "protein_names": [ { "name": "Zinc finger and SCAN domain-containing protein 12", "type": "recommended", "evidence": [ { "id": "F6PV58", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F6PV58/entry#names_and_taxonomy" } ] }, { "name": "Zinc finger protein 96", "type": "synonym", "evidence": [ { "id": "F6PV58", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F6PV58/entry#names_and_taxonomy" } ] } ], "function": [ { "annotation": "May be involved in transcriptional regulation.", "evidence": [ { "database": "UniProtKB", "id": "A0A3Q1MEV8", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1MEV8#function" }, { "database": "UniProtKB", "id": "ARBA00003767", "url": "https://www.uniprot.org/uniprotkb/ARBA00003767#function" }, { "database": "UniProtKB", "id": "F6PV58", "url": "https://www.uniprot.org/uniprotkb/F6PV58#function" }, { "database": "UniProtKB", "id": "A0AAA9TYP1", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TYP1#function" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Bos taurus", "taxid": 9913, "evidence": [ { "database": "UniProtKB", "id": "F6PV58", "url": "https://www.uniprot.org/uniprotkb/F6PV58" } ], "common_name": "Bovine", "glygen_name": "Bovine", "reference_species": "Bos taurus [9913]" } ], "gene": [ { "name": "ZSCAN12", "url": "https://www.uniprot.org/uniprotkb/F6PV58", "locus": { "chromosome": "23", "start_pos": 30356219, "end_pos": 30335852, "strand": "-", "evidence": [ { "database": "Ensembl Gene", "id": "ENSBTAG00000008943", "url": "https://www.ensembl.org/id/ENSBTAG00000008943" } ] } } ], "crossref": [ { "id": "F6PV58", "url": "https://alphafold.ebi.ac.uk/entry/F6PV58", "database": "AlphaFoldDB", "categories": [] }, { "id": "ENSBTAG00000008943", "url": "https://bgee.org/?page=gene&gene_id=ENSBTAG00000008943", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "cd07936", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd07936", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "768084", "url": "https://www.ncbi.nlm.nih.gov/gene/768084", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR003309", "url": "https://www.ebi.ac.uk/interpro/entry/IPR003309", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR013087", "url": "https://www.ebi.ac.uk/interpro/entry/IPR013087", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR036236", "url": "https://www.ebi.ac.uk/interpro/entry/IPR036236", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR038269", "url": "https://www.ebi.ac.uk/interpro/entry/IPR038269", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR050752", "url": "https://www.ebi.ac.uk/interpro/entry/IPR050752", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR050758", "url": "https://www.ebi.ac.uk/interpro/entry/IPR050758", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "CHQCKEC", "url": "https://omabrowser.org/oma/group/CHQCKEC/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "A0A3Q1MEV8", "url": "https://www.orthodb.org/?gene=A0A3Q1MEV8", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "F6PV58", "url": "https://www.orthodb.org/?gene=F6PV58", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR23234", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR23234", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR23234:SF10", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR23234:SF10", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR24384", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR24384", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR24384:SF246", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR24384:SF246", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR24390", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR24390", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR24390:SF159", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR24390:SF159", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00096", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00096", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF02023", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF02023", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "A0A3Q1MEV8", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1MEV8", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A3Q1MEV8-1", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1MEV8-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0AAA9TYP1", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TYP1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0AAA9TYP1-1", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TYP1-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "F6PV58", "url": "https://www.uniprot.org/uniprotkb/F6PV58", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "F6PV58-1", "url": "https://www.uniprot.org/uniprotkb/F6PV58-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MMAYTWSIQAMKDREELLEVKIEEEELEEEHKYATTQDQNLQKNTTHSREVFRRYFRQFCYQETSGPREALSRLRELCHQWLKPETHTKEQILELLVLEQFLTILPEELQAWVQEQHPESGEEVVTVLEDLERELDEPGYQVSVRSEEQELQEIVPLRTEQEPRICLQSVQAQPKCESAELEAQQKQDIETGNEYRNLKQEVSPEMKPYGNIASKFENEMSQPARYEKTYEPEEKTGESSEYSREDKEPTCDENGVSLTENLDLSEHQRICPGEKPYVCDVCGRAFSQHSRFVEHQRIHTGDRPYKCKECGKTFRGRTVLIRHKIIHTGEKLYKCNECGKAFAQWSALNQHQRLHTGEKHYHCNECGKAFSQKAGLFHHLKIHTRDKPYHCTQCNKSFSRRSILTQHQGVHTGAKPYECSECGKAFVYNSSLVSHQEIHHKEKCYQCKECGKSFSQSGLTQHQRIHNGEKPYKCDVCGKAFIQRTSLIEHQRIHTGERPYQCDKCGKAFTQRSVLKEHQKVHTGERPYKCNECGNAFRGITSLIQHQRIHTGEKPYQCDECGKAFRQRSDLSKHQRIHNRGDPYTCKVRGESFTQNSALIQHQTTHKAEKSGSV", "length": 614, "header": "tr|F6PV58-1|F6PV58_BOVIN Isoform 1 of Zinc finger and SCAN domain-containing protein 12 OS=Bos taurus OX=9913 GN=ZSCAN12 PE=3 SV=1 CANONICAL=F6PV58-1" }, "isoforms": [ { "isoform_ac": "A0A3Q1MEV8-1", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1MEV8/entry", "sequence": { "sequence": "MMAYTWSIQAMKDREELLEVKIEEEELEEEHKYATTQDQNLQKNTTHSREVFRRYFRQFCYQETSGPREALSRLRELCHQWLKPETHTKEQILELLVLEQFLTILPEELQAWVQEQHPESGEEVVTVLEDLERELDEPGYQVSVRSEEQELQEIVPLRTEQEPRICLQSVQAQPKCESAELEAQQKQDIETGNEYRNLKQEVSPEMKPYGNIASKFENEMSQPARYEKTYEPEEKTGESSEYSREDKEPTCDENGVSLTENLDLSEHQRICPGEKPYVCDVCGRAFSQHSRFVEHQRIHTGDRPYKCKECGKTFRGRTVLIRHKIIHTGEKLYKCNECGKAFAQWSALNQHQRLHTGEKHYHCNECGKAFSQKAGLFHHLKIHTRDKPYHCTQCNKSFSRRSILTQHQGVHTGAKPYECSECGKAFVYNSSLVSHQEIHHKEKCYQCKECGKSFSQSGLTQHQRIHNGEKPYKCDVCGKAFIQRTSLIEHQRIHTGERPYQCDKCGKAFTQRSVLKEHQKVHTGERPYKCNECGNAFRGITSLIQHQRIHTGEKPYQCDECGKAFRQSLNIWKFTVHILLTPGCILSPCLFNLYA", "length": 595, "header": "tr|A0A3Q1MEV8-1|F6PV58_BOVIN Computationally mapped isoform of Zinc finger and SCAN domain-containing protein 12 OS=Bos taurus OX=9913 GN=ZSCAN12 PE=3 SV=2 CANONICAL=F6PV58-1" }, "locus": { "chromosome": "23", "start_pos": 30348757, "end_pos": 30336776, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000067580.3", "url": "https://www.ensembl.org/id/ENSBTAT00000067580.3" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000067431.2", "url": "https://www.ensembl.org/id/ENSBTAP00000067431.2" } ] } }, { "isoform_ac": "A0AAA9TYP1-1", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TYP1/entry", "sequence": { "sequence": "MMAYTWSIQAMKDREELLEVKIEEEELEEEHKYATTQDQNLQKNTTHSREVFRRYFRQFCYQETSGPREALSRLRELCHQWLKPETHTKEQILELLVLEQFLTILPEELQAWVQEQHPESGEEVVTVLEDLERELDEPGYQVSVRSEEQELQEIVPLRTEQEPRICLQSVQAQPKCESAELEAQQKQDIETGNEYRNLKQEVSPEMKPYGNIASKFENEMSQPARYEKTYEPEEKTGESSEYSREDKEPTCDENGVSLTENLDLSEHQRICPGEKPYVCDVCGRAFSQHSRFVEHQRIHTGDRPYKCKECGKTFRGRTVLIRHKIIHTGEKLYKCNECGKAFAQWSALNQHQRLHTGEKHYHCNECGKAFSQKAGLFHHLKIHTRDKPYHCTQCNKSFSRRSILTQHQGVHTGAKPYECSECGKAFVYNSSLVSHQEIHHKEKCYQCKECGKSFSQSGLTQHQRIHNGEKPYKCDVCGKAFIQRTSLIEHQRIHTGERPYQCDKCGKAFTQRSVLKEHQKVHTGERPYKCNECGNAFRGITSLIQHQRIHTGEKPYQCDECGKAFRQRKKTSYKEILLKNQCEPQAGVNLLLSSLIPEWQSSCRKDLY", "length": 608, "header": "tr|A0AAA9TYP1-1|A0AAA9TYP1_BOVIN Computationally mapped isoform of Zinc finger and SCAN domain-containing protein 12 OS=Bos taurus OX=9913 GN=ZSCAN12 PE=3 SV=1 CANONICAL=F6PV58-1" }, "locus": { "chromosome": "23", "start_pos": 30355443, "end_pos": 30336776, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000105526.2", "url": "https://www.ensembl.org/id/ENSBTAT00000105526.2" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000102355.1", "url": "https://www.ensembl.org/id/ENSBTAP00000102355.1" } ] } }, { "isoform_ac": "F6PV58-1", "url": "https://www.uniprot.org/uniprotkb/F6PV58/entry", "sequence": { "sequence": "MMAYTWSIQAMKDREELLEVKIEEEELEEEHKYATTQDQNLQKNTTHSREVFRRYFRQFCYQETSGPREALSRLRELCHQWLKPETHTKEQILELLVLEQFLTILPEELQAWVQEQHPESGEEVVTVLEDLERELDEPGYQVSVRSEEQELQEIVPLRTEQEPRICLQSVQAQPKCESAELEAQQKQDIETGNEYRNLKQEVSPEMKPYGNIASKFENEMSQPARYEKTYEPEEKTGESSEYSREDKEPTCDENGVSLTENLDLSEHQRICPGEKPYVCDVCGRAFSQHSRFVEHQRIHTGDRPYKCKECGKTFRGRTVLIRHKIIHTGEKLYKCNECGKAFAQWSALNQHQRLHTGEKHYHCNECGKAFSQKAGLFHHLKIHTRDKPYHCTQCNKSFSRRSILTQHQGVHTGAKPYECSECGKAFVYNSSLVSHQEIHHKEKCYQCKECGKSFSQSGLTQHQRIHNGEKPYKCDVCGKAFIQRTSLIEHQRIHTGERPYQCDKCGKAFTQRSVLKEHQKVHTGERPYKCNECGNAFRGITSLIQHQRIHTGEKPYQCDECGKAFRQRSDLSKHQRIHNRGDPYTCKVRGESFTQNSALIQHQTTHKAEKSGSV", "length": 614, "header": "tr|F6PV58-1|F6PV58_BOVIN Isoform 1 of Zinc finger and SCAN domain-containing protein 12 OS=Bos taurus OX=9913 GN=ZSCAN12 PE=3 SV=1 CANONICAL=F6PV58-1" }, "locus": { "chromosome": "23", "start_pos": 30346116, "end_pos": 30336776, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000011774.6", "url": "https://www.ensembl.org/id/ENSBTAT00000011774.6" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000011774.5", "url": "https://www.ensembl.org/id/ENSBTAP00000011774.5" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [], "orthologs": [ { "uniprot_canonical_ac": "A0A0G2K4Z9-1", "protein_name": "Large ribosomal subunit protein eL8", "gene_name": "Zscan12", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MPKGKKAKGKKVAPASAVVKKQEAKKVVNPLFEKRPKNFGIGQDIQPKRDLKWPCYIRLQQQRAILYKRLKVPPAINQFTQALDRQTATQLLKLAHKYRPETKQEKKQRLLARAEKKAAGKRDVPPKRVPVLQAGVNTVTTLVENKKAQLVMIAHDVDPIELVVFLPALCRKMGVPYCIIKGKDRLGRLVHRKTCTTVAFTQVNSEDKGALAKLVEAIRANYNDRYAMMASTNDTKICKNQDGLLEIKMEEECKYTTRQVRNLQKNTYNRDVFRKYFRQFCYQETSGPREALSRLRELCHQWLRPDMHSKEQILELLVLEQFLTILPEELQAWVQEQNPESVEEVVTVLEDLERELDELGYRTSVQIEKQEMLLRETKPLAAEQKPSVSLQFVKAKPGCELADGEAQEEQVSGIETGNESRNVTLKQGLWEGMEAEQNPSSRLAKDTLKCEETRDPREESSGISREDSQPLRNENVVNLTENSNHAELQNICPGRKVHGCDECGKTFSQHSRLIEHRRIHTGDRPYRCEECGKTFRWRTVLIRHKVVHTGEKPYKCNECGRAFGQWSALNQHQRLHSGEKHYHCNECGKAFCQKAGLFHHLKSHRRNRPYQCLQCNKSFNRRSTLSQHQGVHTGTKPYECSDCGRAFVYNSSLATHQETHHKEKLFTQSGPSQQRKNHTSEKSYKCSICGKTFVQKTSLIEHEQIHTEERPYKCAEGGKAFIQVSDLTEH", "length": 730 }, "evidence": [ { "id": "F6PV58", "url": "https://omabrowser.org/oma/group/F6PV58/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "O43309-1", "protein_name": "Zinc finger and SCAN domain-containing protein 12", "gene_name": "ZSCAN12", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MASTWAIQAHMDQDEPLEVKIEEEKYTTRQDWDLRKNNTHSREVFRQYFRQFCYQETSGPREALSRLRELCHQWLRPETHTKEQILELLVLEQFLTILPEELQAWVQEQHPESGEEVVTVLEDLERELDEPGEQVSVHTGEQEMFLQETVRLRKEGEPSMSLQSMKAQPKYESPELESQQEQVLDVETGNEYGNLKQEVSEEMEPHGKTSSKFENDMSKSARCGETREPEEITEEPSACSREDKQPTCDENGVSLTENSDHTEHQRICPGEESYGCDDCGKAFSQHSHLIEHQRIHTGDRPYKCEECGKAFRGRTVLIRHKIIHTGEKPYKCNECGKAFGRWSALNQHQRLHTGEKHYHCNDCGKAFSQKAGLFHHIKIHTRDKPYQCTQCNKSFSRRSILTQHQGVHTGAKPYECNECGKAFVYNSSLVSHQEIHHKEKCYQCKECGKSFSQSGLIQHQRIHTGEKPYKCDVCEKAFIQRTSLTEHQRIHTGERPYKCDKCGKAFTQRSVLTEHQRIHTGERPYKCDECGNAFRGITSLIQHQRIHTGEKPYQCDECGKAFRQRSDLSKHQRIHNRRGTYVCKECGKSFRQNSALTQHQTIHKGEKSVSV", "length": 611 }, "evidence": [ { "id": "F6PV58", "url": "https://omabrowser.org/oma/group/F6PV58/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "Q9Z1D7-1", "protein_name": "Zinc finger and SCAN domain-containing protein 12", "gene_name": "Zscan12", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MTSTSDTKVCKNQGGLLEIKMEEECKYTTRQDRNLQKNTYNRDVFRKYFRQFCYQETSGPREALSRLRELCRQWLRPDLNSKEQILELLVLEQFLTILPGELQAWVQEQNPESVEEVVTVLEDLERELDELGYRASVQTEEQVTFQEVKPLATEQKPSVSLQFVKAKPGCELAGREAQEEQVSGVETGNEPRNVTLKQGLWEGTEAEQNPASRLAKDALECEEAHNPGEESSGISHEDSQPLRNENGVNSPANSEYAKHQSICPGRKVHGCDECGKSFTQHSRLIEHKRVHTGDRPYKCEVCGKTFRWRTVLIRHKVVHTGEKPYKCNECGRAFGQWSALNQHQRLHSGEKHYHCNECGKAFCQKAGLFHHLKSHRRNRPYQCLQCNKSFNRRSTLSQHQGVHTGAKPYECNDCGKAFVYNSSLATHQETHHKEKPFTQSGPIQQQRNHTKEKPYKCSVCGKAFIQKISLIEHEQIHTGERPYKCAEGGKAFIQMSELTEH", "length": 501 }, "evidence": [ { "id": "F6PV58", "url": "https://omabrowser.org/oma/group/F6PV58/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" } ], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 2, "go_terms": [ { "name": "nuclear lumen", "id": "GO:0031981", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0031981", "evidence": [ { "database": "UniProtKB", "id": "F6PV58", "url": "https://www.uniprot.org/uniprotkb/F6PV58" } ], "pmid": "" }, { "name": "nucleus", "id": "GO:0005634", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005634", "evidence": [ { "database": "UniProtKB", "id": "F6PV58", "url": "https://www.uniprot.org/uniprotkb/F6PV58" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 2, "go_terms": [ { "name": "DNA-templated transcription", "id": "GO:0006351", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006351", "evidence": [ { "database": "UniProtKB", "id": "F6PV58", "url": "https://www.uniprot.org/uniprotkb/F6PV58" } ], "pmid": "" }, { "name": "regulation of transcription by RNA polymerase II", "id": "GO:0006357", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006357", "evidence": [ { "database": "UniProtKB", "id": "F6PV58", "url": "https://www.uniprot.org/uniprotkb/F6PV58" } ], "pmid": "" } ] }, { "name": "Molecular Function", "total": 4, "go_terms": [ { "name": "zinc ion binding", "id": "GO:0008270", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008270", "evidence": [ { "database": "UniProtKB", "id": "F6PV58", "url": "https://www.uniprot.org/uniprotkb/F6PV58" } ], "pmid": "" }, { "name": "RNA polymerase II cis-regulatory region sequence-specific DNA binding", "id": "GO:0000978", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000978", "evidence": [ { "database": "UniProtKB", "id": "F6PV58", "url": "https://www.uniprot.org/uniprotkb/F6PV58" } ], "pmid": "" }, { "name": "DNA-binding transcription factor activity, RNA polymerase II-specific", "id": "GO:0000981", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000981", "evidence": [ { "database": "UniProtKB", "id": "F6PV58", "url": "https://www.uniprot.org/uniprotkb/F6PV58" } ], "pmid": "" }, { "name": "DNA binding", "id": "GO:0003677", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003677", "evidence": [ { "database": "UniProtKB", "id": "F6PV58", "url": "https://www.uniprot.org/uniprotkb/F6PV58" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 395, "end_pos": 397, "annotation": "n_glycosylation_sequon" }, { "start_pos": 429, "end_pos": 431, "annotation": "n_glycosylation_sequon" }, { "start_pos": 44, "end_pos": 46, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [ { "pdb_id": "AF-F6PV58-F1", "pdb_chain": "global", "start_pos": 1, "end_pos": 614, "overlap": "1.0", "method": "AlphaFold", "type": "alphafold", "resolution": -1.0, "url": "https://data.glygen.org/ln2downloads/pdb/current/AF-F6PV58-F1.pdb", "url_external": "https://alphafold.ebi.ac.uk/entry/F6PV58" } ], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "F6PV58", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F6PV58" }, { "id": "PS50157", "database": "PROSITE", "url": "https://prosite.expasy.org/PS50157" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "C2H2-type", "eco_id": "ECO_0000259", "start_pos": 277, "end_pos": 304, "start_aa": "Tyr", "end_aa": "Pro", "glycosite_overlap": [] }, { "evidence": [ { "id": "F6PV58", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F6PV58" }, { "id": "PS50804", "database": "PROSITE", "url": "https://prosite.expasy.org/PS50804" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "SCAN box", "eco_id": "ECO_0000259", "start_pos": 53, "end_pos": 135, "start_aa": "Arg", "end_aa": "Leu", "glycosite_overlap": [] } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" }, { "name": "homologset.oma", "label": "OMA Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 395, "end_pos": 397 }, { "start_pos": 429, "end_pos": 431 }, { "start_pos": 44, "end_pos": 46 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ], "tool_support": { "graph_view": "yes" } }, { "uniprot_canonical_ac": "F1N2T0-1", "uniprot_ac": "F1N2T0", "uniprot_id": "F1N2T0_BOVIN", "mass": { "chemical_mass": 46432.0, "monoisotopic_mass": 46432.0 }, "refseq": { "ac": "XP_005208229", "name": "heterogeneous nuclear ribonucleoprotein D-like isoform X1", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_005208229" }, "gene_names": [ { "name": "HNRNPDL", "type": "recommended", "evidence": [ { "id": "F1N2T0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1N2T0" } ] }, { "name": "HNRNPDL", "type": "synonym", "evidence": [ { "id": "XP_005208229", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_005208229" } ] }, { "name": "HNRPDL", "type": "synonym", "evidence": [ { "id": "XP_005208229", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_005208229" } ] } ], "protein_names": [ { "name": "Heterogeneous nuclear ribonucleoprotein D-like", "type": "recommended", "evidence": [ { "id": "F1N2T0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1N2T0/entry#names_and_taxonomy" } ] }, { "name": "heterogeneous nuclear ribonucleoprotein D-like isoform X1", "type": "synonym", "evidence": [ { "id": "XP_005208229", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_005208229" } ] } ], "function": [ { "annotation": "Acts as a transcriptional regulator. Promotes transcription repression. Promotes transcription activation in differentiated myotubes. Binds to double- and single-stranded DNA sequences. Binds to the transcription suppressor CATR sequence of the COX5B promoter. Binds with high affinity to RNA molecules that contain AU-rich elements (AREs) found within the 3'-UTR of many proto-oncogenes and cytokine mRNAs. Binds both to nuclear and cytoplasmic poly(A) mRNAs. Binds to poly(G) and poly(A), but not to poly(U) or poly(C) RNA homopolymers. Binds to the 5'-ACUAGC-3' RNA consensus sequence.", "evidence": [ { "database": "UniProtKB", "id": "A0A3Q1NLI5", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1NLI5#function" }, { "database": "UniProtKB", "id": "ARBA00056332", "url": "https://www.uniprot.org/uniprotkb/ARBA00056332#function" }, { "database": "UniProtKB", "id": "F1N2T0", "url": "https://www.uniprot.org/uniprotkb/F1N2T0#function" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Bos taurus", "taxid": 9913, "evidence": [ { "database": "UniProtKB", "id": "F1N2T0", "url": "https://www.uniprot.org/uniprotkb/F1N2T0" } ], "common_name": "Bovine", "glygen_name": "Bovine", "reference_species": "Bos taurus [9913]" } ], "gene": [ { "name": "HNRNPDL", "url": "https://www.uniprot.org/uniprotkb/F1N2T0", "locus": { "chromosome": "6", "start_pos": 97209944, "end_pos": 97216516, "strand": "+", "evidence": [ { "database": "Ensembl Gene", "id": "ENSBTAG00000014804", "url": "https://www.ensembl.org/id/ENSBTAG00000014804" } ] } } ], "crossref": [ { "id": "F1N2T0", "url": "https://alphafold.ebi.ac.uk/entry/F1N2T0", "database": "AlphaFoldDB", "categories": [] }, { "id": "ENSBTAG00000014804", "url": "https://bgee.org/?page=gene&gene_id=ENSBTAG00000014804", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "cd12585", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd12585", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "cd12758", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd12758", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "534770", "url": "https://www.ncbi.nlm.nih.gov/gene/534770", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR000504", "url": "https://www.ebi.ac.uk/interpro/entry/IPR000504", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR012677", "url": "https://www.ebi.ac.uk/interpro/entry/IPR012677", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR034847", "url": "https://www.ebi.ac.uk/interpro/entry/IPR034847", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR035979", "url": "https://www.ebi.ac.uk/interpro/entry/IPR035979", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "QVDTEMN", "url": "https://omabrowser.org/oma/group/QVDTEMN/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "A0A3Q1NLI5", "url": "https://www.orthodb.org/?gene=A0A3Q1NLI5", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "F1N2T0", "url": "https://www.orthodb.org/?gene=F1N2T0", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR48033", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR48033", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR48033:SF2", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR48033:SF2", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00076", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00076", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "XP_005208229", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_005208229", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A3Q1MEX4", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1MEX4", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A3Q1MEX4-1", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1MEX4-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A3Q1NLI5", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1NLI5", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A3Q1NLI5-1", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1NLI5-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0AAA9S167", "url": "https://www.uniprot.org/uniprotkb/A0AAA9S167", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0AAA9S167-1", "url": "https://www.uniprot.org/uniprotkb/A0AAA9S167-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "F1N2T0", "url": "https://www.uniprot.org/uniprotkb/F1N2T0", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "F1N2T0-1", "url": "https://www.uniprot.org/uniprotkb/F1N2T0-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MEVPPRLSHVPPPLFPSAPATLASRSLSHWRPRPPRQLAPLLPSLAPSSARQGARRAQRHVTAQQPSRLAGGAAIKGGRRRRPDLFRRHFKSSSIQRSAAAAAATRSARQHLPADHSAAMEDMNEYSNIEEFAEGSKINASKNQQDDGKMFIGGLSWDTSKKDLTEYLSRFGEVVDCTIKTDPVTGRSRGFGFVLFKDAASVDKVLELKEHKLDGKLIDPKRAKALKGKEPPKKVFVGGLSPDTSEEQIKEYFGAFGEIENIELPMDTKTNERRGFCFITYTDEEPVKKLLESRYHQIGSGKCEIKVAQPKEVYRQQQQQQKGGRGAAAGGRGGTRGRGRGQGQNWNQGFNNYYDQGYGNYNSAYGGDQNYSGYGGYDYTGYNYGNYGYGQGYADYSGQQSTYGKASRGGGNHQNNYQPY", "length": 420, "header": "tr|F1N2T0-1|F1N2T0_BOVIN Isoform 1 of Heterogeneous nuclear ribonucleoprotein D-like OS=Bos taurus OX=9913 GN=HNRNPDL PE=4 SV=1 CANONICAL=F1N2T0-1" }, "isoforms": [ { "isoform_ac": "A0A3Q1MEX4-1", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1MEX4/entry", "sequence": { "sequence": "MEVPPRLSHVPPPLFPSAPATLASRSLSHWRPRPPRQLAPLLPSLAPSSARQGARRAQRHVTAQQPSRLAGGAAIKGGRRRRPDLFRRHFKSSSIQRSAAAAAATRSARQHLPADHSAAMEDMNEYSNIEEFAEGSKINASKNQQDDGKMFIGGLSWDTSKKDLTEYLSRFGEVVDCTIKTDPVTGRSRGFGFVLFKDAASVDKVLELKEHKLDGKLIDPKRAKALKGKEPPKKVFVGGLSPDTSEEQIKEYFGAFGEIENIELPMDTKTNERRGFCFITYTDEEPVKKLLESRYHQIGSGKVRAKTGTKDLITIMIKDMEITIVPMVVIKTIVAMAAMIILGITMGTMDMDRDMQTTVANRALTARHPEGVAITKTITSRIKGDTAENSGNFIAGRVSP", "length": 400, "header": "tr|A0A3Q1MEX4-1|F1N2T0_BOVIN Computationally mapped isoform of Heterogeneous nuclear ribonucleoprotein D-like OS=Bos taurus OX=9913 GN=HNRNPDL PE=4 SV=1 CANONICAL=F1N2T0-1" }, "locus": { "chromosome": "6", "start_pos": 97216246, "end_pos": 97212180, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000082552.2", "url": "https://www.ensembl.org/id/ENSBTAT00000082552.2" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000072716.2", "url": "https://www.ensembl.org/id/ENSBTAP00000072716.2" } ] } }, { "isoform_ac": "A0A3Q1NLI5-1", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1NLI5/entry", "sequence": { "sequence": "MEVPPRLSHVPPPLFPSAPATLASRSLSHWRPRPPRQLAPLLPSLAPSSARQGARRAQRHVTAQQPSRLAGGAAIKGGRRRRPDLFRRHFKSSSIQRSAAAAAATRSARQHLPADHSAAMEDMNEYSNIEEFAEGSKINASKNQQDDGKMFIGGLSWDTSKKDLTEYLSRFGEVVDCTIKTDPVTGRSRGFGFVLFKDAASVDKVLELKEHKLDGKLIDPKRAKALKGKEPPKKVFVGGLSPDTSEEQIKEYFGAFGEIENIELPMDTKTNERRGFCFITYTDEEPVKKLLESRYHQIGSGKCEIKVAQPKEVYRQQQQQQKGGRGAAAGGRGGTRGRGRGQQSTYGKASRGGGNHQNNYQPY", "length": 363, "header": "tr|A0A3Q1NLI5-1|F1N2T0_BOVIN Computationally mapped isoform of Heterogeneous nuclear ribonucleoprotein D-like OS=Bos taurus OX=9913 GN=HNRNPDL PE=4 SV=2 CANONICAL=F1N2T0-1" }, "locus": { "chromosome": "6", "start_pos": 97216246, "end_pos": 97212606, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000072334.2", "url": "https://www.ensembl.org/id/ENSBTAT00000072334.2" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000073278.2", "url": "https://www.ensembl.org/id/ENSBTAP00000073278.2" } ] } }, { "isoform_ac": "A0AAA9S167-1", "url": "https://www.uniprot.org/uniprotkb/A0AAA9S167/entry", "sequence": { "sequence": "MEVPPRLSHVPPPLFPSAPATLASRSLSHWRPRPPRQLAPLLPSLAPSSARQGARRAQRHVTAQQPSRLAGGAAIKGGRRRRPDLFRRHFKSSSIQRSAAAAAATRSARQHLPADHSAAMEDMNEYSNIEEFAEGSKINASKNQQDDGKMFIGGLSWDTSKKDLTEYLSRFGEVVDCTIKTDPVTGRSRGFGFVLFKDAASVDKVLELKEHKLDGKLIDPKRAKALKGKEPPKKVFVGGLSPDTSEEQIKEYFGAFGEIENIELPMDTKTNERRGFCFITYTDEEPVKKLLESRYHQIGSGKVRAKTGTKDLITIMIKDMEITIVPMVVIKTIVAMAAMIILGITMGTMDMDRDMQTTVANRALTARHPEGVAITKTITSRIKGDTAENRKRLLK", "length": 395, "header": "tr|A0AAA9S167-1|F1N2T0_BOVIN Computationally mapped isoform of Heterogeneous nuclear ribonucleoprotein D-like OS=Bos taurus OX=9913 GN=HNRNPDL PE=4 SV=1 CANONICAL=F1N2T0-1" }, "locus": { "chromosome": "6", "start_pos": 97216246, "end_pos": 97211404, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000118411.1", "url": "https://www.ensembl.org/id/ENSBTAT00000118411.1" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000078721.1", "url": "https://www.ensembl.org/id/ENSBTAP00000078721.1" } ] } }, { "isoform_ac": "F1N2T0-1", "url": "https://www.uniprot.org/uniprotkb/F1N2T0/entry", "sequence": { "sequence": "MEVPPRLSHVPPPLFPSAPATLASRSLSHWRPRPPRQLAPLLPSLAPSSARQGARRAQRHVTAQQPSRLAGGAAIKGGRRRRPDLFRRHFKSSSIQRSAAAAAATRSARQHLPADHSAAMEDMNEYSNIEEFAEGSKINASKNQQDDGKMFIGGLSWDTSKKDLTEYLSRFGEVVDCTIKTDPVTGRSRGFGFVLFKDAASVDKVLELKEHKLDGKLIDPKRAKALKGKEPPKKVFVGGLSPDTSEEQIKEYFGAFGEIENIELPMDTKTNERRGFCFITYTDEEPVKKLLESRYHQIGSGKCEIKVAQPKEVYRQQQQQQKGGRGAAAGGRGGTRGRGRGQGQNWNQGFNNYYDQGYGNYNSAYGGDQNYSGYGGYDYTGYNYGNYGYGQGYADYSGQQSTYGKASRGGGNHQNNYQPY", "length": 420, "header": "tr|F1N2T0-1|F1N2T0_BOVIN Isoform 1 of Heterogeneous nuclear ribonucleoprotein D-like OS=Bos taurus OX=9913 GN=HNRNPDL PE=4 SV=1 CANONICAL=F1N2T0-1" }, "locus": { "chromosome": "6", "start_pos": 97216246, "end_pos": 97212606, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000019699.6", "url": "https://www.ensembl.org/id/ENSBTAT00000019699.6" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000019699.4", "url": "https://www.ensembl.org/id/ENSBTAP00000019699.4" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [], "orthologs": [ { "uniprot_canonical_ac": "A0A286ZYE7-1", "protein_name": "Heterogeneous nuclear ribonucleoprotein D-like", "gene_name": "HNRNPDL", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MEVPPRLSQVPPPLFPSAPATLASRSLSHWRPRAPRQLAPLLPSLAPSSARQGARRAQRHVTAQQPSRLAGVAAIKGGRRRRPDLFRRHFKSSSIQRSAAAAAATRTARPHPPADNPAAMEDMNEYSNIEEFAEGSKINASKNQQDDGKMFIGGLSWDTSKKDLTEYLSRFGEVVDCTIKTDPVTGRSRGFGFVLFKDAASVDKVLELKEHKLDGKLIDPKRAKALKGKEPPKKVFVGGLSPDTSEEQIKEYFGAFGEIENIELPMDTKTNERRGFCFITYTDEEPVKKLLESRYHQIGSGKCEIKVAQPKEVYRQQQQQQKGGRGAAAGGRGGTRGRGRGQGQNWNQGFNNYYDQGYGNYNSAYGGDQNYSGYGGYDYTGYNYGNYGYGQGYADYSGQQSTYGKASRGGGNHQNNYQPY", "length": 420 }, "evidence": [ { "id": "F1N2T0", "url": "https://omabrowser.org/oma/group/F1N2T0/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "O14979-1", "protein_name": "Heterogeneous nuclear ribonucleoprotein D-like", "gene_name": "HNRNPDL", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MEVPPRLSHVPPPLFPSAPATLASRSLSHWRPRPPRQLAPLLPSLAPSSARQGARRAQRHVTAQQPSRLAGGAAIKGGRRRRPDLFRRHFKSSSIQRSAAAAAATRTARQHPPADSSVTMEDMNEYSNIEEFAEGSKINASKNQQDDGKMFIGGLSWDTSKKDLTEYLSRFGEVVDCTIKTDPVTGRSRGFGFVLFKDAASVDKVLELKEHKLDGKLIDPKRAKALKGKEPPKKVFVGGLSPDTSEEQIKEYFGAFGEIENIELPMDTKTNERRGFCFITYTDEEPVKKLLESRYHQIGSGKCEIKVAQPKEVYRQQQQQQKGGRGAAAGGRGGTRGRGRGQGQNWNQGFNNYYDQGYGNYNSAYGGDQNYSGYGGYDYTGYNYGNYGYGQGYADYSGQQSTYGKASRGGGNHQNNYQPY", "length": 420 }, "evidence": [ { "id": "F1N2T0", "url": "https://omabrowser.org/oma/group/F1N2T0/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "Q08473-1", "protein_name": "RNA-binding protein squid", "gene_name": "sqd", "tax_id": 7227, "organism": "Drosophila melanogaster", "sequence": { "sequence": "MAENKQVDTEINGEDFTKDVTADGPGSENGDAGAAGSTNGSSDNQSAASGQRDDDRKLFVGGLSWETTEKELRDHFGKYGEIESINVKTDPQTGRSRGFAFIVFTNTEAIDKVSAADEHIINSKKVDPKKAKARHGKIFVGGLTTEISDEEIKTYFGQFGNIVEVEMPFDKQKSQRKGFCFITFDSEQVVTDLLKTPKQKIAGKEVDVKRATPKPENQMMGGMRGGPRGGMRGGRGGYGGRGGYNNQWDGQGSYGGYGGGYGGYGAGGYGDYYAGGYYNGYDYGYDGYGYGGGFEGNGYGGGGGGNMGGGRGGPRGGGGPKGGGGFNGGKQRGGGGRQQRHQPY", "length": 344 }, "evidence": [ { "id": "F1N2T0", "url": "https://omabrowser.org/oma/group/F1N2T0/", "database": "OMA" } ], "glygen_name": "Fruit fly", "common_name": "Fruit fly" }, { "uniprot_canonical_ac": "Q3SWU3-1", "protein_name": "Heterogeneous nuclear ribonucleoprotein D-like", "gene_name": "Hnrnpdl", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MTGTARSALPLPQSPARALRPSGAARAAPSLSPSRFSACPLDPSSFPTSGNKMFIGGLSWDTSKKDLTEYLSRFGEVVDCTIKTDPVTGRSRGFGFVLFKDAASVDKVLELKEHKLDGKLIDPKRAKALKGKEPPKKVFVGGLSPDTSEEQIKEYFGAFGEIENIELPMDTKTNERRGFCFITYTDEEPVKKLLESRYHQIGSGKCEIKVAQPKEVYRQQQQQQKGGRGAAAGGRGGARGRGRGQGQNWNQGFNNYYDQGYGNYNSAYGDESYSGYGGYDYTGYNYGSYGYGQGYTDYSGQQSTYGKASRGGGNHQNNYQPY", "length": 322 }, "evidence": [ { "id": "F1N2T0", "url": "https://omabrowser.org/oma/group/F1N2T0/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "Q5ZI72-1", "protein_name": "Heterogeneous nuclear ribonucleoprotein D-like", "gene_name": "HNRNPDL", "tax_id": 9031, "organism": "Gallus gallus", "sequence": { "sequence": "MEDATEMSGGAEEFAEGSKINASKNQQDDGKMFIGGLSWDTSKKDLTEYLSRFGEVVDCTIKTDPVTGRSRGFGFVLFKDAASVEKVLELKEHKLDGKLIDPKRAKALKGKEPPKKVFVGGLSPDTSEEQIKEYFGAFGEIENIELPMDTKTNERRGFCFITYTDEEPVKKLLESRYHQIGSGKCEIKVAQPKEVYRQQQQQQKGGKSNASGGRGGGRGRGRGQGQNWNQGFNNYYDQGYGNYNSAYSDQSYSGYGGYDYSGYNYPNYGYGPGYTDYSGQQSTYGKASRGGGNHQNNYQPY", "length": 301 }, "evidence": [ { "id": "F1N2T0", "url": "https://omabrowser.org/oma/group/F1N2T0/", "database": "OMA" } ], "glygen_name": "Chicken", "common_name": "Chicken" }, { "uniprot_canonical_ac": "Q75K16-1", "protein_name": "RNA-binding region RNP-1 domain-containing protein", "gene_name": "", "tax_id": 44689, "organism": "Dictyostelium discoideum", "sequence": { "sequence": "MAKDQKAIESKKRKKEESESETESSEENNASSSSESESEDELKVVGEGSSSSKSTFTKKESAAKDESSNTKTDDDLKVFVGQLPSGVTEYDLKEYFSECGDISNIKILNSNPQRVAAFITFADEKGRDTAITYNGKDFNGQGSLRINGANSKPSDGEGEPTTIVCRNIAFTVDETLVKEFFSKCGSISRVSLPVYEDSGRLKGFAFVSFDSEDAVEKAIALTGTKFEGREIQVERSQRGGGRSSSFGRGGGRGGFGGGRGGRGGFGNGGGRGGFGGGRGGGRGGSGGRGGFGNKRGRFE", "length": 299 }, "evidence": [ { "id": "F1N2T0", "url": "https://omabrowser.org/oma/group/F1N2T0/", "database": "OMA" } ], "glygen_name": "Cellular slime mold", "common_name": "Social amoeba" }, { "uniprot_canonical_ac": "Q9LHL2-1", "protein_name": "RNA-binding (RRM/RBD/RNP motifs) family protein", "gene_name": "RBGD3", "tax_id": 3702, "organism": "Arabidopsis thaliana", "sequence": { "sequence": "MGSRSRNDNFQSGDGASPGKIFIGGLHKDTTNTVFNKHFGKYGEITDSVIMRDRHTGQPRGFGFITFADPSVVDKVIEDTHVINGKQVEIKRTIPKGAGGNQSKDIKTKKIFVGGIPSTVTEDELKDFFAKYGNVVEHQVIRDHETNRSRGFGFVIFDSEEVVDELLSKGNMIDMADTQVEIKKAEPKKSLNRSPPSYGSHPRGRSSNDSYASYGGPYGGFDGGYGHPPGPIRSHGGPASRYAGGYGYGRGSVGPEFGGGYNNYGGGSLGGYRNEPPLGYSSRFGPYGSGFGGEGYGRGGEGAYLGYPRGGGEGYGGYGGPGYGGAYESGGPGGSYEGAGGPYGRGYSSSSRYHPYAR", "length": 358 }, "evidence": [ { "id": "F1N2T0", "url": "https://omabrowser.org/oma/group/F1N2T0/", "database": "OMA" } ], "glygen_name": "Arabidopsis", "common_name": "Mouse-ear cress" }, { "uniprot_canonical_ac": "Q9Z130-1", "protein_name": "Heterogeneous nuclear ribonucleoprotein D-like", "gene_name": "Hnrnpdl", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MEDMNEYSNIEEFAEGSKINASKNQQDDGKMFIGGLSWDTSKKDLTEYLSRFGEVVDCTIKTDPVTGRSRGFGFVLFKDAASVDKVLELKEHKLDGKLIDPKRAKALKGKEPPKKVFVGGLSPDTSEEQIKEYFGAFGEIENIELPMDTKTNERRGFCFITYTDEEPVKKLLESRYHQIGSGKCEIKVAQPKEVYRQQQQQQKGGRGAAAGGRGGARGRGRGQGQNWNQGFNNYYDQGYGNYNSAYGGDQNYSGYGGYDYTGYNYGNYGYGQGYADYSGQQSTYGKASRGGGNHQNNYQPY", "length": 301 }, "evidence": [ { "id": "F1N2T0", "url": "https://omabrowser.org/oma/group/F1N2T0/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" } ], "go_annotation": { "categories": [ { "name": "Molecular Function", "total": 2, "go_terms": [ { "name": "DNA binding", "id": "GO:0003677", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003677", "evidence": [ { "database": "UniProtKB", "id": "F1N2T0", "url": "https://www.uniprot.org/uniprotkb/F1N2T0" } ], "pmid": "" }, { "name": "RNA binding", "id": "GO:0003723", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003723", "evidence": [ { "database": "UniProtKB", "id": "F1N2T0", "url": "https://www.uniprot.org/uniprotkb/F1N2T0" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 3, "go_terms": [ { "name": "nucleus", "id": "GO:0005634", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005634", "evidence": [ { "database": "UniProtKB", "id": "F1N2T0", "url": "https://www.uniprot.org/uniprotkb/F1N2T0" } ], "pmid": "" }, { "name": "cytoplasm", "id": "GO:0005737", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005737", "evidence": [ { "database": "UniProtKB", "id": "F1N2T0", "url": "https://www.uniprot.org/uniprotkb/F1N2T0" } ], "pmid": "" }, { "name": "nucleoplasm", "id": "GO:0005654", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005654", "evidence": [ { "database": "UniProtKB", "id": "F1N2T0", "url": "https://www.uniprot.org/uniprotkb/F1N2T0" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 1, "go_terms": [ { "name": "DNA-templated transcription", "id": "GO:0006351", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006351", "evidence": [ { "database": "UniProtKB", "id": "F1N2T0", "url": "https://www.uniprot.org/uniprotkb/F1N2T0" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 139, "end_pos": 141, "annotation": "n_glycosylation_sequon" }, { "start_pos": 370, "end_pos": 372, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [ { "pdb_id": "AF-F1N2T0-F1", "pdb_chain": "global", "start_pos": 1, "end_pos": 420, "overlap": "1.0", "method": "AlphaFold", "type": "alphafold", "resolution": -1.0, "url": "https://data.glygen.org/ln2downloads/pdb/current/AF-F1N2T0-F1.pdb", "url_external": "https://alphafold.ebi.ac.uk/entry/F1N2T0" } ], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "F1N2T0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1N2T0" }, { "id": "PS50102", "database": "PROSITE", "url": "https://prosite.expasy.org/PS50102" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "RRM", "eco_id": "ECO_0000259", "start_pos": 148, "end_pos": 230, "start_aa": "Gly", "end_aa": "Glu", "glycosite_overlap": [] } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" }, { "name": "homologset.oma", "label": "OMA Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 139, "end_pos": 141 }, { "start_pos": 370, "end_pos": 372 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ], "tool_support": { "graph_view": "yes" } }, { "uniprot_canonical_ac": "F6R435-1", "uniprot_ac": "F6R435", "uniprot_id": "F6R435_BOVIN", "mass": { "chemical_mass": 55839.0, "monoisotopic_mass": 55839.0 }, "refseq": { "ac": "XP_005223221", "name": "ankyrin repeat and BTB/POZ domain-containing protein 1 isoform X1", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_005223221" }, "gene_names": [ { "name": "ABTB1", "type": "recommended", "evidence": [ { "id": "F6R435", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F6R435" } ] }, { "name": "ABTB1", "type": "synonym", "evidence": [ { "id": "XP_005223221", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_005223221" } ] } ], "protein_names": [ { "name": "Ankyrin repeat and BTB domain containing 1", "type": "synonym", "evidence": [ { "id": "F6R435", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F6R435/entry#names_and_taxonomy" } ] }, { "name": "ankyrin repeat and BTB/POZ domain-containing protein 1 isoform X1", "type": "synonym", "evidence": [ { "id": "XP_005223221", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_005223221" } ] } ], "function": [ { "annotation": "May act as a mediator of the PTEN growth-suppressive signaling pathway. May play a role in developmental processes.", "evidence": [ { "database": "UniProtKB", "id": "A0A3Q1MF49", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1MF49#function" }, { "database": "UniProtKB", "id": "ARBA00053518", "url": "https://www.uniprot.org/uniprotkb/ARBA00053518#function" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Bos taurus", "taxid": 9913, "evidence": [ { "database": "UniProtKB", "id": "F6R435", "url": "https://www.uniprot.org/uniprotkb/F6R435" } ], "common_name": "Bovine", "glygen_name": "Bovine", "reference_species": "Bos taurus [9913]" } ], "gene": [ { "name": "ABTB1", "url": "https://www.uniprot.org/uniprotkb/F6R435", "locus": { "chromosome": "22", "start_pos": 59833036, "end_pos": 59838457, "strand": "+", "evidence": [ { "database": "Ensembl Gene", "id": "ENSBTAG00000018238", "url": "https://www.ensembl.org/id/ENSBTAG00000018238" } ] } } ], "crossref": [ { "id": "F6R435", "url": "https://alphafold.ebi.ac.uk/entry/F6R435", "database": "AlphaFoldDB", "categories": [] }, { "id": "ENSBTAG00000018238", "url": "https://bgee.org/?page=gene&gene_id=ENSBTAG00000018238", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "cd18295", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd18295", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "cd18296", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd18296", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "cd18497", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd18497", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "507417", "url": "https://www.ncbi.nlm.nih.gov/gene/507417", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR000210", "url": "https://www.ebi.ac.uk/interpro/entry/IPR000210", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR002110", "url": "https://www.ebi.ac.uk/interpro/entry/IPR002110", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR011333", "url": "https://www.ebi.ac.uk/interpro/entry/IPR011333", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR036770", "url": "https://www.ebi.ac.uk/interpro/entry/IPR036770", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR044515", "url": "https://www.ebi.ac.uk/interpro/entry/IPR044515", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "EGARCIY", "url": "https://omabrowser.org/oma/group/EGARCIY/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "F6R435", "url": "https://www.orthodb.org/?gene=F6R435", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR46231", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR46231", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR46231:SF1", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR46231:SF1", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00651", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00651", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF12796", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF12796", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "XP_005223221", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_005223221", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A3Q1MF49", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1MF49", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A3Q1MF49-1", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1MF49-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "F6R435", "url": "https://www.uniprot.org/uniprotkb/F6R435", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "F6R435-1", "url": "https://www.uniprot.org/uniprotkb/F6R435-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MDTCDLFSSCRKGDVGRVRYLLEQRDVEVNVRDKWDSTPLYYACLCGHEELVLYLLAHGPPSRVSRELENLAVPELPREVCPSTPAGARCEANTFDGERCLYGAQSDAIRRALRDYRQVTASFWRRDLYYSFLLRLLEQGLHSDVVFVVHGRAFRAHRGVLGARSTYFAHMLDTKWKGRSAVVLRHPLINPVAFGALLQYLYTGCLDVGVEHVSDCERLARQCQLWGLLGGLEAKQASKPGVCMKVLTIEPPQADLQLREDLALLADCALPPELRGDLGELPFPCDGLSSCPDVCFRVGGYDFLCHKAFFCGRSEYFRALLDDHFQESEQLEASGGLPAVTLHSVSPEVFTHVLYYVYSDHTELPPELAYDVLSVADMYLLPGLKQLCGRSLAQLLDEDSVVGVWRVAKLFGLARLEDQCTKYMARVIEKLVQQEDFVEAVREEAAAVAGRQETDSIPLVDDIRFHMGSLVQTCHAMEQAAQRLRVLEELLVSIGLDC", "length": 498, "header": "tr|F6R435-1|F6R435_BOVIN Isoform 1 of Ankyrin repeat and BTB domain containing 1 OS=Bos taurus OX=9913 GN=ABTB1 PE=4 SV=1 CANONICAL=F6R435-1" }, "isoforms": [ { "isoform_ac": "A0A3Q1MF49-1", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1MF49/entry", "sequence": { "sequence": "MDTCDLFSSCRKGDVGRVRYLLEQRDVEVNVRDKWDSTPLYYACLCGHEELVLYLLAHGARCEANTFDGERCLYGAQSDAIRRALRDYRQVTASFWRRDLYYSFLLRLLEQGLHSDVVFVVHGRAFRAHRGVLGARSTYFAHMLDTKWKGRSAVVLRHPLINPVAFGALLQYLYTGCLDVGVEHVSDCERLARQCQLWGLLGGLEAKQASKPGVCMKVLTIEPPQADLQLREDLALLADCALPPELRGDLGELPFPCDGLSSCPDVCFRVGGYDFLCHKAFFCGRSEYFRALLDDHFQESEQLEASGGLPAVTLHSVSPEVFTHVLYYVYSDHTELPPELAYDVLSVADMYLLPGLKQLCGRSLAQLLDEDSVVGVWRVAKLFGLARLEDQCTKYMARVIEKPGADLPRHGAGRAAPAGAGGAAGVHWPGLLTTAHGAIREPGASLWLQRLPPLCLGPRDARLGPRDARLGMRSFSAQTSPRAPGLGTTQGILE", "length": 494, "header": "tr|A0A3Q1MF49-1|F6R435_BOVIN Computationally mapped isoform of Ankyrin repeat and BTB domain containing 1 OS=Bos taurus OX=9913 GN=ABTB1 PE=4 SV=1 CANONICAL=F6R435-1" }, "locus": { "chromosome": "22", "start_pos": 59838429, "end_pos": 59833933, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000075182.2", "url": "https://www.ensembl.org/id/ENSBTAT00000075182.2" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000072808.2", "url": "https://www.ensembl.org/id/ENSBTAP00000072808.2" } ] } }, { "isoform_ac": "F6R435-1", "url": "https://www.uniprot.org/uniprotkb/F6R435/entry", "sequence": { "sequence": "MDTCDLFSSCRKGDVGRVRYLLEQRDVEVNVRDKWDSTPLYYACLCGHEELVLYLLAHGPPSRVSRELENLAVPELPREVCPSTPAGARCEANTFDGERCLYGAQSDAIRRALRDYRQVTASFWRRDLYYSFLLRLLEQGLHSDVVFVVHGRAFRAHRGVLGARSTYFAHMLDTKWKGRSAVVLRHPLINPVAFGALLQYLYTGCLDVGVEHVSDCERLARQCQLWGLLGGLEAKQASKPGVCMKVLTIEPPQADLQLREDLALLADCALPPELRGDLGELPFPCDGLSSCPDVCFRVGGYDFLCHKAFFCGRSEYFRALLDDHFQESEQLEASGGLPAVTLHSVSPEVFTHVLYYVYSDHTELPPELAYDVLSVADMYLLPGLKQLCGRSLAQLLDEDSVVGVWRVAKLFGLARLEDQCTKYMARVIEKLVQQEDFVEAVREEAAAVAGRQETDSIPLVDDIRFHMGSLVQTCHAMEQAAQRLRVLEELLVSIGLDC", "length": 498, "header": "tr|F6R435-1|F6R435_BOVIN Isoform 1 of Ankyrin repeat and BTB domain containing 1 OS=Bos taurus OX=9913 GN=ABTB1 PE=4 SV=1 CANONICAL=F6R435-1" }, "locus": { "chromosome": "22", "start_pos": 59838429, "end_pos": 59834121, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000024279.6", "url": "https://www.ensembl.org/id/ENSBTAT00000024279.6" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000024279.5", "url": "https://www.ensembl.org/id/ENSBTAP00000024279.5" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [], "orthologs": [ { "uniprot_canonical_ac": "A0A287AU56-1", "protein_name": "Ankyrin repeat and BTB domain containing 1", "gene_name": "ABTB1", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MDTCDLFSSCRKGDVGRVRYLLEQRDVEVNVRDKWDSTPLYYACLCGHEELVLYLLANGARCEANTFDGERCLYGAQSDAIRRALREYKQVTSCRRRDHYYSFLLRLLEQGIHSDVVFMVHGRSFRAHRCILGARSAYFANMLDTKWKGKSVVVLRHPLINPVAFGALLQYLYTVASKPGTCVKVLTIEPPQADLRLREDLALLADCALPTELRGDLWELPFPCDGFNGCPDVCFRVEGYNFLCHKAFFCGRSDYFRALLDDHFQENEQLEAQGSLLAITLHGISPDVFTHVLYYVYSDHTELPPEVAYDVLSMADMYLLPGLKQLCGRSLAQLLDEDSVVGVWRVAKLFRLARLEDQCTEYMAKVIEKLVEQDDFVEAVREEAAAVAARQETDSIPLVDDIRFHVGSTVQTCSAMQQAQQRLRVLEDLLVSIGLEC", "length": 437 }, "evidence": [ { "id": "F6R435", "url": "https://omabrowser.org/oma/group/F6R435/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "E7F920-1", "protein_name": "Ankyrin repeat and BTB/POZ domain-containing protein 1", "gene_name": "abtb1", "tax_id": 7955, "organism": "Danio rerio", "sequence": { "sequence": "MDAVDLFSSCRKGDIARVRYLVEQRDVELNIRDKWDSTPLYYACLCGHEELVQYLLANGAKCEANTFDGERCLYGALSDAIRRLLKEYKRITAKAMQRDYYDQFLQTLLEQGNYSDVTFVVHGEMFKAHRCILSARSEYFAHMLETKWKGKSAIALKHPLVNPAAFGAIMQYFYTGRLDIDVNYVEDCKRLAKQCKIGELIEELEVKCKQVYEFVSNKPGTCVKVLTLDPHDFQLQDGMALLADSALPAELRVGYGQLPFDLTDSFPSYPDICFRVEGYDFLCHKAFFCGRSDYFKALLEDHFSEGETLQTHPSIPVITLHDVSHDLFTRILYYIYSDNTQLSHENVYEVLCVADMYLLPGLKRLCGRTLAALLNEENVLHMWRTAKLFRLSRLEDQCTEHMAKIIERLVERPEFADMIREDAGNVAARQETDSIPLVDEIRFHIASNVQTYSAIEEANQKLSALELLLASIGLEC", "length": 476 }, "evidence": [ { "id": "F6R435", "url": "https://omabrowser.org/oma/group/F6R435/", "database": "OMA" } ], "glygen_name": "Zebrafish", "common_name": "Zebrafish" }, { "uniprot_canonical_ac": "F1N9Z2-1", "protein_name": "Ankyrin repeat and BTB/POZ domain-containing protein 1", "gene_name": "ABTB1", "tax_id": 9031, "organism": "Gallus gallus", "sequence": { "sequence": "MDTNDLFTSCKKGDVSRVRYLLEQRDVEINVRDKWDSTPLYYACLCGHEDLVRYLLANGAKCEANTFDGERCLYGALSDAIRRLLKEYKQITAKCMKRDYYDVFLQRLLEQGYQSDIVFIVHGKSFCAHRCILSARSAYFAEMFETKWKGKNMIALKHPLINPTAFGSLLQYLYTGRLDIDVEYVNDCKRLAKQCRLQDLIDDLETKCKKVYEFVSSKPGTCVKVLTIEPTGNCRLQEDLALLADCALPAELRVGFGELPFDSTDNFNSCPDVCFRVADYNFLCHKAFFCGRSDYFKALLEDHFCESEELQTQPSIPVVTLHNISEDIFIRVLYYIYSDDTELSPENAYDVLCVADMYLLPGLKRLCGRTLAQILDEDNVVSIWRIAKLFQLTRLEDQCTEYMAKIIEKLVELEEFVTAVKENAEAVEERQETDSIPLVDDIRFHITSNVQTYSAIEEANQKLEALENLLASIGLDC", "length": 477 }, "evidence": [ { "id": "F6R435", "url": "https://omabrowser.org/oma/group/F6R435/", "database": "OMA" } ], "glygen_name": "Chicken", "common_name": "Chicken" }, { "uniprot_canonical_ac": "G3H7V7-1", "protein_name": "Ankyrin repeat and BTB/POZ domain-containing protein 1", "gene_name": "Abtb1", "tax_id": 10029, "organism": "Cricetulus griseus", "sequence": { "sequence": "MDTSDLFASCRKGDVGRVRYLLEQRDVEVNVRDKWDSTPLYYACLCGHEELVRYLLANGARCEANTFDGERCLYGALSDPIRRALRDYKQVTASCRRRDYYDDFLQRLLEQGIHSDVVFVVHGKPFRAHRCVLGARSTYFANMLDTKWKGKSVVVLRHPLINPVAFGALLQYLYTGRLDIGVEHVSDCERLAKQCQLWDLLEDLEAKCEKVSEFVASKPGTCVKVLTIEPPPADPRLREDMALLADCALPPELRGDLGELPFPCPDGFSSCPDICFRVADSSFLCHKAFFCGRSDYFRALLDDHFRESEEPAASGDPPVVTLHDISPDIFTHVLYYVYSDHTELPPELAYDVLSVADMYLLPGLKRLCGRILAQLLEEDSVVGVWRIAKMFRLARLEDQCTEYMAKVIEKLVEREDFVEAVREEAAAVAARQETDSIPLVDDIRFHVASTVQTYSAIEEAQQRLRALEDLLVSIGLDC", "length": 478 }, "evidence": [ { "id": "F6R435", "url": "https://omabrowser.org/oma/group/F6R435/", "database": "OMA" } ], "glygen_name": "Hamster", "common_name": "Chinese hamster" }, { "uniprot_canonical_ac": "P40560-1", "protein_name": "Ankyrin repeat-containing protein YIL001W", "gene_name": "", "tax_id": 559292, "organism": "Saccharomyces cerevisiae S288C", "sequence": { "sequence": "MADKLMDKNFEELCYSCRTGDMDNVDRLISTGVNVNSVDKFDNSPLFLASLCGHEAVVKLLLQRGAVCDRDRYEGARCIYGALTDTIRDTLLSYDISKAVDVKQPFATHISSMYNDEGFLKRDITFRVSNGKLFTAHKFLLCARSEILAEKMVNEWAKHEIVSLEVRPDIFDIFLKFLYLIPILHQIEPGQYEELIELSSKFDIELLPEFLDKARHTADPTEKSRLMSDYQYKFTEVARSQLLIFVNNCIFRSTVDLANSERRVFSLMNCPAYPDVQLMVKNRNGAIRIYPCHLAVLSRAEYFKVMFTNNFKEKVTYIKAKHVTGKYNSIIPQLTLPNCEFEVAEIILRYLYADNTDIPWMYAVDVLLLADILLEDRLKTIASTIITQSKEFIQQYNVFDVLYLSWEIGVERLEQFAAKFIAIHLQELYKDPEIKRAIMLSSQRISLRQETDTIELVDDIRYYLLRKYSFEPDDVELFENQDDLEYLKQVGYLEYRKDMGMLDNILADLELDV", "length": 513 }, "evidence": [ { "id": "F6R435", "url": "https://omabrowser.org/oma/group/F6R435/", "database": "OMA" } ], "glygen_name": "Yeast", "common_name": "Baker's yeast" }, { "uniprot_canonical_ac": "Q5XIU1-1", "protein_name": "Ankyrin repeat and BTB/POZ domain-containing protein 1", "gene_name": "Abtb1", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MDTSDLFASCRKGDVGRVRYLLEQRDVEVNVRDKWDSTPLYYACLCGHEELVRYLLANGARCEANTFDGERCLYGALSDPIRRALRDYKQVTASCRRRDYYDDFLQRLLEQGIHSDVVFVVHGKPFRAHRCILGARSTYFANMLDTKWKGKSVVVLRHPLINPVAFGALLQYLYTGRLDIGVEHVSDCERLAKQCQLWDLLDDLEAKCEKVSEFVASKPGTCVKVLTIEPPPADPRLRADMALLADCALPPELRGDLGELPFPCPDGFSSCPDICFRVADSSFLCHKAFFCGRSDYFRALLDDHFRESEEPVASGDPPVVTLHDISPDIFTHVLYYVYSDHTELPPELAYDVLSVADMYLLPGLKRLCGRSLAQLLEEDSVVGVWRIAKLFRLARLEDQCTEYMAKVIEKLVEREDFVEAVREEAAAVAARQETDSIPLVDDIRFHVASTVQTYSAIEEAQQQLRALENLLVSIGLDC", "length": 478 }, "evidence": [ { "id": "F6R435", "url": "https://omabrowser.org/oma/group/F6R435/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "Q969K4-1", "protein_name": "Ankyrin repeat and BTB/POZ domain-containing protein 1", "gene_name": "ABTB1", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MDTSDLFASCRKGDVGRVRYLLEQRDVEVNVRDKWDSTPLYYACLCGHEELVLYLLANGARCEANTFDGERCLYGALSDPIRRALRDYKQVTASCRRRDYYDDFLQRLLEQGIHSDVVFVVHGKPFRVHRCVLGARSAYFANMLDTKWKGKSVVVLRHPLINPVAFGALLQYLYTGRLDIGVEHVSDCERLAKQCQLWDLLSDLEAKCEKVSEFVASKPGTCVKVLTIEPPPADPRLREDMALLADCALPPELRGDLWELPFPCPDGFNSCPDICFRVAGCSFLCHKAFFCGRSDYFRALLDDHFRESEEPATSGGPPAVTLHGISPDVFTHVLYYMYSDHTELSPEAAYDVLSVADMYLLPGLKRLCGRSLAQMLDEDTVVGVWRVAKLFRLARLEDQCTEYMAKVIEKLVEREDFVEAVKEEAAAVAARQETDSIPLVDDIRFHVASTVQTYSAIEEAQQRLRALEDLLVSIGLDC", "length": 478 }, "evidence": [ { "id": "F6R435", "url": "https://omabrowser.org/oma/group/F6R435/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "Q99LJ2-1", "protein_name": "Ankyrin repeat and BTB/POZ domain-containing protein 1", "gene_name": "Abtb1", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MDTSDLFASCRKGDVGRVRYLLEQRDVEVNVRDKWDSTPLYYACLCGHEELVRYLLANGARCEANTFDGERCLYGALSDPIRRALRDYKQVTASCRRRDYYDDFLQRLLEQGIHSDVVFVVHGKPFRAHRCILGARSTYFANMLDTKWKGKSVVVLRHPLINPVAFGALLQYLYTGRLDIGVEHVSDCERLAKQCQLWDLLDDLEAKCEKVSEFVASKPGTCVKVLTIEPPPADPRLRADMALLADCALPSELRGDLGELPFPCPDGFSSCPDICFRVADSSFLCHKAFFCGRSDYFRALLDDHFQESEEPAASGDPPVVTLHDISPDIFIHVLYYVYSDHTELPPELAYDVLSVADMYLLPGLKRLCGRSLAQLLEEDSVVGVWRIAKMFRLARLEDQCTEYMAKVIEKLVEREDFVEAVREEAAAVAARQETDSIPLVDDIRFHVASTVQTYSAIEEAQQRLRALEDLLVSIGLDC", "length": 478 }, "evidence": [ { "id": "F6R435", "url": "https://omabrowser.org/oma/group/F6R435/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" } ], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 2, "go_terms": [ { "name": "cytoplasm", "id": "GO:0005737", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005737", "evidence": [ { "database": "UniProtKB", "id": "F6R435", "url": "https://www.uniprot.org/uniprotkb/F6R435" } ], "pmid": "" }, { "name": "cytosol", "id": "GO:0005829", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005829", "evidence": [ { "database": "UniProtKB", "id": "F6R435", "url": "https://www.uniprot.org/uniprotkb/F6R435" } ], "pmid": "" } ] }, { "name": "Molecular Function", "total": 1, "go_terms": [ { "name": "translation elongation factor activity", "id": "GO:0003746", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003746", "evidence": [ { "database": "UniProtKB", "id": "F6R435", "url": "https://www.uniprot.org/uniprotkb/F6R435" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [ { "pdb_id": "AF-F6R435-F1", "pdb_chain": "global", "start_pos": 1, "end_pos": 498, "overlap": "1.0", "method": "AlphaFold", "type": "alphafold", "resolution": -1.0, "url": "https://data.glygen.org/ln2downloads/pdb/current/AF-F6R435-F1.pdb", "url_external": "https://alphafold.ebi.ac.uk/entry/F6R435" } ], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "F6R435", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F6R435" }, { "id": "PS50097", "database": "PROSITE", "url": "https://prosite.expasy.org/PS50097" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "BTB", "eco_id": "ECO_0000259", "start_pos": 143, "end_pos": 210, "start_aa": "Ser", "end_aa": "Val", "glycosite_overlap": [] } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" }, { "name": "homologset.oma", "label": "OMA Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ], "tool_support": { "graph_view": "yes" } }, { "uniprot_canonical_ac": "F1N4N7-1", "uniprot_ac": "F1N4N7", "uniprot_id": "F1N4N7_BOVIN", "mass": { "chemical_mass": 143494.0, "monoisotopic_mass": 143494.0 }, "refseq": { "ac": "XP_002686374", "name": "VWFA and cache domain-containing protein 1", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_002686374" }, "gene_names": [ { "name": "CACHD1", "type": "recommended", "evidence": [ { "id": "F1N4N7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1N4N7" } ] }, { "name": "CACHD1", "type": "synonym", "evidence": [ { "id": "XP_002686374", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_002686374" } ] } ], "protein_names": [ { "name": "VWFA and cache domain-containing protein 1", "type": "recommended", "evidence": [ { "id": "F1N4N7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1N4N7/entry#names_and_taxonomy" } ] }, { "name": "VWFA and cache domain-containing protein 1", "type": "synonym", "evidence": [ { "id": "XP_002686374", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_002686374" } ] } ], "function": [ { "annotation": "May regulate voltage-dependent calcium channels.", "evidence": [ { "database": "UniProtKB", "id": "A0AAA9TTW9", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TTW9#function" }, { "database": "UniProtKB", "id": "ARBA00053598", "url": "https://www.uniprot.org/uniprotkb/ARBA00053598#function" }, { "database": "UniProtKB", "id": "A0A3Q1MFT4", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1MFT4#function" }, { "database": "UniProtKB", "id": "F1N4N7", "url": "https://www.uniprot.org/uniprotkb/F1N4N7#function" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Bos taurus", "taxid": 9913, "evidence": [ { "database": "UniProtKB", "id": "F1N4N7", "url": "https://www.uniprot.org/uniprotkb/F1N4N7" } ], "common_name": "Bovine", "glygen_name": "Bovine", "reference_species": "Bos taurus [9913]" } ], "gene": [ { "name": "CACHD1", "url": "https://www.uniprot.org/uniprotkb/F1N4N7", "locus": { "chromosome": "3", "start_pos": 80788720, "end_pos": 81022577, "strand": "+", "evidence": [ { "database": "Ensembl Gene", "id": "ENSBTAG00000016455", "url": "https://www.ensembl.org/id/ENSBTAG00000016455" } ] } } ], "crossref": [ { "id": "ENSBTAG00000016455", "url": "https://bgee.org/?page=gene&gene_id=ENSBTAG00000016455", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "536020", "url": "https://www.ncbi.nlm.nih.gov/gene/536020", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR002035", "url": "https://www.ebi.ac.uk/interpro/entry/IPR002035", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR029151", "url": "https://www.ebi.ac.uk/interpro/entry/IPR029151", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR036465", "url": "https://www.ebi.ac.uk/interpro/entry/IPR036465", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR051173", "url": "https://www.ebi.ac.uk/interpro/entry/IPR051173", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "bta:536020", "url": "https://www.genome.jp/dbget-bin/www_bget?bta:536020", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "NTHPYLS", "url": "https://omabrowser.org/oma/group/NTHPYLS/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "A0A3Q1MFT4", "url": "https://www.orthodb.org/?gene=A0A3Q1MFT4", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "F1N4N7", "url": "https://www.orthodb.org/?gene=F1N4N7", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR10166", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR10166", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR10166:SF68", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR10166:SF68", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF27776", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF27776", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "XP_002686374", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_002686374", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A3Q1MFT4", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1MFT4", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A3Q1MFT4-1", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1MFT4-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0AAA9TTW9", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TTW9", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0AAA9TTW9-1", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TTW9-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "F1N4N7", "url": "https://www.uniprot.org/uniprotkb/F1N4N7", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "F1N4N7-1", "url": "https://www.uniprot.org/uniprotkb/F1N4N7-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MTREPEEEEAAGAAALARGSRGSLGRIQARRPPLWLLCLAVGWLLGAGADAEFSILDEAQVLASQMRRLAAEELGVVTMQRIFNSFVYTEKISNGESEVQQLAKKIREKFNRYLDVVNRNKQVVEASYTAHLTSPLTAIQDCCTIPPSMMEFDGNFNTNVSRTISCDRLSTTVNSRAFNPGRDLNSVLADNLKSNPGIKWQYFSSEEGIFTVFPAHKFRCKGSYEHRSRPIYVSTVRPQSKQVVVILDHGASVTDTQLQIAKDAAQVILSAIDEHDKISVLTVADTVRTCSLDQCYKTFLSPATSETKRKMSTFVSSVKSLDSPTQHAVGFQKAFQLIRSTNNSTKFQANTDMVIIYLSAGITSKDSSEEDKKATLRVINEENSFLNNSVMILTYALMNDGVTGLKELAFLRDLAEQNSGKYGVLDRIALPVIKGSMMVLNQLSNLETTVGRFYTNLPNRMIDEAVFSLPFSDEMGDGLIMTVSKPCYFGNLLLGIVGVDVNLAYILEDVTYYQDSLASYTFLIDDKGYTLMHPSLTRPYLLSEPPLHTDIIHYENIPKFELVRQNILSLPLGSQIIAVPVNSSLSWHINKLRETGKEAYNVSYAWKMVQDTSFILCIVVIQPEIPVKQLKNLNTVPSSKLLYHRLDLLGQPSACLHFKQLATLESPTVMLSAGSFSSPYEHLSQPETKRMVEHYTAYLSDNTRLIANPGLKFSVRNEVMATSHVTDEWMTQMEMSSLNTYIVRRYIATPNGVLRIYPGSLMDKAFDPTRRQWYLHAVANPGLISLTGPYLDVGGAGYVVTISHTIHSSSTQLSSGHTVAVMGIDFTLRYFYKVLMDLLPVCNQDGGNKIRCFIMEDRGYLVAHPTLIDPKGHAPVEQQHITHKEPLVANDILNHPNFVKKNLCNSFSDRTVQRFYKFNTSLVGDLTNLVHGSHCSKYRLARIPGTNAFVGIVNETCDSLAFCACSMVDRLCLNCHRMEQNECECPCECPLEVNECTGNLTNAENRNPSCEVHQEPVTYTAIDPGLQDALHQCVNSRCSQRTESGDCFGVLDCEWCMVDSDGKTHLDKSYCAPQKECFGGIVGAKSPYVDDMGSIGDEVVTLNMIKSAPVGPVAGGIMGCIMVLVLAVYAYRHQIHRRSHQHMSPLAAQEMSVRMSNLENDRDERDDDGPEDRGIISNTRFIAAVIERHAHSPERRRRYWGRSGTESDHGYSTMSPQEDSENPPCTNDPLSAGVDVGNHDEDLELDTPPQTAALLSHKFHHYRLHHPTLHHSHHLQAAVTVHTVDAEC", "length": 1288, "header": "tr|F1N4N7-1|F1N4N7_BOVIN Isoform 1 of VWFA and cache domain-containing protein 1 OS=Bos taurus OX=9913 GN=CACHD1 PE=3 SV=2 CANONICAL=F1N4N7-1" }, "isoforms": [ { "isoform_ac": "A0A3Q1MFT4-1", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1MFT4/entry", "sequence": { "sequence": "MTREPEEEEAAGAAALARGSRGSLGRIQARRPPLWLLCLAVGWLLGAGADAEFSILDEAQVLASQMRRLAAEELGVVTMQRIFNSFVYTEKISNGESEVQQLAKKIREKFNRYLDVVNRNKQVVEASYTAHLTSPLTAIQDCCTIPPSMMEFDGNFNTNVSRTISCDRLSTTVNSRAFNPGRDLNSVLADNLKSNPGIKWQYFSSEEGIFTVFPAHKFRCKGSYEHRSRPIYVSTVRPQSKQVVVILDHGASVTDTQLQIAKDAAQVILSAIDEHDKISVLTVADTVRTCSLDQCYKTFLSPATSETKRKMSTFVSSVKSLDSPTQHAVGFQKAFQLIRSTNNSTKFQANTDMVIIYLSAGITSKDSSEEDKKATLRVINEENSFLNNSVMILTYALMNDGVTGLKELAFLRDLAEQNSGKYGVLDRIALPVIKGSMMVLNQLSNLETTVGRFYTNLPNRMIDEAVFSLPFSDEMGDGLIMTVSKPCYFGNLLLGIVGVDVNLAYILEDVTYYQDSLASYTFLIDDKGYTLMHPSLTRPYLLSEPPLHTDIIHYENIPKFELVRQNILSLPLGSQIIAVPVNSSLSWHINKLRETGKEAYNVSYAWKMVQDTSFILCIVVIQPEIPVKQLKNLNTVPSSKLLYHRLDLLGQPSACLHFKQLATLESPTVMLSAGSFSSPYEHLSQPETKRMVEHYTAYLSDNTRLIANPGLKFSVRNEVMATSHVTDEWMTQMEMSSLNTYIVRRYIATPNGVLRIYPGSLMDKAFDPTRRQWYLHAVANPGLISLTGPYLDVGGAGYVVTISHTIHSSSTQLSSGHTVAVMGIDFTLRYFYKVLMDLLPVCNQDGGNKIRCFIMEDRGYLVAHPTLIDPKGHAPVEQQHITHKEPLVANDILNHPNFVKKNLCNSFSDRTVQRFYKFNTSLVGDLTNLVHGSHCSKYRLARIPGTNAFVGIVNETCDSLAFCACSMVDRLCLNCHRMEQNECECPCECPLEVNECTGNLTNAENRDCFGVLDCEWCMVDSDGKTHLDKSYCAPQKECFGGIVGAKSPYVDDMGSIGDEVVTLNMIKSAPVGPVAGGIMGCIMVLVLAVYAYRHQIHRRSHQHMSPLAAQEMSVRMSNLENDRDERDDDGPEDRGIISNTRFIAAVIERHAHSPERRRRYWGRSGTESDHGYSTMSPQEDSENPPCTNDPLSAGVDVGNHDEDLELDTPPQTAALLSHKFHHYRLHHPTLHHSHHLQAAVTVHTVDAEC", "length": 1249, "header": "tr|A0A3Q1MFT4-1|F1N4N7_BOVIN Computationally mapped isoform of VWFA and cache domain-containing protein 1 OS=Bos taurus OX=9913 GN=CACHD1 PE=3 SV=1 CANONICAL=F1N4N7-1" }, "locus": { "chromosome": "3", "start_pos": 81022378, "end_pos": 80789724, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000083954.2", "url": "https://www.ensembl.org/id/ENSBTAT00000083954.2" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000069396.1", "url": "https://www.ensembl.org/id/ENSBTAP00000069396.1" } ] } }, { "isoform_ac": "A0AAA9TTW9-1", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TTW9/entry", "sequence": { "sequence": "MTREPEEEEAAGAAALARGSRGSLGRIQARRPPLWLLCLAVGWLLGAGADAEFSILDEAQVLASQMRRLAAEELGVVTMQRIFNSFVYTEKISNGESEVQQLAKKIREKFNRYLDVVNRNKQVVEASYTAHLTSPLTAIQDCCTIPPSMMEFDGNFNTNVSRTISCDRLSTTVNSRAFNPGRDLNSVLADNLKSNPGIKWQYFSSEEGIFTVFPAHKFRCKGSYEHRSRPIYVSTVRPQSKQVVVILDHGASVTDTQLQIAKDAAQVILSAIDEHDKISVLTVADTVRTCSLDQCYKTFLSPATSETKRKMSTFVSSVKSLDSPTQHAVGFQKAFQLIRSTNNSTKFQANTDMVIIYLSAGITSKDSSEEDKKATLRVINEENSFLNNSVMILTYALMNDGVTGLKELAFLRDLAEQNSGKYGVLDRIALPVIKGSMMVLNQLSNLETTVGRFYTNLPNRMIDEAVFSLPFSDEMGDGLIMTVSKPCYFGNLLLGIVGVDVNLAYILEDVTYYQDSLASYTFLIDDKGYTLMHPSLTRPYLLSEPPLHTDIIHYENIPKFELVRQNILSLPLGSQIIAVPVNSSLSWHINKLRETGKEAYNVSYAWKMVQDTSFILCIVVIQPEIPVKQLKNLNTVPSSKLLYHRLDLLGQPSACLHFKQLATLESPTVMLSAGSFSSPYEHLSQPETKRMVEHYTAYLSDNTRLIANPGLKFSVRNEVMATSHVTDEWMTQMEMSSLNTYIVRRYIATPNGVLRIYPGSLMDKAFDPTRRQWYLHAVANPGLISLTGPYLDVGGAGYVVTISHTIHSSSTQLSSGHTVAVMGIDFTLRYFYKVLMDLLPVCNQDGGNKIRCFIMEDRGYLVAHPTLIDPKGHAPVEQQHITHKEPLVANDILNHPNFVKKNLCNSFSDRTVQRFYKFNTSLVGDLTNLVHGSHCSKYRLARIPGTNAFVGIVNETCDSLAFCACSMVDRLCLNCHRMEQNECECPCECPLEVNECTGNLTNAENRNPSCEVHQEPVTYTAIDPGLQDALHQCVNSRCSQRTESGDCFGVLDCEWCMVDSDGKTHLDKSYCAPQKECFGGIVGAKSPYVDDMGSIGYSTMSPQEDSENPPCTNDPLSAGVDVGNHDEDLELDTPPQTAALLSHKFHHYRLHHPTLHHSHHLQAAVTVHTVDAEC", "length": 1174, "header": "tr|A0AAA9TTW9-1|F1N4N7_BOVIN Computationally mapped isoform of VWFA and cache domain-containing protein 1 OS=Bos taurus OX=9913 GN=CACHD1 PE=3 SV=1 CANONICAL=F1N4N7-1" }, "locus": { "chromosome": "3", "start_pos": 81022378, "end_pos": 80789724, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000113801.1", "url": "https://www.ensembl.org/id/ENSBTAT00000113801.1" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000100529.1", "url": "https://www.ensembl.org/id/ENSBTAP00000100529.1" } ] } }, { "isoform_ac": "F1N4N7-1", "url": "https://www.uniprot.org/uniprotkb/F1N4N7/entry", "sequence": { "sequence": "MTREPEEEEAAGAAALARGSRGSLGRIQARRPPLWLLCLAVGWLLGAGADAEFSILDEAQVLASQMRRLAAEELGVVTMQRIFNSFVYTEKISNGESEVQQLAKKIREKFNRYLDVVNRNKQVVEASYTAHLTSPLTAIQDCCTIPPSMMEFDGNFNTNVSRTISCDRLSTTVNSRAFNPGRDLNSVLADNLKSNPGIKWQYFSSEEGIFTVFPAHKFRCKGSYEHRSRPIYVSTVRPQSKQVVVILDHGASVTDTQLQIAKDAAQVILSAIDEHDKISVLTVADTVRTCSLDQCYKTFLSPATSETKRKMSTFVSSVKSLDSPTQHAVGFQKAFQLIRSTNNSTKFQANTDMVIIYLSAGITSKDSSEEDKKATLRVINEENSFLNNSVMILTYALMNDGVTGLKELAFLRDLAEQNSGKYGVLDRIALPVIKGSMMVLNQLSNLETTVGRFYTNLPNRMIDEAVFSLPFSDEMGDGLIMTVSKPCYFGNLLLGIVGVDVNLAYILEDVTYYQDSLASYTFLIDDKGYTLMHPSLTRPYLLSEPPLHTDIIHYENIPKFELVRQNILSLPLGSQIIAVPVNSSLSWHINKLRETGKEAYNVSYAWKMVQDTSFILCIVVIQPEIPVKQLKNLNTVPSSKLLYHRLDLLGQPSACLHFKQLATLESPTVMLSAGSFSSPYEHLSQPETKRMVEHYTAYLSDNTRLIANPGLKFSVRNEVMATSHVTDEWMTQMEMSSLNTYIVRRYIATPNGVLRIYPGSLMDKAFDPTRRQWYLHAVANPGLISLTGPYLDVGGAGYVVTISHTIHSSSTQLSSGHTVAVMGIDFTLRYFYKVLMDLLPVCNQDGGNKIRCFIMEDRGYLVAHPTLIDPKGHAPVEQQHITHKEPLVANDILNHPNFVKKNLCNSFSDRTVQRFYKFNTSLVGDLTNLVHGSHCSKYRLARIPGTNAFVGIVNETCDSLAFCACSMVDRLCLNCHRMEQNECECPCECPLEVNECTGNLTNAENRNPSCEVHQEPVTYTAIDPGLQDALHQCVNSRCSQRTESGDCFGVLDCEWCMVDSDGKTHLDKSYCAPQKECFGGIVGAKSPYVDDMGSIGDEVVTLNMIKSAPVGPVAGGIMGCIMVLVLAVYAYRHQIHRRSHQHMSPLAAQEMSVRMSNLENDRDERDDDGPEDRGIISNTRFIAAVIERHAHSPERRRRYWGRSGTESDHGYSTMSPQEDSENPPCTNDPLSAGVDVGNHDEDLELDTPPQTAALLSHKFHHYRLHHPTLHHSHHLQAAVTVHTVDAEC", "length": 1288, "header": "tr|F1N4N7-1|F1N4N7_BOVIN Isoform 1 of VWFA and cache domain-containing protein 1 OS=Bos taurus OX=9913 GN=CACHD1 PE=3 SV=2 CANONICAL=F1N4N7-1" }, "locus": { "chromosome": "3", "start_pos": 81022378, "end_pos": 80789724, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000021878.6", "url": "https://www.ensembl.org/id/ENSBTAT00000021878.6" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000021878.5", "url": "https://www.ensembl.org/id/ENSBTAP00000021878.5" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [ { "id": "bta:536020", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?bta:536020", "resource": "KEGG Pathway" } ], "orthologs": [ { "uniprot_canonical_ac": "A0A8I6A388-1", "protein_name": "VWFA and cache domain-containing protein 1", "gene_name": "Cachd1", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MAREPEEEETVRTAALVRRCPRCPGWPGAPRPPFWLLCLVACWILGAVADADFSILDEAQVLASQMRRLAAEELGVVTMQRIFNSLVYTEKISNGESEVQQLAKKIREKFNRYLDVVNRNKQVVEASYTAHLTSPLTAIQDCCTIPPSMMEFDGNFNTNVSRTVSCDRLSTTVNSRAFNPGRDLNSVLADNLKSNPGIKWQYFSSEEGIFTVFPAHKFRCKGSYEHRSRPIYVSTVRPQSKHIVVILDHGASVTDTQLQIAKDAAQVILSAIDEHDKISVLTVADTVRTCSLDQCYKTYLSPATSETKRKMSTFVSSVKPSDSPTQHAVGFHRAFQLIRSTSNNTRFQANTDMVIIYLSAGITSKDSSEEDKKATLRVINEENGFLNNSVMILTYALMNDGVTGLKELAFLRDLAEQNSGKYGIPDRTALPVIKGSMMVLNQLSNLETTVGRFYTNLPNRMIDEAVFSLPFSDEMGDGLIMTVSKPCYFGNLLLGIVGVDVNLAYILEDVTYYQDSLASYTFLIDDKGYTLMHPSLTRPYLLSEPPLHTDIIHYENIPKFELVRQNILSLPLGSQIITVPVNSSLSWHINKLRETGKEAYNVSYAWKMVQDTSFILCIVVIQPEIPVKQLKNLNTVPSSKLLYHRLDLLGQPSACLHFKQLATLESPTVMLSAGSFSSPYEHLSQPETKRMVEHYTAYLSDNTRLIANPGLKFSVRNEVMATSHVTDEWMTQMEMSSLNTYIVRRYIATPNGVLRIYPGSLMDKAFDPTRRQWYLHAVANPGLISLTGPYLDVGGAGYVVTISHTIHSSSTQLSSGHTVAVMGIDFTLRYFYKVLMDLLPVCNQDGGNKIRCFIMEDRGYLVAHPTLVDPKGHAPLEQQHITHKEPLVANDILNHPNFVKKNLCNSFSDRTVQRSYKFNTSLVGDLTNLVHGSHCSKYRLTRIPGTNAFVGIVNETCDSLAFCACSMVDRLCLNCHRMEQNECECPCECPLEVNECTGNLTNAENRNPSCEVHQEPVTYTAIDPGLQDALHQCVNSRCNQRMESGDCFGVLDCEWCVVDSDGKTHLDKSYCAPQKECFGGIVGAKSPYVDDMGAIGDEVITLNMIKSAPVGPVAGGIMGCIMVLVLAVYAYRHQIHRRSHQHMSPLAAQEMSVRMSNLENDRDEREDDSHEDRGIISNTRFIAAVMERHAHSPERRRRYWGRSGTESDHGYSTMSPQEDSENPPCNNDPLSAGVDVGNHDDDLDLDTPPQTAALLSHKFHHYRSHHPTLHHSHHLQAAVTVHTVDAEC", "length": 1288 }, "evidence": [ { "id": "F1N4N7", "url": "https://omabrowser.org/oma/group/F1N4N7/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "A0A8V0ZSJ7-1", "protein_name": "VWFA and cache domain-containing protein 1", "gene_name": "CACHD1", "tax_id": 9031, "organism": "Gallus gallus", "sequence": { "sequence": "MMERKCLVAQVANVALAMEIKATAAWTGVIWFSPKPEVLHRAQTACRIWQPRGSHEALRCKATQLGSGADGSLTRGMPCSGTPARCHHAYRRFTSSGVGLEAISSLQRIFNSFMYTEKISNGESEVQQLAKKIREKFNRYLDVVNRNKQVVEASYTAHLTSPLTAIQDCCTIPPSMMEFDGNFNTNVSRTISCDRLSTTVNSRAFNPGRDLNSVLADNLKSNPGIKWQYFSSEEGIFTVFPAHKFRCKGSYEHRSRPVYVSTVRPQSKHIVVIVDHGASVTETQLQIAKDAAQVILSSIDEHDKISVLTVADTVRTCSLDQCYKTFLSPATSETKRKMSTFVSSIKSSDSPTQHAIGFQKAFQLIRNTNNGTKLQGNTDMVIISLSAGITSKDSSEDDKKATLRVINEENSFLNNSVMILTYALMNEGVTGLKELAFLRDLAEQNSVKYGVPDRTTLPVIKGSMMVLNQLSNLETTVGRFYTNLPNRMIDEAVFSLPFSDEMGDGLIMTVSKPCYFGNLLLGIVGVDVNLAYILEDVTYYQDSLGSYTFLIDNKGYTLMHPSLTRPYLLSEPPLHTDIIHYENIPKFELVRQNILSIPLGSQIITVPVNSSLSWHVNKLREVGKEAYNVSYAWKMVQDTSFILCVVVIQPEIPVKQLKNLNTVPSSKLLYHRLDLLGQPNACLHFKQLATLESPTVMLSAGSFSSPYEHLSQPETKRMVEHYTAYLSDNTRLIANPGLKFSVRNEVMATSHVTDEWMTQMEMSSYEQLNSYIVRRYIATPNGVLRIYPGSLMDKAFDPTRRQWYLHAVANPGLITFTGPYLDVGGAGYVVTISHTIHSSSAQMSSGHSVAVMGIDFTLRYFYKVLMDLLPVCNQDGGNKIRCFIMEDRGYLVAHPTLIDPKGHAPVEQQHITHKEPLVANDILNHPNFVKKNLCNSFSDRTVQRFYKFNTSLVGDLTNLVHGSHCSKYRLTRIPGTNAFVGIVNETCDSLAFCACSMVDRLCLNCHRMEQNECECPCECPLEVNECTGNLTNAESRNPSCEVHQEPMTFTAIDPSLQDALPQCINTQCNQRTESGDCFGVLDCEWCMVDSDGKTHLDKSYCAPQKECFGGIVGAKSPYVDDLGAIGDEVITLNMIKSAPVGPVAGGIMGCIMVLVLAVYAYRHQIHRRSHQHMSPLAAQEMSVRMSNLENDRDERDDDSHEDRGIISNTRFIAAVIERHAHSPERRRRYWGRSGTESDHGYSTMSPQEDSENPPCNNDPLSAGVDVGNHDEDLDLDTPPQTAALLSHKFHHYRLHHPTLHHSHHLQAAVTVHTVDAEC", "length": 1318 }, "evidence": [ { "id": "F1N4N7", "url": "https://omabrowser.org/oma/group/F1N4N7/", "database": "OMA" } ], "glygen_name": "Chicken", "common_name": "Chicken" }, { "uniprot_canonical_ac": "E7F5Q0-1", "protein_name": "VWFA and cache domain-containing protein 1", "gene_name": "cachd1", "tax_id": 7955, "organism": "Danio rerio", "sequence": { "sequence": "MASRSRTGPRFSFAAWSKHSRPNWNNLEISKWSLVALLVFACCGFCGADSEFSILEEAQVLAVQMKKLSTQELGVLTMQRIFNSFVYTEKTSNGETEVQQLAKKIREKFNRYLDVVNRNKQVVEASYTAHLTSPLTAIQDCCSIPPSMMEFDGNFNANVSKTVSCDRLSPTVNSRAFNPGRDLNSVLADNLKSNPGIKWQYFSSEEGIFTLFPAHKFHCKGTFEHRSRPVYVAAVRPQSKHIVVIIDHGASVTETQLQIARDAALVILNSIDEHDKISVLTIADTVRSCSLDQCYKSFLSPATSETKRKMSTFISNIKASDSSTQHAVGFQKAFQLLRNTSNVTRQLTNTDMMIIYLSSGITSRDSSEHEKRATLSAVKEENRHLNNSVMILTYALMNDGVTGLKELAFLRDLAEQNSLKYGVQDRSALPVVKGSMMVLNQLSNLETTVGRFYINLPNRMIDVATFSLPYADQMGDGFIMTVSRPCYFGNLLLGVVGVDVNLAYILEDVTYYQDSLASYTFLIDNKGYTLMHPSLTRPYLMTEAPLHTDIIHYENIPGFPVVRQNILSLPLGSQVIAVPVNSSLSWHMNRLRDPNRDAYNVSYAWKLVQDTSFILCIVYVQPEIPVKQLKNLNTAPSSKLLYHRLDLLGQPSSCLHFKQLATVESPTVMLSAGSFSSPYEHLSQPETKRMVEHYTAYLSDNTRLIANPGLKSSVRNEVMATSHVTDEWMSLMEMSSLNCYIVRRYIATPNGVLRIYPGSLMDKAFDPTRRQWYLHAVANPGLITFTGPYLDVGGAGYVVTISHTIHAPSSQMASGYTVAVMGIDFTLRYFYKVLLDLLPICNQDKGNKIRCFIMEDRGYLVAHPTLIDPKGHAPAEQQHITHKEPLVANDILNHPNFVKKNLCNSFSDRTVQRFYKFNTSIVGDLTNLVHGSHCSKYRLTRIPGTNAFAGIVNETCDALAFCACSTVDRLCLNCHRMEQNECECPCECPLEVNECTGNLTNAENRNPSCDVHQEPLSLTVIEPSLQDTLPQCINTRCSQRFTSSDCFGVLDCEWCMVDSDGKTHLDKPYCALQKECFGGIVGAKSPYVDGMGILDEELASLNMIKSAPVGPVAGGIMGCIMVLVLAVYAYRHQIHRRSHQHMSPLAAQEMSVRMSNLDNERDDRDEDSHEDRGIISNTRFIAAVIERHTHSPERRRRYWGRSGTESDHGYSTMSPQEDSENPPCNNDPLSAGVDVGNHDEDLDLDTPPQTAALLSHKFHPYRHPHMHHPLHLHTHHLQAAVTVHSVDAEC", "length": 1290 }, "evidence": [ { "id": "F1N4N7", "url": "https://omabrowser.org/oma/group/F1N4N7/", "database": "OMA" } ], "glygen_name": "Zebrafish", "common_name": "Zebrafish" }, { "uniprot_canonical_ac": "Q5BI42-1", "protein_name": "VWFA and cache domain-containing protein CG16868", "gene_name": "", "tax_id": 7227, "organism": "Drosophila melanogaster", "sequence": { "sequence": "MWPNSNLNAVLLILAVLACPTSSQHVPLAMANSTSNQVPTDPGFMPLQQSPGSVFFVHHNQQNAMQLRHSMEGKLRNIRNTELRVAKIQEIFDSMHFSSAKGASNTRQASSNDSNVVNPQLQRDLQLFSERLSKKIQKATYVVLELRELLRYNLTKVWQYSYDDEDDESESEMDLEMELEDLHARNTASPTDEHVQLYLNTQIESCQPDYETDLEYGSSSTQSIHYNRQQIQILNYLKSDDARATFLNENNARSLAVNGYISNQLVLLKRRLSRSDAENSNSKPISGNHFKHIYFLSNSDGASASLHFRQLYVSAIKQKFVLFLIDVGSALSAELFDLSKSFVHEMLQLLEDTDKVSLVTVASEANFMSLEAFPAEAGHGIYSATRAHKEEIISFINSLSRAQAFTNHSLGFEYSFELLHRLQQSGMINTAEQPVEFVYITRGLLTNLSDAMAVLRVVADGQRRLRAPVIINTCAVVLDEKRIMYEKQFLNDVASQNYTKYEIDVASWWPSGQEASELVGRFYVLSKMHAETSLPQTSSRIFGPLFQERYLSDTLEVHPPVVDADSGDVLVSITHAVPPYGVVGVNLYLSDLLEDLLNYPSTTSSAKQGLGYAFLLDRSTGNTLAHPAFPRPLIQRETSYPVNIAYLENATDFSSHIRDRLLREESGNVTTDVYVGRQRLQRTYYWQSVLGFYVLCLVSSGGDTLRNVSSTQRYNLKDTVSNYEPGYYGESMDLLYHRLDLNQGGSAPPKTCRYFRQVATMDAPTLFLSAAAFESPFGFLHNNRPRTQLRHVESIMAYLRDSSGLLANMGLRPSIRHEVGVLYQAMQQLRRRHQDARGSLRSHVIRRYIASVSGVLQLYPGCLLSSSYDPTRRPWFRQAIAQPGKIVSTAPYLDAGGAGYIITIAHTIFEGKAHALHSAQQDRPVAVVALDVPYAFYYRLILEGTPICQLPHIKCLLFEHEGYLLAHPSMLQPATLTKNQRRPHEHLTHKESYLANDMLNHGQLVRKLGCASYQNRTLQRYYAFNTSLSSILGNVVHGERTKYAIALIRGSNLFAAVLNSSCDGGAFCPCSTIDRECLNCKRMDQTDCECPCECPMVGDSSSPSSLMYFANYTRQFPYCPPPSEHFIALPPTTQLLSTLPNCPGSAGICETYSTQRECLGVMGCEWCQLDVDGNSFSTSFCSSQASCFNGVLASLTPYGELDEMELLAAHNPQREQHAYSAFGPLGGAIVVLVMVIGFAIYCYRHNLDAQTQEHFYVDSVQEENYGLPLSRFNFDDCKAHDEPPLGGGYDHASAQRQLMHAADISPYHVSSGSSYRRPPNGESDHGYSTMTPHEDSSDQQCFTLAEPLLLHDKRHSKSDTMSISTSISSPTNRQQSSSQPNTHPYLSNQPTSKTERYKQVQATPSPCRGTPAGGSVYGQTTLPLEGDKTRPHYILAPVTVHRHMETAES", "length": 1449 }, "evidence": [ { "id": "F1N4N7", "url": "https://omabrowser.org/oma/group/F1N4N7/", "database": "OMA" } ], "glygen_name": "Fruit fly", "common_name": "Fruit fly" }, { "uniprot_canonical_ac": "Q5VU97-1", "protein_name": "VWFA and cache domain-containing protein 1", "gene_name": "CACHD1", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MARQPEEEETAVARARRPPLWLLCLVACWLLGAGAEADFSILDEAQVLASQMRRLAAEELGVVTMQRIFNSFVYTEKISNGESEVQQLAKKIREKFNRYLDVVNRNKQVVEASYTAHLTSPLTAIQDCCTIPPSMMEFDGNFNTNVSRTISCDRLSTTVNSRAFNPGRDLNSVLADNLKSNPGIKWQYFSSEEGIFTVFPAHKFRCKGSYEHRSRPIYVSTVRPQSKHIVVILDHGASVTDTQLQIAKDAAQVILSAIDEHDKISVLTVADTVRTCSLDQCYKTFLSPATSETKRKMSTFVSSVKSSDSPTQHAVGFQKAFQLIRSTNNNTKFQANTDMVIIYLSAGITSKDSSEEDKKATLQVINEENSFLNNSVMILTYALMNDGVTGLKELAFLRDLAEQNSGKYGVPDRMALPVIKGSMMVLNQLSNLETTVGRFYTNLPNRMIDEAVFSLPFSDEMGDGLIMTVSKPCYFGNLLLGIVGVDVNLAYILEDVTYYQDSLASYTFLIDDKGYTLMHPSLTRPYLLSEPPLHTDIIHYENIPKFELVRQNILSLPLGSQIIAVPVNSSLSWHINKLRETGKEAYNVSYAWKMVQDTSFILCIVVIQPEIPVKQLKNLNTVPSSKLLYHRLDLLGQPSACLHFKQLATLESPTIMLSAGSFSSPYEHLSQPETKRMVEHYTAYLSDNTRLIANPGLKFSVRNEVMATSHVTDEWMTQMEMSSLNTYIVRRYIATPNGVLRIYPGSLMDKAFDPTRRQWYLHAVANPGLISLTGPYLDVGGAGYVVTISHTIHSSSTQLSSGHTVAVMGIDFTLRYFYKVLMDLLPVCNQDGGNKIRCFIMEDRGYLVAHPTLIDPKGHAPVEQQHITHKEPLVANDILNHPNFVKKNLCNSFSDRTVQRFYKFNTSLAGDLTNLVHGSHCSKYRLARIPGTNAFVGIVNETCDSLAFCACSMVDRLCLNCHRMEQNECECPCECPLEVNECTGNLTNAENRNPSCEVHQEPVTYTAIDPGLQDALHQCVNSRCSQRLESGDCFGVLDCEWCMVDSDGKTHLDKPYCAPQKECFGGIVGAKSPYVDDMGAIGDEVITLNMIKSAPVGPVAGGIMGCIMVLVLAVYAYRHQIHRRSHQHMSPLAAQEMSVRMSNLENDRDERDDDSHEDRGIISNTRFIAAVIERHAHSPERRRRYWGRSGTESDHGYSTMSPQEDSENPPCNNDPLSAGVDVGNHDEDLDLDTPPQTAALLSHKFHHYRSHHPTLHHSHHLQAAVTVHTVDAEC", "length": 1274 }, "evidence": [ { "id": "F1N4N7", "url": "https://omabrowser.org/oma/group/F1N4N7/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "Q6PDJ1-1", "protein_name": "VWFA and cache domain-containing protein 1", "gene_name": "Cachd1", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": 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2898566, "strand": "-", "evidence": [ { "database": "Ensembl Gene", "id": "ENSBTAG00000004502", "url": "https://www.ensembl.org/id/ENSBTAG00000004502" } ] } } ], "crossref": [ { "id": "F6PWT1", "url": "https://alphafold.ebi.ac.uk/entry/F6PWT1", "database": "AlphaFoldDB", "categories": [] }, { "id": "ENSBTAG00000004502", "url": "https://bgee.org/?page=gene&gene_id=ENSBTAG00000004502", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "617589", "url": "https://www.ncbi.nlm.nih.gov/gene/617589", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR019366", "url": "https://www.ebi.ac.uk/interpro/entry/IPR019366", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "RKVYGNM", "url": "https://omabrowser.org/oma/group/RKVYGNM/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "A0A3Q1LWV3", "url": "https://www.orthodb.org/?gene=A0A3Q1LWV3", "database": "OrthoDB", "categories": [ "Protein Classification" ] 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] } }, { "isoform_ac": "A0A3Q1MIN4-1", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1MIN4/entry", "sequence": { "sequence": "MSFRDLRNFTEMMRALGYPRHISMENFRTPNFGLVSEVLLWLVKRYEPQNDIPSDVETEQDRVFFIKAIAQFMATKAHIKLNTKKLYQADGYAVKELLKITSVLYNAMKTKGMEGSKRAEEDVSKFKFDLGSKIADLKAARQLASEITSKGASLYDLLGKEVELRELRTEAVARPLEINETEKVMRIAIKDILAQVQKTKDLLNNVASDEANLEAKIEKRKLELERNRKRLQTLQSVRPAFMDEYEKIEEELQKQYEIYLEKFRNLAYLEQQLEDHHRMEQERFEETENTLRLMQNKLKEEGKRLLKSGSQPGVPDAALGDKPAWSVSPSERPGTGNGDSDVDIQEDDESDSELEERRLSQLRTAMEVLTQGQPSKHVVGTMQGGDTDDDEDLEDSEIDMEDDEDDDDLEDESVALSAAKPSRRGRKPEPLEESDSDF", "length": 438, "header": "tr|A0A3Q1MIN4-1|F6PWT1_BOVIN Computationally mapped isoform of Clusterin associated protein 1 OS=Bos taurus OX=9913 GN=CLUAP1 PE=3 SV=1 CANONICAL=F6PWT1-1" }, "locus": { "chromosome": "25", "start_pos": 2927789, "end_pos": 2898600, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000073726.3", "url": "https://www.ensembl.org/id/ENSBTAT00000073726.3" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000069034.1", "url": "https://www.ensembl.org/id/ENSBTAP00000069034.1" } ] } }, { "isoform_ac": "A0A3Q1MNU9-1", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1MNU9/entry", "sequence": { "sequence": "MSFRDLRNFTEMMRALGYPRHISMENFRTPNFGLVSEVLLWLVKRYEPQNDIPSDVETEQDRVFFIKAIAQFMATKAHIKLNTKKLYQADGYAVKELLKITSVLYNAMKTKGMEGSKRAEEDVSKFKFDLGSKIADLKAARQLASEITSKGASLYDLLGKEVELRELRTEAVARPLEINETEKVMRIAIKDILAQVQKTKDLLNNVASDEANLEAKIEKRKLELERNRKRLQTLQSVRPAFMDEYEKIEEELQKQYEIYLEKFRNLAYLEQQLEDHHRMEQERFEVTVTLTLTSRRTMNPTANWKRGGCPSCARPWRCSRKDNPASTSWARCRVETRMMTKTWRTVRLTWRTTKTTMTWRTRAWHSQRPSPVEEAGNLSHWRRVTVTSDLRAKGPGQMKTRGFVGKGGIKEAEEKRRLLDKPAGLVNEAKPASGLVSWVLLTHSKA", "length": 446, "header": "tr|A0A3Q1MNU9-1|F6PWT1_BOVIN Computationally mapped isoform of Clusterin associated protein 1 OS=Bos taurus OX=9913 GN=CLUAP1 PE=3 SV=3 CANONICAL=F6PWT1-1" }, "locus": { "chromosome": "25", "start_pos": 2927964, "end_pos": 2898600, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000068658.3", "url": "https://www.ensembl.org/id/ENSBTAT00000068658.3" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000071301.3", "url": "https://www.ensembl.org/id/ENSBTAP00000071301.3" } ] } }, { "isoform_ac": "F6PWT1-1", "url": "https://www.uniprot.org/uniprotkb/F6PWT1/entry", "sequence": { "sequence": "MSFRDLRNFTEMMRALGYPRHISMENFRTPNFGLVSEVLLWLVKRYEPQNDIPSDVETEQDRVFFIKAIAQFMATKAHIKLNTKKLYQADGYAVKELLKITSVLYNAMKTKGMEGSKRAEEDVSKFKFDLGSKIADLKAARQLASEITSKGASLYDLLGKEVELRELRTEAVARPLEINETEKVMRIAIKDILAQVQKTKDLLNNVASDEANLEAKIEKRKLELERNRKRLQTLQSVRPAFMDEYEKIEEELQKQYEIYLEKFRNLAYLEQQLEDHHRMEQERFEETENTLRLMQNKLKEEGKRLLKSGSNGDSDVDIQEDDESDSELEERRLSQLRTAMEVLTQGQPSKHVVGTMQGGDTDDDEDLEDSEIDMEDDEDDDDLEDESVALSAAKPSRRGRKPEPLEESDSDF", "length": 412, "header": "tr|F6PWT1-1|F6PWT1_BOVIN Isoform 1 of Clusterin associated protein 1 OS=Bos taurus OX=9913 GN=CLUAP1 PE=3 SV=2 CANONICAL=F6PWT1-1" }, "locus": { "chromosome": "25", "start_pos": 2927789, "end_pos": 2898600, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000052696.4", "url": "https://www.ensembl.org/id/ENSBTAT00000052696.4" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000048673.3", "url": "https://www.ensembl.org/id/ENSBTAP00000048673.3" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [ { "id": "R-BTA-5620924", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-BTA-5620924", "resource": "Reactome", "description": "Intraflagellar transport" } ], "orthologs": [ { "uniprot_canonical_ac": "A0A8V0Z465-1", "protein_name": "Clusterin associated protein 1", "gene_name": "CLUAP1", "tax_id": 9031, "organism": "Gallus gallus", "sequence": { "sequence": "MSYRDVRNLTEMLRALGYPRLVSMENFHAPNFALVAELLLWLVRRYEPQSDIPPDVETEQDRVFFIKAVAQFMATKAHIKLNTKKLYQADGYAVRELLKVTSVLYSAMNTEGMERTDITEEDSSKFKFDLGSKIADLKAARQLASEITSKGANLYDLLGKEVELREARTESIARPLEINEAEKMMKVAIDCVLEEVQKTKDMLSNVALDEANLEAKIEKRKSELERSQKRLQTLQSVRPAFMDEYEKIEEQLQKQYTSYLEKFHNLTYLEQLLDDQHRTEQEMFEEAANMLRLMQNRLKEEEQRLLKSGSNDDSDMEIQEDEGSDSEVEDRQFRKQRTALDTLVPGRAGARIVGAMQGGDTEEDEESGDSEIDLDDDEDEEEDVEDDSMEISPSKSSHRAKKPEPLEESDNDF", "length": 413 }, "evidence": [ { "id": "F6PWT1", "url": "https://omabrowser.org/oma/group/F6PWT1/", "database": "OMA" } ], "glygen_name": "Chicken", "common_name": "Chicken" } ], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 8, "go_terms": [ { "name": "cilium", "id": "GO:0005929", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005929", "evidence": [ { "database": "UniProtKB", "id": "F6PWT1", "url": "https://www.uniprot.org/uniprotkb/F6PWT1" } ], "pmid": "" }, { "name": "nucleoplasm", "id": "GO:0005654", "url": 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"end_pos": 10 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": 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[ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ], "tool_support": { "graph_view": "yes" } }, { "uniprot_canonical_ac": "F1N746-1", "uniprot_ac": "F1N746", "uniprot_id": "F1N746_BOVIN", "mass": { "chemical_mass": 121564.0, "monoisotopic_mass": 121564.0 }, "refseq": { "ac": "NP_001178338", "name": "rab GTPase-activating protein 1", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001178338" }, "gene_names": [ { "name": "RABGAP1", "type": "recommended", "evidence": [ { "id": "F1N746", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1N746" } ] }, { "name": "RABGAP1", "type": "synonym", "evidence": [ { "id": "NP_001178338", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001178338" } ] } ], "protein_names": [ { "name": "Rab GTPase-activating protein 1", "type": "recommended", "evidence": [ { "id": "F1N746", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1N746/entry#names_and_taxonomy" } ] }, { "name": "GAP and centrosome-associated protein", "type": "synonym", "evidence": [ { "id": "F1N746", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1N746/entry#names_and_taxonomy" } ] }, { "name": "Rab6 GTPase-activating protein GAPCenA", "type": "synonym", "evidence": [ { "id": "F1N746", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1N746/entry#names_and_taxonomy" } ] }, { "name": "rab GTPase-activating protein 1", "type": "synonym", "evidence": [ { "id": "NP_001178338", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001178338" } ] } ], "function": [ { "annotation": "May act as a GTPase-activating protein of RAB6A. May play a role in microtubule nucleation by centrosome. May participate in a RAB6A-mediated pathway involved in the metaphase-anaphase transition.", "evidence": [ { "database": "UniProtKB", "id": "A0A3Q1MIP8", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1MIP8#function" }, { "database": "UniProtKB", "id": "ARBA00056651", "url": "https://www.uniprot.org/uniprotkb/ARBA00056651#function" }, { "database": "UniProtKB", "id": "A0A3Q1MV99", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1MV99#function" }, { "database": "UniProtKB", "id": "F1N746", "url": "https://www.uniprot.org/uniprotkb/F1N746#function" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Bos taurus", "taxid": 9913, "evidence": [ { "database": "UniProtKB", "id": "F1N746", "url": "https://www.uniprot.org/uniprotkb/F1N746" } ], "common_name": "Bovine", "glygen_name": "Bovine", "reference_species": "Bos taurus [9913]" } ], "gene": [ { "name": "RABGAP1", "url": "https://www.uniprot.org/uniprotkb/F1N746", "locus": { "chromosome": "11", "start_pos": 94264860, "end_pos": 94096281, "strand": "-", "evidence": [ { "database": "Ensembl Gene", "id": "ENSBTAG00000039172", "url": "https://www.ensembl.org/id/ENSBTAG00000039172" } ] } } ], "crossref": [ { "id": "F1N746", "url": "https://alphafold.ebi.ac.uk/entry/F1N746", "database": "AlphaFoldDB", "categories": [] }, { "id": "ENSBTAG00000039172", "url": "https://bgee.org/?page=gene&gene_id=ENSBTAG00000039172", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "cd01211", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd01211", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "519260", "url": "https://www.ncbi.nlm.nih.gov/gene/519260", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR000195", "url": "https://www.ebi.ac.uk/interpro/entry/IPR000195", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR006020", "url": "https://www.ebi.ac.uk/interpro/entry/IPR006020", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR011993", "url": "https://www.ebi.ac.uk/interpro/entry/IPR011993", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR022164", "url": "https://www.ebi.ac.uk/interpro/entry/IPR022164", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR035969", "url": "https://www.ebi.ac.uk/interpro/entry/IPR035969", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR050302", "url": "https://www.ebi.ac.uk/interpro/entry/IPR050302", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "bta:519260", "url": "https://www.genome.jp/dbget-bin/www_bget?bta:519260", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "MHSMGYV", "url": "https://omabrowser.org/oma/group/MHSMGYV/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "F1N746", "url": "https://www.orthodb.org/?gene=F1N746", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR47219", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR47219", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR47219:SF6", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR47219:SF6", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00566", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00566", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF00640", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00640", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF12473", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF12473", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF23436", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF23436", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "R-BTA-8854214", "url": "https://www.reactome.org/PathwayBrowser/#R-BTA-8854214", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "NP_001178338", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001178338", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A3Q1MIP8", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1MIP8", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A3Q1MIP8-1", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1MIP8-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A3Q1MV99", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1MV99", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A3Q1MV99-1", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1MV99-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "F1N746", "url": "https://www.uniprot.org/uniprotkb/F1N746", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "F1N746-1", "url": "https://www.uniprot.org/uniprotkb/F1N746-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MDDKASVGKISVSSDSVSTLNSEDFVLVSRQGDETPSTNNGSDDEKTGLKIIGNGSEQQLQKELADVLMDPPMDDQPGDKELVERSQLDGEGDGPLSNQLSASSTINPVSLVGLQKPEMSLPVKPGQGDSEGSSPFTPVADEDSVVFSKLTYLGCASVNAPRSEVEALRMMSILRGQCQISLDVTLSVPNVSEGTVRLLDPQTNTEIANYPIYKILFCVRGHDGTPESDCFAFTESHYNAELFRIHVFRCEIQEAVSRILYSFATAFRRSAKQTPLSATAAPQTPDSDIFTFSVSLEIKEDDGKGYFSAVPKDKDRQCFKLRQGIDKKIVIYVQQTTNKELAIERCFGLLLSPGKDVRNSDMHLLDLESMGKSSDGKSYVITGSWNPKSPHFQVVNEETPKDKVLFMTTAVDLVITEVQEPVRFLLETKVRVCSPNERLFWPFSKRSTTENFFLKLKQIKQKERKNNTDTLYEVVCLESESERERRKTTASPSIRLPQSGSQSSMIPSPPEDDEEEDNDEPLLSGSGDVSKECAEKILETWGELLSKWHLNLSVRPKQLSSLVRSGVPEALRGEVWQLLAGCHNNDHLVEKYRILITKESPQDSAITRDINRTFPAHDYFKDTGGDGQDSLYKICKAYSVYDEEIGYCQGQSFLAAVLLLHMPEEQAFSVLVKIMFDYGLRELFKQNFEDLHCKFYQLERLMQEYIPDLYNHFLDISLEAHMYASQWFLTLFTAKFPLYMVFHIIDLLLCEGISVIFNVALGLLKTSKDDLLLTDFEGALKFFRVQLPKRYRSEENAKKLMELACNMKISQKKLKKYEKEYHTMREQQAQQEDPIERFERENRRLQEANMRLEQENDDLAHELVTSKIALRKDLDNAEEKADALNKELLMTKQKLIDAEEEKRRLEEESAQLKEMCRRELDKAESEIKKNSSIIGDYKQICSQLSERLEKQQAANKVEIEKIRQKVDDCERCREFFNKEGRIKGMGSAKEVVDEDTDEEKETLKNQLREMELELAQTKLQLVEAECKIQDLEHHLGLALNEVQAAKKTWFNRTLSSIKTATGVQGKETC", "length": 1069, "header": "tr|F1N746-1|F1N746_BOVIN Isoform 1 of Rab GTPase-activating protein 1 OS=Bos taurus OX=9913 GN=RABGAP1 PE=4 SV=3 CANONICAL=F1N746-1" }, "isoforms": [ { "isoform_ac": "A0A3Q1MIP8-1", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1MIP8/entry", "sequence": { "sequence": "MDDKASVGKISVSSDSVSTLNSEDFVLVSRQGDETPSTNNGSDDEKTGLKIIGNGSEQQLQKELADVLMDPPMDDQPGDKELVERSQLDGEGDGPLSNQLSASSTINPVSLVGLQKPEMSLPVKPGQGDSEGSSPFTPVADEDSVVFSKLTYLGCASVNAPRSEVEALRMMSILRGQCQISLDVTLSVPNVSEGTVRLLDPQTNTEIANYPIYKILFCVRGHDGTPESDCFAFTESHYNAELFRIHVFRCEIQEAVSRILYSFATAFRRSAKQTPLSATAAPQTPDSDIFTFSVSLEIKEDDGKGYFSAVPKDKDRQCFKLRQGIDKKIVIYVQQTTNKELAIERCFGLLLSPGKDVRNSDMHLLDLESMGKSSDGKSYVITGSWNPKSPHFQVVNEETPKDKVLFMTTAVDLVITEVQEPVRFLLETKVRVCSPNERLFWPFSKRSTTENFFLKLKQIKQKERKNNTDTLYEVVCLESESERERRKTTASPSIRLPQSGSQSSMIPSPPEDDEEEDNDEPLLSGSGDVSKECAEKILETWGELLSKWHLNLSVRPKQLSSLVRSGVPEALRGEVWQLLAGCHNNDHLVEKYRILITKAYSVYDEEIGYCQGQSFLAAVLLLHMPEEQAFSVLVKIMFDYGLRELFKQNFEDLHCKFYQLERLMQEYIPDLYNHFLDISLEAHMYASQWFLTLFTAKFPLYMVFHIIDLLLCEGISVIFNVALGLLKTSKDDLLLTDFEGALKFFRVQLPKRYRSEENAKKLMELACNMKISQKKLKKYEKEYHTMREQQAQQEDPIERFERENRRLQEANMRLEQENDDLAHELVTSKIALRKDLDNAEEKADALNKELLMTKQKLIDAEEEKRRLEEESAQLKEMCRRELDKAESEIKKNSSIIGDYKQICSQLSERLEKQQAANKVEIEKIRQKVDDCERCREFFNKEGRIKGMGSAKEVVDEDTDEEKETLKNQLREMELELAQTKLQLVEAECKIQDLEHHLGLALNEVQAAKKTWFNRTLSSIKTATGVQGKETC", "length": 1031, "header": "tr|A0A3Q1MIP8-1|F1N746_BOVIN Computationally mapped isoform of Rab GTPase-activating protein 1 OS=Bos taurus OX=9913 GN=RABGAP1 PE=4 SV=2 CANONICAL=F1N746-1" }, "locus": { "chromosome": "11", "start_pos": 94263938, "end_pos": 94123586, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000079937.2", "url": "https://www.ensembl.org/id/ENSBTAT00000079937.2" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000069049.2", "url": "https://www.ensembl.org/id/ENSBTAP00000069049.2" } ] } }, { "isoform_ac": "A0A3Q1MV99-1", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1MV99/entry", "sequence": { "sequence": "MDDKASVGKISVSSDSVSTLNSEDFVLVSRQGDETPSTNNGSDDEKTGLKIIGNGSEQQLQKELADVLMDPPMDDQPGDKELVERSQLDGEGDGPLSNQLSASSTINPVSLVGLQKPEMSLPVKPGQGDSEGSSPFTPVADEDSVVFSKLTYLGCASVNAPRSEVEALRMMSILRGQCQISLDVTLSVPNVSEGTVRLLDPQTNTEIANYPIYKILFCVRGHDGTPESDCFAFTESHYNAELFRIHVFRCEIQEAVSRILYSFATAFRRSAKQTPLSATAAPQTPDSDIFTFSVSLEIKEDDGKGYFRCFGLLLSPGKDVRNSDMHLLDLESMGKSSDGKSYVITGSWNPKSPHFQVVNEETPKDKVLFMTTAVDLVITEVQEPVRFLLETKVRVCSPNERLFWPFSKRSTTENFFLKLKQIKQKERKNNTDTLYEVVCLESESERERRKTTASPSIRLPQSGSQSSMIPSPPEDDEEEDNDEPLLSGSGDVSKECAEKILETWGELLSKWHLNLSVRPKQLSSLVRSGVPEALRGEVWQLLAGCHNNDHLVEKYRILITKESPQDSAITRDINRTFPAHDYFKDTGGDGQDSLYKICKAYSVYDEEIGYCQGQSFLAAVLLLHMPEEQAFSVLVKIMFDYGLRELFKQNFEDLHCKFYQLERLMQEYIPDLYNHFLDISLEAHMYASQWFLTLFTAKFPLYMVFHIIDLLLCEGISVIFNVALGLLKTSKDDLLLTDFEGALKFFRVQLPKRYRSEENAKKLMELACNMKISQKKLKKYEKEYHTMREQQAQQEDPIERFERENRRLQEANMRLEQENDDLAHELVTSKIALRKDLDNAEEKADALNKELLMTKQKLIDAEEEKRRLEEESAQLKEMCRRELDKAESEIKKNSSIIGDYKQICSQLSERLEKQQAANKVEIEKIRQKVDDCERCREFFNKEGRIKGMGSAKEVVDEDTDEEKETLKNQLREMELELAQTKLQLVEAECKIQDLEHHLGLALNEVQAAKKTWFNRTLSSIKTATGVQGKETC", "length": 1032, "header": "tr|A0A3Q1MV99-1|F1N746_BOVIN Computationally mapped isoform of Rab GTPase-activating protein 1 OS=Bos taurus OX=9913 GN=RABGAP1 PE=4 SV=2 CANONICAL=F1N746-1" }, "locus": { "chromosome": "11", "start_pos": 94263938, "end_pos": 94123586, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000069770.2", "url": "https://www.ensembl.org/id/ENSBTAT00000069770.2" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000058896.2", "url": "https://www.ensembl.org/id/ENSBTAP00000058896.2" } ] } }, { "isoform_ac": "F1N746-1", "url": "https://www.uniprot.org/uniprotkb/F1N746/entry", "sequence": { "sequence": "MDDKASVGKISVSSDSVSTLNSEDFVLVSRQGDETPSTNNGSDDEKTGLKIIGNGSEQQLQKELADVLMDPPMDDQPGDKELVERSQLDGEGDGPLSNQLSASSTINPVSLVGLQKPEMSLPVKPGQGDSEGSSPFTPVADEDSVVFSKLTYLGCASVNAPRSEVEALRMMSILRGQCQISLDVTLSVPNVSEGTVRLLDPQTNTEIANYPIYKILFCVRGHDGTPESDCFAFTESHYNAELFRIHVFRCEIQEAVSRILYSFATAFRRSAKQTPLSATAAPQTPDSDIFTFSVSLEIKEDDGKGYFSAVPKDKDRQCFKLRQGIDKKIVIYVQQTTNKELAIERCFGLLLSPGKDVRNSDMHLLDLESMGKSSDGKSYVITGSWNPKSPHFQVVNEETPKDKVLFMTTAVDLVITEVQEPVRFLLETKVRVCSPNERLFWPFSKRSTTENFFLKLKQIKQKERKNNTDTLYEVVCLESESERERRKTTASPSIRLPQSGSQSSMIPSPPEDDEEEDNDEPLLSGSGDVSKECAEKILETWGELLSKWHLNLSVRPKQLSSLVRSGVPEALRGEVWQLLAGCHNNDHLVEKYRILITKESPQDSAITRDINRTFPAHDYFKDTGGDGQDSLYKICKAYSVYDEEIGYCQGQSFLAAVLLLHMPEEQAFSVLVKIMFDYGLRELFKQNFEDLHCKFYQLERLMQEYIPDLYNHFLDISLEAHMYASQWFLTLFTAKFPLYMVFHIIDLLLCEGISVIFNVALGLLKTSKDDLLLTDFEGALKFFRVQLPKRYRSEENAKKLMELACNMKISQKKLKKYEKEYHTMREQQAQQEDPIERFERENRRLQEANMRLEQENDDLAHELVTSKIALRKDLDNAEEKADALNKELLMTKQKLIDAEEEKRRLEEESAQLKEMCRRELDKAESEIKKNSSIIGDYKQICSQLSERLEKQQAANKVEIEKIRQKVDDCERCREFFNKEGRIKGMGSAKEVVDEDTDEEKETLKNQLREMELELAQTKLQLVEAECKIQDLEHHLGLALNEVQAAKKTWFNRTLSSIKTATGVQGKETC", "length": 1069, "header": "tr|F1N746-1|F1N746_BOVIN Isoform 1 of Rab GTPase-activating protein 1 OS=Bos taurus OX=9913 GN=RABGAP1 PE=4 SV=3 CANONICAL=F1N746-1" }, "locus": { "chromosome": "11", "start_pos": 94263938, "end_pos": 94123586, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000061025.3", "url": "https://www.ensembl.org/id/ENSBTAT00000061025.3" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000053675.3", "url": "https://www.ensembl.org/id/ENSBTAP00000053675.3" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [ { "id": "bta:519260", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?bta:519260", "resource": "KEGG Pathway" }, { "id": "R-BTA-8854214", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-BTA-8854214", "resource": "Reactome", "description": "TBC/RABGAPs" } ], "orthologs": [ { "uniprot_canonical_ac": "A2AWA9-1", "protein_name": "Rab GTPase-activating protein 1", "gene_name": "Rabgap1", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MDDKASVGKISVSSDSVSTLNSEDFVLVSRQGDETPSTNNGSDDEKTGLKIVGNGSEQQLQKELADVLMDPPMDDQPGERSQLDGEGDGPLSNQLSASSTINPVPLVGLPKPEMSLPVKPGQGDSEVSSPFTPVADEDSVVFNKLTYLGCASVNAPRSEVEALRMMSILRSQCQISLDVTLSVPNVSEGTVRLLDPQTNTEIANYPIYKILFCVRGHDGTPESDCFAFTESHYNAELFRIHVFRCEIQEAVSRILYSFATAFRRSAKQTPLSATAAPQTPDSDIFTFSVSLEIKEDDGKGYFSAVPKDKDRQCFKLRQGIDKKIVICVQQTANKELAIERCFGLLLSPGKDVRNSDMHLLDLESMGKSSDGKSYVITGSWNPKSPHFQVVNEETPKDKVLFMTTAVDLVITEVQEPVRFLLETKVRVCSPNERLFWPFSKRSTTENFFLKLKQIKQKEKKNNADTLYEVVCLESESERERRKTTASPSVRLPQSGSQSSMIPSPPEDDEEEDNDEPLLSGFGDVSKECAEKILETWGELLSKWHLNLSVRPKQLSSLVRSGVPEALRGEVWQLLAGCHNNDHLVEKYRILITKESPQDSAITRDINRTFPAHDYFKDTGGDGQDSLYKICKAYSVYDEEIGYCQGQSFLAAVLLLHMPEEQAFSVLVKIMFDYGLRELFKQNFEDLHCKFYQLERLMQEYIPDLYNHFLDISLEAHMYASQWFLTLFTAKFPLYMVFHIIDLLLCEGISVIFNVALGLLKTSKDDLLLTDFEGALKFFRVQLPKRYRSEENAKRLMELACNTKISQKKLKKFEKEYHTMREQQAQQEDPIERFERENRRLQEANMRLEQENDDLAHELVTSKIALRKDLDNAEEKADALNKELLMTKQKLIDAEDEKRRLEEESAQLKEMCRRELDKAESEIKKNSSIIGDYKQICSQLSERLEKQQTANKVEIEKIRQKVDDCDRCRDFFNKEGRVKGISSAKGVSDEDTDEEKETLKNQLREMELELAQTKLQLVEAECKIQDLEHHLGLALSEVQAAKKTWFNRTLSSIKTATGVQGKETC", "length": 1064 }, "evidence": [ { "id": "F1N746", "url": "https://omabrowser.org/oma/group/F1N746/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "A8JNN5-1", "protein_name": "GTPase activating protein and centrosome-associated, isoform B", "gene_name": "GAPcenA", "tax_id": 7227, "organism": "Drosophila melanogaster", "sequence": { "sequence": 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"length": 1194 }, "evidence": [ { "id": "F1N746", "url": "https://omabrowser.org/oma/group/F1N746/", "database": "OMA" } ], "glygen_name": "Fruit fly", "common_name": "Fruit fly" }, { "uniprot_canonical_ac": "D3ZX42-1", "protein_name": "Rab GTPase-activating protein 1", "gene_name": "Rabgap1", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": 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"length": 1065 }, "evidence": [ { "id": "F1N746", "url": "https://omabrowser.org/oma/group/F1N746/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "F1P0U3-1", "protein_name": "Rab GTPase-activating protein 1", "gene_name": "RABGAP1", "tax_id": 9031, "organism": "Gallus gallus", "sequence": { "sequence": 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"length": 1069 }, "evidence": [ { "id": "F1N746", "url": "https://omabrowser.org/oma/group/F1N746/", "database": "OMA" } ], "glygen_name": "Chicken", "common_name": "Chicken" }, { "uniprot_canonical_ac": "Q9Y3P9-1", "protein_name": "Rab GTPase-activating protein 1", "gene_name": "RABGAP1", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": 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"length": 1069 }, "evidence": [ { "id": "F1N746", "url": "https://omabrowser.org/oma/group/F1N746/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" } ], "go_annotation": { "categories": [ { "name": "Molecular Function", "total": 2, "go_terms": [ { "name": "GTPase activator activity", "id": "GO:0005096", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005096", "evidence": [ { "database": "UniProtKB", "id": "F1N746", "url": "https://www.uniprot.org/uniprotkb/F1N746" } ], "pmid": "" }, { "name": "small GTPase binding", "id": "GO:0031267", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0031267", "evidence": [ { "database": "UniProtKB", "id": "F1N746", "url": "https://www.uniprot.org/uniprotkb/F1N746" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 2, "go_terms": [ { "name": "centrosome", "id": "GO:0005813", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005813", "evidence": [ { "database": "UniProtKB", "id": "F1N746", "url": "https://www.uniprot.org/uniprotkb/F1N746" } ], "pmid": "" }, { "name": "cytosol", "id": "GO:0005829", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005829", "evidence": [ { "database": "UniProtKB", "id": "F1N746", "url": "https://www.uniprot.org/uniprotkb/F1N746" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 1051, "end_pos": 1053, "annotation": "n_glycosylation_sequon" }, { "start_pos": 190, "end_pos": 192, "annotation": "n_glycosylation_sequon" }, { "start_pos": 40, "end_pos": 42, "annotation": "n_glycosylation_sequon" }, { "start_pos": 466, "end_pos": 468, "annotation": "n_glycosylation_sequon" }, { "start_pos": 54, "end_pos": 56, "annotation": "n_glycosylation_sequon" }, { "start_pos": 551, "end_pos": 553, "annotation": "n_glycosylation_sequon" }, { "start_pos": 611, "end_pos": 613, "annotation": "n_glycosylation_sequon" }, { "start_pos": 930, "end_pos": 932, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [ { "pdb_id": "AF-F1N746-F1", "pdb_chain": "global", "start_pos": 1, "end_pos": 1069, "overlap": "1.0", "method": "AlphaFold", "type": "alphafold", "resolution": -1.0, "url": "https://data.glygen.org/ln2downloads/pdb/current/AF-F1N746-F1.pdb", "url_external": "https://alphafold.ebi.ac.uk/entry/F1N746" } ], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "F1N746", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1N746" }, { "id": "PS01179", "database": "PROSITE", "url": "https://prosite.expasy.org/PS01179" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "PID", "eco_id": "ECO_0000259", "start_pos": 152, "end_pos": 267, "start_aa": "Tyr", "end_aa": "Phe", "glycosite_overlap": [] }, { "evidence": [ { "id": "F1N746", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1N746" }, { "id": "PS50086", "database": "PROSITE", 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"tool_support": { "graph_view": "yes" } }, { "uniprot_canonical_ac": "F1N3Y8-1", "uniprot_ac": "F1N3Y8", "uniprot_id": "F1N3Y8_BOVIN", "mass": { "chemical_mass": 58726.0, "monoisotopic_mass": 58726.0 }, "refseq": { "ac": "NP_001179278", "name": "Fanconi anemia group E protein", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001179278" }, "gene_names": [ { "name": "FANCE", "type": "recommended", "evidence": [ { "id": "F1N3Y8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1N3Y8" } ] }, { "name": "FANCE", "type": "synonym", "evidence": [ { "id": "NP_001179278", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001179278" } ] } ], "protein_names": [ { "name": "FA complementation group E", "type": "synonym", "evidence": [ { "id": "F1N3Y8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1N3Y8/entry#names_and_taxonomy" } ] }, { "name": "Fanconi anemia complementation group E", "type": "synonym", "evidence": [ { "id": "NP_001179278", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001179278" } ] }, { "name": "Fanconi anemia group E protein", "type": "synonym", "evidence": [ { "id": "NP_001179278", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001179278" } ] } ], "function": [], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Bos taurus", "taxid": 9913, "evidence": [ { "database": "UniProtKB", "id": "F1N3Y8", "url": "https://www.uniprot.org/uniprotkb/F1N3Y8" } ], "common_name": "Bovine", "glygen_name": "Bovine", "reference_species": "Bos taurus [9913]" } ], "gene": [ { "name": "FANCE", "url": "https://www.uniprot.org/uniprotkb/F1N3Y8", "locus": { "chromosome": "23", "start_pos": 9425305, "end_pos": 9415933, "strand": "-", "evidence": [ { "database": "Ensembl Gene", "id": "ENSBTAG00000019492", "url": "https://www.ensembl.org/id/ENSBTAG00000019492" } ] } } ], "crossref": [ { "id": "F1N3Y8", "url": "https://alphafold.ebi.ac.uk/entry/F1N3Y8", "database": "AlphaFoldDB", "categories": [] }, { "id": "ENSBTAG00000019492", "url": "https://bgee.org/?page=gene&gene_id=ENSBTAG00000019492", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "cd07439", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd07439", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "513464", "url": "https://www.ncbi.nlm.nih.gov/gene/513464", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR021025", "url": "https://www.ebi.ac.uk/interpro/entry/IPR021025", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR039685", "url": "https://www.ebi.ac.uk/interpro/entry/IPR039685", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "bta:513464", "url": "https://www.genome.jp/dbget-bin/www_bget?bta:513464", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "LRLPWIC", "url": "https://omabrowser.org/oma/group/LRLPWIC/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "A0A3Q1MJJ3", "url": "https://www.orthodb.org/?gene=A0A3Q1MJJ3", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "F1N3Y8", "url": "https://www.orthodb.org/?gene=F1N3Y8", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR32094", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR32094", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR32094:SF5", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR32094:SF5", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF11510", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF11510", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "R-BTA-6783310", "url": "https://www.reactome.org/PathwayBrowser/#R-BTA-6783310", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "R-BTA-9833482", "url": "https://www.reactome.org/PathwayBrowser/#R-BTA-9833482", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "NP_001179278", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001179278", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A3Q1MJJ3", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1MJJ3", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A3Q1MJJ3-1", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1MJJ3-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0AAA9S9M3", "url": "https://www.uniprot.org/uniprotkb/A0AAA9S9M3", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0AAA9S9M3-1", "url": "https://www.uniprot.org/uniprotkb/A0AAA9S9M3-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0AAA9SE31", "url": "https://www.uniprot.org/uniprotkb/A0AAA9SE31", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0AAA9SE31-1", "url": "https://www.uniprot.org/uniprotkb/A0AAA9SE31-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0AAA9TPZ9", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TPZ9", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0AAA9TPZ9-1", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TPZ9-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "F1N3Y8", "url": "https://www.uniprot.org/uniprotkb/F1N3Y8", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "F1N3Y8-1", "url": "https://www.uniprot.org/uniprotkb/F1N3Y8-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MEALEAETARAEDAEPAAPWARLEAPGRLLLQALQAGPDGARRGLGVLRTLSGRGGEPFAWGGVLEALCREEPVVEGPDCRLELKPLLLRLPPLCRRNLMSLLMAVWPSLPESRLLPVLQVARQDPSPDPDPWLQALGEFLQRDLSAGVSTDGASPLSERCQRQLQGLCRRLGQGGRKLKLPPTPDSEGEGGQEEDKDSQQPGKRRKEPEEKPVSPEGERAPKRLRCLEKEGHEDKRPEHESLESLADGGGASSITNQAVMGPEPSEAGQSLKDAKGLPESLELPKVIQDQVPRLQQLLKTLGKGLEGLEGTPPVELQLLQECSPGQVDLLCAQLQLPQLLDTGLLQLCTWLLALSPDLSLGNATVLTRSLFLGRIVSLTSSASRLLTTALTSFCTKYPYAVCRALLGPVLQAPGIGPAQTELLCCLTKDKALEPDVQVLMLGQILELPWKEETFLVLQSLLERQVEMPPEKFSVLMEKLCKEGPVATTSMAYAKLLLTVMTKYQANITEPQRLGLAAAVELNTTFLRKSLQAALRHLTP", "length": 540, "header": "tr|F1N3Y8-1|F1N3Y8_BOVIN Isoform 1 of FA complementation group E OS=Bos taurus OX=9913 GN=FANCE PE=4 SV=2 CANONICAL=F1N3Y8-1" }, "isoforms": [ { "isoform_ac": "A0A3Q1MJJ3-1", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1MJJ3/entry", "sequence": { "sequence": "MEALEAETARAEDAEPAAPWARLEAPGRLLLQALQAGPDGARRGLGVLRTLSGRGGEPFAWGGVLEALCREEPVVEGPDCRLELKPLLLRLPPLCRRNLMSLLMAVWPSLPESRLLPVLQVARQDPSPDPDPWLQALGEFLQRDLSAGVSTDGASPLSERCQRQLQGLCRRLGQGGRKLKLPPTPDSEGEGGQEEDKDSQQPGKRRKEPEEKPVSPEGERAPKRLRCLEKEGHEDKRPEHESLESLADGGGASSITNQAVMGPEPSEAGQSLKDAKGLPESLELPKVIQDQVPRLQQLLKTLGKVDLLCAQLQLPQLLDTGLLQLCTWLLALSPDLSLGNATVLTRSLFLGRIVSLTSSASRLLTTALTSFCTKYPYAVCRALLGPVLQAPGIGPAQTELLCCLTKDKALEPDVQVLMLGQILELPWKEETFLVLQSLLERQVEMPPEKFSVLMEKLCKEGPVATTSMAYAKLLLTVMTKYQANITEPQRLGLAAAVELNTTFLRKSLQAALRHLTP", "length": 517, "header": "tr|A0A3Q1MJJ3-1|F1N3Y8_BOVIN Computationally mapped isoform of FA complementation group E OS=Bos taurus OX=9913 GN=FANCE PE=4 SV=1 CANONICAL=F1N3Y8-1" }, "locus": { "chromosome": "23", "start_pos": 9424619, "end_pos": 9416113, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000081051.2", "url": "https://www.ensembl.org/id/ENSBTAT00000081051.2" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000070957.1", "url": "https://www.ensembl.org/id/ENSBTAP00000070957.1" } ] } }, { "isoform_ac": "A0AAA9S9M3-1", "url": "https://www.uniprot.org/uniprotkb/A0AAA9S9M3/entry", "sequence": { "sequence": "MEALEAETARAEDAEPAAPWARLEAPGRLLLQALQAGPDGARRGLGVLRTLSGRGGEPFAWGGVLEALCREEPVVEGPDCRLELKPLLLRLPPLCRRNLMSLLMAVWPSLPESRLLPVLQVARQDPSPDPDPWLQALGEFLQRDLSAGVSTDGASPLSERCQRQLQGLCRRLGQGGRKLKLPPTPDSEGEGGQEEDKDSQQPGKRRKEPEEKPVSPEGERAPKRLRCLEKEGHEDKRPEHESLESLADGGGASSITNQAVMGPEPSEAGQSLKDAKGLPESLELPKVIQDQVPRLQQLLKTLGKGLEGLEGTPPVELQLLQECSPGQVDLLCAQLQLPQLLDTGLLQLCTWLLALSPDLSLGNATVLTRSLFLGRIVSLTSSASRLLTTALTSFCTKYPYAVCRALLGPVLQAPGIGPAQTELLCCLTKDKALEPDVQVLMLGQILELPWKEETFLVLQSLLERQITEPQRLGLAAAVELNTTFLRKSLQAALRHLTP", "length": 498, "header": "tr|A0AAA9S9M3-1|F1N3Y8_BOVIN Computationally mapped isoform of FA complementation group E OS=Bos taurus OX=9913 GN=FANCE PE=4 SV=1 CANONICAL=F1N3Y8-1" }, "locus": { "chromosome": "23", "start_pos": 9424619, "end_pos": 9416113, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000122043.1", "url": "https://www.ensembl.org/id/ENSBTAT00000122043.1" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000082782.1", "url": "https://www.ensembl.org/id/ENSBTAP00000082782.1" } ] } }, { "isoform_ac": "A0AAA9SE31-1", "url": "https://www.uniprot.org/uniprotkb/A0AAA9SE31/entry", "sequence": { "sequence": "MEALEAETARAEDAEPAAPWARLEAPGRLLLQALQAGPDGARRGLGVLRTLSGRGGEPFAWGGVLEALCREEPVVEGPDCRLELKPLLLRLPPLCRRNLMSLLMAVWPSLPESRLLPVLQVARQDPSPDPDPWLQALGEFLQRDLSAGVSTDGASPLSERCQRQLQGLCRRLGQGGRKLKLPPTPDSEGEGGQEEDKDSQQPGKRRKEPEEKPVSPEGERAPKRLRCLEKEGHEDKRPEHESLESLADGGGASSITNQAVMGPEPSEAGQSLKDAKGLPESLELPKVIQDQVPRLQQLLKTLGKGLEGLEGTPPVELQLLQECSPGQVDLLCAQLQLPQLLDTGLLQLCTWLLALSPDLSLGNATVLTRSLFLGRIVSLTSSASRLLTTALTSFCTKYPYAVCRALLGPVLQAPGIGPAQTELLCCLTKDKALEPDVQVLMLGSLSPRGWAWLQLW", "length": 456, "header": "tr|A0AAA9SE31-1|F1N3Y8_BOVIN Computationally mapped isoform of FA complementation group E OS=Bos taurus OX=9913 GN=FANCE PE=4 SV=1 CANONICAL=F1N3Y8-1" }, "locus": { "chromosome": "23", "start_pos": 9424560, "end_pos": 9416113, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000130011.1", "url": "https://www.ensembl.org/id/ENSBTAT00000130011.1" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000084393.1", "url": "https://www.ensembl.org/id/ENSBTAP00000084393.1" } ] } }, { "isoform_ac": "A0AAA9TPZ9-1", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TPZ9/entry", "sequence": { "sequence": "MEALEAETARAEDAEPAAPWARLEAPGRLLLQALQAGPDGARRGLGVLRTLSGRGGEPFAWGGVLEALCREEPVVEGPDCRLELKPLLLRLPPLCRRNLMSLLMAVWPSLPESRLLPVLQVARQDPSPDPDPWLQALGEFLQRDLSAGVSTDGASPLSERCQRQLQGLCRRLGQGGRKLKLPPTPDSEGEGGQEEDKDSQQPGKRRKEPEEKPVSPEGERAPKRLRCLEKEGHEDKRPEHESLESLADGGGASSITNQAVMGPEPSEAGQSLKDAKGLPESLELPKVIQDQVPRLQQLLKTLGKGLEGLEGTPPVELQLLQECSPGQVDLLCAQLQLPQLLDTGLLQLCTWLLALSPDLSLGNATVLTRSLFLGRIVSLTSSASRLLTTALTSFCTKYPYAVCRALLGPVLQAPGIGPAQTELLCCLTKDKALEPDVQVLMLGQILELPWKEETFLVLQSLLERQVVTHQALSCNTECPVLCFFHLTGILAVFPYTGGDAP", "length": 501, "header": "tr|A0AAA9TPZ9-1|F1N3Y8_BOVIN Computationally mapped isoform of FA complementation group E OS=Bos taurus OX=9913 GN=FANCE PE=4 SV=1 CANONICAL=F1N3Y8-1" }, "locus": { "chromosome": "23", "start_pos": 9423311, "end_pos": 9416113, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000121014.1", "url": "https://www.ensembl.org/id/ENSBTAT00000121014.1" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000099364.1", "url": "https://www.ensembl.org/id/ENSBTAP00000099364.1" } ] } }, { "isoform_ac": "F1N3Y8-1", "url": "https://www.uniprot.org/uniprotkb/F1N3Y8/entry", "sequence": { "sequence": "MEALEAETARAEDAEPAAPWARLEAPGRLLLQALQAGPDGARRGLGVLRTLSGRGGEPFAWGGVLEALCREEPVVEGPDCRLELKPLLLRLPPLCRRNLMSLLMAVWPSLPESRLLPVLQVARQDPSPDPDPWLQALGEFLQRDLSAGVSTDGASPLSERCQRQLQGLCRRLGQGGRKLKLPPTPDSEGEGGQEEDKDSQQPGKRRKEPEEKPVSPEGERAPKRLRCLEKEGHEDKRPEHESLESLADGGGASSITNQAVMGPEPSEAGQSLKDAKGLPESLELPKVIQDQVPRLQQLLKTLGKGLEGLEGTPPVELQLLQECSPGQVDLLCAQLQLPQLLDTGLLQLCTWLLALSPDLSLGNATVLTRSLFLGRIVSLTSSASRLLTTALTSFCTKYPYAVCRALLGPVLQAPGIGPAQTELLCCLTKDKALEPDVQVLMLGQILELPWKEETFLVLQSLLERQVEMPPEKFSVLMEKLCKEGPVATTSMAYAKLLLTVMTKYQANITEPQRLGLAAAVELNTTFLRKSLQAALRHLTP", "length": 540, "header": "tr|F1N3Y8-1|F1N3Y8_BOVIN Isoform 1 of FA complementation group E OS=Bos taurus OX=9913 GN=FANCE PE=4 SV=2 CANONICAL=F1N3Y8-1" }, "locus": { "chromosome": "23", "start_pos": 9424619, "end_pos": 9416113, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000038911.6", "url": "https://www.ensembl.org/id/ENSBTAT00000038911.6" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000038717.4", "url": "https://www.ensembl.org/id/ENSBTAP00000038717.4" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [ { "id": "bta:513464", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?bta:513464", "resource": "KEGG Pathway" }, { "id": "R-BTA-6783310", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-BTA-6783310", "resource": "Reactome", "description": "Fanconi Anemia Pathway" }, { "id": "R-BTA-9833482", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-BTA-9833482", "resource": "Reactome", "description": "PKR-mediated signaling" } ], "orthologs": [ { "uniprot_canonical_ac": "B8JJD3-1", "protein_name": "Fanconi anemia, complementation group E", "gene_name": "Fance", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MATPGSDSVASAGAAPWASLEAPARLLLQALQAGPEGARRGLGVLRALGRRAEHFPWDGFLEALGHLEPEVRGPDGRLELVPLLLRLPGVCQKNLLSLLLALLPSLPESGLRSVLQLHHQDVSSTTDAWLHALGELLRRDVGVGVAEGSSPLTRSCQLQLRDLCGRLGQGGRGLKLALAPDPEQEDRLSQLCGKRTKEPEEAASPESERSPKRFRGCEEAVEGKEPEERPTLESLGSPPDAGGVLPDTDAQAPETGPGVEGPKGPAESVELPKVVQDQVPRLQLLLKAFQEGLEGQEKPLVDLQFLHECSPSEMELLCSELQLPQLPDGGLLQLCSHLMGLTPALSLSNASVLARSLFLDRIRSLPSSASRLLRVALVSFCVKYTYAICRAVLCPLLQDPRVGPAQTELLCSLIKDESLESDMQVQILGQVLELAWREETFLVLQTLLERQVEMTPEVFSVLVQRLCKEGPAATTSMAYAKLMLTVMTKYQTSITEQQSLDLAVALEPNATFLKKALQAALRHVTH", "length": 526 }, "evidence": [ { "id": "F1N3Y8", "url": "https://omabrowser.org/oma/group/F1N3Y8/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "F1M286-1", "protein_name": "FA complementation group E", "gene_name": "Fance", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "GALRPRVSCPPPRLGSPLARPVSDAVASARATPWATLEAPARLLLQALQAGPEGARRGLGVLRTLGRRAEHFPWDSFLEALGRAEPEVRGPDGRLELTPLLLRLPGVCRKNLMSLLLAVRSSLPESGLRSVLQLDQQGTASTSDAWLHALRELLQRDVGLGVSVEGSSPLTGSCQSHLRDLCGRLGQGGRGLKPALGSDPEPEGRLSQLSGKRRKRTEGETAGPELERSPKRFRGCEEEQEEVVERKEERPKPETSESESDAGGVLPDTEVEAPEARPGVAEAESPAKSVELPKVVQDQVPRLRQLLKALQEGLEGLEEPPVDLQFLHECSPSQMESLCSQLQLPQLPDGGLLQLCSHLLGLTPALSISNASVLARSLFLDRILSLPSSASRLLRAALTSFCAKYTYAVCRAVLCPLFQDPGIGPVQTELLCSLLKDESLEPDMQVQILGQVLELAWREETFLVLQALLERQVEMTSELFSVLMQRLCKEGPAATTSMAYAKLMLTVMTKYQASISQQQSLDLAVALEPNTTFLKKSLQAALRHLAR", "length": 547 }, "evidence": [ { "id": "F1N3Y8", "url": "https://omabrowser.org/oma/group/F1N3Y8/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "Q9HB96-1", "protein_name": "Fanconi anemia group E protein", "gene_name": "FANCE", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MATPDAGLPGAEGVEPAPWAQLEAPARLLLQALQAGPEGARRGLGVLRALGSRGWEPFDWGRLLEALCREEPVVQGPDGRLELKPLLLRLPRICQRNLMSLLMAVRPSLPESGLLSVLQIAQQDLAPDPDAWLRALGELLRRDLGVGTSMEGASPLSERCQRQLQSLCRGLGLGGRRLKSPQAPDPEEEENRDSQQPGKRRKDSEEEAASPEGKRVPKRLRCWEEEEDHEKERPEHKSLESLADGGSASPIKDQPVMAVKTGEDGSNLDDAKGLAESLELPKAIQDQLPRLQQLLKTLEEGLEGLEDAPPVELQLLHECSPSQMDLLCAQLQLPQLSDLGLLRLCTWLLALSPDLSLSNATVLTRSLFLGRILSLTSSASRLLTTALTSFCAKYTYPVCSALLDPVLQAPGTGPAQTELLCCLVKMESLEPDAQVLMLGQILELPWKEETFLVLQSLLERQVEMTPEKFSVLMEKLCKKGLAATTSMAYAKLMLTVMTKYQANITETQRLGLAMALEPNTTFLRKSLKAALKHLGP", "length": 536 }, "evidence": [ { "id": "F1N3Y8", "url": "https://omabrowser.org/oma/group/F1N3Y8/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" } ], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 3, "go_terms": [ { "name": "Fanconi anaemia nuclear complex", "id": "GO:0043240", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0043240", "evidence": [ { "database": "UniProtKB", "id": "F1N3Y8", "url": "https://www.uniprot.org/uniprotkb/F1N3Y8" } ], "pmid": "" }, { "name": "nucleoplasm", "id": "GO:0005654", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005654", "evidence": [ { "database": "UniProtKB", "id": "F1N3Y8", "url": "https://www.uniprot.org/uniprotkb/F1N3Y8" } ], "pmid": "" }, { "name": "chromatin", "id": "GO:0000785", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000785", "evidence": [ { "database": "UniProtKB", "id": "F1N3Y8", "url": "https://www.uniprot.org/uniprotkb/F1N3Y8" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 1, "go_terms": [ { "name": "interstrand cross-link repair", "id": "GO:0036297", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0036297", "evidence": [ { "database": "UniProtKB", "id": "F1N3Y8", "url": "https://www.uniprot.org/uniprotkb/F1N3Y8" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 363, "end_pos": 365, "annotation": "n_glycosylation_sequon" }, { "start_pos": 507, "end_pos": 509, "annotation": "n_glycosylation_sequon" }, { "start_pos": 523, "end_pos": 525, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [ { "pdb_id": "AF-F1N3Y8-F1", "pdb_chain": "global", "start_pos": 1, "end_pos": 540, "overlap": "1.0", "method": "AlphaFold", "type": "alphafold", "resolution": -1.0, "url": "https://data.glygen.org/ln2downloads/pdb/current/AF-F1N3Y8-F1.pdb", "url_external": "https://alphafold.ebi.ac.uk/entry/F1N3Y8" } ], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "F1N3Y8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1N3Y8" }, { "id": "PF11510", "database": "Pfam", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF11510" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "Fanconi Anaemia group E protein C-terminal", "eco_id": "ECO_0000259", "start_pos": 278, "end_pos": 538, "start_aa": "Leu", "end_aa": "Leu", "glycosite_overlap": [] } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" }, { "name": "homologset.oma", "label": "OMA Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 363, "end_pos": 365 }, { "start_pos": 507, "end_pos": 509 }, { "start_pos": 523, "end_pos": 525 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": 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"total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ], "tool_support": { "graph_view": "yes" } }, { "uniprot_canonical_ac": "F6QF30-1", "uniprot_ac": "F6QF30", "uniprot_id": "F6QF30_BOVIN", "mass": { "chemical_mass": 55875.0, "monoisotopic_mass": 55875.0 }, "refseq": {}, "gene_names": [ { "name": "DUS2", "type": "recommended", "evidence": [ { "id": "F6QF30", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F6QF30" } ] } ], "protein_names": [ { "name": "tRNA-dihydrouridine(20) synthase [NAD(P)+]-like", "type": "recommended", "evidence": [ { "id": "F6QF30", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F6QF30/entry#names_and_taxonomy" } ] }, { "name": "1.3.1.91", "type": "synonym", "evidence": [ { "id": "F6QF30", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F6QF30/entry#names_and_taxonomy" } ] }, { "name": "Dihydrouridine synthase 2", "type": "synonym", "evidence": [ { "id": "F6QF30", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F6QF30/entry#names_and_taxonomy" } ] }, { "name": "tRNA-dihydrouridine synthase 2-like", "type": "synonym", "evidence": [ { "id": "F6QF30", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F6QF30/entry#names_and_taxonomy" } ] } ], "function": [ { "annotation": "Catalyzes the NADPH-dependent synthesis of dihydrouridine, a modified base found in the D-loop of most tRNAs. Specifically modifies U20 in cytoplasmic tRNAs. Activity depends on the presence of guanosine at position 19 in the tRNA substrate. Negatively regulates the activation of EIF2AK2/PKR.", "evidence": [ { "database": "UniProtKB", "id": "A0A3Q1MLP6", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1MLP6#function" }, { "database": "UniProtKB", "id": "ARBA00054045", "url": "https://www.uniprot.org/uniprotkb/ARBA00054045#function" }, { "database": "UniProtKB", "id": "F6QF30", "url": "https://www.uniprot.org/uniprotkb/F6QF30#function" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Bos taurus", "taxid": 9913, "evidence": [ { "database": "UniProtKB", "id": "F6QF30", "url": "https://www.uniprot.org/uniprotkb/F6QF30" } ], "common_name": "Bovine", "glygen_name": "Bovine", "reference_species": "Bos taurus [9913]" } ], "gene": [ { "name": "DUS2", "url": "https://www.uniprot.org/uniprotkb/F6QF30", "locus": { "chromosome": "18", "start_pos": 35513050, "end_pos": 35480003, "strand": "-", "evidence": [ { "database": "Ensembl Gene", "id": "ENSBTAG00000014644", "url": "https://www.ensembl.org/id/ENSBTAG00000014644" } ] } } ], "crossref": [ { "id": "F6QF30", "url": "https://alphafold.ebi.ac.uk/entry/F6QF30", "database": "AlphaFoldDB", "categories": [] }, { "id": "ENSBTAG00000014644", "url": "https://bgee.org/?page=gene&gene_id=ENSBTAG00000014644", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "cd02801", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd02801", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "cd19871", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd19871", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "IPR013785", "url": "https://www.ebi.ac.uk/interpro/entry/IPR013785", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR014720", "url": "https://www.ebi.ac.uk/interpro/entry/IPR014720", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR018517", "url": "https://www.ebi.ac.uk/interpro/entry/IPR018517", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR035587", "url": "https://www.ebi.ac.uk/interpro/entry/IPR035587", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR044463", "url": "https://www.ebi.ac.uk/interpro/entry/IPR044463", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR052582", "url": "https://www.ebi.ac.uk/interpro/entry/IPR052582", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "PTHR45936", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR45936", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR45936:SF1", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR45936:SF1", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00035", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00035", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF01207", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF01207", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "53336", "url": "https://www.rhea-db.org/rhea/53336", "database": "Rhea", "categories": [ "Enzyme and Pathway" ] }, { "id": "A0A3Q1MLP6", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1MLP6", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A3Q1MLP6-1", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1MLP6-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A3Q1MXX8", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1MXX8", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A3Q1MXX8-1", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1MXX8-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "F6QF30", "url": "https://www.uniprot.org/uniprotkb/F6QF30", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "F6QF30-1", "url": "https://www.uniprot.org/uniprotkb/F6QF30-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MTVNNLSLCYHNKLILAPMVRVGTLPMRLLALDYGADIVYCEELVDLKMLQCKRVVNEALSTVDFVAPDDRVVFRTCEREQSKVVFQMGTSDAERALAVARLVENDVAGIDVNMGCPKEYSTKGGMGAALLSDPDKIEKILSTLVKGTRRPVTCKIRILPSLEDTLSLVKRIERTGIAAIAVHGSPISLSPRKREERPQHPVSCEAIKAIAETLSIPVIANGGSHDHIQGYLDIEDFRRATAASSVMVARAAMWNPSIFLKEGPRPLEEVMQKYIRYAVQYDNHYTNTKYCLCQMLREQLESPQGRLLHAAQSSQEICEAFGLGAFYEETTRELDARRAKLLARSPEEAEEPAEDTSGIIKMAIKFDRRAYSPQITPKMCLLEWCRREKLAQPVYETVQRPLDRLFCSVVTVAEQKYQSTLWDKSKKLAEQAAAIVCLRSQGLPEGRLGEESPSLHKRKREALDQDPGDPRTQEPAMPGELCKKPFVALASGQESPLEGW", "length": 500, "header": "tr|F6QF30-1|F6QF30_BOVIN Isoform 1 of tRNA-dihydrouridine(20) synthase [NAD(P)+]-like OS=Bos taurus OX=9913 GN=DUS2 PE=3 SV=1 CANONICAL=F6QF30-1" }, "isoforms": [ { "isoform_ac": "A0A3Q1MLP6-1", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1MLP6/entry", "sequence": { "sequence": "MTVNNLSLCYHNKLILAPMVRVGTLPMRLLALDYGADIVYCEELVDLKMLQCKRVVNEALSTVDFVAPDDRVVFRTCEREQSKVVFQMGTSDAERALAVARLVENDVAGIDVNMGCPKEYSTKGGMGAALLSDPDKIEKILSTLVKGTRRPVTCKIRILPSLEDTLSLVKRIERTGIAAIAVHGRKREERPQHPVSCEAIKAIAETLSIPVIANGGSHDHIQGYLDIEDFRRATAASSVMVARAAMWNPSIFLKEGPRPLEEVMQKYIRYAVQYDNHYTNTKYCLCQMLREQLESPQGRLLHAAQSSQEICEAFGLGAFYEETTRELDARRAKLLARSPEEAEEPAEDTSGIIKMAIKFDRRAYSPQITPKMCLLEWCRREKLAQPVYETVQRPLDRLFCSVVTVAEQKYQSTLWDKSKKLAEQAAAIVCLRSQGLPEGRLDKDTTKPGPPGAHHSLTLGESLLVLAGPKSPSLSGISCSTA", "length": 482, "header": "tr|A0A3Q1MLP6-1|F6QF30_BOVIN Computationally mapped isoform of tRNA-dihydrouridine(20) synthase [NAD(P)+]-like OS=Bos taurus OX=9913 GN=DUS2 PE=3 SV=2 CANONICAL=F6QF30-1" }, "locus": { "chromosome": "18", "start_pos": 35512990, "end_pos": 35484046, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000087071.3", "url": "https://www.ensembl.org/id/ENSBTAT00000087071.3" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000070250.2", "url": "https://www.ensembl.org/id/ENSBTAP00000070250.2" } ] } }, { "isoform_ac": "A0A3Q1MXX8-1", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1MXX8/entry", "sequence": { "sequence": "MTVNNLSLCYHNKLILAPMVRVGTLPMRLLALDYGADIVYCEELVDLKMLQCKRVVNEALSTVDFVAPDDRVVFRTCEREQSKVVFQMGGMGAALLSDPDKIEKILSTLVKGTRRPVTCKIRILPSLEDTLSLVKRIERTGIAAIAVHGRKREERPQHPVSCEAIKAIAETLSIPVIANGGSHDHIQGYLDIEDFRRATAASSVMVARAAMWNPSIFLKEGPRPLEEVMQKYIRYAVQYDNHYTNTKYCLCQMLREQLESPQGRLLHAAQSSQEICEAFGLGAFYEETTRELDARRAKLLARSPEEAEEPAEDTSGIIKMAIKFDRRAYSPQITPKMCLLEWCRREKLAQPVYETVQRPLDRLFCSVVTVAEQKYQSTLWDKSKKLAEQAAAIVCLRSQGLPEGRLGEESPSLHKRKREALDQDPGDPRTQEPAMPGELCKKPFVALASGQESPLEGW", "length": 458, "header": "tr|A0A3Q1MXX8-1|F6QF30_BOVIN Computationally mapped isoform of tRNA-dihydrouridine(20) synthase [NAD(P)+]-like OS=Bos taurus OX=9913 GN=DUS2 PE=3 SV=1 CANONICAL=F6QF30-1" }, "locus": { "chromosome": "18", "start_pos": 35511692, "end_pos": 35484046, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000070072.3", "url": "https://www.ensembl.org/id/ENSBTAT00000070072.3" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000060735.1", "url": "https://www.ensembl.org/id/ENSBTAP00000060735.1" } ] } }, { "isoform_ac": "F6QF30-1", "url": "https://www.uniprot.org/uniprotkb/F6QF30/entry", "sequence": { "sequence": "MTVNNLSLCYHNKLILAPMVRVGTLPMRLLALDYGADIVYCEELVDLKMLQCKRVVNEALSTVDFVAPDDRVVFRTCEREQSKVVFQMGTSDAERALAVARLVENDVAGIDVNMGCPKEYSTKGGMGAALLSDPDKIEKILSTLVKGTRRPVTCKIRILPSLEDTLSLVKRIERTGIAAIAVHGSPISLSPRKREERPQHPVSCEAIKAIAETLSIPVIANGGSHDHIQGYLDIEDFRRATAASSVMVARAAMWNPSIFLKEGPRPLEEVMQKYIRYAVQYDNHYTNTKYCLCQMLREQLESPQGRLLHAAQSSQEICEAFGLGAFYEETTRELDARRAKLLARSPEEAEEPAEDTSGIIKMAIKFDRRAYSPQITPKMCLLEWCRREKLAQPVYETVQRPLDRLFCSVVTVAEQKYQSTLWDKSKKLAEQAAAIVCLRSQGLPEGRLGEESPSLHKRKREALDQDPGDPRTQEPAMPGELCKKPFVALASGQESPLEGW", "length": 500, "header": "tr|F6QF30-1|F6QF30_BOVIN Isoform 1 of tRNA-dihydrouridine(20) synthase [NAD(P)+]-like OS=Bos taurus OX=9913 GN=DUS2 PE=3 SV=1 CANONICAL=F6QF30-1" }, "locus": { "chromosome": "18", "start_pos": 35511692, "end_pos": 35484046, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000019500.6", "url": "https://www.ensembl.org/id/ENSBTAT00000019500.6" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000019500.4", "url": "https://www.ensembl.org/id/ENSBTAP00000019500.4" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [ "enzyme" ], "publication": [], "pathway": [], "orthologs": [], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 2, "go_terms": [ { "name": "endoplasmic reticulum", "id": "GO:0005783", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005783", "evidence": [ { "database": "UniProtKB", "id": "F6QF30", "url": "https://www.uniprot.org/uniprotkb/F6QF30" } ], "pmid": "" }, { "name": "cytosol", "id": "GO:0005829", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005829", "evidence": [ { "database": "UniProtKB", "id": "F6QF30", "url": "https://www.uniprot.org/uniprotkb/F6QF30" } ], "pmid": "" } ] }, { "name": "Molecular Function", "total": 7, "go_terms": [ { "name": "flavin adenine dinucleotide binding", "id": "GO:0050660", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0050660", "evidence": [ { "database": "UniProtKB", "id": "F6QF30", "url": "https://www.uniprot.org/uniprotkb/F6QF30" } ], "pmid": "" }, { "name": "tRNA binding", "id": "GO:0000049", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000049", "evidence": [ { "database": "UniProtKB", "id": "F6QF30", "url": "https://www.uniprot.org/uniprotkb/F6QF30" } ], "pmid": "" }, { "name": "tRNA-dihydrouridine20 synthase activity", "id": "GO:0102264", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0102264", "evidence": [ { "database": "UniProtKB", "id": "F6QF30", "url": "https://www.uniprot.org/uniprotkb/F6QF30" } ], "pmid": "" }, { "name": "protein kinase inhibitor activity", "id": "GO:0004860", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0004860", "evidence": [ { "database": "UniProtKB", "id": "F6QF30", "url": "https://www.uniprot.org/uniprotkb/F6QF30" } ], "pmid": "" }, { "name": "double-stranded RNA binding", "id": "GO:0003725", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003725", "evidence": [ { "database": "UniProtKB", "id": "F6QF30", "url": "https://www.uniprot.org/uniprotkb/F6QF30" } ], "pmid": "" }, { "name": "NADPH binding", "id": "GO:0070402", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0070402", "evidence": [ { "database": "UniProtKB", "id": "F6QF30", "url": "https://www.uniprot.org/uniprotkb/F6QF30" } ], "pmid": "" }, { "name": "FMN binding", "id": "GO:0010181", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0010181", "evidence": [ { "database": "UniProtKB", "id": "F6QF30", "url": "https://www.uniprot.org/uniprotkb/F6QF30" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 1, "go_terms": [ { "name": "antiviral innate immune response", "id": "GO:0140374", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0140374", "evidence": [ { "database": "UniProtKB", "id": "F6QF30", "url": "https://www.uniprot.org/uniprotkb/F6QF30" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 5, "end_pos": 7, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [ { "id": "53336", "name": "", "equation": "5,6-dihydrouridine(20) in tRNA + NADP(+) = uridine(20) in tRNA + NADPH + H(+)", "summary": "", "cellular_location": "", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [ "F6QF30-1" ], "evidence": [ { "id": "53336", "database": "Rhea", "url": "https://www.rhea-db.org/rhea/53336" } ] } ], "reaction_participants": [], "reaction_enzymes": [ { "uniprot_ac": "F6QF30", "gene_name": "DUS2", "activity": [ { "ec_number": "1.3.1.91", "activity": "5,6-dihydrouridine(20) in tRNA + NAD(+) = uridine(20) in tRNA + NADH + H(+).", "evidence": [ { "id": "F6QF30", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F6QF30" } ] }, { "ec_number": "1.3.1.91", "activity": "", "evidence": [ { "id": "F6QF30", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F6QF30" } ] } ] } ], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "F6QF30", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F6QF30" }, { "id": "SM00358", "database": "SMART", "url": "http://smart.embl.de/smart/do_annotation.pl?DOMAIN=SM00358" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "DRBM", "eco_id": "ECO_0000259", "start_pos": 377, "end_pos": 442, "start_aa": "Pro", "end_aa": "Gly", "glycosite_overlap": [] } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [ { "ec_number": "1.3.1.91", "ec_name": "5,6-dihydrouridine(20) in tRNA + NAD(+) = uridine(20) in tRNA + NADH + H(+).", "evidence": [ { "id": "1.3.1.91", "database": "Rhea", "url": "https://www.rhea-db.org/rhea/?query=ec:1.3.1.91" }, { "id": "1.3.1.91", "database": "BRENDA Enzymes", "url": "https://www.brenda-enzymes.org/enzyme.php?ecno=1.3.1.91" } ] } ], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 5, "end_pos": 7 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ], "tool_support": { "graph_view": "yes" } }, { "uniprot_canonical_ac": "F6RCR6-1", "uniprot_ac": "F6RCR6", "uniprot_id": "F6RCR6_BOVIN", "mass": { "chemical_mass": 52772.0, "monoisotopic_mass": 52772.0 }, "refseq": { "ac": "XP_005220173", "name": "coronin-6 isoform X1", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_005220173" }, "gene_names": [ { "name": "CORO6", "type": "recommended", "evidence": [ { "id": "F6RCR6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F6RCR6" } ] }, { "name": "CORO6", "type": "synonym", "evidence": [ { "id": "XP_005220173", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_005220173" } ] } ], "protein_names": [ { "name": "Coronin", "type": "recommended", "evidence": [ { "id": "F6RCR6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F6RCR6/entry#names_and_taxonomy" } ] }, { "name": "coronin-6 isoform X1", "type": "synonym", "evidence": [ { "id": "XP_005220173", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_005220173" } ] } ], "function": [], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Bos taurus", "taxid": 9913, "evidence": [ { "database": "UniProtKB", "id": "F6RCR6", "url": "https://www.uniprot.org/uniprotkb/F6RCR6" } ], "common_name": "Bovine", "glygen_name": "Bovine", "reference_species": "Bos taurus [9913]" } ], "gene": [ { "name": "CORO6", "url": "https://www.uniprot.org/uniprotkb/F6RCR6", "locus": { "chromosome": "19", "start_pos": 20865347, "end_pos": 20873587, "strand": "+", "evidence": [ { "database": "Ensembl Gene", "id": "ENSBTAG00000001120", "url": "https://www.ensembl.org/id/ENSBTAG00000001120" } ] } } ], "crossref": [ { "id": "F6RCR6", "url": "https://alphafold.ebi.ac.uk/entry/F6RCR6", "database": "AlphaFoldDB", "categories": [] }, { "id": "ENSBTAG00000001120", "url": "https://bgee.org/?page=gene&gene_id=ENSBTAG00000001120", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "614661", "url": "https://www.ncbi.nlm.nih.gov/gene/614661", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR001680", "url": "https://www.ebi.ac.uk/interpro/entry/IPR001680", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR015048", "url": "https://www.ebi.ac.uk/interpro/entry/IPR015048", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR015505", "url": "https://www.ebi.ac.uk/interpro/entry/IPR015505", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR015943", "url": "https://www.ebi.ac.uk/interpro/entry/IPR015943", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR019775", "url": "https://www.ebi.ac.uk/interpro/entry/IPR019775", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR036322", "url": "https://www.ebi.ac.uk/interpro/entry/IPR036322", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "YPPILMH", "url": "https://omabrowser.org/oma/group/YPPILMH/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "A0A3Q1LG34", "url": "https://www.orthodb.org/?gene=A0A3Q1LG34", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A3Q1MMX8", "url": "https://www.orthodb.org/?gene=A0A3Q1MMX8", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR10856", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR10856", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR10856:SF23", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR10856:SF23", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00400", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00400", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF08953", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF08953", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF16300", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF16300", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "XP_005220173", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_005220173", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A3Q1LG34", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1LG34", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A3Q1LG34-1", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1LG34-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A3Q1MMX8", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1MMX8", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A3Q1MMX8-1", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1MMX8-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0AAA9TGK9", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TGK9", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0AAA9TGK9-1", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TGK9-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "F6RCR6", "url": "https://www.uniprot.org/uniprotkb/F6RCR6", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "F6RCR6-1", "url": "https://www.uniprot.org/uniprotkb/F6RCR6-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MSRRVVRQSKFRHVFGQAAKADQAYEDIRVSKVTWDSAFCAVNPKFLAIIVEAGGGGAFIVLPLAKTGRVDKNYPLVTGHTAPVLDIDWCPHNDNVIASASDDTTIMVWQIPDYTPVRSITEPIITLEGHSKRVGILSWHPTARNVLLSAGGDNVIIIWNVGTGEVLLSLDDMHPDVIHSVCWNTNGSLLATTCKDKTLRIIDPRKGQVVAERFAAHEGMRPMRAVFTRQGHIFTTGFTRMSQRELGLWDPNNFEEPVALQEMDTSNGVLLPFYDPDSSIVYLCGKGDSSIRYFEITEEPPFVHYLNTFSSKEPQRGMGFMPKRGLDVSKCEIARFYKLHERKCEPIVMTVPRKSDLFQDDLYPDTPGPEPALEADEWLSGQDADPVLISLRDGYVPPKHRELRVTKRNILDVRPPSGPRRSQSASNAPLSQHTLETLLEEIKALREQVQAQEQRITSLENMLCELVDGTD", "length": 471, "header": "tr|F6RCR6-1|F6RCR6_BOVIN Isoform 1 of Coronin OS=Bos taurus OX=9913 GN=CORO6 PE=3 SV=1 CANONICAL=F6RCR6-1" }, "isoforms": [ { "isoform_ac": "A0A3Q1LG34-1", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1LG34/entry", "sequence": { "sequence": "MSRRVVRQSKFRHVFGQAAKADQAYEDIRVSKVTWDSAFCAVNPKFLAIIVEAGGGGAFIVLPLAKTGRVDKNYPLVTGHTAPVLDIDWCPHNDNVIASASDDTTIMVWQIPDYTPVRSITEPIITLEGHSKRVGILSWHPTARNVLLSAGGDNVIIIWNVGTGEVLLSLDDMHPDVIHSVCWNTNGSLLATTCKDKTLRIIDPRKGQVVAERARPHEGARPLRAVFTTDGKLLSTGFSRMSERQLALWDPNNFEEPVALQEMDTSNGVLLPFYDPDSSIVYLCGKGDSSIRYFEITEEPPFVHYLNTFSSKEPQRGMGFMPKRGLDVSKCEIARFYKLHERKCEPIVMTVPRKSDLFQDDLYPDTPGPEPALEADEWLSGQDADPVLISLRDGYVPPKHRELRVTKRNILDVRPPSGPRRSQSASNAPLSQHTLETLLEEIKALREQVQAQEQRITSLENMLCELVDGTD", "length": 471, "header": "tr|A0A3Q1LG34-1|A0A3Q1LG34_BOVIN Computationally mapped isoform of Coronin OS=Bos taurus OX=9913 GN=CORO6 PE=3 SV=2 CANONICAL=F6RCR6-1" }, "locus": { "chromosome": "19", "start_pos": 20872133, "end_pos": 20866364, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000068823.2", "url": "https://www.ensembl.org/id/ENSBTAT00000068823.2" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000057299.2", "url": "https://www.ensembl.org/id/ENSBTAP00000057299.2" } ] } }, { "isoform_ac": "A0A3Q1MMX8-1", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1MMX8/entry", "sequence": { "sequence": "MSRRVVRQSKFRHVFGQAAKADQAYEDIRVSKVTWDSAFCAVNPKFLAIIVEAGGGGAFIVLPLAKTGRVDKNYPLVTGHTAPVLDIDWCPHNDNVIASASDDTTIMVWQIPDYTPVRSITEPIITLEGHSKRVGILSWHPTARNVLLSAGGDNVIIIWNVGTGEVLLSLDDMHPDVIHSVCWNTNGSLLATTCKDKTLRIIDPRKGQVVAERARPHEGARPLRAVFTTDGKLLSTGFSRMSERQLALWDPERFAAHEGMRPMRAVFTRQGHIFTTGFTRMSQRELGLWDPVTQLDAWVLLRRLKEPMLAPPPGDAESLGVVCGDCMRRHRGSRCGGPGVVSRGWVCSFVHQRCLGSARASGRAGSVQELRGIRKRHRGWAGAGCSRLLCLGRTTSRSQWRCRRWTQAMGSYCLSTIPTPASSTCAARATAAFGTLRSPRNLPSCTT", "length": 447, "header": "tr|A0A3Q1MMX8-1|F6RCR6_BOVIN Computationally mapped isoform of Coronin OS=Bos taurus OX=9913 GN=CORO6 PE=3 SV=2 CANONICAL=F6RCR6-1" }, "locus": { "chromosome": "19", "start_pos": 20872133, "end_pos": 20867414, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000069597.2", "url": "https://www.ensembl.org/id/ENSBTAT00000069597.2" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000070833.2", "url": "https://www.ensembl.org/id/ENSBTAP00000070833.2" } ] } }, { "isoform_ac": "A0AAA9TGK9-1", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TGK9/entry", "sequence": { "sequence": "MSRRVVRQSKFRHVFGQAAKADQAYEDIRVSKVTWDSAFCAVNPKFLAIIVEAGGGGAFIVLPLAKTGRVDKNYPLVTGHTAPVLDIDWCPHNDNVIASASDDTTIMVWQIPDYTPVRSITEPIITLEGHSKRVGILSWHPTARNVLLSAGGDNVIIIWNVGTGEVLLSLDDMHPDVIHSVCWNTNGSLLATTCKDKTLRIIDPRKGQVVANNFEEPVALQEMDTSNGVLLPFYDPDSSIVYLCGKGDSSIRYFEITEEPPFVHYLNTFSSKEPQRGMGFMPKRGLDVSKCEIARFYKLHERKCEPIVMTVPRKSDLFQDDLYPDTPGPEPALEADEWLSGQDADPVLISLRDGYVPPKHRELRVTKRNILDVRPPSGPRRSQSASNAPLSVRPRAAPPRPNLQPPTAPRPTPLRSSAPRSSTPWRRCWRRSRPCASRCRPRSSASRLWRTCCASWWTARTSAAPTGRSKPGSTVGRSASTPEGPGFGSRAPHSAPLGLGGDWGGNSALRGRSGQLQRLVSVCRPPGGVPRPGFRQELAGPQQWCCTAGSVPFVPHPGQRKCLVLAQCLEMVGSLGLTSKG", "length": 581, "header": "tr|A0AAA9TGK9-1|F6RCR6_BOVIN Computationally mapped isoform of Coronin OS=Bos taurus OX=9913 GN=CORO6 PE=3 SV=1 CANONICAL=F6RCR6-1" }, "locus": { "chromosome": "19", "start_pos": 20872133, "end_pos": 20866003, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000106474.1", "url": "https://www.ensembl.org/id/ENSBTAT00000106474.1" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000095325.1", "url": "https://www.ensembl.org/id/ENSBTAP00000095325.1" } ] } }, { "isoform_ac": "F6RCR6-1", "url": "https://www.uniprot.org/uniprotkb/F6RCR6/entry", "sequence": { "sequence": "MSRRVVRQSKFRHVFGQAAKADQAYEDIRVSKVTWDSAFCAVNPKFLAIIVEAGGGGAFIVLPLAKTGRVDKNYPLVTGHTAPVLDIDWCPHNDNVIASASDDTTIMVWQIPDYTPVRSITEPIITLEGHSKRVGILSWHPTARNVLLSAGGDNVIIIWNVGTGEVLLSLDDMHPDVIHSVCWNTNGSLLATTCKDKTLRIIDPRKGQVVAERFAAHEGMRPMRAVFTRQGHIFTTGFTRMSQRELGLWDPNNFEEPVALQEMDTSNGVLLPFYDPDSSIVYLCGKGDSSIRYFEITEEPPFVHYLNTFSSKEPQRGMGFMPKRGLDVSKCEIARFYKLHERKCEPIVMTVPRKSDLFQDDLYPDTPGPEPALEADEWLSGQDADPVLISLRDGYVPPKHRELRVTKRNILDVRPPSGPRRSQSASNAPLSQHTLETLLEEIKALREQVQAQEQRITSLENMLCELVDGTD", "length": 471, "header": "tr|F6RCR6-1|F6RCR6_BOVIN Isoform 1 of Coronin OS=Bos taurus OX=9913 GN=CORO6 PE=3 SV=1 CANONICAL=F6RCR6-1" }, "locus": { "chromosome": "19", "start_pos": 20872133, "end_pos": 20866364, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000001490.7", "url": "https://www.ensembl.org/id/ENSBTAT00000001490.7" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000001490.6", "url": "https://www.ensembl.org/id/ENSBTAP00000001490.6" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [], "orthologs": [ { "uniprot_canonical_ac": "A0A8V1APV1-1", "protein_name": "Coronin", "gene_name": "CORO6", "tax_id": 9031, "organism": "Gallus gallus", "sequence": { "sequence": "MSRRVVRQSKFRHVFGQPVKADQMYEDIRVSKVTWDSSFCAVNPKFLAIIVESGGGGAFMVLPLAKTGRVDKNHPLVTGHTAPVLDIDWCPHNDNVIASASEDTTVMVWQIPDYVPVRSITEPVVTLEGHSKRVGIICWHPTARNVLLSAGCDNLVILWNVGTGEMLLALEDMHTDLIYNVGWNRNGSLLVTTCKDKKVRVIDPRKQTVVAEITKPHDGARPIRAIFMADGKIFTTGFSKMSERQLGLWDLERFAPHEGLRPVRAIFTREGHIFTTGFTRMSQRELGLWDPKNFEEPIALQEMDTSNGVLLPFYDADSSIVYLCGKGDSSIRYFEITDEAPYVHYLNTYSSKEPQRGMGFMPKRGLDVSKCEIARFFKLHERKCEPIVMTVPRKSDLFQDDLYPDTPGPEPALEADEWLSGKDAEPILISLRDGYVPVKNRELKVVKKNILDSKPPPGPRRSHSTSNTDISTPALDEVLEEIRVLKETVQAQEKRISALEHKLCQFTNGTD", "length": 511 }, "evidence": [ { "id": "F6RCR6", "url": "https://omabrowser.org/oma/group/F6RCR6/", "database": "OMA" } ], "glygen_name": "Chicken", "common_name": "Chicken" }, { "uniprot_canonical_ac": "Q6QEF8-1", "protein_name": "Coronin-6", "gene_name": "CORO6", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MSRRVVRQSKFRHVFGQAAKADQAYEDIRVSKVTWDSSFCAVNPKFLAIIVEAGGGGAFIVLPLAKTGRVDKNYPLVTGHTAPVLDIDWCPHNDNVIASASDDTTIMVWQIPDYTPMRNITEPIITLEGHSKRVGILSWHPTARNVLLSAGGDNVIIIWNVGTGEVLLSLDDMHPDVIHSVCWNSNGSLLATTCKDKTLRIIDPRKGQVVAEQARPHEGARPLRAVFTADGKLLSTGFSRMSERQLALWDPNNFEEPVALQEMDTSNGVLLPFYDPDSSIVYLCGKGDSSIRYFEITDEPPFVHYLNTFSSKEPQRGMGFMPKRGLDVSKCEIARFYKLHERKCEPIIMTVPRKSDLFQDDLYPDTPGPEPALEADEWLSGQDAEPVLISLRDGYVPPKHRELRVTKRNILDVRPPSGPRRSQSASDAPLSQQHTLETLLEEIKALRERVQAQEQRITALENMLCELVDGTD", "length": 472 }, "evidence": [ { "id": "F6RCR6", "url": "https://omabrowser.org/oma/group/F6RCR6/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "Q920J3-1", "protein_name": "Coronin-6", "gene_name": "Coro6", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MSRRVVRQSKFRHVFGQAAKADQAYEDIRVSKVTWDSAFCAVNPKFLAIIVEAGGGGAFIVLPLAKTGRVDKNYPLVTGHTGPVLDIDWCPHNDNVIASASDDTTVMVWQIPDYTPVRNITEPVITLEGHSKRVGILSWHPTARNVLLSAGGDNVIIIWNVGTGEVLLSLDDIHPDVIHSVCWNSNGSLLATTCKDKTLRIIDPRKSQVVAERFAAHEGMRPMRAVFTRLGHIFTTGFTRMSQRELGLWDPNNFEEPVALQEMDTSNGVLLPFYDPDSSIVYLCGKGDSSIRYFEITDEPPFVHYLNTFSSKEPQRGMGFMPKRGLDVSKCEIARFYKLHERKCEPIVMTVPRKSDLFQDDLYPDTPGPEPALEADEWLSGQDAEPVLISLKEGYVPPKHREFRVTKRNILDVRPPASPRRSQSASEAPLSQQHTLETLLEEMKALRERVQAQEERITALENMLCELVDGTD", "length": 472 }, "evidence": [ { "id": "F6RCR6", "url": "https://omabrowser.org/oma/group/F6RCR6/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "Q920M5-1", "protein_name": "Coronin-6", "gene_name": "Coro6", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MSRRVVRQSKFRHVFGQAAKADQAYEDIRVSKVTWDSAFCAVNPKFLAIIVEAGGGGAFIVLPLAKTGRVDKNYPLVTGHTGPVLDIDWCPHNDNVIASASDDTTVMVWQIPDYTPVRNITEPVITLEGHSKRVGILSWHPTARNVLLSAGGDNVIIIWNVGTGEVLLSLDDIHPDVIHSVCWNSNGSLLATTCKDKTLRIIDPRKSQVVAERARPHEGARPLRAVFTADGKLLSTGFSRMSERQLALWDPNNFEEPVALQEMDTSNGVLLPFYDPDSSIVYLCGKGDSSIRYFEITEEPPFVHYLNTFSSKEPQRGMGFMPKRGLDVSKCEIARFYKLHERKCEPIIMTVPRKSDLFQDDLYPDTPGPEPALEADEWLSGQDAEPVLISLKEGYVPPKHRELRVTKRNILDVRPPASPRRSQSASEAPLSQHTLETLLEEIKALRDRVQAQEERITALENMLCELVDGTD", "length": 471 }, "evidence": [ { "id": "F6RCR6", "url": "https://omabrowser.org/oma/group/F6RCR6/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" } ], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 2, "go_terms": [ { "name": "actin filament", "id": "GO:0005884", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005884", "evidence": [ { "database": "UniProtKB", "id": "F6RCR6", "url": "https://www.uniprot.org/uniprotkb/F6RCR6" } ], "pmid": "" }, { "name": "plasma membrane", "id": "GO:0005886", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005886", "evidence": [ { "database": "UniProtKB", "id": "F6RCR6", "url": "https://www.uniprot.org/uniprotkb/F6RCR6" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 1, "go_terms": [ { "name": "actin filament organization", "id": "GO:0007015", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007015", "evidence": [ { "database": "UniProtKB", "id": "F6RCR6", "url": "https://www.uniprot.org/uniprotkb/F6RCR6" } ], "pmid": "" } ] }, { "name": "Molecular Function", "total": 1, "go_terms": [ { "name": "actin filament binding", "id": "GO:0051015", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0051015", "evidence": [ { "database": "UniProtKB", "id": "F6RCR6", "url": "https://www.uniprot.org/uniprotkb/F6RCR6" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 186, "end_pos": 188, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "F6RCR6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F6RCR6" }, { "id": "SM01166", "database": "SMART", "url": "http://smart.embl.de/smart/do_annotation.pl?DOMAIN=SM01166" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "DUF1899", "eco_id": "ECO_0000259", "start_pos": 4, "end_pos": 68, "start_aa": "Arg", "end_aa": "Gly", "glycosite_overlap": [] } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" }, { "name": "homologset.oma", "label": "OMA Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 186, "end_pos": 188 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ], "tool_support": { "graph_view": "yes" } }, { "uniprot_canonical_ac": "F6R2K6-1", "uniprot_ac": "F6R2K6", "uniprot_id": "F6R2K6_BOVIN", "mass": { "chemical_mass": 61394.0, "monoisotopic_mass": 61394.0 }, "refseq": {}, "gene_names": [ { "name": "UBAP1", "type": "recommended", "evidence": [ { "id": "F6R2K6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F6R2K6" } ] } ], "protein_names": [ { "name": "Ubiquitin-associated protein 1", "type": "recommended", "evidence": [ { "id": "F6R2K6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F6R2K6/entry#names_and_taxonomy" } ] } ], "function": [ { "annotation": "Component of the ESCRT-I complex, a regulator of vesicular trafficking process. Binds to ubiquitinated cargo proteins and is required for the sorting of endocytic ubiquitinated cargos into multivesicular bodies (MVBs). Plays a role in the proteasomal degradation of ubiquitinated cell-surface proteins, such as EGFR and BST2.", "evidence": [ { "database": "UniProtKB", "id": "A0A3Q1MPI2", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1MPI2#function" }, { "database": "UniProtKB", "id": "ARBA00056151", "url": "https://www.uniprot.org/uniprotkb/ARBA00056151#function" }, { "database": "UniProtKB", "id": "A0A3Q1N8U1", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1N8U1#function" }, { "database": "UniProtKB", "id": "F6R2K6", "url": "https://www.uniprot.org/uniprotkb/F6R2K6#function" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Bos taurus", "taxid": 9913, "evidence": [ { "database": "UniProtKB", "id": "F6R2K6", "url": "https://www.uniprot.org/uniprotkb/F6R2K6" } ], "common_name": "Bovine", "glygen_name": "Bovine", "reference_species": "Bos taurus [9913]" } ], "gene": [ { "name": "UBAP1", "url": "https://www.uniprot.org/uniprotkb/F6R2K6", "locus": { "chromosome": "8", "start_pos": 75650401, "end_pos": 75580437, "strand": "-", "evidence": [ { "database": "Ensembl Gene", "id": "ENSBTAG00000000320", "url": "https://www.ensembl.org/id/ENSBTAG00000000320" } ] } } ], "crossref": [ { "id": "F6R2K6", "url": "https://alphafold.ebi.ac.uk/entry/F6R2K6", "database": "AlphaFoldDB", "categories": [] }, { "id": "ENSBTAG00000000320", "url": "https://bgee.org/?page=gene&gene_id=ENSBTAG00000000320", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "cd14315", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd14315", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "cd14316", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd14316", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "517788", "url": "https://www.ncbi.nlm.nih.gov/gene/517788", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR009060", "url": "https://www.ebi.ac.uk/interpro/entry/IPR009060", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR015940", "url": "https://www.ebi.ac.uk/interpro/entry/IPR015940", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR023340", "url": "https://www.ebi.ac.uk/interpro/entry/IPR023340", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR038870", "url": "https://www.ebi.ac.uk/interpro/entry/IPR038870", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR042575", "url": "https://www.ebi.ac.uk/interpro/entry/IPR042575", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR049467", "url": "https://www.ebi.ac.uk/interpro/entry/IPR049467", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "A0A3Q1MPI2", "url": "https://www.orthodb.org/?gene=A0A3Q1MPI2", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A3Q1N8U1", "url": "https://www.orthodb.org/?gene=A0A3Q1N8U1", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "F6R2K6", "url": "https://www.orthodb.org/?gene=F6R2K6", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR15960", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR15960", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR15960:SF2", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR15960:SF2", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF21267", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF21267", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF22567", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF22567", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "R-BTA-917729", "url": "https://www.reactome.org/PathwayBrowser/#R-BTA-917729", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "A0A3Q1MPI2", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1MPI2", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A3Q1MPI2-1", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1MPI2-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A3Q1N8U1", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1N8U1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A3Q1N8U1-1", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1N8U1-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0AAA9U0S1", "url": "https://www.uniprot.org/uniprotkb/A0AAA9U0S1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0AAA9U0S1-1", "url": "https://www.uniprot.org/uniprotkb/A0AAA9U0S1-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "F6R2K6", "url": "https://www.uniprot.org/uniprotkb/F6R2K6", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "F6R2K6-1", "url": "https://www.uniprot.org/uniprotkb/F6R2K6-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "KGGAVRGRRREVGLQHGGCGTGGDYGDGLARGGQSWRWCSLFLGAVRSSAGTEPGRPVGGSTFRLLARQLRHSGTFSYLDDVPFKIGDKFKTPAKVGLPIGFSLPDCLQVVREVQYDFSLEKKTIEWAEDIKKIQEAQWEAERKAEEAEATVNSKSGPEGDSKMSFSKTHGAAAMPPPINPILASLQHNSILTPTRVSSSATKQKVLSPPHTKADFNPADFECEEDPFDNLELKTIDEKEELRNILVGTSGPIMAQLLDSNLPRGGSGSVLQEEEVLASLERATLDFKPLHKPNGFVTLPQLGNCEKMSLSSKVSLPPIPAVSNIKSLSFPKLDSDDSSQKTPKMASTFHSTSCLRSGTFWNFLKPSTQSSASELNGHPTLGLSALNLDSGTEVPTLTPPQTPSLSVLSVCTEESAPPNTRPTVTPPNFSVSQVPNTPSCPQAHSELQALSPSERHCVETVVNMGYSYECVLRAMKKKGENIEQILDYLFAHGQLCEKGFDPLLVEEALEMQQCSEEKMMEFLQLMSKFKEMGFELKDIKEALLLHNNDQDSALEDLMARAGAS", "length": 564, "header": "tr|F6R2K6-1|F6R2K6_BOVIN Isoform 1 of Ubiquitin-associated protein 1 OS=Bos taurus OX=9913 GN=UBAP1 PE=4 SV=3 CANONICAL=F6R2K6-1" }, "isoforms": [ { "isoform_ac": "A0A3Q1MPI2-1", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1MPI2/entry", "sequence": { "sequence": "MSGRPRDLGFSKGSKWLLRSWVQIFMYDFSLEKKTIEWAEDIKKIQEAQWEAERKAEEAEATVNSKSGPEGDSKMSFSKTHGAAAMPPPINPILASLQHNSILTPTRVSSSATKQKVLSPPHTKADFNPADFECEEDPFDNLELKTIDEKEELRNILVGTSGPIMAQLLDSNLPRGGSGSVLQEEEVLASLERATLDFKPLHKPNGFVTLPQLGNCEKMSLSSKVSLPPIPAVSNIKSLSFPKLDSDDSSQKTPKMASTFHSTSCLRSGTFWNFLKPSTQSSASELNGHPTLGLSALNLDSGTEVPTLTPPQTPSLSVLSVCTEESAPPNTRPTVTPPNFSVSQVPNTPSCPQAHSELQALSPSERHCVETVVNMGYSYECVLRAMKKKGENIEQILDYLFAHGQLCEKGFDPLLVEEALEMQQCSEEKMMEFLQLMSKFKEMGFELKDIKEALLLHNNDQDSALEDLMARAGAS", "length": 475, "header": "tr|A0A3Q1MPI2-1|F6R2K6_BOVIN Computationally mapped isoform of Ubiquitin-associated protein 1 OS=Bos taurus OX=9913 GN=UBAP1 PE=4 SV=2 CANONICAL=F6R2K6-1" }, "locus": { "chromosome": "8", "start_pos": 75649398, "end_pos": 75580974, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000068345.3", "url": "https://www.ensembl.org/id/ENSBTAT00000068345.3" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000073370.2", "url": "https://www.ensembl.org/id/ENSBTAP00000073370.2" } ] } }, { "isoform_ac": "A0A3Q1N8U1-1", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1N8U1/entry", "sequence": { "sequence": "MASKKLGADFHGTFSYLDDVPFKIGDKFKTPAKVGLPIGFSLPDCLQVVREVQYDFSLEKKTIEWAEDIKKIQEAQWEAERKAEEAEATVNSKSGPEGDSKMSFSKTHGAAAMPPPINPILASLQHNSILTPTRVSSSATKQKVLSPPHTKADFNPADFECEEDPFDNLELKTIDEKEELRNILVGTSGPIMAQLLDSNLPRGGSGSVLQEEEVLASLERATLDFKPLHKPNGFVTLPQLGNCEKMSLSSKVSLPPIPAVSNIKSLSFPKLDSDDSSQKTPKMASTFHSTSCLRSGTFWNFLKPSTQSSASELNGHPTLGLSALNLDSGTEVPTLTPPQTPSLSVLSVCTEESAPPNTRPTVTPPNFSVSQVPNTPSCPQAHSELQALSPSERHCVETVVNMGYSYECVLRAMKKKGENIEQILDYLFAHGQLCEKGFDPLLVEEALEMQQCSEEKMMEFLQLMSKFKEMGFELKDIKEALLLHNNDQDSALEDLMARAGAS", "length": 502, "header": "tr|A0A3Q1N8U1-1|F6R2K6_BOVIN Computationally mapped isoform of Ubiquitin-associated protein 1 OS=Bos taurus OX=9913 GN=UBAP1 PE=4 SV=1 CANONICAL=F6R2K6-1" }, "locus": { "chromosome": "8", "start_pos": 75649398, "end_pos": 75625616, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000076606.3", "url": "https://www.ensembl.org/id/ENSBTAT00000076606.3" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000067502.1", "url": "https://www.ensembl.org/id/ENSBTAP00000067502.1" } ] } }, { "isoform_ac": "A0AAA9U0S1-1", "url": "https://www.uniprot.org/uniprotkb/A0AAA9U0S1/entry", "sequence": { "sequence": "MASKKLGADFHGTFSYLDDVPFKIGDKFKTPAKVGLPIGFSLPDCLQVVREVQYDFSLEKKTIEWAEDIKKIQEAQWEAERKAEEAEATVNSKSGPEGDSKMSFSKTHGAAAMPPPINPILASLQHNSILTPTRVSSSATKQKVLSPPHTKADFNPADFECEEDPFDNLELKTIDEKEELRNILVGTSGPIMAQLLDSNLPRGGSGSVLQEEEVLASLERATLDFKPLHKPNGFVTLPQLGNCEKMSLSSKVSLPPIPAVSNIKSLSFPKLDSDDSSQKTPKMASTFHSTSCLRSGTFWNFLKPSTQSSASELNGHPTLGLSALNLDSGTEVPTLTPPQTPSLSVLSVCTEESAPPNTRPTILDYLFAHGQLCEKGFDPLLVEEALEMQQCSEEKMMEFLQLMSKFKEMGFELKDIKEALLLHNNDQDSALEDLMARAGAS", "length": 441, "header": "tr|A0AAA9U0S1-1|A0AAA9U0S1_BOVIN Computationally mapped isoform of Ubiquitin associated protein 1 OS=Bos taurus OX=9913 GN=UBAP1 PE=4 SV=1 CANONICAL=F6R2K6-1" }, "locus": { "chromosome": "8", "start_pos": 75649398, "end_pos": 75625616, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000101094.2", "url": "https://www.ensembl.org/id/ENSBTAT00000101094.2" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000102708.1", "url": "https://www.ensembl.org/id/ENSBTAP00000102708.1" } ] } }, { "isoform_ac": "F6R2K6-1", "url": "https://www.uniprot.org/uniprotkb/F6R2K6/entry", "sequence": { "sequence": "KGGAVRGRRREVGLQHGGCGTGGDYGDGLARGGQSWRWCSLFLGAVRSSAGTEPGRPVGGSTFRLLARQLRHSGTFSYLDDVPFKIGDKFKTPAKVGLPIGFSLPDCLQVVREVQYDFSLEKKTIEWAEDIKKIQEAQWEAERKAEEAEATVNSKSGPEGDSKMSFSKTHGAAAMPPPINPILASLQHNSILTPTRVSSSATKQKVLSPPHTKADFNPADFECEEDPFDNLELKTIDEKEELRNILVGTSGPIMAQLLDSNLPRGGSGSVLQEEEVLASLERATLDFKPLHKPNGFVTLPQLGNCEKMSLSSKVSLPPIPAVSNIKSLSFPKLDSDDSSQKTPKMASTFHSTSCLRSGTFWNFLKPSTQSSASELNGHPTLGLSALNLDSGTEVPTLTPPQTPSLSVLSVCTEESAPPNTRPTVTPPNFSVSQVPNTPSCPQAHSELQALSPSERHCVETVVNMGYSYECVLRAMKKKGENIEQILDYLFAHGQLCEKGFDPLLVEEALEMQQCSEEKMMEFLQLMSKFKEMGFELKDIKEALLLHNNDQDSALEDLMARAGAS", "length": 564, "header": "tr|F6R2K6-1|F6R2K6_BOVIN Isoform 1 of Ubiquitin-associated protein 1 OS=Bos taurus OX=9913 GN=UBAP1 PE=4 SV=3 CANONICAL=F6R2K6-1" }, "locus": { "chromosome": "8", "start_pos": 75649398, "end_pos": 75580415, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000036476.7", "url": "https://www.ensembl.org/id/ENSBTAT00000036476.7" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000036333.7", "url": "https://www.ensembl.org/id/ENSBTAP00000036333.7" } ] } } ], "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "other", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 425, "start_aa": "Thr", "end_pos": 425, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr425", "evidence": [ { "id": "", "database": "GlyGen", "url": "https://data.glygen.org/" } ], "filter_code": "000000000000000010000.00000000001000.0.01000" } ], "phosphorylation": [], "glycation": [], "keywords": [ "glycoprotein", "glycoprotein_predicted" ], "publication": [], "pathway": [ { "id": "R-BTA-917729", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-BTA-917729", "resource": "Reactome", "description": "Endosomal Sorting Complex Required For Transport (ESCRT)" } ], "orthologs": [], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 2, "go_terms": [ { "name": "cytosol", "id": "GO:0005829", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005829", "evidence": [ { "database": "UniProtKB", "id": "F6R2K6", "url": "https://www.uniprot.org/uniprotkb/F6R2K6" } ], "pmid": "" }, { "name": "ESCRT I complex", "id": "GO:0000813", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000813", "evidence": [ { "database": "UniProtKB", "id": "F6R2K6", "url": "https://www.uniprot.org/uniprotkb/F6R2K6" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 2, "go_terms": [ { "name": "protein transport", "id": "GO:0015031", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0015031", "evidence": [ { "database": "UniProtKB", "id": "F6R2K6", "url": "https://www.uniprot.org/uniprotkb/F6R2K6" } ], "pmid": "" }, { "name": "ubiquitin-dependent protein catabolic process via the multivesicular body sorting pathway", "id": "GO:0043162", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0043162", "evidence": [ { "database": "UniProtKB", "id": "F6R2K6", "url": "https://www.uniprot.org/uniprotkb/F6R2K6" } ], "pmid": "" } ] }, { "name": "Molecular Function", "total": 1, "go_terms": [ { "name": "ubiquitin binding", "id": "GO:0043130", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0043130", "evidence": [ { "database": "UniProtKB", "id": "F6R2K6", "url": "https://www.uniprot.org/uniprotkb/F6R2K6" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 428, "end_pos": 430, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "F6R2K6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F6R2K6" }, { "id": "PS50030", "database": "PROSITE", "url": "https://prosite.expasy.org/PS50030" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "UBA", "eco_id": "ECO_0000259", "start_pos": 451, "end_pos": 492, "start_aa": "Ser", "end_aa": "His", "glycosite_overlap": [] }, { "evidence": [ { "id": "F6R2K6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F6R2K6" }, { "id": "PS51497", "database": "PROSITE", "url": "https://prosite.expasy.org/PS51497" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "UMA", "eco_id": "ECO_0000259", "start_pos": 79, "end_pos": 125, "start_aa": "Leu", "end_aa": "Ile", "glycosite_overlap": [] } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [ 425 ], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 428, "end_pos": 430 } ] }, "class_list": [], "section_stats": [ { 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"sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ], "tool_support": { "graph_view": "yes" } }, { "uniprot_canonical_ac": "F1N5A5-1", "uniprot_ac": "F1N5A5", "uniprot_id": "F1N5A5_BOVIN", "mass": { "chemical_mass": 21260.0, "monoisotopic_mass": 21260.0 }, "refseq": {}, "gene_names": [], "protein_names": [ { "name": "KRAB domain-containing protein", "type": "recommended", "evidence": [ { "id": "F1N5A5", "database": "UniProtKB", "url": 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"url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd07765", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "IPR001909", "url": "https://www.ebi.ac.uk/interpro/entry/IPR001909", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR036051", "url": "https://www.ebi.ac.uk/interpro/entry/IPR036051", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR050169", "url": "https://www.ebi.ac.uk/interpro/entry/IPR050169", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "PTHR23232", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR23232", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR23232:SF157", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR23232:SF157", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF01352", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF01352", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "A0A3Q1MPK1", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1MPK1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A3Q1MPK1-1", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1MPK1-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0ABI0NJS6", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NJS6", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0ABI0NJS6-1", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NJS6-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "F1N5A5", "url": "https://www.uniprot.org/uniprotkb/F1N5A5", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "F1N5A5-1", "url": "https://www.uniprot.org/uniprotkb/F1N5A5-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MTHSEGRLTFQDVAIDFTQEEWECLDPGQRKLYRDVMVENYRNLASLGLVSKVDLVTFLELLKDPRNMRRMETTAIYPAMSPQDTQDLRTKNPALEDVFPKANLGIYQTFHLRNLNLMTDWEFTRVYERQRGCLYGHKEMETVTHNATLLQKEMSNVSQIGKNSNFNLQYLPRSKMKDTIM", "length": 181, "header": "tr|F1N5A5-1|F1N5A5_BOVIN Isoform 1 of KRAB domain-containing protein OS=Bos taurus OX=9913 GN= PE=4 SV=5 CANONICAL=F1N5A5-1" }, "isoforms": [ { "isoform_ac": "A0A3Q1MPK1-1", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1MPK1/entry", "sequence": { "sequence": "MTHSEGRLTFQDVAIDFTQEEWECLDPGQRKLYRDVMVENYRNLASLGLVSKVDLVTFLELLKDPRNMRRMETTAIYPGLVVSKVDLVTFLEQMKDPRNISRMETMAMYPEWNRNVKCTMNI", "length": 122, "header": "tr|A0A3Q1MPK1-1|F1N5A5_BOVIN Computationally mapped isoform of KRAB domain-containing protein OS=Bos taurus OX=9913 GN= PE=4 SV=3 CANONICAL=F1N5A5-1" }, "locus": { "chromosome": "18", "start_pos": 60302838, "end_pos": 60271502, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000083880.3", "url": 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"https://www.ensembl.org/id/ENSBTAP00000104478.1" } ] } }, { "isoform_ac": "F1N5A5-1", "url": "https://www.uniprot.org/uniprotkb/F1N5A5/entry", "sequence": { "sequence": "MTHSEGRLTFQDVAIDFTQEEWECLDPGQRKLYRDVMVENYRNLASLGLVSKVDLVTFLELLKDPRNMRRMETTAIYPAMSPQDTQDLRTKNPALEDVFPKANLGIYQTFHLRNLNLMTDWEFTRVYERQRGCLYGHKEMETVTHNATLLQKEMSNVSQIGKNSNFNLQYLPRSKMKDTIM", "length": 181, "header": "tr|F1N5A5-1|F1N5A5_BOVIN Isoform 1 of KRAB domain-containing protein OS=Bos taurus OX=9913 GN= PE=4 SV=5 CANONICAL=F1N5A5-1" }, "locus": { "chromosome": "18", "start_pos": 60302838, "end_pos": 60290701, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000042978.6", "url": "https://www.ensembl.org/id/ENSBTAT00000042978.6" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000040579.6", "url": "https://www.ensembl.org/id/ENSBTAP00000040579.6" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [], "orthologs": [], "go_annotation": { "categories": [ { "name": "Biological Process", "total": 2, "go_terms": [ { "name": "negative regulation of transcription by RNA polymerase II", "id": "GO:0000122", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000122", "evidence": [ { "database": "UniProtKB", "id": "F1N5A5", "url": "https://www.uniprot.org/uniprotkb/F1N5A5" } ], "pmid": "" }, { "name": "regulation of DNA-templated transcription", "id": "GO:0006355", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006355", "evidence": [ { "database": "UniProtKB", "id": "F1N5A5", "url": "https://www.uniprot.org/uniprotkb/F1N5A5" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 1, "go_terms": [ { "name": "nucleus", "id": "GO:0005634", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005634", "evidence": [ { "database": "UniProtKB", "id": "F1N5A5", "url": "https://www.uniprot.org/uniprotkb/F1N5A5" } ], "pmid": "" } ] }, { "name": "Molecular Function", "total": 2, "go_terms": [ { "name": "DNA-binding 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"InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR035969", "url": "https://www.ebi.ac.uk/interpro/entry/IPR035969", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR036009", "url": "https://www.ebi.ac.uk/interpro/entry/IPR036009", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR036016", "url": "https://www.ebi.ac.uk/interpro/entry/IPR036016", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "A0A3Q1MTE5", "url": "https://www.orthodb.org/?gene=A0A3Q1MTE5", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A3Q1MVQ7", "url": "https://www.orthodb.org/?gene=A0A3Q1MVQ7", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "F1N7K9", "url": "https://www.orthodb.org/?gene=F1N7K9", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR47666", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR47666", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR47666:SF2", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR47666:SF2", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00566", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00566", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF02893", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF02893", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "XP_010808040", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_010808040", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A3Q1MTE5", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1MTE5", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A3Q1MTE5-1", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1MTE5-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A3Q1MVQ7", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1MVQ7", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A3Q1MVQ7-1", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1MVQ7-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "F1N7K9", "url": "https://www.uniprot.org/uniprotkb/F1N7K9", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "F1N7K9-1", "url": "https://www.uniprot.org/uniprotkb/F1N7K9-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MWLKPEEVLLKNALKLWVTQKSNCYFILQRRRGHGEGGGRLTGRLVGALDAVLDSNARVAPFRILLQVPGSQAYSPIACGELLSGSDVYWAVATGATLEEINQHWDWLEQNLLHTLSVFDNKDDIASFVKGKVKALIAEETSSRLAEQEEEPEKFREALVKFETRFNFPEAEKLITYYSCCCWKGRVPRQGWLYLSINHLCFYSFFLGKELKLVIPWVDVQRLERTSNVFLTDTIRITTQNKERDFSMFLNLDEVFKIMEQLADVTLRRLLDNEGFDLDPGLQEPSQITKRDLEARAQNEFFRAFFRLPRREKLHAVLDCSLWTPFSRCHTAGQMFTSDSYICFASKEAGCCKVILPLREVVSIEKMEDTSLLPNPIIVSIRSKMAFQFIELRDRDSLVEGLLARLKLVHADHPVHYDTTLDEELTSPVFHSTSLCSGSHRFGGLEMVSSQNSEEREKETSPRMHPEAFRQSGSQSPDSGLSREQIKVSLWKDHFVEYGRTVCMFRTEKIRKLVAMGIPESLRGRLWLLFSDAVTDLAAHPGYYGNLVEESMGKCCLVTEEIERDLHRSLPEHPAFQNETGIAALRRVLTAYAHRNPKIGYCQSMNILTSVLLLYAKEEEAFWLLVAVCERMLPDYFNHRVIGAQVDQSVFEELIKEQLPELAEHMHDLSALASISLSWFLTLFLSIMPLESAVNVVDCFFYDGIKAIFQLGLAVLEATAEGLCSSKDDSQAFMVLSRFLDHVKNEDSPGPPIGSHHAFFSDDQEPCPVTDIADLIRDSYEKFGDQSVAQIEHMRCRHRIRVLQGHEDTTKQNVLRVVIPEVSVLPEDLEELYDLFKREHMMSCYWEQPRPMAPRHDPSRPYAEQYRIDAQQFARLFQLVSPWTCGAHTEILAERTFRLLDENMDHLIEFKAFVSCLDIMYNGEMNEKIKLLYRLHIPPALTENDRDSQSPLKNPLLSTSRPLVFGKSNGDTIDYQKQLKQMIKDLAKEKDKTEKELPKMSQREFIQFCKTLYSMFHEDPEENDLYQAIATVTTLLLQIGEVGQRGSSSGSGSQEGGEELQASAPSPSSEQDLVFAETDTGQSPQASQAFPEEAQGDWTVSLEHILASLLTEQSLVNFFEKPLDIKSKLENAKLNQYSLKTCEMSRQSQPELKLSSP", "length": 1157, "header": "tr|F1N7K9-1|F1N7K9_BOVIN Isoform 1 of TBC1 domain family member 8 OS=Bos taurus OX=9913 GN=TBC1D8 PE=4 SV=4 CANONICAL=F1N7K9-1" }, "isoforms": [ { "isoform_ac": "A0A3Q1MTE5-1", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1MTE5/entry", "sequence": { "sequence": "MWLKPEEVLLKNALKLWVTQKSNCYFILQRRRGHGEGGGRLTGATLEEINQHWDWLEQNLLHTLSVFDNKDDIASFVKGKVKALIAEETSSRLAEQEEEPEKFREALVKFETRFNFPEAEKLITYYSCCCWKGRVPRQGWLYLSINHLCFYSFFLGKELKLVIPWVDVQRLERTSNVFLTDTIRITTQNKERDFSMFLNLDEVFKIMEQLADVTLRRLLDNEGFDLDPGLQEPSQITKRDLEARAQNEFFRAFFRLPRREKLHAVLDCSLWTPFSRCHTAGQMFTSDSYICFASKEAGCCKVILPLREVVSIEKMEDTSLLPNPIIVSIRSKMAFQFIELRDRDSLVEGLLARLKLVHADHPVHYDTTLDEELTSPVFHSTSLCSGSHRFGGLEMVSSQNSEEREKETSPRMHPEAFRQSGSQSPDSGLSREQIKVSLWKDHFVEYGRTVCMFRTEKIRKLVAMGIPESLRGRLWLLFSDAVTDLAAHPGYYGNLVEESMGKCCLVTEEIERDLHRSLPEHPAFQNETGIAALRRVLTAYAHRNPKIGYCQSMNILTSVLLLYAKEEEAFWLLVAVCERMLPDYFNHRVIGAQVDQSVFEELIKEQLPELAEHMHDLSALASISLSWFLTLFLSIMPLESAVNVVDCFFYDGIKAIFQLGLAVLEATAEGLCSSKDDSQAFMVLSRFLDHVKNEDSPGPPIGSHHAFFSDDQEPCPVTDIADLIRDSYEKFGDQSVAQIEHMRCRHRIRVLQGHEDTTKQNVLRVVIPEVSVLPEDLEELYDLFKREHMMSCYWEQPRPMAPRHDPSRPYAEQYRIDAQQFARLFQLVSPWTCGAHTEILAERTFRLLDENMDHLIEFKAFVSCLDIMYNGEMNEKIKLLYRLHIPPALTENDRDSQSPLKNPLLSTSRPLVFGKSNGDTIDYQKQLKQMIKDLAKEKDKTEKELPKMSQREFIQFCKTLYSMFHEDPEENDLYQAIATVTTLLLQIGEVGQRGSSSGSGSQEGGEELQASAPSPSSEQDLVFAETDTGQSPQASQAFPEEAQGDWTVSLEHILASLLTEQSLVNFFEKPLDIKSKLENAKLNQYSLKTCEMSRQSQPELKLSSP", "length": 1105, "header": "tr|A0A3Q1MTE5-1|F1N7K9_BOVIN Computationally mapped isoform of TBC1 domain family member 8 OS=Bos taurus OX=9913 GN=TBC1D8 PE=4 SV=1 CANONICAL=F1N7K9-1" }, "locus": { "chromosome": "11", "start_pos": 6119204, "end_pos": 5978677, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000074892.2", "url": "https://www.ensembl.org/id/ENSBTAT00000074892.2" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000073564.1", "url": "https://www.ensembl.org/id/ENSBTAP00000073564.1" } ] } }, { "isoform_ac": "A0A3Q1MVQ7-1", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1MVQ7/entry", "sequence": { "sequence": "MGVIFSFFIEGRLVGALDAVLDSNARVAPFRILLQVPGSQAYSPIACGATLEEINQHWDWLEQNLLHTLSVFDNKDDIASFVKGKVKALIAEETSSRLAEQEEEPEKFREALVKFETRFNFPEAEKLITYYSCCCWKGRVPRQGWLYLSINHLCFYSFFLGKELKLVIPWVDVQRLERTSNVFLTDTIRITTQNKERDFSMFLNLDEVFKIMEQLADVTLRRLLDNEGFDLDPGLQEPSQITKRDLEARAQNEFFRAFFRLPRREKLHAVLDCSLWTPFSRCHTAGQMFTSDSYICFASKEAGCCKVILPLREVVSIEKMEDTSLLPNPIIVSIRSKMAFQFIELRDRDSLVEGLLARLKLVHADHPVHYDTTLDEELTSPVFHSTSLCSGSHRFGGLEMVSSQNSEEREKETSPRMHPEAFRQSGSQSPDSGLSREQIKVSLWKDHFVEYGRTVCMFRTEKIRKLVAMGIPESLRGRLWLLFSDAVTDLAAHPGYYGNLVEESMGKCCLVTEEIERDLHRSLPEHPAFQNETGIAALRRVLTAYAHRNPKIGYCQSMNILTSVLLLYAKEEEAFWLLVAVCERMLPDYFNHRVIGAQVDQSVFEELIKEQLPELAEHMHDLSALASISLSWFLTLFLSIMPLESAVNVVDCFFYDGIKAIFQLGLAVLEATAEGLCSSKDDSQAFMVLSRFLDHVKNEDSPGPPIGSHHAFFSDDQEPCPVTDIADLIRDSYEKFGDQSVAQIEHMRCRHRIRVLQGHEDTTKQNVLRVVIPEVSVLPEDLEELYDLFKREHMMSCYWEQPRPMAPRHDPSRPYAEQYRIDAQQFARLFQLVSPWTCGAHTEILAERTFRLLDENMDHLIEFKAFVSCLDIMYNGEMNEKIKLLYRLHIPPALTENDRDSQSPLKNPLLSTSRPLVFGKSNGDTIDYQKQLKQMIKDLAKEKDKTEKELPKMSQREFIQFCKTLYSMFHEDPEENDLYQAIATVTTLLLQIGEVGQRGSSSGSGSQEGGEELQASAPSPSSEQDLVFAETDTGQSPQASQAFPEEAQGDWTVSLEHILASLLTEQSLVNFFEKPLDIKSKLENAKLNQYSLKTCEMSRQSQPELKLSSP", "length": 1110, "header": "tr|A0A3Q1MVQ7-1|F1N7K9_BOVIN Computationally mapped isoform of TBC1 domain family member 8 OS=Bos taurus OX=9913 GN=TBC1D8 PE=4 SV=2 CANONICAL=F1N7K9-1" }, "locus": { "chromosome": "11", "start_pos": 6075794, "end_pos": 5978677, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000067120.2", "url": "https://www.ensembl.org/id/ENSBTAT00000067120.2" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000059211.2", "url": "https://www.ensembl.org/id/ENSBTAP00000059211.2" } ] } }, { "isoform_ac": "F1N7K9-1", "url": "https://www.uniprot.org/uniprotkb/F1N7K9/entry", "sequence": { "sequence": "MWLKPEEVLLKNALKLWVTQKSNCYFILQRRRGHGEGGGRLTGRLVGALDAVLDSNARVAPFRILLQVPGSQAYSPIACGELLSGSDVYWAVATGATLEEINQHWDWLEQNLLHTLSVFDNKDDIASFVKGKVKALIAEETSSRLAEQEEEPEKFREALVKFETRFNFPEAEKLITYYSCCCWKGRVPRQGWLYLSINHLCFYSFFLGKELKLVIPWVDVQRLERTSNVFLTDTIRITTQNKERDFSMFLNLDEVFKIMEQLADVTLRRLLDNEGFDLDPGLQEPSQITKRDLEARAQNEFFRAFFRLPRREKLHAVLDCSLWTPFSRCHTAGQMFTSDSYICFASKEAGCCKVILPLREVVSIEKMEDTSLLPNPIIVSIRSKMAFQFIELRDRDSLVEGLLARLKLVHADHPVHYDTTLDEELTSPVFHSTSLCSGSHRFGGLEMVSSQNSEEREKETSPRMHPEAFRQSGSQSPDSGLSREQIKVSLWKDHFVEYGRTVCMFRTEKIRKLVAMGIPESLRGRLWLLFSDAVTDLAAHPGYYGNLVEESMGKCCLVTEEIERDLHRSLPEHPAFQNETGIAALRRVLTAYAHRNPKIGYCQSMNILTSVLLLYAKEEEAFWLLVAVCERMLPDYFNHRVIGAQVDQSVFEELIKEQLPELAEHMHDLSALASISLSWFLTLFLSIMPLESAVNVVDCFFYDGIKAIFQLGLAVLEATAEGLCSSKDDSQAFMVLSRFLDHVKNEDSPGPPIGSHHAFFSDDQEPCPVTDIADLIRDSYEKFGDQSVAQIEHMRCRHRIRVLQGHEDTTKQNVLRVVIPEVSVLPEDLEELYDLFKREHMMSCYWEQPRPMAPRHDPSRPYAEQYRIDAQQFARLFQLVSPWTCGAHTEILAERTFRLLDENMDHLIEFKAFVSCLDIMYNGEMNEKIKLLYRLHIPPALTENDRDSQSPLKNPLLSTSRPLVFGKSNGDTIDYQKQLKQMIKDLAKEKDKTEKELPKMSQREFIQFCKTLYSMFHEDPEENDLYQAIATVTTLLLQIGEVGQRGSSSGSGSQEGGEELQASAPSPSSEQDLVFAETDTGQSPQASQAFPEEAQGDWTVSLEHILASLLTEQSLVNFFEKPLDIKSKLENAKLNQYSLKTCEMSRQSQPELKLSSP", "length": 1157, "header": "tr|F1N7K9-1|F1N7K9_BOVIN Isoform 1 of TBC1 domain family member 8 OS=Bos taurus OX=9913 GN=TBC1D8 PE=4 SV=4 CANONICAL=F1N7K9-1" }, "locus": { "chromosome": "11", "start_pos": 6119204, "end_pos": 5978677, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000036694.6", "url": "https://www.ensembl.org/id/ENSBTAT00000036694.6" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000036550.6", "url": "https://www.ensembl.org/id/ENSBTAP00000036550.6" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [], "orthologs": [], "go_annotation": { "categories": [ { "name": "Molecular Function", "total": 2, "go_terms": [ { "name": "GTPase activator activity", "id": "GO:0005096", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005096", "evidence": [ { "database": "UniProtKB", "id": "F1N7K9", "url": "https://www.uniprot.org/uniprotkb/F1N7K9" } ], "pmid": "" }, { "name": "calcium ion binding", "id": "GO:0005509", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005509", "evidence": [ { "database": "UniProtKB", "id": "F1N7K9", "url": "https://www.uniprot.org/uniprotkb/F1N7K9" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 1, "go_terms": [ { "name": "system process", "id": "GO:0003008", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003008", "evidence": [ { "database": "UniProtKB", "id": "F1N7K9", "url": "https://www.uniprot.org/uniprotkb/F1N7K9" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 578, "end_pos": 580, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [ { "pdb_id": "AF-F1N7K9-F1", "pdb_chain": "global", "start_pos": 1, "end_pos": 1157, "overlap": "1.0", "method": "AlphaFold", "type": "alphafold", "resolution": -1.0, "url": "https://data.glygen.org/ln2downloads/pdb/current/AF-F1N7K9-F1.pdb", "url_external": "https://alphafold.ebi.ac.uk/entry/F1N7K9" } ], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "F1N7K9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1N7K9" }, { "id": "PS50222", "database": "PROSITE", "url": "https://prosite.expasy.org/PS50222" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "EF-hand", "eco_id": "ECO_0000259", "start_pos": 888, "end_pos": 923, "start_aa": "His", "end_aa": "Gly", "glycosite_overlap": [] }, { "evidence": [ { "id": "F1N7K9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1N7K9" }, { "id": "PS50086", "database": "PROSITE", "url": "https://prosite.expasy.org/PS50086" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "Rab-GAP TBC", "eco_id": "ECO_0000259", "start_pos": 517, "end_pos": 704, "start_aa": "Gly", "end_aa": "Gly", "glycosite_overlap": [] } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 578, "end_pos": 580 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ], "tool_support": { "graph_view": "yes" } }, { "uniprot_canonical_ac": "F1N5W2-1", "uniprot_ac": "F1N5W2", "uniprot_id": "F1N5W2_BOVIN", "mass": { "chemical_mass": 160908.0, "monoisotopic_mass": 160908.0 }, "refseq": {}, "gene_names": [ { "name": "ZNF226", "type": "recommended", "evidence": [ { "id": "F1N5W2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1N5W2" } ] } ], "protein_names": [ { "name": "Zinc finger protein 226", "type": "synonym", "evidence": [ { "id": "F1N5W2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1N5W2/entry#names_and_taxonomy" } ] } ], "function": [ { "annotation": "May be involved in transcriptional regulation.", "evidence": [ { "database": "UniProtKB", "id": "A0A3Q1MUX5", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1MUX5#function" }, { "database": "UniProtKB", "id": "ARBA00003767", "url": "https://www.uniprot.org/uniprotkb/ARBA00003767#function" }, { "database": "UniProtKB", "id": "A0AAA9S9S3", "url": "https://www.uniprot.org/uniprotkb/A0AAA9S9S3#function" }, { "database": "UniProtKB", "id": "A0AAA9TBU5", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TBU5#function" }, { "database": "UniProtKB", "id": "A0AAA9T3L9", "url": "https://www.uniprot.org/uniprotkb/A0AAA9T3L9#function" }, { "database": "UniProtKB", "id": "F1N5W2", "url": "https://www.uniprot.org/uniprotkb/F1N5W2#function" }, { "database": "UniProtKB", "id": "F6QSN7", "url": "https://www.uniprot.org/uniprotkb/F6QSN7#function" }, { "database": "UniProtKB", "id": "A0AAA9TLB6", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TLB6#function" }, { "database": "UniProtKB", "id": "A0AAA9TSC7", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TSC7#function" }, { "database": "UniProtKB", "id": "A0ABI0NN04", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NN04#function" }, { "database": "UniProtKB", "id": "A0ABI0P719", "url": "https://www.uniprot.org/uniprotkb/A0ABI0P719#function" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Bos taurus", "taxid": 9913, "evidence": [ { "database": "UniProtKB", "id": "F1N5W2", "url": "https://www.uniprot.org/uniprotkb/F1N5W2" } ], "common_name": "Bovine", "glygen_name": "Bovine", "reference_species": "Bos taurus [9913]" } ], "gene": [ { "name": "ZNF226", "url": "https://www.uniprot.org/uniprotkb/F1N5W2", "locus": {} } ], "crossref": [ { "id": "F1N5W2", "url": "https://alphafold.ebi.ac.uk/entry/F1N5W2", "database": "AlphaFoldDB", "categories": [] }, { "id": "ENSBTAG00000049610", "url": "https://bgee.org/?page=gene&gene_id=ENSBTAG00000049610", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "ENSBTAG00000050035", "url": "https://bgee.org/?page=gene&gene_id=ENSBTAG00000050035", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "cd07765", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd07765", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "789006", "url": "https://www.ncbi.nlm.nih.gov/gene/789006", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR001909", "url": "https://www.ebi.ac.uk/interpro/entry/IPR001909", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR013087", "url": "https://www.ebi.ac.uk/interpro/entry/IPR013087", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR036051", "url": "https://www.ebi.ac.uk/interpro/entry/IPR036051", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR036236", "url": "https://www.ebi.ac.uk/interpro/entry/IPR036236", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR050636", "url": "https://www.ebi.ac.uk/interpro/entry/IPR050636", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "bta:789006", "url": "https://www.genome.jp/dbget-bin/www_bget?bta:789006", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "WISHHLD", "url": "https://omabrowser.org/oma/group/WISHHLD/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "A0A3Q1MUX5", "url": "https://www.orthodb.org/?gene=A0A3Q1MUX5", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "F6QSN7", "url": "https://www.orthodb.org/?gene=F6QSN7", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR23235", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR23235", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR23235:SF142", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR23235:SF142", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR24381", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR24381", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR24381:SF452", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR24381:SF452", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR47772", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR47772", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR47772:SF15", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR47772:SF15", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR47772:SF8", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR47772:SF8", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00096", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00096", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF01352", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF01352", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "R-BTA-212436", "url": "https://www.reactome.org/PathwayBrowser/#R-BTA-212436", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "A0A3Q1MUX5", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1MUX5", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A3Q1MUX5-1", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1MUX5-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0AAA9S9S3", "url": "https://www.uniprot.org/uniprotkb/A0AAA9S9S3", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0AAA9S9S3-1", "url": "https://www.uniprot.org/uniprotkb/A0AAA9S9S3-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0AAA9T3L9", "url": "https://www.uniprot.org/uniprotkb/A0AAA9T3L9", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0AAA9T3L9-1", "url": "https://www.uniprot.org/uniprotkb/A0AAA9T3L9-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0AAA9TBU5", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TBU5", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0AAA9TBU5-1", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TBU5-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0AAA9TLB6", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TLB6", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0AAA9TLB6-1", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TLB6-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0AAA9TSC7", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TSC7", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0AAA9TSC7-1", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TSC7-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0ABI0NN04", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NN04", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0ABI0NN04-1", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NN04-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0ABI0P719", "url": "https://www.uniprot.org/uniprotkb/A0ABI0P719", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0ABI0P719-1", "url": "https://www.uniprot.org/uniprotkb/A0ABI0P719-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "F1N5W2", "url": "https://www.uniprot.org/uniprotkb/F1N5W2", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "F1N5W2-1", "url": "https://www.uniprot.org/uniprotkb/F1N5W2-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "F6QSN7", "url": "https://www.uniprot.org/uniprotkb/F6QSN7", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "F6QSN7-1", "url": "https://www.uniprot.org/uniprotkb/F6QSN7-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MTTFKEAVTFTDVAVTFTEEEFRLLDSAQKKLYQDVMLENFRNLVSVGCHPFRHDIFHLEKEKRLWVVKTATQREGKSEEKIQSEMETISEVGPHEELSCWQIWRHIASDLTRCQDSRIKCSEFHQQCDSPGQNGAGLSVIHTGQIPSQCNECTKSFDDLSNFDLHQQIHSGEKSHTCCECGKSFCYSSALRIHQRVHSGEKRYKCDECGKEFSQSSQLQIHQKVHTVEKPFRCEQCGKGFSRRSTLTVHCKLHTGDKPYTCDKCGRAFIHASHLQEHQRIHTGEKPFKCDICGKNFRRRSALNSHCMVHTGEKPYKCEECGKCFTCSSNLHIHQRVHTGEKPYKCEECSKCFVQPSQFQAHRRIHTGEKPYVCKVCGKGFIYSSSFQAHQGVHTGEKPYRCDECGKNFRMKIHYQVHLVVHTGEKPYKCEVCGKGFRQSSYLKIHQKAHSIEKPYKCEECGQGFNQNSRLQIHQLIHTGEKPYKCEECGKGFSRRADLKIHCRIHTGEKPYNCEECGKVFSQASHLLTHQRVHSGEKPFKCEECDKSFGRSSHLQAHQKVHTGEKPFKCEECGKGFKWSLNLDMHQRVHTGEKPYKCGECGKHFSQASSLQLHQSVHTGEKPYRTLHFPGRREKMNMFMEAVTFKDVAVAFTEEELGLLDSAQRKLYQDVMVENFRNLVSVEENNQSELSAIQERGLHEELSCWQIWQQIANDLTRCQDSMINNCQLHKQGYSLHQVGSGLSIQISEDENYILNEKAGGPGDTGNPRFASLRARDSWRKSSLTESQNYQNRYQEISTQSKLCRCKADVDSIGRISYHLDDRGVHKNEKSYCHNDYRKDSTVSTLDQNSMIHTGQKPYQCNECKRTFTSLSTFDLHQQLHSKETSHVCDECGKGFRYSSVLHIHQRVHIGEECSVFAECGKEFHQSSQLQTHQKVHSIKKPFTCEECGKGFSRRSALSIHCKVHTGEKPYTCEECGRAFSQASHLQDHQRVHTGEKPFICDACGKSFSRNSHLQSHQRVHTGEKPYKCEECGKGFICSSNLYIHQRVHTGEKPYKCEECGKGFSRPSSLQAHQGIHTGEKSYVCNVCGKGFTLSSNLQAHQRVHTGEKPYKCEECGKNFRRNSHYQVHLVVHTGEKPYKCEVCGKGFSQSSYLQIHQKAHSVEKPYKCKECGQGFNQNSRLQIHQLIHTGEKPYKCEECGKGFSRRADLKIHCRIHTGEKPYNCEECGKVFRQASNLLAHQRVHSGEKPFKCEECGKSFGRSSHLQAHQKVHTGEKPYKCEECGKGFKWSLNLDMHQRVHTGEKPYKCGECGKHFSQASSLQLHQSVHTGEKPYRCDVCGKVFSRSSQLQSHQRVHTGEKPYKCEMCGKSFSWRSNLTIHQRIHAADKSYKSHRGGKTIRDST", "length": 1403, "header": "tr|F1N5W2-1|F1N5W2_BOVIN Isoform 1 of Zinc finger protein 226 OS=Bos taurus OX=9913 GN=ZNF226 PE=3 SV=4 CANONICAL=F1N5W2-1" }, "isoforms": [ { "isoform_ac": "A0A3Q1MUX5-1", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1MUX5/entry", "sequence": { "sequence": "MIRFRTLHFPGRREKMNMFMEAVTFKDVAVAFTEEELGLLDSAQRKLYQDVMVENFRNLVSVEENNQSELSAIQERGLHEELSCWQIWQQIANDLTRCQDSMINNCQLHKQGYSLHQVGSGLSIQISEDENYILNEKAGGPGDTGNPRFASLRARDSWRKSSLTESQNYQNRYQEISTQSKLCRCKADVDSIGRISYHLDDRGVHKNEKSYCHNDYRKDSTVSTLDQNSMIHTGQKPYQCNECKRTFTSLSTFDLHQQLHSKETSHVCDECGKGFRYSSVLHIHQRVHIGEECSVFAECGKEFHQSSQLQTHQKVHSIKKPFTCEECGKGFSRRSALSIHCKVHTGEKPYTCEECGRAFSQASHLQDHQRVHTGEKPFICDACGKSFSRNSHLQSHQRVHTGEKPYKCEECGKGFICSSNLYIHQRVHTGEKPYKCEECGKGFSRPSSLQAHQGIHTGEKSYVCNVCGKGFTLSSNLQAHQRVHTGEKPYKCEECGKNFRRNSHYQVHLVVHTGEKPYKCEVCGKGFSQSSYLQIHQKAHSVEKPYKCKECGQGFNQNSRLQIHQLIHTGEKPYKCEECGKGFSRRADLKIHCRIHTGEKPYNCEECGKVFRQASNLLAHQRVHSGEKPFKCEECGKSFGRSSHLQAHQKVHTGEKPYKCEECGKGFKWSLNLDMHQRVHTGEKPYKCGECGKHFSQASSLQLHQSVHTGEKPYRCDVCGKVFSRSSQLQSHQRVHTGEKPYKCEMCGKSFSWRSNLTIHQRIHAADKSYKSHRGGKTIRDST", "length": 783, "header": "tr|A0A3Q1MUX5-1|F1N5W2_BOVIN Computationally mapped isoform of Zinc finger protein 226 OS=Bos taurus OX=9913 GN=ZNF226 PE=3 SV=3 CANONICAL=F1N5W2-1" }, "locus": { "chromosome": "18", "start_pos": 52148271, "end_pos": 52137656, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000081112.3", "url": "https://www.ensembl.org/id/ENSBTAT00000081112.3" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000074525.3", "url": "https://www.ensembl.org/id/ENSBTAP00000074525.3" } ] } }, { "isoform_ac": "A0AAA9S9S3-1", "url": "https://www.uniprot.org/uniprotkb/A0AAA9S9S3/entry", "sequence": { "sequence": "MLLICDCQAAAPRNIPVIKELRLFELTEARTPMPHWCPGKEAVRTLHFPGRREKMNMFMEAVTFKDVAVAFTEEELGLLDSAQRKLYQDVMVENFRNLVSVEENNQSELSAIQERGLHEELSCWQIWQQIANDLTRCQDSMINNCQLHKQGYSLHQVGSGLSIQISEDENYILNEKAGGPGDTGNPRFASLRARDSWRKSSLTESQNYQNRYQEISTQSKLCRCKADVDSIGRISYHLDDRGVHKNEKSYCHNDYRKDSTVSTLDQNSMIHTGQKPYQCNECKRTFTSLSTFDLHQQLHSKETSHVCDECGKGFRYSSVLHIHQRVHIGEECSVFAECGKEFHQSSQLQTHQKVHSIKKPFTCEECGKGFSRRSALSIHCKVHTGEKPYTCEECGRAFSQASHLQDHQRVHTGEKPFICDACGKSFSRNSHLQSHQRVHTGEKPYKCEECGKGFICSSNLYIHQRVHTGEKPYKCEECGKGFSRPSSLQAHQGIHTGEKSYVCNVCGKGFTLSSNLQAHQRVHTGEKPYKCEECGKNFRRNSHYQVHLVVHTGEKPYKCEVCGKGFSQSSYLQIHQKAHSVEKPYKCKECGQGFNQNSRLQIHQLIHTGEKPYKCEECGKGFSRRADLKIHCRIHTGEKPYNCEECGKVFRQASNLLAHQRVHSGEKPFKCEECGKSFGRSSHLQAHQKVHTGEKPYKCEECGKGFKWSLNLDMHQRVHTGEKPYKCGECGKHFSQASSLQLHQSVHTGEKPYRCDVCGKVFSRSSQLQSHQRVHTGEKPYKCEMCGKSFSWRSNLTIHQRIHAADKSYKSHRGGKTIRDST", "length": 822, "header": "tr|A0AAA9S9S3-1|F1N5W2_BOVIN Computationally mapped isoform of Zinc finger protein 226 OS=Bos taurus OX=9913 GN=ZNF226 PE=3 SV=1 CANONICAL=F1N5W2-1" }, "locus": { "chromosome": "18", "start_pos": 52148271, "end_pos": 52135011, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000120752.2", "url": "https://www.ensembl.org/id/ENSBTAT00000120752.2" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000080674.1", "url": "https://www.ensembl.org/id/ENSBTAP00000080674.1" } ] } }, { "isoform_ac": "A0AAA9T3L9-1", "url": "https://www.uniprot.org/uniprotkb/A0AAA9T3L9/entry", "sequence": { "sequence": "MSVCGFVPAGDFSFVCLVKVSAKTLHFPGRREKMNMFMEAVTFKDVAVAFTEEELGLLDSAQRKLYQDVMVENFRNLVSVEENNQSELSAIQERGLHEELSCWQIWQQIANDLTRCQDSMINNCQLHKQGYSLHQVGSGLSIQISEDENYILNEKAGGPGDTGNPRFASLRARDSWRKSSLTESQNYQNRYQEISTQSKLCRCKADVDSIGRISYHLDDRGVHKNEKSYCHNDYRKDSTVSTLDQNSMIHTGQKPYQCNECKRTFTSLSTFDLHQQLHSKETSHVCDECGKGFRYSSVLHIHQRVHIGEECSVFAECGKEFHQSSQLQTHQKVHSIKKPFTCEECGKGFSRRSALSIHCKVHTGEKPYTCEECGRAFSQASHLQDHQRVHTGEKPFICDACGKSFSRNSHLQSHQRVHTGEKPYKCEECGKGFICSSNLYIHQRVHTGEKPYKCEECGKGFSRPSSLQAHQGIHTGEKSYVCNVCGKGFTLSSNLQAHQRVHTGEKPYKCEECGKNFRRNSHYQVHLVVHTGEKPYKCEVCGKGFSQSSYLQIHQKAHSVEKPYKCKECGQGFNQNSRLQIHQLIHTGEKPYKCEECGKGFSRRADLKIHCRIHTGEKPYNCEECGKVFRQASNLLAHQRVHSGEKPFKCEECGKSFGRSSHLQAHQKVHTGEKPYKCEECGKGFKWSLNLDMHQRVHTGEKPYKCGECGKHFSQASSLQLHQSVHTGEKPYRCDVCGKVFSRSSQLQSHQRVHTGEKPYKCEMCGKSFSWRSNLTIHQRIHAADKSYKSHRGGKTIRDST", "length": 801, "header": "tr|A0AAA9T3L9-1|F1N5W2_BOVIN Computationally mapped isoform of Zinc finger protein 226 OS=Bos taurus OX=9913 GN=ZNF226 PE=3 SV=1 CANONICAL=F1N5W2-1" }, "locus": { "chromosome": "18", "start_pos": 52148271, "end_pos": 52138108, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000129675.2", "url": "https://www.ensembl.org/id/ENSBTAT00000129675.2" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000091236.1", "url": "https://www.ensembl.org/id/ENSBTAP00000091236.1" } ] } }, { "isoform_ac": "A0AAA9TBU5-1", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TBU5/entry", "sequence": { "sequence": "MWNQTLHFPGRREKMNMFMEAVTFKDVAVAFTEEELGLLDSAQRKLYQDVMVENFRNLVSVEENNQSELSAIQERGLHEELSCWQIWQQIANDLTRCQDSMINNCQLHKQGYSLHQVGSGLSIQISEDENYILNEKAGGPGDTGNPRFASLRARDSWRKSSLTESQNYQNRYQEISTQSKLCRCKADVDSIGRISYHLDDRGVHKNEKSYCHNDYRKDSTVSTLDQNSMIHTGQKPYQCNECKRTFTSLSTFDLHQQLHSKETSHVCDECGKGFRYSSVLHIHQRVHIGEECSVFAECGKEFHQSSQLQTHQKVHSIKKPFTCEECGKGFSRRSALSIHCKVHTGEKPYTCEECGRAFSQASHLQDHQRVHTGEKPFICDACGKSFSRNSHLQSHQRVHTGEKPYKCEECGKGFICSSNLYIHQRVHTGEKPYKCEECGKGFSRPSSLQAHQGIHTGEKSYVCNVCGKGFTLSSNLQAHQRVHTGEKPYKCEECGKNFRRNSHYQVHLVVHTGEKPYKCEVCGKGFSQSSYLQIHQKAHSVEKPYKCKECGQGFNQNSRLQIHQLIHTGEKPYKCEECGKGFSRRADLKIHCRIHTGEKPYNCEECGKVFRQASNLLAHQRVHSGEKPFKCEECGKSFGRSSHLQAHQKVHTGEKPYKCEECGKGFKWSLNLDMHQRVHTGEKPYKCGECGKHFSQASSLQLHQSVHTGEKPYRCDVCGKVFSRSSQLQSHQRVHTGEKPYKCEMCGKSFSWRSNLTIHQRIHAADKSYKSHRGGKTIRDST", "length": 782, "header": "tr|A0AAA9TBU5-1|F1N5W2_BOVIN Computationally mapped isoform of Zinc finger protein 226 OS=Bos taurus OX=9913 GN=ZNF226 PE=3 SV=1 CANONICAL=F1N5W2-1" }, "locus": { "chromosome": "18", "start_pos": 52148271, "end_pos": 52133131, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000116801.2", "url": "https://www.ensembl.org/id/ENSBTAT00000116801.2" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000094327.1", "url": "https://www.ensembl.org/id/ENSBTAP00000094327.1" } ] } }, { "isoform_ac": "A0AAA9TLB6-1", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TLB6/entry", "sequence": { "sequence": "MKDSALPWKEREDEHVHEENNQSELSAIQERGLHEELSCWQIWQQIANDLTRCQDSMINNCQLHKQGYSLHQVGSGLSIQISEDENYILNEKAGGPGDTGNPRFASLRARDSWRKSSLTESQNYQNRYQEISTQSKLCRCKADVDSIGRISYHLDDRGVHKNEKSYCHNDYRKDSTVSTLDQNSMIHTGQKPYQCNECKRTFTSLSTFDLHQQLHSKETSHVCDECGKGFRYSSVLHIHQRVHIGEECSVFAECGKEFHQSSQLQTHQKVHSIKKPFTCEECGKGFSRRSALSIHCKVHTGEKPYTCEECGRAFSQASHLQDHQRVHTGEKPFICDACGKSFSRNSHLQSHQRVHTGEKPYKCEECGKGFICSSNLYIHQRVHTGEKPYKCEECGKGFSRPSSLQAHQGIHTGEKSYVCNVCGKGFTLSSNLQAHQRVHTGEKPYKCEECGKNFRRNSHYQVHLVVHTGEKPYKCEVCGKGFSQSSYLQIHQKAHSVEKPYKCKECGQGFNQNSRLQIHQLIHTGEKPYKCEECGKGFSRRADLKIHCRIHTGEKPYNCEECGKVFRQASNLLAHQRVHSGEKPFKCEECGKSFGRSSHLQAHQKVHTGEKPYKCEECGKGFKWSLNLDMHQRVHTGEKPYKCGECGKHFSQASSLQLHQSVHTGEKPYRCDVCGKVFSRSSQLQSHQRVHTGEKPYKCEMCGKSFSWRSNLTIHQRIHAADKSYKSHRGGKTIRDST", "length": 738, "header": "tr|A0AAA9TLB6-1|F1N5W2_BOVIN Computationally mapped isoform of Zinc finger protein 226 OS=Bos taurus OX=9913 GN=ZNF226 PE=3 SV=2 CANONICAL=F1N5W2-1" }, "locus": { "chromosome": "18", "start_pos": 52148271, "end_pos": 52134715, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000118015.2", "url": "https://www.ensembl.org/id/ENSBTAT00000118015.2" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000097993.2", "url": "https://www.ensembl.org/id/ENSBTAP00000097993.2" } ] } }, { "isoform_ac": "A0AAA9TSC7-1", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TSC7/entry", "sequence": { "sequence": "MIVTVPWSLKLRSKSFILMNTFPSHWLCASLLICDCQAAAPRNIPVIKELRLFELTEARTPMPHWCPGKEAVRTLHFPGRREKMNMFMEAVTFKDVAVAFTEEELGLLDSAQRKLYQDVMVENFRNLVSVEENNQSELSAIQERGLHEELSCWQIWQQIANDLTRCQDSMINNCQLHKQGYSLHQVGSGLSIQISEDENYILNEKAGGPGDTGNPRFASLRARDSWRKSSLTESQNYQNRYQEISTQSKLCRCKADVDSIGRISYHLDDRGVHKNEKSYCHNDYRKDSTVSTLDQNSMIHTGQKPYQCNECKRTFTSLSTFDLHQQLHSKETSHVCDECGKGFRYSSVLHIHQRVHIGEECSVFAECGKEFHQSSQLQTHQKVHSIKKPFTCEECGKGFSRRSALSIHCKVHTGEKPYTCEECGRAFSQASHLQDHQRVHTGEKPFICDACGKSFSRNSHLQSHQRVHTGEKPYKCEECGKGFICSSNLYIHQRVHTGEKPYKCEECGKGFSRPSSLQAHQGIHTGEKSYVCNVCGKGFTLSSNLQAHQRVHTGEKPYKCEECGKNFRRNSHYQVHLVVHTGEKPYKCEVCGKGFSQSSYLQIHQKAHSVEKPYKCKECGQGFNQNSRLQIHQLIHTGEKPYKCEECGKGFSRRADLKIHCRIHTGEKPYNCEECGKVFRQASNLLAHQRVHSGEKPFKCEECGKSFGRSSHLQAHQKVHTGEKPYKCEECGKGFKWSLNLDMHQRVHTGEKPYKCGECGKHFSQASSLQLHQSVHTGEKPYRCDVCGKVFSRSSQLQSHQRVHTGEKPYKCEMCGKSFSWRSNLTIHQRIHAADKSYKSHRGGKTIRDST", "length": 851, "header": "tr|A0AAA9TSC7-1|F1N5W2_BOVIN Computationally mapped isoform of Zinc finger protein 226 OS=Bos taurus OX=9913 GN=ZNF226 PE=3 SV=1 CANONICAL=F1N5W2-1" }, "locus": { "chromosome": "18", "start_pos": 52148271, "end_pos": 52134435, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000112843.2", "url": "https://www.ensembl.org/id/ENSBTAT00000112843.2" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000101504.1", "url": "https://www.ensembl.org/id/ENSBTAP00000101504.1" } ] } }, { "isoform_ac": "A0ABI0NN04-1", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NN04/entry", "sequence": { "sequence": "MNMFMEAVTFKDVAVAFTEEELGLLDSAQRKLYQDVMVENFRNLVSVEENNQSELSAIQERGLHEELSCWQIWQQIANDLTRCQDSMINNCQLHKQGYSLHQVGSGLSIQISEDENYILNEKAGGPGDTGNPRFASLRARDSWRKSSLTESQNYQNRYQEISTQSKLCRCKADVDSIGRISYHLDDRGVHKNEKSYCHNDYRKDSTVSTLDQNSMIHTGQKPYQCNECKRTFTSLSTFDLHQQLHSKETSHVCDECGKGFRYSSVLHIHQRVHIGEECSVFAECGKEFHQSSQLQTHQKVHSIKKPFTCEECGKGFSRRSALSIHCKVHTGEKPYTCEECGRAFSQASHLQDHQRVHTGEKPFICDACGKSFSRNSHLQSHQRVHTGEKPYKCEECGKGFICSSNLYIHQRVHTGEKPYKCEECGKGFSRPSSLQAHQGIHTGEKSYVCNVCGKGFTLSSNLQAHQRVHTGEKPYKCEECGKNFRRNSHYQVHLVVHTGEKPYKCEVCGKGFSQSSYLQIHQKAHSVEKPYKCKECGQGFNQNSRLQIHQLIHTGEKPYKCEECGKGFSRRADLKIHCRIHTGEKPYNCEECGKVFRQASNLLAHQRVHSGEKPFKCEECGKSFGRSSHLQAHQKVHTGEKPYKCEECGKGFKWSLNLDMHQRVHTGEKPYKCGECGKHFSQASSLQLHQSVHTGEKPYRCDVCGKVFSRSSQLQSHQRVHTGEKPYKCEMCGKSFSWRSNLTIHQRIHAADKSYKSHRGGKTIRDST", "length": 768, "header": "tr|A0ABI0NN04-1|A0ABI0NN04_BOVIN Computationally mapped isoform of Zinc finger protein 226 OS=Bos taurus OX=9913 GN=ZNF226 PE=3 SV=1 CANONICAL=F1N5W2-1" }, "locus": { "chromosome": "18", "start_pos": 52148271, "end_pos": 52139261, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000140288.1", "url": "https://www.ensembl.org/id/ENSBTAT00000140288.1" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000107053.1", "url": "https://www.ensembl.org/id/ENSBTAP00000107053.1" } ] } }, { "isoform_ac": "A0ABI0P719-1", "url": "https://www.uniprot.org/uniprotkb/A0ABI0P719/entry", "sequence": { "sequence": "MTTFKEAVTFTDVAVTFTEEEFRLLDSAQKKLYQDVMLENFRNLVSVGCHPFRHDIFHLEKEKRLWVVKTATQREGKSEEKIQSEMETISEVGPHEELSCWQIWRHIASDLTRCQDSRIKCSEFHQQCDSPGQNGAGLSVIHTGQIPSQCNECTKSFDDLSNFDLHQQIHSGEKSHTCCECGKSFCYSSALRIHQRVHSGEKRYKCDECGKEFSQSSQLQIHQKVHTVEKPFRCEQCGKGFSRRSTLTVHCKLHTGDKPYTCDKCGRAFIHASHLQEHQRIHTGEKPFKCDICGKNFRRRSALNSHCMVHTGEKPYKCEECGKCFTCSSNLHIHQRVHTGEKPYKCEECSKCFVQPSQFQAHRRIHTGEKPYVCKVCGKGFIYSSSFQAHQGVHTGEKPYRCDECGKNFRMKIHYQVHLVVHTGEKPYKCEVCGKGFRQSSYLKIHQKAHSIEKPYKCEECGQGFNQNSRLQIHQLIHTGEKPYKCEECGKGFSRRADLKIHCRIHTGEKPYNCEECGKVFSQASHLLTHQRVHSGEKPFKCEECDKSFGRSSHLQAHQKVHTGEKPFKCEECGKGFKWSLNLDMHQRVHTGEKPYKCGECGKHFSQASSLQLHQSVHTGEKPYRCDLCGKHFSQASSLQLHQSVHTGEKPYRCDVCGKVFSRSSQLQSHQRVHTGEKPYKCEMCGKSFSWRSNLTIHQRIHAADKSYKSHRGGKTIRDST", "length": 721, "header": "tr|A0ABI0P719-1|A0ABI0P719_BOVIN Computationally mapped isoform of Zinc finger protein 226 OS=Bos taurus OX=9913 GN=ZNF226 PE=3 SV=1 CANONICAL=F1N5W2-1" }, "locus": { "chromosome": "18", "start_pos": 52148271, "end_pos": 52124314, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000149328.1", "url": "https://www.ensembl.org/id/ENSBTAT00000149328.1" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000107413.1", "url": "https://www.ensembl.org/id/ENSBTAP00000107413.1" } ] } }, { "isoform_ac": "F1N5W2-1", "url": "https://www.uniprot.org/uniprotkb/F1N5W2/entry", "sequence": { "sequence": "MTTFKEAVTFTDVAVTFTEEEFRLLDSAQKKLYQDVMLENFRNLVSVGCHPFRHDIFHLEKEKRLWVVKTATQREGKSEEKIQSEMETISEVGPHEELSCWQIWRHIASDLTRCQDSRIKCSEFHQQCDSPGQNGAGLSVIHTGQIPSQCNECTKSFDDLSNFDLHQQIHSGEKSHTCCECGKSFCYSSALRIHQRVHSGEKRYKCDECGKEFSQSSQLQIHQKVHTVEKPFRCEQCGKGFSRRSTLTVHCKLHTGDKPYTCDKCGRAFIHASHLQEHQRIHTGEKPFKCDICGKNFRRRSALNSHCMVHTGEKPYKCEECGKCFTCSSNLHIHQRVHTGEKPYKCEECSKCFVQPSQFQAHRRIHTGEKPYVCKVCGKGFIYSSSFQAHQGVHTGEKPYRCDECGKNFRMKIHYQVHLVVHTGEKPYKCEVCGKGFRQSSYLKIHQKAHSIEKPYKCEECGQGFNQNSRLQIHQLIHTGEKPYKCEECGKGFSRRADLKIHCRIHTGEKPYNCEECGKVFSQASHLLTHQRVHSGEKPFKCEECDKSFGRSSHLQAHQKVHTGEKPFKCEECGKGFKWSLNLDMHQRVHTGEKPYKCGECGKHFSQASSLQLHQSVHTGEKPYRTLHFPGRREKMNMFMEAVTFKDVAVAFTEEELGLLDSAQRKLYQDVMVENFRNLVSVEENNQSELSAIQERGLHEELSCWQIWQQIANDLTRCQDSMINNCQLHKQGYSLHQVGSGLSIQISEDENYILNEKAGGPGDTGNPRFASLRARDSWRKSSLTESQNYQNRYQEISTQSKLCRCKADVDSIGRISYHLDDRGVHKNEKSYCHNDYRKDSTVSTLDQNSMIHTGQKPYQCNECKRTFTSLSTFDLHQQLHSKETSHVCDECGKGFRYSSVLHIHQRVHIGEECSVFAECGKEFHQSSQLQTHQKVHSIKKPFTCEECGKGFSRRSALSIHCKVHTGEKPYTCEECGRAFSQASHLQDHQRVHTGEKPFICDACGKSFSRNSHLQSHQRVHTGEKPYKCEECGKGFICSSNLYIHQRVHTGEKPYKCEECGKGFSRPSSLQAHQGIHTGEKSYVCNVCGKGFTLSSNLQAHQRVHTGEKPYKCEECGKNFRRNSHYQVHLVVHTGEKPYKCEVCGKGFSQSSYLQIHQKAHSVEKPYKCKECGQGFNQNSRLQIHQLIHTGEKPYKCEECGKGFSRRADLKIHCRIHTGEKPYNCEECGKVFRQASNLLAHQRVHSGEKPFKCEECGKSFGRSSHLQAHQKVHTGEKPYKCEECGKGFKWSLNLDMHQRVHTGEKPYKCGECGKHFSQASSLQLHQSVHTGEKPYRCDVCGKVFSRSSQLQSHQRVHTGEKPYKCEMCGKSFSWRSNLTIHQRIHAADKSYKSHRGGKTIRDST", "length": 1403, "header": "tr|F1N5W2-1|F1N5W2_BOVIN Isoform 1 of Zinc finger protein 226 OS=Bos taurus OX=9913 GN=ZNF226 PE=3 SV=4 CANONICAL=F1N5W2-1" }, "locus": { "chromosome": "18", "start_pos": 52148271, "end_pos": 52124314, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000055214.5", "url": "https://www.ensembl.org/id/ENSBTAT00000055214.5" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000052336.4", "url": "https://www.ensembl.org/id/ENSBTAP00000052336.4" } ] } }, { "isoform_ac": "F6QSN7-1", "url": "https://www.uniprot.org/uniprotkb/F6QSN7/entry", "sequence": { "sequence": "MSPHGILGSVVQELRVVAGPSAPGRRRSSHLSLDDDVSGPLFTIHSNFPEMRLGPASPDLSFGEKEKQRLEAEDSALPWKEREDEHVHEENNQSELSAIQERGLHEELSCWQIWQQIANDLTRCQDSMINNCQLHKQGYSLHQVGSGLSIQISEDENYILNEKAGGPGDTGNPRFASLRARDSWRKSSLTESQNYQNRYQEISTQSKLCRCKADVDSIGRISYHLDDRGVHKNEKSYCHNDYRKDSTVSTLDQNSMIHTGQKPYQCNECKRTFTSLSTFDLHQQLHSKETSHVCDECGKGFRYSSVLHIHQRVHIGEECSVFAECGKEFHQSSQLQTHQKVHSIKKPFTCEECGKGFSRRSALSIHCKVHTGEKPYTCEECGRAFSQASHLQDHQRVHTGEKPFICDACGKSFSRNSHLQSHQRVHTGEKPYKCEECGKGFICSSNLYIHQRVHTGEKPYKCEECGKGFSRPSSLQAHQGIHTGEKSYVCNVCGKGFTLSSNLQAHQRVHTGEKPYKCEECGKNFRRNSHYQVHLVVHTGEKPYKCEVCGKGFSQSSYLQIHQKAHSVEKPYKCKECGQGFNQNSRLQIHQLIHTGEKPYKCEECGKGFSRRADLKIHCRIHTGEKPYNCEECGKVFRQASNLLAHQRVHSGEKPFKCEECGKSFGRSSHLQAHQKVHTGEKPYKCEECGKGFKWSLNLDMHQRVHTGEKPYKCGECGKHFSQASSLQLHQSVHTGEKPYRCDVCGKVFSRSSQLQSHQRVHTGEKPYKCEMCGKSFSWRSNLTIHQRIHAADKSYKSHRGGKTIRDST", "length": 809, "header": "tr|F6QSN7-1|F6QSN7_BOVIN Computationally mapped isoform of Zinc finger protein 226 OS=Bos taurus OX=9913 GN=ZNF226 PE=3 SV=1 CANONICAL=F1N5W2-1" }, "locus": { "chromosome": "18", "start_pos": 52148271, "end_pos": 52133604, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000037250.6", "url": "https://www.ensembl.org/id/ENSBTAT00000037250.6" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000037087.4", "url": "https://www.ensembl.org/id/ENSBTAP00000037087.4" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [ { "id": "bta:789006", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?bta:789006", "resource": "KEGG Pathway" }, { "id": "R-BTA-212436", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-BTA-212436", "resource": "Reactome", "description": "Generic Transcription Pathway" } ], "orthologs": [ { "uniprot_canonical_ac": "A0A5G2RGQ6-1", "protein_name": "Zinc finger protein 227", "gene_name": "ZNF226", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MINSCQFHKLTGDSPCQVGAGLSIHISGDENCILSEKMNGPSGIENPEFATLGVQNSWRKTSLTESQNYHYRHKPISMKNKLYQCKEDFENINWISHHLDGHREHKSENSYNHDDYGKDSIRLSAFQNSMIHTEQKPYQCDKCKKTFTSLSTFGLHEQLHSKEKTHMCSECGKGFCYSSVLHIHQRVHMGEKRSKCDECGKEFTQSSHLQTHQKVHTIKKPFKCEECGKGFSRRSALSVHCKVHTGEKPYTCEECGRAFSQASHLQDHHRVHTGEKPFKCDACGKSFSRNSHLQSHQRVHTGEKPYKCEECGRGFICSSNLYIHQRVHTGEKPYKCEECGKGFSRPSSLQAHQGIHTGEKSYLCNVCGKGFTLSSNLQAHQRVHTGEKPYKCDECGKSFRRNSHYQVHLVVHTGEKPYKCEVCGKGFSQSSYLQIHQKAHSIEKPYKCEECGQGFNQSSRLQIHQLIHTGEKPYKCEECGKGFSRRADLKIHCRIHTGEKPYNCEECGKVFRQASNLLAHQRVHSGEKPFKCEECGKSFGRSSHLQAHQKVHTGEKPYKCEECGKGFKWSLNLDMHQRVHTGEKPYKCGECGKHFSQASSLQLHQSVHTGEKPYRCDVCGKVFSRSSQLQSHQRVHTGEKPYKCETCGKSFSWRSNLTIHYRIHAGDKSYKTGRGGKTISSHRNKIL", "length": 687 }, "evidence": [ { "id": "F1N5W2", "url": "https://omabrowser.org/oma/group/F1N5W2/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "Q9NYT6-1", "protein_name": "Zinc finger protein 226", "gene_name": "ZNF226", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MNMFKEAVTFKDVAVAFTEEELGLLGPAQRKLYRDVMVENFRNLLSVGHPPFKQDVSPIERNEQLWIMTTATRRQGNLGEKNQSKLITVQDRESEEELSCWQIWQQIANDLTRCQDSMINNSQCHKQGDFPYQVGTELSIQISEDENYIVNKADGPNNTGNPEFPILRTQDSWRKTFLTESQRLNRDQQISIKNKLCQCKKGVDPIGWISHHDGHRVHKSEKSYRPNDYEKDNMKILTFDHNSMIHTGQKSYQCNECKKPFSDLSSFDLHQQLQSGEKSLTCVERGKGFCYSPVLPVHQKVHVGEKLKCDECGKEFSQGAHLQTHQKVHVIEKPYKCKQCGKGFSRRSALNVHCKVHTAEKPYNCEECGRAFSQASHLQDHQRLHTGEKPFKCDACGKSFSRNSHLQSHQRVHTGEKPYKCEECGKGFICSSNLYIHQRVHTGEKPYKCEECGKGFSRPSSLQAHQGVHTGEKSYICTVCGKGFTLSSNLQAHQRVHTGEKPYKCNECGKSFRRNSHYQVHLVVHTGEKPYKCEICGKGFSQSSYLQIHQKAHSIEKPFKCEECGQGFNQSSRLQIHQLIHTGEKPYKCEECGKGFSRRADLKIHCRIHTGEKPYNCEECGKVFRQASNLLAHQRVHSGEKPFKCEECGKSFGRSAHLQAHQKVHTGDKPYKCDECGKGFKWSLNLDMHQRVHTGEKPYKCGECGKYFSQASSLQLHQSVHTGEKPYKCDVCGKVFSRSSQLQSHQRVHTGEKPYKCEICGKSFSWRSNLTVHHRIHVGDKSYKSNRGGKNIRESTQEKKSIK", "length": 803 }, "evidence": [ { "id": "F1N5W2", "url": "https://omabrowser.org/oma/group/F1N5W2/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" } ], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 1, "go_terms": [ { "name": "nucleus", "id": "GO:0005634", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005634", "evidence": [ { "database": "UniProtKB", "id": "F1N5W2", "url": "https://www.uniprot.org/uniprotkb/F1N5W2" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 4, "go_terms": [ { "name": "DNA-templated transcription", "id": "GO:0006351", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006351", "evidence": [ { "database": "UniProtKB", "id": "F1N5W2", "url": "https://www.uniprot.org/uniprotkb/F1N5W2" } ], "pmid": "" }, { "name": "regulation of DNA-templated transcription", "id": "GO:0006355", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006355", "evidence": [ { "database": "UniProtKB", "id": "F1N5W2", "url": "https://www.uniprot.org/uniprotkb/F1N5W2" } ], "pmid": "" }, { "name": "negative regulation of DNA-templated transcription", "id": "GO:0045892", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0045892", "evidence": [ { "database": "UniProtKB", "id": "F1N5W2", "url": "https://www.uniprot.org/uniprotkb/F1N5W2" } ], "pmid": "" }, { "name": "negative regulation of transcription by RNA polymerase II", "id": "GO:0000122", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000122", "evidence": [ { "database": "UniProtKB", "id": "F1N5W2", "url": "https://www.uniprot.org/uniprotkb/F1N5W2" } ], "pmid": "" } ] }, { "name": "Molecular Function", "total": 4, "go_terms": [ { "name": "zinc ion binding", "id": "GO:0008270", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008270", "evidence": [ { "database": "UniProtKB", "id": "F1N5W2", "url": "https://www.uniprot.org/uniprotkb/F1N5W2" } ], "pmid": "" }, { "name": "sequence-specific DNA binding", "id": "GO:0043565", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0043565", "evidence": [ { "database": "UniProtKB", "id": "F1N5W2", "url": "https://www.uniprot.org/uniprotkb/F1N5W2" } ], "pmid": "" }, { "name": "RNA polymerase II cis-regulatory region sequence-specific DNA binding", "id": "GO:0000978", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000978", "evidence": [ { "database": "UniProtKB", "id": "F1N5W2", "url": "https://www.uniprot.org/uniprotkb/F1N5W2" } ], "pmid": "" }, { "name": "DNA-binding transcription factor activity, RNA polymerase II-specific", "id": "GO:0000981", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000981", "evidence": [ { "database": "UniProtKB", "id": "F1N5W2", "url": "https://www.uniprot.org/uniprotkb/F1N5W2" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 1376, "end_pos": 1378, "annotation": "n_glycosylation_sequon" }, { "start_pos": 686, "end_pos": 688, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [ { "pdb_id": "AF-F1N5W2-F1", "pdb_chain": "global", "start_pos": 1, "end_pos": 1403, 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"https://www.uniprot.org/uniprotkb/F6PUB3", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "F6PUB3-1", "url": "https://www.uniprot.org/uniprotkb/F6PUB3-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MAMLGKLLPLAGLYLVQGLPYGLQSGLLPVLLRARGLSLTRVGLAKALYAPWLFKLVWAPLVDKWGSSRGWLALSTAALGLLCGLLATLPPAGPGGAALPVPVAALLLLLNLAAAVQDVALDMLAVRLLEPAELGPGNTVQVVAYKLGAALASGGLLALLPALSWTLLFLLLAATYWLAAAAAWVAPALRQLPVPPPSAHPRPSLRLQQDLLAVPGTLWTAGFVLTYKLGEQGASGLFPLLLLDGGISTAELGLWNGVGAVLCSIAGSSLGGVLLARCWQPLPLLRSVLWFRLGGLAYQTALLFQLNSPRTNPVPGTVLRGATLLSLCLQHLLGGLVTTTTFTMMMRCSQLAPSALQATHYSLLATLELLGKLLVGTLAGALADSLGPRLCFSLFLALSATPMLYLGFAPSALA", "length": 414, "header": "tr|F6PUB3-1|F6PUB3_BOVIN Isoform 1 of Solute carrier family 33 member 2 OS=Bos taurus OX=9913 GN=MFSD3 PE=3 SV=2 CANONICAL=F6PUB3-1" }, "isoforms": [ { "isoform_ac": "A0A3Q1MYG7-1", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1MYG7/entry", "sequence": { "sequence": "MAMLGKLLPLAGLYLVQGLPYGLQSGLLPVLLRARGLSLTRVGLAKALYAPWLFKLVWAPLVDKWGSSRGWLALSTAALGLLCGLLATLPPAGPGGAALPVPVAALLLLLNLAAAVQDVALDMLAVRLLEPAELGPGNTVQVVAYKLGAALASGGLLALLPALSWTLLFLLLAATYWLAAAAAWVAPALRQLPVPPPSAHPRPSLRLQQDLLAVPGTLWTAGFVLTYKLGEQGASGLFPLLLLDGGISTAELGLWNGVGAVLCSIAGSSLGGVLLARCWQPLPLLRSVLWFRLGGLAYQTALLFQLNSPRTNPVPGTVLRGEGWATGGRSLGSWALLTHTLPGATLLSLCLQHLLGGLVTTTTFTMMMRCSQLAPSALQATHYSLLATLELLGKLLVGTLAGALADSLGPRLCFSLFLALSATPMLYLGFAPSALA", "length": 436, "header": "tr|A0A3Q1MYG7-1|F6PUB3_BOVIN Computationally mapped isoform of Solute carrier family 33 member 2 OS=Bos taurus OX=9913 GN=MFSD3 PE=3 SV=2 CANONICAL=F6PUB3-1" }, "locus": { "chromosome": "14", "start_pos": 436827, "end_pos": 435048, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000074427.2", "url": "https://www.ensembl.org/id/ENSBTAT00000074427.2" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000061106.2", "url": "https://www.ensembl.org/id/ENSBTAP00000061106.2" } ] } }, { "isoform_ac": "F6PUB3-1", "url": "https://www.uniprot.org/uniprotkb/F6PUB3/entry", "sequence": { "sequence": "MAMLGKLLPLAGLYLVQGLPYGLQSGLLPVLLRARGLSLTRVGLAKALYAPWLFKLVWAPLVDKWGSSRGWLALSTAALGLLCGLLATLPPAGPGGAALPVPVAALLLLLNLAAAVQDVALDMLAVRLLEPAELGPGNTVQVVAYKLGAALASGGLLALLPALSWTLLFLLLAATYWLAAAAAWVAPALRQLPVPPPSAHPRPSLRLQQDLLAVPGTLWTAGFVLTYKLGEQGASGLFPLLLLDGGISTAELGLWNGVGAVLCSIAGSSLGGVLLARCWQPLPLLRSVLWFRLGGLAYQTALLFQLNSPRTNPVPGTVLRGATLLSLCLQHLLGGLVTTTTFTMMMRCSQLAPSALQATHYSLLATLELLGKLLVGTLAGALADSLGPRLCFSLFLALSATPMLYLGFAPSALA", "length": 414, "header": "tr|F6PUB3-1|F6PUB3_BOVIN Isoform 1 of Solute carrier family 33 member 2 OS=Bos taurus OX=9913 GN=MFSD3 PE=3 SV=2 CANONICAL=F6PUB3-1" }, "locus": { "chromosome": "14", "start_pos": 436827, "end_pos": 435048, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000055203.4", "url": "https://www.ensembl.org/id/ENSBTAT00000055203.4" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000051160.4", "url": "https://www.ensembl.org/id/ENSBTAP00000051160.4" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [], "orthologs": [ { "uniprot_canonical_ac": "F1RSP6-1", "protein_name": "Solute carrier family 33 member 2", "gene_name": "MFSD3", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MHGKLLVLASLYLVQGLPYGLQSGLLPVLLRARGLSLTHVGLAKVLYAPWLFKLVWAPLVDARGSPRAWLTLSTAALGLLCGLLAALPPAEAGQSGLPLTVAGLLLLLNLAAAVQDVALDTLAMQLLEPAELGPGNTVQVVAYKLGAVLAGGGLLTLLPTLSWPLLFLLLAATYWLAAALAWAAPALQQLPAPQPSEPRRHTLHLQQHLLAVPGTLWMAGFVLSYKLGEQGTSSLFPLLLLDCGVSTPELGLWNGVGAVVCSIVGSSLGGALLARHRQPLPLLRSLLRFRLGGLACQTVLVFHLDAPGARVGPGTVLRGAALLSLCLQHFLGGLVTTTTFTLMMRCSQLAPSALQATHYSLLATLELLGKLLVGALAGALADSLGLRFCFFLFLALSATPMLCLGLAPSTLA", "length": 412 }, "evidence": [ { "id": "F6PUB3", "url": "https://omabrowser.org/oma/group/F6PUB3/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "Q4V8E5-1", "protein_name": "Solute carrier family 33 member 2", "gene_name": "Slc33a2", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MHGKLLPLAGLYLVQGLPYGLQSSLLPILLRARGLSLTRVGLTKGLYAPWLLKLAWAPLVDRRGTPRVWLTFSTVCLGLVCGLLAVLPPPQAGQTGLPTTVMGLLLLLNLGAAVQDVALDTLAVQLLEPKELGPGNTVQVVAYKLGSALAGGGLLVFFPTLSWPLLFLLLTATYWLAAALAWAAPALGRLSRPQVSEHTPHTSYLLQDLLAVPGTLWTAGFVLTYKMGEQGAGSLFPLLLLDHGASASDLGLWSGLGAATCSIAGSSLGGALLARHCSHPRQPLKLLRSVLQLRLGGLACQTALLLHLNTPGASLDPGTVMRGAALLSLCLQQFLGGVVTTATFTVMMHCSQLAPRALQATHYSFLATLELLGKLLPGTLAGVLADGLGPRLCFAAFLVLSALPVLDLRLAPSNLT", "length": 416 }, "evidence": [ { "id": "F6PUB3", "url": "https://omabrowser.org/oma/group/F6PUB3/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "Q5U419-1", "protein_name": "Solute carrier family 33 member 2", "gene_name": "Slc33a2", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MHGKLLPLAGLYLVQGLPYGLQSSLLPILLRARGLSLTRVGLTKGLYAPWLLKLAWAPLVDRRGTPRVWLTLSTLSLGLVCGLLAVLPPPQAGQTGLPTTVMGLLLLLNLGAAVQDVALDTLAVQLLEPKELGPGNTVQVVAYKLGSALAGGGLLVLFPTLSWPLLFLLLAATYWLAAALAWAAPALGRLPWPQASEHTPHSSYLLQDLLAVPGTLWTAGFVLTYKLGEQGAGSLFPLLLLDHGASASDLGLWSGLGAVTCSIAGSSLGGALLARHWQPLKLLKTVLQLRLGSLACQTALLFHLNSPGASVDPGTVMRGAVLLSLCLQQFFGGVVTTATFTVMMHCSQLAPRALQATHYSFLATLELLGKLLLGTLAGVLADSLGPHLCFAVFLVLSALPVLDLRLAPSNLT", "length": 412 }, "evidence": [ { "id": "F6PUB3", "url": "https://omabrowser.org/oma/group/F6PUB3/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q96ES6-1", "protein_name": "Solute carrier family 33 member 2", "gene_name": "SLC33A2", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MRGKLLPLAGLYLVQGLPYGLQSGLLPVLLRAGGLSLTRVGLAKVLYAPWLLKLAWAPLVDAQGSARAWVTRSTAGLGLVCGLLAGLPPPGAGQAGLPAAVAGLLLLLNLGAAMQDVALDALAVQLLEPAELGPGNTVQVVAYKLGAALAGGALLALLPTFSWPQLFLLLAATYWLAAALAWAAPALRRLPQQPPSEQRPHTAHLLRDVLAVPGTVWTAGFVLTYKLGEQGASSLFPLLLLDHGVSAPELGLWNGVGAVVCSIAGSSLGGTLLAKHWKLLPLLRSVLRFRLGGLACQTALVFHLDTLGASMDAGTILRGSALLSLCLQHFLGGLVTTVTFTGMMRCSQLAPRALQATHYSLLATLELLGKLLLGTLAGGLADGLGPHPCFLLLLILSAFPVLYLDLAPSTFL", "length": 412 }, "evidence": [ { "id": "F6PUB3", "url": "https://omabrowser.org/oma/group/F6PUB3/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" } ], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 1, "go_terms": [ { "name": "membrane", "id": "GO:0016020", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016020", "evidence": [ { "database": "UniProtKB", "id": "F6PUB3", "url": "https://www.uniprot.org/uniprotkb/F6PUB3" } ], "pmid": "" } ] }, { "name": "Molecular Function", "total": 1, "go_terms": [ { "name": "transmembrane 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] }, { "name": "TELO2-interacting protein 2 isoform X1", "type": "synonym", "evidence": [ { "id": "XP_005226105", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_005226105" } ] } ], "function": [], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Bos taurus", "taxid": 9913, "evidence": [ { "database": "UniProtKB", "id": "F6RG44", "url": "https://www.uniprot.org/uniprotkb/F6RG44" } ], "common_name": "Bovine", "glygen_name": "Bovine", "reference_species": "Bos taurus [9913]" } ], "gene": [ { "name": "TTI2", "url": "https://www.uniprot.org/uniprotkb/F6RG44", "locus": { "chromosome": "27", "start_pos": 29214139, "end_pos": 29225350, "strand": "+", "evidence": [ { "database": "Ensembl Gene", "id": "ENSBTAG00000015463", "url": "https://www.ensembl.org/id/ENSBTAG00000015463" } ] } } ], "crossref": [ { "id": "F6RG44", "url": "https://alphafold.ebi.ac.uk/entry/F6RG44", "database": "AlphaFoldDB", "categories": [] }, { "id": "535350", "url": "https://www.ncbi.nlm.nih.gov/gene/535350", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR016024", "url": "https://www.ebi.ac.uk/interpro/entry/IPR016024", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR018870", "url": "https://www.ebi.ac.uk/interpro/entry/IPR018870", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "PTHR32226", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR32226", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR32226:SF2", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR32226:SF2", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF10521", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF10521", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "XP_005226105", "url": 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"MEPHGPWESPPWEGSSLPGAWSSSALGQAFSQILHQFAGQESRRGKARSAALEDLAALLEAKECDRLFEGSDASLRGMPEMLGQVAKALGKYAAPAEEPEGRGDRHPDVAEKAAAVALLFLKLLRKVEAAKNSLVCPAWKTSLRPLAGPIYVFAVTHSLEQPWTSPRSQEVAGQVLALLLQVTECGSVAGFLHGENEDEKGRFTAIMGLLKPDLNKDSWKNNPATKYVFSWTLQKVTRPWLSQHLERTLPPSLLISDDYQTENKILGVHCLQHIVLNVPAADLLQYNRAQVLYHALFNHLYAREHHLIQAVLLCLLDLFPILEKAQHWKGDGARPTTHCDEVLQLILTHMEPEHRLLLRRTYSRNLPAFVKRLGILTVRHLKRLERVIIGYLEVYDGPEEEARLKILETLKLLLQYTWPSSRKMEDHFRIPRTPKFTQNLFRQVSCRLVVLLKALLKLICDVARDSSLTPECVKSALLEEATDCLILLDRCASGRVKGLLAKIPRSCEDSQVGNCIRRVQQLSEGAPCDTT", "length": 531, "header": "tr|F6RG44-1|F6RG44_BOVIN Isoform 1 of TELO2 interacting protein 2 OS=Bos taurus OX=9913 GN=TTI2 PE=3 SV=1 CANONICAL=F6RG44-1" }, "isoforms": [ { "isoform_ac": "A0A3Q1N5Y8-1", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1N5Y8/entry", "sequence": { "sequence": "MEPHGPWESPPWEGSSLPGAWSSSALGQAFSQILHQFAGQESRRGKARSAALEDLAALLEAKECDRLFEGSDASLRGMPEMLGQVAKALGKYAAPAEEPEGRGDRHPDVAEKAAAVALLFLKLLRKVEAAKNSLVCPAWKTSLRPLAGPIYVFAVTHSLEQPWTSPRSQEVAGQVLALLLQVTECGSVAGFLHGENEDEKGRFTAIMGLLKPDLNKDSWKNNPATKYVFSWTLQKVTRPWLSQHLERTLPPSLLISDDYQTENKILGVHCLQHIVLNVAVLLCLLDLFPILEKAQHWKGDGARPTTHCDEVLQLILTHMEPEHRLLLRRTYSRNLPAFVKRLGILTVRHLKRLERVIIGYLEVYDGPEEEARLKILETLKLLLQYTWPRVSCRLVVLLKALLKLICDVARDSSLTPECVKSALLEEATDCLILLDRCASGRVKGLLAKIPRSCEDSQVGNCIRRVQQLSEGAPCDTT", "length": 477, "header": "tr|A0A3Q1N5Y8-1|F6RG44_BOVIN Computationally mapped isoform of TELO2 interacting protein 2 OS=Bos taurus OX=9913 GN=TTI2 PE=3 SV=2 CANONICAL=F6RG44-1" }, "locus": { "chromosome": "27", "start_pos": 29225000, "end_pos": 29214248, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000076856.2", "url": "https://www.ensembl.org/id/ENSBTAT00000076856.2" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000065777.2", "url": "https://www.ensembl.org/id/ENSBTAP00000065777.2" } ] } }, { "isoform_ac": "A0AAA9T7D6-1", "url": "https://www.uniprot.org/uniprotkb/A0AAA9T7D6/entry", "sequence": { "sequence": "MEPHGPWESPPWEGSSLPGAWSSSALGQAFSQILHQFAGQESRRGKARSAALEDLAALLEAKECDRLFEGSDASLRGMPEMLGQVAKALGKYAAPAEEPEGRGDRHPDVAEKAAAVALLFLKLLRKVEAAKNSLVCPAWKTSLRPLAGPIYVFAVTHSLEQPWTSPRSQEVAGQVLALLLQVTECGSVAGFLHGENEDEKGRFTAIMGLLKPDLNKDSWKNNPATKYVFSWTLQKVTRPWLSQHLERTLPPSLLISDDYQTENKILGVHCLQHIVLNVPAADLLQYNRAQVLYHALFNHLYAREHHLIQAVLLCLLDLFPILEKAQHWKGDGARPTTHCDEVLQLILTHMEPEHRLLLRRTYSRNLPAFVKRLGILTVRHLKRLERVIIGYLEVYDGPEEEARLKILETLKLLLQYTWPRVSCRLVVLLKALLKLICDVARDSSLTPECVKSALLEEATDCLILLDRCASGRVKVRDSPPLGFG", "length": 484, "header": "tr|A0AAA9T7D6-1|F6RG44_BOVIN Computationally mapped isoform of TELO2 interacting protein 2 OS=Bos taurus OX=9913 GN=TTI2 PE=3 SV=1 CANONICAL=F6RG44-1" }, "locus": { "chromosome": "27", "start_pos": 29225000, "end_pos": 29215172, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000089342.1", "url": "https://www.ensembl.org/id/ENSBTAT00000089342.1" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000092517.1", "url": "https://www.ensembl.org/id/ENSBTAP00000092517.1" } ] } }, { "isoform_ac": "F6RG44-1", "url": "https://www.uniprot.org/uniprotkb/F6RG44/entry", "sequence": { "sequence": "MEPHGPWESPPWEGSSLPGAWSSSALGQAFSQILHQFAGQESRRGKARSAALEDLAALLEAKECDRLFEGSDASLRGMPEMLGQVAKALGKYAAPAEEPEGRGDRHPDVAEKAAAVALLFLKLLRKVEAAKNSLVCPAWKTSLRPLAGPIYVFAVTHSLEQPWTSPRSQEVAGQVLALLLQVTECGSVAGFLHGENEDEKGRFTAIMGLLKPDLNKDSWKNNPATKYVFSWTLQKVTRPWLSQHLERTLPPSLLISDDYQTENKILGVHCLQHIVLNVPAADLLQYNRAQVLYHALFNHLYAREHHLIQAVLLCLLDLFPILEKAQHWKGDGARPTTHCDEVLQLILTHMEPEHRLLLRRTYSRNLPAFVKRLGILTVRHLKRLERVIIGYLEVYDGPEEEARLKILETLKLLLQYTWPSSRKMEDHFRIPRTPKFTQNLFRQVSCRLVVLLKALLKLICDVARDSSLTPECVKSALLEEATDCLILLDRCASGRVKGLLAKIPRSCEDSQVGNCIRRVQQLSEGAPCDTT", "length": 531, "header": "tr|F6RG44-1|F6RG44_BOVIN Isoform 1 of TELO2 interacting protein 2 OS=Bos taurus OX=9913 GN=TTI2 PE=3 SV=1 CANONICAL=F6RG44-1" }, "locus": { "chromosome": "27", "start_pos": 29225000, "end_pos": 29214248, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000020547.7", "url": "https://www.ensembl.org/id/ENSBTAT00000020547.7" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000020547.6", "url": "https://www.ensembl.org/id/ENSBTAP00000020547.6" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [], "orthologs": [], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 1, "go_terms": [ { "name": "TTT Hsp90 cochaperone complex", "id": "GO:0110078", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0110078", "evidence": [ { "database": "UniProtKB", "id": "F6RG44", "url": "https://www.uniprot.org/uniprotkb/F6RG44" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], 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"Bovine", "glygen_name": "Bovine", "reference_species": "Bos taurus [9913]" } ], "gene": [ { "name": "PITPNM2", "url": "https://www.uniprot.org/uniprotkb/F1N662", "locus": { "chromosome": "17", "start_pos": 52553696, "end_pos": 52441179, "strand": "-", "evidence": [ { "database": "Ensembl Gene", "id": "ENSBTAG00000001597", "url": "https://www.ensembl.org/id/ENSBTAG00000001597" } ] } } ], "crossref": [ { "id": "F1N662", "url": "https://alphafold.ebi.ac.uk/entry/F1N662", "database": "AlphaFoldDB", "categories": [] }, { "id": "ENSBTAG00000001597", "url": "https://bgee.org/?page=gene&gene_id=ENSBTAG00000001597", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "cd08889", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd08889", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "523999", "url": "https://www.ncbi.nlm.nih.gov/gene/523999", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR001666", "url": "https://www.ebi.ac.uk/interpro/entry/IPR001666", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR004177", "url": "https://www.ebi.ac.uk/interpro/entry/IPR004177", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR023214", "url": "https://www.ebi.ac.uk/interpro/entry/IPR023214", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR023393", "url": "https://www.ebi.ac.uk/interpro/entry/IPR023393", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR031315", "url": "https://www.ebi.ac.uk/interpro/entry/IPR031315", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR036412", "url": "https://www.ebi.ac.uk/interpro/entry/IPR036412", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR055261", "url": "https://www.ebi.ac.uk/interpro/entry/IPR055261", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "bta:523999", "url": "https://www.genome.jp/dbget-bin/www_bget?bta:523999", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "CWGRTMT", "url": "https://omabrowser.org/oma/group/CWGRTMT/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "A0A3Q1MUM3", "url": "https://www.orthodb.org/?gene=A0A3Q1MUM3", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A3Q1N8M0", "url": "https://www.orthodb.org/?gene=A0A3Q1N8M0", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR10658", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR10658", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR10658:SF41", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR10658:SF41", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF02121", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF02121", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF02862", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF02862", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF24694", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF24694", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF24695", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF24695", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "R-BTA-1483226", "url": "https://www.reactome.org/PathwayBrowser/#R-BTA-1483226", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "XP_024833057", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_024833057", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A3Q1MUM3", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1MUM3", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A3Q1MUM3-1", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1MUM3-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A3Q1N8M0", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1N8M0", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A3Q1N8M0-1", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1N8M0-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "F1N662", "url": "https://www.uniprot.org/uniprotkb/F1N662", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "F1N662-1", "url": "https://www.uniprot.org/uniprotkb/F1N662-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MIIKEYRIPLPMTVEEYRIAQLYMIQKKSRNETHGEGSGVEILENRPYTDGPGGSGQYTHKVYHVGMHIPSWFRSILPKAALRVVEESWNAYPYTRTRFTCPFVEKFSIDIETFYKTDAGENPNVFSLSPVEKNQLTIDFIDIVKDPVPPNEYKTEEDPKLFHSTKTQRGPLSENWIEEYKQQVFPIMCAYKLCKVEFRYWGMQSKIERFIHDTGLRKVMVRAHRQAWCWQDEWYGLNMDNIRELEKEAQLMLSRKMAQFNEEDKGAAELAKNEAAQDQASGEPSQPSSSGGEPLAGRGLKKQWSTSSKSSRSSKRGASPSRHSISEWRMQSIARDSDESSDDEFFDAHEDLSDSEEMFPKDITKWNSNDLMDKIESPEPEDSQDGLYRQRAPEFRVASSVEQLNIIEDEVSPPLAAPPSKIHVLLLLLHGGTILDTGAGDPSSKQGDANTIATVFDTVMRVHYPSALGHLAIRLVPCPPICSDAFALVSDLSPYSHDEGCLSSSQDHIPLAALPLLATSSPQYQEAVATVIQRANLAYGDFIKSQEGVTFNGQVCLIGDCVGGILAFDALCCSNQPVSESQSSSRRGSVASVQDADLLSPGSTVNTAHGSNLESSRHLSRSNIDIPRSNGNEDPKRQLPRKRSDSSTYELDTIQQHQAFLSSLHASVLRNEPSSRRSSSSTMLDGAGAVGKFDFEVADLFLFGCPLGLVLALRKTVIPSLDVFQLRPACQQVYNLFHPADPSASRLEPLLERRFHTLPPFSIPRYQRYPLGDGCSTLLVETVQRNPELVLEGGPLAPLPPGDGFLETSIPVPALTSQDGPRPSPGCAESEALQAHNTVFQEHAAPSSPGSAPSTRGFRRASEISIASQVSGMAESYTASGIAQIAAKWWGQKRIDYALYCPDALTAFPTVALPHLFHASYWESTDVVSFLLRQVMRHDNSSILELDGKEVSVFTPSKPREKWQRKRTHVKLRNVTANHRINDAVANEDGPQVLTGRFMYGPLDMVTLTGEKVDVHIMMQPPSGEWLYLDTLVTNSSGRVSYTIPETHRLGVGVYPIKMVVRGDHTFADSYITVLPKGTEFVVFSIDGSFAASVSIMGSDPKVRAGAVDVVRHWQDLGYLIIYVTGRPDMQKQRVVAWLAQHNFPHGVVSFCDGLVHDPLRHKANFLKLLISELHLRVHAAYGSTKDVAVYSSISLSPMQIYIVGRPTKKLQQQCQFITDGYAAHLAQLKYNHRARPARNAATRMALRKGSFGLPGQGDFLRSRNHLLRTISAQPSGPGPRPHERTQSQADSEQRGQRSMSMAAGCWGRTLAGRPEPGPAAGPK", "length": 1324, "header": "tr|F1N662-1|F1N662_BOVIN Isoform 1 of Phosphatidylinositol transfer protein membrane associated 2 OS=Bos taurus OX=9913 GN=PITPNM2 PE=3 SV=4 CANONICAL=F1N662-1" }, "isoforms": [ { "isoform_ac": "A0A3Q1MUM3-1", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1MUM3/entry", "sequence": { "sequence": "MIIKEYRIPLPMTVEEYRIAQLYMIQKKSRNETHGEGSGVEILENRPYTDGPGGSGQYTHKVYHVGMHIPSWFRSILPKAALRVVEESWNAYPYTRTRFTCPFVEKFSIDIETFYKTDAGENPNVFSLSPVEKNQLTIDFIDIVKDPVPPNEYKTEEDPKLFHSTKTQRGPLSENWIEEYKQQVFPIMCAYKLCKVEFRYWGMQSKIERFIHDTGLRKVMVRAHRQAWCWQDEWYGLNMDNIRELEKEAQLMLSRKMAQFNEEDKGAAELAKNEAAQDQASGEPSQPSSSGGEPLAGRGLKKQWSTSSKSSRSSKRGASPSRHSISEWRMQSIARDSDESSDDEFFDAHEDLSDSEEMFPKDITKWNSNDLMDKIESPEPEDSQDGLYRQRAPEFRVASSVEQLNIIEDEVSPPLAAPPSKIHVLLLLLHGGTILDTGAGDPSSKQGDANTIATVFDTVMRVHYPSALGHLAIRLVPCPPICSDAFALVSDLSPYSHDEGCLSSSQDHIPLAALPLLATSSPQYQEAVATVIQRANLAYGDFIKSQEGVTFNGQVCLIGDCVGGILAFDALCCSNQPVSESQSSSRRGSVASVQDADLLSPGSTVNTAHGSNLESSRHLSRSNIDIPRSNGNEDPKRQLPRKRSDSSTYELDTIQQHQAFLSSLHASVLRNEPSSRRSSSSTMLDGAGAVGKFDFEVADLFLFGCPLGLVLALRKTVIPSLDVFQLRPACQQVYNLFHPADPSASRLEPLLERRFHTLPPFSIPRYQRYPLGDGCSTLLVETVQRNPELVLEGGPLAPLPPGDGFLETSIPVPALTSQDGPRPSPGCAESEALQAHNTVFQEHAAPSSPGSAPSTRGFRRASEISIASQVSGMAESYTASGIAQKAPALLSHTPSVRRLSLLALPHPAPSTLGKRERAPRLPDLDISEVAAKWWGQKRIDYALYCPDALTAFPTVALPHLFHASYWESTDVVSFLLRQVMRHDNSSILELDGKEVSVFTPSKPREKWQRKRTHVKLRNVTANHRINDAVANEDGPQVLTGRFMYGPLDMVTLTGEKVDVHIMMQPPSGEWLYLDTLVTNSSGRVSYTIPETHRLGVGVYPIKMVVRGDHTFADSYITVLPKGTEFVVFSIDGSFAASVSIMGSDPKVRAGAVDVVRHWQDLGYLIIYVTGRPDMQKQRVVAWLAQHNFPHGVVSFCDGLVHDPLRHKANFLKLLISELHLRVHAAYGSTKDVAVYSSISLSPMQIYIVGRPTKKLQQQCQFITDGYAAHLAQLKYNHRARPARNAATRMALRKGSFGLPGQGDFLRSRNHLLRTISAQPSGPGPRPHERTQSQADSEQRGQRSMSMAAGCWGRTLAGRPEPGPAAGPK", "length": 1368, "header": "tr|A0A3Q1MUM3-1|A0A3Q1MUM3_BOVIN Computationally mapped isoform of Phosphatidylinositol transfer protein membrane associated 2 OS=Bos taurus OX=9913 GN=PITPNM2 PE=3 SV=1 CANONICAL=F1N662-1" }, "locus": { "chromosome": "17", "start_pos": 52551003, "end_pos": 52516077, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000079883.2", "url": "https://www.ensembl.org/id/ENSBTAT00000079883.2" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000070419.1", "url": "https://www.ensembl.org/id/ENSBTAP00000070419.1" } ] } }, { "isoform_ac": "A0A3Q1N8M0-1", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1N8M0/entry", "sequence": { "sequence": "MIIKEYRIPLPMTVEEYRIAQLYMIQKKSRNETHGEGSGVEILENRPYTDGPGGSGQYTHKVYHVGMHIPSWFRSILPKAALRVVEESWNAYPYTRTRFTCPFVEKFSIDIETFYKTDAGENPNVFSLSPVEKNQLTIDFIDIVKDPVPPNEYKTEEDPKLFHSTKTQRGPLSENWIEEYKQQVFPIMCAYKLCKVEFRYWGMQSKIERFIHDTGLRKVMVRAHRQAWCWQDEWYGLNMDNIRELEKEAQLMLSRKMAQFNEEDKGAAELAKNEAAQDQASGEPSQPSSSGGEPLAGRGLKKQWSTSSKSSRSSKRGASPSRHSISEWRMQSIARDSDESSDDEFFDAHEDLSDSEEMFPKDITKWNSNDLMDKIESPEPEDSQDGLYRQRAPEFRVASSVEQLNIIEDEVSPPLAAPPSKIHVLLLLLHGGTILDTGAGDPSSKQGDANTIATVFDTVMRVHYPSALGHLAIRLVPCPPICSDAFALVSDLSPYSHDEGCLSSSQDHIPLAALPLLATSSPQYQEAVATVIQRANLAYGDFIKSQEGVTFNGQVCLIGDCVGGILAFDALCCSNQPVSESQSSSRRGSVASVQDADLLSPGSTVNTAHGSNLESSRHLSRSNIDIPRSNGNEDPKRQLPRKRSDSSTYELDTIQQHQAFLSSLHASVLRNEPSSRRSSSSTMLDGAGAVGKFDFEVADLFLFGCPLGLVLALRKTVIPSLDVFQLRPACQQVYNLFHPADPSASRLEPLLERRFHTLPPFSIPRYQRYPLGDGCSTLLAEALQAHNTVFQEHAAPSSPGSAPSTRGFRRASEISIASQVSGMAESYTASGIAQKAPALLSHTPSVRRLSLLALPHPAPSTLGKRERAPRLPDLDISEVAAKWWGQKRIDYALYCPDALTAFPTVALPHLFHASYWESTDVVSFLLRQVMRHDNSSILELDGKEVSVFTPSKPREKWQRKRTHVKLRNVTANHRINDAVANEDGPQVLTGRFMYGPLDMVTLTGEKVDVHIMMQPPSGEWLYLDTLVTNSSGRVSYTIPETHRLGVGVYPIKMVVRGDHTFADSYITVLPKGTEFVVFSIDGSFAASVSIMGSDPKVRAGAVDVVRHWQDLGYLIIYVTGRPDMQKQRVVAWLAQHNFPHGVVSFCDGLVHDPLRHKANFLKLLISELHLRVHAAYGSTKDVAVYSSISLSPMQIYIVGRPTKKLQQQCQFITDGYAAHLAQLKYNHRARPARNAATRMALRKGSFGLPGQGDFLRSRNHLLRTISAQPSGPGPRPHERTQSQADSEQRGQRSMSMAAGCWGRTLAGRPEPGPAAGPK", "length": 1318, "header": "tr|A0A3Q1N8M0-1|F1N662_BOVIN Computationally mapped isoform of Phosphatidylinositol transfer protein membrane associated 2 OS=Bos taurus OX=9913 GN=PITPNM2 PE=3 SV=1 CANONICAL=F1N662-1" }, "locus": { "chromosome": "17", "start_pos": 52551003, "end_pos": 52516077, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000067863.1", "url": "https://www.ensembl.org/id/ENSBTAT00000067863.1" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000068345.1", "url": "https://www.ensembl.org/id/ENSBTAP00000068345.1" } ] } }, { "isoform_ac": "F1N662-1", "url": "https://www.uniprot.org/uniprotkb/F1N662/entry", "sequence": { "sequence": "MIIKEYRIPLPMTVEEYRIAQLYMIQKKSRNETHGEGSGVEILENRPYTDGPGGSGQYTHKVYHVGMHIPSWFRSILPKAALRVVEESWNAYPYTRTRFTCPFVEKFSIDIETFYKTDAGENPNVFSLSPVEKNQLTIDFIDIVKDPVPPNEYKTEEDPKLFHSTKTQRGPLSENWIEEYKQQVFPIMCAYKLCKVEFRYWGMQSKIERFIHDTGLRKVMVRAHRQAWCWQDEWYGLNMDNIRELEKEAQLMLSRKMAQFNEEDKGAAELAKNEAAQDQASGEPSQPSSSGGEPLAGRGLKKQWSTSSKSSRSSKRGASPSRHSISEWRMQSIARDSDESSDDEFFDAHEDLSDSEEMFPKDITKWNSNDLMDKIESPEPEDSQDGLYRQRAPEFRVASSVEQLNIIEDEVSPPLAAPPSKIHVLLLLLHGGTILDTGAGDPSSKQGDANTIATVFDTVMRVHYPSALGHLAIRLVPCPPICSDAFALVSDLSPYSHDEGCLSSSQDHIPLAALPLLATSSPQYQEAVATVIQRANLAYGDFIKSQEGVTFNGQVCLIGDCVGGILAFDALCCSNQPVSESQSSSRRGSVASVQDADLLSPGSTVNTAHGSNLESSRHLSRSNIDIPRSNGNEDPKRQLPRKRSDSSTYELDTIQQHQAFLSSLHASVLRNEPSSRRSSSSTMLDGAGAVGKFDFEVADLFLFGCPLGLVLALRKTVIPSLDVFQLRPACQQVYNLFHPADPSASRLEPLLERRFHTLPPFSIPRYQRYPLGDGCSTLLVETVQRNPELVLEGGPLAPLPPGDGFLETSIPVPALTSQDGPRPSPGCAESEALQAHNTVFQEHAAPSSPGSAPSTRGFRRASEISIASQVSGMAESYTASGIAQIAAKWWGQKRIDYALYCPDALTAFPTVALPHLFHASYWESTDVVSFLLRQVMRHDNSSILELDGKEVSVFTPSKPREKWQRKRTHVKLRNVTANHRINDAVANEDGPQVLTGRFMYGPLDMVTLTGEKVDVHIMMQPPSGEWLYLDTLVTNSSGRVSYTIPETHRLGVGVYPIKMVVRGDHTFADSYITVLPKGTEFVVFSIDGSFAASVSIMGSDPKVRAGAVDVVRHWQDLGYLIIYVTGRPDMQKQRVVAWLAQHNFPHGVVSFCDGLVHDPLRHKANFLKLLISELHLRVHAAYGSTKDVAVYSSISLSPMQIYIVGRPTKKLQQQCQFITDGYAAHLAQLKYNHRARPARNAATRMALRKGSFGLPGQGDFLRSRNHLLRTISAQPSGPGPRPHERTQSQADSEQRGQRSMSMAAGCWGRTLAGRPEPGPAAGPK", "length": 1324, "header": "tr|F1N662-1|F1N662_BOVIN Isoform 1 of Phosphatidylinositol transfer protein membrane associated 2 OS=Bos taurus OX=9913 GN=PITPNM2 PE=3 SV=4 CANONICAL=F1N662-1" }, "locus": { "chromosome": "17", "start_pos": 52551003, "end_pos": 52516077, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000002094.7", "url": "https://www.ensembl.org/id/ENSBTAT00000002094.7" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000002094.7", "url": "https://www.ensembl.org/id/ENSBTAP00000002094.7" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [ { "id": "bta:523999", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?bta:523999", "resource": "KEGG Pathway" }, { "id": "R-BTA-1483226", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-BTA-1483226", "resource": "Reactome", "description": "Synthesis of PI" } ], "orthologs": [ { "uniprot_canonical_ac": "A0A8I6AUE0-1", "protein_name": "Phosphatidylinositol transfer protein, membrane-associated 2", "gene_name": "Pitpnm2", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MIIKEYRIPLPMTVEEYRIAQLYMIQKKSRNETYGQGSGVEILENRPYTDGPGGSGQYTHKVYHVGMHIPGWFRSILPKAALRVVEESWNAYPYTRTRFTCPFVEKFSIDIETFYKTDTGENNNVFNLSPVEKNQLITDIIDIVKDPVTPSEYKTEEDPKLFQSIKTRRGPLSENWIQEYKKRLLPIMCAYKLCKVEFRYWGMQSKIERFIHDTGLRRVMVRAHRQAWCWQDEWYGLTMEKIRELEKEVQLMLSRKMAQFSEEGPSELSKESTIKDQATGATPEPSSSNGESLGRGLKKQWSTSSKSSRSSKRGASPSRHSISEWRMQSIARDSDESSEEEFFDAQENLQHKEEMYTKDITKWSSNDLMDKMENPEPEESQDSLYHQSGSEFRVASSVEQLNTIEDEVSQPLATPPSKIHVLLLVLHGGTILDTGAGDPSSKQGDTNTITNVFDTVMRVHYPSALGHLAIRLVPCPPICADAFALVSNLSPYGHDEGCLSSSQDHIPLAALPLLATSSPQYQEAVATVIQRANLAYGDFIKSQEGVTFNGQVCLIGDCVGGILAFDALCYSGQPVSESQSSSRRGSVVSMQDADLLSPGILVNAAHCSGGSGGGSGGGSSLESSRHLSRSNIDIPRSNGTEDSRKQMPRKRSDSSTYELDTIQQHQAFLSSLHASVLRNEPSSRRSSSSTMLDGAGALGKFDFEIADLFLFGCPLGLVLALRKTVIPSLDVFQLRPACQQVYNLFHPADPSASRLEPLLERRFHTLPPFNIPRYQRYPLGDGCSTLLVETVQRNPELVLEGGPLAPLPHGDSFLETSIPVPALTWQDGPRQSLGCSESDALQTHNTVFQEHAAPSSPGTAPASRGFRRASEISIASQVSGMAESYTASGIAQKGPSSLNHTPSIRRLSLLALPPPSPTTQGPRARARQVSPNLERGPCLPDLDIGEVAAKWWGQKRIDYALYCPDALMAFPTVALPHLFHASYWESTDVVSFLLRQVMRHDSASILELDGKEVSVFTPSQPREKWQRKRTHVKLRNVAANHRINDAVANEDGPQVVTGRFMYGPLDMVTLTGEKVDVHIMTQPPSGEWLYLDTLVTNSSGRVSYTIPETHRLGVGVYPIKMVVRGDHTFADSYITVLPKGTEFVVFSIDGSFAASVSIMGSDPKVRAGAVDVVRHWQDLGYLIIYVTGRPDMQKQRVVAWLAQHNFPHGVVSFCDGLVHDPLRHKANFLKLLISELHLRAHAAYGSTKDVAVYNSISLSPMHIYIVGRPTKKLQQQCQFITDGYAAHLAQLKYNHRARPARNTATRMALRKGSFGLPGQGDFLRSRNHLLRTISAQPSGPSHRHDRTQTQMDLEQRGQRSMSMAASCWGRAMAGRLEPGAATGPK", "length": 1385 }, "evidence": [ { "id": "F1N662", "url": "https://omabrowser.org/oma/group/F1N662/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "Q6ZPQ6-1", "protein_name": "Membrane-associated phosphatidylinositol transfer protein 2", "gene_name": "Pitpnm2", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MIIKEYRIPLPMTVDEYRIAQLYMIQKKSRNETHGQGSGVEILENRPYTDGPGGSGQYTHKVYHVGMHIPGWFRSILPKAALRVVEESWNAYPYTRTRFTCPFVEKFSIDIETFYKTDTGENNNVFNLSPVEKSQLITDIIDIVKDPVPPSEYKTEEDPKLFQSVKTCRGPLSENWIQEYKKRLLPIMCAYKLCKVEFRYWGMQSKIERFIHDTGLRRVMVRAHRQAWCWQDEWYGLTMEKIRELEREVQLMLSRKMAQFSEEGPSELSKDSATKDQASGTTSDPGSKNGEPLGRGLKKQWSTSSKSSRSSKRGASPSRHSISEWRMQSIARDSDEGSEEEFFDAHENLYCTEEKQAKDMTKWNSNDLMDKMESPEPEESQDEIYQQSGSEFRVASSVEQLNIIEDEVSQPLAAPPSKIHVLLLVLHGGTILDTGAGDPSSKQGDTNTITNVFDTVMRVHYPSALGHLAIRLVPCPPICADAFALVSNLSPYGHDEGCLSSSQDHIPLAALPLLATSSPQYQEAVATVIQRANLAYGDFIKSQEGVTFNGQVCLIGDCVGGILAFDALCYSGQPVSESQSSSRRGSVVSMQDADLLSPGTLANAAHCSGGSGGGGSGGSSLESSRHLSRSNIDIPRSNGTEDSRRQLPRKRSDSSTYELDTIQQHQAFLSSLHASVLRNEPSSRRSSSSTMLDGAGALGKFDFEIADLFLFGCPLGLVLALRKTVIPSLDVFQLRPACQQVYNLFHPADPSASRLEPLLERRFHSLPPFSIPRYQRYPLGDGCSTLLADVLQTHNTVFQEHAAPSSPGTAPAGRGFRRASEISIASQVSGMAESYTASSIAQKGPSSLNHTPSIRRLSLLALPPPSPTTQGPRARARQVSPNLERAPCLPDLDIGEVAAKWWGQKRIDYALYCPDALTAFPTVALPHLFHASYWESTDVVSFLLRQVMRHDSSSILELDGKEVSVFTPSQPRERWQRKRTHVKLRNVAANHRINDAVANEDGPQVVTGRFMYGPLDMVTLTGEKVDVHIMTQPPSGEWLHLDTLVTNSSGRVSYTIPETHRLGVGVYPIKMVVRGDHTFADSYITVLPRGTEFVVFSIDGSFAASVSIMGSDPKVRAGAVDVVRHWQDLGYLIIYVTGRPDMQKQRVVAWLAQHNFPHGVVSFCDGLVHDPLRHKANFLKLLISELHLRAHAAYGSTKDVAVYNSISLSPMHIYIVGRPTKKLQQQCQFITDGYAAHLAQLKYNHRARPARNTATRMALRKGSFGLPGQSDFLRSRNHLLRTISAQPSGPSHRHDRTQTQMDSEQRGQRSMSVAASCWGRAMAGRLEPGAATGPK", "length": 1335 }, "evidence": [ { "id": "F1N662", "url": "https://omabrowser.org/oma/group/F1N662/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q9BZ72-1", "protein_name": "Membrane-associated phosphatidylinositol transfer protein 2", "gene_name": "PITPNM2", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MIIKEYRIPLPMTVEEYRIAQLYMIQKKSRNETYGEGSGVEILENRPYTDGPGGSGQYTHKVYHVGMHIPSWFRSILPKAALRVVEESWNAYPYTRTRFTCPFVEKFSIDIETFYKTDAGENPDVFNLSPVEKNQLTIDFIDIVKDPVPHNEYKTEEDPKLFQSTKTQRGPLSENWIEEYKKQVFPIMCAYKLCKVEFRYWGMQSKIERFIHDTGLRRVMVRAHRQAWCWQDEWYGLSMENIRELEKEAQLMLSRKMAQFNEDGEEATELVKHEAVSDQTSGEPPEPSSSNGEPLVGRGLKKQWSTSSKSSRSSKRGASPSRHSISEWRMQSIARDSDESSDDEFFDAHEDLSDTEEMFPKDITKWSSNDLMDKIESPEPEDTQDGLYRQGAPEFRVASSVEQLNIIEDEVSQPLAAPPSKIHVLLLVLHGGTILDTGAGDPSSKKGDANTIANVFDTVMRVHYPSALGRLAIRLVPCPPVCSDAFALVSNLSPYSHDEGCLSSSQDHIPLAALPLLATSSPQYQEAVATVIQRANLAYGDFIKSQEGMTFNGQVCLIGDCVGGILAFDALCYSNQPVSESQSSSRRGSVVSMQDNDLLSPGILMNAAHCCGGGGGGGGGGGSSGGGGSSGGSSLESSRHLSRSNVDIPRSNGTEDPKRQLPRKRSDSSTYELDTIQQHQAFLSSLHASVLRTEPCSRHSSSSTMLDGTGALGRFDFEITDLFLFGCPLGLVLALRKTVIPALDVFQLRPACQQVYNLFHPADPSASRLEPLLERRFHALPPFSVPRYQRYPLGDGCSTLLADVLQTHNAAFQEHGAPSSPGTAPASRGFRRASEISIASQVSGMAESYTASSIAQKAPDALSHTPSVRRLSLLALPAPSPTTPGPHPPARKASPGLERAPGLPELDIGEVAAKWWGQKRIDYALYCPDALTAFPTVALPHLFHASYWESTDVVSFLLRQVMRHDNSSILELDGKEVSVFTPSKPREKWQRKRTHVKLRNVTANHRINDALANEDGPQVLTGRFMYGPLDMVTLTGEKVDVHIMTQPPSGEWLYLDTLVTNNSGRVSYTIPESHRLGVGVYPIKMVVRGDHTFADSYITVLPKGTEFVVFSIDGSFAASVSIMGSDPKVRAGAVDVVRHWQDLGYLIIYVTGRPDMQKQRVVAWLAQHNFPHGVVSFCDGLVHDPLRHKANFLKLLISELHLRVHAAYGSTKDVAVYSAISLSPMQIYIVGRPTKKLQQQCQFITDGYAAHLAQLKYSHRARPARNTATRMALRKGSFGLPGQGDFLRSRNHLLRTISAQPSGPSHRHERTQSQADGEQRGQRSMSVAAGCWGRAMTGRLEPGAAAGPK", "length": 1349 }, "evidence": [ { "id": "F1N662", "url": "https://omabrowser.org/oma/group/F1N662/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" } ], "go_annotation": { "categories": [ { "name": "Molecular Function", "total": 8, "go_terms": [ { "name": "metal ion binding", "id": "GO:0046872", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0046872", "evidence": [ { "database": "UniProtKB", "id": "F1N662", "url": "https://www.uniprot.org/uniprotkb/F1N662" } ], "pmid": "" }, { "name": "phospholipid transporter activity", "id": "GO:0005548", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005548", "evidence": [ { "database": "UniProtKB", "id": "F1N662", "url": "https://www.uniprot.org/uniprotkb/F1N662" } ], "pmid": "" }, { "name": "calcium ion binding", "id": "GO:0005509", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005509", "evidence": [ { "database": "UniProtKB", "id": "F1N662", "url": "https://www.uniprot.org/uniprotkb/F1N662" } ], "pmid": "" }, { "name": "receptor tyrosine kinase binding", "id": "GO:0030971", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030971", "evidence": [ { "database": "UniProtKB", "id": "F1N662", "url": "https://www.uniprot.org/uniprotkb/F1N662" } ], "pmid": "" }, { "name": "phosphatidylcholine binding", "id": "GO:0031210", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0031210", "evidence": [ { "database": "UniProtKB", "id": "F1N662", "url": "https://www.uniprot.org/uniprotkb/F1N662" } ], "pmid": "" }, { "name": "phosphatidylinositol binding", "id": "GO:0035091", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0035091", "evidence": [ { "database": "UniProtKB", "id": "F1N662", "url": "https://www.uniprot.org/uniprotkb/F1N662" } ], "pmid": "" }, { "name": "phosphatidylinositol transfer activity", "id": "GO:0008526", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008526", "evidence": [ { "database": "UniProtKB", "id": "F1N662", "url": "https://www.uniprot.org/uniprotkb/F1N662" } ], "pmid": "" }, { "name": "phosphatidylcholine transporter activity", "id": "GO:0008525", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008525", "evidence": [ { "database": "UniProtKB", "id": "F1N662", "url": "https://www.uniprot.org/uniprotkb/F1N662" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 2, "go_terms": [ { "name": "endomembrane system", "id": "GO:0012505", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0012505", "evidence": [ { "database": "UniProtKB", "id": "F1N662", "url": "https://www.uniprot.org/uniprotkb/F1N662" } ], "pmid": "" }, { "name": "cytoplasm", "id": "GO:0005737", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005737", "evidence": [ { "database": "UniProtKB", "id": "F1N662", "url": "https://www.uniprot.org/uniprotkb/F1N662" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 1035, "end_pos": 1037, "annotation": "n_glycosylation_sequon" }, { "start_pos": 31, "end_pos": 33, "annotation": "n_glycosylation_sequon" }, { "start_pos": 940, "end_pos": 942, "annotation": "n_glycosylation_sequon" }, { "start_pos": 974, "end_pos": 976, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "F1N662", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1N662" }, { "id": "PS51043", "database": "PROSITE", "url": "https://prosite.expasy.org/PS51043" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "DDHD", "eco_id": "ECO_0000259", "start_pos": 693, "end_pos": 937, "start_aa": "Phe", "end_aa": "Arg", "glycosite_overlap": [] } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" }, { "name": "homologset.oma", "label": "OMA Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 1035, "end_pos": 1037 }, { "start_pos": 31, "end_pos": 33 }, { "start_pos": 940, "end_pos": 942 }, { "start_pos": 974, "end_pos": 976 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ], "tool_support": { "graph_view": "yes" } }, { "uniprot_canonical_ac": "F1N5A3-1", "uniprot_ac": "F1N5A3", "uniprot_id": "F1N5A3_BOVIN", "mass": { "chemical_mass": 93686.0, "monoisotopic_mass": 93686.0 }, "refseq": {}, "gene_names": [], "protein_names": [ { "name": "PNN interacting serine and arginine rich protein", "type": "synonym", "evidence": [ { "id": "F1N5A3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1N5A3/entry#names_and_taxonomy" } ] } ], "function": [], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Bos taurus", "taxid": 9913, "evidence": [ { "database": "UniProtKB", "id": "F1N5A3", "url": "https://www.uniprot.org/uniprotkb/F1N5A3" } ], "common_name": "Bovine", "glygen_name": "Bovine", "reference_species": "Bos taurus [9913]" } ], "gene": [ { "name": "", "url": "https://www.uniprot.org/uniprotkb/F1N5A3", "locus": {} } ], "crossref": [ { "id": "F1N5A3", "url": "https://alphafold.ebi.ac.uk/entry/F1N5A3", "database": "AlphaFoldDB", "categories": [] }, { "id": "ENSBTAG00000019730", "url": "https://bgee.org/?page=gene&gene_id=ENSBTAG00000019730", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "IPR031937", "url": "https://www.ebi.ac.uk/interpro/entry/IPR031937", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "QFNGKRP", "url": "https://omabrowser.org/oma/group/QFNGKRP/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "PTHR31518", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR31518", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF15996", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF15996", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "A0A3Q1NBW7", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1NBW7", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A3Q1NBW7-1", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1NBW7-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "F1N5A3", "url": "https://www.uniprot.org/uniprotkb/F1N5A3", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "F1N5A3-1", "url": "https://www.uniprot.org/uniprotkb/F1N5A3-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MWDQGGQPWQQWPLNQQQWMQSFQHQQDPSQIDWAALAQAWIAQREASGQQSMVEQPPGMMPNGQDMSTMESGPNNHGNFQGDSNFNRMWQPEWGMHQQPPHPPPDQPWMPPTPGPMDIVPPSEDSNSQDSGEFAPDNRHIFNQNNHNFGGPPDNFAVGPVNQFDYQHGAAFGPPQGGFHPPYWQPGPPGPPAPPQNRRERPSSFRDRQRSPIALPVKQEPPQIDAVKRRTLPAWIREGLEKMEREKQKKLEKERMEQQRSQLSKKEKKATDDAEGGDGPRLPQRSKFDSDEEDEDTENVEAASSGKVTRSPSPVPQEEQSEPEMTEEEKEYQMMLLTKMLLTEILLDVTDEEIYYIAKDAHRKATKAPAKQLAQSSALASLTGLGGLGGYGSGDSEDERSNRGSESSDTDDEELRHRIRQKQEAFWRKEKEQQLLHDKQMEEEKQQSERVTKEMNEFIHKEQNSLSLLEAREADGDVVNEKKRTSNETTSVLEPKREHKEKEKQGRSRSGSSSSGSSSSNSRSSSTSSSVSSSSYSSSSGSSRTSSRSSSPKRKKRHSRSRSPTIKARRSRSRSYSRRIKIESNRARVKIRDRRRSNRNSIERERRRNRSPSRERRRSRSRSRDRRTNRSSRSRSRDRRKIDDLRGSLSGSSHKHKGEVKEQERRKERSRSIDKDRKKKDKEREREQDKRKEKQKREEKDFKFSSQDDRLKRKRESERTFSRSGSISVKIIRHDSRQDSKKSTTKDSKKHSGSDSSGRSSSESPGSSKEKKVKKPKHSRSRSMEKSQRSGKKASRKHKSKSRSRSTTPPRRKR", "length": 814, "header": "tr|F1N5A3-1|F1N5A3_BOVIN Isoform 1 of PNN interacting serine and arginine rich protein OS=Bos taurus OX=9913 GN= PE=4 SV=3 CANONICAL=F1N5A3-1" }, "isoforms": [ { "isoform_ac": "A0A3Q1NBW7-1", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1NBW7/entry", "sequence": { "sequence": "MWDQGGQPWQQWPLNQQQWMQSFQHQQDPSQIDWAALAQAWIAQREASGQQSMVEQPPGMMPNGQDMSTMESGPNNHGNFQGDSNFNRMWQPEWGMHQQPPHPPPDQPWMPPTPGPMDIVPPSEDSNSQDSGEFAPDNRHIFNQNNHNFGGPPDNFAVGPVNQFDYQHGAAFGPPQGGFHPPYWQPGPPGPPAPPQNRRERPSSFRDRQRSPIALPVKQEPPQIDAVKRRTLPAWIREGLEKMEREKQKKLEKERMEQQRSQLSKKEKKATDDAEGGDGPRLPQRSKFDSDEEDEDTENVEAASSGKVTRSPSPVPQEEQSEPEMTEEEKEYQMMLLTKMLLTEILLDVTDEEIYYIAKDAHRKATKAPAKQLAQSSALASLTGLGGLGGYGSGDSEDERSNRGSESSDTDDEELRHRIRQKQEAFWRKEKEQQLLHDKQMEEEKQQSERVTKEMNEFIHKEQNSLSLLEAREADGDVVNEKKRTSNETTSVLEPKREHKEKEKQGRSRSGSSSSGSSSSNSRSSSTSSSVSSSSYSSSSGSSRTSSRSSSPKRKKRHSRSRSPTIKARRSRSRSYSRRIKIESNRARVKIRDRRRSNRNSIERERRRNRSPSRERRRSRSRSRDRRTNRSSRSRSRDRRKIDDLRGSLSGSSHKHKGEVKEQERRKERSRSIDKDRKKKDKEREREQDKRKEKQKREEKDFKFSSQDDRLKRKRESERTFSRSGSISVKIIRHDSRQDSKKSTTKDSKKHSGSDSSGRSSSESPGSSKEKKVKKPKHSRSRSMEKSQRSGKKASRKHKSKSRSR", "length": 805, "header": "tr|A0A3Q1NBW7-1|F1N5A3_BOVIN Computationally mapped isoform of PNN interacting serine and arginine rich protein OS=Bos taurus OX=9913 GN= PE=4 SV=2 CANONICAL=F1N5A3-1" }, "locus": { "chromosome": "9", "start_pos": 50372535, "end_pos": 50357695, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000086229.3", "url": "https://www.ensembl.org/id/ENSBTAT00000086229.3" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000068846.2", "url": "https://www.ensembl.org/id/ENSBTAP00000068846.2" } ] } }, { "isoform_ac": "F1N5A3-1", "url": "https://www.uniprot.org/uniprotkb/F1N5A3/entry", "sequence": { "sequence": "MWDQGGQPWQQWPLNQQQWMQSFQHQQDPSQIDWAALAQAWIAQREASGQQSMVEQPPGMMPNGQDMSTMESGPNNHGNFQGDSNFNRMWQPEWGMHQQPPHPPPDQPWMPPTPGPMDIVPPSEDSNSQDSGEFAPDNRHIFNQNNHNFGGPPDNFAVGPVNQFDYQHGAAFGPPQGGFHPPYWQPGPPGPPAPPQNRRERPSSFRDRQRSPIALPVKQEPPQIDAVKRRTLPAWIREGLEKMEREKQKKLEKERMEQQRSQLSKKEKKATDDAEGGDGPRLPQRSKFDSDEEDEDTENVEAASSGKVTRSPSPVPQEEQSEPEMTEEEKEYQMMLLTKMLLTEILLDVTDEEIYYIAKDAHRKATKAPAKQLAQSSALASLTGLGGLGGYGSGDSEDERSNRGSESSDTDDEELRHRIRQKQEAFWRKEKEQQLLHDKQMEEEKQQSERVTKEMNEFIHKEQNSLSLLEAREADGDVVNEKKRTSNETTSVLEPKREHKEKEKQGRSRSGSSSSGSSSSNSRSSSTSSSVSSSSYSSSSGSSRTSSRSSSPKRKKRHSRSRSPTIKARRSRSRSYSRRIKIESNRARVKIRDRRRSNRNSIERERRRNRSPSRERRRSRSRSRDRRTNRSSRSRSRDRRKIDDLRGSLSGSSHKHKGEVKEQERRKERSRSIDKDRKKKDKEREREQDKRKEKQKREEKDFKFSSQDDRLKRKRESERTFSRSGSISVKIIRHDSRQDSKKSTTKDSKKHSGSDSSGRSSSESPGSSKEKKVKKPKHSRSRSMEKSQRSGKKASRKHKSKSRSRSTTPPRRKR", "length": 814, "header": "tr|F1N5A3-1|F1N5A3_BOVIN Isoform 1 of PNN interacting serine and arginine rich protein OS=Bos taurus OX=9913 GN= PE=4 SV=3 CANONICAL=F1N5A3-1" }, "locus": { "chromosome": "9", "start_pos": 50372808, "end_pos": 50357695, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000026293.8", "url": "https://www.ensembl.org/id/ENSBTAT00000026293.8" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000026293.6", "url": "https://www.ensembl.org/id/ENSBTAP00000026293.6" } ] } } ], "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "other", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 113, "start_aa": "Thr", "end_pos": 113, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr113", "evidence": [ { "id": "", "database": "GlyGen", "url": "https://data.glygen.org/" } ], "filter_code": "000000000000000010000.00000000001000.0.01000" } ], "phosphorylation": [], "glycation": [], "keywords": [ "glycoprotein", "glycoprotein_predicted" ], "publication": [], "pathway": [], "orthologs": [ { "uniprot_canonical_ac": "A0A8V0XJC7-1", "protein_name": "PNN interacting serine and arginine rich protein", "gene_name": "PNISR", "tax_id": 9031, "organism": "Gallus gallus", "sequence": { "sequence": "MWDQPWQQWPLNQQQWMQSFQHQQDPSQIDWAALAQAWIAQREASGQQSVVEQQGMMPNGQDISGIESGSNNHNNFQGDPNFNRMWQPEWGMPHQPPHPPPDQQWMAPTTGQMEIVPPSEDSNSQDSGEFASDNRHIFNQNNHNFGAPPDNFAMGPVNQFDYQHGAAFGPPQGGFHPPYWQPGPPGPPGPPAPSAPPQNRRERPSFRDRQRSPIAMPVKQEPPQIDAVKRRTLPAWIREGLEKMEREKQKKLEKERMEQQRSQMSKKEKKENDEAEEGDGPRLPQKSKFDSDEEDEDAENTEAVSVGKISRSPSPVPQEEQSEPEMTEEEKEYQMMMLTKMMLTEILLDVTNEEIYYVAKDVHRKATKAPAKQLAQSSALASLTGLGGLGGYGSGDSEDERSDRGSESSDTDDEELRHRIRQKQEAFWRKEREQQLLLEKQLEEERLQIDKVSKEMNEYMNKEQNSISTSQEAKEIEADMVHDKKRSPNAIALDIEPKKEGKEKERTGRSRSRTSSSGSTSSNSRSSSSSSTVSSSSYSSSSGSSRSSSRSSSPKRKKRHSRSRTPSHKVRRSRSRSYSHRNRRERSRSREKIRERRRSSRNQSAERGERRRIQSPSQERSWDRRRSSSSRDRRVGRASRSRSRDRRKPEEQHRSPPGNRHKHKSDGKEQERKKEHGGTVDKDRKKNRERERDQEKRKDKPKKEEKESKASNHDDNRLKRKRDSERTFPRSETISVKIIRQDSRPDSKKVTTKDSRKQSGSESSARSSSESPGSSKEKKAKKSKHIRSCSMEKSQRSGKKASRKHKSKSRSRSTTPPRRKR", "length": 821 }, "evidence": [ { "id": "F1N5A3", "url": "https://omabrowser.org/oma/group/F1N5A3/", "database": "OMA" } ], "glygen_name": "Chicken", "common_name": "Chicken" }, { "uniprot_canonical_ac": "A2AJT4-1", "protein_name": "Arginine/serine-rich protein PNISR", "gene_name": "Pnisr", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MWDQGGQPWQQWPLNQQQWMQSFQHQQDPSQIDWAALAQAWIAQREASGQQSIVEQPPGMMPNGQDMSAMESGPNNHGNFQGDSNFNRMWQPEWGMHQQPPHPPPEQPWMPPAPGPMDIVPPSEDSNSQDSGEFAPDNRHIFNQNNHNFGGPPDNFAVGPVNQFDYQHGAAFGPPQGGFHPPYWQPGPPGPPAPTQNRRERPPSFRDRQRSPIALPVKQEPPQIDAVKRRTLPAWIREGLEKMEREKQKKLEKERMEQQRSQLSKKEKKATEDAEGGDGPRLPQRSKFDSDEEDEDAENLEAVSSGKVTRSPSPAPQEEHSEPEMTEEEKEYQMMLLTKMLLTEILLDVTDEEIYYVAKDAHRKATKAPAKQLAQSSALASLTGLGGLGGYGSGDSEDERSDRGSESSDTDDEELRHRIRQKQEAFWRKEKEQQLLQDKQIEEEKQQTERVTKEMNEFIHREQNSLSLLEASEADRDAVNDKKRTPNEAPSVLEPKREHKGKEKERGSRSGSSSSGSSSSGSRTSSSSSSVSSSSYSSSSGSSCTSSRSSSPKRRKRPSRSRSPPAKARRSRSRSYSRRVKVDSSRTRGKLRDRRRSNRSSIERERRRNRSPSRDRRRSRSRSRDRRTNRSSRSRSRDRRKIEDPRGNLSGNSHKHKGEAKEQDRKKERSRSVDKDRRKKDKERDRELDKRKEKQKREEKDFKFSSQDDRLKRKRESERTFCRSGSISVKVIRHDSRQDSKKNATKDSKRHSGSDSSGRSSSESPGSSKEKKAKKPKHSRSRSLEKSQRSGKKASRKHKSKSRSR", "length": 805 }, "evidence": [ { "id": "F1N5A3", "url": "https://omabrowser.org/oma/group/F1N5A3/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "F1MAQ8-1", "protein_name": "PNN interacting serine and arginine rich protein", "gene_name": "Pnisr", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MWDQGGQPWQQWPLNQQQWMQSFQHQQDPSQIDWAALAQAWIAQREASGQQSIVEQPPGMMPNGQDMSSMESGPNNHGNFQGDSNFNRMWQPEWGMHQQPPHPPPDQPWMPPTPGPMDIVPPSEDSNSQDSGEFAPDNRHIFNQNNHNFGGPPDNFAVGPVNQFDYQHGAAFGPPQGGFHPPYWQPGPPGPPAPTQNRRERPPSFRDRQRSPIALPVKQEPPQIDAVKRRTLPAWIREGLEKMEREKQKKLEKERMEQQRSQLSHKEKKAAEDAEGGHGPRLPQRSKFDSDDEDEDAENLEAVSSGKVTRSPSPAPQEEHSEPEMTEEEKEYQMMLLTKMLLTEILLDVTDEEIYYVAKDAHRKATKAPAKQLAQSSALASLTGLGGLGGYGSGDSEDERSDRGSESSDTDDEELRHRIRQKQEAFWRKEKEQQLLQDKQMEEEKQQTERVTKEMNEFIHREQNSLSLLEASEADGDTVNEKKRTPNEAPSVLEPKREHKGKEKERRSRSGSSSSGSSSSNSRSSSSSSSVSSSSYSSSSGSSCTSSRSSSPKRKKRHSRSRSPTVKARRSRSRSYSRRIKIDSSRTRVKLRDRRRSNRSSIERERRRNRSPSRDRRRSRSRSRDRRTNRSSRSRSRDRRKIEDPRGNLSGNSHKHKGEAKEQDRKKERSRSVDKDRRKKDKERDREQDKRKEKQKREEKDFKFSSQDDRLKRKRESERTFCRSGSISVKVIRHDSRQDSKKNATKDSKKHSGSDSSGRSSSESPGSSKEKKAKKPKHSRSRSMEKSQRSGKKASRKHKSKSRSRSTTPPRRKR", "length": 814 }, "evidence": [ { "id": "F1N5A3", "url": "https://omabrowser.org/oma/group/F1N5A3/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "Q86B99-1", "protein_name": "Arginine/serine-rich protein PNISR", "gene_name": "CG18546", "tax_id": 7227, "organism": "Drosophila melanogaster", "sequence": { "sequence": "MFPGGNGNADLGYNKHAHVHGLGQHGHGHNHNHNQFLAQPPPPPTHFSLPSGGGQGMVTPMVAAGLPLAMQGGVGIDWAQLAQQWIHMRDATPVPMPLAPPPPIISNLREYHQQTLAMPVPSVVRAGFPQLEEHGEADMDMDDENDRGHSTETPPPPAPLVTQSQWLAGTEVAGQIPDASNGAAVTLGKQPWTGWQMQTDKSGNSTAHIPSLLKLNVSNPNEPHQQLQLQLQAHQQQQQQHAPQPTHPHHPPAHQPHAHPHHLTPHTHLPPQHTQQTHAESGSSGASSEIDANKRKMLPAWIREGLEKMEREKQRQLERQQSSMTTPDVEVNHVKQVSSKTLTTPGNLLNIANVASDSEDSIDVPVEARGELKVQQIGNELISKDDDRSSSSSEEPESELHGAIETGNRTVAEHVRMATVNDVNGKNYEERLADLMLVVRRTLTEILLETTNEEIAAIAGETLKAHRAKASSAQVIRKSALSSITGNLGLAAYGDSSSETEDDEDDEDERQAGAGKDAEKSAQLSAEELKARIRRSKRSFEKVIDDIEDRVAKQELLDEQTLLRHRKRELERSVTGGGEHRRPAANPEPPSESASQATQEKHQQSNGIGDAHKSKELLSIHCHHLGKRLSRKERTTRFSDNKDGKQQSQSFVQQVVATAVVPPPGSLSNSSPQKLKPVPNPATNLLQMPESVATMLTAADKALHKANKSSHKKSKRRHSSPSSSSSSSGSSSSSDSDDSSSTSSGSKTSGSRSKRSSRHGHRSHHSSSRSKYERRDRDRERERARERERDRDRSHRQHRSSQLSGSHHQKQRRHRESSHSGEDAGGSSSYHRSSRQSSSRSHDHGSNRSHDHGSSSSGRKRHRTRSRSKSRSTHHSSSKAYSSTSASHPRKRH", "length": 893 }, "evidence": [ { "id": "F1N5A3", "url": "https://omabrowser.org/oma/group/F1N5A3/", "database": "OMA" } ], "glygen_name": "Fruit fly", "common_name": "Fruit fly" }, { "uniprot_canonical_ac": "Q8TF01-1", "protein_name": "Arginine/serine-rich protein PNISR", "gene_name": "PNISR", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MWDQGGQPWQQWPLNQQQWMQSFQHQQDPSQIDWAALAQAWIAQREASGQQSMVEQPPGMMPNGQDMSTMESGPNNHGNFQGDSNFNRMWQPEWGMHQQPPHPPPDQPWMPPTPGPMDIVPPSEDSNSQDSGEFAPDNRHIFNQNNHNFGGPPDNFAVGPVNQFDYQHGAAFGPPQGGFHPPYWQPGPPGPPAPPQNRRERPSSFRDRQRSPIALPVKQEPPQIDAVKRRTLPAWIREGLEKMEREKQKKLEKERMEQQRSQLSKKEKKATEDAEGGDGPRLPQRSKFDSDEEEEDTENVEAASSGKVTRSPSPVPQEEHSDPEMTEEEKEYQMMLLTKMLLTEILLDVTDEEIYYVAKDAHRKATKAPAKQLAQSSALASLTGLGGLGGYGSGDSEDERSDRGSESSDTDDEELRHRIRQKQEAFWRKEKEQQLLHDKQMEEEKQQTERVTKEMNEFIHKEQNSLSLLEAREADGDVVNEKKRTPNETTSVLEPKKEHKEKEKQGRSRSGSSSSGSSSSNSRTSSTSSTVSSSSYSSSSGSSRTSSRSSSPKRKKRHSRSRSPTIKARRSRSRSYSRRIKIESNRARVKIRDRRRSNRNSIERERRRNRSPSRERRRSRSRSRDRRTNRASRSRSRDRRKIDDQRGNLSGNSHKHKGEAKEQERKKERSRSIDKDRKKKDKEREREQDKRKEKQKREEKDFKFSSQDDRLKRKRESERTFSRSGSISVKIIRHDSRQDSKKSTTKDSKKHSGSDSSGRSSSESPGSSKEKKAKKPKHSRSRSVEKSQRSGKKASRKHKSKSRSR", "length": 805 }, "evidence": [ { "id": "F1N5A3", "url": "https://omabrowser.org/oma/group/F1N5A3/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" } ], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 2, "go_terms": [ { "name": "nuclear speck", "id": "GO:0016607", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016607", "evidence": [ { "database": "UniProtKB", "id": "F1N5A3", "url": "https://www.uniprot.org/uniprotkb/F1N5A3" } ], "pmid": "" }, { "name": "presynaptic active zone", "id": "GO:0048786", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0048786", "evidence": [ { "database": "UniProtKB", "id": "F1N5A3", "url": "https://www.uniprot.org/uniprotkb/F1N5A3" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 487, "end_pos": 489, "annotation": "n_glycosylation_sequon" }, { "start_pos": 609, "end_pos": 611, "annotation": "n_glycosylation_sequon" }, { "start_pos": 629, "end_pos": 631, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [ { "pdb_id": "AF-F1N5A3-F1", "pdb_chain": "global", "start_pos": 1, "end_pos": 814, "overlap": "1.0", "method": "AlphaFold", "type": "alphafold", "resolution": -1.0, "url": "https://data.glygen.org/ln2downloads/pdb/current/AF-F1N5A3-F1.pdb", "url_external": "https://alphafold.ebi.ac.uk/entry/F1N5A3" } ], "lectin_list": [], "domain_list": [], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" }, { "name": "homologset.oma", "label": "OMA Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [ 113 ], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 487, "end_pos": 489 }, { "start_pos": 609, "end_pos": 611 }, { "start_pos": 629, "end_pos": 631 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 1 }, { "field": "total_sites", "count": 1 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 1 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "exact_sites", "count": 1 }, { "field": "exact_o_linked_sites", "count": 1 }, { "field": "fuzzy_sites", "count": 0 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_pos", "start_aa", "end_pos", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 1 }, { "field": "total_sites", "count": 1 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 1 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "exact_sites", "count": 1 }, { "field": "exact_o_linked_sites", "count": 1 }, { "field": "fuzzy_sites", "count": 0 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_pos", "start_aa", "end_pos", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ], "tool_support": { "graph_view": "yes" } }, { "uniprot_canonical_ac": "F6QEG6-1", "uniprot_ac": "F6QEG6", "uniprot_id": "F6QEG6_BOVIN", "mass": { "chemical_mass": 122570.0, "monoisotopic_mass": 122570.0 }, "refseq": {}, "gene_names": [], "protein_names": [ { "name": "Rab GTPase-activating protein 1-like", "type": "recommended", "evidence": [ { "id": "F6QEG6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F6QEG6/entry#names_and_taxonomy" } ] } ], "function": [ { "annotation": "GTP-hydrolysis activating protein (GAP) for small GTPase RAB22A, converting active RAB22A-GTP to the inactive form RAB22A-GDP. Plays a role in endocytosis and intracellular protein transport. Recruited by ANK2 to phosphatidylinositol 3-phosphate (PI3P)-positive early endosomes, where it inactivates RAB22A, and promotes polarized trafficking to the leading edge of the migrating cells. Part of the ANK2/RABGAP1L complex which is required for the polarized recycling of fibronectin receptor ITGA5 ITGB1 to the plasma membrane that enables continuous directional cell migration.", "evidence": [ { "database": "UniProtKB", "id": "A0A3Q1NGF5", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1NGF5#function" }, { "database": "UniProtKB", "id": "ARBA00059592", "url": "https://www.uniprot.org/uniprotkb/ARBA00059592#function" }, { "database": "UniProtKB", "id": "A0AAA9SBS7", "url": "https://www.uniprot.org/uniprotkb/A0AAA9SBS7#function" }, { "database": "UniProtKB", "id": "A0AAA9S8C4", "url": "https://www.uniprot.org/uniprotkb/A0AAA9S8C4#function" }, { "database": "UniProtKB", "id": "A0AAA9TG95", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TG95#function" }, { "database": "UniProtKB", "id": "F6QEG6", "url": "https://www.uniprot.org/uniprotkb/F6QEG6#function" }, { "database": "UniProtKB", "id": "A0AAF6DM07", "url": "https://www.uniprot.org/uniprotkb/A0AAF6DM07#function" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Bos taurus", "taxid": 9913, "evidence": [ { "database": "UniProtKB", "id": "F6QEG6", "url": "https://www.uniprot.org/uniprotkb/F6QEG6" } ], "common_name": "Bovine", "glygen_name": "Bovine", "reference_species": "Bos taurus [9913]" } ], "gene": [ { "name": "", "url": "https://www.uniprot.org/uniprotkb/F6QEG6", "locus": {} } ], "crossref": [ { "id": "F6QEG6", "url": "https://alphafold.ebi.ac.uk/entry/F6QEG6", "database": "AlphaFoldDB", "categories": [] }, { "id": "ENSBTAG00000049490", "url": "https://bgee.org/?page=gene&gene_id=ENSBTAG00000049490", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "cd01211", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd01211", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "IPR000195", "url": "https://www.ebi.ac.uk/interpro/entry/IPR000195", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR006020", "url": "https://www.ebi.ac.uk/interpro/entry/IPR006020", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR011993", "url": "https://www.ebi.ac.uk/interpro/entry/IPR011993", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR022164", "url": "https://www.ebi.ac.uk/interpro/entry/IPR022164", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR035969", "url": "https://www.ebi.ac.uk/interpro/entry/IPR035969", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR050302", "url": "https://www.ebi.ac.uk/interpro/entry/IPR050302", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "PTHR47219", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR47219", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR47219:SF7", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR47219:SF7", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR47728", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR47728", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR47728:SF1", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR47728:SF1", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00566", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00566", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF00640", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00640", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF12473", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF12473", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "A0A3Q1NGF5", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1NGF5", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A3Q1NGF5-1", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1NGF5-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0AAA9S8C4", "url": "https://www.uniprot.org/uniprotkb/A0AAA9S8C4", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0AAA9S8C4-1", "url": "https://www.uniprot.org/uniprotkb/A0AAA9S8C4-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0AAA9SBS7", "url": "https://www.uniprot.org/uniprotkb/A0AAA9SBS7", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0AAA9SBS7-1", "url": "https://www.uniprot.org/uniprotkb/A0AAA9SBS7-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0AAA9T3X6", "url": "https://www.uniprot.org/uniprotkb/A0AAA9T3X6", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0AAA9T3X6-1", "url": "https://www.uniprot.org/uniprotkb/A0AAA9T3X6-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0AAA9T428", "url": "https://www.uniprot.org/uniprotkb/A0AAA9T428", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0AAA9T428-1", "url": "https://www.uniprot.org/uniprotkb/A0AAA9T428-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0AAA9TG95", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TG95", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0AAA9TG95-1", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TG95-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0AAA9U1W2", "url": "https://www.uniprot.org/uniprotkb/A0AAA9U1W2", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0AAA9U1W2-1", "url": "https://www.uniprot.org/uniprotkb/A0AAA9U1W2-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0AAF6DM07", "url": "https://www.uniprot.org/uniprotkb/A0AAF6DM07", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0AAF6DM07-1", "url": "https://www.uniprot.org/uniprotkb/A0AAF6DM07-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "F6QEG6", "url": "https://www.uniprot.org/uniprotkb/F6QEG6", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "F6QEG6-1", "url": "https://www.uniprot.org/uniprotkb/F6QEG6-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MNREAWSAAVHGVGKSWVDVEREVCRTEMEVRASLQKVSGSSDSVTTLNSEEFVLVPQHGGDTSTKDDEKPELKIVSNGDEQLEKAMEEILRDSEKGQSSLPVDCPSSSEISDHSFGNISARQTNKPSLQLILDPSNTEISTPRPSSLSEIPEEDSVLFNKLTYLGCMKVSSPRNEVEALRAMATMKSASQHPFPVTLYVPNVPEGSVRIIDQSNNMEIASFPIYKVLFCARGHDGTTESNCFAFTESSHGSEEFQIHVFSCEIKEAVSRILYSFCTAFKRSSRQVSDVKDSVIPTPDSDVFTFSVSLEVKEDDGKGNFSPVPKDRDKFYFKLKQGIEKKLVITVQQLSNKELAIERCFGMLLSPGRNVKNSDMHLLDMESMGKSCDGRAYVITGMWNPNAPIFLALNEETPKDKRVYMTVAVDMVVTEVVEPVRFLLETVVRVYPANERFWYFSRKTFTETFFMRLKQSEGKGHTNAGDAIYEVVSLQRESEKEDPVTPTSGGGPLSPQEDEAEEESDNELSSGTGDVSKDCPEKILYSWGELLGRWHSNLGARPKGLSTLVKSGVPEALRAEVWQLLAGCHDNQAMLDRYRLLITKDSAQESVITRDIHRTFPAHDYFKDTGGDGQESLYKICKAYSVYDEDIGYCQGQSFLAAVLLLHMPEEQAFCVLVKIMYDYGLRDLYKNNFEDLHCKFYQLERLMQEQLPDLHNHFSDLNLEAHMYASQWFLTLFTAKFPLCMVFHIIDLLLSEGLNIIFHVALALLKTSKEDLLQADFEGALKFFRVQLPKRYRAEENARRLMEQACNIKVPTKKLKKYEKEYQTMRESQLQQEDPMDRYKRENRRLQEASMRLEQENDDLAHELVTSKIALRNDLDQAEDKADVLNKELLLTKQRLVETEEEKRKQEEETAQLKEVFRKQLEKAEYEIKKTTAIIAEYKQICSQLSTRLEKQQAASKEELEVVKGKMMACKHCSDIFSKEGALKAAAVSREDQGIESDDEKDSLKKQLREMELELAQTKLQLVEAKCKIQELEHQRGALMNEIQAAKNSWFSKTLNSIKTATGTQPLQPPQATQPPKEST", "length": 1079, "header": "tr|F6QEG6-1|F6QEG6_BOVIN Isoform 1 of Rab GTPase-activating protein 1-like OS=Bos taurus OX=9913 GN= PE=4 SV=1 CANONICAL=F6QEG6-1" }, "isoforms": [ { "isoform_ac": "A0A3Q1NGF5-1", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1NGF5/entry", "sequence": { "sequence": "MEVRASLQKVSGSSDSVTTLNSEEFVLVPQHGGDTSTKDDEKPELKIVSNGDEQLEKAMEEILRDSEKGQSSLPVDCPSSSEISDHSFGNISARQTNKPSLQLILDPSNTEISTPRPSSLSEIPEEDSVLFNKLTYLGCMKVSSPRNEVEALRAMATMKSASQHPFPVTLYVPNVPEGSVRIIDQSNNMEIASFPIYKVLFCARGHDGTTESNCFAFTESSHGSEEFQIHVFSCEIKEAVSRILYSFCTAFKRSSRQVSDVKDSVIPTPDSDVFTFSVSLEVKEDDGKGNFSPVPKDRDKFYFKLKQGIEKKLVITVQQLSNKELAIERCFGMLLSPGRNVKNSDMHLLDMESMGKSCDGRAYVITGMWNPNAPIFLALNEETPKDKRVYMTVAVDMVVTEVVEPVRFLLETVVRVYPANERFWYFSRKTFTETFFMRLKQSEGKGHTNAGDAIYEVVSLQRESEKEDPVTPTSGGGPLSPQEDEAEEESDNELSSGTGDVSKDCPEKILYSWGELLGRWHSNLGARPKGLSTLVKSGVPEALRAEVWQLLAGCHDNQAMLDRYRLLITKDSAQESVITRDIHRTFPAHDYFKDTGGDGQESLYKICKAYSVYDEDIGYCQGQSFLAAVLLLHMPEEQAFCVLVKIMYDYGLRDLYKNNFEDLHCKFYQLERLMQEQLPDLHNHFSDLNLEAHMYASQWFLTLFTAKFPLCMVFHIIDLLLSEGLNIIFHVALALLKTSKEDLLQADFEGALKFFRVQLPKRYRAEENARRLMEQACNIKLELHFPASCAIACSHLGRGWASWAEE", "length": 806, "header": "tr|A0A3Q1NGF5-1|F6QEG6_BOVIN Computationally mapped isoform of Rab GTPase-activating protein 1-like OS=Bos taurus OX=9913 GN= PE=4 SV=2 CANONICAL=F6QEG6-1" }, "locus": { "chromosome": "16", "start_pos": 56092645, "end_pos": 55555595, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000073026.3", "url": "https://www.ensembl.org/id/ENSBTAT00000073026.3" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000070886.2", "url": "https://www.ensembl.org/id/ENSBTAP00000070886.2" } ] } }, { "isoform_ac": "A0AAA9S8C4-1", "url": "https://www.uniprot.org/uniprotkb/A0AAA9S8C4/entry", "sequence": { "sequence": "MEVRASLQKVSGSSDSVTTLNSEEFVLVPQHGGDTSTKDDEKPELKIVSNGDEQLEKAMEEILRDSEKGQSSLPVDCPSSSEISDHSFGNISARQTNKPSLQLILDPSNTEISTPRPSSLSEIPEEDSVLFNKLTYLGCMKVSSPRNEVEALRAMATMKSASQHPFPVTLYVPNVPEGSVRIIDQSNNMEIASFPIYKVLFCARGHDGTTESNCFAFTESSHGSEEFQIHVFSCEIKEAVSRILYSFCTAFKRSSRQVSDVKDSVIPTPDSDVFTFSVSLEVKEDDGKGNFSPVPKDRDKFYFKLKQGIEKKLVITVQQLSNKELAIERCFGMLLSPGRNVKNSDMHLLDMESMGKSCDGRAYVITGMWNPNAPIFLALNEETPKDKRVYMTVAVDMVVTEVVEPVRFLLETVVRVYPANERFWYFSRKTFTETFFMRLKQSEGKGHTNAGDAIYEVVSLQRESEKEDPVTPTSGGGPLSPQEDEAEEESDNELSSGTGDVSKDCPEKILYSWGELLGRWHSNLGARPKGLSTLVKSGVPEALRAEVWQLLAGCHDNQAMLDRYRLLITKDSAQESVITRDIHRTFPAHDYFKDTGGDGQESLYKICKAYSVYDEDIGYCQGQSFLAAVLLLHMPEEQAFCVLVKIMYDYGLRDLYKNNFEDLHCKFYQLERLMQEQLPDLHNHFSDLNLEAHMYASQWFLTLFTAKFPLCMVFHIIDLLLSEGLNIIFHVALALLKTSKEDLLQADFEGALKFFRVQLPKRYRAEENARRLMEQACNIKRENRRLQEASMRLEQENDDLAHELVTSKIALRNDLDQAEDKADVLNKELLLTKQRLVETEEEKRKQEEETAQLKEVFRKQLEKAEYEIKKTTAIIAEYKQICSQLSTRLEKQQAASKEELEVVKGKMMACKHCSDIFSKEGALKAAAVSREDQGIESDDEKDSLKKQLREMELELAQTKLQLVEAKCKIQELEHQRGALMNEIQAAKNSWFSKTLNSIKTATGTQPLQPPQATQPPKEST", "length": 1020, "header": "tr|A0AAA9S8C4-1|F6QEG6_BOVIN Computationally mapped isoform of Rab GTPase-activating protein 1-like OS=Bos taurus OX=9913 GN= PE=4 SV=2 CANONICAL=F6QEG6-1" }, "locus": { "chromosome": "16", "start_pos": 56219098, "end_pos": 55555595, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000126214.2", "url": "https://www.ensembl.org/id/ENSBTAT00000126214.2" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000081500.2", "url": "https://www.ensembl.org/id/ENSBTAP00000081500.2" } ] } }, { "isoform_ac": "A0AAA9SBS7-1", "url": "https://www.uniprot.org/uniprotkb/A0AAA9SBS7/entry", "sequence": { "sequence": "MEVRASLQKVSGSSDSVTTLNSEEFVLVPQHGGDTSTKDDEKPELKIVSNGDEQLEKAMEEILRDSEKGQSSLPVDCPSSSEISDHSFGNISARQTNKPSLQLILDPSNTEISTPRPSSLSEIPEEDSVLFNKLTYLGCMKVSSPRNEVEALRAMATMKSASQHPFPVTLYVPNVPEGSVRIIDQSNNMEIASFPIYKVLFCARGHDGTTESNCFAFTESSHGSEEFQIHVFSCEIKEAVSRILYSFCTAFKRSSRQVSDVKDSVIPTPDSDVFTFSVSLEVKEDDGKGNFSPVPKDRDKFYFKLKQGIEKKLVITVQQLSNKELAIERCFGMLLSPGRNVKNSDMHLLDMESMGKSCDGRAYVITGMWNPNAPIFLALNEETPKDKRVYMTVAVDMVVTEVVEPVRFLLETVVRVYPANERFWYFSRKTFTETFFMRLKQSEGKGHTNAGDAIYEVVSLQRESEKEDPVTPTSGGGPLSPQEDEAEEESDNELSSGTGDVSKDCPEKILYSWGELLGRWHSNLGARPKGLSTLVKSGVPEALRAEVWQLLAGCHDNQAMLDRYRLLITKDSAQESVITRDIHRTFPAHDYFKDTGGDGQESLYKICKAYSVYDEDIGYCQGQSFLAAVLLLHMPEEQAFCVLVKIMYDYGLRDLYKNNFEDLHCKFYQLERLMQEQLPDLHNHFSDLNLEAHMYASQWFLTLFTAKFPLCMVFHIIDLLLSEGLNIIFHVALALLKTSKEDLLQADFEGALKFFRVQLPKRYRAEENARRLMEQACNIKVPTKKLKKYEKEYQTMRESQLQQEDPMDRYKFVYL", "length": 815, "header": "tr|A0AAA9SBS7-1|F6QEG6_BOVIN Computationally mapped isoform of Rab GTPase-activating protein 1-like OS=Bos taurus OX=9913 GN= PE=4 SV=2 CANONICAL=F6QEG6-1" }, "locus": { "chromosome": "16", "start_pos": 56189172, "end_pos": 55555595, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000105418.2", "url": "https://www.ensembl.org/id/ENSBTAT00000105418.2" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000080947.2", "url": "https://www.ensembl.org/id/ENSBTAP00000080947.2" } ] } }, { "isoform_ac": "A0AAA9T3X6-1", "url": "https://www.uniprot.org/uniprotkb/A0AAA9T3X6/entry", "sequence": { "sequence": "MEVRASLQKVSGSSDSVTTLNSEEFVLVPQHGGDTSTKDDEKPELKIVSNGDEQLEKAMEEILRDSEKGQSSLPVDCPSSSEISDHSFGNISARQTNKPSLQLILDPSNTEISTPRPSSLSEIPEEDSVLFNKLTYLGCMKVSSPRNEVEALRAMATMKSASQHPFPVTLYVPNVPEGSVRIIDQSNNMEIASFPIYKVLFCARGHDGTTESNCFAFTESSHGSEEFQIHVFSCEIKEAVSRILYSFCTAFKRSSRQVSDVKDSVIPTPDSDVFTFSVSLEVKEDDGKGNFSPVPKDRDKFYFKLKQGIEKKLVITVQQLSNKELAIERCFGMLLSPGRNVKNSDMHLLDMESMGKSCDGRAYVITGMWNPNAPIFLALNEETPKDKRVYMTVAVDMVVTEVVEPVRFLLETVVRVYPANERFWYFSRKTFTETFFMRLKQSEGKGHTNAGDAIYEVVSLQRESEKEDPVTPTSGGGPLSPQEDEAEEESDNELSSGTGDVSKDCPEKILYSWGELLGRWHSNLGARPKGLSTLVKSGVPEALRAEVWQLLAGCHDNQAMLDRYRLLITKDSAQESVITRDIHRTFPAHDYFKDTGGDGQESLYKICKAYSVYDEDIGYCQGQSFLAAVLLLHMPEEQAFCVLVKIMYDYGLRDLYKNNFEDLHCKFYQLERLMQEQLPDLHNHFSDLNLEAHMYASQWFLTLFTAKFPLCMVFHIIDLLLSEGLNIIFHVALALLKKQPAPAAAAAKSLQSCPTLFDPIDGSPPGSPIPGILQTSKEDLLQADFEGALKFFRVQLPKRYRAEENARRLMEQACNIKVPTKKLKKYEKEYQTMRESQLQQEDPMDRYKFVYL", "length": 852, "header": "tr|A0AAA9T3X6-1|F6QEG6_BOVIN Computationally mapped isoform of Rab GTPase-activating protein 1-like OS=Bos taurus OX=9913 GN= PE=4 SV=1 CANONICAL=F6QEG6-1" }, "locus": { "chromosome": "16", "start_pos": 56189172, "end_pos": 55555595, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000116985.2", "url": "https://www.ensembl.org/id/ENSBTAT00000116985.2" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000093504.1", "url": "https://www.ensembl.org/id/ENSBTAP00000093504.1" } ] } }, { "isoform_ac": "A0AAA9T428-1", "url": "https://www.uniprot.org/uniprotkb/A0AAA9T428/entry", "sequence": { "sequence": "MEVRASLQKVSGSSDSVTTLNSEEFVLVPQHGGDTSTKDDEKPELKIVSNGDEQLEKAMEEILRDSEKGQSSLPVDCPSSSEISDHSFGNISARQTNKPSLQLILDPSNTEISTPRPSSLSEIPEEDSVLFNKLTYLGCMKVSSPRNEVEALRAMATMKSASQHPFPVTLYVPNVPEGSVRIIDQSNNMEIASFPIYKVLFCARGHDGTTESNCFAFTESSHGSEEFQIHVFSCEIKEAVSRILYSFCTAFKRSSRQVSDVKDSVIPTPDSDVFTFSVSLEVKEDDGKGNFSPVPKDRDKFYFKLKQGIEKKLVITVQQLSNKELAIERCFGMLLSPGRNVKNSDMHLLDMESMGKSCDGRAYVITGMWNPNAPIFLALNEETPKDKRVYMTVAVDMVVTEVVEPVRFLLETVVRVYPANERFWYFSRKTFTETFFMRLKQSEGKGHTNAGDAIYEVVSLQRESEKEDPVTPTSGGGPLSPQEDEAEEESDNELSSGTGDVSKDCPEKILYSWGELLGRWHSNLGARPKGLSTLVKSGVPEALRAEVWQLLAGCHDNQAMLDRYRLLITKDSAQESVITRDIHRTFPAHDYFKDTGGDGQESLYKICKAYSVYDEDIGYCQGQSFLAAVLLLHMPEEQAFCVLVKIMYDYGLRDLYKNNFEDLHCKFYQLERLMQEQLPDLHNHFSDLNLEAHMYASQWFLTLFTAKFPLCMVFHIIDLLLSESIYSTCLKKISLIYLLGMQITTMGCCHSVHGGKRKMVWVFPL", "length": 765, "header": "tr|A0AAA9T428-1|F6QEG6_BOVIN Computationally mapped isoform of Rab GTPase-activating protein 1-like OS=Bos taurus OX=9913 GN= PE=4 SV=1 CANONICAL=F6QEG6-1" }, "locus": { "chromosome": "16", "start_pos": 55963109, "end_pos": 55555595, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000090386.2", "url": "https://www.ensembl.org/id/ENSBTAT00000090386.2" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000091258.1", "url": "https://www.ensembl.org/id/ENSBTAP00000091258.1" } ] } }, { "isoform_ac": "A0AAA9TG95-1", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TG95/entry", "sequence": { "sequence": "MEVRASLQKVSGSSDSVTTLNSEEFVLVPQHGGDTSTKDDEKPELKIVSNGDEQLEKAMEEILRDSEKGQSSLPVDCPSSSEISDHSFGNISARQTNKPSLQLILDPSNTEISTPRPSSLSEIPEEDSVLFNKLTYLGCMKVSSPRNEVEALRAMATMKSASQHPFPVTLYVPNVPEGSVRIIDQSNNMEIASFPIYKVLFCARGHDGTTESNCFAFTESSHGSEEFQIHVFSCEIKEAVSRILYSFCTAFKRSSRQVSDVKDSVIPTPDSDVFTFSVSLEVKEDDGKGNFSPVPKDRDKFYFKLKQGIEKKLVITVQQLSNKELAIERCFGMLLSPGRNVKNSDMHLLDMESMGKSCDGRAYVITGMWNPNAPIFLALNEETPKDKRVYMTVAVDMVVTEVVEPVRFLLETVVRVYPANERFWYFSRKTFTETFFMRLKQSEGKGHTNAGDAIYEVVSLQRESEKEDPVTPTSGGGPLSPQEDEAEEESDNELSSGTGDVSKDCPEKILYSWGELLGRWHSNLGARPKGLSTLVKSGVPEALRAEVWQLLAGCHDNQAMLDRYRLLITKDSAQESVITRDIHRTFPAHDYFKDTGGDGQESLYKICKAYSVYDEDIGYCQGQSFLAAVLLLHMPEEQAFCVLVKIMYDYGLRDLYKNNFEDLHCKFYQLERLMQEQLPDLHNHFSDLNLEAHMYASQWFLTLFTAKFPLCMVFHIIDLLLSEGLNIIFHVALALLKTSKEDLLQADFEGALKFFRVQLPKRYRAEENARRLMEQACNIKVPTKKLKKYEKEYQTMRESQLQQEDPMDRYKRENRRLQEASMRLEQENDDLAHELVTSKIALRNDLDQAEDKADVLNKELLLTKQRLVETEEEKRKQEEETAQLKEVFRKQLEKAEYEIKKTTAIIAEYKQICSQLSTRLEKQQAASKEELEVVKELEHQRGALMNEIQAAKNSWFSKTLNSIKTATGTQPLQPPQATQPPKEST", "length": 985, "header": "tr|A0AAA9TG95-1|F6QEG6_BOVIN Computationally mapped isoform of Rab GTPase-activating protein 1-like OS=Bos taurus OX=9913 GN= PE=4 SV=1 CANONICAL=F6QEG6-1" }, "locus": { "chromosome": "16", "start_pos": 56219098, "end_pos": 55555595, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000123226.2", "url": "https://www.ensembl.org/id/ENSBTAT00000123226.2" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000096058.1", "url": "https://www.ensembl.org/id/ENSBTAP00000096058.1" } ] } }, { "isoform_ac": "A0AAA9U1W2-1", "url": "https://www.uniprot.org/uniprotkb/A0AAA9U1W2/entry", "sequence": { "sequence": "MEVRASLQKVSGSSDSVTTLNSEEFVLVPQHGGDTSTKDDEKPELKIVSNGDEQLEKAMEEILRDSEKGQSSLPVDCPSSSEISDHSFGNISARQTNKPSLQLILDPSNTEISTPRPSSLSEIPEEDSVLFNKLTYLGCMKVSSPRNEVEALRAMATMKSASQHPFPVTLYVPNVPEGSVRIIDQSNNMEIASFPIYKVLFCARGHDGTTESNCFAFTESSHGSEEFQIHVFSCEIKEAVSRILYSFCTAFKRSSRQVSDVKDSVIPTPDSDVFTFSVSLEVKEDDGKGNFSPVPKDRDKFYFKLKQGIEKKLVITVQQLSNKELAIERCFGMLLSPGRNVKNSDMHLLDMESMGKSCDGRAYVITGMWNPNAPIFLALNEETPKDKRVYMTVAVDMVVTEVVEPVRFLLETVVRVYPANERFWYFSRKTFTETFFMRLKQSEGKGHTNAGDAIYEVVSLQRESEKEDPVTPTSGGGPLSPQEDEAEEESDNELSSGTGDVSKDCPEKILYSWGELLGRWHSNLGARPKGLSTLVKSGVPEALRAEVWQLLAGCHDNQAMLDRYRLLITKDSAQESVITRDIHRTFPAHDYFKDTGGDGQESLYKICKAYSVYDEDIGYCQGQSFLAAVLLLHMPEEQAFCVLVKIMYDYGLRDLYKNNFEDLHCKFYQLERLMQEQLPDLHNHFSDLNLEAHMYASQWFLTLFTAKFPLCMVFHIIDLLLSEGLNIIFHVALALLKVPTKKLKKYEKEYQTMRESQLQQEDPMDRYKRENRRLQEASMRLEQENDDLAHELVTSKIALRNDLDQAEDKADVLNKELLLTKQRLVETEEEKRKQEEETAQLKEVFRKQLEKAEYEIKKTTAIIAEYKQICSQLSTRLEKQQAASKEELEVVKGKMMACKHCSDIFSKEGALKAAAVSREDQGIESDDEKDSLKKQLREMELELAQTKLQLVEAKCKIQELEHQRGALMNEIQAAKNSWFSKTLNSIKTATGTQPLQPPQATQPPKEST", "length": 1008, "header": "tr|A0AAA9U1W2-1|A0AAA9U1W2_BOVIN Computationally mapped isoform of RAB GTPase activating protein 1 like OS=Bos taurus OX=9913 GN= PE=4 SV=1 CANONICAL=F6QEG6-1" }, "locus": { "chromosome": "16", "start_pos": 56219098, "end_pos": 55555595, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000123171.2", "url": "https://www.ensembl.org/id/ENSBTAT00000123171.2" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000103882.1", "url": "https://www.ensembl.org/id/ENSBTAP00000103882.1" } ] } }, { "isoform_ac": "A0AAF6DM07-1", "url": "https://www.uniprot.org/uniprotkb/A0AAF6DM07/entry", "sequence": { "sequence": "MEVRASLQKVSGSSDSVTTLNSEEFVLVPQHGGDTSTKDDEKPELKIVSNGDEQLEKAMEEILRDSEKGQSSLPVDCPSSSEISDHSFGNISARQTNKPSLQLILDPSNTEISTPRPSSLSEIPEEDSVLFNKLTYLGCMKVSSPRNEVEALRAMATMKSASQHPFPVTLYVPNVPEGSVRIIDQSNNMEIASFPIYKVLFCARGHDGTTESNCFAFTESSHGSEEFQIHVFSCEIKEAVSRILYSFCTAFKRSSRQVSDVKDSVIPTPDSDVFTFSVSLEVKEDDGKGNFSPVPKDRDKFYFKLKQGIEKKLVITVQQLSNKELAIERCFGMLLSPGRNVKNSDMHLLDMESMGKSCDGRAYVITGMWNPNAPIFLALNEETPKDKRVYMTVAVDMVVTEVVEPVRFLLETVVRVYPANERFWYFSRKTFTETFFMRLKQSEGKGHTNAGDAIYEVVSLQRESEKEDPVTPTSGGGPLSPQEDEAEEESDNELSSGTGDVSKDCPEKILYSWGELLGRWHSNLGARPKGLSTLVKSGVPEALRAEVWQLLAGCHDNQAMLDRYRLLITKDSAQESVITRDIHRTFPAHDYFKDTGGDGQESLYKICKAYSVYDEDIGYCQGQSFLAAVLLLHMPEEQAFCVLVKIMYDYGLRDLYKNNFEDLHCKFYQLERLMQEQLPDLHNHFSDLNLEAHMYASQWFLTLFTAKFPLCMVFHIIDLLLSEGLNIIFHVALALLKTSKEDLLQADFEGALKFFRVQLPKRYRAEENARRLMEQACNIKPSGL", "length": 784, "header": "tr|A0AAF6DM07-1|A0AAF6DM07_BOVIN Computationally mapped isoform of Rab GTPase-activating protein 1-like OS=Bos taurus OX=9913 GN= PE=4 SV=1 CANONICAL=F6QEG6-1" }, "locus": { "chromosome": "16", "start_pos": 56076225, "end_pos": 55555595, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000019777.8", "url": "https://www.ensembl.org/id/ENSBTAT00000019777.8" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000019777.6", "url": "https://www.ensembl.org/id/ENSBTAP00000019777.6" } ] } }, { "isoform_ac": "F6QEG6-1", "url": "https://www.uniprot.org/uniprotkb/F6QEG6/entry", "sequence": { "sequence": "MNREAWSAAVHGVGKSWVDVEREVCRTEMEVRASLQKVSGSSDSVTTLNSEEFVLVPQHGGDTSTKDDEKPELKIVSNGDEQLEKAMEEILRDSEKGQSSLPVDCPSSSEISDHSFGNISARQTNKPSLQLILDPSNTEISTPRPSSLSEIPEEDSVLFNKLTYLGCMKVSSPRNEVEALRAMATMKSASQHPFPVTLYVPNVPEGSVRIIDQSNNMEIASFPIYKVLFCARGHDGTTESNCFAFTESSHGSEEFQIHVFSCEIKEAVSRILYSFCTAFKRSSRQVSDVKDSVIPTPDSDVFTFSVSLEVKEDDGKGNFSPVPKDRDKFYFKLKQGIEKKLVITVQQLSNKELAIERCFGMLLSPGRNVKNSDMHLLDMESMGKSCDGRAYVITGMWNPNAPIFLALNEETPKDKRVYMTVAVDMVVTEVVEPVRFLLETVVRVYPANERFWYFSRKTFTETFFMRLKQSEGKGHTNAGDAIYEVVSLQRESEKEDPVTPTSGGGPLSPQEDEAEEESDNELSSGTGDVSKDCPEKILYSWGELLGRWHSNLGARPKGLSTLVKSGVPEALRAEVWQLLAGCHDNQAMLDRYRLLITKDSAQESVITRDIHRTFPAHDYFKDTGGDGQESLYKICKAYSVYDEDIGYCQGQSFLAAVLLLHMPEEQAFCVLVKIMYDYGLRDLYKNNFEDLHCKFYQLERLMQEQLPDLHNHFSDLNLEAHMYASQWFLTLFTAKFPLCMVFHIIDLLLSEGLNIIFHVALALLKTSKEDLLQADFEGALKFFRVQLPKRYRAEENARRLMEQACNIKVPTKKLKKYEKEYQTMRESQLQQEDPMDRYKRENRRLQEASMRLEQENDDLAHELVTSKIALRNDLDQAEDKADVLNKELLLTKQRLVETEEEKRKQEEETAQLKEVFRKQLEKAEYEIKKTTAIIAEYKQICSQLSTRLEKQQAASKEELEVVKGKMMACKHCSDIFSKEGALKAAAVSREDQGIESDDEKDSLKKQLREMELELAQTKLQLVEAKCKIQELEHQRGALMNEIQAAKNSWFSKTLNSIKTATGTQPLQPPQATQPPKEST", "length": 1079, "header": "tr|F6QEG6-1|F6QEG6_BOVIN Isoform 1 of Rab GTPase-activating protein 1-like OS=Bos taurus OX=9913 GN= PE=4 SV=1 CANONICAL=F6QEG6-1" }, "locus": { "chromosome": "16", "start_pos": 56219098, "end_pos": 55554067, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000033990.7", "url": "https://www.ensembl.org/id/ENSBTAT00000033990.7" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000033892.5", "url": "https://www.ensembl.org/id/ENSBTAP00000033892.5" } ] } } ], "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "other", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 501, "start_aa": "Thr", "end_pos": 501, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr501", "evidence": [ { "id": "", "database": "GlyGen", "url": "https://data.glygen.org/" } ], "filter_code": "000000000000000010000.00000000001000.0.01000" } ], "phosphorylation": [], "glycation": [], "keywords": [ "glycoprotein", "glycoprotein_predicted" ], "publication": [], "pathway": [], "orthologs": [], "go_annotation": { "categories": [ { "name": "Molecular Function", "total": 2, "go_terms": [ { "name": "GTPase activator activity", "id": "GO:0005096", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005096", "evidence": [ { "database": "UniProtKB", "id": "F6QEG6", "url": "https://www.uniprot.org/uniprotkb/F6QEG6" } ], "pmid": "" }, { "name": "small GTPase binding", "id": "GO:0031267", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0031267", "evidence": [ { "database": "UniProtKB", "id": "F6QEG6", "url": "https://www.uniprot.org/uniprotkb/F6QEG6" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 2, "go_terms": [ { "name": "early endosome", "id": "GO:0005769", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005769", "evidence": [ { "database": "UniProtKB", "id": "F6QEG6", "url": "https://www.uniprot.org/uniprotkb/F6QEG6" } ], "pmid": "" }, { "name": "Golgi apparatus", "id": "GO:0005794", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005794", "evidence": [ { "database": "UniProtKB", "id": "F6QEG6", "url": "https://www.uniprot.org/uniprotkb/F6QEG6" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 2, "go_terms": [ { "name": "endocytosis", "id": "GO:0006897", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006897", "evidence": [ { "database": "UniProtKB", "id": "F6QEG6", "url": "https://www.uniprot.org/uniprotkb/F6QEG6" } ], "pmid": "" }, { "name": "protein transport", "id": "GO:0015031", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0015031", "evidence": [ { "database": "UniProtKB", "id": "F6QEG6", "url": "https://www.uniprot.org/uniprotkb/F6QEG6" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 118, "end_pos": 120, "annotation": "n_glycosylation_sequon" }, { "start_pos": 318, "end_pos": 320, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "F6QEG6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F6QEG6" }, { "id": "PS01179", "database": "PROSITE", "url": "https://prosite.expasy.org/PS01179" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "PID", "eco_id": "ECO_0000259", "start_pos": 164, "end_pos": 279, "start_aa": "Tyr", "end_aa": "Phe", "glycosite_overlap": [] }, { "evidence": [ { "id": "F6QEG6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F6QEG6" }, { "id": "PS50086", "database": "PROSITE", "url": "https://prosite.expasy.org/PS50086" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "Rab-GAP TBC", "eco_id": "ECO_0000259", "start_pos": 566, "end_pos": 752, "start_aa": "Gly", "end_aa": "Gly", "glycosite_overlap": [] } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [ 501 ], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 118, "end_pos": 120 }, { "start_pos": 318, "end_pos": 320 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 1 }, { "field": "total_sites", "count": 1 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 1 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "exact_sites", "count": 1 }, { "field": "exact_o_linked_sites", "count": 1 }, { "field": "fuzzy_sites", "count": 0 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_pos", "start_aa", "end_pos", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 1 }, { "field": "total_sites", "count": 1 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 1 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "exact_sites", "count": 1 }, { "field": "exact_o_linked_sites", "count": 1 }, { "field": "fuzzy_sites", "count": 0 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_pos", "start_aa", "end_pos", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ], "tool_support": { "graph_view": "yes" } }, { "uniprot_canonical_ac": "F1N665-1", "uniprot_ac": "F1N665", "uniprot_id": "F1N665_BOVIN", "mass": { "chemical_mass": 56586.0, "monoisotopic_mass": 56586.0 }, "refseq": {}, "gene_names": [ { "name": "ARSG", "type": "recommended", "evidence": [ { "id": "F1N665", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1N665" } ] } ], "protein_names": [ { "name": "Arylsulfatase G", "type": "recommended", "evidence": [ { "id": "F1N665", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1N665/entry#names_and_taxonomy" } ] }, { "name": "3.1.6.15", "type": "synonym", "evidence": [ { "id": "F1N665", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1N665/entry#names_and_taxonomy" } ] }, { "name": "3.1.6.1", "type": "synonym", "evidence": [ { "id": "F1N665", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1N665/entry#names_and_taxonomy" } ] }, { "name": "N-sulfoglucosamine-3-sulfatase", "type": "synonym", "evidence": [ { "id": "F1N665", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1N665/entry#names_and_taxonomy" } ] } ], "function": [], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Bos taurus", "taxid": 9913, "evidence": [ { "database": "UniProtKB", "id": "F1N665", "url": "https://www.uniprot.org/uniprotkb/F1N665" } ], "common_name": "Bovine", "glygen_name": "Bovine", "reference_species": "Bos taurus [9913]" } ], "gene": [ { "name": "ARSG", "url": "https://www.uniprot.org/uniprotkb/F1N665", "locus": { "chromosome": "19", "start_pos": 61782691, "end_pos": 61886373, "strand": "+", "evidence": [ { "database": "Ensembl Gene", "id": "ENSBTAG00000010637", "url": "https://www.ensembl.org/id/ENSBTAG00000010637" } ] } } ], "crossref": [ { "id": "F1N665", "url": "https://alphafold.ebi.ac.uk/entry/F1N665", "database": "AlphaFoldDB", "categories": [] }, { "id": "ENSBTAG00000010637", "url": "https://bgee.org/?page=gene&gene_id=ENSBTAG00000010637", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "cd16161", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd16161", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "IPR000917", "url": "https://www.ebi.ac.uk/interpro/entry/IPR000917", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR017850", "url": "https://www.ebi.ac.uk/interpro/entry/IPR017850", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR024607", "url": "https://www.ebi.ac.uk/interpro/entry/IPR024607", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR050738", "url": "https://www.ebi.ac.uk/interpro/entry/IPR050738", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "HVACRCQ", "url": "https://omabrowser.org/oma/group/HVACRCQ/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "PTHR42693", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR42693", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR42693:SF42", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR42693:SF42", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00884", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00884", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF14707", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF14707", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "R-BTA-1663150", "url": "https://www.reactome.org/PathwayBrowser/#R-BTA-1663150", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "R-BTA-9840310", "url": "https://www.reactome.org/PathwayBrowser/#R-BTA-9840310", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "17261", "url": "https://www.rhea-db.org/rhea/17261", "database": "Rhea", "categories": [ "Enzyme and Pathway" ] }, { "id": "A0AAA9RT03", "url": "https://www.uniprot.org/uniprotkb/A0AAA9RT03", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0AAA9RT03-1", "url": "https://www.uniprot.org/uniprotkb/A0AAA9RT03-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "F1N665", "url": "https://www.uniprot.org/uniprotkb/F1N665", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "F1N665-1", "url": "https://www.uniprot.org/uniprotkb/F1N665-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MAWLSLKVWLVGLSFLGCLYPLVDFSFSGETRGQKPNFVIILADDMGWGDLGANWAGTKDTANLDRMAAEGTRFVDFHAAASTCSPSRAALLTGRLGLRNGVTHNFAVTSVGGLPLNETTLAEVLRGAGYVTGMIGKWHLGHHGSHHPNFRGFDYYFGVPYSHDMGCTDTPGYNHPPCPACPRGDRPSRNLERDCYSDVALPLYENLNIVEQPVNLSALAQKYAEKATQFIQQASTSGRPFLLYVGLAHMHVPLAGTPPSAGPRGQRLYSAGLREMDHLVGRIKDTVDLVAKNNTFLWFTGDNGPWAQKCELAGSVGPFTGSWQACRGGSPAKQTTWEGGHRVPALAYWPGRVPVNVTSAALLSVLDIFPTVLALAGAPLPQGRRFDGLDVSQVLFGRAQTGHRVLFHPNSGAAGEDGALQTVRLEQYKAFYVTGGARACDGSVGPERHHERPLIFDLEADLAEAAPLDRGGAEYRAVLPRVAAALAGVLADIARDRVSRADYSQDPSVRPCCDPRRPACRCRAA", "length": 525, "header": "tr|F1N665-1|F1N665_BOVIN Isoform 1 of Arylsulfatase G OS=Bos taurus OX=9913 GN=ARSG PE=3 SV=3 CANONICAL=F1N665-1" }, "isoforms": [ { "isoform_ac": "A0AAA9RT03-1", "url": "https://www.uniprot.org/uniprotkb/A0AAA9RT03/entry", "sequence": { "sequence": "MAWLSLKVWLVGLSFLGCLYPLVDFSFSGETRGQKPNFVIILADDMGWGDLGANWAGTKDTANLDRMAAEGTRFVDFHAAASTCSPSRAALLTGRLGLRNGVTHNFAVTSVGGLPLNETTLAEVLRGAGYVTGMIGKWHLGHHGSHHPNFRGFDYYFGVPYSHDMGCTDTPGYNHPPCPACPRGDRPSRNLERDCYSDVALPLYENLNIVEQPVNLSALAQKYAEKATQFIQQASTSGRPFLLYVGLAHMHVPLAGTPPSAGPRGQRLYSAGLREMDHLVGRIKDTVDLVAKNNTFLWFTGDNGPWAQKCELAGSVGPFTGSWQACRGGSPAKQTTWEGGHRVPALAYWPGRVPVNVTSAALLSVLDIFPTVLALAGAPLPQGRRFDGLDVSQVLFGRAQTGHRLAPRETIVNPLEVADGRPGGKHRSDYKDVLFHPNSGAAGEDGALQTVRLEQYKAFYVTGGARACDGSVGPERHHERPLIFDLEADLAEAAPLDRGGAEYRAVLPRVAAALAGVLADIARDRVSRADYSQDPSVRPCCDPRRPACRCRAA", "length": 553, "header": "tr|A0AAA9RT03-1|F1N665_BOVIN Computationally mapped isoform of Arylsulfatase G OS=Bos taurus OX=9913 GN=ARSG PE=3 SV=1 CANONICAL=F1N665-1" }, "locus": { "chromosome": "19", "start_pos": 61838635, "end_pos": 61783350, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000092414.1", "url": "https://www.ensembl.org/id/ENSBTAT00000092414.1" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000075895.1", "url": "https://www.ensembl.org/id/ENSBTAP00000075895.1" } ] } }, { "isoform_ac": "F1N665-1", "url": "https://www.uniprot.org/uniprotkb/F1N665/entry", "sequence": { "sequence": "MAWLSLKVWLVGLSFLGCLYPLVDFSFSGETRGQKPNFVIILADDMGWGDLGANWAGTKDTANLDRMAAEGTRFVDFHAAASTCSPSRAALLTGRLGLRNGVTHNFAVTSVGGLPLNETTLAEVLRGAGYVTGMIGKWHLGHHGSHHPNFRGFDYYFGVPYSHDMGCTDTPGYNHPPCPACPRGDRPSRNLERDCYSDVALPLYENLNIVEQPVNLSALAQKYAEKATQFIQQASTSGRPFLLYVGLAHMHVPLAGTPPSAGPRGQRLYSAGLREMDHLVGRIKDTVDLVAKNNTFLWFTGDNGPWAQKCELAGSVGPFTGSWQACRGGSPAKQTTWEGGHRVPALAYWPGRVPVNVTSAALLSVLDIFPTVLALAGAPLPQGRRFDGLDVSQVLFGRAQTGHRVLFHPNSGAAGEDGALQTVRLEQYKAFYVTGGARACDGSVGPERHHERPLIFDLEADLAEAAPLDRGGAEYRAVLPRVAAALAGVLADIARDRVSRADYSQDPSVRPCCDPRRPACRCRAA", "length": 525, "header": "tr|F1N665-1|F1N665_BOVIN Isoform 1 of Arylsulfatase G OS=Bos taurus OX=9913 GN=ARSG PE=3 SV=3 CANONICAL=F1N665-1" }, "locus": { "chromosome": "19", "start_pos": 61838635, "end_pos": 61783350, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000014061.7", "url": "https://www.ensembl.org/id/ENSBTAT00000014061.7" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000014061.6", "url": "https://www.ensembl.org/id/ENSBTAP00000014061.6" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [ "enzyme" ], "publication": [], "pathway": [ { "id": "R-BTA-1663150", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-BTA-1663150", "resource": "Reactome", "description": "The activation of arylsulfatases" }, { "id": "R-BTA-9840310", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-BTA-9840310", "resource": "Reactome", "description": "Glycosphingolipid catabolism" } ], "orthologs": [ { "uniprot_canonical_ac": "A0A8C2LGS6-1", "protein_name": "Arylsulfatase G", "gene_name": "Arsg", "tax_id": 10029, "organism": "Cricetulus griseus", "sequence": { "sequence": "MGWLFLKVLLAGMTFSGLLYPLLDLSISGKTRAPKPNIVIILADDMGWGDLGANWAETKDTTNLDKMASEGMRFVDFHAAASTCSPSRASLLTGRLGLRNGVTHNFAVTSVGGLPLNETTLAEVLQQAGYVTAMIGKWHLGHHGSYHPNFRGFDYYFGIPYSHDMGCTDTPGYNYPPCPACPQSDGLWRNPERDCYTDVALPLYENLNIVEQPVNLSGLARKYLEKAVAFIEQASTSGRPFLLYMGLAHMHVPLSVTPPLENPGSQRPYRASLQEMDSLVGQIKDKVDHMAKENTLLWITGDNGPWAQKCELAGSVGPFFGLWQTHQGGSSAKQTTWEGGHRVPALAYWPGRVPANATSTALLSMLDIFPTAIALAGASLPPNRNFDGLDVSEVLFGRSQVGHRVLFHPNSGAAGEYGGLQTVRLDHHKAFYITGGAKACDGSTGPEQLHASPLIFNLEDDAAEAAPLQRGSPEYQAVLPKVTRVLADVLQDIADDNSSRADYSQDPSVTPCCSPSQIACRCQTV", "length": 525 }, "evidence": [ { "id": "F1N665", "url": "https://omabrowser.org/oma/group/F1N665/", "database": "OMA" } ], "glygen_name": "Hamster", "common_name": "Chinese hamster" }, { "uniprot_canonical_ac": "A0A8V1AI26-1", "protein_name": "Arylsulfatase G", "gene_name": "ARSG", "tax_id": 9031, "organism": "Gallus gallus", "sequence": { "sequence": "MGTPAPWSVLLLAVLVGLCTSPVAQGKPNFIVILADDLGWGDLGANWAETKETPHLDELAAEGTRFVDFHSAASTCSPSRASLLTGRLGVRNGVTHNFAISSVGGLPLNETTLAEVLRAAGYSTAAIGKWHLGHHGHHHPIFRGFDYYFGIPYSHDMGCTDTPGYNVPPCPPCPQHSAATSPTNKDCYTDVALPLFENLTIIQQPVDLSSLVEQYMEAAARFIQQARDSSRPFFLYLALAHMHVPLQIAPPPDRGIYGAALREMDALVGHVKHLADSCGKGSTLLWFTGDNGPWMQKCELAGRLGPLLGAWQRAQGGSPAKQTTWEGGHRVPALAYWPGHVPAKRSSHAMLSTLDVFPTLVALAGATLPPNRRFDGMDVSPVLFGLSDVGHKVLLHPNSGAAGKDGAVEALRLAQYKAFYTTGGAKACDGSIGPEEHHRPPLIFNLDRDIQEQEPLDVASREYQAVLPAISRAYAQALEDIATDNTTVADYSKDPAAVPCCSTQHVACRCHAPTSHTASLDQHTDGRATRLCLSDRSLKPLLDESPNCSALRKQRSPVKFRTSKHPNQGSLCTTQREPAPHQRAEQMQNTLLPAMEEKPES", "length": 601 }, "evidence": [ { "id": "F1N665", "url": "https://omabrowser.org/oma/group/F1N665/", "database": "OMA" } ], "glygen_name": "Chicken", "common_name": "Chicken" }, { "uniprot_canonical_ac": "Q32KJ9-1", "protein_name": "Arylsulfatase G", "gene_name": "Arsg", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MGWLFLKVLLVGMVFSGLLYPFVDFSISGETRAPRPNIVIILADDMGWGDLGANWAETKDTTNLDKMASEGMRFVDFHAAASTCSPSRASLLTGRLGLRNGVTHNFAVTSVGGLPLNETTLAEVLQQAGYVTAMIGKWHLGHHGSYHPSFRGFDYYFGIPYSNDMGCTDNPGYNYPPCPACPQSDGRWRNPDRDCYTDVALPLYENLNIVEQPVNLSGLAQKYAERAVEFIEQASTSGRPFLLYVGLAHMHVPLSVTPPLANPQSQRLYRASLQEMDSLVGQIKDKVDHVAKENTLLWFAGDNGPWAQKCELAGSMGPFSGLWQTHQGGSPAKQTTWEGGHRVPALAYWPGRVPVNVTSTALLSLLDIFPTVIALAGASLPPNRKFDGVDVSEVLFGKSQTGHRVLFHPNSGAAGEYGALQTVRLDRYKAFYITGGAKACDGGVGPEQHHVSPLIFNLEDDAAESSPLQKGSPEYQELLPKVTRVLADVLQDIADDNSSQADYTQDPSVTPCCNPYQITCRCQPGE", "length": 526 }, "evidence": [ { "id": "F1N665", "url": "https://omabrowser.org/oma/group/F1N665/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "Q3TYD4-1", "protein_name": "Arylsulfatase G", "gene_name": "Arsg", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MGWLFLKVLLVGMAFSGFFYPLVDFSISGKTRAPQPNIVIILADDMGWGDLGANWAETKDTTNLDKMASEGMRFVDFHAAASTCSPSRASLLTGRLGLRNGVTHNFAVTSVGGLPVNETTLAEVLRQEGYVTAMIGKWHLGHHGSYHPNFRGFDYYFGIPYSNDMGCTDAPGYNYPPCPACPQRDGLWRNPGRDCYTDVALPLYENLNIVEQPVNLSGLAQKYAERAVEFIEQASTSGRPFLLYVGLAHMHVPLSVTPPLAHPQRQSLYRASLREMDSLVGQIKDKVDHVARENTLLWFTGDNGPWAQKCELAGSVGPFFGLWQTHQGGSPTKQTTWEGGHRVPALAYWPGRVPANVTSTALLSLLDIFPTVIALAGASLPPNRKFDGRDVSEVLFGKSQMGHRVLFHPNSGAAGEYGALQTVRLNHYKAFYITGGAKACDGSVGPEQHHVAPLIFNLEDAADEGMPLQKGSPEYQEVLQQVTRALADVLQDIADDNSSRADYTQDPSVIPCCNPYQTTCRCQPV", "length": 525 }, "evidence": [ { "id": "F1N665", "url": "https://omabrowser.org/oma/group/F1N665/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q96EG1-1", "protein_name": "Arylsulfatase G", "gene_name": "ARSG", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MGWLFLKVLLAGVSFSGFLYPLVDFCISGKTRGQKPNFVIILADDMGWGDLGANWAETKDTANLDKMASEGMRFVDFHAAASTCSPSRASLLTGRLGLRNGVTRNFAVTSVGGLPLNETTLAEVLQQAGYVTGIIGKWHLGHHGSYHPNFRGFDYYFGIPYSHDMGCTDTPGYNHPPCPACPQGDGPSRNLQRDCYTDVALPLYENLNIVEQPVNLSSLAQKYAEKATQFIQRASTSGRPFLLYVALAHMHVPLPVTQLPAAPRGRSLYGAGLWEMDSLVGQIKDKVDHTVKENTFLWFTGDNGPWAQKCELAGSVGPFTGFWQTRQGGSPAKQTTWEGGHRVPALAYWPGRVPVNVTSTALLSVLDIFPTVVALAQASLPQGRRFDGVDVSEVLFGRSQPGHRVLFHPNSGAAGEFGALQTVRLERYKAFYITGGARACDGSTGPELQHKFPLIFNLEDDTAEAVPLERGGAEYQAVLPEVRKVLADVLQDIANDNISSADYTQDPSVTPCCNPYQIACRCQAA", "length": 525 }, "evidence": [ { "id": "F1N665", "url": "https://omabrowser.org/oma/group/F1N665/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" } ], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 3, "go_terms": [ { "name": "extracellular space", "id": "GO:0005615", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005615", "evidence": [ { "database": "UniProtKB", "id": "F1N665", "url": "https://www.uniprot.org/uniprotkb/F1N665" } ], "pmid": "" }, { "name": "endoplasmic reticulum", "id": "GO:0005783", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005783", "evidence": [ { "database": "UniProtKB", "id": "F1N665", "url": "https://www.uniprot.org/uniprotkb/F1N665" } ], "pmid": "" }, { "name": "lysosome", "id": "GO:0005764", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005764", "evidence": [ { "database": "UniProtKB", "id": "F1N665", "url": "https://www.uniprot.org/uniprotkb/F1N665" } ], "pmid": "" } ] }, { "name": "Molecular Function", "total": 3, "go_terms": [ { "name": "metal ion binding", "id": "GO:0046872", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0046872", "evidence": [ { "database": "UniProtKB", "id": "F1N665", "url": "https://www.uniprot.org/uniprotkb/F1N665" } ], "pmid": "" }, { "name": "arylsulfatase activity", "id": "GO:0004065", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0004065", "evidence": [ { "database": "UniProtKB", "id": "F1N665", "url": "https://www.uniprot.org/uniprotkb/F1N665" } ], "pmid": "" }, { "name": "N-sulfoglucosamine-3-sulfatase activity", "id": "GO:0033889", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0033889", "evidence": [ { "database": "UniProtKB", "id": "F1N665", "url": "https://www.uniprot.org/uniprotkb/F1N665" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 1, "go_terms": [ { "name": "sulfur compound metabolic process", "id": "GO:0006790", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006790", "evidence": [ { "database": "UniProtKB", "id": "F1N665", "url": "https://www.uniprot.org/uniprotkb/F1N665" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 117, "end_pos": 119, "annotation": "n_glycosylation_sequon" }, { "start_pos": 215, "end_pos": 217, "annotation": "n_glycosylation_sequon" }, { "start_pos": 293, "end_pos": 295, "annotation": "n_glycosylation_sequon" }, { "start_pos": 356, "end_pos": 358, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [ { "id": "17261", "name": "", "equation": "an aryl sulfate + H2O = a phenol + sulfate + H(+)", "summary": "", "cellular_location": "", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [ "E1BGL6-1", "E1BIY5-1", "Q148F3-1", "F1N665-1" ], "evidence": [ { "id": "17261", "database": "Rhea", "url": "https://www.rhea-db.org/rhea/17261" } ] }, { "id": "R-BTA-1614362", "name": "SUMF1 mediates the oxidation of cysteine to formylglycine, producing active arylsulfatases", "equation": "", "summary": "This event has been computationally inferred from an event that has been demonstrated in another species.

The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.

More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "cellular_location": "endoplasmic reticulum lumen", "input_participant_list": [ "R-ALL-194653" ], "output_participant_list": [ "R-ALL-1663154" ], "enzyme_list": [ "F1N665-1", "Q08DD1-1", "Q0P5L5-1", "Q148F3-1" ], "evidence": [ { "id": "R-BTA-1614362", "database": "Reactome", "url": "https://www.reactome.org/PathwayBrowser/#R-BTA-1614362" } ] } ], "reaction_participants": [ { "participant_id": "R-ALL-1663154", "participant_name": "H2S [endoplasmic reticulum lumen]", "crossref": [ { "id": "29919", "database": "ChEBI", "url": "" } ] }, { "participant_id": "R-ALL-194653", "participant_name": "NAD+ [endoplasmic reticulum lumen]", "crossref": [ { "id": "57540", "database": "ChEBI", "url": "" }, { "id": "ZINC000008214766", "database": "ZINC", "url": "" }, { "id": "C00003", "database": "COMPOUND", "url": "" } ] } ], "reaction_enzymes": [ { "uniprot_ac": "E1BGL6", "gene_name": "SULF1", "activity": [ { "ec_number": "3.1.6.14", "activity": "Hydrolysis of the 6-sulfate groups of the N-acetyl-D-glucosamine 6-sulfate units of heparan sulfate and keratan sulfate.", "evidence": [ { "id": "E1BGL6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BGL6" } ] }, { "ec_number": "3.1.6.1", "activity": "an aryl sulfate + H2O = a phenol + sulfate + H(+).", "evidence": [ { "id": "E1BGL6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BGL6" } ] }, { "ec_number": "3.1.6.14", "activity": "", "evidence": [ { "id": "E1BGL6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BGL6" } ] }, { "ec_number": "3.1.6.1", "activity": "", "evidence": [ { "id": "E1BGL6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BGL6" } ] }, { "ec_number": "3.1.6.-", "activity": "", "evidence": [ { "id": "E1BGL6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BGL6" } ] } ] }, { "uniprot_ac": "E1BIY5", "gene_name": "SULF2", "activity": [ { "ec_number": "3.1.6.14", "activity": "Hydrolysis of the 6-sulfate groups of the N-acetyl-D-glucosamine 6-sulfate units of heparan sulfate and keratan sulfate.", "evidence": [ { "id": "E1BIY5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BIY5" } ] }, { "ec_number": "3.1.6.1", "activity": "an aryl sulfate + H2O = a phenol + sulfate + H(+).", "evidence": [ { "id": "E1BIY5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BIY5" } ] }, { "ec_number": "3.1.6.1", "activity": "", "evidence": [ { "id": "E1BIY5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BIY5" } ] }, { "ec_number": "3.1.6.14", "activity": "", "evidence": [ { "id": "E1BIY5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BIY5" } ] } ] }, { "uniprot_ac": "F1N665", "gene_name": "ARSG", "activity": [ { "ec_number": "3.1.6.1", "activity": "an aryl sulfate + H2O = a phenol + sulfate + H(+).", "evidence": [ { "id": "F1N665", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1N665" } ] }, { "ec_number": "3.1.6.15", "activity": "Hydrolysis of the 3-sulfate groups of the N-sulfo-D-glucosamine 3-O-sulfate units of heparin.", "evidence": [ { "id": "F1N665", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1N665" } ] }, { "ec_number": "3.1.6.15", "activity": "", "evidence": [ { "id": "F1N665", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1N665" } ] }, { "ec_number": "3.1.6.1", "activity": "", "evidence": [ { "id": "F1N665", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1N665" } ] } ] }, { "uniprot_ac": "Q08DD1", "gene_name": "ARSA", "activity": [ { "ec_number": "3.1.6.8", "activity": "an N-acyl-1-beta-D-(3-O-sulfo)-galactosyl-sphing-4-enine + H2O = a beta-D-galactosyl-(1<->1')-N-acylsphing-4-enine + sulfate + H(+).", "evidence": [ { "id": "Q08DD1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q08DD1" } ] }, { "ec_number": "3.1.6.8", "activity": "", "evidence": [ { "id": "Q08DD1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q08DD1" } ] } ] }, { "uniprot_ac": "Q0P5L5", "gene_name": "SUMF1", "activity": [ { "ec_number": "1.8.3.7", "activity": "L-cysteinyl-[sulfatase] + 2 a thiol + O2 = an organic disulfide + 3-oxo-L-alanyl-[sulfatase] + hydrogen sulfide + H2O + H(+).", "evidence": [ { "id": "Q0P5L5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q0P5L5" } ] }, { "ec_number": "1.8.3.7", "activity": "", "evidence": [ { "id": "Q0P5L5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q0P5L5" } ] } ] }, { "uniprot_ac": "Q148F3", "gene_name": "ARSK", "activity": [ { "ec_number": "3.1.6.1", "activity": "an aryl sulfate + H2O = a phenol + sulfate + H(+).", "evidence": [ { "id": "Q148F3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q148F3" } ] }, { "ec_number": "3.1.6.18", "activity": "Hydrolysis of the 2-sulfate groups of the 2-O-sulfo-D-glucuronate residues of chondroitin sulfate, heparin and heparitin sulfate.", "evidence": [ { "id": "Q148F3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q148F3" } ] }, { "ec_number": "3.1.6.1", "activity": "", "evidence": [ { "id": "Q148F3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q148F3" } ] } ] } ], "biomarkers": [], "structures": [ { "pdb_id": "AF-F1N665-F1", "pdb_chain": "global", "start_pos": 1, "end_pos": 525, "overlap": "1.0", "method": "AlphaFold", "type": "alphafold", "resolution": -1.0, "url": "https://data.glygen.org/ln2downloads/pdb/current/AF-F1N665-F1.pdb", "url_external": "https://alphafold.ebi.ac.uk/entry/F1N665" } ], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "F1N665", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1N665" }, { "id": "PF00884", "database": "Pfam", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00884" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "Sulfatase N-terminal", "eco_id": "ECO_0000259", "start_pos": 36, "end_pos": 378, "start_aa": "Pro", "end_aa": "Ala", "glycosite_overlap": [] } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [ { "ec_number": "3.1.6.1", "ec_name": "an aryl sulfate + H2O = a phenol + sulfate + H(+).", "evidence": [ { "id": "3.1.6.1", "database": "Rhea", "url": "https://www.rhea-db.org/rhea/?query=ec:3.1.6.1" }, { "id": "3.1.6.1", "database": "BRENDA Enzymes", "url": "https://www.brenda-enzymes.org/enzyme.php?ecno=3.1.6.1" } ] }, { "ec_number": "3.1.6.15", "ec_name": "Hydrolysis of the 3-sulfate groups of the N-sulfo-D-glucosamine 3-O-sulfate units of heparin.", "evidence": [] } ], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" }, { "name": "homologset.oma", "label": "OMA Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 117, "end_pos": 119 }, { "start_pos": 215, "end_pos": 217 }, { "start_pos": 293, "end_pos": 295 }, { "start_pos": 356, "end_pos": 358 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ], "tool_support": { "graph_view": "yes" } }, { "uniprot_canonical_ac": "F6RF21-1", "uniprot_ac": "F6RF21", "uniprot_id": "F6RF21_BOVIN", "mass": { "chemical_mass": 225594.0, "monoisotopic_mass": 225594.0 }, "refseq": {}, "gene_names": [ { "name": "SMCHD1", "type": "recommended", "evidence": [ { "id": "F6RF21", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F6RF21" } ] } ], "protein_names": [ { "name": "Structural maintenance of chromosomes flexible hinge domain-containing protein 1", "type": "recommended", "evidence": [ { "id": "F6RF21", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F6RF21/entry#names_and_taxonomy" } ] } ], "function": [], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Bos taurus", "taxid": 9913, "evidence": [ { "database": "UniProtKB", "id": "F6RF21", "url": "https://www.uniprot.org/uniprotkb/F6RF21" } ], "common_name": "Bovine", "glygen_name": "Bovine", "reference_species": "Bos taurus [9913]" } ], "gene": [ { "name": "SMCHD1", "url": "https://www.uniprot.org/uniprotkb/F6RF21", "locus": { "chromosome": "24", "start_pos": 37057011, "end_pos": 36928926, "strand": "-", "evidence": [ { "database": "Ensembl Gene", "id": "ENSBTAG00000003354", "url": "https://www.ensembl.org/id/ENSBTAG00000003354" } ] } } ], "crossref": [ { "id": "ENSBTAG00000003354", "url": "https://bgee.org/?page=gene&gene_id=ENSBTAG00000003354", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "cd16937", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd16937", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "537894", "url": "https://www.ncbi.nlm.nih.gov/gene/537894", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR010935", "url": "https://www.ebi.ac.uk/interpro/entry/IPR010935", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR036277", "url": "https://www.ebi.ac.uk/interpro/entry/IPR036277", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR036890", "url": "https://www.ebi.ac.uk/interpro/entry/IPR036890", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR038892", "url": "https://www.ebi.ac.uk/interpro/entry/IPR038892", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR055109", "url": "https://www.ebi.ac.uk/interpro/entry/IPR055109", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR058611", "url": "https://www.ebi.ac.uk/interpro/entry/IPR058611", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR058612", "url": "https://www.ebi.ac.uk/interpro/entry/IPR058612", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR058613", "url": "https://www.ebi.ac.uk/interpro/entry/IPR058613", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR058614", "url": "https://www.ebi.ac.uk/interpro/entry/IPR058614", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR058615", "url": "https://www.ebi.ac.uk/interpro/entry/IPR058615", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR058616", "url": "https://www.ebi.ac.uk/interpro/entry/IPR058616", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR058617", "url": "https://www.ebi.ac.uk/interpro/entry/IPR058617", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "F6RF21", "url": "https://www.orthodb.org/?gene=F6RF21", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR22640", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR22640", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR22640:SF2", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR22640:SF2", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF06470", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF06470", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF13589", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF13589", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF22899", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF22899", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF26194", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF26194", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF26195", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF26195", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF26196", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF26196", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF26197", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF26197", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF26198", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF26198", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF26199", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF26199", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF26201", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF26201", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "13065", "url": "https://www.rhea-db.org/rhea/13065", "database": "Rhea", "categories": [ "Enzyme and Pathway" ] }, { "id": "A0AAA9RTW0", "url": "https://www.uniprot.org/uniprotkb/A0AAA9RTW0", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0AAA9RTW0-1", "url": "https://www.uniprot.org/uniprotkb/A0AAA9RTW0-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0AAA9TBL7", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TBL7", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0AAA9TBL7-1", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TBL7-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "F6RF21", "url": "https://www.uniprot.org/uniprotkb/F6RF21", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "F6RF21-1", "url": "https://www.uniprot.org/uniprotkb/F6RF21-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MAAAGGGGPSVETGEGGGGDGPRTVYLFDRREKESELGDRALQVEERSDFAAFRASVCQTLGISPGEKFVITTTSRKEITCDNFDETVKDGVTLYLLQSVNQLLLTATKERIDFLPHYDTLVKSGMYEYYASEGQNPLPFALAELIDNSLSATSRNNGVRRIQIKLHFDETQGKPAVAVIDNGRGMTSKQLNNWAVYRLSKFTRQGDFESDHSGYVRPLPVPRSLNSDISYFGVGGKQAVFFVGQSARMISKPADSQDVHELLLSKEDFEKREKNKEAIYSGFIRNRKPSDSSHITNDDERFLQHLIAEEKEKDSFTAVVITGVQPEHIQYLKNYFHLWTRQLTHIYHYYIHGPKGNEQRTSKEAGPFNNIDIEISMFEKGKTPKIINLREIQDDMQTLYINTAADSFEFKAHVEGDGVVEGIIRYHPFLYDRETYPDDPCFPSKLKDEDDDDDCFILEKAARGKRPIFECFWNGRLIPYTSVEDFDWCTPPKKRGLAPFECYNRISGALFTNDKFQVSTNKLTFMDLELKLKDKNTLFTRILNGQEQRMKIDREFALWLKDCHEKYDKQIKFTLFKGVITRPDLPSKKQGPWATYSAIEWDGKIYKAGQLVKTIKTLPLFYGSIVKFFLYGDHDGEVYATGGEVQIAMEPQALYDEIKTVPIAKLDRTVAEKAVKKYVEDEMARLPDRLSVTWPEGDELLPNEIRPAGTPIGALRIEILNKKGETMQKLPGTSHGGSKKLLVELKVILHSSSGNKEIISHISQHGGKWPYWFKKMENIHKLGNYTLKLQVVLNESNADTYAGRPLPSKAIKFSVKEGKPEKFSFGLLDPPFRVGVPFNIPVEFQDEFGHTSQLSTDIQPIFEASGLTLHYDEITKGPNCVIRGVTAKGPVNSCQGKVSINFNLKVILPGLKEDSQILKIRLLPGPPRRLKVKPDSEILVIENGTAFPFQVEVLDESDNITAQPKLIVHCKFSGAPNLPIYVVDCSSSGTSILSGPAIQVQNIKKDQTLKAKIEIPSCKDVAPVEKTIKLLPSSHVARLQIFSVEGQKAIQIKHQDEVNWIAGDVMHNLIFQMYDEGEREIHITSALSEKIKVNWTPEINKEHLLQGLLPDVQVPTSVKDMRYCQVSFQDDHVSLESAFTVRPLPDEPKHLKCELKGGKTVQMGQELQGEIVITVTDQYGNQIQAFSPSSLSALGIAGIGLDSSHLKTTFQENTQSINVKGIRFIPGPPGNKDLCFTWREFSDFIRVQLVSGPPAKLLLVDWPELKESIPVINGRELQNPLIVQLCDQWDNPAPVPQVKISLVKANNLKLTPSNQQHKTDERGRANFGVFSVLAPRGEHNMQVKAIYNKNTIEGPIIKLMILPDPEKPIRLNVKYDKDASFLAGGIFTDFMITVISEDDSIIKNINPARISMKMWKLANSGNRPPANAEIFSCNKIKDNDKEDGCFYFRDKAVPNKVGTYCIQFGFTMDKTNILNSEQIIVDVLPNQPVKLVPEIQPATPAVSNVRSVASRTLVKDLYLHITDDYNNHTGVDLVGTVMATIKGSNEEDDIPLFNGKIRTLEFPFVKGSAEITSLVLAENSPGRDSTEYFIVFEPRLPALSRTLESYILPFMFYNDVKKQQQMAALTKEKDQLSKSITVYRTLFDTSKQLLDEMKCQVEEAKLKEAQLRNELKKHNIDISTTQQVPHIEALLKRKLSEQEELKKKPRRSCTLPNYTKGSGDVLGKIAHLAQIEDDRAAMVISWHLASDMDCVVTLTTDAARRIYDETQGRQQVLPLDSIYKKTLPDWKRPLPHYRNGKLYFKPIGDPVFARDLLTFPDNVEHCETVFGMLLGDTIILDNLDAANHYRKEVVKITHCPTLLTRDGDRIRSNGKFGGLQNKAPPMDKLRGMVFGAPVPKQCLILGEQIDLLQQYRTAVCRLGSVNEDLNGQLKYLHTPDMKRKKQELDEHEKNLKLIEQKLGMTPTRKCNDSLPHPMTDCPVPPKRIRREAARQNRIITKTDV", "length": 2000, "header": "tr|F6RF21-1|F6RF21_BOVIN Isoform 1 of Structural maintenance of chromosomes flexible hinge domain-containing protein 1 OS=Bos taurus OX=9913 GN=SMCHD1 PE=3 SV=3 CANONICAL=F6RF21-1" }, "isoforms": [ { "isoform_ac": "A0AAA9RTW0-1", "url": "https://www.uniprot.org/uniprotkb/A0AAA9RTW0/entry", "sequence": { "sequence": "MAAAGGGGPSVETGEGGGGDGPRTVYLFDRREKESELGDRALQVEERSDFAAFRASVCQTLGISPGEKFVITTTSRKEITCDNFDETVKDGVTLYLLQSVNQLLLTATKERIDFLPHYDTLVKSGMYEYYASEGQNPLPFALAELIDNSLSATSRNNGVRRIQIKLHFDETQGKPAVAVIDNGRGMTSKQLNNWAVYRLSKFTRQGDFESDHSGYVRPLPVPRSLNSDISYFGVGGKQAVFFVGQSARMISKPADSQDVHELLLSKEDFEKREKNKEAIYSGFIRNRKPSDSSHITNDDERFLQHLIAEEKEKDSFTAVVITGVQPEHIQYLKNYFHLWTRQLTHIYHYYIHGPKGNEQRTSKEAGPFNNIDIEISMFEKGKTPKIINLREIQDDMQTLYINTAADSFEFKAHVEGDGVVEGIIRYHPFLYDRETYPDDPCFPSKLKDEDDDDDCFILEKAARGKRPIFECFWNGRLIPYTSVEDFDWCTPPKKRGLAPFECYNRISGALFTNDKFQVSTNKLTFMDLELKLKDKNTLFTRILNGQEQRMKIDREFALWLKDCHEKYDKQIKFTLFKGVITRPDLPSKKQGPWATYSAIEWDGKIYKAGQLVKTIKTLPLFYGSIVKFFLYGDHDGEVYATGGEVQIAMEPQALYDEIKTVPIAKLDRTVAEKAVKKYVEDEMARLPDRLSVTWPEGDELLPNEIRPAGTPIGALRIEILNKKGETMQKLPGTSHGGSKKLLVELKVILHSSSGNKEIISHISQHGGKWPYWFKKMENIHKLGNYTLKLQVVLNESNADTYAGRPLPSKAIKFSVKEGKPEKFSFGLLDPPFRVGVPFNIPVEFQDEFGHTSQLSTDIQPIFEASGLTLHYDEITKGPNCVIRGVTAKGPVNSCQGKNFNLKVILPGLKEDSQILKIRLLPGPPRRLKVKPDSEILVIENGTAFPFQVEVLDESDNITAQPKLIVHCKFSGAPNLPIYVVDCSSSGTSILSGPAIQVQNIKKDQTLKAKIEIPSCKDVAPVEKTIKLLPSSHVARLQIFSVEGQKAIQIKHQDEVNWIAGDVMHNLIFQMYDEGEREIHITSALSEKIKVNWTPEINKEHLLQGLLPDVQVPTSVKDMRYCQVSFQDDHVSLESAFTVRPLPDEPKHLKCELKGGKTVQMGQELQGEIVITVTDQYGNQIQAFSPSSLSALGIAGIGLDSSHLKTTFQENTQSINVKGIRFIPGPPGNKDLCFTWREFSDFIRVQLVSGPPAKLLLVDWPELKESIPVINGRELQNPLIVQLCDQWDNPAPVPQVKISLVKANNLKLTPSNQQHKTDERGRANFGVFSVLAPRGEHNMQVKAIYNKNTIEGPIIKLMILPDPEKPIRLNVKYDKDASFLAGGIFTDFMITVISEDDSIIKNINPARISMKMWKLANSGNRPPANAEIFSCNKIKDNDKEDGCFYFRDKAVPNKVGTYCIQFGFTMDKTNILNSEQIIVDVLPNQPVKLVPEIQPATPAVSNVRSVASRTLVKDLYLHITDDYNNHTGVDLVGTVMATIKGSNEEDDIPLFNGKIRTLEFPFVKGSAEITSLVLAENSPGRDSTEYFIVFEPRLPALSRTLESYILPFMFYNDVKKQQQMAALTKEKDQLSKSITVYRTLFDTSKQLLDEMKCQVEEAKLKEAQLRNELKKHNIDISTTQQVPHIEALLKRKLSEQEELKKKPRRSCTLPNYTKGSGDVLGKIAHLAQIEDDRAAMVISWHLASDMDCVVTLTTDAARRIYDETQGRQQVLPLDSIYKKTLPDWKRPLPHYRNGKLYFKPIGDPVFARDLLTFPDNVEHCETVFGMLLGDTIILDNLDAANHYRKEVVKITHCPTLLTRDGDRIRSNGKFGGLQNKAPPMDKLRGMVFGAPVPKQCLILGEQIDLLQQYRTAVCRLGSVNEDLNGQLKYLHTPDMKRKKQELDEHEKNLKLIEQKLGMTPTRKCNDSLPHPMTDCPVPPKRIRREAARQNRVNFFYEELLGVPLWPSS", "length": 2007, "header": "tr|A0AAA9RTW0-1|F6RF21_BOVIN Computationally mapped isoform of Structural maintenance of chromosomes flexible hinge domain-containing protein 1 OS=Bos taurus OX=9913 GN=SMCHD1 PE=3 SV=1 CANONICAL=F6RF21-1" }, "locus": { "chromosome": "24", "start_pos": 37056007, "end_pos": 36929125, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000090941.2", "url": "https://www.ensembl.org/id/ENSBTAT00000090941.2" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000075444.1", "url": "https://www.ensembl.org/id/ENSBTAP00000075444.1" } ] } }, { "isoform_ac": "A0AAA9TBL7-1", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TBL7/entry", "sequence": { "sequence": "MAAAGGGGPSVETGEGGGGDGPRTVYLFDRREKESELGDRALQVEERSDFAAFRASVCQTLGISPGEKFVITTTSRKEITCDNFDETVKDGVTLYLLQSVNQLLLTATKERIDFLPHYDTLVKSGMYEYYASEGQNPLPFALAELIDNSLSATSRNNGVRRIQIKLHFDETQGKPAVAVIDNGRGMTSKQLNNWAVYRLSKFTRQGDFESDHSGYVRPLPVPRSLNSDISYFGVGGKQAVFFVGQSARMISKPADSQDVHELLLSKEDFEKREKNKEAIYSGFIRNRKPSDSSHITNDDERFLQHLIAEEKEKDSFTAVVITGVQPEHIQYLKNYFHLWTRQLTHIYHYYIHGPKGNEQRTSKEAGPFNNIDIEISMFEKGKTPKIINLREIQDDMQTLYINTAADSFEFKAHVEGDGVVEGIIRYHPFLYDRETYPDDPCFPSKLKDEDDDDDCFILEKAARGKRPIFECFWNGRLIPYTSVEDFDWCTPPKKRGLAPFECYNRISGALFTNDKFQVSTNKLTFMDLELKLKDKNTLFTRILNGQEQRMKIDREFALWLKDCHEKYDKQIKFTLFKGVITRPDLPSKKQGPWATYSAIEWDGKIYKAGQLVKTIKTLPLFYGSIVKFFLYGDHDGEVYATGGEVQIAMEPQALYDEIKTVPIAKLDRTVAEKAVKKYVEDEMARLPDRLSVTWPEGDELLPNEIRPAGTPIGALRIEILNKKGETMQKLPGTSHGGSKKLLVELKVILHSSSGNKEIISHISQHGGKWPYWFKKMENIHKLGNYTLKLQVVLNESNADTYAGRPLPSKAIKFSVKEGKPEKFSFGLLDPPFRVGVPFNIPVEFQDEFGHTSQLSTDIQPIFEASGLTLHYDEITKGPNCVIRGVTAKGPVNSCQGKNFNLKVILPGLKEDSQILKIRLLPGPPRRLKVKPDSEILVIENGTAFPFQVEVLDESDNITAQPKLIVHCKFSGAPNLPIYVVDCSSSGTSILSGPAIQVQNIKKDQTLKAKIEIPSCKDVAPVEKTIKLLPSSHVARLQIFSVEGQKAIQIKHQDEVNWIAGDVMHNLIFQMYDEGEREIHITSALSEKIKVNWTPEINKEHLLQGLLPDVQVPTSVKDMRYCQVSFQDDHVSLESAFTVRPLPDEPKHLKCELKGGKTVQMGQELQGEIVITVTDQYGNQIQAFSPSSLSALGIAGIGLDSSHLKTTFQENTQSINVKGIRFIPGPPGNKDLCFTWREFSDFIRVQLVSGPPAKLLLVDWPELKESIPVINGRELQNPLIVQLCDQWDNPAPVPQVKISLVKANNLKLTPSNQQHKTDERGRANFGVFSVLAPRGEHNMQVKAIYNKNTIEGPIIKLMILPDPEKPIRLNVKYDKDASFLAGGIFTDFMITVISEDDSIIKNINPARISMKMWKLANSGNRPPANAEIFSCNKIKDNDKEDGCFYFRDKAVPNKVGTYCIQFGFTMDKTNILNSEQDDYNNHTGVDLVGTVMATIKGSNEEDDIPLFNGKIRTLEFPFVKGSAEITSLVLAENSPGRDSTEYFIVFEPRLPALSRTLESYILPFMFYNDVKKQQQMAALTKEKDQLSKSITVYRTLFDTSKQLLDEMKCQVEEAKLKEAQLRNELKKHNIDISTTQQVPHIEALLKRKLSEQEELKKKPRRSCTLPNYTKGSGDVLGKIAHLAQIEDDRAAMVISWHLASDMDCVVTLTTDAARRIYDETQGRQQVLPLDSIYKKTLPDWKRPLPHYRNGKLYFKPIGDPVFARDLLTFPDNVEHCETVFGMLLGDTIILDNLDAANHYRKEVVKITHCPTLLTRDGDRIRSNGKFGGLQNKAPPMDKLRGMVFGAPVPKQCLILGEQIDLLQQYRTAVCRLGSVNEDLNGQLKYLHTPDMKRKKQELDEHEKNLKLIEQKLGMTPTRKCNDSLPHPMTDCPVPPKRIRREAARQNRIITKTDV", "length": 1953, "header": "tr|A0AAA9TBL7-1|F6RF21_BOVIN Computationally mapped isoform of Structural maintenance of chromosomes flexible hinge domain-containing protein 1 OS=Bos taurus OX=9913 GN=SMCHD1 PE=3 SV=1 CANONICAL=F6RF21-1" }, "locus": { "chromosome": "24", "start_pos": 37053536, "end_pos": 36929125, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000108541.2", "url": "https://www.ensembl.org/id/ENSBTAT00000108541.2" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000096114.1", "url": "https://www.ensembl.org/id/ENSBTAP00000096114.1" } ] } }, { "isoform_ac": "F6RF21-1", "url": "https://www.uniprot.org/uniprotkb/F6RF21/entry", "sequence": { "sequence": "MAAAGGGGPSVETGEGGGGDGPRTVYLFDRREKESELGDRALQVEERSDFAAFRASVCQTLGISPGEKFVITTTSRKEITCDNFDETVKDGVTLYLLQSVNQLLLTATKERIDFLPHYDTLVKSGMYEYYASEGQNPLPFALAELIDNSLSATSRNNGVRRIQIKLHFDETQGKPAVAVIDNGRGMTSKQLNNWAVYRLSKFTRQGDFESDHSGYVRPLPVPRSLNSDISYFGVGGKQAVFFVGQSARMISKPADSQDVHELLLSKEDFEKREKNKEAIYSGFIRNRKPSDSSHITNDDERFLQHLIAEEKEKDSFTAVVITGVQPEHIQYLKNYFHLWTRQLTHIYHYYIHGPKGNEQRTSKEAGPFNNIDIEISMFEKGKTPKIINLREIQDDMQTLYINTAADSFEFKAHVEGDGVVEGIIRYHPFLYDRETYPDDPCFPSKLKDEDDDDDCFILEKAARGKRPIFECFWNGRLIPYTSVEDFDWCTPPKKRGLAPFECYNRISGALFTNDKFQVSTNKLTFMDLELKLKDKNTLFTRILNGQEQRMKIDREFALWLKDCHEKYDKQIKFTLFKGVITRPDLPSKKQGPWATYSAIEWDGKIYKAGQLVKTIKTLPLFYGSIVKFFLYGDHDGEVYATGGEVQIAMEPQALYDEIKTVPIAKLDRTVAEKAVKKYVEDEMARLPDRLSVTWPEGDELLPNEIRPAGTPIGALRIEILNKKGETMQKLPGTSHGGSKKLLVELKVILHSSSGNKEIISHISQHGGKWPYWFKKMENIHKLGNYTLKLQVVLNESNADTYAGRPLPSKAIKFSVKEGKPEKFSFGLLDPPFRVGVPFNIPVEFQDEFGHTSQLSTDIQPIFEASGLTLHYDEITKGPNCVIRGVTAKGPVNSCQGKVSINFNLKVILPGLKEDSQILKIRLLPGPPRRLKVKPDSEILVIENGTAFPFQVEVLDESDNITAQPKLIVHCKFSGAPNLPIYVVDCSSSGTSILSGPAIQVQNIKKDQTLKAKIEIPSCKDVAPVEKTIKLLPSSHVARLQIFSVEGQKAIQIKHQDEVNWIAGDVMHNLIFQMYDEGEREIHITSALSEKIKVNWTPEINKEHLLQGLLPDVQVPTSVKDMRYCQVSFQDDHVSLESAFTVRPLPDEPKHLKCELKGGKTVQMGQELQGEIVITVTDQYGNQIQAFSPSSLSALGIAGIGLDSSHLKTTFQENTQSINVKGIRFIPGPPGNKDLCFTWREFSDFIRVQLVSGPPAKLLLVDWPELKESIPVINGRELQNPLIVQLCDQWDNPAPVPQVKISLVKANNLKLTPSNQQHKTDERGRANFGVFSVLAPRGEHNMQVKAIYNKNTIEGPIIKLMILPDPEKPIRLNVKYDKDASFLAGGIFTDFMITVISEDDSIIKNINPARISMKMWKLANSGNRPPANAEIFSCNKIKDNDKEDGCFYFRDKAVPNKVGTYCIQFGFTMDKTNILNSEQIIVDVLPNQPVKLVPEIQPATPAVSNVRSVASRTLVKDLYLHITDDYNNHTGVDLVGTVMATIKGSNEEDDIPLFNGKIRTLEFPFVKGSAEITSLVLAENSPGRDSTEYFIVFEPRLPALSRTLESYILPFMFYNDVKKQQQMAALTKEKDQLSKSITVYRTLFDTSKQLLDEMKCQVEEAKLKEAQLRNELKKHNIDISTTQQVPHIEALLKRKLSEQEELKKKPRRSCTLPNYTKGSGDVLGKIAHLAQIEDDRAAMVISWHLASDMDCVVTLTTDAARRIYDETQGRQQVLPLDSIYKKTLPDWKRPLPHYRNGKLYFKPIGDPVFARDLLTFPDNVEHCETVFGMLLGDTIILDNLDAANHYRKEVVKITHCPTLLTRDGDRIRSNGKFGGLQNKAPPMDKLRGMVFGAPVPKQCLILGEQIDLLQQYRTAVCRLGSVNEDLNGQLKYLHTPDMKRKKQELDEHEKNLKLIEQKLGMTPTRKCNDSLPHPMTDCPVPPKRIRREAARQNRIITKTDV", "length": 2000, "header": "tr|F6RF21-1|F6RF21_BOVIN Isoform 1 of Structural maintenance of chromosomes flexible hinge domain-containing protein 1 OS=Bos taurus OX=9913 GN=SMCHD1 PE=3 SV=3 CANONICAL=F6RF21-1" }, "locus": { "chromosome": "24", "start_pos": 37053536, "end_pos": 36929125, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000003904.8", "url": "https://www.ensembl.org/id/ENSBTAT00000003904.8" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000003904.7", "url": "https://www.ensembl.org/id/ENSBTAP00000003904.7" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [], "orthologs": [], "go_annotation": { "categories": [ { "name": "Biological Process", "total": 6, "go_terms": [ { "name": "nose development", "id": "GO:0043584", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0043584", "evidence": [ { "database": "UniProtKB", "id": "F6RF21", "url": "https://www.uniprot.org/uniprotkb/F6RF21" } ], "pmid": "" }, { "name": "negative regulation of double-strand break repair via homologous recombination", "id": "GO:2000042", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:2000042", "evidence": [ { "database": "UniProtKB", "id": "F6RF21", "url": "https://www.uniprot.org/uniprotkb/F6RF21" } ], "pmid": "" }, { "name": "positive regulation of double-strand break repair via nonhomologous end joining", "id": "GO:2001034", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:2001034", "evidence": [ { "database": "UniProtKB", "id": "F6RF21", "url": "https://www.uniprot.org/uniprotkb/F6RF21" } ], "pmid": "" }, { "name": "double-strand break repair", "id": "GO:0006302", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006302", "evidence": [ { "database": "UniProtKB", "id": "F6RF21", "url": "https://www.uniprot.org/uniprotkb/F6RF21" } ], "pmid": "" }, { "name": "dosage compensation by inactivation of X chromosome", "id": "GO:0009048", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0009048", "evidence": [ { "database": "UniProtKB", "id": "F6RF21", "url": "https://www.uniprot.org/uniprotkb/F6RF21" } ], "pmid": "" }, { "name": "chromosome organization", "id": "GO:0051276", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0051276", "evidence": [ { "database": "UniProtKB", "id": "F6RF21", "url": "https://www.uniprot.org/uniprotkb/F6RF21" } ], "pmid": "" } ] }, { "name": "Molecular Function", "total": 5, "go_terms": [ { "name": "DNA binding", "id": "GO:0003677", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003677", "evidence": [ { "database": "UniProtKB", "id": "F6RF21", "url": "https://www.uniprot.org/uniprotkb/F6RF21" } ], "pmid": "" }, { "name": "ATP binding", "id": "GO:0005524", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005524", "evidence": [ { "database": "UniProtKB", "id": "F6RF21", "url": "https://www.uniprot.org/uniprotkb/F6RF21" } ], "pmid": "" }, { "name": "protein homodimerization activity", "id": "GO:0042803", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0042803", "evidence": [ { "database": "UniProtKB", "id": "F6RF21", "url": "https://www.uniprot.org/uniprotkb/F6RF21" } ], "pmid": "" }, { "name": "ATP hydrolysis activity", "id": "GO:0016887", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016887", "evidence": [ { "database": "UniProtKB", "id": "F6RF21", "url": "https://www.uniprot.org/uniprotkb/F6RF21" } ], "pmid": "" }, { "name": "hydrolase activity", "id": "GO:0016787", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016787", "evidence": [ { "database": "UniProtKB", "id": "F6RF21", "url": "https://www.uniprot.org/uniprotkb/F6RF21" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 4, "go_terms": [ { "name": "nuclear body", "id": "GO:0016604", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016604", "evidence": [ { "database": "UniProtKB", "id": "F6RF21", "url": "https://www.uniprot.org/uniprotkb/F6RF21" } ], "pmid": "" }, { "name": "site of double-strand break", "id": "GO:0035861", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0035861", "evidence": [ { "database": "UniProtKB", "id": "F6RF21", "url": "https://www.uniprot.org/uniprotkb/F6RF21" } ], "pmid": "" }, { "name": "chromosome, telomeric region", "id": "GO:0000781", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000781", "evidence": [ { "database": "UniProtKB", "id": "F6RF21", "url": "https://www.uniprot.org/uniprotkb/F6RF21" } ], "pmid": "" }, { "name": "Barr body", "id": "GO:0001740", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0001740", "evidence": [ { "database": "UniProtKB", "id": "F6RF21", "url": "https://www.uniprot.org/uniprotkb/F6RF21" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 1094, "end_pos": 1096, "annotation": "n_glycosylation_sequon" }, { "start_pos": 1527, "end_pos": 1529, "annotation": "n_glycosylation_sequon" }, { "start_pos": 1713, "end_pos": 1715, "annotation": "n_glycosylation_sequon" }, { "start_pos": 1967, "end_pos": 1969, "annotation": "n_glycosylation_sequon" }, { "start_pos": 784, "end_pos": 786, "annotation": "n_glycosylation_sequon" }, { "start_pos": 794, "end_pos": 796, "annotation": "n_glycosylation_sequon" }, { "start_pos": 943, "end_pos": 945, "annotation": "n_glycosylation_sequon" }, { "start_pos": 959, "end_pos": 961, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [ { "id": "13065", "name": "", "equation": "ATP + H2O = ADP + phosphate + H(+)", "summary": "", "cellular_location": "", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [ "A0AAA9S5G9-1", "F1MWZ4-1", "A0AAA9SX42-1", "A0AAA9RXI8-1", "A0AAF6DLT1-1", "A6QLE5-1", "F1MSG2-1", "F6QYF9-1", "A0A3Q1MR04-1", "Q05B79-1", "E1BDN4-1", "A0AAA9U2H6-1", "A0AAA9TGZ3-1", "A4K436-1", "Q5E9H5-1", "A0A3Q1LTL4-1", "A6QLJ0-1", "A0A3Q1LSH0-1", "Q3SZ54-1", "A0AAF6Z0U5-1", "F1N079-1", "F6R6W2-1", "A0A3Q1MR43-1", "A0AAA9TT64-1", "Q0V8H6-1", "A0AAF6Z733-1", "Q2KJI7-1", "P09487-1", "P19120-1", "Q0IIK5-1", "A0AAF6YVB0-1", "Q2KIZ8-1", "P63258-1", "A1A4H6-1", "A7YSY2-1", "A0A3Q1LG16-1", "A0AAA9RUK3-1", "Q1RMT1-1", "G3X757-1", "F1MN01-1", "A0AAA9TT27-1", "A0ABI0NX25-1", "F1MB25-1", "F1MEM4-1", "A0A3Q1M0A4-1", "A0A3Q1MU57-1", "A5D7C1-1", "A0AAA9SPF3-1", "A0A3Q1M155-1", "E1BAN8-1", "A0A3Q1MS44-1", "F1MSD2-1", "O18956-1", "Q76LV2-1", "A4FUD9-1", "A5PJA1-1", "A6QQR4-1", "Q32LC7-1", "Q3ZBT1-1", "Q3ZC07-1", "Q5W5U4-1", "E1B9N7-1", "G3N268-1", "E1BKM5-1", "P35071-1", "P60712-1", "P62739-1", "P68138-1", "Q0V8B7-1", "Q0VD48-1", "Q17R09-1", "Q29S22-1", "Q2NKY8-1", "Q2TBU9-1", "Q3B7N1-1", "Q0VCX2-1", "Q28141-1", "Q2NL22-1", "Q3T147-1", "Q3ZBH9-1", "Q3ZBV2-1", "Q3ZC91-1", "Q5E9B5-1", "Q5E9N5-1", "Q1LZ78-1", "E1BH89-1", "F1MNU7-1", "A0ABI0NSA6-1", "F1N533-1", "Q2NL08-1", "E1BF68-1", "F1MW45-1", "F1N272-1", "Q2TBP1-1", "Q3SZ40-1", "Q3SZ65-1", "A0AAA9RRF7-1", "A0ABI0P467-1", "A5PJI5-1", "A0AAA9T674-1", "Q95M18-1", "Q3ZCH0-1", "F1MMS0-1", "E1BH78-1", "A0ABI0P3F2-1", "A0AAF6DLQ5-1", "G3MYF0-1", "A0A3Q1LQN7-1", "A0ABI0NXS3-1", "A0A3Q1M7R9-1", "A0A3Q1LT80-1", "Q9TTA5-1", "Q3ZBH0-1", "Q2HJF8-1", "Q2NKZ1-1", "Q2T9X2-1", "Q32L40-1", "A7Z019-1", "F6QHI8-1", "E1BDM8-1", "E1BNG3-1", "E1BP01-1", "F1MRW7-1", "A0A3Q1LV49-1", "F1MWM0-1", "Q3MHL7-1", "Q3T0K2-1", "Q5E9M9-1", "Q3ZCI9-1", "F1MYC6-1", "F1MUT6-1", "A0A3Q1M493-1", "A0A3Q1LXD0-1", "F1N155-1", "E1BII7-1", "E1BPG1-1", "F1MMK3-1", "F1MSI6-1", "F1N1A2-1", "A0A3Q1NMG4-1", "A0AAA9STQ6-1", "A0AAA9T2L7-1", "F1MMD5-1", "A0A3Q1LQC3-1", "A0AAA9T8W7-1", "E1B887-1", "F1MLB2-1", "E1BPX4-1", "F1N2W9-1", "E1BB03-1", "E1BMP7-1", "A0JND9-1", "E1BAS6-1", "A0AAA9RXM7-1", "Q59HJ6-1", "Q2KJ94-1", "A0A3Q1MDD8-1", "G3X6Y8-1", "A0AAF6Z0E4-1", "G3MZH7-1", "F1MKC7-1", "A0AAA9S7V9-1", "A0AAF6YME1-1", "F1MFR1-1", "Q3T084-1", "E1B7X9-1", "A0ABI0P204-1" ], "evidence": [ { "id": "13065", "database": "Rhea", "url": "https://www.rhea-db.org/rhea/13065" } ] } ], "reaction_participants": [], "reaction_enzymes": [ { "uniprot_ac": "A0A3Q1LG16", 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} ] }, { "ec_number": "2.3.2.27", "activity": "", "evidence": [ { "id": "A0A3Q1LV49", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1LV49" } ] } ] }, { "uniprot_ac": "A0A3Q1LXD0", "gene_name": "DDX49", "activity": [ { "ec_number": "3.6.4.13", "activity": "ATP + H2O = ADP + phosphate + H(+).", "evidence": [ { "id": "A0A3Q1LXD0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1LXD0" } ] }, { "ec_number": "3.6.4.13", "activity": "", "evidence": [ { "id": "A0A3Q1LXD0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1LXD0" } ] } ] }, { "uniprot_ac": "A0A3Q1M0A4", "gene_name": "ATP13A5", "activity": [ { "ec_number": "7.2.2.-", "activity": "", "evidence": [ { "id": "A0A3Q1M0A4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1M0A4" } ] } ] }, { "uniprot_ac": "A0A3Q1M155", "gene_name": "DDX5", "activity": [ { "ec_number": "3.6.4.13", "activity": "ATP + H2O = ADP + phosphate + H(+).", 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"https://www.uniprot.org/uniprotkb/E1B9N7" } ] } ] }, { "uniprot_ac": "E1BAN8", "gene_name": "INO80", "activity": [ { "ec_number": "3.6.4.-", "activity": "", "evidence": [ { "id": "E1BAN8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BAN8" } ] } ] }, { "uniprot_ac": "E1BAS6", "gene_name": "SETX", "activity": [ { "ec_number": "3.6.4.12", "activity": "ATP + H2O = ADP + phosphate + H(+).", "evidence": [ { "id": "E1BAS6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BAS6" } ] }, { "ec_number": "3.6.4.13", "activity": "ATP + H2O = ADP + phosphate + H(+).", "evidence": [ { "id": "E1BAS6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BAS6" } ] }, { "ec_number": "3.6.4.12", "activity": "", "evidence": [ { "id": "E1BAS6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BAS6" } ] }, { "ec_number": "3.6.4.13", "activity": "", "evidence": [ { "id": "E1BAS6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BAS6" } ] } ] }, { "uniprot_ac": "E1BB03", "gene_name": "ZRANB3", "activity": [ { "ec_number": "3.1.-.-", "activity": "", "evidence": [ { "id": "E1BB03", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BB03" } ] }, { "ec_number": "3.6.4.-", "activity": "", "evidence": [ { "id": "E1BB03", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BB03" } ] }, { "ec_number": "5.6.2.-", "activity": "", "evidence": [ { "id": "E1BB03", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BB03" } ] } ] }, { "uniprot_ac": "E1BDM8", "gene_name": "DDX6", "activity": [ { "ec_number": "3.6.4.13", "activity": "ATP + H2O = ADP + phosphate + H(+).", "evidence": [ { "id": "E1BDM8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BDM8" } ] }, { "ec_number": "3.6.4.13", "activity": "", "evidence": [ { "id": "E1BDM8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BDM8" } ] } ] }, { "uniprot_ac": "E1BDN4", "gene_name": "DHX35", "activity": [ { "ec_number": "3.6.4.13", "activity": "ATP + H2O = ADP + phosphate + H(+).", "evidence": [ { "id": "E1BDN4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BDN4" } ] }, { "ec_number": "3.6.4.13", "activity": "", "evidence": [ { "id": "E1BDN4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BDN4" } ] } ] }, { "uniprot_ac": "E1BF68", "gene_name": "DHX16", "activity": [ { "ec_number": "3.6.4.13", "activity": "ATP + H2O = ADP + phosphate + H(+).", "evidence": [ { "id": "E1BF68", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BF68" } ] }, { "ec_number": "3.6.4.13", "activity": "", "evidence": [ { "id": "E1BF68", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BF68" } ] } ] }, { "uniprot_ac": "E1BH78", "gene_name": "SNRNP200", "activity": [ { "ec_number": "3.6.4.13", "activity": "ATP + H2O = ADP + phosphate + H(+).", "evidence": [ { "id": "E1BH78", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BH78" } ] }, { "ec_number": "3.6.4.13", "activity": "", "evidence": [ { "id": "E1BH78", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BH78" } ] } ] }, { "uniprot_ac": "E1BH89", "gene_name": "MCM6", "activity": [ { "ec_number": "3.6.4.12", "activity": "ATP + H2O = ADP + phosphate + H(+).", "evidence": [ { "id": "E1BH89", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BH89" } ] }, { "ec_number": "3.6.4.12", "activity": "", "evidence": [ { "id": "E1BH89", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BH89" } ] } ] }, { "uniprot_ac": "E1BII7", "gene_name": "DDX43", "activity": [ { "ec_number": "3.6.4.13", "activity": "ATP + H2O = ADP + phosphate + H(+).", "evidence": [ { "id": "E1BII7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BII7" } ] }, { "ec_number": "3.6.4.13", "activity": "", "evidence": [ { "id": "E1BII7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BII7" } ] } ] }, { "uniprot_ac": "E1BKM5", "gene_name": "RECQL5", "activity": [ { "ec_number": "5.6.2.4", "activity": "ATP + H2O = ADP + phosphate + H(+).", "evidence": [ { "id": "E1BKM5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BKM5" } ] }, { "ec_number": "5.6.2.4", "activity": "", "evidence": [ { "id": "E1BKM5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BKM5" } ] } ] }, { "uniprot_ac": "E1BMP7", "gene_name": "DNA2", "activity": [ { "ec_number": "3.1.-.-", "activity": "", "evidence": [ { "id": "E1BMP7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BMP7" } ] }, { "ec_number": "5.6.2.3", "activity": "Couples ATP hydrolysis with the unwinding of duplex DNA at the replication fork by translocating in the 5'-3' direction.", "evidence": [ { "id": "E1BMP7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BMP7" } ] } ] }, { "uniprot_ac": "E1BNG3", "gene_name": "ascc3", "activity": [ { "ec_number": "5.6.2.4", "activity": "ATP + H2O = ADP + phosphate + H(+).", "evidence": [ { "id": "E1BNG3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BNG3" } ] }, { "ec_number": "5.6.2.4", "activity": "", "evidence": [ { "id": "E1BNG3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BNG3" } ] } ] }, { "uniprot_ac": "E1BP01", "gene_name": "MYO3A", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "E1BP01", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BP01" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "E1BP01", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BP01" } ] } ] }, { "uniprot_ac": "E1BPG1", "gene_name": "ZGRF1", "activity": [ { "ec_number": "5.6.2.3", "activity": "Couples ATP hydrolysis with the unwinding of duplex DNA at the replication fork by translocating in the 5'-3' direction.", "evidence": [ { "id": "E1BPG1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BPG1" } ] }, { "ec_number": "5.6.2.3", "activity": "", "evidence": [ { "id": "E1BPG1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BPG1" } ] } ] }, { "uniprot_ac": "E1BPX4", "gene_name": "MCM8", "activity": [ { "ec_number": "5.6.2.4", "activity": "ATP + H2O = ADP + phosphate + H(+).", "evidence": [ { "id": "E1BPX4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BPX4" } ] }, { "ec_number": "5.6.2.4", "activity": "", "evidence": [ { "id": "E1BPX4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BPX4" } ] } ] }, { "uniprot_ac": "F1MB25", "gene_name": "ENTPD1", "activity": [ { "ec_number": "3.6.1.5", "activity": "a 2'-deoxyribonucleoside 5'-triphosphate + 2 H2O = a 2'-deoxyribonucleoside 5'-phosphate + 2 phosphate + 2 H(+).", "evidence": [ { "id": "F1MB25", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MB25" } ] }, { "ec_number": "3.6.1.5", "activity": "", "evidence": [ { "id": "F1MB25", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MB25" } ] } ] }, { "uniprot_ac": "F1MEM4", "gene_name": "DHX8", "activity": [ { "ec_number": "3.6.4.13", "activity": "ATP + H2O = ADP + phosphate + H(+).", "evidence": [ { "id": "F1MEM4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MEM4" } ] }, { "ec_number": "3.6.4.13", "activity": "", "evidence": [ { "id": "F1MEM4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MEM4" } ] } ] }, { "uniprot_ac": "F1MFR1", "gene_name": "HFM1", "activity": [ { "ec_number": "5.6.2.4", "activity": "ATP + H2O = ADP + phosphate + H(+).", "evidence": [ { "id": "F1MFR1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MFR1" } ] }, { "ec_number": "5.6.2.4", "activity": "", "evidence": [ { "id": "F1MFR1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MFR1" } ] } ] }, { "uniprot_ac": "F1MKC7", "gene_name": "HELZ", "activity": [ { "ec_number": "3.6.4.13", "activity": "ATP + H2O = ADP + phosphate + H(+).", "evidence": [ { "id": "F1MKC7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MKC7" } ] }, { "ec_number": "3.6.4.13", "activity": "", "evidence": [ { "id": "F1MKC7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MKC7" } ] } ] }, { "uniprot_ac": "F1MLB2", "gene_name": "CHD8", "activity": [ { "ec_number": "3.6.4.-", "activity": "", "evidence": [ { "id": "F1MLB2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MLB2" } ] } ] }, { "uniprot_ac": "F1MMD5", "gene_name": "XRCC6", "activity": [ { "ec_number": "4.2.99.18", "activity": "2'-deoxyribonucleotide-(2'-deoxyribose 5'-phosphate)-2'-deoxyribonucleotide-DNA = a 3'-end 2'-deoxyribonucleotide-(2,3-dehydro-2,3-deoxyribose 5'-phosphate)-DNA + a 5'-end 5'-phospho-2'-deoxyribonucleoside-DNA + H(+).", "evidence": [ { "id": "F1MMD5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MMD5" } ] }, { "ec_number": "5.6.2.4", "activity": "ATP + H2O = ADP + phosphate + H(+).", "evidence": [ { "id": "F1MMD5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MMD5" } ] }, { "ec_number": "5.6.2.4", "activity": "", "evidence": [ { "id": "F1MMD5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MMD5" } ] }, { "ec_number": "4.2.99.18", "activity": "", "evidence": [ { "id": "F1MMD5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MMD5" } ] }, { "ec_number": "3.6.4.12", "activity": "ATP + H2O = ADP + phosphate + H(+).", "evidence": [ { "id": "F1MMD5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MMD5" } ] }, { "ec_number": "3.6.4.12", "activity": "", "evidence": [ { "id": "F1MMD5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MMD5" } ] } ] }, { "uniprot_ac": "F1MMK3", "gene_name": "DDX50", "activity": [ { "ec_number": "3.6.4.13", "activity": "ATP + H2O = ADP + phosphate + H(+).", "evidence": [ { "id": "F1MMK3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MMK3" } ] }, { "ec_number": "3.6.4.13", "activity": "", "evidence": [ { "id": "F1MMK3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MMK3" } ] } ] }, { "uniprot_ac": "F1MMS0", "gene_name": "BRIP1", "activity": [ { "ec_number": "5.6.2.3", "activity": "Couples ATP hydrolysis with the unwinding of duplex DNA at the replication fork by translocating in the 5'-3' direction.", "evidence": [ { "id": "F1MMS0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MMS0" } ] }, { "ec_number": "5.6.2.3", "activity": "", "evidence": [ { "id": "F1MMS0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MMS0" } ] } ] }, { "uniprot_ac": "F1MN01", "gene_name": "CFTR", "activity": [ { "ec_number": "5.6.1.6", "activity": "ATP + H2O + closed Cl(-) channel = ADP + phosphate + open Cl(-) channel.", "evidence": [ { "id": "F1MN01", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MN01" } ] }, { "ec_number": "5.6.1.6", "activity": "", "evidence": [ { "id": "F1MN01", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MN01" } ] } ] }, { "uniprot_ac": "F1MNU7", "gene_name": "YTHDC2", "activity": [ { "ec_number": "3.6.4.13", "activity": "ATP + H2O = ADP + phosphate + H(+).", "evidence": [ { "id": "F1MNU7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MNU7" } ] }, { "ec_number": "3.6.4.13", "activity": "", "evidence": [ { "id": "F1MNU7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MNU7" } ] } ] }, { "uniprot_ac": "F1MRW7", "gene_name": "DDX20", "activity": [ { "ec_number": "3.6.1.15", "activity": "a ribonucleoside 5'-triphosphate + H2O = a ribonucleoside 5'-diphosphate + phosphate + H(+).", "evidence": [ { "id": "F1MRW7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MRW7" } ] }, { "ec_number": "3.6.4.13", "activity": "ATP + H2O = ADP + phosphate + H(+).", "evidence": [ { "id": "F1MRW7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MRW7" } ] }, { "ec_number": "3.6.4.13", "activity": "", "evidence": [ { "id": "F1MRW7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MRW7" } ] }, { "ec_number": "3.6.1.15", "activity": "", "evidence": [ { "id": "F1MRW7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MRW7" } ] } ] }, { "uniprot_ac": "F1MSD2", "gene_name": "RUVBL2", "activity": [ { "ec_number": "3.6.4.12", "activity": "ATP + H2O = ADP + phosphate + H(+).", "evidence": [ { "id": "F1MSD2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MSD2" } ] }, { "ec_number": "3.6.4.12", "activity": "", "evidence": [ { "id": "F1MSD2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MSD2" } ] } ] }, { "uniprot_ac": "F1MSG2", "gene_name": "FBH1", "activity": [ { "ec_number": "5.6.2.4", "activity": "ATP + H2O = ADP + phosphate + H(+).", "evidence": [ { "id": "F1MSG2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MSG2" } ] }, { "ec_number": "5.6.2.4", "activity": "", "evidence": [ { "id": "F1MSG2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MSG2" } ] } ] }, { "uniprot_ac": "F1MSI6", "gene_name": "DDX25", "activity": [ { "ec_number": "3.6.4.13", "activity": "ATP + H2O = ADP + phosphate + H(+).", "evidence": [ { "id": "F1MSI6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MSI6" } ] }, { "ec_number": "3.6.4.13", "activity": "", "evidence": [ { "id": "F1MSI6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MSI6" } ] } ] }, { "uniprot_ac": "F1MUT6", "gene_name": "DDX19B", "activity": [ { "ec_number": "3.6.4.13", "activity": "ATP + H2O = ADP + phosphate + H(+).", "evidence": [ { "id": "F1MUT6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MUT6" } ] }, { "ec_number": "3.6.4.13", "activity": "", "evidence": [ { "id": "F1MUT6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MUT6" } ] } ] }, { "uniprot_ac": "F1MW45", "gene_name": "DDX55", "activity": [ { "ec_number": "3.6.4.13", "activity": "ATP + H2O = ADP + phosphate + H(+).", "evidence": [ { "id": "F1MW45", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MW45" } ] }, { "ec_number": "3.6.4.13", "activity": "", "evidence": [ { "id": "F1MW45", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MW45" } ] } ] }, { "uniprot_ac": "F1MWM0", "gene_name": "ABCA4", "activity": [ { "ec_number": "7.6.2.1", "activity": "ATP + H2O + phospholipidSide 1 = ADP + phosphate + phospholipidSide 2.", "evidence": [ { "id": "F1MWM0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MWM0" } ] }, { "ec_number": "7.6.2.1", "activity": "", "evidence": [ { "id": "F1MWM0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MWM0" } ] } ] }, { "uniprot_ac": "F1MWZ4", "gene_name": "DHX33", "activity": [ { "ec_number": "3.6.4.13", "activity": "ATP + H2O = ADP + phosphate + H(+).", "evidence": [ { "id": "F1MWZ4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MWZ4" } ] }, { "ec_number": "3.6.4.13", "activity": "", "evidence": [ { "id": "F1MWZ4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MWZ4" } ] } ] }, { "uniprot_ac": "F1MYC6", "gene_name": "DDX4", "activity": [ { "ec_number": "3.6.4.13", "activity": "ATP + H2O = ADP + phosphate + H(+).", "evidence": [ { "id": "F1MYC6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MYC6" } ] }, { "ec_number": "3.6.4.13", "activity": "", "evidence": [ { "id": "F1MYC6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MYC6" } ] } ] }, { "uniprot_ac": "F1N079", "gene_name": "RTEL1", "activity": [ { "ec_number": "5.6.2.-", "activity": "", "evidence": [ { "id": "F1N079", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1N079" } ] } ] }, { "uniprot_ac": "F1N155", "gene_name": "CLPX", "activity": [ { "ec_number": "3.6.4.10", "activity": "ATP + H2O = ADP + phosphate + H(+).", "evidence": [ { "id": "F1N155", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1N155" } ] }, { "ec_number": "3.6.4.10", "activity": "", "evidence": [ { "id": "F1N155", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1N155" } ] } ] }, { "uniprot_ac": "F1N1A2", "gene_name": "DHX57", "activity": [ { "ec_number": "3.6.4.13", "activity": "ATP + H2O = ADP + phosphate + H(+).", "evidence": [ { "id": "F1N1A2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1N1A2" } ] }, { "ec_number": "3.6.4.13", "activity": "", "evidence": [ { "id": "F1N1A2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1N1A2" } ] } ] }, { "uniprot_ac": "F1N272", "gene_name": "ATP13A4", "activity": [ { "ec_number": "7.2.2.-", "activity": "", "evidence": [ { "id": "F1N272", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1N272" } ] } ] }, { "uniprot_ac": "F1N2W9", "gene_name": "MCM9", "activity": [ { "ec_number": "5.6.2.4", "activity": "ATP + H2O = ADP + phosphate + H(+).", "evidence": [ { "id": "F1N2W9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1N2W9" } ] }, { "ec_number": "5.6.2.4", "activity": "", "evidence": [ { "id": "F1N2W9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1N2W9" } ] } ] }, { "uniprot_ac": "F1N533", "gene_name": "DDX18", "activity": [ { "ec_number": "3.6.4.13", "activity": "ATP + H2O = ADP + phosphate + H(+).", "evidence": [ { "id": "F1N533", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1N533" } ] }, { "ec_number": "3.6.4.13", "activity": "", "evidence": [ { "id": "F1N533", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1N533" } ] } ] }, { "uniprot_ac": "F6QHI8", "gene_name": "DDX21", "activity": [ { "ec_number": "3.6.4.13", "activity": "ATP + H2O = ADP + phosphate + H(+).", "evidence": [ { "id": "F6QHI8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F6QHI8" } ] }, { "ec_number": "3.6.4.13", "activity": "", "evidence": [ { "id": "F6QHI8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F6QHI8" } ] } ] }, { "uniprot_ac": "F6QYF9", "gene_name": "DDX41", "activity": [ { "ec_number": "3.6.4.13", "activity": "ATP + H2O = ADP + phosphate + H(+).", "evidence": [ { "id": "F6QYF9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F6QYF9" } ] }, { "ec_number": "3.6.4.13", "activity": "", "evidence": [ { "id": "F6QYF9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F6QYF9" } ] } ] }, { 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2'-deoxyribonucleoside 5'-phosphate + 2 phosphate + 2 H(+).", "evidence": [ { "id": "G3MZH7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3MZH7" } ] }, { "ec_number": "3.6.1.5", "activity": "", "evidence": [ { "id": "G3MZH7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3MZH7" } ] } ] }, { "uniprot_ac": "G3N268", "gene_name": "DHX58", "activity": [ { "ec_number": "3.6.4.13", "activity": "ATP + H2O = ADP + phosphate + H(+).", "evidence": [ { "id": "G3N268", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3N268" } ] }, { "ec_number": "3.6.4.13", "activity": "", "evidence": [ { "id": "G3N268", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3N268" } ] } ] }, { "uniprot_ac": "G3X6Y8", "gene_name": "ENTPD8", "activity": [ { "ec_number": "3.6.1.5", "activity": "a 2'-deoxyribonucleoside 5'-triphosphate + 2 H2O = a 2'-deoxyribonucleoside 5'-phosphate + 2 phosphate + 2 H(+).", "evidence": [ { "id": "G3X6Y8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3X6Y8" } ] }, { "ec_number": "3.6.1.5", "activity": "", "evidence": [ { "id": "G3X6Y8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3X6Y8" } ] } ] }, { "uniprot_ac": "G3X757", "gene_name": "VCP", "activity": [ { "ec_number": "3.6.4.6", "activity": "ATP + H2O = ADP + phosphate + H(+).", "evidence": [ { "id": "G3X757", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3X757" } ] }, { "ec_number": "3.6.4.6", "activity": "", "evidence": [ { "id": "G3X757", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3X757" } ] } ] }, { "uniprot_ac": "O18956", "gene_name": "ENTPD1", "activity": [ { "ec_number": "3.6.1.5", "activity": "a 2'-deoxyribonucleoside 5'-triphosphate + 2 H2O = a 2'-deoxyribonucleoside 5'-phosphate + 2 phosphate + 2 H(+).", "evidence": [ { "id": "O18956", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/O18956" } ] }, { "ec_number": 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"activity": [ { "ec_number": "3.6.4.-", "activity": "", "evidence": [ { "id": "P63258", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P63258" } ] } ] }, { "uniprot_ac": "P68138", "gene_name": "ACTA1", "activity": [ { "ec_number": "3.6.4.-", "activity": "", "evidence": [ { "id": "P68138", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P68138" } ] } ] }, { "uniprot_ac": "Q05B79", "gene_name": "DHX36", "activity": [ { "ec_number": "3.6.4.12", "activity": "ATP + H2O = ADP + phosphate + H(+).", "evidence": [ { "id": "Q05B79", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q05B79" } ] }, { "ec_number": "3.6.4.13", "activity": "ATP + H2O = ADP + phosphate + H(+).", "evidence": [ { "id": "Q05B79", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q05B79" } ] }, { "ec_number": "3.6.4.13", "activity": "", "evidence": [ { "id": "Q05B79", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q05B79" } ] }, { "ec_number": "3.6.4.12", "activity": "", "evidence": [ { "id": "Q05B79", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q05B79" } ] } ] }, { "uniprot_ac": "Q0IIK5", "gene_name": "DDX1", "activity": [ { "ec_number": "3.6.4.13", "activity": "ATP + H2O = ADP + phosphate + H(+).", "evidence": [ { "id": "Q0IIK5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q0IIK5" } ] }, { "ec_number": "3.6.4.13", "activity": "", "evidence": [ { "id": "Q0IIK5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q0IIK5" } ] } ] }, { "uniprot_ac": "Q0V8B7", "gene_name": "MCM5", "activity": [ { "ec_number": "3.6.4.12", "activity": "ATP + H2O = ADP + phosphate + H(+).", "evidence": [ { "id": "Q0V8B7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q0V8B7" } ] }, { "ec_number": "3.6.4.12", "activity": "", "evidence": [ { "id": "Q0V8B7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q0V8B7" } ] } ] }, { 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{ "ec_number": "3.6.4.13", "activity": "ATP + H2O = ADP + phosphate + H(+).", "evidence": [ { "id": "Q28141", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q28141" } ] }, { "ec_number": "3.6.4.13", "activity": "", "evidence": [ { "id": "Q28141", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q28141" } ] } ] }, { "uniprot_ac": "Q29S22", "gene_name": "DDX47", "activity": [ { "ec_number": "3.6.4.13", "activity": "ATP + H2O = ADP + phosphate + H(+).", "evidence": [ { "id": "Q29S22", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q29S22" } ] }, { "ec_number": "3.6.4.13", "activity": "", "evidence": [ { "id": "Q29S22", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q29S22" } ] } ] }, { "uniprot_ac": "Q2HJF8", "gene_name": "RHOT1", "activity": [ { "ec_number": "3.6.5.-", "activity": "", "evidence": [ { "id": "Q2HJF8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q2HJF8" } ] } ] }, { "uniprot_ac": "Q2KIZ8", "gene_name": "MCM6", "activity": [ { "ec_number": "3.6.4.12", "activity": "ATP + H2O = ADP + phosphate + H(+).", "evidence": [ { "id": "Q2KIZ8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q2KIZ8" } ] }, { "ec_number": "3.6.4.12", "activity": "", "evidence": [ { "id": "Q2KIZ8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q2KIZ8" } ] } ] }, { "uniprot_ac": "Q2KJ94", "gene_name": "RAD51", "activity": [ { "ec_number": "3.6.4.-", "activity": "", "evidence": [ { "id": "Q2KJ94", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q2KJ94" } ] } ] }, { "uniprot_ac": "Q2KJI7", "gene_name": "AFG3L2", "activity": [ { "ec_number": "3.4.24.-", "activity": "", "evidence": [ { "id": "Q2KJI7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q2KJI7" } ] }, { "ec_number": "3.6.-.-", "activity": "", "evidence": [ { "id": "Q2KJI7", "database": "UniProtKB", "url": 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"http://www.pantherdb.org/panther/family.do?clsAccession=PTHR10265", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR10265:SF44", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR10265:SF44", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF02234", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF02234", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "A0AAA9SLS2", "url": "https://www.uniprot.org/uniprotkb/A0AAA9SLS2", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0AAA9SLS2-1", "url": "https://www.uniprot.org/uniprotkb/A0AAA9SLS2-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "F1N786", "url": "https://www.uniprot.org/uniprotkb/F1N786", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "F1N786-1", "url": "https://www.uniprot.org/uniprotkb/F1N786-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MERLVARRTFPMIARTSACRSLFGPVDHEELGRELQMRLAELSAEDQRRWDYNFQLDMPLRGPGRLQWTEVDSDSVPAFYRETVQVGRCRLLLAPRPRPDGAVNNPPPGPPADESVDGLGEAPASPSSGPAVVPAQAAAPAPQEGSELEAVPPPRSQEPQAEPPHSGISGRPAPGTAAAATSAAAAATTAAAGGAAIKKLSGPLISDFFAKRKRPAPEAKASNEVPGGCAAPGAAPAVGSAEQTPRKRLR", "length": 250, "header": "tr|F1N786-1|F1N786_BOVIN Isoform 1 of Cyclin-dependent kinase inhibitor 1C OS=Bos taurus OX=9913 GN=CDKN1C PE=3 SV=1 CANONICAL=F1N786-1" }, "isoforms": [ { "isoform_ac": "A0AAA9SLS2-1", "url": "https://www.uniprot.org/uniprotkb/A0AAA9SLS2/entry", "sequence": { "sequence": "MERLVARRTFPMIARTSACRSLFGPVDHEELGRELQMRLAELSAEDQRRWDYNFQLDMPLRGPGRLQWTEVDSDSVPAFYRETVQTSSPSARDPRPKPRRRTRFLGDAPRLAPLQPSARLSKPRASGCDEASCSKSPDGARWAVDRRGALGLGWDRPCSSNPRQLPRAAFGFVFKV", "length": 176, "header": "tr|A0AAA9SLS2-1|F1N786_BOVIN Computationally mapped isoform of Cyclin-dependent kinase inhibitor 1C OS=Bos taurus OX=9913 GN=CDKN1C PE=3 SV=2 CANONICAL=F1N786-1" }, "locus": { "chromosome": "29", "start_pos": 48730360, "end_pos": 48728830, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000118450.2", "url": "https://www.ensembl.org/id/ENSBTAT00000118450.2" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000084891.2", "url": "https://www.ensembl.org/id/ENSBTAP00000084891.2" } ] } }, { "isoform_ac": "F1N786-1", "url": "https://www.uniprot.org/uniprotkb/F1N786/entry", "sequence": { "sequence": "MERLVARRTFPMIARTSACRSLFGPVDHEELGRELQMRLAELSAEDQRRWDYNFQLDMPLRGPGRLQWTEVDSDSVPAFYRETVQVGRCRLLLAPRPRPDGAVNNPPPGPPADESVDGLGEAPASPSSGPAVVPAQAAAPAPQEGSELEAVPPPRSQEPQAEPPHSGISGRPAPGTAAAATSAAAAATTAAAGGAAIKKLSGPLISDFFAKRKRPAPEAKASNEVPGGCAAPGAAPAVGSAEQTPRKRLR", "length": 250, "header": "tr|F1N786-1|F1N786_BOVIN Isoform 1 of Cyclin-dependent kinase inhibitor 1C OS=Bos taurus OX=9913 GN=CDKN1C PE=3 SV=1 CANONICAL=F1N786-1" }, "locus": { "chromosome": "29", "start_pos": 48730112, "end_pos": 48728830, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000044159.5", "url": "https://www.ensembl.org/id/ENSBTAT00000044159.5" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000041672.2", "url": "https://www.ensembl.org/id/ENSBTAP00000041672.2" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [], "orthologs": [], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 2, "go_terms": [ { "name": "nucleus", "id": "GO:0005634", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005634", "evidence": [ { "database": "UniProtKB", "id": "F1N786", "url": "https://www.uniprot.org/uniprotkb/F1N786" } ], "pmid": "" }, { "name": "cytoplasm", "id": "GO:0005737", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005737", "evidence": [ { "database": "UniProtKB", "id": "F1N786", "url": "https://www.uniprot.org/uniprotkb/F1N786" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 4, "go_terms": [ { "name": "regulation of cell cycle", "id": "GO:0051726", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0051726", "evidence": [ { "database": "UniProtKB", "id": "F1N786", "url": "https://www.uniprot.org/uniprotkb/F1N786" } ], "pmid": "" }, { "name": "negative regulation of DNA-templated transcription", "id": "GO:0045892", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0045892", "evidence": [ { "database": "UniProtKB", "id": "F1N786", "url": "https://www.uniprot.org/uniprotkb/F1N786" } ], "pmid": "" }, { "name": "negative regulation of epithelial cell proliferation", "id": "GO:0050680", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0050680", "evidence": [ { "database": "UniProtKB", "id": "F1N786", "url": "https://www.uniprot.org/uniprotkb/F1N786" } ], "pmid": "" }, { "name": "positive regulation of transforming growth factor beta receptor signaling pathway", "id": "GO:0030511", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030511", "evidence": [ { "database": "UniProtKB", "id": "F1N786", "url": "https://www.uniprot.org/uniprotkb/F1N786" } ], "pmid": "" } ] }, { "name": "Molecular Function", "total": 2, "go_terms": [ { "name": "cyclin-dependent protein serine/threonine kinase inhibitor activity", "id": "GO:0004861", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0004861", "evidence": [ { "database": "UniProtKB", "id": "F1N786", "url": "https://www.uniprot.org/uniprotkb/F1N786" } ], "pmid": "" }, { "name": "protein-containing complex binding", "id": "GO:0044877", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0044877", "evidence": [ { "database": "UniProtKB", "id": "F1N786", "url": "https://www.uniprot.org/uniprotkb/F1N786" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "F1N786", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1N786" }, { "id": "PF02234", "database": "Pfam", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF02234" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "Cyclin-dependent kinase inhibitor", "eco_id": "ECO_0000259", "start_pos": 21, "end_pos": 71, "start_aa": "Ser", "end_aa": "Val", "glycosite_overlap": [] } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ], "tool_support": { "graph_view": "yes" } }, { "uniprot_canonical_ac": "F6Q3F4-1", "uniprot_ac": "F6Q3F4", "uniprot_id": "F6Q3F4_BOVIN", "mass": { "chemical_mass": 56155.0, "monoisotopic_mass": 56155.0 }, "refseq": {}, "gene_names": [ { "name": "ZNF277", "type": "recommended", "evidence": [ { "id": "F6Q3F4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F6Q3F4" } ] } ], "protein_names": [ { "name": "Zinc finger protein 277", "type": "synonym", "evidence": [ { "id": "F6Q3F4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F6Q3F4/entry#names_and_taxonomy" } ] } ], "function": [], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Bos taurus", "taxid": 9913, "evidence": [ { "database": "UniProtKB", "id": "F6Q3F4", "url": "https://www.uniprot.org/uniprotkb/F6Q3F4" } ], "common_name": "Bovine", "glygen_name": "Bovine", "reference_species": "Bos taurus [9913]" } ], "gene": [ { "name": "ZNF277", "url": "https://www.uniprot.org/uniprotkb/F6Q3F4", "locus": { "chromosome": "4", "start_pos": 55985103, "end_pos": 56120770, "strand": "+", "evidence": [ { "database": "Ensembl Gene", "id": "ENSBTAG00000013050", "url": "https://www.ensembl.org/id/ENSBTAG00000013050" } ] } } ], "crossref": [ { "id": "F6Q3F4", "url": "https://alphafold.ebi.ac.uk/entry/F6Q3F4", "database": "AlphaFoldDB", "categories": [] }, { "id": "ENSBTAG00000013050", "url": "https://bgee.org/?page=gene&gene_id=ENSBTAG00000013050", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "IPR013087", "url": "https://www.ebi.ac.uk/interpro/entry/IPR013087", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR036236", "url": "https://www.ebi.ac.uk/interpro/entry/IPR036236", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR040048", "url": "https://www.ebi.ac.uk/interpro/entry/IPR040048", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR041661", "url": "https://www.ebi.ac.uk/interpro/entry/IPR041661", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "WDKPEFF", "url": "https://omabrowser.org/oma/group/WDKPEFF/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "F6Q3F4", "url": "https://www.orthodb.org/?gene=F6Q3F4", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR13267", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR13267", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR13267:SF3", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR13267:SF3", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF12756", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF12756", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "A0AAA9SYN3", "url": "https://www.uniprot.org/uniprotkb/A0AAA9SYN3", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0AAA9SYN3-1", "url": "https://www.uniprot.org/uniprotkb/A0AAA9SYN3-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "F6Q3F4", "url": "https://www.uniprot.org/uniprotkb/F6Q3F4", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "F6Q3F4-1", "url": "https://www.uniprot.org/uniprotkb/F6Q3F4-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MFSLRDCCLPLHPGKSLQPLPSLSRVMAAPKTQGAATQGEDSDGNRGGAGGVNYEDTKDYILEPLSLPESPGGTTSLEGSPSVPCIFCEEHFPVVEQDKLLKHMIIEHKIVIADVKLVADFRRYILYWRKRFTEQPITDFCSVIRINCTAPSEEQDNYFLLCDVLPEDRILREELQKQRLKEILEQQQQERNDNSFRGICMFCNEEFLGNRSILLNHMAREHAFNIGLPDNIVNCNEFLCTLQKKLDNLQCLYCEKTFRDKNTLKDHMRKKQHRRINPKNREYDRFYVINYLELGKSWEEVQLEDDRELLEHQEDDWSDWEEHPVSAVCLFCEKQAETIEKLCVHMEDAHEFDLLKIKSELGLNFYQQVKLVNFIRRQIHQCRCYGCQEKFRSKADLRTHMEEAKHTALLPEKQIWDQPQYYFPTYENDTLLCTLSDSESDLTAQEQNGNIAIISEDTSKLHALKQSSILNQLLLHESLKN", "length": 481, "header": "tr|F6Q3F4-1|F6Q3F4_BOVIN Isoform 1 of Zinc finger protein 277 OS=Bos taurus OX=9913 GN=ZNF277 PE=3 SV=2 CANONICAL=F6Q3F4-1" }, "isoforms": [ { "isoform_ac": "A0AAA9SYN3-1", "url": "https://www.uniprot.org/uniprotkb/A0AAA9SYN3/entry", "sequence": { "sequence": "MAAPKTQGAATQGEDSDGNRGGAGGVNYEDTKDYILEPLSLPESPGGTTSLEGSPSVPCIFCEEHFPVVEQDKLLKHMIIEHKIVIADVKLVADFRRYILYWRKRFTEQPITDFCSVIRINCTAPSEEQDNYFLLCDVLPEDRILREELQKQRLKEILEQQQQERNDNSFRGICMFCNEEFLGNRSILLNHMAREHAFNIGLPDNIVNCNEFLCTLQKKLDNLQCLYCEKTFRDKNTLKDHMRKKQHRRINPKNREYDRFYVINYLVRLSFHNLKFDCMSTN", "length": 282, "header": "tr|A0AAA9SYN3-1|F6Q3F4_BOVIN Computationally mapped isoform of Zinc finger protein 277 OS=Bos taurus OX=9913 GN=ZNF277 PE=3 SV=1 CANONICAL=F6Q3F4-1" }, "locus": { "chromosome": "4", "start_pos": 56119403, "end_pos": 56000983, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000129061.1", "url": "https://www.ensembl.org/id/ENSBTAT00000129061.1" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000089206.1", "url": "https://www.ensembl.org/id/ENSBTAP00000089206.1" } ] } }, { "isoform_ac": "F6Q3F4-1", "url": "https://www.uniprot.org/uniprotkb/F6Q3F4/entry", "sequence": { "sequence": "MFSLRDCCLPLHPGKSLQPLPSLSRVMAAPKTQGAATQGEDSDGNRGGAGGVNYEDTKDYILEPLSLPESPGGTTSLEGSPSVPCIFCEEHFPVVEQDKLLKHMIIEHKIVIADVKLVADFRRYILYWRKRFTEQPITDFCSVIRINCTAPSEEQDNYFLLCDVLPEDRILREELQKQRLKEILEQQQQERNDNSFRGICMFCNEEFLGNRSILLNHMAREHAFNIGLPDNIVNCNEFLCTLQKKLDNLQCLYCEKTFRDKNTLKDHMRKKQHRRINPKNREYDRFYVINYLELGKSWEEVQLEDDRELLEHQEDDWSDWEEHPVSAVCLFCEKQAETIEKLCVHMEDAHEFDLLKIKSELGLNFYQQVKLVNFIRRQIHQCRCYGCQEKFRSKADLRTHMEEAKHTALLPEKQIWDQPQYYFPTYENDTLLCTLSDSESDLTAQEQNGNIAIISEDTSKLHALKQSSILNQLLLHESLKN", "length": 481, "header": "tr|F6Q3F4-1|F6Q3F4_BOVIN Isoform 1 of Zinc finger protein 277 OS=Bos taurus OX=9913 GN=ZNF277 PE=3 SV=2 CANONICAL=F6Q3F4-1" }, "locus": { "chromosome": "4", "start_pos": 56120486, "end_pos": 55985275, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000017348.7", "url": "https://www.ensembl.org/id/ENSBTAT00000017348.7" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000017348.6", "url": "https://www.ensembl.org/id/ENSBTAP00000017348.6" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [], "orthologs": [ { "uniprot_canonical_ac": "A0A8C2MWJ7-1", "protein_name": "Zinc finger protein 277 isoform X1", "gene_name": "Znf277", "tax_id": 10029, "organism": "Cricetulus griseus", "sequence": { "sequence": "MAATEARGLGADQREDAAGVRGGVGTMDLEDSKDCILEPLSLPESPGGSTASEGPPSVPCLFCEEHFPVAEQDKLLKHMIIEHKIVIADVKLVADFQRYILYWRKRFTEQPITDFCSVIRINSTAPFEEQDNYFLLCDVLPEDRILREELQKQRLKEILDQQQRERNDTSFHGVCMFCSEEFRGNRSVLLNHMAREHAFNIGLPDNIVNCTEFLCTLQKKLDNLQCLYCEKTFRDKNTLKDHMRKKQHRRINPKNRDYDRFYVINYLELGKSWEEVQLEDDRELLGLPEDDWSDWQEYPVCAVCLFCEKQEETIDKLYVHMKDTHEFDLLRIKSELRLNFYQQVKLVNFIRRQVHQCRCYGCHVKFKSKTDLRAHMEEAKHTSLLPDRKTWDQLEYYFPTYENDTLLCTLSDSESDLTAQEHNENVPVISEDTSKLCALKRSSVLNQLLLQERLEN", "length": 456 }, "evidence": [ { "id": "F6Q3F4", "url": "https://omabrowser.org/oma/group/F6Q3F4/", "database": "OMA" } ], "glygen_name": "Hamster", "common_name": "Chinese hamster" }, { "uniprot_canonical_ac": "A0A8V0XAA2-1", "protein_name": "Zinc finger protein 277", "gene_name": "ZNF277", "tax_id": 9031, "organism": "Gallus gallus", "sequence": { "sequence": "MAAARGEGGPAARGECILEPLSLPESPASPDGVATVESSPSVPCIFCEECYVLAEQNQLLKHMIIEHKLVIADVKLVADFKRYVLYWKKRFAEQPVTDFCSVIRTNSEAPLEEQDNYFLLCDVLPEDRLLREQLQQKRLREILEQQQQERYDTSFHSMCMFCDQEFTGNRSVLLNHMAREHAFNIGLPDNIVNCYEFLAVLQEKLDNLQCLYCEKVFRDKNTLKDHMRKKQHRRINAKNKEYDRFYIINYLEFGKSWEEVQSEDDRELLDNLEEDWSDWEEHPVCAVCLFCEQQADTTEKLHLHMQKSHGFDFLKIKSELGLNFYQQVKLVNFIRREIHHRRCYNCQEKFQSKGGLISHMEETKHITFLPARSTWDQPQYYFPTYENDTLLCTLSDSEDLIPEDQSEDVPVVSEDISSLKALKQSSILNQLLCEENSSHDKS", "length": 442 }, "evidence": [ { "id": "F6Q3F4", "url": "https://omabrowser.org/oma/group/F6Q3F4/", "database": "OMA" } ], "glygen_name": "Chicken", "common_name": "Chicken" }, { "uniprot_canonical_ac": "Q54Q44-1", "protein_name": "C2H2-type zinc finger-containing protein", "gene_name": "", "tax_id": 44689, "organism": "Dictyostelium discoideum", "sequence": { "sequence": "MQDWSKWPTVEPLKSSLTFDFNNNNNNNNNIQIPTIITPATTTTTTTTTTTSTTATTTGSISNLNINQSDSEDLSASDAESTSSVVSSNTNNTGVKYPCLLCSHFEFESRTILEHIFNQHKFVIADVNQITNLVGYLEHWKKQFVGKPLTEFTTVVQTQTSKSEPVTNYYLLSDILPQDQDIRRKLQTGQLNSILEQQHSERINPNFTCICPMCPATFKGDRSSVTTHLVEQHNFNIGLSDNLVNLKELLEILKEKCDEMQCLYCEKIFKSQSVLKLHMKKKKHNRLNPTNTTYDKYYLLNYLEPGKNWEDLKKDHGDNDDDDNKYINNIDIMKQAQNENNGNHQISHWDDWTEGSENEIEDTAVCLFCETHFDNSDCTFEHMRNVHNFDFDKKRKSWNLDYYESIKLLNFIRRCVSEMICCYCGDNSFKDKETFFSHLHINQHEHCGVIQENPVWKDAQYLFPTYENDNILTNFEEFDESENQQYLEEELEYQSNLIDEMQQNRDDILKKMNESNITF", "length": 519 }, "evidence": [ { "id": "F6Q3F4", "url": "https://omabrowser.org/oma/group/F6Q3F4/", "database": "OMA" } ], "glygen_name": "Cellular slime mold", "common_name": "Social amoeba" }, { "uniprot_canonical_ac": "Q9NRM2-1", "protein_name": "Zinc finger protein 277", "gene_name": "ZNF277", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MAASKTQGAVARMQEDRDGSCSTVGGVGYGDSKDCILEPLSLPESPGGTTTLEGSPSVPCIFCEEHFPVAEQDKLLKHMIIEHKIVIADVKLVADFQRYILYWRKRFTEQPITDFCSVIRINSTAPFEEQENYFLLCDVLPEDRILREELQKQRLREILEQQQQERNDTNFHGVCMFCNEEFLGNRSVILNHMAREHAFNIGLPDNIVNCNEFLCTLQKKLDNLQCLYCEKTFRDKNTLKDHMRKKQHRKINPKNREYDRFYVINYLELGKSWEEVQLEDDRELLDHQEDDWSDWEEHPASAVCLFCEKQAETIEKLYVHMEDAHEFDLLKIKSELGLNFYQQVKLVNFIRRQVHQCRCYGCHVKFKSKADLRTHMEETKHTSLLPDRKTWDQLEYYFPTYENDTLLCTLSDSESDLTAQEQNENVPIISEDTSKLYALKQSSILNQLLL", "length": 450 }, "evidence": [ { "id": "F6Q3F4", "url": "https://omabrowser.org/oma/group/F6Q3F4/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "Q9W1V7-1", "protein_name": "Zinc finger protein 277", "gene_name": "", "tax_id": 7227, "organism": "Drosophila melanogaster", "sequence": { "sequence": "MEHEVAVSGGDSSLEEITGSSKLKPSKNTAIKCLKCDKVYIFPSDKDDCLAHLYMEHRLVIADVEDIALLEDYLQYWEKEFHTHEFEQYCTTMFLDQLPDGKYAKNEKYYLLCDILPQDYELRRRLKEKRLSEALERHQFELTDRTFSKECLFCRAIIKGLRADYLDHLFDKHFLLVGKPEKLVYVDELLDHLEENLNRLMCLYCEKIFRDRPTLKEHMRKKGHKRINPNRREYDKYFLINYNRVPTAPTPRKQHLQKRRRETASVSTVADPETGSVDFDKHFARPDSDGEHDSDWSDWAADGEPSSIKCLFCHHLGDNFTALKKHMHEVHRLDFEKATSSLNFYQRVKVVNYLRRQMCLLRCVTCDLQFDEEELLVEHMAQESHHGIGDKESWDKPEFFFPYIENDGLLCVLDDSGGDDPDVDTVRIISEDSLAQINKDAERLSLENFKLL", "length": 452 }, "evidence": [ { "id": "F6Q3F4", "url": "https://omabrowser.org/oma/group/F6Q3F4/", "database": "OMA" } ], "glygen_name": "Fruit fly", "common_name": "Fruit fly" } ], "go_annotation": { "categories": [ { "name": "Molecular Function", "total": 1, "go_terms": [ { "name": "zinc ion binding", "id": "GO:0008270", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008270", "evidence": [ { "database": "UniProtKB", "id": "F6Q3F4", "url": "https://www.uniprot.org/uniprotkb/F6Q3F4" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 147, "end_pos": 149, "annotation": "n_glycosylation_sequon" }, { "start_pos": 210, "end_pos": 212, "annotation": "n_glycosylation_sequon" }, { "start_pos": 428, "end_pos": 430, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "F6Q3F4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F6Q3F4" }, { "id": "PS50157", "database": "PROSITE", "url": "https://prosite.expasy.org/PS50157" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "C2H2-type", "eco_id": "ECO_0000259", "start_pos": 249, "end_pos": 278, "start_aa": "Leu", "end_aa": "Pro", "glycosite_overlap": [] } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" }, { "name": "homologset.oma", "label": "OMA Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 147, "end_pos": 149 }, { "start_pos": 210, "end_pos": 212 }, { "start_pos": 428, "end_pos": 430 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ], "tool_support": { "graph_view": "yes" } }, { "uniprot_canonical_ac": "F6Q7K4-1", "uniprot_ac": "F6Q7K4", "uniprot_id": "F6Q7K4_BOVIN", "mass": { "chemical_mass": 10214.0, "monoisotopic_mass": 10214.0 }, "refseq": { "ac": "XP_005228004", "name": "HIG1 domain family member 1A, mitochondrial", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_005228004" }, "gene_names": [ { "name": "LOC786015", "type": "recommended", "evidence": [ { "id": "F6Q7K4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F6Q7K4" } ] }, { "name": "LOC786015", "type": "synonym", "evidence": [ { 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"locus": {} } ], "crossref": [ { "id": "F6Q7K4", "url": "https://alphafold.ebi.ac.uk/entry/F6Q7K4", "database": "AlphaFoldDB", "categories": [] }, { "id": "786015", "url": "https://www.ncbi.nlm.nih.gov/gene/786015", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR007667", "url": "https://www.ebi.ac.uk/interpro/entry/IPR007667", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR050355", "url": "https://www.ebi.ac.uk/interpro/entry/IPR050355", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "bta:786015", "url": "https://www.genome.jp/dbget-bin/www_bget?bta:786015", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "PTHR12297", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR12297", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR12297:SF5", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR12297:SF5", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF04588", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF04588", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "XP_005228004", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_005228004", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "F6Q7K4", "url": "https://www.uniprot.org/uniprotkb/F6Q7K4", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "F6Q7K4-1", "url": "https://www.uniprot.org/uniprotkb/F6Q7K4-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MSSDTDISLSSYDEDQGSKLIRKAREAPFVPVGMAGFAAIVAYGLYRLKSRGHTKMSVHLIHMRVAAQGFVVGAMTLGMGYSLYQEFWGKPKP", "length": 93, "header": "tr|F6Q7K4-1|F6Q7K4_BOVIN Isoform 1 of HIG1 domain-containing protein OS=Bos taurus OX=9913 GN=LOC786015 PE=4 SV=2 CANONICAL=F6Q7K4-1" }, "isoforms": [ { "isoform_ac": "F6Q7K4-1", "url": "https://www.uniprot.org/uniprotkb/F6Q7K4/entry", "sequence": { "sequence": "MSSDTDISLSSYDEDQGSKLIRKAREAPFVPVGMAGFAAIVAYGLYRLKSRGHTKMSVHLIHMRVAAQGFVVGAMTLGMGYSLYQEFWGKPKP", "length": 93, "header": "tr|F6Q7K4-1|F6Q7K4_BOVIN Isoform 1 of HIG1 domain-containing protein OS=Bos taurus OX=9913 GN=LOC786015 PE=4 SV=2 CANONICAL=F6Q7K4-1" }, "locus": { "chromosome": "X", "start_pos": 66781935, "end_pos": 66781657, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000044991.5", "url": "https://www.ensembl.org/id/ENSBTAT00000044991.5" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000042422.4", "url": "https://www.ensembl.org/id/ENSBTAP00000042422.4" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [ { "id": "bta:786015", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?bta:786015", "resource": "KEGG Pathway" } ], "orthologs": [], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 1, "go_terms": [ { 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{ "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": 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TLRs (Toll-like receptors) control host immune response against pathogens through recognition of molecular patterns specific to microorganisms. TLR9 is a nucleotide-sensing TLR which is activated by unmethylated cytidine-phosphate-guanosine (CpG) dinucleotides. Acts via MYD88 and TRAF6, leading to NF-kappa-B activation, cytokine secretion and the inflammatory response. Also acts via ADCY7, leading to cyclic di-AMP (c-di-AMP) synthesis and activation of the NLRP3 inflammasome. Plays a role in defense against systemic mouse cytomegalovirus infection. Controls lymphocyte response to Helicobacter infection. Upon CpG stimulation, induces B-cell proliferation, activation, survival and antibody production.", "evidence": [ { "database": "UniProtKB", "id": "A0A3Q1MK24", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1MK24#function" }, { "database": "UniProtKB", "id": "ARBA00094474", "url": "https://www.uniprot.org/uniprotkb/ARBA00094474#function" }, { "database": "UniProtKB", "id": "A0AAA9RUI2", "url": "https://www.uniprot.org/uniprotkb/A0AAA9RUI2#function" }, { "database": "UniProtKB", "id": "F6QR22", "url": "https://www.uniprot.org/uniprotkb/F6QR22#function" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Bos taurus", "taxid": 9913, "evidence": [ { "database": "UniProtKB", "id": "F6QR22", "url": "https://www.uniprot.org/uniprotkb/F6QR22" } ], "common_name": "Bovine", "glygen_name": "Bovine", "reference_species": "Bos taurus [9913]" } ], "gene": [ { "name": "TLR7", "url": 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"database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF01582", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF01582", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF13855", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF13855", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF18837", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF18837", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "R-BTA-1679131", "url": "https://www.reactome.org/PathwayBrowser/#R-BTA-1679131", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "R-BTA-168181", "url": "https://www.reactome.org/PathwayBrowser/#R-BTA-168181", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "R-BTA-5686938", "url": "https://www.reactome.org/PathwayBrowser/#R-BTA-5686938", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { 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"length": 1054, "header": "tr|A0A3Q1MK24-1|A0A3Q1MK24_BOVIN Computationally mapped isoform of Toll-like receptor 9 OS=Bos taurus OX=9913 GN=TLR7 PE=3 SV=1 CANONICAL=F6QR22-1" }, "locus": { "chromosome": "X", "start_pos": 130786228, "end_pos": 130769578, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000079344.2", "url": "https://www.ensembl.org/id/ENSBTAT00000079344.2" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000071792.1", "url": "https://www.ensembl.org/id/ENSBTAP00000071792.1" } ] } }, { "isoform_ac": "A0AAA9RUI2-1", "url": "https://www.uniprot.org/uniprotkb/A0AAA9RUI2/entry", "sequence": { "sequence": "MWTLKRQFPILFNMILISGLLGARWFPKTLPCDVTLDAPNTHVIVDCTDKHLTEIPGGIPANATNLTLTINHIAGISPASFHRLDHLVEIDFRCNCVPVRLGPKDNVCTKRLQIKPNSFSKLTYLKSLYLDGNQLLEIPQDLPPSLQLLSLEANNIFLIMKENLTELANLEILYLGQNCYYRNPCNVSFTIEKDAFLNMRNLKLLSLKDNNISAVPTVLPSSLTELYLYNNIITKIQEDDFNNLSQLQVLDLSGNCPRCYNVPFPCTPCENNSPLQIDPNAFDALTELQVLRLHSNSLQHVPQRWFKNINKLKELDLSQNFLAKEIGDAKFLHLLHNLVNLDLSFNYDLQVYHAVINLSDAFSSLKKLKVLRIKGYVFKELNSLNLFPLHNLPNLEVLDLGTNFIKIANLSIFNQFKTLKFIDLSVNKISPSGDSPEGGFCSNRRTSVEGHGPQVLETLHYFRYDEYARSCRSKSKEPPSFLPLNEDCYMYGQTLDLSRNNIFFIKPSDFQHLSFLKCLNLSGNSISQTLNGSEFQPLVELKYLDFSNNRLDLLYSTAFEELHNLEVLDISSNSHYFQSEGITHMLNFTKNLKVLRKLMMNYNDIATSTSRTMESESLQILEFRGNHLDILWRDGDNRYLKFFKNLLNLEELDISENSLSFLPLGVFDSMPPNLKTLSLAKNGLKSFSWERLQSLKNLETLDLSFNQLKTVPERLSNCSRSLKKLILKNNQIRCLTKYFLQGAFQLRHLDLSSNKIQVIQKTSFPENVLNNLNILFLHHNRFLCNCDAVWFVWWVNHTEVTIPYLATDVTCMGPGAHKGQSVVSLDLYTCELDLTNFILFSLSISAVLSLMMITIANHLYFWDVWYSYHFCKAKIKGYRRLISPNSCYDAFIVYDTKDPAVTEWVLDELVAKLEDPREKCFNLCLEERDWLPGQPVLENLSQSIQLSKKTVFVMTDKYAKTENFKIAFYLSHQRLMDEKVDVIILIFLEKPLQKSKFLQLRKRLCGSSVLEWPTNPQAHPYFWQCLKNALATDNHVTYSQVFKETA", "length": 1046, "header": "tr|A0AAA9RUI2-1|F6QR22_BOVIN Computationally mapped isoform of Toll-like receptor 9 OS=Bos taurus OX=9913 GN=TLR7 PE=3 SV=1 CANONICAL=F6QR22-1" }, "locus": { "chromosome": "X", "start_pos": 130772715, "end_pos": 130769578, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000096664.1", "url": "https://www.ensembl.org/id/ENSBTAT00000096664.1" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000077958.1", "url": "https://www.ensembl.org/id/ENSBTAP00000077958.1" } ] } }, { "isoform_ac": "F6QR22-1", "url": "https://www.uniprot.org/uniprotkb/F6QR22/entry", "sequence": { "sequence": "MLKAKYVFPMWTLKRQFPILFNMILISGLLGARWFPKTLPCDVTLDAPNTHVIVDCTDKHLTEIPGGIPANATNLTLTINHIAGISPASFHRLDHLVEIDFRCNCVPVRLGPKDNVCTKRLQIKPNSFSKLTYLKSLYLDGNQLLEIPQDLPPSLQLLSLEANNIFLIMKENLTELANLEILYLGQNCYYRNPCNVSFTIEKDAFLNMRNLKLLSLKDNNISAVPTVLPSSLTELYLYNNIITKIQEDDFNNLSQLQVLDLSGNCPRCYNVPFPCTPCENNSPLQIDPNAFDALTELQVLRLHSNSLQHVPQRWFKNINKLKELDLSQNFLAKEIGDAKFLHLLHNLVNLDLSFNYDLQVYHAVINLSDAFSSLKKLKVLRIKGYVFKELNSLNLFPLHNLPNLEVLDLGTNFIKIANLSIFNQFKTLKFIDLSVNKISPSGDSPEGGFCSNRRTSVEGHGPQVLETLHYFRYDEYARSCRSKSKEPPSFLPLNEDCYMYGQTLDLSRNNIFFIKPSDFQHLSFLKCLNLSGNSISQTLNGSEFQPLVELKYLDFSNNRLDLLYSTAFEELHNLEVLDISSNSHYFQSEGITHMLNFTKNLKVLRKLMMNYNDIATSTSRTMESESLQILEFRGNHLDILWRDGDNRYLKFFKNLLNLEELDISENSLSFLPLGVFDSMPPNLKTLSLAKNGLKSFSWERLQSLKNLETLDLSFNQLKTVPERLSNCSRSLKKLILKNNQIRCLTKYFLQGAFQLRHLDLSSNKIQVIQKTSFPENVLNNLNILFLHHNRFLCNCDAVWFVWWVNHTEVTIPYLATDVTCMGPGAHKGQSVVSLDLYTCELDLTNFILFSLSISAVLSLMMITIANHLYFWDVWYSYHFCKAKIKGYRRLISPNSCYDAFIVYDTKDPAVTEWVLDELVAKLEDPREKCFNLCLEERDWLPGQPVLENLSQSIQLSKKTVFVMTDKYAKTENFKIAFYLSHQRLMDEKVDVIILIFLEKPLQKSKFLQLRKRLCGSSVLEWPTNPQAHPYFWQCLKNALATDNHVTYSQVFKETA", "length": 1055, "header": "tr|F6QR22-1|F6QR22_BOVIN Isoform 1 of Toll-like receptor 9 OS=Bos taurus OX=9913 GN=TLR7 PE=3 SV=1 CANONICAL=F6QR22-1" }, "locus": { "chromosome": "X", "start_pos": 130772935, "end_pos": 130769578, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000029895.6", "url": "https://www.ensembl.org/id/ENSBTAT00000029895.6" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000029890.5", "url": "https://www.ensembl.org/id/ENSBTAP00000029890.5" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [ { "id": "R-BTA-1679131", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-BTA-1679131", "resource": "Reactome", "description": "Trafficking and processing of endosomal TLR" }, { "id": "R-BTA-168181", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-BTA-168181", "resource": "Reactome", "description": "Toll Like Receptor 7/8 (TLR7/8) Cascade" }, { "id": "R-BTA-5686938", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-BTA-5686938", "resource": "Reactome", "description": "Regulation of TLR by endogenous ligand" } ], "orthologs": [], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 6, "go_terms": [ { "name": "endosome", "id": "GO:0005768", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005768", "evidence": [ { "database": "UniProtKB", "id": "F6QR22", "url": "https://www.uniprot.org/uniprotkb/F6QR22" } ], "pmid": "" }, { "name": "lysosome", "id": "GO:0005764", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005764", "evidence": [ { "database": "UniProtKB", "id": "F6QR22", "url": "https://www.uniprot.org/uniprotkb/F6QR22" } ], "pmid": "" }, { "name": "endoplasmic reticulum membrane", "id": "GO:0005789", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005789", "evidence": [ { "database": "UniProtKB", "id": "F6QR22", "url": "https://www.uniprot.org/uniprotkb/F6QR22" } ], "pmid": "" }, { "name": "phagocytic vesicle", "id": "GO:0045335", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0045335", "evidence": [ { "database": "UniProtKB", "id": "F6QR22", "url": "https://www.uniprot.org/uniprotkb/F6QR22" } ], "pmid": "" }, { "name": "plasma membrane", "id": "GO:0005886", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005886", "evidence": [ { "database": "UniProtKB", "id": "F6QR22", "url": "https://www.uniprot.org/uniprotkb/F6QR22" } ], "pmid": "" }, { "name": "receptor complex", "id": "GO:0043235", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0043235", "evidence": [ { "database": "UniProtKB", "id": "F6QR22", "url": "https://www.uniprot.org/uniprotkb/F6QR22" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 19, "go_terms": [ { "name": "inflammatory response", "id": "GO:0006954", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006954", "evidence": [ { "database": "UniProtKB", "id": "F6QR22", "url": "https://www.uniprot.org/uniprotkb/F6QR22" } ], "pmid": "" }, { "name": "signal transduction", "id": "GO:0007165", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007165", "evidence": [ { "database": "UniProtKB", "id": "F6QR22", "url": "https://www.uniprot.org/uniprotkb/F6QR22" } ], "pmid": "" }, { "name": "innate immune response", "id": "GO:0045087", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0045087", "evidence": [ { "database": "UniProtKB", "id": "F6QR22", "url": "https://www.uniprot.org/uniprotkb/F6QR22" } ], "pmid": "" }, { "name": "activation of innate immune response", "id": "GO:0002218", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0002218", "evidence": [ { "database": "UniProtKB", "id": "F6QR22", "url": "https://www.uniprot.org/uniprotkb/F6QR22" } ], "pmid": "" }, { "name": "positive regulation of toll-like receptor 9 signaling pathway", "id": "GO:0034165", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0034165", "evidence": [ { "database": "UniProtKB", "id": "F6QR22", "url": "https://www.uniprot.org/uniprotkb/F6QR22" } ], "pmid": "" }, { 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"D3ZEU8-1", "protein_name": "Family with sequence similarity 76, member A", "gene_name": "Fam76a", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "STSTRTSERPLSTGEPAPEPAARLRPPALRSPRAGRRRQECRIAHPVVKCIYCRTEYQQESKTNTICKKCAQNVQLYGTPKPCQYCNIIAAFIGDKCQRCTNSEKKYGPPYSCEQCKQQCAFDRKDDRKKVDGKLLCWLCTLSYKRVLQKTREQRKHLSSSSRGSHQEKEQYSRLSGGSHYNSQKTLSTSSIQNEIPKKKSKFESITTNGDSFSPDLALDSPGTDHFVIIAQLKEEVATLKKMLHQKDQMILEKEKKITELKADFQYQESQTRAKMNQMEKTHKEVTEQLQAKNRELLKQAAALSKSKKSEKSGTITSP", "length": 319 }, "evidence": [ { "id": "F1N6L6", "url": "https://omabrowser.org/oma/group/F1N6L6/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "I3LLZ7-1", "protein_name": "Family with sequence similarity 76 member A", "gene_name": "FAM76A", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MAALYACTKCHQRFPFEALSQGQQLCKECRIAHPVVKCTYCRTEYQQESKTNTICKKCAQNVQLYGTPKPCQYCNIIAAFIGNKCQRCTNSEKKYGPPYSCEQCKQQCAFDRKDDRKKVDGKLLCWLCTLSYKRVLQKTKEQRKHLSSSSRTSHQEKEQYSRLSGGHYNSQKTLSTSSIQNEIPKKKSKFESITTNGDSFSPDLALDSPGTDHFVIIAQLKEEVATLKKMLHQKDQMILEKEKKITELKADFQYQESQMRAKMNQMEKTHKEVTEQLQAKNRELLKQAAALSKSKKSEKSGAITSP", "length": 306 }, "evidence": [ { "id": "F1N6L6", "url": "https://omabrowser.org/oma/group/F1N6L6/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "Q8TAV0-1", "protein_name": "Protein FAM76A", "gene_name": "FAM76A", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MAALYACTKCHQRFPFEALSQGQQLCKECRIAHPVVKCTYCRTEYQQESKTNTICKKCAQNVQLYGTPKPCQYCNIIAAFIGNKCQRCTNSEKKYGPPYSCEQCKQQCAFDRKDDRKKVDGKLLCWLCTLSYKRVLQKTKEQRKHLSSSSRAGHQEKEQYSRLSGGGHYNSQKTLSTSSIQNEIPKKKSKFESITTNGDSFSPDLALDSPGTDHFVIIAQLKEEVATLKKMLHQKDQMILEKEKKITELKADFQYQESQMRAKMNQMEKTHKEVTEQLQAKNRELLKQAAALSKSKKSEKSGAITSP", "length": 307 }, "evidence": [ { "id": "F1N6L6", "url": "https://omabrowser.org/oma/group/F1N6L6/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "Q922G2-1", "protein_name": "Protein FAM76A", "gene_name": "Fam76a", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MAALYACTKCHQRFPFEALSQGQQLCKECRIAHPVVKCTYCRTEYQQESKTNTICKKCAQNVQLYGTPKPCQYCNIIAAFIGNKCQRCTNSEKKYGPPYSCEQCKQQCAFDRKDDRKKVDGKLLCWLCTLSYKRVLQKTKEQRKHLSSSSRGSHQEKEQYSRLSGGSHYNSQKTLSTSSIQNEIPKKKSKFESITTNGDSFSPDLALDSPGTDHFVIIAQLKEEVATLKKMLHQKDQMILEKEKKITELKADFQYQESQTRAKMNQMEKTHKEVTEQLQAKNRELLKQAAALSKSKKSEKSGTITSP", "length": 307 }, "evidence": [ { "id": "F1N6L6", "url": "https://omabrowser.org/oma/group/F1N6L6/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" } ], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 2, "go_terms": [ { "name": "nucleoplasm", "id": "GO:0005654", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005654", "evidence": [ { "database": "UniProtKB", "id": "F1N6L6", "url": "https://www.uniprot.org/uniprotkb/F1N6L6" } ], "pmid": "" }, { "name": "nuclear speck", "id": "GO:0016607", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016607", "evidence": [ { "database": "UniProtKB", "id": "F1N6L6", "url": "https://www.uniprot.org/uniprotkb/F1N6L6" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [ { "pdb_id": "AF-F1N6L6-F1", "pdb_chain": "global", "start_pos": 1, "end_pos": 307, "overlap": "1.0", "method": "AlphaFold", "type": "alphafold", "resolution": -1.0, "url": "https://data.glygen.org/ln2downloads/pdb/current/AF-F1N6L6-F1.pdb", "url_external": "https://alphafold.ebi.ac.uk/entry/F1N6L6" } ], "lectin_list": [], "domain_list": [], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" }, { "name": "homologset.oma", "label": "OMA Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ], "tool_support": { "graph_view": "yes" } }, { "uniprot_canonical_ac": "F6R8Z4-1", "uniprot_ac": "F6R8Z4", "uniprot_id": "F6R8Z4_BOVIN", "mass": { "chemical_mass": 58822.0, "monoisotopic_mass": 58822.0 }, "refseq": {}, "gene_names": [], "protein_names": [ { "name": "TRAF interacting protein", "type": "synonym", "evidence": [ { "id": "F6R8Z4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F6R8Z4/entry#names_and_taxonomy" } ] } ], "function": [], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Bos taurus", "taxid": 9913, "evidence": [ { "database": "UniProtKB", "id": "F6R8Z4", "url": "https://www.uniprot.org/uniprotkb/F6R8Z4" } ], "common_name": "Bovine", "glygen_name": "Bovine", "reference_species": "Bos taurus [9913]" } ], "gene": [ { "name": "", "url": "https://www.uniprot.org/uniprotkb/F6R8Z4", "locus": {} } ], "crossref": [ { "id": "F6R8Z4", "url": "https://alphafold.ebi.ac.uk/entry/F6R8Z4", "database": "AlphaFoldDB", "categories": [] }, { "id": "cd16480", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd16480", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "IPR001841", "url": "https://www.ebi.ac.uk/interpro/entry/IPR001841", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR013083", "url": "https://www.ebi.ac.uk/interpro/entry/IPR013083", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR052639", "url": "https://www.ebi.ac.uk/interpro/entry/IPR052639", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "PTHR46569", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR46569", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR46569:SF1", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR46569:SF1", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF13639", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF13639", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "A0AAA9RWC0", "url": "https://www.uniprot.org/uniprotkb/A0AAA9RWC0", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0AAA9RWC0-1", "url": "https://www.uniprot.org/uniprotkb/A0AAA9RWC0-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "F6R8Z4", "url": "https://www.uniprot.org/uniprotkb/F6R8Z4", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "F6R8Z4-1", "url": "https://www.uniprot.org/uniprotkb/F6R8Z4-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MKPLPILSRKLRRGAKFEASEDAEARPPSWTRRRFLGYLGYSRPVIMPIRALCTICSDFFDHSRDVAAIHCGHTFHSHCLIQWFETAPSRTCPQCRIQVGKRTIINKLYFDLAPEEENVLDTEFLKNELDNTRALLSQKEKEKRDSQLIIDSLRDTLDERNATVESLQRALDKAEMLCSTLKKQMKYLEQQQDEAKQAREEARRLRSKMKNMERIELLLRSQRPEVEEMIRDMGVGQSAVEQLAVYCVSLKKEYENLKEARKASGELADKLKKDLLSSRSKLQTVCSELDQAKLELKSSQKDLQSADKEIASLKKKLTILQETLKLPPGDSETINRLVLESPAPMEMVSLKLRRPAFGDDIDLNATFNVDTPPTQPSSTQYGLAKRLFPKKAHSPVQDIPKKMPKGPRQESQLSLGGQRCLGEPDEELASAFPVFIRNAVLGQKQTKRVRAEPCRSTDAVRIGFDGLGGRTKFIQPTDTTMIRPLPVKPKPKARARQKLGARTAPTPSQATLDNFLWQ", "length": 518, "header": "tr|F6R8Z4-1|F6R8Z4_BOVIN Isoform 1 of TRAF interacting protein OS=Bos taurus OX=9913 GN= PE=4 SV=1 CANONICAL=F6R8Z4-1" }, "isoforms": [ { "isoform_ac": "A0AAA9RWC0-1", "url": "https://www.uniprot.org/uniprotkb/A0AAA9RWC0/entry", "sequence": { "sequence": "MPIRALCTICSDFFDHSRDVAAIHCGHTFHSHCLIQWFETAPSRTCPQCRIQVGKRTIINKLYFDLAPEEENVLDTEFLKLQTVCSELDQAKLELKSSQKDLQSADKEIASLKKKLTILQETLKLPPGDSETINRLVLESPAPMEMVSLKLRRPAFGDDIDLNATFNVDTPPTQPSSTQYGLAKRLFPKKAHSPVQDIPKKMPKGPRQESQLSLGGQRCLGEPDEELASAFPVFIRNAVLGQKQTKRVRAEPCRSTDAVRIGFDGLGGRTKFIQPVSLFCGVGLS", "length": 285, "header": "tr|A0AAA9RWC0-1|F6R8Z4_BOVIN Computationally mapped isoform of TRAF interacting protein OS=Bos taurus OX=9913 GN= PE=4 SV=1 CANONICAL=F6R8Z4-1" }, "locus": { "chromosome": "22", "start_pos": 50416246, "end_pos": 50399308, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000110196.1", "url": "https://www.ensembl.org/id/ENSBTAT00000110196.1" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000075414.1", "url": "https://www.ensembl.org/id/ENSBTAP00000075414.1" } ] } }, { "isoform_ac": "F6R8Z4-1", "url": "https://www.uniprot.org/uniprotkb/F6R8Z4/entry", "sequence": { "sequence": "MKPLPILSRKLRRGAKFEASEDAEARPPSWTRRRFLGYLGYSRPVIMPIRALCTICSDFFDHSRDVAAIHCGHTFHSHCLIQWFETAPSRTCPQCRIQVGKRTIINKLYFDLAPEEENVLDTEFLKNELDNTRALLSQKEKEKRDSQLIIDSLRDTLDERNATVESLQRALDKAEMLCSTLKKQMKYLEQQQDEAKQAREEARRLRSKMKNMERIELLLRSQRPEVEEMIRDMGVGQSAVEQLAVYCVSLKKEYENLKEARKASGELADKLKKDLLSSRSKLQTVCSELDQAKLELKSSQKDLQSADKEIASLKKKLTILQETLKLPPGDSETINRLVLESPAPMEMVSLKLRRPAFGDDIDLNATFNVDTPPTQPSSTQYGLAKRLFPKKAHSPVQDIPKKMPKGPRQESQLSLGGQRCLGEPDEELASAFPVFIRNAVLGQKQTKRVRAEPCRSTDAVRIGFDGLGGRTKFIQPTDTTMIRPLPVKPKPKARARQKLGARTAPTPSQATLDNFLWQ", "length": 518, "header": "tr|F6R8Z4-1|F6R8Z4_BOVIN Isoform 1 of TRAF interacting protein OS=Bos taurus OX=9913 GN= PE=4 SV=1 CANONICAL=F6R8Z4-1" }, "locus": { "chromosome": "22", "start_pos": 50416549, "end_pos": 50397010, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000006411.6", "url": "https://www.ensembl.org/id/ENSBTAT00000006411.6" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000006411.5", "url": "https://www.ensembl.org/id/ENSBTAP00000006411.5" } ] } } ], "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "other", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 506, "start_aa": "Thr", "end_pos": 506, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr506", "evidence": [ { "id": "", "database": "GlyGen", "url": "https://data.glygen.org/" } ], "filter_code": "000000000000000010000.00000000001000.0.01000" } ], "phosphorylation": [], "glycation": [], "keywords": [ "glycoprotein", "glycoprotein_predicted" ], "publication": [], "pathway": [], "orthologs": [], "go_annotation": { "categories": [ { "name": "Molecular Function", "total": 3, "go_terms": [ { "name": "zinc ion binding", "id": "GO:0008270", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008270", "evidence": [ { "database": "UniProtKB", "id": "F6R8Z4", "url": "https://www.uniprot.org/uniprotkb/F6R8Z4" } ], "pmid": "" }, { "name": "identical protein binding", "id": "GO:0042802", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0042802", "evidence": [ { "database": "UniProtKB", "id": "F6R8Z4", "url": "https://www.uniprot.org/uniprotkb/F6R8Z4" } ], "pmid": "" }, { "name": "ubiquitin protein ligase activity", "id": "GO:0061630", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0061630", "evidence": [ { "database": "UniProtKB", "id": "F6R8Z4", "url": "https://www.uniprot.org/uniprotkb/F6R8Z4" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 4, "go_terms": [ { "name": "nucleoplasm", "id": "GO:0005654", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005654", "evidence": [ { "database": "UniProtKB", "id": "F6R8Z4", "url": "https://www.uniprot.org/uniprotkb/F6R8Z4" } ], "pmid": "" }, { "name": "nucleolus", "id": "GO:0005730", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005730", "evidence": [ { "database": "UniProtKB", "id": "F6R8Z4", "url": "https://www.uniprot.org/uniprotkb/F6R8Z4" } ], "pmid": "" }, { "name": "plasma membrane", "id": "GO:0005886", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005886", "evidence": [ { "database": "UniProtKB", "id": "F6R8Z4", "url": "https://www.uniprot.org/uniprotkb/F6R8Z4" } ], "pmid": "" }, { "name": "site of DNA damage", "id": "GO:0090734", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0090734", "evidence": [ { "database": "UniProtKB", "id": "F6R8Z4", "url": "https://www.uniprot.org/uniprotkb/F6R8Z4" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 5, "go_terms": [ { "name": "DNA damage response", "id": "GO:0006974", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006974", "evidence": [ { "database": "UniProtKB", "id": "F6R8Z4", "url": "https://www.uniprot.org/uniprotkb/F6R8Z4" } ], "pmid": "" }, { "name": "protein ubiquitination", "id": "GO:0016567", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016567", "evidence": [ { "database": "UniProtKB", "id": "F6R8Z4", "url": "https://www.uniprot.org/uniprotkb/F6R8Z4" } ], "pmid": "" }, { "name": "negative regulation of tumor necrosis factor-mediated signaling pathway", "id": "GO:0010804", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0010804", "evidence": [ { "database": "UniProtKB", "id": "F6R8Z4", "url": "https://www.uniprot.org/uniprotkb/F6R8Z4" } ], "pmid": "" }, { "name": "negative regulation of interferon-beta production", "id": "GO:0032688", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0032688", "evidence": [ { "database": "UniProtKB", "id": "F6R8Z4", "url": "https://www.uniprot.org/uniprotkb/F6R8Z4" } ], "pmid": "" }, { "name": "replication fork processing", "id": "GO:0031297", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0031297", "evidence": [ { "database": "UniProtKB", "id": "F6R8Z4", "url": "https://www.uniprot.org/uniprotkb/F6R8Z4" } ], "pmid": "" } ] } ] }, "pro_annotation": [], 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"UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "QLERSKYLPLPDAADNIRMALNSGSSPGVGPYYENHGYQPESLYPQQPPTAPPAFEVYPAQYYPPVVPQYTPRVQTHASTPVIYRQPKPPSRTACTSKTKKALCITFTLVVLLAGAILAAVLLWKYMEDECSGMECSSSGTCVSPSLWCDGILHCPSGEDENRCVRLYGPNFILQVYSAQRKSWHPVCQDDWSESYGRAACQDMGYRNSFYSSQGIADDSGATSFMKLNISANDIDLYKKLYHSDVCSSKTVVSLRCIECGVSVKTSRQSRIVGGSNAYSGEWPWQVSLHVQGIHVCGGSIITPEWIVTAAHCVEEPLNNPKIWVAFAGILKQSYMFYGSGYRVAKVISHPNYDSKTKNNDIALMKLQTPLTFNDKVKPVCLPNPGMMLEPTQSCWISGWGATYEKGKTSDDLNAAKVHLIEPRKCNSKYMYDNLITPAMICAGYLRGTVDSCQGDSGGPLVTLKSSVWWLIGDTSWGSGCAKAYRPGVYGNVTVFTDWIYQQMRANS", "length": 508, "header": "tr|F6RBY0-1|F6RBY0_BOVIN Isoform 1 of Transmembrane protease serine 2 OS=Bos taurus OX=9913 GN=TMPRSS2 PE=4 SV=1 CANONICAL=F6RBY0-1" }, "isoforms": [ { "isoform_ac": "A0AAA9RWP8-1", "url": "https://www.uniprot.org/uniprotkb/A0AAA9RWP8/entry", "sequence": { "sequence": 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"https://www.ensembl.org/id/ENSBTAT00000114474.1" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000091048.1", "url": "https://www.ensembl.org/id/ENSBTAP00000091048.1" } ] } }, { "isoform_ac": "A0AAA9T4G7-1", "url": "https://www.uniprot.org/uniprotkb/A0AAA9T4G7/entry", "sequence": { "sequence": "MALNSGSSPGVGPYYENHGYQPESLYPQQPPTAPPAFEVYPAQYYPPVVPQYTPRVQTHASTPVIYRQPKPPSRTACTSKTKKALCITFTLVVLLAGAILAAVLLWKYIRLYGPNFILQVYSAQRKSWHPVCQDDWSESYGRAACQDMGYRNSFYSSQGIADDSGATSFMKLNISANDIDLYKKLYHSDVCSSKTVVSLRCIECGVSVKTSRQSRIVGGSNAYSGEWPWQVSLHVQGIHVCGGSIITPEWIVTAAHCVEEPLNNPKIWVAFAGILKQSYMFYGSGYRVAKVISHPNYDSKTKNNDIALMKLQTPLTFNDKVKPVCLPNPGMMLEPTQSCWISGWGATYEKGKTSDDLNAAKVHLIEPRKCNSKYMYDNLITPAMICAGYLRGTVDSCQGDSGGPLVTLKSSVWWLIGDTSWGSGCAKAYRPGVYGNVTVFTDWIYQQMRANS", "length": 452, "header": "tr|A0AAA9T4G7-1|F6RBY0_BOVIN Computationally mapped isoform of Transmembrane protease serine 2 OS=Bos taurus OX=9913 GN=TMPRSS2 PE=4 SV=1 CANONICAL=F6RBY0-1" }, "locus": { "chromosome": "1", "start_pos": 141747758, "end_pos": 141714022, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000126884.1", "url": "https://www.ensembl.org/id/ENSBTAT00000126884.1" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000090626.1", "url": "https://www.ensembl.org/id/ENSBTAP00000090626.1" } ] } }, { "isoform_ac": "F6RBY0-1", "url": "https://www.uniprot.org/uniprotkb/F6RBY0/entry", "sequence": { "sequence": "QLERSKYLPLPDAADNIRMALNSGSSPGVGPYYENHGYQPESLYPQQPPTAPPAFEVYPAQYYPPVVPQYTPRVQTHASTPVIYRQPKPPSRTACTSKTKKALCITFTLVVLLAGAILAAVLLWKYMEDECSGMECSSSGTCVSPSLWCDGILHCPSGEDENRCVRLYGPNFILQVYSAQRKSWHPVCQDDWSESYGRAACQDMGYRNSFYSSQGIADDSGATSFMKLNISANDIDLYKKLYHSDVCSSKTVVSLRCIECGVSVKTSRQSRIVGGSNAYSGEWPWQVSLHVQGIHVCGGSIITPEWIVTAAHCVEEPLNNPKIWVAFAGILKQSYMFYGSGYRVAKVISHPNYDSKTKNNDIALMKLQTPLTFNDKVKPVCLPNPGMMLEPTQSCWISGWGATYEKGKTSDDLNAAKVHLIEPRKCNSKYMYDNLITPAMICAGYLRGTVDSCQGDSGGPLVTLKSSVWWLIGDTSWGSGCAKAYRPGVYGNVTVFTDWIYQQMRANS", "length": 508, "header": "tr|F6RBY0-1|F6RBY0_BOVIN Isoform 1 of Transmembrane protease serine 2 OS=Bos taurus OX=9913 GN=TMPRSS2 PE=4 SV=1 CANONICAL=F6RBY0-1" }, "locus": { "chromosome": "1", "start_pos": 141747812, "end_pos": 141714022, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000012036.6", "url": "https://www.ensembl.org/id/ENSBTAT00000012036.6" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000012036.5", "url": "https://www.ensembl.org/id/ENSBTAP00000012036.5" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [ "enzyme" ], "publication": [], "pathway": [], "orthologs": [], "go_annotation": { "categories": [ { "name": "Molecular Function", "total": 1, "go_terms": [ { "name": "serine-type endopeptidase activity", "id": "GO:0004252", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0004252", "evidence": [ { "database": "UniProtKB", "id": "F6RBY0", "url": "https://www.uniprot.org/uniprotkb/F6RBY0" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 2, "go_terms": [ { "name": "extracellular region", "id": "GO:0005576", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005576", "evidence": [ { "database": "UniProtKB", "id": "F6RBY0", "url": "https://www.uniprot.org/uniprotkb/F6RBY0" } ], "pmid": "" }, { "name": "plasma membrane", "id": "GO:0005886", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005886", "evidence": [ { "database": "UniProtKB", "id": "F6RBY0", "url": "https://www.uniprot.org/uniprotkb/F6RBY0" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 1, "go_terms": [ { "name": "proteolysis", "id": "GO:0006508", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006508", "evidence": [ { "database": "UniProtKB", "id": "F6RBY0", "url": "https://www.uniprot.org/uniprotkb/F6RBY0" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 229, "end_pos": 231, "annotation": "n_glycosylation_sequon" }, { "start_pos": 492, "end_pos": 494, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], 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"evidence": [ { "id": "XP_005223686", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_005223686" } ] } ], "function": [], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Bos taurus", "taxid": 9913, "evidence": [ { "database": "UniProtKB", "id": "F6Q115", "url": "https://www.uniprot.org/uniprotkb/F6Q115" } ], "common_name": "Bovine", "glygen_name": "Bovine", "reference_species": "Bos taurus [9913]" } ], "gene": [ { "name": "ATF6B", "url": "https://www.uniprot.org/uniprotkb/F6Q115", "locus": { "chromosome": "23", "start_pos": 27264824, "end_pos": 27252845, "strand": "-", "evidence": [ { "database": "Ensembl Gene", "id": "ENSBTAG00000008794", "url": "https://www.ensembl.org/id/ENSBTAG00000008794" } ] } } ], "crossref": [ { "id": "F6Q115", "url": "https://alphafold.ebi.ac.uk/entry/F6Q115", "database": "AlphaFoldDB", "categories": [] }, { "id": "cd14700", "url": 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"Protein" ] }, { "id": "F6Q115-1", "url": "https://www.uniprot.org/uniprotkb/F6Q115-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MAELMLLSEIADPTRFFTDNLLSPEDWDSTLYAGLDEVAEEQTELFRCPEQDVPVSLPKPCLSPLFGSSSLDLGMDVSPPEPPWDSLPIFPARFPPDLQVKSEPSSPCSSSSLSSESSHLSTEPSNQAPGVGEMLVVKSESLAPPLCLLGDDPTSPFETIQINVSTISDDPSDVQIKIEPASPSSSINSEAPLLSAESPSQAFIGEEVLEVKTESPSPQGCLLRDVPGPSPGAVQISMGLSSDGSSGKALPARKPPLQPKPMLITTVPIPPRAVPASTTVLLQPLVQPPPVSPVVLIQGTVRVQPEGPTPPPPRPERKSIVPAPMPGNSCPPEVDAKLLKRQQRMIKNRESACQSRRKKKEYLQGLEARLQAVLADNQQLRRENAALRRRLEALLTENSELKLGSGNRKVVCVMVFLLFIAFNFGPVSISEPPPASISPRMSRGESRPRRHLLEFSAQEPVHGAEPRQHPFQDPEEPQPSPAGHPSFRNLTAFPGDTRELLLRDLDQLFLSSDCRHFNRTESLRLADELSGWVQRHQRGRRKTPQRAQEKQKSQFRKKSPPVQAVPTRPPGPPEGDSVGQLQLYRQPDRSQPEFLDAIDRREDTFYVVSFRRDHLLLPAISHNKTSRPKMSLVMPAMAPNETLSGRGPPGDYEEMMQIECEVMDTRVIHIKTSTVPPSLRKQPSSTPGNATGGPLPASAAASQAHQAAHQPSTSIISDLYDSH", "length": 723, "header": "tr|F6Q115-1|F6Q115_BOVIN Isoform 1 of Activating transcription factor 6 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beta OS=Bos taurus OX=9913 GN=ATF6B PE=3 SV=1 CANONICAL=F6Q115-1" }, "locus": { "chromosome": "23", "start_pos": 27263619, "end_pos": 27254964, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000100219.2", "url": "https://www.ensembl.org/id/ENSBTAT00000100219.2" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000075565.1", "url": "https://www.ensembl.org/id/ENSBTAP00000075565.1" } ] } }, { "isoform_ac": "A0AAA9S0Y6-1", "url": "https://www.uniprot.org/uniprotkb/A0AAA9S0Y6/entry", "sequence": { "sequence": "MAELMLLSEIADPTRFFTDNLLSPEDWDSTLYAGLDEVAEEQTELFRCPEQDVPFGSSSLDLGMDVSPPEPPWDSLPIFPDLQVKSEPSSPCSSSSLSSESSHLSTEPSNQAPGVGEMLVVKSESLAPPLCLLGDDPTSPFETIQINVSTISDDPSDVQIKIEPASPSSSINSEAPLLSAESPSQAFIGEEVLEVKTESPSPQGCLLRDVPGPSPGAVQISMGLSSDGSSGKALPARKPPLQPKPMLITTVPIPPRAVPASTTVLLQPLVQPPPVSPVVLIQGTVRVQPEGPTPPPPRPERKSIVPAPMPGNSCPPEVDAKLLKRQQRMIKNRESACQSRRKKKEYLQGLEARLQAVLADNQQLRRENAALRRRLEALLTENSELKLGSGNRKVVCVMVFLLFIAFNFGPVSISEPPPASISPRMSRGESRPRRHLLEFSAQEPVHGAEPRQHPFQDPEEPQPSPAGHPSFRNLTAFPGDTRELLLRDLDQLFLSSDCRHFNRTESLRLADELSGWVQRHQRGRRKTPQRAQEKQKSQFRKKSPPVQAVPTRPPGPPEGDSVGQLQLYRQPDRSQPEFLDAIDRREDTFYVVSFRRVSFSCGPHPLTLGSPAISLQVKAGEQGQGACQHLFLHPPGLAPLSPGPLAAPSHQPQQDLPAQDVSGDACYGPQ", "length": 670, "header": "tr|A0AAA9S0Y6-1|F6Q115_BOVIN Computationally mapped isoform of Activating transcription factor 6 beta OS=Bos taurus OX=9913 GN=ATF6B PE=3 SV=1 CANONICAL=F6Q115-1" }, "locus": { "chromosome": "23", "start_pos": 27263618, "end_pos": 27254964, "strand": "-", "evidence": [ { "database": "Ensembl 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"MAELMLLSEIADPTRFFTDNLLSPEDWDSTLYAGLDEVAEEQTELFRCPEQDVPVSLPKPCLSPLFGSSSLDLGMDVSPPEPPWDSLPIFPARFPPDLQVKSEPSSPCSSSSLSSESSHLSTEPSNQAPGVGEMLVVKSESLAPPLCLLGDDPTSPFETIQINVSTISDDPSDVQIKIEPASPSSSINSEAPLLSAESPSQAFIGEEVLEVKTESPSPQGCLLRDVPGPSPGAVQISMGLSSDGSSGKALPARKPPLQPKPMLITTVPIPPRAVPASTTVLLQPLVQPPPVSPVVLIQGTVRVQPEGPTPPPPRPERKSIVPAPMPGNSCPPEVDAKLLKRQQRMIKNRESACQSRRKKKEYLQGLEARLQAVLADNQQLRRENAALRRRLEALLTENSELKLGSGNRKVVCVMVFLLFIAFNFGPVSISEPPPASISPRMSRGESRPRRHLLEFSAQEPVHGAEPRQHPFQDPEEPQPSPAGHPSFRNLTAFPGDTRELLLRDLDQLFLSSDCRHFNRTESLRLADELSGWVQRHQRGRRKTPQRAQEKQKSQFRKKSPPVQAVPTRPPGPPEGDSVGQLQLYRQPDRSQPEFLDAIDRREDTFYVVSFRRDHLLLPAISHNKTSRPKMSLVMPAMAPNETLSGRGPPGDYEEMMQIECEVMDTRVIHIKTSTVPPSLRKQPSSTPGNATGGPLPASAAASQAHQAAHQPSTSIISDLYDSH", "length": 723, "header": "tr|F6Q115-1|F6Q115_BOVIN Isoform 1 of Activating transcription factor 6 beta OS=Bos taurus OX=9913 GN=ATF6B PE=3 SV=1 CANONICAL=F6Q115-1" }, "locus": { "chromosome": "23", "start_pos": 27264378, "end_pos": 27254964, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000045345.5", "url": "https://www.ensembl.org/id/ENSBTAT00000045345.5" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000042742.3", "url": "https://www.ensembl.org/id/ENSBTAP00000042742.3" } ] } } ], "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "other", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 309, "start_aa": "Thr", "end_pos": 309, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr309", "evidence": [ { "id": "", "database": "GlyGen", "url": "https://data.glygen.org/" } ], "filter_code": "000000000000000010000.00000000001000.0.01000" }, { "glytoucan_ac": "", "type": "O-linked", "subtype": "other", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } 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"MDETLAEFFRRTILKIPMTEMMTILKTWNFLSENQLQTVNFRQRKESIVQDLVLLCEENHASLNDAAHLDIIYTQFHRHQKIWDVFQMSKAPGDDIDLFDMEQFKSSFKKILQRALKNVTVSFRDAEENSVWIRIAWGTQYKKPNQYKPAYVVYYSQTPYAFTSSSRLKSNLPLLGQALTVASKHHQIVKMDLRSRYLDSLKAIVFKQYNQSFETHNCTTSLQEGSLGLDINMDSRIIHENKVEKERVQRVTQEIFGDYPQPRLEFAQYKLETKFKSDLNGGILAEREEPLRCLVKFSSPHLLEALKSLAPAGIADAPLSPLLTCIPNKGKNYFKIRDK", "length": 339, "header": "tr|F1N7E6-1|F1N7E6_BOVIN Isoform 1 of Centromere protein N OS=Bos taurus OX=9913 GN=CENPN PE=3 SV=1 CANONICAL=F1N7E6-1" }, "isoforms": [ { "isoform_ac": "A0AAA9RX88-1", "url": "https://www.uniprot.org/uniprotkb/A0AAA9RX88/entry", "sequence": { "sequence": 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"https://www.uniprot.org/uniprotkb/A0AAA9T333/entry", "sequence": { "sequence": "MDETLAEFFRRTILKIPMTEMMTILKTWNFLSENQLQTVNFRQRKESIVQDLVLLCEENHASLNDAAHLDIICDDIDLFDMEQFKSSFKKILQRALKNVTVSFRDAEENSVWIRIAWGTQYKKPNQYKPAYVVYYSQTPYAFTSSSRLKSNLPLLGQALTVASKHHQIVKMDLRSRYLDSLKAIVFKQYNQSFETHNCTTSLQEGSLGLDINMDSRIIHENKVEKERVQRVTQEIFGDYPQPRLEFAQYKLETKFKSDLNGGILAEREEPLRCLVKFSSPHLLEALKSLAPAGIADAPLSPLLTCIPNKGKNYFKIRDK", "length": 319, "header": "tr|A0AAA9T333-1|F1N7E6_BOVIN Computationally mapped isoform of Centromere protein N OS=Bos taurus OX=9913 GN=CENPN PE=3 SV=1 CANONICAL=F1N7E6-1" }, "locus": { "chromosome": "18", "start_pos": 7719273, "end_pos": 7702728, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000106359.2", "url": "https://www.ensembl.org/id/ENSBTAT00000106359.2" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000091028.1", "url": "https://www.ensembl.org/id/ENSBTAP00000091028.1" } ] } }, { "isoform_ac": "A0AAA9T9Y9-1", "url": "https://www.uniprot.org/uniprotkb/A0AAA9T9Y9/entry", "sequence": { "sequence": "MDETLAEFFRRTILKIPMTEMMTILKTWNFLSENQLQTVNFRQRKESIVQDLVLLCEENHASLNDAAHLDIIYTQFHRHQKIWDVFQMSKAPGDDIDLFDMEQFKSSFKKILQRALKNVTVSFRDAEENSVWIRIAWGTQYKKPNQYKPAYVVYYSQTPYAFTSSSRLKSNLPLLGQSFETHNCTTSLQEGSLGLDINMDSRIIHENKVEKERVQRVTQEIFGDYPQPRLEFAQYKLETKFKSDLNGGILAEREEPLRCLVKFSSPHLLEALKSLAPAGIADAPLSPLLTCIPNKGKNYFKIRDK", "length": 305, "header": "tr|A0AAA9T9Y9-1|F1N7E6_BOVIN Computationally mapped isoform of Centromere protein N OS=Bos taurus OX=9913 GN=CENPN PE=3 SV=1 CANONICAL=F1N7E6-1" }, "locus": { "chromosome": "18", "start_pos": 7719273, "end_pos": 7702728, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000134246.2", "url": "https://www.ensembl.org/id/ENSBTAT00000134246.2" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000093450.1", "url": "https://www.ensembl.org/id/ENSBTAP00000093450.1" } ] } }, { "isoform_ac": "A0AAA9U0M3-1", "url": "https://www.uniprot.org/uniprotkb/A0AAA9U0M3/entry", "sequence": { "sequence": "MSAKEMDETLAEFFRRTILKIPMTEMMTILKTWNFLSENQLQTVNFRQRKESIVQDLVLLCEENHASLNDAAHLDIIYTQFHRHQKIWDVFQMSKAPGDDIDLFDMEQFKSSFKKILQRALKNVTVSFRDAEENSVWIRIAWGTQYKKPNQYKPAYVVYYSQTPYAFTSSSRLKSNLPLLGQALTVASKHHQIVKMDLRSRYLDSLKAIVFKQYNQSFETHNCTTSLQEGSLGLDINMDSRIIHENKVEKERVQRVTQEIFGDYPQPRLEFAQYKLETKFKSDLNGGILAEREEPLRCLVKFSSPHLLEALKSLAPAGIADAPLSPLLTCIPNKGKNYFKIRDK", "length": 344, "header": "tr|A0AAA9U0M3-1|A0AAA9U0M3_BOVIN Computationally mapped isoform of Centromere protein N OS=Bos taurus OX=9913 GN=CENPN PE=3 SV=1 CANONICAL=F1N7E6-1" }, "locus": { "chromosome": "18", "start_pos": 7719273, "end_pos": 7701130, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000088988.2", "url": "https://www.ensembl.org/id/ENSBTAT00000088988.2" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000103509.1", "url": "https://www.ensembl.org/id/ENSBTAP00000103509.1" } ] } }, { "isoform_ac": "F1N7E6-1", "url": "https://www.uniprot.org/uniprotkb/F1N7E6/entry", "sequence": { "sequence": "MDETLAEFFRRTILKIPMTEMMTILKTWNFLSENQLQTVNFRQRKESIVQDLVLLCEENHASLNDAAHLDIIYTQFHRHQKIWDVFQMSKAPGDDIDLFDMEQFKSSFKKILQRALKNVTVSFRDAEENSVWIRIAWGTQYKKPNQYKPAYVVYYSQTPYAFTSSSRLKSNLPLLGQALTVASKHHQIVKMDLRSRYLDSLKAIVFKQYNQSFETHNCTTSLQEGSLGLDINMDSRIIHENKVEKERVQRVTQEIFGDYPQPRLEFAQYKLETKFKSDLNGGILAEREEPLRCLVKFSSPHLLEALKSLAPAGIADAPLSPLLTCIPNKGKNYFKIRDK", "length": 339, "header": "tr|F1N7E6-1|F1N7E6_BOVIN Isoform 1 of Centromere protein N OS=Bos taurus OX=9913 GN=CENPN PE=3 SV=1 CANONICAL=F1N7E6-1" }, "locus": { "chromosome": "18", "start_pos": 7719273, "end_pos": 7702728, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000015452.6", "url": "https://www.ensembl.org/id/ENSBTAT00000015452.6" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000015452.4", "url": "https://www.ensembl.org/id/ENSBTAP00000015452.4" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [], "orthologs": [], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 3, "go_terms": [ { "name": "nucleus", "id": "GO:0005634", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005634", "evidence": [ { "database": "UniProtKB", "id": "F1N7E6", "url": "https://www.uniprot.org/uniprotkb/F1N7E6" } ], "pmid": "" }, { "name": "chromosome, centromeric region", "id": "GO:0000775", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000775", "evidence": [ { "database": "UniProtKB", "id": "F1N7E6", "url": "https://www.uniprot.org/uniprotkb/F1N7E6" } ], "pmid": "" }, { "name": "nucleoplasm", "id": "GO:0005654", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005654", "evidence": [ { "database": "UniProtKB", "id": "F1N7E6", "url": "https://www.uniprot.org/uniprotkb/F1N7E6" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 2, "go_terms": [ { "name": "chromosome segregation", "id": "GO:0007059", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007059", "evidence": [ { "database": "UniProtKB", "id": "F1N7E6", "url": "https://www.uniprot.org/uniprotkb/F1N7E6" } ], "pmid": "" }, { "name": "CENP-A containing chromatin assembly", "id": "GO:0034080", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0034080", "evidence": [ { "database": "UniProtKB", "id": "F1N7E6", "url": "https://www.uniprot.org/uniprotkb/F1N7E6" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 118, "end_pos": 120, "annotation": "n_glycosylation_sequon" }, { "start_pos": 210, "end_pos": 212, "annotation": "n_glycosylation_sequon" }, { "start_pos": 217, "end_pos": 219, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 118, "end_pos": 120 }, { "start_pos": 210, "end_pos": 212 }, { "start_pos": 217, "end_pos": 219 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": 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{ "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ], "tool_support": { "graph_view": "yes" } }, { "uniprot_canonical_ac": "F1N4T6-1", "uniprot_ac": "F1N4T6", "uniprot_id": "F1N4T6_BOVIN", "mass": { "chemical_mass": 38923.0, "monoisotopic_mass": 38923.0 }, "refseq": { "ac": "NP_001291212", "name": "SAC3 domain-containing protein 1", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001291212" }, "gene_names": [ { "name": "SAC3D1", "type": "recommended", "evidence": [ { "id": "F1N4T6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1N4T6" } ] }, { "name": "SAC3D1", "type": "synonym", "evidence": [ { "id": "NP_001291212", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001291212" } ] } ], "protein_names": [ { "name": "SAC3 domain containing 1", "type": "synonym", "evidence": [ { "id": "F1N4T6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1N4T6/entry#names_and_taxonomy" } ] }, { "name": "SAC3 domain-containing protein 1", "type": "synonym", "evidence": [ { "id": "NP_001291212", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001291212" } ] } ], "function": [], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Bos taurus", "taxid": 9913, "evidence": [ { "database": "UniProtKB", "id": "F1N4T6", "url": "https://www.uniprot.org/uniprotkb/F1N4T6" } ], "common_name": "Bovine", "glygen_name": "Bovine", "reference_species": "Bos taurus [9913]" } ], "gene": [ { "name": "SAC3D1", "url": "https://www.uniprot.org/uniprotkb/F1N4T6", "locus": { "chromosome": "29", "start_pos": 43259767, "end_pos": 43254472, "strand": "-", "evidence": [ { "database": "Ensembl Gene", "id": "ENSBTAG00000002248", "url": "https://www.ensembl.org/id/ENSBTAG00000002248" } ] } } ], "crossref": [ { "id": "F1N4T6", "url": "https://alphafold.ebi.ac.uk/entry/F1N4T6", "database": "AlphaFoldDB", "categories": [] }, { "id": "ENSBTAG00000002248", "url": "https://bgee.org/?page=gene&gene_id=ENSBTAG00000002248", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "507750", "url": "https://www.ncbi.nlm.nih.gov/gene/507750", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR000717", "url": "https://www.ebi.ac.uk/interpro/entry/IPR000717", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR005062", "url": "https://www.ebi.ac.uk/interpro/entry/IPR005062", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR045107", "url": "https://www.ebi.ac.uk/interpro/entry/IPR045107", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "bta:507750", "url": "https://www.genome.jp/dbget-bin/www_bget?bta:507750", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "IFTHAYN", "url": "https://omabrowser.org/oma/group/IFTHAYN/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "F1N4T6", "url": "https://www.orthodb.org/?gene=F1N4T6", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR12436", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR12436", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR12436:SF38", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR12436:SF38", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF03399", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF03399", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "NP_001291212", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001291212", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0AAA9RYJ6", "url": "https://www.uniprot.org/uniprotkb/A0AAA9RYJ6", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0AAA9RYJ6-1", "url": "https://www.uniprot.org/uniprotkb/A0AAA9RYJ6-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "F1N4T6", "url": "https://www.uniprot.org/uniprotkb/F1N4T6", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "F1N4T6-1", "url": "https://www.uniprot.org/uniprotkb/F1N4T6-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MPGYELPVGTCLDMCPAAERAQREKERRLHRFEVVPGCRRDRPRADPQRAVKEYSRPAAGKNRPPPSQLRPPSVLLATVRYLASEVAERTDASCAEVASFVADRLRAVRLDLALQTASDVETALVLESALAVLLAVVARLGPNATHGPVDPMLLQAQVQESFGSLRRCYALGAGPHPRQATFQGLFLLYNLGSVEALHEILRLPAALRSCPALRTALAVDSAFREGNAARLFRLLRTLPYLQSCAVQCHVGRARRGALARLARALSTPKGQTLPLGFMVHLLALDGPNEARDLCQAHGLPLDGQERVVFLRGRYTEEGLPPAGTCQILVGNKLGGRTLEDVAMAEEEDEAVDRPTTEV", "length": 358, "header": "tr|F1N4T6-1|F1N4T6_BOVIN Isoform 1 of SAC3 domain containing 1 OS=Bos taurus OX=9913 GN=SAC3D1 PE=4 SV=3 CANONICAL=F1N4T6-1" }, "isoforms": [ { "isoform_ac": "A0AAA9RYJ6-1", "url": "https://www.uniprot.org/uniprotkb/A0AAA9RYJ6/entry", "sequence": { "sequence": "MPGYELPVGTCLDMCPAAERAQREKERRLHRFEVVPGCRRDRPRADPQRAVKEYSRPAAGKNRPPPSQLRPPSVLLATVRYLASEVAERTDASCAEVASFVADRLRAVRLDLALQTASDVETALVLESALAVLLAVVARLGPNATHGPVDPMLLQAQVQESFGSLRRCYALGAGPHPRQATFQGLFLLYNLGESGSPRQSRAGTVEARRPSTRFCGCLQLCVPARPCAPPWQL", "length": 233, "header": "tr|A0AAA9RYJ6-1|F1N4T6_BOVIN Computationally mapped isoform of SAC3 domain containing 1 OS=Bos taurus OX=9913 GN=SAC3D1 PE=4 SV=1 CANONICAL=F1N4T6-1" }, "locus": { "chromosome": "29", "start_pos": 43256243, "end_pos": 43254792, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000119008.1", "url": "https://www.ensembl.org/id/ENSBTAT00000119008.1" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000074880.1", "url": "https://www.ensembl.org/id/ENSBTAP00000074880.1" } ] } }, { "isoform_ac": "F1N4T6-1", "url": "https://www.uniprot.org/uniprotkb/F1N4T6/entry", "sequence": { "sequence": "MPGYELPVGTCLDMCPAAERAQREKERRLHRFEVVPGCRRDRPRADPQRAVKEYSRPAAGKNRPPPSQLRPPSVLLATVRYLASEVAERTDASCAEVASFVADRLRAVRLDLALQTASDVETALVLESALAVLLAVVARLGPNATHGPVDPMLLQAQVQESFGSLRRCYALGAGPHPRQATFQGLFLLYNLGSVEALHEILRLPAALRSCPALRTALAVDSAFREGNAARLFRLLRTLPYLQSCAVQCHVGRARRGALARLARALSTPKGQTLPLGFMVHLLALDGPNEARDLCQAHGLPLDGQERVVFLRGRYTEEGLPPAGTCQILVGNKLGGRTLEDVAMAEEEDEAVDRPTTEV", "length": 358, "header": "tr|F1N4T6-1|F1N4T6_BOVIN Isoform 1 of SAC3 domain containing 1 OS=Bos taurus OX=9913 GN=SAC3D1 PE=4 SV=3 CANONICAL=F1N4T6-1" }, "locus": { "chromosome": "29", "start_pos": 43256659, "end_pos": 43254792, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000002904.8", "url": "https://www.ensembl.org/id/ENSBTAT00000002904.8" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000002904.6", "url": "https://www.ensembl.org/id/ENSBTAP00000002904.6" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [ { "id": "bta:507750", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?bta:507750", "resource": "KEGG Pathway" } ], "orthologs": [ { "uniprot_canonical_ac": "A6H687-1", "protein_name": "SAC3 domain-containing protein 1", "gene_name": "Sac3d1", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MGRFKGENRSQARWIMGGVSKGRGSGKSRKPRQAAFGQTGARVCPSSPQQDAVPRFRWPGDAECASSTHTPTMSGCKLPMGLCPDMCPAAERARRERERRLHRLEVEPGGRGNAPRADPKRTVKEYSRPAAGKPRPPPSLLRPPPVLLATVRYLAGEVAGRGDVSCAEVASFVADRLRAVRLDLSLQGVDDADAATVLEAALATLLAVVARVRPEETRGAADPVLLQTQVQEGFGSLRRCYARGKGPYPRQAAFQGLFLLYNLGSVEALQEVLQLPAALRACPPLQAALAVDAAFREDNHARLFRLLRTLPYLQSCAVQEHIGYARRKALARLSRALSTPKGQTLPLDFIEHFLALDGLQEARDLCQAHGLTLDKDRVVFLRGQYSEEGLPPPGAYHILVGNKLQGHTLEDVVMAEEGDIHRPGSAA", "length": 427 }, "evidence": [ { "id": "F1N4T6", "url": "https://omabrowser.org/oma/group/F1N4T6/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "A6NKF1-1", "protein_name": "SAC3 domain-containing protein 1", "gene_name": "SAC3D1", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MAGRRAQTGSAPPRPAAPHPRPASRAFPQHCRPRDAERPPSPRSPLMPGCELPVGTCPDMCPAAERAQREREHRLHRLEVVPGCRQDPPRADPQRAVKEYSRPAAGKPRPPPSQLRPPSVLLATVRYLAGEVAESADIARAEVASFVADRLRAVLLDLALQGAGDAEAAVVLEAALATLLTVVARLGPDAARGPADPVLLQAQVQEGFGSLRRCYARGAGPHPRQPAFQGLFLLYNLGSVEALHEVLQLPAALRACPPLRKALAVDAAFREGNAARLFRLLQTLPYLPSCAVQCHVGHARREALARFARAFSTPKGQTLPLGFMVNLLALDGLREARDLCQAHGLPLDGEERVVFLRGRYVEEGLPPASTCKVLVESKLRGRTLEEVVMAEEEDEGTDRPGSPA", "length": 404 }, "evidence": [ { "id": "F1N4T6", "url": "https://omabrowser.org/oma/group/F1N4T6/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "D3ZT97-1", "protein_name": "SAC3 domain containing 1", "gene_name": "Sac3d1", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MGRFKGENRSQARWIMGGVSKGRRSRKSRKPGEEGWASQTGSQACSPSPRQDAVPRFRWPSDAECASSTHSPAMSDYKLPMGLCPDMCPAAERARRERERRLHRLEVEPGGCGNAPRADPRRTVKEYSRPAAGKPRPPPSLLRPPPVLLATVRYLAGEVADRTDVSCAEVASFVADRLRAVRLDLSLQGVDDAEAAAVLEPALATLLVVVARMRPEETRGVADPVLLQTQVQEGFGSLRRCYARGKAPHPRQAAFQGLFLLYNLGSVEALQEVLQLPAALRACPPLQTALAVDSAFREDNYARLFRLLRTLPYLQSCAVQEHIGYARRKALSRLSRALSTPRGQTLPLDFIVHLLALDGLQEAQDLCQAHGLTLDKDRVIFLRGQYSEEGLPSPGTCHLLVGSKLQGHTLEEVVMAEEEKDIHRPGSPT", "length": 429 }, "evidence": [ { "id": "F1N4T6", "url": "https://omabrowser.org/oma/group/F1N4T6/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "F1RQT0-1", "protein_name": "SAC3 domain containing 1", "gene_name": "SAC3D1", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MPGYELPLGTCLDMCPANERTRREKECRLHRFEVAPGSPGDRPRADPQRAVKEYSRPAAGKARPPPSQLRPPSVLLATVRYLAGEVAERTDASRAEVASFVADRLRAVRLDLALQGAGDAEAALVLEAALAVLLAVVARLEPNASHGLADPMLLQAQVQESFGSLRRCYALGAGPHPRQATFQGLFLLYNLGSVEALHEVLQLPAALRSCPALRTALAVDSAFREGNAARLFRLLRSLPYLQSCAVQCHVGRARRGALARLARALSTPKGQTVPLGFMVHLLALDGPEEARDLCQAHGLPLDGQERVVFLRGRYREEGPPPAGTCQMLVESKLGGRTLEEVVMAEEEDEAVNRPESPA", "length": 358 }, "evidence": [ { "id": "F1N4T6", "url": "https://omabrowser.org/oma/group/F1N4T6/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "Q67XV2-1", "protein_name": "SAC3 family protein C", "gene_name": "SAC3C", "tax_id": 3702, "organism": "Arabidopsis thaliana", "sequence": { "sequence": "MNRRNRGSSSSSSRVSNTYGNRQFSDNPRTGSGGGVNESFQRRSDAPHKRNNEKDESKHKDEDPADVSLIVGTCSSMCPERERVTRERLRDLAVFERLYGNPSKSSTEIAVKKFCRTLSAADVQASDVRPLPVLEETLRYLLSLLDSKEHPFEVVHDFIFDRTRSIRQDLSIQNLANERVIYLYEEMVKFHVISHERLQSCSGTSISSMHHLNMEQLAKTLTSLYNIYDANRKPDYIYENEAEFRSLYVLLHLNPSSGVMGEPLSLWFRKLTFALVKSKEICFVRNLLRLYRMGNYKNFLSRTASEATYLQYCISEHHIREMRLVAVQYINNVCYKLQPYPLLRLSQNLKMKELDVESLCHECGLETCTDPDGFTVLPVKQSTFRSPEDKFKVYDLIGIERIKMSI", "length": 406 }, "evidence": [ { "id": "F1N4T6", "url": "https://omabrowser.org/oma/group/F1N4T6/", "database": "OMA" } ], "glygen_name": "Arabidopsis", "common_name": "Mouse-ear cress" }, { "uniprot_canonical_ac": "Q9VSZ4-1", "protein_name": "SAC3/GANP/THP3 conserved domain-containing protein", "gene_name": "Dmel\\CG3437", "tax_id": 7227, "organism": "Drosophila melanogaster", "sequence": { "sequence": "MAQVRGSCESFCPDGEAKMRIREKLLHYFELKNGQKNKPGVLVKEFTRSAADVKMPMPKEMRTEAALTKTVEYLLKDIILDTRKPYNVAYDFIFDRLRAVRREIVIQMYDASQKICLLEPIVMFLAYSRYRLCEEPIEKFDLKICNQHLQECLTGVLCCYEELEDLESSREPTVRELERRCFIESLYQLFNLGSPESFTRALTLPDYVRRDATFKLCFGICLAFQQGNLYRVLMGVPQLPHILCAVAAAKLQVIRRSLLQIFTHAYNNKQLTVPVPYLLRLLLFDGPTGLQDQCRHYNISLTADRKAVQFNKTDFNHNAEVFTPQHERFVESKLKRIYIPEVLLLKKFN", "length": 349 }, "evidence": [ { "id": "F1N4T6", "url": "https://omabrowser.org/oma/group/F1N4T6/", "database": "OMA" } ], "glygen_name": "Fruit fly", "common_name": "Fruit fly" } ], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 4, "go_terms": [ { "name": "nucleus", "id": "GO:0005634", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005634", "evidence": [ { "database": "UniProtKB", "id": "F1N4T6", "url": "https://www.uniprot.org/uniprotkb/F1N4T6" } ], "pmid": "" }, { "name": "centrosome", "id": "GO:0005813", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005813", "evidence": [ { "database": "UniProtKB", "id": "F1N4T6", "url": "https://www.uniprot.org/uniprotkb/F1N4T6" } ], "pmid": "" }, { "name": "spindle", "id": "GO:0005819", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005819", "evidence": [ { "database": "UniProtKB", "id": "F1N4T6", "url": "https://www.uniprot.org/uniprotkb/F1N4T6" } ], "pmid": "" }, { "name": "cytosol", "id": "GO:0005829", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005829", "evidence": [ { "database": "UniProtKB", "id": "F1N4T6", "url": "https://www.uniprot.org/uniprotkb/F1N4T6" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 2, "go_terms": [ { "name": "centrosome duplication", "id": "GO:0051298", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0051298", "evidence": [ { "database": "UniProtKB", "id": "F1N4T6", "url": "https://www.uniprot.org/uniprotkb/F1N4T6" } ], "pmid": "" }, { "name": "spindle assembly", "id": "GO:0051225", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0051225", "evidence": [ { "database": "UniProtKB", "id": "F1N4T6", "url": "https://www.uniprot.org/uniprotkb/F1N4T6" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 143, "end_pos": 145, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [ { "pdb_id": "AF-F1N4T6-F1", "pdb_chain": "global", "start_pos": 1, "end_pos": 358, "overlap": "1.0", "method": "AlphaFold", "type": "alphafold", "resolution": -1.0, "url": "https://data.glygen.org/ln2downloads/pdb/current/AF-F1N4T6-F1.pdb", "url_external": "https://alphafold.ebi.ac.uk/entry/F1N4T6" } ], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "F1N4T6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1N4T6" }, { "id": "PS50250", "database": "PROSITE", "url": "https://prosite.expasy.org/PS50250" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "PCI", "eco_id": "ECO_0000259", "start_pos": 157, "end_pos": 322, "start_aa": "Gln", "end_aa": "Ala", "glycosite_overlap": [] } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" }, { "name": "homologset.oma", "label": "OMA Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 143, "end_pos": 145 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ], "tool_support": { "graph_view": "yes" } }, { "uniprot_canonical_ac": "F6PQR5-1", "uniprot_ac": "F6PQR5", "uniprot_id": "F6PQR5_BOVIN", "mass": { "chemical_mass": 77661.0, "monoisotopic_mass": 77661.0 }, "refseq": { "ac": "XP_002698206", "name": "F-box/LRR-repeat protein 18", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_002698206" }, "gene_names": [ { "name": "FBXL18", "type": "recommended", "evidence": [ { "id": "F6PQR5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F6PQR5" } ] }, { "name": "FBXL18", "type": "synonym", "evidence": [ { "id": "XP_002698206", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_002698206" } ] } ], "protein_names": [ { "name": "F-box and leucine rich repeat protein 18", "type": "synonym", "evidence": [ { "id": "F6PQR5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F6PQR5/entry#names_and_taxonomy" } ] }, { "name": "F-box/LRR-repeat protein 18", "type": "synonym", "evidence": [ { "id": "XP_002698206", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_002698206" } ] } ], "function": [], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Bos taurus", "taxid": 9913, "evidence": [ { "database": "UniProtKB", "id": "F6PQR5", "url": "https://www.uniprot.org/uniprotkb/F6PQR5" } ], "common_name": "Bovine", "glygen_name": "Bovine", "reference_species": "Bos taurus [9913]" } ], "gene": [ { "name": "FBXL18", "url": "https://www.uniprot.org/uniprotkb/F6PQR5", "locus": { "chromosome": "25", "start_pos": 38864054, "end_pos": 38809844, "strand": "-", "evidence": [ { "database": "Ensembl Gene", "id": "ENSBTAG00000010264", "url": "https://www.ensembl.org/id/ENSBTAG00000010264" } ] } } ], "crossref": [ { "id": "F6PQR5", "url": "https://alphafold.ebi.ac.uk/entry/F6PQR5", "database": "AlphaFoldDB", "categories": [] }, { "id": "ENSBTAG00000010264", "url": "https://bgee.org/?page=gene&gene_id=ENSBTAG00000010264", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "cd22128", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd22128", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "789838", "url": "https://www.ncbi.nlm.nih.gov/gene/789838", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR001810", "url": "https://www.ebi.ac.uk/interpro/entry/IPR001810", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR032675", "url": "https://www.ebi.ac.uk/interpro/entry/IPR032675", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR036047", "url": "https://www.ebi.ac.uk/interpro/entry/IPR036047", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR045627", "url": "https://www.ebi.ac.uk/interpro/entry/IPR045627", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR047948", "url": "https://www.ebi.ac.uk/interpro/entry/IPR047948", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "bta:789838", "url": "https://www.genome.jp/dbget-bin/www_bget?bta:789838", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "F6PQR5", "url": "https://www.orthodb.org/?gene=F6PQR5", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR16134", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR16134", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR16134:SF19", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR16134:SF19", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF12937", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF12937", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF19729", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF19729", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "XP_002698206", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_002698206", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0AAA9S072", "url": "https://www.uniprot.org/uniprotkb/A0AAA9S072", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0AAA9S072-1", "url": "https://www.uniprot.org/uniprotkb/A0AAA9S072-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0AAA9S368", "url": "https://www.uniprot.org/uniprotkb/A0AAA9S368", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0AAA9S368-1", "url": "https://www.uniprot.org/uniprotkb/A0AAA9S368-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0AAA9T7P6", "url": "https://www.uniprot.org/uniprotkb/A0AAA9T7P6", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0AAA9T7P6-1", "url": "https://www.uniprot.org/uniprotkb/A0AAA9T7P6-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0AAA9TY08", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TY08", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0AAA9TY08-1", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TY08-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "F1MNH8", "url": "https://www.uniprot.org/uniprotkb/F1MNH8", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "F1MNH8-1", "url": "https://www.uniprot.org/uniprotkb/F1MNH8-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "F6PQR5", "url": "https://www.uniprot.org/uniprotkb/F6PQR5", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "F6PQR5-1", "url": "https://www.uniprot.org/uniprotkb/F6PQR5-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MASSGEDTCDDSDTAPVADSAHLLGFSDEILLHILSHVPSTDLVLNVRRTCRKLAALCLDKSLTHTVLLQKDYEASEDKVKRLVKEIGRDVQQLSMAGCYWLSGTTVEHVARCRGLVRVNLSGCPLTSLRLSKVLSALPHLRSLAIDVSPGFDASQLSSECKATLSRVRELKQTLYTPSYGVVPCCTSLEKLLLYFEILDRTREGAVLSGQLMVGQSNVPHYQHLRVFYARLAPGYINQEVVRLYLAVLSDRTPENLHAFLISVPGSFAESGATRNLLESMARNVALDALQLPKSWLNGSALLQHMKFSSPFYFSFSRCALSGGHLLQRVIDGGRDLQSLAGLNLSGCAHCLAPDCLLRKAEDDIDPAILEALVAACPNLRHLNLSAAHHHSPAGPSQHLCQLLARLPHLRSLSLPVCAVADSPPRADRAPIPPTMRAVPRGFGKKVRIGVQSVPFPGPAGPQPSSVFWSLLKNVPFLDRLELIGSNFSSAMPRNEPAIRNSLPPCSRAQSVGDAEVAAIGQLAFLRHLTLAQLPSILTGSGLVSIGLQCQQLQSLSLAHLGLMGKVVYMSGLSDMLKHCKRLKDLRLEQPYFSANAQFFQALSQCSALQRLCLVSRSGTLQPEAVLAFMARCLHVVVCHLFTGESLSTCRSLQQALLRSFQAERPALNVVVFPLLHEGLTDVIRDVPMVHLDEVTLFKSRVAEEPPNLWW", "length": 711, "header": "tr|F6PQR5-1|F6PQR5_BOVIN Isoform 1 of F-box and leucine rich repeat protein 18 OS=Bos taurus OX=9913 GN=FBXL18 PE=4 SV=4 CANONICAL=F6PQR5-1" }, "isoforms": [ { "isoform_ac": "A0AAA9S072-1", "url": "https://www.uniprot.org/uniprotkb/A0AAA9S072/entry", "sequence": { "sequence": "MASSGEDTCDDSDTAPVADSAHLLGFSDEILLHILSHVPSTDLVLNVRRTCRKLAALCLDKSLTHTVLLQKDYEASEDKVKRLVKEIGRDVQQLSMAGCYWLSGTTVEHVARCRGLVRVNLSGCPLTSLRLSKVLSALPHLRSLAIDVSPGFDASQLSSECKATLSRVRELKQTLYTPSYGVVPCCTSLEKLLLYFEILDRTREGAVLSGQLMVGQSNVPHYQHLRVFYARLAPGYINQEVVRLYLAVLSDRTPENLHAFLISVPGSFAESGATRNLLESMARNVALDALQLPKSWLNGSALLQHMKFSSPFYFSFSRCALSGGHLLQRVIDGGRDLQSLAGLNLSGCAHCLAPDCLLRKAEDDIDPAILEALVAACPNLRHLNLSAAHHHSPAGPSQHLCQLLARLPHLRSLSLPVCAVADSPPRADRAPIPPTMRAVPRGFGKKVRIGVQSVPFPGPAGPQPSSVFWSLLKNVPFLDRLELIGSNFSSAMPRNEPAIRNSLPPCSRAQSVGDAEVAAIGQLAFLRHLTLAQLPSILTGSGLVSIGLQCQQLQSLSLAHLGLMGKVVYMSGLSDMLKHCKRLKDLRLEQPYFSANAQFFQALSQCSALQRLCLVSRSGTLQPEAVLAFMARCLHVVVCHLFTGESLSTCRSLQQALLRSLS", "length": 662, "header": "tr|A0AAA9S072-1|F6PQR5_BOVIN Computationally mapped isoform of F-box and leucine rich repeat protein 18 OS=Bos taurus OX=9913 GN=FBXL18 PE=4 SV=1 CANONICAL=F6PQR5-1" }, "locus": { "chromosome": "25", "start_pos": 38863420, "end_pos": 38810196, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000114766.2", "url": "https://www.ensembl.org/id/ENSBTAT00000114766.2" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000075458.1", "url": "https://www.ensembl.org/id/ENSBTAP00000075458.1" } ] } }, { "isoform_ac": "A0AAA9S368-1", "url": "https://www.uniprot.org/uniprotkb/A0AAA9S368/entry", "sequence": { "sequence": "MASSGEDTCDDSDTAPVADSAHLLGFSDEILLHILSHVPSTDLVLNVRRTCRKLAALCLDKSLTHTVLLQKDYEASEDKVKRLVKEIGRDVQQLSMAGCYWLSGTTVEHVARCRGLVRVNLSGCPLTSLRLSKVLSALPHLRSLAIDVSPGFDASQLSSECKATLSRVRELKQTLYTPSYGVVPCCTSLEKLLLYFEILDRTREGAVLSGQLMVGQSNVPHYQHLRVFYARLAPGYINQEVVRLYLAVLSDRTPENLHAFLISVPGSFAESGATRNLLESMARNVALDALQLPKSWLNGSALLQHMKFSSPFYFSFSRCALSGGHLLQRVIDGGRDLQSLAGLNLSGCAHCLAPDCLLRKAEDDIDPAILEALVAACPNLRHLNLSAAHHHSPAGPSQHLCQLLARLPHLRSLSLPVCAVADSPPRADRAPIPPTMRAVPRGFGKKVRIGVQSVPFPGPAGPQPSSVFWSLLKNVPFLDRLELIGSNFSSAMPRNEPAIRNSLPPCSRAQSVGDAEVAAIGQLAFLRHLTLAQLPSILTGSGLVSIGLQCQQLQSLSLAHLGLMGKVVYMSGLSDMLKHCKRLKDLRLEQPYFSANAQFFQALSQCSALQRLCLVSRSGTLQPEAVLAFMARCLHVVVCHLFTGESLSTCRSLQQALLRRWIPYH", "length": 665, "header": "tr|A0AAA9S368-1|F6PQR5_BOVIN Computationally mapped isoform of F-box and leucine rich repeat protein 18 OS=Bos taurus OX=9913 GN=FBXL18 PE=4 SV=1 CANONICAL=F6PQR5-1" }, "locus": { "chromosome": "25", "start_pos": 38828390, "end_pos": 38810196, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000102027.2", "url": "https://www.ensembl.org/id/ENSBTAT00000102027.2" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000079548.1", "url": "https://www.ensembl.org/id/ENSBTAP00000079548.1" } ] } }, { "isoform_ac": "A0AAA9T7P6-1", "url": "https://www.uniprot.org/uniprotkb/A0AAA9T7P6/entry", "sequence": { "sequence": "MASSGEDTCDDSDTAPVADSAHLLGFSDEILLHILSHVPSTDLVLNVRRTCRKLAALCLDKSLTHTVLLQKDYEASEDKVKRLVKEIGRDVQQLSMAGCYWLSGTTVEHVARCRGLVRVNLSGCPLTSLRLSKVLSALPHLRSLAIDVSPGFDASQLSSECKATLSRVRELKQTLYTPSYGVVPCCTSLEKLLLYFEILDRTREGAVLSGQLMVGQSNVPHYQHLRVFYARLAPGYINQEVVRLYLAVLSDRTPENLHAFLISVPGSFAESGATRNLLESMARNVALDALQLPKSWLNGSALLQHMKFSSPFYFSFSRCALSGGHLLQRVIDGGRDLQSLAGLNLSGCAHCLAPDCLLRKAEDDIDPAILEALVAACPNLRHLNLSAAHHHSPAGPSQHLCQLLARLPHLRSLSLPVCAVADSPPRADRAPIPPTMRAVPRGFGKKVRIGVQSVPFPGPAGPQPSSVFWSLLKNVPFLDRLELIGSNFSSAMPRNEPAIRNSLPPCSRAQSVGDAEVAAIGQLAFLRHLTLAQLPSILTGSGLVSIGLQCQQLQSLSLAHLGLMGKVVYMSGLSDMLKHCKRLKDLRLEQPYFSANAQFFQALSQCSALQRLCLVSRSGTLQPEAVLAFMARCLHVVVCHLFTGESLSTCRSLQQALLRSFSGQEASQQVLLRPRSKPALLPG", "length": 683, "header": "tr|A0AAA9T7P6-1|F6PQR5_BOVIN Computationally mapped isoform of F-box and leucine rich repeat protein 18 OS=Bos taurus OX=9913 GN=FBXL18 PE=4 SV=1 CANONICAL=F6PQR5-1" }, "locus": { "chromosome": "25", "start_pos": 38829197, "end_pos": 38810196, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000114225.2", "url": "https://www.ensembl.org/id/ENSBTAT00000114225.2" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000091873.1", "url": "https://www.ensembl.org/id/ENSBTAP00000091873.1" } ] } }, { "isoform_ac": "A0AAA9TY08-1", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TY08/entry", "sequence": { "sequence": "MCWGWTEENAGQLLLCCDTCDDSDTAPVADSAHLLGFSDEILLHILSHVPSTDLVLNVRRTCRKLAALCLDKSLTHTVLLQKDYEASEDKVKRLVKEIGRDVQQLSMAGCYWLSGTTVEHVARCRGLVRVNLSGCPLTSLRLSKVLSALPHLRSLAIDVSPGFDASQLSSECKATLSRVRELKQTLYTPSYGVVPCCTSLEKLLLYFEILDRTREGAVLSGQLMVGQSNVPHYQHLRVFYARLAPGYINQEVVRLYLAVLSDRTPENLHAFLISVPGSFAESGATRNLLESMARNVALDALQLPKSWLNGSALLQHMKFSSPFYFSFSRCALSGGHLLQRVIDGGRDLQSLAGLNLSGCAHCLAPDCLLRKAEDDIDPAILEALVAACPNLRHLNLSAAHHHSPAGPSQHLCQLLARLPHLRSLSLPVCAVADSPPRADRAPIPPTMRAVPRGFGKKVRIGVQSVPFPGPAGPQPSSVFWSLLKNVPFLDRLELIGSNFSSAMPRNEPAIRNSLPPCSRAQSVGDAEVAAIGQLAFLRHLTLAQLPSILTGSGLVSIGLQCQQLQSLSLAHLGLMGKVVYMSGLSDMLKHCKRLKDLRLEQPYFSANAQFFQALSQCSALQRLCLVSRSGTLQPEAVLAFMARCLHVVVCHLFTGESLSTCRSLQQALLRSFQAERPALNVVVFPLLHEGLTDVIRDVPMVHLDEVTLFKSRVAEEPPNLWW", "length": 722, "header": "tr|A0AAA9TY08-1|A0AAA9TY08_BOVIN Computationally mapped isoform of F-box and leucine rich repeat protein 18 OS=Bos taurus OX=9913 GN=FBXL18 PE=4 SV=1 CANONICAL=F6PQR5-1" }, "locus": { "chromosome": "25", "start_pos": 38832322, "end_pos": 38813984, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000112932.2", "url": "https://www.ensembl.org/id/ENSBTAT00000112932.2" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000101542.1", "url": "https://www.ensembl.org/id/ENSBTAP00000101542.1" } ] } }, { "isoform_ac": "F1MNH8-1", "url": "https://www.uniprot.org/uniprotkb/F1MNH8/entry", "sequence": { "sequence": "MASSGEDTCDDSDTAPVADSAHLLGFSDEILLHILSHVPSTDLVLNVRRTCRKLAALCLDKSLTHTVLLQKDYEASEDKVKRLVKEIGRDVQQLSMAGCYWLSGTTVEHVARCRGLVRVNLSGCPLTSLRLSKVLSALPHLRSLAIDVSPGFDASQLSSECKATLSRVRELKQTLYTPSYGVVPCCTSLEKLLLYFEILDRTREGAVLSGQLMVGQSNVPHYQHLRVFYARLAPGYINQEVVRLYLAVLSDRTPENLHAFLISVPGSFAESGATRNLLESMARNVALDALQLPKSWLNGSALLQHMKFSSPFYFSFSRCALSGGHLLQRVIDGGRDLQSLAGLNLSGCAHCLAPDCLLRKAEDDIDPAILEALVAACPNLRHLNLSAAHHHSPAGPSQHLCQLLARLPHLRSLSLPVCAVADSPPRADRAPIPPTMRAVPRGFGKKVRIGVQSVPFPGPAGPQPSSVFWSLLKNVPFLDRLELIGSNFSSAMPRNEPAIRNSLPPCSRAQSVGDAEVAAIGQLAFLRHLTLAQLPSILTGSGLVSIGLQCQQLQSLSLAHLGLMGKVVYMSGLSDMLKHCKRLKDLRLEQPYFSANAQFFQALSQCSALQRLCLVSRSGTLQPEAVLAFMARCLHVVVCHLFTGESLSTCRSLQQALLRRAL", "length": 662, "header": "tr|F1MNH8-1|F6PQR5_BOVIN Computationally mapped isoform of F-box and leucine rich repeat protein 18 OS=Bos taurus OX=9913 GN=FBXL18 PE=4 SV=4 CANONICAL=F6PQR5-1" }, "locus": { "chromosome": "25", "start_pos": 38827161, "end_pos": 38810196, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000043540.5", "url": "https://www.ensembl.org/id/ENSBTAT00000043540.5" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000041104.4", "url": "https://www.ensembl.org/id/ENSBTAP00000041104.4" } ] } }, { "isoform_ac": "F6PQR5-1", "url": "https://www.uniprot.org/uniprotkb/F6PQR5/entry", "sequence": { "sequence": "MASSGEDTCDDSDTAPVADSAHLLGFSDEILLHILSHVPSTDLVLNVRRTCRKLAALCLDKSLTHTVLLQKDYEASEDKVKRLVKEIGRDVQQLSMAGCYWLSGTTVEHVARCRGLVRVNLSGCPLTSLRLSKVLSALPHLRSLAIDVSPGFDASQLSSECKATLSRVRELKQTLYTPSYGVVPCCTSLEKLLLYFEILDRTREGAVLSGQLMVGQSNVPHYQHLRVFYARLAPGYINQEVVRLYLAVLSDRTPENLHAFLISVPGSFAESGATRNLLESMARNVALDALQLPKSWLNGSALLQHMKFSSPFYFSFSRCALSGGHLLQRVIDGGRDLQSLAGLNLSGCAHCLAPDCLLRKAEDDIDPAILEALVAACPNLRHLNLSAAHHHSPAGPSQHLCQLLARLPHLRSLSLPVCAVADSPPRADRAPIPPTMRAVPRGFGKKVRIGVQSVPFPGPAGPQPSSVFWSLLKNVPFLDRLELIGSNFSSAMPRNEPAIRNSLPPCSRAQSVGDAEVAAIGQLAFLRHLTLAQLPSILTGSGLVSIGLQCQQLQSLSLAHLGLMGKVVYMSGLSDMLKHCKRLKDLRLEQPYFSANAQFFQALSQCSALQRLCLVSRSGTLQPEAVLAFMARCLHVVVCHLFTGESLSTCRSLQQALLRSFQAERPALNVVVFPLLHEGLTDVIRDVPMVHLDEVTLFKSRVAEEPPNLWW", "length": 711, "header": "tr|F6PQR5-1|F6PQR5_BOVIN Isoform 1 of F-box and leucine rich repeat protein 18 OS=Bos taurus OX=9913 GN=FBXL18 PE=4 SV=4 CANONICAL=F6PQR5-1" }, "locus": { "chromosome": "25", "start_pos": 38832322, "end_pos": 38810196, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000046646.5", "url": "https://www.ensembl.org/id/ENSBTAT00000046646.5" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000043924.5", "url": "https://www.ensembl.org/id/ENSBTAP00000043924.5" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [ { "id": "bta:789838", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?bta:789838", "resource": "KEGG Pathway" } ], "orthologs": [], "go_annotation": { "categories": [ { "name": "Biological Process", "total": 1, "go_terms": [ { "name": "SCF-dependent proteasomal ubiquitin-dependent protein catabolic process", "id": "GO:0031146", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0031146", "evidence": [ { "database": "UniProtKB", "id": "F6PQR5", "url": "https://www.uniprot.org/uniprotkb/F6PQR5" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 1, "go_terms": [ { "name": "SCF ubiquitin ligase complex", "id": "GO:0019005", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0019005", "evidence": [ { "database": "UniProtKB", "id": "F6PQR5", "url": "https://www.uniprot.org/uniprotkb/F6PQR5" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 120, "end_pos": 122, "annotation": "n_glycosylation_sequon" }, { "start_pos": 298, "end_pos": 300, "annotation": "n_glycosylation_sequon" }, { "start_pos": 344, "end_pos": 346, "annotation": "n_glycosylation_sequon" }, { "start_pos": 384, "end_pos": 386, "annotation": "n_glycosylation_sequon" }, { "start_pos": 487, "end_pos": 489, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "F6PQR5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F6PQR5" }, { "id": "PF12937", "database": "Pfam", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF12937" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "F-box", "eco_id": "ECO_0000259", "start_pos": 28, "end_pos": 69, "start_aa": "Asp", "end_aa": "Leu", "glycosite_overlap": [] }, { "evidence": [ { "id": "F6PQR5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F6PQR5" }, { "id": "PF19729", "database": "Pfam", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF19729" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "F-box/LRR-repeat protein 18 LRR", "eco_id": "ECO_0000259", "start_pos": 80, "end_pos": 668, "start_aa": "Val", "end_aa": "Leu", "glycosite_overlap": [] } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 120, "end_pos": 122 }, { "start_pos": 298, "end_pos": 300 }, { "start_pos": 344, "end_pos": 346 }, { "start_pos": 384, "end_pos": 386 }, { "start_pos": 487, "end_pos": 489 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ], "tool_support": { "graph_view": "yes" } }, { "uniprot_canonical_ac": "F6QE02-1", "uniprot_ac": "F6QE02", "uniprot_id": "F6QE02_BOVIN", "mass": { "chemical_mass": 28299.0, "monoisotopic_mass": 28299.0 }, "refseq": {}, "gene_names": [ { "name": "AP1S3", "type": "recommended", "evidence": [ { "id": "F6QE02", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F6QE02" } ] } ], "protein_names": [ { "name": "Adaptor related protein complex 1 subunit sigma 3", "type": "synonym", "evidence": [ { "id": "F6QE02", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F6QE02/entry#names_and_taxonomy" } ] } ], "function": [], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Bos taurus", "taxid": 9913, "evidence": [ { "database": "UniProtKB", "id": "F6QE02", "url": "https://www.uniprot.org/uniprotkb/F6QE02" } ], "common_name": "Bovine", "glygen_name": "Bovine", "reference_species": "Bos taurus [9913]" } ], "gene": [ { "name": "AP1S3", "url": "https://www.uniprot.org/uniprotkb/F6QE02", "locus": { "chromosome": "2", "start_pos": 111898333, "end_pos": 111965349, "strand": "+", "evidence": [ { "database": "Ensembl Gene", "id": "ENSBTAG00000011133", "url": "https://www.ensembl.org/id/ENSBTAG00000011133" } ] } } ], "crossref": [ { "id": "F6QE02", "url": "https://alphafold.ebi.ac.uk/entry/F6QE02", "database": "AlphaFoldDB", "categories": [] }, { "id": "ENSBTAG00000011133", "url": "https://bgee.org/?page=gene&gene_id=ENSBTAG00000011133", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "cd14831", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd14831", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "IPR000804", "url": "https://www.ebi.ac.uk/interpro/entry/IPR000804", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR011012", "url": "https://www.ebi.ac.uk/interpro/entry/IPR011012", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR016635", "url": "https://www.ebi.ac.uk/interpro/entry/IPR016635", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR022775", "url": "https://www.ebi.ac.uk/interpro/entry/IPR022775", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR044733", "url": "https://www.ebi.ac.uk/interpro/entry/IPR044733", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "A0A3Q1LMK0", "url": "https://www.orthodb.org/?gene=A0A3Q1LMK0", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR11753", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR11753", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF01217", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF01217", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "A0A3Q1LMK0", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1LMK0", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A3Q1LMK0-1", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1LMK0-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0AAA9S137", "url": "https://www.uniprot.org/uniprotkb/A0AAA9S137", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0AAA9S137-1", "url": "https://www.uniprot.org/uniprotkb/A0AAA9S137-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0AAA9SCN6", "url": "https://www.uniprot.org/uniprotkb/A0AAA9SCN6", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0AAA9SCN6-1", "url": "https://www.uniprot.org/uniprotkb/A0AAA9SCN6-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0AAA9SZV0", "url": "https://www.uniprot.org/uniprotkb/A0AAA9SZV0", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0AAA9SZV0-1", "url": "https://www.uniprot.org/uniprotkb/A0AAA9SZV0-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0AAA9T0S3", "url": "https://www.uniprot.org/uniprotkb/A0AAA9T0S3", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0AAA9T0S3-1", "url": "https://www.uniprot.org/uniprotkb/A0AAA9T0S3-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0AAA9T351", "url": "https://www.uniprot.org/uniprotkb/A0AAA9T351", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0AAA9T351-1", "url": "https://www.uniprot.org/uniprotkb/A0AAA9T351-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0AAA9T8S9", "url": "https://www.uniprot.org/uniprotkb/A0AAA9T8S9", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0AAA9T8S9-1", "url": "https://www.uniprot.org/uniprotkb/A0AAA9T8S9-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0AAA9TLE8", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TLE8", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0AAA9TLE8-1", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TLE8-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0ABI0P4C8", "url": "https://www.uniprot.org/uniprotkb/A0ABI0P4C8", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0ABI0P4C8-1", "url": "https://www.uniprot.org/uniprotkb/A0ABI0P4C8-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "F6QE02", "url": "https://www.uniprot.org/uniprotkb/F6QE02", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "F6QE02-1", "url": "https://www.uniprot.org/uniprotkb/F6QE02-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MRKGEEQEEGEEEGKEGGAAGWGRKCGREGARGAGGEGELRRGAEPANFRFEGIVGSSHGLMWAPHLSAAPAPALASRPRVPRARPSPAGDGGGPATMIHFILLFSRQGKLRLQKWYTTLPDKERKKITREIVQIILSRGQRTSSFVDWKELKLVYKRYASLYFCCAVENQDNELLTLEIVHRYVELLDKYFGNVCELDIIFNFEKAYFILDEFIIGGEIQETSKKSAVKAIEDSDMLQETMEEYMNKPTF", "length": 251, "header": "tr|F6QE02-1|F6QE02_BOVIN Isoform 1 of Adaptor related protein complex 1 subunit sigma 3 OS=Bos taurus OX=9913 GN=AP1S3 PE=3 SV=1 CANONICAL=F6QE02-1" }, "isoforms": [ { "isoform_ac": "A0A3Q1LMK0-1", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1LMK0/entry", "sequence": { "sequence": "MIHFILLFSRQGKLRLQKWYTTLPDKERKKITREIVQIILSRGQRTSSFVDWKELKLVYKRYASLYFCCAVENQDNELLTLEIVHRYVELLDKYFGNVCELDIIFNFEKAYFILDEFIIGGEIQETSKKSAVKAIEDSDMLQEVSTFSHALGRR", "length": 154, "header": "tr|A0A3Q1LMK0-1|A0A3Q1LMK0_BOVIN Computationally mapped isoform of AP complex subunit sigma OS=Bos taurus OX=9913 GN=AP1S3 PE=3 SV=2 CANONICAL=F6QE02-1" }, "locus": { "chromosome": "2", "start_pos": 111965037, "end_pos": 111906199, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000079279.2", "url": "https://www.ensembl.org/id/ENSBTAT00000079279.2" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000057937.2", "url": "https://www.ensembl.org/id/ENSBTAP00000057937.2" } ] } }, { "isoform_ac": "A0AAA9S137-1", "url": "https://www.uniprot.org/uniprotkb/A0AAA9S137/entry", "sequence": { "sequence": "MEISGLLEVVKAQKIHFILLFSRQGKLRLQKWYTTLPDKERKKITREIVQIILSRGQRTSSFVDWKELKLVYKRYASLYFCCAVENQDNELLTLEIVHRYVELLDKYFGNVCELDIIFNFEKAYFILDEFIIGGEIQETSKKSAVKAIEDSDMLQETMEEYMNKPTF", "length": 167, "header": "tr|A0AAA9S137-1|F6QE02_BOVIN Computationally mapped isoform of Adaptor related protein complex 1 subunit sigma 3 OS=Bos taurus OX=9913 GN=AP1S3 PE=3 SV=1 CANONICAL=F6QE02-1" }, "locus": { "chromosome": "2", "start_pos": 111937330, "end_pos": 111900220, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000100793.1", "url": "https://www.ensembl.org/id/ENSBTAT00000100793.1" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000079585.1", "url": "https://www.ensembl.org/id/ENSBTAP00000079585.1" } ] } }, { "isoform_ac": "A0AAA9SCN6-1", "url": "https://www.uniprot.org/uniprotkb/A0AAA9SCN6/entry", "sequence": { "sequence": "MIHFILLFSRQGKLRLQKWYTTLPDKERKKITREIVQIILSRGQRTSSFVDWKELKLVYKRYASLYFCCAVENQDNELLTLEIVHRYVELLDKYFGNDSGCWFLLMRFLSVLDSWSTPALNSGVPQLATVTPDSRLF", "length": 137, "header": "tr|A0AAA9SCN6-1|F6QE02_BOVIN Computationally mapped isoform of Adaptor related protein complex 1 subunit sigma 3 OS=Bos taurus OX=9913 GN=AP1S3 PE=3 SV=2 CANONICAL=F6QE02-1" }, "locus": { "chromosome": "2", "start_pos": 111965037, "end_pos": 111910672, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000105809.2", "url": "https://www.ensembl.org/id/ENSBTAT00000105809.2" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000081632.2", "url": "https://www.ensembl.org/id/ENSBTAP00000081632.2" } ] } }, { "isoform_ac": "A0AAA9SZV0-1", "url": "https://www.uniprot.org/uniprotkb/A0AAA9SZV0/entry", "sequence": { "sequence": "GGTKVTCGLQTVIHFILLFSRQGKLRLQKWYTTLPDKERKKITREIVQIILSRGQRTSSFVDWKELKLVYKRYASLYFCCAVENQDNELLTLEIVHRYVELLDKYFGNVCELDIIFNFEKAYFILDEFIIGGEIQETSKKSAVKAIEDSDMLQETMEEYMNKPTF", "length": 165, "header": "tr|A0AAA9SZV0-1|F6QE02_BOVIN Computationally mapped isoform of Adaptor related protein complex 1 subunit sigma 3 OS=Bos taurus OX=9913 GN=AP1S3 PE=3 SV=1 CANONICAL=F6QE02-1" }, "locus": { "chromosome": "2", "start_pos": 111958310, "end_pos": 111900220, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000115019.1", "url": "https://www.ensembl.org/id/ENSBTAT00000115019.1" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000090949.1", "url": "https://www.ensembl.org/id/ENSBTAP00000090949.1" } ] } }, { "isoform_ac": "A0AAA9T0S3-1", "url": "https://www.uniprot.org/uniprotkb/A0AAA9T0S3/entry", "sequence": { "sequence": "RKSLVSFDLQIHFILLFSRQGKLRLQKWYTTLPDKERKKITREIVQIILSRGQRTSSFVDWKELKLVYKRYASLYFCCAVENQDNELLTLEIVHRYVELLDKYFGNVCELDIIFNFEKAYFILDEFIIGGEIQETSKKSAVKAIEDSDMLQETMEEYMNKPTF", "length": 163, "header": "tr|A0AAA9T0S3-1|F6QE02_BOVIN Computationally mapped isoform of Adaptor related protein complex 1 subunit sigma 3 OS=Bos taurus OX=9913 GN=AP1S3 PE=3 SV=1 CANONICAL=F6QE02-1" }, "locus": { "chromosome": "2", "start_pos": 111919219, "end_pos": 111900220, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000132726.1", "url": "https://www.ensembl.org/id/ENSBTAT00000132726.1" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000091286.1", "url": "https://www.ensembl.org/id/ENSBTAP00000091286.1" } ] } }, { "isoform_ac": "A0AAA9T351-1", "url": "https://www.uniprot.org/uniprotkb/A0AAA9T351/entry", "sequence": { "sequence": "GVWILFQPSGRGPVIQIHFILLFSRQGKLRLQKWYTTLPDKERKKITREIVQIILSRGQRTSSFVDWKELKLVYKRYASLYFCCAVENQDNELLTLEIVHRYVELLDKYFGNVCELDIIFNFEKAYFILDEFIIGGEIQETSKKSAVKAIEDSDMLQETMEEYMNKPTF", "length": 169, "header": "tr|A0AAA9T351-1|F6QE02_BOVIN Computationally mapped isoform of Adaptor related protein complex 1 subunit sigma 3 OS=Bos taurus OX=9913 GN=AP1S3 PE=3 SV=1 CANONICAL=F6QE02-1" }, "locus": { "chromosome": "2", "start_pos": 111964425, "end_pos": 111900220, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000103320.1", "url": "https://www.ensembl.org/id/ENSBTAT00000103320.1" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000090114.1", "url": "https://www.ensembl.org/id/ENSBTAP00000090114.1" } ] } }, { "isoform_ac": "A0AAA9T8S9-1", "url": "https://www.uniprot.org/uniprotkb/A0AAA9T8S9/entry", "sequence": { "sequence": "QIHFILLFSRQGKLRLQKWYTTLPDKERKKITREIVQIILSRGQRTSSFVDWKELKLVYKRYASLYFCCAVENQDNELLTLEIVHRYVELLDKYFGNVCELDIIFNFEKAYFILDEFIIGGEIQETSKKSAVKAIEDSDMLQETMEEYMNKPTF", "length": 154, "header": "tr|A0AAA9T8S9-1|F6QE02_BOVIN Computationally mapped isoform of Adaptor related protein complex 1 subunit sigma 3 OS=Bos taurus OX=9913 GN=AP1S3 PE=3 SV=1 CANONICAL=F6QE02-1" }, "locus": { "chromosome": "2", "start_pos": 111921333, "end_pos": 111900220, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000088340.1", "url": "https://www.ensembl.org/id/ENSBTAT00000088340.1" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000094379.1", "url": "https://www.ensembl.org/id/ENSBTAP00000094379.1" } ] } }, { "isoform_ac": "A0AAA9TLE8-1", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TLE8/entry", "sequence": { "sequence": "LPRIHFILLFSRQGKLRLQKWYTTLPDKERKKITREIVQIILSRGQRTSSFVDWKELKLVYKRYASLYFCCAVENQDNELLTLEIVHRYVELLDKYFGNVCELDIIFNFEKAYFILDEFIIGGEIQETSKKSAVKAIEDSDMLQETMEEYMNKPTF", "length": 156, "header": "tr|A0AAA9TLE8-1|F6QE02_BOVIN Computationally mapped isoform of Adaptor related protein complex 1 subunit sigma 3 OS=Bos taurus OX=9913 GN=AP1S3 PE=3 SV=1 CANONICAL=F6QE02-1" }, "locus": { "chromosome": "2", "start_pos": 111964668, "end_pos": 111900220, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000135445.1", "url": "https://www.ensembl.org/id/ENSBTAT00000135445.1" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000097762.1", "url": "https://www.ensembl.org/id/ENSBTAP00000097762.1" } ] } }, { "isoform_ac": "A0ABI0P4C8-1", "url": "https://www.uniprot.org/uniprotkb/A0ABI0P4C8/entry", "sequence": { "sequence": "MIHFILLFSRQGKLRLQKWYTTLPDKERKKITREIVQIILSRGQRTSSFVDWKELKLVYKRCL", "length": 63, "header": "tr|A0ABI0P4C8-1|A0ABI0P4C8_BOVIN Computationally mapped isoform of Adaptor related protein complex 1 subunit sigma 3 OS=Bos taurus OX=9913 GN=AP1S3 PE=3 SV=1 CANONICAL=F6QE02-1" }, "locus": { "chromosome": "2", "start_pos": 111965037, "end_pos": 111906369, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000142344.1", "url": "https://www.ensembl.org/id/ENSBTAT00000142344.1" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000105594.1", "url": "https://www.ensembl.org/id/ENSBTAP00000105594.1" } ] } }, { "isoform_ac": "F6QE02-1", "url": "https://www.uniprot.org/uniprotkb/F6QE02/entry", "sequence": { "sequence": "MRKGEEQEEGEEEGKEGGAAGWGRKCGREGARGAGGEGELRRGAEPANFRFEGIVGSSHGLMWAPHLSAAPAPALASRPRVPRARPSPAGDGGGPATMIHFILLFSRQGKLRLQKWYTTLPDKERKKITREIVQIILSRGQRTSSFVDWKELKLVYKRYASLYFCCAVENQDNELLTLEIVHRYVELLDKYFGNVCELDIIFNFEKAYFILDEFIIGGEIQETSKKSAVKAIEDSDMLQETMEEYMNKPTF", "length": 251, "header": "tr|F6QE02-1|F6QE02_BOVIN Isoform 1 of Adaptor related protein complex 1 subunit sigma 3 OS=Bos taurus OX=9913 GN=AP1S3 PE=3 SV=1 CANONICAL=F6QE02-1" }, "locus": { "chromosome": "2", "start_pos": 111965328, "end_pos": 111900220, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000014784.6", "url": "https://www.ensembl.org/id/ENSBTAT00000014784.6" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000014784.5", "url": "https://www.ensembl.org/id/ENSBTAP00000014784.5" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [], "orthologs": [], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 4, "go_terms": [ { "name": "clathrin-coated pit", "id": "GO:0005905", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005905", "evidence": [ { "database": "UniProtKB", "id": "F6QE02", "url": "https://www.uniprot.org/uniprotkb/F6QE02" } ], "pmid": "" }, { "name": "AP-1 adaptor complex", "id": "GO:0030121", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030121", "evidence": [ { "database": "UniProtKB", "id": "F6QE02", "url": "https://www.uniprot.org/uniprotkb/F6QE02" } ], "pmid": "" }, { "name": "endomembrane system", "id": "GO:0012505", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0012505", "evidence": [ { "database": "UniProtKB", "id": "F6QE02", "url": "https://www.uniprot.org/uniprotkb/F6QE02" } ], "pmid": "" }, { "name": "membrane coat", "id": "GO:0030117", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030117", "evidence": [ { "database": "UniProtKB", "id": "F6QE02", "url": "https://www.uniprot.org/uniprotkb/F6QE02" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 3, "go_terms": [ { "name": "intracellular protein transport", "id": "GO:0006886", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006886", "evidence": [ { "database": "UniProtKB", "id": "F6QE02", "url": "https://www.uniprot.org/uniprotkb/F6QE02" } ], "pmid": "" }, { "name": "vesicle-mediated transport", "id": "GO:0016192", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016192", "evidence": [ { "database": "UniProtKB", "id": "F6QE02", "url": "https://www.uniprot.org/uniprotkb/F6QE02" } ], "pmid": "" }, { "name": "protein transport", "id": "GO:0015031", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0015031", "evidence": [ { "database": "UniProtKB", "id": "F6QE02", "url": "https://www.uniprot.org/uniprotkb/F6QE02" } ], "pmid": "" } ] }, { "name": "Molecular Function", "total": 1, "go_terms": [ { "name": "clathrin adaptor activity", "id": "GO:0035615", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0035615", "evidence": [ { "database": "UniProtKB", "id": "F6QE02", "url": "https://www.uniprot.org/uniprotkb/F6QE02" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "F6QE02", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F6QE02" }, { "id": "PF01217", "database": "Pfam", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF01217" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "AP complex mu/sigma subunit", "eco_id": "ECO_0000259", "start_pos": 98, "end_pos": 237, "start_aa": "Met", "end_aa": "Met", "glycosite_overlap": [] } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", 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"Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF00620", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00620", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "A0AAA9S1I1", "url": "https://www.uniprot.org/uniprotkb/A0AAA9S1I1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0AAA9S1I1-1", "url": "https://www.uniprot.org/uniprotkb/A0AAA9S1I1-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0AAA9T080", "url": "https://www.uniprot.org/uniprotkb/A0AAA9T080", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0AAA9T080-1", "url": "https://www.uniprot.org/uniprotkb/A0AAA9T080-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0AAA9TJP8", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TJP8", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0AAA9TJP8-1", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TJP8-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0AAA9TYJ8", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TYJ8", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0AAA9TYJ8-1", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TYJ8-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "F6R1C7", "url": "https://www.uniprot.org/uniprotkb/F6R1C7", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "F6R1C7-1", "url": "https://www.uniprot.org/uniprotkb/F6R1C7-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MSLKLPRNWDFNLRGEAGKIARSRSVMTGEQMAAFHPASTPNPLERPIKMGWLKKQRSIVRNWQQRYFVLRAQQLYYYKDEEDVKPQGCMYLPGSTIKEIATNPEEAGKFVFEVIPASCDQSRTGQDSYVLMASSQAEMEEWVKFLRRVSGTPSGAVFGQRLDETVAYEQKFGPHLVPILVEKCAEFILEHGLNEEGIFRLPGQDNLVKQLRDAFDAGERPSFDRDTDVHTVASLLKLYLRDLPEPVVPWSQYDGFLLCGQLMNSDEAKPQLPAGPTVPVCNITKLFTSRSFDPQAQQELIKQLSILPRENYSLLSYICRFLHEIQLNCGVNKMSVDNLATVIGVNLIRSKVEDPAVIMRGTPQIQRVMTMMIRDHEVLFPKSKDAPLSPPAPQNDPKKPPVARSSVGWDATEDPPISRTDSASDSDATSPTGQQPNDGCLEDKASRDKPGDWKPQSRKRTQTLPNRKCFLTSALQGANSCKTEIFKNEFWSSSSEAKAGDGHRRTMSQGVPQLFDSQRTSTYDNVPTQPGSPGDKASTLSPQACDSKRDALASLNSETGPGKKISGEEELESLQRMVQELRKEIETQKQMYEEQIENLEKENYDVWAKVVRLNEELENEKKKSAALEISLRNVERCREDVEKRNKVLEEEVKEFVKSIKEPKTDA", "length": 666, "header": "tr|F6R1C7-1|F6R1C7_BOVIN Isoform 1 of Rho GTPase activating protein 25 OS=Bos taurus OX=9913 GN=ARHGAP25 PE=4 SV=1 CANONICAL=F6R1C7-1" }, "isoforms": [ { "isoform_ac": "A0AAA9S1I1-1", "url": "https://www.uniprot.org/uniprotkb/A0AAA9S1I1/entry", "sequence": { "sequence": "MQSGGCEMCSWLSQVQRNPAPLGWLEARSRSVMTGEQMAAFHPASTPNPLERPIKMGWLKKQRSIVRNWQQRYFVLRAQQLYYYKDEEDVKPQGCMYLPGSTIKEIATNPEEAGKFVFEVIPASCDQSRTGQDSYVLMASSQAEMEEWVKFLRRVSGTPSGAVFGQRLDETVAYEQKFGPHLVPILVEKCAEFILEHGLNEEGIFRLPGQDNLVKQLRDAFDAGERPSFDRDTDVHTVASLLKLYLRDLPEPVVPWSQYDGFLLCGQLMNSDEAKAQQELIKQLSILPRENYSLLSYICRFLHEIQLNCGVNKMSVDNLATVIGVNLIRSKVEDPAVIMRGTPQIQRVMTMMIRDHEVLFPKSKDAPLSPPAPQNDPKKPPVARSSVGWDATEDPPISRTDSASDSDATSPTGQQPNDGCLEDKASRDKPGDWKPQSRKRTQTLPNRKCFLTSALQGANSCKTEIFKNEFWSSSSEAKAGDGHRRTMSQGVPQLFDSQRTSTYDNVPTQPGSPGDKASTLSPQACDSKRDALASLNSETGPGKKISGEEELESLQRMVQELRKEIETQKQMYEEQIENLEKENYDVWAKVVRLNEELENEKKKSAALEISLRNVERCREDVEKRNKVLEEEVKEFVKSIKEPKTDA", "length": 646, "header": "tr|A0AAA9S1I1-1|F6R1C7_BOVIN Computationally mapped isoform of Rho GTPase activating protein 25 OS=Bos taurus OX=9913 GN=ARHGAP25 PE=4 SV=1 CANONICAL=F6R1C7-1" }, "locus": { "chromosome": "11", "start_pos": 67182827, "end_pos": 67088797, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000097381.2", "url": "https://www.ensembl.org/id/ENSBTAT00000097381.2" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000079735.1", "url": "https://www.ensembl.org/id/ENSBTAP00000079735.1" } ] } }, { "isoform_ac": "A0AAA9T080-1", "url": "https://www.uniprot.org/uniprotkb/A0AAA9T080/entry", "sequence": { "sequence": "MELLGMWDLGYLAWTKATDLTKHARSRSVMTGEQMAAFHPASTPNPLERPIKMGWLKKQRSIVRNWQQRYFVLRAQQLYYYKDEEDVKPQGCMYLPGSTIKEIATNPEEAGKFVFEVIPASCDQSRTGQDSYVLMASSQAEMEEWVKFLRRVSGTPSGAVFGQRLDETVAYEQKFGPHLVPILVEKCAEFILEHGLNEEGIFRLPGQDNLVKQLRDAFDAGERPSFDRDTDVHTVASLLKLYLRDLPEPVVPWSQYDGFLLCGQLMNSDEAKAQQELIKQLSILPRENYSLLSYICRFLHEIQLNCGVNKMSVDNLATVIGVNLIRSKVEDPAVIMRGTPQIQRVMTMMIRDHEVLFPKSKDAPLSPPAPQNDPKKPPVARSSVGWDATEDPPISRTDSASDSDATSPTGQQPNDGCLEDKASRDKPGDWKPQSRKRTQTLPNRKCFLTSALQGANSCKTEIFKNEFWSSSSEAKAGDGHRRTMSQGVPQLFDSQRTSTYDNVPTQPGSPGDKASTLSPQACDSKRDALASLNSETGPGKKISGEEELESLQRMVQELRKEIETQKQMYEEQIENLEKENYDVWAKVVRLNEELENEKKKSAALEISLRNVERCREDVEKRNKVLEEEVKEFVKSIKEPKTDA", "length": 643, "header": "tr|A0AAA9T080-1|F6R1C7_BOVIN Computationally mapped isoform of Rho GTPase activating protein 25 OS=Bos taurus OX=9913 GN=ARHGAP25 PE=4 SV=2 CANONICAL=F6R1C7-1" }, "locus": { "chromosome": "11", "start_pos": 67182827, "end_pos": 67091772, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000124072.2", "url": "https://www.ensembl.org/id/ENSBTAT00000124072.2" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000092153.2", "url": "https://www.ensembl.org/id/ENSBTAP00000092153.2" } ] } }, { "isoform_ac": "A0AAA9TJP8-1", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TJP8/entry", "sequence": { "sequence": "MSLKLPRNWDFNLRGEAGKIARSRSVMTGEQMAAFHPASTPNPLERPIKMGWLKKQRSIVRNWQQRYFVLRAQQLYYYKDEEDVKPQGCMYLPGSTIKEIATNPEEAGKFVFEVIPAVFGQRLDETVAYEQKFGPHLVPILVEKCAEFILEHGLNEEGIFRLPGQDNLVKQLRDAFDAGERPSFDRDTDVHTVASLLKLYLRDLPEPVVPWSQYDGFLLCGQLMNSDEAKAQQELIKQLSILPRENYSLLSYICRFLHEIQLNCGVNKMSVDNLATVIGVNLIRSKVEDPAVIMRGTPQIQRVMTMMIRDHEVLFPKSKDAPLSPPAPQNDPKKPPVARSSVGWDATEDPPISRTDSASDSDATSPTGQQPNDGCLEDKASRDKPGDWKPQSRKRTQTLPNRKCFLTSALQGANSCKTEIFKNEFWSSSSEAKAGDGHRRTMSQGVPQLFDSQRTSTYDNVPTQPGSPGDKASTLSPQACDSKRDALASLNSETGPGKKISGEEELESLQRMVQELRKEIETQKQMYEEQIENLEKENYDVWAKVVRLNEELENEKKKSAALEISLRNVERCREDVEKRNKVLEEEVKEFVKSIKEPKTDA", "length": 601, "header": "tr|A0AAA9TJP8-1|F6R1C7_BOVIN Computationally mapped isoform of Rho GTPase activating protein 25 OS=Bos taurus OX=9913 GN=ARHGAP25 PE=4 SV=1 CANONICAL=F6R1C7-1" }, "locus": { "chromosome": "11", "start_pos": 67182827, "end_pos": 67091495, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000121459.2", "url": "https://www.ensembl.org/id/ENSBTAT00000121459.2" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000098688.1", "url": "https://www.ensembl.org/id/ENSBTAP00000098688.1" } ] } }, { "isoform_ac": "A0AAA9TYJ8-1", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TYJ8/entry", "sequence": { "sequence": "MDRNAARSRSVMTGEQMAAFHPASTPNPLERPIKMGWLKKQRSIVRNWQQRYFVLRAQQLYYYKDEEDVKPQGCMYLPGSTIKEIATNPEEAGKFVFEVIPASCDQSRTGQDSYVLMASSQAEMEEWVKFLRRVSGTPSGAVFGQRLDETVAYEQKFGPHLVPILVEKCAEFILEHGLNEEGIFRLPGQDNLVKQLRDAFDAGERPSFDRDTDVHTVASLLKLYLRDLPEPVVPWSQYDGFLLCGQLMNSDEAKAQQELIKQLSILPRENYSLLSYICRFLHEIQLNCGVNKMSVDNLATVIGVNLIRSKVEDPAVIMRGTPQIQRVMTMMIRDHEVLFPKSKDAPLSPPAPQNDPKKPPVARSSVGWDATEDPPISRTDSASDSDATSPTGQQPNDGCLEDKASRDKPGDWKPQSRKRTQTLPNRKCFLTSALQGANSCKTEIFKNEFWSSSSEAKAGDGHRRTMSQGVPQLFDSQRTSTYDNVPTQPGSPGDKASTLSPQACDSKRDALASLNSETGPGKKISGEEELESLQRMVQELRKEIETQKQMYEEQIENLEKENYDVWAKVVRLNEELENEKKKSAALEISLRNVERCREDVEKRNKVLEEEVKEFVKSIKEPKTDA", "length": 625, "header": "tr|A0AAA9TYJ8-1|A0AAA9TYJ8_BOVIN Computationally mapped isoform of Rho GTPase activating protein 25 OS=Bos taurus OX=9913 GN=ARHGAP25 PE=4 SV=1 CANONICAL=F6R1C7-1" }, "locus": { "chromosome": "11", "start_pos": 67182827, "end_pos": 67113935, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000124348.2", "url": "https://www.ensembl.org/id/ENSBTAT00000124348.2" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000102309.1", "url": "https://www.ensembl.org/id/ENSBTAP00000102309.1" } ] } }, { "isoform_ac": "F6R1C7-1", "url": "https://www.uniprot.org/uniprotkb/F6R1C7/entry", "sequence": { "sequence": "MSLKLPRNWDFNLRGEAGKIARSRSVMTGEQMAAFHPASTPNPLERPIKMGWLKKQRSIVRNWQQRYFVLRAQQLYYYKDEEDVKPQGCMYLPGSTIKEIATNPEEAGKFVFEVIPASCDQSRTGQDSYVLMASSQAEMEEWVKFLRRVSGTPSGAVFGQRLDETVAYEQKFGPHLVPILVEKCAEFILEHGLNEEGIFRLPGQDNLVKQLRDAFDAGERPSFDRDTDVHTVASLLKLYLRDLPEPVVPWSQYDGFLLCGQLMNSDEAKPQLPAGPTVPVCNITKLFTSRSFDPQAQQELIKQLSILPRENYSLLSYICRFLHEIQLNCGVNKMSVDNLATVIGVNLIRSKVEDPAVIMRGTPQIQRVMTMMIRDHEVLFPKSKDAPLSPPAPQNDPKKPPVARSSVGWDATEDPPISRTDSASDSDATSPTGQQPNDGCLEDKASRDKPGDWKPQSRKRTQTLPNRKCFLTSALQGANSCKTEIFKNEFWSSSSEAKAGDGHRRTMSQGVPQLFDSQRTSTYDNVPTQPGSPGDKASTLSPQACDSKRDALASLNSETGPGKKISGEEELESLQRMVQELRKEIETQKQMYEEQIENLEKENYDVWAKVVRLNEELENEKKKSAALEISLRNVERCREDVEKRNKVLEEEVKEFVKSIKEPKTDA", "length": 666, "header": "tr|F6R1C7-1|F6R1C7_BOVIN Isoform 1 of Rho GTPase activating protein 25 OS=Bos taurus OX=9913 GN=ARHGAP25 PE=4 SV=1 CANONICAL=F6R1C7-1" }, "locus": { "chromosome": "11", "start_pos": 67182827, "end_pos": 67091495, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000033004.7", "url": "https://www.ensembl.org/id/ENSBTAT00000033004.7" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000032931.5", "url": "https://www.ensembl.org/id/ENSBTAP00000032931.5" } ] } } ], "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "other", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 277, "start_aa": "Thr", "end_pos": 277, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr277", "evidence": [ { "id": "", "database": "GlyGen", "url": "https://data.glygen.org/" } ], "filter_code": "000000000000000010000.00000000001000.0.01000" } ], "phosphorylation": [], "glycation": [], "keywords": [ "glycoprotein", "glycoprotein_predicted" ], "publication": [], "pathway": [], "orthologs": [], "go_annotation": { "categories": [ { "name": "Molecular Function", "total": 1, "go_terms": [ { "name": "GTPase activator activity", "id": "GO:0005096", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005096", "evidence": [ { "database": "UniProtKB", "id": "F6R1C7", "url": "https://www.uniprot.org/uniprotkb/F6R1C7" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 5, "go_terms": [ { "name": "signal transduction", "id": "GO:0007165", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007165", "evidence": [ { "database": "UniProtKB", "id": "F6R1C7", "url": "https://www.uniprot.org/uniprotkb/F6R1C7" } ], "pmid": "" }, { "name": "regulation of small GTPase mediated signal transduction", "id": "GO:0051056", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0051056", "evidence": [ { "database": "UniProtKB", "id": "F6R1C7", "url": "https://www.uniprot.org/uniprotkb/F6R1C7" } ], "pmid": "" }, { "name": "phagocytosis, engulfment", "id": "GO:0006911", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006911", "evidence": [ { "database": "UniProtKB", "id": "F6R1C7", "url": "https://www.uniprot.org/uniprotkb/F6R1C7" } ], "pmid": "" }, { "name": "actin filament organization", "id": "GO:0007015", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007015", "evidence": [ { "database": "UniProtKB", "id": "F6R1C7", "url": "https://www.uniprot.org/uniprotkb/F6R1C7" } ], "pmid": "" }, { "name": "negative regulation of small GTPase mediated signal transduction", "id": "GO:0051058", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0051058", "evidence": [ { "database": "UniProtKB", "id": "F6R1C7", "url": "https://www.uniprot.org/uniprotkb/F6R1C7" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 1, "go_terms": [ { "name": "phagocytic cup", "id": "GO:0001891", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0001891", "evidence": [ { "database": "UniProtKB", "id": "F6R1C7", "url": "https://www.uniprot.org/uniprotkb/F6R1C7" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 282, "end_pos": 284, "annotation": "n_glycosylation_sequon" }, { "start_pos": 311, "end_pos": 313, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "F6R1C7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F6R1C7" }, { "id": "PS50003", "database": "PROSITE", "url": "https://prosite.expasy.org/PS50003" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "PH", "eco_id": "ECO_0000259", "start_pos": 46, "end_pos": 151, "start_aa": "Arg", "end_aa": "Gly", "glycosite_overlap": [] }, { "evidence": [ { "id": "F6R1C7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F6R1C7" }, { "id": "PS50238", "database": "PROSITE", "url": "https://prosite.expasy.org/PS50238" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "Rho-GAP", "eco_id": "ECO_0000259", "start_pos": 160, "end_pos": 380, "start_aa": "Gln", "end_aa": "Phe", "glycosite_overlap": [] } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [ 277 ], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 282, "end_pos": 284 }, { "start_pos": 311, "end_pos": 313 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 1 }, { "field": "total_sites", "count": 1 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 1 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "exact_sites", "count": 1 }, { "field": 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"Protein Classification" ] }, { "id": "PTHR14949:SF27", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR14949:SF27", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF07546", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF07546", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF07645", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF07645", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "A0AAA9S2G2", "url": "https://www.uniprot.org/uniprotkb/A0AAA9S2G2", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0AAA9S2G2-1", "url": "https://www.uniprot.org/uniprotkb/A0AAA9S2G2-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0AAA9TSB2", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TSB2", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0AAA9TSB2-1", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TSB2-1", 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taurus OX=9913 GN=EGFL8 PE=4 SV=1 CANONICAL=F6QRL7-1" }, "isoforms": [ { "isoform_ac": "A0AAA9S2G2-1", "url": "https://www.uniprot.org/uniprotkb/A0AAA9S2G2/entry", "sequence": { "sequence": "CAKGCQGVCSKQTLVVPLRYNESYSQPVYKPYLTLCSGRRVCSTYRTTYRVAWREVRREVRQTHAVCCQGWKKRHPGALTCDEAICAKPCQNGGVCVRPDQCECARGWGGKHCHVDVDECRTGVTLCSHRCLNTAGSFTCGCPHGLVLGLDGRTCAERAPEPPTSASILNVAVREAGLDKRALRREIGELRGRLERLEQWAGQAGAWVRAVLPVPPEELQPEQVAELWGQGDRIESLSDQVLLLEERLGTCSCEDNSLGPGLKGRR", "length": 266, "header": "tr|A0AAA9S2G2-1|F6QRL7_BOVIN Computationally mapped isoform of Epidermal growth factor-like protein 8 OS=Bos taurus OX=9913 GN=EGFL8 PE=4 SV=1 CANONICAL=F6QRL7-1" }, "locus": { "chromosome": "23", "start_pos": 27223898, "end_pos": 27221860, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000119425.1", "url": "https://www.ensembl.org/id/ENSBTAT00000119425.1" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000080099.1", "url": 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}, { "isoform_ac": "A0AAA9TUP0-1", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TUP0/entry", "sequence": { "sequence": "SLPEKGKDSQGVCSKQTLVVPLRYNESYSQPVYKPYLTLCSGRRVCSTYRTTYRVAWREVRREVRQTHAVCCQGWKKRHPGALTCDEAICAKPCQNGGVCVRPDQCECARGWGGKHCHVDVDECRTGVTLCSHRCLNTAGSFTCGCPHGLVLGLDGRTCAERAPEPPTSASILNVAVREAGLDKRALRREIGELRGRLERLEQWAGQAGAWVRAVLPVPPEELQPEQVAELWGQGDRIESLSDQVLLLEERLGTCSCEDNSLGPGLKGRR", "length": 270, "header": "tr|A0AAA9TUP0-1|F6QRL7_BOVIN Computationally mapped isoform of Epidermal growth factor-like protein 8 OS=Bos taurus OX=9913 GN=EGFL8 PE=4 SV=1 CANONICAL=F6QRL7-1" }, "locus": { "chromosome": "23", "start_pos": 27224245, "end_pos": 27221860, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000124799.1", "url": "https://www.ensembl.org/id/ENSBTAT00000124799.1" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000101059.1", "url": "https://www.ensembl.org/id/ENSBTAP00000101059.1" } ] } }, { "isoform_ac": "F6QRL7-1", "url": "https://www.uniprot.org/uniprotkb/F6QRL7/entry", "sequence": { "sequence": "MSMGKEWGSLRVLDQGVCSKQTLVVPLRYNESYSQPVYKPYLTLCSGRRVCSTYRTTYRVAWREVRREVRQTHAVCCQGWKKRHPGALTCDEAICAKPCQNGGVCVRPDQCECARGWGGKHCHVDVDECRTGVTLCSHRCLNTAGSFTCGCPHGLVLGLDGRTCAERAPEPPTSASILNVAVREAGLDKRALRREIGELRGRLERLEQWAGQAGAWVRAVLPVPPEELQPEQVAELWGQGDRIESLSDQVLLLEERLGTCSCEDNSLGPGLKGRR", "length": 275, "header": "tr|F6QRL7-1|F6QRL7_BOVIN Isoform 1 of Epidermal growth factor-like protein 8 OS=Bos taurus OX=9913 GN=EGFL8 PE=4 SV=1 CANONICAL=F6QRL7-1" }, "locus": { "chromosome": "23", "start_pos": 27224208, "end_pos": 27221860, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000005817.6", "url": "https://www.ensembl.org/id/ENSBTAT00000005817.6" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000005817.5", "url": "https://www.ensembl.org/id/ENSBTAP00000005817.5" } ] } } ], "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "other", "prediction_tool_list": [ { "label": 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"database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F6QRL7" }, { "id": "PS51041", "database": "PROSITE", "url": "https://prosite.expasy.org/PS51041" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "EMI", "eco_id": "ECO_0000259", "start_pos": 14, "end_pos": 92, "start_aa": "Asp", "end_aa": "Glu", "glycosite_overlap": [] } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [ 173 ], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 30, "end_pos": 32 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 1 }, { "field": "total_sites", "count": 1 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 1 }, { "field": 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"sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_pos", "start_aa", "end_pos", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": 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"https://www.ncbi.nlm.nih.gov/protein/NP_001421971" } ] } ], "protein_names": [ { "name": "Outer dense fiber protein 4", "type": "recommended", "evidence": [ { "id": "F1N363", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1N363/entry#names_and_taxonomy" } ] }, { "name": "Outer dense fiber of sperm tails protein 4", "type": "synonym", "evidence": [ { "id": "F1N363", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1N363/entry#names_and_taxonomy" } ] }, { "name": "outer dense fiber of sperm tails protein 4", "type": "synonym", "evidence": [ { "id": "NP_001421971", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001421971" } ] }, { "name": "outer dense fiber protein 4", "type": "synonym", "evidence": [ { "id": "NP_001421971", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001421971" } ] } ], "function": [ { "annotation": "Component of the outer dense fibers (ODF) of spermatozoa which could be involved in sperm tail structure, sperm movement and general organization of cellular cytoskeleton.", "evidence": [ { "database": "UniProtKB", "id": "F1N363", "url": "https://www.uniprot.org/uniprotkb/F1N363#function" }, { "database": "UniProtKB", "id": "ARBA00054558", "url": "https://www.uniprot.org/uniprotkb/ARBA00054558#function" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Bos taurus", "taxid": 9913, "evidence": [ { "database": "UniProtKB", "id": "F1N363", "url": "https://www.uniprot.org/uniprotkb/F1N363" } ], "common_name": "Bovine", "glygen_name": "Bovine", "reference_species": "Bos taurus [9913]" } ], "gene": [ { "name": "ODF4", "url": "https://www.uniprot.org/uniprotkb/F1N363", "locus": { "chromosome": "19", "start_pos": 27955495, "end_pos": 27949539, "strand": "-", "evidence": [ { "database": "Ensembl Gene", "id": "ENSBTAG00000014443", "url": "https://www.ensembl.org/id/ENSBTAG00000014443" } ] } } ], "crossref": [ { "id": "F1N363", "url": "https://alphafold.ebi.ac.uk/entry/F1N363", "database": "AlphaFoldDB", "categories": [] }, { "id": "ENSBTAG00000014443", "url": "https://bgee.org/?page=gene&gene_id=ENSBTAG00000014443", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "517977", "url": "https://www.ncbi.nlm.nih.gov/gene/517977", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "F1N363", "url": "https://www.orthodb.org/?gene=F1N363", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "NP_001421971", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001421971", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0AAA9S2M6", "url": "https://www.uniprot.org/uniprotkb/A0AAA9S2M6", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0AAA9S2M6-1", "url": "https://www.uniprot.org/uniprotkb/A0AAA9S2M6-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "F1N363", "url": "https://www.uniprot.org/uniprotkb/F1N363", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "F1N363-1", "url": "https://www.uniprot.org/uniprotkb/F1N363-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MNSLGQEEKGMNIRSLERAGRAGKQDGVVVSPGQEEEVQNCVSTRDSNWPVIKDHSVKLHRVSPLLLQCRITHSSRWIAQVLASELSLLAFILLVVMVFSKKWLCFERIRFYQHWPMNVTTKIYTSVHIMSLGLLHIYKSKSYSNSEWESFKLWTNHPAFGVAKITFCLALGLGIILTIWLHLPYIPGLQKLPFFGWIGTVMSFCEAFFVFFTLILFPVNIWLFELRKNLSIPLCWSYFIGWLVFILYVICAVLCYFNHGKFWCLILSHSTSSSSSSSSEHESVSELATSNTTVSQEEVLDPEKKKASLAPSPVYSSKSASSSFPSPNTEVGWPSSLQGIKEGGL", "length": 345, "header": "tr|F1N363-1|F1N363_BOVIN Isoform 1 of Outer dense fiber protein 4 OS=Bos taurus OX=9913 GN=ODF4 PE=4 SV=3 CANONICAL=F1N363-1" }, "isoforms": [ { "isoform_ac": "A0AAA9S2M6-1", "url": "https://www.uniprot.org/uniprotkb/A0AAA9S2M6/entry", "sequence": { "sequence": "MNSLGQEEKGMNIRSLERAGRAGKQDGVVVSPGQEEEVQNCVSTRDSNWPVIKDHSVKLHRVSPLLLQCRITHSSRWIAQVLASELSLLAFILLVVMVFSKKWLCFERIRFYQHWPMNVTTKIYTSVHIMSLGLLHIYKSKSYSNSEWESFKLWTNHPAFGVAKITFCLALGLGIILTIWLHLPYIPGLQKLPFFGWIGTVMSFCEAVLCYFNHGKFWCLILSHSTSSSSSSSSEHESVSELATSNTTVSQEEVLDPEKKKASLAPSPVYSSKSASSSFPSPNTEVGWPSSLQGIKEGGL", "length": 300, "header": "tr|A0AAA9S2M6-1|F1N363_BOVIN Computationally mapped isoform of Outer dense fiber protein 4 OS=Bos taurus OX=9913 GN=ODF4 PE=4 SV=1 CANONICAL=F1N363-1" }, "locus": { "chromosome": "19", "start_pos": 27954491, "end_pos": 27949700, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000105056.1", "url": "https://www.ensembl.org/id/ENSBTAT00000105056.1" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000076361.1", "url": "https://www.ensembl.org/id/ENSBTAP00000076361.1" } ] } }, { "isoform_ac": "F1N363-1", "url": "https://www.uniprot.org/uniprotkb/F1N363/entry", "sequence": { "sequence": "MNSLGQEEKGMNIRSLERAGRAGKQDGVVVSPGQEEEVQNCVSTRDSNWPVIKDHSVKLHRVSPLLLQCRITHSSRWIAQVLASELSLLAFILLVVMVFSKKWLCFERIRFYQHWPMNVTTKIYTSVHIMSLGLLHIYKSKSYSNSEWESFKLWTNHPAFGVAKITFCLALGLGIILTIWLHLPYIPGLQKLPFFGWIGTVMSFCEAFFVFFTLILFPVNIWLFELRKNLSIPLCWSYFIGWLVFILYVICAVLCYFNHGKFWCLILSHSTSSSSSSSSEHESVSELATSNTTVSQEEVLDPEKKKASLAPSPVYSSKSASSSFPSPNTEVGWPSSLQGIKEGGL", "length": 345, "header": "tr|F1N363-1|F1N363_BOVIN Isoform 1 of Outer dense fiber protein 4 OS=Bos taurus OX=9913 GN=ODF4 PE=4 SV=3 CANONICAL=F1N363-1" }, "locus": { "chromosome": "19", "start_pos": 27954491, "end_pos": 27949700, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000019205.6", "url": "https://www.ensembl.org/id/ENSBTAT00000019205.6" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000019205.6", "url": "https://www.ensembl.org/id/ENSBTAP00000019205.6" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [], "orthologs": [], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 1, "go_terms": [ { "name": "plasma membrane", "id": "GO:0005886", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005886", "evidence": [ { "database": "UniProtKB", "id": "F1N363", "url": "https://www.uniprot.org/uniprotkb/F1N363" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 2, "go_terms": [ { "name": "spermatogenesis", "id": "GO:0007283", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007283", "evidence": [ { "database": "UniProtKB", "id": "F1N363", "url": "https://www.uniprot.org/uniprotkb/F1N363" } ], "pmid": "" }, { "name": "cell differentiation", "id": "GO:0030154", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030154", "evidence": [ { "database": "UniProtKB", "id": "F1N363", "url": "https://www.uniprot.org/uniprotkb/F1N363" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 118, "end_pos": 120, "annotation": "n_glycosylation_sequon" }, { "start_pos": 229, "end_pos": 231, "annotation": "n_glycosylation_sequon" }, { "start_pos": 291, "end_pos": 293, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [ { "pdb_id": "AF-F1N363-F1", "pdb_chain": "global", "start_pos": 1, "end_pos": 345, "overlap": "1.0", "method": "AlphaFold", "type": "alphafold", "resolution": -1.0, "url": "https://data.glygen.org/ln2downloads/pdb/current/AF-F1N363-F1.pdb", "url_external": "https://alphafold.ebi.ac.uk/entry/F1N363" } ], "lectin_list": [], "domain_list": [], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 118, "end_pos": 120 }, { "start_pos": 229, "end_pos": 231 }, { "start_pos": 291, "end_pos": 293 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ], "tool_support": { "graph_view": "yes" } }, { "uniprot_canonical_ac": "F6QDA3-1", "uniprot_ac": "F6QDA3", "uniprot_id": "F6QDA3_BOVIN", "mass": { "chemical_mass": 42505.0, "monoisotopic_mass": 42505.0 }, "refseq": {}, "gene_names": [ { "name": "KHDRBS3", "type": "recommended", "evidence": [ { "id": "F6QDA3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F6QDA3" } ] } ], "protein_names": [ { "name": "KH RNA binding domain containing, signal transduction associated 3", "type": "synonym", "evidence": [ { "id": "F6QDA3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F6QDA3/entry#names_and_taxonomy" } ] } ], "function": [], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Bos taurus", "taxid": 9913, "evidence": [ { "database": "UniProtKB", "id": "F6QDA3", "url": "https://www.uniprot.org/uniprotkb/F6QDA3" } ], "common_name": "Bovine", "glygen_name": "Bovine", "reference_species": "Bos taurus [9913]" } ], "gene": [ { "name": "KHDRBS3", "url": "https://www.uniprot.org/uniprotkb/F6QDA3", "locus": { "chromosome": "14", "start_pos": 6392366, "end_pos": 6544685, "strand": "+", "evidence": [ { "database": "Ensembl Gene", "id": "ENSBTAG00000002181", "url": "https://www.ensembl.org/id/ENSBTAG00000002181" } ] } } ], "crossref": [ { "id": "F6QDA3", "url": "https://alphafold.ebi.ac.uk/entry/F6QDA3", "database": "AlphaFoldDB", "categories": [] }, { "id": "ENSBTAG00000002181", "url": "https://bgee.org/?page=gene&gene_id=ENSBTAG00000002181", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "cd22470", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd22470", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "615095", "url": "https://www.ncbi.nlm.nih.gov/gene/615095", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR004087", "url": "https://www.ebi.ac.uk/interpro/entry/IPR004087", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR032335", "url": "https://www.ebi.ac.uk/interpro/entry/IPR032335", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR032571", "url": "https://www.ebi.ac.uk/interpro/entry/IPR032571", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR036612", "url": "https://www.ebi.ac.uk/interpro/entry/IPR036612", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR045071", "url": "https://www.ebi.ac.uk/interpro/entry/IPR045071", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR055256", "url": "https://www.ebi.ac.uk/interpro/entry/IPR055256", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "A0A3Q1LQR7", "url": "https://www.orthodb.org/?gene=A0A3Q1LQR7", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR11208", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR11208", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR11208:SF29", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR11208:SF29", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF16274", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF16274", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF16568", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF16568", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF22675", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF22675", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "A0A3Q1LQR7", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1LQR7", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A3Q1LQR7-1", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1LQR7-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0AAA9S3T9", "url": "https://www.uniprot.org/uniprotkb/A0AAA9S3T9", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0AAA9S3T9-1", "url": "https://www.uniprot.org/uniprotkb/A0AAA9S3T9-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0AAA9SVL1", "url": "https://www.uniprot.org/uniprotkb/A0AAA9SVL1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0AAA9SVL1-1", "url": "https://www.uniprot.org/uniprotkb/A0AAA9SVL1-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "F6QDA3", "url": "https://www.uniprot.org/uniprotkb/F6QDA3", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "F6QDA3-1", "url": "https://www.uniprot.org/uniprotkb/F6QDA3-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MEEKYLPELMAEKDSLDPSFTHALRLVNQEIEKFQKGEGKDEEKYIDVVINKNMKLGQKVLIPVKQFPKFNFVGKLLGPRGNSLKRLQEETLTKMSILGKGSMRDKAKEEELRKSGEAKYFHLNDDLHVLIEVFAPPAEAYARMGHALEEIKKFLIPDYNDEIRQAQLQELTYLNGGSENADVPVVRGKPTLRTRGVPTPAITRGRGGVSARPVGVGVPRGTPASRGVLSTRGPVSRGRGLLTPRARGVPPTGYRPPPPPPTQETYGDYDYDDGYGTAYDEQSYDSYDNSYSAPTQSCSGRSERPMQPSLSQAKLLTAPCPELLLLPLPRLSGADYYDYGHGLSEETYDSYGQEEWTNSRHKAPSARTAKGVYRDQPYGRY", "length": 381, "header": "tr|F6QDA3-1|F6QDA3_BOVIN Isoform 1 of KH RNA binding domain containing, signal transduction associated 3 OS=Bos taurus OX=9913 GN=KHDRBS3 PE=3 SV=1 CANONICAL=F6QDA3-1" }, "isoforms": [ { "isoform_ac": "A0A3Q1LQR7-1", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1LQR7/entry", "sequence": { "sequence": "MEEKYLPELMAEKDSLDPSFTHALRLVNQEIEKFQKGEGKDEEKYIDVVINKNMKLGQKVLIPVKQFPKFNFVGKLLGPRGNSLKRLQEETLTKMSILGKGSMRDKAKEEELRKSGEAKYFHLNDDLHVLIEVFAPPAEAYARMGHALEEIKKFLIPDYNDEIRQAQLQELTYLNGGSENADVPVVRGKPTLRTRGVPTPAITRGRGGVSARPVGVGVPRGTPASRGVLSTRGPVSRGRGLLTPRARGVPPTGYRPPPPPPTQETYGDYDYDDGYGTAYDEQSYDSYDNSYSAPTQSGADYYDYGHGLSEETYDSYGMSATLESERKAAVSPADTGTFLPITDCLRIVNSPTCLVSK", "length": 357, "header": "tr|A0A3Q1LQR7-1|A0A3Q1LQR7_BOVIN Computationally mapped isoform of KH RNA binding domain containing, signal transduction associated 3 OS=Bos taurus OX=9913 GN=KHDRBS3 PE=3 SV=2 CANONICAL=F6QDA3-1" }, "locus": { "chromosome": "14", "start_pos": 6544677, "end_pos": 6392497, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000070325.2", "url": "https://www.ensembl.org/id/ENSBTAT00000070325.2" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000059447.2", "url": "https://www.ensembl.org/id/ENSBTAP00000059447.2" } ] } }, { "isoform_ac": "A0AAA9S3T9-1", "url": "https://www.uniprot.org/uniprotkb/A0AAA9S3T9/entry", "sequence": { "sequence": "MDEIEKFQKGEGKDEEKYIDVVINKNMKLGQKVLIPVKQFPKFNFVGKLLGPRGNSLKRLQEETLTKMSILGKGSMRDKAKEEELRKSGEAKYFHLNDDLHVLIEVFAPPAEAYARMGHALEEIKKFLIPDYNDEIRQAQLQELTYLNGGSENADVPVVRGKPTLRTRGVPTPAITRGRGGVSARPVGVGVPRGTPASRGVLSTRGPVSRGRGLLTPRARGVPPTGYRPPPPPPTQETYGDYDYDDGYGTAYDEQSYDSYDNSYSAPTQSGADYYDYGHGLSEETYDSYGQEEWTNSRHKAPSARTAKGVYRDQPYGRY", "length": 319, "header": "tr|A0AAA9S3T9-1|F6QDA3_BOVIN Computationally mapped isoform of KH RNA binding domain containing, signal transduction associated 3 OS=Bos taurus OX=9913 GN=KHDRBS3 PE=3 SV=1 CANONICAL=F6QDA3-1" }, "locus": { "chromosome": "14", "start_pos": 6543515, "end_pos": 6401249, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000135661.1", "url": "https://www.ensembl.org/id/ENSBTAT00000135661.1" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000078456.1", "url": "https://www.ensembl.org/id/ENSBTAP00000078456.1" } ] } }, { "isoform_ac": "A0AAA9SVL1-1", "url": "https://www.uniprot.org/uniprotkb/A0AAA9SVL1/entry", "sequence": { "sequence": "MDEIEKFQKGEGKDEEKYIDVVINKNMKLGQKVLIPVKQFPKDYDDGYGTAYDEQSYDSYDNSYSAPTQSGADYYDYGHGLSEETYDSYGQEEWTNSRHKAPSARTAKGVYRDQPYGRY", "length": 119, "header": "tr|A0AAA9SVL1-1|F6QDA3_BOVIN Computationally mapped isoform of KH RNA binding domain containing, signal transduction associated 3 OS=Bos taurus OX=9913 GN=KHDRBS3 PE=3 SV=2 CANONICAL=F6QDA3-1" }, "locus": { "chromosome": "14", "start_pos": 6543515, "end_pos": 6401249, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000090253.2", "url": "https://www.ensembl.org/id/ENSBTAT00000090253.2" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000088230.2", "url": "https://www.ensembl.org/id/ENSBTAP00000088230.2" } ] } }, { "isoform_ac": "F6QDA3-1", "url": "https://www.uniprot.org/uniprotkb/F6QDA3/entry", "sequence": { "sequence": "MEEKYLPELMAEKDSLDPSFTHALRLVNQEIEKFQKGEGKDEEKYIDVVINKNMKLGQKVLIPVKQFPKFNFVGKLLGPRGNSLKRLQEETLTKMSILGKGSMRDKAKEEELRKSGEAKYFHLNDDLHVLIEVFAPPAEAYARMGHALEEIKKFLIPDYNDEIRQAQLQELTYLNGGSENADVPVVRGKPTLRTRGVPTPAITRGRGGVSARPVGVGVPRGTPASRGVLSTRGPVSRGRGLLTPRARGVPPTGYRPPPPPPTQETYGDYDYDDGYGTAYDEQSYDSYDNSYSAPTQSCSGRSERPMQPSLSQAKLLTAPCPELLLLPLPRLSGADYYDYGHGLSEETYDSYGQEEWTNSRHKAPSARTAKGVYRDQPYGRY", "length": 381, "header": "tr|F6QDA3-1|F6QDA3_BOVIN Isoform 1 of KH RNA binding domain containing, signal transduction associated 3 OS=Bos taurus OX=9913 GN=KHDRBS3 PE=3 SV=1 CANONICAL=F6QDA3-1" }, "locus": { "chromosome": "14", "start_pos": 6544677, "end_pos": 6401249, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000002827.7", "url": "https://www.ensembl.org/id/ENSBTAT00000002827.7" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000002827.6", "url": "https://www.ensembl.org/id/ENSBTAP00000002827.6" } ] } } ], "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "other", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 199, "start_aa": "Thr", "end_pos": 199, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr199", "evidence": [ { "id": "", "database": "GlyGen", "url": "https://data.glygen.org/" } ], "filter_code": "000000000000000010000.00000000001000.0.01000" }, { "glytoucan_ac": "", "type": "O-linked", "subtype": "other", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 262, "start_aa": "Thr", "end_pos": 262, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr262", "evidence": [ { "id": "", "database": "GlyGen", "url": "https://data.glygen.org/" } ], "filter_code": "000000000000000010000.00000000001000.0.01000" } ], "phosphorylation": [], "glycation": [], "keywords": [ "glycoprotein", "glycoprotein_predicted" ], "publication": [], "pathway": [], "orthologs": [], "go_annotation": { "categories": [ { "name": "Molecular Function", "total": 3, "go_terms": [ { "name": "RNA binding", "id": "GO:0003723", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003723", "evidence": [ { "database": "UniProtKB", "id": "F6QDA3", "url": "https://www.uniprot.org/uniprotkb/F6QDA3" } ], "pmid": "" }, { "name": "SH3 domain binding", "id": "GO:0017124", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0017124", "evidence": [ { "database": "UniProtKB", "id": "F6QDA3", "url": "https://www.uniprot.org/uniprotkb/F6QDA3" } ], "pmid": "" }, { "name": "identical protein binding", "id": "GO:0042802", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0042802", "evidence": [ { "database": "UniProtKB", "id": "F6QDA3", "url": "https://www.uniprot.org/uniprotkb/F6QDA3" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 3, "go_terms": [ { "name": "nucleus", "id": "GO:0005634", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005634", "evidence": [ { "database": "UniProtKB", "id": "F6QDA3", "url": "https://www.uniprot.org/uniprotkb/F6QDA3" } ], "pmid": "" }, { "name": "nucleoplasm", "id": "GO:0005654", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005654", "evidence": [ { "database": "UniProtKB", "id": "F6QDA3", "url": "https://www.uniprot.org/uniprotkb/F6QDA3" } ], "pmid": "" }, { "name": "protein-containing complex", "id": "GO:0032991", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0032991", "evidence": [ { "database": "UniProtKB", "id": "F6QDA3", "url": "https://www.uniprot.org/uniprotkb/F6QDA3" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 2, "go_terms": [ { "name": "DNA-templated transcription", "id": "GO:0006351", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006351", "evidence": [ { "database": "UniProtKB", "id": "F6QDA3", "url": "https://www.uniprot.org/uniprotkb/F6QDA3" } ], "pmid": "" }, { "name": "regulation of mRNA splicing, via spliceosome", "id": "GO:0048024", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0048024", "evidence": [ { "database": "UniProtKB", "id": "F6QDA3", "url": "https://www.uniprot.org/uniprotkb/F6QDA3" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "F6QDA3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F6QDA3" }, { "id": "SM00322", "database": "SMART", "url": "http://smart.embl.de/smart/do_annotation.pl?DOMAIN=SM00322" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "K Homology", "eco_id": "ECO_0000259", "start_pos": 54, "end_pos": 152, "start_aa": "Met", "end_aa": "Lys", "glycosite_overlap": [] } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [ 199, 262 ], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 2 }, { "field": "total_sites", "count": 2 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 2 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "exact_sites", "count": 2 }, { "field": "exact_o_linked_sites", "count": 2 }, { "field": "fuzzy_sites", "count": 0 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_pos", "start_aa", "end_pos", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 2 }, { "field": "total_sites", "count": 2 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 2 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "exact_sites", "count": 2 }, { "field": "exact_o_linked_sites", "count": 2 }, { "field": "fuzzy_sites", "count": 0 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_pos", "start_aa", "end_pos", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ], "tool_support": { "graph_view": "yes" } }, { "uniprot_canonical_ac": "F6PXF3-1", "uniprot_ac": "F6PXF3", "uniprot_id": "F6PXF3_BOVIN", "mass": { "chemical_mass": 50484.0, "monoisotopic_mass": 50484.0 }, "refseq": {}, "gene_names": [ { "name": "STAMBP", "type": "recommended", "evidence": [ { "id": "F6PXF3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F6PXF3" } ] } ], "protein_names": [ { "name": "STAM-binding protein", "type": "recommended", "evidence": [ { "id": "F6PXF3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F6PXF3/entry#names_and_taxonomy" } ] }, { "name": "Associated molecule with the SH3 domain of STAM", "type": "synonym", "evidence": [ { "id": "F6PXF3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F6PXF3/entry#names_and_taxonomy" } ] } ], "function": [ { "annotation": "Zinc metalloprotease that specifically cleaves 'Lys-63'-linked polyubiquitin chains. Does not cleave 'Lys-48'-linked polyubiquitin chains. Plays a role in signal transduction for cell growth and MYC induction mediated by IL-2 and GM-CSF. Potentiates BMP (bone morphogenetic protein) signaling by antagonizing the inhibitory action of SMAD6 and SMAD7. Has a key role in regulation of cell surface receptor-mediated endocytosis and ubiquitin-dependent sorting of receptors to lysosomes. Endosomal localization of STAMBP is required for efficient EGFR degradation but not for its internalization. Involved in the negative regulation of PI3K-AKT-mTOR and RAS-MAP signaling pathways.", "evidence": [ { "database": "UniProtKB", "id": "A0AAA9S523", "url": "https://www.uniprot.org/uniprotkb/A0AAA9S523#function" }, { "database": "UniProtKB", "id": "ARBA00058580", "url": "https://www.uniprot.org/uniprotkb/ARBA00058580#function" }, { "database": "UniProtKB", "id": "F6PXF3", "url": "https://www.uniprot.org/uniprotkb/F6PXF3#function" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Bos taurus", "taxid": 9913, "evidence": [ { "database": "UniProtKB", "id": "F6PXF3", "url": "https://www.uniprot.org/uniprotkb/F6PXF3" } ], "common_name": "Bovine", "glygen_name": "Bovine", "reference_species": "Bos taurus [9913]" } ], "gene": [ { "name": "STAMBP", "url": "https://www.uniprot.org/uniprotkb/F6PXF3", "locus": { "chromosome": "11", "start_pos": 10793276, "end_pos": 10817521, "strand": "+", "evidence": [ { "database": "Ensembl Gene", "id": "ENSBTAG00000009600", "url": "https://www.ensembl.org/id/ENSBTAG00000009600" } ] } } ], "crossref": [ { "id": "F6PXF3", "url": "https://alphafold.ebi.ac.uk/entry/F6PXF3", "database": "AlphaFoldDB", "categories": [] }, { "id": "cd08066", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd08066", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "IPR000555", "url": "https://www.ebi.ac.uk/interpro/entry/IPR000555", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR015063", "url": "https://www.ebi.ac.uk/interpro/entry/IPR015063", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR037518", "url": "https://www.ebi.ac.uk/interpro/entry/IPR037518", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR044098", "url": "https://www.ebi.ac.uk/interpro/entry/IPR044098", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "PTHR12947", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR12947", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR12947:SF8", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR12947:SF8", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF01398", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF01398", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF08969", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF08969", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "A0AAA9S523", "url": "https://www.uniprot.org/uniprotkb/A0AAA9S523", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0AAA9S523-1", "url": "https://www.uniprot.org/uniprotkb/A0AAA9S523-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0AAA9TRE0", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TRE0", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0AAA9TRE0-1", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TRE0-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "F6PXF3", "url": "https://www.uniprot.org/uniprotkb/F6PXF3", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "F6PXF3-1", "url": "https://www.uniprot.org/uniprotkb/F6PXF3-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MPDVTFSEAPRVVRGGQDFLVLMSDHGDVSLPPEDRVRALSHRGSAVEINEDIPPRRYFRSGVEIIRMASVYCEEGNIEYAFILYNKYITLFIEKLPKHRDYKSAVIPEKKDTVKKLKEIAFPKAEELKAELLKRYTKEYLEYNEEKKKEAEEFARNVAMQEELEKERRRVAQQKQQQLEQEQFHAFEEMIRNQELEKERLKIVQEFGKVDPGLGGPLVPDLETPSLDVFPTVPAIPTQPSDCNAAVRLAKPPVVDRSLKPGALNNLEAPTIDGLRHVVVPGKLCPQFLQLAGANTTRGVETCGILCGKLMRNEFTITHVLIPKQSAGSDYCNTENEEELFLIQDQQGLITLGWIHTHPTQTAFLSSVDLHTHCSYQMMLPESIAIVCSPKFQETGFFRLTDHGLEEISSCRQKGFHPHSKDPPLFCSCSHVTVVDRAVTVTDLR", "length": 445, "header": "tr|F6PXF3-1|F6PXF3_BOVIN Isoform 1 of STAM-binding protein OS=Bos taurus OX=9913 GN=STAMBP PE=3 SV=1 CANONICAL=F6PXF3-1" }, "isoforms": [ { "isoform_ac": "A0AAA9S523-1", "url": "https://www.uniprot.org/uniprotkb/A0AAA9S523/entry", "sequence": { "sequence": "MSDHGDVSLPPEDRVRALSHRGSAVEINEDIPPRRYFRSGVEIIRMASVYCEEGNIEYAFILYNKYITLFIEKLPKHRDYKSAVIPEKKDTVKKLKEIAFPKAEELKAELLKRYTKEYLEYNEEKKKEAEEFARNVAMQEELEKERRRVAQQKQQQLEQEQFHAFEEMIRNQELEKERLKIVQEFGKPSDCNAAVRLAKPPVVDRSLKPGALNNLEGTPTIDGLRHVVVPGKLCPQFLQLAGANTTRGVETCGILCGKLMRNEFTITHVLIPKQSAGSDYCNTENEEELFLIQDQQGLITLGWIHTHPTQTAFLSSVDLHTHCSYQMMLPESIAIVCSPKFQETGFFRLTDHGLEEISSCRQKGFHPHSKDPPLFCSCSHVTVVDRAVTVTDLR", "length": 394, "header": "tr|A0AAA9S523-1|F6PXF3_BOVIN Computationally mapped isoform of STAM-binding protein OS=Bos taurus OX=9913 GN=STAMBP PE=3 SV=1 CANONICAL=F6PXF3-1" }, "locus": { "chromosome": "11", "start_pos": 10815097, "end_pos": 10793881, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000120219.1", "url": "https://www.ensembl.org/id/ENSBTAT00000120219.1" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000078331.1", "url": "https://www.ensembl.org/id/ENSBTAP00000078331.1" } ] } }, { "isoform_ac": "A0AAA9TRE0-1", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TRE0/entry", "sequence": { "sequence": "MSDHGDVSLPPEDRVRALSHRGSAVEINEDIPPRRYFRSGVEIIRMASVYCEEGNIEYAFILYNKYITLFIEKLPKHRDYKSAVIPEKKDTVKKLKEIAFPKAEELKAELLKRYTKEYLEYNEEKTHPTQTAFLSSVDLHTHCSYQMMLPESIAIVCSPKFQETGFFRLTDHGLEEISSCRQKGFHPHSKDPPLFCSCSHVTVVDRAVTVTDLR", "length": 214, "header": "tr|A0AAA9TRE0-1|F6PXF3_BOVIN Computationally mapped isoform of STAM-binding protein OS=Bos taurus OX=9913 GN=STAMBP PE=3 SV=1 CANONICAL=F6PXF3-1" }, "locus": { "chromosome": "11", "start_pos": 10815097, "end_pos": 10793881, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000110980.1", "url": "https://www.ensembl.org/id/ENSBTAT00000110980.1" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000099026.1", "url": "https://www.ensembl.org/id/ENSBTAP00000099026.1" } ] } }, { "isoform_ac": "F6PXF3-1", "url": "https://www.uniprot.org/uniprotkb/F6PXF3/entry", "sequence": { "sequence": "MPDVTFSEAPRVVRGGQDFLVLMSDHGDVSLPPEDRVRALSHRGSAVEINEDIPPRRYFRSGVEIIRMASVYCEEGNIEYAFILYNKYITLFIEKLPKHRDYKSAVIPEKKDTVKKLKEIAFPKAEELKAELLKRYTKEYLEYNEEKKKEAEEFARNVAMQEELEKERRRVAQQKQQQLEQEQFHAFEEMIRNQELEKERLKIVQEFGKVDPGLGGPLVPDLETPSLDVFPTVPAIPTQPSDCNAAVRLAKPPVVDRSLKPGALNNLEAPTIDGLRHVVVPGKLCPQFLQLAGANTTRGVETCGILCGKLMRNEFTITHVLIPKQSAGSDYCNTENEEELFLIQDQQGLITLGWIHTHPTQTAFLSSVDLHTHCSYQMMLPESIAIVCSPKFQETGFFRLTDHGLEEISSCRQKGFHPHSKDPPLFCSCSHVTVVDRAVTVTDLR", "length": 445, "header": "tr|F6PXF3-1|F6PXF3_BOVIN Isoform 1 of STAM-binding protein OS=Bos taurus OX=9913 GN=STAMBP PE=3 SV=1 CANONICAL=F6PXF3-1" }, "locus": { "chromosome": "11", "start_pos": 10817446, "end_pos": 10793881, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000012633.7", "url": "https://www.ensembl.org/id/ENSBTAT00000012633.7" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000012633.6", "url": "https://www.ensembl.org/id/ENSBTAP00000012633.6" } ] } } ], "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "other", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 232, "start_aa": "Thr", "end_pos": 232, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr232", "evidence": [ { "id": "", "database": "GlyGen", "url": "https://data.glygen.org/" } ], "filter_code": "000000000000000010000.00000000001000.0.01000" } ], "phosphorylation": [], "glycation": [], "keywords": [ "glycoprotein", "glycoprotein_predicted" ], "publication": [], "pathway": [], "orthologs": [], "go_annotation": { "categories": [ { "name": "Biological Process", "total": 5, "go_terms": [ { "name": "proteolysis", "id": "GO:0006508", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006508", "evidence": [ { "database": "UniProtKB", "id": "F6PXF3", "url": "https://www.uniprot.org/uniprotkb/F6PXF3" } ], "pmid": "" }, { "name": "protein K63-linked deubiquitination", "id": "GO:0070536", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0070536", "evidence": [ { "database": "UniProtKB", "id": "F6PXF3", "url": "https://www.uniprot.org/uniprotkb/F6PXF3" } ], "pmid": "" }, { "name": "protein deubiquitination", "id": "GO:0016579", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016579", "evidence": [ { "database": "UniProtKB", "id": "F6PXF3", "url": "https://www.uniprot.org/uniprotkb/F6PXF3" } ], "pmid": "" }, { "name": "negative regulation of Ras protein signal transduction", "id": "GO:0046580", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0046580", "evidence": [ { "database": "UniProtKB", "id": "F6PXF3", "url": "https://www.uniprot.org/uniprotkb/F6PXF3" } ], "pmid": "" }, { "name": "negative regulation of phosphatidylinositol 3-kinase/protein kinase B signal transduction", "id": "GO:0051898", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0051898", "evidence": [ { "database": "UniProtKB", "id": "F6PXF3", "url": "https://www.uniprot.org/uniprotkb/F6PXF3" } ], "pmid": "" } ] }, { "name": "Molecular Function", "total": 4, "go_terms": [ { "name": "metal ion binding", "id": "GO:0046872", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0046872", "evidence": [ { "database": "UniProtKB", "id": "F6PXF3", "url": "https://www.uniprot.org/uniprotkb/F6PXF3" } ], "pmid": "" }, { "name": "K63-linked deubiquitinase activity", "id": "GO:0061578", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0061578", "evidence": [ { "database": "UniProtKB", "id": "F6PXF3", "url": "https://www.uniprot.org/uniprotkb/F6PXF3" } ], "pmid": "" }, { "name": "metal-dependent deubiquitinase activity", "id": "GO:0140492", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0140492", "evidence": [ { "database": "UniProtKB", "id": "F6PXF3", "url": "https://www.uniprot.org/uniprotkb/F6PXF3" } ], "pmid": "" }, { "name": "protein domain specific binding", "id": "GO:0019904", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0019904", "evidence": [ { "database": "UniProtKB", "id": "F6PXF3", "url": "https://www.uniprot.org/uniprotkb/F6PXF3" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 3, "go_terms": [ { "name": "cleavage furrow", "id": "GO:0032154", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0032154", "evidence": [ { "database": "UniProtKB", "id": "F6PXF3", "url": "https://www.uniprot.org/uniprotkb/F6PXF3" } ], "pmid": "" }, { "name": "nucleoplasm", "id": "GO:0005654", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005654", "evidence": [ { "database": "UniProtKB", "id": "F6PXF3", "url": "https://www.uniprot.org/uniprotkb/F6PXF3" } ], "pmid": "" }, { "name": "cytosol", "id": "GO:0005829", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005829", "evidence": [ { "database": "UniProtKB", "id": "F6PXF3", "url": "https://www.uniprot.org/uniprotkb/F6PXF3" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 295, "end_pos": 297, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "F6PXF3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F6PXF3" }, { "id": "PS50249", "database": "PROSITE", "url": "https://prosite.expasy.org/PS50249" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "MPN", "eco_id": "ECO_0000259", "start_pos": 278, "end_pos": 409, "start_aa": "Val", "end_aa": "Ser", "glycosite_overlap": [] } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [ 232 ], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 295, "end_pos": 297 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 1 }, { "field": "total_sites", "count": 1 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 1 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "exact_sites", "count": 1 }, { "field": "exact_o_linked_sites", "count": 1 }, { "field": "fuzzy_sites", "count": 0 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_pos", "start_aa", "end_pos", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 1 }, { "field": "total_sites", "count": 1 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 1 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "exact_sites", "count": 1 }, { "field": "exact_o_linked_sites", "count": 1 }, { "field": "fuzzy_sites", "count": 0 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_pos", "start_aa", "end_pos", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ], "tool_support": { "graph_view": "yes" } }, { "uniprot_canonical_ac": "F6RGB4-1", "uniprot_ac": "F6RGB4", "uniprot_id": "F6RGB4_BOVIN", "mass": { "chemical_mass": 25078.0, "monoisotopic_mass": 25078.0 }, "refseq": {}, "gene_names": [ { "name": "GRB2", "type": "recommended", "evidence": [ { "id": "F6RGB4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F6RGB4" } ] } ], "protein_names": [ { "name": "Growth factor receptor-bound protein 2", "type": "recommended", "evidence": [ { "id": "F6RGB4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F6RGB4/entry#names_and_taxonomy" } ] }, { "name": "Adapter protein GRB2", "type": "synonym", "evidence": [ { "id": "F6RGB4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F6RGB4/entry#names_and_taxonomy" } ] }, { "name": "SH2/SH3 adapter GRB2", "type": "synonym", "evidence": [ { "id": "F6RGB4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F6RGB4/entry#names_and_taxonomy" } ] } ], "function": [], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Bos taurus", "taxid": 9913, "evidence": [ { "database": "UniProtKB", "id": "F6RGB4", "url": "https://www.uniprot.org/uniprotkb/F6RGB4" } ], "common_name": "Bovine", "glygen_name": "Bovine", "reference_species": "Bos taurus [9913]" } ], "gene": [ { "name": "GRB2", "url": "https://www.uniprot.org/uniprotkb/F6RGB4", "locus": { "chromosome": "19", "start_pos": 56182489, "end_pos": 56117209, "strand": "-", "evidence": [ { "database": "Ensembl Gene", "id": "ENSBTAG00000004736", "url": "https://www.ensembl.org/id/ENSBTAG00000004736" } ] } } ], "crossref": [ { "id": "F6RGB4", "url": "https://alphafold.ebi.ac.uk/entry/F6RGB4", "database": "AlphaFoldDB", "categories": [] }, { "id": "cd09941", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd09941", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "cd11946", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd11946", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "cd11949", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd11949", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "IPR000980", "url": "https://www.ebi.ac.uk/interpro/entry/IPR000980", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR001452", "url": "https://www.ebi.ac.uk/interpro/entry/IPR001452", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR035641", "url": "https://www.ebi.ac.uk/interpro/entry/IPR035641", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR035643", "url": "https://www.ebi.ac.uk/interpro/entry/IPR035643", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR036028", "url": "https://www.ebi.ac.uk/interpro/entry/IPR036028", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR036860", "url": "https://www.ebi.ac.uk/interpro/entry/IPR036860", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR043539", "url": "https://www.ebi.ac.uk/interpro/entry/IPR043539", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "PTHR46037", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR46037", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00017", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00017", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF00018", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00018", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "A0AAA9S615", "url": "https://www.uniprot.org/uniprotkb/A0AAA9S615", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0AAA9S615-1", "url": "https://www.uniprot.org/uniprotkb/A0AAA9S615-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0AAA9S861", "url": "https://www.uniprot.org/uniprotkb/A0AAA9S861", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0AAA9S861-1", "url": "https://www.uniprot.org/uniprotkb/A0AAA9S861-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0AAA9SNB1", "url": "https://www.uniprot.org/uniprotkb/A0AAA9SNB1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0AAA9SNB1-1", "url": "https://www.uniprot.org/uniprotkb/A0AAA9SNB1-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0AAA9T136", "url": "https://www.uniprot.org/uniprotkb/A0AAA9T136", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0AAA9T136-1", "url": "https://www.uniprot.org/uniprotkb/A0AAA9T136-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0AAA9T8F5", "url": "https://www.uniprot.org/uniprotkb/A0AAA9T8F5", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0AAA9T8F5-1", "url": "https://www.uniprot.org/uniprotkb/A0AAA9T8F5-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0AAA9TWK5", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TWK5", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0AAA9TWK5-1", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TWK5-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "F6RGB4", "url": "https://www.uniprot.org/uniprotkb/F6RGB4", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "F6RGB4-1", "url": "https://www.uniprot.org/uniprotkb/F6RGB4-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MEAIAKYDFKATADDELSFKRGDILKVLNEECDQNWYKAELNGKDGFIPKNYIEMKPHPWFFGKIPRAKAEEMLSKQRHDGAFLIRESESAPGDFSLSVKFGNDVQHFKVLRDGAGKYFLWVVKFNSLNELVDYHRSTSVSRNQQIFLRDIEQVPQPTYVQALFDFDPQEDGELGFRRGDFIHVMDNSDPNWWKGACHGQTGMFPRNYVTPVNRNV", "length": 216, "header": "tr|F6RGB4-1|F6RGB4_BOVIN Isoform 1 of Growth factor receptor-bound protein 2 OS=Bos taurus OX=9913 GN=GRB2 PE=3 SV=1 CANONICAL=F6RGB4-1" }, "isoforms": [ { "isoform_ac": "A0AAA9S615-1", "url": "https://www.uniprot.org/uniprotkb/A0AAA9S615/entry", "sequence": { "sequence": "MFLRHTRGKRVSVQPLSQVLNEECDQNWYKAELNGKDGFIPKNYIEMKPHPWFFGKIPRAKAEEMLSKQRHDGAFLIRESESAPGDFSLSVKFGNDVQHFKVLRDGAGKYFLWVVKFNSLNELVDYHRSTSVSRNQQIFLRDIEQVPQQPTYVQALFDFDPQEDGELGFRRGDFIHVMDNSDPNWWKGACHGQTGMFPRNYVTPVNRNV", "length": 209, "header": "tr|A0AAA9S615-1|F6RGB4_BOVIN Computationally mapped isoform of Growth factor receptor-bound protein 2 OS=Bos taurus OX=9913 GN=GRB2 PE=3 SV=1 CANONICAL=F6RGB4-1" }, "locus": { "chromosome": "19", "start_pos": 56181485, "end_pos": 56132356, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000100980.2", "url": "https://www.ensembl.org/id/ENSBTAT00000100980.2" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000077608.1", "url": "https://www.ensembl.org/id/ENSBTAP00000077608.1" } ] } }, { "isoform_ac": "A0AAA9S861-1", "url": "https://www.uniprot.org/uniprotkb/A0AAA9S861/entry", "sequence": { "sequence": 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"categories": [ "Protein Classification" ] }, { "id": "PTHR31158:SF3", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR31158:SF3", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF10204", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF10204", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "A0AAA9S6S0", "url": "https://www.uniprot.org/uniprotkb/A0AAA9S6S0", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0AAA9S6S0-1", "url": "https://www.uniprot.org/uniprotkb/A0AAA9S6S0-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "F6PV20", "url": "https://www.uniprot.org/uniprotkb/F6PV20", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "F6PV20-1", "url": "https://www.uniprot.org/uniprotkb/F6PV20-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MAAFGHTFPFYAGPKPTFPTDTTLAVIVAIFLTSLVTFIIILPGIRGKMRLFWMLRVVTSLFIGAVILAVNFSSEWSVGQVSTNTSYKAFSSQWISANVGLQIGLGGVNITLTGTPVQQLNETIDYNEEFTWRLGENYAEEYANALEKGLPDPVLYLAEKFTPHSPCGLHGQYRLAGHYTSAMLWSWLSRVAFLCWLLANVMLSMPVLVYGGHMLLATGLFQLLGLLFFSTATSLTPPCPLRLGAATLHTHRGPAYWITLTTGLLCVLLGLAMVVAHRMQPHRLKAFFSQSVGEDPVLELNPEEGGLLSPRYRSITESPEPQDIPLSEASSEAPCEEPDCAL", "length": 342, "header": "tr|F6PV20-1|F6PV20_BOVIN Isoform 1 of Dual oxidase maturation factor 1 OS=Bos taurus OX=9913 GN=DUOXA1 PE=3 SV=1 CANONICAL=F6PV20-1" }, "isoforms": [ { "isoform_ac": "A0AAA9S6S0-1", "url": "https://www.uniprot.org/uniprotkb/A0AAA9S6S0/entry", "sequence": { "sequence": "MAAFGHTFPFYAGPKPTFPTDTTLAVIVAIFLTSLVTFIIILPGIRGKMRLFWMLRVVTSLFIGAVILGTPVQQLNETIDYNEEFTWRLGENYAEEYANALEKGLPDPVLYLAEKFTPHSPCGLHGQYRLAGHYTSAMLWVAFLCWLLANVMLSMPVLVYGGHMLLATGLFQLLGLLFFSTATSLTPPCPLRLGAATLHTHRGPAYWITLTTGLLCVLLGLAMVVAHRMQPHRLKAFFSQSVGEDPVLELNPEEGGLLSPRYRSITESPEPQDIPLSEASSEAPCEEPDCAL", "length": 292, "header": "tr|A0AAA9S6S0-1|F6PV20_BOVIN 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"length": 1289, "header": "tr|A0AAA9S9N3-1|F1N7C3_BOVIN Computationally mapped isoform of SOS Ras/Rac guanine nucleotide exchange factor 1 OS=Bos taurus OX=9913 GN=SOS1 PE=4 SV=1 CANONICAL=F1N7C3-1" }, "locus": { "chromosome": "11", "start_pos": 21434854, "end_pos": 21308262, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000132612.1", "url": "https://www.ensembl.org/id/ENSBTAT00000132612.1" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000082001.1", "url": "https://www.ensembl.org/id/ENSBTAP00000082001.1" } ] } }, { "isoform_ac": "A0AAA9TIR9-1", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TIR9/entry", "sequence": { "sequence": "MQAQQLPYEFFSEENAPKWRGLLVPALKKVQGQVHPTLESSDDALQYVEELILQLLNMLCQAQPRSASDVEERVQKSFPHPIDKWAIADAQSAIEKRKRRNPLSLPVEKIHPLLKEVLGYKIDHQVSVYIVAVLEYISADILKLVGNYVRNIRHYEITKQDIKVAMCADKVLMDMFHQDVEDINILSLTDEEPSTSGEQTYYDLVKAFMAEIRQYIRELNLIIKVFREPFVSNSKLFSANDVENIFSRIVDIHELSVKLLGHIEDTVEMTDEGSPHPLVGSCFEDLAEELAFDPYESYARDILRPGFHDRFLSQLSKPGAALYLQSIGEGFKEAVQYVLPRLLLAPVYHCLHYFELLKQLEEKSEDQEDKECLKQAITALLNVQSGMEKICSKSLAKRRLSESACRFYSQQMKGKQLAIKKMNEIQKNIDGWEGKDIGQCCNEFIMEGTLTRVGAKHERHIFLFDGLMICCKSNHGQPRLPGASNAEYRLKEKFFMRKVQINDKDDTSEYKHAFEIILKDENSVIFSAKSAEEKNNWMAALISLQYRSTLERMLDVTMLQEEKEEQMRLPSADVYRFAEPDSEENIIFEENVQPKAGIPIIKAGTVIKLIERLTYHMYADPNFVRTFLTTYRSFCKPQELLSLIIERFEIPEPEPTEADRIAIENGDQPLSAELKRFRKEYIQPVQLRVLNVCRHWVEHHFYDFERDADLLQRMEEFIGTVRGKAMKKWVESITKIIQRKKIARDNGPGHNITFQSSPPTVEWHISRPGHIETFDLLTLHPIEIARQLTLLESDLYRAVQPSELVGSVWTKEDKEINSPNLLKMIRHTTNLTLWFEKCIVETENLEERVAVVSRIIEILQVFQELNNFNGVLEVVSAMNSSPVYRLDHTFEQIPSRQKKILEEAHELSEDHYKKYLAKLRSINPPCVPFFGIYLTNILKTEEGNPEVLKRHGKELINFSKRRKVAEITGEIQQYQNQPYCLRVESDIKRFFENLNPMGNSMEKEFTDYLFNKSLEIEPRNPKPLPRFPKKYNYPLKSPGVRPSNPRPGTMRHPTPLQQEPRKISYSRIPESETESTASAPNSPRTPLTPPPASGASSTTDVCSVFDSDHSSPFHSSSDTVFIQVTLPHGPRSASVSSISLTKSTDEVPVPPPVPPRRRPESAPAESSPSKMMSKHLDSPPAIPPRQPTSKAYSPRYSISDRTSISDPPESPPLLPPREPVRTPDVFSSSPLHLQPPPLGKKSDHSNAFFPNSPSPFTPPPPQTPSPHGTRRHLPSPPLTQEVDLHSIAGPPVPPRQSTSQHIPKLPPKTYKREHTHPSMHRDGPPLLENAHSS", "length": 1333, "header": "tr|A0AAA9TIR9-1|F1N7C3_BOVIN Computationally mapped isoform of SOS Ras/Rac guanine nucleotide exchange factor 1 OS=Bos taurus OX=9913 GN=SOS1 PE=4 SV=1 CANONICAL=F1N7C3-1" }, "locus": { "chromosome": "11", "start_pos": 21434854, "end_pos": 21308262, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000118195.1", "url": "https://www.ensembl.org/id/ENSBTAT00000118195.1" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000097037.1", "url": "https://www.ensembl.org/id/ENSBTAP00000097037.1" } ] } }, { "isoform_ac": "A0AAA9TYY7-1", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TYY7/entry", "sequence": { "sequence": "MQAQQLPYEFFSEENAPKWRGLLVPALKKVQGQVHPTLESSDDALQYVEELILQLLNMLCQAQPRSASDVEERVQKSFPHPIDKWAIADAQSAIEKRKRRNPLSLPVEKIHPLLKEVLGYKIDHQVSVYIVAVLEYISADILKLVGNYVRNIRHYEITKQDIKVAMCADKVLMDMFHQDVEDINILSLTDEEPSTSGEQTYYDLVKAFMAEIRQYIRELNLIIKVFREPFVSNSKLFSANDVENIFSRIVDIHELSVKLLGHIEDTVEMTDEGSPHPLVGSCFEDLAESIGEGFKEAVQYVLPRLLLAPVYHCLHYFELLKQLEEKSEDQEDKECLKQAITALLNVQSGMEKICSKSLAKRRLSESACRFYSQQMKGKQLAIKKMNEIQKNIDGWEGKDIGQCCNEFIMEGTLTRVGAKHERHIFLFDGLMICCKSNHGQPRLPGASNAEYRLKEKFFMRKVQINDKDDTSEYKHAFEIILKDENSVIFSAKSAEEKNNWMAALISLQYRSTLERMLDVTMLQEEKEEQMRLPSADVYRFAEPDSEENIIFEENVQPKAGIPIIKAGTVIKLIERLTYHMYADPNFVRTFLTTYRSFCKPQELLSLIIERFEIPEPEPTEADRIAIENGDQPLSAELKRFRKEYIQPVQLRVLNVCRHWVEHHFYDFERDADLLQRMEEFIGTVRGKAMKKWVESITKIIQRKKIARDNGPGHNITFQSSPPTVEWHISRPGHIETFDLLTLHPIEIARQLTLLESDLYRAVQPSELVGSVWTKEDKEINSPNLLKMIRHTTNLTLWFEKCIVETENLEERVAVVSRIIEILQVFQELNNFNGVLEVVSAMNSSPVYRLDHTFEQIPSRQKKILEEAHELSEDHYKKYLAKLRSINPPCVPFFGIYLTNILKTEEGNPEVLKRHGKELINFSKRRKVAEITGEIQQYQNQPYCLRVESDIKRFFENLNPMGNSMEKEFTDYLFNKSLEIEPRNPKPLPRFPKKYNYPLKSPGVRPSNPRPGTMRHPTPLQQEPRKISYSRIPESETESTASAPNSPRTPLTPPPASGASSTTDVCSVFDSDHSSPFHSSSDTVFIQVTLPHGPRSASVSSISLTKSTDEVPVPPPVPPRRRPESAPAESSPSK", "length": 1133, "header": "tr|A0AAA9TYY7-1|A0AAA9TYY7_BOVIN Computationally mapped isoform of SOS Ras/Rac guanine nucleotide exchange factor 1 OS=Bos taurus OX=9913 GN=SOS1 PE=4 SV=1 CANONICAL=F1N7C3-1" }, "locus": { "chromosome": "11", "start_pos": 21434854, "end_pos": 21309668, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000128492.1", "url": "https://www.ensembl.org/id/ENSBTAT00000128492.1" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000101926.1", "url": "https://www.ensembl.org/id/ENSBTAP00000101926.1" } ] } }, { "isoform_ac": "F1N7C3-1", "url": "https://www.uniprot.org/uniprotkb/F1N7C3/entry", "sequence": { "sequence": "MQAQQLPYEFFSEENAPKWRGLLVPALKKVQGQVHPTLESSDDALQYVEELILQLLNMLCQAQPRSASDVEERVQKSFPHPIDKWAIADAQSAIEKRKRRNPLSLPVEKIHPLLKEVLGYKIDHQVSVYIVAVLEYISADILKLVGNYVRNIRHYEITKQDIKVAMCADKVLMDMFHQDVEDINILSLTDEEPSTSGEQTYYDLVKAFMAEIRQYIRELNLIIKVFREPFVSNSKLFSANDVENIFSRIVDIHELSVKLLGHIEDTVEMTDEGSPHPLVGSCFEDLAEELAFDPYESYARDILRPGFHDRFLSQLSKPGAALYLQSIGEGFKEAVQYVLPRLLLAPVYHCLHYFELLKQLEEKSEDQEDKECLKQAITALLNVQSGMEKICSKSLAKRRLSESACRFYSQQMKGKQLAIKKMNEIQKNIDGWEGKDIGQCCNEFIMEGTLTRVGAKHERHIFLFDGLMICCKSNHGQPRLPGASNAEYRLKEKFFMRKVQINDKDDTSEYKHAFEIILKDENSVIFSAKSAEEKNNWMAALISLQYRSTLERMLDVTMLQEEKEEQMRLPSADVYRFAEPDSEENIIFEENVQPKAGIPIIKAGTVIKLIERLTYHMYADPNFVRTFLTTYRSFCKPQELLSLIIERFEIPEPEPTEADRIAIENGDQPLSAELKRFRKEYIQPVQLRVLNVCRHWVEHHFYDFERDADLLQRMEEFIGTVRGKAMKKWVESITKIIQRKKIARDNGPGHNITFQSSPPTVEWHISRPGHIETFDLLTLHPIEIARQLTLLESDLYRAVQPSELVGSVWTKEDKEINSPNLLKMIRHTTNLTLWFEKCIVETENLEERVAVVSRIIEILQVFQELNNFNGVLEVVSAMNSSPVYRLDHTFEQIPSRQKKILEEAHELSEDHYKKYLAKLRSINPPCVPFFGIYLTNILKTEEGNPEVLKRHGKELINFSKRRKVAEITGEIQQYQNQPYCLRVESDIKRFFENLNPMGNSMEKEFTDYLFNKSLEIEPRNPKPLPRFPKKYNYPLKSPGVRPSNPRPGTMRHPTPLQQEPRKISYSRIPESETESTASAPNSPRTPLTPPPASGASSTTDVCSVFDSDHSSPFHSRSASVSSISLTKSTDEVPVPPPVPPRRRPESAPAESSPSKMMSKHLDSPPAIPPRQPTSKAYSPRYSISDRTSISDPPESPPLLPPREPVRTPDVFSSSPLHLQPPPLGKKSDHSNAFFPNSPSPFTPPPPQTPSPHGTRRHLPSPPLTQEVDLHSIAGPPVPPRQSTSQHIPKLPPKTYKREHTHPSMHRDGPPLLENAHSS", "length": 1318, "header": "tr|F1N7C3-1|F1N7C3_BOVIN Isoform 1 of SOS Ras/Rac guanine nucleotide exchange factor 1 OS=Bos taurus OX=9913 GN=SOS1 PE=4 SV=3 CANONICAL=F1N7C3-1" }, "locus": { "chromosome": "11", "start_pos": 21434854, "end_pos": 21308262, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000015471.5", "url": "https://www.ensembl.org/id/ENSBTAT00000015471.5" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000015471.5", "url": "https://www.ensembl.org/id/ENSBTAP00000015471.5" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [ { "id": "bta:537682", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?bta:537682", "resource": "KEGG Pathway" }, { "id": "R-BTA-112412", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-BTA-112412", "resource": "Reactome", "description": "SOS-mediated signalling" }, { "id": "R-BTA-1250347", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-BTA-1250347", "resource": "Reactome", "description": "SHC1 events in ERBB4 signaling" }, { "id": "R-BTA-1433557", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-BTA-1433557", "resource": "Reactome", "description": "Signaling by SCF-KIT" }, { "id": "R-BTA-1433559", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-BTA-1433559", "resource": "Reactome", "description": "Regulation of KIT signaling" }, { "id": "R-BTA-167044", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-BTA-167044", "resource": "Reactome", "description": "Signalling to RAS" }, { "id": "R-BTA-179812", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-BTA-179812", "resource": "Reactome", "description": "GRB2 events in EGFR signaling" }, { "id": "R-BTA-180336", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-BTA-180336", "resource": "Reactome", "description": "SHC1 events in EGFR signaling" }, { "id": "R-BTA-186763", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-BTA-186763", "resource": "Reactome", "description": "Downstream signal transduction" }, { "id": "R-BTA-1963640", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-BTA-1963640", "resource": "Reactome", "description": "GRB2 events in ERBB2 signaling" }, { "id": "R-BTA-210993", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-BTA-210993", "resource": "Reactome", "description": "Tie2 Signaling" }, { "id": "R-BTA-2179392", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-BTA-2179392", "resource": "Reactome", "description": "EGFR Transactivation by Gastrin" }, { "id": "R-BTA-2424491", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-BTA-2424491", "resource": "Reactome", "description": "DAP12 signaling" }, { "id": "R-BTA-2428933", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-BTA-2428933", "resource": "Reactome", "description": "SHC-related events triggered by IGF1R" }, { "id": "R-BTA-2730905", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-BTA-2730905", "resource": "Reactome", "description": "Role of LAT2/NTAL/LAB on calcium mobilization" }, { "id": "R-BTA-2871796", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-BTA-2871796", "resource": "Reactome", "description": "FCERI mediated MAPK activation" }, { "id": "R-BTA-2871809", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-BTA-2871809", "resource": "Reactome", "description": "FCERI mediated Ca+2 mobilization" }, { "id": "R-BTA-354194", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-BTA-354194", "resource": "Reactome", "description": "GRB2:SOS provides linkage to MAPK signaling for Integrins" }, { "id": "R-BTA-375165", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-BTA-375165", "resource": "Reactome", "description": "NCAM signaling for neurite out-growth" }, { "id": "R-BTA-416482", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-BTA-416482", "resource": "Reactome", "description": "G alpha (12/13) signalling events" }, { "id": "R-BTA-5654688", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-BTA-5654688", "resource": "Reactome", "description": "SHC-mediated cascade:FGFR1" }, { "id": "R-BTA-5654693", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-BTA-5654693", "resource": "Reactome", "description": "FRS-mediated FGFR1 signaling" }, { "id": "R-BTA-5654699", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-BTA-5654699", "resource": "Reactome", "description": "SHC-mediated cascade:FGFR2" }, { "id": "R-BTA-5654700", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-BTA-5654700", "resource": "Reactome", "description": "FRS-mediated FGFR2 signaling" }, { "id": "R-BTA-5654704", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-BTA-5654704", "resource": "Reactome", "description": "SHC-mediated cascade:FGFR3" }, { "id": "R-BTA-5654706", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-BTA-5654706", "resource": "Reactome", "description": "FRS-mediated FGFR3 signaling" }, { "id": "R-BTA-5654712", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-BTA-5654712", "resource": "Reactome", "description": "FRS-mediated FGFR4 signaling" }, { "id": "R-BTA-5654719", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-BTA-5654719", "resource": "Reactome", "description": "SHC-mediated cascade:FGFR4" }, { "id": "R-BTA-5673001", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-BTA-5673001", "resource": "Reactome", "description": "RAF/MAP kinase cascade" }, { "id": "R-BTA-74749", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-BTA-74749", "resource": "Reactome", "description": "Signal attenuation" }, { "id": "R-BTA-74751", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-BTA-74751", "resource": "Reactome", 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], "pmid": "" }, { "name": "molecular condensate scaffold activity", "id": "GO:0140693", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0140693", "evidence": [ { "database": "UniProtKB", "id": "F1N7C3", "url": "https://www.uniprot.org/uniprotkb/F1N7C3" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 11, "go_terms": [ { "name": "small GTPase-mediated signal transduction", "id": "GO:0007264", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007264", "evidence": [ { "database": "UniProtKB", "id": "F1N7C3", "url": "https://www.uniprot.org/uniprotkb/F1N7C3" } ], "pmid": "" }, { "name": "regulation of transcription by RNA polymerase II", "id": "GO:0006357", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006357", "evidence": [ { "database": "UniProtKB", "id": "F1N7C3", "url": "https://www.uniprot.org/uniprotkb/F1N7C3" } ], "pmid": "" }, { "name": "regulation of cell population proliferation", "id": "GO:0042127", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0042127", "evidence": [ { "database": "UniProtKB", "id": "F1N7C3", "url": "https://www.uniprot.org/uniprotkb/F1N7C3" } ], "pmid": "" }, { "name": "T cell activation", "id": "GO:0042110", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0042110", "evidence": [ { "database": "UniProtKB", "id": "F1N7C3", "url": "https://www.uniprot.org/uniprotkb/F1N7C3" } ], "pmid": "" }, { "name": "myelination", "id": "GO:0042552", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0042552", "evidence": [ { "database": "UniProtKB", "id": "F1N7C3", "url": "https://www.uniprot.org/uniprotkb/F1N7C3" } ], "pmid": "" }, { "name": "Ras protein signal transduction", "id": "GO:0007265", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007265", "evidence": [ { "database": "UniProtKB", "id": "F1N7C3", "url": "https://www.uniprot.org/uniprotkb/F1N7C3" } ], "pmid": "" }, { "name": "epidermal growth factor receptor signaling pathway", "id": "GO:0007173", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007173", "evidence": [ { "database": 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74, "header": "tr|A0AAA9SXM0-1|F6QLU0_BOVIN Computationally mapped isoform of Transmembrane protein 107 OS=Bos taurus OX=9913 GN=TMEM107 PE=4 SV=1 CANONICAL=F6QLU0-1" }, "locus": { "chromosome": "19", "start_pos": 27823511, "end_pos": 27821670, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000093579.1", "url": "https://www.ensembl.org/id/ENSBTAT00000093579.1" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000090106.1", "url": "https://www.ensembl.org/id/ENSBTAP00000090106.1" } ] } }, { "isoform_ac": "F6QLU0-1", "url": "https://www.uniprot.org/uniprotkb/F6QLU0/entry", "sequence": { "sequence": "SGGDCGVRRVILGKVAGAGAQAAPGVGIPGGASVRVSVRQCCVGRLGNVGPRHNTLSGCADSSSARGKADGSILCIRSGSAQDSNIQACLPLKFTPEEYEKQDIQLVAALSVTLALFAVELAGFFLGVSMFNSTQSLISIGAHCGASVALSFFIFERWECTTYWYIFVFCSALPAVTEITLFISVFGLKKKPF", "length": 193, "header": "tr|F6QLU0-1|F6QLU0_BOVIN Isoform 1 of Transmembrane protein 107 OS=Bos taurus OX=9913 GN=TMEM107 PE=4 SV=1 CANONICAL=F6QLU0-1" }, "locus": { "chromosome": "19", "start_pos": 27824023, "end_pos": 27821670, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000002231.6", "url": "https://www.ensembl.org/id/ENSBTAT00000002231.6" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000002231.5", "url": "https://www.ensembl.org/id/ENSBTAP00000002231.5" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [], "orthologs": [], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 2, "go_terms": [ { "name": "membrane", "id": "GO:0016020", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016020", "evidence": [ { "database": "UniProtKB", "id": "F6QLU0", "url": "https://www.uniprot.org/uniprotkb/F6QLU0" } ], "pmid": "" }, { "name": "MKS complex", "id": "GO:0036038", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0036038", "evidence": [ { "database": "UniProtKB", "id": "F6QLU0", "url": "https://www.uniprot.org/uniprotkb/F6QLU0" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 5, "go_terms": [ { "name": "cell projection organization", "id": "GO:0030030", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030030", "evidence": [ { "database": "UniProtKB", "id": "F6QLU0", "url": "https://www.uniprot.org/uniprotkb/F6QLU0" } ], "pmid": "" }, { "name": "embryonic digit morphogenesis", "id": "GO:0042733", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0042733", "evidence": [ { "database": "UniProtKB", "id": "F6QLU0", "url": "https://www.uniprot.org/uniprotkb/F6QLU0" } ], "pmid": "" }, { "name": "neural tube patterning", "id": "GO:0021532", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0021532", "evidence": [ { "database": "UniProtKB", "id": "F6QLU0", "url": "https://www.uniprot.org/uniprotkb/F6QLU0" } ], "pmid": "" }, { "name": "non-motile cilium assembly", "id": "GO:1905515", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:1905515", "evidence": [ { "database": "UniProtKB", "id": "F6QLU0", "url": "https://www.uniprot.org/uniprotkb/F6QLU0" } ], "pmid": "" }, { "name": "protein localization to ciliary transition zone", "id": "GO:1904491", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:1904491", "evidence": [ { "database": "UniProtKB", "id": "F6QLU0", "url": "https://www.uniprot.org/uniprotkb/F6QLU0" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 132, "end_pos": 134, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 132, "end_pos": 134 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ], "tool_support": { "graph_view": "yes" } }, { "uniprot_canonical_ac": "F1N4N5-1", "uniprot_ac": "F1N4N5", "uniprot_id": "F1N4N5_BOVIN", "mass": { "chemical_mass": 42380.0, "monoisotopic_mass": 42380.0 }, "refseq": { "ac": "XP_024853774", "name": "protein FAM81A isoform X2", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_024853774" }, "gene_names": [ { "name": "FAM81A", "type": "recommended", "evidence": [ { "id": "F1N4N5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1N4N5" } ] }, { "name": "FAM81A", "type": "synonym", "evidence": [ { "id": "XP_024853774", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_024853774" } ] } ], "protein_names": [ { "name": "Family with sequence similarity 81 member A", "type": "synonym", "evidence": [ { "id": "F1N4N5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1N4N5/entry#names_and_taxonomy" } ] }, { "name": "protein FAM81A isoform X2", "type": "synonym", "evidence": [ { "id": "XP_024853774", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_024853774" } ] } ], "function": [], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Bos taurus", "taxid": 9913, "evidence": [ { "database": "UniProtKB", "id": "F1N4N5", "url": "https://www.uniprot.org/uniprotkb/F1N4N5" } ], "common_name": "Bovine", "glygen_name": "Bovine", "reference_species": "Bos taurus [9913]" } ], "gene": [ { "name": "FAM81A", "url": "https://www.uniprot.org/uniprotkb/F1N4N5", "locus": { "chromosome": "10", "start_pos": 50799242, "end_pos": 50891915, "strand": "+", "evidence": [ { "database": "Ensembl Gene", "id": "ENSBTAG00000014699", "url": "https://www.ensembl.org/id/ENSBTAG00000014699" } ] } } ], "crossref": [ { "id": "F1N4N5", "url": "https://alphafold.ebi.ac.uk/entry/F1N4N5", "database": "AlphaFoldDB", "categories": [] }, { "id": "ENSBTAG00000014699", "url": "https://bgee.org/?page=gene&gene_id=ENSBTAG00000014699", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "538402", "url": "https://www.ncbi.nlm.nih.gov/gene/538402", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR029619", "url": "https://www.ebi.ac.uk/interpro/entry/IPR029619", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "MQKITME", "url": "https://omabrowser.org/oma/group/MQKITME/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "PTHR22420", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR22420", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR22420:SF2", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR22420:SF2", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF28217", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF28217", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "XP_024853774", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_024853774", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0AAA9SDN8", "url": "https://www.uniprot.org/uniprotkb/A0AAA9SDN8", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0AAA9SDN8-1", "url": "https://www.uniprot.org/uniprotkb/A0AAA9SDN8-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "F1N4N5", "url": "https://www.uniprot.org/uniprotkb/F1N4N5", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "F1N4N5-1", "url": "https://www.uniprot.org/uniprotkb/F1N4N5-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MENMHLRRVRTMPRHSQSLTMAPYSSVSLVEQLEDRILCHEKTTAALVEHAFRIKDDIVSSLQKMQNKGGGDRLARLFLEEHIRNITAIVKQLNRDIEVLQEQIRARDNISYGTNSALKTLEMRQLSGLGDLRGRVARCDASIARLSAEHKTTYEGLQHLNKEQQAAKLILETKIKDAEGQISQLLNRVDLSISEQSTKLKMSHRDSNHQLQLLDTKFKGTIEELSNQILSARNWLQQEQERIEKELLQKIDQLSLVVKENSGASERDMEKKLSQMSARLDKIEESQKKNMEVQRTKQEEEKVHGRISKLELQMTEDMKEMKAEVDAGFTAIYESIGSLRQVLEAKMKLDKDQLQKQIQQMQKPEAPM", "length": 368, "header": "tr|F1N4N5-1|F1N4N5_BOVIN Isoform 1 of Family with sequence similarity 81 member A OS=Bos taurus OX=9913 GN=FAM81A PE=3 SV=3 CANONICAL=F1N4N5-1" }, "isoforms": [ { "isoform_ac": "A0AAA9SDN8-1", "url": "https://www.uniprot.org/uniprotkb/A0AAA9SDN8/entry", "sequence": { "sequence": "MENMHLRRVRTMPRHSQSLTMAPYSSVSLVEQLEDRILCHEKTTAALVEHAFRIKDDIVSSLQKMQNKGGGDRLARLFLEEHIRNITAIVKQLNRDIEVLQEQIRARDNISYGTNSALKTLEMRQLSGLGDLRGRVARCDASIARLSAEHKTTYEGLQHLNKEQQAAKLILETKIKDAEGQISQLLNRVDLSISEQSTKLKMSHRDSNHQLQLLDTKFKGTIEELSNQILSARNWLQQEQERIEKELLQKIDQLSLVVKENSGASERDMEKKLSQMSARLDKIEESQKKNMEVQRTKQEEEKVHGRISKLELQMTEDMKEMKAEVDADEKTESRKGEATSPKSCG", "length": 345, "header": "tr|A0AAA9SDN8-1|F1N4N5_BOVIN Computationally mapped isoform of Family with sequence similarity 81 member A OS=Bos taurus OX=9913 GN=FAM81A PE=3 SV=1 CANONICAL=F1N4N5-1" }, "locus": { "chromosome": "10", "start_pos": 50869168, "end_pos": 50805773, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000113669.1", "url": "https://www.ensembl.org/id/ENSBTAT00000113669.1" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000084256.1", "url": "https://www.ensembl.org/id/ENSBTAP00000084256.1" } ] } }, { "isoform_ac": "F1N4N5-1", "url": "https://www.uniprot.org/uniprotkb/F1N4N5/entry", "sequence": { "sequence": "MENMHLRRVRTMPRHSQSLTMAPYSSVSLVEQLEDRILCHEKTTAALVEHAFRIKDDIVSSLQKMQNKGGGDRLARLFLEEHIRNITAIVKQLNRDIEVLQEQIRARDNISYGTNSALKTLEMRQLSGLGDLRGRVARCDASIARLSAEHKTTYEGLQHLNKEQQAAKLILETKIKDAEGQISQLLNRVDLSISEQSTKLKMSHRDSNHQLQLLDTKFKGTIEELSNQILSARNWLQQEQERIEKELLQKIDQLSLVVKENSGASERDMEKKLSQMSARLDKIEESQKKNMEVQRTKQEEEKVHGRISKLELQMTEDMKEMKAEVDAGFTAIYESIGSLRQVLEAKMKLDKDQLQKQIQQMQKPEAPM", "length": 368, "header": "tr|F1N4N5-1|F1N4N5_BOVIN Isoform 1 of Family with sequence similarity 81 member A OS=Bos taurus OX=9913 GN=FAM81A PE=3 SV=3 CANONICAL=F1N4N5-1" }, "locus": { "chromosome": "10", "start_pos": 50869168, "end_pos": 50808339, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000019564.7", "url": "https://www.ensembl.org/id/ENSBTAT00000019564.7" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000019564.6", "url": "https://www.ensembl.org/id/ENSBTAP00000019564.6" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [], "orthologs": [ { "uniprot_canonical_ac": "A0A8C2N1W8-1", "protein_name": "Protein FAM81A", "gene_name": "Fam81a", "tax_id": 10029, "organism": "Cricetulus griseus", "sequence": { "sequence": "MHLRRVRTMPRHSQSLTMAPYSSVSLVEQLEDRILCHEKTTAALVEHAFRIKDDIVSSLQKMQNKGGGDRLARLFLEEHIRNITAIVKQLNRDIEVLQEQIRARDNISYGTNSALKTLEMRQLSGLGDLRGRVARCDASIARLSAEHKTTYEGLQHLNKEQQAAKLILETKIKDAEGQISQLLSRVDLSISEQSTKLKMSHRDSNHQLQLLDTKFKGTVEELSNQILSARSWLQQEQERIEKELLQKIDHLSLIVKENSGASERDMEKKLSQMSARLDKIEESQKKNVEGQRGKPEEEKVHGRISKLELQMSEDMKEMKAEVNAGFTAIYESIGSLRQVLEAKMKLDRDQLQKQIQQMQKPETSM", "length": 365 }, "evidence": [ { "id": "F1N4N5", "url": "https://omabrowser.org/oma/group/F1N4N5/", "database": "OMA" } ], "glygen_name": "Hamster", "common_name": "Chinese hamster" }, { "uniprot_canonical_ac": "A0A8V0ZXT3-1", "protein_name": "Family with sequence similarity 81 member A", "gene_name": "FAM81A", "tax_id": 9031, "organism": "Gallus gallus", "sequence": { "sequence": "MKRHKLLTRKWPNEAQSSQPSPILKASLNCRKKSLTCLCMDRGSSKQQPFICSSRPLRVRNIPLHSQALTAVPLASASLVDQLEDRILSHEKTTAALVEHAFRIKEDIVSTLHRMQNKGGGDRLARQLLEEHIRNITAIVRQLNRDIEMLQEQIRVRDNLSYGTNSTLKSLEMRQLSGLGDLRGRVARCDAGLARLSAEHKITYERLQSLTKDQHTSKLILESKIKETEIQVSHLLSRVEQAVAQQEAKLKLAYKESAQQLHLLDTKLKNAIEELSSQILSARSWLEQEHERIEKELVQKLDQLSLTFKENTEMSERATEMKFNQMSEKINKIEEIQKISMEAHETQQTEEKINIRIGKLQNEINEDIKEMKAEVNAGFAAIYESIGSLRQVLEAKMKLDRDELQKQIHQMKQEVPMWGEAGP", "length": 423 }, "evidence": [ { "id": "F1N4N5", "url": "https://omabrowser.org/oma/group/F1N4N5/", "database": "OMA" } ], "glygen_name": "Chicken", "common_name": "Chicken" }, { "uniprot_canonical_ac": "D4A7T8-1", "protein_name": "Protein FAM81A", "gene_name": "Fam81a", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MHLRRVRTMPRHSQSLTMAPYSSVSLVEQLEDRILCHEKTTAALVEHAFRIKDDIVSSLQKMQNKGGGDRLARLFLEEHIRNITAIVKQLNRDIEVLQEQIRARDNISYGTNSALKTLEMRQLSGLGDLRGRVARCDASIARLSAEHKTTYEGLQHLNKEQQAAKLILETKIKDAEGQISQLLNRVDLSISEQSTKLKMSHRDSNHQLQLLDTKFKGTVEELSNQILSARSWLQQEQERIEKELLQKIDHLSLIVKENSGASERDMEKKLTQMSARLDKIEESQRRNAEGQRKPEEEKVHGRISKLELQMTEDMKEMKAEVNAGFTAIYESIGSLRQVLEAKMKLDRDQLQKQIQQMQKPESSM", "length": 364 }, "evidence": [ { "id": "F1N4N5", "url": "https://omabrowser.org/oma/group/F1N4N5/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "Q3UXZ6-1", "protein_name": "Protein FAM81A", "gene_name": "Fam81a", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MHLRRVKTMPRHSQSLTMAPYSSVSLVEQLEDRILCHEKTTAALVEHAFRIKDDIVSSLQKMQNKGGGDRLARLFLEEHIRNITAIVKQLNRDIEVLQEQIRARDNISYGTNSALKTLEMRQLSGLGDLRGRVARCDASIARLSAEHKSTYEGLQHLNKEQQAAKLILETKIKDAEGQISQLLSRVDLSISEQSTKLKMSHRDSNHQLQLLDTKFKGTVEELSNQILSARSWLQQEQERIEKELLQKIDHLSLIVKENSGANERDVEKKLSQMSARLDKIEESQKRNAEGQRKPDEEKVHGRISKLELQMTEDMKEMKAEVNAGFSAIYESIGSLRQVLEAKMKLDRDQLQKQIQQMQKPETAM", "length": 364 }, "evidence": [ { "id": "F1N4N5", "url": "https://omabrowser.org/oma/group/F1N4N5/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q8TBF8-1", "protein_name": "Protein FAM81A", "gene_name": "FAM81A", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MENMHLRRVRTMPRHSQSLTMAPYSSVSLVEQLEDRILCHEKTTAALVEHAFRIKDDIVNSLQKMQNKGGGDRLARLFLEEHIRNITAIVKQLNRDIEVLQEQIRARDNISYGTNSALKTLEMRQLSGLGDLRGRVARCDASIARLSAEHKTTYEGLQHLNKEQQAAKLILETKIKDAEGQISQLLNRVDLSISEQSTKLKMSHRDSNHQLQLLDTKFKGTVEELSNQILSARSWLQQEQERIEKELLQKIDQLSLIVKENSGASERDMEKKLSQMSARLDKIEEGQKKTFDGQRTRQEEEKMHGRITKLELQMNQNIKEMKAEVNAGFTAVYESIGSLRQVLEAKMKLDRDQLQKQIQLMQKPETPM", "length": 368 }, "evidence": [ { "id": "F1N4N5", "url": "https://omabrowser.org/oma/group/F1N4N5/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" } ], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 2, "go_terms": [ { "name": "cytoplasm", "id": "GO:0005737", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005737", "evidence": [ { "database": "UniProtKB", "id": "F1N4N5", "url": "https://www.uniprot.org/uniprotkb/F1N4N5" } ], "pmid": "" }, { "name": "postsynaptic density", "id": "GO:0014069", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0014069", "evidence": [ { 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] }, { "name": "Histone-arginine N-methyltransferase PRMT2", "type": "synonym", "evidence": [ { "id": "F6R040", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F6R040/entry#names_and_taxonomy" } ] } ], "function": [], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Bos taurus", "taxid": 9913, "evidence": [ { "database": "UniProtKB", "id": "F6R040", "url": "https://www.uniprot.org/uniprotkb/F6R040" } ], "common_name": "Bovine", "glygen_name": "Bovine", "reference_species": "Bos taurus [9913]" } ], "gene": [ { "name": "PRMT2", "url": "https://www.uniprot.org/uniprotkb/F6R040", "locus": { "chromosome": "1", "start_pos": 146345138, "end_pos": 146319877, "strand": "-", "evidence": [ { "database": "Ensembl Gene", "id": "ENSBTAG00000005503", "url": "https://www.ensembl.org/id/ENSBTAG00000005503" } ] } } ], "crossref": [ { "id": "F6R040", "url": "https://alphafold.ebi.ac.uk/entry/F6R040", "database": 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[ { "isoform_ac": "A0AAA9SIG7-1", "url": "https://www.uniprot.org/uniprotkb/A0AAA9SIG7/entry", "sequence": { "sequence": "MATPGDCPRNELQEEEDPTTQAEEEHLQGAVHPEEFVAIADYSATDETQLSFLRGEKILILRQTTADWWWGERAGCCGYIPANHLGKQLEDWDPEDSWQDEEYFGSYGTLKLHLEMLADQPRTTKYHSVILQNKESLKDKVILDVGCGTGIISLFCAHYAQPRAVFAVEASEMAQHTGQLVVQNGFADIITVFQQKVEDVVLPEKVDVLVSEWMGTCLLVGEKVFPIWR", "length": 229, "header": "tr|A0AAA9SIG7-1|F6R040_BOVIN Computationally mapped isoform of Protein arginine N-methyltransferase 2 OS=Bos taurus OX=9913 GN=PRMT2 PE=4 SV=2 CANONICAL=F6R040-1" }, "locus": { "chromosome": "1", "start_pos": 146344517, "end_pos": 146321575, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000088516.2", "url": "https://www.ensembl.org/id/ENSBTAT00000088516.2" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000086041.2", "url": "https://www.ensembl.org/id/ENSBTAP00000086041.2" } ] } }, { "isoform_ac": "F6QJ60-1", "url": "https://www.uniprot.org/uniprotkb/F6QJ60/entry", "sequence": { "sequence": "MRASARRLRSSGRWLTLPTRGVGVDGGACSRSRFQGGAFHGGVGGGQCVHRAPARAEGGGLFLGGCWLPLLSGGVDADLSGETQLRNEGENETLKQQLCTDPKGTMATPGDCPRNELQEEEDPTTQAEEEHLQGAVHPEEFVAIADYSATDETQLSFLRGEKILILRQTTADWWWGERAGCCGYIPANHLGKQLEDWDPEDSWQDEEYFGSYGTLKLHLEMLADQPRTTKYHSVILQNKESLKDKVILDVGCGTGIISLFCAHYAQPRAVFAVEASEMAQHTGQLVVQNGFADIITVFQQKVEDVVLPEKVDVLVSEWMGTCLLFEFMIESILYARDAWLKEDGIIWPTTAALHLVPCSADKDYRSKVLFWDNAYEFDLSPLKSLAIKEFFSKPKYNHILKPDDCLSEPCTILQLDMRTVQVADLEMMKGELHFDIQKAGMLHGFTAWFSVQFQNLEEDEPQLVLSTGPLHPTTHWKQVLFMMDEPVPVLVGDMVTGAVVLQRNPVWRRHMSVTLSWSITSAQDPTLQKVGEKVFPIWR", "length": 539, "header": "tr|F6QJ60-1|F6QJ60_BOVIN Computationally mapped isoform of Protein arginine N-methyltransferase 2 OS=Bos taurus OX=9913 GN=PRMT2 PE=4 SV=1 CANONICAL=F6R040-1" }, "locus": { "chromosome": "1", "start_pos": 146344517, "end_pos": 146320076, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000007234.8", "url": "https://www.ensembl.org/id/ENSBTAT00000007234.8" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000007234.6", "url": "https://www.ensembl.org/id/ENSBTAP00000007234.6" } ] } }, { "isoform_ac": "F6R040-1", "url": "https://www.uniprot.org/uniprotkb/F6R040/entry", "sequence": { "sequence": "MRASARRLRSSGRWLTLPTRGVGVDGGACSRSRFQGGAFHGGVGGGQCVHRAPARAEGGGLFLGGCWLPLLSGGVDADLSGETQLRNEGENETLKQQLCTDPKGTMATPGDCPRNELQEEEDPTTQAEEEHLQGAVHPEEFVAIADYSATDETQLSFLRGEKILILRQTTADWWWGERAGCCGYIPANHLGKQLEDWDPEDSWQDEEYFGSYGTLKLHLEMLADQPRTTKYHSVILQNKESLKDKVILDVGCGTGIISLFCAHYAQPRAVFAVEASEMAQHTGQLVVQNGFADIITVFQQKVEDVVLPEKVDVLVSEWMGTCLLFEFMIESILYARDAWLKEDGIIWPTTAALHLVPCSADKDYRSKVLFWDNAYEFDLSPLKSLAIKEFFSKPKYNHILKPDDCLSEPCTILQLDMRTVQVADLEMMKGELHFDIQKAGMLHGFTAWFSVQFQNLEEDEPQLVLSTGPLHPLGRKSFPSGDDRAALWGMSTASWGTYVTPRSHSWTDACPGKAMDLLQVGVVTPSRTGSGLQGPPHMPGAGGPPSPLSLPCLS", "length": 554, "header": "tr|F6R040-1|F6R040_BOVIN Isoform 1 of Protein arginine N-methyltransferase 2 OS=Bos taurus OX=9913 GN=PRMT2 PE=4 SV=1 CANONICAL=F6R040-1" }, "locus": { "chromosome": "1", "start_pos": 146344734, "end_pos": 146320076, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000031549.5", "url": "https://www.ensembl.org/id/ENSBTAT00000031549.5" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000031502.4", "url": "https://www.ensembl.org/id/ENSBTAP00000031502.4" } ] } }, { "isoform_ac": "F6R054-1", "url": "https://www.uniprot.org/uniprotkb/F6R054/entry", "sequence": { "sequence": "MATPGDCPRNELQEEEDPTTQAEEEHLQGAVHPEEFVAIADYSATDETQLSFLRGEKILILRQTTADWWWGERAGCCGYIPANHLGKQLEDWDPEDSWQDEEYFGSYGTLKLHLEMLADQPRTTKYHSVILQNKESLKDKVILDVGCGTGIISLFCAHYAQPRAVFAVEASEMAQHTGQLVVQNGFADIITVFQQKVEDVVLPEKVDVLVSEWMGTCLLMMKGELHFDIQKAGMLHGFTAWFSVQFQNLEEDEPQLVLSTGPLHPTTHWKQVLFMMDEPVPVLVGDMVTGAVVLQRNPVWRRHMSVTLSWSITSAQDPTLQKVGEKVFPIWR", "length": 332, "header": "tr|F6R054-1|F6R054_BOVIN Computationally mapped isoform of Protein arginine N-methyltransferase 2 OS=Bos taurus OX=9913 GN=PRMT2 PE=4 SV=2 CANONICAL=F6R040-1" }, "locus": { "chromosome": "1", "start_pos": 146344517, "end_pos": 146321575, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000031548.7", "url": "https://www.ensembl.org/id/ENSBTAT00000031548.7" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000031501.6", "url": "https://www.ensembl.org/id/ENSBTAP00000031501.6" } ] } } ], "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "other", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 108, "start_aa": "Thr", "end_pos": 108, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr108", "evidence": [ { "id": "", "database": "GlyGen", "url": "https://data.glygen.org/" } ], "filter_code": "000000000000000010000.00000000001000.0.01000" }, { "glytoucan_ac": "", "type": "O-linked", "subtype": "other", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 500, "start_aa": "Thr", "end_pos": 500, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr500", "evidence": [ { "id": "", "database": "GlyGen", "url": "https://data.glygen.org/" } ], "filter_code": "000000000000000010000.00000000001000.0.01000" } ], "phosphorylation": [], "glycation": [], "keywords": [ "enzyme", "glycoprotein", "glycoprotein_predicted" ], "publication": [], "pathway": [], "orthologs": [], "go_annotation": { "categories": [ { "name": "Molecular Function", "total": 3, "go_terms": [ { "name": "protein-arginine N-methyltransferase activity", "id": "GO:0016274", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016274", "evidence": [ { "database": "UniProtKB", "id": "F6R040", "url": "https://www.uniprot.org/uniprotkb/F6R040" } ], "pmid": "" }, { "name": "protein-arginine omega-N asymmetric methyltransferase activity", "id": "GO:0035242", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0035242", "evidence": [ { "database": "UniProtKB", "id": "F6R040", "url": "https://www.uniprot.org/uniprotkb/F6R040" } ], "pmid": "" }, { "name": "histone methyltransferase activity", "id": "GO:0042054", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0042054", "evidence": [ { "database": "UniProtKB", "id": "F6R040", "url": "https://www.uniprot.org/uniprotkb/F6R040" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 1, "go_terms": [ { "name": "methylation", "id": "GO:0032259", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0032259", "evidence": [ { "database": "UniProtKB", "id": "F6R040", "url": "https://www.uniprot.org/uniprotkb/F6R040" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 2, "go_terms": [ { "name": "nucleus", "id": "GO:0005634", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005634", "evidence": [ { "database": "UniProtKB", "id": "F6R040", "url": "https://www.uniprot.org/uniprotkb/F6R040" } ], "pmid": "" }, { "name": "cytoplasm", "id": "GO:0005737", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005737", "evidence": [ { "database": "UniProtKB", "id": "F6R040", "url": "https://www.uniprot.org/uniprotkb/F6R040" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 91, "end_pos": 93, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [ { "id": "48096", "name": "", "equation": "L-arginyl-[protein] + 2 S-adenosyl-L-methionine = N(omega),N(omega)-dimethyl-L-arginyl-[protein] + 2 S-adenosyl-L-homocysteine + 2 H(+)", "summary": "", "cellular_location": "", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [ "A0ABZ3NNC5-1", "A0A3Q1MWG1-1", "Q5E9L5-1", "F1MEB9-1", "F1MQ97-1", "F6R040-1" ], "evidence": [ { "id": "48096", "database": "Rhea", "url": "https://www.rhea-db.org/rhea/48096" } ] } ], "reaction_participants": [], "reaction_enzymes": [ { "uniprot_ac": "A0A3Q1MWG1", "gene_name": "CARM1", "activity": [ { "ec_number": "2.1.1.319", "activity": "L-arginyl-[protein] + 2 S-adenosyl-L-methionine = N(omega),N(omega)-dimethyl-L-arginyl-[protein] + 2 S-adenosyl-L-homocysteine + 2 H(+).", "evidence": [ { "id": "A0A3Q1MWG1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1MWG1" } ] }, { "ec_number": "2.1.1.319", "activity": "", "evidence": [ { "id": "A0A3Q1MWG1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1MWG1" } ] } ] }, { "uniprot_ac": "A0ABZ3NNC5", "gene_name": "PRMT1", "activity": [ { "ec_number": "2.1.1.319", "activity": "L-arginyl-[protein] + 2 S-adenosyl-L-methionine = N(omega),N(omega)-dimethyl-L-arginyl-[protein] + 2 S-adenosyl-L-homocysteine + 2 H(+).", "evidence": [ { "id": "A0ABZ3NNC5", "database": "UniProtKB", "url": 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"+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000011469.5", "url": "https://www.ensembl.org/id/ENSBTAT00000011469.5" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000011469.4", "url": "https://www.ensembl.org/id/ENSBTAP00000011469.4" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [ "enzyme" ], "publication": [], "pathway": [], "orthologs": [], "go_annotation": { "categories": [ { "name": "Molecular Function", "total": 6, "go_terms": [ { "name": "protein serine/threonine kinase activity", "id": "GO:0004674", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0004674", "evidence": [ { "database": "UniProtKB", "id": "F6Q5B6", "url": "https://www.uniprot.org/uniprotkb/F6Q5B6" } ], "pmid": "" }, { "name": "non-membrane spanning protein tyrosine kinase activity", "id": "GO:0004715", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0004715", "evidence": [ { "database": "UniProtKB", "id": "F6Q5B6", "url": 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"https://www.uniprot.org/uniprotkb/F6Q5B6" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 3, "go_terms": [ { "name": "nucleus", "id": "GO:0005634", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005634", "evidence": [ { "database": "UniProtKB", "id": "F6Q5B6", "url": "https://www.uniprot.org/uniprotkb/F6Q5B6" } ], "pmid": "" }, { "name": "perinuclear region of cytoplasm", "id": "GO:0048471", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0048471", "evidence": [ { "database": "UniProtKB", "id": "F6Q5B6", "url": "https://www.uniprot.org/uniprotkb/F6Q5B6" } ], "pmid": "" }, { "name": "cytosol", "id": "GO:0005829", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005829", "evidence": [ { "database": "UniProtKB", "id": "F6Q5B6", "url": "https://www.uniprot.org/uniprotkb/F6Q5B6" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 16, "go_terms": [ { "name": "DNA-templated transcription", "id": "GO:0006351", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006351", "evidence": [ { "database": "UniProtKB", "id": "F6Q5B6", "url": "https://www.uniprot.org/uniprotkb/F6Q5B6" } ], "pmid": "" }, { "name": "innate immune response", "id": "GO:0045087", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0045087", "evidence": [ { "database": "UniProtKB", "id": "F6Q5B6", "url": "https://www.uniprot.org/uniprotkb/F6Q5B6" } ], "pmid": "" }, { "name": "defense response to virus", "id": "GO:0051607", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0051607", "evidence": [ { "database": "UniProtKB", "id": "F6Q5B6", "url": "https://www.uniprot.org/uniprotkb/F6Q5B6" } ], "pmid": "" }, { "name": "regulation of NLRP3 inflammasome complex assembly", "id": "GO:1900225", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:1900225", "evidence": [ { "database": "UniProtKB", "id": "F6Q5B6", "url": "https://www.uniprot.org/uniprotkb/F6Q5B6" } ], "pmid": "" }, { "name": "positive regulation of non-canonical NF-kappaB signal transduction", "id": "GO:1901224", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:1901224", "evidence": [ { "database": "UniProtKB", "id": "F6Q5B6", "url": "https://www.uniprot.org/uniprotkb/F6Q5B6" } ], "pmid": "" }, { "name": "positive regulation of chemokine production", "id": "GO:0032722", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0032722", "evidence": [ { "database": "UniProtKB", "id": "F6Q5B6", "url": "https://www.uniprot.org/uniprotkb/F6Q5B6" } ], "pmid": "" }, { "name": "negative regulation of viral genome replication", "id": "GO:0045071", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0045071", "evidence": [ { "database": "UniProtKB", "id": "F6Q5B6", "url": "https://www.uniprot.org/uniprotkb/F6Q5B6" } ], "pmid": "" }, { "name": "regulation of hematopoietic stem cell proliferation", "id": "GO:1902033", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:1902033", "evidence": [ { "database": "UniProtKB", "id": "F6Q5B6", "url": "https://www.uniprot.org/uniprotkb/F6Q5B6" } ], "pmid": "" }, { "name": "positive regulation of 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"https://www.uniprot.org/uniprotkb/F6Q5B6" } ], "pmid": "" }, { "name": "response to interferon-alpha", "id": "GO:0035455", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0035455", "evidence": [ { "database": "UniProtKB", "id": "F6Q5B6", "url": "https://www.uniprot.org/uniprotkb/F6Q5B6" } ], "pmid": "" }, { "name": "positive regulation of stress-activated MAPK cascade", "id": "GO:0032874", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0032874", "evidence": [ { "database": "UniProtKB", "id": "F6Q5B6", "url": "https://www.uniprot.org/uniprotkb/F6Q5B6" } ], "pmid": "" }, { "name": "negative regulation of cytoplasmic translation", "id": "GO:2000766", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:2000766", "evidence": [ { "database": "UniProtKB", "id": "F6Q5B6", "url": "https://www.uniprot.org/uniprotkb/F6Q5B6" } ], "pmid": "" }, { "name": "antiviral innate immune response", "id": "GO:0140374", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0140374", "evidence": [ { "database": "UniProtKB", "id": "F6Q5B6", "url": "https://www.uniprot.org/uniprotkb/F6Q5B6" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 204, "end_pos": 206, "annotation": "n_glycosylation_sequon" }, { "start_pos": 211, "end_pos": 213, "annotation": "n_glycosylation_sequon" }, { "start_pos": 217, "end_pos": 219, "annotation": "n_glycosylation_sequon" }, { "start_pos": 229, "end_pos": 231, "annotation": "n_glycosylation_sequon" }, { "start_pos": 335, "end_pos": 337, "annotation": "n_glycosylation_sequon" }, { "start_pos": 528, "end_pos": 530, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [ { "id": "17989", "name": "", "equation": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+)", "summary": "", "cellular_location": "", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [ "G5E5K2-1", "V6F977-1", "A0A3Q1MRW3-1", "A0A3Q1N860-1", "E1BI01-1", "F6RG88-1", "A0AAA9T8T9-1", 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"database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9RSQ6" } ] } ] }, { "uniprot_ac": "A0AAA9RTJ4", "gene_name": "PIKFYVE", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0AAA9RTJ4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9RTJ4" } ] }, { "ec_number": "2.7.1.150", "activity": "a 1,2-diacyl-sn-glycero-3-phospho-(1D-myo-inositol-3-phosphate) + ATP = a 1,2-diacyl-sn-glycero-3-phospho-(1D-myo-inositol-3,5-bisphosphate) + ADP + H(+).", "evidence": [ { "id": "A0AAA9RTJ4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9RTJ4" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0AAA9RTJ4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9RTJ4" } ] }, { "ec_number": "2.7.1.150", "activity": "", "evidence": [ { "id": "A0AAA9RTJ4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9RTJ4" } ] } ] }, { "uniprot_ac": "A0AAA9RVB1", "gene_name": "TAOK2", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0AAA9RVB1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9RVB1" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0AAA9RVB1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9RVB1" } ] } ] }, { "uniprot_ac": "A0AAA9RW51", "gene_name": "AATK", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0AAA9RW51", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9RW51" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0AAA9RW51", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9RW51" } ] } ] }, { "uniprot_ac": "A0AAA9RWB8", "gene_name": "TRIO", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0AAA9RWB8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9RWB8" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0AAA9RWB8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9RWB8" } ] } ] }, { "uniprot_ac": "A0AAA9RWC6", "gene_name": "CHEK2", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0AAA9RWC6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9RWC6" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0AAA9RWC6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9RWC6" } ] } ] }, { "uniprot_ac": "A0AAA9S2N3", "gene_name": "CDKL4", "activity": [ { "ec_number": "2.7.11.22", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0AAA9S2N3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9S2N3" } ] }, { "ec_number": "2.7.11.22", "activity": "", "evidence": [ { "id": "A0AAA9S2N3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9S2N3" } ] } ] }, { "uniprot_ac": "A0AAA9S472", "gene_name": "MAPK8", "activity": [ { "ec_number": "2.7.11.24", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0AAA9S472", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9S472" } ] }, { "ec_number": "2.7.11.24", "activity": "", "evidence": [ { "id": "A0AAA9S472", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9S472" } ] } ] }, { "uniprot_ac": "A0AAA9S4Z4", "gene_name": "AKT1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0AAA9S4Z4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9S4Z4" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0AAA9S4Z4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9S4Z4" } ] } ] }, { "uniprot_ac": "A0AAA9S5X7", "gene_name": "AURKB", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0AAA9S5X7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9S5X7" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0AAA9S5X7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9S5X7" } ] } ] }, { "uniprot_ac": "A0AAA9S663", "gene_name": "PDPK1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0AAA9S663", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9S663" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0AAA9S663", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9S663" } ] } ] }, { "uniprot_ac": "A0AAA9S954", "gene_name": "CAMKK1", "activity": [ { "ec_number": "2.7.11.17", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0AAA9S954", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9S954" } ] }, { "ec_number": "2.7.11.17", "activity": "", "evidence": [ { "id": "A0AAA9S954", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9S954" } ] } ] }, { "uniprot_ac": "A0AAA9S9A9", "gene_name": "NEK11", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0AAA9S9A9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9S9A9" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0AAA9S9A9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9S9A9" } ] } ] }, { "uniprot_ac": "A0AAA9SG01", "gene_name": "ERN1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0AAA9SG01", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9SG01" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0AAA9SG01", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9SG01" } ] } ] }, { "uniprot_ac": "A0AAA9SGM8", "gene_name": "MKNK1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0AAA9SGM8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9SGM8" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0AAA9SGM8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9SGM8" } ] } ] }, { "uniprot_ac": "A0AAA9SH90", "gene_name": "DAPK2", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0AAA9SH90", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9SH90" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0AAA9SH90", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9SH90" } ] } ] }, { "uniprot_ac": "A0AAA9SIK7", "gene_name": "NEK10", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0AAA9SIK7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9SIK7" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0AAA9SIK7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9SIK7" } ] } ] }, { "uniprot_ac": "A0AAA9SJ92", "gene_name": "RPS6KA1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0AAA9SJ92", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9SJ92" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0AAA9SJ92", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9SJ92" } ] } ] }, { "uniprot_ac": "A0AAA9SJA3", "gene_name": "TTBK2", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0AAA9SJA3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9SJA3" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0AAA9SJA3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9SJA3" } ] } ] }, { "uniprot_ac": "A0AAA9SJQ0", "gene_name": "RPS6KA4", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0AAA9SJQ0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9SJQ0" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0AAA9SJQ0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9SJQ0" } ] } ] }, { "uniprot_ac": "A0AAA9SK35", "gene_name": "PRKG2", "activity": [ { "ec_number": "2.7.11.12", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0AAA9SK35", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9SK35" } ] }, { "ec_number": "2.7.11.12", "activity": "", "evidence": [ { "id": "A0AAA9SK35", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9SK35" } ] } ] }, { "uniprot_ac": "A0AAA9SKK8", "gene_name": "MAP3K4", "activity": [ { "ec_number": "2.7.11.25", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0AAA9SKK8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9SKK8" } ] }, { "ec_number": "2.7.11.25", "activity": "", "evidence": [ { "id": "A0AAA9SKK8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9SKK8" } ] } ] }, { "uniprot_ac": "A0AAA9SLY1", "gene_name": "NEK5", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0AAA9SLY1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9SLY1" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0AAA9SLY1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9SLY1" } ] } ] }, { "uniprot_ac": "A0AAA9SMH0", "gene_name": "DCLK3", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0AAA9SMH0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9SMH0" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0AAA9SMH0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9SMH0" } ] } ] }, { "uniprot_ac": "A0AAA9SMT9", "gene_name": "MAP3K12", "activity": [ { "ec_number": "2.7.11.25", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0AAA9SMT9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9SMT9" } ] }, { "ec_number": "2.7.11.25", "activity": "", "evidence": [ { "id": "A0AAA9SMT9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9SMT9" } ] } ] }, { "uniprot_ac": "A0AAA9SNP6", "gene_name": "MOS", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0AAA9SNP6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9SNP6" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0AAA9SNP6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9SNP6" } ] } ] }, { "uniprot_ac": "A0AAA9SU81", "gene_name": "PRKAA2", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0AAA9SU81", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9SU81" } ] }, { "ec_number": "2.7.11.31", "activity": "L-seryl-[acetyl-CoA carboxylase] + ATP = O-phospho-L-seryl-[acetyl-CoA carboxylase] + ADP + H(+).", "evidence": [ { "id": "A0AAA9SU81", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9SU81" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0AAA9SU81", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9SU81" } ] }, { "ec_number": "2.7.11.31", "activity": "", "evidence": [ { "id": "A0AAA9SU81", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9SU81" } ] } ] }, { "uniprot_ac": "A0AAA9SVM5", "gene_name": "MAP3K3", "activity": [ { "ec_number": "2.7.11.25", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0AAA9SVM5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9SVM5" } ] }, { "ec_number": "2.7.11.25", "activity": "", "evidence": [ { "id": "A0AAA9SVM5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9SVM5" } ] } ] }, { "uniprot_ac": "A0AAA9SWA1", "gene_name": "STK26", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0AAA9SWA1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9SWA1" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0AAA9SWA1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9SWA1" } ] } ] }, { "uniprot_ac": "A0AAA9SX77", "gene_name": "CDK14", "activity": [ { "ec_number": "2.7.11.22", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0AAA9SX77", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9SX77" } ] }, { "ec_number": "2.7.11.22", "activity": "", "evidence": [ { "id": "A0AAA9SX77", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9SX77" } ] } ] }, { "uniprot_ac": "A0AAA9SXE3", "gene_name": "MAP3K6", "activity": [ { "ec_number": "2.7.11.25", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0AAA9SXE3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9SXE3" } ] }, { "ec_number": "2.7.11.25", "activity": "", "evidence": [ { "id": "A0AAA9SXE3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9SXE3" } ] } ] }, { "uniprot_ac": "A0AAA9SYW5", "gene_name": "NEK3", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0AAA9SYW5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9SYW5" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0AAA9SYW5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9SYW5" } ] } ] }, { "uniprot_ac": "A0AAA9T042", "gene_name": "DYRK4", "activity": [ { "ec_number": "2.7.12.1", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0AAA9T042", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9T042" } ] }, { "ec_number": "2.7.12.1", "activity": "", "evidence": [ { "id": "A0AAA9T042", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9T042" } ] } ] }, { "uniprot_ac": "A0AAA9T2F0", "gene_name": "BRAF", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0AAA9T2F0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9T2F0" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0AAA9T2F0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9T2F0" } ] } ] }, { "uniprot_ac": "A0AAA9T3H7", "gene_name": "TNK1", "activity": [ { "ec_number": "2.7.10.2", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0AAA9T3H7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9T3H7" } ] }, { "ec_number": "2.7.10.2", "activity": "", "evidence": [ { "id": "A0AAA9T3H7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9T3H7" } ] } ] }, { "uniprot_ac": "A0AAA9T3K7", "gene_name": "WNK3", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0AAA9T3K7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9T3K7" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0AAA9T3K7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9T3K7" } ] } ] }, { "uniprot_ac": "A0AAA9T584", "gene_name": "CSNK1G3", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0AAA9T584", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9T584" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0AAA9T584", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9T584" } ] } ] }, { "uniprot_ac": "A0AAA9T593", "gene_name": "SRPK1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0AAA9T593", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9T593" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0AAA9T593", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9T593" } ] } ] }, { "uniprot_ac": "A0AAA9T5C9", "gene_name": "MAPK1", "activity": [ { "ec_number": "2.7.11.24", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0AAA9T5C9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9T5C9" } ] }, { "ec_number": "2.7.11.24", "activity": "", "evidence": [ { "id": "A0AAA9T5C9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9T5C9" } ] } ] }, { "uniprot_ac": "A0AAA9T7I8", "gene_name": "TSSK2", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0AAA9T7I8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9T7I8" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0AAA9T7I8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9T7I8" } ] } ] }, { "uniprot_ac": "A0AAA9T7L6", "gene_name": "RPS6KC1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0AAA9T7L6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9T7L6" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0AAA9T7L6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9T7L6" } ] } ] }, { "uniprot_ac": "A0AAA9T7Z7", "gene_name": "RPS6KA5", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0AAA9T7Z7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9T7Z7" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0AAA9T7Z7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9T7Z7" } ] } ] }, { "uniprot_ac": "A0AAA9T8T9", "gene_name": "MARK2", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0AAA9T8T9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9T8T9" } ] }, { "ec_number": "2.7.11.26", "activity": "L-seryl-[tau protein] + ATP = O-phospho-L-seryl-[tau protein] + ADP + H(+).", "evidence": [ { "id": "A0AAA9T8T9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9T8T9" } ] }, { "ec_number": "2.7.11.26", "activity": "", "evidence": [ { "id": "A0AAA9T8T9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9T8T9" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0AAA9T8T9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9T8T9" } ] } ] }, { "uniprot_ac": "A0AAA9T8Z3", "gene_name": "STK32C", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0AAA9T8Z3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9T8Z3" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0AAA9T8Z3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9T8Z3" } ] } ] }, { "uniprot_ac": "A0AAA9T940", "gene_name": "PLK2", "activity": [ { "ec_number": "2.7.11.21", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0AAA9T940", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9T940" } ] }, { "ec_number": "2.7.11.21", "activity": "", "evidence": [ { "id": "A0AAA9T940", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9T940" } ] } ] }, { "uniprot_ac": "A0AAA9TCI9", "gene_name": "MOK", "activity": [ { "ec_number": "2.7.11.22", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0AAA9TCI9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TCI9" } ] }, { "ec_number": "2.7.11.22", "activity": "", "evidence": [ { "id": "A0AAA9TCI9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TCI9" } ] } ] }, { "uniprot_ac": "A0AAA9TD48", "gene_name": "DYRK1B", "activity": [ { "ec_number": "2.7.12.1", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0AAA9TD48", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TD48" } ] }, { "ec_number": "2.7.12.1", "activity": "", "evidence": [ { "id": "A0AAA9TD48", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TD48" } ] } ] }, { "uniprot_ac": "A0AAA9TDL1", "gene_name": "SBK1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0AAA9TDL1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TDL1" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0AAA9TDL1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TDL1" } ] } ] }, { "uniprot_ac": "A0AAA9TJD5", "gene_name": "", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0AAA9TJD5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TJD5" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0AAA9TJD5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TJD5" } ] } ] }, { "uniprot_ac": "A0AAA9TLV0", "gene_name": "STK32B", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0AAA9TLV0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TLV0" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0AAA9TLV0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TLV0" } ] } ] }, { "uniprot_ac": "A0AAA9TMV7", "gene_name": "SMG1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0AAA9TMV7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TMV7" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0AAA9TMV7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TMV7" } ] } ] }, { "uniprot_ac": "A0AAA9TNE6", "gene_name": "TLK2", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0AAA9TNE6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TNE6" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0AAA9TNE6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TNE6" } ] } ] }, { "uniprot_ac": "A0AAA9TNL3", "gene_name": "SLK", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0AAA9TNL3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TNL3" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0AAA9TNL3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TNL3" } ] } ] }, { "uniprot_ac": "A0AAA9TP92", "gene_name": "CAMK1", "activity": [ { "ec_number": "2.7.11.17", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0AAA9TP92", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TP92" } ] }, { "ec_number": "2.7.11.17", "activity": "", "evidence": [ { "id": "A0AAA9TP92", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TP92" } ] } ] }, { "uniprot_ac": "A0AAA9TU12", "gene_name": "PRKCQ", "activity": [ { "ec_number": "2.7.11.13", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0AAA9TU12", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TU12" } ] }, { "ec_number": "2.7.11.13", "activity": "", "evidence": [ { "id": "A0AAA9TU12", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TU12" } ] } ] }, { "uniprot_ac": "A0AAA9TVT5", "gene_name": "CASK", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0AAA9TVT5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TVT5" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0AAA9TVT5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TVT5" } ] } ] }, { "uniprot_ac": "A0AAA9TWW0", "gene_name": "TBK1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0AAA9TWW0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TWW0" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0AAA9TWW0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TWW0" } ] } ] }, { "uniprot_ac": "A0AAA9U136", "gene_name": "PRKD2", "activity": [ { "ec_number": "2.7.11.13", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": 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"ec_number": "2.7.11.22", "activity": "", "evidence": [ { "id": "A0AAF6DLR2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAF6DLR2" } ] } ] }, { "uniprot_ac": "A0AAF6DMH7", "gene_name": "RIPK1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0AAF6DMH7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAF6DMH7" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0AAF6DMH7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAF6DMH7" } ] } ] }, { "uniprot_ac": "A0AAF6YHL8", "gene_name": "MAPK7", "activity": [ { "ec_number": "2.7.11.24", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0AAF6YHL8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAF6YHL8" } ] }, { "ec_number": "2.7.11.24", "activity": "", "evidence": [ { "id": "A0AAF6YHL8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAF6YHL8" } ] } ] }, { "uniprot_ac": "A0AAF6YMX3", "gene_name": "CDK9", "activity": [ { "ec_number": "2.7.11.22", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0AAF6YMX3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAF6YMX3" } ] }, { "ec_number": "2.7.11.23", "activity": "[DNA-directed RNA polymerase] + ATP = phospho-[DNA-directed RNA polymerase] + ADP + H(+).", "evidence": [ { "id": "A0AAF6YMX3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAF6YMX3" } ] }, { "ec_number": "2.7.11.22", "activity": "", "evidence": [ { "id": "A0AAF6YMX3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAF6YMX3" } ] }, { "ec_number": "2.7.11.23", "activity": "", "evidence": [ { "id": "A0AAF6YMX3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAF6YMX3" } ] } ] }, { "uniprot_ac": "A0AAF6Z257", "gene_name": "IRAK1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0AAF6Z257", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAF6Z257" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0AAF6Z257", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAF6Z257" } ] } ] }, { "uniprot_ac": "A0ABI0NJ75", "gene_name": "PAK6", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0ABI0NJ75", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NJ75" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0ABI0NJ75", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NJ75" } ] } ] }, { "uniprot_ac": "A0ABI0NM98", "gene_name": "KALRN", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0ABI0NM98", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NM98" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0ABI0NM98", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NM98" } ] } ] }, { "uniprot_ac": "A0ABI0NMT8", "gene_name": "PIK3CG", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0ABI0NMT8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NMT8" } ] }, { "ec_number": "2.7.1.153", "activity": "a 1,2-diacyl-sn-glycero-3-phospho-(1D-myo-inositol-4,5-bisphosphate) + ATP = a 1,2-diacyl-sn-glycero-3-phospho-(1D-myo-inositol-3,4,5-trisphosphate) + ADP + H(+).", "evidence": [ { "id": "A0ABI0NMT8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NMT8" } ] }, { "ec_number": "2.7.1.137", "activity": "a 1,2-diacyl-sn-glycero-3-phospho-(1D-myo-inositol) + ATP = a 1,2-diacyl-sn-glycero-3-phospho-(1D-myo-inositol-3-phosphate) + ADP + H(+).", "evidence": [ { "id": "A0ABI0NMT8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NMT8" } ] }, { "ec_number": "2.7.1.154", "activity": "a 1,2-diacyl-sn-glycero-3-phospho-(1D-myo-inositol 4-phosphate) + ATP = a 1,2-diacyl-sn-glycero-3-phospho-(1D-myo-inositol-3,4-bisphosphate) + ADP + H(+).", "evidence": [ { "id": "A0ABI0NMT8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NMT8" } ] }, { "ec_number": "2.7.1.153", "activity": "", "evidence": [ { "id": "A0ABI0NMT8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NMT8" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0ABI0NMT8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NMT8" } ] }, { "ec_number": "2.7.1.137", "activity": "", "evidence": [ { "id": "A0ABI0NMT8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NMT8" } ] }, { "ec_number": "2.7.1.154", "activity": "", "evidence": [ { "id": "A0ABI0NMT8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NMT8" } ] } ] }, { "uniprot_ac": "A0ABI0NQQ4", "gene_name": "PRKAA1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0ABI0NQQ4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NQQ4" } ] }, { "ec_number": "2.7.11.26", "activity": "L-seryl-[tau protein] + ATP = O-phospho-L-seryl-[tau protein] + ADP + H(+).", "evidence": [ { "id": "A0ABI0NQQ4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NQQ4" } ] }, { "ec_number": "2.7.11.31", "activity": "L-seryl-[acetyl-CoA carboxylase] + ATP = O-phospho-L-seryl-[acetyl-CoA carboxylase] + ADP + H(+).", "evidence": [ { "id": "A0ABI0NQQ4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NQQ4" } ] }, { "ec_number": "2.7.11.26", "activity": "", "evidence": [ { "id": "A0ABI0NQQ4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NQQ4" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0ABI0NQQ4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NQQ4" } ] }, { "ec_number": "2.7.11.31", "activity": "", "evidence": [ { "id": "A0ABI0NQQ4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NQQ4" } ] } ] }, { "uniprot_ac": "A0ABI0NRQ5", "gene_name": "LOC101905399", "activity": [ { "ec_number": "2.7.12.2", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0ABI0NRQ5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NRQ5" } ] }, { "ec_number": "2.7.12.2", "activity": "", "evidence": [ { "id": "A0ABI0NRQ5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NRQ5" } ] } ] }, { "uniprot_ac": "A0ABI0NS30", "gene_name": "PRKCA", "activity": [ { "ec_number": "2.7.11.13", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0ABI0NS30", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NS30" } ] }, { "ec_number": "2.7.11.13", "activity": "", "evidence": [ { "id": "A0ABI0NS30", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NS30" } ] } ] }, { "uniprot_ac": "A0ABI0NV47", "gene_name": "DCLK1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0ABI0NV47", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NV47" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0ABI0NV47", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NV47" } ] } ] }, { "uniprot_ac": "A0ABI0P0X3", "gene_name": "", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0ABI0P0X3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0ABI0P0X3" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0ABI0P0X3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0ABI0P0X3" } ] } ] }, { "uniprot_ac": "A0ABI0P2C0", "gene_name": "TSSK5", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0ABI0P2C0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0ABI0P2C0" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0ABI0P2C0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0ABI0P2C0" } ] } ] }, { "uniprot_ac": "A0ABI0P3N8", "gene_name": "", "activity": [ { "ec_number": "2.7.11.22", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0ABI0P3N8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0ABI0P3N8" } ] }, { "ec_number": "2.7.11.22", "activity": "", "evidence": [ { "id": "A0ABI0P3N8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0ABI0P3N8" } ] } ] }, { "uniprot_ac": "A0ABI0P3P6", "gene_name": "MAST4", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0ABI0P3P6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0ABI0P3P6" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0ABI0P3P6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0ABI0P3P6" } ] } ] }, { "uniprot_ac": "A0ABI0P443", "gene_name": "SGK2", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0ABI0P443", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0ABI0P443" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0ABI0P443", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0ABI0P443" } ] } ] }, { "uniprot_ac": "A1A4I4", "gene_name": "PKN1", "activity": [ { "ec_number": "2.7.11.13", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A1A4I4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A1A4I4" } ] }, { "ec_number": "2.7.11.13", "activity": "", "evidence": [ { "id": "A1A4I4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A1A4I4" } ] } ] }, { "uniprot_ac": "A2VDU3", "gene_name": "MAP3K7", "activity": [ { "ec_number": "2.7.11.25", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A2VDU3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A2VDU3" } ] }, { "ec_number": "2.7.11.25", "activity": "", "evidence": [ { "id": "A2VDU3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A2VDU3" } ] } ] }, { "uniprot_ac": "A2VDV2", "gene_name": "STK38", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A2VDV2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A2VDV2" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A2VDV2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A2VDV2" } ] } ] }, { "uniprot_ac": "A2VDZ4", "gene_name": "PLK4", "activity": [ { "ec_number": "2.7.11.21", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A2VDZ4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A2VDZ4" } ] }, { "ec_number": "2.7.11.21", "activity": "", "evidence": [ { "id": "A2VDZ4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A2VDZ4" } ] } ] }, { "uniprot_ac": "A5D791", "gene_name": "EIF2AK3", "activity": [ { "ec_number": "2.7.10.2", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "A5D791", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A5D791" } ] }, { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A5D791", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A5D791" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A5D791", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A5D791" } ] } ] }, { "uniprot_ac": "A5PKJ4", "gene_name": "MAPK7", "activity": [ { "ec_number": "2.7.11.24", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A5PKJ4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A5PKJ4" } ] }, { "ec_number": "2.7.11.24", "activity": "", "evidence": [ { "id": "A5PKJ4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A5PKJ4" } ] } ] }, { "uniprot_ac": "A7E3S4", "gene_name": "RAF1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A7E3S4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A7E3S4" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A7E3S4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A7E3S4" } ] } ] }, { "uniprot_ac": "A7E3X2", "gene_name": "CSNK1G1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A7E3X2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A7E3X2" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A7E3X2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A7E3X2" } ] } ] }, { "uniprot_ac": "A7MB74", "gene_name": "SGK1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A7MB74", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A7MB74" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A7MB74", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A7MB74" } ] } ] }, { "uniprot_ac": "A7MBB4", "gene_name": "MAP3K13", "activity": [ { "ec_number": "2.7.11.25", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A7MBB4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A7MBB4" } ] }, { "ec_number": "2.7.11.25", "activity": "", "evidence": [ { "id": "A7MBB4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A7MBB4" } ] } ] }, { "uniprot_ac": "E1B754", "gene_name": "MAST2", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "E1B754", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1B754" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "E1B754", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1B754" } ] } ] }, { "uniprot_ac": "E1B793", "gene_name": "STK36", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "E1B793", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1B793" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "E1B793", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1B793" } ] } ] }, { "uniprot_ac": "E1B7H4", "gene_name": "MAP3K10", "activity": [ { "ec_number": "2.7.11.25", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "E1B7H4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1B7H4" } ] }, { "ec_number": "2.7.11.25", "activity": "", "evidence": [ { "id": "E1B7H4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1B7H4" } ] } ] }, { "uniprot_ac": "E1B7L9", "gene_name": "PRKD3", "activity": [ { "ec_number": "2.7.11.13", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "E1B7L9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1B7L9" } ] }, { "ec_number": "2.7.11.13", "activity": "", "evidence": [ { "id": "E1B7L9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1B7L9" } ] } ] }, { "uniprot_ac": "E1B827", "gene_name": "NEK8", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "E1B827", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1B827" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "E1B827", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1B827" } ] } ] }, { "uniprot_ac": "E1B887", "gene_name": "RIOK1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "E1B887", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1B887" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "E1B887", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1B887" } ] } ] }, { "uniprot_ac": "E1B8J7", "gene_name": "ERN2", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "E1B8J7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1B8J7" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "E1B8J7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1B8J7" } ] } ] }, { "uniprot_ac": "E1B8P9", "gene_name": "MAPK3", "activity": [ { "ec_number": "2.7.11.24", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "E1B8P9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1B8P9" } ] }, { "ec_number": "2.7.11.24", "activity": "", "evidence": [ { "id": "E1B8P9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1B8P9" } ] } ] }, { "uniprot_ac": "E1B902", "gene_name": "MAP4K2", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "E1B902", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1B902" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "E1B902", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1B902" } ] } ] }, { "uniprot_ac": "E1B9B6", "gene_name": "NUAK1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "E1B9B6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1B9B6" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "E1B9B6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1B9B6" } ] } ] }, { "uniprot_ac": "E1B9F9", "gene_name": "LATS2", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "E1B9F9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1B9F9" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "E1B9F9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1B9F9" } ] } ] }, { "uniprot_ac": "E1B9Q2", "gene_name": "CLK2", "activity": [ { "ec_number": "2.7.12.1", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "E1B9Q2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1B9Q2" } ] }, { "ec_number": "2.7.12.1", "activity": "", "evidence": [ { "id": "E1B9Q2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1B9Q2" } ] } ] }, { "uniprot_ac": "E1BAL6", "gene_name": "EIF2AK4", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "E1BAL6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BAL6" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "E1BAL6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BAL6" } ] } ] }, { "uniprot_ac": "E1BB49", "gene_name": "HIPK4", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "E1BB49", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BB49" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "E1BB49", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BB49" } ] } ] }, { "uniprot_ac": "E1BB50", "gene_name": "CDK12", "activity": [ { "ec_number": "2.7.11.22", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "E1BB50", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BB50" } ] }, { "ec_number": "2.7.11.23", "activity": "[DNA-directed RNA polymerase] + ATP = phospho-[DNA-directed RNA polymerase] + ADP + H(+).", "evidence": [ { "id": "E1BB50", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BB50" } ] }, { "ec_number": "2.7.11.23", "activity": "", "evidence": [ { "id": "E1BB50", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BB50" } ] }, { "ec_number": "2.7.11.22", "activity": "", "evidence": [ { "id": "E1BB50", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BB50" } ] } ] }, { "uniprot_ac": "E1BB52", "gene_name": "CDK13", "activity": [ { "ec_number": "2.7.11.22", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "E1BB52", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BB52" } ] }, { "ec_number": "2.7.11.23", "activity": "[DNA-directed RNA polymerase] + ATP = phospho-[DNA-directed RNA polymerase] + ADP + H(+).", "evidence": [ { "id": "E1BB52", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BB52" } ] }, { "ec_number": "2.7.11.23", "activity": "", "evidence": [ { "id": "E1BB52", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BB52" } ] }, { "ec_number": "2.7.11.22", "activity": "", "evidence": [ { "id": "E1BB52", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BB52" } ] } ] }, { "uniprot_ac": "E1BBM3", "gene_name": "NEK1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "E1BBM3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BBM3" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "E1BBM3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BBM3" } ] } ] }, { "uniprot_ac": "E1BC36", "gene_name": "CDK6", "activity": [ { "ec_number": "2.7.11.22", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "E1BC36", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BC36" } ] }, { "ec_number": "2.7.11.22", "activity": "", "evidence": [ { "id": "E1BC36", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BC36" } ] } ] }, { "uniprot_ac": "E1BC64", "gene_name": "LIMK1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "E1BC64", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BC64" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "E1BC64", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BC64" } ] } ] }, { "uniprot_ac": "E1BC69", "gene_name": "HIPK3", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "E1BC69", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BC69" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "E1BC69", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BC69" } ] } ] }, { "uniprot_ac": "E1BCC3", "gene_name": "UHMK1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "E1BCC3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BCC3" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "E1BCC3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BCC3" } ] } ] }, { "uniprot_ac": "E1BCH5", "gene_name": "LATS1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "E1BCH5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BCH5" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "E1BCH5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BCH5" } ] } ] }, { "uniprot_ac": "E1BCU9", "gene_name": "STK11", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "E1BCU9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BCU9" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "E1BCU9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BCU9" } ] } ] }, { "uniprot_ac": "E1BDG4", "gene_name": "MAK", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "E1BDG4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BDG4" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "E1BDG4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BDG4" } ] } ] }, { "uniprot_ac": "E1BEI6", "gene_name": "ATM", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "E1BEI6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BEI6" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "E1BEI6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BEI6" } ] } ] }, { "uniprot_ac": "E1BEW4", "gene_name": "LOC613515", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "E1BEW4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BEW4" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "E1BEW4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BEW4" } ] } ] }, { "uniprot_ac": "E1BFR5", "gene_name": "MASTL", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "E1BFR5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BFR5" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "E1BFR5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BFR5" } ] } ] }, { "uniprot_ac": "E1BFV2", "gene_name": "MAP3K21", "activity": [ { "ec_number": "2.7.11.25", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "E1BFV2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BFV2" } ] }, { "ec_number": "2.7.11.25", "activity": "", "evidence": [ { "id": "E1BFV2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BFV2" } ] } ] }, { "uniprot_ac": "E1BG90", "gene_name": "DYRK2", "activity": [ { "ec_number": "2.7.12.1", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "E1BG90", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BG90" } ] }, { "ec_number": "2.7.12.1", "activity": "", "evidence": [ { "id": "E1BG90", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BG90" } ] } ] }, { "uniprot_ac": "E1BGV8", "gene_name": "MAP3K19", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "E1BGV8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BGV8" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "E1BGV8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BGV8" } ] } ] }, { "uniprot_ac": "E1BH31", "gene_name": "MAP4K1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "E1BH31", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BH31" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "E1BH31", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BH31" } ] } ] }, { "uniprot_ac": "E1BHE1", "gene_name": "TAOK3", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "E1BHE1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BHE1" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "E1BHE1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BHE1" } ] } ] }, { "uniprot_ac": "E1BI01", "gene_name": "MAP2K5", "activity": [ { "ec_number": "2.7.12.2", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "E1BI01", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BI01" } ] }, { "ec_number": "2.7.12.2", "activity": "", "evidence": [ { "id": "E1BI01", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BI01" } ] } ] }, { "uniprot_ac": "E1BI47", "gene_name": "PLK5", "activity": [ { "ec_number": "2.7.11.21", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "E1BI47", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BI47" } ] }, { "ec_number": "2.7.11.21", "activity": "", "evidence": [ { "id": "E1BI47", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BI47" } ] } ] }, { "uniprot_ac": "E1BJ19", "gene_name": "TAOK1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "E1BJ19", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BJ19" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "E1BJ19", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BJ19" } ] } ] }, { "uniprot_ac": "E1BJH5", "gene_name": "MAP4K3", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "E1BJH5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BJH5" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "E1BJH5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BJH5" } ] } ] }, { "uniprot_ac": "E1BJM5", "gene_name": "MTERF4", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "E1BJM5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BJM5" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "E1BJM5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BJM5" } ] } ] }, { "uniprot_ac": "E1BK33", "gene_name": "MAST1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "E1BK33", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BK33" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "E1BK33", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BK33" } ] } ] }, { "uniprot_ac": "E1BK52", "gene_name": "STK10", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "E1BK52", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BK52" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "E1BK52", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BK52" } ] } ] }, { "uniprot_ac": "E1BKX9", "gene_name": "CDKL5", "activity": [ { "ec_number": "2.7.11.22", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "E1BKX9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BKX9" } ] }, { "ec_number": "2.7.11.22", "activity": "", "evidence": [ { "id": "E1BKX9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BKX9" } ] } ] }, { "uniprot_ac": "E1BL08", "gene_name": "MAP3K14", "activity": [ { "ec_number": "2.7.11.25", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "E1BL08", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BL08" } ] }, { "ec_number": "2.7.11.25", "activity": "", "evidence": [ { "id": "E1BL08", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BL08" } ] } ] }, { "uniprot_ac": "E1BLQ5", "gene_name": "RPS6KB2", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "E1BLQ5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BLQ5" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "E1BLQ5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BLQ5" } ] } ] }, { "uniprot_ac": "E1BM19", "gene_name": "CDKL3", "activity": [ { "ec_number": "2.7.11.22", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "E1BM19", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BM19" } ] }, { "ec_number": "2.7.11.22", "activity": "", "evidence": [ { "id": "E1BM19", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BM19" } ] } ] }, { "uniprot_ac": "E1BMN8", "gene_name": "NLK", "activity": [ { "ec_number": "2.7.11.24", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "E1BMN8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BMN8" } ] }, { "ec_number": "2.7.11.24", "activity": "", "evidence": [ { "id": "E1BMN8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BMN8" } ] } ] }, { "uniprot_ac": "E1BN63", "gene_name": "WNK1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "E1BN63", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BN63" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "E1BN63", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BN63" } ] } ] }, { "uniprot_ac": "E1BN72", "gene_name": "NIM1K", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "E1BN72", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BN72" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "E1BN72", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BN72" } ] } ] }, { "uniprot_ac": "E1BNH0", "gene_name": "WNK2", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "E1BNH0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BNH0" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "E1BNH0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BNH0" } ] } ] }, { "uniprot_ac": "E1BNS8", "gene_name": "SIK1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "E1BNS8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BNS8" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "E1BNS8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BNS8" } ] } ] }, { "uniprot_ac": "E1BP01", "gene_name": "MYO3A", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "E1BP01", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BP01" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "E1BP01", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BP01" } ] } ] }, { "uniprot_ac": "E1BP72", "gene_name": "CDC42BPB", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "E1BP72", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BP72" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "E1BP72", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BP72" } ] } ] }, { "uniprot_ac": "E1BPB5", "gene_name": "TESK1", "activity": [ { "ec_number": "2.7.12.1", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "E1BPB5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BPB5" } ] }, { "ec_number": "2.7.12.1", "activity": "", "evidence": [ { "id": "E1BPB5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BPB5" } ] } ] }, { "uniprot_ac": "E1BPP1", "gene_name": "TTK", "activity": [ { "ec_number": "2.7.12.1", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "E1BPP1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BPP1" } ] }, { "ec_number": "2.7.12.1", "activity": "", "evidence": [ { "id": "E1BPP1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BPP1" } ] } ] }, { "uniprot_ac": "E1BPU0", "gene_name": "LRRK2", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "E1BPU0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BPU0" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "E1BPU0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BPU0" } ] } ] }, { "uniprot_ac": "E1BQ34", "gene_name": "HIPK1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "E1BQ34", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BQ34" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "E1BQ34", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BQ34" } ] } ] }, { "uniprot_ac": "F1MAZ8", "gene_name": "MARK3", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "F1MAZ8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MAZ8" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "F1MAZ8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MAZ8" } ] } ] }, { "uniprot_ac": "F1MBN7", "gene_name": "RIOK2", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "F1MBN7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MBN7" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "F1MBN7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MBN7" } ] } ] }, { "uniprot_ac": "F1MC27", "gene_name": "LMTK3", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "F1MC27", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MC27" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "F1MC27", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MC27" } ] } ] }, { "uniprot_ac": "F1MC61", "gene_name": "MAP3K11", "activity": [ { "ec_number": "2.7.11.25", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "F1MC61", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MC61" } ] }, { "ec_number": "2.7.11.25", "activity": "", "evidence": [ { "id": "F1MC61", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MC61" } ] } ] }, { "uniprot_ac": "F1MDC9", "gene_name": "PRKCE", "activity": [ { "ec_number": "2.7.11.13", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "F1MDC9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MDC9" } ] }, { "ec_number": "2.7.11.13", "activity": "", "evidence": [ { "id": "F1MDC9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MDC9" } ] } ] }, { "uniprot_ac": "F1MDS3", "gene_name": "PCK2", "activity": [ { "ec_number": "4.1.1.32", "activity": "ITP + oxaloacetate = IDP + phosphoenolpyruvate + CO2.", "evidence": [ { "id": "F1MDS3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MDS3" } ] }, { "ec_number": "4.1.1.32", "activity": "", "evidence": [ { "id": "F1MDS3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MDS3" } ] } ] }, { "uniprot_ac": "F1MF36", "gene_name": "KSR2", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "F1MF36", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MF36" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "F1MF36", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MF36" } ] } ] }, { "uniprot_ac": "F1MF50", "gene_name": "ROCK1", "activity": [ { "ec_number": "2.7.11.39", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "F1MF50", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MF50" } ] }, { "ec_number": "2.7.11.39", "activity": "", "evidence": [ { "id": "F1MF50", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MF50" } ] } ] }, { "uniprot_ac": "F1MFK1", "gene_name": "PKN2", "activity": [ { "ec_number": "2.7.11.13", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "F1MFK1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MFK1" } ] }, { "ec_number": "2.7.11.13", "activity": "", "evidence": [ { "id": "F1MFK1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MFK1" } ] } ] }, { "uniprot_ac": "F1MG29", "gene_name": "TSSK3", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "F1MG29", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MG29" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "F1MG29", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MG29" } ] } ] }, { "uniprot_ac": "F1MG35", "gene_name": "CIITA", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "F1MG35", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MG35" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "F1MG35", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MG35" } ] } ] }, { "uniprot_ac": "F1MG77", "gene_name": "HASPIN", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "F1MG77", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MG77" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "F1MG77", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MG77" } ] } ] }, { "uniprot_ac": "F1MGX2", "gene_name": "MAP3K13", "activity": [ { "ec_number": "2.7.11.25", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "F1MGX2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MGX2" } ] }, { "ec_number": "2.7.11.25", "activity": "", "evidence": [ { "id": "F1MGX2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MGX2" } ] } ] }, { "uniprot_ac": "F1MH23", "gene_name": "MAPKAPK5", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "F1MH23", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MH23" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "F1MH23", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MH23" } ] } ] }, { "uniprot_ac": "F1MH24", "gene_name": "AAK1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "F1MH24", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MH24" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "F1MH24", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MH24" } ] } ] }, { "uniprot_ac": "F1MH45", "gene_name": "CDC42BPA", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "F1MH45", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MH45" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "F1MH45", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MH45" } ] } ] }, { "uniprot_ac": "F1MI60", "gene_name": "MAP4K4", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "F1MI60", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MI60" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "F1MI60", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MI60" } ] } ] }, { "uniprot_ac": "F1MIB2", "gene_name": "GAK", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "F1MIB2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MIB2" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "F1MIB2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MIB2" } ] } ] }, { "uniprot_ac": "F1MJ55", "gene_name": "CSNK2A2", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "F1MJ55", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MJ55" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "F1MJ55", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MJ55" } ] } ] }, { "uniprot_ac": "F1MKK7", "gene_name": "PKMYT1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "F1MKK7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MKK7" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "F1MKK7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MKK7" } ] } ] }, { "uniprot_ac": "F1MKW8", "gene_name": "SIK2", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "F1MKW8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MKW8" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "F1MKW8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MKW8" } ] } ] }, { "uniprot_ac": "F1MKY9", "gene_name": "ALPK2", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "F1MKY9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MKY9" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "F1MKY9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MKY9" } ] } ] }, { "uniprot_ac": "F1MLY7", "gene_name": "ATR", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "F1MLY7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MLY7" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "F1MLY7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MLY7" } ] } ] }, { "uniprot_ac": "F1MM88", "gene_name": "NEK9", "activity": [ { "ec_number": "2.7.11.38", "activity": "L-threonyl-[protein] + ATP = O-phospho-L-threonyl-[protein] + ADP + H(+).", "evidence": [ { "id": "F1MM88", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MM88" } ] }, { "ec_number": "2.7.11.38", "activity": "", "evidence": [ { "id": "F1MM88", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MM88" } ] } ] }, { "uniprot_ac": "F1MN35", "gene_name": "PDIK1L", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "F1MN35", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MN35" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "F1MN35", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MN35" } ] } ] }, { "uniprot_ac": "F1MNP4", "gene_name": "RPS6KB1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "F1MNP4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MNP4" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "F1MNP4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MNP4" } ] } ] }, { "uniprot_ac": "F1MPF0", "gene_name": "TRPM7", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "F1MPF0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MPF0" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "F1MPF0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MPF0" } ] } ] }, { "uniprot_ac": "F1MPI8", "gene_name": "CDK8", "activity": [ { "ec_number": "2.7.11.22", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "F1MPI8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MPI8" } ] }, { "ec_number": "2.7.11.23", "activity": "[DNA-directed RNA polymerase] + ATP = phospho-[DNA-directed RNA polymerase] + ADP + H(+).", "evidence": [ { "id": "F1MPI8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MPI8" } ] }, { "ec_number": "2.7.11.22", "activity": "", "evidence": [ { "id": "F1MPI8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MPI8" } ] }, { "ec_number": "2.7.11.23", "activity": "", "evidence": [ { "id": "F1MPI8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MPI8" } ] } ] }, { "uniprot_ac": "F1MQ96", "gene_name": "PRKCI", "activity": [ { "ec_number": "2.7.11.13", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "F1MQ96", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MQ96" } ] }, { "ec_number": "2.7.11.13", "activity": "", "evidence": [ { "id": "F1MQ96", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MQ96" } ] } ] }, { "uniprot_ac": "F1MSI1", "gene_name": "STK17B", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "F1MSI1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MSI1" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "F1MSI1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MSI1" } ] } ] }, { "uniprot_ac": "F1MSV4", "gene_name": "SGK3", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "F1MSV4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MSV4" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "F1MSV4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MSV4" } ] } ] }, { "uniprot_ac": "F1MSX4", "gene_name": "MAP3K2", "activity": [ { "ec_number": "2.7.11.25", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "F1MSX4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MSX4" } ] }, { "ec_number": "2.7.11.25", "activity": "", "evidence": [ { "id": "F1MSX4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MSX4" } ] } ] }, { "uniprot_ac": "F1MU35", "gene_name": "PRKCG", "activity": [ { "ec_number": "2.7.11.13", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "F1MU35", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MU35" } ] }, { "ec_number": "2.7.11.13", "activity": "", "evidence": [ { "id": "F1MU35", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MU35" } ] } ] }, { "uniprot_ac": "F1MUU2", "gene_name": "STK35", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "F1MUU2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MUU2" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "F1MUU2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MUU2" } ] } ] }, { "uniprot_ac": "F1MVR0", "gene_name": "CDK19", "activity": [ { "ec_number": "2.7.11.22", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "F1MVR0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MVR0" } ] }, { "ec_number": "2.7.11.22", "activity": "", "evidence": [ { "id": "F1MVR0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MVR0" } ] } ] }, { "uniprot_ac": "F1MVV5", "gene_name": "MAPK4", "activity": [ { "ec_number": "2.7.11.24", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "F1MVV5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MVV5" } ] }, { "ec_number": "2.7.11.24", "activity": "", "evidence": [ { "id": "F1MVV5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MVV5" } ] } ] }, { "uniprot_ac": "F1MWN0", "gene_name": "EIF2AK1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "F1MWN0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MWN0" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "F1MWN0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MWN0" } ] } ] }, { "uniprot_ac": "F1MWP1", "gene_name": "BUB1B", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "F1MWP1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MWP1" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "F1MWP1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MWP1" } ] } ] }, { "uniprot_ac": "F1MXH6", "gene_name": "MAP3K5", "activity": [ { "ec_number": "2.7.11.25", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "F1MXH6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MXH6" } ] }, { "ec_number": "2.7.11.25", "activity": "", "evidence": [ { "id": "F1MXH6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MXH6" } ] } ] }, { "uniprot_ac": "F1MY55", "gene_name": "PAK5", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "F1MY55", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MY55" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "F1MY55", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MY55" } ] } ] }, { "uniprot_ac": "F1MY82", "gene_name": "PRKCH", "activity": [ { "ec_number": "2.7.11.13", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "F1MY82", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MY82" } ] }, { "ec_number": "2.7.11.13", "activity": "", "evidence": [ { "id": "F1MY82", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MY82" } ] } ] }, { "uniprot_ac": "F1MY86", "gene_name": "AURKC", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "F1MY86", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MY86" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "F1MY86", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MY86" } ] } ] }, { "uniprot_ac": "F1MYG2", "gene_name": "TLK1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "F1MYG2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MYG2" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "F1MYG2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MYG2" } ] } ] }, { "uniprot_ac": "F1MYM3", "gene_name": "PIK3CB", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "F1MYM3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MYM3" } ] }, { "ec_number": "2.7.1.153", "activity": "a 1,2-diacyl-sn-glycero-3-phospho-(1D-myo-inositol-4,5-bisphosphate) + ATP = a 1,2-diacyl-sn-glycero-3-phospho-(1D-myo-inositol-3,4,5-trisphosphate) + ADP + H(+).", "evidence": [ { "id": "F1MYM3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MYM3" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "F1MYM3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MYM3" } ] }, { "ec_number": "2.7.1.153", "activity": "", "evidence": [ { "id": "F1MYM3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MYM3" } ] } ] }, { "uniprot_ac": "F1MYV9", "gene_name": "OXSR1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "F1MYV9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MYV9" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "F1MYV9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MYV9" } ] } ] }, { "uniprot_ac": "F1N063", "gene_name": "CAMK1D", "activity": [ { "ec_number": "2.7.11.17", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "F1N063", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1N063" } ] }, { "ec_number": "2.7.11.17", "activity": "", "evidence": [ { "id": "F1N063", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1N063" } ] } ] }, { "uniprot_ac": "F1N2S7", "gene_name": "TSSK6", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "F1N2S7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1N2S7" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "F1N2S7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1N2S7" } ] } ] }, { "uniprot_ac": "F1N332", "gene_name": "ULK3", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "F1N332", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1N332" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "F1N332", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1N332" } ] } ] }, { "uniprot_ac": "F1N3W6", "gene_name": "MAP3K15", "activity": [ { "ec_number": "2.7.11.25", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "F1N3W6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1N3W6" } ] }, { "ec_number": "2.7.11.25", "activity": "", "evidence": [ { "id": "F1N3W6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1N3W6" } ] } ] }, { "uniprot_ac": "F1N5K1", "gene_name": "CDK11B", "activity": [ { "ec_number": "2.7.11.22", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "F1N5K1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1N5K1" } ] }, { "ec_number": "2.7.11.23", "activity": "[DNA-directed RNA polymerase] + ATP = phospho-[DNA-directed RNA polymerase] + ADP + H(+).", "evidence": [ { "id": "F1N5K1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1N5K1" } ] }, { "ec_number": "2.7.11.23", "activity": "", "evidence": [ { "id": "F1N5K1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1N5K1" } ] }, { "ec_number": "2.7.11.22", "activity": "", "evidence": [ { "id": "F1N5K1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1N5K1" } ] } ] }, { "uniprot_ac": "F1N5U0", "gene_name": "ALPK3", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "F1N5U0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1N5U0" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "F1N5U0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1N5U0" } ] } ] }, { "uniprot_ac": "F1N664", "gene_name": "MAP2K7", "activity": [ { "ec_number": "2.7.12.2", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "F1N664", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1N664" } ] }, { "ec_number": "2.7.12.2", "activity": "", "evidence": [ { "id": "F1N664", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1N664" } ] } ] }, { "uniprot_ac": "F1N6C1", "gene_name": "LRRK1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "F1N6C1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1N6C1" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "F1N6C1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1N6C1" } ] } ] }, { "uniprot_ac": "F6PN06", "gene_name": "TNK2", "activity": [ { "ec_number": "2.7.10.2", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "F6PN06", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F6PN06" } ] }, { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "F6PN06", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F6PN06" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "F6PN06", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F6PN06" } ] }, { "ec_number": "2.7.10.2", "activity": "", "evidence": [ { "id": "F6PN06", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F6PN06" } ] } ] }, { "uniprot_ac": "F6Q5B6", "gene_name": "EIF2AK2", "activity": [ { "ec_number": "2.7.10.2", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "F6Q5B6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F6Q5B6" } ] }, { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "F6Q5B6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F6Q5B6" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "F6Q5B6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F6Q5B6" } ] }, { "ec_number": "2.7.10.2", "activity": "", "evidence": [ { "id": "F6Q5B6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F6Q5B6" } ] } ] }, { "uniprot_ac": "F6Q5Z6", "gene_name": "BUB1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "F6Q5Z6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F6Q5Z6" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "F6Q5Z6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F6Q5Z6" } ] } ] }, { "uniprot_ac": "F6Q6K1", "gene_name": "CHEK1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "F6Q6K1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F6Q6K1" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "F6Q6K1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F6Q6K1" } ] } ] }, { "uniprot_ac": "F6Q9U9", "gene_name": "PNCK", "activity": [ { "ec_number": "2.7.11.17", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "F6Q9U9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F6Q9U9" } ] }, { "ec_number": "2.7.11.17", "activity": "", "evidence": [ { "id": "F6Q9U9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F6Q9U9" } ] } ] }, { "uniprot_ac": "F6QTX4", "gene_name": "RIPK3", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "F6QTX4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F6QTX4" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "F6QTX4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F6QTX4" } ] } ] }, { "uniprot_ac": "F6QVY2", "gene_name": "CDK20", "activity": [ { "ec_number": "2.7.11.22", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "F6QVY2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F6QVY2" } ] }, { "ec_number": "2.7.11.22", "activity": "", "evidence": [ { "id": "F6QVY2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F6QVY2" } ] } ] }, { "uniprot_ac": "F6QY93", "gene_name": "CDK3", "activity": [ { "ec_number": "2.7.11.22", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "F6QY93", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F6QY93" } ] }, { "ec_number": "2.7.11.22", "activity": "", "evidence": [ { "id": "F6QY93", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F6QY93" } ] } ] }, { "uniprot_ac": "F6RD87", "gene_name": "SRPK3", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "F6RD87", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F6RD87" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "F6RD87", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F6RD87" } ] } ] }, { "uniprot_ac": "F6RG88", "gene_name": "NEK4", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "F6RG88", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F6RG88" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "F6RG88", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F6RG88" } ] } ] }, { "uniprot_ac": "F6RLA2", "gene_name": "TSSK4", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "F6RLA2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F6RLA2" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "F6RLA2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F6RLA2" } ] } ] }, { "uniprot_ac": "F6RP02", "gene_name": "PIM2", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "F6RP02", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F6RP02" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "F6RP02", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F6RP02" } ] } ] }, { "uniprot_ac": "F6RPH3", "gene_name": "MAPK13", "activity": [ { "ec_number": "2.7.11.24", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "F6RPH3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F6RPH3" } ] }, { "ec_number": "2.7.11.24", "activity": "", "evidence": [ { "id": "F6RPH3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F6RPH3" } ] } ] }, { "uniprot_ac": "G3MX00", "gene_name": "", "activity": [ { "ec_number": "2.7.11.22", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "G3MX00", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3MX00" } ] }, { "ec_number": "2.7.11.22", "activity": "", "evidence": [ { "id": "G3MX00", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3MX00" } ] } ] }, { "uniprot_ac": "G3N022", "gene_name": "SPEG", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "G3N022", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3N022" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "G3N022", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3N022" } ] } ] }, { "uniprot_ac": "G3N2D2", "gene_name": "TSSK1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "G3N2D2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3N2D2" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "G3N2D2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3N2D2" } ] } ] }, { "uniprot_ac": "G3N2F6", "gene_name": "PIM3", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "G3N2F6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3N2F6" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "G3N2F6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3N2F6" } ] } ] }, { "uniprot_ac": "G3N2J4", "gene_name": "TTBK1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "G3N2J4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3N2J4" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "G3N2J4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3N2J4" } ] } ] }, { "uniprot_ac": "G5E518", "gene_name": "CDK12", "activity": [ { "ec_number": "2.7.11.22", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "G5E518", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G5E518" } ] }, { "ec_number": "2.7.11.23", "activity": "[DNA-directed RNA polymerase] + ATP = phospho-[DNA-directed RNA polymerase] + ADP + H(+).", "evidence": [ { "id": "G5E518", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G5E518" } ] }, { "ec_number": "2.7.11.22", "activity": "", "evidence": [ { "id": "G5E518", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G5E518" } ] }, { "ec_number": "2.7.11.23", "activity": "", "evidence": [ { "id": "G5E518", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G5E518" } ] } ] }, { "uniprot_ac": "G5E577", "gene_name": "MAPK6", "activity": [ { "ec_number": "2.7.11.24", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "G5E577", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G5E577" } ] }, { "ec_number": "2.7.11.24", "activity": "", "evidence": [ { "id": "G5E577", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G5E577" } ] } ] }, { "uniprot_ac": "G5E5A0", "gene_name": "STK17A", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "G5E5A0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G5E5A0" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "G5E5A0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G5E5A0" } ] } ] }, { "uniprot_ac": "G5E5D4", "gene_name": "MARK1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "G5E5D4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G5E5D4" } ] }, { "ec_number": "2.7.11.26", "activity": "L-seryl-[tau protein] + ATP = O-phospho-L-seryl-[tau protein] + ADP + H(+).", "evidence": [ { "id": "G5E5D4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G5E5D4" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "G5E5D4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G5E5D4" } ] }, { "ec_number": "2.7.11.26", "activity": "", "evidence": [ { "id": "G5E5D4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G5E5D4" } ] } ] }, { "uniprot_ac": "G5E5K2", "gene_name": "MASTL", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "G5E5K2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G5E5K2" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "G5E5K2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G5E5K2" } ] } ] }, { "uniprot_ac": "H2XJE8", "gene_name": "AAK1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "H2XJE8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/H2XJE8" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "H2XJE8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/H2XJE8" } ] } ] }, { "uniprot_ac": "H2XJE9", "gene_name": "NLK", "activity": [ { "ec_number": "2.7.11.24", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "H2XJE9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/H2XJE9" } ] }, { "ec_number": "2.7.11.24", "activity": "", "evidence": [ { "id": "H2XJE9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/H2XJE9" } ] } ] }, { "uniprot_ac": "P00516", "gene_name": "PRKG1", "activity": [ { "ec_number": "2.7.11.12", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "P00516", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P00516" } ] }, { "ec_number": "2.7.11.12", "activity": "", "evidence": [ { "id": "P00516", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P00516" } ] } ] }, { "uniprot_ac": "P00517", "gene_name": "PRKACA", "activity": [ { "ec_number": "2.7.11.11", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "P00517", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P00517" } ] }, { "ec_number": "2.7.11.11", "activity": "", "evidence": [ { "id": "P00517", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P00517" } ] } ] }, { "uniprot_ac": "P04409", "gene_name": "PRKCA", "activity": [ { "ec_number": "2.7.11.13", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "P04409", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P04409" } ] }, { "ec_number": "2.7.11.13", "activity": "", "evidence": [ { "id": "P04409", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P04409" } ] } ] }, { "uniprot_ac": "P05126", "gene_name": "PRKCB", "activity": [ { "ec_number": "2.7.11.13", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "P05126", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P05126" } ] }, { "ec_number": "2.7.11.13", "activity": "", "evidence": [ { "id": "P05126", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P05126" } ] } ] }, { "uniprot_ac": "P05128", "gene_name": "PRKCG", "activity": [ { "ec_number": "2.7.11.13", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "P05128", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P05128" } ] }, { "ec_number": "2.7.11.13", "activity": "", "evidence": [ { "id": "P05128", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P05128" } ] } ] }, { "uniprot_ac": "P05131", "gene_name": "PRKACB", "activity": [ { "ec_number": "2.7.11.11", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "P05131", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P05131" } ] }, { "ec_number": "2.7.11.11", "activity": "", "evidence": [ { "id": "P05131", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P05131" } ] } ] }, { "uniprot_ac": "P20427", "gene_name": "CSNK2A2", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "P20427", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P20427" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "P20427", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P20427" } ] } ] }, { "uniprot_ac": "P32871", "gene_name": "PIK3CA", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "P32871", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P32871" } ] }, { "ec_number": "2.7.1.153", "activity": "a 1,2-diacyl-sn-glycero-3-phospho-(1D-myo-inositol-4,5-bisphosphate) + ATP = a 1,2-diacyl-sn-glycero-3-phospho-(1D-myo-inositol-3,4,5-trisphosphate) + ADP + H(+).", "evidence": [ { "id": "P32871", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P32871" } ] }, { "ec_number": "2.7.1.137", "activity": "a 1,2-diacyl-sn-glycero-3-phospho-(1D-myo-inositol) + ATP = a 1,2-diacyl-sn-glycero-3-phospho-(1D-myo-inositol-3-phosphate) + ADP + H(+).", "evidence": [ { "id": "P32871", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P32871" } ] }, { "ec_number": "2.7.1.153", "activity": "", "evidence": [ { "id": "P32871", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P32871" } ] }, { "ec_number": "2.7.1.137", "activity": "", "evidence": [ { "id": "P32871", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P32871" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "P32871", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P32871" } ] } ] }, { "uniprot_ac": "P35507", "gene_name": "CSNK1B", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "P35507", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P35507" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "P35507", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P35507" } ] } ] }, { "uniprot_ac": "P35508", "gene_name": "CSNK1D", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "P35508", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P35508" } ] }, { "ec_number": "2.7.11.26", "activity": "L-seryl-[tau protein] + ATP = O-phospho-L-seryl-[tau protein] + ADP + H(+).", "evidence": [ { "id": "P35508", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P35508" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "P35508", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P35508" } ] } ] }, { "uniprot_ac": "P35509", "gene_name": "CSNK1G3", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "P35509", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P35509" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "P35509", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P35509" } ] } ] }, { "uniprot_ac": "P46196", "gene_name": "MAPK1", "activity": [ { "ec_number": "2.7.11.24", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "P46196", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P46196" } ] }, { "ec_number": "2.7.11.24", "activity": "", "evidence": [ { "id": "P46196", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P46196" } ] } ] }, { "uniprot_ac": "P48734", "gene_name": "CDK1", "activity": [ { "ec_number": "2.7.11.22", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "P48734", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P48734" } ] }, { "ec_number": "2.7.11.23", "activity": "[DNA-directed RNA polymerase] + ATP = phospho-[DNA-directed RNA polymerase] + ADP + H(+).", "evidence": [ { "id": "P48734", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P48734" } ] }, { "ec_number": "2.7.11.23", "activity": "", "evidence": [ { "id": "P48734", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P48734" } ] }, { "ec_number": "2.7.11.22", "activity": "", "evidence": [ { "id": "P48734", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P48734" } ] } ] }, { "uniprot_ac": "P52175", "gene_name": "NME1", "activity": [ { "ec_number": "3.1.11.-", "activity": "", "evidence": [ { "id": "P52175", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P52175" } ] }, { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "P52175", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P52175" } ] }, { "ec_number": "2.7.4.6", "activity": "UDP + ATP = UTP + ADP.", "evidence": [ { "id": "P52175", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P52175" } ] }, { "ec_number": "2.7.13.3", "activity": "ATP + protein L-histidine = ADP + protein N-phospho-L-histidine.", "evidence": [ { "id": "P52175", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P52175" } ] }, { "ec_number": "2.7.4.18", "activity": "(2E,6E)-farnesyl diphosphate + ATP = (2E,6E)-farnesyl triphosphate + ADP.", "evidence": [ { "id": "P52175", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P52175" } ] }, { "ec_number": "3.1.24.-", "activity": "", "evidence": [ { "id": "P52175", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P52175" } ] }, { "ec_number": "2.7.4.6", "activity": "", "evidence": [ { "id": "P52175", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P52175" } ] } ] }, { "uniprot_ac": "P67827", "gene_name": "CSNK1A1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "P67827", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P67827" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "P67827", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P67827" } ] } ] }, { "uniprot_ac": "P68399", "gene_name": "CSNK2A1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "P68399", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P68399" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "P68399", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P68399" } ] } ] }, { "uniprot_ac": "Q01314", "gene_name": "AKT1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "Q01314", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q01314" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "Q01314", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q01314" } ] } ] }, { "uniprot_ac": "Q02399", "gene_name": "CDK5", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "Q02399", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q02399" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "Q02399", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q02399" } ] } ] }, { "uniprot_ac": "Q08DZ2", "gene_name": "PRP4K", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "Q08DZ2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q08DZ2" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "Q08DZ2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q08DZ2" } ] } ] }, { "uniprot_ac": "Q08E52", "gene_name": "PAK1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "Q08E52", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q08E52" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "Q08E52", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q08E52" } ] } ] }, { "uniprot_ac": "Q0V7M1", "gene_name": "PSKH1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "Q0V7M1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q0V7M1" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "Q0V7M1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q0V7M1" } ] } ] }, { "uniprot_ac": "Q0VD22", "gene_name": "STK33", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "Q0VD22", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q0VD22" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "Q0VD22", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q0VD22" } ] } ] }, { "uniprot_ac": "Q17QV9", "gene_name": "STK40", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "Q17QV9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q17QV9" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "Q17QV9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q17QV9" } ] } ] }, { "uniprot_ac": "Q17R13", "gene_name": "TNK2", "activity": [ { "ec_number": "2.7.10.2", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "Q17R13", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q17R13" } ] }, { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "Q17R13", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q17R13" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "Q17R13", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q17R13" } ] }, { "ec_number": "2.7.10.2", "activity": "", "evidence": [ { "id": "Q17R13", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q17R13" } ] } ] }, { "uniprot_ac": "Q1RMT7", "gene_name": "RIOK3", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "Q1RMT7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q1RMT7" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "Q1RMT7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q1RMT7" } ] } ] }, { "uniprot_ac": "Q1RMT8", "gene_name": "IRAK4", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "Q1RMT8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q1RMT8" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "Q1RMT8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q1RMT8" } ] } ] }, { "uniprot_ac": "Q28021", "gene_name": "ROCK2", "activity": [ { "ec_number": "2.7.11.39", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "Q28021", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q28021" } ] }, { "ec_number": "2.7.11.39", "activity": "", "evidence": [ { "id": "Q28021", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q28021" } ] } ] }, { "uniprot_ac": "Q2HJF7", "gene_name": "CAMK2D", "activity": [ { "ec_number": "2.7.11.17", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "Q2HJF7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q2HJF7" } ] }, { "ec_number": "2.7.11.17", "activity": "", "evidence": [ { "id": "Q2HJF7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q2HJF7" } ] } ] }, { "uniprot_ac": "Q2KIP2", "gene_name": "HASPIN", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "Q2KIP2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q2KIP2" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "Q2KIP2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q2KIP2" } ] } ] }, { "uniprot_ac": "Q2KJG8", "gene_name": "BCKDK", "activity": [ { "ec_number": "2.7.11.-", "activity": "", "evidence": [ { "id": "Q2KJG8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q2KJG8" } ] }, { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "Q2KJG8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q2KJG8" } ] }, { "ec_number": "2.7.11.4", "activity": "L-seryl-[3-methyl-2-oxobutanoate dehydrogenase] + ATP = O-phospho-L-seryl-[3-methyl-2-oxobutanoate dehydrogenase] + ADP + H(+).", "evidence": [ { "id": "Q2KJG8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q2KJG8" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "Q2KJG8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q2KJG8" } ] } ] }, { "uniprot_ac": "Q2LGB3", "gene_name": "IRAK1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "Q2LGB3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q2LGB3" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "Q2LGB3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q2LGB3" } ] } ] }, { "uniprot_ac": "Q2TA06", "gene_name": "AURKA", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "Q2TA06", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q2TA06" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "Q2TA06", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q2TA06" } ] } ] }, { "uniprot_ac": "Q2TA25", "gene_name": "PLK1", "activity": [ { "ec_number": "2.7.11.21", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "Q2TA25", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q2TA25" } ] }, { "ec_number": "2.7.11.21", "activity": "", "evidence": [ { "id": "Q2TA25", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q2TA25" } ] } ] }, { "uniprot_ac": "Q2TBL8", "gene_name": "CDK10", "activity": [ { "ec_number": "2.7.11.22", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "Q2TBL8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q2TBL8" } ] }, { "ec_number": "2.7.11.22", "activity": "", "evidence": [ { "id": "Q2TBL8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q2TBL8" } ] } ] }, { "uniprot_ac": "Q2YDN8", "gene_name": "VRK3", "activity": [ { "ec_number": "2.7.11.22", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "Q2YDN8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q2YDN8" } ] }, { "ec_number": "2.7.11.22", "activity": "", "evidence": [ { "id": "Q2YDN8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q2YDN8" } ] } ] }, { "uniprot_ac": "Q32KY4", "gene_name": "CDK4", "activity": [ { "ec_number": "2.7.11.22", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "Q32KY4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q32KY4" } ] }, { "ec_number": "2.7.11.22", "activity": "", "evidence": [ { "id": "Q32KY4", "database": "UniProtKB", "url": 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"start_pos": 18600513, "end_pos": 18582844, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000007876.6", "url": "https://www.ensembl.org/id/ENSBTAT00000007876.6" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000007876.5", "url": "https://www.ensembl.org/id/ENSBTAP00000007876.5" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [ "enzyme" ], "publication": [], "pathway": [], "orthologs": [], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 6, "go_terms": [ { "name": "cytoplasm", "id": "GO:0005737", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005737", "evidence": [ { "database": "UniProtKB", "id": "F6QAN5", "url": "https://www.uniprot.org/uniprotkb/F6QAN5" } ], "pmid": "" }, { "name": "mitochondrion", "id": "GO:0005739", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005739", "evidence": [ { "database": "UniProtKB", "id": "F6QAN5", "url": "https://www.uniprot.org/uniprotkb/F6QAN5" } ], "pmid": "" }, { "name": "cytosol", "id": "GO:0005829", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005829", "evidence": [ { "database": "UniProtKB", "id": "F6QAN5", "url": "https://www.uniprot.org/uniprotkb/F6QAN5" } ], "pmid": "" }, { "name": "perinuclear region of cytoplasm", "id": "GO:0048471", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0048471", "evidence": [ { "database": "UniProtKB", "id": "F6QAN5", "url": "https://www.uniprot.org/uniprotkb/F6QAN5" } ], "pmid": "" }, { "name": "nuclear body", "id": "GO:0016604", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016604", "evidence": [ { "database": "UniProtKB", "id": "F6QAN5", "url": "https://www.uniprot.org/uniprotkb/F6QAN5" } ], "pmid": "" }, { "name": "P-body", "id": "GO:0000932", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000932", "evidence": [ { "database": "UniProtKB", "id": "F6QAN5", "url": "https://www.uniprot.org/uniprotkb/F6QAN5" } ], "pmid": "" } ] }, { "name": "Molecular Function", "total": 5, "go_terms": [ { "name": "metal ion binding", "id": "GO:0046872", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0046872", "evidence": [ { "database": "UniProtKB", "id": "F6QAN5", "url": "https://www.uniprot.org/uniprotkb/F6QAN5" } ], "pmid": "" }, { "name": "poly(A)-specific ribonuclease activity", "id": "GO:0004535", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0004535", "evidence": [ { "database": "UniProtKB", "id": "F6QAN5", "url": "https://www.uniprot.org/uniprotkb/F6QAN5" } ], "pmid": "" }, { "name": "mRNA binding", "id": "GO:0003729", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003729", "evidence": [ { "database": "UniProtKB", "id": "F6QAN5", "url": "https://www.uniprot.org/uniprotkb/F6QAN5" } ], "pmid": "" }, { "name": "NADP phosphatase activity", "id": "GO:0019178", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0019178", "evidence": [ { "database": "UniProtKB", "id": "F6QAN5", "url": "https://www.uniprot.org/uniprotkb/F6QAN5" } ], "pmid": "" }, { "name": "NADPH phosphatase activity", "id": 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"name": "negative regulation of gene expression", "id": "GO:0010629", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0010629", "evidence": [ { "database": "UniProtKB", "id": "F6QAN5", "url": "https://www.uniprot.org/uniprotkb/F6QAN5" } ], "pmid": "" }, { "name": "response to lipopolysaccharide", "id": "GO:0032496", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0032496", "evidence": [ { "database": "UniProtKB", "id": "F6QAN5", "url": "https://www.uniprot.org/uniprotkb/F6QAN5" } ], "pmid": "" }, { "name": "positive regulation of fat cell differentiation", "id": "GO:0045600", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0045600", "evidence": [ { "database": "UniProtKB", "id": "F6QAN5", "url": "https://www.uniprot.org/uniprotkb/F6QAN5" } ], "pmid": "" }, { "name": "mRNA stabilization", "id": "GO:0048255", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0048255", "evidence": [ { "database": "UniProtKB", "id": "F6QAN5", "url": "https://www.uniprot.org/uniprotkb/F6QAN5" } ], "pmid": "" }, { "name": "regulation of circadian rhythm", "id": "GO:0042752", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0042752", "evidence": [ { "database": "UniProtKB", "id": "F6QAN5", "url": "https://www.uniprot.org/uniprotkb/F6QAN5" } ], "pmid": "" }, { "name": "circadian regulation of gene expression", "id": "GO:0032922", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0032922", "evidence": [ { "database": "UniProtKB", "id": "F6QAN5", "url": "https://www.uniprot.org/uniprotkb/F6QAN5" } ], "pmid": "" }, { "name": "negative regulation of osteoblast differentiation", "id": "GO:0045668", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0045668", "evidence": [ { "database": "UniProtKB", "id": "F6QAN5", "url": "https://www.uniprot.org/uniprotkb/F6QAN5" } ], "pmid": "" }, { "name": "regulation of embryonic development", "id": "GO:0045995", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0045995", "evidence": [ { "database": "UniProtKB", "id": "F6QAN5", "url": "https://www.uniprot.org/uniprotkb/F6QAN5" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 172, "end_pos": 174, "annotation": "n_glycosylation_sequon" }, { "start_pos": 186, "end_pos": 188, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [ { "id": "28050", "name": "", "equation": "NADP(+) + H2O = phosphate + NAD(+)", "summary": "", "cellular_location": "", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [ "F6QAN5-1" ], "evidence": [ { "id": "28050", "database": "Rhea", "url": "https://www.rhea-db.org/rhea/28050" } ] }, { "id": "60664", "name": "", "equation": "NADPH + H2O = phosphate + NADH", "summary": "", "cellular_location": "", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [ "F6QAN5-1" ], "evidence": [ { "id": "60664", "database": "Rhea", "url": "https://www.rhea-db.org/rhea/60664" } ] } ], "reaction_participants": [], "reaction_enzymes": [ { "uniprot_ac": "F6QAN5", "gene_name": 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"NADPH + H2O = phosphate + NADH.", "evidence": [ { "id": "3.1.3.108", "database": "Rhea", "url": "https://www.rhea-db.org/rhea/?query=ec:3.1.3.108" }, { "id": "3.1.3.108", "database": "BRENDA Enzymes", "url": "https://www.brenda-enzymes.org/enzyme.php?ecno=3.1.3.108" } ] } ], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 172, "end_pos": 174 }, { "start_pos": 186, "end_pos": 188 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": 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"count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ], "tool_support": { "graph_view": "yes" } }, { "uniprot_canonical_ac": "F1N419-1", "uniprot_ac": "F1N419", "uniprot_id": "F1N419_BOVIN", "mass": { "chemical_mass": 42251.0, "monoisotopic_mass": 42251.0 }, "refseq": { "ac": "XP_002694571", "name": "signal peptide peptidase-like 3 isoform X1", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_002694571" }, "gene_names": [ { "name": "SPPL3", "type": "recommended", "evidence": [ { "id": "F1N419", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1N419" } ] }, { "name": "SPPL3", "type": "synonym", "evidence": [ { "id": "XP_002694571", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_002694571" } ] } ], "protein_names": [ { "name": "Signal peptide peptidase like 3", "type": "synonym", "evidence": [ { "id": "F1N419", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1N419/entry#names_and_taxonomy" } ] }, { "name": "signal peptide peptidase-like 3 isoform X1", "type": "synonym", "evidence": [ { "id": "XP_002694571", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_002694571" } ] } ], "function": [], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Bos taurus", "taxid": 9913, "evidence": [ { "database": "UniProtKB", "id": "F1N419", "url": "https://www.uniprot.org/uniprotkb/F1N419" } ], "common_name": "Bovine", "glygen_name": "Bovine", "reference_species": "Bos taurus [9913]" } ], "gene": [ { "name": "SPPL3", "url": "https://www.uniprot.org/uniprotkb/F1N419", "locus": { "chromosome": "17", "start_pos": 63027440, "end_pos": 63121362, "strand": "+", "evidence": [ { "database": "Ensembl Gene", "id": "ENSBTAG00000016338", "url": "https://www.ensembl.org/id/ENSBTAG00000016338" } ] } } ], "crossref": [ { "id": "F1N419", "url": "https://alphafold.ebi.ac.uk/entry/F1N419", "database": "AlphaFoldDB", "categories": [] }, { "id": "ENSBTAG00000016338", "url": "https://bgee.org/?page=gene&gene_id=ENSBTAG00000016338", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "535156", "url": "https://www.ncbi.nlm.nih.gov/gene/535156", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR006639", "url": "https://www.ebi.ac.uk/interpro/entry/IPR006639", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR007369", "url": "https://www.ebi.ac.uk/interpro/entry/IPR007369", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "bta:535156", "url": "https://www.genome.jp/dbget-bin/www_bget?bta:535156", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "VDYQWAY", "url": "https://omabrowser.org/oma/group/VDYQWAY/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "F1N419", "url": "https://www.orthodb.org/?gene=F1N419", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "G3MWR0", "url": "https://www.orthodb.org/?gene=G3MWR0", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR12174", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR12174", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR12174:SF22", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR12174:SF22", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF04258", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF04258", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "XP_002694571", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_002694571", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0AAA9SKK6", "url": "https://www.uniprot.org/uniprotkb/A0AAA9SKK6", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0AAA9SKK6-1", "url": "https://www.uniprot.org/uniprotkb/A0AAA9SKK6-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0AAA9SU36", "url": "https://www.uniprot.org/uniprotkb/A0AAA9SU36", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0AAA9SU36-1", "url": "https://www.uniprot.org/uniprotkb/A0AAA9SU36-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0AAA9TIT7", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TIT7", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0AAA9TIT7-1", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TIT7-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0AAA9TPH3", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TPH3", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0AAA9TPH3-1", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TPH3-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "F1N419", "url": "https://www.uniprot.org/uniprotkb/F1N419", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "F1N419-1", "url": "https://www.uniprot.org/uniprotkb/F1N419-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "G3MWR0", "url": "https://www.uniprot.org/uniprotkb/G3MWR0", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "G3MWR0-1", "url": "https://www.uniprot.org/uniprotkb/G3MWR0-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MAEQTYSWAYSLVDSSQVSTFLISILLIVYGSFRSLNMDFENQDKEKDSNSSSGSFNGNSTNNSIQTIDSTQALFLPIGASVSLLVMFFFFDSVQVVFTICTAVLATIAFAFLLLPMCQYLTRPCSPQNKISFGCCGRFTAAELLSFSLSVMLVLIWVLTGHWLLMDALAMGLCVAMIAFVRLPSLKVSCLLLSGLLIYDVFWVFFSAYIFNSNVMVKVATQPADNPLDVLSRKLHLGPNVGRDVPRLSLPGKLVFPSSTGSHFSMLGIGDIVMPGLLLCFVLRYDNYKKQASGDSCGASGPANISGRMQKVSYFHCTLIGYFVGLLTATVASRIHRAAQPALLYLVPFTLLPLLTMAYLKGDLRRMWSEPFHSKSSSSRFLEV", "length": 384, "header": "tr|F1N419-1|F1N419_BOVIN Isoform 1 of Signal peptide peptidase like 3 OS=Bos taurus OX=9913 GN=SPPL3 PE=3 SV=2 CANONICAL=F1N419-1" }, "isoforms": [ { "isoform_ac": "A0AAA9SKK6-1", "url": "https://www.uniprot.org/uniprotkb/A0AAA9SKK6/entry", "sequence": { "sequence": "MVVSGFSNHKNHLGKAVRSLNMDFENQDKEKDSNSSSGSFNGNSTNNSIQTIDSTQALFLPIGASVSLLVMFFFFDSVQVVFTICTAVLATIAFAFLLLPMCQYLTRPCSPQNKISFGCCGRFTAAELLSFSLSVMLVLIWVLTGHWLLMDALAMGLCVAMIAFVRLPSLKVSCLLLSGLLIYDVFWVFFSAYIFNSNVMVKVATQPADNPLDVLSRKLHLGPNVGRDVPRLSLPGKLVFPSSTGSHFSMLGIGDIVMPGLLLCFVLRYDNYKKQASGDSCGASGPANISGRMQKVSYFHCTLIGYFVGLLTATVASRIHRAAQPALLYLVPFTLLPLLTMAYLKGDLRRMWSEPFHSKSSSSRFLEV", "length": 368, "header": "tr|A0AAA9SKK6-1|F1N419_BOVIN Computationally mapped isoform of Signal peptide peptidase like 3 OS=Bos taurus OX=9913 GN=SPPL3 PE=3 SV=1 CANONICAL=F1N419-1" }, "locus": { "chromosome": "17", "start_pos": 63058036, "end_pos": 63028444, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000123674.1", "url": "https://www.ensembl.org/id/ENSBTAT00000123674.1" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000085823.1", "url": "https://www.ensembl.org/id/ENSBTAP00000085823.1" } ] } }, { "isoform_ac": "A0AAA9SU36-1", "url": "https://www.uniprot.org/uniprotkb/A0AAA9SU36/entry", "sequence": { "sequence": "MAEQTYSWSLNMDFENQDKEKDSNSSSGSFNGNSTNNSIQTIDSTQALFLPIGASVSLLVMFFFFDSVQVVFTICTAVLATIAFAFLLLPMCQYLTRPCSPQNKISFGCCGRFTAAELLSFSLSVMLVLIWVLTGHWLLMDALAMGLCVAMIAFVRLPSLKVSCLLLSGLLIYDVFWVFFSAYIFNSNVMVKVATQPADNPLDVLSRKLHLGPNVGRDVPRLSLPGKLVFPSSTGSHFSMLGIGDIVMPGLLLCFVLRYDNYKKQASGDSCGASGPANISGRMQKVSYFHCTLIGYFVGLLTATVASRIHRAAQPALLYLVPFTLLPLLTMAYLKGDLRRMWSEPFHSKSSSSRFLEV", "length": 358, "header": "tr|A0AAA9SU36-1|F1N419_BOVIN Computationally mapped isoform of Signal peptide peptidase like 3 OS=Bos taurus OX=9913 GN=SPPL3 PE=3 SV=1 CANONICAL=F1N419-1" }, "locus": { "chromosome": "17", "start_pos": 63121163, "end_pos": 63028444, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000114311.1", "url": "https://www.ensembl.org/id/ENSBTAT00000114311.1" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000087662.1", "url": "https://www.ensembl.org/id/ENSBTAP00000087662.1" } ] } }, { "isoform_ac": "A0AAA9TIT7-1", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TIT7/entry", "sequence": { "sequence": "MDSHGHSGTDPRREAAGKEEWTRWRGAGRGKGGVHRAERHLLGTGDTRSNLEVVREEEPPPLGLPLTPGMGSEGKSWCGGQRPRREQRKAAEGESPRNPGGYPLLKRAYSLVDSSQVSTFLISILLIVYGSFRSLNMDFENQDKEKDSNSSSGSFNGNSTNNSIQTIDSTQALFLPIGASVSLLVMFFFFDSVQVVFTICTAVLATIAFAFLLLPMCQYLTRPCSPQNKISFGCCGRFTAAELLSFSLSVMLVLIWVLTGHWLLMDALAMGLCVAMIAFVRLPSLKVSCLLLSGLLIYDVFWVFFSAYIFNSNVMVKVATQPADNPLDVLSRKLHLGPNVGRDVPRLSLPGKLVFPSSTGSHFSMLGIGDIVMPGLLLCFVLRYDNYKKQASGDSCGASGPANISGRMQKVSYFHCTLIGYFVGLLTATVASRIHRAAQPALLYLVPFTLLPLLTMAYLKGDLRRMWSEPFHSKSSSSRFLEV", "length": 483, "header": "tr|A0AAA9TIT7-1|F1N419_BOVIN Computationally mapped isoform of Signal peptide peptidase like 3 OS=Bos taurus OX=9913 GN=SPPL3 PE=3 SV=1 CANONICAL=F1N419-1" }, "locus": { "chromosome": "17", "start_pos": 63120814, "end_pos": 63028444, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000130547.1", "url": "https://www.ensembl.org/id/ENSBTAT00000130547.1" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000097059.1", "url": "https://www.ensembl.org/id/ENSBTAP00000097059.1" } ] } }, { "isoform_ac": "A0AAA9TPH3-1", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TPH3/entry", "sequence": { "sequence": "MLRFLCFVVRVAAGAYSLVDSSQVSTFLISILLIVYGSFRSLNMDFENQDKEKDSNSSSGSFNGNSTNNSIQTIDSTQALFLPIGASVSLLVMFFFFDSVQVVFTICTAVLATIAFAFLLLPMCQYLTRPCSPQNKISFGCCGRFTAAELLSFSLSVMLVLIWVLTGHWLLMDALAMGLCVAMIAFVRLPSLKVSCLLLSGLLIYDVFWVFFSAYIFNSNVMVKVATQPADNPLDVLSRKLHLGPNVGRDVPRLSLPGKLVFPSSTGSHFSMLGIGDIVMPGLLLCFVLRYDNYKKQASGDSCGASGPANISGRMQKVSYFHCTLIGYFVGLLTATVASRIHRAAQPALLYLVPFTLLPLLTMAYLKGDLRRMWSEPFHSKSSSSRFLEV", "length": 390, "header": "tr|A0AAA9TPH3-1|F1N419_BOVIN Computationally mapped isoform of Signal peptide peptidase like 3 OS=Bos taurus OX=9913 GN=SPPL3 PE=3 SV=1 CANONICAL=F1N419-1" }, "locus": { "chromosome": "17", "start_pos": 63074438, "end_pos": 63028444, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000135377.1", "url": "https://www.ensembl.org/id/ENSBTAT00000135377.1" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000100295.1", "url": "https://www.ensembl.org/id/ENSBTAP00000100295.1" } ] } }, { "isoform_ac": "F1N419-1", "url": "https://www.uniprot.org/uniprotkb/F1N419/entry", "sequence": { "sequence": "MAEQTYSWAYSLVDSSQVSTFLISILLIVYGSFRSLNMDFENQDKEKDSNSSSGSFNGNSTNNSIQTIDSTQALFLPIGASVSLLVMFFFFDSVQVVFTICTAVLATIAFAFLLLPMCQYLTRPCSPQNKISFGCCGRFTAAELLSFSLSVMLVLIWVLTGHWLLMDALAMGLCVAMIAFVRLPSLKVSCLLLSGLLIYDVFWVFFSAYIFNSNVMVKVATQPADNPLDVLSRKLHLGPNVGRDVPRLSLPGKLVFPSSTGSHFSMLGIGDIVMPGLLLCFVLRYDNYKKQASGDSCGASGPANISGRMQKVSYFHCTLIGYFVGLLTATVASRIHRAAQPALLYLVPFTLLPLLTMAYLKGDLRRMWSEPFHSKSSSSRFLEV", "length": 384, "header": "tr|F1N419-1|F1N419_BOVIN Isoform 1 of Signal peptide peptidase like 3 OS=Bos taurus OX=9913 GN=SPPL3 PE=3 SV=2 CANONICAL=F1N419-1" }, "locus": { "chromosome": "17", "start_pos": 63121163, "end_pos": 63028444, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000021732.6", "url": "https://www.ensembl.org/id/ENSBTAT00000021732.6" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000021732.5", "url": "https://www.ensembl.org/id/ENSBTAP00000021732.5" } ] } }, { "isoform_ac": "G3MWR0-1", "url": "https://www.uniprot.org/uniprotkb/G3MWR0/entry", "sequence": { "sequence": "MDFENQDKEKDSNSSSGSFNGNSTNNSIQTIDSTQALFLPIGASVSLLVMFFFFDSVQVVFTICTAVLATIAFAFLLLPMCQYLTRPCSPQNKISFGCCGRFTAAELLSFSLSVMLVLIWVLTGHWLLMDALAMGLCVAMIAFVRLPSLKVSCLLLSGLLIYDVFWVFFSAYIFNSNVMVKVATQPADNPLDVLSRKLHLGPNVGRDVPRLSLPGKLVFPSSTGSHFSMLGIGDIVMPGLLLCFVLRYDNYKKQASGDSCGASGPANISGRMQKVSYFHCTLIGYFVGLLTATVASRIHRAAQPALLYLVPFTLLPLLTMAYLKGDLRRMWSEPFHSKSSSSRFLEV", "length": 347, "header": "tr|G3MWR0-1|G3MWR0_BOVIN Computationally mapped isoform of Signal peptide peptidase like 3 OS=Bos taurus OX=9913 GN=SPPL3 PE=3 SV=3 CANONICAL=F1N419-1" }, "locus": { "chromosome": "17", "start_pos": 63042678, "end_pos": 63028444, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000065435.3", "url": "https://www.ensembl.org/id/ENSBTAT00000065435.3" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000053963.3", "url": "https://www.ensembl.org/id/ENSBTAP00000053963.3" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [ { "id": "bta:535156", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?bta:535156", "resource": "KEGG Pathway" } ], "orthologs": [ { "uniprot_canonical_ac": "A0ABK0LIZ0-1", "protein_name": "Signal peptide peptidase like 3", "gene_name": "Sppl3", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MAEQTYSWAYSLVDSSQVSTFLISILLIVYGSFRSLNMDFENQDKEKDSSSSSGPFNGSSTNNSIQTIDSTQALFLPIGASVSLLVMFFFFDSVQVVFTICTAVLATIAFAFLLLPMCQYLTRPCSPQNKISFGCCGRFTAAELLSFSLSVMLVLIWVLTGHWLLMDALAMGLCVAMIAFVRLPSLKVSCLLLSGLLIYDVFWVFFSAYIFNSNVMVKVATQPADNPLDVLSRKLHLGPNVGRDVPRLSLPGKLVFPSSTGSHFSMLGIGDIVMPGLLLCFVLRYDNYKKQASGDSCGAPGPANISGRMQRVSYFHCTLIGYFVGLLTATVASRIHRAAQPALLYLVPFTLLPLLTMAYLKGDLRRMWSEPFHSKSSSSRFLEV", "length": 384 }, "evidence": [ { "id": "F1N419", "url": "https://omabrowser.org/oma/group/F1N419/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "F1RJH1-1", "protein_name": "Signal peptide peptidase like 3", "gene_name": "SPPL3", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MAEQTYSWAYSLVDSSQVSTFLISILLIVYGSFRSLNMDFENQDKEKDNNSSSGSFNGNSTNNSIQTIDSTQALFLPIGASVSLLVMFFFFDSVQVVFTICTAVLATIAFAFLLLPMCQYLTRPCSPQNKISFGCCGRFTAAELLSFSLSVMLVLIWVLTGHWLLMDALAMGLCVAMIAFVRLPSLKVSCLLLSGLLIYDVFWVFFSAYIFNSNVMVKVATQPADNPLDVLSRKLHLGPNVGRDVPRLSLPGKLVFPSSTGSHFSMLGIGDIVMPGLLLCFVLRYDNYKKQANGDSCSASGPANISGRMQKVSYFHCTLIGYFVGLLTATVASRIHRAAQPALLYLVPFTLLPLLTMAYLKGDLRRMWSEPFHSKSSSSRFLEV", "length": 384 }, "evidence": [ { "id": "F1N419", "url": "https://omabrowser.org/oma/group/F1N419/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "Q86P97-1", "protein_name": "Signal peptide peptidase-like", "gene_name": "SppL", "tax_id": 7227, "organism": "Drosophila melanogaster", "sequence": { "sequence": "MSHGGAGGGLGAQTVGAGQLGGGAAAAGGGEYRELHWTVSSVMDSSRVSTCLISMLLIVYGSFRSLNIEQEAREREQKKRNESMTNLLTGEPVEKEPNLYFTADKFATLDTMHALCLPLGASISLLIMFFFFDSMQLLFAVCTAIIATVALAFLLLPMCQYIIRPCTDGKRFSFGFCGRFTAAELFSFTLSVSIVCIWVLTGHWLLMDAMGMGLCVAFIAFVRLPSLKVSTLLLTGLLIYDVFWVFLSSYIFSTNVMVKVATRPADNPVGIVARKLHLGGIVRDTPKLNLPGKLVFPSLHNTGHFSMLGLGDVVMPGLLLCFVLRYDAYKKAQGVTSDPTLSPPRGVGSRLTYFHCSLLGYFLGLLTATVSSEVFKAAQPALLYLVPFTLLPLLLMAYLKGDLRRMWSEPFIAQQPSKQLEV", "length": 422 }, "evidence": [ { "id": "F1N419", "url": "https://omabrowser.org/oma/group/F1N419/", "database": "OMA" } ], "glygen_name": "Fruit fly", "common_name": "Fruit fly" }, { "uniprot_canonical_ac": "Q8TCT6-2", "protein_name": "Signal peptide peptidase-like 3", "gene_name": "SPPL3", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MAEQTYSWAYSLVDSSQVSTFLISILLIVYGSFRSLNMDFENQDKEKDSNSSSGSFNGNSTNNSIQTIDSTQALFLPIGASVSLLVMFFFFDSVQVVFTICTAVLATIAFAFLLLPMCQYLTRPCSPQNKISFGCCGRFTAAELLSFSLSVMLVLIWVLTGHWLLMDALAMGLCVAMIAFVRLPSLKVSCLLLSGLLIYDVFWVFFSAYIFNSNVMVKVATQPADNPLDVLSRKLHLGPNVGRDVPRLSLPGKLVFPSSTGSHFSMLGIGDIVMPGLLLCFVLRYDNYKKQASGDSCGAPGPANISGRMQKVSYFHCTLIGYFVGLLTATVASRIHRAAQPALLYLVPFTLLPLLTMAYLKGDLRRMWSEPFHSKSSSSRFLEV", "length": 384 }, "evidence": [ { "id": "F1N419", "url": "https://omabrowser.org/oma/group/F1N419/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "Q93Z32-1", "protein_name": "Signal peptide peptidase-like 1", "gene_name": "SPPL1", "tax_id": 3702, "organism": "Arabidopsis thaliana", "sequence": { "sequence": "METLWTLLYLLEPAPATLIVTAVTVTFASAFRALNYGKEMERNRDFSEASITLDSSQALMIPVMSSCSLLLMFYLFSSVSQLLTAFTAIASVSSLFYWLSPYAVYMKTQLGLSDPFLSRCCSKSFTRIQGLLLVACAMTVVAWLISGHWVLNNLLGISICIAFVSHVRLPNIKICAMLLVCLFVYDIFWVFFSERFFGANVMVAVATQQASNPVHTVANSLNLPGLQLITKKLELPVKIVFPRNLLGGVVPGVSASDFMMLGLGDMAIPAMLLALVLCFDHRKTRDVVNIFDLKSSKGHKYIWYALPGYAIGLVAALAAGVLTHSPQPALLYLVPSTLGPVIFMSWRRKDLAELWEGPALSNPIEKSHEIEI", "length": 372 }, "evidence": [ { "id": "F1N419", "url": "https://omabrowser.org/oma/group/F1N419/", "database": "OMA" } ], "glygen_name": "Arabidopsis", "common_name": "Mouse-ear cress" }, { "uniprot_canonical_ac": "Q9CUS9-1", "protein_name": "Signal peptide peptidase-like 3", "gene_name": "Sppl3", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MAEQTYSWAYSLVDSSQVSTFLISILLIVYGSFRSLNMDFENQDKEKDSNSSSGSFNGNSTNNSIQTIDSTQALFLPIGASVSLLVMFFFFDSVQVVFTICTAVLATIAFAFLLLPMCQYLTRPCSPQNKISFGCCGRFTAAELLSFSLSVMLVLIWVLTGHWLLMDALAMGLCVAMIAFVRLPSLKVSCLLLSGLLIYDVFWVFFSAYIFNSNVMVKVATQPADNPLDVLSRKLHLGPNVGRDVPRLSLPGKLVFPSSTGSHFSMLGIGDIVMPGLLLCFVLRYDNYKKQASGDSCGAPGPANISGRMQKVSYFHCTLIGYFVGLLTATVASRIHRAAQPALLYLVPFTLLPLLTMAYLKGDLRRMWSEPFHSKSSSSRFLEV", "length": 384 }, "evidence": [ { "id": "F1N419", "url": "https://omabrowser.org/oma/group/F1N419/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" } ], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 8, "go_terms": [ { "name": "endomembrane system", "id": "GO:0012505", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0012505", "evidence": [ { "database": "UniProtKB", "id": "F1N419", "url": "https://www.uniprot.org/uniprotkb/F1N419" } ], "pmid": "" }, { "name": "organelle membrane", "id": "GO:0031090", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0031090", "evidence": [ { "database": "UniProtKB", "id": "F1N419", "url": "https://www.uniprot.org/uniprotkb/F1N419" } ], "pmid": "" }, { "name": "cytoplasmic side of endoplasmic reticulum membrane", "id": "GO:0098554", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0098554", "evidence": [ { "database": "UniProtKB", "id": "F1N419", "url": "https://www.uniprot.org/uniprotkb/F1N419" } ], "pmid": "" }, { "name": "rough endoplasmic reticulum", "id": "GO:0005791", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005791", "evidence": [ { "database": "UniProtKB", "id": "F1N419", "url": "https://www.uniprot.org/uniprotkb/F1N419" } ], "pmid": "" }, { "name": "plasma membrane", "id": "GO:0005886", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005886", "evidence": [ { "database": "UniProtKB", "id": "F1N419", "url": "https://www.uniprot.org/uniprotkb/F1N419" } ], "pmid": "" }, { "name": "endoplasmic reticulum-Golgi intermediate compartment membrane", "id": "GO:0033116", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0033116", "evidence": [ { "database": "UniProtKB", "id": "F1N419", "url": "https://www.uniprot.org/uniprotkb/F1N419" } ], "pmid": "" }, { "name": "Golgi-associated vesicle membrane", "id": "GO:0030660", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030660", "evidence": [ { "database": "UniProtKB", "id": "F1N419", "url": "https://www.uniprot.org/uniprotkb/F1N419" } ], "pmid": "" }, { "name": "lumenal side of endoplasmic reticulum membrane", "id": "GO:0098553", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0098553", "evidence": [ { "database": "UniProtKB", "id": "F1N419", "url": "https://www.uniprot.org/uniprotkb/F1N419" } ], "pmid": "" } ] }, { "name": "Molecular Function", "total": 2, "go_terms": [ { "name": "aspartic endopeptidase activity, intramembrane cleaving", "id": "GO:0042500", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0042500", "evidence": [ { "database": "UniProtKB", "id": "F1N419", "url": "https://www.uniprot.org/uniprotkb/F1N419" } ], "pmid": "" }, { "name": "protein homodimerization activity", "id": "GO:0042803", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0042803", "evidence": [ { "database": "UniProtKB", "id": "F1N419", "url": "https://www.uniprot.org/uniprotkb/F1N419" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 4, "go_terms": [ { "name": "positive regulation of cytosolic calcium ion concentration", "id": "GO:0007204", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007204", "evidence": [ { "database": "UniProtKB", "id": "F1N419", "url": "https://www.uniprot.org/uniprotkb/F1N419" } ], "pmid": "" }, { "name": "T cell receptor signaling pathway", "id": "GO:0050852", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0050852", "evidence": [ { "database": "UniProtKB", "id": "F1N419", "url": "https://www.uniprot.org/uniprotkb/F1N419" } ], "pmid": "" }, { "name": "positive regulation of calcineurin-NFAT signaling cascade", "id": "GO:0070886", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0070886", "evidence": [ { "database": "UniProtKB", "id": "F1N419", "url": "https://www.uniprot.org/uniprotkb/F1N419" } ], "pmid": "" }, { "name": "membrane protein proteolysis", "id": "GO:0033619", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0033619", "evidence": [ { "database": "UniProtKB", "id": "F1N419", "url": "https://www.uniprot.org/uniprotkb/F1N419" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 304, "end_pos": 306, "annotation": "n_glycosylation_sequon" }, { "start_pos": 50, "end_pos": 52, "annotation": "n_glycosylation_sequon" }, { "start_pos": 59, "end_pos": 61, "annotation": "n_glycosylation_sequon" }, { "start_pos": 62, "end_pos": 64, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], 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"https://www.uniprot.org/uniprotkb/F1N670" } ] }, { "name": "IKZF4", "type": "synonym", "evidence": [ { "id": "NP_001179693", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001179693" } ] }, { "name": "ZNFN1A4", "type": "synonym", "evidence": [ { "id": "NP_001179693", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001179693" } ] } ], "protein_names": [ { "name": "IKAROS family zinc finger 4", "type": "synonym", "evidence": [ { "id": "F1N670", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1N670/entry#names_and_taxonomy" } ] }, { "name": "zinc finger protein Eos", "type": "synonym", "evidence": [ { "id": "NP_001179693", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001179693" } ] }, { "name": "zinc finger protein, subfamily 1A, 4", "type": "synonym", "evidence": [ { "id": "NP_001179693", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001179693" } ] } ], "function": [], 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"https://www.ncbi.nlm.nih.gov/gene/540671", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR013087", "url": "https://www.ebi.ac.uk/interpro/entry/IPR013087", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR036236", "url": "https://www.ebi.ac.uk/interpro/entry/IPR036236", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR050589", "url": "https://www.ebi.ac.uk/interpro/entry/IPR050589", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "bta:540671", "url": "https://www.genome.jp/dbget-bin/www_bget?bta:540671", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "LCGMVCI", "url": "https://omabrowser.org/oma/group/LCGMVCI/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "F1N670", "url": "https://www.orthodb.org/?gene=F1N670", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR24404", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR24404", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR24404:SF28", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR24404:SF28", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00096", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00096", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "NP_001179693", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001179693", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0AAA9SMW9", "url": "https://www.uniprot.org/uniprotkb/A0AAA9SMW9", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0AAA9SMW9-1", "url": "https://www.uniprot.org/uniprotkb/A0AAA9SMW9-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0AAA9T6Y1", "url": "https://www.uniprot.org/uniprotkb/A0AAA9T6Y1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0AAA9T6Y1-1", "url": "https://www.uniprot.org/uniprotkb/A0AAA9T6Y1-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0AAA9TEE6", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TEE6", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0AAA9TEE6-1", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TEE6-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0AAA9TGU9", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TGU9", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0AAA9TGU9-1", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TGU9-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0AAA9TKI2", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TKI2", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0AAA9TKI2-1", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TKI2-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "F1N670", "url": "https://www.uniprot.org/uniprotkb/F1N670", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "F1N670-1", "url": "https://www.uniprot.org/uniprotkb/F1N670-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MHTPPALARRFQGGGRARTPGSQRQGKDNLERDPSGGCVPDFLPQAQDSNHFIMESLFCESSGDSSLEKEFLGAPVGPSVSTPNSQHSSPSRSLSANSIKVEMYSDEESSRLLGPDERLLEKDDSVIVEDSLSEPLGYCDGSGPEPHSPGGIRLPNGKLKCDVCGMVCIGPNVLMVHKRSHTGERPFHCNQCGASFTQKGNLLRHIKLHSGEKPFKCPFCNYACRRRDALTGHLRTHSVSSPTVGKPYKCNYCGRSYKQQSTLEEHKERCHNYLQSLSTEAQALAGQSGDEIRDLEMVPDSMLHSSSERPTFIDRLANSLTKRKRSTPQKFVGEKQMRFSLSDLPYDVNSGGYEKDVELVAHHGLEPGFGGSLAFVGAEHLRPLRLPPTNCISELTPVISSVYTQMQPLPGRLELPGSREAGEGPEDLADGGPLLYRARGPLTDPGASPSNGCQDSTDTESNHEDRVGGVVSLPQGPPPQPPPAVVVGRPSPAYAKEDPKPQEGLLRGTPGPSKEVLRVVGESGEPVKAFKCEHCRILFLDHVMFTIHMGCHGFRDPFECNICGYHSQDRYEFSSHIVRGEHKVG", "length": 585, "header": "tr|F1N670-1|F1N670_BOVIN Isoform 1 of IKAROS family zinc finger 4 OS=Bos taurus OX=9913 GN=IKZF4 PE=3 SV=2 CANONICAL=F1N670-1" }, "isoforms": [ { "isoform_ac": "A0AAA9SMW9-1", "url": "https://www.uniprot.org/uniprotkb/A0AAA9SMW9/entry", "sequence": { "sequence": "MTAVPLTSRNPRFLEGSGDSSLEKEFLGAPVGPSVSTPNSQHSSPSRSLSANSIKVEMYSDEESSRLLGPDERLLEKDDSVIVEDSLSEPLGYCDGSGPEPHSPGGIRLPNGKLKCDVCGMVCIGPNVLMVHKRSHTGERPFHCNQCGASFTQKGNLLRHIKLHSGEKPFKCPFCNYACRRRDALTGHLRTHSVSSPTVGKPYKCNYCGRSYKQQSTLEEHKERCHNYLQSLSTEAQALAGQSGDEIRDLEMVPDSMLHSSSERPTFIDRLANSLTKRKRSTPQKFVGEKQMRFSLSDLPYDVNSGGYEKDVELVAHHGLEPGFGGSLAFVGAEHLRPLRLPPTNCISELTPVISSVYTQMQPLPGRLELPGSREAGEGPEDLADGGPLLYRARGPLTDPGASPSNGCQDSTDTESNHEDRVGGVVSLPQGPPPQPPPAVVVGRPSPAYAKEDPKPQEGLLRGTPGPSKEVLRVVGESGEPVKAFKCEHCRILFLDHVMFTIHMGCHGFRDPFECNICGYHSQDRYEFSSHIVRGEHKVG", "length": 540, "header": "tr|A0AAA9SMW9-1|F1N670_BOVIN Computationally mapped isoform of IKAROS family zinc finger 4 OS=Bos taurus OX=9913 GN=IKZF4 PE=3 SV=1 CANONICAL=F1N670-1" }, "locus": { "chromosome": "5", "start_pos": 57302892, "end_pos": 57292531, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000115932.2", "url": "https://www.ensembl.org/id/ENSBTAT00000115932.2" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000085235.1", "url": "https://www.ensembl.org/id/ENSBTAP00000085235.1" } ] } }, { "isoform_ac": "A0AAA9T6Y1-1", "url": "https://www.uniprot.org/uniprotkb/A0AAA9T6Y1/entry", "sequence": { "sequence": "MLAAIIMITIIIIRFRDNSSCPSCRSRIQCRGLRRVTVGKNVCPELPPSQGPHFPLHPGPPSPSPASCGRQAVMLFPSGLDEGSGDSSLEKEFLGAPVGPSVSTPNSQHSSPSRSLSANSIKVEMYSDEESSRLLGPDERLLEKDDSVIVEDSLSEPLGYCDGSGPEPHSPGGIRLPNGKLKCDVCGMVCIGPNVLMVHKRSHTGERPFHCNQCGASFTQKGNLLRHIKLHSGEKPFKCPFCNYACRRRDALTGHLRTHSVSSPTVGKPYKCNYCGRSYKQQSTLEEHKERCHNYLQSLSTEAQALAGQSGDEIRDLEMVPDSMLHSSSERPTFIDRLANSLTKRKRSTPQKFVGEKQMRFSLSDLPYDVNSGGYEKDVELVAHHGLEPGFGGSLAFVGAEHLRPLRLPPTNCISELTPVISSVYTQMQPLPGRLELPGSREAGEGPEDLADGGPLLYRARGPLTDPGASPSNGCQDSTDTESNHEDRVGGVVSLPQGPPPQPPPAVVVGRPSPAYAKEDPKPQEGLLRGTPGPSKEVLRVVGESGEPVKAFKCEHCRILFLDHVMFTIHMGCHGFRDPFECNICGYHSQDRYEFSSHIVRGEHKVG", "length": 607, "header": "tr|A0AAA9T6Y1-1|F1N670_BOVIN Computationally mapped isoform of IKAROS family zinc finger 4 OS=Bos taurus OX=9913 GN=IKZF4 PE=3 SV=1 CANONICAL=F1N670-1" }, "locus": { "chromosome": "5", "start_pos": 57300072, "end_pos": 57292531, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000092972.1", "url": "https://www.ensembl.org/id/ENSBTAT00000092972.1" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000092511.1", "url": "https://www.ensembl.org/id/ENSBTAP00000092511.1" } ] } }, { "isoform_ac": "A0AAA9TEE6-1", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TEE6/entry", "sequence": { "sequence": "MLFPSGLDEGSGDSSLEKEFLGAPVGPSVSTPNSQHSSPSRSLSANSIKVEMYSDEESSRLLGPDERLLEKDDSVIVEDSLSEPLGYCDGSGPEPHSPGGIRLPNGKLKCDVCGMVCIGPNVLMVHKRSHTGERPFHCNQCGASFTQKGNLLRHIKLHSGEKPFKCPFCNYACRRRDALTGHLRTHSVSSPTVGKPYKCNYCGRSYKQQSTLEEHKERCHNYLQSLSTEAQALAGQSGDEIRDLEMVPDSMLHSSSERPTFIDRLANSLTKRKRSTPQKFVGEKQMRFSLSDLPYDVNSGGYEKDVELVAHHGLEPGFGGSLAFVGAEHLRPLRLPPTNCISELTPVISSVYTQMQPLPGRLELPGSREAGEGPEDLADGGPLLYRARGPLTDPGASPSNGCQDSTDTESNHEDRVGGVVSLPQGPPPQPPPAVVVGRPSPAYAKEDPKPQEGLLRGTPGPSKEVLRVVGESGEPVKAFKCEHCRILFLDHVMFTIHMGCHGFRDPFECNICGYHSQDRYEFSSHIVRGEHKVG", "length": 534, "header": "tr|A0AAA9TEE6-1|F1N670_BOVIN Computationally mapped isoform of IKAROS family zinc finger 4 OS=Bos taurus OX=9913 GN=IKZF4 PE=3 SV=1 CANONICAL=F1N670-1" }, "locus": { "chromosome": "5", "start_pos": 57299853, "end_pos": 57292531, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000111936.1", "url": "https://www.ensembl.org/id/ENSBTAT00000111936.1" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000096984.1", "url": "https://www.ensembl.org/id/ENSBTAP00000096984.1" } ] } }, { "isoform_ac": "A0AAA9TGU9-1", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TGU9/entry", "sequence": { "sequence": "MAAPICLLERDPSGGCVPDFLPQAQDSNHFIMESLFCESSGDSSLEKEFLGAPVGPSVSTPNSQHSSPSRSLSANSIKVEMYSDEESSRLLGPDERLLEKDDSVIVEDSLSEPLGYCDGSGPEPHSPGGIRLPNGKLKCDVCGMVCIGPNVLMVHKRSHTGERPFHCNQCGASFTQKGNLLRHIKLHSGEKPFKCPFCNYACRRRDALTGHLRTHSVSSPTVGKPYKCNYCGRSYKQQSTLEEHKERCHNYLQSLSTEAQALAGQSGDEIRDLEMVPDSMLHSSSERPTFIDRLANSLTKRKRSTPQKFVGEKQMRFSLSDLPYDVNSGGYEKDVELVAHHGLEPGFGGSLAFVGAEHLRPLRLPPTNCISELTPVISSVYTQMQPLPGRLELPGSREAGEGPEDLADGGPLLYRARGPLTDPGASPSNGCQDSTDTESNHEDRVGGVVSLPQGPPPQPPPAVVVGRPSPAYAKEDPKPQEGLLRGTPGPSKEVLRVVGESGEPVKAFKCEHCRILFLDHVMFTIHMGCHGFRDPFECNICGYHSQDRYEFSSHIVRGEHKVG", "length": 563, "header": "tr|A0AAA9TGU9-1|F1N670_BOVIN Computationally mapped isoform of IKAROS family zinc finger 4 OS=Bos taurus OX=9913 GN=IKZF4 PE=3 SV=1 CANONICAL=F1N670-1" }, "locus": { "chromosome": "5", "start_pos": 57305836, "end_pos": 57292531, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000088143.1", "url": "https://www.ensembl.org/id/ENSBTAT00000088143.1" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000096092.1", "url": "https://www.ensembl.org/id/ENSBTAP00000096092.1" } ] } }, { "isoform_ac": "A0AAA9TKI2-1", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TKI2/entry", "sequence": { "sequence": "MDIEDCNGRSYMSGSGDSSLEKEFLGAPVGPSVSTPNSQHSSPSRSLSANSIKVEMYSDEESSRLLGPDERLLEKDDSVIVEDSLSEPLGYCDGSGPEPHSPGGIRLPNGKLKCDVCGMVCIGPNVLMVHKRSHTGERPFHCNQCGASFTQKGNLLRHIKLHSGEKPFKCPFCNYACRRRDALTGHLRTHSVSSPTVGKPYKCNYCGRSYKQQSTLEEHKERCHNYLQSLSTEAQALAGQSGDEIRDLEMVPDSMLHSSSERPTFIDRLANSLTKRKRSTPQKFVGEKQMRFSLSDLPYDVNSGGYEKDVELVAHHGLEPGFGGSLAFVGAEHLRPLRLPPTNCISELTPVISSVYTQMQPLPGRLELPGSREAGEGPEDLADGGPLLYRARGPLTDPGASPSNGCQDSTDTESNHEDRVGGVVSLPQGPPPQPPPAVVVGRPSPAYAKEDPKPQEGLLRGTPGPSKEVLRVVGESGEPVKAFKCEHCRILFLDHVMFTIHMGCHGFRDPFECNICGYHSQDRYEFSSHIVRGEHKVG", "length": 538, "header": "tr|A0AAA9TKI2-1|F1N670_BOVIN Computationally mapped isoform of IKAROS family zinc finger 4 OS=Bos taurus OX=9913 GN=IKZF4 PE=3 SV=1 CANONICAL=F1N670-1" }, "locus": { "chromosome": "5", "start_pos": 57305855, "end_pos": 57292531, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000100631.1", "url": "https://www.ensembl.org/id/ENSBTAT00000100631.1" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000096775.1", "url": "https://www.ensembl.org/id/ENSBTAP00000096775.1" } ] } }, { "isoform_ac": "F1N670-1", "url": "https://www.uniprot.org/uniprotkb/F1N670/entry", "sequence": { "sequence": "MHTPPALARRFQGGGRARTPGSQRQGKDNLERDPSGGCVPDFLPQAQDSNHFIMESLFCESSGDSSLEKEFLGAPVGPSVSTPNSQHSSPSRSLSANSIKVEMYSDEESSRLLGPDERLLEKDDSVIVEDSLSEPLGYCDGSGPEPHSPGGIRLPNGKLKCDVCGMVCIGPNVLMVHKRSHTGERPFHCNQCGASFTQKGNLLRHIKLHSGEKPFKCPFCNYACRRRDALTGHLRTHSVSSPTVGKPYKCNYCGRSYKQQSTLEEHKERCHNYLQSLSTEAQALAGQSGDEIRDLEMVPDSMLHSSSERPTFIDRLANSLTKRKRSTPQKFVGEKQMRFSLSDLPYDVNSGGYEKDVELVAHHGLEPGFGGSLAFVGAEHLRPLRLPPTNCISELTPVISSVYTQMQPLPGRLELPGSREAGEGPEDLADGGPLLYRARGPLTDPGASPSNGCQDSTDTESNHEDRVGGVVSLPQGPPPQPPPAVVVGRPSPAYAKEDPKPQEGLLRGTPGPSKEVLRVVGESGEPVKAFKCEHCRILFLDHVMFTIHMGCHGFRDPFECNICGYHSQDRYEFSSHIVRGEHKVG", "length": 585, "header": "tr|F1N670-1|F1N670_BOVIN Isoform 1 of IKAROS family zinc finger 4 OS=Bos taurus OX=9913 GN=IKZF4 PE=3 SV=2 CANONICAL=F1N670-1" }, "locus": { "chromosome": "5", "start_pos": 57302803, "end_pos": 57292531, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000038192.5", "url": "https://www.ensembl.org/id/ENSBTAT00000038192.5" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000038008.3", "url": "https://www.ensembl.org/id/ENSBTAP00000038008.3" } ] } } ], "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "other", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 243, "start_aa": "Thr", "end_pos": 243, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr243", "evidence": [ { "id": "", "database": "GlyGen", "url": "https://data.glygen.org/" } ], "filter_code": "000000000000000010000.00000000001000.0.01000" } ], "phosphorylation": [], "glycation": [], "keywords": [ "glycoprotein", "glycoprotein_predicted" ], "publication": [], "pathway": [ { "id": "bta:540671", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?bta:540671", "resource": "KEGG Pathway" } ], "orthologs": [ { "uniprot_canonical_ac": "A0A481C655-1", "protein_name": "IKAROS family zinc finger 4", "gene_name": "IKZF4", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MHTPPALPRRFQGGGRIRTPGSHRQGKDNLERDPSGGCVPDFLPQAQDSNHFIMESLFCESSGDSSLEKEFLGAPVGPSVSTPNSQHSSPSRSLSANSIKVEMYSDEESSRLLGPDERLLEKDDSVIVEDSLSEPLGYCDGSGPEPHSPGGIRLPNGKLKCDVCGMVCIGPNVLMVHKRSHTGERPFHCNQCGASFTQKGNLLRHIKLHSGEKPFKCPFCNYACRRRDALTGHLRTHSVSSPTVGKPYKCNYCGRSYKQQSTLEEHKERCHNYLQSLSTEAQALAGQSGDEIRDLEMVPDSMLHSSSERPTFIDRLANSLTKRKRSTPQKFVGEKQMRFSLSDLPYDVNSGGYEKDVELVAHHGLEPGFGGSLAFVGAEHLRPLRLPPTNCISELTPVISSVYTQMQPLPGRLELPGSREAGEGPEDLADGGPLLYRARGPLTDPGASPSNGCQDSTDTESNHEDRVGGVVSLPQGPPPQPPPTLVVGRPSPAYAKEDPKPQEGLLRGTPGPSKEVLRVVGESGEPVKAFKCEHCRILFLDHVMFTIHMGCHGFRDPFECNICGYHSQDRYEFSSHIVRGEHKVG", "length": 585 }, "evidence": [ { "id": "F1N670", "url": "https://omabrowser.org/oma/group/F1N670/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "A0A8I6AS15-1", "protein_name": "IKAROS family zinc finger 4", "gene_name": "Ikzf4", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MHTPPALPRRFQGGGRVRTPGSHRQGKDNLERELSGGCAPDFLPQAQDSNHFIMESLFCESSGDSSLEKEFLGAPVGPSVSTPNSQHSSPSRSLSANSIKVEMYSDEESSRLLGPDERLLDKDDSVIVEDSLSEPLGYCDGSGPEPHSPGGIRLPNGKLKCDVCGMVCIGPNVLMVHKRSHTGERPFHCNQCGASFTQKGNLLRHIKLHSGEKPFKCPFCNYACRRRDALTGHLRTHSVSSPTVGKPYKCNYCGRSYKQQSTLEEHKERCHNYLQSLSTDAQTLAGQPGDEIRDLEMVPDSMLHPSTERPTFIDRLANSLTKRKRSTPQKFVGEKQMRFSLSDLPYDVNPSGGYEKDVELVAHHGLEPGFGGSLAFVGTEHLRPLRLPPTNCISELTPVISSVYTQMQPLPSRLELPGSREAGEGPEDLGDGGPLLYRARGSLTDPGASPSNGCQDSTDTESNHEDRIGGVVSLPQGPPPQPPPTIVVGRHSPAYAKEDPKPQEGLLRGTPGPSKEVLRVVGESGEPVKAFKCEHCRILFLDHVMFTIHMGCHGFRDPFECNICGYHSQDRYEFSSHIVRGEHKVG", "length": 586 }, "evidence": [ { "id": "F1N670", "url": "https://omabrowser.org/oma/group/F1N670/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "A0A8M3AMX3-1", "protein_name": "Zinc finger protein Eos isoform X1", "gene_name": "ikzf4", "tax_id": 7955, "organism": "Danio rerio", "sequence": { "sequence": "MMNADDCNGRSYMSGSGDSSTEREFFAGLRGPTVSTPNSQQSSPSRSLSANSIKVELYSDEEAGGAPLVERRVGEKDEGWKDEKGDLAEDGGVEMVGGTRGQAGSGCGEMASSEPASPGPIRLPNGKLKCDICGMICIGPNVLMVHKRSHTVLVSVGERPFQCNQCGASFTQKGNLLRHIKLHSGEKPFKCPFCNYACRRRDALTGHLRTHSVSSPTVGKPYKCSYCGRSYKQQSTLEEHRERCHSYLQSLDHQPAHNTQPTHGEESHNVEMISEPLIQSSSEKMTFIDRLANSITKRKRSTPQKFLGEKHMRLNISEAPYDLDPNPDKEGDLLLSHPEGDPAALAEMGGRFMRGPRGGSNDVDPSRSLRMPPHSACLSEFTPVISSVYPHITPLGQRLNCAGGISMGLAGREAGEGHEDLPSTRSRAASPSNGYQDSTDTESMAEEQCVITSAPPGNLNHRGRDRHSPSHAKEMDIEGDREKGVPGGLPTKASPRSPLTREAMQVVDGEGRPVRSFRCEHCRIFFLDHVMFTIHMGCHGFRQPFECNICGHRSQDRYEFSSHIVRGEHQVG", "length": 572 }, "evidence": [ { "id": "F1N670", "url": "https://omabrowser.org/oma/group/F1N670/", "database": "OMA" } ], "glygen_name": "Zebrafish", "common_name": "Zebrafish" }, { "uniprot_canonical_ac": "Q8C208-1", "protein_name": "Zinc finger protein Eos", "gene_name": "Ikzf4", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MHTPPALPRRFQGGGRVRTPGSHRQGKDNLERELSGGCAPDFLPQAQDSNHFIMESLFCESSGDSSLEKEFLGAPVGPSVSTPNSQHSSPSRSLSANSIKVEMYSDEESSRLLGPDERLLDKDDSVIVEDSLSEPLGYCDGSGPEPHSPGGIRLPNGKLKCDVCGMVCIGPNVLMVHKRSHTGERPFHCNQCGASFTQKGNLLRHIKLHSGEKPFKCPFCNYACRRRDALTGHLRTHSVSSPTVGKPYKCNYCGRSYKQQSTLEEHKERCHNYLQSLSTDAQALTGQPGDEIRDLEMVPDSMLHPSTERPTFIDRLANSLTKRKRSTPQKFVGEKQMRFSLSDLPYDVNASGGYEKDVELVAHHGLEPGFGGSLAFVGTEHLRPLRLPPTNCISELTPVISSVYTQMQPIPSRLELPGSREAGEGPEDLGDGGPLLYRARGSLTDPGASPSNGCQDSTDTESNHEDRIGGVVSLPQGPPPQPPPTIVVGRHSPAYAKEDPKPQEGLLRGTPGPSKEVLRVVGESGEPVKAFKCEHCRILFLDHVMFTIHMGCHGFRDPFECNICGYHSQDRYEFSSHIVRGEHKVG", "length": 586 }, "evidence": [ { "id": "F1N670", "url": "https://omabrowser.org/oma/group/F1N670/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q9H2S9-1", "protein_name": "Zinc finger protein Eos", "gene_name": "IKZF4", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MHTPPALPRRFQGGGRVRTPGSHRQGKDNLERDPSGGCVPDFLPQAQDSNHFIMESLFCESSGDSSLEKEFLGAPVGPSVSTPNSQHSSPSRSLSANSIKVEMYSDEESSRLLGPDERLLEKDDSVIVEDSLSEPLGYCDGSGPEPHSPGGIRLPNGKLKCDVCGMVCIGPNVLMVHKRSHTGERPFHCNQCGASFTQKGNLLRHIKLHSGEKPFKCPFCNYACRRRDALTGHLRTHSVSSPTVGKPYKCNYCGRSYKQQSTLEEHKERCHNYLQSLSTEAQALAGQPGDEIRDLEMVPDSMLHSSSERPTFIDRLANSLTKRKRSTPQKFVGEKQMRFSLSDLPYDVNSGGYEKDVELVAHHSLEPGFGSSLAFVGAEHLRPLRLPPTNCISELTPVISSVYTQMQPLPGRLELPGSREAGEGPEDLADGGPLLYRPRGPLTDPGASPSNGCQDSTDTESNHEDRVAGVVSLPQGPPPQPPPTIVVGRHSPAYAKEDPKPQEGLLRGTPGPSKEVLRVVGESGEPVKAFKCEHCRILFLDHVMFTIHMGCHGFRDPFECNICGYHSQDRYEFSSHIVRGEHKVG", "length": 585 }, "evidence": [ { "id": "F1N670", "url": "https://omabrowser.org/oma/group/F1N670/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" } ], "go_annotation": { "categories": [ { "name": "Molecular Function", "total": 7, "go_terms": [ { "name": "DNA binding", "id": "GO:0003677", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003677", "evidence": [ { "database": "UniProtKB", "id": "F1N670", "url": "https://www.uniprot.org/uniprotkb/F1N670" } ], "pmid": "" }, { "name": "zinc ion binding", "id": "GO:0008270", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008270", "evidence": [ { "database": "UniProtKB", "id": "F1N670", "url": "https://www.uniprot.org/uniprotkb/F1N670" } ], "pmid": "" }, { "name": "protein domain specific binding", "id": "GO:0019904", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0019904", "evidence": [ { "database": "UniProtKB", "id": "F1N670", "url": "https://www.uniprot.org/uniprotkb/F1N670" } ], "pmid": "" }, { "name": "sequence-specific DNA binding", "id": "GO:0043565", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0043565", "evidence": [ { "database": "UniProtKB", "id": "F1N670", "url": "https://www.uniprot.org/uniprotkb/F1N670" } ], "pmid": "" }, { "name": "bHLH transcription factor binding", "id": "GO:0043425", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0043425", "evidence": [ { "database": "UniProtKB", "id": "F1N670", "url": "https://www.uniprot.org/uniprotkb/F1N670" } ], "pmid": "" }, { "name": "DNA-binding transcription factor activity", "id": "GO:0003700", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003700", "evidence": [ { "database": "UniProtKB", "id": "F1N670", "url": "https://www.uniprot.org/uniprotkb/F1N670" } ], "pmid": "" }, { "name": "RNA polymerase II cis-regulatory region sequence-specific DNA binding", "id": "GO:0000978", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000978", "evidence": [ { "database": "UniProtKB", "id": "F1N670", "url": "https://www.uniprot.org/uniprotkb/F1N670" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 3, "go_terms": [ { "name": "nucleus", "id": "GO:0005634", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005634", "evidence": [ { "database": "UniProtKB", "id": "F1N670", "url": "https://www.uniprot.org/uniprotkb/F1N670" } ], "pmid": "" }, { "name": "nuclear body", "id": "GO:0016604", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016604", "evidence": [ { "database": "UniProtKB", "id": "F1N670", "url": "https://www.uniprot.org/uniprotkb/F1N670" } ], "pmid": "" }, { "name": "protein-containing complex", "id": "GO:0032991", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0032991", "evidence": [ { "database": "UniProtKB", "id": "F1N670", "url": "https://www.uniprot.org/uniprotkb/F1N670" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 4, "go_terms": [ { "name": "DNA-templated transcription", "id": "GO:0006351", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006351", "evidence": [ { "database": "UniProtKB", "id": "F1N670", "url": "https://www.uniprot.org/uniprotkb/F1N670" } ], "pmid": "" }, { "name": "regulation of DNA-templated transcription", "id": "GO:0006355", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006355", "evidence": [ { "database": "UniProtKB", "id": "F1N670", "url": "https://www.uniprot.org/uniprotkb/F1N670" } ], "pmid": "" }, { "name": "protein homooligomerization", "id": "GO:0051260", "url": 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"total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ], "tool_support": { "graph_view": "yes" } }, { "uniprot_canonical_ac": "F1N6K5-1", "uniprot_ac": "F1N6K5", "uniprot_id": "F1N6K5_BOVIN", "mass": { "chemical_mass": 43771.0, "monoisotopic_mass": 43771.0 }, "refseq": { "ac": "XP_024847449", "name": "haloacid dehalogenase-like hydrolase domain-containing 5 isoform X1", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_024847449" }, "gene_names": [ { "name": "HDHD5", "type": "recommended", "evidence": [ { "id": "F1N6K5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1N6K5" } ] }, { "name": "CECR5", "type": "synonym", "evidence": [ { "id": "XP_024847449", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_024847449" } ] }, { "name": "HDHD5", "type": "synonym", "evidence": [ { "id": "XP_024847449", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_024847449" } ] } ], "protein_names": [ { "name": "Haloacid dehalogenase-like hydrolase domain-containing 5", "type": "recommended", "evidence": [ { "id": "F1N6K5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1N6K5/entry#names_and_taxonomy" } ] }, { "name": "haloacid dehalogenase-like hydrolase domain-containing 5 isoform X1", "type": "synonym", "evidence": [ { "id": "XP_024847449", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_024847449" } ] } ], "function": [], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Bos taurus", "taxid": 9913, "evidence": [ { "database": "UniProtKB", "id": "F1N6K5", "url": "https://www.uniprot.org/uniprotkb/F1N6K5" } ], "common_name": "Bovine", "glygen_name": "Bovine", "reference_species": "Bos taurus [9913]" } ], "gene": [ { "name": "HDHD5", "url": "https://www.uniprot.org/uniprotkb/F1N6K5", "locus": { "chromosome": "5", "start_pos": 108838777, "end_pos": 108849968, "strand": "+", "evidence": [ { "database": "Ensembl Gene", "id": "ENSBTAG00000016995", "url": "https://www.ensembl.org/id/ENSBTAG00000016995" } ] } } ], "crossref": [ { "id": "F1N6K5", "url": "https://alphafold.ebi.ac.uk/entry/F1N6K5", "database": "AlphaFoldDB", "categories": [] }, { "id": "ENSBTAG00000016995", "url": "https://bgee.org/?page=gene&gene_id=ENSBTAG00000016995", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "cd07511", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd07511", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "514441", "url": "https://www.ncbi.nlm.nih.gov/gene/514441", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR006353", "url": "https://www.ebi.ac.uk/interpro/entry/IPR006353", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR006357", "url": "https://www.ebi.ac.uk/interpro/entry/IPR006357", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR023214", "url": "https://www.ebi.ac.uk/interpro/entry/IPR023214", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR036412", "url": "https://www.ebi.ac.uk/interpro/entry/IPR036412", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR050324", "url": "https://www.ebi.ac.uk/interpro/entry/IPR050324", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "HDKRMLV", "url": "https://omabrowser.org/oma/group/HDKRMLV/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "F1N6K5", "url": "https://www.orthodb.org/?gene=F1N6K5", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR14269", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR14269", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR14269:SF17", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR14269:SF17", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF13344", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF13344", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "XP_024847449", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_024847449", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0AAA9SPU0", "url": "https://www.uniprot.org/uniprotkb/A0AAA9SPU0", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0AAA9SPU0-1", "url": "https://www.uniprot.org/uniprotkb/A0AAA9SPU0-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "F1N6K5", "url": "https://www.uniprot.org/uniprotkb/F1N6K5", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "F1N6K5-1", "url": "https://www.uniprot.org/uniprotkb/F1N6K5-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MAALGEAAARWAPGLWRRAVRTAAWLRGRRFASGGTQSPPTFGLLLDIDGVLVRGHQVIPAAQEAFRRLLDPQGQLRVPVVFVTNAGNISQCSKAEELSAQLGFQVEPDQVILSHSPMKLFSQHHDRRMLVSGQGPLVENARALGFKHLVTVDELRAAFPVLDMVDLQRRPKTTLLPRSDFPAIEGVLLLGEPVRWETSLQLITDVLLSDGNPGTGLATAPYPHLPVLASNTDLLWMAEAKMPRFGHGTFLLCLEAIYRKLTGRELCYSGLTGKPSLLTYRYAEGLLARQAARRGWAAPIRSLYAVGDNPMSDIYGANLFHQHLQTQQEGAARSCASILVCTGVYGPQAPSPTVPALGSEGSPFHGHRDFGFRPELLQAAHVVSDLHEAVQLVLRKEGWAL", "length": 401, "header": "tr|F1N6K5-1|F1N6K5_BOVIN Isoform 1 of Haloacid dehalogenase-like hydrolase domain-containing 5 OS=Bos taurus OX=9913 GN=HDHD5 PE=3 SV=1 CANONICAL=F1N6K5-1" }, "isoforms": [ { "isoform_ac": "A0AAA9SPU0-1", "url": "https://www.uniprot.org/uniprotkb/A0AAA9SPU0/entry", "sequence": { "sequence": "MRPPPTPPHPATSLPDLGRSRLLSVQSPPTFGLLLDIDGVLVRGHQVIPAAQEAFRRLLDPQGQLRVPVVFVTNAGNISQCSKAEELSAQLGFQVEPDQVILSHSPMKLFSQHHDRRMLVSGQGPLVENARALGFKHLVTVDELRAAFPVLDMVDLQRRPKTTLLPRSDFPAIEGVLLLGEPVRWETSLQLITDVLLSDGNPGTGLATAPYPHLPVLASNTDLLWMAEAKMPRFGHGTFLLCLEAIYRKLTGRELCYSGLTGKPSLLTYRYAEGLLARQAARRGWAAPIRSLYAVGDNPMSDIYGANLFHQHLQTQQEGAARSCASILVCTGVYGPQAPSPTVPALGSEGSPFHGHRDFGFRPELLQAAHVVSDLHEAVQLVLRKEGWAL", "length": 390, "header": "tr|A0AAA9SPU0-1|F1N6K5_BOVIN Computationally mapped isoform of Haloacid dehalogenase-like hydrolase domain-containing 5 OS=Bos taurus OX=9913 GN=HDHD5 PE=3 SV=1 CANONICAL=F1N6K5-1" }, "locus": { "chromosome": "5", "start_pos": 108846417, "end_pos": 108838993, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000121564.1", "url": "https://www.ensembl.org/id/ENSBTAT00000121564.1" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000088312.1", "url": "https://www.ensembl.org/id/ENSBTAP00000088312.1" } ] } }, { "isoform_ac": "F1N6K5-1", "url": "https://www.uniprot.org/uniprotkb/F1N6K5/entry", "sequence": { "sequence": "MAALGEAAARWAPGLWRRAVRTAAWLRGRRFASGGTQSPPTFGLLLDIDGVLVRGHQVIPAAQEAFRRLLDPQGQLRVPVVFVTNAGNISQCSKAEELSAQLGFQVEPDQVILSHSPMKLFSQHHDRRMLVSGQGPLVENARALGFKHLVTVDELRAAFPVLDMVDLQRRPKTTLLPRSDFPAIEGVLLLGEPVRWETSLQLITDVLLSDGNPGTGLATAPYPHLPVLASNTDLLWMAEAKMPRFGHGTFLLCLEAIYRKLTGRELCYSGLTGKPSLLTYRYAEGLLARQAARRGWAAPIRSLYAVGDNPMSDIYGANLFHQHLQTQQEGAARSCASILVCTGVYGPQAPSPTVPALGSEGSPFHGHRDFGFRPELLQAAHVVSDLHEAVQLVLRKEGWAL", "length": 401, "header": "tr|F1N6K5-1|F1N6K5_BOVIN Isoform 1 of Haloacid dehalogenase-like hydrolase domain-containing 5 OS=Bos taurus OX=9913 GN=HDHD5 PE=3 SV=1 CANONICAL=F1N6K5-1" }, "locus": { "chromosome": "5", "start_pos": 108849947, "end_pos": 108838993, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000042747.4", "url": "https://www.ensembl.org/id/ENSBTAT00000042747.4" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000040374.2", "url": "https://www.ensembl.org/id/ENSBTAP00000040374.2" } ] } } ], "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "other", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 353, "start_aa": "Thr", "end_pos": 353, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr353", "evidence": [ { "id": "", "database": "GlyGen", "url": "https://data.glygen.org/" } ], "filter_code": "000000000000000010000.00000000001000.0.01000" } ], "phosphorylation": [], "glycation": [], "keywords": [ "glycoprotein", "glycoprotein_predicted" ], "publication": [], "pathway": [], "orthologs": [ { "uniprot_canonical_ac": "A0A0R4IJ50-1", "protein_name": "Haloacid dehalogenase-like hydrolase domain-containing 5", "gene_name": "hdhd5", "tax_id": 7955, "organism": "Danio rerio", "sequence": { "sequence": "MAQMFSRLNMLGIGWRGVRFSRKVTNAAVSAQTQRRYSTDVDEQNRHLFGLLFDIDGVLVRGRTPIPAAKQCFRNLVDGDGKYKVPVVFVTNAGNALRQTKAEQLSHLLEVEVSPEQVVLSHSPLRVFTQFHDMCVLVSGQGPVVEVAHNVGFKNVVTIDMLREAYPLLDVVDHHRRPKDTIPQTKDLPHIDAVILFGEPIRWETNLQLIVDVLLTNGRPGNPVTSLHYPHIPVLACNMDLLWMAEAKNPRFGHGMFLVCLESIYKKITGCELKYEALIGKPSVVTYNYAELLIREQAEKLGWTRPVQRLYAIGDNPMADIYGANLYNRYLKAMNRSRTPQVQAQGGVSGQMAADLHCDDAKCSGQVMVGGSFEHCLPEACSSILVCTGVYNRDMPTDPQETLTEHRIFHGHRDFRFDPSLTQPSFIVNDVRDGVELVFQLEGWPLE", "length": 447 }, "evidence": [ { "id": "F1N6K5", "url": "https://omabrowser.org/oma/group/F1N6K5/", "database": "OMA" } ], "glygen_name": "Zebrafish", "common_name": "Zebrafish" }, { "uniprot_canonical_ac": "A0A8V0YEP4-1", "protein_name": "Haloacid dehalogenase-like hydrolase domain-containing 5", "gene_name": "HDHD5", "tax_id": 9031, "organism": "Gallus gallus", "sequence": { "sequence": "MNDIDSGTECTFSMFTDDTKLRGAVNVLQGWDAVQRDQDRLEQWAQPPAFGFLFDIDGVLVRGSQVVPAAREAFRRLSDAGGRLRVPVVFLTNAGNCLRAAKARELSQALGLQVSPEQVILSHSPLRLFSQFHPKCVLVAGQGPVEENARNLGFKHVVTIEALRKAYPLLDMVDQSRRPKELPPPTTGFPTIEGVVLFGEPVRWETSLQLIIDVLLSNGNPGAEPEGIPYPHLPVLACNMDLLWMAEAKMPRFGHGTFLLCLENIYKKVTGRELKYEALIGKPSTVTYRYAEYLIKEQAEKHGWKAPIRRLYAIGDNPMSDVYGANLYNNYLKSAQQNQVEAGVKRIPQAANPQTEDRLAVESCESILVCTGVYRHNADVSRKPEECNMETVFHGHRDFCFDPSLVEASYIVQDVNEAVLLAFEKENWS", "length": 429 }, "evidence": [ { "id": "F1N6K5", "url": "https://omabrowser.org/oma/group/F1N6K5/", "database": "OMA" } ], "glygen_name": "Chicken", "common_name": "Chicken" }, { "uniprot_canonical_ac": "D3ZQB6-1", "protein_name": "Haloacid dehalogenase-like hydrolase domain-containing 5", "gene_name": "Hdhd5", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MVGLPPPRGSARAAADWLLGCARGGGSRVGETRSLRVRATSAMAALARLGVLGPGRCLWKLPVRLSAEFQGYGPRRGYVADRAERSPTFGLLFDIDGVLVRGHRVIPAALEAFSKLVNSQGQLQVPVVFVTNAGNILQRDKAQELSALLECKVDPDQVILSHSPMKLFLQYHNKRMLVSGQGPLVENARALGFQNVVTVDDLRIAFPELDMVDLQRRPKTMRPRSDFPAIEGVLLLGEPVRWETNLQLITDVLLSNGHPGAGLATAPYPHLPVLASNMDLLWMAEASMPRFGHGTFLLCLETIYRKITGHELKYEGLMGKPSILTYRYAEEVIRQQAERRGWAAPIRKLYAIGTCKWQMVERRSNGLMDKRSSGLQQPGAVLPSWCALVYTVLRTQAPKHLLLEGQSSHSTGTETSASVQSS", "length": 422 }, "evidence": [ { "id": "F1N6K5", "url": "https://omabrowser.org/oma/group/F1N6K5/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "F1SHR6-1", "protein_name": "Haloacid dehalogenase-like hydrolase domain-containing 5", "gene_name": "HDHD5", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MIGRAAGRACAVRAGGGPWLRSARWWRGGRPGCGGGRLAGRRAGPRGRRAGGQGRRGPSCLPSVQRPPTFGFLLDIDGVLVRGHRIIPAAQEAFHKLLNPEGQLRVPVVFVTNAGNILQHGKAQELSALLGFQVEPDQVILSHSPMRLFSQHHERRMLVSGQGPLVENARALGFKSLVTVDELRAAFPVLDMVDLQRRPKTTVIWASSWVLLLGEPVRWETSLQLIMDVLLSDGNPGTGLATAPYPHLPVLAMAGCFSGRFGHGTFLLCLEAIYRKVTGKELRYEGLMGKPSLLTYQYAEGLLRRQAERRGWAAPIRNLYAVGDNPMSDIYGANLFHQYLQTARSVGAEEGARGPWKQQPSTARSCTSILVCTGVYSPEAPESPGPGLLEAAHVVSDVHEAVQLVLRKEGWAL", "length": 413 }, "evidence": [ { "id": "F1N6K5", "url": "https://omabrowser.org/oma/group/F1N6K5/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "Q54QC3-1", "protein_name": "Uncharacterized protein", "gene_name": "", "tax_id": 44689, "organism": "Dictyostelium discoideum", "sequence": { "sequence": "MAIDKTETTTATTTTTTTTTTTTTNDSSFGIVFDIDGVLMRDGVIIPNATQALKLLEDKETSEPKIPYIFMTNNGGFTEEEKANKISKVLQYNIPSDKVMVAHTPVRPLAEKYKDYDVLLISKTHETSKKLADWYGFKNYKSLQQYIEERPFLCPSKYSTFWTQGVSSEYVIKEAKKQLPIKAIILLEDPIDWGECIQIVSDILQSKDGLLRKDYINRADVQSIDFHICNPDFSYAGEFVIPRYTMGAILECIKLLFKTQTGRDLIYTLYGKPYPLTYQYGKQIISNQISKLGFNDGCILKHIYAIGDNPYSDIKGANNLEHEGWISILVKTGCFKGDTNHPEIPAKYVVDNVYDAVKLILKLEGQ", "length": 366 }, "evidence": [ { "id": "F1N6K5", "url": "https://omabrowser.org/oma/group/F1N6K5/", "database": "OMA" } ], "glygen_name": "Cellular slime mold", "common_name": "Social amoeba" }, { "uniprot_canonical_ac": "Q91WM2-1", "protein_name": "Haloacid dehalogenase-like hydrolase domain-containing 5", "gene_name": "Hdhd5", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MAALAGLGVLGAGRHLWKLPVRLSAGLQGCGPRRGYIAGSAERSPTFGLLFDIDGVLVRGHRVIPAALEAFSKLVNSQGQLRVPVVFVTNAGNILQHNKAQELSDLLRCKVDPDQVILSHSPMKLFLQYHSKQMLVSGQGPLVENARALGFQNVVTIDELRLAFPELDMVDLQRRPKTMRLRSDFPAIEGVLLLGEPVRWETNLQLIMDVLLSNGHPGTGLATAPYPHLPVLASNMDLLWMAEAKMPRFGHGTFLLCLETIYRKITGNELKYEGLMGKPSILTYQYAEDVIRQQAERRGWAAPIRKLYAIGDNPMSDVYGANLFHQYLQMANRGEEEQQTGGQQKQRPSATQSCASILVCTGIYSSQDPGSQVPPPGRRELPFHGHRDFSFSPGLLEASHIVHDVNEAVQLVFHQEGWA", "length": 419 }, "evidence": [ { "id": "F1N6K5", "url": "https://omabrowser.org/oma/group/F1N6K5/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q9BXW7-1", "protein_name": "Haloacid dehalogenase-like hydrolase domain-containing 5", "gene_name": "HDHD5", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MAAWGCVAALGAARGLCWRAARAAAGLQGRPARRCYAVGPAQSPPTFGFLLDIDGVLVRGHRVIPAALKAFRRLVNSQGQLRVPVVFVTNAGNILQHSKAQELSALLGCEVDADQVILSHSPMKLFSEYHEKRMLVSGQGPVMENAQGLGFRNVVTVDELRMAFPLLDMVDLERRLKTTPLPRNDFPRIEGVLLLGEPVRWETSLQLIMDVLLSNGSPGAGLATPPYPHLPVLASNMDLLWMAEAKMPRFGHGTFLLCLETIYQKVTGKELRYEGLMGKPSILTYQYAEDLIRRQAERRGWAAPIRKLYAVGDNPMSDVYGANLFHQYLQKATHDGAPELGAGGTRQQQPSASQSCISILVCTGVYNPRNPQSTEPVLGGGEPPFHGHRDLCFSPGLMEASHVVNDVNEAVQLVFRKEGWALE", "length": 423 }, "evidence": [ { "id": "F1N6K5", "url": "https://omabrowser.org/oma/group/F1N6K5/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "Q9M169-1", "protein_name": "Hydrolase family protein / HAD-superfamily protein", "gene_name": "", "tax_id": 3702, "organism": "Arabidopsis thaliana", "sequence": { "sequence": "MNHLLILARNSLRRRNFNLRPPSRSFSSTISPESNRSSFGIAFDIDGVILLGSSPVGGSPSALRRLYDDSGALKIPFLFLTNGGGLPESKRASEMSHLLGVQVSPLQVIQAHSPFRKLVNRFENELVVAAGKGEPAAVMSNYGFKNVISMDEYASYFDNIDPLAPYKKLMFRQDGHKELRSREDVLSQRVQAAFIVSDPVDWSRDIQVLCDILRTGGLPGKEIGPQPHLYIANDDLDYQTEFPTERLGMGAFRIALESIFNRIHEKPLEYTSFGKPNPFVFKNAEDVLKEIATSPYSSNQGSHHFKTLYMIGDNPKIDIRGARQAGTPWFSILTRTGVFKGKDNHSEFPADLVVDTVEEAVDFILTRESAKQSLLS", "length": 376 }, "evidence": [ { "id": "F1N6K5", "url": "https://omabrowser.org/oma/group/F1N6K5/", "database": "OMA" } ], "glygen_name": "Arabidopsis", "common_name": "Mouse-ear cress" } ], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 1, "go_terms": [ { "name": "mitochondrion", "id": "GO:0005739", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005739", "evidence": [ { "database": "UniProtKB", "id": "F1N6K5", "url": "https://www.uniprot.org/uniprotkb/F1N6K5" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 1, "go_terms": [ { "name": "glycerophospholipid biosynthetic process", "id": "GO:0046474", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0046474", "evidence": [ { "database": "UniProtKB", "id": "F1N6K5", "url": "https://www.uniprot.org/uniprotkb/F1N6K5" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 88, "end_pos": 90, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [ { "pdb_id": "AF-F1N6K5-F1", "pdb_chain": "global", "start_pos": 1, "end_pos": 401, "overlap": "1.0", "method": "AlphaFold", "type": "alphafold", "resolution": -1.0, "url": "https://data.glygen.org/ln2downloads/pdb/current/AF-F1N6K5-F1.pdb", "url_external": "https://alphafold.ebi.ac.uk/entry/F1N6K5" } ], "lectin_list": [], "domain_list": [], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" }, { "name": 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Has acyl-CoA thioesterase activity towards medium (C12) and long-chain (C18) fatty acyl-CoA substrates. Can also hydrolyze 3-hydroxyphenylacetyl-CoA and 3,4-dihydroxyphenylacetyl-CoA (in vitro). 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"categories": [ "Enzyme and Pathway" ] }, { "id": "A0AAA9SQK3", "url": "https://www.uniprot.org/uniprotkb/A0AAA9SQK3", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0AAA9SQK3-1", "url": "https://www.uniprot.org/uniprotkb/A0AAA9SQK3-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "F6QGE6", "url": "https://www.uniprot.org/uniprotkb/F6QGE6", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "F6QGE6-1", "url": "https://www.uniprot.org/uniprotkb/F6QGE6-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MARAKRHMRALSRRGLNVSDEVLDVSAPAAREGTVVRSAADPERSSGPRRLLTLFFCELQGSPALPRLSLKWGLGAGERSTMIWVKKAKTLLEWLTHSGKFNGFDRNLEKVTLVSAAPGKLICEMKVEEQHANKMGTLHGGMIATLVDVISSLALLCTERGISGVSVDMNITYMSPAKVGEDILITAHVLKEGRSLSFASVDLMNKATGKLIAQGRHTKHMGNRPPEGSVKKSNNE", "length": 236, "header": "tr|F6QGE6-1|F6QGE6_BOVIN Isoform 1 of Acyl-coenzyme A thioesterase 13 OS=Bos taurus OX=9913 GN=ACOT13 PE=3 SV=1 CANONICAL=F6QGE6-1" }, "isoforms": [ { "isoform_ac": "A0AAA9SQK3-1", "url": "https://www.uniprot.org/uniprotkb/A0AAA9SQK3/entry", "sequence": { "sequence": "VVRKVTLVSAAPGKLICEMKVEEQHANKMGTLHGGMIATLVDVISSLALLCTERGISGVSVDMNITYMSPAKVGEDILITAHVLKEGRSLSFASVDLMNKATGKLIAQGRHTKHMGNRPPEGSVKKSNNE", "length": 130, "header": "tr|A0AAA9SQK3-1|F6QGE6_BOVIN Computationally mapped isoform of Acyl-coenzyme A thioesterase 13 OS=Bos taurus OX=9913 GN=ACOT13 PE=3 SV=1 CANONICAL=F6QGE6-1" }, "locus": { "chromosome": "23", "start_pos": 33077367, "end_pos": 33069984, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000128973.1", "url": "https://www.ensembl.org/id/ENSBTAT00000128973.1" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000086309.1", "url": "https://www.ensembl.org/id/ENSBTAP00000086309.1" } ] } }, { "isoform_ac": "F6QGE6-1", "url": "https://www.uniprot.org/uniprotkb/F6QGE6/entry", "sequence": { "sequence": "MARAKRHMRALSRRGLNVSDEVLDVSAPAAREGTVVRSAADPERSSGPRRLLTLFFCELQGSPALPRLSLKWGLGAGERSTMIWVKKAKTLLEWLTHSGKFNGFDRNLEKVTLVSAAPGKLICEMKVEEQHANKMGTLHGGMIATLVDVISSLALLCTERGISGVSVDMNITYMSPAKVGEDILITAHVLKEGRSLSFASVDLMNKATGKLIAQGRHTKHMGNRPPEGSVKKSNNE", "length": 236, "header": "tr|F6QGE6-1|F6QGE6_BOVIN Isoform 1 of Acyl-coenzyme A thioesterase 13 OS=Bos taurus OX=9913 GN=ACOT13 PE=3 SV=1 CANONICAL=F6QGE6-1" }, "locus": { "chromosome": "23", "start_pos": 33082602, "end_pos": 33069984, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000021731.6", "url": "https://www.ensembl.org/id/ENSBTAT00000021731.6" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000021731.5", "url": "https://www.ensembl.org/id/ENSBTAP00000021731.5" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [ "enzyme" ], "publication": [], "pathway": [ { "id": "R-BTA-77289", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-BTA-77289", "resource": "Reactome", "description": "Mitochondrial Fatty Acid Beta-Oxidation" } ], "orthologs": [], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 4, "go_terms": [ { "name": "nucleus", "id": "GO:0005634", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005634", "evidence": [ { "database": "UniProtKB", "id": "F6QGE6", "url": "https://www.uniprot.org/uniprotkb/F6QGE6" } ], "pmid": "" }, { "name": "mitochondrion", "id": "GO:0005739", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005739", "evidence": [ { "database": "UniProtKB", "id": "F6QGE6", "url": "https://www.uniprot.org/uniprotkb/F6QGE6" } ], "pmid": "" }, { "name": "spindle", "id": "GO:0005819", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005819", "evidence": [ { "database": "UniProtKB", "id": "F6QGE6", "url": "https://www.uniprot.org/uniprotkb/F6QGE6" } ], "pmid": "" }, { "name": "cytosol", "id": "GO:0005829", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005829", "evidence": [ { "database": "UniProtKB", "id": "F6QGE6", "url": "https://www.uniprot.org/uniprotkb/F6QGE6" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 1, "go_terms": [ { "name": "lipid metabolic process", "id": "GO:0006629", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006629", "evidence": [ { "database": "UniProtKB", "id": "F6QGE6", "url": "https://www.uniprot.org/uniprotkb/F6QGE6" } ], "pmid": "" } ] }, { "name": "Molecular Function", "total": 1, "go_terms": [ { "name": "fatty acyl-CoA hydrolase activity", "id": "GO:0047617", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0047617", "evidence": [ { "database": "UniProtKB", "id": "F6QGE6", "url": "https://www.uniprot.org/uniprotkb/F6QGE6" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 170, "end_pos": 172, "annotation": "n_glycosylation_sequon" }, { "start_pos": 17, "end_pos": 19, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [ { "id": "16645", "name": "", "equation": "hexadecanoyl-CoA + H2O = hexadecanoate + CoA + H(+)", "summary": "", "cellular_location": "", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [ "A1A4L1-1", "A5PJT0-1", "Q3T0R7-1", "A0ABI0P2S3-1", "Q3SWX2-1", "P45478-1", "F6RWU6-1", "A0A3Q1M171-1", "F6QGE6-1", "Q1JQA0-1", "A0AAA9T509-1", "E1BB89-1", "A0AAA9SCF5-1" ], "evidence": [ { "id": "16645", "database": "Rhea", "url": "https://www.rhea-db.org/rhea/16645" } ] }, { "id": "16781", "name": "", "equation": "a fatty acyl-CoA + H2O = a fatty acid + CoA + H(+)", "summary": "", "cellular_location": "", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [ "F6QGE6-1" ], "evidence": [ { "id": "16781", "database": "Rhea", "url": "https://www.rhea-db.org/rhea/16781" } ] }, { "id": "30135", "name": "", "equation": "dodecanoyl-CoA + H2O = dodecanoate + CoA + H(+)", "summary": "", "cellular_location": "", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [ "A1A4L1-1", "A5PJT0-1", "Q3T0R7-1", "A0ABI0P2S3-1", "F6RWU6-1", "A0A3Q1M171-1", "F6QGE6-1", "A0AAA9T509-1" ], "evidence": [ { "id": "30135", "database": "Rhea", "url": "https://www.rhea-db.org/rhea/30135" } ] }, { "id": "30143", "name": "", "equation": "octanoyl-CoA + H2O = octanoate + CoA + H(+)", "summary": "", "cellular_location": "", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [ "A1A4L1-1", "Q3T0R7-1", "A0ABI0P2S3-1", "Q3SWX2-1", "F6RWU6-1", "F6QGE6-1" ], "evidence": [ { "id": "30143", "database": "Rhea", "url": "https://www.rhea-db.org/rhea/30143" } ] }, { "id": "40059", "name": "", "equation": "decanoyl-CoA + H2O = decanoate + CoA + H(+)", "summary": "", "cellular_location": "", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [ "A1A4L1-1", "Q3T0R7-1", "A0ABI0P2S3-1", "Q3SWX2-1", "F6RWU6-1", "F6QGE6-1", "A0AAA9T509-1" ], "evidence": [ { "id": "40059", "database": "Rhea", "url": "https://www.rhea-db.org/rhea/40059" } ] }, { "id": "40111", "name": "", "equation": "butanoyl-CoA + H2O = butanoate + CoA + H(+)", "summary": "", "cellular_location": "", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [ "A0A3Q1M171-1", "E1BNW7-1", "Q3T0R7-1", "Q3SWX2-1", "F6RWU6-1", "F6QGE6-1" ], "evidence": [ { "id": "40111", "database": "Rhea", "url": "https://www.rhea-db.org/rhea/40111" } ] }, { "id": "40115", "name": "", "equation": "hexanoyl-CoA + H2O = hexanoate + CoA + H(+)", "summary": "", "cellular_location": "", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [ "Q3T0R7-1", "E1BNW7-1", "F6RWU6-1", "F6QGE6-1" ], "evidence": [ { "id": "40115", "database": "Rhea", "url": "https://www.rhea-db.org/rhea/40115" } ] }, { "id": "40119", "name": "", "equation": "tetradecanoyl-CoA + H2O = tetradecanoate + CoA + H(+)", "summary": "", "cellular_location": "", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [ "A1A4L1-1", "A5PJT0-1", "Q3T0R7-1", "A0ABI0P2S3-1", "Q3SWX2-1", "F6RWU6-1", "A0A3Q1M171-1", "F6QGE6-1", "A0AAA9T509-1" ], "evidence": [ { "id": "40119", "database": "Rhea", "url": "https://www.rhea-db.org/rhea/40119" } ] }, { "id": "40139", "name": "", "equation": "(9Z)-octadecenoyl-CoA + H2O = (9Z)-octadecenoate + CoA + H(+)", "summary": "", "cellular_location": "", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [ "A1A4L1-1", "A0ABI0P2S3-1", "F6RWU6-1", "F6QGE6-1" ], "evidence": [ { "id": "40139", "database": "Rhea", "url": "https://www.rhea-db.org/rhea/40139" } ] }, { "id": "R-BTA-5690043", "name": "Cytosolic ACOTs hydrolyse MCFA-CoA, LCFA-CoA", "equation": "", "summary": "This event has been computationally inferred from an event that has been demonstrated in another species.

The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.

More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "cellular_location": "cytosol", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [ "F6QGE6-1", "E1BNW7-1" ], "evidence": [ { "id": "R-BTA-5690043", "database": "Reactome", "url": "https://www.reactome.org/PathwayBrowser/#R-BTA-5690043" } ] } ], "reaction_participants": [], "reaction_enzymes": [ { "uniprot_ac": "A0A3Q1M171", "gene_name": "ACOT11", "activity": [ { "ec_number": "3.1.2.2", "activity": "hexadecanoyl-CoA + H2O = hexadecanoate + CoA + H(+).", "evidence": [ { "id": "A0A3Q1M171", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1M171" } ] }, { "ec_number": "3.1.2.2", "activity": "", "evidence": [ { "id": "A0A3Q1M171", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1M171" } ] } ] }, { "uniprot_ac": "A0AAA9SCF5", "gene_name": "PPT1", "activity": [ { "ec_number": "3.1.2.22", "activity": "S-hexadecanoyl-L-cysteinyl-[protein] + H2O = L-cysteinyl-[protein] + hexadecanoate + H(+).", "evidence": [ { "id": "A0AAA9SCF5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9SCF5" } ] }, { "ec_number": "3.1.2.2", "activity": "hexadecanoyl-CoA + H2O = hexadecanoate + CoA + H(+).", "evidence": [ { "id": "A0AAA9SCF5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9SCF5" } ] }, { "ec_number": "3.1.2.2", "activity": "", "evidence": [ { "id": "A0AAA9SCF5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9SCF5" } ] }, { "ec_number": "3.1.2.22", "activity": "", "evidence": [ { "id": "A0AAA9SCF5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9SCF5" } ] } ] }, { "uniprot_ac": "A0AAA9T509", "gene_name": "OLAH", "activity": [ { "ec_number": "3.1.2.14", "activity": "hexadecanoyl-[ACP] + H2O = hexadecanoate + holo-[ACP] + H(+).", "evidence": [ { "id": "A0AAA9T509", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9T509" } ] }, { "ec_number": "3.1.2.14", "activity": "", "evidence": [ { "id": "A0AAA9T509", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9T509" } ] } ] }, { "uniprot_ac": "A0ABI0P2S3", "gene_name": "THEM4", "activity": [ { "ec_number": "3.1.2.2", "activity": "hexadecanoyl-CoA + H2O = hexadecanoate + CoA + H(+).", "evidence": [ { "id": "A0ABI0P2S3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0ABI0P2S3" } ] }, { "ec_number": "3.1.2.2", "activity": "", "evidence": [ { "id": "A0ABI0P2S3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0ABI0P2S3" } ] } ] }, { "uniprot_ac": "A1A4L1", "gene_name": "THEM4", "activity": [ { "ec_number": "3.1.2.2", "activity": "hexadecanoyl-CoA + H2O = hexadecanoate + CoA + H(+).", "evidence": [ { "id": "A1A4L1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A1A4L1" } ] }, { "ec_number": "3.1.2.2", "activity": "", "evidence": [ { "id": "A1A4L1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A1A4L1" } ] } ] }, { "uniprot_ac": "A5PJT0", "gene_name": "MBLAC2", "activity": [ { "ec_number": "3.1.2.2", "activity": "hexadecanoyl-CoA + H2O = hexadecanoate + CoA + H(+).", "evidence": [ { "id": "A5PJT0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A5PJT0" } ] }, { "ec_number": "3.5.2.6", "activity": "a beta-lactam + H2O = a substituted beta-amino acid.", "evidence": [ { "id": "A5PJT0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A5PJT0" } ] }, { "ec_number": "3.1.2.2", "activity": "", "evidence": [ { "id": "A5PJT0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A5PJT0" } ] } ] }, { "uniprot_ac": "E1BB89", "gene_name": "PLA2G6", "activity": [ { "ec_number": "3.1.2.2", "activity": "hexadecanoyl-CoA + H2O = hexadecanoate + CoA + H(+).", "evidence": [ { "id": "E1BB89", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BB89" } ] }, { "ec_number": "3.1.1.4", "activity": "a 1-O-alkyl-2-acyl-sn-glycero-3-phosphocholine + H2O = a 1-O-alkyl-sn-glycero-3-phosphocholine + a fatty acid + H(+).", "evidence": [ { "id": "E1BB89", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BB89" } ] }, { "ec_number": "3.1.1.5", "activity": "a 1-acyl-sn-glycero-3-phosphocholine + H2O = sn-glycerol 3-phosphocholine + a fatty acid + H(+).", "evidence": [ { "id": "E1BB89", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BB89" } ] }, { "ec_number": "3.1.1.4", "activity": "", "evidence": [ { "id": "E1BB89", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BB89" } ] }, { "ec_number": "3.1.1.5", "activity": "", "evidence": [ { "id": "E1BB89", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BB89" } ] }, { "ec_number": "3.1.2.2", "activity": "", "evidence": [ { "id": "E1BB89", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BB89" } ] } ] }, { "uniprot_ac": "E1BNW7", "gene_name": "ACOT12", "activity": [ { "ec_number": "3.1.2.1", "activity": "acetyl-CoA + H2O = acetate + CoA + H(+).", "evidence": [ { "id": "E1BNW7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BNW7" } ] }, { "ec_number": "3.1.2.1", "activity": "", "evidence": [ { "id": "E1BNW7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BNW7" } ] } ] }, { "uniprot_ac": "F6QGE6", "gene_name": "ACOT13", "activity": [ { "ec_number": "3.1.2.2", "activity": "hexadecanoyl-CoA + H2O = hexadecanoate + CoA + H(+).", "evidence": [ { "id": "F6QGE6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F6QGE6" } ] }, { "ec_number": "3.1.2.2", "activity": "", "evidence": [ { "id": "F6QGE6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F6QGE6" } ] } ] }, { "uniprot_ac": "F6RWU6", "gene_name": "ACOT8", "activity": [ { "ec_number": "3.1.2.2", "activity": "hexadecanoyl-CoA + H2O = hexadecanoate + CoA + H(+).", "evidence": [ { "id": "F6RWU6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F6RWU6" } ] }, { "ec_number": "3.1.2.27", "activity": "(3S)-3-hydroxy-3-methylglutaryl-CoA + H2O = 3-hydroxy-3-methylglutarate + CoA + H(+).", "evidence": [ { "id": "F6RWU6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F6RWU6" } ] }, { "ec_number": "3.1.2.1", "activity": "acetyl-CoA + H2O = acetate + CoA + H(+).", "evidence": [ { "id": "F6RWU6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F6RWU6" } ] }, { "ec_number": "3.1.2.11", "activity": "acetoacetyl-CoA + H2O = acetoacetate + CoA + H(+).", "evidence": [ { "id": "F6RWU6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F6RWU6" } ] }, { "ec_number": "3.1.2.3", "activity": "succinyl-CoA + H2O = succinate + CoA + H(+).", "evidence": [ { "id": "F6RWU6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F6RWU6" } ] }, { "ec_number": "3.1.2.5", "activity": "(3S)-3-hydroxy-3-methylglutaryl-CoA + H2O = 3-hydroxy-3-methylglutarate + CoA + H(+).", "evidence": [ { "id": "F6RWU6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F6RWU6" } ] }, { "ec_number": "3.1.2.11", "activity": "", "evidence": [ { "id": "F6RWU6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F6RWU6" } ] }, { "ec_number": "3.1.2.5", "activity": "", "evidence": [ { "id": "F6RWU6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F6RWU6" } ] }, { "ec_number": "3.1.2.27", "activity": "", "evidence": [ { "id": "F6RWU6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F6RWU6" } ] }, { "ec_number": "3.1.2.2", "activity": "", "evidence": [ { "id": "F6RWU6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F6RWU6" } ] }, { "ec_number": "3.1.2.3", "activity": "", "evidence": [ { "id": "F6RWU6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F6RWU6" } ] }, { "ec_number": "3.1.2.1", "activity": "", "evidence": [ { "id": "F6RWU6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F6RWU6" } ] } ] }, { "uniprot_ac": "P45478", "gene_name": "PPT1", "activity": [ { "ec_number": "3.1.2.22", "activity": "S-hexadecanoyl-L-cysteinyl-[protein] + H2O = L-cysteinyl-[protein] + hexadecanoate + H(+).", "evidence": [ { "id": "P45478", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P45478" } ] }, { "ec_number": "3.1.2.2", "activity": "hexadecanoyl-CoA + H2O = hexadecanoate + CoA + H(+).", "evidence": [ { "id": "P45478", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P45478" } ] }, { "ec_number": "3.1.2.22", "activity": "", "evidence": [ { "id": "P45478", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P45478" } ] }, { "ec_number": "3.1.2.2", "activity": "", "evidence": [ { "id": "P45478", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P45478" } ] } ] }, { "uniprot_ac": "Q1JQA0", "gene_name": "PPT2", "activity": [ { "ec_number": "3.1.2.2", "activity": "hexadecanoyl-CoA + H2O = hexadecanoate + CoA + H(+).", "evidence": [ { "id": "Q1JQA0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q1JQA0" } ] }, { "ec_number": "3.1.2.2", "activity": "", "evidence": [ { "id": "Q1JQA0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q1JQA0" } ] } ] }, { "uniprot_ac": "Q3SWX2", "gene_name": "ACOT9", "activity": [ { "ec_number": "3.1.2.-", "activity": "", "evidence": [ { "id": "Q3SWX2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q3SWX2" } ] }, { "ec_number": "3.1.2.2", "activity": "hexadecanoyl-CoA + H2O = hexadecanoate + CoA + H(+).", "evidence": [ { "id": "Q3SWX2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q3SWX2" } ] }, { "ec_number": "3.1.2.2", "activity": "", "evidence": [ { "id": "Q3SWX2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q3SWX2" } ] } ] }, { "uniprot_ac": "Q3T0R7", "gene_name": "ACAA2", "activity": [ { "ec_number": "3.1.2.-", "activity": "", "evidence": [ { "id": "Q3T0R7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q3T0R7" } ] }, { "ec_number": "3.1.2.2", "activity": "hexadecanoyl-CoA + H2O = hexadecanoate + CoA + H(+).", "evidence": [ { "id": "Q3T0R7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q3T0R7" } ] }, { "ec_number": "3.1.2.1", "activity": "acetyl-CoA + H2O = acetate + CoA + H(+).", "evidence": [ { "id": "Q3T0R7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q3T0R7" } ] }, { "ec_number": "2.3.1.16", "activity": "an acyl-CoA + acetyl-CoA = a 3-oxoacyl-CoA + CoA.", "evidence": [ { "id": "Q3T0R7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q3T0R7" } ] }, { "ec_number": "2.3.1.9", "activity": "2 acetyl-CoA = acetoacetyl-CoA + CoA.", "evidence": [ { "id": "Q3T0R7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q3T0R7" } ] }, { "ec_number": "2.3.1.16", "activity": "", "evidence": [ { "id": "Q3T0R7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q3T0R7" } ] } ] } ], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "F6QGE6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F6QGE6" }, { "id": "PF03061", "database": "Pfam", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF03061" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "Thioesterase", "eco_id": "ECO_0000259", "start_pos": 135, "end_pos": 209, "start_aa": "Met", "end_aa": "Gly", "glycosite_overlap": [] } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [ { "ec_number": "3.1.2.2", "ec_name": "hexadecanoyl-CoA + H2O = hexadecanoate + CoA + H(+).", "evidence": [ { "id": "3.1.2.2", "database": "Rhea", "url": "https://www.rhea-db.org/rhea/?query=ec:3.1.2.2" }, { "id": "3.1.2.2", "database": "BRENDA Enzymes", "url": "https://www.brenda-enzymes.org/enzyme.php?ecno=3.1.2.2" } ] } ], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 170, "end_pos": 172 }, { "start_pos": 17, "end_pos": 19 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": 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"tool_support": { "graph_view": "yes" } }, { "uniprot_canonical_ac": "F1N5A9-1", "uniprot_ac": "F1N5A9", "uniprot_id": "F1N5A9_BOVIN", "mass": { "chemical_mass": 79027.0, "monoisotopic_mass": 79027.0 }, "refseq": {}, "gene_names": [ { "name": "TMEM260", "type": "recommended", "evidence": [ { "id": "F1N5A9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1N5A9" } ] } ], "protein_names": [ { "name": "Transmembrane protein 260", "type": "synonym", "evidence": [ { "id": "F1N5A9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1N5A9/entry#names_and_taxonomy" } ] } ], "function": [], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Bos taurus", "taxid": 9913, "evidence": [ { "database": "UniProtKB", "id": "F1N5A9", "url": "https://www.uniprot.org/uniprotkb/F1N5A9" } ], "common_name": "Bovine", "glygen_name": "Bovine", "reference_species": "Bos taurus [9913]" } ], "gene": [ { "name": "TMEM260", "url": "https://www.uniprot.org/uniprotkb/F1N5A9", "locus": { "chromosome": "10", "start_pos": 69078053, "end_pos": 68996643, "strand": "-", "evidence": [ { "database": "Ensembl Gene", "id": "ENSBTAG00000030881", "url": "https://www.ensembl.org/id/ENSBTAG00000030881" } ] } } ], "crossref": [ { "id": "F1N5A9", "url": "https://alphafold.ebi.ac.uk/entry/F1N5A9", "database": "AlphaFoldDB", "categories": [] }, { "id": "ENSBTAG00000030881", "url": "https://bgee.org/?page=gene&gene_id=ENSBTAG00000030881", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "IPR021280", "url": "https://www.ebi.ac.uk/interpro/entry/IPR021280", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR052724", "url": "https://www.ebi.ac.uk/interpro/entry/IPR052724", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR060492", "url": "https://www.ebi.ac.uk/interpro/entry/IPR060492", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "HSVNLMC", "url": "https://omabrowser.org/oma/group/HSVNLMC/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "PTHR16214", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR16214", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR16214:SF3", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR16214:SF3", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF11028", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF11028", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF28495", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF28495", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "A0AAA9SSL2", "url": "https://www.uniprot.org/uniprotkb/A0AAA9SSL2", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0AAA9SSL2-1", "url": "https://www.uniprot.org/uniprotkb/A0AAA9SSL2-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0AAA9T3H5", "url": "https://www.uniprot.org/uniprotkb/A0AAA9T3H5", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0AAA9T3H5-1", "url": "https://www.uniprot.org/uniprotkb/A0AAA9T3H5-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "F1N5A9", "url": "https://www.uniprot.org/uniprotkb/F1N5A9", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "F1N5A9-1", "url": "https://www.uniprot.org/uniprotkb/F1N5A9-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MATAGARLGGQAARVGARGAGGLCGGVAVFAAVAAVFTLTLPPSLPGGDSGELITAAHELGVAHPPGYPLFTLVAKLAILLFPFGSVAYRVNLLCGLFGAAAAALLFFTVFRLSGSYAGGILAAGVFSFSRLTWQWSIAAEVFSLNNLFVGLLMALTVHFEEAATAQERSKIAKIGALCCGLSLCNQHTIVLYVLCIIPWILFRLLKEKELSPGSLLKLSLCFSAGLLPYIYLPVSSYLNQARWTWGDQTTLLGFLTHFLREEYGTFSLAKSEIGSSMSEILLSQVTNMRTQLSFNIQALAVWANICLTRKDRQSPSLVWLFTGMFCIYSLFFAWRANLDISKPLFMGVVERFWMQSNAVVAVLAGIGLAALVSESNRVLNTNGLQYLEWLSAILFVTCQIYSNYSICDQRTNYVIDKFAKNLLSSMPRDAIILLRGDLPGNSLRYMHYCEGLRPDISLVDQEMMTYEWYLPKMAKHLPGVKFPGNRWNPVEGILSSGMVTFNLYHFLEVNKQKETFVCIGIHEGDPTWKKNYSLWPWGSCDKLVSSEIVFNPEEWIKLTRNIYNWTESYGRFDPSSWESVANEEMWQARMKTPFFIFNLAESASLPSNVKAQLYTHAYNLYKEIVYLRKEHPVNWHKNYAISCERMLRLQERSADPEVLLSETIRHFRLYTRKAQNDPQLADISVALKHLRKELRSLRNMKNG", "length": 704, "header": "tr|F1N5A9-1|F1N5A9_BOVIN Isoform 1 of Transmembrane protein 260 OS=Bos taurus OX=9913 GN=TMEM260 PE=4 SV=3 CANONICAL=F1N5A9-1" }, "isoforms": [ { "isoform_ac": "A0AAA9SSL2-1", "url": "https://www.uniprot.org/uniprotkb/A0AAA9SSL2/entry", "sequence": { "sequence": "MATAGARLGGQAARVGARGAGGLCGGVAVFAAVAAVFTLTLPPSLPGGDSGELITAAHELGVAHPPGYPLFTLVAKLAILLFPFGSVAYRVNLLCGLFGAAAAALLFFTVFRLSGSYAGGILAAGVFSFSRLTWQWSIAAEVFSLNNLFVGLLMALTVHFEEAATAQERSKIAKIGALCCGLSLCNQHTIVLYVLCIIPWILFRLLKEKELSPGSLLKLSLCFSAGLLPYIYLPVSSYLNQARWTWGDQTTLLGFLTHFLREEYGTFSLAKSEIGSSMSEILLSQVTNMRTQLSFNIQALAVWANICLTRKDRQSPSLVWLFTGMFCIYSLFFAWRANLDISKPLFMGVVERFWMQSNAVVAVLAGIGLAALVSESNRVLNTNGLQYLEWLSAILFVTCQIYSNYSICDQRTNYVIDKFAKNLLSSMPRDAIILLRGDLPGNSLRYMHYCEGLRPDISLVDQEMMTYEWYLPKMAKHLPGVKFPGNRWNPVEGILSSGMVTFNLYHFLEVNKQKETFVCIGIHEGDPTWKKNYSLWPWGSCDKLVSSEIVFNPEEWIKLTRNIYNWTESYGRFDPSSWESVANEEMWQARMKTPFFIFNLAESASLPSNVKAQLYTHAYNCTNTIKPDRRGFLQSNP", "length": 637, "header": "tr|A0AAA9SSL2-1|F1N5A9_BOVIN Computationally mapped isoform of Transmembrane protein 260 OS=Bos taurus OX=9913 GN=TMEM260 PE=4 SV=1 CANONICAL=F1N5A9-1" }, "locus": { "chromosome": "10", "start_pos": 69077822, "end_pos": 69005265, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000123552.2", "url": "https://www.ensembl.org/id/ENSBTAT00000123552.2" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000089374.1", "url": "https://www.ensembl.org/id/ENSBTAP00000089374.1" } ] } }, { "isoform_ac": "A0AAA9T3H5-1", "url": "https://www.uniprot.org/uniprotkb/A0AAA9T3H5/entry", "sequence": { "sequence": "MATAGARLGGQAARVGARGAGGLCGGVAVFAAVAAVFTLTLPPSLPGGDSGELITAAHELGVAHPPGYPLFTLVAKLAILLFPFGSVAYRVNLLCGLFGAAAAALLFFTVFRLSGSYAGGILAAGVFSFSRLTWQWSIAAEVFSLNNLFVGLLMALTVHFEEAATAQERSKIAKIGALCCGLSLCNQHTIVLYVLCIIPWILFRLLKEKAKSEIGSSMSEILLSQVTNMRTQLSFNIQALAVWANICLTRKDRQSPSLVWLFTGMFCIYSLFFAWRANLDISKPLFMGVVERFWMQSNAVVAVLAGIGLAALVSESNRVLNTNGLQYLEWLSAILFVTCQIYSNYSICDQRTNYVIDKFAKNLLSSMPRDAIILLRGDLPGNSLRYMHYCEGLRPDISLVDQEMMTYEWYLPKMAKHLPGVKFPGNRWNPVEGILSSGMVTFNLYHFLEVNKQKETFVCIGIHEGDPTWKKNYSLWPWGSCDKLVSSEIVFNPEEWIKLTRNIYNWTESYGRFDPSSWESVANEEMWQARMKTPFFIFNLAESASLPSNVKAQLYTHAYNLYKEIVYLRKEHPVNWHKNYAISCERMLRLQERSADPEVLLSETIRHFRLYTRKAQNDPQLADISVALKHLRKELRSLRNMKNG", "length": 644, "header": "tr|A0AAA9T3H5-1|F1N5A9_BOVIN Computationally mapped isoform of Transmembrane protein 260 OS=Bos taurus OX=9913 GN=TMEM260 PE=4 SV=1 CANONICAL=F1N5A9-1" }, "locus": { "chromosome": "10", "start_pos": 69075145, "end_pos": 69005265, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000130916.2", "url": "https://www.ensembl.org/id/ENSBTAT00000130916.2" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000090246.1", "url": "https://www.ensembl.org/id/ENSBTAP00000090246.1" } ] } }, { "isoform_ac": "F1N5A9-1", "url": "https://www.uniprot.org/uniprotkb/F1N5A9/entry", "sequence": { "sequence": "MATAGARLGGQAARVGARGAGGLCGGVAVFAAVAAVFTLTLPPSLPGGDSGELITAAHELGVAHPPGYPLFTLVAKLAILLFPFGSVAYRVNLLCGLFGAAAAALLFFTVFRLSGSYAGGILAAGVFSFSRLTWQWSIAAEVFSLNNLFVGLLMALTVHFEEAATAQERSKIAKIGALCCGLSLCNQHTIVLYVLCIIPWILFRLLKEKELSPGSLLKLSLCFSAGLLPYIYLPVSSYLNQARWTWGDQTTLLGFLTHFLREEYGTFSLAKSEIGSSMSEILLSQVTNMRTQLSFNIQALAVWANICLTRKDRQSPSLVWLFTGMFCIYSLFFAWRANLDISKPLFMGVVERFWMQSNAVVAVLAGIGLAALVSESNRVLNTNGLQYLEWLSAILFVTCQIYSNYSICDQRTNYVIDKFAKNLLSSMPRDAIILLRGDLPGNSLRYMHYCEGLRPDISLVDQEMMTYEWYLPKMAKHLPGVKFPGNRWNPVEGILSSGMVTFNLYHFLEVNKQKETFVCIGIHEGDPTWKKNYSLWPWGSCDKLVSSEIVFNPEEWIKLTRNIYNWTESYGRFDPSSWESVANEEMWQARMKTPFFIFNLAESASLPSNVKAQLYTHAYNLYKEIVYLRKEHPVNWHKNYAISCERMLRLQERSADPEVLLSETIRHFRLYTRKAQNDPQLADISVALKHLRKELRSLRNMKNG", "length": 704, "header": "tr|F1N5A9-1|F1N5A9_BOVIN Isoform 1 of Transmembrane protein 260 OS=Bos taurus OX=9913 GN=TMEM260 PE=4 SV=3 CANONICAL=F1N5A9-1" }, "locus": { "chromosome": "10", "start_pos": 69075145, "end_pos": 69005265, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000052373.4", "url": "https://www.ensembl.org/id/ENSBTAT00000052373.4" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000052546.3", "url": "https://www.ensembl.org/id/ENSBTAP00000052546.3" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [], "orthologs": [ { "uniprot_canonical_ac": "A0A8V0YZN2-1", "protein_name": "Transmembrane protein 260", "gene_name": "TMEM260", "tax_id": 9031, "organism": "Gallus gallus", "sequence": { "sequence": "MGAGSGSGAAAVAAAGAVGAAVVAVYAGTLPPGLPGGDAGELITAAYELGVAHPPGYPLFTLLAGLAMRLLPGGAAAGRVNLLCAVLGAAAAALLFYTVLRLSGSYAGGILAAGVFSFSRLTWQWSITAEVFSLNNLFVGLLMALTVHFEEASTAKERSKIARLGAFCCGLSLCNQHTIVLYIACIVPWVLFLLFRKMELSLGHLLKLGLCFLAGLLPYLYLPASSYLDRARWTWGDQTTFQGFLTHFLREEYGTFNLAKSESGSSMREMLVFQLEQMRSDLSLPVLALALIACFSTALPIKQQKSPVICLFAGMLCVYSLFFAWRANLDVTKPLFLGVVERFWMQSNVAVAVLAGLGLAALMSLGGAVLQGSRVLPWLEWLSAGALVAAQVWANYRDCDQSNNYIVDKFARNLLSSMPMGAVILLRGDLPGNALRYLHYVEGVRPDITLVDQEMMTYEWYLPKLAKHLPGVHFPGNRWNPVEGILPDGTLVFNLHHFLKANKHKEVFVCIGLHEGDSTWRRSYSLWPWGTCEKLVPTDAVFDPGEWIRLTRNLYNWTEEYGSFKPSSWEAVANEEMWQARMKTAFFIFGLAETASVPAEMKSQLYTLAYTLYKEIVSSHPHHPVNWHKNYAIACERMLRLHRVGEDPEVLLSETVKHFLLYTQKAEDDPQRQDILQAVNHLQKELQGLRGMKAELKRQAG", "length": 701 }, "evidence": [ { "id": "F1N5A9", "url": "https://omabrowser.org/oma/group/F1N5A9/", "database": "OMA" } ], "glygen_name": "Chicken", "common_name": "Chicken" }, { "uniprot_canonical_ac": "E7F5M2-1", "protein_name": "Protein O-mannosyl-transferase TMEM260 isoform X1", "gene_name": "tmem260", "tax_id": 7955, "organism": "Danio rerio", "sequence": { "sequence": "MSSDRWTWSLTGATVAGVSALYVGCAPRAVPGGDSGELITAACELGVAHPPGYPLFTMMSSLMLSLLPLSSPAHSINVLCAVFGAGASGALCFTVCRVAEPGPGAVLAGGVFAVSRLVWQWSVVAEVFSLNNLFVGVLFSLSACFHCADTVQQKKKFALWGALFCGLSLCNQHTLVLYVVVIIPWALLHLYTHNGLSFFDLVSLGTCFLAGFVPYMYLPVSSYLNRARWSWGDQTSVHGLLTHLLRAEYGTFSLAKTNESLNLLEMLRAQWNHCVNDLTVPVLALALLGMLLSLRSRLRCIFVCLIVTMVSIYSVFFAWRANLNIEKPLLLGVVERFWLQADAGVCVLAGLGLSWLVCCLTGHLGKGTVWNTGAWILTAGLISHMISLNHRDCDQSSNDVVDRFSREVVLSLPQGSLVLTRGDLPGNTLRYQHYCQSLRPDLSLVDQEMMTYNWYVAKLQRHLPGVTFPGHRWDPVNAVEKKTFSIEQFLKRNLHRPVFVCIGLTEGDPSWEGSFSRWPWGVCEQLLPVKTPFDPKKWAQKTHNLYNWSEPHDSFHPGSWERVANEEMWQARMKTAFFLFDLAENAEKEQQGRLYEISYKLYCQIVDSQVDYPANWDKNLALAAERLLQSGGRGYGLDSLMSRSIRHFSRYLKREPSDPQSKAIRSIITHLRKEREKFRDRQKA", "length": 684 }, "evidence": [ { "id": "F1N5A9", "url": "https://omabrowser.org/oma/group/F1N5A9/", "database": "OMA" } ], "glygen_name": "Zebrafish", "common_name": "Zebrafish" }, { "uniprot_canonical_ac": "F1M7C0-1", "protein_name": "Transmembrane protein 260", "gene_name": "Tmem260", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MGLHGDGGGPAAGAGPWRSGGLCGSVAVFAAVAAVFTLTLPRSLPGGDSGELITAAHELGVAHPPGYPLFTLVANLAITLFPFGSVAYRVNLLCGLFGAVAASLLFFTVFRLSGSRAGGILAAGVFSFSRLTWQWSIAAEVFSLNNLFVGLLMALTVRFEEATAAKERSKIAAIGAFSCGLSLCNQHTIVLYVLCIIPWILFRLLKEKELTLSLLLKLALAFSAGLLPYVYLPVSSYLSHARWTWGDQTTLRGFLTHFLREEYGTFSLAKSEVGSSASTVLLSQIINMKTELSFNIQALAVWANVCLPRKDRRKSSVVWLFTGMLCVYSLFFTWRANLDISKPLFMGVVERFWMQSNAVVAVLAGLGLATLVSETSRVLSWNGVRNLEWLSAALFIAYQVYSNYSICDQRTNNVIDQFARNLLNSMPPDAIILLRGDLPGNALRYLHYCEGLRPDVSLVDQEMMTYEWYLPKVARHLPGVHFPGDRWNPVEGVLPSGMVTFNLYHFLEMNKQKETFVCIGIHEGDPTWKKDYSLWPWGSCDKLVPSKIVFNPEEWIEHTRTIYNWTEEYGRFDPSSWESVANEEMWQARMKTPFFIFSLAESAAVPADVKAQLYTHAYKLYKEIVYLQEEHPVNWHKNYAIACERMLRLPGTGEDPEVLLSETIRHFHLYTQKAQNDPQRASIMAALKHLRRELRSLRNTKEV", "length": 703 }, "evidence": [ { "id": "F1N5A9", "url": "https://omabrowser.org/oma/group/F1N5A9/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "F1SSM4-1", "protein_name": "Transmembrane protein 260", "gene_name": "TMEM260", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MGLHGDGGGLAEGPAARVGPRRSRGLRGGVAVFAAVAAVFTLTLPPSVPGGDSGELITAAHELGVAHPPGYPLFTLVAKLAIILFPFGSVAYRVNLLCGLFGAVAAALLFFTVFRLSGSYAGGILAAGVFSFSRLTWQWSIAAEVFSLNNLFVGLLMALTVHFEEAATSQERSKIAKIGAFCCGLSLCNQHTIVLYVLCIIPWILFRLLKEKELSLGSLLNLSLFFSAGLLPYIYLPISSYLHQARWTWGDQTTLLGFLTHFLREEYGTFSLAKSEIGSSMSEILLSQLTNMRTQLSFNIQALAVWANICLARKDRQNPPLAWLFTGMFCIYSLFFAWRANLDISKPLFMGVVERFWMQSNAVVAVLAGIGLAALVSESNRVLNTNGLQFLEWLSATLFVTYQIYSNYSICDQRTNYVIDKFAKNLLASMPQDAIILLRGDLPGNSLRYLHYCEGLRPDISLVDQEMMTYEWYLPKMAKHLPGVKFPGNRWNPVEGILPSGMVTFNLYHFLKINKQKETFVCIGIHEGDPTWKKNYSLWPWGSCDKLVSSEIAFNPEEWIKLTRNIYNWTEEYGRFDPSSWESVANEEMWQARMKTPFFIFNLAETTSLPSDVKAQLYTHAYNLYKEIVYLRKEHPVNWHKNYAIACERMLRLQESGADPEVLLSETIRHFRLYTQKARNDPQLADISAALKHLRKELQSLRNRKNV", "length": 707 }, "evidence": [ { "id": "F1N5A9", "url": "https://omabrowser.org/oma/group/F1N5A9/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "Q8BMD6-1", "protein_name": "Protein O-mannosyl-transferase TMEM260", "gene_name": "Tmem260", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MGLHGDGGSPAAGAGPWRSGALRGSVAVFASVAAVFTLTLPRSLPGGDSGELITAAHELGVAHPPGYPLFTLLASLTITLFPFGSVAYRVNLLCGLFGAVAASLLFYTVFRLSGSHAGGILAAGVFSFSRLTWQWSIAAEVFSLNNLFVGLLMALTVRFEEATAAKERSKIAAIGAFSCGLSLCNQHTIVLYILCIIPWILFRLLKEKELTLSLLLRLTLAFSAGLLPYVYLPVSSYLSRARWTWGDQTTLRGFLTHFFREEYGTFSLAKSEVGSSVSTVLLSQVINMKTELSFNIQALAVWANICLARKDRRKSSVVWLFTGMLCLYSLFFAWRANLDISKPLFMGVVERFWLQSNAVVAVLAGLGLATLVSETNRVLHCTGIRNLEWLSAALFVAYQVYSNYSICDQRTNNVIDQFARNLLDSMPQDAIILLRGDLPGNALRYLHYCEGLRPDVSLVDQEMMTYEWYLPKMARHLPGVHFPGDRWNPVEGVLPSGMVTFNLYHFLEMNKQKETFVCIGIHEGDPTWKKDYSLWPWGSCDKLVPSKIVFNPEEWIERTRAIYNWTEAYERFGPSSWESVANEEMWQARMKTPFFIFSLAESAAVPADVKAQLYTHAYKLYKEIVYLQEEHPVNWHKNYAIACERMLRLPGTGIDPEVLLSEAIRHFHLYTQKAQNDPQRADIIAALKHLRRELQSLRNIKKV", "length": 703 }, "evidence": [ { "id": "F1N5A9", "url": "https://omabrowser.org/oma/group/F1N5A9/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q8MXQ3-1", "protein_name": "Protein O-mannosyl-transferase tmem260", "gene_name": "", "tax_id": 44689, "organism": "Dictyostelium discoideum", "sequence": { "sequence": "MNNSPTLSNTRNRKNNNNNSNSNSNSNNNNNNNNNNNNNSNNNNNNNNNVNRNVNNRNNNNNNIINVNNNVSSTTMNMAKDFMNWNDGIIEREDTQLQQQKDRCFKILKKSTIACIVLLFISCTIIYSMTQYPSVSGGDAGELIVVAHQFGVAHPPGYPLFTFLGYIFSHIIPSNTLSVAWKISFMSSMIGSIASIFIYLTVYLWVNNHWCGLLSAYMFTFSPLIWMYQIQGEVFSMNNMFVAMLMFLGVWYTRVRIFENERYNTAFWTSERIAYLSAFSCAIGLTNQHTLVLIVIPFAFWLMFISGRDQLWNIKILSNLVFYTLIGLSPYLLLFITPKLNRVKYSWGNTSTLRGFIKHFLREEYGTLQLYGGDGGVISLFTKISIYIENLIIQFGYIGLALSLIGLLNLLLGYNIRTFKWKSFGTMIIFSFLFYITFFFNLCNLPIDKPLYRGVFLRFFMQPNVIISITMGLGIKSIFGFLNRIQRDGGTAATTTTTISKIQKYLLPIIIILLVGNQIGFNYNLQDQSDNYSFYDYGHSVLDGLPRNTLLLVGGDLVTNVPMYLHLCEKVRPDIDILSMEIMSWEWFKITQSPLFQRVKFPGNVYHPYIPDGYSLKDFLDANINDRPIYIGGDFKSGDSSFQNDYYTISKGLTSQIIPKKDSHKFNTFKIIKTTFSTFPSFHIPNNTEKYPNDSWEHFMMEEMAVSLERAAETLLKEYLSQQNTESFKALELSVEILEKALTYVNDKCWSLKHLGICFDHLRYRVVQNVNNNNQQAQNKASNYSKQLLYFWKKYINQCTHEENTDQDWETIKKVIQLI", "length": 819 }, "evidence": [ { "id": "F1N5A9", "url": "https://omabrowser.org/oma/group/F1N5A9/", "database": "OMA" } ], "glygen_name": "Cellular slime mold", "common_name": "Social amoeba" }, { "uniprot_canonical_ac": "Q9NX78-1", "protein_name": "Protein O-mannosyl-transferase TMEM260", "gene_name": "TMEM260", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": 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"dolichyl-phosphate-mannose-protein mannosyltransferase activity", "id": "GO:0004169", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0004169", "evidence": [ { "database": "UniProtKB", "id": "F1N5A9", "url": "https://www.uniprot.org/uniprotkb/F1N5A9" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 1, "go_terms": [ { "name": "endoplasmic reticulum membrane", "id": "GO:0005789", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005789", "evidence": [ { "database": "UniProtKB", "id": "F1N5A9", "url": "https://www.uniprot.org/uniprotkb/F1N5A9" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 1, "go_terms": [ { "name": "protein maturation", "id": "GO:0051604", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0051604", "evidence": [ { "database": "UniProtKB", "id": "F1N5A9", "url": "https://www.uniprot.org/uniprotkb/F1N5A9" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 404, "end_pos": 406, "annotation": "n_glycosylation_sequon" }, { "start_pos": 532, "end_pos": 534, "annotation": "n_glycosylation_sequon" }, { "start_pos": 565, "end_pos": 567, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [ { "pdb_id": "AF-F1N5A9-F1", "pdb_chain": "global", "start_pos": 1, "end_pos": 704, "overlap": "1.0", "method": "AlphaFold", "type": "alphafold", "resolution": -1.0, "url": "https://data.glygen.org/ln2downloads/pdb/current/AF-F1N5A9-F1.pdb", "url_external": "https://alphafold.ebi.ac.uk/entry/F1N5A9" } ], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "F1N5A9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1N5A9" }, { "id": "PF11028", "database": "Pfam", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF11028" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "Protein O-mannosyl-transferase TMEM260 N-terminal", "eco_id": 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565, "end_pos": 567 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": 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"publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ], "tool_support": { "graph_view": "yes" } }, { "uniprot_canonical_ac": "F1N4Z7-1", "uniprot_ac": "F1N4Z7", "uniprot_id": "F1N4Z7_BOVIN", "mass": { "chemical_mass": 33023.0, "monoisotopic_mass": 33023.0 }, "refseq": { "ac": "XP_024837719", "name": "uncharacterized protein CCDC197 isoform X1", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_024837719" }, "gene_names": [ { "name": "CCDC197", "type": "recommended", "evidence": [ { "id": "F1N4Z7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1N4Z7" } ] }, { "name": "CCDC197", "type": "synonym", "evidence": [ { "id": "XP_024837719", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_024837719" } ] } ], "protein_names": [ { "name": "Coiled-coil domain containing 197", "type": "synonym", "evidence": [ { "id": "F1N4Z7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1N4Z7/entry#names_and_taxonomy" } ] }, { "name": "uncharacterized protein CCDC197 isoform X1", "type": "synonym", "evidence": [ { "id": "XP_024837719", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_024837719" } ] } ], "function": [], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Bos taurus", "taxid": 9913, "evidence": [ { "database": "UniProtKB", "id": "F1N4Z7", "url": "https://www.uniprot.org/uniprotkb/F1N4Z7" } ], "common_name": "Bovine", "glygen_name": "Bovine", "reference_species": "Bos taurus [9913]" } ], "gene": [ { "name": "CCDC197", "url": "https://www.uniprot.org/uniprotkb/F1N4Z7", "locus": { "chromosome": "21", "start_pos": 58617282, "end_pos": 58604263, "strand": "-", "evidence": [ { "database": "Ensembl Gene", "id": "ENSBTAG00000016112", "url": "https://www.ensembl.org/id/ENSBTAG00000016112" } ] } } ], "crossref": [ { "id": "F1N4Z7", "url": "https://alphafold.ebi.ac.uk/entry/F1N4Z7", "database": "AlphaFoldDB", "categories": [] }, { "id": "ENSBTAG00000016112", "url": "https://bgee.org/?page=gene&gene_id=ENSBTAG00000016112", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "617443", "url": "https://www.ncbi.nlm.nih.gov/gene/617443", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR051147", "url": "https://www.ebi.ac.uk/interpro/entry/IPR051147", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "CWSWDSF", "url": "https://omabrowser.org/oma/group/CWSWDSF/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "F1N4Z7", "url": "https://www.orthodb.org/?gene=F1N4Z7", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR21683", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR21683", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR21683:SF18", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR21683:SF18", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "XP_024837719", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_024837719", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0AAA9SSS2", "url": "https://www.uniprot.org/uniprotkb/A0AAA9SSS2", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0AAA9SSS2-1", "url": "https://www.uniprot.org/uniprotkb/A0AAA9SSS2-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "F1N4Z7", "url": "https://www.uniprot.org/uniprotkb/F1N4Z7", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "F1N4Z7-1", "url": "https://www.uniprot.org/uniprotkb/F1N4Z7-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MLAARDAGQEAGPSDPGNKDRGLQVLFQELCQLQAKQRKLKREVEKHKVFEDYLIKVLEKIPKGYNQGEEPEETPVAAMVEHYGKLFAVSQDIQKRLKAFLEMNQAVHKSLESLEEGHRALILRLKIRLCQLQRRCHRKQEQWQQLEHGFTLQKDVGSCEVGSKEAAANDDSEDLKCGTLELPRNELLNYVQVAINDMARQCCSAAHAVPRGMGLFSKLDLIQEFMLDKMETVRFISLLTGPIVCWTANNPNNQGLRSYPRPFRKHSVSEDSTPRNLFPSTQTSECFNLS", "length": 290, "header": "tr|F1N4Z7-1|F1N4Z7_BOVIN Isoform 1 of Coiled-coil domain containing 197 OS=Bos taurus OX=9913 GN=CCDC197 PE=4 SV=1 CANONICAL=F1N4Z7-1" }, "isoforms": [ { "isoform_ac": "A0AAA9SSS2-1", "url": "https://www.uniprot.org/uniprotkb/A0AAA9SSS2/entry", "sequence": { "sequence": "MLAARDAGQEAGPSDPGNKDRGLQVLFQELCQLQAKQRKLKREVEKHKVFEDYLIKVLEKIPKGYNQGEEPEETPVAAMVEHYGKLFAVSQDIQKRLKAFLEMNQAVHKSLESLEEGHRALILRLKIRLCQLQRRCHRKQEQWQQLEHGFTLQKDVGSCENELLNYVQVAINDMARQCCSAAHAVPRGMGLFSKLDLIQEFMLDKMETVRFISLLTGPIVCWTANNPNNQGLRSYPRPFRKHSVSEDSTPRNLFPSTQTSECFNLS", "length": 266, "header": "tr|A0AAA9SSS2-1|F1N4Z7_BOVIN Computationally mapped isoform of Coiled-coil domain containing 197 OS=Bos taurus OX=9913 GN=CCDC197 PE=4 SV=1 CANONICAL=F1N4Z7-1" }, "locus": { "chromosome": "21", "start_pos": 58617234, "end_pos": 58605116, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000130701.1", "url": "https://www.ensembl.org/id/ENSBTAT00000130701.1" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000088388.1", "url": "https://www.ensembl.org/id/ENSBTAP00000088388.1" } ] } }, { "isoform_ac": "F1N4Z7-1", "url": "https://www.uniprot.org/uniprotkb/F1N4Z7/entry", "sequence": { "sequence": "MLAARDAGQEAGPSDPGNKDRGLQVLFQELCQLQAKQRKLKREVEKHKVFEDYLIKVLEKIPKGYNQGEEPEETPVAAMVEHYGKLFAVSQDIQKRLKAFLEMNQAVHKSLESLEEGHRALILRLKIRLCQLQRRCHRKQEQWQQLEHGFTLQKDVGSCEVGSKEAAANDDSEDLKCGTLELPRNELLNYVQVAINDMARQCCSAAHAVPRGMGLFSKLDLIQEFMLDKMETVRFISLLTGPIVCWTANNPNNQGLRSYPRPFRKHSVSEDSTPRNLFPSTQTSECFNLS", "length": 290, "header": "tr|F1N4Z7-1|F1N4Z7_BOVIN Isoform 1 of Coiled-coil domain containing 197 OS=Bos taurus OX=9913 GN=CCDC197 PE=4 SV=1 CANONICAL=F1N4Z7-1" }, "locus": { "chromosome": "21", "start_pos": 58617234, "end_pos": 58605116, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000021447.6", "url": "https://www.ensembl.org/id/ENSBTAT00000021447.6" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000021447.5", "url": "https://www.ensembl.org/id/ENSBTAP00000021447.5" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [], "orthologs": [ { "uniprot_canonical_ac": "Q8NCU1-1", "protein_name": "Uncharacterized protein CCDC197", "gene_name": "CCDC197", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MAAMDTGQRADPSNPGDKEGDLQGLWQELYQLQAKQKKLKREVEKHKLFEDYLIKVLEKIPEGCTGWEEPEEVLVEATVKHYGKLFTASQDTQKRLEAFCQMIQAVHRSLESLEEDHRALIASRSGCVSCRRSATASRSSGGS", "length": 143 }, "evidence": [ { "id": "F1N4Z7", "url": "https://omabrowser.org/oma/group/F1N4Z7/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" } ], "go_annotation": 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"table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ], "tool_support": { "graph_view": "yes" } }, { "uniprot_canonical_ac": "F1N312-1", "uniprot_ac": "F1N312", "uniprot_id": "F1N312_BOVIN", "mass": { "chemical_mass": 161797.0, "monoisotopic_mass": 161797.0 }, "refseq": { "ac": "NP_001193235", "name": "zinc finger protein 608", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001193235" }, "gene_names": [ { "name": "ZNF608", "type": "recommended", "evidence": [ { "id": "F1N312", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1N312" } ] }, { "name": "ZNF608", "type": "synonym", "evidence": [ { "id": "NP_001193235", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001193235" } ] } ], "protein_names": [ { "name": "Zinc finger protein 608", "type": "synonym", "evidence": [ { "id": "F1N312", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1N312/entry#names_and_taxonomy" } ] }, { "name": "zinc finger protein 608", "type": "synonym", "evidence": [ { "id": "NP_001193235", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001193235" } ] } ], "function": [], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Bos taurus", "taxid": 9913, "evidence": [ { "database": "UniProtKB", "id": "F1N312", "url": "https://www.uniprot.org/uniprotkb/F1N312" } ], "common_name": "Bovine", "glygen_name": "Bovine", "reference_species": "Bos taurus [9913]" } ], "gene": [ { "name": "ZNF608", "url": "https://www.uniprot.org/uniprotkb/F1N312", "locus": { "chromosome": "7", "start_pos": 29124841, "end_pos": 29009360, "strand": "-", "evidence": [ { "database": "Ensembl Gene", "id": "ENSBTAG00000016137", "url": "https://www.ensembl.org/id/ENSBTAG00000016137" } ] } } ], "crossref": [ { "id": "ENSBTAG00000016137", "url": "https://bgee.org/?page=gene&gene_id=ENSBTAG00000016137", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "509992", "url": "https://www.ncbi.nlm.nih.gov/gene/509992", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR013087", "url": "https://www.ebi.ac.uk/interpro/entry/IPR013087", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR040010", "url": "https://www.ebi.ac.uk/interpro/entry/IPR040010", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "bta:509992", "url": "https://www.genome.jp/dbget-bin/www_bget?bta:509992", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "PNCAMDE", "url": "https://omabrowser.org/oma/group/PNCAMDE/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "F1N312", "url": "https://www.orthodb.org/?gene=F1N312", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR21564", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR21564", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR21564:SF4", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR21564:SF4", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF27627", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF27627", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "NP_001193235", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001193235", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0AAA9SU41", "url": "https://www.uniprot.org/uniprotkb/A0AAA9SU41", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0AAA9SU41-1", "url": "https://www.uniprot.org/uniprotkb/A0AAA9SU41-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "F1N312", "url": "https://www.uniprot.org/uniprotkb/F1N312", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "F1N312-1", "url": "https://www.uniprot.org/uniprotkb/F1N312-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MSVNISTAGKGVDPNTVDTYDSGDDWEIGVGNLIIDLDADLEKDRQKFEMNNSTNTTSSGNSKDCGGLASSGAGAPAALADGLKFASVQPSAPQGNSHKETSKSKVKRSKTSKDANKSLPSAALYGIPEISGTGKRQEVQGRPGEATGMNSALGQSVSGGGGGGGNPNSNSTSTGTSAATAGAASCGKSKEEKPGKSQSSRGAKRDKDAGKSRKDKHDLLQGHQNGSGSQAPSGGHLYGFGAKSNGGGASPFHCGGTGSGSVTAAGEVSKSAPDSGLMGNSMLVKKEEEEEESHRRIKKLKTEKVDPLFTVPAPPPPIASSLTPQLLPSYFSPSSSNIAAPVEQLLVRTRSVGVNTCEVGVVTEPECLGPCEPGTSVNLEGIVWHETEEGVLVVNVTWRNKTYVGTLLDCTKHDWAPPRFCESPTSDLEMRGGRGRGKRARSTAAAPGSEASFTESRGLQNKNRGGANGKGRRGSLNASGRRTPPNCAAEDIKASPSSTNKRKNKPPMELDLNSSSEDSKPGKRVRTNSRSTPTTPQGKPETTFLDQGCSSPVLIDCPHPNCNKKYKHINGLRYHQAHAHLDPENKLEFEPDSEDKISDCEEALSNVALECSEPSTSVSTYEQVKAPVSPGSGNPPGTPKGKRELLSNGPGSVIGAKAGKNSGKKKGLNNDLNNLPVISNMTATLDSCSAVDGSLTVEMPKLEAEGLIDKKTLGEKEKGKKANNCKMDKNLSKLKTARPIAPAPAPTPPQLIAIPTAAFPSTTTGTIPGLTTVVQATPKSPPLKPIQPKPTIMGEPITVNPALVSLKDKKKKEKRKLKDKEGKETGSPKMDAKLGKLEDAKGTGKDLSGHFLKDHLSKNEGLANGLSESQESRMASIKAEADKVYTFTDNAPSPSIGSASRMECSTLVNGQAPMAPLHVLTQNGAESSAAKTSSPAYSDISDAADDGGSDSRSEGVRSKTSSPSDILSSKDGSVKGHSSTTAQSSQMKESHSPYYHGYDPYYSPSYMHPGQMGASVAGNGGSTQGMKIKKESEEEADKKDKAEQLEAKKVDHNPASLQPQHQSVITQRHPALAQSLFYGQYAYGLYMDQKSLMATSPAYRQQYEKYYEDQRLAEQKMAQTGRGDCERKNELPLKELGKEDSKQKNMPSATVSKAPSTPEPNKNHSKLGPSVPNKTEETGKSQLLSSHQQQLQADSFKAKQMENHQLIKEAVEMKSVMDSMKQTGVDPTSRFKQDPDTRTWHHYVYQPKYLDPQKSEELDREKKLKEDSPRKTPNKESGVPSLPVSLTSIKEEPKEAKRPDSQSLDEGKLKNDDRKTPVNWKDSRGTRVAVSSPMSQHQSYIQYLHAYPYPQMYDPSHPAYRAVSPVLMHSYPGAYLSPGFHYPVYGKMSGREEAEKVNTSPSINTKTATESKALDLLQQHANQYRSKSPAPVEKASAEREREAERERDRHSPFGQRHLHTHHHTHVGMGYPLIPGQYDPFQGLTSAALVASQQVAAQASASGMFPAQRRE", "length": 1510, "header": "tr|F1N312-1|F1N312_BOVIN Isoform 1 of Zinc finger protein 608 OS=Bos taurus OX=9913 GN=ZNF608 PE=4 SV=3 CANONICAL=F1N312-1" }, "isoforms": [ { "isoform_ac": "A0AAA9SU41-1", "url": "https://www.uniprot.org/uniprotkb/A0AAA9SU41/entry", "sequence": { "sequence": "MSVNISTAGKGVDPNTVDTYDSGDDWEIGVGNLIIDLDADLEKDRQKFEMNNSTNTTSSGNSKDCGGLASSGAGAPAALADGLKFASVQPSAPQGNSHKETSKSKVKRSKTSKDANKSLPSAALYGIPEISGTGKRQEVQGRPGEATGMNSALGQSVSGGGGGGGNPNSNSTSTGTSAATAGAASCGKSKEEKPGKSQSSRGAKRDKDAGKSRKDKHDLLQGHQNGSGSQAPSGGHLYGFGAKSNGGGASPFHCGGTGSGSVTAAGEVSKSAPDSGLMGNSMLVKKEEEEEESHRRIKKLKTEKVDPLFTVPAPPPPIASSLTPQLLPSYFSPSSSNIAAPVEQLLVRTRSVGVNTCEVGVVTEPECLGPCEPGTSVNLEGIVWHETEEGVLVVNVTWRNKTYVGTLLDCTKHDWAPPRIQIQGHGIIMYTNPNTWIHKSQKNLIEKRN", "length": 449, "header": "tr|A0AAA9SU41-1|F1N312_BOVIN Computationally mapped isoform of Zinc finger protein 608 OS=Bos taurus OX=9913 GN=ZNF608 PE=4 SV=1 CANONICAL=F1N312-1" }, "locus": { "chromosome": "7", "start_pos": 29119287, "end_pos": 29020390, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000116713.1", "url": "https://www.ensembl.org/id/ENSBTAT00000116713.1" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000087668.1", "url": "https://www.ensembl.org/id/ENSBTAP00000087668.1" } ] } }, { "isoform_ac": "F1N312-1", "url": "https://www.uniprot.org/uniprotkb/F1N312/entry", "sequence": { "sequence": "MSVNISTAGKGVDPNTVDTYDSGDDWEIGVGNLIIDLDADLEKDRQKFEMNNSTNTTSSGNSKDCGGLASSGAGAPAALADGLKFASVQPSAPQGNSHKETSKSKVKRSKTSKDANKSLPSAALYGIPEISGTGKRQEVQGRPGEATGMNSALGQSVSGGGGGGGNPNSNSTSTGTSAATAGAASCGKSKEEKPGKSQSSRGAKRDKDAGKSRKDKHDLLQGHQNGSGSQAPSGGHLYGFGAKSNGGGASPFHCGGTGSGSVTAAGEVSKSAPDSGLMGNSMLVKKEEEEEESHRRIKKLKTEKVDPLFTVPAPPPPIASSLTPQLLPSYFSPSSSNIAAPVEQLLVRTRSVGVNTCEVGVVTEPECLGPCEPGTSVNLEGIVWHETEEGVLVVNVTWRNKTYVGTLLDCTKHDWAPPRFCESPTSDLEMRGGRGRGKRARSTAAAPGSEASFTESRGLQNKNRGGANGKGRRGSLNASGRRTPPNCAAEDIKASPSSTNKRKNKPPMELDLNSSSEDSKPGKRVRTNSRSTPTTPQGKPETTFLDQGCSSPVLIDCPHPNCNKKYKHINGLRYHQAHAHLDPENKLEFEPDSEDKISDCEEALSNVALECSEPSTSVSTYEQVKAPVSPGSGNPPGTPKGKRELLSNGPGSVIGAKAGKNSGKKKGLNNDLNNLPVISNMTATLDSCSAVDGSLTVEMPKLEAEGLIDKKTLGEKEKGKKANNCKMDKNLSKLKTARPIAPAPAPTPPQLIAIPTAAFPSTTTGTIPGLTTVVQATPKSPPLKPIQPKPTIMGEPITVNPALVSLKDKKKKEKRKLKDKEGKETGSPKMDAKLGKLEDAKGTGKDLSGHFLKDHLSKNEGLANGLSESQESRMASIKAEADKVYTFTDNAPSPSIGSASRMECSTLVNGQAPMAPLHVLTQNGAESSAAKTSSPAYSDISDAADDGGSDSRSEGVRSKTSSPSDILSSKDGSVKGHSSTTAQSSQMKESHSPYYHGYDPYYSPSYMHPGQMGASVAGNGGSTQGMKIKKESEEEADKKDKAEQLEAKKVDHNPASLQPQHQSVITQRHPALAQSLFYGQYAYGLYMDQKSLMATSPAYRQQYEKYYEDQRLAEQKMAQTGRGDCERKNELPLKELGKEDSKQKNMPSATVSKAPSTPEPNKNHSKLGPSVPNKTEETGKSQLLSSHQQQLQADSFKAKQMENHQLIKEAVEMKSVMDSMKQTGVDPTSRFKQDPDTRTWHHYVYQPKYLDPQKSEELDREKKLKEDSPRKTPNKESGVPSLPVSLTSIKEEPKEAKRPDSQSLDEGKLKNDDRKTPVNWKDSRGTRVAVSSPMSQHQSYIQYLHAYPYPQMYDPSHPAYRAVSPVLMHSYPGAYLSPGFHYPVYGKMSGREEAEKVNTSPSINTKTATESKALDLLQQHANQYRSKSPAPVEKASAEREREAERERDRHSPFGQRHLHTHHHTHVGMGYPLIPGQYDPFQGLTSAALVASQQVAAQASASGMFPAQRRE", "length": 1510, "header": "tr|F1N312-1|F1N312_BOVIN Isoform 1 of Zinc finger protein 608 OS=Bos taurus OX=9913 GN=ZNF608 PE=4 SV=3 CANONICAL=F1N312-1" }, "locus": { "chromosome": "7", "start_pos": 29124372, "end_pos": 29020390, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000021480.7", "url": "https://www.ensembl.org/id/ENSBTAT00000021480.7" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000021480.6", "url": "https://www.ensembl.org/id/ENSBTAP00000021480.6" } ] } } ], "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "other", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 747, "start_aa": "Thr", "end_pos": 747, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr747", "evidence": [ { "id": "", "database": "GlyGen", "url": "https://data.glygen.org/" } ], "filter_code": "000000000000000010000.00000000001000.0.01000" } ], "phosphorylation": [], "glycation": [], "keywords": [ "glycoprotein", "glycoprotein_predicted" ], "publication": [], "pathway": [ { "id": "bta:509992", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?bta:509992", "resource": "KEGG Pathway" } ], "orthologs": [ { "uniprot_canonical_ac": "D3ZNA1-1", "protein_name": "Zinc finger protein 608", "gene_name": "Zfp608", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MSVNVSTAGKGVDPNTVDTYDSGDDWEIGVGNLIIDLDADLEKDRQKFEMNNSTNTTTNNTKDCGGPASNGTCATSALADGLKFASVQPSAPQGNSHKETSKSKVKRAKTSKDANKSLPSAALYGIPEISTGKRQEVQGRPGEATGMNSALGQSVSGGGGGNPNSNGTSTGTSAATAGAGSCGKSKEEKPGKSHSSRGAKRDKDAARSRKDKHDVLQGHQNGGGGQGPSGGGHLYGFGAKSNGSGASPFHCGGAGSGSVGAAGEVTKTAPDSTLMGNSMLVKKEEEEEESHRRIKKLKTEKVDPLFTVPAPPPPIASSLAPQIPPSYFSPSSSNIAAPVEQLLVRTRSVGVNTCEVGVVTEPECLGPCEPGTSVNLEGIVWHETEEGVLVVNVTWRNKTYVGTLLDCTKHDWAPPRFCESPTSDLEMRGGRGRGKRARSAAAAPGAEVSFTESRGLQSKNRGGANGKGRRGSLNASGRRTPPNCAAEDVKASPSSTNKRKNKPPMELDLNSSSEDSKPGKRVRTNSRSTPTTPQGKPETTFLDQGCSSPVLIDCPHPNCNKKYKHINGLRYHQAHAHLDPENKLEFEPDSEDKISDCEEALSNVALDCNEPSTSVSSYDQVKAPGSPGAGNPPGTPKGKREHVSNGPGPIIGSKTGKNSGKKRGLNNELSNLPVISNMTATVDICSAADGSLAAEMPKLEAEGLIDKKSLGDKEKGKKANNCKMDKNLSKLKSARPIAPAPAPTPPQLIAIPTAAFTSTTTGTIPGLPSLTTTVVQATPKSPPLKPIQPKPTIMGEPITVNPALVSLKDRKKKEKRKLKDKEGKDTGGPKMDSKLGKLEDAKVASKDLSGHFLKDHLGKSEGLANGLSESQESRMASIKAEADKVYTFTDNAPSPSIGSASRMECSTLVNGQAPMAPLHVLTQNGAESAAAKTSSPAYSDISDAADDGGSDSRSEGMRSKASSPSETFSNKDGVVKGHPQTSAQPSQLKESHSPYYHGYEPYYSPSYMHPGQVGAPAAGNGGSAQGMKIKKESEEDAEKKDKAEQLESKKAEHPSASLQPQHQSVITQRHPALAQSLYYGQYAYGLYMDQKSLMATSPAYRQQYEKYYEDQRLAEQKLAQSGRGDCERKAELPLKELGKEDSKQKNIPSATVSKAPSTPEPNKNHSKVGPSVPNKTEETGKSQLLSSHQQQLQADSFKAKQMENHQLIKEAVEMKSVMDSMKQTGVDPASRFKQDPESRTWHHYVYQPKYLDQQKPEELDREKKLKEDSPRKTPNKESGTPSLPVSLTNIKEEPKDGKRPDSQSVEESKLKNEDRKTPVNWKDSRGTRVAVSSPMSQHQSYIQYLHAYPYPQMYDPSHPAYRAVSPVLMHSYPGAYLSPGFHYPVYGKMSGREEAEKVNTSPSISTKTASEAKALDLLQHHANQYRSKSPAPVEKASTEREREREAERERDRHSPFSQRHLHTHHHTHVGMGYPLIPGQYDPFQGLTSAALVASQQVAAQASASGMFPAQRRE", "length": 1513 }, "evidence": [ { "id": "F1N312", "url": "https://omabrowser.org/oma/group/F1N312/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "Q56A10-1", "protein_name": "Zinc finger protein 608", "gene_name": "Znf608", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MSVNVSTAGKGVDPNTVDTYDSGDDWEIGVGNLIIDLDADLEKDRQKFEMNNSTNTTTNTTKDCGGPASNGTCSTSALADGLKFASVQPSAPQGNSHKETSKSKVKRAKTSKDANKSLPSAALYGIPEISSTGKRQEVQGRPGEATGMNSALGQSVSGGGSSNPNSNGTSTGTSAATAGAGSCGKSKEEKPGKSHSSRGAKRDKDAARSRKEKHDLLQGHQNGGGGQAPSGGHLYGFGTKSNGSGASPFHCGGAGSGSVGAAGEVSKTAPDSTLMGNSMLVKKEEEEEESHRRIKKLKTEKVDPLFTVPAPPPPIASSLAPQIPPSYFPPSSSNIAAPVEQLLVRTRSVGVNTCEVGVVTEPECLGPCEPGTSVNLEGIVWHETEEGVLVVNVTWRNKTYVGTLLDCTKHDWAPPRFCESPTSDLEMRGGRGRGKRARSAAAAPGSEVSFTESRGLQSKNRGGANGKGRRGSLNASGRRTPPNCAAEDIKASPSSTNKRKNKPPMELDLNSSSEDSKPGKRVRTNSRSTPTTPQGKPETTFLDQGCSSPVLIDCPHPNCNKKYKHINGLRYHQAHAHLDPENKLEFEPDSEDKISDCEEALSNVALECNESSTSVSSYDQTKAPGSPGAGNPPGTPKGKREHVSNGPGPIIGSKTGKNSGKKRGLNNELNNLPVISNMTAALDICSATDSNLTAEMPKLEAEGLIDKKSLGDKEKGKKANNCKMDKNLSKLKSARPIAPAPAPTPPQLIAIPTAAFTSTTTGTIPGLPSLTTTVVQATPKSPPLKPIQPKPTIMGEPITVNPALVSLKDRKKKEKRKLKDKEGKETGGPKMDAKLGKLEEAKAASKDLSGHFLKDHLGKSEGLANGLSESQESRMASIKAEADKVYTFTDNAPSPSIGSASRMECSTLVNGQAPMAPLHVLTQNGAESAAAKTSSPAYSDISDAADDGGSDSRSEGMRSKASSPSDTFSNKDGVVKGHPSTSAQPSQLKESHSPYYHGYEPYYSPSYMHPGQVGAPAAGNGGSTQGMKIKKESEEDAEKKDKAEQLESKKVDHTSAPLQPQHQSVITQRHPALAQSLYYGQYAYGLYMDQKSLMATSPAYRQQYEKYYEDQRLAEQKMAQSGRGDCERKAELPLKELGKEDNKQKNMPSATISKAPSTPEPNKNHSKLGPSVPNKTEETGKSQLLSSHQQQLQADSFKAKQMENHQLIKEAVEMKSVMDSMKQTGVDPTSRFKQDPESRTWHHYVYQPKYLDQQKPEELDREKKLKEDSPRKTPNKESGVSSLPVSLTNIKEEPKEGKRPDSQSVEENKLKNDDRKTPVNWKDSRGTRVAVSSPMSQHQSYIQYLHAYPYPQMYDPSHPAYRAVSPVLMHSYPGAYLSPGFHYPVYGKMSGREEAEKVNTSPSINTKTASEAKALDLLQHHANQYRSKSPAPVEKASTEREREAERERDRHSPFSQRHLHTHHHTHVGMGYPLIPGQYDPFQGLTSAALVASQQVAAQASASGMFPAQRRE", "length": 1511 }, "evidence": [ { "id": "F1N312", "url": "https://omabrowser.org/oma/group/F1N312/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q9ULD9-1", "protein_name": "Zinc finger protein 608", "gene_name": "ZNF608", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MSVNISTAGKGVDPNTVDTYDSGDDWEIGVGNLIIDLDADLEKDRQKFEMNNSTTTTSSSNSKDCGGPASSGAGATAALADGLKFASVQASAPQGNSHKETSKSKVKRSKTSKDANKSLPSAALYGIPEISSTGKRQEVQGRPGEATGMNSALGQSVSSGGSGNPNSNSTSTSTSAATAGAGSCGKSKEEKPGKSQSSRGAKRDKDAGKSRKDKHDLLQGHQNGSGSQAPSGGHLYGFGAKSNGGGASPFHCGGTGSGSVAAAGEVSKSAPDSGLMGNSMLVKKEEEEEESHRRIKKLKTEKVDPLFTVPAPPPPISSSLTPQILPSYFSPSSSNIAAPVEQLLVRTRSVGVNTCEVGVVTEPECLGPCEPGTSVNLEGIVWHETEEGVLVVNVTWRNKTYVGTLLDCTKHDWAPPRFCESPTSDLEMRGGRGRGKRARSAAAAPGSEASFTESRGLQNKNRGGANGKGRRGSLNASGRRTPPNCAAEDIKASPSSTNKRKNKPPMELDLNSSSEDNKPGKRVRTNSRSTPTTPQGKPETTFLDQGCSSPVLIDCPHPNCNKKYKHINGLRYHQAHAHLDPENKLEFEPDSEDKISDCEEGLSNVALECSEPSTSVSAYDQLKAPASPGAGNPPGTPKGKRELMSNGPGSIIGAKAGKNSGKKKGLNNELNNLPVISNMTAALDSCSAADGSLAAEMPKLEAEGLIDKKNLGDKEKGKKATNCKTDKNLSKLKSARPIAPAPAPTPPQLIAIPTATFTTTTTGTIPGLPSLTTTVVQATPKSPPLKPIQPKPTIMGEPITVNPALVSLKDKKKKEKRKLKDKEGKETGSPKMDAKLGKLEDSKGASKDLPGHFLKDHLNKNEGLANGLSESQESRMASIKAEADKVYTFTDNAPSPSIGSASRLECSTLVNGQAPMAPLHVLTQNGAESSAAKTSSPAYSDISDAADDGGSDSRSEGMRSKASSPSDIISSKDSVVKGHSSTTAQSSQLKESHSPYYHSYDPYYSPSYMHPGQVGAPAAGNSGSTQGMKIKKESEEDAEKKDKAEQLDSKKVDHNSASLQPQHQSVITQRHPALAQSLYYGQYAYGLYMDQKSLMATSPAYRQQYEKYYEDQRLAEQKMAQTGRGDCERKSELPLKELGKEETKQKNMPSATISKAPSTPEPNKNHSKLGPSVPNKTEETGKSQLLSNHQQQLQADSFKAKQMENHQLIKEAVEMKSVMDSMKQTGVDPTSRFKQDPDSRTWHHYVYQPKYLDQQKSEELDREKKLKEDSPRKTPNKESGVPSLPVSLTSIKEEPKEAKHPDSQSMEESKLKNDDRKTPVNWKDSRGTRVAVSSPMSQHQSYIQYLHAYPYPQMYDPSHPAYRAVSPVLMHSYPGAYLSPGFHYPVYGKMSGREETEKVNTSPSVNTKTTTESKALDLLQQHANQYRSKSPAPVEKATAEREREAERERDRHSPFGQRHLHTHHHTHVGMGYPLIPGQYDPFQGLTSAALVASQQVAAQASASGMFPGQRRE", 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"categories": [ "Protein Classification" ] }, { "id": "PTHR24083", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR24083", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00104", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00104", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF00105", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00105", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "NP_001422083", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001422083", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0AAA9SUY1", "url": "https://www.uniprot.org/uniprotkb/A0AAA9SUY1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0AAA9SUY1-1", "url": "https://www.uniprot.org/uniprotkb/A0AAA9SUY1-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "F6Q8S4", "url": "https://www.uniprot.org/uniprotkb/F6Q8S4", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "F6Q8S4-1", "url": "https://www.uniprot.org/uniprotkb/F6Q8S4-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MRLSKTLVDMDMADYSAALDPAYTTLEFENVQVLTMGNDTSPSEGANLNAPNSLGVSALCAICGDRATGKHYGASSCDGCKGFFRRSVRKNHMYSCRFSRQCVVDKDKRNQCRYCRLKKCFRAGMKKEAVQNERDRISTRRSSYEDSSLPSINALLQAEVLSQQITSPVSGINGDIRAKKIASIADVCESMKEQLLVLVEWAKYIPAFCELPLDDQVALLRAHAGEHLLLGATKRSMVFKDVLLLGNDYIVPRHCPELAEMSRVSVRILDELVLPFQELQIDDNEYACLKAIIFFDPDAKGLSDPGKIKRLRSQVQVSLEDYINDRQYDSRGRFGELLLLLPTLQSITWQMIEQIQFIKLFGMAKIDNLLQEMLLGGSSSEAPHAHHPLHPHLMPEHMGTNVIVANTMPAHLSNGQMCEWPRPRGQAATPETPQPSPPGGSGSEPYKLLPGAIATIVKPPSAIPQPTITKQEVI", "length": 474, "header": "tr|F6Q8S4-1|F6Q8S4_BOVIN Isoform 1 of Hepatocyte nuclear factor 4 alpha OS=Bos taurus OX=9913 GN=HNF4A PE=3 SV=1 CANONICAL=F6Q8S4-1" }, "isoforms": [ { "isoform_ac": "A0AAA9SUY1-1", "url": "https://www.uniprot.org/uniprotkb/A0AAA9SUY1/entry", "sequence": { "sequence": "MVSVNAPLGAPVESPYDTSPSEGANLNAPNSLGVSALCAICGDRATGKHYGASSCDGCKGFFRRSVRKNHMYSCRFSRQCVVDKDKRNQCRYCRLKKCFRAGMKKEAVQNERDRISTRRSSYEDSSLPSINALLQAEVLSQQITSPVSGINGDIRAKKIASIADVCESMKEQLLVLVEWAKYIPAFCELPLDDQVALLRAHAGEHLLLGATKRSMVFKDVLLLGNDYIVPRHCPELAEMSRVSVRILDELVLPFQELQIDDNEYACLKAIIFFDPDAKGLSDPGKIKRLRSQVQVSLEDYINDRQYDSRGRFGELLLLLPTLQSITWQMIEQIQFIKLFGMAKIDNLLQEMLLGGSSSEAPHAHHPLHPHLMPEHMGTNVIVANTMPAHLSNGQMCEWPRPRGQAATPETPQPSPPGGSGSEPYKLLPGAIATIVKPPSAIPQPTITKQEVI", "length": 452, "header": "tr|A0AAA9SUY1-1|F6Q8S4_BOVIN Computationally mapped isoform of Hepatocyte nuclear factor 4 alpha OS=Bos taurus OX=9913 GN=HNF4A PE=3 SV=1 CANONICAL=F6Q8S4-1" }, "locus": { "chromosome": "13", "start_pos": 72852313, "end_pos": 72789048, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000114818.2", "url": "https://www.ensembl.org/id/ENSBTAT00000114818.2" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000086980.1", "url": "https://www.ensembl.org/id/ENSBTAP00000086980.1" } ] } }, { "isoform_ac": "F6Q8S4-1", "url": "https://www.uniprot.org/uniprotkb/F6Q8S4/entry", "sequence": { "sequence": "MRLSKTLVDMDMADYSAALDPAYTTLEFENVQVLTMGNDTSPSEGANLNAPNSLGVSALCAICGDRATGKHYGASSCDGCKGFFRRSVRKNHMYSCRFSRQCVVDKDKRNQCRYCRLKKCFRAGMKKEAVQNERDRISTRRSSYEDSSLPSINALLQAEVLSQQITSPVSGINGDIRAKKIASIADVCESMKEQLLVLVEWAKYIPAFCELPLDDQVALLRAHAGEHLLLGATKRSMVFKDVLLLGNDYIVPRHCPELAEMSRVSVRILDELVLPFQELQIDDNEYACLKAIIFFDPDAKGLSDPGKIKRLRSQVQVSLEDYINDRQYDSRGRFGELLLLLPTLQSITWQMIEQIQFIKLFGMAKIDNLLQEMLLGGSSSEAPHAHHPLHPHLMPEHMGTNVIVANTMPAHLSNGQMCEWPRPRGQAATPETPQPSPPGGSGSEPYKLLPGAIATIVKPPSAIPQPTITKQEVI", "length": 474, "header": "tr|F6Q8S4-1|F6Q8S4_BOVIN Isoform 1 of Hepatocyte nuclear factor 4 alpha OS=Bos taurus OX=9913 GN=HNF4A PE=3 SV=1 CANONICAL=F6Q8S4-1" }, "locus": { "chromosome": "13", "start_pos": 72852313, "end_pos": 72825800, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000016078.8", "url": "https://www.ensembl.org/id/ENSBTAT00000016078.8" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000016078.6", "url": "https://www.ensembl.org/id/ENSBTAP00000016078.6" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [ { "title": "Chicken ovalbumin upstream promoter transcription factor II (COUP-TFII) and hepatocyte nuclear factor 4gamma (HNF-4gamma) and HNF-4alpha regulate the bovine growth hormone receptor 1A promoter through a common DNA element.", "journal": "Journal of molecular endocrinology", "date": "2004-06", "authors": "Xu Q, Walther N, Jiang H", "evidence": [ { "database": "RefSeq", "id": "NP_001422083", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001422083" } ], "reference": [ { "type": "PubMed", "id": "15171724", "url": "https://glygen.org/publication/PubMed/15171724" } ] }, { "title": "Tetra-primer ARMS-PCR identifies the novel genetic variations of bovine HNF-4\u03b1 gene associating with growth traits.", "journal": "Gene", "date": "2014-08-10", "authors": "Wang Zi-nian, Li 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"MAAQRRSLLQSEQQPSWTDDLPLCHLSGVGSASNRSYSADGKGTESHPPEDNWLKFRSENNCFLYGVFNGYDGNRVTNFVAQRLSAELLLGQLSAEHTEADVRRVLLQAFDVVERSFLESIDDALAEKASLQSQLPEGVPQHQLPPQYQKILERLKTLEREVSGGAMAVVAVLLSNRLYVANVGTNRALLCKSTVDGLQVTQLNMDHTTENEDELFRLSQLGLDAGKLKQVGVICGQESTRRIGDYKVKYGYTDIDLLSAAKSKPIIAEPEIHGAQPLDGVTGFLVLMSEGLYKALEAAHGPGQANQEIAAMIDTEFAKQTSLDAVAQAVVDRVKRIHSDTFASGGERAKFCPRHEDMTLLVRNFGYPLGELSQPTPAPAPAAGGRVYPVSVPYSSTQSTSKTSVTLSLVMPSQGQLVNGAHSASTLDEATPTLTNQSPTLTLQSTNTHTQSSSSSSDGGLFRSRPTHSLPPGEDGRVEPYVDFAEFYRLWSVDHGEQSVATAP", "length": 504 }, "evidence": [ { "id": "F6QID7", "url": "https://omabrowser.org/oma/group/F6QID7/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "Q15750-1", "protein_name": "TGF-beta-activated kinase 1 and MAP3K7-binding protein 1", "gene_name": "TAB1", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MAAQRRSLLQSEQQPSWTDDLPLCHLSGVGSASNRSYSADGKGTESHPPEDSWLKFRSENNCFLYGVFNGYDGNRVTNFVAQRLSAELLLGQLNAEHAEADVRRVLLQAFDVVERSFLESIDDALAEKASLQSQLPEGVPQHQLPPQYQKILERLKTLEREISGGAMAVVAVLLNNKLYVANVGTNRALLCKSTVDGLQVTQLNVDHTTENEDELFRLSQLGLDAGKIKQVGIICGQESTRRIGDYKVKYGYTDIDLLSAAKSKPIIAEPEIHGAQPLDGVTGFLVLMSEGLYKALEAAHGPGQANQEIAAMIDTEFAKQTSLDAVAQAVVDRVKRIHSDTFASGGERARFCPRHEDMTLLVRNFGYPLGEMSQPTPSPAPAAGGRVYPVSVPYSSAQSTSKTSVTLSLVMPSQGQMVNGAHSASTLDEATPTLTNQSPTLTLQSTNTHTQSSSSSSDGGLFRSRPAHSLPPGEDGRVEPYVDFAEFYRLWSVDHGEQSVVTAP", "length": 504 }, "evidence": [ { "id": "F6QID7", "url": "https://omabrowser.org/oma/group/F6QID7/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "Q8CF89-1", "protein_name": "TGF-beta-activated kinase 1 and MAP3K7-binding protein 1", "gene_name": "Tab1", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MAAQRRSLLQSEQQPSWTDDLPLCHLSGVGSASNRSYSADGKGTESHPPEDNWLKFRSENNCFLYGVFNGYDGNRVTNFVAQRLSAELLLGQLNTEHTEADVRRVLLQAFDVVERSFLESIDDALAEKASLQSQLPEGVPQHQLPPQYQKILERLKALEREISGGAMAVVAVLLNSKLYVANVGTNRALLCKSTVDGLQVTQLNMDHTTENEDELFRLSQLGLDAGKIKQMGVICGQESTRRIGDYKVKYGYTDIDLLSAAKSKPIIAEPEIHGAQPLDGVTGFLVLMSEGLYKALEAAHGPGQANQEIAAMIDTEFAKQTSLDAVAQAVVDRVKRIHSDTFASGGERAKFCPRHEDMTLLVRNFGYPLGEMSQPTPTPAPGGRVYPVSVPYSSAQSTSKTSVTLSLVMPSQGQMVNGSHSASTLDEATPTLTNQSPTLTLQSTNTHTQSSSSSSDGGLFRSRPAHSLPPGEDGRVEPYVDFAEFYRLWSVDHGEQSVMTAP", "length": 502 }, "evidence": [ { "id": "F6QID7", "url": "https://omabrowser.org/oma/group/F6QID7/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" } ], "go_annotation": { "categories": [ { "name": "Molecular Function", "total": 5, "go_terms": [ { "name": "kinase activator activity", "id": "GO:0019209", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0019209", "evidence": [ { "database": "UniProtKB", "id": "F6QID7", "url": "https://www.uniprot.org/uniprotkb/F6QID7" } ], "pmid": "" }, { "name": "protein serine/threonine phosphatase activity", "id": "GO:0004722", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0004722", "evidence": [ { "database": "UniProtKB", "id": "F6QID7", "url": "https://www.uniprot.org/uniprotkb/F6QID7" } ], "pmid": "" }, { "name": "molecular adaptor activity", "id": "GO:0060090", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0060090", "evidence": [ { "database": "UniProtKB", "id": "F6QID7", "url": "https://www.uniprot.org/uniprotkb/F6QID7" } ], "pmid": "" }, { "name": "identical protein binding", "id": "GO:0042802", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0042802", "evidence": [ { "database": "UniProtKB", "id": "F6QID7", "url": "https://www.uniprot.org/uniprotkb/F6QID7" } ], "pmid": "" }, { "name": "protein serine/threonine kinase activator activity", "id": "GO:0043539", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0043539", "evidence": [ { "database": "UniProtKB", "id": "F6QID7", "url": "https://www.uniprot.org/uniprotkb/F6QID7" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 2, "go_terms": [ { "name": "cytosol", "id": "GO:0005829", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005829", "evidence": [ { "database": "UniProtKB", "id": "F6QID7", "url": "https://www.uniprot.org/uniprotkb/F6QID7" } ], "pmid": "" }, { "name": "endoplasmic reticulum membrane", "id": "GO:0005789", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005789", "evidence": [ { "database": "UniProtKB", "id": "F6QID7", "url": "https://www.uniprot.org/uniprotkb/F6QID7" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 6, "go_terms": [ { "name": "signal transduction", "id": "GO:0007165", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007165", "evidence": [ { "database": "UniProtKB", "id": "F6QID7", "url": "https://www.uniprot.org/uniprotkb/F6QID7" } ], "pmid": "" }, { "name": "positive regulation of intracellular signal transduction", "id": "GO:1902533", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:1902533", "evidence": [ { "database": "UniProtKB", "id": "F6QID7", "url": "https://www.uniprot.org/uniprotkb/F6QID7" } ], "pmid": "" }, { "name": "canonical NF-kappaB signal transduction", "id": "GO:0007249", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007249", "evidence": [ { "database": "UniProtKB", "id": "F6QID7", "url": "https://www.uniprot.org/uniprotkb/F6QID7" } ], "pmid": "" }, { "name": "non-canonical NF-kappaB signal transduction", "id": "GO:0038061", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0038061", "evidence": [ { "database": "UniProtKB", "id": "F6QID7", "url": "https://www.uniprot.org/uniprotkb/F6QID7" } ], "pmid": "" }, { "name": "regulation of MAPK cascade", "id": "GO:0043408", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0043408", "evidence": [ { "database": "UniProtKB", "id": "F6QID7", "url": "https://www.uniprot.org/uniprotkb/F6QID7" } ], "pmid": "" }, { "name": "positive regulation of cGAS/STING signaling pathway", "id": "GO:0141111", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0141111", "evidence": [ { "database": "UniProtKB", "id": "F6QID7", "url": "https://www.uniprot.org/uniprotkb/F6QID7" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 34, "end_pos": 36, "annotation": "n_glycosylation_sequon" }, { "start_pos": 436, "end_pos": 438, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [ { "pdb_id": "AF-F6QID7-F1", "pdb_chain": "global", "start_pos": 1, "end_pos": 504, "overlap": "1.0", "method": "AlphaFold", "type": "alphafold", "resolution": -1.0, "url": "https://data.glygen.org/ln2downloads/pdb/current/AF-F6QID7-F1.pdb", "url_external": "https://alphafold.ebi.ac.uk/entry/F6QID7" } ], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "F6QID7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F6QID7" }, { "id": "PS51746", "database": "PROSITE", "url": "https://prosite.expasy.org/PS51746" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "PPM-type phosphatase", "eco_id": "ECO_0000259", "start_pos": 28, "end_pos": 365, "start_aa": "Gly", "end_aa": "Phe", "glycosite_overlap": [] } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" }, { "name": "homologset.oma", "label": "OMA Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 34, "end_pos": 36 }, { "start_pos": 436, "end_pos": 438 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { 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"F1N4W7", "uniprot_id": "F1N4W7_BOVIN", "mass": { "chemical_mass": 31511.0, "monoisotopic_mass": 31511.0 }, "refseq": {}, "gene_names": [], "protein_names": [ { "name": "NmrA-like family domain-containing protein 1", "type": "recommended", "evidence": [ { "id": "F1N4W7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1N4W7/entry#names_and_taxonomy" } ] } ], "function": [], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Bos taurus", "taxid": 9913, "evidence": [ { "database": "UniProtKB", "id": "F1N4W7", "url": "https://www.uniprot.org/uniprotkb/F1N4W7" } ], "common_name": "Bovine", "glygen_name": "Bovine", "reference_species": "Bos taurus [9913]" } ], "gene": [ { "name": "", "url": "https://www.uniprot.org/uniprotkb/F1N4W7", "locus": {} } ], "crossref": [ { "id": "F1N4W7", "url": "https://alphafold.ebi.ac.uk/entry/F1N4W7", "database": "AlphaFoldDB", "categories": [] }, { "id": "ENSBTAG00000011305", "url": "https://bgee.org/?page=gene&gene_id=ENSBTAG00000011305", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "cd05251", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd05251", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "IPR008030", "url": "https://www.ebi.ac.uk/interpro/entry/IPR008030", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR036291", "url": "https://www.ebi.ac.uk/interpro/entry/IPR036291", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR051164", "url": "https://www.ebi.ac.uk/interpro/entry/IPR051164", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "PTHR42748", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR42748", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR42748:SF10", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR42748:SF10", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF05368", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF05368", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "A0AAA9SWI5", "url": "https://www.uniprot.org/uniprotkb/A0AAA9SWI5", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0AAA9SWI5-1", "url": "https://www.uniprot.org/uniprotkb/A0AAA9SWI5-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "F1N4W7", "url": "https://www.uniprot.org/uniprotkb/F1N4W7", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "F1N4W7-1", "url": "https://www.uniprot.org/uniprotkb/F1N4W7-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MASAKLPLRTLSSGRLCGRAMLEGKKYVVRALTRDVTQPKAQVLRDLGAEVVKGDLNDKASVEAALKGAYGAFLVTNSWDHFSKEKEVCQASTFVPQGKVVADVAKSQGLKHVVYSGLENVKRLTNGKLEVLHFDGKGEVEEYFWSIAYFENFLGPLKPVKASDGDYYTLALPMGDVPMDGISVADIGAVVCSIFNSPEEFVGKAVGLSAEALTIQQYADVLSKGLGKEITPEAYQKLEFPGAKEMANMCRFYQMKPDRDIQLTHRLNPKVKSFSQFISENQAALKSS", "length": 288, "header": "tr|F1N4W7-1|F1N4W7_BOVIN Isoform 1 of NmrA-like family domain-containing protein 1 OS=Bos taurus OX=9913 GN= PE=3 SV=3 CANONICAL=F1N4W7-1" }, "isoforms": [ { "isoform_ac": "A0AAA9SWI5-1", "url": "https://www.uniprot.org/uniprotkb/A0AAA9SWI5/entry", "sequence": { "sequence": "KVELLSGLWGGGSGRLCGRAMLEGKKYVVRALTRDVTQPKAQVLRDLGAEVVKGDLNDKASVEAALKGAYGAFLVTNSWDHFSKEKEVCQGKVVADVAKSQGLKHVVYSGLENVKRLTNGKLEVLHFDGKGEVEEYFWSIAYFENFLGPLKPVKASDGDYYTLALPMGDVPMDGISVADIGAVVCSIFNSPEEFVGKAVGLSAEALTIQQYADVLSKGLGKEITPEAYQKLEFPGAKEMANMCRFYQMKPDRDIQLTHRLNPKVLSDFNFLKNLCRGFSGELGVQ", "length": 285, "header": "tr|A0AAA9SWI5-1|F1N4W7_BOVIN Computationally mapped isoform of NmrA-like family domain-containing protein 1 OS=Bos taurus OX=9913 GN= PE=3 SV=1 CANONICAL=F1N4W7-1" }, "locus": { "chromosome": "1", "start_pos": 81269724, "end_pos": 81253741, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000116575.1", "url": "https://www.ensembl.org/id/ENSBTAT00000116575.1" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000090837.1", "url": "https://www.ensembl.org/id/ENSBTAP00000090837.1" } ] } }, { "isoform_ac": "F1N4W7-1", "url": "https://www.uniprot.org/uniprotkb/F1N4W7/entry", "sequence": { "sequence": "MASAKLPLRTLSSGRLCGRAMLEGKKYVVRALTRDVTQPKAQVLRDLGAEVVKGDLNDKASVEAALKGAYGAFLVTNSWDHFSKEKEVCQASTFVPQGKVVADVAKSQGLKHVVYSGLENVKRLTNGKLEVLHFDGKGEVEEYFWSIAYFENFLGPLKPVKASDGDYYTLALPMGDVPMDGISVADIGAVVCSIFNSPEEFVGKAVGLSAEALTIQQYADVLSKGLGKEITPEAYQKLEFPGAKEMANMCRFYQMKPDRDIQLTHRLNPKVKSFSQFISENQAALKSS", "length": 288, "header": "tr|F1N4W7-1|F1N4W7_BOVIN Isoform 1 of NmrA-like family domain-containing protein 1 OS=Bos taurus OX=9913 GN= PE=3 SV=3 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"database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MASRKAGTRGKAAATKQAQRGSSNVFSMFEQAQIQEFKEAFSCIDQNRDGIICKSDLRETYSQLGKVNVPEEELDAMLQEGKGPINFTVFLTLFGEKLNGTDPEEAILSAFRLFDPSGKGVVNKDEFRQLLLTQADKFSPAEVEQMFALTPMDLAGNIDYKSLCYIITHGDEKEE", "length": 175, "header": "tr|F1N2V9-1|F1N2V9_BOVIN Isoform 1 of Myosin light chain 7 OS=Bos taurus OX=9913 GN=MYL7 PE=4 SV=2 CANONICAL=F1N2V9-1" }, "isoforms": [ { "isoform_ac": "A0AAA9SXS0-1", "url": "https://www.uniprot.org/uniprotkb/A0AAA9SXS0/entry", "sequence": { "sequence": "IRGLGPCPCSSQHPGPPHLLPCLGCGLLPLETVAPPPHRPSAASTRTVTASSASRTLERPTPSSVRAPVSCLAQPLSHQGPGSELLPGPACTPVLAHTTHPPLEHIPSTSLPPPSERSLPLVARIGEGQPSPTQGHSRALCPSNTPTGKVNVPEEELDAMLQEGKGPINFTVFLTLFGEKLNGTDPEEAILSAFRLFDPSGKGVVNKDEFRQLLLTQADKFSPAEVEQMFALTPMDLAGNIDYKSLCYIITHGDEKEE", "length": 258, "header": "tr|A0AAA9SXS0-1|F1N2V9_BOVIN Computationally mapped isoform of Myosin light chain 7 OS=Bos taurus OX=9913 GN=MYL7 PE=4 SV=1 CANONICAL=F1N2V9-1" }, "locus": { 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} ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [ { "id": "bta:508257", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?bta:508257", "resource": "KEGG Pathway" }, { "id": "R-BTA-445355", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-BTA-445355", "resource": "Reactome", "description": "Smooth Muscle Contraction" } ], "orthologs": [ { "uniprot_canonical_ac": "F1M7K3-1", "protein_name": "Myosin light chain 7", "gene_name": "Myl7", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MASRKAGTRGKAAATKQAQRGSSNVFSMFEQAQIQEFKEAFSCIDQNRDGIICKSDLKETYSQLGRVSVPEEELDAMLQEGKGPINFTVFLTLFGEKLNGTDPEEAILSAFRMFDPSGQGVVNKEEFKQLLMTQADKFSPAEVEQLFALTPMDLTGNIDYKSLCYIITHGDEKEE", "length": 175 }, "evidence": [ { "id": "F1N2V9", "url": "https://omabrowser.org/oma/group/F1N2V9/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "F1SSF9-1", "protein_name": "Myosin regulatory light chain 2, atrial isoform", "gene_name": "MYL7", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MASRKAGTRSKAAATKQAQRGSSNVFSMFEQAQIQEFKEAFSCIDQNRDGIICKSDLRETYSQLGKVNVPEEELDAMLQEGKGPINFTVFLTLFGEKLNGTDPEEAILSAFRLFDPSGKGVVNKDQFKQLLLTQADKFSPAEVEQMFALTPMDLAGNIDYKSLCYIITHGDEKEE", "length": 175 }, "evidence": [ { "id": "F1N2V9", "url": "https://omabrowser.org/oma/group/F1N2V9/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "P18432-1", "protein_name": "Myosin regulatory light chain 2", "gene_name": "Mlc2", "tax_id": 7227, "organism": "Drosophila melanogaster", "sequence": { "sequence": "MADEKKKVKKKKTKEEGGTSETASEAASEAATPAPAATPAPAASATGSKRASGGSRGSRKSKRAGSSVFSVFSQKQIAEFKEAFQLMDADKDGIIGKNDLRAAFDSVGKIANDKELDAMLGEASGPINFTQLLTLFANRMATSGANDEDEVVIAAFKTFDNDGLIDGDKFREMLMNFGDKFTMKEVDDAYDQMVIDDKNQIDTAALIEMLTGKGEEEEEEAA", "length": 222 }, "evidence": [ { "id": "F1N2V9", "url": 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"MASRKAGTRGKAAATKQAQRGSSNVFSMFEQAQIQEFKEAFSCIDQNRDGIICKSDLKETYSQLGRVSVPEEELDAMLQEGKGPINFTVFLTLFGEKLNGTDPEEAILSAFRMFDPSGQGVVNKEEFKQLLMTQADKFSPAEVEQLFALTPMDLAGNIDYKSLCYIITHGDEKEE", "length": 175 }, "evidence": [ { "id": "F1N2V9", "url": "https://omabrowser.org/oma/group/F1N2V9/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" } ], "go_annotation": { "categories": [ { "name": "Molecular Function", "total": 1, "go_terms": [ { "name": "calcium ion binding", "id": "GO:0005509", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005509", "evidence": [ { "database": "UniProtKB", "id": "F1N2V9", "url": "https://www.uniprot.org/uniprotkb/F1N2V9" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 3, "go_terms": [ { "name": "myosin complex", "id": "GO:0016459", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016459", "evidence": [ { "database": "UniProtKB", "id": "F1N2V9", "url": "https://www.uniprot.org/uniprotkb/F1N2V9" } ], "pmid": "" }, { "name": "cytoplasm", "id": "GO:0005737", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005737", "evidence": [ { "database": "UniProtKB", "id": "F1N2V9", "url": "https://www.uniprot.org/uniprotkb/F1N2V9" } ], "pmid": "" }, { "name": "myofibril", "id": "GO:0030016", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030016", "evidence": [ { "database": "UniProtKB", "id": "F1N2V9", "url": "https://www.uniprot.org/uniprotkb/F1N2V9" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 2, "go_terms": [ { "name": "heart contraction", "id": "GO:0060047", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0060047", "evidence": [ { "database": "UniProtKB", "id": "F1N2V9", "url": "https://www.uniprot.org/uniprotkb/F1N2V9" } ], "pmid": "" }, { "name": "cardiac muscle tissue development", "id": "GO:0048738", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0048738", "evidence": [ { "database": "UniProtKB", "id": "F1N2V9", "url": "https://www.uniprot.org/uniprotkb/F1N2V9" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 86, "end_pos": 88, "annotation": "n_glycosylation_sequon" }, { "start_pos": 99, "end_pos": 101, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [ { "pdb_id": "AF-F1N2V9-F1", "pdb_chain": "global", "start_pos": 1, "end_pos": 175, "overlap": "1.0", "method": "AlphaFold", "type": "alphafold", "resolution": -1.0, "url": "https://data.glygen.org/ln2downloads/pdb/current/AF-F1N2V9-F1.pdb", "url_external": "https://alphafold.ebi.ac.uk/entry/F1N2V9" } ], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "F1N2V9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1N2V9" }, { "id": "PS50222", "database": "PROSITE", "url": "https://prosite.expasy.org/PS50222" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "EF-hand", "eco_id": "ECO_0000259", "start_pos": 32, "end_pos": 67, "start_aa": "Ala", "end_aa": "Val", "glycosite_overlap": [] } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" }, { "name": "homologset.oma", "label": "OMA Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 86, "end_pos": 88 }, { "start_pos": 99, "end_pos": 101 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", 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"field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ], "tool_support": { "graph_view": "yes" } }, { "uniprot_canonical_ac": "F6R631-1", "uniprot_ac": "F6R631", "uniprot_id": "F6R631_BOVIN", "mass": { "chemical_mass": 33756.0, "monoisotopic_mass": 33756.0 }, "refseq": { "ac": "XP_010807394", "name": "heterogeneous nuclear ribonucleoproteins C1/C2 isoform X1", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_010807394" }, "gene_names": [ { "name": "HNRNPC", "type": "recommended", "evidence": [ { "id": "F6R631", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F6R631" } ] }, { "name": "HNRNPC", "type": "synonym", "evidence": [ { "id": "XP_010807394", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_010807394" } ] }, { "name": "HNRPC", "type": "synonym", "evidence": [ { "id": "XP_010807394", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_010807394" } ] } ], "protein_names": [ { "name": "Heteroous nuclear ribonucleoprotein C", "type": "synonym", "evidence": [ { "id": "F6R631", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F6R631/entry#names_and_taxonomy" } ] }, { "name": "heterogeneous nuclear ribonucleoproteins C1/C2 isoform X1", "type": "synonym", "evidence": [ { "id": "XP_010807394", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_010807394" } ] } ], "function": [ { "annotation": "Binds pre-mRNA and nucleates the assembly of 40S hnRNP particles. Interacts with poly-U tracts in the 3'-UTR or 5'-UTR of mRNA and modulates the stability and the level of translation of bound mRNA molecules. Single HNRNPC tetramers bind 230-240 nucleotides. Trimers of HNRNPC tetramers bind 700 nucleotides. May play a role in the early steps of spliceosome assembly and pre-mRNA splicing. N6-methyladenosine (m6A) has been shown to alter the local structure in mRNAs and long non-coding RNAs (lncRNAs) via a mechanism named 'm(6)A-switch', facilitating binding of HNRNPC, leading to regulation of mRNA splicing.", "evidence": [ { "database": "UniProtKB", "id": "A0AAA9SY76", "url": "https://www.uniprot.org/uniprotkb/A0AAA9SY76#function" }, { "database": "UniProtKB", "id": "ARBA00045185", "url": "https://www.uniprot.org/uniprotkb/ARBA00045185#function" }, { "database": "UniProtKB", "id": "F6R631", "url": "https://www.uniprot.org/uniprotkb/F6R631#function" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Bos taurus", "taxid": 9913, "evidence": [ { "database": "UniProtKB", "id": "F6R631", "url": "https://www.uniprot.org/uniprotkb/F6R631" } ], "common_name": "Bovine", "glygen_name": "Bovine", "reference_species": "Bos taurus [9913]" } ], "gene": [ { "name": "HNRNPC", "url": "https://www.uniprot.org/uniprotkb/F6R631", "locus": {} } ], "crossref": [ { "id": "F6R631", "url": "https://alphafold.ebi.ac.uk/entry/F6R631", "database": "AlphaFoldDB", "categories": [] }, { "id": "cd12603", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd12603", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "510852", "url": "https://www.ncbi.nlm.nih.gov/gene/510852", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR000504", "url": "https://www.ebi.ac.uk/interpro/entry/IPR000504", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR012677", "url": "https://www.ebi.ac.uk/interpro/entry/IPR012677", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR017347", "url": "https://www.ebi.ac.uk/interpro/entry/IPR017347", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR035979", "url": "https://www.ebi.ac.uk/interpro/entry/IPR035979", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR051186", "url": "https://www.ebi.ac.uk/interpro/entry/IPR051186", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "PTHR13968", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR13968", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR13968:SF3", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR13968:SF3", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00076", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00076", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "XP_010807394", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_010807394", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0AAA9SY76", "url": "https://www.uniprot.org/uniprotkb/A0AAA9SY76", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0AAA9SY76-1", "url": "https://www.uniprot.org/uniprotkb/A0AAA9SY76-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "F6R631", "url": "https://www.uniprot.org/uniprotkb/F6R631", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "F6R631-1", "url": "https://www.uniprot.org/uniprotkb/F6R631-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MASNVTNKTDPRSMNSRVFIGNLNTLVVKKSDVEAIFSKYGKIVGCSVHKGFAFVQYVNERNARAAVAGEDGRMIAGQVLDINLAAEPKVNRGKAGVKRSAAEMYGSVPEHPSPSPLLSSSFDLDYDFQRDYYDRMYSYPARVPPPPPIARAVVPSKRQRVSGNTSRRGKSGFNSKSGQRGSSSKSGKLKGDDLQTIKKELTQIKQKVDSLLESLEKIEKEQSKQGVEMKNDKSEEEQSSSSLKKDETNVKMESEGGADDSAEEGDLLDDDDNEDRGDDQLELIKDDEKEAEEGEDDRDSANGEDDS", "length": 307, "header": "tr|F6R631-1|F6R631_BOVIN Isoform 1 of Heteroous nuclear ribonucleoprotein C OS=Bos taurus OX=9913 GN=HNRNPC PE=3 SV=1 CANONICAL=F6R631-1" }, "isoforms": [ { "isoform_ac": "A0AAA9SY76-1", "url": "https://www.uniprot.org/uniprotkb/A0AAA9SY76/entry", "sequence": { "sequence": "MASNVTNKTDPRSMNSRVFIGNLNTLVVKKSDVEAIFSKYGKIVGCSVHKGFAFVQYVNERNARAAVAGEDGRMIAGQVLDINLAAEPKVNRGKAGVKRSAAEMYGSVPEHPSPSPLLSSSFDLDYDFQRDYYDRMYSYPARVPPPPPIARAVVPSKRQRVSGNTSRRGKSGFNSKSGQRGSSSKSGKLKGDDLQTIKKELTQIKQKVDSLLESLEKIEKEQSKQGAGVDQG", "length": 232, "header": "tr|A0AAA9SY76-1|F6R631_BOVIN Computationally mapped isoform of Heteroous nuclear ribonucleoprotein C OS=Bos taurus OX=9913 GN=HNRNPC PE=3 SV=1 CANONICAL=F6R631-1" }, "locus": { "chromosome": "10", "start_pos": 25925375, "end_pos": 25905542, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000092227.2", "url": "https://www.ensembl.org/id/ENSBTAT00000092227.2" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000088277.1", "url": "https://www.ensembl.org/id/ENSBTAP00000088277.1" } ] } }, { "isoform_ac": "F6R631-1", "url": "https://www.uniprot.org/uniprotkb/F6R631/entry", "sequence": { "sequence": "MASNVTNKTDPRSMNSRVFIGNLNTLVVKKSDVEAIFSKYGKIVGCSVHKGFAFVQYVNERNARAAVAGEDGRMIAGQVLDINLAAEPKVNRGKAGVKRSAAEMYGSVPEHPSPSPLLSSSFDLDYDFQRDYYDRMYSYPARVPPPPPIARAVVPSKRQRVSGNTSRRGKSGFNSKSGQRGSSSKSGKLKGDDLQTIKKELTQIKQKVDSLLESLEKIEKEQSKQGVEMKNDKSEEEQSSSSLKKDETNVKMESEGGADDSAEEGDLLDDDDNEDRGDDQLELIKDDEKEAEEGEDDRDSANGEDDS", "length": 307, "header": "tr|F6R631-1|F6R631_BOVIN Isoform 1 of Heteroous nuclear ribonucleoprotein C OS=Bos taurus OX=9913 GN=HNRNPC PE=3 SV=1 CANONICAL=F6R631-1" }, "locus": { "chromosome": "10", "start_pos": 25925439, "end_pos": 25905542, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000001668.5", "url": "https://www.ensembl.org/id/ENSBTAT00000001668.5" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000001668.3", "url": "https://www.ensembl.org/id/ENSBTAP00000001668.3" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [], "orthologs": [], "go_annotation": { "categories": [ { "name": "Molecular Function", "total": 2, "go_terms": [ { "name": "RNA binding", "id": "GO:0003723", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003723", "evidence": [ { "database": "UniProtKB", "id": "F6R631", "url": "https://www.uniprot.org/uniprotkb/F6R631" } ], "pmid": "" }, { "name": "mRNA binding", "id": "GO:0003729", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003729", "evidence": [ { "database": "UniProtKB", "id": "F6R631", "url": "https://www.uniprot.org/uniprotkb/F6R631" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 2, "go_terms": [ { "name": "ribonucleoprotein complex", "id": "GO:1990904", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:1990904", "evidence": [ { "database": "UniProtKB", "id": "F6R631", "url": "https://www.uniprot.org/uniprotkb/F6R631" } ], "pmid": "" }, { "name": "pronucleus", "id": "GO:0045120", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0045120", "evidence": [ { "database": "UniProtKB", "id": "F6R631", "url": "https://www.uniprot.org/uniprotkb/F6R631" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 164, "end_pos": 166, "annotation": "n_glycosylation_sequon" }, { "start_pos": 4, "end_pos": 6, "annotation": "n_glycosylation_sequon" }, { "start_pos": 7, "end_pos": 9, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "F6R631", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F6R631" }, { "id": "PS50102", "database": "PROSITE", "url": "https://prosite.expasy.org/PS50102" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "RRM", "eco_id": "ECO_0000259", "start_pos": 16, "end_pos": 87, "start_aa": "Ser", "end_aa": "Glu", "glycosite_overlap": [] } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 164, "end_pos": 166 }, { "start_pos": 4, "end_pos": 6 }, { "start_pos": 7, "end_pos": 9 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ], "tool_support": { "graph_view": "yes" } }, { "uniprot_canonical_ac": "A0AAA9TWF2-1", "uniprot_ac": "A0AAA9TWF2", "uniprot_id": "A0AAA9TWF2_BOVIN", "mass": { "chemical_mass": 64061.0, "monoisotopic_mass": 64061.0 }, "refseq": {}, "gene_names": [ { "name": "AATF", "type": "recommended", "evidence": [ { "id": "A0AAA9TWF2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TWF2" } ] } ], "protein_names": [ { "name": "Apoptosis antagonizing transcription factor", "type": "synonym", "evidence": [ { "id": "A0AAA9TWF2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TWF2/entry#names_and_taxonomy" } ] } ], "function": [], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Bos taurus", "taxid": 9913, "evidence": [ { "database": "UniProtKB", "id": "A0AAA9TWF2", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TWF2" } ], "common_name": "Bovine", "glygen_name": "Bovine", "reference_species": "Bos taurus [9913]" } ], "gene": [ { "name": "AATF", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TWF2", "locus": { "chromosome": "19", "start_pos": 13421110, "end_pos": 13312159, "strand": "-", "evidence": [ { "database": "Ensembl Gene", "id": "ENSBTAG00000021927", "url": "https://www.ensembl.org/id/ENSBTAG00000021927" } ] } } ], "crossref": [ { "id": "A0AAA9TWF2", "url": "https://alphafold.ebi.ac.uk/entry/A0AAA9TWF2", "database": "AlphaFoldDB", "categories": [] }, { "id": "ENSBTAG00000021927", "url": "https://bgee.org/?page=gene&gene_id=ENSBTAG00000021927", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "IPR012617", "url": "https://www.ebi.ac.uk/interpro/entry/IPR012617", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR025160", "url": "https://www.ebi.ac.uk/interpro/entry/IPR025160", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR039223", "url": "https://www.ebi.ac.uk/interpro/entry/IPR039223", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "E1BDL9", "url": "https://www.orthodb.org/?gene=E1BDL9", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR15565", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR15565", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR15565:SF0", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR15565:SF0", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF08164", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF08164", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF13339", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF13339", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "A0AAA9SYF6", "url": "https://www.uniprot.org/uniprotkb/A0AAA9SYF6", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0AAA9SYF6-1", "url": "https://www.uniprot.org/uniprotkb/A0AAA9SYF6-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0AAA9TWF2", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TWF2", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0AAA9TWF2-1", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TWF2-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "E1BDL9", "url": "https://www.uniprot.org/uniprotkb/E1BDL9", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "E1BDL9-1", "url": "https://www.uniprot.org/uniprotkb/E1BDL9-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MTMAGPQSLALQLEQLLNPRPREADPEADPEEATAAKVIDRFDEGEDGEGDFQAVGSIRKLASASLLDTDKRYSGKTTSRKAWKEDHWEQTLSGSSDKEISDEDGSADGDSEGLGLEESDEEAMSAEDQEGGDEGDSSLAWKKRSGSHSQTSSGFSVQSISDFEKFTEGMDDLGSSEEEEEDEEESGMEEGESEEDSEDASEEDKAEARASEDDGVVMTFSEVRVSEEVEKGRAVKNQIALWDQLLEGRIKLQKALLTTNQLPQPDVFPVFKDKGGPEFASALKNSHKALKALLRSLVDLQEELLFQYPDTRYLVDGTKPKAESEEEISSDDEELVEKKKPQRRAPTKRKLETEDYPSFMAKRFADFTVYRNRTLQKWHDKTKLASGKLGKASGFGAFERSILTQIDHILMDKERLLRRTQTKRSVYRVLGKPEPAVQPVPESLPGQPEILPEAPANAHLKDLDEEIFDDDDFYHQLLRELIERKTSSLDPNDQVAMGRQWLAIQKLRSKIHKKVDRKASKGRKLRFHVLSKLLSFMAPIDHTTMNDDARTELYRSLFGQLNPRDDSHGA", "length": 570, "header": "tr|A0AAA9TWF2-1|A0AAA9TWF2_BOVIN Isoform 1 of Apoptosis antagonizing transcription factor OS=Bos taurus OX=9913 GN=AATF PE=3 SV=2 CANONICAL=A0AAA9TWF2-1" }, "isoforms": [ { "isoform_ac": "A0AAA9SYF6-1", "url": "https://www.uniprot.org/uniprotkb/A0AAA9SYF6/entry", "sequence": { "sequence": "MTMAGPQSLALQLEQLLNPRPREADPEADPEEATAAKVIDRFDEGEDGEGDFQAVGSIRKLASASLLDTDKRYSGKTTSRKAWKEDHWEQTLSGSSDKEISDEDGSADGDSEGLGLEESDEEAMSAEDQEGGDEGDSSLAWKKRSGSHSQTSSGFSVQSISDFEKFTEGMDDLGSSEEEEEDEEESGMEEGESEEDSEDASEEDKAEARASEDDGVVMTFSEVRVSEEVEKGRAVKNQIALWDQLLEGRIKLQKALLTTNQLPQPDVFPVFKDKGGPEFASALKNSHKALKALLRSLVDLQEELLFQYPDTRYLVDGTKPKAESEEEISSDDEELVEKKKPQRRAPTKRKLETEDYPSFMAKRFADFTVYRNRTLQKWHDKTKLASGKLGKGFGAFERSILTQIDHILMDKERLLRRTQTKRSVYRVLGKPEPAVQPVPESLPGQPEILPEAPANAHLKDLDEEIFDDDDFYHQLLRELIERKTSSLDPNDQVAMGRQWLAIQKLRSKIHKKVDRKASKGRKLRTELYRSLFGQLNPRDDSHGA", "length": 544, "header": "tr|A0AAA9SYF6-1|A0AAA9TWF2_BOVIN Computationally mapped isoform of Apoptosis antagonizing transcription factor OS=Bos taurus OX=9913 GN=AATF PE=3 SV=1 CANONICAL=A0AAA9TWF2-1" }, "locus": { "chromosome": "19", "start_pos": 13420106, "end_pos": 13312414, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000121472.2", "url": "https://www.ensembl.org/id/ENSBTAT00000121472.2" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000090399.1", "url": "https://www.ensembl.org/id/ENSBTAP00000090399.1" } ] } }, { "isoform_ac": "A0AAA9TWF2-1", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TWF2/entry", "sequence": { "sequence": "MTMAGPQSLALQLEQLLNPRPREADPEADPEEATAAKVIDRFDEGEDGEGDFQAVGSIRKLASASLLDTDKRYSGKTTSRKAWKEDHWEQTLSGSSDKEISDEDGSADGDSEGLGLEESDEEAMSAEDQEGGDEGDSSLAWKKRSGSHSQTSSGFSVQSISDFEKFTEGMDDLGSSEEEEEDEEESGMEEGESEEDSEDASEEDKAEARASEDDGVVMTFSEVRVSEEVEKGRAVKNQIALWDQLLEGRIKLQKALLTTNQLPQPDVFPVFKDKGGPEFASALKNSHKALKALLRSLVDLQEELLFQYPDTRYLVDGTKPKAESEEEISSDDEELVEKKKPQRRAPTKRKLETEDYPSFMAKRFADFTVYRNRTLQKWHDKTKLASGKLGKASGFGAFERSILTQIDHILMDKERLLRRTQTKRSVYRVLGKPEPAVQPVPESLPGQPEILPEAPANAHLKDLDEEIFDDDDFYHQLLRELIERKTSSLDPNDQVAMGRQWLAIQKLRSKIHKKVDRKASKGRKLRFHVLSKLLSFMAPIDHTTMNDDARTELYRSLFGQLNPRDDSHGA", "length": 570, "header": "tr|A0AAA9TWF2-1|A0AAA9TWF2_BOVIN Isoform 1 of Apoptosis antagonizing transcription factor OS=Bos taurus OX=9913 GN=AATF PE=3 SV=2 CANONICAL=A0AAA9TWF2-1" }, "locus": { "chromosome": "19", "start_pos": 13420106, "end_pos": 13312414, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000114525.2", "url": "https://www.ensembl.org/id/ENSBTAT00000114525.2" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000102956.2", "url": "https://www.ensembl.org/id/ENSBTAP00000102956.2" } ] } }, { "isoform_ac": "E1BDL9-1", "url": "https://www.uniprot.org/uniprotkb/E1BDL9/entry", "sequence": { "sequence": "MTMAGPQSLALQLEQLLNPRPREADPEADPEEATAAKVIDRFDEGEDGEGDFQAVGSIRKLASASLLDTDKRYSGKTTSRKAWKEDHWEQTLSGSSDKEISDEDGSADGDSEGLGLEESDEEAMSAEDQEGGDEGDSSLAWKKRSGSHSQTSSGFSVQSISDFEKFTEGMDDLGSSEEEEEDEEESGMEEGESEEDSEDASEEDKAEARASEDDGVVMTFSEVRVSEEVEKGRAVKNQIGHKALKALLRSLVDLQEELLFQYPDTRYLVDGTKPKAESEEEISSDDEELVEKKKPQRRAPTKRKLETEDYPSFMAKRFADFTVYRNRTLQKWHDKTKLASGKLGKGFGAFERSILTQIDHILMDKERLLRRTQTKRSVYRVLGKPEPAVQPVPESLPGQPEILPEAPANAHLKDLDEEIFDDDDFYHQLLRELIERKTSSLDPNDQVAMGRQWLAIQKLRSKIHKKVDRKASKGRKLRFHVLSKLLSFMAPIDHTTMNDDARTELYRSLFGQLNPRDDSHGA", "length": 522, "header": "tr|E1BDL9-1|A0AAA9TWF2_BOVIN Computationally mapped isoform of Apoptosis antagonizing transcription factor OS=Bos taurus OX=9913 GN=AATF PE=3 SV=3 CANONICAL=A0AAA9TWF2-1" }, "locus": { "chromosome": "19", "start_pos": 13420106, "end_pos": 13312414, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000029234.7", "url": "https://www.ensembl.org/id/ENSBTAT00000029234.7" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000029234.6", "url": "https://www.ensembl.org/id/ENSBTAP00000029234.6" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [], "orthologs": [], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 5, "go_terms": [ { "name": "nucleus", "id": "GO:0005634", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005634", "evidence": [ { "database": "UniProtKB", "id": "A0AAA9TWF2", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TWF2" } ], "pmid": "" }, { "name": "cytoplasm", "id": "GO:0005737", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005737", "evidence": [ { "database": "UniProtKB", "id": "A0AAA9TWF2", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TWF2" } ], "pmid": "" }, { "name": "transcription regulator complex", "id": "GO:0005667", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005667", "evidence": [ { "database": "UniProtKB", "id": "A0AAA9TWF2", "url": 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"http://www.pantherdb.org/panther/family.do?clsAccession=PTHR46037", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00017", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00017", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF00018", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00018", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "A0AAA9T1L1", "url": "https://www.uniprot.org/uniprotkb/A0AAA9T1L1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0AAA9T1L1-1", "url": "https://www.uniprot.org/uniprotkb/A0AAA9T1L1-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "F6QN29", "url": "https://www.uniprot.org/uniprotkb/F6QN29", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "F6QN29-1", "url": "https://www.uniprot.org/uniprotkb/F6QN29-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MGSQPSRGKALPSPSFSPCVQGQNPEPMQAERSRAKAVALGSFPVGEQAELSLRLGEPLTIISEDGDWWTVLSDVSGREYSIPSIHVARIAHGWLYEGLSREKAEELLLLPGNHGGAFLIRESQTRRGRAGSQHGLSPTQSLSSSGCYSLSVRLSRPASWDRIKHYRIQRLDNGWLYISPRLTFPSLLALVDHYSELADDICCLLKEPCALRRAGPLPGKAIPPPVTVQATPLNWKELDSSLLFSEASAAGEESLLSEGLREALNSYISLTDDTSLDDAKAESRRRKGNQGCGT", "length": 294, "header": "tr|F6QN29-1|F6QN29_BOVIN Isoform 1 of Src like adaptor 2 OS=Bos taurus OX=9913 GN=SLA2 PE=4 SV=1 CANONICAL=F6QN29-1" }, "isoforms": [ { "isoform_ac": "A0AAA9T1L1-1", "url": "https://www.uniprot.org/uniprotkb/A0AAA9T1L1/entry", "sequence": { "sequence": "MGSQPSRGKALPSPSFSPCVQGQNPEPMQAERSRAKAVALGSFPVGEQAELSLRLGEPLTIISEDGDWWTVLSDVSGREYSIPSIHVARIAHGWLYEGLSREKAEELLLLPGNHGGAFLIRESQTRRGCYSLSVRLSRPASWDRIKHYRIQRLDNGWLYISPRLTFPSLLALVDHYSELADDICCLLKEPCALRRAGPLPGKAIPPPVTVQATPLNWKELDSSLLFSEASAAGEESLLSEGLREALNSYISLTDDTSLDDAKAESRRRKALRNHLTSSQRDDLAYNL", "length": 287, "header": "tr|A0AAA9T1L1-1|F6QN29_BOVIN Computationally mapped isoform of Src like adaptor 2 OS=Bos taurus OX=9913 GN=SLA2 PE=4 SV=1 CANONICAL=F6QN29-1" }, "locus": { "chromosome": "13", "start_pos": 65734441, "end_pos": 65713141, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000104673.1", "url": "https://www.ensembl.org/id/ENSBTAT00000104673.1" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000089550.1", "url": "https://www.ensembl.org/id/ENSBTAP00000089550.1" } ] } }, { "isoform_ac": "F6QN29-1", "url": "https://www.uniprot.org/uniprotkb/F6QN29/entry", "sequence": { "sequence": "MGSQPSRGKALPSPSFSPCVQGQNPEPMQAERSRAKAVALGSFPVGEQAELSLRLGEPLTIISEDGDWWTVLSDVSGREYSIPSIHVARIAHGWLYEGLSREKAEELLLLPGNHGGAFLIRESQTRRGRAGSQHGLSPTQSLSSSGCYSLSVRLSRPASWDRIKHYRIQRLDNGWLYISPRLTFPSLLALVDHYSELADDICCLLKEPCALRRAGPLPGKAIPPPVTVQATPLNWKELDSSLLFSEASAAGEESLLSEGLREALNSYISLTDDTSLDDAKAESRRRKGNQGCGT", "length": 294, "header": "tr|F6QN29-1|F6QN29_BOVIN Isoform 1 of Src like adaptor 2 OS=Bos taurus OX=9913 GN=SLA2 PE=4 SV=1 CANONICAL=F6QN29-1" }, "locus": { "chromosome": "13", "start_pos": 65734441, "end_pos": 65713322, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000026137.7", "url": "https://www.ensembl.org/id/ENSBTAT00000026137.7" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000026137.7", "url": "https://www.ensembl.org/id/ENSBTAP00000026137.7" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [], "orthologs": [], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 4, "go_terms": [ { "name": "plasma membrane", "id": "GO:0005886", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005886", "evidence": [ { "database": "UniProtKB", "id": "F6QN29", "url": "https://www.uniprot.org/uniprotkb/F6QN29" } ], "pmid": "" }, { "name": "endomembrane system", "id": "GO:0012505", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0012505", "evidence": [ { "database": "UniProtKB", "id": "F6QN29", "url": "https://www.uniprot.org/uniprotkb/F6QN29" } ], "pmid": "" }, { "name": "cytoplasmic vesicle", "id": "GO:0031410", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0031410", "evidence": [ { "database": "UniProtKB", "id": "F6QN29", "url": "https://www.uniprot.org/uniprotkb/F6QN29" } ], "pmid": "" }, { "name": "late endosome", "id": "GO:0005770", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005770", "evidence": [ { "database": "UniProtKB", "id": "F6QN29", "url": "https://www.uniprot.org/uniprotkb/F6QN29" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 4, "go_terms": [ { "name": "T cell activation", "id": "GO:0042110", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0042110", "evidence": [ { "database": "UniProtKB", "id": "F6QN29", "url": "https://www.uniprot.org/uniprotkb/F6QN29" } ], "pmid": "" }, { "name": "negative regulation of calcium-mediated signaling", "id": "GO:0050849", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0050849", "evidence": [ { "database": "UniProtKB", "id": "F6QN29", "url": "https://www.uniprot.org/uniprotkb/F6QN29" } ], "pmid": "" }, { "name": "negative regulation of transcription by RNA polymerase II", "id": "GO:0000122", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000122", "evidence": [ { "database": "UniProtKB", "id": "F6QN29", "url": "https://www.uniprot.org/uniprotkb/F6QN29" } ], "pmid": "" }, { "name": "negative regulation of T cell receptor signaling pathway", "id": "GO:0050860", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0050860", "evidence": [ { "database": "UniProtKB", "id": "F6QN29", "url": "https://www.uniprot.org/uniprotkb/F6QN29" } ], "pmid": "" } ] }, { "name": "Molecular Function", "total": 1, "go_terms": [ { "name": "signaling adaptor activity", "id": "GO:0035591", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0035591", "evidence": [ { "database": "UniProtKB", "id": "F6QN29", "url": "https://www.uniprot.org/uniprotkb/F6QN29" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [], "ptm_annotation": [], 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"field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ], "tool_support": { "graph_view": "yes" } }, { "uniprot_canonical_ac": "F6QY93-1", "uniprot_ac": "F6QY93", "uniprot_id": "F6QY93_BOVIN", "mass": { "chemical_mass": 36929.0, "monoisotopic_mass": 36929.0 }, "refseq": {}, "gene_names": [ { "name": "CDK3", "type": "recommended", "evidence": [ { "id": "F6QY93", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F6QY93" } ] } ], "protein_names": [ { "name": "cyclin-dependent kinase", "type": "recommended", "evidence": [ { "id": "F6QY93", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F6QY93/entry#names_and_taxonomy" } ] }, { "name": "2.7.11.22", "type": "synonym", "evidence": [ { "id": "F6QY93", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F6QY93/entry#names_and_taxonomy" } ] } ], "function": [], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Bos taurus", "taxid": 9913, "evidence": [ { "database": "UniProtKB", "id": "F6QY93", "url": "https://www.uniprot.org/uniprotkb/F6QY93" } ], "common_name": "Bovine", "glygen_name": "Bovine", "reference_species": "Bos taurus [9913]" } ], "gene": [ { "name": "CDK3", "url": "https://www.uniprot.org/uniprotkb/F6QY93", "locus": { "chromosome": "19", "start_pos": 55644968, "end_pos": 55649433, "strand": "+", "evidence": [ { "database": "Ensembl Gene", "id": "ENSBTAG00000010509", "url": "https://www.ensembl.org/id/ENSBTAG00000010509" } ] } } ], "crossref": [ { "id": "F6QY93", "url": "https://alphafold.ebi.ac.uk/entry/F6QY93", "database": "AlphaFoldDB", "categories": [] }, { "id": "cd07860", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd07860", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "IPR000719", "url": "https://www.ebi.ac.uk/interpro/entry/IPR000719", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR008271", "url": "https://www.ebi.ac.uk/interpro/entry/IPR008271", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR011009", "url": "https://www.ebi.ac.uk/interpro/entry/IPR011009", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR017441", "url": "https://www.ebi.ac.uk/interpro/entry/IPR017441", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR050108", "url": "https://www.ebi.ac.uk/interpro/entry/IPR050108", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "PTHR24056", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR24056", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR24056:SF462", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR24056:SF462", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00069", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00069", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "17989", "url": "https://www.rhea-db.org/rhea/17989", "database": "Rhea", "categories": [ "Enzyme and Pathway" ] }, { "id": "46608", "url": "https://www.rhea-db.org/rhea/46608", "database": "Rhea", "categories": [ "Enzyme and Pathway" ] }, { "id": "A0AAA9T237", "url": "https://www.uniprot.org/uniprotkb/A0AAA9T237", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0AAA9T237-1", "url": "https://www.uniprot.org/uniprotkb/A0AAA9T237-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "F6QY93", "url": "https://www.uniprot.org/uniprotkb/F6QY93", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "F6QY93-1", "url": "https://www.uniprot.org/uniprotkb/F6QY93-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MTGVLGTGGNAPGTLCFQGSSADMDMFQKVEKIGEGTYGVVYKARNKETGQLVALKKIRLDLETEGVPSTAIREISLLKELKHPNIVRLLDVVHSEKKLYLVFEFLSQDLKKYMDSTPASELPLHLVKRYLFQLLQGVNFCHTHRVIHRDLKPQNLLISELGTIKLADFGLARAFGVPLRTYTHEVVTLWYRAPEILLGCKFYSTAVDIWSIGCIFAEMVTRRALFPGDSEIDQLFRIFRTLGTPSEAMWPGVTQLPDYKGSFPKWTSKGLEEVVPNLEPEGQDLLLQLLQYDPSRRISAKAALAHPYFSSTETSSAPHQCMLERFCC", "length": 328, "header": "tr|F6QY93-1|F6QY93_BOVIN Isoform 1 of cyclin-dependent kinase OS=Bos taurus OX=9913 GN=CDK3 PE=3 SV=1 CANONICAL=F6QY93-1" }, "isoforms": [ { "isoform_ac": "A0AAA9T237-1", "url": "https://www.uniprot.org/uniprotkb/A0AAA9T237/entry", "sequence": { "sequence": "MDMFQKVEKIGEGTYGVVYKARNKETGQLVALKKIRLDLLLDVVHSEKKLYLVFEFLSQDLKKYMDSTPASELPLHLVKRYLFQLLQGVNFCHTHRVIHRDLKPQNLLISELGTIKLADFGLARAFGVPLRTYTHEVVTLWYRAPEILLGCKFYSTAVDIWSIGCIFAEMVTRRALFPGDSEIDQLFRIFRTLGTPSEAMWPGVTQLPDYKGSFPKWTSKGLEEVVPNLEPEGQDLLLQLLQYDPSRRISAKAALAHPYFSSTETSSAPHQCMLERFCC", "length": 279, "header": "tr|A0AAA9T237-1|F6QY93_BOVIN Computationally mapped isoform of cyclin-dependent kinase OS=Bos taurus OX=9913 GN=CDK3 PE=3 SV=1 CANONICAL=F6QY93-1" }, "locus": { "chromosome": "19", "start_pos": 55648599, "end_pos": 55645570, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000107473.1", "url": "https://www.ensembl.org/id/ENSBTAT00000107473.1" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000090692.1", "url": "https://www.ensembl.org/id/ENSBTAP00000090692.1" } ] } }, { "isoform_ac": "F6QY93-1", "url": "https://www.uniprot.org/uniprotkb/F6QY93/entry", "sequence": { "sequence": "MTGVLGTGGNAPGTLCFQGSSADMDMFQKVEKIGEGTYGVVYKARNKETGQLVALKKIRLDLETEGVPSTAIREISLLKELKHPNIVRLLDVVHSEKKLYLVFEFLSQDLKKYMDSTPASELPLHLVKRYLFQLLQGVNFCHTHRVIHRDLKPQNLLISELGTIKLADFGLARAFGVPLRTYTHEVVTLWYRAPEILLGCKFYSTAVDIWSIGCIFAEMVTRRALFPGDSEIDQLFRIFRTLGTPSEAMWPGVTQLPDYKGSFPKWTSKGLEEVVPNLEPEGQDLLLQLLQYDPSRRISAKAALAHPYFSSTETSSAPHQCMLERFCC", "length": 328, "header": "tr|F6QY93-1|F6QY93_BOVIN Isoform 1 of cyclin-dependent kinase OS=Bos taurus OX=9913 GN=CDK3 PE=3 SV=1 CANONICAL=F6QY93-1" }, "locus": { "chromosome": "19", "start_pos": 55648843, "end_pos": 55645570, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000013885.6", "url": "https://www.ensembl.org/id/ENSBTAT00000013885.6" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000013885.5", "url": "https://www.ensembl.org/id/ENSBTAP00000013885.5" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [ "enzyme" ], "publication": [], "pathway": [], "orthologs": [], "go_annotation": { "categories": [ { "name": "Molecular Function", "total": 2, "go_terms": [ { "name": "ATP binding", "id": "GO:0005524", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005524", "evidence": [ { "database": "UniProtKB", "id": "F6QY93", "url": "https://www.uniprot.org/uniprotkb/F6QY93" } ], "pmid": "" }, { "name": "cyclin-dependent protein serine/threonine kinase activity", "id": "GO:0004693", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0004693", "evidence": [ { "database": "UniProtKB", "id": "F6QY93", "url": "https://www.uniprot.org/uniprotkb/F6QY93" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 3, "go_terms": [ { "name": "cell division", "id": "GO:0051301", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0051301", "evidence": [ { "database": "UniProtKB", "id": "F6QY93", "url": "https://www.uniprot.org/uniprotkb/F6QY93" } ], "pmid": "" }, { "name": "negative regulation of Notch signaling pathway", "id": "GO:0045746", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0045746", "evidence": [ { "database": "UniProtKB", "id": "F6QY93", "url": "https://www.uniprot.org/uniprotkb/F6QY93" } ], "pmid": "" }, { "name": "G0 to G1 transition", "id": "GO:0045023", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0045023", "evidence": [ { "database": "UniProtKB", "id": "F6QY93", "url": "https://www.uniprot.org/uniprotkb/F6QY93" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [], "ptm_annotation": [], "interactions": [], "reactions": [ { "id": "17989", "name": "", "equation": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+)", "summary": "", "cellular_location": "", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [ "G5E5K2-1", "V6F977-1", "A0A3Q1MRW3-1", "A0A3Q1N860-1", "E1BI01-1", "F6RG88-1", "A0AAA9T8T9-1", "A0AAA9U1R3-1", "A7E3X2-1", "A0AAA9U1M9-1", "E1B754-1", "A0AAA9T7L6-1", "A0A3Q1M9F0-1", "A0ABI0P3P6-1", "E1BNH0-1", "A0AAA9TMV7-1", "A0AAA9T2F0-1", "A0AAA9S663-1", "A0AAA9U1A4-1", "F1MKY9-1", 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"id": "A0A3Q1MD82", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1MD82" } ] } ] }, { "uniprot_ac": "A0A3Q1MEZ6", "gene_name": "MTOR", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A3Q1MEZ6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1MEZ6" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A3Q1MEZ6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1MEZ6" } ] } ] }, { "uniprot_ac": "A0A3Q1MHH5", "gene_name": "MAP3K9", "activity": [ { "ec_number": "2.7.11.25", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A3Q1MHH5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1MHH5" } ] }, { "ec_number": "2.7.11.25", "activity": "", "evidence": [ { "id": "A0A3Q1MHH5", "database": "UniProtKB", "url": 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"ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A3Q1MLK5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1MLK5" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A3Q1MLK5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1MLK5" } ] } ] }, { "uniprot_ac": "A0A3Q1MNB4", "gene_name": "STK32A", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A3Q1MNB4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1MNB4" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A3Q1MNB4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1MNB4" } ] } ] }, { "uniprot_ac": "A0A3Q1MRR6", "gene_name": "PRKCD", "activity": [ { "ec_number": "2.7.11.13", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A3Q1MRR6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1MRR6" } ] }, { "ec_number": "2.7.11.13", "activity": "", "evidence": [ { "id": "A0A3Q1MRR6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1MRR6" } ] } ] }, { "uniprot_ac": "A0A3Q1MRW3", "gene_name": "SNRK", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A3Q1MRW3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1MRW3" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A3Q1MRW3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1MRW3" } ] } ] }, { "uniprot_ac": "A0A3Q1MS69", "gene_name": "NEK2", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": 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"https://www.uniprot.org/uniprotkb/A0A3Q1MW77" } ] }, { "ec_number": "2.7.11.39", "activity": "", "evidence": [ { "id": "A0A3Q1MW77", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1MW77" } ] } ] }, { "uniprot_ac": "A0A3Q1MXI5", "gene_name": "DAPK1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A3Q1MXI5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1MXI5" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A3Q1MXI5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1MXI5" } ] } ] }, { "uniprot_ac": "A0A3Q1N4A7", "gene_name": "CIT", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A3Q1N4A7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1N4A7" } ] }, { 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}, { "uniprot_ac": "A0A3S5ZPR2", "gene_name": "MELK", "activity": [ { "ec_number": "2.7.10.2", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A3S5ZPR2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3S5ZPR2" } ] }, { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A3S5ZPR2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3S5ZPR2" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A3S5ZPR2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3S5ZPR2" } ] }, { "ec_number": "2.7.10.2", "activity": "", "evidence": [ { "id": "A0A3S5ZPR2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3S5ZPR2" } ] } ] }, { "uniprot_ac": "A0AAA9RSJ2", "gene_name": "MKNK2", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0AAA9RSJ2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9RSJ2" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0AAA9RSJ2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9RSJ2" } ] } ] }, { "uniprot_ac": "A0AAA9RSQ6", "gene_name": "TRPM6", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0AAA9RSQ6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9RSQ6" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0AAA9RSQ6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9RSQ6" } ] } ] }, { "uniprot_ac": "A0AAA9RTJ4", "gene_name": "PIKFYVE", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0AAA9RTJ4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9RTJ4" } ] }, { "ec_number": "2.7.1.150", "activity": "a 1,2-diacyl-sn-glycero-3-phospho-(1D-myo-inositol-3-phosphate) + ATP = a 1,2-diacyl-sn-glycero-3-phospho-(1D-myo-inositol-3,5-bisphosphate) + ADP + H(+).", "evidence": [ { "id": "A0AAA9RTJ4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9RTJ4" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0AAA9RTJ4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9RTJ4" } ] }, { "ec_number": "2.7.1.150", "activity": "", "evidence": [ { "id": "A0AAA9RTJ4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9RTJ4" } ] } ] }, { "uniprot_ac": "A0AAA9RVB1", "gene_name": "TAOK2", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0AAA9RVB1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9RVB1" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0AAA9RVB1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9RVB1" } ] } ] }, { "uniprot_ac": "A0AAA9RW51", "gene_name": "AATK", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0AAA9RW51", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9RW51" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0AAA9RW51", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9RW51" } ] } ] }, { "uniprot_ac": "A0AAA9RWB8", "gene_name": "TRIO", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0AAA9RWB8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9RWB8" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0AAA9RWB8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9RWB8" } ] } ] }, { "uniprot_ac": "A0AAA9RWC6", "gene_name": "CHEK2", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0AAA9RWC6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9RWC6" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0AAA9RWC6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9RWC6" } ] } ] }, { "uniprot_ac": "A0AAA9S2N3", "gene_name": "CDKL4", "activity": [ { "ec_number": "2.7.11.22", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0AAA9S2N3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9S2N3" } ] }, { "ec_number": "2.7.11.22", "activity": "", "evidence": [ { "id": "A0AAA9S2N3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9S2N3" } ] } ] }, { "uniprot_ac": "A0AAA9S472", "gene_name": "MAPK8", "activity": [ { "ec_number": "2.7.11.24", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0AAA9S472", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9S472" } ] }, { "ec_number": "2.7.11.24", "activity": "", "evidence": [ { "id": "A0AAA9S472", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9S472" } ] } ] }, { "uniprot_ac": "A0AAA9S4Z4", "gene_name": "AKT1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0AAA9S4Z4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9S4Z4" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0AAA9S4Z4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9S4Z4" } ] } ] }, { "uniprot_ac": "A0AAA9S5X7", "gene_name": "AURKB", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0AAA9S5X7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9S5X7" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0AAA9S5X7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9S5X7" } ] } ] }, { "uniprot_ac": "A0AAA9S663", "gene_name": "PDPK1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0AAA9S663", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9S663" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0AAA9S663", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9S663" } ] } ] }, { "uniprot_ac": "A0AAA9S954", "gene_name": "CAMKK1", "activity": [ { "ec_number": "2.7.11.17", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0AAA9S954", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9S954" } ] }, { "ec_number": "2.7.11.17", "activity": "", "evidence": [ { "id": "A0AAA9S954", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9S954" } ] } ] }, { "uniprot_ac": "A0AAA9S9A9", "gene_name": "NEK11", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0AAA9S9A9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9S9A9" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0AAA9S9A9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9S9A9" } ] } ] }, { "uniprot_ac": "A0AAA9SG01", "gene_name": "ERN1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0AAA9SG01", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9SG01" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0AAA9SG01", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9SG01" } ] } ] }, { "uniprot_ac": "A0AAA9SGM8", "gene_name": "MKNK1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0AAA9SGM8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9SGM8" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0AAA9SGM8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9SGM8" } ] } ] }, { "uniprot_ac": "A0AAA9SH90", "gene_name": "DAPK2", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0AAA9SH90", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9SH90" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0AAA9SH90", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9SH90" } ] } ] }, { "uniprot_ac": "A0AAA9SIK7", "gene_name": "NEK10", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0AAA9SIK7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9SIK7" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0AAA9SIK7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9SIK7" } ] } ] }, { "uniprot_ac": "A0AAA9SJ92", "gene_name": "RPS6KA1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0AAA9SJ92", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9SJ92" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0AAA9SJ92", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9SJ92" } ] } ] }, { "uniprot_ac": "A0AAA9SJA3", "gene_name": "TTBK2", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0AAA9SJA3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9SJA3" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0AAA9SJA3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9SJA3" } ] } ] }, { "uniprot_ac": "A0AAA9SJQ0", "gene_name": "RPS6KA4", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0AAA9SJQ0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9SJQ0" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0AAA9SJQ0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9SJQ0" } ] } ] }, { "uniprot_ac": "A0AAA9SK35", "gene_name": "PRKG2", "activity": [ { "ec_number": "2.7.11.12", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0AAA9SK35", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9SK35" } ] }, { "ec_number": "2.7.11.12", "activity": "", "evidence": [ { "id": "A0AAA9SK35", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9SK35" } ] } ] }, { "uniprot_ac": "A0AAA9SKK8", "gene_name": "MAP3K4", "activity": [ { "ec_number": "2.7.11.25", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0AAA9SKK8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9SKK8" } ] }, { "ec_number": "2.7.11.25", "activity": "", "evidence": [ { "id": "A0AAA9SKK8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9SKK8" } ] } ] }, { "uniprot_ac": "A0AAA9SLY1", "gene_name": "NEK5", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0AAA9SLY1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9SLY1" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0AAA9SLY1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9SLY1" } ] } ] }, { "uniprot_ac": "A0AAA9SMH0", "gene_name": "DCLK3", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0AAA9SMH0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9SMH0" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0AAA9SMH0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9SMH0" } ] } ] }, { "uniprot_ac": "A0AAA9SMT9", "gene_name": "MAP3K12", "activity": [ { "ec_number": "2.7.11.25", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0AAA9SMT9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9SMT9" } ] }, { "ec_number": "2.7.11.25", "activity": "", "evidence": [ { "id": "A0AAA9SMT9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9SMT9" } ] } ] }, { "uniprot_ac": "A0AAA9SNP6", "gene_name": "MOS", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0AAA9SNP6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9SNP6" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0AAA9SNP6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9SNP6" } ] } ] }, { "uniprot_ac": "A0AAA9SU81", "gene_name": "PRKAA2", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0AAA9SU81", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9SU81" } ] }, { "ec_number": "2.7.11.31", "activity": "L-seryl-[acetyl-CoA carboxylase] + ATP = O-phospho-L-seryl-[acetyl-CoA carboxylase] + ADP + H(+).", "evidence": [ { "id": "A0AAA9SU81", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9SU81" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0AAA9SU81", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9SU81" } ] }, { "ec_number": "2.7.11.31", "activity": "", "evidence": [ { "id": "A0AAA9SU81", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9SU81" } ] } ] }, { "uniprot_ac": "A0AAA9SVM5", "gene_name": "MAP3K3", "activity": [ { "ec_number": "2.7.11.25", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0AAA9SVM5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9SVM5" } ] }, { "ec_number": "2.7.11.25", "activity": "", "evidence": [ { "id": "A0AAA9SVM5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9SVM5" } ] } ] }, { "uniprot_ac": "A0AAA9SWA1", "gene_name": "STK26", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0AAA9SWA1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9SWA1" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0AAA9SWA1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9SWA1" } ] } ] }, { "uniprot_ac": "A0AAA9SX77", "gene_name": "CDK14", "activity": [ { "ec_number": "2.7.11.22", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0AAA9SX77", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9SX77" } ] }, { "ec_number": "2.7.11.22", "activity": "", "evidence": [ { "id": "A0AAA9SX77", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9SX77" } ] } ] }, { "uniprot_ac": "A0AAA9SXE3", "gene_name": "MAP3K6", "activity": [ { "ec_number": "2.7.11.25", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0AAA9SXE3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9SXE3" } ] }, { "ec_number": "2.7.11.25", "activity": "", "evidence": [ { "id": "A0AAA9SXE3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9SXE3" } ] } ] }, { "uniprot_ac": "A0AAA9SYW5", "gene_name": "NEK3", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0AAA9SYW5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9SYW5" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0AAA9SYW5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9SYW5" } ] } ] }, { "uniprot_ac": "A0AAA9T042", "gene_name": "DYRK4", "activity": [ { "ec_number": "2.7.12.1", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0AAA9T042", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9T042" } ] }, { "ec_number": "2.7.12.1", "activity": "", "evidence": [ { "id": "A0AAA9T042", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9T042" } ] } ] }, { "uniprot_ac": "A0AAA9T2F0", "gene_name": "BRAF", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0AAA9T2F0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9T2F0" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0AAA9T2F0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9T2F0" } ] } ] }, { "uniprot_ac": "A0AAA9T3H7", "gene_name": "TNK1", "activity": [ { "ec_number": "2.7.10.2", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0AAA9T3H7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9T3H7" } ] }, { "ec_number": "2.7.10.2", "activity": "", "evidence": [ { "id": "A0AAA9T3H7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9T3H7" } ] } ] }, { "uniprot_ac": "A0AAA9T3K7", "gene_name": "WNK3", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0AAA9T3K7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9T3K7" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0AAA9T3K7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9T3K7" } ] } ] }, { "uniprot_ac": "A0AAA9T584", "gene_name": "CSNK1G3", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0AAA9T584", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9T584" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0AAA9T584", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9T584" } ] } ] }, { "uniprot_ac": "A0AAA9T593", "gene_name": "SRPK1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0AAA9T593", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9T593" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0AAA9T593", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9T593" } ] } ] }, { "uniprot_ac": "A0AAA9T5C9", "gene_name": "MAPK1", "activity": [ { "ec_number": "2.7.11.24", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0AAA9T5C9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9T5C9" } ] }, { "ec_number": "2.7.11.24", "activity": "", "evidence": [ { "id": "A0AAA9T5C9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9T5C9" } ] } ] }, { "uniprot_ac": "A0AAA9T7I8", "gene_name": "TSSK2", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0AAA9T7I8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9T7I8" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0AAA9T7I8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9T7I8" } ] } ] }, { "uniprot_ac": "A0AAA9T7L6", "gene_name": "RPS6KC1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0AAA9T7L6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9T7L6" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0AAA9T7L6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9T7L6" } ] } ] }, { "uniprot_ac": "A0AAA9T7Z7", "gene_name": "RPS6KA5", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0AAA9T7Z7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9T7Z7" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0AAA9T7Z7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9T7Z7" } ] } ] }, { "uniprot_ac": "A0AAA9T8T9", "gene_name": "MARK2", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0AAA9T8T9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9T8T9" } ] }, { "ec_number": "2.7.11.26", "activity": "L-seryl-[tau protein] + ATP = O-phospho-L-seryl-[tau protein] + ADP + H(+).", "evidence": [ { "id": "A0AAA9T8T9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9T8T9" } ] }, { "ec_number": "2.7.11.26", "activity": "", "evidence": [ { "id": "A0AAA9T8T9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9T8T9" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0AAA9T8T9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9T8T9" } ] } ] }, { "uniprot_ac": "A0AAA9T8Z3", "gene_name": "STK32C", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0AAA9T8Z3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9T8Z3" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0AAA9T8Z3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9T8Z3" } ] } ] }, { "uniprot_ac": "A0AAA9T940", "gene_name": "PLK2", "activity": [ { "ec_number": "2.7.11.21", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0AAA9T940", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9T940" } ] }, { "ec_number": "2.7.11.21", "activity": "", "evidence": [ { "id": "A0AAA9T940", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9T940" } ] } ] }, { "uniprot_ac": "A0AAA9TCI9", "gene_name": "MOK", "activity": [ { "ec_number": "2.7.11.22", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0AAA9TCI9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TCI9" } ] }, { "ec_number": "2.7.11.22", "activity": "", "evidence": [ { "id": "A0AAA9TCI9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TCI9" } ] } ] }, { "uniprot_ac": "A0AAA9TD48", "gene_name": "DYRK1B", "activity": [ { "ec_number": "2.7.12.1", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0AAA9TD48", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TD48" } ] }, { "ec_number": "2.7.12.1", "activity": "", "evidence": [ { "id": "A0AAA9TD48", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TD48" } ] } ] }, { "uniprot_ac": "A0AAA9TDL1", "gene_name": "SBK1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0AAA9TDL1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TDL1" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0AAA9TDL1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TDL1" } ] } ] }, { "uniprot_ac": "A0AAA9TJD5", "gene_name": "", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0AAA9TJD5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TJD5" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0AAA9TJD5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TJD5" } ] } ] }, { "uniprot_ac": "A0AAA9TLV0", "gene_name": "STK32B", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0AAA9TLV0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TLV0" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0AAA9TLV0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TLV0" } ] } ] }, { "uniprot_ac": "A0AAA9TMV7", "gene_name": "SMG1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0AAA9TMV7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TMV7" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0AAA9TMV7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TMV7" } ] } ] }, { "uniprot_ac": "A0AAA9TNE6", "gene_name": "TLK2", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0AAA9TNE6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TNE6" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0AAA9TNE6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TNE6" } ] } ] }, { "uniprot_ac": "A0AAA9TNL3", "gene_name": "SLK", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0AAA9TNL3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TNL3" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0AAA9TNL3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TNL3" } ] } ] }, { "uniprot_ac": "A0AAA9TP92", "gene_name": "CAMK1", "activity": [ { "ec_number": "2.7.11.17", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0AAA9TP92", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TP92" } ] }, { "ec_number": "2.7.11.17", "activity": "", "evidence": [ { "id": "A0AAA9TP92", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TP92" } ] } ] }, { "uniprot_ac": "A0AAA9TU12", "gene_name": "PRKCQ", "activity": [ { "ec_number": "2.7.11.13", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0AAA9TU12", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TU12" } ] }, { "ec_number": "2.7.11.13", "activity": "", "evidence": [ { "id": "A0AAA9TU12", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TU12" } ] } ] }, { "uniprot_ac": "A0AAA9TVT5", "gene_name": "CASK", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0AAA9TVT5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TVT5" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0AAA9TVT5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TVT5" } ] } ] }, { "uniprot_ac": "A0AAA9TWW0", "gene_name": "TBK1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0AAA9TWW0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TWW0" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0AAA9TWW0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TWW0" } ] } ] }, { "uniprot_ac": "A0AAA9U136", "gene_name": "PRKD2", "activity": [ { "ec_number": "2.7.11.13", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0AAA9U136", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9U136" } ] }, { "ec_number": "2.7.11.13", "activity": "", "evidence": [ { "id": "A0AAA9U136", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9U136" } ] } ] }, { "uniprot_ac": "A0AAA9U1A4", "gene_name": "NUAK2", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0AAA9U1A4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9U1A4" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0AAA9U1A4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9U1A4" } ] } ] }, { "uniprot_ac": "A0AAA9U1M9", "gene_name": "DMPK", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0AAA9U1M9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9U1M9" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0AAA9U1M9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9U1M9" } ] } ] }, { "uniprot_ac": "A0AAA9U1R3", "gene_name": "DCLK2", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0AAA9U1R3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9U1R3" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0AAA9U1R3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9U1R3" } ] } ] }, { "uniprot_ac": "A0AAF6DLR2", "gene_name": "CDK18", "activity": [ { "ec_number": "2.7.11.22", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0AAF6DLR2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAF6DLR2" } ] }, { "ec_number": "2.7.11.22", "activity": "", "evidence": [ { "id": "A0AAF6DLR2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAF6DLR2" } ] } ] }, { "uniprot_ac": "A0AAF6DMH7", "gene_name": "RIPK1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0AAF6DMH7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAF6DMH7" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0AAF6DMH7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAF6DMH7" } ] } ] }, { "uniprot_ac": "A0AAF6YHL8", "gene_name": "MAPK7", "activity": [ { "ec_number": "2.7.11.24", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0AAF6YHL8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAF6YHL8" } ] }, { "ec_number": "2.7.11.24", "activity": "", "evidence": [ { "id": "A0AAF6YHL8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAF6YHL8" } ] } ] }, { "uniprot_ac": "A0AAF6YMX3", "gene_name": "CDK9", "activity": [ { "ec_number": "2.7.11.22", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0AAF6YMX3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAF6YMX3" } ] }, { "ec_number": "2.7.11.23", "activity": "[DNA-directed RNA polymerase] + ATP = phospho-[DNA-directed RNA polymerase] + ADP + H(+).", "evidence": [ { "id": "A0AAF6YMX3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAF6YMX3" } ] }, { "ec_number": "2.7.11.22", "activity": "", "evidence": [ { "id": "A0AAF6YMX3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAF6YMX3" } ] }, { "ec_number": "2.7.11.23", "activity": "", "evidence": [ { "id": "A0AAF6YMX3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAF6YMX3" } ] } ] }, { "uniprot_ac": "A0AAF6Z257", "gene_name": "IRAK1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0AAF6Z257", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAF6Z257" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0AAF6Z257", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAF6Z257" } ] } ] }, { "uniprot_ac": "A0ABI0NJ75", "gene_name": "PAK6", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0ABI0NJ75", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NJ75" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0ABI0NJ75", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NJ75" } ] } ] }, { "uniprot_ac": "A0ABI0NM98", "gene_name": "KALRN", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0ABI0NM98", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NM98" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0ABI0NM98", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NM98" } ] } ] }, { "uniprot_ac": "A0ABI0NMT8", "gene_name": "PIK3CG", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0ABI0NMT8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NMT8" } ] }, { "ec_number": "2.7.1.153", "activity": "a 1,2-diacyl-sn-glycero-3-phospho-(1D-myo-inositol-4,5-bisphosphate) + ATP = a 1,2-diacyl-sn-glycero-3-phospho-(1D-myo-inositol-3,4,5-trisphosphate) + ADP + H(+).", "evidence": [ { "id": "A0ABI0NMT8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NMT8" } ] }, { "ec_number": "2.7.1.137", "activity": "a 1,2-diacyl-sn-glycero-3-phospho-(1D-myo-inositol) + ATP = a 1,2-diacyl-sn-glycero-3-phospho-(1D-myo-inositol-3-phosphate) + ADP + H(+).", "evidence": [ { "id": "A0ABI0NMT8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NMT8" } ] }, { "ec_number": "2.7.1.154", "activity": "a 1,2-diacyl-sn-glycero-3-phospho-(1D-myo-inositol 4-phosphate) + ATP = a 1,2-diacyl-sn-glycero-3-phospho-(1D-myo-inositol-3,4-bisphosphate) + ADP + H(+).", "evidence": [ { "id": "A0ABI0NMT8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NMT8" } ] }, { "ec_number": "2.7.1.153", "activity": "", "evidence": [ { "id": "A0ABI0NMT8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NMT8" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0ABI0NMT8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NMT8" } ] }, { "ec_number": "2.7.1.137", "activity": "", "evidence": [ { "id": "A0ABI0NMT8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NMT8" } ] }, { "ec_number": "2.7.1.154", "activity": "", "evidence": [ { "id": "A0ABI0NMT8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NMT8" } ] } ] }, { "uniprot_ac": "A0ABI0NQQ4", "gene_name": "PRKAA1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0ABI0NQQ4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NQQ4" } ] }, { "ec_number": "2.7.11.26", "activity": "L-seryl-[tau protein] + ATP = O-phospho-L-seryl-[tau protein] + ADP + H(+).", "evidence": [ { "id": "A0ABI0NQQ4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NQQ4" } ] }, { "ec_number": "2.7.11.31", "activity": "L-seryl-[acetyl-CoA carboxylase] + ATP = O-phospho-L-seryl-[acetyl-CoA carboxylase] + ADP + H(+).", "evidence": [ { "id": "A0ABI0NQQ4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NQQ4" } ] }, { "ec_number": "2.7.11.26", "activity": "", "evidence": [ { "id": "A0ABI0NQQ4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NQQ4" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0ABI0NQQ4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NQQ4" } ] }, { "ec_number": "2.7.11.31", "activity": "", "evidence": [ { "id": "A0ABI0NQQ4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NQQ4" } ] } ] }, { "uniprot_ac": "A0ABI0NRQ5", "gene_name": "LOC101905399", "activity": [ { "ec_number": "2.7.12.2", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0ABI0NRQ5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NRQ5" } ] }, { "ec_number": "2.7.12.2", "activity": "", "evidence": [ { "id": "A0ABI0NRQ5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NRQ5" } ] } ] }, { "uniprot_ac": "A0ABI0NS30", "gene_name": "PRKCA", "activity": [ { "ec_number": "2.7.11.13", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0ABI0NS30", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NS30" } ] }, { "ec_number": "2.7.11.13", "activity": "", "evidence": [ { "id": "A0ABI0NS30", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NS30" } ] } ] }, { "uniprot_ac": "A0ABI0NV47", "gene_name": "DCLK1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0ABI0NV47", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NV47" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0ABI0NV47", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NV47" } ] } ] }, { "uniprot_ac": "A0ABI0P0X3", "gene_name": "", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0ABI0P0X3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0ABI0P0X3" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0ABI0P0X3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0ABI0P0X3" } ] } ] }, { "uniprot_ac": "A0ABI0P2C0", "gene_name": "TSSK5", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0ABI0P2C0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0ABI0P2C0" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0ABI0P2C0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0ABI0P2C0" } ] } ] }, { "uniprot_ac": "A0ABI0P3N8", "gene_name": "", "activity": [ { "ec_number": "2.7.11.22", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0ABI0P3N8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0ABI0P3N8" } ] }, { "ec_number": "2.7.11.22", "activity": "", "evidence": [ { "id": "A0ABI0P3N8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0ABI0P3N8" } ] } ] }, { "uniprot_ac": "A0ABI0P3P6", "gene_name": "MAST4", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0ABI0P3P6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0ABI0P3P6" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0ABI0P3P6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0ABI0P3P6" } ] } ] }, { "uniprot_ac": "A0ABI0P443", "gene_name": "SGK2", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0ABI0P443", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0ABI0P443" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0ABI0P443", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0ABI0P443" } ] } ] }, { "uniprot_ac": "A1A4I4", "gene_name": "PKN1", "activity": [ { "ec_number": "2.7.11.13", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A1A4I4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A1A4I4" } ] }, { "ec_number": "2.7.11.13", "activity": "", "evidence": [ { "id": "A1A4I4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A1A4I4" } ] } ] }, { "uniprot_ac": "A2VDU3", "gene_name": "MAP3K7", "activity": [ { "ec_number": "2.7.11.25", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A2VDU3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A2VDU3" } ] }, { "ec_number": "2.7.11.25", "activity": "", "evidence": [ { "id": "A2VDU3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A2VDU3" } ] } ] }, { "uniprot_ac": "A2VDV2", "gene_name": "STK38", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A2VDV2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A2VDV2" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A2VDV2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A2VDV2" } ] } ] }, { "uniprot_ac": "A2VDZ4", "gene_name": "PLK4", "activity": [ { "ec_number": "2.7.11.21", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A2VDZ4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A2VDZ4" } ] }, { "ec_number": "2.7.11.21", "activity": "", "evidence": [ { "id": "A2VDZ4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A2VDZ4" } ] } ] }, { "uniprot_ac": "A5D791", "gene_name": "EIF2AK3", "activity": [ { "ec_number": "2.7.10.2", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "A5D791", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A5D791" } ] }, { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A5D791", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A5D791" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A5D791", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A5D791" } ] } ] }, { "uniprot_ac": "A5PKJ4", "gene_name": "MAPK7", "activity": [ { "ec_number": "2.7.11.24", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A5PKJ4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A5PKJ4" } ] }, { "ec_number": "2.7.11.24", "activity": "", "evidence": [ { "id": "A5PKJ4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A5PKJ4" } ] } ] }, { "uniprot_ac": "A7E3S4", "gene_name": "RAF1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A7E3S4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A7E3S4" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A7E3S4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A7E3S4" } ] } ] }, { "uniprot_ac": "A7E3X2", "gene_name": "CSNK1G1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A7E3X2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A7E3X2" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A7E3X2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A7E3X2" } ] } ] }, { "uniprot_ac": "A7MB74", "gene_name": "SGK1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A7MB74", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A7MB74" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A7MB74", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A7MB74" } ] } ] }, { "uniprot_ac": "A7MBB4", "gene_name": "MAP3K13", "activity": [ { "ec_number": "2.7.11.25", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A7MBB4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A7MBB4" } ] }, { "ec_number": "2.7.11.25", "activity": "", "evidence": [ { "id": "A7MBB4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A7MBB4" } ] } ] }, { "uniprot_ac": "E1B754", "gene_name": "MAST2", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "E1B754", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1B754" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "E1B754", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1B754" } ] } ] }, { "uniprot_ac": "E1B793", "gene_name": "STK36", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "E1B793", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1B793" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "E1B793", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1B793" } ] } ] }, { "uniprot_ac": "E1B7H4", "gene_name": "MAP3K10", "activity": [ { "ec_number": "2.7.11.25", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "E1B7H4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1B7H4" } ] }, { "ec_number": "2.7.11.25", "activity": "", "evidence": [ { "id": "E1B7H4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1B7H4" } ] } ] }, { "uniprot_ac": "E1B7L9", "gene_name": "PRKD3", "activity": [ { "ec_number": "2.7.11.13", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "E1B7L9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1B7L9" } ] }, { "ec_number": "2.7.11.13", "activity": "", "evidence": [ { "id": "E1B7L9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1B7L9" } ] } ] }, { "uniprot_ac": "E1B827", "gene_name": "NEK8", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "E1B827", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1B827" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "E1B827", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1B827" } ] } ] }, { "uniprot_ac": "E1B887", "gene_name": "RIOK1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "E1B887", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1B887" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "E1B887", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1B887" } ] } ] }, { "uniprot_ac": "E1B8J7", "gene_name": "ERN2", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "E1B8J7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1B8J7" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "E1B8J7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1B8J7" } ] } ] }, { "uniprot_ac": "E1B8P9", "gene_name": "MAPK3", "activity": [ { "ec_number": "2.7.11.24", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "E1B8P9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1B8P9" } ] }, { "ec_number": "2.7.11.24", "activity": "", "evidence": [ { "id": "E1B8P9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1B8P9" } ] } ] }, { "uniprot_ac": "E1B902", "gene_name": "MAP4K2", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "E1B902", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1B902" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "E1B902", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1B902" } ] } ] }, { "uniprot_ac": "E1B9B6", "gene_name": "NUAK1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "E1B9B6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1B9B6" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "E1B9B6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1B9B6" } ] } ] }, { "uniprot_ac": "E1B9F9", "gene_name": "LATS2", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "E1B9F9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1B9F9" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "E1B9F9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1B9F9" } ] } ] }, { "uniprot_ac": "E1B9Q2", "gene_name": "CLK2", "activity": [ { "ec_number": "2.7.12.1", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "E1B9Q2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1B9Q2" } ] }, { "ec_number": "2.7.12.1", "activity": "", "evidence": [ { "id": "E1B9Q2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1B9Q2" } ] } ] }, { "uniprot_ac": "E1BAL6", "gene_name": "EIF2AK4", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "E1BAL6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BAL6" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "E1BAL6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BAL6" } ] } ] }, { "uniprot_ac": "E1BB49", "gene_name": "HIPK4", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "E1BB49", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BB49" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "E1BB49", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BB49" } ] } ] }, { "uniprot_ac": "E1BB50", "gene_name": "CDK12", "activity": [ { "ec_number": "2.7.11.22", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "E1BB50", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BB50" } ] }, { "ec_number": "2.7.11.23", "activity": "[DNA-directed RNA polymerase] + ATP = phospho-[DNA-directed RNA polymerase] + ADP + H(+).", "evidence": [ { "id": "E1BB50", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BB50" } ] }, { "ec_number": "2.7.11.23", "activity": "", "evidence": [ { "id": "E1BB50", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BB50" } ] }, { "ec_number": "2.7.11.22", "activity": "", "evidence": [ { "id": "E1BB50", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BB50" } ] } ] }, { "uniprot_ac": "E1BB52", "gene_name": "CDK13", "activity": [ { "ec_number": "2.7.11.22", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "E1BB52", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BB52" } ] }, { "ec_number": "2.7.11.23", "activity": "[DNA-directed RNA polymerase] + ATP = phospho-[DNA-directed RNA polymerase] + ADP + H(+).", "evidence": [ { "id": "E1BB52", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BB52" } ] }, { "ec_number": "2.7.11.23", "activity": "", "evidence": [ { "id": "E1BB52", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BB52" } ] }, { "ec_number": "2.7.11.22", "activity": "", "evidence": [ { "id": "E1BB52", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BB52" } ] } ] }, { "uniprot_ac": "E1BBM3", "gene_name": "NEK1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "E1BBM3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BBM3" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "E1BBM3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BBM3" } ] } ] }, { "uniprot_ac": "E1BC36", "gene_name": "CDK6", "activity": [ { "ec_number": "2.7.11.22", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "E1BC36", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BC36" } ] }, { "ec_number": "2.7.11.22", "activity": "", "evidence": [ { "id": "E1BC36", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BC36" } ] } ] }, { "uniprot_ac": "E1BC64", "gene_name": "LIMK1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "E1BC64", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BC64" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "E1BC64", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BC64" } ] } ] }, { "uniprot_ac": "E1BC69", "gene_name": "HIPK3", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "E1BC69", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BC69" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "E1BC69", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BC69" } ] } ] }, { "uniprot_ac": "E1BCC3", "gene_name": "UHMK1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "E1BCC3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BCC3" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "E1BCC3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BCC3" } ] } ] }, { "uniprot_ac": "E1BCH5", "gene_name": "LATS1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "E1BCH5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BCH5" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "E1BCH5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BCH5" } ] } ] }, { "uniprot_ac": "E1BCU9", "gene_name": "STK11", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "E1BCU9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BCU9" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "E1BCU9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BCU9" } ] } ] }, { "uniprot_ac": "E1BDG4", "gene_name": "MAK", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "E1BDG4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BDG4" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "E1BDG4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BDG4" } ] } ] }, { "uniprot_ac": "E1BEI6", "gene_name": "ATM", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "E1BEI6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BEI6" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "E1BEI6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BEI6" } ] } ] }, { "uniprot_ac": "E1BEW4", "gene_name": "LOC613515", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "E1BEW4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BEW4" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "E1BEW4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BEW4" } ] } ] }, { "uniprot_ac": "E1BFR5", "gene_name": "MASTL", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "E1BFR5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BFR5" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "E1BFR5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BFR5" } ] } ] }, { "uniprot_ac": "E1BFV2", "gene_name": "MAP3K21", "activity": [ { "ec_number": "2.7.11.25", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "E1BFV2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BFV2" } ] }, { "ec_number": "2.7.11.25", "activity": "", "evidence": [ { "id": "E1BFV2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BFV2" } ] } ] }, { "uniprot_ac": "E1BG90", "gene_name": "DYRK2", "activity": [ { "ec_number": "2.7.12.1", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "E1BG90", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BG90" } ] }, { "ec_number": "2.7.12.1", "activity": "", "evidence": [ { "id": "E1BG90", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BG90" } ] } ] }, { "uniprot_ac": "E1BGV8", "gene_name": "MAP3K19", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "E1BGV8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BGV8" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "E1BGV8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BGV8" } ] } ] }, { "uniprot_ac": "E1BH31", "gene_name": "MAP4K1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "E1BH31", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BH31" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "E1BH31", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BH31" } ] } ] }, { "uniprot_ac": "E1BHE1", "gene_name": "TAOK3", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "E1BHE1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BHE1" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "E1BHE1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BHE1" } ] } ] }, { "uniprot_ac": "E1BI01", "gene_name": "MAP2K5", "activity": [ { "ec_number": "2.7.12.2", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "E1BI01", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BI01" } ] }, { "ec_number": "2.7.12.2", "activity": "", "evidence": [ { "id": "E1BI01", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BI01" } ] } ] }, { "uniprot_ac": "E1BI47", "gene_name": "PLK5", "activity": [ { "ec_number": "2.7.11.21", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "E1BI47", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BI47" } ] }, { "ec_number": "2.7.11.21", "activity": "", "evidence": [ { "id": "E1BI47", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BI47" } ] } ] }, { "uniprot_ac": "E1BJ19", "gene_name": "TAOK1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "E1BJ19", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BJ19" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "E1BJ19", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BJ19" } ] } ] }, { "uniprot_ac": "E1BJH5", "gene_name": "MAP4K3", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "E1BJH5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BJH5" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "E1BJH5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BJH5" } ] } ] }, { "uniprot_ac": "E1BJM5", "gene_name": "MTERF4", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "E1BJM5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BJM5" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "E1BJM5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BJM5" } ] } ] }, { "uniprot_ac": "E1BK33", "gene_name": "MAST1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "E1BK33", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BK33" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "E1BK33", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BK33" } ] } ] }, { "uniprot_ac": "E1BK52", "gene_name": "STK10", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "E1BK52", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BK52" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "E1BK52", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BK52" } ] } ] }, { "uniprot_ac": "E1BKX9", "gene_name": "CDKL5", "activity": [ { "ec_number": "2.7.11.22", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "E1BKX9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BKX9" } ] }, { "ec_number": "2.7.11.22", "activity": "", "evidence": [ { "id": "E1BKX9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BKX9" } ] } ] }, { "uniprot_ac": "E1BL08", "gene_name": "MAP3K14", "activity": [ { "ec_number": "2.7.11.25", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "E1BL08", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BL08" } ] }, { "ec_number": "2.7.11.25", "activity": "", "evidence": [ { "id": "E1BL08", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BL08" } ] } ] }, { "uniprot_ac": "E1BLQ5", "gene_name": "RPS6KB2", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "E1BLQ5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BLQ5" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "E1BLQ5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BLQ5" } ] } ] }, { "uniprot_ac": "E1BM19", "gene_name": "CDKL3", "activity": [ { "ec_number": "2.7.11.22", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "E1BM19", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BM19" } ] }, { "ec_number": "2.7.11.22", "activity": "", "evidence": [ { "id": "E1BM19", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BM19" } ] } ] }, { "uniprot_ac": "E1BMN8", "gene_name": "NLK", "activity": [ { "ec_number": "2.7.11.24", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "E1BMN8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BMN8" } ] }, { "ec_number": "2.7.11.24", "activity": "", "evidence": [ { "id": "E1BMN8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BMN8" } ] } ] }, { "uniprot_ac": "E1BN63", "gene_name": "WNK1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "E1BN63", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BN63" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "E1BN63", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BN63" } ] } ] }, { "uniprot_ac": "E1BN72", "gene_name": "NIM1K", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "E1BN72", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BN72" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "E1BN72", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BN72" } ] } ] }, { "uniprot_ac": "E1BNH0", "gene_name": "WNK2", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "E1BNH0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BNH0" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "E1BNH0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BNH0" } ] } ] }, { "uniprot_ac": "E1BNS8", "gene_name": "SIK1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "E1BNS8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BNS8" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "E1BNS8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BNS8" } ] } ] }, { "uniprot_ac": "E1BP01", "gene_name": "MYO3A", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "E1BP01", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BP01" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "E1BP01", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BP01" } ] } ] }, { "uniprot_ac": "E1BP72", "gene_name": "CDC42BPB", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "E1BP72", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BP72" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "E1BP72", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BP72" } ] } ] }, { "uniprot_ac": "E1BPB5", "gene_name": "TESK1", "activity": [ { "ec_number": "2.7.12.1", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "E1BPB5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BPB5" } ] }, { "ec_number": "2.7.12.1", "activity": "", "evidence": [ { "id": "E1BPB5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BPB5" } ] } ] }, { "uniprot_ac": "E1BPP1", "gene_name": "TTK", "activity": [ { "ec_number": "2.7.12.1", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "E1BPP1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BPP1" } ] }, { "ec_number": "2.7.12.1", "activity": "", "evidence": [ { "id": "E1BPP1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BPP1" } ] } ] }, { "uniprot_ac": "E1BPU0", "gene_name": "LRRK2", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "E1BPU0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BPU0" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "E1BPU0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BPU0" } ] } ] }, { "uniprot_ac": "E1BQ34", "gene_name": "HIPK1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "E1BQ34", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BQ34" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "E1BQ34", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BQ34" } ] } ] }, { "uniprot_ac": "F1MAZ8", "gene_name": "MARK3", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "F1MAZ8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MAZ8" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "F1MAZ8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MAZ8" } ] } ] }, { "uniprot_ac": "F1MBN7", "gene_name": "RIOK2", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "F1MBN7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MBN7" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "F1MBN7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MBN7" } ] } ] }, { "uniprot_ac": "F1MC27", "gene_name": "LMTK3", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "F1MC27", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MC27" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "F1MC27", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MC27" } ] } ] }, { "uniprot_ac": "F1MC61", "gene_name": "MAP3K11", "activity": [ { "ec_number": "2.7.11.25", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "F1MC61", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MC61" } ] }, { "ec_number": "2.7.11.25", "activity": "", "evidence": [ { "id": "F1MC61", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MC61" } ] } ] }, { "uniprot_ac": "F1MDC9", "gene_name": "PRKCE", "activity": [ { "ec_number": "2.7.11.13", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "F1MDC9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MDC9" } ] }, { "ec_number": "2.7.11.13", "activity": "", "evidence": [ { "id": "F1MDC9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MDC9" } ] } ] }, { "uniprot_ac": "F1MDS3", "gene_name": "PCK2", "activity": [ { "ec_number": "4.1.1.32", "activity": "ITP + oxaloacetate = IDP + phosphoenolpyruvate + CO2.", "evidence": [ { "id": "F1MDS3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MDS3" } ] }, { "ec_number": "4.1.1.32", "activity": "", "evidence": [ { "id": "F1MDS3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MDS3" } ] } ] }, { "uniprot_ac": "F1MF36", "gene_name": "KSR2", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "F1MF36", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MF36" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "F1MF36", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MF36" } ] } ] }, { "uniprot_ac": "F1MF50", "gene_name": "ROCK1", "activity": [ { "ec_number": "2.7.11.39", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "F1MF50", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MF50" } ] }, { "ec_number": "2.7.11.39", "activity": "", "evidence": [ { "id": "F1MF50", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MF50" } ] } ] }, { "uniprot_ac": "F1MFK1", "gene_name": "PKN2", "activity": [ { "ec_number": "2.7.11.13", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "F1MFK1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MFK1" } ] }, { "ec_number": "2.7.11.13", "activity": "", "evidence": [ { "id": "F1MFK1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MFK1" } ] } ] }, { "uniprot_ac": "F1MG29", "gene_name": "TSSK3", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "F1MG29", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MG29" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "F1MG29", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MG29" } ] } ] }, { "uniprot_ac": "F1MG35", "gene_name": "CIITA", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "F1MG35", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MG35" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "F1MG35", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MG35" } ] } ] }, { "uniprot_ac": "F1MG77", "gene_name": "HASPIN", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "F1MG77", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MG77" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "F1MG77", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MG77" } ] } ] }, { "uniprot_ac": "F1MGX2", "gene_name": "MAP3K13", "activity": [ { "ec_number": "2.7.11.25", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "F1MGX2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MGX2" } ] }, { "ec_number": "2.7.11.25", "activity": "", "evidence": [ { "id": "F1MGX2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MGX2" } ] } ] }, { "uniprot_ac": "F1MH23", "gene_name": "MAPKAPK5", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "F1MH23", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MH23" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "F1MH23", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MH23" } ] } ] }, { "uniprot_ac": "F1MH24", "gene_name": "AAK1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "F1MH24", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MH24" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "F1MH24", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MH24" } ] } ] }, { "uniprot_ac": "F1MH45", "gene_name": "CDC42BPA", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "F1MH45", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MH45" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "F1MH45", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MH45" } ] } ] }, { "uniprot_ac": "F1MI60", "gene_name": "MAP4K4", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "F1MI60", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MI60" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "F1MI60", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MI60" } ] } ] }, { "uniprot_ac": "F1MIB2", "gene_name": "GAK", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "F1MIB2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MIB2" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "F1MIB2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MIB2" } ] } ] }, { "uniprot_ac": "F1MJ55", "gene_name": "CSNK2A2", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "F1MJ55", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MJ55" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "F1MJ55", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MJ55" } ] } ] }, { "uniprot_ac": "F1MKK7", "gene_name": "PKMYT1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "F1MKK7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MKK7" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "F1MKK7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MKK7" } ] } ] }, { "uniprot_ac": "F1MKW8", "gene_name": "SIK2", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "F1MKW8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MKW8" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "F1MKW8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MKW8" } ] } ] }, { "uniprot_ac": "F1MKY9", "gene_name": "ALPK2", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "F1MKY9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MKY9" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "F1MKY9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MKY9" } ] } ] }, { "uniprot_ac": "F1MLY7", "gene_name": "ATR", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "F1MLY7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MLY7" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "F1MLY7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MLY7" } ] } ] }, { "uniprot_ac": "F1MM88", "gene_name": "NEK9", "activity": [ { "ec_number": "2.7.11.38", "activity": "L-threonyl-[protein] + ATP = O-phospho-L-threonyl-[protein] + ADP + H(+).", "evidence": [ { "id": "F1MM88", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MM88" } ] }, { "ec_number": "2.7.11.38", "activity": "", "evidence": [ { "id": "F1MM88", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MM88" } ] } ] }, { "uniprot_ac": "F1MN35", "gene_name": "PDIK1L", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "F1MN35", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MN35" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "F1MN35", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MN35" } ] } ] }, { "uniprot_ac": "F1MNP4", "gene_name": "RPS6KB1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "F1MNP4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MNP4" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "F1MNP4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MNP4" } ] } ] }, { "uniprot_ac": "F1MPF0", "gene_name": "TRPM7", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "F1MPF0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MPF0" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "F1MPF0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MPF0" } ] } ] }, { "uniprot_ac": "F1MPI8", "gene_name": "CDK8", "activity": [ { "ec_number": "2.7.11.22", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "F1MPI8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MPI8" } ] }, { "ec_number": "2.7.11.23", "activity": "[DNA-directed RNA polymerase] + ATP = phospho-[DNA-directed RNA polymerase] + ADP + H(+).", "evidence": [ { "id": "F1MPI8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MPI8" } ] }, { "ec_number": "2.7.11.22", "activity": "", "evidence": [ { "id": "F1MPI8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MPI8" } ] }, { "ec_number": "2.7.11.23", "activity": "", "evidence": [ { "id": "F1MPI8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MPI8" } ] } ] }, { "uniprot_ac": "F1MQ96", "gene_name": "PRKCI", "activity": [ { "ec_number": "2.7.11.13", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "F1MQ96", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MQ96" } ] }, { "ec_number": "2.7.11.13", "activity": "", "evidence": [ { "id": "F1MQ96", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MQ96" } ] } ] }, { "uniprot_ac": "F1MSI1", "gene_name": "STK17B", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "F1MSI1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MSI1" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "F1MSI1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MSI1" } ] } ] }, { "uniprot_ac": "F1MSV4", "gene_name": "SGK3", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "F1MSV4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MSV4" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "F1MSV4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MSV4" } ] } ] }, { "uniprot_ac": "F1MSX4", "gene_name": "MAP3K2", "activity": [ { "ec_number": "2.7.11.25", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "F1MSX4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MSX4" } ] }, { "ec_number": "2.7.11.25", "activity": "", "evidence": [ { "id": "F1MSX4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MSX4" } ] } ] }, { "uniprot_ac": "F1MU35", "gene_name": "PRKCG", "activity": [ { "ec_number": "2.7.11.13", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "F1MU35", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MU35" } ] }, { "ec_number": "2.7.11.13", "activity": "", "evidence": [ { "id": "F1MU35", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MU35" } ] } ] }, { "uniprot_ac": "F1MUU2", "gene_name": "STK35", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "F1MUU2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MUU2" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "F1MUU2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MUU2" } ] } ] }, { "uniprot_ac": "F1MVR0", "gene_name": "CDK19", "activity": [ { "ec_number": "2.7.11.22", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "F1MVR0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MVR0" } ] }, { "ec_number": "2.7.11.22", "activity": "", "evidence": [ { "id": "F1MVR0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MVR0" } ] } ] }, { "uniprot_ac": "F1MVV5", "gene_name": "MAPK4", "activity": [ { "ec_number": "2.7.11.24", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "F1MVV5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MVV5" } ] }, { "ec_number": "2.7.11.24", "activity": "", "evidence": [ { "id": "F1MVV5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MVV5" } ] } ] }, { "uniprot_ac": "F1MWN0", "gene_name": "EIF2AK1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "F1MWN0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MWN0" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "F1MWN0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MWN0" } ] } ] }, { "uniprot_ac": "F1MWP1", "gene_name": "BUB1B", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "F1MWP1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MWP1" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "F1MWP1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MWP1" } ] } ] }, { "uniprot_ac": "F1MXH6", "gene_name": "MAP3K5", "activity": [ { "ec_number": "2.7.11.25", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "F1MXH6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MXH6" } ] }, { "ec_number": "2.7.11.25", "activity": "", "evidence": [ { "id": "F1MXH6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MXH6" } ] } ] }, { "uniprot_ac": "F1MY55", "gene_name": "PAK5", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "F1MY55", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MY55" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "F1MY55", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MY55" } ] } ] }, { "uniprot_ac": "F1MY82", "gene_name": "PRKCH", "activity": [ { "ec_number": "2.7.11.13", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "F1MY82", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MY82" } ] }, { "ec_number": "2.7.11.13", "activity": "", "evidence": [ { "id": "F1MY82", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MY82" } ] } ] }, { "uniprot_ac": "F1MY86", "gene_name": "AURKC", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "F1MY86", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MY86" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "F1MY86", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MY86" } ] } ] }, { "uniprot_ac": "F1MYG2", "gene_name": "TLK1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "F1MYG2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MYG2" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "F1MYG2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MYG2" } ] } ] }, { "uniprot_ac": "F1MYM3", "gene_name": "PIK3CB", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "F1MYM3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MYM3" } ] }, { "ec_number": "2.7.1.153", "activity": "a 1,2-diacyl-sn-glycero-3-phospho-(1D-myo-inositol-4,5-bisphosphate) + ATP = a 1,2-diacyl-sn-glycero-3-phospho-(1D-myo-inositol-3,4,5-trisphosphate) + ADP + H(+).", "evidence": [ { "id": "F1MYM3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MYM3" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "F1MYM3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MYM3" } ] }, { "ec_number": "2.7.1.153", "activity": "", "evidence": [ { "id": "F1MYM3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MYM3" } ] } ] }, { "uniprot_ac": "F1MYV9", "gene_name": "OXSR1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "F1MYV9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MYV9" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "F1MYV9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MYV9" } ] } ] }, { "uniprot_ac": "F1N063", "gene_name": "CAMK1D", "activity": [ { "ec_number": "2.7.11.17", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "F1N063", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1N063" } ] }, { "ec_number": "2.7.11.17", "activity": "", "evidence": [ { "id": "F1N063", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1N063" } ] } ] }, { "uniprot_ac": "F1N2S7", "gene_name": "TSSK6", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "F1N2S7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1N2S7" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "F1N2S7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1N2S7" } ] } ] }, { "uniprot_ac": "F1N332", "gene_name": "ULK3", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "F1N332", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1N332" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "F1N332", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1N332" } ] } ] }, { "uniprot_ac": "F1N3W6", "gene_name": "MAP3K15", "activity": [ { "ec_number": "2.7.11.25", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "F1N3W6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1N3W6" } ] }, { "ec_number": "2.7.11.25", "activity": "", "evidence": [ { "id": "F1N3W6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1N3W6" } ] } ] }, { "uniprot_ac": "F1N5K1", "gene_name": "CDK11B", "activity": [ { "ec_number": "2.7.11.22", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "F1N5K1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1N5K1" } ] }, { "ec_number": "2.7.11.23", "activity": "[DNA-directed RNA polymerase] + ATP = phospho-[DNA-directed RNA polymerase] + ADP + H(+).", "evidence": [ { "id": "F1N5K1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1N5K1" } ] }, { "ec_number": "2.7.11.23", "activity": "", "evidence": [ { "id": "F1N5K1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1N5K1" } ] }, { "ec_number": "2.7.11.22", "activity": "", "evidence": [ { "id": "F1N5K1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1N5K1" } ] } ] }, { "uniprot_ac": "F1N5U0", "gene_name": "ALPK3", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "F1N5U0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1N5U0" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "F1N5U0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1N5U0" } ] } ] }, { "uniprot_ac": "F1N664", "gene_name": "MAP2K7", "activity": [ { "ec_number": "2.7.12.2", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "F1N664", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1N664" } ] }, { "ec_number": "2.7.12.2", "activity": "", "evidence": [ { "id": "F1N664", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1N664" } ] } ] }, { "uniprot_ac": "F1N6C1", "gene_name": "LRRK1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "F1N6C1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1N6C1" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "F1N6C1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1N6C1" } ] } ] }, { "uniprot_ac": "F6PN06", "gene_name": "TNK2", "activity": [ { "ec_number": "2.7.10.2", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "F6PN06", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F6PN06" } ] }, { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "F6PN06", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F6PN06" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "F6PN06", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F6PN06" } ] }, { "ec_number": "2.7.10.2", "activity": "", "evidence": [ { "id": "F6PN06", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F6PN06" } ] } ] }, { "uniprot_ac": "F6Q5B6", "gene_name": "EIF2AK2", "activity": [ { "ec_number": "2.7.10.2", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "F6Q5B6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F6Q5B6" } ] }, { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "F6Q5B6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F6Q5B6" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "F6Q5B6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F6Q5B6" } ] }, { "ec_number": "2.7.10.2", "activity": "", "evidence": [ { "id": "F6Q5B6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F6Q5B6" } ] } ] }, { "uniprot_ac": "F6Q5Z6", "gene_name": "BUB1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "F6Q5Z6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F6Q5Z6" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "F6Q5Z6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F6Q5Z6" } ] } ] }, { "uniprot_ac": "F6Q6K1", "gene_name": "CHEK1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "F6Q6K1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F6Q6K1" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "F6Q6K1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F6Q6K1" } ] } ] }, { "uniprot_ac": "F6Q9U9", "gene_name": "PNCK", "activity": [ { "ec_number": "2.7.11.17", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "F6Q9U9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F6Q9U9" } ] }, { "ec_number": "2.7.11.17", "activity": "", "evidence": [ { "id": "F6Q9U9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F6Q9U9" } ] } ] }, { "uniprot_ac": "F6QTX4", "gene_name": "RIPK3", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "F6QTX4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F6QTX4" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "F6QTX4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F6QTX4" } ] } ] }, { "uniprot_ac": "F6QVY2", "gene_name": "CDK20", "activity": [ { "ec_number": "2.7.11.22", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "F6QVY2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F6QVY2" } ] }, { "ec_number": "2.7.11.22", "activity": "", "evidence": [ { "id": "F6QVY2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F6QVY2" } ] } ] }, { "uniprot_ac": "F6QY93", "gene_name": "CDK3", "activity": [ { "ec_number": "2.7.11.22", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "F6QY93", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F6QY93" } ] }, { "ec_number": "2.7.11.22", "activity": "", "evidence": [ { "id": "F6QY93", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F6QY93" } ] } ] }, { "uniprot_ac": "F6RD87", "gene_name": "SRPK3", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "F6RD87", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F6RD87" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "F6RD87", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F6RD87" } ] } ] }, { "uniprot_ac": "F6RG88", "gene_name": "NEK4", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "F6RG88", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F6RG88" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "F6RG88", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F6RG88" } ] } ] }, { "uniprot_ac": "F6RLA2", "gene_name": "TSSK4", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "F6RLA2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F6RLA2" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "F6RLA2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F6RLA2" } ] } ] }, { "uniprot_ac": "F6RP02", "gene_name": "PIM2", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "F6RP02", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F6RP02" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "F6RP02", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F6RP02" } ] } ] }, { "uniprot_ac": "F6RPH3", "gene_name": "MAPK13", "activity": [ { "ec_number": "2.7.11.24", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "F6RPH3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F6RPH3" } ] }, { "ec_number": "2.7.11.24", "activity": "", "evidence": [ { "id": "F6RPH3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F6RPH3" } ] } ] }, { "uniprot_ac": "G3MX00", "gene_name": "", "activity": [ { "ec_number": "2.7.11.22", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "G3MX00", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3MX00" } ] }, { "ec_number": "2.7.11.22", "activity": "", "evidence": [ { "id": "G3MX00", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3MX00" } ] } ] }, { "uniprot_ac": "G3N022", "gene_name": "SPEG", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "G3N022", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3N022" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "G3N022", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3N022" } ] } ] }, { "uniprot_ac": "G3N2D2", "gene_name": "TSSK1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "G3N2D2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3N2D2" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "G3N2D2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3N2D2" } ] } ] }, { "uniprot_ac": "G3N2F6", "gene_name": "PIM3", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "G3N2F6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3N2F6" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "G3N2F6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3N2F6" } ] } ] }, { "uniprot_ac": "G3N2J4", "gene_name": "TTBK1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "G3N2J4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3N2J4" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "G3N2J4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3N2J4" } ] } ] }, { "uniprot_ac": "G5E518", "gene_name": "CDK12", "activity": [ { "ec_number": "2.7.11.22", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "G5E518", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G5E518" } ] }, { "ec_number": "2.7.11.23", "activity": "[DNA-directed RNA polymerase] + ATP = phospho-[DNA-directed RNA polymerase] + ADP + H(+).", "evidence": [ { "id": "G5E518", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G5E518" } ] }, { "ec_number": "2.7.11.22", "activity": "", "evidence": [ { "id": "G5E518", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G5E518" } ] }, { "ec_number": "2.7.11.23", "activity": "", "evidence": [ { "id": "G5E518", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G5E518" } ] } ] }, { "uniprot_ac": "G5E577", "gene_name": "MAPK6", "activity": [ { "ec_number": "2.7.11.24", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "G5E577", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G5E577" } ] }, { "ec_number": "2.7.11.24", "activity": "", "evidence": [ { "id": "G5E577", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G5E577" } ] } ] }, { "uniprot_ac": "G5E5A0", "gene_name": "STK17A", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "G5E5A0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G5E5A0" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "G5E5A0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G5E5A0" } ] } ] }, { "uniprot_ac": "G5E5D4", "gene_name": "MARK1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "G5E5D4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G5E5D4" } ] }, { "ec_number": "2.7.11.26", "activity": "L-seryl-[tau protein] + ATP = O-phospho-L-seryl-[tau protein] + ADP + H(+).", "evidence": [ { "id": "G5E5D4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G5E5D4" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "G5E5D4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G5E5D4" } ] }, { "ec_number": "2.7.11.26", "activity": "", "evidence": [ { "id": "G5E5D4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G5E5D4" } ] } ] }, { "uniprot_ac": "G5E5K2", "gene_name": "MASTL", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "G5E5K2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G5E5K2" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "G5E5K2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G5E5K2" } ] } ] }, { "uniprot_ac": "H2XJE8", "gene_name": "AAK1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "H2XJE8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/H2XJE8" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "H2XJE8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/H2XJE8" } ] } ] }, { "uniprot_ac": "H2XJE9", "gene_name": "NLK", "activity": [ { "ec_number": "2.7.11.24", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "H2XJE9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/H2XJE9" } ] }, { "ec_number": "2.7.11.24", "activity": "", "evidence": [ { "id": "H2XJE9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/H2XJE9" } ] } ] }, { "uniprot_ac": "P00516", "gene_name": "PRKG1", "activity": [ { "ec_number": "2.7.11.12", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "P00516", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P00516" } ] }, { "ec_number": "2.7.11.12", "activity": "", "evidence": [ { "id": "P00516", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P00516" } ] } ] }, { "uniprot_ac": "P00517", "gene_name": "PRKACA", "activity": [ { "ec_number": "2.7.11.11", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "P00517", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P00517" } ] }, { "ec_number": "2.7.11.11", "activity": "", "evidence": [ { "id": "P00517", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P00517" } ] } ] }, { "uniprot_ac": "P04409", "gene_name": "PRKCA", "activity": [ { "ec_number": "2.7.11.13", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "P04409", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P04409" } ] }, { "ec_number": "2.7.11.13", "activity": "", "evidence": [ { "id": "P04409", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P04409" } ] } ] }, { "uniprot_ac": "P05126", "gene_name": "PRKCB", "activity": [ { "ec_number": "2.7.11.13", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "P05126", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P05126" } ] }, { "ec_number": "2.7.11.13", "activity": "", "evidence": [ { "id": "P05126", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P05126" } ] } ] }, { "uniprot_ac": "P05128", "gene_name": "PRKCG", "activity": [ { "ec_number": "2.7.11.13", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "P05128", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P05128" } ] }, { "ec_number": "2.7.11.13", "activity": "", "evidence": [ { "id": "P05128", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P05128" } ] } ] }, { "uniprot_ac": "P05131", "gene_name": "PRKACB", "activity": [ { "ec_number": "2.7.11.11", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "P05131", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P05131" } ] }, { "ec_number": "2.7.11.11", "activity": "", "evidence": [ { "id": "P05131", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P05131" } ] } ] }, { "uniprot_ac": "P20427", "gene_name": "CSNK2A2", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "P20427", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P20427" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "P20427", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P20427" } ] } ] }, { "uniprot_ac": "P32871", "gene_name": "PIK3CA", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "P32871", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P32871" } ] }, { "ec_number": "2.7.1.153", "activity": "a 1,2-diacyl-sn-glycero-3-phospho-(1D-myo-inositol-4,5-bisphosphate) + ATP = a 1,2-diacyl-sn-glycero-3-phospho-(1D-myo-inositol-3,4,5-trisphosphate) + ADP + H(+).", "evidence": [ { "id": "P32871", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P32871" } ] }, { "ec_number": "2.7.1.137", "activity": "a 1,2-diacyl-sn-glycero-3-phospho-(1D-myo-inositol) + ATP = a 1,2-diacyl-sn-glycero-3-phospho-(1D-myo-inositol-3-phosphate) + ADP + H(+).", "evidence": [ { "id": "P32871", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P32871" } ] }, { "ec_number": "2.7.1.153", "activity": "", "evidence": [ { "id": "P32871", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P32871" } ] }, { "ec_number": "2.7.1.137", "activity": "", "evidence": [ { "id": "P32871", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P32871" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "P32871", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P32871" } ] } ] }, { "uniprot_ac": "P35507", "gene_name": "CSNK1B", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "P35507", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P35507" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "P35507", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P35507" } ] } ] }, { "uniprot_ac": "P35508", "gene_name": "CSNK1D", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "P35508", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P35508" } ] }, { "ec_number": "2.7.11.26", "activity": "L-seryl-[tau protein] + ATP = O-phospho-L-seryl-[tau protein] + ADP + H(+).", "evidence": [ { "id": "P35508", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P35508" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "P35508", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P35508" } ] } ] }, { "uniprot_ac": "P35509", "gene_name": "CSNK1G3", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "P35509", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P35509" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "P35509", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P35509" } ] } ] }, { "uniprot_ac": "P46196", "gene_name": "MAPK1", "activity": [ { "ec_number": "2.7.11.24", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "P46196", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P46196" } ] }, { "ec_number": "2.7.11.24", "activity": "", "evidence": [ { "id": "P46196", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P46196" } ] } ] }, { "uniprot_ac": "P48734", "gene_name": "CDK1", "activity": [ { "ec_number": "2.7.11.22", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "P48734", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P48734" } ] }, { "ec_number": "2.7.11.23", "activity": "[DNA-directed RNA polymerase] + ATP = phospho-[DNA-directed RNA polymerase] + ADP + H(+).", "evidence": [ { "id": "P48734", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P48734" } ] }, { "ec_number": "2.7.11.23", "activity": "", "evidence": [ { "id": "P48734", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P48734" } ] }, { "ec_number": "2.7.11.22", "activity": "", "evidence": [ { "id": "P48734", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P48734" } ] } ] }, { "uniprot_ac": "P52175", "gene_name": "NME1", "activity": [ { "ec_number": "3.1.11.-", "activity": "", "evidence": [ { "id": "P52175", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P52175" } ] }, { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "P52175", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P52175" } ] }, { "ec_number": "2.7.4.6", "activity": "UDP + ATP = UTP + ADP.", "evidence": [ { "id": "P52175", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P52175" } ] }, { "ec_number": "2.7.13.3", "activity": "ATP + protein L-histidine = ADP + protein N-phospho-L-histidine.", "evidence": [ { "id": "P52175", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P52175" } ] }, { "ec_number": "2.7.4.18", "activity": "(2E,6E)-farnesyl diphosphate + ATP = (2E,6E)-farnesyl triphosphate + ADP.", "evidence": [ { "id": "P52175", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P52175" } ] }, { "ec_number": "3.1.24.-", "activity": "", "evidence": [ { "id": "P52175", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P52175" } ] }, { "ec_number": "2.7.4.6", "activity": "", "evidence": [ { "id": "P52175", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P52175" } ] } ] }, { "uniprot_ac": "P67827", "gene_name": "CSNK1A1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "P67827", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P67827" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "P67827", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P67827" } ] } ] }, { "uniprot_ac": "P68399", "gene_name": "CSNK2A1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "P68399", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P68399" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "P68399", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P68399" } ] } ] }, { "uniprot_ac": "Q01314", "gene_name": "AKT1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "Q01314", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q01314" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "Q01314", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q01314" } ] } ] }, { "uniprot_ac": "Q02399", "gene_name": "CDK5", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "Q02399", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q02399" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "Q02399", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q02399" } ] } ] }, { "uniprot_ac": "Q08DZ2", "gene_name": "PRP4K", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "Q08DZ2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q08DZ2" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "Q08DZ2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q08DZ2" } ] } ] }, { "uniprot_ac": "Q08E52", "gene_name": "PAK1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "Q08E52", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q08E52" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "Q08E52", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q08E52" } ] } ] }, { "uniprot_ac": "Q0V7M1", "gene_name": "PSKH1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "Q0V7M1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q0V7M1" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "Q0V7M1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q0V7M1" } ] } ] }, { "uniprot_ac": "Q0VD22", "gene_name": "STK33", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "Q0VD22", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q0VD22" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "Q0VD22", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q0VD22" } ] } ] }, { "uniprot_ac": "Q17QV9", "gene_name": "STK40", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "Q17QV9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q17QV9" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "Q17QV9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q17QV9" } ] } ] }, { "uniprot_ac": "Q17R13", "gene_name": "TNK2", "activity": [ { "ec_number": "2.7.10.2", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "Q17R13", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q17R13" } ] }, { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "Q17R13", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q17R13" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "Q17R13", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q17R13" } ] }, { "ec_number": "2.7.10.2", "activity": "", "evidence": [ { "id": "Q17R13", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q17R13" } ] } ] }, { "uniprot_ac": "Q1RMT7", "gene_name": "RIOK3", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "Q1RMT7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q1RMT7" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "Q1RMT7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q1RMT7" } ] } ] }, { "uniprot_ac": "Q1RMT8", "gene_name": "IRAK4", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "Q1RMT8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q1RMT8" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "Q1RMT8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q1RMT8" } ] } ] }, { "uniprot_ac": "Q28021", "gene_name": "ROCK2", "activity": [ { "ec_number": "2.7.11.39", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "Q28021", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q28021" } ] }, { "ec_number": "2.7.11.39", "activity": "", "evidence": [ { "id": "Q28021", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q28021" } ] } ] }, { "uniprot_ac": "Q2HJF7", "gene_name": "CAMK2D", "activity": [ { "ec_number": "2.7.11.17", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "Q2HJF7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q2HJF7" } ] }, { "ec_number": "2.7.11.17", "activity": "", "evidence": [ { "id": "Q2HJF7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q2HJF7" } ] } ] }, { "uniprot_ac": "Q2KIP2", "gene_name": "HASPIN", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "Q2KIP2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q2KIP2" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "Q2KIP2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q2KIP2" } ] } ] }, { "uniprot_ac": "Q2KJG8", "gene_name": "BCKDK", "activity": [ { "ec_number": "2.7.11.-", "activity": "", "evidence": [ { "id": "Q2KJG8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q2KJG8" } ] }, { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "Q2KJG8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q2KJG8" } ] }, { "ec_number": "2.7.11.4", "activity": "L-seryl-[3-methyl-2-oxobutanoate dehydrogenase] + ATP = O-phospho-L-seryl-[3-methyl-2-oxobutanoate dehydrogenase] + ADP + H(+).", "evidence": [ { "id": "Q2KJG8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q2KJG8" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "Q2KJG8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q2KJG8" } ] } ] }, { "uniprot_ac": "Q2LGB3", "gene_name": "IRAK1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "Q2LGB3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q2LGB3" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "Q2LGB3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q2LGB3" } ] } ] }, { "uniprot_ac": "Q2TA06", "gene_name": "AURKA", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "Q2TA06", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q2TA06" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "Q2TA06", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q2TA06" } ] } ] }, { "uniprot_ac": "Q2TA25", "gene_name": "PLK1", "activity": [ { "ec_number": "2.7.11.21", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "Q2TA25", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q2TA25" } ] }, { "ec_number": "2.7.11.21", "activity": "", "evidence": [ { "id": "Q2TA25", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q2TA25" } ] } ] }, { "uniprot_ac": "Q2TBL8", "gene_name": "CDK10", "activity": [ { "ec_number": "2.7.11.22", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "Q2TBL8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q2TBL8" } ] }, { "ec_number": "2.7.11.22", "activity": "", "evidence": [ { "id": "Q2TBL8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q2TBL8" } ] } ] }, { "uniprot_ac": "Q2YDN8", "gene_name": "VRK3", "activity": [ { "ec_number": "2.7.11.22", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "Q2YDN8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q2YDN8" } ] }, { "ec_number": "2.7.11.22", "activity": "", "evidence": [ { "id": "Q2YDN8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q2YDN8" } ] } ] }, { "uniprot_ac": "Q32KY4", "gene_name": "CDK4", "activity": [ { "ec_number": "2.7.11.22", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "Q32KY4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q32KY4" } ] }, { "ec_number": "2.7.11.22", "activity": "", "evidence": [ { "id": "Q32KY4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q32KY4" } ] } ] }, { "uniprot_ac": "Q32L23", "gene_name": "LIMK2", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "Q32L23", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q32L23" } ] }, { "ec_number": 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"categories": [ "Protein" ] }, { "id": "A0AAA9T2F9-1", "url": "https://www.uniprot.org/uniprotkb/A0AAA9T2F9-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0AAA9T816", "url": "https://www.uniprot.org/uniprotkb/A0AAA9T816", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0AAA9T816-1", "url": "https://www.uniprot.org/uniprotkb/A0AAA9T816-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0AAA9TF13", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TF13", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0AAA9TF13-1", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TF13-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "F6R672", "url": "https://www.uniprot.org/uniprotkb/F6R672", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "F6R672-1", "url": "https://www.uniprot.org/uniprotkb/F6R672-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MAGAEGGPGDGELWQTWLPNHAVFLRLREGLKNQSSTETEKPASSLPSSPPLPPQLLTRNLVLGLGGELFLWDPEESSFLVVRLRGPSGAGEEPSLSQYQRLLCINPPLFEIYQVLLSPTQHHVALIGIKGLMILELPKRWGKNSEFEGGKSTVNCSTTPVAERFFTSSTSLTLKHAAWYPSEMLEPHIVLLTSDNVIRIYSLREPQTPTKVIVLSEAEEESLILNKGRAYTASLGETAVAFDFGPLSAVPKHIFGQKGKEEVAAYPLYILYENGETFLTYISLLHSPGSVGKLLGPLPMHPAAEDNYGYDACAVLCLPCVPNILVIATESGMLYHCVVLEGEEEDDQTSEKSWDSRADLIPSLYVFECVELELALKLASGEDEPFDSDFSCPIKLHRDPKCPSRYHCTHEAGVHSVGLTWIHKLHKFLGSDEEDKDSLQELATEQKCFVEHILCTKPLPCRQPAPIRGFWIVPDILGPTMICITSTYECLIRPLLSTVHPASPPLLCTREDVEVAESPLRILAETPDSFEKHIRSILQRSVANPAFLNCFIQLRIEFFLRSSEKDMAPPPEECLQLISRATQVFREQYILKQDLAKEEIQRRVKLLCDQKKKQLEDLNYCREERKSLREMAERLADKYEEAKEKQEDIMNRMKKVLHSFHSQLPVLSDSERDMKKELQLIPDQLRHLGNAIKQVTMKKDYQQRKMEKVLSPQKPTITLSAYQRKCIQSILKEEGEHIREMVKQINDIRNHVNF", "length": 754, "header": "tr|F6R672-1|F6R672_BOVIN Isoform 1 of Nucleoporin 88 OS=Bos taurus OX=9913 GN=NUP88 PE=4 SV=1 CANONICAL=F6R672-1" }, "isoforms": [ { "isoform_ac": "A0AAA9T2F9-1", "url": "https://www.uniprot.org/uniprotkb/A0AAA9T2F9/entry", "sequence": { "sequence": "MAGAEGGPGDGELWQTWLPNHAVFLRLREGLKNQSSTETEKPASSLPSSPPLPPQLLTRNLVLGLGGELFLWDPEESSFLVVRLRGPSGAGEEPSLSQYQRLLCINPPLFEIYQVLLSPTQHHVALIGIKGLMILELPKRWGKNSEFEGGKSTVNCSTTPVAERFFTSSTSLTLKHAAWYPSEMLEPHIVLLTSDNVIRRAYTASLGETAVAFDFGPLSAVPKHIFGQKGKEEVAAYPLYILYENGETFLTYISLLHSPGSVGKLLGPLPMHPAAEDNYGYDACAVLCLPCVPNILVIATESGMLYHCVVLEGEEEDDQTSEKSWDSRADLIPSLYVFECVELELALKLASGEDEPFDSDFSCPIKLHRDPKCPSRYHCTHEAGVHSVGLTWIHKLHKFLGSDEEDKDSLQELATEQKCFVEHILCTKPLPCRQPAPIRGFWIVPDILGPTMICITSTYECLIRPLLSTVHPASPPLLCTREDVEVAESPLRILAETPDSFEKHIRSILQRSVANPAFLKSSEKDMAPPPEECLQLISRATQVFREQYILKQDLAKEEIQRRVKLLCDQKKKQLEDLNYCREERKSLREMAERLADKYEEAKEKQEDIMNRMKKVLHSFHSQLPVLSDSERDMKKELQLIPDQLRHLGNAIKQVTMKKDYQQRKMEKVLSPQKPTITLSAYQRKCIQSILKEEGEHIREMVKQINDIRNHVNF", "length": 713, "header": "tr|A0AAA9T2F9-1|F6R672_BOVIN Computationally mapped isoform of Nucleoporin 88 OS=Bos taurus OX=9913 GN=NUP88 PE=4 SV=1 CANONICAL=F6R672-1" }, "locus": { "chromosome": "19", "start_pos": 26149453, "end_pos": 26128027, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000128689.2", "url": "https://www.ensembl.org/id/ENSBTAT00000128689.2" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000089847.1", "url": "https://www.ensembl.org/id/ENSBTAP00000089847.1" } ] } }, { "isoform_ac": "A0AAA9T816-1", "url": "https://www.uniprot.org/uniprotkb/A0AAA9T816/entry", "sequence": { "sequence": "MAGAEGGPGDGELWQTWLPNHAVFLRLREGLKNQSSTETEKPASSLPSSPPLPPQLLTRNLVLGLGGELFLWDPEESSFLVVRLRGPSGAGEEPSLSQYQRLLCINPPLFEIYQVLLSPTQHHVALIGIKGLMILELPKRWGKNSEFEGGKSTVNCSTTPVAERFFTSSTSLTLKHAAWYPSEMLEPHIVLLTSDNVIRIYSLREPQTPTKVIVLSEAEEESLILNKGRAYTASLGETAVAFDFGPLSAVPKHIFGQKGKEEVAAYPLYILYENGETFLTYISLLHSPGSVGKLLGPLPMHPAAEDNYGYDACAVLCLPCVPNILVIATESGMLYHCVVLEGEEEDDQTSEKSWDSRADLIPSLYVFECVELELALKLASGEDEPFDSDFSCPIKLHRDPKCPSRYHCTHEAGVHSVGLTWIHKLHKFLGSDEEDKDSLQELATEQKCFVEHILCTKPLPCRQPAPIRGFWIVPDILGPTMICITSTYECLIRPLLCFIQLRIEFFLRSSEKDMAPPPEECLQLISRATQVFREQYILKQDLAKEEIQRRVKLLCDQKKKQLEDLNYCREERKSLREMAERLADKYEEAKEKQEDIMNRMKKVLHSFHSQLPVLSDSERDMKKELQLIPDQLRHLGNAIKQVTMKKDYQQRKMEKVLSPQKPTITLSAYQRKCIQSILKEEGEHIREMVKQINDIRNHVNF", "length": 701, "header": "tr|A0AAA9T816-1|F6R672_BOVIN Computationally mapped isoform of Nucleoporin 88 OS=Bos taurus OX=9913 GN=NUP88 PE=4 SV=1 CANONICAL=F6R672-1" }, "locus": { "chromosome": "19", "start_pos": 26149453, "end_pos": 26128027, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000133616.2", "url": "https://www.ensembl.org/id/ENSBTAT00000133616.2" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000091991.1", "url": "https://www.ensembl.org/id/ENSBTAP00000091991.1" } ] } }, { "isoform_ac": "A0AAA9TF13-1", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TF13/entry", "sequence": { "sequence": "MAGAEGGPGDGELWQTWLPNHAVFLRLREGLKNQSSTETEKPASSLPSSPPLPPQLLTRNLVLGLGGELFLWDPEESSFLVVRLRGPSGAGEEPSLSQYQRLLCINPPLFEIYQVLLSPTQHHVALIGIKGLMILELPKRWGKNSEFEGGKSTVNCSTTPVAERFFTSSTSLTLKHAAWYPSEMLEPHIVLLTSDNVIRIYSLREPQTPTKVIVLSEAEEESLILNKGRAYTASLGETAVAFDFGPLSAVPKHIFGQKGKEEVAAYPLYILYENGETFLTYISLLHSPGSVGKLLGPLPMHPAAEDNYGYDACAVLCLPCVPNILVIATESGMLYHCVVLEGEEEDDQTSEKSWDSRADLIPSLYVFECVELELALKLASGEDEPFDSDFSCPIKLHRDPKCPSRYHCTHEAGVHSVGLTWIHKLHKFLGSDEEDKDSLQELATEQKCFVEHILCTKPLPCRQPAPIRGFWIVPDILGPTMICITSTYECLIRPLLVKLLCDQKKKQLEDLNYCREERKSLREMAERLADKYEEAKEKQEDIMNRMKKVLHSFHSQLPVLSDSERDMKKELQLIPDQLRHLGNAIKQVTMKKDYQQRKMEKVLSPQKPTITLSAYQRKCIQSILKEEGEHIREMVKQINDIRNHVNF", "length": 647, "header": "tr|A0AAA9TF13-1|F6R672_BOVIN Computationally mapped isoform of Nucleoporin 88 OS=Bos taurus OX=9913 GN=NUP88 PE=4 SV=1 CANONICAL=F6R672-1" }, "locus": { "chromosome": "19", "start_pos": 26149453, "end_pos": 26128027, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000132452.2", "url": "https://www.ensembl.org/id/ENSBTAT00000132452.2" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000095433.1", "url": "https://www.ensembl.org/id/ENSBTAP00000095433.1" } ] } }, { "isoform_ac": "F6R672-1", "url": "https://www.uniprot.org/uniprotkb/F6R672/entry", "sequence": { "sequence": "MAGAEGGPGDGELWQTWLPNHAVFLRLREGLKNQSSTETEKPASSLPSSPPLPPQLLTRNLVLGLGGELFLWDPEESSFLVVRLRGPSGAGEEPSLSQYQRLLCINPPLFEIYQVLLSPTQHHVALIGIKGLMILELPKRWGKNSEFEGGKSTVNCSTTPVAERFFTSSTSLTLKHAAWYPSEMLEPHIVLLTSDNVIRIYSLREPQTPTKVIVLSEAEEESLILNKGRAYTASLGETAVAFDFGPLSAVPKHIFGQKGKEEVAAYPLYILYENGETFLTYISLLHSPGSVGKLLGPLPMHPAAEDNYGYDACAVLCLPCVPNILVIATESGMLYHCVVLEGEEEDDQTSEKSWDSRADLIPSLYVFECVELELALKLASGEDEPFDSDFSCPIKLHRDPKCPSRYHCTHEAGVHSVGLTWIHKLHKFLGSDEEDKDSLQELATEQKCFVEHILCTKPLPCRQPAPIRGFWIVPDILGPTMICITSTYECLIRPLLSTVHPASPPLLCTREDVEVAESPLRILAETPDSFEKHIRSILQRSVANPAFLNCFIQLRIEFFLRSSEKDMAPPPEECLQLISRATQVFREQYILKQDLAKEEIQRRVKLLCDQKKKQLEDLNYCREERKSLREMAERLADKYEEAKEKQEDIMNRMKKVLHSFHSQLPVLSDSERDMKKELQLIPDQLRHLGNAIKQVTMKKDYQQRKMEKVLSPQKPTITLSAYQRKCIQSILKEEGEHIREMVKQINDIRNHVNF", "length": 754, "header": "tr|F6R672-1|F6R672_BOVIN Isoform 1 of Nucleoporin 88 OS=Bos taurus OX=9913 GN=NUP88 PE=4 SV=1 CANONICAL=F6R672-1" }, "locus": { "chromosome": "19", "start_pos": 26149453, "end_pos": 26128027, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000001625.7", "url": "https://www.ensembl.org/id/ENSBTAT00000001625.7" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000001625.5", "url": "https://www.ensembl.org/id/ENSBTAP00000001625.5" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [], "orthologs": [], "go_annotation": { "categories": [ { "name": "Biological Process", "total": 4, "go_terms": [ { "name": "ribosomal large subunit export from nucleus", "id": "GO:0000055", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000055", "evidence": [ { "database": "UniProtKB", "id": "F6R672", "url": "https://www.uniprot.org/uniprotkb/F6R672" } ], "pmid": "" }, { "name": "protein transport", "id": "GO:0015031", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0015031", "evidence": [ { "database": "UniProtKB", "id": "F6R672", "url": "https://www.uniprot.org/uniprotkb/F6R672" } ], "pmid": "" }, { "name": "mRNA transport", "id": "GO:0051028", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0051028", "evidence": [ { "database": "UniProtKB", "id": "F6R672", "url": "https://www.uniprot.org/uniprotkb/F6R672" } ], "pmid": "" }, { "name": "ribosomal small subunit export from nucleus", "id": "GO:0000056", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000056", "evidence": [ { "database": "UniProtKB", "id": "F6R672", "url": "https://www.uniprot.org/uniprotkb/F6R672" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 1, "go_terms": [ { "name": "nuclear pore", "id": "GO:0005643", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005643", "evidence": [ { "database": "UniProtKB", "id": "F6R672", "url": "https://www.uniprot.org/uniprotkb/F6R672" } ], "pmid": "" } ] }, { "name": "Molecular Function", "total": 1, "go_terms": [ { "name": "structural constituent of nuclear pore", "id": "GO:0017056", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0017056", "evidence": [ { "database": "UniProtKB", "id": "F6R672", "url": "https://www.uniprot.org/uniprotkb/F6R672" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 155, "end_pos": 157, "annotation": "n_glycosylation_sequon" }, { "start_pos": 33, "end_pos": 35, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 155, "end_pos": 157 }, { "start_pos": 33, "end_pos": 35 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ], "tool_support": { "graph_view": "yes" } }, { "uniprot_canonical_ac": "F1N7H0-1", "uniprot_ac": "F1N7H0", "uniprot_id": "F1N7H0_BOVIN", "mass": { "chemical_mass": 56638.0, "monoisotopic_mass": 56638.0 }, "refseq": {}, "gene_names": [ { "name": "DNAJC7", "type": "recommended", "evidence": [ { "id": "F1N7H0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1N7H0" } ] } ], "protein_names": [ { "name": "DnaJ homolog subfamily C member 7", "type": "recommended", "evidence": [ { "id": "F1N7H0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1N7H0/entry#names_and_taxonomy" } ] } ], "function": [ { "annotation": "Acts as a co-chaperone regulating the molecular chaperones HSP70 and HSP90 in folding of steroid receptors, such as the glucocorticoid receptor and the progesterone receptor. Proposed to act as a recycling chaperone by facilitating the return of chaperone substrates to early stages of chaperoning if further folding is required. In vitro, induces ATP-independent dissociation of HSP90 but not of HSP70 from the chaperone-substrate complexes. Recruits NR1I3 to the cytoplasm.", "evidence": [ { "database": "UniProtKB", "id": "A0AAA9T3B7", "url": "https://www.uniprot.org/uniprotkb/A0AAA9T3B7#function" }, { "database": "UniProtKB", "id": "ARBA00053178", "url": "https://www.uniprot.org/uniprotkb/ARBA00053178#function" }, { "database": "UniProtKB", "id": "A0AAA9TGS0", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TGS0#function" }, { "database": "UniProtKB", "id": "F1N7H0", "url": "https://www.uniprot.org/uniprotkb/F1N7H0#function" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Bos taurus", "taxid": 9913, "evidence": [ { "database": "UniProtKB", "id": "F1N7H0", "url": "https://www.uniprot.org/uniprotkb/F1N7H0" } ], "common_name": "Bovine", "glygen_name": "Bovine", "reference_species": "Bos taurus [9913]" } ], "gene": [ { "name": "DNAJC7", "url": "https://www.uniprot.org/uniprotkb/F1N7H0", "locus": { "chromosome": "19", "start_pos": 42139364, 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"database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR036869", "url": "https://www.ebi.ac.uk/interpro/entry/IPR036869", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "F1N7H0", "url": "https://www.orthodb.org/?gene=F1N7H0", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR45188", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR45188", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR45188:SF2", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR45188:SF2", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00226", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00226", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF13181", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF13181", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, 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"database": "AlphaFoldDB", "categories": [] }, { "id": "cd17078", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd17078", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "cd17079", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd17079", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "IPR000626", "url": "https://www.ebi.ac.uk/interpro/entry/IPR000626", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR022617", "url": "https://www.ebi.ac.uk/interpro/entry/IPR022617", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR029071", "url": "https://www.ebi.ac.uk/interpro/entry/IPR029071", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR052324", "url": "https://www.ebi.ac.uk/interpro/entry/IPR052324", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "PTHR47187", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR47187", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR47187:SF1", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR47187:SF1", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF11976", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF11976", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "A0AAA9T8E7", "url": "https://www.uniprot.org/uniprotkb/A0AAA9T8E7", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0AAA9T8E7-1", "url": "https://www.uniprot.org/uniprotkb/A0AAA9T8E7-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "F6QF17", "url": "https://www.uniprot.org/uniprotkb/F6QF17", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "F6QF17-1", "url": "https://www.uniprot.org/uniprotkb/F6QF17-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MAEPVRRPGRPRGGGGGRRARGSRGGRSRCPGAQRSPARHTLDSGLVDLVSDSDEDVLEVATARGAAAAAEVPLPESPVPAASRDDSDSDSEGADAEPGGAPRVLVRRRRRLLLDPGEAPAVPVYSEKVKSSLHLIPDNVSLLKLCPPEAEEEADVEDASSPHAVDFPCPSSPWKKKLRSKDGEEKKKMLLDQDTSPLPSPLPRTKSRKHTQALRKLREVNKRLQDLRSCLSPKQSQGQDHLSQEDEVVLVEGPSLPENSRLLPLKIRCRADLVRLPIRMSEPLKSVVDHMAARLGVSPSRILLLLGETELSPTATPRALKLGVADIIDCVVLASSPEAAETSPLLQLRVQGKEKHQTLEVSLPPDSPLKTLMSRYEEAMGLSGHKLSFFFDGTKLSGGLWLHPQGVLNFTALWDMEKVSPHLH", "length": 424, "header": "tr|F6QF17-1|F6QF17_BOVIN Isoform 1 of NFATC2-interacting protein OS=Bos taurus OX=9913 GN=NFATC2IP PE=4 SV=1 CANONICAL=F6QF17-1" }, "isoforms": [ { "isoform_ac": "A0AAA9T8E7-1", "url": "https://www.uniprot.org/uniprotkb/A0AAA9T8E7/entry", "sequence": { "sequence": "MKKSEPLKSVVDHMAARLGVSPSRILLLLGETELSPTATPRALKLGVADIIDCVVLASSPEAAETSPLLQLRVQGKEKHQTLEVSLPPDSPLKTLMSRYEEAMGLSGHKLSFFFDGTKLSGKELPADLGMESGDLIEVWG", "length": 140, "header": "tr|A0AAA9T8E7-1|F6QF17_BOVIN Computationally mapped isoform of NFATC2-interacting protein OS=Bos taurus OX=9913 GN=NFATC2IP PE=4 SV=2 CANONICAL=F6QF17-1" }, "locus": { "chromosome": "25", "start_pos": 25894768, "end_pos": 25886969, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000107817.1", "url": "https://www.ensembl.org/id/ENSBTAT00000107817.1" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000092129.1", "url": "https://www.ensembl.org/id/ENSBTAP00000092129.1" } ] } }, { "isoform_ac": "F6QF17-1", "url": "https://www.uniprot.org/uniprotkb/F6QF17/entry", "sequence": { "sequence": "MAEPVRRPGRPRGGGGGRRARGSRGGRSRCPGAQRSPARHTLDSGLVDLVSDSDEDVLEVATARGAAAAAEVPLPESPVPAASRDDSDSDSEGADAEPGGAPRVLVRRRRRLLLDPGEAPAVPVYSEKVKSSLHLIPDNVSLLKLCPPEAEEEADVEDASSPHAVDFPCPSSPWKKKLRSKDGEEKKKMLLDQDTSPLPSPLPRTKSRKHTQALRKLREVNKRLQDLRSCLSPKQSQGQDHLSQEDEVVLVEGPSLPENSRLLPLKIRCRADLVRLPIRMSEPLKSVVDHMAARLGVSPSRILLLLGETELSPTATPRALKLGVADIIDCVVLASSPEAAETSPLLQLRVQGKEKHQTLEVSLPPDSPLKTLMSRYEEAMGLSGHKLSFFFDGTKLSGGLWLHPQGVLNFTALWDMEKVSPHLH", "length": 424, "header": "tr|F6QF17-1|F6QF17_BOVIN Isoform 1 of NFATC2-interacting protein OS=Bos taurus OX=9913 GN=NFATC2IP PE=4 SV=1 CANONICAL=F6QF17-1" }, "locus": { "chromosome": "25", "start_pos": 25897038, "end_pos": 25886674, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000019507.6", "url": "https://www.ensembl.org/id/ENSBTAT00000019507.6" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000019507.5", "url": "https://www.ensembl.org/id/ENSBTAP00000019507.5" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [], "orthologs": [], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 1, "go_terms": [ { "name": "nucleus", "id": "GO:0005634", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005634", "evidence": [ { "database": "UniProtKB", "id": "F6QF17", "url": "https://www.uniprot.org/uniprotkb/F6QF17" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 139, "end_pos": 141, "annotation": "n_glycosylation_sequon" }, { "start_pos": 409, "end_pos": 411, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "F6QF17", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F6QF17" }, { "id": "SM00213", "database": "SMART", "url": "http://smart.embl.de/smart/do_annotation.pl?DOMAIN=SM00213" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "Ubiquitin-like", "eco_id": "ECO_0000259", "start_pos": 263, "end_pos": 333, "start_aa": "Leu", "end_aa": "Leu", "glycosite_overlap": [] } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 139, "end_pos": 141 }, { "start_pos": 409, "end_pos": 411 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ], "tool_support": { "graph_view": "yes" } }, { "uniprot_canonical_ac": "F6PZT6-1", "uniprot_ac": "F6PZT6", "uniprot_id": "F6PZT6_BOVIN", "mass": { "chemical_mass": 48973.0, "monoisotopic_mass": 48973.0 }, "refseq": { "ac": "XP_005215881", "name": "transmembrane protease serine 4 isoform X1", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_005215881" }, "gene_names": [ { "name": "TMPRSS4", "type": "recommended", "evidence": [ { "id": "F6PZT6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F6PZT6" } ] }, { "name": "TMPRSS4", "type": "synonym", "evidence": [ { "id": "XP_005215881", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_005215881" } ] } ], "protein_names": [ { "name": "Transmembrane serine protease 4", "type": "synonym", "evidence": [ { "id": "F6PZT6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F6PZT6/entry#names_and_taxonomy" } ] }, { "name": "transmembrane protease serine 4 isoform X1", "type": "synonym", "evidence": [ { "id": "XP_005215881", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_005215881" } ] } ], "function": [], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Bos taurus", "taxid": 9913, "evidence": [ { "database": "UniProtKB", "id": "F6PZT6", "url": "https://www.uniprot.org/uniprotkb/F6PZT6" } ], "common_name": "Bovine", "glygen_name": "Bovine", "reference_species": "Bos taurus [9913]" } ], "gene": [ { "name": "TMPRSS4", "url": "https://www.uniprot.org/uniprotkb/F6PZT6", "locus": { "chromosome": "15", "start_pos": 28801593, "end_pos": 28761713, "strand": "-", "evidence": [ { "database": "Ensembl Gene", "id": "ENSBTAG00000021518", "url": "https://www.ensembl.org/id/ENSBTAG00000021518" } ] } } ], "crossref": [ { "id": "F6PZT6", "url": "https://alphafold.ebi.ac.uk/entry/F6PZT6", "database": "AlphaFoldDB", "categories": [] }, { "id": "ENSBTAG00000021518", "url": "https://bgee.org/?page=gene&gene_id=ENSBTAG00000021518", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "cd00112", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd00112", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "cd00190", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd00190", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "513343", "url": "https://www.ncbi.nlm.nih.gov/gene/513343", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR001190", "url": "https://www.ebi.ac.uk/interpro/entry/IPR001190", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR001254", "url": "https://www.ebi.ac.uk/interpro/entry/IPR001254", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR001314", "url": "https://www.ebi.ac.uk/interpro/entry/IPR001314", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR002172", "url": "https://www.ebi.ac.uk/interpro/entry/IPR002172", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR009003", "url": "https://www.ebi.ac.uk/interpro/entry/IPR009003", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR018114", "url": "https://www.ebi.ac.uk/interpro/entry/IPR018114", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR033116", "url": "https://www.ebi.ac.uk/interpro/entry/IPR033116", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR036055", "url": "https://www.ebi.ac.uk/interpro/entry/IPR036055", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR036772", "url": "https://www.ebi.ac.uk/interpro/entry/IPR036772", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR043504", "url": "https://www.ebi.ac.uk/interpro/entry/IPR043504", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "GNWASAC", "url": "https://omabrowser.org/oma/group/GNWASAC/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "F6PZT6", "url": "https://www.orthodb.org/?gene=F6PZT6", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR24252", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR24252", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR24252:SF17", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR24252:SF17", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00057", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00057", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF00089", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00089", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF15494", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF15494", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "XP_005215881", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_005215881", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0AAA9T8M4", "url": "https://www.uniprot.org/uniprotkb/A0AAA9T8M4", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0AAA9T8M4-1", "url": "https://www.uniprot.org/uniprotkb/A0AAA9T8M4-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "F6PZT6", "url": "https://www.uniprot.org/uniprotkb/F6PZT6", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "F6PZT6-1", "url": "https://www.uniprot.org/uniprotkb/F6PZT6-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MENSEDRRARVDPEINRPLNSLDVTPLRKSRTPLEIFKKVGIPIIAAVLILATIIVVAVLIKVILDSYFFFCGQPLLFIPREQVCDGHQDCASGEDEKYCVKKLPDGPPVAVRLSRDRSTLQVLNPATKNWASACFDSFTEALAKTACRQMGYDSSKPTFRAVDAGPAQDLDIVKVTENLQELQVQNSSGPCLSGSLVSLQCLACGQSVKAPRVVGGKEASVDSWPWQVSIQYDKQHICGGSILDPHWILTAAHCFWKHLDVPNWKVRAGSDRLGSFPSLPVAKIFILEPNATYPREHDIALVKLQLPLTFSGTIRPICLPFSDEELTPGTPLWVIGWGFTEENGGKMSDILQQGSVQLINRTRCNAEDAYQGEVTKTMMCAGLPEGGVDTCQGDSGGPLMYHSDWWQVVGIVSWGHGCGGPTTPGVYTKVTAYLNWIYNVRKSDP", "length": 446, "header": "tr|F6PZT6-1|F6PZT6_BOVIN Isoform 1 of Transmembrane serine protease 4 OS=Bos taurus OX=9913 GN=TMPRSS4 PE=4 SV=1 CANONICAL=F6PZT6-1" }, "isoforms": [ { "isoform_ac": "A0AAA9T8M4-1", "url": "https://www.uniprot.org/uniprotkb/A0AAA9T8M4/entry", "sequence": { "sequence": "MENSEDRRARVDPEINRPLNSLVKVILDSYFFFCGQPLLFIPREQVCDGHQDCASGEDEKYCVKKLPDGPPVAVRLSRDRSTLQVLNPATKNWASACFDSFTEALAKTACRQMGYDSKPTFRAVDAGPAQDLDIVKVTENLQELQVQNSSGPCLSGSLVSLQCLACGQSVKAPRVVGGKEASVDSWPWQVSIQYDKQHICGGSILDPHWILTAAHCFWKHLDVPNWKVRAGSDRLGSFPSLPVAKIFILEPNATYPREHDIALVKLQLPLTFSGTIRPICLPFSDEELTPGTPLWVIGWGFTEENGGKMSDILQQGSVQLINRTRCNAEDAYQGEVTKTMMCAGLPEGGVDTCQGDSGGPLMYHSDWWQVVGIVSWGHGCGGPTTPGVYTKVTAYLNWIYNVRKSDP", "length": 407, "header": "tr|A0AAA9T8M4-1|F6PZT6_BOVIN Computationally mapped isoform of Transmembrane serine protease 4 OS=Bos taurus OX=9913 GN=TMPRSS4 PE=4 SV=1 CANONICAL=F6PZT6-1" }, "locus": { "chromosome": "15", "start_pos": 28801045, "end_pos": 28761916, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000108407.1", "url": "https://www.ensembl.org/id/ENSBTAT00000108407.1" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000092225.1", "url": "https://www.ensembl.org/id/ENSBTAP00000092225.1" } ] } }, { "isoform_ac": "F6PZT6-1", "url": "https://www.uniprot.org/uniprotkb/F6PZT6/entry", "sequence": { "sequence": "MENSEDRRARVDPEINRPLNSLDVTPLRKSRTPLEIFKKVGIPIIAAVLILATIIVVAVLIKVILDSYFFFCGQPLLFIPREQVCDGHQDCASGEDEKYCVKKLPDGPPVAVRLSRDRSTLQVLNPATKNWASACFDSFTEALAKTACRQMGYDSSKPTFRAVDAGPAQDLDIVKVTENLQELQVQNSSGPCLSGSLVSLQCLACGQSVKAPRVVGGKEASVDSWPWQVSIQYDKQHICGGSILDPHWILTAAHCFWKHLDVPNWKVRAGSDRLGSFPSLPVAKIFILEPNATYPREHDIALVKLQLPLTFSGTIRPICLPFSDEELTPGTPLWVIGWGFTEENGGKMSDILQQGSVQLINRTRCNAEDAYQGEVTKTMMCAGLPEGGVDTCQGDSGGPLMYHSDWWQVVGIVSWGHGCGGPTTPGVYTKVTAYLNWIYNVRKSDP", "length": 446, "header": "tr|F6PZT6-1|F6PZT6_BOVIN Isoform 1 of Transmembrane serine protease 4 OS=Bos taurus OX=9913 GN=TMPRSS4 PE=4 SV=1 CANONICAL=F6PZT6-1" }, "locus": { "chromosome": "15", "start_pos": 28801045, "end_pos": 28761916, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000028678.7", "url": "https://www.ensembl.org/id/ENSBTAT00000028678.7" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000028678.5", "url": "https://www.ensembl.org/id/ENSBTAP00000028678.5" } ] } } ], "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "other", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 423, "start_aa": "Thr", "end_pos": 423, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr423", "evidence": [ { "id": "", "database": "GlyGen", "url": "https://data.glygen.org/" } ], "filter_code": "000000000000000010000.00000000001000.0.01000" } ], "phosphorylation": [], "glycation": [], "keywords": [ "glycoprotein", "glycoprotein_predicted" ], "publication": [], "pathway": [], "orthologs": [ { "uniprot_canonical_ac": "A0A4X1STB8-1", "protein_name": "Transmembrane serine protease 4", "gene_name": "TMPRSS4", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MDPASDQPLNSLDVAPQRKPRTPLQTFKKVGIPIIAALLGLAAIVVVAILIKVILDKYYFLCWQPLHFIPREQLCDGQQDCASGEDEQLCVKKFPDGPPVAVRLSRDRSTLQVLHPATQTWASACFDNFTEALAKTACGQMGYDSKPTFRAVRIGPDQDLDVVKITENDQELRVQNSSGPCLSGSLVSLHCLACGESLKAPRVVGGEKASVDSWPWQVSIQYNKQHICGGSILDPHWILTAAHCFWKHLDVPNWKVRAGSDKLGNFPSLPVAKIFITEPNSTSPKEKDIALVKLQLPLTFSGTVRPICLPFSDEELTPGTPVWVIGWGFTEPNGGKMSDHLLQASVQVINRTRCNAEDAYQGEVTEKMLCAGLLEGGVDTCQGDSGGPLMYHSGRWQAVGIVSWGYGCGGPSTPGVYTKVTAYLDWIYNVRKSDP", "length": 435 }, "evidence": [ { "id": "F6PZT6", "url": "https://omabrowser.org/oma/group/F6PZT6/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "A0A8V0ZX70-1", "protein_name": "Transmembrane serine protease 4", "gene_name": "TMPRSS4", "tax_id": 9031, "organism": "Gallus gallus", "sequence": { "sequence": "MDPASERLNGEEPGTRHKASGAQHSWKRIGIPILVTVLVLACLAAVGLLVKVYLEHHYFICKQPLKLVPLAQVCNGEADCLHGEDETSCPQQVPEGPQAAARLSKDRSILQVLNRNTGAWSCVCSDYFSPALAKAACEEMGYSSTPTFHAVDAGAGQPLPPRELVLSNGRLQLPEPGRKCLSGSVVSLLCSSCGESVRTPRVLGGRPAAIEAWPWQVSLRYRGEHICGGSIIDPLWILTAAHCFRNNPIIPSWRVKAGSDVLSGPANLAVEKVFLAEGTPTSPNNNDIALVKLQIPLHISDSTKPICLPYFDEELEPDTPLWVIGWGYTQQNGKLSEALQQAEVRLISMQSCNLQAYHGKVTQKMLCAGLLEGGVDTCQVRGSTGCPTTLGVPAPELGQVVLWNGPVEGMRARRDAHSQRWSLAGGQRRASAVCKQALAGGGHRQLGLRLRHPQHTRCLHQRPSVPRLDLRRPQVGALRPARTSVLCQRPDEEAKGGSGSGHSLGMHPAGAPFQREINLLPCADPAVSGSTLLFAHYCFTEINDVCALVYRL", "length": 552 }, "evidence": [ { "id": "F6PZT6", "url": "https://omabrowser.org/oma/group/F6PZT6/", "database": "OMA" } ], "glygen_name": "Chicken", "common_name": "Chicken" }, { "uniprot_canonical_ac": "D3Z9X4-1", "protein_name": "Transmembrane protease serine 4", "gene_name": "Tmprss4", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MEPDSGQPLNNHDVPPFRKPRSPLETFKKVGIPIIAVILSLIALGIVALLIKVVLDKYYFICGNPLTFIPRGQMCDGHLDCASGEDEEHCVKNFPEKPGVTVRLSKDRSTLQVLDAARGTWASVCFDNFTEALAKTACRQMGYNSQPAFGPVEMGPNQTLLVTPVTGNSQELQMQNGSRSCLSGSLVSLRCLDCGKSLKTTRVVGGVEASADSWPWQVSIQYNKQHVCGGSILDHHWILTAAHCFRKYLDVSSWKVRAGSNKLGNSPSLPVAKIFIAEPNPLQPKEKDIALVKLKMPLTFSGSVRPICLPFSDEELIPTMPVWVIGWGFTEENGGKMSDTLLQASVQVIDSARCNAEDAYQGEVTAGMLCAGTPQGGKDTCQGDSGGPLMYHYDKWQVVGIVSWGYGCGSPSTPGVYTKVTAYLDWIYNVRRSEM", "length": 435 }, "evidence": [ { "id": "F6PZT6", "url": "https://omabrowser.org/oma/group/F6PZT6/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "Q8VCA5-1", "protein_name": "Transmembrane protease serine 4", "gene_name": "Tmprss4", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MESDSGQPLNNRDIVPFRKPRRPQETFKKVGIPIIAVLLSLIALVIVALLIKVILDKYYFICGSPLTFIQRGQLCDGHLDCASGEDEEHCVKDFPEKPGVAVRLSKDRSTLQVLDAATGTWASVCFDNFTEALAKTACRQMGYDSQPAFRAVEIRPDQNLPVAQVTGNSQELQVQNGSRSCLSGSLVSLRCLDCGKSLKTPRVVGGVEAPVDSWPWQVSIQYNKQHVCGGSILDPHWILTAAHCFRKYLDVSSWKVRAGSNILGNSPSLPVAKIFIAEPNPLYPKEKDIALVKLQMPLTFSGSVRPICLPFSDEVLVPATPVWVIGWGFTEENGGKMSDMLLQASVQVIDSTRCNAEDAYEGEVTAEMLCAGTPQGGKDTCQGDSGGPLMYHSDKWQVVGIVSWGHGCGGPSTPGVYTKVTAYLNWIYNVRKSEM", "length": 435 }, "evidence": [ { "id": "F6PZT6", "url": "https://omabrowser.org/oma/group/F6PZT6/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q9NRS4-1", "protein_name": "Transmembrane protease serine 4", "gene_name": "TMPRSS4", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MLQDPDSDQPLNSLDVKPLRKPRIPMETFRKVGIPIIIALLSLASIIIVVVLIKVILDKYYFLCGQPLHFIPRKQLCDGELDCPLGEDEEHCVKSFPEGPAVAVRLSKDRSTLQVLDSATGNWFSACFDNFTEALAETACRQMGYSSKPTFRAVEIGPDQDLDVVEITENSQELRMRNSSGPCLSGSLVSLHCLACGKSLKTPRVVGVEEASVDSWPWQVSIQYDKQHVCGGSILDPHWVLTAAHCFRKHTDVFNWKVRAGSDKLGSFPSLAVAKIIIIEFNPMYPKDNDIALMKLQFPLTFSGTVRPICLPFFDEELTPATPLWIIGWGFTKQNGGKMSDILLQASVQVIDSTRCNADDAYQGEVTEKMMCAGIPEGGVDTCQGDSGGPLMYQSDQWHVVGIVSWGYGCGGPSTPGVYTKVSAYLNWIYNVWKAEL", "length": 437 }, "evidence": [ { "id": "F6PZT6", "url": "https://omabrowser.org/oma/group/F6PZT6/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" } ], "go_annotation": { "categories": [ { "name": "Molecular Function", "total": 2, "go_terms": [ { "name": "serine-type endopeptidase activity", "id": "GO:0004252", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0004252", "evidence": [ { "database": "UniProtKB", "id": "F6PZT6", "url": "https://www.uniprot.org/uniprotkb/F6PZT6" } ], "pmid": "" }, { "name": "serine-type peptidase activity", "id": "GO:0008236", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008236", "evidence": [ { "database": "UniProtKB", "id": "F6PZT6", "url": "https://www.uniprot.org/uniprotkb/F6PZT6" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 2, "go_terms": [ { "name": "proteolysis", "id": "GO:0006508", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006508", "evidence": [ { "database": "UniProtKB", "id": "F6PZT6", "url": "https://www.uniprot.org/uniprotkb/F6PZT6" } ], "pmid": "" }, { "name": "protein processing", "id": "GO:0016485", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016485", "evidence": [ { "database": "UniProtKB", "id": "F6PZT6", "url": "https://www.uniprot.org/uniprotkb/F6PZT6" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 2, "go_terms": [ { "name": "membrane", "id": "GO:0016020", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016020", "evidence": [ { "database": "UniProtKB", "id": "F6PZT6", "url": "https://www.uniprot.org/uniprotkb/F6PZT6" } ], "pmid": "" }, { "name": "secretory granule", "id": "GO:0030141", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030141", "evidence": [ { "database": "UniProtKB", "id": "F6PZT6", "url": "https://www.uniprot.org/uniprotkb/F6PZT6" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 187, "end_pos": 189, "annotation": "n_glycosylation_sequon" }, { "start_pos": 291, "end_pos": 293, "annotation": "n_glycosylation_sequon" }, { "start_pos": 361, "end_pos": 363, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [ { "pdb_id": "AF-F6PZT6-F1", "pdb_chain": "global", "start_pos": 1, "end_pos": 446, "overlap": "1.0", "method": "AlphaFold", "type": "alphafold", "resolution": -1.0, "url": "https://data.glygen.org/ln2downloads/pdb/current/AF-F6PZT6-F1.pdb", "url_external": "https://alphafold.ebi.ac.uk/entry/F6PZT6" } ], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "F6PZT6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F6PZT6" }, { "id": "PS50240", "database": "PROSITE", "url": "https://prosite.expasy.org/PS50240" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "Peptidase S1", "eco_id": "ECO_0000259", "start_pos": 214, "end_pos": 443, "start_aa": "Val", "end_aa": "Lys", "glycosite_overlap": [] }, { "evidence": [ { "id": "F6PZT6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F6PZT6" }, { "id": "PS50287", "database": "PROSITE", "url": "https://prosite.expasy.org/PS50287" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "SRCR", "eco_id": "ECO_0000259", "start_pos": 102, "end_pos": 152, "start_aa": "Lys", "end_aa": "Gly", "glycosite_overlap": [] } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" }, { "name": "homologset.oma", "label": "OMA Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [ 423 ], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 187, "end_pos": 189 }, { "start_pos": 291, "end_pos": 293 }, { "start_pos": 361, "end_pos": 363 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 1 }, { "field": "total_sites", "count": 1 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 1 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "exact_sites", "count": 1 }, { "field": "exact_o_linked_sites", "count": 1 }, { "field": "fuzzy_sites", "count": 0 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_pos", "start_aa", "end_pos", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 1 }, { "field": "total_sites", "count": 1 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 1 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "exact_sites", "count": 1 }, { "field": "exact_o_linked_sites", "count": 1 }, { "field": "fuzzy_sites", "count": 0 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_pos", "start_aa", "end_pos", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ], "tool_support": { "graph_view": "yes" } }, { "uniprot_canonical_ac": "F6Q2S9-1", "uniprot_ac": "F6Q2S9", "uniprot_id": "F6Q2S9_BOVIN", "mass": { "chemical_mass": 65010.0, "monoisotopic_mass": 65010.0 }, "refseq": {}, "gene_names": [ { "name": "ZNF565", "type": "recommended", "evidence": [ { "id": "F6Q2S9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F6Q2S9" } ] } ], "protein_names": [ { "name": "Zinc finger protein 565", "type": "synonym", "evidence": [ { "id": "F6Q2S9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F6Q2S9/entry#names_and_taxonomy" } ] } ], "function": [ { "annotation": "May be involved in transcriptional regulation.", "evidence": [ { "database": "UniProtKB", "id": "A0AAA9TAE5", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TAE5#function" }, { "database": "UniProtKB", "id": "ARBA00003767", "url": "https://www.uniprot.org/uniprotkb/ARBA00003767#function" }, { "database": "UniProtKB", "id": "A0AAA9TXG1", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TXG1#function" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Bos taurus", "taxid": 9913, "evidence": [ { "database": "UniProtKB", "id": "F6Q2S9", "url": "https://www.uniprot.org/uniprotkb/F6Q2S9" } ], "common_name": "Bovine", "glygen_name": "Bovine", "reference_species": "Bos taurus [9913]" } ], "gene": [ { "name": "ZNF565", "url": "https://www.uniprot.org/uniprotkb/F6Q2S9", "locus": { "chromosome": "18", "start_pos": 46829855, "end_pos": 46855952, "strand": "+", "evidence": [ { "database": "Ensembl Gene", "id": "ENSBTAG00000009521", "url": "https://www.ensembl.org/id/ENSBTAG00000009521" } ] } } ], "crossref": [ { "id": "F6Q2S9", "url": "https://alphafold.ebi.ac.uk/entry/F6Q2S9", "database": "AlphaFoldDB", "categories": [] }, { "id": "cd07765", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd07765", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "IPR001909", "url": "https://www.ebi.ac.uk/interpro/entry/IPR001909", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR013087", "url": "https://www.ebi.ac.uk/interpro/entry/IPR013087", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR036051", "url": "https://www.ebi.ac.uk/interpro/entry/IPR036051", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR036236", "url": "https://www.ebi.ac.uk/interpro/entry/IPR036236", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR050527", "url": "https://www.ebi.ac.uk/interpro/entry/IPR050527", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR050752", "url": "https://www.ebi.ac.uk/interpro/entry/IPR050752", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "PTHR14003", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR14003", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR14003:SF23", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR14003:SF23", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR24384", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR24384", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR24384:SF235", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR24384:SF235", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR24388", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR24388", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR24388:SF96", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR24388:SF96", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00096", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00096", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF01352", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF01352", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "A0AAA9TAE5", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TAE5", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0AAA9TAE5-1", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TAE5-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0AAA9TXG1", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TXG1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0AAA9TXG1-1", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TXG1-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "F6Q2S9", "url": "https://www.uniprot.org/uniprotkb/F6Q2S9", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "F6Q2S9-1", "url": "https://www.uniprot.org/uniprotkb/F6Q2S9-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MPPALAGIFFTTTTTWEAQTFSELQDQTSNGHLVFPLGCIIIISRIDVKGLFTCSTEESKEIQAGQVVLKAMIQGLVTFRDVAIEFSQEEWKYLEPAQRDLYREVTLENFGNLVSLGLSISKPDVVSLLEQGKEPWMVVNDMTGPWCPDLESRCKTFLQKDTFEVMSFNWELMESLQCYGEDWAYKGQFEKQQVNHECCFKQVKITYGNMPTFECGHTSLTLHPSSETGEKSIECNECGKAFSRGSHLIQHQKTHTGEKPFECKECGKAFSRTSHLVQHQRIHTGEKPYDCKECGKAFGRTSELILHQRLHTGVKPYECKECGKTFRQHSQLILHHRTHTGEKPYVCKDCGKAFIRGSQLTVHRRIHTGARPYQCKECGKAFRQHSQLTVHQRIHTGEKPYECKECGKGFIHSSEVTRHQRIHSGEKPYECKECGKAFRQHAQLTRHQRVHTGDRPYECKDCGKAFSRSSYLIQHQRIHTGDKPYECKECGKAFIRVSQLTHHQRIHTCEKPYQCRECGMAFIRSSQLTEHQRIHPGIKPYECRECGQAFILGSQLIEHYRIHTG", "length": 565, "header": "tr|F6Q2S9-1|F6Q2S9_BOVIN Isoform 1 of Zinc finger protein 565 OS=Bos taurus OX=9913 GN=ZNF565 PE=3 SV=1 CANONICAL=F6Q2S9-1" }, "isoforms": [ { "isoform_ac": "A0AAA9TAE5-1", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TAE5/entry", "sequence": { "sequence": "LFTCSTEESKEIQAGQVVLKAMIQGLVTFRDVAIEFSQEEWKYLEPAQRDLYREVTLENFGNLVSLGLSISKPDVVSLLEQGKEPWMVVNDMTGPWCPDLESRCKTFLQKDTFEVMSFNWELMESLQCYGEDWAYKGQFEKQQVNHECCFKQVKITYGNMPTFECGHTSLTLHPSSETGEKSIECNECGKAFSRGSHLIQHQKTHTGEKPFECKECGKAFSRTSHLVQHQRIHTGEKPYDCKECGKAFGRTSELILHQRLHTGVKPYECKECGKTFRQHSQLILHHRTHTGEKPYVCKDCGKAFIRGSQLTVHRRIHTGARPYQCKECGKAFRQHSQLTVHQRIHTGEKPYECKECGKGFIHSSEVTRHQRIHSGEKPYECKECGKAFRQHAQLTRHQRVHTGDRPYECKDCGKAFSRSSYLIQHQRIHTGDKPYECKECGKAFIRVSQLTHHQRIHTCEKPYQCRECGMAFIRSSQLTEHQRIHPGIKPYECRECGQAFILGSQLIEHYRIHTG", "length": 515, "header": "tr|A0AAA9TAE5-1|F6Q2S9_BOVIN Computationally mapped isoform of Zinc finger protein 565 OS=Bos taurus OX=9913 GN=ZNF565 PE=3 SV=1 CANONICAL=F6Q2S9-1" }, "locus": { "chromosome": "18", "start_pos": 46842647, "end_pos": 46830041, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000123429.2", "url": "https://www.ensembl.org/id/ENSBTAT00000123429.2" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000093599.1", "url": "https://www.ensembl.org/id/ENSBTAP00000093599.1" } ] } }, { "isoform_ac": "A0AAA9TXG1-1", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TXG1/entry", "sequence": { "sequence": "MRCAPSPPYSVFSGLFTCSTEESKEIQAGQVVLKAMIQGLVTFRDVAIEFSQEEWKYLEPAQRDLYREVTLENFGNLVSLGLSISKPDVVSLLEQGKEPWMVVNDMTGPWCPDLESRCKTFLQKDTFEVMSFNWELMESLQCYGEDWAYKGQFEKQQVNHECCFKQVKITYGNMPTFECGHTSLTLHPSSETGEKSIECNECGKAFSRGSHLIQHQKTHTGEKPFECKECGKAFSRTSHLVQHQRIHTGEKPYDCKECGKAFGRTSELILHQRLHTGVKPYECKECGKTFRQHSQLILHHRTHTGEKPYVCKDCGKAFIRGSQLTVHRRIHTGARPYQCKECGKAFRQHSQLTVHQRIHTGEKPYECKECGKGFIHSSEVTRHQRIHSGEKPYECKECGKAFRQHAQLTRHQRVHTGDRPYECKDCGKAFSRSSYLIQHQRIHTGDKPYECKECGKAFIRVSQLTHHQRIHTCEKPYQCRECGMAFIRSSQLTEHQRIHPGIKPYECRECGQAFILGSQLIEHYRIHTG", "length": 529, "header": "tr|A0AAA9TXG1-1|A0AAA9TXG1_BOVIN Computationally mapped isoform of Zinc finger protein 565 OS=Bos taurus OX=9913 GN=ZNF565 PE=3 SV=1 CANONICAL=F6Q2S9-1" }, "locus": { "chromosome": "18", "start_pos": 46842689, "end_pos": 46830041, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000097952.1", "url": "https://www.ensembl.org/id/ENSBTAT00000097952.1" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000101333.1", "url": "https://www.ensembl.org/id/ENSBTAP00000101333.1" } ] } }, { "isoform_ac": "F6Q2S9-1", "url": "https://www.uniprot.org/uniprotkb/F6Q2S9/entry", "sequence": { "sequence": "MPPALAGIFFTTTTTWEAQTFSELQDQTSNGHLVFPLGCIIIISRIDVKGLFTCSTEESKEIQAGQVVLKAMIQGLVTFRDVAIEFSQEEWKYLEPAQRDLYREVTLENFGNLVSLGLSISKPDVVSLLEQGKEPWMVVNDMTGPWCPDLESRCKTFLQKDTFEVMSFNWELMESLQCYGEDWAYKGQFEKQQVNHECCFKQVKITYGNMPTFECGHTSLTLHPSSETGEKSIECNECGKAFSRGSHLIQHQKTHTGEKPFECKECGKAFSRTSHLVQHQRIHTGEKPYDCKECGKAFGRTSELILHQRLHTGVKPYECKECGKTFRQHSQLILHHRTHTGEKPYVCKDCGKAFIRGSQLTVHRRIHTGARPYQCKECGKAFRQHSQLTVHQRIHTGEKPYECKECGKGFIHSSEVTRHQRIHSGEKPYECKECGKAFRQHAQLTRHQRVHTGDRPYECKDCGKAFSRSSYLIQHQRIHTGDKPYECKECGKAFIRVSQLTHHQRIHTCEKPYQCRECGMAFIRSSQLTEHQRIHPGIKPYECRECGQAFILGSQLIEHYRIHTG", "length": 565, "header": "tr|F6Q2S9-1|F6Q2S9_BOVIN Isoform 1 of Zinc finger protein 565 OS=Bos taurus OX=9913 GN=ZNF565 PE=3 SV=1 CANONICAL=F6Q2S9-1" }, "locus": { "chromosome": "18", "start_pos": 46847485, "end_pos": 46830041, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000012529.6", "url": "https://www.ensembl.org/id/ENSBTAT00000012529.6" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000012529.5", "url": "https://www.ensembl.org/id/ENSBTAP00000012529.5" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [], "orthologs": [], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 1, "go_terms": [ { "name": "nucleus", "id": "GO:0005634", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005634", "evidence": [ { "database": "UniProtKB", "id": "F6Q2S9", "url": "https://www.uniprot.org/uniprotkb/F6Q2S9" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 2, "go_terms": [ { "name": "DNA-templated transcription", "id": "GO:0006351", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006351", "evidence": [ { "database": "UniProtKB", "id": "F6Q2S9", "url": "https://www.uniprot.org/uniprotkb/F6Q2S9" } ], "pmid": "" }, { "name": "regulation of DNA-templated transcription", "id": "GO:0006355", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006355", "evidence": [ { "database": "UniProtKB", "id": "F6Q2S9", "url": "https://www.uniprot.org/uniprotkb/F6Q2S9" } ], "pmid": "" } ] }, { "name": "Molecular Function", "total": 2, "go_terms": [ { "name": "zinc ion binding", "id": "GO:0008270", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008270", "evidence": [ { "database": "UniProtKB", "id": "F6Q2S9", "url": "https://www.uniprot.org/uniprotkb/F6Q2S9" } ], "pmid": "" }, { "name": "sequence-specific double-stranded DNA binding", "id": "GO:1990837", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:1990837", "evidence": [ { "database": "UniProtKB", "id": "F6Q2S9", "url": "https://www.uniprot.org/uniprotkb/F6Q2S9" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "F6Q2S9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F6Q2S9" }, { "id": "PS50157", "database": "PROSITE", "url": "https://prosite.expasy.org/PS50157" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "C2H2-type", "eco_id": "ECO_0000259", "start_pos": 233, "end_pos": 260, "start_aa": "Ile", "end_aa": "Pro", "glycosite_overlap": [] }, { "evidence": [ { "id": "F6Q2S9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F6Q2S9" }, { "id": "PS50805", "database": "PROSITE", "url": "https://prosite.expasy.org/PS50805" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "KRAB", "eco_id": "ECO_0000259", "start_pos": 77, "end_pos": 148, "start_aa": "Val", "end_aa": "Pro", "glycosite_overlap": [] } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ], "tool_support": { "graph_view": "yes" } }, { "uniprot_canonical_ac": "F1N591-1", "uniprot_ac": "F1N591", "uniprot_id": "F1N591_BOVIN", "mass": { "chemical_mass": 41786.0, "monoisotopic_mass": 41786.0 }, "refseq": {}, "gene_names": [ { "name": "LOC505773", "type": "recommended", "evidence": [ { "id": "F1N591", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1N591" } ] } ], "protein_names": [ { "name": "Protein kinase cAMP-dependent X-linked catalytic subunit", "type": "synonym", "evidence": [ { "id": "F1N591", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1N591/entry#names_and_taxonomy" } ] } ], "function": [], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Bos taurus", "taxid": 9913, "evidence": [ { "database": "UniProtKB", "id": "F1N591", "url": "https://www.uniprot.org/uniprotkb/F1N591" } ], "common_name": "Bovine", "glygen_name": "Bovine", "reference_species": "Bos taurus [9913]" } ], "gene": [ { "name": "LOC505773", "url": "https://www.uniprot.org/uniprotkb/F1N591", "locus": {} } ], "crossref": [ { "id": "ENSBTAG00000014367", "url": "https://bgee.org/?page=gene&gene_id=ENSBTAG00000014367", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "cd05612", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd05612", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "505773", "url": "https://www.ncbi.nlm.nih.gov/gene/505773", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR000719", "url": "https://www.ebi.ac.uk/interpro/entry/IPR000719", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR000961", "url": "https://www.ebi.ac.uk/interpro/entry/IPR000961", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR008271", "url": "https://www.ebi.ac.uk/interpro/entry/IPR008271", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR011009", "url": "https://www.ebi.ac.uk/interpro/entry/IPR011009", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR017441", "url": "https://www.ebi.ac.uk/interpro/entry/IPR017441", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "F1N591", "url": "https://www.orthodb.org/?gene=F1N591", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR24353", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR24353", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR24353:SF37", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR24353:SF37", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00069", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00069", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "A0AAA9TKM3", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TKM3", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0AAA9TKM3-1", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TKM3-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "F1N591", "url": "https://www.uniprot.org/uniprotkb/F1N591", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "F1N591-1", "url": "https://www.uniprot.org/uniprotkb/F1N591-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MEARALAEADAAGPREGPAEPTAGAPEPEPLAYRPDDFHMRATVGTGTFGRVQLVQEKTSKHFFALKVMTIPDIIRLKQEQHVHNEKSVLKEVNHPFLVKLFWTGHDDRFLYMLMEFVPGGELFSYLRNRGRFSSNTGLFYAAEIVCAIEYLHSRDIVYRDLKPENILLDRDGHVKLTDFGFAKKLVDKTWTLCGTPEYLAPEVIQSKGHGRAVDWWALGILIFEMLSGFPPFFDDNAFGIYQKILAGKIDFPRHLEFSVKDLIRKLLVTDRTRRLGNMKNGAEDVKQHRWFRVVDWGAVPERKLKSHGCSPPGSSVHGDSPRENTGPPIIPKLCSEDDTSNFEAYPENDWTSAPPVSQKELDVFKNF", "length": 368, "header": "tr|F1N591-1|F1N591_BOVIN Isoform 1 of Protein kinase cAMP-dependent X-linked catalytic subunit OS=Bos taurus OX=9913 GN=LOC505773 PE=3 SV=5 CANONICAL=F1N591-1" }, "isoforms": [ { "isoform_ac": "A0AAA9TKM3-1", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TKM3/entry", "sequence": { "sequence": "MEARALAEADAAGPREGPAEPTAGAPEPEPLAYRPDDFHMRATVGTGTFGRVQLVQEKTSKHFFALKVMTIPDIIRLKQEQHVHNEKSVLKEVNHPFLVKLFWTGHDDRFLYMLMEFVPGGELFSYLRNRGRFSSNTGLFYAAEIVCAIEYLHSRDIVYRDLKPENILLDRDGHVKLTDFGFAKKLVDKTWTLCGTPEYLAPEVIQSKGHGRAVDWWALGILIFEMLSGFPPFFDDNAFGIYQKILAGKIDFPRHLEFSVKDLIRKLLVTDRTRRLGNMKNGAEDVKQHRWFRVVDWGAVPERKLKPPIIPKLCSEDDTSNFEAYPENDWTSAPPVSQKELDVFKNF", "length": 347, "header": "tr|A0AAA9TKM3-1|F1N591_BOVIN Computationally mapped isoform of Protein kinase cAMP-dependent X-linked catalytic subunit OS=Bos taurus OX=9913 GN=LOC505773 PE=3 SV=1 CANONICAL=F1N591-1" }, "locus": { "chromosome": "Y", "start_pos": 1774729, "end_pos": 1721552, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000108768.2", "url": "https://www.ensembl.org/id/ENSBTAT00000108768.2" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000098944.1", "url": "https://www.ensembl.org/id/ENSBTAP00000098944.1" } ] } }, { "isoform_ac": "F1N591-1", "url": "https://www.uniprot.org/uniprotkb/F1N591/entry", "sequence": { "sequence": "MEARALAEADAAGPREGPAEPTAGAPEPEPLAYRPDDFHMRATVGTGTFGRVQLVQEKTSKHFFALKVMTIPDIIRLKQEQHVHNEKSVLKEVNHPFLVKLFWTGHDDRFLYMLMEFVPGGELFSYLRNRGRFSSNTGLFYAAEIVCAIEYLHSRDIVYRDLKPENILLDRDGHVKLTDFGFAKKLVDKTWTLCGTPEYLAPEVIQSKGHGRAVDWWALGILIFEMLSGFPPFFDDNAFGIYQKILAGKIDFPRHLEFSVKDLIRKLLVTDRTRRLGNMKNGAEDVKQHRWFRVVDWGAVPERKLKSHGCSPPGSSVHGDSPRENTGPPIIPKLCSEDDTSNFEAYPENDWTSAPPVSQKELDVFKNF", "length": 368, "header": "tr|F1N591-1|F1N591_BOVIN Isoform 1 of Protein kinase cAMP-dependent X-linked catalytic subunit OS=Bos taurus OX=9913 GN=LOC505773 PE=3 SV=5 CANONICAL=F1N591-1" }, "locus": { "chromosome": "Y", "start_pos": 1774729, "end_pos": 1721552, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000019102.8", "url": "https://www.ensembl.org/id/ENSBTAT00000019102.8" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000019102.8", "url": "https://www.ensembl.org/id/ENSBTAP00000019102.8" } ] } } ], 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"MPWTEEPGGLQSMGSQESGTRLKRLHSRTRTEPGGRSQSLRSRILSARTRTEPGGRSQSPRSRILSAQSSAVSCETQLRRRYQFDSSALTALQALKRKKRLEKQLTQIDGTLSTIEFQREALENSYTNTEVLKNMGLAAKAMKAVHENMDLNKIDDLMQEITEQQDIAQEISEAFSQRVGFGDDFDEDELMAELEELEQEELNKKMTNIRLPNAPSSSLPAQPDRGSGRMPGAPSARRSRAASSRRTEGEDDDIQHLAAWAT", "length": 262, "header": "tr|A0AAA9TV04-1|F6RDN5_BOVIN Computationally mapped isoform of Charged multivesicular body protein 4C OS=Bos taurus OX=9913 GN=CHMP4C PE=3 SV=1 CANONICAL=F6RDN5-1" }, "locus": { "chromosome": "14", "start_pos": 80846153, "end_pos": 80825425, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000109548.1", "url": "https://www.ensembl.org/id/ENSBTAT00000109548.1" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000102188.1", "url": "https://www.ensembl.org/id/ENSBTAP00000102188.1" } ] } }, { "isoform_ac": "F6RDN5-1", "url": "https://www.uniprot.org/uniprotkb/F6RDN5/entry", "sequence": { "sequence": "MPGARAGPPRPPAVPSPPGARGGPGRQEMPGRGSHLRPTACGLAGATSPGLAETRANVAHLLAGAPGAPSPEPRAPRTAGRPPSTMSKLGKFFKGGGSSKSRAAPSAQEALARLRETEEMLGKKQEYLEGRIQRELSLARKHGTQNKRAALQALKRKKRLEKQLTQIDGTLSTIEFQREALENSYTNTEVLKNMGLAAKAMKAVHENMDLNKIDDLMQEITEQQDIAQEISEAFSQRVGFGDDFDEDELMAELEELEQEELNKKMTNIRLPNAPSSSLPAQPDRGSGRMPGAPSARRSRAASSRRTEGEDDDIQHLAAWAT", "length": 321, "header": "tr|F6RDN5-1|F6RDN5_BOVIN Isoform 1 of Charged multivesicular body protein 4C OS=Bos taurus OX=9913 GN=CHMP4C PE=3 SV=1 CANONICAL=F6RDN5-1" }, "locus": { "chromosome": "14", "start_pos": 80854085, "end_pos": 80825425, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000006291.7", "url": "https://www.ensembl.org/id/ENSBTAT00000006291.7" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000006291.6", "url": "https://www.ensembl.org/id/ENSBTAP00000006291.6" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [], "orthologs": [], "go_annotation": { "categories": [ { "name": "Biological Process", "total": 17, "go_terms": [ { "name": "vacuolar transport", "id": "GO:0007034", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007034", "evidence": [ { "database": "UniProtKB", "id": "F6RDN5", "url": "https://www.uniprot.org/uniprotkb/F6RDN5" } ], "pmid": "" }, { "name": "protein transport", "id": "GO:0015031", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0015031", "evidence": [ { "database": "UniProtKB", "id": "F6RDN5", "url": "https://www.uniprot.org/uniprotkb/F6RDN5" } ], "pmid": "" }, { "name": "plasma membrane repair", "id": "GO:0001778", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0001778", "evidence": [ { "database": "UniProtKB", "id": "F6RDN5", "url": "https://www.uniprot.org/uniprotkb/F6RDN5" } ], "pmid": "" }, { "name": "regulation of centrosome duplication", "id": "GO:0010824", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0010824", "evidence": [ { "database": "UniProtKB", "id": "F6RDN5", "url": "https://www.uniprot.org/uniprotkb/F6RDN5" } ], "pmid": "" }, { "name": "nuclear membrane reassembly", "id": "GO:0031468", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0031468", "evidence": [ { "database": "UniProtKB", "id": "F6RDN5", "url": "https://www.uniprot.org/uniprotkb/F6RDN5" } ], "pmid": "" }, { "name": "viral budding via host ESCRT complex", "id": "GO:0039702", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0039702", "evidence": [ { "database": "UniProtKB", "id": "F6RDN5", "url": "https://www.uniprot.org/uniprotkb/F6RDN5" } ], "pmid": "" }, { "name": "multivesicular body sorting pathway", "id": "GO:0071985", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0071985", "evidence": [ { "database": "UniProtKB", "id": "F6RDN5", "url": "https://www.uniprot.org/uniprotkb/F6RDN5" } ], "pmid": "" }, { "name": "autophagosome maturation", "id": "GO:0097352", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0097352", "evidence": [ { "database": "UniProtKB", "id": "F6RDN5", "url": "https://www.uniprot.org/uniprotkb/F6RDN5" } ], "pmid": "" }, { "name": "mitotic metaphase chromosome alignment", "id": "GO:0007080", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007080", "evidence": [ { "database": "UniProtKB", "id": "F6RDN5", "url": "https://www.uniprot.org/uniprotkb/F6RDN5" } ], "pmid": "" }, { "name": "negative regulation of cytokinesis", "id": "GO:0032466", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0032466", "evidence": [ { "database": "UniProtKB", "id": "F6RDN5", "url": "https://www.uniprot.org/uniprotkb/F6RDN5" } ], "pmid": "" }, { "name": "mitotic cytokinesis checkpoint signaling", "id": "GO:0044878", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0044878", "evidence": [ { "database": "UniProtKB", "id": "F6RDN5", "url": "https://www.uniprot.org/uniprotkb/F6RDN5" } ], "pmid": "" }, { "name": "late endosome to lysosome transport", "id": "GO:1902774", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:1902774", "evidence": [ { "database": "UniProtKB", "id": "F6RDN5", "url": "https://www.uniprot.org/uniprotkb/F6RDN5" } ], "pmid": "" }, { "name": "regulation of mitotic spindle assembly", "id": "GO:1901673", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:1901673", "evidence": [ { "database": "UniProtKB", "id": "F6RDN5", "url": "https://www.uniprot.org/uniprotkb/F6RDN5" } ], "pmid": "" }, { "name": "ubiquitin-independent protein catabolic process via the multivesicular body sorting pathway", "id": "GO:0090611", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0090611", "evidence": [ { "database": "UniProtKB", "id": "F6RDN5", "url": "https://www.uniprot.org/uniprotkb/F6RDN5" } ], "pmid": "" }, { "name": "ubiquitin-dependent protein catabolic process via the multivesicular body sorting pathway", "id": "GO:0043162", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0043162", "evidence": [ { "database": "UniProtKB", "id": "F6RDN5", "url": "https://www.uniprot.org/uniprotkb/F6RDN5" } ], "pmid": "" }, { "name": "viral budding from plasma membrane", "id": "GO:0046761", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0046761", "evidence": [ { "database": "UniProtKB", "id": "F6RDN5", "url": "https://www.uniprot.org/uniprotkb/F6RDN5" } ], "pmid": "" }, { "name": "midbody abscission", "id": "GO:0061952", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0061952", "evidence": [ { "database": "UniProtKB", "id": "F6RDN5", "url": "https://www.uniprot.org/uniprotkb/F6RDN5" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 9, "go_terms": [ { "name": "cytosol", "id": "GO:0005829", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005829", "evidence": [ { "database": "UniProtKB", "id": "F6RDN5", "url": "https://www.uniprot.org/uniprotkb/F6RDN5" } ], "pmid": "" }, { "name": "late endosome membrane", "id": "GO:0031902", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0031902", "evidence": [ { "database": "UniProtKB", "id": "F6RDN5", "url": "https://www.uniprot.org/uniprotkb/F6RDN5" } ], "pmid": "" }, { "name": "kinetochore microtubule", "id": 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"bta:514601", "url": "https://www.genome.jp/dbget-bin/www_bget?bta:514601", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "NRYPVKQ", "url": "https://omabrowser.org/oma/group/NRYPVKQ/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "F1N4Z9", "url": "https://www.orthodb.org/?gene=F1N4Z9", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR21456", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR21456", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR21456:SF3", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR21456:SF3", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF10358", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF10358", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "XP_002686207", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_002686207", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0AAA9TFP0", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TFP0", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0AAA9TFP0-1", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TFP0-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "F1N4Z9", "url": "https://www.uniprot.org/uniprotkb/F1N4Z9", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "F1N4Z9-1", "url": "https://www.uniprot.org/uniprotkb/F1N4Z9-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MMMKKKKFKFKVDFELEELSSVPFVNGVLFCKMRLLDGGSFTAESPREVVQANCVHWRKKFSFMCKMSASATTGVLDPCIYRVSVRKELKGGKAYAKLGFADLNLAEFAGSGNTTRRCLLEGYDTKNTRQDNSILKVWISMQLMSGDPCFKTPPSTSMCIPIAGESESLEEDRKGGETLKIHLGIADLSAKSASVPDELGACGHSRTSSYASQQSKVSGYSSCHSRSSSLSELCHRRNTSVGSTSTGIESILEPCDEVEQKTAEPSLDVADKEDTALEILNRCPVKQDSVESQLKRVDDTRVDADDIVEKILQSQDFSLDSSAEEEGLRLFVGPGGRTTFGSRHLPNRVGSGAYEQVVIKR", "length": 361, "header": "tr|F1N4Z9-1|F1N4Z9_BOVIN Isoform 1 of EEIG family member 2 OS=Bos taurus OX=9913 GN=EEIG2 PE=3 SV=3 CANONICAL=F1N4Z9-1" }, "isoforms": [ { "isoform_ac": "A0AAA9TFP0-1", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TFP0/entry", "sequence": { "sequence": "MMMKKKKFKFKVDFELEELSSVPFVNGVLFCKMRLLDGGSFTAESPREVVQANCVHWRKKFSFMCKMSASATTGVLDPCIYRVSVRKLGFADLNLAEFAGSGNTTRRCLLEGYDTKNTRQDNSILKVWISMQLMSGDPCFKTPPSTSMCIPIAGESESLEEDRKGGETLKIHLGIADLSAKSASVPDELGACGHSRTSSYASQQSKVSGYSSCHSRSSSLSELCHRRNTSVGSTSTGIESILEPCDEVEQKTAEPSLDVADKEDTALEILNRCPVKQDSVESQLKRVDDTRVDADDIVEKILQSQDFSLDSSAEEEGLRLFVGPGGRTTFGSRHLPNRVGSGAYEQVVIKR", "length": 351, "header": "tr|A0AAA9TFP0-1|F1N4Z9_BOVIN Computationally mapped isoform of EEIG family member 2 OS=Bos taurus OX=9913 GN=EEIG2 PE=3 SV=1 CANONICAL=F1N4Z9-1" }, "locus": { "chromosome": "3", "start_pos": 34804673, "end_pos": 34726396, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000123070.1", "url": "https://www.ensembl.org/id/ENSBTAT00000123070.1" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000095672.1", "url": "https://www.ensembl.org/id/ENSBTAP00000095672.1" } ] } }, { "isoform_ac": "F1N4Z9-1", "url": "https://www.uniprot.org/uniprotkb/F1N4Z9/entry", "sequence": { "sequence": "MMMKKKKFKFKVDFELEELSSVPFVNGVLFCKMRLLDGGSFTAESPREVVQANCVHWRKKFSFMCKMSASATTGVLDPCIYRVSVRKELKGGKAYAKLGFADLNLAEFAGSGNTTRRCLLEGYDTKNTRQDNSILKVWISMQLMSGDPCFKTPPSTSMCIPIAGESESLEEDRKGGETLKIHLGIADLSAKSASVPDELGACGHSRTSSYASQQSKVSGYSSCHSRSSSLSELCHRRNTSVGSTSTGIESILEPCDEVEQKTAEPSLDVADKEDTALEILNRCPVKQDSVESQLKRVDDTRVDADDIVEKILQSQDFSLDSSAEEEGLRLFVGPGGRTTFGSRHLPNRVGSGAYEQVVIKR", "length": 361, "header": "tr|F1N4Z9-1|F1N4Z9_BOVIN Isoform 1 of EEIG family member 2 OS=Bos taurus OX=9913 GN=EEIG2 PE=3 SV=3 CANONICAL=F1N4Z9-1" }, "locus": { "chromosome": "3", "start_pos": 34804673, "end_pos": 34726396, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000007157.7", "url": "https://www.ensembl.org/id/ENSBTAT00000007157.7" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000007157.6", "url": "https://www.ensembl.org/id/ENSBTAP00000007157.6" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [ { "id": "bta:514601", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?bta:514601", "resource": "KEGG Pathway" } ], "orthologs": [ { "uniprot_canonical_ac": "A0A0G2JVH9-1", "protein_name": "EEIG family member 2", "gene_name": "Eeig2", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MMKKKKFKFKVDFELEELSSVPFVNGVLFCKMRLLDGGTFTAESSREVVQANCVHWRKKFSFMCKMSASASTGILDPCIYRVSVRKELKGGKAYAKLGFADLNLAEFAGSGSTTRRCLLEGYDTKNTRQDNSILKVLISMQLMSGDPCFKTPPSTSMSIPIAGESESLEEDRKGGETLKVHLGIADLSAKSASVPDELGAWGHSRTSSYASQQSKVSGYSTCHSRSSSFSEFCHRRNTSVGSTSTGIESILEPCDETEQITTEPNPDPVSAAAAVKEEEAPEKLPRCPVKQDSVESQLKRVDDTRVDADDVVEKILQSQDFSLDSSAEEEGLRLFVGPGGSTTFGSHHLPNRVGSGAYEQVVIKR", "length": 365 }, "evidence": [ { "id": "F1N4Z9", "url": "https://omabrowser.org/oma/group/F1N4Z9/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "A0A287A4N0-1", "protein_name": "EEIG family member 2", "gene_name": "EEIG2", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MMKKKKFKFKVDFGLEELSSVPFVNGVLFCKMRLLDGGSFTAESPREVVQANCVHWKKKFSFMCKMSASAATGILDPCIYRVSVRKELKGGKAYAKLGFADLNLAEFAGSGNTTRRCLLEGYDTKNTRQDNSILKVLISMQLMSGDPCFKTPPSTSMSIPIAGESESLEEDRKGGETLKIHLGIADLSAKSASVPDELGACGHSRTSSYASQQSKVSGYSSCHSRSSSFSELCHRRNTSVGSTSTGIESILEPCDELEQKIAEPNLDPADKEDTASETLNRCPVKQDSVESQLKRVDDTRVDADDIVEKILQSQDFSLDSSAEEEGLRLFVGPGGSTTFGSRHLPNRVGSGAYEQVVIKR", "length": 360 }, "evidence": [ { "id": "F1N4Z9", "url": "https://omabrowser.org/oma/group/F1N4Z9/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "Q5T8I3-1", "protein_name": "EEIG family member 2", "gene_name": "EEIG2", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MMKKKKFKFKVDFELEELSSVPFVNGVLFCKMRLLDGGSFTAESSREVVQANCVRWRKKFSFMCKMSASAATGILDPCIYRVSVRKELKGGKAYAKLGFADLNLAEFAGSGNTTRRCLLEGYDTKNTRQDNSILKVLISMQLMSGDPCFKTPPSTSMSIPIAGESESLQEDRKGGETLKVHLGIADLSAKSASVPDELGACGHSRTSSYASQQSKVSGYSTCHSRSSSFSELCHRRNTSVGSTSTGVESILEPCDEIEQKIAEPNLDTADKEDTASEKLSRCPVKQDSVESQLKRVDDTRVDADDIVEKILQSQDFSLDSSAEEEGLRLFVGPGGSTTFGSHHLPNRVGSGAYEQVVIKR", "length": 360 }, "evidence": [ { "id": "F1N4Z9", "url": "https://omabrowser.org/oma/group/F1N4Z9/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "Q8BQS4-1", "protein_name": "EEIG family member 2", "gene_name": "Eeig2", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MRLLDGGSFTAESSREVVQANCVHWRKKFSFMCKMSASASTGILDPCIYRVSVRKELKGGKAYAKLGFADLNLAEFAGSGNTTRRCLLEGYDTKNTRQDNSILKVLISMQLMSGDPCFKTPPSTSMSIPIAGESESLEEDRKGGETLKVHLGIADLSAKSASVPDELGAWGHSRTSSYASQQSKVSGYSTCHSRSSSFSEFCHRRNTSVGSTSTGIESILEPCDETEPITAEPSPDPTAAAATATTTTAKEEEASEKLARCPVKQDSVESQLKRVDDTRVDADDIVEKILQSQDFSLDSSAEEEGLRLFVGPGGSTTFGSHHLPNRVGSGAYEQVVIKR", "length": 339 }, "evidence": [ { "id": "F1N4Z9", "url": "https://omabrowser.org/oma/group/F1N4Z9/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" } ], "go_annotation": {}, "pro_annotation": [], "site_annotation": [ { "start_pos": 113, "end_pos": 115, "annotation": "n_glycosylation_sequon" }, { "start_pos": 238, "end_pos": 240, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [ { "pdb_id": "AF-F1N4Z9-F1", "pdb_chain": "global", "start_pos": 1, "end_pos": 361, "overlap": "1.0", "method": "AlphaFold", "type": "alphafold", "resolution": -1.0, "url": "https://data.glygen.org/ln2downloads/pdb/current/AF-F1N4Z9-F1.pdb", "url_external": "https://alphafold.ebi.ac.uk/entry/F1N4Z9" } ], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "F1N4Z9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1N4Z9" }, { "id": "PS51840", "database": "PROSITE", "url": "https://prosite.expasy.org/PS51840" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "C2 NT-type", "eco_id": "ECO_0000259", "start_pos": 1, "end_pos": 143, "start_aa": "Met", "end_aa": "Leu", "glycosite_overlap": [] } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" }, { "name": "homologset.oma", "label": "OMA Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 113, "end_pos": 115 }, { "start_pos": 238, "end_pos": 240 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ], "tool_support": { "graph_view": "yes" } }, { "uniprot_canonical_ac": "F1N680-1", "uniprot_ac": "F1N680", "uniprot_id": "F1N680_BOVIN", "mass": { "chemical_mass": 20210.0, "monoisotopic_mass": 20210.0 }, "refseq": {}, "gene_names": [ { "name": "CMTM6", "type": "recommended", "evidence": [ { "id": "F1N680", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1N680" } ] } ], "protein_names": [ { "name": "CKLF like MARVEL transmembrane domain containing 6", "type": "synonym", "evidence": [ { "id": "F1N680", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1N680/entry#names_and_taxonomy" } ] } ], "function": [], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Bos taurus", "taxid": 9913, "evidence": [ { "database": "UniProtKB", "id": "F1N680", "url": "https://www.uniprot.org/uniprotkb/F1N680" } ], "common_name": "Bovine", "glygen_name": "Bovine", "reference_species": "Bos taurus [9913]" } ], "gene": [ { "name": "CMTM6", "url": "https://www.uniprot.org/uniprotkb/F1N680", "locus": { "chromosome": "22", "start_pos": 6929371, "end_pos": 6951459, "strand": "+", "evidence": [ { "database": "Ensembl Gene", "id": "ENSBTAG00000019526", "url": "https://www.ensembl.org/id/ENSBTAG00000019526" } ] } } ], "crossref": [ { "id": "F1N680", "url": "https://alphafold.ebi.ac.uk/entry/F1N680", "database": "AlphaFoldDB", "categories": [] }, { "id": "ENSBTAG00000019526", "url": "https://bgee.org/?page=gene&gene_id=ENSBTAG00000019526", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "IPR008253", "url": "https://www.ebi.ac.uk/interpro/entry/IPR008253", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR050578", "url": "https://www.ebi.ac.uk/interpro/entry/IPR050578", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "ASMVWEK", "url": "https://omabrowser.org/oma/group/ASMVWEK/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "F1N680", "url": "https://www.orthodb.org/?gene=F1N680", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR22776", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR22776", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR22776:SF25", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR22776:SF25", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF01284", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF01284", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "R-BTA-6798695", "url": "https://www.reactome.org/PathwayBrowser/#R-BTA-6798695", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "A0AAA9TGQ9", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TGQ9", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0AAA9TGQ9-1", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TGQ9-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "F1N680", "url": "https://www.uniprot.org/uniprotkb/F1N680", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "F1N680-1", "url": "https://www.uniprot.org/uniprotkb/F1N680-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MENGQVYRATTEAHSGPGIGPRSGLAAYFTLSRLTGFRRLKLLELVLSLLAFICEEVVSQCTLCGGLYFFEFVSCSAFLLSLLILVVYCTPVYDRVDPAKVKSSDFFITLGTGLVFFVASLTFTLTHDNTIAEIAAIVFGMLASLTYLAEFSFMLREKLKEPRPRKGEATMRREHLTEPLNA", "length": 182, "header": "tr|F1N680-1|F1N680_BOVIN Isoform 1 of CKLF like MARVEL transmembrane domain containing 6 OS=Bos taurus OX=9913 GN=CMTM6 PE=4 SV=2 CANONICAL=F1N680-1" }, "isoforms": [ { "isoform_ac": "A0AAA9TGQ9-1", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TGQ9/entry", "sequence": { "sequence": "MENGQVYRATTEAHSGPGIGPRSGLAAYFTLSRLTGFRRLKLLELVLSLLAFICEEVVSQCTLCGGLYFFEFVSCSAFLLSLLILVVYCTPVYDRVDPAKVKSSDFFITLGTGLVFFVASLTFTLTHDNTIAEIAAILSEFQNCRSRIVDLIGARRRQWQATPVLLPGESQGQGSLVGCCLWGRTESDTTEAV", "length": 193, "header": "tr|A0AAA9TGQ9-1|F1N680_BOVIN Computationally mapped isoform of CKLF like MARVEL transmembrane domain containing 6 OS=Bos taurus OX=9913 GN=CMTM6 PE=4 SV=1 CANONICAL=F1N680-1" }, "locus": { "chromosome": "22", "start_pos": 6951407, "end_pos": 6933624, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000131100.1", "url": "https://www.ensembl.org/id/ENSBTAT00000131100.1" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000097372.1", "url": "https://www.ensembl.org/id/ENSBTAP00000097372.1" } ] } }, { "isoform_ac": "F1N680-1", "url": "https://www.uniprot.org/uniprotkb/F1N680/entry", "sequence": { "sequence": "MENGQVYRATTEAHSGPGIGPRSGLAAYFTLSRLTGFRRLKLLELVLSLLAFICEEVVSQCTLCGGLYFFEFVSCSAFLLSLLILVVYCTPVYDRVDPAKVKSSDFFITLGTGLVFFVASLTFTLTHDNTIAEIAAIVFGMLASLTYLAEFSFMLREKLKEPRPRKGEATMRREHLTEPLNA", "length": 182, "header": "tr|F1N680-1|F1N680_BOVIN Isoform 1 of CKLF like MARVEL transmembrane domain containing 6 OS=Bos taurus OX=9913 GN=CMTM6 PE=4 SV=2 CANONICAL=F1N680-1" }, "locus": { "chromosome": "22", "start_pos": 6951407, "end_pos": 6931643, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000026019.5", "url": "https://www.ensembl.org/id/ENSBTAT00000026019.5" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000026019.4", "url": "https://www.ensembl.org/id/ENSBTAP00000026019.4" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [ { "id": "R-BTA-6798695", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-BTA-6798695", "resource": "Reactome", "description": "Neutrophil degranulation" } ], "orthologs": [ { "uniprot_canonical_ac": "A0A8V0X586-1", "protein_name": "CKLF like MARVEL transmembrane domain containing 6", "gene_name": "CMTM6", "tax_id": 9031, "organism": "Gallus gallus", "sequence": { "sequence": "SLLFSRLNSPSSLSLSSQGRCSITWIIFFFFFFGPPLDALQQVHVFPILRTPHLDAVRQVLSFLAVIFEEIVEDCINCHGLYFFEFVSCSAFLLSLLTLCVYCTIAYETFGKDKVNKVNFWTMLIIGAFFLIASIVLAATSSGSAFEKAACVFGFFASGAFLAEFIWDLWCSRKQSTEERSENPGHTQGATEDQPLNKPS", "length": 200 }, "evidence": [ { "id": "F1N680", "url": "https://omabrowser.org/oma/group/F1N680/", "database": "OMA" } ], "glygen_name": "Chicken", "common_name": "Chicken" }, { "uniprot_canonical_ac": "Q7TNZ9-1", "protein_name": "CKLF-like MARVEL transmembrane domain containing 6", "gene_name": "Cmtm6", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "PKNGAVYSPTTEAAPGAGRGARSGLAAYFFLGRLPWYRRILKGLQLLLSLLAFICEEVVSECGLCGGLYFFEFVSCSAFLLSLLLLIVYCTAVYDRVDTGKVKSSDFYITLGTGCVFLLASIIFVSTHSGTSAEIAAIVFGFLGSSMFLLDFVVMLCEKLRESPLRKPENNARAEALTEPLNA", "length": 183 }, "evidence": [ { "id": "F1N680", "url": "https://omabrowser.org/oma/group/F1N680/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "Q9CZ69-1", "protein_name": "CKLF-like MARVEL transmembrane domain-containing protein 6", "gene_name": "Cmtm6", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MENGAVYSPTTEAAPGTGRGARSGLAAYFVLGRLPWHRRILKGLQLLLSLLAFICEEVVSECGLCGGLYFFEFVSCSAFLLSLLLLIVYCTPVHDRVDTGKVKSSDFYITLGTGCVFLLASIIFVSTHSGTSAEIAAIVFGFLASSMFLLDFVVMLCEKLRESPLRKPENNAKVEALTEPLNA", "length": 183 }, "evidence": [ { "id": "F1N680", "url": "https://omabrowser.org/oma/group/F1N680/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" } ], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 4, "go_terms": [ { "name": "plasma membrane", "id": "GO:0005886", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005886", "evidence": [ { "database": "UniProtKB", "id": "F1N680", "url": "https://www.uniprot.org/uniprotkb/F1N680" } ], "pmid": "" }, { "name": "early endosome membrane", "id": "GO:0031901", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0031901", "evidence": [ { "database": "UniProtKB", "id": "F1N680", "url": "https://www.uniprot.org/uniprotkb/F1N680" } ], "pmid": "" }, { "name": "recycling endosome membrane", "id": "GO:0055038", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0055038", "evidence": [ { "database": "UniProtKB", "id": "F1N680", "url": "https://www.uniprot.org/uniprotkb/F1N680" } ], "pmid": "" }, { "name": "membrane", "id": "GO:0016020", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016020", "evidence": [ { "database": "UniProtKB", "id": "F1N680", "url": "https://www.uniprot.org/uniprotkb/F1N680" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 3, "go_terms": [ { "name": "protein transport", "id": "GO:0015031", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0015031", "evidence": [ { "database": "UniProtKB", "id": "F1N680", "url": "https://www.uniprot.org/uniprotkb/F1N680" } ], "pmid": "" }, { "name": "regulation of protein stability", "id": "GO:0031647", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0031647", "evidence": [ { "database": "UniProtKB", "id": "F1N680", "url": "https://www.uniprot.org/uniprotkb/F1N680" } ], "pmid": "" }, { "name": "endocytic recycling", "id": "GO:0032456", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0032456", "evidence": [ { "database": "UniProtKB", "id": "F1N680", "url": "https://www.uniprot.org/uniprotkb/F1N680" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [ { "pdb_id": "AF-F1N680-F1", "pdb_chain": "global", "start_pos": 1, "end_pos": 182, "overlap": "1.0", "method": "AlphaFold", "type": "alphafold", "resolution": -1.0, "url": "https://data.glygen.org/ln2downloads/pdb/current/AF-F1N680-F1.pdb", "url_external": "https://alphafold.ebi.ac.uk/entry/F1N680" } ], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "F1N680", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1N680" }, { "id": "PS51225", "database": "PROSITE", "url": "https://prosite.expasy.org/PS51225" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "MARVEL", "eco_id": "ECO_0000259", "start_pos": 32, "end_pos": 159, "start_aa": "Ser", "end_aa": "Leu", "glycosite_overlap": [] } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" }, { "name": "homologset.oma", "label": "OMA Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": 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"uniprot_canonical_ac": "F6PTU3-1", "uniprot_ac": "F6PTU3", "uniprot_id": "F6PTU3_BOVIN", "mass": { "chemical_mass": 91485.0, "monoisotopic_mass": 91485.0 }, "refseq": {}, "gene_names": [ { "name": "SUN2", "type": "recommended", "evidence": [ { "id": "F6PTU3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F6PTU3" } ] } ], "protein_names": [ { "name": "Sad1 and UNC84 domain containing 2", "type": "synonym", "evidence": [ { "id": "F6PTU3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F6PTU3/entry#names_and_taxonomy" } ] } ], "function": [], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Bos taurus", "taxid": 9913, "evidence": [ { "database": "UniProtKB", "id": "F6PTU3", "url": "https://www.uniprot.org/uniprotkb/F6PTU3" } ], "common_name": "Bovine", "glygen_name": "Bovine", "reference_species": "Bos taurus [9913]" } ], "gene": [ { "name": "SUN2", "url": "https://www.uniprot.org/uniprotkb/F6PTU3", "locus": { "chromosome": "5", "start_pos": 110358967, "end_pos": 110377522, "strand": "+", "evidence": [ { "database": "Ensembl Gene", "id": "ENSBTAG00000003693", "url": "https://www.ensembl.org/id/ENSBTAG00000003693" } ] } } ], "crossref": [ { "id": "F6PTU3", "url": "https://alphafold.ebi.ac.uk/entry/F6PTU3", "database": "AlphaFoldDB", "categories": [] }, { "id": "cd21438", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd21438", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "IPR012919", "url": "https://www.ebi.ac.uk/interpro/entry/IPR012919", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR040994", "url": "https://www.ebi.ac.uk/interpro/entry/IPR040994", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR045119", "url": "https://www.ebi.ac.uk/interpro/entry/IPR045119", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "PTHR12911", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR12911", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR12911:SF22", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR12911:SF22", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF07738", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF07738", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF18580", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF18580", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "A0AAA9TIA9", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TIA9", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0AAA9TIA9-1", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TIA9-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "F6PTU3", "url": "https://www.uniprot.org/uniprotkb/F6PTU3", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "F6PTU3-1", "url": "https://www.uniprot.org/uniprotkb/F6PTU3-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MGCGLSALTDRRTHTHSATRAPSGPTRAAQFSAGRIVRLPALLPLLPERPGSPCRPPLPGLRRGKGGRRGGPRKPLALYGAAAEADSLQGKGPPAHLIMSRRSQRLTRYSSQGEDDGGSSSSGGSSVMGSQSTLFKDSPLRTLKKKTNNSKRLSPAPQLGPSSDTHTYYSESVVRESYIGSPRAASIAASLTRHSLLDDPYWSEDLRVRRRRGTGGTDSSKPNGLPENKLSEDFLGSSSGYSSEDDYVGYSETDHQGSGSRLRNAVSRVGSLLWMVVTSPGRLFGLLYWWIGTTWYRLTTAASLLDVFVLTRRFSSLKMFLWFLLLLLLLTGLTYGAWYFYPFGLQTLHPAVVSWWASKGSIGQREVWESRDSSPHFQAEQRILSRVHSLERRLDALAAEFSSSWQKEAMRLERLELQQGAGGQGGGGGGLSHEDTLALLEGLVSRREAALKEDLRRDTAARIQEELVTLRSEHQQDSEDLFKKIVQASQESEARLQQLKSEWQRMTQESFQENAMKELGRLEGQLAGLRQELAALTLKQSLVEDQVGLLPQQLQAVRDDVESQFPAWVSQFLLRGGGTRTGLLQQEEMEAQLRDLESRILTHVAEMQGKSAREAVASLGLTLQREGVIGVTEEQVHRIVNQALKRYSEDRIGMVDYALESGGASVISTRCSETYETKTALLSLFGIPLWYHSQSPRVILQPDVHPGNCWAFQGPQGFAVVRLSARIRPTAVTLEHVPKSLSPNSTISSAPKDFAIFGLDEDLQQEGTPLGQFTYDQDGEPIQTFYFQDPKMATYQVVELRILTNWGHPEYTCIYRFRVHGEPAH", "length": 825, "header": "tr|F6PTU3-1|F6PTU3_BOVIN Isoform 1 of Sad1 and UNC84 domain containing 2 OS=Bos taurus OX=9913 GN=SUN2 PE=4 SV=1 CANONICAL=F6PTU3-1" }, "isoforms": [ { "isoform_ac": "A0AAA9TIA9-1", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TIA9/entry", "sequence": { "sequence": "MGCGLSALTDRRTHTHSATRAPSGPTRAAQFSAGRIVRLPALLPLLPERPGSPCRPPLPGLRRGKGGRRGGPRKPLALYGAAAEADSLQGKGPPAHLIMSRRSQRLTRYSSQGEDDGGSSSSGGSSVMGSQSTLFKDSPLRTLKKKTNNSKRLSPAPQLGPSSDTHTYYSESVVRESYIGSPRAASIAASLTRHSLLDDPYWSEDLRVRRRRGTGGTDSSKPNGLPENKLSEDFLGSSSGYSSEDDYVGYSETDHQGSGSRLRNAVSRVGSLLWMVVTSPGRLFGLLYWWIGTTWYRLTTAASLLDVFVLTRRFSSLKMFLWFLLLLLLLTGLTYGAWYFYPFGLQTLHPAVVSWWASKGSIGQREVWESRDSSPHFQAEQRILSRVHSLERRLDALAAEFSSSWQKEAMRLERLELQQGAGGQGGGGGGLSHEDTLALLEGLVSRREAALKEDLRRDTAARIQEELVTLRSEHQQDSEDLFKKIVQASQESEARLQQLKSEWQRMTQESFQENAMKELGRLEGQLAGLRQELAALTLKQSLVEDQVGLLPQQLQAVRDDVESQFPAWVSQFLLRGGGTRTGLLQQEEMEAQLRDLESRILTHVAEMQGKSAREAVASLGLTLQREGVIGVTEEQVHRIVNQALKRYSEDRIGMVDYALESGGASVISTRCSETYETKTALLSLFGIPLWYHSQSPRVILQPDVHPGNCWAFQGPQGFAVVRLSARIRPTAVTLEHVPKSLSPNSTISSAPKDFAIFGLDEDLQQEGTPLGQFTYDQDGEPIQTFYFQDLRRLWGFLVHPLETLFQGLKTGFLKSGFSAEA", "length": 821, "header": "tr|A0AAA9TIA9-1|F6PTU3_BOVIN Computationally mapped isoform of Sad1 and UNC84 domain containing 2 OS=Bos taurus OX=9913 GN=SUN2 PE=4 SV=1 CANONICAL=F6PTU3-1" }, "locus": { "chromosome": "5", "start_pos": 110377323, "end_pos": 110360663, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000125801.1", "url": "https://www.ensembl.org/id/ENSBTAT00000125801.1" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000098033.1", "url": "https://www.ensembl.org/id/ENSBTAP00000098033.1" } ] } }, { "isoform_ac": "F6PTU3-1", "url": "https://www.uniprot.org/uniprotkb/F6PTU3/entry", "sequence": { "sequence": "MGCGLSALTDRRTHTHSATRAPSGPTRAAQFSAGRIVRLPALLPLLPERPGSPCRPPLPGLRRGKGGRRGGPRKPLALYGAAAEADSLQGKGPPAHLIMSRRSQRLTRYSSQGEDDGGSSSSGGSSVMGSQSTLFKDSPLRTLKKKTNNSKRLSPAPQLGPSSDTHTYYSESVVRESYIGSPRAASIAASLTRHSLLDDPYWSEDLRVRRRRGTGGTDSSKPNGLPENKLSEDFLGSSSGYSSEDDYVGYSETDHQGSGSRLRNAVSRVGSLLWMVVTSPGRLFGLLYWWIGTTWYRLTTAASLLDVFVLTRRFSSLKMFLWFLLLLLLLTGLTYGAWYFYPFGLQTLHPAVVSWWASKGSIGQREVWESRDSSPHFQAEQRILSRVHSLERRLDALAAEFSSSWQKEAMRLERLELQQGAGGQGGGGGGLSHEDTLALLEGLVSRREAALKEDLRRDTAARIQEELVTLRSEHQQDSEDLFKKIVQASQESEARLQQLKSEWQRMTQESFQENAMKELGRLEGQLAGLRQELAALTLKQSLVEDQVGLLPQQLQAVRDDVESQFPAWVSQFLLRGGGTRTGLLQQEEMEAQLRDLESRILTHVAEMQGKSAREAVASLGLTLQREGVIGVTEEQVHRIVNQALKRYSEDRIGMVDYALESGGASVISTRCSETYETKTALLSLFGIPLWYHSQSPRVILQPDVHPGNCWAFQGPQGFAVVRLSARIRPTAVTLEHVPKSLSPNSTISSAPKDFAIFGLDEDLQQEGTPLGQFTYDQDGEPIQTFYFQDPKMATYQVVELRILTNWGHPEYTCIYRFRVHGEPAH", "length": 825, "header": "tr|F6PTU3-1|F6PTU3_BOVIN Isoform 1 of Sad1 and UNC84 domain containing 2 OS=Bos taurus OX=9913 GN=SUN2 PE=4 SV=1 CANONICAL=F6PTU3-1" }, "locus": { "chromosome": "5", "start_pos": 110377323, "end_pos": 110360470, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000004813.7", "url": "https://www.ensembl.org/id/ENSBTAT00000004813.7" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000004813.6", "url": "https://www.ensembl.org/id/ENSBTAP00000004813.6" } ] } } ], "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "other", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 26, "start_aa": "Thr", "end_pos": 26, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr26", "evidence": [ { "id": "", "database": "GlyGen", "url": "https://data.glygen.org/" } ], "filter_code": "000000000000000010000.00000000001000.0.01000" } ], "phosphorylation": [], "glycation": [], "keywords": [ 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"MQRSAVTSSGERPGRGGWFPPPPAAALLPERLLRPLSTPPPPLPPTSPPPPPSPFRAPPPPLHDLGPLFLRGSLTRARWRARRVAMADGGGGGSTGAVGGGGAGPASAGAAAGGGGAGGSGGPINPASLPPGDPQLIALIVEQLKSRGLFDSFRRDCLADVDTKPAYQNLRQKVDNFVSTHLDKQEWNPTMNKNQLRNGLRQSVVQSGMLEAGVDRIISQVVDPKLNHIFRPQIERAIHEFLAAQKKEAVPAPPPEPESQDPAAPSQDAS", "length": 270, "header": "tr|F1N2T2-1|F1N2T2_BOVIN Isoform 1 of Biorientation of chromosomes in cell division 1 OS=Bos taurus OX=9913 GN=BOD1 PE=3 SV=2 CANONICAL=F1N2T2-1" }, "isoforms": [ { "isoform_ac": "A0AAA9TLS5-1", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TLS5/entry", "sequence": { "sequence": "MADGGGGGSTGAVGGGGAGPASAGAAAGGGGAGGSGGPINPASLPPGDPQLIALIVEQLKSRGLFDSFRRDCLADVDTKPAYQNLRQKVDNFVSTHLDKQEWNPTMNKNQLRNGLRQSVVQICLTCFGSSVE", "length": 132, "header": "tr|A0AAA9TLS5-1|F1N2T2_BOVIN Computationally mapped isoform of Biorientation of chromosomes in cell division 1 OS=Bos taurus OX=9913 GN=BOD1 PE=3 SV=1 CANONICAL=F1N2T2-1" }, "locus": { "chromosome": "20", "start_pos": 5331602, "end_pos": 5320257, "strand": 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"length": 379, "header": "tr|F6QTR5-1|F6QTR5_BOVIN Isoform 1 of Coenzyme Q10A OS=Bos taurus OX=9913 GN=COQ10A PE=3 SV=1 CANONICAL=F6QTR5-1" }, "locus": { "chromosome": "5", "start_pos": 57069346, "end_pos": 57066367, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000005722.4", "url": "https://www.ensembl.org/id/ENSBTAT00000005722.4" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000005722.3", "url": "https://www.ensembl.org/id/ENSBTAP00000005722.3" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [], "orthologs": [], "go_annotation": { "categories": [ { "name": "Biological Process", "total": 1, "go_terms": [ { "name": "cellular respiration", "id": "GO:0045333", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0045333", "evidence": [ { "database": "UniProtKB", "id": "F6QTR5", "url": "https://www.uniprot.org/uniprotkb/F6QTR5" } ], "pmid": "" } ] }, { "name": "Molecular Function", "total": 1, "go_terms": [ { "name": "ubiquinone binding", "id": "GO:0048039", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0048039", "evidence": [ { "database": "UniProtKB", "id": "F6QTR5", "url": "https://www.uniprot.org/uniprotkb/F6QTR5" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 1, "go_terms": [ { "name": "mitochondrial inner membrane", "id": "GO:0005743", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005743", "evidence": [ { "database": "UniProtKB", "id": "F6QTR5", "url": "https://www.uniprot.org/uniprotkb/F6QTR5" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "F6QTR5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F6QTR5" }, { "id": "PF03364", "database": "Pfam", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF03364" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "Coenzyme Q-binding protein COQ10 START", "eco_id": "ECO_0000259", "start_pos": 225, "end_pos": 354, "start_aa": "Met", "end_aa": "Glu", "glycosite_overlap": [] } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ], "tool_support": { "graph_view": "yes" } }, { "uniprot_canonical_ac": "F1N5Q1-1", "uniprot_ac": "F1N5Q1", "uniprot_id": "F1N5Q1_BOVIN", "mass": { "chemical_mass": 44921.0, "monoisotopic_mass": 44921.0 }, "refseq": {}, "gene_names": [ { "name": "ZNF691", "type": "recommended", "evidence": [ { "id": "F1N5Q1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1N5Q1" } ] } ], "protein_names": [ { "name": "Zinc finger protein 691", "type": "recommended", "evidence": [ { "id": "F1N5Q1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1N5Q1/entry#names_and_taxonomy" } ] } ], "function": [ { "annotation": "May be involved in transcriptional regulation.", "evidence": [ { "database": "UniProtKB", "id": "F1N5Q1", "url": "https://www.uniprot.org/uniprotkb/F1N5Q1#function" }, { "database": "UniProtKB", "id": "ARBA00003767", "url": "https://www.uniprot.org/uniprotkb/ARBA00003767#function" }, { "database": "UniProtKB", "id": "A0AAA9TND3", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TND3#function" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Bos taurus", "taxid": 9913, "evidence": [ { "database": "UniProtKB", "id": "F1N5Q1", "url": "https://www.uniprot.org/uniprotkb/F1N5Q1" } ], "common_name": "Bovine", "glygen_name": "Bovine", "reference_species": "Bos taurus [9913]" } ], "gene": [ { "name": "ZNF691", "url": "https://www.uniprot.org/uniprotkb/F1N5Q1", "locus": { "chromosome": "3", "start_pos": 103388587, "end_pos": 103394764, "strand": "+", "evidence": [ { "database": "Ensembl Gene", "id": "ENSBTAG00000016028", "url": "https://www.ensembl.org/id/ENSBTAG00000016028" } ] } } ], "crossref": [ { "id": "F1N5Q1", "url": "https://alphafold.ebi.ac.uk/entry/F1N5Q1", "database": "AlphaFoldDB", "categories": [] }, { "id": "ENSBTAG00000016028", "url": "https://bgee.org/?page=gene&gene_id=ENSBTAG00000016028", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "532460", "url": "https://www.ncbi.nlm.nih.gov/gene/532460", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR013087", "url": "https://www.ebi.ac.uk/interpro/entry/IPR013087", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR036236", "url": "https://www.ebi.ac.uk/interpro/entry/IPR036236", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "KTHMGEQ", "url": "https://omabrowser.org/oma/group/KTHMGEQ/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "F1N5Q1", "url": "https://www.orthodb.org/?gene=F1N5Q1", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR23235", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR23235", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR23235:SF142", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR23235:SF142", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR23235:SF152", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR23235:SF152", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00096", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00096", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF13465", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF13465", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "A0AAA9TND3", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TND3", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0AAA9TND3-1", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TND3-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "F1N5Q1", "url": "https://www.uniprot.org/uniprotkb/F1N5Q1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "F1N5Q1-1", "url": "https://www.uniprot.org/uniprotkb/F1N5Q1-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MVGSPSVSVPVLLIHPASPDSKTTFSMKLLIPELFREICLCHQNSHGTVFITGVALKSTGFGAMGMAPSSATHLVCALGRITSFLLRLELNLLHLHDSFWSWWPMTLHCTIKSFRGSEMGSEKEQSPEQHLPEEGERGNKPWRVDDSKVPDGEKEPGQANPSEAPQGPSPEEPTQEVAVSAAEPEDLSAHRRPEVDEKPFVCVQCGKTFNNTSNLRTHQRIHTGEKPYQCSECGKSFSRSSNRIRHERIHLEEKHYKCPNCEQSFRRHADLTTHQQDHLGRRPFRCDLCGKSFGQSSALAVHYRTHLEPAPYICCECGKSFSNSSSFGVHHRTHTGERPYECTECGRTFSDISNFGAHQRTHRGEKPYRCTACGKHFSRSSNLIRHQKTHRGEQAGRESS", "length": 400, "header": "tr|F1N5Q1-1|F1N5Q1_BOVIN Isoform 1 of Zinc finger protein 691 OS=Bos taurus OX=9913 GN=ZNF691 PE=3 SV=2 CANONICAL=F1N5Q1-1" }, "isoforms": [ { "isoform_ac": "A0AAA9TND3-1", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TND3/entry", "sequence": { "sequence": "MGSEKEQSPEQHLPEEGERGNKPWRVDDSKVPDGEKEPGQANPSEAPQGPSPEEPTQEVAVSAAEPEDLSAHRRPEVDEKPFVCVQCGKTFNNTSNLRTHQRIHTGEKPYQCSECGKSFSRSSNRIRHERIHLEEKHYKCPNCEQSFRRHADLTTHQQDHLGRRPFRCDLCGKSFGQSSALAVHYRTHLEPAPYICCECGKSFSNSSSFGVHHRTHTGERPYECTECGRTFSDISNFGAHQRTHRGEKPYRCTACGKHFSRSSNLIRHQKTHRGEQAGRESS", "length": 282, "header": "tr|A0AAA9TND3-1|F1N5Q1_BOVIN Computationally mapped isoform of Zinc finger protein 691 OS=Bos taurus OX=9913 GN=ZNF691 PE=3 SV=1 CANONICAL=F1N5Q1-1" }, "locus": { "chromosome": "3", "start_pos": 103391537, "end_pos": 103390692, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000130648.2", "url": "https://www.ensembl.org/id/ENSBTAT00000130648.2" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000083018.1", "url": "https://www.ensembl.org/id/ENSBTAP00000083018.1" } ] } }, { "isoform_ac": "F1N5Q1-1", "url": "https://www.uniprot.org/uniprotkb/F1N5Q1/entry", "sequence": { "sequence": "MVGSPSVSVPVLLIHPASPDSKTTFSMKLLIPELFREICLCHQNSHGTVFITGVALKSTGFGAMGMAPSSATHLVCALGRITSFLLRLELNLLHLHDSFWSWWPMTLHCTIKSFRGSEMGSEKEQSPEQHLPEEGERGNKPWRVDDSKVPDGEKEPGQANPSEAPQGPSPEEPTQEVAVSAAEPEDLSAHRRPEVDEKPFVCVQCGKTFNNTSNLRTHQRIHTGEKPYQCSECGKSFSRSSNRIRHERIHLEEKHYKCPNCEQSFRRHADLTTHQQDHLGRRPFRCDLCGKSFGQSSALAVHYRTHLEPAPYICCECGKSFSNSSSFGVHHRTHTGERPYECTECGRTFSDISNFGAHQRTHRGEKPYRCTACGKHFSRSSNLIRHQKTHRGEQAGRESS", "length": 400, "header": "tr|F1N5Q1-1|F1N5Q1_BOVIN Isoform 1 of Zinc finger protein 691 OS=Bos taurus OX=9913 GN=ZNF691 PE=3 SV=2 CANONICAL=F1N5Q1-1" }, "locus": { "chromosome": "3", "start_pos": 103394565, "end_pos": 103390692, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000021332.5", "url": "https://www.ensembl.org/id/ENSBTAT00000021332.5" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000021332.4", "url": "https://www.ensembl.org/id/ENSBTAP00000021332.4" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [], "orthologs": [ { "uniprot_canonical_ac": "A0A5G2QQN2-1", "protein_name": "Zinc finger protein 691", "gene_name": "ZNF691", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MIRCVITTGSEMGSEKEQSPERHLPEEGERGSKPRSVDASEGFRIPDGEKEHGQESLSERPQGDRRKEPWRRVTVPAREPDVRPAPPRPEADEKPFVCAQCGKTFSNTSNLRTHQRIHTGEKPYKCSECGKSFSRSSNRIRHERIHLEEKHYKCPNCEESFRRHSDLTTHQQDHLGRRPFRCDLCSKSFGQSSALAVHYRTHLEPAPYICCECGKSFSNSSSFGVHHRTHTGERPYECAECGRTFSDISNFGAHQRTHRGERPYRCTLCGKHFSRSSNLIRHQKTHRGEQAGKGSG", "length": 296 }, "evidence": [ { "id": "F1N5Q1", "url": "https://omabrowser.org/oma/group/F1N5Q1/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "D3Z9R6-1", "protein_name": "Zinc finger protein 691", "gene_name": "Ermap", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MSVHMERLSPSGSWLVGCLFTIAIFQLPAQGSGSADKFYMAPLGSTANLSCPLRLWPNMAISQMRWHRPTHPPHPQAVHMFQDGQNSTEDLMPEYKGRTALVRDAHKGSYILQISNVRFEDRGLYQCQVWVGNSSQEDNVTLQVAVLGSDPYIHVKGYDAGWMELVCQSMGWFPEPRTEWRDPTGKALLSLSETHTLDEAGLFRTAVSSRIRGNALGNVSCTIRNKVLGQEKTTAMLITAPDPGSLSSPAVALSVVLPILGLLILLGIGLLCKQKKSREKLLYEQVMEVENLLEDHAKEKGRLHKALKKLRSELKLKRAAANAGWRRARLHFVAVTLDPDTAHPKLVLSEDRRCVRLGNRKRSVPDNPERFDFVVSVLGSEYFTTGCHYWEVYVGEKTKWILGVCSESVSRKGKVTASPANGHWLVRQSRGNEYEALTSPQTSFRLKESPKCVGIFLDYEAGVISFFNVTDKSHIFTFTHTFSSPLRPFFEPCLHDEGKNTAPLIICTELQKSEESIAPKQEGKGRANGDVSLKGPEMGSEKEQSPGAHLPEEGEGAKPWRVDDSKDSQTTSGEEHGQESLLEGLHEQHSQKPWRKVTTQAGGPGDPMTFSSPETDEKPFTCAQCGKAFNNTSNLRTHQRIHTGEKPYKCSECGKSFSRSSNRIRHERIHLEEKHYQCARCQESFRRRSDLTTHQQDHLGQRPYRCDICGKSFSQSSTLAVHHRTHLEPAPYICCECGKSFSNSSSFGVHHRTHTGERPYECTECGRTFSDISNFGAHQRTHRGERPYRCTLCGKHFSRSSNLIRHQKTHLGEQDEKDSS", "length": 820 }, "evidence": [ { "id": "F1N5Q1", "url": "https://omabrowser.org/oma/group/F1N5Q1/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "G3HFF1-1", "protein_name": "Zinc finger protein 691", "gene_name": "Znf691", "tax_id": 10029, "organism": "Cricetulus griseus", "sequence": { "sequence": "MGSEKEQSPEAHLPEEGEAGKPWRVDGSEGSQIAYGEEHGQTSLSKGLQGTHPKTPCQKVTARAGGPGKPIAFSSPEADEKPFICVQCGKTFNNTSNLRTHQRIHTGEKPYKCSECGKSFSRSSNRIRHERIHLEEKHYQCAKCQESFRRRSDLTTHQQDHLGQRPYRCDICGKSFSQSATLAVHHRTHLEPAPYICCECGKSFSNSSSFGVHHRTHTGERPYECTECGRTFSDISNFGAHQRTHRGEKPYRCTLCGKHFSRSSNLIRHQKTHLGEQDEKDSS", "length": 283 }, "evidence": [ { "id": "F1N5Q1", "url": "https://omabrowser.org/oma/group/F1N5Q1/", "database": "OMA" } ], "glygen_name": "Hamster", "common_name": "Chinese hamster" }, { "uniprot_canonical_ac": "Q3TDE8-1", "protein_name": "Zinc finger protein 691", "gene_name": "Znf691", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MGSEKEQRPEAHLPEEGEGAKPWRVDGSKDSQITPREDHGQESLLAGLHGTHPPKTRQKVTAQAGGPGDPMLFSSPETDEKLFICAQCGKTFNNTSNLRTHQRIHTGEKPYKCSECGKSFSRSSNRIRHERIHLEEKHYQCAKCQESFRRRSDLTTHQQDHLGQRPYRCDICGKSFTQSSTLAVHHRTHLEPAPYICCECGKSFSNSSSFGVHHRTHTGERPYECTECGRTFSDISNFGAHQRTHRGEKPYRCTLCGKHFSRSSNLIRHQKTHLGEQDEKDFS", "length": 283 }, "evidence": [ { "id": "F1N5Q1", "url": "https://omabrowser.org/oma/group/F1N5Q1/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q5VV52-2", "protein_name": "Zinc finger protein 691", "gene_name": "ZNF691", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MSLCSPTHSAEMSLFLQGPEEMLPLSSEGSEMGSEKEQSPEPHLPEEGEGGKPWRVDDSEGSWIPPGEKEHGQESLSDELQETHPKKPWQKVTVRARELGDPIAHPRHEADEKPFICAQCGKTFNNTSNLRTHQRIHTGEKPYKCSECGKSFSRSSNRIRHERIHLEEKHYKCPKCQESFRRRSDLTTHQQDHLGKRPYRCDICGKSFSQSATLAVHHRTHLEPAPYICCECGKSFSNSSSFGVHHRTHTGERPYECTECGRTFSDISNFGAHQRTHRGEKPYRCTVCGKHFSRSSNLIRHQKTHLGEQAGKDSS", "length": 315 }, "evidence": [ { "id": "F1N5Q1", "url": "https://omabrowser.org/oma/group/F1N5Q1/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" } ], "go_annotation": { "categories": [ { "name": "Molecular Function", "total": 4, "go_terms": [ { "name": "DNA binding", "id": "GO:0003677", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003677", "evidence": [ { "database": "UniProtKB", "id": "F1N5Q1", "url": "https://www.uniprot.org/uniprotkb/F1N5Q1" } ], "pmid": "" }, { "name": "zinc ion binding", "id": "GO:0008270", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008270", "evidence": [ { "database": "UniProtKB", "id": "F1N5Q1", "url": "https://www.uniprot.org/uniprotkb/F1N5Q1" } ], "pmid": "" }, { "name": "RNA polymerase II cis-regulatory region sequence-specific DNA binding", "id": "GO:0000978", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000978", "evidence": [ { "database": "UniProtKB", "id": "F1N5Q1", "url": "https://www.uniprot.org/uniprotkb/F1N5Q1" } ], "pmid": "" }, { "name": "DNA-binding transcription factor activity, RNA polymerase II-specific", "id": "GO:0000981", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000981", "evidence": [ { "database": "UniProtKB", "id": "F1N5Q1", "url": "https://www.uniprot.org/uniprotkb/F1N5Q1" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 1, "go_terms": [ { "name": "nucleus", "id": "GO:0005634", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005634", "evidence": [ { "database": "UniProtKB", "id": "F1N5Q1", "url": "https://www.uniprot.org/uniprotkb/F1N5Q1" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 2, "go_terms": [ { "name": "DNA-templated transcription", "id": "GO:0006351", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006351", "evidence": [ { "database": "UniProtKB", "id": "F1N5Q1", "url": "https://www.uniprot.org/uniprotkb/F1N5Q1" } ], "pmid": "" }, { "name": "regulation of transcription by RNA polymerase II", "id": "GO:0006357", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006357", "evidence": [ { "database": "UniProtKB", "id": "F1N5Q1", "url": "https://www.uniprot.org/uniprotkb/F1N5Q1" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 210, "end_pos": 212, "annotation": "n_glycosylation_sequon" }, { "start_pos": 211, "end_pos": 213, "annotation": "n_glycosylation_sequon" }, { "start_pos": 323, "end_pos": 325, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [ { "pdb_id": "AF-F1N5Q1-F1", "pdb_chain": "global", "start_pos": 1, "end_pos": 400, "overlap": "1.0", "method": "AlphaFold", "type": "alphafold", "resolution": -1.0, "url": "https://data.glygen.org/ln2downloads/pdb/current/AF-F1N5Q1-F1.pdb", "url_external": "https://alphafold.ebi.ac.uk/entry/F1N5Q1" } ], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "F1N5Q1", "database": "UniProtKB", "url": 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"length": 1081, "header": "tr|F6Q5Z6-1|F6Q5Z6_BOVIN Isoform 1 of Mitotic checkpoint serine/threonine-protein kinase BUB1 OS=Bos taurus OX=9913 GN=BUB1 PE=4 SV=1 CANONICAL=F6Q5Z6-1" }, "locus": { "chromosome": "11", "start_pos": 1618151, "end_pos": 1585485, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000028226.7", "url": "https://www.ensembl.org/id/ENSBTAT00000028226.7" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000028226.5", "url": "https://www.ensembl.org/id/ENSBTAP00000028226.5" } ] } } ], "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "other", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 197, "start_aa": "Thr", "end_pos": 197, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr197", "evidence": [ { "id": 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"database": "UniProtKB", "id": "F6Q5Z6", "url": "https://www.uniprot.org/uniprotkb/F6Q5Z6" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 4, "go_terms": [ { "name": "nucleus", "id": "GO:0005634", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005634", "evidence": [ { "database": "UniProtKB", "id": "F6Q5Z6", "url": "https://www.uniprot.org/uniprotkb/F6Q5Z6" } ], "pmid": "" }, { "name": "kinetochore", "id": "GO:0000776", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000776", "evidence": [ { "database": "UniProtKB", "id": "F6Q5Z6", "url": "https://www.uniprot.org/uniprotkb/F6Q5Z6" } ], "pmid": "" }, { "name": "nucleoplasm", "id": "GO:0005654", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005654", "evidence": [ { "database": "UniProtKB", "id": "F6Q5Z6", "url": "https://www.uniprot.org/uniprotkb/F6Q5Z6" } ], "pmid": "" }, { "name": "outer kinetochore", "id": "GO:0000940", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000940", "evidence": [ { "database": "UniProtKB", "id": "F6Q5Z6", "url": "https://www.uniprot.org/uniprotkb/F6Q5Z6" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 5, "go_terms": [ { "name": "chromosome segregation", "id": "GO:0007059", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007059", "evidence": [ { "database": "UniProtKB", "id": "F6Q5Z6", "url": "https://www.uniprot.org/uniprotkb/F6Q5Z6" } ], "pmid": "" }, { "name": "cell division", "id": "GO:0051301", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0051301", "evidence": [ { "database": "UniProtKB", "id": "F6Q5Z6", "url": "https://www.uniprot.org/uniprotkb/F6Q5Z6" } ], "pmid": "" }, { "name": "apoptotic process", "id": "GO:0006915", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006915", "evidence": [ { "database": "UniProtKB", "id": "F6Q5Z6", "url": "https://www.uniprot.org/uniprotkb/F6Q5Z6" } ], "pmid": "" }, { "name": "mitotic spindle assembly checkpoint signaling", "id": "GO:0007094", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007094", "evidence": [ { 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"L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A3Q1M9F0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1M9F0" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A3Q1M9F0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1M9F0" } ] } ] }, { "uniprot_ac": "A0A3Q1M9L7", "gene_name": "MAP4K5", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A3Q1M9L7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1M9L7" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A3Q1M9L7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1M9L7" } ] } ] }, { "uniprot_ac": "A0A3Q1MA37", "gene_name": "CDC42BPG", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A3Q1MA37", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1MA37" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A3Q1MA37", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1MA37" } ] } ] }, { "uniprot_ac": "A0A3Q1MD82", "gene_name": "CDK16", "activity": [ { "ec_number": "2.7.11.22", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A3Q1MD82", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1MD82" } ] }, { "ec_number": "2.7.11.22", "activity": "", "evidence": [ { "id": "A0A3Q1MD82", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1MD82" } ] } ] }, { "uniprot_ac": "A0A3Q1MEZ6", "gene_name": "MTOR", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A3Q1MEZ6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1MEZ6" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A3Q1MEZ6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1MEZ6" } ] } ] }, { "uniprot_ac": "A0A3Q1MHH5", "gene_name": "MAP3K9", "activity": [ { "ec_number": "2.7.11.25", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A3Q1MHH5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1MHH5" } ] }, { "ec_number": "2.7.11.25", "activity": "", "evidence": [ { "id": "A0A3Q1MHH5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1MHH5" } ] } ] }, { "uniprot_ac": "A0A3Q1MHL3", "gene_name": "LIMK2", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A3Q1MHL3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1MHL3" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A3Q1MHL3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1MHL3" } ] } ] }, { "uniprot_ac": "A0A3Q1MHM3", "gene_name": "HIPK2", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A3Q1MHM3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1MHM3" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A3Q1MHM3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1MHM3" } ] } ] }, { "uniprot_ac": "A0A3Q1MI36", "gene_name": "", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A3Q1MI36", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1MI36" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A3Q1MI36", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1MI36" } ] } ] }, { "uniprot_ac": "A0A3Q1MKC7", "gene_name": "CAMK2A", "activity": [ { "ec_number": "2.7.11.17", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A3Q1MKC7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1MKC7" } ] }, { "ec_number": "2.7.11.17", "activity": "", "evidence": [ { "id": "A0A3Q1MKC7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1MKC7" } ] } ] }, { "uniprot_ac": "A0A3Q1MLK5", "gene_name": "LMTK2", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A3Q1MLK5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1MLK5" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A3Q1MLK5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1MLK5" } ] } ] }, { "uniprot_ac": "A0A3Q1MNB4", "gene_name": "STK32A", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A3Q1MNB4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1MNB4" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A3Q1MNB4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1MNB4" } ] } ] }, { "uniprot_ac": "A0A3Q1MRR6", "gene_name": "PRKCD", "activity": [ { "ec_number": "2.7.11.13", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A3Q1MRR6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1MRR6" } ] }, { "ec_number": "2.7.11.13", "activity": "", "evidence": [ { "id": "A0A3Q1MRR6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1MRR6" } ] } ] }, { "uniprot_ac": "A0A3Q1MRW3", "gene_name": "SNRK", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A3Q1MRW3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1MRW3" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A3Q1MRW3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1MRW3" } ] } ] }, { "uniprot_ac": "A0A3Q1MS69", "gene_name": "NEK2", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A3Q1MS69", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1MS69" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A3Q1MS69", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1MS69" } ] } ] }, { "uniprot_ac": "A0A3Q1MUZ6", "gene_name": "MARK4", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A3Q1MUZ6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1MUZ6" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A3Q1MUZ6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1MUZ6" } ] } ] }, { "uniprot_ac": "A0A3Q1MW77", "gene_name": "ROCK2", "activity": [ { "ec_number": "2.7.11.39", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A3Q1MW77", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1MW77" } ] }, { "ec_number": "2.7.11.39", "activity": "", "evidence": [ { "id": "A0A3Q1MW77", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1MW77" } ] } ] }, { "uniprot_ac": "A0A3Q1MXI5", "gene_name": "DAPK1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A3Q1MXI5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1MXI5" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A3Q1MXI5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1MXI5" } ] } ] }, { "uniprot_ac": "A0A3Q1N4A7", "gene_name": "CIT", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A3Q1N4A7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1N4A7" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A3Q1N4A7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1N4A7" } ] } ] }, { "uniprot_ac": "A0A3Q1N707", "gene_name": "WNK4", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A3Q1N707", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1N707" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A3Q1N707", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1N707" } ] } ] }, { "uniprot_ac": "A0A3Q1N860", "gene_name": "RPS6KL1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A3Q1N860", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1N860" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A3Q1N860", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1N860" } ] } ] }, { "uniprot_ac": "A0A3Q1N9F5", "gene_name": "PRKD1", "activity": [ { "ec_number": "2.7.11.13", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A3Q1N9F5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1N9F5" } ] }, { "ec_number": "2.7.11.13", "activity": "", "evidence": [ { "id": "A0A3Q1N9F5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1N9F5" } ] } ] }, { "uniprot_ac": "A0A3Q1NBC4", "gene_name": "SRPK2", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A3Q1NBC4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1NBC4" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A3Q1NBC4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1NBC4" } ] } ] }, { "uniprot_ac": "A0A3Q1NFM1", "gene_name": "LOC100138998", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A3Q1NFM1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1NFM1" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A3Q1NFM1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1NFM1" } ] } ] }, { "uniprot_ac": "A0A3Q1NKC2", "gene_name": "CAMK2G", "activity": [ { "ec_number": "2.7.11.17", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A3Q1NKC2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1NKC2" } ] }, { "ec_number": "2.7.11.17", "activity": "", "evidence": [ { "id": "A0A3Q1NKC2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1NKC2" } ] } ] }, { "uniprot_ac": "A0A3S5ZPR2", "gene_name": "MELK", "activity": [ { "ec_number": "2.7.10.2", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A3S5ZPR2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3S5ZPR2" } ] }, { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A3S5ZPR2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3S5ZPR2" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A3S5ZPR2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3S5ZPR2" } ] }, { "ec_number": "2.7.10.2", "activity": "", "evidence": [ { "id": "A0A3S5ZPR2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3S5ZPR2" } ] } ] }, { "uniprot_ac": "A0AAA9RSJ2", "gene_name": "MKNK2", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0AAA9RSJ2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9RSJ2" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0AAA9RSJ2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9RSJ2" } ] } ] }, { "uniprot_ac": "A0AAA9RSQ6", "gene_name": "TRPM6", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0AAA9RSQ6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9RSQ6" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0AAA9RSQ6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9RSQ6" } ] } ] }, { "uniprot_ac": "A0AAA9RTJ4", "gene_name": "PIKFYVE", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0AAA9RTJ4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9RTJ4" } ] }, { "ec_number": "2.7.1.150", "activity": "a 1,2-diacyl-sn-glycero-3-phospho-(1D-myo-inositol-3-phosphate) + ATP = a 1,2-diacyl-sn-glycero-3-phospho-(1D-myo-inositol-3,5-bisphosphate) + ADP + H(+).", "evidence": [ { "id": "A0AAA9RTJ4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9RTJ4" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0AAA9RTJ4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9RTJ4" } ] }, { "ec_number": "2.7.1.150", "activity": "", "evidence": [ { "id": "A0AAA9RTJ4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9RTJ4" } ] } ] }, { "uniprot_ac": "A0AAA9RVB1", "gene_name": "TAOK2", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0AAA9RVB1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9RVB1" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0AAA9RVB1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9RVB1" } ] } ] }, { "uniprot_ac": "A0AAA9RW51", "gene_name": "AATK", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0AAA9RW51", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9RW51" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0AAA9RW51", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9RW51" } ] } ] }, { "uniprot_ac": "A0AAA9RWB8", "gene_name": "TRIO", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0AAA9RWB8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9RWB8" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0AAA9RWB8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9RWB8" } ] } ] }, { "uniprot_ac": "A0AAA9RWC6", "gene_name": "CHEK2", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0AAA9RWC6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9RWC6" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0AAA9RWC6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9RWC6" } ] } ] }, { "uniprot_ac": "A0AAA9S2N3", "gene_name": "CDKL4", "activity": [ { "ec_number": "2.7.11.22", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0AAA9S2N3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9S2N3" } ] }, { "ec_number": "2.7.11.22", "activity": "", "evidence": [ { "id": "A0AAA9S2N3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9S2N3" } ] } ] }, { "uniprot_ac": "A0AAA9S472", "gene_name": "MAPK8", "activity": [ { "ec_number": "2.7.11.24", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0AAA9S472", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9S472" } ] }, { "ec_number": "2.7.11.24", "activity": "", "evidence": [ { "id": "A0AAA9S472", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9S472" } ] } ] }, { "uniprot_ac": "A0AAA9S4Z4", "gene_name": "AKT1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0AAA9S4Z4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9S4Z4" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0AAA9S4Z4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9S4Z4" } ] } ] }, { "uniprot_ac": "A0AAA9S5X7", "gene_name": "AURKB", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0AAA9S5X7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9S5X7" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0AAA9S5X7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9S5X7" } ] } ] }, { "uniprot_ac": "A0AAA9S663", "gene_name": "PDPK1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0AAA9S663", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9S663" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0AAA9S663", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9S663" } ] } ] }, { "uniprot_ac": "A0AAA9S954", "gene_name": "CAMKK1", "activity": [ { "ec_number": "2.7.11.17", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0AAA9S954", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9S954" } ] }, { "ec_number": "2.7.11.17", "activity": "", "evidence": [ { "id": "A0AAA9S954", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9S954" } ] } ] }, { "uniprot_ac": "A0AAA9S9A9", "gene_name": "NEK11", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0AAA9S9A9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9S9A9" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0AAA9S9A9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9S9A9" } ] } ] }, { "uniprot_ac": "A0AAA9SG01", "gene_name": "ERN1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0AAA9SG01", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9SG01" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0AAA9SG01", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9SG01" } ] } ] }, { "uniprot_ac": "A0AAA9SGM8", "gene_name": "MKNK1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0AAA9SGM8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9SGM8" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0AAA9SGM8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9SGM8" } ] } ] }, { "uniprot_ac": "A0AAA9SH90", "gene_name": "DAPK2", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0AAA9SH90", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9SH90" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0AAA9SH90", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9SH90" } ] } ] }, { "uniprot_ac": "A0AAA9SIK7", "gene_name": "NEK10", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0AAA9SIK7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9SIK7" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0AAA9SIK7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9SIK7" } ] } ] }, { "uniprot_ac": "A0AAA9SJ92", "gene_name": "RPS6KA1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0AAA9SJ92", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9SJ92" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0AAA9SJ92", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9SJ92" } ] } ] }, { "uniprot_ac": "A0AAA9SJA3", "gene_name": "TTBK2", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0AAA9SJA3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9SJA3" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0AAA9SJA3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9SJA3" } ] } ] }, { "uniprot_ac": "A0AAA9SJQ0", "gene_name": "RPS6KA4", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0AAA9SJQ0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9SJQ0" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0AAA9SJQ0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9SJQ0" } ] } ] }, { "uniprot_ac": "A0AAA9SK35", "gene_name": "PRKG2", "activity": [ { "ec_number": "2.7.11.12", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0AAA9SK35", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9SK35" } ] }, { "ec_number": "2.7.11.12", "activity": "", "evidence": [ { "id": "A0AAA9SK35", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9SK35" } ] } ] }, { "uniprot_ac": "A0AAA9SKK8", "gene_name": "MAP3K4", "activity": [ { "ec_number": "2.7.11.25", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0AAA9SKK8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9SKK8" } ] }, { "ec_number": "2.7.11.25", "activity": "", "evidence": [ { "id": "A0AAA9SKK8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9SKK8" } ] } ] }, { "uniprot_ac": "A0AAA9SLY1", "gene_name": "NEK5", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0AAA9SLY1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9SLY1" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0AAA9SLY1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9SLY1" } ] } ] }, { "uniprot_ac": "A0AAA9SMH0", "gene_name": "DCLK3", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0AAA9SMH0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9SMH0" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0AAA9SMH0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9SMH0" } ] } ] }, { "uniprot_ac": "A0AAA9SMT9", "gene_name": "MAP3K12", "activity": [ { "ec_number": "2.7.11.25", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0AAA9SMT9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9SMT9" } ] }, { "ec_number": "2.7.11.25", "activity": "", "evidence": [ { "id": "A0AAA9SMT9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9SMT9" } ] } ] }, { "uniprot_ac": "A0AAA9SNP6", "gene_name": "MOS", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0AAA9SNP6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9SNP6" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0AAA9SNP6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9SNP6" } ] } ] }, { "uniprot_ac": "A0AAA9SU81", "gene_name": "PRKAA2", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0AAA9SU81", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9SU81" } ] }, { "ec_number": "2.7.11.31", "activity": "L-seryl-[acetyl-CoA carboxylase] + ATP = O-phospho-L-seryl-[acetyl-CoA carboxylase] + ADP + H(+).", "evidence": [ { "id": "A0AAA9SU81", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9SU81" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0AAA9SU81", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9SU81" } ] }, { "ec_number": "2.7.11.31", "activity": "", "evidence": [ { "id": "A0AAA9SU81", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9SU81" } ] } ] }, { "uniprot_ac": "A0AAA9SVM5", "gene_name": "MAP3K3", "activity": [ { "ec_number": "2.7.11.25", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0AAA9SVM5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9SVM5" } ] }, { "ec_number": "2.7.11.25", "activity": "", "evidence": [ { "id": "A0AAA9SVM5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9SVM5" } ] } ] }, { "uniprot_ac": "A0AAA9SWA1", "gene_name": "STK26", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0AAA9SWA1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9SWA1" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0AAA9SWA1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9SWA1" } ] } ] }, { "uniprot_ac": "A0AAA9SX77", "gene_name": "CDK14", "activity": [ { "ec_number": "2.7.11.22", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0AAA9SX77", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9SX77" } ] }, { "ec_number": "2.7.11.22", "activity": "", "evidence": [ { "id": "A0AAA9SX77", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9SX77" } ] } ] }, { "uniprot_ac": "A0AAA9SXE3", "gene_name": "MAP3K6", "activity": [ { "ec_number": "2.7.11.25", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0AAA9SXE3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9SXE3" } ] }, { "ec_number": "2.7.11.25", "activity": "", "evidence": [ { "id": "A0AAA9SXE3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9SXE3" } ] } ] }, { "uniprot_ac": "A0AAA9SYW5", "gene_name": "NEK3", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0AAA9SYW5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9SYW5" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0AAA9SYW5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9SYW5" } ] } ] }, { "uniprot_ac": "A0AAA9T042", "gene_name": "DYRK4", "activity": [ { "ec_number": "2.7.12.1", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0AAA9T042", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9T042" } ] }, { "ec_number": "2.7.12.1", "activity": "", "evidence": [ { "id": "A0AAA9T042", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9T042" } ] } ] }, { "uniprot_ac": "A0AAA9T2F0", "gene_name": "BRAF", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0AAA9T2F0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9T2F0" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0AAA9T2F0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9T2F0" } ] } ] }, { "uniprot_ac": "A0AAA9T3H7", "gene_name": "TNK1", "activity": [ { "ec_number": "2.7.10.2", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0AAA9T3H7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9T3H7" } ] }, { "ec_number": "2.7.10.2", "activity": "", "evidence": [ { "id": "A0AAA9T3H7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9T3H7" } ] } ] }, { "uniprot_ac": "A0AAA9T3K7", "gene_name": "WNK3", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0AAA9T3K7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9T3K7" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0AAA9T3K7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9T3K7" } ] } ] }, { "uniprot_ac": "A0AAA9T584", "gene_name": "CSNK1G3", "activity": 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= O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0AAA9T5C9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9T5C9" } ] }, { "ec_number": "2.7.11.24", "activity": "", "evidence": [ { "id": "A0AAA9T5C9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9T5C9" } ] } ] }, { "uniprot_ac": "A0AAA9T7I8", "gene_name": "TSSK2", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0AAA9T7I8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9T7I8" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0AAA9T7I8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9T7I8" } ] } ] }, { "uniprot_ac": "A0AAA9T7L6", "gene_name": "RPS6KC1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0AAA9T7L6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9T7L6" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0AAA9T7L6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9T7L6" } ] } ] }, { "uniprot_ac": "A0AAA9T7Z7", "gene_name": "RPS6KA5", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0AAA9T7Z7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9T7Z7" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0AAA9T7Z7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9T7Z7" } ] } ] }, { "uniprot_ac": "A0AAA9T8T9", "gene_name": "MARK2", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0AAA9T8T9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9T8T9" } ] }, { "ec_number": "2.7.11.26", "activity": "L-seryl-[tau protein] + ATP = O-phospho-L-seryl-[tau protein] + ADP + H(+).", "evidence": [ { "id": "A0AAA9T8T9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9T8T9" } ] }, { "ec_number": "2.7.11.26", "activity": "", "evidence": [ { "id": "A0AAA9T8T9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9T8T9" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0AAA9T8T9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9T8T9" } ] } ] }, { "uniprot_ac": "A0AAA9T8Z3", "gene_name": "STK32C", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0AAA9T8Z3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9T8Z3" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0AAA9T8Z3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9T8Z3" } ] } ] }, { "uniprot_ac": "A0AAA9T940", "gene_name": "PLK2", "activity": [ { "ec_number": "2.7.11.21", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0AAA9T940", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9T940" } ] }, { "ec_number": "2.7.11.21", "activity": "", "evidence": [ { "id": "A0AAA9T940", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9T940" } ] } ] }, { "uniprot_ac": "A0AAA9TCI9", "gene_name": "MOK", "activity": [ { "ec_number": "2.7.11.22", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0AAA9TCI9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TCI9" } ] }, { "ec_number": "2.7.11.22", "activity": "", "evidence": [ { "id": "A0AAA9TCI9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TCI9" } ] } ] }, { "uniprot_ac": "A0AAA9TD48", "gene_name": "DYRK1B", "activity": [ { "ec_number": "2.7.12.1", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0AAA9TD48", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TD48" } ] }, { "ec_number": "2.7.12.1", "activity": "", "evidence": [ { "id": "A0AAA9TD48", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TD48" } ] } ] }, { "uniprot_ac": "A0AAA9TDL1", "gene_name": "SBK1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0AAA9TDL1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TDL1" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0AAA9TDL1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TDL1" } ] } ] }, { "uniprot_ac": "A0AAA9TJD5", "gene_name": "", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0AAA9TJD5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TJD5" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0AAA9TJD5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TJD5" } ] } ] }, { "uniprot_ac": "A0AAA9TLV0", "gene_name": "STK32B", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0AAA9TLV0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TLV0" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0AAA9TLV0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TLV0" } ] } ] }, { "uniprot_ac": "A0AAA9TMV7", "gene_name": "SMG1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0AAA9TMV7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TMV7" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0AAA9TMV7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TMV7" } ] } ] }, { "uniprot_ac": "A0AAA9TNE6", "gene_name": "TLK2", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0AAA9TNE6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TNE6" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0AAA9TNE6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TNE6" } ] } ] }, { "uniprot_ac": "A0AAA9TNL3", "gene_name": "SLK", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0AAA9TNL3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TNL3" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0AAA9TNL3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TNL3" } ] } ] }, { "uniprot_ac": "A0AAA9TP92", "gene_name": "CAMK1", "activity": [ { "ec_number": "2.7.11.17", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0AAA9TP92", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TP92" } ] }, { "ec_number": "2.7.11.17", "activity": "", "evidence": [ { "id": "A0AAA9TP92", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TP92" } ] } ] }, { "uniprot_ac": "A0AAA9TU12", "gene_name": "PRKCQ", "activity": [ { "ec_number": "2.7.11.13", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0AAA9TU12", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TU12" } ] }, { "ec_number": "2.7.11.13", "activity": "", "evidence": [ { "id": "A0AAA9TU12", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TU12" } ] } ] }, { "uniprot_ac": "A0AAA9TVT5", "gene_name": "CASK", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0AAA9TVT5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TVT5" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0AAA9TVT5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TVT5" } ] } ] }, { "uniprot_ac": "A0AAA9TWW0", "gene_name": "TBK1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0AAA9TWW0", "database": "UniProtKB", "url": 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"ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0AAA9U1A4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9U1A4" } ] } ] }, { "uniprot_ac": "A0AAA9U1M9", "gene_name": "DMPK", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0AAA9U1M9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9U1M9" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0AAA9U1M9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9U1M9" } ] } ] }, { "uniprot_ac": "A0AAA9U1R3", "gene_name": "DCLK2", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0AAA9U1R3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9U1R3" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0AAA9U1R3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9U1R3" } ] } ] }, { "uniprot_ac": "A0AAF6DLR2", "gene_name": "CDK18", "activity": [ { "ec_number": "2.7.11.22", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0AAF6DLR2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAF6DLR2" } ] }, { "ec_number": "2.7.11.22", "activity": "", "evidence": [ { "id": "A0AAF6DLR2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAF6DLR2" } ] } ] }, { "uniprot_ac": "A0AAF6DMH7", "gene_name": "RIPK1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0AAF6DMH7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAF6DMH7" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0AAF6DMH7", "database": "UniProtKB", "url": 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"database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAF6YMX3" } ] }, { "ec_number": "2.7.11.22", "activity": "", "evidence": [ { "id": "A0AAF6YMX3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAF6YMX3" } ] }, { "ec_number": "2.7.11.23", "activity": "", "evidence": [ { "id": "A0AAF6YMX3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAF6YMX3" } ] } ] }, { "uniprot_ac": "A0AAF6Z257", "gene_name": "IRAK1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0AAF6Z257", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAF6Z257" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0AAF6Z257", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAF6Z257" } ] } ] }, { "uniprot_ac": "A0ABI0NJ75", "gene_name": "PAK6", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0ABI0NJ75", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NJ75" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0ABI0NJ75", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NJ75" } ] } ] }, { "uniprot_ac": "A0ABI0NM98", "gene_name": "KALRN", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0ABI0NM98", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NM98" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0ABI0NM98", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NM98" } ] } ] }, { "uniprot_ac": "A0ABI0NMT8", "gene_name": "PIK3CG", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0ABI0NMT8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NMT8" } ] }, { "ec_number": "2.7.1.153", "activity": "a 1,2-diacyl-sn-glycero-3-phospho-(1D-myo-inositol-4,5-bisphosphate) + ATP = a 1,2-diacyl-sn-glycero-3-phospho-(1D-myo-inositol-3,4,5-trisphosphate) + ADP + H(+).", "evidence": [ { "id": "A0ABI0NMT8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NMT8" } ] }, { "ec_number": "2.7.1.137", "activity": "a 1,2-diacyl-sn-glycero-3-phospho-(1D-myo-inositol) + ATP = a 1,2-diacyl-sn-glycero-3-phospho-(1D-myo-inositol-3-phosphate) + ADP + H(+).", "evidence": [ { "id": "A0ABI0NMT8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NMT8" } ] }, { "ec_number": "2.7.1.154", "activity": "a 1,2-diacyl-sn-glycero-3-phospho-(1D-myo-inositol 4-phosphate) + ATP = a 1,2-diacyl-sn-glycero-3-phospho-(1D-myo-inositol-3,4-bisphosphate) + ADP + H(+).", "evidence": [ { "id": "A0ABI0NMT8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NMT8" } ] }, { "ec_number": "2.7.1.153", "activity": "", "evidence": [ { "id": "A0ABI0NMT8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NMT8" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0ABI0NMT8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NMT8" } ] }, { "ec_number": "2.7.1.137", "activity": "", "evidence": [ { "id": "A0ABI0NMT8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NMT8" } ] }, { "ec_number": "2.7.1.154", "activity": "", "evidence": [ { "id": "A0ABI0NMT8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NMT8" } ] } ] }, { "uniprot_ac": "A0ABI0NQQ4", "gene_name": "PRKAA1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0ABI0NQQ4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NQQ4" } ] }, { "ec_number": "2.7.11.26", "activity": "L-seryl-[tau protein] + ATP = O-phospho-L-seryl-[tau protein] + ADP + H(+).", "evidence": [ { "id": "A0ABI0NQQ4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NQQ4" } ] }, { "ec_number": "2.7.11.31", "activity": "L-seryl-[acetyl-CoA carboxylase] + ATP = O-phospho-L-seryl-[acetyl-CoA carboxylase] + ADP + H(+).", "evidence": [ { "id": "A0ABI0NQQ4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NQQ4" } ] }, { "ec_number": "2.7.11.26", "activity": "", "evidence": [ { "id": "A0ABI0NQQ4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NQQ4" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0ABI0NQQ4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NQQ4" } ] }, { "ec_number": "2.7.11.31", "activity": "", "evidence": [ { "id": "A0ABI0NQQ4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NQQ4" } ] } ] }, { "uniprot_ac": "A0ABI0NRQ5", "gene_name": "LOC101905399", "activity": [ { "ec_number": "2.7.12.2", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0ABI0NRQ5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NRQ5" } ] }, { "ec_number": "2.7.12.2", "activity": "", "evidence": [ { "id": "A0ABI0NRQ5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NRQ5" } ] } ] }, { "uniprot_ac": "A0ABI0NS30", "gene_name": "PRKCA", "activity": [ { "ec_number": "2.7.11.13", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0ABI0NS30", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NS30" } ] }, { "ec_number": "2.7.11.13", "activity": "", "evidence": [ { "id": "A0ABI0NS30", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NS30" } ] } ] }, { "uniprot_ac": "A0ABI0NV47", "gene_name": "DCLK1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0ABI0NV47", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NV47" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0ABI0NV47", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NV47" } ] } ] }, { "uniprot_ac": "A0ABI0P0X3", "gene_name": "", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0ABI0P0X3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0ABI0P0X3" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0ABI0P0X3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0ABI0P0X3" } ] } ] }, { "uniprot_ac": "A0ABI0P2C0", "gene_name": "TSSK5", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0ABI0P2C0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0ABI0P2C0" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0ABI0P2C0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0ABI0P2C0" } ] } ] }, { "uniprot_ac": "A0ABI0P3N8", "gene_name": "", "activity": [ { "ec_number": "2.7.11.22", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0ABI0P3N8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0ABI0P3N8" } ] }, { "ec_number": "2.7.11.22", "activity": "", "evidence": [ { "id": "A0ABI0P3N8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0ABI0P3N8" } ] } ] }, { "uniprot_ac": "A0ABI0P3P6", "gene_name": "MAST4", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0ABI0P3P6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0ABI0P3P6" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0ABI0P3P6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0ABI0P3P6" } ] } ] }, { "uniprot_ac": "A0ABI0P443", "gene_name": "SGK2", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0ABI0P443", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0ABI0P443" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0ABI0P443", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0ABI0P443" } ] } ] }, { "uniprot_ac": "A1A4I4", "gene_name": "PKN1", "activity": [ { "ec_number": "2.7.11.13", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A1A4I4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A1A4I4" } ] }, { "ec_number": "2.7.11.13", "activity": "", "evidence": [ { "id": "A1A4I4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A1A4I4" } ] } ] }, { "uniprot_ac": "A2VDU3", "gene_name": "MAP3K7", "activity": [ { "ec_number": "2.7.11.25", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A2VDU3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A2VDU3" } ] }, { "ec_number": "2.7.11.25", "activity": "", "evidence": [ { "id": "A2VDU3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A2VDU3" } ] } ] }, { "uniprot_ac": "A2VDV2", "gene_name": "STK38", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A2VDV2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A2VDV2" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A2VDV2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A2VDV2" } ] } ] }, { "uniprot_ac": "A2VDZ4", "gene_name": "PLK4", "activity": [ { "ec_number": "2.7.11.21", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A2VDZ4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A2VDZ4" } ] }, { "ec_number": "2.7.11.21", "activity": "", "evidence": [ { "id": "A2VDZ4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A2VDZ4" } ] } ] }, { "uniprot_ac": "A5D791", "gene_name": "EIF2AK3", "activity": [ { "ec_number": "2.7.10.2", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "A5D791", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A5D791" } ] }, { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A5D791", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A5D791" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A5D791", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A5D791" } ] } ] }, { "uniprot_ac": "A5PKJ4", "gene_name": "MAPK7", "activity": [ { "ec_number": "2.7.11.24", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A5PKJ4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A5PKJ4" } ] }, { "ec_number": "2.7.11.24", "activity": "", "evidence": [ { "id": "A5PKJ4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A5PKJ4" } ] } ] }, { "uniprot_ac": "A7E3S4", "gene_name": "RAF1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A7E3S4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A7E3S4" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A7E3S4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A7E3S4" } ] } ] }, { "uniprot_ac": "A7E3X2", "gene_name": "CSNK1G1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A7E3X2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A7E3X2" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A7E3X2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A7E3X2" } ] } ] }, { "uniprot_ac": "A7MB74", "gene_name": "SGK1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A7MB74", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A7MB74" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A7MB74", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A7MB74" } ] } ] }, { "uniprot_ac": "A7MBB4", "gene_name": "MAP3K13", "activity": [ { "ec_number": "2.7.11.25", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A7MBB4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A7MBB4" } ] }, { "ec_number": "2.7.11.25", "activity": "", "evidence": [ { "id": "A7MBB4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A7MBB4" } ] } ] }, { "uniprot_ac": "E1B754", "gene_name": "MAST2", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "E1B754", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1B754" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "E1B754", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1B754" } ] } ] }, { "uniprot_ac": "E1B793", "gene_name": "STK36", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "E1B793", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1B793" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "E1B793", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1B793" } ] } ] }, { "uniprot_ac": "E1B7H4", "gene_name": "MAP3K10", "activity": [ { "ec_number": "2.7.11.25", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "E1B7H4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1B7H4" } ] }, { "ec_number": "2.7.11.25", "activity": "", "evidence": [ { "id": "E1B7H4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1B7H4" } ] } ] }, { "uniprot_ac": "E1B7L9", "gene_name": "PRKD3", "activity": [ { "ec_number": "2.7.11.13", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "E1B7L9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1B7L9" } ] }, { "ec_number": "2.7.11.13", "activity": "", "evidence": [ { "id": "E1B7L9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1B7L9" } ] } ] }, { "uniprot_ac": "E1B827", "gene_name": "NEK8", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "E1B827", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1B827" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "E1B827", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1B827" } ] } ] }, { "uniprot_ac": "E1B887", "gene_name": "RIOK1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "E1B887", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1B887" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "E1B887", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1B887" } ] } ] }, { "uniprot_ac": "E1B8J7", "gene_name": "ERN2", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "E1B8J7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1B8J7" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "E1B8J7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1B8J7" } ] } ] }, { "uniprot_ac": "E1B8P9", "gene_name": "MAPK3", "activity": [ { "ec_number": "2.7.11.24", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "E1B8P9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1B8P9" } ] }, { "ec_number": "2.7.11.24", "activity": "", "evidence": [ { "id": "E1B8P9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1B8P9" } ] } ] }, { "uniprot_ac": "E1B902", "gene_name": "MAP4K2", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "E1B902", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1B902" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "E1B902", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1B902" } ] } ] }, { "uniprot_ac": "E1B9B6", "gene_name": "NUAK1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "E1B9B6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1B9B6" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "E1B9B6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1B9B6" } ] } ] }, { "uniprot_ac": "E1B9F9", "gene_name": "LATS2", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "E1B9F9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1B9F9" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "E1B9F9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1B9F9" } ] } ] }, { "uniprot_ac": "E1B9Q2", "gene_name": "CLK2", "activity": [ { "ec_number": "2.7.12.1", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "E1B9Q2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1B9Q2" } ] }, { "ec_number": "2.7.12.1", "activity": "", "evidence": [ { "id": "E1B9Q2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1B9Q2" } ] } ] }, { "uniprot_ac": "E1BAL6", "gene_name": "EIF2AK4", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "E1BAL6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BAL6" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "E1BAL6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BAL6" } ] } ] }, { "uniprot_ac": "E1BB49", "gene_name": "HIPK4", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "E1BB49", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BB49" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "E1BB49", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BB49" } ] } ] }, { "uniprot_ac": "E1BB50", "gene_name": "CDK12", "activity": [ { "ec_number": "2.7.11.22", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "E1BB50", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BB50" } ] }, { "ec_number": "2.7.11.23", "activity": "[DNA-directed RNA polymerase] + ATP = phospho-[DNA-directed RNA polymerase] + ADP + H(+).", "evidence": [ { "id": "E1BB50", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BB50" } ] }, { "ec_number": "2.7.11.23", "activity": "", "evidence": [ { "id": "E1BB50", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BB50" } ] }, { "ec_number": "2.7.11.22", "activity": "", "evidence": [ { "id": "E1BB50", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BB50" } ] } ] }, { "uniprot_ac": "E1BB52", "gene_name": "CDK13", "activity": [ { "ec_number": "2.7.11.22", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "E1BB52", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BB52" } ] }, { "ec_number": "2.7.11.23", "activity": "[DNA-directed RNA polymerase] + ATP = phospho-[DNA-directed RNA polymerase] + ADP + H(+).", "evidence": [ { "id": "E1BB52", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BB52" } ] }, { "ec_number": "2.7.11.23", "activity": "", "evidence": [ { "id": "E1BB52", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BB52" } ] }, { "ec_number": "2.7.11.22", "activity": "", "evidence": [ { "id": "E1BB52", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BB52" } ] } ] }, { "uniprot_ac": "E1BBM3", "gene_name": "NEK1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "E1BBM3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BBM3" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "E1BBM3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BBM3" } ] } ] }, { "uniprot_ac": "E1BC36", "gene_name": "CDK6", "activity": [ { "ec_number": "2.7.11.22", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "E1BC36", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BC36" } ] }, { "ec_number": "2.7.11.22", "activity": "", "evidence": [ { "id": "E1BC36", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BC36" } ] } ] }, { "uniprot_ac": "E1BC64", "gene_name": "LIMK1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "E1BC64", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BC64" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "E1BC64", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BC64" } ] } ] }, { "uniprot_ac": "E1BC69", "gene_name": "HIPK3", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "E1BC69", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BC69" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "E1BC69", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BC69" } ] } ] }, { "uniprot_ac": "E1BCC3", "gene_name": "UHMK1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "E1BCC3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BCC3" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "E1BCC3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BCC3" } ] } ] }, { "uniprot_ac": "E1BCH5", "gene_name": "LATS1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "E1BCH5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BCH5" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "E1BCH5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BCH5" } ] } ] }, { "uniprot_ac": "E1BCU9", "gene_name": "STK11", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "E1BCU9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BCU9" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "E1BCU9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BCU9" } ] } ] }, { "uniprot_ac": "E1BDG4", "gene_name": "MAK", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "E1BDG4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BDG4" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "E1BDG4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BDG4" } ] } ] }, { "uniprot_ac": "E1BEI6", "gene_name": "ATM", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "E1BEI6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BEI6" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "E1BEI6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BEI6" } ] } ] }, { "uniprot_ac": "E1BEW4", "gene_name": "LOC613515", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "E1BEW4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BEW4" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "E1BEW4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BEW4" } ] } ] }, { "uniprot_ac": "E1BFR5", "gene_name": "MASTL", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "E1BFR5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BFR5" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "E1BFR5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BFR5" } ] } ] }, { "uniprot_ac": "E1BFV2", "gene_name": "MAP3K21", "activity": [ { "ec_number": "2.7.11.25", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "E1BFV2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BFV2" } ] }, { "ec_number": "2.7.11.25", "activity": "", "evidence": [ { "id": "E1BFV2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BFV2" } ] } ] }, { "uniprot_ac": "E1BG90", "gene_name": "DYRK2", "activity": [ { "ec_number": "2.7.12.1", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "E1BG90", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BG90" } ] }, { "ec_number": "2.7.12.1", "activity": "", "evidence": [ { "id": "E1BG90", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BG90" } ] } ] }, { "uniprot_ac": "E1BGV8", "gene_name": "MAP3K19", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "E1BGV8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BGV8" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "E1BGV8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BGV8" } ] } ] }, { "uniprot_ac": "E1BH31", "gene_name": "MAP4K1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "E1BH31", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BH31" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "E1BH31", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BH31" } ] } ] }, { "uniprot_ac": "E1BHE1", "gene_name": "TAOK3", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "E1BHE1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BHE1" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "E1BHE1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BHE1" } ] } ] }, { "uniprot_ac": "E1BI01", "gene_name": "MAP2K5", "activity": [ { "ec_number": "2.7.12.2", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "E1BI01", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BI01" } ] }, { "ec_number": "2.7.12.2", "activity": "", "evidence": [ { "id": "E1BI01", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BI01" } ] } ] }, { "uniprot_ac": "E1BI47", "gene_name": "PLK5", "activity": [ { "ec_number": "2.7.11.21", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "E1BI47", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BI47" } ] }, { "ec_number": "2.7.11.21", "activity": "", "evidence": [ { "id": "E1BI47", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BI47" } ] } ] }, { "uniprot_ac": "E1BJ19", "gene_name": "TAOK1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "E1BJ19", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BJ19" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "E1BJ19", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BJ19" } ] } ] }, { "uniprot_ac": "E1BJH5", "gene_name": "MAP4K3", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "E1BJH5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BJH5" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "E1BJH5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BJH5" } ] } ] }, { "uniprot_ac": "E1BJM5", "gene_name": "MTERF4", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "E1BJM5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BJM5" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "E1BJM5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BJM5" } ] } ] }, { "uniprot_ac": "E1BK33", "gene_name": "MAST1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "E1BK33", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BK33" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "E1BK33", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BK33" } ] } ] }, { "uniprot_ac": "E1BK52", "gene_name": "STK10", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "E1BK52", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BK52" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "E1BK52", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BK52" } ] } ] }, { "uniprot_ac": "E1BKX9", "gene_name": "CDKL5", "activity": [ { "ec_number": "2.7.11.22", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "E1BKX9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BKX9" } ] }, { "ec_number": "2.7.11.22", "activity": "", "evidence": [ { "id": "E1BKX9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BKX9" } ] } ] }, { "uniprot_ac": "E1BL08", "gene_name": "MAP3K14", "activity": [ { "ec_number": "2.7.11.25", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "E1BL08", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BL08" } ] }, { "ec_number": "2.7.11.25", "activity": "", "evidence": [ { "id": "E1BL08", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BL08" } ] } ] }, { "uniprot_ac": "E1BLQ5", "gene_name": "RPS6KB2", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "E1BLQ5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BLQ5" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "E1BLQ5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BLQ5" } ] } ] }, { "uniprot_ac": "E1BM19", "gene_name": "CDKL3", "activity": [ { "ec_number": "2.7.11.22", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "E1BM19", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BM19" } ] }, { "ec_number": "2.7.11.22", "activity": "", "evidence": [ { "id": "E1BM19", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BM19" } ] } ] }, { "uniprot_ac": "E1BMN8", "gene_name": "NLK", "activity": [ { "ec_number": "2.7.11.24", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "E1BMN8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BMN8" } ] }, { "ec_number": "2.7.11.24", "activity": "", "evidence": [ { "id": "E1BMN8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BMN8" } ] } ] }, { "uniprot_ac": "E1BN63", "gene_name": "WNK1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "E1BN63", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BN63" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "E1BN63", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BN63" } ] } ] }, { "uniprot_ac": "E1BN72", "gene_name": "NIM1K", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "E1BN72", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BN72" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "E1BN72", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BN72" } ] } ] }, { "uniprot_ac": "E1BNH0", "gene_name": "WNK2", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "E1BNH0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BNH0" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "E1BNH0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BNH0" } ] } ] }, { "uniprot_ac": "E1BNS8", "gene_name": "SIK1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "E1BNS8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BNS8" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "E1BNS8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BNS8" } ] } ] }, { "uniprot_ac": "E1BP01", "gene_name": "MYO3A", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "E1BP01", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BP01" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "E1BP01", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BP01" } ] } ] }, { "uniprot_ac": "E1BP72", "gene_name": "CDC42BPB", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "E1BP72", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BP72" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "E1BP72", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BP72" } ] } ] }, { "uniprot_ac": "E1BPB5", "gene_name": "TESK1", "activity": [ { "ec_number": "2.7.12.1", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "E1BPB5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BPB5" } ] }, { "ec_number": "2.7.12.1", "activity": "", "evidence": [ { "id": "E1BPB5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BPB5" } ] } ] }, { "uniprot_ac": "E1BPP1", "gene_name": "TTK", "activity": [ { "ec_number": "2.7.12.1", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "E1BPP1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BPP1" } ] }, { "ec_number": "2.7.12.1", "activity": "", "evidence": [ { "id": "E1BPP1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BPP1" } ] } ] }, { "uniprot_ac": "E1BPU0", "gene_name": "LRRK2", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "E1BPU0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BPU0" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "E1BPU0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BPU0" } ] } ] }, { "uniprot_ac": "E1BQ34", "gene_name": "HIPK1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "E1BQ34", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BQ34" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "E1BQ34", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BQ34" } ] } ] }, { "uniprot_ac": "F1MAZ8", "gene_name": "MARK3", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "F1MAZ8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MAZ8" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "F1MAZ8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MAZ8" } ] } ] }, { "uniprot_ac": "F1MBN7", "gene_name": "RIOK2", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "F1MBN7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MBN7" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "F1MBN7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MBN7" } ] } ] }, { "uniprot_ac": "F1MC27", "gene_name": "LMTK3", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "F1MC27", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MC27" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "F1MC27", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MC27" } ] } ] }, { "uniprot_ac": "F1MC61", "gene_name": "MAP3K11", "activity": [ { "ec_number": "2.7.11.25", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "F1MC61", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MC61" } ] }, { "ec_number": "2.7.11.25", "activity": "", "evidence": [ { "id": "F1MC61", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MC61" } ] } ] }, { "uniprot_ac": "F1MDC9", "gene_name": "PRKCE", "activity": [ { "ec_number": "2.7.11.13", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "F1MDC9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MDC9" } ] }, { "ec_number": "2.7.11.13", "activity": "", "evidence": [ { "id": "F1MDC9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MDC9" } ] } ] }, { "uniprot_ac": "F1MDS3", "gene_name": "PCK2", "activity": [ { "ec_number": "4.1.1.32", "activity": "ITP + oxaloacetate = IDP + phosphoenolpyruvate + CO2.", "evidence": [ { "id": "F1MDS3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MDS3" } ] }, { "ec_number": "4.1.1.32", "activity": "", "evidence": [ { "id": "F1MDS3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MDS3" } ] } ] }, { "uniprot_ac": "F1MF36", "gene_name": "KSR2", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "F1MF36", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MF36" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "F1MF36", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MF36" } ] } ] }, { "uniprot_ac": "F1MF50", "gene_name": "ROCK1", "activity": [ { "ec_number": "2.7.11.39", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "F1MF50", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MF50" } ] }, { "ec_number": "2.7.11.39", "activity": "", "evidence": [ { "id": "F1MF50", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MF50" } ] } ] }, { "uniprot_ac": "F1MFK1", "gene_name": "PKN2", "activity": [ { "ec_number": "2.7.11.13", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "F1MFK1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MFK1" } ] }, { "ec_number": "2.7.11.13", "activity": "", "evidence": [ { "id": "F1MFK1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MFK1" } ] } ] }, { "uniprot_ac": "F1MG29", "gene_name": "TSSK3", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "F1MG29", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MG29" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "F1MG29", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MG29" } ] } ] }, { "uniprot_ac": "F1MG35", "gene_name": "CIITA", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "F1MG35", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MG35" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "F1MG35", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MG35" } ] } ] }, { "uniprot_ac": "F1MG77", "gene_name": "HASPIN", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "F1MG77", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MG77" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "F1MG77", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MG77" } ] } ] }, { "uniprot_ac": "F1MGX2", "gene_name": "MAP3K13", "activity": [ { "ec_number": "2.7.11.25", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "F1MGX2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MGX2" } ] }, { "ec_number": "2.7.11.25", "activity": "", "evidence": [ { "id": "F1MGX2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MGX2" } ] } ] }, { "uniprot_ac": "F1MH23", "gene_name": "MAPKAPK5", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "F1MH23", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MH23" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "F1MH23", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MH23" } ] } ] }, { "uniprot_ac": "F1MH24", "gene_name": "AAK1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "F1MH24", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MH24" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "F1MH24", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MH24" } ] } ] }, { "uniprot_ac": "F1MH45", "gene_name": "CDC42BPA", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "F1MH45", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MH45" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "F1MH45", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MH45" } ] } ] }, { "uniprot_ac": "F1MI60", "gene_name": "MAP4K4", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "F1MI60", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MI60" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "F1MI60", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MI60" } ] } ] }, { "uniprot_ac": "F1MIB2", "gene_name": "GAK", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "F1MIB2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MIB2" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "F1MIB2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MIB2" } ] } ] }, { "uniprot_ac": "F1MJ55", "gene_name": "CSNK2A2", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "F1MJ55", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MJ55" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "F1MJ55", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MJ55" } ] } ] }, { "uniprot_ac": "F1MKK7", "gene_name": "PKMYT1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "F1MKK7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MKK7" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "F1MKK7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MKK7" } ] } ] }, { "uniprot_ac": "F1MKW8", "gene_name": "SIK2", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "F1MKW8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MKW8" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "F1MKW8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MKW8" } ] } ] }, { "uniprot_ac": "F1MKY9", "gene_name": "ALPK2", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "F1MKY9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MKY9" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "F1MKY9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MKY9" } ] } ] }, { "uniprot_ac": "F1MLY7", "gene_name": "ATR", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "F1MLY7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MLY7" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "F1MLY7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MLY7" } ] } ] }, { "uniprot_ac": "F1MM88", "gene_name": "NEK9", "activity": [ { "ec_number": "2.7.11.38", "activity": "L-threonyl-[protein] + ATP = O-phospho-L-threonyl-[protein] + ADP + H(+).", "evidence": [ { "id": "F1MM88", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MM88" } ] }, { "ec_number": "2.7.11.38", "activity": "", "evidence": [ { "id": "F1MM88", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MM88" } ] } ] }, { "uniprot_ac": "F1MN35", "gene_name": "PDIK1L", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "F1MN35", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MN35" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "F1MN35", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MN35" } ] } ] }, { "uniprot_ac": "F1MNP4", "gene_name": "RPS6KB1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "F1MNP4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MNP4" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "F1MNP4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MNP4" } ] } ] }, { "uniprot_ac": "F1MPF0", "gene_name": "TRPM7", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "F1MPF0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MPF0" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "F1MPF0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MPF0" } ] } ] }, { "uniprot_ac": "F1MPI8", "gene_name": "CDK8", "activity": [ { "ec_number": "2.7.11.22", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "F1MPI8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MPI8" } ] }, { "ec_number": "2.7.11.23", "activity": "[DNA-directed RNA polymerase] + ATP = phospho-[DNA-directed RNA polymerase] + ADP + H(+).", "evidence": [ { "id": "F1MPI8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MPI8" } ] }, { "ec_number": "2.7.11.22", "activity": "", "evidence": [ { "id": "F1MPI8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MPI8" } ] }, { "ec_number": "2.7.11.23", "activity": "", "evidence": [ { "id": "F1MPI8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MPI8" } ] } ] }, { "uniprot_ac": "F1MQ96", "gene_name": "PRKCI", "activity": [ { "ec_number": "2.7.11.13", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "F1MQ96", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MQ96" } ] }, { "ec_number": "2.7.11.13", "activity": "", "evidence": [ { "id": "F1MQ96", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MQ96" } ] } ] }, { "uniprot_ac": "F1MSI1", "gene_name": "STK17B", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "F1MSI1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MSI1" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "F1MSI1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MSI1" } ] } ] }, { "uniprot_ac": "F1MSV4", "gene_name": "SGK3", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "F1MSV4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MSV4" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "F1MSV4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MSV4" } ] } ] }, { "uniprot_ac": "F1MSX4", "gene_name": "MAP3K2", "activity": [ { "ec_number": "2.7.11.25", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "F1MSX4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MSX4" } ] }, { "ec_number": "2.7.11.25", "activity": "", "evidence": [ { "id": "F1MSX4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MSX4" } ] } ] }, { "uniprot_ac": "F1MU35", "gene_name": "PRKCG", "activity": [ { "ec_number": "2.7.11.13", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "F1MU35", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MU35" } ] }, { "ec_number": "2.7.11.13", "activity": "", "evidence": [ { "id": "F1MU35", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MU35" } ] } ] }, { "uniprot_ac": "F1MUU2", "gene_name": "STK35", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "F1MUU2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MUU2" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "F1MUU2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MUU2" } ] } ] }, { "uniprot_ac": "F1MVR0", "gene_name": "CDK19", "activity": [ { "ec_number": "2.7.11.22", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "F1MVR0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MVR0" } ] }, { "ec_number": "2.7.11.22", "activity": "", "evidence": [ { "id": "F1MVR0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MVR0" } ] } ] }, { "uniprot_ac": "F1MVV5", "gene_name": "MAPK4", "activity": [ { "ec_number": "2.7.11.24", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "F1MVV5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MVV5" } ] }, { "ec_number": "2.7.11.24", "activity": "", "evidence": [ { "id": "F1MVV5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MVV5" } ] } ] }, { "uniprot_ac": "F1MWN0", "gene_name": "EIF2AK1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "F1MWN0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MWN0" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "F1MWN0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MWN0" } ] } ] }, { "uniprot_ac": "F1MWP1", "gene_name": "BUB1B", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "F1MWP1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MWP1" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "F1MWP1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MWP1" } ] } ] }, { "uniprot_ac": "F1MXH6", "gene_name": "MAP3K5", "activity": [ { "ec_number": "2.7.11.25", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "F1MXH6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MXH6" } ] }, { "ec_number": "2.7.11.25", "activity": "", "evidence": [ { "id": "F1MXH6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MXH6" } ] } ] }, { "uniprot_ac": "F1MY55", "gene_name": "PAK5", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "F1MY55", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MY55" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "F1MY55", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MY55" } ] } ] }, { "uniprot_ac": "F1MY82", "gene_name": "PRKCH", "activity": [ { "ec_number": "2.7.11.13", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "F1MY82", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MY82" } ] }, { "ec_number": "2.7.11.13", "activity": "", "evidence": [ { "id": "F1MY82", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MY82" } ] } ] }, { "uniprot_ac": "F1MY86", "gene_name": "AURKC", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "F1MY86", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MY86" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "F1MY86", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MY86" } ] } ] }, { "uniprot_ac": "F1MYG2", "gene_name": "TLK1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "F1MYG2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MYG2" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "F1MYG2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MYG2" } ] } ] }, { "uniprot_ac": "F1MYM3", "gene_name": "PIK3CB", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "F1MYM3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MYM3" } ] }, { "ec_number": "2.7.1.153", "activity": "a 1,2-diacyl-sn-glycero-3-phospho-(1D-myo-inositol-4,5-bisphosphate) + ATP = a 1,2-diacyl-sn-glycero-3-phospho-(1D-myo-inositol-3,4,5-trisphosphate) + ADP + H(+).", "evidence": [ { "id": "F1MYM3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MYM3" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "F1MYM3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MYM3" } ] }, { "ec_number": "2.7.1.153", "activity": "", "evidence": [ { "id": "F1MYM3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MYM3" } ] } ] }, { "uniprot_ac": "F1MYV9", "gene_name": "OXSR1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "F1MYV9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MYV9" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "F1MYV9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MYV9" } ] } ] }, { "uniprot_ac": "F1N063", "gene_name": "CAMK1D", "activity": [ { "ec_number": "2.7.11.17", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "F1N063", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1N063" } ] }, { "ec_number": "2.7.11.17", "activity": "", "evidence": [ { "id": "F1N063", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1N063" } ] } ] }, { "uniprot_ac": "F1N2S7", "gene_name": "TSSK6", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "F1N2S7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1N2S7" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "F1N2S7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1N2S7" } ] } ] }, { "uniprot_ac": "F1N332", "gene_name": "ULK3", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "F1N332", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1N332" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "F1N332", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1N332" } ] } ] }, { "uniprot_ac": "F1N3W6", "gene_name": "MAP3K15", "activity": [ { "ec_number": "2.7.11.25", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "F1N3W6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1N3W6" } ] }, { "ec_number": "2.7.11.25", "activity": "", "evidence": [ { "id": "F1N3W6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1N3W6" } ] } ] }, { "uniprot_ac": "F1N5K1", "gene_name": "CDK11B", "activity": [ { "ec_number": "2.7.11.22", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "F1N5K1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1N5K1" } ] }, { "ec_number": "2.7.11.23", "activity": "[DNA-directed RNA polymerase] + ATP = phospho-[DNA-directed RNA polymerase] + ADP + H(+).", "evidence": [ { "id": "F1N5K1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1N5K1" } ] }, { "ec_number": "2.7.11.23", "activity": "", "evidence": [ { "id": "F1N5K1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1N5K1" } ] }, { "ec_number": "2.7.11.22", "activity": "", "evidence": [ { "id": "F1N5K1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1N5K1" } ] } ] }, { "uniprot_ac": "F1N5U0", "gene_name": "ALPK3", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "F1N5U0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1N5U0" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "F1N5U0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1N5U0" } ] } ] }, { "uniprot_ac": "F1N664", "gene_name": "MAP2K7", "activity": [ { "ec_number": "2.7.12.2", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "F1N664", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1N664" } ] }, { "ec_number": "2.7.12.2", "activity": "", "evidence": [ { "id": "F1N664", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1N664" } ] } ] }, { "uniprot_ac": "F1N6C1", "gene_name": "LRRK1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "F1N6C1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1N6C1" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "F1N6C1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1N6C1" } ] } ] }, { "uniprot_ac": "F6PN06", "gene_name": "TNK2", "activity": [ { "ec_number": "2.7.10.2", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "F6PN06", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F6PN06" } ] }, { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "F6PN06", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F6PN06" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "F6PN06", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F6PN06" } ] }, { "ec_number": "2.7.10.2", "activity": "", "evidence": [ { "id": "F6PN06", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F6PN06" } ] } ] }, { "uniprot_ac": "F6Q5B6", "gene_name": "EIF2AK2", "activity": [ { "ec_number": "2.7.10.2", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "F6Q5B6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F6Q5B6" } ] }, { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "F6Q5B6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F6Q5B6" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "F6Q5B6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F6Q5B6" } ] }, { "ec_number": "2.7.10.2", "activity": "", "evidence": [ { "id": "F6Q5B6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F6Q5B6" } ] } ] }, { "uniprot_ac": "F6Q5Z6", "gene_name": "BUB1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "F6Q5Z6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F6Q5Z6" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "F6Q5Z6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F6Q5Z6" } ] } ] }, { "uniprot_ac": "F6Q6K1", "gene_name": "CHEK1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "F6Q6K1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F6Q6K1" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "F6Q6K1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F6Q6K1" } ] } ] }, { "uniprot_ac": "F6Q9U9", "gene_name": "PNCK", "activity": [ { "ec_number": "2.7.11.17", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "F6Q9U9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F6Q9U9" } ] }, { "ec_number": "2.7.11.17", "activity": "", "evidence": [ { "id": "F6Q9U9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F6Q9U9" } ] } ] }, { "uniprot_ac": "F6QTX4", "gene_name": "RIPK3", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "F6QTX4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F6QTX4" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "F6QTX4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F6QTX4" } ] } ] }, { "uniprot_ac": "F6QVY2", "gene_name": "CDK20", "activity": [ { "ec_number": "2.7.11.22", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "F6QVY2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F6QVY2" } ] }, { "ec_number": "2.7.11.22", "activity": "", "evidence": [ { "id": "F6QVY2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F6QVY2" } ] } ] }, { "uniprot_ac": "F6QY93", "gene_name": "CDK3", "activity": [ { "ec_number": "2.7.11.22", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "F6QY93", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F6QY93" } ] }, { "ec_number": "2.7.11.22", "activity": "", "evidence": [ { "id": "F6QY93", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F6QY93" } ] } ] }, { "uniprot_ac": "F6RD87", "gene_name": "SRPK3", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "F6RD87", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F6RD87" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "F6RD87", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F6RD87" } ] } ] }, { "uniprot_ac": "F6RG88", "gene_name": "NEK4", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "F6RG88", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F6RG88" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "F6RG88", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F6RG88" } ] } ] }, { "uniprot_ac": "F6RLA2", "gene_name": "TSSK4", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "F6RLA2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F6RLA2" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "F6RLA2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F6RLA2" } ] } ] }, { "uniprot_ac": "F6RP02", "gene_name": "PIM2", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "F6RP02", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F6RP02" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "F6RP02", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F6RP02" } ] } ] }, { "uniprot_ac": "F6RPH3", "gene_name": "MAPK13", "activity": [ { "ec_number": "2.7.11.24", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "F6RPH3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F6RPH3" } ] }, { "ec_number": "2.7.11.24", "activity": "", "evidence": [ { "id": "F6RPH3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F6RPH3" } ] } ] }, { "uniprot_ac": "G3MX00", "gene_name": "", "activity": [ { "ec_number": "2.7.11.22", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "G3MX00", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3MX00" } ] }, { "ec_number": "2.7.11.22", "activity": "", "evidence": [ { "id": "G3MX00", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3MX00" } ] } ] }, { "uniprot_ac": "G3N022", "gene_name": "SPEG", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "G3N022", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3N022" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "G3N022", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3N022" } ] } ] }, { "uniprot_ac": "G3N2D2", "gene_name": "TSSK1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "G3N2D2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3N2D2" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "G3N2D2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3N2D2" } ] } ] }, { "uniprot_ac": "G3N2F6", "gene_name": "PIM3", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "G3N2F6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3N2F6" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "G3N2F6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3N2F6" } ] } ] }, { "uniprot_ac": "G3N2J4", "gene_name": "TTBK1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "G3N2J4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3N2J4" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "G3N2J4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3N2J4" } ] } ] }, { "uniprot_ac": "G5E518", "gene_name": "CDK12", "activity": [ { "ec_number": "2.7.11.22", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "G5E518", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G5E518" } ] }, { "ec_number": "2.7.11.23", "activity": "[DNA-directed RNA polymerase] + ATP = phospho-[DNA-directed RNA polymerase] + ADP + H(+).", "evidence": [ { "id": "G5E518", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G5E518" } ] }, { "ec_number": "2.7.11.22", "activity": "", "evidence": [ { "id": "G5E518", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G5E518" } ] }, { "ec_number": "2.7.11.23", "activity": "", "evidence": [ { "id": "G5E518", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G5E518" } ] } ] }, { "uniprot_ac": "G5E577", "gene_name": "MAPK6", "activity": [ { "ec_number": "2.7.11.24", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "G5E577", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G5E577" } ] }, { "ec_number": "2.7.11.24", "activity": "", "evidence": [ { "id": "G5E577", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G5E577" } ] } ] }, { "uniprot_ac": "G5E5A0", "gene_name": "STK17A", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "G5E5A0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G5E5A0" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "G5E5A0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G5E5A0" } ] } ] }, { "uniprot_ac": "G5E5D4", "gene_name": "MARK1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "G5E5D4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G5E5D4" } ] }, { "ec_number": "2.7.11.26", "activity": "L-seryl-[tau protein] + ATP = O-phospho-L-seryl-[tau protein] + ADP + H(+).", "evidence": [ { "id": "G5E5D4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G5E5D4" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "G5E5D4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G5E5D4" } ] }, { "ec_number": "2.7.11.26", "activity": "", "evidence": [ { "id": "G5E5D4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G5E5D4" } ] } ] }, { "uniprot_ac": "G5E5K2", "gene_name": "MASTL", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "G5E5K2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G5E5K2" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "G5E5K2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G5E5K2" } ] } ] }, { "uniprot_ac": "H2XJE8", "gene_name": "AAK1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "H2XJE8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/H2XJE8" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "H2XJE8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/H2XJE8" } ] } ] }, { "uniprot_ac": "H2XJE9", "gene_name": "NLK", "activity": [ { "ec_number": "2.7.11.24", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "H2XJE9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/H2XJE9" } ] }, { "ec_number": "2.7.11.24", "activity": "", "evidence": [ { "id": "H2XJE9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/H2XJE9" } ] } ] }, { "uniprot_ac": "P00516", "gene_name": "PRKG1", "activity": [ { "ec_number": "2.7.11.12", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "P00516", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P00516" } ] }, { "ec_number": "2.7.11.12", "activity": "", "evidence": [ { "id": "P00516", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P00516" } ] } ] }, { "uniprot_ac": "P00517", "gene_name": "PRKACA", "activity": [ { "ec_number": "2.7.11.11", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "P00517", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P00517" } ] }, { "ec_number": "2.7.11.11", "activity": "", "evidence": [ { "id": "P00517", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P00517" } ] } ] }, { "uniprot_ac": "P04409", "gene_name": "PRKCA", "activity": [ { "ec_number": "2.7.11.13", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "P04409", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P04409" } ] }, { "ec_number": "2.7.11.13", "activity": "", "evidence": [ { "id": "P04409", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P04409" } ] } ] }, { "uniprot_ac": "P05126", "gene_name": "PRKCB", "activity": [ { "ec_number": "2.7.11.13", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "P05126", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P05126" } ] }, { "ec_number": "2.7.11.13", "activity": "", "evidence": [ { "id": "P05126", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P05126" } ] } ] }, { "uniprot_ac": "P05128", "gene_name": "PRKCG", "activity": [ { "ec_number": "2.7.11.13", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "P05128", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P05128" } ] }, { "ec_number": "2.7.11.13", "activity": "", "evidence": [ { "id": "P05128", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P05128" } ] } ] }, { "uniprot_ac": "P05131", "gene_name": "PRKACB", "activity": [ { "ec_number": "2.7.11.11", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "P05131", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P05131" } ] }, { "ec_number": "2.7.11.11", "activity": "", "evidence": [ { "id": "P05131", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P05131" } ] } ] }, { "uniprot_ac": "P20427", "gene_name": "CSNK2A2", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "P20427", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P20427" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "P20427", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P20427" } ] } ] }, { "uniprot_ac": "P32871", "gene_name": "PIK3CA", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "P32871", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P32871" } ] }, { "ec_number": "2.7.1.153", "activity": "a 1,2-diacyl-sn-glycero-3-phospho-(1D-myo-inositol-4,5-bisphosphate) + ATP = a 1,2-diacyl-sn-glycero-3-phospho-(1D-myo-inositol-3,4,5-trisphosphate) + ADP + H(+).", "evidence": [ { "id": "P32871", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P32871" } ] }, { "ec_number": "2.7.1.137", "activity": "a 1,2-diacyl-sn-glycero-3-phospho-(1D-myo-inositol) + ATP = a 1,2-diacyl-sn-glycero-3-phospho-(1D-myo-inositol-3-phosphate) + ADP + H(+).", "evidence": [ { "id": "P32871", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P32871" } ] }, { "ec_number": "2.7.1.153", "activity": "", "evidence": [ { "id": "P32871", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P32871" } ] }, { "ec_number": "2.7.1.137", "activity": "", "evidence": [ { "id": "P32871", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P32871" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "P32871", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P32871" } ] } ] }, { "uniprot_ac": "P35507", "gene_name": "CSNK1B", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "P35507", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P35507" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "P35507", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P35507" } ] } ] }, { "uniprot_ac": "P35508", "gene_name": "CSNK1D", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "P35508", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P35508" } ] }, { "ec_number": "2.7.11.26", "activity": "L-seryl-[tau protein] + ATP = O-phospho-L-seryl-[tau protein] + ADP + H(+).", "evidence": [ { "id": "P35508", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P35508" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "P35508", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P35508" } ] } ] }, { "uniprot_ac": "P35509", "gene_name": "CSNK1G3", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "P35509", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P35509" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "P35509", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P35509" } ] } ] }, { "uniprot_ac": "P46196", "gene_name": "MAPK1", "activity": [ { "ec_number": "2.7.11.24", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "P46196", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P46196" } ] }, { "ec_number": "2.7.11.24", "activity": "", "evidence": [ { "id": "P46196", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P46196" } ] } ] }, { "uniprot_ac": "P48734", "gene_name": "CDK1", "activity": [ { "ec_number": "2.7.11.22", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "P48734", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P48734" } ] }, { "ec_number": "2.7.11.23", "activity": "[DNA-directed RNA polymerase] + ATP = phospho-[DNA-directed RNA polymerase] + ADP + H(+).", "evidence": [ { "id": "P48734", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P48734" } ] }, { "ec_number": "2.7.11.23", "activity": "", "evidence": [ { "id": "P48734", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P48734" } ] }, { "ec_number": "2.7.11.22", "activity": "", "evidence": [ { "id": "P48734", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P48734" } ] } ] }, { "uniprot_ac": "P52175", "gene_name": "NME1", "activity": [ { "ec_number": "3.1.11.-", "activity": "", "evidence": [ { "id": "P52175", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P52175" } ] }, { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "P52175", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P52175" } ] }, { "ec_number": "2.7.4.6", "activity": "UDP + ATP = UTP + ADP.", "evidence": [ { "id": "P52175", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P52175" } ] }, { "ec_number": "2.7.13.3", "activity": "ATP + protein L-histidine = ADP + protein N-phospho-L-histidine.", "evidence": [ { "id": "P52175", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P52175" } ] }, { "ec_number": "2.7.4.18", "activity": "(2E,6E)-farnesyl diphosphate + ATP = (2E,6E)-farnesyl triphosphate + ADP.", "evidence": [ { "id": "P52175", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P52175" } ] }, { "ec_number": "3.1.24.-", "activity": "", "evidence": [ { "id": "P52175", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P52175" } ] }, { "ec_number": "2.7.4.6", "activity": "", "evidence": [ { "id": "P52175", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P52175" } ] } ] }, { "uniprot_ac": "P67827", "gene_name": "CSNK1A1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "P67827", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P67827" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "P67827", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P67827" } ] } ] }, { "uniprot_ac": "P68399", "gene_name": "CSNK2A1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "P68399", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P68399" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "P68399", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P68399" } ] } ] }, { "uniprot_ac": "Q01314", "gene_name": "AKT1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "Q01314", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q01314" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "Q01314", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q01314" } ] } ] }, { "uniprot_ac": "Q02399", "gene_name": "CDK5", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "Q02399", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q02399" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "Q02399", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q02399" } ] } ] }, { "uniprot_ac": "Q08DZ2", "gene_name": "PRP4K", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "Q08DZ2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q08DZ2" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "Q08DZ2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q08DZ2" } ] } ] }, { "uniprot_ac": "Q08E52", "gene_name": "PAK1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "Q08E52", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q08E52" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "Q08E52", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q08E52" } ] } ] }, { "uniprot_ac": "Q0V7M1", "gene_name": "PSKH1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "Q0V7M1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q0V7M1" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "Q0V7M1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q0V7M1" } ] } ] }, { "uniprot_ac": "Q0VD22", "gene_name": "STK33", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "Q0VD22", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q0VD22" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "Q0VD22", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q0VD22" } ] } ] }, { "uniprot_ac": "Q17QV9", "gene_name": "STK40", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "Q17QV9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q17QV9" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "Q17QV9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q17QV9" } ] } ] }, { "uniprot_ac": "Q17R13", "gene_name": "TNK2", "activity": [ { "ec_number": "2.7.10.2", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "Q17R13", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q17R13" } ] }, { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "Q17R13", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q17R13" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "Q17R13", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q17R13" } ] }, { "ec_number": "2.7.10.2", "activity": "", "evidence": [ { "id": "Q17R13", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q17R13" } ] } ] }, { "uniprot_ac": "Q1RMT7", "gene_name": "RIOK3", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "Q1RMT7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q1RMT7" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "Q1RMT7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q1RMT7" } ] } ] }, { "uniprot_ac": "Q1RMT8", "gene_name": "IRAK4", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "Q1RMT8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q1RMT8" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "Q1RMT8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q1RMT8" } ] } ] }, { "uniprot_ac": "Q28021", "gene_name": "ROCK2", "activity": [ { "ec_number": "2.7.11.39", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "Q28021", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q28021" } ] }, { "ec_number": "2.7.11.39", "activity": "", "evidence": [ { "id": "Q28021", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q28021" } ] } ] }, { "uniprot_ac": "Q2HJF7", "gene_name": "CAMK2D", "activity": [ { "ec_number": "2.7.11.17", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "Q2HJF7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q2HJF7" } ] }, { "ec_number": "2.7.11.17", "activity": "", "evidence": [ { "id": "Q2HJF7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q2HJF7" } ] } ] }, { "uniprot_ac": "Q2KIP2", "gene_name": "HASPIN", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "Q2KIP2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q2KIP2" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "Q2KIP2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q2KIP2" } ] } ] }, { "uniprot_ac": "Q2KJG8", "gene_name": "BCKDK", "activity": [ { "ec_number": "2.7.11.-", "activity": "", "evidence": [ { "id": "Q2KJG8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q2KJG8" } ] }, { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "Q2KJG8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q2KJG8" } ] }, { "ec_number": "2.7.11.4", "activity": "L-seryl-[3-methyl-2-oxobutanoate dehydrogenase] + ATP = O-phospho-L-seryl-[3-methyl-2-oxobutanoate dehydrogenase] + ADP + H(+).", "evidence": [ { "id": "Q2KJG8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q2KJG8" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "Q2KJG8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q2KJG8" } ] } ] }, { "uniprot_ac": "Q2LGB3", "gene_name": "IRAK1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "Q2LGB3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q2LGB3" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "Q2LGB3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q2LGB3" } ] } ] }, { "uniprot_ac": "Q2TA06", "gene_name": "AURKA", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "Q2TA06", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q2TA06" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "Q2TA06", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q2TA06" } ] } ] }, { "uniprot_ac": "Q2TA25", "gene_name": "PLK1", "activity": [ { "ec_number": "2.7.11.21", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "Q2TA25", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q2TA25" } ] }, { "ec_number": "2.7.11.21", "activity": "", "evidence": [ { "id": "Q2TA25", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q2TA25" } ] } ] }, { "uniprot_ac": "Q2TBL8", "gene_name": "CDK10", "activity": [ { "ec_number": "2.7.11.22", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "Q2TBL8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q2TBL8" } ] }, { "ec_number": "2.7.11.22", "activity": "", "evidence": [ { "id": "Q2TBL8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q2TBL8" } ] } ] }, { "uniprot_ac": "Q2YDN8", "gene_name": "VRK3", "activity": [ { "ec_number": "2.7.11.22", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "Q2YDN8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q2YDN8" } ] }, { "ec_number": "2.7.11.22", "activity": "", "evidence": [ { "id": "Q2YDN8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q2YDN8" } ] } ] }, { "uniprot_ac": "Q32KY4", "gene_name": "CDK4", "activity": [ { "ec_number": "2.7.11.22", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "Q32KY4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q32KY4" } ] }, { "ec_number": "2.7.11.22", "activity": "", "evidence": [ { "id": "Q32KY4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q32KY4" } ] } ] }, { "uniprot_ac": "Q32L23", "gene_name": "LIMK2", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "Q32L23", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q32L23" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "Q32L23", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q32L23" } ] } ] }, { "uniprot_ac": "Q32PI1", "gene_name": "VRK1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = 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"MQGPRSEKVEILRLAQSKKNINSLNMDLERDMQRIDEANQDLLVKIHKKEDEIQRLENEITQTRDLAEDEELEKENTTTMERERALQEMEEETARLERKNETLVHSIAELERQLTRKSQKATKCEQDNLKGTPEESKVKLQQLEASCADQEKELAKVIEDYAFVAQLCEDQALCIKKYQETLKKIQEELETRFLEREVMKRKRPKLHKASN", "length": 211, "header": "tr|A0AAA9TNK1-1|F1N3R9_BOVIN Computationally mapped isoform of Transmembrane and coiled-coil domains 5A OS=Bos taurus OX=9913 GN=TMCO5A PE=4 SV=1 CANONICAL=F1N3R9-1" }, "locus": { "chromosome": "10", "start_pos": 33573611, "end_pos": 33566437, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000113376.2", "url": "https://www.ensembl.org/id/ENSBTAT00000113376.2" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000097924.1", "url": "https://www.ensembl.org/id/ENSBTAP00000097924.1" } ] } }, { "isoform_ac": "F1N3R9-1", "url": "https://www.uniprot.org/uniprotkb/F1N3R9/entry", "sequence": { "sequence": "MEEQKEDQLDYESEKVEILRLAQSKKNINSLNMDLERDMQRIDEANQDLLVKIHKKEDEIQRLENEITQTRDLAEDEELEKENTTTMERERALQEMEEETARLERKNETLVHSIAELERQLTRKSQKATKCEQDNLKGTPEESKVKLQQLEASCADQEKELAKVIEDYAFVAQLCEDQALCIKKYQETLKKIQEELETRFLEREVSKVMCMISTSKEYNSQNNKDNSLQKKKAGFCKRIFQYFFFTTLFLIRLLGYLLFHISFINPDLFVNILPRILSRNVLWKLRCFLFPSLTLETEDMLPH", "length": 303, "header": "tr|F1N3R9-1|F1N3R9_BOVIN Isoform 1 of Transmembrane and coiled-coil domains 5A OS=Bos taurus OX=9913 GN=TMCO5A PE=4 SV=2 CANONICAL=F1N3R9-1" }, "locus": { "chromosome": "10", "start_pos": 33580071, "end_pos": 33566374, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000038937.4", "url": "https://www.ensembl.org/id/ENSBTAT00000038937.4" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000038742.3", "url": "https://www.ensembl.org/id/ENSBTAP00000038742.3" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [ { "id": "bta:617536", "name": "", "url": 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sapiens", "sequence": { "sequence": "MEISRLAQSKRNIISLNMDLERDTQRIDEANQKLLLKIQEREDKIQRLESEIIQTRGLVEDEEWEKENRTTMERERALQELEEETARLERKNKTLVHSITELQQKLTRKSQKITNCEQSSPDGALEETKVKLQQLEASYACQEKELLKVMKEYAFVTQLCEDQALYIKKYQETLKKIEEELEALFLEREVSKLVSMNPVEKEHTSQNNEGTPTQKTARLFSKKIFCCLFFITLFFIRLLSYMFFHVRFINPDLLVNVLPKVLGRSTLWKLRCFFFPSLTLETEDMLPH", "length": 288 }, "evidence": [ { "id": "F1N3R9", "url": "https://omabrowser.org/oma/group/F1N3R9/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "Q9D9D5-1", "protein_name": "Transmembrane and coiled-coil domain-containing protein 5A", "gene_name": "Tmco5a", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MEILRLAQSKKNIISLNMDLERDMQRIDEANQELLLEIQEKENEIQRLEHEITQTGNPAEDEEWEKENYTVMEREQALQELEEETARLERKNETLVHSISELQRKLTRKSQKVIRYEQGDLETTPEESKVKLQQLESSCADQEKELGKIMEDYVFVSQLCEDQALCIKKYQEALKRIEEELETGYLEREVSKVLSMDSERERSTSLNKMDGFISKGALRFSKSIFRSLLFSTLFFIRLLGYLIFHLSFINPDLLVNALPKILSRDVLWKLRCFLFPSLTLETEDMLPH", "length": 288 }, "evidence": [ { "id": "F1N3R9", "url": "https://omabrowser.org/oma/group/F1N3R9/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" } ], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 2, "go_terms": [ { "name": "membrane", "id": "GO:0016020", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016020", "evidence": [ { "database": "UniProtKB", "id": "F1N3R9", "url": "https://www.uniprot.org/uniprotkb/F1N3R9" } ], "pmid": "" }, { "name": "plasma membrane", "id": "GO:0005886", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005886", "evidence": [ { "database": "UniProtKB", "id": "F1N3R9", "url": "https://www.uniprot.org/uniprotkb/F1N3R9" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 107, "end_pos": 109, "annotation": "n_glycosylation_sequon" }, { "start_pos": 83, "end_pos": 85, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [ { "pdb_id": "AF-F1N3R9-F1", "pdb_chain": "global", "start_pos": 1, "end_pos": 303, "overlap": "1.0", "method": "AlphaFold", "type": "alphafold", "resolution": -1.0, "url": "https://data.glygen.org/ln2downloads/pdb/current/AF-F1N3R9-F1.pdb", "url_external": "https://alphafold.ebi.ac.uk/entry/F1N3R9" } ], "lectin_list": [], "domain_list": [], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" }, { "name": "homologset.oma", "label": "OMA Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], 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"count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ], "tool_support": { "graph_view": "yes" } }, { "uniprot_canonical_ac": "F6PT99-1", "uniprot_ac": "F6PT99", "uniprot_id": "F6PT99_BOVIN", "mass": { "chemical_mass": 27450.0, "monoisotopic_mass": 27450.0 }, "refseq": {}, "gene_names": [ { "name": "CCDC28B", "type": "recommended", "evidence": [ { "id": "F6PT99", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F6PT99" } ] } ], "protein_names": [ { "name": "Coiled-coil domain containing 28B", "type": "synonym", "evidence": [ { "id": "F6PT99", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F6PT99/entry#names_and_taxonomy" } ] } ], "function": [], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Bos taurus", "taxid": 9913, "evidence": [ { "database": "UniProtKB", "id": "F6PT99", "url": "https://www.uniprot.org/uniprotkb/F6PT99" } ], "common_name": "Bovine", "glygen_name": "Bovine", "reference_species": "Bos taurus [9913]" } ], "gene": [ { "name": "CCDC28B", "url": "https://www.uniprot.org/uniprotkb/F6PT99", "locus": { "chromosome": "2", "start_pos": 121319787, "end_pos": 121324157, "strand": "+", "evidence": [ { "database": "Ensembl Gene", "id": "ENSBTAG00000015104", "url": "https://www.ensembl.org/id/ENSBTAG00000015104" } ] } } ], "crossref": [ { "id": "F6PT99", "url": "https://alphafold.ebi.ac.uk/entry/F6PT99", "database": "AlphaFoldDB", "categories": [] }, { "id": "ENSBTAG00000015104", "url": "https://bgee.org/?page=gene&gene_id=ENSBTAG00000015104", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "IPR025271", "url": "https://www.ebi.ac.uk/interpro/entry/IPR025271", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "QITYCEL", "url": 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"Protein" ] }, { "id": "F6PT99", "url": "https://www.uniprot.org/uniprotkb/F6PT99", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "F6PT99-1", "url": "https://www.uniprot.org/uniprotkb/F6PT99-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MQITYCELSFHPFLFPCWRELRAEGTRTEASLQTLNLQGLRPSQPPMEDKKKKRSPKPCLTQPAQPPGTLRRVPVPTSHSGSLALGLPHLPSPKQRTKFKRVGKEKCRPVLAGGAGGSAGTPLQHSFLTEVTDVYEMEGGLLNLLNDFHSGRLQAFGKECSFEQLEHVREMQEKLARLHFSLDVCGEEEDEEEEDDGVTDGLPEEQKKTMADRNLDQLLSNLEDLSNSIQKLHLAENAEPEEPSAV", "length": 246, "header": "tr|F6PT99-1|F6PT99_BOVIN Isoform 1 of Coiled-coil domain containing 28B OS=Bos taurus OX=9913 GN=CCDC28B PE=4 SV=2 CANONICAL=F6PT99-1" }, "isoforms": [ { "isoform_ac": "A0AAA9TPS8-1", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TPS8/entry", "sequence": { "sequence": "MQITYCELSFHPFLFPCWRELRAEGTRTEASLQTLNLQGLRPSQPPMEDKKKKRSPKPCLTQPAQPPGTLRRVPVPTSHSGSLALGLPHLPSPKQRTKFKRCVGKRPGGSQGSPSVMMHLRAGSEQTSRRVGKEKCRPVLAGGAGGSAGTPLQHSFLTEVTDVYEMEGGLLNLLNDFHSGRLQAFGKECSFEQLEHVREMQEKLARLHFSLDVCGEEEDEEEEDDGVTDGLPEEQKKTMADRNLDQLLSNLEDLSNSIQKLHLAENAEPEEPSAV", "length": 275, "header": "tr|A0AAA9TPS8-1|F6PT99_BOVIN Computationally mapped isoform of Coiled-coil domain containing 28B OS=Bos taurus OX=9913 GN=CCDC28B PE=4 SV=1 CANONICAL=F6PT99-1" }, "locus": { "chromosome": "2", "start_pos": 121323909, "end_pos": 121319925, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000109888.1", "url": "https://www.ensembl.org/id/ENSBTAT00000109888.1" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000100558.1", "url": "https://www.ensembl.org/id/ENSBTAP00000100558.1" } ] } }, { "isoform_ac": "F6PT99-1", "url": "https://www.uniprot.org/uniprotkb/F6PT99/entry", "sequence": { "sequence": "MQITYCELSFHPFLFPCWRELRAEGTRTEASLQTLNLQGLRPSQPPMEDKKKKRSPKPCLTQPAQPPGTLRRVPVPTSHSGSLALGLPHLPSPKQRTKFKRVGKEKCRPVLAGGAGGSAGTPLQHSFLTEVTDVYEMEGGLLNLLNDFHSGRLQAFGKECSFEQLEHVREMQEKLARLHFSLDVCGEEEDEEEEDDGVTDGLPEEQKKTMADRNLDQLLSNLEDLSNSIQKLHLAENAEPEEPSAV", "length": 246, "header": "tr|F6PT99-1|F6PT99_BOVIN Isoform 1 of Coiled-coil domain containing 28B OS=Bos taurus OX=9913 GN=CCDC28B PE=4 SV=2 CANONICAL=F6PT99-1" }, "locus": { "chromosome": "2", "start_pos": 121323909, "end_pos": 121319925, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000020099.6", "url": "https://www.ensembl.org/id/ENSBTAT00000020099.6" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000020099.5", "url": "https://www.ensembl.org/id/ENSBTAP00000020099.5" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [], "orthologs": [], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 1, "go_terms": [ { 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"total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ], "tool_support": { "graph_view": "yes" } }, { "uniprot_canonical_ac": "F1N498-1", "uniprot_ac": "F1N498", "uniprot_id": "F1N498_BOVIN", "mass": { "chemical_mass": 20822.0, "monoisotopic_mass": 20822.0 }, "refseq": {}, "gene_names": [ { "name": "MRPS11", "type": "recommended", "evidence": [ { "id": "F1N498", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1N498" } ] } ], "protein_names": [ { "name": "Small ribosomal subunit protein uS11m", "type": "recommended", "evidence": [ { "id": "F1N498", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1N498/entry#names_and_taxonomy" } ] }, { "name": "28S ribosomal protein S11, mitochondrial", "type": "synonym", "evidence": [ { "id": "F1N498", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1N498/entry#names_and_taxonomy" } ] } ], 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"https://www.ebi.ac.uk/interpro/entry/IPR001971", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR018102", "url": "https://www.ebi.ac.uk/interpro/entry/IPR018102", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR036967", "url": "https://www.ebi.ac.uk/interpro/entry/IPR036967", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "DNTPHPH", "url": "https://omabrowser.org/oma/group/DNTPHPH/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "F1N498", "url": "https://www.orthodb.org/?gene=F1N498", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR11759", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR11759", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00411", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00411", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "R-BTA-5389840", "url": "https://www.reactome.org/PathwayBrowser/#R-BTA-5389840", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "R-BTA-5419276", "url": "https://www.reactome.org/PathwayBrowser/#R-BTA-5419276", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "R-BTA-9937383", "url": "https://www.reactome.org/PathwayBrowser/#R-BTA-9937383", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "A0AAA9TQK3", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TQK3", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0AAA9TQK3-1", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TQK3-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "F1N498", "url": "https://www.uniprot.org/uniprotkb/F1N498", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "F1N498-1", "url": "https://www.uniprot.org/uniprotkb/F1N498-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], 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"-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000110931.2", "url": "https://www.ensembl.org/id/ENSBTAT00000110931.2" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000098698.1", "url": "https://www.ensembl.org/id/ENSBTAP00000098698.1" } ] } }, { "isoform_ac": "F1N498-1", "url": "https://www.uniprot.org/uniprotkb/F1N498/entry", "sequence": { "sequence": "MQVLRNAGSWLLRSWAWPPTTRVVAGVPAPTIHMSAQQMQDAAAKEEVEKAETPAPAPSRSSFSIYPPIPGQESSLRWAGKKFEEIPIAHIKASYNNTQIHVVSAAHQPLARASCGTEGFRNAKKGTGIAAQTAGIAAAAKATGKGVTHVRVVVKGLGPGRLSAIKGLTMGGLEVISITDNTPIPHNGCRPRKARRL", "length": 197, "header": "tr|F1N498-1|F1N498_BOVIN Isoform 1 of Small ribosomal subunit protein uS11m OS=Bos taurus OX=9913 GN=MRPS11 PE=3 SV=1 CANONICAL=F1N498-1" }, "locus": { "chromosome": "21", "start_pos": 19494853, "end_pos": 19484282, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000026421.5", "url": "https://www.ensembl.org/id/ENSBTAT00000026421.5" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000026421.3", "url": "https://www.ensembl.org/id/ENSBTAP00000026421.3" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [ { "id": "R-BTA-5389840", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-BTA-5389840", "resource": "Reactome", "description": "Mitochondrial translation elongation" }, { "id": "R-BTA-5419276", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-BTA-5419276", "resource": "Reactome", "description": "Mitochondrial translation termination" }, { "id": "R-BTA-9937383", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-BTA-9937383", "resource": "Reactome", "description": "Mitochondrial ribosome-associated quality control" } ], "orthologs": [ { "uniprot_canonical_ac": "A0A286ZJJ6-1", "protein_name": "Small ribosomal subunit protein uS11m", "gene_name": "MRPS11", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MQVVRNAGSRLLQSWAWPPKTRIVAGLPASTIHRSAPHLQDAAAKLDIEDKEEARTPSHSSFSIYPPIPGQENSLRWAGKKFEEIPIAHIKASYNNTQIQVVSAAHQPLAHASCGTEGFRNAKKGTGIAAQTAGIAAAAKATGKGVTHVRVVVKGLGPGRLSAIKGLTMGGLEVISITDNTPIPHNGCRPRKARRL", "length": 196 }, "evidence": [ { "id": "F1N498", "url": "https://omabrowser.org/oma/group/F1N498/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "G3IHZ9-1", "protein_name": "Small ribosomal subunit protein uS11m", "gene_name": "Mrps11", "tax_id": 10029, "organism": "Cricetulus griseus", "sequence": { "sequence": "MQVVRNTGAWLLRSWSGPGLTRLVAIAPAQTIHTGVPRLEDAAAKQEVEKQAAPSRFSIYPPAPGQESSLRWAGMRFEEVPVAHIKATHNNTQIQVVSAANVPLARASCGTEGFRNAKKGTGIAAQTAGIAAAAKATGKGVTHIRVVVKGMGPGRWSAIKGLTMGGLEVISVTDNTPVPHNGCRPRKARRL", "length": 191 }, "evidence": [ { "id": "F1N498", "url": "https://omabrowser.org/oma/group/F1N498/", "database": "OMA" } ], "glygen_name": "Hamster", "common_name": "Chinese hamster" }, { "uniprot_canonical_ac": "P82912-1", "protein_name": "Small ribosomal subunit protein uS11m", "gene_name": "MRPS11", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MQAVRNAGSRFLRSWTWPQTAGRVVARTPAGTICTGARQLQDAAAKQKVEQNAAPSHTKFSIYPPIPGEESSLRWAGKKFEEIPIAHIKASHNNTQIQVVSASNEPLAFASCGTEGFRNAKKGTGIAAQTAGIAAAARAKQKGVIHIRVVVKGLGPGRLSAMHGLIMGGLEVISITDNTPIPHNGCRPRKARKL", "length": 194 }, "evidence": [ { "id": "F1N498", "url": "https://omabrowser.org/oma/group/F1N498/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" } ], "go_annotation": { "categories": [ { "name": "Biological Process", "total": 1, "go_terms": [ { "name": "translation", "id": "GO:0006412", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006412", "evidence": [ { "database": "UniProtKB", "id": "F1N498", "url": "https://www.uniprot.org/uniprotkb/F1N498" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 4, "go_terms": [ { "name": "ribosome", "id": "GO:0005840", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005840", "evidence": [ { "database": "UniProtKB", "id": "F1N498", "url": "https://www.uniprot.org/uniprotkb/F1N498" } ], "pmid": "" }, { "name": "ribonucleoprotein complex", "id": "GO:1990904", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:1990904", "evidence": [ { "database": "UniProtKB", "id": "F1N498", "url": "https://www.uniprot.org/uniprotkb/F1N498" } ], "pmid": "" }, { "name": "mitochondrial small ribosomal subunit", "id": "GO:0005763", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005763", "evidence": [ { "database": "UniProtKB", "id": "F1N498", "url": "https://www.uniprot.org/uniprotkb/F1N498" } ], "pmid": "" }, { "name": "mitochondrial inner membrane", "id": "GO:0005743", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005743", "evidence": [ { "database": "UniProtKB", "id": "F1N498", "url": "https://www.uniprot.org/uniprotkb/F1N498" } ], "pmid": "" } ] }, { "name": "Molecular Function", "total": 1, "go_terms": [ { "name": "structural constituent of ribosome", "id": "GO:0003735", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003735", "evidence": [ { "database": "UniProtKB", "id": "F1N498", "url": "https://www.uniprot.org/uniprotkb/F1N498" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 96, "end_pos": 98, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [ { "pdb_id": "AF-F1N498-F1", "pdb_chain": "global", "start_pos": 1, "end_pos": 197, "overlap": "1.0", "method": "AlphaFold", "type": "alphafold", "resolution": -1.0, "url": "https://data.glygen.org/ln2downloads/pdb/current/AF-F1N498-F1.pdb", "url_external": "https://alphafold.ebi.ac.uk/entry/F1N498" } ], "lectin_list": [], "domain_list": [], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" }, { "name": "homologset.oma", "label": "OMA Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 96, "end_pos": 98 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ], "tool_support": { "graph_view": "yes" } }, { "uniprot_canonical_ac": "F1N3H2-1", "uniprot_ac": "F1N3H2", "uniprot_id": "F1N3H2_BOVIN", "mass": { "chemical_mass": 64906.0, "monoisotopic_mass": 64906.0 }, "refseq": { "ac": "XP_005209122", "name": "leucine-rich repeat and immunoglobulin-like domain-containing nogo receptor-interacting protein 3", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_005209122" }, "gene_names": [ { "name": "LINGO3", "type": "recommended", "evidence": [ { "id": "F1N3H2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1N3H2" } ] }, { "name": "LINGO3", "type": "synonym", "evidence": [ { "id": "XP_005209122", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_005209122" } ] } ], "protein_names": [ { "name": "Leucine rich repeat and Ig domain containing 3", "type": "synonym", "evidence": [ { "id": "F1N3H2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1N3H2/entry#names_and_taxonomy" } ] }, { "name": "leucine-rich repeat and immunoglobulin-like domain-containing nogo receptor-interacting protein 3", "type": "synonym", "evidence": [ { "id": "XP_005209122", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_005209122" } ] } ], "function": [], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Bos taurus", "taxid": 9913, "evidence": [ { "database": "UniProtKB", "id": "F1N3H2", "url": "https://www.uniprot.org/uniprotkb/F1N3H2" } ], "common_name": "Bovine", "glygen_name": "Bovine", "reference_species": "Bos taurus [9913]" } ], "gene": [ { "name": "LINGO3", "url": "https://www.uniprot.org/uniprotkb/F1N3H2", "locus": { "chromosome": "7", "start_pos": 21269837, "end_pos": 21253515, "strand": "-", "evidence": [ { "database": "Ensembl Gene", "id": "ENSBTAG00000016478", "url": "https://www.ensembl.org/id/ENSBTAG00000016478" } ] } } ], "crossref": [ { "id": "ENSBTAG00000016478", "url": "https://bgee.org/?page=gene&gene_id=ENSBTAG00000016478", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "618425", "url": "https://www.ncbi.nlm.nih.gov/gene/618425", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR000372", "url": "https://www.ebi.ac.uk/interpro/entry/IPR000372", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR000483", "url": "https://www.ebi.ac.uk/interpro/entry/IPR000483", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR001611", "url": "https://www.ebi.ac.uk/interpro/entry/IPR001611", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR003591", "url": "https://www.ebi.ac.uk/interpro/entry/IPR003591", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR003598", "url": "https://www.ebi.ac.uk/interpro/entry/IPR003598", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR003599", "url": "https://www.ebi.ac.uk/interpro/entry/IPR003599", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR007110", "url": "https://www.ebi.ac.uk/interpro/entry/IPR007110", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR013098", "url": "https://www.ebi.ac.uk/interpro/entry/IPR013098", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR013783", "url": "https://www.ebi.ac.uk/interpro/entry/IPR013783", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR032675", "url": "https://www.ebi.ac.uk/interpro/entry/IPR032675", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR036179", "url": "https://www.ebi.ac.uk/interpro/entry/IPR036179", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR050541", "url": "https://www.ebi.ac.uk/interpro/entry/IPR050541", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "bta:618425", "url": "https://www.genome.jp/dbget-bin/www_bget?bta:618425", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "KFTMKMI", "url": "https://omabrowser.org/oma/group/KFTMKMI/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "F1N3H2", "url": "https://www.orthodb.org/?gene=F1N3H2", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR24369", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR24369", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR24369:SF207", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR24369:SF207", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF01463", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF01463", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF07679", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF07679", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF13855", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF13855", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "XP_005209122", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_005209122", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0AAA9TR38", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TR38", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0AAA9TR38-1", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TR38-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "F1N3H2", "url": "https://www.uniprot.org/uniprotkb/F1N3H2", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "F1N3H2-1", "url": "https://www.uniprot.org/uniprotkb/F1N3H2-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MTCWLWVLSLQFLLLPAALPPAGGCPARCECTAQTRAVACPRRRLTAVPDGIPAETRLLELSRNRIRCLNPGDLAALPLLEELDLSENVIAHVEPGAFANLPRLRVLRLRGNLLKLIPPGVFTRLDNLTLLDLSENKLVILLDYTFQDLRSLRRLEVGDNDLVFISRRAFAGLLALEELTLERCNLTALSGESLGHLRGLGALRLRHLAIAALEDQNFQRLPGLLHLEIDNWPLLEEVAAGSLRGLNLTSLSVTHTNITAVPSAALRHQAHLTCLNLSHNPISTVPRGSFRDLVRLRELHLAGALLAVVEPQAFLGLRQIRLLNLSNNLLSTLEESTFHSVNTLETLRVDGNPLACDCRLLWVVQRRKTLNFDGRPPACATPAEVRGDALRSLPDSALFEYFVCRKPKIRERRLQRITAAAGADVRFQCRAEGEPAPTVAWVTPRHRTVTAASAGRARVLPGGTLHIQDARPGDSGTYTCVASNAGGNDTYFATLSVQPEPAVNRTPGEGRNDTQVAARFPLDLTTILVSTAMGCITFLGVVLFCFLLLFVWSRGRGQHKNNFSVEYSFRKVDGPAAAAGQGGARKFNMKMI", "length": 592, "header": "tr|F1N3H2-1|F1N3H2_BOVIN Isoform 1 of Leucine rich repeat and Ig domain containing 3 OS=Bos taurus OX=9913 GN=LINGO3 PE=4 SV=3 CANONICAL=F1N3H2-1" }, "isoforms": [ { "isoform_ac": "A0AAA9TR38-1", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TR38/entry", "sequence": { "sequence": "ETRLLELSRNRIRCLNPGDLAALPLLEELDLSENVIAHVEPGAFANLPRLRVLRLRGNLLKLIPPGVFTRLDNLTLLDLSENKLVILLDYTFQDLRSLRRLEVGDNDLVFISRRAFAGLLALEELTLERCNLTALSGESLGHLRGLGALRLRHLAIAALEDQNFQRLPGLLHLEIDNWPLLEEVAAGSLRGLNLTSLSVTHTNITAVPSAALRHQAHLTCLNLSHNPISTVPRGSFRDLVRLRELHLAGALLAVVEPQAFLGLRQIRLLNLSNNLLSTLEESTFHSVNTLETLRVDGNPLACDCRLLWVVQRRKTLNFDGRPPACATPAEVRGDALRSLPDSALFEYFVCRKPKIRERRLQRITAAAGADVRFQCRAEGEPAPTVAWVTPRHRTVTAASAGRARVLPGGTLHIQDARPGDSGTYTCVASNAGGNDTYFATLSVQPEPAVNRTPGEGRNDTQVAARFPLDLTTILVSTAMGCITFLGVVLFCFLLLFVWSRGRGQHKNNFSVEYSFRKVDGPAAAAGQGGARKFNMKMI", "length": 538, "header": "tr|A0AAA9TR38-1|F1N3H2_BOVIN Computationally mapped isoform of Leucine rich repeat and Ig domain containing 3 OS=Bos taurus OX=9913 GN=LINGO3 PE=4 SV=1 CANONICAL=F1N3H2-1" }, "locus": { "chromosome": "7", "start_pos": 21267394, "end_pos": 21265781, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000094884.1", "url": "https://www.ensembl.org/id/ENSBTAT00000094884.1" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000099481.1", "url": "https://www.ensembl.org/id/ENSBTAP00000099481.1" } ] } }, { "isoform_ac": "F1N3H2-1", "url": "https://www.uniprot.org/uniprotkb/F1N3H2/entry", "sequence": { "sequence": "MTCWLWVLSLQFLLLPAALPPAGGCPARCECTAQTRAVACPRRRLTAVPDGIPAETRLLELSRNRIRCLNPGDLAALPLLEELDLSENVIAHVEPGAFANLPRLRVLRLRGNLLKLIPPGVFTRLDNLTLLDLSENKLVILLDYTFQDLRSLRRLEVGDNDLVFISRRAFAGLLALEELTLERCNLTALSGESLGHLRGLGALRLRHLAIAALEDQNFQRLPGLLHLEIDNWPLLEEVAAGSLRGLNLTSLSVTHTNITAVPSAALRHQAHLTCLNLSHNPISTVPRGSFRDLVRLRELHLAGALLAVVEPQAFLGLRQIRLLNLSNNLLSTLEESTFHSVNTLETLRVDGNPLACDCRLLWVVQRRKTLNFDGRPPACATPAEVRGDALRSLPDSALFEYFVCRKPKIRERRLQRITAAAGADVRFQCRAEGEPAPTVAWVTPRHRTVTAASAGRARVLPGGTLHIQDARPGDSGTYTCVASNAGGNDTYFATLSVQPEPAVNRTPGEGRNDTQVAARFPLDLTTILVSTAMGCITFLGVVLFCFLLLFVWSRGRGQHKNNFSVEYSFRKVDGPAAAAGQGGARKFNMKMI", "length": 592, "header": "tr|F1N3H2-1|F1N3H2_BOVIN Isoform 1 of Leucine rich repeat and Ig domain containing 3 OS=Bos taurus OX=9913 GN=LINGO3 PE=4 SV=3 CANONICAL=F1N3H2-1" }, "locus": { "chromosome": "7", "start_pos": 21267394, "end_pos": 21265619, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000133220.1", "url": "https://www.ensembl.org/id/ENSBTAT00000133220.1" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000085072.1", "url": "https://www.ensembl.org/id/ENSBTAP00000085072.1" } ] } } ], "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "other", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 381, "start_aa": "Thr", "end_pos": 381, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr381", "evidence": [ { "id": "", "database": "GlyGen", "url": "https://data.glygen.org/" } ], "filter_code": "000000000000000010000.00000000001000.0.01000" }, { "glytoucan_ac": "", "type": "O-linked", "subtype": "other", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 438, "start_aa": "Thr", "end_pos": 438, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr438", "evidence": [ { "id": "", "database": "GlyGen", "url": "https://data.glygen.org/" } ], "filter_code": "000000000000000010000.00000000001000.0.01000" }, { "glytoucan_ac": "", "type": "O-linked", "subtype": "other", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 443, "start_aa": "Thr", "end_pos": 443, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr443", "evidence": [ { "id": "", "database": "GlyGen", "url": "https://data.glygen.org/" } ], "filter_code": "000000000000000010000.00000000001000.0.01000" } ], "phosphorylation": [], "glycation": [], "keywords": [ "glycoprotein", "glycoprotein_predicted" ], "publication": [], "pathway": [ { "id": "bta:618425", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?bta:618425", "resource": "KEGG Pathway" } ], "orthologs": [ { "uniprot_canonical_ac": "A0A1L1RQ93-1", "protein_name": "Leucine rich repeat and Ig domain containing 3", "gene_name": "LINGO3", "tax_id": 9031, "organism": "Gallus gallus", "sequence": { "sequence": "MLYTMTCWLPVLVLHLVLLSPLQVAACPARCECAPQIKSVVCHRKRLTAIPEGIPTETKILELNKNRIRCLNPGDLSPYPLLEELDFSENIITNVEPGAFSNLFNLQTLRLRGNQLKLIPPGVFTKLTNLTLLDISENKLVILLDYMFQDLRNLKSLEVGDNDLVYISQRAFSGLLGLEQLTIEKCNLTSISAESLSYLQNLEVLRLRHLSISALEEQNFKKLYNLLQLEIDNWPLLEDISPTSFQGLNLTSLSITYTNITAVPTAALRNLVYLRYLNLSYNPISTVLKGSFKDLIRLQELHIVGALLVSVEPQAFSGLRQIRLLNLSSNFLSTLEESTFHSVNTLETLRVDRNPLACDCRLLWILQRRKTLNFDGQQPMCSTPPEIQGNALRDFPDSVLFEYFTCQKPKIRDRKLQHVTAREGQSVSFLCRADGEPEPSIVWVSPQHRMITTRSTGRATVLPGGTLEIRFAQVQDSGTYICIASNAGGNDTYFATLTVKGHPNDGSSNANRTLYLNEFNDTYHNDTQVFLKFTLDLKTILVSTAMGCITFLGVVLFCFLLLFVWSRGRGQHKNNFSVEYSFRKVDGPTTTTGQGGARKFNMKMI", "length": 605 }, "evidence": [ { "id": "F1N3H2", "url": "https://omabrowser.org/oma/group/F1N3H2/", "database": "OMA" } ], "glygen_name": "Chicken", "common_name": "Chicken" }, { "uniprot_canonical_ac": "A0ABK0M4X1-1", "protein_name": "Leucine rich repeat and Ig domain containing 3", "gene_name": "Lingo3", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MTCWLHMLGLHLLLLPTAPLATGCPARCECSASTRTVACGRRRLTAVPEGIPAETRMLELSRNRIRCLNPGDLASLPTLEELDLNHNVIAHVEPGAFANLPRLRVLRLRGNQLKLIPPGVFTHLDSLTLLDLSENKLVILLDFSFQDLRSLQRLEVGDNDLVFISRRAFAGLLGLAELTLERCNLTSLSPESLGHLRGLGALRLRHLAIAALEDQNFQKLPGLLHLEIDNWPLLEEVAPGSLRGLNLTSLSITHTNITAVPAAALRQQAHLTCLNLSHNPISMVPRGSFRDLVRLRELHLAGALLAVIEPQAFVGLRQIRLLNLSDNLLSTLEENTFHSVNTLETLRVDGNPLACDCRLLWIVQRRKTLNFDGRLPACATPAEVRGDALHNLPDSVLFEYFVCRKPKIRERRLQHVTATEGDDVRFLCRAEGEPAPTVAWVTPQHHSVTAASRGRARVLPGGTLAITDTRPQDSGTYTCVASNAGGNDTYFATLTIHPAANRTQSDGHNETQVGVRFPLDLTTILVSTAMGCITFLGVVLFCFLLLFVWSRGRGQHKNNFSVEYSFRKVDGPAAAAGQGGARKFNMKMI", "length": 589 }, "evidence": [ { "id": "F1N3H2", "url": "https://omabrowser.org/oma/group/F1N3H2/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "F1S8I1-1", "protein_name": "Leucine rich repeat and Ig domain containing 3", "gene_name": "LINGO3", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MTCWLCVLSLQLLLLPAAPPPAGGCPARCECTAQTRAVACPRRRLTAVPDGIPAETRLLELSRNRIRCLNPGDLAALPLLEELDLSDNVIAHVEPGAFANLPRLRELRLRGNLLKLIPPGVFTRLDNLTLLDLSENKLVILLDYTFQDLRSLRRLEVGDNDLVFISRRAFAGLLALEELTLERCNLTALSGESLGHLRGLGALRLRHLAIAALEDQNFQRLPGLLHLEIDNWPLLEEVAAGSLRGLNLTSLSVTHTNITAVPAAALRHQAHLTCLNLSHNPISTVPRGSFRDLVRLRELHLAGALLAVVEPQAFLGLRQIRLLNLSNNLLSTLEESTFHSVNTLETLRVDGNPLACDCRLLWIVQRRKTLNFDGRLPACATPAEVRGDALRNLPDSVLFEYFVCRKPKIRERRLQHVTAAAGDDVRFQCRAEGEPAPTVAWVTPRHRAVTATSAGRARVLPGGTLQIRDAQPGDSGTYTCVASNAGGNDTYFATLSVQPEPATNRTLGEGRNDTQAAMRFPLDLTTILVSTAMGCITFLGVVLFCFLLLFVWSRGRGQHKNNFSVEYSFRKVDGPAAAAGQSGARKFNMKMI", "length": 592 }, "evidence": [ { "id": "F1N3H2", "url": "https://omabrowser.org/oma/group/F1N3H2/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "P0C6S8-1", "protein_name": "Leucine-rich repeat and immunoglobulin-like domain-containing nogo receptor-interacting protein 3", "gene_name": "LINGO3", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MTCWLCVLSLPLLLLPAAPPPAGGCPARCECTVQTRAVACTRRRLTAVPDGIPAETRLLELSRNRIRCLNPGDLAALPALEELDLSENAIAHVEPGAFANLPRLRVLRLRGNQLKLIPPGVFTRLDNLTLLDLSENKLVILLDYTFQDLHSLRRLEVGDNDLVFVSRRAFAGLLALEELTLERCNLTALSGESLGHLRSLGALRLRHLAIASLEDQNFRRLPGLLHLEIDNWPLLEEVAAGSLRGLNLTSLSVTHTNITAVPAAALRHQAHLTCLNLSHNPISTVPRGSFRDLVRLRELHLAGALLAVVEPQAFLGLRQIRLLNLSNNLLSTLEESTFHSVNTLETLRVDGNPLACDCRLLWIVQRRKTLNFDGRLPACATPAEVRGDALRNLPDSVLFEYFVCRKPKIRERRLQRVTATAGEDVRFLCRAEGEPAPTVAWVTPQHRPVTATSAGRARVLPGGTLEIQDARPQDSGTYTCVASNAGGNDTYFATLTVRPEPAANRTPGEAHNETLAALRAPLDLTTILVSTAMGCITFLGVVLFCFVLLFVWSRGRGQHKNNFSVEYSFRKVDGPAAAAGQGGARKFNMKMI", "length": 592 }, "evidence": [ { "id": "F1N3H2", "url": "https://omabrowser.org/oma/group/F1N3H2/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "Q6GQU6-1", "protein_name": "Leucine-rich repeat and immunoglobulin-like domain-containing nogo receptor-interacting protein 3", "gene_name": "Lingo3", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MTCWLHMLGLHLLLLPTAPLAAGCPARCECSASTRTVACGRRRLTAIPEGIPAETRMLELSRNRIRCLNPGDLASLPTLEELDLNHNVIAHVEPGAFANLPRLRVLRLRGNQLKLIPPGVFTHLDSLTLLDLSENKLVILLDFSFQDLRSLQRLEVGDNDLVFISRRAFAGLLGLAELTLERCNLTSLSPESLGHLRGLGALRLRHLAIAALEDQNFQKLPGLSHLEIDNWPLLEEVAPGSLRGLNLTSLSITHTNITAVPAAALRQQAHLTCLNLSHNPISMVPRGSFRDLVRLRELHLAGALLAVIEPQAFVGLRQIRLLNLSDNLLSTLEENTFHSVNTLETLRVDGNPLACDCRLLWIVQRRKTLNFDGRLPACATPAEVRGDALHNLPDSVLFEYFVCRKPKIRERRLQHVTATEGDDVRFLCRAEGEPAPTVAWVTPQHHSVTAASRGRARVLPGGTLTIADTRPQDSGTYTCVASNAGGNDTYFATLTVQPAANRTQGDGHNETQVGVRFPLDLTTILVSTAMGCITFLGVVLFCFLLLFVWSRGRGQHKNNFSVEYSFRKVDGPAAAAGQGGARKFNMKMI", "length": 589 }, "evidence": [ { "id": "F1N3H2", "url": "https://omabrowser.org/oma/group/F1N3H2/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" } ], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 2, "go_terms": [ { "name": "membrane", "id": "GO:0016020", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016020", "evidence": [ { "database": "UniProtKB", "id": "F1N3H2", "url": "https://www.uniprot.org/uniprotkb/F1N3H2" } ], "pmid": "" }, { "name": "plasma membrane", "id": "GO:0005886", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005886", "evidence": [ { "database": "UniProtKB", "id": "F1N3H2", "url": "https://www.uniprot.org/uniprotkb/F1N3H2" } ], "pmid": "" } ] }, { "name": "Molecular Function", "total": 1, "go_terms": [ { "name": "signaling receptor activity", "id": "GO:0038023", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0038023", "evidence": [ { "database": "UniProtKB", "id": "F1N3H2", "url": "https://www.uniprot.org/uniprotkb/F1N3H2" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 127, "end_pos": 129, "annotation": "n_glycosylation_sequon" }, { "start_pos": 185, "end_pos": 187, "annotation": "n_glycosylation_sequon" }, { "start_pos": 247, "end_pos": 249, "annotation": "n_glycosylation_sequon" }, { "start_pos": 257, "end_pos": 259, "annotation": "n_glycosylation_sequon" }, { "start_pos": 276, "end_pos": 278, "annotation": "n_glycosylation_sequon" }, { "start_pos": 324, "end_pos": 326, "annotation": "n_glycosylation_sequon" }, { "start_pos": 488, "end_pos": 490, "annotation": "n_glycosylation_sequon" }, { "start_pos": 504, "end_pos": 506, "annotation": "n_glycosylation_sequon" }, { "start_pos": 512, "end_pos": 514, "annotation": "n_glycosylation_sequon" }, { "start_pos": 562, "end_pos": 564, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "F1N3H2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1N3H2" }, { "id": "PS50835", "database": "PROSITE", "url": "https://prosite.expasy.org/PS50835" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "Ig-like", "eco_id": "ECO_0000259", "start_pos": 407, "end_pos": 496, "start_aa": "Pro", "end_aa": "Ser", "glycosite_overlap": [] } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" }, { "name": "homologset.oma", "label": "OMA Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [ 381, 438, 443 ], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 127, "end_pos": 129 }, { "start_pos": 185, "end_pos": 187 }, { "start_pos": 247, "end_pos": 249 }, { "start_pos": 257, "end_pos": 259 }, { "start_pos": 276, "end_pos": 278 }, { "start_pos": 324, "end_pos": 326 }, { "start_pos": 488, "end_pos": 490 }, { "start_pos": 504, "end_pos": 506 }, { "start_pos": 512, "end_pos": 514 }, { "start_pos": 562, "end_pos": 564 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 3 }, { "field": "total_sites", "count": 3 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 3 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "exact_sites", "count": 3 }, { "field": "exact_o_linked_sites", "count": 3 }, { "field": "fuzzy_sites", "count": 0 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_pos", "start_aa", "end_pos", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_reported", 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}, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ], "tool_support": { "graph_view": "yes" } }, { "uniprot_canonical_ac": "F1N349-1", "uniprot_ac": "F1N349", "uniprot_id": "F1N349_BOVIN", "mass": { "chemical_mass": 50737.0, "monoisotopic_mass": 50737.0 }, "refseq": { "ac": "NP_001289881", "name": "ankyrin repeat and SOCS box protein 18", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001289881" }, "gene_names": [ { "name": "ASB18", "type": "recommended", "evidence": [ { "id": "F1N349", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1N349" } ] }, { "name": "ASB18", "type": "synonym", "evidence": [ { "id": "NP_001289881", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001289881" } ] } ], "protein_names": [ { "name": "Ankyrin repeat and SOCS box containing 18", "type": "synonym", "evidence": [ { "id": "F1N349", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1N349/entry#names_and_taxonomy" } ] }, { "name": "ankyrin repeat and SOCS box protein 18", "type": "synonym", "evidence": [ { "id": "NP_001289881", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001289881" } ] } ], "function": [ { "annotation": "May be a substrate-recognition component of a SCF-like ECS (Elongin-Cullin-SOCS-box protein) E3 ubiquitin-protein ligase complex which mediates the ubiquitination and subsequent proteasomal degradation of target proteins.", "evidence": [ { "database": "UniProtKB", "id": "F1N349", "url": "https://www.uniprot.org/uniprotkb/F1N349#function" }, { "database": "UniProtKB", "id": "ARBA00003062", "url": "https://www.uniprot.org/uniprotkb/ARBA00003062#function" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Bos taurus", "taxid": 9913, "evidence": [ { "database": "UniProtKB", "id": "F1N349", "url": "https://www.uniprot.org/uniprotkb/F1N349" } ], "common_name": "Bovine", "glygen_name": "Bovine", "reference_species": "Bos taurus [9913]" } ], "gene": [ { "name": "ASB18", "url": "https://www.uniprot.org/uniprotkb/F1N349", "locus": { "chromosome": "3", "start_pos": 115663853, "end_pos": 115736014, "strand": "+", "evidence": [ { "database": "Ensembl Gene", "id": "ENSBTAG00000002024", "url": "https://www.ensembl.org/id/ENSBTAG00000002024" } ] } } ], "crossref": [ { "id": "F1N349", "url": "https://alphafold.ebi.ac.uk/entry/F1N349", "database": "AlphaFoldDB", "categories": [] }, { "id": "ENSBTAG00000002024", "url": "https://bgee.org/?page=gene&gene_id=ENSBTAG00000002024", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "cd03723", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd03723", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "100141009", "url": "https://www.ncbi.nlm.nih.gov/gene/100141009", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR001496", "url": "https://www.ebi.ac.uk/interpro/entry/IPR001496", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR002110", "url": "https://www.ebi.ac.uk/interpro/entry/IPR002110", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR036036", "url": "https://www.ebi.ac.uk/interpro/entry/IPR036036", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR036770", "url": "https://www.ebi.ac.uk/interpro/entry/IPR036770", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR051573", "url": "https://www.ebi.ac.uk/interpro/entry/IPR051573", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "bta:100141009", "url": "https://www.genome.jp/dbget-bin/www_bget?bta:100141009", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "DARNGCG", "url": "https://omabrowser.org/oma/group/DARNGCG/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "F1N349", "url": "https://www.orthodb.org/?gene=F1N349", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR24136", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR24136", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR24136:SF18", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR24136:SF18", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR24171", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR24171", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR24171:SF10", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR24171:SF10", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00023", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00023", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF07525", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF07525", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF12796", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF12796", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF13606", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF13606", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "NP_001289881", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001289881", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0AAA9TS08", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TS08", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0AAA9TS08-1", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TS08-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "F1N349", "url": "https://www.uniprot.org/uniprotkb/F1N349", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "F1N349-1", "url": "https://www.uniprot.org/uniprotkb/F1N349-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MSVSDRLPDYPVNSDFVKKLKAALEGRDEARLKDLICADVRHVDAVIELANDDWMKDPSAQLPPGVLVGDLEHLKPLMDKFFQDANVVFEIKKDEMVWQVKSPATFGLSGLWTLEYKRELTTPLCIAAAQGHTACVRHLLGRGADPDASPGGRGALHEACLGSHTACARLLLQHRADPDLLSAEGLAPLHLCRTAASLGCAQALLEHGASVQLEGGTSRDTPLHVAAQRGLDEHARLYLNRGARVDARNGHGETALSAACGAALRPDEHARCLRLCTLLLRHGAAADTRDEDERSPLHKACGHARPGLARLLLLHGADARALDYGGASPLARVLQTAACAPEGEPQLTVQELLNHGSPTVWPDAFPKVLKSCAAVPTVIEVLFNSYSQLRVSESWKDVIPEEVFQMHQAFYRSLFALAHTPRCLQHLCRCAIRKSFGRKCFSLVPLLPLPESLQNYLLLEPEGVLH", "length": 466, "header": "tr|F1N349-1|F1N349_BOVIN Isoform 1 of Ankyrin repeat and SOCS box containing 18 OS=Bos taurus OX=9913 GN=ASB18 PE=3 SV=2 CANONICAL=F1N349-1" }, "isoforms": [ { "isoform_ac": "A0AAA9TS08-1", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TS08/entry", "sequence": { "sequence": "MSVSDRLPDYPVNSDFVKKLKAALEGRDEARLKDLICADVRHVDAVIELANDDWMKDPSAQLPPGVLVGLWTLEYKRELTTPLCIAAAQGHTACVRHLLGRGADPDASPGGRGALHEACLGSHTACARLLLQHRADPDLLSAEGLAPLHLCRTAASLGCAQALLEHGASVQLEGGTSRDTPLHVAAQRGLDEHARLYLNRGARVDARNGHGETALSAACGAALRPDEHARCLRLCTLLLRHGAAADTRDEDERSPLHKACGHARPGLARLLLLHGADARALDYGGASPLARVLQTAACAPEGEPQLTVQELLNHGSPTVWPDAFPKVLKSCAAVPTVIEVLFNSYSQLRVSESWKDVIPEEVFQMHQAFYRSLFALAHTPRCLQHLCRCAIRKSFGRKCFSLVPLLPLPESLQNYLLLEPEGVLH", "length": 425, "header": "tr|A0AAA9TS08-1|F1N349_BOVIN Computationally mapped isoform of Ankyrin repeat and SOCS box containing 18 OS=Bos taurus OX=9913 GN=ASB18 PE=3 SV=1 CANONICAL=F1N349-1" }, "locus": { "chromosome": "3", "start_pos": 115735853, "end_pos": 115664208, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000124967.1", "url": "https://www.ensembl.org/id/ENSBTAT00000124967.1" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000099258.1", "url": "https://www.ensembl.org/id/ENSBTAP00000099258.1" } ] } }, { "isoform_ac": "F1N349-1", "url": "https://www.uniprot.org/uniprotkb/F1N349/entry", "sequence": { "sequence": "MSVSDRLPDYPVNSDFVKKLKAALEGRDEARLKDLICADVRHVDAVIELANDDWMKDPSAQLPPGVLVGDLEHLKPLMDKFFQDANVVFEIKKDEMVWQVKSPATFGLSGLWTLEYKRELTTPLCIAAAQGHTACVRHLLGRGADPDASPGGRGALHEACLGSHTACARLLLQHRADPDLLSAEGLAPLHLCRTAASLGCAQALLEHGASVQLEGGTSRDTPLHVAAQRGLDEHARLYLNRGARVDARNGHGETALSAACGAALRPDEHARCLRLCTLLLRHGAAADTRDEDERSPLHKACGHARPGLARLLLLHGADARALDYGGASPLARVLQTAACAPEGEPQLTVQELLNHGSPTVWPDAFPKVLKSCAAVPTVIEVLFNSYSQLRVSESWKDVIPEEVFQMHQAFYRSLFALAHTPRCLQHLCRCAIRKSFGRKCFSLVPLLPLPESLQNYLLLEPEGVLH", "length": 466, "header": "tr|F1N349-1|F1N349_BOVIN Isoform 1 of Ankyrin repeat and SOCS box containing 18 OS=Bos taurus OX=9913 GN=ASB18 PE=3 SV=2 CANONICAL=F1N349-1" }, "locus": { "chromosome": "3", "start_pos": 115735853, "end_pos": 115664208, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000002623.7", "url": "https://www.ensembl.org/id/ENSBTAT00000002623.7" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000002623.5", "url": "https://www.ensembl.org/id/ENSBTAP00000002623.5" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [ { "id": "bta:100141009", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?bta:100141009", "resource": "KEGG Pathway" } ], "orthologs": [ { "uniprot_canonical_ac": "D3ZU92-1", "protein_name": "Ankyrin repeat and SOCS box-containing 18", "gene_name": "Asb18", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MSGWDPPPDYPLSSDLVRRLKSALATGDRDTVQELICTEVEPVDAVLELANDDWMKEPSAKLPTGALLGDLDHIQSLTDQCFWDANVVFEISTEEMEWQVTSLATFGLSGLWTLEYKRELTTPLCIAAAHGHESCVRHLLSRKADPDASPGGRGALHEACLGSHTACARLLLQHGADPDLLSSEGLAPLHLCRTPASLGCAQELLEHGATVQLEGGPNRDTPLHVAAQRGLDKHAQLYLGCGARVDARNGRGETALSAACGAAARSPEEHARCLRLCALLLRGGAATDMRDEDERSPLHKACGHARPGLCTLLLRNGADADALDYGGASPLARALQTATCAPPTAPQRTVQALLNHGSRSVWPDAFPKVLRTCAPVPAVIEVLFNSYTQLRVSESWREAIPEEVYQMHKPFYRSLFALAHTPRCLQHFCRCAIRKLFGKECIHLVPQLPLPETLQNYLLLEPEGVLR", "length": 467 }, "evidence": [ { "id": "F1N349", "url": "https://omabrowser.org/oma/group/F1N349/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "F1SM12-1", "protein_name": "Ankyrin repeat and SOCS box containing 18", "gene_name": "ASB18", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MSISARLPDYPVTSDLVTRLKSALEAGDEERVRALACTEVRPVDAVIELANDDWMKDPSAQLPPGVLLGDMDRLKPLMDQFFQDANVVFEIKKDEMEWQGKSSGTFGLSGLWTLEYKRELTTPLCIAAAHGHTACVRHLLGRGADPDASPGGRGALHEACLGGHTACARLLLQHRADADLLSAEGLAPLHLCRTAASLGCAQALLEHGASVRRAGGAGLDTPLHVAARHGLDEHALLYLGRGASVDARNGRGETALSVACGAARRPDEHARCLRLCALLLRGGAAADARDEDERSPLHKACGRARHDLARLLLRHGADVGALDYGGATPLACVLQTAACAREAAPHRTVQALLNHGSPTVWPDAFSKVLKTCAPAPTTVEVLFNSYPQLRVSESWKEVIPEEVFQVHQAFYQSLLALAHAPRSLQHLCRCAIRKVFGGKCFCLVPLLPLPPSLQDFLLLEPEGVLH", "length": 466 }, "evidence": [ { "id": "F1N349", "url": "https://omabrowser.org/oma/group/F1N349/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "Q6ZVZ8-1", "protein_name": "Ankyrin repeat and SOCS box protein 18", "gene_name": "ASB18", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MSNSDYLPDYPLNSDLVKRLKSALDAKDEERVRDLICTEITPVDAVIELANDDWMKDPSAQLPTGMLLGDLDHLKPLMDQFFQDANVVFEINKDEMEWQVKSPATFGLSGLWTLEYKRELTTPLCIAAAHGHTACVRHLLGRGADPDASPGGRGALHEACLGGHTACVRLLLQHRADPDLLSAEGLAPLHLCRTAASLGCAQALLEHGASVQRVGGTGRDTPLHVAAQRGLDEHARLYLGRGAHVDARNGRGETALSAACGAARRPDEHGRCLRLCALLLRRGAEADARDEDERSPLHKACGHASHSLARLLLRHGADAGALDYGGASPLGRVLQTASCALQASPQRTVQALLNHGSPTVWPDAFPKVLKTCASVPAVIEVLFNSYPQLCLSESWKEVIPEEVFQMHKPFYQSLFALALTPRCLQHLCRCALRRLFGKRCFDLIPLLPLPKPLQNYLLLEPQGVLH", "length": 466 }, "evidence": [ { "id": "F1N349", "url": "https://omabrowser.org/oma/group/F1N349/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "Q8VHA6-1", "protein_name": "Ankyrin repeat and SOCS box protein 18", "gene_name": "Asb18", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MSSWDSPPDYPLSSDIVRRLKSALATGDEDTVQKLICTEVEPVDAVIELANDDWMKEPSAELPTGVLLGDLDHIRLLMDQCFWDANAVFEISNGEMEWQVTSLATFGLSGLWTLEYQRELTTPLCIAAAHGHESCVRHLLSRKADPNASPGGRGALHEACLGNHTACARLLLQHGADPDLLNSEGLAPLHLCRTPASLGCARELLEHGATVQLEGGPGRDTPLHVAAQRGLDEHAQLYLGFGARVDARNGRGETALSAACGAAARSPDEHARCLRLCALLLRGGAAADARDEDERSPLHKACGHARPGLCTLLLRHGADAGALDYGGASPLARALQTATCAPPTAPQRTVQVLLNHGSRSVWPDAFPKVLRTCAQVPEVIEVLFNSYTQLPVSESWREAIPEEVYQMHKPFYRSLFALAHTPRCLQHLCRCTIRKLFGKESVHLVPQLPLPETLQNYLLLEPEGVLC", "length": 467 }, "evidence": [ { "id": "F1N349", "url": "https://omabrowser.org/oma/group/F1N349/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" } ], "go_annotation": { "categories": [ { "name": "Biological Process", "total": 2, "go_terms": [ { "name": "intracellular signal transduction", "id": "GO:0035556", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0035556", "evidence": [ { "database": "UniProtKB", "id": "F1N349", "url": "https://www.uniprot.org/uniprotkb/F1N349" } ], "pmid": "" }, { "name": "protein ubiquitination", "id": "GO:0016567", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016567", "evidence": [ { "database": "UniProtKB", "id": "F1N349", "url": "https://www.uniprot.org/uniprotkb/F1N349" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 1, "go_terms": [ { "name": "cytosol", "id": "GO:0005829", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005829", "evidence": [ { "database": "UniProtKB", "id": "F1N349", "url": "https://www.uniprot.org/uniprotkb/F1N349" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [ { "pdb_id": "AF-F1N349-F1", "pdb_chain": "global", "start_pos": 1, "end_pos": 466, "overlap": "1.0", "method": "AlphaFold", "type": "alphafold", "resolution": -1.0, "url": "https://data.glygen.org/ln2downloads/pdb/current/AF-F1N349-F1.pdb", "url_external": "https://alphafold.ebi.ac.uk/entry/F1N349" } ], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "F1N349", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1N349" }, { "id": "PS50225", "database": "PROSITE", "url": "https://prosite.expasy.org/PS50225" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "SOCS box", "eco_id": "ECO_0000259", "start_pos": 421, "end_pos": 457, "start_aa": "Pro", "end_aa": "Leu", "glycosite_overlap": [] } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" }, { "name": "homologset.oma", "label": "OMA Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ], "tool_support": { "graph_view": "yes" } }, { "uniprot_canonical_ac": "F1N4M3-1", "uniprot_ac": "F1N4M3", "uniprot_id": "F1N4M3_BOVIN", "mass": { "chemical_mass": 98940.0, "monoisotopic_mass": 98940.0 }, "refseq": {}, "gene_names": [ { "name": "PDPR", "type": "recommended", "evidence": [ { "id": "F1N4M3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1N4M3" } ] } ], "protein_names": [ { "name": "Pyruvate dehydrogenase phosphatase regulatory subunit, mitochondrial", "type": "recommended", "evidence": [ { "id": "F1N4M3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1N4M3/entry#names_and_taxonomy" } ] } ], "function": [ { "annotation": "Decreases the sensitivity of PDP1 to magnesium ions, and this inhibition is reversed by the polyamine spermine.", "evidence": [ { "database": "UniProtKB", "id": "A0AAA9TT84", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TT84#function" }, { "database": "UniProtKB", "id": "ARBA00053434", "url": "https://www.uniprot.org/uniprotkb/ARBA00053434#function" }, { "database": "UniProtKB", "id": "F1N4M3", "url": "https://www.uniprot.org/uniprotkb/F1N4M3#function" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Bos taurus", "taxid": 9913, "evidence": [ { "database": "UniProtKB", "id": "F1N4M3", "url": "https://www.uniprot.org/uniprotkb/F1N4M3" } ], "common_name": "Bovine", "glygen_name": "Bovine", "reference_species": "Bos taurus [9913]" } ], "gene": [ { "name": "PDPR", "url": "https://www.uniprot.org/uniprotkb/F1N4M3", "locus": { "chromosome": "18", "start_pos": 1880242, "end_pos": 1920488, "strand": "+", "evidence": [ { "database": "Ensembl Gene", "id": "ENSBTAG00000016471", "url": "https://www.ensembl.org/id/ENSBTAG00000016471" } ] } } ], "crossref": [ { "id": "F1N4M3", "url": "https://alphafold.ebi.ac.uk/entry/F1N4M3", "database": "AlphaFoldDB", "categories": [] }, { "id": "ENSBTAG00000016471", "url": "https://bgee.org/?page=gene&gene_id=ENSBTAG00000016471", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "IPR001763", "url": "https://www.ebi.ac.uk/interpro/entry/IPR001763", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR006076", "url": "https://www.ebi.ac.uk/interpro/entry/IPR006076", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR006222", "url": "https://www.ebi.ac.uk/interpro/entry/IPR006222", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR013977", "url": "https://www.ebi.ac.uk/interpro/entry/IPR013977", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR027266", "url": "https://www.ebi.ac.uk/interpro/entry/IPR027266", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR028896", "url": "https://www.ebi.ac.uk/interpro/entry/IPR028896", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR029043", "url": "https://www.ebi.ac.uk/interpro/entry/IPR029043", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR032503", "url": "https://www.ebi.ac.uk/interpro/entry/IPR032503", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR036188", "url": "https://www.ebi.ac.uk/interpro/entry/IPR036188", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "F1N4M3", "url": "https://www.orthodb.org/?gene=F1N4M3", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR43757", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR43757", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR43757:SF15", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR43757:SF15", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF01266", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF01266", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF01571", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF01571", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF08669", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF08669", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF16350", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF16350", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "R-BTA-204174", "url": "https://www.reactome.org/PathwayBrowser/#R-BTA-204174", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "A0AAA9TT84", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TT84", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0AAA9TT84-1", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TT84-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "F1N4M3", "url": "https://www.uniprot.org/uniprotkb/F1N4M3", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "F1N4M3-1", "url": "https://www.uniprot.org/uniprotkb/F1N4M3-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "VMLPRLLAVVRGPGSCRGWREGSPARGSASATVAPPVALPAQAQVVVCGGGIMGTSVAYHLSKMGWKDVVLLEQGRLAAGSTRFCAGILSTARHLAIEQKMADYSNKLYHQLEQETGIQTGYTRTGSIFLAQTQDRLISLKRINSRLNVIGIPCEIISPKKVAELHPLLNVHDLVGAMHVPEDAVVSSADVALALASAASQSGVQIYDRTSILHVMVKKGQVAGVETDKGQIQCQYFVNCAGQWAYELGLCSEEPVSIPLHACEHFYLLTRPWETPLPSSTPTVVDADGRIYIRNWQGGILSGGFEKNPKPIFTEGKNQLEIQNLQEDWDHFEPLLSSLLRRMPQLETLEIVKLVNCPETFTPDMRCIMGESPSVRGYFVLVGMNSAGLSFGGGAGKYLAEWMVYGYPSENVWELDLKRFGALQSSRTFLRHRVMEVMPLLYDLKVPRWDFQTGRQLRTSPLYDRLDAQGARWMEKHGFERPKYFIPPDKDLLALEQSKTFYKPDWFEIVESEVKCCKEAVCVIDMSSFTKFEITSTGDQALEILQYLFSNDLDVPVGHIVHTGMLNERGGYENDCSIARLSKRSFFMISPTDQQVHCWAWLKKYMPEDSNLILEDVTWKYTALNLIGPRAVDVLSELSYAPMTPDHFPSLFCKEMSVGYANGIRVMSMTHTGEPGFMLYIPIEYALHVYNEVMSVGQKYGIRNAGYYALRSLRIEKFFAFWGQDLNTLTTPLECGGESRVKLDKGVDFIGRDALLQQRQNGVYKRLTMFILDDHDTDLDLWPWWGEPIYRNGRYVGKTTSSAYGYTLERHVCLGFVHNFSEDTGEEQVVTADFINRGEYEIDIAGHRFQAKAKLYPVPSLLTHKRRKEDVELSDLHGK", "length": 879, "header": "tr|F1N4M3-1|F1N4M3_BOVIN Isoform 1 of Pyruvate dehydrogenase phosphatase regulatory subunit, mitochondrial OS=Bos taurus OX=9913 GN=PDPR PE=3 SV=3 CANONICAL=F1N4M3-1" }, "isoforms": [ { "isoform_ac": "A0AAA9TT84-1", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TT84/entry", "sequence": { "sequence": "MLPRLLAVVRGPGSCRGWREGSPARGSASATVAPPVALPAQAQVVVCGGGIMGTSVAYHLSKMGWKDVVLLEQGRLAAGSTRFCAGILSTARHLAIEQKMADYSNKLYHQLEQETGIQTGYTRTGSIFLAQTQDRLISLKRINSRLNVIGIPCEIISPKKVAELHPLLNVHDLVGAMHVPEDAVVSSADVALALASAASQSAVVDADGRIYIRNWQGGILSGGFEKNPKPIFTEGKNQLEIQNLQEDWDHFEPLLSSLLRRMPQLETLEIVKLVNCPETFTPDMRCIMGESPSVRGYFVLVGMNSAGLSFGGGAGKYLAEWMVYGYPSENVWELDLKRFGALQSSRTFLRHRVMEVMPLLYDLKVPRWDFQTGRQLRTSPLYDRLDAQGARWMEKHGFERPKYFIPPDKDLLALEQSKTFYKPDWFEIVESEVKCCKEAVCVIDMSSFTKFEITSTGDQALEILQYLFSNDLDVPVGHIVHTGMLNERGGYENDCSIARLSKRSFFMISPTDQQVHCWAWLKKYMPEDSNLILEDVTWKYTALNLIGPRAVDVLSELSYAPMTPDHFPSLFCKEMSVGYANGIRVMSMTHTGEPGFMLYIPIEYALHVYNEVMSVGQKYGIRNAGYYALRSLRIEKFFAFWGQDLNTLTTPLECGGESRVKLDKGVDFIGRDALLQQRQNGVYKRLTMFILDDHDTDLDLWPWWGEPIYRNGRYVGKTTSSAYGYTLERHVCLGFVHNFSEDTGEEQVVTADFINRGEYEIDIAGHRFQAKAKLYPVPSLLTHKRRKEDVELSDLHGK", "length": 798, "header": "tr|A0AAA9TT84-1|F1N4M3_BOVIN Computationally mapped isoform of Pyruvate dehydrogenase phosphatase regulatory subunit, mitochondrial OS=Bos taurus OX=9913 GN=PDPR PE=3 SV=1 CANONICAL=F1N4M3-1" }, "locus": { "chromosome": "18", "start_pos": 1909291, "end_pos": 1880344, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000099234.1", "url": "https://www.ensembl.org/id/ENSBTAT00000099234.1" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000100278.1", "url": "https://www.ensembl.org/id/ENSBTAP00000100278.1" } ] } }, { "isoform_ac": "F1N4M3-1", "url": "https://www.uniprot.org/uniprotkb/F1N4M3/entry", "sequence": { "sequence": "VMLPRLLAVVRGPGSCRGWREGSPARGSASATVAPPVALPAQAQVVVCGGGIMGTSVAYHLSKMGWKDVVLLEQGRLAAGSTRFCAGILSTARHLAIEQKMADYSNKLYHQLEQETGIQTGYTRTGSIFLAQTQDRLISLKRINSRLNVIGIPCEIISPKKVAELHPLLNVHDLVGAMHVPEDAVVSSADVALALASAASQSGVQIYDRTSILHVMVKKGQVAGVETDKGQIQCQYFVNCAGQWAYELGLCSEEPVSIPLHACEHFYLLTRPWETPLPSSTPTVVDADGRIYIRNWQGGILSGGFEKNPKPIFTEGKNQLEIQNLQEDWDHFEPLLSSLLRRMPQLETLEIVKLVNCPETFTPDMRCIMGESPSVRGYFVLVGMNSAGLSFGGGAGKYLAEWMVYGYPSENVWELDLKRFGALQSSRTFLRHRVMEVMPLLYDLKVPRWDFQTGRQLRTSPLYDRLDAQGARWMEKHGFERPKYFIPPDKDLLALEQSKTFYKPDWFEIVESEVKCCKEAVCVIDMSSFTKFEITSTGDQALEILQYLFSNDLDVPVGHIVHTGMLNERGGYENDCSIARLSKRSFFMISPTDQQVHCWAWLKKYMPEDSNLILEDVTWKYTALNLIGPRAVDVLSELSYAPMTPDHFPSLFCKEMSVGYANGIRVMSMTHTGEPGFMLYIPIEYALHVYNEVMSVGQKYGIRNAGYYALRSLRIEKFFAFWGQDLNTLTTPLECGGESRVKLDKGVDFIGRDALLQQRQNGVYKRLTMFILDDHDTDLDLWPWWGEPIYRNGRYVGKTTSSAYGYTLERHVCLGFVHNFSEDTGEEQVVTADFINRGEYEIDIAGHRFQAKAKLYPVPSLLTHKRRKEDVELSDLHGK", "length": 879, "header": "tr|F1N4M3-1|F1N4M3_BOVIN Isoform 1 of Pyruvate dehydrogenase phosphatase regulatory subunit, mitochondrial OS=Bos taurus OX=9913 GN=PDPR PE=3 SV=3 CANONICAL=F1N4M3-1" }, "locus": { "chromosome": "18", "start_pos": 1909294, "end_pos": 1880344, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000021895.4", "url": "https://www.ensembl.org/id/ENSBTAT00000021895.4" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000021895.3", "url": "https://www.ensembl.org/id/ENSBTAP00000021895.3" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [ { "id": "R-BTA-204174", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-BTA-204174", "resource": "Reactome", "description": "Regulation of pyruvate dehydrogenase (PDH) complex" } ], "orthologs": [], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 3, "go_terms": [ { "name": "mitochondrial matrix", "id": "GO:0005759", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005759", "evidence": [ { "database": "UniProtKB", "id": "F1N4M3", "url": "https://www.uniprot.org/uniprotkb/F1N4M3" } ], "pmid": "" }, { "name": "cytoplasm", "id": "GO:0005737", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005737", "evidence": [ { "database": "UniProtKB", "id": "F1N4M3", "url": "https://www.uniprot.org/uniprotkb/F1N4M3" } ], "pmid": "" }, { "name": "mitochondrion", "id": "GO:0005739", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005739", "evidence": [ { "database": "UniProtKB", "id": "F1N4M3", "url": "https://www.uniprot.org/uniprotkb/F1N4M3" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 819, "end_pos": 821, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [ { "pdb_id": "AF-F1N4M3-F1", "pdb_chain": "global", "start_pos": 1, "end_pos": 879, "overlap": "1.0", "method": "AlphaFold", "type": "alphafold", "resolution": -1.0, "url": "https://data.glygen.org/ln2downloads/pdb/current/AF-F1N4M3-F1.pdb", "url_external": "https://alphafold.ebi.ac.uk/entry/F1N4M3" } ], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "F1N4M3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1N4M3" }, { "id": "PS50206", "database": "PROSITE", "url": "https://prosite.expasy.org/PS50206" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "Rhodanese", "eco_id": "ECO_0000259", "start_pos": 45, "end_pos": 88, "start_aa": "Val", "end_aa": "Ile", "glycosite_overlap": [] } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 819, "end_pos": 821 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ], "tool_support": { "graph_view": "yes" } }, { "uniprot_canonical_ac": "F1N2Q8-1", "uniprot_ac": "F1N2Q8", "uniprot_id": "F1N2Q8_BOVIN", "mass": { "chemical_mass": 361718.0, "monoisotopic_mass": 361718.0 }, "refseq": { "ac": "XP_010802062", "name": "KICSTOR complex protein SZT2 isoform X2", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_010802062" }, "gene_names": [ { "name": "SZT2", "type": "recommended", "evidence": [ { "id": "F1N2Q8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1N2Q8" } ] }, { "name": "SZT2", "type": "synonym", "evidence": [ { "id": "XP_010802062", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_010802062" } ] } ], "protein_names": [ { "name": "KICSTOR complex protein SZT2 isoform X2", "type": "synonym", "evidence": [ { "id": "XP_010802062", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_010802062" } ] }, { "name": "SZT2 subunit of KICSTOR complex", "type": "synonym", "evidence": [ { "id": "F1N2Q8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1N2Q8/entry#names_and_taxonomy" } ] } ], "function": [], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Bos taurus", "taxid": 9913, "evidence": [ { "database": "UniProtKB", "id": "F1N2Q8", "url": "https://www.uniprot.org/uniprotkb/F1N2Q8" } ], "common_name": "Bovine", "glygen_name": "Bovine", "reference_species": "Bos taurus [9913]" } ], "gene": [ { "name": "SZT2", "url": "https://www.uniprot.org/uniprotkb/F1N2Q8", "locus": { "chromosome": "3", "start_pos": 102575578, "end_pos": 102629407, "strand": "+", "evidence": [ { "database": "Ensembl Gene", "id": "ENSBTAG00000005580", "url": "https://www.ensembl.org/id/ENSBTAG00000005580" } ] } } ], "crossref": [ { "id": "ENSBTAG00000005580", "url": "https://bgee.org/?page=gene&gene_id=ENSBTAG00000005580", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "533805", "url": "https://www.ncbi.nlm.nih.gov/gene/533805", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR033228", "url": "https://www.ebi.ac.uk/interpro/entry/IPR033228", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "F1N2Q8", "url": "https://www.orthodb.org/?gene=F1N2Q8", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR14918", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR14918", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR14918:SF3", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR14918:SF3", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "R-BTA-9639288", "url": "https://www.reactome.org/PathwayBrowser/#R-BTA-9639288", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "XP_010802062", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_010802062", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "F1N2Q8", "url": "https://www.uniprot.org/uniprotkb/F1N2Q8", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "F1N2Q8-1", "url": "https://www.uniprot.org/uniprotkb/F1N2Q8-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": 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{ "name": "cellular response to amino acid starvation", "id": "GO:0034198", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0034198", "evidence": [ { "database": "UniProtKB", "id": "F1N2Q8", "url": "https://www.uniprot.org/uniprotkb/F1N2Q8" } ], "pmid": "" }, { "name": "negative regulation of TORC1 signaling", "id": "GO:1904262", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:1904262", "evidence": [ { "database": "UniProtKB", "id": "F1N2Q8", "url": "https://www.uniprot.org/uniprotkb/F1N2Q8" } ], "pmid": "" }, { "name": "corpus callosum morphogenesis", "id": "GO:0021540", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0021540", "evidence": [ { "database": "UniProtKB", "id": "F1N2Q8", "url": "https://www.uniprot.org/uniprotkb/F1N2Q8" } ], "pmid": "" }, { "name": "protein localization to lysosome", "id": "GO:0061462", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0061462", "evidence": [ { "database": "UniProtKB", "id": "F1N2Q8", "url": "https://www.uniprot.org/uniprotkb/F1N2Q8" } ], "pmid": 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"IPR036051", "url": "https://www.ebi.ac.uk/interpro/entry/IPR036051", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR036236", "url": "https://www.ebi.ac.uk/interpro/entry/IPR036236", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR038269", "url": "https://www.ebi.ac.uk/interpro/entry/IPR038269", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "PTHR23226", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR23226", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR23226:SF416", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR23226:SF416", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR24399", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR24399", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR24399:SF54", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR24399:SF54", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00096", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00096", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF01352", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF01352", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF02023", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF02023", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "A0ABI0NPK1", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NPK1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0ABI0NPK1-1", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NPK1-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "F6QJ16", "url": "https://www.uniprot.org/uniprotkb/F6QJ16", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "F6QJ16-1", "url": "https://www.uniprot.org/uniprotkb/F6QJ16-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MSWSWTASQSTIAPPALGDGLWTVKVEEDSFGSGESDRPWDCPDPETFRCHFRQFRYQEVAGPEEALSRLRELCCRWLRPEVHSKEQILELLVLEQFLTILPQEIQAWVRKHCPQSGEEAAAVVRSLQRQPAGTSRQGLVTVRDVAVSLTWEEWERLYPAQKHFFRESAPKDHGNAVSPSSETRIVNKELIPKQEILEVELQGQLQGFQEKAPLSSECGDAQDRREKSLGDPSSLKRENSPEDQGVTHISDLRNGPSEEGDVKNKEFRTSAESSDFVAGQYVPTAGRPATGDEYGNNCQHRLDMVKPHESLNSEENRHHSGLFETQRWFHEERPYTCDTCEKSFKQRSDLLKHHRIHTGERPYGCSVCGRRFSQSATLIKHQRTHTGEKPYTCPRCGDSFRQSSNLSRHQRTHLGEKHYTCNNFRETCHTSSHFSHQRTHNEERPYLCEECDKSFKRCSDLSKHQRIHTGEKPYGCPVCGRRFSQSATLIKHQRTHTGEKPYTCPKCGDSFRQSSHLSRHQRTHLGEKHYTCKECGENCRTSSRFRHQRTHKAERPHTCEECNKSFKRSSDLSKHQRIHTESHVFSLEGHMVSM", "length": 594, "header": "tr|F6QJ16-1|F6QJ16_BOVIN Isoform 1 of Zinc finger protein 394 OS=Bos taurus OX=9913 GN=ZNF394 PE=3 SV=1 CANONICAL=F6QJ16-1" }, "isoforms": [ { "isoform_ac": "A0ABI0NPK1-1", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NPK1/entry", "sequence": { "sequence": "MSWSWTASQSTIAPPALGDGLWTVKVEEDSFGSGESDRPWDCPDPETFRCHFRQFRYQEVAGPEEALSRLRELCCRWLRPEVHSKEQILELLVLEQFLTILPQEIQAWVRKHCPQSGEEAAAVVRSLQRQPAGTSRQGLVTVRDVAVSLTWEEWERLYPAQKHFFRESAPKDHGNAVSPSSETRIVNKELIPKQEILEVELQGQLQGFQEKAPLSSECGDAQDRREKSLGDPSSLKRENSPEDQGVTHISDLRNGPSEEGDVKNKEFRTSAESSDFVAGQYVPTAGRPATGDEYGNNCQHRLDMVKPHESLNSEENRHHSGLFETQRWFHEERPYTCDTCEKSFKQRSDLLKHHRIHTGERPYGCSVCGRRFSQSATLIKHQRTHTGEKPYTCPKCGDSFRQSSHLSRHQRTHLGEKHYTCKECGENCRTSSRFRHQRTHKAERPHTCEECNKSFKRSSDLSKHQRIHTGEKPYGCSVCGKHFSQSATLIKHRRTHTGEKPYRCLDCGGSFRQSSHLVRHQRIHRNKVPSF", "length": 531, "header": "tr|A0ABI0NPK1-1|A0ABI0NPK1_BOVIN Computationally mapped isoform of Zinc finger protein 394 OS=Bos taurus OX=9913 GN=ZNF394 PE=3 SV=1 CANONICAL=F6QJ16-1" }, "locus": { "chromosome": "25", "start_pos": 36923688, "end_pos": 36910911, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000138668.1", "url": "https://www.ensembl.org/id/ENSBTAT00000138668.1" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000107621.1", "url": "https://www.ensembl.org/id/ENSBTAP00000107621.1" } ] } }, { "isoform_ac": "F6QJ16-1", "url": "https://www.uniprot.org/uniprotkb/F6QJ16/entry", "sequence": { "sequence": "MSWSWTASQSTIAPPALGDGLWTVKVEEDSFGSGESDRPWDCPDPETFRCHFRQFRYQEVAGPEEALSRLRELCCRWLRPEVHSKEQILELLVLEQFLTILPQEIQAWVRKHCPQSGEEAAAVVRSLQRQPAGTSRQGLVTVRDVAVSLTWEEWERLYPAQKHFFRESAPKDHGNAVSPSSETRIVNKELIPKQEILEVELQGQLQGFQEKAPLSSECGDAQDRREKSLGDPSSLKRENSPEDQGVTHISDLRNGPSEEGDVKNKEFRTSAESSDFVAGQYVPTAGRPATGDEYGNNCQHRLDMVKPHESLNSEENRHHSGLFETQRWFHEERPYTCDTCEKSFKQRSDLLKHHRIHTGERPYGCSVCGRRFSQSATLIKHQRTHTGEKPYTCPRCGDSFRQSSNLSRHQRTHLGEKHYTCNNFRETCHTSSHFSHQRTHNEERPYLCEECDKSFKRCSDLSKHQRIHTGEKPYGCPVCGRRFSQSATLIKHQRTHTGEKPYTCPKCGDSFRQSSHLSRHQRTHLGEKHYTCKECGENCRTSSRFRHQRTHKAERPHTCEECNKSFKRSSDLSKHQRIHTESHVFSLEGHMVSM", "length": 594, "header": "tr|F6QJ16-1|F6QJ16_BOVIN Isoform 1 of Zinc finger protein 394 OS=Bos taurus OX=9913 GN=ZNF394 PE=3 SV=1 CANONICAL=F6QJ16-1" }, "locus": { "chromosome": "25", "start_pos": 36925523, "end_pos": 36910911, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000021549.7", "url": "https://www.ensembl.org/id/ENSBTAT00000021549.7" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000021549.5", "url": "https://www.ensembl.org/id/ENSBTAP00000021549.5" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [], "orthologs": [], "go_annotation": { "categories": [ { "name": "Molecular Function", "total": 2, "go_terms": [ { "name": "DNA binding", "id": "GO:0003677", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003677", "evidence": [ { "database": "UniProtKB", "id": "F6QJ16", "url": "https://www.uniprot.org/uniprotkb/F6QJ16" } ], "pmid": "" }, { "name": "zinc ion binding", "id": "GO:0008270", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008270", "evidence": [ { "database": "UniProtKB", "id": "F6QJ16", "url": "https://www.uniprot.org/uniprotkb/F6QJ16" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 2, "go_terms": [ { "name": "nucleoplasm", "id": "GO:0005654", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005654", "evidence": [ { "database": "UniProtKB", "id": "F6QJ16", "url": "https://www.uniprot.org/uniprotkb/F6QJ16" } ], "pmid": "" }, { "name": "nucleus", "id": "GO:0005634", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005634", "evidence": [ { "database": "UniProtKB", "id": "F6QJ16", "url": "https://www.uniprot.org/uniprotkb/F6QJ16" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 2, "go_terms": [ { "name": "DNA-templated transcription", "id": "GO:0006351", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006351", "evidence": [ { "database": "UniProtKB", "id": "F6QJ16", "url": "https://www.uniprot.org/uniprotkb/F6QJ16" } ], "pmid": "" }, { "name": "regulation of DNA-templated transcription", "id": "GO:0006355", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006355", "evidence": [ { "database": "UniProtKB", "id": "F6QJ16", "url": "https://www.uniprot.org/uniprotkb/F6QJ16" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 405, "end_pos": 407, "annotation": "n_glycosylation_sequon" }, { "start_pos": 563, "end_pos": 565, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "F6QJ16", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F6QJ16" }, { "id": "PS50157", "database": "PROSITE", "url": "https://prosite.expasy.org/PS50157" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "C2H2-type", "eco_id": "ECO_0000259", "start_pos": 335, "end_pos": 362, "start_aa": "Tyr", "end_aa": "Pro", "glycosite_overlap": [] }, { "evidence": [ { "id": "F6QJ16", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F6QJ16" }, { "id": "PS50805", "database": "PROSITE", "url": "https://prosite.expasy.org/PS50805" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "KRAB", "eco_id": "ECO_0000259", "start_pos": 140, "end_pos": 213, "start_aa": "Val", "end_aa": "Pro", "glycosite_overlap": [] }, { "evidence": [ { "id": "F6QJ16", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F6QJ16" }, { "id": "PS50804", "database": "PROSITE", "url": "https://prosite.expasy.org/PS50804" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "SCAN box", "eco_id": "ECO_0000259", "start_pos": 49, "end_pos": 130, "start_aa": "Arg", "end_aa": "Gln", "glycosite_overlap": [] } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 405, "end_pos": 407 }, { "start_pos": 563, "end_pos": 565 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": 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"o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ], "tool_support": { "graph_view": "yes" } }, { "uniprot_canonical_ac": "F1N2Q9-1", "uniprot_ac": "F1N2Q9", "uniprot_id": "F1N2Q9_BOVIN", "mass": { "chemical_mass": 22530.0, "monoisotopic_mass": 22530.0 }, "refseq": { "ac": "NP_001178993", "name": "GTP-binding protein Di-Ras2", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001178993" }, "gene_names": [ { "name": "DIRAS2", "type": "recommended", "evidence": [ { "id": "F1N2Q9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1N2Q9" } ] }, { "name": "DIRAS2", "type": "synonym", "evidence": [ { "id": "NP_001178993", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001178993" } ] } ], "protein_names": [ { "name": "DIRAS family GTPase 2", "type": "synonym", "evidence": [ { "id": "F1N2Q9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1N2Q9/entry#names_and_taxonomy" } ] }, { "name": "GTP-binding protein Di-Ras2", "type": "synonym", "evidence": [ { "id": "NP_001178993", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001178993" } ] } ], "function": [ { "annotation": "Displays low GTPase activity and exists predominantly in the GTP-bound form.", "evidence": [ { "database": "UniProtKB", "id": "F1N2Q9", "url": "https://www.uniprot.org/uniprotkb/F1N2Q9#function" }, { "database": "UniProtKB", "id": "ARBA00055536", "url": "https://www.uniprot.org/uniprotkb/ARBA00055536#function" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Bos taurus", "taxid": 9913, "evidence": [ { "database": "UniProtKB", "id": "F1N2Q9", "url": "https://www.uniprot.org/uniprotkb/F1N2Q9" } ], "common_name": "Bovine", "glygen_name": "Bovine", "reference_species": "Bos taurus [9913]" } ], "gene": [ { "name": "DIRAS2", "url": "https://www.uniprot.org/uniprotkb/F1N2Q9", "locus": { "chromosome": "8", "start_pos": 87262933, "end_pos": 87225193, "strand": "-", "evidence": [ { "database": "Ensembl Gene", "id": "ENSBTAG00000014523", "url": "https://www.ensembl.org/id/ENSBTAG00000014523" } ] } } ], "crossref": [ { "id": "ENSBTAG00000014523", "url": "https://bgee.org/?page=gene&gene_id=ENSBTAG00000014523", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "cd04140", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd04140", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "538667", "url": "https://www.ncbi.nlm.nih.gov/gene/538667", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR001806", "url": "https://www.ebi.ac.uk/interpro/entry/IPR001806", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR005225", "url": "https://www.ebi.ac.uk/interpro/entry/IPR005225", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR020849", "url": "https://www.ebi.ac.uk/interpro/entry/IPR020849", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR027417", "url": "https://www.ebi.ac.uk/interpro/entry/IPR027417", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "bta:538667", "url": "https://www.genome.jp/dbget-bin/www_bget?bta:538667", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "CKETNGA", "url": "https://omabrowser.org/oma/group/CKETNGA/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "F1N2Q9", "url": "https://www.orthodb.org/?gene=F1N2Q9", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR24070", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR24070", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00071", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00071", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "NP_001178993", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001178993", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "F1N2Q9", "url": "https://www.uniprot.org/uniprotkb/F1N2Q9", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "F1N2Q9-1", "url": "https://www.uniprot.org/uniprotkb/F1N2Q9-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MPEQSNDYRVAVFGAGGVGKSSLVLRFVKGTFRESYIPTVEDTYRQVISCDKSICTLQITDTTGSHQFPAMQRLSISKGHAFILVYSITSRQSLEELKPIYEQICEIKGDVESIPIMLVGNKCDESPNREVESSEAEVLARKWKCAFMETSAKLNLNVKELFQELLNLEKRRTVSLQIDGKKSKQQKRKEKLKGKCVVM", "length": 199, "header": "tr|F1N2Q9-1|F1N2Q9_BOVIN Isoform 1 of DIRAS family GTPase 2 OS=Bos taurus OX=9913 GN=DIRAS2 PE=3 SV=2 CANONICAL=F1N2Q9-1" }, "isoforms": [ { "isoform_ac": "F1N2Q9-1", "url": "https://www.uniprot.org/uniprotkb/F1N2Q9/entry", "sequence": { "sequence": "MPEQSNDYRVAVFGAGGVGKSSLVLRFVKGTFRESYIPTVEDTYRQVISCDKSICTLQITDTTGSHQFPAMQRLSISKGHAFILVYSITSRQSLEELKPIYEQICEIKGDVESIPIMLVGNKCDESPNREVESSEAEVLARKWKCAFMETSAKLNLNVKELFQELLNLEKRRTVSLQIDGKKSKQQKRKEKLKGKCVVM", "length": 199, "header": "tr|F1N2Q9-1|F1N2Q9_BOVIN Isoform 1 of DIRAS family GTPase 2 OS=Bos taurus OX=9913 GN=DIRAS2 PE=3 SV=2 CANONICAL=F1N2Q9-1" }, "locus": { "chromosome": "8", "start_pos": 87259588, "end_pos": 87258992, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000119773.1", "url": "https://www.ensembl.org/id/ENSBTAT00000119773.1" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000102928.1", "url": "https://www.ensembl.org/id/ENSBTAP00000102928.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [ { "id": "bta:538667", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?bta:538667", "resource": "KEGG Pathway" } ], "orthologs": [ { "uniprot_canonical_ac": "A0A287AKH0-1", "protein_name": "DIRAS family GTPase 2", "gene_name": "DIRAS2", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MPEQSNDYRVAVFGAGGVGKSSLVLRFVKGTFRESYIPTVEDTYRQVISCDKSICTLQITDTTGSHQFPAMQRLSISKGHAFILVYSITSRQSLEELKPIYEQICEIKGDVESIPIMLVGNKCDESPNREVESSEAEALARKWKCAFMETSAKLNHNVKELFQELLNLEKRRTVSLQIDGKKSKQQKRKEKLKGKCVIM", "length": 199 }, "evidence": [ { "id": "F1N2Q9", "url": "https://omabrowser.org/oma/group/F1N2Q9/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "A0A8I5ZKR8-1", "protein_name": "DIRAS family GTPase 2", "gene_name": "Diras2", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MPEQSNDYRVAVFGAGGVGKSSLVLRFVKGTFRESYIPTVEDTYRQVISCDKSICTLQITDTTGSHQFPAMQRLSISKGHAFILVYSITSRQSLEELKPIYEQICEIKGDVESIPIMLVGNKCDESPNREVQSSEAEALARTWKCAFMETSAKLNHNVKELFQELLNLEKRRTVSLQIDGKKSKQQKRKEKLKGKCVVM", "length": 199 }, "evidence": [ { "id": "F1N2Q9", "url": "https://omabrowser.org/oma/group/F1N2Q9/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "E1C055-1", "protein_name": "DIRAS family GTPase 2", "gene_name": "DIRAS2", "tax_id": 9031, "organism": "Gallus gallus", "sequence": { "sequence": "MPEQSNDYRVVVFGAGGVGKSSLVLRFVKGTFRESYIPTIEDTYRQVISCDKSICTLQITDTTGSHQFPAMQRLSISKGHAFILVYSITSRQSLEELKPIYEQICQIKGDVESIPIMLVGNKNDENQNREVESSEGEATAKKWKCAFMETSAKLNHNVKELFQELLNLEKRRTVSLQIDGKKSKQQKRKEKLKGKCVVM", "length": 199 }, "evidence": [ { "id": "F1N2Q9", "url": "https://omabrowser.org/oma/group/F1N2Q9/", "database": "OMA" } ], "glygen_name": "Chicken", "common_name": "Chicken" }, { "uniprot_canonical_ac": "G3HIA6-1", "protein_name": "GTP-binding protein Di-Ras2", "gene_name": "Diras2", "tax_id": 10029, "organism": "Cricetulus griseus", "sequence": { "sequence": "MPEQSNDYRVAVFGAGGVGKSSLVLRFVKGTFRESYIPTVEDTYRQVISCDKSICTLQITDTTGSHQFPAMQRLSISKGHAFILVYSITSRQSLEELKPIYEQICEIKGDVDSIPIMLVGNKCDESPNREVQSSEAEALARTWKCAFMETSAKLNHNVKELFQELLNLEKRRTVSLQIDGKKSKQQKRKEKLKGKCVVM", "length": 199 }, "evidence": [ { "id": "F1N2Q9", "url": "https://omabrowser.org/oma/group/F1N2Q9/", "database": "OMA" } ], "glygen_name": "Hamster", "common_name": "Chinese hamster" }, { "uniprot_canonical_ac": "Q5PR73-1", "protein_name": "GTP-binding protein Di-Ras2", "gene_name": "Diras2", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MPEQSNDYRVAVFGAGGVGKSSLVLRFVKGTFRESYIPTVEDTYRQVISCDKSICTLQITDTTGSHQFPAMQRLSISKGHAFILVYSITSRQSLEELKPIYEQICEIKGDVESIPIMLVGNKCDESPNREVQSSEAEALARTWKCAFMETSAKLNHNVKELFQELLNLEKRRTVSLQIDGKKSKQQKRKEKLKGKCVVM", "length": 199 }, "evidence": [ { "id": "F1N2Q9", "url": "https://omabrowser.org/oma/group/F1N2Q9/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q96HU8-1", "protein_name": "GTP-binding protein Di-Ras2", "gene_name": "DIRAS2", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MPEQSNDYRVAVFGAGGVGKSSLVLRFVKGTFRESYIPTVEDTYRQVISCDKSICTLQITDTTGSHQFPAMQRLSISKGHAFILVYSITSRQSLEELKPIYEQICEIKGDVESIPIMLVGNKCDESPSREVQSSEAEALARTWKCAFMETSAKLNHNVKELFQELLNLEKRRTVSLQIDGKKSKQQKRKEKLKGKCVIM", "length": 199 }, "evidence": [ { "id": "F1N2Q9", "url": "https://omabrowser.org/oma/group/F1N2Q9/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "Q9VH66-1", "protein_name": "GTP-binding protein Di-Ras2", "gene_name": "Dmel\\CG8500", "tax_id": 7227, "organism": "Drosophila melanogaster", "sequence": { "sequence": "MTEQKNQVTRAAPEQSNDYRVVVFGAGGVGKSSLVLRFIKGTFRESYIPTIEDTYRQVISCNKNICTLQITDTTGSHQFPAMQRLSISKGHAFILVYSVCSKQSLEELRPIWALIKELKGADIPNIPVMLVGNKCDETAELREVSQAEGQAQATTWSISFMETSAKTNHNVTELFQELLNMEKTRTVSLQLDTKKQKKQKKEKKSKDTNGSIPENGDAGASASGGAKEKCRVM", "length": 233 }, "evidence": [ { "id": "F1N2Q9", "url": "https://omabrowser.org/oma/group/F1N2Q9/", "database": "OMA" } ], "glygen_name": "Fruit fly", "common_name": "Fruit fly" } ], "go_annotation": { "categories": [ { "name": "Molecular Function", "total": 2, "go_terms": [ { "name": "GTPase activity", "id": "GO:0003924", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003924", "evidence": [ { "database": "UniProtKB", "id": "F1N2Q9", "url": "https://www.uniprot.org/uniprotkb/F1N2Q9" } ], "pmid": "" }, { "name": "GTP binding", "id": "GO:0005525", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005525", "evidence": [ { "database": "UniProtKB", "id": "F1N2Q9", "url": "https://www.uniprot.org/uniprotkb/F1N2Q9" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 1, "go_terms": [ { "name": "plasma membrane", "id": "GO:0005886", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005886", "evidence": [ { "database": "UniProtKB", "id": "F1N2Q9", "url": "https://www.uniprot.org/uniprotkb/F1N2Q9" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 1, "go_terms": [ { "name": "small GTPase-mediated signal transduction", "id": "GO:0007264", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007264", "evidence": [ { "database": "UniProtKB", "id": "F1N2Q9", "url": "https://www.uniprot.org/uniprotkb/F1N2Q9" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "homologset.oma", "label": "OMA Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ], "tool_support": { "graph_view": "yes" } }, { "uniprot_canonical_ac": "F1N2Z0-1", "uniprot_ac": "F1N2Z0", "uniprot_id": "F1N2Z0_BOVIN", "mass": { "chemical_mass": 39844.0, "monoisotopic_mass": 39844.0 }, "refseq": {}, "gene_names": [ { "name": "LOC523510", "type": "recommended", "evidence": [ { "id": "F1N2Z0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1N2Z0" } ] } ], "protein_names": [ { "name": "Enoyl reductase (ER) domain-containing protein", "type": "recommended", "evidence": [ { "id": "F1N2Z0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1N2Z0/entry#names_and_taxonomy" } ] } ], "function": [], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Bos taurus", "taxid": 9913, "evidence": [ { "database": "UniProtKB", "id": "F1N2Z0", "url": "https://www.uniprot.org/uniprotkb/F1N2Z0" } ], "common_name": "Bovine", "glygen_name": "Bovine", "reference_species": "Bos taurus [9913]" } ], "gene": [ { "name": "LOC523510", "url": "https://www.uniprot.org/uniprotkb/F1N2Z0", "locus": {} } ], "crossref": [ { "id": "F1N2Z0", "url": "https://alphafold.ebi.ac.uk/entry/F1N2Z0", "database": "AlphaFoldDB", "categories": [] }, { "id": "ENSBTAG00000006986", "url": "https://bgee.org/?page=gene&gene_id=ENSBTAG00000006986", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "IPR002328", "url": "https://www.ebi.ac.uk/interpro/entry/IPR002328", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR011032", "url": "https://www.ebi.ac.uk/interpro/entry/IPR011032", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR013149", "url": "https://www.ebi.ac.uk/interpro/entry/IPR013149", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR013154", "url": "https://www.ebi.ac.uk/interpro/entry/IPR013154", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR020843", "url": "https://www.ebi.ac.uk/interpro/entry/IPR020843", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR036291", "url": "https://www.ebi.ac.uk/interpro/entry/IPR036291", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "PMCTEYK", "url": "https://omabrowser.org/oma/group/PMCTEYK/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "F1N2Z0", "url": "https://www.orthodb.org/?gene=F1N2Z0", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR43880", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR43880", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR43880:SF6", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR43880:SF6", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00107", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00107", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF08240", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF08240", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "F1N2Z0", "url": "https://www.uniprot.org/uniprotkb/F1N2Z0", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "F1N2Z0-1", "url": "https://www.uniprot.org/uniprotkb/F1N2Z0-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MDSLGKTITCLAAIAWKTNSSLSLEEVQVEPPKAGEVRIKMISTGICGSDDHAIKGIIPLKYPFIPGHEGAGLVESIGEGVSSVKPGDKVLTLIVPQCRECSACLNPKGNFCEKQDILPSSGLMLDGTSRFTCKGEKIYHSFRTSTFSEYTVVPEISVVKIDAAAPMDKICVISCEVPTGYGAAVHSAKVTPGSTCVVFGLGGIGSAIVMGCKASGASRIIGVDINEEKFPRARALGVTDCLNPSNLKKPVQEAVKEMTGTGVDFAFEAIGLAETMVAAWDSCHVSHGVCIITGVSPPNSKFSLSAQTVSTGRTLKGVCLGDYKTKDCFPQLVTAYLQNKINIDPLITHQLPFDQLHKAFKLYHAGKTIRCVLLF", "length": 375, "header": "tr|F1N2Z0-1|F1N2Z0_BOVIN Isoform 1 of Enoyl reductase (ER) domain-containing protein OS=Bos taurus OX=9913 GN=LOC523510 PE=3 SV=1 CANONICAL=F1N2Z0-1" }, "isoforms": [ { "isoform_ac": "F1N2Z0-1", "url": "https://www.uniprot.org/uniprotkb/F1N2Z0/entry", "sequence": { "sequence": "MDSLGKTITCLAAIAWKTNSSLSLEEVQVEPPKAGEVRIKMISTGICGSDDHAIKGIIPLKYPFIPGHEGAGLVESIGEGVSSVKPGDKVLTLIVPQCRECSACLNPKGNFCEKQDILPSSGLMLDGTSRFTCKGEKIYHSFRTSTFSEYTVVPEISVVKIDAAAPMDKICVISCEVPTGYGAAVHSAKVTPGSTCVVFGLGGIGSAIVMGCKASGASRIIGVDINEEKFPRARALGVTDCLNPSNLKKPVQEAVKEMTGTGVDFAFEAIGLAETMVAAWDSCHVSHGVCIITGVSPPNSKFSLSAQTVSTGRTLKGVCLGDYKTKDCFPQLVTAYLQNKINIDPLITHQLPFDQLHKAFKLYHAGKTIRCVLLF", "length": 375, "header": "tr|F1N2Z0-1|F1N2Z0_BOVIN Isoform 1 of Enoyl reductase (ER) domain-containing protein OS=Bos taurus OX=9913 GN=LOC523510 PE=3 SV=1 CANONICAL=F1N2Z0-1" }, "locus": { "chromosome": "6", "start_pos": 25341696, "end_pos": 25325361, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000048431.4", "url": "https://www.ensembl.org/id/ENSBTAT00000048431.4" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000045473.3", "url": "https://www.ensembl.org/id/ENSBTAP00000045473.3" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [], "orthologs": [ { "uniprot_canonical_ac": "A0A061IHT8-1", "protein_name": "Alcohol dehydrogenase 1 isoform X2", "gene_name": "LOC100766767", "tax_id": 10029, "organism": "Cricetulus griseus", "sequence": { "sequence": "MDTTGKTITCRAAIAWKEKSPLSIEEVQVEPPKPGEVRVKMASSGICGSDNHVLKGDLSMKFPLIPGHEGAGTVESVGDGVSSVKPGDKVLTLIIPQCRECDACLHSQGNFCDKQDVLPCSGVMLDGTSRFSCRGRKVYHSFRTSTFTEYTVVPEIAVVKIDDAAPMDKVCLLSCGVPTGYGAAVNSAKVTPGSTCVVFGLGGVGSAIVMGCKASGASRIIGVDINEQKFPRARALGVTDCLNPDKLKKSVHEVVMEMTGVGADFAFEAIGNVDTMVSAWNSCNNSYGVCLIIGLAPADTQLTLEAAKIVSGKTLKGVCLGDYKTRDCIPQLVTDYLQDKINIDPLVTHQLPFKQLHKALELYHSGKTVRCVLLF", "length": 375 }, "evidence": [ { "id": "F1N2Z0", "url": "https://omabrowser.org/oma/group/F1N2Z0/", "database": "OMA" } ], "glygen_name": "Hamster", "common_name": "Chinese hamster" }, { "uniprot_canonical_ac": "D3ZT84-1", "protein_name": "Alcohol dehydrogenase 6A (class V)", "gene_name": "Adh6a", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MDTLGKTITCRAAIAWAENSPLSIEEVQVEPPKSGEVRIKMISSGICGSDDHMLKGELLANFPLIPGHEGAGIVESVGDGVCSVKPGDKVLTLIIPQCRECDSCLHLKGNFCEKQDVLPCSGVMLDGTSRFSCRGRKIYHSFRTSSFTEYTVVPEIAVVKIDDAAPMDKVCLISCGFPTGYGAAVNSAKVTPGSTCVVFGLGGVGSAIVMGCKASGASRIIGVDINEQKFPRARALGVTDCLNPKKLEKPVQEVVKEMTGVGVDFAFEAIGQVDTMAAAWNSCNHSYGVCLIVGLAPSDTHLSLEASKILSGKTLKGVCLGDYKTRDCIPQIVTDYLQNKINIDPLVTHQLPFSQLHKALELYHSGKTIRCVLLF", "length": 375 }, "evidence": [ { "id": "F1N2Z0", "url": "https://omabrowser.org/oma/group/F1N2Z0/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "E9Q5Z6-1", "protein_name": "Alcohol dehydrogenase 6A (class V)", "gene_name": "Adh6a", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MNTLGKTITCRAAIAWAKNSPLSIEEVQVEPPKSGEVRIKMISSGICGSDDHVLKGELVVNFPLIPGHEGAGIVESVGDGVCSMKPGDKVLILIIPQCRECDACLHPKGNFCYKQDVLPCSGVMLDGTSRFSCRGQKIYHSFRTSSFTEYTVVPEIAAVKIDDAAPMDKVCLISCGFPTGYGAAVNSAKVTPGSTCVVFGLGGVGSAIVMGCKASGASRIIGVDINEEKFPRARALGVTDCLNPNKLEKPVQEVVMEMTGVGVDFAFEAIGLVDTMVAAWNSCNNSYGVCLIAGLAPSDAQLSLEAPKILSGKTLKGVCLGDYKTRDCIPQIVTDYLQNKINIDPLVTYQLPFNQLHEALELFHSGKAIRCVLLF", "length": 375 }, "evidence": [ { "id": "F1N2Z0", "url": "https://omabrowser.org/oma/group/F1N2Z0/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" } ], "go_annotation": { "categories": [ { "name": "Molecular Function", "total": 2, "go_terms": [ { "name": "zinc ion binding", "id": "GO:0008270", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008270", "evidence": [ { "database": "UniProtKB", "id": "F1N2Z0", "url": "https://www.uniprot.org/uniprotkb/F1N2Z0" } ], "pmid": "" }, { "name": "oxidoreductase activity", "id": "GO:0016491", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016491", "evidence": [ { "database": "UniProtKB", "id": "F1N2Z0", "url": "https://www.uniprot.org/uniprotkb/F1N2Z0" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 19, "end_pos": 21, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [ { "pdb_id": "AF-F1N2Z0-F1", "pdb_chain": "global", "start_pos": 1, "end_pos": 375, "overlap": "1.0", "method": "AlphaFold", "type": "alphafold", "resolution": -1.0, "url": "https://data.glygen.org/ln2downloads/pdb/current/AF-F1N2Z0-F1.pdb", "url_external": "https://alphafold.ebi.ac.uk/entry/F1N2Z0" } ], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "F1N2Z0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1N2Z0" }, { "id": "SM00829", "database": "SMART", "url": "http://smart.embl.de/smart/do_annotation.pl?DOMAIN=SM00829" } ], "ann_type": 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{ "name": "GARIN1A", "type": "recommended", "evidence": [ { "id": "F1N304", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1N304" } ] }, { "name": "FAM71F2", "type": "synonym", "evidence": [ { "id": "NP_001039932", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001039932" } ] }, { "name": "GARIN1A", "type": "synonym", "evidence": [ { "id": "NP_001039932", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001039932" } ] } ], "protein_names": [ { "name": "Golgi associated RAB2 interactor 1A", "type": "synonym", "evidence": [ { "id": "F1N304", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1N304/entry#names_and_taxonomy" } ] }, { "name": "Golgi-associated RAB2 interactor protein 1A", "type": "synonym", "evidence": [ { "id": "NP_001039932", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001039932" } ] }, { "name": "family with sequence similarity 71 member F2", "type": "synonym", "evidence": [ { "id": "NP_001039932", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001039932" } ] } ], "function": [], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Bos taurus", "taxid": 9913, "evidence": [ { "database": "UniProtKB", "id": "F1N304", "url": "https://www.uniprot.org/uniprotkb/F1N304" } ], "common_name": "Bovine", "glygen_name": "Bovine", "reference_species": "Bos taurus [9913]" } ], "gene": [ { "name": "GARIN1A", "url": "https://www.uniprot.org/uniprotkb/F1N304", "locus": { "chromosome": "4", "start_pos": 92674004, "end_pos": 92662571, "strand": "-", "evidence": [ { "database": "Ensembl Gene", "id": "ENSBTAG00000024291", "url": "https://www.ensembl.org/id/ENSBTAG00000024291" } ] } } ], "crossref": [ { "id": "F1N304", "url": "https://alphafold.ebi.ac.uk/entry/F1N304", "database": "AlphaFoldDB", "categories": [] }, { "id": "ENSBTAG00000024291", "url": "https://bgee.org/?page=gene&gene_id=ENSBTAG00000024291", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "540061", "url": "https://www.ncbi.nlm.nih.gov/gene/540061", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR022168", "url": "https://www.ebi.ac.uk/interpro/entry/IPR022168", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR026190", "url": "https://www.ebi.ac.uk/interpro/entry/IPR026190", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "bta:540061", "url": "https://www.genome.jp/dbget-bin/www_bget?bta:540061", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "RIEFTHC", "url": "https://omabrowser.org/oma/group/RIEFTHC/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "F1N304", "url": "https://www.orthodb.org/?gene=F1N304", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR22574", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR22574", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR22574:SF10", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR22574:SF10", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF12480", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF12480", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF15220", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF15220", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "NP_001039932", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001039932", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0ABI0P660", "url": "https://www.uniprot.org/uniprotkb/A0ABI0P660", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0ABI0P660-1", "url": "https://www.uniprot.org/uniprotkb/A0ABI0P660-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "F1N304", "url": "https://www.uniprot.org/uniprotkb/F1N304", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "F1N304-1", "url": "https://www.uniprot.org/uniprotkb/F1N304-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MSKIPGLPPEVREPGPGVELGVEDGLLCQLIHSPEFNLFSDSVVFESIFIQVTKPGNWMDDCEGPTTVILGVTSSVPSLPLPNILLMANVTWPQGQFSTWSTPGSAPVITLSRILPLKYVELRIYDRLQRILRVRTVTEKIYYLRLHEKYPETVFQFWTRLVNILQRGLSITTKDPRIRISHCLVPKLPCRSAETSESSLPSSSRPSESSMLLAAEQNSDRFLNLSGTSQLTVHRNTNSATEIETFNCKDNTSSPASSPVISNIPMRAALSHSLWEQENADEYHIQAPVASSLGENFWGP", "length": 300, "header": "tr|F1N304-1|F1N304_BOVIN Isoform 1 of Golgi associated RAB2 interactor 1A OS=Bos taurus OX=9913 GN=GARIN1A PE=3 SV=1 CANONICAL=F1N304-1" }, "isoforms": [ { "isoform_ac": "A0ABI0P660-1", "url": "https://www.uniprot.org/uniprotkb/A0ABI0P660/entry", "sequence": { "sequence": 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"MSKIPGLPPEVREPGPGVELGVEDGLLCQLIHSPEFNLFSDSVVFESIFIQVTKPGNWMDDCEGPTTVILGVTSSVPSLPLPNILLMANVTWPQGQFSTWSTPGSAPVITLSRILPLKYVELRIYDRLQRILRVRTVTEKIYYLRLHEKYPETVFQFWTRLVNILQRGLSITTKDPRIRISHCLVPKLPCRSAETSESSLPSSSRPSESSMLLAAEQNSDRFLNLSGTSQLTVHRNTNSATEIETFNCKDNTSSPASSPVISNIPMRAALSHSLWEQENADEYHIQAPVASSLGENFWGP", "length": 300, "header": "tr|F1N304-1|F1N304_BOVIN Isoform 1 of Golgi associated RAB2 interactor 1A OS=Bos taurus OX=9913 GN=GARIN1A PE=3 SV=1 CANONICAL=F1N304-1" }, "locus": { "chromosome": "4", "start_pos": 92673848, "end_pos": 92662661, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000033556.5", "url": "https://www.ensembl.org/id/ENSBTAT00000033556.5" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000033468.3", "url": "https://www.ensembl.org/id/ENSBTAP00000033468.3" } ] } } ], "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "other", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 102, "start_aa": "Thr", "end_pos": 102, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr102", "evidence": [ { "id": "", "database": "GlyGen", "url": "https://data.glygen.org/" } ], "filter_code": "000000000000000010000.00000000001000.0.01000" }, { "glytoucan_ac": "", "type": "O-linked", "subtype": "other", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 66, "start_aa": "Thr", "end_pos": 66, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr66", "evidence": [ { "id": "", "database": "GlyGen", "url": "https://data.glygen.org/" } ], "filter_code": "000000000000000010000.00000000001000.0.01000" } ], "phosphorylation": [], "glycation": [], "keywords": [ "glycoprotein", "glycoprotein_predicted" ], "publication": [], "pathway": [ { "id": "bta:540061", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?bta:540061", "resource": "KEGG Pathway" } ], "orthologs": [ { "uniprot_canonical_ac": "B2RXB0-1", "protein_name": "Golgi-associated RAB2 interactor protein 1A", "gene_name": "Garin1a", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MSKIRGLPPAIRDPGPGVELGVVDGLLCQLIHSPEFNLFSDSVVFESTFIQVTKQGNWMDAYERSATMILGVTSSVPSLPLPNILLMANVTWPHGPFSTCSTLGAPVITLSRILPLKYVELQIYDRTQRILRVRTVTEKIYYLRLHEKHPQAVFQFWIRLVKILQKGLSITTKDPRIQFTHCLVPKMSNSSTETATESSLPASSQNSEAIMLLAAERNSSSLLELSNRHQTSRDRHTDTATETDNSGNCKSTPLVASSASMPMRAALTHSLWEQEDSNENFLQAPVASSLGENLLGP", "length": 297 }, "evidence": [ { "id": "F1N304", "url": "https://omabrowser.org/oma/group/F1N304/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "F1SMM8-1", "protein_name": "Golgi associated RAB2 interactor 1A", "gene_name": "GARIN1A", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MSKIRGLPPEVREPGPGVELGVEDGLLCQLIHSPEFNLFSNSAVFESNFIQVTKPGNWMDVCERSTTVILGVTSSVPSLPLPNILLMANVTWPQGQFSTWSVPGCAPVVTLSRILPLKYVELRICDRLQRILRVRTVTEKIYYLRLHEKHPEAVFQFWIRLVKILQRGLSITTKDRRIQFSHCLVPKLPSSTETSAGSLPSSRQPSESTMLLAAEQTSDPFSNLSGKSQLTADRNTNTAIEIDNSNSFDKTPSPVASPVISNIPMRATLSHSLWEQENPDEHFLQAPVASSLGENFLGP", "length": 299 }, "evidence": [ { "id": "F1N304", "url": "https://omabrowser.org/oma/group/F1N304/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "Q5RJN7-1", "protein_name": "Golgi-associated RAB2 interactor protein 1A", "gene_name": "Garin1a", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MSKIRGLPPAIRDPGPGVELGVENGLLCQLIHSPEFNLFSDSVVFESTFIQVTKQGNWMDAYERSATIILGVTSSVPSLPLPNILLMANVTWPQGPFSTCSTLGAPVITLSRILPLKYVELQIYDRTQRILRVRTVTEKIYYLRLHEKHPQAVFRFWIRLVKILQKGLSITTKDPRIHFTHCLVPKMPNSSTETTPESSRPASSQSSETIMLLAAERAGSSVLDLSNRHRFSEDRYTDTKTDNSSNCKTASPVASLIGMPMRATLIHSLWEQEDSCETLLQAPVASSLGDNFLGP", "length": 295 }, "evidence": [ { "id": "F1N304", "url": "https://omabrowser.org/oma/group/F1N304/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "Q6NXP2-1", "protein_name": "Golgi-associated RAB2 interactor protein 1A", "gene_name": "GARIN1A", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MSKIRGLPPEVREPGPGVELGVENGLLCQLIHSPEFNLFSNSVVFESNFIQTHVPEADFQVTKPGNWRDVCEGSATVILGVTSSVPSLPLPNVLLMANVTWPQGPFTTWSTPGDAPVINLSRLLPLKYVELRIYDRLQRILRVRTVTEKIYYLKLHEKHPEIVFQFWVRLVKILQKGLSITTKDPRIKFTHCLVPKMPTNSTETTPENSLLSSPQPSEPLVLLAAEQTSGSFSQLSGKPQLTADRNNDTAIEIDNCSSYKIPSPVASPINLNIPMRAALSHSLWEQEDWNEHLLQVHIASYLGEHFLGA", "length": 309 }, 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CANONICAL=F1N325-1" }, "locus": { "chromosome": "16", "start_pos": 51316010, "end_pos": 51301206, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000034047.6", "url": "https://www.ensembl.org/id/ENSBTAT00000034047.6" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000033949.6", "url": "https://www.ensembl.org/id/ENSBTAP00000033949.6" } ] } } ], "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "other", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 147, "start_aa": "Thr", "end_pos": 147, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr147", "evidence": [ { "id": "", "database": "GlyGen", "url": "https://data.glygen.org/" } ], "filter_code": "000000000000000010000.00000000001000.0.01000" } ], "phosphorylation": [], "glycation": [], "keywords": [ "glycoprotein", "glycoprotein_predicted" ], "publication": [], "pathway": [ { "id": "bta:100336825", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?bta:100336825", "resource": "KEGG Pathway" } ], "orthologs": [], "go_annotation": { "categories": [ { "name": "Molecular Function", "total": 2, "go_terms": [ { "name": "ATP binding", "id": "GO:0005524", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005524", "evidence": [ { "database": "UniProtKB", "id": "F1N325", "url": "https://www.uniprot.org/uniprotkb/F1N325" } ], "pmid": "" }, { "name": "protein-glycine ligase activity, elongating", "id": "GO:0070737", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0070737", "evidence": [ { "database": "UniProtKB", "id": "F1N325", "url": "https://www.uniprot.org/uniprotkb/F1N325" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 1, "go_terms": [ { "name": "cytoplasm", "id": "GO:0005737", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005737", "evidence": [ { "database": "UniProtKB", "id": "F1N325", "url": "https://www.uniprot.org/uniprotkb/F1N325" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 96, "end_pos": 98, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [ { "pdb_id": "AF-F1N325-F1", "pdb_chain": "global", "start_pos": 1, "end_pos": 755, "overlap": "1.0", "method": "AlphaFold", "type": "alphafold", "resolution": -1.0, "url": "https://data.glygen.org/ln2downloads/pdb/current/AF-F1N325-F1.pdb", "url_external": "https://alphafold.ebi.ac.uk/entry/F1N325" } ], "lectin_list": [], "domain_list": [], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [ 147 ], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 96, "end_pos": 98 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 1 }, { "field": "total_sites", "count": 1 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 1 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "exact_sites", "count": 1 }, { "field": "exact_o_linked_sites", "count": 1 }, { "field": "fuzzy_sites", "count": 0 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_pos", "start_aa", "end_pos", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": 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"MSSKGSSTDGRTDLANGSLSSSPEEMSGAEEGRETSSGIEVEASDLSLSLTGDDGGPNRTSTESRGTDTESSGEDKDSDSMEDTGHYSVNDESQVHDRSEEEEEEEHPRRRVQRKRANRDQDSSDDERALEDWVSSETSALPRPRWQALPALRERELGSSARFVYEACGARVFVQRFRLQHGLEGHTGCVNTLHFNQRGTWLASGSDDLKVVVWDWVRRQPVLDFESGHKSNVFQAKFLPNSGDSTLAMCARDGQVRVAELSATQCCKNTKRVAQHKGASHKLALEPDSPCTFLSAGEDAVVFTIDLRQDRPASKLVVTKEKEKKVGLYTIYVNPANTHQFAVGGRDQFVRIYDQRKIDENENNGVLKKFCPHHLVNSESKANITCLVYSHDGTELLASYNDEDIYLFNSSHSDGAQYIKRYKGHRNNATVKGVNFYGPKSEFVVSGSDCGHIFLWEKSSCQIIQFMEGDKGGVVNCLEPHPHLPVLATSGLDHDVKIWAPTAETSTELTGLKDVIKKNKRERDEDSLHHTDLFDSHMLWFLMHHLRQRRHHRRWREPGVGATDADSDESPSSSDTSDEEEGPDRVQCMPS", "length": 591, "header": "tr|F1N3H0-1|F1N3H0_BOVIN Isoform 1 of DDB1 and CUL4 associated factor 8 OS=Bos taurus OX=9913 GN=DCAF8 PE=3 SV=1 CANONICAL=F1N3H0-1" }, "isoforms": [ { "isoform_ac": "F1N3H0-1", "url": "https://www.uniprot.org/uniprotkb/F1N3H0/entry", "sequence": { "sequence": 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"Ensembl Peptide", "id": "ENSBTAP00000064896.1", "url": "https://www.ensembl.org/id/ENSBTAP00000064896.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [ { "id": "bta:510316", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?bta:510316", "resource": "KEGG Pathway" }, { "id": "R-BTA-8951664", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-BTA-8951664", "resource": "Reactome", "description": "Neddylation" } ], "orthologs": [ { "uniprot_canonical_ac": "A0A8V1AGI1-1", "protein_name": "DDB1 and CUL4 associated factor 8", "gene_name": "DCAF8", "tax_id": 9031, "organism": "Gallus gallus", "sequence": { "sequence": 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"MSSKGSSTDGRTDLANGSLSSSPEEMSGAEEGRETSSGIEVEASDLSLSLTGDDGGPNRTSTESRGTDTESSGEDKDSDSMEDTGHYSINDENRVHDRSEEEEEEEEEEEEEQPRRRVQRKRANRDQDSSDDERALEDWVSSETSALPRPRWQALPALRERELGSSARFVYEACGARVFVQRFRLQHGLEGHTGCVNTLHFNQRGTWLASGSDDLKVVVWDWVRRQPVLDFESGHKSNVFQAKFLPNSGDSTLAMCARDGQVRVAELSATQCCKNTKRVAQHKGASHKLALEPDSPCTFLSAGEDAVVFTIDLRQDRPASKLVVTKEKEKKVGLYTIYVNPANTHQFAVGGRDQFVRIYDQRKIDENENNGVLKKFCPHHLVNSESKANITCLVYSHDGTELLASYNDEDIYLFNSSHSDGAQYVKRYKGHRNNATVKGVNFYGPKSEFVVSGSDCGHIFLWEKSSCQIIQFMEGDKGGVVNCLEPHPHLPVLATSGLDHDVKIWAPTAEASTELTGLKDVIKKNKRERDEDSLHQTDLFDSHMLWFLMHHLRQRRHHRRWREPGVGATDADSDESPSSSDTSDEEEGPDRVQCMPS", "length": 597 }, "evidence": [ { "id": "F1N3H0", "url": "https://omabrowser.org/oma/group/F1N3H0/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "Q5U2M6-1", "protein_name": "DDB1- and CUL4-associated factor 8", "gene_name": "Dcaf8", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": 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"MARPRRRNTEIGDGFTEIFNREIGFSHPITISRRISASEGRVKKLDLYGKLNGHEGCVNAVEFNSTGDVLVSGSDDRQIMLWNWLSGSRKLSYPSGHCENVFQTKFIPFTDDRTIITSGADGQVRLGQILENGKVETKRLGRHHGRVYKLAVLPGDPNVFYSCGEDGFVQHFDIRSNSATMVLYSSPFTQGCRRHHSSSRIRLNSIAIDPRNSYYLAVGGSDEYARVYDTRRVQLAPVCRHVLPDAPVNTFCPRHLRETNSVHITGLAYSKAGELLVSYNDELIYLFEKNMGYGSSPVSVSPEKLQEMEEPQVYIGHRNAQTVKGVNFFGPNDEYVTSGSDCGHIFIWKKKGGKLVRAMVGDRRVVNQLESHPHIPLLASCGIEKSVKLWTPMSNDVLSLPEKIDKVMELNRVGREDQSRVTLTPDVIMHVLRLQRRQTSAFTERRYVSTDIGSDEGNDARFIASLVANDDESSDRECTVS", "length": 481 }, "evidence": [ { "id": "F1N3H0", "url": "https://omabrowser.org/oma/group/F1N3H0/", "database": "OMA" } ], "glygen_name": "Arabidopsis", "common_name": "Mouse-ear cress" } ], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 4, "go_terms": [ { "name": "nucleoplasm", "id": "GO:0005654", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005654", "evidence": [ { "database": "UniProtKB", "id": "F1N3H0", "url": "https://www.uniprot.org/uniprotkb/F1N3H0" } ], "pmid": "" }, { "name": "cytoplasm", "id": "GO:0005737", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005737", "evidence": [ { "database": "UniProtKB", "id": "F1N3H0", "url": "https://www.uniprot.org/uniprotkb/F1N3H0" } ], "pmid": "" }, { "name": "cytosol", "id": "GO:0005829", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005829", "evidence": [ { "database": "UniProtKB", "id": "F1N3H0", "url": "https://www.uniprot.org/uniprotkb/F1N3H0" } ], "pmid": "" }, { "name": "Cul4-RING E3 ubiquitin ligase complex", "id": "GO:0080008", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0080008", "evidence": [ { "database": "UniProtKB", "id": "F1N3H0", "url": "https://www.uniprot.org/uniprotkb/F1N3H0" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 16, "end_pos": 18, "annotation": "n_glycosylation_sequon" }, { "start_pos": 383, "end_pos": 385, "annotation": "n_glycosylation_sequon" }, { "start_pos": 409, "end_pos": 411, "annotation": "n_glycosylation_sequon" }, { "start_pos": 428, "end_pos": 430, "annotation": "n_glycosylation_sequon" }, { "start_pos": 58, "end_pos": 60, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [ { "pdb_id": "AF-F1N3H0-F1", "pdb_chain": "global", "start_pos": 1, "end_pos": 591, "overlap": "1.0", "method": "AlphaFold", "type": "alphafold", "resolution": -1.0, "url": "https://data.glygen.org/ln2downloads/pdb/current/AF-F1N3H0-F1.pdb", "url_external": "https://alphafold.ebi.ac.uk/entry/F1N3H0" } ], "lectin_list": [], "domain_list": [], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "homologset.oma", "label": "OMA Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 16, "end_pos": 18 }, { "start_pos": 383, 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"synonym", "evidence": [ { "id": "F1N3J9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1N3J9/entry#names_and_taxonomy" } ] }, { "name": "opioid growth factor receptor-like protein 1 isoform X1", "type": "synonym", "evidence": [ { "id": "XP_024852645", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_024852645" } ] } ], "function": [], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Bos taurus", "taxid": 9913, "evidence": [ { "database": "UniProtKB", "id": "F1N3J9", "url": "https://www.uniprot.org/uniprotkb/F1N3J9" } ], "common_name": "Bovine", "glygen_name": "Bovine", "reference_species": "Bos taurus [9913]" } ], "gene": [ { "name": "OGFRL1", "url": "https://www.uniprot.org/uniprotkb/F1N3J9", "locus": { "chromosome": "9", "start_pos": 10414051, "end_pos": 10397709, "strand": "-", "evidence": [ { "database": "Ensembl Gene", "id": "ENSBTAG00000016374", "url": "https://www.ensembl.org/id/ENSBTAG00000016374" } ] } } ], "crossref": [ { "id": "F1N3J9", "url": "https://alphafold.ebi.ac.uk/entry/F1N3J9", "database": "AlphaFoldDB", "categories": [] }, { "id": "ENSBTAG00000016374", "url": "https://bgee.org/?page=gene&gene_id=ENSBTAG00000016374", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "519626", "url": "https://www.ncbi.nlm.nih.gov/gene/519626", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR006757", "url": "https://www.ebi.ac.uk/interpro/entry/IPR006757", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR039574", "url": "https://www.ebi.ac.uk/interpro/entry/IPR039574", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "bta:519626", "url": "https://www.genome.jp/dbget-bin/www_bget?bta:519626", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "MHKKPKD", "url": "https://omabrowser.org/oma/group/MHKKPKD/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "F1N3J9", "url": "https://www.orthodb.org/?gene=F1N3J9", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR14015", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR14015", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR14015:SF0", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR14015:SF0", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF04664", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF04664", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "XP_024852645", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_024852645", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "F1N3J9", "url": "https://www.uniprot.org/uniprotkb/F1N3J9", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "F1N3J9-1", "url": "https://www.uniprot.org/uniprotkb/F1N3J9-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MGNLLGGVSVREPTTVEDCDSTWQTDSEPELEEPGPGGGEGPGREPAQPPEPAEPAEPPERAGGRLRAGPAPEPDPEAAGAEQGTDSTEAPAKPKRSFYAARDLYKYRHQYPQNFKDIRYQNDLSNLRFYKNKIPFKPDGVYIEEVLNKWKGDYEKLEHNHTYIQWLFPLREQGLNFYAKELTTYEIEEFKKTKEAIRRFLLAYKMMLEFFGIKLIDKTGNVARAVNWQERFQHLNESQHNYLRITRILKSLGELGYESFKSPLVKFILHEALVENTIPNIKQSALEYFVYTIRDRRERRKLLRFAQKHYTPSENFIWGPPRKAQPEGSKAQKPPGPPTAGQHGQMSMHKKPKDSKNASSAAHGISKAAEDKKVASKESEEMDKPSEEPGSEAAQPGDPGQDEVANNSSPRAAKTVTHPEEQKESASPSEKDEASDTRNQDGGSPGDAGSHDDAALP", "length": 457, "header": "tr|F1N3J9-1|F1N3J9_BOVIN Isoform 1 of Opioid growth factor receptor like 1 OS=Bos taurus OX=9913 GN=OGFRL1 PE=3 SV=2 CANONICAL=F1N3J9-1" }, "isoforms": [ { "isoform_ac": "F1N3J9-1", "url": "https://www.uniprot.org/uniprotkb/F1N3J9/entry", "sequence": { "sequence": "MGNLLGGVSVREPTTVEDCDSTWQTDSEPELEEPGPGGGEGPGREPAQPPEPAEPAEPPERAGGRLRAGPAPEPDPEAAGAEQGTDSTEAPAKPKRSFYAARDLYKYRHQYPQNFKDIRYQNDLSNLRFYKNKIPFKPDGVYIEEVLNKWKGDYEKLEHNHTYIQWLFPLREQGLNFYAKELTTYEIEEFKKTKEAIRRFLLAYKMMLEFFGIKLIDKTGNVARAVNWQERFQHLNESQHNYLRITRILKSLGELGYESFKSPLVKFILHEALVENTIPNIKQSALEYFVYTIRDRRERRKLLRFAQKHYTPSENFIWGPPRKAQPEGSKAQKPPGPPTAGQHGQMSMHKKPKDSKNASSAAHGISKAAEDKKVASKESEEMDKPSEEPGSEAAQPGDPGQDEVANNSSPRAAKTVTHPEEQKESASPSEKDEASDTRNQDGGSPGDAGSHDDAALP", "length": 457, "header": "tr|F1N3J9-1|F1N3J9_BOVIN Isoform 1 of Opioid growth factor receptor like 1 OS=Bos taurus OX=9913 GN=OGFRL1 PE=3 SV=2 CANONICAL=F1N3J9-1" }, "locus": { "chromosome": "9", "start_pos": 10413047, "end_pos": 10397908, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000021778.6", "url": "https://www.ensembl.org/id/ENSBTAT00000021778.6" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000021778.5", "url": "https://www.ensembl.org/id/ENSBTAP00000021778.5" } ] } } ], "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "other", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 339, "start_aa": "Thr", "end_pos": 339, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr339", "evidence": [ { "id": "", "database": "GlyGen", "url": "https://data.glygen.org/" } ], "filter_code": "000000000000000010000.00000000001000.0.01000" } ], "phosphorylation": [], "glycation": [], "keywords": [ "glycoprotein", "glycoprotein_predicted" ], "publication": [], "pathway": [ { "id": "bta:519626", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?bta:519626", "resource": "KEGG Pathway" } ], "orthologs": [ { "uniprot_canonical_ac": "A0A8V0XD65-1", "protein_name": "Opioid growth factor receptor like 1", "gene_name": "OGFRL1", "tax_id": 9031, "organism": "Gallus gallus", "sequence": { "sequence": "MVEEPECWGRRGREAWHPPAVSWGPSAAVARLALTQRTAALLGHQCRRSLPRMQSGPTGVGFLAYKLPLCKIKQVLAFIVSFLLDARYWWLADACVSGCCLLSDGTELTAKPKRSFYAARDLYKYRHQYPQNFKDLRYQNDLCNLRFYKNKIPFKPDGVYIEEVLNKWKGDYEKLEHNHTYIQWLFPLREQGLNFYAKELTTYEIEEFKKTKEAIRRFLLAYKMMLEFFGIKLIDKTGNVARAANWQERFQHLNESQHNYLRITRILKSLGELGYESFKSPLVKFILHEALVEDTIPNIKQSALEYFVYTIRDRRERRKLLRFAQQHYSPSEHFIWGPPRKQKSEGSKTNKKPASPISIHSSYISKHKKLKEPKSTSTSGTSASKATEERKVEITKNGEENDQDEQEMNCDAVKQSSEKNSSTDTGQLSKSEEIHDPSDKKEDASQSKKDDENMDNDCGNHPGVIDISLCDTENCSNNVSSDLQDSLDKDSPSGGTTTKTKDEIKL", "length": 506 }, "evidence": [ { "id": "F1N3J9", "url": "https://omabrowser.org/oma/group/F1N3J9/", "database": "OMA" } ], "glygen_name": "Chicken", "common_name": "Chicken" }, { "uniprot_canonical_ac": "E7EYE2-1", "protein_name": "Opioid growth factor receptor-like protein 1", "gene_name": "ogfrl1", "tax_id": 7955, "organism": "Danio rerio", "sequence": { "sequence": 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"MGNLLGGVSFREPTTVEDCDSTWQTDSEPEPEQPGPAGGGEGQEQDEREQPEQPPERAGGRPRASPVPEDHAEAAGAEQGGDSTEGNAKPKRSFYAARDLYKYRHQYPNFKDIRYQNDLSNLRFYKNKIPFKPDGVYIEEVLNKWKGDYEKLEHNHTYIQWLFPLREQGLNFYAKELTTYEIEEFKKTKEAIRRFLLAYKMMLEFFGIKLIDKTGNVARAVNWQERFQHLNESQHNYLRITRILKSLGELGYESFKSPLVKFILHEALVENTIPNIKQSALEYFVYTIRDRRERRKLLRFAQKHYTPSENFIWGPPKKEQPERSKAQKTPTLPALGSNGQTSTHKKSKDSKNSSAASHLNNKTVEEKKVASREPGEETDKPSPEASSEDTKPRNSEDDNAADQSESPPKKTVNDSAGKGECPTTSSEKDGEGENQSKDSENPENTSCHAEVVSQQNVTNPQTSSG", "length": 465 }, "evidence": [ { "id": "F1N3J9", "url": "https://omabrowser.org/oma/group/F1N3J9/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "Q5TC84-1", "protein_name": "Opioid growth factor receptor-like protein 1", "gene_name": "OGFRL1", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MGNLLGGVSFREPTTVEDCDSTWQTDSEPEPEEPGPGGGSEGPGQESEQPAQPPEQAGGRPGASPAPDEDAEAAGAEQGGDSTEATAKPKRSFYAARDLYKYRHQYPNFKDIRYQNDLSNLRFYKNKIPFKPDGVYIEEVLSKWKGDYEKLEHNHTYIQWLFPLREQGLNFYAKELTTYEIEEFKKTKEAIRRFLLAYKMMLEFFGIKLTDKTGNVARAVNWQERFQHLNESQHNYLRITRILKSLGELGYESFKSPLVKFILHEALVENTIPNIKQSALEYFVYTIRDRRERRKLLRFAQKHYTPSENFIWGPPRKEQSEGSKAQKMSSPLASSHNSQTSMHKKAKDSKNSSSAVHLNSKTAEDKKVAPKEPVEETDRPSPEPSNEAAKPRNTEKDSNAENMNSQPEKTVTTPTEKKESVSPENNEEGGNDNQDNENPGNTNCHDVVLVQ", "length": 451 }, "evidence": [ { "id": "F1N3J9", "url": "https://omabrowser.org/oma/group/F1N3J9/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "Q8VE52-1", "protein_name": "Opioid growth factor receptor-like protein 1", "gene_name": "Ogfrl1", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MGNLLGGVSFREPTTVEDCDSTWQTDSEPEPEQPGPAGGGEGQQHDEPEQPKQPPERAGGRPRASPVPEDHAEAAGAEQGGESTEGNAKPKRSFYAARDLYKYRHQYPNFKDIRYQNDLSNLRFYKNKIPFKPDGVYIEEVLNKWKGDYEKLEHNHTYIQWLFPLREQGLNFYAKELTTYEIEEFKKTKEAIRRFLLAYKMMLEFFGIKLIDKTGNVARAGNWQERFQHLNESQHNYLRITRILKSLGELGYESFKSPLVKFILHEALVENTIPNIKQSALEYFVYTIRDRRERRKLLRFAQKHYTPSENFIWGPPKKELPERSKAQKTPTLPASGSNGQTSTHKKSKDSKISPGASHVNSKSVEEKKGASREPGEEADKPSPEPGSGDPKPRNTEKDSAADQSDSPPEKTVPDTAGKGECPTSSEKDGEGEDQSKDSENPENAGCHAEVVAQQNATNPQTSSG", "length": 464 }, "evidence": [ { "id": "F1N3J9", "url": "https://omabrowser.org/oma/group/F1N3J9/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" } ], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 1, "go_terms": [ { "name": "membrane", "id": "GO:0016020", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016020", "evidence": [ { "database": "UniProtKB", "id": "F1N3J9", "url": "https://www.uniprot.org/uniprotkb/F1N3J9" } ], "pmid": "" } ] }, { "name": "Molecular Function", "total": 1, "go_terms": [ { "name": "opioid growth factor receptor activity", "id": "GO:0140625", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0140625", "evidence": [ { "database": "UniProtKB", "id": "F1N3J9", "url": "https://www.uniprot.org/uniprotkb/F1N3J9" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 160, "end_pos": 162, "annotation": "n_glycosylation_sequon" }, { "start_pos": 236, "end_pos": 238, "annotation": "n_glycosylation_sequon" }, { "start_pos": 357, "end_pos": 359, "annotation": "n_glycosylation_sequon" }, { "start_pos": 406, "end_pos": 408, "annotation": "n_glycosylation_sequon" }, { "start_pos": 407, "end_pos": 409, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [ { "pdb_id": "AF-F1N3J9-F1", "pdb_chain": "global", "start_pos": 1, "end_pos": 457, "overlap": "1.0", "method": "AlphaFold", "type": 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"end_pos": 162 }, { "start_pos": 236, "end_pos": 238 }, { "start_pos": 357, "end_pos": 359 }, { "start_pos": 406, "end_pos": 408 }, { "start_pos": 407, "end_pos": 409 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 1 }, { "field": "total_sites", "count": 1 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 1 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "exact_sites", "count": 1 }, { "field": "exact_o_linked_sites", "count": 1 }, { "field": "fuzzy_sites", "count": 0 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_pos", "start_aa", "end_pos", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", 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"count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ], "tool_support": { "graph_view": "yes" } }, { "uniprot_canonical_ac": "F1N3R0-1", "uniprot_ac": "F1N3R0", "uniprot_id": "F1N3R0_BOVIN", "mass": { "chemical_mass": 46258.0, "monoisotopic_mass": 46258.0 }, "refseq": {}, "gene_names": [ { "name": "SCRN2", "type": "recommended", "evidence": [ { "id": "F1N3R0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1N3R0" } ] } ], "protein_names": [ { "name": "Secernin-2", "type": "recommended", "evidence": [ { "id": "F1N3R0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1N3R0/entry#names_and_taxonomy" } ] } ], "function": [], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Bos taurus", "taxid": 9913, "evidence": [ { "database": "UniProtKB", "id": "F1N3R0", "url": "https://www.uniprot.org/uniprotkb/F1N3R0" } ], "common_name": "Bovine", "glygen_name": "Bovine", "reference_species": "Bos taurus [9913]" } ], "gene": [ { "name": "SCRN2", "url": "https://www.uniprot.org/uniprotkb/F1N3R0", "locus": { "chromosome": "19", "start_pos": 38626909, "end_pos": 38623604, "strand": "-", "evidence": [ { "database": "Ensembl Gene", "id": "ENSBTAG00000001828", "url": "https://www.ensembl.org/id/ENSBTAG00000001828" } ] } } ], "crossref": [ { "id": "F1N3R0", "url": "https://alphafold.ebi.ac.uk/entry/F1N3R0", "database": "AlphaFoldDB", "categories": [] }, { "id": "ENSBTAG00000001828", "url": "https://bgee.org/?page=gene&gene_id=ENSBTAG00000001828", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "IPR005322", "url": "https://www.ebi.ac.uk/interpro/entry/IPR005322", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "F1N3R0", "url": "https://www.orthodb.org/?gene=F1N3R0", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR12994", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR12994", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR12994:SF16", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR12994:SF16", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF03577", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF03577", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "A0ABI0NK04", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NK04", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0ABI0NK04-1", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NK04-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "F1N3R0", "url": "https://www.uniprot.org/uniprotkb/F1N3R0", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "F1N3R0-1", "url": "https://www.uniprot.org/uniprotkb/F1N3R0-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MASWSPDTPCSCDCFVSVPPASALPAVIFAKNSDRPRDEVQEVVFVPAGTHAPGSRLQCTYIEVEQVSKTHAVILSRPSWLWGAEMGANEHGVCIGNEAVWTKEPVGEGEALLGMDLLRLALERGSSAREALHVITGLLERYGQGGSCREDPTPFCYHNTFLLADRTEAWVLETAGRLWAARRIQEGVHNISNQLSIGSDISAEHPELRPHAQVQGWWDGQGTFDFAQVFSLSQQPVRMEAAKARFRAGQELLQQQQGGITAEVMMGILRDKESGICMDSGGFRTTASMVSVLPRDTTQPCVHFLTATPDPSRSVFKPFIFGVGAAQPPQVLSPTFGAQDPVRTLPRFQTQVDRRHPLYRGHQVALGLMESEQLRQKQRDLEQEGLVAVRRLLTRECAPPAQELGGLFQAFVEKETQAYS", "length": 420, "header": "tr|F1N3R0-1|F1N3R0_BOVIN Isoform 1 of Secernin-2 OS=Bos taurus OX=9913 GN=SCRN2 PE=3 SV=3 CANONICAL=F1N3R0-1" }, "isoforms": [ { "isoform_ac": "A0ABI0NK04-1", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NK04/entry", "sequence": { "sequence": "MASWSPDTPCSCDCFVSVPPASALPAVIFAKNSDRPRDEVQEVVFVPAGTHAPGSRLQCTYIEVEQVSKTHAVILSRPSWLWGAEMGANEHGVCIGNEAVWTKEPVGEGEALLGMDLLRVVLFSSPLCSQHLAECLAQDRGSTIYERPLISSVEGVHNISNQLSIGSDISAEHPELRPHAQVQGWWDGQGTFDFAQVFSLSQQPVRMEAAKARFRAGQELLQQQQGGITAEVMMGILRDKESGICMDSGGFRTTASMVSVLPRDTTQPCVHFLTATPDPSRSVFKPFIFGVGAAQPPQVLSPTFGAQDPVRTLPRFQTQVDRRHPLYRGHQVALGLMESEQARGQQLRQKQRDLEQEGLVAVRRLLTRECAPPAQELGGLFQAFVEKETQAYS", "length": 393, "header": "tr|A0ABI0NK04-1|A0ABI0NK04_BOVIN Computationally mapped isoform of Secernin-2 OS=Bos taurus OX=9913 GN=SCRN2 PE=3 SV=1 CANONICAL=F1N3R0-1" }, "locus": { "chromosome": "19", "start_pos": 38626700, "end_pos": 38623604, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000150645.1", "url": "https://www.ensembl.org/id/ENSBTAT00000150645.1" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000104609.1", "url": "https://www.ensembl.org/id/ENSBTAP00000104609.1" } ] } }, { "isoform_ac": "F1N3R0-1", "url": "https://www.uniprot.org/uniprotkb/F1N3R0/entry", "sequence": { "sequence": "MASWSPDTPCSCDCFVSVPPASALPAVIFAKNSDRPRDEVQEVVFVPAGTHAPGSRLQCTYIEVEQVSKTHAVILSRPSWLWGAEMGANEHGVCIGNEAVWTKEPVGEGEALLGMDLLRLALERGSSAREALHVITGLLERYGQGGSCREDPTPFCYHNTFLLADRTEAWVLETAGRLWAARRIQEGVHNISNQLSIGSDISAEHPELRPHAQVQGWWDGQGTFDFAQVFSLSQQPVRMEAAKARFRAGQELLQQQQGGITAEVMMGILRDKESGICMDSGGFRTTASMVSVLPRDTTQPCVHFLTATPDPSRSVFKPFIFGVGAAQPPQVLSPTFGAQDPVRTLPRFQTQVDRRHPLYRGHQVALGLMESEQLRQKQRDLEQEGLVAVRRLLTRECAPPAQELGGLFQAFVEKETQAYS", "length": 420, "header": "tr|F1N3R0-1|F1N3R0_BOVIN Isoform 1 of Secernin-2 OS=Bos taurus OX=9913 GN=SCRN2 PE=3 SV=3 CANONICAL=F1N3R0-1" }, "locus": { "chromosome": "19", "start_pos": 38626700, "end_pos": 38623604, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000002390.5", "url": "https://www.ensembl.org/id/ENSBTAT00000002390.5" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000002390.5", "url": "https://www.ensembl.org/id/ENSBTAP00000002390.5" } ] } } ], 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] } ], "function": [ { "annotation": "May be involved in transcriptional regulation.", "evidence": [ { "database": "UniProtKB", "id": "F1N3Y9", "url": "https://www.uniprot.org/uniprotkb/F1N3Y9#function" }, { "database": "UniProtKB", "id": "ARBA00003767", "url": "https://www.uniprot.org/uniprotkb/ARBA00003767#function" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Bos taurus", "taxid": 9913, "evidence": [ { "database": "UniProtKB", "id": "F1N3Y9", "url": "https://www.uniprot.org/uniprotkb/F1N3Y9" } ], "common_name": "Bovine", "glygen_name": "Bovine", "reference_species": "Bos taurus [9913]" } ], "gene": [ { "name": "ZNF771", "url": "https://www.uniprot.org/uniprotkb/F1N3Y9", "locus": { "chromosome": "25", "start_pos": 26592180, "end_pos": 26583806, "strand": "-", "evidence": [ { "database": "Ensembl Gene", "id": "ENSBTAG00000021222", "url": "https://www.ensembl.org/id/ENSBTAG00000021222" } ] } } ], "crossref": [ { "id": "F1N3Y9", "url": "https://alphafold.ebi.ac.uk/entry/F1N3Y9", "database": "AlphaFoldDB", "categories": [] }, { "id": "ENSBTAG00000021222", "url": "https://bgee.org/?page=gene&gene_id=ENSBTAG00000021222", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "100135053", "url": "https://www.ncbi.nlm.nih.gov/gene/100135053", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR013087", "url": "https://www.ebi.ac.uk/interpro/entry/IPR013087", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR036236", "url": "https://www.ebi.ac.uk/interpro/entry/IPR036236", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "RLYICEG", "url": "https://omabrowser.org/oma/group/RLYICEG/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "F1N3Y9", "url": "https://www.orthodb.org/?gene=F1N3Y9", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": 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"MPGEQQTEEEEEEEMQEEMVLLVKGEEEEGEEKYEVVKLKIPMDNKEVPSEAPAPSADPARPHACRDCGRAFARRSTLAKHVRIHTGERPFACTECGRRFSQKSALTKHSRTHTGERPYECPECDKRFSAASNLRQHRRRHTGEKPYACAQCGRRFAQSSNYAQHLRVHTGEKPYACPDCGRAFGGSSCLARHRRTHTGERPYACADCGTRFAQSSALAKHRRVHTGEKPHRCPVCGRGFGHRSNLAEHARTHTGERPYPCSECGRRFRLSSHFIRHRRAHMRRRLYICAGCGRDFKLPAGATATERCPDCEGS", "length": 314, "header": "tr|F1N3Y9-1|F1N3Y9_BOVIN Isoform 1 of Zinc finger protein 771 OS=Bos taurus OX=9913 GN=ZNF771 PE=3 SV=1 CANONICAL=F1N3Y9-1" }, "isoforms": [ { "isoform_ac": "F1N3Y9-1", "url": "https://www.uniprot.org/uniprotkb/F1N3Y9/entry", "sequence": { "sequence": "MPGEQQTEEEEEEEMQEEMVLLVKGEEEEGEEKYEVVKLKIPMDNKEVPSEAPAPSADPARPHACRDCGRAFARRSTLAKHVRIHTGERPFACTECGRRFSQKSALTKHSRTHTGERPYECPECDKRFSAASNLRQHRRRHTGEKPYACAQCGRRFAQSSNYAQHLRVHTGEKPYACPDCGRAFGGSSCLARHRRTHTGERPYACADCGTRFAQSSALAKHRRVHTGEKPHRCPVCGRGFGHRSNLAEHARTHTGERPYPCSECGRRFRLSSHFIRHRRAHMRRRLYICAGCGRDFKLPAGATATERCPDCEGS", "length": 314, "header": "tr|F1N3Y9-1|F1N3Y9_BOVIN Isoform 1 of Zinc finger protein 771 OS=Bos taurus OX=9913 GN=ZNF771 PE=3 SV=1 CANONICAL=F1N3Y9-1" }, "locus": { "chromosome": "25", "start_pos": 26591922, "end_pos": 26584547, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000002792.4", "url": "https://www.ensembl.org/id/ENSBTAT00000002792.4" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000002792.3", "url": "https://www.ensembl.org/id/ENSBTAP00000002792.3" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [], "orthologs": [ { "uniprot_canonical_ac": "A0A287B3R4-1", "protein_name": "Zinc finger protein 771", "gene_name": "ZNF771", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": 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317 }, "evidence": [ { "id": "F1N3Y9", "url": "https://omabrowser.org/oma/group/F1N3Y9/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" } ], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 3, "go_terms": [ { "name": "nucleus", "id": "GO:0005634", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005634", "evidence": [ { "database": "UniProtKB", "id": "F1N3Y9", "url": "https://www.uniprot.org/uniprotkb/F1N3Y9" } ], "pmid": "" }, { "name": "nucleoplasm", "id": "GO:0005654", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005654", "evidence": [ { "database": "UniProtKB", "id": "F1N3Y9", "url": "https://www.uniprot.org/uniprotkb/F1N3Y9" } ], "pmid": "" }, { "name": "nucleolus", "id": "GO:0005730", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005730", "evidence": [ { "database": "UniProtKB", "id": "F1N3Y9", "url": "https://www.uniprot.org/uniprotkb/F1N3Y9" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 2, "go_terms": [ { 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"categories": [ "Genome Annotation" ] }, { "id": "IPR013087", "url": "https://www.ebi.ac.uk/interpro/entry/IPR013087", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR036236", "url": "https://www.ebi.ac.uk/interpro/entry/IPR036236", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR050331", "url": "https://www.ebi.ac.uk/interpro/entry/IPR050331", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "bta:511703", "url": "https://www.genome.jp/dbget-bin/www_bget?bta:511703", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "VESCAVH", "url": "https://omabrowser.org/oma/group/VESCAVH/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "F1N440", "url": "https://www.orthodb.org/?gene=F1N440", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR16515", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR16515", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR16515:SF49", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR16515:SF49", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00096", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00096", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "NP_001180047", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001180047", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "F1N440", "url": "https://www.uniprot.org/uniprotkb/F1N440", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "F1N440-1", "url": "https://www.uniprot.org/uniprotkb/F1N440-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MSHTASSCQELAENRAVHGAGMAQEDSRRGQVPSSFYHGANQELDLSTKVYKRESGSPYSVLVDTKMSKPHLHETEEQPYFRETRAVSDVHGVKEDRENSDDTEEEEEEEEVSYKREQIIVEVNLNNQTLNVSKGEKGVSSQSKETPVLKTSSEEEEEESEEEATDDSNDYGENERQKKKEKTVEKVSVTQRRTRRAASVAAAATSPTPRATRGRRKSVEPPKRKKRATKEPKAAVQKAKCEEKETLTCEKCPRVFNTRWYLEKHMNVTHRRMQICDKCGKKFVLESELSLHQQTDCEKNIQCVSCNKSFKKLWSLHEHIKIVHGYAEKKFSCEICEKKFYTMAHVRKHMVAHTKDMPFTCETCGKSFKRSMSLKVHSLQHSGEKPFRCENCDERFQYKYQLRSHMSIHIGHKQFMCQWCGKDFNMKQYFDEHMKTHTGEKPFICEICGKSFTSRPNMKRHRRTHTGEKPYPCDVCGQRFRFSNMLKAHKEKCFRVTSPVNVPPAVQIPLTTSPATPVPSAVNTPTTPAPPVSMNPVGTLPPRPIPHPFSHLHIHAHPHHPHHLPIPPVPHLPPPPALFKSEPLNNRGQGEDTFLRHLAEKNSAAQHH", "length": 608, "header": "tr|F1N440-1|F1N440_BOVIN Isoform 1 of Zinc finger protein 652 OS=Bos taurus OX=9913 GN=ZNF652 PE=3 SV=2 CANONICAL=F1N440-1" }, "isoforms": [ { "isoform_ac": "F1N440-1", "url": "https://www.uniprot.org/uniprotkb/F1N440/entry", "sequence": { "sequence": "MSHTASSCQELAENRAVHGAGMAQEDSRRGQVPSSFYHGANQELDLSTKVYKRESGSPYSVLVDTKMSKPHLHETEEQPYFRETRAVSDVHGVKEDRENSDDTEEEEEEEEVSYKREQIIVEVNLNNQTLNVSKGEKGVSSQSKETPVLKTSSEEEEEESEEEATDDSNDYGENERQKKKEKTVEKVSVTQRRTRRAASVAAAATSPTPRATRGRRKSVEPPKRKKRATKEPKAAVQKAKCEEKETLTCEKCPRVFNTRWYLEKHMNVTHRRMQICDKCGKKFVLESELSLHQQTDCEKNIQCVSCNKSFKKLWSLHEHIKIVHGYAEKKFSCEICEKKFYTMAHVRKHMVAHTKDMPFTCETCGKSFKRSMSLKVHSLQHSGEKPFRCENCDERFQYKYQLRSHMSIHIGHKQFMCQWCGKDFNMKQYFDEHMKTHTGEKPFICEICGKSFTSRPNMKRHRRTHTGEKPYPCDVCGQRFRFSNMLKAHKEKCFRVTSPVNVPPAVQIPLTTSPATPVPSAVNTPTTPAPPVSMNPVGTLPPRPIPHPFSHLHIHAHPHHPHHLPIPPVPHLPPPPALFKSEPLNNRGQGEDTFLRHLAEKNSAAQHH", "length": 608, "header": "tr|F1N440-1|F1N440_BOVIN Isoform 1 of Zinc finger protein 652 OS=Bos taurus OX=9913 GN=ZNF652 PE=3 SV=2 CANONICAL=F1N440-1" }, "locus": { "chromosome": "19", "start_pos": 37299154, "end_pos": 37285963, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000002495.6", "url": "https://www.ensembl.org/id/ENSBTAT00000002495.6" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000002495.3", "url": "https://www.ensembl.org/id/ENSBTAP00000002495.3" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [ { "id": "bta:511703", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?bta:511703", "resource": "KEGG Pathway" } ], "orthologs": [ { "uniprot_canonical_ac": "A1L1J6-1", "protein_name": "Zinc finger protein 652", "gene_name": "Znf652", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MSYTASPCQELVEPCAVHAEGMAQEESHRSQAPPTFYHGASQELDLSTKVYKRESGSPYSVLADSKMSKPHLHETEEQPYFREPRAVSDVHTVKEDRENSDDTEEEEEVSYKREQIIVEVNLNNQTLNVSKGEKGVSSQSKETPVLKTSSEEEEEETEEDATDNSSDYGENGRQKKKEKQVEKVRVTQRRTRRAASVAAATTSPTPRTTRGRRKSAELPKRKKRAAKEPKAPVQKAKCDEKETLTCEKCPRVFNTRWYLEKHMNVTHRRMQICDKCGKKFVLESELSLHQQTDCEKNIQCVSCNKSFKKLWSLHEHIKIVHGYAEKKFACEICEKKFYTMAHVRKHMVAHTKDMPFTCETCGKSFKRSMSLKVHSLQHSGEKPFRCENCDERFQYKYQLRSHMSIHIGHKQFMCQWCGKDFNMKQYFDEHMKTHTGEKPFICEICGKSFTSRPNMKRHRRTHTGEKPYPCDVCGQRFRFSNMLKAHKEKCFRVTSPVNVPPAVQIPLASAPAAPAPAVANTPTSPAPAVSMNPVGSALPSRPVPHPFSHLHIHTHPHHSHHLPIPPVPHLPPPPALFKSEPLNHRSQSEDTFLRHLAEKNSPAQAQHH", "length": 608 }, "evidence": [ { "id": "F1N440", "url": "https://omabrowser.org/oma/group/F1N440/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "E1BQL6-1", "protein_name": "Zinc finger protein 652", "gene_name": "ZNF652", "tax_id": 9031, "organism": "Gallus gallus", "sequence": { "sequence": "MSQTANSCQQLVENCAVHVAGMAQEDSRRGQVPPTFYHGASQELDLSTKVYKRESGSPYPVLVDSKMSKPHLHEREEQPYFRENRSVGEVRAVKEDRENSDDSEEEEEEEDEVTYKREQIIVEVNLNNQTLNVSKGEKGVPSQSKETAVLKTSSEEEEGDSGEEATEDSNDYEENERQKKKEKRVEKVSVAQRRTRRAASAAAATTSPSPRTTRGRRKSVEPPKRKKKAAKEPKAPVQKSKCEEKETLTCEKCPRVFNTRWYLEKHMNVTHRRMQICDKCGKKFVLESELSLHQQTDCEKNIQCVSCNKSFKKLWSLHEHIKIVHGYAEKKFSCEICEKKFYTMAHVRKHMVAHTKDMPFTCETCGKSFKRSMSLKVHSLQHSGEKPFRCENCDERFQYKYQLRSHMSIHIGHKQFMCQWCGKDFNMKQYFDEHMKTHTGEKPFICEICGKSFTSRPNMKRHRRTHTGEKPYPCDVCGQRFRFSNMLKAHKEKCFRVTSPVNVSSAVQIPLSTTSATTVPAVVNTPTAPTPPINLNPVSTLPPRPIPHPYSHLHLHPHPHHPHHLPVPPVPHLPPPPALFKSEPLNHRGQSEDSFLRHLAEKNSSAQHH", "length": 609 }, "evidence": [ { "id": "F1N440", "url": "https://omabrowser.org/oma/group/F1N440/", "database": "OMA" } ], "glygen_name": "Chicken", "common_name": "Chicken" }, { "uniprot_canonical_ac": "F1RWF4-1", "protein_name": "Zinc finger protein 652", "gene_name": "ZNF652", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MSHTTSSCQELVENCAVHVAGMAQEESRRGQVPSTFYHGANQELDLSTKVYKRESGSPYSVLVDTKMSKPHLHETEEQPFFRETRAVSDVHAVKEDRENSDDTEEEEEEEEEEVSYKREQIIVEVNLNNQTLNVSKGEKGVSSQSKETPVLKTSSEEEEEESEEEATDDSNDYGENERQKKKEKIVEKVSVTQRRTRRAASVAAAATSPTPRATRGRRKSVEPPKRKKRAAKEPKAPVQKAKCEEKETLTCEKCPRVFNTRWYLEKHMNVTHRRMQICDKCGKKFVLESELSLHQQTDCEKNIQCVSCNKSFKKLWSLHEHIKIVHGYAEKKFSCEICEKKFYTMAHVRKHMVAHTKDMPFTCETCGKSFKRSMSLKVHSLQHSGEKPFRCENCDERFQYKYQLRSHMSIHIGHKQFMCQWCGKDFNMKQYFDEHMKTHTGEKPFICEICGKSFTSRPNMKRHRRTHTGEKPYPCDVCGQRFRFSNMLKAHKEKCFRVTSPVNVPPAVQIPLTSAPATPVPSVVNTPATPAPPITMNPVSTLPPRPIPHPFSHLHIHAHPHHPHHLPIPPVPHLPPLQLSLRASP", "length": 585 }, "evidence": [ { "id": "F1N440", "url": "https://omabrowser.org/oma/group/F1N440/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "G3HJP5-1", "protein_name": "Zinc finger protein 652", "gene_name": "Znf652", "tax_id": 10029, "organism": "Cricetulus griseus", "sequence": { "sequence": "MSYPASPCQELAENCAVHATGMAQEESRRSQAPPAFYRGASQELDLSTKVYKRESGSPYSVLVDTKMSKPHLHETEEQPYFRETRAVSDVHTVKEDRENSDDTEEEEEVSYKREQIIVEVNLNNQTLNVSKGEKGVSSQSKETPVLKTSSEEGEEESEEATDDSNDYGENERQKKKEKRAEKVRVTQRRTRRTASVAAAATSPTPRTTRGRRKSAELPKRKKRATKEPKAAVQKAKCEEKETLTCEKCPRVFNTRWYLEKHMNVTHRRMQICDKCGKKFVLESELSLHQQTDCEKNIQCVSCNKSFKKLWSLHEHIKIVHGYAEKKFACEICEKKFYTMAHVRKHMVAHTKDMPFTCETCGKSFKRSMSLKVHSLQHSGEKPFRCENCDERFQYKYQLRSHMSIHIGHKQFMCQWCGKDFNMKQYFDEHMKTHTGEKPFICEICGKSFTSRPNMKRHRRTHTGEKPYPCDVCGQRFRFSNMLKAHKEKCFRVTSPVNVPPAVQIPLASAPAAPAPAVASTPTSPAPAVSMNPVGGALPSRPVPHPFSHLHIPTHPHHAHHLPIPPVPHLPPPPALFKSEPLNHRGQSEDTFLRHLAEKNNTAQAQHH", "length": 607 }, "evidence": [ { "id": "F1N440", "url": "https://omabrowser.org/oma/group/F1N440/", "database": "OMA" } ], "glygen_name": "Hamster", "common_name": "Chinese hamster" }, { "uniprot_canonical_ac": "Q5DU09-1", "protein_name": "Zinc finger protein 652", "gene_name": "Znf652", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MSYTASPCPELVEPCAVHAEGMAQEESHRSQAPPTFYHGASQELDLSTKVYKRESGSPYSVLADTKMSKPHLHETEEQPYFREPRAVSDVHTVKEDRENSDDTEEEEEVSYKREQIIVEVNLNNQTLNVSKGEKGVSSQSKETPVLKTSSEEDEEETEEEATDNSSDYGENGRQKKKEKQVERVRVTQRRTRRAASAAAATTSPAPRTTRGRRKSAELPKRKKRATKEAKAPVQKAKCEEKETLTCEKCPRVFNTRWYLEKHMNVTHRRMQICDKCGKKFVLESELSLHQQTDCEKNIQCVSCNKSFKKLWSLHEHIKIVHGYAEKKFACEICEKKFYTMAHVRKHMVAHTKDMPFTCETCGKSFKRSMSLKVHSLQHSGEKPFRCENCDERFQYKYQLRSHMSIHIGHKQFMCQWCGKDFNMKQYFDEHMKTHTGEKPFICEICGKSFTSRPNMKRHRRTHTGEKPYPCDVCGQRFRFSNMLKAHKEKCFRVTSPVNVPPAVQIPLASAPAAPAPAVANTPTSPAPAVSMSPVGAVLPSRPVPHPFSHLHIHTHPHHAHHLPIPPVPHLPPPPALFKSEPLNHRSQSEDTFLRHLAEKNSAAPAQHH", "length": 608 }, "evidence": [ { "id": "F1N440", "url": "https://omabrowser.org/oma/group/F1N440/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q9Y2D9-1", "protein_name": "Zinc finger protein 652", "gene_name": "ZNF652", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MSHTASSCQELVENCAVHVAGMAQEDSRRGQVPSSFYHGANQELDLSTKVYKRESGSPYSVLVDTKMSKPHLHETEEQPYFRETRAVSDVHAVKEDRENSDDTEEEEEEVSYKREQIIVEVNLNNQTLNVSKGEKGVSSQSKETPVLKTSSEEEEEESEEEATDDSNDYGENEKQKKKEKIVEKVSVTQRRTRRAASVAAATTSPTPRTTRGRRKSVEPPKRKKRATKEPKAPVQKAKCEEKETLTCEKCPRVFNTRWYLEKHMNVTHRRMQICDKCGKKFVLESELSLHQQTDCEKNIQCVSCNKSFKKLWSLHEHIKIVHGYAEKKFSCEICEKKFYTMAHVRKHMVAHTKDMPFTCETCGKSFKRSMSLKVHSLQHSGEKPFRCENCDERFQYKYQLRSHMSIHIGHKQFMCQWCGKDFNMKQYFDEHMKTHTGEKPFICEICGKSFTSRPNMKRHRRTHTGEKPYPCDVCGQRFRFSNMLKAHKEKCFRVTSPVNVPPAVQIPLTTSPATPVPSVVNTATTPTPPINMNPVSTLPPRPIPHPFSHLHIHPHPHHPHHLPIPPVPHLPPPPALFKSEPLNHRGQSEDNFLRHLAEKNSSAQHH", "length": 606 }, "evidence": [ { "id": "F1N440", "url": "https://omabrowser.org/oma/group/F1N440/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" } ], "go_annotation": { "categories": [ { "name": "Molecular Function", "total": 4, "go_terms": [ { "name": "DNA-binding transcription factor activity", "id": "GO:0003700", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003700", "evidence": [ { "database": "UniProtKB", "id": "F1N440", "url": "https://www.uniprot.org/uniprotkb/F1N440" } ], "pmid": "" }, { "name": "zinc ion binding", "id": "GO:0008270", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008270", "evidence": [ { "database": "UniProtKB", "id": "F1N440", "url": "https://www.uniprot.org/uniprotkb/F1N440" } ], "pmid": "" }, { "name": "DNA-binding transcription repressor activity, RNA polymerase II-specific", "id": "GO:0001227", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0001227", "evidence": [ { "database": "UniProtKB", "id": "F1N440", "url": "https://www.uniprot.org/uniprotkb/F1N440" } ], "pmid": "" }, { "name": "RNA polymerase II cis-regulatory region sequence-specific DNA binding", "id": "GO:0000978", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000978", "evidence": [ { "database": "UniProtKB", "id": "F1N440", "url": "https://www.uniprot.org/uniprotkb/F1N440" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 1, "go_terms": [ { "name": "nucleus", "id": "GO:0005634", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005634", "evidence": [ { "database": "UniProtKB", "id": "F1N440", "url": "https://www.uniprot.org/uniprotkb/F1N440" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 2, "go_terms": [ { "name": "DNA-templated transcription", "id": "GO:0006351", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006351", "evidence": [ { "database": "UniProtKB", "id": "F1N440", "url": "https://www.uniprot.org/uniprotkb/F1N440" } ], "pmid": "" }, { "name": "regulation of transcription by RNA polymerase II", "id": "GO:0006357", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006357", "evidence": [ { "database": "UniProtKB", "id": "F1N440", "url": "https://www.uniprot.org/uniprotkb/F1N440" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 127, "end_pos": 129, "annotation": "n_glycosylation_sequon" }, { "start_pos": 131, "end_pos": 133, "annotation": "n_glycosylation_sequon" }, { "start_pos": 267, "end_pos": 269, "annotation": "n_glycosylation_sequon" }, { "start_pos": 307, "end_pos": 309, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [ { "pdb_id": "AF-F1N440-F1", "pdb_chain": "global", "start_pos": 1, "end_pos": 608, "overlap": "1.0", "method": "AlphaFold", "type": "alphafold", "resolution": -1.0, "url": "https://data.glygen.org/ln2downloads/pdb/current/AF-F1N440-F1.pdb", "url_external": "https://alphafold.ebi.ac.uk/entry/F1N440" } ], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "F1N440", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1N440" }, { "id": "PS50157", "database": "PROSITE", "url": "https://prosite.expasy.org/PS50157" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "C2H2-type", "eco_id": "ECO_0000259", "start_pos": 247, "end_pos": 275, "start_aa": "Leu", "end_aa": "Ile", "glycosite_overlap": [] } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "homologset.oma", "label": "OMA Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 127, "end_pos": 129 }, { "start_pos": 131, "end_pos": 133 }, { "start_pos": 267, "end_pos": 269 }, { "start_pos": 307, "end_pos": 309 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, 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"UniProtKB", "categories": [ "Protein" ] }, { "id": "F1N461-1", "url": "https://www.uniprot.org/uniprotkb/F1N461-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MGCLGNSKTSEDQGVDEKERREANKKIEKQLQKERLAYKATHRLLLLGAGESGKSTIVKQMRILHVNGFNPEEKKQKILDIRKNVKDAIVTIVSAMSTIIPPVPLANPENQFRSDYIKSIAPITDFEYSQEFFDHVKKLWDDEGVKACFERSNEYQLIDCAQYFLERIDSVSLVDYTPTDQDLLRCRVLTSGIFETRFQVDKVNFHMFDVGGQRDERRKWIQCFNDVTAIIYVAACSSYNMVIREDNNTNRLRESLDLFESIWNNRWLRTISIILFLNKQDMLAEKVLAGKSKIEDYFPEYANYTVPEDATPDAGEDPKVTRAKFFIRDLFLRISTATGDGKHYCYPHFTCAVDTENIRRVFNDCRDIIQRMHLKQYELL", "length": 380, "header": "tr|F1N461-1|F1N461_BOVIN Isoform 1 of G protein subunit alpha L OS=Bos taurus OX=9913 GN=GNAL PE=3 SV=2 CANONICAL=F1N461-1" }, "isoforms": [ { "isoform_ac": "A0A3Q1M3D6-1", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1M3D6/entry", "sequence": { "sequence": 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"https://www.uniprot.org/uniprotkb/F1N461/entry", "sequence": { "sequence": "MGCLGNSKTSEDQGVDEKERREANKKIEKQLQKERLAYKATHRLLLLGAGESGKSTIVKQMRILHVNGFNPEEKKQKILDIRKNVKDAIVTIVSAMSTIIPPVPLANPENQFRSDYIKSIAPITDFEYSQEFFDHVKKLWDDEGVKACFERSNEYQLIDCAQYFLERIDSVSLVDYTPTDQDLLRCRVLTSGIFETRFQVDKVNFHMFDVGGQRDERRKWIQCFNDVTAIIYVAACSSYNMVIREDNNTNRLRESLDLFESIWNNRWLRTISIILFLNKQDMLAEKVLAGKSKIEDYFPEYANYTVPEDATPDAGEDPKVTRAKFFIRDLFLRISTATGDGKHYCYPHFTCAVDTENIRRVFNDCRDIIQRMHLKQYELL", "length": 380, "header": "tr|F1N461-1|F1N461_BOVIN Isoform 1 of G protein subunit alpha L OS=Bos taurus OX=9913 GN=GNAL PE=3 SV=2 CANONICAL=F1N461-1" }, "locus": { "chromosome": "24", "start_pos": 42721733, "end_pos": 42672227, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000002747.8", "url": "https://www.ensembl.org/id/ENSBTAT00000002747.8" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000002747.5", "url": "https://www.ensembl.org/id/ENSBTAP00000002747.5" } ] } } ], "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "other", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 311, "start_aa": "Thr", "end_pos": 311, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr311", "evidence": [ { "id": "", "database": "GlyGen", "url": "https://data.glygen.org/" } ], "filter_code": "000000000000000010000.00000000001000.0.01000" } ], "phosphorylation": [], "glycation": [], "keywords": [ "glycoprotein", "glycoprotein_predicted" ], "publication": [], "pathway": [ { "id": "R-BTA-170660", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-BTA-170660", "resource": "Reactome", "description": "Adenylate cyclase activating pathway" }, { "id": "R-BTA-170670", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-BTA-170670", "resource": 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"uniprot_canonical_ac": "E1BS74-1", "protein_name": "G protein subunit alpha L", "gene_name": "GNAL", "tax_id": 9031, "organism": "Gallus gallus", "sequence": { "sequence": "MGCLGNSKTEDQRIDEKAQREANKKIEKQLQKERLAYKATHRLLLLGAGESGKSTIVKQMRILHVNGFNSEEKKQKILDIRKNVKDAIVTIVSAMSTLIPPVPLANPENQFRMDYIKSIAPLSDFDYTQEFFEHAKKLWDDEGVKACFERSNEYQLIDCAQYFLERIDSVSMDDYTPTDQDLLRCRVLTSGIFETRFQVDKVNFHMFDVGGQRDERRKWIQCFNDVTAIIFVVACSSYNMVIREDNNTNRLRESLDLFKSIWNNRWLRTISIILFLNKQDMLAEKVLAGKSKIEDYFPEYAHYTVPEDATPDAGEDPKVTRAKFFIRDEFLRISTASGDGRHYCYPHFTCAVDTENIRRVFNDCRDIIQRMHLRQYELL", "length": 379 }, "evidence": [ { "id": "F1N461", "url": "https://omabrowser.org/oma/group/F1N461/", "database": "OMA" } ], "glygen_name": "Chicken", "common_name": "Chicken" }, { "uniprot_canonical_ac": "P38405-1", "protein_name": "Guanine nucleotide-binding protein G(olf) subunit alpha", "gene_name": "GNAL", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MGCLGGNSKTTEDQGVDEKERREANKKIEKQLQKERLAYKATHRLLLLGAGESGKSTIVKQMRILHVNGFNPEEKKQKILDIRKNVKDAIVTIVSAMSTIIPPVPLANPENQFRSDYIKSIAPITDFEYSQEFFDHVKKLWDDEGVKACFERSNEYQLIDCAQYFLERIDSVSLVDYTPTDQDLLRCRVLTSGIFETRFQVDKVNFHMFDVGGQRDERRKWIQCFNDVTAIIYVAACSSYNMVIREDNNTNRLRESLDLFESIWNNRWLRTISIILFLNKQDMLAEKVLAGKSKIEDYFPEYANYTVPEDATPDAGEDPKVTRAKFFIRDLFLRISTATGDGKHYCYPHFTCAVDTENIRRVFNDCRDIIQRMHLKQYELL", "length": 381 }, "evidence": [ { "id": "F1N461", "url": "https://omabrowser.org/oma/group/F1N461/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "P38406-1", "protein_name": "Guanine nucleotide-binding protein G(olf) subunit alpha", "gene_name": "Gnal", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": 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"MAALTTVVVAAAATAVAGAVAGAGAAPGTGVGAAVPQQSDGCLGTSGGIRPFHLQNWKQKVSRTKKAEFIRTAEKYKNQVINLEKDKHSHFYNQKSDFRIEHSMLEELENKLINSRKTERAKIQQQLAKIYNNVKKLQHQLKDAKPTPDFVEKLREMMEEIENAINTFKEEQRLIYEELIKEEKTTNNELNAISRKIDTWALGNSETEKAFRAALSKVPVDKVTPSALPEEVVEFETFLQQTGGRQGGWDDYDHQNFVKMRSKHKGKPVFMGEVLEHLPGRTQDEVQQHEKWYQKFLALEERKKESIQHWKTKKQQKKEEIFKLKEKDSIQVLSHSKQEDNQKQKEEQRKKQKLAIEAWKKQRSIEMSMKNASQLKEEEEKEKKQQRERQRQCKLKLLLETYTQQKKEQEEFLRLEKEIREKTEKAEKRKTAADEISRFQERDLHKLELKILNRQLKEDEKAEKQRKLAKLKEKVENNVSRDPSRLYKPTKGWEERTKKIGPAGSGPLLHIPHRAIPTWRQGV", "length": 523, "header": "tr|F1N4A5-1|F1N4A5_BOVIN Isoform 1 of Coiled-coil domain containing 112 OS=Bos taurus OX=9913 GN=CCDC112 PE=4 SV=3 CANONICAL=F1N4A5-1" }, "isoforms": [ { "isoform_ac": "F1N4A5-1", "url": "https://www.uniprot.org/uniprotkb/F1N4A5/entry", "sequence": { "sequence": "MAALTTVVVAAAATAVAGAVAGAGAAPGTGVGAAVPQQSDGCLGTSGGIRPFHLQNWKQKVSRTKKAEFIRTAEKYKNQVINLEKDKHSHFYNQKSDFRIEHSMLEELENKLINSRKTERAKIQQQLAKIYNNVKKLQHQLKDAKPTPDFVEKLREMMEEIENAINTFKEEQRLIYEELIKEEKTTNNELNAISRKIDTWALGNSETEKAFRAALSKVPVDKVTPSALPEEVVEFETFLQQTGGRQGGWDDYDHQNFVKMRSKHKGKPVFMGEVLEHLPGRTQDEVQQHEKWYQKFLALEERKKESIQHWKTKKQQKKEEIFKLKEKDSIQVLSHSKQEDNQKQKEEQRKKQKLAIEAWKKQRSIEMSMKNASQLKEEEEKEKKQQRERQRQCKLKLLLETYTQQKKEQEEFLRLEKEIREKTEKAEKRKTAADEISRFQERDLHKLELKILNRQLKEDEKAEKQRKLAKLKEKVENNVSRDPSRLYKPTKGWEERTKKIGPAGSGPLLHIPHRAIPTWRQGV", "length": 523, "header": "tr|F1N4A5-1|F1N4A5_BOVIN Isoform 1 of Coiled-coil domain containing 112 OS=Bos taurus OX=9913 GN=CCDC112 PE=4 SV=3 CANONICAL=F1N4A5-1" }, "locus": { "chromosome": "10", "start_pos": 4139082, "end_pos": 4109543, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000002468.6", "url": "https://www.ensembl.org/id/ENSBTAT00000002468.6" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000002468.6", "url": "https://www.ensembl.org/id/ENSBTAP00000002468.6" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [ { "id": "bta:509840", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?bta:509840", "resource": "KEGG Pathway" } ], "orthologs": [ { "uniprot_canonical_ac": "A0A8V0X6W8-1", "protein_name": "Coiled-coil domain containing 112", "gene_name": "CCDC112", "tax_id": 9031, "organism": "Gallus gallus", "sequence": { "sequence": "MAALAAVCAAAAGQQQNDSFFSAAGAARPIQNCKMKAEQAKKTEFVRIAGKLRTQLANTQKDKNGCLYNRKSDSRAEYSILEELEHQMSVHRKTEKTKILQQLTKIRNNVKRLQRQLDDVKPTSEFVDKLKEMLEEIEHAINTYKDEQRQIYEQLLKDEKTAVNELSIFEKKVELWATGSSTTEKVLKLPSARISVNKTLESHLPEEVVEFERFLQQTGGRQGGWDDCDHQNFLKVWTKHRGKLSYVDEALEYLCGRTKEDVEQHGIWYQEFLILQDRKKESIKKWKEKLQREKEERLKKKEKSEKIVERLQYEEDQMQKAEERRRQQAAISAWKKQKAENLQWSKFHN", "length": 349 }, "evidence": [ { "id": "F1N4A5", "url": "https://omabrowser.org/oma/group/F1N4A5/", "database": "OMA" } ], "glygen_name": "Chicken", "common_name": "Chicken" }, { "uniprot_canonical_ac": "A0AUP1-1", "protein_name": "Coiled-coil domain-containing protein 112", "gene_name": "Ccdc112", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MEKDKHSHFYNQRGDFRTEYNMLEELENKLINSRKTERAKIQQQLAKIHNNVKKLQNQLKDVKPTPDVVEKLREMMEEIENAINTFKEEQRLIYEELIQEEKTTNNELSAVSRRIESWALGNSETEKAFRAISSKVPVDRVTQRTLPEQVVEFEKFLQQTGGRQGGWDALDHQNFVKVRNKHKGKPTFMKEVVEHLPGRTLDEVQQHEKWYQKFLTLEEKKKESIQNWKTKKQQKKEEILKLKEKVDTVPLPSQSKAEDSPKQREEQRKKQKLAVEAWKKRKSLEMSAKLASQLREEEEKERKQQRERQRQSKLKLLLESYTQQRREQEEFLRLEQEIKEKAEKAEKRKTAADELARFQERDLHKLELKILDRQAKEEEKAEKQRRLTKLKEKVENNVSRDPSRLYKPTKGWEERTKKIGPSGSGPLLHIPHRAIPTWRQGI", "length": 442 }, "evidence": [ { "id": "F1N4A5", "url": "https://omabrowser.org/oma/group/F1N4A5/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "D4A095-1", "protein_name": "Coiled-coil domain containing 112", "gene_name": "Ccdc112", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MAALTTVVVAAAATAVAGAVAGAGAAAGTGVGAAPTPQQSNVGFSASGGIRPFQLQNWKQKVSWTKKAEFIRTAEKLKNQVIVIEKDKHSHFYNQRGHFRTEYSLLEELENKLINSRKMERAKIQQQLAKIHNNVKKLQNQLKSVKPTPDFVEKLREMMEEIENAINTFKEEQRLIYEELIQEEKTTNNELSAISRRIESWALGNSETERAFRAISSKLPVDRVTPSTLPEEVIEFEKFLQQTGGRQGGWDDLDHQNFVKVRNKHKGKLTFMKEVIEHLPGRTLDEIQQHEKWYQKFLALEEKKKESIQNWKIKKQQKKEEILKLKEKADTTPPPSQSKPEDNLKQKEEQRKKQKLAVEAWKKQKSIEMSVKQASQLREEEEKERKQQRERQRQSKLKLLLESYTQQKREQEEFLRLEKEIKEKTEKAEKRKTAADEISRFQERDLHKLELKILDRQAKEEEKAEKQRRLTKLKEKVESNVGRDPSRLYKPTRGWEQRTKKIGPLDSGPLLHIPHRAIPTWRQGI", "length": 525 }, "evidence": [ { "id": "F1N4A5", "url": "https://omabrowser.org/oma/group/F1N4A5/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "Q8NEF3-1", "protein_name": "Coiled-coil domain-containing protein 112", "gene_name": "CCDC112", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MEKDKHSHFYNQKSDFRIEHSMLEELENKLIHSRKTERAKIQQQLAKIHNNVKKLQHQLKDVKPTPDFVEKLREMMEEIENAINTFKEEQRLIYEELIKEEKTTNNELSAISRKIDTWALGNSETEKAFRAISSKVPVDKVTPSTLPEEVLDFEKFLQQTGGRQGAWDDYDHQNFVKVRNKHKGKPTFMEEVLEHLPGKTQDEVQQHEKWYQKFLALEERKKESIQIWKTKKQQKREEIFKLKEKADNTPVLFHNKQEDNQKQKEEQRKKQKLAVEAWKKQKSIEMSMKCASQLKEEEEKEKKHQKERQRQFKLKLLLESYTQQKKEQEEFLRLEKEIREKAEKAEKRKNAADEISRFQERDLHKLELKILDRQAKEDEKSQKQRRLAKLKEKVENNVSRDPSRLYKPTKGWEERTKKIGPTGSGPLLHIPHRAIPTWRQGIQRRV", "length": 446 }, "evidence": [ { "id": "F1N4A5", "url": "https://omabrowser.org/oma/group/F1N4A5/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" } ], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 1, "go_terms": [ { "name": "centriolar satellite", "id": "GO:0034451", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0034451", "evidence": [ { "database": "UniProtKB", "id": "F1N4A5", "url": "https://www.uniprot.org/uniprotkb/F1N4A5" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 371, "end_pos": 373, "annotation": "n_glycosylation_sequon" }, { "start_pos": 478, "end_pos": 480, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [ { "pdb_id": "AF-F1N4A5-F1", "pdb_chain": "global", "start_pos": 1, "end_pos": 523, "overlap": "1.0", "method": "AlphaFold", "type": "alphafold", "resolution": -1.0, "url": "https://data.glygen.org/ln2downloads/pdb/current/AF-F1N4A5-F1.pdb", "url_external": "https://alphafold.ebi.ac.uk/entry/F1N4A5" } ], "lectin_list": [], "domain_list": [], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "homologset.oma", "label": "OMA Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 371, "end_pos": 373 }, { "start_pos": 478, "end_pos": 480 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ], "tool_support": { "graph_view": "yes" } }, { "uniprot_canonical_ac": "F1N4C3-1", "uniprot_ac": "F1N4C3", "uniprot_id": "F1N4C3_BOVIN", "mass": { "chemical_mass": 26527.0, "monoisotopic_mass": 26527.0 }, "refseq": { "ac": "XP_010809671", "name": "short palate, lung and nasal epithelium carcinoma-associated protein 2B isoform X1", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_010809671" }, "gene_names": [ { "name": "BPIFA2B", "type": "recommended", "evidence": [ { "id": "F1N4C3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1N4C3" } ] }, { "name": "BPIFA2B", "type": "synonym", "evidence": [ { "id": "XP_010809671", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_010809671" } ] }, { "name": "BSP30B", "type": "synonym", "evidence": [ { "id": "XP_010809671", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_010809671" } ] }, { "name": "SPLUNC2B", "type": "synonym", "evidence": [ { "id": "XP_010809671", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_010809671" } ] } ], "protein_names": [ { "name": "BPI fold containing family A, member 2B", "type": "synonym", "evidence": [ { "id": "F1N4C3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1N4C3/entry#names_and_taxonomy" } ] }, { "name": "short palate, lung and nasal epithelium carcinoma-associated protein 2B isoform X1", "type": "synonym", "evidence": [ { "id": "XP_010809671", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_010809671" } ] } ], "function": [], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Bos taurus", "taxid": 9913, "evidence": [ { "database": "UniProtKB", "id": "F1N4C3", "url": "https://www.uniprot.org/uniprotkb/F1N4C3" } ], "common_name": "Bovine", "glygen_name": "Bovine", "reference_species": "Bos taurus [9913]" } ], "gene": [ { "name": "BPIFA2B", "url": "https://www.uniprot.org/uniprotkb/F1N4C3", "locus": { "chromosome": "13", "start_pos": 62655447, "end_pos": 62645078, "strand": "-", "evidence": [ { "database": "Ensembl Gene", "id": "ENSBTAG00000019752", "url": "https://www.ensembl.org/id/ENSBTAG00000019752" } ] } } ], "crossref": [ { "id": "F1N4C3", "url": "https://alphafold.ebi.ac.uk/entry/F1N4C3", "database": "AlphaFoldDB", "categories": [] }, { "id": "ENSBTAG00000019752", "url": "https://bgee.org/?page=gene&gene_id=ENSBTAG00000019752", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "286881", "url": "https://www.ncbi.nlm.nih.gov/gene/286881", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR017942", "url": "https://www.ebi.ac.uk/interpro/entry/IPR017942", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR017943", "url": "https://www.ebi.ac.uk/interpro/entry/IPR017943", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR052507", "url": "https://www.ebi.ac.uk/interpro/entry/IPR052507", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "HEGWYAT", "url": "https://omabrowser.org/oma/group/HEGWYAT/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "F1N4C3", "url": "https://www.orthodb.org/?gene=F1N4C3", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR47145", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR47145", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR47145:SF1", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR47145:SF1", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF01273", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF01273", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "XP_010809671", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_010809671", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "F1N4C3", "url": "https://www.uniprot.org/uniprotkb/F1N4C3", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "F1N4C3-1", "url": "https://www.uniprot.org/uniprotkb/F1N4C3-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MVQLWKLVLLCGLLAGTSASLPDIRGNDVLRKLKSGLERGLDTFDSTIEIIFQNLKTELESRCSDEVVEQQETENFLEQLISRIFQVVSRLTGVRIRNVQVPDITFEATSENSANVLIPITADVTVSLPFLGEIVDLDLNVDLQTTVSIETDTEDPQVVVGECTNNPESISLTVLHSRFGLLNDVVDIGVNLARRVVSSVVEGELCPRFRELLESLDAECVEKLIGESQDTTQQEPEGSR", "length": 240, "header": "tr|F1N4C3-1|F1N4C3_BOVIN Isoform 1 of BPI fold containing family A, member 2B OS=Bos taurus OX=9913 GN=BPIFA2B PE=3 SV=1 CANONICAL=F1N4C3-1" }, "isoforms": [ { "isoform_ac": "F1N4C3-1", "url": "https://www.uniprot.org/uniprotkb/F1N4C3/entry", "sequence": { "sequence": "MVQLWKLVLLCGLLAGTSASLPDIRGNDVLRKLKSGLERGLDTFDSTIEIIFQNLKTELESRCSDEVVEQQETENFLEQLISRIFQVVSRLTGVRIRNVQVPDITFEATSENSANVLIPITADVTVSLPFLGEIVDLDLNVDLQTTVSIETDTEDPQVVVGECTNNPESISLTVLHSRFGLLNDVVDIGVNLARRVVSSVVEGELCPRFRELLESLDAECVEKLIGESQDTTQQEPEGSR", "length": 240, "header": "tr|F1N4C3-1|F1N4C3_BOVIN Isoform 1 of BPI fold containing family A, member 2B OS=Bos taurus OX=9913 GN=BPIFA2B PE=3 SV=1 CANONICAL=F1N4C3-1" }, "locus": { "chromosome": "13", "start_pos": 62654667, "end_pos": 62645907, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000026321.3", "url": "https://www.ensembl.org/id/ENSBTAT00000026321.3" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000026321.2", "url": "https://www.ensembl.org/id/ENSBTAP00000026321.2" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [], "orthologs": [], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 2, "go_terms": [ { "name": "extracellular region", "id": "GO:0005576", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005576", "evidence": [ { "database": "UniProtKB", "id": "F1N4C3", "url": "https://www.uniprot.org/uniprotkb/F1N4C3" } ], "pmid": "" }, { "name": "secretory granule", "id": "GO:0030141", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030141", "evidence": [ { "database": "UniProtKB", "id": "F1N4C3", "url": "https://www.uniprot.org/uniprotkb/F1N4C3" } ], "pmid": "" } ] }, { "name": "Molecular Function", "total": 1, "go_terms": [ { "name": "lipopolysaccharide binding", "id": "GO:0001530", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0001530", "evidence": [ { "database": "UniProtKB", "id": "F1N4C3", "url": "https://www.uniprot.org/uniprotkb/F1N4C3" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [ { "pdb_id": "AF-F1N4C3-F1", "pdb_chain": "global", "start_pos": 1, "end_pos": 240, "overlap": "1.0", "method": "AlphaFold", "type": "alphafold", "resolution": -1.0, "url": "https://data.glygen.org/ln2downloads/pdb/current/AF-F1N4C3-F1.pdb", "url_external": "https://alphafold.ebi.ac.uk/entry/F1N4C3" } ], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "F1N4C3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1N4C3" }, { "id": "PF01273", "database": "Pfam", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF01273" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "Lipid-binding serum glycoprotein N-terminal", "eco_id": "ECO_0000259", "start_pos": 44, "end_pos": 216, "start_aa": "Phe", "end_aa": "Leu", "glycosite_overlap": [] } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ], "tool_support": { "graph_view": "yes" } }, { "uniprot_canonical_ac": "F1N4G3-1", "uniprot_ac": "F1N4G3", "uniprot_id": "F1N4G3_BOVIN", "mass": { "chemical_mass": 82157.0, "monoisotopic_mass": 82157.0 }, "refseq": {}, "gene_names": [ { "name": "TXLNB", "type": "recommended", "evidence": [ { "id": "F1N4G3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1N4G3" } ] } ], "protein_names": [ { "name": "Taxilin beta", "type": "synonym", "evidence": [ { "id": "F1N4G3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1N4G3/entry#names_and_taxonomy" } ] } ], "function": [], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Bos taurus", "taxid": 9913, "evidence": [ { "database": "UniProtKB", "id": "F1N4G3", "url": "https://www.uniprot.org/uniprotkb/F1N4G3" } ], "common_name": "Bovine", "glygen_name": "Bovine", "reference_species": "Bos taurus [9913]" } ], "gene": [ { "name": "TXLNB", "url": "https://www.uniprot.org/uniprotkb/F1N4G3", "locus": { "chromosome": "9", "start_pos": 76913802, "end_pos": 76973384, "strand": "+", "evidence": [ { "database": "Ensembl Gene", "id": "ENSBTAG00000002964", "url": "https://www.ensembl.org/id/ENSBTAG00000002964" } ] } } ], "crossref": [ { "id": "F1N4G3", "url": "https://alphafold.ebi.ac.uk/entry/F1N4G3", "database": "AlphaFoldDB", "categories": [] }, { "id": "ENSBTAG00000002964", "url": "https://bgee.org/?page=gene&gene_id=ENSBTAG00000002964", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "IPR026183", "url": "https://www.ebi.ac.uk/interpro/entry/IPR026183", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "SPKMEAN", "url": "https://omabrowser.org/oma/group/SPKMEAN/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "F1N4G3", "url": "https://www.orthodb.org/?gene=F1N4G3", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR16127", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR16127", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR16127:SF10", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR16127:SF10", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF09728", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF09728", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "F1N4G3", "url": "https://www.uniprot.org/uniprotkb/F1N4G3", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "F1N4G3-1", "url": "https://www.uniprot.org/uniprotkb/F1N4G3-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MESNQPGQLSGEPPSTPVRDSSALSSQNGLEKQNDLDRSTPLPAPEQAAGIQLERGPHDISEELNRQLEDIINTYGSTAGAAGKEGTTMVKEQPENTDPPDNEDGDCEEAPEEVEREPAATGEPSTAKEPASNKEQKLEKKILKGLGKEANLLMQNLNKLQTPEEKFDFLFKKYAELLDEHRTEQRKLKLLQKKQAQIQKEKDQLQGEHSRAILARSKLESLCRELQRHNKTLKEETLQRAREEEEKRKEITSHFQNTLTDIQAQIEQQSERNMKLCQENTELAEKLKSIIDQYELREEHLDKIFKHRELQQKLVDAKLEQAQEMMKEAEERHKREKEYLLNQAAEWKLQAKVLKEQETVLQAQLTLYSGRFEEFQSTLTKSNEVFATFKQEMDKTTKKMKKLEKDTATWKARFENCNKALLDMIEEKALRAKEYECFVMKIGRLENLCRALQEERNELYKKIREAKMPKKDDQGQHTSDDEPNTSVNEEADAEEANNVHKAVQNLAAAFMIMHCPESTLDVSKEIHPEVDSPPGDCDTALRGLEQAPLSPACHSEIPLPPPNPQAEGKRVSETEPTLRAETGAEAQDDGLPGAAPADQQNRKPEAAASSQAPKAPAKPSLPVVKANEQPWKPEAASGQAQEPTAEASLPVMEVNGQSRKPEAATSGQALEPPAETFLCVMEAKCSAPPPAVGAHLPARESGCEPMTQPPPTAEGLPGGASGGPPLPKVADTNLEGVD", "length": 738, "header": "tr|F1N4G3-1|F1N4G3_BOVIN Isoform 1 of Taxilin beta OS=Bos taurus OX=9913 GN=TXLNB PE=3 SV=1 CANONICAL=F1N4G3-1" }, "isoforms": [ { "isoform_ac": "F1N4G3-1", "url": "https://www.uniprot.org/uniprotkb/F1N4G3/entry", "sequence": { "sequence": "MESNQPGQLSGEPPSTPVRDSSALSSQNGLEKQNDLDRSTPLPAPEQAAGIQLERGPHDISEELNRQLEDIINTYGSTAGAAGKEGTTMVKEQPENTDPPDNEDGDCEEAPEEVEREPAATGEPSTAKEPASNKEQKLEKKILKGLGKEANLLMQNLNKLQTPEEKFDFLFKKYAELLDEHRTEQRKLKLLQKKQAQIQKEKDQLQGEHSRAILARSKLESLCRELQRHNKTLKEETLQRAREEEEKRKEITSHFQNTLTDIQAQIEQQSERNMKLCQENTELAEKLKSIIDQYELREEHLDKIFKHRELQQKLVDAKLEQAQEMMKEAEERHKREKEYLLNQAAEWKLQAKVLKEQETVLQAQLTLYSGRFEEFQSTLTKSNEVFATFKQEMDKTTKKMKKLEKDTATWKARFENCNKALLDMIEEKALRAKEYECFVMKIGRLENLCRALQEERNELYKKIREAKMPKKDDQGQHTSDDEPNTSVNEEADAEEANNVHKAVQNLAAAFMIMHCPESTLDVSKEIHPEVDSPPGDCDTALRGLEQAPLSPACHSEIPLPPPNPQAEGKRVSETEPTLRAETGAEAQDDGLPGAAPADQQNRKPEAAASSQAPKAPAKPSLPVVKANEQPWKPEAASGQAQEPTAEASLPVMEVNGQSRKPEAATSGQALEPPAETFLCVMEAKCSAPPPAVGAHLPARESGCEPMTQPPPTAEGLPGGASGGPPLPKVADTNLEGVD", "length": 738, "header": "tr|F1N4G3-1|F1N4G3_BOVIN Isoform 1 of Taxilin beta OS=Bos taurus OX=9913 GN=TXLNB PE=3 SV=1 CANONICAL=F1N4G3-1" }, "locus": { "chromosome": "9", "start_pos": 76970603, "end_pos": 76913945, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000056227.3", "url": "https://www.ensembl.org/id/ENSBTAT00000056227.3" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000052854.1", "url": "https://www.ensembl.org/id/ENSBTAP00000052854.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [], "orthologs": [ { "uniprot_canonical_ac": "A0A0G2K2T1-1", "protein_name": "Taxilin beta", "gene_name": "Txlnb", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "METNHPDQLSVEQPNPPGDSSPLNQNVPGKQDVQQSSTSGQAAEQEASPHPEKGDHDISEELSRQLEDIINMYGSAASPTGKEGTSETKEQPQNTEAPDNEDGDYEETTEETDREPTAPEEPATVKGPVSNKEQKLEKKILKGLGKEANLLMQNLNKLQAPEEKLDFLFKKYAELLDEHRTEQKKLKLLLKQQAQTQREKDQLQSEHNRAILARSKLESLCRELQRHNKTLKEETLQRAREEEEKRKEITSHFQSTLTDIQTQIEQQSERNMKLCQENTELAEKLKSIIDQYELREEHLDKIFKHRELQQKLVDAKLEEAQELMQEAEERHRREKEYVFILLLLNQAAEWKLQAKVLKEQETVLQAQLTLYSGRFEEFQSTLTKSNEVFATFKQEMDNTTKKMKKLEKDTATWKARFENCNKALLDMIEEKALRAKEYECFVMKIQRLENLCRALQEERKELYKKIRDAKMSEKEDQVQHTSDEEPESKVSEDKQMDVEAANGVQNAVKNLATAFAILHHPEFTPDQSRERQPAVNGPPGGSDLTHQHTEPAHLNHPNPSSVSGSPQPPVGSQAGSEGGCEAAPAPTACCTPAEAELQSQGLSAGNPPDPKPQKPEAKASGQVPLSPAQGSLAVVEAKCDISPSPESERDPAVVPGCESKEHPPPEVPDIPLGPNTGLPREPDACLNGVE", "length": 690 }, "evidence": [ { "id": "F1N4G3", "url": "https://omabrowser.org/oma/group/F1N4G3/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "A0A287A996-1", "protein_name": "Taxilin beta", "gene_name": "TXLNB", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "METSQSAQLSGDPESTPPGNTSALTSQNGLEKQGDQDSSTPLPPPEEKAGVQAEQGAHDISEELNRQLEDIISMYGSAAGTAGKEGATTATEQPENTEPPDNEDRDYEEATDEMEREPVASGEPLTAKEPVSNKEQKLEKKILKGLGKEANLLMQNLNKLPTSEEKLDFLFKKYAELLDEHRTEQKKLKLLQKKQVQIQKEKDQLQSEHSRAILARSKLESLCRELQRHNKTLKEETLQRAREEEEKRKEITSHFQSTLTDIQAQIEQQSERNMKLCQENTELAEKLKSIIDQYELREEHLDKIFKHRELQQKLVDAKLEQAQEMMKEAEERHKREKEYLLNQAAEWKLQAKVLKEQETVLQAQLTLYSGRFEEFQSTLTKSNEVFATFKQEMDKTTKKMKKLEKETATWKARFENCNKALLDMIEEKTLRAKEYECFVMKIGRLENLCRALQEERNELYKKIREAKMPEKDDQSQHTSDEELESNTFVSEEVDAAAEEANRVHNAVQNLAAAFMVIHRPESTVDGSKEIPAEVGGPPEGGSTTLKEPEQAPLSPRGLSESPLPPPRPQAETAGGHEAEPPLRARSPPAESGAEAQSFRLPTEAQVDLQPRKPQAAASGQALEPLAEASLQVMEADHPAPPPAAGEHVPTAEGLPGGDTALPQGPEVADTNLEGVD", "length": 676 }, "evidence": [ { "id": "F1N4G3", "url": "https://omabrowser.org/oma/group/F1N4G3/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "A0A8M2B5F5-1", "protein_name": "Taxilin beta b isoform 1", "gene_name": "txlnbb", "tax_id": 7955, "organism": "Danio rerio", "sequence": { "sequence": "MEMETCAQSANGEMTEDLSQQLQEIINTYQLNEQKHETEEDEMEEEEEEPKSREQKMEKKMLKGLGKEAMLLMQSLNKLGTPEKKLDTLIKKHAELLEEHRSDQKQLKMLQKKFLQVLKEKDQLQGEHSRAVLARSKLESLCRELQRHNKTLKEETLQRCREDDLKRKEITTHFQSTLSDIQSQIEEHSSRNNKLCQENSELAEKLKDLISKYDQREANLEKVFKHRDLQQKLLETKLAQVNMILKESEEKHKLEKEHLLKQAAEAKLHVKLLKEQEVDMKAQLAVYSEKFDELQGSVSKSNGVYASFKQDMDKMGKKMKKLEKEASAWKSRFDGCNKALVDMVADKTLKEKEFELFTLKTQKLENLCRALQDERKTLIQKLQQPDTENTASPPSINTEKPTEKAAETKEEAAETKDQAASITEAVSKEANPSSEQVSDPPSETTLLNKELKSLKDEKARLLELAEVFSIRRHLPPQAYEDPSSCLEEEKQVDMEETGSLTDTLSEEHQELRDKDMLSVD", "length": 520 }, "evidence": [ { "id": "F1N4G3", "url": "https://omabrowser.org/oma/group/F1N4G3/", "database": "OMA" } ], "glygen_name": "Zebrafish", "common_name": "Zebrafish" }, { "uniprot_canonical_ac": "Q8N3L3-1", "protein_name": "Beta-taxilin", "gene_name": "TXLNB", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MEANHSEQLSAERQSTPPGDSSSLPSHNGLEKEDGQDSPTPVQPPEKEASVHPDISEELNRQLEDIINTYGSAASTAGKEGSARASEQPENAESPDNEDGDCEETTEEAGREPVASGEPPTVKEPVSNKEQKLEKKILKGLGKEANLLMQNLNKLQTPEEKFDFLFKKYAELLDEHRTEQKKLKLLQKKQVQIQKEKDQLQGEHSRAILARSKLESLCRELQRHNKTLKEEALQRAREEEEKRKEITSHFQSTLTDIQGQIEQQSERNMKLCQENTELAEKLKSIIDQYELREEHLDKIFKHRELQQKLVDAKLEQAQEMMKEAEERHKREKEYLLNQAAEWKLQAKVLKEQETVLQAQLTLYSGRFEEFQSTLTKSNEVFATFKQEMDKTTKKMKKLEKDTATWKARFENCNKALLDMIEEKALRAKEYECFVMKIGRLENLCRALQEERNELHKKIRDAEISEKDDQSQHNSDEEPESNVSVDQEIDAEEVNSVQTAVKNLATAFMIIHHPESTPHQSKETQPEIGSSQESADAALKEPEQPPLIPSRDSESPLPPLTPQAEAEGGSDAEPPSKASNSPAGLGAETQCEGLPVGAQADQASWKPEAEASGQAPQAPTEASLQKMEADVPAPACAAEEHVAAMVPACEPSRQPPRAAAEELPVGASAGPQPRNVADTNLEGVD", "length": 684 }, "evidence": [ { "id": "F1N4G3", "url": "https://omabrowser.org/oma/group/F1N4G3/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "Q8VBT1-1", "protein_name": "Beta-taxilin", "gene_name": "Txlnb", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MEINHPDQLSVEHPTPPGDSSSLNQNGPGKQDGERCSTSGQAPEQEGSLHPEKGAHDVAEELSRQLEDIISTYGSAASPRGKESTSETKEQPPNTEAPDNEDVDYEETTEEIDREPTAPEEPAAAKEPVSNKEQKLEKKILKGLGKEANLLMQNLNKLQAPEEKLDFLFKKYTELLDEHRTEQKKLKLLLKQQAQTQREKDQLQSEHNRAVLARSKLESLCRELQRHNKTLKEETLQRAREEEEKRKEITSHFQTTLTDIQTQIEQQSERNMKLCQENTELAEKLKSIIDQYELREEHLDKIFKHRELQQKLVDAKLEEAQELMQEAEERHRREKEYLLNQAAEWKLQAKVLKEQETVLQAQLTLYSGRFEEFQSTLTKSNEVFATFKQEMDKTTKKMKKLEKDTATWKARFENCNKALLDMIEEKALRAKEYECFVMKIQRLENLCRALQEERKELYKKIREAKMSEKEDQVQRTSEEEPEPSVSENEEVDAEEANSFQKAVENLATAFTILHHPEFTPDQPTERQLAVNGPQSGSDVTHQHPETARLNHPSLPADSGSPRPPVGAQAVAEGVCEATPAPTASCTPAEAELQSQGLPAENTPGPKPHKPEANTSGQAPLSPAQGSLSVVEAKYDISPSPESEGDSAVVPGCESREQPPPEVTDIPVGPSTGLPREPDACLNGVD", "length": 685 }, "evidence": [ { "id": "F1N4G3", "url": "https://omabrowser.org/oma/group/F1N4G3/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" } ], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 1, "go_terms": [ { "name": "cytoplasm", "id": "GO:0005737", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005737", "evidence": [ { "database": "UniProtKB", "id": "F1N4G3", "url": "https://www.uniprot.org/uniprotkb/F1N4G3" } ], "pmid": "" } ] }, { "name": "Molecular Function", "total": 1, "go_terms": [ { "name": "syntaxin binding", "id": "GO:0019905", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0019905", "evidence": [ { "database": "UniProtKB", "id": "F1N4G3", "url": "https://www.uniprot.org/uniprotkb/F1N4G3" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 230, "end_pos": 232, "annotation": "n_glycosylation_sequon" }, { "start_pos": 484, "end_pos": 486, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [ { "pdb_id": "AF-F1N4G3-F1", "pdb_chain": "global", "start_pos": 1, "end_pos": 738, "overlap": "1.0", "method": "AlphaFold", "type": "alphafold", "resolution": -1.0, "url": "https://data.glygen.org/ln2downloads/pdb/current/AF-F1N4G3-F1.pdb", "url_external": "https://alphafold.ebi.ac.uk/entry/F1N4G3" } ], "lectin_list": [], "domain_list": [], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "homologset.oma", "label": "OMA Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 230, "end_pos": 232 }, { "start_pos": 484, "end_pos": 486 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { 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"total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ], "tool_support": { "graph_view": "yes" } }, { "uniprot_canonical_ac": "F1N4G6-1", "uniprot_ac": "F1N4G6", "uniprot_id": "F1N4G6_BOVIN", "mass": { "chemical_mass": 34031.0, "monoisotopic_mass": 34031.0 }, "refseq": { "ac": "XP_059748330", "name": "transmembrane protein 255B", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_059748330" }, "gene_names": [ { "name": "TMEM255B", "type": "recommended", "evidence": [ { "id": "F1N4G6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1N4G6" } ] }, { "name": "TMEM255B", "type": "synonym", "evidence": [ { "id": "XP_059748330", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_059748330" } ] } ], "protein_names": [ { "name": "Transmembrane protein 255B", "type": "synonym", "evidence": [ { "id": "F1N4G6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1N4G6/entry#names_and_taxonomy" } ] }, { "name": "transmembrane protein 255B", "type": "synonym", "evidence": [ { "id": "XP_059748330", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_059748330" } ] } ], "function": [], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Bos taurus", "taxid": 9913, "evidence": [ { "database": 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"https://www.uniprot.org/uniprotkb/F1N4G6-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MQPLPPPVPGPLALLDTTEFVRRKKTALWFVGALLAVSASILTVGLAATTRTENVTVGGYYPGIILGFGSFLGIIGINLMENRKQMLVAAIVFVSFGVVAAFCCAVVDGVFAARHIEPRPLIAGRCQFHSSGAGYLHDVHQTEVTCHSPNGGCPLKVKSNTCYCCDLYDCQGTQSPPIYHEFVGVGACRDALQLYWLLWASAVLNVLGLLLGVITAAVLGAFKDVVPLAQLAYGPSMAPRVLYDPAQQILACSGFRPRPPAIPTCSSYPLPLQLPGAFAASRGSDLPLPEDSQPQPSSSCQHPLSAPTHLLPGEKPPPYTP", "length": 321, "header": "tr|F1N4G6-1|F1N4G6_BOVIN Isoform 1 of Transmembrane protein 255B OS=Bos taurus OX=9913 GN=TMEM255B PE=3 SV=4 CANONICAL=F1N4G6-1" }, "isoforms": [ { "isoform_ac": "F1N4G6-1", "url": "https://www.uniprot.org/uniprotkb/F1N4G6/entry", "sequence": { "sequence": "MQPLPPPVPGPLALLDTTEFVRRKKTALWFVGALLAVSASILTVGLAATTRTENVTVGGYYPGIILGFGSFLGIIGINLMENRKQMLVAAIVFVSFGVVAAFCCAVVDGVFAARHIEPRPLIAGRCQFHSSGAGYLHDVHQTEVTCHSPNGGCPLKVKSNTCYCCDLYDCQGTQSPPIYHEFVGVGACRDALQLYWLLWASAVLNVLGLLLGVITAAVLGAFKDVVPLAQLAYGPSMAPRVLYDPAQQILACSGFRPRPPAIPTCSSYPLPLQLPGAFAASRGSDLPLPEDSQPQPSSSCQHPLSAPTHLLPGEKPPPYTP", "length": 321, "header": "tr|F1N4G6-1|F1N4G6_BOVIN Isoform 1 of Transmembrane protein 255B OS=Bos taurus OX=9913 GN=TMEM255B PE=3 SV=4 CANONICAL=F1N4G6-1" }, "locus": { "chromosome": "12", "start_pos": 86801870, "end_pos": 86774179, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000026592.6", "url": "https://www.ensembl.org/id/ENSBTAT00000026592.6" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000026592.6", "url": "https://www.ensembl.org/id/ENSBTAP00000026592.6" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [ { "id": "bta:618499", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?bta:618499", "resource": "KEGG Pathway" } ], "orthologs": [], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 1, "go_terms": [ { "name": "membrane", "id": "GO:0016020", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016020", "evidence": [ { "database": "UniProtKB", "id": "F1N4G6", "url": "https://www.uniprot.org/uniprotkb/F1N4G6" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 54, "end_pos": 56, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [ { "pdb_id": "AF-F1N4G6-F1", "pdb_chain": "global", "start_pos": 1, "end_pos": 321, "overlap": "1.0", "method": "AlphaFold", "type": "alphafold", "resolution": -1.0, "url": "https://data.glygen.org/ln2downloads/pdb/current/AF-F1N4G6-F1.pdb", "url_external": "https://alphafold.ebi.ac.uk/entry/F1N4G6" } ], "lectin_list": [], "domain_list": [], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 54, "end_pos": 56 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": 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{ "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ], "tool_support": { "graph_view": "yes" } }, { "uniprot_canonical_ac": "F1N4I0-1", "uniprot_ac": "F1N4I0", "uniprot_id": "F1N4I0_BOVIN", "mass": { "chemical_mass": 192833.0, "monoisotopic_mass": 192833.0 }, "refseq": { "ac": "XP_024832494", "name": "zinc finger protein castor homolog 1 isoform X4", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_024832494" }, "gene_names": [ { "name": "CASZ1", "type": "recommended", "evidence": [ { "id": "F1N4I0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1N4I0" } ] }, { "name": "CASZ1", "type": "synonym", "evidence": [ { "id": "XP_024832494", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_024832494" } ] } ], "protein_names": [ { "name": "Castor zinc finger 1", "type": "synonym", "evidence": [ { "id": "F1N4I0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1N4I0/entry#names_and_taxonomy" } ] }, { "name": "zinc finger protein castor homolog 1 isoform X4", "type": "synonym", "evidence": [ { "id": "XP_024832494", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_024832494" } ] } ], "function": [], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Bos taurus", "taxid": 9913, "evidence": [ { "database": "UniProtKB", "id": "F1N4I0", "url": "https://www.uniprot.org/uniprotkb/F1N4I0" } ], "common_name": "Bovine", "glygen_name": "Bovine", "reference_species": "Bos taurus [9913]" } ], "gene": [ { "name": "CASZ1", "url": "https://www.uniprot.org/uniprotkb/F1N4I0", "locus": { 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"database": "Ensembl Peptide", "id": "ENSBTAP00000007151.6", "url": "https://www.ensembl.org/id/ENSBTAP00000007151.6" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [], "orthologs": [], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 2, "go_terms": [ { "name": "nucleus", "id": "GO:0005634", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005634", "evidence": [ { "database": "UniProtKB", "id": "F1N504", "url": "https://www.uniprot.org/uniprotkb/F1N504" } ], "pmid": "" }, { "name": "cytoplasm", "id": "GO:0005737", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005737", "evidence": [ { "database": "UniProtKB", "id": "F1N504", "url": "https://www.uniprot.org/uniprotkb/F1N504" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 1, "go_terms": [ { "name": "odontogenesis", "id": "GO:0042476", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0042476", "evidence": [ { "database": 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"http://www.pantherdb.org/panther/family.do?clsAccession=PTHR46105", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR46105:SF32", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR46105:SF32", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00096", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00096", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF00651", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00651", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF12874", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF12874", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "NP_001193201", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001193201", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "F1N518", "url": "https://www.uniprot.org/uniprotkb/F1N518", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "F1N518-1", "url": "https://www.uniprot.org/uniprotkb/F1N518-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MEKSGNIQLEIPDFSNSVLSHLNQLRMQGRLCDIVVNVQGQAFRAHKVVLAASSPYFRDHMSLNEMSTVSISVIKNPTVFEQLLSFCYTGRICLQLADIISYLTAASFLQMQHIIDKCTQILEGIHFKINVAEVEAELSQTRTKHAEGPPESHRVTPNLNRSLSPRHNTLKGNRRGQVSAVLDIRELSPPEESTSPQIIEQSSDVESREPILRINRAGQWYVETGVADRGARSDDEVRVLGAVHIKTENLEEWLGPENQPSGEDGSSAEEVTAMVIDTTGHGSVGQENYALGSSGAKVARPTSSEIDRFSPSGSVVPLTERHRARSESPGRMDEPKQPTSQVEESAMMGVSGYVEYLREQEVSERWFRYNPRLTCIYCAKSFNQKGSLDRHMRLHMGITPFVCRMCGKKYTRKDQLEYHIRKHTGNKPFHCHVCGKSFPFQAILNQHFRKNHPGCIPLEGPHSISPETTVTSRGQAEEESPSQEETVASGETAQGSVSTTGPD", "length": 503, "header": "tr|F1N518-1|F1N518_BOVIN Isoform 1 of Zinc finger and BTB domain containing 37 OS=Bos taurus OX=9913 GN=ZBTB37 PE=4 SV=2 CANONICAL=F1N518-1" }, "isoforms": [ { "isoform_ac": "F1N518-1", "url": "https://www.uniprot.org/uniprotkb/F1N518/entry", "sequence": { 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"https://www.ensembl.org/id/ENSBTAP00000038286.2" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [ { "id": "bta:617314", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?bta:617314", "resource": "KEGG Pathway" } ], "orthologs": [ { "uniprot_canonical_ac": "A0A061HYY6-1", "protein_name": "Zinc finger and BTB domain-containing protein 37 isoform X1", "gene_name": "Zbtb37", "tax_id": 10029, "organism": "Cricetulus griseus", "sequence": { "sequence": 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"MEKGGNIQLEIPDFSNSVLSHLNQLRMQGRLCDIVVNVQGQAFRAHKVVLAASSPYFRDHMSLNEMSTVSISVIKNPTVFEQLLSFCYTGRICLQLADIISYLTAASFLQMQHIIDKCTQILEGIHFKINVAEVEAELSQTRTKHPEGPPESHRVTPNLNRSLSPRHNTPKGNRRGQVSTVLDIRELSPPEESTSPQIIEQSSDVESREPILRINRAGQWYVETGVADRGARSDDEVRVLGAVHIKTENLEEWLGPENQPSGEDGSSAEEVTAMVIDTTGHGSVGQENYSLGSSGAKVARPTSSEIDRFSPSGSVVPLTERHRARSESPGRMDEPKQPSSQVEESAMMGVSGYVEYLREQEVSERWFRYNPRLTCIYCAKSFNQKGSLDRHMRLHMGITPFVCRMCGKKYTRKDQLEYHIRKHTGNKPFHCHVCGKSFPFQAILNQHFRKNHPGCIPLEGPHSISPETTVTSRGQAEEESPSQEETVASGETAPGSVSTTGPD", "length": 503 }, "evidence": [ { "id": "F1N518", "url": "https://omabrowser.org/oma/group/F1N518/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "A0A8V0YAS8-1", "protein_name": "Zinc finger and BTB domain containing 37", "gene_name": "ZBTB37", "tax_id": 9031, "organism": "Gallus gallus", "sequence": { "sequence": "MLPLTLQGCTPATETAMEKSGNIQLEIPDFSNSVLSHLNQLRMQGRLCDIVVNVQGQAFRAHKVVLAASSPYFRDHMSLNEMSTVSISVIKNPSVFEQLLSFCYTGRICLQLADIISYLTAASFLQMQHIIDKCTQILEGIHFKINVAEVEAELSQTRTKHQERPPESHRVTPNLNRSLSPRHNTLKGSRLGQVSTVLDIRELSPPAESTSPQIIEQSSDVESREPILRINRAGQWYVETGMGDRGGRNDDDVRVLGGVRIKTENLEEWLGTENQPSGEDGSSAEEVTAMVIDTTGHGSMSQETYALGSSGAKVARPTSSEIDRFSPSGSMVAVTERYRSKSESPGRMDEPKQPSSQGEESAMFGVSGYVEYLREQEVSERWFRYNPRLTCIYCAKSFNQKGSLDRHMRLHMGITPFVCRMCGKKYTRKDQLEYHIRKHTGNKPFHCHVCGKSFPFQAILNQHFRKNHPGCVPLEGPHSISPETTVTSRGQAEEESPPQEEAVAVGETAQGSVSTTGPD", "length": 519 }, "evidence": [ { "id": "F1N518", "url": "https://omabrowser.org/oma/group/F1N518/", "database": "OMA" } ], "glygen_name": "Chicken", "common_name": "Chicken" }, { "uniprot_canonical_ac": "D3ZGJ3-1", "protein_name": "Zinc finger and BTB domain containing 37", "gene_name": "Zbtb37", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": 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"UniProtKB", "id": "F1N518", "url": "https://www.uniprot.org/uniprotkb/F1N518" } ], "pmid": "" } ] }, { "name": "Molecular Function", "total": 3, "go_terms": [ { "name": "zinc ion binding", "id": "GO:0008270", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008270", "evidence": [ { "database": "UniProtKB", "id": "F1N518", "url": "https://www.uniprot.org/uniprotkb/F1N518" } ], "pmid": "" }, { "name": "DNA-binding transcription repressor activity, RNA polymerase II-specific", "id": "GO:0001227", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0001227", "evidence": [ { "database": "UniProtKB", "id": "F1N518", "url": "https://www.uniprot.org/uniprotkb/F1N518" } ], "pmid": "" }, { "name": "RNA polymerase II cis-regulatory region sequence-specific DNA binding", "id": "GO:0000978", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000978", "evidence": [ { "database": "UniProtKB", "id": "F1N518", "url": "https://www.uniprot.org/uniprotkb/F1N518" } ], "pmid": "" } ] } ] }, "pro_annotation": [], 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"sort_fields": [] } ], "tool_support": { "graph_view": "yes" } }, { "uniprot_canonical_ac": "F1N529-1", "uniprot_ac": "F1N529", "uniprot_id": "F1N529_BOVIN", "mass": { "chemical_mass": 44298.0, "monoisotopic_mass": 44298.0 }, "refseq": {}, "gene_names": [ { "name": "SERPINB2", "type": "recommended", "evidence": [ { "id": "F1N529", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1N529" } ] } ], "protein_names": [ { "name": "Serpin family B member 2", "type": "synonym", "evidence": [ { "id": "F1N529", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1N529/entry#names_and_taxonomy" } ] } ], "function": [], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Bos taurus", "taxid": 9913, "evidence": [ { "database": "UniProtKB", "id": "F1N529", "url": "https://www.uniprot.org/uniprotkb/F1N529" } ], "common_name": "Bovine", "glygen_name": "Bovine", "reference_species": "Bos taurus [9913]" } ], "gene": [ { "name": "SERPINB2", "url": "https://www.uniprot.org/uniprotkb/F1N529", "locus": {} } ], "crossref": [ { "id": "F1N529", "url": "https://alphafold.ebi.ac.uk/entry/F1N529", "database": "AlphaFoldDB", "categories": [] }, { "id": "ENSBTAG00000023198", "url": "https://bgee.org/?page=gene&gene_id=ENSBTAG00000023198", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "IPR000215", "url": "https://www.ebi.ac.uk/interpro/entry/IPR000215", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR023795", "url": "https://www.ebi.ac.uk/interpro/entry/IPR023795", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR023796", "url": "https://www.ebi.ac.uk/interpro/entry/IPR023796", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR036186", "url": "https://www.ebi.ac.uk/interpro/entry/IPR036186", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": 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"UniProtKB", "categories": [ "Protein" ] }, { "id": "F1N529-1", "url": "https://www.uniprot.org/uniprotkb/F1N529-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MEELYVANTIFALNFFKHLANTSANTQNLFFCPWSISSTMAMVYLGARGNTADQIAQVLQFNQVGVHRGTPVTPRSLSSCNFSQQIQRGTYPDAILQAQAAGVIHSSFHSLSNTINVSMGEYLLESANKLFGEKSARFKEEYMQLSKRYYSTEPQAVDFLECAEDARKQINSWVKTQTKGKIPNLLPEGSVDADTKMVLVNAIYFKGKWKTPFQKKLKGLYPFHVNSTQHKSVEMMFLHEKLNIGYIADLKVQILELPYAGELESEITPDKLSKWLSEDTMGEDDVEVYIPRFKLEERYGLKTILTGMGMGDAFSQGRANFSGMSEKNDLFLSEVFHQASVDVNEEGTEAAAGTGAIVTGRTGHGGPQFVADHPFLFFIVHKITKSILFWGRFASP", "length": 396, "header": "tr|F1N529-1|F1N529_BOVIN Isoform 1 of Serpin family B member 2 OS=Bos taurus OX=9913 GN=SERPINB2 PE=3 SV=2 CANONICAL=F1N529-1" }, "isoforms": [ { "isoform_ac": "F1N529-1", "url": "https://www.uniprot.org/uniprotkb/F1N529/entry", "sequence": { "sequence": 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"MVKEKKKADKKGDKSARSPSSPSDYPEFAKQDGNAPRQDASPSAAPALDVQPKDPGVKREVKSESLPNEDTTQYEEPVLTKLIVESYEGEKVRGLYEGEGFAIFQGGCTYQGMFSEGLMHGQGTYIWADGLKYEGDFVKNIPMNHGVFTWPDGSTYEGEVVGGMRHGFGMFKCSTQPVSYIGHWCHGKRHGKGSIYYNQEGTSWYEGDWIHNIRKGWGIRCYKSGNIYEGQWENNVRHGEGRMRWLTTNEEYTGQWKHGVQNGLGTHTWFLKRIPYSQYPLRNEYVGEFVNGYRHGHGKFYYASGAMYEGEWVSNKKHGMGRLTFKNGRVYDGPFSKDHMVAFPNLEGEVMSYPDSTSECAFGCQWCRPSASAEIMRKLDGNESNSLLGSSLELDLSLLLKMYPERDQSEEKKQVEYAILRNITELRRIYNFYSSLGCDRSLDNTFLMTKLHFWRFLKDCKFHHHNITLADMDRVLGANNNIPVEEIHSPFTTLLLRTFLNYLLQLAYHIHHKEYQDRSPSLFLCFKKLMNENIRPNACRVKGRLFCEAQRTLYSMTYVDKCWEIYTAHCRPNAAPPHELTMSTRHFLWMLRSFKMINKELTATKFVEVIAEDNPSMYDGIDSNFELELVFLEFFEALLSFALICVPEPPTKFCSDFPNDDLSVNKAGSTYPVTAQNTQNRSPSAVASQESDIQFSSTKSSSSKLGVLVDISKIRKSEPKIKKSVSDGKTSKVNFKSAGKGLTFLLSQSGKKEKHKDEQKEKFNIWISNMYVFFVNTLFQAHKHEETLKEKVKENRLHNEAMALQRKMENEELEARLNSLREEEAKRQDYEVDITVIKEPVDAPSSSFTPSPPKEDTVVSSKSITSKKKKK", "length": 871, "header": "tr|F1N5C9-1|F1N5C9_BOVIN Isoform 1 of Radial spoke head 10 homolog B (Chlamydomonas) OS=Bos taurus OX=9913 GN=RSPH10B PE=4 SV=1 CANONICAL=F1N5C9-1" }, "locus": { "chromosome": "25", "start_pos": 38004130, "end_pos": 37981097, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000007760.6", "url": "https://www.ensembl.org/id/ENSBTAT00000007760.6" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000007760.5", "url": "https://www.ensembl.org/id/ENSBTAP00000007760.5" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [ { "id": "bta:510922", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?bta:510922", "resource": "KEGG Pathway" } ], "orthologs": [ { "uniprot_canonical_ac": "A0A8V0ZMM2-1", "protein_name": "Radial spoke head 10 homolog B", "gene_name": "RSPH10B", "tax_id": 9031, "organism": "Gallus gallus", "sequence": { "sequence": "MAKDKKKDGKKSEKPTHPAPAPSAAAESSPTELTGLHASADEVEEAQASAAESDKEIEKAEGPPGQQDVPPYYQEPILTQLIVKSYEGDKVRRLYEGEGVAFFEGGNIYKGMFSEGFMHGQGTYTWADGVKYEGTFVKNVQMFHGYYMWNDGSIYEGSVKNGLRHGFGFFRSGIHPVSYIGYWYKGKRHGKGTIYYDQEHMSWYSGDWVDNVKEGWGIRCYKSGNTYEGHWEKNVRHGKGRMRWLTADQEYVGQWVYGVQHGYGTHVWFLKRMPASQYPLRNKYMGDFVNGERHGRGKFIYASGAVYDGEWAHNKKHGKGKFVFKNGSIYEGEFRGDKMVECPSFQLDAVSAPKLNAICSGSCSGSETIRIINNSENPSALGSDIELDISSLLNLLPREERQEEVKQVEFAVLRHITKLRGVYTFYSSLGCNDSPDNTFLMTRLQFWRFLKDCCFHHSSMTLAEMDRMLSGDKTPLEEIHSPYETLLFRTFLSHLIHLSFHIYHEEYKDKGLYLHKCFTEMMSRNVIPTACHVQGLLFSEQHRAVFAMRYIDKCWEIYRAFCRQNARPPFEPTMKMRQFLWMLNDFKLLGKQLTAARLVEILFKDGPSLHDSNSSNLEQELVFLEFVEALLHCALVYVTSDVIKEQVDRDNQKRSSFRMEGFSEGTANVPFYTQYSPSQVLRPCEDRGQTLQEFLMGSVQSSHTTHGSVKDVRPLSSWDAEKEQDFSPTSELIDELEAQTGKDKEFDWWMYQVQIFFTNKFFPAYHHEKVLKAKIKENQIRNAELAELRRKKDEEIAKLIAEREAEDAKKQKEAAEEEVSLESKSTVFKELEEPGAQLAPPPKEEASAVPPPAVTKVPTGTKRRRK", "length": 866 }, "evidence": [ { "id": "F1N5C9", "url": "https://omabrowser.org/oma/group/F1N5C9/", "database": "OMA" } ], "glygen_name": "Chicken", "common_name": "Chicken" }, { "uniprot_canonical_ac": "B2RC85-1", "protein_name": "Radial spoke head 10 homolog B2", "gene_name": "RSPH10B2", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MVKEKKKADKKGEKSARSPSSLSDNLDFSKQDGNTTRQEMSPAGVPLLGMQLNEVKPKKDRQNVQQNEDASQYEESILTKLIVESYEGEKVRGLYEGEGFAAFQGGCTYRGMFSEGLMHGQGTYIWADGLKYEGDFVKNVPMNHGVYTWPDGSMYEGEVVNGMRNGFGMFKCSTQPVSYIGHWCNGKRHGKGSIYYNQEGTCWYEGDWVQNIKKGWGIRCYKSGNIYEGQWEDNMRHGEGRMRWLTTNEEYTGRWERGIQNGFGTHTWFLKRIRSSQYPLRNEYIGEFVNGYRHGRGKFYYASGAMYDGEWVSNKKHGMGRLTFKNGRVYEGAFSNDHIAGFPDLEVEFISCLDLSSGVAPRLSRSAELIRKLDGSESHSVLGSSIELDLNLLLDMYPETVQPEEKKQVEYAVLRNITELRRIYSFYSSLGCGHSLDNTFLMTKLHFWRFLKDCKFHHHKLTLADMDRILSANNDIPVEEIHSPFTTILLRTFLNYLLHLAYHIYHEEFQKRSPSLFLCFTKLMTENIRPNACQIKGNLFREQQRTLYSMSYMNKCWEIYLAYCRPSAAPPHEPTMKMRHFLWMLKDFKMINKELTAATFMEVIAEDNRFIYDGIDSNFEPELVFLEFFEALLSFAFICVTDQMTKSYTNVPADDVSGNKHETIYTILNQDAQNKSPSAVMSHESDAAHSDSARSSSSKLELSPDVNKIRKSEPKIKKSVSHERVSKMNFKLTGKGITFFSSESKKYERPKDDREEEFNTWVNNTYVFFVNTLFHAYKREEAIKEKIRADRLRSTAQAQQRKMEDDELEARLNIFILREEEAKRHDYEVDITVLKEPADVSSSHLILDPPKEDVTVSPSSKTITSKKKKK", "length": 870 }, "evidence": [ { "id": "F1N5C9", "url": "https://omabrowser.org/oma/group/F1N5C9/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "E9PYQ0-1", "protein_name": "Radial spoke head 10 homolog B", "gene_name": "Rsph10b", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MVKEKKKADKKGDKSARSPSSISDNPEASKQDSNASKQEVAPSAVVPVVETPLKQAPKRDSVQMEQSEEETQYEEPILTKLIVESYEGEKVRGLYEGEGFAVFQGGNTYHGMFSEGLMHGQGTYIWADGLKYEGDFVKNIPMNHGVYTWPDGSTYEGEVTNGMRNGFGMFKCGTQPVSYIGHWCHGKRHGKGSIYYNQEGTSWYEGDWVYNIKKGWGIRCYKSGNIYEGQWENNMRHGEGRMRWLTTNEEYTGHWEKGIQNGFGTHTWFLKRIPNSQYPLRNEYIGEFVNGFRHGQGKFYYASGAMYEGEWASNKKQGRGRMTFKNGHVYEGLFSNDHIAQFFETEMDYSQSLDRWSDASQRSRQPRGSSVSAVREPETLRKLDGSESRSVLGTSIELDLTLLLDMYPEESQEEEKKQVEYAVLRNITELRRIYCFYSGLGCDHSLDNTFLMTKLHFWRFLKDCRFHHHNITLADMDRVLSVYNGIPIEEIHSPFRTILLRTFLNYLLQLAYYIHHKEFQNRSPSLFLCFTKLMSENIHPHACQVKGHLFSEQQRTLYSMNYIDKCWEIYTAYCRPNEAPPYELTMKMRYFLWMLKDFRMINKDLTATKFMTVIAEDNPFVYDGTDSNFELELVFLEFFEALLCFSLCCMFDQMTRSYLKVPYDDITTNRYGSTQTILNQSIHRSPSAITSHDSEVHFSSTKSSLDKIGALPDGKIRQSEPKLKKSLSEDKVSKMNFKTQGRGLVFMSPQGEKYEKPKDEQKEKLNIWVNNLYVFFVSVLFSAYKREEMLKEKVKENQLQEAELAQQRQIENEELEARLNILREEEARKQDFELDITVLKEPSEIPASQPLTPSPPKEDLASIQTSKASPGKKKKK", "length": 876 }, "evidence": [ { "id": "F1N5C9", "url": "https://omabrowser.org/oma/group/F1N5C9/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "P0C881-1", "protein_name": "Radial spoke head 10 homolog B", "gene_name": "RSPH10B", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MVKEKKKADKKGEKSARSPSSLSDNLDFSKQDGNTTRQEMSPAGVPLLGMQLNEVKPKKDRQNVQQNEDATQYEESILTKLIVESYEGEKVRGLYEGEGFAAFQGGCTYRGMFSEGLMHGQGTYIWADGLKYEGDFVKNVPMNHGVYTWPDGSMYEGEVVNGMRNGFGMFKCSTQPVSYIGHWCNGKRHGKGSIYYNQEGTCWYEGDWVQNIKKGWGIRCYKSGNIYEGQWEDNMRHGEGRMRWLTTNEEYTGRWERGIQNGFGTHTWFLKRIRSSQYPLRNEYIGEFVNGYRHGRGKFYYASGAMYDGEWVSNKKHGMGRLTFKNGRVYEGAFSNDHIAGFPDLEVEFISCLDLSSGVAPRLSRSAELIRKLDGSESHSVLGSSIELDLNLLLDMYPETVQPEEKKQVEYAVLRNITELRRIYSFYSSLGCGHSLDNTFLMTKLHFWRFLKDCKFHHHKLTLADMDRILSANNDIPVEEIHSPFTTILLRTFLNYLLHLAYHIYHEEFQKRSPSLFLCFTKLMTENIRPNAFQIKGNLFREQQRTLYSMSYMNKCWEIYLAYCRPSAAPPHEPTMKMRHFLWMLKDFKMINKELTAATFMEVIAEDNRFIYDGIDSNFEPELVFLEFFEALLSFAFICVTDQMTKSYTNVPADDVSGNKHETIYTILNQDAQNKSPSAVMSHESDAAHSDSARSSSSKLELSPDVNKIRKSEPKIKKSVSHERVSKMNFKLTGKGITFFSSESKKYERPKDDREEEFNTWVNNMYVFFVNTLFHAYKREEAIKEKIRADRLRSTAQAQQRKMEDDELEARLNIFILREEEAKRHDYEVDITVLKEPADVSSSHLILDPPKEDVTVSPSSKTITSKKKKK", "length": 870 }, "evidence": [ { "id": "F1N5C9", "url": "https://omabrowser.org/oma/group/F1N5C9/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "Q66HB5-1", "protein_name": "Radial spoke head 10 homolog B", "gene_name": "Rsph10b", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MVKEKKKADKKGDKSARSPSSISDNPEAAKQEISASKQEVAPSAVIPVLETPLKQTPKRDSEHTYQSEDETQYEEPILTKLIVESYEGEKVRGLYEGEGFAVFQGGNTYHGMFSEGLMHGQGTYIWADGLKYEGDFVKNIPMNHGVYTWPDGSTYEGEVVNGMRNGFGMFKCGTQPVSYIGHWCHGKRHGKGSIYYNQEGTSWYEGDWVYNIKKGWGIRCYKSGNIYEGQWENNMRHGEGRMRWLTTNEEYTGHWEKGIQNGFGTHTWFLKRIPNSQYPLRNEYIGAFVNGFRHGQGKFYYASGAMYEGEWVSNKKQGRGRITFKNGRVYEGLFSNDHIAQFFEAEMDYSYSLDRRSDISQRSRQARGSSVSADREPETLRKLDGSESRSVLGSSIELDLNLLLDMYPEESQEEEKKQVEYAVLRNITELRRIYCFYSGLGCDHSLDNTFLMTKLHFWRFLKDCRFHHHNITLADMDRVLSVYNGIPIEEIHSPFRTILLRTFLNYLLQLAYYIHHKEFQNRSPSLFLCFTKLMAENIHPHACQVKGHLFNEQQRTLYSMNYIDKCWEIYTAYCRPNEAPPYELTMKMRYFLWMLKDFRMINKELTATKFMRVIAEDNPFVYDGMDSNFELELVFLEFFEALLCFSLCCMFDQMTRSYLKAPYDDVTTNRYGSTQTVLNQSIHRSPSGATSHDSEVHFSSTKSSLDKIGVLPDGKIRQSEPKLKKSLSEDKVSKMNLKAQGRGLVFMSPHGEKYEKSKDEQKEKLNMWVNNLYVFFVSVLFSAYKHEEALKEKVEENRLQEAVLAQQKQIENEELEARLNILREEEARRQDFELDITVLKEPPEVPAVQPLTPSPPKEDLVSMQTSKASPGKKKKK", "length": 876 }, "evidence": [ { "id": "F1N5C9", "url": "https://omabrowser.org/oma/group/F1N5C9/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" } ], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 2, "go_terms": [ { "name": "axoneme", "id": "GO:0005930", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005930", "evidence": [ { "database": "UniProtKB", "id": "F1N5C9", "url": "https://www.uniprot.org/uniprotkb/F1N5C9" } ], "pmid": "" }, { "name": "9+2 motile cilium", "id": "GO:0097729", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0097729", "evidence": [ { "database": "UniProtKB", "id": "F1N5C9", "url": "https://www.uniprot.org/uniprotkb/F1N5C9" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 382, "end_pos": 384, "annotation": "n_glycosylation_sequon" }, { "start_pos": 422, "end_pos": 424, "annotation": "n_glycosylation_sequon" }, { "start_pos": 466, "end_pos": 468, "annotation": "n_glycosylation_sequon" }, { "start_pos": 680, "end_pos": 682, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [ { "pdb_id": "AF-F1N5C9-F1", "pdb_chain": "global", "start_pos": 1, "end_pos": 871, "overlap": "1.0", "method": "AlphaFold", "type": "alphafold", "resolution": -1.0, "url": "https://data.glygen.org/ln2downloads/pdb/current/AF-F1N5C9-F1.pdb", "url_external": "https://alphafold.ebi.ac.uk/entry/F1N5C9" } ], "lectin_list": [], "domain_list": [], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "homologset.oma", "label": "OMA Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 382, "end_pos": 384 }, { "start_pos": 422, "end_pos": 424 }, { "start_pos": 466, "end_pos": 468 }, { "start_pos": 680, "end_pos": 682 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ], "tool_support": { "graph_view": "yes" } }, { "uniprot_canonical_ac": "F1N5F0-1", "uniprot_ac": "F1N5F0", "uniprot_id": "F1N5F0_BOVIN", "mass": { "chemical_mass": 144953.0, "monoisotopic_mass": 144953.0 }, "refseq": {}, "gene_names": [ { "name": "OVCH1", "type": "recommended", "evidence": [ { "id": "F1N5F0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1N5F0" } ] } ], "protein_names": [ { "name": "Granzyme M", "type": "recommended", "evidence": [ { "id": "F1N5F0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1N5F0/entry#names_and_taxonomy" } ] }, { "name": "Met-ase", "type": "synonym", "evidence": [ { "id": "F1N5F0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1N5F0/entry#names_and_taxonomy" } ] }, { "name": "Natural killer cell granular protease", "type": "synonym", "evidence": [ { "id": "F1N5F0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1N5F0/entry#names_and_taxonomy" } ] } ], "function": [ { "annotation": "Cleaves peptide substrates after methionine, leucine, and norleucine. Physiological substrates include EZR, alpha-tubulins and the apoptosis inhibitor BIRC5/Survivin. Promotes caspase activation and subsequent apoptosis of target cells.", "evidence": [ { "database": "UniProtKB", "id": "F1N5F0", "url": "https://www.uniprot.org/uniprotkb/F1N5F0#function" }, { "database": "UniProtKB", "id": "ARBA00054080", "url": "https://www.uniprot.org/uniprotkb/ARBA00054080#function" }, { "database": "UniProtKB", "id": "A0ABI0NMH7", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NMH7#function" }, { "database": "UniProtKB", "id": "A0ABI0NRP0", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NRP0#function" }, { "database": "UniProtKB", "id": "A0ABI0NT19", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NT19#function" }, { "database": "UniProtKB", "id": "A0ABI0P0M4", "url": "https://www.uniprot.org/uniprotkb/A0ABI0P0M4#function" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Bos taurus", "taxid": 9913, "evidence": [ { "database": "UniProtKB", "id": "F1N5F0", "url": "https://www.uniprot.org/uniprotkb/F1N5F0" } ], "common_name": "Bovine", "glygen_name": "Bovine", "reference_species": "Bos taurus [9913]" } ], "gene": [ { "name": "OVCH1", "url": "https://www.uniprot.org/uniprotkb/F1N5F0", "locus": { "chromosome": "5", "start_pos": 80217676, "end_pos": 80123570, "strand": "-", "evidence": [ { "database": "Ensembl Gene", "id": "ENSBTAG00000005365", "url": "https://www.ensembl.org/id/ENSBTAG00000005365" } ] } } ], "crossref": [ { "id": "F1N5F0", "url": "https://alphafold.ebi.ac.uk/entry/F1N5F0", "database": "AlphaFoldDB", "categories": [] }, { "id": "ENSBTAG00000005365", "url": "https://bgee.org/?page=gene&gene_id=ENSBTAG00000005365", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "cd00041", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd00041", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "cd00190", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd00190", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "IPR000859", "url": "https://www.ebi.ac.uk/interpro/entry/IPR000859", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR001254", "url": "https://www.ebi.ac.uk/interpro/entry/IPR001254", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR001314", "url": "https://www.ebi.ac.uk/interpro/entry/IPR001314", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR009003", "url": "https://www.ebi.ac.uk/interpro/entry/IPR009003", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR018114", "url": "https://www.ebi.ac.uk/interpro/entry/IPR018114", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR033116", "url": "https://www.ebi.ac.uk/interpro/entry/IPR033116", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR035914", "url": "https://www.ebi.ac.uk/interpro/entry/IPR035914", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR043504", "url": "https://www.ebi.ac.uk/interpro/entry/IPR043504", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "PTHR24250", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR24250", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR24250:SF65", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR24250:SF65", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR24252", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR24252", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR24252:SF18", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR24252:SF18", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR24252:SF7", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR24252:SF7", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00089", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00089", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF00431", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00431", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "A0ABI0NMH7", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NMH7", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0ABI0NMH7-1", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NMH7-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0ABI0NRP0", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NRP0", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0ABI0NRP0-1", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NRP0-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0ABI0NT19", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NT19", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0ABI0NT19-1", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NT19-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0ABI0P0M4", "url": "https://www.uniprot.org/uniprotkb/A0ABI0P0M4", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0ABI0P0M4-1", "url": "https://www.uniprot.org/uniprotkb/A0ABI0P0M4-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "F1N5F0", "url": "https://www.uniprot.org/uniprotkb/F1N5F0", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "F1N5F0-1", "url": "https://www.uniprot.org/uniprotkb/F1N5F0-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "G3MX30", "url": "https://www.uniprot.org/uniprotkb/G3MX30", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "G3MX30-1", "url": "https://www.uniprot.org/uniprotkb/G3MX30-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MDRSPRMGAIRALPGAVSLLLLLLLAVHSPPSRGLKYGIHAVDLKSIETVLESRFFSRISSWRNSTVGGHPWQVSLKLGGHHFCGGSLIQDDLVVTAVHCLIGLNEKQIKSLTVTAGEYNLFQKDKEEQNIPVSKIIIHPEYNRLGYMSFNIALLYLKLKVKFGTTVQPICIPHRGDKFEEGIFCMASGWGKISETSEYSNILQEVEVPIMDDRRCGAMLRGMNLPPLGRDMLCASFPDGEKDACQRDSGGPLVCRRDDGVWVLAGITSWAAGCTRVWNPFRNKQRKASPGIFSKVFVLMDFITQTMTDSLNKIGSTSFPKTNPRSSAKVIPYGVCGIPPFSPQWLSRRIAGGVEACPHCWPWQVGLRFLGNHQCGGAIINSIWILTAAHCVQSKNNPLFWTIVAGDHDITLKESTEQVRRAKHIVMHEDFDSLSYDSDIALIQLSSALEFNSVVRPVCLPHSLEPLFSSEICVVTGWGSANKDGGLASRLQQIQVPVLEREVCERTYYSAHPGGISEKMICAGFAASGEKDVGQGDSGGLLVCKHEKGPFVLYGIVSWGAGCDQPRKPGVFARVSVFLDWIQSKIKDAGPVLLQIKNESKILTRQQLPPPTPSRDSASGPGCYSEVELEEPRGFFSSPRYPLDYRGKLECSWVLRVSPSSMAKFTVEYLLLPWSHMCQDSALIIYEENHSERRMSGKLCGRRLYPMVFMSSGPLVRVTFHSSVQGAFGINYIVFRVQGPKGSKSTQSLQSSNQEHVATCEDVILTKPAGIIQFPRNFHRTIMSCHWRLLAPINHIIRLDIISFQKQPMPLACQGDLWVYEGFGSGKKLIGNLCEGDSPSLKSHGPLMMLIFTYNASLAMKEFSLRYSFHMSGSMRGNIKVNGKEDKGGCPILDLIAVSSFEITSPNYPNIYPNMLNCTWTFYSISGNKMKALIKDFIMEESWNCEWDYFNIYDGPDQQSRLLAHLCGSKKEFVWISSGAYLTVNLKTDESVGERGFKLILEDMTQKPSQKSNIGIQLPINGLPVENNTRRQPAQDSCGVPFVDPFLIEGFERNTNILPAEVGEPRVVGGRAAAVMSWPWLVSLQHQGHHYCGGALIGRRWVLTAAHCNFSTVTDYLVIGRSYLGNIRNSDLIPVKAVYIHPSFTQFPPNDDLSLLHLEKPVELGEFVSTICLPGKDDKINLLSKCLTAGWGITEPHQDEFPKTVQQAKVPLISSISCRSYWGLEIKNTNICGGASGSSSCMGDSGGPLQCGEGGQYKLIGIVSWGSSNCHPAAPTVFTRISAYTDWITSITGGEAGSLGDQPGGTVITSGKGNT", "length": 1315, "header": "tr|F1N5F0-1|F1N5F0_BOVIN Isoform 1 of Granzyme M OS=Bos taurus OX=9913 GN=OVCH1 PE=4 SV=4 CANONICAL=F1N5F0-1" }, "isoforms": [ { "isoform_ac": "A0ABI0NMH7-1", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NMH7/entry", "sequence": { "sequence": "MAKFTVEYLLLPWSHMCQDSALIIYEENHSERRMSGKLCGRRLYPMVFMSSGPLVRVTFHSSVQGAFGINYIVFRVQGPKGSKSTQSLQSSNQEHVATCEDVILTKPAGIIQFPRNFHRTIMSCHWRLLAPINHIIRLDIISFQKQPMPLACQGDLWVYEGFGSGKKLIGNLCEGDSPSLKSHGPLMMLIFTYNASLAMKEFSLRYSFHMSAHLCGSKKEFVWISSGAYLTVNLKTDESVGERGFKLILEDMTQKPSQKSNIGIQLPINGLPVENNTRRQPAQDSCGVPFVDPFLIEGFERNTNILPAEVGEPRVVGGRAAAVMSWPWLVSLQHQGHHYCGGALIGRRWVLTAAHCNFSTVTDYLVIGRSYLGNIRNSDLIPVKAVYIHPSFTQFPPNDDLSLLHLEKPVELGEFVSTICLPGKDDKINLLSKCLTAGWGITEPHQDEFPKTVQQAKVPLISSISCRSYWGLEIKNTNICGGASGSSSCMGDSGGPLQCGEGGQYKLIGIVSWGSSNCHPAAPTVFTRISAYTDWITSITGGEAGSLGDQPGGTVITSGKGNT", "length": 563, "header": "tr|A0ABI0NMH7-1|A0ABI0NMH7_BOVIN Computationally mapped isoform of Granzyme M OS=Bos taurus OX=9913 GN=OVCH1 PE=4 SV=1 CANONICAL=F1N5F0-1" }, "locus": { "chromosome": "5", "start_pos": 80217298, "end_pos": 80175212, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000144165.1", "url": "https://www.ensembl.org/id/ENSBTAT00000144165.1" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000106639.1", "url": "https://www.ensembl.org/id/ENSBTAP00000106639.1" } ] } }, { "isoform_ac": "A0ABI0NRP0-1", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NRP0/entry", "sequence": { "sequence": "MDRSPRMGAIRALPGAVSLLLLLLLAVHSPPSRGLKYGIHAVDLKSIETVLESRFFSRISSWRNSTVGGHPWQVSLKLGGHHFCGGSLIQDDLVVTAVHCLIGLNEKQIKSLTVTAGEYNLFQKDKEEQNIPVSKIIIHPEYNRLGYMSFNIALLYLKLKVKFGTTVQPICIPHRGDKFEEGIFCMASGWGKISETSEYSNILQEVEVPIMDDRRCGAMLRGMNLPPLGRDMLCASFPDGEKDACQRDSGGPLVCRRDDGVWVLAGITSWAAGCTRVWNPFRNKQRKASPGIFSKVFVLMDFITQTMTDSLNKIGSTSFPKTNPRSSAKVIPYGVCGIPPFSPQWLSRRIAGGVEACPHCWPWQVGLRFLGNHQCGGAIINSIWILTAAHCVQSKNNPLFWTIVAGDHDITLKESTEQVRRAKHIVMHEDFDSLSYDSDIALIQLSSALEFNSVVRPVCLPHSLEPLFSSEICVVTGWGSANKDGGLASRLQQIQVPVLEREVCERTYYSAHPGGISEKMICAGFAASGEKDVGQGDSGGLLVCKHEKGPFVLYGIVSWGAGCDQPRKPGVFARVSVFLDWIQSKIKDAGPVLLQIKNESKILTRQQLPPPTPSRDSASGPGCYSEVELEEPRGFFSSPRYPLDYRGKLECSWVLRVSPSSMAKFTVEYLLLPWSHMCQDSALIIYEENHSERRMSGKLCGRRLYPMVFMSSGPLVRVTFHSSVQGAFGINYIVFRVQGPKGSKSTQSLQSSNQEHVATCEDVILTKPAGIIQFPRNFHRTIMSCHWRLLAPINHIIRLDIISFQKQPMPLACQGDLWVYEGFGSGKKLIGSMRGNIKVNGKEDKGGCPILDLIAVSSFEITSPNYPNIYPNMLNCTWTFYSISGNKMKALIKDFIMEESWNCEWDYFNIYDGPDQQSRLLAHLCGSKKEFVWISSGAYLTVNLKTDESVGERGFKLILEDMTQKPSQKSNIGIQLPINGLPVENNTRRQPAQDSCGVPFVDPFLIEGFERNTNILPAEVGEPRVVGGRAAAVMSWPWLVSLQHQGHHYCGGALIGRRWVLTAAHCNFSTVTDYLVIGRSYLGNIRNSDLIPVKAVYIHPSFTQFPPNDDLSLLHLEKPVELGEFVSTICLPGKDDKINLLSKCLTAGWGITEPHQDEFPKTVQQAKVPLISSISCRSYWGLEIKNTNICGGASGSSSCMGDSGGPLQCGEGGQYKLIGIVSWGSSNCHPAAPTVFTRISAYTDWITSITGGEAGSLGDQPGGTVITSGKGNT", "length": 1273, "header": "tr|A0ABI0NRP0-1|A0ABI0NRP0_BOVIN Computationally mapped isoform of Granzyme M OS=Bos taurus OX=9913 GN=OVCH1 PE=4 SV=1 CANONICAL=F1N5F0-1" }, "locus": { "chromosome": "5", "start_pos": 80217298, "end_pos": 80123789, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000140934.1", "url": "https://www.ensembl.org/id/ENSBTAT00000140934.1" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000106397.1", "url": "https://www.ensembl.org/id/ENSBTAP00000106397.1" } ] } }, { "isoform_ac": "A0ABI0NT19-1", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NT19/entry", "sequence": { "sequence": "MTQKPSQKSNIGIQLPINGLPVENNTRRQPAQDSCGVPFVDPFLIEGFERNTNILPAEVGEPRVVGGRAAAVMSWPWLVSLQHQGHHYCGGALIGRRWVLTAAHCNFSTVTDYLVIGRSYLGNIRNSDLIPVKAVYIHPSFTQFPPNDDLSLLHLEKPVELGEFVSTICLPGKDDKINLLSKCLTAGWGITEPHQDEFPKTVQQAKVPLISSISCRSYWGLEIKNTNICGGASGSSSCMGDSGGPLQCGEGGQYKLIGIVSWGSSNCHPAAPTVFTRISAYTDWITSITGGEAGSLGDQPGGTVITSGKGNT", "length": 312, "header": "tr|A0ABI0NT19-1|A0ABI0NT19_BOVIN Computationally mapped isoform of Granzyme M OS=Bos taurus OX=9913 GN=OVCH1 PE=4 SV=1 CANONICAL=F1N5F0-1" }, "locus": { "chromosome": "5", "start_pos": 80217298, "end_pos": 80207447, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000137516.1", "url": "https://www.ensembl.org/id/ENSBTAT00000137516.1" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000106442.1", "url": "https://www.ensembl.org/id/ENSBTAP00000106442.1" } ] } }, { "isoform_ac": "A0ABI0P0M4-1", "url": "https://www.uniprot.org/uniprotkb/A0ABI0P0M4/entry", "sequence": { "sequence": "MFLGPPSFTKQYGKIYSKLCGRRLYPMVFMSSGPLVRVTFHSSVQGAFGINYIVFRVQGPKGSKSTQSLQSSNQEHVATCEDVILTKPAGIIQFPRNFHRTIMSCHWRLLAPINHIIRLDIISFQKQPMPLACQGDLWVYEGFGSGKKLIGNLCEGDSPSLKSHGPLMMLIFTYNASLAMKEFSLRYSFHMSGSMRGNIKVNGKEDKGGCPILDLIAVSSFEITSPNYPNIYPNMLNCTWTFYSISGNKMKALIKDFIMEESWNCEWDYFNIYDGPDQQSRLLAHLCGSKKEFVWISSGAYLTVNLKTDESVGERGFKLILEDMTQKPSQKSNIGIQLPINGLPVENNTRRQPAQDSCGVPFVDPFLIEGFERNTNILPAEVGEPRVVGGRAAAVMSWPWLVSLQHQGHHYCGGALIGRRWVLTAAHCNFSTVTDYLVIGRSYLGNIRNSDLIPVKAVYIHPSFTQFPPNDDLSLLHLEKPVELGEFVSTICLPGKDDKINLLSKCLTAGWGITEPHHEFPKTVQQAKVPLISSISCRSYWGLEIKNTNICGGASGSSSCMGDSGGPLQCGEGGQYKLIGIVSWGSSNCHPAAPTVFTRISAYTDWITSITGGEAGSLGDQPGGTVITSGKGNT", "length": 634, "header": "tr|A0ABI0P0M4-1|A0ABI0P0M4_BOVIN Computationally mapped isoform of Granzyme M OS=Bos taurus OX=9913 GN=OVCH1 PE=4 SV=1 CANONICAL=F1N5F0-1" }, "locus": { "chromosome": "5", "start_pos": 80217298, "end_pos": 80175178, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000142475.1", "url": "https://www.ensembl.org/id/ENSBTAT00000142475.1" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000107705.1", "url": "https://www.ensembl.org/id/ENSBTAP00000107705.1" } ] } }, { "isoform_ac": "F1N5F0-1", "url": "https://www.uniprot.org/uniprotkb/F1N5F0/entry", "sequence": { "sequence": "MDRSPRMGAIRALPGAVSLLLLLLLAVHSPPSRGLKYGIHAVDLKSIETVLESRFFSRISSWRNSTVGGHPWQVSLKLGGHHFCGGSLIQDDLVVTAVHCLIGLNEKQIKSLTVTAGEYNLFQKDKEEQNIPVSKIIIHPEYNRLGYMSFNIALLYLKLKVKFGTTVQPICIPHRGDKFEEGIFCMASGWGKISETSEYSNILQEVEVPIMDDRRCGAMLRGMNLPPLGRDMLCASFPDGEKDACQRDSGGPLVCRRDDGVWVLAGITSWAAGCTRVWNPFRNKQRKASPGIFSKVFVLMDFITQTMTDSLNKIGSTSFPKTNPRSSAKVIPYGVCGIPPFSPQWLSRRIAGGVEACPHCWPWQVGLRFLGNHQCGGAIINSIWILTAAHCVQSKNNPLFWTIVAGDHDITLKESTEQVRRAKHIVMHEDFDSLSYDSDIALIQLSSALEFNSVVRPVCLPHSLEPLFSSEICVVTGWGSANKDGGLASRLQQIQVPVLEREVCERTYYSAHPGGISEKMICAGFAASGEKDVGQGDSGGLLVCKHEKGPFVLYGIVSWGAGCDQPRKPGVFARVSVFLDWIQSKIKDAGPVLLQIKNESKILTRQQLPPPTPSRDSASGPGCYSEVELEEPRGFFSSPRYPLDYRGKLECSWVLRVSPSSMAKFTVEYLLLPWSHMCQDSALIIYEENHSERRMSGKLCGRRLYPMVFMSSGPLVRVTFHSSVQGAFGINYIVFRVQGPKGSKSTQSLQSSNQEHVATCEDVILTKPAGIIQFPRNFHRTIMSCHWRLLAPINHIIRLDIISFQKQPMPLACQGDLWVYEGFGSGKKLIGNLCEGDSPSLKSHGPLMMLIFTYNASLAMKEFSLRYSFHMSGSMRGNIKVNGKEDKGGCPILDLIAVSSFEITSPNYPNIYPNMLNCTWTFYSISGNKMKALIKDFIMEESWNCEWDYFNIYDGPDQQSRLLAHLCGSKKEFVWISSGAYLTVNLKTDESVGERGFKLILEDMTQKPSQKSNIGIQLPINGLPVENNTRRQPAQDSCGVPFVDPFLIEGFERNTNILPAEVGEPRVVGGRAAAVMSWPWLVSLQHQGHHYCGGALIGRRWVLTAAHCNFSTVTDYLVIGRSYLGNIRNSDLIPVKAVYIHPSFTQFPPNDDLSLLHLEKPVELGEFVSTICLPGKDDKINLLSKCLTAGWGITEPHQDEFPKTVQQAKVPLISSISCRSYWGLEIKNTNICGGASGSSSCMGDSGGPLQCGEGGQYKLIGIVSWGSSNCHPAAPTVFTRISAYTDWITSITGGEAGSLGDQPGGTVITSGKGNT", "length": 1315, "header": "tr|F1N5F0-1|F1N5F0_BOVIN Isoform 1 of Granzyme M OS=Bos taurus OX=9913 GN=OVCH1 PE=4 SV=4 CANONICAL=F1N5F0-1" }, "locus": { "chromosome": "5", "start_pos": 80217298, "end_pos": 80123789, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000007060.8", "url": "https://www.ensembl.org/id/ENSBTAT00000007060.8" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000007060.7", "url": "https://www.ensembl.org/id/ENSBTAP00000007060.7" } ] } }, { "isoform_ac": "G3MX30-1", "url": "https://www.uniprot.org/uniprotkb/G3MX30/entry", "sequence": { "sequence": "MDRSPRMGAIRALPGAVSLLLLLLLAVHSPPSRGLKYGIHAVDLKSIETVLESRFFSRISSWRNSTVGGHPWQVSLKLGGHHFCGGSLIQDDLVVTAVHCLIGLNEKQIKSLTVTAGEYNLFQKDKEEQNIPVSKIIIHPEYNRLGYMSFNIALLYLKLKVKFGTTVQPICIPHRGDKFEEGIFCMASGWGKISETSEYSNILQEVEVPIMDDRRCGAMLRGMNLPPLGRDMLCASFPDGEKDACQRDSGGPLVCRRDDGVWVLAGITSWAAGCTRVWNPFRNKQRKASPGIFSKVFVLMDFITQTMTGECNFCGFFLPHPLQLKKMIMPISRIPYVATVNTLNYFFFSTDSLNKIGSTSFPKTNPRSSAKVIPYGVCGIPPFSPQWLSRRIAGGVEACPHCWPWQVGLRFLGNHQCGGAIINSIWILTAAHCVQSKNNPLFWTIVAGDHDITLKESTEQVRRAKHIVMHEDFDSLSYDSDIALIQLSSALEFNSVVRPVCLPHSLEPLFSSEICVVTGWGSANKDGGLASRLQQIQVPVLEREVCERTYYSAHPGGISEKMICAGFAASGEKDVGIQEGDSGGLLVCKHEKGPFVLYGIVSWGAGCDQPRKPGVFARVSVFLDWIQSKIKGPVLLQIKNESKILTRQQLPPPTPSRDSASGPGCYSEVELEEPRGFFSSPRYPLDYRGKLECSWVLRVSPSSMAKFTVEYLLLPWSHMCQDSALIIYEENHSERRMSGKLCGRRLYPMVFMSSGPLVRVTFHSSVQGAFGINYIVFRVQGPKGSKSTQSLQSSNQEHVATCEDVILTKPAGIIQFPRNFHRTIMSCHWRLLAPINHIIRLDIISFQKQPMPLACQGDLWVYEGFGSGKKLIVTLARFFTWPHLTESEMTREKGNGNVVWAG", "length": 902, "header": "tr|G3MX30-1|G3MX30_BOVIN Computationally mapped isoform of Ovochymase 1 OS=Bos taurus OX=9913 GN=OVCH1 PE=4 SV=3 CANONICAL=F1N5F0-1" }, "locus": { "chromosome": "5", "start_pos": 80184320, "end_pos": 80123789, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000063566.3", "url": "https://www.ensembl.org/id/ENSBTAT00000063566.3" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000054089.3", "url": "https://www.ensembl.org/id/ENSBTAP00000054089.3" } ] } } ], "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "other", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 612, "start_aa": "Thr", "end_pos": 612, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr612", "evidence": [ { "id": "", "database": "GlyGen", "url": "https://data.glygen.org/" } ], "filter_code": 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"field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": 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"table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ], "tool_support": { "graph_view": "yes" } }, { "uniprot_canonical_ac": "F1N5M9-1", "uniprot_ac": "F1N5M9", "uniprot_id": "F1N5M9_BOVIN", "mass": { "chemical_mass": 107872.0, "monoisotopic_mass": 107872.0 }, "refseq": {}, "gene_names": [ { "name": "MYCBPAP", "type": "recommended", "evidence": [ { "id": "F1N5M9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1N5M9" } ] } ], "protein_names": [ { "name": "MYCBP associated protein", "type": "synonym", "evidence": [ { "id": "F1N5M9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1N5M9/entry#names_and_taxonomy" } ] } ], "function": [], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Bos taurus", "taxid": 9913, "evidence": [ { "database": "UniProtKB", "id": "F1N5M9", "url": "https://www.uniprot.org/uniprotkb/F1N5M9" } ], "common_name": "Bovine", "glygen_name": "Bovine", "reference_species": "Bos taurus [9913]" } ], "gene": [ { "name": "MYCBPAP", "url": "https://www.uniprot.org/uniprotkb/F1N5M9", "locus": { "chromosome": "19", "start_pos": 36193740, "end_pos": 36216644, "strand": "+", "evidence": [ { "database": "Ensembl Gene", "id": "ENSBTAG00000014355", "url": "https://www.ensembl.org/id/ENSBTAG00000014355" } ] } } ], "crossref": [ { "id": "F1N5M9", "url": "https://alphafold.ebi.ac.uk/entry/F1N5M9", "database": "AlphaFoldDB", "categories": [] }, { "id": "ENSBTAG00000014355", "url": "https://bgee.org/?page=gene&gene_id=ENSBTAG00000014355", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "505551", "url": "https://www.ncbi.nlm.nih.gov/gene/505551", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR013783", "url": "https://www.ebi.ac.uk/interpro/entry/IPR013783", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR032707", "url": "https://www.ebi.ac.uk/interpro/entry/IPR032707", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "bta:505551", "url": "https://www.genome.jp/dbget-bin/www_bget?bta:505551", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "RESWEFR", "url": "https://omabrowser.org/oma/group/RESWEFR/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "A0A3Q1M7H3", "url": "https://www.orthodb.org/?gene=A0A3Q1M7H3", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "F1N5M9", "url": "https://www.orthodb.org/?gene=F1N5M9", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR48421", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR48421", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR48421:SF1", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR48421:SF1", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF14646", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF14646", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "A0A3Q1M7H3", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1M7H3", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A3Q1M7H3-1", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1M7H3-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "F1N5M9", "url": "https://www.uniprot.org/uniprotkb/F1N5M9", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "F1N5M9-1", "url": "https://www.uniprot.org/uniprotkb/F1N5M9-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MKKVASKQSPPKLFEKKRAKVPEQPTPPIQEEPEPVSNVLQGDDILALAIKKEDLRKQHLPRLIETEDKHVITQRFIIRKPKPKDHRKVSHLVAHPATPDAATKPLDYSGPGDIFHGSDQILPHHILGSLQDFKRIAVARGNTQLAELIHTPPCLMTLISTKEEPKQEAPKEEKAHPPWVPPLQHNFLKNWQRNIALRKKQQDALSERLKKPVSELLMHTGETYRQIQEERELLDRMLSTRSDGKGCKLTSGFWSRLEYVGDEMTGLVMTKTKTQHGLVEPITQIKKPWSIQAEMGLPAQKDAWYRYTWDRSLFLTCRRKELQSIMAELNFSQQDIDGLEVVGKGRPFSSVMVEDYSVFERSLESSSEDTVHLDLLANYPDVVPMPVLGPSLLFCGKPACWIRSSNSEDKRHVGIAVRLTFETLEGEKTSSELTVVNNGTVAIWYDWRRRSQWDSFQDLKRNRMQRFYFNNREGVILPGKTKNFTFFFKSLNAGIFRECWEFGTHPTLLGGALLQVNLHAVSLAQDIFRDERKLLESKLAAHEAVTVVENVLQELLRGILTPERTQSPVDASVTEEDLFHHRNPQLHYQHQVVQHLHSLWRQYMILPLKAEEARPGEEGHLSPRAQAAATPSAYSEETSMKIESSAHLKSPTLDPQLPRQESEAIKDSQDHVGSQKTGLGVRPSQRKSIMEEILVEGSPDLESIRSPWELDGLPLPEWNLCLEDFRKAVMALPEENQREDALIRLNKAALELCQEPRPLHPDFLYQMCLQLWRDLIDSLVSHSLWLRALLGLPEKETIYLDMPEEQDRKSPPVTEVKVTSGKVGKEDRKGASQEKKQFGIRDKEDKKGPRLSPGKEDRLNSKKHKTKDDKKPVKSLSRDGLSLDEPAPDSIIPSQEPIDPLVMEKYTHRLHTEVCGLLDALVTDLLALADDLHPQKNAEEPLRLCP", "length": 946, "header": "tr|F1N5M9-1|F1N5M9_BOVIN Isoform 1 of MYCBP associated protein OS=Bos taurus OX=9913 GN=MYCBPAP PE=4 SV=3 CANONICAL=F1N5M9-1" }, "isoforms": [ { "isoform_ac": "A0A3Q1M7H3-1", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1M7H3/entry", "sequence": { "sequence": "MKKVASKQSPPKLFEKKRAKVPEQPTPPIQEEPEPVSNVLQGDDILALAIKKEDLRKQHLPRLIETEDKHVITQRFIIRKPKPKDHRKVSHLVAHPATPDAATKPLDYSGPGDIFHGSDQILPHHILGSLQDFKRIAVARGNTQLAELIHTPPCLMTLISTKEEPKQEAPKEEKAHPPWVPPLQHNFLKNWQRNIALRKKQQDALSERLKKPVSELLMHTGETYRQIQEERELLDRMLSTRSDGKGCKLTSGFWSRLEYVGDEMTGLVMTKTKTQHGLVEPITQIKKPWSIQAEMGLPAQKDAWYRYTWDRSLFLTCRRKELQSIMAELNFSQQDIDGLEVVGKGRPFSSVMVEDYSVFERSLESSSEDTVHLDLLANYPDVVPMPVLGPSLLFCGKPACWIRSSNSEDKRHVGIAVRLTFETLEGEKTSSELTVVNNGTVAIWYDWRRRSQWDSFQDLKRNRMQRFYFNNREGVILPGKTKNFTFFFKSLNAGIFRECWEFGTHPTLLGGALLQVNLHAVSLAQDIFRDERKLLESKLAAHEAVTVVENVLQELLRGILTPERTQSPVDASVTEEDLFHHRNPQLHYQHQVVQHLHSLWRQYMILPLKAEEARPGEEGHLSPRAQAAATPSAYSEETSMKIESSAHLKSPTLDPQLPRQESEAIKDSQDHVGSQKTGLGVRPSQRKSIMEEILVEGSPDLESIRSPWELDGLPLPEWNLCLEDFRKAVMALPEENQREDALIRLNKAALELCQEPRPLHPDFLYQMCLQLWRDLIDSLVSHSLWLRALLGLPEKETIYLDMPEEQGGVPERRDDLPSYRKSPPVTEVKVTSGKVGKEDRKGASQEKKQFGIRDKEDKKGPRLSPGKEDRLNSKKHKTKDDKKPVKSLSRDGLSLDEPAPDSIIPSQEPIDPLVMEKYTHRLHTEVCGLLDALVTDLLALADDLHPQKNAEEPLRLCP", "length": 958, "header": "tr|A0A3Q1M7H3-1|A0A3Q1M7H3_BOVIN Computationally mapped isoform of MYCBP associated protein OS=Bos taurus OX=9913 GN=MYCBPAP PE=4 SV=1 CANONICAL=F1N5M9-1" }, "locus": { "chromosome": "19", "start_pos": 36216517, "end_pos": 36193825, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000079830.2", "url": "https://www.ensembl.org/id/ENSBTAT00000079830.2" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000064352.1", "url": "https://www.ensembl.org/id/ENSBTAP00000064352.1" } ] } }, { "isoform_ac": "F1N5M9-1", "url": "https://www.uniprot.org/uniprotkb/F1N5M9/entry", "sequence": { "sequence": "MKKVASKQSPPKLFEKKRAKVPEQPTPPIQEEPEPVSNVLQGDDILALAIKKEDLRKQHLPRLIETEDKHVITQRFIIRKPKPKDHRKVSHLVAHPATPDAATKPLDYSGPGDIFHGSDQILPHHILGSLQDFKRIAVARGNTQLAELIHTPPCLMTLISTKEEPKQEAPKEEKAHPPWVPPLQHNFLKNWQRNIALRKKQQDALSERLKKPVSELLMHTGETYRQIQEERELLDRMLSTRSDGKGCKLTSGFWSRLEYVGDEMTGLVMTKTKTQHGLVEPITQIKKPWSIQAEMGLPAQKDAWYRYTWDRSLFLTCRRKELQSIMAELNFSQQDIDGLEVVGKGRPFSSVMVEDYSVFERSLESSSEDTVHLDLLANYPDVVPMPVLGPSLLFCGKPACWIRSSNSEDKRHVGIAVRLTFETLEGEKTSSELTVVNNGTVAIWYDWRRRSQWDSFQDLKRNRMQRFYFNNREGVILPGKTKNFTFFFKSLNAGIFRECWEFGTHPTLLGGALLQVNLHAVSLAQDIFRDERKLLESKLAAHEAVTVVENVLQELLRGILTPERTQSPVDASVTEEDLFHHRNPQLHYQHQVVQHLHSLWRQYMILPLKAEEARPGEEGHLSPRAQAAATPSAYSEETSMKIESSAHLKSPTLDPQLPRQESEAIKDSQDHVGSQKTGLGVRPSQRKSIMEEILVEGSPDLESIRSPWELDGLPLPEWNLCLEDFRKAVMALPEENQREDALIRLNKAALELCQEPRPLHPDFLYQMCLQLWRDLIDSLVSHSLWLRALLGLPEKETIYLDMPEEQDRKSPPVTEVKVTSGKVGKEDRKGASQEKKQFGIRDKEDKKGPRLSPGKEDRLNSKKHKTKDDKKPVKSLSRDGLSLDEPAPDSIIPSQEPIDPLVMEKYTHRLHTEVCGLLDALVTDLLALADDLHPQKNAEEPLRLCP", "length": 946, "header": "tr|F1N5M9-1|F1N5M9_BOVIN Isoform 1 of MYCBP associated protein OS=Bos taurus OX=9913 GN=MYCBPAP PE=4 SV=3 CANONICAL=F1N5M9-1" }, "locus": { "chromosome": "19", "start_pos": 36216517, "end_pos": 36193825, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000019089.7", "url": "https://www.ensembl.org/id/ENSBTAT00000019089.7" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000019089.6", "url": "https://www.ensembl.org/id/ENSBTAP00000019089.6" } ] } } ], "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "other", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 26, "start_aa": "Thr", "end_pos": 26, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr26", "evidence": [ { "id": "", "database": "GlyGen", "url": "https://data.glygen.org/" } ], "filter_code": "000000000000000010000.00000000001000.0.01000" }, { "glytoucan_ac": "", "type": "O-linked", "subtype": "other", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 630, "start_aa": "Thr", "end_pos": 630, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr630", "evidence": [ { "id": "", "database": "GlyGen", "url": "https://data.glygen.org/" } ], "filter_code": "000000000000000010000.00000000001000.0.01000" } ], "phosphorylation": [], "glycation": [], "keywords": [ "glycoprotein", "glycoprotein_predicted" ], "publication": [], "pathway": [ { "id": "bta:505551", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?bta:505551", "resource": "KEGG Pathway" } ], "orthologs": [ { "uniprot_canonical_ac": "A0AB32TXP4-1", "protein_name": "MYCBP-associated protein isoform X1", "gene_name": "mycbpap", "tax_id": 7955, "organism": "Danio rerio", "sequence": { "sequence": "MSTVGKSTSKVSKRETKPRSPSEKKQFSPSSPSSLSSSSCVGEEDHSSALNTHDIQSLAITAQHLQKLRVPKPPPDSQKPRAMTRVLVRKTRPPDDVSRNVRVTVARPLPHDIAPPQTLEYTGPGGPRFDAQGMLLPHSILGNLEDFRSEMQLRGETELVQRIPDCEKQPPLVADTHNDSHQPEAHYYSGRQSHALQHWFRHMTDRRRQQDFIARFLQKPAGSLLMNRSSRFRSVQEQRTLIDRGLAAVYTEHGRRVGSEFWSVPQHYGDEMSGITATLTQTERGNPAELTRIAQPISTRLETGDVQGDAVNSVWQQSLYLQQRRRELKDMLRDFSPPDVDGLEVLGCGLPVPPSPLLDERQEKEEEEQKENQDPLAQFDDIIMDVELRPALSVCGEALCWTGSSSSHQGQEGVSVRLMFETVTGQSVNADLELKNEGSTVIYYSWEKLTPTHTQHFYFNNTTAVILPSSTKHICVTFKSASAGILTEVWRLNTHPVLMGGASVHVILRGVALDQDKSAEQRMALQVCVHACVCVCMSVDLHECVCVFVCACVNACVCVCIYACVFVCVCLQKELEQKACVCFCSRLILDLLTGVESPERPRSPDELYITDEERFHTHNPNLQFQRGPVEALQSLYAEVKRSEEQRWDLSIHTLTQVLLCVPESDESRETNLSRLNSLILELQRPAAIHTTAVTSHTISLQLWRELIDSLVCESVRLRHILGLQEHNAWSDTREEQHTLEQSEQQRAGVTRRRASVLELQEKSRAAEERGSMKKHMPEERKTDMVDTDETLQDTYTLMLHKQVYVLMERMVDSLCDLLDDAHNNPQKSL", "length": 829 }, "evidence": [ { "id": "F1N5M9", "url": "https://omabrowser.org/oma/group/F1N5M9/", "database": "OMA" } ], "glygen_name": "Zebrafish", "common_name": "Zebrafish" }, { "uniprot_canonical_ac": "Q5SUV2-1", "protein_name": "MYCBP-associated protein", "gene_name": "Mycbpap", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MMKKITERQSPLKLLEKKRAKAPEQPTPPIQEEPEPVSNVLQGDDILALAIKKEDLRKQHVPQFEETGEKPVVTQKFIIRKLKPKDSSKRVYHLVAHPATPDAATKPLDYSGPHDSFLSSGQILPHQILGSLQDFKRIAVARGNTQLAKLIHIQPCLMTLISAKEEPKPKPPKEEERPSPWAPPPQHNFLKNWRRHIALRKKQQEALSKHLKKPASELLMHTGESYRKIQEEREVIDRALPTQHDGKATSWFWSPLEYLGDEMTGLLMTKKKTQRGLVEPITHIRKPLSIQVETGLPAQKDAWYRYTWDRSLFLIYRRKELQSIMAELDFSQQDIDGLEVVGHGKPFSSVTVEEHLPPEKIQKSSSEDTVFLDSLTNLSDMVPMPILGPSLLFCGKPACWVRGSNPEDKKNIGIGVRLTFETLEGERTSSELTVVNNGTVAIWYNWRRRPHQDFFQDLKQNKTQRFYFNNREGVILPGETKHFTFFFKSLNAGIFRESWEFGTHPTLLGGAVLQVTLHAISLTQDIFMDERKLLETKLAAHEAITIAQSVLQDLLRGISTPERTPSPVDAYLTEEDLFNYRNPRLHYQHQVVQNLHQLWQQYRKAKATQKETPSLRTPVPLLLVEKASGSISPRNLVSEYSQLSPHQEMDTARKTRDFFLSLKSSIGKKSVARKSIMEELLVEEGPDRETTQRPWALKSISPPKWNLCLEDFRQAVMTFPEELQREDALIQLNKAAMELCQEQKPLQSDLLYQMCLQLWRDVIDSLVSQSLWLRNLLGLPEKETVYLDLPDEQGQKSPPVTESKVTSGKAGKEDRRGGAQEKKQLGTKDKDDKRGSKTPGKEDRPNSKKLKPKDDKKVVKSASRDRLLSEDPPPDSTAPSQEPIDPLVMEKYTQRLHAEVYALLDNLVTDVMVLADELSSTKNVEESLRFCS", "length": 932 }, "evidence": [ { "id": "F1N5M9", "url": "https://omabrowser.org/oma/group/F1N5M9/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q69CM7-1", "protein_name": "MYCBP-associated protein", "gene_name": "Mycbpap", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MKKANDRQSPPKLLEKKRAKAPEQPTPPIQEEPEPVSNVLQGDDILALAIKKEDLTKQHIPQFEETGEKPVVTQKFIIRKLKPKDSCKRVYHLVAHPANPDATTKPLDYSGPRDSFLSSDQILPHQILGSLQDFKRIAVARGNTQLAKLINIQPCLMTLISAKEEPKPKSPKEEKRPPWAPPLQHNFLKNWRRHITLRKKQQEVLSEHLKKPASELLMNSGEGYRKIQEEREAIDRALPTQHDRKAMNCFWSPLEYLGDEKSGLLMTKKKKQRGLVEPITHIRKPFSIQMETGLPVQKDAWYRYTWDRSLFLIYRRKGLQNIMAELDFSQQDIDGLEVVGHGKPFSSVTVEEPLPLEKSQKSSSEDTVFLDSLTNLSDMVPMPILGPSLLFCGKPACWIRGSNPEDKKNIGIGVRLTFETLEGEKTSSELTVVNNGTVAIWYDWRRRPQQDFFQDLKQNRTQRFYFNNREGVILPGETKHFTFFFKSRNAGIFMESWEFGTHPTLLGGAALQITLHAISLTQDIFMDERKLLESKLAAHEAVTIAQSVLQDLLRGVSTPERAPSPVDAYLTEEDLFHYRNPRLHYQHRVVQNLHQLWQQYTEAKASQEEALNLRTPTVPLLFVEKPPDHSRTLASEYPQLQPHQEMDTLKDPKNSLLPQKTGISTKSMQRKSIMEEILVEEGPDRENTRSPRVLENLPPPKWNLCLEDFRQAVMTFPEELQREDALIQLNKAAMELCQEQKPLQSDLLYQMCLQLWRDVIDSLVSQSLWLRSLLGLPEKETVYLDIPDEGQKSPPVTEVKVTSGKLGKEDRRGGAQEKKQLSARDKEEKKGSKTPSKEDRLNSKKQKAKDDKKVVKSTSRDRLLSEDPPADSSATSQEPIDPLVMEKYTQRLYSEVYGLLDNLVIDMMVLADELGSEKNVEEPLRFCT", "length": 928 }, "evidence": [ { "id": "F1N5M9", "url": "https://omabrowser.org/oma/group/F1N5M9/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "Q8TBZ2-1", "protein_name": "MYCBP-associated protein", "gene_name": "MYCBPAP", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MRAPARGTGCCGRSGGRWLAGAAQPRCLWAGGAGQRFMVPGGTMKSLKKDSRLRITPTRLLEASENVKEKKRAKGPEQPTPTIQEEPEPVSNVLQGDDILALAIKKEDLKEQHIPRLTEKEDKRVITQKFIIRKLKPMDPRRKVCHLVARPANPDEATKPLDYSGPGDSFDGSDQILPHHILGSLQDFKRIALARGNTQLAERIPTSPCLMTLISAEGESKQKAPKEEKRPPWAPPPQHNFLKNWQRNTALRKKQQEALSEHLKKPVSELLMHTGETYRRIQEERELIDCTLPTRRDRKSWENSGFWSRLEYLGDEMTGLVMTKTKTQRGLMEPITHIRKPHSIRVETGLPAQRDASYRYTWDRSLFLIYRRKELQRIMEELDFSQQDIDGLEVVGKGWPFSAVTVEDYTVFERSQGSSSEDTAYLGTLASSSDVSMPILGPSLLFCGKPACWIRGSNPQDKRQVGIAAHLTFETLEGEKTSSELTVVNNGTVAIWYDWRRQHQPDTFQDLKKNRMQRFYFDNREGVILPGEIKTFTFFFKSLTAGVFREFWEFRTHPTLLGGAILQVNLHAVSLTQDVFEDERKVLESKLTAHEAVTVVREVLQELLMGVLTPERTPSPVDAYLTEEDLFRHRNPPLHYEHQVVQSLHQLWRQYMTLPAKAEEARPGDKEHVSPIATEKASVNAELLPRFRSPISETQVPRPENEALRESGSQKARVGTKSPQRKSIMEEILVEESPDVDSTKSPWEPDGLPLLEWNLCLEDFRKAVMVLPDENHREDALMRLNKAALELCQKPRPLQSNLLHQMCLQLWRDVIDSLVGHSMWLRSVLGLPEKETIYLNVPEEQDQKSPPIMEVKVPVGKAGKEERKGAAQEKKQLGIKDKEDKKGAKLLGKEDRPNSKKHKAKDDKKVIKSASQDRFSLEDPTPDIILSSQEPIDPLVMGKYTQSLHSEVRGLLDTLVTDLMVLADELSPIKNVEEALRLCR", "length": 984 }, "evidence": [ { "id": "F1N5M9", "url": "https://omabrowser.org/oma/group/F1N5M9/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" } ], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 1, "go_terms": [ { "name": "cytoplasm", "id": "GO:0005737", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005737", "evidence": [ { "database": "UniProtKB", "id": "F1N5M9", "url": "https://www.uniprot.org/uniprotkb/F1N5M9" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 1, "go_terms": [ { "name": "spermatogenesis", "id": "GO:0007283", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007283", "evidence": [ { "database": "UniProtKB", "id": "F1N5M9", "url": "https://www.uniprot.org/uniprotkb/F1N5M9" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 330, "end_pos": 332, "annotation": "n_glycosylation_sequon" }, { "start_pos": 438, "end_pos": 440, "annotation": "n_glycosylation_sequon" }, { "start_pos": 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"mass": { "chemical_mass": 54282.0, "monoisotopic_mass": 54282.0 }, "refseq": { "ac": "XP_005223468", "name": "ectonucleotide pyrophosphatase/phosphodiesterase family member 5 isoform X1", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_005223468" }, "gene_names": [ { "name": "ENPP5", "type": "recommended", "evidence": [ { "id": "F1N5W4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1N5W4" } ] }, { "name": "ENPP5", "type": "synonym", "evidence": [ { "id": "XP_005223468", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_005223468" } ] } ], "protein_names": [ { "name": "Ectonucleotide pyrophosphatase/phosphodiesterase family member 5", "type": "synonym", "evidence": [ { "id": "F1N5W4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1N5W4/entry#names_and_taxonomy" } ] }, { "name": "ectonucleotide pyrophosphatase/phosphodiesterase family member 5 isoform X1", "type": "synonym", "evidence": [ { "id": "XP_005223468", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_005223468" } ] } ], "function": [], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Bos taurus", "taxid": 9913, "evidence": [ { "database": "UniProtKB", "id": "F1N5W4", "url": "https://www.uniprot.org/uniprotkb/F1N5W4" } ], "common_name": "Bovine", "glygen_name": "Bovine", "reference_species": "Bos taurus [9913]" } ], "gene": [ { "name": "ENPP5", "url": "https://www.uniprot.org/uniprotkb/F1N5W4", "locus": { "chromosome": "23", "start_pos": 19405834, "end_pos": 19415665, "strand": "+", "evidence": [ { "database": "Ensembl Gene", "id": "ENSBTAG00000015829", "url": "https://www.ensembl.org/id/ENSBTAG00000015829" } ] } } ], "crossref": [ { "id": "F1N5W4", "url": "https://alphafold.ebi.ac.uk/entry/F1N5W4", "database": "AlphaFoldDB", "categories": [] }, { "id": "ENSBTAG00000015829", "url": "https://bgee.org/?page=gene&gene_id=ENSBTAG00000015829", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "cd16018", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd16018", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "512304", "url": "https://www.ncbi.nlm.nih.gov/gene/512304", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR002591", "url": "https://www.ebi.ac.uk/interpro/entry/IPR002591", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR017850", "url": "https://www.ebi.ac.uk/interpro/entry/IPR017850", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "DEYVSRD", "url": "https://omabrowser.org/oma/group/DEYVSRD/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "F1N5W4", "url": "https://www.orthodb.org/?gene=F1N5W4", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR10151", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR10151", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR10151:SF125", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR10151:SF125", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF01663", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF01663", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "XP_005223468", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_005223468", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "F1N5W4", "url": "https://www.uniprot.org/uniprotkb/F1N5W4", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "F1N5W4-1", "url": "https://www.uniprot.org/uniprotkb/F1N5W4-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MTSKLLRVSFMLAALTLSVTFSLQSDQPKVLLVSFDGFRWDYLYRVPTPHFHYIMKYGVQVQQVTNIFITKTYPNHYTLVTGLFAENHGIVANDMYDPILNKSFSLDDMDIYDSEFWEEATPIWITNQRAGHTSGAAMWPGTDVKIHGSFPTHYMPYNDSVSFEDRVAKIIEWFTSKEPISLGLLYWEEPDDMGHQLGPDSPLMGPVISDIDHKLGYLIQMLKKAKLWNVLNLIITSDHGMTQCSQERIIELDQYLDREHYTLIDQSPVAAILPREGKFDEVYEALAQAHPNLTVYKKEEVPERWHYKHNSRIQPILAVADDGWHILRNKSDDFLLGNHGYDNALAEMHPIFLAHGPAFRKNFTKAAMNSTDLYPLLCHLLNITALPHNGSLSNVQDLLISPTPRASPNTQTPPLLHGSVKPRENEQDESYAYFIGVSLGSVIVIVFLIVLIKHLIRSQIPALPDFQAEISQPLLQA", "length": 477, "header": "tr|F1N5W4-1|F1N5W4_BOVIN Isoform 1 of Ectonucleotide pyrophosphatase/phosphodiesterase family member 5 OS=Bos taurus OX=9913 GN=ENPP5 PE=3 SV=3 CANONICAL=F1N5W4-1" }, "isoforms": [ { "isoform_ac": "F1N5W4-1", "url": "https://www.uniprot.org/uniprotkb/F1N5W4/entry", "sequence": { "sequence": "MTSKLLRVSFMLAALTLSVTFSLQSDQPKVLLVSFDGFRWDYLYRVPTPHFHYIMKYGVQVQQVTNIFITKTYPNHYTLVTGLFAENHGIVANDMYDPILNKSFSLDDMDIYDSEFWEEATPIWITNQRAGHTSGAAMWPGTDVKIHGSFPTHYMPYNDSVSFEDRVAKIIEWFTSKEPISLGLLYWEEPDDMGHQLGPDSPLMGPVISDIDHKLGYLIQMLKKAKLWNVLNLIITSDHGMTQCSQERIIELDQYLDREHYTLIDQSPVAAILPREGKFDEVYEALAQAHPNLTVYKKEEVPERWHYKHNSRIQPILAVADDGWHILRNKSDDFLLGNHGYDNALAEMHPIFLAHGPAFRKNFTKAAMNSTDLYPLLCHLLNITALPHNGSLSNVQDLLISPTPRASPNTQTPPLLHGSVKPRENEQDESYAYFIGVSLGSVIVIVFLIVLIKHLIRSQIPALPDFQAEISQPLLQA", "length": 477, "header": "tr|F1N5W4-1|F1N5W4_BOVIN Isoform 1 of Ectonucleotide pyrophosphatase/phosphodiesterase family member 5 OS=Bos taurus OX=9913 GN=ENPP5 PE=3 SV=3 CANONICAL=F1N5W4-1" }, "locus": { "chromosome": "23", "start_pos": 19412664, "end_pos": 19406126, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000057413.4", "url": "https://www.ensembl.org/id/ENSBTAT00000057413.4" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000052332.3", "url": "https://www.ensembl.org/id/ENSBTAP00000052332.3" } ] } } ], "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "other", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 403, "start_aa": "Thr", "end_pos": 403, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr403", "evidence": [ { "id": "", "database": "GlyGen", "url": "https://data.glygen.org/" } ], "filter_code": "000000000000000010000.00000000001000.0.01000" } ], "phosphorylation": [], "glycation": [], "keywords": [ "glycoprotein", "glycoprotein_predicted" ], "publication": [], "pathway": [], "orthologs": [ { "uniprot_canonical_ac": "A0A287ALD4-1", "protein_name": "Ectonucleotide pyrophosphatase/phosphodiesterase family member 5", "gene_name": "ENPP5", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MTSKFLWVCFLLAALTLAKTYSLQPDQQKVLLVSFDGFRWDYLYRVPTPHFHYVMKHGVHVKQVTNIFITKTYPNHYTLVTGLFAENHGIVANDMFDPILNKSFSLDNMDIYDSEFWEEATPIWITNQRAGHTSGAAMWPGTDVKIHESFPTHYLPYNESVSFEERVAKIIEWFTSKEPINLGLLYWEEPDDMGHHLGPDSPLMGPVISDTDHKLGYLIQMLKKAKLWNVLNLIITSDHGMTQCSEERVIELDQYLDRDHYTLIDQSPVAAILPKEGKFDEVYEALAHAHPNLTVYKKEEIPERWHYRYNSRIQPIIAVADNGWYVLRNKSDDFLLGNHGYDNALAEMHPIFLAHGPAFRKNFTREAMNSTDLYPLLCHLLNITGMPHNGSLRNVQDLLSSTAPRASPYTQSPPFLRGGVKPRENEQEESYAYFLGVSLGAIIVIVFLITFTKHLIRSQIPALPDFQSEISQPLLQA", "length": 477 }, "evidence": [ { "id": "F1N5W4", "url": "https://omabrowser.org/oma/group/F1N5W4/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "A0A2R8QE68-1", "protein_name": "3.6.1.29", "gene_name": "enpp5", "tax_id": 7955, "organism": "Danio rerio", "sequence": { "sequence": "MPDFSVIRSCFLSCLLALLQTSGSQQEEQNQLLLVSFDGFRWDYINRVPTPNFHALMDEGVLVEKVENTYITKTYPNHYTLVTGLHAESHGVVANEMYDPIHNRSFSIEGPEVYDAWWWEEAEPLWVTNQKAGRKSGAAMWPGSDVAIGGTFPTHYLRYNASMLFETRVQKLIDWFSGPEAINFGVLYWEEPDESGHNLGPESPLMDVVLADIDEKLGFLREKLKSAGLYDKVNLIVTSDHGMTQLSHDKIIELDTYVSRDLYTWIDKSPVVGILPKEGKLEEVYGLLKNANPNMVVYKKEEIPDHYHYRHNARIMPLIIEVKEGWTVMQNRNGSFMLGNHGYNNSLPNMHPVFVARGPAFRRDYTKTSMRSVDLYPLMCSILALKPLPNNGSLSSVQDLLVETSTPKPTVTPVPRGPMVPPVPREPSYAWAVGCILGAGLVIGFLFIFVKQVTQRQLPPLYLSNSEITQPLL", "length": 473 }, "evidence": [ { "id": "F1N5W4", "url": "https://omabrowser.org/oma/group/F1N5W4/", "database": "OMA" } ], "glygen_name": "Zebrafish", "common_name": "Zebrafish" }, { "uniprot_canonical_ac": "G3I3Q9-1", "protein_name": "Ectonucleotide pyrophosphatase/phosphodiesterase family member 5 isoform X1", "gene_name": "Enpp5", "tax_id": 10029, "organism": "Cricetulus griseus", "sequence": { "sequence": "MIPKFLMVSCTLAALTHSTTFSLQPEHQKVLVVSFDGFRWDYIYKVPTPYFHYIMKYGVHVKQVTNVFITKTYPNHYTLVTGLFAENHGIVANDMFDPILNKSFSLDHMDIYDSEFWEEATPIWITNQRAGHASGAAMWPGTDVKIHESFPTYYLPYNESVSFEDRVAKIIEWFTAKDPINLGLLYWEEPDDTGHDVGPDSPLMGPVISDIDHKLGYLIKMLKKAKLWNNVNLIITSDHGMTQCSKQRVIELDRYLDRDHYTLIDHSPVAAILPKEGKFDEVYDVLARAHPNLTVYKKEEIPERWHYKHNDRVQPILAVADEGWYILQNKSDDFLLGNHGYDNALAEMHPIFLAHGPAFRKNFTKEAMNSTDLYPLLCHLLNITALPHNGSIRNVQDLLSSATLKAIPYTQSTPHLLGSDKPVEHEQEESYPYYIGISLGSIIAIVFSVVLIKHLIHSQVPTLQYMQVEVAQPLLQA", "length": 477 }, "evidence": [ { "id": "F1N5W4", "url": "https://omabrowser.org/oma/group/F1N5W4/", "database": "OMA" } ], "glygen_name": "Hamster", "common_name": "Chinese hamster" }, { "uniprot_canonical_ac": "P84039-1", "protein_name": "Ectonucleotide pyrophosphatase/phosphodiesterase family member 5", "gene_name": "Enpp5", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MIPEFLVVSCTLAALCHSVPLSLQTEQQKVLVVSFDGFRWDYLYKVPTPHFHYVMKNGVHVKQVTNVFITKTYPNHYTLVTGLFAENHGIVANDMFDPVLNKSFSLEHMNIYDSKFWEEATPLWITNQRAGHASGAAMWPGTDVKIHESYPTHYLPYNESVSFEDRVAKIIEWFTAKDPINLGFLYWEEPDDTGHDVGPDSPLMGPVISDIDHKLGYLIKMLKKAKLWNNINLIVTSDHGMTQCSKERVIELDQYLDKEHYTLIDHSPVAAILPKEGKFNEVYDALANAHPNLTVYKKEEIPERWHYKHSDRVQPIVAVADEGWYILQNKSDEFLLGNHGYDNALAEMHPIFLAHGPAFRKNFTKEAMNSTDLYSLVCHLLNVTALPHNGSFRNVQDLLSSAAPKAIPYTQSTTLPLGSAKPGEYEQEESYPYYIGISLGSLIAIVFFVVLIKHLIRSQMHTLQYMQVEVAQPLLQA", "length": 477 }, "evidence": [ { "id": "F1N5W4", "url": "https://omabrowser.org/oma/group/F1N5W4/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "Q54MJ8-1", "protein_name": "Type I phosphodiesterase/nucleotide pyrophosphatase family protein", "gene_name": "", "tax_id": 44689, "organism": "Dictyostelium discoideum", "sequence": { "sequence": "MSNNNNNNNNNNNNNNNNNNNNNNPNNNNNININVDHSYDDVDFNNKDPLFFSSGNEYMYRADEDDLEYDDDEDTNDGGGGGGGGSGNGGKKKKKKKEFLIDGFDENSESLVRSKDSDTIGYRIRNRLEYLEKGTKIIIFVGLITLTVVLCSIGLYFYAKDHKSPLVNYIHPTPVIVISLDGFRWDYLNRGLTPNIKKLIEDGSYHANYTIPQFPSKTFPNHYSIATGLYPENHGIISNHMYDPILNKTFDINKASVTDSEWYWGEPIWVTSEIHGIKSACYFWPGCGVMIKDRFPTYNKLPFTMDISAKTVFDTVFKWAQLDASEKPYLSMAYVHEVDDAGHIYGPDSQQVNDAIAYLDTQIGSLIDQLKSTNQYNSTNLIILSDHGMASVPKNQSIYLDDLTNDPSFSTKCYIRDMSPILSIFPIVGGLSIDEIYKSLTANSDINIKIYKKEDLPKELFFSLNENKRIAPIIGIVNLGYTLVQSKSTPTTSWELGNHGFNPSFEQMKSIFIGHGPNIKSLPIDDQNLPPFKNIEIYNFISTLLNIKSPSPNNGTTLLTDKLYLK", "length": 566 }, "evidence": [ { "id": "F1N5W4", "url": "https://omabrowser.org/oma/group/F1N5W4/", "database": "OMA" } ], "glygen_name": "Cellular slime mold", "common_name": "Social amoeba" }, { "uniprot_canonical_ac": "Q9EQG7-1", "protein_name": "Ectonucleotide pyrophosphatase/phosphodiesterase family member 5", "gene_name": "Enpp5", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MIPEFLLASCTLATLCHSAPFSLQPEEQKVLVVSFDGFRWDYLYKVPTPHFHYIMKNGVHVNQVTNVFITKTYPNHYTLVTGLFAENHGIVANDMFDPILNKSFSLEHMDIYDSKFWEEATPIWITNQRAGHASGAAMWPGADVKIHDSFPTYYLPYNESVSFEDRVAKIIEWFTAKDPINLGFLYWEEPDDTGHDVGPDSPLMGSVISDVDHKLGYLIKMLKRAKLWNNVNLIVTSDHGMTQCSKQRVIELDRYLDKEHYTLIDHSPVAAILPKEGKFDEVYDALAGAHPNLTVYKKEEIPERWHYKHNDRVQPIVAVADEGWYILQNKSDDFLLGNHGYDNALAEMHPIFLAHGPAFRKNFTKEAMNSTDLYSLLCHLLNLTALPHNGSFWNVQDLLSSATPKPIPYTQSTTLLLGSDKPGEDEQEESYPYYIGVSLGSIIAMVFFVVLIKHLIRSQVHTLQYRQVEVAQPLLQA", "length": 477 }, "evidence": [ { "id": "F1N5W4", "url": "https://omabrowser.org/oma/group/F1N5W4/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q9SU83-1", "protein_name": "nucleotide diphosphatase", "gene_name": "", "tax_id": 3702, "organism": "Arabidopsis thaliana", "sequence": { "sequence": "MISGDTLSAKKPKSVPQEEDQDPPSQSIALLDNHTDSSGSDSSTRSISSCFIFTSLLLVTCIALSAASAFAFLFFSSQKPVLSLNQISKSPAFDRSVARPLKKLDKPVVLLISSDGFRFGYQFKTKLPSIHRLIANGTEAETGLIPVFPTLTFPNHYSIVTGLYPAYHGIINNHFVDPETGNVFTMASHEPEWWLGEPLWETVVNQGLKAATYFWPGSEVHKGSWNCPQGLCQNYNGSVPFDDRVDTILSYFDLPSNEIPSFMTLYFEDPDHQGHQVGPDDPQITEAVVNIDRLIGRLIDGLEKRGIFEDVTMIMVGDHGMVGTCDKKLVVLDDLAPWIKIPSSWVQYYTPLLAIQPPSGHDAADIVAKINEGLSSGKVENGKYLKVYLKEDLPSRLHYVDSDRIPPIIGLVDEGFKVEQKKSKAKECGGAHGYDNAFFSMRTIFIGHGPMFSKGRKVPSFENVQIYNVISSILGLKAAPNNGSDEFSSSILLPRV", "length": 496 }, "evidence": [ { "id": "F1N5W4", "url": "https://omabrowser.org/oma/group/F1N5W4/", "database": "OMA" } ], "glygen_name": "Arabidopsis", "common_name": "Mouse-ear cress" }, { "uniprot_canonical_ac": "Q9UJA9-1", "protein_name": "Ectonucleotide pyrophosphatase/phosphodiesterase family member 5", "gene_name": "ENPP5", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MTSKFLLVSFILAALSLSTTFSLQPDQQKVLLVSFDGFRWDYLYKVPTPHFHYIMKYGVHVKQVTNVFITKTYPNHYTLVTGLFAENHGIVANDMFDPIRNKSFSLDHMNIYDSKFWEEATPIWITNQRAGHTSGAAMWPGTDVKIHKRFPTHYMPYNESVSFEDRVAKIIEWFTSKEPINLGLLYWEDPDDMGHHLGPDSPLMGPVISDIDKKLGYLIQMLKKAKLWNTLNLIITSDHGMTQCSEERLIELDQYLDKDHYTLIDQSPVAAILPKEGKFDEVYEALTHAHPNLTVYKKEDVPERWHYKYNSRIQPIIAVADEGWHILQNKSDDFLLGNHGYDNALADMHPIFLAHGPAFRKNFSKEAMNSTDLYPLLCHLLNITAMPHNGSFWNVQDLLNSAMPRVVPYTQSTILLPGSVKPAEYDQEGSYPYFIGVSLGSIIVIVFFVIFIKHLIHSQIPALQDMHAEIAQPLLQA", "length": 477 }, "evidence": [ { "id": "F1N5W4", "url": "https://omabrowser.org/oma/group/F1N5W4/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" } ], "go_annotation": { "categories": [ { "name": "Molecular Function", "total": 3, "go_terms": [ { "name": "NAD+ diphosphatase activity", "id": "GO:0000210", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000210", "evidence": [ { "database": "UniProtKB", "id": "F1N5W4", "url": "https://www.uniprot.org/uniprotkb/F1N5W4" } ], "pmid": "" }, { "name": "zinc ion binding", "id": "GO:0008270", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008270", "evidence": [ { "database": "UniProtKB", "id": "F1N5W4", "url": "https://www.uniprot.org/uniprotkb/F1N5W4" } ], "pmid": "" }, { "name": "hydrolase activity", "id": "GO:0016787", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016787", "evidence": [ { "database": "UniProtKB", "id": "F1N5W4", "url": "https://www.uniprot.org/uniprotkb/F1N5W4" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 1, "go_terms": [ { "name": "membrane", "id": "GO:0016020", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016020", "evidence": [ { "database": "UniProtKB", "id": "F1N5W4", "url": "https://www.uniprot.org/uniprotkb/F1N5W4" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 101, "end_pos": 103, "annotation": "n_glycosylation_sequon" }, { "start_pos": 158, "end_pos": 160, "annotation": "n_glycosylation_sequon" }, { "start_pos": 292, "end_pos": 294, 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"url": "https://www.uniprot.org/uniprotkb/F1N6D7/entry", "sequence": { "sequence": "KFLIRVPLFPRPPLQVRTASETDNLTSKPLTSSFSSSSPTVWEKQTSQEKPETASTSHPDSSSSESTISHSPSNSGTTSTTQPTSSQPEPDTHPSSGSPSSEHTVTSPSLGSVSLATMPWSPTHPKPSTGPPSVSLATTDRTFETSGYAPGDSGVPRLHRNPGVVVAVCLLVSALLIGGAIMAVRRCHNGVSEFQKLDEGLVSRRSSSAHHTLP", "length": 214, "header": "tr|F1N6D7-1|F1N6D7_BOVIN Isoform 1 of Colon, intestine and stomach enriched 1 OS=Bos taurus OX=9913 GN=CIST1 PE=4 SV=2 CANONICAL=F1N6D7-1" }, "locus": { "chromosome": "7", "start_pos": 4984401, "end_pos": 4979677, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000048089.5", "url": "https://www.ensembl.org/id/ENSBTAT00000048089.5" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000045189.3", "url": "https://www.ensembl.org/id/ENSBTAP00000045189.3" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [], "orthologs": [], "go_annotation": {}, "pro_annotation": [], 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"RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001039718" } ] } ], "function": [], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Bos taurus", "taxid": 9913, "evidence": [ { "database": "UniProtKB", "id": "F1N6I1", "url": "https://www.uniprot.org/uniprotkb/F1N6I1" } ], "common_name": "Bovine", "glygen_name": "Bovine", "reference_species": "Bos taurus [9913]" } ], "gene": [ { "name": "C5H22orf23", "url": "https://www.uniprot.org/uniprotkb/F1N6I1", "locus": { "chromosome": "5", "start_pos": 109738012, "end_pos": 109745876, "strand": "+", "evidence": [ { "database": "Ensembl Gene", "id": "ENSBTAG00000019563", "url": "https://www.ensembl.org/id/ENSBTAG00000019563" } ] } } ], "crossref": [ { "id": "F1N6I1", "url": "https://alphafold.ebi.ac.uk/entry/F1N6I1", "database": "AlphaFoldDB", "categories": [] }, { "id": "ENSBTAG00000019563", "url": "https://bgee.org/?page=gene&gene_id=ENSBTAG00000019563", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "520712", "url": "https://www.ncbi.nlm.nih.gov/gene/520712", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR007914", "url": "https://www.ebi.ac.uk/interpro/entry/IPR007914", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "bta:520712", "url": "https://www.genome.jp/dbget-bin/www_bget?bta:520712", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "MMAYGKD", "url": "https://omabrowser.org/oma/group/MMAYGKD/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "F1N6I1", "url": "https://www.orthodb.org/?gene=F1N6I1", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR28348", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR28348", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR28348:SF1", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR28348:SF1", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF05250", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF05250", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "NP_001039718", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001039718", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0AAA9TXJ9", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TXJ9", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0AAA9TXJ9-1", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TXJ9-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "F1N6I1", "url": "https://www.uniprot.org/uniprotkb/F1N6I1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "F1N6I1-1", "url": "https://www.uniprot.org/uniprotkb/F1N6I1-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MASQERVETVTKGTGFWRCPKPTTYTPGTCELLRVMMKESKLTNFQQRHITDTMKRGDTLPLQCNPTSSQRVLPSKQPSSAIYLPPILAARSHLRPAWRCQANGAYSREQFKPQATRDLEMEKRRLQNIFATGKEPEERKRKPHPLRQEDPAPKLDRFEELVKEIQERKEFLADMEALGQGRQYRGIILTEISQKLQEMEDIDHKRSEELRKALATT", "length": 217, "header": "tr|F1N6I1-1|F1N6I1_BOVIN Isoform 1 of Chromosome 5 C22orf23 homolog OS=Bos taurus OX=9913 GN=C5H22orf23 PE=4 SV=1 CANONICAL=F1N6I1-1" }, "isoforms": [ { "isoform_ac": "A0AAA9TXJ9-1", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TXJ9/entry", "sequence": { "sequence": "MASQERVETVTKGTGFWRCPKPTTYTPGTCELLRGGDTLPLQCNPTSSQRVLPSKQPSSAIYLPPILAARSHLRPAWRCQANGAYSREQFKPQATRDLEMEKRRLQNIFATGKEPEERKRKPHPLRQEDPAPKLDRFEELVKEIQERKEFLADMEALGQGRQYRGIILTEISQKLQEMEDIDHKRSEELRKALATT", "length": 196, "header": "tr|A0AAA9TXJ9-1|A0AAA9TXJ9_BOVIN Computationally mapped isoform of Chromosome 5 C22orf23 homolog OS=Bos taurus OX=9913 GN=C5H22orf23 PE=4 SV=1 CANONICAL=F1N6I1-1" }, "locus": { "chromosome": "5", "start_pos": 109745373, "end_pos": 109738641, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000089158.1", "url": "https://www.ensembl.org/id/ENSBTAT00000089158.1" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000103381.1", "url": "https://www.ensembl.org/id/ENSBTAP00000103381.1" } ] } }, { "isoform_ac": "F1N6I1-1", "url": "https://www.uniprot.org/uniprotkb/F1N6I1/entry", "sequence": { "sequence": "MASQERVETVTKGTGFWRCPKPTTYTPGTCELLRVMMKESKLTNFQQRHITDTMKRGDTLPLQCNPTSSQRVLPSKQPSSAIYLPPILAARSHLRPAWRCQANGAYSREQFKPQATRDLEMEKRRLQNIFATGKEPEERKRKPHPLRQEDPAPKLDRFEELVKEIQERKEFLADMEALGQGRQYRGIILTEISQKLQEMEDIDHKRSEELRKALATT", "length": 217, "header": "tr|F1N6I1-1|F1N6I1_BOVIN Isoform 1 of Chromosome 5 C22orf23 homolog OS=Bos taurus OX=9913 GN=C5H22orf23 PE=4 SV=1 CANONICAL=F1N6I1-1" }, "locus": { "chromosome": "5", "start_pos": 109745373, "end_pos": 109738641, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000026065.6", "url": "https://www.ensembl.org/id/ENSBTAT00000026065.6" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000026065.5", "url": "https://www.ensembl.org/id/ENSBTAP00000026065.5" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [ { "id": "bta:520712", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?bta:520712", "resource": "KEGG Pathway" } ], "orthologs": [ { "uniprot_canonical_ac": "A0A3L7I2P0-1", "protein_name": "UPF0193 protein EVG1 isoform X2", "gene_name": "C2H22orf23", "tax_id": 10029, "organism": "Cricetulus griseus", "sequence": { "sequence": "MASQERVDAVSNGTGFQRCGKQLAYTPGTCELLRVMMKESRLTNFQQRHIMDTVKRGAPLPLQCDPTSSHRGSPSKKPATATYLPPILATHSHLRPASMCQANGAYSREQFKPQATRDLEKEKRRLQNIFANGKDIEERKRAPHGLQEDPAPELDRFEELVKEIQDRKEFLAAMEALGQGKQYRGMILAEISQKLQEMEEIDRSRSEKLRKALATT", "length": 216 }, "evidence": [ { "id": "F1N6I1", "url": "https://omabrowser.org/oma/group/F1N6I1/", "database": "OMA" } ], "glygen_name": "Hamster", "common_name": "Chinese hamster" }, { "uniprot_canonical_ac": "A0A5G2QM26-1", "protein_name": "Chromosome 5 C22orf23 homolog", "gene_name": "C5H22orf23", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MASQERVETVTKGTGFWRCPKPAAYTPRTCELLRAMMKESKLTNFQQRHIMDTMKRGDALPLHCSPTSSQRVLPARQPASAIYLPPILAARSHLRPASLCQANGAYSREQFRPQATRDLEKEKRRLQNIFATGKEPEERKRKPPPVQQEAPAPELDRFEELVKEIQERKAFLADMEALGQGRRYRGVILTEISQKLQEMEDLDRKRSEELRKALATP", "length": 217 }, "evidence": [ { "id": "F1N6I1", "url": "https://omabrowser.org/oma/group/F1N6I1/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "E7F0P7-1", "protein_name": "UPF0193 protein EVG1", "gene_name": "si:dkey-43k4.3", "tax_id": 7955, "organism": "Danio rerio", "sequence": { "sequence": "MMASGSKYKESGIPQYRTDTRQLIKLMMQESRLTDFQQRQINNKLKNGGALPITFYSSPLEPNTPSETRVTRVGTLVGQQQKRSAERCRAGDNYKREQFLPSAARDLEKEKRKLQNLLSTGQKDAGPTHSQRESTERREQPVDRFQEVLDEIEDRRQFLEEMMSLGKGHQYQQLINTEISQKICELEEIDKKRSEELRTPQLTGKEEQ", "length": 208 }, "evidence": [ { "id": "F1N6I1", "url": "https://omabrowser.org/oma/group/F1N6I1/", "database": "OMA" } ], "glygen_name": "Zebrafish", "common_name": "Zebrafish" }, { "uniprot_canonical_ac": "F7FLU1-1", "protein_name": "Similar to human chromosome 22 open reading frame 23", "gene_name": "C7h22orf23", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MNPPMASQERVDAVANGTGFHRCRKQAAYTPGTCELLRVMMKESKLTNFQQRHIMDTMKRGAPLPLQCNPTSSQRGSPSKKSAAAIYLPPILATHTHLRPASLCQANGAYSREQFKPQATRDLEKEKRRLQNIFATGKDMEERKKVPHVQQEDPAPELDRFDELVKEIQDRKEFLAAMEALGQGKQYRGIILAEISQKLREMEDIDRRRSKELRKALTTT", "length": 220 }, "evidence": [ { "id": "F1N6I1", "url": "https://omabrowser.org/oma/group/F1N6I1/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "Q9BZE7-1", "protein_name": "UPF0193 protein EVG1", "gene_name": "C22orf23", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MASQKQMEVVTKGTGFRRRPKTITYTPGTCELLRVMMKESKLTNIQQRHIMDIMKRGDALPLQCSPTSSQRVLPSKQIASPIYLPPILAARPHLRPANMCQANGAYSREQFKPQATRDLEKEKQRLQNIFATGKDMEERKRKAPPARQKAPAPELDRFEELVKEIQERKEFLADMEALGQGKQYRGIILAEISQKLREMEDIDHRRSEELRKGLATT", "length": 217 }, "evidence": [ { "id": "F1N6I1", "url": "https://omabrowser.org/oma/group/F1N6I1/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "Q9D9S1-1", "protein_name": "UPF0193 protein EVG1 homolog", "gene_name": "", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MASQERVDSVTKGTGFRRCRKQAGYTPGTCELLRVMMKESKLTNFQQRHIMDTMKRGAPLPLQCNPTSSLRGSPSKKAASAIYLPPILATHSHLRPASLCQANGAYSREQFKPQATRDLEKEKRRLQNIFATGKDKEERKKVPHVRQEDPAPELDRFDELVKEIQDRKEFLAAMEALGQGRQYRSIILAEISQKLREMEDIDRRRSKELRKALATT", "length": 216 }, "evidence": [ { "id": "F1N6I1", "url": "https://omabrowser.org/oma/group/F1N6I1/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q9VSS7-1", 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"https://omabrowser.org/oma/group/QCYCFGS/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "F1N6L2", "url": "https://www.orthodb.org/?gene=F1N6L2", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR24364", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR24364", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR24364:SF16", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR24364:SF16", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF01463", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF01463", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF13855", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF13855", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "XP_015330279", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_015330279", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "F1N6L2", "url": "https://www.uniprot.org/uniprotkb/F1N6L2", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "F1N6L2-1", "url": "https://www.uniprot.org/uniprotkb/F1N6L2-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MAPRAGQPEHRGPLLPGLLLVAAALSRPAAPCPFQCYCFGGPKLMLRCASGAELRQPPRDVPPDARNLTIVGANLTVLRAAAFAGGDADGEEAAEGGVRLPHLTALRLTHNNIEVVEDGAFDGLPSLTALDLSHNPLRTLGGGAFRGLPALRSLQLNHALARGGPALLAALDAALAPLDELRLLGLAGNALSRLPPAALRRPRLEQLDVHLNALAGLDPDELRALERDGGLPAPRLLLADNPLRCGCAARPLLAWLRNSTERVPDARRLRCAAPRALHNRPFLDLEEAQLRCADSDADSRGDEVELAGPELEASYVFFGLVLALIGLIFLMVLYLNRRGIQRWMRNLREACRDQMEGYHYRYEQDADPRRAPARAAPAGSRATSPGSGL", "length": 389, "header": "tr|F1N6L2-1|F1N6L2_BOVIN Isoform 1 of Trophoblast glycoprotein like OS=Bos taurus OX=9913 GN=TPBGL PE=4 SV=3 CANONICAL=F1N6L2-1" }, "isoforms": [ { "isoform_ac": "F1N6L2-1", "url": "https://www.uniprot.org/uniprotkb/F1N6L2/entry", "sequence": { "sequence": "MAPRAGQPEHRGPLLPGLLLVAAALSRPAAPCPFQCYCFGGPKLMLRCASGAELRQPPRDVPPDARNLTIVGANLTVLRAAAFAGGDADGEEAAEGGVRLPHLTALRLTHNNIEVVEDGAFDGLPSLTALDLSHNPLRTLGGGAFRGLPALRSLQLNHALARGGPALLAALDAALAPLDELRLLGLAGNALSRLPPAALRRPRLEQLDVHLNALAGLDPDELRALERDGGLPAPRLLLADNPLRCGCAARPLLAWLRNSTERVPDARRLRCAAPRALHNRPFLDLEEAQLRCADSDADSRGDEVELAGPELEASYVFFGLVLALIGLIFLMVLYLNRRGIQRWMRNLREACRDQMEGYHYRYEQDADPRRAPARAAPAGSRATSPGSGL", "length": 389, "header": "tr|F1N6L2-1|F1N6L2_BOVIN Isoform 1 of Trophoblast glycoprotein like OS=Bos taurus OX=9913 GN=TPBGL PE=4 SV=3 CANONICAL=F1N6L2-1" }, "locus": { "chromosome": "15", "start_pos": 54464403, "end_pos": 54463237, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000026139.7", "url": "https://www.ensembl.org/id/ENSBTAT00000026139.7" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000026139.6", "url": "https://www.ensembl.org/id/ENSBTAP00000026139.6" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [ { "id": "bta:786625", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?bta:786625", "resource": "KEGG Pathway" } ], "orthologs": [ { "uniprot_canonical_ac": "A0A8V0XKW5-1", "protein_name": "Trophoblast glycoprotein like", "gene_name": "TPBGL", "tax_id": 9031, "organism": "Gallus gallus", "sequence": { "sequence": "MVRRTRRAAGLGLPCLGLPWLGLALLPWAVPPAAAPPGGCPSACYCVATPELVQCRYESLDEPPRELPTSVHNLSISGSNLSVLHRAAFAPLPLPDLRLLRLRHDNIQTIEDMALQGLPALRTLDLSHNPLRSVAAGAFSGVPLLRTLQLNQALLAAPLEEQLALAMRNLSLHRLELAGNGLRALPASLLPTGLEELDLRNNSLQRLTSTELLSLEAPGLRGLRVSLGANPLQCDCALRPLLAWLRSSAARVSDARSLQCSKPPSLRGTAVLRLRPEGLGCTADEGGEAGQLETASYVFFGIVLALIGIVFLMVLYLNRRGIKRWLHNLREACRDQMEGYHYRYEQDADPRRASAVGTPGL", "length": 361 }, "evidence": [ { "id": "F1N6L2", "url": "https://omabrowser.org/oma/group/F1N6L2/", "database": "OMA" } ], "glygen_name": "Chicken", "common_name": "Chicken" }, { "uniprot_canonical_ac": "P0DKB5-1", "protein_name": "Trophoblast glycoprotein-like", "gene_name": "TPBGL", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MAPRAGQPGLQGLLLVAAALSQPAAPCPFQCYCFGGPKLLLRCASGAELRQPPRDVPPDARNLTIVGANLTVLRAAAFAGGDGDGDQAAGVRLPLLSALRLTHNHIEVVEDGAFDGLPSLAALDLSHNPLRALGGGAFRGLPALRSLQLNHALVRGGPALLAALDAALAPLAELRLLGLAGNALSRLPPAALRLARLEQLDVRLNALAGLDPDELRALERDGGLPGPRLLLADNPLRCGCAARPLLAWLRNATERVPDSRRLRCAAPRALLDRPLLDLDGARLRCADSGADARGEEAEAAGPELEASYVFFGLVLALIGLIFLMVLYLNRRGIQRWMRNLREACRDQMEGYHYRYEQDADPRRAPAPAAPAGSRATSPGSGL", "length": 382 }, "evidence": [ { "id": "F1N6L2", "url": "https://omabrowser.org/oma/group/F1N6L2/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "Q8C013-1", "protein_name": "Trophoblast glycoprotein-like", "gene_name": "Tpbgl", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MAPRAGQRGLWSPLPGLLLLAAALSRPAAPCPFQCYCFGSPRLMLRCASGAELRQPPRDVPPDARNLTIVGANLTVLRAAAFAGGGEGATDGVRLPLLTALRLTHNNIEVVEDGAFDGLPSLAALDLSHNPLRALGYRAFRGLPALRSLQLNHALARGSPGMLDALDAALAPLAELRLLGLVGNALSRLPLAALRLPRLEQLDARVNALAGLGPDELSALERDGDLPQPRLLLADNPLSCGCTSRPLLAWLHNATERVPDARRLRCASPRVLLDRPLIDLDEARLGCSDGDAHESGEGIDVAGPELEASYVFFGLVLALIGLIFLMVLYLNRRGIQRWMHNLREACRDQMEGYHYRYEQDADPRRAPAPAAPAGSRATSPGSGL", "length": 384 }, "evidence": [ { "id": "F1N6L2", "url": "https://omabrowser.org/oma/group/F1N6L2/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" } ], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 1, "go_terms": [ { "name": "plasma membrane", "id": "GO:0005886", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005886", "evidence": [ { "database": "UniProtKB", "id": "F1N6L2", "url": "https://www.uniprot.org/uniprotkb/F1N6L2" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 1, "go_terms": [ { "name": "negative regulation of canonical Wnt signaling pathway", "id": "GO:0090090", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0090090", "evidence": [ { "database": "UniProtKB", "id": "F1N6L2", "url": "https://www.uniprot.org/uniprotkb/F1N6L2" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 258, "end_pos": 260, "annotation": "n_glycosylation_sequon" }, { "start_pos": 67, "end_pos": 69, "annotation": "n_glycosylation_sequon" }, { "start_pos": 74, "end_pos": 76, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "F1N6L2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1N6L2" }, { "id": "SM00082", "database": "SMART", "url": "http://smart.embl.de/smart/do_annotation.pl?DOMAIN=SM00082" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "LRRCT", "eco_id": "ECO_0000259", "start_pos": 241, "end_pos": 293, "start_aa": "Asn", "end_aa": "Ala", "glycosite_overlap": [] } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "homologset.oma", "label": "OMA Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 258, "end_pos": 260 }, { "start_pos": 67, "end_pos": 69 }, { "start_pos": 74, "end_pos": 76 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": 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"total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ], "tool_support": { "graph_view": "yes" } }, { "uniprot_canonical_ac": "F1N6M5-1", "uniprot_ac": "F1N6M5", "uniprot_id": "F1N6M5_BOVIN", "mass": { "chemical_mass": 62388.0, "monoisotopic_mass": 62388.0 }, "refseq": { "ac": "NP_001030579", "name": "coiled-coil domain-containing protein 183", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001030579" }, "gene_names": [ { "name": "CCDC183", "type": "recommended", "evidence": [ { "id": "F1N6M5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1N6M5" } ] }, { "name": "CCDC183", "type": "synonym", "evidence": [ { "id": "NP_001030579", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001030579" } ] } ], "protein_names": [ { "name": "Coiled-coil domain containing 183", "type": "synonym", "evidence": [ { "id": "F1N6M5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1N6M5/entry#names_and_taxonomy" } ] }, { "name": "coiled-coil domain-containing protein 183", "type": "synonym", "evidence": [ { "id": "NP_001030579", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001030579" } ] } ], "function": [], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Bos taurus", "taxid": 9913, "evidence": [ { "database": "UniProtKB", "id": "F1N6M5", "url": "https://www.uniprot.org/uniprotkb/F1N6M5" } ], "common_name": "Bovine", "glygen_name": "Bovine", "reference_species": "Bos taurus [9913]" } ], "gene": [ { "name": "CCDC183", "url": "https://www.uniprot.org/uniprotkb/F1N6M5", "locus": { "chromosome": "11", "start_pos": 105908460, "end_pos": 105900332, "strand": "-", "evidence": [ { "database": "Ensembl Gene", "id": "ENSBTAG00000000933", "url": "https://www.ensembl.org/id/ENSBTAG00000000933" } ] } } ], "crossref": [ { "id": "F1N6M5", "url": "https://alphafold.ebi.ac.uk/entry/F1N6M5", "database": "AlphaFoldDB", "categories": [] }, { "id": "ENSBTAG00000000933", "url": "https://bgee.org/?page=gene&gene_id=ENSBTAG00000000933", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "618673", "url": "https://www.ncbi.nlm.nih.gov/gene/618673", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR043247", "url": "https://www.ebi.ac.uk/interpro/entry/IPR043247", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "bta:618673", "url": "https://www.genome.jp/dbget-bin/www_bget?bta:618673", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "RRGAHEW", "url": "https://omabrowser.org/oma/group/RRGAHEW/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "F1N6M5", "url": "https://www.orthodb.org/?gene=F1N6M5", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR47115", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR47115", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR47115:SF1", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR47115:SF1", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "NP_001030579", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001030579", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "F1N6M5", "url": "https://www.uniprot.org/uniprotkb/F1N6M5", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "F1N6M5-1", "url": "https://www.uniprot.org/uniprotkb/F1N6M5-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MKIRNEAEMEEQIQELKTITRLQEQCRALQIQSVKEKTVKNKATLALLRSNIRRRSQEWALAKKYDQWAISRACGKDVPMRLANSRCTMEVAREKLRKYVFDRVNVHNVLIHLVRRRGRKLESMQLELAGLKSQPDATKEELRLQQVIRQLENNIEKTTIKITTSQNIHFLYMDLLDHLKKKLAGYPTELDKLQNLVTNYCLELSDMTVMSQDAMMITDEVKMNMRQGEATFIEERRARENRLNQQKKLIDKIHTKETSEKYRRGRRDLDFPSNLMGPETLKVRKREASKADVEYQTNVTALVEKVKTAVQCSHLWDIAGRFLAQKGTEEDLELQMEDCEERRAQLEALMKKLEIEEATLKFRQTPSSVSFKSVEKKMNDMLKEEEERLQLAHSKMTKSQKLLLTIQTGIDNLYIRLIGIPLPTGQKEAVPSTTLDMYSKLAYCEGRLLYLADRVQMLAETEEVSTKVRDVLESSTLREKQNTRISFEETEEDVIETFQFADVDHSYVPSRAEIKRQGQRLIEEKLKVAKKKKK", "length": 534, "header": "tr|F1N6M5-1|F1N6M5_BOVIN Isoform 1 of Coiled-coil domain containing 183 OS=Bos taurus OX=9913 GN=CCDC183 PE=4 SV=2 CANONICAL=F1N6M5-1" }, "isoforms": [ { "isoform_ac": "F1N6M5-1", "url": "https://www.uniprot.org/uniprotkb/F1N6M5/entry", "sequence": { "sequence": "MKIRNEAEMEEQIQELKTITRLQEQCRALQIQSVKEKTVKNKATLALLRSNIRRRSQEWALAKKYDQWAISRACGKDVPMRLANSRCTMEVAREKLRKYVFDRVNVHNVLIHLVRRRGRKLESMQLELAGLKSQPDATKEELRLQQVIRQLENNIEKTTIKITTSQNIHFLYMDLLDHLKKKLAGYPTELDKLQNLVTNYCLELSDMTVMSQDAMMITDEVKMNMRQGEATFIEERRARENRLNQQKKLIDKIHTKETSEKYRRGRRDLDFPSNLMGPETLKVRKREASKADVEYQTNVTALVEKVKTAVQCSHLWDIAGRFLAQKGTEEDLELQMEDCEERRAQLEALMKKLEIEEATLKFRQTPSSVSFKSVEKKMNDMLKEEEERLQLAHSKMTKSQKLLLTIQTGIDNLYIRLIGIPLPTGQKEAVPSTTLDMYSKLAYCEGRLLYLADRVQMLAETEEVSTKVRDVLESSTLREKQNTRISFEETEEDVIETFQFADVDHSYVPSRAEIKRQGQRLIEEKLKVAKKKKK", "length": 534, "header": "tr|F1N6M5-1|F1N6M5_BOVIN Isoform 1 of Coiled-coil domain containing 183 OS=Bos taurus OX=9913 GN=CCDC183 PE=4 SV=2 CANONICAL=F1N6M5-1" }, "locus": { "chromosome": "11", "start_pos": 105908374, "end_pos": 105900381, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000042795.3", "url": 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"field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ], "tool_support": { "graph_view": "yes" } }, { "uniprot_canonical_ac": "F1N6X3-1", "uniprot_ac": "F1N6X3", "uniprot_id": "F1N6X3_BOVIN", "mass": { "chemical_mass": 24622.0, "monoisotopic_mass": 24622.0 }, "refseq": {}, "gene_names": [ { "name": "TMEM249", "type": "recommended", "evidence": [ { "id": "F1N6X3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1N6X3" } ] } ], "protein_names": [ { "name": "Transmembrane protein 249", "type": "synonym", "evidence": [ { "id": "F1N6X3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1N6X3/entry#names_and_taxonomy" } ] } ], "function": [], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Bos taurus", "taxid": 9913, "evidence": [ { "database": "UniProtKB", "id": "F1N6X3", "url": "https://www.uniprot.org/uniprotkb/F1N6X3" } ], "common_name": "Bovine", "glygen_name": "Bovine", "reference_species": "Bos taurus [9913]" } ], "gene": [ { "name": "TMEM249", "url": "https://www.uniprot.org/uniprotkb/F1N6X3", "locus": { "chromosome": "14", "start_pos": 586931, "end_pos": 584961, "strand": "-", "evidence": [ { "database": "Ensembl Gene", "id": "ENSBTAG00000035158", "url": "https://www.ensembl.org/id/ENSBTAG00000035158" } ] } } ], "crossref": [ { "id": "F1N6X3", "url": "https://alphafold.ebi.ac.uk/entry/F1N6X3", "database": "AlphaFoldDB", "categories": [] }, { "id": "ENSBTAG00000035158", "url": "https://bgee.org/?page=gene&gene_id=ENSBTAG00000035158", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "IPR027861", "url": "https://www.ebi.ac.uk/interpro/entry/IPR027861", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "F1N6X3", "url": "https://www.orthodb.org/?gene=F1N6X3", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR35442", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR35442", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR35442:SF1", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR35442:SF1", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF15158", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF15158", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "F1N6X3", "url": "https://www.uniprot.org/uniprotkb/F1N6X3", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "F1N6X3-1", "url": "https://www.uniprot.org/uniprotkb/F1N6X3-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "REGRGQSQGRGGAEARGWARAPGLACCCPIRLRNRRLDHDRGPGPTWGGLFRARALALPPQAASRSPLSSCVLAASPPVFVLEYYLDTLWKGTLLFIVCILLISFGLVSEGRTVCQGPMHLVYVRLALNSDAYRRCFFQLVLCGHKLEPLVLVQLSERYEQMEYLGRYIARKLNINYFDCLATSYRHVVRHWPLGTTFSPGIVLRKTGAYGGNPQWDPDV", "length": 220, "header": "tr|F1N6X3-1|F1N6X3_BOVIN Isoform 1 of Transmembrane protein 249 OS=Bos taurus OX=9913 GN=TMEM249 PE=4 SV=4 CANONICAL=F1N6X3-1" }, "isoforms": [ { "isoform_ac": "F1N6X3-1", "url": "https://www.uniprot.org/uniprotkb/F1N6X3/entry", "sequence": { "sequence": "REGRGQSQGRGGAEARGWARAPGLACCCPIRLRNRRLDHDRGPGPTWGGLFRARALALPPQAASRSPLSSCVLAASPPVFVLEYYLDTLWKGTLLFIVCILLISFGLVSEGRTVCQGPMHLVYVRLALNSDAYRRCFFQLVLCGHKLEPLVLVQLSERYEQMEYLGRYIARKLNINYFDCLATSYRHVVRHWPLGTTFSPGIVLRKTGAYGGNPQWDPDV", "length": 220, "header": "tr|F1N6X3-1|F1N6X3_BOVIN Isoform 1 of Transmembrane protein 249 OS=Bos taurus OX=9913 GN=TMEM249 PE=4 SV=4 CANONICAL=F1N6X3-1" }, "locus": { "chromosome": "14", "start_pos": 586594, "end_pos": 585298, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000049648.5", "url": "https://www.ensembl.org/id/ENSBTAT00000049648.5" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000046511.5", "url": "https://www.ensembl.org/id/ENSBTAP00000046511.5" } ] } } ], "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "other", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 46, "start_aa": "Thr", "end_pos": 46, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr46", "evidence": [ { "id": "", "database": "GlyGen", "url": "https://data.glygen.org/" } ], "filter_code": "000000000000000010000.00000000001000.0.01000" } ], "phosphorylation": [], "glycation": [], "keywords": [ "glycoprotein", "glycoprotein_predicted" ], "publication": [], "pathway": [], "orthologs": [], "go_annotation": {}, "pro_annotation": [], "site_annotation": [], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [ { "pdb_id": "AF-F1N6X3-F1", "pdb_chain": "global", "start_pos": 1, "end_pos": 220, "overlap": "1.0", "method": "AlphaFold", "type": "alphafold", "resolution": -1.0, "url": "https://data.glygen.org/ln2downloads/pdb/current/AF-F1N6X3-F1.pdb", "url_external": "https://alphafold.ebi.ac.uk/entry/F1N6X3" } ], "lectin_list": [], "domain_list": [], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [ 46 ], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 1 }, { "field": "total_sites", "count": 1 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 1 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "exact_sites", "count": 1 }, { "field": "exact_o_linked_sites", "count": 1 }, { "field": "fuzzy_sites", "count": 0 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_pos", "start_aa", "end_pos", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { 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{ "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ], "tool_support": { "graph_view": "yes" } }, { "uniprot_canonical_ac": "F1N705-1", "uniprot_ac": "F1N705", "uniprot_id": "F1N705_BOVIN", "mass": { "chemical_mass": 29921.0, "monoisotopic_mass": 29921.0 }, "refseq": {}, "gene_names": [ { "name": "MISP3", "type": "recommended", "evidence": [ { "id": "F1N705", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1N705" } ] } ], "protein_names": [ { "name": "MISP family member 3", "type": "synonym", "evidence": [ { "id": "F1N705", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1N705/entry#names_and_taxonomy" } ] } ], "function": [], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Bos taurus", "taxid": 9913, "evidence": [ { "database": "UniProtKB", "id": "F1N705", "url": "https://www.uniprot.org/uniprotkb/F1N705" } ], "common_name": "Bovine", "glygen_name": "Bovine", "reference_species": "Bos taurus [9913]" } ], "gene": [ { "name": "MISP3", "url": "https://www.uniprot.org/uniprotkb/F1N705", "locus": { "chromosome": "7", "start_pos": 11623029, "end_pos": 11625484, "strand": "+", "evidence": [ { "database": "Ensembl Gene", "id": "ENSBTAG00000016936", "url": "https://www.ensembl.org/id/ENSBTAG00000016936" } ] } } ], "crossref": [ { "id": "F1N705", "url": "https://alphafold.ebi.ac.uk/entry/F1N705", "database": "AlphaFoldDB", "categories": [] }, { "id": "ENSBTAG00000016936", "url": "https://bgee.org/?page=gene&gene_id=ENSBTAG00000016936", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "IPR029304", "url": "https://www.ebi.ac.uk/interpro/entry/IPR029304", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR042779", "url": "https://www.ebi.ac.uk/interpro/entry/IPR042779", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "bta:539805", "url": "https://www.genome.jp/dbget-bin/www_bget?bta:539805", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "F1N705", "url": "https://www.orthodb.org/?gene=F1N705", "database": "OrthoDB", "categories": [ 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"METPIEREIRRSCEREESLRRSRGLSPGRAGSELVELRVRPVLSLPGPSPALPRALERARAGAQMQRDIEREAYRQAALARPEVPKQRTRPPPQPLGELKRFFEAAGGCSSSPAAEGSADAQRLPEPGGRPHSVVQGRCPVLPRAPPPIAQSLLEQEVREVNERERELQRQRLSLYGTAEFKEPAPSLTVSRGDGKLAVIWPPRRKASENGLEQDQPASPCARNCVGTEET", "length": 231, "header": "tr|A0ABI0NW84-1|A0ABI0NW84_BOVIN Computationally mapped isoform of MISP family member 3 OS=Bos taurus OX=9913 GN=MISP3 PE=4 SV=1 CANONICAL=F1N705-1" }, "locus": { "chromosome": "7", "start_pos": 11625285, "end_pos": 11613539, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000137124.1", "url": "https://www.ensembl.org/id/ENSBTAT00000137124.1" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000104008.1", "url": "https://www.ensembl.org/id/ENSBTAP00000104008.1" } ] } }, { "isoform_ac": "A0ABI0P2J1-1", "url": "https://www.uniprot.org/uniprotkb/A0ABI0P2J1/entry", "sequence": { "sequence": "METPIEREIRRSCEREESLRRSRGLSPGRAGSELVELRVRPVLSLPGPSPALPRALERARAGAQMQRDIEREAYRQAALARPEVPKQRTRPPPQPLGELKRFFEAAGGCSSSPAAEGSADAQRLPEPGGRPHSVVQGRCPVLPRAPPPIAQSLLEQEVREVNERERELQRQRLSLYGTAEFKEPAPSLTVSRGDGKLAVIWPPRRKASENGLEQSKAKVKLRVPKLECLTALPPARAPDTSGGYSDLPKP", "length": 250, "header": "tr|A0ABI0P2J1-1|A0ABI0P2J1_BOVIN Computationally mapped isoform of MISP family member 3 OS=Bos taurus OX=9913 GN=MISP3 PE=4 SV=1 CANONICAL=F1N705-1" }, "locus": { "chromosome": "7", "start_pos": 11625285, "end_pos": 11619111, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000153137.1", "url": "https://www.ensembl.org/id/ENSBTAT00000153137.1" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000104893.1", "url": "https://www.ensembl.org/id/ENSBTAP00000104893.1" } ] } }, { "isoform_ac": "F1N705-1", "url": "https://www.uniprot.org/uniprotkb/F1N705/entry", "sequence": { "sequence": "METPIEREIRRSCEREESLRRSRGLSPGRAGSELVELRVRPVLSLPGPSPALPRALERARAGAQMQRDIEREAYRQAALARPEVPKQRTRPPPQPLGELKRFFEAAGGCSSSPAAEGSADAQRLPEPGGRPHSVVQGRCPVLPRAPPPIAQSLLEQEVREVNERERELQRQRLSLYGTAEFKEPAPSLTGKPPASQRWGFPGLQPLSPTPQLQWSSNPQGPPSWLPNSPDTPLDSPLSAHPFWTDLPLCSTPTFVGVPDTPHLGLWWGKGAGS", "length": 273, "header": "tr|F1N705-1|F1N705_BOVIN Isoform 1 of MISP family member 3 OS=Bos taurus OX=9913 GN=MISP3 PE=4 SV=4 CANONICAL=F1N705-1" }, "locus": { "chromosome": "7", "start_pos": 11623602, "end_pos": 11623286, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000022526.7", "url": "https://www.ensembl.org/id/ENSBTAT00000022526.7" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000022526.6", "url": "https://www.ensembl.org/id/ENSBTAP00000022526.6" } ] } } ], "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "other", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 209, "start_aa": "Thr", "end_pos": 209, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr209", "evidence": [ { "id": "", "database": "GlyGen", "url": "https://data.glygen.org/" } ], "filter_code": "000000000000000010000.00000000001000.0.01000" } ], "phosphorylation": [], "glycation": [], "keywords": [ "glycoprotein", "glycoprotein_predicted" ], "publication": [], "pathway": [ { "id": "bta:539805", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?bta:539805", "resource": "KEGG Pathway" } ], "orthologs": [], "go_annotation": {}, "pro_annotation": [], "site_annotation": [], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [ { "pdb_id": "AF-F1N705-F1", "pdb_chain": "global", "start_pos": 1, "end_pos": 273, "overlap": "1.0", "method": "AlphaFold", "type": "alphafold", "resolution": -1.0, "url": "https://data.glygen.org/ln2downloads/pdb/current/AF-F1N705-F1.pdb", "url_external": "https://alphafold.ebi.ac.uk/entry/F1N705" } ], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "F1N705", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1N705" }, { "id": "PF15304", "database": "Pfam", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF15304" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "A-kinase anchor protein 2 C-terminal", "eco_id": "ECO_0000259", "start_pos": 37, "end_pos": 149, "start_aa": "Leu", "end_aa": "Ile", "glycosite_overlap": [] } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [ 209 ], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 1 }, { "field": "total_sites", "count": 1 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 1 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "exact_sites", "count": 1 }, { "field": "exact_o_linked_sites", "count": 1 }, { "field": "fuzzy_sites", "count": 0 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_pos", "start_aa", "end_pos", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 1 }, { "field": "total_sites", "count": 1 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 1 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "exact_sites", "count": 1 }, { "field": "exact_o_linked_sites", "count": 1 }, { "field": "fuzzy_sites", "count": 0 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_pos", "start_aa", "end_pos", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ], "tool_support": { "graph_view": "yes" } }, { "uniprot_canonical_ac": "F1N708-1", "uniprot_ac": "F1N708", "uniprot_id": "F1N708_BOVIN", "mass": { "chemical_mass": 79816.0, "monoisotopic_mass": 79816.0 }, "refseq": { "ac": "XP_005215060", "name": "protein FAM83C", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_005215060" }, "gene_names": [ { "name": "FAM83C", "type": "recommended", "evidence": [ { "id": "F1N708", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1N708" } ] }, { "name": "FAM83C", "type": "synonym", "evidence": [ { "id": "XP_005215060", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_005215060" } ] } ], "protein_names": [ { "name": "Family with sequence similarity 83 member C", "type": "synonym", "evidence": [ { "id": "F1N708", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1N708/entry#names_and_taxonomy" } ] }, { "name": "protein FAM83C", "type": "synonym", "evidence": [ { "id": "XP_005215060", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_005215060" } ] } ], "function": [], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Bos taurus", "taxid": 9913, "evidence": [ { "database": "UniProtKB", "id": "F1N708", "url": "https://www.uniprot.org/uniprotkb/F1N708" } ], "common_name": "Bovine", "glygen_name": "Bovine", "reference_species": "Bos taurus [9913]" } ], "gene": [ { "name": "FAM83C", "url": "https://www.uniprot.org/uniprotkb/F1N708", "locus": { "chromosome": "13", "start_pos": 64554269, "end_pos": 64561037, "strand": "+", "evidence": [ { "database": "Ensembl Gene", "id": "ENSBTAG00000006278", "url": "https://www.ensembl.org/id/ENSBTAG00000006278" } ] } } ], "crossref": [ { "id": "F1N708", "url": "https://alphafold.ebi.ac.uk/entry/F1N708", "database": "AlphaFoldDB", "categories": [] }, { "id": "ENSBTAG00000006278", "url": "https://bgee.org/?page=gene&gene_id=ENSBTAG00000006278", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "101903690", "url": "https://www.ncbi.nlm.nih.gov/gene/101903690", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR012461", "url": "https://www.ebi.ac.uk/interpro/entry/IPR012461", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR050944", "url": "https://www.ebi.ac.uk/interpro/entry/IPR050944", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "bta:101903690", "url": "https://www.genome.jp/dbget-bin/www_bget?bta:101903690", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "DYMTSHV", "url": "https://omabrowser.org/oma/group/DYMTSHV/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "F1N708", "url": "https://www.orthodb.org/?gene=F1N708", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR16181", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR16181", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR16181:SF29", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR16181:SF29", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF07894", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF07894", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "XP_005215060", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_005215060", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "F1N708", "url": "https://www.uniprot.org/uniprotkb/F1N708", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "F1N708-1", "url": "https://www.uniprot.org/uniprotkb/F1N708-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MAGPLRSRVDELKRPWWRESSPLVLQHSEAARLAADALLERGEDAYLRVISEERELPFLSALDMEYMTSHARGGPELGEAQGPEALGPDRLSLHSEVTSGTYFPLASDIDPPDLDLGWPEVPHATGFSPTQAVVHFQRDKAKSIKDLLRFLFSQARTVVAVVMDIFTDMELLCDLMEASGRRGIPVYLLLAQQHLRHFLEMCYKMDLNGGHLPNMRVRSTCGDTYCSKAGRRFTGQALEKFVIIDCEQVVAGSYSFTWLCSQAHTSMVLQLRGRIVEDFDREFRCLYAESRPVEGFCGGEDPPSPRAPCPPPVALAFGPGVPSTTSSSPSSTSLSSIKRSPRMGHSYLALPGGGDRTDMGVGSSSPGPTRCEADGQPSLQRQLSDPNHGPLLGPYRANLSKLGASPWCQSSPALNHNSTSPVTLGGGSPLLACSRPLLPFPWSVSALPRLPENGVPGSQEPRRSRGRWVPSTALETLEENKASLSQSHGQLDLLVPFSRAREAGGPDLGVARNSGSLWPGEQASEDRRLAPNQRYNQLDFLPQAQGARGAPESGSPKVGSWTPEDKRLSANHSHGQLDLLVQFPQPGGSRVPLEANSPARAGKQRPDERRQTLGHSQLDLITKFGPLRGEGPEPSELPRPSPAQKAGVDLGEEKRRTLGHSQLDLITKYHQLQGARQGPEPSLSGGPAGGQRNGNSNGLSEDEKRRTLGHSKLDLITKYNKSKFKLLRSRFET", "length": 733, "header": "tr|F1N708-1|F1N708_BOVIN Isoform 1 of Family with sequence similarity 83 member C OS=Bos taurus OX=9913 GN=FAM83C PE=3 SV=2 CANONICAL=F1N708-1" }, "isoforms": [ { "isoform_ac": "F1N708-1", "url": "https://www.uniprot.org/uniprotkb/F1N708/entry", "sequence": { "sequence": "MAGPLRSRVDELKRPWWRESSPLVLQHSEAARLAADALLERGEDAYLRVISEERELPFLSALDMEYMTSHARGGPELGEAQGPEALGPDRLSLHSEVTSGTYFPLASDIDPPDLDLGWPEVPHATGFSPTQAVVHFQRDKAKSIKDLLRFLFSQARTVVAVVMDIFTDMELLCDLMEASGRRGIPVYLLLAQQHLRHFLEMCYKMDLNGGHLPNMRVRSTCGDTYCSKAGRRFTGQALEKFVIIDCEQVVAGSYSFTWLCSQAHTSMVLQLRGRIVEDFDREFRCLYAESRPVEGFCGGEDPPSPRAPCPPPVALAFGPGVPSTTSSSPSSTSLSSIKRSPRMGHSYLALPGGGDRTDMGVGSSSPGPTRCEADGQPSLQRQLSDPNHGPLLGPYRANLSKLGASPWCQSSPALNHNSTSPVTLGGGSPLLACSRPLLPFPWSVSALPRLPENGVPGSQEPRRSRGRWVPSTALETLEENKASLSQSHGQLDLLVPFSRAREAGGPDLGVARNSGSLWPGEQASEDRRLAPNQRYNQLDFLPQAQGARGAPESGSPKVGSWTPEDKRLSANHSHGQLDLLVQFPQPGGSRVPLEANSPARAGKQRPDERRQTLGHSQLDLITKFGPLRGEGPEPSELPRPSPAQKAGVDLGEEKRRTLGHSQLDLITKYHQLQGARQGPEPSLSGGPAGGQRNGNSNGLSEDEKRRTLGHSKLDLITKYNKSKFKLLRSRFET", "length": 733, "header": "tr|F1N708-1|F1N708_BOVIN Isoform 1 of Family with sequence similarity 83 member C OS=Bos taurus OX=9913 GN=FAM83C PE=3 SV=2 CANONICAL=F1N708-1" }, "locus": { "chromosome": "13", "start_pos": 64560838, "end_pos": 64555273, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000008235.7", "url": "https://www.ensembl.org/id/ENSBTAT00000008235.7" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000008235.6", "url": "https://www.ensembl.org/id/ENSBTAP00000008235.6" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [ { "id": "bta:101903690", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?bta:101903690", "resource": "KEGG Pathway" } ], "orthologs": [ { "uniprot_canonical_ac": "A2ARK0-1", "protein_name": "Protein FAM83C", "gene_name": "Fam83c", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MQGCQAGASIFFLIAANPDANHGASGGLGSRWIRTFSRIAPAGTQGMAGPLRSRVEELKRPWWRESSPLVLQHSEAARLAADALLERGEAAYLQVISEERELPFLSALDVDYMISHVRGVPELSEAQGSETLGQDLSMLSEVTSGTYFPMASDLDPPDLDLGWPEVPQATGFSPTQAVVHFQRDKGKSIKDLLRFLFSQAQTVVAVVMDVFTDMELLCDLMEASSRRGVPVYLLLAQEHLKYFLEMCYKMDLNGGHLVNMRVRSTCGDTYCSKAGRRFTGQALEKFVIIDCEQVVAGSYSFTWLCSQAHTSMVLQLRGHIVEDFDREFRCLYAESQPVEGFCSNEDPLMPQVPRPPPVTLAFGPAVPSATGSSPSSNSLSSIKHSPLLARSSYLALPGGGGRNDMGMGSSSPGPAYHEAGGQPSLYRQLSDPNHISPPGPYRANLSKLGASPWSQSSPALNHSSTSPLTLAVGSPLLPSSRPLLHFTRGVPALSRLPENGLPASQDPSLPRGRWVPGTALETVEEKKVSLSQSHDHLDRLSPFSKAGEAGGPNSRVTPDSSSLQHRELALDDRRLSLSHSHSQLDLLSQGQGVLESGSLRPGELSLENRKLSLNHNHGQLDLLPQNPKPQAPKIPSDAYSSAGPSKPSLDDRRQTLGHSQLDLITKFGPFRSEGPGPSCPPEPSPVRMAGVGSADEKRLTLGHSKLDLITKYHQLQGARQKPEPGIPGAPVSGHQNGSSNDLFAPEKRLTLGHSKLDLITKYNKSKFKQLRSRFES", "length": 776 }, "evidence": [ { "id": "F1N708", "url": "https://omabrowser.org/oma/group/F1N708/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "M0R501-1", "protein_name": "Family with sequence similarity 83, member C", "gene_name": "Fam83c", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MLGCQAGSSIFFLIAANPGASHGASCGLGSRWMQTFSRIVQAGTQGMAGPLRSRVEELKRPWWRESSPLVLQHSEAARLAADALLERGEAAYLQVISEERELPFLSALDVDYMISHVRGVPELSEAQGSETLGQDRLSMLSEVTSGTYFPMASDLDPPDLDLGWPEVPQATGFSPTQAVVHFQRDKGKSIKDLLRFLFSQAHTVVAVVMDVFTDMELLCDLMEASSRRGVPVYLLLAQEHLKYFLEMCYKMDLNGGHLVNMRVRSTCGDTYCSKAGRRFTGQALEKFVIIDCEQVVAGSYSFTWLCSQAHTSMVLQLRGHIVEDFDREFRCLYAESQPVEGFCGNEDPLISQVPCPPPVTLAFGPGIPSPTGSSPSSNSLSSIKHSPLLARSSYLALPGGGGCSDMGMGSSSPGPAHHEAGAQPSLYRQLSDPNHISTPGPYRANLSKLGSSPWSQSSPALNHSSTSPLTLGVGSPLLPSSRPLLHFTRGVPALSRLPENGLPASQDPCLPRGRWVPGTALETVDEKKVSLSQSHDRLDRLIPFPKAGEAGVPSSRVSPNSSSLQHGEQVLDDRRLSLSHSYSQLDLLSQGQGSPESGSLRPGELSPEDRKLSLNHSHGPLDLLPQNPKPQASKIPPDAHSSARPGKPSVDDRRQTLGHSQLDLITKFGPFRSEGPGPSCPPEASPVRMAGVGSADEKRLTLGHSKLDLITKYHQLQGARQKPESGTPGAPISGQQNGSGNDLFAPEKRLTLGHSKLDLITKYNKSKFKQLRSRFES", "length": 777 }, "evidence": [ { "id": "F1N708", "url": "https://omabrowser.org/oma/group/F1N708/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "Q9BQN1-1", "protein_name": "Protein FAM83C", "gene_name": "FAM83C", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MFGGPGPGVLGAQGMAGPLRGRVEELKLPWWRESSPLVLRHSEAARLAADALLERGEAAYLRVISEERELPFLSALDVDYMTSHVRGGPELSEAQGQEASGPDRLSLLSEVTSGTYFPMASDIDPPDLDLGWPEVPQATGFSPTQAVVHFQRDKAKNIKDLLRFLFSQAHTVVAVVMDIFTDMELLCDLMEASSRRGVPVYLLLAQEHLRHFLEMCYKMDLNGEHLPNMRVRSTCGDTYCSKAGRRFTGQALEKFVLIDCEQVVAGSYSFTWLCSQAHTSMVLQLRGRIVEDFDREFRCLYAESQPVEGFCGGEDPLSPRALRPPPVALAFRPDVPSPTSSLPSSTSLSSIKQSPLMGRSSYLALPGGGDCSDTGVVSSSLGPARREASGQPSLHRQLSDPNHGSPPGLYRANLGKLGAYPWSQSSPALNHNSTSPLTLAVGSPLLPRSRPLLQFHRGAPALSRFPENGLPGSQEPSPLRGRWVPGTTLETVEEKEKKASPSQSRGQLDLLVPFPRAREVGDPDSGVTPNSGPLRPGEQAPEDRRLSPSQADSQLDLLSRALGTGGAPELGSLRPGDRALEDRRLSLNQSRGQSDLLMQYPKAQGSRVPLETNSSARPARRAPDERRQTLGHSQLDLITKFGPFRGEGPGPNGLPISSPARTAGAGSGDEKRLTLGHSKLDLITKYHQLHGARQGTEPGGPKGGHLNGGNSDLVRDEKRLTLGHSKLDLITKYNKSKFKQLRSRFES", "length": 747 }, "evidence": [ { "id": "F1N708", "url": "https://omabrowser.org/oma/group/F1N708/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" } ], "go_annotation": { "categories": [ { "name": "Cellular Component", 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"tr|F1N748-1|F1N748_BOVIN Isoform 1 of G protein regulated inducer of neurite outgrowth 1 OS=Bos taurus OX=9913 GN=GPRIN1 PE=4 SV=5 CANONICAL=F1N748-1" }, "isoforms": [ { "isoform_ac": "F1N748-1", "url": "https://www.uniprot.org/uniprotkb/F1N748/entry", "sequence": { "sequence": 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"tr|F1N748-1|F1N748_BOVIN Isoform 1 of G protein regulated inducer of neurite outgrowth 1 OS=Bos taurus OX=9913 GN=GPRIN1 PE=4 SV=5 CANONICAL=F1N748-1" }, "locus": { "chromosome": "7", "start_pos": 38073214, "end_pos": 38070326, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000061410.4", "url": "https://www.ensembl.org/id/ENSBTAT00000061410.4" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000053673.4", "url": "https://www.ensembl.org/id/ENSBTAP00000053673.4" } ] } } ], "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "other", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 205, "start_aa": "Thr", "end_pos": 205, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr205", "evidence": [ { "id": "", "database": "GlyGen", "url": "https://data.glygen.org/" } ], "filter_code": "000000000000000010000.00000000001000.0.01000" }, { "glytoucan_ac": "", "type": "O-linked", "subtype": "other", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 961, "start_aa": "Thr", "end_pos": 961, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr961", "evidence": [ { "id": "", "database": "GlyGen", "url": "https://data.glygen.org/" } ], "filter_code": "000000000000000010000.00000000001000.0.01000" } ], "phosphorylation": [], "glycation": [], "keywords": [ "glycoprotein", "glycoprotein_predicted" ], "publication": [], "pathway": [], "orthologs": [], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 1, "go_terms": [ { "name": "plasma membrane", "id": "GO:0005886", "url": 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"method": "AlphaFold", "type": "alphafold", "resolution": -1.0, "url": "https://data.glygen.org/ln2downloads/pdb/current/AF-F1N7A3-F1.pdb", "url_external": "https://alphafold.ebi.ac.uk/entry/F1N7A3" } ], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "F1N7A3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1N7A3" }, { "id": "PF08079", "database": "Pfam", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF08079" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "Large ribosomal subunit protein uL30 N-terminal eukaryota", "eco_id": "ECO_0000259", "start_pos": 14, "end_pos": 85, "start_aa": "Val", "end_aa": "Ala", "glycosite_overlap": [] }, { "evidence": [ { "id": "F1N7A3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1N7A3" }, { "id": "PF00327", "database": "Pfam", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00327" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "Large ribosomal subunit protein uL30-like ferredoxin-like fold", "eco_id": "ECO_0000259", "start_pos": 90, "end_pos": 140, "start_aa": "Ala", "end_aa": "Ile", "glycosite_overlap": [] } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 119, "end_pos": 121 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ], "tool_support": { "graph_view": "yes" } }, { "uniprot_canonical_ac": "F1N7A7-1", "uniprot_ac": "F1N7A7", "uniprot_id": "F1N7A7_BOVIN", "mass": { "chemical_mass": 56481.0, "monoisotopic_mass": 56481.0 }, "refseq": {}, "gene_names": [ { "name": "SHE", "type": "recommended", "evidence": [ { "id": "F1N7A7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1N7A7" } ] } ], "protein_names": [ { "name": "SH2 domain-containing adapter protein E", "type": "recommended", "evidence": [ { "id": "F1N7A7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1N7A7/entry#names_and_taxonomy" } ] } ], "function": [], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Bos taurus", "taxid": 9913, "evidence": [ { "database": "UniProtKB", "id": "F1N7A7", "url": "https://www.uniprot.org/uniprotkb/F1N7A7" } ], "common_name": "Bovine", "glygen_name": "Bovine", "reference_species": "Bos taurus [9913]" } ], "gene": [ { "name": "SHE", "url": "https://www.uniprot.org/uniprotkb/F1N7A7", "locus": { "chromosome": "3", "start_pos": 16104559, "end_pos": 16086187, "strand": "-", "evidence": [ { "database": "Ensembl Gene", "id": "ENSBTAG00000020542", "url": "https://www.ensembl.org/id/ENSBTAG00000020542" } ] } } ], "crossref": [ { "id": "F1N7A7", "url": "https://alphafold.ebi.ac.uk/entry/F1N7A7", "database": "AlphaFoldDB", "categories": [] }, { "id": "ENSBTAG00000020542", "url": "https://bgee.org/?page=gene&gene_id=ENSBTAG00000020542", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "cd10391", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd10391", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "IPR000980", "url": "https://www.ebi.ac.uk/interpro/entry/IPR000980", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR035042", "url": "https://www.ebi.ac.uk/interpro/entry/IPR035042", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR036860", "url": "https://www.ebi.ac.uk/interpro/entry/IPR036860", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR051846", "url": "https://www.ebi.ac.uk/interpro/entry/IPR051846", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "WFKEFPM", "url": "https://omabrowser.org/oma/group/WFKEFPM/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "F1N7A7", "url": "https://www.orthodb.org/?gene=F1N7A7", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR15127", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR15127", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR15127:SF29", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR15127:SF29", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00017", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00017", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "F1N7A7", "url": "https://www.uniprot.org/uniprotkb/F1N7A7", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "F1N7A7-1", "url": "https://www.uniprot.org/uniprotkb/F1N7A7-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MQWPPVPGASPCLSWASSLACSAATTLLSRAGRAPLMAAKWFKEFPLNLKTVSERAKPGGGGGGKLRKNSETGGSGPAPGKGRKNSAAELGSGRAGVGPAKDSRLSRDSLQGLIQAAAGKGRKNSRATEEEPHRGAAKSSGCSTYINRLIKVDTQEKNGKSNYPSSSSSSSSSSSSSSSASSSPSSLGPELDKGKIIKQQDTVIILEDYADPYDAKRTKGQRDAERVGENDGYMEPYDAQQMITEIRRRGSKDPLVKALQLLDSPCEPGENGPKPEALTKRRSSKELLGKSPQLYDTPYEPAAEAGPFAAEGPERKARLPPDSHGRLPQDDERPAAEYEQPWEWKKEQIVRALSVQFEGSERPSVKEEAARQHHRQKSWTQKILKPALTDHSEGERVDPALPLEKQPWYHGAITRAEAESRLQSCKEAAYLVRNSESGTSRYSIALKTSQGCVHIIVAQTKDNKYTLNQTSAVFGSIPEVVHYYSSEKLPFKGAEHMTLLYPVHSKLHQGPASKSPSGASHT", "length": 522, "header": "tr|F1N7A7-1|F1N7A7_BOVIN Isoform 1 of SH2 domain-containing adapter protein E OS=Bos taurus OX=9913 GN=SHE PE=4 SV=1 CANONICAL=F1N7A7-1" }, "isoforms": [ { "isoform_ac": "F1N7A7-1", "url": "https://www.uniprot.org/uniprotkb/F1N7A7/entry", "sequence": { "sequence": "MQWPPVPGASPCLSWASSLACSAATTLLSRAGRAPLMAAKWFKEFPLNLKTVSERAKPGGGGGGKLRKNSETGGSGPAPGKGRKNSAAELGSGRAGVGPAKDSRLSRDSLQGLIQAAAGKGRKNSRATEEEPHRGAAKSSGCSTYINRLIKVDTQEKNGKSNYPSSSSSSSSSSSSSSSASSSPSSLGPELDKGKIIKQQDTVIILEDYADPYDAKRTKGQRDAERVGENDGYMEPYDAQQMITEIRRRGSKDPLVKALQLLDSPCEPGENGPKPEALTKRRSSKELLGKSPQLYDTPYEPAAEAGPFAAEGPERKARLPPDSHGRLPQDDERPAAEYEQPWEWKKEQIVRALSVQFEGSERPSVKEEAARQHHRQKSWTQKILKPALTDHSEGERVDPALPLEKQPWYHGAITRAEAESRLQSCKEAAYLVRNSESGTSRYSIALKTSQGCVHIIVAQTKDNKYTLNQTSAVFGSIPEVVHYYSSEKLPFKGAEHMTLLYPVHSKLHQGPASKSPSGASHT", "length": 522, "header": "tr|F1N7A7-1|F1N7A7_BOVIN Isoform 1 of SH2 domain-containing adapter protein E OS=Bos taurus OX=9913 GN=SHE PE=4 SV=1 CANONICAL=F1N7A7-1" }, "locus": { "chromosome": "3", "start_pos": 16103401, "end_pos": 16086360, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000027370.5", "url": "https://www.ensembl.org/id/ENSBTAT00000027370.5" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000027370.4", "url": "https://www.ensembl.org/id/ENSBTAP00000027370.4" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [], "orthologs": [ { "uniprot_canonical_ac": "A0A8I5Y6C5-1", "protein_name": "SH2 domain-containing adapter protein E", "gene_name": "She", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MRRPPAPGAPWCLGWASSLVCSAASTLPGPLMAAKWFKEFPLTLKTASERARPGGAGGKPRKNSETGSAAPTPGKGRKNSAAELGGSRTGSGPPKDSRLSRDSLQGLIQAAAGKGRKNSRVTTTATASASATTTEEEPHRGAVAKSAGCSTYISRLIKVDTQEKNGKSIYPGGGSTSSSSSSSSSASSSPSSLGPELDKTKIMRQQDTVIILEDYADPYDAKRTKGQRDAERVGENDGYMEPYDAQQMITAASRIGNEEKAVGLKVKRLGQKTRLWPQTAWTPDLVSEIRRRGSKDPLVKALQLLDGPCEPGETMKVEATAKRRSSKDLLGKPPQLYDTPYEPSEGDLRAAEVKARPADGRLPEEDDRPAAEYEQPWEWKREQIARALSVQFEGSDRSPGREEAGRPQHWQKTLKPTLSDHGDGEKVDPGLALEKQPWYHGSISRAEAESRLQPCKEAGYLVRNSESGNSKYSIALKTSQGCVHIIVAQTKDSRYTLNQTSAVFDSIPEVVHYYSTAKLPFKGAEHMTLLHPVHKLH", "length": 537 }, "evidence": [ { "id": "F1N7A7", "url": "https://omabrowser.org/oma/group/F1N7A7/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "F1RGM4-1", "protein_name": "SH2 domain-containing adapter protein E", "gene_name": "SHE", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MQWPPAPGASLCLGWASSLACSAATTLLSRAGWAPVMAAKWFKEFPLNLKTVSERAKPGGGAGGKLRKNSEAGGAGPAPGKGRKNSAAELGSGRAGVGPPKDSRLSRDSLQGLIQAAAGKGRKNSRAAEEEPHRGAAKSTGCSTYINRLIKVDTQEKNGKTNYPSSSSSSSSSSSSSSSASSSPSSLGPELDKGKIIKQQDTVIILEDYADPYDAKRTKGQRDAERVGENDGYMEPYDAQQMITEIRRRGSKDPLVKALQLLDSPCEPGENGLKPEALAKRRGSKELAGKPPQLYDTPYEPAAEGVPRAEAPERKARPPDGHSRLPQDDERPAAEYEQPWEWKKEQIVRALSVQFEGSERPSIKEESVRQHHRQKSWTQKILKPSLSDHSEGERVDPALPLEKQPWYHGAITRAEAESRLQPCKEAGYLVRNSESGTSRYSIALKTSQGCVHIIVAQTKDNKYTLNQTSAVFDSIPEVVHYYSNEKLPFKGAEHMTLLYPVHSKLH", "length": 506 }, "evidence": [ { "id": "F1N7A7", "url": "https://omabrowser.org/oma/group/F1N7A7/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "Q5VZ18-1", "protein_name": "SH2 domain-containing adapter protein E", "gene_name": "SHE", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MQWSPTPGASACLGWASSLACSTAPTLLGRAGRGPLMAAKWFKEFPLNLKTVSERAKPGGGGGKLRKNSEAGGAGPGPGKGRKNSAAELGSGRAGVGPKDSRLSRDSLQGLIQAAAGKGRKNSRATEEEPHRGATKSSGCSTYINRLIKVDTQEKNGKSNYPSSSSSSSSSSSSASSSPSSLGPELDKGKIIKQQETVIILEDYADPYDAKRTKGQRDAERVGENDGYMEPYDAQQMITEIRRRGSKDPLVKALQLLDSPCEPADGGLKSETLAKRRSSKDLLGKPPQLYDTPYEPAEGGPRAEGKARPPDSRLPENDERPAAEYEQPWEWKKEQIVRALSVQFEGAERPSFREETVRQHHRQKSWTQKILKPALSDHSEGEKVDPGLPLEKQPWYHGAISRAEAESRLQPCKEAGYLVRNSESGNSRYSIALKTSQGCVHIIVAQTKDNKYTLNQTSAVFDSIPEVVHYYSNEKLPFKGAEHMTLLYPVHSKLH", "length": 495 }, "evidence": [ { "id": "F1N7A7", "url": "https://omabrowser.org/oma/group/F1N7A7/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "Q8BSD5-1", "protein_name": "SH2 domain-containing adapter protein E", "gene_name": "She", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MRRPPAPGAPRCLSWASSLFCSAASTLPGPLMAAKWFKEFPLTLKTASERARPGGAGGKPRKNSETGGAAPTPGKGRKNSAAELGASKASSGPPKDSRLSRDSLQGLIQAAAGKGRKNSRVTATATEEEPHRGAVTKSAGCSTYISRLIKVDTQEKNGKSAYPGGGSTSSSSSSSSSASSSPSSLGPELDKAKIMRQQDTVIILEDYADPYDAKRTKGQRDAERVGENDGYMEPYDAQQMITEIRRRGSKDPLVKALQLLDGPSEPGETVKVEATAKRRSSKDLLGKPPQLYDTPYEPSEGGQRVAEVKTRPADSRLPEEDDRPAAEYEQPWEWKREQIARALSVQFEGSDRPPGREDAGRPHHWQKTLKPTLSDHGDGEKVDPGLALEKQPWYHGSISRAEAESRLQPCKEAAYLVRNSESGNSKYSIALKTSQGCVHIIVAQTKDNKYTLNQTSAVFDSIPEVVHYYSNAKLPFKGAEHMTLLHPVHKLH", "length": 492 }, "evidence": [ { "id": "F1N7A7", "url": "https://omabrowser.org/oma/group/F1N7A7/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" } ], "go_annotation": { "categories": [ { "name": "Molecular Function", "total": 1, "go_terms": [ { "name": "phosphotyrosine residue binding", "id": "GO:0001784", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0001784", "evidence": [ { "database": "UniProtKB", "id": "F1N7A7", "url": "https://www.uniprot.org/uniprotkb/F1N7A7" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 468, "end_pos": 470, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [ { "pdb_id": "AF-F1N7A7-F1", "pdb_chain": "global", "start_pos": 1, "end_pos": 522, "overlap": "1.0", "method": "AlphaFold", "type": "alphafold", "resolution": -1.0, "url": "https://data.glygen.org/ln2downloads/pdb/current/AF-F1N7A7-F1.pdb", "url_external": "https://alphafold.ebi.ac.uk/entry/F1N7A7" } ], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "F1N7A7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1N7A7" }, { "id": "PS50001", "database": "PROSITE", "url": "https://prosite.expasy.org/PS50001" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "SH2", "eco_id": "ECO_0000259", "start_pos": 408, "end_pos": 503, "start_aa": "Trp", "end_aa": "Val", "glycosite_overlap": [] } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "homologset.oma", "label": "OMA Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 468, "end_pos": 470 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ], "tool_support": { "graph_view": "yes" } }, { "uniprot_canonical_ac": "F1N7B6-1", "uniprot_ac": "F1N7B6", "uniprot_id": "F1N7B6_BOVIN", "mass": { "chemical_mass": 12550.0, "monoisotopic_mass": 12550.0 }, "refseq": { "ac": "NP_001033191", "name": "protein preY, mitochondrial precursor", "summary": "The product of this gene, which is well-conserved, is encoded by the same bicistronic transcript that encodes phosphatidylinositol glycan anchor biosynthesis, class Y, but the two proteins are unrelated. This gene represents the protein encoded by the upstream open reading frame, while the protein encoded by the downstream open reading frame is represented by GeneID:514374. [provided by RefSeq, Aug 2012].", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001033191" }, "gene_names": [ { "name": "PYURF", "type": "recommended", "evidence": [ { "id": "F1N7B6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1N7B6" } ] }, { "name": "PREY", "type": "synonym", "evidence": [ { "id": "NP_001033191", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001033191" } ] }, { "name": "PYURF", "type": "synonym", "evidence": [ { "id": "NP_001033191", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001033191" } ] } ], "protein_names": [ { "name": "Protein preY, mitochondrial", "type": "recommended", "evidence": [ { "id": "F1N7B6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1N7B6/entry#names_and_taxonomy" } ] }, { "name": "PIGY upstream reading frame", "type": "synonym", "evidence": [ { "id": "NP_001033191", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001033191" } ] }, { "name": "protein preY, mitochondrial precursor", "type": "synonym", "evidence": [ { "id": "NP_001033191", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001033191" } ] }, { "name": "protein preY, mitochondrial", "type": "synonym", "evidence": [ { "id": "NP_001033191", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001033191" } ] } ], "function": [ { "annotation": "The product of this gene, which is well-conserved, is encoded by the same bicistronic transcript that encodes phosphatidylinositol glycan anchor biosynthesis, class Y, but the two proteins are unrelated. This gene represents the protein encoded by the upstream open reading frame, while the protein encoded by the downstream open reading frame is represented by GeneID:514374. [provided by RefSeq, Aug 2012].", "evidence": [ { "database": "RefSeq", "id": "NP_001033191", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001033191" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Bos taurus", "taxid": 9913, "evidence": [ { "database": "UniProtKB", "id": "F1N7B6", "url": "https://www.uniprot.org/uniprotkb/F1N7B6" } ], "common_name": "Bovine", "glygen_name": "Bovine", "reference_species": "Bos taurus [9913]" } ], "gene": [ { "name": "PYURF", "url": "https://www.uniprot.org/uniprotkb/F1N7B6", "locus": { "chromosome": "6", "start_pos": 36253479, "end_pos": 36250626, "strand": "-", "evidence": [ { "database": "Ensembl Gene", "id": "ENSBTAG00000020541", "url": "https://www.ensembl.org/id/ENSBTAG00000020541" } ] } } ], "crossref": [ { "id": "F1N7B6", "url": "https://alphafold.ebi.ac.uk/entry/F1N7B6", "database": "AlphaFoldDB", "categories": [] }, { "id": "ENSBTAG00000020541", "url": "https://bgee.org/?page=gene&gene_id=ENSBTAG00000020541", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "100996942", "url": "https://www.ncbi.nlm.nih.gov/gene/100996942", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR005651", "url": "https://www.ebi.ac.uk/interpro/entry/IPR005651", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "bta:100996942", "url": "https://www.genome.jp/dbget-bin/www_bget?bta:100996942", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "RMIHQNK", "url": "https://omabrowser.org/oma/group/RMIHQNK/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "F1N7B6", "url": "https://www.orthodb.org/?gene=F1N7B6", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR33505", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR33505", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR33505:SF4", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR33505:SF4", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF03966", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF03966", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "R-BTA-6799198", "url": "https://www.reactome.org/PathwayBrowser/#R-BTA-6799198", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "NP_001033191", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001033191", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "F1N7B6", "url": "https://www.uniprot.org/uniprotkb/F1N7B6", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "F1N7B6-1", "url": "https://www.uniprot.org/uniprotkb/F1N7B6-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MLSGVCARLASALRGTRAPPSAVALRCLHASSSRPSADKSDRTEKPPRAFDQALLEFLVCPLSKKPLRYEASTNELINEELGIAYPIIDGIPNMIPQAARMTHQNKKQEEVEQH", "length": 114, "header": "tr|F1N7B6-1|F1N7B6_BOVIN Isoform 1 of Protein preY, mitochondrial OS=Bos taurus OX=9913 GN=PYURF PE=3 SV=1 CANONICAL=F1N7B6-1" }, "isoforms": [ { "isoform_ac": "F1N7B6-1", "url": "https://www.uniprot.org/uniprotkb/F1N7B6/entry", "sequence": { "sequence": "MLSGVCARLASALRGTRAPPSAVALRCLHASSSRPSADKSDRTEKPPRAFDQALLEFLVCPLSKKPLRYEASTNELINEELGIAYPIIDGIPNMIPQAARMTHQNKKQEEVEQH", "length": 114, "header": "tr|F1N7B6-1|F1N7B6_BOVIN Isoform 1 of Protein preY, mitochondrial OS=Bos taurus OX=9913 GN=PYURF PE=3 SV=1 CANONICAL=F1N7B6-1" }, "locus": { "chromosome": "6", "start_pos": 36252585, "end_pos": 36250728, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000027369.5", "url": "https://www.ensembl.org/id/ENSBTAT00000027369.5" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000027369.2", "url": "https://www.ensembl.org/id/ENSBTAP00000027369.2" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [ { "id": "bta:100996942", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?bta:100996942", "resource": "KEGG Pathway" }, { "id": "R-BTA-6799198", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-BTA-6799198", "resource": "Reactome", "description": "Complex I biogenesis" } ], "orthologs": [ { "uniprot_canonical_ac": "Q96I23-1", "protein_name": "Protein preY, mitochondrial", "gene_name": "PYURF", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MLSGARCRLASALRGTRAPPSAVARRCLHASGSRPLADRGKKTEEPPRDFDPALLEFLVCPLSKKPLRYEASTNELINEELGIAYPIIDGIPNMIPQAARMTRQSKKQEEVEQR", "length": 114 }, "evidence": [ { "id": "F1N7B6", "url": "https://omabrowser.org/oma/group/F1N7B6/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" } ], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 2, "go_terms": [ { "name": "mitochondrion", "id": "GO:0005739", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005739", "evidence": [ { "database": "UniProtKB", "id": "F1N7B6", "url": "https://www.uniprot.org/uniprotkb/F1N7B6" } ], "pmid": "" }, { "name": "endoplasmic reticulum membrane", "id": "GO:0005789", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005789", "evidence": [ { "database": "UniProtKB", "id": "F1N7B6", "url": "https://www.uniprot.org/uniprotkb/F1N7B6" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 1, "go_terms": [ { "name": "protein stabilization", "id": "GO:0050821", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0050821", "evidence": [ { "database": "UniProtKB", "id": "F1N7B6", "url": "https://www.uniprot.org/uniprotkb/F1N7B6" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [ { "pdb_id": "AF-F1N7B6-F1", "pdb_chain": "global", "start_pos": 1, "end_pos": 114, "overlap": "1.0", "method": "AlphaFold", "type": "alphafold", "resolution": -1.0, "url": "https://data.glygen.org/ln2downloads/pdb/current/AF-F1N7B6-F1.pdb", "url_external": "https://alphafold.ebi.ac.uk/entry/F1N7B6" } ], "lectin_list": [], "domain_list": [], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "homologset.oma", "label": "OMA Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ], "tool_support": { "graph_view": "yes" } }, { "uniprot_canonical_ac": "F1N7E1-1", "uniprot_ac": "F1N7E1", "uniprot_id": "F1N7E1_BOVIN", "mass": { "chemical_mass": 44866.0, "monoisotopic_mass": 44866.0 }, "refseq": { "ac": "XP_010811506", "name": "golgin-45 isoform X1", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_010811506" }, "gene_names": [ { "name": "BLZF1", "type": "recommended", "evidence": [ { "id": "F1N7E1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1N7E1" } ] }, { "name": "BLZF1", "type": "synonym", "evidence": [ { "id": "XP_010811506", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_010811506" } ] } ], "protein_names": [ { "name": "Basic leucine zipper nuclear factor 1", "type": "synonym", "evidence": [ { "id": "F1N7E1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1N7E1/entry#names_and_taxonomy" } ] }, { "name": "golgin-45 isoform X1", "type": "synonym", "evidence": [ { "id": "XP_010811506", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_010811506" } ] } ], "function": [], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Bos taurus", "taxid": 9913, "evidence": [ { "database": "UniProtKB", "id": "F1N7E1", "url": "https://www.uniprot.org/uniprotkb/F1N7E1" } ], "common_name": "Bovine", "glygen_name": "Bovine", "reference_species": "Bos taurus [9913]" } ], "gene": [ { "name": "BLZF1", "url": "https://www.uniprot.org/uniprotkb/F1N7E1", "locus": { "chromosome": "16", "start_pos": 37052628, "end_pos": 37030340, "strand": "-", "evidence": [ { "database": "Ensembl Gene", "id": "ENSBTAG00000002690", "url": "https://www.ensembl.org/id/ENSBTAG00000002690" } ] } } ], "crossref": [ { "id": "F1N7E1", "url": "https://alphafold.ebi.ac.uk/entry/F1N7E1", "database": "AlphaFoldDB", "categories": [] }, { "id": "ENSBTAG00000002690", "url": "https://bgee.org/?page=gene&gene_id=ENSBTAG00000002690", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "504820", "url": "https://www.ncbi.nlm.nih.gov/gene/504820", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR013183", "url": "https://www.ebi.ac.uk/interpro/entry/IPR013183", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR027095", "url": "https://www.ebi.ac.uk/interpro/entry/IPR027095", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "MIDTHKL", "url": "https://omabrowser.org/oma/group/MIDTHKL/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "F1N7E1", "url": "https://www.orthodb.org/?gene=F1N7E1", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR13066", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR13066", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR13066:SF2", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR13066:SF2", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF08227", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF08227", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "XP_010811506", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_010811506", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "F1N7E1", "url": "https://www.uniprot.org/uniprotkb/F1N7E1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "F1N7E1-1", "url": "https://www.uniprot.org/uniprotkb/F1N7E1-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MTTLESLETKAILTPSPIRGAGDGMETEEPPKSIEVTPGIQPITHHILQSPRKKSVPSESPGVLQLGKILAEKAVEVEAVRILVPKAAITHNIPYKNAKVKSLGHHKGELLGQPEGVREPRKELSEVKNTLEKLKNSERRLLQDKEGLSNQLRVQSEVNRELKKLLVASVGDDLQYHFERVAREKNQLILENEALGRNIAQLSEQLERMSIQCDVWRSKFLASRVMADELTNSRAVLQRQNRDAQSAIQDLLSEREQFRQEMIATQKLLEELLVSLQWGREQTYYPSGQPHSTAELALTNHKLAKAVNSHLLGNVGTNGQKKVPSTVEFCSTPAEKMAETVLRILDPVTCTESSPDNPFSESSPTTLLATKKNIGRFHPYTRYENITFNCCNHCQGELIAL", "length": 401, "header": "tr|F1N7E1-1|F1N7E1_BOVIN Isoform 1 of Basic leucine zipper nuclear factor 1 OS=Bos taurus OX=9913 GN=BLZF1 PE=4 SV=3 CANONICAL=F1N7E1-1" }, "isoforms": [ { "isoform_ac": "F1N7E1-1", "url": "https://www.uniprot.org/uniprotkb/F1N7E1/entry", "sequence": { "sequence": "MTTLESLETKAILTPSPIRGAGDGMETEEPPKSIEVTPGIQPITHHILQSPRKKSVPSESPGVLQLGKILAEKAVEVEAVRILVPKAAITHNIPYKNAKVKSLGHHKGELLGQPEGVREPRKELSEVKNTLEKLKNSERRLLQDKEGLSNQLRVQSEVNRELKKLLVASVGDDLQYHFERVAREKNQLILENEALGRNIAQLSEQLERMSIQCDVWRSKFLASRVMADELTNSRAVLQRQNRDAQSAIQDLLSEREQFRQEMIATQKLLEELLVSLQWGREQTYYPSGQPHSTAELALTNHKLAKAVNSHLLGNVGTNGQKKVPSTVEFCSTPAEKMAETVLRILDPVTCTESSPDNPFSESSPTTLLATKKNIGRFHPYTRYENITFNCCNHCQGELIAL", "length": 401, "header": "tr|F1N7E1-1|F1N7E1_BOVIN Isoform 1 of Basic leucine zipper nuclear factor 1 OS=Bos taurus OX=9913 GN=BLZF1 PE=4 SV=3 CANONICAL=F1N7E1-1" }, "locus": { "chromosome": "16", "start_pos": 37052443, "end_pos": 37031341, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000003484.7", "url": "https://www.ensembl.org/id/ENSBTAT00000003484.7" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000003484.5", "url": "https://www.ensembl.org/id/ENSBTAP00000003484.5" } ] } } ], "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "other", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 37, "start_aa": "Thr", "end_pos": 37, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr37", "evidence": [ { "id": "", "database": "GlyGen", "url": "https://data.glygen.org/" } ], "filter_code": "000000000000000010000.00000000001000.0.01000" } ], "phosphorylation": [], "glycation": [], "keywords": [ "glycoprotein", "glycoprotein_predicted" ], "publication": [], "pathway": [], "orthologs": [ { "uniprot_canonical_ac": "B8JM41-1", "protein_name": "Golgin-45", "gene_name": "blzf1", "tax_id": 7955, "organism": "Danio rerio", "sequence": { "sequence": "MMSAELIIKDVSVVAVRGPGDGMETDKPLPAPEQLTEAPLQKICSPKHSPRVATGSPGVLHLGKVSRDACLELEAVRIVVPRAAIIRTGRSGAHTDDRGSPQHGDEPPPAPPSPPPPAEPLQEYKNSLEKLQSSERRLLQDKEGLSNQLRVQTEVNRELKKLLVASVGDDLQYHFERLAREKNHLILENETLCRNLSHTAEQLERMSIQCDVWRSKFLASRVMAEELTNARSALQRQTRDAQCAIQDLLSEREEFSRDMTHTHRCLEQLLVSLQWGRQQTYYPSAKPLSTGELATANHKLADAINAHLLGKLENSGGKKSPSTEICNTPAEKMAEKVLRSLDPVCVSEQEHDASSSDSPFLPNRKSIGRFHPYTRYENITFNCCERCHGEIIVL", "length": 394 }, "evidence": [ { "id": "F1N7E1", "url": "https://omabrowser.org/oma/group/F1N7E1/", "database": "OMA" } ], "glygen_name": "Zebrafish", "common_name": "Zebrafish" }, { "uniprot_canonical_ac": "E1C3Q8-1", "protein_name": "Basic leucine zipper nuclear factor 1", "gene_name": "BLZF1", "tax_id": 9031, "organism": "Gallus gallus", "sequence": { "sequence": "MTSLEKVDYASSPIRGPGDGMETEQMGESLEVSAGASATNHQVRHSPQKKAVSSLSPGVLQLGQIHADKSVEVEAVRILVPKAAITHVVATKNAKVAKSAGHKGDAFHQSDGTADPKKEQTELKNAIEKLKNSEKRLLQDKEGLSNQLRIQTEVNRELKKLLVASVGDDLQYHFERMAREKNQLILENEVLGRNLSQLSEQLERMSIQCDVWRSKFLASRVMADELTNTRAILQRQTRDAQTAIQDLLNERDQFRQEMIHTQKLLEELMVSLQWGRQQTYYPSAQPYTTTELASVNCKLAKAVSSHLLGNVGTSSPKKTSTAVEFCNTPAEKMAERVLRVLDPAARTETSTEASFSETSPSSFLSTKKNIGRFHPYTRYEDITFNCCDHCQGELIAL", "length": 397 }, "evidence": [ { "id": "F1N7E1", "url": "https://omabrowser.org/oma/group/F1N7E1/", "database": "OMA" } ], "glygen_name": "Chicken", "common_name": "Chicken" }, { "uniprot_canonical_ac": "I3LIF5-1", "protein_name": "Basic leucine zipper nuclear factor 1", "gene_name": "BLZF1", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MTTLEGLETKALLTSAPIRGAGDGMETEEPPKTVEVTSGIQPIKHHILQSPRKKAVPSESPGVLQLGKIIAEKAVEVEAIRILVPKAAISHDIPNKNAKAKSLGHHKGEILGQPEGIVEPRKEVSEVKTVLEKLKNSERRLLQDKEGLSNQLRVQSEVNRELKKLLVASVGDDLQYHFERLAREKNQLILENEALGRNVAQLSEQLERMSIQCDVWRSKFLASRVMADELTNSRAVLQRQNRDAQSAIQDLLSEREQFRQEMIATQKLLEELLVSLQWGREQTYYPSAQPHSTAELALTNHKLAKAVNSHLLGNVGTNGQKRIPSTIEFCSTPAEKMAETVLRILDPITCTENSPGNPFSESSPTTLLATKKNIGRFHPYTRYENVTFNCCNHCQGELIAL", "length": 401 }, "evidence": [ { "id": "F1N7E1", "url": "https://omabrowser.org/oma/group/F1N7E1/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "Q6AYB8-1", "protein_name": "Golgin-45", "gene_name": "Blzf1", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MEKMTTLKSFESKGILTSTPIRGAGDGMETEEPPKSVEVTHGVQPINQHVLPSPRKKVPSDSPGVLQLGKILNEKTVEVEAVRIFVPKAAITHDIPTKSAKVKSLGHHREELHNQSEVVTDPRKELSEVKKVLEKLKNSERRLLQDKEGLSNQLRVQTEVNRELKKLLVASVGDDPQYHFERLAREKNQLILENEALGRNTAQLSEQLERMSIQCDVWRSKFLASRVMADELTNFRVVLQHQNRDAQSAIQDLLSEREQFRQEMISTQKFLEELLVSLQWGREQTYSPNTQPHSTADLALTNHRLAEAVHAHLLGNVGISHPKRTPATAEVCSTPAEKMAEKVLRILDPVACTESSPDNAFAESTLLTTKKNIGRFHPYTRYENITFNCCSHCQGELLAL", "length": 400 }, "evidence": [ { "id": "F1N7E1", "url": "https://omabrowser.org/oma/group/F1N7E1/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "Q8R2X8-1", "protein_name": "Golgin-45", "gene_name": "Blzf1", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MEKMTTLKSSENKGILTSTPIRGAGDGMETEEPPKSVEVTHGVQPINQHVLPSPRKKVSSDSPGVLQLGKILNERTVEVEAVRIFVPKAAITHDIPTKNTKVKSLGHHREELHNQAEVVTDPRKELSEVKKVLEKLKNSERRLLQDKEGLSNQLRVQTEINRELKKLLVASVGDDPQYHFERLAREKNQLILENEALGRNTAQLSEQLERMSIQCDVWRSKFLASRVMADELTNFRVVLQRQNRDAQSAIQDLLSEREQFRQEMTSTQKFLEELLVSLQWGREQTYSPNTQPHSTADLALTNHGLAQAIHAHLLGNVGISHQKKIPTTVEFCSTPAEKMAEKVLRILDPVACTESSPDNQFAESSPTTLLTTKKNIGRFHPYTRYENITFNCCNHCQGELIAL", "length": 403 }, "evidence": [ { "id": "F1N7E1", "url": "https://omabrowser.org/oma/group/F1N7E1/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q9H2G9-1", "protein_name": "Golgin-45", "gene_name": "BLZF1", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MTTKNLETKVTVTSSPIRGAGDGMETEEPPKSVEVTSGVQSRKHHSLQSPWKKAVPSESPGVLQLGKMLTEKAMEVKAVRILVPKAAITHDIPNKNTKVKSLGHHKGEFLGQSEGVIEPNKELSEVKNVLEKLKNSERRLLQDKEGLSNQLRVQTEVNRELKKLLVASVGDDLQYHFERLAREKNQLILENEALGRNTAQLSEQLERMSIQCDVWRSKFLASRVMADELTNSRAALQRQNRDAHGAIQDLLSEREQFRQEMIATQKLLEELLVSLQWGREQTYSPSVQPHSTAELALTNHKLAKAVNSHLLGNVGINNQKKIPSTVEFCSTPAEKMAETVLRILDPVTCKESSPDNPFFESSPTTLLATKKNIGRFHPYTRYENITFNCCNHCRGELIAL", "length": 400 }, "evidence": [ { "id": "F1N7E1", "url": "https://omabrowser.org/oma/group/F1N7E1/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" } ], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 2, "go_terms": [ { "name": "nucleoplasm", "id": "GO:0005654", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005654", "evidence": [ { "database": "UniProtKB", "id": "F1N7E1", "url": "https://www.uniprot.org/uniprotkb/F1N7E1" } ], "pmid": "" }, { "name": "Golgi apparatus", "id": "GO:0005794", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005794", "evidence": [ { "database": "UniProtKB", "id": "F1N7E1", "url": "https://www.uniprot.org/uniprotkb/F1N7E1" } ], "pmid": "" } ] }, { "name": "Molecular Function", "total": 1, "go_terms": [ { "name": "ubiquitin protein ligase binding", "id": "GO:0031625", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0031625", "evidence": [ { "database": "UniProtKB", "id": "F1N7E1", "url": "https://www.uniprot.org/uniprotkb/F1N7E1" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 2, "go_terms": [ { "name": "Golgi to plasma membrane protein transport", "id": "GO:0043001", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0043001", "evidence": [ { "database": "UniProtKB", "id": "F1N7E1", "url": "https://www.uniprot.org/uniprotkb/F1N7E1" } ], "pmid": "" }, { "name": "Golgi organization", "id": "GO:0007030", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007030", "evidence": [ { "database": "UniProtKB", "id": "F1N7E1", "url": "https://www.uniprot.org/uniprotkb/F1N7E1" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 385, "end_pos": 387, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [ { "pdb_id": "AF-F1N7E1-F1", "pdb_chain": "global", "start_pos": 1, "end_pos": 401, "overlap": "1.0", "method": "AlphaFold", "type": "alphafold", "resolution": -1.0, "url": "https://data.glygen.org/ln2downloads/pdb/current/AF-F1N7E1-F1.pdb", "url_external": "https://alphafold.ebi.ac.uk/entry/F1N7E1" } ], "lectin_list": [], "domain_list": [], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "homologset.oma", "label": "OMA Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [ 37 ], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 385, "end_pos": 387 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 1 }, { "field": "total_sites", "count": 1 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 1 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "exact_sites", "count": 1 }, { "field": "exact_o_linked_sites", "count": 1 }, { "field": "fuzzy_sites", "count": 0 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_pos", "start_aa", "end_pos", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 1 }, { "field": "total_sites", "count": 1 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 1 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "exact_sites", "count": 1 }, { "field": "exact_o_linked_sites", "count": 1 }, { "field": "fuzzy_sites", "count": 0 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_pos", "start_aa", "end_pos", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ], "tool_support": { "graph_view": "yes" } }, { "uniprot_canonical_ac": "F1N7F5-1", "uniprot_ac": "F1N7F5", "uniprot_id": "F1N7F5_BOVIN", "mass": { "chemical_mass": 34044.0, "monoisotopic_mass": 34044.0 }, "refseq": { "ac": "XP_005224679", "name": "serine protease 27", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_005224679" }, "gene_names": [ { "name": "PRSS27", "type": "recommended", "evidence": [ { "id": "F1N7F5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1N7F5" } ] }, { "name": "PRSS27", "type": "synonym", "evidence": [ { "id": "XP_005224679", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_005224679" } ] } ], "protein_names": [ { "name": "tryptase", "type": "recommended", "evidence": [ { "id": "F1N7F5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1N7F5/entry#names_and_taxonomy" } ] }, { "name": "3.4.21.59", "type": "synonym", "evidence": [ { "id": "F1N7F5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1N7F5/entry#names_and_taxonomy" } ] }, { "name": "serine protease 27", "type": "synonym", "evidence": [ { "id": "XP_005224679", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_005224679" } ] } ], "function": [ { "annotation": "Tryptase is the major neutral protease present in mast cells and is secreted upon the coupled activation-degranulation response of this cell type.", "evidence": [ { "database": "UniProtKB", "id": "F1N7F5", "url": "https://www.uniprot.org/uniprotkb/F1N7F5#function" }, { "database": "UniProtKB", "id": "ARBA00054350", "url": "https://www.uniprot.org/uniprotkb/ARBA00054350#function" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Bos taurus", "taxid": 9913, "evidence": [ { "database": "UniProtKB", "id": "F1N7F5", "url": "https://www.uniprot.org/uniprotkb/F1N7F5" } ], "common_name": "Bovine", "glygen_name": "Bovine", "reference_species": "Bos taurus [9913]" } ], "gene": [ { "name": "PRSS27", "url": "https://www.uniprot.org/uniprotkb/F1N7F5", "locus": { "chromosome": "25", "start_pos": 2125112, "end_pos": 2133910, "strand": "+", "evidence": [ { "database": "Ensembl Gene", "id": "ENSBTAG00000040394", "url": "https://www.ensembl.org/id/ENSBTAG00000040394" } ] } } ], "crossref": [ { "id": "F1N7F5", "url": "https://alphafold.ebi.ac.uk/entry/F1N7F5", "database": "AlphaFoldDB", "categories": [] }, { "id": "ENSBTAG00000040394", "url": "https://bgee.org/?page=gene&gene_id=ENSBTAG00000040394", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "cd00190", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd00190", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "521465", "url": "https://www.ncbi.nlm.nih.gov/gene/521465", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR001254", "url": "https://www.ebi.ac.uk/interpro/entry/IPR001254", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR001314", "url": "https://www.ebi.ac.uk/interpro/entry/IPR001314", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR009003", "url": "https://www.ebi.ac.uk/interpro/entry/IPR009003", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR018114", "url": "https://www.ebi.ac.uk/interpro/entry/IPR018114", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR033116", "url": "https://www.ebi.ac.uk/interpro/entry/IPR033116", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR043504", "url": "https://www.ebi.ac.uk/interpro/entry/IPR043504", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "bta:521465", "url": "https://www.genome.jp/dbget-bin/www_bget?bta:521465", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "PVCMPDP", "url": "https://omabrowser.org/oma/group/PVCMPDP/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "F1N7F5", "url": "https://www.orthodb.org/?gene=F1N7F5", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR24253", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR24253", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR24253:SF119", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR24253:SF119", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00089", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00089", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "XP_005224679", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_005224679", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "F1N7F5", "url": "https://www.uniprot.org/uniprotkb/F1N7F5", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "F1N7F5-1", "url": "https://www.uniprot.org/uniprotkb/F1N7F5-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MRQVLAAVLLLLLLRSGTRGGEALNACGRPRMLNRMVGGQNALEGEWPWQVSIQRNGSHFCGGSLITDRWVLTAAHCFSNTSETSLYQVLLGVLQLARPGPHAVYARVKRVESNPKYQGMASSADVALVELEAPVTFTNYILPVCVPDPSVVFESGMKCWVTGWGTPSEQDSLPKPRTLQKLAVPIISTPKCNLLYSKDAESGFQPRTIKDDMLCAGFAEGKRDACKGDSGGPLVCLVGQVWLQAGVISWGEGCARRNRPGVYIRLTSHHDWIHRIIPELQFQRAGPGSAQKRDPRTRQPLGRNSARYPAA", "length": 311, "header": "tr|F1N7F5-1|F1N7F5_BOVIN Isoform 1 of tryptase OS=Bos taurus OX=9913 GN=PRSS27 PE=4 SV=3 CANONICAL=F1N7F5-1" }, "isoforms": [ { "isoform_ac": "F1N7F5-1", "url": "https://www.uniprot.org/uniprotkb/F1N7F5/entry", "sequence": { "sequence": "MRQVLAAVLLLLLLRSGTRGGEALNACGRPRMLNRMVGGQNALEGEWPWQVSIQRNGSHFCGGSLITDRWVLTAAHCFSNTSETSLYQVLLGVLQLARPGPHAVYARVKRVESNPKYQGMASSADVALVELEAPVTFTNYILPVCVPDPSVVFESGMKCWVTGWGTPSEQDSLPKPRTLQKLAVPIISTPKCNLLYSKDAESGFQPRTIKDDMLCAGFAEGKRDACKGDSGGPLVCLVGQVWLQAGVISWGEGCARRNRPGVYIRLTSHHDWIHRIIPELQFQRAGPGSAQKRDPRTRQPLGRNSARYPAA", "length": 311, "header": "tr|F1N7F5-1|F1N7F5_BOVIN Isoform 1 of tryptase OS=Bos taurus OX=9913 GN=PRSS27 PE=4 SV=3 CANONICAL=F1N7F5-1" }, "locus": { "chromosome": "25", "start_pos": 2132837, "end_pos": 2126025, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000027417.7", "url": "https://www.ensembl.org/id/ENSBTAT00000027417.7" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000027417.6", "url": "https://www.ensembl.org/id/ENSBTAP00000027417.6" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [ "enzyme" ], "publication": [], "pathway": [ { "id": "bta:521465", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?bta:521465", "resource": "KEGG Pathway" } ], "orthologs": [ { "uniprot_canonical_ac": "G3I2U1-1", "protein_name": "Serine protease 27 isoform X1", "gene_name": "Prss27", "tax_id": 10029, "organism": "Cricetulus griseus", "sequence": { "sequence": "MRQSHIPALLLLPLLLRSGTDGASTLRACGHPRMFNRMVGGEDALEGEWPWQVSIQRNGTHFCGGSLIAPTWVLTAAHCFSNTSDISIYQVLLGALQLQQPGPHALYVRVKRVESNPQYQGMASSADVALVELQVPVTFTNYILPVCLPDPSIIFESGMNCWVTGWGSPSEQDRLPNPRILQKLAVPIIDTPRCNLLYSRDADSDFQLKTIKDDMLCAGFAEGKKDACKGDSGGPLVCLVDQSWVQAGVISWGEGCARRNRPGVYIRVTSHHKWIHQIIPELKFQGKANSQQQQRDPRGWQHLGNSAPCLVAHAVMLVLVTLLTIL", "length": 326 }, "evidence": [ { "id": "F1N7F5", "url": "https://omabrowser.org/oma/group/F1N7F5/", "database": "OMA" } ], "glygen_name": "Hamster", "common_name": "Chinese hamster" }, { "uniprot_canonical_ac": "Q6BEA2-1", "protein_name": "Serine protease 27", "gene_name": "Prss27", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MRQPHITALLLLPLLLRSGTEGAEAMRACGHPRMFNRMVGGEDALEGEWPWQVSIQRNGAHFCGGSLIAPTWVLTAAHCFSNTSDISIYQVLLGALKLQQPGPHALYVPVKRVKSHPEYQGMASSADVALVELQVPVTFTKYILPVCLPDPSVVFKSGMNCWVTGWGSPSEQDRLPNPRILQKLAVPLIDTPKCNLLYSKDAEADIQLKTIKDDMLCAGFAEGKKDACKGDSGGPLVCLVDQSWVQAGVISWGEGCARRNRPGVYIRVASHYQWIHQIIPELQFQGRAGSQQQQRDPRGWQPLAENSAPCLAAHAVLLALGALMLGIL", "length": 328 }, "evidence": [ { "id": "F1N7F5", "url": "https://omabrowser.org/oma/group/F1N7F5/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "Q8BJR6-1", "protein_name": "Serine protease 27", "gene_name": "Prss27", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MRQPHIAALLLLPLLLRSGTEGARTLRACGHPKMFNRMVGGENALEGEWPWQVSIQRNGIHFCGGSLIAPTWVLTAAHCFSNTSDISIYQVLLGALKLQQPGPHALYVPVKQVKSNPQYQGMASSADVALVELQGPVTFTNYILPVCLPDPSVIFESGMNCWVTGWGSPSEQDRLPNPRVLQKLAVPIIDTPKCNLLYNKDVESDFQLKTIKDDMLCAGFAEGKKDACKGDSGGPLVCLVDQSWVQAGVISWGEGCARRNRPGVYIRVTSHHKWIHQIIPELQFQGRAGTQQQQKDSQGQQRLAGNSAPCLAAHAMVLALGALLLRIV", "length": 328 }, "evidence": [ { "id": "F1N7F5", "url": "https://omabrowser.org/oma/group/F1N7F5/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q9BQR3-1", "protein_name": "Serine protease 27", "gene_name": "PRSS27", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MRRPAAVPLLLLLCFGSQRAKAATACGRPRMLNRMVGGQDTQEGEWPWQVSIQRNGSHFCGGSLIAEQWVLTAAHCFRNTSETSLYQVLLGARQLVQPGPHAMYARVRQVESNPLYQGTASSADVALVELEAPVPFTNYILPVCLPDPSVIFETGMNCWVTGWGSPSEEDLLPEPRILQKLAVPIIDTPKCNLLYSKDTEFGYQPKTIKNDMLCAGFEEGKKDACKGDSGGPLVCLVGQSWLQAGVISWGEGCARQNRPGVYIRVTAHHNWIHRIIPKLQFQPARLGGQK", "length": 290 }, "evidence": [ { 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"http://www.pantherdb.org/panther/family.do?clsAccession=PTHR46105", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR46105:SF13", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR46105:SF13", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00651", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00651", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "NP_001178391", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001178391", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "F1N7I1", "url": "https://www.uniprot.org/uniprotkb/F1N7I1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "F1N7I1-1", "url": "https://www.uniprot.org/uniprotkb/F1N7I1-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MDTSTPLPPVAPSPACNPAPRTIQIEFPQHSSLLLEALNRHRLEGKFCDVSLLVQGRELRAHKAVLAAASPYFHDKLLLGDAPRLTLPNVIEADAFEGLLQLIYSGHLRLPLDALPAHLLVASGLQMWQVVDQCSEILRELENTGGGISSRGATPFHTLLSTTGGWCIRSSPFQTPAQSSPSTQSPIGGEGSELGDVLQLQVEEEEEEDEEDQGSAAPSQTPQPQRESGSFPRPPVSHPLPTSTTPCRLPEGESAPPEPPAPHTALPPKVFYIKQEPFESKEEIAGGGSQSVGAKEETKVFPAGNTEENGELGFLLPSGAGTTSGGGGPSWKPVDLHGNEILSGGGGPGGAGQAVHGPVKLGGAPPADGKRFGCLCGKRFAVKPKRDRHIMLTFSLRPFGCGICNKRFKLKHHLTEHMKTHAGALHACPHCGRRFRVHACFLRHRDLCKGQGWATAHWTYK", "length": 461, "header": "tr|F1N7I1-1|F1N7I1_BOVIN Isoform 1 of Zinc finger and BTB domain containing 9 OS=Bos taurus OX=9913 GN=ZBTB9 PE=4 SV=2 CANONICAL=F1N7I1-1" }, "isoforms": [ { "isoform_ac": "F1N7I1-1", "url": "https://www.uniprot.org/uniprotkb/F1N7I1/entry", "sequence": { "sequence": "MDTSTPLPPVAPSPACNPAPRTIQIEFPQHSSLLLEALNRHRLEGKFCDVSLLVQGRELRAHKAVLAAASPYFHDKLLLGDAPRLTLPNVIEADAFEGLLQLIYSGHLRLPLDALPAHLLVASGLQMWQVVDQCSEILRELENTGGGISSRGATPFHTLLSTTGGWCIRSSPFQTPAQSSPSTQSPIGGEGSELGDVLQLQVEEEEEEDEEDQGSAAPSQTPQPQRESGSFPRPPVSHPLPTSTTPCRLPEGESAPPEPPAPHTALPPKVFYIKQEPFESKEEIAGGGSQSVGAKEETKVFPAGNTEENGELGFLLPSGAGTTSGGGGPSWKPVDLHGNEILSGGGGPGGAGQAVHGPVKLGGAPPADGKRFGCLCGKRFAVKPKRDRHIMLTFSLRPFGCGICNKRFKLKHHLTEHMKTHAGALHACPHCGRRFRVHACFLRHRDLCKGQGWATAHWTYK", "length": 461, "header": "tr|F1N7I1-1|F1N7I1_BOVIN Isoform 1 of Zinc finger and BTB domain containing 9 OS=Bos taurus OX=9913 GN=ZBTB9 PE=4 SV=2 CANONICAL=F1N7I1-1" }, "locus": { "chromosome": "23", "start_pos": 7628296, "end_pos": 7626914, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000054216.4", "url": "https://www.ensembl.org/id/ENSBTAT00000054216.4" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000048532.2", "url": "https://www.ensembl.org/id/ENSBTAP00000048532.2" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [ { "id": "bta:539371", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?bta:539371", "resource": "KEGG Pathway" } ], "orthologs": [ { "uniprot_canonical_ac": "Q6MGD2-1", "protein_name": "Zinc finger and BTB domain containing 9", "gene_name": "Zbtb9", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MDASTPLPPAPSSPRCNPAPQTIHIDFPHHSSSLLESLNRHRLEGKFCDVSLLVQGRELRAHKAVLAAASPYFHDKLLLGDAPRLTLPNVIEADAFEGLLQLIYSGSLHLPLDALPAHLLVASGLQMWQVVDRCSEILRELETSSGISSGGGASSLTLLSTTSAGGWCIRSSPFQNPGRSSASTENSAAPESPSGGEGGELEGMLQIQVKVEEEEEQRSAAPPFQTPQPERVSGAVSQACGSHPLPTSTLPSKPSEDENSTLDPPAPPVQTSQILYVNQENVECKEETSGGRTLSGGAKEKTKVLPGENSEENGELRYLLSSGGGETSGAGDPSWKPVDLHGNEILSGGGGPGGTGQAMHGPVKLGGTPPADGKCFACLCGKRFAVKPKRDRHIMLTFSLRPFGCGICNKRFKLKHHLTEHMKTHARALHACPHCGRRFRVQAFFLRHRDLCKGQGWPTYHWTYK", "length": 465 }, "evidence": [ { "id": "F1N7I1", "url": "https://omabrowser.org/oma/group/F1N7I1/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "Q8CDC7-1", "protein_name": "Zinc finger and BTB domain-containing protein 9", "gene_name": "Zbtb9", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MDASTPLPPASSSPRCNPAPQTIHIEFPHHSSSLLESLNRHRLEGKFCDVSLLVQGRELRAHKAVLAAASPYFHDKLLLGDAPRLTLPNVIEADAFEGLLQLIYSGSLHLPLDALPAHLLVASGLQMWQVVDRCSEILRELETSGGISAGGRASSLTLISTTSSGGWCIRSSPFQNPVRSSASTENSVLPESPAGGEGSELEGMLQIQVKVEEEEEQGSAAPLFQTPQPERVSGGVSQACGSHPLPTPALPSKPSEDESSTVDPPAPPVQASQILYVNQENVECKEEIARGTKEKTKVLSGEDSEEKEELRYLLSSGGGESSGAGDPSWKPVDLHGNEILSGDGGPGGTGQAMHGPVKLGGTPPADGKCFACLCGKRFAVKPKRDRHIMLTFSLRPFGCGICNKRFKLKHHLTEHMKTHARALHACPHCGRRFRVQAFFLRHRDLCKGQGWPTYHWTYK", "length": 459 }, "evidence": [ { "id": "F1N7I1", "url": "https://omabrowser.org/oma/group/F1N7I1/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q96C00-1", "protein_name": "Zinc finger and BTB domain-containing protein 9", "gene_name": "ZBTB9", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "METPTPLPPVPASPTCNPAPRTIQIEFPQHSSSLLESLNRHRLEGKFCDVSLLVQGRELRAHKAVLAAASPYFHDKLLLGDAPRLTLPSVIEADAFEGLLQLIYSGRLRLPLDALPAHLLVASGLQMWQVVDQCSEILRELETSGGGISARGGNSYHALLSTTSSTGGWCIRSSPFQTPVQSSASTESPASTESPVGGEGSELGEVLQIQVEEEEEEEEDDDDEDQGSATLSQTPQPQRVSGVFPRPHGPHPLPMTATPRKLPEGESAPLELPAPPALPPKIFYIKQEPFEPKEEISGSGTQPGGAKEETKVFSGGDTEGNGELGFLLPSGPGPTSGGGGPSWKPVDLHGNEILSGGGGPGGAGQAVHGPVKLGGTPPADGKRFGCLCGKRFAVKPKRDRHIMLTFSLRPFGCGICNKRFKLKHHLTEHMKTHAGALHACPHCGRRFRVHACFLRHRDLCKGQGWATAHWTYK", "length": 473 }, "evidence": [ { "id": "F1N7I1", "url": "https://omabrowser.org/oma/group/F1N7I1/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" } ], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 1, "go_terms": [ { "name": "nucleus", "id": "GO:0005634", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005634", "evidence": [ { "database": "UniProtKB", "id": "F1N7I1", "url": "https://www.uniprot.org/uniprotkb/F1N7I1" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 1, "go_terms": [ { "name": "regulation of transcription by RNA polymerase II", "id": "GO:0006357", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006357", "evidence": [ { "database": "UniProtKB", "id": "F1N7I1", "url": "https://www.uniprot.org/uniprotkb/F1N7I1" } ], "pmid": "" } ] }, { "name": "Molecular Function", "total": 4, "go_terms": [ { "name": "zinc ion binding", "id": "GO:0008270", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008270", "evidence": [ { "database": "UniProtKB", "id": "F1N7I1", "url": "https://www.uniprot.org/uniprotkb/F1N7I1" } ], "pmid": "" }, { "name": "identical protein binding", "id": "GO:0042802", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0042802", "evidence": [ { "database": "UniProtKB", "id": "F1N7I1", "url": "https://www.uniprot.org/uniprotkb/F1N7I1" } ], "pmid": "" }, { "name": "RNA polymerase II cis-regulatory region sequence-specific DNA binding", "id": "GO:0000978", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000978", "evidence": [ { "database": "UniProtKB", "id": "F1N7I1", "url": "https://www.uniprot.org/uniprotkb/F1N7I1" } ], "pmid": "" }, { "name": "DNA-binding transcription factor activity, RNA polymerase II-specific", "id": "GO:0000981", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000981", "evidence": [ { "database": "UniProtKB", "id": "F1N7I1", "url": "https://www.uniprot.org/uniprotkb/F1N7I1" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [ { "pdb_id": "AF-F1N7I1-F1", "pdb_chain": "global", "start_pos": 1, "end_pos": 461, "overlap": "1.0", "method": "AlphaFold", "type": "alphafold", "resolution": -1.0, "url": "https://data.glygen.org/ln2downloads/pdb/current/AF-F1N7I1-F1.pdb", "url_external": "https://alphafold.ebi.ac.uk/entry/F1N7I1" } ], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "F1N7I1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1N7I1" }, { "id": "PS50097", "database": "PROSITE", "url": "https://prosite.expasy.org/PS50097" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "BTB", "eco_id": "ECO_0000259", "start_pos": 48, "end_pos": 112, "start_aa": "Cys", "end_aa": "Leu", "glycosite_overlap": [] }, { "evidence": [ { "id": "F1N7I1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1N7I1" }, { "id": "PS50157", "database": "PROSITE", "url": "https://prosite.expasy.org/PS50157" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "C2H2-type", "eco_id": "ECO_0000259", "start_pos": 399, "end_pos": 426, "start_aa": "Phe", "end_aa": "His", "glycosite_overlap": [] } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "homologset.oma", "label": "OMA Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": 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"n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ], "tool_support": { "graph_view": "yes" } }, { "uniprot_canonical_ac": "F1N7I6-1", "uniprot_ac": "F1N7I6", "uniprot_id": "F1N7I6_BOVIN", "mass": { "chemical_mass": 22290.0, "monoisotopic_mass": 22290.0 }, "refseq": { "ac": "XP_015331044", "name": "grancalcin", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_015331044" }, "gene_names": [ { "name": "GCA", "type": "recommended", "evidence": [ { "id": "F1N7I6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1N7I6" } ] }, { "name": "GCA", "type": "synonym", "evidence": [ { "id": "XP_015331044", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_015331044" } ] } ], "protein_names": [ { "name": "Grancalcin", "type": "synonym", "evidence": [ { "id": "F1N7I6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1N7I6/entry#names_and_taxonomy" } ] }, { "name": "grancalcin", "type": "synonym", "evidence": [ { "id": "XP_015331044", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_015331044" } ] } ], "function": [], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Bos taurus", "taxid": 9913, "evidence": [ { "database": "UniProtKB", "id": "F1N7I6", "url": "https://www.uniprot.org/uniprotkb/F1N7I6" } ], "common_name": "Bovine", "glygen_name": "Bovine", "reference_species": "Bos taurus [9913]" } ], "gene": [ { "name": "GCA", "url": "https://www.uniprot.org/uniprotkb/F1N7I6", "locus": { "chromosome": "2", "start_pos": 34068877, "end_pos": 34087578, "strand": "+", "evidence": [ { "database": "Ensembl Gene", "id": "ENSBTAG00000018446", "url": "https://www.ensembl.org/id/ENSBTAG00000018446" } ] } } ], "crossref": [ { "id": "F1N7I6", "url": "https://alphafold.ebi.ac.uk/entry/F1N7I6", "database": "AlphaFoldDB", "categories": [] }, { "id": "ENSBTAG00000018446", "url": "https://bgee.org/?page=gene&gene_id=ENSBTAG00000018446", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "507139", "url": "https://www.ncbi.nlm.nih.gov/gene/507139", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR002048", "url": "https://www.ebi.ac.uk/interpro/entry/IPR002048", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR011992", "url": "https://www.ebi.ac.uk/interpro/entry/IPR011992", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR018247", "url": "https://www.ebi.ac.uk/interpro/entry/IPR018247", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "bta:507139", "url": "https://www.genome.jp/dbget-bin/www_bget?bta:507139", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "NGAYSPF", "url": "https://omabrowser.org/oma/group/NGAYSPF/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "F1N7I6", "url": "https://www.orthodb.org/?gene=F1N7I6", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR46735", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR46735", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR46735:SF5", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR46735:SF5", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF13833", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF13833", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "R-BTA-6798695", "url": "https://www.reactome.org/PathwayBrowser/#R-BTA-6798695", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "XP_015331044", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_015331044", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "F1N7I6", "url": "https://www.uniprot.org/uniprotkb/F1N7I6", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "F1N7I6-1", "url": "https://www.uniprot.org/uniprotkb/F1N7I6-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MAYPGYGGGFGNFGNPLGQPGYPGHPAYPGSISTGDPMWKCFLAIAGQDGEVDAEELQKCLTQSGISGTYSPFSLETCRIMIAMLDRDYSGKMGFNEFKELWAALNSWKQNFITVDKDGSGSVEHHELNQAIAAMGYRLSPQTVTTIVKRYSKNGRIFFDDYVACCVKLRALTDFFRRRDHLQQGVVSFVYDDFLQGTMAV", "length": 201, "header": "tr|F1N7I6-1|F1N7I6_BOVIN Isoform 1 of Grancalcin OS=Bos taurus OX=9913 GN=GCA PE=4 SV=2 CANONICAL=F1N7I6-1" }, "isoforms": [ { "isoform_ac": "F1N7I6-1", "url": "https://www.uniprot.org/uniprotkb/F1N7I6/entry", "sequence": { "sequence": "MAYPGYGGGFGNFGNPLGQPGYPGHPAYPGSISTGDPMWKCFLAIAGQDGEVDAEELQKCLTQSGISGTYSPFSLETCRIMIAMLDRDYSGKMGFNEFKELWAALNSWKQNFITVDKDGSGSVEHHELNQAIAAMGYRLSPQTVTTIVKRYSKNGRIFFDDYVACCVKLRALTDFFRRRDHLQQGVVSFVYDDFLQGTMAV", "length": 201, "header": "tr|F1N7I6-1|F1N7I6_BOVIN Isoform 1 of Grancalcin OS=Bos taurus OX=9913 GN=GCA PE=4 SV=2 CANONICAL=F1N7I6-1" }, "locus": { "chromosome": "2", "start_pos": 34087468, "end_pos": 34070356, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000024550.7", "url": "https://www.ensembl.org/id/ENSBTAT00000024550.7" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000024550.5", "url": "https://www.ensembl.org/id/ENSBTAP00000024550.5" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [ { "id": "bta:507139", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?bta:507139", "resource": "KEGG Pathway" }, { "id": "R-BTA-6798695", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-BTA-6798695", "resource": "Reactome", "description": "Neutrophil degranulation" } ], "orthologs": [ { "uniprot_canonical_ac": "A0A4X1VHX8-1", "protein_name": "Grancalcin", "gene_name": "GCA", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MKRSRIVRCKRKDVCTQKTYNTLQRPLLIFPLRENFICLDSWPNVKHTVKVVKRNRNLGLAERTPTLWVTRDTGGIVMAYPGYGGGFGNFSNPMPGMHMHVGQPVPGAGPAVPPSGCPAYPPYSDSYPPAGDPMWTYFTAVAGQDGEVDAEELQKCLTQSGISGTYSPFSLETCRIMIAMLDRDCTGKMGFNEFKELLAVINAWKQNFINIDHDRSGTVEHHELNQAIAAMGYRLSPQTLTAIVKRYSKNGRIFFDDYVACCVKLRALTDFFRRRDHLQQGMVNFSYDDFLQGTMTI", "length": 297 }, "evidence": [ { "id": "F1N7I6", "url": "https://omabrowser.org/oma/group/F1N7I6/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "A0A8C2N6W2-1", "protein_name": "Grancalcin", "gene_name": "Gca", "tax_id": 10029, "organism": "Cricetulus griseus", "sequence": { "sequence": "MAYPGYGGAFGNFSGHIPGMQMQMGQPMPGPSMFSGSYPGYLAYSDSYSPADDSMWTYFTAVAGQDGEVDAEELQRCLTQSGISGTYAPFSLETCRIMIAMLDRDYTGKMGFSEFKELWAALTAWKQNFMTIDQDQSGSVEHHELSQAIALMGYRLSPQTLAAIVKRYSKNGRIFFDDYVACCVKLRALTDFFRRRDHLQQGIVNFMYEDFLQGTMTI", "length": 218 }, "evidence": [ { "id": "F1N7I6", "url": "https://omabrowser.org/oma/group/F1N7I6/", "database": "OMA" } ], "glygen_name": "Hamster", "common_name": "Chinese hamster" }, { "uniprot_canonical_ac": "D3ZYI0-1", "protein_name": "Grancalcin", "gene_name": "Gca", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MAYPGYGGAFGNFGGQIPGMQVQMGQPVPGAGPNMFSGGYPGYLTYSDSYSPADDSMWTYFTAVAGQDGEVDAEELQRCLTQSGISGSYAPFSLETCRIMIAMLDRDYTGKMGFNEFKELWAALNAWKQNFMSIDQDQSGTVEHHELSQAIALMGYRLSPQTLAAIVRRYSKNGRIFFDDYVACCVKLRALTDFFRRRDHLQQGIVNFMYEDPGAAPSEWQQFKEKQVICYCLTVQKFYVELVVWTCVCVCVCVCVCVCVCVYQNPPRRVLIFFSYIFPPPPPPPSLPPPPPPPLPSSSSPFLLFSLPPPLPSSSSPFLLLSLLPLLLPFFYLLLLLMESSIPGEIFCKDFKE", "length": 353 }, "evidence": [ { "id": "F1N7I6", "url": "https://omabrowser.org/oma/group/F1N7I6/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "P28676-1", "protein_name": "Grancalcin", "gene_name": "GCA", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MAYPGYGGGFGNFSIQVPGMQMGQPVPETGPAILLDGYSGPAYSDTYSSAGDSVYTYFSAVAGQDGEVDAEELQRCLTQSGINGTYSPFSLETCRIMIAMLDRDHTGKMGFNAFKELWAALNAWKENFMTVDQDGSGTVEHHELRQAIGLMGYRLSPQTLTTIVKRYSKNGRIFFDDYVACCVKLRALTDFFRKRDHLQQGSANFIYDDFLQGTMAI", "length": 217 }, "evidence": [ { "id": "F1N7I6", "url": "https://omabrowser.org/oma/group/F1N7I6/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "Q8VC88-1", "protein_name": "Grancalcin", "gene_name": "Gca", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MAYPGYGGAFGNFSGQIPGMQMQMGQPMPGAGPNMFSGGYPGYLGYSDSYSPADDSMWTYFTAVAGQDGEVDAEELQRCLTQSGISGTYAPFSLETCRIMIAMLDRDYTGKMGFNEFKELWAALNAWKQNFMTIDQDQSGTVEHHELSQAIALMGYRLSPQTLAAIVRRYSKNGRIFFDDYVACCVKLRALTDFFRRRDHLQQGIVNFMYEDFLQGTMTI", "length": 220 }, "evidence": [ { "id": "F1N7I6", "url": "https://omabrowser.org/oma/group/F1N7I6/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q8W4L0-1", "protein_name": "Probable calcium-binding protein CML49", "gene_name": "CML49", "tax_id": 3702, "organism": "Arabidopsis thaliana", "sequence": { "sequence": "MSGYPPSSQGYGYGGNPPPPQPPYGSTGNNPPPYGSSGSNPPPPYGSSASSPYAVPYGAQPAPYGAPPSAPYASLPGDHNKPHKEKPHGASYGSPSPGGYGAHPSSGPSDYGGYGGAPQQSGHGGGYGGAPQQSGHGGGYGAPPPQASYGSPFASLVPSAFPPGTDPNIVACFQAADRDNSGFIDDKELQGALSSYNQSFSIRTVHLLMYLFTNSNVRKIGPKEFTSLFFSLQNWRSIFERFDKDRSGRIDTNELRDALMSLGFSVSPVILDLLVSKFDKSGGRNRAIEYDNFIECCLTVKGLTEKFKEKDTALSGSAIFNYENFMLTVLPFLVA", "length": 335 }, "evidence": [ { "id": "F1N7I6", "url": "https://omabrowser.org/oma/group/F1N7I6/", "database": "OMA" } ], "glygen_name": "Arabidopsis", "common_name": "Mouse-ear cress" } ], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 2, "go_terms": [ { "name": "cytosol", "id": "GO:0005829", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005829", "evidence": [ { "database": "UniProtKB", "id": "F1N7I6", "url": "https://www.uniprot.org/uniprotkb/F1N7I6" } ], "pmid": "" }, { "name": "endomembrane system", "id": "GO:0012505", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0012505", "evidence": [ { "database": "UniProtKB", "id": "F1N7I6", "url": "https://www.uniprot.org/uniprotkb/F1N7I6" } ], "pmid": "" } ] }, { "name": "Molecular Function", "total": 3, "go_terms": [ { "name": "protein homodimerization activity", "id": "GO:0042803", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0042803", "evidence": [ { "database": "UniProtKB", "id": "F1N7I6", "url": "https://www.uniprot.org/uniprotkb/F1N7I6" } ], "pmid": "" }, { "name": "protein heterodimerization activity", "id": "GO:0046982", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0046982", "evidence": [ { "database": "UniProtKB", "id": "F1N7I6", "url": "https://www.uniprot.org/uniprotkb/F1N7I6" } ], "pmid": "" }, { "name": "calcium ion binding", "id": "GO:0005509", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005509", "evidence": [ { "database": "UniProtKB", "id": "F1N7I6", "url": "https://www.uniprot.org/uniprotkb/F1N7I6" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [ { "pdb_id": "AF-F1N7I6-F1", "pdb_chain": "global", "start_pos": 1, "end_pos": 201, "overlap": "1.0", "method": "AlphaFold", "type": "alphafold", "resolution": -1.0, "url": "https://data.glygen.org/ln2downloads/pdb/current/AF-F1N7I6-F1.pdb", "url_external": "https://alphafold.ebi.ac.uk/entry/F1N7I6" } ], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "F1N7I6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1N7I6" }, { "id": "PS50222", "database": "PROSITE", "url": "https://prosite.expasy.org/PS50222" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "EF-hand", "eco_id": "ECO_0000259", "start_pos": 73, "end_pos": 108, "start_aa": "Phe", "end_aa": "Trp", "glycosite_overlap": [] } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "homologset.oma", "label": "OMA Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ], "tool_support": { "graph_view": "yes" } }, { "uniprot_canonical_ac": "F1N7K0-1", "uniprot_ac": "F1N7K0", "uniprot_id": "F1N7K0_BOVIN", "mass": { "chemical_mass": 62245.0, "monoisotopic_mass": 62245.0 }, "refseq": { "ac": "NP_001178282", "name": "zinc finger protein 570", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001178282" }, "gene_names": [ { "name": "ZNF570", "type": "recommended", "evidence": [ { "id": "F1N7K0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1N7K0" } ] }, { "name": "ZNF570", "type": "synonym", "evidence": [ { "id": "NP_001178282", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001178282" } ] } ], "protein_names": [ { "name": "Zinc finger protein 570", "type": "synonym", "evidence": [ { "id": "F1N7K0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1N7K0/entry#names_and_taxonomy" } ] }, { "name": "zinc finger protein 570", "type": "synonym", "evidence": [ { "id": "NP_001178282", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001178282" } ] } ], "function": [ { "annotation": "May be involved in transcriptional regulation.", "evidence": [ { "database": "UniProtKB", "id": "F1N7K0", "url": "https://www.uniprot.org/uniprotkb/F1N7K0#function" }, { "database": "UniProtKB", "id": "ARBA00003767", "url": "https://www.uniprot.org/uniprotkb/ARBA00003767#function" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Bos taurus", "taxid": 9913, "evidence": [ { "database": "UniProtKB", "id": "F1N7K0", "url": "https://www.uniprot.org/uniprotkb/F1N7K0" } ], "common_name": "Bovine", "glygen_name": "Bovine", "reference_species": "Bos taurus [9913]" } ], "gene": [ { "name": "ZNF570", "url": "https://www.uniprot.org/uniprotkb/F1N7K0", "locus": { "chromosome": "18", "start_pos": 47471873, "end_pos": 47451484, "strand": "-", "evidence": [ { "database": "Ensembl Gene", "id": "ENSBTAG00000000472", "url": "https://www.ensembl.org/id/ENSBTAG00000000472" } ] } } ], "crossref": [ { "id": "F1N7K0", "url": "https://alphafold.ebi.ac.uk/entry/F1N7K0", "database": "AlphaFoldDB", "categories": [] }, { "id": "ENSBTAG00000000472", "url": "https://bgee.org/?page=gene&gene_id=ENSBTAG00000000472", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "cd07765", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd07765", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "100138971", "url": "https://www.ncbi.nlm.nih.gov/gene/100138971", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR001909", "url": "https://www.ebi.ac.uk/interpro/entry/IPR001909", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR013087", "url": "https://www.ebi.ac.uk/interpro/entry/IPR013087", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR036051", "url": "https://www.ebi.ac.uk/interpro/entry/IPR036051", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR036236", "url": "https://www.ebi.ac.uk/interpro/entry/IPR036236", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "bta:100138971", "url": "https://www.genome.jp/dbget-bin/www_bget?bta:100138971", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "CSGWESM", "url": "https://omabrowser.org/oma/group/CSGWESM/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "F1N7K0", "url": "https://www.orthodb.org/?gene=F1N7K0", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR14003", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR14003", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR14003:SF23", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR14003:SF23", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00096", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00096", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF01352", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF01352", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "R-BTA-212436", "url": "https://www.reactome.org/PathwayBrowser/#R-BTA-212436", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "NP_001178282", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001178282", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "F1N7K0", "url": "https://www.uniprot.org/uniprotkb/F1N7K0", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "F1N7K0-1", "url": "https://www.uniprot.org/uniprotkb/F1N7K0-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MAVGLLKAMYQELVTFRDVAVDFSQEEWDYLNPSQRHLYSNVMLENYRILVSLGLCFSKPSVILLLEQGKEPWMAKREMTKDLCSDWESMCETEELTPKQDIYEPQSSQKVIEKLTSYGLEYSSLKEEWKCEGHLEGQPMNQKACFKEETITHEEAPVNERGQEYNKTWRSFHPNTLLHTQQIIPKEEKVHKHNTHKSLKKKLIAIKPKSIYTEKKLLKCNDCEKVFSQSSSLTLHQRIHTGEKPYKCVECGKAFSQRSNLVQHQRIHTGEKPYECKECRKAFSQNAHLVQHLRVHTGEKPYECKVCRKAFSQFAYLAQHQRVHTGEKPYECIECGKAFSNRSSIAQHQRVHTGEKPYECNVCGKAFSLRAYLTVHQRIHTGERPYECKECGKAFSQNSHLAQHQRIHTGEKPYKCQQCRKAFSQIAYLAQHQRVHTGEKPYECIKCGKAFSNDSSLTQHQRVHTGEKPYECNVCGKAFSYCGSLAQHQRIHTGERPYECKECKKTFRQHAHLAHHQRIHLGESLSPPNPVSHQVL", "length": 536, "header": "tr|F1N7K0-1|F1N7K0_BOVIN Isoform 1 of Zinc finger protein 570 OS=Bos taurus OX=9913 GN=ZNF570 PE=3 SV=2 CANONICAL=F1N7K0-1" }, "isoforms": [ { "isoform_ac": "F1N7K0-1", "url": "https://www.uniprot.org/uniprotkb/F1N7K0/entry", "sequence": { "sequence": "MAVGLLKAMYQELVTFRDVAVDFSQEEWDYLNPSQRHLYSNVMLENYRILVSLGLCFSKPSVILLLEQGKEPWMAKREMTKDLCSDWESMCETEELTPKQDIYEPQSSQKVIEKLTSYGLEYSSLKEEWKCEGHLEGQPMNQKACFKEETITHEEAPVNERGQEYNKTWRSFHPNTLLHTQQIIPKEEKVHKHNTHKSLKKKLIAIKPKSIYTEKKLLKCNDCEKVFSQSSSLTLHQRIHTGEKPYKCVECGKAFSQRSNLVQHQRIHTGEKPYECKECRKAFSQNAHLVQHLRVHTGEKPYECKVCRKAFSQFAYLAQHQRVHTGEKPYECIECGKAFSNRSSIAQHQRVHTGEKPYECNVCGKAFSLRAYLTVHQRIHTGERPYECKECGKAFSQNSHLAQHQRIHTGEKPYKCQQCRKAFSQIAYLAQHQRVHTGEKPYECIKCGKAFSNDSSLTQHQRVHTGEKPYECNVCGKAFSYCGSLAQHQRIHTGERPYECKECKKTFRQHAHLAHHQRIHLGESLSPPNPVSHQVL", "length": 536, "header": "tr|F1N7K0-1|F1N7K0_BOVIN Isoform 1 of Zinc finger protein 570 OS=Bos taurus OX=9913 GN=ZNF570 PE=3 SV=2 CANONICAL=F1N7K0-1" }, "locus": { "chromosome": "18", "start_pos": 47471030, "end_pos": 47452859, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000000598.8", "url": "https://www.ensembl.org/id/ENSBTAT00000000598.8" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000000598.5", "url": "https://www.ensembl.org/id/ENSBTAP00000000598.5" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [ { "id": "bta:100138971", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?bta:100138971", "resource": "KEGG Pathway" }, { "id": "R-BTA-212436", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-BTA-212436", "resource": "Reactome", "description": "Generic Transcription Pathway" } ], "orthologs": [ { "uniprot_canonical_ac": "Q96NI8-1", "protein_name": "Zinc finger protein 570", "gene_name": "ZNF570", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MAVGLLKAMYQELVTFRDVAVDFSQEEWDCLDSSQRHLYSNVMLENYRILVSLGLCFSKPSVILLLEQGKAPWMVKRELTKGLCSGWEPICETEELTPKQDFYEEHQSQKIIETLTSYNLEYSSLREEWKCEGYFERQPGNQKACFKEEIITHEEPLFDEREQEYKSWGSFHQNPLLCTQKIIPKEEKVHKHDTQKRSFKKNLMAIKPKSVCAEKKLLKCNDCEKVFSQSSSLTLHQRIHTGEKPYKCIECGKAFSQRSNLVQHQRIHTGEKPYECKECRKAFSQNAHLVQHLRVHTGEKPYECKVCRKAFSQFAYLAQHQRVHTGEKPYECIECGKAFSNRSSIAQHQRVHTGEKPYECNVCGKAFSLRAYLTVHQRIHTGERPYECKECGKAFSQNSHLAQHQRIHTGEKPYKCQECRKAFSQIAYLAQHQRVHTGEKPYECIECGKAFSNDSSLTQHQRVHTGEKPYECTVCGKAFSYCGSLAQHQRIHTGERPYECKECKKTFRQHAHLAHHQRIHIGESLSPPNPVNHQVL", "length": 536 }, "evidence": [ { "id": "F1N7K0", "url": "https://omabrowser.org/oma/group/F1N7K0/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" } ], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 1, "go_terms": [ { "name": "nucleus", "id": "GO:0005634", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005634", "evidence": [ { "database": "UniProtKB", "id": "F1N7K0", "url": "https://www.uniprot.org/uniprotkb/F1N7K0" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 2, "go_terms": [ { "name": "DNA-templated transcription", "id": "GO:0006351", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006351", "evidence": [ { "database": "UniProtKB", "id": "F1N7K0", "url": "https://www.uniprot.org/uniprotkb/F1N7K0" } ], "pmid": "" }, { "name": "regulation of transcription by RNA polymerase II", "id": "GO:0006357", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006357", "evidence": [ { "database": "UniProtKB", "id": "F1N7K0", "url": "https://www.uniprot.org/uniprotkb/F1N7K0" } ], "pmid": "" } ] }, { "name": "Molecular Function", "total": 3, "go_terms": [ { "name": "zinc ion binding", "id": "GO:0008270", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008270", "evidence": [ { "database": "UniProtKB", "id": "F1N7K0", "url": "https://www.uniprot.org/uniprotkb/F1N7K0" } ], "pmid": "" }, { "name": "RNA polymerase II cis-regulatory region sequence-specific DNA binding", "id": "GO:0000978", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000978", "evidence": [ { "database": "UniProtKB", "id": "F1N7K0", "url": "https://www.uniprot.org/uniprotkb/F1N7K0" } ], "pmid": "" }, { "name": "DNA-binding transcription factor activity, RNA polymerase II-specific", "id": "GO:0000981", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000981", "evidence": [ { "database": "UniProtKB", "id": "F1N7K0", "url": "https://www.uniprot.org/uniprotkb/F1N7K0" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 166, "end_pos": 168, "annotation": "n_glycosylation_sequon" }, { "start_pos": 341, "end_pos": 343, "annotation": "n_glycosylation_sequon" }, { "start_pos": 453, "end_pos": 455, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [ { "pdb_id": "AF-F1N7K0-F1", "pdb_chain": "global", "start_pos": 1, "end_pos": 536, "overlap": "1.0", "method": "AlphaFold", "type": "alphafold", "resolution": -1.0, "url": "https://data.glygen.org/ln2downloads/pdb/current/AF-F1N7K0-F1.pdb", "url_external": "https://alphafold.ebi.ac.uk/entry/F1N7K0" } ], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "F1N7K0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1N7K0" }, { "id": "PS50157", "database": "PROSITE", "url": "https://prosite.expasy.org/PS50157" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "C2H2-type", "eco_id": "ECO_0000259", "start_pos": 218, "end_pos": 245, "start_aa": "Leu", "end_aa": "Pro", "glycosite_overlap": [] }, { "evidence": [ { "id": "F1N7K0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1N7K0" }, { "id": "PS50805", "database": "PROSITE", "url": "https://prosite.expasy.org/PS50805" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "KRAB", "eco_id": "ECO_0000259", "start_pos": 14, "end_pos": 85, "start_aa": "Val", "end_aa": "Ser", "glycosite_overlap": [] } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "homologset.oma", "label": "OMA Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 166, "end_pos": 168 }, { "start_pos": 341, "end_pos": 343 }, { "start_pos": 453, "end_pos": 455 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ 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"count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ], "tool_support": { "graph_view": "yes" } }, { "uniprot_canonical_ac": "F1N7K7-1", "uniprot_ac": "F1N7K7", "uniprot_id": "F1N7K7_BOVIN", "mass": { "chemical_mass": 46800.0, "monoisotopic_mass": 46800.0 }, "refseq": {}, "gene_names": [ { "name": "MARCO", "type": "recommended", "evidence": [ { "id": "F1N7K7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1N7K7" } ] } ], "protein_names": [ { "name": "Macrophage receptor with collagenous structure", "type": "synonym", "evidence": [ { "id": "F1N7K7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1N7K7/entry#names_and_taxonomy" } ] } ], "function": [], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Bos taurus", "taxid": 9913, "evidence": [ { "database": "UniProtKB", "id": "F1N7K7", "url": "https://www.uniprot.org/uniprotkb/F1N7K7" } ], "common_name": "Bovine", "glygen_name": "Bovine", "reference_species": "Bos taurus [9913]" } ], "gene": [ { "name": "MARCO", "url": "https://www.uniprot.org/uniprotkb/F1N7K7", "locus": { "chromosome": "2", "start_pos": 70770454, "end_pos": 70736121, "strand": "-", "evidence": [ { "database": "Ensembl Gene", "id": "ENSBTAG00000018473", "url": "https://www.ensembl.org/id/ENSBTAG00000018473" } ] } } ], "crossref": [ { "id": "F1N7K7", "url": "https://alphafold.ebi.ac.uk/entry/F1N7K7", "database": "AlphaFoldDB", "categories": [] }, { "id": "ENSBTAG00000018473", "url": "https://bgee.org/?page=gene&gene_id=ENSBTAG00000018473", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "IPR001190", "url": "https://www.ebi.ac.uk/interpro/entry/IPR001190", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR008160", "url": "https://www.ebi.ac.uk/interpro/entry/IPR008160", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR036772", "url": "https://www.ebi.ac.uk/interpro/entry/IPR036772", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "bta:505632", "url": "https://www.genome.jp/dbget-bin/www_bget?bta:505632", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "GMFGIKG", "url": "https://omabrowser.org/oma/group/GMFGIKG/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "F1N7K7", "url": "https://www.orthodb.org/?gene=F1N7K7", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR48071", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR48071", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR48071:SF18", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR48071:SF18", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00530", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00530", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF01391", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF01391", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "F1N7K7", "url": "https://www.uniprot.org/uniprotkb/F1N7K7", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "F1N7K7-1", "url": "https://www.uniprot.org/uniprotkb/F1N7K7-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MENEEILKEKELLASTEDGTALDQTMLSRMETFEVNDPKPKRRNGMNCIMVLVILYLVLLTAGAGLLVIQVLNLQERLRVLEMPYNNETQAQLTQVVTKQETLQQRMDNFIQIPGWSLPTEFGLFRENGRPPGPRGPPGIKGEAGEQGLGVCASQAAACLGAAATHTPHPESLNSEWGLCVREVTWGETLHVLGCWEFLGFSGRKGDMGMKGDMGPPGARGDKGDSGKPGFPGVAGIPGIKGDQGPPGMKGLPGFPGAVGSPGAKGDTGSIGPTGPIGPPGLPGTPGVEGVKGSKGDTGNRGLSGVKGEKGSPGLGGLKGAPGPTGQKGEPGSRGATGPQGAKGEKGQKGDSSLSVRIIGSRNRGRAEVFYNGAWGTICDDSWDGSDATVFCRMLGYSSGSPVYNVGAGSGNIWLDDVACSGSEWTLWDCNKSSWGSHNCNHNEDAGVNCS", "length": 451, "header": "tr|F1N7K7-1|F1N7K7_BOVIN Isoform 1 of Macrophage receptor with collagenous structure OS=Bos taurus OX=9913 GN=MARCO PE=4 SV=4 CANONICAL=F1N7K7-1" }, "isoforms": [ { "isoform_ac": "F1N7K7-1", "url": "https://www.uniprot.org/uniprotkb/F1N7K7/entry", "sequence": { "sequence": "MENEEILKEKELLASTEDGTALDQTMLSRMETFEVNDPKPKRRNGMNCIMVLVILYLVLLTAGAGLLVIQVLNLQERLRVLEMPYNNETQAQLTQVVTKQETLQQRMDNFIQIPGWSLPTEFGLFRENGRPPGPRGPPGIKGEAGEQGLGVCASQAAACLGAAATHTPHPESLNSEWGLCVREVTWGETLHVLGCWEFLGFSGRKGDMGMKGDMGPPGARGDKGDSGKPGFPGVAGIPGIKGDQGPPGMKGLPGFPGAVGSPGAKGDTGSIGPTGPIGPPGLPGTPGVEGVKGSKGDTGNRGLSGVKGEKGSPGLGGLKGAPGPTGQKGEPGSRGATGPQGAKGEKGQKGDSSLSVRIIGSRNRGRAEVFYNGAWGTICDDSWDGSDATVFCRMLGYSSGSPVYNVGAGSGNIWLDDVACSGSEWTLWDCNKSSWGSHNCNHNEDAGVNCS", "length": 451, "header": "tr|F1N7K7-1|F1N7K7_BOVIN Isoform 1 of Macrophage receptor with collagenous structure OS=Bos taurus OX=9913 GN=MARCO PE=4 SV=4 CANONICAL=F1N7K7-1" }, "locus": { "chromosome": "2", "start_pos": 70769483, "end_pos": 70736330, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000024586.8", "url": "https://www.ensembl.org/id/ENSBTAT00000024586.8" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000024586.7", "url": "https://www.ensembl.org/id/ENSBTAP00000024586.7" } ] } } ], "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "other", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 274, "start_aa": "Thr", "end_pos": 274, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr274", "evidence": [ { "id": "", "database": "GlyGen", "url": "https://data.glygen.org/" } ], "filter_code": "000000000000000010000.00000000001000.0.01000" }, { "glytoucan_ac": "", "type": "O-linked", "subtype": "other", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 285, "start_aa": "Thr", "end_pos": 285, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr285", "evidence": [ { "id": "", "database": "GlyGen", "url": "https://data.glygen.org/" } ], "filter_code": "000000000000000010000.00000000001000.0.01000" }, { "glytoucan_ac": "", "type": "O-linked", "subtype": "other", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 325, "start_aa": "Thr", "end_pos": 325, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr325", "evidence": [ { "id": "", "database": "GlyGen", "url": "https://data.glygen.org/" } ], "filter_code": "000000000000000010000.00000000001000.0.01000" } ], "phosphorylation": [], "glycation": [], "keywords": [ "glycoprotein", "glycoprotein_predicted" ], "publication": [], "pathway": [ { "id": "bta:505632", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?bta:505632", "resource": "KEGG Pathway" } ], "orthologs": [ { "uniprot_canonical_ac": "M0R9F7-1", "protein_name": "Macrophage receptor with collagenous structure", "gene_name": "Marco", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MGSKETLKEEAFLGSTEDGADFDQDMLPVMETFEINDPVPKKRNGRTLCMAVMAIHLILLTAGTALLLIQVLNLQEQFQSLEMCCDNGTLAAEDKPFFSLQWARPKTHIVSGAQGLQALQAQLSWVHTSQEQLRQQVDNLTQNPELFRIKGERGSPGPKGAPGAPGIPGLPGPSAAKGEKGAAGRDGTPGVRGPQGPPGTKGEAGLQGFTGAPGKQGADGAPGPQGEKGSKGDKGLTGPKGEHGTKGDKGDLGLPGSKGDTGMKGDRGVTGSPGAQGNKGDAGKPGLPGLAGSPGAKGDQGKLGVQGPPGPPGAPGQSGAKGEPGRTGPPGPTGPPGIAGNPGAAGLKGSKGDIGIQGQKGTKGESGVPGLVGRKGDTGSPGLAGPKGEPGRAGLKGEPGMKGSSGQQGQKGEKGQKGDFNLVVRIVGGTSRGRAEVYYNNVWGTICDDGWDNNDATVFCRMLGYSSGRGLGSFGGGTGKIWLDDVSCLGTEATLWDCRKSSWGSHNCNHNEDAGVECR", "length": 519 }, "evidence": [ { "id": "F1N7K7", "url": "https://omabrowser.org/oma/group/F1N7K7/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "Q60754-1", "protein_name": "Macrophage receptor MARCO", "gene_name": "Marco", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MGSKELLKEEDFLGSTEDRADFDQAMFPVMETFEINDPVPKKRNGGTFCMAVMAIHLILLTAGTALLLIQVLNLQEQLQMLEMCCGNGSLAIEDKPFFSLQWAPKTHLVPRAQGLQALQAQLSWVHTSQEQLRQQFNNLTQNPELFQIKGERGSPGPKGAPGAPGIPGLPGPAAEKGEKGAAGRDGTPGVQGPQGPPGSKGEAGLQGLTGAPGKQGATGAPGPRGEKGSKGDIGLTGPKGEHGTKGDKGDLGLPGNKGDMGMKGDTGPMGSPGAQGGKGDAGKPGLPGLAGSPGVKGDQGKPGVQGVPGPQGAPGLSGAKGEPGRTGLPGPAGPPGIAGNPGIAGVKGSKGDTGIQGQKGTKGESGVPGLVGRKGDTGSPGLAGPKGEPGRVGQKGDPGMKGSSGQQGQKGEKGQKGESFQRVRIMGGTNRGRAEVYYNNEWGTICDDDWDNNDATVFCRMLGYSRGRALSSYGGGSGNIWLDNVNCRGTENSLWDCSKNSWGNHNCVHNEDAGVECS", "length": 518 }, "evidence": [ { "id": "F1N7K7", "url": "https://omabrowser.org/oma/group/F1N7K7/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q9UEW3-1", "protein_name": "Macrophage receptor MARCO", "gene_name": "MARCO", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": 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"count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { 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"RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_005205922" } ] } ], "protein_names": [ { "name": "TRPM8 channel associated factor 1", "type": "synonym", "evidence": [ { "id": "F1N7N3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1N7N3/entry#names_and_taxonomy" } ] }, { "name": "TRPM8 channel-associated factor 1 isoform X1", "type": "synonym", "evidence": [ { "id": "XP_005205922", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_005205922" } ] } ], "function": [], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Bos taurus", "taxid": 9913, "evidence": [ { "database": "UniProtKB", "id": "F1N7N3", "url": "https://www.uniprot.org/uniprotkb/F1N7N3" } ], "common_name": "Bovine", "glygen_name": "Bovine", "reference_species": "Bos taurus [9913]" } ], "gene": [ { "name": "TCAF1", "url": "https://www.uniprot.org/uniprotkb/F1N7N3", "locus": { "chromosome": "4", "start_pos": 107019305, "end_pos": 107044650, "strand": "+", "evidence": [ { "database": "Ensembl Gene", "id": "ENSBTAG00000002554", "url": "https://www.ensembl.org/id/ENSBTAG00000002554" } ] } } ], "crossref": [ { "id": "F1N7N3", "url": "https://alphafold.ebi.ac.uk/entry/F1N7N3", "database": "AlphaFoldDB", "categories": [] }, { "id": "ENSBTAG00000002554", "url": "https://bgee.org/?page=gene&gene_id=ENSBTAG00000002554", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "533126", "url": "https://www.ncbi.nlm.nih.gov/gene/533126", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR029062", "url": "https://www.ebi.ac.uk/interpro/entry/IPR029062", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR031161", "url": "https://www.ebi.ac.uk/interpro/entry/IPR031161", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR035423", "url": "https://www.ebi.ac.uk/interpro/entry/IPR035423", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR042279", "url": "https://www.ebi.ac.uk/interpro/entry/IPR042279", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR051244", "url": "https://www.ebi.ac.uk/interpro/entry/IPR051244", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "YMAIPAE", "url": "https://omabrowser.org/oma/group/YMAIPAE/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "F1N7N3", "url": "https://www.orthodb.org/?gene=F1N7N3", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR15730", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR15730", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR15730:SF1", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR15730:SF1", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF13402", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF13402", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF17291", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF17291", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF27016", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF27016", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF27027", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF27027", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "XP_005205922", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_005205922", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "F1N7N3", "url": "https://www.uniprot.org/uniprotkb/F1N7N3", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "F1N7N3-1", "url": "https://www.uniprot.org/uniprotkb/F1N7N3-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MATPSAAFEALMNGVTSWNVPEDAVPCELLLIGEASFPVMVNDMGQVLIAASSYGRGRLVVVSHEDYLVEAQLTPFLLNAVGWLCSSPGAPVGVHPSLAPLAKILEGSGVEAKVEPEVKDSLGVYCIDAYNETMTEKLVKFMKRGGGLLIGGQAWDWANQGDDERVLFTFPGNLVTSVAGVYFTDNKGDTSFFKVSKKMPKIPVLVSCEDDLSEDRDELLHGISELDITNSDCFPSQLLVHGALAFPLGLDSYHGCVIAAARYGRGRVVVTGHKVLFTVGKLGPFLLNAVRWLDAGRRGKIVVQTELRTLSGLLAVGGIDTSIEPNLTSDASVYCFEPVSDVGVKELQEFVAEGGGLFVGAQAWWWAFKNPGVSPLARFPGNLLLNPFGISITSQSLNPGPFRTPKAGIRTYHFRSTLAEFQVIMGRKRGNVEKGWLAKLGPDGAAFLQIPAEEIPAYMSVHRLLRKLLSRYRLPVATRENPVINDCCRGAMLSLATGLAHSGSDLSLLVPEIEDMYSSPYLRPSESPITVEVNCNNPGTRYCWMSTGLYIPGRQIIEVSLPEAAASADLKIQIGCHTDDLTRASKLFRGPLVINRCCLDKPTKSITCLWGGLLYIIVPQSSKLGTVPVTIKGAVRAPYYKLGETTQEEWKRQIQENPGPWGELATDNIILTVPTANLRTLENPEPLLRLWDEVMQAVARLGAEPFPLRLPQRIVADVQISVGWMHAGYPIMCHLESVQELINEKLIRTKGLWGPVHELGRNQQRQEWEFPPHTTEATCNLWCVYVHETVLGIPRGRANIALWPPVREKRVRIYLGKGPNVKNWNAWTALETYLQLQEAFGWEPFIRLFTEYRNQTNLPTDNVDKMNLWVKMFSHQVQKNLAPFFEAWAWPIQKEVATSLAYLPEWKENIMKLYLLTQMPH", "length": 921, "header": "tr|F1N7N3-1|F1N7N3_BOVIN Isoform 1 of TRPM8 channel associated factor 1 OS=Bos taurus OX=9913 GN=TCAF1 PE=3 SV=1 CANONICAL=F1N7N3-1" }, "isoforms": [ { "isoform_ac": "F1N7N3-1", "url": "https://www.uniprot.org/uniprotkb/F1N7N3/entry", "sequence": { "sequence": "MATPSAAFEALMNGVTSWNVPEDAVPCELLLIGEASFPVMVNDMGQVLIAASSYGRGRLVVVSHEDYLVEAQLTPFLLNAVGWLCSSPGAPVGVHPSLAPLAKILEGSGVEAKVEPEVKDSLGVYCIDAYNETMTEKLVKFMKRGGGLLIGGQAWDWANQGDDERVLFTFPGNLVTSVAGVYFTDNKGDTSFFKVSKKMPKIPVLVSCEDDLSEDRDELLHGISELDITNSDCFPSQLLVHGALAFPLGLDSYHGCVIAAARYGRGRVVVTGHKVLFTVGKLGPFLLNAVRWLDAGRRGKIVVQTELRTLSGLLAVGGIDTSIEPNLTSDASVYCFEPVSDVGVKELQEFVAEGGGLFVGAQAWWWAFKNPGVSPLARFPGNLLLNPFGISITSQSLNPGPFRTPKAGIRTYHFRSTLAEFQVIMGRKRGNVEKGWLAKLGPDGAAFLQIPAEEIPAYMSVHRLLRKLLSRYRLPVATRENPVINDCCRGAMLSLATGLAHSGSDLSLLVPEIEDMYSSPYLRPSESPITVEVNCNNPGTRYCWMSTGLYIPGRQIIEVSLPEAAASADLKIQIGCHTDDLTRASKLFRGPLVINRCCLDKPTKSITCLWGGLLYIIVPQSSKLGTVPVTIKGAVRAPYYKLGETTQEEWKRQIQENPGPWGELATDNIILTVPTANLRTLENPEPLLRLWDEVMQAVARLGAEPFPLRLPQRIVADVQISVGWMHAGYPIMCHLESVQELINEKLIRTKGLWGPVHELGRNQQRQEWEFPPHTTEATCNLWCVYVHETVLGIPRGRANIALWPPVREKRVRIYLGKGPNVKNWNAWTALETYLQLQEAFGWEPFIRLFTEYRNQTNLPTDNVDKMNLWVKMFSHQVQKNLAPFFEAWAWPIQKEVATSLAYLPEWKENIMKLYLLTQMPH", "length": 921, "header": "tr|F1N7N3-1|F1N7N3_BOVIN Isoform 1 of TRPM8 channel associated factor 1 OS=Bos taurus OX=9913 GN=TCAF1 PE=3 SV=1 CANONICAL=F1N7N3-1" }, "locus": { "chromosome": "4", "start_pos": 107044636, "end_pos": 107022042, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000057182.3", "url": "https://www.ensembl.org/id/ENSBTAT00000057182.3" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000050827.1", "url": "https://www.ensembl.org/id/ENSBTAP00000050827.1" } ] } } ], "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "other", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 3, "start_aa": "Thr", "end_pos": 3, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr3", "evidence": [ { "id": "", "database": "GlyGen", "url": "https://data.glygen.org/" } ], "filter_code": "000000000000000010000.00000000001000.0.01000" } ], "phosphorylation": [], "glycation": [], "keywords": [ "glycoprotein", "glycoprotein_predicted" ], "publication": [], "pathway": [], "orthologs": [ { "uniprot_canonical_ac": "A0A9J7F1V5-1", "protein_name": "TRPM8 channel-associated factor 1 isoform X1", "gene_name": "LOC100753518", "tax_id": 10029, "organism": "Cricetulus griseus", "sequence": { "sequence": "MATPSAAFEALMTGVTSWDIPEDAIPCELLLIGESSFPVMVNDMGQVLIAASSYGRGRMVVVAHEDYLVESQLFVFLVNAIGWLRSSPESSIGIHTSLSPLVKILESCGIESTIEPEANDSIGVYCIDAYHESMSDKLVQFVKRGGGLLIGGQAWDWANQGEDERILFTFPGNLVTSVAGVYFTDNKADSTVFKVSKKMPKIPVLVSCEDDLSEDRDELLHGISELDITNSDCFPSQLLVHGALAFPLGLDTYHGCVIAAARYGRGRVVVTGHKVLFTVGKLGPFLLNAVRWLDGGRRGKIVVQTELRTLSGLLAVGGIDTSIEPQLTSDASVYCFEPTSDVGVKELQEFVAEGGGLFVGAQAWWWAFKNPGVSPLARFPGNLLLNPFGISITSQSLNPGPFRTPKLGIRTYHFRSTLAEFEVIMGRKRGNVEKGWLAKLGPDGAAFLQIPAEEIPAYMSVHRLLRKLLSRYRLPVATRENPVINDCCRGAMLSLATGLAHSGSDLSLLVPEIEDMHSSLYLRPSESPITVDVNCTNRGTRYCWMSTALYIPGRQIIEVSLPEDAASADLKIQIGCHTDDLTRASKLFRGPLVINRCCLDKPVKSITCLWGGLLYIIVPQNSKLGSVPITVKGAVRAPYYKLGETSQEEWKRRLQEHPGPWGELATDNLILTVPTANLRALENPEPLLRLWDDVMQAVARLGGEPFPLRLPQRIVADVQISVGWMHAGYPIMCHLESVQELINEKLIRTKGLWGPVHELGRNQQRQEWEFPPHTTEATCNLWCVYVHETVLGIPRSRANIALWPPVREKRVRIYLSKGPNIKNWNAWTALETYLQLQEAFGWEPFIRLFTEYRNQTNLPTDTADKMNLWAKMFSQQVQKNLAPFFEAWAWPIQKELATSLAYLPEWKENIMKLYLLTQMPQ", "length": 921 }, "evidence": [ { "id": "F1N7N3", "url": "https://omabrowser.org/oma/group/F1N7N3/", "database": "OMA" } ], "glygen_name": "Hamster", "common_name": "Chinese hamster" }, { "uniprot_canonical_ac": "A4IG42-1", "protein_name": "TRPM8 channel-associated factor homolog", "gene_name": "tcaf", "tax_id": 7955, "organism": "Danio rerio", "sequence": { "sequence": "MAREQDYYTLMSGMQQLDLQGKAVPSDLVLIGEHAFPLAMNPRGQVLMAASHYGRGRIVVLGHEEYLTRFPGLIENAIMWLMPCTGDAGVVGIQKSLRTVAENLNYSPFKTELGDFQDRFAIYITDAYSVESSAKDLIAFLKAGGGLIIAGQAWSWSYEHPQENTIRNFPGNKVCSVAGIYFSELEGEVGTFPVPRNIPSSWLAVAIGKDFKEDLEFLLEGVSEFDTQGGAIASEVMVHGPLAFPIAVTPNGKTFIAGAYYGQGRVIVVSHEGYMGRDSLSSFMINAIKWLDEGRKGVVGIVPNLTAAHTVLSKSGLDCQLTGFREDLSVYVCTSYSDAQCAEIQEFVAEGGGLLIGGHAWYWAQTHCGSNVMTEYPGNHILNKMGLCLLGNTLGGGLYKAPEIEHSCKHGYHFRSMLQRFAQHVSQGQELTDREQGCLKQLGTDCASYLQMRCHDSAAYTSVVALLSDIVKEVGVPQVCSNCPVESPKDHLMLHIGTEVYKVTPDPDALLPYIIKDRPNLPTLSNARVRITANTGGCEEWISTGLYLSPGMKTYIAVPPEIVGKNWQVQLGCQTDNIGGSNTLKRAPVVHARFPLDSEMVQVWNLWGGLIYLIAPSQTKVDGVEIVVQNAVQAPYFKSGETSVADWVSHIRQAPAPWAELEFENLIMTFDSAFIRNLDRPDEVAKLWDTIMRTITDLAARPPKLPRKERFVADVQISYGFMHAGYPIMMHSGSAPGLVNVEEAYKCGLWGAIHELGHNQQRGVWEFPPHTTECTCNLWSLYVHEQVFGIKSANAHPAITPADRQARTKMYFDGGKDLNSWCMWMALETYMQLQEKFGWDAFKKVFSLYHDMTGVPNDNAGKMNLYAQTFSKVVNLNLSPFFKAWGWPIQPNTEQNLSHLPAWSDHPVSQYA", "length": 912 }, "evidence": [ { "id": "F1N7N3", "url": "https://omabrowser.org/oma/group/F1N7N3/", "database": "OMA" } ], "glygen_name": "Zebrafish", "common_name": "Zebrafish" }, { "uniprot_canonical_ac": "D3Z8A4-1", "protein_name": "TRPM8 channel-associated factor 1", "gene_name": "Tcaf1", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MLSLLSPPPATQRSSFTCQAPPLGLLLWPGGSGEETAWEPLLSSRSDLLPVKLQAFGGCSGAPWCSTEKPLFSPPGAVLEAPRQLPGTNRTMATPSATFEALMNGVTSWDIPDDSVPCELLLIGEASFPIMVNDVGQVLIAASSYGRGRMVVASHEDFLVESQLFVFLVNAVGWLRSSSESTIGVHSSLAPLVKILESCGIESKIEPEVNDSLGVYCIDAYNETMTDKLLQFVKRGGGLLIGGQAWDWDNLGEDDRVLFSFPGNLVTSVAGVYFTDNKADTNCYKVSKKMPKIPILVRCEDDLSEDRDELLHGISDLDITNSDCFPSQLLVHGSLAFPLGLDTHHGCVIAAARYGRGRVVVTGHKVLFTVGKLGPFLLNAVRWLDGGRRGKIVVQTELRTLSGLLAVGGIDTSIEPQLTSDASVYCFEPTSDVGVKELQEFVAEGGGLFVGTQAWWWAFKNPGVSPLARFPGNLLLNAFGISITSQSLNPGPFHIPKAGTRTYHFRSTLAEFQVIMGRKRGNVEKGWLAKLGPDGAAFLQIPAEEIPAYMSVHRLLRKLLSRYRLPVATRENPVINDCCRGAMLSLATGLAHSGSDLSLLIPEIEDVYSSCYLRPSESPITVDVNCTNPGTRYCWMSTGLYIPGRQVIDVSLPEDAASADLKIQIGCHTDDLTRASKLFRGPLVINRCCLDKPMKSINCLWGGLLYIIVPQNSKLGTVPLTVKGAVRAPFYKLGETSKEEWKRRLLEYPGPWGELATDNLILTVPTANLRTLENPEPLLRLWDEVMQAVAKLGGEPFPLRLPQRIVADVQISVGWMHAGYPIMCHLESVQELISEKLIRTKGLWGPVHELGRNQQRQEWEFPPHTTEATCNLWCVYVHETVLGIPRSRANIALWPPVREKRVRMYLSKGPNVKNWNAWTALETYLQLQEAFGWEPFIRLFTEYRNQTTNSPTDNVNKMNLWVKMFSQQVQKNLAPFFEAWAWPIQKEVATSLAYLPEWKENIMKLYLLTQL", "length": 1011 }, "evidence": [ { "id": "F1N7N3", "url": "https://omabrowser.org/oma/group/F1N7N3/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "Q8BNE1-1", "protein_name": "TRPM8 channel-associated factor 1", "gene_name": "Tcaf1", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MATPSAAFEALMNGVTSWDIPEDSVPCELLLIGEASFPIMVNDVGQVLVAASSYGRGRMVVASHEDFLLESQLFVFLVNAVGWLRSSPNSAIGVHSSLAPLVKILESCGIESKIEPEVNDSLGVYCIDAYNETMTDKLVQFVKRGGGLLIGGEAWDWDTQGDDDRVLFAFPGNLVTSVAGVYFTDNKADTSFFKVSKKMPKIPILVRCDDDLSDDRDELLRGIIDLDITNSDCFPSQLLVHGSLAFPLGLDTYHGCVIAAARYGRGRVVVTGHKVLFTVGKLGPFLLNAVRWLDGGRKGKIVVQTELRTLSGLLAVGGIDTSIEPHLTSDASVYCFEPTSDVGVKELQEFVAEGGGLFVGTQAWWWAFKNPGVSPLARFPGNLLLNAFGISITSQSLNPGPFRTPKIGTRTYHFRSTLAEFQVIMGRKRGNVEKGWLAKLGPDGATFLQIPAEEIPAYMSVHRLLRKLLSRYRLPVATRENPVINDCCRGAMLSLATGLAHSGSDLSLLIPEIEDVYSSRYLRPSASPITVNVNCTNPGTRYCWMSTGLYIPGRQVIDVSVPESAASADLKIQIGCHTDDLTRASKLFRGPLVINRCCLDKPTKSITCLWGGLLYIIVPQNSKLGSVPLTVKGAVRAPFYKLGETSKEEWKRRLLEYPGPWGELATDNIILTVPTANLRTLENPEPLLRLWDEMMQAVAKLGGETFPLRLPQRIVADVQISVGWMHAGYPIMCHLESVQELINEKLIRTKGLWGPVHELGRNQQRQEWEFPPHTTEATCNLWCVYVHETVLGIPRSRANIALWPPVREKRVRIYLSKGPSVKHWNAWTALETYLQLQEAFGWEPFIRLFTEYRNQTTSSSPPSDNVDKMNLWVKMFSQQVQRNLAPFFEAWGWPIQKEVATSLAYLPEWKENIMKLYLLTQMPH", "length": 924 }, "evidence": [ { "id": "F1N7N3", "url": "https://omabrowser.org/oma/group/F1N7N3/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q9Y4C2-1", "protein_name": "TRPM8 channel-associated factor 1", "gene_name": "TCAF1", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MATPSAAFEALMNGVTSWDVPEDAVPCELLLIGEASFPVMVNDMGQVLIAASSYGRGRLVVVSHEDYLVEAQLTPFLLNAVGWLCSSPGAPIGVHPSLAPLAKILEGSGVDAKVEPEVKDSLGVYCIDAYNETMTEKLVKFMKCGGGLLIGGQAWDWANQGEDERVLFTFPGNLVTSVAGIYFTDNKGDTSFFKVSKKMPKIPVLVSCEDDLSDDREELLHGISELDISNSDCFPSQLLVHGALAFPLGLDSYHGCVIAAARYGRGRVVVTGHKVLFTVGKLGPFLLNAVRWLDGGRRGKVVVQTELRTLSGLLAVGGIDTSIEPNLTSDASVYCFEPVSEVGVKELQEFVAEGGGLFVGAQAWWWAFKNPGVSPLARFPGNLLLNPFGISITSQSLNPGPFRTPKAGIRTYHFRSTLAEFQVIMGRKRGNVEKGWLAKLGPDGAAFLQIPAEEIPAYMSVHRLLRKLLSRYRLPVATRENPVINDCCRGAMLSLATGLAHSGSDLSLLVPEIEDMYSSPYLRPSESPITVEVNCTNPGTRYCWMSTGLYIPGRQIIEVSLPEAAASADLKIQIGCHTDDLTRASKLFRGPLVINRCCLDKPTKSITCLWGGLLYIIVPQNSKLGSVPVTVKGAVHAPYYKLGETTLEEWKRRIQENPGPWGELATDNIILTVPTANLRTLENPEPLLRLWDEVMQAVARLGAEPFPLRLPQRIVADVQISVGWMHAGYPIMCHLESVQELINEKLIRTKGLWGPVHELGRNQQRQEWEFPPHTTEATCNLWCVYVHETVLGIPRSRANIALWPPVREKRVRIYLSKGPNVKNWNAWTALETYLQLQEAFGWEPFIRLFTEYRNQTNLPTENVDKMNLWVKMFSHQVQKNLAPFFEAWAWPIQKEVATSLAYLPEWKENIMKLYLLTQMPH", "length": 921 }, "evidence": [ { "id": "F1N7N3", "url": 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"https://www.uniprot.org/uniprotkb/F1N7X6", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "F1N7X6-1", "url": "https://www.uniprot.org/uniprotkb/F1N7X6-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MLSSIKCVLVGDSAVGKTSLLVRFTSETFPEAYKPTVYENTGVDVFMDGIQISLGLWDTAGNDAFRSIRPLSYQQADVVLMCYSVANHNSFLNLKNKWIGEVRSNLPCTPVLVVATQTDQREVGPHRASCVNAIEGKRLAQDVRAKGYLECSALSNRGVQQVFECAVRTAVNQARRRNRRRFFSINECKIL", "length": 191, "header": "tr|F1N7X6-1|F1N7X6_BOVIN Isoform 1 of Rho-related GTP-binding protein RhoH OS=Bos taurus OX=9913 GN=RHOH PE=3 SV=1 CANONICAL=F1N7X6-1" }, "isoforms": [ { "isoform_ac": "F1N7X6-1", "url": "https://www.uniprot.org/uniprotkb/F1N7X6/entry", "sequence": { "sequence": "MLSSIKCVLVGDSAVGKTSLLVRFTSETFPEAYKPTVYENTGVDVFMDGIQISLGLWDTAGNDAFRSIRPLSYQQADVVLMCYSVANHNSFLNLKNKWIGEVRSNLPCTPVLVVATQTDQREVGPHRASCVNAIEGKRLAQDVRAKGYLECSALSNRGVQQVFECAVRTAVNQARRRNRRRFFSINECKIL", "length": 191, "header": "tr|F1N7X6-1|F1N7X6_BOVIN Isoform 1 of Rho-related GTP-binding protein RhoH OS=Bos taurus OX=9913 GN=RHOH PE=3 SV=1 CANONICAL=F1N7X6-1" }, "locus": { "chromosome": "6", "start_pos": 59249621, "end_pos": 59249049, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000115537.1", "url": "https://www.ensembl.org/id/ENSBTAT00000115537.1" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000085248.1", "url": "https://www.ensembl.org/id/ENSBTAP00000085248.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [ { "id": "R-BTA-9013407", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-BTA-9013407", "resource": "Reactome", "description": "RHOH GTPase cycle" } ], "orthologs": [ { "uniprot_canonical_ac": "A0A3Q2UHR2-1", "protein_name": "Rho-related GTP-binding protein RhoH", "gene_name": "RHOH", "tax_id": 9031, "organism": "Gallus gallus", "sequence": { "sequence": 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"Rho-related GTP-binding protein RhoH", "gene_name": "Rhoh", "tax_id": 10029, "organism": "Cricetulus griseus", "sequence": { "sequence": "MLSSIKCVLVGDSAVGKTSLLVRFTSETFPEAYKPTVYENTGVDVFMDGIQISLGLWDTAGNDAFRSIRPLSYQQADVVLMCYSVANHSSFLNLKNKWINEIRSNLPCTPVLVVATQTDQREMGPHRASCINAIDGKRLAQDVRAKGYLECSALSNRGVQQVFECAVRTAVNQARRRNRRKLFSINECKIF", "length": 191 }, "evidence": [ { "id": "F1N7X6", "url": "https://omabrowser.org/oma/group/F1N7X6/", "database": "OMA" } ], "glygen_name": "Hamster", "common_name": "Chinese hamster" }, { "uniprot_canonical_ac": "I3LRS0-1", "protein_name": "Rho-related GTP-binding protein RhoH", "gene_name": "RHOH", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MLSSIKCVLVGDSAVGKTSLLVRFTSETFPEHYKPTVYENTGVDVFMDGIQISLGLWDTAGNDAFRSIRPLSYQQADVVLMCYSVANYNSFLNLKNKWIGEVRNNLPCTPVLVVATQTDQREVGPHRASCVSAVEGKRLAQDVRAKGYLECSALSNRGVQQVFECAVRTAVNQARRRNRRRFFPLNECKIL", "length": 191 }, "evidence": [ { "id": "F1N7X6", "url": "https://omabrowser.org/oma/group/F1N7X6/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "Q15669-1", "protein_name": "Rho-related GTP-binding protein RhoH", "gene_name": "RHOH", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MLSSIKCVLVGDSAVGKTSLLVRFTSETFPEAYKPTVYENTGVDVFMDGIQISLGLWDTAGNDAFRSIRPLSYQQADVVLMCYSVANHNSFLNLKNKWIGEIRSNLPCTPVLVVATQTDQREMGPHRASCVNAMEGKKLAQDVRAKGYLECSALSNRGVQQVFECAVRTAVNQARRRNRRRLFSINECKIF", "length": 191 }, "evidence": [ { "id": "F1N7X6", "url": "https://omabrowser.org/oma/group/F1N7X6/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "Q5BJZ5-1", "protein_name": "Rho-related GTP-binding protein RhoH", "gene_name": "Rhoh", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MLSSIKCVLVGDSAVGKTSLLVRFTSETFPEAYKPTVYENTGVDVFMDGIQISLGLWDTAGNDAFRSIRPLSYQQADVVLMCYSVANHSSFLNLKNKWISEVRSNLPCTPVLVVATQTDQREMGPHRASCINAIEGKRLAQDVRAKGYLECSALSNRGVQQVFECAVRTAVNQARRRNRRKLFSINECKIF", "length": 191 }, "evidence": [ { "id": "F1N7X6", "url": "https://omabrowser.org/oma/group/F1N7X6/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "Q9D3G9-1", "protein_name": "Rho-related GTP-binding protein RhoH", "gene_name": "Rhoh", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MLSSIKCVLVGDSAVGKTSLLVRFTSETFPEAYKPTVYENTGVDVFMDGIQISLGLWDTAGNDAFRSIRPLSYQQADVVLMCYSVANHNSFLNLKNKWISEIRSNLPCTPVLVVATQTDQREVGPHRASCINAIEGKRLAQDVRAKGYLECSALSNRGVQQVFECAVRTAVNQARRRNRRKLFSINECKIF", "length": 191 }, "evidence": [ { "id": "F1N7X6", "url": "https://omabrowser.org/oma/group/F1N7X6/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" } ], "go_annotation": { "categories": [ { "name": "Molecular Function", "total": 4, 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"pmid": "" }, { "name": "signal transduction", "id": "GO:0007165", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007165", "evidence": [ { "database": "UniProtKB", "id": "F1N7X6", "url": "https://www.uniprot.org/uniprotkb/F1N7X6" } ], "pmid": "" }, { "name": "small GTPase-mediated signal transduction", "id": "GO:0007264", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007264", "evidence": [ { "database": "UniProtKB", "id": "F1N7X6", "url": "https://www.uniprot.org/uniprotkb/F1N7X6" } ], "pmid": "" }, { "name": "negative regulation of canonical NF-kappaB signal transduction", "id": "GO:0043124", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0043124", "evidence": [ { "database": "UniProtKB", "id": "F1N7X6", "url": "https://www.uniprot.org/uniprotkb/F1N7X6" } ], "pmid": "" }, { "name": "mast cell activation", "id": "GO:0045576", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0045576", "evidence": [ { "database": "UniProtKB", "id": "F1N7X6", "url": "https://www.uniprot.org/uniprotkb/F1N7X6" } ], "pmid": "" }, { "name": "T cell differentiation", "id": "GO:0030217", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030217", "evidence": [ { "database": "UniProtKB", "id": "F1N7X6", "url": "https://www.uniprot.org/uniprotkb/F1N7X6" } ], "pmid": "" }, { "name": "positive regulation of T cell differentiation", "id": "GO:0045582", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0045582", "evidence": [ { "database": "UniProtKB", "id": "F1N7X6", "url": "https://www.uniprot.org/uniprotkb/F1N7X6" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "homologset.oma", "label": "OMA Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], 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"database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1N7X7/entry#names_and_taxonomy" } ] }, { "name": "Golgi-associated RAB2 interactor protein 3", "type": "synonym", "evidence": [ { "id": "XP_002689385", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_002689385" } ] } ], "function": [], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Bos taurus", "taxid": 9913, "evidence": [ { "database": "UniProtKB", "id": "F1N7X7", "url": "https://www.uniprot.org/uniprotkb/F1N7X7" } ], "common_name": "Bovine", "glygen_name": "Bovine", "reference_species": "Bos taurus [9913]" } ], "gene": [ { "name": "GARIN3", "url": "https://www.uniprot.org/uniprotkb/F1N7X7", "locus": { "chromosome": "7", "start_pos": 68850413, "end_pos": 68853077, "strand": "+", "evidence": [ { "database": "Ensembl Gene", "id": "ENSBTAG00000013450", "url": "https://www.ensembl.org/id/ENSBTAG00000013450" } ] } } ], "crossref": [ { "id": "F1N7X7", "url": "https://alphafold.ebi.ac.uk/entry/F1N7X7", "database": "AlphaFoldDB", "categories": [] }, { "id": "ENSBTAG00000013450", "url": "https://bgee.org/?page=gene&gene_id=ENSBTAG00000013450", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "540409", "url": "https://www.ncbi.nlm.nih.gov/gene/540409", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR022168", "url": "https://www.ebi.ac.uk/interpro/entry/IPR022168", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "bta:540409", "url": "https://www.genome.jp/dbget-bin/www_bget?bta:540409", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "TREDLFC", "url": "https://omabrowser.org/oma/group/TREDLFC/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "F1N7X7", "url": "https://www.orthodb.org/?gene=F1N7X7", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR22574", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR22574", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR22574:SF2", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR22574:SF2", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF12480", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF12480", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "XP_002689385", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_002689385", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "F1N7X7", "url": "https://www.uniprot.org/uniprotkb/F1N7X7", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "F1N7X7-1", "url": "https://www.uniprot.org/uniprotkb/F1N7X7-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MSSECLLPYYTANSYRSMDVFNTSMGDLQRQLYKGGEYDIFKYAPMFESDFIQISKKGEVIDVHNRVRMVTVGIASTSPILPLPDVMLLARPTKVCEEHVRHTRTTKGRGRKPAKTLELTRLLPLKFVKISIHDREKQQLRLKLATGRTFYLQLCPSSDAREDLFCYWEKLVYLLRPPVESCSSTPTLQTGDARILEGDKSLLTTELHRERDHDAVGLHKLGDVSGASSCAYVGGEGDYHVPHGSTTSLKSTEGGAAGTTSGLAVAGTTTSSGGGVAVAGVGAGSVGGAVSLAATRSTSTSQVSTTLAGAAAKGSRESGSGKAIVGAASISSEGTNLVLAGAASTSSTGMDSADSSMSVVFAGAVKTGKAAAVSAEGQVGAPLVSTLQSEGYMSERDGSQKVSHPRDETRKEKKERREKKDKSSSRKSSRHRRTGEGHHRTGGEKTRKSSSHRSVSGHGNKRDDKKEKGQSGTRGKGHSPHKSGSHSSSGKEGRTARKPGKSRSSTSSGTLNKRSSKISTFFRSFRVIPGSKPMVRHDREVDFVAKTVEKRNIEAKVEKAPVGEDVEIHGTVTSETMETIIIETKSV", "length": 587, "header": "tr|F1N7X7-1|F1N7X7_BOVIN Isoform 1 of Golgi associated RAB2B interactor family member 3 OS=Bos taurus OX=9913 GN=GARIN3 PE=3 SV=1 CANONICAL=F1N7X7-1" }, "isoforms": [ { "isoform_ac": "F1N7X7-1", "url": "https://www.uniprot.org/uniprotkb/F1N7X7/entry", "sequence": { "sequence": "MSSECLLPYYTANSYRSMDVFNTSMGDLQRQLYKGGEYDIFKYAPMFESDFIQISKKGEVIDVHNRVRMVTVGIASTSPILPLPDVMLLARPTKVCEEHVRHTRTTKGRGRKPAKTLELTRLLPLKFVKISIHDREKQQLRLKLATGRTFYLQLCPSSDAREDLFCYWEKLVYLLRPPVESCSSTPTLQTGDARILEGDKSLLTTELHRERDHDAVGLHKLGDVSGASSCAYVGGEGDYHVPHGSTTSLKSTEGGAAGTTSGLAVAGTTTSSGGGVAVAGVGAGSVGGAVSLAATRSTSTSQVSTTLAGAAAKGSRESGSGKAIVGAASISSEGTNLVLAGAASTSSTGMDSADSSMSVVFAGAVKTGKAAAVSAEGQVGAPLVSTLQSEGYMSERDGSQKVSHPRDETRKEKKERREKKDKSSSRKSSRHRRTGEGHHRTGGEKTRKSSSHRSVSGHGNKRDDKKEKGQSGTRGKGHSPHKSGSHSSSGKEGRTARKPGKSRSSTSSGTLNKRSSKISTFFRSFRVIPGSKPMVRHDREVDFVAKTVEKRNIEAKVEKAPVGEDVEIHGTVTSETMETIIIETKSV", "length": 587, "header": "tr|F1N7X7-1|F1N7X7_BOVIN Isoform 1 of Golgi associated RAB2B interactor family member 3 OS=Bos taurus OX=9913 GN=GARIN3 PE=3 SV=1 CANONICAL=F1N7X7-1" }, "locus": { "chromosome": "7", "start_pos": 68852982, "end_pos": 68850416, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000017892.5", "url": "https://www.ensembl.org/id/ENSBTAT00000017892.5" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000017892.4", "url": "https://www.ensembl.org/id/ENSBTAP00000017892.4" } ] } } ], "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "other", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 71, "start_aa": "Thr", "end_pos": 71, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr71", "evidence": [ { "id": "", "database": "GlyGen", "url": "https://data.glygen.org/" } ], "filter_code": "000000000000000010000.00000000001000.0.01000" } ], "phosphorylation": [], "glycation": [], "keywords": [ "glycoprotein", "glycoprotein_predicted" ], "publication": [], "pathway": [ { "id": "bta:540409", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?bta:540409", "resource": "KEGG Pathway" } ], "orthologs": [ { "uniprot_canonical_ac": "Q5STT6-1", "protein_name": "Golgi-associated RAB2B interactor protein 3", "gene_name": "Garin3", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MPGMKRTMSSECLLPYYTAHSYRSMGVFNTSMGNLQRQLYKGGEYDIFKYAPMFESDFIQISKRGEVIDVHNRVRMVTVCIASTSPVLPLPDVMLLARPAKVCEEHARRARFIKGKGCKPSKTLELTRLLPLKFVKISVHDHEKQQLRLKLATGRTFYLQLCPSSDAREDLFCYWEKLVYLLRPPMTNCISNSTLPTGETSVDTKSTLVSEIRGEGDQNSRPQSSPTVSEATSAAFAGGERTQPAAAAAVTPVSAKARAAGTAGAAAGTAGAAAGTAGPAAGPAAGTAGPAAGTAGAAAGTAGAAAGTAGATAGTAGATAGMAGATAGTAAETAGTAAETAGAARAAGGPMAAAVAAPSAGMTKAETATSPTSGVISLAATTTKPPGSGQVAAAMIGSAAKDQVGGESSKAMALAANITLENVDVALAGAANSISESPPAGGDASGSPDTGLNVAFAGSIKTKSPAEDKPEAPLVSTLQSEGYMCERDGSQKVSQTSSEAKEKRERREKDRTSSRKSSHHRRTGMSRHSSKDKSRKTSSYRSVSGKTREDKGKGHGRLRGKRHSSSHKSESRTGHKTRKNRSPAGLGSVSKRATKITSFFRSFLVRPTPKAGDTSCDRGGVDIVTKLVEKKQDIEAVMEKSKDSEFKDTVISETMEKIILETKSI", "length": 665 }, "evidence": [ { "id": "F1N7X7", "url": "https://omabrowser.org/oma/group/F1N7X7/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q66H38-1", "protein_name": "Golgi-associated RAB2B interactor protein 3", "gene_name": "Garin3", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MSSECLLPYYTAHSYRSMGVFNTSMGNLQRQLYKGGEYDIFKYAPMFESDFIQISKKGEVIDVHNRVRMVTVCIASTSPVLPLPDVMLLARPAKVCEEHARRARFIKGRGYKPSKTLELTRLLPLKFVKISIHDHEKQQLRLKLATGRTFYLQLCPSSDAREDLFCYWEKLVYLLRPPVNSCISNPSIPTADTSTETKSTLVSEIHGEGDRDSKFQTSQDVSEATSAAFAGGERTQPNIAAILTTGLAKARAAGAAAGTGAAGTAGTAGAAGATGAAGATGAAGSARAAGGAGSARAAGATGSARAAGATGSARAAGATGSARAAGGNTAAAVMTPLAGLARAGTPTSPVSGVISIAATTSKSPGSGQVATGLTGTASKDQERSESSKAMAVVANITTESVDVVLAGAASFTSESPSAEGDAYGSPDTGLNVAFAGSITTKGPAEDKPEAPLVSTLQSEGYMCERDGSQKVSHTSSETQKEKRERRESDRKGSRKSSHHQRTGASRHSSSKDKGRKTSSYRSVSGHGKTREDKKEKGRGSLRDQRHSSSYRSESRTGHKSRKNRPAASGGFVSKRATKIRSFFRAFLVRPTLKTENTSGERGGVDIVTKLVEKQDIETTVEKSKDLEFSDTMASESMEKIILETKPI", "length": 647 }, "evidence": [ { "id": "F1N7X7", "url": "https://omabrowser.org/oma/group/F1N7X7/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "Q8TC56-1", "protein_name": "Golgi-associated RAB2 interactor protein 3", "gene_name": "GARIN3", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MSNESCLPYYTAHSYSSMSAFKTSMGDLQRQLYNRGEYNIFKYAPMFESNFIQINKKGEVIDVHNRVRMVTVGIVCTSPILPLPDVMVLAQPTKICEQHVRWGRFAKGRGRRPVKTLELTRLLPLKFVKISIHDHEKQQLRLKLATGRTFYLQLCPSSDTREDLFCYWEKLVYLLRPPVESYCSTPTLLSGDAPPEDNKSLVAAELHREGDQSETGLYKPCDVSAATSSAYAGGEGIQHASHGTASAASPSTSTPGAAEGGAARTAGGMAVAGTATGPRTDVAIAGAAMSPATGAMSIATTKSAGPGQVTTALAGAAIKNPGENESSKSMAGAANISSEGISLALVGAASTSLEGTSTSMAGAASLSQDSSLSAAFAGSITTSKCAAERTEGPAVGPLISTLQSEGYMSERDGSQKVSQPSAEVWNENKERREKKDRHPSRKSSHHRKAGESHRRRAGDKNQKASSHRSASGHKNTRDDKKEKGYSNVRGKRHGSSRKSSTHSSTKKESRTTQELGKNQSASSTGALQKKASKISSFLRSLRATPGSKTRVTSHDREVDIVAKMVEKQNIEAKVEKAQGGQELEMISGTMTSEKTEMIVFETKSI", "length": 605 }, "evidence": [ { "id": "F1N7X7", "url": "https://omabrowser.org/oma/group/F1N7X7/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" } ], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 2, "go_terms": [ { "name": "sperm head", "id": "GO:0061827", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0061827", "evidence": [ { "database": "UniProtKB", "id": "F1N7X7", "url": "https://www.uniprot.org/uniprotkb/F1N7X7" } ], "pmid": "" }, { "name": "Golgi apparatus", "id": "GO:0005794", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005794", "evidence": [ { "database": "UniProtKB", "id": "F1N7X7", "url": "https://www.uniprot.org/uniprotkb/F1N7X7" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 22, "end_pos": 24, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [ { "pdb_id": "AF-F1N7X7-F1", "pdb_chain": "global", "start_pos": 1, "end_pos": 587, "overlap": "1.0", "method": "AlphaFold", "type": "alphafold", "resolution": -1.0, "url": "https://data.glygen.org/ln2downloads/pdb/current/AF-F1N7X7-F1.pdb", "url_external": "https://alphafold.ebi.ac.uk/entry/F1N7X7" } ], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "F1N7X7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1N7X7" }, { "id": "PF12480", "database": "Pfam", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF12480" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "Golgi associated RAB2 interactor protein-like Rab2B-binding", "eco_id": "ECO_0000259", "start_pos": 116, "end_pos": 185, "start_aa": "Thr", "end_aa": "Thr", "glycosite_overlap": [] } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "homologset.oma", "label": "OMA Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [ 71 ], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 22, "end_pos": 24 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 1 }, { "field": "total_sites", "count": 1 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 1 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "exact_sites", "count": 1 }, { "field": "exact_o_linked_sites", "count": 1 }, { "field": "fuzzy_sites", "count": 0 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_pos", "start_aa", "end_pos", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 1 }, { "field": "total_sites", "count": 1 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 1 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "exact_sites", "count": 1 }, { "field": "exact_o_linked_sites", "count": 1 }, { "field": "fuzzy_sites", "count": 0 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_pos", "start_aa", "end_pos", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ], "tool_support": { "graph_view": "yes" } }, { "uniprot_canonical_ac": "F1N7Z5-1", "uniprot_ac": "F1N7Z5", "uniprot_id": "F1N7Z5_BOVIN", "mass": { "chemical_mass": 39257.0, "monoisotopic_mass": 39257.0 }, "refseq": { "ac": "XP_024842417", "name": "protein TBATA isoform X5", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_024842417" }, "gene_names": [ { "name": "TBATA", "type": "recommended", "evidence": [ { "id": "F1N7Z5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1N7Z5" } ] }, { "name": "C28H10orf27", "type": "synonym", "evidence": [ { "id": "XP_024842417", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_024842417" } ] }, { "name": "SPATIAL", "type": "synonym", "evidence": [ { "id": "XP_024842417", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_024842417" } ] }, { "name": "TBATA", "type": "synonym", "evidence": [ { "id": "XP_024842417", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_024842417" } ] } ], "protein_names": [ { "name": "Thymus, brain and testes associated", "type": "synonym", "evidence": [ { "id": "F1N7Z5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1N7Z5/entry#names_and_taxonomy" } ] }, { "name": "protein TBATA isoform X5", "type": "synonym", "evidence": [ { "id": "XP_024842417", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_024842417" } ] } ], "function": [], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Bos taurus", "taxid": 9913, "evidence": [ { "database": "UniProtKB", "id": "F1N7Z5", "url": "https://www.uniprot.org/uniprotkb/F1N7Z5" } ], "common_name": "Bovine", "glygen_name": "Bovine", "reference_species": "Bos taurus [9913]" } ], "gene": [ { "name": "TBATA", "url": "https://www.uniprot.org/uniprotkb/F1N7Z5", "locus": { "chromosome": "28", "start_pos": 26937388, "end_pos": 26951865, "strand": "+", "evidence": [ { "database": "Ensembl Gene", "id": "ENSBTAG00000021180", "url": "https://www.ensembl.org/id/ENSBTAG00000021180" } ] } } ], "crossref": [ { "id": "F1N7Z5", "url": "https://alphafold.ebi.ac.uk/entry/F1N7Z5", "database": "AlphaFoldDB", "categories": [] }, { "id": "ENSBTAG00000021180", "url": "https://bgee.org/?page=gene&gene_id=ENSBTAG00000021180", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "515913", "url": "https://www.ncbi.nlm.nih.gov/gene/515913", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR037394", "url": "https://www.ebi.ac.uk/interpro/entry/IPR037394", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "F1N7Z5", "url": "https://www.orthodb.org/?gene=F1N7Z5", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR33772", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR33772", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR33772:SF3", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR33772:SF3", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF15256", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF15256", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "XP_024842417", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_024842417", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "F1N7Z5", "url": "https://www.uniprot.org/uniprotkb/F1N7Z5", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "F1N7Z5-1", "url": "https://www.uniprot.org/uniprotkb/F1N7Z5-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MATEVRAQLAERSLPSPKGELKLEKKSGCQPRSHGDSGPQKELMIPGIVDFKLIREAVRTSKPQTPSAYRFGRLSHHSFFSRHHPQPQHVTHIQDLTGKPVCVVRDELSLATSPQATLLSRYLIRMPTISVPVGDPQSNRDPRLYSEAWKKELKDLASRVAIFTKESELKSKEQKEEPQREQGAKYSAETGRLIPASTWAMARRHSHQGRNQPASRDGGDQTFVLQDQELLILELLSQILQTDSLNAIQFWLLYAPAKEKDMALGLLQTAVAQLLPQPLVPIPAEKLLNQLLEVQDSLQERHQLPYSQSPKKMKTPPLSKSEKPENIGKAQVLRVHSSQNPEEKAAKAEG", "length": 350, "header": "tr|F1N7Z5-1|F1N7Z5_BOVIN Isoform 1 of Thymus, brain and testes associated OS=Bos taurus OX=9913 GN=TBATA PE=4 SV=3 CANONICAL=F1N7Z5-1" }, "isoforms": [ { "isoform_ac": "F1N7Z5-1", "url": "https://www.uniprot.org/uniprotkb/F1N7Z5/entry", "sequence": { "sequence": "MATEVRAQLAERSLPSPKGELKLEKKSGCQPRSHGDSGPQKELMIPGIVDFKLIREAVRTSKPQTPSAYRFGRLSHHSFFSRHHPQPQHVTHIQDLTGKPVCVVRDELSLATSPQATLLSRYLIRMPTISVPVGDPQSNRDPRLYSEAWKKELKDLASRVAIFTKESELKSKEQKEEPQREQGAKYSAETGRLIPASTWAMARRHSHQGRNQPASRDGGDQTFVLQDQELLILELLSQILQTDSLNAIQFWLLYAPAKEKDMALGLLQTAVAQLLPQPLVPIPAEKLLNQLLEVQDSLQERHQLPYSQSPKKMKTPPLSKSEKPENIGKAQVLRVHSSQNPEEKAAKAEG", "length": 350, "header": "tr|F1N7Z5-1|F1N7Z5_BOVIN Isoform 1 of Thymus, brain and testes associated OS=Bos taurus OX=9913 GN=TBATA PE=4 SV=3 CANONICAL=F1N7Z5-1" }, "locus": { "chromosome": "28", "start_pos": 26949864, "end_pos": 26937533, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000036655.5", "url": "https://www.ensembl.org/id/ENSBTAT00000036655.5" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000036511.4", "url": "https://www.ensembl.org/id/ENSBTAP00000036511.4" } ] } } ], "glycosylation": [], "phosphorylation": [], 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} } ], "crossref": [ { "id": "F6PSM0", "url": "https://alphafold.ebi.ac.uk/entry/F6PSM0", "database": "AlphaFoldDB", "categories": [] }, { "id": "cd23014", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd23014", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "cd23274", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd23274", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "IPR006796", "url": "https://www.ebi.ac.uk/interpro/entry/IPR006796", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR039863", "url": "https://www.ebi.ac.uk/interpro/entry/IPR039863", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR047300", "url": "https://www.ebi.ac.uk/interpro/entry/IPR047300", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR047301", "url": "https://www.ebi.ac.uk/interpro/entry/IPR047301", "database": 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"MPGGNGMRRRGQLPAGPCAVAEASLGWEVAAPGPANGGGLGRSPSLGAGTGGASAAGSPGYQRCRIPAELLAPAVRPPSSSSSAASRQTRARPEVQTRAQRSPVGAAAEMRRLGGTLLYLLLAAAVPTAPAPAPTVTSASIEPGPALSYPQEEATLNEMFREVEELMEDTQYKLRSAVEEMEAEEAAAKTSSEVTLAHLPPSYHNETNTETKVGNNTIHVHREIHKITNNRTGQMVFSETVITSMGDEEGKRSHECIIDEDCGPSRYCQFSSFEYSCQPCRDQQTLCTRDSECCGDQLCVWGRCTKTSTAGSNGTICDNQRDCQPGLCCAFQRGLLFPVCTPLPVEGELCHDPASRLLDLITWELEPDGALDRCPCASGLLCQPHSHSLVYVCKPTFVGGRDEDGESLVPREAPDEYEDGGFMEEVRRELENLERSLSVEMALGEPGAASELLEGEEI", "length": 458, "header": "tr|F6PSM0-1|F6PSM0_BOVIN Isoform 1 of Dickkopf-related protein 3 OS=Bos taurus OX=9913 GN=DKK3 PE=3 SV=1 CANONICAL=F6PSM0-1" }, "locus": { "chromosome": "15", "start_pos": 40733905, "end_pos": 40685135, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000005599.7", "url": "https://www.ensembl.org/id/ENSBTAT00000005599.7" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000005599.5", "url": "https://www.ensembl.org/id/ENSBTAP00000005599.5" } ] } } ], "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "other", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 135, "start_aa": "Thr", "end_pos": 135, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr135", "evidence": [ { "id": "", "database": "GlyGen", "url": "https://data.glygen.org/" } ], "filter_code": "000000000000000010000.00000000001000.0.01000" } ], "phosphorylation": [], "glycation": [], "keywords": [ "glycoprotein", "glycoprotein_predicted" ], "publication": [], "pathway": [], "orthologs": [], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 1, "go_terms": [ { "name": "extracellular region", "id": "GO:0005576", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005576", "evidence": [ { "database": "UniProtKB", "id": "F6PSM0", "url": "https://www.uniprot.org/uniprotkb/F6PSM0" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 6, "go_terms": [ { "name": "negative regulation of canonical Wnt signaling pathway", "id": "GO:0090090", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0090090", "evidence": [ { "database": "UniProtKB", "id": "F6PSM0", "url": "https://www.uniprot.org/uniprotkb/F6PSM0" } ], "pmid": "" }, { "name": "negative regulation of DNA-templated transcription", "id": "GO:0045892", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0045892", "evidence": [ { "database": "UniProtKB", "id": "F6PSM0", "url": "https://www.uniprot.org/uniprotkb/F6PSM0" } ], "pmid": "" }, { "name": "Wnt signaling pathway", "id": "GO:0016055", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016055", "evidence": [ { "database": "UniProtKB", "id": "F6PSM0", "url": "https://www.uniprot.org/uniprotkb/F6PSM0" } ], "pmid": "" }, { "name": "adrenal gland development", "id": "GO:0030325", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030325", "evidence": [ { "database": "UniProtKB", "id": "F6PSM0", "url": "https://www.uniprot.org/uniprotkb/F6PSM0" } ], "pmid": "" }, { "name": "negative regulation of aldosterone biosynthetic process", "id": "GO:0032348", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0032348", "evidence": [ { "database": "UniProtKB", "id": "F6PSM0", "url": "https://www.uniprot.org/uniprotkb/F6PSM0" } ], "pmid": "" }, { "name": "negative regulation of cortisol biosynthetic process", "id": "GO:2000065", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:2000065", "evidence": [ { "database": "UniProtKB", "id": "F6PSM0", "url": "https://www.uniprot.org/uniprotkb/F6PSM0" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 205, "end_pos": 207, "annotation": "n_glycosylation_sequon" }, { "start_pos": 215, "end_pos": 217, "annotation": "n_glycosylation_sequon" }, { "start_pos": 230, "end_pos": 232, "annotation": "n_glycosylation_sequon" }, { "start_pos": 313, "end_pos": 315, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "F6PSM0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F6PSM0" }, { "id": "PF04706", "database": "Pfam", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF04706" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "Dickkopf N-terminal cysteine-rich", "eco_id": "ECO_0000259", "start_pos": 255, "end_pos": 305, "start_aa": "Glu", "end_aa": "Thr", "glycosite_overlap": [] } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [ 135 ], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 205, "end_pos": 207 }, { "start_pos": 215, "end_pos": 217 }, { "start_pos": 230, "end_pos": 232 }, { "start_pos": 313, "end_pos": 315 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 1 }, { "field": "total_sites", "count": 1 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 1 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "exact_sites", "count": 1 }, { "field": "exact_o_linked_sites", "count": 1 }, { "field": "fuzzy_sites", "count": 0 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_pos", "start_aa", "end_pos", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { 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"sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ], "tool_support": { "graph_view": "yes" } }, { "uniprot_canonical_ac": "F6PSV7-1", "uniprot_ac": "F6PSV7", "uniprot_id": "F6PSV7_BOVIN", "mass": { "chemical_mass": 49598.0, "monoisotopic_mass": 49598.0 }, "refseq": {}, "gene_names": [ { "name": "SERPINA14", "type": "recommended", "evidence": [ { "id": "F6PSV7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F6PSV7" } ] } ], "protein_names": [ { "name": "Serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 14", "type": "synonym", "evidence": [ { "id": "F6PSV7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F6PSV7/entry#names_and_taxonomy" } ] } ], "function": [], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Bos taurus", "taxid": 9913, "evidence": [ { "database": "UniProtKB", "id": "F6PSV7", "url": "https://www.uniprot.org/uniprotkb/F6PSV7" } ], "common_name": "Bovine", "glygen_name": "Bovine", "reference_species": "Bos taurus [9913]" } ], "gene": [ { "name": "SERPINA14", "url": "https://www.uniprot.org/uniprotkb/F6PSV7", "locus": {} } ], "crossref": [ { "id": "F6PSV7", "url": "https://alphafold.ebi.ac.uk/entry/F6PSV7", "database": "AlphaFoldDB", "categories": [] }, { "id": "cd19559", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd19559", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "IPR000215", "url": "https://www.ebi.ac.uk/interpro/entry/IPR000215", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR023795", "url": "https://www.ebi.ac.uk/interpro/entry/IPR023795", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR023796", "url": "https://www.ebi.ac.uk/interpro/entry/IPR023796", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR036186", "url": "https://www.ebi.ac.uk/interpro/entry/IPR036186", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR042178", "url": "https://www.ebi.ac.uk/interpro/entry/IPR042178", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR042185", "url": "https://www.ebi.ac.uk/interpro/entry/IPR042185", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "PTHR11461", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR11461", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR11461:SF164", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR11461:SF164", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00079", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00079", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "F6PSV7", "url": "https://www.uniprot.org/uniprotkb/F6PSV7", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "F6PSV7-1", "url": "https://www.uniprot.org/uniprotkb/F6PSV7-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MSHGRMNLALSLVFILCGLFNSIFCEKQQHSQKHMNLVLLKKISALSQKMEAHPKDFAQELFKALIIEDPRKNIIFSPMAMTTTLATLSLGIKSTMRTHHPEDLKLEPKLLDVHKYLQPLVHVGRELVKQKVLKHQHILFINRKMMVNQMLLQQISKLQGMDIQMIDFTDIEKAKKTISHHVAEKTHTKITNLITDLNPETILCLVNHIFFKGILKRAFQPKLTQKEVFFVNDQTKVQVDMMRKTERMLYSRSEELHATMVKMPCKGNVSLTLMLPDAGQFDTDLKKMTAKRAKLQKISDFRLVRLILPKLKISFKINFKHLLPKIDPKHILTATAISQAITSKAPLPNLEALHQAEIELSEHALTVDTAIHTDNLLKVPMKAKEVPAVVKVPMNTKEVPVVVKVNRPFLLFVEDEKTQRDLFVGKVLNPQVE", "length": 433, "header": "tr|F6PSV7-1|F6PSV7_BOVIN Isoform 1 of Serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 14 OS=Bos taurus OX=9913 GN=SERPINA14 PE=3 SV=1 CANONICAL=F6PSV7-1" }, "isoforms": [ { "isoform_ac": "F6PSV7-1", "url": "https://www.uniprot.org/uniprotkb/F6PSV7/entry", "sequence": { "sequence": "MSHGRMNLALSLVFILCGLFNSIFCEKQQHSQKHMNLVLLKKISALSQKMEAHPKDFAQELFKALIIEDPRKNIIFSPMAMTTTLATLSLGIKSTMRTHHPEDLKLEPKLLDVHKYLQPLVHVGRELVKQKVLKHQHILFINRKMMVNQMLLQQISKLQGMDIQMIDFTDIEKAKKTISHHVAEKTHTKITNLITDLNPETILCLVNHIFFKGILKRAFQPKLTQKEVFFVNDQTKVQVDMMRKTERMLYSRSEELHATMVKMPCKGNVSLTLMLPDAGQFDTDLKKMTAKRAKLQKISDFRLVRLILPKLKISFKINFKHLLPKIDPKHILTATAISQAITSKAPLPNLEALHQAEIELSEHALTVDTAIHTDNLLKVPMKAKEVPAVVKVPMNTKEVPVVVKVNRPFLLFVEDEKTQRDLFVGKVLNPQVE", "length": 433, "header": "tr|F6PSV7-1|F6PSV7_BOVIN Isoform 1 of Serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 14 OS=Bos taurus OX=9913 GN=SERPINA14 PE=3 SV=1 CANONICAL=F6PSV7-1" }, "locus": { "chromosome": "21", "start_pos": 59172274, "end_pos": 59164289, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000009718.7", "url": "https://www.ensembl.org/id/ENSBTAT00000009718.7" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000009718.6", "url": "https://www.ensembl.org/id/ENSBTAP00000009718.6" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [], "orthologs": [], "go_annotation": { "categories": [ { "name": "Molecular Function", "total": 1, "go_terms": [ { "name": "serine-type endopeptidase inhibitor activity", "id": "GO:0004867", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0004867", "evidence": [ { "database": "UniProtKB", "id": "F6PSV7", "url": "https://www.uniprot.org/uniprotkb/F6PSV7" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 1, "go_terms": [ { "name": "extracellular space", "id": "GO:0005615", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005615", "evidence": [ { "database": "UniProtKB", "id": "F6PSV7", "url": "https://www.uniprot.org/uniprotkb/F6PSV7" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 268, "end_pos": 270, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], 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"id": "IPR004181", "url": "https://www.ebi.ac.uk/interpro/entry/IPR004181", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR013083", "url": "https://www.ebi.ac.uk/interpro/entry/IPR013083", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR023321", "url": "https://www.ebi.ac.uk/interpro/entry/IPR023321", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR036361", "url": "https://www.ebi.ac.uk/interpro/entry/IPR036361", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR038654", "url": "https://www.ebi.ac.uk/interpro/entry/IPR038654", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "A0A3Q1LMC0", "url": "https://www.orthodb.org/?gene=A0A3Q1LMC0", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR10782", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR10782", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR10782:SF10", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR10782:SF10", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF02037", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF02037", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF02891", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF02891", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF14324", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF14324", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "A0A3Q1LMC0", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1LMC0", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A3Q1LMC0-1", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1LMC0-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0ABI0P282", "url": 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"MAELGELKVPAPSPIPIWTEPGCTPSLGSDRDWHMVMSFRVSELQVLLGFAGRNKSGRKHELLAKALHLLKSSCAPSVQMKIKELYRRRFPRKTLGPSDLSLLSLPPGTPPVGSPGPLAPIPPALLAPGTLLGPKREVDMHPPLPQPVHPDVTMKPLPFYEIYGELIRPTTLASTSSQRFEEAHFTFALTPQQVQQILTSREVLPGAKCDYTIQVQLRFCLCETSCPQEDYFPPNLFVKVNGKLCPLPGYLPPTKNGAEPKRPSRPINITPLARLSATVPNTIVVNWSSEFGRNYSLSVYLVRQLTAGTLLQKLRAKGIRNPDHSRALIKEKLTADPDSEVATTSLRVSLMCPLGKMRLTVPCRALTCAHLQSFDAALYLQMNEKKPTWTCPVCDKKAPYESLIIDGLFMEILNSCSDCDEIQFMEDGSWCPMKPKKEASEVCPPPGYGLDGLQYSPVQEGNPSESKKKVEVIDLTVESSSDEEDLPPTKKHCPVTSAAIPALPGSKGVLTSGHQPSSVLRSPAMGTLGGDFLSSLPLHEYPPAFPLGADIQGLDLFSFLQTESQHYGPSVITSLDEQDALGHFFQYRGTPSHFLGPLTPTLGSSHRSATPAPPPGRVSSIVAPGGTLREGHGGPLPSGPSLTGCRSDIISLD", "length": 653, "header": "tr|F6PT61-1|F6PT61_BOVIN Isoform 1 of Protein inhibitor of activated STAT 3 OS=Bos taurus OX=9913 GN=PIAS3 PE=3 SV=1 CANONICAL=F6PT61-1" }, "isoforms": [ { "isoform_ac": "A0A3Q1LMC0-1", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1LMC0/entry", "sequence": { "sequence": "MAELGELKHMVMSFRVSELQVLLGFAGRNKSGRKHELLAKALHLLKSSCAPSVQMKIKELYRRRFPRKTLGPSDLSLLSLPPGTPPPVHPDVTMKPLPFYEIYGELIRPTTLASTSSQRFEEAHFTFALTPQQVQQILTSREVLPGAKCDYTIQVQLRFCLCETSCPQEDYFPPNLFVKVNGKLCPLPGYLPPTKNGAEPKRPSRPINITPLARLSATVPNTIVVNWSSEFGRNYSLSVYLVRQLTAGTLLQKLRAKGIRNPDHSRALIKEKLTADPDSEVATTSLRVSLMCPLGKMRLTVPCRALTCAHLQSFDAALYLQMNEKKPTWTCPVCDKKAPYESLIIDGLFMEILNSCSDCDEIQFMEDGSWCPMKPKKEASEVCPPPGYGLDGLQYSPVQEGNPSESKKKVEVIDLTVESSSDEEDLPPTKKHCPVTSAAIPALPGSKGVLTSGHQPSSVLRSPAMGTLGGDFLSSLPLHEYPPAFPLGADIQGLDLFSFLQTESQHYGPSVITSLDEQDALGHFFQYRGTPSHFLGPLTPTLGSSHRSATPAPPPGRVSSIVAPGGTLREGHGGPLPSGPSLTGCRSDIISLD", "length": 593, "header": "tr|A0A3Q1LMC0-1|A0A3Q1LMC0_BOVIN Computationally mapped isoform of Protein inhibitor of activated STAT 3 OS=Bos taurus OX=9913 GN=PIAS3 PE=3 SV=2 CANONICAL=F6PT61-1" }, "locus": { "chromosome": "3", "start_pos": 21514298, "end_pos": 21505887, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000085045.2", "url": 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mapped isoform of Protein inhibitor of activated STAT 3 OS=Bos taurus OX=9913 GN=PIAS3 PE=3 SV=1 CANONICAL=F6PT61-1" }, "locus": { "chromosome": "3", "start_pos": 21514298, "end_pos": 21507825, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000149645.1", "url": "https://www.ensembl.org/id/ENSBTAT00000149645.1" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000104737.1", "url": "https://www.ensembl.org/id/ENSBTAP00000104737.1" } ] } }, { "isoform_ac": "F6PT61-1", "url": "https://www.uniprot.org/uniprotkb/F6PT61/entry", "sequence": { "sequence": "MAELGELKVPAPSPIPIWTEPGCTPSLGSDRDWHMVMSFRVSELQVLLGFAGRNKSGRKHELLAKALHLLKSSCAPSVQMKIKELYRRRFPRKTLGPSDLSLLSLPPGTPPVGSPGPLAPIPPALLAPGTLLGPKREVDMHPPLPQPVHPDVTMKPLPFYEIYGELIRPTTLASTSSQRFEEAHFTFALTPQQVQQILTSREVLPGAKCDYTIQVQLRFCLCETSCPQEDYFPPNLFVKVNGKLCPLPGYLPPTKNGAEPKRPSRPINITPLARLSATVPNTIVVNWSSEFGRNYSLSVYLVRQLTAGTLLQKLRAKGIRNPDHSRALIKEKLTADPDSEVATTSLRVSLMCPLGKMRLTVPCRALTCAHLQSFDAALYLQMNEKKPTWTCPVCDKKAPYESLIIDGLFMEILNSCSDCDEIQFMEDGSWCPMKPKKEASEVCPPPGYGLDGLQYSPVQEGNPSESKKKVEVIDLTVESSSDEEDLPPTKKHCPVTSAAIPALPGSKGVLTSGHQPSSVLRSPAMGTLGGDFLSSLPLHEYPPAFPLGADIQGLDLFSFLQTESQHYGPSVITSLDEQDALGHFFQYRGTPSHFLGPLTPTLGSSHRSATPAPPPGRVSSIVAPGGTLREGHGGPLPSGPSLTGCRSDIISLD", "length": 653, "header": "tr|F6PT61-1|F6PT61_BOVIN Isoform 1 of Protein inhibitor of activated STAT 3 OS=Bos taurus OX=9913 GN=PIAS3 PE=3 SV=1 CANONICAL=F6PT61-1" }, "locus": { "chromosome": "3", "start_pos": 21514298, "end_pos": 21505887, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000028829.6", "url": "https://www.ensembl.org/id/ENSBTAT00000028829.6" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000028829.5", "url": "https://www.ensembl.org/id/ENSBTAP00000028829.5" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [], "orthologs": [], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 5, "go_terms": [ { "name": "glutamatergic synapse", "id": "GO:0098978", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0098978", "evidence": [ { "database": "UniProtKB", "id": "F6PT61", "url": "https://www.uniprot.org/uniprotkb/F6PT61" } ], "pmid": "" }, { "name": "nuclear speck", "id": "GO:0016607", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016607", "evidence": [ { "database": "UniProtKB", "id": "F6PT61", "url": "https://www.uniprot.org/uniprotkb/F6PT61" } ], "pmid": "" }, { "name": "presynaptic cytosol", "id": "GO:0099523", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0099523", "evidence": [ { "database": "UniProtKB", "id": "F6PT61", "url": "https://www.uniprot.org/uniprotkb/F6PT61" } ], "pmid": "" }, { "name": "postsynaptic cytosol", "id": "GO:0099524", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0099524", "evidence": [ { "database": "UniProtKB", "id": "F6PT61", "url": "https://www.uniprot.org/uniprotkb/F6PT61" } ], "pmid": "" }, { "name": "nucleus", "id": "GO:0005634", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005634", "evidence": [ { "database": "UniProtKB", "id": "F6PT61", "url": "https://www.uniprot.org/uniprotkb/F6PT61" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 5, "go_terms": [ { "name": "DNA-templated transcription", "id": "GO:0006351", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006351", "evidence": [ { "database": "UniProtKB", "id": "F6PT61", "url": "https://www.uniprot.org/uniprotkb/F6PT61" } ], "pmid": "" }, { "name": "positive regulation of protein sumoylation", "id": "GO:0033235", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0033235", "evidence": [ { "database": "UniProtKB", "id": "F6PT61", "url": "https://www.uniprot.org/uniprotkb/F6PT61" } ], "pmid": "" }, { "name": "negative regulation of protein sumoylation", "id": "GO:0033234", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0033234", "evidence": [ { "database": "UniProtKB", "id": "F6PT61", "url": "https://www.uniprot.org/uniprotkb/F6PT61" } ], "pmid": "" }, { "name": "protein sumoylation", "id": "GO:0016925", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016925", "evidence": [ { "database": "UniProtKB", "id": "F6PT61", "url": "https://www.uniprot.org/uniprotkb/F6PT61" } ], "pmid": "" }, { "name": "regulation of macromolecule metabolic process", "id": "GO:0060255", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0060255", "evidence": [ { "database": "UniProtKB", "id": "F6PT61", "url": "https://www.uniprot.org/uniprotkb/F6PT61" } ], "pmid": "" } ] }, { "name": "Molecular Function", "total": 3, "go_terms": [ { "name": "zinc ion binding", "id": "GO:0008270", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008270", "evidence": [ { "database": "UniProtKB", "id": "F6PT61", "url": "https://www.uniprot.org/uniprotkb/F6PT61" } ], "pmid": "" }, { "name": "SUMO transferase activity", "id": "GO:0019789", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0019789", "evidence": [ { "database": "UniProtKB", "id": "F6PT61", "url": "https://www.uniprot.org/uniprotkb/F6PT61" } ], "pmid": "" }, { "name": "transferase activity", "id": "GO:0016740", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016740", "evidence": [ { "database": "UniProtKB", "id": "F6PT61", "url": "https://www.uniprot.org/uniprotkb/F6PT61" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 268, "end_pos": 270, "annotation": "n_glycosylation_sequon" }, { "start_pos": 286, "end_pos": 288, "annotation": "n_glycosylation_sequon" }, { "start_pos": 294, "end_pos": 296, "annotation": "n_glycosylation_sequon" }, { "start_pos": 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"categories": [ "Protein Classification" ] }, { "id": "IPR018039", "url": "https://www.ebi.ac.uk/interpro/entry/IPR018039", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR032444", "url": "https://www.ebi.ac.uk/interpro/entry/IPR032444", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR039008", "url": "https://www.ebi.ac.uk/interpro/entry/IPR039008", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "PTHR45616", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR45616", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR45616:SF12", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR45616:SF12", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00038", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00038", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": 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"evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000009403.5", "url": "https://www.ensembl.org/id/ENSBTAT00000009403.5" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000009403.4", "url": "https://www.ensembl.org/id/ENSBTAP00000009403.4" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [], "orthologs": [], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 1, "go_terms": [ { "name": "keratin filament", "id": "GO:0045095", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0045095", "evidence": [ { "database": "UniProtKB", "id": "F6PVE3", "url": "https://www.uniprot.org/uniprotkb/F6PVE3" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 311, "end_pos": 313, "annotation": "n_glycosylation_sequon" }, { "start_pos": 449, "end_pos": 451, "annotation": "n_glycosylation_sequon" }, { "start_pos": 96, "end_pos": 98, "annotation": 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"publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ], "tool_support": { "graph_view": "yes" } }, { "uniprot_canonical_ac": "F6PWA6-1", "uniprot_ac": "F6PWA6", "uniprot_id": "F6PWA6_BOVIN", "mass": { "chemical_mass": 57343.0, "monoisotopic_mass": 57343.0 }, "refseq": {}, "gene_names": [ { "name": "NHERF4", "type": "recommended", "evidence": [ { "id": "F6PWA6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F6PWA6" } ] } ], "protein_names": [ { "name": "Na(+)/H(+) exchange regulatory cofactor NHE-RF4", "type": "recommended", "evidence": [ { "id": "F6PWA6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F6PWA6/entry#names_and_taxonomy" } ] }, { "name": "Natrium-phosphate cotransporter IIa C-terminal-associated protein 2", "type": "synonym", "evidence": [ { "id": "F6PWA6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F6PWA6/entry#names_and_taxonomy" } ] }, { "name": "PDZ domain-containing 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"F6PWA6", "url": "https://alphafold.ebi.ac.uk/entry/F6PWA6", "database": "AlphaFoldDB", "categories": [] }, { "id": "cd06768", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd06768", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "IPR001478", "url": "https://www.ebi.ac.uk/interpro/entry/IPR001478", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR036034", "url": "https://www.ebi.ac.uk/interpro/entry/IPR036034", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR051067", "url": "https://www.ebi.ac.uk/interpro/entry/IPR051067", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "PTHR14191", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR14191", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR14191:SF20", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR14191:SF20", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00595", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00595", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "F6PWA6", "url": "https://www.uniprot.org/uniprotkb/F6PWA6", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "F6PWA6-1", "url": "https://www.uniprot.org/uniprotkb/F6PWA6-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MEAAAVLSVNDHGSGVSEGRLPFIPSPLLCLADLQDTATLALKFEFNPKLGIDNPVLSLAEDYNPSDIWSLERPRFYLLNKEEGRTFGFHLQQQLGRAGHVVCRVEPGSSAQRQGLREGDWILGVNNHVVEHEDYLMVIRRIRASGPRVLLTVLAQHVHEVARAQRGNNTHLCPPLGQGVRPRLCHVVKDEGGFGFSVTQGHRGPFWLVLSPGGAAERAGVPPGARLLEVNGVSVEKLTHNQLNRKLWQSGKQVTLLVAGPEVEEQCRQLGMPLAAPLAEGWALPTKPRCLHLEKGPQGFGFVLREEKGLDGRLGQFLWEVDPGLPAEKAGMQAGDRLVAVAGESVEGLGHEETVSKIRAQGSCVSLIVVDPKADRFFSMVRLSPLLFLESTEAPDSPWGSGLASVVETKNPLVKDATVAAVPCNFRQCFLYPGPGGGYGFRLSCVASRPGLFISQVTLGGSAAQAGLQTGDMILEVNGYPMGGEKDQERLQQLAEAKPPLCLKLAAQSQQGLEAWIPPGSREDGVLASDLL", "length": 532, "header": "tr|F6PWA6-1|F6PWA6_BOVIN Isoform 1 of Na(+)/H(+) exchange regulatory cofactor NHE-RF4 OS=Bos taurus OX=9913 GN=NHERF4 PE=4 SV=1 CANONICAL=F6PWA6-1" }, "isoforms": [ { "isoform_ac": "F6PWA6-1", "url": "https://www.uniprot.org/uniprotkb/F6PWA6/entry", "sequence": { "sequence": "MEAAAVLSVNDHGSGVSEGRLPFIPSPLLCLADLQDTATLALKFEFNPKLGIDNPVLSLAEDYNPSDIWSLERPRFYLLNKEEGRTFGFHLQQQLGRAGHVVCRVEPGSSAQRQGLREGDWILGVNNHVVEHEDYLMVIRRIRASGPRVLLTVLAQHVHEVARAQRGNNTHLCPPLGQGVRPRLCHVVKDEGGFGFSVTQGHRGPFWLVLSPGGAAERAGVPPGARLLEVNGVSVEKLTHNQLNRKLWQSGKQVTLLVAGPEVEEQCRQLGMPLAAPLAEGWALPTKPRCLHLEKGPQGFGFVLREEKGLDGRLGQFLWEVDPGLPAEKAGMQAGDRLVAVAGESVEGLGHEETVSKIRAQGSCVSLIVVDPKADRFFSMVRLSPLLFLESTEAPDSPWGSGLASVVETKNPLVKDATVAAVPCNFRQCFLYPGPGGGYGFRLSCVASRPGLFISQVTLGGSAAQAGLQTGDMILEVNGYPMGGEKDQERLQQLAEAKPPLCLKLAAQSQQGLEAWIPPGSREDGVLASDLL", "length": 532, "header": "tr|F6PWA6-1|F6PWA6_BOVIN Isoform 1 of Na(+)/H(+) exchange regulatory cofactor NHE-RF4 OS=Bos taurus OX=9913 GN=NHERF4 PE=4 SV=1 CANONICAL=F6PWA6-1" }, "locus": { "chromosome": "15", "start_pos": 29773727, "end_pos": 29770018, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000023657.5", "url": "https://www.ensembl.org/id/ENSBTAT00000023657.5" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000023657.4", "url": "https://www.ensembl.org/id/ENSBTAP00000023657.4" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [], "orthologs": [], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 4, "go_terms": [ { "name": "cytoplasm", "id": "GO:0005737", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005737", "evidence": [ { "database": "UniProtKB", "id": "F6PWA6", "url": "https://www.uniprot.org/uniprotkb/F6PWA6" } ], "pmid": "" }, { "name": "plasma membrane", "id": "GO:0005886", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005886", "evidence": [ { "database": "UniProtKB", "id": "F6PWA6", "url": "https://www.uniprot.org/uniprotkb/F6PWA6" } ], "pmid": "" }, { "name": "brush border", "id": "GO:0005903", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005903", "evidence": [ { "database": "UniProtKB", "id": "F6PWA6", "url": "https://www.uniprot.org/uniprotkb/F6PWA6" } ], "pmid": "" }, { "name": "apical junction complex", "id": "GO:0043296", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0043296", "evidence": [ { "database": "UniProtKB", "id": "F6PWA6", "url": "https://www.uniprot.org/uniprotkb/F6PWA6" } ], "pmid": "" } ] }, { "name": "Molecular Function", "total": 2, "go_terms": [ { "name": "ubiquitin-specific protease binding", "id": "GO:1990381", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:1990381", "evidence": [ { "database": "UniProtKB", "id": "F6PWA6", "url": "https://www.uniprot.org/uniprotkb/F6PWA6" } ], "pmid": "" }, { "name": "guanylate cyclase inhibitor activity", "id": "GO:0030251", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030251", "evidence": [ { "database": "UniProtKB", "id": "F6PWA6", "url": "https://www.uniprot.org/uniprotkb/F6PWA6" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 168, "end_pos": 170, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "F6PWA6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F6PWA6" }, { "id": "PS50106", "database": "PROSITE", "url": "https://prosite.expasy.org/PS50106" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "PDZ", "eco_id": "ECO_0000259", "start_pos": 75, "end_pos": 157, "start_aa": "Arg", "end_aa": "His", "glycosite_overlap": [] } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 168, "end_pos": 170 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ], "tool_support": { "graph_view": "yes" } }, { "uniprot_canonical_ac": "F6PWU2-1", "uniprot_ac": "F6PWU2", "uniprot_id": "F6PWU2_BOVIN", "mass": { "chemical_mass": 22066.0, "monoisotopic_mass": 22066.0 }, "refseq": { "ac": "XP_005221461", "name": "transcription factor BTF3 isoform X1", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_005221461" }, "gene_names": [ { "name": "BTF3", "type": "recommended", "evidence": [ { "id": "F6PWU2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F6PWU2" } ] }, { "name": "BTF3", "type": "synonym", "evidence": [ { "id": "XP_005221461", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_005221461" } ] } ], "protein_names": [ { "name": "Transcription factor BTF3", "type": "recommended", "evidence": [ { "id": "F6PWU2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F6PWU2/entry#names_and_taxonomy" } ] }, { "name": "transcription factor BTF3 isoform X1", "type": "synonym", "evidence": [ { "id": "XP_005221461", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_005221461" } ] } ], "function": [], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Bos taurus", "taxid": 9913, "evidence": [ { "database": "UniProtKB", "id": "F6PWU2", "url": "https://www.uniprot.org/uniprotkb/F6PWU2" } ], "common_name": "Bovine", "glygen_name": "Bovine", "reference_species": "Bos taurus [9913]" } ], "gene": [ { "name": "BTF3", "url": "https://www.uniprot.org/uniprotkb/F6PWU2", "locus": { "chromosome": "20", "start_pos": 8116737, "end_pos": 8123261, "strand": "+", "evidence": [ { "database": "Ensembl Gene", "id": "ENSBTAG00000010012", "url": "https://www.ensembl.org/id/ENSBTAG00000010012" } ] } } ], "crossref": [ { "id": "F6PWU2", "url": "https://alphafold.ebi.ac.uk/entry/F6PWU2", "database": "AlphaFoldDB", "categories": [] }, { "id": "cd22055", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd22055", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "281031", "url": "https://www.ncbi.nlm.nih.gov/gene/281031", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR002715", "url": "https://www.ebi.ac.uk/interpro/entry/IPR002715", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR038187", "url": "https://www.ebi.ac.uk/interpro/entry/IPR038187", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR039370", "url": "https://www.ebi.ac.uk/interpro/entry/IPR039370", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "PTHR10351", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR10351", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF01849", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF01849", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "XP_005221461", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_005221461", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "F6PWU2", "url": "https://www.uniprot.org/uniprotkb/F6PWU2", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "F6PWU2-1", "url": "https://www.uniprot.org/uniprotkb/F6PWU2-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MRRTGAPTQADSRGRGRARGGCPGGEAAASLPPPPGGTRGQEPQMKETIMNQEKLAKLQAQVRIGGKGTARRKKKVVHRTATADDKKLQFSLKKLGVNNISGIEEVNMFTNQGTVIHFNNPKVQASLAANTFTITGHAETKQLTEMLPSILNQLGADSLTSLRRLAEALPKQSVDGKAPLATGEEDDDEVPDLVENFDEASKNEAN", "length": 206, "header": "tr|F6PWU2-1|F6PWU2_BOVIN Isoform 1 of Transcription factor BTF3 OS=Bos taurus OX=9913 GN=BTF3 PE=3 SV=1 CANONICAL=F6PWU2-1" }, "isoforms": [ { "isoform_ac": "F6PWU2-1", "url": "https://www.uniprot.org/uniprotkb/F6PWU2/entry", "sequence": { "sequence": "MRRTGAPTQADSRGRGRARGGCPGGEAAASLPPPPGGTRGQEPQMKETIMNQEKLAKLQAQVRIGGKGTARRKKKVVHRTATADDKKLQFSLKKLGVNNISGIEEVNMFTNQGTVIHFNNPKVQASLAANTFTITGHAETKQLTEMLPSILNQLGADSLTSLRRLAEALPKQSVDGKAPLATGEEDDDEVPDLVENFDEASKNEAN", "length": 206, "header": "tr|F6PWU2-1|F6PWU2_BOVIN Isoform 1 of Transcription factor BTF3 OS=Bos taurus OX=9913 GN=BTF3 PE=3 SV=1 CANONICAL=F6PWU2-1" }, "locus": { "chromosome": "20", "start_pos": 8123062, "end_pos": 8116995, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000036839.4", "url": "https://www.ensembl.org/id/ENSBTAT00000036839.4" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000036691.3", "url": "https://www.ensembl.org/id/ENSBTAP00000036691.3" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [], "orthologs": [], "go_annotation": {}, "pro_annotation": [], "site_annotation": [ { "start_pos": 99, "end_pos": 101, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "F6PWU2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F6PWU2" }, { "id": "PS51151", "database": "PROSITE", "url": "https://prosite.expasy.org/PS51151" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "NAC-A/B", "eco_id": "ECO_0000259", "start_pos": 82, "end_pos": 147, "start_aa": "Thr", "end_aa": "Leu", "glycosite_overlap": [] } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 99, "end_pos": 101 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", 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"field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ], "tool_support": { "graph_view": "yes" } }, { "uniprot_canonical_ac": "F6PX95-1", "uniprot_ac": "F6PX95", "uniprot_id": "F6PX95_BOVIN", "mass": { "chemical_mass": 56725.0, "monoisotopic_mass": 56725.0 }, "refseq": {}, "gene_names": [ { "name": "ESS2", "type": 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"https://www.ensembl.org/id/ENSBTAG00000018534" } ] } } ], "crossref": [ { "id": "F6PX95", "url": "https://alphafold.ebi.ac.uk/entry/F6PX95", "database": "AlphaFoldDB", "categories": [] }, { "id": "IPR019148", "url": "https://www.ebi.ac.uk/interpro/entry/IPR019148", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "PTHR12940", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR12940", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR12940:SF0", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR12940:SF0", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF09751", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF09751", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "F6PX95", "url": "https://www.uniprot.org/uniprotkb/F6PX95", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "F6PX95-1", "url": 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"MSDIRHSLLRRDALSAAKEVLYHLDIYFSSQLQSAPLPIVDKGPVELLEEFVFQVPKERGAQPKEQTKDSVRQIIFSSLFSPQGNKADDSRMSLLGKLVSMAVAVCRIPVLECAASWLQRTPVAYCVRLARALVDDYCCLVPGSVQTLRQILSASPRFCCQFITSVTALYDLSSDDLIPPLDLLEMIVNWILEDPSVLQVLLMLQAHLTEKNLYGRLGLVLFDHMVPLVEEVNRLADELNPLNASQEIELALDRLAQALQVAMASGALLCTRDDLRTLCSRLPHNNLLQLVISGPVQQSPHTALPPGFYPHIHTPPLGYGAVPAHPAAHPALPTHPGHTFISGMTFPFRPIH", "length": 352, "header": "tr|F6Q4N6-1|F6Q4N6_BOVIN Isoform 1 of Integrator complex subunit 15 OS=Bos taurus OX=9913 GN=INTS15 PE=4 SV=1 CANONICAL=F6Q4N6-1" }, "isoforms": [ { "isoform_ac": "F6Q4N6-1", "url": "https://www.uniprot.org/uniprotkb/F6Q4N6/entry", "sequence": { "sequence": "MSDIRHSLLRRDALSAAKEVLYHLDIYFSSQLQSAPLPIVDKGPVELLEEFVFQVPKERGAQPKEQTKDSVRQIIFSSLFSPQGNKADDSRMSLLGKLVSMAVAVCRIPVLECAASWLQRTPVAYCVRLARALVDDYCCLVPGSVQTLRQILSASPRFCCQFITSVTALYDLSSDDLIPPLDLLEMIVNWILEDPSVLQVLLMLQAHLTEKNLYGRLGLVLFDHMVPLVEEVNRLADELNPLNASQEIELALDRLAQALQVAMASGALLCTRDDLRTLCSRLPHNNLLQLVISGPVQQSPHTALPPGFYPHIHTPPLGYGAVPAHPAAHPALPTHPGHTFISGMTFPFRPIH", "length": 352, "header": "tr|F6Q4N6-1|F6Q4N6_BOVIN Isoform 1 of Integrator complex subunit 15 OS=Bos taurus OX=9913 GN=INTS15 PE=4 SV=1 CANONICAL=F6Q4N6-1" }, "locus": { "chromosome": "25", "start_pos": 38429815, "end_pos": 38419250, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000028313.6", "url": "https://www.ensembl.org/id/ENSBTAT00000028313.6" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000028313.4", "url": "https://www.ensembl.org/id/ENSBTAP00000028313.4" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [], "orthologs": [], "go_annotation": { "categories": [ { "name": "Biological Process", "total": 2, "go_terms": [ { "name": "regulation of transcription elongation by RNA polymerase II", "id": "GO:0034243", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0034243", "evidence": [ { "database": "UniProtKB", "id": "F6Q4N6", "url": "https://www.uniprot.org/uniprotkb/F6Q4N6" } ], "pmid": "" }, { "name": "RNA polymerase II transcription initiation surveillance", "id": "GO:0160240", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0160240", "evidence": [ { "database": "UniProtKB", "id": "F6Q4N6", "url": "https://www.uniprot.org/uniprotkb/F6Q4N6" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 3, "go_terms": [ { "name": "chromosome", "id": "GO:0005694", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005694", "evidence": [ { "database": "UniProtKB", "id": "F6Q4N6", "url": "https://www.uniprot.org/uniprotkb/F6Q4N6" } ], "pmid": "" }, { "name": "integrator complex", "id": "GO:0032039", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0032039", "evidence": [ { "database": "UniProtKB", "id": "F6Q4N6", "url": "https://www.uniprot.org/uniprotkb/F6Q4N6" } ], "pmid": "" }, { "name": "INTAC complex", "id": "GO:0160232", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0160232", "evidence": [ { "database": "UniProtKB", "id": "F6Q4N6", "url": "https://www.uniprot.org/uniprotkb/F6Q4N6" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 243, "end_pos": 245, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 243, "end_pos": 245 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": 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"n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": 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"url": "https://www.uniprot.org/uniprotkb/A0AAA9TXT2#function" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Bos taurus", "taxid": 9913, "evidence": [ { "database": "UniProtKB", "id": "F6Q565", "url": "https://www.uniprot.org/uniprotkb/F6Q565" } ], "common_name": "Bovine", "glygen_name": "Bovine", "reference_species": "Bos taurus [9913]" } ], "gene": [ { "name": "DCAF4", "url": "https://www.uniprot.org/uniprotkb/F6Q565", "locus": {} } ], "crossref": [ { "id": "F6Q565", "url": "https://alphafold.ebi.ac.uk/entry/F6Q565", "database": "AlphaFoldDB", "categories": [] }, { "id": "IPR001680", "url": "https://www.ebi.ac.uk/interpro/entry/IPR001680", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR015943", "url": "https://www.ebi.ac.uk/interpro/entry/IPR015943", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR036322", "url": "https://www.ebi.ac.uk/interpro/entry/IPR036322", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR052254", "url": "https://www.ebi.ac.uk/interpro/entry/IPR052254", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "PTHR44472", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR44472", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR44472:SF1", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR44472:SF1", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF23761", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF23761", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "A0AAA9TXT2", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TXT2", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0AAA9TXT2-1", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TXT2-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0ABI0NXV9", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NXV9", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0ABI0NXV9-1", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NXV9-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "F6Q565", "url": "https://www.uniprot.org/uniprotkb/F6Q565", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "F6Q565-1", "url": "https://www.uniprot.org/uniprotkb/F6Q565-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MHQSSWKSRRHRRRGHRHNAWFRPHGSNERQDAGVQQSPQGSSDGHGEAPSTSSTAGSSSVPDLPGYYFDPEKKRYFRLLPGHNNCNPLTKESIRQKEMERKRLRLLEEEEQQGKKIARLGFNASSLLQKSKLGFLNATSYCRLAQELRVSCMQRKKVQIQSSDPSALASDQFNLIMADTNSDRLFTVNDVKVGGSKYGIISLHGLKTPTFRVHMHENLYFTNRKVNAMCWASLNHLDSHVLLCLMGIAETPGCATLLPTSLFVSNHAAGDRPGMLCSFRIPGAWSCAWSLNIQANNCFSTGLSRRVLVTSVVTGHRQSFGTSSDVLTQQFAVTAPLLFNGCRSGEIFAIDLRCQNQGKGWKATCLFHDSAVTSVQILQEEQCLMASDMAGTIKLWDLRTTKCIRQYEGHVNEYAHLPLHVHEEEGIMVAVGQDCYTRIWSLHDGQLLRTIPSPYPTSKADIPSVAFSSRLGGARGAPGLLMAVRQDLYCFSYS", "length": 494, "header": "tr|F6Q565-1|F6Q565_BOVIN Isoform 1 of DDB1- and CUL4-associated factor 4 OS=Bos taurus OX=9913 GN=DCAF4 PE=4 SV=1 CANONICAL=F6Q565-1" }, "isoforms": [ { "isoform_ac": "A0AAA9TXT2-1", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TXT2/entry", "sequence": { "sequence": "YLDSAWQSRVETRRTAILCTPHGKKGRADAGVQQSPQGSSDGHGEAPSTSSTAGSSSVPDLPGYYFDPEKKRYFRLLPGHNNCNPLTKESIRQKEMERKRLRLLEEEEQQGKKIARLGFNASSLLQKSKLGFLNATSYCRLAQELRVSCMQRKKVQIQSSDPSALASDQFNLIMADTNSDRLFTVNDVKVGGSKYGIISLHGLKTPTFRVHMHENLYFTNRKVNAMCWASLNHLDSHVLLCLMGIAETPGCATLLPTSLFVSNHAAGDRPGMLCSFRIPGAWSCAWSLNIQANNCFSTGLSRRVLVTSVVTGHRQSFGTSSDVLTQQFAVTAPLLFNGCRSGEIFAIDLRCQNQGKGWKATCLFHDSAVTSVQILQEEQCLMASDMAGTIKLWDLRTTKCIRQYEGHVNEYAHLPLHVHEEEGIMVAVGQDCYTRIWSLHDGQLLRTIPSPYPTSKADIPSVAFSSRLGGARGAPGLLMAVRQDLYCFSYS", "length": 491, "header": "tr|A0AAA9TXT2-1|A0AAA9TXT2_BOVIN Computationally mapped isoform of DDB1- and CUL4-associated factor 4 OS=Bos taurus OX=9913 GN=DCAF4 PE=4 SV=2 CANONICAL=F6Q565-1" }, "locus": { "chromosome": "10", "start_pos": 84480243, "end_pos": 84465359, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000109475.2", "url": "https://www.ensembl.org/id/ENSBTAT00000109475.2" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000102012.2", "url": "https://www.ensembl.org/id/ENSBTAP00000102012.2" } ] } }, { "isoform_ac": "A0ABI0NXV9-1", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NXV9/entry", "sequence": { "sequence": "MHQSSWKSRRHRRRGHRHNAWFRPHGSNERQDAGVQQSPQGSSDGHGEAPSTSSTAGSSSVPDLPGYYFDPEKKRYFRLLPGHNNCNPLTKESIRQKEMERKRLRLLEEEEQQGKKIARLGFNASSLLQKSKLGFLNATSYCRLAQELRVSCMQRKKVQIQSSDPSALASDQFNLIMVNAMCWASLNHLDSHVLLCLMGIAETPGCATLLPTSLFVSNHAAGDRPGMLCSFRIPGAWSCAWSLNIQANNCFSTGLSRRVLVTSVVTGHRQSFGTSSDVLTQQFAVTAPLLFNGCRSGEIFAIDLRCQNQGKGWKATCLFHDSAVTSVQILQEEQCLMASDMAGTIKLWDLRTTKCIRQYEGHVNEYAHLPLHVHEEEGIMVAVGQDCYTRIWSLHDGQLLRTIPSPYPTSKADIPSVAFSSRLGGARGAPGLLMAVRQDLYCFSYS", "length": 446, "header": "tr|A0ABI0NXV9-1|A0ABI0NXV9_BOVIN Computationally mapped isoform of DDB1 and CUL4 associated factor 4 OS=Bos taurus OX=9913 GN=DCAF4 PE=4 SV=1 CANONICAL=F6Q565-1" }, "locus": { "chromosome": "10", "start_pos": 84480243, "end_pos": 84464044, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000144750.1", "url": "https://www.ensembl.org/id/ENSBTAT00000144750.1" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000106170.1", "url": "https://www.ensembl.org/id/ENSBTAP00000106170.1" } ] } }, { "isoform_ac": "F6Q565-1", "url": "https://www.uniprot.org/uniprotkb/F6Q565/entry", "sequence": { "sequence": "MHQSSWKSRRHRRRGHRHNAWFRPHGSNERQDAGVQQSPQGSSDGHGEAPSTSSTAGSSSVPDLPGYYFDPEKKRYFRLLPGHNNCNPLTKESIRQKEMERKRLRLLEEEEQQGKKIARLGFNASSLLQKSKLGFLNATSYCRLAQELRVSCMQRKKVQIQSSDPSALASDQFNLIMADTNSDRLFTVNDVKVGGSKYGIISLHGLKTPTFRVHMHENLYFTNRKVNAMCWASLNHLDSHVLLCLMGIAETPGCATLLPTSLFVSNHAAGDRPGMLCSFRIPGAWSCAWSLNIQANNCFSTGLSRRVLVTSVVTGHRQSFGTSSDVLTQQFAVTAPLLFNGCRSGEIFAIDLRCQNQGKGWKATCLFHDSAVTSVQILQEEQCLMASDMAGTIKLWDLRTTKCIRQYEGHVNEYAHLPLHVHEEEGIMVAVGQDCYTRIWSLHDGQLLRTIPSPYPTSKADIPSVAFSSRLGGARGAPGLLMAVRQDLYCFSYS", "length": 494, "header": "tr|F6Q565-1|F6Q565_BOVIN Isoform 1 of DDB1- and CUL4-associated factor 4 OS=Bos taurus OX=9913 GN=DCAF4 PE=4 SV=1 CANONICAL=F6Q565-1" }, "locus": { "chromosome": "10", "start_pos": 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"database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF13855", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF13855", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "R-BTA-193634", "url": "https://www.reactome.org/PathwayBrowser/#R-BTA-193634", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "NP_001070992", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001070992", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "F6Q889", "url": "https://www.uniprot.org/uniprotkb/F6Q889", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "F6Q889-1", "url": "https://www.uniprot.org/uniprotkb/F6Q889-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MALMEYQILKMSPSLFILLFLTPGILCICPLQCICTERHRHVDCSGRNLTTLPSGLQENIIHLNLSYNHFTDLHNQLTQYTNLRTLDISNNRLESLPAQLPRSLWNMSAANNNIKLLEKSDTAYQWNLKYLDVSKNMLEKVVLIKNTLRSLEVLNLSSNKLWTVPTNMPSKLHTVDLSNNSLTQILPGTLINLTNLTHLYLHNNKFTFIPDQAFDQLFQLQEITLYNNRWSCDHHQNITYLLKWMMETKAHVIGTPCSSQISSLKEHSIYPTPSGFTSSLFTVSGMQTVDTINSLSTVTQSKVTKIPKQYRTKETTFGATLSKDTTLTSTDKAFVPYPEDTSTETINSREAAAATLTIHLQDGMVTNTSLTSSTKSSPTPMTLSITSGMPNDFSEMPQQSTTLNLRREETTTDGKTRLPSVASAWKVNASFLLMLNAVVMLAV", "length": 443, "header": "tr|F6Q889-1|F6Q889_BOVIN Isoform 1 of Oligodendrocyte-myelin glycoprotein OS=Bos taurus OX=9913 GN=OMG PE=4 SV=1 CANONICAL=F6Q889-1" }, "isoforms": [ { "isoform_ac": "F6Q889-1", "url": "https://www.uniprot.org/uniprotkb/F6Q889/entry", "sequence": { "sequence": "MALMEYQILKMSPSLFILLFLTPGILCICPLQCICTERHRHVDCSGRNLTTLPSGLQENIIHLNLSYNHFTDLHNQLTQYTNLRTLDISNNRLESLPAQLPRSLWNMSAANNNIKLLEKSDTAYQWNLKYLDVSKNMLEKVVLIKNTLRSLEVLNLSSNKLWTVPTNMPSKLHTVDLSNNSLTQILPGTLINLTNLTHLYLHNNKFTFIPDQAFDQLFQLQEITLYNNRWSCDHHQNITYLLKWMMETKAHVIGTPCSSQISSLKEHSIYPTPSGFTSSLFTVSGMQTVDTINSLSTVTQSKVTKIPKQYRTKETTFGATLSKDTTLTSTDKAFVPYPEDTSTETINSREAAAATLTIHLQDGMVTNTSLTSSTKSSPTPMTLSITSGMPNDFSEMPQQSTTLNLRREETTTDGKTRLPSVASAWKVNASFLLMLNAVVMLAV", "length": 443, "header": "tr|F6Q889-1|F6Q889_BOVIN Isoform 1 of Oligodendrocyte-myelin glycoprotein OS=Bos taurus OX=9913 GN=OMG PE=4 SV=1 CANONICAL=F6Q889-1" }, "locus": { "chromosome": "19", "start_pos": 18693105, "end_pos": 18690952, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000035344.3", "url": "https://www.ensembl.org/id/ENSBTAT00000035344.3" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000035220.3", "url": "https://www.ensembl.org/id/ENSBTAP00000035220.3" } ] } } ], "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "other", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 272, "start_aa": "Thr", "end_pos": 272, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr272", "evidence": [ { "id": "", "database": "GlyGen", "url": "https://data.glygen.org/" } ], "filter_code": "000000000000000010000.00000000001000.0.01000" } ], "phosphorylation": [], "glycation": [], "keywords": [ "glycoprotein", "glycoprotein_predicted" ], "publication": [], "pathway": [ { "id": "bta:407186", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?bta:407186", "resource": "KEGG Pathway" }, { "id": "R-BTA-193634", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-BTA-193634", "resource": "Reactome", "description": "Axonal growth inhibition (RHOA activation)" } ], "orthologs": [ { "uniprot_canonical_ac": "E1C1K8-1", "protein_name": "Oligodendrocyte-myelin glycoprotein", "gene_name": "OMG", "tax_id": 9031, "organism": "Gallus gallus", "sequence": { "sequence": "MEHQILKTSTCLLVLLFFIPTVLGICPSNCTCSGNNRNVDCSGRNLTVLPHGLQDNITYLNLSFNQFVDLDHQLTRFSNLRTLDISNNWLKNVPAHLPKSLWELYAINNNIKVLQKLDTAYQWNLKVLDVSRNMVERAVLINNTLSSLKFLNLSSNKLWTVPTNMPYNIETVDLSNNFLSQILPGTLVRLQHLTSLYLHNNKFTYIPDKAFDQLFQLQVVTLYNNPWSCSNEQNISYLLKWVHSTTARVRGAPCADQSMLWANVTPTSATAPDASFMIKGMKAADTPAAAEPTQMTKMHKQFKAKEITTLASLSQTVLFTSTDRPLLLYPEELTTRKVSAYEAAATHTIYIKDTTEVNSSLTHSTGSSTTPMTLSITSGMPTNYSRMPQSTTATLRREEATTSVLNTDVPSKASICAICLFYAVMLNAVAAFIG", "length": 434 }, "evidence": [ { "id": "F6Q889", "url": "https://omabrowser.org/oma/group/F6Q889/", "database": "OMA" } ], "glygen_name": "Chicken", "common_name": "Chicken" }, { "uniprot_canonical_ac": "F1RJ55-1", "protein_name": "Oligodendrocyte-myelin glycoprotein", "gene_name": "OMG", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MALMEYQILKMSPSLFILLLLTPGILCICPLQCICTERHRHVDCSGRNLTTLPSGLQENIIHLNLSYNHFTDLHNQLTQYTNLRTLDISNNRLESLPAQLPRSLWNMSAANNNIKLLEKSDTAYQWNLKYLDVSKNMLEKVVLIKNTLRSLEVLNLSSNKLWTVPTNMPSKLHIVDLSHNSLTQILPGTLINLTNLTHLYLHNNKFTFIPDQAFDQLLQLQEITLYNNRWSCDHQQNITYLLKWMMETKAHVIGTPCSSQISSLKEHSIYPTPPGFTSSLFTLSGIQTVDTINSLSMVTQSKVTKIPKQYRTKETFGATLSKDTTFTSTDKAFVPYPEDTSTEMINSHEAAAATLTIHLQDGMVTNTSLTSSTKSSPTPMTLSITSGMPNNFSEMPQQSTTLNLRREETTTNVKTRSPSSVANAWKVNALFLLMLNAVVMLAV", "length": 443 }, "evidence": [ { "id": "F6Q889", "url": "https://omabrowser.org/oma/group/F6Q889/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "F7EYB9-1", "protein_name": "Oligodendrocyte-myelin glycoprotein", "gene_name": "Omg", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MALMEYQILKMSSCLFILLFLTPGILCICPLQCICTERHRHVDCSGRNLTTLPPGLQENIIHLNLSYNHFTDLHNQLTPYTNLRTLDISNNRLESLPAQLPRSLWNMSAANNNIKLLDKSDTAYQWNLKYLDVSKNMLEKVVLIKNTLRSLEVLNLSSNKLWTVPTNMPSKLHIVDLSNNSLTQILPGTLINLTNLTHLYLHNNKFTFIPDQSFDQLLQLQEITLHNNRWSCDHTQNITYLLKWMMETKAHVIGIPCSKQVSSLKEQSMYPTPPGFTSSLFTMSEMQTVDTINSLSMVTQPKVTNIPKQYRGKDTTFGVTLSKDTTFSSTDRALEPYPEDTPTEMTSSREAAAATLTIHLQDGMSSNASLTSAAKSSPAPVTLSITSGMPNNFSEMPQQSTTLNLRREETTANVKTQPPSSASAWKVNASLLLMLNAVVMLAG", "length": 443 }, "evidence": [ { "id": "F6Q889", "url": "https://omabrowser.org/oma/group/F6Q889/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "P23515-1", "protein_name": "Oligodendrocyte-myelin glycoprotein", "gene_name": "OMG", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MEYQILKMSLCLFILLFLTPGILCICPLQCICTERHRHVDCSGRNLSTLPSGLQENIIHLNLSYNHFTDLHNQLTQYTNLRTLDISNNRLESLPAHLPRSLWNMSAANNNIKLLDKSDTAYQWNLKYLDVSKNMLEKVVLIKNTLRSLEVLNLSSNKLWTVPTNMPSKLHIVDLSNNSLTQILPGTLINLTNLTHLYLHNNKFTFIPDQSFDQLFQLQEITLYNNRWSCDHKQNITYLLKWMMETKAHVIGTPCSTQISSLKEHNMYPTPSGFTSSLFTVSGMQTVDTINSLSVVTQPKVTKIPKQYRTKETTFGATLSKDTTFTSTDKAFVPYPEDTSTETINSHEAAAATLTIHLQDGMVTNTSLTSSTKSSPTPMTLSITSGMPNNFSEMPQQSTTLNLWREETTTNVKTPLPSVANAWKVNASFLLLLNVVVMLAV", "length": 440 }, "evidence": [ { "id": "F6Q889", "url": "https://omabrowser.org/oma/group/F6Q889/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "Q63912-1", "protein_name": "Oligodendrocyte-myelin glycoprotein", "gene_name": "Omg", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MEYQILKMSSCLFILLFLTPGILCICPLQCTCTERHRHVDCSGRNLTTLPPGLQENIIHLNLSYNHFTDLHNQLTPYTNLRTLDISNNRLESLPAQLPRSLWNMSAANNNIKLLDKSDTAYQWNLKYLDVSKNMLEKVVLIKNTLRSLEVLNLSSNKLWTVPTNMPSKLHIVDLSNNSLTQILPGTLINLTNLTHLYLHNNKFTFIPEQSFDQLLQLQEITLHNNRWSCDHKQNITYLLKWVMETKAHVIGTPCSKQVSSLKEQSMYPTPPGFTSSLFTMSEMQTVDTINSLSMVTQPKVTKTPKQYRGKETTFGVTLSKDTTFSSTDRAVVAYPEDTPTEMTNSHEAAAATLTIHLQDGMSSNASLTSATKSPPSPVTLSIARGMPNNFSEMPRQSTTLNLRREETTANGNTRPPSAASAWKVNASLLLMLNAVVMLAG", "length": 440 }, "evidence": [ { "id": "F6Q889", "url": "https://omabrowser.org/oma/group/F6Q889/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" } ], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 2, "go_terms": [ { "name": "plasma membrane", "id": "GO:0005886", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005886", "evidence": [ { "database": "UniProtKB", "id": "F6Q889", "url": "https://www.uniprot.org/uniprotkb/F6Q889" } ], "pmid": "" }, { "name": "side of membrane", "id": "GO:0098552", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0098552", "evidence": [ { "database": "UniProtKB", "id": "F6Q889", "url": "https://www.uniprot.org/uniprotkb/F6Q889" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 2, "go_terms": [ { "name": "cell adhesion", "id": "GO:0007155", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007155", "evidence": [ { "database": "UniProtKB", "id": "F6Q889", "url": "https://www.uniprot.org/uniprotkb/F6Q889" } ], "pmid": "" }, { "name": "neuron projection regeneration", "id": "GO:0031102", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0031102", "evidence": [ { "database": "UniProtKB", "id": "F6Q889", "url": "https://www.uniprot.org/uniprotkb/F6Q889" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 106, "end_pos": 108, "annotation": "n_glycosylation_sequon" }, { "start_pos": 155, "end_pos": 157, "annotation": "n_glycosylation_sequon" }, { "start_pos": 179, "end_pos": 181, "annotation": "n_glycosylation_sequon" }, { "start_pos": 192, "end_pos": 194, "annotation": "n_glycosylation_sequon" }, { "start_pos": 195, "end_pos": 197, "annotation": "n_glycosylation_sequon" }, { "start_pos": 237, "end_pos": 239, "annotation": "n_glycosylation_sequon" }, { "start_pos": 367, "end_pos": 369, "annotation": "n_glycosylation_sequon" }, { "start_pos": 428, "end_pos": 430, "annotation": "n_glycosylation_sequon" }, { "start_pos": 48, "end_pos": 50, "annotation": "n_glycosylation_sequon" }, { "start_pos": 64, "end_pos": 66, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [ { "pdb_id": "AF-F6Q889-F1", "pdb_chain": "global", "start_pos": 1, "end_pos": 443, "overlap": "1.0", "method": "AlphaFold", "type": "alphafold", "resolution": -1.0, "url": "https://data.glygen.org/ln2downloads/pdb/current/AF-F6Q889-F1.pdb", "url_external": "https://alphafold.ebi.ac.uk/entry/F6Q889" } ], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "F6Q889", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F6Q889" }, { "id": "SM00013", "database": "SMART", "url": "http://smart.embl.de/smart/do_annotation.pl?DOMAIN=SM00013" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "LRRNT", "eco_id": "ECO_0000259", "start_pos": 28, "end_pos": 62, "start_aa": "Ile", "end_aa": "His", "glycosite_overlap": [] } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "homologset.oma", "label": "OMA Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [ 272 ], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 106, "end_pos": 108 }, { "start_pos": 155, "end_pos": 157 }, { "start_pos": 179, "end_pos": 181 }, { "start_pos": 192, "end_pos": 194 }, { "start_pos": 195, "end_pos": 197 }, { "start_pos": 237, "end_pos": 239 }, { "start_pos": 367, "end_pos": 369 }, { "start_pos": 428, "end_pos": 430 }, { "start_pos": 48, "end_pos": 50 }, { "start_pos": 64, "end_pos": 66 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 1 }, { "field": "total_sites", "count": 1 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 1 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "exact_sites", "count": 1 }, { "field": "exact_o_linked_sites", "count": 1 }, { "field": "fuzzy_sites", "count": 0 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_pos", "start_aa", "end_pos", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": 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"count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ], "tool_support": { "graph_view": "yes" } }, { "uniprot_canonical_ac": "F6Q8D9-1", "uniprot_ac": "F6Q8D9", "uniprot_id": "F6Q8D9_BOVIN", "mass": { "chemical_mass": 82205.0, "monoisotopic_mass": 82205.0 }, "refseq": {}, "gene_names": [ { "name": "TROAP", "type": "recommended", "evidence": [ { "id": "F6Q8D9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F6Q8D9" } ] } ], "protein_names": [ { "name": "Trophinin associated protein", "type": "synonym", "evidence": [ { "id": "F6Q8D9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F6Q8D9/entry#names_and_taxonomy" } ] } ], "function": [], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Bos taurus", "taxid": 9913, "evidence": [ { "database": "UniProtKB", "id": "F6Q8D9", "url": "https://www.uniprot.org/uniprotkb/F6Q8D9" } ], "common_name": "Bovine", "glygen_name": "Bovine", "reference_species": "Bos taurus [9913]" } ], "gene": [ { "name": "TROAP", "url": "https://www.uniprot.org/uniprotkb/F6Q8D9", "locus": { "chromosome": "5", "start_pos": 30488677, "end_pos": 30495848, "strand": "+", "evidence": [ { "database": "Ensembl Gene", "id": "ENSBTAG00000008499", "url": "https://www.ensembl.org/id/ENSBTAG00000008499" } ] } } ], "crossref": [ { "id": "F6Q8D9", "url": "https://alphafold.ebi.ac.uk/entry/F6Q8D9", "database": "AlphaFoldDB", "categories": [] }, { "id": "IPR026133", "url": "https://www.ebi.ac.uk/interpro/entry/IPR026133", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "PTHR15289", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR15289", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR15289:SF3", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR15289:SF3", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "F6Q8D9", "url": "https://www.uniprot.org/uniprotkb/F6Q8D9", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "F6Q8D9-1", "url": "https://www.uniprot.org/uniprotkb/F6Q8D9-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MTTLQAPKDPLLRGVSPTPSKIPVRSQRRPPLPTVKPSALDQENQDPKRLGQKLSIQRPLADSAGPRLKATRQTEQSEKLVGSTQLRNPLEELRPSHGGQNVGPRPPPQTEAPGTIEFVADPAALATILSGEGVKSCRLGRQPSLAQRVLVRGTQGGTIRKGQDARASAYLAPRTPTHRLDPVRASCFSRLEGPGPRGRTLCPQRLEALIPPSGSSSHPSALPCFQELRRETSGSSKTSVSQASGSLPETSVQPGECVWPWGENVSWEPACREQTERKLRRAVAGRPDQEETERKRSSSQATASSLPEGEHEVVTQSDEGGGGPLGLAQRIPLKETRDKTHTRDGCDSCLMPSPGQAVPPAITRPSPFGRAQRVPSPGPSAPISYSVLRRLATRPRTQFTPLPSASRVQQARGLSGLSPQPCPEEPALPWEQIAVRLFDQESGIRLQEGPGKPPVSTSYGPHPSRTPNLQELKMQRISILQQLLRQEVEGLAEGKCAPLNESSSLDMVELQPLLAEISRTLNAPEKIPGAFHLSGLLQHPELPKPYFPEECGKPDPCPRAEPEIAPPCPPAEQGPPESCHGRGPEKPELSTQEQPEASGPSPPAEPGPLQACPQGQIGLPEPSTRVDPGVSEACSLELRNPESSPRPRTSQWAPATTSLTFSSQRPLCASPPIRSLQSLKPSPGPAGASHPAPRTMALRQRLKACLTAIHGFHEACLDDECAFYTSRAPPSGLTRVCTNPVAMLLEWQDALCFIPVGDAAPQDSPS", "length": 766, "header": "tr|F6Q8D9-1|F6Q8D9_BOVIN Isoform 1 of Trophinin associated protein OS=Bos taurus OX=9913 GN=TROAP PE=4 SV=1 CANONICAL=F6Q8D9-1" }, "isoforms": [ { "isoform_ac": "F6Q8D9-1", "url": "https://www.uniprot.org/uniprotkb/F6Q8D9/entry", "sequence": { "sequence": "MTTLQAPKDPLLRGVSPTPSKIPVRSQRRPPLPTVKPSALDQENQDPKRLGQKLSIQRPLADSAGPRLKATRQTEQSEKLVGSTQLRNPLEELRPSHGGQNVGPRPPPQTEAPGTIEFVADPAALATILSGEGVKSCRLGRQPSLAQRVLVRGTQGGTIRKGQDARASAYLAPRTPTHRLDPVRASCFSRLEGPGPRGRTLCPQRLEALIPPSGSSSHPSALPCFQELRRETSGSSKTSVSQASGSLPETSVQPGECVWPWGENVSWEPACREQTERKLRRAVAGRPDQEETERKRSSSQATASSLPEGEHEVVTQSDEGGGGPLGLAQRIPLKETRDKTHTRDGCDSCLMPSPGQAVPPAITRPSPFGRAQRVPSPGPSAPISYSVLRRLATRPRTQFTPLPSASRVQQARGLSGLSPQPCPEEPALPWEQIAVRLFDQESGIRLQEGPGKPPVSTSYGPHPSRTPNLQELKMQRISILQQLLRQEVEGLAEGKCAPLNESSSLDMVELQPLLAEISRTLNAPEKIPGAFHLSGLLQHPELPKPYFPEECGKPDPCPRAEPEIAPPCPPAEQGPPESCHGRGPEKPELSTQEQPEASGPSPPAEPGPLQACPQGQIGLPEPSTRVDPGVSEACSLELRNPESSPRPRTSQWAPATTSLTFSSQRPLCASPPIRSLQSLKPSPGPAGASHPAPRTMALRQRLKACLTAIHGFHEACLDDECAFYTSRAPPSGLTRVCTNPVAMLLEWQDALCFIPVGDAAPQDSPS", "length": 766, "header": "tr|F6Q8D9-1|F6Q8D9_BOVIN Isoform 1 of Trophinin associated protein OS=Bos taurus OX=9913 GN=TROAP PE=4 SV=1 CANONICAL=F6Q8D9-1" }, "locus": { "chromosome": "5", "start_pos": 30495555, "end_pos": 30489259, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000011203.6", "url": "https://www.ensembl.org/id/ENSBTAT00000011203.6" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000011203.5", "url": "https://www.ensembl.org/id/ENSBTAP00000011203.5" } ] } } ], "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "other", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 18, "start_aa": "Thr", "end_pos": 18, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr18", "evidence": [ { "id": "", "database": "GlyGen", "url": "https://data.glygen.org/" } ], "filter_code": "000000000000000010000.00000000001000.0.01000" } ], "phosphorylation": [], "glycation": [], "keywords": [ "glycoprotein", "glycoprotein_predicted" ], "publication": [], "pathway": [], "orthologs": [], "go_annotation": {}, "pro_annotation": [], "site_annotation": [ { "start_pos": 264, "end_pos": 266, "annotation": "n_glycosylation_sequon" }, { "start_pos": 500, "end_pos": 502, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [ 18 ], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 264, "end_pos": 266 }, { "start_pos": 500, "end_pos": 502 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 1 }, { "field": "total_sites", "count": 1 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 1 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "exact_sites", "count": 1 }, { "field": "exact_o_linked_sites", "count": 1 }, { "field": "fuzzy_sites", "count": 0 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_pos", "start_aa", "end_pos", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 1 }, { "field": "total_sites", "count": 1 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 1 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "exact_sites", "count": 1 }, { "field": "exact_o_linked_sites", "count": 1 }, { "field": "fuzzy_sites", "count": 0 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_pos", "start_aa", "end_pos", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ], "tool_support": { "graph_view": "yes" } }, { "uniprot_canonical_ac": "F6Q9U9-1", "uniprot_ac": "F6Q9U9", "uniprot_id": "F6Q9U9_BOVIN", "mass": { "chemical_mass": 37141.0, "monoisotopic_mass": 37141.0 }, "refseq": { "ac": "XP_010819873", "name": "calcium/calmodulin-dependent protein kinase type 1B isoform X3", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_010819873" }, "gene_names": [ { "name": "PNCK", "type": "recommended", "evidence": [ { "id": "F6Q9U9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F6Q9U9" } ] }, { "name": "PNCK", "type": "synonym", "evidence": [ { "id": "XP_010819873", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_010819873" } ] } ], "protein_names": [ { "name": "calcium/calmodulin-dependent protein kinase", "type": "recommended", "evidence": [ { "id": "F6Q9U9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F6Q9U9/entry#names_and_taxonomy" } ] }, { "name": "2.7.11.17", "type": "synonym", "evidence": [ { "id": "F6Q9U9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F6Q9U9/entry#names_and_taxonomy" } ] }, { "name": "calcium/calmodulin-dependent protein kinase type 1B isoform X3", "type": "synonym", "evidence": [ { "id": "XP_010819873", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_010819873" } ] } ], "function": [], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Bos taurus", "taxid": 9913, "evidence": [ { "database": "UniProtKB", "id": "F6Q9U9", "url": "https://www.uniprot.org/uniprotkb/F6Q9U9" } ], "common_name": "Bovine", "glygen_name": "Bovine", "reference_species": "Bos taurus [9913]" } ], "gene": [ { "name": "PNCK", "url": "https://www.uniprot.org/uniprotkb/F6Q9U9", "locus": { "chromosome": "X", "start_pos": 36891606, "end_pos": 36895157, "strand": "+", "evidence": [ { "database": "Ensembl Gene", "id": "ENSBTAG00000017430", "url": "https://www.ensembl.org/id/ENSBTAG00000017430" } ] } } ], "crossref": [ { "id": "F6Q9U9", "url": "https://alphafold.ebi.ac.uk/entry/F6Q9U9", "database": "AlphaFoldDB", "categories": [] }, { "id": "614251", "url": "https://www.ncbi.nlm.nih.gov/gene/614251", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR000719", "url": "https://www.ebi.ac.uk/interpro/entry/IPR000719", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR008271", "url": "https://www.ebi.ac.uk/interpro/entry/IPR008271", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR011009", "url": "https://www.ebi.ac.uk/interpro/entry/IPR011009", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "PTHR24347", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR24347", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00069", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00069", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "XP_010819873", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_010819873", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "17989", "url": "https://www.rhea-db.org/rhea/17989", "database": "Rhea", "categories": [ "Enzyme and Pathway" ] }, { "id": "46608", "url": "https://www.rhea-db.org/rhea/46608", "database": "Rhea", "categories": [ "Enzyme and Pathway" ] }, { "id": "F6Q9U9", "url": "https://www.uniprot.org/uniprotkb/F6Q9U9", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "F6Q9U9-1", "url": "https://www.uniprot.org/uniprotkb/F6Q9U9-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MRSARSSARECVGAFSEVVLAQERGSSHLVALKCIPKKALRGKEALVENEIAVLRRVSHPNIVALEDVHESPSHLYLAMELVTGGELFDRIMERGSYTEKDASHLVAQVLGAVSYLHSLGIVHRDLKPENLLYATPFEDSKIMVSDFGLSKIQAGNMLGTACGTPGYVAPELLEQKPYGKAVDVWALGVISYILLCGYPPFYDESDPELFSQILRANYEFDSPFWDDISESAKDFIRHLLERDPQKRFTCQQALQHLWISGDTAFDKDILGSVSEQIQKNFARNHWKRAFNATSFLRHIRKLGQSLENEASGRRVMSRSHPGLPTSQPPEW", "length": 331, "header": "tr|F6Q9U9-1|F6Q9U9_BOVIN Isoform 1 of calcium/calmodulin-dependent protein kinase OS=Bos taurus OX=9913 GN=PNCK PE=3 SV=1 CANONICAL=F6Q9U9-1" }, "isoforms": [ { "isoform_ac": "F6Q9U9-1", "url": "https://www.uniprot.org/uniprotkb/F6Q9U9/entry", "sequence": { "sequence": "MRSARSSARECVGAFSEVVLAQERGSSHLVALKCIPKKALRGKEALVENEIAVLRRVSHPNIVALEDVHESPSHLYLAMELVTGGELFDRIMERGSYTEKDASHLVAQVLGAVSYLHSLGIVHRDLKPENLLYATPFEDSKIMVSDFGLSKIQAGNMLGTACGTPGYVAPELLEQKPYGKAVDVWALGVISYILLCGYPPFYDESDPELFSQILRANYEFDSPFWDDISESAKDFIRHLLERDPQKRFTCQQALQHLWISGDTAFDKDILGSVSEQIQKNFARNHWKRAFNATSFLRHIRKLGQSLENEASGRRVMSRSHPGLPTSQPPEW", "length": 331, "header": "tr|F6Q9U9-1|F6Q9U9_BOVIN Isoform 1 of calcium/calmodulin-dependent protein kinase OS=Bos taurus OX=9913 GN=PNCK PE=3 SV=1 CANONICAL=F6Q9U9-1" }, "locus": { "chromosome": "X", "start_pos": 36894399, "end_pos": 36892247, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000023169.6", "url": "https://www.ensembl.org/id/ENSBTAT00000023169.6" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000023169.5", "url": "https://www.ensembl.org/id/ENSBTAP00000023169.5" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [ "enzyme" ], "publication": [], "pathway": [], "orthologs": [], "go_annotation": { "categories": [ { "name": "Molecular Function", "total": 2, "go_terms": [ { "name": "ATP binding", "id": "GO:0005524", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005524", "evidence": [ { "database": "UniProtKB", "id": "F6Q9U9", "url": "https://www.uniprot.org/uniprotkb/F6Q9U9" } ], "pmid": "" }, { "name": "calcium/calmodulin-dependent protein kinase activity", "id": "GO:0004683", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0004683", "evidence": [ { "database": "UniProtKB", "id": "F6Q9U9", "url": "https://www.uniprot.org/uniprotkb/F6Q9U9" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 291, "end_pos": 293, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [ { "id": "17989", "name": "", "equation": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+)", "summary": "", "cellular_location": "", "input_participant_list": [], "output_participant_list": [], 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"A0AAF6YHL8-1", "Q08DZ2-1", "A0A3Q1LR28-1", "Q3MHJ9-1", "P00517-1", "Q3SYZ2-1", "A2VDU3-1", "Q3SWY6-1", "A0AAA9T5C9-1", "A7E3S4-1", "F1MI60-1", "E1BK52-1", "Q5E9X2-1", "Q17R13-1", "P68399-1", "F6Q6K1-1", "A0ABI0P0X3-1", "A0AAA9TNL3-1", "A0AAA9S4Z4-1", "E1B8P9-1", "Q2HJF7-1", "A0AAA9S9A9-1", "E1BG90-1", "F1MGX2-1", "A0A3Q1M4X3-1", "E1BN63-1", "A0A3Q1LNU2-1", "F1MKK7-1", "A0AAA9SMT9-1", "A0A3Q1MKC7-1", "A0A3Q1LTC6-1", "A0AAA9TD48-1", "A0A3Q1MEZ6-1", "E1BPU0-1", "A0A3Q1N707-1", "A0A3Q1LNA9-1", "F1MBN7-1", "E1BJM5-1", "F1MFK1-1", "A0A3Q1LKG0-1", "Q1RMT7-1", "G5E5D4-1", "F1MYV9-1", "A0AAA9T584-1", "A0AAA9SLY1-1", "Q2TA06-1", "Q5E9Y0-1", "A0AAA9RWB8-1", "A0AAA9SX77-1", "A0A3Q1MRR6-1", "A2VDV2-1", "A2VDZ4-1", "A5PKJ4-1", "E1BB50-1", "E1BB52-1", "F1MH24-1", "E1BCU9-1", "E1BFR5-1", "F1MDC9-1", "F1MNP4-1", "F1MQ96-1", "A0AAA9SU81-1", "P00516-1", "A0A3Q1LJU7-1", "A0A3Q1MS69-1", "A0A3Q1LU59-1", "A0A3Q1N4A7-1", "F1MY82-1", "F6RP02-1", "A7MBB4-1", "E1BMN8-1", "Q32KY4-1", "Q32PI1-1", "Q4TVR5-1", "Q5EAB2-1", "Q6TJY3-1", "E1B7H4-1", "E1BJ19-1", "E1BP01-1", "A0AAA9T940-1", "F1MC61-1", "E1BC64-1", "E1BNS8-1", "F1MPF0-1", "G5E518-1", "Q7YRC6-1", "Q95KV0-1", "Q9N0P9-1", "P20427-1", "P35507-1", "P35509-1", "P32871-1", "P35508-1", "P67827-1", "P04409-1", "P05126-1", "P05128-1", "P46196-1", "H2XJE9-1", "Q0VD22-1", "Q2KJG8-1", "Q2TBL8-1", "Q32L23-1", "Q3SX21-1", "Q3SZW1-1", "Q01314-1", "Q02399-1", "Q08E52-1", "Q0V7M1-1", "Q1RMT8-1", "Q2KIP2-1", "Q2LGB3-1", "Q2TA25-1", "Q3T0N5-1", "A0A3Q1LM61-1", "A0A3Q1LRM6-1", "E1BPB5-1", "A0A3Q1MHH5-1", "A0A3Q1M4N6-1", "G3MX00-1", "F1MH45-1", "A0A3Q1M334-1", "A0A3Q1M9L7-1", "A0A3Q1MA37-1", "A0A3Q1MHL3-1", "E1BP72-1", "A0AAA9T7Z7-1", "Q58D94-1", "F1MJ55-1", "Q17QV9-1", "F1N6C1-1", "G3N2F6-1", "A0AAA9T3K7-1", "F1MPI8-1", "F1MVV5-1", "F6RD87-1", "G3N2D2-1", "G5E577-1", "E1B887-1", "E1B902-1", "E1BAL6-1", "E1BH31-1", "E1BJH5-1", "E1BK33-1", "F1MG77-1", "F1MKW8-1", "A0AAA9SJQ0-1", "E1BL08-1", "E1B793-1", "E1B9B6-1", "E1BFV2-1", "A0AAA9T042-1", "A0AAA9TU12-1", "A0AAA9T593-1", "Q2YDN8-1", "A0AAA9SK35-1", "A0AAA9RSJ2-1", "A0AAA9T7I8-1", "Q3T0P6-1", "A0A3Q1LWT7-1", "A0AAA9S954-1", "E1B9F9-1", "A0AAA9RWC6-1", "F6RLA2-1", "E1BCH5-1", "H2XJE8-1", "A0A3Q1LL42-1", "A0AAA9SVM5-1", "F1MYG2-1", "A0A3Q1LLH8-1", "A0A3Q1LN49-1", "A0A3Q1M5T5-1", "A0A3Q1LW88-1", "A0ABI0P2C0-1", "A0AAA9SG01-1", "F6PN06-1", "E1BC36-1", "E1BB49-1", "E1BDG4-1", "E1BKX9-1", "E1BM19-1", "E1BQ34-1", "A0ABI0P443-1", "A0A3Q1LQP3-1", "A0A3Q1MNB4-1", "A0AAA9TWW0-1", "E1BGV8-1", "A0AAA9SIK7-1", "A0AAA9T8Z3-1", "F1N063-1", "A0A3Q1MD82-1", "F1N5K1-1", "E1BN72-1", "F1MLY7-1", "A0AAA9TVT5-1", "A0AAA9SKK8-1", "A0AAA9RTJ4-1", "A0AAA9TNE6-1", "F1MWP1-1", "G3N022-1", "A0AAA9TCI9-1", "A0AAA9TLV0-1", "E1B8J7-1", "F1MIB2-1", "E1B827-1", "E1BEI6-1", "A0A3Q1M1Z0-1", "F1MYM3-1", "G3N2J4-1", "F1MSV4-1", "E1B9Q2-1", "A0ABI0NJ75-1", "A0A3Q1M2U5-1", "A0A3Q1MI36-1", "A0A3Q1LLF0-1", "A0A3Q1M6N5-1", "A0A3Q1NFM1-1", "A0AAF6DLR2-1", "A0ABI0NV47-1", "E1BPP1-1", "E1BC69-1", "E1BCC3-1", "E1BEW4-1", "F1MF36-1", "A0AAA9SH90-1", "E1BLQ5-1", "F1MG35-1", "F1MSI1-1", "F1MSX4-1", "F1MVR0-1", "F1MY55-1", "G5E5A0-1", "F1MUU2-1", "F1MY86-1", "A0AAA9SJA3-1", "F6Q5Z6-1", "A0AAA9TP92-1", "A0AAA9S2N3-1", "A0A3Q1MHM3-1", "F6QY93-1", "F6Q5B6-1", "A0AAA9SYW5-1", "A0A3Q1LH95-1", "A0AAF6DMH7-1", "A0AAF6YMX3-1", "F6Q9U9-1", "A0A3Q1MW77-1", "F1MF50-1", "P52175-1", "Q8MIT6-1", "Q28021-1", "Q5E9Y9-1", "A0ABI0NMT8-1", "A0ABI0NRQ5-1", "F1MM88-1", "A0ABI0NM98-1", "A0ABI0NS30-1", "A0ABI0P3N8-1" ], "evidence": [ { "id": "17989", "database": "Rhea", "url": "https://www.rhea-db.org/rhea/17989" } ] }, { "id": "46608", "name": "", "equation": "L-threonyl-[protein] + ATP = O-phospho-L-threonyl-[protein] + ADP + H(+)", "summary": "", "cellular_location": "", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [ "G5E5K2-1", "V6F977-1", "A0A3Q1MRW3-1", "A0A3Q1N860-1", "E1BI01-1", "F6RG88-1", "A0AAA9T8T9-1", "A0AAA9U1R3-1", "A7E3X2-1", "A0AAA9U1M9-1", "E1B754-1", "A0AAA9T7L6-1", "A0A3Q1M9F0-1", "A0ABI0P3P6-1", "E1BNH0-1", "A0AAA9TMV7-1", "A0AAA9T2F0-1", "A0AAA9S663-1", "A0AAA9U1A4-1", "F1MKY9-1", "A0AAA9S472-1", "F1MN35-1", "A0AAA9SMH0-1", "A0AAA9RSQ6-1", "F1N2S7-1", "F1N3W6-1", "A0AAA9S5X7-1", "F6QVY2-1", "A0A3Q1NKC2-1", "F1N5U0-1", "A0A3Q1MUZ6-1", "A0AAA9SJ92-1", "A0AAA9U136-1", "A0A3Q1LYH3-1", "A0A3Q1MXI5-1", "A0AAA9TJD5-1", "E1BBM3-1", "E1BEW4-1", "A0AAA9SK35-1", "F1MG29-1", "A0AAA9SGM8-1", "A0AAA9SXE3-1", "P05131-1", "E1BHE1-1", "A0A3Q1LGC2-1", "A0A3Q1NBC4-1", "F6QTX4-1", "A0AAA9SWA1-1", "A0AAA9TDL1-1", "F1MU35-1", "A5D791-1", "F1N664-1", "A0AAA9T3H7-1", "F1MAZ8-1", "F1MH23-1", "A0A3S5ZPR2-1", "F1MWN0-1", "P48734-1", "A0AAA9SNP6-1", "A0AAA9RVB1-1", "A0AAF6Z257-1", "A0A3Q1M614-1", "A0ABI0NQQ4-1", "E1BEI6-1", "F1N332-1", "A7MB74-1", "Q3SZJ2-1", "F1MXH6-1", "Q5E9L6-1", "A0AAF6YHL8-1", "Q08DZ2-1", "A0A3Q1LR28-1", "Q3MHJ9-1", "P00517-1", "Q3SYZ2-1", "A2VDU3-1", "P67827-1", "P05126-1", "F6RPH3-1", "A0AAA9T5C9-1", "Q3SWY6-1", "A7E3S4-1", "A1A4I4-1", "F1MI60-1", "E1BK52-1", "Q5E9X2-1", "Q17R13-1", "P68399-1", "F6Q6K1-1", "A0ABI0P0X3-1", "A0AAA9TNL3-1", "A0AAA9S4Z4-1", "F6PN06-1", "E1B8P9-1", "Q2HJF7-1", "A0AAA9S9A9-1", "E1BG90-1", "F1MGX2-1", "A0A3Q1M4X3-1", "E1BN63-1", "A0A3Q1LNU2-1", "F1MKK7-1", "A0AAA9SMT9-1", "A0A3Q1MKC7-1", "A0A3Q1LTC6-1", "A0AAA9TD48-1", "A0A3Q1MEZ6-1", "E1BPU0-1", "A0A3Q1N707-1", "A0A3Q1LNA9-1", "F1MBN7-1", "E1BJM5-1", "F1MFK1-1", "A0A3Q1LKG0-1", "Q1RMT7-1", "G5E5D4-1", "F1MYV9-1", "A0AAA9T584-1", "A0AAA9SLY1-1", "Q2TA06-1", "Q5E9Y0-1", "A0AAA9RWB8-1", "A0AAA9SX77-1", "A0A3Q1MRR6-1", "A0A3Q1N9F5-1", "A2VDV2-1", "A2VDZ4-1", "A5PKJ4-1", "E1BB50-1", "E1BB52-1", "F1MH24-1", "E1BCU9-1", "E1BFR5-1", "F1MDC9-1", "F1MNP4-1", "F1MQ96-1", "A0AAA9SU81-1", "P00516-1", "A0A3Q1LJU7-1", "A0A3Q1MS69-1", "A0A3Q1LU59-1", "A0A3Q1N4A7-1", "F1MY82-1", "F6RP02-1", "A7MBB4-1", "E1BMN8-1", "Q32KY4-1", "Q32PI1-1", "Q4TVR5-1", "Q5EAB2-1", "Q6TJY3-1", "E1B7H4-1", "E1BJ19-1", "E1BP01-1", "A0AAA9T940-1", "F1MC61-1", "E1BC64-1", "E1BNS8-1", "F1MPF0-1", "G5E518-1", "Q7YRC6-1", "Q95KV0-1", "Q9N0P9-1", "P20427-1", "P35507-1", "P35509-1", "P35508-1", "P46196-1", "P04409-1", "P05128-1", "H2XJE9-1", "Q0VD22-1", "Q2TBL8-1", "Q32L23-1", "Q3SX21-1", "Q3SZW1-1", "Q01314-1", "Q02399-1", "Q08E52-1", "Q0V7M1-1", "Q1RMT8-1", "Q2KIP2-1", "Q2LGB3-1", "Q2TA25-1", "Q3T0N5-1", "A0A3Q1LM61-1", "A0A3Q1LRM6-1", "E1BPB5-1", "A0A3Q1MHH5-1", "A0A3Q1M4N6-1", "G3MX00-1", "F1MH45-1", "A0A3Q1M334-1", "A0A3Q1M9L7-1", "A0A3Q1MA37-1", "A0A3Q1MHL3-1", "E1BP72-1", "A0AAA9T7Z7-1", "Q58D94-1", "F1MJ55-1", "E1BI47-1", "Q17QV9-1", "F1N6C1-1", "G3N2F6-1", "A0AAA9T3K7-1", "F1MPI8-1", "F1MVV5-1", "F6RD87-1", "G3N2D2-1", "G5E577-1", "E1B887-1", "E1B902-1", "E1BAL6-1", "E1BH31-1", "E1BJH5-1", "E1BK33-1", "F1MG77-1", "F1MKW8-1", "A0AAA9SJQ0-1", "E1BL08-1", "E1B793-1", "E1B7L9-1", "E1B9B6-1", "E1BFV2-1", "A0AAA9T042-1", "A0AAA9TU12-1", "A0AAA9T593-1", "A0A3Q1MI36-1", "A0AAA9RSJ2-1", "A0A3Q1NFM1-1", "A0AAA9T7I8-1", "A0A3Q1LWT7-1", "A0AAA9S954-1", "E1B9F9-1", "A0AAA9RWC6-1", "F6RLA2-1", "E1BCH5-1", "H2XJE8-1", "A0A3Q1LL42-1", "A0AAA9SVM5-1", "F1MYG2-1", "A0A3Q1LLH8-1", "A0A3Q1LN49-1", "A0A3Q1M5T5-1", "A0A3Q1LW88-1", "A0ABI0P2C0-1", "A0AAA9SG01-1", "E1BC36-1", "E1BB49-1", "E1BDG4-1", "E1BKX9-1", "E1BM19-1", "E1BQ34-1", "A0ABI0P443-1", "A0A3Q1LQP3-1", "A0A3Q1MNB4-1", "A0AAA9TWW0-1", "E1BGV8-1", "A0AAA9SIK7-1", "A0AAA9T8Z3-1", "F1N063-1", "A0A3Q1MD82-1", "F1N5K1-1", "E1BN72-1", "F1MLY7-1", "A0AAA9TVT5-1", "A0AAA9SKK8-1", "A0AAA9TNE6-1", "F1MWP1-1", "G3N022-1", "A0A3Q1MLK5-1", "A0AAA9TCI9-1", "F1MC27-1", "A0AAA9RW51-1", "A0AAA9TLV0-1", "E1B8J7-1", "F1MIB2-1", "E1B827-1", "A0A3Q1M1Z0-1", "G3N2J4-1", "F1MSV4-1", "E1B9Q2-1", "A0ABI0NJ75-1", "A0A3Q1M2U5-1", "A0A3Q1LLF0-1", "A0A3Q1M6N5-1", "A0AAF6DLR2-1", "A0ABI0NV47-1", "E1BPP1-1", "E1BC69-1", "E1BCC3-1", "F1MF36-1", "A0AAA9SH90-1", "E1BLQ5-1", "F1MG35-1", "F1MSI1-1", "F1MSX4-1", "F1MVR0-1", "F1MY55-1", "G5E5A0-1", "F1MUU2-1", "F1MY86-1", "A0AAA9SJA3-1", "F6Q5Z6-1", "A0AAA9TP92-1", "A0AAA9S2N3-1", "A0A3Q1MHM3-1", "F6QY93-1", "F6Q5B6-1", "A0AAA9SYW5-1", "A0A3Q1LH95-1", "A0AAF6DMH7-1", "A0AAF6YMX3-1", "F6Q9U9-1", "A0A3Q1MW77-1", "F1MF50-1", "P52175-1", "Q8MIT6-1", "Q28021-1", "A0ABI0NRQ5-1", "F1MDS3-1", "F1MM88-1", "A0ABI0NM98-1", "A0ABI0NS30-1", "A0ABI0P3N8-1" ], "evidence": [ { "id": "46608", "database": "Rhea", "url": "https://www.rhea-db.org/rhea/46608" } ] } ], "reaction_participants": [], "reaction_enzymes": [ { "uniprot_ac": "A0A3Q1LGC2", "gene_name": "HUNK", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A3Q1LGC2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1LGC2" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A3Q1LGC2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1LGC2" } ] } ] }, { "uniprot_ac": "A0A3Q1LH95", "gene_name": "MAP3K20", "activity": [ { "ec_number": "2.7.11.25", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A3Q1LH95", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1LH95" } ] }, { "ec_number": "2.7.11.25", "activity": "", "evidence": [ { "id": "A0A3Q1LH95", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1LH95" } ] } ] }, { "uniprot_ac": "A0A3Q1LJU7", "gene_name": "MAPK9", "activity": [ { "ec_number": "2.7.11.24", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A3Q1LJU7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1LJU7" } ] }, { "ec_number": "2.7.11.24", "activity": "", "evidence": [ { "id": "A0A3Q1LJU7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1LJU7" } ] } ] }, { "uniprot_ac": "A0A3Q1LKG0", "gene_name": "MINK1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A3Q1LKG0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1LKG0" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A3Q1LKG0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1LKG0" } ] } ] }, { "uniprot_ac": "A0A3Q1LL42", "gene_name": "SBK2", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A3Q1LL42", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1LL42" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A3Q1LL42", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1LL42" } ] } ] }, { "uniprot_ac": "A0A3Q1LLF0", "gene_name": "PIK3R4", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A3Q1LLF0", "database": 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"https://www.uniprot.org/uniprotkb/A0A3Q1LM61" } ] }, { "ec_number": "2.7.11.13", "activity": "", "evidence": [ { "id": "A0A3Q1LM61", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1LM61" } ] } ] }, { "uniprot_ac": "A0A3Q1LN49", "gene_name": "CDK17", "activity": [ { "ec_number": "2.7.11.22", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A3Q1LN49", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1LN49" } ] }, { "ec_number": "2.7.11.22", "activity": "", "evidence": [ { "id": "A0A3Q1LN49", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1LN49" } ] } ] }, { "uniprot_ac": "A0A3Q1LNA9", "gene_name": "PAK3", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A3Q1LNA9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1LNA9" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A3Q1LNA9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1LNA9" } ] } ] }, { "uniprot_ac": "A0A3Q1LNU2", "gene_name": "DYRK1A", "activity": [ { "ec_number": "2.7.11.23", "activity": "[DNA-directed RNA polymerase] + ATP = phospho-[DNA-directed RNA polymerase] + ADP + H(+).", "evidence": [ { "id": "A0A3Q1LNU2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1LNU2" } ] }, { "ec_number": "2.7.12.1", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A3Q1LNU2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1LNU2" } ] }, { "ec_number": "2.7.11.23", "activity": "", "evidence": [ { "id": "A0A3Q1LNU2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1LNU2" } ] }, { "ec_number": "2.7.12.1", "activity": "", "evidence": [ { "id": "A0A3Q1LNU2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1LNU2" } ] } ] }, { "uniprot_ac": "A0A3Q1LQP3", "gene_name": "KSR1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A3Q1LQP3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1LQP3" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A3Q1LQP3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1LQP3" } ] } ] }, { "uniprot_ac": "A0A3Q1LR28", "gene_name": "TESK2", "activity": [ { "ec_number": "2.7.12.1", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A3Q1LR28", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1LR28" } ] }, { "ec_number": "2.7.12.1", "activity": "", "evidence": [ { "id": "A0A3Q1LR28", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1LR28" } ] } ] }, { "uniprot_ac": "A0A3Q1LRM6", "gene_name": "MAPK10", "activity": [ { "ec_number": "2.7.11.24", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A3Q1LRM6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1LRM6" } ] }, { "ec_number": "2.7.11.24", "activity": "", "evidence": [ { "id": "A0A3Q1LRM6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1LRM6" } ] } ] }, { "uniprot_ac": "A0A3Q1LTC6", "gene_name": "MAP2K4", "activity": [ { "ec_number": "2.7.12.2", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A3Q1LTC6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1LTC6" } ] }, { "ec_number": "2.7.12.2", "activity": "", "evidence": [ { "id": "A0A3Q1LTC6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1LTC6" } ] } ] }, { "uniprot_ac": "A0A3Q1LU59", "gene_name": "MAPK15", "activity": [ { "ec_number": "2.7.11.24", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A3Q1LU59", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1LU59" } ] }, { "ec_number": "2.7.11.24", "activity": "", "evidence": [ { "id": "A0A3Q1LU59", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1LU59" } ] } ] }, { "uniprot_ac": "A0A3Q1LW88", "gene_name": "DCAF1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A3Q1LW88", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1LW88" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A3Q1LW88", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1LW88" } ] } ] }, { "uniprot_ac": "A0A3Q1LWT7", "gene_name": "CAMKK2", "activity": [ { "ec_number": "2.7.11.17", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A3Q1LWT7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1LWT7" } ] }, { "ec_number": "2.7.11.17", "activity": "", "evidence": [ { "id": "A0A3Q1LWT7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1LWT7" } ] } ] }, { "uniprot_ac": "A0A3Q1LYH3", "gene_name": "RPS6KA2", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A3Q1LYH3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1LYH3" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A3Q1LYH3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1LYH3" } ] } ] }, { "uniprot_ac": "A0A3Q1M1Z0", "gene_name": "ULK4", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + 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"ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A3Q1M614", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1M614" } ] } ] }, { "uniprot_ac": "A0A3Q1M6N5", "gene_name": "BMP2K", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A3Q1M6N5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1M6N5" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A3Q1M6N5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1M6N5" } ] } ] }, { "uniprot_ac": "A0A3Q1M9F0", "gene_name": "MAST3", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A3Q1M9F0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1M9F0" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": 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"uniprot_ac": "A0A3Q1MHH5", "gene_name": "MAP3K9", "activity": [ { "ec_number": "2.7.11.25", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A3Q1MHH5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1MHH5" } ] }, { "ec_number": "2.7.11.25", "activity": "", "evidence": [ { "id": "A0A3Q1MHH5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1MHH5" } ] } ] }, { "uniprot_ac": "A0A3Q1MHL3", "gene_name": "LIMK2", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A3Q1MHL3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1MHL3" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A3Q1MHL3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1MHL3" } ] } ] }, { "uniprot_ac": "A0A3Q1MHM3", "gene_name": "HIPK2", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A3Q1MHM3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1MHM3" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A3Q1MHM3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1MHM3" } ] } ] }, { "uniprot_ac": "A0A3Q1MI36", "gene_name": "", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A3Q1MI36", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1MI36" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A3Q1MI36", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1MI36" } ] } ] }, { "uniprot_ac": "A0A3Q1MKC7", "gene_name": "CAMK2A", "activity": [ { "ec_number": "2.7.11.17", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A3Q1MKC7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1MKC7" } ] }, { "ec_number": "2.7.11.17", "activity": "", "evidence": [ { "id": "A0A3Q1MKC7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1MKC7" } ] } ] }, { "uniprot_ac": "A0A3Q1MLK5", "gene_name": "LMTK2", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A3Q1MLK5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1MLK5" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A3Q1MLK5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1MLK5" } ] } ] }, { "uniprot_ac": "A0A3Q1MNB4", "gene_name": "STK32A", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A3Q1MNB4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1MNB4" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A3Q1MNB4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1MNB4" } ] } ] }, { "uniprot_ac": "A0A3Q1MRR6", "gene_name": "PRKCD", "activity": [ { "ec_number": "2.7.11.13", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A3Q1MRR6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1MRR6" } ] }, { "ec_number": "2.7.11.13", "activity": "", "evidence": [ { "id": "A0A3Q1MRR6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1MRR6" } ] } ] }, { "uniprot_ac": "A0A3Q1MRW3", "gene_name": "SNRK", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A3Q1MRW3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1MRW3" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A3Q1MRW3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1MRW3" } ] } ] }, { "uniprot_ac": "A0A3Q1MS69", "gene_name": "NEK2", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A3Q1MS69", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1MS69" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A3Q1MS69", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1MS69" } ] } ] }, { "uniprot_ac": "A0A3Q1MUZ6", "gene_name": "MARK4", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A3Q1MUZ6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1MUZ6" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A3Q1MUZ6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1MUZ6" } ] } ] }, { "uniprot_ac": "A0A3Q1MW77", "gene_name": "ROCK2", "activity": [ { "ec_number": "2.7.11.39", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A3Q1MW77", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1MW77" } ] }, { "ec_number": "2.7.11.39", "activity": "", "evidence": [ { "id": "A0A3Q1MW77", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1MW77" } ] } ] }, { "uniprot_ac": "A0A3Q1MXI5", "gene_name": "DAPK1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A3Q1MXI5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1MXI5" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A3Q1MXI5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1MXI5" } ] } ] }, { "uniprot_ac": "A0A3Q1N4A7", "gene_name": "CIT", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A3Q1N4A7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1N4A7" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A3Q1N4A7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1N4A7" } ] } ] }, { "uniprot_ac": "A0A3Q1N707", "gene_name": "WNK4", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A3Q1N707", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1N707" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A3Q1N707", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1N707" } ] } ] }, { "uniprot_ac": "A0A3Q1N860", "gene_name": "RPS6KL1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A3Q1N860", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1N860" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A3Q1N860", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1N860" } ] } ] }, { "uniprot_ac": "A0A3Q1N9F5", "gene_name": "PRKD1", "activity": [ { "ec_number": "2.7.11.13", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A3Q1N9F5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1N9F5" } ] }, { "ec_number": "2.7.11.13", "activity": "", "evidence": [ { "id": "A0A3Q1N9F5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1N9F5" } ] } ] }, { "uniprot_ac": "A0A3Q1NBC4", "gene_name": "SRPK2", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A3Q1NBC4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1NBC4" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A3Q1NBC4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1NBC4" } ] } ] }, { "uniprot_ac": "A0A3Q1NFM1", "gene_name": "LOC100138998", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A3Q1NFM1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1NFM1" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A3Q1NFM1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1NFM1" } ] } ] }, { "uniprot_ac": "A0A3Q1NKC2", "gene_name": "CAMK2G", "activity": [ { "ec_number": "2.7.11.17", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A3Q1NKC2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1NKC2" } ] }, { "ec_number": "2.7.11.17", "activity": "", "evidence": [ { "id": "A0A3Q1NKC2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1NKC2" } ] } ] }, { "uniprot_ac": "A0A3S5ZPR2", "gene_name": "MELK", "activity": [ { "ec_number": "2.7.10.2", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A3S5ZPR2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3S5ZPR2" } ] }, { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A3S5ZPR2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3S5ZPR2" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A3S5ZPR2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3S5ZPR2" } ] }, { "ec_number": "2.7.10.2", "activity": "", "evidence": [ { "id": "A0A3S5ZPR2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3S5ZPR2" } ] } ] }, { "uniprot_ac": "A0AAA9RSJ2", "gene_name": "MKNK2", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0AAA9RSJ2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9RSJ2" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0AAA9RSJ2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9RSJ2" } ] } ] }, { "uniprot_ac": "A0AAA9RSQ6", "gene_name": "TRPM6", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0AAA9RSQ6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9RSQ6" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0AAA9RSQ6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9RSQ6" } ] } ] }, { "uniprot_ac": "A0AAA9RTJ4", "gene_name": "PIKFYVE", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0AAA9RTJ4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9RTJ4" } ] }, { "ec_number": "2.7.1.150", "activity": "a 1,2-diacyl-sn-glycero-3-phospho-(1D-myo-inositol-3-phosphate) + ATP = a 1,2-diacyl-sn-glycero-3-phospho-(1D-myo-inositol-3,5-bisphosphate) + ADP + H(+).", "evidence": [ { "id": "A0AAA9RTJ4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9RTJ4" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0AAA9RTJ4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9RTJ4" } ] }, { "ec_number": "2.7.1.150", "activity": "", "evidence": [ { "id": "A0AAA9RTJ4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9RTJ4" } ] } ] }, { "uniprot_ac": "A0AAA9RVB1", "gene_name": "TAOK2", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0AAA9RVB1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9RVB1" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0AAA9RVB1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9RVB1" } ] } ] }, { "uniprot_ac": "A0AAA9RW51", "gene_name": "AATK", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0AAA9RW51", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9RW51" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0AAA9RW51", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9RW51" } ] } ] }, { "uniprot_ac": "A0AAA9RWB8", "gene_name": "TRIO", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0AAA9RWB8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9RWB8" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0AAA9RWB8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9RWB8" } ] } ] }, { "uniprot_ac": "A0AAA9RWC6", "gene_name": "CHEK2", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0AAA9RWC6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9RWC6" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0AAA9RWC6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9RWC6" } ] } ] }, { "uniprot_ac": "A0AAA9S2N3", "gene_name": "CDKL4", "activity": [ { "ec_number": "2.7.11.22", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0AAA9S2N3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9S2N3" } ] }, { "ec_number": "2.7.11.22", "activity": "", "evidence": [ { "id": "A0AAA9S2N3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9S2N3" } ] } ] }, { "uniprot_ac": "A0AAA9S472", "gene_name": "MAPK8", "activity": [ { "ec_number": "2.7.11.24", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0AAA9S472", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9S472" } ] }, { "ec_number": "2.7.11.24", "activity": "", "evidence": [ { "id": "A0AAA9S472", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9S472" } ] } ] }, { "uniprot_ac": "A0AAA9S4Z4", "gene_name": "AKT1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0AAA9S4Z4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9S4Z4" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0AAA9S4Z4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9S4Z4" } ] } ] }, { "uniprot_ac": "A0AAA9S5X7", "gene_name": "AURKB", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0AAA9S5X7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9S5X7" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0AAA9S5X7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9S5X7" } ] } ] }, { "uniprot_ac": "A0AAA9S663", "gene_name": "PDPK1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0AAA9S663", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9S663" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0AAA9S663", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9S663" } ] } ] }, { "uniprot_ac": "A0AAA9S954", "gene_name": "CAMKK1", "activity": [ { "ec_number": "2.7.11.17", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0AAA9S954", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9S954" } ] }, { "ec_number": "2.7.11.17", "activity": "", "evidence": [ { "id": "A0AAA9S954", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9S954" } ] } ] }, { "uniprot_ac": "A0AAA9S9A9", "gene_name": "NEK11", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0AAA9S9A9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9S9A9" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0AAA9S9A9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9S9A9" } ] } ] }, { "uniprot_ac": "A0AAA9SG01", "gene_name": "ERN1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0AAA9SG01", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9SG01" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0AAA9SG01", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9SG01" } ] } ] }, { "uniprot_ac": "A0AAA9SGM8", "gene_name": "MKNK1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0AAA9SGM8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9SGM8" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0AAA9SGM8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9SGM8" } ] } ] }, { "uniprot_ac": "A0AAA9SH90", "gene_name": "DAPK2", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0AAA9SH90", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9SH90" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0AAA9SH90", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9SH90" } ] } ] }, { "uniprot_ac": "A0AAA9SIK7", "gene_name": "NEK10", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0AAA9SIK7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9SIK7" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0AAA9SIK7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9SIK7" } ] } ] }, { "uniprot_ac": "A0AAA9SJ92", "gene_name": "RPS6KA1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0AAA9SJ92", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9SJ92" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0AAA9SJ92", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9SJ92" } ] } ] }, { "uniprot_ac": "A0AAA9SJA3", "gene_name": "TTBK2", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0AAA9SJA3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9SJA3" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0AAA9SJA3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9SJA3" } ] } ] }, { "uniprot_ac": "A0AAA9SJQ0", "gene_name": "RPS6KA4", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0AAA9SJQ0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9SJQ0" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0AAA9SJQ0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9SJQ0" } ] } ] }, { "uniprot_ac": "A0AAA9SK35", "gene_name": "PRKG2", "activity": [ { "ec_number": "2.7.11.12", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0AAA9SK35", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9SK35" } ] }, { "ec_number": "2.7.11.12", "activity": "", "evidence": [ { "id": "A0AAA9SK35", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9SK35" } ] } ] }, { "uniprot_ac": "A0AAA9SKK8", "gene_name": "MAP3K4", "activity": [ { "ec_number": "2.7.11.25", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0AAA9SKK8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9SKK8" } ] }, { "ec_number": "2.7.11.25", "activity": "", "evidence": [ { "id": "A0AAA9SKK8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9SKK8" } ] } ] }, { "uniprot_ac": "A0AAA9SLY1", "gene_name": "NEK5", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0AAA9SLY1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9SLY1" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0AAA9SLY1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9SLY1" } ] } ] }, { "uniprot_ac": "A0AAA9SMH0", "gene_name": "DCLK3", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0AAA9SMH0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9SMH0" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0AAA9SMH0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9SMH0" } ] } ] }, { "uniprot_ac": "A0AAA9SMT9", "gene_name": "MAP3K12", "activity": [ { "ec_number": "2.7.11.25", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0AAA9SMT9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9SMT9" } ] }, { "ec_number": "2.7.11.25", "activity": "", "evidence": [ { "id": "A0AAA9SMT9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9SMT9" } ] } ] }, { "uniprot_ac": "A0AAA9SNP6", "gene_name": "MOS", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0AAA9SNP6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9SNP6" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0AAA9SNP6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9SNP6" } ] } ] }, { "uniprot_ac": "A0AAA9SU81", "gene_name": "PRKAA2", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0AAA9SU81", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9SU81" } ] }, { "ec_number": "2.7.11.31", "activity": "L-seryl-[acetyl-CoA carboxylase] + ATP = O-phospho-L-seryl-[acetyl-CoA carboxylase] + ADP + H(+).", "evidence": [ { "id": "A0AAA9SU81", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9SU81" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0AAA9SU81", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9SU81" } ] }, { "ec_number": "2.7.11.31", "activity": "", "evidence": [ { "id": "A0AAA9SU81", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9SU81" } ] } ] }, { "uniprot_ac": "A0AAA9SVM5", "gene_name": "MAP3K3", "activity": [ { "ec_number": "2.7.11.25", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0AAA9SVM5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9SVM5" } ] }, { "ec_number": "2.7.11.25", "activity": "", "evidence": [ { "id": "A0AAA9SVM5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9SVM5" } ] } ] }, { "uniprot_ac": "A0AAA9SWA1", "gene_name": "STK26", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0AAA9SWA1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9SWA1" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0AAA9SWA1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9SWA1" } ] } ] }, { "uniprot_ac": "A0AAA9SX77", "gene_name": "CDK14", "activity": [ { "ec_number": "2.7.11.22", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0AAA9SX77", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9SX77" } ] }, { "ec_number": "2.7.11.22", "activity": "", "evidence": [ { "id": "A0AAA9SX77", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9SX77" } ] } ] }, { "uniprot_ac": "A0AAA9SXE3", "gene_name": "MAP3K6", "activity": [ { "ec_number": "2.7.11.25", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0AAA9SXE3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9SXE3" } ] }, { "ec_number": "2.7.11.25", "activity": "", "evidence": [ { "id": "A0AAA9SXE3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9SXE3" } ] } ] }, { "uniprot_ac": "A0AAA9SYW5", "gene_name": "NEK3", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0AAA9SYW5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9SYW5" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0AAA9SYW5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9SYW5" } ] } ] }, { "uniprot_ac": "A0AAA9T042", "gene_name": "DYRK4", "activity": [ { "ec_number": "2.7.12.1", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0AAA9T042", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9T042" } ] }, { "ec_number": "2.7.12.1", "activity": "", "evidence": [ { "id": "A0AAA9T042", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9T042" } ] } ] }, { "uniprot_ac": "A0AAA9T2F0", "gene_name": "BRAF", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0AAA9T2F0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9T2F0" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0AAA9T2F0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9T2F0" } ] } ] }, { "uniprot_ac": "A0AAA9T3H7", "gene_name": "TNK1", "activity": [ { "ec_number": "2.7.10.2", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0AAA9T3H7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9T3H7" } ] }, { "ec_number": "2.7.10.2", "activity": "", "evidence": [ { "id": "A0AAA9T3H7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9T3H7" } ] } ] }, { "uniprot_ac": "A0AAA9T3K7", "gene_name": "WNK3", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0AAA9T3K7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9T3K7" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0AAA9T3K7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9T3K7" } ] } ] }, { "uniprot_ac": "A0AAA9T584", "gene_name": "CSNK1G3", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0AAA9T584", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9T584" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0AAA9T584", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9T584" } ] } ] }, { "uniprot_ac": "A0AAA9T593", "gene_name": "SRPK1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0AAA9T593", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9T593" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0AAA9T593", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9T593" } ] } ] }, { "uniprot_ac": "A0AAA9T5C9", "gene_name": "MAPK1", "activity": [ { "ec_number": "2.7.11.24", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0AAA9T5C9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9T5C9" } ] }, { "ec_number": "2.7.11.24", "activity": "", "evidence": [ { "id": "A0AAA9T5C9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9T5C9" } ] } ] }, { "uniprot_ac": "A0AAA9T7I8", "gene_name": "TSSK2", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0AAA9T7I8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9T7I8" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0AAA9T7I8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9T7I8" } ] } ] }, { "uniprot_ac": "A0AAA9T7L6", "gene_name": "RPS6KC1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0AAA9T7L6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9T7L6" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0AAA9T7L6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9T7L6" } ] } ] }, { "uniprot_ac": "A0AAA9T7Z7", "gene_name": "RPS6KA5", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0AAA9T7Z7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9T7Z7" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0AAA9T7Z7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9T7Z7" } ] } ] }, { "uniprot_ac": "A0AAA9T8T9", "gene_name": "MARK2", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0AAA9T8T9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9T8T9" } ] }, { "ec_number": "2.7.11.26", "activity": "L-seryl-[tau protein] + ATP = O-phospho-L-seryl-[tau protein] + ADP + H(+).", "evidence": [ { "id": "A0AAA9T8T9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9T8T9" } ] }, { "ec_number": "2.7.11.26", "activity": "", "evidence": [ { "id": "A0AAA9T8T9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9T8T9" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0AAA9T8T9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9T8T9" } ] } ] }, { "uniprot_ac": "A0AAA9T8Z3", "gene_name": "STK32C", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0AAA9T8Z3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9T8Z3" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0AAA9T8Z3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9T8Z3" } ] } ] }, { "uniprot_ac": "A0AAA9T940", "gene_name": "PLK2", "activity": [ { "ec_number": "2.7.11.21", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0AAA9T940", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9T940" } ] }, { "ec_number": "2.7.11.21", "activity": "", "evidence": [ { "id": "A0AAA9T940", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9T940" } ] } ] }, { "uniprot_ac": "A0AAA9TCI9", "gene_name": "MOK", "activity": [ { "ec_number": "2.7.11.22", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0AAA9TCI9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TCI9" } ] }, { "ec_number": "2.7.11.22", "activity": "", "evidence": [ { "id": "A0AAA9TCI9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TCI9" } ] } ] }, { "uniprot_ac": "A0AAA9TD48", "gene_name": "DYRK1B", "activity": [ { "ec_number": "2.7.12.1", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0AAA9TD48", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TD48" } ] }, { "ec_number": "2.7.12.1", "activity": "", "evidence": [ { "id": "A0AAA9TD48", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TD48" } ] } ] }, { "uniprot_ac": "A0AAA9TDL1", "gene_name": "SBK1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0AAA9TDL1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TDL1" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0AAA9TDL1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TDL1" } ] } ] }, { "uniprot_ac": "A0AAA9TJD5", "gene_name": "", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0AAA9TJD5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TJD5" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0AAA9TJD5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TJD5" } ] } ] }, { "uniprot_ac": "A0AAA9TLV0", "gene_name": "STK32B", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0AAA9TLV0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TLV0" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0AAA9TLV0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TLV0" } ] } ] }, { "uniprot_ac": "A0AAA9TMV7", "gene_name": "SMG1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0AAA9TMV7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TMV7" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0AAA9TMV7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TMV7" } ] } ] }, { "uniprot_ac": "A0AAA9TNE6", "gene_name": "TLK2", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0AAA9TNE6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TNE6" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0AAA9TNE6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TNE6" } ] } ] }, { "uniprot_ac": "A0AAA9TNL3", "gene_name": "SLK", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0AAA9TNL3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TNL3" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0AAA9TNL3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TNL3" } ] } ] }, { "uniprot_ac": "A0AAA9TP92", "gene_name": "CAMK1", "activity": [ { "ec_number": "2.7.11.17", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0AAA9TP92", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TP92" } ] }, { "ec_number": "2.7.11.17", "activity": "", "evidence": [ { "id": "A0AAA9TP92", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TP92" } ] } ] }, { "uniprot_ac": "A0AAA9TU12", "gene_name": "PRKCQ", "activity": [ { "ec_number": "2.7.11.13", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0AAA9TU12", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TU12" } ] }, { "ec_number": "2.7.11.13", "activity": "", "evidence": [ { "id": "A0AAA9TU12", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TU12" } ] } ] }, { "uniprot_ac": "A0AAA9TVT5", "gene_name": "CASK", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0AAA9TVT5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TVT5" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0AAA9TVT5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TVT5" } ] } ] }, { "uniprot_ac": "A0AAA9TWW0", "gene_name": "TBK1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0AAA9TWW0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TWW0" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0AAA9TWW0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TWW0" } ] } ] }, { "uniprot_ac": "A0AAA9U136", "gene_name": "PRKD2", "activity": [ { "ec_number": "2.7.11.13", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0AAA9U136", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9U136" } ] }, { "ec_number": "2.7.11.13", "activity": "", "evidence": [ { "id": "A0AAA9U136", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9U136" } ] } ] }, { "uniprot_ac": "A0AAA9U1A4", "gene_name": "NUAK2", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0AAA9U1A4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9U1A4" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0AAA9U1A4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9U1A4" } ] } ] }, { "uniprot_ac": "A0AAA9U1M9", "gene_name": "DMPK", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0AAA9U1M9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9U1M9" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0AAA9U1M9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9U1M9" } ] } ] }, { "uniprot_ac": "A0AAA9U1R3", "gene_name": "DCLK2", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0AAA9U1R3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9U1R3" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0AAA9U1R3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9U1R3" } ] } ] }, { "uniprot_ac": "A0AAF6DLR2", "gene_name": "CDK18", "activity": [ { "ec_number": "2.7.11.22", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0AAF6DLR2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAF6DLR2" } ] }, { "ec_number": "2.7.11.22", "activity": "", "evidence": [ { "id": "A0AAF6DLR2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAF6DLR2" } ] } ] }, { "uniprot_ac": "A0AAF6DMH7", "gene_name": "RIPK1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0AAF6DMH7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAF6DMH7" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0AAF6DMH7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAF6DMH7" } ] } ] }, { "uniprot_ac": "A0AAF6YHL8", "gene_name": "MAPK7", "activity": [ { "ec_number": "2.7.11.24", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0AAF6YHL8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAF6YHL8" } ] }, { "ec_number": "2.7.11.24", "activity": "", "evidence": [ { "id": "A0AAF6YHL8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAF6YHL8" } ] } ] }, { "uniprot_ac": "A0AAF6YMX3", "gene_name": "CDK9", "activity": [ { "ec_number": "2.7.11.22", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0AAF6YMX3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAF6YMX3" } ] }, { "ec_number": "2.7.11.23", "activity": "[DNA-directed RNA polymerase] + ATP = phospho-[DNA-directed RNA polymerase] + ADP + H(+).", "evidence": [ { "id": "A0AAF6YMX3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAF6YMX3" } ] }, { "ec_number": "2.7.11.22", "activity": "", "evidence": [ { "id": "A0AAF6YMX3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAF6YMX3" } ] }, { "ec_number": "2.7.11.23", "activity": "", "evidence": [ { "id": "A0AAF6YMX3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAF6YMX3" } ] } ] }, { "uniprot_ac": "A0AAF6Z257", "gene_name": "IRAK1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0AAF6Z257", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAF6Z257" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0AAF6Z257", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAF6Z257" } ] } ] }, { "uniprot_ac": "A0ABI0NJ75", "gene_name": "PAK6", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0ABI0NJ75", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NJ75" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0ABI0NJ75", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NJ75" } ] } ] }, { "uniprot_ac": "A0ABI0NM98", "gene_name": "KALRN", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0ABI0NM98", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NM98" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0ABI0NM98", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NM98" } ] } ] }, { "uniprot_ac": "A0ABI0NMT8", "gene_name": "PIK3CG", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0ABI0NMT8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NMT8" } ] }, { "ec_number": "2.7.1.153", "activity": "a 1,2-diacyl-sn-glycero-3-phospho-(1D-myo-inositol-4,5-bisphosphate) + ATP = a 1,2-diacyl-sn-glycero-3-phospho-(1D-myo-inositol-3,4,5-trisphosphate) + ADP + H(+).", "evidence": [ { "id": "A0ABI0NMT8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NMT8" } ] }, { "ec_number": "2.7.1.137", "activity": "a 1,2-diacyl-sn-glycero-3-phospho-(1D-myo-inositol) + ATP = a 1,2-diacyl-sn-glycero-3-phospho-(1D-myo-inositol-3-phosphate) + ADP + H(+).", "evidence": [ { "id": "A0ABI0NMT8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NMT8" } ] }, { "ec_number": "2.7.1.154", "activity": "a 1,2-diacyl-sn-glycero-3-phospho-(1D-myo-inositol 4-phosphate) + ATP = a 1,2-diacyl-sn-glycero-3-phospho-(1D-myo-inositol-3,4-bisphosphate) + ADP + H(+).", "evidence": [ { "id": "A0ABI0NMT8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NMT8" } ] }, { "ec_number": "2.7.1.153", "activity": "", "evidence": [ { "id": "A0ABI0NMT8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NMT8" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0ABI0NMT8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NMT8" } ] }, { "ec_number": "2.7.1.137", "activity": "", "evidence": [ { "id": "A0ABI0NMT8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NMT8" } ] }, { "ec_number": "2.7.1.154", "activity": "", "evidence": [ { "id": "A0ABI0NMT8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NMT8" } ] } ] }, { "uniprot_ac": "A0ABI0NQQ4", "gene_name": "PRKAA1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0ABI0NQQ4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NQQ4" } ] }, { "ec_number": "2.7.11.26", "activity": "L-seryl-[tau protein] + ATP = O-phospho-L-seryl-[tau protein] + ADP + H(+).", "evidence": [ { "id": "A0ABI0NQQ4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NQQ4" } ] }, { "ec_number": "2.7.11.31", "activity": "L-seryl-[acetyl-CoA carboxylase] + ATP = O-phospho-L-seryl-[acetyl-CoA carboxylase] + ADP + H(+).", "evidence": [ { "id": "A0ABI0NQQ4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NQQ4" } ] }, { "ec_number": "2.7.11.26", "activity": "", "evidence": [ { "id": "A0ABI0NQQ4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NQQ4" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0ABI0NQQ4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NQQ4" } ] }, { "ec_number": "2.7.11.31", "activity": "", "evidence": [ { "id": "A0ABI0NQQ4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NQQ4" } ] } ] }, { "uniprot_ac": "A0ABI0NRQ5", "gene_name": "LOC101905399", "activity": [ { "ec_number": "2.7.12.2", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0ABI0NRQ5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NRQ5" } ] }, { "ec_number": "2.7.12.2", "activity": "", "evidence": [ { "id": "A0ABI0NRQ5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NRQ5" } ] } ] }, { "uniprot_ac": "A0ABI0NS30", "gene_name": "PRKCA", "activity": [ { "ec_number": "2.7.11.13", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0ABI0NS30", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NS30" } ] }, { "ec_number": "2.7.11.13", "activity": "", "evidence": [ { "id": "A0ABI0NS30", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NS30" } ] } ] }, { "uniprot_ac": "A0ABI0NV47", "gene_name": "DCLK1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0ABI0NV47", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NV47" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0ABI0NV47", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NV47" } ] } ] }, { "uniprot_ac": "A0ABI0P0X3", "gene_name": "", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0ABI0P0X3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0ABI0P0X3" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0ABI0P0X3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0ABI0P0X3" } ] } ] }, { "uniprot_ac": "A0ABI0P2C0", "gene_name": "TSSK5", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0ABI0P2C0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0ABI0P2C0" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0ABI0P2C0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0ABI0P2C0" } ] } ] }, { "uniprot_ac": "A0ABI0P3N8", "gene_name": "", "activity": [ { "ec_number": "2.7.11.22", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0ABI0P3N8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0ABI0P3N8" } ] }, { "ec_number": "2.7.11.22", "activity": "", "evidence": [ { "id": "A0ABI0P3N8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0ABI0P3N8" } ] } ] }, { "uniprot_ac": "A0ABI0P3P6", "gene_name": "MAST4", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0ABI0P3P6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0ABI0P3P6" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0ABI0P3P6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0ABI0P3P6" } ] } ] }, { "uniprot_ac": "A0ABI0P443", "gene_name": "SGK2", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0ABI0P443", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0ABI0P443" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0ABI0P443", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0ABI0P443" } ] } ] }, { "uniprot_ac": "A1A4I4", "gene_name": "PKN1", "activity": [ { "ec_number": "2.7.11.13", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A1A4I4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A1A4I4" } ] }, { "ec_number": "2.7.11.13", "activity": "", "evidence": [ { "id": "A1A4I4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A1A4I4" } ] } ] }, { "uniprot_ac": "A2VDU3", "gene_name": "MAP3K7", "activity": [ { "ec_number": "2.7.11.25", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A2VDU3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A2VDU3" } ] }, { "ec_number": "2.7.11.25", "activity": "", "evidence": [ { "id": "A2VDU3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A2VDU3" } ] } ] }, { "uniprot_ac": "A2VDV2", "gene_name": "STK38", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A2VDV2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A2VDV2" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A2VDV2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A2VDV2" } ] } ] }, { "uniprot_ac": "A2VDZ4", "gene_name": "PLK4", "activity": [ { "ec_number": "2.7.11.21", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A2VDZ4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A2VDZ4" } ] }, { "ec_number": "2.7.11.21", "activity": "", "evidence": [ { "id": "A2VDZ4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A2VDZ4" } ] } ] }, { "uniprot_ac": "A5D791", "gene_name": "EIF2AK3", "activity": [ { "ec_number": "2.7.10.2", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "A5D791", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A5D791" } ] }, { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A5D791", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A5D791" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A5D791", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A5D791" } ] } ] }, { "uniprot_ac": "A5PKJ4", "gene_name": "MAPK7", "activity": [ { "ec_number": "2.7.11.24", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A5PKJ4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A5PKJ4" } ] }, { "ec_number": "2.7.11.24", "activity": "", "evidence": [ { "id": "A5PKJ4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A5PKJ4" } ] } ] }, { "uniprot_ac": "A7E3S4", "gene_name": "RAF1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A7E3S4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A7E3S4" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A7E3S4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A7E3S4" } ] } ] }, { "uniprot_ac": "A7E3X2", "gene_name": "CSNK1G1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A7E3X2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A7E3X2" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A7E3X2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A7E3X2" } ] } ] }, { "uniprot_ac": "A7MB74", "gene_name": "SGK1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A7MB74", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A7MB74" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A7MB74", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A7MB74" } ] } ] }, { "uniprot_ac": "A7MBB4", "gene_name": "MAP3K13", "activity": [ { "ec_number": "2.7.11.25", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A7MBB4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A7MBB4" } ] }, { "ec_number": "2.7.11.25", "activity": "", "evidence": [ { "id": "A7MBB4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A7MBB4" } ] } ] }, { "uniprot_ac": "E1B754", "gene_name": "MAST2", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "E1B754", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1B754" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "E1B754", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1B754" } ] } ] }, { "uniprot_ac": "E1B793", "gene_name": "STK36", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "E1B793", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1B793" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "E1B793", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1B793" } ] } ] }, { "uniprot_ac": "E1B7H4", "gene_name": "MAP3K10", "activity": [ { "ec_number": "2.7.11.25", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "E1B7H4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1B7H4" } ] }, { "ec_number": "2.7.11.25", "activity": "", "evidence": [ { "id": "E1B7H4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1B7H4" } ] } ] }, { "uniprot_ac": "E1B7L9", "gene_name": "PRKD3", "activity": [ { "ec_number": "2.7.11.13", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "E1B7L9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1B7L9" } ] }, { "ec_number": "2.7.11.13", "activity": "", "evidence": [ { "id": "E1B7L9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1B7L9" } ] } ] }, { "uniprot_ac": "E1B827", "gene_name": "NEK8", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "E1B827", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1B827" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "E1B827", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1B827" } ] } ] }, { "uniprot_ac": "E1B887", "gene_name": "RIOK1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "E1B887", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1B887" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "E1B887", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1B887" } ] } ] }, { "uniprot_ac": "E1B8J7", "gene_name": "ERN2", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "E1B8J7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1B8J7" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "E1B8J7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1B8J7" } ] } ] }, { "uniprot_ac": "E1B8P9", "gene_name": "MAPK3", "activity": [ { "ec_number": "2.7.11.24", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "E1B8P9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1B8P9" } ] }, { "ec_number": "2.7.11.24", "activity": "", "evidence": [ { "id": "E1B8P9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1B8P9" } ] } ] }, { "uniprot_ac": "E1B902", "gene_name": "MAP4K2", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "E1B902", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1B902" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "E1B902", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1B902" } ] } ] }, { "uniprot_ac": "E1B9B6", "gene_name": "NUAK1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "E1B9B6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1B9B6" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "E1B9B6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1B9B6" } ] } ] }, { "uniprot_ac": "E1B9F9", "gene_name": "LATS2", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "E1B9F9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1B9F9" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "E1B9F9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1B9F9" } ] } ] }, { "uniprot_ac": "E1B9Q2", "gene_name": "CLK2", "activity": [ { "ec_number": "2.7.12.1", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "E1B9Q2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1B9Q2" } ] }, { "ec_number": "2.7.12.1", "activity": "", "evidence": [ { "id": "E1B9Q2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1B9Q2" } ] } ] }, { "uniprot_ac": "E1BAL6", "gene_name": "EIF2AK4", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "E1BAL6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BAL6" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "E1BAL6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BAL6" } ] } ] }, { "uniprot_ac": "E1BB49", "gene_name": "HIPK4", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "E1BB49", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BB49" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "E1BB49", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BB49" } ] } ] }, { "uniprot_ac": "E1BB50", "gene_name": "CDK12", "activity": [ { "ec_number": "2.7.11.22", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "E1BB50", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BB50" } ] }, { "ec_number": "2.7.11.23", "activity": "[DNA-directed RNA polymerase] + ATP = phospho-[DNA-directed RNA polymerase] + ADP + H(+).", "evidence": [ { "id": "E1BB50", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BB50" } ] }, { "ec_number": "2.7.11.23", "activity": "", "evidence": [ { "id": "E1BB50", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BB50" } ] }, { "ec_number": "2.7.11.22", "activity": "", "evidence": [ { "id": "E1BB50", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BB50" } ] } ] }, { "uniprot_ac": "E1BB52", "gene_name": "CDK13", "activity": [ { "ec_number": "2.7.11.22", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "E1BB52", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BB52" } ] }, { "ec_number": "2.7.11.23", "activity": "[DNA-directed RNA polymerase] + ATP = phospho-[DNA-directed RNA polymerase] + ADP + H(+).", "evidence": [ { "id": "E1BB52", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BB52" } ] }, { "ec_number": "2.7.11.23", "activity": "", "evidence": [ { "id": "E1BB52", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BB52" } ] }, { "ec_number": "2.7.11.22", "activity": "", "evidence": [ { "id": "E1BB52", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BB52" } ] } ] }, { "uniprot_ac": "E1BBM3", "gene_name": "NEK1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "E1BBM3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BBM3" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "E1BBM3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BBM3" } ] } ] }, { "uniprot_ac": "E1BC36", "gene_name": "CDK6", "activity": [ { "ec_number": "2.7.11.22", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "E1BC36", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BC36" } ] }, { "ec_number": "2.7.11.22", "activity": "", "evidence": [ { "id": "E1BC36", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BC36" } ] } ] }, { "uniprot_ac": "E1BC64", "gene_name": "LIMK1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "E1BC64", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BC64" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "E1BC64", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BC64" } ] } ] }, { "uniprot_ac": "E1BC69", "gene_name": "HIPK3", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "E1BC69", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BC69" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "E1BC69", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BC69" } ] } ] }, { "uniprot_ac": "E1BCC3", "gene_name": "UHMK1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "E1BCC3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BCC3" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "E1BCC3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BCC3" } ] } ] }, { "uniprot_ac": "E1BCH5", "gene_name": "LATS1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "E1BCH5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BCH5" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "E1BCH5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BCH5" } ] } ] }, { "uniprot_ac": "E1BCU9", "gene_name": "STK11", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "E1BCU9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BCU9" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "E1BCU9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BCU9" } ] } ] }, { "uniprot_ac": "E1BDG4", "gene_name": "MAK", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "E1BDG4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BDG4" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "E1BDG4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BDG4" } ] } ] }, { "uniprot_ac": "E1BEI6", "gene_name": "ATM", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "E1BEI6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BEI6" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "E1BEI6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BEI6" } ] } ] }, { "uniprot_ac": "E1BEW4", "gene_name": "LOC613515", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "E1BEW4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BEW4" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "E1BEW4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BEW4" } ] } ] }, { "uniprot_ac": "E1BFR5", "gene_name": "MASTL", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "E1BFR5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BFR5" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "E1BFR5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BFR5" } ] } ] }, { "uniprot_ac": "E1BFV2", "gene_name": "MAP3K21", "activity": [ { "ec_number": "2.7.11.25", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "E1BFV2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BFV2" } ] }, { "ec_number": "2.7.11.25", "activity": "", "evidence": [ { "id": "E1BFV2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BFV2" } ] } ] }, { "uniprot_ac": "E1BG90", "gene_name": "DYRK2", "activity": [ { "ec_number": "2.7.12.1", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "E1BG90", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BG90" } ] }, { "ec_number": "2.7.12.1", "activity": "", "evidence": [ { "id": "E1BG90", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BG90" } ] } ] }, { "uniprot_ac": "E1BGV8", "gene_name": "MAP3K19", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "E1BGV8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BGV8" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "E1BGV8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BGV8" } ] } ] }, { "uniprot_ac": "E1BH31", "gene_name": "MAP4K1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "E1BH31", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BH31" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "E1BH31", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BH31" } ] } ] }, { "uniprot_ac": "E1BHE1", "gene_name": "TAOK3", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "E1BHE1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BHE1" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "E1BHE1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BHE1" } ] } ] }, { "uniprot_ac": "E1BI01", "gene_name": "MAP2K5", "activity": [ { "ec_number": "2.7.12.2", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "E1BI01", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BI01" } ] }, { "ec_number": "2.7.12.2", "activity": "", "evidence": [ { "id": "E1BI01", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BI01" } ] } ] }, { "uniprot_ac": "E1BI47", "gene_name": "PLK5", "activity": [ { "ec_number": "2.7.11.21", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "E1BI47", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BI47" } ] }, { "ec_number": "2.7.11.21", "activity": "", "evidence": [ { "id": "E1BI47", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BI47" } ] } ] }, { "uniprot_ac": "E1BJ19", "gene_name": "TAOK1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "E1BJ19", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BJ19" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "E1BJ19", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BJ19" } ] } ] }, { "uniprot_ac": "E1BJH5", "gene_name": "MAP4K3", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "E1BJH5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BJH5" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "E1BJH5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BJH5" } ] } ] }, { "uniprot_ac": "E1BJM5", "gene_name": "MTERF4", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "E1BJM5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BJM5" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "E1BJM5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BJM5" } ] } ] }, { "uniprot_ac": "E1BK33", "gene_name": "MAST1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "E1BK33", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BK33" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "E1BK33", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BK33" } ] } ] }, { "uniprot_ac": "E1BK52", "gene_name": "STK10", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "E1BK52", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BK52" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "E1BK52", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BK52" } ] } ] }, { "uniprot_ac": "E1BKX9", "gene_name": "CDKL5", "activity": [ { "ec_number": "2.7.11.22", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "E1BKX9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BKX9" } ] }, { "ec_number": "2.7.11.22", "activity": "", "evidence": [ { "id": "E1BKX9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BKX9" } ] } ] }, { "uniprot_ac": "E1BL08", "gene_name": "MAP3K14", "activity": [ { "ec_number": "2.7.11.25", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "E1BL08", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BL08" } ] }, { "ec_number": "2.7.11.25", "activity": "", "evidence": [ { "id": "E1BL08", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BL08" } ] } ] }, { "uniprot_ac": "E1BLQ5", "gene_name": "RPS6KB2", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "E1BLQ5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BLQ5" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "E1BLQ5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BLQ5" } ] } ] }, { "uniprot_ac": "E1BM19", "gene_name": "CDKL3", "activity": [ { "ec_number": "2.7.11.22", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "E1BM19", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BM19" } ] }, { "ec_number": "2.7.11.22", "activity": "", "evidence": [ { "id": "E1BM19", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BM19" } ] } ] }, { "uniprot_ac": "E1BMN8", "gene_name": "NLK", "activity": [ { "ec_number": "2.7.11.24", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "E1BMN8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BMN8" } ] }, { "ec_number": "2.7.11.24", "activity": "", "evidence": [ { "id": "E1BMN8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BMN8" } ] } ] }, { "uniprot_ac": "E1BN63", "gene_name": "WNK1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "E1BN63", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BN63" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "E1BN63", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BN63" } ] } ] }, { "uniprot_ac": "E1BN72", "gene_name": "NIM1K", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "E1BN72", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BN72" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "E1BN72", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BN72" } ] } ] }, { "uniprot_ac": "E1BNH0", "gene_name": "WNK2", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "E1BNH0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BNH0" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "E1BNH0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BNH0" } ] } ] }, { "uniprot_ac": "E1BNS8", "gene_name": "SIK1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "E1BNS8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BNS8" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "E1BNS8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BNS8" } ] } ] }, { "uniprot_ac": "E1BP01", "gene_name": "MYO3A", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "E1BP01", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BP01" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "E1BP01", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BP01" } ] } ] }, { "uniprot_ac": "E1BP72", "gene_name": "CDC42BPB", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "E1BP72", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BP72" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "E1BP72", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BP72" } ] } ] }, { "uniprot_ac": "E1BPB5", "gene_name": "TESK1", "activity": [ { "ec_number": "2.7.12.1", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "E1BPB5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BPB5" } ] }, { "ec_number": "2.7.12.1", "activity": "", "evidence": [ { "id": "E1BPB5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BPB5" } ] } ] }, { "uniprot_ac": "E1BPP1", "gene_name": "TTK", "activity": [ { "ec_number": "2.7.12.1", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "E1BPP1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BPP1" } ] }, { "ec_number": "2.7.12.1", "activity": "", "evidence": [ { "id": "E1BPP1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BPP1" } ] } ] }, { "uniprot_ac": "E1BPU0", "gene_name": "LRRK2", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "E1BPU0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BPU0" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "E1BPU0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BPU0" } ] } ] }, { "uniprot_ac": "E1BQ34", "gene_name": "HIPK1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "E1BQ34", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BQ34" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "E1BQ34", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BQ34" } ] } ] }, { "uniprot_ac": "F1MAZ8", "gene_name": "MARK3", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "F1MAZ8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MAZ8" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "F1MAZ8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MAZ8" } ] } ] }, { "uniprot_ac": "F1MBN7", "gene_name": "RIOK2", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "F1MBN7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MBN7" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "F1MBN7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MBN7" } ] } ] }, { "uniprot_ac": "F1MC27", "gene_name": "LMTK3", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "F1MC27", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MC27" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "F1MC27", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MC27" } ] } ] }, { "uniprot_ac": "F1MC61", "gene_name": "MAP3K11", "activity": [ { "ec_number": "2.7.11.25", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "F1MC61", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MC61" } ] }, { "ec_number": "2.7.11.25", "activity": "", "evidence": [ { "id": "F1MC61", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MC61" } ] } ] }, { "uniprot_ac": "F1MDC9", "gene_name": "PRKCE", "activity": [ { "ec_number": "2.7.11.13", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "F1MDC9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MDC9" } ] }, { "ec_number": "2.7.11.13", "activity": "", "evidence": [ { "id": "F1MDC9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MDC9" } ] } ] }, { "uniprot_ac": "F1MDS3", "gene_name": "PCK2", "activity": [ { "ec_number": "4.1.1.32", "activity": "ITP + oxaloacetate = IDP + phosphoenolpyruvate + CO2.", "evidence": [ { "id": "F1MDS3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MDS3" } ] }, { "ec_number": "4.1.1.32", "activity": "", "evidence": [ { "id": "F1MDS3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MDS3" } ] } ] }, { "uniprot_ac": "F1MF36", "gene_name": "KSR2", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "F1MF36", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MF36" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "F1MF36", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MF36" } ] } ] }, { "uniprot_ac": "F1MF50", "gene_name": "ROCK1", "activity": [ { "ec_number": "2.7.11.39", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "F1MF50", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MF50" } ] }, { "ec_number": "2.7.11.39", "activity": "", "evidence": [ { "id": "F1MF50", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MF50" } ] } ] }, { "uniprot_ac": "F1MFK1", "gene_name": "PKN2", "activity": [ { "ec_number": "2.7.11.13", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "F1MFK1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MFK1" } ] }, { "ec_number": "2.7.11.13", "activity": "", "evidence": [ { "id": "F1MFK1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MFK1" } ] } ] }, { "uniprot_ac": "F1MG29", "gene_name": "TSSK3", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "F1MG29", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MG29" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "F1MG29", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MG29" } ] } ] }, { "uniprot_ac": "F1MG35", "gene_name": "CIITA", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "F1MG35", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MG35" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "F1MG35", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MG35" } ] } ] }, { "uniprot_ac": "F1MG77", "gene_name": "HASPIN", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "F1MG77", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MG77" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "F1MG77", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MG77" } ] } ] }, { "uniprot_ac": "F1MGX2", "gene_name": "MAP3K13", "activity": [ { "ec_number": "2.7.11.25", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "F1MGX2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MGX2" } ] }, { "ec_number": "2.7.11.25", "activity": "", "evidence": [ { "id": "F1MGX2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MGX2" } ] } ] }, { "uniprot_ac": "F1MH23", "gene_name": "MAPKAPK5", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "F1MH23", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MH23" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "F1MH23", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MH23" } ] } ] }, { "uniprot_ac": "F1MH24", "gene_name": "AAK1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "F1MH24", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MH24" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "F1MH24", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MH24" } ] } ] }, { "uniprot_ac": "F1MH45", "gene_name": "CDC42BPA", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "F1MH45", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MH45" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "F1MH45", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MH45" } ] } ] }, { "uniprot_ac": "F1MI60", "gene_name": "MAP4K4", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "F1MI60", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MI60" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "F1MI60", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MI60" } ] } ] }, { "uniprot_ac": "F1MIB2", "gene_name": "GAK", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "F1MIB2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MIB2" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "F1MIB2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MIB2" } ] } ] }, { "uniprot_ac": "F1MJ55", "gene_name": "CSNK2A2", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "F1MJ55", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MJ55" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "F1MJ55", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MJ55" } ] } ] }, { "uniprot_ac": "F1MKK7", "gene_name": "PKMYT1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "F1MKK7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MKK7" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "F1MKK7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MKK7" } ] } ] }, { "uniprot_ac": "F1MKW8", "gene_name": "SIK2", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "F1MKW8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MKW8" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "F1MKW8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MKW8" } ] } ] }, { "uniprot_ac": "F1MKY9", "gene_name": "ALPK2", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "F1MKY9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MKY9" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "F1MKY9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MKY9" } ] } ] }, { "uniprot_ac": "F1MLY7", "gene_name": "ATR", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "F1MLY7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MLY7" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "F1MLY7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MLY7" } ] } ] }, { "uniprot_ac": "F1MM88", "gene_name": "NEK9", "activity": [ { "ec_number": "2.7.11.38", "activity": "L-threonyl-[protein] + ATP = O-phospho-L-threonyl-[protein] + ADP + H(+).", "evidence": [ { "id": "F1MM88", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MM88" } ] }, { "ec_number": "2.7.11.38", "activity": "", "evidence": [ { "id": "F1MM88", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MM88" } ] } ] }, { "uniprot_ac": "F1MN35", "gene_name": "PDIK1L", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "F1MN35", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MN35" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "F1MN35", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MN35" } ] } ] }, { "uniprot_ac": "F1MNP4", "gene_name": "RPS6KB1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "F1MNP4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MNP4" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "F1MNP4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MNP4" } ] } ] }, { "uniprot_ac": "F1MPF0", "gene_name": "TRPM7", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "F1MPF0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MPF0" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "F1MPF0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MPF0" } ] } ] }, { "uniprot_ac": "F1MPI8", "gene_name": "CDK8", "activity": [ { "ec_number": "2.7.11.22", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "F1MPI8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MPI8" } ] }, { "ec_number": "2.7.11.23", "activity": "[DNA-directed RNA polymerase] + ATP = phospho-[DNA-directed RNA polymerase] + ADP + H(+).", "evidence": [ { "id": "F1MPI8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MPI8" } ] }, { "ec_number": "2.7.11.22", "activity": "", "evidence": [ { "id": "F1MPI8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MPI8" } ] }, { "ec_number": "2.7.11.23", "activity": "", "evidence": [ { "id": "F1MPI8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MPI8" } ] } ] }, { "uniprot_ac": "F1MQ96", "gene_name": "PRKCI", "activity": [ { "ec_number": "2.7.11.13", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "F1MQ96", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MQ96" } ] }, { "ec_number": "2.7.11.13", "activity": "", "evidence": [ { "id": "F1MQ96", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MQ96" } ] } ] }, { "uniprot_ac": "F1MSI1", "gene_name": "STK17B", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "F1MSI1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MSI1" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "F1MSI1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MSI1" } ] } ] }, { "uniprot_ac": "F1MSV4", "gene_name": "SGK3", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "F1MSV4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MSV4" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "F1MSV4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MSV4" } ] } ] }, { "uniprot_ac": "F1MSX4", "gene_name": "MAP3K2", "activity": [ { "ec_number": "2.7.11.25", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "F1MSX4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MSX4" } ] }, { "ec_number": "2.7.11.25", "activity": "", "evidence": [ { "id": "F1MSX4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MSX4" } ] } ] }, { "uniprot_ac": "F1MU35", "gene_name": "PRKCG", "activity": [ { "ec_number": "2.7.11.13", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "F1MU35", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MU35" } ] }, { "ec_number": "2.7.11.13", "activity": "", "evidence": [ { "id": "F1MU35", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MU35" } ] } ] }, { "uniprot_ac": "F1MUU2", "gene_name": "STK35", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "F1MUU2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MUU2" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "F1MUU2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MUU2" } ] } ] }, { "uniprot_ac": "F1MVR0", "gene_name": "CDK19", "activity": [ { "ec_number": "2.7.11.22", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "F1MVR0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MVR0" } ] }, { "ec_number": "2.7.11.22", "activity": "", "evidence": [ { "id": "F1MVR0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MVR0" } ] } ] }, { "uniprot_ac": "F1MVV5", "gene_name": "MAPK4", "activity": [ { "ec_number": "2.7.11.24", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "F1MVV5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MVV5" } ] }, { "ec_number": "2.7.11.24", "activity": "", "evidence": [ { "id": "F1MVV5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MVV5" } ] } ] }, { "uniprot_ac": "F1MWN0", "gene_name": "EIF2AK1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "F1MWN0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MWN0" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "F1MWN0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MWN0" } ] } ] }, { "uniprot_ac": "F1MWP1", "gene_name": "BUB1B", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "F1MWP1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MWP1" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "F1MWP1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MWP1" } ] } ] }, { "uniprot_ac": "F1MXH6", "gene_name": "MAP3K5", "activity": [ { "ec_number": "2.7.11.25", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "F1MXH6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MXH6" } ] }, { "ec_number": "2.7.11.25", "activity": "", "evidence": [ { "id": "F1MXH6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MXH6" } ] } ] }, { "uniprot_ac": "F1MY55", "gene_name": "PAK5", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "F1MY55", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MY55" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "F1MY55", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MY55" } ] } ] }, { "uniprot_ac": "F1MY82", "gene_name": "PRKCH", "activity": [ { "ec_number": "2.7.11.13", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "F1MY82", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MY82" } ] }, { "ec_number": "2.7.11.13", "activity": "", "evidence": [ { "id": "F1MY82", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MY82" } ] } ] }, { "uniprot_ac": "F1MY86", "gene_name": "AURKC", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "F1MY86", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MY86" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "F1MY86", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MY86" } ] } ] }, { "uniprot_ac": "F1MYG2", "gene_name": "TLK1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "F1MYG2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MYG2" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "F1MYG2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MYG2" } ] } ] }, { "uniprot_ac": "F1MYM3", "gene_name": "PIK3CB", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "F1MYM3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MYM3" } ] }, { "ec_number": "2.7.1.153", "activity": "a 1,2-diacyl-sn-glycero-3-phospho-(1D-myo-inositol-4,5-bisphosphate) + ATP = a 1,2-diacyl-sn-glycero-3-phospho-(1D-myo-inositol-3,4,5-trisphosphate) + ADP + H(+).", "evidence": [ { "id": "F1MYM3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MYM3" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "F1MYM3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MYM3" } ] }, { "ec_number": "2.7.1.153", "activity": "", "evidence": [ { "id": "F1MYM3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MYM3" } ] } ] }, { "uniprot_ac": "F1MYV9", "gene_name": "OXSR1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "F1MYV9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MYV9" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "F1MYV9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MYV9" } ] } ] }, { "uniprot_ac": "F1N063", "gene_name": "CAMK1D", "activity": [ { "ec_number": "2.7.11.17", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "F1N063", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1N063" } ] }, { "ec_number": "2.7.11.17", "activity": "", "evidence": [ { "id": "F1N063", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1N063" } ] } ] }, { "uniprot_ac": "F1N2S7", "gene_name": "TSSK6", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "F1N2S7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1N2S7" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "F1N2S7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1N2S7" } ] } ] }, { "uniprot_ac": "F1N332", "gene_name": "ULK3", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "F1N332", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1N332" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "F1N332", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1N332" } ] } ] }, { "uniprot_ac": "F1N3W6", "gene_name": "MAP3K15", "activity": [ { "ec_number": "2.7.11.25", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "F1N3W6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1N3W6" } ] }, { "ec_number": "2.7.11.25", "activity": "", "evidence": [ { "id": "F1N3W6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1N3W6" } ] } ] }, { "uniprot_ac": "F1N5K1", "gene_name": "CDK11B", "activity": [ { "ec_number": "2.7.11.22", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "F1N5K1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1N5K1" } ] }, { "ec_number": "2.7.11.23", "activity": "[DNA-directed RNA polymerase] + ATP = phospho-[DNA-directed RNA polymerase] + ADP + H(+).", "evidence": [ { "id": "F1N5K1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1N5K1" } ] }, { "ec_number": "2.7.11.23", "activity": "", "evidence": [ { "id": "F1N5K1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1N5K1" } ] }, { "ec_number": "2.7.11.22", "activity": "", "evidence": [ { "id": "F1N5K1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1N5K1" } ] } ] }, { "uniprot_ac": "F1N5U0", "gene_name": "ALPK3", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "F1N5U0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1N5U0" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "F1N5U0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1N5U0" } ] } ] }, { "uniprot_ac": "F1N664", "gene_name": "MAP2K7", "activity": [ { "ec_number": "2.7.12.2", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "F1N664", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1N664" } ] }, { "ec_number": "2.7.12.2", "activity": "", "evidence": [ { "id": "F1N664", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1N664" } ] } ] }, { "uniprot_ac": "F1N6C1", "gene_name": "LRRK1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "F1N6C1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1N6C1" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "F1N6C1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1N6C1" } ] } ] }, { "uniprot_ac": "F6PN06", "gene_name": "TNK2", "activity": [ { "ec_number": "2.7.10.2", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "F6PN06", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F6PN06" } ] }, { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "F6PN06", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F6PN06" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "F6PN06", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F6PN06" } ] }, { "ec_number": "2.7.10.2", "activity": "", "evidence": [ { "id": "F6PN06", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F6PN06" } ] } ] }, { "uniprot_ac": "F6Q5B6", "gene_name": "EIF2AK2", "activity": [ { "ec_number": "2.7.10.2", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "F6Q5B6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F6Q5B6" } ] }, { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "F6Q5B6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F6Q5B6" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "F6Q5B6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F6Q5B6" } ] }, { "ec_number": "2.7.10.2", "activity": "", "evidence": [ { "id": "F6Q5B6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F6Q5B6" } ] } ] }, { "uniprot_ac": "F6Q5Z6", "gene_name": "BUB1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "F6Q5Z6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F6Q5Z6" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "F6Q5Z6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F6Q5Z6" } ] } ] }, { "uniprot_ac": "F6Q6K1", "gene_name": "CHEK1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "F6Q6K1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F6Q6K1" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "F6Q6K1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F6Q6K1" } ] } ] }, { "uniprot_ac": "F6Q9U9", "gene_name": "PNCK", "activity": [ { "ec_number": "2.7.11.17", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "F6Q9U9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F6Q9U9" } ] }, { "ec_number": "2.7.11.17", "activity": "", "evidence": [ { "id": "F6Q9U9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F6Q9U9" } ] } ] }, { "uniprot_ac": "F6QTX4", "gene_name": "RIPK3", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "F6QTX4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F6QTX4" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "F6QTX4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F6QTX4" } ] } ] }, { "uniprot_ac": "F6QVY2", "gene_name": "CDK20", "activity": [ { "ec_number": "2.7.11.22", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "F6QVY2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F6QVY2" } ] }, { "ec_number": "2.7.11.22", "activity": "", "evidence": [ { "id": "F6QVY2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F6QVY2" } ] } ] }, { "uniprot_ac": "F6QY93", "gene_name": "CDK3", "activity": [ { "ec_number": "2.7.11.22", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "F6QY93", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F6QY93" } ] }, { "ec_number": "2.7.11.22", "activity": "", "evidence": [ { "id": "F6QY93", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F6QY93" } ] } ] }, { "uniprot_ac": "F6RD87", "gene_name": "SRPK3", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "F6RD87", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F6RD87" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "F6RD87", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F6RD87" } ] } ] }, { "uniprot_ac": "F6RG88", "gene_name": "NEK4", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "F6RG88", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F6RG88" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "F6RG88", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F6RG88" } ] } ] }, { "uniprot_ac": "F6RLA2", "gene_name": "TSSK4", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "F6RLA2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F6RLA2" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "F6RLA2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F6RLA2" } ] } ] }, { "uniprot_ac": "F6RP02", "gene_name": "PIM2", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "F6RP02", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F6RP02" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "F6RP02", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F6RP02" } ] } ] }, { "uniprot_ac": "F6RPH3", "gene_name": "MAPK13", "activity": [ { "ec_number": "2.7.11.24", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "F6RPH3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F6RPH3" } ] }, { "ec_number": "2.7.11.24", "activity": "", "evidence": [ { "id": "F6RPH3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F6RPH3" } ] } ] }, { "uniprot_ac": "G3MX00", "gene_name": "", "activity": [ { "ec_number": "2.7.11.22", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "G3MX00", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3MX00" } ] }, { "ec_number": "2.7.11.22", "activity": "", "evidence": [ { "id": "G3MX00", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3MX00" } ] } ] }, { "uniprot_ac": "G3N022", "gene_name": "SPEG", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "G3N022", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3N022" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "G3N022", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3N022" } ] } ] }, { "uniprot_ac": "G3N2D2", "gene_name": "TSSK1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "G3N2D2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3N2D2" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "G3N2D2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3N2D2" } ] } ] }, { "uniprot_ac": "G3N2F6", "gene_name": "PIM3", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "G3N2F6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3N2F6" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "G3N2F6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3N2F6" } ] } ] }, { "uniprot_ac": "G3N2J4", "gene_name": "TTBK1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "G3N2J4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3N2J4" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "G3N2J4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3N2J4" } ] } ] }, { "uniprot_ac": "G5E518", "gene_name": "CDK12", "activity": [ { "ec_number": "2.7.11.22", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "G5E518", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G5E518" } ] }, { "ec_number": "2.7.11.23", "activity": "[DNA-directed RNA polymerase] + ATP = phospho-[DNA-directed RNA polymerase] + ADP + H(+).", "evidence": [ { "id": "G5E518", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G5E518" } ] }, { "ec_number": "2.7.11.22", "activity": "", "evidence": [ { "id": "G5E518", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G5E518" } ] }, { "ec_number": "2.7.11.23", "activity": "", "evidence": [ { "id": "G5E518", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G5E518" } ] } ] }, { "uniprot_ac": "G5E577", "gene_name": "MAPK6", "activity": [ { "ec_number": "2.7.11.24", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "G5E577", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G5E577" } ] }, { "ec_number": "2.7.11.24", "activity": "", "evidence": [ { "id": "G5E577", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G5E577" } ] } ] }, { "uniprot_ac": "G5E5A0", "gene_name": "STK17A", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "G5E5A0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G5E5A0" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "G5E5A0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G5E5A0" } ] } ] }, { "uniprot_ac": "G5E5D4", "gene_name": "MARK1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "G5E5D4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G5E5D4" } ] }, { "ec_number": "2.7.11.26", "activity": "L-seryl-[tau protein] + ATP = O-phospho-L-seryl-[tau protein] + ADP + H(+).", "evidence": [ { "id": "G5E5D4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G5E5D4" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "G5E5D4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G5E5D4" } ] }, { "ec_number": "2.7.11.26", "activity": "", "evidence": [ { "id": "G5E5D4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G5E5D4" } ] } ] }, { "uniprot_ac": "G5E5K2", "gene_name": "MASTL", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "G5E5K2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G5E5K2" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "G5E5K2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G5E5K2" } ] } ] }, { "uniprot_ac": "H2XJE8", "gene_name": "AAK1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "H2XJE8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/H2XJE8" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "H2XJE8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/H2XJE8" } ] } ] }, { "uniprot_ac": "H2XJE9", "gene_name": "NLK", "activity": [ { "ec_number": "2.7.11.24", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "H2XJE9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/H2XJE9" } ] }, { "ec_number": "2.7.11.24", "activity": "", "evidence": [ { "id": "H2XJE9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/H2XJE9" } ] } ] }, { "uniprot_ac": "P00516", "gene_name": "PRKG1", "activity": [ { "ec_number": "2.7.11.12", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "P00516", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P00516" } ] }, { "ec_number": "2.7.11.12", "activity": "", "evidence": [ { "id": "P00516", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P00516" } ] } ] }, { "uniprot_ac": "P00517", "gene_name": "PRKACA", "activity": [ { "ec_number": "2.7.11.11", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "P00517", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P00517" } ] }, { "ec_number": "2.7.11.11", "activity": "", "evidence": [ { "id": "P00517", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P00517" } ] } ] }, { "uniprot_ac": "P04409", "gene_name": "PRKCA", "activity": [ { "ec_number": "2.7.11.13", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "P04409", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P04409" } ] }, { "ec_number": "2.7.11.13", "activity": "", "evidence": [ { "id": "P04409", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P04409" } ] } ] }, { "uniprot_ac": "P05126", "gene_name": "PRKCB", "activity": [ { "ec_number": "2.7.11.13", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "P05126", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P05126" } ] }, { "ec_number": "2.7.11.13", "activity": "", "evidence": [ { "id": "P05126", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P05126" } ] } ] }, { "uniprot_ac": "P05128", "gene_name": "PRKCG", "activity": [ { "ec_number": "2.7.11.13", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "P05128", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P05128" } ] }, { "ec_number": "2.7.11.13", "activity": "", "evidence": [ { "id": "P05128", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P05128" } ] } ] }, { "uniprot_ac": "P05131", "gene_name": "PRKACB", "activity": [ { "ec_number": "2.7.11.11", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "P05131", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P05131" } ] }, { "ec_number": "2.7.11.11", "activity": "", "evidence": [ { "id": "P05131", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P05131" } ] } ] }, { "uniprot_ac": "P20427", "gene_name": "CSNK2A2", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "P20427", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P20427" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "P20427", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P20427" } ] } ] }, { "uniprot_ac": "P32871", "gene_name": "PIK3CA", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "P32871", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P32871" } ] }, { "ec_number": "2.7.1.153", "activity": "a 1,2-diacyl-sn-glycero-3-phospho-(1D-myo-inositol-4,5-bisphosphate) + ATP = a 1,2-diacyl-sn-glycero-3-phospho-(1D-myo-inositol-3,4,5-trisphosphate) + ADP + H(+).", "evidence": [ { "id": "P32871", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P32871" } ] }, { "ec_number": "2.7.1.137", "activity": "a 1,2-diacyl-sn-glycero-3-phospho-(1D-myo-inositol) + ATP = a 1,2-diacyl-sn-glycero-3-phospho-(1D-myo-inositol-3-phosphate) + ADP + H(+).", "evidence": [ { "id": "P32871", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P32871" } ] }, { "ec_number": "2.7.1.153", "activity": "", "evidence": [ { "id": "P32871", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P32871" } ] }, { "ec_number": "2.7.1.137", "activity": "", "evidence": [ { "id": "P32871", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P32871" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "P32871", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P32871" } ] } ] }, { "uniprot_ac": "P35507", "gene_name": "CSNK1B", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "P35507", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P35507" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "P35507", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P35507" } ] } ] }, { "uniprot_ac": "P35508", "gene_name": "CSNK1D", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "P35508", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P35508" } ] }, { "ec_number": "2.7.11.26", "activity": "L-seryl-[tau protein] + ATP = O-phospho-L-seryl-[tau protein] + ADP + H(+).", "evidence": [ { "id": "P35508", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P35508" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "P35508", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P35508" } ] } ] }, { "uniprot_ac": "P35509", "gene_name": "CSNK1G3", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "P35509", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P35509" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "P35509", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P35509" } ] } ] }, { "uniprot_ac": "P46196", "gene_name": "MAPK1", "activity": [ { "ec_number": "2.7.11.24", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "P46196", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P46196" } ] }, { "ec_number": "2.7.11.24", "activity": "", "evidence": [ { "id": "P46196", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P46196" } ] } ] }, { "uniprot_ac": "P48734", "gene_name": "CDK1", "activity": [ { "ec_number": "2.7.11.22", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "P48734", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P48734" } ] }, { "ec_number": "2.7.11.23", "activity": "[DNA-directed RNA polymerase] + ATP = phospho-[DNA-directed RNA polymerase] + ADP + H(+).", "evidence": [ { "id": "P48734", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P48734" } ] }, { "ec_number": "2.7.11.23", "activity": "", "evidence": [ { "id": "P48734", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P48734" } ] }, { "ec_number": "2.7.11.22", "activity": "", "evidence": [ { "id": "P48734", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P48734" } ] } ] }, { "uniprot_ac": "P52175", "gene_name": "NME1", "activity": [ { "ec_number": "3.1.11.-", "activity": "", "evidence": [ { "id": "P52175", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P52175" } ] }, { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "P52175", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P52175" } ] }, { "ec_number": "2.7.4.6", "activity": "UDP + ATP = UTP + ADP.", "evidence": [ { "id": "P52175", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P52175" } ] }, { "ec_number": "2.7.13.3", "activity": "ATP + protein L-histidine = ADP + protein N-phospho-L-histidine.", "evidence": [ { "id": "P52175", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P52175" } ] }, { "ec_number": "2.7.4.18", "activity": "(2E,6E)-farnesyl diphosphate + ATP = (2E,6E)-farnesyl triphosphate + ADP.", "evidence": [ { "id": "P52175", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P52175" } ] }, { "ec_number": "3.1.24.-", "activity": "", "evidence": [ { "id": "P52175", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P52175" } ] }, { "ec_number": "2.7.4.6", "activity": "", "evidence": [ { "id": "P52175", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P52175" } ] } ] }, { "uniprot_ac": "P67827", "gene_name": "CSNK1A1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "P67827", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P67827" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "P67827", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P67827" } ] } ] }, { "uniprot_ac": "P68399", "gene_name": "CSNK2A1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "P68399", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P68399" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "P68399", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P68399" } ] } ] }, { "uniprot_ac": "Q01314", "gene_name": "AKT1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "Q01314", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q01314" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "Q01314", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q01314" } ] } ] }, { "uniprot_ac": "Q02399", "gene_name": "CDK5", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "Q02399", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q02399" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "Q02399", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q02399" } ] } ] }, { "uniprot_ac": "Q08DZ2", "gene_name": "PRP4K", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "Q08DZ2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q08DZ2" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "Q08DZ2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q08DZ2" } ] } ] }, { "uniprot_ac": "Q08E52", "gene_name": "PAK1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "Q08E52", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q08E52" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "Q08E52", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q08E52" } ] } ] }, { "uniprot_ac": "Q0V7M1", "gene_name": "PSKH1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "Q0V7M1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q0V7M1" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "Q0V7M1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q0V7M1" } ] } ] }, { "uniprot_ac": "Q0VD22", "gene_name": "STK33", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "Q0VD22", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q0VD22" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "Q0VD22", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q0VD22" } ] } ] }, { "uniprot_ac": "Q17QV9", "gene_name": "STK40", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "Q17QV9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q17QV9" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "Q17QV9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q17QV9" } ] } ] }, { "uniprot_ac": "Q17R13", "gene_name": "TNK2", "activity": [ { "ec_number": "2.7.10.2", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "Q17R13", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q17R13" } ] }, { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "Q17R13", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q17R13" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "Q17R13", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q17R13" } ] }, { "ec_number": "2.7.10.2", "activity": "", "evidence": [ { "id": "Q17R13", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q17R13" } ] } ] }, { "uniprot_ac": "Q1RMT7", "gene_name": "RIOK3", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "Q1RMT7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q1RMT7" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "Q1RMT7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q1RMT7" } ] } ] }, { "uniprot_ac": "Q1RMT8", "gene_name": "IRAK4", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "Q1RMT8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q1RMT8" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "Q1RMT8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q1RMT8" } ] } ] }, { "uniprot_ac": "Q28021", "gene_name": "ROCK2", "activity": [ { "ec_number": "2.7.11.39", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "Q28021", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q28021" } ] }, { "ec_number": "2.7.11.39", "activity": "", "evidence": [ { "id": "Q28021", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q28021" } ] } ] }, { "uniprot_ac": "Q2HJF7", "gene_name": "CAMK2D", "activity": [ { "ec_number": "2.7.11.17", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "Q2HJF7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q2HJF7" } ] }, { "ec_number": "2.7.11.17", "activity": "", "evidence": [ { "id": "Q2HJF7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q2HJF7" } ] } ] }, { "uniprot_ac": "Q2KIP2", "gene_name": "HASPIN", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "Q2KIP2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q2KIP2" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "Q2KIP2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q2KIP2" } ] } ] }, { "uniprot_ac": "Q2KJG8", "gene_name": "BCKDK", "activity": [ { "ec_number": "2.7.11.-", "activity": "", "evidence": [ { "id": "Q2KJG8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q2KJG8" } ] }, { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "Q2KJG8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q2KJG8" } ] }, { "ec_number": "2.7.11.4", "activity": "L-seryl-[3-methyl-2-oxobutanoate dehydrogenase] + ATP = O-phospho-L-seryl-[3-methyl-2-oxobutanoate dehydrogenase] + ADP + H(+).", "evidence": [ { "id": "Q2KJG8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q2KJG8" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "Q2KJG8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q2KJG8" } ] } ] }, { "uniprot_ac": "Q2LGB3", "gene_name": "IRAK1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "Q2LGB3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q2LGB3" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "Q2LGB3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q2LGB3" } ] } ] }, { "uniprot_ac": "Q2TA06", "gene_name": "AURKA", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "Q2TA06", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q2TA06" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "Q2TA06", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q2TA06" } ] } ] }, { "uniprot_ac": "Q2TA25", "gene_name": "PLK1", "activity": [ { "ec_number": "2.7.11.21", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "Q2TA25", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q2TA25" } ] }, { "ec_number": "2.7.11.21", "activity": "", "evidence": [ { "id": "Q2TA25", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q2TA25" } ] } ] }, { "uniprot_ac": "Q2TBL8", "gene_name": "CDK10", "activity": [ { "ec_number": "2.7.11.22", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "Q2TBL8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q2TBL8" } ] }, { "ec_number": "2.7.11.22", "activity": "", "evidence": [ { "id": "Q2TBL8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q2TBL8" } ] } ] }, { "uniprot_ac": "Q2YDN8", "gene_name": "VRK3", "activity": [ { "ec_number": "2.7.11.22", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "Q2YDN8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q2YDN8" } ] }, { "ec_number": "2.7.11.22", "activity": "", "evidence": [ { "id": "Q2YDN8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q2YDN8" } ] } ] }, { "uniprot_ac": "Q32KY4", "gene_name": "CDK4", "activity": [ { "ec_number": "2.7.11.22", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "Q32KY4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q32KY4" } ] }, { "ec_number": "2.7.11.22", "activity": "", "evidence": [ { "id": "Q32KY4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q32KY4" } ] } ] }, { "uniprot_ac": "Q32L23", "gene_name": "LIMK2", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "Q32L23", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q32L23" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "Q32L23", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q32L23" } ] } ] }, { "uniprot_ac": "Q32PI1", "gene_name": "VRK1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "Q32PI1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q32PI1" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "Q32PI1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q32PI1" } ] } ] }, { "uniprot_ac": "Q3MHJ9", "gene_name": "CAMK2B", "activity": [ { "ec_number": "2.7.11.17", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "Q3MHJ9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q3MHJ9" } ] }, { "ec_number": "2.7.11.17", "activity": "", "evidence": [ { "id": "Q3MHJ9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q3MHJ9" } ] } ] }, { "uniprot_ac": "Q3SWY6", "gene_name": "STK25", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "Q3SWY6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q3SWY6" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "Q3SWY6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q3SWY6" } ] } ] }, { "uniprot_ac": "Q3SX21", "gene_name": "CLK3", "activity": [ { "ec_number": "2.7.12.1", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "Q3SX21", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q3SX21" } ] }, { "ec_number": "2.7.12.1", "activity": "", "evidence": [ { "id": "Q3SX21", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q3SX21" } ] } ] }, { "uniprot_ac": "Q3SYZ2", "gene_name": "MAPKAPK3", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "Q3SYZ2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q3SYZ2" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "Q3SYZ2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q3SYZ2" } ] } ] }, { "uniprot_ac": "Q3SZJ2", "gene_name": "RIPK2", "activity": [ { "ec_number": "2.7.10.2", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "Q3SZJ2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q3SZJ2" } ] }, { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "Q3SZJ2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q3SZJ2" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "Q3SZJ2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q3SZJ2" } ] } ] }, { "uniprot_ac": "Q3SZW1", "gene_name": "TSSK1B", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "Q3SZW1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q3SZW1" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "Q3SZW1", 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"UniProtKB", "id": "F6QED7", "url": "https://www.uniprot.org/uniprotkb/F6QED7" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "homologset.oma", "label": "OMA Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": 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"ENSBTAG00000017765", "url": "https://bgee.org/?page=gene&gene_id=ENSBTAG00000017765", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "cd03075", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd03075", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "cd03209", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd03209", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "783879", "url": "https://www.ncbi.nlm.nih.gov/gene/783879", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR003081", "url": "https://www.ebi.ac.uk/interpro/entry/IPR003081", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR004045", "url": "https://www.ebi.ac.uk/interpro/entry/IPR004045", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR004046", "url": "https://www.ebi.ac.uk/interpro/entry/IPR004046", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR010987", "url": "https://www.ebi.ac.uk/interpro/entry/IPR010987", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR036249", "url": "https://www.ebi.ac.uk/interpro/entry/IPR036249", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR036282", "url": "https://www.ebi.ac.uk/interpro/entry/IPR036282", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR040079", "url": "https://www.ebi.ac.uk/interpro/entry/IPR040079", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR050213", "url": "https://www.ebi.ac.uk/interpro/entry/IPR050213", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "A0A3Q1LY34", "url": "https://www.orthodb.org/?gene=A0A3Q1LY34", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR11571", "url": 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[ "Protein" ] }, { "id": "A0A3Q1LY34-1", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1LY34-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "F6QEM8", "url": "https://www.uniprot.org/uniprotkb/F6QEM8", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "F6QEM8-1", "url": "https://www.uniprot.org/uniprotkb/F6QEM8-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MAMTLGYWDIRGVSGGPLGRVGWPLQPSPFASPPPSQLAHAIRLLLEYTDSNYEEKKYTMGDAPDYDRSQWLNEKFKLGLDFPNLPYLIDGAHRLTQSKAILRYIARKHNMCGETEEEKIRVDVLENQTMDTANELAILCYNPEFEKLKSQYLKEIPGKMKLYSEFLGRRPWFAGDKLTFVDFLVYDVLDIHRIFEPKCLDAFPNLKDFISHFEGLKRISAYMKSSRFLPHPVYSKMAVWGNK", "length": 243, "header": "tr|F6QEM8-1|F6QEM8_BOVIN Isoform 1 of Glutathione S-transferase OS=Bos taurus OX=9913 GN=LOC783879 PE=3 SV=1 CANONICAL=F6QEM8-1" }, "isoforms": [ { "isoform_ac": "A0A3Q1LY34-1", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1LY34/entry", "sequence": { "sequence": 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"MAMTLGYWDIRGVSGGPLGRVGWPLQPSPFASPPPSQLAHAIRLLLEYTDSNYEEKKYTMGDAPDYDRSQWLNEKFKLGLDFPNLPYLIDGAHRLTQSKAILRYIARKHNMCGETEEEKIRVDVLENQTMDTANELAILCYNPEFEKLKSQYLKEIPGKMKLYSEFLGRRPWFAGDKLTFVDFLVYDVLDIHRIFEPKCLDAFPNLKDFISHFEGLKRISAYMKSSRFLPHPVYSKMAVWGNK", "length": 243, "header": "tr|F6QEM8-1|F6QEM8_BOVIN Isoform 1 of Glutathione S-transferase OS=Bos taurus OX=9913 GN=LOC783879 PE=3 SV=1 CANONICAL=F6QEM8-1" }, "locus": { "chromosome": "3", "start_pos": 33765786, "end_pos": 33759681, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000021896.7", "url": "https://www.ensembl.org/id/ENSBTAT00000021896.7" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000021896.6", "url": "https://www.ensembl.org/id/ENSBTAP00000021896.6" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [ "enzyme" ], "publication": [], "pathway": [], "orthologs": [], "go_annotation": { "categories": [ { "name": "Molecular Function", "total": 1, "go_terms": [ { 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"A0ABI0P5M0-1", "A0AAA9TW47-1", "F6QEM8-1", "A0ABI0P3R2-1", "A0AAF6Z0W3-1", "P28801-1", "Q2KJG4-1", "A0A3Q1LMV5-1", "F1MVX2-1", "Q28035-1", "Q9N0V4-1", "Q2NL00-1", "F1MXY2-1", "E1BED9-1", "A0ABI0P006-1", "Q5E9G0-1", "Q64L89-1", "A0A452DIU1-1", "F1MGZ9-1", "A0AAA9TXU3-1", "E1BJX2-1" ], "evidence": [ { "id": "16437", "database": "Rhea", "url": "https://www.rhea-db.org/rhea/16437" } ] } ], "reaction_participants": [], "reaction_enzymes": [ { "uniprot_ac": "A0A3Q1LMV5", "gene_name": "LOC281806", "activity": [ { "ec_number": "2.5.1.18", "activity": "RX + glutathione = an S-substituted glutathione + a halide anion + H(+).", "evidence": [ { "id": "A0A3Q1LMV5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1LMV5" } ] }, { "ec_number": "2.5.1.18", "activity": "", "evidence": [ { "id": "A0A3Q1LMV5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1LMV5" } ] } ] }, { "uniprot_ac": "A0A452DIU1", "gene_name": "LOC327709", "activity": [ { 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Involved in the control of feeding behavior via the central melanocortin system. Has very low activity towards MC5R. Also promotes endocytosis of MC3R and MC4R in an arrestin-dependent mechanism.", "evidence": [ { "database": "UniProtKB", "id": "F6QHL3", "url": "https://www.uniprot.org/uniprotkb/F6QHL3#function" }, { "database": "UniProtKB", "id": "ARBA00094299", "url": "https://www.uniprot.org/uniprotkb/ARBA00094299#function" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Bos taurus", "taxid": 9913, "evidence": [ { "database": "UniProtKB", "id": "F6QHL3", "url": "https://www.uniprot.org/uniprotkb/F6QHL3" } ], "common_name": "Bovine", "glygen_name": "Bovine", "reference_species": "Bos taurus [9913]" } ], "gene": [ { "name": "AGRP", "url": "https://www.uniprot.org/uniprotkb/F6QHL3", "locus": { "chromosome": "18", "start_pos": 35085839, "end_pos": 35087550, "strand": "+", "evidence": [ { "database": "Ensembl Gene", "id": "ENSBTAG00000014556", "url": "https://www.ensembl.org/id/ENSBTAG00000014556" } ] } } ], "crossref": [ { "id": "F6QHL3", "url": "https://alphafold.ebi.ac.uk/entry/F6QHL3", "database": "AlphaFoldDB", "categories": [] }, { "id": "IPR007733", "url": "https://www.ebi.ac.uk/interpro/entry/IPR007733", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR027300", "url": "https://www.ebi.ac.uk/interpro/entry/IPR027300", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR036836", "url": "https://www.ebi.ac.uk/interpro/entry/IPR036836", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "PTHR16551", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR16551", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR16551:SF4", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR16551:SF4", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF05039", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF05039", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "F6QHL3", "url": "https://www.uniprot.org/uniprotkb/F6QHL3", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "F6QHL3-1", "url": "https://www.uniprot.org/uniprotkb/F6QHL3-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MEWSATPGARIQQAEAMLTAVLLSCALLLAMPPMQGAQMGPAPLEGIGRPEEALFLELQGLSLQPSLKRITEEQAEESLLQEAEAKALAEVLDPEGRKPRSPRRCVRLHESCLGHQVPCCDPCATCYCRFFNAFCYCRKLGTTTNPCSRT", "length": 150, "header": "tr|F6QHL3-1|F6QHL3_BOVIN Isoform 1 of Agouti-related protein OS=Bos taurus OX=9913 GN=AGRP PE=4 SV=1 CANONICAL=F6QHL3-1" }, "isoforms": [ { "isoform_ac": "F6QHL3-1", "url": "https://www.uniprot.org/uniprotkb/F6QHL3/entry", "sequence": { "sequence": "MEWSATPGARIQQAEAMLTAVLLSCALLLAMPPMQGAQMGPAPLEGIGRPEEALFLELQGLSLQPSLKRITEEQAEESLLQEAEAKALAEVLDPEGRKPRSPRRCVRLHESCLGHQVPCCDPCATCYCRFFNAFCYCRKLGTTTNPCSRT", "length": 150, "header": "tr|F6QHL3-1|F6QHL3_BOVIN Isoform 1 of Agouti-related protein OS=Bos taurus OX=9913 GN=AGRP PE=4 SV=1 CANONICAL=F6QHL3-1" }, "locus": { "chromosome": "18", "start_pos": 35087351, "end_pos": 35086442, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000019347.4", "url": "https://www.ensembl.org/id/ENSBTAT00000019347.4" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000019347.3", "url": "https://www.ensembl.org/id/ENSBTAP00000019347.3" } ] } } ], "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "other", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 6, "start_aa": "Thr", "end_pos": 6, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr6", "evidence": [ { "id": "", "database": "GlyGen", "url": "https://data.glygen.org/" } ], "filter_code": "000000000000000010000.00000000001000.0.01000" } ], "phosphorylation": [], "glycation": [], "keywords": [ "glycoprotein", "glycoprotein_predicted" ], "publication": [], "pathway": [], "orthologs": [], "go_annotation": { "categories": [ { "name": "Biological Process", "total": 5, "go_terms": [ { "name": "positive regulation of appetite", "id": "GO:0032100", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0032100", "evidence": [ { "database": "UniProtKB", "id": "F6QHL3", "url": "https://www.uniprot.org/uniprotkb/F6QHL3" } ], "pmid": "" }, { "name": "neuropeptide signaling pathway", "id": "GO:0007218", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007218", "evidence": [ { "database": "UniProtKB", "id": "F6QHL3", "url": "https://www.uniprot.org/uniprotkb/F6QHL3" } ], "pmid": "" }, { "name": "hormone-mediated signaling pathway", "id": "GO:0009755", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0009755", "evidence": [ { "database": "UniProtKB", "id": "F6QHL3", "url": "https://www.uniprot.org/uniprotkb/F6QHL3" } ], "pmid": "" }, { "name": "regulation of feeding behavior", "id": "GO:0060259", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0060259", "evidence": [ { "database": "UniProtKB", "id": "F6QHL3", "url": "https://www.uniprot.org/uniprotkb/F6QHL3" } ], "pmid": "" }, { "name": "negative regulation of adenylate cyclase-activating G protein-coupled receptor signaling pathway", "id": "GO:0106072", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0106072", "evidence": [ { "database": "UniProtKB", "id": "F6QHL3", "url": "https://www.uniprot.org/uniprotkb/F6QHL3" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 2, "go_terms": [ { "name": "extracellular space", "id": "GO:0005615", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005615", "evidence": [ { "database": "UniProtKB", "id": "F6QHL3", "url": "https://www.uniprot.org/uniprotkb/F6QHL3" } ], "pmid": "" }, { "name": "Golgi lumen", "id": "GO:0005796", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005796", "evidence": [ { "database": "UniProtKB", "id": "F6QHL3", "url": "https://www.uniprot.org/uniprotkb/F6QHL3" } ], "pmid": "" } ] }, { "name": "Molecular Function", "total": 2, "go_terms": [ { "name": "receptor antagonist activity", "id": "GO:0048019", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0048019", "evidence": [ { "database": "UniProtKB", "id": "F6QHL3", "url": "https://www.uniprot.org/uniprotkb/F6QHL3" } ], "pmid": "" }, { "name": "neuropeptide hormone activity", "id": "GO:0005184", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005184", "evidence": [ { "database": "UniProtKB", "id": "F6QHL3", "url": "https://www.uniprot.org/uniprotkb/F6QHL3" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "F6QHL3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F6QHL3" }, { "id": "PS51150", "database": "PROSITE", "url": "https://prosite.expasy.org/PS51150" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "Agouti", "eco_id": "ECO_0000259", "start_pos": 105, "end_pos": 147, "start_aa": "Cys", "end_aa": "Cys", "glycosite_overlap": [] } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [ 6 ], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 1 }, { "field": "total_sites", "count": 1 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 1 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": 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"field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 1 }, { "field": "total_sites", "count": 1 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 1 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "exact_sites", "count": 1 }, { "field": "exact_o_linked_sites", "count": 1 }, { "field": "fuzzy_sites", "count": 0 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_pos", "start_aa", "end_pos", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ], "tool_support": { "graph_view": "yes" } }, { "uniprot_canonical_ac": "F6QI44-1", "uniprot_ac": "F6QI44", "uniprot_id": "F6QI44_BOVIN", "mass": { "chemical_mass": 22976.0, "monoisotopic_mass": 22976.0 }, "refseq": { "ac": "XP_059734515", "name": "keratin-associated protein 4-7-like", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_059734515" }, "gene_names": [ { "name": "LOC132343072", "type": "recommended", "evidence": [ { "id": "F6QI44", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F6QI44" } ] }, { "name": "LOC132343072", "type": "synonym", "evidence": [ { "id": "XP_059734515", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_059734515" } ] } ], "protein_names": [ { "name": "Uncharacterized protein", "type": "synonym", "evidence": [ { "id": "F6QI44", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F6QI44/entry#names_and_taxonomy" } ] }, { "name": "keratin-associated protein 4-7-like", "type": "synonym", "evidence": [ { "id": "XP_059734515", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_059734515" } ] } ], "function": [ { "annotation": "In the hair cortex, hair keratin intermediate filaments are embedded in an interfilamentous matrix, consisting of hair keratin-associated proteins (KRTAP), which are essential for the formation of a rigid and resistant hair shaft through their extensive disulfide bond cross-linking with abundant cysteine residues of hair keratins. The matrix proteins include the high-sulfur and high-glycine-tyrosine keratins.", "evidence": [ { "database": "UniProtKB", "id": "F6QI44", "url": "https://www.uniprot.org/uniprotkb/F6QI44#function" }, { "database": "UniProtKB", "id": "ARBA00003327", "url": "https://www.uniprot.org/uniprotkb/ARBA00003327#function" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Bos taurus", "taxid": 9913, "evidence": [ { "database": "UniProtKB", "id": "F6QI44", "url": "https://www.uniprot.org/uniprotkb/F6QI44" } ], "common_name": "Bovine", "glygen_name": "Bovine", "reference_species": "Bos taurus [9913]" } ], "gene": [ { "name": "LOC132343072", "url": "https://www.uniprot.org/uniprotkb/F6QI44", "locus": {} } ], "crossref": [ { "id": "F6QI44", "url": "https://alphafold.ebi.ac.uk/entry/F6QI44", "database": "AlphaFoldDB", "categories": [] }, { "id": "132343072", "url": "https://www.ncbi.nlm.nih.gov/gene/132343072", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR002494", "url": "https://www.ebi.ac.uk/interpro/entry/IPR002494", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "bta:132343072", "url": "https://www.genome.jp/dbget-bin/www_bget?bta:132343072", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "CCVRGSC", "url": "https://omabrowser.org/oma/group/CCVRGSC/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "PTHR23262", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR23262", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR23262:SF183", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR23262:SF183", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF13885", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF13885", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "XP_059734515", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_059734515", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "F6QI44", "url": "https://www.uniprot.org/uniprotkb/F6QI44", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "F6QI44-1", "url": "https://www.uniprot.org/uniprotkb/F6QI44-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MVSSCCGSVCSDQSCGRSLCQETCCQPSCCQTTCCRTTCCRPSCGVSSCCRPVCCQPTCPRPTCCISSCYRPSCCVSSCGSSCCRPTCCISSCCRPQCCQPVCCQPTCPRPTCCISSCCRPSCCGSSCGSSCCRPTCCISSCCRPTCCISSCCRPRCCQSVCCQPTCSRISSCCRPSCCGSSCCLRPVCGRVSCHTTCYRPTCVISTCPRPVCCPSSCC", "length": 219, "header": "tr|F6QI44-1|F6QI44_BOVIN Isoform 1 of Uncharacterized protein OS=Bos taurus OX=9913 GN=LOC132343072 PE=4 SV=1 CANONICAL=F6QI44-1" }, "isoforms": [ { "isoform_ac": "F6QI44-1", "url": "https://www.uniprot.org/uniprotkb/F6QI44/entry", "sequence": { "sequence": "MVSSCCGSVCSDQSCGRSLCQETCCQPSCCQTTCCRTTCCRPSCGVSSCCRPVCCQPTCPRPTCCISSCYRPSCCVSSCGSSCCRPTCCISSCCRPQCCQPVCCQPTCPRPTCCISSCCRPSCCGSSCGSSCCRPTCCISSCCRPTCCISSCCRPRCCQSVCCQPTCSRISSCCRPSCCGSSCCLRPVCGRVSCHTTCYRPTCVISTCPRPVCCPSSCC", "length": 219, "header": "tr|F6QI44-1|F6QI44_BOVIN Isoform 1 of Uncharacterized protein OS=Bos taurus OX=9913 GN=LOC132343072 PE=4 SV=1 CANONICAL=F6QI44-1" }, "locus": { "chromosome": "19", "start_pos": 41338077, "end_pos": 41337421, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000043148.5", "url": "https://www.ensembl.org/id/ENSBTAT00000043148.5" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000040738.3", "url": "https://www.ensembl.org/id/ENSBTAP00000040738.3" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [ { "id": "bta:132343072", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?bta:132343072", "resource": "KEGG Pathway" } ], "orthologs": [ { "uniprot_canonical_ac": "Q9BYQ6-1", "protein_name": "Keratin-associated protein 4-11", "gene_name": "KRTAP4-11", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MVNSCCGSVCSHQGCGRDLCQETCCRPSCCETTCCRTTYCRPSCCVSSCCRPQCCQSVCCQPTCCRPRCCISSCCRPSCCVSSCCKPQCCQSMCCQPTCCRPRCCISSCCRPSCCVSSCCRPQCCQSVCCQPTCCHPSCSISSCCRPSCCESSCCRPCCCLRPVCGRVSCHTTCYRPTCVISSCPRPLCCASSCC", "length": 195 }, "evidence": [ { "id": "F6QI44", "url": "https://omabrowser.org/oma/group/F6QI44/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" } ], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 2, "go_terms": [ { "name": "cytosol", "id": "GO:0005829", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005829", "evidence": [ { "database": "UniProtKB", "id": "F6QI44", "url": "https://www.uniprot.org/uniprotkb/F6QI44" } ], "pmid": "" }, { "name": "keratin filament", "id": "GO:0045095", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0045095", "evidence": [ { 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"header": "tr|F6QJQ2-1|F6QJQ2_BOVIN Isoform 1 of Proline rich transmembrane protein 3 OS=Bos taurus OX=9913 GN=PRRT3 PE=4 SV=3 CANONICAL=F6QJQ2-1" }, "isoforms": [ { "isoform_ac": "F6QJQ2-1", "url": "https://www.uniprot.org/uniprotkb/F6QJQ2/entry", "sequence": { "sequence": "MAPSPWGCVHGLLLLLPLLSLGASPALGRGLPRPLEDSEPHLAPGAQGKGPLDTERQAFDFFWENPRDESPWNASVPQVPAEEMPERPEDALGPALHGPKAAHGAQKGGLPVTDDLQMARGPISQGWTGPPDSQEPMEQEAPVPYPVGAPHLPFFPTTPRLHLGLATVPPTSGGPGGRVGQLPPRDEGLLAKGKTRVSETFPEDHKGPSPTLVPHPGIVARPGMEEQGGGEEDFQEAVQGPLSTQQGPAAPDTGSVSPAEGASSQEPESQPDLALARSLPPAEEQPMELPKTAGAGEAWEVSSSSPSPKEAHLPDVRGSPGPQPSDLPSSETSDGQPKPELAAMNGADPISPQRVRGAVEAPGTPKSLIPGPLDLGPTANRTESPVGSLKPDEAEEWPGRPQSHPPAPPVQAPSTSRRGLIRVTTQRALGQPPPPEPSASSMASVPASSPPTNATAPPLRWGPLRRVLSFSWELHVYGVGVLFLLPALLALASLAAAPAGPRLALVAAVLVLVAGGLRSAYMLTDPYGSQARLGLRAGLVLYNLPFPLLLTALAALTLLGLGAGLPQQLQNPLLLGALALTHGLGLLTTDLLSVRPALNLLAQGLSCAWGAAVALGTLCLCRRRLLDGPRGWDASPGPRLLAVAGALGLLASGLQLAAALWLYPGPGRVGRFSWAWWGVHFWLRLLELTWALTLALAALAAARPRPPTEHACWAKLLRLACPTPSSKSEVPERPNNCYAGPSGVSAGTLDISKSLIRNPAEGGPPATPSSGAWGSATSLSRGPQGGPGLSRSSVGPAPSISELDLRPPSPINLSRSIDAALFREHLVQDSVFRRCGLRCLASPPPGGALRSRRGSHPDAELDGLGSSLLRGRCRSLSDVRVRGPVPPHVVEEADAAASGSSVDSFSRGSLKISWNPWRHGLSSVDSLPLDELPSTVQLLSTPAPAPAPAWSGEPQNGVQPRCKTGDSRSASSDTIEL", "length": 977, "header": "tr|F6QJQ2-1|F6QJQ2_BOVIN Isoform 1 of Proline rich transmembrane protein 3 OS=Bos taurus OX=9913 GN=PRRT3 PE=4 SV=3 CANONICAL=F6QJQ2-1" }, "locus": { "chromosome": "22", "start_pos": 16819412, "end_pos": 16815679, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000014379.8", "url": "https://www.ensembl.org/id/ENSBTAT00000014379.8" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000014379.7", "url": "https://www.ensembl.org/id/ENSBTAP00000014379.7" } ] } } ], "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "other", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 171, "start_aa": "Thr", "end_pos": 171, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr171", "evidence": [ { "id": "", "database": "GlyGen", 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"start_aa": "Thr", "end_pos": 767, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr767", "evidence": [ { "id": "", "database": "GlyGen", "url": "https://data.glygen.org/" } ], "filter_code": "000000000000000010000.00000000001000.0.01000" } ], "phosphorylation": [], "glycation": [], "keywords": [ "glycoprotein", "glycoprotein_predicted" ], "publication": [], "pathway": [], "orthologs": [], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 1, "go_terms": [ { "name": "membrane", "id": "GO:0016020", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016020", "evidence": [ { "database": "UniProtKB", "id": "F6QJQ2", "url": "https://www.uniprot.org/uniprotkb/F6QJQ2" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 380, "end_pos": 382, "annotation": "n_glycosylation_sequon" }, { "start_pos": 453, "end_pos": 455, "annotation": "n_glycosylation_sequon" }, { "start_pos": 73, "end_pos": 75, "annotation": "n_glycosylation_sequon" }, { 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"glycosite_overlap": [] } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [ 171, 723, 767 ], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 380, "end_pos": 382 }, { "start_pos": 453, "end_pos": 455 }, { "start_pos": 73, "end_pos": 75 }, { "start_pos": 812, "end_pos": 814 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 3 }, { "field": "total_sites", "count": 3 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 3 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "exact_sites", "count": 3 }, { "field": "exact_o_linked_sites", "count": 3 }, { "field": 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"sort_fields": [] } ], "tool_support": { "graph_view": "yes" } }, { "uniprot_canonical_ac": "F6QKQ1-1", "uniprot_ac": "F6QKQ1", "uniprot_id": "F6QKQ1_BOVIN", "mass": { "chemical_mass": 70058.0, "monoisotopic_mass": 70058.0 }, "refseq": { "ac": "XP_005228173", "name": "prickle planar cell polarity protein 3 isoform X1", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_005228173" }, "gene_names": [ { "name": "PRICKLE3", "type": "recommended", "evidence": [ { "id": "F6QKQ1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F6QKQ1" } ] }, { "name": "LMO6", "type": "synonym", "evidence": [ { "id": "XP_005228173", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_005228173" } ] }, { "name": "PRICKLE3", "type": "synonym", "evidence": [ { "id": "XP_005228173", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_005228173" } ] } ], "protein_names": [ { "name": "Prickle planar cell polarity protein 3", "type": "synonym", 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"https://www.ncbi.nlm.nih.gov/protein/XP_005228173", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "F6QKQ1", "url": "https://www.uniprot.org/uniprotkb/F6QKQ1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "F6QKQ1-1", "url": "https://www.uniprot.org/uniprotkb/F6QKQ1-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MFARGSRRRRSGRAPPEAEDPDRGQPCNSCREQCPGFLLHGWRKICQHCKCPREEHAVHAVPVDLERIMCRLISDFQRHSISDDDSGCASEEYAWVPPGLKPEQVYQFFSCLPEDKVPYVNSPGEKYRIKQLLHQLPPHDSEVQYCTALEEEEKKELRAFSQQRKRENLGRGTVRIFPVTITGAICEECSPVIPQCGKQIGGGDIAVFASRAGLGACWHPQCFVCSTCRELLVDLIYFYHAGKVYCGRHHAERLRPRCQACDEIIFSPECTEAEGRHWHMDHFCCFECEASLGGQRYVMRQSRPHCCACYEARHAEYCDGCGEHIGLDQGQMAYEGQHWHASERCFCCSRCGRALLGRPFLPRRGLIFCSRACSLGSEPMAPAHSRRSWSTSTVSTPLTASTASFSAVEGASETTTKGTNTEAAPAADPEEPTHFLRGAPHRHSMPELGLRSVPEPPLGPPSQPDPRPEDGAFGRQSAPRVSFRDPLVSEGGPRRTLSAPPAQRRRPRSPPPRGPMRRRRHRHHHDHHHHHHHHRCHFGRRRHHQCDLGSGSDSGSCSSSPSSSSSESSEEDGYFLGERIPLSPHLCRPVLAQDTAAETTNSPSPQLPGNSRPGISRQARDKNCIVA", "length": 627, "header": "tr|F6QKQ1-1|F6QKQ1_BOVIN Isoform 1 of Prickle planar cell polarity protein 3 OS=Bos taurus OX=9913 GN=PRICKLE3 PE=3 SV=2 CANONICAL=F6QKQ1-1" }, "isoforms": [ { "isoform_ac": "F6QKQ1-1", "url": "https://www.uniprot.org/uniprotkb/F6QKQ1/entry", "sequence": { "sequence": "MFARGSRRRRSGRAPPEAEDPDRGQPCNSCREQCPGFLLHGWRKICQHCKCPREEHAVHAVPVDLERIMCRLISDFQRHSISDDDSGCASEEYAWVPPGLKPEQVYQFFSCLPEDKVPYVNSPGEKYRIKQLLHQLPPHDSEVQYCTALEEEEKKELRAFSQQRKRENLGRGTVRIFPVTITGAICEECSPVIPQCGKQIGGGDIAVFASRAGLGACWHPQCFVCSTCRELLVDLIYFYHAGKVYCGRHHAERLRPRCQACDEIIFSPECTEAEGRHWHMDHFCCFECEASLGGQRYVMRQSRPHCCACYEARHAEYCDGCGEHIGLDQGQMAYEGQHWHASERCFCCSRCGRALLGRPFLPRRGLIFCSRACSLGSEPMAPAHSRRSWSTSTVSTPLTASTASFSAVEGASETTTKGTNTEAAPAADPEEPTHFLRGAPHRHSMPELGLRSVPEPPLGPPSQPDPRPEDGAFGRQSAPRVSFRDPLVSEGGPRRTLSAPPAQRRRPRSPPPRGPMRRRRHRHHHDHHHHHHHHRCHFGRRRHHQCDLGSGSDSGSCSSSPSSSSSESSEEDGYFLGERIPLSPHLCRPVLAQDTAAETTNSPSPQLPGNSRPGISRQARDKNCIVA", "length": 627, "header": "tr|F6QKQ1-1|F6QKQ1_BOVIN Isoform 1 of Prickle planar cell polarity protein 3 OS=Bos taurus OX=9913 GN=PRICKLE3 PE=3 SV=2 CANONICAL=F6QKQ1-1" }, "locus": { "chromosome": "X", "start_pos": 87228434, "end_pos": 87219651, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000021427.6", "url": "https://www.ensembl.org/id/ENSBTAT00000021427.6" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000021427.6", "url": "https://www.ensembl.org/id/ENSBTAP00000021427.6" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [], "orthologs": [], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 1, "go_terms": [ { "name": "mitochondrion", "id": "GO:0005739", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005739", "evidence": [ { "database": "UniProtKB", "id": "F6QKQ1", "url": "https://www.uniprot.org/uniprotkb/F6QKQ1" } ], "pmid": "" } ] }, { "name": "Molecular Function", "total": 1, "go_terms": [ { "name": "zinc ion binding", "id": "GO:0008270", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008270", "evidence": [ { "database": "UniProtKB", "id": "F6QKQ1", "url": "https://www.uniprot.org/uniprotkb/F6QKQ1" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [ { "pdb_id": "AF-F6QKQ1-F1", "pdb_chain": "global", "start_pos": 1, "end_pos": 627, "overlap": "1.0", "method": "AlphaFold", "type": "alphafold", "resolution": -1.0, "url": "https://data.glygen.org/ln2downloads/pdb/current/AF-F6QKQ1-F1.pdb", "url_external": "https://alphafold.ebi.ac.uk/entry/F6QKQ1" } ], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "F6QKQ1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F6QKQ1" }, { "id": "PS50023", "database": "PROSITE", "url": "https://prosite.expasy.org/PS50023" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "LIM zinc-binding", "eco_id": "ECO_0000259", "start_pos": 184, "end_pos": 255, "start_aa": "Ala", "end_aa": "Arg", "glycosite_overlap": [] }, { "evidence": [ { "id": "F6QKQ1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F6QKQ1" }, { "id": "PS51303", "database": "PROSITE", "url": "https://prosite.expasy.org/PS51303" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "PET", "eco_id": "ECO_0000259", "start_pos": 74, "end_pos": 182, "start_aa": "Ser", "end_aa": "Thr", "glycosite_overlap": [] } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ], "tool_support": { "graph_view": "yes" } }, { "uniprot_canonical_ac": "F6QL83-1", "uniprot_ac": "F6QL83", "uniprot_id": "F6QL83_BOVIN", "mass": { "chemical_mass": 44375.0, "monoisotopic_mass": 44375.0 }, "refseq": { "ac": "NP_001193346", "name": "atypical chemokine receptor 5", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001193346" }, "gene_names": [ { "name": "GPR182", "type": "recommended", "evidence": [ { "id": "F6QL83", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F6QL83" } ] }, { "name": "GPR182", "type": "synonym", "evidence": [ { "id": "NP_001193346", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001193346" } ] } ], "protein_names": [ { "name": "G protein-coupled receptor 182", "type": "synonym", "evidence": [ { "id": "F6QL83", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F6QL83/entry#names_and_taxonomy" } ] }, { "name": "atypical chemokine receptor 5", "type": "synonym", "evidence": [ { "id": "NP_001193346", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001193346" } ] } ], "function": [], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Bos taurus", "taxid": 9913, "evidence": [ { "database": "UniProtKB", "id": "F6QL83", "url": "https://www.uniprot.org/uniprotkb/F6QL83" } ], "common_name": "Bovine", "glygen_name": "Bovine", "reference_species": "Bos taurus [9913]" } ], "gene": [ { "name": "GPR182", "url": "https://www.uniprot.org/uniprotkb/F6QL83", "locus": { "chromosome": "5", "start_pos": 56432151, "end_pos": 56443457, "strand": "+", "evidence": [ { "database": "Ensembl Gene", "id": "ENSBTAG00000039157", "url": "https://www.ensembl.org/id/ENSBTAG00000039157" } ] } } ], "crossref": [ { "id": "F6QL83", "url": "https://alphafold.ebi.ac.uk/entry/F6QL83", "database": "AlphaFoldDB", "categories": [] }, { "id": "ENSBTAG00000039157", "url": "https://bgee.org/?page=gene&gene_id=ENSBTAG00000039157", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "cd14988", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd14988", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "509554", "url": "https://www.ncbi.nlm.nih.gov/gene/509554", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR000276", "url": "https://www.ebi.ac.uk/interpro/entry/IPR000276", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR001350", "url": "https://www.ebi.ac.uk/interpro/entry/IPR001350", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR017452", "url": "https://www.ebi.ac.uk/interpro/entry/IPR017452", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR047143", "url": "https://www.ebi.ac.uk/interpro/entry/IPR047143", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "bta:509554", "url": "https://www.genome.jp/dbget-bin/www_bget?bta:509554", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "LYFFNHT", "url": "https://omabrowser.org/oma/group/LYFFNHT/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "F6QL83", "url": "https://www.orthodb.org/?gene=F6QL83", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR24226", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR24226", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR24226:SF0", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR24226:SF0", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00001", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00001", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "NP_001193346", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001193346", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "F6QL83", "url": "https://www.uniprot.org/uniprotkb/F6QL83", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "F6QL83-1", "url": "https://www.uniprot.org/uniprotkb/F6QL83-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MSATAGPSMAPTRDVGEIYNWTELLHFFNHTLPECHMELNENTKRVALFVLYLAIFVVGLVENLLVICVNWRGSARAGLLRLYVLNMAIADLGIILSLPVWMLEATLDYTWLWGSFSCRFTHYFYYANMYSSIFFLVCLSVDRYVTLTNASTSWQRHQHRGRRAVCAGVWVLSALIPLPEVVHIRLVDSFEPMCLFMAPFETYSTWATVVALSTTVLGFLLPLPLIAVFNVLTARRLRQTGQPEGRRHCLLVCAYIAVFVICWLPYHLTLLLLTLHGTHISLHCYLAHLLYFFYDIIDCFSMLHCVVNPILYNFLSPSFRGRLLNAVVHYLPKVQVREGRHASTSSSSSTQHSIIITKEGIQPPAAGPHQHPSLNFQAANTLPTSAPQSLVAS", "length": 393, "header": "tr|F6QL83-1|F6QL83_BOVIN Isoform 1 of G protein-coupled receptor 182 OS=Bos taurus OX=9913 GN=GPR182 PE=3 SV=1 CANONICAL=F6QL83-1" }, "isoforms": [ { "isoform_ac": "F6QL83-1", "url": "https://www.uniprot.org/uniprotkb/F6QL83/entry", "sequence": { "sequence": "MSATAGPSMAPTRDVGEIYNWTELLHFFNHTLPECHMELNENTKRVALFVLYLAIFVVGLVENLLVICVNWRGSARAGLLRLYVLNMAIADLGIILSLPVWMLEATLDYTWLWGSFSCRFTHYFYYANMYSSIFFLVCLSVDRYVTLTNASTSWQRHQHRGRRAVCAGVWVLSALIPLPEVVHIRLVDSFEPMCLFMAPFETYSTWATVVALSTTVLGFLLPLPLIAVFNVLTARRLRQTGQPEGRRHCLLVCAYIAVFVICWLPYHLTLLLLTLHGTHISLHCYLAHLLYFFYDIIDCFSMLHCVVNPILYNFLSPSFRGRLLNAVVHYLPKVQVREGRHASTSSSSSTQHSIIITKEGIQPPAAGPHQHPSLNFQAANTLPTSAPQSLVAS", "length": 393, "header": "tr|F6QL83-1|F6QL83_BOVIN Isoform 1 of G protein-coupled receptor 182 OS=Bos taurus OX=9913 GN=GPR182 PE=3 SV=1 CANONICAL=F6QL83-1" }, "locus": { "chromosome": "5", "start_pos": 56438521, "end_pos": 56437343, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000052364.4", "url": "https://www.ensembl.org/id/ENSBTAT00000052364.4" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000052513.3", "url": "https://www.ensembl.org/id/ENSBTAP00000052513.3" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [ { "id": "bta:509554", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?bta:509554", "resource": "KEGG Pathway" } ], "orthologs": [ { "uniprot_canonical_ac": "A0A4X1W8F6-1", "protein_name": "G protein-coupled receptor 182", "gene_name": "GPR182", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MSTTGPSVGPASDLGEIHNWTELLHFFNHTLPECHMELSEDTKRVALFVLYLAIFVVGLVENLLVICVNWHSSDRAGLLRPYVLNMAIADLGIVLSLPVWMLEVTLDYTWLWGSFSCRFTHYFYFVNMYSSIFFLVCLSIDRYVTLTNAFPTWQRHQHRGRRAVCMGVWVLAALIPLPEVVHIQLVDSFEPMCLFMAPFETYSTWALVAALSTTVLGFLLPFPLMVVFNVLTACRLRQAGQPEGRRHCRLVCAYITVFVICWLPYHVTLLLITLHGTHISLHCYLAHLLYFFYDIIDCFSMLHCVVNPILYNFLSPSFQGRLLNAVVHYLPKVQDREGRHASSSSSTQHSIVITKEGIQPPAAGPHHRV", "length": 369 }, "evidence": [ { "id": "F6QL83", "url": "https://omabrowser.org/oma/group/F6QL83/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "A0A8V1A9Q5-1", "protein_name": "G protein-coupled receptor 182", "gene_name": "GPR182", "tax_id": 9031, "organism": "Gallus gallus", "sequence": { "sequence": "MAEATAAPSETPTAPSEFGEYHNLSELFHLLNYTYTSCEFSLDENAKRVAVFVLYLAIFVVGLVENLLVVWVNWQTRSSRSLVNLYVLHMAIADLGVLLSLPVWMLEVMLDYTWLWGSFLCRFTHYFYLANMYASIFFLTCLSVDRYVSLRGSSPFWHRHQHLARRIICTSVWVLAAAIPFVEVSHMQLVNTGDPICIFMAPFETYDEWALAVSLATTAVGFLIPFSIIVVFNVLTARLVRRSKPEEGRRHCLLIYAYIAAFLLSWLPFHILLTLLTLDGTHIVLHCSFAHFLYFFYDIIDCLTLLHCVLNPILYNFLSKSFRSKLISAVVKYVPKDAAGQKGAEGSSSSTQHSIVIAKDGSAPS", "length": 365 }, "evidence": [ { "id": "F6QL83", "url": "https://omabrowser.org/oma/group/F6QL83/", "database": "OMA" } ], "glygen_name": "Chicken", "common_name": "Chicken" }, { "uniprot_canonical_ac": "G3HW25-1", "protein_name": "G-protein coupled receptor 182", "gene_name": "Gpr182", "tax_id": 10029, "organism": "Cricetulus griseus", "sequence": { "sequence": "MSVKSSPGPSPTSAPGNDFGEIHNWTELLHFFNHTFSDCHTEFNENAKQVVLFVVYLAIFVVGLVENVLVICVNWRRSGRAGLLNLYVLNIAIADLGIVLSLPVWMLEVMLDYTWLWGSFSCRFTHYFYLANMYSSIFFLTCLSIDRYVSLANPSPSWQRHQHRVRRAVCAGVWVLSAIIPLPEVVHIQLMDGSEPMCLFLAPFETYSTWALAVALSATILGFLLPFPLIAVFNILTACRLRKQGQPESRRHCLLLWAYIAVFVICWLPYHVTMLLLTLHATHIFLHCHLVNLLYFFYEIIDCFSMLHCVANPILYNFLSPSFRGRLLSIVVRYLPKEQARAAGRRASSSSSTQHSIIITKEGSLPAAELHPHPTRNSGASSPPRNASSTFCNSIAS", "length": 397 }, "evidence": [ { "id": "F6QL83", "url": "https://omabrowser.org/oma/group/F6QL83/", "database": "OMA" } ], "glygen_name": "Hamster", "common_name": "Chinese hamster" }, { "uniprot_canonical_ac": "O15218-1", "protein_name": "Atypical chemokine receptor 5", "gene_name": "ACKR5", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": 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"total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ], "tool_support": { "graph_view": "yes" } }, { "uniprot_canonical_ac": "F6QMY2-1", "uniprot_ac": "F6QMY2", "uniprot_id": "F6QMY2_BOVIN", "mass": { "chemical_mass": 22851.0, "monoisotopic_mass": 22851.0 }, "refseq": {}, "gene_names": [ { "name": "THY1", "type": "recommended", "evidence": [ { "id": "F6QMY2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F6QMY2" } ] } ], "protein_names": [ { "name": "Thy-1 membrane glycoprotein", "type": "recommended", "evidence": [ { "id": "F6QMY2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F6QMY2/entry#names_and_taxonomy" } ] }, { "name": "Thy-1 antigen", "type": "synonym", "evidence": [ { "id": "F6QMY2", 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[ "Protein Classification" ] }, { "id": "PTHR19226", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR19226", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR19226:SF2", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR19226:SF2", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00047", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00047", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "F6QMY2", "url": "https://www.uniprot.org/uniprotkb/F6QMY2", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "F6QMY2-1", "url": "https://www.uniprot.org/uniprotkb/F6QMY2-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": 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"PTHR23068:SF6", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR23068:SF6", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00855", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00855", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "R-BTA-9937850", "url": "https://www.reactome.org/PathwayBrowser/#R-BTA-9937850", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "NP_001069324", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001069324", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0AAA9T2P3", "url": "https://www.uniprot.org/uniprotkb/A0AAA9T2P3", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0AAA9T2P3-1", "url": "https://www.uniprot.org/uniprotkb/A0AAA9T2P3-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "F6QPT2", "url": "https://www.uniprot.org/uniprotkb/F6QPT2", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "F6QPT2-1", "url": "https://www.uniprot.org/uniprotkb/F6QPT2-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MEPRAGCRLPVRVEQVVNGALLVTASCGERSFAGILLDCTKKSGLFGLPPLAPLTQAQDAPVNGCHGPSPAEGDAEAMPLGTGPPAPEGGDGAPEPPLPPVPPLPAGSLPPFPPYFEGAPFPPPLWLRNTYRQWVPQPPPRGVKRTRRRLSRNRDPGRLALSPIRLRPRQVLCEKCKSTQSPPEASPGPPAAPRPRREPRKPEDPDGGGDAAAAKKSRRERREEARPGVPRSPAIKISYSTPQGTGEVVEIPPRVHGSLEPFCPPPASPGGLDPEPPRDRPAAGAPASIPKLKLTRPLPPGATPPPPKIRLKPRRLGAGKQEPVYRAELVQELKGRGLPADGATHRGGLADSSSASSGEDDDCKGCPRGAHGPDNAGLAFLATCPGRSGCTSELAWSSDSLDESKSSGSDGTLPDTCDLSPGDGVPSSSKGTRPTVPPLTVRLHTQSVSKCVTEDGRTVAVGDIVWGKVHGFPWWPARVLDISLSQKEDGEPSWQEAKVSWFGSPTTSFLSTSKLSPFSEFFKLRFNRKKKGMYRKAITEAANAAQHVAPEIRELLTQFET", "length": 561, "header": "tr|F6QPT2-1|F6QPT2_BOVIN Isoform 1 of PWWP domain containing 2B OS=Bos taurus OX=9913 GN=PWWP2B PE=4 SV=1 CANONICAL=F6QPT2-1" }, "isoforms": [ { "isoform_ac": "A0AAA9T2P3-1", "url": "https://www.uniprot.org/uniprotkb/A0AAA9T2P3/entry", "sequence": { "sequence": "MPSSGDSRLQKPGVRRAVTRRGPRRALPDPRTPGRGRGRSGLFGLPPLAPLTQAQDAPVNGCHGPSPAEGDAEAMPLGTGPPAPEGGDGAPEPPLPPVPPLPAGSLPPFPPYFEGAPFPPPLWLRNTYRQWVPQPPPRGVKRTRRRLSRNRDPGRLALSPIRLRPRQVLCEKCKSTQSPPEASPGPPAAPRPRREPRKPEDPDGGGDAAAAKKSRRERREEARPGVPRSPAIKISYSTPQGTGEVVEIPPRVHGSLEPFCPPPASPGGLDPEPPRDRPAAGAPASIPKLKLTRPLPPGATPPPPKIRLKPRRLGAGKQEPVYRAELVQELKGRGLPADGATHRGGLADSSSASSGEDDDCKGCPRGAHGPDNAGLAFLATCPGRSGCTSELAWSSDSLDESKSSGSDGTLPDTCDLSPGDGVPSSSKGTRPTVPPLTVRLHTQSVSKCVTEDGRTVAVGDIVWGKVHGFPWWPARVLDISLSQKEDGEPSWQEAKVSWFGSPTTSFLSTSKLSPFSEFFKLRFNRKKKGMYRKAITEAANAAQHVAPEIRELLTQFET", "length": 558, "header": "tr|A0AAA9T2P3-1|A0AAA9T2P3_BOVIN Computationally mapped isoform of PWWP domain containing 2B OS=Bos taurus OX=9913 GN=PWWP2B PE=4 SV=1 CANONICAL=F6QPT2-1" }, "locus": { "chromosome": "26", "start_pos": 51984862, "end_pos": 51973837, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000132517.2", "url": "https://www.ensembl.org/id/ENSBTAT00000132517.2" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000092003.2", "url": "https://www.ensembl.org/id/ENSBTAP00000092003.2" } ] } }, { "isoform_ac": "F6QPT2-1", "url": "https://www.uniprot.org/uniprotkb/F6QPT2/entry", "sequence": { "sequence": "MEPRAGCRLPVRVEQVVNGALLVTASCGERSFAGILLDCTKKSGLFGLPPLAPLTQAQDAPVNGCHGPSPAEGDAEAMPLGTGPPAPEGGDGAPEPPLPPVPPLPAGSLPPFPPYFEGAPFPPPLWLRNTYRQWVPQPPPRGVKRTRRRLSRNRDPGRLALSPIRLRPRQVLCEKCKSTQSPPEASPGPPAAPRPRREPRKPEDPDGGGDAAAAKKSRRERREEARPGVPRSPAIKISYSTPQGTGEVVEIPPRVHGSLEPFCPPPASPGGLDPEPPRDRPAAGAPASIPKLKLTRPLPPGATPPPPKIRLKPRRLGAGKQEPVYRAELVQELKGRGLPADGATHRGGLADSSSASSGEDDDCKGCPRGAHGPDNAGLAFLATCPGRSGCTSELAWSSDSLDESKSSGSDGTLPDTCDLSPGDGVPSSSKGTRPTVPPLTVRLHTQSVSKCVTEDGRTVAVGDIVWGKVHGFPWWPARVLDISLSQKEDGEPSWQEAKVSWFGSPTTSFLSTSKLSPFSEFFKLRFNRKKKGMYRKAITEAANAAQHVAPEIRELLTQFET", "length": 561, "header": "tr|F6QPT2-1|F6QPT2_BOVIN Isoform 1 of PWWP domain containing 2B OS=Bos taurus OX=9913 GN=PWWP2B PE=4 SV=1 CANONICAL=F6QPT2-1" }, "locus": { "chromosome": "26", "start_pos": 51984862, "end_pos": 51975352, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000026000.7", "url": "https://www.ensembl.org/id/ENSBTAT00000026000.7" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000026000.5", "url": "https://www.ensembl.org/id/ENSBTAP00000026000.5" } ] } } ], "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "other", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 303, "start_aa": "Thr", "end_pos": 303, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr303", "evidence": [ { "id": "", "database": "GlyGen", "url": "https://data.glygen.org/" } ], "filter_code": "000000000000000010000.00000000001000.0.01000" } ], "phosphorylation": [], "glycation": [], "keywords": [ "glycoprotein", "glycoprotein_predicted" ], "publication": [], "pathway": [ { "id": "bta:524314", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?bta:524314", "resource": "KEGG Pathway" }, { "id": "R-BTA-9937850", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-BTA-9937850", "resource": "Reactome", "description": "NuRD complex assembly" } ], "orthologs": [ { "uniprot_canonical_ac": "A0A0R4IGL9-1", "protein_name": "PWWP domain-containing protein 2B", "gene_name": "pwwp2b", "tax_id": 7955, "organism": "Danio rerio", "sequence": { "sequence": "MQASPEELRAGSRLPVTVEQILNDTLVVTLRYREKSFTGILLDCSRKTGLFCLPDVVGKTEEPLILRPDCEVLSEESSSEPVSQPTQRPKDENTEPEESPAPVPIPLQPGQHTYPPYFEGAPFPQPIWVRHTYNQWVPQPPPRPIKRKKRRSRDAGRLAISTIRLRPRQVLCEKCKNTLNSDEDSKDGPTLPKTSRKENSPHAEDDNTKTTSAKRKDDGEHNNRESKRREDSTVYDGKRFRKDKKEEEKFPSGDVIPHSPVIKISYSTPQGKGEVMKIPSRVHGSVKPFCPKQLLQNGHGDRDSSKETPKKLQPPMDAIRTGLTISIPKLKLPKLPSPDAQSPKIRLRSRAEGAEQMSVYEAELVDGARRRSPRVPNSGLPQSEDAEDKNSLELWSGSCGGEVERHGDLTLLINFRKRKADSSSLSVCSSDSLDESKSFSSDGTSPELCDLAPGDDISVSSSSQGEGKTVPPLTVRLHTRSMSKCVTEDGHAVTVGDVVWGKIHGFPWWPARILSISGTRREDGEVDAPWPEAKVSWFGSPTTSELSVAKLSPFREFFRSRFNRKKKGMYRRAIMEAAKAVGHMGAEITSLLAHCET", "length": 597 }, "evidence": [ { "id": "F6QPT2", "url": "https://omabrowser.org/oma/group/F6QPT2/", "database": "OMA" } ], "glygen_name": "Zebrafish", "common_name": "Zebrafish" }, { "uniprot_canonical_ac": "A0A8V0X5Z5-1", "protein_name": "PWWP domain containing 2B", "gene_name": "PWWP2B", "tax_id": 9031, "organism": "Gallus gallus", "sequence": { "sequence": "MPHYILGCGSFLWYVFWFCESSALAAQPSRGAPSTTLTASLRLSPCSRSGLFCQPSSLPKPEEPPAAACVPAARDPTPGETQPQPGDDQVPPLLPAPPGSLPPYPPYFEGAPFPRPLWLRHTYSQWVPQPPPRAIKRTRRRLSRNRDPGRLIMSTIRLRPRQVLCEKCKNTLNPEDENAAGQNAKTRRKLSIQDKEQKKHSDSECLEKRNKREKREDDRFAGELVHRTPVIKISYSTPQGKGEVVKIPSRVHGSVKPFCPERLLQNGEEDQGEVGDAEQCREPKCCADKAAGGQLASIPKLKLTRPAHPSADAPPPKIRLKPHRINDGQSVSIYKAELIDEINVLQDSREANPGAFYTSEPTDRGLAEISSGSSGEDDDFKRFPQGKDGHDNLAFLMNYRKRKADSSSLSVCSNDSLDESKSSSSEVTSPEMCDFLPGDDASVSSSSKDERKIVPPLTVRLHTQSVSKCVTEDGRTVAVGDIVWGKIHGFPWWPARVLDINLSQKENGEPSWREAKVSWFGSPTTSFLSVSKLSPFSEFFKLRFNRKKKGMYRKAITEAAKAVEHLTPEIRDLLTQFET", "length": 579 }, "evidence": [ { "id": "F6QPT2", "url": "https://omabrowser.org/oma/group/F6QPT2/", "database": "OMA" } ], "glygen_name": "Chicken", "common_name": "Chicken" }, { "uniprot_canonical_ac": "E9Q9M8-1", "protein_name": "PWWP domain-containing protein 2B", "gene_name": "Pwwp2b", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MEPRAGCRLPVRVEQVVNGALVVTVSCGERSFAGILLDCTKKSGLFGLSPSTLLPLADNSSAVSCHGQAPEEGTGEVMQLETGPLHPHHKDPEKDQPPKTAVSEPPPPLIPPVPAGNLPPFPPYFEGAPFPHPLWLRNTYQQWVPQPPPRTIKRTRRRLSRNRDPGRLILSTIRLRPRQVLCEKCKSTVSPQEASPSPLNTPKPRRRLGSGPDSEHRKPEEPEDSAVIATAAPRRSKREKREEDRVAGERVPRSPVIKISYSTPQGKGEVVKIPSRVHGSVEPFCPQQSLQNGSQDSEVSRDVEPRGGGDRPPSGSSASIPKLKLTRPVPPISDLPPPKIRLKPHRLGDGEHEPLYRAELVEELNGCPRGPLVSSPALFADGSSHGLEDLSSGSSGEDDDLKRFPQGKHGRDGLAFLVDCPGRRTDCTSESVCSTDSLDELKSSGSEVTSPDTGDLSSGDSASVPSSSADTRQTVPPLTVRLHTQSVSRCVTEDGRTVAVGDIVWGKIHGFPWWPARVLDISLGQKEDGEPSWQEAKVSWFGSPTTSFLSISKLSPFSEFFKLRFNRKKKGMYRKAITEAANATQHVAPEIRELLTQFEM", "length": 600 }, "evidence": [ { "id": "F6QPT2", "url": "https://omabrowser.org/oma/group/F6QPT2/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "F7FFV6-1", "protein_name": "PWWP domain containing 2B", "gene_name": "Pwwp2b", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MEPRAGCRLPVRVEQVVNGALVVTVSCGERSFAGILLDCTKKSGLFGLSPSTLLPLADNSSAISCHGQVPEEGTGEVMQLETGPLPPHHQDPEKDQPPKTAVPEPPPPLIPPVPAGNLPPFPPYFEGAPFPHPLWLRNTYQQWVPQPPPRAIKRTRRRLSRNRDPGRLILSTIRLRPRQVLCEKCKSTVSPQDASPGPLNTPKPRRRLGSGPDSEYRKPEEPEDSAVIAMAAPRRNKREKREEDRVAGERIPRSPVIKISYSTPQGKGEVVKIPSRVHGSVEPFCPQQSLQNGSQDSEVSRDGETKGGGDRPSSGLSASIPKLKLTRPVPPVSDLPPPKIRLKPHRLGNGEHEPLYRAELVEELNGCPRGPLASSPALFADGSTHGLEDLSSGSSGEDDDLKRFPQGKHGRDGLAFLVDCPGRRADCTSESVCSSTDSLDELKSSGSEVTSPDTGDLSSGDSASVPSSSADTRQTVPPLTVRLHTQSVSQCVTEDGRTVAVGDIVWGKIHGFPWWPARVLDISLGQKEDGEPSWQEAKVSWFGSPTTSFLSISKLSPFSEFFKLRFNRKKKGMYRKAITEAANATQHVAPEIRELLTQFEM", "length": 601 }, "evidence": [ { "id": "F6QPT2", "url": "https://omabrowser.org/oma/group/F6QPT2/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "I3LJE6-1", "protein_name": "PWWP domain containing 2B", "gene_name": "PWWP2B", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MEPRVGCRLPVRVEQVVNGALLVTVSCGERSFAGILLDCTKKSGLFGLPPTAPLPQAQEPPVNGCQGPTPTEGAAEAMQPGTGPPPPPTGDQPTGTASPELPPPLVPPLPAGSLPPFPPYFEGAPFPPPLWLRNTYRQWVPQPPPRGIKRTRRRLSRHRDPGCLALSPILLRPRQVLCKKCQSALSPPEASPGPPAAPRPRRELRKPEDPDGGGDTAAAGKRSKRERPEEAGARVPRSPVIKISYSTPQGTGEVVQIPSRVHGSLEPFCPPQALPGSQDPEAPRDRPPAAIPKLKLTRPLPPGASPPPPKIRLKPRRGGAGQQEPVYRAELVEELNGRGCGALADGPAGPGLADLSSGSSGEDDDCKGCPQGKRRRQGLAFLATCPSGAGCASESLWSSDSLDESKSSSSEVTSPDTCDLSSGDGASAPSSSKDARPTVPPLTVRLHTQSVSKCVTEDGRTVAVGDIVWGKVHGFPWWPARVLDISLSQKEDGEPSWREAKVSWFGSPTTSFLSLSKLSPFSESFKLRFNRKKKGMYRKAITEAASAAQHVAPEIRELLTQFET", "length": 564 }, "evidence": [ { "id": "F6QPT2", "url": "https://omabrowser.org/oma/group/F6QPT2/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "Q6NUJ5-1", "protein_name": "PWWP domain-containing protein 2B", "gene_name": "PWWP2B", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MEPRAGCRLPVRVEQVVNGALVVTVSCGERSFAGILLDCTKKSGLFGLPPLAPLPQVDESPVNDSHGRAPEEGDAEVMQLGSSSPPPARGVQPPETTRPEPPPPLVPPLPAGSLPPYPPYFEGAPFPHPLWLRDTYKLWVPQPPPRTIKRTRRRLSRNRDPGRLILSTIRLRPRQVLCEKCKSTLSPPEASPGPPAAPRARRRLGSGPDRELRKPEEPENGEPTAAATARRSKRERREEDRAPAEQVPRSPVIKISYSTPQGKGEVVKIPSRVHGSLEPFRPQQAPQDDGSQDPEVLDRESRDRPSCAPSASIPKLKLTRPVPAGADLPPPKIRLKPHRLGDSEHEPVYRAELVGELNGYLRDSSPAPCADGPAGGLADLSSGSSGEDDDFKSCPQGPQGREGLAFLVSCPEGRADCASESACSSDSLDEARSSGSEGTPADTGDLSPGHGASAPSVSREARQTVPPLTVRLHTQSVSECITEDGRTVAVGDIVWGKIHGFPWWPARVLDISLGQKEDGEPSWREAKVSWFGSPTTSFLSISKLSPFSEFFKLRFNRKKKGMYRKAITEAANAARHVAPEIRELLTQFET", "length": 590 }, "evidence": [ { "id": "F6QPT2", "url": "https://omabrowser.org/oma/group/F6QPT2/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" } ], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 2, "go_terms": [ { "name": "nucleus", "id": "GO:0005634", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005634", "evidence": [ { "database": "UniProtKB", "id": "F6QPT2", "url": "https://www.uniprot.org/uniprotkb/F6QPT2" } ], "pmid": "" }, { "name": "nucleoplasm", "id": "GO:0005654", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005654", "evidence": [ { "database": "UniProtKB", "id": "F6QPT2", "url": "https://www.uniprot.org/uniprotkb/F6QPT2" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 1, "go_terms": [ { "name": "DNA-templated transcription", "id": "GO:0006351", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006351", "evidence": [ { "database": "UniProtKB", "id": "F6QPT2", "url": "https://www.uniprot.org/uniprotkb/F6QPT2" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [ { "pdb_id": "AF-F6QPT2-F1", "pdb_chain": "global", "start_pos": 1, "end_pos": 561, "overlap": "1.0", "method": "AlphaFold", "type": "alphafold", "resolution": -1.0, "url": "https://data.glygen.org/ln2downloads/pdb/current/AF-F6QPT2-F1.pdb", "url_external": "https://alphafold.ebi.ac.uk/entry/F6QPT2" } ], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "F6QPT2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F6QPT2" }, { "id": "PS50812", "database": "PROSITE", "url": "https://prosite.expasy.org/PS50812" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "PWWP", "eco_id": "ECO_0000259", "start_pos": 461, "end_pos": 521, "start_aa": "Val", "end_aa": "Phe", "glycosite_overlap": [] } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" }, { "name": "homologset.oma", "label": "OMA Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [ 303 ], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 1 }, { "field": "total_sites", "count": 1 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 1 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "exact_sites", "count": 1 }, { "field": "exact_o_linked_sites", "count": 1 }, { "field": "fuzzy_sites", "count": 0 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_pos", "start_aa", "end_pos", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 1 }, { "field": "total_sites", "count": 1 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 1 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "exact_sites", "count": 1 }, { "field": "exact_o_linked_sites", "count": 1 }, { "field": "fuzzy_sites", "count": 0 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_pos", "start_aa", "end_pos", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ], "tool_support": { "graph_view": "yes" } }, { "uniprot_canonical_ac": "F6QPX6-1", "uniprot_ac": "F6QPX6", "uniprot_id": "F6QPX6_BOVIN", "mass": { "chemical_mass": 30165.0, "monoisotopic_mass": 30165.0 }, "refseq": { "ac": "XP_024833150", "name": "BRI3-binding protein isoform X1", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_024833150" }, "gene_names": [ { "name": "BRI3BP", "type": "recommended", "evidence": [ { "id": "F6QPX6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F6QPX6" } ] }, { "name": "BRI3BP", "type": "synonym", "evidence": [ { "id": "XP_024833150", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_024833150" } ] } ], "protein_names": [ { "name": "BRI3 binding protein", "type": "synonym", "evidence": [ { "id": "F6QPX6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F6QPX6/entry#names_and_taxonomy" } ] }, { "name": "BRI3-binding protein isoform X1", "type": "synonym", "evidence": [ { "id": "XP_024833150", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_024833150" } ] } ], "function": [], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Bos taurus", "taxid": 9913, "evidence": [ { "database": "UniProtKB", "id": "F6QPX6", "url": "https://www.uniprot.org/uniprotkb/F6QPX6" } ], "common_name": "Bovine", "glygen_name": "Bovine", "reference_species": "Bos taurus [9913]" } ], "gene": 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"total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ], "tool_support": { "graph_view": "yes" } }, { "uniprot_canonical_ac": "F6QSX2-1", "uniprot_ac": "F6QSX2", "uniprot_id": "F6QSX2_BOVIN", "mass": { "chemical_mass": 50671.0, "monoisotopic_mass": 50671.0 }, "refseq": {}, "gene_names": [], "protein_names": [ { "name": "Ankyrin repeat and sterile alpha motif domain containing 4B", "type": "synonym", "evidence": [ { "id": "F6QSX2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F6QSX2/entry#names_and_taxonomy" } ] } ], "function": [ { "annotation": "Plays a central role during spermatogenesis by repressing transposable elements and preventing their mobilization, which is essential for the germline integrity. Acts via the piRNA metabolic process, which mediates the repression of transposable elements during meiosis by forming complexes composed of piRNAs and Piwi proteins and governs the methylation and subsequent repression of transposons. Its association with pi-bodies suggests a participation in the primary piRNAs metabolic process. Required prior to the pachytene stage to facilitate the production of multiple types of piRNAs, including those associated with repeats involved in the regulation of retrotransposons. May act by mediating protein-protein interactions during germ cell maturation.", "evidence": [ { "database": "UniProtKB", "id": "F6QSX2", "url": "https://www.uniprot.org/uniprotkb/F6QSX2#function" }, { "database": "UniProtKB", "id": "ARBA00025297", "url": "https://www.uniprot.org/uniprotkb/ARBA00025297#function" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Bos taurus", "taxid": 9913, "evidence": [ { "database": "UniProtKB", "id": "F6QSX2", "url": "https://www.uniprot.org/uniprotkb/F6QSX2" } ], "common_name": "Bovine", "glygen_name": "Bovine", "reference_species": "Bos taurus [9913]" } ], "gene": [ { "name": "", "url": "https://www.uniprot.org/uniprotkb/F6QSX2", "locus": {} } ], "crossref": [ { "id": "F6QSX2", "url": "https://alphafold.ebi.ac.uk/entry/F6QSX2", "database": "AlphaFoldDB", "categories": [] }, { "id": "cd09587", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd09587", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "IPR001660", "url": "https://www.ebi.ac.uk/interpro/entry/IPR001660", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR002110", "url": "https://www.ebi.ac.uk/interpro/entry/IPR002110", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR013761", "url": "https://www.ebi.ac.uk/interpro/entry/IPR013761", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR036770", "url": "https://www.ebi.ac.uk/interpro/entry/IPR036770", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR037601", "url": "https://www.ebi.ac.uk/interpro/entry/IPR037601", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "PTHR24161", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR24161", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR24161:SF20", 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"MDLKTQQGKERLYKKAASLTSCSAWRVIFGKASESRKMSTRYHQAASDSYLELLKEATKRDLNLSDEDGMTPTLLAAYHGNLEALEIICSRGGDPNRCDIWGNTPLHYAASNGHAHCVSFLINFGANIFALDNDLQSPLDAAASREQNECVALLDKAATAQNIMNPKKVTRQKEQAQKNVKKQIKECERLQEKHQNKMARTYSKEESGTLSSSKGTFSRSVLSNASASNTFGSLSKGIKDTLKLKFKKNKDTAEQLGNESRSGQKNVMEVFREDEEDELSGDFIEKLQFSEKGDSCMQHESILNRPGLGNVVFGRNRIFSPEDISDSRRELGFTMPSELLQRQGEAEADEEGEENHHEDDLPWDEDEVEWEEDVVDATPLEVFLQSHYLEEFLPIFMREQIDLEALLLCSDEDLQSIQMQLGPRKKVLNAINRRKQVLQQPGQLVDTNL", "length": 449, "header": "tr|F6QSX2-1|F6QSX2_BOVIN Isoform 1 of Ankyrin repeat and sterile alpha motif domain containing 4B OS=Bos taurus OX=9913 GN= PE=4 SV=1 CANONICAL=F6QSX2-1" }, "isoforms": [ { "isoform_ac": "F6QSX2-1", "url": "https://www.uniprot.org/uniprotkb/F6QSX2/entry", "sequence": { "sequence": 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], "pmid": "" }, { "name": "brush border assembly", "id": "GO:1904970", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:1904970", "evidence": [ { "database": "UniProtKB", "id": "F6QSX2", "url": "https://www.uniprot.org/uniprotkb/F6QSX2" } ], "pmid": "" }, { "name": "protein-containing complex assembly", "id": "GO:0065003", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0065003", "evidence": [ { "database": "UniProtKB", "id": "F6QSX2", "url": "https://www.uniprot.org/uniprotkb/F6QSX2" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 224, "end_pos": 226, "annotation": "n_glycosylation_sequon" }, { "start_pos": 258, "end_pos": 260, "annotation": "n_glycosylation_sequon" }, { "start_pos": 63, "end_pos": 65, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": 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"reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "F6QUX2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F6QUX2" }, { "id": "PS51968", "database": "PROSITE", "url": "https://prosite.expasy.org/PS51968" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "Grh/CP2 DB", "eco_id": "ECO_0000259", "start_pos": 314, "end_pos": 552, "start_aa": "Ser", "end_aa": "Ile", "glycosite_overlap": [] } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 164, "end_pos": 166 }, { "start_pos": 470, "end_pos": 472 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ], "tool_support": { "graph_view": "yes" } }, { "uniprot_canonical_ac": "F6QW76-1", "uniprot_ac": "F6QW76", "uniprot_id": "F6QW76_BOVIN", "mass": { "chemical_mass": 78352.0, "monoisotopic_mass": 78352.0 }, "refseq": {}, "gene_names": [ { "name": "RASGRP3", "type": "recommended", "evidence": [ { "id": "F6QW76", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F6QW76" } ] } ], "protein_names": [ { "name": "RAS guanyl releasing protein 3", "type": "synonym", "evidence": [ { "id": "F6QW76", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F6QW76/entry#names_and_taxonomy" } ] } ], "function": [], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Bos taurus", "taxid": 9913, "evidence": [ { "database": "UniProtKB", "id": "F6QW76", "url": "https://www.uniprot.org/uniprotkb/F6QW76" } ], "common_name": "Bovine", "glygen_name": "Bovine", "reference_species": "Bos taurus [9913]" } ], "gene": [ { "name": "RASGRP3", "url": "https://www.uniprot.org/uniprotkb/F6QW76", "locus": { "chromosome": "11", "start_pos": 16114724, "end_pos": 16067572, "strand": "-", "evidence": [ { "database": "Ensembl Gene", "id": "ENSBTAG00000008006", "url": "https://www.ensembl.org/id/ENSBTAG00000008006" } ] } } ], "crossref": [ { "id": "F6QW76", "url": "https://alphafold.ebi.ac.uk/entry/F6QW76", "database": "AlphaFoldDB", "categories": [] }, { "id": "ENSBTAG00000008006", "url": "https://bgee.org/?page=gene&gene_id=ENSBTAG00000008006", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "cd00051", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd00051", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "cd00155", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd00155", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "cd06224", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd06224", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "cd20862", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd20862", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "IPR000651", "url": "https://www.ebi.ac.uk/interpro/entry/IPR000651", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR001895", "url": "https://www.ebi.ac.uk/interpro/entry/IPR001895", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR002048", "url": "https://www.ebi.ac.uk/interpro/entry/IPR002048", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR002219", "url": "https://www.ebi.ac.uk/interpro/entry/IPR002219", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR008937", "url": "https://www.ebi.ac.uk/interpro/entry/IPR008937", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR011992", "url": "https://www.ebi.ac.uk/interpro/entry/IPR011992", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR018247", "url": "https://www.ebi.ac.uk/interpro/entry/IPR018247", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR020454", "url": "https://www.ebi.ac.uk/interpro/entry/IPR020454", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR023578", "url": "https://www.ebi.ac.uk/interpro/entry/IPR023578", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR036964", "url": "https://www.ebi.ac.uk/interpro/entry/IPR036964", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR046349", "url": "https://www.ebi.ac.uk/interpro/entry/IPR046349", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "QNRVTHR", "url": "https://omabrowser.org/oma/group/QNRVTHR/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "A0A3Q1LSU3", "url": "https://www.orthodb.org/?gene=A0A3Q1LSU3", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR23113", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR23113", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR23113:SF178", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR23113:SF178", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00130", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00130", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF00617", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00617", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF13499", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF13499", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "R-BTA-1169092", "url": "https://www.reactome.org/PathwayBrowser/#R-BTA-1169092", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "R-BTA-5673001", "url": "https://www.reactome.org/PathwayBrowser/#R-BTA-5673001", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "A0A3Q1LSU3", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1LSU3", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A3Q1LSU3-1", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1LSU3-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "F6QW76", "url": "https://www.uniprot.org/uniprotkb/F6QW76", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "F6QW76-1", "url": "https://www.uniprot.org/uniprotkb/F6QW76-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MGSSGLGKAATLDELLSTCIEMFDDNGELNNSYLPRIVLLMHRWYLSSTELAEKLLCIYRNASGESCDEFRLKICYFMRYWIVKFPAEFNLDLGLIRMTEEFREVASQLGYEKHTSLIDISSIPSYDWMRRVTQRKKVSKKGKACLLFDHLEPIELAEHLTFLEHKSFRRISFTDYQSYVIHGCLENNPTLERSIALFNGISKWVQLMVLSKPTPQQRAEVITKFINVAKKLLQLKNFNTLMAVVGGLSHSSISRLKETHSHLSSEVTKNWNEMMELVSSNGNYCNYRKAFADCDGFKIPILGVHLKDLIAVHVIFPDWTEENKVNIVKMHQLSVTLSELVSLQNASHHLEPNLDLINLLTLSLDLYHTEDDIYKLSLVLEPRNSKSQPTSPTTPTKPVVPLEWASGVMPKPDPTVINKHIRKLVESVFRNYDHDHDGYISQEDFESIAANFPFLDSFCVLDKDQDGLISKDEMMAYFLRAKSQLHCKMGPGFVHNFQEMTYLKPTFCEHCAGFLWGIIKQGYKCKDCGANCHKQCKDLLVLACRRFARAPSLGSSHGSLPGSPSLPPVQDEVFEFPGVTAGHRDLDSRAITLVTGSSGKISVRLQRATTSQATQTEPVWSEAGWGDSGSHTFPKMRSKFHDKAAKDKGFAKWENEKPRVQAGVDVVDRGTTFEPDQDEADMDETKQDGEDG", "length": 692, "header": "tr|F6QW76-1|F6QW76_BOVIN Isoform 1 of RAS guanyl releasing protein 3 OS=Bos taurus OX=9913 GN=RASGRP3 PE=3 SV=1 CANONICAL=F6QW76-1" }, "isoforms": [ { "isoform_ac": "A0A3Q1LSU3-1", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1LSU3/entry", "sequence": { "sequence": "MGSSGLGKAATLDELLSTCIEMFDDNGELNNSYLPRIVLLMHRWYLSSTELAEKLLCIYRNASGESCDEFRLKICYFMRYWIVKFPAEFNLDLGLIRMTEEFREVASQLGYEKHTSLIDISSIPSYDWMRRVTQRKKVSKKGKACLLFDHLEPIELAEHLTFLEHKSFRRISFTDYQSYVIHGCLENNPTLERSIALFNGISKWVQLMVLSKPTPQQRAEVITKFINVAKKLLQLKNFNTLMAVVGGLSHSSISRLKETHSHLSSEVTKNWNEMMELVSSNGNYCNYRKAFADCDGFKIPILGVHLKDLIAVHVIFPDWTEENKVNIVKMHQLSVTLSELVSLQNASHHLEPNLDLINLLTLSLDLYHTEDDIYKLSLVLEPRNSKSPTSPTTPTKPVVPLEWASGVMPKPDPTVINKHIRKLVESVFRNYDHDHDGYISQEDFESIAANFPFLDSFCVLDKDQDGLISKDEMMAYFLRAKSQLHCKMGPGFVHNFQEMTYLKPTFCEHCAGFLWGIIKQGYKCKDCGANCHKQCKDLLVLACRRFARAPSLGSSHGSLPGSPSLPPVQDEVFEFPGVTAGHRDLDSRAITLVTGSSGKISVRLQRATTSQATQTEPVWSEAGWGDSGSHTFPKMRSKFHDKAAKDKGFAKWENEKPRVQAGVDVVDRGTTFEPDQDEADMDETKQDGE", "length": 689, "header": "tr|A0A3Q1LSU3-1|A0A3Q1LSU3_BOVIN Computationally mapped isoform of RAS guanyl releasing protein 3 OS=Bos taurus OX=9913 GN=RASGRP3 PE=3 SV=2 CANONICAL=F6QW76-1" }, "locus": { "chromosome": "11", "start_pos": 16112640, "end_pos": 16072508, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000068365.3", "url": "https://www.ensembl.org/id/ENSBTAT00000068365.3" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000063477.2", "url": "https://www.ensembl.org/id/ENSBTAP00000063477.2" } ] } }, { "isoform_ac": "F6QW76-1", "url": "https://www.uniprot.org/uniprotkb/F6QW76/entry", "sequence": { "sequence": "MGSSGLGKAATLDELLSTCIEMFDDNGELNNSYLPRIVLLMHRWYLSSTELAEKLLCIYRNASGESCDEFRLKICYFMRYWIVKFPAEFNLDLGLIRMTEEFREVASQLGYEKHTSLIDISSIPSYDWMRRVTQRKKVSKKGKACLLFDHLEPIELAEHLTFLEHKSFRRISFTDYQSYVIHGCLENNPTLERSIALFNGISKWVQLMVLSKPTPQQRAEVITKFINVAKKLLQLKNFNTLMAVVGGLSHSSISRLKETHSHLSSEVTKNWNEMMELVSSNGNYCNYRKAFADCDGFKIPILGVHLKDLIAVHVIFPDWTEENKVNIVKMHQLSVTLSELVSLQNASHHLEPNLDLINLLTLSLDLYHTEDDIYKLSLVLEPRNSKSQPTSPTTPTKPVVPLEWASGVMPKPDPTVINKHIRKLVESVFRNYDHDHDGYISQEDFESIAANFPFLDSFCVLDKDQDGLISKDEMMAYFLRAKSQLHCKMGPGFVHNFQEMTYLKPTFCEHCAGFLWGIIKQGYKCKDCGANCHKQCKDLLVLACRRFARAPSLGSSHGSLPGSPSLPPVQDEVFEFPGVTAGHRDLDSRAITLVTGSSGKISVRLQRATTSQATQTEPVWSEAGWGDSGSHTFPKMRSKFHDKAAKDKGFAKWENEKPRVQAGVDVVDRGTTFEPDQDEADMDETKQDGEDG", "length": 692, "header": "tr|F6QW76-1|F6QW76_BOVIN Isoform 1 of RAS guanyl releasing protein 3 OS=Bos taurus OX=9913 GN=RASGRP3 PE=3 SV=1 CANONICAL=F6QW76-1" }, "locus": { "chromosome": "11", "start_pos": 16114201, "end_pos": 16072508, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000046852.6", "url": "https://www.ensembl.org/id/ENSBTAT00000046852.6" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000044100.4", "url": "https://www.ensembl.org/id/ENSBTAP00000044100.4" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [ { "id": "R-BTA-1169092", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-BTA-1169092", "resource": "Reactome", "description": "Activation of RAS in B cells" }, { "id": "R-BTA-5673001", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-BTA-5673001", "resource": "Reactome", "description": "RAF/MAP kinase cascade" } ], "orthologs": [ { "uniprot_canonical_ac": "A0A4X1T4J2-1", "protein_name": "RAS guanyl releasing protein 3", "gene_name": "RASGRP3", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MGSSGLGKAATLDELLSTCIEMFDDNGELNNSYLPRIVLLMHRWYLSSTELAGKLLCMYRNASGESCDEFRLKICYFMRYWILKFPAEFNLDLGLIHMTEEFREVASQLGYEKHVSLIDISSIPSYDWMRRVTQRKKVSKKGKACLLFDHLEPIELAEHLTFLEHKSFRRISFTDYQSYVIHGCLENNPTLERSIALFNGISKWVQLMVLSKPTPQQRAEVITKFINVAKKLLQLKNFNTLMAVVGGLSHSSISRLKETHSHLSSEVTKNWNEMTELVSSNGNYCNYRKAFADCDGFKIPILGVHLKDLIAVHVIFPDWTEENKVNIVKMHQLSVTLSELVSLQNASHHLEPNLDLINLLTLSLDLYHTEDDIYKLSLVLEPRNSKSQPTSPTTPTKPMVPLEWASGVLPKPDPTVINKHIRKLVESVFRNYDHDHDGYISQEDFESIAANFPFLDSFCVLDKDQDGLISKDEMMAYFLRAKSQLHCKMGPGFVHNFQEMTYLKPTFCEHCAGFLWGIIKQGYKCKDCGANCHKQCKDLLVLACRRFARATSVGSSHGSLPGSPSLPPVQDEVFEFPGVAAGHRDLDSRAITLVTGSSRKISVRLQRATTSQATQTEPVWSEAGWGDSGSHTFPKMKSKFHDKATKDKGFAKWENEKPRVQAGVDVVDRGTAFELDQEEADMGETRQDGEDG", "length": 692 }, "evidence": [ { "id": "F6QW76", "url": "https://omabrowser.org/oma/group/F6QW76/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "A0A8M2B4V9-1", "protein_name": "Ras guanyl-releasing protein 3 isoform X1", "gene_name": "rasgrp3", "tax_id": 7955, "organism": "Danio rerio", "sequence": { "sequence": "MGSFTLGKAASLELLLDACIHAFDDKGELHENQLPRTFLLMHRWYVSSTELAGKLLIMYRDCRGDDCQRTRLKICYLMRYWIAEFPAEFDLDLGLIRLTEEFRDAAAELGGDKHIKLLDISTIPSYDWMRKLTQRKKQVKKGKASLLFDHLEPIELAEHLTFLEYKSIRRISFTDYQSYVIHGCLVDNPTLERSIALFNGISQWVQLMVLSKLTPQHRAEVITKYIHVAQKLLHLQNFNTLMAVVGGLSHSSISRLKETHSHLSPEVTKIWNEMTELVSSNGNYCAYRKAFGESKGFKIPILGVHLKDLIAVHVVFADWVEDGKVNITKMQQLFLTFNELVSLQSAVAQVEPNMDLIYLLNLSLDLYYTEDEIYELSLLREPRNPKSQPTSPTTPNKPLAPLDWASGVTTKPDPSVVNKHIRKVVDSVFRNYDHDHDGYISQEDFESIAANFPFLDSFCVLDKDQDGLISKDEMMAYFLRANPLLQCKMGPGFIHNFQEMTYLKPTFCEHCAGFLWGIIKQGYKCKDCGVNCHKQCRELLVLACRRLPRSTSLGSVSPGVLTHSSLPSSPNLPTCKDDDEVFTFPTVSPSSGSDLEGKSITLMTGSAQRISVRLQRATTSQATQTEEHLWPENGWAAVADSGSHTFPKMRYRPHRKASKSKGFARWENDTQGSMGTRNSRNSQEHSEESQQNGLTEQHTNKTRTSEIS", "length": 708 }, "evidence": [ { "id": "F6QW76", "url": "https://omabrowser.org/oma/group/F6QW76/", "database": "OMA" } ], "glygen_name": "Zebrafish", "common_name": "Zebrafish" }, { "uniprot_canonical_ac": "Q8IV61-1", "protein_name": "Ras guanyl-releasing protein 3", "gene_name": "RASGRP3", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MGSSGLGKAATLDELLCTCIEMFDDNGELDNSYLPRIVLLMHRWYLSSTELAEKLLCMYRNATGESCNEFRLKICYFMRYWILKFPAEFNLDLGLIRMTEEFREVASQLGYEKHVSLIDISSIPSYDWMRRVTQRKKVSKKGKACLLFDHLEPIELAEHLTFLEHKSFRRISFTDYQSYVIHGCLENNPTLERSIALFNGISKWVQLMVLSKPTPQQRAEVITKFINVAKKLLQLKNFNTLMAVVGGLSHSSISRLKETHSHLSSEVTKNWNEMTELVSSNGNYCNYRKAFADCDGFKIPILGVHLKDLIAVHVIFPDWTEENKVNIVKMHQLSVTLSELVSLQNASHHLEPNMDLINLLTLSLDLYHTEDDIYKLSLVLEPRNSKSQPTSPTTPNKPVVPLEWALGVMPKPDPTVINKHIRKLVESVFRNYDHDHDGYISQEDFESIAANFPFLDSFCVLDKDQDGLISKDEMMAYFLRAKSQLHCKMGPGFIHNFQEMTYLKPTFCEHCAGFLWGIIKQGYKCKDCGANCHKQCKDLLVLACRRFARAPSLSSGHGSLPGSPSLPPAQDEVFEFPGVTAGHRDLDSRAITLVTGSSRKISVRLQRATTSQATQTEPVWSEAGWGDSGSHTFPKMKSKFHDKAAKDKGFAKWENEKPRVHAGVDVVDRGTEFELDQDEGEETRQDGEDG", "length": 690 }, "evidence": [ { "id": "F6QW76", "url": "https://omabrowser.org/oma/group/F6QW76/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" } ], "go_annotation": { "categories": [ { "name": "Molecular Function", "total": 6, "go_terms": [ { "name": "GTPase activator activity", "id": "GO:0005096", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005096", "evidence": [ { "database": "UniProtKB", "id": "F6QW76", "url": "https://www.uniprot.org/uniprotkb/F6QW76" } ], "pmid": "" }, { "name": "zinc ion binding", "id": "GO:0008270", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008270", "evidence": [ { "database": "UniProtKB", "id": "F6QW76", "url": "https://www.uniprot.org/uniprotkb/F6QW76" } ], "pmid": "" }, { "name": "calcium ion binding", "id": "GO:0005509", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005509", "evidence": [ { "database": "UniProtKB", "id": "F6QW76", "url": "https://www.uniprot.org/uniprotkb/F6QW76" } ], "pmid": "" }, { "name": "kinase binding", "id": "GO:0019900", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0019900", "evidence": [ { "database": "UniProtKB", "id": "F6QW76", "url": 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"evidence": [ { "database": "UniProtKB", "id": "F6QW76", "url": "https://www.uniprot.org/uniprotkb/F6QW76" } ], "pmid": "" }, { "name": "plasma membrane", "id": "GO:0005886", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005886", "evidence": [ { "database": "UniProtKB", "id": "F6QW76", "url": "https://www.uniprot.org/uniprotkb/F6QW76" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 2, "go_terms": [ { "name": "small GTPase-mediated signal transduction", "id": "GO:0007264", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007264", "evidence": [ { "database": "UniProtKB", "id": "F6QW76", "url": "https://www.uniprot.org/uniprotkb/F6QW76" } ], "pmid": "" }, { "name": "Ras protein signal transduction", "id": "GO:0007265", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007265", "evidence": [ { "database": "UniProtKB", "id": "F6QW76", "url": "https://www.uniprot.org/uniprotkb/F6QW76" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 30, "end_pos": 32, "annotation": "n_glycosylation_sequon" }, { "start_pos": 345, "end_pos": 347, "annotation": "n_glycosylation_sequon" }, { "start_pos": 61, "end_pos": 63, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "F6QW76", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F6QW76" }, { "id": "PS50222", "database": "PROSITE", "url": "https://prosite.expasy.org/PS50222" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "EF-hand", "eco_id": "ECO_0000259", "start_pos": 420, "end_pos": 455, "start_aa": "His", "end_aa": "Leu", "glycosite_overlap": [] }, { "evidence": [ { "id": "F6QW76", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F6QW76" }, { "id": "PS50212", "database": "PROSITE", "url": "https://prosite.expasy.org/PS50212" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "N-terminal Ras-GEF", "eco_id": "ECO_0000259", "start_pos": 3, "end_pos": 125, "start_aa": "Ser", "end_aa": "Ser", "glycosite_overlap": [] }, { "evidence": [ { "id": "F6QW76", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F6QW76" }, { "id": "PS50081", "database": "PROSITE", "url": "https://prosite.expasy.org/PS50081" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "Phorbol-ester/DAG-type", "eco_id": "ECO_0000259", "start_pos": 494, "end_pos": 544, "start_aa": "Val", "end_aa": "Cys", "glycosite_overlap": [] }, { "evidence": [ { "id": "F6QW76", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F6QW76" }, { "id": "PS50009", "database": "PROSITE", "url": "https://prosite.expasy.org/PS50009" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "Ras-GEF", "eco_id": "ECO_0000259", "start_pos": 152, "end_pos": 383, "start_aa": "Glu", "end_aa": "Arg", "glycosite_overlap": [] } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" }, { "name": "homologset.oma", "label": "OMA Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 30, "end_pos": 32 }, { "start_pos": 345, "end_pos": 347 }, { "start_pos": 61, "end_pos": 63 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", 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"ENSBTAP00000020131.4", "url": "https://www.ensembl.org/id/ENSBTAP00000020131.4" } ] } } ], "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "other", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 73, "start_aa": "Thr", "end_pos": 73, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr73", "evidence": [ { "id": "", "database": "GlyGen", "url": "https://data.glygen.org/" } ], "filter_code": "000000000000000010000.00000000001000.0.01000" } ], "phosphorylation": [], "glycation": [], "keywords": [ "glycoprotein", "glycoprotein_predicted" ], "publication": [], "pathway": [], "orthologs": [], "go_annotation": {}, "pro_annotation": [], "site_annotation": [], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], 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{ "id": "F6R112", "url": "https://alphafold.ebi.ac.uk/entry/F6R112", "database": "AlphaFoldDB", "categories": [] }, { "id": "IPR003309", "url": "https://www.ebi.ac.uk/interpro/entry/IPR003309", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR013087", "url": "https://www.ebi.ac.uk/interpro/entry/IPR013087", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR036236", "url": "https://www.ebi.ac.uk/interpro/entry/IPR036236", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR038269", "url": "https://www.ebi.ac.uk/interpro/entry/IPR038269", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR050589", "url": "https://www.ebi.ac.uk/interpro/entry/IPR050589", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "PTHR24404", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR24404", "database": "PANTHER", "categories": [ "Protein 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"strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000001821.6", "url": "https://www.ensembl.org/id/ENSBTAT00000001821.6" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000001821.5", "url": "https://www.ensembl.org/id/ENSBTAP00000001821.5" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [], "orthologs": [], "go_annotation": { "categories": [ { "name": "Molecular Function", "total": 2, "go_terms": [ { "name": "DNA binding", "id": "GO:0003677", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003677", "evidence": [ { "database": "UniProtKB", "id": "F6R112", "url": "https://www.uniprot.org/uniprotkb/F6R112" } ], "pmid": "" }, { "name": "zinc ion binding", "id": "GO:0008270", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008270", "evidence": [ { "database": "UniProtKB", "id": "F6R112", "url": "https://www.uniprot.org/uniprotkb/F6R112" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 1, "go_terms": [ { "name": "nucleus", "id": "GO:0005634", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005634", "evidence": [ { "database": "UniProtKB", "id": "F6R112", "url": "https://www.uniprot.org/uniprotkb/F6R112" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 3, "go_terms": [ { "name": "DNA-templated transcription", "id": "GO:0006351", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006351", "evidence": [ { "database": "UniProtKB", "id": "F6R112", "url": "https://www.uniprot.org/uniprotkb/F6R112" } ], "pmid": "" }, { "name": "spermatogenesis", "id": "GO:0007283", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007283", "evidence": [ { "database": "UniProtKB", "id": "F6R112", "url": "https://www.uniprot.org/uniprotkb/F6R112" } ], "pmid": "" }, { "name": "cell differentiation", "id": "GO:0030154", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030154", "evidence": [ { "database": "UniProtKB", "id": "F6R112", "url": 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"database": "AlphaFoldDB", "categories": [] }, { "id": "ENSBTAG00000026172", "url": "https://bgee.org/?page=gene&gene_id=ENSBTAG00000026172", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "540325", "url": "https://www.ncbi.nlm.nih.gov/gene/540325", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR007053", "url": "https://www.ebi.ac.uk/interpro/entry/IPR007053", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR043299", "url": "https://www.ebi.ac.uk/interpro/entry/IPR043299", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "bta:540325", "url": "https://www.genome.jp/dbget-bin/www_bget?bta:540325", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "MGNQMDK", "url": "https://omabrowser.org/oma/group/MGNQMDK/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "F6R1D7", "url": "https://www.orthodb.org/?gene=F6R1D7", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR46341", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR46341", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR46341:SF2", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR46341:SF2", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF04970", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF04970", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "NP_001099102", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001099102", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "F6R1D7", "url": "https://www.uniprot.org/uniprotkb/F6R1D7", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "F6R1D7-1", "url": "https://www.uniprot.org/uniprotkb/F6R1D7-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MGNQVEKLTHLSYKEVPTADPTGVDRDDGPRIGVSYIFSNDDEDMEPQQPPQGPDGGGGGLPDGGDGPSLPPPQPYDPRLHEVECSVFYRDECIYQKSFSPGSAALSTYTPENLLNKCRPGDLVEFVSQAQYPHWAVYVGNFQVVHLHRLEVSNSFLTDASQGRRGRVVNDLYRYKPLSPSAVVRNALAHVGAKERELSWRNSESFAAWCRYGKREFKIGGELRIGKQPYRLQIQLSAQRSHTLEFQSLEDLIMEKRRNDQIGRTAVLQELATHLHPVEPDEGDSDATRTTPPPGRLPAPGREEEENRETVVH", "length": 313, "header": "tr|F6R1D7-1|F6R1D7_BOVIN Isoform 1 of LRAT domain containing 2 OS=Bos taurus OX=9913 GN=LRATD2 PE=3 SV=1 CANONICAL=F6R1D7-1" }, "isoforms": [ { "isoform_ac": "F6R1D7-1", "url": "https://www.uniprot.org/uniprotkb/F6R1D7/entry", "sequence": { "sequence": "MGNQVEKLTHLSYKEVPTADPTGVDRDDGPRIGVSYIFSNDDEDMEPQQPPQGPDGGGGGLPDGGDGPSLPPPQPYDPRLHEVECSVFYRDECIYQKSFSPGSAALSTYTPENLLNKCRPGDLVEFVSQAQYPHWAVYVGNFQVVHLHRLEVSNSFLTDASQGRRGRVVNDLYRYKPLSPSAVVRNALAHVGAKERELSWRNSESFAAWCRYGKREFKIGGELRIGKQPYRLQIQLSAQRSHTLEFQSLEDLIMEKRRNDQIGRTAVLQELATHLHPVEPDEGDSDATRTTPPPGRLPAPGREEEENRETVVH", "length": 313, "header": "tr|F6R1D7-1|F6R1D7_BOVIN Isoform 1 of LRAT domain containing 2 OS=Bos taurus OX=9913 GN=LRATD2 PE=3 SV=1 CANONICAL=F6R1D7-1" }, "locus": { "chromosome": "14", "start_pos": 13922435, "end_pos": 13921497, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000037080.6", "url": "https://www.ensembl.org/id/ENSBTAT00000037080.6" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000044908.4", "url": "https://www.ensembl.org/id/ENSBTAP00000044908.4" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [ { "id": "bta:540325", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?bta:540325", "resource": "KEGG Pathway" } ], "orthologs": [ { "uniprot_canonical_ac": "A0A8V0Y2K7-1", "protein_name": "LRAT domain containing 2", "gene_name": "FAM84B", "tax_id": 9031, "organism": "Gallus gallus", "sequence": { "sequence": "MGNQVEKLTHLNYKEVPTADPTGMDRDEGPRIGVSYIFSNDDDELEQQQDSGHDLGGEHPALQPYDPQLHEVECSVYYRDECIYQKSFSEEDVLPEEGEEGGRGHLSTYTPENLLNRCKPGDLVEFVCQAQYPHWVVYVGDFQVVHLHRLEVVNSFLTDASQGRRGRIANQLYRYKPLSPAAVVRNALEQVGCKDRDLSWRNSECFAAWCRYGKREFKIGGELRIGKQPYRLQIRLGDKRSHTLEFQSLEDLIMEKRRNDQIGRAAVIQELSSHLQAAEEEDEEEEEDHPHHPGARTAVE", "length": 300 }, "evidence": [ { "id": "F6R1D7", "url": "https://omabrowser.org/oma/group/F6R1D7/", "database": "OMA" } ], "glygen_name": "Chicken", "common_name": "Chicken" }, { "uniprot_canonical_ac": "D3YXJ5-1", "protein_name": "LRAT domain containing 1", "gene_name": "Lratd2", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MGNQVEKLTHLSYKEVPTADPTGVDRDDGPRIGVSYIFSNDDEDVEPQPPPQGLDGGALSDSGDRPPLPPPQPYDPRQHEVECSVFYRDECIYQKSFAPGSAALSTYTPENLLNKCSPGDLVEFVSQAQYPHWAVYVGNFQVVHLHRLEVSNSFLTDASQGRRGRVVNDLYRYKPLSPSAVVRNALAHVGAKERELSWRNSESFAAWCRYGKREFKIGGELRIGKQPYRLQIQLSAQRSHTLEFQSLEDLIMEKRRNDQIGRAAVLQELATHLHPAEPDEGDSDATRTTPSPLRPPASGSEEENGDSVVH", "length": 310 }, "evidence": [ { "id": "F6R1D7", "url": "https://omabrowser.org/oma/group/F6R1D7/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "D3ZV96-1", "protein_name": "LRAT domain containing 2", "gene_name": "Lratd2", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MGNQVEKLTHLSYKEVPTADPTGVDRDDGPRIGVSYIFSNDDEDVEPQPPPQGLDGGALSDSGDRPSLPPPQPYDPRQHEVECSVFYRDECIYQKSFAPGSAALSTYTPENLLNKCSPGDLVEFVSQAQYPHWAVYVGNFQVVHLHRLEVSNSFLTDASQGRRGRVVNDLYRYKPLSPSAVVRNALAHVGAKERELSWRNSESFAAWCRYGKREFKIGGELRIGKQPYRLQIQLSAQRSHTLEFQSLEDLIMEKRRNDQIGRAAVLQELATHLHPAEPDEGDSDAARTTPSPLRPPALGSEEENGESAVH", "length": 310 }, "evidence": [ { "id": "F6R1D7", "url": "https://omabrowser.org/oma/group/F6R1D7/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "Q96KN1-1", "protein_name": "Protein LRATD2", "gene_name": "LRATD2", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MGNQVEKLTHLSYKEVPTADPTGVDRDDGPRIGVSYIFSNDDEDVEPQPPPQGPDGGGLPDGGDGPPPPQPQPYDPRLHEVECSVFYRDECIYQKSFAPGSAALSTYTPENLLNKCKPGDLVEFVSQAQYPHWAVYVGNFQVVHLHRLEVINSFLTDASQGRRGRVVNDLYRYKPLSSSAVVRNALAHVGAKERELSWRNSESFAAWCRYGKREFKIGGELRIGKQPYRLQIQLSAQRSHTLEFQSLEDLIMEKRRNDQIGRAAVLQELATHLHPAEPEEGDSNVARTTPPPGRPPAPSSEEEDGEAVAH", "length": 310 }, "evidence": [ { "id": "F6R1D7", "url": "https://omabrowser.org/oma/group/F6R1D7/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" } ], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 2, "go_terms": [ { "name": "cytoplasm", "id": "GO:0005737", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005737", "evidence": [ { "database": "UniProtKB", "id": "F6R1D7", "url": "https://www.uniprot.org/uniprotkb/F6R1D7" } ], "pmid": "" }, { "name": "plasma membrane", "id": "GO:0005886", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005886", "evidence": [ { "database": "UniProtKB", "id": "F6R1D7", "url": "https://www.uniprot.org/uniprotkb/F6R1D7" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [ { "pdb_id": "AF-F6R1D7-F1", "pdb_chain": "global", "start_pos": 1, "end_pos": 313, "overlap": "1.0", "method": "AlphaFold", "type": "alphafold", "resolution": -1.0, "url": "https://data.glygen.org/ln2downloads/pdb/current/AF-F6R1D7-F1.pdb", "url_external": "https://alphafold.ebi.ac.uk/entry/F6R1D7" } ], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "F6R1D7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F6R1D7" }, { "id": "PS51934", "database": "PROSITE", "url": "https://prosite.expasy.org/PS51934" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "LRAT", "eco_id": "ECO_0000259", "start_pos": 124, "end_pos": 219, "start_aa": "Val", "end_aa": "Ile", "glycosite_overlap": [] } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "homologset.oma", "label": "OMA Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": 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{ "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ], "tool_support": { "graph_view": "yes" } }, { "uniprot_canonical_ac": "F6R1P1-1", "uniprot_ac": "F6R1P1", "uniprot_id": "F6R1P1_BOVIN", "mass": { "chemical_mass": 46193.0, "monoisotopic_mass": 46193.0 }, "refseq": {}, "gene_names": [ { "name": "TOR3A", "type": "recommended", "evidence": [ { "id": "F6R1P1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F6R1P1" } ] } ], "protein_names": [ { "name": "Torsin-3A", "type": "recommended", "evidence": [ { "id": "F6R1P1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F6R1P1/entry#names_and_taxonomy" } ] }, { "name": "Torsin family 3 member A", "type": "synonym", "evidence": [ { "id": "F6R1P1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F6R1P1/entry#names_and_taxonomy" } ] } ], "function": [], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Bos taurus", "taxid": 9913, "evidence": [ { "database": "UniProtKB", "id": "F6R1P1", "url": "https://www.uniprot.org/uniprotkb/F6R1P1" } ], "common_name": "Bovine", "glygen_name": "Bovine", "reference_species": "Bos taurus [9913]" } ], "gene": [ { "name": "TOR3A", "url": "https://www.uniprot.org/uniprotkb/F6R1P1", "locus": { "chromosome": "16", "start_pos": 60450960, "end_pos": 60422940, "strand": "-", "evidence": [ { "database": "Ensembl Gene", "id": "ENSBTAG00000014006", "url": "https://www.ensembl.org/id/ENSBTAG00000014006" } ] } } ], "crossref": [ { "id": "F6R1P1", "url": "https://alphafold.ebi.ac.uk/entry/F6R1P1", "database": "AlphaFoldDB", "categories": [] }, { "id": "IPR001270", "url": "https://www.ebi.ac.uk/interpro/entry/IPR001270", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR003593", "url": "https://www.ebi.ac.uk/interpro/entry/IPR003593", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR010448", "url": "https://www.ebi.ac.uk/interpro/entry/IPR010448", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR027417", "url": "https://www.ebi.ac.uk/interpro/entry/IPR027417", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR049337", "url": "https://www.ebi.ac.uk/interpro/entry/IPR049337", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "PTHR10760", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR10760", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR10760:SF3", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR10760:SF3", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF06309", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF06309", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF21376", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF21376", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "F6R1P1", "url": "https://www.uniprot.org/uniprotkb/F6R1P1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "F6R1P1-1", "url": "https://www.uniprot.org/uniprotkb/F6R1P1-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": 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"categories": [ "Protein Classification" ] }, { "id": "PTHR23288:SF15", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR23288:SF15", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF07303", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF07303", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "NP_001069854", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001069854", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "F6RA30", "url": "https://www.uniprot.org/uniprotkb/F6RA30", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "F6RA30-1", "url": "https://www.uniprot.org/uniprotkb/F6RA30-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MPTREPPRTHGSRGNLQTRPPGPGPPRLVSRGLKPSAPPTVYQPQPGAHRTKPKKIVFEDELPSRALLGTKKSTRAICERHVPRPHPVPDYELKYPPVSTAKDRSRYAAVFQDQYPEFLELQQEVGSAQAKLQQLEALLNSLPRPRSQKEAHVAARVWREFEKKQMDPSFLDKQARCHYLKGKLRHLKTQIQKFDDQGDSEGSVYF", "length": 206, "header": "tr|F6RA30-1|F6RA30_BOVIN Isoform 1 of Occludin/ELL domain containing 1 OS=Bos taurus OX=9913 GN=OCEL1 PE=3 SV=1 CANONICAL=F6RA30-1" }, "isoforms": [ { "isoform_ac": "F6RA30-1", "url": "https://www.uniprot.org/uniprotkb/F6RA30/entry", "sequence": { "sequence": "MPTREPPRTHGSRGNLQTRPPGPGPPRLVSRGLKPSAPPTVYQPQPGAHRTKPKKIVFEDELPSRALLGTKKSTRAICERHVPRPHPVPDYELKYPPVSTAKDRSRYAAVFQDQYPEFLELQQEVGSAQAKLQQLEALLNSLPRPRSQKEAHVAARVWREFEKKQMDPSFLDKQARCHYLKGKLRHLKTQIQKFDDQGDSEGSVYF", "length": 206, "header": "tr|F6RA30-1|F6RA30_BOVIN Isoform 1 of Occludin/ELL domain containing 1 OS=Bos taurus OX=9913 GN=OCEL1 PE=3 SV=1 CANONICAL=F6RA30-1" }, "locus": { "chromosome": "7", "start_pos": 5874368, "end_pos": 5872777, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000047416.3", "url": "https://www.ensembl.org/id/ENSBTAT00000047416.3" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000044623.2", "url": "https://www.ensembl.org/id/ENSBTAP00000044623.2" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [ { "id": "bta:615639", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?bta:615639", "resource": "KEGG Pathway" } ], "orthologs": [ { "uniprot_canonical_ac": "Q8VCR9-1", "protein_name": "Occludin/ELL domain-containing protein 1", "gene_name": "Ocel1", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MQIHAGPASRRGRRGPLARLSGPEATCNSRPAARGRQRAAAPRMPAPERPRSRRPQSQPGPGELCVKPRKIVFADELRPREPLHPEKHPRDLGPRLNPVPDYELKYPPVTNRRDRSRYAAVFQDQYGEFSELQREVGATQAKLQQLEALLLSLPPPRSQKEARMAAHVRREFEKKRVDPGFLDKQARCNYLKGKLRHLKAQIRKFDDQQDSNSEDSVYF", "length": 219 }, "evidence": [ { "id": "F6RA30", "url": "https://omabrowser.org/oma/group/F6RA30/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q9H607-1", "protein_name": "Occludin/ELL domain-containing protein 1", "gene_name": "OCEL1", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MHNPDGSASPTADPGSELQTLGQAARRPPPPRAGHDAPRRTRPSARKPLSCFSRRPMPTREPPKTRGSRGHLHTHPPGPGPPLQGLAPRGLKTSAPRPPCQPQPGPHKAKTKKIVFEDELLSQALLGAKKPIGAIPKGHKPRPHPVPDYELKYPPVSSERERSRYVAVFQDQYGEFLELQHEVGCAQAKLRQLEALLSSLPPPQSQKEAQVAARVWREFEMKRMDPGFLDKQARCHYLKGKLRHLKTQIQKFDDQGDSEGSVYF", "length": 264 }, "evidence": [ { "id": "F6RA30", "url": "https://omabrowser.org/oma/group/F6RA30/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" } ], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 3, "go_terms": [ { "name": "bicellular tight junction", "id": "GO:0005923", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005923", "evidence": [ { "database": "UniProtKB", "id": "F6RA30", "url": "https://www.uniprot.org/uniprotkb/F6RA30" } ], "pmid": "" }, { "name": "apical plasma membrane", "id": "GO:0016324", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016324", "evidence": [ { "database": "UniProtKB", "id": "F6RA30", "url": "https://www.uniprot.org/uniprotkb/F6RA30" } ], "pmid": "" }, { "name": "cytoplasmic vesicle", "id": "GO:0031410", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0031410", "evidence": [ { "database": "UniProtKB", "id": "F6RA30", "url": "https://www.uniprot.org/uniprotkb/F6RA30" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 1, "go_terms": [ { "name": "bicellular tight junction assembly", "id": "GO:0070830", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0070830", "evidence": [ { "database": "UniProtKB", "id": "F6RA30", "url": "https://www.uniprot.org/uniprotkb/F6RA30" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [ { "pdb_id": "AF-F6RA30-F1", "pdb_chain": "global", "start_pos": 1, "end_pos": 206, "overlap": "1.0", "method": "AlphaFold", "type": "alphafold", "resolution": -1.0, "url": "https://data.glygen.org/ln2downloads/pdb/current/AF-F6RA30-F1.pdb", "url_external": "https://alphafold.ebi.ac.uk/entry/F6RA30" } ], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "F6RA30", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F6RA30" }, { "id": "PS51980", "database": "PROSITE", "url": "https://prosite.expasy.org/PS51980" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "OCEL", "eco_id": "ECO_0000259", "start_pos": 89, "end_pos": 199, "start_aa": "Pro", "end_aa": "Asp", "glycosite_overlap": [] } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "homologset.oma", "label": "OMA Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ], "tool_support": { "graph_view": "yes" } }, { "uniprot_canonical_ac": "F6RA71-1", "uniprot_ac": "F6RA71", "uniprot_id": "F6RA71_BOVIN", "mass": { "chemical_mass": 56657.0, "monoisotopic_mass": 56657.0 }, "refseq": {}, "gene_names": [ { "name": "VAT1L", "type": "recommended", "evidence": [ { "id": "F6RA71", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F6RA71" } ] } ], "protein_names": [ { "name": "NADPH:quinone reductase", "type": "recommended", "evidence": [ { "id": "F6RA71", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F6RA71/entry#names_and_taxonomy" } ] }, { "name": "1.6.5.5", "type": "synonym", "evidence": [ { "id": "F6RA71", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F6RA71/entry#names_and_taxonomy" } ] } ], "function": [], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Bos taurus", "taxid": 9913, "evidence": [ { "database": "UniProtKB", "id": "F6RA71", "url": "https://www.uniprot.org/uniprotkb/F6RA71" } ], "common_name": "Bovine", "glygen_name": "Bovine", "reference_species": "Bos taurus [9913]" } ], "gene": [ { "name": "VAT1L", "url": "https://www.uniprot.org/uniprotkb/F6RA71", "locus": { "chromosome": "18", "start_pos": 5169822, "end_pos": 5003977, "strand": "-", "evidence": [ { "database": "Ensembl Gene", "id": "ENSBTAG00000018146", "url": "https://www.ensembl.org/id/ENSBTAG00000018146" } ] } } ], "crossref": [ { "id": "F6RA71", "url": "https://alphafold.ebi.ac.uk/entry/F6RA71", "database": "AlphaFoldDB", "categories": [] }, { "id": "cd08275", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd08275", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "IPR002364", "url": "https://www.ebi.ac.uk/interpro/entry/IPR002364", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR011032", "url": "https://www.ebi.ac.uk/interpro/entry/IPR011032", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR013154", "url": "https://www.ebi.ac.uk/interpro/entry/IPR013154", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR020843", "url": "https://www.ebi.ac.uk/interpro/entry/IPR020843", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR036291", "url": "https://www.ebi.ac.uk/interpro/entry/IPR036291", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR052100", "url": "https://www.ebi.ac.uk/interpro/entry/IPR052100", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "PTHR44054", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR44054", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR44054:SF2", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR44054:SF2", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF08240", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF08240", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF13602", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF13602", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "14269", "url": "https://www.rhea-db.org/rhea/14269", "database": "Rhea", "categories": [ "Enzyme and Pathway" ] }, { "id": "F6RA71", "url": "https://www.uniprot.org/uniprotkb/F6RA71", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "F6RA71-1", "url": "https://www.uniprot.org/uniprotkb/F6RA71-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MSFFQKGSLTEDKKPELGVKLAEKRELRLCSGRTERRAVRQGARLFGGLRRSPWTAALLAEAAAIAPPSIPHSTGGTRERGSPSPPAPQQPQPVRPAPPRAMAKEGVEKAEETEQMIEKEAGKEPAEGGGGGGSHRLGDAQEMRAVVLAGFGGLNKLRVTRKAMPEPQDGELKIRVKACGLNFIDLMVRQGNIDTPPKTPLVPGFECSGIVEALGDSVKGFEIGDRVMAFVNYSAWAEVVCTPVEFVYKIPEDMSFSEAAAFPMNFVTAYMMLFEVANLREGMSVLIHSAGGGVGQAVAQLCSTVPNVTVFGTASTFKHEAIKDSVTHLFDRNADYVQEVKRISAEGVDIVLDCLCGDNTGKGLSLLKPLGTYILYGSSNMVTGETKSFFSFAKSWWQVEKVNPIKLYEENKVIAGFSLLNLLFKQGRAGLIRGVVDKLIALYNQKKIKPVVDSLWALEEVKEAMQRIHDRGNIGKLILDVEKTPTPLMANDSTETSEAGEEEEDHEGDSENKERMPFIQ", "length": 520, "header": "tr|F6RA71-1|F6RA71_BOVIN Isoform 1 of NADPH:quinone reductase OS=Bos taurus OX=9913 GN=VAT1L PE=3 SV=1 CANONICAL=F6RA71-1" }, "isoforms": [ { "isoform_ac": "F6RA71-1", "url": "https://www.uniprot.org/uniprotkb/F6RA71/entry", "sequence": { "sequence": "MSFFQKGSLTEDKKPELGVKLAEKRELRLCSGRTERRAVRQGARLFGGLRRSPWTAALLAEAAAIAPPSIPHSTGGTRERGSPSPPAPQQPQPVRPAPPRAMAKEGVEKAEETEQMIEKEAGKEPAEGGGGGGSHRLGDAQEMRAVVLAGFGGLNKLRVTRKAMPEPQDGELKIRVKACGLNFIDLMVRQGNIDTPPKTPLVPGFECSGIVEALGDSVKGFEIGDRVMAFVNYSAWAEVVCTPVEFVYKIPEDMSFSEAAAFPMNFVTAYMMLFEVANLREGMSVLIHSAGGGVGQAVAQLCSTVPNVTVFGTASTFKHEAIKDSVTHLFDRNADYVQEVKRISAEGVDIVLDCLCGDNTGKGLSLLKPLGTYILYGSSNMVTGETKSFFSFAKSWWQVEKVNPIKLYEENKVIAGFSLLNLLFKQGRAGLIRGVVDKLIALYNQKKIKPVVDSLWALEEVKEAMQRIHDRGNIGKLILDVEKTPTPLMANDSTETSEAGEEEEDHEGDSENKERMPFIQ", "length": 520, "header": "tr|F6RA71-1|F6RA71_BOVIN Isoform 1 of NADPH:quinone reductase OS=Bos taurus OX=9913 GN=VAT1L PE=3 SV=1 CANONICAL=F6RA71-1" }, "locus": { "chromosome": "18", "start_pos": 5168715, "end_pos": 5004122, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000024154.7", "url": "https://www.ensembl.org/id/ENSBTAT00000024154.7" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000024154.5", "url": "https://www.ensembl.org/id/ENSBTAP00000024154.5" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [ "enzyme" ], "publication": [], "pathway": [], "orthologs": [], "go_annotation": { "categories": [ { "name": "Molecular Function", "total": 2, "go_terms": [ { "name": "zinc ion binding", "id": "GO:0008270", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008270", "evidence": [ { "database": "UniProtKB", "id": "F6RA71", "url": "https://www.uniprot.org/uniprotkb/F6RA71" } ], "pmid": "" }, { "name": "oxidoreductase activity", "id": "GO:0016491", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016491", "evidence": [ { "database": "UniProtKB", "id": "F6RA71", "url": "https://www.uniprot.org/uniprotkb/F6RA71" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 232, "end_pos": 234, "annotation": "n_glycosylation_sequon" }, { "start_pos": 307, "end_pos": 309, "annotation": "n_glycosylation_sequon" }, { "start_pos": 491, "end_pos": 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"MEAPLVSLDEEFEDLRPCCSEDPEEKPRCFYGSSPHHLEDPSLSELENFSSEIISFKSMEDLVNEFDEKLNVCFRNYNAKTENLAPVKNQFQIQEEEETLQDEEVWDALTDNYIPSLSEDWRDPNMEALNGNNSDTEIHEKEEEEFNEKSEHDSGITEEPLLTADQVIEEIEEMMQNSPDPEEEEEVLEEEDGGETSSQADSVLLQEMQALTQTFNNNWSYEGPSGPREPLPWAGGSDPAGWSSPAGLRHMSGSELMELLDQVEGAIRDFSEELVQQLARRDELEFEKEVKNSFITVLIEVQNKQKEQRELMKKRRKEKGLSLQSSRIDKGSQMPLKRFSMEGISNILQSGIRQTFGPSGSDKQYLNTVIPYEKKASPPSVEDLQMLTNILFAMKEDNEKVPTLLTDYILKVLCPT", "length": 416, "header": "tr|F6RC12-1|F6RC12_BOVIN Isoform 1 of Fasciculation and elongation protein zeta 1 OS=Bos taurus OX=9913 GN=FEZ1 PE=3 SV=1 CANONICAL=F6RC12-1" }, "isoforms": [ { "isoform_ac": "F6RC12-1", "url": "https://www.uniprot.org/uniprotkb/F6RC12/entry", "sequence": { "sequence": 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"total": 1, "go_terms": [ { "name": "gamma-tubulin binding", "id": "GO:0043015", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0043015", "evidence": [ { "database": "UniProtKB", "id": "F6RC12", "url": "https://www.uniprot.org/uniprotkb/F6RC12" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 132, "end_pos": 134, "annotation": "n_glycosylation_sequon" }, { "start_pos": 218, "end_pos": 220, "annotation": "n_glycosylation_sequon" }, { "start_pos": 48, "end_pos": 50, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 132, "end_pos": 134 }, { "start_pos": 218, "end_pos": 220 }, { "start_pos": 48, "end_pos": 50 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", 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"sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ], "tool_support": { "graph_view": "yes" } }, { "uniprot_canonical_ac": "F6RC73-1", "uniprot_ac": "F6RC73", "uniprot_id": "F6RC73_BOVIN", "mass": { "chemical_mass": 32327.0, "monoisotopic_mass": 32327.0 }, "refseq": {}, "gene_names": [ { "name": "LYPLAL1", "type": "recommended", "evidence": [ { "id": "F6RC73", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F6RC73" } ] } ], "protein_names": [ { "name": "Lysophospholipase-like protein 1", "type": "recommended", "evidence": [ { "id": "F6RC73", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F6RC73/entry#names_and_taxonomy" } ] }, { "name": "3.1.2.22", "type": "synonym", "evidence": [ { "id": "F6RC73", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F6RC73/entry#names_and_taxonomy" } ] } ], "function": [ { "annotation": "Palmitoyl thioesterase that catalyzes depalmitoylation of CGAS and KCNMA1. Acts as a regulator of innate immunity by mediating depalmitoylation of CGAS, thereby preventing CGAS homodimerization and cyclic GMP-AMP synthase activity. Does not exhibit phospholipase nor triacylglycerol lipase activity, able to hydrolyze only short chain substrates due to its shallow active site.", "evidence": [ { "database": "UniProtKB", "id": "F6RC73", "url": "https://www.uniprot.org/uniprotkb/F6RC73#function" }, { "database": "UniProtKB", "id": "ARBA00057451", "url": "https://www.uniprot.org/uniprotkb/ARBA00057451#function" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Bos taurus", "taxid": 9913, "evidence": [ { "database": "UniProtKB", "id": "F6RC73", "url": "https://www.uniprot.org/uniprotkb/F6RC73" } ], "common_name": "Bovine", "glygen_name": "Bovine", "reference_species": "Bos taurus [9913]" } ], "gene": [ { "name": "LYPLAL1", "url": "https://www.uniprot.org/uniprotkb/F6RC73", "locus": { "chromosome": "16", "start_pos": 22690679, "end_pos": 22658281, "strand": "-", "evidence": [ { "database": "Ensembl Gene", "id": "ENSBTAG00000015534", "url": "https://www.ensembl.org/id/ENSBTAG00000015534" } ] } } ], "crossref": [ { "id": "F6RC73", "url": "https://alphafold.ebi.ac.uk/entry/F6RC73", "database": "AlphaFoldDB", "categories": [] }, { "id": "IPR003140", "url": "https://www.ebi.ac.uk/interpro/entry/IPR003140", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR029058", "url": "https://www.ebi.ac.uk/interpro/entry/IPR029058", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR050565", "url": "https://www.ebi.ac.uk/interpro/entry/IPR050565", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "PTHR10655", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR10655", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR10655:SF17", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR10655:SF17", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF02230", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF02230", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "19233", "url": "https://www.rhea-db.org/rhea/19233", "database": "Rhea", "categories": [ "Enzyme and Pathway" ] }, { "id": "F6RC73", "url": "https://www.uniprot.org/uniprotkb/F6RC73", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "F6RC73-1", "url": "https://www.uniprot.org/uniprotkb/F6RC73-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MTPVLENPNPQYSLTGLRLHPGAGLRNPAAQARLQARPLRAYVRVPAGRRRGGARAALVQAAVMAAPSGSARLRRCMVSPAGRHSASLIFLHGSGDSGQGLRTWIKQVLNQDLTFQHIKVIYPTAPPRPYTPLRGGISNVWFDRLKISNDCPEHLESIDVMCQVLTDLIDDEVKTGIKKNRILVGGFSMGGCMAMHLAYRNHQDVAGVFALSSFLNKASAVYQALQKSDGVLPELFQCHGTADELVLHSWGEETNSMLKSLGVSTKFHSFPGVYHELSKAELEKLKSWILTKLPD", "length": 295, "header": "tr|F6RC73-1|F6RC73_BOVIN Isoform 1 of Lysophospholipase-like protein 1 OS=Bos taurus OX=9913 GN=LYPLAL1 PE=3 SV=1 CANONICAL=F6RC73-1" }, "isoforms": [ { "isoform_ac": "F6RC73-1", "url": "https://www.uniprot.org/uniprotkb/F6RC73/entry", "sequence": { "sequence": "MTPVLENPNPQYSLTGLRLHPGAGLRNPAAQARLQARPLRAYVRVPAGRRRGGARAALVQAAVMAAPSGSARLRRCMVSPAGRHSASLIFLHGSGDSGQGLRTWIKQVLNQDLTFQHIKVIYPTAPPRPYTPLRGGISNVWFDRLKISNDCPEHLESIDVMCQVLTDLIDDEVKTGIKKNRILVGGFSMGGCMAMHLAYRNHQDVAGVFALSSFLNKASAVYQALQKSDGVLPELFQCHGTADELVLHSWGEETNSMLKSLGVSTKFHSFPGVYHELSKAELEKLKSWILTKLPD", "length": 295, "header": "tr|F6RC73-1|F6RC73_BOVIN Isoform 1 of Lysophospholipase-like protein 1 OS=Bos taurus OX=9913 GN=LYPLAL1 PE=3 SV=1 CANONICAL=F6RC73-1" }, "locus": { "chromosome": "16", "start_pos": 22688850, "end_pos": 22658438, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000020640.7", "url": "https://www.ensembl.org/id/ENSBTAT00000020640.7" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000020640.5", "url": "https://www.ensembl.org/id/ENSBTAP00000020640.5" } ] } } ], "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "other", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 124, "start_aa": "Thr", "end_pos": 124, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr124", "evidence": [ { "id": "", "database": "GlyGen", "url": "https://data.glygen.org/" } ], "filter_code": "000000000000000010000.00000000001000.0.01000" } ], "phosphorylation": [], "glycation": [], "keywords": [ "enzyme", "glycoprotein", "glycoprotein_predicted" ], "publication": [], "pathway": [], "orthologs": [], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 1, "go_terms": [ { "name": "cytosol", "id": "GO:0005829", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005829", "evidence": [ { "database": "UniProtKB", "id": "F6RC73", "url": "https://www.uniprot.org/uniprotkb/F6RC73" } ], "pmid": "" } ] }, { "name": "Molecular Function", "total": 1, "go_terms": [ { "name": "palmitoyl-(protein) hydrolase activity", "id": "GO:0008474", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008474", "evidence": [ { "database": "UniProtKB", "id": "F6RC73", "url": "https://www.uniprot.org/uniprotkb/F6RC73" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 1, "go_terms": [ { "name": "negative regulation of cGAS/STING signaling pathway", "id": "GO:0160049", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0160049", "evidence": [ { "database": "UniProtKB", "id": "F6RC73", "url": "https://www.uniprot.org/uniprotkb/F6RC73" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [], "ptm_annotation": [], "interactions": [], "reactions": [ { "id": "19233", "name": "", "equation": "S-hexadecanoyl-L-cysteinyl-[protein] + H2O = L-cysteinyl-[protein] + hexadecanoate + H(+)", "summary": "", "cellular_location": "", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [ "A0AAA9T2L1-1", "A0AAA9SCF5-1", "A0AAA9SFH2-1", "A0A3Q1M5Z8-1", "G3MWX2-1", "A0AAF6YMI2-1", "A5PKD9-1", "P45478-1", "Q3MHR0-1", "Q1ZYR0-1", "Q5E9H9-1", "F1MNH5-1", "Q2HJ19-1", "A0AAA9S0E0-1", "F1MYM8-1", "F6RC73-1", "F1N587-1" ], "evidence": [ { "id": "19233", "database": "Rhea", "url": "https://www.rhea-db.org/rhea/19233" } ] } ], "reaction_participants": [], "reaction_enzymes": [ { "uniprot_ac": "A0A3Q1M5Z8", "gene_name": "LYPLA1", "activity": [ { "ec_number": "3.1.2.22", "activity": "S-hexadecanoyl-L-cysteinyl-[protein] + H2O = L-cysteinyl-[protein] + hexadecanoate + H(+).", "evidence": [ { "id": "A0A3Q1M5Z8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1M5Z8" } ] }, { "ec_number": "3.1.2.22", "activity": "", "evidence": [ { "id": "A0A3Q1M5Z8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1M5Z8" } ] } ] }, { "uniprot_ac": "A0AAA9S0E0", "gene_name": "LYPLA2", "activity": [ { 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"evidence": [ { "id": "A0AAA9SCF5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9SCF5" } ] }, { "ec_number": "3.1.2.22", "activity": "", "evidence": [ { "id": "A0AAA9SCF5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9SCF5" } ] } ] }, { "uniprot_ac": "A0AAA9SFH2", "gene_name": "DESI1", "activity": [ { "ec_number": "3.1.2.22", "activity": "S-hexadecanoyl-L-cysteinyl-[protein] + H2O = L-cysteinyl-[protein] + hexadecanoate + H(+).", "evidence": [ { "id": "A0AAA9SFH2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9SFH2" } ] }, { "ec_number": "3.1.2.22", "activity": "", "evidence": [ { "id": "A0AAA9SFH2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9SFH2" } ] } ] }, { "uniprot_ac": "A0AAA9T2L1", "gene_name": "ABHD17B", "activity": [ { "ec_number": "3.1.2.22", "activity": "S-hexadecanoyl-L-cysteinyl-[protein] + H2O = L-cysteinyl-[protein] + hexadecanoate + H(+).", "evidence": [ { 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"categories": [ "Protein" ] }, { "id": "F6RD06", "url": "https://www.uniprot.org/uniprotkb/F6RD06", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "F6RD06-1", "url": "https://www.uniprot.org/uniprotkb/F6RD06-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "NPGIMHFLFRLILFFYVWGIFTAQGQKAEETTEEVKIEVLHRPENCSKTSKKGDLLNAHYDGFLAKDGSKFYCSRTQNEGHPKWFVLGVGQVIKGLDIGMMDMCPGEKRKLIIPPSFAYGKEGYAEGKIPPDATLIFEIELYAVTKGPRSVETFKQIDTDNDRQLSKTEISHYLKKEFEKDEKPRDQSYQTAVLEDFFKKNDHDGDGFISSKEYNVYQHDEL", "length": 222, "header": "tr|F6RD06-1|F6RD06_BOVIN Isoform 1 of peptidylprolyl isomerase OS=Bos taurus OX=9913 GN=FKBP7 PE=4 SV=1 CANONICAL=F6RD06-1" }, "isoforms": [ { "isoform_ac": "A0AAA9U1N7-1", "url": "https://www.uniprot.org/uniprotkb/A0AAA9U1N7/entry", "sequence": { "sequence": "NPGIMHFLFRLILFFYVWGIFTAQGQKAEETTEEVKIEVLHRPENCSKTSKKGDLLNAHYDGFLAKDGSKFYCSRTQNEGHPKWFVLGVGQVIKGLDIGMMDMCPGEKRKLIIPPSFAYGKEGYDKSLPEKGI", "length": 133, "header": "tr|A0AAA9U1N7-1|A0AAA9U1N7_BOVIN Computationally mapped isoform of peptidylprolyl isomerase OS=Bos taurus OX=9913 GN=FKBP7 PE=4 SV=1 CANONICAL=F6RD06-1" }, "locus": { "chromosome": "2", "start_pos": 18426109, "end_pos": 18418764, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000100229.2", "url": "https://www.ensembl.org/id/ENSBTAT00000100229.2" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000103151.1", "url": "https://www.ensembl.org/id/ENSBTAP00000103151.1" } ] } }, { "isoform_ac": "F6RD06-1", "url": "https://www.uniprot.org/uniprotkb/F6RD06/entry", "sequence": { "sequence": "NPGIMHFLFRLILFFYVWGIFTAQGQKAEETTEEVKIEVLHRPENCSKTSKKGDLLNAHYDGFLAKDGSKFYCSRTQNEGHPKWFVLGVGQVIKGLDIGMMDMCPGEKRKLIIPPSFAYGKEGYAEGKIPPDATLIFEIELYAVTKGPRSVETFKQIDTDNDRQLSKTEISHYLKKEFEKDEKPRDQSYQTAVLEDFFKKNDHDGDGFISSKEYNVYQHDEL", "length": 222, "header": "tr|F6RD06-1|F6RD06_BOVIN Isoform 1 of peptidylprolyl isomerase OS=Bos taurus OX=9913 GN=FKBP7 PE=4 SV=1 CANONICAL=F6RD06-1" }, "locus": { "chromosome": "2", "start_pos": 18426242, "end_pos": 18418764, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000001452.7", "url": "https://www.ensembl.org/id/ENSBTAT00000001452.7" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000001452.5", "url": "https://www.ensembl.org/id/ENSBTAP00000001452.5" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [ "enzyme" ], "publication": [], "pathway": [], "orthologs": [], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 1, "go_terms": [ { "name": "endoplasmic reticulum", "id": "GO:0005783", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005783", "evidence": [ { "database": "UniProtKB", "id": "F6RD06", "url": "https://www.uniprot.org/uniprotkb/F6RD06" } ], "pmid": "" } ] }, { "name": "Molecular Function", "total": 2, "go_terms": [ { "name": "calcium ion binding", "id": "GO:0005509", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005509", "evidence": [ { "database": "UniProtKB", "id": "F6RD06", "url": "https://www.uniprot.org/uniprotkb/F6RD06" } ], "pmid": "" }, { "name": "peptidyl-prolyl cis-trans isomerase activity", "id": "GO:0003755", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003755", "evidence": [ { "database": "UniProtKB", "id": "F6RD06", "url": "https://www.uniprot.org/uniprotkb/F6RD06" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 45, "end_pos": 47, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [ { "id": "16237", "name": "", "equation": "[protein]-peptidylproline (omega=180) = [protein]-peptidylproline (omega=0)", "summary": "", "cellular_location": "", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [ "A0A3Q1M4A4-1", "P18203-1", "Q5BIN5-1", "A6QPY8-1", "F1N4S5-1", "F1N6W2-1", "G3X8B1-1", "A0A3Q1LI03-1", "A0AAA9TG77-1", "F1MNW5-1", "E1B9G4-1", "G3MXV0-1", "Q2KJC8-1", "A0AAF6YJC8-1", "A0AAF6YJR2-1", "P26882-1", "F6RD06-1", "Q32PA9-1", "Q0P5D0-1", "Q2KJ44-1", "Q2HJ89-1", "Q08E11-1", "Q9TRY0-1", "A0A3Q1LK42-1", "A4FV72-1", "P26884-1", "P30404-1", "P62935-1", "P68107-1", "Q29RZ2-1", "P80311-1", "A0AAA9RV00-1", "F1MU79-1", "A0A3Q1LJJ1-1", "Q5E992-1", "Q2YDL5-1", "A0AAA9U018-1", "A0ABI0NKM5-1", "A0ABI0NMT7-1", "A0A3Q1LSB7-1" ], "evidence": [ { "id": "16237", "database": "Rhea", "url": "https://www.rhea-db.org/rhea/16237" } ] } ], "reaction_participants": [], "reaction_enzymes": [ { "uniprot_ac": "A0A3Q1LI03", "gene_name": "FKBP11", "activity": [ { "ec_number": "5.2.1.8", "activity": "[protein]-peptidylproline (omega=180) = [protein]-peptidylproline (omega=0).", "evidence": [ { "id": "A0A3Q1LI03", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1LI03" } ] }, { "ec_number": "5.2.1.8", "activity": "", "evidence": [ { "id": "A0A3Q1LI03", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1LI03" } ] } ] }, { "uniprot_ac": "A0A3Q1LJJ1", "gene_name": "", "activity": [ { "ec_number": "5.2.1.8", "activity": "[protein]-peptidylproline (omega=180) = [protein]-peptidylproline (omega=0).", "evidence": [ { "id": "A0A3Q1LJJ1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1LJJ1" } ] }, { "ec_number": "5.2.1.8", "activity": "", "evidence": [ { "id": "A0A3Q1LJJ1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1LJJ1" } ] } ] }, { "uniprot_ac": "A0A3Q1LK42", "gene_name": "FKBP8", "activity": [ { "ec_number": "5.2.1.8", "activity": "[protein]-peptidylproline (omega=180) = [protein]-peptidylproline (omega=0).", "evidence": [ { "id": "A0A3Q1LK42", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1LK42" } ] }, { "ec_number": "5.2.1.8", "activity": "", "evidence": [ { "id": "A0A3Q1LK42", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1LK42" } ] } ] }, { "uniprot_ac": "A0A3Q1LSB7", "gene_name": "LOC786614", "activity": [ { "ec_number": "5.2.1.8", "activity": "[protein]-peptidylproline (omega=180) = [protein]-peptidylproline (omega=0).", "evidence": [ { "id": "A0A3Q1LSB7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1LSB7" } ] }, { "ec_number": "5.2.1.8", "activity": "", "evidence": [ { "id": "A0A3Q1LSB7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1LSB7" } ] } ] }, { "uniprot_ac": "A0A3Q1M4A4", "gene_name": "LOC112445968", "activity": [ { "ec_number": "5.2.1.8", "activity": "[protein]-peptidylproline (omega=180) = [protein]-peptidylproline (omega=0).", "evidence": [ { "id": "A0A3Q1M4A4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1M4A4" } ] }, { "ec_number": "5.2.1.8", "activity": "", "evidence": [ { "id": "A0A3Q1M4A4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1M4A4" } ] } ] }, { "uniprot_ac": "A0AAA9RV00", "gene_name": "PPIE", "activity": [ { "ec_number": "5.2.1.8", "activity": "[protein]-peptidylproline (omega=180) = [protein]-peptidylproline (omega=0).", "evidence": [ { "id": "A0AAA9RV00", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9RV00" } ] }, { "ec_number": "5.2.1.8", "activity": "", "evidence": [ { "id": "A0AAA9RV00", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9RV00" } ] } ] }, { "uniprot_ac": "A0AAA9TG77", "gene_name": "FKBP15", "activity": [ { "ec_number": "5.2.1.8", "activity": "[protein]-peptidylproline (omega=180) = [protein]-peptidylproline (omega=0).", "evidence": [ { "id": "A0AAA9TG77", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TG77" } ] }, { "ec_number": "5.2.1.8", "activity": "", "evidence": [ { "id": "A0AAA9TG77", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TG77" } ] } ] }, { "uniprot_ac": "A0AAA9U018", "gene_name": "AIP", "activity": [ { "ec_number": "5.2.1.8", "activity": "[protein]-peptidylproline (omega=180) = [protein]-peptidylproline (omega=0).", "evidence": [ { "id": "A0AAA9U018", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9U018" } ] }, { "ec_number": "5.2.1.8", "activity": "", "evidence": [ { "id": "A0AAA9U018", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9U018" } ] } ] }, { "uniprot_ac": "A0AAF6YJC8", "gene_name": "FKBP6", "activity": [ { "ec_number": "5.2.1.8", "activity": "[protein]-peptidylproline (omega=180) = [protein]-peptidylproline (omega=0).", "evidence": [ { "id": "A0AAF6YJC8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAF6YJC8" } ] }, { "ec_number": "5.2.1.8", "activity": "", "evidence": [ { "id": "A0AAF6YJC8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAF6YJC8" } ] } ] }, { "uniprot_ac": "A0AAF6YJR2", "gene_name": "FKBP3", "activity": [ { "ec_number": "5.2.1.8", "activity": "[protein]-peptidylproline (omega=180) = [protein]-peptidylproline (omega=0).", "evidence": [ { "id": "A0AAF6YJR2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAF6YJR2" } ] }, { "ec_number": "5.2.1.8", "activity": "", "evidence": [ { "id": "A0AAF6YJR2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAF6YJR2" } ] } ] }, { "uniprot_ac": "A0ABI0NKM5", "gene_name": "", "activity": [ { "ec_number": "5.2.1.8", "activity": "[protein]-peptidylproline (omega=180) = [protein]-peptidylproline (omega=0).", "evidence": [ { "id": "A0ABI0NKM5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NKM5" } ] }, { "ec_number": "5.2.1.8", "activity": "", "evidence": [ { "id": "A0ABI0NKM5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NKM5" } ] } ] }, { "uniprot_ac": "A0ABI0NMT7", "gene_name": "", "activity": [ { "ec_number": "5.2.1.8", "activity": "[protein]-peptidylproline (omega=180) = [protein]-peptidylproline (omega=0).", "evidence": [ { "id": "A0ABI0NMT7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NMT7" } ] }, { "ec_number": "5.2.1.8", "activity": "", "evidence": [ { "id": "A0ABI0NMT7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NMT7" } ] } ] }, { "uniprot_ac": "A4FV72", "gene_name": "PPIE", "activity": [ { "ec_number": "5.2.1.8", "activity": "[protein]-peptidylproline (omega=180) = [protein]-peptidylproline (omega=0).", "evidence": [ { "id": "A4FV72", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A4FV72" } ] }, { "ec_number": "5.2.1.8", "activity": "", "evidence": [ { "id": "A4FV72", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A4FV72" } ] } ] }, { "uniprot_ac": "A6QPY8", "gene_name": "PIN4", "activity": [ { "ec_number": "5.2.1.8", "activity": "[protein]-peptidylproline (omega=180) = [protein]-peptidylproline (omega=0).", "evidence": [ { "id": "A6QPY8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A6QPY8" } ] }, { "ec_number": "5.2.1.8", "activity": "", "evidence": [ { "id": "A6QPY8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A6QPY8" } ] } ] }, { "uniprot_ac": "E1B9G4", "gene_name": "PPIL3", "activity": [ { "ec_number": "5.2.1.8", "activity": "[protein]-peptidylproline (omega=180) = [protein]-peptidylproline (omega=0).", "evidence": [ { "id": "E1B9G4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1B9G4" } ] }, { "ec_number": "5.2.1.8", "activity": "", "evidence": [ { "id": "E1B9G4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1B9G4" } ] } ] }, { "uniprot_ac": "F1MNW5", "gene_name": "", "activity": [ { "ec_number": "5.2.1.8", "activity": "[protein]-peptidylproline (omega=180) = [protein]-peptidylproline (omega=0).", "evidence": [ { "id": "F1MNW5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MNW5" } ] }, { "ec_number": "5.2.1.8", "activity": "", "evidence": [ { "id": "F1MNW5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MNW5" } ] } ] }, { "uniprot_ac": "F1MU79", "gene_name": "FKBP4", "activity": [ { "ec_number": "5.2.1.8", "activity": "[protein]-peptidylproline (omega=180) = [protein]-peptidylproline (omega=0).", "evidence": [ { "id": "F1MU79", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MU79" } ] }, { "ec_number": "5.2.1.8", "activity": "", "evidence": [ { "id": "F1MU79", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MU79" } ] } ] }, { "uniprot_ac": "F1N4S5", "gene_name": "FKBP14", "activity": [ { "ec_number": "5.2.1.8", "activity": "[protein]-peptidylproline (omega=180) = [protein]-peptidylproline (omega=0).", "evidence": [ { "id": "F1N4S5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1N4S5" } ] }, { "ec_number": "5.2.1.8", "activity": "", "evidence": [ { "id": "F1N4S5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1N4S5" } ] } ] }, { "uniprot_ac": "F1N6W2", "gene_name": "PPIL4", "activity": [ { "ec_number": "5.2.1.8", "activity": "[protein]-peptidylproline (omega=180) = [protein]-peptidylproline (omega=0).", "evidence": [ { "id": "F1N6W2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1N6W2" } ] }, { "ec_number": "5.2.1.8", "activity": "", "evidence": [ { "id": "F1N6W2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1N6W2" } ] } ] }, { "uniprot_ac": "F6RD06", "gene_name": "FKBP7", "activity": [ { "ec_number": "5.2.1.8", "activity": "[protein]-peptidylproline (omega=180) = [protein]-peptidylproline (omega=0).", "evidence": [ { "id": "F6RD06", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F6RD06" } ] }, { "ec_number": "5.2.1.8", "activity": "", "evidence": [ { "id": "F6RD06", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F6RD06" } ] } ] }, { "uniprot_ac": "G3MXV0", "gene_name": "FKBP5", "activity": [ { "ec_number": "5.2.1.8", "activity": "[protein]-peptidylproline (omega=180) = [protein]-peptidylproline (omega=0).", "evidence": [ { "id": "G3MXV0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3MXV0" } ] }, { "ec_number": "5.2.1.8", "activity": "", "evidence": [ { "id": "G3MXV0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3MXV0" } ] } ] }, { "uniprot_ac": "G3X8B1", "gene_name": "LOC613401", "activity": [ { "ec_number": "5.2.1.8", "activity": "[protein]-peptidylproline (omega=180) = [protein]-peptidylproline (omega=0).", "evidence": [ { "id": "G3X8B1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3X8B1" } ] }, { "ec_number": "5.2.1.8", "activity": "", "evidence": [ { "id": "G3X8B1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3X8B1" } ] } ] }, { "uniprot_ac": "P18203", "gene_name": "FKBP1A", "activity": [ { "ec_number": "5.2.1.8", "activity": "[protein]-peptidylproline 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Acts as a transcriptional repressor via its interaction with EBF1, a transcription factor involved specification of B-cell lineage; this interaction preventing EBF1 to bind DNA and activate target genes.", "evidence": [ { "database": "UniProtKB", "id": "A0A3Q1LPJ4", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1LPJ4#function" }, { "database": "UniProtKB", "id": "ARBA00053645", "url": "https://www.uniprot.org/uniprotkb/ARBA00053645#function" }, { "database": "UniProtKB", "id": "F1N5E2", "url": "https://www.uniprot.org/uniprotkb/F1N5E2#function" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Bos taurus", "taxid": 9913, "evidence": [ { "database": "UniProtKB", "id": "F1N5E2", "url": "https://www.uniprot.org/uniprotkb/F1N5E2" } ], "common_name": "Bovine", "glygen_name": "Bovine", "reference_species": "Bos taurus [9913]" } ], "gene": [ { "name": "ZNF521", "url": "https://www.uniprot.org/uniprotkb/F1N5E2", 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"https://omabrowser.org/oma/group/CDRTFPR/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "A0A3Q1LPJ4", "url": "https://www.orthodb.org/?gene=A0A3Q1LPJ4", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "F1N5E2", "url": "https://www.orthodb.org/?gene=F1N5E2", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR24376", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR24376", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR24376:SF243", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR24376:SF243", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR24376:SF84", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR24376:SF84", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00096", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00096", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF12874", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF12874", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF13912", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF13912", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "XP_005224127", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_005224127", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A3Q1LPJ4", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1LPJ4", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A3Q1LPJ4-1", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1LPJ4-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "F1N5E2", "url": "https://www.uniprot.org/uniprotkb/F1N5E2", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "F1N5E2-1", "url": "https://www.uniprot.org/uniprotkb/F1N5E2-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MSRRKQAKPRSLKDPNCKLEDKTEDGEAIDCKKRPEDGEELEDEAVHSCDSCLQVFESLSDITEHKINQCQLTDGVDVEDDPTCSWPASSPSSKDQTSPSHGEGCDFGEEEGGPGLPYPCQFCDKSFSRLSYLKHHEQSHSDKLPFKCTYCSRLFKHKRSRDRHIKLHTGDKKYHCSECDAAFSRSDHLKIHLKTHTSNKPYKCAICRRGFLSSSSLHGHMQVHERNKDGSQSGSRMEDWKMKDTQKCSQCEEGFDFPEDLQKHIAECHPECSPNEDRAALQCVYCHELFVEETSLMNHMEQMHGGEKKNSCSICSESFHSVEELYSHMDGHQQPESCNHSNSPSLVTVGYTSVSSTTPDSNLSVDSSTMVEAAPPIPKSRGRKRAAQQTPDMTVPSSKQAKVTYSCIYCNKQLFSSLAVLQIHLKTMHLDKPEQAHICQYCLEVLPSLYNLNEHLKQVHEAQDPGLIVSALPAIVYQCNFCSEVVNDLNTLQEHIRCSHGFANPAAKDSNAFFCPHCYMGFLTDSSLEEHIRQVHCDLSGSRFGSPVLGTPKEPVVEVYSCSYCTNSPIFNSVLKLNKHIKENHKNIPLALNYIHNGKKSRALSPLSPVAIEQTSLKMMQAVGGAPARQAGEYICNQCGAKYTSLDGFQTHLKTHLDTVLPKLTCPQCNKEFPNQESLLKHVTIHFMITSTYYICESCDKQFTSVDDLQKHLLDMHTFVFFRCTLCQEVFDSKVSIQLHLAVKHSNEKKVYRCTSCNWDFRNETDLQLHVKHNHLENQGKVHKCIFCGESFGTEVELQCHITTHSKKYNCQFCSKAFHAIILLEKHLREKHCVFDTKTPNCGANGASEPGQKEEVELQTLLTNSQESHNSHDGSEEDVDTSEPMYGCDICGAAYTMETLLQNHQLRDHNIRPGESAIVKKKAELIKGNYKCNVCSRTFFSENGLREHMQTHLGPVKHYMCPICGERFPSLLTLTEHKVTHSKSLDTGNCRICKMPLQSEEEFLEHCQMHPDLRNSLTGFRCVVCMQTVTSTLELKIHGTFHMQKTGNGATVQATGRGPHVPKLYKCASCLKEFRSKQDLVKLDINGLPYGLCAGCVNLSKSASPGVNIAPGSSRPGLGQTENLGAVEGKGKASAPKTRCSSCNVKFESESELQNHIQTVHRELVPDSNSTQLKTPQVSPMPRISPSQSDEKKTYQCIKCQMVFYNEWDIQVHVANHMIDEGLNHECKLCSQTFDSPAKLQCHLIEHSFEGMGGTFKCPVCFTVFVQANKLQQHIFSAHGQEDKIYDCTQCPQKFFFQTELQNHTMTQHSS", "length": 1311, "header": "tr|F1N5E2-1|F1N5E2_BOVIN Isoform 1 of Zinc finger protein 521 OS=Bos taurus OX=9913 GN=ZNF521 PE=3 SV=3 CANONICAL=F1N5E2-1" }, "isoforms": [ { "isoform_ac": "A0A3Q1LPJ4-1", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1LPJ4/entry", "sequence": { "sequence": "MHIWQGCHSVRKDPNCKLEDKTEDGEAIDCKKRPEDGEELEDEAVHSCDSCLQVFESLSDITEHKINQCQLTDGVDVEDDPTCSWPASSPSSKDQTSPSHGEGCDFGEEEGGPGLPYPCQFCDKSFSRLSYLKHHEQSHSDKLPFKCTYCSRLFKHKRSRDRHIKLHTGDKKYHCSECDAAFSRSDHLKIHLKTHTSNKPYKCAICRRGFLSSSSLHGHMQVHERNKDGSQSGSRMEDWKMKDTQKCSQCEEGFDFPEDLQKHIAECHPECSPNEDRAALQCVYCHELFVEETSLMNHMEQMHGGEKKNSCSICSESFHSVEELYSHMDGHQQPESCNHSNSPSLVTVGYTSVSSTTPDSNLSVDSSTMVEAAPPIPKSRGRKRAAQQTPDMTVPSSKQAKVTYSCIYCNKQLFSSLAVLQIHLKTMHLDKPEQAHICQYCLEVLPSLYNLNEHLKQVHEAQDPGLIVSALPAIVYQCNFCSEVVNDLNTLQEHIRCSHGFANPAAKDSNAFFCPHCYMGFLTDSSLEEHIRQVHCDLSGSRFGSPVLGTPKEPVVEVYSCSYCTNSPIFNSVLKLNKHIKENHKNIPLALNYIHNGKKSRALSPLSPVAIEQTSLKMMQAVGGAPARQAGEYICNQCGAKYTSLDGFQTHLKTHLDTVLPKLTCPQCNKEFPNQESLLKHVTIHFMITSTYYICESCDKQFTSVDDLQKHLLDMHTFVFFRCTLCQEVFDSKVSIQLHLAVKHSNEKKVYRCTSCNWDFRNETDLQLHVKHNHLENQGKVHKCIFCGESFGTEVELQCHITTHSKKYNCQFCSKAFHAIILLEKHLREKHCVFDTKTPNCGANGASEPGQKEEVELQTLLTNSQESHNSHDGSEEDVDTSEPMYGCDICGAAYTMETLLQNHQLRDHNIRPGESAIVKKKAELIKGNYKCNVCSRTFFSENGLREHMQTHLGPVKHYMCPICGERFPSLLTLTEHKVTHSKSLDTGNCRICKMPLQSEEEFLEHCQMHPDLRNSLTGFRCVVCMQTVTSTLELKIHGTFHMQKTGNGATVQATGRGPHVPKLYKCASCLKEFRSKQDLVKLDINGLPYGLCAGCVNLSKSASPGVNIAPGSSRPGLGQTENLGAVEGKGKASAPKTRCSSCNVKFESESELQNHIQTVHRELVPDSNSTQLKTPQVSPMPRISPSQSDEKKTYQCIKCQMVFYNEWDIQVHVANHMIDEGLNHECKLCSQTFDSPAKLQCHLIEHSFEGMGGTFKCPVCFTVFVQANKLQQHIFSAHGQEDKIYDCTQCPQKFFFQTELQNHTMTQHSS", "length": 1310, "header": "tr|A0A3Q1LPJ4-1|F1N5E2_BOVIN Computationally mapped isoform of Zinc finger protein 521 OS=Bos taurus OX=9913 GN=ZNF521 PE=3 SV=2 CANONICAL=F1N5E2-1" }, "locus": { "chromosome": "24", "start_pos": 31692122, "end_pos": 31400998, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000081745.2", "url": "https://www.ensembl.org/id/ENSBTAT00000081745.2" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000058853.2", "url": "https://www.ensembl.org/id/ENSBTAP00000058853.2" } ] } }, { "isoform_ac": "F1N5E2-1", "url": "https://www.uniprot.org/uniprotkb/F1N5E2/entry", "sequence": { "sequence": "MSRRKQAKPRSLKDPNCKLEDKTEDGEAIDCKKRPEDGEELEDEAVHSCDSCLQVFESLSDITEHKINQCQLTDGVDVEDDPTCSWPASSPSSKDQTSPSHGEGCDFGEEEGGPGLPYPCQFCDKSFSRLSYLKHHEQSHSDKLPFKCTYCSRLFKHKRSRDRHIKLHTGDKKYHCSECDAAFSRSDHLKIHLKTHTSNKPYKCAICRRGFLSSSSLHGHMQVHERNKDGSQSGSRMEDWKMKDTQKCSQCEEGFDFPEDLQKHIAECHPECSPNEDRAALQCVYCHELFVEETSLMNHMEQMHGGEKKNSCSICSESFHSVEELYSHMDGHQQPESCNHSNSPSLVTVGYTSVSSTTPDSNLSVDSSTMVEAAPPIPKSRGRKRAAQQTPDMTVPSSKQAKVTYSCIYCNKQLFSSLAVLQIHLKTMHLDKPEQAHICQYCLEVLPSLYNLNEHLKQVHEAQDPGLIVSALPAIVYQCNFCSEVVNDLNTLQEHIRCSHGFANPAAKDSNAFFCPHCYMGFLTDSSLEEHIRQVHCDLSGSRFGSPVLGTPKEPVVEVYSCSYCTNSPIFNSVLKLNKHIKENHKNIPLALNYIHNGKKSRALSPLSPVAIEQTSLKMMQAVGGAPARQAGEYICNQCGAKYTSLDGFQTHLKTHLDTVLPKLTCPQCNKEFPNQESLLKHVTIHFMITSTYYICESCDKQFTSVDDLQKHLLDMHTFVFFRCTLCQEVFDSKVSIQLHLAVKHSNEKKVYRCTSCNWDFRNETDLQLHVKHNHLENQGKVHKCIFCGESFGTEVELQCHITTHSKKYNCQFCSKAFHAIILLEKHLREKHCVFDTKTPNCGANGASEPGQKEEVELQTLLTNSQESHNSHDGSEEDVDTSEPMYGCDICGAAYTMETLLQNHQLRDHNIRPGESAIVKKKAELIKGNYKCNVCSRTFFSENGLREHMQTHLGPVKHYMCPICGERFPSLLTLTEHKVTHSKSLDTGNCRICKMPLQSEEEFLEHCQMHPDLRNSLTGFRCVVCMQTVTSTLELKIHGTFHMQKTGNGATVQATGRGPHVPKLYKCASCLKEFRSKQDLVKLDINGLPYGLCAGCVNLSKSASPGVNIAPGSSRPGLGQTENLGAVEGKGKASAPKTRCSSCNVKFESESELQNHIQTVHRELVPDSNSTQLKTPQVSPMPRISPSQSDEKKTYQCIKCQMVFYNEWDIQVHVANHMIDEGLNHECKLCSQTFDSPAKLQCHLIEHSFEGMGGTFKCPVCFTVFVQANKLQQHIFSAHGQEDKIYDCTQCPQKFFFQTELQNHTMTQHSS", "length": 1311, "header": "tr|F1N5E2-1|F1N5E2_BOVIN Isoform 1 of Zinc finger protein 521 OS=Bos taurus OX=9913 GN=ZNF521 PE=3 SV=3 CANONICAL=F1N5E2-1" }, "locus": { "chromosome": "24", "start_pos": 31692122, "end_pos": 31381918, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000048222.5", "url": "https://www.ensembl.org/id/ENSBTAT00000048222.5" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000045301.4", "url": "https://www.ensembl.org/id/ENSBTAP00000045301.4" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [], "orthologs": [ { "uniprot_canonical_ac": "A0A0G2JT53-1", "protein_name": "Zinc finger protein 521", "gene_name": "Zfp521", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MSRRKQAKPRSLKDPNCKLEDKIEDGEAVDCKKRPDDGEELEEDAVHSCDSCLQVFESLSDITEHKIHQCQLTDGVDVEDDPTCSWPASSPSSKDQTSPSHGEGCDFGEEEGGPGLPYPCQFCDKSFSRLSYLKHHEQSHSDKLPFKCTYCSRLFKHKRSRDRHIKLHTGDKKYHCSECDAAFSRSDHLKIHLKTHTSNKPYKCAVCRRGFLSSSSLHGHMQVHERSKDGSQSGSRMEDWKMKDTQKCSQCEEGFDFPEDLQKHIAECHPECSPNEDRAALQCVYCHELFVEETSLMNHIEQVHGGEKKNSCSICSESFLTVEELYSHMDSHQQPESCNHSNSPSLVTVGYTSVSSTTPDSNLSVDSSTMVEAAPPIPKSRGRKRAAQQTSDMTGPSSKQAKVTYSCIYCNKQLFSSLAVLQIHLKTMHLDKPEQAHICQYCLEVLPSLYNLNEHLKQVHEAQDPGLIVSAMPAIIYQCNFCSEVVNDLNTLQEHIRCSHGFANPAAKDSNAFFCPHCYMGFLTDSSLEEHIRQVHCDLSGSRFGSPVLGTPKEPVVEVYSCSYCTNSPIFNSVLKLNKHIKENHKNIPLALNYIHNGKKSRALSPLSPVAIEQTSLKMMQTVGGGPARAAGEYICNQCGAKYTSLDSFQTHLKTHLDTVLPKLTCPQCNKEFPNQESLLKHVTIHFMITSTYYICESCDKQFTSVDDLQKHLLDMHTFVFFRCTLCQEVFDSKVSIQLHLAVKHSNEKKVYRCTSCNWDFRNETDLQLHVKHNHLENQGKVHKCIFCGESFGTEVELQCHITTHSKKYNCRFCSKAFHAVLLLEKHLREKHCVFETKTPNCGTNGASEQVQKEEAELQTLLTNSQESHNSHDGSEEDVDSSEPMYGCDICGAAYTMETLLQNHQLRDHNIRPGESAIVKKKAELIKGNYKCNVCSRTFFSENGLREHMQTHLGPVKHYMCPICGERFPSLLTLTEHKVTHSKSLDTGNCRICKMPLQSEEEFLEHCQMHPDLRNSLTGFRCVVCMQTVTSTLELKIHGTFHMQKTGNGSSVQTTGRGQHVQKLYKCASCLKEFRSKQDLVKLDINGLPYGLCAGCVNLSKSSSPGLGLPPVASRPGLGQNESLSAMEGKGKAGGLKTTRCSSCNVKFESESELQNHIQTVHRELVPDANSTQLKTPQVSPMPRISPSQSDEKKTYQCIKCQMVFYNEWDIQVHVANHMIDEGLNHECKLCSQTFDSPAKLQCHLIEHSFEGMGGTFKCPVCFTVFVQANKLQQHIFSAHGQEDKIYDCTQCPQKFFFQTELQEHFNQEPLQAEGEYAHCP", "length": 1321 }, "evidence": [ { "id": "F1N5E2", "url": "https://omabrowser.org/oma/group/F1N5E2/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "Q6KAS7-1", "protein_name": "Zinc finger protein 521", "gene_name": "Znf521", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MSRRKQAKPRSLKDPNCKLEDKIEDGEAVDCKKRPEDGEELEEDAVHSCDSCLQVFESLSDITEHKIHQCQLTDGVDVEDDPSCSWPASSPSSKDQTSPSHGEGCDFGEEEGGPGLPYPCQFCDKSFSRLSYLKHHEQSHSDKLPFKCTYCSRLFKHKRSRDRHIKLHTGDKKYHCSECDAAFSRSDHLKIHLKTHTSNKPYKCAVCRRGFLSSSSLHGHMQVHERNKDGSQSGSRMEDWKMKDTQKCSQCEEGFDFPEDLQKHIAECHPECSPNEDRAALQCMYCHELFVEETSLMNHIEQVHGGEKKNSCSICSESFLTVEELYSHMDSHQQPESCNHSNSPSLVTVGYTSVSSTTPDSNLSVDSSTMVEAAPPIPKSRGRKRAAQQTSDMTGPSSKQAKVTYSCIYCNKQLFSSLAVLQIHLKTMHLDKPEQAHICQYCLEVLPSLYNLNEHLKQVHEAQDPGLIVSAMPAIVYQCNFCSEVVNDLNTLQEHIRCSHGFANPAAKDSNAFFCPHCYMGFLTDSSLEEHIRQVHCDLSGSRFGSPVLGTPKEPVVEVYSCSYCTNSPIFNSVLKLNKHIKENHKNIPLALNYIHNGKKSRALSPLSPVAIEQTTLKMMQTVGGGPARASGEYICNQCGAKYTSLDSFQTHLKTHLDTVLPKLTCPQCNKEFPNQESLLKHVTIHFMITSTYYICESCDKQFTSVDDLQKHLLDMHTFVFFRCTLCQEVFDSKVSIQLHLAVKHSNEKKVYRCTSCNWDFRNETDLQLHVKHNHLENQGKVHKCIFCGESFGTEVELQCHITTHSKKYNCRFCSKAFHAVILLEKHLREKHCVFETKTPNCGTNGASEQVQKEEAELQTLLTNSQESHNSHDGSEEDVDSSEPMYGCDICGAAYTMETLLQNHQLRDHNIRPGESAIVKKKAELIKGNYKCNVCSRTFFSENGLREHMQTHLGPVKHYMCPICGERFPSLLTLTEHKVTHSKSLDTGNCRICKMPLQSEEEFLEHCQMHPDLRNSLTGFRCVVCMQTVTSTLELKIHGTFHMQKTGNGSSVQTTGRGQHVQKLYKCASCLKEFRSKQDLVKLDINGLPYGLCAGCVNLSKSSSPGLSLPPGASRPGLGQNESLSAMEGKGKAGGLKTRCSSCNVKFESESELQNHIQTVHRELVPDANSTQLKTPQVSPMPRISPSQSDEKKTYQCIKCQMVFYNEWDIQVHVANHMIDEGLNHECKLCSQTFDSPAKLQCHLIEHSFEGMGGTFKCPVCFTVFVQANKLQQHIFSAHGQEDKIYDCTQCPQKFFFQTELQNHTMTQHSS", "length": 1311 }, "evidence": [ { "id": "F1N5E2", "url": "https://omabrowser.org/oma/group/F1N5E2/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q96K83-1", "protein_name": "Zinc finger protein 521", "gene_name": "ZNF521", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MSRRKQAKPRSLKDPNCKLEDKTEDGEALDCKKRPEDGEELEDEAVHSCDSCLQVFESLSDITEHKINQCQLTDGVDVEDDPTCSWPASSPSSKDQTSPSHGEGCDFGEEEGGPGLPYPCQFCDKSFSRLSYLKHHEQSHSDKLPFKCTYCSRLFKHKRSRDRHIKLHTGDKKYHCSECDAAFSRSDHLKIHLKTHTSNKPYKCAICRRGFLSSSSLHGHMQVHERNKDGSQSGSRMEDWKMKDTQKCSQCEEGFDFPEDLQKHIAECHPECSPNEDRAALQCVYCHELFVEETSLMNHMEQVHSGEKKNSCSICSESFHTVEELYSHMDSHQQPESCNHSNSPSLVTVGYTSVSSTTPDSNLSVDSSTMVEAAPPIPKSRGRKRAAQQTPDMTGPSSKQAKVTYSCIYCNKQLFSSLAVLQIHLKTMHLDKPEQAHICQYCLEVLPSLYNLNEHLKQVHEAQDPGLIVSAMPAIVYQCNFCSEVVNDLNTLQEHIRCSHGFANPAAKDSNAFFCPHCYMGFLTDSSLEEHIRQVHCDLSGSRFGSPVLGTPKEPVVEVYSCSYCTNSPIFNSVLKLNKHIKENHKNIPLALNYIHNGKKSRALSPLSPVAIEQTSLKMMQAVGGAPARPTGEYICNQCGAKYTSLDSFQTHLKTHLDTVLPKLTCPQCNKEFPNQESLLKHVTIHFMITSTYYICESCDKQFTSVDDLQKHLLDMHTFVFFRCTLCQEVFDSKVSIQLHLAVKHSNEKKVYRCTSCNWDFRNETDLQLHVKHNHLENQGKVHKCIFCGESFGTEVELQCHITTHSKKYNCKFCSKAFHAIILLEKHLREKHCVFETKTPNCGTNGASEQVQKEEVELQTLLTNSQESHNSHDGSEEDVDTSEPMYGCDICGAAYTMETLLQNHQLRDHNIRPGESAIVKKKAELIKGNYKCNVCSRTFFSENGLREHMQTHLGPVKHYMCPICGERFPSLLTLTEHKVTHSKSLDTGNCRICKMPLQSEEEFLEHCQMHPDLRNSLTGFRCVVCMQTVTSTLELKIHGTFHMQKTGNGSAVQTTGRGQHVQKLYKCASCLKEFRSKQDLVKLDINGLPYGLCAGCVNLSKSASPGINVPPGTNRPGLGQNENLSAIEGKGKVGGLKTRCSSCNVKFESESELQNHIQTIHRELVPDSNSTQLKTPQVSPMPRISPSQSDEKKTYQCIKCQMVFYNEWDIQVHVANHMIDEGLNHECKLCSQTFDSPAKLQCHLIEHSFEGMGGTFKCPVCFTVFVQANKLQQHIFSAHGQEDKIYDCTQCPQKFFFQTELQNHTMTQHSS", "length": 1311 }, "evidence": [ { "id": "F1N5E2", "url": "https://omabrowser.org/oma/group/F1N5E2/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" } ], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 2, "go_terms": [ { "name": "nucleus", "id": "GO:0005634", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005634", "evidence": [ { "database": "UniProtKB", "id": "F1N5E2", "url": "https://www.uniprot.org/uniprotkb/F1N5E2" } ], "pmid": "" }, { "name": "nucleoplasm", "id": "GO:0005654", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005654", "evidence": [ { "database": "UniProtKB", "id": "F1N5E2", "url": "https://www.uniprot.org/uniprotkb/F1N5E2" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 3, "go_terms": [ { "name": "DNA-templated transcription", "id": "GO:0006351", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006351", "evidence": [ { "database": "UniProtKB", "id": "F1N5E2", "url": "https://www.uniprot.org/uniprotkb/F1N5E2" } ], "pmid": "" }, { "name": "regulation of transcription by RNA polymerase II", "id": "GO:0006357", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006357", "evidence": [ { "database": "UniProtKB", "id": "F1N5E2", "url": "https://www.uniprot.org/uniprotkb/F1N5E2" } ], "pmid": "" }, { "name": "cell differentiation", "id": "GO:0030154", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030154", "evidence": [ { "database": "UniProtKB", "id": "F1N5E2", "url": "https://www.uniprot.org/uniprotkb/F1N5E2" } ], "pmid": "" } ] }, { "name": "Molecular Function", "total": 4, "go_terms": [ { "name": "zinc ion binding", "id": "GO:0008270", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008270", "evidence": [ { "database": "UniProtKB", "id": "F1N5E2", "url": "https://www.uniprot.org/uniprotkb/F1N5E2" } ], "pmid": "" }, { "name": "transcription cis-regulatory region binding", "id": "GO:0000976", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000976", "evidence": 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"MRGRRGRPPKQPAAPAAERCAPAPPPPPPPPPTSGPIGGLRSRHRGSSRGRWAAAQAEVAPKTRLSSPRGGSSSRRKPPPPPPPPAPPSTSAPGRGGRGGGGGRTGGGGGGGHLARTTPARRAVNKVVYDDHESEEEEEEEDMVSEEEEEEEDGDAEETQDSEDEEEDEMEEDDDDSDYPEEMEDDDDDDASYCTESSFRSHSTYSSTPGRRKPRVHRPRSPILEEKDIPPLEFPKSSEDLMVPNEHIMNVIAIYEVLRNFGTVLRLSPFRFEDFCAALVSQEQCTLMAEMHVVLLKAVLREEDTSNTTFGPADLKDSVNSTLYFIDGMTWPEVLRVYCESDKEYHHVLPYQEAEDYPYGPVENKIKVLQFLVDQFLTTNIAREELMSEGVIQYDDHCRVCHKLGDLLCCETCSAVYHLECVKPPLEEVPEDEWQCEVCVAHKVPGVTDCVAEIQKNKPYIRHEPIGYDRSRRKYWFLNRRLIIEEDTENENEKKIWYYSTKVQLAELIDCLDKDYWEAELCKILEEMREEIHRHMDITEDLTNKARGSNKSFLAAANEEILESIRAKKGDIDIVKSPEEIDKDKNETETSNSKDAEKSREEFEDQIVEKDSDDKTPDDVDPEQGKSEEPTEVGDKGNSVSANLGDNTTNASSEETVPSEGRSPMGCVSETHDSSNMAEKKVASELPQDVPEEPNKTCDSSNPSATTASIQPNLEHSNSSSELSSSQSEPAKAADDPENGERESHTPVSIQEEIGDFKSEKSNGEISESPGGGRGASGSTRIITRLRNPDSKLSQLKSQQVAAAAHEANKLFKEGKEVLVVNSQGEISRLSTKKEVVMKGNINNYFKLGQEGKYRVYHNQYSTNSFALNKHQHREDHDKRRHLAHKFCLTPAGEFKWNGSVHGSKVLTISTLRLTITQLENNIPSSFLHPNWASHRANWIKAVQMCSKPREFALALAILECAVKPVVMLPIWRESLGHTRLHRMTSIEREEKEKVKKKEKKQEEEETMQQATWVKYTFPVKHQVWKQKGEEYRVTGYGGWSWISKTHVYRFVPKLPGNTNVHYRKSVEGVKNNMDENMDESDRRKSPRSPKKIKTEPDSEKGEVKDSDAAKGADQSEMDISKVTEKKDQDVKEVLDSDNDKSFKEEPMEIDDDVKTESHLNCQESSQVDVVNVSEGFHLRTSYKKKIKSSKLDGLLERRIKQFTLEEKQRHEKMKLEGGIKGSGKTPTSSVKSLSESPVITKVKEGCQSDLLTQEQSSNTSNNKSEDSTRGCSQSDSSILGITDPDHTANKLYSKDQMLEDVSIQSADTHCQKQNSVRNDMDEGLSDPASEGQEPSKMKTKGTDFLIDDPKLASADEIGTLIYKNRKPFIQEDNDTTVCPSQSPLLPSVPKSTDDRDIPSLSKAVDFEGKLGCDSEYNSTLENSSDTMSVQDSSEEDMIVQNSNESISEQLITQEQGSEGFEPLKREFVSDKTTGSCDDRLQSKVNDANGRKPSQDQKLEDRPLNKCIDQNSLKSVTDKKNNENRESEKKGQKASTFQINGKDNKAKVYLKGECLRDISESKIGSGDIEPKVNNINKIIPENDIKPLTVKESTVKPFMNGDVIMEDFNEKNNLETKSCLLRSSDAEGDYHDSLETLPSTKESESAQAAMPLPSCPEGSSSNQVEDMEIDISKVKKVTSSPVTSGEESNLSNDFIDENGLPTNKDENVNGEPKRKTVITEVTTMTSTVATESKTVIKVAKGDKQTVVSSTENCAKSTVTTTTTTVTKLSTPSAGSDVDIISVKEQSKTVVTTTVTDSLTTAGGTLVTSMTVSKEYSTRDKVKLMKFSRPKKTRSGTALPSYRKFITKSSKKSIFVLPNDDLKKLARKGGIREVPYFNYNAKPALDIWPYPSPRPTFGITWRYRLQTVKSLAGVSLMLRLLWASLRWDDMAAKAPPGGGTTRTETSETEITTTEIIKRRDVGPYGIRSEYCIRKIICPIGVPEAPKETPTPQRKGLRSSALRPKRPETPKQTGPVIIETWVAEEELELWEIRAFAERVEKEKAQAVEQQAKKRLEQQKPTVIAASTTSPTNSTTSTISPAQKVMVAPISGSVTTGTKMVLTTKVGSPATVTFQQNKNFHQTFATWVKQGQSNSGVVQVQQKVLGIIPSSTGASQQTFTSFQPRTATVTIRPNTSGSGGTTTTSQVITGPQIRPGMTVIRTPLQQSTLGKAIIRTPVMVQPGAPQQVVTQIIRGQPVSTAISAPSTVSSTPAQKGLSSGTSTANLQPSTSQPPRPQQGQVKLTMAQLTQLTQGHGGNQGLTVVIQGQGQTTGQLQLIPQGVTILPGPGQQLMQAAMPNGTVQRFLFTPLATTAATTSSTTTTVSTTAAGTSEQRQSKLSSPTQVQPAKSLPPAPPSSVSPPEAQPQPAQPAQPSAQPSAQPQPQTQSPSPAQPETQTQPEVQTQTTVASHVPPEAQPTQAQSSKPQVAGQCPPQSNVQGQSPARVQSPPQTRVRPSTPSQVSPGQQAQGQTPASQPIPIQPHTSLPTPSQGQPQSQPQVQSSTQTLSPGQTLSQVAVSSPPRPPLQVPQPQPQVLAVPQLPPQVQVLSQIQPQVVAQIQAQQGGVPQQIKLQLPVQIQQSSPVQTHHIQNVVAVQAASVQEQLQRVQQLRDQQQKKKQQQIEIKREHTLQASNQSEIIQKQVVMKHNAVIEHLKQKKTMTPAEREENQRMIVCNQVMKYILDKIDKEEKQAAKKRKREESVEQKRSKQNASKLSALLFKHKEQLKAEILKKRALLDKDLQIEVQEELKRDLKIKKEKDMVQATAVAATCPAAPPAPPAPPPSPPPPPPPQHPGPLATATTTLPVASQKRKREEERDSNSKSKKKKMISTTSKETKKDTKLYCICKTPYDESKFYIGCDRCQNWYHGRCVGILQSEAELIDEYVCPQCQSTEDAMTVLTPLTEKDYEGLKRVLRSLQAHKMAWPFLEPVDPNDAPDYYGVIKEPMDLATMEERVQRRYYEKLTEFVADMTKIFDNCRYYNPSDSPFYQCAEVLESFFVQKLKGFKASRSHNNKLQSTAS", "length": 3055, "header": "tr|F1N3U7-1|F1N3U7_BOVIN Isoform 1 of Bromodomain PHD finger transcription factor OS=Bos taurus OX=9913 GN=BPTF PE=4 SV=3 CANONICAL=F1N3U7-1" }, "isoforms": [ { "isoform_ac": "A0A3Q1LTZ2-1", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1LTZ2/entry", "sequence": { "sequence": "MRGRRGRPPKQPAAPAAERCAPAPPPPPPPPPTSGPIGGLRSRHRGSSRGRWAAAQAEVAPKTRLSSPRGGSSSRRKPPPPPPPPAPPSTSAPGRGGRGGGGGRTGGGGGGGHLARTTPARRAVNKVVYDDHESEEEEEEEDMVSEEEEEEEDGDAEETQDSEDEEEDEMEEDDDDSDYPEEMEDDDDDDASYCTESSFRSHSTYSSTPGRRKPRVHRPRSPILEEKDIPPLEFPKSSEDLMVPNEHIMNVIAIYEVLRNFGTVLRLSPFRFEDFCAALVSQEQCTLMAEMHVVLLKAVLREEDTSNTTFGPADLKDSVNSTLYFIDGMTWPEVLRVYCESDKEYHHVLPYQEAEDYPYGPVENKIKVLQFLVDQFLTTNIAREELMSEGVIQYDDHCRVCHKLGDLLCCETCSAVYHLECVKPPLEEVPEDEWQCEVCVAHKVPGVTDCVAEIQKNKPYIRHEPIGYDRSRRKYWFLNRRLIIEEDTENENEKKIWYYSTKVQLAELIDCLDKDYWEAELCKILEEMREEIHRHMDITEDLTNKARGSNKSFLAAANEEILESIRAKKGDIDIVKSPEEIDKDKNETETSNSKDAEKSREEFEDQIVEKDSDDKTPDDVDPEQGKSEEEPNKTCDSSNPSATTASIQPNLEHSNSSSELSSSQSEPAKAADDPENGERESHTPVSIQEEIGDFKSEKSNGEISESPGGGRGASGSTRIITRLRNPDSKLSQLKSQQVAAAAHEANKLFKEGKEVLVVNSQGEISRLSTKKEVVMKGNINNYFKLGQEGKYRVYHNQYSTNSFALNKHQHREDHDKRRHLAHKFCLTPAGEFKWNGSVHGSKVLTISTLRLTITQLENNIPSSFLHPNWASHRANWIKAVQMCSKPREFALALAILECAVKPVVMLPIWRESLGHTRLHRMTSIEREEKEKVKKKEKKQEEEETMQQATWVKYTFPVKHQVWKQKGEEYRVTGYGGWSWISKTHVYRFVPKLPGNTNVHYRKSVEGVKNNMDENMDESDRRKSPRSPKKIKTEPDSEKGEVKDSDAAKGADQSEMDISKVTEKKDQDVKEVLDSDNDKSFKEEPMEIDDDVKTESHLNCQESSQVDVVNVSEGFHLRTSYKKKIKSSKLDGLLERRIKQFTLEEKQRHEKMKLEGGIKGSGKTPTSSVKSLSESPVITKVKEGCQSDLLTQEQSSNTSNNKSEDSTRGCSQSDSSILGITDPDHTANKLYSKDQMLEDVSIQSADTHCQKQNSVRNDMDEGLSDPASEGQEPSKMKTKGTDFLIDDPKLASADEIGTLIYKNRKPFIQEDNDTTVCPSQSPLLPSVPKSTDDRDIPSLSKAVDFEGKLGCDSEYNSTLENSSDTMSVQDSSEEDMIVQNSNESISEQLITQEQGSEGFEPLKREFVSDKTTGSCDDRLQSKVNDANGRKPSQDQKLEDRPLNKCIDQNSLKSVTDKKNNENRESEKKGQKASTFQINGKDNKAKVYLKGECLRDISESKIGSGDIEPKVNNINKIIPENDIKPLTVKESTVKPFMNGDVIMEDFNEKNNLETKSCLLRSSDAEGDYHDSLETLPSTKESESAQAAMPLPSCPEGSSSNQVEDMEIDISKVKKVTSSPVTSGEESNLSNDFIDENGLPTNKDENVNGEPKRKTVITEVTTMTSTVATESKTVIKVAKGDKQTVVSSTENCAKSTVTTTTTTVTKLSTPSAGSDVDIISVKEQSKTVVTTTVTDSLTTAGGTLVTSMTVSKEYSTRDKVKLMKFSRPKKTRSGTALPSYRKFITKSSKKSIFVLPNDDLKKLARKGGIREVPYFNYNAKPALDIWPYPSPRPTFGITWRYRLQTVKSLAGVSLMLRLLWASLRWDDMAAKAPPGGGTTRTETSETEITTTEIIKRRDVGPYGIRSEYCIRKIICPIGVPEAPKETPTPQRKGLRSSALRPKRPETPKQTGPVIIETWVAEEELELWEIRAFAERVEKEKAQAVEQQAKVSEQKKAEDFKAQMEAHLKQQRLAAQQKRLEQQKPTVIAASTTSPTNSTTSTISPAQKVMVAPISGSVTTGTKMVLTTKVGSPATVTFQQNKNFHQTFATWVKQGQSNSGVVQVQQKVLGIIPSSTGASQQTFTSFQPRTATVTIRPNTSGSGGTTTTSQVITGPQIRPGMTVIRTPLQQSTLGKAIIRTPVMVQPGAPQQVVTQIIRGQPVSTAISAPSTVSSTPAQKGLSSGTSTANLQPSTSQPPRPQQGQVKLTMAQLTQLTQGHGGNQGLTVVIQGQGQTTGQLQLIPQGVTILPGPGQQLMQAAMPNGTVQRFLFTPLATTAATTSSTTTTVSTTAAGTSEQRQSKLSSPTQVQPAKSLPPAPPSSVSPPEAQPQPAQPAQPSAQPSAQPQPQTQSPSPAQPETQTQPEVQTQTTVASHVPPEAQPTQAQSSKPQVAGQCPPQSNVQGQSPARVQSPPQTRVRPSTPSQVSPGQQAQGQTPASQPIPIQPHTSLPTPSQGQPQSQPQVVMKHNAVIEHLKQKKTMTPAEREENQRMIVCNQVMKYILDKIDKEEKQAAKKRKREESVEQKRSKQNASKLSALLFKHKEQLKAEILKKRALLDKDLQIEVQEELKRDLKIKKEKDMVQATAVAATCPAAPPAPPAPPPSPPPPPPPQHPGPLATATTTLPVASQKRKREEERDSNSKSKKKKMISTTSKETKKDTKLYCICKTPYDESKFYIGCDLCTNWYHGECVGITEKEAKKMDVYICNDCKRAQEGNSEELYCICRTPYDESQFYIGCDRCQNWYHGRCVGILQSEAELIDEYVCPQCQSTEDAMTVLTPLTEKDYEGLKRVLRSLQAHKMAWPFLEPVDPNDAPDYYGVIKEPMDLATMEERVQRRYYEKLTEFVADMTKIFDNCRYYNPSDSPFYQCAEVLESFFVQKLKGFKASRSHNNKLQSTAS", "length": 2934, "header": "tr|A0A3Q1LTZ2-1|F1N3U7_BOVIN Computationally mapped isoform of Bromodomain PHD finger transcription factor OS=Bos taurus OX=9913 GN=BPTF PE=4 SV=3 CANONICAL=F1N3U7-1" }, "locus": { "chromosome": "19", "start_pos": 49128161, "end_pos": 48997284, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000085150.3", "url": "https://www.ensembl.org/id/ENSBTAT00000085150.3" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000058644.3", "url": "https://www.ensembl.org/id/ENSBTAP00000058644.3" } ] } }, { "isoform_ac": "A0A3Q1MBT8-1", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1MBT8/entry", "sequence": { "sequence": "MRGRRGRPPKQPAAPAAERCAPAPPPPPPPPPTSGPIGGLRSRHRGSSRGRWAAAQAEVAPKTRLSSPRGGSSSRRKPPPPPPPPAPPSTSAPGRGGRGGGGGRTGGGGGGGHLARTTPARRAVNKVVYDDHESEEEEEEEDMVSEEEEEEEDGDAEETQDSEDEEEDEMEEDDDDSDYPEEMEDDDDDDASYCTESSFRSHSTYSSTPGRRKPRVHRPRSPILEEKDIPPLEFPKSSEDLMVPNEHIMNVIAIYEVLRNFGTVLRLSPFRFEDFCAALVSQEQCTLMAEMHVVLLKAVLREEDTSNTTFGPADLKDSVNSTLYFIDGMTWPEVLRVYCESDKEYHHVLPYQEAEDYPYGPVENKIKVLQFLVDQFLTTNIAREELMSEGVIQYDDHCRVCHKLGDLLCCETCSAVYHLECVKPPLEEVPEDEWQCEVCVAHKVPGVTDCVAEIQKNKPYIRHEPIGYDRSRRKYWFLNRRLIIEEDTENENEKKIWYYSTKVQLAELIDCLDKDYWEAELCKILEEMREEIHRHMDITEDLTNKARGSNKSFLAAANEEILESIRAKKGDIDIVKSPEEIDKDKNETETSNSKDAEKSREEFEDQIVEKDSDDKTPDDVDPEQGKSEEPTEVGDKGNSVSANLGDNTTNASSEETVPSEGRSPMGCVSETHDSSNMAEKKVASELPQDVPEEPNKTCDSSNPSATTASIQPNLEHSNSSSELSSSQSEPAKAADDPENGERESHTPVSIQEEIGDFKSEKSNGEISESPGGGRGASGSTRIITRLRNPDSKLSQLKSQQVAAAAHEANKLFKEGKEVLVVNSQGEISRLSTKKEVVMKGNINNYFKLGQEGKYRVYHNQYSTNSFALNKHQHREDHDKRRHLAHKFCLTPAGEFKWNGSVHGSKVLTISTLRLTITQLENNIPSSFLHPNWASHRANWIKAVQMCSKPREFALALAILECAVKPVVMLPIWRESLGHTRLHRMTSIEREEKEKVKKKEKKQEEEETMQQATWVKYTFPVKHQVWKQKGEEYRVTGYGGWSWISKTHVYRFVPKLPGNTNVHYRKSVEGVKNNMDENMDESDRRKSPRSPKKIKTEPDSEKGEVKDSDAAKGADQSEMDISKVTEKKDQDVKEVLDSDNDKSFKEEPMEIDDDVKTESHLNCQESSQVDVVNVSEGFHLRTSYKKKIKSSKLDGLLERRIKQFTLEEKQRHEKMKLEGGIKGSGKTPTSSVKSLSESPVITKVKEGCQSDLLTQEQSSNTSNNKSEDSTRGCSQSDSSILGITDPDHTANKLYSKDQMLEDVSIQSADTHCQKQNSVRNDMDEGLSDPASEGQEPSKMKTKGTDFLIDDPKLASADEIGTLIYKNRKPFIQEDNDTTVCPSQSPLLPSVPKSTDDRDIPSLSKAVDFEGKLGCDSEYNSTLENSSDTMSVQDSSEEDMIVQNSNESISEQLITQEQGSEGFEPLKREFVSDKTTGSCDDRLQSKVNDANGRKPSQDQKLEDRPLNKCIDQNSLKSVTDKKNNENRESEKKGQKASTFQINGKDNKAKVYLKGECLRDISESKIGSGDIEPKVNNINKIIPENDIKPLTVKESTVKPFMNGDVIMEDFNEKNNLETKSCLLRSSDAEGDYHDSLETLPSTKESESAQAAMPLPSCPEGSSSNQVEDMEIDISKVKKVTSSPVTSGEESNLSNDFIDENGLPTNKDENVNGEPKRKTVITEVTTMTSTVATESKTVIKVAKGDKQTVVSSTENCAKSTVTTTTTTVTKLSTPSAGSDVDIISVKEQSKTVVTTTVTDSLTTAGGTLVTSMTVSKEYSTRDKVKLMKFSRPKKTRSGTALPSYRKFITKSSKKSIFVLPNDDLKKLARKGGIREVPYFNYNAKPALDIWPYPSPRPTFGITWRYRLQTVKSLAGVSLMLRLLWASLRWDDMAAKAPPGGGTTRTETSETEITTTEIIKRRDVGPYGIRSEYCIRKIICPIGVPEAPKETPTPQRKGLRSSALRPKRPETPKQTGPVIIETWVAEEELELWEIRAFAERVEKEKAQAVEQQAKVSEQKKAEDFKAQMEAHLKQQRLAAQQKRLEQQKPTVIAASTTSPTNSTTSTISPAQKVMVAPISGSVTTGTKMVLTTKVGSPATVTFQQNKNFHQTFATWVKQGQSNSGVVQVQQKVLGIIPSSTGASQQTFTSFQPRTATVTIRPNTSGSGGTTTTSQVITGPQIRPGMTVIRTPLQQSTLGKAIIRTPVMVQPGAPQQVVTQIIRGQPVSTAISAPSTVSSTPAQKGLSSGTSTANLQPSTSQPPRPQQGQVKLTMAQLTQLTQGHGGNQGLTVVIQGQGQTTGQLQLIPQGVTILPGPGQQLMQAAMPNGTVQRFLFTPLATTAATTSSTTTTVSTTAAGTSEQRQSKLSSPTQVQPAKSLPPAPPSSVSPPEAQPQPAQPAQPSAQPSAQPQPQTQSPSPAQPETQTQPEVQTQTTVASHVPPEAQPTQAQSSKPQVAGQCPPQSNVQGQSPARVQSPPQTRVRPSTPSQVSPGQQAQGQTPASQPIPIQPHTSLPTPSQGQPQSQPQVVMKHNAVIEHLKQKKTMTPAEREENQRMIVCNQVMKYILDKIDKEEKQAAKKRKREESVEQKRSKQNASKLSALLFKHKEQLKAEILKKRALLDKDLQIEVQEELKRDLKIKKEKDMVQATAVAATCPAAPPAPPAPPPSPPPPPPPQHPGPLATATTTLPVASQKRKREEERDSNSKSKKKKMISTTSKETKKDTKLYCICKTPYDESKFYIGCDLCTNWYHGECVGITEKEAKKMDVYICNDCKRAQEGNSEELYCICRTPYDESQFYIGCDRCQNWYHGRCVGILQSEAELIDEYVCPQCQSTEDAMTVLTPLTEKDYEGLKRVLRSLQAHKMAWPFLEPVDPNDAPDYYGVIKEPMDLATMEERVQRRYYEKLTEFVADMTKIFDNCRYYNPSDSPFYQCAEVLESFFVQKLKGFKASRL", "length": 2987, "header": "tr|A0A3Q1MBT8-1|A0A3Q1MBT8_BOVIN Computationally mapped isoform of Bromodomain PHD finger transcription factor OS=Bos taurus OX=9913 GN=BPTF PE=4 SV=3 CANONICAL=F1N3U7-1" }, "locus": { "chromosome": "19", "start_pos": 49128161, "end_pos": 48998119, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000081090.3", "url": "https://www.ensembl.org/id/ENSBTAT00000081090.3" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000068231.3", "url": "https://www.ensembl.org/id/ENSBTAP00000068231.3" } ] } }, { "isoform_ac": "F1N3U7-1", "url": "https://www.uniprot.org/uniprotkb/F1N3U7/entry", "sequence": { "sequence": "MRGRRGRPPKQPAAPAAERCAPAPPPPPPPPPTSGPIGGLRSRHRGSSRGRWAAAQAEVAPKTRLSSPRGGSSSRRKPPPPPPPPAPPSTSAPGRGGRGGGGGRTGGGGGGGHLARTTPARRAVNKVVYDDHESEEEEEEEDMVSEEEEEEEDGDAEETQDSEDEEEDEMEEDDDDSDYPEEMEDDDDDDASYCTESSFRSHSTYSSTPGRRKPRVHRPRSPILEEKDIPPLEFPKSSEDLMVPNEHIMNVIAIYEVLRNFGTVLRLSPFRFEDFCAALVSQEQCTLMAEMHVVLLKAVLREEDTSNTTFGPADLKDSVNSTLYFIDGMTWPEVLRVYCESDKEYHHVLPYQEAEDYPYGPVENKIKVLQFLVDQFLTTNIAREELMSEGVIQYDDHCRVCHKLGDLLCCETCSAVYHLECVKPPLEEVPEDEWQCEVCVAHKVPGVTDCVAEIQKNKPYIRHEPIGYDRSRRKYWFLNRRLIIEEDTENENEKKIWYYSTKVQLAELIDCLDKDYWEAELCKILEEMREEIHRHMDITEDLTNKARGSNKSFLAAANEEILESIRAKKGDIDIVKSPEEIDKDKNETETSNSKDAEKSREEFEDQIVEKDSDDKTPDDVDPEQGKSEEPTEVGDKGNSVSANLGDNTTNASSEETVPSEGRSPMGCVSETHDSSNMAEKKVASELPQDVPEEPNKTCDSSNPSATTASIQPNLEHSNSSSELSSSQSEPAKAADDPENGERESHTPVSIQEEIGDFKSEKSNGEISESPGGGRGASGSTRIITRLRNPDSKLSQLKSQQVAAAAHEANKLFKEGKEVLVVNSQGEISRLSTKKEVVMKGNINNYFKLGQEGKYRVYHNQYSTNSFALNKHQHREDHDKRRHLAHKFCLTPAGEFKWNGSVHGSKVLTISTLRLTITQLENNIPSSFLHPNWASHRANWIKAVQMCSKPREFALALAILECAVKPVVMLPIWRESLGHTRLHRMTSIEREEKEKVKKKEKKQEEEETMQQATWVKYTFPVKHQVWKQKGEEYRVTGYGGWSWISKTHVYRFVPKLPGNTNVHYRKSVEGVKNNMDENMDESDRRKSPRSPKKIKTEPDSEKGEVKDSDAAKGADQSEMDISKVTEKKDQDVKEVLDSDNDKSFKEEPMEIDDDVKTESHLNCQESSQVDVVNVSEGFHLRTSYKKKIKSSKLDGLLERRIKQFTLEEKQRHEKMKLEGGIKGSGKTPTSSVKSLSESPVITKVKEGCQSDLLTQEQSSNTSNNKSEDSTRGCSQSDSSILGITDPDHTANKLYSKDQMLEDVSIQSADTHCQKQNSVRNDMDEGLSDPASEGQEPSKMKTKGTDFLIDDPKLASADEIGTLIYKNRKPFIQEDNDTTVCPSQSPLLPSVPKSTDDRDIPSLSKAVDFEGKLGCDSEYNSTLENSSDTMSVQDSSEEDMIVQNSNESISEQLITQEQGSEGFEPLKREFVSDKTTGSCDDRLQSKVNDANGRKPSQDQKLEDRPLNKCIDQNSLKSVTDKKNNENRESEKKGQKASTFQINGKDNKAKVYLKGECLRDISESKIGSGDIEPKVNNINKIIPENDIKPLTVKESTVKPFMNGDVIMEDFNEKNNLETKSCLLRSSDAEGDYHDSLETLPSTKESESAQAAMPLPSCPEGSSSNQVEDMEIDISKVKKVTSSPVTSGEESNLSNDFIDENGLPTNKDENVNGEPKRKTVITEVTTMTSTVATESKTVIKVAKGDKQTVVSSTENCAKSTVTTTTTTVTKLSTPSAGSDVDIISVKEQSKTVVTTTVTDSLTTAGGTLVTSMTVSKEYSTRDKVKLMKFSRPKKTRSGTALPSYRKFITKSSKKSIFVLPNDDLKKLARKGGIREVPYFNYNAKPALDIWPYPSPRPTFGITWRYRLQTVKSLAGVSLMLRLLWASLRWDDMAAKAPPGGGTTRTETSETEITTTEIIKRRDVGPYGIRSEYCIRKIICPIGVPEAPKETPTPQRKGLRSSALRPKRPETPKQTGPVIIETWVAEEELELWEIRAFAERVEKEKAQAVEQQAKKRLEQQKPTVIAASTTSPTNSTTSTISPAQKVMVAPISGSVTTGTKMVLTTKVGSPATVTFQQNKNFHQTFATWVKQGQSNSGVVQVQQKVLGIIPSSTGASQQTFTSFQPRTATVTIRPNTSGSGGTTTTSQVITGPQIRPGMTVIRTPLQQSTLGKAIIRTPVMVQPGAPQQVVTQIIRGQPVSTAISAPSTVSSTPAQKGLSSGTSTANLQPSTSQPPRPQQGQVKLTMAQLTQLTQGHGGNQGLTVVIQGQGQTTGQLQLIPQGVTILPGPGQQLMQAAMPNGTVQRFLFTPLATTAATTSSTTTTVSTTAAGTSEQRQSKLSSPTQVQPAKSLPPAPPSSVSPPEAQPQPAQPAQPSAQPSAQPQPQTQSPSPAQPETQTQPEVQTQTTVASHVPPEAQPTQAQSSKPQVAGQCPPQSNVQGQSPARVQSPPQTRVRPSTPSQVSPGQQAQGQTPASQPIPIQPHTSLPTPSQGQPQSQPQVQSSTQTLSPGQTLSQVAVSSPPRPPLQVPQPQPQVLAVPQLPPQVQVLSQIQPQVVAQIQAQQGGVPQQIKLQLPVQIQQSSPVQTHHIQNVVAVQAASVQEQLQRVQQLRDQQQKKKQQQIEIKREHTLQASNQSEIIQKQVVMKHNAVIEHLKQKKTMTPAEREENQRMIVCNQVMKYILDKIDKEEKQAAKKRKREESVEQKRSKQNASKLSALLFKHKEQLKAEILKKRALLDKDLQIEVQEELKRDLKIKKEKDMVQATAVAATCPAAPPAPPAPPPSPPPPPPPQHPGPLATATTTLPVASQKRKREEERDSNSKSKKKKMISTTSKETKKDTKLYCICKTPYDESKFYIGCDRCQNWYHGRCVGILQSEAELIDEYVCPQCQSTEDAMTVLTPLTEKDYEGLKRVLRSLQAHKMAWPFLEPVDPNDAPDYYGVIKEPMDLATMEERVQRRYYEKLTEFVADMTKIFDNCRYYNPSDSPFYQCAEVLESFFVQKLKGFKASRSHNNKLQSTAS", "length": 3055, "header": "tr|F1N3U7-1|F1N3U7_BOVIN Isoform 1 of Bromodomain PHD finger transcription factor OS=Bos taurus OX=9913 GN=BPTF PE=4 SV=3 CANONICAL=F1N3U7-1" }, "locus": { "chromosome": "19", "start_pos": 49128161, "end_pos": 48997284, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000019440.7", "url": "https://www.ensembl.org/id/ENSBTAT00000019440.7" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000019440.7", "url": "https://www.ensembl.org/id/ENSBTAP00000019440.7" } ] } } ], "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "other", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 208, "start_aa": "Thr", "end_pos": 208, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr208", "evidence": [ { "id": "", 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"Protein Classification", "Other" ] }, { "id": "PF00595", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00595", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF09379", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF09379", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF09380", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF09380", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "A0A3Q1MGA7", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1MGA7", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A3Q1MGA7-1", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1MGA7-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0AAA9SX83", "url": "https://www.uniprot.org/uniprotkb/A0AAA9SX83", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0AAA9SX83-1", "url": "https://www.uniprot.org/uniprotkb/A0AAA9SX83-1", "database": 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"length": 1305, "header": "tr|F1N2X3-1|F1N2X3_BOVIN Isoform 1 of FERM and PDZ domain containing 2 OS=Bos taurus OX=9913 GN=FRMPD2 PE=4 SV=4 CANONICAL=F1N2X3-1" }, "isoforms": [ { "isoform_ac": "A0A3Q1MGA7-1", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1MGA7/entry", "sequence": { "sequence": "TQPLTQDAGMSPASVTLASALQVRGEALSEEDIWSLLSLATERLLEDLCDDSSNYVVCPWSVLLSATGSLSFQDHVSHIEAAPFKAPELLQGQSNDEQLGASQMHVYSLGMTLYWSAGFHVPSNQPLQLCQPLHSILLTMCEDQPGRRLPLQSVLEACQIHWEEAAVHPTSANLHVRQLVGLVLGTISEVERRAVEESSSGQRDRSHLLRNRLHQASCESQAAWALGCAHRCRVSERSTETQSSLEPGLNTSARGRCSLAVNSALPVQVPPDLQEGRRLSSASALPENSQPATPSQRGFLQRKGKFSRPEFVLMAGEAPVTLYLPGSIVTKRAKSYLALRDLCVVLLSGQCLEVKCDITSTVGAVFSAIASFASLGELTYFGLAYMKGKEFFFLDAETRLCKIAPEGWSEQPQKKSSPNAFVLFLRIKFFVSHYGLLQHSWTRHQFYLQLRKDILEEKLYCSDEMLLQLGVLALQAEFGSYPEEQVENKAYFRVEDYIPASLIERMTALRAQVEVSEMHRLSPMLWGEDAELEFLRVAQQLPEYGVLVYQVLPEKTRLEGEMALGICAKGVIVYEVRNNSRIATLRFQWREIEKILAYRKKFIITSSVTGKKHTFVADSVKTCKYLLGLCCAQHGFNAQMSSPGVTSDSDKCVQMASLSLAHLAQSNQLTWIQRLSSSENALFIPGLEDAAGGLLRRSLDNFTMDTSKGTRAQGLRGSPCLGREQLERLCLIQKPTTCDLLSRQPAQSMRTGSRNNRRRSFIAEPDGEIVHVTLSRDPHRGFGFVINEGEDVGKVDPGIFISSIIPGGPAEKAKKIKPGGQILALNRISLEGFTFDMAVRMIQNSPDNIELIISQSKGVCGNTSSEEKNSTANSGVCSTDSLSNGHQGSLSSHTQDRERNIEELEMAQTQSVMPGLSPQLSALPLKGAGSSCPPSPSETNASEIYFVELVKEDGTLGFSVTGGINTSVFCGGIYVKSIVPGGPAAKEGRILQGDRLLQVDGVSLCGLTHKQAVQCLKGSGQVARLVLERRGPRIAQHCPSANDRMGEECTAVSLATVLPGRPASSVSATDGPKFEVKLKKNASGLGFSFVQMESEHRGHLKSDLVMIKRLFPGQPAEENGAMAVGDLILAVNGRSTEGLDFQEVLHLLRGASQEVTLLLCRPPPGALPEMDQGWQTPVLAADKEFSRAACTDLEQSPSLDQGDSRRDSASPDTGEGLGLRPESFQQATQEAQWDQDTERPWATSLTDPRDSFPHLCRLHQEMEASTLATSLEKDLRQNCDSVCDIRRLGSPELYSDNEERDMHHPPGTPSPTSKDEVYLTINPSLADQLPCGECLEADSGTIPLPQFCSWSTFSQSLPPEVSHESESKWEDFEEAEDADEGPLSAVSRW", "length": 1389, "header": "tr|A0A3Q1MGA7-1|A0A3Q1MGA7_BOVIN Computationally mapped isoform of FERM and PDZ domain containing 2 OS=Bos taurus OX=9913 GN=FRMPD2 PE=4 SV=2 CANONICAL=F1N2X3-1" }, "locus": { "chromosome": "28", "start_pos": 42688265, "end_pos": 42588427, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000084601.2", "url": "https://www.ensembl.org/id/ENSBTAT00000084601.2" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000069575.2", "url": "https://www.ensembl.org/id/ENSBTAP00000069575.2" } ] } }, { "isoform_ac": "A0AAA9SX83-1", "url": "https://www.uniprot.org/uniprotkb/A0AAA9SX83/entry", "sequence": { "sequence": "MCVFAGMSPASVTLASALQVRGEALSEEDIWSLLSLATERLLEDLCDDSSNYVVCPWSVLLSATGSLSFQDHVSHIEAAPFKAPELLQGQSNDEQLGASQPLQLCQPLHSILLTMCEDQPGRRLPLQSVLEACQIHWEEAAVHPTSANLHVRQLVGLVLGTISEVERRAVEESSSGQRDRSHLLRNRLHQASCESQAAWALGCAHRCRVSERSTETQSSLEPGLNTSARGRCSLAVNSALPVQVPPDLQEGRRLSSASALPENSQPATPSQRGFLQRKGKFSRPEFVLMAGEAPVTLYLPGSIVTKRAKSYLALRDLCVVLLSGQCLEVKCDITSTVGAVFSAIASFASLGELTYFGLAYMKGKEFFFLDAETRLCKIAPEGWSEQPQKKSSPNAFVLFLRIKFFVSHYGLLQHSWTRHQFYLQLRKDILEEKLYCSDEMLLQLGVLALQAEFGSYPEEVENKAYFRVEDYIPASLIERMTALRAQVEVSEMHRLSPMLWGEDAELEFLRVAQQLPEYGVLVYQVLPEKTRLEGEMALGICAKGVIVYEVRNNSRIATLRFQWREIEKILAYRKKFIITSSVTGKKHTFVADSVKTCKYLLGLCCAQHGFNAQMSSPGVTSDSDKCVQMASLSLAHLAQSNQLTWIQRLSSSENALFIPGLEDAAGGLLRRSLDNFTMDTSKGTRAQGLRGSPCLGREQLERLCLIQKPTTCDLLSRQPAQSMRTGSRNNRRRSFIAEPDGEIVHVTLSRDPHRGFGFVINEGEDVGKVDPGIFISSIIPGGPAEKAKKIKPGGQILALNRISLEGFTFDMAVRMIQNSPDNIELIISQSKGVCGNTSSEEKNSTANSGVCSTDSLSNGHQGSLSSHTQDRERNIEELEMAQTQSVMPGLSPQLSALPLKGAGSSCPPSPSETNASEIYFVELVKEDGTLGFSVTGGINTSVFCGGIYVKSIVPGGPAAKEGRILQGDRLLQVDGVSLCGLTHKQAVQCLKGSGQVARLVLERRGPRIAQHCPSANDRMGEECTAVSLATVLPGRPASSVSATDGPKFEVKLKKNASGLGFSFVQMESEHRGHLKSDLVMIKRLFPGQPAEENGAMAVGDLILAVNGRSTEGLDFQEVLHLLRGASQEVTLLLCRPPPGALPEMDQGWQTPVLAADKEFSRAACTDLEQSPSLDQGDSRRDSASPDTGEGLGLRPESFQQATQEAQWDQDTERPWATSLTDPRDSFPHLCRLHQEMEASTLATSLEKDLRQNCDSVCDIRRLGRFSYSSSLTRLSTDIF", "length": 1279, "header": "tr|A0AAA9SX83-1|F1N2X3_BOVIN Computationally mapped isoform of FERM and PDZ domain containing 2 OS=Bos taurus OX=9913 GN=FRMPD2 PE=4 SV=1 CANONICAL=F1N2X3-1" }, "locus": { "chromosome": "28", "start_pos": 42653280, "end_pos": 42589978, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000099144.1", "url": "https://www.ensembl.org/id/ENSBTAT00000099144.1" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000087904.1", "url": "https://www.ensembl.org/id/ENSBTAP00000087904.1" } ] } }, { "isoform_ac": "F1N2X3-1", "url": "https://www.uniprot.org/uniprotkb/F1N2X3/entry", "sequence": { "sequence": "TQPLTQDAGMSPASVTLASALQVRGEALSEEDIWSLLSLATERLLEDLCDDSSNYVVCPWSVLLSATGSLSFQDHVSHIEAAPFKAPELLQGQSNDEQLGASQMHVYSLGMTLYWSAGFHVPSNQPLQLCQPLHSILLTMCEDQPGRRLPLQSVLEACQIHWEEAAVHPTSANLHVRQLVGLVLGTISEVERRAVEESSSGQRDRSHLLRNRLHQASCESQAAWALGCAHRCRVSERSTETQSSLEPGLNTSARGRCSLAVNSALPVQVPPDLQEGRRLSSASALPENSQPATPSQRGFLQRKGKFSRPEFVLMAGEAPVTLYLPGSIVTKRAKSYLALRDLCVVLLSGQCLEVKCDITSTVGAVFSAIASFASLGELTYFGLAYMKGKEFFFLDAETRLCKIAPEGWSEQPQKKSSPNAFVLFLRIKFFVSHYGLLQHSWTRHQFYLQLRKDILEEKLYCSDEMLLQLGVLALQAEFGSYPEEQVENKAYFRVEDYIPASLIERMTALRAQVEVSEMHRLSPMLWGEDAELEFLRVAQQLPEYGVLVYQVLPEKTRLEGEMALGICAKGVIVYEVRNNSRIATLRFQWREIEKILAYRKKFIITSSVTGKKHTFVADSVKTCKYLLGLCCAQHGFNAQMSSPGVTSDSDKCVQMASLSLAHLAQSNQLTWIQRLSSSENALFIPGLEDAAGGLLRRSLDNFTMDTSKGTRAQGLRGSPCLGREQLERLCLIQKPTTCDLLSRQPAQSMRTGSRNNRRRSFIAEPDGEIVHVTLSRDPHRGFGFVINEGEDVGKVDPGIFISSIIPGGPAEKAKKIKPGGQILALNRISLEGFTFDMAVRMIQNSPDNIELIISQSKGVCGNTSSEEKNSTANSGVCSTDSLSNGHQGSLSSHTQDRERNIEELEMAQTQSVMPGLSPQLSALPLKGAGSSCPPSPSETNASEIYFVELVKEDGTLGFSVTGGINTSVFCGGIYVKSIVPGGPAAKEGRILQGDRLLQVDGVSLCGLTHKQAVQCLKGSGQVARLVLERRGPRIAQHCPSANDRMGEECTAVSLATVLPGRPASSVSATDGPKFEVKLKKNASGLGFSFVQMESEHRGHLKSDLVMIKRLFPGQPAEENGAMAVGDLILAVNGRSTEGLDFQEVLHLLRGASQEVTLLLCRPPPGALPEMDQGWQTPVLAADKEFSRAACTDLEQSPSLDQGDSRRDSASPDTGEGLGLRPESFQQATQEAQWDQDTERPWATSLTDPRDSFPHLCRLHQEMEASTLATSLEKDLRQNCDSVCDIRRLGRFSYSSSLTRLSTDIF", "length": 1305, "header": "tr|F1N2X3-1|F1N2X3_BOVIN Isoform 1 of FERM and PDZ domain containing 2 OS=Bos taurus OX=9913 GN=FRMPD2 PE=4 SV=4 CANONICAL=F1N2X3-1" }, "locus": { "chromosome": "28", "start_pos": 42688265, "end_pos": 42589978, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000007319.7", "url": "https://www.ensembl.org/id/ENSBTAT00000007319.7" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000007319.7", "url": "https://www.ensembl.org/id/ENSBTAP00000007319.7" } ] } } ], "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "other", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 293, "start_aa": "Thr", "end_pos": 293, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr293", "evidence": [ { "id": "", "database": "GlyGen", "url": "https://data.glygen.org/" } ], "filter_code": "000000000000000010000.00000000001000.0.01000" } ], "phosphorylation": [], "glycation": [], "keywords": [ "glycoprotein", "glycoprotein_predicted" ], "publication": [], "pathway": [], "orthologs": [], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 5, "go_terms": [ { "name": "cytoplasm", "id": "GO:0005737", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005737", "evidence": [ { "database": "UniProtKB", "id": "F1N2X3", "url": "https://www.uniprot.org/uniprotkb/F1N2X3" } ], "pmid": "" }, { "name": "plasma membrane", "id": "GO:0005886", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005886", "evidence": [ { "database": "UniProtKB", "id": "F1N2X3", "url": "https://www.uniprot.org/uniprotkb/F1N2X3" } ], "pmid": "" }, { "name": "bicellular tight junction", "id": "GO:0005923", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005923", "evidence": [ { "database": "UniProtKB", "id": "F1N2X3", "url": "https://www.uniprot.org/uniprotkb/F1N2X3" } ], "pmid": "" }, { "name": "basolateral plasma membrane", "id": "GO:0016323", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016323", "evidence": [ { "database": "UniProtKB", "id": "F1N2X3", "url": "https://www.uniprot.org/uniprotkb/F1N2X3" } ], "pmid": "" }, { "name": "apical part of cell", "id": "GO:0045177", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0045177", "evidence": [ { "database": "UniProtKB", "id": "F1N2X3", "url": "https://www.uniprot.org/uniprotkb/F1N2X3" } ], "pmid": "" } ] }, { "name": "Molecular Function", "total": 1, "go_terms": [ { "name": "1-phosphatidylinositol binding", "id": "GO:0005545", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005545", "evidence": [ { "database": "UniProtKB", "id": "F1N2X3", "url": "https://www.uniprot.org/uniprotkb/F1N2X3" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 1, "go_terms": [ { "name": "bicellular tight junction assembly", "id": "GO:0070830", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0070830", "evidence": [ { "database": "UniProtKB", "id": "F1N2X3", "url": "https://www.uniprot.org/uniprotkb/F1N2X3" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 1081, "end_pos": 1083, "annotation": "n_glycosylation_sequon" }, { "start_pos": 250, "end_pos": 252, "annotation": "n_glycosylation_sequon" }, { "start_pos": 578, "end_pos": 580, "annotation": "n_glycosylation_sequon" }, { "start_pos": 701, "end_pos": 703, "annotation": "n_glycosylation_sequon" }, { "start_pos": 862, "end_pos": 864, "annotation": "n_glycosylation_sequon" }, { "start_pos": 869, "end_pos": 871, "annotation": "n_glycosylation_sequon" }, { "start_pos": 940, "end_pos": 942, "annotation": "n_glycosylation_sequon" }, { "start_pos": 965, "end_pos": 967, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "F1N2X3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1N2X3" }, { "id": "PS50057", "database": "PROSITE", "url": "https://prosite.expasy.org/PS50057" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "FERM", "eco_id": "ECO_0000259", "start_pos": 340, "end_pos": 641, "start_aa": "Arg", "end_aa": "Ser", "glycosite_overlap": [] }, { "evidence": [ { "id": "F1N2X3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1N2X3" }, { "id": "PS51377", "database": "PROSITE", "url": "https://prosite.expasy.org/PS51377" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "KIND", "eco_id": "ECO_0000259", "start_pos": 15, "end_pos": 197, "start_aa": "Val", "end_aa": "Glu", "glycosite_overlap": [] }, { "evidence": [ { "id": "F1N2X3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1N2X3" }, { "id": "PS50106", "database": "PROSITE", "url": 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"count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { 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[ "Genome Annotation" ] }, { "id": "IPR003903", "url": "https://www.ebi.ac.uk/interpro/entry/IPR003903", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR008942", "url": "https://www.ebi.ac.uk/interpro/entry/IPR008942", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR013809", "url": "https://www.ebi.ac.uk/interpro/entry/IPR013809", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "bta:538660", "url": "https://www.genome.jp/dbget-bin/www_bget?bta:538660", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "SGTHESA", "url": "https://omabrowser.org/oma/group/SGTHESA/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "A0A3Q1M4S2", "url": "https://www.orthodb.org/?gene=A0A3Q1M4S2", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR12276", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR12276", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR12276:SF16", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR12276:SF16", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF01417", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF01417", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF02809", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF02809", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "NP_001039899", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001039899", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A3Q1M4S2", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1M4S2", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A3Q1M4S2-1", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1M4S2-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "F1N4F8", "url": "https://www.uniprot.org/uniprotkb/F1N4F8", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "F1N4F8-1", "url": "https://www.uniprot.org/uniprotkb/F1N4F8-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MTTSALRRQVKNIVHNYSEAEIKVREATSNDPWGPPSSLMSEIADLTFNTVAFAEVMGMLWRRLNDSGKNWRHVYKALTLLDYLLKTGSERVAHQCRENLYTIQTLKDFQYVDRDGKDQGVNVREKVKQVMALLKDEERLRQERTHALKTKERMALEGTGISSGQLGLSRARGSPSSYNSSSSSPRYTSDLEQARPQTSGEEELQLQLALAMSREEAEKEVRSWQGDDSPVANGAGAGAHRRWDREPERAEREEEKLKTSQSSSLDLVDIFASASTLPSTHCSADPWDIPGLRPNTEPSGSSWGPSADPWSPVPSGSIMSQSQPWDLPPVLSSSEPWGRTPVLPAGPPTTDFWAQNSPHHKLPNNGAKPWGNLVETFNTPALDGSSTFDPLAKPPVSTETKEGLECTQALPSGKPSSPVELDLFGDHTPSVKQNGTKEPDAFDLDVLGEALAQSSRDTPARRTPESFLGPSASSLVNLDSLVKVPQAVKTRNPFLTGLSTPSPTNPFGGGDQSRRTLNQMRTGSPALSLTAGGPIGAPFGSMTYSASLPLPLSSVPAGVTLPASVSVFPQARAFTPPPSGSLPQPLLPTSGSAGPLNQTPLTDTNPFL", "length": 608, "header": "tr|F1N4F8-1|F1N4F8_BOVIN Isoform 1 of Epsin 3 OS=Bos taurus OX=9913 GN=EPN3 PE=3 SV=3 CANONICAL=F1N4F8-1" }, "isoforms": [ { "isoform_ac": "A0A3Q1M4S2-1", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1M4S2/entry", "sequence": { "sequence": "MTTSALRRQVKNIVHNYSEAEIKVREATSNDPWGPPSSLMSEIADLTFNTVAFAEVMGMLWRRLNDSGKNWRHVYKALTLLDYLLKTGSERVAHQCRENLYTIQTLKDFQYVDRDGKDQGVNVREKVKQVMALLKDEERLRQERTHALKTKERMALEGTGISSGQLGLSRARGSPSSYNSSSSSPRYTSDLEQARPQTSGEEELQLQLALAMSREEAEKPVPPTSHRDEDLQLQLALHLSRQEQEKEVRSWQGDDSPVANGAGAGAHRRWDREPERAEREEEKLKTSQSSSLDLVDIFASASTLPSTHCSADPWDIPGLRPNTEPSGSSWGPSADPWSPVPSGSIMSQSQPWDLPPVLSSSEPWGRTPVLPAGPPTTDFWAQNSPHHKLPNNGAKPWGNLVETFNTPALDGSSTFDPLAKPPVSTETKEGLECTQALPSGKPSSPVELDLFGDHTPSVKQNGTKEPDAFDLDVLGEALAQSSRDTPARRTPESFLGPSASSLVNLDSLVKVPQAVKTRNPFLTGLSTPSPTNPFGGGDQSRRTLNQMRTGSPALSLTAGGPIGAPFGSMTYSASLPLPLSSVPAGVTLPASVSVFPQARAFTPPPSGSLPQPLLPTSGSAGPLNQTPLTDTNPFL", "length": 635, "header": "tr|A0A3Q1M4S2-1|A0A3Q1M4S2_BOVIN Computationally mapped isoform of Epsin 3 OS=Bos taurus OX=9913 GN=EPN3 PE=3 SV=1 CANONICAL=F1N4F8-1" }, "locus": { "chromosome": "19", "start_pos": 36189017, "end_pos": 36183167, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000075862.2", "url": "https://www.ensembl.org/id/ENSBTAT00000075862.2" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000063264.1", "url": "https://www.ensembl.org/id/ENSBTAP00000063264.1" } ] } }, { "isoform_ac": "F1N4F8-1", "url": "https://www.uniprot.org/uniprotkb/F1N4F8/entry", "sequence": { "sequence": "MTTSALRRQVKNIVHNYSEAEIKVREATSNDPWGPPSSLMSEIADLTFNTVAFAEVMGMLWRRLNDSGKNWRHVYKALTLLDYLLKTGSERVAHQCRENLYTIQTLKDFQYVDRDGKDQGVNVREKVKQVMALLKDEERLRQERTHALKTKERMALEGTGISSGQLGLSRARGSPSSYNSSSSSPRYTSDLEQARPQTSGEEELQLQLALAMSREEAEKEVRSWQGDDSPVANGAGAGAHRRWDREPERAEREEEKLKTSQSSSLDLVDIFASASTLPSTHCSADPWDIPGLRPNTEPSGSSWGPSADPWSPVPSGSIMSQSQPWDLPPVLSSSEPWGRTPVLPAGPPTTDFWAQNSPHHKLPNNGAKPWGNLVETFNTPALDGSSTFDPLAKPPVSTETKEGLECTQALPSGKPSSPVELDLFGDHTPSVKQNGTKEPDAFDLDVLGEALAQSSRDTPARRTPESFLGPSASSLVNLDSLVKVPQAVKTRNPFLTGLSTPSPTNPFGGGDQSRRTLNQMRTGSPALSLTAGGPIGAPFGSMTYSASLPLPLSSVPAGVTLPASVSVFPQARAFTPPPSGSLPQPLLPTSGSAGPLNQTPLTDTNPFL", "length": 608, "header": "tr|F1N4F8-1|F1N4F8_BOVIN Isoform 1 of Epsin 3 OS=Bos taurus OX=9913 GN=EPN3 PE=3 SV=3 CANONICAL=F1N4F8-1" }, "locus": { "chromosome": "19", "start_pos": 36189017, "end_pos": 36183167, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000043309.5", "url": "https://www.ensembl.org/id/ENSBTAT00000043309.5" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000040887.4", "url": "https://www.ensembl.org/id/ENSBTAP00000040887.4" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [ { "id": "bta:538660", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?bta:538660", "resource": "KEGG Pathway" } ], "orthologs": [ { "uniprot_canonical_ac": "A0A8V1APK7-1", "protein_name": "Epsin 3", "gene_name": "EPN3", "tax_id": 9031, "organism": "Gallus gallus", "sequence": { "sequence": "MTTSALRRQVKNIVHNYSEAEIKVREATSNDPWGPPSSLMSEIADLTFNTVAFAEVMGMIWRRLNDSGKNWRHVYKALTLLDYLIKTGSEKVTHQCRENLYTIQTLKDFQYVDRDGKDQGINIREKVKQVMALLKDEERLKQERAHALQTKERMALEGMGSGSHQSTYGRRASPYGDDYGRTRGSPSSFNSSSSSPRFASDLEQARPQTTGEEELQLQLALAMSREEAEKEVRAWQGENSLLQRALEETAQGGEEEEEEDKMKKSQSSILELADIFGPAPAPSGHTSADPWDMPDMKPKAEPAAWTGTADPWVPVLSSSGEPVPQAGTTSQQTAAGPWDFPPASADPWGKAPASSGFSPADPWTATSPPAQGSGTTPATDPWAAVAEPNPNPAAGGDAFDLFAKQPEAAEQPEMEHSQPPSSVKSSSPAELDPFGDLFPGTKQDAAKSFDLANLADSLPESCKERKDCKTPEAFLGPAASSLVNLDSLVAPPQAAKTRNPFLSGLSTPSPTNPFSLAEQPKPTLNQMRTGSPVPGLPAALPANAMTYSTSLPLPLSSVPAALPASASAFPQAGAGPFPELPGALPQPLLPLSGPPAPQGGLNPFL", "length": 605 }, "evidence": [ { "id": "F1N4F8", "url": "https://omabrowser.org/oma/group/F1N4F8/", "database": "OMA" } ], "glygen_name": "Chicken", "common_name": "Chicken" }, { "uniprot_canonical_ac": "Q4V882-1", "protein_name": "Epsin-3", "gene_name": "Epn3", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MTTSALRRQVKNIVHNYSEAEIKVREATSNDPWGPPSSLMSEIADLTFNTVAFAEVMGMVWRRLNDSGKNWRHVYKALTLLDYLLKTGSERVAHQCRENLYTIQTLKDFQYIDRDGKDQGVNVREKVKQVMALLKDEERLRQERTHALKTKERMALEGMGIGSGQLGFSRRSRGSPSSYTSASSSPRYASDLEQARPQTSGEEELQLQLALAMSREEAEKGGRSWKGDDFPVANGAEPAGQRRRDREPEREERKEEEKLKTSQSSILDLADVFAPAPALPSTHCSADPWDIPGLRPNTEPSGSSWGPSADPWSPVPSGNALSRSQPWDLLPTLSSSEPWGRTPVLPSGPPITDPWAPSSPTPKLPSTGVDPWGASVETSNTSALGGASPFDPFAKPLESTEPMESRDSAQALPKGKSPSPVELDPFGDSSPSCKQNGVKETEALDLGVLGEALTQQPGKEARPCRTPESFLGPSASSLVNLDSLVKAPLAARTRNPFLTGLSAPSPTNPFGAGEQGRPTLNQMRTGSPALGLPPGGPVGVPLGSMTYSASLPLPLSSVPVGATLPASVSVFPQAGAFAPPPASLPQPLLPTSDPVGPLPPQAGTNPFL", "length": 608 }, "evidence": [ { "id": "F1N4F8", "url": "https://omabrowser.org/oma/group/F1N4F8/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "Q91W69-1", "protein_name": "Epsin-3", "gene_name": "Epn3", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MTTSALRRQVKNIVHNYSEAEIKVREATSNDPWGPPSSLMSEIADLTFNTVAFAEVMGMVWRRLNDSGKNWRHVYKALTLLDYLLKTGSERVAHQCRENLYTIQTLKDFQYIDRDGKDQGVNVREKVKQVMALLKDEERLRQERTHALKTKERMALEGMGIGSGQLGYSRRSRGSPSSYTSASSSPRYASDLEQARPQTSGEEELQLQLALAMSREEAERPVPPASHRDEDLQLQLALSLSRQEHEKGVRSWKGDDSPVANGAEPAGQRRQRDREPEREERKEEEKLKTSQSSILDLADIFAPAPALPSTHCSADPWDIPGLRPNTEPSGSSWGPSADPWSPVPSGNALSRSQPWDLLPTLSSSEPWGRTPVLPSGPPIADPWAPSSPTRKLPSTGADPWGASMETSDTSALGGASPFDPFAKPLESTEPKESRDSAQALPTGKSPSTVELDPFGDSSPSCKQNGMKEPEALDLGVLGEALPQQPGKEARPCRTPESFLGPSASSLVNLDSLVKAPLAARTRNPFLTGLGVPSPTNPFGAGDQGRPTLNQMRTGSPALGLPPGGPVGAPVGSMTYSASLPLPLSSVPVGATLPASVSVFPQAGAFAPPPASLPQPLLPTSGPMGPLPPQAGTNPFL", "length": 636 }, "evidence": [ { "id": "F1N4F8", "url": "https://omabrowser.org/oma/group/F1N4F8/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q9H201-1", "protein_name": "Epsin-3", "gene_name": "EPN3", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MTTSALRRQVKNIVHNYSEAEIKVREATSNDPWGPPSSLMSEIADLTFNTVAFTEVMGMLWRRLNDSGKNWRHVYKALTLLDYLLKTGSERVAHQCRENLYTIQTLKDFQYIDRDGKDQGVNVREKVKQVMALLKDEERLRQERTHALKTKERMALEGIGIGSGQLGFSRRYGEDYSRSRGSPSSYNSSSSSPRYTSDLEQARPQTSGEEELQLQLALAMSREEAEKPVPPASHRDEDLQLQLALRLSRQEHEKEVRSWQGDGSPMANGAGAVVHHQRDREPEREERKEEEKLKTSQSSILDLADIFVPALAPPSTHCSADPWDIPGFRPNTEASGSSWGPSADPWSPIPSGTVLSRSQPWDLTPMLSSSEPWGRTPVLPAGPPTTDPWALNSPHHKLPSTGADPWGASLETSDTPGGASTFDPFAKPPESTETKEGLEQALPSGKPSSPVELDLFGDPSPSSKQNGTKEPDALDLGILGEALTQPSKEARACRTPESFLGPSASSLVNLDSLVKAPQVAKTRNPFLTGLSAPSPTNPFGAGEPGRPTLNQMRTGSPALGLAGGPVGAPLGSMTYSASLPLPLSSVPAGLTLPASVSVFPQAGAFAPQPLLPTPSSAGPRPPPPQTGTNPFL", "length": 632 }, "evidence": [ { "id": "F1N4F8", "url": "https://omabrowser.org/oma/group/F1N4F8/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" } ], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 8, "go_terms": [ { "name": "clathrin vesicle coat", "id": "GO:0030125", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030125", "evidence": [ { "database": "UniProtKB", "id": "F1N4F8", "url": "https://www.uniprot.org/uniprotkb/F1N4F8" } ], "pmid": "" }, { "name": "nucleus", "id": "GO:0005634", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005634", "evidence": [ { "database": "UniProtKB", "id": "F1N4F8", "url": "https://www.uniprot.org/uniprotkb/F1N4F8" } ], "pmid": "" }, { "name": "endosome", "id": "GO:0005768", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005768", "evidence": [ { "database": "UniProtKB", "id": "F1N4F8", "url": "https://www.uniprot.org/uniprotkb/F1N4F8" } ], "pmid": "" }, { "name": "plasma membrane", "id": "GO:0005886", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005886", "evidence": [ { "database": "UniProtKB", "id": "F1N4F8", "url": "https://www.uniprot.org/uniprotkb/F1N4F8" } ], "pmid": "" }, { "name": "clathrin-coated pit", "id": "GO:0005905", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005905", "evidence": [ { "database": "UniProtKB", "id": "F1N4F8", "url": "https://www.uniprot.org/uniprotkb/F1N4F8" } ], "pmid": "" }, { "name": "perinuclear region of cytoplasm", "id": "GO:0048471", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0048471", "evidence": [ { "database": "UniProtKB", "id": "F1N4F8", "url": "https://www.uniprot.org/uniprotkb/F1N4F8" } ], "pmid": "" }, { "name": "cytoplasmic side of plasma membrane", "id": "GO:0009898", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0009898", "evidence": [ { "database": "UniProtKB", "id": "F1N4F8", "url": "https://www.uniprot.org/uniprotkb/F1N4F8" } ], "pmid": "" }, { "name": "cytoplasm", "id": "GO:0005737", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005737", "evidence": [ { "database": "UniProtKB", "id": "F1N4F8", "url": "https://www.uniprot.org/uniprotkb/F1N4F8" } ], "pmid": "" } ] }, { "name": "Molecular Function", "total": 4, "go_terms": [ { "name": "phospholipid binding", "id": "GO:0005543", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005543", "evidence": [ { "database": "UniProtKB", "id": "F1N4F8", "url": "https://www.uniprot.org/uniprotkb/F1N4F8" } ], "pmid": "" }, { "name": "clathrin binding", "id": "GO:0030276", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030276", "evidence": [ { "database": "UniProtKB", "id": "F1N4F8", "url": "https://www.uniprot.org/uniprotkb/F1N4F8" } ], "pmid": "" }, { "name": "EH domain binding", "id": "GO:1990175", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:1990175", "evidence": [ { "database": "UniProtKB", "id": "F1N4F8", "url": "https://www.uniprot.org/uniprotkb/F1N4F8" } ], "pmid": "" }, { "name": "lipid binding", "id": "GO:0008289", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008289", "evidence": [ { "database": "UniProtKB", "id": "F1N4F8", "url": "https://www.uniprot.org/uniprotkb/F1N4F8" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 1, "go_terms": [ { "name": "endocytosis", "id": "GO:0006897", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006897", "evidence": [ { "database": "UniProtKB", "id": "F1N4F8", "url": "https://www.uniprot.org/uniprotkb/F1N4F8" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 16, "end_pos": 18, "annotation": "n_glycosylation_sequon" }, { "start_pos": 179, "end_pos": 181, "annotation": "n_glycosylation_sequon" }, { "start_pos": 434, "end_pos": 436, "annotation": "n_glycosylation_sequon" }, { "start_pos": 597, "end_pos": 599, "annotation": "n_glycosylation_sequon" }, { "start_pos": 65, "end_pos": 67, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "F1N4F8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1N4F8" }, { "id": "PS50942", "database": "PROSITE", "url": "https://prosite.expasy.org/PS50942" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "ENTH", "eco_id": "ECO_0000259", "start_pos": 12, "end_pos": 144, "start_aa": "Asn", "end_aa": "Arg", "glycosite_overlap": [] } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" }, { "name": "homologset.oma", "label": "OMA Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 16, "end_pos": 18 }, { "start_pos": 179, "end_pos": 181 }, { "start_pos": 434, "end_pos": 436 }, { "start_pos": 597, "end_pos": 599 }, { "start_pos": 65, "end_pos": 67 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": 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], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "Metaxin glutathione S-transferase", "eco_id": "ECO_0000259", "start_pos": 188, "end_pos": 250, "start_aa": "Asp", "end_aa": "Ile", "glycosite_overlap": [] }, { "evidence": [ { "id": "F6RBN9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F6RBN9" }, { "id": "PF10568", "database": "Pfam", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF10568" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "Mitochondrial outer membrane transport complex Sam37/metaxin N-terminal", "eco_id": "ECO_0000259", "start_pos": 42, "end_pos": 163, "start_aa": "Ser", "end_aa": "Gln", "glycosite_overlap": [] } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], 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Recruits AP-2 and attaches clathrin triskelions to the cytoplasmic side of plasma membrane leading to clathrin-coated vesicles (CCVs) assembly. Furthermore, regulates clathrin-coated vesicle size and maturation by directly sensing and driving membrane curvature. In addition to binding to clathrin, mediates the endocytosis of small R-SNARES (Soluble NSF Attachment Protein REceptors) between plasma membranes and endosomes including VAMP2, VAMP3, VAMP4, VAMP7 or VAMP8. In turn, PICALM-dependent SNARE endocytosis is required for the formation and maturation of autophagic precursors. 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"categories": [ "Protein Classification" ] }, { "id": "F1N605", "url": "https://www.orthodb.org/?gene=F1N605", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR22951", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR22951", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR22951:SF16", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR22951:SF16", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF07651", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF07651", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "XP_024842851", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_024842851", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A3Q1LJ93", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1LJ93", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A3Q1LJ93-1", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1LJ93-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A3Q1LVY5", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1LVY5", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A3Q1LVY5-1", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1LVY5-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A3Q1N8I6", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1N8I6", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A3Q1N8I6-1", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1N8I6-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0AAA9TY38", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TY38", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0AAA9TY38-1", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TY38-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "F1N605", "url": "https://www.uniprot.org/uniprotkb/F1N605", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "F1N605-1", "url": "https://www.uniprot.org/uniprotkb/F1N605-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MSGQSLTDRITAAQHSVTGSAVSKTVCKATTHEIMGPKKKHLDYLIQCTNEMNVNIPQLADSLFERTTNSSWVVVFKSLITTHHLMVYGNERFIQYLASRNTLFNLSNFLDKSGLQGYDMSTFIRRYSRYLNEKAVSYRQVAFDFTKVKRGADGVMRTMNTEKLLKTVPIIQNQMDALLDFNVNSNELTNGVINAAFMLLFKDAIRLFAAYNEGIINLLEKYFDMKKNQCKEGLDIYKKFLTRMTRISEFLKVAEQVGIDRGDIPDLSQAPSSLLDALEQHLASLEGKKIKDSTAASRATTLSNAVSSLASTGLSLTKVDEREKQAALEEEQARLKALKEQRLKELAKKPHTSLTTAASPVSTSAGSVMTAPAIDIFSTPSSSNSTSKLPNDLLDLQQPTFHPPVLSMSTASQVASTWGDPFSATVDAVDDAIPSLNPFLTKSSGDVHLPISSDVSTFTTRTPTHEMFVGFTPSPVAQPHPSAGLNVDFESVFGNKSTNITVDSGGFDELGGLLKPTVASQNQSLPVAKLPPNKLVSDDLDSSLANLVGNLGIGNGTTKNDVNWSQPGEKKLTGGSNWQPKVAPTTAWNAATMNGMHFPQYAPPVMAYPATTPTGMIGYGIPPQMGSVPVMTQPSLIYSQPVMRPPNPFGPVSGAQLSAASSPSSHSPHRASGKDPFAELSLEDFL", "length": 686, "header": "tr|F1N605-1|F1N605_BOVIN Isoform 1 of Phosphatidylinositol-binding clathrin assembly protein OS=Bos taurus OX=9913 GN=PICALM PE=1 SV=3 CANONICAL=F1N605-1" }, "isoforms": [ { "isoform_ac": "A0A3Q1LJ93-1", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1LJ93/entry", "sequence": { "sequence": "MNVNIPQLADSLFERTTNSSWVVVFKSLITTHHLMVYGNERFIQYLASRNTLFNLSNFLDKSGLQGYDMSTFIRRYSRYLNEKAVSYRQVAFDFTKVKRGADGVMRTMNTEKLLKTVPIIQNQMDALLDFNVNSNELTNGVINAAFMLLFKDAIRLFAAYNEGIINLLEKYFDMKKNQCKEGLDIYKKFLTRMTRISEFLKVAEQVGIDRGDIPDLSQAPSSLLDALEQHLASLEGKKIKDSTAASRATTLSNAVSSLASTGLSLTKVDEREKQAALEEEQARLKALKEQRLKELAKKPHTSLTTAASPVSTSAGSVMTAPAIDIFSTPSSSNSTSKLPNDLLDLQQPTFHPPVLSMSTASQVASTWGDPFSATVDAVDDAIPSLNPFLTKSSGDVHLPISSDVSTFTTRTPTHEMFVDTFCGTQAYRNTTFMCHEPSTVAGLFGGFTPSPVAQPHPSAGLNVDFESVFGNKSTNITVDSGGFDELGGLLKPTVASQNQSLPVAKLPPNKLVSDDLDSSLANLVGNLGIGNGTTKNDVNWSQPGEKKLTGGSNWQPKVAPTTAWNAATMNGMHFPQYAPPVMAYPATTPTGMIGYGIPPQMGSVPVMTQPSLIYSQPVMRPPNPFGPVSGAQLSAASSPSSHSPHRASGKDPFAELSLEDFL", "length": 662, "header": "tr|A0A3Q1LJ93-1|A0A3Q1LJ93_BOVIN Computationally mapped isoform of Phosphatidylinositol binding clathrin assembly protein OS=Bos taurus OX=9913 GN=PICALM PE=1 SV=1 CANONICAL=F1N605-1" }, "locus": { "chromosome": "29", "start_pos": 9617972, "end_pos": 9552598, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000079768.3", "url": "https://www.ensembl.org/id/ENSBTAT00000079768.3" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000059400.1", "url": "https://www.ensembl.org/id/ENSBTAP00000059400.1" } ] } }, { "isoform_ac": "A0A3Q1LVY5-1", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1LVY5/entry", "sequence": { "sequence": "MSGQSLTDRITAAQHSVTGSAVSKTVCKATTHEIMGPKKKHLDYLIQCTNEMNVNIPQLADSLFERTTNSSWVVVFKSLITTHHLMVYGNERFIQYLASRNTLFNLSNFLDKSGLQGYDMSTFIRRYSRYLNEKAVSYRQVAFDFTKVKRGADGVMRTMNTEKLLKTVPIIQNQMDALLDFNVNSNELTNGVINAAFMLLFKDAIRLFAAYNEGIINLLEKYFDMKKNQCKEGLDIYKKFLTRMTRISEFLKVAEQVGIDRGDIPDLSQAPSSLLDALEQHLASLEGKKIKDSTAASRATTLSNAVSSLASTGLSLTKVDEREKQAALEEEQARLKALKEQRLKELAKKPHTSLTTAASPVSTSAGSVMTAPAIDIFSTPSSSNSTSKLPNDLLDLQQPTFHPPVLSMSTASQVASTWGDPFSATVDAVDDAIPSLNPFLTKSSGDVHLPISSDVSTFTTRTPTHEMFVGFTPSPVAQPHPSAGLNVDFESVFGNKSTNITVDSGGFDELGGLLKPTVASQNQSLPVAKLPPNKLVSDDLDSSLANLVGNLGIGNGTTKNDVNWSQPGEKKLTGGSNWQPKVAPTTAWNAATMAPPVMAYPATTPTGMIGYGIPPQMGSVPVMTQPSLIYSQPVMRPPNPFGPVSGAQIQFM", "length": 652, "header": "tr|A0A3Q1LVY5-1|A0A3Q1LVY5_BOVIN Computationally mapped isoform of Phosphatidylinositol-binding clathrin assembly protein OS=Bos taurus OX=9913 GN=PICALM PE=1 SV=2 CANONICAL=F1N605-1" }, "locus": { "chromosome": "29", "start_pos": 9619243, "end_pos": 9519983, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000077265.2", "url": "https://www.ensembl.org/id/ENSBTAT00000077265.2" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000061348.2", "url": "https://www.ensembl.org/id/ENSBTAP00000061348.2" } ] } }, { "isoform_ac": "A0A3Q1N8I6-1", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1N8I6/entry", "sequence": { "sequence": "MSGQSLTDRITAAQHSVTGSAVSKTVCKATTHEIMGPKKKHLDYLIQCTNEMNVNIPQLADSLFERTTNSSWVVVFKSLITTHHLMVYGNERFIQYLASRNTLFNLSNFLDKSGLQGYDMSTFIRRYSRYLNEKAVSYRQVAFDFTKVKRGADGVMRTMNTEKLLKTVPIIQNQMDALLDFNVNSNELTNGVINAAFMLLFKDAIRLFAAYNEGIINLLEKYFDMKKNQCKEGLDIYKKFLTRMTRISEFLKVAEQVGIDRGDIPDLSQAPSSLLDALEQHLASLEGKKIKDSTAASRATTLSNAVSSLASTGLSLTKVDEREKQAALEEEQARLKALKEQRLKELAKKPHTSLTTAASPVSTSAGSVMTAPAIDIFSTPSSSNSTSKLPNDLLDLQQPTFHPPVLSMSTASQVASTWGGFTPSPVAQPHPSAGLNVDFESVFGNKSTNITVDSGGFDELGGLLKPTVASQNQSLPVAKLPPNKLVSDDLDSSLANLVGNLGIGNGTTKNDVNWSQPGEKKLTGGSNWQPKVAPTTAWNAATMAPPVMAYPATTPTGMIGYGIPPQMGSVPVMTQPSLIYSQPVMRPPNPFGPVSGAQIQFM", "length": 602, "header": "tr|A0A3Q1N8I6-1|F1N605_BOVIN Computationally mapped isoform of Phosphatidylinositol-binding clathrin assembly protein OS=Bos taurus OX=9913 GN=PICALM PE=1 SV=2 CANONICAL=F1N605-1" }, "locus": { "chromosome": "29", "start_pos": 9619243, "end_pos": 9519983, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000072874.3", "url": "https://www.ensembl.org/id/ENSBTAT00000072874.3" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000067353.2", "url": "https://www.ensembl.org/id/ENSBTAP00000067353.2" } ] } }, { "isoform_ac": "A0AAA9TY38-1", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TY38/entry", "sequence": { "sequence": "MSGQSLTDRITAAQHSVTGSAVSKTVCKATTHEIMGPKKKHLDYLIQCTNEMNVNIPQLADSLFERTTNSSWVVVFKSLITTHHLMVYGNEDMTCLHLLGGIVGI", "length": 105, "header": "tr|A0AAA9TY38-1|A0AAA9TY38_BOVIN Computationally mapped isoform of Phosphatidylinositol binding clathrin assembly protein OS=Bos taurus OX=9913 GN=PICALM PE=1 SV=1 CANONICAL=F1N605-1" }, "locus": { "chromosome": "29", "start_pos": 9559727, "end_pos": 9519983, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000121785.2", "url": "https://www.ensembl.org/id/ENSBTAT00000121785.2" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000102421.1", "url": "https://www.ensembl.org/id/ENSBTAP00000102421.1" } ] } }, { "isoform_ac": "F1N605-1", "url": "https://www.uniprot.org/uniprotkb/F1N605/entry", "sequence": { "sequence": "MSGQSLTDRITAAQHSVTGSAVSKTVCKATTHEIMGPKKKHLDYLIQCTNEMNVNIPQLADSLFERTTNSSWVVVFKSLITTHHLMVYGNERFIQYLASRNTLFNLSNFLDKSGLQGYDMSTFIRRYSRYLNEKAVSYRQVAFDFTKVKRGADGVMRTMNTEKLLKTVPIIQNQMDALLDFNVNSNELTNGVINAAFMLLFKDAIRLFAAYNEGIINLLEKYFDMKKNQCKEGLDIYKKFLTRMTRISEFLKVAEQVGIDRGDIPDLSQAPSSLLDALEQHLASLEGKKIKDSTAASRATTLSNAVSSLASTGLSLTKVDEREKQAALEEEQARLKALKEQRLKELAKKPHTSLTTAASPVSTSAGSVMTAPAIDIFSTPSSSNSTSKLPNDLLDLQQPTFHPPVLSMSTASQVASTWGDPFSATVDAVDDAIPSLNPFLTKSSGDVHLPISSDVSTFTTRTPTHEMFVGFTPSPVAQPHPSAGLNVDFESVFGNKSTNITVDSGGFDELGGLLKPTVASQNQSLPVAKLPPNKLVSDDLDSSLANLVGNLGIGNGTTKNDVNWSQPGEKKLTGGSNWQPKVAPTTAWNAATMNGMHFPQYAPPVMAYPATTPTGMIGYGIPPQMGSVPVMTQPSLIYSQPVMRPPNPFGPVSGAQLSAASSPSSHSPHRASGKDPFAELSLEDFL", "length": 686, "header": "tr|F1N605-1|F1N605_BOVIN Isoform 1 of Phosphatidylinositol-binding clathrin assembly protein OS=Bos taurus OX=9913 GN=PICALM PE=1 SV=3 CANONICAL=F1N605-1" }, "locus": { "chromosome": "29", "start_pos": 9617972, "end_pos": 9519983, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000002170.8", "url": "https://www.ensembl.org/id/ENSBTAT00000002170.8" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000002170.7", "url": "https://www.ensembl.org/id/ENSBTAP00000002170.7" } ] } } ], "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "other", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 585, "start_aa": "Thr", "end_pos": 585, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr585", "evidence": [ { "id": "", "database": "GlyGen", "url": "https://data.glygen.org/" } ], "filter_code": "000000000000000010000.00000000001000.0.01000" } ], "phosphorylation": [], "glycation": [], "keywords": [ "glycoprotein", "glycoprotein_predicted" ], "publication": [], "pathway": [], "orthologs": [], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 12, "go_terms": [ { "name": "Golgi apparatus", "id": "GO:0005794", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005794", "evidence": [ { "database": "UniProtKB", "id": "F1N605", "url": "https://www.uniprot.org/uniprotkb/F1N605" } ], "pmid": "" }, { "name": "clathrin-coated pit", "id": "GO:0005905", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005905", "evidence": [ { "database": "UniProtKB", "id": "F1N605", "url": "https://www.uniprot.org/uniprotkb/F1N605" } ], "pmid": "" }, { "name": "clathrin-coated vesicle", "id": "GO:0030136", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030136", "evidence": [ { "database": "UniProtKB", "id": "F1N605", "url": "https://www.uniprot.org/uniprotkb/F1N605" } ], "pmid": "" }, { "name": "nucleus", "id": "GO:0005634", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005634", "evidence": [ { "database": "UniProtKB", "id": "F1N605", "url": "https://www.uniprot.org/uniprotkb/F1N605" } ], "pmid": "" }, { "name": "plasma membrane", "id": "GO:0005886", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005886", "evidence": [ { "database": "UniProtKB", "id": "F1N605", "url": "https://www.uniprot.org/uniprotkb/F1N605" } ], "pmid": "" }, { "name": "early endosome", "id": "GO:0005769", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005769", "evidence": [ { "database": "UniProtKB", "id": "F1N605", "url": "https://www.uniprot.org/uniprotkb/F1N605" } ], "pmid": "" }, { "name": "cell surface", "id": "GO:0009986", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0009986", "evidence": [ { "database": "UniProtKB", "id": "F1N605", "url": "https://www.uniprot.org/uniprotkb/F1N605" } ], "pmid": "" }, { "name": "neuronal cell body", "id": "GO:0043025", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0043025", "evidence": [ { "database": "UniProtKB", "id": "F1N605", "url": "https://www.uniprot.org/uniprotkb/F1N605" } ], "pmid": "" }, { "name": "perinuclear region of cytoplasm", "id": "GO:0048471", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0048471", "evidence": [ { "database": "UniProtKB", "id": "F1N605", "url": "https://www.uniprot.org/uniprotkb/F1N605" } ], "pmid": "" }, { "name": "endosome to plasma membrane transport vesicle", "id": "GO:0070381", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0070381", "evidence": [ { "database": "UniProtKB", "id": "F1N605", "url": "https://www.uniprot.org/uniprotkb/F1N605" } ], "pmid": "" }, { "name": "neurofibrillary tangle", "id": "GO:0097418", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0097418", "evidence": [ { "database": "UniProtKB", "id": "F1N605", "url": "https://www.uniprot.org/uniprotkb/F1N605" } ], "pmid": "" }, { "name": "clathrin coat of coated pit", "id": "GO:0030132", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030132", "evidence": [ { "database": "UniProtKB", "id": "F1N605", "url": "https://www.uniprot.org/uniprotkb/F1N605" } ], "pmid": "" } ] }, { "name": "Molecular Function", "total": 8, "go_terms": [ { "name": "1-phosphatidylinositol binding", "id": "GO:0005545", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005545", "evidence": [ { "database": "UniProtKB", "id": "F1N605", "url": "https://www.uniprot.org/uniprotkb/F1N605" } ], "pmid": "" }, { "name": "clathrin binding", "id": "GO:0030276", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030276", "evidence": [ { "database": "UniProtKB", "id": "F1N605", "url": "https://www.uniprot.org/uniprotkb/F1N605" } ], "pmid": "" }, { "name": "phospholipid binding", "id": "GO:0005543", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005543", "evidence": [ { "database": "UniProtKB", "id": "F1N605", "url": "https://www.uniprot.org/uniprotkb/F1N605" } ], "pmid": "" }, { "name": "low-density lipoprotein particle receptor binding", "id": "GO:0050750", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0050750", "evidence": [ { "database": "UniProtKB", "id": "F1N605", "url": "https://www.uniprot.org/uniprotkb/F1N605" } ], "pmid": "" }, { "name": "tau protein binding", "id": "GO:0048156", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0048156", "evidence": [ { "database": "UniProtKB", "id": "F1N605", "url": "https://www.uniprot.org/uniprotkb/F1N605" } ], "pmid": "" }, { "name": "small GTPase binding", "id": "GO:0031267", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0031267", "evidence": [ { "database": "UniProtKB", "id": "F1N605", "url": "https://www.uniprot.org/uniprotkb/F1N605" } ], "pmid": "" }, { "name": "SNARE binding", "id": "GO:0000149", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000149", "evidence": [ { "database": "UniProtKB", "id": "F1N605", "url": "https://www.uniprot.org/uniprotkb/F1N605" } ], "pmid": "" }, { "name": "clathrin heavy chain binding", "id": "GO:0032050", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0032050", "evidence": [ { "database": "UniProtKB", "id": "F1N605", "url": "https://www.uniprot.org/uniprotkb/F1N605" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 23, "go_terms": [ { "name": "clathrin coat assembly", "id": "GO:0048268", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0048268", "evidence": [ { "database": "UniProtKB", "id": "F1N605", "url": "https://www.uniprot.org/uniprotkb/F1N605" } ], "pmid": "" }, { "name": "clathrin-dependent endocytosis", "id": "GO:0072583", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0072583", "evidence": [ { "database": "UniProtKB", "id": "F1N605", "url": "https://www.uniprot.org/uniprotkb/F1N605" } ], "pmid": "" }, { "name": "positive regulation of Ras protein signal transduction", "id": "GO:0046579", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0046579", "evidence": [ { "database": "UniProtKB", "id": "F1N605", "url": "https://www.uniprot.org/uniprotkb/F1N605" } ], "pmid": "" }, { "name": "membrane bending", "id": "GO:0097753", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0097753", "evidence": [ { "database": "UniProtKB", "id": "F1N605", "url": "https://www.uniprot.org/uniprotkb/F1N605" } ], "pmid": "" }, { "name": "axonogenesis", "id": "GO:0007409", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007409", "evidence": [ { "database": "UniProtKB", "id": "F1N605", "url": "https://www.uniprot.org/uniprotkb/F1N605" } ], "pmid": "" }, { "name": "learning or memory", "id": "GO:0007611", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007611", "evidence": [ { "database": "UniProtKB", "id": "F1N605", "url": "https://www.uniprot.org/uniprotkb/F1N605" } ], "pmid": "" }, { "name": "negative regulation of gene expression", "id": "GO:0010629", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0010629", "evidence": [ { "database": "UniProtKB", "id": "F1N605", "url": "https://www.uniprot.org/uniprotkb/F1N605" } ], "pmid": "" }, { "name": "receptor internalization", "id": "GO:0031623", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0031623", "evidence": [ { "database": "UniProtKB", "id": "F1N605", "url": "https://www.uniprot.org/uniprotkb/F1N605" } ], "pmid": "" }, { "name": "positive regulation of amyloid-beta formation", "id": "GO:1902004", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:1902004", "evidence": [ { "database": "UniProtKB", "id": "F1N605", "url": "https://www.uniprot.org/uniprotkb/F1N605" } ], "pmid": "" }, { "name": "intracellular iron ion homeostasis", "id": "GO:0006879", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006879", "evidence": [ { "database": "UniProtKB", "id": "F1N605", "url": "https://www.uniprot.org/uniprotkb/F1N605" } ], "pmid": "" }, { "name": "positive regulation of DNA-templated transcription", "id": "GO:0045893", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0045893", "evidence": [ { "database": "UniProtKB", "id": "F1N605", "url": "https://www.uniprot.org/uniprotkb/F1N605" } ], "pmid": "" }, { "name": "endosomal transport", "id": "GO:0016197", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016197", "evidence": [ { "database": "UniProtKB", "id": "F1N605", "url": "https://www.uniprot.org/uniprotkb/F1N605" } ], "pmid": "" }, { "name": "hemopoiesis", "id": 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"A0A3Q1LIJ0", "url": "https://www.orthodb.org/?gene=A0A3Q1LIJ0", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A3Q1M1B2", "url": "https://www.orthodb.org/?gene=A0A3Q1M1B2", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "F6PS38", "url": "https://www.orthodb.org/?gene=F6PS38", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR11544", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR11544", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00313", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00313", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "A0A3Q1LIJ0", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1LIJ0", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A3Q1LIJ0-1", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1LIJ0-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A3Q1M1B2", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1M1B2", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A3Q1M1B2-1", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1M1B2-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "F6PS38", "url": "https://www.uniprot.org/uniprotkb/F6PS38", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "F6PS38-1", "url": "https://www.uniprot.org/uniprotkb/F6PS38-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MSEAGEATSTTSTAAAAPSSSAPITTAAALPQAPAEAAPQDPAPKSPAGGGAPPAPAPAALVSGNPGGDAAPGTAAPASSAAVGSEDAEKKVLATKVLGTVKWFNVRNGYGFINRYVCVSLHTAIKKNNPRKYLRSVGDGETVEFDVVEGEKGAEAANVTGPDGVPVEGSRYAADRRRYRRGYYGRRRGPPRNYAGEEEEEGSGSSEGLEAPAAAGQFSAARSQPRRPQFRPQYRRRFPPYHVGQTFDRRSRVFPHPSRMQAGEIGEMKDGVPEGAQLQGPVHRNPTYRARYRRGPPRPRPAPAVGEAEDKENQQAANGPNQPPARRGYQRPYNYRRRPRPPNAPSQDGKETKAGEAPSENPAPAPEQSSAE", "length": 372, "header": "tr|F6PS38-1|F6PS38_BOVIN Isoform 1 of Y-box binding protein 3 OS=Bos taurus OX=9913 GN=YBX3 PE=1 SV=3 CANONICAL=F6PS38-1" }, "isoforms": [ { "isoform_ac": "A0A3Q1LIJ0-1", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1LIJ0/entry", "sequence": { "sequence": "MLMKSMPQLRSQPSPPLPLPGPARRLEELVRGHFWGSKTERGAPERARSPRARAASRRETPPPSPASGRASPRPPRPPAAPTADQPPPRCPRDSGGGGMSEAGEATSTTSTAAAAPSSSAPITTAAALPQAPAEAAPQDPAPKSPAGGGAPPAPAPAALVSGNPGGDAAPGTAAPASSAAVGSEDAEKKVLATKVLGTVKWFNVRNGYGFINRNDTKEDVFVHQTAIKKNNPRKYLRSVGDGETVEFDVVEGEKGAEAANVTGPDGVPVEGSRYAADRRRYRRGYYGRRRGPPRNYAGEEEEEGSGSSEGLEAPAAAGQFSAARSQPRRPQFRPQYRRRFPPYHVGQTFDRRSRVFPHPSRMQAGEIGEMKDGVPEGAQLQGPVHRNPTYRARYRRGPPRPRPAPAVGEAEDKENQQAANGPNQPPARRGYQRPYNYRRRPRPPNAPSQDGKETKAGEAPSENPAPAPEQSSAE", "length": 474, "header": "tr|A0A3Q1LIJ0-1|A0A3Q1LIJ0_BOVIN Computationally mapped isoform of Y-box binding protein 3 OS=Bos taurus OX=9913 GN=YBX3 PE=1 SV=1 CANONICAL=F6PS38-1" }, "locus": { "chromosome": "5", "start_pos": 98876303, "end_pos": 98853392, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000082669.2", "url": "https://www.ensembl.org/id/ENSBTAT00000082669.2" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000058871.1", "url": "https://www.ensembl.org/id/ENSBTAP00000058871.1" } ] } }, { "isoform_ac": "A0A3Q1M1B2-1", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1M1B2/entry", "sequence": { "sequence": "MLMKSMPQLRSQPSPPLPLPGPARRLEELVRGHFWGSKTERGAPERARSPRARAASRRETPPPSPASGRASPRPPRPPAAPTADQPPPRCPRDSGGGGMSEAGEATSTTSTAAAAPSSSAPITTAAALPQAPAEAAPQDPAPKSPAGGGAPPAPAPAALVSGNPGGDAAPGTAAPASSAAVGSEDAEKKVLATKVLGTVKWFNVRNGYGFINRNDTKEDVFVHQTAIKKNNPRKYLRSVGDGETVEFDVVEGEKGAEAANVTGPDGVPVEGSRYAADRRRYRRGYYGRRRGPPRNYAGEEEEEGSGSSEGLEAPAAAGQFSAARSQPRRPQFRPQYRRRFPPYHVGQTFDRRSRVFPHPSRMQAGEIGEMKDGVPEGAQLQGPVHRNPTYRARYRRGPPRPRPAPAVGEAEDKENQQAANGPNQPPARRGYQRPYNYRRRPRPPNAPSQDGKEVT", "length": 455, "header": "tr|A0A3Q1M1B2-1|F6PS38_BOVIN Computationally mapped isoform of Y-box binding protein 3 OS=Bos taurus OX=9913 GN=YBX3 PE=1 SV=1 CANONICAL=F6PS38-1" }, "locus": { "chromosome": "5", "start_pos": 98878509, "end_pos": 98853392, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000074030.3", "url": "https://www.ensembl.org/id/ENSBTAT00000074030.3" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000063490.1", "url": "https://www.ensembl.org/id/ENSBTAP00000063490.1" } ] } }, { "isoform_ac": "F6PS38-1", "url": "https://www.uniprot.org/uniprotkb/F6PS38/entry", "sequence": { "sequence": "MSEAGEATSTTSTAAAAPSSSAPITTAAALPQAPAEAAPQDPAPKSPAGGGAPPAPAPAALVSGNPGGDAAPGTAAPASSAAVGSEDAEKKVLATKVLGTVKWFNVRNGYGFINRYVCVSLHTAIKKNNPRKYLRSVGDGETVEFDVVEGEKGAEAANVTGPDGVPVEGSRYAADRRRYRRGYYGRRRGPPRNYAGEEEEEGSGSSEGLEAPAAAGQFSAARSQPRRPQFRPQYRRRFPPYHVGQTFDRRSRVFPHPSRMQAGEIGEMKDGVPEGAQLQGPVHRNPTYRARYRRGPPRPRPAPAVGEAEDKENQQAANGPNQPPARRGYQRPYNYRRRPRPPNAPSQDGKETKAGEAPSENPAPAPEQSSAE", "length": 372, "header": "tr|F6PS38-1|F6PS38_BOVIN Isoform 1 of Y-box binding protein 3 OS=Bos taurus OX=9913 GN=YBX3 PE=1 SV=3 CANONICAL=F6PS38-1" }, "locus": { "chromosome": "5", "start_pos": 98876303, "end_pos": 98853686, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000012735.7", "url": "https://www.ensembl.org/id/ENSBTAT00000012735.7" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000012735.7", "url": "https://www.ensembl.org/id/ENSBTAP00000012735.7" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [], "orthologs": [ { "uniprot_canonical_ac": "A0A8V0ZPU8-1", "protein_name": "Y-box binding protein 3", "gene_name": "YBX3", "tax_id": 9031, "organism": "Gallus gallus", "sequence": { "sequence": "MSEAAETGTASGTAPAAAAPAPPPPPPAAAPPDVKPKSPVSGAAPGASGGEVAPAASGSAAATTAAAAAGETEKKVLATKVLGTVKWFNVRNGYGFINRNDTKEDVFVHQTAIKKNNPRKYLRSVGDGETVEFDVVEGEKGAEAANVTGPDGVPVEGSRYAADRRRYRRGYFGRRRGPPRSGVEGEIKDGVTEGGQIHQQVQRNPTYRPRYRRGPLRPRPAPVAGEAENKENQHEAGAVSQQPLRRGYRRPYNYRRRPRPPNTPAQDGKETKVTETPAENPAPVTEQSGAE", "length": 291 }, "evidence": [ { "id": "F6PS38", "url": "https://omabrowser.org/oma/group/F6PS38/", "database": "OMA" } ], "glygen_name": "Chicken", "common_name": "Chicken" }, { "uniprot_canonical_ac": "F1SQ46-1", "protein_name": "Y-box binding protein 3", "gene_name": "YBX3", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MSEAGEATTTSTTSTTTTTTTLPQAPAEAAAAAPQDPAPKSPAGSGAPQAAAPAPAALVAGNPGGDAAPAAPTAPGTAAPASSAAAGSEDAEKKVLATKVLGTVKWFNVRNGYGFINRNDTKEDVFVHQTAIKKNNPRKYLRSVGDGETVEFDVVEGEKGAEAANVTGPDGVPVEGSRYAADRRRYRRGYYGRRRGPPRNAGEIGEMKDGVPEGTQLQGPVHRNPTYRPRYRSRGPPRPRPAPAVGEAEDKENQQAANGPNQPPARRGYRRPYNYRRRPRPPNAPSQDGKETKAGEAPSDNPAPATEQSSAE", "length": 312 }, "evidence": [ { "id": "F6PS38", "url": "https://omabrowser.org/oma/group/F6PS38/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "P16989-1", "protein_name": "Y-box-binding protein 3", "gene_name": "YBX3", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MSEAGEATTTTTTTLPQAPTEAAAAAPQDPAPKSPVGSGAPQAAAPAPAAHVAGNPGGDAAPAATGTAAAASLATAAGSEDAEKKVLATKVLGTVKWFNVRNGYGFINRNDTKEDVFVHQTAIKKNNPRKYLRSVGDGETVEFDVVEGEKGAEAANVTGPDGVPVEGSRYAADRRRYRRGYYGRRRGPPRNYAGEEEEEGSGSSEGFDPPATDRQFSGARNQLRRPQYRPQYRQRRFPPYHVGQTFDRRSRVLPHPNRIQAGEIGEMKDGVPEGAQLQGPVHRNPTYRPRYRSRGPPRPRPAPAVGEAEDKENQQATSGPNQPSVRRGYRRPYNYRRRPRPPNAPSQDGKEAKAGEAPTENPAPPTQQSSAE", "length": 372 }, "evidence": [ { "id": "F6PS38", "url": "https://omabrowser.org/oma/group/F6PS38/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "Q62764-1", "protein_name": "Y-box-binding protein 3", "gene_name": "Ybx3", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MSEAGEATTGGTTLPQAAADAPAAAPPDPAPKSPAASGAPQAPAPAALLAGSPGGDAAPGPAPASSAPAGSEDAEKKVLATKVLGTVKWFNVRNGYGFINRNDTKEDVFVHQTAIKKNNPRKYLRSVGDGETVEFDVVEGEKGAEAANVTGPDGVPVEGSRYAADRRRYRRGYYGRRRGPPRNYAGEEEEEGSGSSEGFEPPAADGQFSGARNQLRRPQYRPPYRQRRFPPYHVGQTFDRRSRVFPHPNRMQAGEIGEMKDGVPEGAQLQVHRNPTYRPRFRRGPARPRPAPAIGEAEDKENQQAANGPNQPSARRGFRRPYNYRRRPRPLNAVSQDGKETKAGEAPTENPAPATEQSSAE", "length": 361 }, "evidence": [ { "id": "F6PS38", "url": "https://omabrowser.org/oma/group/F6PS38/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "Q9JKB3-1", "protein_name": "Y-box-binding protein 3", "gene_name": "Ybx3", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MSEAGEATTGGTTLPQAAADAPAAAPPDPAPKSPAASGAPQAPAPAALLAGSPGGDAAPGPAPASSAPAGGEDAEKKVLATKVLGTVKWFNVRNGYGFINRNDTKEDVFVHQTAIKKNNPRKYLRSVGDGETVEFDVVEGEKGAEAANVTGPDGVPVEGSRYAADRRRYRRGYYGRRRGPPRNYAGEEEEEGSGSSEGFEPPAADGQFSGARNQLRRPQYRPPYRQRRFPPYHVGQTFDRRSRVFPHPNRMQAGEIGEMKDGVPEGTQLQAHRNPTYRPRFRRGPARPRPAPAIGEAEDKENQQAANGPNQPSARRGFRRPYNYRRRSRPLNAVSQDGKETKAGEAPTENPAPATEQSSAE", "length": 361 }, "evidence": [ { "id": "F6PS38", "url": "https://omabrowser.org/oma/group/F6PS38/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" } ], "go_annotation": { "categories": [ { "name": "Biological Process", "total": 6, "go_terms": [ { "name": "negative regulation of transcription by RNA polymerase II", "id": "GO:0000122", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000122", "evidence": [ { "database": "UniProtKB", "id": "F6PS38", "url": "https://www.uniprot.org/uniprotkb/F6PS38" } ], "pmid": "" }, { "name": "regulation of gene expression", "id": "GO:0010468", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0010468", "evidence": [ { "database": "UniProtKB", "id": "F6PS38", "url": "https://www.uniprot.org/uniprotkb/F6PS38" } ], "pmid": "" }, { "name": "negative regulation of necroptotic process", "id": "GO:0060546", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0060546", "evidence": [ { "database": "UniProtKB", "id": "F6PS38", "url": "https://www.uniprot.org/uniprotkb/F6PS38" } ], "pmid": "" }, { "name": "cellular response to tumor necrosis factor", "id": "GO:0071356", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0071356", "evidence": [ { "database": "UniProtKB", "id": "F6PS38", "url": "https://www.uniprot.org/uniprotkb/F6PS38" } ], "pmid": "" }, { "name": "cellular hyperosmotic response", "id": "GO:0071474", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0071474", "evidence": [ { "database": "UniProtKB", "id": "F6PS38", "url": "https://www.uniprot.org/uniprotkb/F6PS38" } ], "pmid": "" }, { "name": "negative regulation of intrinsic apoptotic signaling pathway in response to osmotic stress", "id": "GO:1902219", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:1902219", "evidence": [ { "database": "UniProtKB", "id": "F6PS38", "url": "https://www.uniprot.org/uniprotkb/F6PS38" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 3, "go_terms": [ { "name": "nucleus", "id": "GO:0005634", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005634", "evidence": [ { "database": "UniProtKB", "id": "F6PS38", "url": "https://www.uniprot.org/uniprotkb/F6PS38" } ], "pmid": "" }, { "name": "cytosol", "id": "GO:0005829", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005829", "evidence": [ { "database": "UniProtKB", "id": "F6PS38", "url": "https://www.uniprot.org/uniprotkb/F6PS38" } ], "pmid": "" }, { "name": "synapse", "id": "GO:0045202", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0045202", "evidence": [ { "database": "UniProtKB", "id": "F6PS38", "url": "https://www.uniprot.org/uniprotkb/F6PS38" } ], "pmid": "" } ] }, { "name": "Molecular Function", "total": 4, "go_terms": [ { "name": "ribonucleoprotein complex binding", "id": "GO:0043021", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0043021", "evidence": [ { "database": "UniProtKB", "id": "F6PS38", "url": "https://www.uniprot.org/uniprotkb/F6PS38" } ], "pmid": "" }, { "name": "nucleic acid binding", "id": "GO:0003676", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003676", "evidence": [ { "database": "UniProtKB", "id": "F6PS38", "url": "https://www.uniprot.org/uniprotkb/F6PS38" } ], "pmid": "" }, { "name": "RNA polymerase II transcription regulatory region sequence-specific DNA binding", "id": "GO:0000977", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000977", "evidence": [ { "database": "UniProtKB", "id": "F6PS38", "url": "https://www.uniprot.org/uniprotkb/F6PS38" } ], "pmid": "" }, { "name": "mRNA 3'-UTR binding", "id": "GO:0003730", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003730", "evidence": [ { "database": "UniProtKB", "id": "F6PS38", "url": "https://www.uniprot.org/uniprotkb/F6PS38" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 158, "end_pos": 160, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "F6PS38", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F6PS38" }, { "id": "PS51857", "database": "PROSITE", "url": "https://prosite.expasy.org/PS51857" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "CSD", "eco_id": "ECO_0000259", "start_pos": 96, "end_pos": 161, "start_aa": "Lys", "end_aa": "Gly", "glycosite_overlap": [] } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" }, { "name": "homologset.oma", "label": "OMA Homologs" } ], "sequence_features": 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"o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { 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"id": "F6QQY9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F6QQY9/entry#names_and_taxonomy" } ] }, { "name": "sorcin isoform 1", "type": "synonym", "evidence": [ { "id": "NP_001414800", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001414800" } ] } ], "function": [], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Bos taurus", "taxid": 9913, "evidence": [ { "database": "UniProtKB", "id": "F6QQY9", "url": "https://www.uniprot.org/uniprotkb/F6QQY9" } ], "common_name": "Bovine", "glygen_name": "Bovine", "reference_species": "Bos taurus [9913]" } ], "gene": [ { "name": "SRI", "url": "https://www.uniprot.org/uniprotkb/F6QQY9", "locus": { "chromosome": "4", "start_pos": 72315655, "end_pos": 72332628, "strand": "+", "evidence": [ { "database": "Ensembl Gene", "id": "ENSBTAG00000010390", "url": "https://www.ensembl.org/id/ENSBTAG00000010390" } ] } } ], "crossref": [ { "id": "F6QQY9", "url": "https://alphafold.ebi.ac.uk/entry/F6QQY9", "database": "AlphaFoldDB", "categories": [] }, { "id": "ENSBTAG00000010390", "url": "https://bgee.org/?page=gene&gene_id=ENSBTAG00000010390", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "cd16187", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd16187", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "508319", "url": "https://www.ncbi.nlm.nih.gov/gene/508319", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR002048", "url": "https://www.ebi.ac.uk/interpro/entry/IPR002048", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR011992", "url": "https://www.ebi.ac.uk/interpro/entry/IPR011992", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR018247", "url": "https://www.ebi.ac.uk/interpro/entry/IPR018247", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "LNQFIYC", "url": "https://omabrowser.org/oma/group/LNQFIYC/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "A0A3Q1M7S5", "url": "https://www.orthodb.org/?gene=A0A3Q1M7S5", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "F6QQY9", "url": "https://www.orthodb.org/?gene=F6QQY9", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR46735", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR46735", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR46735:SF7", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR46735:SF7", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF13499", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF13499", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF13833", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF13833", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "R-BTA-2672351", "url": "https://www.reactome.org/PathwayBrowser/#R-BTA-2672351", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "R-BTA-418359", "url": "https://www.reactome.org/PathwayBrowser/#R-BTA-418359", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "R-BTA-425561", "url": "https://www.reactome.org/PathwayBrowser/#R-BTA-425561", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "R-BTA-5578775", "url": "https://www.reactome.org/PathwayBrowser/#R-BTA-5578775", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "R-BTA-936837", "url": "https://www.reactome.org/PathwayBrowser/#R-BTA-936837", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "NP_001414800", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001414800", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A3Q1M5A2", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1M5A2", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A3Q1M5A2-1", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1M5A2-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A3Q1M7S5", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1M7S5", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A3Q1M7S5-1", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1M7S5-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0ABI0NS58", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NS58", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0ABI0NS58-1", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NS58-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "F6QQY9", "url": "https://www.uniprot.org/uniprotkb/F6QQY9", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "F6QQY9-1", "url": "https://www.uniprot.org/uniprotkb/F6QQY9-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MAYPGHPGAGGGYYAGGYGGAPGGPAFPGQTQDPLYGYFAAVAGQDGQIDADELQRCLTQSGIAGGYKPFNLETCRLMVSMLDRDMSGTMGFNEFKELWAVLNGWRQHFISFDSDRSGTVDPQELQKALTTMGFRLSPQAVNSIAKRYSTNGKITFDDYIACCVKLRALTDSFRRRDTAQQGVVNFPYDDFIQCVMSV", "length": 198, "header": "tr|F6QQY9-1|F6QQY9_BOVIN Isoform 1 of Sorcin OS=Bos taurus OX=9913 GN=SRI PE=4 SV=1 CANONICAL=F6QQY9-1" }, "isoforms": [ { "isoform_ac": "A0A3Q1M5A2-1", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1M5A2/entry", "sequence": { "sequence": "MAYPGHPGAGGGYYAGGYGGAPGGPAFPGQTQDPLYGYFAAVAGQDGQIDADELQRCLTQSGIAGGYKPFNLETCRLMVSMLDRDMSGTMGFNEFKELWAVLNGWRQHFISFDSDRSGTVDPQELQKALTTMGFRLSPQAVNSIAKRYSTNGKITFDDYIACCVKLRALTDSFRRRDTAQQGVVNFPYDDTRS", "length": 193, "header": "tr|A0A3Q1M5A2-1|F6QQY9_BOVIN Computationally mapped isoform of Sorcin OS=Bos taurus OX=9913 GN=SRI PE=4 SV=1 CANONICAL=F6QQY9-1" }, "locus": { "chromosome": "4", "start_pos": 72332391, "end_pos": 72315796, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000087236.2", "url": "https://www.ensembl.org/id/ENSBTAT00000087236.2" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000063458.2", "url": "https://www.ensembl.org/id/ENSBTAP00000063458.2" } ] } }, { "isoform_ac": "A0A3Q1M7S5-1", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1M7S5/entry", "sequence": { "sequence": "MAYPGHPGAGGGYYAGGYGGAPGGPAFPGQTQDPLYGYFAAVAGQDGQIDADELQRCLTQSGIAGGYKPFNLETCRLMVSMLDRDMSGTMGFNEFKELWAVLNGWRQHFISFDSDRSGTVDPQELQKALTTMGFRLSPQAVNSIAKRYSTNGKITFDDYIACCVKLRALTDSFRRRDTAQQGVVNFPYDDVSLSKFITE", "length": 199, "header": "tr|A0A3Q1M7S5-1|A0A3Q1M7S5_BOVIN Computationally mapped isoform of Sorcin OS=Bos taurus OX=9913 GN=SRI PE=4 SV=2 CANONICAL=F6QQY9-1" }, "locus": { "chromosome": "4", "start_pos": 72332391, "end_pos": 72321286, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000073309.2", "url": "https://www.ensembl.org/id/ENSBTAT00000073309.2" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000066124.2", "url": "https://www.ensembl.org/id/ENSBTAP00000066124.2" } ] } }, { "isoform_ac": "A0ABI0NS58-1", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NS58/entry", "sequence": { "sequence": "MQDGQIDADELQRCLTQSGIAGGYKPFNLETCRLMVSMLDRDMSGTMGFNEFKELWAVLNGWRQHFISFDSDRSGTVDPQELQKALTTMGFRLSPQAVNSIAKRYSTNGKITFDDYIACCVKLRALTDSFRRRDTAQQGVVNFPYDDFIQCVMSV", "length": 155, "header": "tr|A0ABI0NS58-1|A0ABI0NS58_BOVIN Computationally mapped isoform of Sorcin OS=Bos taurus OX=9913 GN=SRI PE=4 SV=1 CANONICAL=F6QQY9-1" }, "locus": { "chromosome": "4", "start_pos": 72341668, "end_pos": 72319630, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000139555.1", "url": "https://www.ensembl.org/id/ENSBTAT00000139555.1" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000105699.1", "url": "https://www.ensembl.org/id/ENSBTAP00000105699.1" } ] } }, { "isoform_ac": "F6QQY9-1", "url": "https://www.uniprot.org/uniprotkb/F6QQY9/entry", "sequence": { "sequence": "MAYPGHPGAGGGYYAGGYGGAPGGPAFPGQTQDPLYGYFAAVAGQDGQIDADELQRCLTQSGIAGGYKPFNLETCRLMVSMLDRDMSGTMGFNEFKELWAVLNGWRQHFISFDSDRSGTVDPQELQKALTTMGFRLSPQAVNSIAKRYSTNGKITFDDYIACCVKLRALTDSFRRRDTAQQGVVNFPYDDFIQCVMSV", "length": 198, "header": "tr|F6QQY9-1|F6QQY9_BOVIN Isoform 1 of Sorcin OS=Bos taurus OX=9913 GN=SRI PE=4 SV=1 CANONICAL=F6QQY9-1" }, "locus": { "chromosome": "4", "start_pos": 72332391, "end_pos": 72319630, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000053811.4", "url": "https://www.ensembl.org/id/ENSBTAT00000053811.4" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000052219.3", "url": "https://www.ensembl.org/id/ENSBTAP00000052219.3" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [ { "id": "R-BTA-2672351", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-BTA-2672351", "resource": "Reactome", "description": "Stimuli-sensing channels" }, { "id": "R-BTA-418359", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-BTA-418359", "resource": "Reactome", "description": "Reduction of cytosolic Ca++ levels" }, { "id": "R-BTA-425561", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-BTA-425561", "resource": "Reactome", "description": "Sodium/Calcium exchangers" }, { "id": "R-BTA-5578775", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-BTA-5578775", "resource": "Reactome", "description": "Ion homeostasis" }, { "id": "R-BTA-936837", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-BTA-936837", "resource": "Reactome", "description": "Ion transport by P-type ATPases" } ], "orthologs": [ { "uniprot_canonical_ac": "A0A8I5Y6E8-1", "protein_name": "ADAM metallopeptidase domain 22", "gene_name": "Adam22", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MQAVAAAFFWLLCVLGTYPLARCGRAGDASLRELERGDGNRFLERQSTVPLRLIYRLGGEDETQHEQLNTRVRGDPGGRQPTHVDKASFRVDAFGTSFILDVLLNHELLSSGYVERHIEHGGKVVENKGGEHCYYQGQIRGNPASFVALSTCHGLHGMFYDGNHTYLIEPEENEMSQESQFHSVYKSRLLEFPLDDLPSEFQRINITAPQFTLKPRLKRRKRQLLRFPRNVEEETKYIELMIVNDHLMFKKHRLSVVYTNTYAKSVVNMADVIYKDQLKTRIVLVAMETWAADNKFAISENPLVTLREFMKYRRDFIKEKADAVHLFSGSQFESSRSGAAYIGGICSLLRGGGVNEFGKTDLMAVTLAQSLAHNIGIISDKRKLASGECKCEDTWSGCIMGDTGYYLPKKFTQCNIEEYHDFLNSGGGACLFNKPSKLLDPPECGNGFIETGEECDCGTPAECALEGAECCKKCTLTQDSQCSDGLCCKKCKFQPLGTVCREAVNDCDIREICSGNSSQCAPNVHKMDGYSCDGTQGICFGGRCKTRDRQCKYIWGQKVTASDRYCYEKLNIEGTEKGNCGKDKDTWTQCNKRDVLCGFLLCTNIGNIPRLGELDGEITSTLVVQQGRTLNCSGGHVKLEEDVDLGYVEDGTPCGPQMMCLEHRCLPMASFNFSTCLSNKAGTVCSGNGVCSNELKCVCNRHWTGADCGTHFPHNDDAKTGITLSGNGVAGTNIIIGIIAGTILVLALILGITAWGYKNYREQRQLPQGDYVKKPGDGDSFYSDFPPGGSADSASSSKKRSAFLSHFQISTCSITHYSISQNISLFCSRSNGLSHSWSERIPDTKHISDICENGRPRSNSWQGNVGGNKKKIRGKRFRPRSNSTEREPQAPEPGHSLAQTSPGISPGGSDSPQTGSLDHRTLSPAKSPSSSTGSIASSRKYPYPMPPLPDEEKTVNRQSARLWETSI", "length": 967 }, "evidence": [ { "id": "F6QQY9", "url": "https://omabrowser.org/oma/group/F6QQY9/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "F1R4I7-1", "protein_name": "Sorcin isoform X1", "gene_name": "sri", "tax_id": 7955, "organism": "Danio rerio", "sequence": { "sequence": "MNYQGYGAPPAAGGYPGGFPGQQQDPLYGYFTAIAGQDGQISAEELQACLTQANFSGGYRPFNLETCRLMISMLDRDMSYSMGFNEFKELWAVLNGWKQHFMSIDRDMSGTVDPQEMNQAISSMGYRLSPQAMNSIIKRYSSQGKITFDDYVACCVKLRSLTDVFRKRDQAQQGMATFQYDDFIHCTMSI", "length": 190 }, "evidence": [ { "id": "F6QQY9", "url": "https://omabrowser.org/oma/group/F6QQY9/", "database": "OMA" } ], "glygen_name": "Zebrafish", "common_name": "Zebrafish" }, { "uniprot_canonical_ac": "F1S340-1", "protein_name": "Sorcin", "gene_name": "SRI", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MAYPGHPGAGGGGYYPGGYGGAPGGPAFPAQTQDPLYGYFAAVAGQDGQIDADELQRCLTQSGIAGGYKPFNLETCRLMVSMLDRDMSGTMGFNEFKELWAVLNGWRQHFISFDSDRSGTVDPQELQKALTTMGFRLSPQAVNSIAKRYSTNGKITFDDYIACCVKLRALTDSFRRRDTAQQGVVNFPYDDFIQCVMSV", "length": 199 }, "evidence": [ { "id": "F6QQY9", "url": "https://omabrowser.org/oma/group/F6QQY9/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "P30626-1", "protein_name": "Sorcin", "gene_name": "SRI", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MAYPGHPGAGGGYYPGGYGGAPGGPAFPGQTQDPLYGYFAAVAGQDGQIDADELQRCLTQSGIAGGYKPFNLETCRLMVSMLDRDMSGTMGFNEFKELWAVLNGWRQHFISFDTDRSGTVDPQELQKALTTMGFRLSPQAVNSIAKRYSTNGKITFDDYIACCVKLRALTDSFRRRDTAQQGVVNFPYDDFIQCVMSV", "length": 198 }, "evidence": [ { "id": "F6QQY9", "url": "https://omabrowser.org/oma/group/F6QQY9/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "Q6P069-1", "protein_name": "Sorcin", "gene_name": "Sri", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MAYPGHPGAGGGYYPGGYGGAPGGPAFPGQTQDPLYGYFAAVAGQDGQIDADELQRCLTQSGIAGGYKPFNLETCRLMVSMLDRDMSGTMGFNEFKELWAVLNGWRQHFISFDSDRSGTVDPQELQKALTTMGFRLSPQTVNSVAKRYSTSGKITFDDYIACCVKLRALTDSFRRRDSGQQGVVNFSYDDFIQCVMTV", "length": 198 }, "evidence": [ { "id": "F6QQY9", "url": "https://omabrowser.org/oma/group/F6QQY9/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" } ], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 5, "go_terms": [ { "name": "cytoplasm", "id": "GO:0005737", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005737", "evidence": [ { "database": "UniProtKB", "id": "F6QQY9", "url": "https://www.uniprot.org/uniprotkb/F6QQY9" } ], "pmid": "" }, { "name": "endomembrane system", "id": "GO:0012505", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0012505", "evidence": [ { "database": "UniProtKB", "id": "F6QQY9", "url": "https://www.uniprot.org/uniprotkb/F6QQY9" } ], "pmid": "" }, { "name": "plasma membrane", "id": "GO:0005886", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005886", "evidence": [ { "database": "UniProtKB", "id": "F6QQY9", "url": "https://www.uniprot.org/uniprotkb/F6QQY9" } ], "pmid": "" }, { "name": "vesicle", "id": "GO:0031982", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0031982", "evidence": [ { "database": "UniProtKB", "id": "F6QQY9", "url": "https://www.uniprot.org/uniprotkb/F6QQY9" } ], "pmid": "" }, { "name": "Z disc", "id": "GO:0030018", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030018", "evidence": [ { "database": "UniProtKB", "id": "F6QQY9", "url": "https://www.uniprot.org/uniprotkb/F6QQY9" } ], "pmid": "" } ] }, { "name": "Molecular Function", "total": 4, "go_terms": [ { "name": "calcium ion binding", "id": "GO:0005509", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005509", "evidence": [ { "database": "UniProtKB", "id": "F6QQY9", "url": "https://www.uniprot.org/uniprotkb/F6QQY9" } ], "pmid": "" }, { "name": "transcription regulator inhibitor activity", "id": "GO:0140416", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0140416", "evidence": [ { "database": "UniProtKB", "id": "F6QQY9", "url": "https://www.uniprot.org/uniprotkb/F6QQY9" } ], "pmid": "" }, { "name": "DNA-binding transcription factor binding", "id": "GO:0140297", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0140297", "evidence": [ { "database": "UniProtKB", "id": "F6QQY9", "url": "https://www.uniprot.org/uniprotkb/F6QQY9" } ], "pmid": "" }, { "name": "protein sequestering activity", "id": "GO:0140311", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0140311", "evidence": [ { "database": "UniProtKB", "id": "F6QQY9", "url": "https://www.uniprot.org/uniprotkb/F6QQY9" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 3, "go_terms": [ { "name": "negative regulation of cardiac muscle contraction", "id": "GO:0055118", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0055118", "evidence": [ { "database": "UniProtKB", "id": "F6QQY9", "url": "https://www.uniprot.org/uniprotkb/F6QQY9" } ], "pmid": "" }, { "name": "positive regulation of release of sequestered calcium ion into cytosol", "id": "GO:0051281", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0051281", "evidence": [ { "database": "UniProtKB", "id": "F6QQY9", "url": "https://www.uniprot.org/uniprotkb/F6QQY9" } ], "pmid": "" }, { "name": "regulation of insulin secretion involved in cellular response to glucose stimulus", "id": "GO:0061178", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0061178", "evidence": [ { "database": "UniProtKB", "id": "F6QQY9", "url": "https://www.uniprot.org/uniprotkb/F6QQY9" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "F6QQY9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F6QQY9" }, { "id": "PS50222", "database": "PROSITE", "url": "https://prosite.expasy.org/PS50222" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "EF-hand", "eco_id": "ECO_0000259", "start_pos": 100, "end_pos": 135, "start_aa": "Ala", "end_aa": "Arg", "glycosite_overlap": [] } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" }, { "name": "homologset.oma", "label": "OMA Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ], "tool_support": { "graph_view": "yes" } }, { "uniprot_canonical_ac": "F6QIF2-1", "uniprot_ac": "F6QIF2", "uniprot_id": "F6QIF2_BOVIN", "mass": { "chemical_mass": 111211.0, "monoisotopic_mass": 111211.0 }, "refseq": { "ac": "XP_010799470", "name": "run domain Beclin-1-interacting and cysteine-rich domain-containing protein isoform X2", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_010799470" }, "gene_names": [ { "name": "RUBCN", "type": "recommended", "evidence": [ { "id": "F6QIF2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F6QIF2" } ] }, { "name": "KIAA0226", "type": "synonym", "evidence": [ { "id": "XP_010799470", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_010799470" } ] }, { "name": "RUBCN", "type": "synonym", "evidence": [ { "id": "XP_010799470", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_010799470" } ] } ], "protein_names": [ { "name": "Rubicon autophagy regulator", "type": "synonym", "evidence": [ { "id": "F6QIF2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F6QIF2/entry#names_and_taxonomy" } ] }, { "name": "run domain Beclin-1-interacting and cysteine-rich domain-containing protein isoform X2", "type": "synonym", "evidence": [ { "id": "XP_010799470", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_010799470" } ] } ], "function": [], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Bos taurus", "taxid": 9913, "evidence": [ { "database": "UniProtKB", "id": "F6QIF2", "url": "https://www.uniprot.org/uniprotkb/F6QIF2" } ], "common_name": "Bovine", "glygen_name": "Bovine", "reference_species": "Bos taurus [9913]" } ], "gene": [ { "name": "RUBCN", "url": "https://www.uniprot.org/uniprotkb/F6QIF2", "locus": { "chromosome": "1", "start_pos": 70433477, "end_pos": 70384588, "strand": "-", "evidence": [ { "database": "Ensembl Gene", "id": "ENSBTAG00000001890", "url": "https://www.ensembl.org/id/ENSBTAG00000001890" } ] } } ], "crossref": [ { "id": "F6QIF2", "url": "https://alphafold.ebi.ac.uk/entry/F6QIF2", "database": "AlphaFoldDB", "categories": [] }, { "id": "ENSBTAG00000001890", "url": "https://bgee.org/?page=gene&gene_id=ENSBTAG00000001890", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "cd17686", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd17686", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "508354", "url": "https://www.ncbi.nlm.nih.gov/gene/508354", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR004012", "url": "https://www.ebi.ac.uk/interpro/entry/IPR004012", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR025258", "url": "https://www.ebi.ac.uk/interpro/entry/IPR025258", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR037213", "url": "https://www.ebi.ac.uk/interpro/entry/IPR037213", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR048569", "url": "https://www.ebi.ac.uk/interpro/entry/IPR048569", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR052428", "url": "https://www.ebi.ac.uk/interpro/entry/IPR052428", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "A0A3Q1M1C0", "url": "https://www.orthodb.org/?gene=A0A3Q1M1C0", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "E1BK05", "url": "https://www.orthodb.org/?gene=E1BK05", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "F6QIF2", "url": "https://www.orthodb.org/?gene=F6QIF2", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR45971", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR45971", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR45971:SF3", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR45971:SF3", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF02759", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF02759", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF13901", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF13901", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF21054", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF21054", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "XP_010799470", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_010799470", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A3Q1M1C0", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1M1C0", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A3Q1M1C0-1", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1M1C0-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "E1BK05", "url": "https://www.uniprot.org/uniprotkb/E1BK05", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "E1BK05-1", "url": "https://www.uniprot.org/uniprotkb/E1BK05-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "F6QIF2", "url": "https://www.uniprot.org/uniprotkb/F6QIF2", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "F6QIF2-1", "url": "https://www.uniprot.org/uniprotkb/F6QIF2-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MRPEGAGMELGGCEKGLPEESRREHWQLLGNLKTTVEGLVSANSPNVWSKYGGLERLCRDMQSILHHGLIHDQVCCRQTDYWQFVKDIRWLSPHSAFHVEKFISLHENGQSSTDGVSERAVAELWLQHSLQCHCLSAQLRPLLGDRQYIRKFYTDTAFLLSDAHVTAMLQCLEAVEQNNPRLLAQIDASMFARKHESPLLVTKSQSLTALPGSAYTPSTNSGQHSYFGSFSSLHQIPHHSLERRSTSFSLSGPPRKPQESRGPVSAAEDQTVLDPLLPITALAKDSPSTPNEMSSSTLTSPLEASWVSSQNDSPSDASEGPEYLAIGNQDPRGRTASCQSHSSNTESSSSNLFSSSSSQKPDSAASSLGDQEGGRQSQLSSVLRRSSFSEGQTLTVTGGTKKSHTRSHSDTNIASRGAPESCSDKSKLRGPLSYSGQSSEVSTPSSLYVEYEGSQYLCSGEGMFRRPSEGQSLISYLSEQDFGSCADLEKENAHFSISESLIAAIELMKCNMMSQCLEEEEGEEDSDREIQELKQKIRLRRQQIRTKNLLPGYQEMEHGSFRLTSSSSQFSSRDSAQFSDSGSADDEVDEFEIQDGSEGSNLTHMSKNGLSVSVASLFSDADIRRSTPSNSKSFISSQSFSHCFLHSTSAEAVAMGLLKQFEGMQLPAASELEWLVPEHDAPQKLLPIPDSLPISPDDGQHADIYKLRIRVRGNLEWAPPRPQIIFNVHPAPTRKIAVAKQNYRCAGCGIRTDPDYIKRLRYCEYLGKYFCQCCHENAQMVIPSRILRKWDFSKYYVSNFSKDLLIKIWNDPLFNVQDINSALYRKVKLLNHVRLLRIQLYHMKNMFKTCRLAKELLDAFDTVPGHLTEDLHLYSLNDLTATRKGELGPRLAELTRAGAAHVERCVLCQAKGFICEFCQNEDDIIFPFELHKCRICEECKACYHKTCFKSGSCPRCERLQARRELLAKQSLESYMSDYEEEPTEALALEATDLETT", "length": 996, "header": "tr|F6QIF2-1|F6QIF2_BOVIN Isoform 1 of Rubicon autophagy regulator OS=Bos taurus OX=9913 GN=RUBCN PE=4 SV=4 CANONICAL=F6QIF2-1" }, "isoforms": [ { "isoform_ac": "A0A3Q1M1C0-1", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1M1C0/entry", "sequence": { "sequence": "MRPEGAGMELGGCEKGLPEESRREHWQLLGNLKTTVEGLVSANSPNVWSKYGGLERLCRDMQSILHHGLIHDQVCCRQTDYWQFVKDIRWLSPHSAFHVEKFISLHENGQSSTDGVSERAVAELWLQHSLQCHCLSAQLRPLLGDRQYIRKFYTDTAFLLSDAHVTAMLQCLEAVEQNNPRLLAQIDASMFARKHESPLLVTKSQSLTALPGSAYTPSTNSGQHSYFGSFSSLHQIPHHSLERRSTSFSLSGPPRKPQESRGPVSAAEDQTVLDPLLPITALAKDSPSTPNEMSSSTLTSPLEASWVSSQNDSPSDASEGPEYLAIGNQDPRGRTASCQSHSSNTESSSSNLFSSSSSQKPDSAASSLGDQEGGRQSQLSSVLRRSSFSEGQTLTVTGGTKKSHTRSHSDTNIASRGAPGGPRNITIIVEDPIAESCSDKSKLRGPLSYSGQSSEVSTPSSLYVEYEGSQYLCSGEGMFRRPSEGQSLISYLSEQDFGSCADLEKENAHFSISESLIAAIELMKCNMMSQCLEEEEGEEDSDREIQELKQKIRLRRQQIRTKNLLPGYQEMEHGSFRLTSSSSQFSSRDSAQFSDSGSADDEVDEFEIQDADIRRSTPSNSKSFISSQSFSHCFLHSTSAEAVAMGLLKQFEGMQLPAASELEWLVPEHDAPQKLLPIPDSLPISPDDGQHADIYKLRIRVRGNLEWAPPRPQIIFNVHPAPTRKIAVAKQNYRCAGCGIRTDPDYIKRLRYCEYLGKYFCQCCHENAQMVIPSRILRKWDFSKYYVSNFSKDLLIKIWNDPLFNVQDINSALYRKVKLLNHVRLLRIQLYHMKNMFKTCRLAKELLDAFDTVPGHLTEDLHLYSLNDLTATRKGELGPRLAELTRAGAAHVERCVLCQAKGFICEFCQNEDDIIFPFELHKCRICEECKACYHKTCFKSGSCPRCERLQARRELLAKQSLESYMSDYEEEPTEALALEATDLETT", "length": 986, "header": "tr|A0A3Q1M1C0-1|F6QIF2_BOVIN Computationally mapped isoform of Rubicon autophagy regulator OS=Bos taurus OX=9913 GN=RUBCN PE=4 SV=3 CANONICAL=F6QIF2-1" }, "locus": { "chromosome": "1", "start_pos": 70433015, "end_pos": 70384764, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000082224.3", "url": "https://www.ensembl.org/id/ENSBTAT00000082224.3" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000067098.3", "url": "https://www.ensembl.org/id/ENSBTAP00000067098.3" } ] } }, { "isoform_ac": "E1BK05-1", "url": "https://www.uniprot.org/uniprotkb/E1BK05/entry", "sequence": { "sequence": "MRPEGAGMELGGCEKGLPEESRREHWQLLGNLKTTVEGLVSANSPNVWSKYGGLERLCRDMQSILHHGLIHDQVCCRQTDYWQFVKDIRWLSPHSAFHVEKFISLHENGQSSTDGVSERAVAELWLQHSLQCHCLSAQLRPLLGDRQYIRKFYTDTAFLLSDAHVTAMLQCLEAVEQNNPRLLAQIDASMFARKHESPLLVTKSQSLTALPGSAYTPSTNSGQHSYFGSFSSLHQIPHHSLERRSTSFSLSGPPRKPQESRGPVSAAEDQTVLDPLLPITALAKDSPSTPNEMSSSTLTSPLEASWVSSQNDSPSDASEGPEYLAIGNQDPRGRTASCQSHSSNTESSSSNLFSSSSSQKPDSAASSLGDQEGGRQSQLSSVLRRSSFSEGQTLTVTGGTKKSHTRSHSDTNIASRGAPEGSQYLCSGEGMFRRPSEGQSLISYLSEQDFGSCADLEKENAHFSISESLIAAIELMKCNMMSQCLEEEEGEEDSDREIQELKQKIRLRRQQIRTKNLLPGYQEMEHGSFRLTSSSSQFSSRDSAQFSDSGSADDEVDEFEIQDADIRRSTPSNSKSFISSQSFSHCFLHSTSAEAVAMGLLKQFEGMQLPAASELEWLVPEHDAPQKLLPIPDSLPISPDDGQHADIYKLRIRVRGNLEWAPPRPQIIFNVHPAPTRKIAVAKQNYRCAGCGIRTDPDYIKRLRYCEYLGKYFCQCCHENAQMVIPSRILRKWDFSKYYVSNFSKDLLIKIWNDPLFNVQDINSALYRKVKLLNHVRLLRIQLYHMKNMFKTCRLAKELLDAFDTVPGHLTEDLHLYSLNDLTATRKGELGPRLAELTRAGAAHVERCVLCQAKGFICEFCQNEDDIIFPFELHKCRICEECKACYHKTCFKSGSCPRCERLQARRELLAKQSLESYMSDYEEEPTEALALEATDLETT", "length": 939, "header": "tr|E1BK05-1|E1BK05_BOVIN Computationally mapped isoform of Rubicon autophagy regulator OS=Bos taurus OX=9913 GN=RUBCN PE=4 SV=2 CANONICAL=F6QIF2-1" }, "locus": { "chromosome": "1", "start_pos": 70433015, "end_pos": 70384764, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000061001.5", "url": "https://www.ensembl.org/id/ENSBTAT00000061001.5" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000053836.3", "url": "https://www.ensembl.org/id/ENSBTAP00000053836.3" } ] } }, { "isoform_ac": "F6QIF2-1", "url": "https://www.uniprot.org/uniprotkb/F6QIF2/entry", "sequence": { "sequence": "MRPEGAGMELGGCEKGLPEESRREHWQLLGNLKTTVEGLVSANSPNVWSKYGGLERLCRDMQSILHHGLIHDQVCCRQTDYWQFVKDIRWLSPHSAFHVEKFISLHENGQSSTDGVSERAVAELWLQHSLQCHCLSAQLRPLLGDRQYIRKFYTDTAFLLSDAHVTAMLQCLEAVEQNNPRLLAQIDASMFARKHESPLLVTKSQSLTALPGSAYTPSTNSGQHSYFGSFSSLHQIPHHSLERRSTSFSLSGPPRKPQESRGPVSAAEDQTVLDPLLPITALAKDSPSTPNEMSSSTLTSPLEASWVSSQNDSPSDASEGPEYLAIGNQDPRGRTASCQSHSSNTESSSSNLFSSSSSQKPDSAASSLGDQEGGRQSQLSSVLRRSSFSEGQTLTVTGGTKKSHTRSHSDTNIASRGAPESCSDKSKLRGPLSYSGQSSEVSTPSSLYVEYEGSQYLCSGEGMFRRPSEGQSLISYLSEQDFGSCADLEKENAHFSISESLIAAIELMKCNMMSQCLEEEEGEEDSDREIQELKQKIRLRRQQIRTKNLLPGYQEMEHGSFRLTSSSSQFSSRDSAQFSDSGSADDEVDEFEIQDGSEGSNLTHMSKNGLSVSVASLFSDADIRRSTPSNSKSFISSQSFSHCFLHSTSAEAVAMGLLKQFEGMQLPAASELEWLVPEHDAPQKLLPIPDSLPISPDDGQHADIYKLRIRVRGNLEWAPPRPQIIFNVHPAPTRKIAVAKQNYRCAGCGIRTDPDYIKRLRYCEYLGKYFCQCCHENAQMVIPSRILRKWDFSKYYVSNFSKDLLIKIWNDPLFNVQDINSALYRKVKLLNHVRLLRIQLYHMKNMFKTCRLAKELLDAFDTVPGHLTEDLHLYSLNDLTATRKGELGPRLAELTRAGAAHVERCVLCQAKGFICEFCQNEDDIIFPFELHKCRICEECKACYHKTCFKSGSCPRCERLQARRELLAKQSLESYMSDYEEEPTEALALEATDLETT", "length": 996, "header": "tr|F6QIF2-1|F6QIF2_BOVIN Isoform 1 of Rubicon autophagy regulator OS=Bos taurus OX=9913 GN=RUBCN PE=4 SV=4 CANONICAL=F6QIF2-1" }, "locus": { "chromosome": "1", "start_pos": 70433015, "end_pos": 70384764, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000002461.8", "url": "https://www.ensembl.org/id/ENSBTAT00000002461.8" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000002461.8", "url": "https://www.ensembl.org/id/ENSBTAP00000002461.8" } ] } } ], "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "other", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 983, "start_aa": "Thr", "end_pos": 983, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr983", "evidence": [ { "id": "", "database": "GlyGen", "url": "https://data.glygen.org/" } ], "filter_code": "000000000000000010000.00000000001000.0.01000" } ], "phosphorylation": [], "glycation": [], "keywords": [ "glycoprotein", "glycoprotein_predicted" ], "publication": [], "pathway": [], "orthologs": [], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 2, "go_terms": [ { "name": "late endosome", "id": "GO:0005770", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005770", "evidence": [ { "database": "UniProtKB", "id": "F6QIF2", "url": "https://www.uniprot.org/uniprotkb/F6QIF2" } ], "pmid": "" }, { "name": "early endosome", "id": "GO:0005769", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005769", "evidence": [ { "database": "UniProtKB", "id": "F6QIF2", "url": "https://www.uniprot.org/uniprotkb/F6QIF2" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 3, "go_terms": [ { "name": "autophagy", "id": "GO:0006914", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006914", "evidence": [ { "database": "UniProtKB", "id": "F6QIF2", "url": "https://www.uniprot.org/uniprotkb/F6QIF2" } ], "pmid": "" }, { "name": "negative regulation of autophagosome maturation", "id": "GO:1901097", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:1901097", "evidence": [ { "database": "UniProtKB", "id": "F6QIF2", "url": "https://www.uniprot.org/uniprotkb/F6QIF2" } ], "pmid": "" }, { "name": "negative regulation of endocytosis", "id": "GO:0045806", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0045806", "evidence": [ { "database": "UniProtKB", "id": "F6QIF2", "url": "https://www.uniprot.org/uniprotkb/F6QIF2" } ], "pmid": "" } ] }, { "name": "Molecular Function", "total": 1, "go_terms": [ { "name": "phosphatidylinositol phosphate binding", "id": "GO:1901981", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:1901981", "evidence": [ { "database": "UniProtKB", "id": "F6QIF2", "url": "https://www.uniprot.org/uniprotkb/F6QIF2" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 311, "end_pos": 313, "annotation": "n_glycosylation_sequon" }, { "start_pos": 601, "end_pos": 603, "annotation": "n_glycosylation_sequon" }, { "start_pos": 799, "end_pos": 801, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "F6QIF2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F6QIF2" }, { "id": "PS50826", "database": "PROSITE", "url": "https://prosite.expasy.org/PS50826" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "RUN", "eco_id": "ECO_0000259", "start_pos": 48, "end_pos": 189, "start_aa": "Trp", "end_aa": "Ser", "glycosite_overlap": [] } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" } ], "sequence_features": { "n_linked_sites": [], 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"monoisotopic_mass": 87327.0 }, "refseq": { "ac": "XP_010808732", "name": "transcription termination factor 1 isoform X1", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_010808732" }, "gene_names": [ { "name": "TTF1", "type": "recommended", "evidence": [ { "id": "F6QJN7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F6QJN7" } ] }, { "name": "TTF1", "type": "synonym", "evidence": [ { "id": "XP_010808732", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_010808732" } ] } ], "protein_names": [ { "name": "Transcription termination factor 1", "type": "synonym", "evidence": [ { "id": "F6QJN7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F6QJN7/entry#names_and_taxonomy" } ] }, { "name": "transcription termination factor 1 isoform X1", "type": "synonym", "evidence": [ { "id": "XP_010808732", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_010808732" } ] } ], "function": [], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Bos taurus", "taxid": 9913, "evidence": [ { "database": "UniProtKB", "id": "F6QJN7", "url": "https://www.uniprot.org/uniprotkb/F6QJN7" } ], "common_name": "Bovine", "glygen_name": "Bovine", "reference_species": "Bos taurus [9913]" } ], "gene": [ { "name": "TTF1", "url": "https://www.uniprot.org/uniprotkb/F6QJN7", "locus": { "chromosome": "11", "start_pos": 102445603, "end_pos": 102480273, "strand": "+", "evidence": [ { "database": "Ensembl Gene", "id": "ENSBTAG00000018710", "url": "https://www.ensembl.org/id/ENSBTAG00000018710" } ] } } ], "crossref": [ { "id": "F6QJN7", "url": "https://alphafold.ebi.ac.uk/entry/F6QJN7", "database": "AlphaFoldDB", "categories": [] }, { "id": "ENSBTAG00000018710", "url": "https://bgee.org/?page=gene&gene_id=ENSBTAG00000018710", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "524585", "url": "https://www.ncbi.nlm.nih.gov/gene/524585", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR001005", "url": "https://www.ebi.ac.uk/interpro/entry/IPR001005", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR009057", "url": "https://www.ebi.ac.uk/interpro/entry/IPR009057", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR053078", "url": "https://www.ebi.ac.uk/interpro/entry/IPR053078", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "PKHFRKD", "url": "https://omabrowser.org/oma/group/PKHFRKD/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "F6QJN7", "url": "https://www.orthodb.org/?gene=F6QJN7", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR46760", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR46760", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR46760:SF1", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR46760:SF1", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF13921", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF13921", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "XP_010808732", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_010808732", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "F6QJN7", "url": "https://www.uniprot.org/uniprotkb/F6QJN7", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "F6QJN7-1", "url": "https://www.uniprot.org/uniprotkb/F6QJN7-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MERESSSLETQTPIFVKKKAKHSKHKDRHRRHSQESFRAAPLANEQCDITKSKKKRKASQRLVSSPLKITEICDETEMATSKPKKKKKRRKSASGVDEETGVAYILVDKENIENTPFRSDVDVVYVDASKEQKSTERPEVDEPHSGTKPLENTSEELHSEVRKKKKKKKHKKRQREVESWDAVQESPGASIALPRAASQEQEPQPQVDQEEGIVQLSMSAGHSKSRKRKRKHPDPPEFEALAAPERAQSVYSEGSRVADEVETSGGSQDSSGLKKKSKKRKRRSLESTVEPGDFSVPRRSSEDTPLDSLEGTLVEGSAKPRPQEENPQACSKKVQRSEPTNDDESNSAKDSVAKYLSEDSRDSEDPEVDLESAVKQLQEFIPDIKDRAATTIKRMYRDDLGRFKEFKAQGVTIKFGKFSVKENQQLEKNVQEFLSLTGIENADKLLYTDRYPEEKSVITDLKRKYAFRVHIGKGIARPWKLVYYRAKKMFDVNNYKGRYSKGDTEKLKIYQSLHGNDWKKIGEMVSRSSLSVALKFSQINGQINHGAWSKTETQKLIKAVEEVILKKMSPQELNEMDSKLQLNPEGRLSIVREKLYKGISWVEVEARVETRNWMQCKSKWTEILTKRMTNGRDVYRGVNALQAKINLIERLYEINVQDVNEIDWEDLASIIGDVPPSYVQTKFYKLKATCVPFWQKKTFPEIIDYLYETSLPLLKEKLEKKMEKKGTEIQAPAAPKPVFLFRDIFYYDDDDSEGEDRDEKS", "length": 761, "header": "tr|F6QJN7-1|F6QJN7_BOVIN Isoform 1 of Transcription termination factor 1 OS=Bos taurus OX=9913 GN=TTF1 PE=4 SV=2 CANONICAL=F6QJN7-1" }, "isoforms": [ { "isoform_ac": "F6QJN7-1", "url": "https://www.uniprot.org/uniprotkb/F6QJN7/entry", "sequence": { "sequence": "MERESSSLETQTPIFVKKKAKHSKHKDRHRRHSQESFRAAPLANEQCDITKSKKKRKASQRLVSSPLKITEICDETEMATSKPKKKKKRRKSASGVDEETGVAYILVDKENIENTPFRSDVDVVYVDASKEQKSTERPEVDEPHSGTKPLENTSEELHSEVRKKKKKKKHKKRQREVESWDAVQESPGASIALPRAASQEQEPQPQVDQEEGIVQLSMSAGHSKSRKRKRKHPDPPEFEALAAPERAQSVYSEGSRVADEVETSGGSQDSSGLKKKSKKRKRRSLESTVEPGDFSVPRRSSEDTPLDSLEGTLVEGSAKPRPQEENPQACSKKVQRSEPTNDDESNSAKDSVAKYLSEDSRDSEDPEVDLESAVKQLQEFIPDIKDRAATTIKRMYRDDLGRFKEFKAQGVTIKFGKFSVKENQQLEKNVQEFLSLTGIENADKLLYTDRYPEEKSVITDLKRKYAFRVHIGKGIARPWKLVYYRAKKMFDVNNYKGRYSKGDTEKLKIYQSLHGNDWKKIGEMVSRSSLSVALKFSQINGQINHGAWSKTETQKLIKAVEEVILKKMSPQELNEMDSKLQLNPEGRLSIVREKLYKGISWVEVEARVETRNWMQCKSKWTEILTKRMTNGRDVYRGVNALQAKINLIERLYEINVQDVNEIDWEDLASIIGDVPPSYVQTKFYKLKATCVPFWQKKTFPEIIDYLYETSLPLLKEKLEKKMEKKGTEIQAPAAPKPVFLFRDIFYYDDDDSEGEDRDEKS", "length": 761, "header": "tr|F6QJN7-1|F6QJN7_BOVIN Isoform 1 of Transcription termination factor 1 OS=Bos taurus OX=9913 GN=TTF1 PE=4 SV=2 CANONICAL=F6QJN7-1" }, "locus": { "chromosome": "11", "start_pos": 102474993, "end_pos": 102451056, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000057042.3", "url": "https://www.ensembl.org/id/ENSBTAT00000057042.3" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000052612.3", "url": "https://www.ensembl.org/id/ENSBTAP00000052612.3" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [], "orthologs": [ { "uniprot_canonical_ac": "A0A286YBY6-1", "protein_name": "Transcription termination factor 1", "gene_name": "ttf1.5", "tax_id": 7955, "organism": "Danio rerio", "sequence": { "sequence": "MDEMPSLSSNDCNDRVGGKKVKKKKKRSKSTEQHELTESPQEQTEKRRKKKKRRNSIQETDSNLQTKKRRKLDKEGETSVMDDGVSNQHEEQTQELQGSREGKTSKRKKKREKLKQTQELQGSREGKTSKRKKKREKLKQTNCEDITKEQTDIRTEHEEEPNTSDPPDLIITDKKRESKTPKNNIDSKFMEELNEWVPKMKLRCKSYMNDIIRYELSRFKEFRKQGIEMRTGRFSTAENERLRQNVNNFMALTGVTDAVKLFFPSRYPKEANALRKLKKKHRFFESIADGIPRFCNDVYDRGARVYDDRNYKGHFSEEEVKLLLKYYKRYGRDFKKISDKTNRSCRSLESRLLFITERKGPWSSKEVQRLLRAVRDYVVSVLKSANPNQRKPKRVNKEILYKKLPWTKIAGQVKTRCWMTCKSKWMTILTARMSSGTTFRGRKSQEAKIKLIKAMYELQVEDAVDVPWEDLTAVFGDVLPSYVQSRWHKLKVNHVPDWKNKSFADIVDFLYENVLPGLVKDCEDLDDDELKVDQMNSFRLADIFQDINEDECCDSDEETGQQEKSSSA", "length": 568 }, "evidence": [ { "id": "F6QJN7", "url": "https://omabrowser.org/oma/group/F6QJN7/", "database": "OMA" } ], "glygen_name": "Zebrafish", "common_name": "Zebrafish" }, { "uniprot_canonical_ac": "D4A1Z7-1", "protein_name": "Transcription termination factor 1", "gene_name": "Ttf1", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MRSKTEVSTVFPPHNTSGLKDECYTISGMEGGKFKTHTATLHKKKKWSSVSEKRLQKWPSQHLESEQPQVSVRKKRRRESQTPAQESLESEQPWKAKKKKKRRRESQTPAQESLESEQTPMSMLGKRRRESQTPAQENLESEQPWKAKKKKRRREYQTPAEESLESEQPWKAKRKKKKEKESQQLTSSLLKNSETFHKAKKTTAAHKKKKNSVWEVDMETGIILVDKENMENLLETSRKDVDIVYVDMSKGQRSAKVNETEELPMAETQKRDCRELHSDIRSKKNQKHPQKIAPQDAIQGTQPERISLPQSESLSPVDLEGKNTKIAVFCKKKSKKKVFRSQELEAVSESLVSSETIPESLDSAHHGGEDETEEEGESIKESHRIRKKSKKKKHKSVTLATSGDSVSVLDSTAESALVDSPEGSGTLREEDVDHGSTEAEAQARPTEKHRKEIQRLEPTHEESNLESASNSATRCVSEDRRDSDESDVDLGSAVRQLQEFIPDIQERAATTIRRMYRDDLGRFKEFKAQGVAIRFGKFSVKENKQIEKNVQDFLSLTGIESADKLLYTDRYPEEKSLITNLKRKHAFRLHIGKGIARPWKLVYYRAKKIFDVNNYKGRYNEEDTKKLKAYHSLHGNDWKKIGAMVARSSLSVALKFSQIDGDRNHGTWSKAETQRLIKAVEDVILKKMSSQELRELDSRLQEDPEGRLSIVREKLYKGISWVEVEARVETRNWMQCKSKWTEILTKRMTHGGFVYRGVKALQAKITLIERLYELNVNDANEIDWEDLAGAIGDVPPPFVQAKFYKLKAACVPFWQKKTFPEIIDYLYENSLPLLKEKLAKKMKKKDSQIQKPTAPKQNFLFKDIFHCDDDSDEGGLEEPSTSDTQ", "length": 885 }, "evidence": [ { "id": "F6QJN7", "url": "https://omabrowser.org/oma/group/F6QJN7/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "Q15361-1", "protein_name": "Transcription termination factor 1", "gene_name": "TTF1", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MEGESSRFEIHTPVSDKKKKKCSIHKERPQKHSHEIFRDSSLVNEQSQITRRKKRKKDFQHLISSPLKKSRICDETANATSTLKKRKKRRYSALEVDEEAGVTVVLVDKENINNTPKHFRKDVDVVCVDMSIEQKLPRKPKTDKFQVLAKSHAHKSEALHSKVREKKNKKHQRKAASWESQRARDTLPQSESHQEESWLSVGPGGEITELPASAHKNKSKKKKKKSSNREYETLAMPEGSQAGREAGTDMQESQPTVGLDDETPQLLGPTHKKKSKKKKKKKSNHQEFEALAMPEGSQVGSEVGADMQESRPAVGLHGETAGIPAPAYKNKSKKKKKKSNHQEFEAVAMPESLESAYPEGSQVGSEVGTVEGSTALKGFKESNSTKKKSKKRKLTSVKRARVSGDDFSVPSKNSESTLFDSVEGDGAMMEEGVKSRPRQKKTQACLASKHVQEAPRLEPANEEHNVETAEDSEIRYLSADSGDADDSDADLGSAVKQLQEFIPNIKDRATSTIKRMYRDDLERFKEFKAQGVAIKFGKFSVKENKQLEKNVEDFLALTGIESADKLLYTDRYPEEKSVITNLKRRYSFRLHIGRNIARPWKLIYYRAKKMFDVNNYKGRYSEGDTEKLKMYHSLLGNDWKTIGEMVARSSLSVALKFSQISSQRNRGAWSKSETRKLIKAVEEVILKKMSPQELKEVDSKLQENPESCLSIVREKLYKGISWVEVEAKVQTRNWMQCKSKWTEILTKRMTNGRRIYYGMNALRAKVSLIERLYEINVEDTNEIDWEDLASAIGDVPPSYVQTKFSRLKAVYVPFWQKKTFPEIIDYLYETTLPLLKEKLEKMMEKKGTKIQTPAAPKQVFPFRDIFYYEDDSEGEDIEKESEGQAPCMAHACNSSTLGGQGRWII", "length": 905 }, "evidence": [ { "id": "F6QJN7", "url": "https://omabrowser.org/oma/group/F6QJN7/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "Q62187-1", "protein_name": "Transcription termination factor 1", "gene_name": "Ttf1", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MKGGTSKFKTHTETLYKKKKWSSVSEKRPQKCPSQCLESKQPQVSVLGKRRRASQTPAQETLESEWPQKAKRKKRRREPQTPAQETLESEWPQKAKKKKRRGEPQTPTQESLESEQPPVSLLGKRRRESQTPAQENSESEQPRKAKRRRKKRKGSQQPTSSLLKTPETFLKAKKTTSAHKKKKNSVLEVDMETGIILVDKENMENLLETSRKDVDIVYVDMSKGQRSAKVRETGELPAAKPQEHGCRELLGDVRSRKKQKHLQKVAPWDVVQGSQPESISLPPSEPLSSEDLEGKSTEAAVFCKKKSKKNVFRSQELEPIPDSLDDSETISERLDSTHHGGAVGAGEECESTKESHSIKKKSKKKKHKSVALATSSDSASVTDSKAKNALVDSSEGSGAVREEDVDHRPAEAEAQACSTEKHREAMQRLEPTHEEESNSESASNSAARHISEDRRESDDSDVDLGSAVRQLREFIPDIQERAATTIRRMYRDDLGRFKEFKAQGVAIRFGKFSAKENKQIEKNVQDFLSLTGIESADKLLYTDRYPEEKTLITNLKRKHAFRLHIGKGIARPWKLVYYRAKKIFDVNNYKGRYNEEDTKKLKAYHSLHGNDWKKIGAMVARSSLSVALKFSQIGGTRNQGAWSKAETQRLIKAVEDVILKKMSPQELRELDSKLQEDPEGRLSIVREKLYKGISWVEVEARVETRNWMQCKSKWTEILTKRMTHGGFVYRGVNALQAKITLIERLYELNVNDANEIDWEDLASAIGDVPPPFVQAKFYKLKAACVPFWQKKTFPEIIDYLYKNSLPLLKEKLDKKMKKKDGQIQTPAAPKQDFLFKDIFHCDDDSDEGSPEEPSASDVQ", "length": 859 }, "evidence": [ { "id": "F6QJN7", "url": "https://omabrowser.org/oma/group/F6QJN7/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q9FLM7-1", "protein_name": "Myb family transcription factor", "gene_name": "MEE6.9", "tax_id": 3702, "organism": "Arabidopsis thaliana", "sequence": { "sequence": "MAEEKKNKKKKSDAKVDSEETGEEFISEHSSMKDKEKKRKKNKRENKDGFTGEDMEITGRESEKLGDEVFIVKKKKKSKKPIRIDSEAVDAVKKKSKKRSKETKADSEAEDDGVEKKSKEKSKETKVDSEAHDGVKRKKKKSKKESGGDVIENTESSKVSDKKKGKRKRDDTDLGAEENIDKEVKRKNNKKKPSVDSDVEDINLDSTNDGKKKRKKKKQSEDSETEENGLNSTKDAKKRRKKKKKKKQSEVSEAEEKSDKSDEDLTTPSTSSKRVKFSDQVEFFPSDDDEGTEDDDEEEVKVVRGKRFTKEEDEMVKNAVLEYIDNHALGDEGIKMVMECKAYPQLKGCWKEITSALPWRTYNSVYHRAHTIFEAGSQGIWTKEDIELVMEFQKTHGNDWKTLADAMGKHRKHVKDAWRRGRLAGKKKGHWMREEYQNLFDLVNKDLRMKAFKEKHSKHGMLKDNIPWMAISDVLETRDHVTCCQKWYEQLISPMVAKGMWANVDDYRLLEELLKLDAACIDDVDWDNLLENRDGEACRKRWNQMIIHIGVPKSKTFAEQVEILSDRYCPDIAEDREDFDNRPYDPED", "length": 588 }, "evidence": [ { "id": "F6QJN7", "url": "https://omabrowser.org/oma/group/F6QJN7/", "database": "OMA" } ], "glygen_name": "Arabidopsis", "common_name": "Mouse-ear cress" } ], "go_annotation": { "categories": [ { "name": "Biological Process", "total": 1, "go_terms": [ { "name": "transcription by RNA polymerase I", "id": "GO:0006360", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006360", "evidence": [ { "database": "UniProtKB", "id": "F6QJN7", "url": "https://www.uniprot.org/uniprotkb/F6QJN7" } ], "pmid": "" } ] }, { "name": "Molecular Function", "total": 2, "go_terms": [ { "name": "DNA binding", "id": "GO:0003677", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003677", "evidence": [ { "database": "UniProtKB", "id": "F6QJN7", "url": "https://www.uniprot.org/uniprotkb/F6QJN7" } ], "pmid": "" }, { "name": "chromatin binding", "id": "GO:0003682", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003682", "evidence": [ { "database": "UniProtKB", "id": "F6QJN7", "url": "https://www.uniprot.org/uniprotkb/F6QJN7" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 2, "go_terms": [ { "name": "nucleoplasm", "id": "GO:0005654", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005654", "evidence": [ { "database": "UniProtKB", "id": "F6QJN7", "url": "https://www.uniprot.org/uniprotkb/F6QJN7" } ], "pmid": "" }, { "name": "fibrillar center", "id": "GO:0001650", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0001650", "evidence": [ { "database": "UniProtKB", "id": "F6QJN7", "url": "https://www.uniprot.org/uniprotkb/F6QJN7" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 152, "end_pos": 154, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "F6QJN7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F6QJN7" }, { "id": "PS50090", "database": "PROSITE", "url": "https://prosite.expasy.org/PS50090" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "Myb-like", "eco_id": "ECO_0000259", "start_pos": 540, "end_pos": 624, "start_aa": "Asn", "end_aa": "Leu", "glycosite_overlap": [] } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "homologset.oma", "label": "OMA Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 152, "end_pos": 154 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ], "tool_support": { "graph_view": "yes" } }, { "uniprot_canonical_ac": "G5E551-1", "uniprot_ac": "G5E551", "uniprot_id": "G5E551_BOVIN", "mass": { "chemical_mass": 96212.0, "monoisotopic_mass": 96212.0 }, "refseq": {}, "gene_names": [ { "name": "JAKMIP2", "type": "recommended", "evidence": [ { "id": "G5E551", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G5E551" } ] } ], "protein_names": [ { "name": "Janus kinase and microtubule interacting protein 2", "type": "synonym", "evidence": [ { "id": "G5E551", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G5E551/entry#names_and_taxonomy" } ] } ], "function": [], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Bos taurus", "taxid": 9913, "evidence": [ { "database": "UniProtKB", "id": "G5E551", "url": "https://www.uniprot.org/uniprotkb/G5E551" } ], "common_name": "Bovine", "glygen_name": "Bovine", "reference_species": "Bos taurus [9913]" } ], "gene": [ { "name": "JAKMIP2", "url": "https://www.uniprot.org/uniprotkb/G5E551", "locus": { "chromosome": "7", "start_pos": 58815877, "end_pos": 59006561, "strand": "+", "evidence": [ { "database": "Ensembl Gene", "id": "ENSBTAG00000003349", "url": "https://www.ensembl.org/id/ENSBTAG00000003349" } ] } } ], "crossref": [ { "id": "G5E551", "url": "https://alphafold.ebi.ac.uk/entry/G5E551", "database": "AlphaFoldDB", "categories": [] }, { "id": "ENSBTAG00000003349", "url": "https://bgee.org/?page=gene&gene_id=ENSBTAG00000003349", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "527239", "url": "https://www.ncbi.nlm.nih.gov/gene/527239", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR024836", "url": "https://www.ebi.ac.uk/interpro/entry/IPR024836", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR031994", "url": "https://www.ebi.ac.uk/interpro/entry/IPR031994", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "RNLELEX", "url": "https://omabrowser.org/oma/group/RNLELEX/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "A0A3Q1LQ17", "url": "https://www.orthodb.org/?gene=A0A3Q1LQ17", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A3Q1MXH9", "url": "https://www.orthodb.org/?gene=A0A3Q1MXH9", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A3Q1N956", "url": "https://www.orthodb.org/?gene=A0A3Q1N956", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A3Q1NL39", "url": "https://www.orthodb.org/?gene=A0A3Q1NL39", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "G5E551", "url": "https://www.orthodb.org/?gene=G5E551", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR18935", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR18935", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR18935:SF7", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR18935:SF7", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF16034", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF16034", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "A0A3Q1LQ17", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1LQ17", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A3Q1LQ17-1", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1LQ17-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A3Q1MXH9", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1MXH9", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A3Q1MXH9-1", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1MXH9-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A3Q1N956", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1N956", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A3Q1N956-1", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1N956-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A3Q1NL39", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1NL39", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A3Q1NL39-1", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1NL39-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0AAA9SUL5", "url": "https://www.uniprot.org/uniprotkb/A0AAA9SUL5", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0AAA9SUL5-1", "url": "https://www.uniprot.org/uniprotkb/A0AAA9SUL5-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "G5E551", "url": "https://www.uniprot.org/uniprotkb/G5E551", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "G5E551-1", "url": "https://www.uniprot.org/uniprotkb/G5E551-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MSKKGRNKGEKPEALIVALQAANEDLRTKLTDIQIELHQEKSKVSKLEREKTQEAKRIRELEQRKHTVLVTELKAKLHEEKMKELQAVRENLIKQHEQEMARTVKVRDGEIQRLKSALCALRDGSSDKVRTALTIEAREEARKLFDAERLKLLQEIADLKTAKKQVDEALSNMIQADKIKAGDLRSEHQSHQEAISKIKWESERDIRRLMDEIKAKDRIIFSLEKELETQTGYVQKLQLQKEALDEQLFLVKEAECNMSSPKREIPGRAGDGSEHCSSPDLRRNQKRIAELNATIRKLEDRNTLLGDERNELLKRVRETEKQCKPLLERNKCLAKRNDELMVSLQRMEEKLKAVTKENSEMREKITSHPPLKKLKSLNDLDQANEEQETEFLKLQVIEQQNIIDELTRDREKLIRRRKHRRSSKPIKRPVLDPFIGYDEDSMDSETSSMASFRTDRTPATPDDDLDESLAAEESELRFRQLTKEYQALQRAYALLQEQTGGIIDAEREAKAQEQLQAEVLRYKAKIEDLEATLAQKGQDSHWVEDKQLFIKRNQELLEKIEKQEAENHRLQQELQDARDQNELLEFRNLELEERERRSPPFNLQIHPFSDGVSALQIYCMKEGVKDVNIPDLIKQLDILGDNGNLRNEEQVAIIQASTVLSLAEKWIQQIEGAEAALHQKMMELESDMEQFCKIKGYLEEELDYRKQALDQAYMRIQELEATLYNALQQETVIKFGELLSEKQQEELRTAVEKLRRQMLRKSREYDCQILQERMELLQQAHQRIRDLEDKTDIQKRQIKDLEEKFLFLFLFFSLAFILWP", "length": 820, "header": "tr|G5E551-1|G5E551_BOVIN Isoform 1 of Janus kinase and microtubule interacting protein 2 OS=Bos taurus OX=9913 GN=JAKMIP2 PE=3 SV=1 CANONICAL=G5E551-1" }, "isoforms": [ { "isoform_ac": "A0A3Q1LQ17-1", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1LQ17/entry", "sequence": { "sequence": "MVSKLEREKTQEAKRIRELEQRKHTVLVTELKAKLHEEKMKELQAVRENLIKQHEQEMARTVKVRDGEIQRLKSALCALRDGSSDKVRTALTIEAREEARKLFDAERLKLLQEIADLKTAKKQVDEALSNMIQADKIKAGDLRSEHQSHQEAISKIKWESERDIRRLMDEIKAKDRIIFSLEKELETQTGYVQKLQLQKEALDEQLFLVKEAECNMSSPKREIPGRAGDGSEHCSSPDLRRNQKRIAELNATIRKLEDRNTLLGDERNELLKRVRETEKQCKPLLERNKCLAKRNDELMVSLQRMEEKLKAVTKENSEMREKITSHPPLKKLKSLNDLDQANEEQETEFLKLQVIEQQNIIDELTRDREKLIRRRKHRRSSKPIKRPVLDPFIGYDEDSMDSETSSMASFRTDRTPATPDDDLDESLAAEESELRFRQLTKEYQALQRAYALLQEQTGGIIDAEREAKAQEQLQAEVLRYKAKIEDLEATLAQKGQDSHWVEDKQLFIKRNQELLEKIEKQEAENHRLQQELQDARDQNELLEFRNLELEERERRSPPFNLQIHPFSDGVSALQIYCMKEGVKDVNIPDLIKQLDILGDNGNLRNEEQVAIIQASTVLSLAEKWIQQIEGAEAALHQKMMELESDMEQFCKIKGYLEEELDYRKQALDQAYMRIQELEATLYNALQQETVIKFGELLSEKQQEELRTAVEKLRRQMLRKSREYDCQILQERMELLQQAHQRIRDLEDKTDIQKRQIKDLEEKFLFLFLFFSLAFILWP", "length": 778, "header": "tr|A0A3Q1LQ17-1|G5E551_BOVIN Computationally mapped isoform of Janus kinase and microtubule interacting protein 2 OS=Bos taurus OX=9913 GN=JAKMIP2 PE=3 SV=2 CANONICAL=G5E551-1" }, "locus": { "chromosome": "7", "start_pos": 59006318, "end_pos": 58824069, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000076712.2", "url": "https://www.ensembl.org/id/ENSBTAT00000076712.2" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000059057.2", "url": "https://www.ensembl.org/id/ENSBTAP00000059057.2" } ] } }, { "isoform_ac": "A0A3Q1MXH9-1", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1MXH9/entry", "sequence": { "sequence": "MSKKGRNKGEKPEALIVALQAANEDLRTKLTDIQIELHQEKSKVSKLEREKTQEAKRIRELEQRKHTVLVTELKAKLHEEKMKELQAVRENLIKQHEQEMARTVKVRDGEIQRLKSALCALRDGSSDKVRTALTIEAREEARKLFDAERLKLLQEIADLKTAKKQVDEALSNMIQADKIKAGDLRSEHQSHQEAISKIKWESERDIRRLMDEIKAKDRIIFSLEKELETQTGYVQKLQLQKEALDEQLFLVKEAECNMSSPKREIPGRAGDGSEHCSSPDLRRNQKRIAELNATIRKLEDRNTLLGDERNELLKRVRETEKQCKPLLERNKCLAKRNDELMVSLQRMEEKLKAVTKENSEMREKITSHPPLKKLKSLNDLDQANEEQETEFLKLQVIEQQNIIDELTRDREKLIRRRKHRRSSKPIKRPVLDPFIGYDEDSMDSETSSMASFRTDRTPATPDDDLDESLAAEESELRFRQLTKEYQALQRAYALLQEQTGGIIDAEREAKAQEQLQAEVLRYKAKIEDLEATLAQKGQDSHWVEDKQLFIKRNQELLEKIEKQEAENHRLQQELQDARDQNELLEFRNLELEERERRSPPFNLQIHPFSDGVSALQIYCMKEGVKDVNIPDLIKQLDILGDNGNLRNEEQVAIIQASTVLSLAEKWIQQIEGAEAALHQKMMELESDMEQFCKIKGYLEEELDYRKQALDQAYMRIQELEATLYNALQQETVIKFGELLSEKQQEELRTAVEKLRRQMLRKSREYDCQILQERMELLQQAHQRIRDLEDKTDIQKRQIKDLEEKWS", "length": 806, "header": "tr|A0A3Q1MXH9-1|G5E551_BOVIN Computationally mapped isoform of Janus kinase and microtubule interacting protein 2 OS=Bos taurus OX=9913 GN=JAKMIP2 PE=3 SV=2 CANONICAL=G5E551-1" }, "locus": { "chromosome": "7", "start_pos": 58883768, "end_pos": 58827110, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000071435.2", "url": "https://www.ensembl.org/id/ENSBTAT00000071435.2" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000060438.2", "url": "https://www.ensembl.org/id/ENSBTAP00000060438.2" } ] } }, { "isoform_ac": "A0A3Q1N956-1", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1N956/entry", "sequence": { "sequence": "MSKKGRNKGEKPEALIVALQAANEDLRTKLTDIQIELHQEKSKVSKLEREKTQEAKRIRELEQRKHTVLVTELKAKLHEEKMKELQAVRENLIKQHEQEMARTVKVRDGEIQRLKSALCALRDGSSDKVRTALTIEAREEARKLFDAERLKLLQEIADLKTAKKQVDEALSNMIQADKIKAGDLRSEHQSHQEAISKIKWESERDIRRLMDEIKAKDRIIFSLEKELETQTGYVQKLQLQKEALDEQLFLVKEAECNMSSPKREIPGRAGDGSEHCSSPDLRRNQKRIAELNATIRKLEDRNTLLGDERNELLKRVRETEKQCKPLLERNKCLAKRNDELMVSLQRMEEKLKAVTKENSEMREKITSHPPLKKLKSLNDLDQANEEQETEFLKLQVIEQQNIIDELTRDREKLIRRRKHRRSSKPIKRPVLDPFIGYDEDSMDSETSSMASFRTDRTPATPDDDLDESLAAEESELRFRQLTKEYQALQRAYALLQEQTGGIIDAEREAKAQEQLQAEVLRYKAKIEDLEATLAQKGQDSHWVEDKQLFIKRNQELLEKIEKQEAENHRLQQELQDARDQNELLEFRNLELEERERRSPPFNLQIHPFSDGVSALQIYCMKEGVKDVNIPDLIKQLDILGDNGNLRNEEQVAIIQASTVLSLAEKWIQQIEGAEAALHQKMMELESDMEQFCKIKGYLEEELDYRKQALDQAYMRIQELEATLYNALQQETVIKFGELLSEKQQEELRTAVEKLRRQMLRKSREYDCQILQERMELLQQAHQRIRDLEDKTDIQKRQIKDLEEKECPPWISNHMFTLQISVSILVLLSCLYSMALMSRCLLQRNRKHG", "length": 848, "header": "tr|A0A3Q1N956-1|G5E551_BOVIN Computationally mapped isoform of Janus kinase and microtubule interacting protein 2 OS=Bos taurus OX=9913 GN=JAKMIP2 PE=3 SV=2 CANONICAL=G5E551-1" }, "locus": { "chromosome": "7", "start_pos": 58883768, "end_pos": 58816881, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000082033.2", "url": "https://www.ensembl.org/id/ENSBTAT00000082033.2" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000067655.2", "url": "https://www.ensembl.org/id/ENSBTAP00000067655.2" } ] } }, { "isoform_ac": "A0A3Q1NL39-1", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1NL39/entry", "sequence": { "sequence": "MSKKGRNKGEKPEALIVALQAANEDLRTKLTDIQIELHQEKSKVSKLEREKTQEAKRIRELEQRKHTVLVTELKAKLHEEKMKELQAVRENLIKQHEQEMARTVKVRDGEIQRLKSALCALRDGSSDKVRTALTIEAREEARKLFDAERLKLLQEIADLKTAKKQVDEALSNMIQADKIKAGDLRSEHQSHQEAISKIKWESERDIRRLMDEIKAKDRIIFSLEKELETQTGYVQKLQLQKEALDEQLFLVKEAECNMSSPKREIPGRAGDGSEHCSSPDLRRNQKRIAELNATIRKLEDRNTLLGDERNELLKRVRETEKQCKPLLERNKCLAKRNDELMVSLQRMEEKLKAVTKENSEMREKITSHPPLKKLKSLNDLDQANEEQETEFLKLQVIEQQNIIDELTRDREKLIRRRKHRRSSKPIKRPVLDPFIGYDEDSMDSETSSMASFRTDRTPATPDDDLDESLAAEESELRFRQLTKEYQALQRAYALLQEQTGGIIDAEREAKAQEQLQAEVLRYKAKIEDLEATLAQKGQIEKQEAENHRLQQELQDARDQNELLEFRNLELEERERRSPPFNLQIHPFSDGVSALQIYCMKEGVKDVNIPDLIKQLDILGDNGNLRNEEQVAIIQASTVLSLAEKWIQQIEGAEAALHQKMMELESDMEQFCKIKGYLEEELDYRKQALDQAYMRIQELEATLYNALQQETVIKFGELLSEKQQEELRTAVEKLRRQMLRKSREYDCQILQERMELLQQAHQRIRDLEDKTDIQKRQIKDLEEKFLFLFLFFSLAFILWP", "length": 799, "header": "tr|A0A3Q1NL39-1|G5E551_BOVIN Computationally mapped isoform of Janus kinase and microtubule interacting protein 2 OS=Bos taurus OX=9913 GN=JAKMIP2 PE=3 SV=1 CANONICAL=G5E551-1" }, "locus": { "chromosome": "7", "start_pos": 58883768, "end_pos": 58824069, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000072239.2", "url": "https://www.ensembl.org/id/ENSBTAT00000072239.2" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000073097.1", "url": "https://www.ensembl.org/id/ENSBTAP00000073097.1" } ] } }, { "isoform_ac": "A0AAA9SUL5-1", "url": "https://www.uniprot.org/uniprotkb/A0AAA9SUL5/entry", "sequence": { "sequence": "MSKKGRNKGEKPEALIVALQAANEDLRTKLTDIQIELHQEKSKVSKLEREKTQEAKRIRELEQRKHTVLVTELKAKLHEEKMKELQAVRENLIKQHEQEMARTVKVRDGEIQRLKSALCALRDGSSDKVRTALTIEAREEARKLFDAERLKLLQEIADLKTAKKQVDEALSNMIQADKIKAGDLRSEHQSHQEAISKIKWESERDIRRLMDEIKAKDRIIFSLEKELETQTGYVQKLQLQKEALDEQLFLVKEAECNMSSPKREIPGRAGDGSEHCSSPDLRRNQKRIAELNATIRKLEDRNTLLGDERNELLKRVRETEKQCKPLLERNKCLAKRNDELMVSLQRMEEKLKAVTKENSEMREKITSHPPLKKLKSLNDLDQANEEQETEFLKLQVIEQQNIIDELTRDREKLIRRRKHRRSSKPIKRPVLDPFIGYDEDSMDSETSSMASFRTDRTPATPDDDLDESLAAEESELRFRQLTKEYQALQRAYALLQEQTGGIIDAEREAKAQEQLQAEVLRYKAKIEDLEATLAQKGQDSHWVEDKQLFIKRNQELLEKIEKQEAENHRLQQELQDARDQNELLEFRNLELEERERRSPPFNLQIHPFSDGVSALQIYCMKEGVKDVNIPDLIKQLDILGDNGNLRNEEQVAIIQASTVLSLAEKWIQQIEGAEAALHQKMMELESDMEQFCKIKGYLEEELDYRKQALDQAYMRIQELEATLYNALQQETVIKFGELLSEKQQEELRTAVEKLRRQMLRKSREYDCQILQERMELLQQAHQRIRDLEDKTDIQKRQIKDLEEKRNRKHG", "length": 810, "header": "tr|A0AAA9SUL5-1|G5E551_BOVIN Computationally mapped isoform of Janus kinase and microtubule interacting protein 2 OS=Bos taurus OX=9913 GN=JAKMIP2 PE=3 SV=1 CANONICAL=G5E551-1" }, "locus": { "chromosome": "7", "start_pos": 58883768, "end_pos": 58816881, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000109437.1", "url": "https://www.ensembl.org/id/ENSBTAT00000109437.1" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000090148.1", "url": "https://www.ensembl.org/id/ENSBTAP00000090148.1" } ] } }, { "isoform_ac": "G5E551-1", "url": "https://www.uniprot.org/uniprotkb/G5E551/entry", "sequence": { "sequence": "MSKKGRNKGEKPEALIVALQAANEDLRTKLTDIQIELHQEKSKVSKLEREKTQEAKRIRELEQRKHTVLVTELKAKLHEEKMKELQAVRENLIKQHEQEMARTVKVRDGEIQRLKSALCALRDGSSDKVRTALTIEAREEARKLFDAERLKLLQEIADLKTAKKQVDEALSNMIQADKIKAGDLRSEHQSHQEAISKIKWESERDIRRLMDEIKAKDRIIFSLEKELETQTGYVQKLQLQKEALDEQLFLVKEAECNMSSPKREIPGRAGDGSEHCSSPDLRRNQKRIAELNATIRKLEDRNTLLGDERNELLKRVRETEKQCKPLLERNKCLAKRNDELMVSLQRMEEKLKAVTKENSEMREKITSHPPLKKLKSLNDLDQANEEQETEFLKLQVIEQQNIIDELTRDREKLIRRRKHRRSSKPIKRPVLDPFIGYDEDSMDSETSSMASFRTDRTPATPDDDLDESLAAEESELRFRQLTKEYQALQRAYALLQEQTGGIIDAEREAKAQEQLQAEVLRYKAKIEDLEATLAQKGQDSHWVEDKQLFIKRNQELLEKIEKQEAENHRLQQELQDARDQNELLEFRNLELEERERRSPPFNLQIHPFSDGVSALQIYCMKEGVKDVNIPDLIKQLDILGDNGNLRNEEQVAIIQASTVLSLAEKWIQQIEGAEAALHQKMMELESDMEQFCKIKGYLEEELDYRKQALDQAYMRIQELEATLYNALQQETVIKFGELLSEKQQEELRTAVEKLRRQMLRKSREYDCQILQERMELLQQAHQRIRDLEDKTDIQKRQIKDLEEKFLFLFLFFSLAFILWP", "length": 820, "header": "tr|G5E551-1|G5E551_BOVIN Isoform 1 of Janus kinase and microtubule interacting protein 2 OS=Bos taurus OX=9913 GN=JAKMIP2 PE=3 SV=1 CANONICAL=G5E551-1" }, "locus": { "chromosome": "7", "start_pos": 58883768, "end_pos": 58824069, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000004348.5", "url": "https://www.ensembl.org/id/ENSBTAT00000004348.5" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000004348.4", "url": "https://www.ensembl.org/id/ENSBTAP00000004348.4" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [], "orthologs": [ { "uniprot_canonical_ac": "A0A8I6A3T9-1", "protein_name": "Janus kinase and microtubule interacting protein 2", "gene_name": "Jakmip2", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MSKKGRNKGEKPEALIVALQAANEDLRTKLTDIQIELHQEKSKVSKLEREKTQEAKRIRELEQRKHTVLVTELKAKLHEEKMKELQAVRENLIKQHEQEMSRTVKVRDGEIQRLKSALCALRDGSSDKVRTALTIEAREEARKQFDAERLKLLQEITDLKTAKKQVDEALSNMIQADKIKAGDLRSEHQSHQEAISKIKWESERDIRRLMDEIKAKDRIIFSLEKELETQTGYVQKLQLQKEALDEQLFLVKEAECNMSSPKREIPGRAGDGSEHCSSPDLRRNQKRIAELNATIRKLEDRNTLLGDERNELLKRVRETEKQCKPLLERNKCLAKRNDELMVSLQRMEEKLKAITKENSEMREKITSHPPLKKLKSLNDLDQANEEQETEFLKLQVIEQQNIIDELTRDREKLIRRRKHRRSSKPIKRPVLDPFIGYDEDSMDSETSSMTSFRTDRTPATPDDDLDESLAAEESELRFRQLTKEYQALQRAYALLQEQTGGIIDAEREAKAQEQLQAEVLRYRAKIEDLEATLAQKGQDSHWVEDKQLFIKRNQELLEKIEKQEAENHRLQQELQDARDQNELLEFRNLELEERERRSPPFNLQIHPFSDGVSALQIYCMKEGVKDVNIPDLIKQLDILGDNGNLRNEEQVAIIQASTVLSLAEKWIQQIEGAEAALHQKMMELESDMEQFCKIKGYLEEELDYRKQALDQAYMRIQELEATLYNALQQETVIKFGELLSDKQQEELRTAVEKLRRQMLRKSREYDCQILQERMELLQQAHQRIRDLEDKTDIQKRQIKDLEEKFLFLFLFFSLAFILWP", "length": 820 }, "evidence": [ { "id": "G5E551", "url": "https://omabrowser.org/oma/group/G5E551/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "D3YXK0-1", "protein_name": "Janus kinase and microtubule interacting protein 2", "gene_name": "Jakmip2", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MSKKGRNKGEKPEALIVALQAANEDLRTKLTDIQIELHQEKSKVSKLEREKTQEAKRIRELEQRKHTVLVTELKAKLHEEKMKELQAVRENLIKQHEQEMSRTVKVRDGEIQRLKSALCALRDGSSDKVRTALTIEAREEARKQFDAERLKLLQEITDLKTAKKQVDEALSNMIQADKIKAGDLRSEHQSHQEAISKIKWESERDIRRLMDEIKAKDRIIFSLEKELETQTGYVQKLQLQKEALDEQLFLVKEAECNMSSPKREIPGRAGDGSEHCSSPDLRRNQKRIAELNATIRKLEDRNTLLGDERNELLKRVRETEKQCKPLLERNKCLAKRNDELMVSLQRMEEKLKAVTKENSEMREKITSHPPLKKLKSLNDLDQANEEQETEFLKLQVIEQQNIIDELTRDREKLIRRRKHRRSSKPIKRPVLDPFIGYDEDSMDSETSSMTSFRTDRTPATPDDDLDESLAAEESELRFRQLTKEYQALQRAYALLQEQTGGIIDAEREAKAQEQLQAEVLRYRAKIEDLEATLAQKGQDSHWVEDKQLFIKRNQELLEKIEKQEAENHRLQQELQDARDQNELLEFRNLELEERERRSPPFNLQIHPFSDGVSALQIYCMKEGVKDVNIPDLIKQLDILGDNGNLRNEEQVAIIQASTVLSLAEKWIQQIEGAEAALHQKMMELESDMEQFCKIKGYLEEELDYRKQALDQAYMRIQELEATLYNALQQETVIKFGELLSDKQQEELRTAVEKLRRQMLRKSREYDCQILQERMELLQQAHQRIRDLEDKTDIQKRQIKDLEEKFLFLFLFFSLAFILWP", "length": 820 }, "evidence": [ { "id": "G5E551", "url": "https://omabrowser.org/oma/group/G5E551/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "E1BZS6-1", "protein_name": "Janus kinase and microtubule interacting protein 2", "gene_name": "JAKMIP2", "tax_id": 9031, "organism": "Gallus gallus", "sequence": { "sequence": "MSKKGRSKGEKPEALIVALQAANEELRTKLTDIQIELHQEKSKIAKLEREKTQETKRIREVEQRKQTVQITELKAKLHEEKMKELQAVRENLIKQHEQEMTRMVKVRDSEIQRLKSALCALRDGSSDKVRTALTIEAREEARKQFDSERLKLLQEITELKSAKKQVDEALNNMIQADKIKAGDLRSEHQSHQEAISKIKWESERDIRRLMDEIKAKDRIIFSLEKELETQTGYVQKLQLQKEALDEQLFLVKEAECNMSSPKREIPGRAGDGSEHCSSPDLRRNQKRIAELNATIRKLEDRNTLLVDERNELLKRVREAEKQCKPLLEKNKCLTKRNDELMQSLQRIEDKLKAVTKENIEMREKMTSHPPLKKLKSLNDLDQANEEQETEFLKLQVIEQQNIIDELTRDREKLIRRRRSKRSSKPIKRHVIDAVMGYDDDSMDSETSSVASYRTDRTPATPDDDLDESLAAEESELRFRQLTKEYQALQRAYALLQEQTGGVIDAEREAKAQEQLQAEVQRYKAKIEDLEKTLAQKGQDSHWVEDKQLFIKRNQELLDKIEKLEAENNRLQQELQDARDQNELLEFRNLELEERERRSPPFNLQIHPFSDGVSALQIYCMKEGVKDVSIPDLIKQLDILGDNGNLRNEEQVAIIQASTVLSLAEKWIQQIEGAEAALHQKMMELESDMEQFCKIKGYLEEELDYRKQALDQAYMRIQELEATLYNALQQETVIKFGELLTEKQQEELRTAVEKLRRQMLRKSREYDCQILQERMELLQQAHQRIRDLEDKTDIQKRQIKDLEEKFLFLFLFFSLAFILWP", "length": 820 }, "evidence": [ { "id": "G5E551", "url": "https://omabrowser.org/oma/group/G5E551/", "database": "OMA" } ], "glygen_name": "Chicken", "common_name": "Chicken" }, { "uniprot_canonical_ac": "Q96AA8-1", "protein_name": "Janus kinase and microtubule-interacting protein 2", "gene_name": "JAKMIP2", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MSKKGRNKGEKPEALIVALQAANEDLRTKLTDIQIELHQEKSKVSKLEREKTQEAKRIRELEQRKHTVLVTELKAKLHEEKMKELQAVRENLIKQHEQEMSRTVKVRDGEIQRLKSALCALRDGSSDKVRTALTIEAREEARKLFDTERLKLLQEIADLKTAKKQVDEALSNMIQADKIKAGDLRSEHQSHQEAISKIKWESERDIRRLMDEIKAKDRIIFSLEKELETQTGYVQKLQLQKEALDEQLFLVKEAECNMSSPKREIPGRAGDGSEHCSSPDLRRNQKRIAELNATIRKLEDRNTLLGDERNELLKRVRETEKQCKPLLERNKCLAKRNDELMVSLQRMEEKLKAVTKENSEMREKITSHPPLKKLKSLNDLDQANEEQETEFLKLQVIEQQNIIDELTRDREKLIRRRKHRRSSKPIKRPVLDPFIGYDEDSMDSETSSMASFRTDRTPATPDDDLDESLAAEESELRFRQLTKEYQALQRAYALLQEQTGGIIDAEREAKAQEQLQAEVLRYKAKIEDLEATLAQKGQDSHWVEDKQLFIKRNQELLEKIEKQEAENHRLQQELQDARDQNELLEFRNLELEERERRSPPFNLQIHPFSDGVSALQIYCMKEGVKDVNIPDLIKQLDILGDNGNLRNEEQVAIIQASTVLSLAEKWIQQIEGAEAALHQKMMELESDMEQFCKIKGYLEEELDYRKQALDQAYMRIQELEATLYNALQQETVIKFGELLSEKQQEELRTAVEKLRRQMLRKSREYDCQILQERMELLQQAHQRIRDLEDKTDIQKRQIKDLEEKSNRKHG", "length": 810 }, "evidence": [ { "id": "G5E551", "url": "https://omabrowser.org/oma/group/G5E551/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" } ], "go_annotation": { "categories": [ { "name": "Molecular Function", "total": 2, "go_terms": [ { "name": "microtubule binding", "id": "GO:0008017", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008017", "evidence": [ { "database": "UniProtKB", "id": "G5E551", "url": "https://www.uniprot.org/uniprotkb/G5E551" } ], "pmid": "" }, { "name": "kinase binding", "id": "GO:0019900", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0019900", "evidence": [ { "database": "UniProtKB", "id": "G5E551", "url": "https://www.uniprot.org/uniprotkb/G5E551" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 1, "go_terms": [ { "name": "Golgi apparatus", "id": "GO:0005794", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005794", "evidence": [ { "database": "UniProtKB", "id": "G5E551", "url": "https://www.uniprot.org/uniprotkb/G5E551" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 257, "end_pos": 259, "annotation": "n_glycosylation_sequon" }, { "start_pos": 292, "end_pos": 294, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "G5E551", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G5E551" }, { "id": "PF16034", "database": "Pfam", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF16034" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "Janus kinase and microtubule-interacting protein C-terminal", "eco_id": "ECO_0000259", "start_pos": 409, "end_pos": 602, "start_aa": "Asp", "end_aa": "Asn", "glycosite_overlap": [] } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" }, { "name": "homologset.oma", "label": "OMA Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 257, "end_pos": 259 }, { "start_pos": 292, "end_pos": 294 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ], "tool_support": { "graph_view": "yes" } }, { "uniprot_canonical_ac": "F6S0F4-1", "uniprot_ac": "F6S0F4", "uniprot_id": "F6S0F4_BOVIN", "mass": { "chemical_mass": 25137.0, "monoisotopic_mass": 25137.0 }, "refseq": { "ac": "XP_005213397", "name": "sperm acrosome-associated protein 9 isoform X1", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_005213397" }, "gene_names": [ { "name": "SPACA9", "type": "recommended", "evidence": [ { "id": "F6S0F4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F6S0F4" } ] }, { "name": "C11H9orf9", "type": "synonym", "evidence": [ { "id": "XP_005213397", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_005213397" } ] }, { "name": "SPACA9", "type": "synonym", "evidence": [ { "id": "XP_005213397", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_005213397" } ] } ], "protein_names": [ { "name": "Sperm acrosome associated 9", "type": "synonym", "evidence": [ { "id": "F6S0F4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F6S0F4/entry#names_and_taxonomy" } ] }, { "name": "sperm acrosome-associated protein 9 isoform X1", "type": "synonym", "evidence": [ { "id": "XP_005213397", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_005213397" } ] } ], "function": [], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Bos taurus", "taxid": 9913, "evidence": [ { "database": "UniProtKB", "id": "F6S0F4", "url": "https://www.uniprot.org/uniprotkb/F6S0F4" } ], "common_name": "Bovine", "glygen_name": "Bovine", "reference_species": "Bos taurus [9913]" } ], "gene": [ { "name": "SPACA9", "url": "https://www.uniprot.org/uniprotkb/F6S0F4", "locus": { "chromosome": "11", "start_pos": 102922855, "end_pos": 102911379, "strand": "-", "evidence": [ { "database": "Ensembl Gene", "id": "ENSBTAG00000005189", "url": "https://www.ensembl.org/id/ENSBTAG00000005189" } ] } } ], "crossref": [ { "id": "F6S0F4", "url": "https://alphafold.ebi.ac.uk/entry/F6S0F4", "database": "AlphaFoldDB", "categories": [] }, { "id": "ENSBTAG00000005189", "url": "https://bgee.org/?page=gene&gene_id=ENSBTAG00000005189", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "539447", "url": "https://www.ncbi.nlm.nih.gov/gene/539447", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "8OTZ", "url": "https://www.ncbi.nlm.nih.gov/Structure/icn3d/?mmdbid=8OTZ&bu=0", "database": "iCn3D", "categories": [ "3D Structure" ] }, { "id": "8OU0", "url": "https://www.ncbi.nlm.nih.gov/Structure/icn3d/?mmdbid=8OU0&bu=0", "database": "iCn3D", "categories": [ "3D Structure" ] }, { "id": "9CPB", "url": "https://www.ncbi.nlm.nih.gov/Structure/icn3d/?mmdbid=9CPB&bu=0", "database": "iCn3D", "categories": [ "3D Structure" ] }, { "id": "9FQR", "url": "https://www.ncbi.nlm.nih.gov/Structure/icn3d/?mmdbid=9FQR&bu=0", "database": "iCn3D", "categories": [ "3D Structure" ] }, { "id": "IPR027818", "url": "https://www.ebi.ac.uk/interpro/entry/IPR027818", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "EHHCYNS", "url": "https://omabrowser.org/oma/group/EHHCYNS/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "A0A3Q1MYU9", "url": "https://www.orthodb.org/?gene=A0A3Q1MYU9", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR32455", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR32455", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR32455:SF1", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR32455:SF1", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "pdb_00008otz", "url": "https://www.rcsb.org/structure/pdb_00008otz", "database": "PDB", "categories": [ "3D Structure" ] }, { "id": "pdb_00008ou0", "url": "https://www.rcsb.org/structure/pdb_00008ou0", "database": "PDB", "categories": [ "3D Structure" ] }, { "id": "pdb_00009cpb", "url": "https://www.rcsb.org/structure/pdb_00009cpb", "database": "PDB", "categories": [ "3D Structure" ] }, { "id": "pdb_00009fqr", "url": "https://www.rcsb.org/structure/pdb_00009fqr", "database": "PDB", "categories": [ "3D Structure" ] }, { "id": "8OTZ", "url": "https://www.rcsb.org/structure/8OTZ", "database": "PDB", "categories": [ "3D Structure" ] }, { "id": "8OU0", "url": "https://www.rcsb.org/structure/8OU0", "database": "PDB", "categories": [ "3D Structure" ] }, { "id": "9CPB", "url": "https://www.rcsb.org/structure/9CPB", "database": "PDB", "categories": [ "3D Structure" ] }, { "id": "9FQR", "url": "https://www.rcsb.org/structure/9FQR", "database": "PDB", "categories": [ "3D Structure" ] }, { "id": "PF15120", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF15120", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "XP_005213397", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_005213397", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A3Q1MYU9", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1MYU9", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A3Q1MYU9-1", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1MYU9-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "F6S0F4", "url": "https://www.uniprot.org/uniprotkb/F6S0F4", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "F6S0F4-1", "url": "https://www.uniprot.org/uniprotkb/F6S0F4-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MMNEVKESLRSVEQKYKIFQQQQFTFIGALEHCRENAHDKIRPISSIGQVQSYMEHHCSNSTDRRILLMFLDICSELSKLCQHFEALHAGTPVTNNLLEKCKTLVSQSNDLSSLRAKYPHDVVNHLSCDEARNHYGGVVSLIPIILDLMKEWVAHSEKLPRKALQQVSEPQAATRATAHAPQASGTQPQLRKQNCGQLIQNIPKPGGKDQGSSKPPWRPPGGKL", "length": 224, "header": "tr|F6S0F4-1|F6S0F4_BOVIN Isoform 1 of Sperm acrosome associated 9 OS=Bos taurus OX=9913 GN=SPACA9 PE=4 SV=1 CANONICAL=F6S0F4-1" }, "isoforms": [ { "isoform_ac": "A0A3Q1MYU9-1", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1MYU9/entry", "sequence": { "sequence": "MMNEVKESLRSVEQKYKIFQQQQFTFIGALEHCRENAHDKIRPISSIGQVQSYMEHHCSNSTDRRILLMFLDICSELSKLCQHFEALHAGTPVTNNLLEKCKTLVSQSNDLSSLRAKYPHDVVNHLSCDEARNHYGGVVSLIPIILDLMKEWVAHSEKLPRKALQQGAT", "length": 169, "header": "tr|A0A3Q1MYU9-1|F6S0F4_BOVIN Computationally mapped isoform of Sperm acrosome associated 9 OS=Bos taurus OX=9913 GN=SPACA9 PE=4 SV=2 CANONICAL=F6S0F4-1" }, "locus": { "chromosome": "11", "start_pos": 102922477, "end_pos": 102917783, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000069693.3", "url": "https://www.ensembl.org/id/ENSBTAT00000069693.3" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000061283.2", "url": "https://www.ensembl.org/id/ENSBTAP00000061283.2" } ] } }, { "isoform_ac": "F6S0F4-1", "url": "https://www.uniprot.org/uniprotkb/F6S0F4/entry", "sequence": { "sequence": "MMNEVKESLRSVEQKYKIFQQQQFTFIGALEHCRENAHDKIRPISSIGQVQSYMEHHCSNSTDRRILLMFLDICSELSKLCQHFEALHAGTPVTNNLLEKCKTLVSQSNDLSSLRAKYPHDVVNHLSCDEARNHYGGVVSLIPIILDLMKEWVAHSEKLPRKALQQVSEPQAATRATAHAPQASGTQPQLRKQNCGQLIQNIPKPGGKDQGSSKPPWRPPGGKL", "length": 224, "header": "tr|F6S0F4-1|F6S0F4_BOVIN Isoform 1 of Sperm acrosome associated 9 OS=Bos taurus OX=9913 GN=SPACA9 PE=4 SV=1 CANONICAL=F6S0F4-1" }, "locus": { "chromosome": "11", "start_pos": 102921840, "end_pos": 102917783, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000006841.4", "url": "https://www.ensembl.org/id/ENSBTAT00000006841.4" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000006841.3", "url": "https://www.ensembl.org/id/ENSBTAP00000006841.3" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [ { "title": "Structural specializations of the sperm tail.", "journal": "Cell", "date": "2023", "authors": "Leung Miguel Ricardo, Zeng Jianwei, Wang Xiangli, Roelofs Marc C, Huang Wei, Zenezini Chiozzi Riccardo, Hevler Johannes F, Heck Albert J R, Dutcher Susan K, Brown Alan, Zhang Rui, Zeev-Ben-Mordehai Tzviya", "evidence": [ { "database": "UniProtKB", "id": "A0A3Q1MYU9", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1MYU9" } ], "reference": [ { "type": "PubMed", "id": "37327785", "url": "https://glygen.org/publication/PubMed/37327785" } ] }, { "title": "Structural diversity of axonemes across mammalian motile cilia.", "journal": "Nature", "date": "2025", "authors": "Leung Miguel Ricardo, Sun Chen, Zeng Jianwei, Anderson Jacob R, Niu Qingwei, Huang Wei, Noteborn Willem E M, Brown Alan, Zeev-Ben-Mordehai Tzviya, Zhang Rui", "evidence": [ { "database": "UniProtKB", "id": "A0A3Q1MYU9", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1MYU9" } ], "reference": [ { "type": "PubMed", "id": "39743588", "url": "https://glygen.org/publication/PubMed/39743588" } ] } ], "pathway": [], "orthologs": [ { "uniprot_canonical_ac": "A0A8V1AHR8-1", "protein_name": "Sperm acrosome associated 9", "gene_name": "SPACA9", "tax_id": 9031, "organism": "Gallus gallus", "sequence": { "sequence": "MNEVKDTLKVIEDNYKLFLQQQFTFVGALQHTRENAHDMIRPVASISQVQSYMDHHCNNLTDRRILTMFLNICNDLSNLCHKLETLHPGNSTTNEILERCKLLLNHSNDLSTIRAKYPHDVVNHLSCDEAKNHFGGVVSLIPIVLDGVKEWLSHTEKLPRRMLCNVSGGSAVTEKRAPQDAAARAAISPKIPSVHPEAQTSVSNKDCIQVQGNKHVRKKHETDRENQNGKLKGPWKPPGRHAF", "length": 243 }, "evidence": [ { "id": "F6S0F4", "url": "https://omabrowser.org/oma/group/F6S0F4/", "database": "OMA" } ], "glygen_name": "Chicken", "common_name": "Chicken" }, { "uniprot_canonical_ac": "Q7TPM5-1", "protein_name": "Sperm acrosome-associated protein 9", "gene_name": "Spaca9", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MNEVKESLRSIEQKYKLFQQQQFTFIAALEHCRENAHDKIRPISSIEQVQSYMEHYCNNSTHRRILIMFMDICSELSKLCQHFEALHSGTPVTNSLLEKCKTLVSQSNDLSSLRAKYPHEVVNHLSCDEARNHYGGVVSLIPIVLDFMKEWIAHSEKLPRKVLQHGTT", "length": 168 }, "evidence": [ { "id": "F6S0F4", "url": "https://omabrowser.org/oma/group/F6S0F4/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q96E40-1", "protein_name": "Sperm acrosome-associated protein 9", "gene_name": "SPACA9", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MNEVKESLRSIEQKYKLFQQQQLTFTAALEHCRENAHDKIRPISSIGQVQSYMEHYCNSSTDRRVLLMFLDICSELNKLCQHFEAVHSGTPVTNNLLEKCKTLVSQSNDLSSLRAKYPHDVVNHLSCDEARNHYGGVVSLIPLILDLMKEWIAHSEKLPRKVLQHVSEPQAHQESTRGAARPAQAIGTQPRATKHKCRQLTKASLKPRGCSKPPWRPPGGKL", "length": 222 }, "evidence": [ { "id": "F6S0F4", "url": "https://omabrowser.org/oma/group/F6S0F4/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" } ], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 8, "go_terms": [ { "name": "acrosomal vesicle", "id": "GO:0001669", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0001669", "evidence": [ { "database": "UniProtKB", "id": "F6S0F4", "url": "https://www.uniprot.org/uniprotkb/F6S0F4" } ], "pmid": "" }, { "name": "sperm flagellum", "id": "GO:0036126", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0036126", "evidence": [ { "database": "UniProtKB", "id": "F6S0F4", "url": "https://www.uniprot.org/uniprotkb/F6S0F4" } ], "pmid": "" }, { "name": "ciliary base", "id": "GO:0097546", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0097546", "evidence": [ { "database": "UniProtKB", "id": "F6S0F4", "url": "https://www.uniprot.org/uniprotkb/F6S0F4" } ], "pmid": "" }, { "name": "sperm end piece", "id": "GO:0097229", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0097229", "evidence": [ { "database": "UniProtKB", "id": "F6S0F4", "url": "https://www.uniprot.org/uniprotkb/F6S0F4" } ], "pmid": "" }, { "name": "cytosol", "id": "GO:0005829", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005829", "evidence": [ { "database": "UniProtKB", "id": "F6S0F4", "url": "https://www.uniprot.org/uniprotkb/F6S0F4" } ], "pmid": "" }, { "name": "ciliary basal body", "id": "GO:0036064", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0036064", "evidence": [ { "database": "UniProtKB", "id": "F6S0F4", "url": "https://www.uniprot.org/uniprotkb/F6S0F4" } ], "pmid": "" }, { "name": "axonemal microtubule", "id": "GO:0005879", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005879", "evidence": [ { "database": "UniProtKB", "id": "F6S0F4", "url": "https://www.uniprot.org/uniprotkb/F6S0F4" } ], "pmid": "" }, { "name": "axonemal microtubule doublet inner sheath", "id": "GO:0160110", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0160110", "evidence": [ { "database": "UniProtKB", "id": "F6S0F4", "url": "https://www.uniprot.org/uniprotkb/F6S0F4" } ], "pmid": "" } ] }, { "name": "Molecular Function", "total": 2, "go_terms": [ { "name": "microtubule binding", "id": "GO:0008017", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008017", "evidence": [ { "database": "UniProtKB", "id": "F6S0F4", "url": "https://www.uniprot.org/uniprotkb/F6S0F4" } ], "pmid": "" }, { "name": "calcium-dependent protein binding", "id": "GO:0048306", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0048306", "evidence": [ { "database": "UniProtKB", "id": "F6S0F4", "url": "https://www.uniprot.org/uniprotkb/F6S0F4" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 2, "go_terms": [ { "name": "flagellated sperm motility", "id": "GO:0030317", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030317", "evidence": [ { "database": "UniProtKB", "id": "F6S0F4", "url": "https://www.uniprot.org/uniprotkb/F6S0F4" } ], "pmid": "" }, { "name": "axoneme assembly", "id": "GO:0035082", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0035082", "evidence": [ { "database": "UniProtKB", "id": "F6S0F4", "url": "https://www.uniprot.org/uniprotkb/F6S0F4" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 60, "end_pos": 62, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" }, { "name": "homologset.oma", "label": "OMA Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 60, "end_pos": 62 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": 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"InterPro", "categories": [ "Protein Classification" ] }, { "id": "HDGDYQR", "url": "https://omabrowser.org/oma/group/HDGDYQR/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "A0A3Q1N083", "url": "https://www.orthodb.org/?gene=A0A3Q1N083", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "G3N0M7", "url": "https://www.orthodb.org/?gene=G3N0M7", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR46806", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR46806", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR46806:SF1", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR46806:SF1", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00431", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00431", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF00754", "url": 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"https://www.uniprot.org/uniprotkb/A0AAA9TSN9-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0AAA9U1Z5", "url": "https://www.uniprot.org/uniprotkb/A0AAA9U1Z5", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0AAA9U1Z5-1", "url": "https://www.uniprot.org/uniprotkb/A0AAA9U1Z5-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "G3N0M7", "url": "https://www.uniprot.org/uniprotkb/G3N0M7", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "G3N0M7-1", "url": "https://www.uniprot.org/uniprotkb/G3N0M7-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MTSKNYPWTYPNHTVCEKTITVPKGKRLILRLGDLDIESQTCASDYLLFTSSSDQYGPYCGSMTMPKELLLNTNEVTVRFESGSHTSGRGFLLTYASSDHPDLITCLDRANHYLKTEYSKFCPAGCRDVPGDISGNVVDGYRDTSLLCKAAIHAGVIADEVGGQISVFLRKGLSRYEGILANGVLSRDGSLSDKRFLFTSNGCSGSLSLEPDRQIRASSSWEWINETGDQVRWSPGQARLQDQGPSWASGDRSKNHKQREWLRIDLGEKKKITGIRTTGSTQSDFDFYVKSFVMNFRNNNSKWKTYKGIVNNEEKVFQGNSNFRDPVRNNFIPPIVARYVRVIPQTWHQRIALKVELLGCQVAPSRTQGNDSLVWHKTSVNTVGSTKGEDKTISKPIPSEEMPKGLNITTIVILLVLFFVLAAGVAIFAVLRKKKKKGNPYGSSKTQKTDCWKQIKYPFARHQSAEFTISYNNEKEMTQKLDLITSDIADYQQPLMIGTETVTRKGSTFRPMDTEADAAGPGTEAGGHYDCPLPAGRHEYALPLTNPEPEYATPIVERHLARAHTFSARSGYRVPGPRPAHKHSLSSGAFSPAAGYQRPPSPAPAEPGYDQPKGGGLAAGCAPPDHPKPQVSPASSAAYLAPRDCLRPLNPTAMTALL", "length": 658, "header": "tr|G3N0M7-1|G3N0M7_BOVIN Isoform 1 of Discoidin, CUB and LCCL domain containing 1 OS=Bos taurus OX=9913 GN=DCBLD1 PE=4 SV=3 CANONICAL=G3N0M7-1" }, "isoforms": [ { "isoform_ac": "A0A3Q1N083-1", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1N083/entry", "sequence": { "sequence": "MKFKHPSRPSAFGPCSVLWLPTPGHELTCSPRSPHAGPFLPQLFCAAGDGCGHIVTYKDSGTMTSKNYPWTYPNHTVCEKTITVPKGKRLILRLGDLDIESQTCASDYLLFTSSSDQYGPYCGSMTMPKELLLNTNEVTVRFESGSHTSGRGFLLTYASSDHPDLITCLDRANHYLKTEYSKFCPAGCRDVPGDISGNVVDGYRDTSLLCKAAIHAGVIADEVGGQISVFLRKGLSRYEGILANGVLSRDGSLSDKRFLFTSNGCSGSLSLEPDRQIRASSSWEWINETGDQVRWSPGQARLQDQGPSWASGDRSKNHKQREWLRIDLGEKKKITGIRTTGSTQSDFDFYVKSFVMNFRNNNSKWKTYKGIVNNEEKVFQGNSNFRDPVRNNFIPPIVARYVRVIPQTWHQRIALKVELLGCQVAPSRTQGNDSLVWHKTSVNTVGSTKGEDKTISKPIPSEEMPKGLNITTIVILLVLFFVLAAGVAIFAVLRKKKKKGNPYGSSKTQKTDCWKQIKYPFARHQSAEFTISYNNEKEMTQKLDLITSDIADYQQPLMIGTETVTRKGSTFRPMDTEADAAGPGTEAGGHYDCPLPAGRHEYALPLTNPEPEYATPIVERHLARAHTFSARSGYRVPGPRPAHKHSLSSGAFSPAAGYQRPPSPAPAEPGYDQPKGGGLAAGCAPPDHPKPQVSPASSAAYLAPRDCLRPLNPTAMTALL", "length": 720, "header": "tr|A0A3Q1N083-1|G3N0M7_BOVIN Computationally mapped isoform of Discoidin, CUB and LCCL domain containing 1 OS=Bos taurus OX=9913 GN=DCBLD1 PE=4 SV=1 CANONICAL=G3N0M7-1" }, "locus": { "chromosome": "9", "start_pos": 33325413, "end_pos": 33251301, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000069346.2", "url": "https://www.ensembl.org/id/ENSBTAT00000069346.2" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000062028.1", "url": "https://www.ensembl.org/id/ENSBTAP00000062028.1" } ] } }, { "isoform_ac": "A0AAA9SRS5-1", "url": "https://www.uniprot.org/uniprotkb/A0AAA9SRS5/entry", "sequence": { "sequence": "MLSEENGAPGAPPLRRPAATREPLPPWGPACGAGQETPPPGWAPGRPNEIRCPAAAAPSPGAALGREGGGRPGRRRRCARQGEAEPAKLAPGGAMVAGARGGCAQAGAVRRGLLALLLAVFAPLWLQAEELGDGCGHIVTYKDSGTMTSKNYPWTYPNHTVCEKTITVPKGKRLILRLGDLDIESQTCASDYLLFTSSSDQYGPYCGSMTMPKELLLNTNEVTVRFESGSHTSGRGFLLTYASSDHPDLITCLDRANHYLKTEYSKFCPAGCRDVPGDISGNVVDGYRDTSLLCKAAIHAGVIADEVGGQISVFLRKGLSRYEGILANGVLSRDGSLSDKRFLFTSNGCSGSLSLEPDRQIRASSSWEWINETGDQVRWSPGQARLQDQGPSWASGDRSKNHKQREWLRIDLGEKKKITGIRTTGSTQSDFDFYVKSFVMNFRNNNSKWKTYKGIVNNEEKVFQGNSNFRDPVRNNFIPPIVARYVRVIPQTWHQRIALKVELLGCQVAPSRTQGLNITTIVILLVLFFVLAAGVAIFAVLRKKKKKGNPYGSSKTQKTDCWKQIKYPFARHQSAEFTISYNNEKEMTQKLDLITSDIADYQQPLMIGTETVTRKGSTFRPMDTEADAAGPGTEAGGHYDCPLPAGRHEYALPLTNPEPEYATPIVERHLARAHTFSARSGYRVPGPRPAHKHSLSSGAFSPAAGYQRPPSPAPAEPGYDQPKGGGLAAGCAPPDHPKPQVSPASSAAYLAPRDCLRPLNPTAMTALL", "length": 768, "header": "tr|A0AAA9SRS5-1|G3N0M7_BOVIN Computationally mapped isoform of Discoidin, CUB and LCCL domain containing 1 OS=Bos taurus OX=9913 GN=DCBLD1 PE=4 SV=1 CANONICAL=G3N0M7-1" }, "locus": { "chromosome": "9", "start_pos": 33324712, "end_pos": 33251301, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000135144.1", "url": "https://www.ensembl.org/id/ENSBTAT00000135144.1" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000088075.1", "url": "https://www.ensembl.org/id/ENSBTAP00000088075.1" } ] } }, { "isoform_ac": "A0AAA9TSN9-1", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TSN9/entry", "sequence": { "sequence": "MLSEENGAPGAPPLRRPAATREPLPPWGPACGAGQETPPPGWAPGRPNEIRCPAAAAPSPGAALGREGGGRPGRRRRCARQGEAEPAKLAPGGAMVAGARGGCAQAGAVRRGLLALLLAVFAPLWLQAEELGDGCGHIVTYKDSGTMTSKNYPWTYPNHTVCEKTITVPKGKRLILRLGDLDIESQTCASDYLLFTSSSDQYGPYCGSMTMPKELLLNTNEVTVRFESGSHTSGRGFLLTYASSDHPDLITCLDRANHYLKTEYSKFCPAGCRDVPGDISGNVVDGYRDTSLLCKAAIHAGVIADEVGGQISVFLRKGLSRYEGILANGVLSRDGSLSDKRFLFTSNGCSGSLSLEPDRQIRASSSWEWINETGDQVRWSPGQARLQDQGPSWASGDRSKNHKQREWLRIDLGEKKKITGIRTTGSTQSDFDFYVKSFVMNFRNNNSKWKTYKGIVNNEEKVFQGNSNFRDPVRNNFIPPIVARYVRVIPQTWHQRIALKVELLGCQVAPSRTQGNDSLVWHKTSVNTVGSTKGEDKTISKPIPSEEMPKGLNITTIVILLVLFFVLAAGVAIFAVLRKKKKKGNPYGSSKTQKTDCWKQIKYPFARHQSAEFTISYNNEKEMTQKLDLITSDIADYQQPLMIGTETVTRKGSTFRPMDTEADAAGPGTEAGGHYDCPLPAGRHEYALPLTNPEPEYATPIVERHLARAHTFSARSGYRVPGPRPAHKHSLSSGAFSPAAGYQRPPSPAPAEPGYDQPKGGGLAAGCAPPDHPKPQVSPASSAAYLAPRDCLRPLNPTAMTALL", "length": 804, "header": "tr|A0AAA9TSN9-1|G3N0M7_BOVIN Computationally mapped isoform of Discoidin, CUB and LCCL domain containing 1 OS=Bos taurus OX=9913 GN=DCBLD1 PE=4 SV=1 CANONICAL=G3N0M7-1" }, "locus": { "chromosome": "9", "start_pos": 33324712, "end_pos": 33251301, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000116752.1", "url": "https://www.ensembl.org/id/ENSBTAT00000116752.1" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000100067.1", "url": "https://www.ensembl.org/id/ENSBTAP00000100067.1" } ] } }, { "isoform_ac": "A0AAA9U1Z5-1", "url": "https://www.uniprot.org/uniprotkb/A0AAA9U1Z5/entry", "sequence": { "sequence": "MLSEENGAPGAPPLRRPAATREPLPPWGPACGAGQETPPPGWAPGRPNEIRCPAAAAPSPGAALGREGGGRPGRRRRCARQGEAEPAKLAPGGAMVAGARGGCAQAGAVRRGLLALLLAVFAPLWLQAEELGDGCGHIVTYKDSGTMTSKNYPWTYPNHTVCEKTITVPKGKRLILRLGDLDIESQTCASDYLLFTSSSDQYGPYCGSMTMPKELLLNTNEVTVRFESGSHTSGRGFLLTYASSDHPDLITCLDRANHYLKTEYSKFCPAGCRDVPGDISGNVVDGYRDTSLLCKAAIHAGVIADEVGGQISVFLRKGLSRYEGILANGVLSRDGSLSDKRFLFTSNGCSGSLSLEPDRQIRASSSWEWINETGDQVRWSPGQARLQDQGPSWASGDRSKNHKQREWLRIDLGEKKKITGIRTTGSTQSDFDFYVKSFVMNFRNNNSKWKTYKGIVNNEEKVFQGNSNFRDPVRNNFIPPIVARYVRVIPQTWHQRIALKVELLGCQVAPSNDSLVWHKTSVNTVGSTKGEDKTISKPIPSEEMPKGLNITTIVILLVLFFVLAAGVAIFAVLRKKKKKGNPYGSSKTQKTDCWKQIKYPFARHQSAEFTISYNNEKEMTQKLDLITSDIAG", "length": 632, "header": "tr|A0AAA9U1Z5-1|A0AAA9U1Z5_BOVIN Computationally mapped isoform of Discoidin, CUB and LCCL domain containing 1 OS=Bos taurus OX=9913 GN=DCBLD1 PE=4 SV=1 CANONICAL=G3N0M7-1" }, "locus": { "chromosome": "9", "start_pos": 33324712, "end_pos": 33220783, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000094542.1", "url": "https://www.ensembl.org/id/ENSBTAT00000094542.1" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000103352.1", "url": "https://www.ensembl.org/id/ENSBTAP00000103352.1" } ] } }, { "isoform_ac": "G3N0M7-1", "url": "https://www.uniprot.org/uniprotkb/G3N0M7/entry", "sequence": { "sequence": "MTSKNYPWTYPNHTVCEKTITVPKGKRLILRLGDLDIESQTCASDYLLFTSSSDQYGPYCGSMTMPKELLLNTNEVTVRFESGSHTSGRGFLLTYASSDHPDLITCLDRANHYLKTEYSKFCPAGCRDVPGDISGNVVDGYRDTSLLCKAAIHAGVIADEVGGQISVFLRKGLSRYEGILANGVLSRDGSLSDKRFLFTSNGCSGSLSLEPDRQIRASSSWEWINETGDQVRWSPGQARLQDQGPSWASGDRSKNHKQREWLRIDLGEKKKITGIRTTGSTQSDFDFYVKSFVMNFRNNNSKWKTYKGIVNNEEKVFQGNSNFRDPVRNNFIPPIVARYVRVIPQTWHQRIALKVELLGCQVAPSRTQGNDSLVWHKTSVNTVGSTKGEDKTISKPIPSEEMPKGLNITTIVILLVLFFVLAAGVAIFAVLRKKKKKGNPYGSSKTQKTDCWKQIKYPFARHQSAEFTISYNNEKEMTQKLDLITSDIADYQQPLMIGTETVTRKGSTFRPMDTEADAAGPGTEAGGHYDCPLPAGRHEYALPLTNPEPEYATPIVERHLARAHTFSARSGYRVPGPRPAHKHSLSSGAFSPAAGYQRPPSPAPAEPGYDQPKGGGLAAGCAPPDHPKPQVSPASSAAYLAPRDCLRPLNPTAMTALL", "length": 658, "header": "tr|G3N0M7-1|G3N0M7_BOVIN Isoform 1 of Discoidin, CUB and LCCL domain containing 1 OS=Bos taurus OX=9913 GN=DCBLD1 PE=4 SV=3 CANONICAL=G3N0M7-1" }, "locus": { "chromosome": "9", "start_pos": 33298516, "end_pos": 33251301, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000063169.3", "url": "https://www.ensembl.org/id/ENSBTAT00000063169.3" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000055393.3", "url": "https://www.ensembl.org/id/ENSBTAP00000055393.3" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [], "orthologs": [ { "uniprot_canonical_ac": "A0A8V0YFB9-1", "protein_name": "Discoidin, CUB and LCCL domain containing 1", "gene_name": "DCBLD1", "tax_id": 9031, "organism": "Gallus gallus", "sequence": { "sequence": "MGAAALPVLPLPLPTPGPGGRQRCTRRAERGPFASAATPAGRGMPLGGRPPGLAGGPGPGPPLRGREEEKGAGEKRGSCVSPGAGAMSPAGGARAAPSLLFSLLLAASAPLWLRAEKMGDGCGHVVMYQDSGTLASKNYPGTYPNYTLCEKKIQVPQGKRLILKIGDLDIESQKCESSYLTILSSSTLHGPYCGNMMPVPKEIILDSNEATIHFESGSHVSGRGFLLSYASSDHPDLITCLERANHYTKTEYSRYCPAGCRDIAGDISGNIEEGYRDTSLLCKSAIHAGVIADELGGQISVTQQKGISRYEGVVANGISSHDGSLSDKRFMFTSNGCNRSLSLEEGFLSKSQITASSYWEETNEFGQLFQWTPDKAWLQVLGLAWASNHSSSREWLEIDLGEKKRITGIKTTGSGSTLQNFNFYVKTFILNYRNNNSKWRTYRGILSNEEKVFQGNSDSGDIVRNNFIPPIVARYVRIIPQSWNQRIALKLELIGCRIMQVNSSFTHSMWQKTSQSTETSLGKEDRTVTEPIPSEETNLGLKLTAIIVPVLIVLCLFLFSGICICAALRKQEAKGLSYGLSNAQKSGCWKQIKQPFTRHQSTEFTISYNNEKETPQKLDLVTSDMADYQQPLMIGTGTVTRKGSTFRPMDTEEEGRRGSAEFENHYHCPHRANRHEYALPLTSQEPEYATPIIERHVTRENNFPSENGYNVPVISSQKHSLSAGSFSGSCKTDTRNGDYQTPQSVINYDKPKANGILTSVSYSTEYQKPQANALGSEGYSTPRDCLNPISQTAMTALL", "length": 798 }, "evidence": [ { "id": "G3N0M7", "url": "https://omabrowser.org/oma/group/G3N0M7/", "database": "OMA" } ], "glygen_name": "Chicken", "common_name": "Chicken" }, { "uniprot_canonical_ac": "A0ABK0L6J8-1", "protein_name": "Discoidin, CUB and LCCL domain containing 1", "gene_name": "Dcbld1", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MGTGAGGPGVLALLFAVCAPLRLQAEELASEDGVIVVDRHITTICDGCGHIVTSQDSGTMTSKNYPGTYPNYTVCEKIITVPKGKRLILRLGDLNIESKTCASDYLLFSSATDQYGPYCGSWAVPKELWLNSNEVTVRFQSGSHISGRGFLLAYASSDHPDLITCLERGNHYSQEKYSKFCPAGCRDVAGDISGNTKDGYRDTSLLCKAAIHAGIITDELGGQINLLQSKGISHYEGILANGVLSRHGSLSEKRFLFTSPGMSITTVAIPSVIFIALLLTGTGIFAICRKKKKKGNPFVSAEAQKTGCWKQIKYPFARHQSAEFTISYDNEKEMTQKLDLITSDMADYQQPLMIGTGTVTRKGSTFRPMDTDTEEARVNTEASSHYDCPHRPGRHEYALPLTHSEPEYATPIVERHLLRAHTFSTQSGYRVPGPRLTHKHSLSSGGFPPAAGATQIESYQRPASPKPVGGGYDKPAAASSFLDSGDPASQSQMTSGGNDGYSAPRNGLAPLNQMAVTALL", "length": 520 }, "evidence": [ { "id": "G3N0M7", "url": "https://omabrowser.org/oma/group/G3N0M7/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "F1QGI1-1", "protein_name": "Discoidin, CUB and LCCL domain-containing protein 1", "gene_name": "dcbld1", "tax_id": 7955, "organism": "Danio rerio", "sequence": { "sequence": "MSGHTVLYGLILLYSIHPLVLAEKPDDGCGHYVLGQESGVLSSKNYPGTYPNNSWCEWRIRVPIGHTIILKFGDLDMKKRDCESDYLKVLKGSYGSENVYWEYCGDPMPKPSQLHTDSNELTIRFRSSQHITGRGFLLSYSTENHKELLTCLDRGSHFTTAKYRKYCPAGCAALAGEVSGDISLGYRHNSVLCKAAVHAGVIMDQFGGPITVENRRGLSYYPAVRANGIQSKDGSLSETLFTFVTNNCSQQTALQPALITTSLSTHNVSSDGSEVDWLPNSTRISEDLSNKHLLWLQIDLGEKRRITGILTTGLTIAGFEYFVKNFKIEYKERNRWRTFVQYNNSDEMVFEGNTNSLHQTRNTFHPSIISRYIRVVPQQWHRTIAMRLQLLGCSYVKPIPVNASSQVTQEAQPTQPIHNMTKPVASQADFVNLIVIIVPTILLVVLLLVAVCVVKMLHSKKTKENTYDSADTHHTGCWRQIKQPFTRHQSTEFTIKYSSEKDPIQKLDLVTSAMAAEYQQPLMLGTDTVSRKGSTFRPMDTETKDMESSHYDHLQTGIQYALPLTNQEPEYATPIIERHAFRKDPFIPDASYSVPGVVLNKSPSFRAVEGGNCRKVIGGLAGGYQTPQVKPDRGNSPEDIYDSPKIRKAVVLNGPEYQRPQIKSQDQECYSTPRDCVRLPFSGLRPDPEGSRSEPEGSSSDGS", "length": 703 }, "evidence": [ { "id": "G3N0M7", "url": "https://omabrowser.org/oma/group/G3N0M7/", "database": "OMA" } ], "glygen_name": "Zebrafish", "common_name": "Zebrafish" }, { "uniprot_canonical_ac": "Q8N8Z6-1", "protein_name": "Discoidin, CUB and LCCL domain-containing protein 1", "gene_name": "DCBLD1", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MVPGARGGGALARAAGRGLLALLLAVSAPLRLQAEELGDGCGHLVTYQDSGTMTSKNYPGTYPNHTVCEKTITVPKGKRLILRLGDLDIESQTCASDYLLFTSSSDQYGPYCGSMTVPKELLLNTSEVTVRFESGSHISGRGFLLTYASSDHPDLITCLERASHYLKTEYSKFCPAGCRDVAGDISGNMVDGYRDTSLLCKAAIHAGIIADELGGQISVLQRKGISRYEGILANGVLSRDGSLSDKRFLFTSNGCSRSLSFEPDGQIRASSSWQSVNESGDQVHWSPGQARLQDQGPSWASGDSSNNHKPREWLEIDLGEKKKITGIRTTGSTQSNFNFYVKSFVMNFKNNNSKWKTYKGIVNNEEKVFQGNSNFRDPVQNNFIPPIVARYVRVVPQTWHQRIALKVELIGCQITQGNDSLVWRKTSQSTSVSTKKEDETITRPIPSEETSTGINITTVAIPLVLLVVLVFAGMGIFAAFRKKKKKGSPYGSAEAQKTDCWKQIKYPFARHQSAEFTISYDNEKEMTQKLDLITSDMADYQQPLMIGTGTVTRKGSTFRPMDTDAEEAGVSTDAGGHYDCPQRAGRHEYALPLAPPEPEYATPIVERHVLRAHTFSAQSGYRVPGPQPGHKHSLSSGGFSPVAGVGAQDGDYQRPHSAQPADRGYDRPKAVSALATESGHPDSQKPPTHPGTSDSYSAPRDCLTPLNQTAMTALL", "length": 715 }, "evidence": [ { "id": "G3N0M7", "url": "https://omabrowser.org/oma/group/G3N0M7/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "Q9D4J3-1", "protein_name": "Discoidin, CUB and LCCL domain-containing protein 1", "gene_name": "Dcbld1", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MGTGAGGPSVLALLFAVCAPLRLQAEELGDGCGHIVTSQDSGTMTSKNYPGTYPNYTVCEKIITVPKGKRLILRLGDLNIESKTCASDYLLFSSATDQYGPYCGSWAVPKELRLNSNEVTVLFKSGSHISGRGFLLTYASSDHPDLITCLERGSHYFEEKYSKFCPAGCRDIAGDISGNTKDGYRDTSLLCKAAIHAGIITDELGGHINLLQSKGISHYEGLLANGVLSRHGSLSEKRFLFTTPGMNITTVAIPSVIFIALLLTGMGIFAICRKRKKKGNPYVSADAQKTGCWKQIKYPFARHQSTEFTISYDNEKEMTQKLDLITSDMADYQQPLMIGTGTVARKGSTFRPMDTDTEEVRVNTEASGHYDCPHRPGRHEYALPLTHSEPEYATPIVERHLLRAHTFSTQSGYRVPGPRPTHKHSHSSGGFPPATGATQVESYQRPASPKPVGGGYDKPAASSFLDSRDPASQSQMTSGGDDGYSAPRNGLAPLNQTAMTALL", "length": 503 }, "evidence": [ { "id": "G3N0M7", "url": "https://omabrowser.org/oma/group/G3N0M7/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" } ], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 2, "go_terms": [ { "name": "plasma membrane", "id": "GO:0005886", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005886", "evidence": [ { "database": "UniProtKB", "id": "G3N0M7", "url": "https://www.uniprot.org/uniprotkb/G3N0M7" } ], "pmid": "" }, { "name": "membrane", "id": "GO:0016020", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016020", "evidence": [ { "database": "UniProtKB", "id": "G3N0M7", "url": "https://www.uniprot.org/uniprotkb/G3N0M7" } ], "pmid": "" } ] }, { "name": "Molecular Function", "total": 1, "go_terms": [ { "name": "signaling receptor activity", "id": "GO:0038023", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0038023", "evidence": [ { "database": "UniProtKB", "id": "G3N0M7", "url": "https://www.uniprot.org/uniprotkb/G3N0M7" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 12, "end_pos": 14, "annotation": "n_glycosylation_sequon" }, { "start_pos": 225, "end_pos": 227, "annotation": "n_glycosylation_sequon" }, { "start_pos": 299, "end_pos": 301, "annotation": "n_glycosylation_sequon" }, { "start_pos": 370, "end_pos": 372, "annotation": "n_glycosylation_sequon" }, { "start_pos": 407, "end_pos": 409, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "G3N0M7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3N0M7" }, { "id": "PS01180", "database": "PROSITE", "url": "https://prosite.expasy.org/PS01180" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "CUB", "eco_id": "ECO_0000259", "start_pos": 1, "end_pos": 98, "start_aa": "Met", "end_aa": "Ser", "glycosite_overlap": [] }, { "evidence": [ { "id": "G3N0M7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3N0M7" }, { "id": "PS50022", "database": "PROSITE", "url": "https://prosite.expasy.org/PS50022" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "F5/8 type C", "eco_id": "ECO_0000259", "start_pos": 203, "end_pos": 360, "start_aa": "Cys", "end_aa": "Cys", "glycosite_overlap": [] }, { "evidence": [ { "id": "G3N0M7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3N0M7" }, { "id": "PS50820", "database": "PROSITE", "url": "https://prosite.expasy.org/PS50820" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "LCCL", "eco_id": "ECO_0000259", "start_pos": 100, "end_pos": 196, "start_aa": "His", "end_aa": "Phe", "glycosite_overlap": [] } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" }, { "name": "homologset.oma", "label": "OMA Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], 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"database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "IPR003599", "url": "https://www.ebi.ac.uk/interpro/entry/IPR003599", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR007110", "url": "https://www.ebi.ac.uk/interpro/entry/IPR007110", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR013106", "url": "https://www.ebi.ac.uk/interpro/entry/IPR013106", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR013783", "url": "https://www.ebi.ac.uk/interpro/entry/IPR013783", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR036179", "url": "https://www.ebi.ac.uk/interpro/entry/IPR036179", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR042473", "url": "https://www.ebi.ac.uk/interpro/entry/IPR042473", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "QNCTFHT", "url": 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"id": "F6RQ31-1", "url": "https://www.uniprot.org/uniprotkb/F6RQ31-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MEPWRGSALHGRPGVLWGPWSGRPSALTCSTLTRPEVSPPAASRPLSANQEYPLRAPGLRSGPAAPDAALPDGDMGFPPVPEAGSRRWRPVLLAFFLAASRDLVTAFKIATPYSLYVCPEGQNVTLTCRLLGPLAKGHDVTFYKTWYRSSRGEVQVCSERRPIRNLTFQDLHLHHSSHQANTSQDLAQRYGLESASDHHGNFTITMRNLTLLDGGLYCCLVVEIRHHHSEQRLFGAMELQVQRGKETLSKCIAYPPSSNESESITAAALATSACIVGILCLPLILLLVYKQRQVASNRRAQELVRMDSNNIQGIENPGFETSPPSHGMLEAKPRQALSYMAQRQPSESGRHLLSEPNTPLSPPGPGEVFFPSLDPVPDSPNSEAV", "length": 385, "header": "tr|F6RQ31-1|F6RQ31_BOVIN Isoform 1 of V-set immunoregulatory receptor OS=Bos taurus OX=9913 GN=VSIR PE=4 SV=1 CANONICAL=F6RQ31-1" }, "isoforms": [ { "isoform_ac": "A0A3Q1N7U7-1", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1N7U7/entry", "sequence": { "sequence": "MGFPPVPEAGSRRWRPVLLAFFLAASRDLVTAFKIATPYSLYVCPEGQNVTLTCRLLGPLAKGHDVTFYKTWYRSSRGEVQVCSERRPIRNLTFQDLHLHHSSHQANTSQDLAQRYGLESASDHHGNFTITMRNLTLLDGGLYCCLVVEIRHHHSEQRLFGAMELQVQRGKETLSKCIAYPPSSNESESITAAALATSACIVGILCLPLILLLVYKQRQVASNRRAQELVRMDSNNIQGIENPGFETSPPSHGMLEAKPRQALSYMAQRQPSESGRHLLSEPNTPLSPPGPGEVFFPSLAQKECSRLLGRLAWPKPQL", "length": 318, "header": "tr|A0A3Q1N7U7-1|F6RQ31_BOVIN Computationally mapped isoform of V-set immunoregulatory receptor OS=Bos taurus OX=9913 GN=VSIR PE=4 SV=1 CANONICAL=F6RQ31-1" }, "locus": { "chromosome": "28", "start_pos": 27920628, "end_pos": 27894511, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000071127.2", "url": "https://www.ensembl.org/id/ENSBTAT00000071127.2" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000066931.1", "url": "https://www.ensembl.org/id/ENSBTAP00000066931.1" } ] } }, { "isoform_ac": "F6RQ31-1", "url": "https://www.uniprot.org/uniprotkb/F6RQ31/entry", "sequence": { "sequence": "MEPWRGSALHGRPGVLWGPWSGRPSALTCSTLTRPEVSPPAASRPLSANQEYPLRAPGLRSGPAAPDAALPDGDMGFPPVPEAGSRRWRPVLLAFFLAASRDLVTAFKIATPYSLYVCPEGQNVTLTCRLLGPLAKGHDVTFYKTWYRSSRGEVQVCSERRPIRNLTFQDLHLHHSSHQANTSQDLAQRYGLESASDHHGNFTITMRNLTLLDGGLYCCLVVEIRHHHSEQRLFGAMELQVQRGKETLSKCIAYPPSSNESESITAAALATSACIVGILCLPLILLLVYKQRQVASNRRAQELVRMDSNNIQGIENPGFETSPPSHGMLEAKPRQALSYMAQRQPSESGRHLLSEPNTPLSPPGPGEVFFPSLDPVPDSPNSEAV", "length": 385, "header": "tr|F6RQ31-1|F6RQ31_BOVIN Isoform 1 of V-set immunoregulatory receptor OS=Bos taurus OX=9913 GN=VSIR PE=4 SV=1 CANONICAL=F6RQ31-1" }, "locus": { "chromosome": "28", "start_pos": 27920850, "end_pos": 27896387, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000047028.5", "url": "https://www.ensembl.org/id/ENSBTAT00000047028.5" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000044266.4", "url": "https://www.ensembl.org/id/ENSBTAP00000044266.4" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": 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"MGVPAVPEASSPRWGTLLLAIFLAASRGLVAAFKVTTPYSLYVCPEGQNATLTCRILGPVSKGHDVTIYKTWYLSSRGEVQMCKEHRPIRNFTLQHLQHHGSHLKANASHDQPQKHGLELASDHHGNFSITLRNVTPRDSGLYCCLVIELKNHHPEQRFYGSMELQVQAGKGSGSTCMASNEQDSDSITAAALATGACIVGILCLPLILLLVYKQRQVASHRRAQELVRMDSNTQGIENPGFETTPPFQGMPEAKTRPPLSYVAQRQPSESGRYLLSDPSTPLSPPGPGDVFFPSLDPVPDSPNSEAI", "length": 308 }, "evidence": [ { "id": "F6RQ31", "url": "https://omabrowser.org/oma/group/F6RQ31/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q9H7M9-1", "protein_name": "V-type immunoglobulin domain-containing suppressor of T-cell activation", "gene_name": "VSIR", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": 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"https://www.uniprot.org/uniprotkb/F6RQ31" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 12, "go_terms": [ { "name": "regulation of immune response", "id": "GO:0050776", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0050776", "evidence": [ { "database": "UniProtKB", "id": "F6RQ31", "url": "https://www.uniprot.org/uniprotkb/F6RQ31" } ], "pmid": "" }, { "name": "negative regulation of interleukin-10 production", "id": "GO:0032693", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0032693", "evidence": [ { "database": "UniProtKB", "id": "F6RQ31", "url": "https://www.uniprot.org/uniprotkb/F6RQ31" } ], "pmid": "" }, { "name": "negative regulation of interleukin-17 production", "id": "GO:0032700", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0032700", "evidence": [ { "database": "UniProtKB", "id": "F6RQ31", "url": "https://www.uniprot.org/uniprotkb/F6RQ31" } ], "pmid": "" }, { "name": "positive regulation of gene expression", "id": "GO:0010628", "url": 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CD4-positive, alpha-beta T cell proliferation", "id": "GO:2000562", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:2000562", "evidence": [ { "database": "UniProtKB", "id": "F6RQ31", "url": "https://www.uniprot.org/uniprotkb/F6RQ31" } ], "pmid": "" }, { "name": "zymogen activation", "id": "GO:0031638", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0031638", "evidence": [ { "database": "UniProtKB", "id": "F6RQ31", "url": "https://www.uniprot.org/uniprotkb/F6RQ31" } ], "pmid": "" }, { "name": "positive regulation of regulatory T cell differentiation", "id": "GO:0045591", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0045591", "evidence": [ { "database": "UniProtKB", "id": "F6RQ31", "url": "https://www.uniprot.org/uniprotkb/F6RQ31" } ], "pmid": "" }, { "name": "positive regulation of collagen catabolic process", "id": "GO:0120158", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0120158", "evidence": [ { "database": "UniProtKB", "id": "F6RQ31", "url": 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"url": "https://www.ensembl.org/id/ENSBTAP00000003254.5" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [], "orthologs": [], "go_annotation": { "categories": [ { "name": "Biological Process", "total": 4, "go_terms": [ { "name": "lipid metabolic process", "id": "GO:0006629", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006629", "evidence": [ { "database": "UniProtKB", "id": "F6RVE0", "url": "https://www.uniprot.org/uniprotkb/F6RVE0" } ], "pmid": "" }, { "name": "lipid storage", "id": "GO:0019915", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0019915", "evidence": [ { "database": "UniProtKB", "id": "F6RVE0", "url": "https://www.uniprot.org/uniprotkb/F6RVE0" } ], "pmid": "" }, { "name": "lipid droplet organization", "id": "GO:0034389", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0034389", "evidence": [ { "database": "UniProtKB", "id": "F6RVE0", "url": "https://www.uniprot.org/uniprotkb/F6RVE0" } ], "pmid": "" }, { "name": "lipid droplet formation", "id": "GO:0140042", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0140042", "evidence": [ { "database": "UniProtKB", "id": "F6RVE0", "url": "https://www.uniprot.org/uniprotkb/F6RVE0" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 2, "go_terms": [ { "name": "endoplasmic reticulum membrane", "id": "GO:0005789", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005789", "evidence": [ { "database": "UniProtKB", "id": "F6RVE0", "url": "https://www.uniprot.org/uniprotkb/F6RVE0" } ], "pmid": "" }, { "name": "lipid droplet", "id": "GO:0005811", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005811", "evidence": [ { "database": "UniProtKB", "id": "F6RVE0", "url": "https://www.uniprot.org/uniprotkb/F6RVE0" } ], "pmid": "" } ] }, { "name": "Molecular Function", "total": 1, "go_terms": [ { "name": "phospholipid binding", "id": "GO:0005543", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005543", "evidence": [ { "database": "UniProtKB", "id": 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"ENSBTAT00000066030.3", "url": "https://www.ensembl.org/id/ENSBTAT00000066030.3" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000056543.2", "url": "https://www.ensembl.org/id/ENSBTAP00000056543.2" } ] } } ], "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "other", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 165, "start_aa": "Thr", "end_pos": 165, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr165", "evidence": [ { "id": "", "database": "GlyGen", "url": "https://data.glygen.org/" } ], "filter_code": "000000000000000010000.00000000001000.0.01000" }, { "glytoucan_ac": "", "type": "O-linked", "subtype": "other", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", 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"G3N3N6", "url": "https://www.uniprot.org/uniprotkb/G3N3N6" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 6, "go_terms": [ { "name": "DNA-templated transcription", "id": "GO:0006351", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006351", "evidence": [ { "database": "UniProtKB", "id": "G3N3N6", "url": "https://www.uniprot.org/uniprotkb/G3N3N6" } ], "pmid": "" }, { "name": "heart development", "id": "GO:0007507", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007507", "evidence": [ { "database": "UniProtKB", "id": "G3N3N6", "url": "https://www.uniprot.org/uniprotkb/G3N3N6" } ], "pmid": "" }, { "name": "cell differentiation", "id": "GO:0030154", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030154", "evidence": [ { "database": "UniProtKB", "id": "G3N3N6", "url": "https://www.uniprot.org/uniprotkb/G3N3N6" } ], "pmid": "" }, { "name": "positive regulation of transcription by RNA polymerase II", "id": "GO:0045944", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0045944", 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"F6RYL6", "url": "https://www.uniprot.org/uniprotkb/F6RYL6" } ], "common_name": "Bovine", "glygen_name": "Bovine", "reference_species": "Bos taurus [9913]" } ], "gene": [ { "name": "TMCC2", "url": "https://www.uniprot.org/uniprotkb/F6RYL6", "locus": { "chromosome": "16", "start_pos": 3044514, "end_pos": 3031998, "strand": "-", "evidence": [ { "database": "Ensembl Gene", "id": "ENSBTAG00000002361", "url": "https://www.ensembl.org/id/ENSBTAG00000002361" } ] } } ], "crossref": [ { "id": "F6RYL6", "url": "https://alphafold.ebi.ac.uk/entry/F6RYL6", "database": "AlphaFoldDB", "categories": [] }, { "id": "IPR019394", "url": "https://www.ebi.ac.uk/interpro/entry/IPR019394", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "PTHR17613", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR17613", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR17613:SF9", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR17613:SF9", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF10267", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF10267", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "F6RYL6", "url": "https://www.uniprot.org/uniprotkb/F6RYL6", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "F6RYL6-1", "url": "https://www.uniprot.org/uniprotkb/F6RYL6-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MAGAEPGSSGTPARSPVLPRDCDPGGLALPAEGWALRAPGTPSPARLWEAMPTQVDKGDFLALNLAGGPGHGDADGPISLDVPDGAPDPQRTKAAIEHLHQKILKITEQIKIEQEARDDNVAEYLKLANNADKQQASRIKQVFEKKNQKSAQTIAQLHKKLEHYRRRLREIEQNGPSRQPKDVLRDMQQGLKDVGANVRAGISGFGGGVVEGVKGSLSGLSQATHSAVVSKPREFASLIRNKFGSADNIAHLKDPLDDGPPEEAARALSGSATLVSSPKYASDDECSSASASSAGAGSNSGAGPAAAAPGSPKSGQLYGAPGNVDAVLEELREIKEGQSHLEDSMEDLKAQLQRDYTYMTQCLQEERYRYERLEEQLNDLTELHQNEMTNLKQELASMEEKVAYQSYERARDIQEAVESCLTRVTKLELQQQQQQVVQLEGVENANARALLGKFINVILALMAVLLVFVSTVASFITPLMKTRLRVSSTALLALVLLLLWKHWDSLTYLLEHVLLPS", "length": 517, "header": "tr|F6RYL6-1|F6RYL6_BOVIN Isoform 1 of Transmembrane and coiled-coil domain family 2 OS=Bos taurus OX=9913 GN=TMCC2 PE=3 SV=1 CANONICAL=F6RYL6-1" }, "isoforms": [ { "isoform_ac": "F6RYL6-1", "url": "https://www.uniprot.org/uniprotkb/F6RYL6/entry", "sequence": { "sequence": "MAGAEPGSSGTPARSPVLPRDCDPGGLALPAEGWALRAPGTPSPARLWEAMPTQVDKGDFLALNLAGGPGHGDADGPISLDVPDGAPDPQRTKAAIEHLHQKILKITEQIKIEQEARDDNVAEYLKLANNADKQQASRIKQVFEKKNQKSAQTIAQLHKKLEHYRRRLREIEQNGPSRQPKDVLRDMQQGLKDVGANVRAGISGFGGGVVEGVKGSLSGLSQATHSAVVSKPREFASLIRNKFGSADNIAHLKDPLDDGPPEEAARALSGSATLVSSPKYASDDECSSASASSAGAGSNSGAGPAAAAPGSPKSGQLYGAPGNVDAVLEELREIKEGQSHLEDSMEDLKAQLQRDYTYMTQCLQEERYRYERLEEQLNDLTELHQNEMTNLKQELASMEEKVAYQSYERARDIQEAVESCLTRVTKLELQQQQQQVVQLEGVENANARALLGKFINVILALMAVLLVFVSTVASFITPLMKTRLRVSSTALLALVLLLLWKHWDSLTYLLEHVLLPS", "length": 517, "header": "tr|F6RYL6-1|F6RYL6_BOVIN Isoform 1 of Transmembrane and coiled-coil domain family 2 OS=Bos taurus OX=9913 GN=TMCC2 PE=3 SV=1 CANONICAL=F6RYL6-1" }, "locus": { "chromosome": "16", "start_pos": 3043474, "end_pos": 3032951, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000003052.7", "url": "https://www.ensembl.org/id/ENSBTAT00000003052.7" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000003052.6", "url": "https://www.ensembl.org/id/ENSBTAP00000003052.6" } ] } } ], "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "other", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 11, "start_aa": "Thr", "end_pos": 11, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr11", "evidence": [ { "id": "", "database": "GlyGen", "url": "https://data.glygen.org/" } ], "filter_code": "000000000000000010000.00000000001000.0.01000" }, { "glytoucan_ac": "", "type": "O-linked", "subtype": "other", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 41, "start_aa": "Thr", "end_pos": 41, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr41", "evidence": [ { "id": "", "database": "GlyGen", "url": "https://data.glygen.org/" } ], "filter_code": "000000000000000010000.00000000001000.0.01000" } ], "phosphorylation": [], "glycation": [], "keywords": [ "glycoprotein", "glycoprotein_predicted" ], "publication": [], "pathway": [], "orthologs": [], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 2, "go_terms": [ { "name": "endoplasmic reticulum", "id": "GO:0005783", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005783", "evidence": [ { "database": "UniProtKB", "id": "F6RYL6", "url": "https://www.uniprot.org/uniprotkb/F6RYL6" } ], "pmid": "" }, { "name": "membrane", "id": "GO:0016020", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016020", "evidence": [ { "database": "UniProtKB", "id": "F6RYL6", "url": "https://www.uniprot.org/uniprotkb/F6RYL6" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 1, "go_terms": [ { "name": "amyloid precursor protein metabolic process", "id": "GO:0042982", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0042982", "evidence": [ { "database": "UniProtKB", "id": "F6RYL6", "url": "https://www.uniprot.org/uniprotkb/F6RYL6" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [ 11, 41 ], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 2 }, { "field": "total_sites", "count": 2 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 2 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "exact_sites", "count": 2 }, { "field": "exact_o_linked_sites", "count": 2 }, { "field": "fuzzy_sites", "count": 0 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_pos", "start_aa", "end_pos", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 2 }, { "field": "total_sites", "count": 2 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 2 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "exact_sites", "count": 2 }, { "field": "exact_o_linked_sites", "count": 2 }, { "field": "fuzzy_sites", "count": 0 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_pos", "start_aa", "end_pos", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ], "tool_support": { "graph_view": "yes" } }, { "uniprot_canonical_ac": "G3X7L3-1", "uniprot_ac": "G3X7L3", "uniprot_id": "G3X7L3_BOVIN", "mass": { "chemical_mass": 65589.0, "monoisotopic_mass": 65589.0 }, "refseq": { "ac": "XP_015326960", "name": "protein DENND6B isoform X1", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_015326960" }, "gene_names": [ { "name": "DENND6B", "type": "recommended", "evidence": [ { "id": "G3X7L3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3X7L3" } ] }, { "name": "DENND6B", "type": "synonym", "evidence": [ { "id": "XP_015326960", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_015326960" } ] } ], "protein_names": [ { "name": "DENN domain containing 6B", "type": "synonym", "evidence": [ { "id": "G3X7L3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3X7L3/entry#names_and_taxonomy" } ] }, { "name": "protein DENND6B isoform X1", "type": "synonym", "evidence": [ { "id": "XP_015326960", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_015326960" } ] } ], "function": [], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Bos taurus", "taxid": 9913, "evidence": [ { "database": "UniProtKB", "id": "G3X7L3", "url": "https://www.uniprot.org/uniprotkb/G3X7L3" } ], "common_name": "Bovine", "glygen_name": "Bovine", "reference_species": "Bos taurus [9913]" } ], "gene": [ { "name": "DENND6B", "url": "https://www.uniprot.org/uniprotkb/G3X7L3", "locus": { "chromosome": "5", "start_pos": 119668630, "end_pos": 119680303, "strand": "+", "evidence": [ { "database": "Ensembl Gene", "id": "ENSBTAG00000024756", "url": "https://www.ensembl.org/id/ENSBTAG00000024756" } ] } } ], "crossref": [ { "id": "G3X7L3", "url": "https://alphafold.ebi.ac.uk/entry/G3X7L3", "database": "AlphaFoldDB", "categories": [] }, { "id": "ENSBTAG00000024756", "url": "https://bgee.org/?page=gene&gene_id=ENSBTAG00000024756", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "100139352", "url": "https://www.ncbi.nlm.nih.gov/gene/100139352", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR001194", "url": "https://www.ebi.ac.uk/interpro/entry/IPR001194", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR024224", "url": "https://www.ebi.ac.uk/interpro/entry/IPR024224", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR037516", "url": "https://www.ebi.ac.uk/interpro/entry/IPR037516", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "bta:100139352", "url": "https://www.genome.jp/dbget-bin/www_bget?bta:100139352", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "A0A3Q1LH64", "url": "https://www.orthodb.org/?gene=A0A3Q1LH64", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A3Q1M6D4", "url": "https://www.orthodb.org/?gene=A0A3Q1M6D4", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "G3X7L3", "url": "https://www.orthodb.org/?gene=G3X7L3", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR13677", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR13677", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR13677:SF2", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR13677:SF2", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF02141", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF02141", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "R-BTA-8876198", "url": "https://www.reactome.org/PathwayBrowser/#R-BTA-8876198", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "XP_015326960", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_015326960", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A3Q1LH64", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1LH64", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A3Q1LH64-1", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1LH64-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A3Q1M6D4", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1M6D4", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A3Q1M6D4-1", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1M6D4-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "G3X7L3", "url": "https://www.uniprot.org/uniprotkb/G3X7L3", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "G3X7L3-1", "url": "https://www.uniprot.org/uniprotkb/G3X7L3-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MDQGAGAGAGPQRARGRLGAPSSGMRAPGTPWARFSAWLECVCVVTFDLELGQALELVYPSDFQLTDKEKSSICYLSFPDSHSGCLGDTQFSFRIRQCGGQRCPGHAGEKPGDRGAPASLQREPAHYFGYVYFRQVKDSSVKRGYFQKSLVLLSRLPFVRLFQALLGLVAPEFFDKLAPCLEAVCNEIDQWPAPAPGRTLSLPVMGVVLQVHIPSRADTPESGPLEPSGHETLLPAPVVLPSVHELDLFRCFRPVLAHVQLLWELMLLGEPLLVLAPSPAVSSEMVLALTSCLQPLKFCCDYRPYFTIHDSEFKEFTTRTQAPPNVVLGVTNPFFIKTLQHWPHILRVGEPKMSGDLPKQVKLKKPSRLKTLDTKPGLYTAYTAHLHRDKALLRRLLKGLQKKRPSDVQTAVLRRHLLELTQSFIIPLEHYMASLMPLQKGIVPWKTPPQIRPFRQDDFLQSLERSGPQLTCVLKGDWLGLYRRFFKSPHFDGWYRQRHREMTQKLEALHLEAICEANIEIWMKDKSEVEVVDLILKLRERLVRAQGHQLPVKEATLKRARLYIDTAIGSLPKDLQAVLCPP", "length": 582, "header": "tr|G3X7L3-1|G3X7L3_BOVIN Isoform 1 of DENN domain containing 6B OS=Bos taurus OX=9913 GN=DENND6B PE=3 SV=2 CANONICAL=G3X7L3-1" }, "isoforms": [ { "isoform_ac": "A0A3Q1LH64-1", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1LH64/entry", "sequence": { "sequence": "MDQGAGAGAGPQRARGRLGAPSSGMRAPGTPWARFSAWLECVCVVTFDLELGQALEKSSICYLSFPDSHSGCLGDTQFSFRIRQCGGQRCPGHAGEKPGDRGAPASLQREPAHYFGYVYFRQVKDSSVKRGYFQKSLVLLSRLPFVRLFQALLGLVAPEFFDKLAPCLEAVCNEIDQWPAPAPGRTLSLPVMGVVLQVHIPSRADTPESGPLEPSGHETLLPAPVVLPSVHELDLFRCFRPVLAHVQLLWELMLLGEPLLVLAPSPAVSSEMVLALTSCLQPLKFCCDYRPYFTIHDSEFKEFTTRTQAPPNVVLGVTNPFFIKTLQHWPHILRVGEPKMSGDLPKQVKLKKPSRLKTLDTKPGLYTAYTAHLHRDKALLRRLLKGLQKKRPSDVQTAVLRRHLLELTQSFIIPLEHYMASLMPLQKGIVPWKTPPQIRPFRQDDFLQSLERSGPQLTCVLKGDWLGLYRRFFKSPHFDGWYRQRHREMTQKLEALHLEAICEANIEIWMKDKSEVEVVDLILKLRERLVRAQGHQLPVKEATLKRARLYIDTAIGSLPKDLQAVLCPP", "length": 569, "header": "tr|A0A3Q1LH64-1|G3X7L3_BOVIN Computationally mapped isoform of DENN domain containing 6B OS=Bos taurus OX=9913 GN=DENND6B PE=3 SV=1 CANONICAL=G3X7L3-1" }, "locus": { "chromosome": "5", "start_pos": 119680167, "end_pos": 119669634, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000074466.2", "url": "https://www.ensembl.org/id/ENSBTAT00000074466.2" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000058005.1", "url": "https://www.ensembl.org/id/ENSBTAP00000058005.1" } ] } }, { "isoform_ac": "A0A3Q1M6D4-1", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1M6D4/entry", "sequence": { "sequence": "MLQSGSRLEAPGPLPSGGWSEDAQRQGCQHQAPPSEAGTRRLVACTSRRGGKGTAKPLWVGRAGAEASRACPPPSEGASRGRAVGPWRQRGRSEQAAMRLVYPSDFQLTDKEKSSICYLSFPDSHSGCLGDTQFSFRIRQCGGQRCPGHAGEKPGDRGAPASLQREPAHYFGYVYFRQVKDSSVKRGYFQKSLVLLSRLPFVRLFQALLGLVAPEFFDKLAPCLEAVCNEIDQWPAPAPGRTLSLPVMGVVLQVHIPSRADTPESGPLEPSGHETLLPAPVVLPSVHELDLFRCFRPVLAHVQLLWELMLLGEPLLVLAPSPAVSSEMVLALTSCLQPLKFCCDYRPYFTIHDSEFKEFTTRTQAPPNVVLGVTNPFFIKTLQHWPHILRVGEPKMSGDLPKQVKLKKPSRLKTLDTKPGLYTAYTAHLHRDKALLRRLLKGLQKKRPSDVQTAVLRRHLLELTQSFIIPLEHYMASLMPLQKGIVPWKTPPQIRPFRQDDFLQSLERSGPQLTCVLKGDWLGLYRRFFKSPHFDGWYRQRHREMTQKLEALHLEAICEANIEIWMKDKSEVEVVDLILKLRERLVRAQGHQLPVKEATLKRARLYIDTAIGSLPKDLQAVLCPP", "length": 625, "header": "tr|A0A3Q1M6D4-1|G3X7L3_BOVIN Computationally mapped isoform of DENN domain containing 6B OS=Bos taurus OX=9913 GN=DENND6B PE=3 SV=2 CANONICAL=G3X7L3-1" }, "locus": { "chromosome": "5", "start_pos": 119675297, "end_pos": 119669634, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000067401.2", "url": "https://www.ensembl.org/id/ENSBTAT00000067401.2" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000069287.2", "url": "https://www.ensembl.org/id/ENSBTAP00000069287.2" } ] } }, { "isoform_ac": "G3X7L3-1", "url": "https://www.uniprot.org/uniprotkb/G3X7L3/entry", "sequence": { "sequence": "MDQGAGAGAGPQRARGRLGAPSSGMRAPGTPWARFSAWLECVCVVTFDLELGQALELVYPSDFQLTDKEKSSICYLSFPDSHSGCLGDTQFSFRIRQCGGQRCPGHAGEKPGDRGAPASLQREPAHYFGYVYFRQVKDSSVKRGYFQKSLVLLSRLPFVRLFQALLGLVAPEFFDKLAPCLEAVCNEIDQWPAPAPGRTLSLPVMGVVLQVHIPSRADTPESGPLEPSGHETLLPAPVVLPSVHELDLFRCFRPVLAHVQLLWELMLLGEPLLVLAPSPAVSSEMVLALTSCLQPLKFCCDYRPYFTIHDSEFKEFTTRTQAPPNVVLGVTNPFFIKTLQHWPHILRVGEPKMSGDLPKQVKLKKPSRLKTLDTKPGLYTAYTAHLHRDKALLRRLLKGLQKKRPSDVQTAVLRRHLLELTQSFIIPLEHYMASLMPLQKGIVPWKTPPQIRPFRQDDFLQSLERSGPQLTCVLKGDWLGLYRRFFKSPHFDGWYRQRHREMTQKLEALHLEAICEANIEIWMKDKSEVEVVDLILKLRERLVRAQGHQLPVKEATLKRARLYIDTAIGSLPKDLQAVLCPP", "length": 582, "header": "tr|G3X7L3-1|G3X7L3_BOVIN Isoform 1 of DENN domain containing 6B OS=Bos taurus OX=9913 GN=DENND6B PE=3 SV=2 CANONICAL=G3X7L3-1" }, "locus": { "chromosome": "5", "start_pos": 119680167, "end_pos": 119669634, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000034474.6", "url": "https://www.ensembl.org/id/ENSBTAT00000034474.6" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000034366.5", "url": "https://www.ensembl.org/id/ENSBTAP00000034366.5" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [ { "id": "bta:100139352", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?bta:100139352", "resource": "KEGG Pathway" }, { "id": "R-BTA-8876198", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-BTA-8876198", "resource": "Reactome", "description": "RAB GEFs exchange GTP for GDP on RABs" } ], "orthologs": [], "go_annotation": { "categories": [ { "name": "Molecular Function", "total": 1, "go_terms": [ { "name": "guanyl-nucleotide exchange factor activity", "id": "GO:0005085", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005085", "evidence": [ { "database": "UniProtKB", "id": "G3X7L3", "url": "https://www.uniprot.org/uniprotkb/G3X7L3" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 1, "go_terms": [ { "name": "recycling endosome", "id": "GO:0055037", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0055037", "evidence": [ { "database": "UniProtKB", "id": "G3X7L3", "url": "https://www.uniprot.org/uniprotkb/G3X7L3" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "G3X7L3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3X7L3" }, { "id": "PS50211", "database": "PROSITE", "url": "https://prosite.expasy.org/PS50211" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "UDENN", "eco_id": "ECO_0000259", "start_pos": 40, "end_pos": 496, "start_aa": "Glu", "end_aa": "Arg", "glycosite_overlap": [] } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ], "tool_support": { "graph_view": "yes" } }, { "uniprot_canonical_ac": "G3MZW1-1", "uniprot_ac": "G3MZW1", "uniprot_id": "G3MZW1_BOVIN", "mass": { "chemical_mass": 220448.0, "monoisotopic_mass": 220448.0 }, "refseq": {}, "gene_names": [ { "name": "BRD10", "type": "recommended", "evidence": [ { "id": "G3MZW1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3MZW1" } ] }, { "name": "KIAA2026", "type": "synonym", "evidence": [ { "id": "G3MZW1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3MZW1" } ] } ], "protein_names": [ { "name": "Bromodomain containing 10", "type": "synonym", "evidence": [ { "id": "G3MZW1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3MZW1/entry#names_and_taxonomy" } ] } ], "function": [], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Bos taurus", "taxid": 9913, "evidence": [ { "database": "UniProtKB", "id": "G3MZW1", "url": "https://www.uniprot.org/uniprotkb/G3MZW1" } ], "common_name": "Bovine", "glygen_name": "Bovine", "reference_species": "Bos taurus [9913]" } ], "gene": [ { "name": "BRD10", "url": "https://www.uniprot.org/uniprotkb/G3MZW1", "locus": { "chromosome": "8", "start_pos": 38792352, "end_pos": 38683246, "strand": "-", "evidence": [ { "database": "Ensembl Gene", "id": "ENSBTAG00000047550", "url": "https://www.ensembl.org/id/ENSBTAG00000047550" } ] } } ], "crossref": [ { "id": "ENSBTAG00000047550", "url": "https://bgee.org/?page=gene&gene_id=ENSBTAG00000047550", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "cd04369", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd04369", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "616937", "url": "https://www.ncbi.nlm.nih.gov/gene/616937", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR036427", "url": "https://www.ebi.ac.uk/interpro/entry/IPR036427", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR040214", "url": "https://www.ebi.ac.uk/interpro/entry/IPR040214", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR056522", "url": "https://www.ebi.ac.uk/interpro/entry/IPR056522", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "bta:616937", "url": "https://www.genome.jp/dbget-bin/www_bget?bta:616937", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "DAQENAY", "url": "https://omabrowser.org/oma/group/DAQENAY/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "A0A3Q1LPU9", "url": "https://www.orthodb.org/?gene=A0A3Q1LPU9", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A3Q1MR27", "url": "https://www.orthodb.org/?gene=A0A3Q1MR27", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "G3MZW1", "url": "https://www.orthodb.org/?gene=G3MZW1", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR31095", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR31095", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR31095:SF3", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR31095:SF3", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF23450", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF23450", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "A0A3Q1LPU9", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1LPU9", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A3Q1LPU9-1", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1LPU9-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A3Q1MR27", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1MR27", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A3Q1MR27-1", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1MR27-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "G3MZW1", "url": "https://www.uniprot.org/uniprotkb/G3MZW1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "G3MZW1-1", "url": "https://www.uniprot.org/uniprotkb/G3MZW1-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MSVPGKPGEMKPAGEEERPPPAAEEEDDDELVAAAPALRPARRSASLREDADDDEEEEEMVVGGGGCKEQELTYELQQGYRILGEFLQEKHRGLTAPFLQPLGGVATREEEAAEGPRGGGRGSRALPQQPGQGMCLLKMEEKFASGQYGGITEFVADFRLMLETCYRQHGVDHWISKQGQKLEMMLEQKLALLSRLREQERKEAEEASQKEIEEWERKLLAQAAPTCMETMWEIPAIGHFLCLAQQILNLPEIVFYELERCLLMPQCNAFLSKIMTSLLSPPHRRPTLHRRPTLPYRTWEAALRQKVQQWYTAVGQTENPDNCAEKLGLCPQFFKVLGEVNPLEEKPFHELPFYQKVWILKGLCDFVYETQKEVQDAVLGQPIHECREVILGYDYLENAYVHFPQFCGADVRIYKQRPFQAPEFPIPPIKIQRVPRIKLEKLKCDYVSASNGEHRCSREGLPSAFRKEQEINFDPTCCPAKMNLDNHDISVETEVNSNCEIRIRRPCEMNITDCCKENLEKPGSPGEVTSFGEPLSPGEIRFIENQEKYGEASRVKPEPSPLKENALKSCQIHVNGSHSDHPDINCHKVVRDILLEQSLQSHKKLKLTKMRAKKKKKKKKKLKDILNENLQRKRESLHSLAFKSYKPEIQNKLLIIKKKAKHKKHKSGKKSISKKAITKKRKTVTKSPTVPEFQLICTNLDELRELITKIENELKDLENNRKKSGKWYHRRQAVKELHSTLIRLLNELLPWEPKLMKAFQRNRSRLKKDYDDFRRQPDHDKFARELWTSEEGEGDPGRETPKVEISSKSVDTTEPLDILEKDHFDLDDMKLSEIDFPMARSKLLKKELPSKDVLKTLPKTLKRQSKQISYLDDSTKELSPRKKAKLSTNETVVENAEGDVQMDCLNESKHTEPLCPESFASLDSTPVSTLQKGTKPIQALLAKNIGNKVTLTNQLPPSTGRSAPAVEKPVISPPEASPIKPALTCHTSTKGPLQMVYKMPCGQWLPLDLHNSSVKIQMQPMLDPKSGEKIMQQVLILPKNFVIQHKEGKAVAKEIPPLQQKGTEQHGSSFPQTANVNSSLPSVLVNPTGTVSTQLPNTAFNKTVTPLSNVSSARPQSLTSVTSISNLLAPPVKTSQSEAGKFKNTVSATAFPQPIASPTISSTVQPQLSATTLNGSTNSSSSLNCFAQQTADSSEAKQELKTVCIRDSQSILVRTRGGNTGVVKVQTNPDQNSPNSLSSSSVFTIAPQLQAFLVPKSTASSSSAFSSVAGTTATSSLPSFGQALTSVSIPAGFNPSTGKNLKFTLSQPSCSGNLGHMIDKTSPMPSSPLKSSVSSSPLLSTANSSVSVINVSTGNCGQTSSNVIRTPAKHQQVDYVTKSYPVTRSEATANGDTISGTPVQKLMLVSAPSVLSSGSGTSINVAPAPTSPGVSAQKLVFINAAIPSGTSTPTIVAEPLKQALPSPLSKTYVKPPEQPQIVLIPSTVGTPIKINSSPTVSQIKDVKIGLNIGQAIVNTSGSVPALPSINILQNVTSKGEEKSSKGYVLPLSTSGSSIPVSSNFMSQNITPVNESVVSASRTVNMFSGTGANVSLGSVSVTSTPASVGTRPPVLVSGNDTSSRIMPSLSNRLCTSNLGNTVAISTVKTGHLASSVLISATQPTVSPKCLTSALQIPVTVALPTPVTISPKIINTVAQAATVPGTTRSVSLSKRQSRTSVQFQSPGVSTTVPTNINTNKPQTELPSLSPNPGKIINISNFASLPNQQMSPAFLKSIPSYSSTPGVTAIHTATAPSNVTSLIGSQFSEPCIQQKIVINTSTPLAPGTQIMINGARFIVPPQGLGAGSHVLLISTNPKYGPPLVVNSGQGAQPTPVDNLAQKITLASNNSLSGQPVKHCLKSSTKIVNSLGNASSLSTIPAAPQIINPTAKVSVPPPVPTVSLTSVIKSPPATLLAKTSLVSAICSSNPPLPSNTSVFHLDTSVKKLLVSPEGAILNTINTPASKVSSVSPSLSQIVSASRNPASVFPAFQSSGLEKPDTAAS", "length": 2036, "header": "tr|G3MZW1-1|G3MZW1_BOVIN Isoform 1 of Bromodomain containing 10 OS=Bos taurus OX=9913 GN=BRD10 PE=4 SV=2 CANONICAL=G3MZW1-1" }, "isoforms": [ { "isoform_ac": "A0A3Q1LPU9-1", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1LPU9/entry", "sequence": { "sequence": "MSVPGKPGEMKPAGEEERPPPAAEEEDDDELVAAAPALRPARRSASLREDADDDEEEEEMVVGGGGCKEQELTYELQQGYRILGEFLQEKHRGLTAPFLQPLGGVATREEEAAEGPRGGGRGSRALPQQPGQGMCLLKMEEKFASGQYGGITEFVADFRLMLETCYRQHGVDHWISKQGQKLEMMLEQKLALLSRHLREKTTIAVTSRGYYGLEDEKGTACTSTRRRSTPRSLAGLTSGVFESVMVQVLRQEEQLRAKEEKRLREQERKEAEEASQKEIEEWERKLLAQAAPTCMETMWEIPAIGHFLCLAQQILNLPEIVFYELERCLLMPQCNAFLSKIMTSLLSPPHRRPTLHRRPTLPYRTWEAALRQKVQQWYTAVGQTENPDNCAEKLGLCPQFFKVLGEVNPLEEKPFHELPFYQKVWILKGLCDFVYETQKEVQDAVLGQPIHECREVILGYDYLENAYVHFPQFCGADVRIYKQRPFQAPEFPIPPIKIQRVPRIKLEKLKCDYVSASNGEHRCSREGLPSAFRKEQEINFDPTCCPAKMNLDNHDISVETEVNSNCEIRIRRPCEMNITDCCKENLEKPGSPGEVTSFGEPLSPGEIRFIENQEKYGEASRVKPEPSPLKENALKSCQIHVNGSHSDHPDINCHKVVRDILLEQSLQSHKKLKLTKMRAKKKKKKKKKLKDILNENLQRKRESLHSLAFKSYKPEIQNKLLIIKKKAKHKKHKSGKKSISKKAITKKRKTVTKSPTVPEFQGKWYHRRQAVKELHSTLIRLLNELLPWEPKLMKAFQRNRSRLKKDYDDFRRQPDHDKFARELWTSEEGEGDPGRETPKVEISSKSVDTTEPLDILEKDHFDLDDMKLSEIDFPMARSKLLKKELPSKDVLKTLPKTLKRQSKQISYLDDSTKELSPRKKAKLSTNETVVENAEGDVQMDCLNESKHTEPLCPESFASLDSTPVSTLQKGTKPIQALLAKNIGNKVTLTNQLPPSTGRSAPAVEKPVISPPEASPIKPALTCHTSTKGPLQMVYKMPCGQWLPLDLHNSSVKIQMQPMLDPKSGEKIMQQVLILPKNFVIQHKEGKAVAKEIPPLQQKGTEQHGSSFPQTANVNSSLPSVLVNPTGTVSTQLPNTAFNKTVTPLSNVSSARPQSLTSVTSISNLLAPPVKTSQSEAGKFKNTVSATAFPQPIASPTISSTVQPQLSATTLNGSTNSSSSLNCFAQQTADSSEAKQELKTVCIRDSQSILVRTRGGNTGVVKVQTNPDQNSPNSLSSSSVFTIAPQLQAFLVPKSTASSSSAFSSVAGTTATSSLPSFGQALTSVSIPAGFNPSTGKNLKFTLSQPSCSGNLGHMIDKTSPMPSSPLKSSVSSSPLLSTANSSVSVINVSTGNCGQTSSNVIRTPAKHQQVDYVTKSYPVTRSEATANGDTISGTPVQKLMLVSAPSVLSSGSGTSINVAPAPTSPGVSAQKLVFINAAIPSGTSTPTIVAEPLKQALPSPLSKTYVKPPEQPQIVLIPSTVGTPIKINSSPTVSQIKDVKIGLNIGQAIVNTSGSVPALPSINILQNVTSKGEEKSSKGYVLPLSTSGSSIPVSSNFMSQNITPVNESVVSASRTVNMFSGTGANVSLGSVSVTSTPASVGTRPPVLVSGNDTSSRIMPSLSNRLCTSNLGNTVAISTVKTGHLASSVLISATQPTVSPKCLTSALQIPVTVALPTPVTISPKIINTVAQAATVPGTTRSVSLSKRQSRTSVQFQSPGVSTTVPTNINTNKPQTELPSLSPNPGKIINISNFASLPNQQMSPAFLKSIPSYSSTPGVTAIHTATAPSNVTSLIGSQFSEPCIQQKIVINTSTPLAPGTQIMINGARFIVPPQGLGAGSHVLLISTNPKYGPPLVVNSGQGAQPTPVDNLAQKITLASNNSLSGQPVKHCLKSSTKIVNSLGNASSLSTIPAAPQIINPTAKVSVPPPVPTVSLTSVIKSPPATLLAKTSLVSAICSSNPPLPSNTSVFHLDTSVKKLLVSPEGAILNTINTPASKVSSVSPSLSQIVSASRNPASVFPAFQSSGLEKPDTAAS", "length": 2073, "header": "tr|A0A3Q1LPU9-1|G3MZW1_BOVIN Computationally mapped isoform of Bromodomain containing 10 OS=Bos taurus OX=9913 GN=BRD10 PE=4 SV=1 CANONICAL=G3MZW1-1" }, "locus": { "chromosome": "8", "start_pos": 38791348, "end_pos": 38683445, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000067321.3", "url": "https://www.ensembl.org/id/ENSBTAT00000067321.3" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000059033.1", "url": "https://www.ensembl.org/id/ENSBTAP00000059033.1" } ] } }, { "isoform_ac": "A0A3Q1MR27-1", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1MR27/entry", "sequence": { "sequence": "MSVPGKPGEMKPAGEEERPPPAAEEEDDDELVAAAPALRPARRSASLREDADDDEEEEEMVVGGGGCKEQELTYELQQGYRILGEFLQEKHRGLTAPFLQPLGGVATREEEAAEGPRGGGRGSRALPQQPGQGMCLLKMEEKFASGQYGGITEFVADFRLMLETCYRQHGVDHWISKQGQKLEMMLEQKLALLSRHLREKTTIAVTSRGYYGLEDEKGTACTSTRRRSTPRSLAGLTSGVFESVMVQVLRQEEQLRAKEEKRLREQERKEAEEASQKEIEEWERKLLAQAAPTCMETMWEIPAIGHFLCLAQQILNLPEIVFYELERCLLMPQCNAFLSKIMTSLLSPPHRRPTLHRRPTLPYRTWEAALRQKVQQWYTAVGQTENPDNCAEKLGLCPQFFKVLGEVNPLEEKPFHELPFYQKVWILKGLCDFVYETQKEVQDAVLGQPIHECREVILGYDYLENAYVHFPQFCGADVRIYKQRPFQAPEFPIPPIKIQRVPRIKLEKLKCDYVSASNGEHRCSREGLPSAFRKEQEINFDPTCCPAKMNLDNHDISVETEVNSNCEIRIRRPCEMNITDCCKENLEKPGSPGEVTSFGEPLSPGEIRFIENQEKYGEASRVKPEPSPLKENALKSCQIHVNGSHSDHPDINCHKVVRDILLEQSLQSHKKLKLTKMRAKKKKKKKKKLKDILNENLQRKRESLHSLAFKSYKPEIQNKLLIIKKKAKHKKHKSGKKSISKKAITKKRKTVTKSPTVPEFQLICTNLDELRELITKIENELKDLENNRKKSGKWYHRRQAVKELHSTLIRLLNELLPWEPKLMKAFQRNRSRLKKDYDDFRRQPDHDKFARELWTSEEGEGDPGRETPKVEISSKSVDTTEPLDILEKDHFDLDDMKLSEIDFPMARSKLLKKELPSKDVLKTLPKTLKRQSKQISYLDDSTKELSPRKKAKLSTNETVVENAEGDVQMDCLNESKHTEPLCPESFASLDSTPVSTLQKGTKPIQALLAKNIGNKVTLTNQLPPSTGRSAPAVEKPVISPPEASPIKPALTCHTSTKGPLQMVYKMPCGQWLPLDLHNSSVKIQMQPMLDPKSGEKIMQQVLILPKNFVIQHKEGKAVAKEIPPLQQKGTEQHGSSFPQTANVNSSLPSVLVNPTGTVSTQLPNTAFNKTVTPLSNVSSARPQSLTSVTSISNLLAPPVKTSQSEAGKFKNTVSATAFPQPIASPTISSTVQPQLSATTLNGSTNSSSSLNCFAQQTADSSEAKQELKTVCIRDSQSILVRTRGGNTGVVKVQTNPDQNSPNSLSSSSVFTIAPQLQAFLVPKSTASSSSAFSSVAGTTATSSLPSFGQALTSVSIPAGFNPSTGKNLKFTLSQPSCSGNLGHMIDKTSPMPSSPLKSSVSSSPLLSTANSSVSVINVSTGNCGQTSSNVIRTPAKHQQVDYVTKSYPVTRSEATANGDTISGTPVQKLMLVSAPSVLSSGSGTSINVAPAPTSPGVSAQKLVFINAAIPSGTSTPTIVAEPLKQALPSPLSKTYVKPPEQPQIVLIPSTVGTPIKINSSPTVSQIKDVKIGLNIGQAIVNTSGSVPALPSINILQNVTSKGEEKSSKGYVLPLSTSGSSIPVSSNFMSQNITPVNESVVSASRTVNMFSGTGANVSLGSVSVTSTPASVGTRPPVLVSGNDTSSRIMPSLSNRLCTSNLGNTVAISTVKTGHLASSVLISATQPTVSPKCLTSALQIPVTVALPTPVTISPKIINTVAQAATVPGTTRSVSLSKRQSRTSVQFQSPGVSTTVPTNINTNKPQTELPSLSPNPGKIINISNFASLPNQQMSPAFLKSIPSYSSTPGVTAIHTATAPSNVTSLIGSQFSEPCIQQKIVINTSTPLAPGTQIMINGARFIVPPQGLGAGSHVLLISTNPKYGPPLVVNSGQGAQPTPVDNLAQKITLASNNSLSGQPVKHCLKSSTKIVNSLGNASSLSTIPAAPQIINPTAKVSVPPPVPTVSLTSVIKSPPATLLAKTSLVSAICSSNPPLPSNTSVFHLDTSVKKLLVSPEGAILNTINTPASKVSSVSPSLSQIVSASRNPASVFPAFQSSGLEKPDTAAS", "length": 2103, "header": "tr|A0A3Q1MR27-1|G3MZW1_BOVIN Computationally mapped isoform of Bromodomain containing 10 OS=Bos taurus OX=9913 GN=BRD10 PE=4 SV=1 CANONICAL=G3MZW1-1" }, "locus": { "chromosome": "8", "start_pos": 38791348, "end_pos": 38683445, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000083215.3", "url": "https://www.ensembl.org/id/ENSBTAT00000083215.3" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000072229.1", "url": "https://www.ensembl.org/id/ENSBTAP00000072229.1" } ] } }, { "isoform_ac": "G3MZW1-1", "url": "https://www.uniprot.org/uniprotkb/G3MZW1/entry", "sequence": { "sequence": "MSVPGKPGEMKPAGEEERPPPAAEEEDDDELVAAAPALRPARRSASLREDADDDEEEEEMVVGGGGCKEQELTYELQQGYRILGEFLQEKHRGLTAPFLQPLGGVATREEEAAEGPRGGGRGSRALPQQPGQGMCLLKMEEKFASGQYGGITEFVADFRLMLETCYRQHGVDHWISKQGQKLEMMLEQKLALLSRLREQERKEAEEASQKEIEEWERKLLAQAAPTCMETMWEIPAIGHFLCLAQQILNLPEIVFYELERCLLMPQCNAFLSKIMTSLLSPPHRRPTLHRRPTLPYRTWEAALRQKVQQWYTAVGQTENPDNCAEKLGLCPQFFKVLGEVNPLEEKPFHELPFYQKVWILKGLCDFVYETQKEVQDAVLGQPIHECREVILGYDYLENAYVHFPQFCGADVRIYKQRPFQAPEFPIPPIKIQRVPRIKLEKLKCDYVSASNGEHRCSREGLPSAFRKEQEINFDPTCCPAKMNLDNHDISVETEVNSNCEIRIRRPCEMNITDCCKENLEKPGSPGEVTSFGEPLSPGEIRFIENQEKYGEASRVKPEPSPLKENALKSCQIHVNGSHSDHPDINCHKVVRDILLEQSLQSHKKLKLTKMRAKKKKKKKKKLKDILNENLQRKRESLHSLAFKSYKPEIQNKLLIIKKKAKHKKHKSGKKSISKKAITKKRKTVTKSPTVPEFQLICTNLDELRELITKIENELKDLENNRKKSGKWYHRRQAVKELHSTLIRLLNELLPWEPKLMKAFQRNRSRLKKDYDDFRRQPDHDKFARELWTSEEGEGDPGRETPKVEISSKSVDTTEPLDILEKDHFDLDDMKLSEIDFPMARSKLLKKELPSKDVLKTLPKTLKRQSKQISYLDDSTKELSPRKKAKLSTNETVVENAEGDVQMDCLNESKHTEPLCPESFASLDSTPVSTLQKGTKPIQALLAKNIGNKVTLTNQLPPSTGRSAPAVEKPVISPPEASPIKPALTCHTSTKGPLQMVYKMPCGQWLPLDLHNSSVKIQMQPMLDPKSGEKIMQQVLILPKNFVIQHKEGKAVAKEIPPLQQKGTEQHGSSFPQTANVNSSLPSVLVNPTGTVSTQLPNTAFNKTVTPLSNVSSARPQSLTSVTSISNLLAPPVKTSQSEAGKFKNTVSATAFPQPIASPTISSTVQPQLSATTLNGSTNSSSSLNCFAQQTADSSEAKQELKTVCIRDSQSILVRTRGGNTGVVKVQTNPDQNSPNSLSSSSVFTIAPQLQAFLVPKSTASSSSAFSSVAGTTATSSLPSFGQALTSVSIPAGFNPSTGKNLKFTLSQPSCSGNLGHMIDKTSPMPSSPLKSSVSSSPLLSTANSSVSVINVSTGNCGQTSSNVIRTPAKHQQVDYVTKSYPVTRSEATANGDTISGTPVQKLMLVSAPSVLSSGSGTSINVAPAPTSPGVSAQKLVFINAAIPSGTSTPTIVAEPLKQALPSPLSKTYVKPPEQPQIVLIPSTVGTPIKINSSPTVSQIKDVKIGLNIGQAIVNTSGSVPALPSINILQNVTSKGEEKSSKGYVLPLSTSGSSIPVSSNFMSQNITPVNESVVSASRTVNMFSGTGANVSLGSVSVTSTPASVGTRPPVLVSGNDTSSRIMPSLSNRLCTSNLGNTVAISTVKTGHLASSVLISATQPTVSPKCLTSALQIPVTVALPTPVTISPKIINTVAQAATVPGTTRSVSLSKRQSRTSVQFQSPGVSTTVPTNINTNKPQTELPSLSPNPGKIINISNFASLPNQQMSPAFLKSIPSYSSTPGVTAIHTATAPSNVTSLIGSQFSEPCIQQKIVINTSTPLAPGTQIMINGARFIVPPQGLGAGSHVLLISTNPKYGPPLVVNSGQGAQPTPVDNLAQKITLASNNSLSGQPVKHCLKSSTKIVNSLGNASSLSTIPAAPQIINPTAKVSVPPPVPTVSLTSVIKSPPATLLAKTSLVSAICSSNPPLPSNTSVFHLDTSVKKLLVSPEGAILNTINTPASKVSSVSPSLSQIVSASRNPASVFPAFQSSGLEKPDTAAS", "length": 2036, "header": "tr|G3MZW1-1|G3MZW1_BOVIN Isoform 1 of Bromodomain containing 10 OS=Bos taurus OX=9913 GN=BRD10 PE=4 SV=2 CANONICAL=G3MZW1-1" }, "locus": { "chromosome": "8", "start_pos": 38791348, "end_pos": 38683445, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000063356.4", "url": "https://www.ensembl.org/id/ENSBTAT00000063356.4" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000055115.2", "url": "https://www.ensembl.org/id/ENSBTAP00000055115.2" } ] } } ], "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "other", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 1426, "start_aa": "Thr", "end_pos": 1426, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr1426", "evidence": [ { "id": "", "database": "GlyGen", "url": "https://data.glygen.org/" } ], "filter_code": "000000000000000010000.00000000001000.0.01000" }, { "glytoucan_ac": "", "type": "O-linked", "subtype": "other", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 1777, "start_aa": "Thr", "end_pos": 1777, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr1777", "evidence": [ { "id": "", "database": "GlyGen", "url": "https://data.glygen.org/" } ], "filter_code": "000000000000000010000.00000000001000.0.01000" }, { "glytoucan_ac": "", "type": "O-linked", "subtype": "other", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 1867, "start_aa": "Thr", "end_pos": 1867, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr1867", "evidence": [ { "id": "", "database": "GlyGen", "url": "https://data.glygen.org/" } ], "filter_code": "000000000000000010000.00000000001000.0.01000" }, { "glytoucan_ac": "", "type": "O-linked", "subtype": "other", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 1933, "start_aa": "Thr", "end_pos": 1933, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr1933", "evidence": [ { "id": "", "database": "GlyGen", "url": "https://data.glygen.org/" } ], "filter_code": "000000000000000010000.00000000001000.0.01000" } ], "phosphorylation": [], "glycation": [], "keywords": [ "glycoprotein", "glycoprotein_predicted" ], "publication": [], "pathway": [ { "id": "bta:616937", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?bta:616937", "resource": "KEGG Pathway" } ], "orthologs": [ { "uniprot_canonical_ac": "A0A8V0YJQ7-1", "protein_name": "Bromodomain containing 10", "gene_name": "KIAA2026", "tax_id": 9031, "organism": "Gallus gallus", "sequence": { "sequence": "MLRSRPAAGGAPAAAEALCARGAADMDSARPADVAEQTAGHAAGGDLSVERASACPPQRREEQRDEDGSDAGGESGGCSWEQSLSPELQQGYRILREFLLEKYRPLTAPFLKPLADQECVRAEGGAGSLSGHNSSHSAQQSPAGMWLLKMEEKFSSGQYAGIADFVGDFRQMLETCYRLHGVDHWLSKQAQKLEMMLEQKLALLSRHLREKTSLAVTSRGSYGLEDEKGTPCTSTRRRSTPRNLVGLSTGMFESVMVQVLRQEEQLRAKEEKRMREQERKEAEEASQKEIEEWEKSLLAQAAPTRMETMWEIPAIGHFLCLAQQILNLPEIVFYELERCLLMPQCNAFLSKIMTSLLSPPHRRSTLHRRPTLSYRAWEAALRQKVQHWYNVVGQTDNPNSSAEKLGLCPQFFKVLGEVNPLQEKPFHELPFYQKVWLLKGLCDFVYETQKDVQDAVLGQPIHECREVILGYDYLENAYVHFPQFCGADVRIYKQKPFQAPEFPSPPIKVKKVPRTKIEKVKYEYVSKSNGAVSSGGRGDLLPRSKSEVGKSMGSIAGCPEKDTHLDSFSVTTEIKINCEMKTSGVCDIKKAGCYKENLRHLISSGEIVSMADRFSSGERRPAENGQGCAEMARVKVEISPFKENTLKACQMLVNGTHNDNQDTDYNRSAKEIMLENSLRSNNNKLIKLRAKKKKKKKKKLKDILNENLQKKLDDLQRRREVHLYPFKSYKSEIQSKLFKKKAKHKKHKSGKKSVSKKAITKKRKGVTKSAIPEFQLICTNLDELRELITKIENELKDLEDIKKKSGRWYHRKQAVKELHGTLIRLLNELLPWEPKLMKAFQRNRSRLKKDYDEFKRHPDHDKFTRELWSNDESEVDAGKDCFAIVSSKSSESAEYVEIPRKDHPDNDEMKLLEMNLPAGKSKLLKKESTSKEIHKTLLKSFKRQSKQNSCLDQNTNELSPRKKAKLSTSEAAVQSSESSLQTDSCLTDLKQLEGSSPESFSLTDPATSVSSFLKGTKPIQALLAKNIGNKVTLTNQLSPPPGINVSTSEKPVLSPVESSLIKPALPCQTGSKTPLQMVYKMPNGHCVPVDLHNSSVKIQMQPVIDPKTGEKVMQQVLILPKNFLLQQKEGKVMSKDSNLLQQNSSELHCATFPEITNVTVSLTPVLVTAPANVTSHSTSTIFNKNICNLSQGTVSTNSTQTLPTTTSSLVSSTVKVCQTEHDKLRTEVSTTTFPVFLSSPSISTASQSLISATALSASTNTATAFHCLASQQATESFETRQELKTVCIRESQSILVTTRGGNTGIVKVQTNPDQISPTSISSGSVLTYASQFKAFLVPKTTALSSSTLPSVATATSSLPHFGQSSVSGFAPSTGSSFNTPPFPADFNQAVDKSIKFTLQQPATGSSLGQVVENTCQVSCPSSSCISSASSSISATPNSPISVTSTSQNNTVVTPNSSVQQQCDTKTKTNSVIQSESSSVINGDFISGTPVQKLTLVTNPPILSPCGASGVSVIPSLAPTGVSAQKLVFINTPIPNGPSATTLVAESLKHNLPSSISKTFVSATEQPQLVLIPSTMGAPIRINSSPTIAQVKDVKIGLNIGQTIVNTKGSAQQTPPVNILHSAVSKGEDKKNIGLALSLTSTNSLVPVCSSFISQSAVSINESLCVAAKATNSFSVPTANACPESVSVAPSGTSGTRPTVLSGGNDPSKVRPVLGSRLCTANIGNTVGISTVKTGHLASSVLISTTQPMVSSQNLTSALQFPVISLSGSVATPRKVLHTVPQLAAVPAPPPVPKSQLPTLLQFQSSGVTAAGPSNAGTQKPQSLLTPASPNTGKVVSFPSFSSLQCKQVPPSLEKQSPAYSVASTIQMCVASPAITSKTGGQLNEPCIQQKIVINTCMPLAPGTQIMINGTCFVVPPQGLGAGSHVLLLSYNTKQTPPLNINHGQEAQGVPVVNPITSKIILAPSNSLSWQTSQRLLKNSTKIVNSFGSADALPIVHATPQILSTPSSSCTPLPAATLSVSSVIKSPAYVPTTSSVVSAVHPSNSHLPSNTSVFQLDTSIKKLLVSPEGAILNAINTPASKVSSLSSSLPPVVVSTSRISTTVFPISQSSCLDKPDNAAS", "length": 2119 }, "evidence": [ { "id": "G3MZW1", "url": "https://omabrowser.org/oma/group/G3MZW1/", "database": "OMA" } ], "glygen_name": "Chicken", "common_name": "Chicken" }, { "uniprot_canonical_ac": "F1LRC7-1", "protein_name": "Bromodomain containing 10", "gene_name": "Brd10", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MSVPETPGEMERAAEEERPPPPTGEGNEEEVVAAAARASGLVRRRSASSVDDEEEEAAAETTVVAGGGCKEQELTYELQQGYRILGEFLQEKHRGLTAPFLQPLGGVAAGEEEVAEGRRSGGRGSRVPPQQPGQGMCLLKMEEKFSSGQYRGITEFVADFRLMLETCYRLHGVDHWISKQGQKLEMLLEQKLALLSRHLREKTTIAVTSRGYYGLEEEKGTACTSTRRRSTPRSLAGLTSGVFESIMVQVLRQEEQLRAKEEKRLREQERKEAEEACQKEVEEWERKLLAQAAPACMENMWEIPAIGHFLCLAQQILNLPEIVFYELERCLLMPQCNAFLSKIMTSLLSPPHRRPTLHRRPTLPYRTWEAVLRQKVRQWYTAVGQTENPGNCAEKLGLCPQFFKVLGEVNPLEERPFHELPFYQKVWLLKGLCDFVYETQKEVQDAVLGQPIHECREVILGYDYLENAYVHFPQFCGADVRIYKQRPFQAPEFPVPPIKVKRVPRIKLEKFKCDYVNTSNGEHRCNREGLPLTFKKEQEIDFDPAYCPAKMNFDNHDITVEVEVKANCDIKVHRPCEIEKTDCCKENLQKPRSPGEVTGFGEPLSPGEIRFIENQEKYGEASKIKTESNPLKENALKSCQIHINGSHIDHPDINCRKAVRDILLEHSLQSHKKLKLTKMRAKKKKKKKKKLKDVLSENLQRKREGLHSLPFKSYKPEIQSKLLIIKKKGKHKKHKSGKKSISKKAITKKRKTVTKSPAVPEFQLICTNLDELRELITKIENELKDLENSRKKSGRWYHRRQAVKELHSTLIRLLNELLPWEPKLMKAFQRNRSRLKKDYDDFRRQPDHGQFTRELWTTEESEGHPEREAPKAELSKSVDAAEPLDSLDKEREDSDDMKLSDIGFPMARSKLLKKELPSKDTVKTLPKALKRQSKQSSCPDDSAEELSPRKRARLSTSEPSAENLDVEMPIDCLSECKPAELPFQESFASKDSVPVSTLQKGTKPIQALLAKNIGNKVTLTNQLPPSTGRSVPAVEKPAPSPAETSPIKPALTCLTSTKGPLQMVYKIPCGQWLPVDLHSSSVKIQMQPVVDSKTGEKIMQQVLILPKNFVIQHKEGKAVAKEIAAPQQKGAEHCSPCPQTTSVNCSLVSVPVTSVCTQLPDTVLNKTVTLSSNVSARSQPLSPVTSVSNVLISPVKTSQSEAGKVKSTVSSNTFPQSNTSPTISSTVQPLLPATTLNEFTDPGSSLPCFSQQTVDSSEAKQELKTVCIRDSQSILVRTRGGNTGVVKVQTNPEQNSPNSLSSSSVFTFAPQFQAFLVPKSTSCPTSSQVAGVTATSSLPSFSQAPTSMSITCGSHPPVGKNLKSTVGQTFSSGYAGPMIEKMPCMPSSPLKPSISSSSLLPPPTNSSVSVISISAGNFGQSNASVIHTSTKPQQVDCITKSYPVTGSEATTAINGDVLSVVSAPPLPPPGSAPSAAVAPAPASAGASTQKVVFINAPAPSGTSSSALVAESLKQTLPSPLSKTYVKNPEQPQIVLIPSTVGAPRKVNSSPAVSQIKDVKIGLNIGQAIINPPGNLPAVSSINILQSVMPKAEDKSNKGCISPISPSSNSVPASSNIVSQTLPPASESARAANTFSGIAANVPLSSLSVTSSPASVGTRPPVLVSGNDTSSRIMPVLSNRLCTSNLGNTVAISTVKTGHLASSVLISTTQPAVSPRCLTSALQIPVTVALPPPVTTSPKIINTAPQSAAVPGATHPVSLPKKQSRTSLQFQSPGTTATVPTNANTTKPPAEFSSPSPSPGKIVSISNVPSVPNQHVPPSLVKTTLSNNSLAGGSAIHTCSPPSNITGLAGAPFTEPCIQQKIVINTSTPLAPGTQIMMNGARFIVPPQGLGAGSHVLLIATNPKYGPPLLLNSGQSILATPVDNPVQKIIQTSNSSLSGQPLKHSVRNSTKIVNSFGSPSSLSAVHTAPHIVNTPAKACVPPAPPAPLTSVIKASPAALLAKTSLVSAVSPSNPPLPSSTSVFHLDTSVKKLLVSPEGAILNTINTPAAKAPSLSSSLPPVVTASQNPAPVFPAFPSSGLEKPDTAAS", "length": 2087 }, "evidence": [ { "id": "G3MZW1", "url": "https://omabrowser.org/oma/group/G3MZW1/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "H3BKP8-1", "protein_name": "Bromodomain containing 10", "gene_name": "Brd10", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": 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"length": 2027 }, "evidence": [ { "id": "G3MZW1", "url": "https://omabrowser.org/oma/group/G3MZW1/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q5HYC2-1", "protein_name": "Uncharacterized bromodomain-containing protein 10", "gene_name": "BRD10", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": 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"length": 2103 }, "evidence": [ { "id": "G3MZW1", "url": "https://omabrowser.org/oma/group/G3MZW1/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" } ], "go_annotation": {}, "pro_annotation": [], "site_annotation": [ { "start_pos": 1011, "end_pos": 1013, "annotation": "n_glycosylation_sequon" }, { "start_pos": 1077, "end_pos": 1079, "annotation": "n_glycosylation_sequon" }, { "start_pos": 1101, "end_pos": 1103, "annotation": "n_glycosylation_sequon" }, { "start_pos": 1109, "end_pos": 1111, "annotation": "n_glycosylation_sequon" }, { "start_pos": 1174, "end_pos": 1176, "annotation": "n_glycosylation_sequon" }, { "start_pos": 1178, "end_pos": 1180, "annotation": "n_glycosylation_sequon" }, { "start_pos": 1343, "end_pos": 1345, "annotation": "n_glycosylation_sequon" }, { "start_pos": 1350, "end_pos": 1352, "annotation": "n_glycosylation_sequon" }, { "start_pos": 1491, "end_pos": 1493, "annotation": "n_glycosylation_sequon" }, { "start_pos": 1514, "end_pos": 1516, "annotation": "n_glycosylation_sequon" }, { "start_pos": 1530, "end_pos": 1532, "annotation": "n_glycosylation_sequon" }, { "start_pos": 1564, "end_pos": 1566, "annotation": "n_glycosylation_sequon" }, { "start_pos": 1569, "end_pos": 1571, "annotation": "n_glycosylation_sequon" }, { "start_pos": 1588, "end_pos": 1590, "annotation": "n_glycosylation_sequon" }, { "start_pos": 1614, "end_pos": 1616, "annotation": "n_glycosylation_sequon" }, { "start_pos": 1751, "end_pos": 1753, "annotation": "n_glycosylation_sequon" }, { "start_pos": 1791, "end_pos": 1793, "annotation": "n_glycosylation_sequon" }, { "start_pos": 1812, "end_pos": 1814, "annotation": "n_glycosylation_sequon" }, { "start_pos": 1881, "end_pos": 1883, "annotation": "n_glycosylation_sequon" }, { "start_pos": 1905, "end_pos": 1907, "annotation": "n_glycosylation_sequon" }, { "start_pos": 1967, "end_pos": 1969, "annotation": "n_glycosylation_sequon" }, { "start_pos": 510, "end_pos": 512, "annotation": "n_glycosylation_sequon" }, { "start_pos": 575, "end_pos": 577, "annotation": "n_glycosylation_sequon" }, { "start_pos": 762, "end_pos": 764, "annotation": "n_glycosylation_sequon" }, { "start_pos": 889, "end_pos": 891, "annotation": "n_glycosylation_sequon" }, { "start_pos": 906, "end_pos": 908, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "G3MZW1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3MZW1" }, { "id": "PF23450", "database": "Pfam", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF23450" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "Uncharacterized bromodomain-containing protein 10 helical", "eco_id": "ECO_0000259", "start_pos": 233, "end_pos": 374, "start_aa": "Glu", "end_aa": "Val", "glycosite_overlap": [] } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" }, { "name": "homologset.oma", "label": "OMA Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [ 1426, 1777, 1867, 1933 ], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 1011, "end_pos": 1013 }, { "start_pos": 1077, "end_pos": 1079 }, { "start_pos": 1101, "end_pos": 1103 }, { "start_pos": 1109, "end_pos": 1111 }, { "start_pos": 1174, "end_pos": 1176 }, { "start_pos": 1178, "end_pos": 1180 }, { "start_pos": 1343, "end_pos": 1345 }, { "start_pos": 1350, "end_pos": 1352 }, { "start_pos": 1491, "end_pos": 1493 }, { "start_pos": 1514, "end_pos": 1516 }, { "start_pos": 1530, "end_pos": 1532 }, { "start_pos": 1564, "end_pos": 1566 }, { "start_pos": 1569, "end_pos": 1571 }, { "start_pos": 1588, "end_pos": 1590 }, { "start_pos": 1614, "end_pos": 1616 }, { "start_pos": 1751, "end_pos": 1753 }, { "start_pos": 1791, "end_pos": 1793 }, { "start_pos": 1812, "end_pos": 1814 }, { "start_pos": 1881, "end_pos": 1883 }, { "start_pos": 1905, "end_pos": 1907 }, { "start_pos": 1967, "end_pos": 1969 }, { "start_pos": 510, "end_pos": 512 }, { "start_pos": 575, "end_pos": 577 }, { "start_pos": 762, "end_pos": 764 }, { "start_pos": 889, "end_pos": 891 }, { "start_pos": 906, "end_pos": 908 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 4 }, { "field": "total_sites", "count": 4 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 4 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "exact_sites", "count": 4 }, { "field": "exact_o_linked_sites", "count": 4 }, { "field": "fuzzy_sites", "count": 0 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_pos", "start_aa", "end_pos", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 4 }, { "field": "total_sites", "count": 4 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 4 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "exact_sites", "count": 4 }, { "field": "exact_o_linked_sites", "count": 4 }, { "field": "fuzzy_sites", "count": 0 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_pos", "start_aa", "end_pos", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ], "tool_support": { "graph_view": "yes" } }, { "uniprot_canonical_ac": "F6RMB4-1", "uniprot_ac": "F6RMB4", "uniprot_id": "F6RMB4_BOVIN", "mass": { "chemical_mass": 38580.0, "monoisotopic_mass": 38580.0 }, "refseq": { "ac": "XP_010803179", "name": "poly(rC)-binding protein 2 isoform X19", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_010803179" }, "gene_names": [ { "name": "PCBP2", "type": "recommended", "evidence": [ { "id": "F6RMB4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F6RMB4" } ] }, { "name": "PCBP2", "type": "synonym", "evidence": [ { "id": "XP_010803179", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_010803179" } ] } ], "protein_names": [ { "name": "Poly(rC) binding protein 2", "type": "synonym", "evidence": [ { "id": "F6RMB4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F6RMB4/entry#names_and_taxonomy" } ] }, { "name": "poly(rC)-binding protein 2 isoform X19", "type": "synonym", "evidence": [ { "id": "XP_010803179", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_010803179" } ] } ], "function": [], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Bos taurus", "taxid": 9913, "evidence": [ { "database": "UniProtKB", "id": "F6RMB4", "url": "https://www.uniprot.org/uniprotkb/F6RMB4" } ], "common_name": "Bovine", "glygen_name": "Bovine", "reference_species": "Bos taurus [9913]" } ], "gene": [ { "name": "PCBP2", "url": "https://www.uniprot.org/uniprotkb/F6RMB4", "locus": { "chromosome": "5", "start_pos": 26541065, "end_pos": 26564985, "strand": "+", "evidence": [ { "database": "Ensembl Gene", "id": "ENSBTAG00000020757", "url": "https://www.ensembl.org/id/ENSBTAG00000020757" } ] } } ], "crossref": [ { "id": "F6RMB4", "url": "https://alphafold.ebi.ac.uk/entry/F6RMB4", "database": "AlphaFoldDB", "categories": [] }, { "id": "ENSBTAG00000020757", "url": "https://bgee.org/?page=gene&gene_id=ENSBTAG00000020757", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "cd22515", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd22515", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "cd22518", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd22518", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "cd22521", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd22521", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "540653", "url": "https://www.ncbi.nlm.nih.gov/gene/540653", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR004087", "url": "https://www.ebi.ac.uk/interpro/entry/IPR004087", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR004088", "url": "https://www.ebi.ac.uk/interpro/entry/IPR004088", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR036612", "url": "https://www.ebi.ac.uk/interpro/entry/IPR036612", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "A0A3Q1LPY4", "url": "https://www.orthodb.org/?gene=A0A3Q1LPY4", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A3Q1LX34", "url": "https://www.orthodb.org/?gene=A0A3Q1LX34", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A3Q1M0T4", "url": "https://www.orthodb.org/?gene=A0A3Q1M0T4", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A3Q1MDS1", "url": "https://www.orthodb.org/?gene=A0A3Q1MDS1", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A3Q1MU31", "url": "https://www.orthodb.org/?gene=A0A3Q1MU31", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR10288", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR10288", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00013", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00013", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "R-BTA-72163", "url": "https://www.reactome.org/PathwayBrowser/#R-BTA-72163", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "R-BTA-72203", "url": "https://www.reactome.org/PathwayBrowser/#R-BTA-72203", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "R-BTA-9770562", "url": "https://www.reactome.org/PathwayBrowser/#R-BTA-9770562", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "XP_010803179", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_010803179", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A3Q1LPY4", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1LPY4", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A3Q1LPY4-1", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1LPY4-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A3Q1LX34", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1LX34", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A3Q1LX34-1", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1LX34-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A3Q1M0T4", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1M0T4", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A3Q1M0T4-1", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1M0T4-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A3Q1MDS1", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1MDS1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A3Q1MDS1-1", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1MDS1-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A3Q1MU31", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1MU31", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A3Q1MU31-1", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1MU31-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0AAA9RXW5", "url": "https://www.uniprot.org/uniprotkb/A0AAA9RXW5", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0AAA9RXW5-1", "url": "https://www.uniprot.org/uniprotkb/A0AAA9RXW5-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0AAA9SYD5", "url": "https://www.uniprot.org/uniprotkb/A0AAA9SYD5", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0AAA9SYD5-1", "url": "https://www.uniprot.org/uniprotkb/A0AAA9SYD5-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0AAA9SYQ5", "url": "https://www.uniprot.org/uniprotkb/A0AAA9SYQ5", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0AAA9SYQ5-1", "url": "https://www.uniprot.org/uniprotkb/A0AAA9SYQ5-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "F6RMB4", "url": "https://www.uniprot.org/uniprotkb/F6RMB4", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "F6RMB4-1", "url": "https://www.uniprot.org/uniprotkb/F6RMB4-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MDTGVIEGGLNVTLTIRLLMHGKEVGSIIGKKGESVKKMREESGARINISEGNCPERIITLAGPTNAIFKAFAMIIDKLEEDISSSMTNSTAASRPPVTLRLVVPASQCGSLIGKGGCKIKEIRESTGAQVQVAGDMLPNSTERAITIAGIPQSIIECVKQICVVMLETLSQSPPKGVTIPYRPKPSSSPVIFAGGQDRYSTGSDSASFPHTTPSMCLNPDLEGPPLEAYTIQGQYAIPQPDLTKLHQLAMQQSHFPMTHGNTGFSGIESSSPEVKGYWGLDASAQTTSHELTIPNDLIGCIIGRQGAKINEIRQMSGAQIKIANPVEGSTDRQVTITGSAASISLAQYLINVRLSSETGGMGSS", "length": 365, "header": "tr|F6RMB4-1|F6RMB4_BOVIN Isoform 1 of Poly(rC) binding protein 2 OS=Bos taurus OX=9913 GN=PCBP2 PE=1 SV=1 CANONICAL=F6RMB4-1" }, "isoforms": [ { "isoform_ac": "A0A3Q1LPY4-1", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1LPY4/entry", "sequence": { "sequence": "MDTGVIEGGLNVTLTIRLLMHGKEVGSIIGKKGESVKKMREESGARINISEGNCPERIITLAGPTNAIFKAFAMIIDKLEEDISSSMTNSTAASRPPVTLRLVVPASQCGSLIGKGGCKIKEIRESTGAQVQVAGDMLPNSTERAITIAGIPQSIIECVKQICVVMLETLSQSPPKGVTIPYRPKPSSSPVIFAGGQDRYSTGSDSASFPHTTPSMCLNPDLEGPPLEAYTIQGQYAIPQPDLTKLHQLAMQQSHFPMTHGNTGFSGIESSSPEVKGYWAGLDASAQTTSHELTIPNDLIGCIIGRQGAKINEIRQMSGAQIKIANPVEGSTDRQVTITGSAASISLAQYLINVRLSSETGGMGSS", "length": 366, "header": "tr|A0A3Q1LPY4-1|F6RMB4_BOVIN Computationally mapped isoform of Poly(rC) binding protein 2 OS=Bos taurus OX=9913 GN=PCBP2 PE=1 SV=2 CANONICAL=F6RMB4-1" }, "locus": { "chromosome": "5", "start_pos": 26559786, "end_pos": 26541447, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000085161.2", "url": "https://www.ensembl.org/id/ENSBTAT00000085161.2" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000059082.2", "url": "https://www.ensembl.org/id/ENSBTAP00000059082.2" } ] } }, { "isoform_ac": "A0A3Q1LX34-1", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1LX34/entry", "sequence": { "sequence": "MDTGVIEGGLNVTLTIRLLMHGKEVGSIIGKKGESVKKMREESGARINISEGNCPERIITLAGPTNAIFKAFAMIIDKLEEDISSSMTNSTAASRPPVTLRLVVPASQCGSLIGKGGCKIKEIRESTGAQVQVAGDMLPNSTERAITIAGIPQSIIECVKQICVVMLESPPKGVTIPYRPKPSSSPVIFAGGQDRYSTGSDSASFPHTTPSMCLNPDLEGPPLEAYTIQGQYAIPQPDLTKLHQLAMQQSHFPMTHGNTGFSAGLDASAQTTSHELTIPNDLIGCIIGRQGAKINEIRQMSGAQIKIANPVEGSTDRQVTITGSAASISLAQYLINVSLENAKPSSQAASVTIPDHLSINLSQPSTPSSSSSSSTTTPSLATAGTSDAPSSLPNPLPTAPCVSSLLGMKPIPLLALNVVSAAKGTGASATTTTTSAVPCVTNKLKGEKQRFSPY", "length": 454, "header": "tr|A0A3Q1LX34-1|A0A3Q1LX34_BOVIN Computationally mapped isoform of Poly(rC) binding protein 2 OS=Bos taurus OX=9913 GN=PCBP2 PE=1 SV=2 CANONICAL=F6RMB4-1" }, "locus": { "chromosome": "5", "start_pos": 26559786, "end_pos": 26544515, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000078611.2", "url": "https://www.ensembl.org/id/ENSBTAT00000078611.2" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000065293.2", "url": "https://www.ensembl.org/id/ENSBTAP00000065293.2" } ] } }, { "isoform_ac": "A0A3Q1M0T4-1", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1M0T4/entry", "sequence": { "sequence": "MDTGVIEGGLNVTLTIRLLMHGKEVGSIIGKKGESVKKMREESGARINISEGNCPERIITLAGPTNAIFKAFAMIIDKLEEDISSSMTNSTAASRPPVTLRLVVPASQCGSLIGKGGCKIKEIRESTGAQVQVAGDMLPNSTERAITIAGIPQSIIECVKQICVVMLESPPKGVTIPYRPKPSSSPVIFAGGQDRYSTGSDSASFPHTTPSMCLNPDLEGPPLEAYTIQGQYAIPQPDLTKLHQLAMQQSHFPMTHGNTGFSAGLDASAQTTSHELTIPNDLIGCIIGRQGAKINEIRQMSGAQIKIANPVEGSTDRQVTITGSAASISLAQYLINVRWSLPALAKQDFEAVWAAGGHR", "length": 359, "header": "tr|A0A3Q1M0T4-1|F6RMB4_BOVIN Computationally mapped isoform of Poly(rC) binding protein 2 OS=Bos taurus OX=9913 GN=PCBP2 PE=1 SV=3 CANONICAL=F6RMB4-1" }, "locus": { "chromosome": "5", "start_pos": 26559786, "end_pos": 26536195, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000074083.3", "url": "https://www.ensembl.org/id/ENSBTAT00000074083.3" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000063275.3", "url": "https://www.ensembl.org/id/ENSBTAP00000063275.3" } ] } }, { "isoform_ac": "A0A3Q1MDS1-1", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1MDS1/entry", "sequence": { "sequence": "MDTGVIEGGLNVTLTIRLLMHGKEVGSIIGKKGESVKKMREESGARINISEGNCPERIITLAGPTNAIFKAFAMIIDKLEEDISSSMTNSTAASRPPVTLRLVVPASQCGSLIGKGGCKIKEIRESTGAQVQVAGDMLPNSTERAITIAGIPQSIIECVKQICVVMLESPPKGVTIPYRPKPSSSPVIFAGGQDRYSTGSDSASFPHTTPSMCLNPDLEGPPLELTKLHQLAMQQSHFPMTHGNTGFSGIESSSPEVKGYWGLDASAQTTSHELTIPNDLIGCIIGRQGAKINEIRQMSGAQIKIANPVEGSTDRQVTITGSAASISLAQYLINVRLSSETGGMGSS", "length": 347, "header": "tr|A0A3Q1MDS1-1|F6RMB4_BOVIN Computationally mapped isoform of Poly(rC) binding protein 2 OS=Bos taurus OX=9913 GN=PCBP2 PE=1 SV=2 CANONICAL=F6RMB4-1" }, "locus": { "chromosome": "5", "start_pos": 26559786, "end_pos": 26541447, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000083243.2", "url": "https://www.ensembl.org/id/ENSBTAT00000083243.2" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000072284.2", "url": "https://www.ensembl.org/id/ENSBTAP00000072284.2" } ] } }, { "isoform_ac": "A0A3Q1MU31-1", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1MU31/entry", "sequence": { "sequence": "MDTGVIEGGLNVTLTIRLLMHGKVCNSLGNWKGESVKKMREESGARINISEGNCPERIITLAGPTNAIFKAFAMIIDKLEEDISSSMTNSTAASRPPVTLRLVVPASQCGSLIGKGGCKIKEIRESTGAQVQVAGDMLPNSTERAITIAGIPQSIIECVKQICVVMLEVSPQGVTIPYRPKPSSSPVIFAGGQVRSSDSASFPHTTPSMCLNPDLEGPPLEVRGDLTKLHQLAMQQSHFPMTHGNTGFSGIESSSPEVKGYWAMQLLIWYALFFFLKLIGCIIGRQGAKINEIRQMSGAQIKIANPVEGSTDRQVTITGSAASISLAQYLINGRDCKRKSI", "length": 341, "header": "tr|A0A3Q1MU31-1|F6RMB4_BOVIN Computationally mapped isoform of Poly(rC) binding protein 2 OS=Bos taurus OX=9913 GN=PCBP2 PE=1 SV=2 CANONICAL=F6RMB4-1" }, "locus": { "chromosome": "5", "start_pos": 26559786, "end_pos": 26547193, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000080318.2", "url": "https://www.ensembl.org/id/ENSBTAT00000080318.2" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000074020.2", "url": "https://www.ensembl.org/id/ENSBTAP00000074020.2" } ] } }, { "isoform_ac": "A0AAA9RXW5-1", "url": "https://www.uniprot.org/uniprotkb/A0AAA9RXW5/entry", "sequence": { "sequence": "MDTGVIEGGLNVTLTIRLLMHGKEVGSIIGKKGESVKKMREESGARINISEGNCPERIITLAGPTNAIFKAFAMIIDKLEEDISSSMTNSTAASRPPVTLRLVVPASQCGSLIGKGGCKIKEIRESTGAQVQVAGDMLPNSTERAITIAGIPQSIIECVKQICVVMLESPPKGVTIPYRPKPSSSPVIFAGGQLTKLHQLAMQQSHFPMTHGNTGFSGIESSSPEVKGYWAGLDASAQTTSHELTIPNDLIGCIIGRQGAKINEIRQMSGAQIKIANPVEGSTDRQVTITGSAASISLAQYLINVSLENAKPSSQAASVTIPDHLSINLSQPSTPSSSSSSSTTTPSLATAGTSDAPSSLPNPLPTAPCVSSLLGMKPIPLLALNVVSAAKGTGASATTTTTSAVPCVTNKLKGEKQRFSPY", "length": 422, "header": "tr|A0AAA9RXW5-1|F6RMB4_BOVIN Computationally mapped isoform of Poly(rC) binding protein 2 OS=Bos taurus OX=9913 GN=PCBP2 PE=1 SV=1 CANONICAL=F6RMB4-1" }, "locus": { "chromosome": "5", "start_pos": 26559786, "end_pos": 26544515, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000126573.2", "url": "https://www.ensembl.org/id/ENSBTAT00000126573.2" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000078377.1", "url": "https://www.ensembl.org/id/ENSBTAP00000078377.1" } ] } }, { "isoform_ac": "A0AAA9SYD5-1", "url": "https://www.uniprot.org/uniprotkb/A0AAA9SYD5/entry", "sequence": { "sequence": "MDTGVIEGGLNVTLTIRLLMHGKEVGSIIGKKGESVKKMREESGARINISEGNCPERIITLAGPTNAIFKAFAMIIDKLEEDISSSMTNSTAASRPPVTLRLVVPASQCGSLIGKGGCKIKEIRESTGAQVQVAGDMLPNSTERAITIAGIPQSIIECVKQICVVMLESPPKGVTIPYRPKPSSSPVIFAGGQDRYSTGSDSASFPHTTPSMCLNPDLEGPPLEAYTIQGQYAIPQPDLTKLHQLAMQQSHFPMTHGNTGFSGIESSSPEVKGYWAGLDASAQTTSHELTIPNDLIGCIIGRQGAKINEIRQMSGAQIKIANPVEGSTDRQVTITGSAASISLAQYLINVSLENAKPSSQAASVTIPDHLSINLSQPSTPSSSSSSSTTTPSLATAGTSDAPSSLPNPLPTAPCVSSLLGMKPIPLLALNVVSAAKGTGASATTTTTSAVPCVTNKLKGEKQRFSPY", "length": 467, "header": "tr|A0AAA9SYD5-1|F6RMB4_BOVIN Computationally mapped isoform of Poly(rC) binding protein 2 OS=Bos taurus OX=9913 GN=PCBP2 PE=1 SV=1 CANONICAL=F6RMB4-1" }, "locus": { "chromosome": "5", "start_pos": 26559786, "end_pos": 26544515, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000126765.2", "url": "https://www.ensembl.org/id/ENSBTAT00000126765.2" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000090377.1", "url": "https://www.ensembl.org/id/ENSBTAP00000090377.1" } ] } }, { "isoform_ac": "A0AAA9SYQ5-1", "url": "https://www.uniprot.org/uniprotkb/A0AAA9SYQ5/entry", "sequence": { "sequence": "MDTGVIEGGLNVTLTIRLLMHGKEVGSIIGKKGESVKKMREESGARINISEGNCPERIITLAGPTNAIFKAFAMIIDKLEEDISSSMTNSTAASRPPVTLRLVVPASQCGSLIGKGGCKIKEIRESTGAQVQVAGDMLPNSTERAITIAGIPQSIIECVKQICVVMLESPPKGVTIPYRPKPSSSPVIFAGGQAYTIQGQYAIPQPDLTKLHQLAMQQSHFPMTHGNTGFSGIESSSPEVKGYWAGLDASAQTTSHELTIPNDLIGCIIGRQGAKINEIRQMSGAQIKIANPVEGSTDRQVTITGSAASISLAQYLINVSLENAKPSSQAASVTIPDHLSINLSQPSTPSSSSSSSTTTPSLATAGTSDAPSSLPNPLPTAPCVSSLLGMKPIPLLALNVVSAAKGTGASATTTTTSAVPCVTNKLKGEKQRFSPY", "length": 436, "header": "tr|A0AAA9SYQ5-1|F6RMB4_BOVIN Computationally mapped isoform of Poly(rC) binding protein 2 OS=Bos taurus OX=9913 GN=PCBP2 PE=1 SV=1 CANONICAL=F6RMB4-1" }, "locus": { "chromosome": "5", "start_pos": 26559786, "end_pos": 26544515, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000102173.2", "url": "https://www.ensembl.org/id/ENSBTAT00000102173.2" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000090501.1", "url": "https://www.ensembl.org/id/ENSBTAP00000090501.1" } ] } }, { "isoform_ac": "F6RMB4-1", "url": "https://www.uniprot.org/uniprotkb/F6RMB4/entry", "sequence": { "sequence": "MDTGVIEGGLNVTLTIRLLMHGKEVGSIIGKKGESVKKMREESGARINISEGNCPERIITLAGPTNAIFKAFAMIIDKLEEDISSSMTNSTAASRPPVTLRLVVPASQCGSLIGKGGCKIKEIRESTGAQVQVAGDMLPNSTERAITIAGIPQSIIECVKQICVVMLETLSQSPPKGVTIPYRPKPSSSPVIFAGGQDRYSTGSDSASFPHTTPSMCLNPDLEGPPLEAYTIQGQYAIPQPDLTKLHQLAMQQSHFPMTHGNTGFSGIESSSPEVKGYWGLDASAQTTSHELTIPNDLIGCIIGRQGAKINEIRQMSGAQIKIANPVEGSTDRQVTITGSAASISLAQYLINVRLSSETGGMGSS", "length": 365, "header": "tr|F6RMB4-1|F6RMB4_BOVIN Isoform 1 of Poly(rC) binding protein 2 OS=Bos taurus OX=9913 GN=PCBP2 PE=1 SV=1 CANONICAL=F6RMB4-1" }, "locus": { "chromosome": "5", "start_pos": 26559786, "end_pos": 26541447, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000027662.6", "url": "https://www.ensembl.org/id/ENSBTAT00000027662.6" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000027662.5", "url": "https://www.ensembl.org/id/ENSBTAP00000027662.5" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [ { "id": "R-BTA-72163", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-BTA-72163", "resource": "Reactome", "description": "mRNA Splicing - Major Pathway" }, { "id": "R-BTA-72203", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-BTA-72203", "resource": "Reactome", "description": "Processing of Capped Intron-Containing Pre-mRNA" }, { "id": "R-BTA-9770562", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-BTA-9770562", "resource": "Reactome", "description": "mRNA Polyadenylation" } ], "orthologs": [], "go_annotation": { "categories": [ { "name": "Molecular Function", "total": 7, "go_terms": [ { "name": "DNA binding", "id": "GO:0003677", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003677", "evidence": [ { "database": "UniProtKB", "id": "F6RMB4", "url": "https://www.uniprot.org/uniprotkb/F6RMB4" } ], "pmid": "" }, { "name": "RNA binding", "id": "GO:0003723", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003723", "evidence": [ { "database": "UniProtKB", "id": "F6RMB4", "url": "https://www.uniprot.org/uniprotkb/F6RMB4" } ], "pmid": "" }, { "name": "ubiquitin protein ligase binding", "id": "GO:0031625", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0031625", "evidence": [ { "database": "UniProtKB", "id": "F6RMB4", "url": "https://www.uniprot.org/uniprotkb/F6RMB4" } ], "pmid": "" }, { "name": "promoter-enhancer loop anchoring activity", "id": 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}, "pro_annotation": [], "site_annotation": [ { "start_pos": 11, "end_pos": 13, "annotation": "n_glycosylation_sequon" }, { "start_pos": 140, "end_pos": 142, "annotation": "n_glycosylation_sequon" }, { "start_pos": 48, "end_pos": 50, "annotation": "n_glycosylation_sequon" }, { "start_pos": 89, "end_pos": 91, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "F6RMB4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F6RMB4" }, { "id": "SM00322", "database": "SMART", "url": "http://smart.embl.de/smart/do_annotation.pl?DOMAIN=SM00322" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "K Homology", "eco_id": "ECO_0000259", "start_pos": 12, "end_pos": 80, "start_aa": "Val", "end_aa": "Glu", "glycosite_overlap": [] } ], "binding_sites": [], 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"reference_species": "Bos taurus [9913]" } ], "gene": [ { "name": "MBIP", "url": "https://www.uniprot.org/uniprotkb/F6RPZ4", "locus": { "chromosome": "21", "start_pos": 46488230, "end_pos": 46507168, "strand": "+", "evidence": [ { "database": "Ensembl Gene", "id": "ENSBTAG00000009941", "url": "https://www.ensembl.org/id/ENSBTAG00000009941" } ] } } ], "crossref": [ { "id": "F6RPZ4", "url": "https://alphafold.ebi.ac.uk/entry/F6RPZ4", "database": "AlphaFoldDB", "categories": [] }, { "id": "ENSBTAG00000009941", "url": "https://bgee.org/?page=gene&gene_id=ENSBTAG00000009941", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "774027", "url": "https://www.ncbi.nlm.nih.gov/gene/774027", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "A0A3Q1LRS8", "url": "https://www.orthodb.org/?gene=A0A3Q1LRS8", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A3Q1M195", "url": "https://www.orthodb.org/?gene=A0A3Q1M195", "database": 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"database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0AAA9SG45", "url": "https://www.uniprot.org/uniprotkb/A0AAA9SG45", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0AAA9SG45-1", "url": "https://www.uniprot.org/uniprotkb/A0AAA9SG45-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0AAA9TRY6", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TRY6", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0AAA9TRY6-1", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TRY6-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0AAA9TX68", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TX68", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0AAA9TX68-1", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TX68-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "F6RPZ4", "url": "https://www.uniprot.org/uniprotkb/F6RPZ4", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "F6RPZ4-1", "url": "https://www.uniprot.org/uniprotkb/F6RPZ4-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MAAAAELSRPTIGDRGLERSCSPSLSREIVCEVFRSLHNLAGQLNLRDDVVKITIDWNKLQSLSALQPAFLFSALEQHVLYLQPFLAKLQPLIKEENTTVAEEIGKTETGNKNEVNANFPIGDLEEEEKHKDSDLGDVKKTQVHFDPEVVQIKAGKAEIDRRISAFIERKQAEINENNVREFCNVIDCNQENSCARTDAIFTPYPGFKSHVKVSRVVNTYGPQTRSEGIPGSGHNPNSMLRDCGNQAVEERLQNIEAHLRLQTGGPVPRDIYQRIKKLEDKILELEGISPEYFQSVNFSGKRRKVQPPQNYSLAELDEKISALKQALLRKSRETESMATRHLP", "length": 343, "header": "tr|F6RPZ4-1|F6RPZ4_BOVIN Isoform 1 of MAP3K12 binding inhibitory protein 1 OS=Bos taurus OX=9913 GN=MBIP PE=4 SV=1 CANONICAL=F6RPZ4-1" }, "isoforms": [ { "isoform_ac": "A0A3Q1LRS8-1", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1LRS8/entry", "sequence": { "sequence": "MAAAAELSRPTIGDRGLERSCSPSLSREIVCEVFRSLHNLAGQLNLRDDVVKITIDWNKLQSLSALQPAFLFSALEQHVLYLQPFLAKLQPLIKEENTTVAEEIGKTETGNKNEVNANFPIGDLEEEEKHKDSDLGDVKKTQVHFDPEVVQIKAGKAEIDRRISAFIERKQAEINENNVREFCNVIDCNQENSCARTDAIFTPYPGFKSHVKVSRVVNTYGPQTRSEGIPGSGHNPNSMLRDCGNQAVEERLQNIEAHLRLQTGGPVPRDIYQRIKKLEDKILELEGISPEYFQSVKPFRGSCINTELFWKKKKSSTTSTELFTG", "length": 325, "header": "tr|A0A3Q1LRS8-1|F6RPZ4_BOVIN Computationally mapped isoform of MAP3K12 binding inhibitory protein 1 OS=Bos taurus OX=9913 GN=MBIP PE=4 SV=2 CANONICAL=F6RPZ4-1" }, "locus": { "chromosome": "21", "start_pos": 46507155, "end_pos": 46488769, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000079015.2", "url": "https://www.ensembl.org/id/ENSBTAT00000079015.2" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000062987.2", "url": "https://www.ensembl.org/id/ENSBTAP00000062987.2" } ] } }, { "isoform_ac": "A0A3Q1M195-1", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1M195/entry", "sequence": { "sequence": "MAAAAELSRPTIGDRGLERSCSPSLSREIVCEVFRSLHNLAGQLNLRDDVVKITIDWNKLQSLSALQPAFLFSALEQHVLYLQPFLAKLQPLIKEENTTVAEEIGKTETGNKNEVNANFPIGDLEEEEKHKDSDLGDVKKTQVHFDPEVVQIKAGKAEIDRRISAFIERKQAEINENNVREFCNVIDCNQENSCARTDAIFTPYPGFKSHVKVSRVVNTYGPQTRSEGIPGSGHNPNSMLRDCGNQAVEERLQNIEAHLRLQTGGPVPRDIYQRIKKLEDKILELEGISPEYFQSVNFSGKRRKVQPPQVISWDLGLEEKGNIN", "length": 324, "header": "tr|A0A3Q1M195-1|F6RPZ4_BOVIN Computationally mapped isoform of MAP3K12 binding inhibitory protein 1 OS=Bos taurus OX=9913 GN=MBIP PE=4 SV=2 CANONICAL=F6RPZ4-1" }, "locus": { "chromosome": "21", "start_pos": 46507155, "end_pos": 46490440, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000070109.2", "url": "https://www.ensembl.org/id/ENSBTAT00000070109.2" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000063470.2", "url": "https://www.ensembl.org/id/ENSBTAP00000063470.2" } ] } }, { "isoform_ac": "A0AAA9SG45-1", "url": "https://www.uniprot.org/uniprotkb/A0AAA9SG45/entry", "sequence": { "sequence": "MAAAAELSRPTIGDRGLERSCSPSLSREIVCEVFRSLHNLAGQLNLRDDVVKITIDWNKLQSLSALQPAFLFSALEQHVLYLQPFLAKLQPLIKEENTTVAEEIGKTETGNKNEVNANFPIGDLEEEEKHKDSDLGDVKKTQVHFDPEVVQIKAGKAEIDRRISAFIERKQAEINENNVREFCNVIDCNQENSCARTDAIFTPYPGFKSHVKVSRVVNTYGPQTRSEGIPGSGHNPNSMLRDCGNQAVEERLQNIEAHLRLQTGGPVPRDIYQRIKKLEDKILELEGISPEYFQSVADGKIATYRVFWCPVQMTTASRRTAS", "length": 322, "header": "tr|A0AAA9SG45-1|F6RPZ4_BOVIN Computationally mapped isoform of MAP3K12 binding inhibitory protein 1 OS=Bos taurus OX=9913 GN=MBIP PE=4 SV=1 CANONICAL=F6RPZ4-1" }, "locus": { "chromosome": "21", "start_pos": 46507155, "end_pos": 46491224, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000089745.1", "url": "https://www.ensembl.org/id/ENSBTAT00000089745.1" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000082632.1", "url": "https://www.ensembl.org/id/ENSBTAP00000082632.1" } ] } }, { "isoform_ac": "A0AAA9TRY6-1", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TRY6/entry", "sequence": { "sequence": 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"database": "Ensembl Peptide", "id": "ENSBTAP00000056207.4", "url": "https://www.ensembl.org/id/ENSBTAP00000056207.4" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [ { "id": "R-BTA-1663150", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-BTA-1663150", "resource": "Reactome", "description": "The activation of arylsulfatases" }, { "id": "R-BTA-9840310", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-BTA-9840310", "resource": "Reactome", "description": "Glycosphingolipid catabolism" } ], "orthologs": [], "go_annotation": { "categories": [ { "name": "Molecular Function", "total": 2, "go_terms": [ { "name": "metal ion binding", "id": "GO:0046872", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0046872", "evidence": [ { "database": "UniProtKB", "id": "G3N2T7", "url": "https://www.uniprot.org/uniprotkb/G3N2T7" } ], "pmid": "" }, { "name": "arylsulfatase activity", "id": "GO:0004065", "url": 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"categories": [ "Protein" ] }, { "id": "G3X8F9-1", "url": "https://www.uniprot.org/uniprotkb/G3X8F9-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "METSGSLQDHSQVHGESEDLDYGETDSHKQDREARLVSQGQDERDKSSSSSSSSSSSSSLSSSSSSSENSDEDQHPRVTRERQHSQGAGLPRRGGSPGAEHGEPDVLKDELQLYEGVPGEVVPSGESGLRRRGSTPMSGKYAGEVEASQLRRLNIKKDDEFFHFILLCFAIGALLVCYHYYTDWFMSLGVGLLTFASLETVGIYFGLVYRIHSVLHGFIPFFQKFRLIGVRKTD", "length": 234, "header": "tr|G3X8F9-1|G3X8F9_BOVIN Isoform 1 of Transmembrane protein 40 OS=Bos taurus OX=9913 GN=TMEM40 PE=4 SV=4 CANONICAL=G3X8F9-1" }, "isoforms": [ { "isoform_ac": "A0AAA9RWK7-1", "url": "https://www.uniprot.org/uniprotkb/A0AAA9RWK7/entry", "sequence": { "sequence": "METSGSLQDHSQVHGESEDLDCAEHGEPDVLKDELQLYEGVPGEVVPSGESGLRRRGSTPMSGEVEASQLRRLNIKKDDEFFHFILLCFAIGALLVCYHYYTDWFMSLGVGLLTFASLETVGIYFGLVYRIHSVLHGFIPFFQKFRLIGVRKTD", "length": 154, "header": "tr|A0AAA9RWK7-1|G3X8F9_BOVIN Computationally mapped isoform of Transmembrane protein 40 OS=Bos taurus OX=9913 GN=TMEM40 PE=4 SV=1 CANONICAL=G3X8F9-1" }, "locus": { "chromosome": "22", "start_pos": 56420503, "end_pos": 56405903, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000092613.2", "url": "https://www.ensembl.org/id/ENSBTAT00000092613.2" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000075483.1", "url": "https://www.ensembl.org/id/ENSBTAP00000075483.1" } ] } }, { "isoform_ac": "A0AAA9TGV0-1", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TGV0/entry", "sequence": { "sequence": "METSGSLQDHSQVHGESEDLDYGETDSHKQDREARLVSQGQDERDKSSSSSSSSSSSSSLSSSSSSSGAEHGEPDVLKDELQLYEGVPGEVVPSGESGLRRRGSTPMSGEVEASQLRRLNIKKDDEFFHFILLCFAIGALLVCYHYYTDWFMSLGVGLLTFASLETVGIYFGLVYRIHSVLHGFIPFFQKFRLIGVRKTD", "length": 200, "header": "tr|A0AAA9TGV0-1|G3X8F9_BOVIN Computationally mapped isoform of Transmembrane protein 40 OS=Bos taurus OX=9913 GN=TMEM40 PE=4 SV=1 CANONICAL=G3X8F9-1" }, "locus": { "chromosome": "22", "start_pos": 56420503, "end_pos": 56405903, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000088408.2", "url": "https://www.ensembl.org/id/ENSBTAT00000088408.2" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000097431.1", "url": "https://www.ensembl.org/id/ENSBTAP00000097431.1" } ] } }, { "isoform_ac": "E1BEX2-1", "url": "https://www.uniprot.org/uniprotkb/E1BEX2/entry", "sequence": { "sequence": "METSGSLQDHSQVHGESEDLDYGETDSHKQDREARLVSQGQDERDKSSSSSSSSSSSSSLSSSSSSSENSDEDQHPRVTRERQHSQGAGLPRRGGSPGAEHGEPDVLKDELQLYEGVPGEVVPSGESGLRRRGSTPMSGEVEASQLRRLNIKKDDEFFHFILLCFAIGALLVCYHYYTDWFMSLGVGLLTFASLETVGIYFGLVYRIHSVLHGFIPFFQKFRLIDL", "length": 226, "header": "tr|E1BEX2-1|G3X8F9_BOVIN Computationally mapped isoform of Transmembrane protein 40 OS=Bos taurus OX=9913 GN=TMEM40 PE=4 SV=4 CANONICAL=G3X8F9-1" }, "locus": { "chromosome": "22", "start_pos": 56438889, "end_pos": 56405903, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000036498.6", "url": "https://www.ensembl.org/id/ENSBTAT00000036498.6" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000036355.5", "url": "https://www.ensembl.org/id/ENSBTAP00000036355.5" } ] } }, { "isoform_ac": "G3X8F9-1", "url": "https://www.uniprot.org/uniprotkb/G3X8F9/entry", "sequence": { "sequence": "METSGSLQDHSQVHGESEDLDYGETDSHKQDREARLVSQGQDERDKSSSSSSSSSSSSSLSSSSSSSENSDEDQHPRVTRERQHSQGAGLPRRGGSPGAEHGEPDVLKDELQLYEGVPGEVVPSGESGLRRRGSTPMSGKYAGEVEASQLRRLNIKKDDEFFHFILLCFAIGALLVCYHYYTDWFMSLGVGLLTFASLETVGIYFGLVYRIHSVLHGFIPFFQKFRLIGVRKTD", "length": 234, "header": "tr|G3X8F9-1|G3X8F9_BOVIN Isoform 1 of Transmembrane protein 40 OS=Bos taurus OX=9913 GN=TMEM40 PE=4 SV=4 CANONICAL=G3X8F9-1" }, "locus": { "chromosome": "22", "start_pos": 56420503, "end_pos": 56405903, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000066256.4", "url": "https://www.ensembl.org/id/ENSBTAT00000066256.4" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000056391.4", "url": "https://www.ensembl.org/id/ENSBTAP00000056391.4" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [ { "id": "bta:505490", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?bta:505490", "resource": "KEGG Pathway" } ], "orthologs": [ { "uniprot_canonical_ac": "D3ZHS0-1", "protein_name": "Transmembrane protein 40", "gene_name": "Tmem40", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MEASGSSSQSPNSSAVHRETEDLNHPETEFHKQHGKARERYERDKSSSSSSSSSSSSSSSSSSSSSSSSGADHGELEVLKDELQLYGGAAGEMVLAGESGLRRRGSGSAEGEVEASQLNRLNIKKDDEFFHFVLLCFAIGALLVCYHYYSDWFMSLGVGLLTFASLETIGIYFGLVYRIHSVLQGFIPLLQKFRLPGFRRTN", "length": 202 }, "evidence": [ { "id": "G3X8F9", "url": "https://omabrowser.org/oma/group/G3X8F9/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "F1SQ88-1", "protein_name": "Transmembrane protein 40", "gene_name": "TMEM40", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "METSGSPQDHSQVHRETEDLDHGETDFHTGLFSQEQHEREKPSSSSSSSSSSSSSSSSSSSGAEHGEPDILKDELQLYGGAPGEVVPSEESGLRRRGCDPASGEVEASQLRRLNIKKDDEFFHFILLCFAIGALLVCYHYYTDWFMSLGVGLLTFASLETVGIYFGLVYRIHSILHGFIPLFQKFRLIGFRKTD", "length": 194 }, "evidence": [ { "id": "G3X8F9", "url": "https://omabrowser.org/oma/group/G3X8F9/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "Q4FJU9-1", "protein_name": "Transmembrane protein 40", "gene_name": "Tmem40", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MEASGSSSQSQDSGGVHRETEDHYQETELHKHHGKARERYKRDKSSSSSSSSSSSSSSSSSSSSSSSDSSDEDQPSRGPRKHRRRPRRDSLRGADHGELEVLKDELQLCGGAAGEMVPTGESGLRRRGSGSAEGEVEASQLRRLNIKKDDEFFHFVLLCFAIGALLVCYHYYADWFMSLGVGLLTFASLETIGIYFGLVYRIHSVLQGFIPLLQKFRLPGFRRTN", "length": 225 }, "evidence": [ { "id": "G3X8F9", "url": "https://omabrowser.org/oma/group/G3X8F9/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q8WWA1-1", "protein_name": "Transmembrane protein 40", "gene_name": "TMEM40", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "METSASSSQPQDNSQVHRETEDVDYGETDFHKQDGKAGLFSQEQYERNKSSSSSSSSSSSSSSSSSSSSSESNDEDQQPRATGKHRRSLGAGYPHGNGSPGPGHGEPDVLKDELQLYGDAPGEVVPSGESGLRRRGSDPASGEVEASQLRRLNIKKDDEFFHFVLLCFAIGALLVCYHYYADWFMSLGVGLLTFASLETVGIYFGLVYRIHSVLQGFIPLFQKFRLTGFRKTD", "length": 233 }, "evidence": [ { "id": "G3X8F9", "url": "https://omabrowser.org/oma/group/G3X8F9/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" } ], "go_annotation": {}, "pro_annotation": [], "site_annotation": [], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [ { "pdb_id": "AF-G3X8F9-F1", "pdb_chain": "global", "start_pos": 1, "end_pos": 234, "overlap": "1.0", "method": "AlphaFold", "type": "alphafold", "resolution": -1.0, "url": "https://data.glygen.org/ln2downloads/pdb/current/AF-G3X8F9-F1.pdb", "url_external": "https://alphafold.ebi.ac.uk/entry/G3X8F9" } ], "lectin_list": [], "domain_list": [], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" }, { "name": "homologset.oma", "label": "OMA Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ], "tool_support": { "graph_view": "yes" } }, { "uniprot_canonical_ac": "G3MWQ8-1", "uniprot_ac": "G3MWQ8", "uniprot_id": "G3MWQ8_BOVIN", "mass": { "chemical_mass": 118152.0, "monoisotopic_mass": 118152.0 }, "refseq": { "ac": "XP_015325852", "name": "cadherin-like and PC-esterase domain-containing protein 1 isoform X1", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_015325852" }, "gene_names": [ { "name": "CPED1", "type": "recommended", "evidence": [ { "id": "G3MWQ8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3MWQ8" } ] }, { "name": "CPED1", "type": "synonym", "evidence": [ { "id": "XP_015325852", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_015325852" } ] } ], "protein_names": [ { "name": "Cadherin like and PC-esterase domain containing 1", "type": "synonym", "evidence": [ { "id": "G3MWQ8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3MWQ8/entry#names_and_taxonomy" } ] }, { "name": "cadherin-like and PC-esterase domain-containing protein 1 isoform X1", "type": "synonym", "evidence": [ { "id": "XP_015325852", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_015325852" } ] } ], "function": [], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Bos taurus", "taxid": 9913, "evidence": [ { "database": "UniProtKB", "id": "G3MWQ8", "url": "https://www.uniprot.org/uniprotkb/G3MWQ8" } ], "common_name": "Bovine", "glygen_name": "Bovine", "reference_species": "Bos taurus [9913]" } ], "gene": [ { "name": "CPED1", "url": "https://www.uniprot.org/uniprotkb/G3MWQ8", "locus": { "chromosome": "4", "start_pos": 85815162, "end_pos": 85490430, "strand": "-", "evidence": [ { "database": "Ensembl Gene", "id": "ENSBTAG00000002938", "url": "https://www.ensembl.org/id/ENSBTAG00000002938" } ] } } ], "crossref": [ { "id": "G3MWQ8", "url": "https://alphafold.ebi.ac.uk/entry/G3MWQ8", "database": "AlphaFoldDB", "categories": [] }, { "id": "ENSBTAG00000002938", "url": "https://bgee.org/?page=gene&gene_id=ENSBTAG00000002938", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "617867", "url": "https://www.ncbi.nlm.nih.gov/gene/617867", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR025883", "url": "https://www.ebi.ac.uk/interpro/entry/IPR025883", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR057106", "url": "https://www.ebi.ac.uk/interpro/entry/IPR057106", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "bta:617867", "url": "https://www.genome.jp/dbget-bin/www_bget?bta:617867", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "HRYTVVI", "url": "https://omabrowser.org/oma/group/HRYTVVI/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "E1BF84", "url": "https://www.orthodb.org/?gene=E1BF84", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "G3MWQ8", "url": "https://www.orthodb.org/?gene=G3MWQ8", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR14776", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR14776", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR14776:SF1", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR14776:SF1", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF12733", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF12733", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF24536", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF24536", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "XP_015325852", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_015325852", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A3Q1N414", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1N414", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A3Q1N414-1", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1N414-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0AAA9SAD9", "url": "https://www.uniprot.org/uniprotkb/A0AAA9SAD9", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0AAA9SAD9-1", "url": "https://www.uniprot.org/uniprotkb/A0AAA9SAD9-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "E1BF84", "url": "https://www.uniprot.org/uniprotkb/E1BF84", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "E1BF84-1", "url": "https://www.uniprot.org/uniprotkb/E1BF84-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "G3MWQ8", "url": "https://www.uniprot.org/uniprotkb/G3MWQ8", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "G3MWQ8-1", "url": "https://www.uniprot.org/uniprotkb/G3MWQ8-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MICRLMFLCRRRFCSRPFLVGLVVAICLFYQTLTLWGTKKLAAAGPGAAPNTPTKTQASRCTKEFFLDKQCFLLSDIAQEIGKIEQSVETHFSSHGRRAVLYRPSSSSQRELQLHRSILTQHHYTVVISEERLGADPGLLEKGDLDSWDLLICLSSKTPGGKPCISKEDMCQLNLHQKVNMLPEIQHQLCRKEGLCQIIKRFPELRLLVSPSVCLNQSIQLKLRTSSHLLKTLKSQMWKPGDWRREQLNQTTALAPQETLLRAKDLSVILKAYVLVTSLTPLRAFIHSAGMVWNPPKKKRFTVKLQTFFETFLRASSPLQAFDTMREAISKLLLAAEVFSETSTLGPKIFQRCRLCFQLLTFDIGYGSVRSPVVLQVHEHLNFQDDDDMAFEDQNIEEFLLKDTFSFLLSNDSSLSIFSEIFQRLYRSAVVKGENYQKELNRCLSLEEINSIMTFIKELRSLGQFQLLFPSTTPGFQSLIGEFYGMTSPMGKPGSILTQYWSLLSVFEQFQLLNKKAEPHPLEWNSFTEDGNIKKPRVPFDAIENKKAVVPQIMNETKEMHCHNDKDAQCHIKQIFTHPRLELNPEFNPKIKDYYSEVPFDVVTLTIGAETSKSQCRVYLQERAGPSFANYSLGLGMNKISVLVVDKSPTQGETLTTYKLTIYREDRPSLPLFEDFTACGFVQDCGLLIQPEETCGLQPISSDYIEAISQPELKTCPSGDTKGQWIVPCLSCSDNRTCDWREITWQPHHCQYGVVTKPQLQQCLGGRKILFIGDSTNRGIMYYLIERLNETLEEWQKVHGTKFYHNVNGGKTLISYSYYPRFWMSPSLRPTFEKALEHLLQRSGPLENTSQTVLVVGGVQWLNSNHLQIIHKVLKREDLLNILVIIKTLGIGFHLPVDGVHFLTQNEVQNLWKKNLIILEDAKKYGYEVVDTFAITMGRHKEFLQGTCGCHFHEVIKSKLSKEDHFLKTKQSRNHIVGKYFSNQSKLQQRRQDSMTNVQSPFHVRGPINQVCSEILLSRICAPERTVEALQKD", "length": 1033, "header": "tr|G3MWQ8-1|G3MWQ8_BOVIN Isoform 1 of Cadherin like and PC-esterase domain containing 1 OS=Bos taurus OX=9913 GN=CPED1 PE=4 SV=1 CANONICAL=G3MWQ8-1" }, "isoforms": [ { "isoform_ac": "A0A3Q1N414-1", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1N414/entry", "sequence": { "sequence": "MICRLMFLCRRRFCSRPFLVGLVVAICLFYQTLTLWGTKKLAAAGPGAAPNTPTKTQASRCTKEFFLDKQCFLLSDIAQEIGKIEQSVETHFSSHGRRAVLYRPSSSSQRELQLHRSILTQHHYTVVISEERLGADPGLLEKGDLDSWDLLICLSSKTPGGKPCISKEDMCQLNLHQKVNMLPEIQHQLCRKEGLCQIIKRFPELRLLVSPSVCLNQSIQLKLRTSSHLLKTLKSQMWKPGDWRREQLNQTTALAPQETLLRAKDLSVILKAYVLVTSLTPLRAFIHSAGMVWNPPKKKRFTVKLQTFFETFLRASSPLQAFDTMREAISKLLLAAEVFSETSTLGPKIFQRCRLCFQLLTFDIGYGSVRSPVVLQVHEHLNFQDDDDMAFEDQNIEEFLLKDTFSFLLSNDSSLSIFSEIFQRLYRSAVVKLFPSTTPGFQSLIGEFYGMTSPMGKPGSILTQYWSLLSVFEQFQLLNKKAEPHPLEWNSFTEDGNIKKPRVPFDAIENKKDKDAQCHIKQIFTHPRLELNPEFNPKIKDYYSEVPFDVVTLTIGAETSKSQCRVYLQERAGPSFANYSLGLGMNKISVLVVDKSPTQGETLTTYKLTIYREDRPSLPLFEDFTACGFVQDCGLLIQPEETCGLQPISSDYIEAISQPELKTCPSGDTKGQWIVPCLSCSDNRTCDWREITWQPHHCQYGVVTKPQLQQCLGGRKILFIGDSTNRGIMYYLIERLNETLEEWQKVHGTKFYHNVNGGKTLISYSYYPRFWMSPSLRPTFEKALEHLLQRSGPLENTSQTVLVVGGVQWLNSNHLQIIHKVLKREDLLNILVIIKTLGIGFHLPVDGVHFLTQNEVQNLWKKNLIILEDAKKYGYEVVDTFAITMGRHKEFLQGTCGCHFHEVIKSKLSKEDHFLKTKQSRNHIVGKYFSNQSKLQQRRQDSMTNVQSPFHVRGPINQVCSEILLSRICAPERTVEALQKD", "length": 981, "header": "tr|A0A3Q1N414-1|G3MWQ8_BOVIN Computationally mapped isoform of Cadherin like and PC-esterase domain containing 1 OS=Bos taurus OX=9913 GN=CPED1 PE=4 SV=2 CANONICAL=G3MWQ8-1" }, "locus": { "chromosome": "4", "start_pos": 85814158, "end_pos": 85492197, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000067297.3", "url": "https://www.ensembl.org/id/ENSBTAT00000067297.3" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000064404.2", "url": "https://www.ensembl.org/id/ENSBTAP00000064404.2" } ] } }, { "isoform_ac": "A0AAA9SAD9-1", "url": "https://www.uniprot.org/uniprotkb/A0AAA9SAD9/entry", "sequence": { "sequence": "MICRLMFLCRRRFCSRPFLVGLVVAICLFYQTLTLWGTKKLAAAGPGAAPNTPTKTQASRCTKEFFLDKQCFLLSDIAQEIGKIEQSVETHFSSHGRRAVLYRPSSSSQRELQLHRSILTQHHYTVVISEERLGADPGLLEKGDLDSWDLLICLSSKTPGGKPCISKEDMCQLNLHQKVNMLPEIQHQLCRKEGLCQIIKRFPELRLLVSPSVCLNQSIQLKLRTSSHLLKTLKSQMWKPGDWRREQLNQTTALAPQETLLRAKDLSVILKAYVLVTSLTPLRAFIHSAGMVWNPPKKKRFTVKLQTFFETFLRASSPLQAFDTMREAISKLLLAAEVFSETSTLGPKIFQRCRLCFQLLTFDIGYGSVRSPVVLQVHEHLNFQDDDDMAFEDQNIEEFLLKDTFSFLLSNDSSLSIFSEIFQRLYRSAVVKGENYQKELNRCLSLEEINSIMTFIKELRSLGQFQLLFPSTTPGFQSLIGEFYGMTSPMGKPGSILTQYWSLLSVFEQFQLLNKKAEPHPLEWNSFTEDGNIKKPRVPFDAIENKKDKDAQCHIKQIFTHPRLELNPEFNPKIKDYYSEVPFDVVTLTIGAETSKSQCRVYLQERAGPSFANYSLGLGMNKISVLVVDKSPTQGETLTTYKLTIYREDRPSLPLFEDFTACGFVQDCGLLIQPEETCGLQPISSDYIEAISQPELKTCPSGDTKGQWIVPCLSCSDNRTCDWREITWQPHHCQYGVVTKPQLQQCLGGRKILFIGDSTNRGIMYYLIERLNETLEEWQKVHGTKFYHNVNGGKTLISYSYYPRFWMSPSLRPTFEKALEHLLQRSGPLENTSQTVLVVGGVQWLNSNHLQIIHKVLKREDLLNILVIIKTLGIGFHLPVDGVHFLTQNEVQNLWKKNLIILEDAKKYGYEVVDTFAITMGRHKEFLQGTCGCHFHEVIKSKLSKEDHFLKTKQSRNHIVGKYFSNQSKLQQRRQDSMTNVQSPFHVRGPINQVCSEILLSRICAPERTVEALQKD", "length": 1016, "header": "tr|A0AAA9SAD9-1|G3MWQ8_BOVIN Computationally mapped isoform of Cadherin like and PC-esterase domain containing 1 OS=Bos taurus OX=9913 GN=CPED1 PE=4 SV=1 CANONICAL=G3MWQ8-1" }, "locus": { "chromosome": "4", "start_pos": 85814158, "end_pos": 85492197, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000096704.2", "url": "https://www.ensembl.org/id/ENSBTAT00000096704.2" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000083056.1", "url": "https://www.ensembl.org/id/ENSBTAP00000083056.1" } ] } }, { "isoform_ac": "E1BF84-1", "url": "https://www.uniprot.org/uniprotkb/E1BF84/entry", "sequence": { "sequence": "MEELSAMSLSQSWVSRETLTLWGTKKLAAAGPGAAPNTPTKTQASRCTKEFFLDKQCFLLSDIAQEIGKIEQSVETHFSSHGRRAVLYRPSSSSQRELQLHRSILTQHHYTVVISEERLGADPGLLEKGDLDSWDLLICLSSKTPGGKPCISKEDMCQLNLHQKVNMLPEIQHQLCRKEGLCQIIKRFPELRLLVSPSVCLNQSIQLKLRTSSHLLKTLKSQMWKPGDWRREQLNQTTALAPQETLLRAKDLSVILKAYVLVTSLTPLRAFIHSAGMVWNPPKKKRFTVKLQTFFETFLRASSPLQAFDTMREAISKLLLAAEVFSETSTLGPKIFQRCRLCFQLLTFDIGYGSVRSPVVLQVHEHLNFQDDDDMAFEDQNIEEFLLKDTFSFLLSNDSSLSIFSEIFQRLYRSAVVKGENYQKELNRCLSLEEINSIMTFIKELRSLGQFQLLFPSTTPGFQSLIGEFYGMTSPMGKPGSILTQYWSLLSVFEQFQLLNKKAEPHPLEWNSFTEDGNIKKPRVPFDAIENKKDKDAQCHIKQIFTHPRLELNPEFNPKIKDYYSEVPFDVVTLTIGAETSKSQCRVYLQERAGPSFANYSLGLGMNKISVLVVDKSPTQGETLTTYKLTIYREDRPSLPLFEDFTACGFVQDCGLLIQPEETCGLQPISSDYIEAISQPELKTCPSGDTKGQWIVPCLSCSDNRTCDWREITWQPHHCQYGVVTKPQLQQCLGGRKILFIGDSTNRGIMYYLIERLNETLEEWQKVHGTKFYHNVNGGKTLISYSYYPRFWMSPSLRPTFEKALEHLLQRSGPLENTSQTVLVVGGVQWLNSNHLQIIHKVLKREDLLNILVIIKTLGIGFHLPVDGVHFLTQNEVQNLWKKNLIILEDAKKYGYEVVDTFAITMGRHKEFLQGTCGCHFHEVIKSKLSKEDHFLKTKQSRNHIVGKYFSNQSKLQQRRQDSMTNVQSPFHVRGPINQVCSEILLSRICAPERTVEALQKD", "length": 1002, "header": "tr|E1BF84-1|G3MWQ8_BOVIN Computationally mapped isoform of Cadherin like and PC-esterase domain containing 1 OS=Bos taurus OX=9913 GN=CPED1 PE=4 SV=4 CANONICAL=G3MWQ8-1" }, "locus": { "chromosome": "4", "start_pos": 85814158, "end_pos": 85490442, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000003820.8", "url": "https://www.ensembl.org/id/ENSBTAT00000003820.8" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000003820.7", "url": "https://www.ensembl.org/id/ENSBTAP00000003820.7" } ] } }, { "isoform_ac": "G3MWQ8-1", "url": "https://www.uniprot.org/uniprotkb/G3MWQ8/entry", "sequence": { "sequence": "MICRLMFLCRRRFCSRPFLVGLVVAICLFYQTLTLWGTKKLAAAGPGAAPNTPTKTQASRCTKEFFLDKQCFLLSDIAQEIGKIEQSVETHFSSHGRRAVLYRPSSSSQRELQLHRSILTQHHYTVVISEERLGADPGLLEKGDLDSWDLLICLSSKTPGGKPCISKEDMCQLNLHQKVNMLPEIQHQLCRKEGLCQIIKRFPELRLLVSPSVCLNQSIQLKLRTSSHLLKTLKSQMWKPGDWRREQLNQTTALAPQETLLRAKDLSVILKAYVLVTSLTPLRAFIHSAGMVWNPPKKKRFTVKLQTFFETFLRASSPLQAFDTMREAISKLLLAAEVFSETSTLGPKIFQRCRLCFQLLTFDIGYGSVRSPVVLQVHEHLNFQDDDDMAFEDQNIEEFLLKDTFSFLLSNDSSLSIFSEIFQRLYRSAVVKGENYQKELNRCLSLEEINSIMTFIKELRSLGQFQLLFPSTTPGFQSLIGEFYGMTSPMGKPGSILTQYWSLLSVFEQFQLLNKKAEPHPLEWNSFTEDGNIKKPRVPFDAIENKKAVVPQIMNETKEMHCHNDKDAQCHIKQIFTHPRLELNPEFNPKIKDYYSEVPFDVVTLTIGAETSKSQCRVYLQERAGPSFANYSLGLGMNKISVLVVDKSPTQGETLTTYKLTIYREDRPSLPLFEDFTACGFVQDCGLLIQPEETCGLQPISSDYIEAISQPELKTCPSGDTKGQWIVPCLSCSDNRTCDWREITWQPHHCQYGVVTKPQLQQCLGGRKILFIGDSTNRGIMYYLIERLNETLEEWQKVHGTKFYHNVNGGKTLISYSYYPRFWMSPSLRPTFEKALEHLLQRSGPLENTSQTVLVVGGVQWLNSNHLQIIHKVLKREDLLNILVIIKTLGIGFHLPVDGVHFLTQNEVQNLWKKNLIILEDAKKYGYEVVDTFAITMGRHKEFLQGTCGCHFHEVIKSKLSKEDHFLKTKQSRNHIVGKYFSNQSKLQQRRQDSMTNVQSPFHVRGPINQVCSEILLSRICAPERTVEALQKD", "length": 1033, "header": "tr|G3MWQ8-1|G3MWQ8_BOVIN Isoform 1 of Cadherin like and PC-esterase domain containing 1 OS=Bos taurus OX=9913 GN=CPED1 PE=4 SV=1 CANONICAL=G3MWQ8-1" }, "locus": { "chromosome": "4", "start_pos": 85814158, "end_pos": 85492197, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000063644.4", "url": "https://www.ensembl.org/id/ENSBTAT00000063644.4" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000053961.1", "url": "https://www.ensembl.org/id/ENSBTAP00000053961.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [ { "id": "bta:617867", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?bta:617867", "resource": "KEGG Pathway" } ], "orthologs": [ { "uniprot_canonical_ac": "A0A8I6AHU9-1", "protein_name": "Cadherin-like and PC-esterase domain containing 1", "gene_name": "Cped1", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MVCRPGFLCRRRFCPRPFLVGLVVAICLFYQTLTLRGTKKIAAEVSGTVPHTPSQTQGSRCEKDYPQDKRCFLLSANAQEIRKIEELIERHFGGRSRRAVLHRPPSSSGAELQTHQNLLAQHGYSVVTVEERLGGNPGLELLDQGGLNSWDLFICLPSREADGKPCIPREHMCRLSLHQRVNVLPEIQPQLCRKEGLCEIIRRFPELRLPVSSSVCLGQGTQSRLSVSSHLSKAEKPRIWKPWNWQREQLNQTTLVAPREAIFRAEELSVILKAYVLVTSLRPLRAFIHSTGTVWSPPKKKRFTVKLQMFFETFLRTSSPLQALDSLKEAISKLLLVAEVFSDSSTLGPKTFHRCRHCFQLMTFDIGYGDPGNPVVLQVHERLKFHDDENLHVEDQNTERILLRDTFDFLFSNASSLPVVSEMLQRPERAGASVDGKYQKELNQCLSLEEIHSIRTFVKELGNLGQFQLLFPSTVPGIQSLMGEFYDTATPGSVLSHYWSLLNVFEQFWLVNKKAQLHSLEWNSSTRNQTVEKPHRSLEAIQSKKAAVPQVLYEDKDKHCSDEEEAQCQIKKIVTYPRLELSPEFNAKIKDYYCEVPFDVLTVRIRAETSKCQCKVHLQEQTGPSFANYPLGLGMNRISMLVVDESRAEGDALTTYKLTIYREDRPSLPFFEDFTACGFVQDCDLLIHPEETCGLQPISADYIETISQPEIQSCQSGDTKGQWIVPCLTCSDNRTCDWREITWQPHNCQHDILSKPELQQCLQGRKILFIGDSTNRGMMYYLIERLNETLQEWQKLHGTKLYPSVNGGKTLISYSYYPQFWISPSLRPAFEKALERLLQRSQPLENTDQTVLVVGGVQWLNSNHLQIIHKVLKRENLQNILVIIKTLGIGFHLPVDGVHFLTQSEVRNLYKENLSILEAAKKYGYEVVDTFTITMGRHKEFLQGNCGCHFHEVVKSKFARPHHVIKMKRSKNHIVGKYFSSQSKLKQHNSAPNVHSPYHVRGPINQVCAEILLSRMCVSQRSARVP", "length": 1026 }, "evidence": [ { "id": "G3MWQ8", "url": "https://omabrowser.org/oma/group/G3MWQ8/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "A0A8V0X216-1", "protein_name": "Cadherin like and PC-esterase domain containing 1", "gene_name": "CPED1", "tax_id": 9031, "organism": "Gallus gallus", "sequence": { "sequence": "MVCGHGPRCRRLCRPRPFLLALVVAVCLFCQTLTPLMTNSFLSAVVNGISPNKQSKTRQGRYKEVSASDTHCFFPISDSHTLKKIEDTILQYFGSHTRRAILYAPPAHSKTERQLCQRMLAKHGYAVTVLENRRLVEDMRHEGPNHSSISPWDLLICLSSTRDDDTSCIQRDDLHQLELFQKVNLLPEIQYFLCSKEGLCQITKAFSDLQLSIATPECSSWHGLSRDSTASNIIHGSKSNVKTHIAHLQFLWSQTNGAQLNQVSASSEHRNILKAQDLSVIIKAYVLVTSLTPLRAFLHSAATVWHPPKKKHFSVKLQRFFEMFFKSSSPQQAFNNMKEAISKLLLITEVLSESSASGPGSFNQCSQCFQMLTFDIGFSTSIHPIVLQVHKHFDFQDEEESNLQDQTFKEVIFEDTFKFLLSNKSSSSSFIESLQNIYGSTVSKDGIFLKEDGHCFSLGEINSMITFVKEVKNLGQFELLYPSAAPKIQTLLRDLYHMVDPMRRLGSVLTVHWLLSSLLGQFQFMTKEAHTDLSVWRRKKSSRKSSPTAMKWLEPRNSSEENVIPKQKFHFRLRKNHEALRYSSKTKEIQCSHDKDTLSHIRQIFTSPQLDLNPQFNPKIREYYAEVPFDVVTVKIGAEPSNCQCQVHLDEVKGPSIANYPLGLGLNKIVVLVTDDSQPSPQVVSSYKIKIYREDRPSLPVFDDYMICGFVQDCGFQIHPEESCGLQPLSHEYLSAISQTVLKTCEAGDAKGQWIVPCLSCSDNRTCDWREIMWQPHGCQYSVLDKPELQQCVEGRKILFIGDSTNRGMMYYLIERVNETLQEWQKTHDVKCYDNINEGKTFISYSYYPQFWMTANQRPTFEKALEQLLQRSRPLENTDQTVLIVGGVQWLNSNHLQIIQKVLNRENLSNILVIIKSIGMGFHLPVDGIHSLSQAEVQNLWNENLVILETAKTYGYEVVDTFIITMGRYKEFLRGKCGCHFHEVVKSNPSEESPHITMTLSRHYTLGKYFSSQSKLSQLQDYASNSQSPYHVRGPINQVYSEILLNRLCTSKRGFVST", "length": 1058 }, "evidence": [ { "id": "G3MWQ8", "url": "https://omabrowser.org/oma/group/G3MWQ8/", "database": "OMA" } ], "glygen_name": "Chicken", "common_name": "Chicken" }, { "uniprot_canonical_ac": "A4D0V7-1", "protein_name": "Cadherin-like and PC-esterase domain-containing protein 1", "gene_name": "CPED1", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MVCRPVFPCRRRFCPRPFLVGLVVAICLFYQTLTLRGSRKLTAAAPGAVPHTSTETQASRCKKGFSQDKQCFLLSGNAQETRKVKESMETHFGSHGRRAILYRPPFYSKTELQLHQHILTQHGYTVVIAEERLNAGLGPGLLEQGDLGSWDLLICLSSKKAEGTPCISKEVMCQLGLHQKANRLPEIQQPLCRKEGLCQIVRRFPELQLPVSPSVCLDQGMQLKPSTSSHLLKTVKPRVWKPGDWSREQLNETTVLAPHETIFRAEDLSVILKAYVLVTSLTPLRAFIHSTGTVWNPPKKKRFTVKLQTFFETFLRASSPQQAFDIMKEAIGKLLLAAEVFSETSTLGPKTFHRCRFCFQLLTFDIGYGSFMYPVVLQVHEHLNFQDYDNMDFEDQNTEEFLLNDTFNFLFPNESSLSIFSEIFQRLYRSDVFKGENYQKELNQCLSLEEINSIMTFIKELGSLGQFQLLFPSTTPGIQSLMHEFYDVANPVGNPGSVLTQYWSLLNVFEQFQFMNKKTQPHPLEWNSFTEDKNIEKPQVPFDAIENKKAAVPQIKNENKEIHCSDDENTPCHIKQIFTHPHLELNPDFHPKIKDYYCEVPFDVVTVTIGVETPKCLCKVHLYEQAGPSFASYPLGLGMNKISIFVVDESPAHGETLITYKLTIYREDRPSLPLFEAFTACGFVQDCGLLIHPEETCGLQPISSDYIEAILQSELKRCPSGDMKGQWIVPCLSCSDNRTCDWREITWQPHNCQYGVLTKPQLQQCLGGRKILFIGDSTNRGIMYYLIERLNETLQEWQKVHGTKFYHNVNGGKTLISYSYYPQFWISPSLRPTFENALEHLLQRSRPLENTGQTVLVVGGVQWLNSNHLQIIHKVLKRENLLNILVIIKTLGIGFHLPVDGVHFLTQSEVQNLWKENLIILDTAKKHGYEVVDTFTITMGRYKEFLQGKCGCHFHEVVKSKLSKEYNFIKMKRSRNHIMGRYFSNQSKLQQGTVTNFRSPYHVRGPINQVCSEILLSRMCANKRTM", "length": 1026 }, "evidence": [ { "id": "G3MWQ8", "url": "https://omabrowser.org/oma/group/G3MWQ8/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" } ], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 1, "go_terms": [ { "name": "endoplasmic reticulum", "id": "GO:0005783", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005783", "evidence": [ { "database": "UniProtKB", "id": "G3MWQ8", "url": "https://www.uniprot.org/uniprotkb/G3MWQ8" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 216, "end_pos": 218, "annotation": "n_glycosylation_sequon" }, { "start_pos": 249, "end_pos": 251, "annotation": "n_glycosylation_sequon" }, { "start_pos": 411, "end_pos": 413, "annotation": "n_glycosylation_sequon" }, { "start_pos": 555, "end_pos": 557, "annotation": "n_glycosylation_sequon" }, { "start_pos": 630, "end_pos": 632, "annotation": "n_glycosylation_sequon" }, { "start_pos": 735, "end_pos": 737, "annotation": "n_glycosylation_sequon" }, { "start_pos": 789, "end_pos": 791, "annotation": "n_glycosylation_sequon" }, { "start_pos": 848, "end_pos": 850, "annotation": "n_glycosylation_sequon" }, { "start_pos": 983, "end_pos": 985, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [ { "pdb_id": "AF-G3MWQ8-F1", "pdb_chain": "global", "start_pos": 1, "end_pos": 1033, "overlap": "1.0", "method": "AlphaFold", "type": "alphafold", "resolution": -1.0, "url": "https://data.glygen.org/ln2downloads/pdb/current/AF-G3MWQ8-F1.pdb", "url_external": "https://alphafold.ebi.ac.uk/entry/G3MWQ8" } ], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "G3MWQ8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3MWQ8" }, { "id": "PF12733", "database": "Pfam", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF12733" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "Cadherin-like beta-sandwich-like", "eco_id": "ECO_0000259", "start_pos": 581, "end_pos": 665, "start_aa": "Leu", "end_aa": "Glu", "glycosite_overlap": [] }, { "evidence": [ { "id": "G3MWQ8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3MWQ8" }, { "id": "PF24536", "database": "Pfam", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF24536" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "NXPE C-terminal", "eco_id": "ECO_0000259", "start_pos": 745, "end_pos": 806, "start_aa": "Trp", "end_aa": "Asn", "glycosite_overlap": [] } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" }, { "name": "homologset.oma", "label": "OMA Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 216, "end_pos": 218 }, { "start_pos": 249, "end_pos": 251 }, { "start_pos": 411, "end_pos": 413 }, { "start_pos": 555, "end_pos": 557 }, { "start_pos": 630, "end_pos": 632 }, { "start_pos": 735, "end_pos": 737 }, { "start_pos": 789, "end_pos": 791 }, { "start_pos": 848, "end_pos": 850 }, { "start_pos": 983, "end_pos": 985 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", 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"length": 1294, "header": "tr|E1BFY7-1|G3N021_BOVIN Computationally mapped isoform of Collagen alpha-1(XX) chain OS=Bos taurus OX=9913 GN=COL20A1 PE=3 SV=4 CANONICAL=G3N021-1" }, "locus": { "chromosome": "13", "start_pos": 54281679, "end_pos": 54262438, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000006018.6", "url": "https://www.ensembl.org/id/ENSBTAT00000006018.6" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000006018.6", "url": "https://www.ensembl.org/id/ENSBTAP00000006018.6" } ] } }, { "isoform_ac": "G3MZQ1-1", "url": "https://www.uniprot.org/uniprotkb/G3MZQ1/entry", "sequence": { "sequence": 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"length": 1183, "header": "tr|G3MZQ1-1|G3MZQ1_BOVIN Computationally mapped isoform of Collagen alpha-1(XX) chain OS=Bos taurus OX=9913 GN=COL20A1 PE=4 SV=3 CANONICAL=G3N021-1" }, "locus": { "chromosome": "13", "start_pos": 54281686, "end_pos": 54264218, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000065814.3", "url": "https://www.ensembl.org/id/ENSBTAT00000065814.3" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000055054.3", "url": "https://www.ensembl.org/id/ENSBTAP00000055054.3" } ] } }, { "isoform_ac": "G3N021-1", "url": "https://www.uniprot.org/uniprotkb/G3N021/entry", "sequence": { "sequence": "TMAAGSLQLCLHFLTACPASSASGRLRLAVLPEDRLQMKWRESEGSSLGYLVQVKPRAGDPEQEVMLTTKTPKATVGGLSPSKGYTLQIFELTGSGNILLARREFVIEDLKSNSVSRSSQRPLGATLEPTPSLVGSPDLEPPGALAPSQDPPTLGGAKSGDGMCLGTGGREGPAQPTPDLEGPNHARTSAGGRGKPGRPQFRCTPPMPVDMIFLVDGSWSIGHSHFQQVKDFLASVIEPFEIGPGKVQVGLTQYSGAPQTEWDLNAFGTKEEVLNAVHNLHYRGGNTFTGLALTHVLEQNLKPRAGLRPEAAKLVILVTDGKSQDDAHTAGHVLKGLGVDIFAVGVKNADETELRLLASQPLDITVHNVQDFPQLSTLSGLLSRLICQKVQGRSPRGSPATPALDPPPAPTRLVLTQVTSSSVLLSWSPAPQPPLKYLIVWRPSKGGTPREVVVEGPTSSAQLHNLTSSTEYLVSVFPLYKAGVGEGLQGLATTAPLPPPQALTLAAVTPKTVRLTWQPSAEATQYLVRWSPASPKGEEERREVRVGRPEVLLDGLAPGRDYDVWVQSLRGAEISEAQGIRARTPALTTPRHLSFSDVSHDSARVSWEGTARPVRLFRVSYISGKGGHSGQTEVPGNATSAILGPLSSSTTYMVRVTCLYPGGSSSTLTSRLTTRKVPSPSQLSVTELPGDEVRLEWAAAAVSGVLVYQITWMPLGEGKAREISVPGNLGTAILPGLGRHSEYEITILAYYRDGARSDPVSLRYTPVSRSPPSNLALASESPDSLRVSWTPPSSHVLHYRLSYALASGSGPEKSISIPGPGSHVTIPDLLAATKYRVLVSAIYGAGESVAVSATGRTAACPALHLDGSLPGFDLMAAFGLVEKEYASIRGVAMEPSAFGPTRTFTLFKDSQLTRRASDIHLATLPPEHTVVFLLRLLPETPREAFALWQVASEDFQPILGVLLDAGRKSLTYFNRDPRATLQEVTFDLPEVRRIFFGSFHKVHVAVGRARVRLYVDCRKVAERPIGEAGGLPAAGFVMLGRLAKARGPRSSSASFQLQVLQLVCNDSWAEEDRCCELPASKEGESCPAFPSACACSSQTPGPPGPQGPPVSPAVPPWGNQGLRPHLPCLQGEPGPPGQMGPEGPGGQQGSPGTQGRTIQGPVGPPGVKGEKGDHGHPGLQGHPGLQGTPGKIGIQGPKVGEKPAEVGPLLSGDSWVSGQLWGPGTSPFPPSQGLPGPKGERGEKGEPQSLATIYQLVGQACESAIQTHVLKLHACTHESTRPPMPILEAPRALGTSNKARLPGEGGHGGPHPGDRGTGGGVFSSPGAVCCEWSGHG", 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"GlyGen", "url": "https://data.glygen.org/" } ], "filter_code": "000000000000000010000.00000000001000.0.01000" }, { "glytoucan_ac": "", "type": "O-linked", "subtype": "other", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 177, "start_aa": "Thr", "end_pos": 177, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr177", "evidence": [ { "id": "", "database": "GlyGen", "url": "https://data.glygen.org/" } ], "filter_code": "000000000000000010000.00000000001000.0.01000" }, { "glytoucan_ac": "", "type": "O-linked", "subtype": "other", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 401, "start_aa": "Thr", "end_pos": 401, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr401", "evidence": [ { "id": "", "database": "GlyGen", "url": "https://data.glygen.org/" } ], "filter_code": "000000000000000010000.00000000001000.0.01000" }, { "glytoucan_ac": "", "type": "O-linked", "subtype": "other", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 458, "start_aa": "Thr", "end_pos": 458, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr458", "evidence": [ { "id": "", "database": "GlyGen", "url": "https://data.glygen.org/" } ], "filter_code": "000000000000000010000.00000000001000.0.01000" } ], "phosphorylation": [], "glycation": [], "keywords": [ "glycoprotein", "glycoprotein_predicted" ], "publication": [], "pathway": [ { "id": "R-BTA-1650814", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-BTA-1650814", "resource": "Reactome", "description": "Collagen biosynthesis and modifying enzymes" }, { "id": "R-BTA-8948216", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-BTA-8948216", "resource": "Reactome", "description": "Collagen chain trimerization" } ], "orthologs": [], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 1, "go_terms": [ { "name": "extracellular region", "id": "GO:0005576", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005576", "evidence": [ { "database": "UniProtKB", "id": "G3N021", "url": "https://www.uniprot.org/uniprotkb/G3N021" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 1065, "end_pos": 1067, "annotation": "n_glycosylation_sequon" }, { "start_pos": 465, "end_pos": 467, "annotation": "n_glycosylation_sequon" }, { "start_pos": 637, "end_pos": 639, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], 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"categories": [] }, { "id": "ENSBTAG00000005330", "url": "https://bgee.org/?page=gene&gene_id=ENSBTAG00000005330", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "504775", "url": "https://www.ncbi.nlm.nih.gov/gene/504775", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR028196", "url": "https://www.ebi.ac.uk/interpro/entry/IPR028196", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR059487", "url": "https://www.ebi.ac.uk/interpro/entry/IPR059487", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "bta:504775", "url": "https://www.genome.jp/dbget-bin/www_bget?bta:504775", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "WRSAFQS", "url": "https://omabrowser.org/oma/group/WRSAFQS/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "E1BI48", "url": "https://www.orthodb.org/?gene=E1BI48", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "G3N276", "url": "https://www.orthodb.org/?gene=G3N276", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR36463", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR36463", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR36463:SF1", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR36463:SF1", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF15200", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF15200", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "NP_001291643", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001291643", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "E1BI48", "url": "https://www.uniprot.org/uniprotkb/E1BI48", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "E1BI48-1", "url": "https://www.uniprot.org/uniprotkb/E1BI48-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "G3N276", "url": "https://www.uniprot.org/uniprotkb/G3N276", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "G3N276-1", "url": "https://www.uniprot.org/uniprotkb/G3N276-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MKIPVLPAVVLLSVLALHSAQGAALPSSEEETTIGNYEAGPEAFKKDEFLNWHALFESIKQKLPFLNWDAFPKLKGLRSATPDAQ", "length": 85, "header": "tr|G3N276-1|G3N276_BOVIN Isoform 1 of Keratinocyte differentiation associated protein OS=Bos taurus OX=9913 GN=KRTDAP PE=4 SV=2 CANONICAL=G3N276-1" }, "isoforms": [ { "isoform_ac": "E1BI48-1", "url": "https://www.uniprot.org/uniprotkb/E1BI48/entry", "sequence": { "sequence": "MKIPVLPAVVLLSVLALHSAQGAALPSSEEETTIGNYEAGPEAFNAQFLNIDKLRSAFKKDEFLNWHALFESIKQKLPFLNWDAFPKLKGLRSATPDAQ", "length": 99, "header": "tr|E1BI48-1|G3N276_BOVIN Computationally mapped isoform of Keratinocyte differentiation associated protein OS=Bos taurus OX=9913 GN=KRTDAP PE=4 SV=1 CANONICAL=G3N276-1" }, "locus": { "chromosome": "18", "start_pos": 46156041, "end_pos": 46152724, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000044506.3", "url": "https://www.ensembl.org/id/ENSBTAT00000044506.3" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000041998.2", "url": "https://www.ensembl.org/id/ENSBTAP00000041998.2" } ] } }, { "isoform_ac": "G3N276-1", "url": "https://www.uniprot.org/uniprotkb/G3N276/entry", "sequence": { "sequence": "MKIPVLPAVVLLSVLALHSAQGAALPSSEEETTIGNYEAGPEAFKKDEFLNWHALFESIKQKLPFLNWDAFPKLKGLRSATPDAQ", "length": 85, "header": "tr|G3N276-1|G3N276_BOVIN Isoform 1 of Keratinocyte differentiation associated protein OS=Bos taurus OX=9913 GN=KRTDAP PE=4 SV=2 CANONICAL=G3N276-1" }, "locus": { "chromosome": "18", "start_pos": 46156041, "end_pos": 46152724, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000062974.2", "url": "https://www.ensembl.org/id/ENSBTAT00000062974.2" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000055985.2", "url": "https://www.ensembl.org/id/ENSBTAP00000055985.2" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [ { "id": "bta:504775", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?bta:504775", "resource": "KEGG Pathway" } ], "orthologs": [ { "uniprot_canonical_ac": "A0A4X1TM18-1", "protein_name": "Keratinocyte differentiation associated protein", "gene_name": "KRTDAP", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MRIPVLPAVVLLSVLALHSAQGAALGGAEEETTVDNYEARPEVLKPEEFLNWHALFETIKRKLPFLNWDAFPKLKGLRSATPDAQ", "length": 85 }, "evidence": [ { "id": "G3N276", "url": "https://omabrowser.org/oma/group/G3N276/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "P60985-1", "protein_name": "Keratinocyte differentiation-associated protein", "gene_name": "KRTDAP", "tax_id": 9606, "organism": "Homo 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"evidence": [ { "database": "UniProtKB", "id": "G3N276", "url": "https://www.uniprot.org/uniprotkb/G3N276" } ], "pmid": "" }, { "name": "lamellar body", "id": "GO:0042599", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0042599", "evidence": [ { "database": "UniProtKB", "id": "G3N276", "url": "https://www.uniprot.org/uniprotkb/G3N276" } ], "pmid": "" }, { "name": "extracellular region", "id": "GO:0005576", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005576", "evidence": [ { "database": "UniProtKB", "id": "G3N276", "url": "https://www.uniprot.org/uniprotkb/G3N276" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 1, "go_terms": [ { "name": "epidermis development", "id": "GO:0008544", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008544", "evidence": [ { "database": "UniProtKB", "id": "G3N276", "url": "https://www.uniprot.org/uniprotkb/G3N276" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [], "ptm_annotation": [], "interactions": [], "reactions": 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"tr|G3N060-1|G3N060_BOVIN Isoform 1 of Family with sequence similarity 98 member C OS=Bos taurus OX=9913 GN=FAM98C PE=3 SV=3 CANONICAL=G3N060-1" }, "isoforms": [ { "isoform_ac": "E1BJ38-1", "url": "https://www.uniprot.org/uniprotkb/E1BJ38/entry", "sequence": { "sequence": "MEGAEAEEQEWAAVAQDLLALGYEGCPGAASPGTSCPDFRALCARLAAELATLGALEREREEGTEALSAGDDPGAEEEFLRQLAGLLRELHCPDRELCGGDCAASLREPDARLRLLRFLCSEVQAARLLRLRSRLDPNPEPSCGEEAEEGSGMVQELILTLQALGLPRPTRGTPACQLLQDLHAKEALASLSQSLRDQYGCRRSLLLKRLDLTTSAFHWSDRAEVLMGSVPDRGGRPNELEAPMPSWQSRREDGGGRKAGRQCWGRKKKKK", "length": 271, "header": "tr|E1BJ38-1|G3N060_BOVIN Computationally mapped isoform of Family with sequence similarity 98 member C OS=Bos taurus OX=9913 GN=FAM98C PE=3 SV=3 CANONICAL=G3N060-1" }, "locus": { "chromosome": "18", "start_pos": 48213998, "end_pos": 48210246, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000054188.4", "url": "https://www.ensembl.org/id/ENSBTAT00000054188.4" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000050888.3", "url": "https://www.ensembl.org/id/ENSBTAP00000050888.3" } ] } }, { "isoform_ac": "G3N060-1", "url": "https://www.uniprot.org/uniprotkb/G3N060/entry", "sequence": { "sequence": "MEGAEAEEQEWAAVAQDLLALGYEGCPGAASPGTSCPDFRALCARLAAELATLGALEREREEGTEALSAGDDPGAEEEFLRQLAGLLRELHCPDRELCGGDCAASLREPDARLRLLRFLCSEVQAARLLRLRSRLDPNPEPSCGEEAEEGSGMVQELILTLQALGLPRPTRGTPACQLLQDLHAKISALLPSLPPESLQPLLNHPLDAPRWVRLCMAEALASLSQSLRDQYGCRRSLLLKRLDLTTSAFHWSDRAEAQGEAMKAVLIPIREALTSESDISIAHVLAARADLSRLVPATSKTARQGTCCAINKVLMGSVPDRGGRPNELEAPMPSWQSRREDGGGRKAGRQCWGRKKKKK", "length": 359, "header": "tr|G3N060-1|G3N060_BOVIN Isoform 1 of Family with sequence similarity 98 member C OS=Bos taurus OX=9913 GN=FAM98C PE=3 SV=3 CANONICAL=G3N060-1" }, "locus": { "chromosome": "18", "start_pos": 48213998, "end_pos": 48210246, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000064932.4", "url": "https://www.ensembl.org/id/ENSBTAT00000064932.4" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000055216.3", "url": "https://www.ensembl.org/id/ENSBTAP00000055216.3" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [], "orthologs": [], "go_annotation": {}, "pro_annotation": [], "site_annotation": [], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [ { "pdb_id": "AF-G3N060-F1", "pdb_chain": "global", "start_pos": 1, "end_pos": 359, "overlap": "1.0", "method": "AlphaFold", "type": "alphafold", "resolution": -1.0, "url": "https://data.glygen.org/ln2downloads/pdb/current/AF-G3N060-F1.pdb", "url_external": "https://alphafold.ebi.ac.uk/entry/G3N060" } ], "lectin_list": [], "domain_list": [], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" } ], "sequence_features": { "n_linked_sites": [], 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"o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ], "tool_support": { "graph_view": "yes" } }, { "uniprot_canonical_ac": "G3MZG3-1", "uniprot_ac": "G3MZG3", "uniprot_id": "G3MZG3_BOVIN", "mass": { "chemical_mass": 155438.0, "monoisotopic_mass": 155438.0 }, "refseq": { "ac": "XP_010801349", "name": "regulation of nuclear pre-mRNA domain-containing protein 2 isoform X1", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_010801349" }, "gene_names": [ { "name": "RPRD2", "type": "recommended", "evidence": [ { "id": "G3MZG3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3MZG3" } ] }, { "name": "RPRD2", "type": "synonym", "evidence": [ { "id": "XP_010801349", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_010801349" } ] } ], "protein_names": [ { "name": "Regulation of nuclear pre-mRNA domain-containing protein 2", "type": "recommended", "evidence": [ { "id": "G3MZG3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3MZG3/entry#names_and_taxonomy" } ] }, { "name": "regulation of nuclear pre-mRNA domain-containing protein 2 isoform X1", "type": "synonym", "evidence": [ { "id": "XP_010801349", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_010801349" } ] } ], "function": [], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Bos taurus", "taxid": 9913, "evidence": [ { "database": "UniProtKB", "id": "G3MZG3", "url": "https://www.uniprot.org/uniprotkb/G3MZG3" } ], "common_name": "Bovine", "glygen_name": "Bovine", "reference_species": "Bos taurus [9913]" } ], "gene": [ { "name": "RPRD2", "url": "https://www.uniprot.org/uniprotkb/G3MZG3", "locus": { "chromosome": "3", "start_pos": 20203227, "end_pos": 20302218, "strand": "+", "evidence": [ { "database": "Ensembl Gene", "id": "ENSBTAG00000014984", "url": "https://www.ensembl.org/id/ENSBTAG00000014984" } ] } } ], "crossref": [ { "id": "ENSBTAG00000014984", "url": "https://bgee.org/?page=gene&gene_id=ENSBTAG00000014984", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "cd17001", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd17001", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "614766", "url": "https://www.ncbi.nlm.nih.gov/gene/614766", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR006569", "url": "https://www.ebi.ac.uk/interpro/entry/IPR006569", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR008942", "url": "https://www.ebi.ac.uk/interpro/entry/IPR008942", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR047885", "url": "https://www.ebi.ac.uk/interpro/entry/IPR047885", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "NYSHRAQ", "url": "https://omabrowser.org/oma/group/NYSHRAQ/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "E1BK49", "url": "https://www.orthodb.org/?gene=E1BK49", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "G3MX56", "url": "https://www.orthodb.org/?gene=G3MX56", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "G3MZG3", "url": "https://www.orthodb.org/?gene=G3MZG3", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR12460", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR12460", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR12460:SF40", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR12460:SF40", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF04818", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF04818", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "R-BTA-6807505", "url": "https://www.reactome.org/PathwayBrowser/#R-BTA-6807505", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "XP_010801349", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_010801349", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0AAA9S4T9", "url": "https://www.uniprot.org/uniprotkb/A0AAA9S4T9", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0AAA9S4T9-1", "url": "https://www.uniprot.org/uniprotkb/A0AAA9S4T9-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0AAA9SRJ2", "url": "https://www.uniprot.org/uniprotkb/A0AAA9SRJ2", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0AAA9SRJ2-1", "url": "https://www.uniprot.org/uniprotkb/A0AAA9SRJ2-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "E1BK49", "url": "https://www.uniprot.org/uniprotkb/E1BK49", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "E1BK49-1", "url": "https://www.uniprot.org/uniprotkb/E1BK49-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "G3MX56", "url": "https://www.uniprot.org/uniprotkb/G3MX56", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "G3MX56-1", "url": "https://www.uniprot.org/uniprotkb/G3MX56-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "G3MZG3", "url": "https://www.uniprot.org/uniprotkb/G3MZG3", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "G3MZG3-1", "url": "https://www.uniprot.org/uniprotkb/G3MZG3-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MAAGGGGGGSKASSSSASSAGALESSLDRKFQSVTNTMESIQGLSSWCIENKKHHTTIVYHWMKWLRRSAYPHRLNLFYLANDVIQNCKRKNAIIFRESFADVLPEAAALVKDPSVSKSIERIFKIWEDRNVYPEEMIMALREALSTTFKTQKQLKENLNKQPNKQWKKSQTSTNPKAALKSKIVAEFRSQALIEELLLYKRSEDQIELKEKQLSTMRVDVCSTETLKCLKDKTGGKKFSKEFEEASAKLEEFVNGLDKQVKNGPSLTEALENAGIFYEAQYKEVKVVANAYKTFANRVNNLKKKLDQLKSTLPDPEESPVPSPSVDAPSPTGSESPFQGMGGEESQSPNAESEKSATPEPATDNRDVEDMDLSDVEDDGSKIIAVEDRKEKPVEKSTVSTAVPTKPTESISKASSCTPAPVTMTATPPLPKPVNTSLLSPTPALALPNLANVDLAKISSILSSLTSVMKNTGVSPASRPSPGTPTSPSSLTSGLKTPAPATTTSHNPLANILSKVEITPESILSALSKTQTQSAPALQGLSSLLQSVTGNPVPSSEATPQSTSASPANTTVSSIKGRNLPSNTQSFIPKSFNYSPNSSTSEVSSTSASKASIGQSPGLPSTTFKLPSNTLGFTGNHSASPAAPPTEVAMCQSSEASKPKLESESTSPSLEMKIHNFLKGNPGFSGLNLNIPILSSLGSSAPAESHPSDFQRGPTSTSVDNIDGTPVRDERSGTPTQDEMMDKPTSSSVDTMSLLSKIISPGSSTPSSTRSPPPGREESFPRELSSSVSTFRPFGLGSDSPYKQPSDGMERPSSLMDSSQEKFYPDTSFQEDEDYRDFEYSGPPPSAMMNLEKKPAKSILKSSKLSDTTEYQPILSSYSHRGQEFGVKSAFPASVRALLDSSENCGRLSSPPGLFSAFGVRGNEAGSDRSPSPSKNDSFFTPDSNHNSLSQSATGHLTLPQKQYPDSPHPVPHRSLFSPQNTLAAPTGHPPTSGVEKVLASTISTTSTIEFKNMLKNASRKPSDDKHFGQAPNKGTSSDGVSLSNLAQLSLTAADQQQQEEHYRIETRVSSSCLDLPDSTEEKGAPIETLGYHNASSRRMSGEPIQTVESIRVPGKGNRGHGREASRVGWFDLSTSGGSFDNGPSSASELASLGGGGSGGLTGFKTAPYKERAPQFQESVGSFRSNSFNSTFEHHLPPSPLDHGTPFQREPVGPSSAPPAPPKDHGGIFSRDAPTHLPSVDLSNPFAKEAALTHAAPPPGEHGGVPFPTPPPPPPPGEHSSSGGSGVPFSAPPPPPPPGDHSGVVPFPTPPLAEHGVAGAVAVFPKDHSSLLQGTLADHFGVLPGPRDHGGPTQRDLNGPGLSRVRESLSLPSHSLEHLGPAHGGGGGGGSNSSSGPPLGPSHRDAINRSGMILRSPRPDFRPREPFLSRDPFHSLKRPRPPFARGPPFFAPKRPFFPPRY", "length": 1461, "header": "tr|G3MZG3-1|G3MZG3_BOVIN Isoform 1 of Regulation of nuclear pre-mRNA domain-containing protein 2 OS=Bos taurus OX=9913 GN=RPRD2 PE=4 SV=3 CANONICAL=G3MZG3-1" }, "isoforms": [ { "isoform_ac": "A0AAA9S4T9-1", "url": "https://www.uniprot.org/uniprotkb/A0AAA9S4T9/entry", "sequence": { "sequence": "MAAGGGGGGSKASSSSASSAGALESSLDRKFQSVTNTMESIQGLSSWCIENKKHHTTIVYHWMKWLRRSAYPHRLNLFYLANDVIQNCKRKNAIIFRESFADVLPEAAALVKDPSVSKSIERIFKIWEDRNVYPEEMIMALREALSTTFKTQKQLKENLNKQPNKQWKKSQTSTNPKAALKSKIVAEFRSQALIEELLLYKRSEDQIELKEKQLSTMRVDVCSTETLKCLKDKTGGKKFSKEFEEASAKLEEFVNGLDKQVKNGPSLTEALENAGIFYEAQYKEVKVVANAYKTFANRVNNLKKKLDQLKSTLPDPEESPVPSPSVDAPSPTGSESPFQGMGGEESQSPNAESEKSATPEPATDNRDVEDMDLSDVEDDGSKIIVEDRKEKPVEKSTVSTAVPTKPTESISKASSCTPAPVTMTATPPLPKPVNTSLLSPTPALALPNLANVDLAKISSILSSLTSVMKNTGVSPASRPSPGTPTSPSSLTSGLKTPAPATTTSHNPLANILSKVEITPESILSALSKTQTQSAPALQGLSSLLQSVTGNPVPSSEATPQSTSASPANTTVSSIKGRNLPSNTQSFIPKSFNYSPNSSTSEVSSTSASKASIGQSPGLPSTTFKLPSNTLGFTGNHSASPAAPPTEVAMCQSSEASKPKLESESTSPSLEMKIHNFLKGNPGFSGLNLNIPILSSLGSSAPAESHPSDFQRGPTSTSVDNIDGTPVRDERSGTPTQDEMMDKPTSSSVDTMSLLSKIISPGSSTPSSTRSPPPGREESFPRELSSSVSTFRPFGLGSDSPYKQPSDGMERPSSLMDSSQEKFYPDTSFQEDEDYRDFEYSGPPPSAMMNLEKKPAKSILKSSKLSDTTEYQPILSSYSHRGQEFGVKSAFPASVRALLDSSENCGRLSSPPGLFSAFGVRGNEAGSDRSPSPSKNDSFFTPDSNHNSLSQSATGHLTLPQKQYPDSPHPVPHRSLFSPQNTLAAPTGHPPTSGVEKVLASTISTTSTIEFKNMLKNASRKPSDDKHFGQAPNKGTSSDGVSLSNLAQLSLTAADQQQQEEHYRIETRVSSSCLDLPDSTEEKGAPIETLGYHNASSRRMSGEPIQTVESIRVPGKGNRGHGREASRVGWFDLSTSGGSFDNGPSSASELASLGGGGSGGLTGFKTAPYKERAPQFQESVGSFRSNSFNSTFEHHLPPSPLDHGTPFQREPVGPSSAPPAPPKDHGGIFSRDAPTHLPSVDLSNPFAKEAALTHAAPPPGEHGGVPFPTPPPPPPPGEHSSSGGSGVPFSAPPPPPPPGDHSGVVPFPTPPLAEHGVAGAVAVFPKDHSSLLQGTLADHFGVLPGPRDHGGPTQRDLNGPGLSRVRESLSLPSHSLEHLGPAHGGGGGGGSNSSSGPPLGPSHRDAINRSGMILRSPRPDFRPREPFLSRDPFHSLKRPRPPFARGPPFFAPKRPFFPPRMEIRICM", "length": 1466, "header": "tr|A0AAA9S4T9-1|G3MZG3_BOVIN Computationally mapped isoform of Regulation of nuclear pre-mRNA domain-containing protein 2 OS=Bos taurus OX=9913 GN=RPRD2 PE=4 SV=1 CANONICAL=G3MZG3-1" }, "locus": { "chromosome": "3", "start_pos": 20302019, "end_pos": 20208904, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000113373.1", "url": "https://www.ensembl.org/id/ENSBTAT00000113373.1" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000080950.1", "url": "https://www.ensembl.org/id/ENSBTAP00000080950.1" } ] } }, { "isoform_ac": "A0AAA9SRJ2-1", "url": "https://www.uniprot.org/uniprotkb/A0AAA9SRJ2/entry", "sequence": { "sequence": "MAAGGGGGGSKASSSSASSAGALESSLDRKFQSVTNTMESIQGLSSWCIENKKHHTTIVYHWMKWLRRSAYPHRLNLFYLANDVIQNCKRKNAIIFRESFADVLPEAAALVKDPSVSKSIERIFKIWEDRNVYPEEMIMALREALTSTNPKAALKSKIVAEFRSQALIEELLLYKRSEDQIELKEKQLSTMRVDVCSTETLKCLKDKTGGKKFSKEFEEASAKLEEFVNGLDKQVKNGPSLTEALENAGIFYEAQYKEVKVVANAYKTFANRVNNLKKKLDQLKSTLPDPEESPVPSPSVDAPSPTGSESPFQGMGGEESQSPNAESEKSATPEPATDNRDVEDMDLSDVEDDGSKIIVEDRKEKPVEKSTVSTAVPTKPTESISKASSCTPAPVTMTATPPLPKPVNTSLLSPTPALALPNLANVDLAKISSILSSLTSVMKNTGVSPASRPSPGTPTSPSSLTSGLKTPAPATTTSHNPLANILSKVEITPESILSALSKTQTQSAPALQGLSSLLQSVTGNPVPSSEATPQSTSASPANTTVSSIKGRNLPSNTQSFIPKSFNYSPNSSTSEVSSTSASKASIGQSPGLPSTTFKLPSNTLGFTGNHSASPAAPPTEVAMCQSSEASKPKLESESTSPSLEMKIHNFLKGNPGFSGLNLNIPILSSLGSSAPAESHPSDFQRGPTSTSVDNIDGTPVRDERSGTPTQDEMMDKPTSSSVDTMSLLSKIISPGSSTPSSTRSPPPGREESFPRELSSSVSTFRPFGLGSDSPYKQPSDGMERPSSLMDSSQEKFYPDTSFQEDEDYRDFEYSGPPPSAMMNLEKKPAKSILKSSKLSDTTEYQPILSSYSHRGQEFGVKSAFPASVRALLDSSENCGRLSSPPGLFSAFGVRGNEAGSDRSPSPSKNDSFFTPDSNHNSLSQSATGHLTLPQKQYPDSPHPVPHRSLFSPQNTLAAPTGHPPTSGVEKVLASTISTTSTIEFKNMLKNASRKPSDDKHFGQAPNKGTSSDGVSLSNLAQLSLTAADQQQQEEHYRIETRVSSSCLDLPDSTEEKGAPIETLGYHNASSRRMSGEPIQTVESIRVPGKGNRGHGREASRVGWFDLSTSGGSFDNGPSSASELASLGGGGSGGLTGFKTAPYKERAPQFQESVGSFRSNSFNSTFEHHLPPSPLDHGTPFQREPVGPSSAPPAPPKDHGGIFSRDAPTHLPSVDLSNPFAKEAALTHAAPPPGEHGGVPFPTPPPPPPPGEHSSSGGSGVPFSAPPPPPPPGDHSGVVPFPTPPLAEHGVAGAVAVFPKDHSSLLQGTLADHFGVLPGPRDHGGPTQRDLNGPGLSRVRESLSLPSHSLEHLGPAHGGGGGGGSNSSSGPPLGPSHRDAINRSGMILRSPRPDFRPREPFLSRDPFHSLKRPRPPFARGPPFFAPKRPFFPPRY", "length": 1434, "header": "tr|A0AAA9SRJ2-1|G3MZG3_BOVIN Computationally mapped isoform of Regulation of nuclear pre-mRNA domain-containing protein 2 OS=Bos taurus OX=9913 GN=RPRD2 PE=4 SV=1 CANONICAL=G3MZG3-1" }, "locus": { "chromosome": "3", "start_pos": 20302019, "end_pos": 20211415, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000126799.1", "url": "https://www.ensembl.org/id/ENSBTAT00000126799.1" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000088971.1", "url": "https://www.ensembl.org/id/ENSBTAP00000088971.1" } ] } }, { "isoform_ac": "E1BK49-1", "url": "https://www.uniprot.org/uniprotkb/E1BK49/entry", "sequence": { "sequence": "MAAGGGGGGSKASSSSASSAGALESSLDRKFQSVTNTMESIQGLSSWCIENKKHHTTIVYHWMKWLRRSAYPHRLNLFYLANDVIQNCKRKNAIIFRESFADVLPEAAALVKDPSVSKSIERIFKIWEDRNVYPEEMIMALREALSTTFKTQKQLKENLNKQPNKQWKKSQTSTNPKAALKSKIVAEFRSQALIEELLLYKRSEDQIELKEKQLSTMRVDVCSTETLKCLKDKTGGKKFSKEFEEASAKLEEFVNGLDKQVKNGPSLTEALENAGIFYEAQYKEVKVVANAYKTFANRVNNLKKKLDQLKSTLPDPEESPVPSPSVDAPSPTGSESPFQGMGGEESQSPNAESEKSATPEPATDNRDVEDMDLSDVEDDGSKIIVEDRKEKPVEKSTVSTAVPTKPTESISKASSCTPAPVTMTATPPLPKPVNTSLLSPTPALALPNLANVDLAKISSILSSLTSVMKNTGVSPASRPSPGTPTSPSSLTSGLKTPAPATTTSHNPLANILSKVEITPESILSALSKTQTQSAPALQGLSSLLQSVTGNPVPSSEATPQSTSASPANTTVSSIKGRNLPSNTQSFIPKSFNYSPNSSTSEVSSTSASKASIGQSPGLPSTTFKLPSNTLGFTGNHSASPAAPPTEVAMCQSSEASKPKLESESTSPSLEMKIHNFLKGNPGFSGLNLNIPILSSLGSSAPAESHPSDFQRGPTSTSVDNIDGTPVRDERSGTPTQDEMMDKPTSSSVDTMSLLSKIISPGSSTPSSTRSPPPGREESFPRELSSSVSTFRPFGLGSDSPYKQPSDGMERPSSLMDSSQEKFYPDTSFQEDEDYRDFEYSGPPPSAMMNLEKKPAKSILKSSKLSDTTEYQPILSSYSHRGQEFGVKSAFPASVRALLDSSENCGRLSSPPGLFSAFGVRGNEAGSDRSPSPSKNDSFFTPDSNHNSLSQSATGHLTLPQKQYPDSPHPVPHRSLFSPQNTLAAPTGHPPTSGVEKVLASTISTTSTIEFKNMLKNASRKPSDDKHFGQAPNKGTSSDGVSLSNLAQLSLTAADQQQQEEHYRIETRVSSSCLDLPDSTEEKGAPIETLGYHNASSRRMSGEPIQTVESIRVPGKGNRGHGREASRVGWFDLSTSGGSFDNGPSSASELASLGGGGSGGLTGFKTAPYKERAPQFQESVGSFRSNSFNSTFEHHLPPSPLDHGTPFQREPVGPSSAPPAPPKDHGGIFSRDAPTHLPSVDLSNPFAKEAALTHAAPPPGEHGGVPFPTPPPPPPPGEHSSSGGSGVPFSAPPPPPPPGDHSGVVPFPTPPLAEHGVAGAVAVFPKDHSSLLQGTLADHFGVLPGPRDHGGPTQRDLNGPGLSRVRESLSLPSHSLEHLGPAHGGGGGGGSNSSSGPPLGPSHRDAINRSGMILRSPRPDFRPREPFLSRDPFHSLKRPRPPFARGPPFFAPKRPFFPPRVSNIPEDGAKIRSGACDSDQLLPPQTEPLET", "length": 1490, "header": "tr|E1BK49-1|G3MZG3_BOVIN Computationally mapped isoform of Regulation of nuclear pre-mRNA domain-containing protein 2 OS=Bos taurus OX=9913 GN=RPRD2 PE=4 SV=2 CANONICAL=G3MZG3-1" }, "locus": { "chromosome": "3", "start_pos": 20302019, "end_pos": 20203830, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000019948.6", "url": "https://www.ensembl.org/id/ENSBTAT00000019948.6" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000019948.5", "url": "https://www.ensembl.org/id/ENSBTAP00000019948.5" } ] } }, { "isoform_ac": "G3MX56-1", "url": "https://www.uniprot.org/uniprotkb/G3MX56/entry", "sequence": { "sequence": "MAAGGGGGGSKASSSSASSAGALESSLDRKFQSVTNTMESIQGLSSWCIENKKHHTTIVYHWMKWLRRSAYPHRLNLFYLANDVIQNCKRKNAIIFRESFADVLPEAAALVKDPSVSKSIERIFKIWEDRNVYPEEMIMALREALSTTFKTQKQLKENLNKQPNKQWKKSQTSTNPKAALKSKIVAEFRSQALIEELLLYKRSEDQIELKEKQLSTMRVDVCSTETLKCLKDKTGGKKFSKEFEEASAKLEEFVNGLDKQVKNGPSLTEALENAGIFYEAQYKEVKVVANAYKTFANRVNNLKKKLDQLKSTLPDPEESPVPSPSVDAPSPTGSESPFQGMGGEESQSPNAESEKSATPEPATDNRDVEDMDLSDVEDDGSKIIVEDRKEKPVEKSTVSTAVPTKPTESISKASSCTPAPVTMTATPPLPKPVNTSLLSPTPALALPNLANVDLAKISSILSSLTSVMKNTGLSSLLQSVTGNPVPSSEATPQSTSASPANTTVSSIKGRNLPSNTQSFIPKSFNYSPNSSTSEVSSTSASKASIGQSPGLPSTTFKLPSNTLGFTGNHSASPAAPPTEVAMCQSSEASKPKLESESTSPSLEMKIHNFLKGNPGFSGLNLNIPILSSLGSSAPAESHPSDFQRGPTSTSVDNIDGTPVRDERSGTPTQDEMMDKPTSSSVDTMSLLSKIISPGSSTPSSTRSPPPGREESFPRELSSSVSTFRPFGLGSDSPYKQPSDGMERPSSLMDSSQEKFYPDTSFQEDEDYRDFEYSGPPPSAMMNLEKKPAKSILKSSKLSDTTEYQPILSSYSHRGQEFGVKSAFPASVRALLDSSENCGRLSSPPGLFSAFGVRGNEAGSDRSPSPSKNDSFFTPDSNHNSLSQSATGHLTLPQKQYPDSPHPVPHRSLFSPQNTLAAPTGHPPTSGVEKVLASTISTTSTIEFKNMLKNASRKPSDDKHFGQAPNKGTSSDGVSLSNLAQLSLTAADQQQQEEHYRIETRVSSSCLDLPDSTEEKGAPIETLGYHNASSRRMSGEPIQTVESIRVPGKGNRGHGREASRVGWFDLSTSGGSFDNGPSSASELASLGGGGSGGLTGFKTAPYKERAPQFQESVGSFRSNSFNSTFEHHLPPSPLDHGTPFQREPVGPSSAPPAPPKDHGGIFSRDAPTHLPSVDLSNPFAKEAALTHAAPPPGEHGGVPFPTPPPPPPPGEHSSSGGSGVPFSAPPPPPPPGDHSGVVPFPTPPLAEHGVAGAVAVFPKDHSSLLQGTLADHFGVLPGPRDHGGPTQRDLNGPGLSRVRESLSLPSHSLEHLGPAHGGGGGGGSNSSSGPPLGPSHRDAINRSGMILRSPRPDFRPREPFLSRDPFHSLKRPRPPFARGPPFFAPKRPFFPPRY", "length": 1393, "header": "tr|G3MX56-1|G3MX56_BOVIN Computationally mapped isoform of Regulation of nuclear pre-mRNA domain-containing protein 2 OS=Bos taurus OX=9913 GN=RPRD2 PE=4 SV=3 CANONICAL=G3MZG3-1" }, "locus": { "chromosome": "3", "start_pos": 20302019, "end_pos": 20211415, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000063685.3", "url": "https://www.ensembl.org/id/ENSBTAT00000063685.3" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000054116.3", "url": "https://www.ensembl.org/id/ENSBTAP00000054116.3" } ] } }, { "isoform_ac": "G3MZG3-1", "url": "https://www.uniprot.org/uniprotkb/G3MZG3/entry", "sequence": { "sequence": "MAAGGGGGGSKASSSSASSAGALESSLDRKFQSVTNTMESIQGLSSWCIENKKHHTTIVYHWMKWLRRSAYPHRLNLFYLANDVIQNCKRKNAIIFRESFADVLPEAAALVKDPSVSKSIERIFKIWEDRNVYPEEMIMALREALSTTFKTQKQLKENLNKQPNKQWKKSQTSTNPKAALKSKIVAEFRSQALIEELLLYKRSEDQIELKEKQLSTMRVDVCSTETLKCLKDKTGGKKFSKEFEEASAKLEEFVNGLDKQVKNGPSLTEALENAGIFYEAQYKEVKVVANAYKTFANRVNNLKKKLDQLKSTLPDPEESPVPSPSVDAPSPTGSESPFQGMGGEESQSPNAESEKSATPEPATDNRDVEDMDLSDVEDDGSKIIAVEDRKEKPVEKSTVSTAVPTKPTESISKASSCTPAPVTMTATPPLPKPVNTSLLSPTPALALPNLANVDLAKISSILSSLTSVMKNTGVSPASRPSPGTPTSPSSLTSGLKTPAPATTTSHNPLANILSKVEITPESILSALSKTQTQSAPALQGLSSLLQSVTGNPVPSSEATPQSTSASPANTTVSSIKGRNLPSNTQSFIPKSFNYSPNSSTSEVSSTSASKASIGQSPGLPSTTFKLPSNTLGFTGNHSASPAAPPTEVAMCQSSEASKPKLESESTSPSLEMKIHNFLKGNPGFSGLNLNIPILSSLGSSAPAESHPSDFQRGPTSTSVDNIDGTPVRDERSGTPTQDEMMDKPTSSSVDTMSLLSKIISPGSSTPSSTRSPPPGREESFPRELSSSVSTFRPFGLGSDSPYKQPSDGMERPSSLMDSSQEKFYPDTSFQEDEDYRDFEYSGPPPSAMMNLEKKPAKSILKSSKLSDTTEYQPILSSYSHRGQEFGVKSAFPASVRALLDSSENCGRLSSPPGLFSAFGVRGNEAGSDRSPSPSKNDSFFTPDSNHNSLSQSATGHLTLPQKQYPDSPHPVPHRSLFSPQNTLAAPTGHPPTSGVEKVLASTISTTSTIEFKNMLKNASRKPSDDKHFGQAPNKGTSSDGVSLSNLAQLSLTAADQQQQEEHYRIETRVSSSCLDLPDSTEEKGAPIETLGYHNASSRRMSGEPIQTVESIRVPGKGNRGHGREASRVGWFDLSTSGGSFDNGPSSASELASLGGGGSGGLTGFKTAPYKERAPQFQESVGSFRSNSFNSTFEHHLPPSPLDHGTPFQREPVGPSSAPPAPPKDHGGIFSRDAPTHLPSVDLSNPFAKEAALTHAAPPPGEHGGVPFPTPPPPPPPGEHSSSGGSGVPFSAPPPPPPPGDHSGVVPFPTPPLAEHGVAGAVAVFPKDHSSLLQGTLADHFGVLPGPRDHGGPTQRDLNGPGLSRVRESLSLPSHSLEHLGPAHGGGGGGGSNSSSGPPLGPSHRDAINRSGMILRSPRPDFRPREPFLSRDPFHSLKRPRPPFARGPPFFAPKRPFFPPRY", "length": 1461, "header": "tr|G3MZG3-1|G3MZG3_BOVIN Isoform 1 of Regulation of nuclear pre-mRNA domain-containing protein 2 OS=Bos taurus OX=9913 GN=RPRD2 PE=4 SV=3 CANONICAL=G3MZG3-1" }, "locus": { "chromosome": "3", "start_pos": 20302019, "end_pos": 20211415, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000065820.3", "url": "https://www.ensembl.org/id/ENSBTAT00000065820.3" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000054960.3", "url": "https://www.ensembl.org/id/ENSBTAP00000054960.3" } ] } } ], "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "other", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 1269, "start_aa": "Thr", "end_pos": 1269, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr1269", "evidence": [ { "id": "", "database": "GlyGen", "url": "https://data.glygen.org/" } ], "filter_code": "000000000000000010000.00000000001000.0.01000" }, { "glytoucan_ac": "", "type": "O-linked", "subtype": "other", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 1309, "start_aa": "Thr", "end_pos": 1309, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr1309", "evidence": [ { "id": "", "database": "GlyGen", "url": "https://data.glygen.org/" } ], "filter_code": "000000000000000010000.00000000001000.0.01000" }, { "glytoucan_ac": "", "type": "O-linked", "subtype": "other", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 442, "start_aa": "Thr", "end_pos": 442, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr442", "evidence": [ { "id": "", "database": "GlyGen", "url": "https://data.glygen.org/" } ], "filter_code": "000000000000000010000.00000000001000.0.01000" }, { "glytoucan_ac": "", "type": "O-linked", "subtype": "other", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 765, "start_aa": "Thr", "end_pos": 765, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr765", "evidence": [ { "id": "", "database": "GlyGen", "url": "https://data.glygen.org/" } ], "filter_code": "000000000000000010000.00000000001000.0.01000" } ], "phosphorylation": [], "glycation": [], "keywords": [ "glycoprotein", "glycoprotein_predicted" ], "publication": [], "pathway": [ { "id": "R-BTA-6807505", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-BTA-6807505", "resource": "Reactome", "description": "RNA polymerase II transcribes snRNA genes" } ], "orthologs": [ { "uniprot_canonical_ac": "A0A0G2JTD1-1", "protein_name": "Regulation of nuclear pre-mRNA domain-containing protein 2", "gene_name": "Rprd2", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MAAGGGGGSSKASSSSASSAGALESSLDRKFQSVTNTMESIQGLSSWCIENKKHHSTIVYHWMKWLRRSTYPHRLNLFYLANDVIQNCKRKNAIIFRESFADVLPEAAALVKDPSVSKSIERIFKIWEDRNVYPEDMIVALREALSTTFKTQKQLKENLNKQPNKQWKKSQTSTNPKAALKSKIVAEFRSQALIEELLMYKRSEDQIELKEKQLSTMRVDVCSTETLKCLKDKTGGKKFSKEFEEASSKLEEFVNGLDKQVKNGPSLTEALENAGIFYEAQYKEVKVVANAYKTFANRVNNLKKKLDQLKSTLPDPEESPVPSPSMDAPSPTGSESPFQGMGGEESQSPTMESDKSATPEPVTDNRDVEDMELSDVEDDGSKIIVEDRKEKPVEKPAVSTGVVTKSTENISKTSPCAPPSVPTTAAPPLPKPLNTSLLSPSPTLVLPNLANVDLAKISSILSSLTSVMKNTGVSSASRPSPGTPTSPSSLSSGLKTPAPATTPSHNPLANILSKVEITPESILSALSKTQTQSAPALQGLSSLLQSVTGNPVPASEAASQSTAASPASTTGSAVKGRNLLSNTQSFISKSFNYSPNSSTSEVSSTSASKASVGQSPVLPSTTFKLPSSSLGFTGTHNTSPAAPPTEVAMCQSSEVSKPKPESESTSPSLEMKIHNFLKGNPGFSGLNLNIPILSSLGSSAPSEGHSSDFQRGPTSTSVDNIDGTPVRDERSGTPTQDEMMDKPTSSSVDTMSLLSKIISPGSSTPSSIRSPPAGGDESYPQEPPSSVSTYRPFGLGGGSPYKQSSSAVERPSSLMDSSQEKLFPDTSFQEDEDYRDFEYSGPPPSAMMNLEKKPAKSILKSSKLSDATEYQPILSSYNHRAQEFGGKSAFPPSVRALLDSSENCDRLSSPPGLFGAFSIRGSEPGSERSPSPSKNDSFFTPDSNHSGLSQSTAGHLTLPQTQYPDSPHSVPHRSVFSSQNTLAAPAGHPPTSGVEKVLASTISTTSTIEFKNMLKNASRKPSDDKHFGQTPNKGTSSDGVSLSNLTQPSLPTTDQQQEEHYRIETRVSSSCLDLPDSTEEKGAPIETLGYHNAANRRMSGEPIQTVESVRVPGKGNRGHGREVSRVGWFDLSTPGSSFDNGPSSASELASLGGGGSGGLTGFKTTPYKERAPQFQESVTSFRSNSFNSTFEHHLPPSPLEHGTPFQREPVGPSSAPPAPPKDHGGIFSREAPTHLPSVDLSNPFTKEASLAHAGPPPPPGEHSGVPFPPPPPPPPPGELSSGGSGVPFATPPPPPPPVDHSGVVPFPTPPLPEHGVTGAVAVFPKDHSSLLQGTMAEHFGVLTGPRDLNGPGLSRARESLSLPSHPLDHLGPALGGGGGGNSSSSGLPLGPAHRDAISRSGVVFRSPRPDFRPREAFLGRDPFHSLKRPRPPFVRGPPFFAPKRPFFPPRRSYISEDGAPEWPMTRVSCPPQTELWAFLEA", "length": 1481 }, "evidence": [ { "id": "G3MZG3", "url": "https://omabrowser.org/oma/group/G3MZG3/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "Q5VT52-1", "protein_name": "Regulation of nuclear pre-mRNA domain-containing protein 2", "gene_name": "RPRD2", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MAAGGGGGSSKASSSSASSAGALESSLDRKFQSVTNTMESIQGLSSWCIENKKHHSTIVYHWMKWLRRSAYPHRLNLFYLANDVIQNCKRKNAIIFRESFADVLPEAAALVKDPSVSKSVERIFKIWEDRNVYPEEMIVALREALSTTFKTQKQLKENLNKQPNKQWKKSQTSTNPKAALKSKIVAEFRSQALIEELLLYKRSEDQIELKEKQLSTMRVDVCSTETLKCLKDKTGGKKFSKEFEEASSKLEEFVNGLDKQVKNGPSLTEALENAGIFYEAQYKEVKVVANAYKTFANRVNNLKKKLDQLKSTLPDPEESPVPSPSMDAPSPTGSESPFQGMGGEESQSPTMESEKSATPEPVTDNRDVEDMELSDVEDDGSKIIVEDRKEKPAEKSAVSTSVPTKPTENISKASSCTPVPVTMTATPPLPKPVNTSLSPSPALALPNLANVDLAKISSILSSLTSVMKNTGVSPASRPSPGTPTSPSNLTSGLKTPAPATTTSHNPLANILSKVEITPESILSALSKTQTQSAPALQGLSSLLQSVTGNPVPASEAASQSTSASPANTTVSTIKGRNLPSSAQPFIPKSFNYSPNSSTSEVSSTSASKASIGQSPGLPSTTFKLPSNSLGFTATHNTSPAAPPTEVTICQSSEVSKPKLESESTSPSLEMKIHNFLKGNPGFSGLNLNIPILSSLGSSAPSESHPSDFQRGPTSTSIDNIDGTPVRDERSGTPTQDEMMDKPTSSSVDTMSLLSKIISPGSSTPSSTRSPPPGRDESYPRELSNSVSTYRPFGLGSESPYKQPSDGMERPSSLMDSSQEKFYPDTSFQEDEDYRDFEYSGPPPSAMMNLEKKPAKSILKSSKLSDTTEYQPILSSYSHRAQEFGVKSAFPPSVRALLDSSENCDRLSSSPGLFGAFSVRGNEPGSDRSPSPSKNDSFFTPDSNHNSLSQSTTGHLSLPQKQYPDSPHPVPHRSLFSPQNTLAAPTGHPPTSGVEKVLASTISTTSTIEFKNMLKNASRKPSDDKHFGQAPSKGTPSDGVSLSNLTQPSLTATDQQQQEEHYRIETRVSSSCLDLPDSTEEKGAPIETLGYHSASNRRMSGEPIQTVESIRVPGKGNRGHGREASRVGWFDLSTSGSSFDNGPSSASELASLGGGGSGGLTGFKTAPYKERAPQFQESVGSFRSNSFNSTFEHHLPPSPLEHGTPFQREPVGPSSAPPVPPKDHGGIFSRDAPTHLPSVDLSNPFTKEAALAHAAPPPPPGEHSGIPFPTPPPPPPPGEHSSSGGSGVPFSTPPPPPPPVDHSGVVPFPAPPLAEHGVAGAVAVFPKDHSSLLQGTLAEHFGVLPGPRDHGGPTQRDLNGPGLSRVRESLTLPSHSLEHLGPPHGGGGGGGSNSSSGPPLGPSHRDTISRSGIILRSPRPDFRPREPFLSRDPFHSLKRPRPPFARGPPFFAPKRPFFPPRY", "length": 1461 }, "evidence": [ { "id": "G3MZG3", "url": "https://omabrowser.org/oma/group/G3MZG3/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "Q6NXI6-1", "protein_name": "Regulation of nuclear pre-mRNA domain-containing protein 2", "gene_name": "Rprd2", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MAAGGGGGSSKASSSSASSAGALESSLDRKFQSVTNTMESIQGLSSWCIENKKHHSTIVYHWMKWLRRSTYPHRLNLFYLANDVIQNCKRKNAIIFRESFADVLPEAAALVKDPSVSKSIERIFKIWEDRNVYPEDMIVALREALMDRAASHNARLQKLQCFPGTTFKTQKQLKENLNKQPNKQWKKSQTSTNPKAALKSKIVAEFRSQALIEELLMYKRSEDQIELKEKQLSTMRVDVCSTETLKCLKDKTGGKKFSKEFEEASSKLEEFVNGLDKQVKNGPSLTEALENAGIFYEAQYKEVKVVANAYKTFANRVNNLKKKLDQLKSTLPDPEESPVPSPSMDAPSPTGSESPFQGMGGEEPQSPAMESDKSATPEPVTDNRDVEDMELSDVEDDGSKIIVEDRKEKPVEKPAVSTGVPTKSTESVSKASPCAPPSVPTTAAPPLPKPLSTALLSPSPTLVLPNLANVDLAKISSILSSLTSVMKNTGVSSASRPSPGIPTSPSNLSSGLKTPAPATTPSHNPLANILSKVEITPESILSALSKTQTQSAPALQGLSSLLQSVTANPVPASEVTSQSTTASPASTTGSAVKGRNLLSSTQSFIPKSFNYSPSSSTSEVSSTSASKASVGQSPVLPSTTFKLPSSSLGFTGTHNPSPAAPPTEVAVCQSSEVSKPKPESESTSPSLEMKIHNFLKGNPGFSGLNLNIPILSSLGSSAPSEGHASDFQRGPTSTSVDSIDGTPVRDERSGTPTQDEMMDKPTSSSVDTMSLLSKIISPGSSTPSSTRSPPPGRDESYPQELPNSVSTYRPFGLGSDSPYKQPSGGVERPSSLMDSSQEKLFPDTSFQEDEDYRDFEYSGPPPSAMMNLEKKPAKSILKSSKLSDATEYQPILSSYNHRAQEFGVKSAFPPSVRALLDSSENCDRLSSPPGLFGAFNIRGNEPGSERSPSPSKNDAFFTPDSNHSGLSQSTAGHLTLPQTQYPDSPHSVPHRSIFSSQSTLAAPAGHPPTSGVEKVLASTISTTSTIEFKNMLKNASRKPSDDKHFGQTPNKGTSSDGVSLSNLTQPSLPTTDQQQEEHYRIETRVSSSCLDLPDSTEEKGAPIETLGYHNAANRRMSGEPIKTVESIRVPGKGNRGHGREVSRVGWFDLSTPGSSFDNGPSSASELASLGGGGSGGLTGFKTTPYKERAPQFQESVTSFRSNSFNSTFEHHLPPSPLEHGAPFQREPVGPSSAPPAPPKDHGGIFSREAPTHLPSVDLSNPFTKEASLAHAGPPPPPGEHSGVPFPPPPPPPPPGELSSGGTGVPFATPAPPPPPVDHSGVVPFPTPPLPEHGVTGAVSVFPKDHSSLLQGTMAEHFGVLTGPRDLNGPGLNRSRESLSLPSHPLEHLGPALGGGGGGNTSSSGLPLSPAHRDAIGRSGMILRSPRPDFRPREAFLGRDPFHSLKRPRPPFVRGPPFFAPKRPFFPPRY", "length": 1469 }, "evidence": [ { "id": "G3MZG3", "url": "https://omabrowser.org/oma/group/G3MZG3/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" } ], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 1, "go_terms": [ { "name": "transcription preinitiation complex", "id": "GO:0097550", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0097550", "evidence": [ { "database": "UniProtKB", "id": "G3MZG3", "url": "https://www.uniprot.org/uniprotkb/G3MZG3" } ], "pmid": "" } ] }, { "name": "Molecular Function", "total": 2, "go_terms": [ { "name": "RNA polymerase II complex binding", "id": "GO:0000993", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000993", "evidence": [ { "database": "UniProtKB", "id": "G3MZG3", "url": "https://www.uniprot.org/uniprotkb/G3MZG3" } ], "pmid": "" }, { "name": "RNA polymerase II C-terminal domain binding", "id": "GO:0099122", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0099122", "evidence": [ { "database": "UniProtKB", "id": "G3MZG3", "url": "https://www.uniprot.org/uniprotkb/G3MZG3" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 1, "go_terms": [ { "name": "mRNA 3'-end processing", "id": "GO:0031124", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0031124", "evidence": [ { "database": "UniProtKB", "id": "G3MZG3", "url": "https://www.uniprot.org/uniprotkb/G3MZG3" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 1017, "end_pos": 1019, "annotation": "n_glycosylation_sequon" }, { "start_pos": 1094, "end_pos": 1096, "annotation": "n_glycosylation_sequon" }, { "start_pos": 1189, "end_pos": 1191, "annotation": "n_glycosylation_sequon" }, { "start_pos": 1392, "end_pos": 1394, "annotation": "n_glycosylation_sequon" }, { "start_pos": 1408, "end_pos": 1410, "annotation": "n_glycosylation_sequon" }, { "start_pos": 435, "end_pos": 437, "annotation": "n_glycosylation_sequon" }, { "start_pos": 569, "end_pos": 571, "annotation": "n_glycosylation_sequon" }, { "start_pos": 593, "end_pos": 595, "annotation": "n_glycosylation_sequon" }, { "start_pos": 597, "end_pos": 599, "annotation": "n_glycosylation_sequon" }, { "start_pos": 636, "end_pos": 638, "annotation": "n_glycosylation_sequon" }, { "start_pos": 936, "end_pos": 938, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "G3MZG3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3MZG3" }, { "id": "PS51391", "database": "PROSITE", "url": "https://prosite.expasy.org/PS51391" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "CID", "eco_id": "ECO_0000259", "start_pos": 19, "end_pos": 149, "start_aa": "Ser", "end_aa": "Phe", "glycosite_overlap": [] } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" }, { "name": "homologset.oma", "label": "OMA Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [ 442, 765, 1269, 1309 ], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 1017, "end_pos": 1019 }, { "start_pos": 1094, "end_pos": 1096 }, { "start_pos": 1189, "end_pos": 1191 }, { "start_pos": 1392, "end_pos": 1394 }, { "start_pos": 1408, "end_pos": 1410 }, { "start_pos": 435, "end_pos": 437 }, { "start_pos": 569, "end_pos": 571 }, { "start_pos": 593, "end_pos": 595 }, { "start_pos": 597, "end_pos": 599 }, { "start_pos": 636, "end_pos": 638 }, { "start_pos": 936, "end_pos": 938 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 4 }, { "field": "total_sites", "count": 4 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 4 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "exact_sites", "count": 4 }, { "field": "exact_o_linked_sites", "count": 4 }, { "field": "fuzzy_sites", "count": 0 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_pos", "start_aa", "end_pos", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 4 }, { "field": "total_sites", "count": 4 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 4 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "exact_sites", "count": 4 }, { "field": "exact_o_linked_sites", "count": 4 }, { "field": "fuzzy_sites", "count": 0 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_pos", "start_aa", "end_pos", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ], "tool_support": { "graph_view": "yes" } }, { "uniprot_canonical_ac": "G3MZD5-1", "uniprot_ac": "G3MZD5", "uniprot_id": "G3MZD5_BOVIN", "mass": { "chemical_mass": 100677.0, "monoisotopic_mass": 100677.0 }, "refseq": { "ac": "XP_024840274", "name": "coiled-coil domain-containing protein 178", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_024840274" }, "gene_names": [ { "name": "CCDC178", "type": "recommended", "evidence": [ { "id": "G3MZD5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3MZD5" } ] }, { "name": "CCDC178", "type": "synonym", "evidence": [ { "id": "XP_024840274", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_024840274" } ] } ], "protein_names": [ { "name": "Coiled-coil domain containing 178", "type": "synonym", "evidence": [ { "id": "G3MZD5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3MZD5/entry#names_and_taxonomy" } ] }, { "name": "coiled-coil domain-containing protein 178", "type": "synonym", "evidence": [ { "id": "XP_024840274", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_024840274" } ] } ], "function": [], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Bos taurus", "taxid": 9913, "evidence": [ { "database": "UniProtKB", "id": "G3MZD5", "url": "https://www.uniprot.org/uniprotkb/G3MZD5" } ], "common_name": "Bovine", "glygen_name": "Bovine", "reference_species": "Bos taurus [9913]" } ], "gene": [ { "name": "CCDC178", "url": "https://www.uniprot.org/uniprotkb/G3MZD5", "locus": { "chromosome": "24", "start_pos": 24196101, "end_pos": 23812691, "strand": "-", "evidence": [ { "database": "Ensembl Gene", "id": "ENSBTAG00000000138", "url": "https://www.ensembl.org/id/ENSBTAG00000000138" } ] } } ], "crossref": [ { "id": "G3MZD5", "url": "https://alphafold.ebi.ac.uk/entry/G3MZD5", "database": "AlphaFoldDB", "categories": [] }, { "id": "ENSBTAG00000000138", "url": "https://bgee.org/?page=gene&gene_id=ENSBTAG00000000138", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "532148", "url": "https://www.ncbi.nlm.nih.gov/gene/532148", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR038826", "url": "https://www.ebi.ac.uk/interpro/entry/IPR038826", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "bta:532148", "url": "https://www.genome.jp/dbget-bin/www_bget?bta:532148", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "PTHR35088", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR35088", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR35088:SF1", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR35088:SF1", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "XP_024840274", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_024840274", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0AAA9S1M9", "url": "https://www.uniprot.org/uniprotkb/A0AAA9S1M9", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0AAA9S1M9-1", "url": "https://www.uniprot.org/uniprotkb/A0AAA9S1M9-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0AAA9SG80", "url": "https://www.uniprot.org/uniprotkb/A0AAA9SG80", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0AAA9SG80-1", "url": "https://www.uniprot.org/uniprotkb/A0AAA9SG80-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "F1MFC7", "url": "https://www.uniprot.org/uniprotkb/F1MFC7", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "F1MFC7-1", "url": "https://www.uniprot.org/uniprotkb/F1MFC7-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "G3MZD5", "url": "https://www.uniprot.org/uniprotkb/G3MZD5", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "G3MZD5-1", "url": "https://www.uniprot.org/uniprotkb/G3MZD5-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MPEKKIISCSPIGGEQTKKDNATSQALVRFVTPEEAVEVIHEDKMTNTEELNKGLYFGYPCRRESCALVNIPAPCVNKMIAHIEDVESKIQEHLKRFETSLEEWSRTSFTEDLKKDLSVVTLVKEPKPEELRDEKCPELKQKMETLLSEAIHLIKSLETDRAEAEEALQRQKSRKKRITTQIDSWSIWKLQEIPLAVQNEHEAYLRDIIELRWHFEDKTRQRKHLEEQKEKLAETNSKLKADIDYMIKQHPLLLAKRDHELISLREYYQKKFEVMEIYKQVHGELLEAIDNLEKAKLRVKQNRIEMERDIRDDEISMAAYKKEIDKLSNLFNFYCTSIQDININIEENEEAVTEVLRETKSSKNELTALEKTLDDLKRLYDQLHWKRKIYESEYLEVLNNFYAMKSTWDTELSNIAKDFSDISIACSQLVEENKRLSTDIDTVLGYINDSIRKKSELESEIQSLLKMRSRNEEFLKQLYNEAYNIGAIYHLTRFKTEELEQKVAEVRRKFKGREDFLKKLTRGEVANGMMIQKKLFSLQEEQTLEKQDLMRKKAIYSLALAEMEKPLLKLEEEAEKIKTCHQEHADLLDEVLEKRGEVKRNVEKTKKKLQRKGKKTQDAIIKTEDKRSQIFKEIETTKSKTIVYHSKIIQLNKNLEQKEKEKIAFDHTLDYLNDQFITLREKKEHAQAVFDHLVNEKKACEERLYEEEQRYRTLFNMRQKTLASIKKIQDDSLEENLRLAQEYQRLQNIFLTVKDNYFSRFERQLSFDGSIRDKKQFCQLQRRIHKLWQKHFELVVFYSRMRLAKFQTDSQESIQKILVVQEESSNLMQHILDFFQTLTDGQCENDG", "length": 847, "header": "tr|G3MZD5-1|G3MZD5_BOVIN Isoform 1 of Coiled-coil domain containing 178 OS=Bos taurus OX=9913 GN=CCDC178 PE=4 SV=3 CANONICAL=G3MZD5-1" }, "isoforms": [ { "isoform_ac": "A0AAA9S1M9-1", "url": "https://www.uniprot.org/uniprotkb/A0AAA9S1M9/entry", "sequence": { "sequence": "MPEKKIISCSPIGGEQTKKDNATSQALVRFVTPEEAVEVIHEDKMTNTEELNKGLYFGYPCRRESCALVNIPAPCVNKMIAHIEDVESKIQEHLKRFETSLEEWSRTSFTEDLKKDLSVVTLVKEPKPEELRDEKCPELKQKMETLLSEAIHLIKSLETDRAEAEEALQRQKSRKKRITTQIDSWSIWKLQEIPLAVQNEHEAYLRDIIELRWHFEDKTRQRKHLEEQKEKLAETNSKLKADIDYMIKQHPLLLAKRDHELISLREYYQKKFEVMEIYKQVHGELLEAIDNLEKAKLRVKQNRIEMERDIRDDEISMAAYKKEIDKLSNLFNFYCTSIQDININIEENEEAVTEVLRETKSSKNELTALEKTLDDLKRLYDQLHWKRKIYESEYLEVLNNFYAMKSTWDTELSNIAKDFSDISIACSQLVEENKRLSTDIDTVLGYINDSIRKKSELESEIQSLLKMRSRNEEFLKQLYNEAYNIGAIYHLTRFKTEELEQKVAEVRRKFKGREDFLKKLTRGEVANGMMIQKKLFSLQEEQTLEKQDLMRKKAIYSLALAEMEKPLLKLEEEAEKIKTCHQEHADLLDEVLEKRGEVKRNVEKTKKKLQRKGKKTQDAIIKTEDKRSQIFKEIETTKSKTIVYHSKIIQLNKNLEQKEKEKIAFDHTLDYLNDQFITLREKKEHAQAVFDHLVNEKKACEERLYEEEQRYRTLFNMRQKTLASIKKIQDDSLEENLRLAQEYQRLQNIFLTVKDNYFSRFERQLSFDGSIRDKKQFCQLQRRIHKLWQKHFELVVFYSRMRLAKFQTDSQESIQKILVVQNQYDLKKE", "length": 829, "header": "tr|A0AAA9S1M9-1|G3MZD5_BOVIN Computationally mapped isoform of Coiled-coil domain containing 178 OS=Bos taurus OX=9913 GN=CCDC178 PE=4 SV=1 CANONICAL=G3MZD5-1" }, "locus": { "chromosome": "24", "start_pos": 24172969, "end_pos": 23812716, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000093748.1", "url": "https://www.ensembl.org/id/ENSBTAT00000093748.1" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000077590.1", "url": "https://www.ensembl.org/id/ENSBTAP00000077590.1" } ] } }, { "isoform_ac": "A0AAA9SG80-1", "url": "https://www.uniprot.org/uniprotkb/A0AAA9SG80/entry", "sequence": { "sequence": "MFCQLQRRIHKLWQKHFELVVFYSRMRLAKFQTDSQESIQKILVVQEESSNLMQHILDFFQTLTDGQCENDG", "length": 72, "header": "tr|A0AAA9SG80-1|G3MZD5_BOVIN Computationally mapped isoform of Coiled-coil domain containing 178 OS=Bos taurus OX=9913 GN=CCDC178 PE=4 SV=1 CANONICAL=G3MZD5-1" }, "locus": { "chromosome": "24", "start_pos": 24195824, "end_pos": 24014127, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000117739.1", "url": "https://www.ensembl.org/id/ENSBTAT00000117739.1" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000082879.1", "url": "https://www.ensembl.org/id/ENSBTAP00000082879.1" } ] } }, { "isoform_ac": "F1MFC7-1", "url": "https://www.uniprot.org/uniprotkb/F1MFC7/entry", "sequence": { "sequence": "MPEKKIISCSPIGGEQTKKDNATSQALVRFVTPEEAVEVIHEDKMTNTEELNKGLYFGYPCRRESCALVNIPAPCVNKMIAHIEDVESKIQEHLKRFETSLEEWSRTSFTEDLKKDLSVVTLVKEPKPEELRDEKCPELKQKMETLLSEAIHLIKSLETDRAEAEEALQRQKSRKKRITTQIDSWSIWKLQEIPLAVQNEHEAYLRDIIELRWHFEDKTRQRKHLEEQKEKLAETNSKLKADIDYMIKQHPLLLAKRDHELISLREYYQKKFEVMEIYKQVHGELLEAIDNLEKAKLRVKQNRIEMERDIRDDEISMAAYKKEIDKLSNLFNFYCTSIQDININIEENEEAVTEVLRETKSSKNELTALEKTLDDLKRLYDQLHWKRKIYESEYLEVLNNFYAMKSTWDTELSNIAKDFSDISIACSQLVEENKRLSTDIDTVLGYINDSIRKKSELESEIQSLLKMRSRNEEFLKQLYNEAYNIGAIYHLTRFKTEELEQKVAEVRRKFKGREDFLKKLTRGEVANGMMIQKKLFSLQEEQTLEKQDLMRKKAIYSLALAEMEKPLLKLEEEAEKIKTCHQEHADDKRSQIFKEIETTKSKTIVYHSKIIQLNKNLEQKEKEKIAFDHTLDYLNDQFITLREKKEHAQAVFDHLVNEKKACEERLYEEEQRYRTLFNMRQKTLASIKKIQDDSLEENLRLAQEYQRLQNIFLTVKDNYFSRFERQLSFDGSIRDKKQFCQLQRRIHKLWQKHFELVVFYSRMRLAKFQTDSQESIQKILVVQEESSNLMQHILDFFQTLTDGQCENDG", "length": 809, "header": "tr|F1MFC7-1|G3MZD5_BOVIN Computationally mapped isoform of Coiled-coil domain containing 178 OS=Bos taurus OX=9913 GN=CCDC178 PE=4 SV=3 CANONICAL=G3MZD5-1" }, "locus": { "chromosome": "24", "start_pos": 24195824, "end_pos": 23812716, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000000161.6", "url": "https://www.ensembl.org/id/ENSBTAT00000000161.6" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000000161.6", "url": "https://www.ensembl.org/id/ENSBTAP00000000161.6" } ] } }, { "isoform_ac": "G3MZD5-1", "url": "https://www.uniprot.org/uniprotkb/G3MZD5/entry", "sequence": { "sequence": "MPEKKIISCSPIGGEQTKKDNATSQALVRFVTPEEAVEVIHEDKMTNTEELNKGLYFGYPCRRESCALVNIPAPCVNKMIAHIEDVESKIQEHLKRFETSLEEWSRTSFTEDLKKDLSVVTLVKEPKPEELRDEKCPELKQKMETLLSEAIHLIKSLETDRAEAEEALQRQKSRKKRITTQIDSWSIWKLQEIPLAVQNEHEAYLRDIIELRWHFEDKTRQRKHLEEQKEKLAETNSKLKADIDYMIKQHPLLLAKRDHELISLREYYQKKFEVMEIYKQVHGELLEAIDNLEKAKLRVKQNRIEMERDIRDDEISMAAYKKEIDKLSNLFNFYCTSIQDININIEENEEAVTEVLRETKSSKNELTALEKTLDDLKRLYDQLHWKRKIYESEYLEVLNNFYAMKSTWDTELSNIAKDFSDISIACSQLVEENKRLSTDIDTVLGYINDSIRKKSELESEIQSLLKMRSRNEEFLKQLYNEAYNIGAIYHLTRFKTEELEQKVAEVRRKFKGREDFLKKLTRGEVANGMMIQKKLFSLQEEQTLEKQDLMRKKAIYSLALAEMEKPLLKLEEEAEKIKTCHQEHADLLDEVLEKRGEVKRNVEKTKKKLQRKGKKTQDAIIKTEDKRSQIFKEIETTKSKTIVYHSKIIQLNKNLEQKEKEKIAFDHTLDYLNDQFITLREKKEHAQAVFDHLVNEKKACEERLYEEEQRYRTLFNMRQKTLASIKKIQDDSLEENLRLAQEYQRLQNIFLTVKDNYFSRFERQLSFDGSIRDKKQFCQLQRRIHKLWQKHFELVVFYSRMRLAKFQTDSQESIQKILVVQEESSNLMQHILDFFQTLTDGQCENDG", "length": 847, "header": "tr|G3MZD5-1|G3MZD5_BOVIN Isoform 1 of Coiled-coil domain containing 178 OS=Bos taurus OX=9913 GN=CCDC178 PE=4 SV=3 CANONICAL=G3MZD5-1" }, "locus": { "chromosome": "24", "start_pos": 24195824, "end_pos": 23812716, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000066348.3", "url": "https://www.ensembl.org/id/ENSBTAT00000066348.3" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000054932.3", "url": "https://www.ensembl.org/id/ENSBTAP00000054932.3" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [ { "id": "bta:532148", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?bta:532148", "resource": "KEGG Pathway" } ], "orthologs": [], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 2, "go_terms": [ { "name": "centrosome", "id": "GO:0005813", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005813", "evidence": [ { "database": "UniProtKB", "id": "G3MZD5", "url": "https://www.uniprot.org/uniprotkb/G3MZD5" } ], "pmid": "" }, { "name": "ciliary basal body", "id": 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Computationally mapped isoform of Maestro heat like repeat family member 8 OS=Bos taurus OX=9913 GN=MROH8 PE=4 SV=4 CANONICAL=G3MWQ0-1" }, "locus": { "chromosome": "13", "start_pos": 66143601, "end_pos": 66086812, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000018251.7", "url": "https://www.ensembl.org/id/ENSBTAT00000018251.7" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000018251.7", "url": "https://www.ensembl.org/id/ENSBTAP00000018251.7" } ] } }, { "isoform_ac": "G3MWQ0-1", "url": "https://www.uniprot.org/uniprotkb/G3MWQ0/entry", "sequence": { "sequence": "MPLPRRGRGTLLAAPRMASTSPSRATAHSPNPAQRLTRQRHSSEQVPPGPEPQADFRSKRWLQKGSGGDAGNSRQTPCAGMGSRHRICGREEIVMPYASDSDSGSVDLQLGNLEDIKKQPSSLELTDSDISEIPGLPRESLTDTSRHLTHQGPLGEVVVEQLIQSIQKFFNGELKSELEKLTALRSLSSLSRTLPSDETTESFIHSHIADIVHLLSTLVECQDVYLLFGSEDRADLFSLVTKSVIALPSIKTLIHPQEIMPGGSCNSEYLYRRTFQAFVEMLQSLVIKDRHLENLDIIFKHMDPWLRSDKDHERERATASMTQVLKCLFKHLSLQLPVQFQRLGHLVALMALLCGDPLKEVAEEAAEGMHYLLHITLRLKCITYDKKNRQCLKRAVKKCRELLELYNVKQFYSCPFRIAQVFEVFLNSNELYQFVMATLDGLKNLKHPHTQRSAGELLKALVKNAQSRFEKVPEIMGVICALLSTSSQPNVRQQITNIVSLLMSRPKYTDTVIDHLLCHPVPYDRHLAELWRTLEVELPKTTWILWRLLRKLQKCHDSDSQDKMAYVAVAVTDALYEVFVGNRLRAATFRLFPQLLMTLLVQVHHAIGLTMSDVAIPSGLYPEQEVSSEVTPLCFAIQATKTLLLRTFCWQEFNIMEKNKGWTLLEGKDCHLQGVSLLANALLERNHLLAHKVMYLLVPFLNRGNDKHKLTSAGFFVELLQSPVARRFPSIYCVARLKDWLLLENNPFKILALRGLCYLTRQEEMREDIKSLLPCILDLLCESDEKIVLLAIQILLQFVRTMDFTTLTAMMKTLFSLFGDVRPDVHRFSMTLFGASIKSVKYADKKGVESQVLDSLVPLLLYSQDENDAIATESRQVLTICARFLKWKLPQAVYCKDPWFINPSDVATICKFFGKKCKGKVNILAQTLMFSKNAKLPIRRAAVLFVGLLSRYVDHSELGTKGTDRIEDDLKKLLHDPEPSLRIIASQALFRIQKAGAELHSRQTLFGLRKLIGCLPF", "length": 1017, "header": "tr|G3MWQ0-1|G3MWQ0_BOVIN Isoform 1 of Maestro heat like repeat family member 8 OS=Bos taurus OX=9913 GN=MROH8 PE=4 SV=3 CANONICAL=G3MWQ0-1" }, "locus": { "chromosome": "13", "start_pos": 66143601, "end_pos": 66086812, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000063909.3", "url": "https://www.ensembl.org/id/ENSBTAT00000063909.3" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000053953.3", "url": "https://www.ensembl.org/id/ENSBTAP00000053953.3" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [], "orthologs": [], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 1, "go_terms": [ { "name": "cytoplasm", "id": "GO:0005737", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005737", "evidence": [ { "database": "UniProtKB", "id": "G3MWQ0", "url": "https://www.uniprot.org/uniprotkb/G3MWQ0" } ], "pmid": "" } ] } ] }, 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[], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Bos taurus", "taxid": 9913, "evidence": [ { "database": "UniProtKB", "id": "G3MX83", "url": "https://www.uniprot.org/uniprotkb/G3MX83" } ], "common_name": "Bovine", "glygen_name": "Bovine", "reference_species": "Bos taurus [9913]" } ], "gene": [ { "name": "CCDC171", "url": "https://www.uniprot.org/uniprotkb/G3MX83", "locus": { "chromosome": "8", "start_pos": 28432123, "end_pos": 28771603, "strand": "+", "evidence": [ { "database": "Ensembl Gene", "id": "ENSBTAG00000015788", "url": "https://www.ensembl.org/id/ENSBTAG00000015788" } ] } } ], "crossref": [ { "id": "ENSBTAG00000015788", "url": "https://bgee.org/?page=gene&gene_id=ENSBTAG00000015788", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "538331", "url": "https://www.ncbi.nlm.nih.gov/gene/538331", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR038820", "url": "https://www.ebi.ac.uk/interpro/entry/IPR038820", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "bta:538331", "url": "https://www.genome.jp/dbget-bin/www_bget?bta:538331", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "PTHR47899", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR47899", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR47899:SF1", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR47899:SF1", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF28256", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF28256", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "XP_003586424", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_003586424", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0AAA9T9R5", "url": "https://www.uniprot.org/uniprotkb/A0AAA9T9R5", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0AAA9T9R5-1", "url": "https://www.uniprot.org/uniprotkb/A0AAA9T9R5-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "F1MQ32", "url": "https://www.uniprot.org/uniprotkb/F1MQ32", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "F1MQ32-1", "url": "https://www.uniprot.org/uniprotkb/F1MQ32-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "G3MX83", "url": "https://www.uniprot.org/uniprotkb/G3MX83", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "G3MX83-1", "url": "https://www.uniprot.org/uniprotkb/G3MX83-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MNSNTSSNTPGDIQRLKNASSDIKQIVKSETDLDITADLRKKLHRAKKEKLEITTKHNAELASYESQIAKLRSEVEKGEALRQSLEYDLAVARKEAGLGRRAAEERLAEAHRIQEKLCAQNVELQGKANEIEKAFQISQQKWKEECRRFEHDLEERDNIIQNCHQEYDLLTKEKSRLEKTLQEALEKHQEEKNEMESHIRETALEELRLQAEQWEAERRELQFIVQEQDNAVQNMHKKVEKLEAEHMECSDLLRRQTSELEFSTQREERLRKEFEATTLRVRKLEENIEAERAAHLESKFNSEIIQLRIRDLEGALQVEKASQAEAVADLEMIKNEFKEVESAYEREKHNAQESFAKLNVLEREYFSKNKKLNEEIEEQKKVILDLSKRLQYNEKSCSELQEELVMAKKHQAFLVETCENNVKELESILDSFSVSGQWTSGIHKDKDKPPSFSVVLETLRRTLTDYQNKLEEASNELSNMNNAKEKASNELDSTKQKIESHTKNIKDLQDKLADVSKELSHLRTKCADREALINTLKVELQNVLHCWEKEKARAAQSESELEKLSQAFHKDAEEKLTFLHTLYQHLIAGSVLIKQPEGMLDKFSWPELCAVLQENVDALIVDLNRANEKISHLEYICKNKSDTMKELQQTQEDTFNKVAEQIKAQESCWHKQKKELELQYSELLLEVQKRAQKFQEIAEKNMEKLNRIEKSHEQLVFENSHFKNLLSQTKREKTSLLVACALMAGAFYPLYSRSSALSTQRDFLQEQVNTFELLKLEVRTLAQALSTVEEKKQEEAKMKKKTFKGLIRVFRKGVIAILAANRLKILGQSCVSLFTWMESFREGIGVLVCTGELKDKHKFPKHQKEQLRCLQALSWLTSTDLLVAIISSMAEVQEAISKTDPNSRICGHLLIGAAKNSFAKLMDKISLAMDTMPLHNNRSITYVEKDSLVQRLARGLHKVNTLALKYGLQGHVPILKSTASLQKQIFGFTQRLHAAEVERRSLRLEVTELKRNLNEMKKELDKTQGLQMQLNEFKQSKLITHEKFESACEELNNALLREQQAQMLLNEQAQQLQELNYRLELHSSEEADKNQTLGEAVKSLSEAKMELRRKDQSLRQLNRHLTQLEQDKRRLEENIHDAESALRMAAKDKECVANHMRTVENMLHKVRDQISLSRTAASRNDFTLQLPRLHLETFAMEGLKGGPEVVACQAMIKSFVDVYQLASARIATLEKEMTSHRSHIATLKSELHTACLRENASLQSTGSRDHSNLSIPSRAALPADTTDVGDFLPLKAELDTTYTFLKETLINSVPLASSSNSSPVTMSATAKRPAQIGL", "length": 1334, "header": "tr|G3MX83-1|G3MX83_BOVIN Isoform 1 of Coiled-coil domain containing 171 OS=Bos taurus OX=9913 GN=CCDC171 PE=4 SV=3 CANONICAL=G3MX83-1" }, "isoforms": [ { "isoform_ac": "A0AAA9T9R5-1", "url": "https://www.uniprot.org/uniprotkb/A0AAA9T9R5/entry", "sequence": { "sequence": 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"length": 1259, "header": "tr|A0AAA9T9R5-1|G3MX83_BOVIN Computationally mapped isoform of Coiled-coil domain containing 171 OS=Bos taurus OX=9913 GN=CCDC171 PE=4 SV=2 CANONICAL=G3MX83-1" }, "locus": { "chromosome": "8", "start_pos": 28764493, "end_pos": 28433127, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000130075.2", "url": "https://www.ensembl.org/id/ENSBTAT00000130075.2" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000093377.2", "url": "https://www.ensembl.org/id/ENSBTAP00000093377.2" } ] } }, { "isoform_ac": "F1MQ32-1", "url": "https://www.uniprot.org/uniprotkb/F1MQ32/entry", "sequence": { "sequence": "MNSNTSSNTPGDIQRLKNASSDIKQIVKSETDLDITADLRKKLHRAKKEKLEITTKHNAELASYESQIAKLRSEVEKGEALRQSLEYDLAVARKEAGLGRRAAEERLAEAHRIQEKLCAQNVELQGKANEIEKAFQISQQKWKEECRRFEHDLEERDNIIQNCHQEYDLLTKEKSRLEKTLQEQDNAVQNMHKKVEKLEAEHMECSDLLRRQTSELEFSTQREERLRKEFEATTLRVRKLEENIEAERAAHLESKFNSEIIQLRIRDLEGALQVEKASQAEAVADLEMIKNEFKEVESAYEREKHNAQESFAKLNVLEREYFSKNKKLNEEIEEQKKVILDLSKRLQYNEKSCSELQEELVMAKKHQAFLVETCENNVKELESILDSFSVSGQWTSGIHKDKDKPPSFSVVLETLRRTLTDYQNKLEEASNELSNMNNAKEKASNELDSTKQKIESHTKNIKDLQDKLADVSKELSHLRTKCADREALINTLKVELQNVLHCWEKEKARAAQSESELEKLSQAFHKDAEEKLTFLHTLYQHLIAGSVLIKQPEGMLDKFSWPELCAVLQENVDALIVDLNRANEKISHLEYICKNKSDTMKELQQTQEDTFNKVAEQIKAQESCWHKQKKELELQYSELLLEVQKRAQKFQEIAEKNMEKLNRIEKSHEQLVFENSHFKNLLSQTKREKTSLLVACALMAGAFYPLYSRSSALSTQRDFLQEQVNTFELLKLEVRTLAQALSTVEEKKQEEAKMKKKTFKGLIRVFRKGVIAILAANRLKILGQSCVSLFTWMESFREGIGVLVCTGELKDKHKFPKHQKEQLRCLQALSWLTSTDLLVAIISSMAEVQEAISKTDPNSRICGHLLIGAAKNSFAKLMDKISLAMDTMPLHNNRSITYVEKDSLVQRLARGLHKVNTLALKYGLQGHVPILKSTASLQKQIFGFTQRLHAAEVERRSLRLEVTELKRNLNEMKKELDKTQGLQMQLNEFKQSKLITHEKFESACEELNNALLREQQAQMLLNEQAQQLQELNYRLELHSSEEADKNQTLGEAVKSLSEAKMELRRKDQSLRQLNRHLTQLEQDKRRLEENIHDAESALRMAAKDKECVANHMRTVENMLHKVRDQISLSRTAASRNDFTLQLPRLHLETFAMEGLKGGPEVVACQAMIKSFVDVYQLASARIATLEKEMTSHRSHIATLKSELHTACLRENASLQSNADIMAGT", "length": 1224, "header": "tr|F1MQ32-1|G3MX83_BOVIN Computationally mapped isoform of Coiled-coil domain containing 171 OS=Bos taurus OX=9913 GN=CCDC171 PE=4 SV=4 CANONICAL=G3MX83-1" }, "locus": { "chromosome": "8", "start_pos": 28764493, "end_pos": 28441752, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000020964.8", "url": "https://www.ensembl.org/id/ENSBTAT00000020964.8" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000020964.7", "url": "https://www.ensembl.org/id/ENSBTAP00000020964.7" } ] } }, { "isoform_ac": "G3MX83-1", "url": "https://www.uniprot.org/uniprotkb/G3MX83/entry", "sequence": { "sequence": "MNSNTSSNTPGDIQRLKNASSDIKQIVKSETDLDITADLRKKLHRAKKEKLEITTKHNAELASYESQIAKLRSEVEKGEALRQSLEYDLAVARKEAGLGRRAAEERLAEAHRIQEKLCAQNVELQGKANEIEKAFQISQQKWKEECRRFEHDLEERDNIIQNCHQEYDLLTKEKSRLEKTLQEALEKHQEEKNEMESHIRETALEELRLQAEQWEAERRELQFIVQEQDNAVQNMHKKVEKLEAEHMECSDLLRRQTSELEFSTQREERLRKEFEATTLRVRKLEENIEAERAAHLESKFNSEIIQLRIRDLEGALQVEKASQAEAVADLEMIKNEFKEVESAYEREKHNAQESFAKLNVLEREYFSKNKKLNEEIEEQKKVILDLSKRLQYNEKSCSELQEELVMAKKHQAFLVETCENNVKELESILDSFSVSGQWTSGIHKDKDKPPSFSVVLETLRRTLTDYQNKLEEASNELSNMNNAKEKASNELDSTKQKIESHTKNIKDLQDKLADVSKELSHLRTKCADREALINTLKVELQNVLHCWEKEKARAAQSESELEKLSQAFHKDAEEKLTFLHTLYQHLIAGSVLIKQPEGMLDKFSWPELCAVLQENVDALIVDLNRANEKISHLEYICKNKSDTMKELQQTQEDTFNKVAEQIKAQESCWHKQKKELELQYSELLLEVQKRAQKFQEIAEKNMEKLNRIEKSHEQLVFENSHFKNLLSQTKREKTSLLVACALMAGAFYPLYSRSSALSTQRDFLQEQVNTFELLKLEVRTLAQALSTVEEKKQEEAKMKKKTFKGLIRVFRKGVIAILAANRLKILGQSCVSLFTWMESFREGIGVLVCTGELKDKHKFPKHQKEQLRCLQALSWLTSTDLLVAIISSMAEVQEAISKTDPNSRICGHLLIGAAKNSFAKLMDKISLAMDTMPLHNNRSITYVEKDSLVQRLARGLHKVNTLALKYGLQGHVPILKSTASLQKQIFGFTQRLHAAEVERRSLRLEVTELKRNLNEMKKELDKTQGLQMQLNEFKQSKLITHEKFESACEELNNALLREQQAQMLLNEQAQQLQELNYRLELHSSEEADKNQTLGEAVKSLSEAKMELRRKDQSLRQLNRHLTQLEQDKRRLEENIHDAESALRMAAKDKECVANHMRTVENMLHKVRDQISLSRTAASRNDFTLQLPRLHLETFAMEGLKGGPEVVACQAMIKSFVDVYQLASARIATLEKEMTSHRSHIATLKSELHTACLRENASLQSTGSRDHSNLSIPSRAALPADTTDVGDFLPLKAELDTTYTFLKETLINSVPLASSSNSSPVTMSATAKRPAQIGL", "length": 1334, "header": "tr|G3MX83-1|G3MX83_BOVIN Isoform 1 of Coiled-coil domain containing 171 OS=Bos taurus OX=9913 GN=CCDC171 PE=4 SV=3 CANONICAL=G3MX83-1" }, "locus": { "chromosome": "8", "start_pos": 28764493, "end_pos": 28433127, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000065456.3", "url": "https://www.ensembl.org/id/ENSBTAT00000065456.3" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000054143.3", "url": "https://www.ensembl.org/id/ENSBTAP00000054143.3" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [ { "id": "bta:538331", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?bta:538331", "resource": "KEGG Pathway" } ], "orthologs": [], "go_annotation": {}, "pro_annotation": [], "site_annotation": [ { "start_pos": 1090, "end_pos": 1092, "annotation": "n_glycosylation_sequon" }, { "start_pos": 1255, "end_pos": 1257, "annotation": "n_glycosylation_sequon" }, { "start_pos": 1268, "end_pos": 1270, "annotation": "n_glycosylation_sequon" }, { "start_pos": 1316, "end_pos": 1318, "annotation": "n_glycosylation_sequon" }, { "start_pos": 18, "end_pos": 20, "annotation": "n_glycosylation_sequon" }, { "start_pos": 4, "end_pos": 6, "annotation": "n_glycosylation_sequon" }, { "start_pos": 639, "end_pos": 641, "annotation": "n_glycosylation_sequon" }, { "start_pos": 937, "end_pos": 939, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 1090, "end_pos": 1092 }, { "start_pos": 1255, "end_pos": 1257 }, { "start_pos": 1268, "end_pos": 1270 }, { "start_pos": 1316, "end_pos": 1318 }, { "start_pos": 18, "end_pos": 20 }, { "start_pos": 4, "end_pos": 6 }, { "start_pos": 639, "end_pos": 641 }, { "start_pos": 937, "end_pos": 939 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { 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"database": "Ensembl Transcript", "id": "ENSBTAT00000004647.6", "url": "https://www.ensembl.org/id/ENSBTAT00000004647.6" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000004647.4", "url": "https://www.ensembl.org/id/ENSBTAP00000004647.4" } ] } }, { "isoform_ac": "G3MZN0-1", "url": "https://www.uniprot.org/uniprotkb/G3MZN0/entry", "sequence": { "sequence": "MLVITASGNQCPGLGRSDLACGHTVGSARRIDASQTMTSCGQQPLNVLAVLSLLISAVLSAHFRVCEPYTDHKGRYHFGFHCPRLSDNKTFILCCHHNNTVFKYCCNETEFQAVMQANLTAGSEGYMHNNYTALLGVWIYGFFVLMLLVLDLLYYSAMNYDICKVYLARWGIHGRWMKQDPRRWGNPARAPRPGQPAPQPQPPPGPLPQAPQAVHTLQRDSHTPPLMTFQSSSA", "length": 234, "header": "tr|G3MZN0-1|G3MZN0_BOVIN Isoform 1 of Shisa like 1 OS=Bos taurus OX=9913 GN=SHISAL1 PE=4 SV=3 CANONICAL=G3MZN0-1" }, "locus": { "chromosome": "5", "start_pos": 115014752, "end_pos": 114969553, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000064701.3", "url": "https://www.ensembl.org/id/ENSBTAT00000064701.3" }, { "database": "Ensembl 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"InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR056266", "url": "https://www.ebi.ac.uk/interpro/entry/IPR056266", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR056268", "url": "https://www.ebi.ac.uk/interpro/entry/IPR056268", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR056269", "url": "https://www.ebi.ac.uk/interpro/entry/IPR056269", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR056965", "url": "https://www.ebi.ac.uk/interpro/entry/IPR056965", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "bta:540622", "url": "https://www.genome.jp/dbget-bin/www_bget?bta:540622", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "IACETGR", "url": "https://omabrowser.org/oma/group/IACETGR/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "F1MXD2", "url": "https://www.orthodb.org/?gene=F1MXD2", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "G3N093", "url": "https://www.orthodb.org/?gene=G3N093", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR14477", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR14477", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR14477:SF1", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR14477:SF1", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF23665", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF23665", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF23667", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF23667", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF23668", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF23668", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF25142", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF25142", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "XP_002697164", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_002697164", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "F1MXD2", "url": "https://www.uniprot.org/uniprotkb/F1MXD2", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "F1MXD2-1", "url": "https://www.uniprot.org/uniprotkb/F1MXD2-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "G3N093", "url": "https://www.uniprot.org/uniprotkb/G3N093", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "G3N093-1", "url": "https://www.uniprot.org/uniprotkb/G3N093-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MASLNCGVAVALLGILLLGAARLPRGVAYEIDLPRGSGITVLLKPATQALPVKLCYIMSKRWETTLSIKAGEKKVFSFSCQDPHNYFVIEIQKNIDCVSGQCPFGEVYLQPSTSVLPTLNRTFIWDIKASKNVSLELQFSLSRLRQIGLTENCPDGVTHRISGRVDASTMVRIGTFCGNGTVSRIKMQEGVNLALDLPWFHSRNVSGFSIANRSSIKRLCIIESVFEGEGSATLMSANYPAGFPEDELMTWQFVIPAPLRASVSFLQFNVSNCVKKEERVEYYIPGSTTNPEVFKLEDQQPGNMAGNFNLSLQGCDQDAQNPGILRLQFQVSVQHPQNDSNKTYVVDLSKERTMSLSIEPRPNKLKREFVPSCFVCLNSRTCSTNLTLTAGSKHTISFLCDDLTRLWINAEKTISCLDHRYCHRMRYSLQLPPSVFQLPVQLHDFTWKLLVPKDRLSLALVPAQKLQQHTHERVCNTSFSYLVASAVPGQNLYFGSFCSGGSIEQIQVKENISVTLRTFAPNFQHESAKQDLTVSFIPHFKEESVFTVTPDTKNKVYLRTPNWDRGLPSLASVSWNISVPRNQVACLTFLKERTGVVCQTGRAFMIIQEQRAHAEEIFSLEEEVLPKPSFRYHSFWVNISNCSPMSGKQLDLLFWVSLTPRTTDLTVIILTVVGGGALLLFALGFIICFVKKNKKKKITKGPAVGIYNGNVNTQMPMQRKKFQKGRKDNDSHVYAVIDDTMVYGHLLQDASGPFIQAEVDTYRPFQGPTGDFPPSPPPTNSKAPTVKLATDEPPPGSPSESESEPYTFSHPKDGKVSNRSTDTPLLDAHEPTEPGE", "length": 836, "header": "tr|G3N093-1|G3N093_BOVIN Isoform 1 of CUB domain containing protein 1 OS=Bos taurus OX=9913 GN=CDCP1 PE=4 SV=1 CANONICAL=G3N093-1" }, "isoforms": [ { "isoform_ac": "F1MXD2-1", "url": "https://www.uniprot.org/uniprotkb/F1MXD2/entry", "sequence": { "sequence": "MASLNCGVAVALLGILLLGAARLPRGVAYEIDLPRGSGITVLLKPATQALPVKLCYIMSKRWETTLSIKAGEKKVFSFSCQDPHNYFVIEIQKNIDCVSGQCPFGEVYLQPSTSVLPTLNRTFIWDIKASKNVSLELQFSLSRLRQIGLTENCPDGVTHRISGRVDASTMVRIGTFCGNGTVSRIKMQEGVNLALDLPWFHSRNVSGFSIANRSSIKRLCIIESVFEGEGSATLMSANYPAGFPEDELMTWQFVIPAPLRASVSFLQFNVSNCVKKEERVEYYIPGSTTNPEVFKLEDQQPGNMAGNFNLSLQGCDQDAQNPGILRLQFQVSVQHPQNDSSCLDHRYCHRMRYSLQLPPSVFQLPVQLHDFTWKLLVPKDRLSLALVPAQKLQQHTHERVCNTSFSYLVASAVPGQNLYFGSFCSGGSIEQIQVKENISVTLRTFAPNFQHESAKQDLTVSFIPHFKEESVFTVTPDTKNKVYLRTPNWDRGLPSLASVSWNISVPRNQVACLTFLKERTGVVCQTGRAFMIIQEQRAHAEEIFSLEEEVLPKPSFRYHSFWVNISNCSPMSGKQLDLLFWVSLTPRTTDLTVIILTVVGGGALLLFALGFIICFVKKNKKKKITKGPAVGIYNGNVNTQMPMQRKKFQKGRKDNDSHVYAVIDDTMVYGHLLQDASGPFIQAEVDTYRPFQGPTGDFPPSPPPTNSKAPTVKLATDEPPPGSPSESESEPYTFSHPKDGKVSNRSTDTPLLDAHEPTEPGE", "length": 762, "header": "tr|F1MXD2-1|G3N093_BOVIN Computationally mapped isoform of CUB domain containing protein 1 OS=Bos taurus OX=9913 GN=CDCP1 PE=4 SV=4 CANONICAL=G3N093-1" }, "locus": { "chromosome": "22", "start_pos": 54138904, "end_pos": 54085716, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000016560.8", "url": "https://www.ensembl.org/id/ENSBTAT00000016560.8" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000016560.7", "url": "https://www.ensembl.org/id/ENSBTAP00000016560.7" } ] } }, { "isoform_ac": "G3N093-1", "url": "https://www.uniprot.org/uniprotkb/G3N093/entry", "sequence": { "sequence": "MASLNCGVAVALLGILLLGAARLPRGVAYEIDLPRGSGITVLLKPATQALPVKLCYIMSKRWETTLSIKAGEKKVFSFSCQDPHNYFVIEIQKNIDCVSGQCPFGEVYLQPSTSVLPTLNRTFIWDIKASKNVSLELQFSLSRLRQIGLTENCPDGVTHRISGRVDASTMVRIGTFCGNGTVSRIKMQEGVNLALDLPWFHSRNVSGFSIANRSSIKRLCIIESVFEGEGSATLMSANYPAGFPEDELMTWQFVIPAPLRASVSFLQFNVSNCVKKEERVEYYIPGSTTNPEVFKLEDQQPGNMAGNFNLSLQGCDQDAQNPGILRLQFQVSVQHPQNDSNKTYVVDLSKERTMSLSIEPRPNKLKREFVPSCFVCLNSRTCSTNLTLTAGSKHTISFLCDDLTRLWINAEKTISCLDHRYCHRMRYSLQLPPSVFQLPVQLHDFTWKLLVPKDRLSLALVPAQKLQQHTHERVCNTSFSYLVASAVPGQNLYFGSFCSGGSIEQIQVKENISVTLRTFAPNFQHESAKQDLTVSFIPHFKEESVFTVTPDTKNKVYLRTPNWDRGLPSLASVSWNISVPRNQVACLTFLKERTGVVCQTGRAFMIIQEQRAHAEEIFSLEEEVLPKPSFRYHSFWVNISNCSPMSGKQLDLLFWVSLTPRTTDLTVIILTVVGGGALLLFALGFIICFVKKNKKKKITKGPAVGIYNGNVNTQMPMQRKKFQKGRKDNDSHVYAVIDDTMVYGHLLQDASGPFIQAEVDTYRPFQGPTGDFPPSPPPTNSKAPTVKLATDEPPPGSPSESESEPYTFSHPKDGKVSNRSTDTPLLDAHEPTEPGE", "length": 836, "header": "tr|G3N093-1|G3N093_BOVIN Isoform 1 of CUB domain containing protein 1 OS=Bos taurus OX=9913 GN=CDCP1 PE=4 SV=1 CANONICAL=G3N093-1" }, "locus": { "chromosome": "22", "start_pos": 54138904, "end_pos": 54085716, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000065511.4", "url": "https://www.ensembl.org/id/ENSBTAT00000065511.4" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000055250.1", "url": "https://www.ensembl.org/id/ENSBTAP00000055250.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [ { "id": "bta:540622", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?bta:540622", "resource": "KEGG Pathway" } ], "orthologs": [ { "uniprot_canonical_ac": "A0A2R8PY98-1", "protein_name": "CUB domain-containing protein 1", "gene_name": "cdcp1b", "tax_id": 7955, "organism": "Danio rerio", "sequence": { "sequence": "MGSSAVPVLIGLILLHIHKISECQTIEVTPDPSTNVIFSKKPGQGLDCTVCKNEDSSQSCDSSLRLTESKTTSVSFNCSQPGDVFTVEINQDIDCSSSACSSIAVHPDATRFLEFSRSFTWDVKVHSSKMFHLDFPAPGMRQIKPSESCPDQHTYSITSYQRTGPISIGSFCRNGTISRIQVWYRGRISLEVPKGTPLNPSDFRVSIGPASTGLVEVDVKLPRAESSVDFFTPNYGTGYYNAYKVKWNFAVEPIVNFTVEFKAYAPPECQKKEVTVDYALGEKTSFTTKPTDIQPNNKQGDFSLTLNNCDAKSTPKVPGLSMHIMVGVFRGGIPYLCTVDLQNEEGLSLEIVNTNPQSYCEMRSNSVVQEKIVVPVGSKVDLYFLDCPAQDLRLTATKTIDFSGVSARSVSRTPLIIPPMKWSLPVALNEFSWLLRVPDQTTLDLTSAQRNLHQSVPDKPCKEKVSLLVSESLGSSIGQFCSPADGAIQKIQIRGNVSITVSPNTVKDLSQETDPFLNITLSPEITENVIYTVSPLISGPAYLASPYWPDAMQPSSSASWIINVPPEYRANLWFTNVSKPTCDSGHAELEISPLDSSAETQEWREDQSFPDSIVQQTSFYLNMSNCEPASGRYALLTKIIVQKESKKILAIILAVVGAVLALLIVALVVVCVIRKKHKPSGNRSSIYIPKGKPVLPGNATFPKSRTDNESHVYASIDETIYNRHLDTNHPADSNNGTWTNGHQVDTYRPFLGPTDSIPTDQDLPDGYSLDRGRDKDVFQPFLTPPNTFNLPRPRSPLISQGSLGFEDRRMVDNELNTFKAAGDINPIRLSTDECKLRPQMDSDSDSYHEPEYEEAM", "length": 856 }, "evidence": [ { "id": "G3N093", "url": "https://omabrowser.org/oma/group/G3N093/", "database": "OMA" } ], "glygen_name": "Zebrafish", "common_name": "Zebrafish" }, { "uniprot_canonical_ac": "A0A8V0Z218-1", "protein_name": "CUB domain containing protein 1", "gene_name": "CDCP1", "tax_id": 9031, "organism": "Gallus gallus", "sequence": { "sequence": "MAGGRALLAVLAVLIAASAQHLKREASFTISLRAADNITVTIKLKPGVLPACLIRVKSGPRPELKIRPGENVTLSFTCNTPEKYLMMEIQKNIDCVSGPCPFGDVHLYPPGLPRLNRIFIWDVKASTKAGLELKFSAPLRQIQPGEMCPDLVSYNINSCIDKATVNIGTFCRNGSVSRVKLLGGVIMSLHLPWNLTVATSGFNIANRSSIKRLCIIESILKGESSIMLMSPNYPLGFPEDELMTWQFVVPSNMRASVFFHDYSLSNCERKEERVEYYIPGSVSNPEVFKLSDSQPANIAGSFNMSLQGCDQDAQNPGVLRLLFQVIVQHPQIDENVTHLVDLSKERNMTVTIHFEGWPRRTPLVSEPMCLICKDPRTCDRVLTLASGATYKISFLCKDLSHLRITAEKGISCVGLRWCESRIYSLSVPKTITQLPVQLHKFIWKLIAPEEINIEITSPSLKLRQHLPEQNCNTSYSYSIISATPETEMNVGIFCPGGAIEKIQLRNNITISLKTFGKGFLNESNHQDLKMSFVPHIKVQAWSHCLDQSLSESVRWLIPAGRKDSCCRWLRGNSAAMSVIITDTEEMIDECTFTVSPDSKAKTYLQTPNSHYGLPPYVSISWYIIVPSKQVARLGFSTDRMGITCETGRAYVNIKEQMPGAEETVRREDELLPQPRNMHYNFWVNISNCKPVDPMQLSLKFWVTFVEKQIDLAVIVGVLAGFGVLAAIGLTVCCIKKKKKKSQNPMVGVYNTNVNTQMPGKQRLFKKDRKTNESHVYAVIDDAMVYGHLLKESNGSVTPEVDVYQPFDGPMGSLPPSPPPFSFRKDVKHSPNTEEPPLLAETDHDAYTFAHQKSGELEDNGEGNAKNNGDTSMSLLENKERDSLEE", "length": 885 }, "evidence": [ { "id": "G3N093", "url": "https://omabrowser.org/oma/group/G3N093/", "database": "OMA" } ], "glygen_name": "Chicken", "common_name": "Chicken" }, { "uniprot_canonical_ac": "D3ZVA1-1", "protein_name": "CUB domain containing protein 1", "gene_name": "Cdcp1", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MARSACGFSVALLGTLLLGTACLLRGTASEIALPRGSDITVHIKLVSPALPVKFCYIVVSRQHVTELTIRPGERKSFTFSCNNPEKHYVLKIEKNIDCMSGPCPFGEVRLQPSKSELPILNRTYIWDVRAHKSIGLELQFATPRLRQIGPGESCADGVTHSISGHIDATEVRIGTFCSNGTVSRIKMQEGVKMALHLPWFHPRNISGFSIANRSSIKRLCIIESVFEGEGSATLMSANYPGGFPEDELMTWQFVVPAHLRASVSFLNFNVSNCERKEERVEYYIPGSTTNPEVFRLEDQQPGNMAGNFNLSLQGCDQDAQSPGILRLQFQVLVQRPQNESNITYMVDLSQERTMSLTIEPRPVKHGRRFVPGCFVCLDSRTCSTNVTLTAGSKHKISFLCDDLARLWMNVEKTLSCLDHRYYYGKSFNLQVPKDILQLPVQLHDFSWKLLVPKDRLGLMLVPGQKLQQHTRERPCNTSFGYQVASTTPGQDLYFGSFCPGGSIEKIQVKQNSSVTLRTYAPGFQQEVSKQVLTVSLIPYFKEEGIFTVTPDSKNKVYLRSPNWDRGLPALSSVSWNISVPSNQVACLTFFRERSGLACQSGRAFMIIQEQQTRAEEIFSLEEEVLPKPSFHHHSFWVNISNCSPMNGKQLDLLFWVTLTPRTVDLTVIIGAAGGGALLLFALGLIICLVKKKKKVDKGPAVGIYNGNANTQMPQTQKFQKRRKDNDSHVYAVIEDTMVYGHLLQDSGGSFIQAEVDTYRPFQGPMGDCPPTPPPIFSRTPTAKFTADKLAPSSPPESESEPYTFSHPNKGEVGVRDTGIPLLNIQGPMETEE", "length": 832 }, "evidence": [ { "id": "G3N093", "url": "https://omabrowser.org/oma/group/G3N093/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "F1SRD0-1", "protein_name": "CUB domain containing protein 1", "gene_name": "CDCP1", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MAGLNFGVTVAVLGVLLLSASRLSSGVEVYEIALPHGSGITVFIKPGTPTLPMKLCHIISSRRKETTLSIKSGDKIVFYFSCQDPENHFVIEIQKNIDCMAGPCPFGEVQLQPSTSVLPSLNRTFIWDVRAHKNIGLELQFSHPRLRQIGPRESCPDGVSHSISGRIDTSLVRIGTFCRNGTVSRIKMQEGVKMALHLPWFHDRNISGFSIANRSSIKRLCIIESVFEGEGSATLMSANYPDGFPEDELMTWQFIIPAHLRASVSFLHFNVSNCVKKEERVEYYIPGSTTNPEVFKLEDKQPGNMAGNFNLSLQGCDQDAQNPGILRLQFQVLVQRPQDESNKTYVVDLSNEQAMSLTIEPRLSKQSRKFVPGCFVCLDSRTCSTNLTLTSGSKHKISFLCDDLTRLWINAEKTITCMDHRYCHRKSYSLQVPWYILQLPVQLHDFSWKLLVPKDSLSLALVPAQKLQQHTHERACNTSFSYLLASAVPGQELYFGFFCSGGSIEQIQVKQNVSVTLRTFAPNFQQEASRQNLTVSFIPHFKEEGVFTVTPDTKSKVYLRTPNWDRGLPSLTSVSWNISVPRDQVACLTFLKERTGVVCQTGRAFMIIQEQRARAEEIFSLEEEVLPKPSFHHHSFWVNISNCSPASGKQLDLLFWVSLSPRTTDLTVIIIAVVGGGALLLFALGLIICFVKKNRKKKITKGPAVGIYNGNVNTQMPMQPKKFQKRRKDNDSHVYAVIDDTMVYGHLLQDANGSFLQPEVDTYRPFQGPTGDRPPSPPPICSRAPTAKLTTEEPSPGFLPESESEPYAFSHPKDGNISNGNTDTPLLDAHKPTEPGE", "length": 837 }, "evidence": [ { "id": "G3N093", "url": "https://omabrowser.org/oma/group/G3N093/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "G3HP50-1", "protein_name": "CUB domain-containing protein 1", "gene_name": "Cdcp1", "tax_id": 10029, "organism": "Cricetulus griseus", "sequence": { "sequence": "MARSACGFSVALLGALLLGTAHLPHGTEASEISLPHGSGITVRIRLANPALPVKPCHIVMSRQPITELLVKPGERKSFTFNCINPEKHFVLEIEKNIDCMSGPCPFGEVRLQPSTSELPTLNRTFIWDVRAHKSIGLELQFSTPRLRQIGPGERCADGVTHSISGRIDATEVRIGTFCSNGTVSRIKMQEGVKMALHVPWNIPRNISGFSIANRSSIKRLCIIESVFEGEGSATLMSANYPGGFPEDELMTWQFVVPEHLRASVSFLNFNVSNCERKEERVEYYIPGSTTNPEVFRLEDKQPGNMAGNFNLSLQGCDQDAQSPGILRLQFQVLVQRPQNESNKTYVVDLSQERTMSLTIEPRPVKHGRRFVPGCFVCLESRTCSTNVTLTAGTKHKISFLCDDLTRLWVNAEKTLSCLDYYYCYKKSFHLQVPKDILQLPVQLHDFSWKLLVPKDRLGLMLVPGQKLQQHTRERACNTSLGYVIASTTPGQDLYFGSFCPGGSIEKIQVKQNSSVTLRTYAPSSQQEVSRQGLTVSFIPYFKEEGIFTVTPDTKNKVYLRTPSWDRGLPALSSVSWNISVPSNQVACLTFFKERSGVVCQSGRAYMIIQEQQTRAEEVFSLEEEVLPKPSFHHHSFWVNISNCSPMNGKQLDLLFWVTLTPRTVDLAVIIGAAGGGALLLFALGLIICFVRKKKKINKGPAVGIYNGNVNTQIPQIQNFQKRRKDNDSHVYAVIDDTMVYGHLLQDSGGSFIQPEVDTYRPFQGPMGDCPPSPPPVFSRTPTAKFTADEPAPNSPPESESEPYTFSHPNKGEVGVRETDIPLLNIQGPVETEE", "length": 833 }, "evidence": [ { "id": "G3N093", "url": "https://omabrowser.org/oma/group/G3N093/", "database": "OMA" } ], "glygen_name": "Hamster", "common_name": "Chinese hamster" }, { "uniprot_canonical_ac": "Q5U462-1", "protein_name": "CUB domain-containing protein 1", "gene_name": "Cdcp1", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MAHSACGFSVALLGALLLGTARLLRGTEASEIALPQRSGVTVSIKLGNPALPVKICYIVMSRQHITELIIRPGERKSFTFSCSNPEKHFVLKIEKNIDCMSGPCPFGEVHLQPSTSELPILNRTFIWDVRAHKSIGLELQFATPRLRQIGPGESCADGVTHSISGHIDATEVRIGTFCSNGTVSRIKMQEGVKMALHLPWFHRRNVSGFSIANRSSIKRLCIIESVFEGEGSATLMSANYPGGFPEDELMTWQFVVPAHLRASVSFLNFNVSNCERKEERVEYYIPGSTTNPEVFRLEDKQPGNMAGNFNLSLQGCDQDAQSPGILRLQFQVLVQRPQDESNKTYMVDLSRERTMSLTIEPRPVKHGRRFVPGCFVCLESRTCSTNVTLTAGSIHKISFLCDDLTRLWVNVEKTLSCLDHRYCYRQSFKLQVPDYILQLPVQLHDFSWKLLVPKDKLSLMLVPGQKLQQHTQERPCNTSFGYHVTSTTPGQDLYFGSFCSGGSIEKIQVKQNSSVTLRAYAPSFQQEVSKQGLIVSYTPYFKEEGIFTVTPDTKNKVYLRSPNWDRGLPALSSVSWNISVPSNQVACLTVLKERSGLACQSGRAFMIIQEQQSRAEEIFSLEEEVLPKPSFHHHSFWVNISNCSPMNGKQLDLLFWVTLTPRTVDLAVVIGAAGGGALLLFALVLIICFVKKKKKVDKGPAVGIYNGNVNTQMPQTQKFPKGRKDNDSHVYAVIEDTMVYGHLLQDSGGSFIQPEVDTYRPFQGPMGDCPPTPPPLFSRTPTAKFTAEELAPSSPPESESEPYTFSHPNKGEIGVRETDIPLLHTQGPVETEE", "length": 833 }, "evidence": [ { "id": "G3N093", "url": "https://omabrowser.org/oma/group/G3N093/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q9H5V8-1", "protein_name": "CUB domain-containing protein 1", "gene_name": "CDCP1", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MAGLNCGVSIALLGVLLLGAARLPRGAEAFEIALPRESNITVLIKLGTPTLLAKPCYIVISKRHITMLSIKSGERIVFTFSCQSPENHFVIEIQKNIDCMSGPCPFGEVQLQPSTSLLPTLNRTFIWDVKAHKSIGLELQFSIPRLRQIGPGESCPDGVTHSISGRIDATVVRIGTFCSNGTVSRIKMQEGVKMALHLPWFHPRNVSGFSIANRSSIKRLCIIESVFEGEGSATLMSANYPEGFPEDELMTWQFVVPAHLRASVSFLNFNLSNCERKEERVEYYIPGSTTNPEVFKLEDKQPGNMAGNFNLSLQGCDQDAQSPGILRLQFQVLVQHPQNESNKIYVVDLSNERAMSLTIEPRPVKQSRKFVPGCFVCLESRTCSSNLTLTSGSKHKISFLCDDLTRLWMNVEKTISCTDHRYCQRKSYSLQVPSDILHLPVELHDFSWKLLVPKDRLSLVLVPAQKLQQHTHEKPCNTSFSYLVASAIPSQDLYFGSFCPGGSIKQIQVKQNISVTLRTFAPSFQQEASRQGLTVSFIPYFKEEGVFTVTPDTKSKVYLRTPNWDRGLPSLTSVSWNISVPRDQVACLTFFKERSGVVCQTGRAFMIIQEQRTRAEEIFSLDEDVLPKPSFHHHSFWVNISNCSPTSGKQLDLLFSVTLTPRTVDLTVILIAAVGGGVLLLSALGLIICCVKKKKKKTNKGPAVGIYNDNINTEMPRQPKKFQKGRKDNDSHVYAVIEDTMVYGHLLQDSSGSFLQPEVDTYRPFQGTMGVCPPSPPTICSRAPTAKLATEEPPPRSPPESESEPYTFSHPNNGDVSSKDTDIPLLNTQEPMEPAE", "length": 836 }, "evidence": [ { "id": "G3N093", "url": "https://omabrowser.org/oma/group/G3N093/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" } ], "go_annotation": {}, "pro_annotation": [], "site_annotation": [ { "start_pos": 120, "end_pos": 122, "annotation": "n_glycosylation_sequon" }, { "start_pos": 132, "end_pos": 134, "annotation": "n_glycosylation_sequon" }, { "start_pos": 179, "end_pos": 181, "annotation": "n_glycosylation_sequon" }, { "start_pos": 204, "end_pos": 206, "annotation": "n_glycosylation_sequon" }, { "start_pos": 212, "end_pos": 214, "annotation": "n_glycosylation_sequon" }, { "start_pos": 269, "end_pos": 271, "annotation": "n_glycosylation_sequon" }, { "start_pos": 309, "end_pos": 311, "annotation": "n_glycosylation_sequon" }, { "start_pos": 338, "end_pos": 340, "annotation": "n_glycosylation_sequon" }, { "start_pos": 341, "end_pos": 343, "annotation": "n_glycosylation_sequon" }, { "start_pos": 385, "end_pos": 387, "annotation": "n_glycosylation_sequon" }, { "start_pos": 476, "end_pos": 478, "annotation": "n_glycosylation_sequon" }, { "start_pos": 511, "end_pos": 513, "annotation": 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"https://www.uniprot.org/uniprotkb/G3N093" }, { "id": "PF23667", "database": "Pfam", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF23667" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "CDCP1 first CUB", "eco_id": "ECO_0000259", "start_pos": 30, "end_pos": 97, "start_aa": "Glu", "end_aa": "Cys", "glycosite_overlap": [] }, { "evidence": [ { "id": "G3N093", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3N093" }, { "id": "PF25142", "database": "Pfam", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF25142" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "CDCP1 fourth CUB", "eco_id": "ECO_0000259", "start_pos": 344, "end_pos": 430, "start_aa": "Tyr", "end_aa": "Gln", "glycosite_overlap": [] }, { "evidence": [ { "id": "G3N093", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3N093" }, { "id": "PF23668", "database": "Pfam", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF23668" } ], "ann_type": 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"url": "https://www.ebi.ac.uk/interpro/entry/IPR011029", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR027417", "url": "https://www.ebi.ac.uk/interpro/entry/IPR027417", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR032675", "url": "https://www.ebi.ac.uk/interpro/entry/IPR032675", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR041075", "url": "https://www.ebi.ac.uk/interpro/entry/IPR041075", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR041267", "url": "https://www.ebi.ac.uk/interpro/entry/IPR041267", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR050637", "url": "https://www.ebi.ac.uk/interpro/entry/IPR050637", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "F1MZG0", "url": "https://www.orthodb.org/?gene=F1MZG0", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "G3MYV6", "url": "https://www.orthodb.org/?gene=G3MYV6", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR45690", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR45690", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR45690:SF16", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR45690:SF16", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF02758", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF02758", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF05729", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF05729", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF13516", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF13516", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF17776", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF17776", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF17779", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF17779", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "A0AAA9SI33", "url": "https://www.uniprot.org/uniprotkb/A0AAA9SI33", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0AAA9SI33-1", "url": "https://www.uniprot.org/uniprotkb/A0AAA9SI33-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "F1MZG0", "url": "https://www.uniprot.org/uniprotkb/F1MZG0", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "F1MZG0-1", "url": "https://www.uniprot.org/uniprotkb/F1MZG0-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "G3MYV6", "url": "https://www.uniprot.org/uniprotkb/G3MYV6", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "G3MYV6-1", "url": "https://www.uniprot.org/uniprotkb/G3MYV6-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MASPAGISWHDGARDQLLSHLRGLDPWQLEDFKLALQCPELLPEGARRIPWADLRAAGPADLLCLLEERFPGRRTWEAALRVFEDLRLSSLCERMRAELHEMSQVCRLQDPNQEEPETLEETAHRRRYRERLRTRILALWDRTPWPEDHIYLRHVTQREHAELRGLLRPRGAGAPPLTMLLEGAAGVGKTTLATKLVLHWAEGVLFRGRFSYVFYISGHWLAKLGDISFAGLLALDWPDSQVPVEEFRAHPERLLFVIDGAEEVTLGSKGSASRPGADWYQELPAASILVRLLKKELVPEATLLVTAGPPGGRALRGLLLRPCRVDIPGFTEGDRREYLRRFLGDPDVAEEAWRRMQGSETLVRLCAAPLACWAVCAGLKRQLAGSPAPAPGAPTPTGLYAQLFCSLLAGAEPGLRTGSSAGQWRAFCSLAAEGLWLAAFTFAGDALERWRLEAPFIDGLLRLQILRRVSDCEHCVTFAHRSFQEFFGALFYVLWGAQGSLGGVPRHQEMRRWLNHAFADANPYWRQMVRFFFGLLGTDLARQLEEAVGCRMSPGVADEVLDWAEELERCGAVSGRFDFLWLFQCLHETQDENLARRVLNRLPVADLDIQGCEHLRVSSFCLKHCQKLRKLRLSVSHRVLEKKRTSGLGTPEMRVADFRMHQWEDICSVFCSGNLSELDLSNSKLSTASMMRLCLKLGNPRCRLQKLAWKSMAPVEGLRKLGLLLRGDRHLTHLDLSSNSLDAAVSRGVFRMLGHSACGLKYLWLESCGLSTEVCHQLFTELGRNSSLSFLSLADNNLSHVELERLREPPGTATCALKELSLEKGNLSAAACEDLASLLTSTPRLTRLCLGLNPLGDEGVQLLCGSLTRPECVLQRLELWCCRLSTPSCRHLSDALLRSRSLTHLNLRRNSLGDGGVKLLSSALGRADCALQSLNLSHCSLTVAGCRELAHALKHNGHLKILDVGNNDIQDEGVKELCSVLKTPSCVLQTLGLEKCSLTAACCRPLSSVLGSSKSLENLNLLGNNLGPDGVSRLWMPLRKPTCKLRKLGLEKDLCSVVSAELEKLHEKGCFLRVKSQWDFNDPEERWWW", "length": 1089, "header": "tr|G3MYV6-1|G3MYV6_BOVIN Isoform 1 of NLR family pyrin domain containing 13 OS=Bos taurus OX=9913 GN=NLRP13 PE=3 SV=3 CANONICAL=G3MYV6-1" }, "isoforms": [ { "isoform_ac": "A0AAA9SI33-1", "url": "https://www.uniprot.org/uniprotkb/A0AAA9SI33/entry", "sequence": { "sequence": 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"length": 1085, "header": "tr|A0AAA9SI33-1|G3MYV6_BOVIN Computationally mapped isoform of NLR family pyrin domain containing 13 OS=Bos taurus OX=9913 GN=NLRP13 PE=3 SV=1 CANONICAL=G3MYV6-1" }, "locus": { "chromosome": "18", "start_pos": 63449560, "end_pos": 63416914, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000106370.1", "url": "https://www.ensembl.org/id/ENSBTAT00000106370.1" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000082201.1", "url": "https://www.ensembl.org/id/ENSBTAP00000082201.1" } ] } }, { "isoform_ac": "F1MZG0-1", "url": "https://www.uniprot.org/uniprotkb/F1MZG0/entry", "sequence": { "sequence": "MASPAGISWHDGARDQLLSHLRGLDPWQLEDFKLALQCPELLPEGARRIPWADLRAAGPADLLCLLEERFPGRRTWEAALRVFEDLRLSSLCERMRAELHEMSQVCRLQDPNQEEPETLEETAHRRRYRERLRTRILALWDRTPWPEDHIYLRHVTQREHAELRGLLRPRGAGAPPLTMLLEGAAGVGKTTLATKLVLHWAEGVLFRGRFSYVFYISGHWLAKLGDISFAGLLALDWPDSQVPVEEFRAHPERLLFVIDGAEEVTLGSKGSASRPGADWYQELPAASILVRLLKKELVPEATLLVTAGPPGGRALRGLLLRPCRVDIPGFTEGDRREYLRRFLGDPDVAEEAWRRMQGSETLVRLCAAPLACWAVCAGLKRQLAGSPAPAPGAPTPTGLYAQLFCSLLAGAEPGLRTGSSAGQWRAFCSLAAEGLWLAAFTFAGDALERWRLEAPFIDGLLRLQILRRVSDCEHCVTFAHRSFQEFFGALFYVLWGAQGSLGGVPRHQEMRRWLNHAFADANPYWRQMVRFFFGLLGTDLARQLEEAVGCRMSPGVADEVLDWAEELERCGAVSGRFDFLWLFQCLHETQDENLARRVLNRLPVADLDIQGCEHLRVSSFCLKHCQKLRKLRLSVSHRVLEKKRTSGLGTPEMRVADFRMHQWEDICSVFCSGNLSELDLSNSKLSTASMMRLCLKLGNPRCRLQKLAWKSMAPVEGLRKLGLLLRGDRHLTHLDLSSNSLDAAVSRGVFRMLGHSACGLKYLWLESCGLSTEVCHQLFTELGRNSSLSFLSLADNNLSHVELERLREPPGTATCALKELSLEKGNLSAAACEDLASLLTSTPRLTRLCLGLNPLGDEGVQLLCGSLTRPECVLQRLELWCCRLSTPSCRHLSDALLRSRSLTHLNLRRNSLGDGGVKLLSSALGRADCALQSLNLSHCSLTVAGCRELAHALKHNGHLKILDVGNNDIQDEGVKELCSVLKTPSCVLQTLGLEKCSLTAACCRPLSSVLGSSKSLENLNLLGNNLGPDGVSRLWMPLRKPTCKLRKLGAFSFLGRFGPAKLPASRVVVCIHIVQ", "length": 1075, "header": "tr|F1MZG0-1|G3MYV6_BOVIN Computationally mapped isoform of NLR family pyrin domain containing 13 OS=Bos taurus OX=9913 GN=NLRP13 PE=3 SV=4 CANONICAL=G3MYV6-1" }, "locus": { "chromosome": "18", "start_pos": 63449560, "end_pos": 63423088, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000030343.5", "url": "https://www.ensembl.org/id/ENSBTAT00000030343.5" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000030327.5", "url": "https://www.ensembl.org/id/ENSBTAP00000030327.5" } ] } }, { "isoform_ac": "G3MYV6-1", "url": "https://www.uniprot.org/uniprotkb/G3MYV6/entry", "sequence": { "sequence": "MASPAGISWHDGARDQLLSHLRGLDPWQLEDFKLALQCPELLPEGARRIPWADLRAAGPADLLCLLEERFPGRRTWEAALRVFEDLRLSSLCERMRAELHEMSQVCRLQDPNQEEPETLEETAHRRRYRERLRTRILALWDRTPWPEDHIYLRHVTQREHAELRGLLRPRGAGAPPLTMLLEGAAGVGKTTLATKLVLHWAEGVLFRGRFSYVFYISGHWLAKLGDISFAGLLALDWPDSQVPVEEFRAHPERLLFVIDGAEEVTLGSKGSASRPGADWYQELPAASILVRLLKKELVPEATLLVTAGPPGGRALRGLLLRPCRVDIPGFTEGDRREYLRRFLGDPDVAEEAWRRMQGSETLVRLCAAPLACWAVCAGLKRQLAGSPAPAPGAPTPTGLYAQLFCSLLAGAEPGLRTGSSAGQWRAFCSLAAEGLWLAAFTFAGDALERWRLEAPFIDGLLRLQILRRVSDCEHCVTFAHRSFQEFFGALFYVLWGAQGSLGGVPRHQEMRRWLNHAFADANPYWRQMVRFFFGLLGTDLARQLEEAVGCRMSPGVADEVLDWAEELERCGAVSGRFDFLWLFQCLHETQDENLARRVLNRLPVADLDIQGCEHLRVSSFCLKHCQKLRKLRLSVSHRVLEKKRTSGLGTPEMRVADFRMHQWEDICSVFCSGNLSELDLSNSKLSTASMMRLCLKLGNPRCRLQKLAWKSMAPVEGLRKLGLLLRGDRHLTHLDLSSNSLDAAVSRGVFRMLGHSACGLKYLWLESCGLSTEVCHQLFTELGRNSSLSFLSLADNNLSHVELERLREPPGTATCALKELSLEKGNLSAAACEDLASLLTSTPRLTRLCLGLNPLGDEGVQLLCGSLTRPECVLQRLELWCCRLSTPSCRHLSDALLRSRSLTHLNLRRNSLGDGGVKLLSSALGRADCALQSLNLSHCSLTVAGCRELAHALKHNGHLKILDVGNNDIQDEGVKELCSVLKTPSCVLQTLGLEKCSLTAACCRPLSSVLGSSKSLENLNLLGNNLGPDGVSRLWMPLRKPTCKLRKLGLEKDLCSVVSAELEKLHEKGCFLRVKSQWDFNDPEERWWW", "length": 1089, "header": "tr|G3MYV6-1|G3MYV6_BOVIN Isoform 1 of NLR family pyrin domain containing 13 OS=Bos taurus OX=9913 GN=NLRP13 PE=3 SV=3 CANONICAL=G3MYV6-1" }, "locus": { "chromosome": "18", "start_pos": 63449560, "end_pos": 63421029, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000066236.3", "url": "https://www.ensembl.org/id/ENSBTAT00000066236.3" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000054745.3", "url": "https://www.ensembl.org/id/ENSBTAP00000054745.3" } ] } } ], "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "other", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 395, "start_aa": "Thr", "end_pos": 395, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr395", "evidence": [ { "id": "", "database": "GlyGen", "url": "https://data.glygen.org/" } ], "filter_code": "000000000000000010000.00000000001000.0.01000" } ], "phosphorylation": [], "glycation": [], "keywords": [ "glycoprotein", "glycoprotein_predicted" ], "publication": [], "pathway": [], "orthologs": [], "go_annotation": { "categories": [ { "name": "Molecular Function", "total": 1, "go_terms": [ { "name": "ATP binding", "id": "GO:0005524", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005524", "evidence": [ { "database": "UniProtKB", "id": "G3MYV6", "url": "https://www.uniprot.org/uniprotkb/G3MYV6" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 1, "go_terms": [ { "name": "cytoplasm", "id": "GO:0005737", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005737", "evidence": [ { "database": "UniProtKB", "id": "G3MYV6", "url": "https://www.uniprot.org/uniprotkb/G3MYV6" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 1, "go_terms": [ { "name": "regulation of inflammatory response", "id": "GO:0050727", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0050727", "evidence": [ { "database": "UniProtKB", "id": "G3MYV6", "url": "https://www.uniprot.org/uniprotkb/G3MYV6" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 674, "end_pos": 676, "annotation": "n_glycosylation_sequon" }, { "start_pos": 785, "end_pos": 787, "annotation": "n_glycosylation_sequon" }, { "start_pos": 797, "end_pos": 799, "annotation": "n_glycosylation_sequon" }, { "start_pos": 826, "end_pos": 828, "annotation": "n_glycosylation_sequon" }, { "start_pos": 935, "end_pos": 937, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [ { "pdb_id": "AF-G3MYV6-F1", "pdb_chain": "global", "start_pos": 1, "end_pos": 1089, "overlap": "1.0", "method": "AlphaFold", "type": "alphafold", "resolution": -1.0, "url": "https://data.glygen.org/ln2downloads/pdb/current/AF-G3MYV6-F1.pdb", "url_external": "https://alphafold.ebi.ac.uk/entry/G3MYV6" } ], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "G3MYV6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3MYV6" }, { "id": "PS50837", "database": "PROSITE", "url": "https://prosite.expasy.org/PS50837" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "NACHT", "eco_id": "ECO_0000259", "start_pos": 177, "end_pos": 377, "start_aa": "Leu", "end_aa": "Ala", "glycosite_overlap": [] }, { "evidence": [ { "id": "G3MYV6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3MYV6" }, { "id": "PS50824", "database": "PROSITE", "url": "https://prosite.expasy.org/PS50824" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "Pyrin", "eco_id": "ECO_0000259", "start_pos": 1, "end_pos": 101, "start_aa": "Met", "end_aa": "Glu", "glycosite_overlap": [] } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [ 395 ], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 674, "end_pos": 676 }, { "start_pos": 785, "end_pos": 787 }, { "start_pos": 797, "end_pos": 799 }, { "start_pos": 826, "end_pos": 828 }, { "start_pos": 935, "end_pos": 937 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 1 }, { "field": "total_sites", "count": 1 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 1 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "exact_sites", "count": 1 }, { "field": "exact_o_linked_sites", "count": 1 }, { "field": "fuzzy_sites", "count": 0 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_pos", "start_aa", "end_pos", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 1 }, { "field": "total_sites", "count": 1 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 1 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "exact_sites", "count": 1 }, { "field": "exact_o_linked_sites", "count": 1 }, { "field": "fuzzy_sites", "count": 0 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_pos", "start_aa", "end_pos", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": 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"table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ], "tool_support": { "graph_view": "yes" } }, { "uniprot_canonical_ac": "F6RUC4-1", "uniprot_ac": "F6RUC4", "uniprot_id": "F6RUC4_BOVIN", "mass": { "chemical_mass": 50329.0, "monoisotopic_mass": 50329.0 }, "refseq": {}, "gene_names": [ { "name": "TFDP2", "type": "recommended", "evidence": [ { "id": "F6RUC4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F6RUC4" } ] } ], "protein_names": [ { "name": "Transcription factor Dp-2", "type": "synonym", "evidence": [ { "id": "F6RUC4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F6RUC4/entry#names_and_taxonomy" } ] } ], "function": [], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Bos taurus", "taxid": 9913, "evidence": [ { "database": "UniProtKB", "id": "F6RUC4", "url": "https://www.uniprot.org/uniprotkb/F6RUC4" } ], "common_name": "Bovine", "glygen_name": "Bovine", "reference_species": "Bos taurus [9913]" } ], "gene": [ { "name": "TFDP2", "url": "https://www.uniprot.org/uniprotkb/F6RUC4", "locus": { "chromosome": "1", "start_pos": 127026634, "end_pos": 126826185, "strand": "-", "evidence": [ { "database": "Ensembl Gene", "id": "ENSBTAG00000006222", "url": "https://www.ensembl.org/id/ENSBTAG00000006222" } ] } } ], "crossref": [ { "id": "F6RUC4", "url": "https://alphafold.ebi.ac.uk/entry/F6RUC4", "database": "AlphaFoldDB", "categories": [] }, { "id": "ENSBTAG00000006222", "url": "https://bgee.org/?page=gene&gene_id=ENSBTAG00000006222", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "cd14458", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd14458", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "506114", "url": "https://www.ncbi.nlm.nih.gov/gene/506114", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR003316", "url": "https://www.ebi.ac.uk/interpro/entry/IPR003316", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR014889", "url": "https://www.ebi.ac.uk/interpro/entry/IPR014889", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR015648", "url": "https://www.ebi.ac.uk/interpro/entry/IPR015648", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR036388", "url": "https://www.ebi.ac.uk/interpro/entry/IPR036388", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR036390", "url": "https://www.ebi.ac.uk/interpro/entry/IPR036390", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR037241", "url": "https://www.ebi.ac.uk/interpro/entry/IPR037241", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR038168", "url": "https://www.ebi.ac.uk/interpro/entry/IPR038168", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "PTHR12548", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR12548", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR12548:SF5", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR12548:SF5", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF02319", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF02319", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF08781", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF08781", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "A0A3Q1MRQ6", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1MRQ6", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A3Q1MRQ6-1", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1MRQ6-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0AAA9RY78", "url": "https://www.uniprot.org/uniprotkb/A0AAA9RY78", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0AAA9RY78-1", "url": "https://www.uniprot.org/uniprotkb/A0AAA9RY78-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0AAA9S749", "url": "https://www.uniprot.org/uniprotkb/A0AAA9S749", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0AAA9S749-1", "url": "https://www.uniprot.org/uniprotkb/A0AAA9S749-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0AAA9TBJ5", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TBJ5", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0AAA9TBJ5-1", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TBJ5-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0ABI0P4B0", "url": "https://www.uniprot.org/uniprotkb/A0ABI0P4B0", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0ABI0P4B0-1", "url": "https://www.uniprot.org/uniprotkb/A0ABI0P4B0-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0ABI0P516", "url": "https://www.uniprot.org/uniprotkb/A0ABI0P516", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0ABI0P516-1", "url": "https://www.uniprot.org/uniprotkb/A0ABI0P516-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "F6RUC4", "url": "https://www.uniprot.org/uniprotkb/F6RUC4", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "F6RUC4-1", "url": "https://www.uniprot.org/uniprotkb/F6RUC4-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MGCGMDPFAEGSSAELVGLNSTNAELRGFIDQNLSPTKGNVSFVAFPVSSTNSPTKILPKTLGPINVNVGPQMIISTPQRLTSSGSVLIGSPYTPAPAMVTQTHIAEAAGWVPGDRKRAREFIDSDFSESKRSKKGDKNGKGLRHFSMKVCEKVQRKGTTSYNEVADELVSEFTNSNNHLAADSQAYDQKNIRRRVYDALNVLMAMNIISKEKKEIKWIGLPTNSAQECQNLEIEKQRRIERIKQKRAQLQELLLQQIAFKNLVQRNRQNEQQNQGPPALNSTIQLPFIIINTSRKTVIDCSISSDKFEYLFNFDNTFEIHDDIEVLKRMGMSFGLESGKCSLEDLKLAKSLVPKALEGYITDISTGPSWLNQGLLLNSTQSVSNLDLTTGATLSQSSVNQGLCLDAEVALATGQLLAPNSHQSSSAASHCSESRGETPCSFNDEDEEEDEEDSSSPE", "length": 458, "header": "tr|F6RUC4-1|F6RUC4_BOVIN Isoform 1 of Transcription factor Dp-2 OS=Bos taurus OX=9913 GN=TFDP2 PE=3 SV=1 CANONICAL=F6RUC4-1" }, "isoforms": [ { "isoform_ac": "A0A3Q1MRQ6-1", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1MRQ6/entry", "sequence": { "sequence": "MMFSCSVVSDSLRLHGNVSFVAFPVSSTNSPTKILPKTLGPINVNVGPQMIISTPQRLTSSGSVLIGSPYTPAPAMVTQTHIAEAAGWVPGDRKRAREFIDSDFSESKRSKKGDKNGKGLRHFSMKVCEKVQRKGTTSYNEVADELVSEFTNSNNHLAADSAYDQKNIRRRVYDALNVLMAMNIISKEKKEIKWIGLPTNSAQECQNLEIEKQRRIERIKQKRAQLQELLLQQIAFKNLVQRNRQNEQQNQGPPALNSTIQLPFIIINTSRKTVIDCSISSDKFEYLFNFDNTFEIHDDIEVLKRMGMSFGLESGKCSLEDLKLAKSLVPKALEGYITDISTGPSWLNQGLLLNSTQSVSNLDLTTGATLSQSSVNQGLCLDAEVALATGQLLAPNSHQSSSAASHCSESRGETPCSFNDEDEEEDEEDSSSPE", "length": 434, "header": "tr|A0A3Q1MRQ6-1|A0A3Q1MRQ6_BOVIN Computationally mapped isoform of Transcription factor OS=Bos taurus OX=9913 GN=TFDP2 PE=3 SV=2 CANONICAL=F6RUC4-1" }, "locus": { "chromosome": "1", "start_pos": 127026594, "end_pos": 126941170, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000086058.3", "url": "https://www.ensembl.org/id/ENSBTAT00000086058.3" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000074520.2", "url": "https://www.ensembl.org/id/ENSBTAP00000074520.2" } ] } }, { "isoform_ac": "A0AAA9RY78-1", "url": "https://www.uniprot.org/uniprotkb/A0AAA9RY78/entry", "sequence": { "sequence": "MQFDMTAKNVGLNSTNAELRGFIDQNLSPTKGNVSFVAFPVSSTNSPTKILPKTLGPINVNVGPQMIISTPQRLTSSGSVLIGSPYTPAPAMVTQTHIAEAAGWVPGKRSKKGDKNGKGLRHFSMKVCEKVQRKGTTSYNEVADELVSEFTNSNNHLAADSQAYDQKNIRRRVYDALNVLMAMNIISKEKKEIKWIGLPTNSAQECQNLEIEKQRRIERIKQKRAQLQELLLQQIAFKNLVQRNRQNEQQNQGPPALNSTIQLPFIIINTSRKTVIDCSISSDKFEYLFNFDNTFEIHDDIEVLKRMGMSFGLESGKCSLEDLKLAKSLVPKALEGYITDISTGPSWLNQGLLLNSTQSVSNLDLTTGATLSQSSVNQGLCLDAEVALATGQLLAPNSHQSSSAASHCSESRGETPCSFNDEDEEEDEEDSSSPE", "length": 435, "header": "tr|A0AAA9RY78-1|F6RUC4_BOVIN Computationally mapped isoform of Transcription factor Dp-2 OS=Bos taurus OX=9913 GN=TFDP2 PE=3 SV=1 CANONICAL=F6RUC4-1" }, "locus": { "chromosome": "1", "start_pos": 127026594, "end_pos": 126884793, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000102996.2", "url": "https://www.ensembl.org/id/ENSBTAT00000102996.2" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000074771.1", "url": "https://www.ensembl.org/id/ENSBTAP00000074771.1" } ] } }, { "isoform_ac": "A0AAA9S749-1", "url": "https://www.uniprot.org/uniprotkb/A0AAA9S749/entry", "sequence": { "sequence": "MQFDMTAKNVGLNSTNAELRGFIDQNLSPTKGNVSFVAFPVSSTNSPTKILPKTLGPINVNVGPQMIISTPQRLTSSGSVLIGSPYTPAPAMVTQTHIAEAAGWVPGDRKRAREFIDSDFSESKRSKKGDKNGKGLRHFSMKVCEKVQRKGTTSYNEVADELVSEFTNSNNHLAADSQAYDQKNIRRRVYDALNVLMAMNIISKEKKEIKWIGLPTNSAQECQNLEIEKQRRIERIKQKRAQLQELLLQQIAFKNLVQRNRQNEQQNQGPPALNSTIQLPFIIINTSRKTVIDCSISSDKFEYLFNFDNTFEIHDDIEVLKRMGMSFGLESGKCSLEDLKLAKSLVPKALEGYITDISTGPSWLNQGLLLNSTQSVSNLDLTTGATLSQSSVNQGLCLDAEVALATGQLLAPNSHQSSSAASHCSESRGETPCSFNDEDEEEDEEDSSSPE", "length": 451, "header": "tr|A0AAA9S749-1|F6RUC4_BOVIN Computationally mapped isoform of Transcription factor Dp-2 OS=Bos taurus OX=9913 GN=TFDP2 PE=3 SV=1 CANONICAL=F6RUC4-1" }, "locus": { "chromosome": "1", "start_pos": 127026594, "end_pos": 126884793, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000117205.2", "url": "https://www.ensembl.org/id/ENSBTAT00000117205.2" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000077991.1", "url": "https://www.ensembl.org/id/ENSBTAP00000077991.1" } ] } }, { "isoform_ac": "A0AAA9TBJ5-1", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TBJ5/entry", "sequence": { "sequence": "MSIPPVTSLVLWCNVSFVAFPVSSTNSPTKILPKTLGPINVNVGPQMIISTPQRLTSSGSVLIGSPYTPAPAMVTQTHIAEAAGWVPGDRKRAREFIDSDFSESKRSKKGDKNGKGLRHFSMKVCEKVQRKGTTSYNEVADELVSEFTNSNNHLAADSAYDQKNIRRRVYDALNVLMAMNIISKEKKEIKWIGLPTNSAQECQNLEIEKQRRIERIKQKRAQLQELLLQQIAFKNLVQRNRQNEQQNQGPPALNSTIQLPFIIINTSRKTVIDCSISSDKFEYLFNFDNTFEIHDDIEVLKRMGMSFGLESGKCSLEDLKLAKSLVPKALEGYITDISTGPSWLNQGLLLNSTQSVSNLDLTTGATLSQSSVNQGLCLDAEVALATGQLLAPNSHQSSSAASHCSESRGETPCSFNDEDEEEDEEDSSSPE", "length": 431, "header": "tr|A0AAA9TBJ5-1|F6RUC4_BOVIN Computationally mapped isoform of Transcription factor Dp-2 OS=Bos taurus OX=9913 GN=TFDP2 PE=3 SV=2 CANONICAL=F6RUC4-1" }, "locus": { "chromosome": "1", "start_pos": 127026594, "end_pos": 126957584, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000126363.2", "url": "https://www.ensembl.org/id/ENSBTAT00000126363.2" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000094211.2", "url": "https://www.ensembl.org/id/ENSBTAP00000094211.2" } ] } }, { "isoform_ac": "A0ABI0P4B0-1", "url": "https://www.uniprot.org/uniprotkb/A0ABI0P4B0/entry", "sequence": { "sequence": "MYNSKYAEFMSNVSFVAFPVSSTNSPTKILPKTLGPINVNVGPQMIISTPQRLTSSGSVLIGSPYTPAPAMVTQTHIAEAAGWVPGDRKRAREFIDSDFSESKRSKKGDKNGKGLRHFSMKVCEKVQRKGTTSYNEVADELVSEFTNSNNHLAADSAYDQKNIRRRVYDALNVLMAMNIISKEKKEIKWIGLPTNSAQECQNLEIEKQRRIERIKQKRAQLQELLLQQIAFKNLVQRNRQNEQQNQGPPALNSTIQLPFIIINTSRKTVIDCSISSDKFEYLFNFDNTFEIHDDIEVLKRMGMSFGLESGKCSLEDLKLAKSLVPKALEGYITDISTGPSWLNQGLLLNSTQSVSNLDLTTGATLSQSSVNQGLCLDAEVALATGQLLAPNSHQSSSAASHCSESRGETPCSFNDEDEEEDEEDSSSPE", "length": 429, "header": "tr|A0ABI0P4B0-1|A0ABI0P4B0_BOVIN Computationally mapped isoform of Transcription factor OS=Bos taurus OX=9913 GN=TFDP2 PE=3 SV=1 CANONICAL=F6RUC4-1" }, "locus": { "chromosome": "1", "start_pos": 127026594, "end_pos": 126956309, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000143809.1", "url": "https://www.ensembl.org/id/ENSBTAT00000143809.1" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000106241.1", "url": "https://www.ensembl.org/id/ENSBTAP00000106241.1" } ] } }, { "isoform_ac": "A0ABI0P516-1", "url": "https://www.uniprot.org/uniprotkb/A0ABI0P516/entry", "sequence": { "sequence": "MLDPKCDRKRAREFIDSDFSESKRSKKGDKNGKGLRHFSMKVCEKVQRKGTTSYNEVADELVSEFTNSNNHLAADSAYDQKNIRRRVYDALNVLMAMNIISKEKKEIKWIGLPTNSAQECQNLEIEKQRRIERIKQKRAQLQELLLQQIAFKNLVQRNRQNEQQNQGPPALNSTIQLPFIIINTSRKTVIDCSISSDKFEYLFNFDNTFEIHDDIEVLKRMGMSFGLESGKCSLEDLKLAKSLVPKALEGYITDISTGPSWLNQGLLLNSTQSVSNLDLTTGATLSQSSVNQGLCLDAEVALATGQLLAPNSHQSSSAASHCSESRGETPCSFNDEDEEEDEEDSSSPE", "length": 349, "header": "tr|A0ABI0P516-1|A0ABI0P516_BOVIN Computationally mapped isoform of Transcription factor OS=Bos taurus OX=9913 GN=TFDP2 PE=3 SV=1 CANONICAL=F6RUC4-1" }, "locus": { "chromosome": "1", "start_pos": 127026594, "end_pos": 126977585, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000143481.1", "url": "https://www.ensembl.org/id/ENSBTAT00000143481.1" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000106744.1", "url": "https://www.ensembl.org/id/ENSBTAP00000106744.1" } ] } }, { "isoform_ac": "F6RUC4-1", "url": "https://www.uniprot.org/uniprotkb/F6RUC4/entry", "sequence": { "sequence": "MGCGMDPFAEGSSAELVGLNSTNAELRGFIDQNLSPTKGNVSFVAFPVSSTNSPTKILPKTLGPINVNVGPQMIISTPQRLTSSGSVLIGSPYTPAPAMVTQTHIAEAAGWVPGDRKRAREFIDSDFSESKRSKKGDKNGKGLRHFSMKVCEKVQRKGTTSYNEVADELVSEFTNSNNHLAADSQAYDQKNIRRRVYDALNVLMAMNIISKEKKEIKWIGLPTNSAQECQNLEIEKQRRIERIKQKRAQLQELLLQQIAFKNLVQRNRQNEQQNQGPPALNSTIQLPFIIINTSRKTVIDCSISSDKFEYLFNFDNTFEIHDDIEVLKRMGMSFGLESGKCSLEDLKLAKSLVPKALEGYITDISTGPSWLNQGLLLNSTQSVSNLDLTTGATLSQSSVNQGLCLDAEVALATGQLLAPNSHQSSSAASHCSESRGETPCSFNDEDEEEDEEDSSSPE", "length": 458, "header": "tr|F6RUC4-1|F6RUC4_BOVIN Isoform 1 of Transcription factor Dp-2 OS=Bos taurus OX=9913 GN=TFDP2 PE=3 SV=1 CANONICAL=F6RUC4-1" }, "locus": { "chromosome": "1", "start_pos": 127026594, "end_pos": 126891384, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000008169.6", "url": "https://www.ensembl.org/id/ENSBTAT00000008169.6" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000008169.5", "url": "https://www.ensembl.org/id/ENSBTAP00000008169.5" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [], "orthologs": [], "go_annotation": { "categories": [ { "name": "Molecular Function", "total": 4, "go_terms": [ { "name": "DNA binding", "id": "GO:0003677", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003677", "evidence": [ { "database": "UniProtKB", "id": "F6RUC4", "url": "https://www.uniprot.org/uniprotkb/F6RUC4" } ], "pmid": "" }, { "name": "protein domain specific binding", "id": "GO:0019904", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0019904", "evidence": [ { "database": "UniProtKB", "id": "F6RUC4", "url": "https://www.uniprot.org/uniprotkb/F6RUC4" } ], "pmid": "" }, { "name": "RNA polymerase II transcription regulatory region sequence-specific DNA binding", "id": "GO:0000977", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000977", "evidence": [ { "database": "UniProtKB", "id": "F6RUC4", "url": "https://www.uniprot.org/uniprotkb/F6RUC4" } ], "pmid": "" }, { "name": "DNA-binding transcription activator activity, RNA polymerase II-specific", "id": "GO:0001228", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0001228", "evidence": [ { "database": "UniProtKB", "id": "F6RUC4", "url": "https://www.uniprot.org/uniprotkb/F6RUC4" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 4, "go_terms": [ { "name": "nucleus", "id": "GO:0005634", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005634", "evidence": [ { "database": "UniProtKB", "id": "F6RUC4", "url": "https://www.uniprot.org/uniprotkb/F6RUC4" } ], "pmid": "" }, { "name": "transcription regulator complex", "id": "GO:0005667", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005667", "evidence": [ { "database": "UniProtKB", "id": "F6RUC4", "url": "https://www.uniprot.org/uniprotkb/F6RUC4" } ], "pmid": "" }, { "name": "nucleoplasm", "id": "GO:0005654", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005654", "evidence": [ { "database": "UniProtKB", "id": "F6RUC4", "url": "https://www.uniprot.org/uniprotkb/F6RUC4" } ], "pmid": "" }, { "name": "RNA polymerase II transcription regulator complex", "id": "GO:0090575", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0090575", "evidence": [ { "database": "UniProtKB", "id": "F6RUC4", "url": "https://www.uniprot.org/uniprotkb/F6RUC4" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 4, "go_terms": [ { "name": "DNA-templated transcription", "id": "GO:0006351", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006351", "evidence": [ { "database": "UniProtKB", "id": "F6RUC4", "url": "https://www.uniprot.org/uniprotkb/F6RUC4" } ], "pmid": "" }, { "name": "regulation of DNA-templated transcription", "id": "GO:0006355", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006355", "evidence": [ { "database": "UniProtKB", "id": "F6RUC4", "url": "https://www.uniprot.org/uniprotkb/F6RUC4" } ], "pmid": "" }, { "name": "regulation of cell cycle", "id": "GO:0051726", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0051726", "evidence": [ { "database": "UniProtKB", "id": "F6RUC4", "url": "https://www.uniprot.org/uniprotkb/F6RUC4" } ], "pmid": "" }, { "name": "negative regulation of DNA-templated transcription", "id": "GO:0045892", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0045892", "evidence": [ { "database": "UniProtKB", "id": "F6RUC4", "url": "https://www.uniprot.org/uniprotkb/F6RUC4" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 20, "end_pos": 22, "annotation": "n_glycosylation_sequon" }, { "start_pos": 281, "end_pos": 283, "annotation": "n_glycosylation_sequon" }, { "start_pos": 292, "end_pos": 294, "annotation": "n_glycosylation_sequon" }, { "start_pos": 33, "end_pos": 35, "annotation": "n_glycosylation_sequon" }, { "start_pos": 378, "end_pos": 380, "annotation": "n_glycosylation_sequon" }, { "start_pos": 40, "end_pos": 42, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "F6RUC4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F6RUC4" }, { "id": "SM01372", "database": "SMART", "url": "http://smart.embl.de/smart/do_annotation.pl?DOMAIN=SM01372" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "E2F/DP family winged-helix DNA-binding", "eco_id": "ECO_0000259", "start_pos": 138, "end_pos": 220, "start_aa": "Lys", "end_aa": "Gly", 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"common_name": "Bovine", "glygen_name": "Bovine", "reference_species": "Bos taurus [9913]" } ], "gene": [ { "name": "SH3TC1", "url": "https://www.uniprot.org/uniprotkb/G3MZW4", "locus": { "chromosome": "6", "start_pos": 114552980, "end_pos": 114489894, "strand": "-", "evidence": [ { "database": "Ensembl Gene", "id": "ENSBTAG00000047876", "url": "https://www.ensembl.org/id/ENSBTAG00000047876" } ] } } ], "crossref": [ { "id": "ENSBTAG00000047876", "url": "https://bgee.org/?page=gene&gene_id=ENSBTAG00000047876", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "cd11885", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd11885", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "100300032", "url": "https://www.ncbi.nlm.nih.gov/gene/100300032", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR001452", "url": "https://www.ebi.ac.uk/interpro/entry/IPR001452", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR011990", "url": "https://www.ebi.ac.uk/interpro/entry/IPR011990", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR019734", "url": "https://www.ebi.ac.uk/interpro/entry/IPR019734", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR036028", "url": "https://www.ebi.ac.uk/interpro/entry/IPR036028", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR042772", "url": "https://www.ebi.ac.uk/interpro/entry/IPR042772", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "FTNEQQG", "url": "https://omabrowser.org/oma/group/FTNEQQG/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "PTHR22647", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR22647", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR22647:SF3", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR22647:SF3", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "A0A3Q1LSD4", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1LSD4", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A3Q1LSD4-1", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1LSD4-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A3Q1LXW5", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1LXW5", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A3Q1LXW5-1", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1LXW5-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "G3MZW4", "url": "https://www.uniprot.org/uniprotkb/G3MZW4", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "G3MZW4-1", "url": "https://www.uniprot.org/uniprotkb/G3MZW4-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MCAFLPGQASRGRDHREGPEQEQRQRSAWHAEPLAVRPPSAMEGPEEPAPRGNGPAGPWGGSGDHGVREVAKSTSVSWERPRPEEAKATVRGDLTLQLLAVRRKSGLPDPNLQQALRGQLRLLENESCEVARTLGELSARLLSIHSDQDRLVVTFKTFEEIWKFSTYHALGFTHHCLENLLMDQAFWLLEPDEDQETAVRVQVDAEALRLAYESLLVQEGPFFVLCPDHHVRVRNGPQPFRRPPRGPQADAATAVDSPAPSPGTSSEAEGAAAAAPEPLIPFHQWALRVPKDSVNDPLGGPVAPDVQLMAMGPALAVADCQGSGPEEMTFRSGDRIEILGAQVPGLPWCLGRHTASGQVGFVRTSLINVQGQASDLENVIFLSEEERSFFSREGHFSEEEARQLLRRTSSTNVCTMYRLDTSEEAETQQQQEEQEMSPPCLNPEPQEILQTVKNVLKQCKSCRGCPEEPGSPGVHRASSGASLPDTEEPFFCLDTGDDWADPEALGSQLLFLDSPGFQAGFQGLYDLSPPTLSSVFGGFTDEEELVRRLAEARGVAKKAGLPMALARLCFLLGRLCVRQLKLSQARVYFEEALGVLGGRFGDLVLVAAVYTSLASVHLRQKNKEKCAQVVPKALALLLGTPGHVGSSEADSSLLTLALRRAISSRSPQAEARACFLLAKHHARLKQPEEAMPFLERLLLLLPEAAGTPGTSWPMDCYLLLASIYSQRCLPHLALSCIRVASLRAQGSLGSALRSAALVLQNSPRLPLLPAQLAHYLRRALATLASGSGQALHGPVYASLAQLYSQHGWQGRAIAFMAQAVETDARLGGCTVVDRLVALAWLHVLHRQSPAALGILESLLEAAVATPDQEGLITNMMAIALKRTGRTRRAAESYYRALRVARRLSRPQNEAVVLANFGALCLQAGAGGLAQHYLLEAVKLFSRLPSREGSPDFTRVLLRLGDLCTRRALARQAKCYYEWAFLVAVEMDHWESQLLAVQRLCHFYSAVVPNEARCVVYHEFQLSLARRVNDKVLEGQLLETISQLYLSLGTERAYRSALEYTKRSLGVFIDLLKKDKEAHAWLQAGKIYYVLRQSELVDLYIQAAQNAALYTGDPGLGLQLFEEAGDIFFNGTWDREKAVSFYRDRALPLAVSTGSREAELRLCNKLSALLAETEAPQEGLEFAHTALALSLTLGDQLNQRVACHRLAALHHRLGHGELAEHFYLKALSLCTSPLEFDEETLYYVKVYLALGNIIFYDLKDPLDAAGYYQLALAAAMGLGSKRAQMKLCARLASIYHHSLLDRETSLFFYQKARTFATELSVRRGRLAPGPPS", "length": 1331, "header": "tr|G3MZW4-1|G3MZW4_BOVIN Isoform 1 of SH3 domain and tetratricopeptide repeats 1 OS=Bos taurus OX=9913 GN=SH3TC1 PE=4 SV=3 CANONICAL=G3MZW4-1" }, "isoforms": [ { "isoform_ac": "A0A3Q1LSD4-1", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1LSD4/entry", "sequence": { "sequence": "MEGPEEPAPRGNGPAGPWGGSGDHGVREVAKSTSVSWERPRPEEAKATVRGDLTLQLLAVRRKSGLPDPNLQQALRGQLRLLENESCEVARTLGELSARLLSIHSDQDRLVVTFKTFEEIWKFSTYHALGFTHHCLENLLMDQAFWLLEPDEDQETAVRVQVDAEALRLAYESLLVQEGPFFVLCPDHHVRVRNGPQPFRRPPRGPQADAATAVDSPAPSPGTSSEAEGAAAAAPEPLIPFHQWALRVPKDSVNDPLGGPVAPDVQLMAMGPALAVADCQGSGPEEMTFRSGDRIEILGAQVPGLPWCLGRHTASGQVGFVRTSLINVQGQASDLENVIFLSEEERSFFSREGHFSEEEARQLLRRTSSTNVCTMYRLDTSEEAETQQQQEEQEMSPPCLNPEPQEILQTVKNVLKQCKSCRGCPEEPGSPGVHRASSGASLPDTEEPFFCLDTGDDWADPEALGSQLLFLDSPGFQAGFQGLYDLSPPTLSSVFGGFTDEEELVRRLAEARGVAKKAGLPMALARLCFLLGRLCVRQLKLSQARVYFEEALGVLGGRFGDLVLVAAVYTSLASVHLRQKNKEKCAQVVPKALALLLGTPGHVGSSEADSSLLTLALRRAISSRSPQAEARACFLLAKHHARLKQPEEAMPFLERLLLLLPEAAGTPGTSWPMDCYLLLASIYSQRCLPHLALSCIRVASLRAQGSLGSALRSAALVLQNSPRLPLLPAQLAHYLRRALATLASGSGQALHGPVYASLAQLYSQHGWQGRAIAFMAQAVETDARLGGCTVVDRLVALAWLHVLHRQSPAALGILESLLEAAVATPDQEGLITNMMAIALKRTGRTRRAAESYYRALRVARRLSRPQNEAVVLANFGALCLQAGAGGLAQHYLLEAVKLFSRLPSREGSPDFTRVLLRLGDLCTRRALARQAKCYYEWAFLVAVEMDHWESQLLAVQRLCHFYSAVVPNEARCVVYHEFQLSLARRVNDKVLEGQLLETISQLYLSLGTERAYRSALEYTKRSLGVFIDLLKKDKEAHAWLQAGKIYYVLRQSELVDLYIQAAQNAALYTGDPGLGLQLFEEAGDIFFNGTWDREKAVSFYRDRALPLAVSTGSREAELRLCNKLSALLAETEAPQEGLEFAHTALALSLTLGDQLNQRVACHRLAALHHRLGHGELAEHFYLKALSLCTSPLEFDEETLYYVKVYLALGNIIFYDLKGIFPIQGSSPGLRVAGGFFTS", "length": 1238, "header": "tr|A0A3Q1LSD4-1|G3MZW4_BOVIN Computationally mapped isoform of SH3 domain and tetratricopeptide repeats 1 OS=Bos taurus OX=9913 GN=SH3TC1 PE=4 SV=1 CANONICAL=G3MZW4-1" }, "locus": { "chromosome": "6", "start_pos": 114549240, "end_pos": 114519002, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000073068.2", "url": "https://www.ensembl.org/id/ENSBTAT00000073068.2" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000060144.2", "url": "https://www.ensembl.org/id/ENSBTAP00000060144.2" } ] } }, { "isoform_ac": "A0A3Q1LXW5-1", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1LXW5/entry", "sequence": { "sequence": "MEGPEEPAPRGNGPAGPWGGSGDHGVREVAKSTSVSWERPRPEEAKATVRGDLTLQLLAVRRKSGLPDPNLQQALRGQLRLLENESCEVARTLGELSARLLSIHSDQDRLVVTFKTFEEIWKFSTYHALGFTHHCLENLLMDQAFWLLEPDEDQETAVRVQVDAEALRLAYESLLVQEGPFFVLCPDHHVRVRNGPQPFRRPPRGPQADAATAVDSPAPSPGTSSEAEGAAAAAPEPLIPFHQWALRVPKDSVNDPLGGPVAPDVQLMAMGPALAVADCQGSGPEEMTFRSGDRIEILGAQVPGLPWCLGRHTASGQVGFVRTSLINVQGQASDLENVIFLSEEERSFFSREGHFSEEEARQLLRRTSSTNVCTMYRLDTSEEAETQQQQEEQEMSPPCLNPEPQEILQTVKNVLKQCKSCRGCPEEPGSPGVHRASSGASLPDTEEPFFCLDTGDDWADPEALGSQLLFLDSPGFQAGFQGLYDLSPPTLSSVFGGFTDEEELVRRLAEARGVAKKAGLPMALARLCFLLGRLCVRQLKLSQARVYFEEALGVLGGRFGDLVLVAAVYTSLASVHLRQKNKEKCAQVVPKALALLLGTPGHVGSSEADSSLLTLALRRAISSRSPQAEARACFLLAKHHARLKQPEEAMPFLERLLLLLPEAAGTPGTSWPMDCYLLLASIYSQRCLPHLALSCIRVASLRAQGSLGSALRSAALVLQNSPRLPLLPAQLAHYLRRALATLASGSGQALHGPVYASLAQLYSQHGWQGRAIAFMAQAVETDARLGGCTVVDRLVALAWLHVLHRQSPAALGILESLLEAAVATPDQEGLITNMMAIALKRTGRTRRAAESYYRALRVARRLSRPQNEAVVLANFGALCLQAGAGGLAQHYLLEAVKLFSRLPSREGSPDFTRVLLRLGDLCTRRALARQAKCYYEWAFLVAVEMDHWESQLLAVQRLCHFYSAVVPNEARCVVYHEFQLSLARRVNDKVLEGQLLETISQLYLSLGTERAYRSALEYTKRSLGVFIDLLKKDKEAHAWLQAGKIYYVLRQSELVDLYIQAAQNAALYTGDPGLGLQLFEEAGDIFFNGTWDREKAVSFYRDRALPLAVSTGSREAELRLCNKLSALLAETEAPQEGLEFAHTALALSLTLGDQLNQRVACHRLAALHHRLGHGELAEHFYLKALSLCTSPLEFDEETLYYVKVYLALGNIIFYDLKDPLDAAGYYQLALAAAMGLGSKRAQMKLCARLASIYHHSLLDRETSLFFYQKARTFATELSVRRGRLAPGPPS", "length": 1290, "header": "tr|A0A3Q1LXW5-1|G3MZW4_BOVIN Computationally mapped isoform of SH3 domain and tetratricopeptide repeats 1 OS=Bos taurus OX=9913 GN=SH3TC1 PE=4 SV=1 CANONICAL=G3MZW4-1" }, "locus": { "chromosome": "6", "start_pos": 114551976, "end_pos": 114519002, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000078509.2", "url": "https://www.ensembl.org/id/ENSBTAT00000078509.2" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000062337.1", "url": "https://www.ensembl.org/id/ENSBTAP00000062337.1" } ] } }, { "isoform_ac": "G3MZW4-1", "url": "https://www.uniprot.org/uniprotkb/G3MZW4/entry", "sequence": { "sequence": "MCAFLPGQASRGRDHREGPEQEQRQRSAWHAEPLAVRPPSAMEGPEEPAPRGNGPAGPWGGSGDHGVREVAKSTSVSWERPRPEEAKATVRGDLTLQLLAVRRKSGLPDPNLQQALRGQLRLLENESCEVARTLGELSARLLSIHSDQDRLVVTFKTFEEIWKFSTYHALGFTHHCLENLLMDQAFWLLEPDEDQETAVRVQVDAEALRLAYESLLVQEGPFFVLCPDHHVRVRNGPQPFRRPPRGPQADAATAVDSPAPSPGTSSEAEGAAAAAPEPLIPFHQWALRVPKDSVNDPLGGPVAPDVQLMAMGPALAVADCQGSGPEEMTFRSGDRIEILGAQVPGLPWCLGRHTASGQVGFVRTSLINVQGQASDLENVIFLSEEERSFFSREGHFSEEEARQLLRRTSSTNVCTMYRLDTSEEAETQQQQEEQEMSPPCLNPEPQEILQTVKNVLKQCKSCRGCPEEPGSPGVHRASSGASLPDTEEPFFCLDTGDDWADPEALGSQLLFLDSPGFQAGFQGLYDLSPPTLSSVFGGFTDEEELVRRLAEARGVAKKAGLPMALARLCFLLGRLCVRQLKLSQARVYFEEALGVLGGRFGDLVLVAAVYTSLASVHLRQKNKEKCAQVVPKALALLLGTPGHVGSSEADSSLLTLALRRAISSRSPQAEARACFLLAKHHARLKQPEEAMPFLERLLLLLPEAAGTPGTSWPMDCYLLLASIYSQRCLPHLALSCIRVASLRAQGSLGSALRSAALVLQNSPRLPLLPAQLAHYLRRALATLASGSGQALHGPVYASLAQLYSQHGWQGRAIAFMAQAVETDARLGGCTVVDRLVALAWLHVLHRQSPAALGILESLLEAAVATPDQEGLITNMMAIALKRTGRTRRAAESYYRALRVARRLSRPQNEAVVLANFGALCLQAGAGGLAQHYLLEAVKLFSRLPSREGSPDFTRVLLRLGDLCTRRALARQAKCYYEWAFLVAVEMDHWESQLLAVQRLCHFYSAVVPNEARCVVYHEFQLSLARRVNDKVLEGQLLETISQLYLSLGTERAYRSALEYTKRSLGVFIDLLKKDKEAHAWLQAGKIYYVLRQSELVDLYIQAAQNAALYTGDPGLGLQLFEEAGDIFFNGTWDREKAVSFYRDRALPLAVSTGSREAELRLCNKLSALLAETEAPQEGLEFAHTALALSLTLGDQLNQRVACHRLAALHHRLGHGELAEHFYLKALSLCTSPLEFDEETLYYVKVYLALGNIIFYDLKDPLDAAGYYQLALAAAMGLGSKRAQMKLCARLASIYHHSLLDRETSLFFYQKARTFATELSVRRGRLAPGPPS", "length": 1331, "header": "tr|G3MZW4-1|G3MZW4_BOVIN Isoform 1 of SH3 domain and tetratricopeptide repeats 1 OS=Bos taurus OX=9913 GN=SH3TC1 PE=4 SV=3 CANONICAL=G3MZW4-1" }, "locus": { "chromosome": "6", "start_pos": 114551976, "end_pos": 114489911, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000066026.3", "url": "https://www.ensembl.org/id/ENSBTAT00000066026.3" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000055118.3", "url": "https://www.ensembl.org/id/ENSBTAP00000055118.3" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [], "orthologs": [ { "uniprot_canonical_ac": "A0A8C2MJK4-1", "protein_name": "SH3 domain and tetratricopeptide repeat-containing protein 1", "gene_name": "Sh3tc1", "tax_id": 10029, "organism": "Cricetulus griseus", "sequence": { "sequence": "MRSSREEEATSEELSTMGQDLEEPPGGCSHGDQIHSVSVSLPIGQERAGPEEAVRSDVASPPSMAELAAETPSGRKAVFPTDLTLQLLAVRRKSGLRSPSLQQALRSRLRLLENDSREVARVLGELSARLLSIHSDQDRIVVTFKTFEEIWKFSTYHALGFTHHCLENLLVDQTFWLLSPSEEEETAILMYVSKEALKQTHKKLLTQEGPFFVRCPEHRVRMMMGPQGAGKGPQALRRASGVPLGVAILETNSSSPMPSTSSNVEAAEADPEPLTPFHQWTLRVPWDPIDESMDGPGTPDAQLMGLGLASAVGDFQGSGPEEMSFCVGDVIEIIGAQVPGLPWCVGRHVASGQVGFVRTGLVSMQGPASDLESAIFLSEEERSFFRSEGHFSDEDARRLLSRTSCTDVCTTCSLDWLEEAEGEQLEQQELSLPHLNPEPHETLHMVKDILERCKACPDHPEDPVSWSLGEVSNRVSSPDLEEPPFCLDPEVDWTDPEPLDSLLQVLNAPGYEAHFRGLYDISLPWLSTALCGFDDEEELAGCLAQARGVAKKVNLGMALARLCLLLGRLCARKLKLSQARVYFEEALGALEGSFGDLSLVAAVYTSLATVYLKQKNGEKCVQVAPKAAALLLGTPGHAYSTDTELLKYALRRAICGLSPQAEARACFLLARHYTHLKQPEEALPYLERLLRLNRDVGTPQASWPKDCYLLLADIYGRKCLPHLALSCLRVSSLWTRCSLASSLRSVDLVLRNAPGPNSQRRANHRLPTQIAYYLRKALASLTPGTGQALCGPLYASLAQLYSHHQQHNQAIAFMSQAAEADTAAGIYPVVDRLVALAWLHMLCGKNLVAMDILKSILDAAVANKDQECVMTNMVAMALKRTGRTRQAAEGYFRALHMAYSQGHLKSQAVVLANFGALCLQAGARSLAQHYLREAVGLFSQLPSSVCGRDFTQVLLWLGQLCTRRALHQQAKCYYEWAFLVAVEMDHLESQLQAVQKLCHFYSKVMPNEVRCVIYHEFQLALARRTADKVLEGQLLEAISQLYLSLGTERAYKSALDYTKRSLGIFIDLQQKEKEARAWLQAGKIYYILRQNELVDLYIQVAQNAALYTGDPKLGLELFEAAGDIFFNGTWEREKAVSFYRDRALPLAVTIGNQEAELRLCNKLVALLSALEAPQEGLEFAHEALALSITLGDRLNERVAYHRLATLHHQLGHGELAEHFFLKALSLCNSPLEFDEETLYYVKVYLVLGDIIFYDLKDPFDAAGYYQLALAAAVDLGHKKAQLKIYTRLATIYHHFLMDREMSLFFYQKARTFASELNLRRTNLVPQRFCGRTPWLAPGYPS", "length": 1341 }, "evidence": [ { "id": "G3MZW4", "url": "https://omabrowser.org/oma/group/G3MZW4/", "database": "OMA" } ], "glygen_name": "Hamster", "common_name": "Chinese hamster" }, { "uniprot_canonical_ac": "D3ZLQ9-1", "protein_name": "SH3 domain and tetratricopeptide repeats 1", "gene_name": "Sh3tc1", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MRSFREEEATSEDLSTMGQGPEEPPGGCSLEDKIQSISMGLPTSQERTGPEEAEATTVRGDVAPPCGMVGQAAEPPSNQMAVYPTDLTLQLLAVRRKSGLRSPSLQQTLRSRLRLLENDSREVARVLGELSARLLSIHSDQDRIVVTFKTFEEIWKFSTYHALGFTHHCLENLLVDQTFWLLSPSEEEETAILIYVNKDALKQTHKSLLAQEGSFFVLCPDHCVRRTKEPQGAGKGPQTLRRASGVTLGVPVVETVSSSPTPSMSSKAEAVEAEPEPLTPFHQWTLRVPWDPIDESMSGPGTPDAQFMRFGLASAIADFQGSGPEEMSFSVGDVIEIVGAQVPGLPWCLGQHMASGQVGFVRTGLVRMQGPASDLESSIFLSEEERSFFRSEAHFSDEDARRLLCRTSGTDVCTTCSLDWLEEAEGEQLEQQEMSLPHLNPEPHESLHMVKNVLEKCKACPDHPEDPVSWSLGAVSSRVSSPDLEEPPFCLDPDDDWTDPEPPDSLLQVLSAPGYRAQFRSLYDISLPCLSTALYSFDDEEELAERLAQARGVAKKVDLGMALARLCLLLGRLCARKLKLSQARVYFEEALGALEGSFGDLSLVAAVYSSLATVYLKQKNGEKCVQLAPKAAALLLGTPGHSCSTDAELLKYALRRVVCGLSPQAEARACFLLARHYTHLKQPEEALPYLERLLRLNRDVGTPQASWPEDCYLLLADIYGRKCLPHLALSCLKVSSLWTRCSLAGSLRSVDLVLQNAPGPNSQRSTGHSLPSQIAHYLRQALASLPPGTGQTLRGPLYASLAQLYSYHQQYGQAIAFMSQAAEADTAAGVHPVVDRLVALAWLHLLCGKSLVAMDILKCVSDAAVANKDQECVMMNMVAMALKRMGRTRQAAEGYFRALHMAYSQGHLQSQAVVLANFGALCLQAGARSLAQHYLREAVGLFSQLPSGVCGRDFTQVLLWLGQLCTRRTLPQQAKCYYEWAFLVAVETDHLESQLQAVQKLCHFYSKVMPNEVRCVIYHEFQLALARKTADKVLEGQLLEAISQLYLSLGTERAYKSALDYTKRSLGIFIDLQQKEKEARAWLQAGKIYYILRQNELVDLYIQVAQNAALYTGDPKLGLELFEAAGDIFFNGTWEREKAMKVPCTHDRALPLAVTVGDQEVELRLCNKLVALLSALEAPQEGLEFAHEALALSITLGDRLNERVAYHRLATLHHRLGHGELAEHFFLKALSLCTSPLEFDEETLYYVKVYLVLGDIIFYELKDPFDAAGYYQLALAAAVDLGHKKAQLKIYTRLATIYHNFLMDREMSLFFYQKARTFASELNLRRTNLVPQHFCSRAPWLAPGYPS", "length": 1347 }, "evidence": [ { "id": "G3MZW4", "url": "https://omabrowser.org/oma/group/G3MZW4/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "F1NC54-1", "protein_name": "SH3 domain and tetratricopeptide repeats 1", "gene_name": "SH3TC1", "tax_id": 9031, "organism": "Gallus gallus", "sequence": { "sequence": "MSSLAAGGSSVSVLSSKVTTELGIPAPSLEGKQDSNLERKETEQGRCVPGWICETAVATVSAARGGDKTDTLQEQMDYPQNEKCMNVSSRTLLSQAENFPTDISLKLTMVRRKSGRPDPRLQRQLRGQLRLLENDSREVTAVFSELSARLLSIHSDQDLIVVTFKTFEEIWKFLTYHSLGFVNHCMENLFLDQSFWLYSQEEEETGIEVCINEKSLNLMYRSLLVQEGAFFVLCPDNLVRKITATDCEINTYFEAGAFTADVAGGSVDGDMTMPSNVPLEPLIPFHQWFLKVYSDPIDVAYKTESKSIRQVATGSCLAVMNYDSAVPEEISFQEGDEIEILGYLIECMEWFVGRHLFTGHVGFVKTSHVKLDLPGNKAADLDFLKAEELSFFPQEKNVEEVVHLLKQTSITDVCSVYRIDQLEEQEFQKTRECEIPCPHSNMATTSKKNGKIEEFVEKFKKLEVTQAEGPATERKESASSSHTEIFPSPEGPCFYIYQDDGQESDVFESLLLFLNNKEYESDFKNLYDFSYTFINSMFYGFSEEDELLSFFSVARELAKKAGMSWALARLCFLLGRLSVKKVKFSQARVYFEEALGAVTGGFTDLYFVIALYTNLTVIYLTQKNKEKCSHVFDKATSLLMGIPNHICSADLESDILKHALKRTILSQNKHAEARACFLLAKHYTARKQHEEALPFLERLQLLFNDLGLQNNLSKNCYFNLAESYNEKCLPHIVLSCIKVSSSQNSSTLMDSLKRIDLVIKNAPKLYGLRKLRQILPSQIAPYLTQALSSAFTNEQQGLCSTIYLSLAKLYSHHKQYGKAIIYMMKALDSDTSAKPEETINYLVSLAWLYILYRQYDVAATILNAVVDSSGSNPQQLGVAYNMLAIALKRTNNTKKAVESCYKALRLSEEANMTHNQAISLANFGMLCLHAAAGKLAEHYYIKAVKLFAKLPSMDCGQEFIQTLLQLGRYYVNRTQREKGRFYYEWAFLVAMEISHLESQLQAIKLLCQFYSTVVPNEAQCVIYNEYQLSLARKMSNKVLEGQILETISQLYLSLGTERAYRSALEYTKRSLGIFIDLQKKEREAYAWLRAGKIYYILRQNELVDLYIQVAQDAALCTGDPNLAMELFEAAGDIFFNGKWEKEKAVPFYRDRALPLAVESGNKNTELRLCNKLVELLVNLKVYEESMEYAKASLILSVNLGNQLNERIAYHRLAAIHHHLGHCELAEHFYLKALSLCSSPLEFEEETLYYVKVYLNLGDIIFYDLKDPFDAAGYYQLALAAAMDLGNKKAQLKIYTRLAIIYHNFLVDREMSLFFYQKARTFATELNVRRINLAPDQCYKSL", "length": 1341 }, "evidence": [ { "id": "G3MZW4", "url": "https://omabrowser.org/oma/group/G3MZW4/", "database": "OMA" } ], "glygen_name": "Chicken", "common_name": "Chicken" }, { "uniprot_canonical_ac": "F1QHY2-1", "protein_name": "SH3 domain and tetratricopeptide repeat-containing protein 1 isoform X1", "gene_name": "sh3tc1", "tax_id": 7955, "organism": "Danio rerio", "sequence": { "sequence": "MSAAARRNSSKTGNGVEPDPDRVRTLRRELSNEYTRNELDNIMESSSRDYRISRGSFKGTPGASDDNVPTVLAMQLTMVEGPDRLPADENTQEVLCRKLCVLEADLSGVVTLISELSAHFVSIYSEERTIFITFKTIDDIWRFSTYYRMGFLGQCMENLLMDQEFWLTSLDHHSGIEISIKEETLNLMYKGFLMQEGSFFGCCTANQMFDSSTSGKDLYLEKGDIALFEPPFLGSGWTVLSLAEGSRGTKAKPALEPVTPFHEWFLKSCPETVLVGGGKDTIDLPFQIAVGVCETIEDYDADGPDELSFQTGERIIIQGLLVACFEWFMGQSEKTGDTGLVKTRLVKATGSFCESSDMFLKDEDRQIVTLDHEQIKEETLSLLKKTCQCDVGTNYKLDVAKEISGSVQSKSHQTEVSNLKQKVSHVLSEAQETQRNEVSALIINHQKEKQRNDTEVSQDTPRFSVCSDKEGSSPDEHHALLSFLSSREHQPEFTLLYRAYPEFLMTHFEGHSDEEDIVTYLGIARELARKKRVSWAQSRICFLLGQLCAGRSKFSQARVYYEEALNVPRDSFSDMLLLSALYSNLALIYLTQKNHEKFFALSERFSALLMAVPDCLFGCEDPEVLKYVLKKAVLAKSQLAEARACFLLAKLHLKIKDAVSVVPFIERLLILADELPEVCDEAMCHVSLVLARLYSEQGLPRLAESCARRASLQVGVTVSHCLCGVSLLLENAPELHGVSIPTQVAPFLTRAAALAPLHNDPTLVHIHALCLSWLFHRHNMPERAVRYMCAILEHSSMSSIGKSDATTAFIWLAWLYICNQQPGTALEVLDAVLASLPEHCTTHLEGVVYNMRAISYRHSADIRQAAESYQAAIEICEEFEDRHNWAVALANFGFMCLQVKAKRLAEENLCQSMELFSGLEDEGHELSFILVLLQLGRHFISQGNSESGKIYYEWALLIATYIDNIESQLHTTRHLCELYEDVCPDEAQCIIYNEHQLNLLQRIGDKSSEAEILEKISQLYLNLATEKANRAALDYTKRSLAIFIDLGKKRKEAHAWLRAGKIYHILQQTELVDLYVQVAQDMALNTGDTLFTLEMLEAAGDVFFNSSQDRDKAICFYRDRALPIAVKTSSVGSQLRLCNKLSELLLQLGQSSEALEFAQTALDISVSLADRLNERVAFHRLATLYHCLGQFEMAEHHFLKALSLCPSPLQYDEEALYYVRVYQTLGDIIFYDVKDPFDAAGYYHLALAAAMDLGNKRSQLQLCTRLATIYHNFLMDRELSLFFYQRARVFANDLHIRRINLAPDYSFRSTSQYKHTITGAAR", "length": 1322 }, "evidence": [ { "id": "G3MZW4", "url": "https://omabrowser.org/oma/group/G3MZW4/", "database": "OMA" } ], "glygen_name": "Zebrafish", "common_name": "Zebrafish" }, { "uniprot_canonical_ac": "G3X9F6-1", "protein_name": "SH3 domain and tetratricopeptide repeats 1", "gene_name": "Sh3tc1", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MRSFREEEEEATSEELFTMGRGPEEPRGSCSPEDQIQSVSMGLPTGQERTGSAEAEATVRGDVAPPRIVVGLAAEPPPSQMTVYPTDLTLQLLAVRRKSGLRSPSLQQALRSRLRLLENDSREVARVLGELSARLLSIHSDQDRIVVTFKTFEEIWKFSTYHALGFTHHCLENLLVDQTFWLLSPSEEEETAILMYVNKDALKQTHKNLLTQEGSIFVLCPDHRVRRTIGPKGAGKGPQTLRRASGVPLGVAILETDSSSPTPNMSSNVEAAEAEPEPLTPFHQWTLRVPWDPIDESMSGPGTPDAQLMRFGLASAIADFQGSGPEEMSFSVGDVIEILGAQVPGLPWCVGRHMASGQVGFVRTGLVSMQGPASDLESAIFLSEEERSFFRSEGHFSDEDARRLLSRTSGTDVCTTCSLDWLEEAEGEQLEQREMSLPHLNPEPHGTLQMVKNILEKCKACPDHPEAPVSWSLGGVSRRASSLDLEEPRFCLDPEDDWTDPEPLDSLLQVLNAPGYGAHFRSLYDISLPWLSTALYGFDDEEELAERLAQARGVAKKVDLSMALARLCLLLGRLCARKLKLSQARVYFEEALGALEGSFGDLSLVAAVYSSLTTVYLKQKNAEKCVQVAPKAAALLLGTPGHSCNADAELLKYALRRVICGLSPQAEARACFLLARHYTHLKQPEEALPYLERLLRLNRDAGSPQASWPEDCYLLLADIYGRKCLPHLALSCLRVSSLWTRCSLPGSLRSVDLVLQNVPGPNSQRRAGHSLPSQIAYYLRQALASLAPGTGQALRGPLYASLAQLYSHHQQYSQAIAFMSQAAEADTAAGVHPVVDRLVALAWLHMLCGNSLVAMDILKCISDAAVANKDQECVMMNMVAMALKRMGRTRQAAEGYFRALHMAYAQGHLQSQAVVLANFGALCLQAGARSLAQHYLREAVGLFSQVPSGVCGRDFTQVLLWLGQLCTRRALPQQAKCYYEWAFLVAVETDHLESQLQAVQKLCLFYSKVMPNEVRCVIYHEFQLALARKTANKVLEGQLLEAISQLYLSLGTERAYKSALDYTKRSLGIFIDLQQKEKEARAWLQAGKIYYILRQNELVDLYIQVAQNAALYTGDPKLGLELFEAAGDIFFNGTWEREKAVSFYRDRALPLAVTVGDQEVELRLCNKLVALLSALEAPQEGLEFAHEALALSITLGDRLNERVAYHRLATLHHRLGHGELAEHFFLKALSLCSSPLEFDEETLYYVKVYLVLGDIIFYDLKDPFDAAGYYQLALAAAVDLGHKKAQLKIYTRLATIYHHFLVDREMSLFFYQKARTFASELNLRRTNLVPQRFCGRAPWLAPGHPS", "length": 1346 }, "evidence": [ { "id": "G3MZW4", "url": "https://omabrowser.org/oma/group/G3MZW4/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q8TE82-1", "protein_name": "SH3 domain and tetratricopeptide repeat-containing protein 1", "gene_name": "SH3TC1", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MENLPAVTTEEPTPMGRGPVGPSGGGSTRDQVRTVVMRPSVSWEKAGPEEAKAPVRGDEAPPARVAGPAAGTPPCQMGVYPTDLTLQLLAVRRKSRLRDPGLQQTLRGQLRLLENDSREMARVLGELSARLLSIHSDQDRIVVTFKTFEEIWKFSTYHALGFTHHCLANLLMDQAFWLLLPSEEEETAIQVHVDENALRLTHESLLIQEGPFFVLCPDHHVRVMTGPRDAGNGPQALRQASGAPQGEAAPETDSSPPSPSVSSEEVAVAAAPEPLIPFHQWALRIPQDPIDDAMGGPVMPGNPLMAVGLASALADFQGSGPEEMTFRGGDLIEILGAQVPSLPWCVGRHAASGRVGFVRSSLISMQGPVSELESAIFLNEEEKSFFSEGCFSEEDARQLLRRMSGTDVCSVYSLDSVEEAETEQPQEKEIPPPCLSLEPQETLQKVKNVLEQCKTCPGCPQEPASWGLCAASSDVSLQDPEEPSFCLEAEDDWEDPEALSSLLLFLNAPGYKASFRGLYDVALPWLSSVFRSFSDEEELTGRLAQARGAAKKAGLLMALARLCFLLGRLCSRRLKLSQARVYFEEALGALEGSFGDLFLVVAVYANLASIYRKQKNREKCAQVVPKAMALLLGTPDHICSTEAEGELLQLALRRAVGGQSLQAEARACFLLARHHVHLKQPEEALPFLERLLLLHRDSGAPEAAWLSDCYLLLADIYSRKCLPHLVLSCVKVASLRTRGSLAGSLRSVNLVLQNAPQPHSLPAQTSHYLRQALASLTPGTGQALRGPLYTSLAQLYSHHGCHGPAITFMTQAVEASAIAGVRAIVDHLVALAWLHVLHGQSPVALDILQSVRDAVVASEDQEGVIANMVAVALKRTGRTRQAAESYYRALRVARDLGQQRNQAVGLANFGALCLHAGASRLAQHYLLEAVRLFSRLPLGECGRDFTHVLLQLGHLCTRQGPAQQGKGYYEWALLVAVEMGHVESQLRAVQRLCHFYSAVMPSEAQCVIYHELQLSLACKVADKVLEGQLLETISQLYLSLGTERAYKSALDYTKRSLGIFIDLQKKEKEAHAWLQAGKIYYILRQSELVDLYIQVAQNVALYTGDPNLGLELFEAAGDIFFDGAWEREKAVSFYRDRALPLAVTTGNRKAELRLCNKLVALLATLEEPQEGLEFAHMALALSITLGDRLNERVAYHRLAALQHRLGHGELAEHFYLKALSLCNSPLEFDEETLYYVKVYLVLGDIIFYDLKDPFDAAGYYQLALAAAVDLGNKKAQLKIYTRLATIYHNFLLDREKSLFFYQKARTFATELNVRRVNLPPLPLCGWAPWLAPSHPR", "length": 1336 }, "evidence": [ { "id": "G3MZW4", "url": "https://omabrowser.org/oma/group/G3MZW4/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" } ], "go_annotation": {}, "pro_annotation": [], "site_annotation": [ { "start_pos": 1129, "end_pos": 1131, "annotation": "n_glycosylation_sequon" }, { "start_pos": 125, "end_pos": 127, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "G3MZW4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3MZW4" }, { "id": "PS50002", "database": "PROSITE", "url": "https://prosite.expasy.org/PS50002" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "SH3", "eco_id": "ECO_0000259", "start_pos": 309, "end_pos": 372, "start_aa": "Met", "end_aa": "Gln", "glycosite_overlap": [] } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" }, { "name": "homologset.oma", "label": "OMA Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 1129, "end_pos": 1131 }, { "start_pos": 125, "end_pos": 127 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ], "tool_support": { "graph_view": "yes" } }, { "uniprot_canonical_ac": "F6S1Q9-1", "uniprot_ac": "F6S1Q9", "uniprot_id": "F6S1Q9_BOVIN", "mass": { "chemical_mass": 73711.0, "monoisotopic_mass": 73711.0 }, "refseq": { "ac": "XP_005214872", "name": "zinc finger protein 64 isoform X1", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_005214872" }, "gene_names": [ { "name": "ZFP64", "type": "recommended", "evidence": [ { "id": "F6S1Q9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F6S1Q9" } ] }, { "name": "ZFP64", "type": "synonym", "evidence": [ { "id": "XP_005214872", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_005214872" } ] } ], "protein_names": [ { "name": "ZFP64 zinc finger protein", "type": "synonym", "evidence": [ { "id": "F6S1Q9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F6S1Q9/entry#names_and_taxonomy" } ] }, { "name": "zinc finger protein 64 isoform X1", "type": "synonym", "evidence": [ { "id": "XP_005214872", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_005214872" } ] } ], "function": [], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Bos taurus", "taxid": 9913, "evidence": [ { "database": "UniProtKB", "id": "F6S1Q9", "url": "https://www.uniprot.org/uniprotkb/F6S1Q9" } ], "common_name": "Bovine", "glygen_name": "Bovine", "reference_species": "Bos taurus [9913]" } ], "gene": [ { "name": "ZFP64", "url": "https://www.uniprot.org/uniprotkb/F6S1Q9", "locus": { "chromosome": "13", "start_pos": 79806659, "end_pos": 79882246, "strand": "+", "evidence": [ { "database": "Ensembl Gene", "id": "ENSBTAG00000001512", "url": "https://www.ensembl.org/id/ENSBTAG00000001512" } ] } } ], "crossref": [ { "id": "F6S1Q9", "url": "https://alphafold.ebi.ac.uk/entry/F6S1Q9", "database": "AlphaFoldDB", "categories": [] }, { "id": "ENSBTAG00000053699", "url": "https://bgee.org/?page=gene&gene_id=ENSBTAG00000053699", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "539018", "url": "https://www.ncbi.nlm.nih.gov/gene/539018", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR013087", "url": "https://www.ebi.ac.uk/interpro/entry/IPR013087", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR036236", "url": "https://www.ebi.ac.uk/interpro/entry/IPR036236", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR050589", "url": "https://www.ebi.ac.uk/interpro/entry/IPR050589", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR050636", "url": "https://www.ebi.ac.uk/interpro/entry/IPR050636", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "A0A3Q1LU96", "url": "https://www.orthodb.org/?gene=A0A3Q1LU96", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR24404", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR24404", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR24404:SF106", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR24404:SF106", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR47772", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR47772", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR47772:SF13", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR47772:SF13", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00096", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00096", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "XP_005214872", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_005214872", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A3Q1LU96", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1LU96", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A3Q1LU96-1", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1LU96-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0AAA9SQK7", "url": "https://www.uniprot.org/uniprotkb/A0AAA9SQK7", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0AAA9SQK7-1", "url": "https://www.uniprot.org/uniprotkb/A0AAA9SQK7-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "F6S1Q9", "url": "https://www.uniprot.org/uniprotkb/F6S1Q9", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "F6S1Q9-1", "url": "https://www.uniprot.org/uniprotkb/F6S1Q9-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MNASNEGESFPGSVQIPGGTTVLVELTPDIHICGICKQQFNNLDAFVAHKQSGCQLTGTSGAAPSTVQFVSEETVPATQTQTTTRTITSETQTITVSAPEFVFEHGYQTYLPTESNQNQTATVISLPAKSRAKKPTAPPAQKRLNCCYPGCQFKTAYGMKDMERHLKIHTGDKPHKCEVCGKCFSRKDKLKTHTRCHTGVKPYKCKSCDYAAADSSSLNKHLRIHSDERPFKCQLCPYASRNSSQLTVHLRSHTGDAPFQCWLCSAKFKISSDLKRHMRVHSGEKPFKCEFCSVRCTMKGNLKSHIRIKHSGNSFKCPHCDFLGDSKATLRKHSRLHQAEHPEKCPDCSYSCPSKAALRVHSRVHCPDRPFKCSHCSFDTKQPSNLAKHVKKFHGDALKSEAAERRDVGRSSGRQAAKLDAKKTFHCDRCDASFMREDSLRSHKRQHSEYGDGKGADVTVLQFQVDAGKPPAAPLAVGHLQVPLPPTPAPQFSEGRVKIIVGHQVPQASTIVQAAAAAVNIVQPTLVAPNPEELRGNSRLQILRQVNLIAPPPPSGCSSEAAALPQPAVLLTTHDQTEGATLHQTLIPTTPGGPQEGSGNQTFITSSGITCTDFEGLNALIQEGAAEVTVVSDGGQSIAVATTAPPIFSTSQQELPKQTYSIIQGGAHPALLCPADSIPD", "length": 680, "header": "tr|F6S1Q9-1|F6S1Q9_BOVIN Isoform 1 of ZFP64 zinc finger protein OS=Bos taurus OX=9913 GN=ZFP64 PE=3 SV=1 CANONICAL=F6S1Q9-1" }, "isoforms": [ { "isoform_ac": "A0A3Q1LU96-1", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1LU96/entry", "sequence": { "sequence": "MNASNEGESFPGSVQIPGGTTVLVELTPDIHICGICKQQFNNLDAFVAHKQSGCQLTGTSGAAPSTVQFVSEETVPATQTQTTTRTITSETQTITVSAPEFVFEHGYQTYLPTESNQNQTATVISLPAKSRAKKPTAPPAQKRLNCCYPGCQFKTAYGMKDMERHLKIHTGDKPHKCEVCGKCFSRKDKLKTHTRCHTGVKPYKCKSCDYAAADSSSLNKHLRIHSDERPFKCQLCPYASRNSSQLTVHLRSHTDNDVPKPPCPSADGSDAQKAPVAALPSESKEPTATLGERTFNCCYPGCHFKTVHGMKDLDRHLRIHTGDKPHKCEFCDKCFSRKDNLTMHMRCHTSVKPHKCHLCDYAAVDSSSLKKHLRIHSDERPYKCQLCPYASRNSSQLTVHLRSHTGDTPFQCWLCSAKFKISSDLKRHMIVHSGEKPFKCEFCDVRCTMKANLKSHIRIKHTFKCLHCAFQGRDRADLLEHSRLHQAEHPEKCPECSYSCSSAAALRVHSRVHCPDRPFKCDFCSFDTKRPSSLAKHIDKAHRDEARTENRAPPGREGPREGGGPPVAKIVTHRAFRCETCGAAFVRDDSLRCHRKQHSDHGENQSSGLVTFPPESSAPGQLGALVSVGQLEAPLESSQCL", "length": 641, "header": "tr|A0A3Q1LU96-1|F6S1Q9_BOVIN Computationally mapped isoform of ZFP64 zinc finger protein OS=Bos taurus OX=9913 GN=ZFP64 PE=3 SV=2 CANONICAL=F6S1Q9-1" }, "locus": { "chromosome": "13", "start_pos": 79882047, "end_pos": 79807413, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000080547.2", "url": "https://www.ensembl.org/id/ENSBTAT00000080547.2" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000064086.2", "url": "https://www.ensembl.org/id/ENSBTAP00000064086.2" } ] } }, { "isoform_ac": "A0AAA9SQK7-1", "url": "https://www.uniprot.org/uniprotkb/A0AAA9SQK7/entry", "sequence": { "sequence": "MNASNEGESFPGSVQIPGGTTVLVELTPDIHICGICKQQFNNLDAFVAHKQSGCQLTGTSGAAPSTVQFVSEETVPATQTQTTTRTITSETQTITGCQFKTAYGMKDMERHLKIHTGDKPHKCEVCGKCFSRKDKLKTHTRCHTGVKPYKCKSCDYAAADSSSLNKHLRIHSDERPFKCQLCPYASRNSSQLTVHLRSHTGDAPFQCWLCSAKFKISSDLKRHMRVHSGEKPFKCEFCSVRCTMKGNLKSHIRIKHSGNSFKCPHCDFLGDSKATLRKHSRLHQAEHPEKCPDCSYSCPSKAALRVHSRVHCPDRPFKCSHCSFDTKQPSNLAKHVKKFHGDALKSEAAERRDVGRSSGRQAAKLDAKKTFHCDRCDASFMREDSLRSHKRQHSEYGDGKGADVTVLQFQVDAGKPPAAPLAVGHLQVPLPPTPAPQFSEGRVKIIVGHQVPQASTIVQAAAAAVNIVQPTLVAPNPEELRGNSRLQILRQVNLIAPPPPSGCSSEAAALPQPAVLLTTHDQTEGATLHQTLIPTTPGGPQEGSGNQTFITSSGITCTDFEGLNALIQEGAAEVTVVSDGGQSIAVATTAPPIFSTSQQELPKQTYSIIQGGAHPALLCPADSIPD", "length": 626, "header": "tr|A0AAA9SQK7-1|F6S1Q9_BOVIN Computationally mapped isoform of ZFP64 zinc finger protein OS=Bos taurus OX=9913 GN=ZFP64 PE=3 SV=1 CANONICAL=F6S1Q9-1" }, "locus": { "chromosome": "13", "start_pos": 79882047, "end_pos": 79848420, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000090374.1", "url": "https://www.ensembl.org/id/ENSBTAT00000090374.1" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000086315.1", "url": "https://www.ensembl.org/id/ENSBTAP00000086315.1" } ] } }, { "isoform_ac": "F6S1Q9-1", "url": "https://www.uniprot.org/uniprotkb/F6S1Q9/entry", "sequence": { "sequence": "MNASNEGESFPGSVQIPGGTTVLVELTPDIHICGICKQQFNNLDAFVAHKQSGCQLTGTSGAAPSTVQFVSEETVPATQTQTTTRTITSETQTITVSAPEFVFEHGYQTYLPTESNQNQTATVISLPAKSRAKKPTAPPAQKRLNCCYPGCQFKTAYGMKDMERHLKIHTGDKPHKCEVCGKCFSRKDKLKTHTRCHTGVKPYKCKSCDYAAADSSSLNKHLRIHSDERPFKCQLCPYASRNSSQLTVHLRSHTGDAPFQCWLCSAKFKISSDLKRHMRVHSGEKPFKCEFCSVRCTMKGNLKSHIRIKHSGNSFKCPHCDFLGDSKATLRKHSRLHQAEHPEKCPDCSYSCPSKAALRVHSRVHCPDRPFKCSHCSFDTKQPSNLAKHVKKFHGDALKSEAAERRDVGRSSGRQAAKLDAKKTFHCDRCDASFMREDSLRSHKRQHSEYGDGKGADVTVLQFQVDAGKPPAAPLAVGHLQVPLPPTPAPQFSEGRVKIIVGHQVPQASTIVQAAAAAVNIVQPTLVAPNPEELRGNSRLQILRQVNLIAPPPPSGCSSEAAALPQPAVLLTTHDQTEGATLHQTLIPTTPGGPQEGSGNQTFITSSGITCTDFEGLNALIQEGAAEVTVVSDGGQSIAVATTAPPIFSTSQQELPKQTYSIIQGGAHPALLCPADSIPD", "length": 680, "header": "tr|F6S1Q9-1|F6S1Q9_BOVIN Isoform 1 of ZFP64 zinc finger protein OS=Bos taurus OX=9913 GN=ZFP64 PE=3 SV=1 CANONICAL=F6S1Q9-1" }, "locus": { "chromosome": "13", "start_pos": 79882047, "end_pos": 79848420, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000001981.6", "url": "https://www.ensembl.org/id/ENSBTAT00000001981.6" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000001981.5", "url": "https://www.ensembl.org/id/ENSBTAP00000001981.5" } ] } } ], "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "other", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 487, "start_aa": "Thr", "end_pos": 487, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr487", "evidence": [ { "id": "", "database": "GlyGen", "url": "https://data.glygen.org/" } ], "filter_code": "000000000000000010000.00000000001000.0.01000" } ], "phosphorylation": [], "glycation": [], "keywords": [ "glycoprotein", "glycoprotein_predicted" ], "publication": [], "pathway": [], "orthologs": [], "go_annotation": { "categories": [ { "name": "Molecular Function", "total": 4, "go_terms": [ { "name": "DNA-binding transcription factor activity", "id": "GO:0003700", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003700", "evidence": [ { "database": "UniProtKB", "id": "F6S1Q9", "url": "https://www.uniprot.org/uniprotkb/F6S1Q9" } ], "pmid": "" }, { "name": "zinc ion binding", "id": "GO:0008270", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008270", "evidence": [ { "database": "UniProtKB", "id": "F6S1Q9", "url": "https://www.uniprot.org/uniprotkb/F6S1Q9" } ], "pmid": "" }, { "name": "transcription cis-regulatory region binding", "id": "GO:0000976", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000976", "evidence": [ { "database": "UniProtKB", "id": "F6S1Q9", "url": "https://www.uniprot.org/uniprotkb/F6S1Q9" } ], "pmid": "" }, { "name": "DNA binding", "id": "GO:0003677", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003677", "evidence": [ { "database": "UniProtKB", "id": "F6S1Q9", "url": "https://www.uniprot.org/uniprotkb/F6S1Q9" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 2, "go_terms": [ { "name": "nucleus", "id": "GO:0005634", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005634", "evidence": [ { "database": "UniProtKB", "id": "F6S1Q9", "url": "https://www.uniprot.org/uniprotkb/F6S1Q9" } ], "pmid": "" }, { "name": "cytoplasm", "id": "GO:0005737", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005737", "evidence": [ { "database": "UniProtKB", "id": "F6S1Q9", "url": "https://www.uniprot.org/uniprotkb/F6S1Q9" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 3, "go_terms": [ { "name": "DNA-templated transcription", "id": "GO:0006351", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006351", "evidence": [ { "database": "UniProtKB", "id": "F6S1Q9", "url": "https://www.uniprot.org/uniprotkb/F6S1Q9" } ], "pmid": "" }, { "name": "regulation of DNA-templated transcription", "id": "GO:0006355", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006355", "evidence": [ { "database": "UniProtKB", "id": "F6S1Q9", "url": "https://www.uniprot.org/uniprotkb/F6S1Q9" } ], "pmid": "" }, { "name": "mesenchymal cell differentiation", "id": "GO:0048762", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0048762", "evidence": [ { "database": "UniProtKB", "id": "F6S1Q9", "url": "https://www.uniprot.org/uniprotkb/F6S1Q9" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 118, "end_pos": 120, "annotation": "n_glycosylation_sequon" }, { "start_pos": 242, "end_pos": 244, "annotation": "n_glycosylation_sequon" }, { "start_pos": 2, "end_pos": 4, "annotation": "n_glycosylation_sequon" }, { "start_pos": 600, "end_pos": 602, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "F6S1Q9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F6S1Q9" }, { "id": "PS50157", "database": "PROSITE", "url": "https://prosite.expasy.org/PS50157" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "C2H2-type", "eco_id": "ECO_0000259", "start_pos": 175, "end_pos": 202, "start_aa": "His", "end_aa": "Pro", "glycosite_overlap": [] } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [ 487 ], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 118, "end_pos": 120 }, { "start_pos": 242, "end_pos": 244 }, { "start_pos": 2, "end_pos": 4 }, { "start_pos": 600, "end_pos": 602 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 1 }, { "field": "total_sites", "count": 1 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 1 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "exact_sites", "count": 1 }, { "field": "exact_o_linked_sites", "count": 1 }, { "field": "fuzzy_sites", "count": 0 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_pos", "start_aa", "end_pos", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 1 }, { "field": "total_sites", "count": 1 }, { "field": "n_linked_sites", "count": 0 }, { "field": 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"sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ], "tool_support": { "graph_view": "yes" } }, { "uniprot_canonical_ac": "F6RL11-1", "uniprot_ac": "F6RL11", "uniprot_id": "F6RL11_BOVIN", "mass": { "chemical_mass": 72869.0, "monoisotopic_mass": 72869.0 }, "refseq": {}, "gene_names": [ { "name": "HIF3A", "type": "recommended", "evidence": [ { "id": 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"start_pos": 53590521, "end_pos": 53558986, "strand": "-", "evidence": [ { "database": "Ensembl Gene", "id": "ENSBTAG00000018948", "url": "https://www.ensembl.org/id/ENSBTAG00000018948" } ] } } ], "crossref": [ { "id": "F6RL11", "url": "https://alphafold.ebi.ac.uk/entry/F6RL11", "database": "AlphaFoldDB", "categories": [] }, { "id": "ENSBTAG00000018948", "url": "https://bgee.org/?page=gene&gene_id=ENSBTAG00000018948", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "cd00130", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd00130", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "cd19729", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd19729", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "507699", "url": "https://www.ncbi.nlm.nih.gov/gene/507699", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR000014", "url": 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"id": "A0A3Q1LUX8", "url": "https://www.orthodb.org/?gene=A0A3Q1LUX8", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A3Q1MKG5", "url": "https://www.orthodb.org/?gene=A0A3Q1MKG5", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "F6RL11", "url": "https://www.orthodb.org/?gene=F6RL11", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR23043", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR23043", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR23043:SF18", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR23043:SF18", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00989", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00989", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF11413", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF11413", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF14598", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF14598", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF23171", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF23171", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "R-BTA-1234158", "url": "https://www.reactome.org/PathwayBrowser/#R-BTA-1234158", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "R-BTA-1234176", "url": "https://www.reactome.org/PathwayBrowser/#R-BTA-1234176", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "R-BTA-8951664", "url": "https://www.reactome.org/PathwayBrowser/#R-BTA-8951664", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "A0A3Q1LUX8", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1LUX8", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A3Q1LUX8-1", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1LUX8-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A3Q1MKG5", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1MKG5", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A3Q1MKG5-1", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1MKG5-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0AAA9S031", "url": "https://www.uniprot.org/uniprotkb/A0AAA9S031", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0AAA9S031-1", "url": "https://www.uniprot.org/uniprotkb/A0AAA9S031-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "F6RL11", "url": "https://www.uniprot.org/uniprotkb/F6RL11", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "F6RL11-1", "url": "https://www.uniprot.org/uniprotkb/F6RL11-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MALGLQRARSSTELRKEKSRDAARSRRSQETEVLYQLAHTLPFARGVSAHLDKASIMRLTISYLRMHRLCTAGEWNQVGAGGEPLDACYLKALEGFVMVLTAEGDMAYLSENVSKHLGLSQLELIGHNIFDFIHPCDQEELQDALTPRQSLSKKKPEAPTERCFSLRMKSTLSSRGRTLNLKAATWKVLHCSGHMRVYKPPAQTSPAGSPNLEPPLQCLVLICEAIPHPGSLEPPLGRGAFLSRHSLDMKFTYCDERIAEVAGYSPDDLIGCSAYEYIHALDSDAVGQSIHTLLSKGQAVTGQYRFLARSGGYLWTQTQATVVSGGRGPQSESIVCVHFLISRVEETEVVLSLEQTERHSRRHVQRGSPSQKDAPNPGDRLDTSGPRILAFVHPPALSEAALAADPRRFCSPDLRRLLAPILDGTSVAATPSAPPATRRPQSPLPADLPDDLLVDVENAHKVLASGKDLQTVETDLDIAQDVDALDLEMLAPYISMDDDFQLNSSEQLPRAYHRPPGAVPRPRARSFHGMSPPTPETSLLPRWGSDPRLSCSSPSRGDPSASSPMVGARKRALIPSSEDEAEKVELLGIRPPKRSPSLEPENFLLPPLSLSFLLTGGPAPGSRQDPSTHLVELNEPLGPGPSLLSLYPDEDTAQPRSHFQLAAGLAQAN", "length": 669, "header": "tr|F6RL11-1|F6RL11_BOVIN Isoform 1 of Hypoxia-inducible factor 3-alpha OS=Bos taurus OX=9913 GN=HIF3A PE=4 SV=1 CANONICAL=F6RL11-1" }, "isoforms": [ { "isoform_ac": "A0A3Q1LUX8-1", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1LUX8/entry", "sequence": { "sequence": "MRPAAGAARRPRCCTSWRTRCPSRAGSAPTWTRPPSCASPSATCACTASAPQLELIGHNIFDFIHPCDQEELQDALTPRQSLSKKKPEAPTERCFSLRMKSTLSSRGRTLNLKAATWKVLHCSGHMRVYKPPAQTSPAGSPNLEPPLQCLVLICEAIPHPGSLEPPLGRGAFLSRHSLDMKFTYCDERIAEVAGYSPDDLIGCSAYEYIHALDSDAVGQSIHTLLSKGQAVTGQYRFLARSGGYLWTQTQATVVSGGRGPQSESIVCVHFLISRVEETEVVLSLEQTERHSRRHVQRGSPSQKDAPNPGDRLDTSGPRILAFVHPPALSEAALAADPRRFCSPDLRRLLAPILDGTSVAATPSAPPATRRPQSPLPADLPDDLLVDVENAHKVLASGKDLQTVETDLDIAQDPSTHLVELNEPL", "length": 424, "header": "tr|A0A3Q1LUX8-1|F6RL11_BOVIN Computationally mapped isoform of Hypoxia-inducible factor 3-alpha OS=Bos taurus OX=9913 GN=HIF3A PE=4 SV=2 CANONICAL=F6RL11-1" }, "locus": { "chromosome": "18", "start_pos": 53586275, "end_pos": 53565219, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000077826.2", "url": "https://www.ensembl.org/id/ENSBTAT00000077826.2" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000059056.2", "url": "https://www.ensembl.org/id/ENSBTAP00000059056.2" } ] } }, { "isoform_ac": "A0A3Q1MKG5-1", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1MKG5/entry", "sequence": { "sequence": "MWQHPTCLPHPTLSLPGAPPVNAGHARRSSTELRKEKSRDAARSRRSQETEVLYQLAHTLPFARGVSAHLDKASIMRLTISYLRMHRLCTAGEWNQVGAGGEPLDACYLKALEGFVMVLTAEGDMAYLSENVSKHLGLSQLELIGHNIFDFIHPCDQEELQDALTPRQSLSKKKPEAPTERCFSLRMKSTLSSRGRTLNLKAATWKVLHCSGHMRVYKPPAQTSPAGSPNLEPPLQCLVLICEAIPHPGSLEPPLGRGAFLSRHSLDMKFTYCDERIAEVAGYSPDDLIGCSAYEYIHALDSDAVGQSIHTLLSKGQAVTGQYRFLARSGGYLWTQTQATVVSGGRGPQSESIVCVHFLISRVEETEVVLSLEQTERHSRRHVQRGSPSQKDAPNPGDRLDTSGPRILAFVHPPALSEAALAADPRRFCSPDLRRLLAPILDGTSVAATPSAPPATRRPQSPLPADLPDDLLVDVENAHKVLASGKDLQTVETDLDIAQDVDALDLEMLAPYISMDDDFQLNSSEQLPRAYHRPPGAVPRPRARSFHGMSPPTPETSLLPRWGSDPRLSCSSPSRGDPSASSPMVGARKRALIPSSEDEAEKVELLGIRPPKRSPSLEPENFLLPPLSLSFLLTGGPAPGSRQDPSTHLVELNEPLGPGPSLLSLYPDEDTAQPRSHFQLAAGLAQAN", "length": 688, "header": "tr|A0A3Q1MKG5-1|A0A3Q1MKG5_BOVIN Computationally mapped isoform of Hypoxia-inducible factor 3-alpha OS=Bos taurus OX=9913 GN=HIF3A PE=4 SV=1 CANONICAL=F6RL11-1" }, "locus": { "chromosome": "18", "start_pos": 53587797, "end_pos": 53565101, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000077844.2", "url": "https://www.ensembl.org/id/ENSBTAT00000077844.2" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000071359.1", "url": "https://www.ensembl.org/id/ENSBTAP00000071359.1" } ] } }, { "isoform_ac": "A0AAA9S031-1", "url": "https://www.uniprot.org/uniprotkb/A0AAA9S031/entry", "sequence": { "sequence": "MRPAAGAARRPRCCTSWRTRCPSRAGSAPTWTRPPSCASPSATCACTASAPQLELIGHNIFDFIHPCDQEELQDALTPRQSLSKKKPEAPTERCFSLRMKSTLSSRGRTLNLKAATWKVLHCSGHMRVYKPPAQTSPAGSPNLEPPLQCLVLICEAIPHPGSLEPPLGRGAFLSRHSLDMKFTYCDERIAEVAGYSPDDLIGCSAYEYIHALDSDAVGQSIHTLLSKGQAVTGQYRFLARSGGYLWTQTQATVVSGGRGPQSESIVCVHFLISRVEETEVVLSLEQTERHSRRHVQRGSPSQKDAPNPGDRLDTSGPRILAFVHPPALSEAALAADPRRFCSPDLRRLLAPILDGTSVAATPSAPPATRRPQSPLPADLPDDLLVDVENAHKVLASGKDLQTVETDLDIAQDVDALDLEMLAPYISMDDDFQLNSSEQLPRAYHRPPGAVPRPRARSFHGMSPPTPETSLLPRWGSDPRLSCSSPSRGDPSASSPMVGARKRALIPSSEDEAEKVELLGIRPPKRSPSLEPENFLLPPLSLSFLLTGGPAPGSRQDPSTHLVELNEPLGPGPSLLSLYPDEDTAQPRSHFQLAAGLAQAN", "length": 600, "header": "tr|A0AAA9S031-1|F6RL11_BOVIN Computationally mapped isoform of Hypoxia-inducible factor 3-alpha OS=Bos taurus OX=9913 GN=HIF3A PE=4 SV=1 CANONICAL=F6RL11-1" }, "locus": { "chromosome": "18", "start_pos": 53587797, "end_pos": 53565219, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000116112.1", "url": "https://www.ensembl.org/id/ENSBTAT00000116112.1" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000079209.1", "url": "https://www.ensembl.org/id/ENSBTAP00000079209.1" } ] } }, { "isoform_ac": "F6RL11-1", "url": "https://www.uniprot.org/uniprotkb/F6RL11/entry", "sequence": { "sequence": "MALGLQRARSSTELRKEKSRDAARSRRSQETEVLYQLAHTLPFARGVSAHLDKASIMRLTISYLRMHRLCTAGEWNQVGAGGEPLDACYLKALEGFVMVLTAEGDMAYLSENVSKHLGLSQLELIGHNIFDFIHPCDQEELQDALTPRQSLSKKKPEAPTERCFSLRMKSTLSSRGRTLNLKAATWKVLHCSGHMRVYKPPAQTSPAGSPNLEPPLQCLVLICEAIPHPGSLEPPLGRGAFLSRHSLDMKFTYCDERIAEVAGYSPDDLIGCSAYEYIHALDSDAVGQSIHTLLSKGQAVTGQYRFLARSGGYLWTQTQATVVSGGRGPQSESIVCVHFLISRVEETEVVLSLEQTERHSRRHVQRGSPSQKDAPNPGDRLDTSGPRILAFVHPPALSEAALAADPRRFCSPDLRRLLAPILDGTSVAATPSAPPATRRPQSPLPADLPDDLLVDVENAHKVLASGKDLQTVETDLDIAQDVDALDLEMLAPYISMDDDFQLNSSEQLPRAYHRPPGAVPRPRARSFHGMSPPTPETSLLPRWGSDPRLSCSSPSRGDPSASSPMVGARKRALIPSSEDEAEKVELLGIRPPKRSPSLEPENFLLPPLSLSFLLTGGPAPGSRQDPSTHLVELNEPLGPGPSLLSLYPDEDTAQPRSHFQLAAGLAQAN", "length": 669, "header": "tr|F6RL11-1|F6RL11_BOVIN Isoform 1 of Hypoxia-inducible factor 3-alpha OS=Bos taurus OX=9913 GN=HIF3A PE=4 SV=1 CANONICAL=F6RL11-1" }, "locus": { "chromosome": "18", "start_pos": 53587797, "end_pos": 53559001, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000025217.7", "url": "https://www.ensembl.org/id/ENSBTAT00000025217.7" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000025217.6", "url": "https://www.ensembl.org/id/ENSBTAP00000025217.6" } ] } } ], "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "other", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 430, "start_aa": "Thr", "end_pos": 430, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr430", "evidence": [ { "id": "", "database": "GlyGen", "url": "https://data.glygen.org/" } ], "filter_code": "000000000000000010000.00000000001000.0.01000" }, { "glytoucan_ac": "", "type": "O-linked", "subtype": "other", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 534, "start_aa": "Thr", "end_pos": 534, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr534", "evidence": [ { "id": "", "database": "GlyGen", "url": "https://data.glygen.org/" } ], "filter_code": "000000000000000010000.00000000001000.0.01000" } ], "phosphorylation": [], "glycation": [], "keywords": [ "glycoprotein", "glycoprotein_predicted" ], "publication": [], "pathway": [ { "id": "R-BTA-1234158", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-BTA-1234158", "resource": "Reactome", "description": "Regulation of gene expression by Hypoxia-inducible Factor" }, { "id": "R-BTA-1234176", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-BTA-1234176", "resource": "Reactome", "description": "Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha" }, { "id": "R-BTA-8951664", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-BTA-8951664", "resource": "Reactome", "description": "Neddylation" } ], "orthologs": [ { "uniprot_canonical_ac": "Q0VBL6-1", "protein_name": "Hypoxia-inducible factor 3-alpha", "gene_name": "Hif3a", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MDWDQDRSNTELRKEKSRDAARSRRSQETEVLYQLAHTLPFARGVSAHLDKASIMRLTISYLRMHRLCAAGEWNQVEKGGEPLDACYLKALEGFVMVLTAEGDMAYLSENVSKHLGLSQLELIGHSIFDFIHPCDQEELQDALTPRPNLSKKKLEAPTERHFSLRMKSTLTSRGRTLNLKAATWKVLHCSGHMRAYKPPAQTSPAGSPRSEPPLQCLVLICEAIPHPASLEPPLGRGAFLSRHSLDMKFTYCDERIAEVAGYSPDDLIGCSAYEYIHALDSDAVSRSIHTLLSKGQAVTGQYRFLARTGGYLWTQTQATVVSGGRGPQSESIICVHFLISRVEETGVVLSLEQTEQHTRRPPRLSASSQKGIPGNSVDSPAPRILAFLHPPALSEASLAADPRRFCSPDLRRLMAPILDGPPPAATPSTPQATRRPQSPLPADLPDKLTVGLENAHRLSTAQKNKTVETDLDIAQDPDTLDLEMLAPYISMDDDFQLNSSEQLPKVHRRPPRVARRPRARSFHGLSPPIPEPSLLPRWGSDPRLNCSSPSRGDRPTASLMPGTRKRALAQSSEDKGLELLETKPPKRSPRLEPGSFLLPPLSLSFLLQGRQLPGNQQDPRAPLVHSHEPLGLAPSLLSLCQHEETVQPRNRFPPAAGLGQTH", "length": 662 }, "evidence": [ { "id": "F6RL11", "url": "https://omabrowser.org/oma/group/F6RL11/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q9JHS2-1", "protein_name": "Hypoxia-inducible factor 3-alpha", "gene_name": "Hif3a", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MDWDQDRSSTELRKEKSRDAARSRRSQETEVLYQLAHTLPFARGVSAHLDKASIMRLTISYLRMHRLCAAGEWNQVRKEGEPLDACYLKALEGFVMVLTAEGDMAYLSENVSKHLGLSQLELIGHSIFDFIHPCDQEELQDALTPRPSLSKKKSEAATGRHFSLRMKSTLTSRGRALNLKAATWKVLHCSGHMRAYKPPAQTSPAGSPRSEPPLQCLVLICEAIPHPASLEPPLGRGAFLSRHSLDMKFTYCDERIAEVAGYSPDDLIGCSAYEYIHALDSDAVSRSIHTLLSKGQAVTGQYRFLARTGGYLWTQTQATVVSGGRGPQSESIICVHFLISRVEENGVVLSLEQTEQHTRRPPQLGTSSKKGIPGNSLDPPAPRILAFLHPPALSEASLAADPRRFCSPDLRRLMAPILDGPPTAATPSTPQAARRPQSPLPADLPDQLAVGLENAHRLSTARKNKTMETDLDIAQDPDTPDLEMLAPYISMDDDFQLNSSEQLPKVHRRPPRTARRPRARSFHGLSPPIPEATLLPRWGSDPRLNCSSPSKGDPPTAPLTPRTRKRALAQSSEDKGLELLETKPPKRSPRLEPGSVLLPPLSLSFLLQGRQLPGNQPDPRAPLVDSHEPLGLAPSLLSLYQHEETIQSRNHFLPAAGLAQTH", "length": 662 }, "evidence": [ { "id": "F6RL11", "url": "https://omabrowser.org/oma/group/F6RL11/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "Q9Y2N7-1", "protein_name": "Hypoxia-inducible factor 3-alpha", "gene_name": "HIF3A", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MALGLQRARSTTELRKEKSRDAARSRRSQETEVLYQLAHTLPFARGVSAHLDKASIMRLTISYLRMHRLCAAGEWNQVGAGGEPLDACYLKALEGFVMVLTAEGDMAYLSENVSKHLGLSQLELIGHSIFDFIHPCDQEELQDALTPQQTLSRRKVEAPTERCFSLRMKSTLTSRGRTLNLKAATWKVLNCSGHMRAYKPPAQTSPAGSPDSEPPLQCLVLICEAIPHPGSLEPPLGRGAFLSRHSLDMKFTYCDDRIAEVAGYSPDDLIGCSAYEYIHALDSDAVSKSIHTLLSKGQAVTGQYRFLARSGGYLWTQTQATVVSGGRGPQSESIVCVHFLISQVEETGVVLSLEQTEQHSRRPIQRGAPSQKDTPNPGDSLDTPGPRILAFLHPPSLSEAALAADPRRFCSPDLRRLLGPILDGASVAATPSTPLATRHPQSPLSADLPDELPVGTENVHRLFTSGKDTEAVETDLDIAQDADALDLEMLAPYISMDDDFQLNASEQLPRAYHRPLGAVPRPRARSFHGLSPPALEPSLLPRWGSDPRLSCSSPSRGDPSASSPMAGARKRTLAQSSEDEDEGVELLGVRPPKRSPSPEHENFLLFPLSLSFLLTGGPAPGSLQDPSTPLLNLNEPLGLGPSLLSPYSDEDTTQPGGPFQPRAGSAQAD", "length": 669 }, "evidence": [ { "id": "F6RL11", "url": "https://omabrowser.org/oma/group/F6RL11/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" } ], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 6, "go_terms": [ { "name": "nucleus", "id": "GO:0005634", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005634", "evidence": [ { "database": "UniProtKB", "id": "F6RL11", "url": "https://www.uniprot.org/uniprotkb/F6RL11" } ], "pmid": "" }, { "name": "mitochondrion", "id": "GO:0005739", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005739", "evidence": [ { "database": "UniProtKB", "id": "F6RL11", "url": "https://www.uniprot.org/uniprotkb/F6RL11" } ], "pmid": "" }, { "name": "transcription regulator complex", "id": "GO:0005667", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005667", "evidence": [ { "database": "UniProtKB", "id": "F6RL11", "url": "https://www.uniprot.org/uniprotkb/F6RL11" } ], "pmid": "" }, { "name": "nucleoplasm", "id": "GO:0005654", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005654", "evidence": [ { "database": "UniProtKB", "id": "F6RL11", "url": "https://www.uniprot.org/uniprotkb/F6RL11" } ], "pmid": "" }, { "name": "cytosol", "id": "GO:0005829", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005829", "evidence": [ { "database": "UniProtKB", "id": "F6RL11", "url": "https://www.uniprot.org/uniprotkb/F6RL11" } ], "pmid": "" }, { "name": "chromatin", "id": "GO:0000785", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000785", "evidence": [ { "database": "UniProtKB", "id": "F6RL11", "url": "https://www.uniprot.org/uniprotkb/F6RL11" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 7, "go_terms": [ { "name": "DNA-templated transcription", "id": "GO:0006351", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006351", "evidence": [ { "database": "UniProtKB", "id": "F6RL11", "url": "https://www.uniprot.org/uniprotkb/F6RL11" } ], "pmid": "" }, { "name": "regulation of DNA-templated transcription", "id": "GO:0006355", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006355", "evidence": [ { "database": "UniProtKB", "id": "F6RL11", "url": "https://www.uniprot.org/uniprotkb/F6RL11" } ], "pmid": "" }, { "name": "angiogenesis", "id": "GO:0001525", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0001525", "evidence": [ { "database": "UniProtKB", "id": "F6RL11", "url": "https://www.uniprot.org/uniprotkb/F6RL11" } ], "pmid": "" }, { "name": "regulation of transcription by RNA polymerase II", "id": "GO:0006357", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006357", "evidence": [ { "database": "UniProtKB", "id": "F6RL11", "url": "https://www.uniprot.org/uniprotkb/F6RL11" } ], "pmid": "" }, { "name": "apoptotic process", "id": "GO:0006915", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006915", "evidence": [ { "database": "UniProtKB", "id": "F6RL11", "url": "https://www.uniprot.org/uniprotkb/F6RL11" } ], "pmid": "" }, { "name": "cellular response to hypoxia", "id": "GO:0071456", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0071456", "evidence": [ { "database": "UniProtKB", "id": "F6RL11", "url": "https://www.uniprot.org/uniprotkb/F6RL11" } ], "pmid": "" }, { "name": "intracellular oxygen homeostasis", "id": "GO:0032364", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0032364", "evidence": [ { "database": "UniProtKB", "id": "F6RL11", "url": "https://www.uniprot.org/uniprotkb/F6RL11" } ], "pmid": "" } ] }, { "name": "Molecular Function", "total": 4, "go_terms": [ { "name": "protein dimerization activity", "id": "GO:0046983", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0046983", "evidence": [ { "database": "UniProtKB", "id": "F6RL11", "url": "https://www.uniprot.org/uniprotkb/F6RL11" } ], "pmid": "" }, { "name": "RNA polymerase II transcription regulatory region sequence-specific DNA binding", "id": "GO:0000977", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000977", "evidence": [ { "database": "UniProtKB", "id": "F6RL11", "url": "https://www.uniprot.org/uniprotkb/F6RL11" } ], "pmid": "" }, { "name": "DNA-binding transcription factor activity, RNA polymerase II-specific", "id": "GO:0000981", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000981", "evidence": [ { "database": "UniProtKB", "id": "F6RL11", "url": "https://www.uniprot.org/uniprotkb/F6RL11" } ], "pmid": "" }, { "name": "RNA polymerase II cis-regulatory region sequence-specific DNA binding", "id": "GO:0000978", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000978", "evidence": [ { "database": "UniProtKB", "id": "F6RL11", "url": "https://www.uniprot.org/uniprotkb/F6RL11" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 112, "end_pos": 114, "annotation": "n_glycosylation_sequon" }, { "start_pos": 503, "end_pos": 505, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [ { "pdb_id": "AF-F6RL11-F1", "pdb_chain": "global", "start_pos": 1, "end_pos": 669, "overlap": "1.0", "method": "AlphaFold", "type": "alphafold", "resolution": -1.0, "url": "https://data.glygen.org/ln2downloads/pdb/current/AF-F6RL11-F1.pdb", "url_external": "https://alphafold.ebi.ac.uk/entry/F6RL11" } ], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "F6RL11", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F6RL11" }, { "id": "PS50888", "database": "PROSITE", "url": "https://prosite.expasy.org/PS50888" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "BHLH", "eco_id": "ECO_0000259", "start_pos": 14, "end_pos": 67, "start_aa": "Leu", "end_aa": "His", "glycosite_overlap": [] }, { "evidence": [ { "id": "F6RL11", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F6RL11" }, { "id": "PS50112", "database": "PROSITE", "url": "https://prosite.expasy.org/PS50112" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "PAS", "eco_id": "ECO_0000259", "start_pos": 90, "end_pos": 154, "start_aa": "Leu", "end_aa": "Lys", "glycosite_overlap": [] } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" }, { "name": "homologset.oma", "label": "OMA Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [ 430, 534 ], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 112, "end_pos": 114 }, { "start_pos": 503, "end_pos": 505 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 2 }, { "field": "total_sites", "count": 2 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 2 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "exact_sites", "count": 2 }, { "field": "exact_o_linked_sites", "count": 2 }, { "field": "fuzzy_sites", "count": 0 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", 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"https://www.uniprot.org/uniprotkb/G3MZP8/entry#names_and_taxonomy" } ] }, { "name": "carboxypeptidase A4", "type": "synonym", "evidence": [ { "id": "XP_024846926", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_024846926" } ] } ], "function": [ { "annotation": "Carboxypeptidase that catalyzes the release of a C-terminal amino acid, but has little or no action with -Asp, -Glu, -Arg, -Lys or -Pro. Catalyzes the conversion of leukotriene C4 to leukotriene F4 via the hydrolysis of an amide bond.", "evidence": [ { "database": "UniProtKB", "id": "A0AAA9SBW5", "url": "https://www.uniprot.org/uniprotkb/A0AAA9SBW5#function" }, { "database": "UniProtKB", "id": "ARBA00059652", "url": "https://www.uniprot.org/uniprotkb/ARBA00059652#function" }, { "database": "UniProtKB", "id": "G3MZP8", "url": "https://www.uniprot.org/uniprotkb/G3MZP8#function" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Bos taurus", "taxid": 9913, "evidence": [ { "database": "UniProtKB", "id": "G3MZP8", "url": "https://www.uniprot.org/uniprotkb/G3MZP8" } ], "common_name": "Bovine", "glygen_name": "Bovine", "reference_species": "Bos taurus [9913]" } ], "gene": [ { "name": "CPA4", "url": "https://www.uniprot.org/uniprotkb/G3MZP8", "locus": { "chromosome": "4", "start_pos": 94070646, "end_pos": 94046070, "strand": "-", "evidence": [ { "database": "Ensembl Gene", "id": "ENSBTAG00000046648", "url": "https://www.ensembl.org/id/ENSBTAG00000046648" } ] } } ], "crossref": [ { "id": "G3MZP8", "url": "https://alphafold.ebi.ac.uk/entry/G3MZP8", "database": "AlphaFoldDB", "categories": [] }, { "id": "ENSBTAG00000046648", "url": "https://bgee.org/?page=gene&gene_id=ENSBTAG00000046648", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "cd03870", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd03870", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "101903427", "url": "https://www.ncbi.nlm.nih.gov/gene/101903427", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR000834", "url": "https://www.ebi.ac.uk/interpro/entry/IPR000834", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR003146", "url": "https://www.ebi.ac.uk/interpro/entry/IPR003146", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR034248", "url": "https://www.ebi.ac.uk/interpro/entry/IPR034248", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR036990", "url": "https://www.ebi.ac.uk/interpro/entry/IPR036990", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR057246", "url": "https://www.ebi.ac.uk/interpro/entry/IPR057246", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR057247", "url": "https://www.ebi.ac.uk/interpro/entry/IPR057247", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "G3MZP8", "url": "https://www.orthodb.org/?gene=G3MZP8", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR11705", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR11705", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR11705:SF136", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR11705:SF136", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00246", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00246", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF02244", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF02244", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "XP_024846926", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_024846926", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "50740", "url": "https://www.rhea-db.org/rhea/50740", "database": "Rhea", "categories": [ "Enzyme and Pathway" ] }, { "id": "A0A3Q1LVL9", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1LVL9", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A3Q1LVL9-1", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1LVL9-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0AAA9SBW5", "url": "https://www.uniprot.org/uniprotkb/A0AAA9SBW5", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0AAA9SBW5-1", "url": "https://www.uniprot.org/uniprotkb/A0AAA9SBW5-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "G3MZP8", "url": "https://www.uniprot.org/uniprotkb/G3MZP8", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "G3MZP8-1", "url": "https://www.uniprot.org/uniprotkb/G3MZP8-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MSLPQTPYNYSLTQPLYDWHPWNMKWILFFGALIGSGICDRETFSGHQVFRINIRNEDEISKLNRLVNSDNLKLDLWKSPSTLGHPADVLVPSFSLQEVKSFLEDHGLEYSVAIEDLQNVLDSEHQQLQRNVRQELSNNCFNYGAYHTLEDIHKEMDSIVKSYPHLVSAVKIGHSFENRLMYVLKFSTGKGRQRPAILLNAGIHAREWISSATAIWTARKIACDYGRDLVITSILEKMDIFLLPVANPDGYVYTHTHNRLWRKTRSVNPRSTCIGADPNRNWDSHFGGVGTSNDPCSDTYHGLHAHSEVEVKSVADFITNHGDFKCLIDLHSYSQLVMYPYGYTTSRVPDADELDMVARNASKAMASLSGTQYQVGSVGSTVYTASGNTIDWAYDNGIKYAFSFELRDTGFYAFALPADQIIPTAQETWLGLKTIMEHVRNNI", "length": 443, "header": "tr|G3MZP8-1|G3MZP8_BOVIN Isoform 1 of Carboxypeptidase A1 OS=Bos taurus OX=9913 GN=CPA4 PE=3 SV=4 CANONICAL=G3MZP8-1" }, "isoforms": [ { "isoform_ac": "A0A3Q1LVL9-1", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1LVL9/entry", "sequence": { "sequence": "MSLPQTPYNYSLTQPLYDWHPWNMKWILFFGALIGSGICDRETFSGHQVFRINIRNEDEISKLNRLVNSDNLKLDLWKSPSTLGHPADVLVPSFSLQEVKSFLEDHGLEYSVAIEDLQNVLDSEHQQLQRNVRQELSNNCFNYGAYHTLEDFSTGKGRQRPAILLNAGIHAREWISSATAIWTARKIACDYGRDLVITSILEKMDIFLLPVANPDGYVYTHTHNRLWRKTRSVNPRSTCIGADPNRNWDSHFGGVGTSNDPCSDTYHGLHAHSEVEVKSVADFITNHGDFKCLIDLHSYSQLVMYPYGYTTSRVPDADELDMVARNASKAMASLSGTQYQVGSVGSTVYTASGNTIDWAYDNGIKYAFSFELRDTGFYAFALPADQIIPTAQETWLGLKTIMEHVRNNI", "length": 409, "header": "tr|A0A3Q1LVL9-1|G3MZP8_BOVIN Computationally mapped isoform of Carboxypeptidase A1 OS=Bos taurus OX=9913 GN=CPA4 PE=3 SV=3 CANONICAL=G3MZP8-1" }, "locus": { "chromosome": "4", "start_pos": 94069999, "end_pos": 94046269, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000084920.3", "url": "https://www.ensembl.org/id/ENSBTAT00000084920.3" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000059366.3", "url": "https://www.ensembl.org/id/ENSBTAP00000059366.3" } ] } }, { "isoform_ac": "A0AAA9SBW5-1", "url": "https://www.uniprot.org/uniprotkb/A0AAA9SBW5/entry", "sequence": { "sequence": "MSLPQTPYNYSLTQPLYDWHPWNMKWILFFGALIGSGICDRETFSGHQVFRINIRNEDEISKLNRLVNSDNLKLDLWKSPSTLGHPADVLVPSFSLQEVKSFLEDHGLEYSVAIEDLQIHKEMDSIVKSYPHLVSAVKIGHSFENRLMYVLKFSTGKGRQRPAILLNAGIHAREWISSATAIWTARKIACDYGRDLVITSILEKMDIFLLPVANPDGYVYTHTHNRLWRKTRSVNPRSTCIGADPNRNWDSHFGGVGTSNDPCSDTYHGLHAHSEVEVKSVADFITNHGDFKCLIDLHSYSQLVMYPYGYTTSRVPDADELDMVARNASKAMASLSGTQYQVGSVGSTVYTASGNTIDWAYDNGIKYAFSFELRDTGFYAFALPADQIIPTAQETWLGLKTIMEHVRNNI", "length": 410, "header": "tr|A0AAA9SBW5-1|G3MZP8_BOVIN Computationally mapped isoform of Carboxypeptidase A1 OS=Bos taurus OX=9913 GN=CPA4 PE=3 SV=1 CANONICAL=G3MZP8-1" }, "locus": { "chromosome": "4", "start_pos": 94069999, "end_pos": 94046269, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000125682.2", "url": "https://www.ensembl.org/id/ENSBTAT00000125682.2" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000080994.1", "url": "https://www.ensembl.org/id/ENSBTAP00000080994.1" } ] } }, { "isoform_ac": "G3MZP8-1", "url": "https://www.uniprot.org/uniprotkb/G3MZP8/entry", "sequence": { "sequence": "MSLPQTPYNYSLTQPLYDWHPWNMKWILFFGALIGSGICDRETFSGHQVFRINIRNEDEISKLNRLVNSDNLKLDLWKSPSTLGHPADVLVPSFSLQEVKSFLEDHGLEYSVAIEDLQNVLDSEHQQLQRNVRQELSNNCFNYGAYHTLEDIHKEMDSIVKSYPHLVSAVKIGHSFENRLMYVLKFSTGKGRQRPAILLNAGIHAREWISSATAIWTARKIACDYGRDLVITSILEKMDIFLLPVANPDGYVYTHTHNRLWRKTRSVNPRSTCIGADPNRNWDSHFGGVGTSNDPCSDTYHGLHAHSEVEVKSVADFITNHGDFKCLIDLHSYSQLVMYPYGYTTSRVPDADELDMVARNASKAMASLSGTQYQVGSVGSTVYTASGNTIDWAYDNGIKYAFSFELRDTGFYAFALPADQIIPTAQETWLGLKTIMEHVRNNI", "length": 443, "header": "tr|G3MZP8-1|G3MZP8_BOVIN Isoform 1 of Carboxypeptidase A1 OS=Bos taurus OX=9913 GN=CPA4 PE=3 SV=4 CANONICAL=G3MZP8-1" }, "locus": { "chromosome": "4", "start_pos": 94069999, "end_pos": 94046269, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000066192.4", "url": "https://www.ensembl.org/id/ENSBTAT00000066192.4" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000055050.4", "url": "https://www.ensembl.org/id/ENSBTAP00000055050.4" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [ "enzyme" ], "publication": [], "pathway": [], "orthologs": [], "go_annotation": { "categories": [ { "name": "Biological Process", "total": 3, "go_terms": [ { "name": "proteolysis", "id": "GO:0006508", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006508", "evidence": [ { "database": "UniProtKB", "id": "G3MZP8", "url": "https://www.uniprot.org/uniprotkb/G3MZP8" } ], "pmid": "" }, { "name": "hormone catabolic process", "id": "GO:0042447", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0042447", "evidence": [ { "database": "UniProtKB", "id": "G3MZP8", "url": "https://www.uniprot.org/uniprotkb/G3MZP8" } ], "pmid": "" }, { "name": 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"RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_002688192" } ] } ], "protein_names": [ { "name": "Family with sequence similarity 184 member B", "type": "synonym", "evidence": [ { "id": "G3MYE6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3MYE6/entry#names_and_taxonomy" } ] }, { "name": "protein FAM184B isoform X1", "type": "synonym", "evidence": [ { "id": "XP_002688192", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_002688192" } ] } ], "function": [], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Bos taurus", "taxid": 9913, "evidence": [ { "database": "UniProtKB", "id": "G3MYE6", "url": "https://www.uniprot.org/uniprotkb/G3MYE6" } ], "common_name": "Bovine", "glygen_name": "Bovine", "reference_species": "Bos taurus [9913]" } ], "gene": [ { "name": "FAM184B", "url": "https://www.uniprot.org/uniprotkb/G3MYE6", "locus": { "chromosome": "6", "start_pos": 37180074, "end_pos": 37321575, "strand": "+", "evidence": [ { "database": "Ensembl Gene", "id": "ENSBTAG00000005932", "url": "https://www.ensembl.org/id/ENSBTAG00000005932" } ] } } ], "crossref": [ { "id": "G3MYE6", "url": "https://alphafold.ebi.ac.uk/entry/G3MYE6", "database": "AlphaFoldDB", "categories": [] }, { "id": "ENSBTAG00000005932", "url": "https://bgee.org/?page=gene&gene_id=ENSBTAG00000005932", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "523874", "url": "https://www.ncbi.nlm.nih.gov/gene/523874", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR039478", "url": "https://www.ebi.ac.uk/interpro/entry/IPR039478", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "bta:523874", "url": "https://www.genome.jp/dbget-bin/www_bget?bta:523874", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "PQELDCQ", "url": "https://omabrowser.org/oma/group/PQELDCQ/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "A0A3Q1M052", "url": "https://www.orthodb.org/?gene=A0A3Q1M052", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR18870", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR18870", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR18870:SF8", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR18870:SF8", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF15665", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF15665", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "XP_002688192", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_002688192", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A3Q1M052", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1M052", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A3Q1M052-1", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1M052-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "G3MYE6", "url": "https://www.uniprot.org/uniprotkb/G3MYE6", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "G3MYE6-1", "url": "https://www.uniprot.org/uniprotkb/G3MYE6-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MASALNSKIHAPGNCPASKADARGGAGWRMDCDPEMHMKMCKKIAQLTKVIYALNTRQDETEAGMEALREAHQEELQQAVAETEARLLQAQGRVGEEEALRQRIQALESALELQKQLTQEALAQSASCRLETQERELRVEAEHAERVLTLSKEMLELKADYEKRLRHLSGHEAPRWDRLTKEGPEPKAEPGCGPEMREVLLEVERLRTENQQLSKDYARKAEELQATYERENEAVRQAMQQSVSEALWQWQEKETDLRKNFQAQEAALQAQVRKLEGDLEHRGRKISDLKKYAQKLKDRIQDLDVQLKEARQENSELKSTAKKLGEKLAIAKDKLMLQECHVTQKTGDMKTERVSENKVLRKENNLEACSLHPQQDQNFAKECPCTKGGTDTQTKKEACIETEYMKQKYEEDLRKIKHQTEEEKKHLKDQLMKRLEDLVKKHTVEIKSVRSSVEAERKRLQKEVEAQLEEVKKKSENEIKQLEEEKAALSVKLQNSLLEVLRLEEFIQQNKACPPRGDEKPQELDYQHCNILETQDPCLRPNEPSQTLPRGEEYQDKLAAEEGTSSDEEERIEAPIKEGGDLQPPLGSLPKEKAPEIQRLQEEWQSQKARLQAQVSQMQQALEQCATNYREDLRELKQLSDHEREQLRHELQETIQQNQAAKAQLEAAHKRALCMLEKAKNQEVKATEERLKKESSHSLQIQHQAHRLEMQALEEKARQELQGELERMQAQQALLLESLRQELAEQRAACSEHQKDLEVLQTELRALDSMGRRQAITQCPGDSEDHAGTSEKEGGPGQAGSPKSKSAAELQPSEGCSLREENSQLKEAVKRLQAEVEQHQQEALQLRDQSRLLEEDQQAQRAREVEILRQEHRKEMQAMVADFSSAQARLQARLAALETELKDSGEKPGKGASRPEDVQLIGRLQTRLKEREEIIKQLTEERRFHYAAFPSAMSHRNRSFSFNPHPGYLTPSMKKKKMEEVPSRVVSVPNLASYAKNFLSGDLSSRINAPPITKSPSLDPGPSCGRPYKPTPSLDVQTATRTQDDDTAQPKEAQQKQGSAHQEWFTKYFSF", "length": 1071, "header": "tr|G3MYE6-1|G3MYE6_BOVIN Isoform 1 of Family with sequence similarity 184 member B OS=Bos taurus OX=9913 GN=FAM184B PE=4 SV=3 CANONICAL=G3MYE6-1" }, "isoforms": [ { "isoform_ac": "A0A3Q1M052-1", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1M052/entry", "sequence": { "sequence": "MEALREAHQEELQQAVAETEARLLQAQGRVGEEEALRQRIQALESALELQKQLTQEALAQSASCRLETQERELRVEAEHAERVLTLSKEMLELKADYEKRLRHLSGHEAPRWDRLTKEGPEPKAEPGCGPEMREVLLEVERLRTENQQLSKDYARKAEELQATYERENEAVRQAMQQSVSEALWQWQEKETDLRKNFQAQEAALQAQVRKLEGDLEHRGRKISDLKKYAQKLKDRIQDLDVQLKEARQENSELKSTAKKLGEKLAIAKDKLMLQECHVTQKTGDMKTERVSENKVLRKENNLEACSLHPQQDQNFAKECPCTKGGTDTQTKKEACIETEYMKQKYEEDLRKIKHQTEEEKKHLKDQLMKRLEDLVKKHTVEIKSVRSSVEAERKRLQKEVEAQLEEVKKKSENEIKQLEEEKAALSVKLQNSLLEVLRLEEFIQQNKACPPRGDEKPQELDYQHCNILETQDPCLRPNEPSQTLPRGEEYQDKLAAEEGTSSDEEERIEAPIKEGGDLQPPLGSLPKEKAPEIQRLQEEWQSQKARLQAQVSQMQQALEQCATNYREDLRELKQLSDHEREQLRHELQETIQQNQAAKAQLEAAHKRALCMLEKAKNQEVKATEERLKKESSHSLQIQHQAHRLEMQALEEKARQELQGELERMQAQQALLLESLRQELAEQRAACSEHQKDLEVLQTELRALDSMGRRQAITQCPGDSEDHAGTSEKEGGPGQAGSPKSKSAAELQPSEGCSLREENSQLKEAVKRLQAEVEQHQQEALQLRDQSRLLEEDQQAQRAREVEILRQEHRKEMQAMVADFSSAQARLQARLAALETELKDSGEKPGKGASRPEDVQLIGRLQTRLKEREEIIKQLTEERRFHYAAFPSAMSHRNRSFSFNPHPGYLTPSMKKKKMEEVPSRVVSVPNLASYAKNFLSGDLSSRINAPPITKSPSLDPGPSCGRPYKPTPSLDVQTATRTQDDDTAQPKEAQQKQGSAHQEWFTKYFSF", "length": 1007, "header": "tr|A0A3Q1M052-1|G3MYE6_BOVIN Computationally mapped isoform of Family with sequence similarity 184 member B OS=Bos taurus OX=9913 GN=FAM184B PE=4 SV=2 CANONICAL=G3MYE6-1" }, "locus": { "chromosome": "6", "start_pos": 37238319, "end_pos": 37181078, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000083103.2", "url": "https://www.ensembl.org/id/ENSBTAT00000083103.2" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000066570.2", "url": "https://www.ensembl.org/id/ENSBTAP00000066570.2" } ] } }, { "isoform_ac": "G3MYE6-1", "url": "https://www.uniprot.org/uniprotkb/G3MYE6/entry", "sequence": { "sequence": "MASALNSKIHAPGNCPASKADARGGAGWRMDCDPEMHMKMCKKIAQLTKVIYALNTRQDETEAGMEALREAHQEELQQAVAETEARLLQAQGRVGEEEALRQRIQALESALELQKQLTQEALAQSASCRLETQERELRVEAEHAERVLTLSKEMLELKADYEKRLRHLSGHEAPRWDRLTKEGPEPKAEPGCGPEMREVLLEVERLRTENQQLSKDYARKAEELQATYERENEAVRQAMQQSVSEALWQWQEKETDLRKNFQAQEAALQAQVRKLEGDLEHRGRKISDLKKYAQKLKDRIQDLDVQLKEARQENSELKSTAKKLGEKLAIAKDKLMLQECHVTQKTGDMKTERVSENKVLRKENNLEACSLHPQQDQNFAKECPCTKGGTDTQTKKEACIETEYMKQKYEEDLRKIKHQTEEEKKHLKDQLMKRLEDLVKKHTVEIKSVRSSVEAERKRLQKEVEAQLEEVKKKSENEIKQLEEEKAALSVKLQNSLLEVLRLEEFIQQNKACPPRGDEKPQELDYQHCNILETQDPCLRPNEPSQTLPRGEEYQDKLAAEEGTSSDEEERIEAPIKEGGDLQPPLGSLPKEKAPEIQRLQEEWQSQKARLQAQVSQMQQALEQCATNYREDLRELKQLSDHEREQLRHELQETIQQNQAAKAQLEAAHKRALCMLEKAKNQEVKATEERLKKESSHSLQIQHQAHRLEMQALEEKARQELQGELERMQAQQALLLESLRQELAEQRAACSEHQKDLEVLQTELRALDSMGRRQAITQCPGDSEDHAGTSEKEGGPGQAGSPKSKSAAELQPSEGCSLREENSQLKEAVKRLQAEVEQHQQEALQLRDQSRLLEEDQQAQRAREVEILRQEHRKEMQAMVADFSSAQARLQARLAALETELKDSGEKPGKGASRPEDVQLIGRLQTRLKEREEIIKQLTEERRFHYAAFPSAMSHRNRSFSFNPHPGYLTPSMKKKKMEEVPSRVVSVPNLASYAKNFLSGDLSSRINAPPITKSPSLDPGPSCGRPYKPTPSLDVQTATRTQDDDTAQPKEAQQKQGSAHQEWFTKYFSF", "length": 1071, "header": "tr|G3MYE6-1|G3MYE6_BOVIN Isoform 1 of Family with sequence similarity 184 member B OS=Bos taurus OX=9913 GN=FAM184B PE=4 SV=3 CANONICAL=G3MYE6-1" }, "locus": { "chromosome": "6", "start_pos": 37300921, "end_pos": 37181078, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000064667.3", "url": "https://www.ensembl.org/id/ENSBTAT00000064667.3" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000054578.3", "url": "https://www.ensembl.org/id/ENSBTAP00000054578.3" } ] } } ], "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "other", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 1031, "start_aa": "Thr", "end_pos": 1031, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr1031", "evidence": [ { "id": "", "database": "GlyGen", "url": "https://data.glygen.org/" } ], "filter_code": "000000000000000010000.00000000001000.0.01000" } ], "phosphorylation": [], "glycation": [], "keywords": [ "glycoprotein", "glycoprotein_predicted" ], "publication": [], "pathway": [ { "id": "bta:523874", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?bta:523874", "resource": "KEGG Pathway" } ], "orthologs": [ { "uniprot_canonical_ac": "A0AC58J492-1", "protein_name": "Protein FAM184B isoform X1", "gene_name": "fam184b", "tax_id": 7955, "organism": "Danio rerio", "sequence": { "sequence": "MASSSGKMNHPPGGSGACNGTAIADIPSVNVEQELYDYQMHTKMCKKIAQLTKVIYSLNTKNEEQEATLQSLRRVATETQGSLQPTTGQDEEEEESASILRTRLLELQATVEEVEERGQRAEIEYAERIAVLTQETSDLRRDYQNLQTDRDNQHKLLQQTQDEKKHLENECQELRRARDEERKREEEEKMQRVEEERKKEMEEKNRETEERNRVSQERKRVEEECEVKLKTARKEVQVLREEKESMEKQLKSDMEEWKKRVKEMEDERKDEQEAAKKALQQSLNEHINQWHQREQENRKSQNSTLQQRLRKAEADLEVREQRLNESNRHCSKLQERVEDLEEQLEDGRHRVAEAESVAKKAEEELAVAKERLLLQENELQSKSDELMSQSSSQVRFSAEVEDLRSQLSRLNIRNKELELQNSGRSNDHARMLKQHADTLSSMRLELQRAHTEEIRRLQQEVENERKNDRQELEEEKKQVQQKMEEEKVRLKEQLRKALEEVIRKHASELRHAHTMLDAEKKKTQQAEEQMKSTEEDRKLLETEREELCNQLQLSKTEMTKLEEMIQTLEREREEEKERAKKREKECAEVEQQSACGLECVRMREELENTHSSMQQIQEEFTAQKEVLQAEISALQQERDILQQSNHGLEERIRLQFEKQFSDQIVELKREKEEEIRKMNQQWQHRVEELQTQLEERRVLSEKMEGERERRYGNGEMERMKQEIQKTREMNSSLRAQLHSTIQEKERMMRQQLQVVKEEDEDEEDGKSTREREEERDKRGWREREEELLRVERLNHQRALQVLETQANEELQAERQRLLTQHKLQLDKQKAELTQQHTEWVRQVTQRHMQQIEDLQNEIHTHTQMMALQQDLKQQNRLQSLERQLDEKSSEVQELKRENEDLKERINALSSRREEQDDYKQKHKSFPEEKHEDGEADGSDHRNNMETVKKEHRMEIQTIISDFSTAQTRLQARIVALETELREREERGKRRVEDLHTIAKLQDKLSERDQLIKNLVEDLHQLSQHPPLCSDEILKPHESRTQAGTLTPNMKKKTVEDASIPNLCSYDGGSPKAKCSPVMERVLPSLEQSGRGTPLTRTHTPTSPHAEHRASVRHSRPSSQELRHQPQLKINYNQHIRTPAEQRVIETGPDGQDPQKQEWFTKYFSF", "length": 1165 }, "evidence": [ { "id": "G3MYE6", "url": "https://omabrowser.org/oma/group/G3MYE6/", "database": "OMA" } ], "glygen_name": "Zebrafish", "common_name": "Zebrafish" }, { "uniprot_canonical_ac": "D3ZTZ0-1", "protein_name": "Family with sequence similarity 184, member B", "gene_name": "Fam184b", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MASALNSKIHPPGTCAGSKADARGGSGWRMDCDPEMHVKMCKKIAQLTKVIYALNTRQDEVETSTESLREAHQEELQDTVAETRTRLLQEQAQARTSEDAEALLKRIQTLENALELQKRLTQEALAESASCKLETKERELRVEAEHAERVLILSKEMLELKADYEKRLQLLTNHEGPQWGQLSQESPDATAESGQRPEMHQVLLEVERLRAENKQLSQDYARKAEELQATYERENEAIRQAMQQSVSEALWQWQEKESGLRKNFQVQESALQAQVRKLEGDLEHRGRKISDLKKYAQKLKERIQDLDVQLREARQENSELKNTARKLGEKLVIAKDRLMLQEGHVTQKTDDVKTEDRVLGKRDDPEACTLHPPQEQGFPKLCHCRKGGSETQNKKEEASGGIEHMRQQYEEDLRKVRHQTEEEKQQLREQLGKRLEDLVKKHTMEMKSVRSSVEVERKKLKEVEAQLEEVKTKSEREIKQLEDEKAALSAKLQNSLLENPCSRPKKPSQTPPREESPEKLTDGEETSSDEEERTGETLKEGSNLPPPLESVMKEKAIEIGRRPEDWQSQKTKLQTQAAEECLTKEAPDSLQAHLLELRALEEKAREELQEACEQMQAGQPGLLESLRQELTGQRVACCEHQKALEELQNELRAMGPLGKPQAINRCSGDSRDHTFITEDVGITGLPGSLPCAAEKGLLEENAQLQDTVLRLRAEVDQHLQEALQLREQHRLLEDQKAQRAMEVEALRQEHRKEMQAMVADFSGAQARLQARMAALEAELKDSGEKAGKGTSRPEDLQLIGRLQTRLKEREDIIRQLTEERRFHYAAFPSAVSHRNRSFSFNPHPGYLTPSMKKKKMEEVPSRVVSVPNLASYAKNFLSGDLSSRINAPPITKSPSLDPSPSCGQPYKPTQLLDGKTATRAQDEEPAQPKEATQKQGSPHQEWFTKYFSF", "length": 949 }, "evidence": [ { "id": "G3MYE6", "url": "https://omabrowser.org/oma/group/G3MYE6/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "I3LV88-1", "protein_name": "Family with sequence similarity 184 member B", "gene_name": "FAM184B", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MASALNSKIHAPGTCPGSKADACSGAGWRMDCDPEMHVKMCKKIAQLTKVIYALNTRQDEAEASMEALREAHQEELRSAVAETQARLLQEQGRAGEEALRQRIQALESALELQKRMTQEALAQSATCRLETKERELRVEAEHAERVLTLSKEMLELKADYEKRLRHLSGQEAPRWSPEPKAEPGSGGGGLEMREVLLEVERLRAENQQLSKDYARKAEELQATYERENEAIRQAMQQSVSEALWQWQEKETDLRKNFQVQESALQAQVRKLEGDLEHRGRRISDLKKYAQKLKDRIQDLDVQLKEARQENSELKSTAKKLGEKLAVAKDRLMLQECHMTQKTDDMKMERVPENEVLEKENDLESHRGYPQQDQNFLKECPCTKGGPDTQTKKEASIETEHMKQQYEEDLRKIKHQTEEEKKHLKEQLVKRLEDLVKKHSVEIRSVCATVEAERKRLQKEVEAQLEEVKKKSESEIKHLEEEKTALSVKLQNSLLEVLRLEEFIQQNKVHPPRGDERPQELDHQQCSIFETQDPCLKSNEPSQTLPRGEEYPDKVAAGEGTSSDKEERIEVPLKEGVDLQPPLGPLPKEKTLDLERLQEEWQSQKARLQAQVLQMQQALEQCASSYREDLRELKQLSDQEREQLQRELQETVQQNQAARAQLEASHQRALRVLEKAKNQELKATEERLKKESSHSLQIQHQAHRLELQALEEKARQELQGALERMQAQQALLLESLRQELSEQRAACSEHQKDLEMLQAERRAPGSMGRWQAITQDPGDSEGHTTGEEGGCPGQEAPPKGKGAVEQEPGDGCGLWEENSQLKEAVQRLQAEVEQHQQEALQLRDQRRLLEEDQQAQRARELELLRQEHRKEMQAMVADFSSAQARLQARLAALETELKDSGEKPGKGASRPEDVQLIGRLQTRLKEREEIIKQLTEERRFHYAAFPGAMSHRNRSFSFNPHPGYLTPSMKKKKMEEVPSRVVSVPNLASYAKNFLSGDLSSRISAPPITKSPSLDPGPSCGRPYKPTPSLDAKTATRAQDDETAQSKEVQQKQGSAHQEWFTKYFSF", "length": 1066 }, "evidence": [ { "id": "G3MYE6", "url": "https://omabrowser.org/oma/group/G3MYE6/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "Q0KK56-1", "protein_name": "Protein FAM184B", "gene_name": "Fam184b", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MASALNSKIHPPGTCASSKADARGGSGWRMDCDPEMHVKMCKKIAQLTKVIYALNTRQDEVEVSVESIREAHQEDLQDTGAETRTRLPQEQSRTSEDAETLLKRIQTLENALELQKRLTQEALAESASCKLETKERELRVEAEHAERVLILSKEMLELKADYEKRLQLLTSHEGPQWGQLSQESPDATAESSQRPEMHQVLLEVERLRAENKQLSQDYARKAEELQATYERENEAIRQAMQQSVSEALWQWQEKESGLRKNFQVQESALQAQVRKLEGDLEHRGRKISDLKKYAQKLKERIQDLDVQLREARQENSELKSTARKLGEKLAIAKDRLMLQECHVTQKTDDMKTEDGVLGKRDDLEACSLHPQQEQGFPKLCHCRNGGSETQTKKEASGEMENMKQQYEEDLRKVRHQTEEEKQQLREQLGKRLEDLVKKHTMEMKSVCSTVEVERKKLKEVEAQLEEVKTKSEREIQQLQEEKAALSTKLQNSLLEDPCSRPKKPARDEGLEKLTDEEESSSDEEERTGESVKGKSDLQPPFESVMKEKAVEIGHRPEDWQSQRTKLQTQAAECLNKDSTDSLQAHLLELQALEDNARQELQEDCEQMQVQQSGLLESLRQELTEQRVACCEHQKALEMLQNEFRAVGPLGKWQATNQCPGDRRDHTFITEDMGVTGPPGSLPCAAEKGLLEENAQLQDTVLRLRAEVDQHLQEALQLREQHRLLEEDQKAQRAMEVEALRQEHRKEMQAMVADFSGAQARLQARLAALETELKESGEKAGKGTSRPEDLQLIGRLQTRLKEREDIIRQLTEERRFHYAAFPSAVSHRNRSFSFNPHPGYLTPSMKKKKMEEVPSRVVSVPNLASYAKNFLSGDLSSRINAPPITKSPSLDPSPSCSQPYKPTQLLDGKTASRTQDGEPAQPKEAPQKQGSPHQEWFTKYFSF", "length": 942 }, "evidence": [ { "id": "G3MYE6", "url": "https://omabrowser.org/oma/group/G3MYE6/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q9ULE4-1", "protein_name": "Protein FAM184B", "gene_name": "FAM184B", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MASALNSKINPPGTCQGSKADGGAGWRMDCDPQMHVKMCKKIAQLTKVIYALNTRQDEAEASMEALREAHQEELQNAVAETKARLLQEQGCAEEEALLQRIQALESALELQKRLTEEALAESASCRLETKERELRVEAEHAERVLTLSREMLELKADYERRLQHLTSHEATPQGRLPQESPETKSEPGQGPEMQEVLLEVQRLRVENQQLSKDYARKAEELQATYERENEAIRQAMQQSVSQALWQWQEKESDLRKNFQVQESALQAQVRKLEGDLEHRGRKISDLKKYAQKLKERIQDLDVQLKEARQENSELKGTAKKLGEKLAVAKDRMMLQECRGTQQTDAMKTELVSENKVLREENDLEAGNLHPQQDQSCLKECPCMKGGTDMQTKKEASAETEYMKQQYEEDLRKIKHQTEEEKKHLKDQLVKRLEDLVKKHTVEIKSVRSSVEAERKKLQREVEAQLEEVRKKSEKEIKQLEEEKAALNVKLQNSLLEVLRLEEFIQQNKTRPTGAEESPQELGRQHCSILETQDPCLKLDETSPRGEEYQDKLAAEEGTSSDEEERTKVLLKEGSDPQPPLGSLLKEKTSKIQRLEEDWQSQKAKLQAQVSQMQQALEQCTSNYREDLQALKQLSDLEREKLQRELQETTQQNHAMKAQLEASHQRALRMLEKARHQELKATEERLKKESSHSLQIQHQTHRLELQALEEKARQELQEERERMQAQQALLLESLRQELSEQQAACSGHQKDLEALQAELRALGRQQASSQCPGDSKDHIIATEERGGPGQAGSPPGAAGQGSGEGCGLWEENAQLQDAVRRLRAEVEQHQQEAQKLRDQRRFLEETQQAQRAREVETLRQEHRKEMQAMVADFSSAQAQLQARLAALEAELKDSGEKPGKGASRPEDLQLIGRLQTRLKEREDIIKQLTEERRFHYAAFPSAMSHRNRSFSFNPHPGYLTPSMKKKKVEDVPSRVVSVPNLASYAKNFLSGDLSSRINAPPITTSPSLDPSPSCGRTYKPNQSTDAKTATRTPDGETAQAKEVQQKQGSPHQEWFTKYFSF", "length": 1060 }, "evidence": [ { "id": "G3MYE6", "url": "https://omabrowser.org/oma/group/G3MYE6/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" } ], "go_annotation": {}, "pro_annotation": [], "site_annotation": [ { "start_pos": 957, "end_pos": 959, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [ { "pdb_id": "AF-G3MYE6-F1", "pdb_chain": "global", "start_pos": 1, "end_pos": 1071, "overlap": "1.0", "method": "AlphaFold", "type": "alphafold", "resolution": -1.0, "url": "https://data.glygen.org/ln2downloads/pdb/current/AF-G3MYE6-F1.pdb", "url_external": "https://alphafold.ebi.ac.uk/entry/G3MYE6" } ], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "G3MYE6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3MYE6" }, { "id": "PF15665", "database": "Pfam", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF15665" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "Protein FAM184A/B N-terminal", "eco_id": "ECO_0000259", "start_pos": 50, "end_pos": 256, "start_aa": "Val", "end_aa": "Asp", "glycosite_overlap": [] } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" }, { "name": "homologset.oma", "label": "OMA Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [ 1031 ], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 957, "end_pos": 959 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 1 }, { "field": "total_sites", "count": 1 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 1 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "exact_sites", "count": 1 }, { "field": "exact_o_linked_sites", "count": 1 }, { "field": "fuzzy_sites", "count": 0 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_pos", "start_aa", "end_pos", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 1 }, { "field": "total_sites", "count": 1 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 1 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "exact_sites", "count": 1 }, { "field": "exact_o_linked_sites", "count": 1 }, { "field": "fuzzy_sites", "count": 0 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_pos", "start_aa", "end_pos", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ], "tool_support": { "graph_view": "yes" } }, { "uniprot_canonical_ac": "F6RZ71-1", "uniprot_ac": "F6RZ71", "uniprot_id": "F6RZ71_BOVIN", "mass": { "chemical_mass": 16319.0, "monoisotopic_mass": 16319.0 }, "refseq": { "ac": "XP_010799224", "name": "MAP3K7 C-terminal-like protein isoform X1", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_010799224" }, "gene_names": [ { "name": "MAP3K7CL", "type": "recommended", "evidence": [ { "id": "F6RZ71", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F6RZ71" } ] }, { "name": "MAP3K7CL", "type": "synonym", "evidence": [ { "id": "XP_010799224", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_010799224" } ] } ], "protein_names": [ { "name": "MAP3K7 C-terminal like", "type": "synonym", "evidence": [ { "id": "F6RZ71", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F6RZ71/entry#names_and_taxonomy" } ] }, { "name": "MAP3K7 C-terminal-like protein isoform X1", "type": "synonym", "evidence": [ { "id": "XP_010799224", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_010799224" } ] } ], "function": [], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Bos taurus", "taxid": 9913, "evidence": [ { "database": "UniProtKB", "id": "F6RZ71", "url": "https://www.uniprot.org/uniprotkb/F6RZ71" } ], "common_name": "Bovine", "glygen_name": "Bovine", "reference_species": "Bos taurus [9913]" } ], "gene": [ { "name": "MAP3K7CL", "url": "https://www.uniprot.org/uniprotkb/F6RZ71", "locus": { "chromosome": "1", "start_pos": 7005503, "end_pos": 7053301, "strand": "+", "evidence": [ { "database": "Ensembl Gene", "id": "ENSBTAG00000007444", "url": "https://www.ensembl.org/id/ENSBTAG00000007444" } ] } } ], "crossref": [ { "id": "F6RZ71", "url": "https://alphafold.ebi.ac.uk/entry/F6RZ71", "database": "AlphaFoldDB", "categories": [] }, { "id": "ENSBTAG00000007444", "url": "https://bgee.org/?page=gene&gene_id=ENSBTAG00000007444", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "540879", "url": "https://www.ncbi.nlm.nih.gov/gene/540879", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR042800", "url": "https://www.ebi.ac.uk/interpro/entry/IPR042800", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "bta:540879", "url": "https://www.genome.jp/dbget-bin/www_bget?bta:540879", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "MAREFHH", "url": "https://omabrowser.org/oma/group/MAREFHH/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "A0A3Q1M0Z3", "url": "https://www.orthodb.org/?gene=A0A3Q1M0Z3", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "F6RZ71", "url": "https://www.orthodb.org/?gene=F6RZ71", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR47140", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR47140", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR47140:SF1", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR47140:SF1", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF27575", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF27575", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "XP_010799224", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_010799224", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A3Q1M0Z3", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1M0Z3", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A3Q1M0Z3-1", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1M0Z3-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "F6RZ71", "url": "https://www.uniprot.org/uniprotkb/F6RZ71", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "F6RZ71-1", "url": "https://www.uniprot.org/uniprotkb/F6RZ71-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MISTARVPADKPVRIAFSLDNAADDTPPEDAIPLVFPELEQQLQPLPPCHDSMESMQVYKQHCQIAEEYREVKKEIALLEERKKELIAKLDQAEKEKLDAAQLAREFEALTEENRTLKLAQSQCVEQLEKLRIQYQKRQGSS", "length": 142, "header": "tr|F6RZ71-1|F6RZ71_BOVIN Isoform 1 of MAP3K7 C-terminal like OS=Bos taurus OX=9913 GN=MAP3K7CL PE=4 SV=1 CANONICAL=F6RZ71-1" }, "isoforms": [ { "isoform_ac": "A0A3Q1M0Z3-1", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1M0Z3/entry", "sequence": { "sequence": "MVDSNQTRLHTNLEDPEEGQGSGAHMISTARVPADKPVRIAFSLDNAADDTPPEDAIPLVFPELEQQLQPLPPCHDSMESMQVYKQHCQIAEEYREVKKEIALLEERKKELIAKLDQAEKEKLDAAQLAREFEALTEENRTLKLAQSQCVEQLEKLRIQYQKRQGSS", "length": 167, "header": "tr|A0A3Q1M0Z3-1|F6RZ71_BOVIN Computationally mapped isoform of MAP3K7 C-terminal like OS=Bos taurus OX=9913 GN=MAP3K7CL PE=4 SV=1 CANONICAL=F6RZ71-1" }, "locus": { "chromosome": "1", "start_pos": 7052687, "end_pos": 7006445, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000071361.2", "url": "https://www.ensembl.org/id/ENSBTAT00000071361.2" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000063343.1", "url": "https://www.ensembl.org/id/ENSBTAP00000063343.1" } ] } }, { "isoform_ac": "F6RZ71-1", "url": "https://www.uniprot.org/uniprotkb/F6RZ71/entry", "sequence": { "sequence": "MISTARVPADKPVRIAFSLDNAADDTPPEDAIPLVFPELEQQLQPLPPCHDSMESMQVYKQHCQIAEEYREVKKEIALLEERKKELIAKLDQAEKEKLDAAQLAREFEALTEENRTLKLAQSQCVEQLEKLRIQYQKRQGSS", "length": 142, "header": "tr|F6RZ71-1|F6RZ71_BOVIN Isoform 1 of MAP3K7 C-terminal like OS=Bos taurus OX=9913 GN=MAP3K7CL PE=4 SV=1 CANONICAL=F6RZ71-1" }, "locus": { "chromosome": "1", "start_pos": 7051154, "end_pos": 7006445, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000049195.3", "url": "https://www.ensembl.org/id/ENSBTAT00000049195.3" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000046126.2", "url": "https://www.ensembl.org/id/ENSBTAP00000046126.2" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [ { "id": "bta:540879", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?bta:540879", "resource": "KEGG Pathway" } ], "orthologs": [ { "uniprot_canonical_ac": "A0A8V0YA83-1", "protein_name": "MAP3K7 C-terminal like", "gene_name": "MAP3K7CL", "tax_id": 9031, "organism": "Gallus gallus", "sequence": { "sequence": "MKKCTGLKVSWLYPWDHADLSHHQLEQTSKSIGSSAHMITTARVPADKPVRIAFSLDESPDDDAPENSFPLAFPELDQQLQPLPPCHDSQESMQVYKQHCKIAEEYHEVKKEIALLEERKKELIARLEQVEKESMDAAQLAKEYAELTEENRTLKLAQTQCVEQLEKLRIQYQKRQGSS", "length": 179 }, "evidence": [ { "id": "F6RZ71", "url": "https://omabrowser.org/oma/group/F6RZ71/", "database": "OMA" } ], "glygen_name": "Chicken", "common_name": "Chicken" }, { "uniprot_canonical_ac": "A0ABK0LTI0-1", "protein_name": "MAP3K7 C-terminal like", "gene_name": "Map3k7cl", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MELRSNPRSLEVQISSLCLVTSLKSTRKPLPGFTTLHSSRLPRKGLYATGRPQDMQVHDPRNDTPSEEATPLVFPELEQQLQPLPPCHDSAESMQVFKQHCQIAEEYHEVKKEIALLEERKKELIAKLDQAEKEKLDAAQLVREFEALTEENRTLKMAQSQCVEQLEKLRIQYQKRQGSS", "length": 180 }, "evidence": [ { "id": "F6RZ71", "url": "https://omabrowser.org/oma/group/F6RZ71/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "G3GT08-1", "protein_name": "MAP3K7 C-terminal-like protein isoform X4", "gene_name": "Map3k7cl", "tax_id": 10029, "organism": "Cricetulus griseus", "sequence": { "sequence": "MISTARVPADKPVRIAFSLNDAPDDTPSEDAVPLVFPELEQQLQPLPPCHDSVESMQVFKQHCQIAEEYHEVKKEIALLEERKKELIAKLDQAEKEKRDAAQLVREFEALTEENRTLKMAQSQCVQQLEKLRIQYQKRQGSS", "length": 142 }, "evidence": [ { "id": "F6RZ71", "url": "https://omabrowser.org/oma/group/F6RZ71/", "database": "OMA" } ], "glygen_name": "Hamster", "common_name": "Chinese hamster" }, { "uniprot_canonical_ac": "P57077-4", "protein_name": "MAP3K7 C-terminal-like protein", "gene_name": "MAP3K7CL", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MISTARVPADKPVRIAFSLNDASDDTPPEDSIPLVFPELDQQLQPLPPCHDSEESMEVFKQHCQIAEEYHEVKKEITLLEQRKKELIAKLDQAEKEKVDAAELVREFEALTEENRTLRLAQSQCVEQLEKLRIQYQKRQGSS", "length": 142 }, "evidence": [ { "id": "F6RZ71", "url": "https://omabrowser.org/oma/group/F6RZ71/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "P58500-1", "protein_name": "MAP3K7 C-terminal-like protein", "gene_name": "Map3k7cl", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MISTARVPADKPVRIAFSLNDAPDDTPSEDAIPLVFPELEQQLQPLPPCHDSVESMQVFKQHCQIAEEYHEVKKEIALLEERKKELIAKLDQAEKEKLDAAQLVQEFEALTEENRTLKMAQSQCVEQLENLRIQYQKRQGSS", "length": 142 }, "evidence": [ { "id": "F6RZ71", "url": "https://omabrowser.org/oma/group/F6RZ71/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" } ], "go_annotation": {}, "pro_annotation": [], "site_annotation": [ { "start_pos": 114, "end_pos": 116, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [ { "pdb_id": "AF-F6RZ71-F1", "pdb_chain": "global", "start_pos": 1, "end_pos": 142, "overlap": "1.0", "method": "AlphaFold", "type": "alphafold", "resolution": -1.0, "url": "https://data.glygen.org/ln2downloads/pdb/current/AF-F6RZ71-F1.pdb", "url_external": "https://alphafold.ebi.ac.uk/entry/F6RZ71" } ], "lectin_list": [], "domain_list": [], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" }, { "name": "homologset.oma", "label": "OMA Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 114, "end_pos": 116 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ], "tool_support": { "graph_view": "yes" } }, { "uniprot_canonical_ac": "G3MXX4-1", "uniprot_ac": "G3MXX4", "uniprot_id": "G3MXX4_BOVIN", "mass": { "chemical_mass": 52143.0, "monoisotopic_mass": 52143.0 }, "refseq": { "ac": "XP_024839794", "name": "sodium-dependent phosphate transport protein 1 isoform X1", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_024839794" }, "gene_names": [ { "name": "SLC17A1", "type": "recommended", "evidence": [ { "id": "G3MXX4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3MXX4" } ] }, { "name": "SLC17A1", "type": "synonym", "evidence": [ { "id": "XP_024839794", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_024839794" } ] } ], "protein_names": [ { "name": "Solute carrier family 17 member 1", "type": "synonym", "evidence": [ { "id": "G3MXX4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3MXX4/entry#names_and_taxonomy" } ] }, { "name": "sodium-dependent phosphate transport protein 1 isoform X1", "type": "synonym", "evidence": [ { "id": "XP_024839794", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_024839794" } ] } ], "function": [], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Bos taurus", "taxid": 9913, "evidence": [ { "database": "UniProtKB", "id": "G3MXX4", "url": "https://www.uniprot.org/uniprotkb/G3MXX4" } ], "common_name": "Bovine", "glygen_name": "Bovine", "reference_species": "Bos taurus [9913]" } ], "gene": [ { "name": "SLC17A1", "url": "https://www.uniprot.org/uniprotkb/G3MXX4", "locus": { "chromosome": "23", "start_pos": 32068361, "end_pos": 32022561, "strand": "-", "evidence": [ { "database": "Ensembl Gene", "id": "ENSBTAG00000037917", "url": "https://www.ensembl.org/id/ENSBTAG00000037917" } ] } } ], "crossref": [ { "id": "G3MXX4", "url": "https://alphafold.ebi.ac.uk/entry/G3MXX4", "database": "AlphaFoldDB", "categories": [] }, { "id": "ENSBTAG00000037917", "url": "https://bgee.org/?page=gene&gene_id=ENSBTAG00000037917", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "507535", "url": "https://www.ncbi.nlm.nih.gov/gene/507535", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR011701", "url": "https://www.ebi.ac.uk/interpro/entry/IPR011701", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR020846", "url": "https://www.ebi.ac.uk/interpro/entry/IPR020846", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR036259", "url": "https://www.ebi.ac.uk/interpro/entry/IPR036259", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR050382", "url": "https://www.ebi.ac.uk/interpro/entry/IPR050382", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "bta:507535", "url": "https://www.genome.jp/dbget-bin/www_bget?bta:507535", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "A0A3Q1M176", "url": "https://www.orthodb.org/?gene=A0A3Q1M176", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "F1N6Z8", "url": "https://www.orthodb.org/?gene=F1N6Z8", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "G3MXX4", "url": "https://www.orthodb.org/?gene=G3MXX4", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR11662", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR11662", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR11662:SF26", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR11662:SF26", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF07690", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF07690", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "R-BTA-427652", "url": "https://www.reactome.org/PathwayBrowser/#R-BTA-427652", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "XP_024839794", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_024839794", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "71255", "url": "https://www.rhea-db.org/rhea/71255", "database": "Rhea", "categories": [ "Enzyme and Pathway" ] }, { "id": "A0A3Q1M176", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1M176", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A3Q1M176-1", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1M176-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0AAA9RYV0", "url": "https://www.uniprot.org/uniprotkb/A0AAA9RYV0", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0AAA9RYV0-1", "url": "https://www.uniprot.org/uniprotkb/A0AAA9RYV0-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0AAA9T2P7", "url": "https://www.uniprot.org/uniprotkb/A0AAA9T2P7", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0AAA9T2P7-1", "url": "https://www.uniprot.org/uniprotkb/A0AAA9T2P7-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0AAA9U097", "url": "https://www.uniprot.org/uniprotkb/A0AAA9U097", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0AAA9U097-1", "url": "https://www.uniprot.org/uniprotkb/A0AAA9U097-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "F1N6Z8", "url": "https://www.uniprot.org/uniprotkb/F1N6Z8", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "F1N6Z8-1", "url": "https://www.uniprot.org/uniprotkb/F1N6Z8-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "G3MXX4", "url": "https://www.uniprot.org/uniprotkb/G3MXX4", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "G3MXX4-1", "url": "https://www.uniprot.org/uniprotkb/G3MXX4-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MQVDNQVSPGKVPYFCSVRYGIAVFLLLCNVIIMSQRVCLSLTMIAMVNSTEPHGLSNTSTKELQDNIKNPVYNWSTEIQGIMLSSIFYGVLISQIPAGYLSGIYSLKKMIGFALLLSSLFTLLLPLAAEFGEILVIICRVIKGLFQGITLTTQQVIWIKWAPPLELGRLTALSLSGLLLGPCIVLLITGFICDSLGWPMVFYIFGACGCALSVLWFILFYEDPKDHPFISNREKEYITSALTQQVSSSTLIKVPIKAMLKSTPLWVISLCNFAFFWSNTFLSIYIPIYIDYKLHVDVEENGLLSSLPHLFAWIFAVLAGYMADIFQTRNTFSLVTIRKLFTSLGLLLPSLFSLCLLYLSSSYYATIIFLILANSTGSFAMGGIIINVLDIAPRYYGFLRGITNVIGLTGGLIASTVTGIILSEDAESPWLKIFLLMIANNMISLIFYLIFAKAEVQEWAKERQNTYL", "length": 468, "header": "tr|G3MXX4-1|G3MXX4_BOVIN Isoform 1 of Solute carrier family 17 member 1 OS=Bos taurus OX=9913 GN=SLC17A1 PE=3 SV=3 CANONICAL=G3MXX4-1" }, "isoforms": [ { "isoform_ac": "A0A3Q1M176-1", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1M176/entry", "sequence": { "sequence": "MGIENKLFSKKKNNHNTIMQVDNQVSPGKVPYFCSVRYGIAVFLLLCNVIIMSQRVCLSLTMIAMVNSTEPHGLSNTSTKELQDNIKNPVYNWSTEIQGIMLSSIFYGVLISQIPAGYLSGIYSLKKMIGFALLLSSLFTLLLPLAAEFGEILVIICRVIKGLFQGITLTTQQVIWIKWAPPLELGRLTALSLSGLLLGPCIVLLITGFICDSLGWPMVFYIFGACGCALSVLWFILFYEDPKDHPFISNREKEYITSALTQQVSSSTLIKVPIKAMLKSTPLWVISLCNFAFFWSNTFLSIYIPIYIDYKLHVDVEENGLLSSLPHLFAWIFAVLAGYMADIFQTRNTFSLVTIRKLFTSLGLLLPSLFSLCLLYLSSSYYATIIFLILANSTGSFAMGGIIINVLDIAPRYYGFLRGITNVIGLTGGLIASTVTGIILSEDAESPWLKIFLLMIANNMISLIFYLIFAKAEVQEWAKERQNTYL", "length": 486, "header": "tr|A0A3Q1M176-1|G3MXX4_BOVIN Computationally mapped isoform of Solute carrier family 17 member 1 OS=Bos taurus OX=9913 GN=SLC17A1 PE=3 SV=2 CANONICAL=G3MXX4-1" }, "locus": { "chromosome": "23", "start_pos": 32068356, "end_pos": 32022732, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000074548.3", "url": "https://www.ensembl.org/id/ENSBTAT00000074548.3" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000067033.2", "url": "https://www.ensembl.org/id/ENSBTAP00000067033.2" } ] } }, { "isoform_ac": "A0AAA9RYV0-1", "url": "https://www.uniprot.org/uniprotkb/A0AAA9RYV0/entry", "sequence": { "sequence": "MREDGEYQLSLWDDCSCGQGIENKLFSKKKNNHNTIMQVDNQVSPGKVPYFCSVRYGIAVFLLLCNVIIMSQRVCLSLTMIAMVNSTEPHGLSNTSTKELQDNIKNPVYNWSTEIQGIMLSSIFYGVLISQIPAGYLSGIYSLKKMIGFALLLSSLFTLLLPLAAEFGEILVIICRVIKGLFQGITLTTQQVIWIKWAPPLELGRLTALSLSGLLLGPCIVLLITGFICDSLGWPMVFYIFGACGCALSVLWFILFYEDPKDHPFISNREKEYITSALTQQVSSSTLIKVPIKAMLKSTPLWVISLCNFAFFWSNTFLSIYIPIYIDYKLHVDVEENGLLSSLPHLFAWIFAVLAGYMADIFQTRNTFSLVTIRKLFTSLGLLLPSLFSLCLLYLSSSYYATIIFLILANSTGSFAMGGIIINVLDIAPRYYGFLRGITNVIGLTGGLIASTVTGIILSEDAESPWLKIFLLMIANNMISLIFYLIFAKAEVQEWAKERQNTYL", "length": 504, "header": "tr|A0AAA9RYV0-1|G3MXX4_BOVIN Computationally mapped isoform of Solute carrier family 17 member 1 OS=Bos taurus OX=9913 GN=SLC17A1 PE=3 SV=1 CANONICAL=G3MXX4-1" }, "locus": { "chromosome": "23", "start_pos": 32068356, "end_pos": 32027750, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000115986.2", "url": "https://www.ensembl.org/id/ENSBTAT00000115986.2" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000077796.1", "url": "https://www.ensembl.org/id/ENSBTAP00000077796.1" } ] } }, { "isoform_ac": "A0AAA9T2P7-1", "url": "https://www.uniprot.org/uniprotkb/A0AAA9T2P7/entry", "sequence": { "sequence": "MSLSSSLSSKSSKGIENKLFSKKKNNHNTIMQVDNQVSPGKVPYFCSVRYGIAVFLLLCNVIIMSQRVCLSLTMIAMVNSTEPHGLSNTSTKELQDNIKNPVYNWSTEIQGIMLSSIFYGVLISQIPAGYLSGIYSLKKMIGFALLLSSLFTLLLPLAAEFGEILVIICRVIKGLFQGITLTTQQVIWIKWAPPLELGRLTALSLSGLLLGPCIVLLITGFICDSLGWPMVFYIFGACGCALSVLWFILFYEDPKDHPFISNREKEYITSALTQQVSSSTLIKVPIKAMLKSTPLWVISLCNFAFFWSNTFLSIYIPIYIDYKLHVDVEENGLLSSLPHLFAWIFAVLAGYMADIFQTRNTFSLVTIRKLFTSLGLLLPSLFSLCLLYLSSSYYATIIFLILANSTGSFAMGGIIINVLDIAPRYYGFLRGITNVIGLTGGLIASTVTGIILSEDAESPWLKIFLLMIANNMISLIFYLIFAKAEVQEWAKERQNTYL", "length": 498, "header": "tr|A0AAA9T2P7-1|G3MXX4_BOVIN Computationally mapped isoform of Solute carrier family 17 member 1 OS=Bos taurus OX=9913 GN=SLC17A1 PE=3 SV=1 CANONICAL=G3MXX4-1" }, "locus": { "chromosome": "23", "start_pos": 32068356, "end_pos": 32031202, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000118507.2", "url": "https://www.ensembl.org/id/ENSBTAT00000118507.2" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000090910.1", "url": "https://www.ensembl.org/id/ENSBTAP00000090910.1" } ] } }, { "isoform_ac": "A0AAA9U097-1", "url": "https://www.uniprot.org/uniprotkb/A0AAA9U097/entry", "sequence": { "sequence": "MQVDNQVSPGKVPYFCSVRYGIAVFLLLCNVIIMSQRVCLSLTMIAMVNSTEPHGLSNTSTKELQDNIKNPVYNWSTEIQGIMLSSIFYGVLISQIPAGYLSGIYSLKKMIGFALLLSSLFTLLLPLAAEFGEILVIICRVIKGLFQGITLTTQQVIWIKWAPPLELGRLTALSLSGLLLGPCIVLLITGFICDSLGWPMVFYIFGACGCALSVLWFILFYEDPKDHPFISNREKEYITSALTQQNGLLSSLPHLFAWIFAVLAGYMADIFQTRNTFSLVTIRKLFTSLGLLLPSLFSLCLLYLSSSYYATIIFLILANSTGSFAMGGIIINVLDIAPRYYGFLRGITNVIGLTGGLIASTVTGIILSEDAESPWLKIFLLMIANNMISLIFYLIFAKAEVQEWAKERQNTYL", "length": 413, "header": "tr|A0AAA9U097-1|A0AAA9U097_BOVIN Computationally mapped isoform of Solute carrier family 17 member 1 OS=Bos taurus OX=9913 GN=SLC17A1 PE=3 SV=1 CANONICAL=G3MXX4-1" }, "locus": { "chromosome": "23", "start_pos": 32068356, "end_pos": 32033387, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000094405.2", "url": "https://www.ensembl.org/id/ENSBTAT00000094405.2" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000103315.1", "url": "https://www.ensembl.org/id/ENSBTAP00000103315.1" } ] } }, { "isoform_ac": "F1N6Z8-1", "url": "https://www.uniprot.org/uniprotkb/F1N6Z8/entry", "sequence": { "sequence": "MSLSSSLSSKSSKASLHRTKRNHFSVLNQGIENKLFSKKKNNHNTIMQVDNQVSPGKVPYFCSVRYGIAVFLLLCNVIIMSQRVCLSLTMIAMVNSTEPHGLSNTSTKELQDNIKNPVYNWSTEIQGIMLSSIFYGVLISQIPAGYLSGIYSLKKMIGFALLLSSLFTLLLPLAAEFGEILVIICRVIKGLFQGITLTTQQVIWIKWAPPLELGRLTALSLSGLLLGPCIVLLITGFICDSLGWPMVFYIFGACGCALSVLWFILFYEDPKDHPFISNREKEYITSALTQQVSSSTLIKVPIKAMLKSTPLWVISLCNFAFFWSNTFLSIYIPIYIDYKLHVDVEENGLLSSLPHLFAWIFAVLAGYMADIFQTRNTFSLVTIRKLFTSLGLLLPSLFSLCLLYLSSSYYATIIFLILANSTGSFAMGGIIINVLDIAPRYYGFLRGITNVIGLTGGLIASTVTGIILSEDAESPWLKIFLLMIANNMISLIFYLIFAKAEVQEWAKERQNTYL", "length": 514, "header": "tr|F1N6Z8-1|F1N6Z8_BOVIN Computationally mapped isoform of Solute carrier family 17 member 1 OS=Bos taurus OX=9913 GN=SLC17A1 PE=3 SV=4 CANONICAL=G3MXX4-1" }, "locus": { "chromosome": "23", "start_pos": 32068356, "end_pos": 32031202, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000008247.8", "url": "https://www.ensembl.org/id/ENSBTAT00000008247.8" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000008247.7", "url": "https://www.ensembl.org/id/ENSBTAP00000008247.7" } ] } }, { "isoform_ac": "G3MXX4-1", "url": "https://www.uniprot.org/uniprotkb/G3MXX4/entry", "sequence": { "sequence": "MQVDNQVSPGKVPYFCSVRYGIAVFLLLCNVIIMSQRVCLSLTMIAMVNSTEPHGLSNTSTKELQDNIKNPVYNWSTEIQGIMLSSIFYGVLISQIPAGYLSGIYSLKKMIGFALLLSSLFTLLLPLAAEFGEILVIICRVIKGLFQGITLTTQQVIWIKWAPPLELGRLTALSLSGLLLGPCIVLLITGFICDSLGWPMVFYIFGACGCALSVLWFILFYEDPKDHPFISNREKEYITSALTQQVSSSTLIKVPIKAMLKSTPLWVISLCNFAFFWSNTFLSIYIPIYIDYKLHVDVEENGLLSSLPHLFAWIFAVLAGYMADIFQTRNTFSLVTIRKLFTSLGLLLPSLFSLCLLYLSSSYYATIIFLILANSTGSFAMGGIIINVLDIAPRYYGFLRGITNVIGLTGGLIASTVTGIILSEDAESPWLKIFLLMIANNMISLIFYLIFAKAEVQEWAKERQNTYL", "length": 468, "header": "tr|G3MXX4-1|G3MXX4_BOVIN Isoform 1 of Solute carrier family 17 member 1 OS=Bos taurus OX=9913 GN=SLC17A1 PE=3 SV=3 CANONICAL=G3MXX4-1" }, "locus": { "chromosome": "23", "start_pos": 32068356, "end_pos": 32033387, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000064064.4", "url": "https://www.ensembl.org/id/ENSBTAT00000064064.4" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000054395.3", "url": "https://www.ensembl.org/id/ENSBTAP00000054395.3" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [ { "id": "bta:507535", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?bta:507535", "resource": "KEGG Pathway" }, { "id": "R-BTA-427652", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-BTA-427652", "resource": "Reactome", "description": "Sodium-coupled phosphate cotransporters" } ], "orthologs": [], "go_annotation": { "categories": [ { "name": "Molecular Function", "total": 2, "go_terms": [ { "name": "transmembrane transporter activity", "id": "GO:0022857", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0022857", "evidence": [ { "database": "UniProtKB", "id": "G3MXX4", "url": "https://www.uniprot.org/uniprotkb/G3MXX4" } ], "pmid": "" }, { "name": "symporter activity", "id": "GO:0015293", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0015293", "evidence": [ { "database": "UniProtKB", "id": "G3MXX4", "url": "https://www.uniprot.org/uniprotkb/G3MXX4" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 1, "go_terms": [ { "name": "apical plasma membrane", "id": "GO:0016324", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016324", "evidence": [ { "database": "UniProtKB", "id": "G3MXX4", "url": "https://www.uniprot.org/uniprotkb/G3MXX4" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 4, "go_terms": [ { "name": "sodium ion transport", "id": "GO:0006814", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006814", "evidence": [ { "database": "UniProtKB", "id": 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"RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_024831868" } ] }, { "name": "PRRC2C", "type": "synonym", "evidence": [ { "id": "XP_024831868", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_024831868" } ] } ], "protein_names": [ { "name": "Proline rich coiled-coil 2C", "type": "synonym", "evidence": [ { "id": "G3X6B2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3X6B2/entry#names_and_taxonomy" } ] }, { "name": "protein PRRC2C isoform X1", "type": "synonym", "evidence": [ { "id": "XP_024831868", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_024831868" } ] } ], "function": [], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Bos taurus", "taxid": 9913, "evidence": [ { "database": "UniProtKB", "id": "G3X6B2", "url": "https://www.uniprot.org/uniprotkb/G3X6B2" } ], "common_name": "Bovine", "glygen_name": "Bovine", "reference_species": "Bos taurus [9913]" } ], "gene": [ { "name": "PRRC2C", "url": "https://www.uniprot.org/uniprotkb/G3X6B2", "locus": { "chromosome": "16", "start_pos": 39080464, "end_pos": 38985099, "strand": "-", "evidence": [ { "database": "Ensembl Gene", "id": "ENSBTAG00000001821", "url": "https://www.ensembl.org/id/ENSBTAG00000001821" } ] } } ], "crossref": [ { "id": "ENSBTAG00000001821", "url": "https://bgee.org/?page=gene&gene_id=ENSBTAG00000001821", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "505359", "url": "https://www.ncbi.nlm.nih.gov/gene/505359", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR009738", "url": "https://www.ebi.ac.uk/interpro/entry/IPR009738", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR033184", "url": "https://www.ebi.ac.uk/interpro/entry/IPR033184", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "APIMQAP", "url": "https://omabrowser.org/oma/group/APIMQAP/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "A0A3Q1M475", "url": "https://www.orthodb.org/?gene=A0A3Q1M475", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "G3X6B2", "url": "https://www.orthodb.org/?gene=G3X6B2", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR14038", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR14038", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR14038:SF6", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR14038:SF6", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF07001", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF07001", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "XP_024831868", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_024831868", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A3Q1M475", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1M475", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A3Q1M475-1", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1M475-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A3Q1MUN8", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1MUN8", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A3Q1MUN8-1", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1MUN8-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0AAA9SCK8", "url": "https://www.uniprot.org/uniprotkb/A0AAA9SCK8", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0AAA9SCK8-1", "url": "https://www.uniprot.org/uniprotkb/A0AAA9SCK8-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0AAA9TMZ9", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TMZ9", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0AAA9TMZ9-1", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TMZ9-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "G3X6B2", "url": "https://www.uniprot.org/uniprotkb/G3X6B2", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "G3X6B2-1", "url": "https://www.uniprot.org/uniprotkb/G3X6B2-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "G3X6B3", "url": "https://www.uniprot.org/uniprotkb/G3X6B3", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "G3X6B3-1", "url": "https://www.uniprot.org/uniprotkb/G3X6B3-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MSEKSGQSTKAKDGKKYATLSLFNTYKGKSLETQKTTVAARHGLQSLGKVGISRRMPPPANLPSLKAENKGNDPNVNIVPKDGTGWASKQEQHEEEKAPEVPPAQPKPGVAAPPEVAPAPKSWASNKQGGQGDGIQVNSHFQQEFPSLQAAGDQEKKEKEANDDNYGPGPSLRPPNVACWRDGGKSASSSLTSDQDEKPGQDESTAGTSEQSDILKVVEKRIACGPPQAKLNGQQPALASQYRAMMPPYMFQQYPRMAYPPLHGPMRFPPSLSETNKGLRGRGPPPSWASEPERPSILSASELKELDKFDNLDAEADEGWAGAQMEVDYTEQLNFSDDDEQGSSSPKENSSEDQSSKASENTENRKEPDEVSNTKSSSQIPTQPSVAKGPYGKGPPFNQERGPSSHLPPPPKLLAQQHPPPDRQAVPGRPGPFPPKQQVPDEDEIWKQRRRQQSELSAAVERARKRREEEERRMEEQRKAACAEKLKRLDEKLGIVDKQPSPEEIREREREKEREKEWEREKELEKEQEREQEKEREKERERQQEKEKELEREQEKQREMEKERKQEKEKELERQQEKEKELQKTKEQEKECELEKRDREKVDEKTEHKEPTSEPMVEKPESENSCNKEDDPVFTRQDSNRSEKETTQVAHEPEPESGSQPRPAVLSGYFKQFQKSLPPRFQRQQEQMKQQQWQQQQQQGVLPQTVPSQPSGSAVPPPPHRPLYQPMQPHPQHLASMGFDPRWLMMQSYMDPRMISGRPAMDIPPIHPGMIPPKPLMRRDQMEGSPNNSESFEHLARSARDHAISLSEPRMMWGSDPYPHTEPQQATTPKAAEEPEDVRPEAPLDQEQITAAYPVEHGQLEVHPKPDFVRESSETDVQKFLSRSVEDIRPRHTDTNSQSTCFDVPDQKTITTPQEERISAGESQPARKRSVCHGSNHTQKSEELRNEPSANIPKVTSRGIDSKEPAERPEEKPKKEGFIRSSDGPKPEKLYKSKSETRWGPRPSSNRREEGNDRPVRRSGPIKKPILRDMKEEREQRKEKEGEKGEKVTEKVVKPEKTEKKEPLPPPPAPPAAPVQPQSVPPQPQPEPEKLPSVETSPSTLVQKPPQDTEKPLESVSSVEVEPAVKTVNQQAVTAPVVKEEKQPEKVISKDLVTERTRPDSRPTAKKESTLPPRTYWKEARDRDWFPDQGYRGRGRGEYYSRGRSYRGSYGGRGRGGRGHTRDYPQYRDSKPRAEHVAPGPLRQREESETRSESSDFEVVPKRRRQRGSETDTDSEIHESASDKDSLSKSKLPKREERPESKKPIKPQSSFKPENHVRIDNRPLEKSFVRDDDKSKPGFLPKGEPTRRGRGGTFRRGGRDPGGRPSRPSTLRRPAYRDNQWNPRQTEAPKPDSGEPPRRHEQFIPIPADKRPPKFERKFDPARERPRRQRPTRPPRQDKPPRFRRLREREAASKTNEVAVPTNGTVNNVVQEPVNSAGDISGNKTPDLSNQNSSDQANEEWETASESSDFNERRERDEKKNADLNAQVVVKTGENVVPPKREIAKRSFSSQRPGIDRQNRRGNNGPPKSGRNFSGPRNERRSGPPSKGGKRGPFDDQSAGTSGADPVNGSSAHHQEGAPNGTGQKNSKDSTGKKREDPKPGPKKPKEKVDALSQFDLNNYASVVIIDDHPEVTVVEDPQSNLNDDGFTEVVSKKQQKRLQDEERRKKEEQIIQVWNKKNANEKGRNQTSKLPPRFAKKQATGTQQVQPPASALTSAPGPGSTSAPVPATTPAPVPASTPAPLLASPVASVPAPTTVPVLTSTSAPLPALASASVPVPASTPTTAIASSPAPAPTPILASASSPASVPILTSASIPILASALAPASAPPPAISAAAVPASAPTAPTSAPASAPTPTLVQVPVPAPTAPGQTQGQTHKPVQSPLQTTTQSSKQPPPSIRLPSAQTPNGTDYVATGKPIQTSQSHGTLTAELWENKVAPPAVLNDISKKLGPISPPQPPSVSAWNKPLTSFGSATSSEGTKNSQESGVEIGIDTIQFGAPASNGNENEIVPVLSEKTTDKISEPKEQRQKQPRAGPIKAQKLPDLSPVENKEHKPGPIGKERSLKNRKVKDAQQVEPEGQEKPSPATVRSTDPVTTKETKAVSEMSTEIGTMISVSSTEYGTNVKESVTDYTTPSSSLPNTVATNNAKMEDTLVNNVPLPSTLPLPKRETIQQSSSLTSVPPTTFSLTFKMESARKAWENSPNVREKGSPVTSTAPPIASGVSSSASGPSTANYSSFSSASVPQIPVASVTPTTSLSGAGTYTTSSLSTKSTTTSDPPNICKVKPQQLQTSSLPSASHFSQLSCMPSLIAQQQQSPQVYVSQSAAAQIPAFYMDTSHLFNTQHARLAPPSLAQQQGFQPGLSQPTSVQQIPIPIYAPLQGQHQAQLSLGAGPAVSQAQELFSSSLQPYRSQPAFMQSSLSQPSMVLSGTAIHNFPAVQHQELAKAQSGLAFQQTSNTQPIPILYEHQLGQASGLGGSQLIDTHLLQARANLTQASNLYSGQVQQPGQTNFYNTAQSPSALQQVNYGMVTVPLPASQLSLPNFGSTGQPLIALPQTLQPPLQHTAPQAQAQSMSRTAQVSQPFRGLIPAGTQHSMIATTGKMSEMELKAFGSGIDIKPGTPPISGRSTTPTSSPFRATSTSPNSQSSKMNSIVYQKQFQSAPATVRMAQPFPTQFAPQILSQPNLVPPLVRAPHTNTFPAPVQRPPMALASQMPPPLTTGLMSHARLPHVARGPCGSLSGVRGNQAQAALKAEQDMKAKQRAEVLQSTQRFFSEQQQNKQIGGKAQKVDSDSSKPPETLTDPPGVCQEKVEEKPPPAPTIATKPIRTGPIKPQAIKTEETKS", "length": 2878, "header": "tr|G3X6B2-1|G3X6B2_BOVIN Isoform 1 of Proline rich coiled-coil 2C OS=Bos taurus OX=9913 GN=PRRC2C PE=4 SV=2 CANONICAL=G3X6B2-1" }, "isoforms": [ { "isoform_ac": "A0A3Q1M475-1", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1M475/entry", "sequence": { "sequence": "MSEKSGQSTKAKDGKKYATLSLFNTYKGKSLETQKTTVAARHGLQSLGKVGISRRMPPPANLPSLKAENKGNDPNVNIVPKDGTGWASKQEQHEEEKAPEVPPAQPKPGVAAPPEVAPAPKSWASNKQGGQGDGIQVNSHFQQEFPSLQAAGDQEKKEKEANDDNYGPGPSLRPPNVACWRDGGKSASSSLTSDQDEKPGQDESTAGTSEQSDILKVVEKRIACGPPQAKLNGQQPALASQYRAMMPPYMFQQYPRMAYPPLHGPMRFPPSLSETNKGLRGRGPPPSWASEPERPSILSASELKELDKFDNLDAEADEGWAGAQMEVDYTEQLNFSDDDEQGSSSPKENSSEDQSSKASENTENRKEPDEVSNTKSSSQIPTQPSVAKGPYGKGPPFNQERGPSSHLPPPPKLLAQQHPPPDRQAVPGRPGPFPPKQQVPDEDEIWKQRRRQQSELSAAVERARKRREEEERRMEEQRKAACAEKLKRLDEKLGIVDKQPSPEEIREREREKEREKEWEREKELEKEQEREQEKEREKERERQQEKEKELEREQEKQREMEKERKQEKEKELERQQEKEKELQKTKEQEKECELEKRDREKVDEKTEHKEPTSEPMVEKPESENSCNKEDDPVFTRQDSNRSEKETTQVAHEPEPESGSQPRPAVLSGYFKQFQKSLPPRFQRQQEQMKQQQWQQQQQQGVLPQTVPSQPSGSAVPPPPHRPLYQPMQPHPQHLASMGFDPRWLMMQSYMDPRMISGRPAMDIPPIHPGMIPPKPLMRRDQMEGSPNNSESFEHLARSARDHAISLSEPRMMWGSDPYPHTEPQQATTPKAAEEPEDVRPEAPLDQEQITAAYPVEHGQLEVHPKPDFVRESSETDVQKFLSRSVEDIRPRHTDTNSQSTCFDVPDQKTITTPQEERISAGESQPARKRSVCHGSNHTQKSEELRNEPSANIPKVTSRGIDSKEPAERPEEKPKKEGFIRSSDGPKPEKLYKSKSETRWGPRPSSNRREEGNDRPVRRSGPIKKPILRDMKEEREQRKEKEGEKGEKVTEKVVKPEKTEKKEPLPPPPAPPAAPVQPQSVPPQPQPEPEKLPSVETSPSTLVQKPPQDTEKPLESVSSVEVEPAVKTVNQQAVTAPVVKEEKQPEKVISKDLVTERTRPDSRPTAKKESTLPPRTYWKEARDRDWFPDQGYRGRGRGEYYSRGRSYRGSYGGRGRGGRGHTRDYPQYRDSKPRAEHVAPGPLRQREESETRSESSDFEVVPKRRRQRGSETDTDSEIHESASDKDSLSKSKLPKREERPESKKPIKPQSSFKPENHVRIDNRPLEKSFVRDDDKSKPGFLPKGEPTRRGRGGTFRRGGRDPGGRPSRPSTLRRPAYRDNQWNPRQTEAPKPDSGEPPRRHEQFIPIPADKRPPKFERKFDPARERPRRQRPTRPPRQDKPPRFRRLREREAASKTNEVAVPTNGTVNNVVQEPVNSAGDISGNKTPDLSNQNSSDQANEEWETASESSDFNERRERDEKKNADLNAQVVVKTGENVVPPKREIAKRSFSSQRPGIDRQNRRGNNGPPKSGRNFSGPRNERRSGPPSKGGKRGPFDDQSAGTSGADPVNGSSAHHQEGAPNGTGQKNSKDSTGKKREDPKPGPKKPKEKVDALSQFDLNNYASVVIIDDHPEVTVVEDPQSNLNDDGFTEVVSKKQQKRLQDEERRKKEEQIIQVWNKKNANEKGRNQTSKLPPRFAKKQATGTQQVQPPASALTSAPGPGSTSAPVPATTPAPVPASTPAPLLASPVASVPAPTTVPVLTSTSAPLPALASASVPVPASTPTTAIASSPAPAPTPILASASSPASVPILTSASIPILASALAPASAPPPAISAAAVPASAPTAPTSAPASAPTPTLVQVPVPAPTAPGQTQGQTHKPVQSPLQTTTQSSKQPPPSIRLPSAQTPNGTDYVATGKPIQTSQSHGTLTAELWENKVAPPAVLNDISKKLGPISPPQPPSVSAWNKPLTSFGSATSSEGTKNSQESGVEIGIDTIQFGAPASNGNENEIVPVLSEKTTDKISEPKEQRQKQPRAGPIKAQKLPDLSPVENKEHKPGPIGKERSLKNRKVKDAQQVEPEGQEKPSPATVRSTDPVTTKETKAVSEMSTEIGTMISVSSTEYGTNVKESVTDYTTPSSSLPNTVATNNAKMEDTLVNNVPLPSTLPLPKRETIQQSSSLTSVPPTTFSLTFKMESARKAWENSPNVREKGSPVTSTAPPIASGVSSSASGPSTANYSSFSSASVPQIPVASVTPTTSLSGAGTYTTSSLSTKSTTTSDPPNICKVKPQQLQTSSLPSASHFSQLSCMPSLIAQQQQSPQVYVSQSAAAQIPAFYMDTSHLFNTQHARLAPPSLAQQQGFQPGLSQPTSVQQIPIPIYAPLQGQHQAQLSLGAGPAVSQAQELFSSSLQPYRSQPAFMQSSLSQPSMVLSGTAIHNFPAVQHQELAKAQSGLAFQQTSNTQPIPILYEHQLGQASGLGGSQLIDTHLLQARANLTQASNLYSGQVQQPGQTNFYNTAQSPSALQQVNYGMVTVPLPASQLSLPNFGSTGQPLIALPQTLQPPLQHTAPQAQAQSMSRTAQVSQPFRGLIPAGTQHSMIATTGKMSEMELKAFGSGIDIKPGTPPISGRSTTPTSSPFRATSTSPNSQSSKMNSIVYQKQFQSAPATVRMAQPFPTQFAPQAKQRAEVLQSTQRFFSEQQQNKQIGGKAQKVDSDSSKPPETLTDPPGVCQEKVEEKPPPAPTIATKPIRTGPIKPQAIKTEETKS", "length": 2799, "header": "tr|A0A3Q1M475-1|G3X6B2_BOVIN Computationally mapped isoform of Proline rich coiled-coil 2C OS=Bos taurus OX=9913 GN=PRRC2C PE=4 SV=3 CANONICAL=G3X6B2-1" }, "locus": { "chromosome": "16", "start_pos": 39078807, "end_pos": 39013327, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000083524.3", "url": "https://www.ensembl.org/id/ENSBTAT00000083524.3" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000063031.3", "url": "https://www.ensembl.org/id/ENSBTAP00000063031.3" } ] } }, { "isoform_ac": "A0A3Q1MUN8-1", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1MUN8/entry", "sequence": { "sequence": "MSEKSGQSTKAKDGKKYATLSLFNTYKGKSLETQKTTARHGLQSLGKVGISRRMPPPANLPSLKAENKGNDPNVNIVPKDGTGWASKQEQHEEEKAPEVPPAQPKPGVAAPPEVAPAPKSWASNKQGGQGDGIQVNSHFQQEFPSLQAAGDQEKKEKEANDDNYGPGPSLRPPNVACWRDGGKSASSSLTSDQDEKPGQDESTAGTSEQSDILKVVEKRIACGPPQAKLNGQQPALASQYRAMMPPYMFQQYPRMAYPPLHGPMRFPPSLSETNKGLRGRGPPPSWASEPERPSILSASELKELDKFDNLDAEADEGWAGAQMEVDYTEQLNFSDDDEQGSSSPKENSSEDQSSKASENTENRKEPDEVSNTKSSSQIPTQPSVAKGPYGKGPPFNQERGPSSHLPPPPKLLAQQHPPPDRQAVPGRPGPFPPKQQVPDEDEIWKQRRRQQSELSAAVERARKRREEEERRMEEQRKAACAEKLKRLDEKLGIVDKQPSPEEIREREREKEREKEWEREKELEKEQEREQEKEREKERERQQEKEKELEREQEKQREMEKERKQEKEKELERQQEKEKELQKTKEQEKECELEKRDREKVDEKTEHKEPTSEPMVEKPESENSCNKEDDPVFTRQDSNRSEKETTQVAHEPEPESGSQPRPAVLSGYFKQFQKSLPPRFQRQQEQMKQQQWQQQQQQGVLPQTVPSQPSGSAVPPPPHRPLYQPMQPHPQHLASMGFDPRWLMMQSYMDPRMISGRPAMDIPPIHPGMIPPKPLMRRDQMEGSPNNSESFEHLARSARDHAISLSEPRMMWGSDPYPHTEPQQATTPKAAEEPEDVRPEAPLDQEQITAAYPVEHGQLEVHPKPDFVRESSETDVQKFLSRSVEDIRPRHTDTNSQSTCFDVPDQKTITTPQEERISAGESQPARKRSVCHGSNHTQKSEELRNEPSANIPKVTSRGIDSKEPAERPEEKPKKEGFIRSSDGPKPEKLYKSKSETRWGPRPSSNRREEGNDRPVRRSGPIKKPILRDMKEEREQRKEKEGEKGEKVTEKVVKPEKTEKKEPLPPPPAPPAAPVQPQSVPPQPQPEPEKLPSVETSPSTLVQKPPQDTEKPLESVSSVEVEPAVKTVNQQAVTAPVVKEEKQPEKVISKDLVTERTRPDSRPTAKKESTLPPRTYWKEARDRDWFPDQGYRGRGRGEYYSRGRSYRGSYGGRGRGGRGHTRDYPQYRDSKPRAEHVAPGPLRQREESETRSESSDFEVVPKRRRQRGSETDTDSEIHESASDKDSLSKSKLPKREERPESKKPIKPQSSFKPENHVRIDNRPLEKSFVRDDDKSKPGFLPKGEPTRRGRGGTFRRGGRDPGGRPSRPSTLRRPAYRDNQWNPRQTEAPKPDSGEPPRRHEQFIPIPADKRPPKFERKFDPARERPRRQRPTRPPRQDKPPRFRRLREREAASKTNEVAVPTNGTVNNVVQEPVNSAGDISGNKTPDLSNQNSSDQANEEWETASESSDFNERRERDEKKNADLNAQVVVKTGENVVPPKREIAKRSFSSQRPGIDRQNRRGNNGPPKSGRNFSGPRNERRSGPPSKGGKRGPFDDQSAGTSGADPVNGSSAHHQEGAPNGTGQKNSKDSTGKKREDPKPGPKKPKEKVDALSQFDLNNYASVVIIDDHPEVTVVEDPQSNLNDDGFTEVVSKKQQKRLQDEERRKKEEQIIQVWNKKNANEKGRNQTSKLPPRFAKKQATGTQQVQPPASALTSAPGPGSTSAPVPATTPAPVPASTPAPLLASPVASVPAPTTVPVLTSTSAPLPALASASVPVPASTPTTAIASSPAPAPTPILASASSPASVPILTSASIPILASALAPASAPPPAISAAAVPASAPTAPTSAPASAPTPTLVQVPVPAPTAPGQTQGQTHKPVQSPLQTTTQSSKQPPPSIRLPSAQTPNGTDYVATGKPIQTSQSHGTLTAELWENKVAPPAVLNDISKKLGPISPPQPPSVSAWNKPLTSFGSATSSEGTKNSQESGVEIGIDTIQFGAPASNGNENEIVPVLSEKTTDKISEPKEQRQKQPRAGPIKAQKLPDLSPVENKEHKPGPIGKERSLKNRKVKDAQQVEPEGQEKPSPATVRSTDPVTTKETKAVSEMSTEIGTMISVSSTEYGTNVKESVTDYTTPSSSLPNTVATNNAKMEDTLVNNVPLPSTLPLPKRETIQQSSSLTSVPPTTFSLTFKMESARKAWENSPNVREKGSPVTSTAPPIASGVSSSASGPSTANYSSFSSASVPQIPVASVTPTTSLSGAGTYTTSSLSTKSTTTSDPPNICKVKPQQLQTSSLPSASHFSQLSCMPSLIAQQQQSPQVYVSQSAAAQIPAFYMDTSHLFNTQHARLAPPSLAQQQGFQPGLSQPTSVQQIPIPIYAPLQGQHQAQLSLGAGPAVSQAQELFSSSLQPYRSQPAFMQSSLSQPSMVLSGTAIHNFPAVQHQELAKAQSGLAFQQTSNTQPIPILYEHQLGQASGLGGSQLIDTHLLQARANLTQASNLYSGQVQQPGQTNFYNTAQSPSALQQVTVPLPASQLSLPNFGSTGQPLIALPQTLQPPLQHTAPQAQAQSMSRTAQVSQPFRGLIPAGTQHSMIATTGKMSEMELKAFGSGIDIKPGTPPISGRSTTPTSSPFRQSREQRFFSPRNGSSLNSNRTNR", "length": 2688, "header": "tr|A0A3Q1MUN8-1|G3X6B2_BOVIN Computationally mapped isoform of Proline rich coiled-coil 2C OS=Bos taurus OX=9913 GN=PRRC2C PE=4 SV=2 CANONICAL=G3X6B2-1" }, "locus": { "chromosome": "16", "start_pos": 39078622, "end_pos": 39013327, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000080608.2", "url": "https://www.ensembl.org/id/ENSBTAT00000080608.2" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000058620.2", "url": "https://www.ensembl.org/id/ENSBTAP00000058620.2" } ] } }, { "isoform_ac": "A0AAA9SCK8-1", "url": "https://www.uniprot.org/uniprotkb/A0AAA9SCK8/entry", "sequence": { "sequence": "MSEKSGQSTKAKDGKKYATLSLFNTYKGKSLETQKTTARHGLQSLGKVGISRRMPPPANLPSLKAENKGNDPNVNIVPKDGTGWASKQEQHEEEKAPEVPPAQPKPGVAAPPEVAPAPKSWASNKQGGQGDGIQVNSHFQQEFPSLQAAGDQEKKEKEANDDNYGPGPSLRPPNVACWRDGGKSASSSLTSDQDEKPGQDESTAGTSEQSDILKVVEKRIACGPPQAKLNGQQPALASQYRAMMPPYMFQQYPRMAYPPLHGPMRFPPSLSETNKGLRGRGPPPSWASEPERPSILSASELKELDKFDNLDAEADEGWAGAQMEVDYTEQLNFSDDDEQGSSSPKENSSEDQSSKASENTENRKEPDEVSNTKSSSQIPTQPSVAKGPYGKGPPFNQERGPSSHLPPPPKLLAQQHPPPDRQAVPGRPGPFPPKQQVPDEDEIWKQRRRQQSELSAAVERARKRREEEERRMEEQRKAACAEKLKRLDEKLGIVDKQPSPEEIREREREKEREKEWEREKELEKEQEREQEKEREKERERQQEKEKELEREQEKQREMEKERKQEKEKELERQQEKEKELQKTKEQEKECELEKRDREKVDEKTEHKEPTSEPMVEKPESENSCNKEDDPVFTRQDSNRSEKETTQVAHEPEPESGSQPRPAVLSGYFKQFQKSLPPRFQRQQEQMKQQQWQQQQQQGVLPQTVPSQPSGSAVPPPPHRPLYQPMQPHPQHLASMGFDPRWLMMQSYMDPRMISGRPAMDIPPIHPGMIPPKPLMRRDQMEGSPNNSESFEHLARSARDHAISLSEPRMMWGSDPYPHTEPQQATTPKAAEEPEDVRPEAPLDQEQITAAYPVEHGQLEVHPKPDFVRESSETDVQKFLSRSVEDIRPRHTDTNSQSTCFDVPDQKTITTPQEERISAGESQPARKRSVCHGSNHTQKSEELRNEPSANIPKVTSRGIDSKEPAERPEEKPKKEGFIRSSDGPKPEKLYKSKSETRWGPRPSSNRREEGNDRPVRRSGPIKKPILRDMKEEREQRKEKEGEKGEKVTEKVVKPEKTEKKEPLPPPPAPPAAPVQPQSVPPQPQPEPEKLPSVETSPSTLVQKPPQDTEKPLESVSSVEVEPAVKTVNQQAVTAPVVKEEKQPEKVISKDLVTERTRPDSRPTAKKESTLPPRTYWKEARDRDWFPDQGYRGRGRGEYYSRGRSYRGSYGGRGRGGRGHTRDYPQYRDSKPRAEHVAPGPLRQREESETRSESSDFEVVPKRRRQRGSETDTDSEIHESASDKDSLSKSKLPKREERPESKKPIKPQSSFKPENHVRIDNRPLEKSFVRDDDKSKPGFLPKGEPTRRGRGGTFRRGGRDPGGRPSRPSTLRRPAYRDNQWNPRQTEAPKPDSGEPPRRHEQFIPIPADKRPPKFERKFDPARERPRRQRPTRPPRQDKPPRFRRLREREAASKTNEVAVPTNGTVNNVVQEPVNSAGDISGNKTPDLSNQNSSDQANEEWETASESSDFNERRERDEKKNADLNAQVVVKTGENVVPPKREIAKRSFSSQRPGIDRQNRRGNNGPPKSGRNFSGPRNERRSGPPSKGGKRGPFDDQSAGTSGADPVNGSSAHHQEGAPNGTGQKNSKDSTGKKREDPKPGPKKPKEKVDALSQFDLNNYASVVIIDDHPEVTVVEDPQSNLNDDGFTEVVSKKQQKRLQDEERRKKEEQIIQVWNKKNANEKGRNQTSKLPPRFAKKQATGTQQVQPPASALTSAPGPGSTSAPVPATTPAPVPASTPAPLLASPVASVPAPTTVPVLTSTSAPLPALASASVPVPASTPTTAIASSPAPAPTPILASASSPASVPILTSASIPILASALAPASAPPPAISAAAVPASAPTAPTSAPASAPTPTLVQVPVPAPTAPGQTQGQTHKPVQSPLQTTTQSSKQPPPSIRLPSAQTPNGTDYVATGKPIQTSQSHGTLTAELWENKVAPPAVLNDISKKLGPISPPQPPSVSAWNKPLTSFGSATSSEGTKNSQESGVEIGIDTIQFGAPASNGNENEIVPVLSEKTTDKISEPKEQRQKQPRAGPIKAQKLPDLSPVENKEHKPGPIGKERSLKNRKVKDAQQVEPEGQEKPSPATVRSTDPVTTKETKAVSEMSTEIGTMISVSSTEYGTNVKESVTDYTTPSSSLPNTVATNNAKMEDTLVNNVPLPSTLPLPKRETIQQSSSLTSVPPTTFSLTFKMESARKAWENSPNVREKGSPVTSTAPPIASGVSSSASGPSTANYSSFSSASVPQIPVASVTPTTSLSGAGTYTTSSLSTKSTTTSDPPNICKVKPQQLQTSSLPSASHFSQLSCMPSLIAQQQQSPQVYVSQSAAAQIPAFYMDTSHLFNTQHARLAPPSLAQQQGFQPGLSQPTSVQQIPIPIYAPLQGQHQAQLSLGAGPAVSQAQELFSSSLQPYRSQPAFMQSSLSQPSMVLSGTAIHNFPAVQHQELAKAQSGLAFQQTSNTQPIPILYEHQLGQASGLGGSQLIDTHLLQARANLTQASNLYSGQVQQPGQTNFYNTAQSPSALQQVTVPLPASQLSLPNFGSTGQPLIALPQTLQPPLQHTAPQAQAQSMSRTAQVSQPFRGLIPAGTQHSMIATTGKMSEMELKAFGSGIDIKPGTPPISGRSTTPTSSPFRRELWEEDSATRHLVLGVGKAESRGSSVHATVLL", "length": 2698, "header": "tr|A0AAA9SCK8-1|G3X6B2_BOVIN Computationally mapped isoform of Proline rich coiled-coil 2C OS=Bos taurus OX=9913 GN=PRRC2C PE=4 SV=1 CANONICAL=G3X6B2-1" }, "locus": { "chromosome": "16", "start_pos": 39078599, "end_pos": 39013327, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000123298.1", "url": "https://www.ensembl.org/id/ENSBTAT00000123298.1" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000081607.1", "url": "https://www.ensembl.org/id/ENSBTAP00000081607.1" } ] } }, { "isoform_ac": "A0AAA9TMZ9-1", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TMZ9/entry", "sequence": { "sequence": "MSEKSGQSTKAKDGKKYATLSLFNTYKGKSLETQKTTVAARHGLQSLGKVGISRRMPPPANLPSLKAENKGNDPNVNIVPKDGTGWASKQEQHEEEKAPEVPPAQPKPGVAAPPEVAPAPKSWASNKQGGQGDGIQVNSHFQQEFPSLQAAGDQEKKEKEANDDNYGPGPSLRPPNVACWRDGGKSASSSLTSDQDEKPGQDESTAGTSEQSDILKVVEKRIACGPPQAKLNGQQPALASQYRAMMPPYMFQQYPRMAYPPLHGPMRFPPSLSETNKGLRGRGPPPSWASEPERPSILSASELKELDKFDNLDAEADEGWAGAQMEVDYTEQLNFSDDDEQGSSSPKENSSEDQSSKASENTENRKEPDEVSNTKSSSQIPTQPSVAKGPYGKGPPFNQERGPSSHLPPPPKLLAQQHPPPDRQAVPGRPGPFPPKQQVPDEDEIWKQRRRQQSELSAAVERARKRREEEERRMEEQRKAACAEKLKRLDEKLGIVDKQPSPEEIREREREKEREKEWEREKELEKEQEREQEKEREKERERQQEKEKELEREQEKQREMEKERKQEKEKELERQQEKEKELQKTKEQEKECELEKRDREKVDEKTEHKEPTSEPMVEKPESENSCNKEDDPVFTRQDSNRSEKETTQVAHEPEPESGSQPRPAVLSGYFKQFQKSLPPRFQRQQEQMKQQQWQQQQQQGVLPQTVPSQPSGSAVPPPPHRPLYQPMQPHPQHLASMGFDPRWLMMQSYMDPRMISGRPAMDIPPIHPGMIPPKPLMRRDQMEGSPNNSESFEHLARSARDHAISLSEPRMMWGSDPYPHTEPQQATTPKAAEEPEDVRPEAPLDQEQITAAYPVEHGQLEVHPKPDFVRESSETDVQKFLSRSVEDIRPRHTDTNSQSTCFDVPDQKTITTPQEERISAGESQPARKRSVCHGSNHTQKSEELRNEPSANIPKVTSRGIDSKEPAERPEEKPKKEGFIRSSDGPKPEKLYKSKSETRWGPRPSSNRREEGNDRPVRRSGPIKKPILRDMKEEREQRKEKEGEKGEKVTEKVVKPEKTEKKEPLPPPPAPPAAPVQPQSVPPQPQPEPEKLPSVETSPSTLVQKPPQDTEKPLESVSSVEVEPAVKTVNQQAVTAPVVKEEKQPEKVISKDLVTERTRPDSRPTAKKESTLPPRTYWKEARDRDWFPDQGYRGRGRGEYYSRGRSYRGSYGGRGRGGRGHTRDYPQYRDSKPRAEHVAPGPLRQREESETRSESSDFEVVPKRRRQRGSETDTDSEIHESASDKDSLSKSKLPKREERPESKKPIKPQSSFKPENHVRIDNRPLEKSFVRDDDKSKPGFLPKGEPTRRGRGGTFRRGGRDPGGRPSRPSTLRRPAYRDNQWNPRQTEAPKPDSGEPPRRHEQFIPIPADKRPPKFERKFDPARERPRRQRPTRPPRQDKPPRFRRLREREAASKTNEVAVPTNGTVNNVVQEPVNSAGDISGNKTPDLSNQNSSDQANEEWETASESSDFNERRERDEKKNADLNAQVVVKTGENVVPPKREIAKRSFSSQRPGIDRQNRRGNNGPPKSGRNFSGPRNERRSGPPSKGGKRGPFDDQSAGTSGADPVNGSSAHHQEGAPNGTGQKNSKDSTGKKREDPKPGPKKPKEKVDALSQFDLNNYASVVIIDDHPEVTVVEDPQSNLNDDGFTEVVSKKQQKRLQDEERRKKEEQIIQVWNKKNANEKGRNQTSKLPPRFAKKQATGTQQVQPPASALTSAPGPGSTSAPVPATTPAPVPASTPAPLLASPVASVPAPTTVPVLTSTSAPLPALASASVPVPASTPTTAIASSPAPAPTPILASASSPASVPILTSASIPILASALAPASAPPPAISAAAVPASAPTAPTSAPASAPTPTLVQVPVPAPTAPGQTQGQTHKPVQSPLQTTTQSSKQPPPSIRLPSAQTPNGTDYVATGKPIQTSQSHGTLTAELWENKVAPPAVLNDISKKLGPISPPQPPSVSAWNKPLTSFGSATSSEGTKNSQESGVEIGIDTIQFGAPASNGNENEIVPVLSEKTTDKISEPKEQRQKQPRAGPIKAQKLPDLSPVENKEHKPGPIGKERSLKNRKVKDAQQVEPEGQEKPSPATVRSTDPVTTKETKAVSEMSTEIGTMISVSSTEYGTNVKESVTDYTTPSSSLPNTVATNNAKMEDTLVNNVPLPSTLPLPKRETIQQSSSLTSVPPTTFSLTFKMESARKAWENSPNVREKGSPVTSTAPPIASGVSSSASGPSTANYSSFSSASVPQIPVASVTPTTSLSGAGTYTTSSLSTKSTTTSDPPNICKVKPQQLQTSSLPSASHFSQLSCMPSLIAQQQQSPQVYVSQSAAAQIPAFYMDTSHLFNTQHARLAPPSLAQQQGFQPGLSQPTSVQQIPIPIYAPLQGQHQAQLSLGAGPAVSQAQELFSSSLQPYRSQPAFMQSSLSQPSMVLSGTAIHNFPAVQHQELAKAQSGLAFQQTSNTQPIPILYEHQLGQASGLGGSQLIDTHLLQARANLTQASNLYSGQVQQPGQTNFYNTAQSPSALQQVNYGMVTVPLPASQLSLPNFGSTGQPLIALPQTLQPPLQHTAPQAQAQSMSRTAQVSQPFRGLIPAGTQHSMIATTGKMSEMELKAFGSGIDIKPGTPPISGRSTTPTSSPFRATSTSPNSQSSKMNSIVYQKQFQSAPATVRMAQPFPTQFAPQILSQPNLVPPLVRAPHTNTFPAPVQRPPMALASQMPPPLTTGLMSHARLPHVARGPCGSLSGVRGNQAQAALKAEQDMKKRAVGRGLSHKTFGPRCWQSREQRFFSPRNGSSLNSNRTNR", "length": 2834, "header": "tr|A0AAA9TMZ9-1|G3X6B2_BOVIN Computationally mapped isoform of Proline rich coiled-coil 2C OS=Bos taurus OX=9913 GN=PRRC2C PE=4 SV=1 CANONICAL=G3X6B2-1" }, "locus": { "chromosome": "16", "start_pos": 39078622, "end_pos": 39013327, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000115683.1", "url": "https://www.ensembl.org/id/ENSBTAT00000115683.1" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000099887.1", "url": "https://www.ensembl.org/id/ENSBTAP00000099887.1" } ] } }, { "isoform_ac": "G3X6B2-1", "url": "https://www.uniprot.org/uniprotkb/G3X6B2/entry", "sequence": { "sequence": "MSEKSGQSTKAKDGKKYATLSLFNTYKGKSLETQKTTVAARHGLQSLGKVGISRRMPPPANLPSLKAENKGNDPNVNIVPKDGTGWASKQEQHEEEKAPEVPPAQPKPGVAAPPEVAPAPKSWASNKQGGQGDGIQVNSHFQQEFPSLQAAGDQEKKEKEANDDNYGPGPSLRPPNVACWRDGGKSASSSLTSDQDEKPGQDESTAGTSEQSDILKVVEKRIACGPPQAKLNGQQPALASQYRAMMPPYMFQQYPRMAYPPLHGPMRFPPSLSETNKGLRGRGPPPSWASEPERPSILSASELKELDKFDNLDAEADEGWAGAQMEVDYTEQLNFSDDDEQGSSSPKENSSEDQSSKASENTENRKEPDEVSNTKSSSQIPTQPSVAKGPYGKGPPFNQERGPSSHLPPPPKLLAQQHPPPDRQAVPGRPGPFPPKQQVPDEDEIWKQRRRQQSELSAAVERARKRREEEERRMEEQRKAACAEKLKRLDEKLGIVDKQPSPEEIREREREKEREKEWEREKELEKEQEREQEKEREKERERQQEKEKELEREQEKQREMEKERKQEKEKELERQQEKEKELQKTKEQEKECELEKRDREKVDEKTEHKEPTSEPMVEKPESENSCNKEDDPVFTRQDSNRSEKETTQVAHEPEPESGSQPRPAVLSGYFKQFQKSLPPRFQRQQEQMKQQQWQQQQQQGVLPQTVPSQPSGSAVPPPPHRPLYQPMQPHPQHLASMGFDPRWLMMQSYMDPRMISGRPAMDIPPIHPGMIPPKPLMRRDQMEGSPNNSESFEHLARSARDHAISLSEPRMMWGSDPYPHTEPQQATTPKAAEEPEDVRPEAPLDQEQITAAYPVEHGQLEVHPKPDFVRESSETDVQKFLSRSVEDIRPRHTDTNSQSTCFDVPDQKTITTPQEERISAGESQPARKRSVCHGSNHTQKSEELRNEPSANIPKVTSRGIDSKEPAERPEEKPKKEGFIRSSDGPKPEKLYKSKSETRWGPRPSSNRREEGNDRPVRRSGPIKKPILRDMKEEREQRKEKEGEKGEKVTEKVVKPEKTEKKEPLPPPPAPPAAPVQPQSVPPQPQPEPEKLPSVETSPSTLVQKPPQDTEKPLESVSSVEVEPAVKTVNQQAVTAPVVKEEKQPEKVISKDLVTERTRPDSRPTAKKESTLPPRTYWKEARDRDWFPDQGYRGRGRGEYYSRGRSYRGSYGGRGRGGRGHTRDYPQYRDSKPRAEHVAPGPLRQREESETRSESSDFEVVPKRRRQRGSETDTDSEIHESASDKDSLSKSKLPKREERPESKKPIKPQSSFKPENHVRIDNRPLEKSFVRDDDKSKPGFLPKGEPTRRGRGGTFRRGGRDPGGRPSRPSTLRRPAYRDNQWNPRQTEAPKPDSGEPPRRHEQFIPIPADKRPPKFERKFDPARERPRRQRPTRPPRQDKPPRFRRLREREAASKTNEVAVPTNGTVNNVVQEPVNSAGDISGNKTPDLSNQNSSDQANEEWETASESSDFNERRERDEKKNADLNAQVVVKTGENVVPPKREIAKRSFSSQRPGIDRQNRRGNNGPPKSGRNFSGPRNERRSGPPSKGGKRGPFDDQSAGTSGADPVNGSSAHHQEGAPNGTGQKNSKDSTGKKREDPKPGPKKPKEKVDALSQFDLNNYASVVIIDDHPEVTVVEDPQSNLNDDGFTEVVSKKQQKRLQDEERRKKEEQIIQVWNKKNANEKGRNQTSKLPPRFAKKQATGTQQVQPPASALTSAPGPGSTSAPVPATTPAPVPASTPAPLLASPVASVPAPTTVPVLTSTSAPLPALASASVPVPASTPTTAIASSPAPAPTPILASASSPASVPILTSASIPILASALAPASAPPPAISAAAVPASAPTAPTSAPASAPTPTLVQVPVPAPTAPGQTQGQTHKPVQSPLQTTTQSSKQPPPSIRLPSAQTPNGTDYVATGKPIQTSQSHGTLTAELWENKVAPPAVLNDISKKLGPISPPQPPSVSAWNKPLTSFGSATSSEGTKNSQESGVEIGIDTIQFGAPASNGNENEIVPVLSEKTTDKISEPKEQRQKQPRAGPIKAQKLPDLSPVENKEHKPGPIGKERSLKNRKVKDAQQVEPEGQEKPSPATVRSTDPVTTKETKAVSEMSTEIGTMISVSSTEYGTNVKESVTDYTTPSSSLPNTVATNNAKMEDTLVNNVPLPSTLPLPKRETIQQSSSLTSVPPTTFSLTFKMESARKAWENSPNVREKGSPVTSTAPPIASGVSSSASGPSTANYSSFSSASVPQIPVASVTPTTSLSGAGTYTTSSLSTKSTTTSDPPNICKVKPQQLQTSSLPSASHFSQLSCMPSLIAQQQQSPQVYVSQSAAAQIPAFYMDTSHLFNTQHARLAPPSLAQQQGFQPGLSQPTSVQQIPIPIYAPLQGQHQAQLSLGAGPAVSQAQELFSSSLQPYRSQPAFMQSSLSQPSMVLSGTAIHNFPAVQHQELAKAQSGLAFQQTSNTQPIPILYEHQLGQASGLGGSQLIDTHLLQARANLTQASNLYSGQVQQPGQTNFYNTAQSPSALQQVNYGMVTVPLPASQLSLPNFGSTGQPLIALPQTLQPPLQHTAPQAQAQSMSRTAQVSQPFRGLIPAGTQHSMIATTGKMSEMELKAFGSGIDIKPGTPPISGRSTTPTSSPFRATSTSPNSQSSKMNSIVYQKQFQSAPATVRMAQPFPTQFAPQILSQPNLVPPLVRAPHTNTFPAPVQRPPMALASQMPPPLTTGLMSHARLPHVARGPCGSLSGVRGNQAQAALKAEQDMKAKQRAEVLQSTQRFFSEQQQNKQIGGKAQKVDSDSSKPPETLTDPPGVCQEKVEEKPPPAPTIATKPIRTGPIKPQAIKTEETKS", "length": 2878, "header": "tr|G3X6B2-1|G3X6B2_BOVIN Isoform 1 of Proline rich coiled-coil 2C OS=Bos taurus OX=9913 GN=PRRC2C PE=4 SV=2 CANONICAL=G3X6B2-1" }, "locus": { "chromosome": "16", "start_pos": 39078807, "end_pos": 39013327, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000002380.7", "url": "https://www.ensembl.org/id/ENSBTAT00000002380.7" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000002380.6", "url": "https://www.ensembl.org/id/ENSBTAP00000002380.6" } ] } }, { "isoform_ac": "G3X6B3-1", "url": "https://www.uniprot.org/uniprotkb/G3X6B3/entry", "sequence": { "sequence": "MSEKSGQSTKAKDGKKYATLSLFNTYKGKSLETQKTTVAARHGLQSLGKVGISRRMPPPANLPSLKAENKGNDPNVNIVPKDGTGWASKQEQHEEEKAPEVPPAQPKPGVAAPPEVAPAPKSWASNKQGGQGDGIQVNSHFQQEFPSLQAAGDQEKKEKEANDDNYGPGPSLRPPNVACWRDGGKSASSSLTSDQDEKPGQDESTAGTSEQSDILKVVEKRIACGPPQAKLNGQQPALASQYRAMMPPYMFQQYPRMAYPPLHGPMRFPPSLSETNKGLRGRGPPPSWASEPERPSILSASELKELDKFDNLDAEADEGWAGAQMEVDYTEQLNFSDDDEQGSSSPKENSSEDQSSKASENTENRKEPDEVSNTKSSSQIPTQPSVAKGPYGKGPPFNQERGPSSHLPPPPKLLAQQHPPPDRQAVPGRPGPFPPKQQVPDEDEIWKQRRRQQSELSAAVERARKRREEEERRMEEQRKAACAEKLKRLDEKLGIVDKQPSPEEIREREREKEREKEWEREKELEKEQEREQEKEREKERERQQEKEKELEREQEKQREMEKERKQEKEKELERQQEKEKELQKTKEQEKECELEKRDREKVDEKTEHKEPTSEPMVEKPESENSCNKEDDPVFTRQDSNRSEKETTQVAHEPEPESGSQPRPAVLSGYFKQFQKSLPPRFQRQQEQMKQQQWQQQQQQGVLPQTVPSQPSGSAVPPPPHRPLYQPMQPHPQHLASMGFDPRWLMMQSYMDPRMISGRPAMDIPPIHPGMIPPKPLMRRDQMEGSPNNSESFEHLARSARDHAISLSEPRMMWGSDPYPHTEPQQATTPKAAEEPEDVRPEAPLDQEQITAAYPVEHGQLEVHPKPDFVRESSETDVQKFLSRSVEDIRPRHTDTNSQSTCFDVPDQKTITTPQEERISAGESQPARKRSVCHGSNHTQKSEELRNEPSANIPKVTSRGIDSKEPAERPEEKPKKEGFIRSSDGPKPEKLYKSKSETRWGPRPSSNRREEGNDRPVRRSGPIKKPILRDMKEEREQRKEKEGEKGEKVTEKVVKPEKTEKKEPLPPPPAPPAAPVQPQSVPPQPQPEPEKLPSVETSPSTLVQKPPQDTEKPLESVSSVEVEPAVKTVNQQAVTAPVVKEEKQPEKVISKDLVTERTRPDSRPTAKKESTLPPRTYWKEARDRDWFPDQGYRGRGRGEYYSRGRSYRGSYGGRGRGGRGHTRDYPQYRDSKPRAEHVAPGPLRQREESETRSESSDFEVVPKRRRQRGSETDTDSEIHESASDKDSLSKSKLPKREERPESKKPIKPQSSFKPENHVRIDNRPLEKSFVRDDDKSKPGFLPKGEPTRRGRGGTFRRGGRDPGGRPSRPSTLRRPAYRDNQWNPRQTEAPKPDSGEPPRRHEQFIPIPADKRPPKFERKFDPARERPRRQRPTRPPRQDKPPRFRRLREREAASKTNEVAVPTNGTVNNVVQEPVNSAGDISGNKTPDLSNQNSSDQANEEWETASESSDFNERRERDEKKNADLNAQVVVKTGENVVPPKREIAKRSFSSQRPGIDRQNRRGNNGPPKSGRNFSGPRNERRSGPPSKGGKRGPFDDQSAGTSGADPVNGSSAHHQEGAPNGTGQKNSKDSTGKKREDPKPGPKKPKEKVDALSQFDLNNYASVVIIDDHPEVTVVEDPQSNLNDDGFTEVVSKKQQKRLQDEERRKKEEQIIQVWNKKNANEKGRNQTSKLPPRFAKKQATGTQQVQPPASALTSAPGPGSTSAPVPATTPAPVPASTPAPLLASPVASVPAPTTVPVLTSTSAPLPALASASVPVPASTPTTAIASSPAPAPTPILASASSPASVPILTSASIPILASALAPASAPPPAISAAAVPASAPTAPTSAPASAPTPTLVQVPVPAPTAPGQTQGQTHKPVQSPLQTTTQSSKQPPPSIRLPSAQTPNGTDYVATGKPIQTSQSHGTLTAELWENKVAPPAVLNDISKKLGPISPPQPPSVSAWNKPLTSFGSATSSEGTKNSQESGVEIGIDTIQFGAPASNGNENEIVPVLSEKTTDKISEPKEQRQKQPRAGPIKAQKLPDLSPVENKEHKPGPIGKERSLKNRKVKDAQQVEPEGQEKPSPATVRSTDPVTTKETKAVSEMSTEIGTMISVSSTEYGTNVKESVTDYTTPSSSLPNTVATNNAKMEDTLVNNVPLPSTLPLPKRETIQQSSSLTSVPPTTFSLTFKMESARKAWENSPNVREKGSPVTSTAPPIASGVSSSASGPSTANYSSFSSASVPQIPVASVTPTTSLSGAGTYTTSSLSTKSTTTSDPPNICKVKPQQLQTSSLPSASHFSQLSCMPSLIAQQQQSPQVYVSQSAAAQIPAFYMDTSHLFNTQHARLAPPSLAQQQGFQPGLSQPTSVQQIPIPIYAPLQGQHQAQLSLGAGPAVSQAQELFSSSLQPYRSQPAFMQSSLSQPSMVLSGTAIHNFPAVQHQELAKAQSGLAFQQTSNTQPIPILYEHQLGQASGLGGSQLIDTHLLQARANLTQASNLYSGQVQQPGQTNFYNTAQSPSALQQVNYGMVTVPLPASQLSLPNFGSTGQPLIALPQTLQPPLQHTAPQAQAQSMSRTAQVSQPFRGLIPAGTQHSMIATTGKMSEMELKAFGSGIDIKPGTPPISGRSTTPTSSPFRATSTSPNSQSSKMNSIVYQKQFQSAPATVRMAQPFPTQFAPQKRAVGRGLSHKTFGPRCWQSREQRFFSPRNGSSLNSNRTNR", "length": 2755, "header": "tr|G3X6B3-1|G3X6B3_BOVIN Computationally mapped isoform of Proline rich coiled-coil 2C OS=Bos taurus OX=9913 GN=PRRC2C PE=4 SV=2 CANONICAL=G3X6B2-1" }, "locus": { "chromosome": "16", "start_pos": 39078622, "end_pos": 39013327, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000002381.7", "url": "https://www.ensembl.org/id/ENSBTAT00000002381.7" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000002381.6", "url": "https://www.ensembl.org/id/ENSBTAP00000002381.6" } ] } } ], "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "other", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 1778, "start_aa": "Thr", "end_pos": 1778, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr1778", "evidence": [ { "id": "", "database": "GlyGen", "url": "https://data.glygen.org/" } ], "filter_code": "000000000000000010000.00000000001000.0.01000" }, { "glytoucan_ac": "", "type": "O-linked", "subtype": "other", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 1834, "start_aa": "Thr", "end_pos": 1834, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr1834", "evidence": [ { "id": "", "database": "GlyGen", "url": "https://data.glygen.org/" } ], "filter_code": "000000000000000010000.00000000001000.0.01000" }, { "glytoucan_ac": "", "type": "O-linked", "subtype": "other", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 1893, "start_aa": "Thr", "end_pos": 1893, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr1893", "evidence": [ { "id": "", "database": "GlyGen", "url": "https://data.glygen.org/" } ], "filter_code": "000000000000000010000.00000000001000.0.01000" }, { "glytoucan_ac": "", "type": "O-linked", "subtype": "other", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 1905, "start_aa": "Thr", "end_pos": 1905, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr1905", "evidence": [ { "id": "", "database": "GlyGen", "url": "https://data.glygen.org/" } ], "filter_code": "000000000000000010000.00000000001000.0.01000" }, { "glytoucan_ac": "", "type": "O-linked", "subtype": "other", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 2290, "start_aa": "Thr", "end_pos": 2290, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr2290", "evidence": [ { "id": "", "database": "GlyGen", "url": "https://data.glygen.org/" } ], "filter_code": "000000000000000010000.00000000001000.0.01000" }, { "glytoucan_ac": "", "type": "O-linked", "subtype": "other", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 2855, "start_aa": "Thr", "end_pos": 2855, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr2855", "evidence": [ { "id": "", "database": "GlyGen", "url": "https://data.glygen.org/" } ], "filter_code": "000000000000000010000.00000000001000.0.01000" } ], "phosphorylation": [], "glycation": [], "keywords": [ "glycoprotein", "glycoprotein_predicted" ], "publication": [], "pathway": [], "orthologs": [ { "uniprot_canonical_ac": "Q9Y520-1", "protein_name": "Protein PRRC2C", "gene_name": "PRRC2C", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": 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"length": 2896 }, "evidence": [ { "id": "G3X6B2", "url": "https://omabrowser.org/oma/group/G3X6B2/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" } ], "go_annotation": { "categories": [ { "name": "Biological Process", "total": 2, "go_terms": [ { "name": "hematopoietic progenitor cell differentiation", "id": "GO:0002244", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0002244", "evidence": [ { "database": "UniProtKB", "id": "G3X6B2", "url": "https://www.uniprot.org/uniprotkb/G3X6B2" } ], "pmid": "" }, { "name": "stress granule assembly", "id": "GO:0034063", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0034063", "evidence": [ { "database": "UniProtKB", "id": "G3X6B2", "url": "https://www.uniprot.org/uniprotkb/G3X6B2" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 1, "go_terms": [ { "name": "cytosol", "id": "GO:0005829", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005829", "evidence": [ { "database": "UniProtKB", "id": "G3X6B2", "url": 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"glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ], "tool_support": { "graph_view": "yes" } }, { "uniprot_canonical_ac": "F6RZU2-1", "uniprot_ac": "F6RZU2", "uniprot_id": "F6RZU2_BOVIN", "mass": { "chemical_mass": 43023.0, "monoisotopic_mass": 43023.0 }, "refseq": { "ac": "XP_024838192", "name": "Krueppel-like factor 15 isoform X1", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_024838192" }, "gene_names": [ { "name": "KLF15", "type": "recommended", "evidence": [ { "id": "F6RZU2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F6RZU2" } ] }, { "name": "KLF15", "type": "synonym", "evidence": [ { "id": "XP_024838192", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_024838192" } ] } ], "protein_names": [ { "name": "Krueppel-like factor 15", "type": "recommended", "evidence": [ { "id": "F6RZU2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F6RZU2/entry#names_and_taxonomy" } ] }, { "name": "Krueppel-like factor 15 isoform X1", "type": "synonym", "evidence": [ { "id": "XP_024838192", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_024838192" } ] } ], "function": [], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Bos taurus", "taxid": 9913, "evidence": [ { "database": "UniProtKB", "id": "F6RZU2", "url": "https://www.uniprot.org/uniprotkb/F6RZU2" } ], "common_name": "Bovine", "glygen_name": "Bovine", "reference_species": "Bos taurus [9913]" } ], "gene": [ { "name": "KLF15", "url": "https://www.uniprot.org/uniprotkb/F6RZU2", "locus": { "chromosome": "22", "start_pos": 60648854, "end_pos": 60606367, "strand": "-", "evidence": [ { "database": "Ensembl Gene", "id": "ENSBTAG00000008313", "url": "https://www.ensembl.org/id/ENSBTAG00000008313" } ] } } ], "crossref": [ { "id": "F6RZU2", "url": "https://alphafold.ebi.ac.uk/entry/F6RZU2", "database": "AlphaFoldDB", "categories": [] }, { "id": "ENSBTAG00000008313", "url": "https://bgee.org/?page=gene&gene_id=ENSBTAG00000008313", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "cd21580", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd21580", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "407241", "url": "https://www.ncbi.nlm.nih.gov/gene/407241", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR013087", "url": "https://www.ebi.ac.uk/interpro/entry/IPR013087", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR036236", "url": "https://www.ebi.ac.uk/interpro/entry/IPR036236", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "VQIQPIR", "url": "https://omabrowser.org/oma/group/VQIQPIR/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "A0A3Q1M5Q0", "url": "https://www.orthodb.org/?gene=A0A3Q1M5Q0", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A3Q1NFN4", "url": "https://www.orthodb.org/?gene=A0A3Q1NFN4", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR23235", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR23235", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR23235:SF44", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR23235:SF44", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00096", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00096", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "XP_024838192", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_024838192", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A3Q1M5Q0", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1M5Q0", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A3Q1M5Q0-1", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1M5Q0-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A3Q1NFN4", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1NFN4", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A3Q1NFN4-1", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1NFN4-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0AAA9SA02", "url": "https://www.uniprot.org/uniprotkb/A0AAA9SA02", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0AAA9SA02-1", "url": "https://www.uniprot.org/uniprotkb/A0AAA9SA02-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0AAA9SAJ5", "url": "https://www.uniprot.org/uniprotkb/A0AAA9SAJ5", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0AAA9SAJ5-1", "url": "https://www.uniprot.org/uniprotkb/A0AAA9SAJ5-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0AAA9SCF6", "url": "https://www.uniprot.org/uniprotkb/A0AAA9SCF6", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0AAA9SCF6-1", "url": "https://www.uniprot.org/uniprotkb/A0AAA9SCF6-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0AAA9TPS7", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TPS7", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0AAA9TPS7-1", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TPS7-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0AAA9TZW5", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TZW5", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0AAA9TZW5-1", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TZW5-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "F6RZU2", "url": "https://www.uniprot.org/uniprotkb/F6RZU2", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "F6RZU2-1", "url": "https://www.uniprot.org/uniprotkb/F6RZU2-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MVDHLLPVDETFSSLKRPICFLGDGRAYHMLPSPLSEDDSDASSLCSCASPDSQTLCSCYGGGRGAEGQDSILDFLLSQATLGSGVAAHGSPMAWGTWRKTPGPVKGEHFSFPEFPVGNPDDVPRPFQPTLEEIEEFLEENMEPAVKQAPEGSGKDLDTCGQLSTGPHRGHLHPGASGRERCAPPPGAGAAGSQGPAGAPAPDPPVPLLLQIQPVPVKQESGAEPASPGQPPEAVRVAQLLVSIQGQTFTLVPQVLPSSSLSLPSKFVRIAPVPIAAKPLGSGPLGPGSTGLLVGQKFPKNPAAELIKMHRCTFPGCSKMYTKSSHLKAHLRRHTGEKPFACTWPGCGWRFSRSDELSRHRRSHSGVKPYQCPVCEKKFARSDHLSKHVKVHRFPRSSRLPRP", "length": 403, "header": "tr|F6RZU2-1|F6RZU2_BOVIN Isoform 1 of Krueppel-like factor 15 OS=Bos taurus OX=9913 GN=KLF15 PE=4 SV=1 CANONICAL=F6RZU2-1" }, "isoforms": [ { "isoform_ac": "A0A3Q1M5Q0-1", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1M5Q0/entry", "sequence": { "sequence": "MVDHLLPVDETFSSLKRPICFLGDGRAYHMLPSPLSEDDSDASSLCSCASPDSQTLCSCYGGGRGAEGQDSILDFLLSQATLGSGVAAHGSPMAWGTWRKTPGPVKGEHFSFPEFPVGNPDDVPRPFQPTLEEIEEFLEENMEPAVKQAPEGSGKDLDTCGQLSTGPHRGHLHPGASGRERCAPPPGAGAAGSQGPAGAPAPDPPVPLLLQIQPVPVKQESGAEPASPGQPPEAVRVAQLLVSIQGQTFTLVPQVLPSSSLSLPSKFVRIAPVPIAAKPLGSGPLGPGSTGLLVGQKFPKNPAAELIKMHRCTFPGCSKMYTKSSHLKAHLRRHTGEKPFACTWPGCGWRHQNPCPMGELNCVLPTRCGPQTGWNQKVGDADPGYLTIGRMSMR", "length": 394, "header": "tr|A0A3Q1M5Q0-1|F6RZU2_BOVIN Computationally mapped isoform of Krueppel-like factor 15 OS=Bos taurus OX=9913 GN=KLF15 PE=4 SV=2 CANONICAL=F6RZU2-1" }, "locus": { "chromosome": "22", "start_pos": 60648782, "end_pos": 60616031, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000073751.2", "url": "https://www.ensembl.org/id/ENSBTAT00000073751.2" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000063598.2", "url": "https://www.ensembl.org/id/ENSBTAP00000063598.2" } ] } }, { "isoform_ac": "A0A3Q1NFN4-1", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1NFN4/entry", "sequence": { "sequence": "MVDHLLPVDETFSSLKRPICFLGDGRAYHMLPSPLSEDDSDASSLCSCASPDSQTLCSCYGGGRGAEGQDSILDFLLSQATLGSGVAAHGSPMAWGTWRKTPGPVKGEHFSFPEFPVGNPDDVPRPFQPTLEEIEEFLEENMEPAVKQAPEGSGKDLDTCGQLSTGPHRGHLHPGASGRERCAPPPGAGAAGSQGPAGAPAPDPPVPLLLQIQPVPVKQESGAEPASPGQPPEAVRVAQLLVSIQGQTFTLVPQVLPSSSLSLPSKFVRIAPVPIAAKPLGSGPLGPGSTGLLVGQKFPKNPAAELIKMHRCTFPGCSKMYTKSSHLKAHLRRHTGEKPFACTWPGCGWSPAMGIVVDTHQGPARARGPCTRSAPSVLAPGSRARTSCRDTGVRTRA", "length": 397, "header": "tr|A0A3Q1NFN4-1|F6RZU2_BOVIN Computationally mapped isoform of Krueppel-like factor 15 OS=Bos taurus OX=9913 GN=KLF15 PE=4 SV=2 CANONICAL=F6RZU2-1" }, "locus": { "chromosome": "22", "start_pos": 60623597, "end_pos": 60616031, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000069182.2", "url": "https://www.ensembl.org/id/ENSBTAT00000069182.2" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000070485.2", "url": "https://www.ensembl.org/id/ENSBTAP00000070485.2" } ] } }, { "isoform_ac": "A0AAA9SA02-1", "url": "https://www.uniprot.org/uniprotkb/A0AAA9SA02/entry", "sequence": { "sequence": "MVDHLLPVDETFSSLKRPICFLGDGRAYHMLPSPLSEDDSDASSLCSCASPDSQTLCSCYGGGRGAEGQDSILDFLLSQATLGSGVAAHGSPMAWGTWRKTPGPVKGEHFSFPEFPVGNPDDVPRPFQPTLEEIEEFLEENMEPAVKQAPEGSGKDLDTCGQLSTGPHRGHLHPGASGRERCAPPPGAGAAGSQGPAGAPAPDPPVPLLLQIQPVPVKQESGAEPASPGQPPEAVRVAQLLVSIQGQTFTLVPQVLPSSSLSLPSKFVRIAPVPIAAKPLGSGPLGPGSTGLLVGQKFPKNPAAELIKMHRCTFPGCSKMYTKSSHLKAHLRRHTGEKPFACTWPGCGWRHPPTRGRLPCVSTVASETSLGRSTRTSRLHWKREDPEDQDGPAFAWGYTGSHRAIRPPRGPCPHALPGVASPAELVLAP", "length": 429, "header": "tr|A0AAA9SA02-1|F6RZU2_BOVIN Computationally mapped isoform of Krueppel-like factor 15 OS=Bos taurus OX=9913 GN=KLF15 PE=4 SV=1 CANONICAL=F6RZU2-1" }, "locus": { "chromosome": "22", "start_pos": 60621591, "end_pos": 60616031, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000112676.1", "url": "https://www.ensembl.org/id/ENSBTAT00000112676.1" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000082139.1", "url": "https://www.ensembl.org/id/ENSBTAP00000082139.1" } ] } }, { "isoform_ac": "A0AAA9SAJ5-1", "url": "https://www.uniprot.org/uniprotkb/A0AAA9SAJ5/entry", "sequence": { "sequence": "MVDHLLPVDETFSSLKRPICFLGDGRAYHMLPSPLSEDDSDASSLCSCASPDSQTLCSCYGGGRGAEGQDSILDFLLSQATLGSGVAAHGSPMAWGTWRKTPGPVKGEHFSFPEFPVGNPDDVPRPFQPTLEEIEEFLEENMEPAVKQAPEGSGKDLDTCGQLSTGPHRGHLHPGASGRERCAPPPGAGAAGSQGPAGAPAPDPPVPLLLQIQPVPVKQESGAEPASPGQPPEAVRVAQLLVSIQGQTFTLVPQVLPSSSLSLPSKFVRIAPVPIAAKPLGSGPLGPGSTGLLVGQKFPKNPAAELIKMHRCTFPGCSKMYTKSSHLKAHLRRHTGEKPFACTWPGCGWRDPVPSEESALLPPLLGQWWGPGLHGARGG", "length": 379, "header": "tr|A0AAA9SAJ5-1|F6RZU2_BOVIN Computationally mapped isoform of Krueppel-like factor 15 OS=Bos taurus OX=9913 GN=KLF15 PE=4 SV=1 CANONICAL=F6RZU2-1" }, "locus": { "chromosome": "22", "start_pos": 60620843, "end_pos": 60616031, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000093949.1", "url": "https://www.ensembl.org/id/ENSBTAT00000093949.1" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000082360.1", "url": "https://www.ensembl.org/id/ENSBTAP00000082360.1" } ] } }, { "isoform_ac": "A0AAA9SCF6-1", "url": "https://www.uniprot.org/uniprotkb/A0AAA9SCF6/entry", "sequence": { "sequence": "MVDHLLPVDETFSSLKRPICFLGDGRAYHMLPSPLSEDDSDASSLCSCASPDSQTLCSCYGGGRGAEGQDSILDFLLSQATLGSGVAAHGSPMAWGTWRKTPGPVKGEHFSFPEFPVGNPDDVPRPFQPTLEEIEEFLEENMEPAVKQAPEGSGKDLDTCGQLSTGPHRGHLHPGASGRERCAPPPGAGAAGSQGPAGAPAPDPPVPLLLQIQPVPVKQESGAEPASPGQPPEAVRVAQLLVSIQGQTFTLVPQVLPSSSLSLPSKFVRIAPVPIAAKPLGSGPLGPGSTGLLVGQKFPKNPAAELIKMHRCTFPGCSKMYTKSSHLKAHLRRHTGEKPFACTWPGCGWSPAMGIVVDTHQGPARARGPCTRSAPSVLAPGIPRPEAACLVCPLWPLRRASEGQQEPQGSTGRERTLRTRTGPHLLGATRARTEPSGLPAAPVLTPSPGWRLQRSWSWLPEWEGEADPVLRAGGGGGWGLSRSLLAAALGALTPAGVGGPGLAPDGRNLGAPSNRLSCRGAGHPAHSGGGQAARGHQDGKTWVWPLLLWPRPLCGR", "length": 556, "header": "tr|A0AAA9SCF6-1|F6RZU2_BOVIN Computationally mapped isoform of Krueppel-like factor 15 OS=Bos taurus OX=9913 GN=KLF15 PE=4 SV=1 CANONICAL=F6RZU2-1" }, "locus": { "chromosome": "22", "start_pos": 60621880, "end_pos": 60616031, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000130811.1", "url": "https://www.ensembl.org/id/ENSBTAT00000130811.1" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000081556.1", "url": "https://www.ensembl.org/id/ENSBTAP00000081556.1" } ] } }, { "isoform_ac": "A0AAA9TPS7-1", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TPS7/entry", "sequence": { "sequence": "MVDHLLPVDETFSSLKRPICFLGDGRAYHMLPSPLSEDDSDASSLCSCASPDSQTLCSCYGGGRGAEGQDSILDFLLSQATLGSGVAAHGSPMAWGTWRKTPGPVKGEHFSFPEFPVGNPDDVPRPFQPTLEEIEEFLEENMEPAVKQAPEGSGKDLDTCGQLSTGPHRGHLHPGASGRERCAPPPGAGAAGSQGPAGAPAPDPPVPLLLQIQPVPVKQESGAEPASPGQPPEAVRVAQLLVSIQGQTFTLVPQVLPSSSLSLPSKFVRIAPVPIAAKPLGSGPLGPGSTGLLVGQKFPKNPAAELIKMHRCTFPGCSKMYTKSSHLKAHLRRHTGEKPFACTWPGCGWRCCCVCSLTDAQTKHPRHQVLGWPRGTCFSSWS", "length": 382, "header": "tr|A0AAA9TPS7-1|F6RZU2_BOVIN Computationally mapped isoform of Krueppel-like factor 15 OS=Bos taurus OX=9913 GN=KLF15 PE=4 SV=2 CANONICAL=F6RZU2-1" }, "locus": { "chromosome": "22", "start_pos": 60622691, "end_pos": 60616031, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000125115.2", "url": "https://www.ensembl.org/id/ENSBTAT00000125115.2" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000099024.2", "url": "https://www.ensembl.org/id/ENSBTAP00000099024.2" } ] } }, { "isoform_ac": "A0AAA9TZW5-1", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TZW5/entry", "sequence": { "sequence": "MVDHLLPVDETFSSLKRPICFLGDGRAYHMLPSPLSEDDSDASSLCSCASPDSQTLCSCYGGGRGAEGQDSILDFLLSQATLGSGVAAHGSPMAWGTWRKTPGPVKGEHFSFPEFPVGNPDDVPRPFQPTLEEIEEFLEENMEPAVKQAPEGSGKDLDTCGQLSTGPHRGHLHPGASGRERCAPPPGAGAAGSQGPAGAPAPDPPVPLLLQIQPVPVKQESGAEPASPGQPPEAVRVAQLLVSIQGQTFTLVPQVLPSSSLSLPSKFVRIAPVPIAAKPLGSGPLGPGSTGLLVGQKFPKNPAAELIKMHRCTFPGCSKMYTKSSHLKAHLRRHTGEKPFACTWPGCGWRSVWRRRPGIAQGLRASAPGVRGQDRVLCAWIRLLRAGRGWAGPEVPLCLRVLEYSFMVTR", "length": 410, "header": "tr|A0AAA9TZW5-1|A0AAA9TZW5_BOVIN Computationally mapped isoform of KLF transcription factor 15 OS=Bos taurus OX=9913 GN=KLF15 PE=4 SV=1 CANONICAL=F6RZU2-1" }, "locus": { "chromosome": "22", "start_pos": 60617260, "end_pos": 60616031, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000124402.1", "url": "https://www.ensembl.org/id/ENSBTAT00000124402.1" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000102305.1", "url": "https://www.ensembl.org/id/ENSBTAP00000102305.1" } ] } }, { "isoform_ac": "F6RZU2-1", "url": "https://www.uniprot.org/uniprotkb/F6RZU2/entry", "sequence": { "sequence": "MVDHLLPVDETFSSLKRPICFLGDGRAYHMLPSPLSEDDSDASSLCSCASPDSQTLCSCYGGGRGAEGQDSILDFLLSQATLGSGVAAHGSPMAWGTWRKTPGPVKGEHFSFPEFPVGNPDDVPRPFQPTLEEIEEFLEENMEPAVKQAPEGSGKDLDTCGQLSTGPHRGHLHPGASGRERCAPPPGAGAAGSQGPAGAPAPDPPVPLLLQIQPVPVKQESGAEPASPGQPPEAVRVAQLLVSIQGQTFTLVPQVLPSSSLSLPSKFVRIAPVPIAAKPLGSGPLGPGSTGLLVGQKFPKNPAAELIKMHRCTFPGCSKMYTKSSHLKAHLRRHTGEKPFACTWPGCGWRFSRSDELSRHRRSHSGVKPYQCPVCEKKFARSDHLSKHVKVHRFPRSSRLPRP", "length": 403, "header": "tr|F6RZU2-1|F6RZU2_BOVIN Isoform 1 of Krueppel-like factor 15 OS=Bos taurus OX=9913 GN=KLF15 PE=4 SV=1 CANONICAL=F6RZU2-1" }, "locus": { "chromosome": "22", "start_pos": 60623707, "end_pos": 60616031, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000043695.5", "url": "https://www.ensembl.org/id/ENSBTAT00000043695.5" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000041248.3", "url": "https://www.ensembl.org/id/ENSBTAP00000041248.3" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [], "orthologs": [], "go_annotation": { "categories": [ { "name": "Biological Process", "total": 3, "go_terms": [ { "name": "DNA-templated transcription", "id": "GO:0006351", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006351", "evidence": [ { "database": "UniProtKB", "id": "F6RZU2", "url": "https://www.uniprot.org/uniprotkb/F6RZU2" } ], "pmid": "" }, { "name": "positive regulation of DNA-templated transcription", "id": "GO:0045893", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0045893", "evidence": [ { "database": "UniProtKB", "id": "F6RZU2", "url": "https://www.uniprot.org/uniprotkb/F6RZU2" } ], "pmid": "" }, { "name": "regulation of transcription by RNA polymerase II", "id": "GO:0006357", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006357", "evidence": [ { "database": "UniProtKB", "id": "F6RZU2", "url": "https://www.uniprot.org/uniprotkb/F6RZU2" } ], "pmid": "" } ] }, { "name": "Molecular Function", "total": 5, "go_terms": [ { "name": "zinc ion binding", "id": "GO:0008270", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008270", "evidence": [ { "database": "UniProtKB", "id": "F6RZU2", "url": "https://www.uniprot.org/uniprotkb/F6RZU2" } ], "pmid": "" }, { "name": "transcription cis-regulatory region binding", "id": "GO:0000976", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000976", "evidence": [ { "database": "UniProtKB", "id": "F6RZU2", "url": "https://www.uniprot.org/uniprotkb/F6RZU2" } ], "pmid": "" }, { "name": "RNA polymerase II cis-regulatory region sequence-specific DNA binding", "id": "GO:0000978", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000978", "evidence": [ { "database": "UniProtKB", "id": "F6RZU2", "url": "https://www.uniprot.org/uniprotkb/F6RZU2" } ], "pmid": "" }, { "name": "DNA-binding transcription factor activity, RNA polymerase II-specific", "id": "GO:0000981", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000981", "evidence": [ { "database": "UniProtKB", "id": "F6RZU2", "url": "https://www.uniprot.org/uniprotkb/F6RZU2" } ], "pmid": "" }, { "name": "DNA-binding transcription factor activity", "id": "GO:0003700", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003700", "evidence": [ { "database": "UniProtKB", "id": "F6RZU2", "url": "https://www.uniprot.org/uniprotkb/F6RZU2" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 2, "go_terms": [ { "name": "nucleus", "id": "GO:0005634", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005634", "evidence": [ { "database": "UniProtKB", "id": "F6RZU2", "url": "https://www.uniprot.org/uniprotkb/F6RZU2" } ], "pmid": "" }, { "name": "nucleoplasm", "id": "GO:0005654", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005654", "evidence": [ { "database": "UniProtKB", "id": "F6RZU2", "url": "https://www.uniprot.org/uniprotkb/F6RZU2" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "F6RZU2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F6RZU2" }, { "id": "PS50157", "database": "PROSITE", "url": "https://prosite.expasy.org/PS50157" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "C2H2-type", "eco_id": "ECO_0000259", "start_pos": 310, "end_pos": 339, "start_aa": "His", "end_aa": "Pro", "glycosite_overlap": [] } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ], "tool_support": { "graph_view": "yes" } }, { "uniprot_canonical_ac": "G3MYD5-1", "uniprot_ac": "G3MYD5", "uniprot_id": "G3MYD5_BOVIN", "mass": { "chemical_mass": 71781.0, "monoisotopic_mass": 71781.0 }, "refseq": { "ac": "NP_001039649", "name": "influenza virus NS1A-binding protein", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001039649" }, "gene_names": [ { "name": "IVNS1ABP", "type": "recommended", "evidence": [ { "id": "G3MYD5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3MYD5" } ] }, { "name": "IVNS1ABP", "type": "synonym", "evidence": [ { "id": "NP_001039649", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001039649" } ] } ], "protein_names": [ { "name": "Influenza virus NS1A binding protein", "type": "synonym", "evidence": [ { "id": "G3MYD5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3MYD5/entry#names_and_taxonomy" } ] }, { "name": "influenza virus NS1A-binding protein", "type": "synonym", "evidence": [ { "id": "NP_001039649", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001039649" } ] } ], "function": [], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Bos taurus", "taxid": 9913, "evidence": [ { "database": "UniProtKB", "id": "G3MYD5", "url": "https://www.uniprot.org/uniprotkb/G3MYD5" } ], "common_name": "Bovine", "glygen_name": "Bovine", "reference_species": "Bos taurus [9913]" } ], "gene": [ { "name": "IVNS1ABP", "url": "https://www.uniprot.org/uniprotkb/G3MYD5", "locus": { "chromosome": "16", "start_pos": 66278361, "end_pos": 66299316, "strand": "+", "evidence": [ { "database": "Ensembl Gene", "id": "ENSBTAG00000014249", "url": "https://www.ensembl.org/id/ENSBTAG00000014249" } ] } } ], "crossref": [ { "id": "G3MYD5", "url": "https://alphafold.ebi.ac.uk/entry/G3MYD5", "database": "AlphaFoldDB", "categories": [] }, { "id": "ENSBTAG00000014249", "url": "https://bgee.org/?page=gene&gene_id=ENSBTAG00000014249", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "cd18306", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd18306", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "cd18502", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd18502", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "514940", "url": "https://www.ncbi.nlm.nih.gov/gene/514940", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR000210", "url": "https://www.ebi.ac.uk/interpro/entry/IPR000210", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR006652", "url": "https://www.ebi.ac.uk/interpro/entry/IPR006652", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR011333", "url": "https://www.ebi.ac.uk/interpro/entry/IPR011333", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR011705", "url": "https://www.ebi.ac.uk/interpro/entry/IPR011705", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR015915", "url": "https://www.ebi.ac.uk/interpro/entry/IPR015915", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR017096", "url": "https://www.ebi.ac.uk/interpro/entry/IPR017096", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR050457", "url": "https://www.ebi.ac.uk/interpro/entry/IPR050457", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "bta:514940", "url": "https://www.genome.jp/dbget-bin/www_bget?bta:514940", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "TEIVQDY", "url": "https://omabrowser.org/oma/group/TEIVQDY/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "A0A3Q1M681", "url": "https://www.orthodb.org/?gene=A0A3Q1M681", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A3Q1MD13", "url": "https://www.orthodb.org/?gene=A0A3Q1MD13", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "G3MYD5", "url": "https://www.orthodb.org/?gene=G3MYD5", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR24412", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR24412", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR24412:SF396", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR24412:SF396", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR46105", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR46105", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR46105:SF5", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR46105:SF5", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00651", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00651", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF01344", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF01344", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF07707", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF07707", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF24681", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF24681", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "NP_001039649", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001039649", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A3Q1M681", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1M681", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A3Q1M681-1", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1M681-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A3Q1MD13", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1MD13", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A3Q1MD13-1", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1MD13-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "G3MYD5", "url": "https://www.uniprot.org/uniprotkb/G3MYD5", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "G3MYD5-1", "url": "https://www.uniprot.org/uniprotkb/G3MYD5-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MIPNGYLMFEDENFIESSVAKLNALRKSGQFCDVRLQVCGHEMLAHRAVLACCSPYLFEIFNSDSDPHRVSHVKFDDLNPEAVEVLLNYAYTAQLKADKELVKDVYSAAKKLKMDRVKQVCGDYLLSRMDVTSCISYRNFASCMGDSRLLNKVDAYIQEHLLQISEEEEFLKLPRLKLEVMLEDTVCLPSNGKLYTKVINWVQRSIWENGDSLEELMEEVQTLYYSADHKLLDGNLLDGQAEVFGSDDDHIQFVQKKPPRENGHKQISSSSIGCLSSPNATIQSPKHEWKIVASEKTSNNTYLCLAVLDGIFCVIFLHGRNSPQSSPTSTPKLIKSLSFEMHPDELIEKPMSPMQYARSGLGTAEMNGKLIAAGGYNREECLRTVECYDPHTDHWSFLAPMRTPRARFQMAVLMGQLYVVGGSNGHSDDLSCGEMYDPNMDDWTPVPELRTNRCNAGVCALNGKLYIVGGSDPYGQKGLKNCDVFDPVTKSWTSCAPLNIRRHQSAVCELGGYLYIIGGAESWNCLNTVERYNPENNTWTLIASMNVARRGAGVAVLDGKLFVGGGFDGSHAISCVEMYDPTRNEWKMMGNMTSPRSNAGITTVGNTIFAVGGFDGNEFLNTVEVYNLESNEWSPYTKIFQF", "length": 642, "header": "tr|G3MYD5-1|G3MYD5_BOVIN Isoform 1 of Influenza virus NS1A binding protein OS=Bos taurus OX=9913 GN=IVNS1ABP PE=3 SV=1 CANONICAL=G3MYD5-1" }, "isoforms": [ { "isoform_ac": "A0A3Q1M681-1", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1M681/entry", "sequence": { "sequence": "MIPNGYLMFEDENFIESSVAKLNALRKSGQFCDVRLQVCGHEMLAHRAVLACCSPYLFEIFNSDSDPHRVSHVKFDDLNPEAVEVLLNYAYTAQLKADKELVKDVYSAAKKLKMDRVKQHLASYLHSTSFPL", "length": 132, "header": "tr|A0A3Q1M681-1|G3MYD5_BOVIN Computationally mapped isoform of Influenza virus NS1A binding protein OS=Bos taurus OX=9913 GN=IVNS1ABP PE=3 SV=2 CANONICAL=G3MYD5-1" }, "locus": { "chromosome": "16", "start_pos": 66291113, "end_pos": 66290010, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000071249.2", "url": "https://www.ensembl.org/id/ENSBTAT00000071249.2" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000069222.2", "url": "https://www.ensembl.org/id/ENSBTAP00000069222.2" } ] } }, { "isoform_ac": "A0A3Q1MD13-1", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1MD13/entry", "sequence": { "sequence": "MIPNGYLMFEDENFIESSVAKLNALRKSGQFCDVRLQVCGHEMLAHRAVLACCSPYLFEIFNSDSDPHRVSHVKFDDLNPEAVEVLLNYAYTAQLKADKELVKDVYSAAKKLKMDRVKQLEVMLEDTVCLPSNGKLYTKVINWVQRSIWENGDSLEELMEEVQTLYYSADHKLLDGNLLDGQAEVFGSDDDHIQFVQKKPPRENGHKQISSSSIGCLSSPNATIQSPKHEWKIVASEKTSNNTYLCLAVLDGIFCVIFLHGRNSPQSSPTSTPKLIKSLSFEMHPDELIEKPMSPMQYARSGLGTAEMNGKLIAAGGYNREECLRTVECYDPHTDHWSFLAPMRTPRARFQMAVLMGQLYVVGGSNGHSDDLSCGEMYDPNMDDWTPVPELRTNRCNAGVCALNGKLYIVGGSDPYGQKGLKNCDVFDPVTKSWTSCAPLNIRRHQSAVCELGGYLYIIGGAESWNCLNTVERYNPENNTWTLIASMNVARRGAGVAVLDGKLFVGGGFDGSHAISCVEMYDPTRNEWKMMGNMTSPRSNAGITTVGNTIFAVGGFDGNEFLNTVEVYNLESNEWSPYTKIFQF", "length": 584, "header": "tr|A0A3Q1MD13-1|G3MYD5_BOVIN Computationally mapped isoform of Influenza virus NS1A binding protein OS=Bos taurus OX=9913 GN=IVNS1ABP PE=3 SV=1 CANONICAL=G3MYD5-1" }, "locus": { "chromosome": "16", "start_pos": 66291113, "end_pos": 66280041, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000086665.2", "url": "https://www.ensembl.org/id/ENSBTAT00000086665.2" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000068786.1", "url": "https://www.ensembl.org/id/ENSBTAP00000068786.1" } ] } }, { "isoform_ac": "G3MYD5-1", "url": "https://www.uniprot.org/uniprotkb/G3MYD5/entry", "sequence": { "sequence": "MIPNGYLMFEDENFIESSVAKLNALRKSGQFCDVRLQVCGHEMLAHRAVLACCSPYLFEIFNSDSDPHRVSHVKFDDLNPEAVEVLLNYAYTAQLKADKELVKDVYSAAKKLKMDRVKQVCGDYLLSRMDVTSCISYRNFASCMGDSRLLNKVDAYIQEHLLQISEEEEFLKLPRLKLEVMLEDTVCLPSNGKLYTKVINWVQRSIWENGDSLEELMEEVQTLYYSADHKLLDGNLLDGQAEVFGSDDDHIQFVQKKPPRENGHKQISSSSIGCLSSPNATIQSPKHEWKIVASEKTSNNTYLCLAVLDGIFCVIFLHGRNSPQSSPTSTPKLIKSLSFEMHPDELIEKPMSPMQYARSGLGTAEMNGKLIAAGGYNREECLRTVECYDPHTDHWSFLAPMRTPRARFQMAVLMGQLYVVGGSNGHSDDLSCGEMYDPNMDDWTPVPELRTNRCNAGVCALNGKLYIVGGSDPYGQKGLKNCDVFDPVTKSWTSCAPLNIRRHQSAVCELGGYLYIIGGAESWNCLNTVERYNPENNTWTLIASMNVARRGAGVAVLDGKLFVGGGFDGSHAISCVEMYDPTRNEWKMMGNMTSPRSNAGITTVGNTIFAVGGFDGNEFLNTVEVYNLESNEWSPYTKIFQF", "length": 642, "header": "tr|G3MYD5-1|G3MYD5_BOVIN Isoform 1 of Influenza virus NS1A binding protein OS=Bos taurus OX=9913 GN=IVNS1ABP PE=3 SV=1 CANONICAL=G3MYD5-1" }, "locus": { "chromosome": "16", "start_pos": 66291113, "end_pos": 66280041, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000077993.1", "url": "https://www.ensembl.org/id/ENSBTAT00000077993.1" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000062856.1", "url": "https://www.ensembl.org/id/ENSBTAP00000062856.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [ { "id": "bta:514940", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?bta:514940", "resource": "KEGG Pathway" } ], "orthologs": [ { "uniprot_canonical_ac": "A0A0G2QC03-1", "protein_name": "Influenza virus NS1A binding protein", "gene_name": "Ivns1abp", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MIPNGYLMFEDENFIESSVAKLNALRKSGQFCDVRLQVCGHEMLAHRAVLACCSPYLFEIFNSDSDPHGVSHVKLDDLNPEAVEVLLNYAYTAQLKADKELVKDVYSAAKKLKMDRVKQVCGDYLLSRMDVTSCISYRNFASCMGDSRLLNKVDAYIQEHLLQISEEEEFLKLPRLKLEVMLEDNVCLPSNGKLYTKVINWVQRSIWENGDSLEELMEEVQTLYYSADHKLLDGNPLDGQAEVFGSDDDHIQFVQKKPPRENGHKQISGSSTGCLSSPNASVQSPKHEWKIVASEKTSNNTYLCLAVLDGTFCVIFLHGRNSPQSSPTSTPKLSKSLSFEMQPDELLEKPMSPMQYARSGLGTAEMNGKLIAAGGYNREECLRTVECYDPHTDHWSFLAPMRTPRARFQMAVLMGQLYVVGGSNGHSDDLSCGEMYDPSIDDWTPVPELRTNRCNAGVCALNGKLYIVGGSDPYGQKGLKNCDVFDPVTKSWTSCAPLNIRRHQSAVCELGGYLYIIGGAESWNCLNTVERYNPENNTWTLIAPMNVARRGAGVAVLDGKLFVGGGFDGSHAISCVEMYDPTRNEWKMMGNMTSPRSNAGITTVGNTIYAVGGFDGNEFLNTVEVYNLESNEWSPYTKIFQF", "length": 642 }, "evidence": [ { "id": "G3MYD5", "url": "https://omabrowser.org/oma/group/G3MYD5/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "Q5RG82-1", "protein_name": "Influenza virus NS1A-binding protein homolog A", "gene_name": "ivns1abpa", "tax_id": 7955, "organism": "Danio rerio", "sequence": { "sequence": "MIPNGYLIFEDESFLDSTVAKMNALRKNGQFCDVRLQVCGHELMAHRAVLACCSPYLFEIFNSDLEPHGISHVKFEDLDPEAVEILLNYAYTAQLKADKELVKEVYSAAKRLKMDRVKQICGDYLLSKMDSQSAISYRNFASCMGDGRLLGKIDSYIQEHLLEVSEQEDFLKLPRLKLEVMLEDNLTLPSNGKLYSKVIGWVQRSLWENGEPLERLMEEVQTLYYSADHKLLDGSLLDGQAEVFGTEDDHIQFVQKKPPRENVHRQLSTSSSGSLSPGSTKHPCKQEWKYIASEKTTNNTYLCLAVLNGMLCVIFLHGRSSPQASPSATPCLTKSLSFEGQPLEEEPDKLLSPMHYARSGLGIASLNDQLIAAGGYNREECLRTVECYNIKTNSWTFIAPMRTPRARFQMAVLMGQLYVMGGSNGHSDELSCGETYNPNADEWTQVPELRTNRCNAGVCSLNNKLYVVGGSDPCGQKGLKNCDVFDPISKAWTNCAPLNIRRHQAAVCELDGFMYVIGGAESWNCLNSVERYNPENNTWTLIASMNIARRGAGVAVYEGKLFVVGGFDGSHALRCVEMYDPVRNEWRMLGSMNSPRSNAGAAVLNDVIYAIGGFDGNDFLNSVEAYNPKTEEWSTCADAFTDS", "length": 643 }, "evidence": [ { "id": "G3MYD5", "url": "https://omabrowser.org/oma/group/G3MYD5/", "database": "OMA" } ], "glygen_name": "Zebrafish", "common_name": "Zebrafish" }, { "uniprot_canonical_ac": "Q920Q8-1", "protein_name": "Influenza virus NS1A-binding protein homolog", "gene_name": "Ivns1abp", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MIPNGYLMFEDENFIESSVAKLNALRKSGQFCDVRLQVCGHEMLAHRAVLACCSPYLFEIFNSDSDPHGVSHVKLDDLNPEAVEVLLNYAYTAQLKADKELVKDVYSAAKKLKMDRVKQVCGDYLLSRMDVTSCISYRNFASCMGDSRLLNKVDAYIQEHLLQISEEEEFLKLPRLKLEVMLEDNVCLPSNGKLYTKVINWVQRSIWENGDSLEELMEEVQTLYYSADHKLLDGNPLDGQAEVFGSDDDHIQFVQKKPPRENGHKQISGSSTGCLSSPNASMQSPKHEWKIVASEKTSNNTYLCLAVLDSTFCVIFLHGRNSPQSSPTSTPKLSKSLSFEMQPDELLEKPMSPMQYARSGLGTAEMNGKLIAAGGYNREECLRTVECYDPHTDHWSFLAPMRTPRARFQMAVLMGQLYVVGGSNGHSDDLSCGEMYDPNIDDWTPVPELRTNRCNAGVCALNGKLYIVGGSDPYGQKGLKNCDVFDPVTKSWTSCAPLNIRRHQSAVCELGGYLYIIGGAESWNCLNTVERYNPENNTWTLIAPMNVARRGAGVAVLDGKLFVGGGFDGSHAISCVEMYDPTRNEWKMMGNMTSPRSNAGITTVGNTIYAVGGFDGNEFLNTVEVYNPQSNEWSPYTKIFQF", "length": 642 }, "evidence": [ { "id": "G3MYD5", "url": "https://omabrowser.org/oma/group/G3MYD5/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q9Y6Y0-1", "protein_name": "Influenza virus NS1A-binding protein", "gene_name": "IVNS1ABP", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MIPNGYLMFEDENFIESSVAKLNALRKSGQFCDVRLQVCGHEMLAHRAVLACCSPYLFEIFNSDSDPHGISHVKFDDLNPEAVEVLLNYAYTAQLKADKELVKDVYSAAKKLKMDRVKQVCGDYLLSRMDVTSCISYRNFASCMGDSRLLNKVDAYIQEHLLQISEEEEFLKLPRLKLEVMLEDNVCLPSNGKLYTKVINWVQRSIWENGDSLEELMEEVQTLYYSADHKLLDGNLLDGQAEVFGSDDDHIQFVQKKPPRENGHKQISSSSTGCLSSPNATVQSPKHEWKIVASEKTSNNTYLCLAVLDGIFCVIFLHGRNSPQSSPTSTPKLSKSLSFEMQQDELIEKPMSPMQYARSGLGTAEMNGKLIAAGGYNREECLRTVECYNPHTDHWSFLAPMRTPRARFQMAVLMGQLYVVGGSNGHSDDLSCGEMYDSNIDDWIPVPELRTNRCNAGVCALNGKLYIVGGSDPYGQKGLKNCDVFDPVTKLWTSCAPLNIRRHQSAVCELGGYLYIIGGAESWNCLNTVERYNPENNTWTLIAPMNVARRGAGVAVLNGKLFVCGGFDGSHAISCVEMYDPTRNEWKMMGNMTSPRSNAGIATVGNTIYAVGGFDGNEFLNTVEVYNLESNEWSPYTKIFQF", "length": 642 }, "evidence": [ { "id": "G3MYD5", "url": "https://omabrowser.org/oma/group/G3MYD5/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" } ], "go_annotation": { "categories": [ { "name": "Molecular Function", "total": 3, "go_terms": [ { "name": "DNA binding", "id": "GO:0003677", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003677", "evidence": [ { "database": "UniProtKB", "id": "G3MYD5", "url": "https://www.uniprot.org/uniprotkb/G3MYD5" } ], "pmid": "" }, { "name": "zinc ion binding", "id": "GO:0008270", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008270", "evidence": [ { "database": "UniProtKB", "id": "G3MYD5", "url": "https://www.uniprot.org/uniprotkb/G3MYD5" } ], "pmid": "" }, { "name": "ubiquitin-like ligase-substrate adaptor activity", "id": "GO:1990756", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:1990756", "evidence": [ { "database": "UniProtKB", "id": "G3MYD5", "url": "https://www.uniprot.org/uniprotkb/G3MYD5" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 5, "go_terms": [ { "name": "nucleus", "id": "GO:0005634", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005634", "evidence": [ { "database": "UniProtKB", "id": "G3MYD5", "url": "https://www.uniprot.org/uniprotkb/G3MYD5" } ], "pmid": "" }, { "name": "cytoplasm", "id": "GO:0005737", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005737", "evidence": [ { "database": "UniProtKB", "id": "G3MYD5", "url": "https://www.uniprot.org/uniprotkb/G3MYD5" } ], "pmid": "" }, { "name": "cytosol", "id": "GO:0005829", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005829", "evidence": [ { "database": "UniProtKB", "id": "G3MYD5", "url": "https://www.uniprot.org/uniprotkb/G3MYD5" } ], "pmid": "" }, { "name": "cytoskeleton", "id": "GO:0005856", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005856", "evidence": [ { "database": "UniProtKB", "id": "G3MYD5", "url": "https://www.uniprot.org/uniprotkb/G3MYD5" } ], "pmid": "" }, { "name": "Cul3-RING ubiquitin ligase complex", "id": "GO:0031463", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0031463", "evidence": [ { "database": "UniProtKB", "id": "G3MYD5", "url": "https://www.uniprot.org/uniprotkb/G3MYD5" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 6, "go_terms": [ { "name": "DNA-templated transcription", "id": "GO:0006351", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006351", "evidence": [ { "database": "UniProtKB", "id": "G3MYD5", "url": "https://www.uniprot.org/uniprotkb/G3MYD5" } ], "pmid": "" }, { "name": "mRNA processing", "id": "GO:0006397", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006397", "evidence": [ { "database": "UniProtKB", "id": "G3MYD5", "url": "https://www.uniprot.org/uniprotkb/G3MYD5" } ], "pmid": "" }, { "name": "response to virus", "id": "GO:0009615", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0009615", "evidence": [ { "database": "UniProtKB", "id": "G3MYD5", "url": "https://www.uniprot.org/uniprotkb/G3MYD5" } ], "pmid": "" }, { "name": "proteasome-mediated ubiquitin-dependent protein catabolic process", "id": "GO:0043161", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0043161", "evidence": [ { "database": "UniProtKB", "id": "G3MYD5", "url": "https://www.uniprot.org/uniprotkb/G3MYD5" } ], "pmid": "" }, { "name": "RNA splicing", "id": "GO:0008380", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008380", "evidence": [ { "database": "UniProtKB", "id": "G3MYD5", "url": "https://www.uniprot.org/uniprotkb/G3MYD5" } ], "pmid": "" }, { "name": "negative regulation of protein ubiquitination", "id": "GO:0031397", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0031397", "evidence": [ { "database": "UniProtKB", "id": "G3MYD5", "url": "https://www.uniprot.org/uniprotkb/G3MYD5" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 279, "end_pos": 281, "annotation": "n_glycosylation_sequon" }, { "start_pos": 299, "end_pos": 301, "annotation": "n_glycosylation_sequon" }, { "start_pos": 536, "end_pos": 538, "annotation": "n_glycosylation_sequon" }, { "start_pos": 591, "end_pos": 593, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [ { "pdb_id": "AF-G3MYD5-F1", "pdb_chain": "global", "start_pos": 1, "end_pos": 642, "overlap": "1.0", "method": "AlphaFold", "type": "alphafold", "resolution": -1.0, "url": "https://data.glygen.org/ln2downloads/pdb/current/AF-G3MYD5-F1.pdb", "url_external": "https://alphafold.ebi.ac.uk/entry/G3MYD5" } ], "lectin_list": [], "domain_list": [], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" }, { "name": "homologset.oma", "label": "OMA Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 279, "end_pos": 281 }, { "start_pos": 299, "end_pos": 301 }, { "start_pos": 536, "end_pos": 538 }, { "start_pos": 591, "end_pos": 593 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ], "tool_support": { "graph_view": "yes" } }, { "uniprot_canonical_ac": "G3MY73-1", "uniprot_ac": "G3MY73", "uniprot_id": "G3MY73_BOVIN", "mass": { "chemical_mass": 86002.0, "monoisotopic_mass": 86002.0 }, "refseq": { "ac": "XP_059748674", "name": "heat shock 70 kDa protein 14 isoform X1", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_059748674" }, "gene_names": [ { "name": "HSPA14", "type": "recommended", "evidence": [ { "id": "G3MY73", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3MY73" } ] }, { "name": "HSPA14", "type": "synonym", "evidence": [ { "id": "XP_059748674", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_059748674" } ] } ], "protein_names": [ { "name": "Heat shock 70 kDa protein 14", "type": "recommended", "evidence": [ { "id": "G3MY73", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3MY73/entry#names_and_taxonomy" } ] }, { "name": "heat shock 70 kDa protein 14 isoform X1", "type": "synonym", "evidence": [ { "id": "XP_059748674", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_059748674" } ] } ], "function": [ { "annotation": "Component of the ribosome-associated complex (RAC), a complex involved in folding or maintaining nascent polypeptides in a folding-competent state. In the RAC complex, binds to the nascent polypeptide chain, while DNAJC2 stimulates its ATPase activity.", "evidence": [ { "database": "UniProtKB", "id": "A0AAA9SLV9", "url": "https://www.uniprot.org/uniprotkb/A0AAA9SLV9#function" }, { "database": "UniProtKB", "id": "ARBA00024825", "url": "https://www.uniprot.org/uniprotkb/ARBA00024825#function" }, { "database": "UniProtKB", "id": "A0AAF6Z2L7", "url": "https://www.uniprot.org/uniprotkb/A0AAF6Z2L7#function" }, { "database": "UniProtKB", "id": "A0A3Q1M9A5", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1M9A5#function" }, { "database": "UniProtKB", "id": "A0AAA9S6E9", "url": "https://www.uniprot.org/uniprotkb/A0AAA9S6E9#function" }, { "database": "UniProtKB", "id": "G3MY73", "url": "https://www.uniprot.org/uniprotkb/G3MY73#function" }, { "database": "UniProtKB", "id": "A0ABI0P2R6", "url": "https://www.uniprot.org/uniprotkb/A0ABI0P2R6#function" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Bos taurus", "taxid": 9913, "evidence": [ { "database": "UniProtKB", "id": "G3MY73", "url": "https://www.uniprot.org/uniprotkb/G3MY73" } ], "common_name": "Bovine", "glygen_name": "Bovine", "reference_species": "Bos taurus [9913]" } ], "gene": [ { "name": "HSPA14", "url": "https://www.uniprot.org/uniprotkb/G3MY73", "locus": { "chromosome": "13", "start_pos": 29517243, "end_pos": 29492741, "strand": "-", "evidence": [ { "database": "Ensembl Gene", "id": "ENSBTAG00000016451", "url": "https://www.ensembl.org/id/ENSBTAG00000016451" } ] } } ], "crossref": [ { "id": "G3MY73", "url": "https://alphafold.ebi.ac.uk/entry/G3MY73", "database": "AlphaFoldDB", "categories": [] }, { "id": "ENSBTAG00000016451", "url": "https://bgee.org/?page=gene&gene_id=ENSBTAG00000016451", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "cd10238", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd10238", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "534751", "url": "https://www.ncbi.nlm.nih.gov/gene/534751", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR013126", "url": "https://www.ebi.ac.uk/interpro/entry/IPR013126", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR018181", "url": "https://www.ebi.ac.uk/interpro/entry/IPR018181", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR029047", "url": "https://www.ebi.ac.uk/interpro/entry/IPR029047", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR042049", "url": "https://www.ebi.ac.uk/interpro/entry/IPR042049", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR043129", "url": "https://www.ebi.ac.uk/interpro/entry/IPR043129", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR044822", "url": "https://www.ebi.ac.uk/interpro/entry/IPR044822", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "A0A3Q1M9A5", "url": "https://www.orthodb.org/?gene=A0A3Q1M9A5", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "G3MY73", "url": "https://www.orthodb.org/?gene=G3MY73", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR19375", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR19375", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR47595", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR47595", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR47595:SF2", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR47595:SF2", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00012", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00012", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF13837", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF13837", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "XP_059748674", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_059748674", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A3Q1M9A5", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1M9A5", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A3Q1M9A5-1", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1M9A5-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0AAA9S6E9", "url": "https://www.uniprot.org/uniprotkb/A0AAA9S6E9", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0AAA9S6E9-1", "url": "https://www.uniprot.org/uniprotkb/A0AAA9S6E9-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0AAA9SLV9", "url": "https://www.uniprot.org/uniprotkb/A0AAA9SLV9", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0AAA9SLV9-1", "url": "https://www.uniprot.org/uniprotkb/A0AAA9SLV9-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0AAF6Z2L7", "url": "https://www.uniprot.org/uniprotkb/A0AAF6Z2L7", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0AAF6Z2L7-1", "url": "https://www.uniprot.org/uniprotkb/A0AAF6Z2L7-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0ABI0P2R6", "url": "https://www.uniprot.org/uniprotkb/A0ABI0P2R6", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0ABI0P2R6-1", "url": "https://www.uniprot.org/uniprotkb/A0ABI0P2R6-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "G3MY73", "url": "https://www.uniprot.org/uniprotkb/G3MY73", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "G3MY73-1", "url": "https://www.uniprot.org/uniprotkb/G3MY73-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MATSNSSAGIRWSRQETRTLLSILGEAEYIQRLQTVHHNADVYQAVSKRMQQEGFRRTERQCRSKFKVLKALYLKAYVAHATSMGDPPHCPFYDTLDQLLRNQIVTDADNLMEDAAWAKHSDLNLAAPDTPGEEGTSILGAKRTQAAEHQPILKTVKESDDCQLRVSDQMPETSDLEDSWDESSGAGCSQGTPSYSSSHHLFRGAAAPCQSIPMTRLAVSGEPSPCSSSSRNIHGVASAQQPPASSSRAPFVSGGDRPLTSEPPPRWARRRRRSVARTIAAELAENRRLARELSKREQEKLDRLIAIGEEASAQQDTANELRRDAVVAVRRLATAVEEATGAFQLGLEKLLQSSDDPQSRKYITESKCLVIEKNGKLLYEIDTGEEKKFVSPEDVARLIFSKMKETAHSVLGSDANDVVITVPFDFGEKQKSALGEAARAAGFNVLRLIHEPSAALLAYGIGQDSPTGKSNILVFKLGGTSLSISVMEVNSGIYRVLSTNTDNNIGGTHFTETLAQYLASEFQRSFRHDVRGNARAMMKLMNGADTAKHSLSTLGSANCFLDSLYEGQDFDCNVSRARFELLCSPLFNKCIEAIREVLEQSGFTADDINKVVLCGGSSRIPRLQQMIRDLFPAVELLNSIPPDEVIPIGAAIEAGILIGKESLSVEDALQIECSAKDILVKGVDESGANSFKVLFPSGTPLPARRQHTLQAPGSISSVCLELYESEGKNSAKVENKFAQVVLQDLDKKENGLRDILAVLTMKRDGSLHVTCTDQETGKCEAITIEVAS", "length": 788, "header": "tr|G3MY73-1|G3MY73_BOVIN Isoform 1 of Heat shock 70 kDa protein 14 OS=Bos taurus OX=9913 GN=HSPA14 PE=3 SV=2 CANONICAL=G3MY73-1" }, "isoforms": [ { "isoform_ac": "A0A3Q1M9A5-1", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1M9A5/entry", "sequence": { "sequence": "MRSSDLASQQLAQRGKKRLAPGDRLEHTEIPHTFSSDDPQSRKYITESKCLVIEKNGKLLYEIDTGEEKKFVSPEDVARLIFSKMKETAHSVLGSDANDVVITVPFDFGEKQKSALGEAARAAGFNVLRLIHEPSAALLAYGIGQDSPTGKSNILVFKLGGTSLSISVMEVNSGIYRVLSTNTDNNIGGTHFTETLAQYLASEFQRSFRHDVRGNARAMMKLMNGADTAKHSLSTLGSANCFLDSLYEGQDFDCNVSRARFELLCSPLFNKCIEAIREVLEQSGFTADDINKVVLCGGSSRIPRLQQMIRDLFPAVELLNSIPPDEVIPIGAAIEAGILIGKESLSVEDALQIECSAKDILVKGVDESGANSFKVLFPSGTPLPARRQHTLQAPGSISSVCLELYESEGKNSAKVENKFAQVVLQDLDKKENGLRDILAVLTMKRDGSLHVTCTDQETGKCEAITIEVAS", "length": 470, "header": "tr|A0A3Q1M9A5-1|G3MY73_BOVIN Computationally mapped isoform of Heat shock 70 kDa protein 14 OS=Bos taurus OX=9913 GN=HSPA14 PE=3 SV=2 CANONICAL=G3MY73-1" }, "locus": { "chromosome": "13", "start_pos": 29517148, "end_pos": 29496211, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000085544.3", "url": "https://www.ensembl.org/id/ENSBTAT00000085544.3" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000067131.2", "url": "https://www.ensembl.org/id/ENSBTAP00000067131.2" } ] } }, { "isoform_ac": "A0AAA9S6E9-1", "url": "https://www.uniprot.org/uniprotkb/A0AAA9S6E9/entry", "sequence": { "sequence": "MKLGQESDFYPCSRQKYLSSSLSSLQGSLPSLVEKTWDQVLTLPLISFSDDPQSRKYITESKCLVIEKNGKLLYEIDTGEEKKFVSPEDVARLIFSKMKETAHSVLGSDANDVVITVPFDFGEKQKSALGEAARAAGFNVLRLIHEPSAALLAYGIGQDSPTGKSNILVFKLGGTSLSISVMEVNSGIYRVLSTNTDNNIGGTHFTETLAQYLASEFQRSFRHDVRGNARAMMKLMNGADTAKHSLSTLGSANCFLDSLYEGQDFDCNVSRARFELLCSPLFNKCIEAIREVLEQSGFTADDINKVVLCGGSSRIPRLQQMIRDLFPAVELLNSIPPDEVIPIGAAIEAGILIGKESLSVEDALQIECSAKDILVKGVDESGANSFKVLFPSGTPLPARRQHTLQAPGSISSVCLELYESEGKNSAKVENKFAQVVLQDLDKKENGLRDILAVLTMKRDGSLHVTCTDQETGKCEAITIEVAS", "length": 483, "header": "tr|A0AAA9S6E9-1|G3MY73_BOVIN Computationally mapped isoform of Heat shock 70 kDa protein 14 OS=Bos taurus OX=9913 GN=HSPA14 PE=3 SV=1 CANONICAL=G3MY73-1" }, "locus": { "chromosome": "13", "start_pos": 29517148, "end_pos": 29501798, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000112030.2", "url": "https://www.ensembl.org/id/ENSBTAT00000112030.2" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000081563.1", "url": "https://www.ensembl.org/id/ENSBTAP00000081563.1" } ] } }, { "isoform_ac": "A0AAA9SLV9-1", "url": "https://www.uniprot.org/uniprotkb/A0AAA9SLV9/entry", "sequence": { "sequence": "MPGGGPERLVPGGFWTFAKKEQGGGDLELDLLIPRSVGSQLMDGRADVVANDAGDRVTPAIVAYSKNEEVVGLAAKQSRIRNISNTVMKVKQILGRSSDDPQSRKYITESKCLVIEKNGKLLYEIDTGEEKKFVSPEDVARLIFSKMKETAHSVLGSDANDVVITVPFDFGEKQKSALGEAARAAGFNVLRLIHEPSAALLAYGIGQDSPTGKSNILVFKLGGTSLSISVMEVNSGIYRVLSTNTDNNIGGTHFTETLAQYLASEFQRSFRHDVRGNARAMMKLMNGADTAKHSLSTLGSANCFLDSLYEGQDFDCNVSRARFELLCSPLFNKCIEAIREVLEQSGFTADDINKVVLCGGSSRIPRLQQMIRDLFPAVELLNSIPPDEVIPIGAAIEAGILIGKESLSVEDALQIECSAKDILVKGVDESGANSFKVLFPSGTPLPARRQHTLQAPGSISSVCLELYESEGKNSAKVENKFAQVVLQDLDKKENGLRDILAVLTMKRDGSLHVTCTDQETGKCEAITIEVAS", "length": 532, "header": "tr|A0AAA9SLV9-1|G3MY73_BOVIN Computationally mapped isoform of Heat shock 70 kDa protein 14 OS=Bos taurus OX=9913 GN=HSPA14 PE=3 SV=1 CANONICAL=G3MY73-1" }, "locus": { "chromosome": "13", "start_pos": 29517148, "end_pos": 29493253, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000100453.2", "url": "https://www.ensembl.org/id/ENSBTAT00000100453.2" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000086259.1", "url": "https://www.ensembl.org/id/ENSBTAP00000086259.1" } ] } }, { "isoform_ac": "A0AAF6Z2L7-1", "url": "https://www.uniprot.org/uniprotkb/A0AAF6Z2L7/entry", "sequence": { "sequence": "AAADPAHPGCRRTRGHPDGRADVVANDAGDRVTPAIVAYSKNEEVVGLAAKQSRIRNISNTVMKVKQILGRSSDDPQSRKYITESKCLVIEKNGKLLYEIDTGEEKKFVSPEDVARLIFSKMKETAHSVLGSDANDVVITVPFDFGEKQKSALGEAARAAGFNVLRLIHEPSAALLAYGIGQDSPTGKSNILVFKLGGTSLSISVMEVNSGIYRVLSTNTDNNIGGTHFTETLAQYLASEFQRSFRHDVRGNARAMMKLMNGADTAKHSLSTLGSANCFLDSLYEGQDFDCNVSRARFELLCSPLFNKCIEAIREVLEQSGFTADDINKVVLCGGSSRIPRLQQMIRDLFPAVELLNSIPPDEVIPIGAAIEAGILIGKESLSVEDALQIECSAKDILVKGVDESGANSFKVLFPSGTPLPARRQHTLQAPGSISSVCLELYESEGKNSAKVENKFAQVVLQDLDKKENGLRDILAVLTMKRDGSLHVTCTDQETGKCEAITIEVAS", "length": 507, "header": "tr|A0AAF6Z2L7-1|A0AAF6Z2L7_BOVIN Computationally mapped isoform of Heat shock 70 kDa protein 14 OS=Bos taurus OX=9913 GN=HSPA14 PE=3 SV=1 CANONICAL=G3MY73-1" }, "locus": { "chromosome": "13", "start_pos": 29517148, "end_pos": 29492961, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000021872.6", "url": "https://www.ensembl.org/id/ENSBTAT00000021872.6" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000021872.4", "url": "https://www.ensembl.org/id/ENSBTAP00000021872.4" } ] } }, { "isoform_ac": "A0ABI0P2R6-1", "url": "https://www.uniprot.org/uniprotkb/A0ABI0P2R6/entry", "sequence": { "sequence": "MAAIGVHLGCTSACVAVYKDGRADVVANDAGDRVTPAIVAYSKNEEVVGLAAKQSRIRNISNTVMKVKQILGRSSDDPQSRKYITESKCLVIEKNGKLLYEIDTGEEKKFVSPEDVARLIFSKMKETAHSVLGSDANDVVITVPFDFGEKQKSALGEAARAAGFNVLRLIHEPSAALLAYGIGQDSPTGKSNILVFKLGGTSLSISVMEVNSGIYRVLSTNTDNNIGGTHFTETLAQYLASEFQRSFRHDVRGNARAMMKLMNGADTAKHSLSTLGSANCFLDSLYEGQDFDCNVSRARFELLCSPLFNKCIEAIREVLEQSGFTADDINKVVLCGGSSRIPRLQQMIRDLFPAVELLNSIPPDEVIPIGAAIEAGILIGKESLSVEDALQIECSAKDILVKGVDESGANSFKVLFPSGTPLPARRQHTLQAPGSISSVCLELYESEGKNSAKVENKFAQRRNKLFQFERGKRKRSTVVFLLLFVLSTLLDNKVVLQDLDKKENGLRDILAVLTMKRDGSLHVTCTDQETGKCEAITIEVAS", "length": 542, "header": "tr|A0ABI0P2R6-1|A0ABI0P2R6_BOVIN Computationally mapped isoform of Heat shock 70 kDa protein 14 OS=Bos taurus OX=9913 GN=HSPA14 PE=3 SV=1 CANONICAL=G3MY73-1" }, "locus": { "chromosome": "13", "start_pos": 29517148, "end_pos": 29492713, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000137996.1", "url": "https://www.ensembl.org/id/ENSBTAT00000137996.1" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000107189.1", "url": "https://www.ensembl.org/id/ENSBTAP00000107189.1" } ] } }, { "isoform_ac": "G3MY73-1", "url": "https://www.uniprot.org/uniprotkb/G3MY73/entry", "sequence": { "sequence": "MATSNSSAGIRWSRQETRTLLSILGEAEYIQRLQTVHHNADVYQAVSKRMQQEGFRRTERQCRSKFKVLKALYLKAYVAHATSMGDPPHCPFYDTLDQLLRNQIVTDADNLMEDAAWAKHSDLNLAAPDTPGEEGTSILGAKRTQAAEHQPILKTVKESDDCQLRVSDQMPETSDLEDSWDESSGAGCSQGTPSYSSSHHLFRGAAAPCQSIPMTRLAVSGEPSPCSSSSRNIHGVASAQQPPASSSRAPFVSGGDRPLTSEPPPRWARRRRRSVARTIAAELAENRRLARELSKREQEKLDRLIAIGEEASAQQDTANELRRDAVVAVRRLATAVEEATGAFQLGLEKLLQSSDDPQSRKYITESKCLVIEKNGKLLYEIDTGEEKKFVSPEDVARLIFSKMKETAHSVLGSDANDVVITVPFDFGEKQKSALGEAARAAGFNVLRLIHEPSAALLAYGIGQDSPTGKSNILVFKLGGTSLSISVMEVNSGIYRVLSTNTDNNIGGTHFTETLAQYLASEFQRSFRHDVRGNARAMMKLMNGADTAKHSLSTLGSANCFLDSLYEGQDFDCNVSRARFELLCSPLFNKCIEAIREVLEQSGFTADDINKVVLCGGSSRIPRLQQMIRDLFPAVELLNSIPPDEVIPIGAAIEAGILIGKESLSVEDALQIECSAKDILVKGVDESGANSFKVLFPSGTPLPARRQHTLQAPGSISSVCLELYESEGKNSAKVENKFAQVVLQDLDKKENGLRDILAVLTMKRDGSLHVTCTDQETGKCEAITIEVAS", "length": 788, "header": "tr|G3MY73-1|G3MY73_BOVIN Isoform 1 of Heat shock 70 kDa protein 14 OS=Bos taurus OX=9913 GN=HSPA14 PE=3 SV=2 CANONICAL=G3MY73-1" }, "locus": { "chromosome": "13", "start_pos": 29517148, "end_pos": 29496371, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000064694.4", "url": "https://www.ensembl.org/id/ENSBTAT00000064694.4" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000054501.2", "url": "https://www.ensembl.org/id/ENSBTAP00000054501.2" } ] } } ], "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "other", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 192, "start_aa": "Thr", "end_pos": 192, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr192", "evidence": [ { "id": "", "database": "GlyGen", "url": "https://data.glygen.org/" } ], "filter_code": "000000000000000010000.00000000001000.0.01000" } ], "phosphorylation": [], "glycation": [], "keywords": [ "glycoprotein", "glycoprotein_predicted" ], "publication": [], "pathway": [], "orthologs": [], "go_annotation": { "categories": [ { "name": "Molecular Function", "total": 2, "go_terms": [ { "name": "ATP binding", "id": "GO:0005524", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005524", "evidence": [ { "database": "UniProtKB", "id": "G3MY73", "url": "https://www.uniprot.org/uniprotkb/G3MY73" } ], "pmid": "" }, { "name": "ATP hydrolysis activity", "id": "GO:0016887", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016887", "evidence": [ { "database": "UniProtKB", "id": "G3MY73", "url": "https://www.uniprot.org/uniprotkb/G3MY73" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 1, "go_terms": [ { "name": "cytosol", "id": "GO:0005829", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005829", "evidence": [ { "database": "UniProtKB", "id": "G3MY73", "url": "https://www.uniprot.org/uniprotkb/G3MY73" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 573, "end_pos": 575, "annotation": "n_glycosylation_sequon" }, { "start_pos": 5, "end_pos": 7, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [ { "pdb_id": "AF-G3MY73-F1", "pdb_chain": "global", "start_pos": 1, "end_pos": 788, "overlap": "1.0", "method": "AlphaFold", "type": "alphafold", "resolution": -1.0, "url": "https://data.glygen.org/ln2downloads/pdb/current/AF-G3MY73-F1.pdb", "url_external": "https://alphafold.ebi.ac.uk/entry/G3MY73" } ], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "G3MY73", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3MY73" }, { "id": "PF13837", "database": "Pfam", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF13837" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "Myb/SANT-like DNA-binding", "eco_id": "ECO_0000259", "start_pos": 11, "end_pos": 99, "start_aa": "Arg", "end_aa": "Leu", "glycosite_overlap": [] } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [ 192 ], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 573, "end_pos": 575 }, { "start_pos": 5, "end_pos": 7 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 1 }, { "field": "total_sites", "count": 1 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 1 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "exact_sites", "count": 1 }, { "field": "exact_o_linked_sites", "count": 1 }, { "field": "fuzzy_sites", "count": 0 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_pos", "start_aa", "end_pos", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 1 }, { "field": "total_sites", "count": 1 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 1 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "exact_sites", "count": 1 }, { "field": "exact_o_linked_sites", "count": 1 }, { "field": "fuzzy_sites", "count": 0 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_pos", "start_aa", "end_pos", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ], "tool_support": { "graph_view": "yes" } }, { "uniprot_canonical_ac": "G1K130-1", "uniprot_ac": "G1K130", "uniprot_id": "G1K130_BOVIN", "mass": { "chemical_mass": 103575.0, "monoisotopic_mass": 103575.0 }, "refseq": {}, "gene_names": [ { "name": "GPATCH1", "type": "recommended", "evidence": [ { "id": "G1K130", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G1K130" } ] } ], "protein_names": [ { "name": "G-patch domain containing 1", "type": "synonym", "evidence": [ { "id": "G1K130", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G1K130/entry#names_and_taxonomy" } ] } ], "function": [], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Bos taurus", "taxid": 9913, "evidence": [ { "database": "UniProtKB", "id": "G1K130", "url": "https://www.uniprot.org/uniprotkb/G1K130" } ], "common_name": "Bovine", "glygen_name": "Bovine", "reference_species": "Bos taurus [9913]" } ], "gene": [ { "name": "GPATCH1", "url": "https://www.uniprot.org/uniprotkb/G1K130", "locus": { "chromosome": "18", "start_pos": 43544122, "end_pos": 43488409, "strand": "-", "evidence": [ { "database": "Ensembl Gene", "id": "ENSBTAG00000000721", "url": "https://www.ensembl.org/id/ENSBTAG00000000721" } ] } } ], "crossref": [ { "id": "G1K130", "url": "https://alphafold.ebi.ac.uk/entry/G1K130", "database": "AlphaFoldDB", "categories": [] }, { "id": "ENSBTAG00000000721", "url": "https://bgee.org/?page=gene&gene_id=ENSBTAG00000000721", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "IPR000467", "url": "https://www.ebi.ac.uk/interpro/entry/IPR000467", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR011666", "url": "https://www.ebi.ac.uk/interpro/entry/IPR011666", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "QLWQQHA", "url": "https://omabrowser.org/oma/group/QLWQQHA/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "A0A3Q1MB05", "url": "https://www.orthodb.org/?gene=A0A3Q1MB05", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "G1K130", "url": "https://www.orthodb.org/?gene=G1K130", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR13384", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR13384", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR13384:SF19", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR13384:SF19", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF01585", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF01585", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF07713", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF07713", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF26093", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF26093", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "R-BTA-72163", "url": "https://www.reactome.org/PathwayBrowser/#R-BTA-72163", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "A0A3Q1MB05", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1MB05", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A3Q1MB05-1", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1MB05-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0ABI0NSA0", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NSA0", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0ABI0NSA0-1", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NSA0-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "G1K130", "url": "https://www.uniprot.org/uniprotkb/G1K130", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "G1K130-1", "url": "https://www.uniprot.org/uniprotkb/G1K130-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MAALDSDSDEDLVSYGTGLEPLEEGERPKKPIPLQDQTVRDEKGRYKRFHGAFSGGFSAGYFNTVGSKEGWTPSSFVSSRQNRADKSVLGPEDFMDEEDLSEFGIAPKSIVTTDDFASKTKDRIREKARQLAAATAPIPGATLLDDLITPAKLSVGFELLRKMGWKEGQGIGPRVKRRPRRQKPDPGVKIYGCALPPGGSEGSEDEDDDYLPENVTFAPKDVTPVDFTPKDNVHGLAYKGLDPHQALFGTSGEHFNLFSGGPEETGDLLGDIGVNKGRKLGISGQAFGVGALEEEDDDIYATETLSKYDTVLKDEEPGDGLYGWTAPRQYKSQKESEKDLCYVGKILDGFSLASKPLSSKKIYPPPELPRDYRPVHYFRPVVAATSENSHLLQVLSESAGKPTNDPGTRSRHQLNACKRGELLGETPIQGAPTSVLEFLSQKDKERLKEVKQATDLKAAQLRARSLAQSASGSRPQPLSPDVGHCSWHMALSGGMASTRTSNFKPFAKDPEKQKRYEEFLANMKRGQKDALERCLDPGMTEWERGRERDEFARAALLYASSHSTLSSRFTHAQEEDDSEQVEVPRDQENDVSDKQSAVKMKMFGKLTRDTFEWHPDKLLCKRFNVPDPYPDSTLVGLPRVKRDKYSVFSFLTIPETASSPVTQASSEKVAQHRASDKSRKPSRWDTSKEEKKEDSISEFLSLARSKVGPAKPEPSPLVNKEEARATESVSNKVVNKDVDSQTEGEGSRPSMDLFKAIFASSSDEKSSSSEDEQGDSEDDQEGTREADFKSSQETDLVEASSVAQASEPAPQEPAPFFPIQKMQIDEREAFGPRLPPVFCPNARQKLEAPLKEKHKKNKEKHKTKKEHRRKKEKKKKHRKHKHKGKQKNKKSEKSSSSESTDSSDSQSEEGPTDLSPQELLRRLKRLPLRRQ", "length": 931, "header": "tr|G1K130-1|G1K130_BOVIN Isoform 1 of G-patch domain containing 1 OS=Bos taurus OX=9913 GN=GPATCH1 PE=3 SV=3 CANONICAL=G1K130-1" }, "isoforms": [ { "isoform_ac": "A0A3Q1MB05-1", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1MB05/entry", "sequence": { "sequence": "MGLAWSRWKKVRDQRSRFLSRIRPSEMKKEGINDFMEPLVEVSLLVTSTLLAQKKDGHPLPSCLHDRTEQTSLFLVPKILWMKRLSVGFELLRKMGWKEGQGIGPRVKRRPRRQKPDPGVKIYGCALPPGGSEGSEDEDDDYLPENVTFAPKDVTPVDFTPKDNVHGLAYKGLDPHQALFGTSGEHFNLFSGGPEETGDLLGDIGVNKGRKLGISGQAFGVGALEEEDDDIYATETLSKYDTVLKDEEPGDGLYGWTAPRQYKSQKESEKDLCYVGKILDGFSLASKPLSSKKIYPPPELPRDYRPVHYFRPVVAATSENSHLLQVLSESAGKPTNDPGTRSRHQLNACKRGELLGETPIQGAPTSVLEFLSQKDKERLKEVKQATDLKAAQLRARSLAQSASGSRPQPLSPDVGHCSWHMALSGGMASTRTSNFKPFAKDPEKQKRYEEFLANMKRGQKDALERCLDPGMTEWERGRERDEFARAALLYASSHSTLSSRFTHAQEEDDSEQVEVPRDQENDVSDKQSAVKMKMFGKLTRDTFEWHPDKLLCKRFNVPDPYPDSTLVGLPRVKRDKYSVFSFLTIPETASSPVTQASSEKVAQHRASDKSRKPSRWDTSKEEKKEDSISEFLSLARSKVGPAKPEPSPLVNKEEARATESVSNKVVNKDVDSQTEGEGSRPSMDLFKAIFASSSDEKSSSSEDEQGDSEDDQEGTREADFKSSQETDLVEASSVAQASEPAPQEPAPFFPIQKMQIDEREAFGPRLPPVFCPNARQKLEAPLKEKHKKNKEKHKTKKEHRRKKEKKKKHRKHKHKGKQKNKKSEKSSSSESTDSSDSQSEEGPTDLSPQELLRRLKRLPLRRQ", "length": 863, "header": "tr|A0A3Q1MB05-1|G1K130_BOVIN Computationally mapped isoform of G-patch domain containing 1 OS=Bos taurus OX=9913 GN=GPATCH1 PE=3 SV=1 CANONICAL=G1K130-1" }, "locus": { "chromosome": "18", "start_pos": 43543870, "end_pos": 43488469, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000071524.3", "url": "https://www.ensembl.org/id/ENSBTAT00000071524.3" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000071226.1", "url": "https://www.ensembl.org/id/ENSBTAP00000071226.1" } ] } }, { "isoform_ac": "A0ABI0NSA0-1", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NSA0/entry", "sequence": { "sequence": "MGLAWSRWKKMRKLRHREVKMTRIAELVKGERPKKPIPLQDQTVRDEKGRYKRFHGAFSGGFSAGYFNTVGSKEGWTPSSFVSSRQNRADKSVLGPEDFMDEEDLSEFGIAPKSIVTTDDFASKTKDRIREKARQLAAATAPIPGATLLDDLITPAKLSVGFELLRKMGWKEGQGIGPRVKRRPRRQKPDPGVKIYGCALPPGGSEGSEDEDDDYLPENVTFAPKDVTPVDFTPKDNVHGLAYKGLDPHQALFGTSGEHFNLFSGGPEETGDLLGDIGVNKGRKLGISGQAFGVGALEEEDDDIYATETLSKYDTVLKDEEPGDGLYGWTAPRQYKSQKESEKDLCYVGKILDGFSLASKPLSSKKIYPPPELPRDYRPVHYFRPVVAATSENSHLLQVLSESAGKPTNDPGTRSRHQLNACKRGELLGETPIQGAPTSVLEFLSQKDKERLKEVKQATDLKAAQLRARSLAQSASGSRPQPLSPDVGHCSWHMALSGGMASTRTSNFKPFAKDPEKQKRYEEFLANMKRGQKDALERCLDPGMTEWERGRERDEFARAALLYASSHSTLSSRFTHAQEEDDSEQVEVPRDQENDVSDKQSAVKMKMFGKLTRDTFEWHPDKLLCKRFNVPDPYPDSTLVGLPRVKRDKYSVFSFLTIPETASSPVTQASSEKVAQHRASDKSRKPSRWDTSKEEKKEDSISEFLSLARSKVGPAKPEPSPLVNKEEARATESVSNKVVNKDVDSQTEGEGSRPSMDLFKAIFASSSDEKSSSSEDEQGDSEDDQEGTREADFKSSQETDLVEASSVAQASEPAPQEPAPFFPIQKMQIDEREAFGPRLPPVFCPNARQKLEAPLKEKHKKNKEKHKTKKEHRRKKEKKKKHRKHKHKGKQKNKKSEKSSSSESTDSSDSQSEEGPTDLSPQELLRRLKRLPLRRQ", "length": 936, "header": "tr|A0ABI0NSA0-1|A0ABI0NSA0_BOVIN Computationally mapped isoform of G-patch domain containing 1 OS=Bos taurus OX=9913 GN=GPATCH1 PE=3 SV=1 CANONICAL=G1K130-1" }, "locus": { "chromosome": "18", "start_pos": 43543870, "end_pos": 43488469, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000139747.1", "url": "https://www.ensembl.org/id/ENSBTAT00000139747.1" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000105714.1", "url": "https://www.ensembl.org/id/ENSBTAP00000105714.1" } ] } }, { "isoform_ac": "G1K130-1", "url": "https://www.uniprot.org/uniprotkb/G1K130/entry", "sequence": { "sequence": "MAALDSDSDEDLVSYGTGLEPLEEGERPKKPIPLQDQTVRDEKGRYKRFHGAFSGGFSAGYFNTVGSKEGWTPSSFVSSRQNRADKSVLGPEDFMDEEDLSEFGIAPKSIVTTDDFASKTKDRIREKARQLAAATAPIPGATLLDDLITPAKLSVGFELLRKMGWKEGQGIGPRVKRRPRRQKPDPGVKIYGCALPPGGSEGSEDEDDDYLPENVTFAPKDVTPVDFTPKDNVHGLAYKGLDPHQALFGTSGEHFNLFSGGPEETGDLLGDIGVNKGRKLGISGQAFGVGALEEEDDDIYATETLSKYDTVLKDEEPGDGLYGWTAPRQYKSQKESEKDLCYVGKILDGFSLASKPLSSKKIYPPPELPRDYRPVHYFRPVVAATSENSHLLQVLSESAGKPTNDPGTRSRHQLNACKRGELLGETPIQGAPTSVLEFLSQKDKERLKEVKQATDLKAAQLRARSLAQSASGSRPQPLSPDVGHCSWHMALSGGMASTRTSNFKPFAKDPEKQKRYEEFLANMKRGQKDALERCLDPGMTEWERGRERDEFARAALLYASSHSTLSSRFTHAQEEDDSEQVEVPRDQENDVSDKQSAVKMKMFGKLTRDTFEWHPDKLLCKRFNVPDPYPDSTLVGLPRVKRDKYSVFSFLTIPETASSPVTQASSEKVAQHRASDKSRKPSRWDTSKEEKKEDSISEFLSLARSKVGPAKPEPSPLVNKEEARATESVSNKVVNKDVDSQTEGEGSRPSMDLFKAIFASSSDEKSSSSEDEQGDSEDDQEGTREADFKSSQETDLVEASSVAQASEPAPQEPAPFFPIQKMQIDEREAFGPRLPPVFCPNARQKLEAPLKEKHKKNKEKHKTKKEHRRKKEKKKKHRKHKHKGKQKNKKSEKSSSSESTDSSDSQSEEGPTDLSPQELLRRLKRLPLRRQ", "length": 931, "header": "tr|G1K130-1|G1K130_BOVIN Isoform 1 of G-patch domain containing 1 OS=Bos taurus OX=9913 GN=GPATCH1 PE=3 SV=3 CANONICAL=G1K130-1" }, "locus": { "chromosome": "18", "start_pos": 43543870, "end_pos": 43488426, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000000963.7", "url": "https://www.ensembl.org/id/ENSBTAT00000000963.7" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000000963.5", "url": "https://www.ensembl.org/id/ENSBTAP00000000963.5" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [ { "id": "R-BTA-72163", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-BTA-72163", "resource": "Reactome", "description": "mRNA Splicing - Major Pathway" } ], "orthologs": [ { "uniprot_canonical_ac": "F1LU70-1", "protein_name": "G patch domain containing 1", "gene_name": "Gpatch1", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MAALDSDSEEDLISYGTGLEPLEEGERPKKPIPLQDQTVRDEKGRYKRFHGAFSGGFSAGYFNTVGSKEGWTPSTFVSSRQNRADKSALGPEDFMDEEDLSEFGIAPKAIVTTDDFASKTKDRIREKARQLAAAAAPIPGATLLDDLITPAKLSVGFELLRKMGWKEGQGVGPRVKRKARRQKADPGVKIYGCALPPGGSEGSEDEDDDYLPDNVTFAPKDVMPVDFTPKDNVHGLAYKGLDPHQALFGMPGEHLNLFGGASEGTSHLLGDVGLSKGRKLGISGQAFGVGALEEEDDDIYATETLSKYDTVLKDEEPGDGLYGWTAPKQYKNHKEPERDLRYVGKILEGFSLASKPLSSKKIYPPPELPRDYRPVHYFRPVVAATSKNAHLLQVLSESSGKAGQDMGTHSRHQLNASKRGELLGEMPVQGSATSVLEFLSQKDKERIKEVKQATDLKAAQAKARSLAQSASSSRAQASTPDPGHSSWHLALGSGTVTTRASNFKPFAKDPEKQRRYEEFLVHMKKGQKDALERCLDPNMTEWERSREREEFARAAQLYVSSNSTLSSRFTHAKEEDDSDQVEVPRDQENDLSDKQSAVKMKMFGKLTRDTFEWHPDKLLCKRFNVPDPYPGSTLVGLPRVKRDKYSVFNFLTLSEPASLPTAPVPSEKAPQQRGPDKSRKPSRWDTSKQEKKEDSISEFLSQARSKVGPSKQESSALGSKEEQASEPHPDMTVDKAVDAQPDREGSRPSMDLFKAIFASSSDEKSSSSEEEQDDSEDSQEHTEEASLKGSQEAAVGETSLIHAAEQEPGEPATPFPIQKVQIDEREEFGPRLPPVFCPNVRQKLEIPHKEKPKKSKERHRSKKEHRRKREKKKKHKKHKHKSKQKNKKSEKNSSSESTDSSDSGSDAGGSTELSPQELLRRLKCLPLRRQ", "length": 930 }, "evidence": [ { "id": "G1K130", "url": "https://omabrowser.org/oma/group/G1K130/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "G1K2G6-1", "protein_name": "G patch domain-containing protein 1", "gene_name": "gpatch1", "tax_id": 7955, "organism": "Danio rerio", "sequence": { "sequence": "MASDEDSDEDFVTYGTPLEPLEEDEPSRKPIPVHEQTVKDEKGRYKRFHGAFTGGFSAGYFNTVGSKEGWTPSTFVSSRQQKSEKHNARPEDFMDEEDFGEHGIAPREITTTDEFASERKDQIKDKARAVSSLAALIPGDPGLLEEFIAPARSSIGVELLRKMGWKDGQGVGPRLKRKPRKQNTGRVYGCSLPRNGSEESEEDDDEFAPENVTFAPKDVVPVDFTPKVDSHGLGYRGLNPLQALGGGSGSGHINLFTLQSDRTTNLFGDRASGQERRGGIAGQAFGVGAMEEEDGDIYHKDSMSNYDNVLGGEEPGDGLYGWTAPQQYTKKKNALKRVMAYSGRILDGFALASEVTEIKTVYPPPDLPRDFRPVHYFRPVIDPSTVSPIVAQALQLSRGQLSQDASQQGRHKLDSTQRRDMLGESALQGPSSVFELLESKDRERLTEIRKAAESQKPSESNLSSAVDRAVVVASAKAKAAALQALSSRFQSSSTQPQPPSETQMALNAWSGPTADASKTFKPFSKNPQKQARYDLYISKLKQGDKDAVELSLDSSMTEWERGREREEFVRAALLYKPSSSSLSSRFTHGKHEEDTDTVDVAQEQENDVDDKQAAVKMKMFGKLTRDTFEWHPDKLLCKRFNIPDPYPGSSMVGMPKVKRDKYSVFNFLTIPDGSQVNPSDPKPSSSTIPRVTAEASSKKSRWDVPVQASEPKDAVSAFLSETRSEVSATQQTEAEVKTQTDALPASATSEVKVAQSVEKQSDQKNEEEEEEEEEEVRPSMDLFKAIFASSSDEKSSSSSEDEAEEEEELAPPTSEAAQSTTTSGTVIPPIPAQFTPAPDINKAMDLKHLTVQSVPSAETTAQSTQSSLNAPAKSQGLDEEEFGPRLPPPGFVPSTHSPQMKKQKKKDKEKHKGKKHKKEKKKKKSKKHKHKGKQKKRHEESDSSSDDTDSNSEDVDRDVPTSELLQRLKNLKNKR", "length": 975 }, "evidence": [ { "id": "G1K130", "url": "https://omabrowser.org/oma/group/G1K130/", "database": "OMA" } ], "glygen_name": "Zebrafish", "common_name": "Zebrafish" }, { "uniprot_canonical_ac": "Q9BRR8-1", "protein_name": "G patch domain-containing protein 1", "gene_name": "GPATCH1", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MAARDSDSEEDLVSYGTGLEPLEEGERPKKPIPLQDQTVRDEKGRYKRFHGAFSGGFSAGYFNTVGSKEGWTPSTFVSSRQNRADKSVLGPEDFMDEEDLSEFGIAPKAIVTTDDFASKTKDRIREKARQLAAATAPIPGATLLDDLITPAKLSVGFELLRKMGWKEGQGVGPRVKRRPRRQKPDPGVKIYGCALPPGSSEGSEGEDDDYLPDNVTFAPKDVTPVDFTPKDNVHGLAYKGLDPHQALFGTSGEHFNLFSGGSERAGDLGEIGLNKGRKLGISGQAFGVGALEEEDDDIYATETLSKYDTVLKDEEPGDGLYGWTAPRQYKNQKESEKDLRYVGKILDGFSLASKPLSSKKIYPPPELPRDYRPVHYFRPMVAATSENSHLLQVLSESAGKATPDPGTHSKHQLNASKRAELLGETPIQGSATSVLEFLSQKDKERIKEMKQATDLKAAQLKARSLAQNAQSSRAQLSPAAAAGHCSWNMALGGGTATLKASNFKPFAKDPEKQKRYDEFLVHMKQGQKDALERCLDPSMTEWERGRERDEFARAALLYASSHSTLSSRFTHAKEEDDSDQVEVPRDQENDVGDKQSAVKMKMFGKLTRDTFEWHPDKLLCKRFNVPDPYPDSTLVGLPRVKRDKYSVFNFLTLPETASLPTTQASSEKVSQHRGPDKSRKPSRWDTSKHEKKEDSISEFLSLARSKAEPPKQQSSPLVNKEEEHAPELSANQTVNKDVDAQAEGEGSRPSMDLFRAIFASSSDEKSSSSEDEQGDSEDDQAGSGEANFQSSQDTDLGETSSVAHALVPAPQEPPPSFPIQKMQIDEREEFGPRLPPVFCPNARQTLEVPQKEKHKKNKDKHKAKKEHRRKKEKKKKHRKHKHKGKQKNKKPEKSSSSESSDSSDSQSDEETADVSPQELLRRLKSLPLRRQ", "length": 931 }, "evidence": [ { "id": "G1K130", "url": "https://omabrowser.org/oma/group/G1K130/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "Q9DBM1-1", "protein_name": "G patch domain-containing protein 1", "gene_name": "Gpatch1", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MAALDSDSDEDLISYGTGLEPLDEGERPKKPIPLQDQTVRDEKGRYKRFHGAFSGGFSAGYFNTVGSKEGWTPSTFVSSRQNRADKSALGPEDFMDEEDLSEFGIAPKAIVTTDDFASKTKDRIREKARQLAAAAAPIPGATLLDDLITPAKLSVGFELLRKMGWKEGQGVGPRVKRKARRQKPDPGVKIYGCALPPGGSEESEDEDDDYLPDNVTFAPKDVMPVDFTPKDNVHGLAYKGLDPHQALFGMPGEHLNLFGGASEGTSHLLGDVGLSKGRKLGISGQAFGVGALEEEDDDIYATETLSKYDTVLKDEEPGDGLYGWTAPKQYKNQKEPERDLRYVGKILEGFSLASKPLSSKKIYPPPQLPRDYRPVHYFRPVVAATAENAHVLQVLSESSGKAGQDVGTHSRHQLNASKRGELLGEMPIQGSATSVLEFLSQKDKERIKEVKQATDLKAAQAKARSLAQSASSSRAQASTPDLGHSSWHLALGGGTVTTRANNFKPFAKDPEKQRRYEEFLVHMKKGQKDALERCLDPSMTEWERSREREEFARAAQLYVSSNSTLSSRFTHAKEEEDSDQVEVPRDQENDVSDKQSAVKMKMFGKLTRDTFEWHPDKLLCKRFNVPDPYPGSTLVGLPRVKRDKYSVFNFLTLPEPAPLPTAPVPSEKAPQQRGSDKSRKPSRWDTSKQEKKEDSISEFLSQARSKVGPPKQESSALGSKEEQAPEPRPDTTVDKAVDAQTDGEGSRPSMDLFKAIFASSSDEKSSSSEEEQDDSEDSQEHTEEASLKGSQEAAAGETSVVLAAEPEPCEPATPFPIQKAQIDEREEFGPRLPPVFCPNSRQKLEIPQKEKPKKSKERHKSKKEHRRKREKKKKHKKHKHKSKQKNKKSEKNSSSESTDSSDSGSDDGGPAELSPQELLRRLKCLPLRRQ", "length": 930 }, "evidence": [ { "id": "G1K130", "url": "https://omabrowser.org/oma/group/G1K130/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q9VUA0-1", "protein_name": "G patch domain-containing protein 1 homolog", "gene_name": "", "tax_id": 7227, "organism": "Drosophila melanogaster", "sequence": { "sequence": "MDEEEHLHRFGTPLPALQKDVVPAKKPVAIEDQIVKDENGKRRFHGAFTGGFSAGFWNTVGSLEGWTPQTFKSSRGERASSKAQLKPEDFMDQEDLGEFGIAPQGIRTRDEFANEDEQKQRSDQRRRKLMQPELGVGAIPGLPVLEQLLRPVRDKVAVRILKSMGWKPGQGVGPRQTRKEKRQATARNSKEQYLMEHYGAEGLPSNKENKGEEDSNNEDEDDEDITFAPDDYEPIFYTPKENRFGMSYSGLNRDPILSKSSSSSAKPMQHINLFGEMEAQANKKQLSIRGQAFGVGAFEEEDEDIYARDDMTRYDFSLADKKPKQKKQQHVQQRHVIDGFSEDNSPAVLQRPYAIDLPRDFQPRNWLQRRSRFAPMDKERAQKLETASEYKRSGLGRHDLNPDQRAQILGEQQQEEKTAEEQPKRNPFKDHSKSLMERINARTEGFTKGGVITENGEEQQTELAKEVKEANAAIQERAALKTKDLPSAMNSSSAFKPFIADEAKQLRYEKFVSSKLTDDKEITEFLARMQPVTLSLWDREMEKKEFIQAAKIYRPLVGLMNDRFVSEANVQAEKVEQQEKPPEERKIVMERTKTMWKPTALLCKRYNIAEPFGGAMLEPEKELKAKAKISVFDYLETSVNTKANFETPSIFPKHIEKSIPEKVETPPSPPPAPQPEAEIQDKPNTKEEPSKHTFVPKTPLEQAVDESRNKPISEKVDLFKSIFEDSDEEETELSEQDKLAILQESFGLPVTSTTSAAAQNVLRNTSPPRGIFASLFSPKIKDAAKEPAPTKFGPIEGSKLKIAYKPRKERLRNDRELAMAEVAPEDIYGPKLPTAPPQKPAAPEIQAEANIDDRLQQLWQQHAPKKRKAEKWVEKKCISGSEDSDASSSNESSSSDSSDDNDKRSKLSKPKKSHKGSSSKKSKKSKLKSKKKSKKSEESKHKAKKKKKKSKH", "length": 952 }, "evidence": [ { "id": "G1K130", "url": "https://omabrowser.org/oma/group/G1K130/", "database": "OMA" } ], "glygen_name": "Fruit fly", "common_name": "Fruit fly" } ], "go_annotation": { "categories": [ { "name": "Molecular Function", "total": 2, "go_terms": [ { "name": "nucleic acid binding", "id": "GO:0003676", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003676", "evidence": [ { "database": "UniProtKB", "id": "G1K130", "url": "https://www.uniprot.org/uniprotkb/G1K130" } ], "pmid": "" }, { "name": "RNA binding", "id": "GO:0003723", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003723", "evidence": [ { "database": "UniProtKB", "id": "G1K130", "url": "https://www.uniprot.org/uniprotkb/G1K130" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 1, "go_terms": [ { "name": "nucleus", "id": "GO:0005634", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005634", "evidence": [ { "database": "UniProtKB", "id": "G1K130", "url": "https://www.uniprot.org/uniprotkb/G1K130" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 1, "go_terms": [ { "name": "mRNA processing", "id": "GO:0006397", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006397", "evidence": [ { "database": "UniProtKB", "id": "G1K130", "url": "https://www.uniprot.org/uniprotkb/G1K130" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 214, "end_pos": 216, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [ { "pdb_id": "AF-G1K130-F1", "pdb_chain": "global", "start_pos": 1, "end_pos": 931, "overlap": "1.0", "method": "AlphaFold", "type": "alphafold", "resolution": -1.0, "url": "https://data.glygen.org/ln2downloads/pdb/current/AF-G1K130-F1.pdb", "url_external": "https://alphafold.ebi.ac.uk/entry/G1K130" } ], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "G1K130", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G1K130" }, { "id": "PS50174", "database": "PROSITE", "url": "https://prosite.expasy.org/PS50174" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "G-patch", "eco_id": "ECO_0000259", "start_pos": 152, "end_pos": 172, "start_aa": "Lys", "end_aa": "Gly", "glycosite_overlap": [] } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" }, { "name": "homologset.oma", "label": "OMA Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 214, "end_pos": 216 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ], "tool_support": { "graph_view": "yes" } }, { "uniprot_canonical_ac": "G3N1L7-1", "uniprot_ac": "G3N1L7", "uniprot_id": "G3N1L7_BOVIN", "mass": { "chemical_mass": 95603.0, "monoisotopic_mass": 95603.0 }, "refseq": { "ac": "NP_001193792", "name": "follistatin-related protein 5 precursor", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001193792" }, "gene_names": [ { "name": "FSTL5", "type": "recommended", "evidence": [ { "id": "G3N1L7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3N1L7" } ] }, { "name": "FSTL5", "type": "synonym", "evidence": [ { "id": "NP_001193792", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001193792" } ] } ], "protein_names": [ { "name": "Follistatin-related protein 5", "type": "recommended", "evidence": [ { "id": "G3N1L7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3N1L7/entry#names_and_taxonomy" } ] }, { "name": "Follistatin-like protein 5", "type": "synonym", "evidence": [ { "id": "G3N1L7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3N1L7/entry#names_and_taxonomy" } ] }, { "name": "follistatin-related protein 5 precursor", "type": "synonym", "evidence": [ { "id": "NP_001193792", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001193792" } ] } ], "function": [], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Bos taurus", "taxid": 9913, "evidence": [ { "database": "UniProtKB", "id": "G3N1L7", "url": "https://www.uniprot.org/uniprotkb/G3N1L7" } ], "common_name": "Bovine", "glygen_name": "Bovine", "reference_species": "Bos taurus [9913]" } ], "gene": [ { "name": "FSTL5", "url": "https://www.uniprot.org/uniprotkb/G3N1L7", "locus": { "chromosome": "17", "start_pos": 37189264, "end_pos": 36318696, "strand": "-", "evidence": [ { "database": "Ensembl Gene", "id": "ENSBTAG00000047595", "url": "https://www.ensembl.org/id/ENSBTAG00000047595" } ] } } ], "crossref": [ { "id": "G3N1L7", "url": "https://alphafold.ebi.ac.uk/entry/G3N1L7", "database": "AlphaFoldDB", "categories": [] }, { "id": "ENSBTAG00000047595", "url": "https://bgee.org/?page=gene&gene_id=ENSBTAG00000047595", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "cd00096", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd00096", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "cd00104", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd00104", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "cd05736", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd05736", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "782831", "url": "https://www.ncbi.nlm.nih.gov/gene/782831", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR002048", "url": "https://www.ebi.ac.uk/interpro/entry/IPR002048", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR002350", "url": "https://www.ebi.ac.uk/interpro/entry/IPR002350", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR003598", "url": "https://www.ebi.ac.uk/interpro/entry/IPR003598", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR003599", "url": "https://www.ebi.ac.uk/interpro/entry/IPR003599", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR007110", "url": "https://www.ebi.ac.uk/interpro/entry/IPR007110", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR011992", "url": "https://www.ebi.ac.uk/interpro/entry/IPR011992", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR013783", "url": "https://www.ebi.ac.uk/interpro/entry/IPR013783", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR015943", "url": "https://www.ebi.ac.uk/interpro/entry/IPR015943", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR018247", "url": "https://www.ebi.ac.uk/interpro/entry/IPR018247", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR036058", "url": "https://www.ebi.ac.uk/interpro/entry/IPR036058", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR036179", "url": "https://www.ebi.ac.uk/interpro/entry/IPR036179", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR050653", "url": "https://www.ebi.ac.uk/interpro/entry/IPR050653", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "bta:782831", "url": "https://www.genome.jp/dbget-bin/www_bget?bta:782831", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "IHAGNYT", "url": "https://omabrowser.org/oma/group/IHAGNYT/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "G3N1L7", "url": "https://www.orthodb.org/?gene=G3N1L7", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR10913", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR10913", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR10913:SF44", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR10913:SF44", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF07648", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF07648", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF13927", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF13927", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "NP_001193792", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001193792", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A3Q1MCL0", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1MCL0", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A3Q1MCL0-1", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1MCL0-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "G3N1L7", "url": "https://www.uniprot.org/uniprotkb/G3N1L7", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "G3N1L7-1", "url": "https://www.uniprot.org/uniprotkb/G3N1L7-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MLKCWSAVLILGFIFLESEGRPTKEAGYGLKSYQPLIRLRHKQEKSQERSRIKGILIQDGSLGSCENKYCGLGRHCVLSRETGQAECACMDHCNRHYKPVCGSDGEFYENHCEVHRAACLKKHKITIVHNEDCFFKGDNCKAIEYSKMKSMLLDLQNQKYITQDNENPNGDDVFRKKLLVDQMFKYFDADSNGLVDINELIQVIKQEELGKDLSDCTLYDLLKYDDFNSDKHLALEEFYRTFQVIQLSLPEDQKLSVTAATVGQSTVLSCAIQGALRPPIIWKRNNIILNNLDLEDINDFGDDGSLYITKVTTTHMGNYTCYAEGYENIYQTHIFQVNVPPVIRVYPESQAREPGVTASLRCHAEGIPNPQLSWLKNGIDITPKLSKQLTLQANGSEVHISNVRYEDTGAYTCIAKNEAGVDEDISSLFVEDSARKTLANILWREEGLGIGNMFYVFYEDGIKVIQPIECEFQRHIKPSEKLLGFQDEVCPKAEGDEIQRCVWASAVNVKDKFIYVAQPTLDRVLVVDVQSQKVVQAVSTDPVPVKLHYDKSHDQVWVLSWGTMEKTSPTLQVITLASGNVPHHTIHTQPVGKQFDRVDDFFIPTTTLLITHIRFGFILHKDEAALQKIDLETMSYIKTINLKDYQCIPQSLAYTHLGGYYFIGCKPDSTGAAPPQLLVDGVTDSVIGFNSDVTGTPYVSPDGHYLVTISDVKGLVRVQYITIRGEIQEAFDIHTNLHISDLAFQPSFTEAHQYNIYGSSSTQTDVLFVELASGKVKMIKSLKEPLKAEEWPWNLKNRQIQDSGLFGQYLMTPSKDSLFILDGRLNKLNCEITEVEKGNTVIWVGEA", "length": 847, "header": "tr|G3N1L7-1|G3N1L7_BOVIN Isoform 1 of Follistatin-related protein 5 OS=Bos taurus OX=9913 GN=FSTL5 PE=4 SV=2 CANONICAL=G3N1L7-1" }, "isoforms": [ { "isoform_ac": "A0A3Q1MCL0-1", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1MCL0/entry", "sequence": { "sequence": "MLKCWSAVLILGFIFLESEGRPTKEAGYGLKSYQPLIRLRHKEKSQERSRIKGILIQDGSLGSCENKYCGLGRHCVLSRETGQAECACMDHCNRHYKPVCGSDGEFYENHCEVHRAACLKKHKITIVHNEDCFFKGDNCKAIEYSKMKSMLLDLQNQKYITQDNENPNGDDVFRKKLLVDQMFKYFDADSNGLVDINELIQVIKQEELGKDLSDCTLYDLLKYDDFNSDKHLALEEFYRTFQVIQLSLPEDQKLSVTAATVGQSTVLSCAIQGALRPPIIWKRNNIILNNLDLEDINDFGDDGSLYITKVTTTHMGNYTCYAEGYENIYQTHIFQVNVPPVIRVYPESQAREPGVTASLRCHAEGIPNPQLSWLKNGIDITPKLSKQLTLQANGSEVHISNVRYEDTGAYTCIAKNEAGVDEDISSLFVEDSARKTRLGIGNMFYVFYEDGIKVIQPIECEFQRHIKPSEKLLGFQDEVCPKAEGDEIQRCVWASAVNVKDKFIYVAQPTLDRVLVVDVQSQKVVQAVSTDPVPVKLHYDKSHDQVWVLSWGTMEKTSPTLQVITLASGNVPHHTIHTQPVGKQFDRVDDFFIPTTTLLITHIRFGFILHKDEAALQKIDLETMSYIKTINLKDYQCIPQSLAYTHLGGYYFIGCKPDSTGAAPPQLLVDGVTDSVIGFNSDVTGTPYVSPDGHYLVTISDVKGLVRVQYITIRGEIQEAFDIHTNLHISDLAFQPSFTEAHQYNIYGSSSTQTDVLFVELASGKVKMIKSLKEPLKAEEWPWNLKNRQIQDSGLFGQYLMTPSKDSLFILDGRLNKLNCEITEVEKGNTVIWVGEA", "length": 837, "header": "tr|A0A3Q1MCL0-1|G3N1L7_BOVIN Computationally mapped isoform of Follistatin-related protein 5 OS=Bos taurus OX=9913 GN=FSTL5 PE=4 SV=2 CANONICAL=G3N1L7-1" }, "locus": { "chromosome": "17", "start_pos": 37189198, "end_pos": 36318696, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000085199.2", "url": "https://www.ensembl.org/id/ENSBTAT00000085199.2" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000066515.2", "url": "https://www.ensembl.org/id/ENSBTAP00000066515.2" } ] } }, { "isoform_ac": "G3N1L7-1", "url": "https://www.uniprot.org/uniprotkb/G3N1L7/entry", "sequence": { "sequence": "MLKCWSAVLILGFIFLESEGRPTKEAGYGLKSYQPLIRLRHKQEKSQERSRIKGILIQDGSLGSCENKYCGLGRHCVLSRETGQAECACMDHCNRHYKPVCGSDGEFYENHCEVHRAACLKKHKITIVHNEDCFFKGDNCKAIEYSKMKSMLLDLQNQKYITQDNENPNGDDVFRKKLLVDQMFKYFDADSNGLVDINELIQVIKQEELGKDLSDCTLYDLLKYDDFNSDKHLALEEFYRTFQVIQLSLPEDQKLSVTAATVGQSTVLSCAIQGALRPPIIWKRNNIILNNLDLEDINDFGDDGSLYITKVTTTHMGNYTCYAEGYENIYQTHIFQVNVPPVIRVYPESQAREPGVTASLRCHAEGIPNPQLSWLKNGIDITPKLSKQLTLQANGSEVHISNVRYEDTGAYTCIAKNEAGVDEDISSLFVEDSARKTLANILWREEGLGIGNMFYVFYEDGIKVIQPIECEFQRHIKPSEKLLGFQDEVCPKAEGDEIQRCVWASAVNVKDKFIYVAQPTLDRVLVVDVQSQKVVQAVSTDPVPVKLHYDKSHDQVWVLSWGTMEKTSPTLQVITLASGNVPHHTIHTQPVGKQFDRVDDFFIPTTTLLITHIRFGFILHKDEAALQKIDLETMSYIKTINLKDYQCIPQSLAYTHLGGYYFIGCKPDSTGAAPPQLLVDGVTDSVIGFNSDVTGTPYVSPDGHYLVTISDVKGLVRVQYITIRGEIQEAFDIHTNLHISDLAFQPSFTEAHQYNIYGSSSTQTDVLFVELASGKVKMIKSLKEPLKAEEWPWNLKNRQIQDSGLFGQYLMTPSKDSLFILDGRLNKLNCEITEVEKGNTVIWVGEA", "length": 847, "header": "tr|G3N1L7-1|G3N1L7_BOVIN Isoform 1 of Follistatin-related protein 5 OS=Bos taurus OX=9913 GN=FSTL5 PE=4 SV=2 CANONICAL=G3N1L7-1" }, "locus": { "chromosome": "17", "start_pos": 37189198, "end_pos": 36318696, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000064567.3", "url": "https://www.ensembl.org/id/ENSBTAT00000064567.3" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000055765.2", "url": "https://www.ensembl.org/id/ENSBTAP00000055765.2" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [ { "id": "bta:782831", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?bta:782831", "resource": "KEGG Pathway" } ], "orthologs": [ { "uniprot_canonical_ac": "A0A096MK67-1", "protein_name": "Follistatin-related protein 5", "gene_name": "Fstl5", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MFKCWSAVLILGFIFLASEGRPTKESGYGLKYYQPLTRLRHKQEKSQESSRIKEFLIHDGPFGSCENKYCGLGRHCVISRETRHAECTCMDLCKQHYKPVCGSDGEFYENHCEVHRAACLKKQKITIVHNEDCFFKGDNCMTTEYSKMKSMLLDLQNQKYITQENENPNSDDISRKKTLVDQMFKYFDADSNGLVDINELTQVIKQEELNKDLSDCTLYDLLKYDDFNADKHLALEEFYRAFQVIQLSLPEDQRVSITAATVGQSAVLSCAVVGTLRPPIIWKRNNIVLNNLDLEDINDFGDDGSLYITKVTTVHMGNYTCYADGYEDVHQTHIFQVNVPPVIRVYPESQAREPGVTASLRCHAEGIPDPQLGWLKNGIDITPKLSKQLTLQANGSEVHISNVRYEDTGAYTCIARNEAGVDEDISSLFVEDSARKTLANILWREEGLGIGNMFYVFYDDGVKVIQPTECEFQRHIKPSEKLLGFQDEVCPKDEEDEVQRCVWASAVNVKDKFIYVAQPTLDRILIVDVQSQKVVQAVSTDPVPVKLHYDKSHDQVWVLSWGSMEKTSPTLQVITLASGNVPHHTIHTQPVGKQFDRVDDFFIPTPTLIITHMRFGFILHKDESALHKIDLETMSYIKTISLKDSKCIPLSLAYSHLGGYYFISCKPDITGAIPPQLVVDSVTDSIIGSNSDVTGTPYVSPDGHYLVSVNDVKGLVRVQYITIRGEILDAFDIHTNLHISDLAFQPSFTEAHQYNIYGSSSQQTDVLFVELSTGKVKMIKSLKEPLKTEDWPWSPKNRHIQGSGLFGQYLMTPSKDSLFILDGRLNKLNCEITEVQKGNTVVWVGDA", "length": 847 }, "evidence": [ { "id": "G3N1L7", "url": "https://omabrowser.org/oma/group/G3N1L7/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "A0A1D5PJN7-1", "protein_name": "Follistatin-related protein 5", "gene_name": "FSTL5", "tax_id": 9031, "organism": "Gallus gallus", "sequence": { "sequence": "MFMWWSAVLLLGWILFGADGWPAKEGYDFMPYQPLIRLRHKQEKNQESSRSKGYMDQDGHFKSCENKYCGLGRHCVMNGESGQAECVCMERCKPHYKPVCGSDGEFYENHCEVHRAACLKKQKVAIVHNEDCFFKGDKCKPTEYSKVKNMLLDLQNQRYAAQSKNRNVGEKMALRKLLVDQMFHYFDSDSNGLVDTNELSQVIKRDELGKDLSDCSLFDLLKYDDYNSDKHLGLEEFYRAFQIVQLSLPDDQKLSTTAATVGQSAVLSCAIQGALRPPIIWRRNNVILNNLDLEDINDFGDDGSLYITKVTTTHMGNYTCYADGYDKLYQTHILEVNVPPVIRVYPESQAREPGVTASLRCHAEGIPNPQLGWLKNGIDITPKLSKQLTLQANGSEVHISNVRYEDTGAYTCIAKNEAGVDEDISSLFVEDSARKTLANILWREQGLGIGNMFYVFYEDGIKVIQPVECEFQRHIKPSEKLLGFQDEVCPKTDGDSVQRCVWATAVNVKDKFIYVTQPTLDRVLIVDVQSQKVVQAVSTDPVPVKLHYDKSHDQVWVQSWGNMEKNSPTLQVITQASGSISHHTIHTQPVGKQFDRVDDFFIPATTLIITHIRFGFILHKDEPVLQKIDLETMSYIKTISLKDYNCIPQSLAYTHLGGFFFIYCKPDTTGAVLPQLIVDSVTDSVIGYNGDVTGRPHVSPDGHYLVSIDDAKGLMRIQTITMRGEILDAFDIHTNLHISDVAFQPSFTEAHQYNIYCSSSTQTDVLFVELSSGKVKMVKSLKEPVRAGEWPWNSKNRLIKDSGLFGQYLMTPSKESLFILDGRLNKLNCEITEVERGNTVIWVGEA", "length": 846 }, "evidence": [ { "id": "G3N1L7", "url": "https://omabrowser.org/oma/group/G3N1L7/", "database": "OMA" } ], "glygen_name": "Chicken", "common_name": "Chicken" }, { "uniprot_canonical_ac": "A0A480ZJN6-1", "protein_name": "Follistatin-related protein 5", "gene_name": "FSTL5", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MFKCWSAVLFLGFIFLESEGRPTKEAGYGLKSYQPLIRLRHKQEKSQESSRVKGFLIQNGPLGSCENKYCGLGRHCVLNRETGQAECACVDLCSQHYKPVCGSDGGFYENHCEVHRAACLKKRKITIVHNEDCFFQGDNCKATEYSKMKSMLLDLQNQKYITHNNENPNGDDIFRKKLLVDELFKYFDADSNGLVDINELTQVIKQEELDKDLSGCTLYDLLKYDDFNSDKHLALEEFYRTFQVIQLSLPEDQKLSITAATVGQSAVLSCAVQGALRPPIIWKRNNIILNNLELEDINDFGDDGSLYITKVTTTHMGNYTCYADGYEHIYQTHIFQVNVPPVIRVYPESQAREPGVTASLRCHAEGIPNPQLGWLKNGIDITPKLSKQLTLQANGSEVHISNVRYEDTGAYTCIAKNDAGVDEDISSLFVEDSARKTLANILWREEGLGIGNMFYVFYEDGIKVIQPIECEFQRHIKPSEKLLGFQDEVCPKTEGDEVQRCVWASAVNVKDKFIYAAQPTLDRVLVVDVQSQKVVQAVSTDPVPVKLHYDKSHDQVWVLSWGTMAKTSPTLQVITLASGNVPHHTIHTQPVGKQFDRVDDFFIPATTLLITHMRFGFILHKDEAALQKIDLETMSYIKTIHLKDYKCVPQSLAYTHLGGYYFIGCKPDSTGATPPQLLVDSVTDSVIGFNSDVTGTPYVSPDGHYLVSINDVKGLVRVQYITIRGEIQEAFDIHTNLHISDLAFQSSFTEAHQYNIYGSSSTQTDVLFAELASGKVKMIKSLKEPLKAEEWPWSQKNRQIQDSGLFGQYLMTPSKDSLFILDGRLNKLNCEITEVEKGNTVIWVGDA", "length": 847 }, "evidence": [ { "id": "G3N1L7", "url": "https://omabrowser.org/oma/group/G3N1L7/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "Q8BFR2-1", "protein_name": "Follistatin-related protein 5", "gene_name": "Fstl5", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MFRCWSAILILGFIFLASEGRPTKESGYGLKSYQPLTRLRHKQEKSQESSRIKEFLIHDGPFGSCENKYCGLGRHCVINRETRHAECACMDLCKQHYKPVCGSDGEFYENHCEVHRAACLKKQKITIVHNEDCFFEGDNCMAIEYSKMKSMLLDLQNQKYITQENENPNSDDISRKKPLVDQMFKYFDADSNGLVDINELTQVIKQEELNKDLSDCTLYDLLKYDDFNADKHLALEEFYRAFQVIQLSLPEDQRVSITAATVGQSAVLSCAIVGTLRPPIIWKRNNIVLNNLDLEDINDFGDDGSLYITKVTTVHMGNYTCYADGYENVRQTHIFQVNVPPVIRVYPESQAREPGVTASLRCHAEGIPDPQLGWLKNGIDITPKLSKQLTLQANGSEVHISNVRYEDTGAYTCIARNEAGVDEDISSLFVEDSARKTLANILWREEGLGIGNMFYVFYEDGIKVIQPTECEFQRHIKPSEKLLGYQDEVCPKAEEDEVQRCVWASAVNVKDKFIYVAQPTLDRILIVDVQSQKVVQAVSTDPVPVKLHYDKSHDQVWVLSWGSMEKTSPTLQVITLASGNVPHHTIHTQPVGKQFDRVDDFFIPTPTLIITHMRFGFILHKDESALHKIDLETMSYIKTINLKDSRCIPLSLAYTHLGGYYFISCKADITGATPPQLVVDSVTDSIIGFNSDVTGTPYVSPDGHYLVSVNDVKGLVRVQYITIRGEILDAFDIHTNLHISDLAFQPSFTEAHQYNIYGSSSQQTDVLFVELSSGKVKMIKSLKEPLKTEDWPWSQKNRHIQGSGLFGQYLMTPSKDSLFILDGRLNKLNCEITEVQKGNTVVWVGDA", "length": 847 }, "evidence": [ { "id": "G3N1L7", "url": "https://omabrowser.org/oma/group/G3N1L7/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q8N475-1", "protein_name": "Follistatin-related protein 5", "gene_name": "FSTL5", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MFKCWSVVLVLGFIFLESEGRPTKEGGYGLKSYQPLMRLRHKQEKNQESSRVKGFMIQDGPFGSCENKYCGLGRHCVTSRETGQAECACMDLCKRHYKPVCGSDGEFYENHCEVHRAACLKKQKITIVHNEDCFFKGDKCKTTEYSKMKNMLLDLQNQKYIMQENENPNGDDISRKKLLVDQMFKYFDADSNGLVDINELTQVIKQEELGKDLFDCTLYVLLKYDDFNADKHLALEEFYRAFQVIQLSLPEDQKLSITAATVGQSAVLSCAIQGTLRPPIIWKRNNIILNNLDLEDINDFGDDGSLYITKVTTTHVGNYTCYADGYEQVYQTHIFQVNVPPVIRVYPESQAREPGVTASLRCHAEGIPKPQLGWLKNGIDITPKLSKQLTLQANGSEVHISNVRYEDTGAYTCIAKNEAGVDEDISSLFVEDSARKTLANILWREEGLGIGNMFYVFYEDGIKVIQPIECEFQRHIKPSEKLLGFQDEVCPKAEGDEVQRCVWASAVNVKDKFIYVAQPTLDRVLIVDVQSQKVVQAVSTDPVPVKLHYDKSHDQVWVLSWGTLEKTSPTLQVITLASGNVPHHTIHTQPVGKQFDRVDDFFIPTTTLIITHMRFGFILHKDEAALQKIDLETMSYIKTINLKDYKCVPQSLAYTHLGGYYFIGCKPDSTGAVSPQVMVDGVTDSVIGFNSDVTGTPYVSPDGHYLVSINDVKGLVRVQYITIRGEIQEAFDIYTNLHISDLAFQPSFTEAHQYNIYGSSSTQTDVLFVELSSGKVKMIKSLKEPLKAEEWPWNRKNRQIQDSGLFGQYLMTPSKDSLFILDGRLNKLNCEITEVEKGNTVIWVGDA", "length": 847 }, "evidence": [ { "id": "G3N1L7", "url": "https://omabrowser.org/oma/group/G3N1L7/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" } ], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 1, "go_terms": [ { "name": "extracellular region", "id": "GO:0005576", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005576", "evidence": [ { "database": "UniProtKB", "id": "G3N1L7", "url": "https://www.uniprot.org/uniprotkb/G3N1L7" } ], "pmid": "" } ] }, { "name": "Molecular Function", "total": 1, "go_terms": [ { "name": "calcium ion binding", "id": "GO:0005509", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005509", "evidence": [ { "database": "UniProtKB", "id": "G3N1L7", "url": "https://www.uniprot.org/uniprotkb/G3N1L7" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 2, "go_terms": [ { "name": "cell differentiation", "id": "GO:0030154", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030154", "evidence": [ { "database": "UniProtKB", "id": "G3N1L7", "url": "https://www.uniprot.org/uniprotkb/G3N1L7" } ], "pmid": "" }, { "name": "regulation of BMP signaling pathway", "id": "GO:0030510", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030510", "evidence": [ { "database": "UniProtKB", "id": "G3N1L7", "url": "https://www.uniprot.org/uniprotkb/G3N1L7" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 318, "end_pos": 320, "annotation": "n_glycosylation_sequon" }, { "start_pos": 394, "end_pos": 396, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [ { "pdb_id": "AF-G3N1L7-F1", "pdb_chain": "global", "start_pos": 1, "end_pos": 847, "overlap": "1.0", "method": "AlphaFold", "type": "alphafold", "resolution": -1.0, "url": "https://data.glygen.org/ln2downloads/pdb/current/AF-G3N1L7-F1.pdb", "url_external": "https://alphafold.ebi.ac.uk/entry/G3N1L7" } ], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "G3N1L7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3N1L7" }, { "id": "PS50222", "database": "PROSITE", "url": "https://prosite.expasy.org/PS50222" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "EF-hand", "eco_id": "ECO_0000259", "start_pos": 175, "end_pos": 210, "start_aa": "Arg", "end_aa": "Gly", "glycosite_overlap": [] }, { "evidence": [ { "id": "G3N1L7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3N1L7" }, { "id": "PS50835", "database": "PROSITE", "url": "https://prosite.expasy.org/PS50835" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "Ig-like", "eco_id": "ECO_0000259", "start_pos": 250, "end_pos": 324, "start_aa": "Pro", "end_aa": "Glu", "glycosite_overlap": [] }, { "evidence": [ { "id": "G3N1L7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3N1L7" }, { "id": "PS51465", "database": "PROSITE", "url": "https://prosite.expasy.org/PS51465" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "Kazal-like", "eco_id": "ECO_0000259", "start_pos": 88, "end_pos": 135, "start_aa": "Ala", "end_aa": "Phe", "glycosite_overlap": [] } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" }, { "name": "homologset.oma", "label": "OMA Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 318, "end_pos": 320 }, { "start_pos": 394, "end_pos": 396 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ], "tool_support": { "graph_view": "yes" } }, { "uniprot_canonical_ac": "G3X769-1", "uniprot_ac": "G3X769", "uniprot_id": "G3X769_BOVIN", "mass": { "chemical_mass": 54393.0, "monoisotopic_mass": 54393.0 }, "refseq": {}, "gene_names": [], "protein_names": [ { "name": "Uncharacterized protein", "type": "synonym", "evidence": [ { "id": "G3X769", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3X769/entry#names_and_taxonomy" } ] } ], "function": [], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Bos taurus", "taxid": 9913, "evidence": [ { "database": "UniProtKB", "id": "G3X769", "url": "https://www.uniprot.org/uniprotkb/G3X769" } ], "common_name": "Bovine", "glygen_name": "Bovine", "reference_species": "Bos taurus [9913]" } ], "gene": [ { "name": "", "url": "https://www.uniprot.org/uniprotkb/G3X769", "locus": {} } ], "crossref": [ { "id": "G3X769", "url": "https://alphafold.ebi.ac.uk/entry/G3X769", "database": "AlphaFoldDB", "categories": [] }, { "id": "ENSBTAG00000031507", "url": "https://bgee.org/?page=gene&gene_id=ENSBTAG00000031507", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "IPR026271", "url": "https://www.ebi.ac.uk/interpro/entry/IPR026271", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR032675", "url": "https://www.ebi.ac.uk/interpro/entry/IPR032675", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR050694", "url": "https://www.ebi.ac.uk/interpro/entry/IPR050694", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "NHISMAT", "url": "https://omabrowser.org/oma/group/NHISMAT/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "A0A3Q1MCY8", "url": "https://www.orthodb.org/?gene=A0A3Q1MCY8", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "G3X769", "url": "https://www.orthodb.org/?gene=G3X769", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR14224", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR14224", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR14224:SF102", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR14224:SF102", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF27089", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF27089", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF27091", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF27091", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "A0A3Q1MCY8", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1MCY8", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A3Q1MCY8-1", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1MCY8-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "G3X769", "url": "https://www.uniprot.org/uniprotkb/G3X769", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "G3X769-1", "url": "https://www.uniprot.org/uniprotkb/G3X769-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MMSVPTPPRLLDLAGMHLIKEDALVCSALEFLPTELFPPLFMDAFRGRHIKTLKAMVQAWPFVCLPLGGLIDLPHVGPLQAVLEALDVLLAQKVRSRRCKLRVLDLRNTGQSFWSMWSGASTHGFSRLGMAPVAEQSSKTHQPLAPLKIYIELCLKKMTLDNFLTYLLRWMEQRKASIHLCCKKLTIFAMPVENVMKVLNMVQLDCIQEVQVNWIWHLSTLAKFAPLLGQMSNVQRLLLSRSHVSALEKQEQQEQVVQFTSQFLKLHHLQDLYLDSPSFLEGCLDQMLRCLMTPLDHLAITNCRLTESDLTHLSQCPNIHQLKGLDLSGVTMTDFSPKILCILLEQVAATLQELNLEQCGITESRLESILPVLSCCSQLRTFSLCGNVLSMAIMEKLLSHTTGLFYLSDEFYPAPQESYSPHGALHLGRLAKLRDKLIEIMRDLGRPRAIWLSSSPCPRWSNKTFYPEEPFLYQCYMSA", "length": 479, "header": "tr|G3X769-1|G3X769_BOVIN Isoform 1 of Uncharacterized protein OS=Bos taurus OX=9913 GN= PE=3 SV=2 CANONICAL=G3X769-1" }, "isoforms": [ { "isoform_ac": "A0A3Q1MCY8-1", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1MCY8/entry", "sequence": { "sequence": "MSVPTPPRLLDLAGMHLIKEDALVCSALEFLPTELFPPLFMDAFRGRHIKTLKAMVQAWPFVCLPLGGLIDLPHVGPLQAVLEALDVLLAQKVRSRCKLRVLDLRNTGQSFWSMWSGASTHGFSRLGMAPVAEQSSKTHQPLAPLKIYIELCLKKMTLDNFLTYLLRWMEQRKASIHLCCKKLTIFAMPVENVMKVLNMVQLDCIQEVQVNWIWHLSTLAKFAPLLGQMSNVQRLLLSRSHVSALEKQEQQEQVVQFTSQFLKLHHLQDLYLDSPSFLEGCLDQMLRCLMTPLDHLAITNCRLTESDLTHLSQCPNIHQLKGLDLSGVTMTDFSPKILCILLEQVAATLQELNLEQCGITESRLESILPVLSCCSQLRTFSLCGNVLSMAIMEKLLSHTTGLFYLSDDCPHGSPGGSVGLSSWPFCAGKGV", "length": 431, "header": "tr|A0A3Q1MCY8-1|G3X769_BOVIN Computationally mapped isoform of Uncharacterized protein OS=Bos taurus OX=9913 GN= PE=3 SV=2 CANONICAL=G3X769-1" }, "locus": { "chromosome": "16", "start_pos": 54376089, "end_pos": 54372658, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000073281.2", "url": "https://www.ensembl.org/id/ENSBTAT00000073281.2" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000068244.2", "url": "https://www.ensembl.org/id/ENSBTAP00000068244.2" } ] } }, { "isoform_ac": "G3X769-1", "url": "https://www.uniprot.org/uniprotkb/G3X769/entry", "sequence": { "sequence": "MMSVPTPPRLLDLAGMHLIKEDALVCSALEFLPTELFPPLFMDAFRGRHIKTLKAMVQAWPFVCLPLGGLIDLPHVGPLQAVLEALDVLLAQKVRSRRCKLRVLDLRNTGQSFWSMWSGASTHGFSRLGMAPVAEQSSKTHQPLAPLKIYIELCLKKMTLDNFLTYLLRWMEQRKASIHLCCKKLTIFAMPVENVMKVLNMVQLDCIQEVQVNWIWHLSTLAKFAPLLGQMSNVQRLLLSRSHVSALEKQEQQEQVVQFTSQFLKLHHLQDLYLDSPSFLEGCLDQMLRCLMTPLDHLAITNCRLTESDLTHLSQCPNIHQLKGLDLSGVTMTDFSPKILCILLEQVAATLQELNLEQCGITESRLESILPVLSCCSQLRTFSLCGNVLSMAIMEKLLSHTTGLFYLSDEFYPAPQESYSPHGALHLGRLAKLRDKLIEIMRDLGRPRAIWLSSSPCPRWSNKTFYPEEPFLYQCYMSA", "length": 479, "header": "tr|G3X769-1|G3X769_BOVIN Isoform 1 of Uncharacterized protein OS=Bos taurus OX=9913 GN= PE=3 SV=2 CANONICAL=G3X769-1" }, "locus": { "chromosome": "16", "start_pos": 54376141, "end_pos": 54373337, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000020712.4", "url": "https://www.ensembl.org/id/ENSBTAT00000020712.4" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000020712.4", "url": "https://www.ensembl.org/id/ENSBTAP00000020712.4" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [], "orthologs": [], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 2, "go_terms": [ { "name": "cytoplasm", "id": "GO:0005737", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005737", "evidence": [ { "database": "UniProtKB", "id": "G3X769", "url": "https://www.uniprot.org/uniprotkb/G3X769" } ], "pmid": "" }, { "name": "Cul2-RING ubiquitin ligase complex", "id": "GO:0031462", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0031462", "evidence": [ { "database": "UniProtKB", "id": "G3X769", "url": "https://www.uniprot.org/uniprotkb/G3X769" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 5, "go_terms": [ { "name": "positive regulation of cell population proliferation", "id": "GO:0008284", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008284", "evidence": [ { "database": "UniProtKB", "id": "G3X769", "url": "https://www.uniprot.org/uniprotkb/G3X769" } ], "pmid": "" }, { "name": "negative regulation of apoptotic process", "id": "GO:0043066", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0043066", "evidence": [ { "database": "UniProtKB", "id": "G3X769", "url": "https://www.uniprot.org/uniprotkb/G3X769" } ], "pmid": "" }, { "name": "negative regulation of DNA-templated transcription", "id": "GO:0045892", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0045892", "evidence": [ { "database": "UniProtKB", "id": "G3X769", "url": "https://www.uniprot.org/uniprotkb/G3X769" } ], "pmid": "" }, { "name": "proteasome-mediated ubiquitin-dependent protein catabolic process", "id": "GO:0043161", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0043161", "evidence": [ { "database": "UniProtKB", "id": "G3X769", "url": "https://www.uniprot.org/uniprotkb/G3X769" } ], "pmid": "" }, { "name": "negative regulation of cell differentiation", "id": "GO:0045596", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0045596", "evidence": [ { "database": "UniProtKB", "id": "G3X769", "url": "https://www.uniprot.org/uniprotkb/G3X769" } ], "pmid": "" } ] }, { "name": "Molecular Function", "total": 1, "go_terms": [ { "name": "ubiquitin-like ligase-substrate adaptor activity", "id": "GO:1990756", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:1990756", "evidence": [ { "database": "UniProtKB", "id": "G3X769", "url": "https://www.uniprot.org/uniprotkb/G3X769" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 462, "end_pos": 464, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 462, "end_pos": 464 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ], "tool_support": { "graph_view": "yes" } }, { "uniprot_canonical_ac": "G3X7B8-1", "uniprot_ac": "G3X7B8", "uniprot_id": "G3X7B8_BOVIN", "mass": { "chemical_mass": 24032.0, "monoisotopic_mass": 24032.0 }, "refseq": { "ac": "XP_015330487", "name": "C4b-binding protein beta chain isoform X1", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_015330487" }, "gene_names": [ { "name": "C4BPB", "type": "recommended", "evidence": [ { "id": "G3X7B8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3X7B8" } ] }, { "name": "C4BPB", "type": "synonym", "evidence": [ { "id": "XP_015330487", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_015330487" } ] } ], "protein_names": [ { "name": "C4b-binding protein beta chain isoform X1", "type": "synonym", "evidence": [ { "id": "XP_015330487", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_015330487" } ] }, { "name": "Complement component 4 binding protein beta", "type": "synonym", "evidence": [ { "id": "G3X7B8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3X7B8/entry#names_and_taxonomy" } ] } ], "function": [], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Bos taurus", "taxid": 9913, "evidence": [ { "database": "UniProtKB", "id": "G3X7B8", "url": "https://www.uniprot.org/uniprotkb/G3X7B8" } ], "common_name": "Bovine", "glygen_name": "Bovine", "reference_species": "Bos taurus [9913]" } ], "gene": [ { "name": "C4BPB", "url": "https://www.uniprot.org/uniprotkb/G3X7B8", "locus": { "chromosome": "16", "start_pos": 4925086, "end_pos": 4913856, "strand": "-", "evidence": [ { "database": "Ensembl Gene", "id": "ENSBTAG00000017714", "url": "https://www.ensembl.org/id/ENSBTAG00000017714" } ] } } ], "crossref": [ { "id": "G3X7B8", "url": "https://alphafold.ebi.ac.uk/entry/G3X7B8", "database": "AlphaFoldDB", "categories": [] }, { "id": "ENSBTAG00000017714", "url": "https://bgee.org/?page=gene&gene_id=ENSBTAG00000017714", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "cd00033", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd00033", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "281652", "url": "https://www.ncbi.nlm.nih.gov/gene/281652", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR000436", "url": "https://www.ebi.ac.uk/interpro/entry/IPR000436", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR035976", "url": "https://www.ebi.ac.uk/interpro/entry/IPR035976", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "A0A3Q1MCY9", "url": "https://www.orthodb.org/?gene=A0A3Q1MCY9", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "G3X7B8", "url": "https://www.orthodb.org/?gene=G3X7B8", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR46393", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR46393", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR46393:SF7", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR46393:SF7", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00084", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00084", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "XP_015330487", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_015330487", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A3Q1MCY9", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1MCY9", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A3Q1MCY9-1", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1MCY9-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0AAA9TVY0", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TVY0", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0AAA9TVY0-1", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TVY0-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "G3X7B8", "url": "https://www.uniprot.org/uniprotkb/G3X7B8", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "G3X7B8-1", "url": "https://www.uniprot.org/uniprotkb/G3X7B8-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MDEREGDTCLKRGLKNFEQCLTEENDERAIVGHCPDPLLVTDEFSSLEPVNVNDTFMFKCNEHCIFKGSNWSQCRENHTRVTHSPVSKSRDCGPPETPTHGYFEGRDFKSGSTITYYCQARYRLVGTQHQQCIDGEWTSAPPICELIQEAPKPAELELEKAFLAFQESKELCKAIKKFTQRLKKSDLTMEKVKYSLERKKAKLKAKMLL", "length": 209, "header": "tr|G3X7B8-1|G3X7B8_BOVIN Isoform 1 of Complement component 4 binding protein beta OS=Bos taurus OX=9913 GN=C4BPB PE=4 SV=2 CANONICAL=G3X7B8-1" }, "isoforms": [ { "isoform_ac": "A0A3Q1MCY9-1", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1MCY9/entry", "sequence": { "sequence": "MGHCPDPLLVTDEFSSLEPVNVNDTFMFKCNEHCIFKGSNWSQCRENHTRVTHSPVSKSRDCGPPETPTHGYFEGRDFKSGSTITYYCQARYRLVGTQHQQCIDGEWTSAPPICELIQEAPKPAELELEKAFLAFQESKELCKAIKKFTQRLKKSDLTMEKVKYSLERKKAKLKAKMLL", "length": 179, "header": "tr|A0A3Q1MCY9-1|G3X7B8_BOVIN Computationally mapped isoform of Complement component 4 binding protein beta OS=Bos taurus OX=9913 GN=C4BPB PE=4 SV=2 CANONICAL=G3X7B8-1" }, "locus": { "chromosome": "16", "start_pos": 4925019, "end_pos": 4914675, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000073282.2", "url": "https://www.ensembl.org/id/ENSBTAT00000073282.2" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000066677.2", "url": "https://www.ensembl.org/id/ENSBTAP00000066677.2" } ] } }, { "isoform_ac": "A0AAA9TVY0-1", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TVY0/entry", "sequence": { "sequence": "MFFWLMCYLVDVWLISASDVGHCPDPLLVTDEFSSLEPVNVNDTFMFKCNEHCIFKGSNWSQCRENHTRVTHSPVSKSRDCGPPETPTHGYFEGRDFKSGSTITYYCQARYRLVGTQHQQCIDGEWTSAPPICELIQEAPKPAELELEKAFLAFQESKELCKAIKKFTQRLKKSDLTMEKVKYSLERKKAKLKAKMLL", "length": 198, "header": "tr|A0AAA9TVY0-1|G3X7B8_BOVIN Computationally mapped isoform of Complement component 4 binding protein beta OS=Bos taurus OX=9913 GN=C4BPB PE=4 SV=2 CANONICAL=G3X7B8-1" }, "locus": { "chromosome": "16", "start_pos": 4925019, "end_pos": 4914131, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000131935.2", "url": "https://www.ensembl.org/id/ENSBTAT00000131935.2" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000102498.2", "url": "https://www.ensembl.org/id/ENSBTAP00000102498.2" } ] } }, { "isoform_ac": "G3X7B8-1", "url": "https://www.uniprot.org/uniprotkb/G3X7B8/entry", "sequence": { "sequence": "MDEREGDTCLKRGLKNFEQCLTEENDERAIVGHCPDPLLVTDEFSSLEPVNVNDTFMFKCNEHCIFKGSNWSQCRENHTRVTHSPVSKSRDCGPPETPTHGYFEGRDFKSGSTITYYCQARYRLVGTQHQQCIDGEWTSAPPICELIQEAPKPAELELEKAFLAFQESKELCKAIKKFTQRLKKSDLTMEKVKYSLERKKAKLKAKMLL", "length": 209, "header": "tr|G3X7B8-1|G3X7B8_BOVIN Isoform 1 of Complement component 4 binding protein beta OS=Bos taurus OX=9913 GN=C4BPB PE=4 SV=2 CANONICAL=G3X7B8-1" }, "locus": { "chromosome": "16", "start_pos": 4925019, "end_pos": 4914186, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000023558.6", "url": "https://www.ensembl.org/id/ENSBTAT00000023558.6" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000023558.4", "url": "https://www.ensembl.org/id/ENSBTAP00000023558.4" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [], "orthologs": [], "go_annotation": {}, "pro_annotation": [], "site_annotation": [ { "start_pos": 53, "end_pos": 55, "annotation": 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}, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": 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"table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ], "tool_support": { "graph_view": "yes" } }, { "uniprot_canonical_ac": "G3X711-1", "uniprot_ac": "G3X711", "uniprot_id": "G3X711_BOVIN", "mass": { "chemical_mass": 59872.0, "monoisotopic_mass": 59872.0 }, "refseq": {}, "gene_names": [ { "name": "BTBD6", "type": "recommended", "evidence": [ { "id": "G3X711", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3X711" } ] } ], "protein_names": [ { "name": "BTB domain containing 6", "type": "synonym", "evidence": [ { "id": "G3X711", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3X711/entry#names_and_taxonomy" } ] } ], "function": [], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Bos taurus", "taxid": 9913, "evidence": [ { "database": "UniProtKB", "id": "G3X711", "url": "https://www.uniprot.org/uniprotkb/G3X711" } ], "common_name": "Bovine", "glygen_name": "Bovine", "reference_species": "Bos taurus [9913]" } ], "gene": [ { "name": "BTBD6", "url": "https://www.uniprot.org/uniprotkb/G3X711", "locus": { "chromosome": "21", "start_pos": 69577603, "end_pos": 69573552, "strand": "-", "evidence": [ { "database": "Ensembl Gene", "id": "ENSBTAG00000012751", "url": "https://www.ensembl.org/id/ENSBTAG00000012751" } ] } } ], "crossref": [ { "id": "G3X711", "url": "https://alphafold.ebi.ac.uk/entry/G3X711", "database": "AlphaFoldDB", "categories": [] }, { "id": "ENSBTAG00000012751", "url": "https://bgee.org/?page=gene&gene_id=ENSBTAG00000012751", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "cd18349", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd18349", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "cd18525", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd18525", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "IPR000210", "url": "https://www.ebi.ac.uk/interpro/entry/IPR000210", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR011333", "url": "https://www.ebi.ac.uk/interpro/entry/IPR011333", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR011705", "url": "https://www.ebi.ac.uk/interpro/entry/IPR011705", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR012983", "url": "https://www.ebi.ac.uk/interpro/entry/IPR012983", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR038648", "url": "https://www.ebi.ac.uk/interpro/entry/IPR038648", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR049738", "url": "https://www.ebi.ac.uk/interpro/entry/IPR049738", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "PTHR45774", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR45774", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR45774:SF5", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR45774:SF5", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00651", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00651", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF07707", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF07707", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF08005", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF08005", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "A0A3Q1MGU1", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1MGU1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A3Q1MGU1-1", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1MGU1-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A3Q1N1Y8", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1N1Y8", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A3Q1N1Y8-1", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1N1Y8-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "G3X711", "url": "https://www.uniprot.org/uniprotkb/G3X711", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "G3X711-1", "url": "https://www.uniprot.org/uniprotkb/G3X711-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MLLPLACLHGRVAQCLTALLVLAEPPPRPRRGARAHGAPLPRAEAALPAKMAAELYAPASAAAAAAATATDIANSNAAAAAAAAGRKGRPSAPLPAPPPPAPAPPPPDNNNPESPNWQSFHPTLRERNALMFNNELMADVHFVVGPPGAARRVPAHKYVLAVGSSVFYAMFYGDLAEVKSEIHIPDVEPAAFLILLKYMYSDEIDLEADTVLATLYAAKKYIVPALAKACVNFLETSLEAKNACVLLSQSRLFEEPELTQRCWEVIDAQAEMALRSEGFCEIDWQTLEIIVTREALNTKEAVVFEAVLSWAEAECKRQGLPATPRNKRHVLGPALYLVRIPTMTLEEFANGAAQSDILTLEETHNIFLWYTAANKPLLEFPLTKRKGLAPQRCHRFQSSAYRSNQWRYRGRCDSIQFAVDRRVFVAGLGLYGSSSGKAEYSVKIELKRLGVVLAQNLTKFVSDGSSNTFSVWFEHPVQVEQDTFYTASAVLDGSELSYFGQEGMTEGSACYILSTRKCASRHPWATEQSLQPTEEECLAQHVNVHLS", "length": 547, "header": "tr|G3X711-1|G3X711_BOVIN Isoform 1 of BTB domain containing 6 OS=Bos taurus OX=9913 GN=BTBD6 PE=4 SV=1 CANONICAL=G3X711-1" }, "isoforms": [ { "isoform_ac": "A0A3Q1MGU1-1", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1MGU1/entry", "sequence": { "sequence": "MLLPLACLHGRVAQCLTALLVLAEPPPRPRRGARAHGAPLPRAEAALPAKMAAELYAPASAAAAAAATATDIANSNAAAAAAAAGRKGRPSAPLPAPPPPAPAPPPPDNNNPESPNWQSFHPTLRERNALMFNNELMADVHFVVGPPGAARRVPAHKYVLAVGSSVFYAMFYGDLAEVKSEIHIPDVEPAAFLILLNDEIDLEADTVLATLYAAKKYIVPALAKACVNFLETSLEAKNACVLLSQSRLFEEPELTQRCWEVIDAQAEMALRSEGFCEIDWQTLEIIVTREALNTKEAVVFEAVLSWAEAECKRQGLPATPRNKRHVLGPALYLVRIPTMTLEEFANGAAQSDILTLEETHNIFLWYTAANKPLLEFPLTKRKGLAPQRCHRFQSSAYRSNQWRYRGRCDSIQFAVDRRVFVAGLGLYGSSSGKAEYSVKIELKRLGVVLAQNLTKFVSDGSSNTFSVWFEHPVQVEQDTFYTASAVLDGSELSYFGQEGMTEVQCGKVTFQFQCSSDSTNGTGVQGGQIPELIFYA", "length": 536, "header": "tr|A0A3Q1MGU1-1|G3X711_BOVIN Computationally mapped isoform of BTB domain containing 6 OS=Bos taurus OX=9913 GN=BTBD6 PE=4 SV=1 CANONICAL=G3X711-1" }, "locus": { "chromosome": "21", "start_pos": 69575759, "end_pos": 69573751, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000066976.2", "url": "https://www.ensembl.org/id/ENSBTAT00000066976.2" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000068253.2", "url": "https://www.ensembl.org/id/ENSBTAP00000068253.2" } ] } }, { "isoform_ac": "A0A3Q1N1Y8-1", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1N1Y8/entry", "sequence": { "sequence": "MLLPLACLHGRVAQCLTALLVLAEPPPRPRRGARAHGAPLPRAEAALPAKMAAELYAPASAAAAAAATATDIANSNAAAAAAAAGRKGRPSAPLPAPPPPAPAPPPPDNNNPESPNWQSFHPTLRERNALMFNNELMADVHFVVGPPGAARRVPAHKYVLAVGSSVFYAMFYGDLAEVKSEIHIPDVEPAAFLILLKYMYSDEIDLEADTVLATLYAAKKYIVPALAKACVNFLETSLEAKNACVLLSQSRLFEEPELTQRCWEVIDAQAEMALRSEGFCEIDWQTLEIIVTREALNTKEAVVFEAVLSWAEAECKRQGLPATPRNKRHVLGPALYLVRIPTMTLEEFANGAAQSDILTLEETHNIFLWYTAANKPLLEFPLTKRKGLAPQRCHRFQSSAYRSNQWRYRGRCDSIQFAVDRRVFVAGLGLYGSSSGKAEYSVKIELKRLGVVLAQNLTKFVSDGSSNTFSVWFEHPVQVEQDTFYTASAVLDGSELSYFGQEGMTEEEECLAQHVNVHLS", "length": 520, "header": "tr|A0A3Q1N1Y8-1|G3X711_BOVIN Computationally mapped isoform of BTB domain containing 6 OS=Bos taurus OX=9913 GN=BTBD6 PE=4 SV=2 CANONICAL=G3X711-1" }, "locus": { "chromosome": "21", "start_pos": 69577207, "end_pos": 69573751, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000068367.2", "url": "https://www.ensembl.org/id/ENSBTAT00000068367.2" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000063187.2", "url": "https://www.ensembl.org/id/ENSBTAP00000063187.2" } ] } }, { "isoform_ac": "G3X711-1", "url": "https://www.uniprot.org/uniprotkb/G3X711/entry", "sequence": { "sequence": "MLLPLACLHGRVAQCLTALLVLAEPPPRPRRGARAHGAPLPRAEAALPAKMAAELYAPASAAAAAAATATDIANSNAAAAAAAAGRKGRPSAPLPAPPPPAPAPPPPDNNNPESPNWQSFHPTLRERNALMFNNELMADVHFVVGPPGAARRVPAHKYVLAVGSSVFYAMFYGDLAEVKSEIHIPDVEPAAFLILLKYMYSDEIDLEADTVLATLYAAKKYIVPALAKACVNFLETSLEAKNACVLLSQSRLFEEPELTQRCWEVIDAQAEMALRSEGFCEIDWQTLEIIVTREALNTKEAVVFEAVLSWAEAECKRQGLPATPRNKRHVLGPALYLVRIPTMTLEEFANGAAQSDILTLEETHNIFLWYTAANKPLLEFPLTKRKGLAPQRCHRFQSSAYRSNQWRYRGRCDSIQFAVDRRVFVAGLGLYGSSSGKAEYSVKIELKRLGVVLAQNLTKFVSDGSSNTFSVWFEHPVQVEQDTFYTASAVLDGSELSYFGQEGMTEGSACYILSTRKCASRHPWATEQSLQPTEEECLAQHVNVHLS", "length": 547, "header": "tr|G3X711-1|G3X711_BOVIN Isoform 1 of BTB domain containing 6 OS=Bos taurus OX=9913 GN=BTBD6 PE=4 SV=1 CANONICAL=G3X711-1" }, "locus": { "chromosome": "21", "start_pos": 69577207, "end_pos": 69573751, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000016949.7", "url": "https://www.ensembl.org/id/ENSBTAT00000016949.7" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000016949.6", "url": "https://www.ensembl.org/id/ENSBTAP00000016949.6" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [], "orthologs": [], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 1, "go_terms": [ { "name": "cytoplasm", "id": "GO:0005737", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005737", "evidence": [ { "database": "UniProtKB", "id": "G3X711", "url": "https://www.uniprot.org/uniprotkb/G3X711" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 456, "end_pos": 458, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "G3X711", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3X711" }, { "id": "PS50097", "database": "PROSITE", "url": "https://prosite.expasy.org/PS50097" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "BTB", "eco_id": "ECO_0000259", "start_pos": 138, "end_pos": 208, "start_aa": "Ala", "end_aa": "Ala", "glycosite_overlap": [] } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 456, "end_pos": 458 } ] }, "class_list": [], 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"length": 1589, "header": "tr|A0A3Q1MH42-1|G3X6H0_BOVIN Computationally mapped isoform of Centrosomal protein 170B OS=Bos taurus OX=9913 GN=CEP170B PE=3 SV=2 CANONICAL=G3X6H0-1" }, "locus": { "chromosome": "21", "start_pos": 69335184, "end_pos": 69314613, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000082875.3", "url": "https://www.ensembl.org/id/ENSBTAT00000082875.3" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000070540.2", "url": "https://www.ensembl.org/id/ENSBTAP00000070540.2" } ] } }, { "isoform_ac": "G3X6H0-1", "url": "https://www.uniprot.org/uniprotkb/G3X6H0/entry", "sequence": { "sequence": "MGRALGLPTSSFALQPSLGRAGPKGRTGLMSAKMSVTSWFLVSSSGTRHRLPRELIFVGRDECELMLQSRSVDKQHAVINYDQDRDEHWVKDLGSLNGTFVNDVRIPDQRYVTLKLNDVIRFGYDPNMYVLERVQHRVPEEALRHEKYTSQLQVSVKTPAPKRAEAVPEQAPYCEASTPRPERGDRRPGPEAATYRTPLYGQPSWWGEDDGGSLPEDRHQDEPCPERPKDLAQQDGDLTGTPAGFRAPSEPQIYSFRREPSYFEIPTKETPPPRPPEAPVHEAPTRDAEPGGGGAGPVQSHACFTIEFDDCSPGKLKIKDHVTKFLRQRRPPGKEATPVEVVSAETKVADWLVQNDPSLLPRAGPGDDRHSTKSDLPVHARTLKGHKHEDGTQSDSEDPLAKVAGAPGVPAEASGEQARLQRQIKRDPQELLHNQQAFVIEFFDEDTPRKKRSQSFTHTPPGDPRLDRRRGPGPADRDRPAAPAPARGTGSSSGPQRAGSLKREKTEERLGSPSPATRAAARPFGSVGRRSRLAQDFAAQCLRDSSPAARPGPEKVPPTLPAPLTPRGASPAASSPPPPPPADPQVTKARKQEEDDSLSDAGTYTIETDAQDQEVEEARKMIDQVFGVLESPELSRASSAAFRPVIRGDREELGDGMAHRMALLQEFASRPAGVTPQVELQGLPVPGSPGGQKWVSRWASLADSYSDPGLSEDGPGHRAAELEGIPPMRPRRLLPQLPSDRADSPAGPEVARRSGPGPPEVGSEQAGLLLGQEDLEPDSLSDASGSDGGPGPEPGGGPQEERRRSPQEGPAWTRGRRSPRGPGEPAPTSFFISDPSADAALPRKAPVAPGQVEGPGRAQPSAPAPAPAPAPAHDSKYVSTSGRMVIQLQTTGKPPELEGPAPAPTKEALAFVRQESFTKEPASGPAVPGQLPQIPSHPLLQDLATTRAARMDLHSQDTHLILKETETALAALEARLLSKSFEEPEGGVGSAPGPPEDSLSGDSDVDTASTVSLLSGKNGPSPTGSQPSGLQREKPPSPPAAQDLGGVSLSSARERLSEKQRRPLGPVDTGHGEPARRLAARRGHGPRGSPDWPAEDRDSSLAHPPSADTVTSDHETPGATGAARPGTRRKPMAPPPPTTAAREEQGRGSAGVQKSQQALTRSNSLSTPRATRASRLRRARLGDASDTEAADGERGPPANQEPAGRPAAEQAKKLSRLDILAMPRKRAGSFTGPSDSEAAPTRAGFSGRSVELYCPGRKPTTMAEARPTARKATNAAAVPRQPFSRARPGSARYSSPNTRRRQQGSDCTSTSEEEYGSHHGSPKHTRSHASTATQTPRAGGSGRARPRAPGLRDTDDEGEEPDPYGFIVQTAEIAEIARLSQTLVKDVATLAREIHDVAGDGDSPGSPGPARSPSLNNVPSTPASTISAREELVQRIPEASLNFQKVPPGSLGPRDLDQNMNDRCEDALANKTRPRNREEVIFDNLMLNPVSQLSQAIRENTEHLAEKMKILFQNSGRAWEDLEARINAENEVPILKTSNKEISSILKELRRVQKQLEVINAIVDPSGNLDLLTGNRGPVGSAQVGRARPAAPGLCSPSSALPPRSFPQRTSCGTPGLPDPPLRPDFLPDAERFLI", "length": 1635, "header": "tr|G3X6H0-1|G3X6H0_BOVIN Isoform 1 of Centrosomal protein 170B OS=Bos taurus OX=9913 GN=CEP170B PE=3 SV=3 CANONICAL=G3X6H0-1" }, "locus": { "chromosome": "21", "start_pos": 69335184, "end_pos": 69311772, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000006305.8", "url": "https://www.ensembl.org/id/ENSBTAT00000006305.8" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000006305.7", "url": "https://www.ensembl.org/id/ENSBTAP00000006305.7" } ] } } ], "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "other", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 1138, "start_aa": "Thr", "end_pos": 1138, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr1138", "evidence": [ { "id": "", "database": "GlyGen", "url": "https://data.glygen.org/" } ], "filter_code": "000000000000000010000.00000000001000.0.01000" }, { "glytoucan_ac": "", "type": "O-linked", "subtype": "other", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 1421, "start_aa": "Thr", "end_pos": 1421, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr1421", "evidence": [ { "id": "", "database": "GlyGen", "url": "https://data.glygen.org/" } ], "filter_code": "000000000000000010000.00000000001000.0.01000" }, { "glytoucan_ac": "", "type": "O-linked", "subtype": "other", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 1614, "start_aa": "Thr", "end_pos": 1614, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr1614", "evidence": [ { "id": "", "database": "GlyGen", "url": "https://data.glygen.org/" } ], "filter_code": "000000000000000010000.00000000001000.0.01000" } ], "phosphorylation": [], "glycation": [], "keywords": [ "glycoprotein", "glycoprotein_predicted" ], "publication": [], "pathway": [], "orthologs": [], "go_annotation": {}, "pro_annotation": [], "site_annotation": [ { "start_pos": 1470, "end_pos": 1472, "annotation": "n_glycosylation_sequon" }, { "start_pos": 97, "end_pos": 99, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "G3X6H0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3X6H0" }, { "id": "PS50006", "database": "PROSITE", "url": 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"url": "https://www.uniprot.org/uniprotkb/G3N3U7" } ] } ], "protein_names": [ { "name": "Eukaryotic translation initiation factor 4E binding protein 3", "type": "synonym", "evidence": [ { "id": "G3N3U7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3N3U7/entry#names_and_taxonomy" } ] } ], "function": [], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Bos taurus", "taxid": 9913, "evidence": [ { "database": "UniProtKB", "id": "G3N3U7", "url": "https://www.uniprot.org/uniprotkb/G3N3U7" } ], "common_name": "Bovine", "glygen_name": "Bovine", "reference_species": "Bos taurus [9913]" } ], "gene": [ { "name": "EIF4EBP3", "url": "https://www.uniprot.org/uniprotkb/G3N3U7", "locus": {} } ], "crossref": [ { "id": "G3N3U7", "url": "https://alphafold.ebi.ac.uk/entry/G3N3U7", "database": "AlphaFoldDB", "categories": [] }, { "id": "ENSBTAG00000052310", "url": 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[ "Protein" ] }, { "id": "G3N3U7-1", "url": "https://www.uniprot.org/uniprotkb/G3N3U7-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MVGRVRDRLRSASSAPATAFLLFPFAMPHPPAARFMGAGKGCPTATAARRGRAGGTLYAATPGGTRIIYDLKFLLECKNSPTARRPPCCLPQIPGVTAPPTAPPPKLEELTEQKETEEEIPDDEQFGMDI", "length": 130, "header": "tr|G3N3U7-1|G3N3U7_BOVIN Isoform 1 of Eukaryotic translation initiation factor 4E binding protein 3 OS=Bos taurus OX=9913 GN=EIF4EBP3 PE=3 SV=2 CANONICAL=G3N3U7-1" }, "isoforms": [ { "isoform_ac": "G3N3U7-1", "url": "https://www.uniprot.org/uniprotkb/G3N3U7/entry", "sequence": { "sequence": "MVGRVRDRLRSASSAPATAFLLFPFAMPHPPAARFMGAGKGCPTATAARRGRAGGTLYAATPGGTRIIYDLKFLLECKNSPTARRPPCCLPQIPGVTAPPTAPPPKLEELTEQKETEEEIPDDEQFGMDI", "length": 130, "header": "tr|G3N3U7-1|G3N3U7_BOVIN Isoform 1 of Eukaryotic translation initiation factor 4E binding protein 3 OS=Bos taurus OX=9913 GN=EIF4EBP3 PE=3 SV=2 CANONICAL=G3N3U7-1" }, "locus": { "chromosome": "7", "start_pos": 51723691, "end_pos": 51722065, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000064322.3", "url": "https://www.ensembl.org/id/ENSBTAT00000064322.3" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000056609.2", "url": "https://www.ensembl.org/id/ENSBTAP00000056609.2" } ] } } ], "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "other", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 61, "start_aa": "Thr", "end_pos": 61, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr61", "evidence": [ { "id": "", "database": "GlyGen", "url": "https://data.glygen.org/" } ], "filter_code": "000000000000000010000.00000000001000.0.01000" } ], "phosphorylation": [], "glycation": [], "keywords": [ "glycoprotein", "glycoprotein_predicted" ], "publication": [], "pathway": [], "orthologs": [], "go_annotation": { "categories": [ { "name": "Molecular Function", "total": 2, "go_terms": [ { "name": "eukaryotic initiation factor 4E binding", "id": "GO:0008190", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008190", "evidence": [ { "database": "UniProtKB", "id": "G3N3U7", "url": "https://www.uniprot.org/uniprotkb/G3N3U7" } ], "pmid": "" }, { "name": "translation repressor activity", "id": "GO:0030371", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030371", "evidence": [ { "database": "UniProtKB", "id": "G3N3U7", "url": "https://www.uniprot.org/uniprotkb/G3N3U7" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 1, "go_terms": [ { "name": "negative regulation of translational initiation", "id": "GO:0045947", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0045947", "evidence": [ { "database": "UniProtKB", "id": "G3N3U7", "url": "https://www.uniprot.org/uniprotkb/G3N3U7" } ], "pmid": "" } ] } ] }, "pro_annotation": 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"count": 0 } ], "sort_fields": [] } ], "tool_support": { "graph_view": "yes" } }, { "uniprot_canonical_ac": "G3N329-1", "uniprot_ac": "G3N329", "uniprot_id": "G3N329_BOVIN", "mass": { "chemical_mass": 50415.0, "monoisotopic_mass": 50415.0 }, "refseq": {}, "gene_names": [ { "name": "INSYN2A", "type": "recommended", "evidence": [ { "id": "G3N329", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3N329" } ] } ], "protein_names": [ { "name": "Inhibitory synaptic factor 2A", "type": "synonym", "evidence": [ { "id": "G3N329", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3N329/entry#names_and_taxonomy" } ] } ], "function": [], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Bos taurus", "taxid": 9913, "evidence": [ { "database": "UniProtKB", "id": "G3N329", "url": "https://www.uniprot.org/uniprotkb/G3N329" } ], "common_name": "Bovine", "glygen_name": "Bovine", "reference_species": 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Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "F1MBD8", "url": "https://www.orthodb.org/?gene=F1MBD8", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR28682", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR28682", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR28682:SF1", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR28682:SF1", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF15265", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF15265", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "A0A3Q1MHN6", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1MHN6", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A3Q1MHN6-1", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1MHN6-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0AAA9S1A4", "url": 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"UniProtKB", "categories": [ "Protein" ] }, { "id": "G3N329", "url": "https://www.uniprot.org/uniprotkb/G3N329", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "G3N329-1", "url": "https://www.uniprot.org/uniprotkb/G3N329-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MVSKEPSKCVLTTSASEVEPAACLALEMKYALDPNRQIKKRNKALQVRFKDICEAQNEQRDTQLASGLQGDKREARPASCRAAYRKYMTVPARRSIPNVTKSTGVQTSPDLKKCYQTFPLDRKKGTLKSIPGTEAFKSQNNGLVIDAKEKSQEGPGEEARPWGAGRVQKTTALVFHSDEHVNALGPPTGVNCAEPCKTPDRHSYRDAPVQNSTRLSSQELEYQLLGKARQGRATPDTEEPAPSAHRRVFKTEVATVYAPAPGARAPAPALSNSAPSSEWSLCPAADLERRTAAQASGLQARPVVAPACSPPTQCLSPECSEEDASLQTQAPSGQERQPCPQALAADEECRQIVPHTEVVDLKAQLQMMENLISSSQETIKVLLGVIQELEKGEAHREGVELDFKQQEDKLQPVLRKLHPFEETQVAPSPYTQETYSSTPKQKSKTESKKHGRWKLWFL", "length": 458, "header": "tr|G3N329-1|G3N329_BOVIN Isoform 1 of Inhibitory synaptic factor 2A OS=Bos taurus OX=9913 GN=INSYN2A PE=4 SV=2 CANONICAL=G3N329-1" }, "isoforms": [ { "isoform_ac": "A0A3Q1MHN6-1", "url": 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"ENSBTAP00000070751.2", "url": "https://www.ensembl.org/id/ENSBTAP00000070751.2" } ] } }, { "isoform_ac": "A0AAA9S1A4-1", "url": "https://www.uniprot.org/uniprotkb/A0AAA9S1A4/entry", "sequence": { "sequence": "MVSKEPSKCVLTTSASEVEPAACLALEMKYALDPNRQIKKRNKALQVRFKDICEAQNEQRDTQLASGLQGDKREARPASCRAAYRKYMTVPARRSIPNVTKSTGVQTSPDLKKCYQTFPLDRKKGTLKSIPGTEAFKSQNNGLVIDAKEKSQEGPGEEARPWGAGRVQKTTALVFHSDEHVNALGPPTGVNCAEPCKTPDRHSYRDAPVQNSTRLSSQELEYQLLGKARQGRATPDTEEPAPSAHRRVFKTEVATVYAPAPGARAPAPALSNSAPSSEWSLCPAADLERRTAAQASGLQARPVVAPACSPPTQCLSPECSEEDASLQTQAPSGQERQPCPQALAADEECRQIVPHTEVVDLKAQLQMMENLISSSQETIKVLLGVIQELEKGEAHREGLSYRTGQDTANCDTCRNSACIIYSVELDFKQQEDKLQPVLRKLHPFEETQVAPSPYTQETYSSTPKQKSKTESKKHGRWKLWFL", "length": 482, "header": "tr|A0AAA9S1A4-1|G3N329_BOVIN Computationally mapped isoform of Inhibitory synaptic factor 2A OS=Bos taurus OX=9913 GN=INSYN2A PE=4 SV=1 CANONICAL=G3N329-1" }, "locus": { "chromosome": "26", "start_pos": 46654865, "end_pos": 46616327, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000098562.1", "url": "https://www.ensembl.org/id/ENSBTAT00000098562.1" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000075868.1", "url": "https://www.ensembl.org/id/ENSBTAP00000075868.1" } ] } }, { "isoform_ac": "A0AAA9SNK0-1", "url": "https://www.uniprot.org/uniprotkb/A0AAA9SNK0/entry", "sequence": { "sequence": "MVSKEPSKCVLTTSASEVEPAACLALEMKYALDPNRQIKKRNKALQVRFKDICEAQNEQRDTQLASGLQGDKREARPASCRAAYRKYMTVPARRSIPNVTKSTGVQTSPDLKKCYQTFPLDRKKGTLKSIPGTEAFKSQNNGLVIDAKEKSQEGPGEEARPWGAGRVQKTTALVFHSDEHVNALGPPTGVNCAEPCKTPDRHSYRDAPVQNSTRLSSQELEYQLLGKARQGRATPDTEEPAPSAHRRVFKTEVATVYAPAPGARAPAPALSNSAPSSEWSLCPAADLERRTAAQASGLQARPVVAPACSPPTQCLSPECSEEDASLQTQAPSGQERQPCPQALAADEECRQIVPHTEVVDLKAQLQMMENLISSSQETIKVLLGVIQELEKGEAHREGLSYRTGQDTANCDTCRNSACIIYRLCQSFEVRTRCLLCLWSPQLDFRVICHEPHPLPCSGTWS", "length": 461, "header": "tr|A0AAA9SNK0-1|G3N329_BOVIN Computationally mapped isoform of Inhibitory synaptic factor 2A OS=Bos taurus OX=9913 GN=INSYN2A PE=4 SV=1 CANONICAL=G3N329-1" }, "locus": { "chromosome": "26", "start_pos": 46654865, "end_pos": 46628801, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000097267.1", "url": "https://www.ensembl.org/id/ENSBTAT00000097267.1" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000087905.1", "url": "https://www.ensembl.org/id/ENSBTAP00000087905.1" } ] } }, { "isoform_ac": "A0AAA9TRL3-1", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TRL3/entry", "sequence": { "sequence": "MVSKEPSKCVLTTSASEVEPAACLALEMKYALDPNRQIKKRNKALQVRFKDICEAQNEQRDTQLASGLQGDKREARPASCRAAYRKYMTVPARRSIPNVTKSTGVQTSPDLKKCYQTFPLDRKKGTLKSIPGTEAFKSQNNGLVIDAKEKSQEGPGEEARPWGAGRVQKTTALVFHSDEHVNALGPPTGVNCAEPCKTPDRHSYRDAPVQNSTRLSSQELEYQLLGKARQGRATPDTEEPAPSAHRRVFKTEVATVYAPAPGARAPAPALSNSAPSSEWSLCPAADLERRTAAQASGLQARPVVAPACSPPTQCLSPECSEEDASLQTQAPSGQERQPCPQALAADEECRQIVPHTEVVDLKAQLQMMENLISSSQETIKVLLGVIQELEKGEAHREGLTQWRRKWQPTPEFLPAESQGWQSLVGCYLWGRTESDTTEAT", "length": 440, "header": "tr|A0AAA9TRL3-1|G3N329_BOVIN Computationally mapped isoform of Inhibitory synaptic factor 2A OS=Bos taurus OX=9913 GN=INSYN2A PE=4 SV=1 CANONICAL=G3N329-1" }, "locus": { "chromosome": "26", "start_pos": 46654865, "end_pos": 46646934, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000129791.1", "url": "https://www.ensembl.org/id/ENSBTAT00000129791.1" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000101220.1", "url": "https://www.ensembl.org/id/ENSBTAP00000101220.1" } ] } }, { "isoform_ac": "F1MBD8-1", "url": "https://www.uniprot.org/uniprotkb/F1MBD8/entry", "sequence": { "sequence": "MVSKEPSKCVLTTSASEVEPAACLALEMKYALDPNRQIKKRNKALQVRFKDICEAQNEQRDTQLASGLQGDKREARPASCRAAYRKYMTVPARRSIPNVTKSTGVQTSPDLKKCYQTFPLDRKKGTLKSIPGTEAFKSQNNGLVIDAKEKSQEGPGEEARPWGAGRVQKTTALVFHSDEHVNALGPPTGVNCAEPCKTPDRHSYRDAPVQNSTRLSSQELEYQLLGKARQGRATPDTEEPAPSAHRRVFKTEVATVYAPAPGARAPAPALSNSAPSSEWSLCPAADLERRTAAQASGLQARPVVAPACSPPTQCLSPECSEEDASLQTQAPSGQERQPCPQALAADEECRQIVPHTEVVDLKAQLQMMENLISSSQETIKVLLGVIQELEKGEAHREGLSYRTGQDTANCDTCRNSACIIYSTGRQILYHRAAGRPNRVINKNKIF", "length": 446, "header": "tr|F1MBD8-1|G3N329_BOVIN Computationally mapped isoform of Inhibitory synaptic factor 2A OS=Bos taurus OX=9913 GN=INSYN2A PE=4 SV=4 CANONICAL=G3N329-1" }, "locus": { "chromosome": "26", "start_pos": 46654865, "end_pos": 46629310, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000027987.6", "url": "https://www.ensembl.org/id/ENSBTAT00000027987.6" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000027987.6", "url": "https://www.ensembl.org/id/ENSBTAP00000027987.6" } ] } }, { "isoform_ac": "G3N329-1", "url": "https://www.uniprot.org/uniprotkb/G3N329/entry", "sequence": { "sequence": "MVSKEPSKCVLTTSASEVEPAACLALEMKYALDPNRQIKKRNKALQVRFKDICEAQNEQRDTQLASGLQGDKREARPASCRAAYRKYMTVPARRSIPNVTKSTGVQTSPDLKKCYQTFPLDRKKGTLKSIPGTEAFKSQNNGLVIDAKEKSQEGPGEEARPWGAGRVQKTTALVFHSDEHVNALGPPTGVNCAEPCKTPDRHSYRDAPVQNSTRLSSQELEYQLLGKARQGRATPDTEEPAPSAHRRVFKTEVATVYAPAPGARAPAPALSNSAPSSEWSLCPAADLERRTAAQASGLQARPVVAPACSPPTQCLSPECSEEDASLQTQAPSGQERQPCPQALAADEECRQIVPHTEVVDLKAQLQMMENLISSSQETIKVLLGVIQELEKGEAHREGVELDFKQQEDKLQPVLRKLHPFEETQVAPSPYTQETYSSTPKQKSKTESKKHGRWKLWFL", "length": 458, "header": "tr|G3N329-1|G3N329_BOVIN Isoform 1 of Inhibitory synaptic factor 2A OS=Bos taurus OX=9913 GN=INSYN2A PE=4 SV=2 CANONICAL=G3N329-1" }, "locus": { "chromosome": "26", "start_pos": 46654865, "end_pos": 46616327, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000064269.3", "url": "https://www.ensembl.org/id/ENSBTAT00000064269.3" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000056301.2", "url": "https://www.ensembl.org/id/ENSBTAP00000056301.2" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [ { "id": "bta:784700", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?bta:784700", "resource": "KEGG Pathway" } ], "orthologs": [], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 1, "go_terms": [ { "name": "postsynaptic density", "id": "GO:0014069", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0014069", "evidence": [ { "database": "UniProtKB", "id": "G3N329", "url": "https://www.uniprot.org/uniprotkb/G3N329" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 1, "go_terms": [ { "name": "inhibitory postsynaptic potential", "id": "GO:0060080", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0060080", "evidence": [ { "database": "UniProtKB", "id": "G3N329", "url": "https://www.uniprot.org/uniprotkb/G3N329" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 211, "end_pos": 213, "annotation": "n_glycosylation_sequon" }, { "start_pos": 98, "end_pos": 100, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 211, "end_pos": 213 }, { "start_pos": 98, "end_pos": 100 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ], "tool_support": { "graph_view": "yes" } }, { "uniprot_canonical_ac": "G3MX93-1", "uniprot_ac": "G3MX93", "uniprot_id": "G3MX93_BOVIN", "mass": { "chemical_mass": 71579.0, "monoisotopic_mass": 71579.0 }, "refseq": {}, "gene_names": [ { "name": "LMNTD2", "type": "recommended", "evidence": [ { "id": "G3MX93", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3MX93" } ] } ], "protein_names": [ { "name": "Lamin tail domain containing 2", "type": "synonym", "evidence": [ { "id": "G3MX93", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3MX93/entry#names_and_taxonomy" } ] } ], "function": [], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Bos taurus", "taxid": 9913, "evidence": [ { "database": "UniProtKB", "id": "G3MX93", "url": "https://www.uniprot.org/uniprotkb/G3MX93" } ], "common_name": "Bovine", "glygen_name": "Bovine", "reference_species": "Bos taurus [9913]" } ], "gene": [ { "name": "LMNTD2", "url": "https://www.uniprot.org/uniprotkb/G3MX93", "locus": { "chromosome": "29", "start_pos": 50744918, "end_pos": 50739784, "strand": "-", "evidence": [ { "database": "Ensembl Gene", "id": "ENSBTAG00000047713", "url": "https://www.ensembl.org/id/ENSBTAG00000047713" } ] } } ], "crossref": [ { "id": "G3MX93", "url": "https://alphafold.ebi.ac.uk/entry/G3MX93", "database": "AlphaFoldDB", "categories": [] }, { "id": "ENSBTAG00000047713", "url": "https://bgee.org/?page=gene&gene_id=ENSBTAG00000047713", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "cd22265", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd22265", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "IPR001322", "url": "https://www.ebi.ac.uk/interpro/entry/IPR001322", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR036415", "url": "https://www.ebi.ac.uk/interpro/entry/IPR036415", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR052877", "url": "https://www.ebi.ac.uk/interpro/entry/IPR052877", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "HLTVWGE", "url": "https://omabrowser.org/oma/group/HLTVWGE/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "PTHR19956", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR19956", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR19956:SF5", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR19956:SF5", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "A0A3Q1MJ14", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1MJ14", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A3Q1MJ14-1", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1MJ14-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "G3MX93", "url": "https://www.uniprot.org/uniprotkb/G3MX93", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "G3MX93-1", "url": "https://www.uniprot.org/uniprotkb/G3MX93-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MAPKSCQEAEDAEEEALASLVDREPVSGHMGPPVGAAADPVASTHPQNAKPSSTRMVSSINLSALESLDPRTLRLLWGQRELEIQALRWAIQNQREARHCRILQEVAGLPAERSSRSKDKFLQNQVQKLTLELKAQKEKAQLQEKKRLEERLQQAEDALRQLEAELQAFQKSCLLQLARSSWVGRVLRSSTGSVEVVTAETLMDLSDFSENDQAPTAGEGFRLEDVDWNSIAHRYPNLFTNLESSSDQKHPRTSQLPTASPPDQWSSELCCRHQEHNLKSVEWSSLPLAGTSSSGGADSESSNSQLAAHNRVHKVTGDPPQVPSHTAKQVEARAQSLCRDSQSPCLHSSPSPSGSCLKIMAVSRRQRFVRILNQSLEETVDLGGFVLQQLVLDFPVCMYRFPPSTLLPPRHHITVWGEGPCSTRRQQLSSLGREPVHFYSSRSCVTLLLNPQGEVLSEHQSPHCVTPVSRIFADNTDLSIDCFPLSEARPEADLAEHQPQPRPPRKGRVREARAGRRRPGWGPRVLQCRVCPGTTPSRWQAVSHDPSLARPRVQLPRLSTIKLLRQREAPVWPEDVAQTHPELLPSIPIPGESASRAPPPQVCRKRVDCGCPMVALSVQSTAESRFGFRFLSCPPITVDTRWPL", "length": 644, "header": "tr|G3MX93-1|G3MX93_BOVIN Isoform 1 of Lamin tail domain containing 2 OS=Bos taurus OX=9913 GN=LMNTD2 PE=4 SV=3 CANONICAL=G3MX93-1" }, "isoforms": [ { "isoform_ac": "A0A3Q1MJ14-1", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1MJ14/entry", "sequence": { "sequence": "MAPKSCQEAEDAEEEALASLVDREPVSGHMGPPVGAAADPVASTHPQNAKPSSTRMVSSINLSALESLDPRTLRLLWGQRELEIQALRWAIQNQREARHCRILQEVAGLPAERSSRSKDKFLQNQVQKLTLELKAQKEKAQLEKKRLEERLQQAEDALRQLEAELQAFQKSCLLQLARSSWVGRVLRSSTGSVEVVTAETLMDLSDFSENDQAPTAGEGFRLEDVDWNSIAHRYPNLFTNLESSSDQKHPRTSQLPTASPPDQWSSELCCRHQEHNLKSVEWSSLPLAGTSSSGGADSESSNSQLAAHNRVHKVTGDPPQVPSHTAKQVEARAQSLSRLSVHLQKTHSDEQGKNGPEPDPCLHSSPSPSGSCLKIMAVSRRQRFVRILNQSLEETVDLGGFVLQQLVLDFPVCMYRFPPSTLLPPRHHITVWGEGPCSTRRQQLSSLGREPVHFYSSRSCVTLLLNPQGEVLSEHQSPHCVTPVSRIFADNTDLSIDCFPLSEARPEADLAEHQPQPRPPRKGRVREARAGRRRPGWGPRVLQCLLPPQVLSAQLGGTWRRGGRQGGGARPTPPILFPAEVGVGLQDCQGRKDHKIRVCRKRVDCGCPMVALSVQSTAESRFGFRFLSCPPITVDTRWPL", "length": 640, "header": "tr|A0A3Q1MJ14-1|G3MX93_BOVIN Computationally mapped isoform of Lamin tail domain containing 2 OS=Bos taurus OX=9913 GN=LMNTD2 PE=4 SV=1 CANONICAL=G3MX93-1" }, "locus": { "chromosome": "29", "start_pos": 50744600, "end_pos": 50739784, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000070913.3", "url": "https://www.ensembl.org/id/ENSBTAT00000070913.3" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000069178.1", "url": "https://www.ensembl.org/id/ENSBTAP00000069178.1" } ] } }, { "isoform_ac": "G3MX93-1", "url": "https://www.uniprot.org/uniprotkb/G3MX93/entry", "sequence": { "sequence": "MAPKSCQEAEDAEEEALASLVDREPVSGHMGPPVGAAADPVASTHPQNAKPSSTRMVSSINLSALESLDPRTLRLLWGQRELEIQALRWAIQNQREARHCRILQEVAGLPAERSSRSKDKFLQNQVQKLTLELKAQKEKAQLQEKKRLEERLQQAEDALRQLEAELQAFQKSCLLQLARSSWVGRVLRSSTGSVEVVTAETLMDLSDFSENDQAPTAGEGFRLEDVDWNSIAHRYPNLFTNLESSSDQKHPRTSQLPTASPPDQWSSELCCRHQEHNLKSVEWSSLPLAGTSSSGGADSESSNSQLAAHNRVHKVTGDPPQVPSHTAKQVEARAQSLCRDSQSPCLHSSPSPSGSCLKIMAVSRRQRFVRILNQSLEETVDLGGFVLQQLVLDFPVCMYRFPPSTLLPPRHHITVWGEGPCSTRRQQLSSLGREPVHFYSSRSCVTLLLNPQGEVLSEHQSPHCVTPVSRIFADNTDLSIDCFPLSEARPEADLAEHQPQPRPPRKGRVREARAGRRRPGWGPRVLQCRVCPGTTPSRWQAVSHDPSLARPRVQLPRLSTIKLLRQREAPVWPEDVAQTHPELLPSIPIPGESASRAPPPQVCRKRVDCGCPMVALSVQSTAESRFGFRFLSCPPITVDTRWPL", "length": 644, "header": "tr|G3MX93-1|G3MX93_BOVIN Isoform 1 of Lamin tail domain containing 2 OS=Bos taurus OX=9913 GN=LMNTD2 PE=4 SV=3 CANONICAL=G3MX93-1" }, "locus": { "chromosome": "29", "start_pos": 50744600, "end_pos": 50739784, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000064081.3", "url": "https://www.ensembl.org/id/ENSBTAT00000064081.3" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000054154.3", "url": "https://www.ensembl.org/id/ENSBTAP00000054154.3" } ] } } ], "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "other", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 535, "start_aa": "Thr", "end_pos": 535, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr535", "evidence": [ { "id": "", "database": "GlyGen", "url": "https://data.glygen.org/" } ], "filter_code": "000000000000000010000.00000000001000.0.01000" } ], "phosphorylation": [], "glycation": [], "keywords": [ "glycoprotein", "glycoprotein_predicted" ], "publication": [], "pathway": [], "orthologs": [ { "uniprot_canonical_ac": "A0A061IDR1-1", "protein_name": "Lamin tail domain-containing protein 2", "gene_name": "Lmntd2", "tax_id": 10029, "organism": "Cricetulus griseus", "sequence": { "sequence": "MAPKSCQESEDEQVSPAPSGVKPDSRELESPGGTPLDTVAPSSSQSSKPYCASTPVGCSAKQQLSPETLDPCTLRLLWEQRELEIQALRWAVQNDQNARYYHILQEVAGIPPERNSKSQDKILQNQVQKLTLELKAQKEQAQLEKESLEEKLQQNLCAIQQLEAELQTFQKSCLLQLARSSWVGRMLRSQTGSVEVVTAEVLKDPSDSSEYAEVPTAGEGFRLEDVDWNSIAHRYPNLFSNMSYHSDHKLPQPQQSSEMDASDSESVKHVEKPGKSLEWSALPVVDNSSSEGTDSDYSSCQLVLHSGGKVVTGHSPQGTDLTSEQMQESTRSGSGHMEDLHKSRSPSDSKTVLEPFADLHLQYARPQLNPLGCCLKIAAVSYRERFIRILNQSQAETVDLGGFVLRQFVKDFPVCMYRFPPGTLLAPQHHITVWGEGASRTKKHLPVSSGQDPFHFQSSRGCVTMLVNPHGQVLSEHQAAPCVTLGSKIFTDNTDWSIDRFPLPESEPNADHGEERHRPSSPHKGRVQYARAMRKKPGPGVHQQRTSGLRTSGSLRPTETRDILPLLSTRKLLHLGEVPAQQEGMKTETSELLPAIPECPSRVCLEDSQGRQERKVQVCRKSVDLSCPMVALSVQNSAESRYGFRFLCYPPITEELFRRL", "length": 660 }, "evidence": [ { "id": "G3MX93", "url": "https://omabrowser.org/oma/group/G3MX93/", "database": "OMA" } ], "glygen_name": "Hamster", "common_name": "Chinese hamster" }, { "uniprot_canonical_ac": "Q0VET5-1", "protein_name": "Lamin tail domain-containing protein 2", "gene_name": "Lmntd2", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MAPKSCQESEDKQVSPAPAGVQPDSSDLGSPVGTPVDRVAPSYSQSAKLYTSTPMGCSVKQQLAPETLDPRTLRLLWEQRELEIQALRWAVQNGHNARYSSILQEVAGVPSERNSKSQDKFLRNQVQKLTLELKAQKEQAQQEKQQLEEKLQQNLWAKQQLEAELQTFQKSCLLQLARSSWVGRVLRSQTGSVEVVTTEVLRDPSDFSESAEIPTSGEGFPLEDVDWNSIAQRYPNLFSNLNFYSDQKQSQPPTSETYTLDSEGATKHTEKPTKILEWSALPLLDTSSSERTQSDTSSCPIALHSGAKKTTGHPSQGTNLASSEQMQEHTRSFSGYTEDLCKSHSPSCSKTVLESYTDLHHPYTRPQLNPFGCCLKIAAVSHREKFIRVINQSQAETIDLGGFVLQQLVRDFPVCMYRFPPGTLLAPQHHITVWGEGTSRTKKQLPVASGQDPFQFQSSRGCVTVLVNPQGQVLSEHQATPCVTLGSKIFTDNTDWSIDCFPLSESEPDVHPGEQQCRPSSPQKGRAKDAGARRKKPGPGVRQHRHSSTSGLRASRTLHPTETRDILPLLSSRKLLPSGEVLTQQEGVKAETSELLPVIPECPSRLCLGEDSLGRQEYKVQVCRKSVDLSCPMVALSVQNTAESRYGFRFLCYPPITEELCRRL", "length": 664 }, "evidence": [ { "id": "G3MX93", "url": "https://omabrowser.org/oma/group/G3MX93/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q8IXW0-1", "protein_name": "Lamin tail domain-containing protein 2", "gene_name": "LMNTD2", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MRWLRPAGRRREQESVSGHLGPPAGAPAAPETPTCLPDTTPHPAPVVCSADPQLALESLDPRTLRLLWRQRELEIQALRWAIQNGEDARLCHILEEVAGLPPKRSSHSQEKLLQNQVQKLIQELKEQKERAQWEKEHLEERLLQTTRTLQEMEAELQNLQKSCLLQLARSSWVGRMLRSQTGSVEVVTAETLMDPSDLSENIQAPTGEGFRLEDVDWNSVARRYPNLFTNMEPSSKQKQPRPWPQLDTGSPESSGKHSERHHKTVEWGSLPCLNTSSSGGADSDSSSCRPGLPSFVQVIGHPPRDHRASSEQALVQAGSYSRDSEDLQKTHSPRHGEPVLSPQPCTDPDHWSPELLQSPTGLKIVAVSCREKFVRIFNPSQESTADLSGMVLKQLVRGFPERLYRFPPGTLLAPRHHVTVWGEATRSAKKPLRASSSREPVPLLSIRGCATLLLSPKGEVLSEHRIPRRETPAPRVFADGTDLSIDRFPLPEAGPGADTRKPPRPPRPLRKGRVREPRVSRRRPGTRGLLPPVSSGKLFHAREGPARPENPEIPAPQHLPAIPGDPTLPSPPAEAGLGLEDCRLQKEHRVRVCRKSVDRSCPLVALSVQNTAESRFGFRFLSCLPVTADTCRGA", "length": 634 }, "evidence": [ { "id": "G3MX93", "url": "https://omabrowser.org/oma/group/G3MX93/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" } ], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 1, "go_terms": [ { "name": "lamin filament", "id": "GO:0005638", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005638", "evidence": [ { "database": "UniProtKB", "id": "G3MX93", "url": "https://www.uniprot.org/uniprotkb/G3MX93" } ], "pmid": "" } ] }, { "name": "Molecular Function", "total": 1, "go_terms": [ { "name": "structural constituent of chromatin", "id": "GO:0030527", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030527", "evidence": [ { "database": "UniProtKB", "id": "G3MX93", "url": "https://www.uniprot.org/uniprotkb/G3MX93" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 373, "end_pos": 375, "annotation": "n_glycosylation_sequon" }, { "start_pos": 61, "end_pos": 63, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [ { "pdb_id": "AF-G3MX93-F1", "pdb_chain": "global", "start_pos": 1, "end_pos": 644, "overlap": "1.0", "method": "AlphaFold", "type": "alphafold", "resolution": -1.0, "url": "https://data.glygen.org/ln2downloads/pdb/current/AF-G3MX93-F1.pdb", "url_external": "https://alphafold.ebi.ac.uk/entry/G3MX93" } ], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "G3MX93", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3MX93" }, { "id": "PS51841", "database": "PROSITE", "url": "https://prosite.expasy.org/PS51841" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "LTD", "eco_id": "ECO_0000259", "start_pos": 344, "end_pos": 463, "start_aa": "Pro", "end_aa": "His", "glycosite_overlap": [] } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" }, { "name": "homologset.oma", "label": "OMA Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [ 535 ], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 373, "end_pos": 375 }, { "start_pos": 61, "end_pos": 63 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 1 }, { "field": "total_sites", "count": 1 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 1 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "exact_sites", "count": 1 }, { "field": "exact_o_linked_sites", "count": 1 }, { "field": "fuzzy_sites", "count": 0 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_pos", "start_aa", "end_pos", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 1 }, { "field": "total_sites", "count": 1 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 1 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "exact_sites", "count": 1 }, { "field": "exact_o_linked_sites", "count": 1 }, { "field": "fuzzy_sites", "count": 0 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_pos", "start_aa", "end_pos", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ], "tool_support": { "graph_view": "yes" } }, { "uniprot_canonical_ac": "G3N3U8-1", "uniprot_ac": "G3N3U8", "uniprot_id": "G3N3U8_BOVIN", "mass": { "chemical_mass": 36079.0, "monoisotopic_mass": 36079.0 }, "refseq": { "ac": "XP_005210817", "name": "calcium homeostasis modulator protein 5 isoform X1", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_005210817" }, "gene_names": [ { "name": "CALHM5", "type": "recommended", "evidence": [ { "id": "G3N3U8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3N3U8" } ] }, { "name": "CALHM5", "type": "synonym", "evidence": [ { "id": "XP_005210817", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_005210817" } ] } ], "protein_names": [ { "name": "Calcium homeostasis modulator family member 5", "type": "synonym", "evidence": [ { "id": "G3N3U8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3N3U8/entry#names_and_taxonomy" } ] }, { "name": "calcium homeostasis modulator protein 5 isoform X1", "type": "synonym", "evidence": [ { "id": "XP_005210817", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_005210817" } ] } ], "function": [], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Bos taurus", "taxid": 9913, "evidence": [ { "database": "UniProtKB", "id": "G3N3U8", "url": "https://www.uniprot.org/uniprotkb/G3N3U8" } ], "common_name": "Bovine", "glygen_name": "Bovine", "reference_species": "Bos taurus [9913]" } ], "gene": [ { "name": "CALHM5", "url": "https://www.uniprot.org/uniprotkb/G3N3U8", "locus": { "chromosome": "9", "start_pos": 34208953, "end_pos": 34214412, "strand": "+", "evidence": [ { "database": "Ensembl Gene", "id": "ENSBTAG00000045879", "url": "https://www.ensembl.org/id/ENSBTAG00000045879" } ] } } ], "crossref": [ { "id": "G3N3U8", "url": "https://alphafold.ebi.ac.uk/entry/G3N3U8", "database": "AlphaFoldDB", "categories": [] }, { "id": "ENSBTAG00000045879", "url": "https://bgee.org/?page=gene&gene_id=ENSBTAG00000045879", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "101903708", "url": "https://www.ncbi.nlm.nih.gov/gene/101903708", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR029569", "url": "https://www.ebi.ac.uk/interpro/entry/IPR029569", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "bta:101903708", "url": "https://www.genome.jp/dbget-bin/www_bget?bta:101903708", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "HYSTIHR", "url": "https://omabrowser.org/oma/group/HYSTIHR/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "A0A3Q1MMJ7", "url": "https://www.orthodb.org/?gene=A0A3Q1MMJ7", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "G3N3U8", "url": "https://www.orthodb.org/?gene=G3N3U8", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR32261", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR32261", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR32261:SF8", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR32261:SF8", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF14798", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF14798", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "XP_005210817", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_005210817", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A3Q1MMJ7", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1MMJ7", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A3Q1MMJ7-1", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1MMJ7-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "G3N3U8", "url": "https://www.uniprot.org/uniprotkb/G3N3U8", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "G3N3U8-1", "url": "https://www.uniprot.org/uniprotkb/G3N3U8-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MDALQGFLKFILNQKTFIGYSFMALLTVGGERLFSLVAFKCPCGTENVIYGLAFLFAPAWVLLILGFFLNNRSWRLFTGCCVNPRKIFPRGHNCRFFSVLGQIILSSLVAPVMWLSVALLNGTFYECAMSGTQSPRLLDLICKGKPEECWKELYKVSCGKTSMTPTDNEELKLSLQAQSQILGWFLICSASFFSLLTTCYARCRSKVSYLQLSFWKTYAQKEKEQLENTFVDYAKKLSDRNLKCFLENKRPDVFPMPTFAAWEAASELHSFHQNRQHYSTLHRVVEEGLDLRPEDEETTMMLMGTAQNVQLTHHH", "length": 315, "header": "tr|G3N3U8-1|G3N3U8_BOVIN Isoform 1 of Calcium homeostasis modulator family member 5 OS=Bos taurus OX=9913 GN=CALHM5 PE=3 SV=2 CANONICAL=G3N3U8-1" }, "isoforms": [ { "isoform_ac": "A0A3Q1MMJ7-1", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1MMJ7/entry", "sequence": { "sequence": "MKKELHPRPLPQRLCQQVRAKHFPSVYLQHGCSSGVSKIHPQPENFHWLQLHGSADRGRSWRLFTGCCVNPRKIFPRGHNCRFFSVLGQIILSSLVAPVMWLSVALLNGTFYECAMSGTQSPRLLDLICKGKPEECWKELYKVSCGKTSMTPTDNEELKLSLQAQSQILGWFLICSASFFSLLTTCYARCRSKVSYLQLSFWKTYAQKEKEQLENTFVDYAKKLSDRNLKCFLENKRPDVFPMPTFAAWEAASELHSFHQNRQHYSTLHRVVEEGLDLRPEDEETTMMLMGTAQNVQLTHHH", "length": 302, "header": "tr|A0A3Q1MMJ7-1|G3N3U8_BOVIN Computationally mapped isoform of Calcium homeostasis modulator family member 5 OS=Bos taurus OX=9913 GN=CALHM5 PE=3 SV=1 CANONICAL=G3N3U8-1" }, "locus": { "chromosome": "9", "start_pos": 34214359, "end_pos": 34209957, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000072397.2", "url": "https://www.ensembl.org/id/ENSBTAT00000072397.2" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000070648.1", "url": "https://www.ensembl.org/id/ENSBTAP00000070648.1" } ] } }, { "isoform_ac": "G3N3U8-1", "url": "https://www.uniprot.org/uniprotkb/G3N3U8/entry", "sequence": { "sequence": "MDALQGFLKFILNQKTFIGYSFMALLTVGGERLFSLVAFKCPCGTENVIYGLAFLFAPAWVLLILGFFLNNRSWRLFTGCCVNPRKIFPRGHNCRFFSVLGQIILSSLVAPVMWLSVALLNGTFYECAMSGTQSPRLLDLICKGKPEECWKELYKVSCGKTSMTPTDNEELKLSLQAQSQILGWFLICSASFFSLLTTCYARCRSKVSYLQLSFWKTYAQKEKEQLENTFVDYAKKLSDRNLKCFLENKRPDVFPMPTFAAWEAASELHSFHQNRQHYSTLHRVVEEGLDLRPEDEETTMMLMGTAQNVQLTHHH", "length": 315, "header": "tr|G3N3U8-1|G3N3U8_BOVIN Isoform 1 of Calcium homeostasis modulator family member 5 OS=Bos taurus OX=9913 GN=CALHM5 PE=3 SV=2 CANONICAL=G3N3U8-1" }, "locus": { "chromosome": "9", "start_pos": 34214271, "end_pos": 34209957, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000063525.3", "url": "https://www.ensembl.org/id/ENSBTAT00000063525.3" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000056611.2", "url": "https://www.ensembl.org/id/ENSBTAP00000056611.2" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [ { "id": "bta:101903708", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?bta:101903708", "resource": "KEGG Pathway" } ], "orthologs": [ { "uniprot_canonical_ac": "G3HJW1-1", "protein_name": "Calcium homeostasis modulator protein 5", "gene_name": "Calhm5", "tax_id": 10029, "organism": "Cricetulus griseus", "sequence": { "sequence": "MDAFQSILKFFLNQRTAIGYSFMALLTVGSERLFSLVAFKCPCSAENTAYGLVFLFAPAWVLLILGFFLNNKAWRLFTGCCINPRKIFRRRRCCRFFYVLGHITLSSLVAPVMWLSVALLNGTFYECAMSGTRSTRLLELICRGKPKECWEELYKVSCGRSSMAPTDNEEVKLSLQAQSQILGWCLICSASFFSLLTTCYARCKSKVSYLQLSFWKTYAQREKEQLENKLLECANKLSERNLKCFFENKKPDPFPMPSFAAWEAASELHSFYHDREYYSALHKVIDNGLEQTPQEEETEMILVGSAQSL", "length": 309 }, "evidence": [ { "id": "G3N3U8", "url": "https://omabrowser.org/oma/group/G3N3U8/", "database": "OMA" } ], "glygen_name": "Hamster", "common_name": "Chinese hamster" }, { "uniprot_canonical_ac": "Q5FWS4-1", "protein_name": "Calcium homeostasis modulator protein 5", "gene_name": "Calhm5", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MDAFQSILKFFLNQKTAIGYSFMALLTVGSERLFSLVAFKCPCSIENTAYGLVFLFAPAWVLLILGFFLNNKAWRLFTGCCMNPQKIFPRRRCCRFFYVLGHITLSSLVAPVMWLSVALLNGTFYECAMSGTRSTRLLEMICKGKPKECWEELHKVSCGKSSMAAMDSEEVRLSLQAQSQILGWCLICSASFFSLLTTCYARCRSKVSYLQLSFWKTYAQREKEQLENKLLEYANKLSERNLKCFFENKKPDPFPMPSFAAWEAASELHSFHQDREHYSTLHKVVDDGLEQTPQEEETTMILVGTAQSL", "length": 309 }, "evidence": [ { "id": "G3N3U8", "url": "https://omabrowser.org/oma/group/G3N3U8/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "Q8N5C1-1", "protein_name": "Calcium homeostasis modulator protein 5", "gene_name": "CALHM5", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MDAFQGILKFFLNQKTVIGYSFMALLTVGSERLFSVVAFKCPCSTENMTYGLVFLFAPAWVLLILGFFLNNRSWRLFTGCCVNPRKIFPRGHSCRFFYVLGQITLSSLVAPVMWLSVALLNGTFYECAMSGTRSSGLLELICKGKPKECWEELHKVSCGKTSMLPTVNEELKLSLQAQSQILGWCLICSASFFSLLTTCYARCRSKVSYLQLSFWKTYAQKEKEQLENTFLDYANKLSERNLKCFFENKRPDPFPMPTFAAWEAASELHSFHQSQQHYSTLHRVVDNGLQLSPEDDETTMVLVGTAHNM", "length": 309 }, "evidence": [ { "id": "G3N3U8", "url": "https://omabrowser.org/oma/group/G3N3U8/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "Q8R100-1", "protein_name": "Calcium homeostasis modulator protein 5", "gene_name": "Calhm5", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MDAFQSILKFFLNQKTAIGYSFMALLTVGSERLFSLVAFKCPCSVENTAYGLVFLFAPAWVLLILGFFLNNKAWRLFTGCCMNPKKIFPRRRCCRFFYVLGHIILSSLVAPVMWLSVALLNGTFYECAMSGTRSTRLLEMICKGKPKECWEELHKVSCGKSSMAAMESEEVRLSLQAQSQILGWCLICSASFLSLLTTCYARCRSKVSYLQLSFWKTYAQREKEQLENKLLECANKLSERNLKCFFENKKPDPFPMPSFGAWEAASELHSFHQDREHYSTLHKVVDDGMEQTPQEEETTMILVGTAQSL", "length": 309 }, "evidence": [ { "id": "G3N3U8", "url": "https://omabrowser.org/oma/group/G3N3U8/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" } ], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 2, "go_terms": [ { "name": "membrane", "id": "GO:0016020", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016020", "evidence": [ { "database": "UniProtKB", "id": "G3N3U8", "url": "https://www.uniprot.org/uniprotkb/G3N3U8" } ], "pmid": "" }, { "name": "plasma membrane", "id": "GO:0005886", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005886", "evidence": [ { "database": "UniProtKB", "id": "G3N3U8", "url": "https://www.uniprot.org/uniprotkb/G3N3U8" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 2, "go_terms": [ { "name": "monoatomic ion transmembrane transport", "id": "GO:0034220", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0034220", "evidence": [ { "database": "UniProtKB", "id": "G3N3U8", "url": "https://www.uniprot.org/uniprotkb/G3N3U8" } ], "pmid": "" }, { "name": "ATP export", "id": "GO:1904669", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:1904669", "evidence": [ { "database": "UniProtKB", "id": "G3N3U8", "url": "https://www.uniprot.org/uniprotkb/G3N3U8" } ], "pmid": "" } ] }, { "name": "Molecular Function", "total": 1, "go_terms": [ { "name": "monoatomic cation channel activity", "id": "GO:0005261", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005261", "evidence": [ { "database": "UniProtKB", "id": "G3N3U8", "url": "https://www.uniprot.org/uniprotkb/G3N3U8" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 121, "end_pos": 123, "annotation": "n_glycosylation_sequon" }, { "start_pos": 71, "end_pos": 73, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [ { "pdb_id": "AF-G3N3U8-F1", "pdb_chain": "global", "start_pos": 1, "end_pos": 315, "overlap": "1.0", "method": "AlphaFold", "type": "alphafold", "resolution": -1.0, "url": "https://data.glygen.org/ln2downloads/pdb/current/AF-G3N3U8-F1.pdb", "url_external": "https://alphafold.ebi.ac.uk/entry/G3N3U8" } ], "lectin_list": [], "domain_list": [], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" }, { "name": "homologset.oma", "label": "OMA Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 121, "end_pos": 123 }, { "start_pos": 71, "end_pos": 73 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { 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"field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ], "tool_support": { "graph_view": "yes" } }, { "uniprot_canonical_ac": "F6RS73-1", "uniprot_ac": "F6RS73", "uniprot_id": "F6RS73_BOVIN", "mass": { "chemical_mass": 31177.0, "monoisotopic_mass": 31177.0 }, "refseq": { "ac": "XP_005212017", "name": "serine/arginine-rich splicing factor 5 isoform X2", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_005212017" }, "gene_names": [ { "name": "SRSF5", "type": "recommended", "evidence": [ { "id": "F6RS73", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F6RS73" } ] }, { "name": "SFRS5", "type": "synonym", "evidence": [ { "id": "XP_005212017", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_005212017" } ] }, { "name": "SRSF5", "type": "synonym", "evidence": [ { "id": "XP_005212017", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_005212017" } ] } ], "protein_names": [ { "name": "Serine/arginine-rich splicing factor 5", "type": "recommended", "evidence": [ { "id": "F6RS73", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F6RS73/entry#names_and_taxonomy" } ] }, { "name": "Delayed-early protein HRS", "type": "synonym", "evidence": [ { "id": "F6RS73", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F6RS73/entry#names_and_taxonomy" } ] }, { "name": "Pre-mRNA-splicing factor SRP40", "type": "synonym", "evidence": [ { "id": "F6RS73", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F6RS73/entry#names_and_taxonomy" } ] }, { "name": "Splicing factor, arginine/serine-rich 5", "type": "synonym", "evidence": [ { "id": "F6RS73", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F6RS73/entry#names_and_taxonomy" } ] }, { "name": "serine/arginine-rich splicing factor 5 isoform X2", "type": "synonym", "evidence": [ { "id": "XP_005212017", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_005212017" } ] } ], "function": [], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Bos taurus", "taxid": 9913, "evidence": [ { "database": "UniProtKB", "id": "F6RS73", "url": "https://www.uniprot.org/uniprotkb/F6RS73" } ], "common_name": "Bovine", "glygen_name": "Bovine", "reference_species": "Bos taurus [9913]" } ], "gene": [ { "name": "SRSF5", "url": "https://www.uniprot.org/uniprotkb/F6RS73", "locus": { "chromosome": "10", "start_pos": 81501228, "end_pos": 81495943, "strand": "-", "evidence": [ { "database": "Ensembl Gene", "id": "ENSBTAG00000011596", "url": "https://www.ensembl.org/id/ENSBTAG00000011596" } ] } } ], "crossref": [ { "id": "F6RS73", "url": "https://alphafold.ebi.ac.uk/entry/F6RS73", "database": "AlphaFoldDB", "categories": [] }, { "id": "cd12595", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd12595", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "cd12765", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd12765", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "510474", "url": "https://www.ncbi.nlm.nih.gov/gene/510474", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR000504", "url": "https://www.ebi.ac.uk/interpro/entry/IPR000504", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR012677", "url": "https://www.ebi.ac.uk/interpro/entry/IPR012677", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR035979", "url": "https://www.ebi.ac.uk/interpro/entry/IPR035979", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR050374", "url": "https://www.ebi.ac.uk/interpro/entry/IPR050374", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "PTHR23003", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR23003", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR23003:SF59", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR23003:SF59", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00076", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00076", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "XP_005212017", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_005212017", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A3Q1MNE3", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1MNE3", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A3Q1MNE3-1", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1MNE3-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0ABI0NUU0", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NUU0", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0ABI0NUU0-1", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NUU0-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "F6RS73", "url": "https://www.uniprot.org/uniprotkb/F6RS73", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "F6RS73-1", "url": "https://www.uniprot.org/uniprotkb/F6RS73-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MSGCRVFIGRLNPAAREKDVERFFKGYGRIRDIDLKRGFGFVEFEDPRDADDAVYELDGKELCSERVTIEHARARSRGGRGRGRYSDRFSSRRPRNDRRNAPPVRTENRLIVENLSSRVSWQDLKDFMRQAGEVTFADAHRPKLNEGVVEFASYGDLKNAIEKLSGKEINGRKIKLIEGSKRHRSRSRSRSRTRSSSRSRSRSRSRSRKSYSRSRSRSRSRSKSRSVSRSPVPEKSQKRGSSSRSKSPASVDRQRSRSRSRSRSRSVDSGN", "length": 271, "header": "tr|F6RS73-1|F6RS73_BOVIN Isoform 1 of Serine/arginine-rich splicing factor 5 OS=Bos taurus OX=9913 GN=SRSF5 PE=1 SV=1 CANONICAL=F6RS73-1" }, "isoforms": [ { "isoform_ac": "A0A3Q1MNE3-1", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1MNE3/entry", "sequence": { "sequence": "MSGCRVFIGRLNPAAREKDVERFFKGYGRIRDIDLKRGFGFVEFEDPRDADDAVYELDGKELCSERVTIEHARARSRGGRGRGRYSDRFSSRRPRNDRRNAPPVRTENRLIVENLSSRVSWQPICVVGLMTRSACGLS", "length": 138, "header": "tr|A0A3Q1MNE3-1|F6RS73_BOVIN Computationally mapped isoform of Serine/arginine-rich splicing factor 5 OS=Bos taurus OX=9913 GN=SRSF5 PE=1 SV=1 CANONICAL=F6RS73-1" }, "locus": { "chromosome": "10", "start_pos": 81498355, "end_pos": 81496952, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000081212.3", "url": "https://www.ensembl.org/id/ENSBTAT00000081212.3" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000073445.2", "url": "https://www.ensembl.org/id/ENSBTAP00000073445.2" } ] } }, { "isoform_ac": "A0ABI0NUU0-1", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NUU0/entry", "sequence": { "sequence": "MSGCRVFIGRLNPAAREKDVERFFKGYGRIRDIDLKRGFGFVEFEDPRDADDAVYELDGKELCSERVTIEHARARSRGGRGRGRYSDRFSSRRPRNDRRNAPPVRTENRLIVENLSSRVSWQVC", "length": 124, "header": "tr|A0ABI0NUU0-1|A0ABI0NUU0_BOVIN Computationally mapped isoform of Serine and arginine rich splicing factor 5 OS=Bos taurus OX=9913 GN=SRSF5 PE=1 SV=1 CANONICAL=F6RS73-1" }, "locus": { "chromosome": "10", "start_pos": 81498055, "end_pos": 81496952, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000145971.1", "url": "https://www.ensembl.org/id/ENSBTAT00000145971.1" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000104265.1", "url": "https://www.ensembl.org/id/ENSBTAP00000104265.1" } ] } }, { "isoform_ac": "F6RS73-1", "url": "https://www.uniprot.org/uniprotkb/F6RS73/entry", "sequence": { "sequence": "MSGCRVFIGRLNPAAREKDVERFFKGYGRIRDIDLKRGFGFVEFEDPRDADDAVYELDGKELCSERVTIEHARARSRGGRGRGRYSDRFSSRRPRNDRRNAPPVRTENRLIVENLSSRVSWQDLKDFMRQAGEVTFADAHRPKLNEGVVEFASYGDLKNAIEKLSGKEINGRKIKLIEGSKRHRSRSRSRSRTRSSSRSRSRSRSRSRKSYSRSRSRSRSRSKSRSVSRSPVPEKSQKRGSSSRSKSPASVDRQRSRSRSRSRSRSVDSGN", "length": 271, "header": "tr|F6RS73-1|F6RS73_BOVIN Isoform 1 of Serine/arginine-rich splicing factor 5 OS=Bos taurus OX=9913 GN=SRSF5 PE=1 SV=1 CANONICAL=F6RS73-1" }, "locus": { "chromosome": "10", "start_pos": 81500562, "end_pos": 81496952, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000015408.6", "url": "https://www.ensembl.org/id/ENSBTAT00000015408.6" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000015408.4", "url": "https://www.ensembl.org/id/ENSBTAP00000015408.4" } ] } } 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"name": "CMTM3", "url": "https://www.uniprot.org/uniprotkb/G3MWS4", "locus": { "chromosome": "18", "start_pos": 34357747, "end_pos": 34347291, "strand": "-", "evidence": [ { "database": "Ensembl Gene", "id": "ENSBTAG00000054188", "url": "https://www.ensembl.org/id/ENSBTAG00000054188" } ] } } ], "crossref": [ { "id": "G3MWS4", "url": "https://alphafold.ebi.ac.uk/entry/G3MWS4", "database": "AlphaFoldDB", "categories": [] }, { "id": "ENSBTAG00000054188", "url": "https://bgee.org/?page=gene&gene_id=ENSBTAG00000054188", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "IPR008253", "url": "https://www.ebi.ac.uk/interpro/entry/IPR008253", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR050578", "url": "https://www.ebi.ac.uk/interpro/entry/IPR050578", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "G3MWS4", "url": "https://www.orthodb.org/?gene=G3MWS4", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR22776", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR22776", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR22776:SF3", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR22776:SF3", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF01284", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF01284", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "A0A3Q1MQY9", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1MQY9", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A3Q1MQY9-1", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1MQY9-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0AAA9RWZ9", "url": "https://www.uniprot.org/uniprotkb/A0AAA9RWZ9", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0AAA9RWZ9-1", "url": "https://www.uniprot.org/uniprotkb/A0AAA9RWZ9-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "G3MWS4", "url": "https://www.uniprot.org/uniprotkb/G3MWS4", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "G3MWS4-1", "url": "https://www.uniprot.org/uniprotkb/G3MWS4-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "EGARPSLSIGRRRRHVAPRPGARPGPRARRPDPAQRGPSRAPCPPAGARLPLLAQRPPPAGGDDGKAEAPASRGFDPDQLQGLSFIIFVCYVASSASAFLTAPLLEFLLALCFLFADAMQLNDKWQGLCWPMMDFLRCVTAALIYFAISITAVAKYPDGASKAAGVFGFFATIVFAIDFYLIFNDVAKFLKQEDSAQETTADKAEEEDSDSDSD", "length": 214, "header": "tr|G3MWS4-1|G3MWS4_BOVIN Isoform 1 of CKLF like MARVEL transmembrane domain containing 3 OS=Bos taurus OX=9913 GN=CMTM3 PE=4 SV=3 CANONICAL=G3MWS4-1" }, "isoforms": [ { "isoform_ac": "A0A3Q1MQY9-1", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1MQY9/entry", "sequence": { "sequence": "MRAAESGFPLPSRAQGERERGRASASAAAAAMWPPDPEPDPDPEPAGRTQPSAALPGLRALLPARAFLCSLKGRLLLAETGLSFIIFVCYVASSASAFLTAPLLEFLLALCFLFADAMQLNDKWQGLCWPMMDFLRCVTAALIYFAISITAVAKYPDGASKAAGVFGFFATIVFAIDFYLIFNDVAKFLKQEDSAQETTADKAEEEDSDSDSD", "length": 213, "header": "tr|A0A3Q1MQY9-1|G3MWS4_BOVIN Computationally mapped isoform of CKLF like MARVEL transmembrane domain containing 3 OS=Bos taurus OX=9913 GN=CMTM3 PE=4 SV=1 CANONICAL=G3MWS4-1" }, "locus": { "chromosome": "18", "start_pos": 34355425, "end_pos": 34347500, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000068609.2", "url": "https://www.ensembl.org/id/ENSBTAT00000068609.2" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000072209.2", "url": "https://www.ensembl.org/id/ENSBTAP00000072209.2" } ] } }, { "isoform_ac": "A0AAA9RWZ9-1", "url": "https://www.uniprot.org/uniprotkb/A0AAA9RWZ9/entry", "sequence": { "sequence": "MWPPDPEPDPDPEPAGRTQPSAALPGLRALLPARAFLCSLKGRLLLAETGLSFIIFVCYVASSASAFLTAPLLEFLLALCFLFADAMQLNDKWQGLCWPMMVFGFFATIVFAIDFYLIFNDVAKFLKQEDSAQETTADKAEEEDSDSDSD", "length": 150, "header": "tr|A0AAA9RWZ9-1|G3MWS4_BOVIN Computationally mapped isoform of CKLF like MARVEL transmembrane domain containing 3 OS=Bos taurus OX=9913 GN=CMTM3 PE=4 SV=1 CANONICAL=G3MWS4-1" }, "locus": { "chromosome": "18", "start_pos": 34355425, "end_pos": 34347811, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000124322.2", "url": "https://www.ensembl.org/id/ENSBTAT00000124322.2" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000077008.1", "url": "https://www.ensembl.org/id/ENSBTAP00000077008.1" } ] } }, { "isoform_ac": "G3MWS4-1", "url": "https://www.uniprot.org/uniprotkb/G3MWS4/entry", "sequence": { "sequence": "EGARPSLSIGRRRRHVAPRPGARPGPRARRPDPAQRGPSRAPCPPAGARLPLLAQRPPPAGGDDGKAEAPASRGFDPDQLQGLSFIIFVCYVASSASAFLTAPLLEFLLALCFLFADAMQLNDKWQGLCWPMMDFLRCVTAALIYFAISITAVAKYPDGASKAAGVFGFFATIVFAIDFYLIFNDVAKFLKQEDSAQETTADKAEEEDSDSDSD", "length": 214, "header": "tr|G3MWS4-1|G3MWS4_BOVIN Isoform 1 of CKLF like MARVEL transmembrane domain containing 3 OS=Bos taurus OX=9913 GN=CMTM3 PE=4 SV=3 CANONICAL=G3MWS4-1" }, "locus": { "chromosome": "18", "start_pos": 34355425, "end_pos": 34347768, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000063380.3", "url": "https://www.ensembl.org/id/ENSBTAT00000063380.3" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000053978.3", "url": "https://www.ensembl.org/id/ENSBTAP00000053978.3" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [], "orthologs": [], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 3, "go_terms": [ { "name": "membrane", "id": "GO:0016020", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016020", "evidence": [ { "database": "UniProtKB", "id": "G3MWS4", "url": "https://www.uniprot.org/uniprotkb/G3MWS4" } ], "pmid": "" }, { "name": "cytosol", "id": "GO:0005829", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005829", "evidence": [ { "database": "UniProtKB", "id": "G3MWS4", "url": "https://www.uniprot.org/uniprotkb/G3MWS4" } ], "pmid": "" }, { "name": "cytoplasmic vesicle", "id": "GO:0031410", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0031410", "evidence": [ { "database": "UniProtKB", "id": "G3MWS4", "url": "https://www.uniprot.org/uniprotkb/G3MWS4" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [ { "pdb_id": "AF-G3MWS4-F1", "pdb_chain": "global", "start_pos": 1, "end_pos": 214, "overlap": "1.0", "method": "AlphaFold", "type": 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"tool_support": { "graph_view": "yes" } }, { "uniprot_canonical_ac": "G3N3U9-1", "uniprot_ac": "G3N3U9", "uniprot_id": "G3N3U9_BOVIN", "mass": { "chemical_mass": 40810.0, "monoisotopic_mass": 40810.0 }, "refseq": {}, "gene_names": [ { "name": "MRPS22", "type": "recommended", "evidence": [ { "id": "G3N3U9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3N3U9" } ] } ], "protein_names": [ { "name": "Mitochondrial ribosomal protein S22", "type": "synonym", "evidence": [ { "id": "G3N3U9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3N3U9/entry#names_and_taxonomy" } ] } ], "function": [], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Bos taurus", "taxid": 9913, "evidence": [ { "database": "UniProtKB", "id": "G3N3U9", "url": "https://www.uniprot.org/uniprotkb/G3N3U9" } ], "common_name": "Bovine", "glygen_name": "Bovine", "reference_species": "Bos taurus [9913]" } ], "gene": [ { "name": "MRPS22", "url": "https://www.uniprot.org/uniprotkb/G3N3U9", "locus": { "chromosome": "1", "start_pos": 129721997, "end_pos": 129754516, "strand": "+", "evidence": [ { "database": "Ensembl Gene", "id": "ENSBTAG00000047608", "url": "https://www.ensembl.org/id/ENSBTAG00000047608" } ] } } ], "crossref": [ { "id": "G3N3U9", "url": "https://alphafold.ebi.ac.uk/entry/G3N3U9", "database": "AlphaFoldDB", "categories": [] }, { "id": "ENSBTAG00000047608", "url": "https://bgee.org/?page=gene&gene_id=ENSBTAG00000047608", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "IPR019374", "url": "https://www.ebi.ac.uk/interpro/entry/IPR019374", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "GYIELTL", "url": "https://omabrowser.org/oma/group/GYIELTL/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "PTHR13071", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR13071", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR13071:SF4", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR13071:SF4", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF10245", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF10245", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "R-BTA-5389840", "url": "https://www.reactome.org/PathwayBrowser/#R-BTA-5389840", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "R-BTA-5419276", "url": "https://www.reactome.org/PathwayBrowser/#R-BTA-5419276", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "R-BTA-9937383", "url": "https://www.reactome.org/PathwayBrowser/#R-BTA-9937383", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "A0A3Q1MUW8", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1MUW8", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A3Q1MUW8-1", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1MUW8-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0AAA9S097", "url": "https://www.uniprot.org/uniprotkb/A0AAA9S097", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0AAA9S097-1", "url": "https://www.uniprot.org/uniprotkb/A0AAA9S097-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "G3N3U9", "url": "https://www.uniprot.org/uniprotkb/G3N3U9", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "G3N3U9-1", "url": "https://www.uniprot.org/uniprotkb/G3N3U9-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MMATLRVSLSLWNLHAGSRGAGRVYFRARARPRPGDLFQPLPGVCGAGTPCRGLCSEAESGSPKIKKPTFMDEEVQSILIKMTGLDLLKIFKPAVQETKPPTYKLMTQAQLEEATRQAIEAAKVRLKMPPVLEERTPINDVLAEDKILEGTETAKYVFTDISYSIPHRERFIVVREPSGTLRKASWEERDRMIQIYFPKEGRRVLTPVIFREENLQTMYSQDRHVDVLNLCVAQFEPDSADYIKVHHQTYEDIDKYGKYDLLRSTRHFGGMAWYFVNKKKIDGLLIDQIQRDLVDDAASLVQLYHILHPDGQSAQEAKEQAAEGLQLIKVFAKTEAQKGAYIELTLQAYQEAFISSSAAS", "length": 360, "header": "tr|G3N3U9-1|G3N3U9_BOVIN Isoform 1 of Mitochondrial ribosomal protein S22 OS=Bos taurus OX=9913 GN=MRPS22 PE=4 SV=2 CANONICAL=G3N3U9-1" }, "isoforms": [ { "isoform_ac": "A0A3Q1MUW8-1", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1MUW8/entry", "sequence": { "sequence": "MMATLRVSLSLWNLHAGSRGAGRVYFRARARPRPGDLFQPLPGVCGAGTPCRGLCSEAESGSPKIKKPTFMDEEVQSILIKMTGLDLLKIFKPAVQETKPPTYKLMTQAQLEEATRQAIEAAKVRLKMPPVLEERTPINDVLAEDKILEGTETAKYVFTDISYSIPHRERFIVVREPSGTLRKASWEERDRMIQIYFPKEGRRVLTPVIFREENLQTMYSQDRHVDVLNLCVAQFEPDSADYIKVHHQTYEDIDKYGKYDLLRSTRHFGGMAWYFVNKKKIDGLLIDQIQRDLVDDAASLVQLYHILHPDGQSAQEAKEQAAEGLQLIKSEVWGR", "length": 335, "header": "tr|A0A3Q1MUW8-1|G3N3U9_BOVIN Computationally mapped isoform of Mitochondrial ribosomal protein S22 OS=Bos taurus OX=9913 GN=MRPS22 PE=4 SV=2 CANONICAL=G3N3U9-1" }, "locus": { "chromosome": "1", "start_pos": 129754511, "end_pos": 129722089, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000081219.2", "url": "https://www.ensembl.org/id/ENSBTAT00000081219.2" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000074514.2", "url": "https://www.ensembl.org/id/ENSBTAP00000074514.2" } ] } }, { "isoform_ac": "A0AAA9S097-1", "url": "https://www.uniprot.org/uniprotkb/A0AAA9S097/entry", "sequence": { "sequence": "MMATLRVSLSLWNLHAGSRGAGRVYFRARARPRPGDLFQPLPGVCGAGTPCRGLCSEAESGSPKIKKPTFMDEEVQSILIKMTGLDLLKIFKPAVQETKPPTYKLMTQAQLEEATRQAIEAAKVRLKMPPVLEERTPINDVLAEDKILEGTETAKYVFTDISYSIPHRERFIVVREPSGTLRKASWEERDRMIQIYFPKEGRRVLTPVIFREENLQTMYSQDRHVDVLNLCVAQFEPDSADYIKVHHQTYEDIDKYGKYDLLRSTRHFGGMAWYFVNKKKIDGLLIDQIQRDLVDDAASLVQLYHILHPDGQSAQEAKEQAAEGLQLIKVGLLDF", "length": 335, "header": "tr|A0AAA9S097-1|G3N3U9_BOVIN Computationally mapped isoform of Mitochondrial ribosomal protein S22 OS=Bos taurus OX=9913 GN=MRPS22 PE=4 SV=1 CANONICAL=G3N3U9-1" }, "locus": { "chromosome": "1", "start_pos": 129754511, "end_pos": 129724373, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000114148.1", "url": "https://www.ensembl.org/id/ENSBTAT00000114148.1" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000079267.1", "url": "https://www.ensembl.org/id/ENSBTAP00000079267.1" } ] } }, { "isoform_ac": "G3N3U9-1", "url": "https://www.uniprot.org/uniprotkb/G3N3U9/entry", "sequence": { "sequence": "MMATLRVSLSLWNLHAGSRGAGRVYFRARARPRPGDLFQPLPGVCGAGTPCRGLCSEAESGSPKIKKPTFMDEEVQSILIKMTGLDLLKIFKPAVQETKPPTYKLMTQAQLEEATRQAIEAAKVRLKMPPVLEERTPINDVLAEDKILEGTETAKYVFTDISYSIPHRERFIVVREPSGTLRKASWEERDRMIQIYFPKEGRRVLTPVIFREENLQTMYSQDRHVDVLNLCVAQFEPDSADYIKVHHQTYEDIDKYGKYDLLRSTRHFGGMAWYFVNKKKIDGLLIDQIQRDLVDDAASLVQLYHILHPDGQSAQEAKEQAAEGLQLIKVFAKTEAQKGAYIELTLQAYQEAFISSSAAS", "length": 360, "header": "tr|G3N3U9-1|G3N3U9_BOVIN Isoform 1 of Mitochondrial ribosomal protein S22 OS=Bos taurus OX=9913 GN=MRPS22 PE=4 SV=2 CANONICAL=G3N3U9-1" }, "locus": { "chromosome": "1", "start_pos": 129754511, "end_pos": 129741142, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000063060.3", "url": "https://www.ensembl.org/id/ENSBTAT00000063060.3" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000056612.2", "url": "https://www.ensembl.org/id/ENSBTAP00000056612.2" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [ { "id": "R-BTA-5389840", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-BTA-5389840", "resource": "Reactome", "description": "Mitochondrial translation elongation" }, { "id": "R-BTA-5419276", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-BTA-5419276", "resource": "Reactome", "description": "Mitochondrial translation termination" }, { "id": "R-BTA-9937383", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-BTA-9937383", "resource": "Reactome", "description": "Mitochondrial ribosome-associated quality control" } ], "orthologs": [ { "uniprot_canonical_ac": "A0A5G2QNX8-1", "protein_name": "Mitochondrial ribosomal protein S22", "gene_name": "MRPS22", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MHELHKPSLGWGCKGEEDSATVWRTALPAQPSDAPGHLLEVLGTQRKIRADPAQRSPQPWRKESGNSEIRKPTFMDEEVQNILIKMTGLDLQKIFKPALQELKPPTYKLMTQAQLEEATKQAVEAAKVRLKMPPVLEERAPINDVLAEDKILEGTETAKYVFTDISYSIPHRERFIVVREPSGTLRKASWEERDRMIQVYFPREGRRILTPVIFKEENLQTMYSQDQHVDVLNLCVAQFEPDSAEYIKIHHHTYEDIDKCGKYDLLRSTRHFGGMAWYFVNKKKIDGLLIDQIQRDLVSDATSLVHLYHILHPDGQSAQEAKKQGAEGLHLIKVFAKTEAQKGAYIELTLQAYQEAFITHSAAS", "length": 364 }, "evidence": [ { "id": "G3N3U9", "url": "https://omabrowser.org/oma/group/G3N3U9/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "G3GSW2-1", "protein_name": "28S ribosomal protein S22, mitochondrial", "gene_name": "Mrps22", "tax_id": 10029, "organism": "Cricetulus griseus", "sequence": { "sequence": "MAALRTALLVWRFQLGSRRAQRVCPRAAAQRLPDALLATRPQPFEVGQPCRPLSSEADSHSSEVKKPTFMDEEVQSILTKMTGLDLKKTFKPAVQPLKPPTYKLMTQAQLEEATRLATEAAKVRLKMPPVLEERTPINDVLAEDKILEGTETHKYVFTDISYNIPHRERFIVVREPSGTLRKASWEERDRVIQIYFPKEGRRVLPPVIFKDENLKTMYSQDRHEDVLNLCVAQFEPDSTEYIKIHHQTYEDIDRHGKYDLLRSTRHFGGMAWYFVNKKKIDGLLIDQIQRDLIDDATSLVQLYHMLHPDGQSAQEAKEQDAKGVNLIKVFAKTEAQRGPYIELALQTYQEIVISHSAAS", "length": 359 }, "evidence": [ { "id": "G3N3U9", "url": "https://omabrowser.org/oma/group/G3N3U9/", "database": "OMA" } ], "glygen_name": "Hamster", "common_name": "Chinese hamster" }, { "uniprot_canonical_ac": "P82650-1", "protein_name": "Small ribosomal subunit protein mS22", "gene_name": "MRPS22", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MAPLGTTVLLWSLLRSSPGVERVCFRARIQPWHGGLLQPLPCSFEMGLPRRRFSSEAAESGSPETKKPTFMDEEVQSILTKMTGLNLQKTFKPAIQELKPPTYKLMTQAQLEEATRQAVEAAKVRLKMPPVLEERVPINDVLAEDKILEGTETTKYVFTDISYSIPHRERFIVVREPSGTLRKASWEERDRMIQVYFPKEGRKILTPIIFKEENLRTMYSQDRHVDVLNLCFAQFEPDSTEYIKVHHKTYEDIDKRGKYDLLRSTRYFGGMVWYFVNNKKIDGLLIDQIQRDLIDDATNLVQLYHVLHPDGQSAQGAKDQAAEGINLIKVFAKTEAQKGAYIELTLQTYQEALSRHSAAS", "length": 360 }, "evidence": [ { "id": "G3N3U9", "url": "https://omabrowser.org/oma/group/G3N3U9/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "Q9CXW2-1", "protein_name": "Small ribosomal subunit protein mS22", "gene_name": "Mrps22", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MAAVRTPLSLWRFQLGSRRARRVCTRATAQRHPDALLATRPQPFEVGQPRRLLSSEAESGSSEVKKPAFMDEEVQRILTKITGLDLQKTFRPAIQPLKPPTYKLMTQAQLEEATRLAVEAAKVRLKMPPVLEERKPINDVLAEDKILEGTETNKYVFTDISYNIPHRERFIVVREPSGTLRKASWEERDRVIQIYFPKEGRRVLPPVIFKDENLKTMYSQDRHADVLNLCVAQFEPDSAEYIKVHHQTYEDIDRHGKYELLRSTRHFGGMAWYFVNKKKIDGLLIDQIQRDLVDDATSLVQLYHMLHPDGQSAQEAKEQAAEGVDLIKVFAKTEAQRGAYIELALQTYQEIVTSHSAAS", "length": 359 }, "evidence": [ { "id": "G3N3U9", "url": "https://omabrowser.org/oma/group/G3N3U9/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" } ], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 1, "go_terms": [ { "name": "mitochondrial small ribosomal subunit", "id": "GO:0005763", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005763", "evidence": [ { "database": "UniProtKB", "id": "G3N3U9", "url": "https://www.uniprot.org/uniprotkb/G3N3U9" } ], "pmid": "" } ] }, { "name": "Molecular Function", "total": 1, "go_terms": [ { "name": "structural constituent of ribosome", "id": "GO:0003735", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003735", "evidence": [ { "database": "UniProtKB", "id": "G3N3U9", "url": "https://www.uniprot.org/uniprotkb/G3N3U9" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [ { "pdb_id": "AF-G3N3U9-F1", "pdb_chain": "global", "start_pos": 1, "end_pos": 360, "overlap": "1.0", "method": "AlphaFold", "type": "alphafold", "resolution": -1.0, "url": "https://data.glygen.org/ln2downloads/pdb/current/AF-G3N3U9-F1.pdb", "url_external": "https://alphafold.ebi.ac.uk/entry/G3N3U9" } ], "lectin_list": [], "domain_list": [], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" }, { "name": "homologset.oma", "label": "OMA Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ], "tool_support": { "graph_view": "yes" } }, { "uniprot_canonical_ac": "F6RLR4-1", "uniprot_ac": "F6RLR4", "uniprot_id": "F6RLR4_BOVIN", "mass": { "chemical_mass": 51893.0, "monoisotopic_mass": 51893.0 }, "refseq": { "ac": "NP_001157407", "name": "isthmin-1", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001157407" }, "gene_names": [ { "name": "ISM1", "type": "recommended", "evidence": [ { "id": "F6RLR4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F6RLR4" } ] }, { "name": "ISM1", "type": "synonym", "evidence": [ { "id": "NP_001157407", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001157407" } ] } ], "protein_names": [ { "name": "Isthmin 1", "type": "synonym", "evidence": [ { "id": "F6RLR4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F6RLR4/entry#names_and_taxonomy" } ] }, { "name": "isthmin 1 homolog", "type": "synonym", "evidence": [ { "id": "NP_001157407", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001157407" } ] }, { "name": "isthmin-1", "type": "synonym", "evidence": [ { "id": "NP_001157407", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001157407" } ] } ], "function": [], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Bos taurus", "taxid": 9913, "evidence": [ { "database": "UniProtKB", "id": "F6RLR4", "url": "https://www.uniprot.org/uniprotkb/F6RLR4" } ], "common_name": "Bovine", "glygen_name": "Bovine", "reference_species": "Bos taurus [9913]" } ], "gene": [ { "name": "ISM1", "url": "https://www.uniprot.org/uniprotkb/F6RLR4", "locus": { "chromosome": "13", "start_pos": 6912205, "end_pos": 6817037, "strand": "-", "evidence": [ { "database": "Ensembl Gene", "id": "ENSBTAG00000017188", "url": "https://www.ensembl.org/id/ENSBTAG00000017188" } ] } } ], "crossref": [ { "id": "F6RLR4", "url": "https://alphafold.ebi.ac.uk/entry/F6RLR4", "database": "AlphaFoldDB", "categories": [] }, { "id": "ENSBTAG00000017188", "url": "https://bgee.org/?page=gene&gene_id=ENSBTAG00000017188", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "506902", "url": "https://www.ncbi.nlm.nih.gov/gene/506902", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR000884", "url": "https://www.ebi.ac.uk/interpro/entry/IPR000884", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR005533", "url": "https://www.ebi.ac.uk/interpro/entry/IPR005533", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR036383", "url": "https://www.ebi.ac.uk/interpro/entry/IPR036383", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR051867", "url": "https://www.ebi.ac.uk/interpro/entry/IPR051867", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "bta:506902", "url": "https://www.genome.jp/dbget-bin/www_bget?bta:506902", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "FRQQNGH", "url": "https://omabrowser.org/oma/group/FRQQNGH/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "F6RLR4", "url": "https://www.orthodb.org/?gene=F6RLR4", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR10239", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR10239", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR10239:SF30", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR10239:SF30", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00090", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00090", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF03782", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF03782", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "NP_001157407", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001157407", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A3Q1MV95", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1MV95", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A3Q1MV95-1", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1MV95-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A3Q1NCN0", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1NCN0", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A3Q1NCN0-1", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1NCN0-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0AAA9SBZ6", "url": "https://www.uniprot.org/uniprotkb/A0AAA9SBZ6", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0AAA9SBZ6-1", "url": "https://www.uniprot.org/uniprotkb/A0AAA9SBZ6-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "F6RLR4", "url": "https://www.uniprot.org/uniprotkb/F6RLR4", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "F6RLR4-1", "url": "https://www.uniprot.org/uniprotkb/F6RLR4-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MVRLAAELLLLLGLLLLTLHITVLRGSGAADRPDAAAANASRTPLQNNLNMESASTSETSFPLSKEAPGEHSDHQAGHQPIPRQQFQQEVGHPSLQRDGPRSFLLDLPNFPDLSKADINGQNPNIQVTIEVVDGPDSEAEKDQHPENKPSWSVPSPDWRAWWQRSLALPRAQGGDQDYKYDGTSDDSNFLSPPGGWDRPAPGHRMFETKEQPEYDSTDGEGDWSLWSVCSVTCGNGNQKRTRSCGYACTATESRTCDRPSCPGIEDTFRTAATEVSLLAGSEEFNATKLFEVDTDSCERWMSCKSEFLKKYMHKVINDLPSCPCSYPTEVAYSTADIFDRIKRKDFRWKDASGPKEKLEIYKPTARYCIRSMLSLESTTLAAQHCCYGDNMQLITRGKGAGTPNLISTEFSAELHYKVDILPWIICKGDWSRYNEARPPNNGQKCTESPSDEDYIKQFQEAREY", "length": 464, "header": "tr|F6RLR4-1|F6RLR4_BOVIN Isoform 1 of Isthmin 1 OS=Bos taurus OX=9913 GN=ISM1 PE=3 SV=2 CANONICAL=F6RLR4-1" }, "isoforms": [ { "isoform_ac": "A0A3Q1MV95-1", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1MV95/entry", "sequence": { "sequence": "MMAFPGFLCFNNLNMESASTSETSFPLSKEAPGEHSDHQAGHQPIPRQQFQQEVGHPSLQRDGPRSFLLDLPNFPDLSKADINGQNPNIQVTIEVVDGPDSEAEKDQHPENKPSWSVPSPDWRAWWQRSLALPRAQGGDQDYKYDGTSDDSNFLSPPGGWDRPAPGHRMFETKEQPEYDSTDGEGDWSLWSVCSVTCGNGNQKRTRSCGYACTATESRTCDRPSCPGIEDTFRTAATEVSLLAGSEEFNATKLFEVDTDSCERWMSCKSEFLKKYMHKVINDLPSCPCSYPTEVAYSTADIFDRIKRKDFRWKDASGPKEKLEIYKPTARYCIRSMLSLESTTLAAQHCCYGDNMQLITRGKGAGTPNLISTEFSAELHYKVDILPWIICKGDWSRYNEARPPNNGQKCTESPSDEDYIKQFQEAREY", "length": 428, "header": "tr|A0A3Q1MV95-1|F6RLR4_BOVIN Computationally mapped isoform of Isthmin 1 OS=Bos taurus OX=9913 GN=ISM1 PE=3 SV=2 CANONICAL=F6RLR4-1" }, "locus": { "chromosome": "13", "start_pos": 6907915, "end_pos": 6870429, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000077734.2", "url": "https://www.ensembl.org/id/ENSBTAT00000077734.2" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000058885.2", "url": "https://www.ensembl.org/id/ENSBTAP00000058885.2" } ] } }, { "isoform_ac": "A0A3Q1NCN0-1", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1NCN0/entry", "sequence": { "sequence": "MVRLAAELLLLLGLLLLTLHITVLRGSGAADRPDAAAANASRTPLQNNLNMESASTSETSFPLSKEAPGEHSDHQAGHQPIPRQQFQQEVGHPSLQRDGPRSFLLDLPNFPDLSKADINGQNPNIQVTIEVVDGPDSEAEKDQHPENKPSWSVPSPDWRAWWQRSLALPRAQGGDQDYKYDGTSDDSNFLSPPGGWDRPAPGHRMFETKEQPEYDSTDGEGDWSLWSVCSVTCGNGNQKRTRSCGYACTATESRTCDRPSCPDTDSCERWMSCKSEFLKKYMHKVINDLPSCPCSYPTEVAYSTADIFDRIKRKDFRWKDASGPKEKLEIYKPTARYCIRSMLSLESTTLAAQHCCYGDNMQLITRGKGAGTPNLISTEFSAELHYKVDILPWIICKGDWSRYNEARPPNNGQKCTESPSDEDYIKQFQEAREY", "length": 434, "header": "tr|A0A3Q1NCN0-1|F6RLR4_BOVIN Computationally mapped isoform of Isthmin 1 OS=Bos taurus OX=9913 GN=ISM1 PE=3 SV=1 CANONICAL=F6RLR4-1" }, "locus": { "chromosome": "13", "start_pos": 6907915, "end_pos": 6817236, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000076964.2", "url": "https://www.ensembl.org/id/ENSBTAT00000076964.2" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000069169.1", "url": "https://www.ensembl.org/id/ENSBTAP00000069169.1" } ] } }, { "isoform_ac": "A0AAA9SBZ6-1", "url": "https://www.uniprot.org/uniprotkb/A0AAA9SBZ6/entry", "sequence": { "sequence": "MVRLAAELLLLLGLLLLTLHITVLRGSGAADRPDAAAANASRTPLQTGEGNSSAEKICLSPGRDAKIRSHSQRLKDLQEQEGIRNSSPLIGMQNNLNMESASTSETSFPLSKEAPGEHSDHQAGHQPIPRQQFQQEVGHPSLQRDGPRSFLLDLPNFPDLSKADINGQNPNIQVTIEVVDGPDSEAEKDQHPENKPSWSVPSPDWRAWWQRSLALPRAQGGDQDYKYDGTSDDSNFLSPPGGWDRPAPGHRMFETKEQPEYDSTDGEGDWSLWSVCSVTCGNGNQKRTRSCGYACTATESRTCDRPSCPGIEDTFRTAATEVSLLAGSEEFNATKLFEVDTDSCERWMSCKSEFLKKYMHKVINDLPSCPCSYPTEVAYSTADIFDRIKRKDFRWKDASGPKEKLEIYKPTARYCIRSMLSLESTTLAAQHCCYGDNMQLITRGKGAGTPNLISTEFSAELHYKVDILPWIICKGDWSRYNEARPPNNGQKCTESPSDEDYIKQFQEAREY", "length": 511, "header": "tr|A0AAA9SBZ6-1|F6RLR4_BOVIN Computationally mapped isoform of Isthmin 1 OS=Bos taurus OX=9913 GN=ISM1 PE=3 SV=1 CANONICAL=F6RLR4-1" }, "locus": { "chromosome": "13", "start_pos": 6907915, "end_pos": 6817236, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000100963.1", "url": "https://www.ensembl.org/id/ENSBTAT00000100963.1" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000083619.1", "url": "https://www.ensembl.org/id/ENSBTAP00000083619.1" } ] } }, { "isoform_ac": "F6RLR4-1", "url": "https://www.uniprot.org/uniprotkb/F6RLR4/entry", "sequence": { "sequence": "MVRLAAELLLLLGLLLLTLHITVLRGSGAADRPDAAAANASRTPLQNNLNMESASTSETSFPLSKEAPGEHSDHQAGHQPIPRQQFQQEVGHPSLQRDGPRSFLLDLPNFPDLSKADINGQNPNIQVTIEVVDGPDSEAEKDQHPENKPSWSVPSPDWRAWWQRSLALPRAQGGDQDYKYDGTSDDSNFLSPPGGWDRPAPGHRMFETKEQPEYDSTDGEGDWSLWSVCSVTCGNGNQKRTRSCGYACTATESRTCDRPSCPGIEDTFRTAATEVSLLAGSEEFNATKLFEVDTDSCERWMSCKSEFLKKYMHKVINDLPSCPCSYPTEVAYSTADIFDRIKRKDFRWKDASGPKEKLEIYKPTARYCIRSMLSLESTTLAAQHCCYGDNMQLITRGKGAGTPNLISTEFSAELHYKVDILPWIICKGDWSRYNEARPPNNGQKCTESPSDEDYIKQFQEAREY", "length": 464, "header": "tr|F6RLR4-1|F6RLR4_BOVIN Isoform 1 of Isthmin 1 OS=Bos taurus OX=9913 GN=ISM1 PE=3 SV=2 CANONICAL=F6RLR4-1" }, "locus": { "chromosome": "13", "start_pos": 6907915, "end_pos": 6817236, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000022843.6", "url": "https://www.ensembl.org/id/ENSBTAT00000022843.6" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000022843.6", "url": "https://www.ensembl.org/id/ENSBTAP00000022843.6" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [ { "id": "bta:506902", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?bta:506902", "resource": "KEGG Pathway" } ], "orthologs": [ { "uniprot_canonical_ac": "A0A8I5ZXL1-1", "protein_name": "Isthmin 1", "gene_name": "Ism1", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MVRLAAELLLLLGLLLLTLHITVLRGSGAADRQDAAASNVSGSQLQNNLNLESDSTSETSFPLSKEAPEEHQVVHQPFPRQRFPQETGHPSLQRDGPRSFLLDLPNFPDLSKADINGQNPNIQVTIEVVDGPDSEAEKDQHPENKPSWSLPAPDWRAWWQRSLSLARTNSGDQDDKYDSTSDDSNFLSVPRGWDRPAPGHRTFETKEQPEYDSTDGEGDWSLWSVCSVTCGNGNQKRTRSCGYACIATESRTCDRPNCPGIEDTFRTAATEVSLLAGSEEFNATKLFEVDMDSCERWMSCKSEFLKKYMHKVINDLPSCPCSYPTEVAYSTADIFDRIKRKDFRWKDASGPKEKLEIYKPTARYCIRSMLSLESTTLAAQHCCYGDNMQLITRGKGAGTPNLISTEFSAELHYKVDVLPWIICKGDWSRYNEARPPNNGQKCTESPSDEDYIKQFQEAREY", "length": 461 }, "evidence": [ { "id": "F6RLR4", "url": "https://omabrowser.org/oma/group/F6RLR4/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "A2ATD1-1", "protein_name": "Isthmin-1", "gene_name": "Ism1", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MVRLAAELLLLLGLLLLTLHITVLRGSGASDRQDAAAGNNNLNLESDSTSETSFPLSKEAPEEHQVVHQPFPRQRFPPETGHPSLQRDGPRSFLLDLPNFPDLSKADINGQNPNIQVTIEVVDGPDSEAEKDQHPENKPSWSLPAPDWRAWWQRSLSLARTNSGDQDDKYDSTSDDSNFLSVPRGWDRPAPGHRTFETKEQPEYDSTDGEGDWSLWSVCSVTCGNGNQKRTRSCGYACIATESRTCDRPNCPGIEDTFRTAATEVSLLAGSEEFNATKLFEVDMDSCERWMSCKSEFLKKYMHKVINDLPSCPCSYPTEVAYSTADIFDRIKRKDFRWKDASGPKEKLEIYKPTARYCIRSMLSLESTTLAAQHCCYGDNMQLITRGKGAGTPNLISTEFSAELHYKVDVLPWIICKGDWSRYNEARPPNNGQKCTESPSDEDYIKQFQEAREY", "length": 454 }, "evidence": [ { "id": "F6RLR4", "url": "https://omabrowser.org/oma/group/F6RLR4/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "B1AKI9-1", "protein_name": "Isthmin-1", "gene_name": "ISM1", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MVRLAAELLLLLGLLLLTLHITVLRGSGAADGPDAAAGNASQAQLQNNLNVGSDTTSETSFSLSKEAPREHLDHQAAHQPFPRPRFRQETGHPSLQRDFPRSFLLDLPNFPDLSKADINGQNPNIQVTIEVVDGPDSEADKDQHPENKPSWSVPSPDWRAWWQRSLSLARANSGDQDYKYDSTSDDSNFLNPPRGWDHTAPGHRTFETKDQPEYDSTDGEGDWSLWSVCSVTCGNGNQKRTRSCGYACTATESRTCDRPNCPGIEDTFRTAATEVSLLAGSEEFNATKLFEVDTDSCERWMSCKSEFLKKYMHKVMNDLPSCPCSYPTEVAYSTADIFDRIKRKDFRWKDASGPKEKLEIYKPTARYCIRSMLSLESTTLAAQHCCYGDNMQLITRGKGAGTPNLISTEFSAELHYKVDVLPWIICKGDWSRYNEARPPNNGQKCTESPSDEDYIKQFQEAREY", "length": 464 }, "evidence": [ { "id": "F6RLR4", "url": "https://omabrowser.org/oma/group/F6RLR4/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" } ], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 1, "go_terms": [ { "name": "extracellular region", "id": "GO:0005576", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005576", "evidence": [ { "database": "UniProtKB", "id": "F6RLR4", "url": "https://www.uniprot.org/uniprotkb/F6RLR4" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 1, "go_terms": [ { "name": "negative regulation of angiogenesis", "id": "GO:0016525", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016525", "evidence": [ { "database": "UniProtKB", "id": "F6RLR4", "url": "https://www.uniprot.org/uniprotkb/F6RLR4" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 285, "end_pos": 287, "annotation": "n_glycosylation_sequon" }, { "start_pos": 39, "end_pos": 41, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "F6RLR4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F6RLR4" }, { "id": "PS50856", "database": "PROSITE", "url": "https://prosite.expasy.org/PS50856" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "AMOP", "eco_id": "ECO_0000259", "start_pos": 289, "end_pos": 452, "start_aa": "Leu", "end_aa": "Glu", "glycosite_overlap": [] } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" }, { "name": "homologset.oma", "label": "OMA Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 285, "end_pos": 287 }, { "start_pos": 39, "end_pos": 41 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ], "tool_support": { "graph_view": "yes" } }, { "uniprot_canonical_ac": "G3N0L6-1", "uniprot_ac": "G3N0L6", "uniprot_id": "G3N0L6_BOVIN", "mass": { "chemical_mass": 31305.0, "monoisotopic_mass": 31305.0 }, "refseq": {}, "gene_names": [ { "name": "ACBD6", "type": "recommended", "evidence": [ { "id": "G3N0L6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3N0L6" } ] } ], "protein_names": [ { "name": "Acyl-CoA-binding domain-containing protein 6", "type": "recommended", "evidence": [ { "id": "G3N0L6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3N0L6/entry#names_and_taxonomy" } ] } ], "function": [], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Bos taurus", "taxid": 9913, "evidence": [ { "database": "UniProtKB", "id": "G3N0L6", "url": "https://www.uniprot.org/uniprotkb/G3N0L6" } ], "common_name": "Bovine", "glygen_name": "Bovine", "reference_species": "Bos taurus [9913]" } ], "gene": [ { "name": "ACBD6", "url": "https://www.uniprot.org/uniprotkb/G3N0L6", "locus": { "chromosome": "16", "start_pos": 61488363, "end_pos": 61683620, "strand": "+", "evidence": [ { "database": "Ensembl Gene", "id": "ENSBTAG00000046502", "url": "https://www.ensembl.org/id/ENSBTAG00000046502" } ] } } ], "crossref": [ { "id": "G3N0L6", "url": "https://alphafold.ebi.ac.uk/entry/G3N0L6", "database": "AlphaFoldDB", "categories": [] }, { "id": "ENSBTAG00000046502", "url": "https://bgee.org/?page=gene&gene_id=ENSBTAG00000046502", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "IPR000582", "url": "https://www.ebi.ac.uk/interpro/entry/IPR000582", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR002110", "url": "https://www.ebi.ac.uk/interpro/entry/IPR002110", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR014352", "url": "https://www.ebi.ac.uk/interpro/entry/IPR014352", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR035984", "url": "https://www.ebi.ac.uk/interpro/entry/IPR035984", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR036770", "url": "https://www.ebi.ac.uk/interpro/entry/IPR036770", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "ARSKWQA", "url": "https://omabrowser.org/oma/group/ARSKWQA/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "A0A3Q1MWI5", "url": "https://www.orthodb.org/?gene=A0A3Q1MWI5", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "G3N0L6", "url": "https://www.orthodb.org/?gene=G3N0L6", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR24119", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR24119", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR24119:SF0", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR24119:SF0", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00887", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00887", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF12796", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF12796", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "R-BTA-77289", "url": "https://www.reactome.org/PathwayBrowser/#R-BTA-77289", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "A0A3Q1MWI5", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1MWI5", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A3Q1MWI5-1", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1MWI5-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0AAA9TUV2", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TUV2", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0AAA9TUV2-1", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TUV2-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "G3N0L6", "url": "https://www.uniprot.org/uniprotkb/G3N0L6", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "G3N0L6-1", "url": "https://www.uniprot.org/uniprotkb/G3N0L6-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MASSFLPSGATTGDSGGELSSGDDSGDVESLQSPKIEASRSLPELFEKAAEHLQGLVQVASREQLLYLYARYKQVKVGNCNTPKPSFFDFEGKQKWEAWKALGDSSPSQAMQEYIAVVKKLDPSWNPQSPEKKGKEANTGFGGPVVSSLYHEEIIREEDKDIFDYCRENNIDHITKVIKTKNMDVNMKDEEGRTLLHWACDRGHKELVTVLLQYRADINCQDNEGQTALHYAAACEFLDIVELLLQSGADPMLRDQDGCLPEEVTGCKAVTLMLQQHTTGKA", "length": 282, "header": "tr|G3N0L6-1|G3N0L6_BOVIN Isoform 1 of Acyl-CoA-binding domain-containing protein 6 OS=Bos taurus OX=9913 GN=ACBD6 PE=4 SV=2 CANONICAL=G3N0L6-1" }, "isoforms": [ { "isoform_ac": "A0A3Q1MWI5-1", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1MWI5/entry", "sequence": { "sequence": "MASSFLPSGATTGDSGGELSSGDDSGDVESLQSPKIEASRSLPELFEKAAEHLQGLVQVASREQLLYLYARYKQVKVGNCNTPKPSFFDFEGKQKWEAWKALGDSSPSQAMQEYIAVVKKLDPSWNPQSPEKKGKEANTGFGGPVVSSLYHEEIIREEDKDIFDYCRENNIDHITKVIKTKNMDVNMKDEEVGNKYIVLCPVTIFLENCQNLGQSTAACEFLDIVELLLQSGADPMLRDQDGCLPEEVTGCKAVTLMLQQHTTGKA", "length": 266, "header": "tr|A0A3Q1MWI5-1|G3N0L6_BOVIN Computationally mapped isoform of Acyl-CoA-binding domain-containing protein 6 OS=Bos taurus OX=9913 GN=ACBD6 PE=4 SV=1 CANONICAL=G3N0L6-1" }, "locus": { "chromosome": "16", "start_pos": 61683337, "end_pos": 61489311, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000071932.2", "url": "https://www.ensembl.org/id/ENSBTAT00000071932.2" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000059837.1", "url": "https://www.ensembl.org/id/ENSBTAP00000059837.1" } ] } }, { "isoform_ac": "A0AAA9TUV2-1", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TUV2/entry", "sequence": { "sequence": "MASSFLPSGATTGDSGGELSSGDDSGDVESLQSPKIEASRSLPELFEKAAEHLQGLVQVASREQLLYLYARYKQVKVGNCNTPKPSFFDFEGKQKWEAWKALGDSSPSQAMQEYIAVVKKLDPSWNPQSPEKKGKEANTGFGGPVVSSLYHEEIIREEDKDIFDYCRENNIDHITKVIKTKNMDVNMKDEEGRTLLHWACDRGHKELVTVLLQYRADINCQEENFLYGNLMFNFLRKLQTVFYRSHTILHSHQRCN", "length": 256, "header": "tr|A0AAA9TUV2-1|G3N0L6_BOVIN Computationally mapped isoform of Acyl-CoA-binding domain-containing protein 6 OS=Bos taurus OX=9913 GN=ACBD6 PE=4 SV=1 CANONICAL=G3N0L6-1" }, "locus": { "chromosome": "16", "start_pos": 61683337, "end_pos": 61585010, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000112515.1", "url": "https://www.ensembl.org/id/ENSBTAT00000112515.1" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000100360.1", "url": "https://www.ensembl.org/id/ENSBTAP00000100360.1" } ] } }, { "isoform_ac": "G3N0L6-1", "url": "https://www.uniprot.org/uniprotkb/G3N0L6/entry", "sequence": { "sequence": "MASSFLPSGATTGDSGGELSSGDDSGDVESLQSPKIEASRSLPELFEKAAEHLQGLVQVASREQLLYLYARYKQVKVGNCNTPKPSFFDFEGKQKWEAWKALGDSSPSQAMQEYIAVVKKLDPSWNPQSPEKKGKEANTGFGGPVVSSLYHEEIIREEDKDIFDYCRENNIDHITKVIKTKNMDVNMKDEEGRTLLHWACDRGHKELVTVLLQYRADINCQDNEGQTALHYAAACEFLDIVELLLQSGADPMLRDQDGCLPEEVTGCKAVTLMLQQHTTGKA", "length": 282, "header": "tr|G3N0L6-1|G3N0L6_BOVIN Isoform 1 of Acyl-CoA-binding domain-containing protein 6 OS=Bos taurus OX=9913 GN=ACBD6 PE=4 SV=2 CANONICAL=G3N0L6-1" }, "locus": { "chromosome": "16", "start_pos": 61683337, "end_pos": 61489311, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000063346.3", "url": "https://www.ensembl.org/id/ENSBTAT00000063346.3" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000055381.2", "url": "https://www.ensembl.org/id/ENSBTAP00000055381.2" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [ { "id": "R-BTA-77289", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-BTA-77289", "resource": "Reactome", "description": "Mitochondrial Fatty Acid Beta-Oxidation" } ], "orthologs": [ { "uniprot_canonical_ac": "E1C483-1", "protein_name": "Acyl-CoA-binding domain-containing protein 6", "gene_name": "ACBD6", "tax_id": 9031, "organism": "Gallus gallus", "sequence": { "sequence": "MASPPLAAGSGGEGSSGSAGPDPSDRQLSALFEQAAERLPALLPNASKEQLLYLYARYKQVKFGTCNTPKPGFFDFEGKQKWEAWKALGDTSPHQAMQEYVATVKKLDPSWNPQTTEKRGKESKTAFGGPVVSSLYQEETIREEDKNIFDYCRENNIDYVTKAIQSKKVDVNVADEEGRALLHWACDRGHKELVSVLLQHAADVNSQDGEGQTALHYASACEFSDIVELLLQSGADPTLRDKEGCLPEEVTDCKAITSALQRHTAGKV", "length": 268 }, "evidence": [ { "id": "G3N0L6", "url": "https://omabrowser.org/oma/group/G3N0L6/", "database": "OMA" } ], "glygen_name": "Chicken", "common_name": "Chicken" }, { "uniprot_canonical_ac": "G3H7I4-1", "protein_name": "Acyl-CoA-binding domain-containing protein 6", "gene_name": "Acbd6", "tax_id": 10029, "organism": "Cricetulus griseus", "sequence": { "sequence": "MATPFLPAGATTGDSGGELSSGDDSGEMESSQNPETEASRNLDELFEKAAAHVQGLVHVASREQLLYLYARYKQVKVGNCNIPKPNFFDFEGKQKWEAWKALGDSSPRQAMQEYIAAVKKLDPGWKPQVSEKKGKEANNGFGGPVVSSLYHEETIREEDKNIFDYCRENNIDHVTKAIKSKSVEVNVKDEEGRAMLHWACDRGHKELVTVLLQYEADINCQDNEGQTALHYAAACEFLDIVELLLQSGADPTIRDQDDCLPEEVTGCKAVSLVLQLHRTNKA", "length": 282 }, "evidence": [ { "id": "G3N0L6", "url": "https://omabrowser.org/oma/group/G3N0L6/", "database": "OMA" } ], "glygen_name": "Hamster", "common_name": "Chinese hamster" }, { "uniprot_canonical_ac": "Q54GC8-1", "protein_name": "Acyl-CoA-binding domain-containing protein 6 homolog", "gene_name": "acbd6", "tax_id": 44689, "organism": "Dictyostelium discoideum", "sequence": { "sequence": "MTDAQIENKFKLAVDYITNNSGKLSNIKNEEQLYLYCNYKQATIGDCNTKAPPFYDYIGKSKWNSWNSLKGVEKIVAMNSYISLVNALSPGWDSNIKVERATQSVFLNDEEFKELEKKEKEEKEELKKLEEENGGEIEKPKSKWMGPVLSKFSLVDDETLEKLEKNTKQDLGYWVSVNDIERVKKEIENDKNIINEVDEDGRTALIWACDRGYFEIAKLLIENGSNVNVQDGEGMTPLHYAVVCDQFEICKLLLSQSSIDKSIKDNSDSIPSDFIDSSTSENIKSLFK", "length": 288 }, "evidence": [ { "id": "G3N0L6", "url": "https://omabrowser.org/oma/group/G3N0L6/", "database": "OMA" } ], "glygen_name": "Cellular slime mold", "common_name": "Social amoeba" }, { "uniprot_canonical_ac": "Q5RJK8-1", "protein_name": "Acyl-CoA-binding domain-containing protein 6", "gene_name": "Acbd6", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MATPFLPAGATTGDSGGELSSGDDSGDLESFQTPEAEATRSLAELFEKAAAHVQGLVQVASREQLLYLYARYKQVKVGNCNIPKPNFFDFEGKQKWEAWKALGDSSPSQAMQEYIAAVKKLDPGWNPQVSEKKGKEGSSGFGGPVVSSLYHEETIREEDKNIFDYCRENNIDHITKAIKSKTVDVNMTDEEGRALLHWACDRGHKELVKVLLQCEAGINCQDNEGQTALHYAAACEFSDIVELLLQSGADPTLRDQDGCLPEEVTGCKAVSLVLQLHRAGKA", "length": 282 }, "evidence": [ { "id": "G3N0L6", "url": "https://omabrowser.org/oma/group/G3N0L6/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "Q9BR61-1", "protein_name": "Acyl-CoA-binding domain-containing protein 6", "gene_name": "ACBD6", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MASSFLPAGAITGDSGGELSSGDDSGEVEFPHSPEIEETSCLAELFEKAAAHLQGLIQVASREQLLYLYARYKQVKVGNCNTPKPSFFDFEGKQKWEAWKALGDSSPSQAMQEYIAVVKKLDPGWNPQIPEKKGKEANTGFGGPVISSLYHEETIREEDKNIFDYCRENNIDHITKAIKSKNVDVNVKDEEGRALLHWACDRGHKELVTVLLQHRADINCQDNEGQTALHYASACEFLDIVELLLQSGADPTLRDQDGCLPEEVTGCKTVSLVLQRHTTGKA", "length": 282 }, "evidence": [ { "id": "G3N0L6", "url": "https://omabrowser.org/oma/group/G3N0L6/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "Q9D061-1", "protein_name": "Acyl-CoA-binding domain-containing protein 6", "gene_name": "Acbd6", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MATPFLPSGATTGDSGGELSSGDDSGDMESFQTPEAEGTRSLAELFEKAAAHVQGLVQVASREQLLYLYARFKQVKVGNCNTPKPNFFDFEGKQKWEAWKALGDSSPSQAMQEYIAAVKKLDPGWNPQVSEKKGKEGSSGFGGPVVSSLYHEETIREEDKNIFDYCRENNIDHIAKAIKSKAADVNMTDEEGRALLHWACDRGHKELVKVLLQYEAGINCQDNEGQTALHYAAACEFLDIVELLLQSGADPTLRDQDGCLPEEVTGCKAVSLLLQRHRASKA", "length": 282 }, "evidence": [ { "id": "G3N0L6", "url": "https://omabrowser.org/oma/group/G3N0L6/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q9SM23-1", "protein_name": "Acyl-CoA-binding domain-containing protein 1", "gene_name": "ACBP1", "tax_id": 3702, "organism": "Arabidopsis thaliana", "sequence": { "sequence": "MADWYQLAQSIIFGLIFAYLLAKLISILLAFKDENLSLTRNHTTQSEYENLRKVETLTGISGETDSLIAEQGSLRGDEDESDDDDWEGVESTELDEAFSAATAFVAAAASDRLSQKVSNELQLQLYGLYKIATEGPCTAPQPSALKMTARAKWQAWQKLGAMPPEEAMEKYIDLVTQLYPAWVEGGSKRRNRSGEAAGPMGPVFSSLVYEEESDNELKIDAIHAFAREGEVENLLKCIENGIPVNARDSEGRTPLHWAIDRGHLNVAEALVDKNADVNAKDNEGQTSLHYAVVCEREALAEFLVKQKADTTIKDEDGNSPLDLCESEWSWMREKKDSN", "length": 338 }, "evidence": [ { "id": "G3N0L6", "url": "https://omabrowser.org/oma/group/G3N0L6/", "database": "OMA" } ], "glygen_name": "Arabidopsis", "common_name": "Mouse-ear cress" }, { "uniprot_canonical_ac": "Q9VRG6-1", "protein_name": "Acyl-CoA-binding domain-containing protein 6", "gene_name": "Acbp-Ank", "tax_id": 7227, "organism": "Drosophila melanogaster", "sequence": { "sequence": "MSDSDTDTVDELFHLATEHVAKQSNSIGSADLLIFYGYYKQATNGPCKEQSPGLLQLQAKSKWQAWRNLGTMSQSAARQAYVQKLQELQPNWRSRRNPGWVVHSIESVPLEDQRLDSEKTLFDHVKENNLDRLRELLQPSDLVKLDEHGMALIHWATDRNAVEIIQFLVRSGASVNQRDAEQQTPLHYAASCGHLEALQCLLELHASLELRDSDGQTCYDVADDEQICQVLQTERERLAGSAS", "length": 243 }, "evidence": [ { "id": "G3N0L6", "url": "https://omabrowser.org/oma/group/G3N0L6/", "database": "OMA" } ], "glygen_name": "Fruit fly", "common_name": "Fruit fly" } ], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 3, "go_terms": [ { "name": "cytoplasm", "id": "GO:0005737", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005737", "evidence": [ { "database": "UniProtKB", "id": "G3N0L6", "url": "https://www.uniprot.org/uniprotkb/G3N0L6" } ], "pmid": "" }, { "name": "nucleus", "id": "GO:0005634", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005634", "evidence": [ { "database": "UniProtKB", "id": "G3N0L6", "url": "https://www.uniprot.org/uniprotkb/G3N0L6" } ], "pmid": "" }, { "name": "cytosol", "id": "GO:0005829", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005829", "evidence": [ { "database": "UniProtKB", "id": "G3N0L6", "url": "https://www.uniprot.org/uniprotkb/G3N0L6" } ], "pmid": "" } ] }, { "name": "Molecular Function", "total": 1, "go_terms": [ { "name": "fatty-acyl-CoA binding", "id": "GO:0000062", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000062", "evidence": [ { "database": "UniProtKB", "id": "G3N0L6", "url": "https://www.uniprot.org/uniprotkb/G3N0L6" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [ { "pdb_id": "AF-G3N0L6-F1", "pdb_chain": "global", "start_pos": 1, "end_pos": 282, "overlap": "1.0", "method": "AlphaFold", "type": "alphafold", "resolution": -1.0, "url": "https://data.glygen.org/ln2downloads/pdb/current/AF-G3N0L6-F1.pdb", "url_external": "https://alphafold.ebi.ac.uk/entry/G3N0L6" } ], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "G3N0L6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3N0L6" }, { "id": "PS51228", "database": "PROSITE", "url": "https://prosite.expasy.org/PS51228" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "ACB", "eco_id": "ECO_0000259", "start_pos": 42, "end_pos": 127, "start_aa": "Leu", "end_aa": "Pro", "glycosite_overlap": [] } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" }, { "name": "homologset.oma", "label": "OMA Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ], "tool_support": { "graph_view": "yes" } }, { "uniprot_canonical_ac": "G3MYY7-1", "uniprot_ac": "G3MYY7", "uniprot_id": "G3MYY7_BOVIN", "mass": { "chemical_mass": 31996.0, "monoisotopic_mass": 31996.0 }, "refseq": {}, "gene_names": [ { "name": "OPA3", "type": "recommended", "evidence": [ { "id": "G3MYY7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3MYY7" } ] } ], "protein_names": [ { "name": "Outer mitochondrial membrane lipid metabolism regulator OPA3", "type": "synonym", "evidence": [ { "id": "G3MYY7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3MYY7/entry#names_and_taxonomy" } ] } ], "function": [ { "annotation": "May play some role in mitochondrial processes.", "evidence": [ { "database": "UniProtKB", "id": "A0A3Q1NN25", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1NN25#function" }, { "database": "UniProtKB", "id": "ARBA00003027", "url": "https://www.uniprot.org/uniprotkb/ARBA00003027#function" }, { "database": "UniProtKB", "id": "A0AAA9RU72", "url": "https://www.uniprot.org/uniprotkb/A0AAA9RU72#function" }, { "database": "UniProtKB", "id": "G3MYY7", "url": "https://www.uniprot.org/uniprotkb/G3MYY7#function" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Bos taurus", "taxid": 9913, "evidence": [ { "database": "UniProtKB", "id": "G3MYY7", "url": "https://www.uniprot.org/uniprotkb/G3MYY7" } ], "common_name": "Bovine", "glygen_name": "Bovine", "reference_species": "Bos taurus [9913]" } ], "gene": [ { "name": "OPA3", "url": "https://www.uniprot.org/uniprotkb/G3MYY7", "locus": { "chromosome": "18", "start_pos": 53118230, "end_pos": 53185394, "strand": "+", "evidence": [ { "database": "Ensembl Gene", "id": "ENSBTAG00000019605", "url": "https://www.ensembl.org/id/ENSBTAG00000019605" } ] } } ], "crossref": [ { "id": "G3MYY7", "url": "https://alphafold.ebi.ac.uk/entry/G3MYY7", "database": "AlphaFoldDB", "categories": [] }, { "id": "ENSBTAG00000049026", "url": "https://bgee.org/?page=gene&gene_id=ENSBTAG00000049026", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "IPR010754", "url": "https://www.ebi.ac.uk/interpro/entry/IPR010754", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "PTHR12499", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR12499", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR12499:SF0", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR12499:SF0", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF07047", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF07047", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "A0A3Q1NN25", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1NN25", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A3Q1NN25-1", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1NN25-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0AAA9RU72", "url": "https://www.uniprot.org/uniprotkb/A0AAA9RU72", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0AAA9RU72-1", "url": "https://www.uniprot.org/uniprotkb/A0AAA9RU72-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "G3MYY7", "url": "https://www.uniprot.org/uniprotkb/G3MYY7", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "G3MYY7-1", "url": "https://www.uniprot.org/uniprotkb/G3MYY7-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MTSAEAGVGTHIGYSSRLTVPPSDSLTSAVYLHIHRSGRRSVSVYAVTSWTAPAVPPGRTHVRTHARRREGGGGGSDLRRPSQSARLRVPLATAKMVVGAFPMAKLLYLGIRQVSKPLANRIKEAARRSEFFKTYICLPPAQLYHWVEMRTKMRIMGFRGTVIKPLNEEAAAELGAELLGEATIFIVGGGCLVLEYWRHQAQQRRKEEEQRAAWDAMRDEVGHLALALEALQTQVQAAPPKGDLEELQAQMREVRAQLRAGDPPSTPGNQPPPPSFGLGHNPLEWLCRVF", "length": 290, "header": "tr|G3MYY7-1|G3MYY7_BOVIN Isoform 1 of Outer mitochondrial membrane lipid metabolism regulator OPA3 OS=Bos taurus OX=9913 GN=OPA3 PE=3 SV=1 CANONICAL=G3MYY7-1" }, "isoforms": [ { "isoform_ac": "A0A3Q1NN25-1", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1NN25/entry", "sequence": { "sequence": "MTSAEAGVGTHIGYSSRLTVPPSDSLTSAVYLHIHRSGRRSVSVYAVTSWTAPAVPPGRTHVRTHARRREGGGGGSDLRRPSQSARLRVPLATAKMVVGAFPMAKLLYLGIRQVSKPLANRIKEAARRSEFFKTYICLPPAQLYHWVEMRTKMRIMGFRGTVIKPLNEEAAAELGAELLGEATIFIVGGGCLVLEYWRHQAQQRRKEEEQRAAWDAMRDEVGHLALALEALQTQVQAAPPKGDLEELQAQMREVRAQLRAGDPPSTPGAASTSQAASSPKK", "length": 281, "header": "tr|A0A3Q1NN25-1|G3MYY7_BOVIN Computationally mapped isoform of Outer mitochondrial membrane lipid metabolism regulator OPA3 OS=Bos taurus OX=9913 GN=OPA3 PE=3 SV=2 CANONICAL=G3MYY7-1" }, "locus": { "chromosome": "18", "start_pos": 53185195, "end_pos": 53151998, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000067730.2", "url": "https://www.ensembl.org/id/ENSBTAT00000067730.2" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000074083.2", "url": "https://www.ensembl.org/id/ENSBTAP00000074083.2" } ] } }, { "isoform_ac": "A0AAA9RU72-1", "url": "https://www.uniprot.org/uniprotkb/A0AAA9RU72/entry", "sequence": { "sequence": "MTSAEAGVGTHIGYSSRLTVPPSDSLTSAVYLHIHRSGRRSVSVYAVTSWTAPAVPPGRTHVRTHARRREGGGGGSDLRRPSQSARLRVPLATAKMVVGAFPMAKLLYLGIRQVSKPLANRIKEAARRSEFFKTYICLPPAQLYHWVEMRAKMRLMGFNAETIKPLNEEAAAELGAELLGEATIFLVACGCLVLEYSRQKTQQRRKEGEQLAAWDAMRDEVDHLALVLEALQAQVQAAPPPGALEELQAQMREVRAQLCVQDLPPAPQEEPTPRDEGPPDPGLGQD", "length": 286, "header": "tr|A0AAA9RU72-1|G3MYY7_BOVIN Computationally mapped isoform of Outer mitochondrial membrane lipid metabolism regulator OPA3 OS=Bos taurus OX=9913 GN=OPA3 PE=3 SV=1 CANONICAL=G3MYY7-1" }, "locus": { "chromosome": "18", "start_pos": 53185195, "end_pos": 53119118, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000132205.1", "url": "https://www.ensembl.org/id/ENSBTAT00000132205.1" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000076693.1", "url": "https://www.ensembl.org/id/ENSBTAP00000076693.1" } ] } }, { "isoform_ac": "G3MYY7-1", "url": "https://www.uniprot.org/uniprotkb/G3MYY7/entry", "sequence": { "sequence": "MTSAEAGVGTHIGYSSRLTVPPSDSLTSAVYLHIHRSGRRSVSVYAVTSWTAPAVPPGRTHVRTHARRREGGGGGSDLRRPSQSARLRVPLATAKMVVGAFPMAKLLYLGIRQVSKPLANRIKEAARRSEFFKTYICLPPAQLYHWVEMRTKMRIMGFRGTVIKPLNEEAAAELGAELLGEATIFIVGGGCLVLEYWRHQAQQRRKEEEQRAAWDAMRDEVGHLALALEALQTQVQAAPPKGDLEELQAQMREVRAQLRAGDPPSTPGNQPPPPSFGLGHNPLEWLCRVF", "length": 290, "header": "tr|G3MYY7-1|G3MYY7_BOVIN Isoform 1 of Outer mitochondrial membrane lipid metabolism regulator OPA3 OS=Bos taurus OX=9913 GN=OPA3 PE=3 SV=1 CANONICAL=G3MYY7-1" }, "locus": { "chromosome": "18", "start_pos": 53185195, "end_pos": 53151309, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000064088.3", "url": "https://www.ensembl.org/id/ENSBTAT00000064088.3" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000054776.2", "url": "https://www.ensembl.org/id/ENSBTAP00000054776.2" } ] } } ], "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "other", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 266, "start_aa": "Thr", "end_pos": 266, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr266", "evidence": [ { "id": "", "database": "GlyGen", "url": "https://data.glygen.org/" } ], "filter_code": "000000000000000010000.00000000001000.0.01000" } ], "phosphorylation": [], "glycation": [], "keywords": [ "glycoprotein", "glycoprotein_predicted" ], "publication": [], "pathway": [], "orthologs": [], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 1, "go_terms": [ { "name": "mitochondrion", "id": "GO:0005739", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005739", "evidence": [ { "database": "UniProtKB", "id": "G3MYY7", "url": "https://www.uniprot.org/uniprotkb/G3MYY7" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 1, "go_terms": [ { "name": "regulation of lipid metabolic process", "id": "GO:0019216", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0019216", "evidence": [ { "database": "UniProtKB", "id": "G3MYY7", "url": "https://www.uniprot.org/uniprotkb/G3MYY7" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [ 266 ], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 1 }, { "field": "total_sites", "count": 1 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 1 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "exact_sites", "count": 1 }, { "field": "exact_o_linked_sites", "count": 1 }, { "field": "fuzzy_sites", "count": 0 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_pos", "start_aa", "end_pos", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 1 }, { "field": "total_sites", "count": 1 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 1 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "exact_sites", "count": 1 }, { "field": "exact_o_linked_sites", "count": 1 }, { "field": "fuzzy_sites", "count": 0 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_pos", "start_aa", "end_pos", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ], "tool_support": { "graph_view": "yes" } }, { "uniprot_canonical_ac": "G3N0Q8-1", "uniprot_ac": "G3N0Q8", "uniprot_id": "G3N0Q8_BOVIN", "mass": { "chemical_mass": 26504.0, "monoisotopic_mass": 26504.0 }, "refseq": { "ac": "XP_002689188", "name": "azurocidin", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_002689188" }, "gene_names": [ { "name": "AZU1", "type": "recommended", "evidence": [ { "id": "G3N0Q8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3N0Q8" } ] }, { "name": "AZU1", "type": "synonym", "evidence": [ { "id": "XP_002689188", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_002689188" } ] } ], "protein_names": [ { "name": "Azurocidin", "type": "recommended", "evidence": [ { "id": "G3N0Q8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3N0Q8/entry#names_and_taxonomy" } ] }, { "name": "Cationic antimicrobial protein CAP37", "type": "synonym", "evidence": [ { "id": "G3N0Q8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3N0Q8/entry#names_and_taxonomy" } ] }, { "name": "Heparin-binding protein", "type": "synonym", "evidence": [ { "id": "G3N0Q8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3N0Q8/entry#names_and_taxonomy" } ] }, { "name": "azurocidin", "type": "synonym", "evidence": [ { "id": "XP_002689188", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_002689188" } ] } ], "function": [], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Bos taurus", "taxid": 9913, "evidence": [ { "database": "UniProtKB", "id": "G3N0Q8", "url": "https://www.uniprot.org/uniprotkb/G3N0Q8" } ], "common_name": "Bovine", "glygen_name": "Bovine", "reference_species": "Bos taurus [9913]" } ], "gene": [ { "name": "AZU1", "url": "https://www.uniprot.org/uniprotkb/G3N0Q8", "locus": { "chromosome": "7", "start_pos": 43394879, "end_pos": 43387214, "strand": "-", "evidence": [ { "database": "Ensembl Gene", "id": "ENSBTAG00000045829", "url": "https://www.ensembl.org/id/ENSBTAG00000045829" } ] } } ], "crossref": [ { "id": "G3N0Q8", "url": "https://alphafold.ebi.ac.uk/entry/G3N0Q8", "database": "AlphaFoldDB", "categories": [] }, { "id": "ENSBTAG00000045829", "url": "https://bgee.org/?page=gene&gene_id=ENSBTAG00000045829", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "cd00190", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd00190", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "100336938", "url": "https://www.ncbi.nlm.nih.gov/gene/100336938", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR001254", "url": "https://www.ebi.ac.uk/interpro/entry/IPR001254", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR001314", "url": "https://www.ebi.ac.uk/interpro/entry/IPR001314", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR009003", "url": "https://www.ebi.ac.uk/interpro/entry/IPR009003", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR043504", "url": "https://www.ebi.ac.uk/interpro/entry/IPR043504", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "bta:100336938", "url": "https://www.genome.jp/dbget-bin/www_bget?bta:100336938", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "TAYRSWI", "url": "https://omabrowser.org/oma/group/TAYRSWI/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "G3N0Q8", "url": "https://www.orthodb.org/?gene=G3N0Q8", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR24271", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR24271", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR24271:SF10", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR24271:SF10", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00089", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00089", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "R-BTA-6798695", "url": "https://www.reactome.org/PathwayBrowser/#R-BTA-6798695", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "XP_002689188", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_002689188", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0AAA9RU90", "url": "https://www.uniprot.org/uniprotkb/A0AAA9RU90", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0AAA9RU90-1", "url": "https://www.uniprot.org/uniprotkb/A0AAA9RU90-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0AAA9SJV1", "url": "https://www.uniprot.org/uniprotkb/A0AAA9SJV1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0AAA9SJV1-1", "url": "https://www.uniprot.org/uniprotkb/A0AAA9SJV1-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "G3N0Q8", "url": "https://www.uniprot.org/uniprotkb/G3N0Q8", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "G3N0Q8-1", "url": "https://www.uniprot.org/uniprotkb/G3N0Q8-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "G3N2H4", "url": "https://www.uniprot.org/uniprotkb/G3N2H4", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "G3N2H4-1", "url": "https://www.uniprot.org/uniprotkb/G3N2H4-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MTALRLLAMLASLLATSRAGSAPLVDIVGGRKARPQELPFLASIQNQGRHFCGGALIHPNFVLTAASCFQSRNTGIATVVLGAYDLRRRERSRQTFFIRSVSENGYDPQQNLNDVLLLQLDRQANLTSSVALVPLPEQNATVEAGTGCQVAGWGTRRRRGRLSRVPRVLNVTVTPANQCRPNNVCTGVLTRRGGICQGDGGTPLVCNGLAHGVASWSRGPCGRGTDFFARVALFRNWIDSVINQPA", "length": 246, "header": "tr|G3N0Q8-1|G3N0Q8_BOVIN Isoform 1 of Azurocidin OS=Bos taurus OX=9913 GN=AZU1 PE=1 SV=2 CANONICAL=G3N0Q8-1" }, "isoforms": [ { "isoform_ac": "A0AAA9RU90-1", "url": "https://www.uniprot.org/uniprotkb/A0AAA9RU90/entry", "sequence": { "sequence": "MEEPREGSAERAGSAWSRASGLGSHPRVRAGASRTPRAGAGGGVGSALRPQAPHLARPRSEGGAGGGGGCGAAGTKPAPPPRGRRGGGERAAPPGLRPRAGRPGGCARGGGSLSRRVEGAARVRRRPRLPAPRPRSLGLSDLRPPQEGARTGLCGLFPSRAAQMVPGSPIQAGRGRDLRVSRVSAPLPGLMPTWTPFLCQAGAEPGLDSRWESLVLKGDHKLSSGGSAPLVDIVGGRKARPQELPFLASIQNQGRHFCGGALIHPNFVLTAASCFQSRNTGIATVVLGAYDLRRRERSRQTFFIRSVSENGYDPQQNLNDVLLLQLDRQANLTSSVALVPLPEQNATVEAGTGCQVAGWGTRRRRGRLSRVPRVLNVTVTPANQCRPNNVCTGVLTRRGGICQGDGGTPLVCNGLAHGVASWSRGPCGRGTDFFARVALFRNWIDSVINQPA", "length": 452, "header": "tr|A0AAA9RU90-1|G3N0Q8_BOVIN Computationally mapped isoform of Azurocidin OS=Bos taurus OX=9913 GN=AZU1 PE=1 SV=1 CANONICAL=G3N0Q8-1" }, "locus": { "chromosome": "7", "start_pos": 43394752, "end_pos": 43387413, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000114700.2", "url": "https://www.ensembl.org/id/ENSBTAT00000114700.2" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000075664.1", "url": "https://www.ensembl.org/id/ENSBTAP00000075664.1" } ] } }, { "isoform_ac": "A0AAA9SJV1-1", "url": "https://www.uniprot.org/uniprotkb/A0AAA9SJV1/entry", "sequence": { "sequence": "MVPGSPIQAGRGRDLRVSRVSAPLPGSAPLVDIVGGRKARPQELPFLASIQNQGRHFCGGALIHPNFVLTAASCFQSRNTGIATVVLGAYDLRRRERSRQTFFIRSVSENGYDPQQNLNDVLLLQLDRQANLTSSVALVPLPEQNATVEAGTGCQVAGWGTRRRRGRLSRVPRVLNVTVTPANQCRPNNVCTGVLTRRGGICQGDGGTPLVCNGLAHGVASWSRGPCGRGTDFFARVALFRNWIDSVINQPA", "length": 252, "header": "tr|A0AAA9SJV1-1|G3N0Q8_BOVIN Computationally mapped isoform of Azurocidin OS=Bos taurus OX=9913 GN=AZU1 PE=1 SV=1 CANONICAL=G3N0Q8-1" }, "locus": { "chromosome": "7", "start_pos": 43394752, "end_pos": 43387902, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000125223.2", "url": "https://www.ensembl.org/id/ENSBTAT00000125223.2" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000084106.1", "url": "https://www.ensembl.org/id/ENSBTAP00000084106.1" } ] } }, { "isoform_ac": "G3N0Q8-1", "url": "https://www.uniprot.org/uniprotkb/G3N0Q8/entry", "sequence": { "sequence": "MTALRLLAMLASLLATSRAGSAPLVDIVGGRKARPQELPFLASIQNQGRHFCGGALIHPNFVLTAASCFQSRNTGIATVVLGAYDLRRRERSRQTFFIRSVSENGYDPQQNLNDVLLLQLDRQANLTSSVALVPLPEQNATVEAGTGCQVAGWGTRRRRGRLSRVPRVLNVTVTPANQCRPNNVCTGVLTRRGGICQGDGGTPLVCNGLAHGVASWSRGPCGRGTDFFARVALFRNWIDSVINQPA", "length": 246, "header": "tr|G3N0Q8-1|G3N0Q8_BOVIN Isoform 1 of Azurocidin OS=Bos taurus OX=9913 GN=AZU1 PE=1 SV=2 CANONICAL=G3N0Q8-1" }, "locus": { "chromosome": "7", "start_pos": 43394752, "end_pos": 43391986, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000065019.4", "url": "https://www.ensembl.org/id/ENSBTAT00000065019.4" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000055424.2", "url": "https://www.ensembl.org/id/ENSBTAP00000055424.2" } ] } }, { "isoform_ac": "G3N2H4-1", "url": "https://www.uniprot.org/uniprotkb/G3N2H4/entry", "sequence": { "sequence": "GQAWGRGTGGCWPQFPRHKAQGGTVKQPSPGHTGSAPLVDIVGGRKARPQELPFLASIQNQGRHFCGGALIHPNFVLTAASCFQSRNTGIATVVLGAYDLRRRERSRQTFFIRSVSENGYDPQQNLNDVLLLQQLDRQANLTSSVALVPLPEQNATVEAGTGCQVAGWGTRRRRGRLSRVPRVLNVTVTPANQCRPNNVCTGVLTRRGGICQGDGGTPLVCNGLAHGVASWSRGPCGRGTDFFARVALFRNWIDSVINQPA", "length": 261, "header": "tr|G3N2H4-1|G3N2H4_BOVIN Computationally mapped isoform of Azurocidin OS=Bos taurus OX=9913 GN=AZU1 PE=1 SV=1 CANONICAL=G3N0Q8-1" }, "locus": { "chromosome": "7", "start_pos": 43394752, "end_pos": 43392099, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000063121.4", "url": "https://www.ensembl.org/id/ENSBTAT00000063121.4" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000056087.1", "url": "https://www.ensembl.org/id/ENSBTAP00000056087.1" } ] } } ], "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "other", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 174, "start_aa": "Thr", "end_pos": 174, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr174", "evidence": [ { "id": "", "database": "GlyGen", "url": "https://data.glygen.org/" } ], "filter_code": "000000000000000010000.00000000001000.0.01000" } ], "phosphorylation": [], "glycation": [], "keywords": [ "glycoprotein", "glycoprotein_predicted" ], "publication": [], "pathway": [ { "id": "bta:100336938", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?bta:100336938", "resource": "KEGG Pathway" }, { "id": "R-BTA-6798695", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-BTA-6798695", "resource": "Reactome", "description": "Neutrophil degranulation" } ], "orthologs": [ { "uniprot_canonical_ac": "P20160-1", "protein_name": "Azurocidin", "gene_name": "AZU1", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MTRLTVLALLAGLLASSRAGSSPLLDIVGGRKARPRQFPFLASIQNQGRHFCGGALIHARFVMTAASCFQSQNPGVSTVVLGAYDLRRRERQSRQTFSISSMSENGYDPQQNLNDLMLLQLDREANLTSSVTILPLPLQNATVEAGTRCQVAGWGSQRSGGRLSRFPRFVNVTVTPEDQCRPNNVCTGVLTRRGGICNGDGGTPLVCEGLAHGVASFSLGPCGRGPDFFTRVALFRDWIDGVLNNPGPGPA", "length": 251 }, "evidence": [ { "id": "G3N0Q8", "url": "https://omabrowser.org/oma/group/G3N0Q8/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "P80015-1", "protein_name": "Azurocidin", "gene_name": "AZU1", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MPALRFLALLASLLATSRVGLATLADIVGGRRAQPQEFPFLASIQKQGRPFCAGALVHPRFVLTAASCFRGKNSGSASVVLGAYDLRQQEQSRQTFSIRSISQNGYDPRQNLNDVLLLQLDREARLTPSVALVPLPPQNATVEAGTNCQVAGWGTQRLRRLFSRFPRVLNVTVTSNPCLPRDMCIGVFSRRGRISQGDRGTPLVCNGLAQGVASFLRRRFRRSSGFFTRVALFRNWIDSVLNNPPA", "length": 246 }, "evidence": [ { "id": "G3N0Q8", "url": "https://omabrowser.org/oma/group/G3N0Q8/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" } ], "go_annotation": { "categories": [ { "name": "Molecular Function", "total": 2, "go_terms": [ { "name": "serine-type endopeptidase activity", "id": "GO:0004252", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0004252", "evidence": [ { "database": "UniProtKB", "id": "G3N0Q8", "url": "https://www.uniprot.org/uniprotkb/G3N0Q8" } ], "pmid": "" }, { "name": "heparin binding", "id": "GO:0008201", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008201", "evidence": [ { "database": "UniProtKB", "id": "G3N0Q8", "url": "https://www.uniprot.org/uniprotkb/G3N0Q8" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 4, "go_terms": [ { "name": "proteolysis", "id": "GO:0006508", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006508", "evidence": [ { "database": "UniProtKB", "id": "G3N0Q8", "url": "https://www.uniprot.org/uniprotkb/G3N0Q8" } ], "pmid": "" }, { "name": "chemotaxis", "id": "GO:0006935", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006935", "evidence": [ { "database": "UniProtKB", "id": "G3N0Q8", "url": "https://www.uniprot.org/uniprotkb/G3N0Q8" } ], "pmid": "" }, { "name": "defense response to bacterium", "id": "GO:0042742", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0042742", "evidence": [ { "database": "UniProtKB", "id": "G3N0Q8", "url": "https://www.uniprot.org/uniprotkb/G3N0Q8" } ], "pmid": "" }, { "name": "protein maturation", "id": "GO:0051604", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0051604", "evidence": [ { "database": "UniProtKB", "id": "G3N0Q8", "url": "https://www.uniprot.org/uniprotkb/G3N0Q8" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 1, "go_terms": [ { "name": "extracellular space", "id": "GO:0005615", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005615", "evidence": [ { "database": "UniProtKB", "id": "G3N0Q8", "url": "https://www.uniprot.org/uniprotkb/G3N0Q8" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 125, "end_pos": 127, "annotation": "n_glycosylation_sequon" }, { "start_pos": 139, "end_pos": 141, "annotation": "n_glycosylation_sequon" }, { "start_pos": 170, "end_pos": 172, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [ { "pdb_id": "AF-G3N0Q8-F1", "pdb_chain": "global", "start_pos": 1, "end_pos": 246, "overlap": "1.0", "method": "AlphaFold", "type": "alphafold", "resolution": -1.0, "url": "https://data.glygen.org/ln2downloads/pdb/current/AF-G3N0Q8-F1.pdb", "url_external": "https://alphafold.ebi.ac.uk/entry/G3N0Q8" } ], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "G3N0Q8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3N0Q8" }, { "id": "PS50240", "database": "PROSITE", "url": "https://prosite.expasy.org/PS50240" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "Peptidase S1", "eco_id": "ECO_0000259", "start_pos": 27, "end_pos": 243, "start_aa": "Ile", "end_aa": "Asn", "glycosite_overlap": [] } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" }, { "name": "homologset.oma", "label": "OMA Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [ 174 ], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 125, "end_pos": 127 }, { "start_pos": 139, "end_pos": 141 }, { "start_pos": 170, "end_pos": 172 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 1 }, { "field": "total_sites", "count": 1 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 1 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "exact_sites", "count": 1 }, { "field": "exact_o_linked_sites", "count": 1 }, { "field": "fuzzy_sites", "count": 0 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_pos", "start_aa", "end_pos", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 1 }, { "field": "total_sites", "count": 1 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 1 }, { "field": 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"phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ], "tool_support": { "graph_view": "yes" } }, { "uniprot_canonical_ac": "F6RTS6-1", "uniprot_ac": "F6RTS6", "uniprot_id": "F6RTS6_BOVIN", "mass": { "chemical_mass": 56846.0, "monoisotopic_mass": 56846.0 }, "refseq": {}, "gene_names": [ { "name": "SLC22A31", "type": "recommended", "evidence": [ { "id": "F6RTS6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F6RTS6" } ] } ], "protein_names": [ { "name": "Solute carrier family 22 member 31", "type": "synonym", "evidence": [ { "id": "F6RTS6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F6RTS6/entry#names_and_taxonomy" } ] } ], "function": [], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Bos taurus", "taxid": 9913, "evidence": [ { "database": "UniProtKB", "id": "F6RTS6", "url": "https://www.uniprot.org/uniprotkb/F6RTS6" } ], "common_name": "Bovine", "glygen_name": "Bovine", "reference_species": "Bos taurus [9913]" } ], "gene": [ { "name": "SLC22A31", "url": "https://www.uniprot.org/uniprotkb/F6RTS6", "locus": { "chromosome": "18", "start_pos": 14277595, "end_pos": 14282345, "strand": "+", "evidence": [ { "database": "Ensembl Gene", "id": "ENSBTAG00000011533", "url": "https://www.ensembl.org/id/ENSBTAG00000011533" } ] } } ], "crossref": [ { "id": "F6RTS6", "url": "https://alphafold.ebi.ac.uk/entry/F6RTS6", "database": "AlphaFoldDB", "categories": [] }, { "id": "ENSBTAG00000011533", "url": "https://bgee.org/?page=gene&gene_id=ENSBTAG00000011533", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "IPR005828", "url": "https://www.ebi.ac.uk/interpro/entry/IPR005828", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR005829", "url": "https://www.ebi.ac.uk/interpro/entry/IPR005829", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR020846", "url": "https://www.ebi.ac.uk/interpro/entry/IPR020846", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR036259", "url": "https://www.ebi.ac.uk/interpro/entry/IPR036259", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "ASWVPCI", "url": "https://omabrowser.org/oma/group/ASWVPCI/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "F6RTS6", "url": "https://www.orthodb.org/?gene=F6RTS6", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR24064", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR24064", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00083", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00083", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "F6RTS6", "url": "https://www.uniprot.org/uniprotkb/F6RTS6", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "F6RTS6-1", "url": "https://www.uniprot.org/uniprotkb/F6RTS6-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MEHEARVLRLAGGFGRARCLLAAASWLPCVALGLALGSELLLTALPAHHCGSDPARAPSTCLPLSYPESVPRAGSDGARPCSRGWYYAQPAADLLRSPVTQRNLVCEDGWKVPLEQVDHLLGRLLGCVLLGLGCDWFGRRAVFVGSLVLATGLGVGEALVASFPALLTLRLLRGGALAGASLALYVARLELCDPPNRLAFSMGAGLFSVVGTLLLPGLALLAQDWQLLQGLSALATGLLLLFWGFPAMFPESPCWLLATGQPARARRILWHFAKASGVDPENSTEEESSLAMELDVLCAGHPQPRHHSVLELRHTHVTWRNALILGFSSLISGGIRASFLHSLVPSEPSFYWPYFLAAGLEAAATVFLLLTADLWGRRSVLLLSTLVLVLASQLLLAGAQYLPSWMVLFLSVLGLLASQTVSALSSLFSAEIFPTVIRGAGLGLVLGAGFLGQAAVPLTTMHGRHGFFLQHVLFASFALLALLCVLLLPESRGRTLPQSLQEADRLCRSPLLRGCPRQDLLPLLPASSWGRN", "length": 532, "header": "tr|F6RTS6-1|F6RTS6_BOVIN Isoform 1 of Solute carrier family 22 member 31 OS=Bos taurus OX=9913 GN=SLC22A31 PE=4 SV=2 CANONICAL=F6RTS6-1" }, "isoforms": [ { "isoform_ac": "F6RTS6-1", "url": "https://www.uniprot.org/uniprotkb/F6RTS6/entry", "sequence": { "sequence": "MEHEARVLRLAGGFGRARCLLAAASWLPCVALGLALGSELLLTALPAHHCGSDPARAPSTCLPLSYPESVPRAGSDGARPCSRGWYYAQPAADLLRSPVTQRNLVCEDGWKVPLEQVDHLLGRLLGCVLLGLGCDWFGRRAVFVGSLVLATGLGVGEALVASFPALLTLRLLRGGALAGASLALYVARLELCDPPNRLAFSMGAGLFSVVGTLLLPGLALLAQDWQLLQGLSALATGLLLLFWGFPAMFPESPCWLLATGQPARARRILWHFAKASGVDPENSTEEESSLAMELDVLCAGHPQPRHHSVLELRHTHVTWRNALILGFSSLISGGIRASFLHSLVPSEPSFYWPYFLAAGLEAAATVFLLLTADLWGRRSVLLLSTLVLVLASQLLLAGAQYLPSWMVLFLSVLGLLASQTVSALSSLFSAEIFPTVIRGAGLGLVLGAGFLGQAAVPLTTMHGRHGFFLQHVLFASFALLALLCVLLLPESRGRTLPQSLQEADRLCRSPLLRGCPRQDLLPLLPASSWGRN", "length": 532, "header": "tr|F6RTS6-1|F6RTS6_BOVIN Isoform 1 of Solute carrier family 22 member 31 OS=Bos taurus OX=9913 GN=SLC22A31 PE=4 SV=2 CANONICAL=F6RTS6-1" }, "locus": { "chromosome": "18", "start_pos": 14282146, "end_pos": 14277749, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000015324.7", "url": "https://www.ensembl.org/id/ENSBTAT00000015324.7" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000015324.6", "url": "https://www.ensembl.org/id/ENSBTAP00000015324.6" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [], "orthologs": [], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 2, "go_terms": [ { "name": "membrane", "id": "GO:0016020", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016020", "evidence": [ { "database": "UniProtKB", "id": "F6RTS6", "url": "https://www.uniprot.org/uniprotkb/F6RTS6" } ], "pmid": "" }, { "name": "endomembrane system", "id": "GO:0012505", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0012505", "evidence": [ { "database": "UniProtKB", "id": "F6RTS6", "url": "https://www.uniprot.org/uniprotkb/F6RTS6" } ], "pmid": "" } ] }, { "name": "Molecular Function", "total": 1, "go_terms": [ { "name": "transmembrane transporter activity", "id": "GO:0022857", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0022857", "evidence": [ { "database": "UniProtKB", "id": "F6RTS6", "url": "https://www.uniprot.org/uniprotkb/F6RTS6" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 282, "end_pos": 284, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "F6RTS6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F6RTS6" }, { "id": "PS50850", "database": "PROSITE", "url": "https://prosite.expasy.org/PS50850" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "Major facilitator superfamily (MFS) profile", "eco_id": "ECO_0000259", "start_pos": 30, "end_pos": 493, "start_aa": "Val", "end_aa": "Gly", "glycosite_overlap": [] } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], 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{ "name": "LOC132342124", "url": "https://www.uniprot.org/uniprotkb/G5E5U2", "locus": {} } ], "crossref": [ { "id": "G5E5U2", "url": "https://alphafold.ebi.ac.uk/entry/G5E5U2", "database": "AlphaFoldDB", "categories": [] }, { "id": "ENSBTAG00000047954", "url": "https://bgee.org/?page=gene&gene_id=ENSBTAG00000047954", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "cd07765", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd07765", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "cd07936", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd07936", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "100125581", "url": "https://www.ncbi.nlm.nih.gov/gene/100125581", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR001909", "url": "https://www.ebi.ac.uk/interpro/entry/IPR001909", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR003309", "url": "https://www.ebi.ac.uk/interpro/entry/IPR003309", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR013087", "url": "https://www.ebi.ac.uk/interpro/entry/IPR013087", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR036051", "url": "https://www.ebi.ac.uk/interpro/entry/IPR036051", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR036236", "url": "https://www.ebi.ac.uk/interpro/entry/IPR036236", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR038269", "url": "https://www.ebi.ac.uk/interpro/entry/IPR038269", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "G3N002", "url": "https://www.orthodb.org/?gene=G3N002", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "G5E5U2", "url": "https://www.orthodb.org/?gene=G5E5U2", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR23226", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR23226", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR23226:SF272", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR23226:SF272", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00096", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00096", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF01352", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF01352", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF02023", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF02023", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "R-BTA-212436", "url": "https://www.reactome.org/PathwayBrowser/#R-BTA-212436", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "A0AAA9RV67", "url": "https://www.uniprot.org/uniprotkb/A0AAA9RV67", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0AAA9RV67-1", "url": "https://www.uniprot.org/uniprotkb/A0AAA9RV67-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0AAA9SBP0", "url": "https://www.uniprot.org/uniprotkb/A0AAA9SBP0", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0AAA9SBP0-1", "url": "https://www.uniprot.org/uniprotkb/A0AAA9SBP0-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0AAA9THB6", "url": "https://www.uniprot.org/uniprotkb/A0AAA9THB6", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0AAA9THB6-1", "url": "https://www.uniprot.org/uniprotkb/A0AAA9THB6-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0AAA9TP40", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TP40", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0AAA9TP40-1", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TP40-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0AAA9TYN4", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TYN4", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0AAA9TYN4-1", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TYN4-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "G3N002", "url": "https://www.uniprot.org/uniprotkb/G3N002", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "G3N002-1", "url": "https://www.uniprot.org/uniprotkb/G3N002-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "G5E5U2", "url": "https://www.uniprot.org/uniprotkb/G5E5U2", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "G5E5U2-1", "url": "https://www.uniprot.org/uniprotkb/G5E5U2-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MSQIEEKLFPEQIMMSPVKAPACLYPHVEVLQGTKRSVKESSNKSKKSSPQMGSLHPESARQHFRSFCYHDTPGPYEAVSHLQELCSQWLRPEIHSKEQILELLVLEQFLDVLPSHIQNWVQKYHPQNVKEAVALVDRFHRECGGISNEVTTHQLGNDTVLLGGTAVAPGFKWKPAEPQPMGVFQGESSNIYQVLQEPRWNTHKESQPVDEGAVPAEESPTFSEEKSTPSCKLASKLTLPKSQSPLTFEDVALYFSEEEWRIMTPEQKTLYFDVMGELYEDVTFLGLKLKNDTGNDPPVSLPTLEIQPSGCEVLRKATMKDAETTMGDVNHGGTCRVWKRPRAFPGRKRKKLKTCKQELPKPVDVHGKGCEGEKPFKCQECGKSFRVSSDLIKHQRVHTEERPYKCEQCDKQFRWSSDLNKHLMAHQGIKPYRCSWCGKSFSHNTNLHTHLRIHTGEKPFKCYECGKRFIQNSHLIKHQRTHTGEQPYTCSICNRNFSRRSSLLRHQKLHKRRESCPVSPV", "length": 521, "header": "tr|G5E5U2-1|G5E5U2_BOVIN Isoform 1 of Zinc finger protein 75D OS=Bos taurus OX=9913 GN=LOC132342124 PE=3 SV=3 CANONICAL=G5E5U2-1" }, "isoforms": [ { "isoform_ac": "A0AAA9RV67-1", "url": "https://www.uniprot.org/uniprotkb/A0AAA9RV67/entry", "sequence": { "sequence": "MPLGRRSTHWFCTKADKASVIRWPRRMSQVGEKLFPEQIMMSPVKAPACLYPHVEVLQGTKRSVKESSNKSKKSSPQMGSLHPESARQHFRRFCYHDTPGPYEAVSQLQELCSQWLRPEIHSKEQILELLVLEQFLDVLPSHIQNWVQKYQPQNVKEAVALVDRFQRESGGISNEVTAHELGNDTALLGGTAVAPGFKWKPAEPQPMGVFQEECSNIYQVLQELGWNTHKESQPVDEGAVPAEESQTFSKQKITPSWNMASELTWPQSLSPLTFEDVALYFSEEEWKIMTPDEKTLYLDVMQDVYEDVASVGLKLKNDTGNDPPVSLPTLEIQPSGCEVLRKATMKDAETTMGDVNHGGTCRVWKRPRAFPGRKRKKLKTCKQELPKPVDVHGKGCEGEKPFKCQECGKSFRVSSDLIKHQRVHTEERPYKCEQCDKQFRWSSDLNKHLMAHQGIKPYRCSWCGKSFSHNTNLHTHLRIHTGEKPFKCYECGKRFIQNSHLIKHQRTHTGEQPYTCSICNRNFSRRSSLLRHQKLHKRRESCPVSPV", "length": 547, "header": "tr|A0AAA9RV67-1|G5E5U2_BOVIN Computationally mapped isoform of Zinc finger protein 75D OS=Bos taurus OX=9913 GN=LOC132342124 PE=3 SV=1 CANONICAL=G5E5U2-1" }, "locus": { "chromosome": "X", "start_pos": 18948667, "end_pos": 18926984, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000094437.2", "url": "https://www.ensembl.org/id/ENSBTAT00000094437.2" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000077180.1", "url": "https://www.ensembl.org/id/ENSBTAP00000077180.1" } ] } }, { "isoform_ac": "A0AAA9SBP0-1", "url": "https://www.uniprot.org/uniprotkb/A0AAA9SBP0/entry", "sequence": { "sequence": "MSQIEEKLFPEQIMMSPVKAPACLYPHVEVLQGTKRMSQIEEKLFPEQIMMSPVKAPACLYPHVEVLQGTKRSVKESSNKSKKSSPQMGSLHPESARQHFRRFCYHDTPGPYEAVSQLQELCSQWLRPEIHSKEQILELLVLEQFLDVLPSHIQNWVQKYQPQNVKEAVALVDRFQRESGGISNEVTAHELGNDTALLGGTAVAPGFKWKPAEPQPMGVFQEECSNIYQVLQELGWNTHKESQPVDEGAVPAEESQTFSKQKITPSWNMASELTWPQSLSPLTFEDVALYFSEEEWKIMTPDEKTLYLDVMQDVYEDVASVGLKLKNDTGNDPPVSLPTLEIQPSGCEVLRKATMKDAETTMGDVNHGGTCRVWKRPRAFPGRKRKKLKTCKQELPKPVDVHGKGCEGEKPFKCQECGKSFRVSSDLIKHQRVHTEERPYKCEQCDKQFRWSSDLNKHLMAHQGIKPYRCSWCGKSFSHNTNLHTHLRIHTGEKPFKCYECGKRFIQNSHLIKHQRTHTGEQPYTCSICNRNFSRRSSLLRHQKLHKRRESCPVSPV", "length": 557, "header": "tr|A0AAA9SBP0-1|G5E5U2_BOVIN Computationally mapped isoform of Zinc finger protein 75D OS=Bos taurus OX=9913 GN=LOC132342124 PE=3 SV=1 CANONICAL=G5E5U2-1" }, "locus": { "chromosome": "X", "start_pos": 18948667, "end_pos": 18917170, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000114616.2", "url": "https://www.ensembl.org/id/ENSBTAT00000114616.2" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000083503.1", "url": "https://www.ensembl.org/id/ENSBTAP00000083503.1" } ] } }, { "isoform_ac": "A0AAA9THB6-1", "url": "https://www.uniprot.org/uniprotkb/A0AAA9THB6/entry", "sequence": { "sequence": "MSQIEEKLFPEQIMMSPVKAPACLYPHVEVLQGTKRSVKESSNKSKKSSPQMGSLHPESARQHFRSFCYHDTPGPYEAVSHLQELCSQWLRPEIHSKEQILELLVLEQFLDVLPSHIQNWVQKYHPQNVKEAVALVDRFHRECGGISNEVTAHELGNDTALLGGTAVAPGFKWKPAEPQPMGVFQEECSNIYQVLQELGWNTHKESQPVDEGAVPAEESQTFSKQKITPSWNMASELTWPQSLSPLTFEDVALYFSEEEWKIMTPDEKTLYLDVMQDVYEDVASVGLKLKNDTGNDPPVSLPTLEIQPSGCEVLRKATMKDAETTMGDVNHGGTCRVWKRPRAFPGRKRKKLKTCKQELPKPVDVHGKGCEGEKPFKCQECGKSFRVSSDLIKHQRVHTEERPYKCEQCDKQFRWSSDLNKHLMAHQGIKPYRCSWCGKSFSHNTNLHTHLRIHTGEKPFKCYECGKRFIQNSHLIKHQRTHTGEQPYTCSICNRNFSRRSSLLRHQKLHKRRESCPVSPV", "length": 521, "header": "tr|A0AAA9THB6-1|G5E5U2_BOVIN Computationally mapped isoform of Zinc finger protein 75D OS=Bos taurus OX=9913 GN=LOC132342124 PE=3 SV=1 CANONICAL=G5E5U2-1" }, "locus": { "chromosome": "X", "start_pos": 18948667, "end_pos": 18917170, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000106830.2", "url": "https://www.ensembl.org/id/ENSBTAT00000106830.2" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000096264.1", "url": "https://www.ensembl.org/id/ENSBTAP00000096264.1" } ] } }, { "isoform_ac": "A0AAA9TP40-1", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TP40/entry", "sequence": { "sequence": "MSQVGEKLFPEQIMMSPVKAPACLYPHVEVLQGTKRSVKESSNKSKKSSPQMGSLHPESARQHFRRFCYHDTPGPYEAVSQLQELCSQWLRPEIHSKEQILELLVLEQFLDVLPSHIQNWVQKYQPQNVKEAVALVDRFQRESGGISNEVTAHELGNDTALLGGTAVAPGFKWKPAEPQPMGVFQEECSNIYQVLQELGWNTHKESQPVDEGAVPAEESQTFSKQKITPSWNMASELTWPQSLSPLTFEDVALYFSEEEWKIMTPDEKTLYLDVMQDVYEDVASVGLKLKNDTGNDPPVSLPTLEIQPSGCEVLRKATMKDAETTMGDVNHGGTCRVWKRPRAFPGRKRKKLKTCKQELPKPVDVHGKGCEGEKPFKCQECGKSFRVSSDLIKHQRVHTEERPYKCEQCDKQFRWSSDLNKHLMAHQGIKPYRCSWCGKSFSHNTNLHTHLRIHTGEKPFKCYECGKRFIQNSHLIKHQRTHTGEQPYTCSICNRNFSRRSSLLRHQKLHKRRESCPVSPV", "length": 521, "header": "tr|A0AAA9TP40-1|G5E5U2_BOVIN Computationally mapped isoform of Zinc finger protein 75D OS=Bos taurus OX=9913 GN=LOC132342124 PE=3 SV=1 CANONICAL=G5E5U2-1" }, "locus": { "chromosome": "X", "start_pos": 18948667, "end_pos": 18939350, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000132104.2", "url": "https://www.ensembl.org/id/ENSBTAT00000132104.2" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000098789.1", "url": "https://www.ensembl.org/id/ENSBTAP00000098789.1" } ] } }, { "isoform_ac": "A0AAA9TYN4-1", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TYN4/entry", "sequence": { "sequence": "MSQIEEKLFPEQIMMSPVKAPACLYPHVEVLQGTKRSVKESSNKSKKSSPQMGSLHPESARQHFRSFCYHDTPGPYEAVSHLQELCSQWLRPEIHSKEQILELLVLEQFLDVLPSHIQNWVQKYHPQNVKEAVALVDRFHRECGGISNEVTTHQLGNDTVLLGGTAVAPGFKWKPAEPQPMGVFQGESSNIYQVLQEPRWNTHKESQPVDEGAVPAEESQTFSKQKITPSWNMASELTWPQSLSPLTFEDVALYFSEEEWKIMTPDEKTLYLDVMQDVYEDVASVGLKLKNDTGNDPPVSLPTLEIQPSGCEVLRKATMKDAETTMGDVNHGGTCRVWKRPRAFPGRKRKKLKTCKQELPKPVDVHGKGCEGEKPFKCQECGKSFRVSSDLIKHQRVHTEERPYKCEQCDKQFRWSSDLNKHLMAHQGIKPYRCSWCGKSFSHNTNLHTHLRIHTGEKPFKCYECGKRFIQNSHLIKHQRTHTGEQPYTCSICNRNFSRRSSLLRHQKLHKRRESCPVSPV", "length": 521, "header": "tr|A0AAA9TYN4-1|A0AAA9TYN4_BOVIN Computationally mapped isoform of Zinc finger protein 75D OS=Bos taurus OX=9913 GN=LOC132342124 PE=3 SV=2 CANONICAL=G5E5U2-1" }, "locus": { "chromosome": "X", "start_pos": 18948667, "end_pos": 18917170, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000127373.2", "url": "https://www.ensembl.org/id/ENSBTAT00000127373.2" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000103460.2", "url": "https://www.ensembl.org/id/ENSBTAP00000103460.2" } ] } }, { "isoform_ac": "G3N002-1", "url": "https://www.uniprot.org/uniprotkb/G3N002/entry", "sequence": { "sequence": "MSQIEEKLFPEQIMMSPVKAPACLYPHVEVLQGTKRSVKESSNKSKKSSPQMGSLHPESARQHFRSFCYHDTPGPYEAVSHLQELCSQWLRPEIHSKEQILELLVLEQFLDVLPSHIQNWVQKYHPQNVKEAVALVDRFHRECGGISNEVTTHQLGNDTVLLGGTAVAPGFKWKPAEPQPMGVFQGESSNIYQVLQEPRWNTHKESQPVDEGAVPAEESPTFSEEKSTPSCKLASKLTLPKSQSPLTFEDVALYFSEEEWKIMTPDEKTLYLDVMQDVYEDVASVGLKLKNDTGNDPPVSLPTLEIQPSGCEVLRKATMKDAETTMGDVNHGGTCRVWKRPRAFPGRKRKKLKTCKQELPKPVDVHGKGCEGEKPFKCQECGKSFRVSSDLIKHQRVHTEERPYKCEQCDKQFRWSSDLNKHLMAHQGIKPYRCSWCGKSFSHNTNLHTHLRIHTGEKPFKCYECGKRFIQNSHLIKHQRTHTGEQPYTCSICNRNFSRRSSLLRHQKLHKRRESCPVSPV", "length": 521, "header": "tr|G3N002-1|G3N002_BOVIN Computationally mapped isoform of Zinc finger protein 75D OS=Bos taurus OX=9913 GN=LOC132342124 PE=3 SV=4 CANONICAL=G5E5U2-1" }, "locus": { "chromosome": "X", "start_pos": 18948667, "end_pos": 18917170, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000065493.4", "url": "https://www.ensembl.org/id/ENSBTAT00000065493.4" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000055156.4", "url": "https://www.ensembl.org/id/ENSBTAP00000055156.4" } ] } }, { "isoform_ac": "G5E5U2-1", "url": "https://www.uniprot.org/uniprotkb/G5E5U2/entry", "sequence": { "sequence": "MSQIEEKLFPEQIMMSPVKAPACLYPHVEVLQGTKRSVKESSNKSKKSSPQMGSLHPESARQHFRSFCYHDTPGPYEAVSHLQELCSQWLRPEIHSKEQILELLVLEQFLDVLPSHIQNWVQKYHPQNVKEAVALVDRFHRECGGISNEVTTHQLGNDTVLLGGTAVAPGFKWKPAEPQPMGVFQGESSNIYQVLQEPRWNTHKESQPVDEGAVPAEESPTFSEEKSTPSCKLASKLTLPKSQSPLTFEDVALYFSEEEWRIMTPEQKTLYFDVMGELYEDVTFLGLKLKNDTGNDPPVSLPTLEIQPSGCEVLRKATMKDAETTMGDVNHGGTCRVWKRPRAFPGRKRKKLKTCKQELPKPVDVHGKGCEGEKPFKCQECGKSFRVSSDLIKHQRVHTEERPYKCEQCDKQFRWSSDLNKHLMAHQGIKPYRCSWCGKSFSHNTNLHTHLRIHTGEKPFKCYECGKRFIQNSHLIKHQRTHTGEQPYTCSICNRNFSRRSSLLRHQKLHKRRESCPVSPV", "length": 521, "header": "tr|G5E5U2-1|G5E5U2_BOVIN Isoform 1 of Zinc finger protein 75D OS=Bos taurus OX=9913 GN=LOC132342124 PE=3 SV=3 CANONICAL=G5E5U2-1" }, "locus": { "chromosome": "X", "start_pos": 18948667, "end_pos": 18917170, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000031011.6", "url": "https://www.ensembl.org/id/ENSBTAT00000031011.6" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000030975.6", "url": "https://www.ensembl.org/id/ENSBTAP00000030975.6" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [ { "id": "R-BTA-212436", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-BTA-212436", "resource": "Reactome", "description": "Generic Transcription Pathway" } ], "orthologs": [], "go_annotation": { "categories": [ { "name": "Molecular Function", "total": 4, "go_terms": [ { "name": "DNA binding", "id": "GO:0003677", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003677", "evidence": [ { "database": "UniProtKB", "id": "G5E5U2", "url": "https://www.uniprot.org/uniprotkb/G5E5U2" } ], "pmid": "" }, { "name": "zinc ion binding", "id": "GO:0008270", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008270", "evidence": [ { "database": "UniProtKB", "id": "G5E5U2", "url": "https://www.uniprot.org/uniprotkb/G5E5U2" } ], "pmid": "" }, { "name": "RNA polymerase II cis-regulatory region sequence-specific DNA binding", "id": "GO:0000978", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000978", "evidence": [ { "database": "UniProtKB", "id": "G5E5U2", "url": "https://www.uniprot.org/uniprotkb/G5E5U2" } ], "pmid": "" }, { "name": "DNA-binding transcription factor activity, RNA polymerase II-specific", "id": "GO:0000981", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000981", "evidence": [ { "database": "UniProtKB", "id": "G5E5U2", "url": "https://www.uniprot.org/uniprotkb/G5E5U2" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 1, "go_terms": [ { "name": "nucleus", "id": "GO:0005634", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005634", "evidence": [ { "database": "UniProtKB", "id": "G5E5U2", "url": "https://www.uniprot.org/uniprotkb/G5E5U2" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 3, "go_terms": [ { "name": "DNA-templated transcription", "id": "GO:0006351", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006351", "evidence": [ { "database": "UniProtKB", "id": "G5E5U2", "url": "https://www.uniprot.org/uniprotkb/G5E5U2" } ], "pmid": "" }, { "name": "regulation of DNA-templated transcription", "id": "GO:0006355", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006355", "evidence": [ { "database": "UniProtKB", "id": "G5E5U2", "url": "https://www.uniprot.org/uniprotkb/G5E5U2" } ], "pmid": "" }, { "name": "regulation of transcription by RNA polymerase II", "id": "GO:0006357", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006357", "evidence": [ { "database": "UniProtKB", "id": "G5E5U2", "url": "https://www.uniprot.org/uniprotkb/G5E5U2" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 157, "end_pos": 159, "annotation": "n_glycosylation_sequon" }, { "start_pos": 291, "end_pos": 293, "annotation": "n_glycosylation_sequon" }, { "start_pos": 43, "end_pos": 45, "annotation": "n_glycosylation_sequon" }, { "start_pos": 496, "end_pos": 498, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": 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"categories": [ "Protein" ] }, { "id": "G3MZK6", "url": "https://www.uniprot.org/uniprotkb/G3MZK6", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "G3MZK6-1", "url": "https://www.uniprot.org/uniprotkb/G3MZK6-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MHENRAFSNCKGLGPFLREWKWGGEIAAANAIAEERRSQGSFSSLPSQPSNIKSPFKPVIDGSVLKNDIKQRLAKERREEKKRQDDANKETQLLEKERKSKIVYEKQMEEKQRKLREQKEKDEQRRISAEKKRNEMLEEEREKFKAVLHRTLERSSRVDRQKRWSWAGYTTVNSQNKTVNKHSTSTEKLEQGTCGLHRQMSSTGLQNSVAKKTPEKRRSSSLNRRCSIHSVIQYVNIPLLRHSSDELKSTIVPRQSTAVMPFQEKVEIPSKTSVGVAPKASVEVPPEVSVEALTKASLDESPQVNVEAPPEVSVEAFPEETMKKHPKVSVETFLEASMKEHPGVNVEALAEESMKEHPKVRVDALLEVSMKEHPAVSVEALPEESMKEHPAVSVEALAEESMKEHPKVRVDALLKVSMKEHPEVSVEALVEASMKEHPAVNVEALAEASMKEHPKKSEMDEQPSNPITKKRIPPSQIPCYRWSSSPTRRWRPPSPISASRQIQKNCPPSPSPGTSKQSTQFCFSYKVIPTQRTVFAQNALGTMGMKSKAVSNTINNSEAPSQKDMICEESGNKGTPGPKNAEEATKILAEKRRLAREQKEKEERLQKEMEQRKMKDVAKKVDDGQEDEFSKFGDGQQPKEMKKRESQEQEDQKVELQKSDAKIKAQEEADKRKKEHERIMLQNLQERLERKKVWRSVTLRRPESLELSLPSGKKGTLSLPACTPSNKTHDSIASLRCILFINISFTHGLFRQKSCSQSSDWFAIICA", "length": 767, "header": "tr|G3MZK6-1|G3MZK6_BOVIN Isoform 1 of MAP7 domain containing 3 OS=Bos taurus OX=9913 GN=MAP7D3 PE=3 SV=4 CANONICAL=G3MZK6-1" }, "isoforms": [ { "isoform_ac": "A0AAA9RZT2-1", "url": "https://www.uniprot.org/uniprotkb/A0AAA9RZT2/entry", "sequence": { "sequence": "IRSQGSFSSLPSQPSNIKSPFKPVIDGSVLKNDIKQRLAKERREEKKRQDDANKETQLLEKERKSKIVYEKQMEEKQRKLREQKEKDEQRRISAEKKRNEMLEEEREKFKAVLHRTLERSSRVDRQKRWSWAGYTTVNSQNKTVNKHSTSTEKLEQGTCGLHRQMSSTGLQNSVAKKTPEKRRSSSLNRRCSIHSVIQYVNIPLLRHSSDELKSTIVPRQSTAVMPFQEKVEIPSKTSVGVAPKASVEVPPEVSVEALTKASLDESPQVNVEAPPEVSVEAFPEETMKKHPKVSVETFLEASMKEHPGVNVEALAEESMKEHPKVRVDALLEVSMKEHPAVSVEALPEESMKEHPAVSVEALVSMKEHPEVSVEALVEASMKEHPAVNVEALAEASMKEHPKVSVDSLPEVKMDEQPSNPITKKRIPPSQIPCYRWSSSPTRRWRPPSPISASRQIQKNCPPSPSPGTSKQSTQFCFSYKVIPTQRTVFAQNALGTMGMKSKAVSNTINNSEAPSQKDMICEESGNKGTPGPKNAEEATKILAEKRRLAREQKEKEERLQKEMEQRKMKDVAKKVDDGQEDEFSKFGDGQQPKEMKKRESQEQEDQKVELQKSDAKIKAQEEADKRKKEHERIMLQNLQERLERKKVWRSVTLRRPESLELSLPSGKKGTLSLPACTPSNKTHDSIASLRCILFINISFTHGLFRQKSCSQSSDWFAIICA", "length": 721, "header": "tr|A0AAA9RZT2-1|G3MZK6_BOVIN Computationally mapped isoform of MAP7 domain containing 3 OS=Bos taurus OX=9913 GN=MAP7D3 PE=3 SV=2 CANONICAL=G3MZK6-1" }, "locus": { "chromosome": "NKLS02002208.1", "start_pos": 8679614, "end_pos": 8655710, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000102231.2", "url": "https://www.ensembl.org/id/ENSBTAT00000102231.2" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000079110.2", "url": "https://www.ensembl.org/id/ENSBTAP00000079110.2" } ] } }, { "isoform_ac": "F1N469-1", "url": "https://www.uniprot.org/uniprotkb/F1N469/entry", "sequence": { "sequence": "MIFIFSLSKGNGGVPWWSRGQDSAVTAEGSIRGWGTLPQALRFAAANAIAEERRSQGSFSSLPSQPSNIKSPFKPVIDGSVLKNDIKQRLAKERREEKKRQDDANKETQLLEKERKSKIVYEKQMEEKQRKLREQKEKDEQRRISAEKKRNEMLEEEREKFKAVLHRTLERSSRVDRQKRWSWAGYTTVNSQNKTVNKHSTSTEKLEQGTCGLHRQMSSTGLQNSVAKKTPEKRRSSSLNRRCSIHSVIQYVNIPLLRHSSDELKSTIVPRQSTAVMPFQEKVEIPSKTSVGVAPKASVEVPPEVSVEALTKASLDESPQVNVEAPPEVSVEAFPEETMKKHPKVSVETFLEASMKEHPGVNVEALAEESMKEHPKVRVDALLEVSMKEHPAVSVEALPEESMKEHPAVSVEALAEESMKEHPKVRVDALLKVSMKEHPEVSVEALVEASMKEHPAVNVEALAEASMKEHPKKSEMDEQPSNPITKKRIPPSQIPCYRWSSSPTRRWRPPSPISASRQIQKNCPPSPSPGTSKQSTQFCFSYKVIPTQRTVFAQNALGTMGMKSKAVSNTINNSEAPSQKDMICEESGNKGTPGPKNAEEATKILAEKRRLAREQKEKEERLQKEMEQRKMKDVAKKVDDGQEDEFSKFGDGQQPKEMKKRESQEQEDQKVELQKSDAKIKAQEEADKRKKEHERIMLQNLQERLERKKVCLFSNTSKFLDVTSSHIHKETKAFLNTDMKTFRQKGVKDPLNQTKKYTWEGL", "length": 762, "header": "tr|F1N469-1|G3MZK6_BOVIN Computationally mapped isoform of MAP7 domain containing 3 OS=Bos taurus OX=9913 GN=MAP7D3 PE=3 SV=5 CANONICAL=G3MZK6-1" }, "locus": { "chromosome": "NKLS02002208.1", "start_pos": 8682837, "end_pos": 8653621, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000048938.5", "url": "https://www.ensembl.org/id/ENSBTAT00000048938.5" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000045892.5", "url": "https://www.ensembl.org/id/ENSBTAP00000045892.5" } ] } }, { "isoform_ac": "G3MZK6-1", "url": "https://www.uniprot.org/uniprotkb/G3MZK6/entry", "sequence": { "sequence": "MHENRAFSNCKGLGPFLREWKWGGEIAAANAIAEERRSQGSFSSLPSQPSNIKSPFKPVIDGSVLKNDIKQRLAKERREEKKRQDDANKETQLLEKERKSKIVYEKQMEEKQRKLREQKEKDEQRRISAEKKRNEMLEEEREKFKAVLHRTLERSSRVDRQKRWSWAGYTTVNSQNKTVNKHSTSTEKLEQGTCGLHRQMSSTGLQNSVAKKTPEKRRSSSLNRRCSIHSVIQYVNIPLLRHSSDELKSTIVPRQSTAVMPFQEKVEIPSKTSVGVAPKASVEVPPEVSVEALTKASLDESPQVNVEAPPEVSVEAFPEETMKKHPKVSVETFLEASMKEHPGVNVEALAEESMKEHPKVRVDALLEVSMKEHPAVSVEALPEESMKEHPAVSVEALAEESMKEHPKVRVDALLKVSMKEHPEVSVEALVEASMKEHPAVNVEALAEASMKEHPKKSEMDEQPSNPITKKRIPPSQIPCYRWSSSPTRRWRPPSPISASRQIQKNCPPSPSPGTSKQSTQFCFSYKVIPTQRTVFAQNALGTMGMKSKAVSNTINNSEAPSQKDMICEESGNKGTPGPKNAEEATKILAEKRRLAREQKEKEERLQKEMEQRKMKDVAKKVDDGQEDEFSKFGDGQQPKEMKKRESQEQEDQKVELQKSDAKIKAQEEADKRKKEHERIMLQNLQERLERKKVWRSVTLRRPESLELSLPSGKKGTLSLPACTPSNKTHDSIASLRCILFINISFTHGLFRQKSCSQSSDWFAIICA", "length": 767, "header": "tr|G3MZK6-1|G3MZK6_BOVIN Isoform 1 of MAP7 domain containing 3 OS=Bos taurus OX=9913 GN=MAP7D3 PE=3 SV=4 CANONICAL=G3MZK6-1" }, "locus": { "chromosome": "NKLS02002208.1", "start_pos": 8679614, "end_pos": 8655798, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000064329.4", "url": "https://www.ensembl.org/id/ENSBTAT00000064329.4" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000055006.4", "url": "https://www.ensembl.org/id/ENSBTAP00000055006.4" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [], "orthologs": [], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 1, "go_terms": [ { "name": "microtubule cytoskeleton", "id": "GO:0015630", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0015630", "evidence": [ { "database": "UniProtKB", "id": "G3MZK6", "url": "https://www.uniprot.org/uniprotkb/G3MZK6" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 1, "go_terms": [ { "name": "microtubule cytoskeleton organization", "id": "GO:0000226", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000226", "evidence": [ { "database": "UniProtKB", "id": "G3MZK6", "url": "https://www.uniprot.org/uniprotkb/G3MZK6" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 176, "end_pos": 178, "annotation": "n_glycosylation_sequon" }, { "start_pos": 555, "end_pos": 557, "annotation": "n_glycosylation_sequon" }, { "start_pos": 726, "end_pos": 728, "annotation": "n_glycosylation_sequon" }, { "start_pos": 742, "end_pos": 744, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [ { "pdb_id": "AF-G3MZK6-F1", "pdb_chain": "global", "start_pos": 1, "end_pos": 767, "overlap": "1.0", "method": "AlphaFold", "type": "alphafold", "resolution": -1.0, "url": "https://data.glygen.org/ln2downloads/pdb/current/AF-G3MZK6-F1.pdb", "url_external": "https://alphafold.ebi.ac.uk/entry/G3MZK6" } ], "lectin_list": [], "domain_list": [], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 176, "end_pos": 178 }, { "start_pos": 555, "end_pos": 557 }, { "start_pos": 726, "end_pos": 728 }, { "start_pos": 742, "end_pos": 744 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ], "tool_support": { "graph_view": "yes" } }, { "uniprot_canonical_ac": "G3N0X3-1", "uniprot_ac": "G3N0X3", "uniprot_id": "G3N0X3_BOVIN", "mass": { "chemical_mass": 53634.0, "monoisotopic_mass": 53634.0 }, "refseq": { "ac": "XP_024848632", "name": "interleukin-17 receptor E-like protein isoform X5", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_024848632" }, "gene_names": [ { "name": "IL17REL", "type": "recommended", "evidence": [ { "id": "G3N0X3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3N0X3" } ] }, { "name": "IL17REL", "type": "synonym", "evidence": [ { "id": "XP_024848632", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_024848632" } ] } ], "protein_names": [ { "name": "Interleukin 17 receptor E like", "type": "synonym", "evidence": [ { "id": "G3N0X3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3N0X3/entry#names_and_taxonomy" } ] }, { "name": "interleukin-17 receptor E-like protein isoform X5", "type": "synonym", "evidence": [ { "id": "XP_024848632", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_024848632" } ] } ], "function": [], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Bos taurus", "taxid": 9913, "evidence": [ { "database": "UniProtKB", "id": "G3N0X3", "url": "https://www.uniprot.org/uniprotkb/G3N0X3" } ], "common_name": "Bovine", "glygen_name": "Bovine", "reference_species": "Bos taurus [9913]" } ], "gene": [ { "name": "IL17REL", "url": "https://www.uniprot.org/uniprotkb/G3N0X3", "locus": { "chromosome": "5", "start_pos": 119368226, "end_pos": 119390140, "strand": "+", "evidence": [ { "database": "Ensembl Gene", "id": "ENSBTAG00000045808", "url": "https://www.ensembl.org/id/ENSBTAG00000045808" } ] } } ], "crossref": [ { "id": "G3N0X3", "url": "https://alphafold.ebi.ac.uk/entry/G3N0X3", "database": "AlphaFoldDB", "categories": [] }, { "id": "ENSBTAG00000045808", "url": "https://bgee.org/?page=gene&gene_id=ENSBTAG00000045808", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "100336471", "url": "https://www.ncbi.nlm.nih.gov/gene/100336471", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR027841", "url": "https://www.ebi.ac.uk/interpro/entry/IPR027841", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR039465", "url": "https://www.ebi.ac.uk/interpro/entry/IPR039465", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "bta:100336471", "url": "https://www.genome.jp/dbget-bin/www_bget?bta:100336471", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "CSQGLQC", "url": "https://omabrowser.org/oma/group/CSQGLQC/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "PTHR15583", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR15583", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR15583:SF10", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR15583:SF10", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF15037", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF15037", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "XP_024848632", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_024848632", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0AAA9S058", "url": "https://www.uniprot.org/uniprotkb/A0AAA9S058", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0AAA9S058-1", "url": "https://www.uniprot.org/uniprotkb/A0AAA9S058-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0AAA9SPE2", "url": "https://www.uniprot.org/uniprotkb/A0AAA9SPE2", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0AAA9SPE2-1", "url": "https://www.uniprot.org/uniprotkb/A0AAA9SPE2-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "G3N0X3", "url": "https://www.uniprot.org/uniprotkb/G3N0X3", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "G3N0X3-1", "url": "https://www.uniprot.org/uniprotkb/G3N0X3-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MLAGHAVALLCLTWGAYQSLAIPRVTECGLSCPQGFACKSLVSRGNIFNSFCQQPPASMPRSVLGALGLSTAMKCSPPDGCSLLLRVNASLTFHESLQGLEVCSTSLDTQETQCQTVQVPRASHRQAGQQLQVRFDCFKVGVAQSLYVTLRTVPHFCGVQLGQQYHTEDCREEDVGKNVPDCFAQKLSYWVDRSRKVILVQVPESGGPDYYVRLCLKRFICEDAGAPVRVIGNRVSRRVSLPYSQELSCLCLEVWSATPDAVRIQTCPFKNDTESLWDAIRYHPGSQALSWEPACPMRGRVSLCWQPGPGAHCLELKHSGRPARGRVQYPLVDTQPQLCLKFSTSLGFQVRCPFKQPRFPAWKMAVQPAPAPGRLRVAFFSSGPARFQVRLCHQGKTWPPACRRLLQATPVPAASVSQGDSAEDPAVAFVDIPGDEACAPSTCIQGRRTDVQFSVPQQLCNLQCGWRGHTAQEVEDRGATASAPGQASEP", "length": 490, "header": "tr|G3N0X3-1|G3N0X3_BOVIN Isoform 1 of Interleukin 17 receptor E like OS=Bos taurus OX=9913 GN=IL17REL PE=4 SV=2 CANONICAL=G3N0X3-1" }, "isoforms": [ { "isoform_ac": "A0AAA9S058-1", "url": "https://www.uniprot.org/uniprotkb/A0AAA9S058/entry", "sequence": { "sequence": "MLAGHAVALLCLTWGAYQSLAIPRVTECGLSCPQGFACKSLVSRGNIFNSFCQQPPASMPRSVLGALGLSTAMKCSPPDGCSLLLRVNASLTFHESLQGLEVCSTSLDTQETQCQTVQVPRASHRQAGQQLQVRFDCFKVGVAQSLYVTLRTVPHFCGVQLGQQYHTEDCREEDVGKNVPDCFAQKLSYWVDRSRKVILVQVPESGGPDYYVRLCLKRFICEDAGAPVRVIGNRVSRRVSLPYSQELSCLCLEVWSATPDAVRIQTCPFKNDTESLWDAIRYHPGSQALSWEPACPMRGRVSLCWQPGPGAHCLELKHSGRPARGRVQYPLVDTQPQLCLKPGRWPSSPHPLPAASGWPSSRPAPPGSRCACVTRGRRGPPPAVDCSRPPPSLRPL", "length": 396, "header": "tr|A0AAA9S058-1|G3N0X3_BOVIN Computationally mapped isoform of Interleukin 17 receptor E like OS=Bos taurus OX=9913 GN=IL17REL PE=4 SV=1 CANONICAL=G3N0X3-1" }, "locus": { "chromosome": "5", "start_pos": 119390045, "end_pos": 119368924, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000095647.1", "url": "https://www.ensembl.org/id/ENSBTAT00000095647.1" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000077010.1", "url": "https://www.ensembl.org/id/ENSBTAP00000077010.1" } ] } }, { "isoform_ac": "A0AAA9SPE2-1", "url": "https://www.uniprot.org/uniprotkb/A0AAA9SPE2/entry", "sequence": { "sequence": "MLAGHAVALLCLTWGAYQSLAIPRVTECGLSCPQGFACKSLVSRESLQGLEVCSTSLDTQETQCQTVQVPRASHRQAGQQLQVRFDCFKVGVAQSLYVTLRTVPHFCGVQLGQQYHTEDCREEDVGKNVPDCFAQKLSYWVDRSRKVILVQVPESGGPDYYVRLCLKRFICEDAGAPVRVIGNRVSRRVSLPYSQELSCLCLEVWSATPDAVRIQTCPFKNDTESLWDAIRYHPGSQALSWEPACPMRGRVSLCWQPGPGAHCLELKHSGRPARGRVQYPLVDTQPQLCLKFSTSLGFQVRCPFKQPRFPAWKMAVQPAPAPGRLRVAFFSSGPARFQVRLCHQGKTWPPACRRLLQATPVPAASVSQGDSAEDPAVAFVDIPGDEACAPSTCIQGRRTDVQFSVPQQLCNLQCGWRGHTAQEVEDRGATASAPGQASEP", "length": 440, "header": "tr|A0AAA9SPE2-1|G3N0X3_BOVIN Computationally mapped isoform of Interleukin 17 receptor E like OS=Bos taurus OX=9913 GN=IL17REL PE=4 SV=1 CANONICAL=G3N0X3-1" }, "locus": { "chromosome": "5", "start_pos": 119390045, "end_pos": 119368234, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000112393.1", "url": "https://www.ensembl.org/id/ENSBTAT00000112393.1" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000085799.1", "url": "https://www.ensembl.org/id/ENSBTAP00000085799.1" } ] } }, { "isoform_ac": "G3N0X3-1", "url": "https://www.uniprot.org/uniprotkb/G3N0X3/entry", "sequence": { "sequence": "MLAGHAVALLCLTWGAYQSLAIPRVTECGLSCPQGFACKSLVSRGNIFNSFCQQPPASMPRSVLGALGLSTAMKCSPPDGCSLLLRVNASLTFHESLQGLEVCSTSLDTQETQCQTVQVPRASHRQAGQQLQVRFDCFKVGVAQSLYVTLRTVPHFCGVQLGQQYHTEDCREEDVGKNVPDCFAQKLSYWVDRSRKVILVQVPESGGPDYYVRLCLKRFICEDAGAPVRVIGNRVSRRVSLPYSQELSCLCLEVWSATPDAVRIQTCPFKNDTESLWDAIRYHPGSQALSWEPACPMRGRVSLCWQPGPGAHCLELKHSGRPARGRVQYPLVDTQPQLCLKFSTSLGFQVRCPFKQPRFPAWKMAVQPAPAPGRLRVAFFSSGPARFQVRLCHQGKTWPPACRRLLQATPVPAASVSQGDSAEDPAVAFVDIPGDEACAPSTCIQGRRTDVQFSVPQQLCNLQCGWRGHTAQEVEDRGATASAPGQASEP", "length": 490, "header": "tr|G3N0X3-1|G3N0X3_BOVIN Isoform 1 of Interleukin 17 receptor E like OS=Bos taurus OX=9913 GN=IL17REL PE=4 SV=2 CANONICAL=G3N0X3-1" }, "locus": { "chromosome": "5", "start_pos": 119390045, "end_pos": 119368234, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000066270.3", "url": "https://www.ensembl.org/id/ENSBTAT00000066270.3" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000055493.2", "url": "https://www.ensembl.org/id/ENSBTAP00000055493.2" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [ { "id": "bta:100336471", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?bta:100336471", "resource": "KEGG Pathway" } ], "orthologs": [ { "uniprot_canonical_ac": "A0A5G2QU96-1", "protein_name": "Interleukin 17 receptor E like", "gene_name": "IL17REL", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MLTGQAVALLSLTWSAYQSLAVPRVSECGLSCSQGFTCKSRVNRNIFNSFCQQPPTSMSRSVLEALALSTAMKCSPPDGCALLLRVQASLMPHESLRGLEACSVSLDTQETQCQSVRIRRASRRLQRGQQLQVHFDCFEVGVAQSLYVTLRTVPHFCGIQLDQQYQVEAGKLSYWVARSHKVVLVQVPEAPGGPDYYVRLCLKRFTCEEAGAPVRVTADGVSRRVSLPYSQELPCLCLEAWPATPDAVRIQACPFKDDTETLWDAVYYQPGSQALSWEPPCPVSGHVSLCWRPGPGAPCLELEHSGRPAHGRVRYPLVDAQPQLCLKFSTSLGVRLRCPFQQLGFPALPASRCACVTKEGRGPRPAAECSRPLPSLQPQVTPRRSLWRPSWTFPRTRPVRPAPASRSGGLMPTSRPPSSCVTFRALPPRGQQPEARCLAKKKQAPGPDGGAVERGQLTPGPQALTQRPGLAWPLTVGPVALPELQRLWLHRAPWARHGFRSDEGPSAPPKPLSGRQLNGCPGCPLPQRAQPLTCPISARSRLPLDNQGQGLECGVWAHPFCS", "length": 562 }, "evidence": [ { "id": "G3N0X3", "url": "https://omabrowser.org/oma/group/G3N0X3/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "A0A8V0XVL9-1", "protein_name": "Interleukin 17 receptor E like", "gene_name": "IL17REL", "tax_id": 9031, "organism": "Gallus gallus", "sequence": { "sequence": "MISVHVLILLIILFWNYDCHIIPRIEECGLSCSQGIHCKSKPSSGIFNSFCHSAPASLSSMVLKSMKISTVIKCPQGSPCSLHLNIKGTLSLDENIRGLEICSFSLDTQQSQCTNVRFARKKNKILNGKKVQVQFNCFEVNVAQHIYVTVKTVPNYCEVKMSQEYYVEDCRNSDVGKHIPACLAGKLDYNVDRTRKIISVNVSNFLRDQDYYIRLCHKWFTCEDVGQFAVIKGKDSLKSVSLKYSQLLPCLCIEGWLAIPDARRLQLCPFENDTKALWDNIVYNPVTQTLAWEPACPVLVIVNLCRLMKSNDHCEDIQDSSKRFPEKQVKYSRVDTHPRLCMKFTTKQGSWVKCPFAHGEFPAWKMRTAAVADRIQVFFTSQTKAHFSVLVCNRTQLASCESVGMRHSVSVGDSVSIMMSREMCGSTICIQGWRTDVDYSVPLQTCDIHCGFRGQTYGNENPAKALTHRMKSVHSLH", "length": 477 }, "evidence": [ { "id": "G3N0X3", "url": "https://omabrowser.org/oma/group/G3N0X3/", "database": "OMA" } ], "glygen_name": "Chicken", "common_name": "Chicken" }, { "uniprot_canonical_ac": "Q6ZVW7-1", "protein_name": "Interleukin-17 receptor E-like protein", "gene_name": "IL17REL", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MLAGQALAFLGLTWGTFQSLAIPRITECGLSCSQGFACRSHRNRNIFNSFCRPRPVSMSRSVLEALTSSTAMQCVPSDGCAMLLRVRASITLHERLRGLEACAMSLDTQETQCQSVWVARASHRQQGGQQLQVHFGCFAVSVAQHLYVTLRTIPHFCGVQLDQRHLVEDCGEEDVGRSVPDCLAGKLSYWVDRRRKAILVQVPRASGSPDYYLRLCLKRFTCEDAGAPVRVTANSVSQAVFLPYSQELPCLCLEGWSATPDAVRIQICPFENDTEALEVLWDTVYYHPESQTLSWEPACPVSGHVSLCWRPGPGAGCRKLQQSSQLVHRRVQYPLVDTQPQLCLKFSTSWGSWVRCPFEQRRFPTWKMTIQPSPTKGHLRVTFFSSSPAHFQVHLCHRRKSQLPACQRTLQASPLPSASGDLAAAPAFAFLDLPREEACAPGICIQGWRTDVHFSVPQQLCNLRSSGCPSLRGRRRPRTRPRPPTAGWAWRALNRRLGGGNGETIRP", "length": 507 }, "evidence": [ { "id": "G3N0X3", "url": "https://omabrowser.org/oma/group/G3N0X3/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" } ], "go_annotation": { "categories": [ { "name": "Molecular Function", "total": 1, "go_terms": [ { "name": "interleukin-17 receptor activity", "id": "GO:0030368", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030368", "evidence": [ { "database": "UniProtKB", "id": "G3N0X3", "url": "https://www.uniprot.org/uniprotkb/G3N0X3" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 271, "end_pos": 273, "annotation": "n_glycosylation_sequon" }, { "start_pos": 88, "end_pos": 90, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [ { "pdb_id": "AF-G3N0X3-F1", "pdb_chain": "global", "start_pos": 1, "end_pos": 490, "overlap": "1.0", "method": "AlphaFold", "type": "alphafold", "resolution": -1.0, "url": "https://data.glygen.org/ln2downloads/pdb/current/AF-G3N0X3-F1.pdb", "url_external": "https://alphafold.ebi.ac.uk/entry/G3N0X3" } ], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "G3N0X3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3N0X3" }, { "id": "PF15037", "database": "Pfam", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF15037" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "Interleukin-17 receptor C/E N-terminal", "eco_id": "ECO_0000259", "start_pos": 107, "end_pos": 361, "start_aa": "Leu", "end_aa": "Ala", "glycosite_overlap": [] } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" }, { "name": "homologset.oma", "label": "OMA Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 271, "end_pos": 273 }, { "start_pos": 88, "end_pos": 90 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ], "tool_support": { "graph_view": "yes" } }, { "uniprot_canonical_ac": "G3N2K8-1", "uniprot_ac": "G3N2K8", "uniprot_id": "G3N2K8_BOVIN", "mass": { "chemical_mass": 26762.0, "monoisotopic_mass": 26762.0 }, "refseq": { "ac": "XP_005220225", "name": "uncharacterized protein C17orf107 homolog isoform X1", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_005220225" }, "gene_names": [ { "name": "C19H17orf107", "type": "recommended", "evidence": [ { "id": "G3N2K8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3N2K8" } ] }, { "name": "C19H17orf107", "type": "synonym", "evidence": [ { "id": "XP_005220225", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_005220225" } ] } ], "protein_names": [ { "name": "Chromosome 19 C17orf107 homolog", "type": "synonym", "evidence": [ { "id": "G3N2K8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3N2K8/entry#names_and_taxonomy" } ] }, { "name": "uncharacterized protein C17orf107 homolog isoform X1", "type": "synonym", "evidence": [ { "id": "XP_005220225", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_005220225" } ] } ], "function": [], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Bos taurus", "taxid": 9913, "evidence": [ { "database": "UniProtKB", "id": "G3N2K8", "url": "https://www.uniprot.org/uniprotkb/G3N2K8" } ], "common_name": "Bovine", "glygen_name": "Bovine", "reference_species": "Bos taurus [9913]" } ], "gene": [ { "name": "C19H17orf107", "url": "https://www.uniprot.org/uniprotkb/G3N2K8", "locus": { "chromosome": "19", "start_pos": 26487252, "end_pos": 26488520, "strand": "+", "evidence": [ { "database": "Ensembl Gene", "id": "ENSBTAG00000047992", "url": "https://www.ensembl.org/id/ENSBTAG00000047992" } ] } } ], "crossref": [ { "id": "G3N2K8", "url": "https://alphafold.ebi.ac.uk/entry/G3N2K8", "database": "AlphaFoldDB", "categories": [] }, { "id": "ENSBTAG00000047992", "url": "https://bgee.org/?page=gene&gene_id=ENSBTAG00000047992", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "100137824", "url": "https://www.ncbi.nlm.nih.gov/gene/100137824", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR038963", "url": "https://www.ebi.ac.uk/interpro/entry/IPR038963", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "G3N2K8", "url": "https://www.orthodb.org/?gene=G3N2K8", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR38506", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR38506", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR38506:SF1", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR38506:SF1", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF17688", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF17688", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "XP_005220225", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_005220225", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0AAA9S088", "url": "https://www.uniprot.org/uniprotkb/A0AAA9S088", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0AAA9S088-1", "url": "https://www.uniprot.org/uniprotkb/A0AAA9S088-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0AAA9TRW6", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TRW6", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0AAA9TRW6-1", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TRW6-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "G3N2K8", "url": "https://www.uniprot.org/uniprotkb/G3N2K8", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "G3N2K8-1", "url": "https://www.uniprot.org/uniprotkb/G3N2K8-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MSHRAATGPLTSQTHLSAGVELLLAGPDGPPPGPVFLPALARPVATMKGTPSSLETLLWVYHFHSSTEVALQPPLLSSLELVAAAAHEYLEQRFRELKSLEPREPENPPARKPTLGLVLREAAASVVNFGATLLEISALWVQQELRRLDGGPGPGPDAGDPGGALARVAQAAGQGALQVGAAAGASARLLLQGAWLCLCGRGLQGSASFLQQWQRHLDLGTPGEPRYSGGLKLASSSTAEDGGPKNPPRSQPRPTSK", "length": 257, "header": "tr|G3N2K8-1|G3N2K8_BOVIN Isoform 1 of Chromosome 19 C17orf107 homolog OS=Bos taurus OX=9913 GN=C19H17orf107 PE=4 SV=2 CANONICAL=G3N2K8-1" }, "isoforms": [ { "isoform_ac": "A0AAA9S088-1", "url": "https://www.uniprot.org/uniprotkb/A0AAA9S088/entry", "sequence": { "sequence": "MKGTPSSLETLLWVYHFHSSTEVALQPPLLSSLELVAAAAHEYLEQRFRELKSLEPREPENPPARKPTLGLVLREAAASVVNFGATLLEVGRRGAGRRRGSRERGSRSRDLCIPTNFCIPTTDLSPVGAAGATATRRRPGSGPRRWGSGWSPGPGSPGRGAGGSASGGCSRRERPAPAPGGLAMPVWTRSAGVSLIPATVATPSGPRNPWGTGEFKMRGELGARGVPAGWH", "length": 231, "header": "tr|A0AAA9S088-1|G3N2K8_BOVIN Computationally mapped isoform of Chromosome 19 C17orf107 homolog OS=Bos taurus OX=9913 GN=C19H17orf107 PE=4 SV=1 CANONICAL=G3N2K8-1" }, "locus": { "chromosome": "19", "start_pos": 26488183, "end_pos": 26487380, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000109143.1", "url": "https://www.ensembl.org/id/ENSBTAT00000109143.1" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000076740.1", "url": "https://www.ensembl.org/id/ENSBTAP00000076740.1" } ] } }, { "isoform_ac": "A0AAA9TRW6-1", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TRW6/entry", "sequence": { "sequence": "MSHRAATGPLTSQTHLSAGVELLLAGPDGPPPGPVFLPALARPVATMKGTPSSLETLLWVYHFHSSTEVALQPPLLSSLELVAAAAHEYLEQRFRELKSLEPREPENPPARKPTLGLVLREAAASVVNFGATLLEISALWVQQELRRLDGGPGPGPDAGDPGGALARVAQAAGQGALQVGAAAGASARLLLQGAWLCLCGRGLQGSASFLQQWQRHLDLGTPGEPVSSR", "length": 229, "header": "tr|A0AAA9TRW6-1|G3N2K8_BOVIN Computationally mapped isoform of Chromosome 19 C17orf107 homolog OS=Bos taurus OX=9913 GN=C19H17orf107 PE=4 SV=1 CANONICAL=G3N2K8-1" }, "locus": { "chromosome": "19", "start_pos": 26488321, "end_pos": 26487424, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000094453.1", "url": "https://www.ensembl.org/id/ENSBTAT00000094453.1" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000099217.1", "url": "https://www.ensembl.org/id/ENSBTAP00000099217.1" } ] } }, { "isoform_ac": "G3N2K8-1", "url": "https://www.uniprot.org/uniprotkb/G3N2K8/entry", "sequence": { "sequence": "MSHRAATGPLTSQTHLSAGVELLLAGPDGPPPGPVFLPALARPVATMKGTPSSLETLLWVYHFHSSTEVALQPPLLSSLELVAAAAHEYLEQRFRELKSLEPREPENPPARKPTLGLVLREAAASVVNFGATLLEISALWVQQELRRLDGGPGPGPDAGDPGGALARVAQAAGQGALQVGAAAGASARLLLQGAWLCLCGRGLQGSASFLQQWQRHLDLGTPGEPRYSGGLKLASSSTAEDGGPKNPPRSQPRPTSK", "length": 257, "header": "tr|G3N2K8-1|G3N2K8_BOVIN Isoform 1 of Chromosome 19 C17orf107 homolog OS=Bos taurus OX=9913 GN=C19H17orf107 PE=4 SV=2 CANONICAL=G3N2K8-1" }, "locus": { "chromosome": "19", "start_pos": 26488321, "end_pos": 26487262, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000064961.3", "url": "https://www.ensembl.org/id/ENSBTAT00000064961.3" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000056123.2", "url": "https://www.ensembl.org/id/ENSBTAP00000056123.2" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [], "orthologs": [], "go_annotation": {}, "pro_annotation": [], "site_annotation": [], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [ { "pdb_id": "AF-G3N2K8-F1", "pdb_chain": "global", "start_pos": 1, "end_pos": 257, "overlap": "1.0", "method": "AlphaFold", "type": "alphafold", "resolution": -1.0, "url": "https://data.glygen.org/ln2downloads/pdb/current/AF-G3N2K8-F1.pdb", "url_external": "https://alphafold.ebi.ac.uk/entry/G3N2K8" } ], "lectin_list": [], "domain_list": [], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ], "tool_support": { "graph_view": "yes" } }, { "uniprot_canonical_ac": "G3MYW6-1", "uniprot_ac": "G3MYW6", "uniprot_id": "G3MYW6_BOVIN", "mass": { "chemical_mass": 29381.0, "monoisotopic_mass": 29381.0 }, "refseq": { "ac": "XP_002694765", "name": "V-set and transmembrane domain-containing protein 2B isoform X1", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_002694765" }, "gene_names": [ { "name": "VSTM2B", "type": "recommended", "evidence": [ { "id": "G3MYW6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3MYW6" } ] }, { "name": "VSTM2B", "type": "synonym", "evidence": [ { "id": "XP_002694765", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_002694765" } ] } ], "protein_names": [ { "name": "V-set and transmembrane domain-containing protein 2B", "type": "recommended", "evidence": [ { "id": "G3MYW6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3MYW6/entry#names_and_taxonomy" } ] }, { "name": "V-set and transmembrane domain-containing protein 2B isoform X1", "type": "synonym", "evidence": [ { "id": "XP_002694765", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_002694765" } ] } ], "function": [], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Bos taurus", "taxid": 9913, "evidence": [ { "database": "UniProtKB", "id": "G3MYW6", "url": "https://www.uniprot.org/uniprotkb/G3MYW6" } ], "common_name": "Bovine", "glygen_name": "Bovine", "reference_species": "Bos taurus [9913]" } ], "gene": [ { "name": "VSTM2B", "url": "https://www.uniprot.org/uniprotkb/G3MYW6", "locus": { "chromosome": "18", "start_pos": 1330650, "end_pos": 1301321, "strand": "-", "evidence": [ { "database": "Ensembl Gene", "id": "ENSBTAG00000018244", "url": "https://www.ensembl.org/id/ENSBTAG00000018244" } ] } } ], "crossref": [ { "id": "G3MYW6", "url": "https://alphafold.ebi.ac.uk/entry/G3MYW6", "database": "AlphaFoldDB", "categories": [] }, { "id": "ENSBTAG00000018244", "url": "https://bgee.org/?page=gene&gene_id=ENSBTAG00000018244", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "790185", "url": "https://www.ncbi.nlm.nih.gov/gene/790185", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR003599", "url": "https://www.ebi.ac.uk/interpro/entry/IPR003599", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR007110", "url": "https://www.ebi.ac.uk/interpro/entry/IPR007110", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR013106", "url": "https://www.ebi.ac.uk/interpro/entry/IPR013106", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR013783", "url": "https://www.ebi.ac.uk/interpro/entry/IPR013783", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR036179", "url": "https://www.ebi.ac.uk/interpro/entry/IPR036179", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR051102", "url": "https://www.ebi.ac.uk/interpro/entry/IPR051102", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "bta:790185", "url": "https://www.genome.jp/dbget-bin/www_bget?bta:790185", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "YQCRVSD", "url": "https://omabrowser.org/oma/group/YQCRVSD/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "G3MYW6", "url": "https://www.orthodb.org/?gene=G3MYW6", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR12207", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR12207", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR12207:SF27", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR12207:SF27", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF07686", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF07686", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "XP_002694765", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_002694765", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0AAA9S0K0", "url": "https://www.uniprot.org/uniprotkb/A0AAA9S0K0", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0AAA9S0K0-1", "url": "https://www.uniprot.org/uniprotkb/A0AAA9S0K0-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "G3MYW6", "url": "https://www.uniprot.org/uniprotkb/G3MYW6", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "G3MYW6-1", "url": "https://www.uniprot.org/uniprotkb/G3MYW6-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MEQRNRLGAPGYLPPLVLRALLLFVAEATFTEVPKDVTVREGDDIEMPCAFRASGATSYSLEIQWWYLKEPPRELLHELALSVPGARSKVTNKDATKISTVRVQGNDISHRLRLSAVRRQDEGVYECRVSDYSDDDTQEHTAQALLRVLARFAPPDVQAAEAVSHIQSGGPRRHGPASAARADGAQEPGRSDKSPPPGGPPAAPAPGVPEAAAASAAHRAATTVAAAASSAPPPPREAALLRQRHSGTGPNYTTDPLLSLFLLALHEFLHLLVGP", "length": 275, "header": "tr|G3MYW6-1|G3MYW6_BOVIN Isoform 1 of V-set and transmembrane domain-containing protein 2B OS=Bos taurus OX=9913 GN=VSTM2B PE=4 SV=2 CANONICAL=G3MYW6-1" }, "isoforms": [ { "isoform_ac": "A0AAA9S0K0-1", "url": "https://www.uniprot.org/uniprotkb/A0AAA9S0K0/entry", "sequence": { "sequence": "MEQRNRLGAPGYLPPLVLRALLLFVAEATFTEVPKDVTVREGDDIEMPCAFRASGATSYSLEIQWWYLKEPPRELLHELALSVPGARSKTVRVQGNDISHRLRLSAVRRQDEGVYECRVSDYSDDDTQEHTAQALLRVLARFAPPDVQAAEAVSHIQSGGPRRHGPASAARADGAQEPGRSDKSPPPGGPPAAPAPGVPEAAAASAAHRAATTVAAAASSAPPPPREAALLRQRHSGTGPNYTTDPLLSLFLLALHEFLHLLVGP", "length": 265, "header": "tr|A0AAA9S0K0-1|G3MYW6_BOVIN Computationally mapped isoform of V-set and transmembrane domain-containing protein 2B OS=Bos taurus OX=9913 GN=VSTM2B PE=4 SV=1 CANONICAL=G3MYW6-1" }, "locus": { "chromosome": "18", "start_pos": 1329646, "end_pos": 1301520, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000109638.1", "url": "https://www.ensembl.org/id/ENSBTAT00000109638.1" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000075588.1", "url": "https://www.ensembl.org/id/ENSBTAP00000075588.1" } ] } }, { "isoform_ac": "G3MYW6-1", "url": "https://www.uniprot.org/uniprotkb/G3MYW6/entry", "sequence": { "sequence": "MEQRNRLGAPGYLPPLVLRALLLFVAEATFTEVPKDVTVREGDDIEMPCAFRASGATSYSLEIQWWYLKEPPRELLHELALSVPGARSKVTNKDATKISTVRVQGNDISHRLRLSAVRRQDEGVYECRVSDYSDDDTQEHTAQALLRVLARFAPPDVQAAEAVSHIQSGGPRRHGPASAARADGAQEPGRSDKSPPPGGPPAAPAPGVPEAAAASAAHRAATTVAAAASSAPPPPREAALLRQRHSGTGPNYTTDPLLSLFLLALHEFLHLLVGP", "length": 275, "header": "tr|G3MYW6-1|G3MYW6_BOVIN Isoform 1 of V-set and transmembrane domain-containing protein 2B OS=Bos taurus OX=9913 GN=VSTM2B PE=4 SV=2 CANONICAL=G3MYW6-1" }, "locus": { "chromosome": "18", "start_pos": 1329646, "end_pos": 1301520, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000063809.3", "url": "https://www.ensembl.org/id/ENSBTAT00000063809.3" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000054755.2", "url": "https://www.ensembl.org/id/ENSBTAP00000054755.2" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [ { "id": "bta:790185", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?bta:790185", "resource": "KEGG Pathway" } ], "orthologs": [ { "uniprot_canonical_ac": "A6NLU5-1", "protein_name": "V-set and transmembrane domain-containing protein 2B", "gene_name": "VSTM2B", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MEQRNRLGALGYLPPLLLHALLLFVADAAFTEVPKDVTVREGDDIEMPCAFRASGATSYSLEIQWWYLKEPPRELLHELALSVPGARSKVTNKDATKISTVRVQGNDISHRLRLSAVRLQDEGVYECRVSDYSDDDTQEHKAQAMLRVLSRFAPPNMQAAEAVSHIQSSGPRRHGPASAANANNAGAASRTTSEPGRGDKSPPPGSPPAAIDPAVPEAAAASAAHTPTTTVAAAAAASSASPPSGQAVLLRQRHGSGTGRSYTTDPLLSLLLLALHKFLRLLLGH", "length": 285 }, "evidence": [ { "id": "G3MYW6", "url": "https://omabrowser.org/oma/group/G3MYW6/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "D4A3Q0-1", "protein_name": "V-set and transmembrane domain-containing protein 2B", "gene_name": "Vstm2b", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MEQRNRLGALGYLLPLLLHSLLLFVADATFTEVPKDVTVREGDDIEMPCAFRASGATSYSLEIQWWYLKEPPRELLHELALSVPGARSKVTNKDATKISTVRVQGNDISHRLRLSAVRLQDEGVYECRVSDYSDDDTQEHKAQALLRVLSRFTPPNMQAAEAVSHIQSSGPRRHGASSAVSSNNAGAALLTTSETSHDDKNPLPASPPSGSGVPEAAAAAAASATHKATTMASAAAASSSASPPSGQAVLLRQRHGSGTGPGYSADPLLSLLLLALHKFLHPLLGH", "length": 286 }, "evidence": [ { "id": "G3MYW6", "url": "https://omabrowser.org/oma/group/G3MYW6/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "I3LU35-1", "protein_name": "V-set and transmembrane domain-containing protein 2B", "gene_name": "VSTM2B", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MEQRNRLGALGYLPPLLLHALLLFVADATFTEVPKDVTVREGDDIEMPCAFRASGATSYSLEIQWWYLKEPPRELLHELALSVPGARSKVTNKDATKISTVRVQGNDISHRLRLSAVRRQDEGVYECRVSDYSDDDTQEHKAQALLRVLSRFAPPNMQAAEAVSHIQSSGPRRHGPASAASATNVGAVGRATSEPDRGDKSPPPGSPPVAPGPGIPEAAAAAAASAAHAATTTVAAAAAASSASPPPREAVLLRQRHGSGTGPNFATDPLLSLLLLALHKFLRLLVGP", "length": 288 }, "evidence": [ { "id": "G3MYW6", "url": "https://omabrowser.org/oma/group/G3MYW6/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "Q9JME9-1", "protein_name": "V-set and transmembrane domain-containing protein 2B", "gene_name": "Vstm2b", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MEQRNRLGALGYLLPLLLHSLLLFVADATFTEVPKDVTVREGDDIEMPCAFRASGATSYSLEIQWWYLKEPPRELLHELALSVPGARSKVTNKDATKISTVRVQGNDISHRLRLSAVRLQDEGVYECRVSDYSDDDTQEHKAQALLRVLSRFAPPNMQAAEAVSHIQSSGPRRHGASSAVSSNNAGAAVRTTSETSHDDKNPPPGSPPAGSGVPEAAAAAASATHTATTTAAAAAASSSASPPSGQAVLLRQRHGSGTGPGYSADPLLSLLLLALHKFLHPLLGH", "length": 285 }, "evidence": [ { "id": "G3MYW6", "url": "https://omabrowser.org/oma/group/G3MYW6/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" } ], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 1, "go_terms": [ { "name": "membrane", "id": "GO:0016020", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016020", "evidence": [ { "database": "UniProtKB", "id": "G3MYW6", "url": "https://www.uniprot.org/uniprotkb/G3MYW6" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 251, "end_pos": 253, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], 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} ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 251, "end_pos": 253 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": 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"database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "F6S0Z4-1", "url": "https://www.uniprot.org/uniprotkb/F6S0Z4-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MKSTKLNIKNGIFKKTIIPKVCLHQRKGGTILRSPPSSLDKHWGSERSFGSRTLQAERPAGKNPRSVEAAWACHVICALPDGKANAADSSFPRFGLGGSSCLQNMMASQLVKPDTRNCKRPRELEPQMPDSPQLSSLGKSDSSLSESSGLFYKDEALEKDLNDMSKEINLMLSTYAKILRQRAAVDASYIDEIDGLFKEANTIENFLIQKRELLRQRLTVIANTLHR", "length": 227, "header": "tr|F6S0Z4-1|F6S0Z4_BOVIN Isoform 1 of Testis expressed 12 OS=Bos taurus OX=9913 GN=TEX12 PE=4 SV=2 CANONICAL=F6S0Z4-1" }, "isoforms": [ { "isoform_ac": "A0AAA9S0K9-1", "url": "https://www.uniprot.org/uniprotkb/A0AAA9S0K9/entry", "sequence": { "sequence": "MMASQLVKPDTRNCKRPRELEPQMPDSPQLSSLGKSDSSLSESSGLFYKDEALEKDLNDIEVFFWKLHNGKFSSGSKKPICERAAVDASYIDEIDGLFKEANTIENFLIQKRELLRQRLTVIANTLHR", "length": 128, "header": "tr|A0AAA9S0K9-1|F6S0Z4_BOVIN Computationally mapped isoform of Testis expressed 12 OS=Bos taurus OX=9913 GN=TEX12 PE=4 SV=1 CANONICAL=F6S0Z4-1" }, "locus": { "chromosome": "15", "start_pos": 22508679, "end_pos": 22506730, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000094964.1", "url": "https://www.ensembl.org/id/ENSBTAT00000094964.1" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000079389.1", "url": "https://www.ensembl.org/id/ENSBTAP00000079389.1" } ] } }, { "isoform_ac": "F6S0Z4-1", "url": "https://www.uniprot.org/uniprotkb/F6S0Z4/entry", "sequence": { "sequence": "MKSTKLNIKNGIFKKTIIPKVCLHQRKGGTILRSPPSSLDKHWGSERSFGSRTLQAERPAGKNPRSVEAAWACHVICALPDGKANAADSSFPRFGLGGSSCLQNMMASQLVKPDTRNCKRPRELEPQMPDSPQLSSLGKSDSSLSESSGLFYKDEALEKDLNDMSKEINLMLSTYAKILRQRAAVDASYIDEIDGLFKEANTIENFLIQKRELLRQRLTVIANTLHR", "length": 227, "header": "tr|F6S0Z4-1|F6S0Z4_BOVIN Isoform 1 of Testis expressed 12 OS=Bos taurus OX=9913 GN=TEX12 PE=4 SV=2 CANONICAL=F6S0Z4-1" }, "locus": { "chromosome": "15", "start_pos": 22508679, "end_pos": 22504229, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000022009.5", "url": "https://www.ensembl.org/id/ENSBTAT00000022009.5" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000022009.5", "url": "https://www.ensembl.org/id/ENSBTAP00000022009.5" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [], "orthologs": [], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 1, "go_terms": [ { "name": "central element", "id": "GO:0000801", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000801", "evidence": [ { "database": "UniProtKB", "id": "F6S0Z4", "url": "https://www.uniprot.org/uniprotkb/F6S0Z4" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 1, "go_terms": [ { "name": "synaptonemal complex assembly", "id": "GO:0007130", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007130", "evidence": [ { "database": "UniProtKB", "id": "F6S0Z4", "url": "https://www.uniprot.org/uniprotkb/F6S0Z4" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [ { "pdb_id": "AF-F6S0Z4-F1", "pdb_chain": "global", "start_pos": 1, "end_pos": 227, "overlap": "1.0", "method": "AlphaFold", "type": "alphafold", "resolution": -1.0, "url": "https://data.glygen.org/ln2downloads/pdb/current/AF-F6S0Z4-F1.pdb", "url_external": "https://alphafold.ebi.ac.uk/entry/F6S0Z4" } ], "lectin_list": [], "domain_list": [], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": 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0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ], "tool_support": { "graph_view": "yes" } }, { "uniprot_canonical_ac": "G3MYN5-1", "uniprot_ac": "G3MYN5", "uniprot_id": "G3MYN5_BOVIN", "mass": { "chemical_mass": 21673.0, "monoisotopic_mass": 21673.0 }, "refseq": {}, "gene_names": [ { "name": "TNNI1", "type": "recommended", "evidence": [ { "id": "G3MYN5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3MYN5" } ] } ], "protein_names": [ { "name": "Troponin I, cardiac muscle", "type": "recommended", "evidence": [ { "id": "G3MYN5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3MYN5/entry#names_and_taxonomy" } ] }, { "name": "Cardiac troponin I", "type": "synonym", "evidence": [ { "id": "G3MYN5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3MYN5/entry#names_and_taxonomy" } ] } ], "function": [ { "annotation": "Troponin I is the inhibitory subunit of troponin, the thin filament regulatory complex which confers calcium-sensitivity to striated muscle actomyosin ATPase activity.", "evidence": [ { "database": "UniProtKB", "id": "A0AAA9SSK8", "url": "https://www.uniprot.org/uniprotkb/A0AAA9SSK8#function" }, { "database": "UniProtKB", "id": "ARBA00001988", "url": "https://www.uniprot.org/uniprotkb/ARBA00001988#function" }, { "database": "UniProtKB", "id": "A0AAA9S0V0", "url": "https://www.uniprot.org/uniprotkb/A0AAA9S0V0#function" }, { "database": "UniProtKB", "id": "G3MYN5", "url": "https://www.uniprot.org/uniprotkb/G3MYN5#function" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Bos taurus", "taxid": 9913, "evidence": [ { "database": "UniProtKB", "id": "G3MYN5", "url": "https://www.uniprot.org/uniprotkb/G3MYN5" } ], "common_name": "Bovine", "glygen_name": "Bovine", "reference_species": "Bos taurus [9913]" } ], "gene": [ { "name": "TNNI1", "url": "https://www.uniprot.org/uniprotkb/G3MYN5", "locus": { "chromosome": "16", "start_pos": 80906695, "end_pos": 80900873, "strand": "-", "evidence": [ { "database": "Ensembl Gene", "id": 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"Protein" ] }, { "id": "G3MYN5", "url": "https://www.uniprot.org/uniprotkb/G3MYN5", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "G3MYN5-1", "url": "https://www.uniprot.org/uniprotkb/G3MYN5-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MPEVERKPKITASRKLLLKSLMLAKAKECWEQEHEEREAEKKRYLAERIPALQTRGLSLSALQDLCRDLHAKVEVVDEERYDIEAKCLHNTREIKDLKLKVLDLRGKFKRPPLRRVRVSADAMLRALLGSKHKVSMDLRANLKSVKKEDTEKERPVEVGDWRKNVEAMSGMEGRKKMFDAAKSPTTQ", "length": 187, "header": "tr|G3MYN5-1|G3MYN5_BOVIN Isoform 1 of Troponin I, cardiac muscle OS=Bos taurus OX=9913 GN=TNNI1 PE=3 SV=3 CANONICAL=G3MYN5-1" }, "isoforms": [ { "isoform_ac": "A0AAA9S0V0-1", "url": "https://www.uniprot.org/uniprotkb/A0AAA9S0V0/entry", "sequence": { "sequence": "MPEVERKPKITASRKLLLKSLMLAKAKECWEQEHEEREAEKKRYLAERIPALQTRGLSLSALQDLCRDLHAKVEVVDEERYDIEAMSGMEGRKKMFDAAKSPTTQ", "length": 105, "header": "tr|A0AAA9S0V0-1|G3MYN5_BOVIN Computationally mapped isoform of Troponin I, cardiac muscle OS=Bos taurus OX=9913 GN=TNNI1 PE=3 SV=1 CANONICAL=G3MYN5-1" }, "locus": { "chromosome": "16", "start_pos": 80906690, "end_pos": 80900873, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000126839.1", "url": "https://www.ensembl.org/id/ENSBTAT00000126839.1" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000075700.1", "url": "https://www.ensembl.org/id/ENSBTAP00000075700.1" } ] } }, { "isoform_ac": "A0AAA9SSK8-1", "url": "https://www.uniprot.org/uniprotkb/A0AAA9SSK8/entry", "sequence": { "sequence": "MALLPVPVACPHPHGPVPACPHPRGLPPSPWPCPSLSPRASPLSPWPCPSLSPWSVPVACPPSPWSPPQEAEHCPHLLCFLLPSAPGLLVTDAHSERKPKITASRKLLLKSLMLAKAKECWEQEHEEREAEKKRYLAERIPALQTRGLSLSALQDLCRDLHAKVEVVDEERYDIEAKCLHNTREIKDLKLKVLDLRGKFKRPPLRRVRVSADAMLRALLGSKHKVSMDLRANLKSVKKEDTEKERPVEVGDWRKNVEAMSGMEGRKKMFDAAKSPTTQ", "length": 278, "header": "tr|A0AAA9SSK8-1|G3MYN5_BOVIN Computationally mapped isoform of Troponin I, cardiac muscle OS=Bos taurus OX=9913 GN=TNNI1 PE=3 SV=1 CANONICAL=G3MYN5-1" }, "locus": { "chromosome": "16", "start_pos": 80906690, "end_pos": 80901386, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000120948.2", "url": "https://www.ensembl.org/id/ENSBTAT00000120948.2" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000086979.1", "url": "https://www.ensembl.org/id/ENSBTAP00000086979.1" } ] } }, { "isoform_ac": "G3MYN5-1", "url": "https://www.uniprot.org/uniprotkb/G3MYN5/entry", "sequence": { "sequence": "MPEVERKPKITASRKLLLKSLMLAKAKECWEQEHEEREAEKKRYLAERIPALQTRGLSLSALQDLCRDLHAKVEVVDEERYDIEAKCLHNTREIKDLKLKVLDLRGKFKRPPLRRVRVSADAMLRALLGSKHKVSMDLRANLKSVKKEDTEKERPVEVGDWRKNVEAMSGMEGRKKMFDAAKSPTTQ", "length": 187, "header": "tr|G3MYN5-1|G3MYN5_BOVIN Isoform 1 of Troponin I, cardiac muscle OS=Bos taurus OX=9913 GN=TNNI1 PE=3 SV=3 CANONICAL=G3MYN5-1" }, "locus": { "chromosome": "16", "start_pos": 80906690, "end_pos": 80900873, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000063025.4", "url": "https://www.ensembl.org/id/ENSBTAT00000063025.4" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000054671.3", "url": "https://www.ensembl.org/id/ENSBTAP00000054671.3" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [ { "id": "R-BTA-390522", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-BTA-390522", "resource": "Reactome", "description": "Striated Muscle Contraction" } ], "orthologs": [], "go_annotation": { "categories": [ { "name": "Molecular Function", "total": 1, "go_terms": [ { "name": "actin binding", "id": "GO:0003779", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003779", "evidence": [ { "database": "UniProtKB", "id": "G3MYN5", "url": "https://www.uniprot.org/uniprotkb/G3MYN5" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 1, "go_terms": [ { "name": "troponin complex", "id": "GO:0005861", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005861", "evidence": [ { "database": "UniProtKB", "id": "G3MYN5", "url": "https://www.uniprot.org/uniprotkb/G3MYN5" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 2, "go_terms": [ { "name": "skeletal muscle contraction", "id": "GO:0003009", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003009", "evidence": [ { "database": "UniProtKB", "id": "G3MYN5", "url": "https://www.uniprot.org/uniprotkb/G3MYN5" } ], "pmid": "" }, { "name": "cardiac muscle contraction", "id": "GO:0060048", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0060048", "evidence": [ { "database": "UniProtKB", "id": "G3MYN5", "url": "https://www.uniprot.org/uniprotkb/G3MYN5" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [ { "pdb_id": "AF-G3MYN5-F1", "pdb_chain": "global", "start_pos": 1, "end_pos": 187, "overlap": "1.0", "method": "AlphaFold", "type": "alphafold", "resolution": -1.0, "url": "https://data.glygen.org/ln2downloads/pdb/current/AF-G3MYN5-F1.pdb", "url_external": "https://alphafold.ebi.ac.uk/entry/G3MYN5" } ], "lectin_list": [], "domain_list": [], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ], "tool_support": { "graph_view": "yes" } }, { "uniprot_canonical_ac": "G3X720-1", "uniprot_ac": "G3X720", "uniprot_id": "G3X720_BOVIN", "mass": { "chemical_mass": 23478.0, "monoisotopic_mass": 23478.0 }, "refseq": { "ac": "NP_001422324", "name": "putative uncharacterized protein C19orf81 homolog", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001422324" }, "gene_names": [ { "name": "C18H19orf81", "type": "recommended", "evidence": [ { "id": "G3X720", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3X720" } ] }, { "name": "C18H19orf81", "type": "synonym", "evidence": [ { "id": "NP_001422324", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001422324" } ] } ], "protein_names": [ { "name": "Chromosome 18 C19orf81 homolog", "type": "synonym", "evidence": [ { "id": "G3X720", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3X720/entry#names_and_taxonomy" } ] }, { "name": "putative uncharacterized protein C19orf81 homolog", "type": "synonym", "evidence": [ { "id": "NP_001422324", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001422324" } ] } ], "function": [], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Bos taurus", "taxid": 9913, "evidence": [ { "database": "UniProtKB", "id": "G3X720", "url": "https://www.uniprot.org/uniprotkb/G3X720" } ], "common_name": "Bovine", "glygen_name": "Bovine", "reference_species": "Bos taurus [9913]" } ], "gene": [ { "name": "C18H19orf81", "url": "https://www.uniprot.org/uniprotkb/G3X720", "locus": { "chromosome": "18", "start_pos": 56747299, "end_pos": 56735400, "strand": "-", "evidence": [ { "database": "Ensembl Gene", "id": "ENSBTAG00000013106", "url": "https://www.ensembl.org/id/ENSBTAG00000013106" } ] } } ], "crossref": [ { "id": "G3X720", "url": "https://alphafold.ebi.ac.uk/entry/G3X720", "database": "AlphaFoldDB", "categories": [] }, { "id": "ENSBTAG00000013106", "url": "https://bgee.org/?page=gene&gene_id=ENSBTAG00000013106", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "100140272", "url": "https://www.ncbi.nlm.nih.gov/gene/100140272", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR031746", "url": "https://www.ebi.ac.uk/interpro/entry/IPR031746", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "G3X720", "url": "https://www.orthodb.org/?gene=G3X720", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR37153", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR37153", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR37153:SF1", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR37153:SF1", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF15876", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF15876", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "NP_001422324", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001422324", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0AAA9S0V9", "url": "https://www.uniprot.org/uniprotkb/A0AAA9S0V9", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0AAA9S0V9-1", "url": "https://www.uniprot.org/uniprotkb/A0AAA9S0V9-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "G3X720", "url": "https://www.uniprot.org/uniprotkb/G3X720", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "G3X720-1", "url": "https://www.uniprot.org/uniprotkb/G3X720-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MSGGMQQEVEPLCSSAMGNPGMHRDAGALLVDRETPEEMQARSLGRSVKSSGCFPRKQYLRQVIAEYEALDRELPCIRKFPMPPAAQPLCLCMETSPEEDLTHVEVLEALEAEFPGAMESGRVSSIRFENMNVICGTAGRRDRWLIMVTDFQTRSRLLRSGLRLRGNLHPLVRHDELLLSDYRLHLRRSLVRRRMLEALGAEPTEED", "length": 207, "header": "tr|G3X720-1|G3X720_BOVIN Isoform 1 of Chromosome 18 C19orf81 homolog OS=Bos taurus OX=9913 GN=C18H19orf81 PE=4 SV=3 CANONICAL=G3X720-1" }, "isoforms": [ { "isoform_ac": "A0AAA9S0V9-1", "url": "https://www.uniprot.org/uniprotkb/A0AAA9S0V9/entry", "sequence": { "sequence": "MKGNQMPMWTQPSTFFPRGFKNKREEAAGRQSWGGWPSQSASPRPPETTLTRLPRMQQEVEPLCSSAMGNPGMHRDAGALLVDRETPEEMQARSLGRSVKSSKQYLRQVIAEYEALDRELPCIRKFPMPPAAQPLCLCMETSPEEDLTHVEVLEALEAEFPGAMESGRVSSIRFENMNVICGTAGRRDRWLIMVTDFQTRSRLLRSGLRLRGNLHPLVRHDELLLSDYRLHLRRSLVRRRMLEALGAEPTEED", "length": 253, "header": "tr|A0AAA9S0V9-1|G3X720_BOVIN Computationally mapped isoform of Chromosome 18 C19orf81 homolog OS=Bos taurus OX=9913 GN=C18H19orf81 PE=4 SV=1 CANONICAL=G3X720-1" }, "locus": { "chromosome": "18", "start_pos": 56747136, "end_pos": 56735938, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000088223.2", "url": "https://www.ensembl.org/id/ENSBTAT00000088223.2" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000075710.1", "url": "https://www.ensembl.org/id/ENSBTAP00000075710.1" } ] } }, { "isoform_ac": "G3X720-1", "url": "https://www.uniprot.org/uniprotkb/G3X720/entry", "sequence": { "sequence": "MSGGMQQEVEPLCSSAMGNPGMHRDAGALLVDRETPEEMQARSLGRSVKSSGCFPRKQYLRQVIAEYEALDRELPCIRKFPMPPAAQPLCLCMETSPEEDLTHVEVLEALEAEFPGAMESGRVSSIRFENMNVICGTAGRRDRWLIMVTDFQTRSRLLRSGLRLRGNLHPLVRHDELLLSDYRLHLRRSLVRRRMLEALGAEPTEED", "length": 207, "header": "tr|G3X720-1|G3X720_BOVIN Isoform 1 of Chromosome 18 C19orf81 homolog OS=Bos taurus OX=9913 GN=C18H19orf81 PE=4 SV=3 CANONICAL=G3X720-1" }, "locus": { "chromosome": "18", "start_pos": 56747136, "end_pos": 56735419, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000017423.6", "url": "https://www.ensembl.org/id/ENSBTAT00000017423.6" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000017423.5", "url": "https://www.ensembl.org/id/ENSBTAP00000017423.5" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [], "orthologs": [], "go_annotation": {}, "pro_annotation": [], "site_annotation": [], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [ { "pdb_id": "AF-G3X720-F1", "pdb_chain": "global", "start_pos": 1, "end_pos": 207, "overlap": "1.0", "method": "AlphaFold", "type": "alphafold", "resolution": -1.0, "url": "https://data.glygen.org/ln2downloads/pdb/current/AF-G3X720-F1.pdb", "url_external": "https://alphafold.ebi.ac.uk/entry/G3X720" } ], "lectin_list": [], "domain_list": [], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ], "tool_support": { "graph_view": "yes" } }, { "uniprot_canonical_ac": "G3N3X2-1", "uniprot_ac": "G3N3X2", "uniprot_id": "G3N3X2_BOVIN", "mass": { "chemical_mass": 113023.0, "monoisotopic_mass": 113023.0 }, "refseq": {}, "gene_names": [ { "name": "SRBD1", "type": "recommended", "evidence": [ { "id": "G3N3X2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3N3X2" } ] } ], "protein_names": [ { "name": "S1 RNA-binding domain-containing protein 1", "type": "recommended", "evidence": [ { "id": "G3N3X2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3N3X2/entry#names_and_taxonomy" } ] } ], "function": [ { "annotation": "DNA- and histone-binding protein that localizes to the central axes of mitotic chromosomes. Promotes chromosome segregation by facilitating TOP2A recruitment to mitotic chromosomes, thereby preventing anaphase failure. During prophase, safeguards the decatenation process to avoid the formation of difficult-to-resolve DNA structures, preventing chromosome missegregation. Also contributes to the regulation of nucleus pulposus cell senescence.", "evidence": [ { "database": "UniProtKB", "id": "A0AAA9S1R5", "url": "https://www.uniprot.org/uniprotkb/A0AAA9S1R5#function" }, { "database": "UniProtKB", "id": "ARBA00094394", "url": "https://www.uniprot.org/uniprotkb/ARBA00094394#function" }, { "database": "UniProtKB", "id": "A0AAA9TWS6", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TWS6#function" }, { "database": "UniProtKB", "id": "G3N3X2", "url": "https://www.uniprot.org/uniprotkb/G3N3X2#function" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Bos taurus", "taxid": 9913, "evidence": [ { "database": "UniProtKB", "id": "G3N3X2", "url": "https://www.uniprot.org/uniprotkb/G3N3X2" } ], "common_name": "Bovine", "glygen_name": "Bovine", "reference_species": "Bos taurus [9913]" } ], "gene": [ { "name": "SRBD1", "url": "https://www.uniprot.org/uniprotkb/G3N3X2", "locus": { "chromosome": "11", "start_pos": 27806038, "end_pos": 28050758, "strand": "+", "evidence": [ { "database": "Ensembl Gene", "id": "ENSBTAG00000007508", "url": "https://www.ensembl.org/id/ENSBTAG00000007508" } ] } } ], "crossref": [ { "id": "G3N3X2", "url": "https://alphafold.ebi.ac.uk/entry/G3N3X2", "database": "AlphaFoldDB", "categories": [] }, { "id": "ENSBTAG00000007508", "url": "https://bgee.org/?page=gene&gene_id=ENSBTAG00000007508", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "cd05685", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd05685", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "513877", "url": "https://www.ncbi.nlm.nih.gov/gene/513877", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR003029", "url": "https://www.ebi.ac.uk/interpro/entry/IPR003029", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR006641", "url": "https://www.ebi.ac.uk/interpro/entry/IPR006641", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR010994", "url": "https://www.ebi.ac.uk/interpro/entry/IPR010994", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR012337", "url": "https://www.ebi.ac.uk/interpro/entry/IPR012337", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR012340", "url": "https://www.ebi.ac.uk/interpro/entry/IPR012340", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR018974", "url": "https://www.ebi.ac.uk/interpro/entry/IPR018974", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR023319", "url": "https://www.ebi.ac.uk/interpro/entry/IPR023319", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR023323", "url": "https://www.ebi.ac.uk/interpro/entry/IPR023323", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR032639", "url": "https://www.ebi.ac.uk/interpro/entry/IPR032639", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR037027", "url": "https://www.ebi.ac.uk/interpro/entry/IPR037027", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR041692", "url": "https://www.ebi.ac.uk/interpro/entry/IPR041692", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR044146", "url": "https://www.ebi.ac.uk/interpro/entry/IPR044146", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR050437", "url": "https://www.ebi.ac.uk/interpro/entry/IPR050437", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR055179", "url": "https://www.ebi.ac.uk/interpro/entry/IPR055179", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR060575", "url": "https://www.ebi.ac.uk/interpro/entry/IPR060575", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "E1BIF3", "url": "https://www.orthodb.org/?gene=E1BIF3", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "G3N3X2", "url": "https://www.orthodb.org/?gene=G3N3X2", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR10724", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR10724", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR10724:SF10", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR10724:SF10", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00575", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00575", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF09371", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF09371", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF12836", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF12836", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF16921", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF16921", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF17674", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF17674", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF22706", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF22706", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "A0AAA9S1R5", "url": "https://www.uniprot.org/uniprotkb/A0AAA9S1R5", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0AAA9S1R5-1", "url": "https://www.uniprot.org/uniprotkb/A0AAA9S1R5-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0AAA9TWS6", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TWS6", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0AAA9TWS6-1", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TWS6-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "E1BIF3", "url": "https://www.uniprot.org/uniprotkb/E1BIF3", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "E1BIF3-1", "url": "https://www.uniprot.org/uniprotkb/E1BIF3-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "G3N3X2", "url": "https://www.uniprot.org/uniprotkb/G3N3X2", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "G3N3X2-1", "url": "https://www.uniprot.org/uniprotkb/G3N3X2-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MLSSTQTHGASDTPGGKMSSLPRRAKAKVQTVIPKDEFSSFSELSSASEDDKEDSAWEPQKKVPRSRKPPVSKVSKPKRVPRVKNTLQISDGSEDVAVKEELNNSIAIADVDLEDKNKLETGQTLKTAKTKRKNSAQSPSARRTKKLKTDEEANKASSLESRNNSTEIPSTSAMWEGGCKEEENKDYFTCGQPPLKKVKTETCPQGQPVRLPENISNIEEVEMNWDIVQVLSERTDIELWVCANIIRLFNDDNTIPFIIRYRRELINNLDADSLREVQQTLEELRAVAKKAHSTIQKIKKEGKMSECLLKALLNCKTFEELEHVSAPYKTGSKGTKAQRAKQLGLEGAARTLLENPGELSLLSYIKPNVKGLSALQDIETGVQHILADMIAKDKDTLDFIRKLCQDRYIHIQSSLAKVSSKKVNEKDIDKFQLYQNFSCNIRNIQHHQILAINRGENLKILTVKVNIPDGVKKEFCKWCIQNRWRPRGFARPELMKILYNSLDDSFKRLIYPLLCREFRAKLTSDAEKESVMMFGRNLRQLLLTSPVPGRTLMGVDPGYKHGCKLAVISPTSQILHTDVVYLHCGQGFREAEKIKRLLLNFNCSTVVIGNGTACRETEAYFADLIMNNYFAPLDVVYCIVSEAGASIYSVSPEANKEMPELDPNLRSAVSIARRVQDPLAELVKIEPKHIGVGMYQHDVSQTLLKATLDSVVEECVSFVGVDINICSEVLLRHIAGLNANRAKNIIEWREKNGPFINREQLKKVKGLGPKSFQQCAGFIRVNQDYIRTFCSQQTESAGQTQGVAVTASAGVEVTNEKQGKKRSKTTVNVVLKPNPLDQTCIHPESYDTAMRFLSFIGGTLYEIGKPEMQQKINSFLEKEGMEKTAERLQTTVHTLQVIVDGLSQPESFDFRTDFDKPDFKRSIVCLEDLQVGTVLTGKVENATLFGIFVDIGVGRSGLIPIRNVTEAKLSKTKKRRSLGLGPGERVEVRVLNIDIPRSRITLDLIRVL", "length": 1008, "header": "tr|G3N3X2-1|G3N3X2_BOVIN Isoform 1 of S1 RNA-binding domain-containing protein 1 OS=Bos taurus OX=9913 GN=SRBD1 PE=4 SV=3 CANONICAL=G3N3X2-1" }, "isoforms": [ { "isoform_ac": "A0AAA9S1R5-1", "url": "https://www.uniprot.org/uniprotkb/A0AAA9S1R5/entry", "sequence": { "sequence": "MLSSTQTHGASDTPGGKMSSLPRRAKAKVQTVIPKDEFSSFSELSSASEDDKEDSAWEPQKKVPRSRKPPVSKVSKPKRVPRVKNTLQISDGSEDVAVKEELNNSIAIADVDLEDKNKLETGQTLKTAKTKRKNSAQSPSARRTKKLKTDEEANKASSLESRNNSTEIPSTSAMWEGGCKEEENKDYFTCGQPPLKKVKTETCPQGQPVRLPENISNIEEVEMNWDIVQVLSERTDIELWVCANIIRLFNDDNTIPFIIRYRRELINNLDADSLREVQQTLEELRAVAKKAHSTIQKIKKEGKMSECLLKALLNCKTFEELEHVSAPYKTGSKGTKAQRAKQLGLEGAARTLLENPGELSLLSYIKPNVKGLSALQDIETGVQHILADMIAKDKDTLDFIRKLCQDRYIHIQSSLAKVSSKKVNEKDIDKFQLYQNFSCNIRNIQHHQILAINRGENLKILTVKVNIPDGVKKEFCKWCIQNRWRPRGFARPELMKILYNSLDDSFKRLIYPLLCREFRAKLTSDAEKESVMMFGRNLRQLLLTSPVPGRTLMGVDPGYKHGCKLAVISPTSQILHTDVVYLHCGQGFREAEKIKRLLLNFNCSTVVIGNGTACRETEAYFADLIMNNYFAPLDVVYCIVSEAGASIYSVSPEANKEMPELDPNLRSAVSIARRVQDPLAELVKIEPKHIGVGMYQHDVSQTLLKATLDSVVEECVSFVGVDINICSEVLLRHIAGLNANRAKNIIEWREKNGPFINREQLKKVKGLGPKSFQQCAGFIRVNQDYIRTFCRFLSFIGGTLYEIGKPEMQQKINSFLEKEGMEKTAERLQTTVHTLQVIVDGLSQPESFDFRTDFDKPDFKRSIVCLEDLQVGTVLTGKVENATLFGIFVDIGVGRSGLIPIRNVTEAKLSKTKKRRSLGLGPGERVEVRVLNIDIPRSRITLDLIRVL", "length": 948, "header": "tr|A0AAA9S1R5-1|G3N3X2_BOVIN Computationally mapped isoform of S1 RNA-binding domain-containing protein 1 OS=Bos taurus OX=9913 GN=SRBD1 PE=4 SV=2 CANONICAL=G3N3X2-1" }, "locus": { "chromosome": "11", "start_pos": 28050570, "end_pos": 27806640, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000110445.2", "url": "https://www.ensembl.org/id/ENSBTAT00000110445.2" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000077249.2", "url": "https://www.ensembl.org/id/ENSBTAP00000077249.2" } ] } }, { "isoform_ac": "A0AAA9TWS6-1", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TWS6/entry", "sequence": { "sequence": "MWVQCLHWEDPVEKEIATHSSIFAWEIPWTEEPGRLQSTGSQRVGYDLATKQQHLENTGSQIYCETTTAHQYALACSRSSLCEYLCFTYISVQSINTKKNNSIAIADVDLEDKNKLETGQTLKTAKTKRKNSAQSPSARRTKKLKTDEEANKASSLESRNNSTEIPSTSAMWEGGCKEEENKDYFTCGQPPLKKVKTETCPQGQPVRLPENISNIEEVEMNWDIVQVLSERTDIELWVCANIIRLFNDDNTIPFIIRYRRELINNLDADSLREVQQTLEELRAVAKKAHSTIQKIKKEGKMSECLLKALLNCKTFEELEHVSAPYKTGSKGTKAQRAKQLGLEGAARTLLENPGELSLLSYIKPNVKGLSALQDIETGVQHILADMIAKDKDTLDFIRKLCQDRYIHIQSSLAKVSSKKVNEKDIDKFQLYQNFSCNIRNIQHHQILAINRGENLKILTVKVNIPDGVKKEFCKWCIQNRWRPRGFARPELMKILYNSLDDSFKRLIYPLLCREFRAKLTSDAEKESVMMFGRNLRQLLLTSPVPGRTLMGVDPGYKHGCKLAVISPTSQILHTDVVYLHCGQGFREAEKIKRLLLNFNCSTVVIGNGTACRETEAYFADLIMNNYFAPLDVVYCIVSEAGASIYSVSPEANKEMPELDPNLRSAVSIARRVQDPLAELVKIEPKHIGVGMYQHDVSQTLLKATLDSVVEECVSFVGVDINICSEVLLRHIAGLNANRAKNIIEWREKNGPFINREQLKKVKGLGPKSFQQCAGFIRVNQDYIRTFCSSQQTESAGQTQGVAVTASAGVEVTNEKQGKKRSKTTVNVVLKPNPLDQTCIHPESYDTAMRFLSFIGGTLYEIGKPEMQQKINSFLEKEGMEKTAERLQTTVHTLQVIVDGLSQPESFDFRTDFDKPDFKRSIVCLEDLQVGTVLTGKVENATLFGIFVDIGVGRSGLIPIRNVTEAKLSKTKKRRSLGLGPGERVEVRVLNIDIPRSRITLDLIRVL", "length": 1006, "header": "tr|A0AAA9TWS6-1|A0AAA9TWS6_BOVIN Computationally mapped isoform of S1 RNA-binding domain-containing protein 1 OS=Bos taurus OX=9913 GN=SRBD1 PE=4 SV=1 CANONICAL=G3N3X2-1" }, "locus": { "chromosome": "11", "start_pos": 28038131, "end_pos": 27806640, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000128522.1", "url": "https://www.ensembl.org/id/ENSBTAT00000128522.1" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000102810.1", "url": "https://www.ensembl.org/id/ENSBTAP00000102810.1" } ] } }, { "isoform_ac": "E1BIF3-1", "url": "https://www.uniprot.org/uniprotkb/E1BIF3/entry", "sequence": { "sequence": "MLSSTQTHGASDTPGGKMSSLPRRAKAKVQTVIPKDEFSSFSELSSASEDDKEDSAWEPQKKVPRSRKPPVSKVSKPKRVPRVKNTLQISDGSEDVAVKEELNNSIAIADVDLEDKNKLETGQTLKTAKTKRKNSAQSPSARRTKKLKTDEEANKASSLESRNNSTEIPSTSAMWEGGCKEEENKDYFTCGQPPLKKVKTETCPQGQPVRLPENISNIEEVEMNWDIVQVLSERTDIELWVCANIIRLFNDDNTIPFIIRYRRELINNLDADSLREVQQTLEELRAVAKKAHSTIQKIKKEGKMSECLLKALLNCKTFEELEHVSAPYKTGSKGTKAQRAKQLGLEGAARTLLENPGELSLLSYIKPNVKGLSALQDIETGVQHILADMIAKDKDTLDFIRKLCQDRYIHIQSSLAKVSSKKVNEKDIDKFQLYQNFSCNIRNIQHHQILAINRGENLKILTVKVNIPDGVKKEFCKWCIQNRAKLTSDAEKESVMMFGRNLRQLLLTSPVPGRTLMGVDPGYKHGCKLAVISPTSQILHTDVVYLHCGQGFREAEKIKRLLLNFNCSTVVIGNGTACRETEAYFADLIMNNYFAPLDVVYCIVSEAGASIYSVSPEANKEMPELDPNLRSAVSIARRVQDPLAELVKIEPKHIGVGMYQHDVSQTLLKATLDSVVEECVSFVGVDINICSEVLLRHIAGLNANRAKNIIEWREKNGPFINREQLKKVKGLGPKSFQQCAGFIRVNQDYIRTFCSSQQTESAGQTQGVAVTASAGVEVTNEKQGKKRSKTTVNVVLKPNPLDQTCIHPESYDTAMRFLSFIGGTLYEIGKPEMQQKINSFLEKEGMEKTAERLQTTVHTLQVIVDGLSQPESFDFRTDFDKPDFKRSIVCLEDLQVGTVLTGKVENATLFGIFVDIGVGRSGLIPIRNVTEAKLSKTKKRRSLGLGPGERVEVRVLNIDIPRSRITLDLIRVL", "length": 973, "header": "tr|E1BIF3-1|E1BIF3_BOVIN Computationally mapped isoform of S1 RNA binding domain 1 OS=Bos taurus OX=9913 GN=SRBD1 PE=4 SV=3 CANONICAL=G3N3X2-1" }, "locus": { "chromosome": "11", "start_pos": 28050570, "end_pos": 27806640, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000009881.7", "url": "https://www.ensembl.org/id/ENSBTAT00000009881.7" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000009881.7", "url": "https://www.ensembl.org/id/ENSBTAP00000009881.7" } ] } }, { "isoform_ac": "G3N3X2-1", "url": "https://www.uniprot.org/uniprotkb/G3N3X2/entry", "sequence": { "sequence": "MLSSTQTHGASDTPGGKMSSLPRRAKAKVQTVIPKDEFSSFSELSSASEDDKEDSAWEPQKKVPRSRKPPVSKVSKPKRVPRVKNTLQISDGSEDVAVKEELNNSIAIADVDLEDKNKLETGQTLKTAKTKRKNSAQSPSARRTKKLKTDEEANKASSLESRNNSTEIPSTSAMWEGGCKEEENKDYFTCGQPPLKKVKTETCPQGQPVRLPENISNIEEVEMNWDIVQVLSERTDIELWVCANIIRLFNDDNTIPFIIRYRRELINNLDADSLREVQQTLEELRAVAKKAHSTIQKIKKEGKMSECLLKALLNCKTFEELEHVSAPYKTGSKGTKAQRAKQLGLEGAARTLLENPGELSLLSYIKPNVKGLSALQDIETGVQHILADMIAKDKDTLDFIRKLCQDRYIHIQSSLAKVSSKKVNEKDIDKFQLYQNFSCNIRNIQHHQILAINRGENLKILTVKVNIPDGVKKEFCKWCIQNRWRPRGFARPELMKILYNSLDDSFKRLIYPLLCREFRAKLTSDAEKESVMMFGRNLRQLLLTSPVPGRTLMGVDPGYKHGCKLAVISPTSQILHTDVVYLHCGQGFREAEKIKRLLLNFNCSTVVIGNGTACRETEAYFADLIMNNYFAPLDVVYCIVSEAGASIYSVSPEANKEMPELDPNLRSAVSIARRVQDPLAELVKIEPKHIGVGMYQHDVSQTLLKATLDSVVEECVSFVGVDINICSEVLLRHIAGLNANRAKNIIEWREKNGPFINREQLKKVKGLGPKSFQQCAGFIRVNQDYIRTFCSQQTESAGQTQGVAVTASAGVEVTNEKQGKKRSKTTVNVVLKPNPLDQTCIHPESYDTAMRFLSFIGGTLYEIGKPEMQQKINSFLEKEGMEKTAERLQTTVHTLQVIVDGLSQPESFDFRTDFDKPDFKRSIVCLEDLQVGTVLTGKVENATLFGIFVDIGVGRSGLIPIRNVTEAKLSKTKKRRSLGLGPGERVEVRVLNIDIPRSRITLDLIRVL", "length": 1008, "header": "tr|G3N3X2-1|G3N3X2_BOVIN Isoform 1 of S1 RNA-binding domain-containing protein 1 OS=Bos taurus OX=9913 GN=SRBD1 PE=4 SV=3 CANONICAL=G3N3X2-1" }, "locus": { "chromosome": "11", "start_pos": 28050570, "end_pos": 27806640, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000066115.3", "url": "https://www.ensembl.org/id/ENSBTAT00000066115.3" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000056635.3", "url": "https://www.ensembl.org/id/ENSBTAP00000056635.3" } ] } } ], "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "other", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 806, "start_aa": "Thr", "end_pos": 806, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr806", "evidence": [ { "id": "", "database": "GlyGen", "url": "https://data.glygen.org/" } ], "filter_code": "000000000000000010000.00000000001000.0.01000" } ], "phosphorylation": [], "glycation": [], "keywords": [ "glycoprotein", "glycoprotein_predicted" ], "publication": [], "pathway": [], "orthologs": [], "go_annotation": { "categories": [ { "name": "Molecular Function", "total": 4, "go_terms": [ { "name": "nucleic acid binding", "id": "GO:0003676", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003676", "evidence": [ { "database": "UniProtKB", "id": "G3N3X2", "url": "https://www.uniprot.org/uniprotkb/G3N3X2" } ], "pmid": "" }, { "name": "RNA binding", "id": "GO:0003723", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003723", "evidence": [ { "database": "UniProtKB", "id": "G3N3X2", "url": "https://www.uniprot.org/uniprotkb/G3N3X2" } ], "pmid": "" }, { "name": "mRNA binding", "id": "GO:0003729", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003729", "evidence": [ { "database": "UniProtKB", "id": "G3N3X2", "url": "https://www.uniprot.org/uniprotkb/G3N3X2" } ], "pmid": "" }, { "name": "structural constituent of ribosome", "id": "GO:0003735", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003735", "evidence": [ { "database": "UniProtKB", "id": "G3N3X2", "url": "https://www.uniprot.org/uniprotkb/G3N3X2" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 2, "go_terms": [ { "name": "nucleobase-containing compound metabolic process", "id": "GO:0006139", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006139", "evidence": [ { "database": "UniProtKB", "id": "G3N3X2", "url": "https://www.uniprot.org/uniprotkb/G3N3X2" } ], "pmid": "" }, { "name": "translation", "id": "GO:0006412", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006412", "evidence": [ { "database": "UniProtKB", "id": "G3N3X2", "url": "https://www.uniprot.org/uniprotkb/G3N3X2" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 103, "end_pos": 105, "annotation": "n_glycosylation_sequon" }, { "start_pos": 163, "end_pos": 165, "annotation": "n_glycosylation_sequon" }, { "start_pos": 164, "end_pos": 166, "annotation": "n_glycosylation_sequon" }, { "start_pos": 214, "end_pos": 216, "annotation": "n_glycosylation_sequon" }, { "start_pos": 436, "end_pos": 438, "annotation": "n_glycosylation_sequon" }, { "start_pos": 602, "end_pos": 604, "annotation": "n_glycosylation_sequon" }, { "start_pos": 610, "end_pos": 612, "annotation": "n_glycosylation_sequon" }, { "start_pos": 941, "end_pos": 943, "annotation": "n_glycosylation_sequon" }, { "start_pos": 963, "end_pos": 965, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [ { "pdb_id": "AF-G3N3X2-F1", "pdb_chain": "global", "start_pos": 1, "end_pos": 1008, "overlap": "1.0", "method": "AlphaFold", "type": "alphafold", "resolution": -1.0, "url": "https://data.glygen.org/ln2downloads/pdb/current/AF-G3N3X2-F1.pdb", "url_external": "https://alphafold.ebi.ac.uk/entry/G3N3X2" } ], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "G3N3X2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3N3X2" }, { "id": "PS50126", "database": "PROSITE", "url": "https://prosite.expasy.org/PS50126" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "S1 motif", "eco_id": "ECO_0000259", "start_pos": 932, "end_pos": 1005, "start_aa": "Gly", "end_aa": "Ile", "glycosite_overlap": [] } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [ 806 ], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 103, "end_pos": 105 }, { "start_pos": 163, "end_pos": 165 }, { "start_pos": 164, "end_pos": 166 }, { "start_pos": 214, "end_pos": 216 }, { "start_pos": 436, "end_pos": 438 }, { "start_pos": 602, "end_pos": 604 }, { "start_pos": 610, "end_pos": 612 }, { "start_pos": 941, "end_pos": 943 }, { "start_pos": 963, "end_pos": 965 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 1 }, { "field": "total_sites", "count": 1 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 1 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "exact_sites", "count": 1 }, { "field": "exact_o_linked_sites", "count": 1 }, { "field": "fuzzy_sites", "count": 0 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_pos", "start_aa", "end_pos", "end_aa", "residue", "site_lbl" ] }, { "table_id": 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"total", "count": 1 }, { "field": "total_sites", "count": 1 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 1 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "exact_sites", "count": 1 }, { "field": "exact_o_linked_sites", "count": 1 }, { "field": "fuzzy_sites", "count": 0 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_pos", "start_aa", "end_pos", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ], "tool_support": { "graph_view": "yes" } }, { "uniprot_canonical_ac": "G5E5E4-1", "uniprot_ac": "G5E5E4", "uniprot_id": "G5E5E4_BOVIN", "mass": { "chemical_mass": 73579.0, "monoisotopic_mass": 73579.0 }, "refseq": {}, "gene_names": [ { "name": "HDAC10", "type": "recommended", "evidence": [ { "id": "G5E5E4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G5E5E4" } ] } ], "protein_names": [ { "name": "Histone deacetylase 10", "type": "synonym", "evidence": [ { "id": "G5E5E4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G5E5E4/entry#names_and_taxonomy" } ] } ], "function": [], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Bos taurus", "taxid": 9913, "evidence": [ { "database": "UniProtKB", "id": "G5E5E4", "url": "https://www.uniprot.org/uniprotkb/G5E5E4" } ], "common_name": "Bovine", "glygen_name": "Bovine", "reference_species": "Bos taurus [9913]" } ], "gene": [ { "name": "HDAC10", "url": "https://www.uniprot.org/uniprotkb/G5E5E4", "locus": { "chromosome": "5", "start_pos": 119611256, "end_pos": 119616810, "strand": "+", "evidence": [ { "database": "Ensembl Gene", "id": "ENSBTAG00000011000", "url": "https://www.ensembl.org/id/ENSBTAG00000011000" } ] } } ], "crossref": [ { "id": "G5E5E4", "url": "https://alphafold.ebi.ac.uk/entry/G5E5E4", "database": "AlphaFoldDB", "categories": [] }, { "id": "ENSBTAG00000011000", "url": "https://bgee.org/?page=gene&gene_id=ENSBTAG00000011000", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "IPR000286", "url": "https://www.ebi.ac.uk/interpro/entry/IPR000286", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR023696", "url": "https://www.ebi.ac.uk/interpro/entry/IPR023696", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR023801", "url": "https://www.ebi.ac.uk/interpro/entry/IPR023801", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR037138", "url": "https://www.ebi.ac.uk/interpro/entry/IPR037138", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "G3X7P5", "url": "https://www.orthodb.org/?gene=G3X7P5", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR10625", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR10625", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR10625:SF43", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR10625:SF43", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00850", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00850", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "A0AAA9S2S5", "url": "https://www.uniprot.org/uniprotkb/A0AAA9S2S5", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0AAA9S2S5-1", "url": "https://www.uniprot.org/uniprotkb/A0AAA9S2S5-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0AAA9TCH6", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TCH6", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0AAA9TCH6-1", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TCH6-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "G3X7P5", "url": "https://www.uniprot.org/uniprotkb/G3X7P5", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "G3X7P5-1", "url": "https://www.uniprot.org/uniprotkb/G3X7P5-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "G5E5E4", "url": "https://www.uniprot.org/uniprotkb/G5E5E4", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "G5E5E4-1", "url": "https://www.uniprot.org/uniprotkb/G5E5E4-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MGTALVYHEDMTATRLLWDDPECEIECPERLTTALERLQQHGLKQRCLQLVAREASEAELGLVHSPEYVALLQGTQALGTRELQALSKEYDAVYLHPSTFHCARLAVGAALQLVDAVLTGAVRNGLALVRPPGHHSQRATANGFCVFNNVAIAAKHAQQKHGLRRILIVDWDVHHGQGIQYIFEDDPSVLYFSWHRYEHGHFWPCLRESDADAVGRGRGLGFTVNLPWNQVGMGNADYVAAFLHVLLPLAFEFDPELVLVSAGFDSAIGDPEGQMLATPECFAHLTHLLQVLAGGRVCAVLEGGYHLESLSQSVCMMVRALLGDPALPLSGPMEPHGSALESLQCVRAAQAPHWVSLQQQGAAPVLSPGTPCPEGRPSPLPLGEPQFKAVVTQAAAALSSLLDQLRLHPTPPVRVAVALIAPDTGLALPPGVLCEEGSLPQEETQAWARPHEALAQDGALTALGKVLYLLDRILDGQVSSGMAATPVPAAAATLDVAVRYGLSHGAQRLLCVAVGQLDRPPGLTDDGRNLWLNIGGEEAAAPSMFHVSVPLPVTTGGFLSCALALVLPLAYSFQPDLVLVALGPAHGLRDPQAALLAALLRGPAGGRVFALVDEESTPQLATVLARVLNGEAPPSLGPFSMAAPEDTQALMYLRGRLEPRWKMLQLEVGQGGSIYTVEETLRISPPGACC", "length": 690, "header": "tr|G5E5E4-1|G5E5E4_BOVIN Isoform 1 of Histone deacetylase 10 OS=Bos taurus OX=9913 GN=HDAC10 PE=3 SV=1 CANONICAL=G5E5E4-1" }, "isoforms": [ { "isoform_ac": "A0AAA9S2S5-1", "url": "https://www.uniprot.org/uniprotkb/A0AAA9S2S5/entry", "sequence": { "sequence": "MGTALVYHEDMTATRLLWDDPECEIECPERLTTALERLQQHGLKQRCLQLVAREASEAELGLVHSPEYVALLQGTQALGTRELQALSKEYDAVYLHPSTFHCARLAVGAALQLVDAVLTGAVRNGLALVRPPGHHSQRATANGFCVFNNVAIAAKHAQQKHGLRRILIVDWDVHHGQGIQYIFEDDPSVLYFSWHRYEHGHFWPCLRESDADAVGRGRGLGFTVNLPWNQVGMGNADYVAAFLHVLLPLAFEGGYHLESLSQSVCMMVRALLGDPALPLSGPMEPHGSALESLQCVRAAQAPHWVSLQQQGAAPVLSPGTPCPEGRPSPLPLGEPQFKAVVTQAAAALSSLLDQLRLHPTPPVRVAVALIAPDTGLALPPGVLCEEGSLPQEETQAWARPHEALAQDGALTALGKVLYLLDRILDGQVSSGMAATPVPAAAATLDVAVRYGLSHGAQRLLCVAVGQLDRPPGLTDDGRNLWLNIGGEEAAAPSMFHVSVPLPVTTGGFLSCALALVLPLAYSFQPDLVLVALGPAHGLRDPQAALLAALLRGPAGGRVFALVDEESTPQLATVLARVLNGEAPPSLGPFSMAAPEDTQALMYLRGRLEPRWKMLQCCDLAA", "length": 621, "header": "tr|A0AAA9S2S5-1|G5E5E4_BOVIN Computationally mapped isoform of Histone deacetylase 10 OS=Bos taurus OX=9913 GN=HDAC10 PE=3 SV=1 CANONICAL=G5E5E4-1" }, "locus": { "chromosome": "5", "start_pos": 119616568, "end_pos": 119611657, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000111164.1", "url": "https://www.ensembl.org/id/ENSBTAT00000111164.1" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000079362.1", "url": "https://www.ensembl.org/id/ENSBTAP00000079362.1" } ] } }, { "isoform_ac": "A0AAA9TCH6-1", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TCH6/entry", "sequence": { "sequence": "MGTALVYHEDMTATRLLWDDPECEIECPERLTTALERLQQHGLKQRCLQLVAREASEAELGLVHSPEYVALLQGTQALGTRELQALSKEYDAVYLHPSTFHCARLAVGAALQLVDAVLTGAVRNGLALVRPPGHHSQRATANGFCVFNNVAIAAKHAQQKHGLRRILIVDWDVHHGQGIQYIFEDDPSVLYFSWHRYEHGHFWPCLRESDADAVGRGRGLGFTVNLPWNQVGMGNADYVAAFLHVLLPLAFEGQMLATPECFAHLTHLLQVLAGGRVCAVLEGGYHLESLSQSVCMMVRALLGDPALPLSGPMEPHGSALESLQCVRAAQAPHWVSLQQQGAAPVLSPGTPCPEGRPSPLPLGEPQFKAVVTQAAAALSSLLDQLRLHPTPPVRVAVALIAPDTGLALPPGVLCEEGSLPQEETQAWARPHEALAQDGALTALGKVLYLLDRILDGQVSSGMAATPVPAAAATLDVAVRYGLSHGAQRLLCVAVGQLDRPPGLTDDGRNLWLNIGGEEAAAPSMFHVSVPLPVTTGGFLSCALALVLPLAYSFQPDLVLVALGPAHGLRDPQAALLAALLRGPAGGRVFALVDEESTPQLATVLARVLNGEAPPSLGPFSMAAPEDTQALMYLRGRLEPRWKMLQCCDLAA", "length": 651, "header": "tr|A0AAA9TCH6-1|G5E5E4_BOVIN Computationally mapped isoform of Histone deacetylase 10 OS=Bos taurus OX=9913 GN=HDAC10 PE=3 SV=1 CANONICAL=G5E5E4-1" }, "locus": { "chromosome": "5", "start_pos": 119616568, "end_pos": 119611657, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000101494.1", "url": "https://www.ensembl.org/id/ENSBTAT00000101494.1" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000094562.1", "url": "https://www.ensembl.org/id/ENSBTAP00000094562.1" } ] } }, { "isoform_ac": "G3X7P5-1", "url": "https://www.uniprot.org/uniprotkb/G3X7P5/entry", "sequence": { "sequence": "MGTALVYHEDMTATRLLWDDPECEIECPERLTTALERLQQHGLKQRCLQLVAREASEAELGLVHSPEYVALLQGTQALGTRELQALSKDSCAPLLSASLSAVTWQLEVGQGGSIYTVEETLRISPPGACC", "length": 130, "header": "tr|G3X7P5-1|G3X7P5_BOVIN Computationally mapped isoform of Histone deacetylase 10 OS=Bos taurus OX=9913 GN=HDAC10 PE=4 SV=2 CANONICAL=G5E5E4-1" }, "locus": { "chromosome": "5", "start_pos": 119616568, "end_pos": 119611584, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000042583.4", "url": "https://www.ensembl.org/id/ENSBTAT00000042583.4" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000040218.4", "url": "https://www.ensembl.org/id/ENSBTAP00000040218.4" } ] } }, { "isoform_ac": "G5E5E4-1", "url": "https://www.uniprot.org/uniprotkb/G5E5E4/entry", "sequence": { "sequence": "MGTALVYHEDMTATRLLWDDPECEIECPERLTTALERLQQHGLKQRCLQLVAREASEAELGLVHSPEYVALLQGTQALGTRELQALSKEYDAVYLHPSTFHCARLAVGAALQLVDAVLTGAVRNGLALVRPPGHHSQRATANGFCVFNNVAIAAKHAQQKHGLRRILIVDWDVHHGQGIQYIFEDDPSVLYFSWHRYEHGHFWPCLRESDADAVGRGRGLGFTVNLPWNQVGMGNADYVAAFLHVLLPLAFEFDPELVLVSAGFDSAIGDPEGQMLATPECFAHLTHLLQVLAGGRVCAVLEGGYHLESLSQSVCMMVRALLGDPALPLSGPMEPHGSALESLQCVRAAQAPHWVSLQQQGAAPVLSPGTPCPEGRPSPLPLGEPQFKAVVTQAAAALSSLLDQLRLHPTPPVRVAVALIAPDTGLALPPGVLCEEGSLPQEETQAWARPHEALAQDGALTALGKVLYLLDRILDGQVSSGMAATPVPAAAATLDVAVRYGLSHGAQRLLCVAVGQLDRPPGLTDDGRNLWLNIGGEEAAAPSMFHVSVPLPVTTGGFLSCALALVLPLAYSFQPDLVLVALGPAHGLRDPQAALLAALLRGPAGGRVFALVDEESTPQLATVLARVLNGEAPPSLGPFSMAAPEDTQALMYLRGRLEPRWKMLQLEVGQGGSIYTVEETLRISPPGACC", "length": 690, "header": "tr|G5E5E4-1|G5E5E4_BOVIN Isoform 1 of Histone deacetylase 10 OS=Bos taurus OX=9913 GN=HDAC10 PE=3 SV=1 CANONICAL=G5E5E4-1" }, "locus": { "chromosome": "5", "start_pos": 119616568, "end_pos": 119611584, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000014602.6", "url": "https://www.ensembl.org/id/ENSBTAT00000014602.6" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000014602.5", "url": "https://www.ensembl.org/id/ENSBTAP00000014602.5" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [], "orthologs": [], "go_annotation": { "categories": [ { "name": "Biological Process", "total": 5, "go_terms": [ { "name": "positive regulation of mismatch repair", "id": "GO:0032425", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0032425", "evidence": [ { "database": "UniProtKB", "id": "G5E5E4", "url": "https://www.uniprot.org/uniprotkb/G5E5E4" } ], "pmid": "" }, { "name": "negative regulation of transcription by RNA polymerase II", "id": "GO:0000122", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000122", "evidence": [ { "database": "UniProtKB", "id": "G5E5E4", "url": "https://www.uniprot.org/uniprotkb/G5E5E4" } ], "pmid": "" }, { "name": "macroautophagy", "id": 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{ "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ], "tool_support": { "graph_view": "yes" } }, { "uniprot_canonical_ac": "F6RN21-1", "uniprot_ac": "F6RN21", "uniprot_id": "F6RN21_BOVIN", "mass": { "chemical_mass": 72473.0, "monoisotopic_mass": 72473.0 }, "refseq": {}, "gene_names": [ { "name": "PABPC4", "type": "recommended", "evidence": [ { "id": "F6RN21", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F6RN21" } ] } ], "protein_names": [ { "name": "Polyadenylate-binding protein", "type": "recommended", "evidence": [ { "id": "F6RN21", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F6RN21/entry#names_and_taxonomy" } ] }, { "name": "PABP", "type": "synonym", "evidence": [ { "id": "F6RN21", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F6RN21/entry#names_and_taxonomy" } ] } ], "function": [ { "annotation": "Binds the poly(A) tail of mRNA.", "evidence": [ { "database": "UniProtKB", "id": "F6RN21", "url": "https://www.uniprot.org/uniprotkb/F6RN21#function" }, { "database": "UniProtKB", "id": "RU362004", "url": "https://www.uniprot.org/uniprotkb/RU362004#function" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Bos taurus", "taxid": 9913, "evidence": [ { "database": "UniProtKB", "id": "F6RN21", "url": "https://www.uniprot.org/uniprotkb/F6RN21" } ], "common_name": "Bovine", "glygen_name": "Bovine", "reference_species": "Bos taurus [9913]" } ], "gene": [ { "name": "PABPC4", "url": "https://www.uniprot.org/uniprotkb/F6RN21", "locus": { "chromosome": "3", "start_pos": 106507737, "end_pos": 106494310, "strand": "-", "evidence": [ { "database": "Ensembl Gene", "id": "ENSBTAG00000017125", "url": "https://www.ensembl.org/id/ENSBTAG00000017125" } ] } } ], "crossref": [ { "id": "F6RN21", "url": "https://alphafold.ebi.ac.uk/entry/F6RN21", "database": "AlphaFoldDB", "categories": [] }, { "id": "cd12378", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd12378", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "cd12379", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd12379", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "cd12380", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd12380", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "cd12381", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd12381", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "IPR000504", "url": "https://www.ebi.ac.uk/interpro/entry/IPR000504", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR002004", "url": "https://www.ebi.ac.uk/interpro/entry/IPR002004", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR003954", "url": "https://www.ebi.ac.uk/interpro/entry/IPR003954", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR006515", "url": "https://www.ebi.ac.uk/interpro/entry/IPR006515", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR012677", "url": "https://www.ebi.ac.uk/interpro/entry/IPR012677", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR034364", "url": "https://www.ebi.ac.uk/interpro/entry/IPR034364", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR035979", "url": "https://www.ebi.ac.uk/interpro/entry/IPR035979", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR036053", "url": "https://www.ebi.ac.uk/interpro/entry/IPR036053", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR045305", "url": "https://www.ebi.ac.uk/interpro/entry/IPR045305", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "PTHR24012", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR24012", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR46276", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR46276", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR46276:SF1", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR46276:SF1", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00076", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00076", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF00658", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00658", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "A0AAA9S3C5", "url": "https://www.uniprot.org/uniprotkb/A0AAA9S3C5", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0AAA9S3C5-1", "url": "https://www.uniprot.org/uniprotkb/A0AAA9S3C5-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0AAA9SYC3", "url": "https://www.uniprot.org/uniprotkb/A0AAA9SYC3", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0AAA9SYC3-1", "url": "https://www.uniprot.org/uniprotkb/A0AAA9SYC3-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0ABI0P5J3", "url": "https://www.uniprot.org/uniprotkb/A0ABI0P5J3", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0ABI0P5J3-1", "url": "https://www.uniprot.org/uniprotkb/A0ABI0P5J3-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "F6RN21", "url": "https://www.uniprot.org/uniprotkb/F6RN21", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "F6RN21-1", "url": "https://www.uniprot.org/uniprotkb/F6RN21-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MNAAASSYPMASLYVGDLHSDVTEAMLYEKFSPAGPVLSIRVCRDMITRRSLGYAYVNFQQPADAERALDTMNFDVIKGKPIRIMWSQRDPSLRKSGVGNVFIKNLDKSIDNKALYDTFSAFGNILSCKVVCDENGSKGYAFVHFETQEAADKAIEKMNGMLLNDRKVFVGRFKSRKEREAELGAKAKEFTNVYIKNFGEEVDDENLKELFSQFGKTLSVKVMRDPSGKSKGFGFVSYEKHEDANKAVEEMNGKEITGKVIFVGRAQKKVERQAELKRKFEQLKQERISRYQGVNLYIKNLDDTIDDEKLRKEFSPFGSITSAKVMLEDGRSKGFGFVCFSSPEEATKAVTEMNGRIVGSKPLYVALAQRKEERKAHLTNQYMQRVAGMRALPANAILNQFQPAAGGYFVPAVPQAQGRPPYYTPNQLAQMRPNPRWQQGGRPQGFQGMPSAIRQSGPRPALRHLAPTGNAPASRGLPTTAQRVGSECPDRLAMDFGGAGAAQQGLTDSCQSGGGVPTAVQNLAPRAAVAAAAAPRAVAPYKYASSIRSPHPAIQPLQAPQPAVHVQGQEPLTASMLAAAPPQEQKQMLGERLFPLIQTMHSNLAGKITGMLLEIDNSELLHMLESPESLRSKVDEAVAVLQAHHAKKEAAQKVGAVAAATS", "length": 662, "header": "tr|F6RN21-1|F6RN21_BOVIN Isoform 1 of Polyadenylate-binding protein OS=Bos taurus OX=9913 GN=PABPC4 PE=3 SV=1 CANONICAL=F6RN21-1" }, "isoforms": [ { "isoform_ac": "A0AAA9S3C5-1", "url": "https://www.uniprot.org/uniprotkb/A0AAA9S3C5/entry", "sequence": { "sequence": "MNAAASSYPMASLYVGDLHSDVTEAMLYEKFSPAGPVLSIRVCRDMITRRSLGYAYVNFQQPADAERALDTMNFDVIKGKPIRIMWSQRDPSLRKSGVGNVFIKNLDKSIDNKALYDTFSAFGNILSCKVVCDENGSKGYAFVHFETQEAADKAIEKMNGMLLNDRKVFVGRFKSRKEREAELGAKAKEFTNVYIKNFGEEVDDENLKELFSQFGKTLSVKVMRDPSGKSKGFGFVSYEKHEDANKAVEEMNGKEITGKVIFVGRAQKKVERQAELKRKFEQLKQERISRYQGVNLYIKNLDDTIDDEKLRKEFSPFGSITSAKVMLEDGRSKGFGFVCFSSPEEATKAVTEMNGRIVGSKPLYVALAQRKEERKAHLTNQYMQRVAGMRALPANAILNQFQPAAGGYFVPAVPQAQGRPPYYTPNQLAQMRPNPRWQQGGRPQGFQGMPSAIRQSGPRPALRHLAPTGSECPDRLAMDFGGAGAAQQGLTDSCQSGGGIGCTENGERWDLTGLCPDRWALISLVLLLRCSHSCAELSASCCCCCCCCSSGCCTLQICLQHPQSSPGHPAPAGTPACGPRAGAGAADRLHAGCSTPPGTEADAG", "length": 604, "header": "tr|A0AAA9S3C5-1|F6RN21_BOVIN Computationally mapped isoform of Polyadenylate-binding protein OS=Bos taurus OX=9913 GN=PABPC4 PE=3 SV=1 CANONICAL=F6RN21-1" }, "locus": { "chromosome": "3", "start_pos": 106506423, "end_pos": 106494454, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000110955.2", "url": "https://www.ensembl.org/id/ENSBTAT00000110955.2" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000080434.1", "url": "https://www.ensembl.org/id/ENSBTAP00000080434.1" } ] } }, { "isoform_ac": "A0AAA9SYC3-1", "url": "https://www.uniprot.org/uniprotkb/A0AAA9SYC3/entry", "sequence": { "sequence": "MVLQYEQRKSRQAVSHLSWGLSLQLCHTLKPEVMLEDGRSKGFGFVCFSSPEEATKAVTEMNGRIVGSKPLYVALAQRKEERKAHLTNQYMQRVAGMRALPANAILNQFQPAAGGYFVPAVPQAQGRPPYYTPNQLAQMRPNPRWQQGGRPQGFQGMPSAIRQSGPRPALRHLAPTGSECPDRLAMDFGGAGAAQQGLTDSCQSGGVPTAVQNLAPRAAVAAAAAPRAVAPYKYASSIRSPHPAIQPLQAPQPAVHVQGQEPLTASMLAAAPPQEQKQMLGERLFPLIQTMHSNLAGKITGMLLEIDNSELLHMLESPESLRSKVDEAVAVLQAHHAKKEAAQKVGAVAAATS", "length": 353, "header": "tr|A0AAA9SYC3-1|F6RN21_BOVIN Computationally mapped isoform of Polyadenylate-binding protein OS=Bos taurus OX=9913 GN=PABPC4 PE=3 SV=1 CANONICAL=F6RN21-1" }, "locus": { "chromosome": "3", "start_pos": 106506905, "end_pos": 106501884, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000116002.1", "url": "https://www.ensembl.org/id/ENSBTAT00000116002.1" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000090365.1", "url": "https://www.ensembl.org/id/ENSBTAP00000090365.1" } ] } }, { "isoform_ac": "A0ABI0P5J3-1", "url": "https://www.uniprot.org/uniprotkb/A0ABI0P5J3/entry", "sequence": { "sequence": "MNAAASSYPMASLYVGDLHSDVTEAMLYEKFSPAGPVLSIRVCRDMITRRSLGYAYVNFQQPADAERALDTMNFDVIKGKPIRIMWSQRDPSLRKSGVGNVFIKNLDKSIDNKALYDTFSAFGNILSCKVVCDENGSKGYAFVHFETQEAADKAIEKMNGMLLNDRKVFVGRFKSRKEREAELGAKAKEFTNVYIKNFGEEVDDENLKELFSQFGKTLSVKVMRDPSGKSKGFGFVSYEKHEDANKAVEEMNGKEITGKVIFVGRAQKKVERQAELKRKFEQLKQERISRYQGVNLYIKNLDDTIDDEKLRKEFSPFGSITSAKVMLEDGRSKGFGFVCFSSPEEATKAVTEMNGRIVGSKPLYVALAQRKEERKAHLTNQYMQRVAGMRALPANAILNQFQPAAGGYFVPAVPQAQGRPPYYTPNQLAQMRPNPRWQQGGRPQGFQGMPSAIRQSGPRPALRHLAPTGSECPDRLAMDFGGAGAAQQGLTDSCQSGGGIGCTENGERWDLTGLCPDRWALISLVLLLRCSHSCAELSASCCCCCCCCSSGCCTLQICLQHPQSSPGHPAPAGEVYQTEP", "length": 580, "header": "tr|A0ABI0P5J3-1|A0ABI0P5J3_BOVIN Computationally mapped isoform of Poly(A) binding protein cytoplasmic 4 OS=Bos taurus OX=9913 GN=PABPC4 PE=4 SV=1 CANONICAL=F6RN21-1" }, "locus": { "chromosome": "3", "start_pos": 106505112, "end_pos": 106494454, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000138616.1", "url": "https://www.ensembl.org/id/ENSBTAT00000138616.1" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000106184.1", "url": "https://www.ensembl.org/id/ENSBTAP00000106184.1" } ] } }, { "isoform_ac": "F6RN21-1", "url": "https://www.uniprot.org/uniprotkb/F6RN21/entry", "sequence": { "sequence": "MNAAASSYPMASLYVGDLHSDVTEAMLYEKFSPAGPVLSIRVCRDMITRRSLGYAYVNFQQPADAERALDTMNFDVIKGKPIRIMWSQRDPSLRKSGVGNVFIKNLDKSIDNKALYDTFSAFGNILSCKVVCDENGSKGYAFVHFETQEAADKAIEKMNGMLLNDRKVFVGRFKSRKEREAELGAKAKEFTNVYIKNFGEEVDDENLKELFSQFGKTLSVKVMRDPSGKSKGFGFVSYEKHEDANKAVEEMNGKEITGKVIFVGRAQKKVERQAELKRKFEQLKQERISRYQGVNLYIKNLDDTIDDEKLRKEFSPFGSITSAKVMLEDGRSKGFGFVCFSSPEEATKAVTEMNGRIVGSKPLYVALAQRKEERKAHLTNQYMQRVAGMRALPANAILNQFQPAAGGYFVPAVPQAQGRPPYYTPNQLAQMRPNPRWQQGGRPQGFQGMPSAIRQSGPRPALRHLAPTGNAPASRGLPTTAQRVGSECPDRLAMDFGGAGAAQQGLTDSCQSGGGVPTAVQNLAPRAAVAAAAAPRAVAPYKYASSIRSPHPAIQPLQAPQPAVHVQGQEPLTASMLAAAPPQEQKQMLGERLFPLIQTMHSNLAGKITGMLLEIDNSELLHMLESPESLRSKVDEAVAVLQAHHAKKEAAQKVGAVAAATS", "length": 662, "header": "tr|F6RN21-1|F6RN21_BOVIN Isoform 1 of Polyadenylate-binding protein OS=Bos taurus OX=9913 GN=PABPC4 PE=3 SV=1 CANONICAL=F6RN21-1" }, "locus": { "chromosome": "3", "start_pos": 106506905, "end_pos": 106494454, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000022761.7", "url": "https://www.ensembl.org/id/ENSBTAT00000022761.7" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000022761.5", "url": "https://www.ensembl.org/id/ENSBTAP00000022761.5" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [], "orthologs": [], "go_annotation": { "categories": [ { "name": "Molecular Function", "total": 1, "go_terms": [ { "name": "RNA binding", "id": "GO:0003723", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003723", "evidence": [ { "database": "UniProtKB", "id": "F6RN21", "url": "https://www.uniprot.org/uniprotkb/F6RN21" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 1, "go_terms": [ { "name": "cytoplasm", "id": "GO:0005737", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005737", "evidence": [ { "database": "UniProtKB", "id": "F6RN21", "url": "https://www.uniprot.org/uniprotkb/F6RN21" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 135, "end_pos": 137, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "F6RN21", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F6RN21" }, { "id": "PS51309", "database": "PROSITE", "url": "https://prosite.expasy.org/PS51309" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "PABC", "eco_id": "ECO_0000259", "start_pos": 569, "end_pos": 646, "start_aa": "Gln", "end_aa": "Ala", "glycosite_overlap": [] }, { "evidence": [ { "id": "F6RN21", "database": 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"evidence": [ { "id": "G3X7Q0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3X7Q0/entry#names_and_taxonomy" } ] }, { "name": "CIN85-associated multi-domain-containing Rho GTPase-activating protein 1", "type": "synonym", "evidence": [ { "id": "G3X7Q0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3X7Q0/entry#names_and_taxonomy" } ] }, { "name": "Rho-type GTPase-activating protein 27", "type": "synonym", "evidence": [ { "id": "G3X7Q0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3X7Q0/entry#names_and_taxonomy" } ] }, { "name": "rho GTPase-activating protein 27 isoform X2", "type": "synonym", "evidence": [ { "id": "XP_024836314", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_024836314" } ] } ], "function": [ { "annotation": "Rho GTPase-activating protein which may be involved in clathrin-mediated endocytosis. GTPase activators for the Rho-type GTPases act by converting them to an inactive GDP-bound state. Has activity toward CDC42 and RAC1.", "evidence": [ { "database": "UniProtKB", "id": "A0AAA9S879", "url": "https://www.uniprot.org/uniprotkb/A0AAA9S879#function" }, { "database": "UniProtKB", "id": "ARBA00057721", "url": "https://www.uniprot.org/uniprotkb/ARBA00057721#function" }, { "database": "UniProtKB", "id": "G3X7Q0", "url": "https://www.uniprot.org/uniprotkb/G3X7Q0#function" }, { "database": "UniProtKB", "id": "A0AAF6DM85", "url": "https://www.uniprot.org/uniprotkb/A0AAF6DM85#function" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Bos taurus", "taxid": 9913, "evidence": [ { "database": "UniProtKB", "id": "G3X7Q0", "url": "https://www.uniprot.org/uniprotkb/G3X7Q0" } ], "common_name": "Bovine", "glygen_name": "Bovine", "reference_species": "Bos taurus [9913]" } ], "gene": [ { "name": "ARHGAP27", "url": "https://www.uniprot.org/uniprotkb/G3X7Q0", "locus": { "chromosome": "19", "start_pos": 45042255, "end_pos": 45078358, "strand": "+", "evidence": [ { "database": "Ensembl Gene", "id": "ENSBTAG00000000571", "url": "https://www.ensembl.org/id/ENSBTAG00000000571" } ] } } ], "crossref": [ { "id": "G3X7Q0", "url": "https://alphafold.ebi.ac.uk/entry/G3X7Q0", "database": "AlphaFoldDB", "categories": [] }, { "id": "ENSBTAG00000054347", "url": "https://bgee.org/?page=gene&gene_id=ENSBTAG00000054347", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "cd00201", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd00201", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "cd04403", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd04403", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "cd12069", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd12069", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "cd13233", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd13233", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "789296", "url": "https://www.ncbi.nlm.nih.gov/gene/789296", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR000198", "url": "https://www.ebi.ac.uk/interpro/entry/IPR000198", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR001202", "url": "https://www.ebi.ac.uk/interpro/entry/IPR001202", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR001452", "url": "https://www.ebi.ac.uk/interpro/entry/IPR001452", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR001849", "url": "https://www.ebi.ac.uk/interpro/entry/IPR001849", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR008936", "url": "https://www.ebi.ac.uk/interpro/entry/IPR008936", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR011993", "url": "https://www.ebi.ac.uk/interpro/entry/IPR011993", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR036020", "url": "https://www.ebi.ac.uk/interpro/entry/IPR036020", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR036028", "url": "https://www.ebi.ac.uk/interpro/entry/IPR036028", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR050729", "url": "https://www.ebi.ac.uk/interpro/entry/IPR050729", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "PTHR23176", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR23176", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR23176:SF104", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR23176:SF104", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00169", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00169", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF00397", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00397", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF00620", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00620", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "XP_024836314", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_024836314", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0AAA9S879", "url": "https://www.uniprot.org/uniprotkb/A0AAA9S879", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0AAA9S879-1", "url": "https://www.uniprot.org/uniprotkb/A0AAA9S879-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0AAF6DM85", "url": "https://www.uniprot.org/uniprotkb/A0AAF6DM85", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0AAF6DM85-1", "url": "https://www.uniprot.org/uniprotkb/A0AAF6DM85-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "G3X7Q0", "url": "https://www.uniprot.org/uniprotkb/G3X7Q0", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "G3X7Q0-1", "url": "https://www.uniprot.org/uniprotkb/G3X7Q0-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MAADVEGDVYVLVEHPFEYTGKDGRRVAIQPNERYRLLRRSTEHWWHVRSEPGGRPFYLPAQYVRELPALGHPAPAPPPPAPLQGPAAPEPLAYDYRFMSASAPSGPDGAPAEPRGRAGSLCGRARPGAATQRRSLAPGSPACLYTRPAAPVRPAQSLDDLARTAAPPAGLLGSGGGFKACSVAGSWVCPRPLARSDSENVYEAIQDVRDPPTEQRPEQVDEPPEPVYANVERQPPATLPRASAAPRGVGDSVWETHTDAGTGRPYYYNPDTGVTTWESPFEATEGAASPATSPASVGSHESLETEWGQYWDEESHRVFFYNSLTGETAWEDELEDQLEDEQEMQPGLGPSNQRPPTPETDYPDLLTSYPEEDYSPVGSFSEPGPASPFVTPPGWSCHVSPDGQTVYTNNITEEQWVRLENQHGKTYFYNPDDASVQWALPQVPVPVPAPRNSHKSNQNSETPAQATPPEEKIKTLDKAGVLHRTKIVDKGKRLRKKHWSASWTVLEGGILTFFKDSKNSAASGLRQPSKLSTPEFTVDLKGASLTWAPKDKSSKKNVLELRSRDGSEYLIQHDSEAIISTWHSAITQGIQEMSADLPPEEESENSGVDFRSSERLGSWQEDEPRPGAAPSTPGPGGLEGDVSKVRQKLLRFLLRRPTLQSLREKGYIKDQVFGCPLAELCEREKSSVPRFVQQSIRAVEARGLDIDGLYRISGNLATIQKLRYKVDHDERLDLEDGHWEDVHVITGALKLFFRELPEPLFPFSHFRQFLAAIKLQDPATRFRCVRDLVRSLPAPNHDTLRVLFQHLCRVIEHGERNRMSVQNVAIVFGPTLLRPETEEASMPMTMVFQNQVVELILQQCSDIFPPH", "length": 867, "header": "tr|G3X7Q0-1|G3X7Q0_BOVIN Isoform 1 of Rho GTPase-activating protein 27 OS=Bos taurus OX=9913 GN=ARHGAP27 PE=4 SV=3 CANONICAL=G3X7Q0-1" }, "isoforms": [ { "isoform_ac": "A0AAA9S879-1", "url": "https://www.uniprot.org/uniprotkb/A0AAA9S879/entry", "sequence": { "sequence": "MAADVEGDVYVLVEHPFEYTGKDGRRVAIQPNERYRLLRRSTEHWWHVRSEPGGRPFYLPAQYVRELPALGHPAPAPPPPAPLQGPAAPEPLAYDYRFMSASAPSGPDGAPAEPRGRAGSLCGRARPGAATQRRSLAPGSPACLYTRPAAPVRPAQSLDDLARTAAPPAGLLGSGGGFKACSVAGSWVCPRPLARSDSENVYEAIQDVRDPPTEQRPEQAGCGGHTGEISGKILNLTPELSPKGGIGVSQVDEPPEPVYANVERQPPATLPRASAAPRGVGDSVWETHTDAGTGRPYYYNPDTGVTTWESPFEATEGAASPATSPASVGSHESLETEWGQYWDEESHRVFFYNSLTGETAWEDELEDQLEDEQEMQPGLGPSNQRPPTPETDYPDLLTSYPEEDYSPVGSFSEPGPASPFVTPPGWSCHVSPDGQTVYTNNITEEQWVRLENQHGKTYFYNPDDASVQWALPQVPVPVPAPRNSHKSNQNSETPAQATPPEEKIKTLDKAGVLHRTKIVDKGKRLRKKHWSASWTVLEGGILTFFKDSKNSAASGLRQPSKLSTPEFTVDLKGASLTWAPKDKSSKKNVLELRSRDGSEYLIQHDSEAIISTWHSAITQGIQEMSADLPPEEESENSGVDFRSSERLGSWQEDEPRPGAAPSTPGPGGLEGDVSKVRQKLLRFLLRRPTLQSLREKGYIKDQVFGCPLAELCEREKSSVPRFVQQSIRAVEARGLDIDGLYRISGNLATIQKLRYKVDHDERLDLEDGHWEDVHVITGALKLFFRELPEPLFPFSHFRQFLAAIKLQDPATRFRCVRDLVRSLPAPNHDTLRVLFQHLCRVIEHGERNRMSVQNVAIVFGPTLLRPETEEASMPMTMVFQNQVVELILQQCSDIFPPH", "length": 898, "header": "tr|A0AAA9S879-1|G3X7Q0_BOVIN Computationally mapped isoform of Rho GTPase-activating protein 27 OS=Bos taurus OX=9913 GN=ARHGAP27 PE=4 SV=1 CANONICAL=G3X7Q0-1" }, "locus": { "chromosome": "19", "start_pos": 45075870, "end_pos": 45043875, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000119451.1", "url": "https://www.ensembl.org/id/ENSBTAT00000119451.1" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000081447.1", "url": "https://www.ensembl.org/id/ENSBTAP00000081447.1" } ] } }, { "isoform_ac": "A0AAF6DM85-1", "url": "https://www.uniprot.org/uniprotkb/A0AAF6DM85/entry", "sequence": { "sequence": "MVDITAKLTKRQSRDLRGQVDEPPEPVYANVERQPPATLPRASAAPRGVGDSVWETHTDAGTGRPYYYNPDTGVTTWESPFEATEGAASPATSPASVGSHESLETEWGQYWDEESHRVFFYNSLTGETAWEDELEDQLEDEQEMQPGLGPSNQRPPTPETDYPDLLTSYPEEDYSPVGSFSEPGPASPFVTPPGWSCHVSPDGQTVYTNNITEEQWVRLENQHGKTYFYNPDDASVQWALPQVPVPVPAPRNSHKSNQNSETPAQATPPEEKIKTLDKAGVLHRTKIVDKGKRLRKKHWSASWTVLEGGILTFFKDSKNSAASGLRQPSKLSTPEFTVDLKGASLTWAPKDKSSKKNVLELRSRDGSEYLIQHDSEAIISTWHSAITQGIQEMSADLPPEEESENSGVDFRSSERLGSWQEDEPRPGAAPSTPGPGGLEGDVSKVRQKLLRFLLRRPTLQSLREKGYIKDQVFGCPLAELCEREKSSVPRFVQQSIRAVEARGLDIDGLYRISGNLATIQKLRYKVDHDERLDLEDGHWEDVHVITGALKLFFRELPEPLFPFSHFRQFLAAIKLQDPATRFRCVRDLVRSLPAPNHDTLRVLFQHLCRVIEHGERNRMSVQNVAIVFGPTLLRPETEEASMPMTMVFQNQVVELILQQCSDIFPPH", "length": 667, "header": "tr|A0AAF6DM85-1|A0AAF6DM85_BOVIN Computationally mapped isoform of Rho GTPase-activating protein 27 OS=Bos taurus OX=9913 GN=ARHGAP27 PE=4 SV=2 CANONICAL=G3X7Q0-1" }, "locus": { "chromosome": "19", "start_pos": 45057599, "end_pos": 45043875, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000064712.4", "url": "https://www.ensembl.org/id/ENSBTAT00000064712.4" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000055885.4", "url": "https://www.ensembl.org/id/ENSBTAP00000055885.4" } ] } }, { "isoform_ac": "G3X7Q0-1", "url": "https://www.uniprot.org/uniprotkb/G3X7Q0/entry", "sequence": { "sequence": "MAADVEGDVYVLVEHPFEYTGKDGRRVAIQPNERYRLLRRSTEHWWHVRSEPGGRPFYLPAQYVRELPALGHPAPAPPPPAPLQGPAAPEPLAYDYRFMSASAPSGPDGAPAEPRGRAGSLCGRARPGAATQRRSLAPGSPACLYTRPAAPVRPAQSLDDLARTAAPPAGLLGSGGGFKACSVAGSWVCPRPLARSDSENVYEAIQDVRDPPTEQRPEQVDEPPEPVYANVERQPPATLPRASAAPRGVGDSVWETHTDAGTGRPYYYNPDTGVTTWESPFEATEGAASPATSPASVGSHESLETEWGQYWDEESHRVFFYNSLTGETAWEDELEDQLEDEQEMQPGLGPSNQRPPTPETDYPDLLTSYPEEDYSPVGSFSEPGPASPFVTPPGWSCHVSPDGQTVYTNNITEEQWVRLENQHGKTYFYNPDDASVQWALPQVPVPVPAPRNSHKSNQNSETPAQATPPEEKIKTLDKAGVLHRTKIVDKGKRLRKKHWSASWTVLEGGILTFFKDSKNSAASGLRQPSKLSTPEFTVDLKGASLTWAPKDKSSKKNVLELRSRDGSEYLIQHDSEAIISTWHSAITQGIQEMSADLPPEEESENSGVDFRSSERLGSWQEDEPRPGAAPSTPGPGGLEGDVSKVRQKLLRFLLRRPTLQSLREKGYIKDQVFGCPLAELCEREKSSVPRFVQQSIRAVEARGLDIDGLYRISGNLATIQKLRYKVDHDERLDLEDGHWEDVHVITGALKLFFRELPEPLFPFSHFRQFLAAIKLQDPATRFRCVRDLVRSLPAPNHDTLRVLFQHLCRVIEHGERNRMSVQNVAIVFGPTLLRPETEEASMPMTMVFQNQVVELILQQCSDIFPPH", "length": 867, "header": "tr|G3X7Q0-1|G3X7Q0_BOVIN Isoform 1 of Rho GTPase-activating protein 27 OS=Bos taurus OX=9913 GN=ARHGAP27 PE=4 SV=3 CANONICAL=G3X7Q0-1" }, "locus": { "chromosome": "19", "start_pos": 45075870, "end_pos": 45043875, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000000749.6", "url": "https://www.ensembl.org/id/ENSBTAT00000000749.6" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000040418.5", "url": "https://www.ensembl.org/id/ENSBTAP00000040418.5" } ] } } ], "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "other", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 467, "start_aa": "Thr", "end_pos": 467, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr467", "evidence": [ { "id": "", "database": "GlyGen", "url": "https://data.glygen.org/" } ], "filter_code": "000000000000000010000.00000000001000.0.01000" }, { "glytoucan_ac": "", "type": "O-linked", "subtype": "other", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 632, "start_aa": "Thr", "end_pos": 632, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr632", "evidence": [ { "id": "", "database": "GlyGen", "url": "https://data.glygen.org/" } ], "filter_code": "000000000000000010000.00000000001000.0.01000" } ], "phosphorylation": [], "glycation": [], "keywords": [ "glycoprotein", "glycoprotein_predicted" ], "publication": [], "pathway": [], "orthologs": [], "go_annotation": { "categories": [ { "name": "Molecular Function", "total": 1, "go_terms": [ { "name": "GTPase activator activity", "id": "GO:0005096", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005096", "evidence": [ { "database": "UniProtKB", "id": "G3X7Q0", "url": "https://www.uniprot.org/uniprotkb/G3X7Q0" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 3, "go_terms": [ { "name": "cytoplasm", "id": "GO:0005737", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005737", "evidence": [ { "database": "UniProtKB", "id": "G3X7Q0", "url": "https://www.uniprot.org/uniprotkb/G3X7Q0" } ], "pmid": "" }, { "name": "membrane", "id": "GO:0016020", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016020", "evidence": [ { "database": "UniProtKB", "id": "G3X7Q0", "url": "https://www.uniprot.org/uniprotkb/G3X7Q0" } ], "pmid": "" }, { "name": "plasma membrane", "id": "GO:0005886", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005886", "evidence": [ { "database": "UniProtKB", "id": "G3X7Q0", "url": "https://www.uniprot.org/uniprotkb/G3X7Q0" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 3, "go_terms": [ { "name": "endocytosis", "id": "GO:0006897", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006897", "evidence": [ { "database": "UniProtKB", "id": "G3X7Q0", "url": "https://www.uniprot.org/uniprotkb/G3X7Q0" } ], "pmid": "" }, { "name": "signal transduction", "id": "GO:0007165", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007165", "evidence": [ { "database": "UniProtKB", "id": "G3X7Q0", "url": "https://www.uniprot.org/uniprotkb/G3X7Q0" } ], "pmid": "" }, { "name": "small GTPase-mediated signal transduction", "id": "GO:0007264", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007264", "evidence": [ { "database": "UniProtKB", "id": "G3X7Q0", "url": "https://www.uniprot.org/uniprotkb/G3X7Q0" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 410, "end_pos": 412, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "G3X7Q0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3X7Q0" }, { "id": "PS50003", "database": "PROSITE", "url": "https://prosite.expasy.org/PS50003" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "PH", "eco_id": "ECO_0000259", "start_pos": 475, "end_pos": 591, "start_aa": "Thr", "end_aa": "Gln", "glycosite_overlap": [] }, { "evidence": [ { "id": "G3X7Q0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3X7Q0" }, { "id": "PS50238", "database": "PROSITE", "url": "https://prosite.expasy.org/PS50238" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "Rho-GAP", "eco_id": "ECO_0000259", "start_pos": 675, "end_pos": 864, "start_aa": "Cys", "end_aa": "Phe", "glycosite_overlap": [] }, { "evidence": [ { "id": "G3X7Q0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3X7Q0" }, { "id": "PS50002", "database": "PROSITE", "url": "https://prosite.expasy.org/PS50002" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": 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"categories": [ "Protein Classification" ] }, { "id": "PF14816", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF14816", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "A0AAA9S9P8", "url": "https://www.uniprot.org/uniprotkb/A0AAA9S9P8", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0AAA9S9P8-1", "url": "https://www.uniprot.org/uniprotkb/A0AAA9S9P8-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0AAA9SGG7", "url": "https://www.uniprot.org/uniprotkb/A0AAA9SGG7", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0AAA9SGG7-1", "url": "https://www.uniprot.org/uniprotkb/A0AAA9SGG7-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0AAA9TWV8", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TWV8", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0AAA9TWV8-1", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TWV8-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "G3MZY2", "url": "https://www.uniprot.org/uniprotkb/G3MZY2", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "G3MZY2-1", "url": "https://www.uniprot.org/uniprotkb/G3MZY2-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MAGPRKAVLDLPWREDDQAATTRPILLPSLKGSCFDHPLYQGLPHPTRRLCSPASAPASKSSKKPKMKATGNTVSNDWSPPPVEFLNLSVPQAKKGDPAPGPRGLRRLAVQHPEVSEQEPQDLDRLGGLPSLGELFWNVAGTSPEAATPGMGAHTSLASGSSGCYVNSLDYLLQEKREQEQEKLLFLDYADLRAWDLNEDEVLLTPEHRTLVERFSVPPQAIPAVHPGETVFLPRHHPVPCILDSSQLKPRNPLEKLFLRSSPARQLTFLRQGLLSSVYLPVGDRPIPLFRWLLQLLTWPPETSSRAFGLLWDLSLDGLFRQSDGNTNLWCPSLREVSATFHNLGAHSPTLQPLGPTQHTGSEASLSHSEQQDALQEVALDSSLNYICKFLTLCALAQPGAYTDQNLLDLIELLCRAGLDTRLRLLPKTDLQQLLLQLLENIREWPEKLRQLCCALSRASDHHHNLLALVQLFLDVSPRSRQLRGQLSLLVMARLLNQQERLSLWQEKAQLSSLCQLLSLMRPSSLRRYLGPETVLPGQEQQPKASAQLDHKACYLCHSLLTLAGVVVSCQDITPDQWGELQLLCMQLDRHINTHIRESPQAMHQTTLKDLAAQTYIRWQELLAHCQPQLSCRLEVGLPLRWEEHTQAALLLLLLSHFSHVRLCATPETVAHQAPPSL", "length": 678, "header": "tr|G3MZY2-1|G3MZY2_BOVIN Isoform 1 of Family with sequence similarity 178 member B OS=Bos taurus OX=9913 GN=FAM178B PE=3 SV=3 CANONICAL=G3MZY2-1" }, "isoforms": [ { "isoform_ac": "A0AAA9S9P8-1", "url": "https://www.uniprot.org/uniprotkb/A0AAA9S9P8/entry", "sequence": { "sequence": "MAGPRKAVLDLPWREDDQAATTRPILLPSLKGSCFDHPLYQGLPHPTRRLCSPASAPASKSSKKPKMKATGNTVSNDWSPPPVEFLNLSVPQAKKGDPAPGPRGLRRLAVQHPEVSEQEPQDLDRLGGLPSLGELFWNVAGTSPEAATPGMGAHTSLASGSSGCYVNSLDYLLQEKREQEQEKLLFLDYADLRAWDLNEDEVLLTPEHRTLVERFSVPPQAIPAVHPGETVFLPRHHPVPCILDSSQLKPRNPLEKLFLRSSPARQLTFLRQGLLSSVYLPVGDRPIPLFRWLLQLLTWPPETSSRAFGLLWDLSLDGLFRQSDGNTNLWCPSLREVSATFHNLGAHSPTLQPLGPTQHTGSEASLSHSEQQDALQEVALDSSLNYICKFLTLCALAQPGAYTDQNLLDLIELLCRAGLDTRLRLLPKTDLQQLLLQLLENIREWPEKLRQLCCALSRASDHHHNLLALVQLFLDVSPRSRQLRGQLSLLVMARLLNQQERLSLWQEKAQLSSLCQLLSLMRPSSLRRYLGPETVLPGQEQQPKASAQLDHKGEDRAASRLWSREGGIQHSSSQKSPPTRPRRWKPQAPLAAVERDRPFLSALGSGTSRVSDSASPQVVD", "length": 620, "header": "tr|A0AAA9S9P8-1|G3MZY2_BOVIN Computationally mapped isoform of Family with sequence similarity 178 member B OS=Bos taurus OX=9913 GN=FAM178B PE=3 SV=1 CANONICAL=G3MZY2-1" }, "locus": { "chromosome": "11", "start_pos": 2929816, "end_pos": 2839037, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000103776.1", "url": "https://www.ensembl.org/id/ENSBTAT00000103776.1" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000082808.1", "url": "https://www.ensembl.org/id/ENSBTAP00000082808.1" } ] } }, { "isoform_ac": "A0AAA9SGG7-1", "url": "https://www.uniprot.org/uniprotkb/A0AAA9SGG7/entry", "sequence": { "sequence": "MLSRVKLFSWRGKTWEQPARCPVGPCLPPPLPRVLAGVELPAGGLLLGLWAAKLALCVHSCEPGAGRTVVETIHRLGRPEQGSTALVLLSSLCQLLSLMRPSSLRRYLGPETVLPGQEQQPKASAQLDHKACYLCHSLLTLAGVVVSCQDITPDQWGELQLLCMQLDRHINTHIRESPQAMHQTTLKDLAAQTYIRWQELLAHCQPQAQYFSLWEGV", "length": 217, "header": "tr|A0AAA9SGG7-1|G3MZY2_BOVIN Computationally mapped isoform of Family with sequence similarity 178 member B OS=Bos taurus OX=9913 GN=FAM178B PE=3 SV=1 CANONICAL=G3MZY2-1" }, "locus": { "chromosome": "11", "start_pos": 2852797, "end_pos": 2831253, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000104616.1", "url": "https://www.ensembl.org/id/ENSBTAT00000104616.1" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000084456.1", "url": "https://www.ensembl.org/id/ENSBTAP00000084456.1" } ] } }, { "isoform_ac": "A0AAA9TWV8-1", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TWV8/entry", "sequence": { "sequence": "MAGPRKAVLDLPWREDDQAATTRPILLPSLKGSCFDHPLYQGLPHPTRRLCSPASAPASKSSKKPKMKATGNTVSNDWSPPPVEFLNLSVPQAKKGDPAPGPRGLRRLAVQHPEVSEQEPQDLDRLGGLPSLGELFWNVAGTSPEAATPGMGAHTSLASGSSGCYVNSLDYLLQEKREQEQEKLLFLDYADLRAWDLNEDEVLLTPEHRTLVERFSVPPQAIPAVHPGETVFLPRHHPVPCILDSSQLKPRNPLEKLFLRSSPARQLTFLRQGLLSSVYLPVGDRPIPLFRWLLQLLTWPPETSSRAFGLLWDLSLDGLFRQSDGNTNLWCPSLREVSATFHNLGAHSPTLQPLGPTQHTGSEASLSHSEQQDALQEVALDSSLNYICKFLTLCALAQPGAYTDQNLLDLIELLCRAGLDTRLRLLPKTDLQQLLLQLLENIREWPEKLRQLCCALSRASDHHHNLLALVQLFLDVSPRSRQLRGQLSLLVMARLLNQQERLSLWQEKAQLSSLCQLLSLMRPSSLRRYLGPETVLPGQEQQPKASAQLDHKACYLCHSLLTLAGVVVSCQDITPDQWGELQLLCMQLDRHINTHIRESPQAMHQTTLKDLAAQTYIRWQELLAHCQPQAQYFSLWEGV", "length": 639, "header": "tr|A0AAA9TWV8-1|A0AAA9TWV8_BOVIN Computationally mapped isoform of Family with sequence similarity 178 member B OS=Bos taurus OX=9913 GN=FAM178B PE=3 SV=1 CANONICAL=G3MZY2-1" }, "locus": { "chromosome": "11", "start_pos": 2929816, "end_pos": 2831253, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000133401.1", "url": "https://www.ensembl.org/id/ENSBTAT00000133401.1" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000101076.1", "url": "https://www.ensembl.org/id/ENSBTAP00000101076.1" } ] } }, { "isoform_ac": "G3MZY2-1", "url": "https://www.uniprot.org/uniprotkb/G3MZY2/entry", "sequence": { "sequence": "MAGPRKAVLDLPWREDDQAATTRPILLPSLKGSCFDHPLYQGLPHPTRRLCSPASAPASKSSKKPKMKATGNTVSNDWSPPPVEFLNLSVPQAKKGDPAPGPRGLRRLAVQHPEVSEQEPQDLDRLGGLPSLGELFWNVAGTSPEAATPGMGAHTSLASGSSGCYVNSLDYLLQEKREQEQEKLLFLDYADLRAWDLNEDEVLLTPEHRTLVERFSVPPQAIPAVHPGETVFLPRHHPVPCILDSSQLKPRNPLEKLFLRSSPARQLTFLRQGLLSSVYLPVGDRPIPLFRWLLQLLTWPPETSSRAFGLLWDLSLDGLFRQSDGNTNLWCPSLREVSATFHNLGAHSPTLQPLGPTQHTGSEASLSHSEQQDALQEVALDSSLNYICKFLTLCALAQPGAYTDQNLLDLIELLCRAGLDTRLRLLPKTDLQQLLLQLLENIREWPEKLRQLCCALSRASDHHHNLLALVQLFLDVSPRSRQLRGQLSLLVMARLLNQQERLSLWQEKAQLSSLCQLLSLMRPSSLRRYLGPETVLPGQEQQPKASAQLDHKACYLCHSLLTLAGVVVSCQDITPDQWGELQLLCMQLDRHINTHIRESPQAMHQTTLKDLAAQTYIRWQELLAHCQPQLSCRLEVGLPLRWEEHTQAALLLLLLSHFSHVRLCATPETVAHQAPPSL", "length": 678, "header": "tr|G3MZY2-1|G3MZY2_BOVIN Isoform 1 of Family with sequence similarity 178 member B OS=Bos taurus OX=9913 GN=FAM178B PE=3 SV=3 CANONICAL=G3MZY2-1" }, "locus": { "chromosome": "11", "start_pos": 2929816, "end_pos": 2832629, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000065582.3", "url": "https://www.ensembl.org/id/ENSBTAT00000065582.3" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000055136.3", "url": "https://www.ensembl.org/id/ENSBTAP00000055136.3" } ] } } ], "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "other", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 148, "start_aa": "Thr", "end_pos": 148, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr148", "evidence": [ { "id": "", "database": "GlyGen", "url": "https://data.glygen.org/" } ], "filter_code": "000000000000000010000.00000000001000.0.01000" } ], "phosphorylation": [], "glycation": [], "keywords": [ "glycoprotein", "glycoprotein_predicted" ], "publication": [], "pathway": [ { "id": "bta:618158", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?bta:618158", "resource": "KEGG Pathway" } ], "orthologs": [], "go_annotation": {}, "pro_annotation": [], "site_annotation": [ { "start_pos": 87, "end_pos": 89, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [ { "pdb_id": "AF-G3MZY2-F1", "pdb_chain": "global", "start_pos": 1, "end_pos": 678, "overlap": "1.0", "method": "AlphaFold", "type": "alphafold", "resolution": -1.0, "url": "https://data.glygen.org/ln2downloads/pdb/current/AF-G3MZY2-F1.pdb", "url_external": "https://alphafold.ebi.ac.uk/entry/G3MZY2" } ], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "G3MZY2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3MZY2" }, { "id": "PF14816", "database": "Pfam", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF14816" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "Coiled-coil SMC6 And NSE5 INteracting (CANIN)", "eco_id": "ECO_0000259", "start_pos": 158, "end_pos": 500, "start_aa": "Ala", "end_aa": "Glu", "glycosite_overlap": [] } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [ 148 ], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 87, "end_pos": 89 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 1 }, { "field": "total_sites", "count": 1 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 1 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { 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"total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ], "tool_support": { "graph_view": "yes" } }, { "uniprot_canonical_ac": "G3MYU9-1", "uniprot_ac": "G3MYU9", "uniprot_id": "G3MYU9_BOVIN", "mass": { "chemical_mass": 47153.0, "monoisotopic_mass": 47153.0 }, "refseq": { "ac": "XP_002698264", "name": "neuronal pentraxin-2", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_002698264" }, "gene_names": [ { "name": "NPTX2", "type": "recommended", "evidence": [ { "id": "G3MYU9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3MYU9" } ] }, { "name": "NPTX2", "type": "synonym", "evidence": [ { "id": "XP_002698264", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_002698264" } ] } ], "protein_names": [ { "name": "Neuronal pentraxin 2", "type": "synonym", "evidence": [ { "id": "G3MYU9", "database": "UniProtKB", "url": 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"Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "XP_002698264", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_002698264", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0AAA9SAB8", "url": "https://www.uniprot.org/uniprotkb/A0AAA9SAB8", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0AAA9SAB8-1", "url": "https://www.uniprot.org/uniprotkb/A0AAA9SAB8-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "G3MYU9", "url": "https://www.uniprot.org/uniprotkb/G3MYU9", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "G3MYU9-1", "url": "https://www.uniprot.org/uniprotkb/G3MYU9-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MLALLAAGVVLAVAAGAQDGPAPSNRFVCTALPPEAARAGCPLPAMPMQGGALSPEEELRAAVLQLRETVVQQKETLGSQREAIRELTAKLARCEGLAGGKAPGRAASGKDTMGDLPRDPGHVVEQLSRSLQTLKDRLESLEHQLRANVSNAVLPGDFREVLQRRLGELERQLLRKVAELEDEKSLLHNETSAHRQKTESALNALLQRVTELERGNSAFKSPDAFKVSLPLRTNYLYGKIKKTLPELYAFTICLWLRSSASPGIGTPFSYAVPGQANEIVLIEWGNNPIELLINDKVAQLPLFVSDGKWHHICVTWTTRDGMWEAFQDGEKLGTGENLAPWHPIKPGGVLILGQEQDTVGGRFDATQAFVGELSQFNIWDRVLRAQEIINIANCSTNMPGNIIPWVDNNVDVFGGASKWPVETCEERLLDL", "length": 431, "header": "tr|G3MYU9-1|G3MYU9_BOVIN Isoform 1 of Neuronal pentraxin 2 OS=Bos taurus OX=9913 GN=NPTX2 PE=4 SV=2 CANONICAL=G3MYU9-1" }, "isoforms": [ { "isoform_ac": "A0AAA9SAB8-1", "url": "https://www.uniprot.org/uniprotkb/A0AAA9SAB8/entry", "sequence": { "sequence": "MLALLAAGVVLAVAAGAQDGPAPSNRFVCTALPPEAARAGCPLPAMPMQGGALSPEEELRAAVLQLRETVVQQKETLGSQREAIRELTAKLARCEGLAGGKAPGRAASGKDTMGDLPRDPGHVVEQLSRSLQTLKDRLESLEHQLRANVSNAVLPGDFREVLQRRLGELERQLLRKVAELEDEKSLLHNETSAHRQKTESALNALLQRVTELERGNSAFKSPDAFKVSLPLRTNYLYGKIKKTLPELYAFTICLWLRSSASPGIGTPFSYAVPGQANEIVLIEWGNNPIELLINDKEHGLLKRSALGVCGTLLQPHLNVAQLPLFVSDGKWHHICVTWTTRDGMWEAFQDGEKLGTGENLAPWHPIKPGGVLILGQEQDTVGGRFDATQAFVGELSQFNIWDRVLRAQEIINIANCSTNMPGNIIPWVDNNVDVFGGASKWPVETCEERLLDL", "length": 453, "header": "tr|A0AAA9SAB8-1|G3MYU9_BOVIN Computationally mapped isoform of Neuronal pentraxin 2 OS=Bos taurus OX=9913 GN=NPTX2 PE=4 SV=1 CANONICAL=G3MYU9-1" }, "locus": { "chromosome": "25", "start_pos": 37512061, "end_pos": 37501338, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000102137.1", "url": "https://www.ensembl.org/id/ENSBTAT00000102137.1" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000080371.1", "url": "https://www.ensembl.org/id/ENSBTAP00000080371.1" } ] } }, { "isoform_ac": "G3MYU9-1", "url": "https://www.uniprot.org/uniprotkb/G3MYU9/entry", "sequence": { "sequence": "MLALLAAGVVLAVAAGAQDGPAPSNRFVCTALPPEAARAGCPLPAMPMQGGALSPEEELRAAVLQLRETVVQQKETLGSQREAIRELTAKLARCEGLAGGKAPGRAASGKDTMGDLPRDPGHVVEQLSRSLQTLKDRLESLEHQLRANVSNAVLPGDFREVLQRRLGELERQLLRKVAELEDEKSLLHNETSAHRQKTESALNALLQRVTELERGNSAFKSPDAFKVSLPLRTNYLYGKIKKTLPELYAFTICLWLRSSASPGIGTPFSYAVPGQANEIVLIEWGNNPIELLINDKVAQLPLFVSDGKWHHICVTWTTRDGMWEAFQDGEKLGTGENLAPWHPIKPGGVLILGQEQDTVGGRFDATQAFVGELSQFNIWDRVLRAQEIINIANCSTNMPGNIIPWVDNNVDVFGGASKWPVETCEERLLDL", "length": 431, "header": "tr|G3MYU9-1|G3MYU9_BOVIN Isoform 1 of Neuronal pentraxin 2 OS=Bos taurus OX=9913 GN=NPTX2 PE=4 SV=2 CANONICAL=G3MYU9-1" }, "locus": { "chromosome": "25", "start_pos": 37512061, "end_pos": 37501338, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000066007.3", "url": "https://www.ensembl.org/id/ENSBTAT00000066007.3" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000054738.2", "url": "https://www.ensembl.org/id/ENSBTAP00000054738.2" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [ { "id": "bta:100336779", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?bta:100336779", "resource": "KEGG Pathway" } ], "orthologs": [ { "uniprot_canonical_ac": "F1RFK6-1", "protein_name": "Neuronal pentraxin 2", "gene_name": "NPTX2", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MLALLTAGVALAVAAGAQDGPAPGNRFVCTALPPEAARAGCPLAAMPMQGGALSPEEELRAAVLQLRETVVQQKETLGAQREAISELTAKLARCEGLAGGKAPGRAASGKDTMGDLPRDPGHVVEQLSRSLQTLKDRLENLEHQLRVNVSTAALPGDFREVLQRRLGELERQLLSKVAELEDEKSLLHNETSAHRQKTESALNALLQRVTELERGNSAFKSPDAFKVSLPLRTNYLYGKIKKTLPELYAFTICLWLRSSASPGIGTPFSYAVPGQANEIVLIEWGNNPIELLINDKVAQLPLFVSDGKWHHICVTWTTRDGMWEAFQDGEKLGTGENLAPWHPIKPGGVLILGQEQDTVGGRFDATQAFVGELSQFNIWDRVLRAQEIIGIANCSTNMAGNIIPWVDNNVDVFGGASKWPVETCEERLLDL", "length": 431 }, "evidence": [ { "id": "G3MYU9", "url": "https://omabrowser.org/oma/group/G3MYU9/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "O70340-1", "protein_name": "Neuronal pentraxin-2", "gene_name": "Nptx2", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MLALLTVGVALAVAAGRAQDSPIPGSRFVCTALPPEAARAGCPLPAMPMQGGALSPEEELRAAVLQLRETVVQQKETLGAQREAIRELTGKLARCEGLAGGKARGTGKDTMGDLPRDPGHVVEQLSRSLQTLKDRLESLELQLRTNVSNAGLPSDFREVLQRRLGELERQLLRKVAELEDEKSLLHNETSAHRQKTESTLNALLQRVTELERGNSAFKSPDAFKVSLPLRTNYLYGKIKKTLPELYAFTICLWLRSSASPGIGTPFSYAVPGQANEIVLIEWGNNPIELLINDKVAQLPLFVSDGKWHHICITWTTRDGMWEAFQDGEKLGTGENLAPWHPIKPGGVLILGQEQDTVGGRFDATQAFVGELSQFNIWDRVLRAQEIINIANCSTNMPGNIIPWVDNNVDVFGGASKWPVETCEERLLDL", "length": 429 }, "evidence": [ { "id": "G3MYU9", "url": "https://omabrowser.org/oma/group/G3MYU9/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "P47972-1", "protein_name": "Neuronal pentraxin-2", "gene_name": "NPTX2", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MLALLAASVALAVAAGAQDSPAPGSRFVCTALPPEAVHAGCPLPAMPMQGGAQSPEEELRAAVLQLRETVVQQKETLGAQREAIRELTGKLARCEGLAGGKARGAGATGKDTMGDLPRDPGHVVEQLSRSLQTLKDRLESLEHQLRANVSNAGLPGDFREVLQQRLGELERQLLRKVAELEDEKSLLHNETSAHRQKTESTLNALLQRVTELERGNSAFKSPDAFKVSLPLRTNYLYGKIKKTLPELYAFTICLWLRSSASPGIGTPFSYAVPGQANEIVLIEWGNNPIELLINDKVAQLPLFVSDGKWHHICVTWTTRDGMWEAFQDGEKLGTGENLAPWHPIKPGGVLILGQEQDTVGGRFDATQAFVGELSQFNIWDRVLRAQEIVNIANCSTNMPGNIIPWVDNNVDVFGGASKWPVETCEERLLDL", "length": 431 }, "evidence": [ { "id": "G3MYU9", "url": "https://omabrowser.org/oma/group/G3MYU9/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "P97738-1", "protein_name": "Neuronal pentraxin-2", "gene_name": "Nptx2", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MLALLTAGVALAVAAGQAQDNPIPGSRFVCTALPPEAARAGCPLPAMPMQGGALSPEEELRAAVLHWRETVVQQKETLGAQREAIRELTSKLARCEGLAGGKARGTGATGKDTMGDLPRDPGHVVEQLSRSLQTLKDRLESLELQLHTNASNAGLPSDFREVLQRRLGELERQLLRKVAELEDEKSLLHNETSAHRQKTENTLNALLQRVTELERGNSAFKSPDAFKVSLPLRTNYLYGKIKKTLPELYAFTICLWLRSSASPGIGTPFSYAVPGQANEIVLIEWGNNPIELLINDKVAQLPLFVSDGKWHHICITWTTRDGMWEAFQDGEKLGTGENLAPWHPIKPGGVLILGQEQDTVGGRFDATQAFVGELSQFNIWDRVLRAQEIINIANCSTNMPGNIIPWVDNNVDVFGGASKWPVETCEERLLDL", "length": 432 }, "evidence": [ { "id": "G3MYU9", "url": "https://omabrowser.org/oma/group/G3MYU9/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" } ], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 2, "go_terms": [ { "name": "glutamatergic synapse", "id": "GO:0098978", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0098978", "evidence": [ { "database": "UniProtKB", "id": "G3MYU9", "url": "https://www.uniprot.org/uniprotkb/G3MYU9" } ], "pmid": "" }, { "name": "presynapse", "id": "GO:0098793", "url": 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"sequence": "MTSELDIFVGNTTLIDEDVYRLWLDGYSVSDAVALRVRSGILEQTGATAAVLQSDTMDHYRTFHMLERLLHAPPKLLHQLIFQIPPSRQALLIERYYAFDEAFVREVLGKKLSKGTKKDLDDISTKTGITLKSCRRQFDNFKRVFKVVEEMRGSLVDNIQQHFLLSDRLARDYAAIVFFANNRFETGKKKLQYLSFGDFAFCAELMIQNWTLGAVDSQVDDMDMDLDKEFLQDLKELKVLVADKDLLDLHKSLVCTALRGKLGVFSEMEANFKNLSRGLVNVAAKLTHNKDVRDLFVDLVEKFVEPCRSDHWPLNDVRLFLNQYSASVHSLDGFRPRYRHLDQGSGSPGPLRLEFR", "length": 356, "header": "tr|A0AAA9T1Q9-1|F6RM59_BOVIN Computationally mapped isoform of FGF1 intracellular binding protein OS=Bos taurus OX=9913 GN=FIBP PE=4 SV=1 CANONICAL=F6RM59-1" }, "locus": { "chromosome": "29", "start_pos": 44003454, "end_pos": 43996958, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000125569.1", "url": "https://www.ensembl.org/id/ENSBTAT00000125569.1" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000091663.1", "url": "https://www.ensembl.org/id/ENSBTAP00000091663.1" } ] } }, { "isoform_ac": "A0AAA9TVX8-1", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TVX8/entry", "sequence": { "sequence": "MDCSLAGSSVHGDSRVSDAVALRVRSGILEQTGATAAVLQSDTMDHYRTFHMLERLLHAPPKLLHQLIFQIPPSRQALLIERYYAFDEAFVREVLGKKLSKGTKKDLDDISTKTGITLKSCRRQFDNFKRVFKVVEEMRGSLVDNIQQHFLLSDRLARDYAAIVFFANNRFETGKKKLQYLSFGDFAFCAELMIQNWTLGAVDSQVDDMDMDLDKEFLQDLKELKVLVADKDLLDLHKSLVCTALRGKLGVFSEMEANFKNLSRGLVNVAAKLTHNKDVRDLFVDLVEKFVEPCRSDHWPLNDVRLFLNQYSASVHSLDGFRHQALWDRYMGTLRGCLLRLYHD", "length": 344, "header": "tr|A0AAA9TVX8-1|F6RM59_BOVIN Computationally mapped isoform of FGF1 intracellular binding protein OS=Bos taurus OX=9913 GN=FIBP PE=4 SV=1 CANONICAL=F6RM59-1" }, "locus": { "chromosome": "29", "start_pos": 44005167, "end_pos": 43999558, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000099999.1", "url": "https://www.ensembl.org/id/ENSBTAT00000099999.1" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000102776.1", "url": "https://www.ensembl.org/id/ENSBTAP00000102776.1" } ] } }, { "isoform_ac": "F6RM59-1", "url": "https://www.uniprot.org/uniprotkb/F6RM59/entry", "sequence": { "sequence": "MTSELDIFVGNTTLIDEDVYRLWLDGYSVSDAVALRVRSGILEQTGATAAVLQSDTMDHYRTFHMLERLLHAPPKLLHQLIFQIPPSRQALLIERYYAFDEAFVREVLGKKLSKGTKKDLDDISTKTGITLKSCRRQFDNFKRVFKVVEEMRGSLVDNIQQHFLLSDRLARDYAAIVFFANNRFETGKKKLQYLSFGDFAFCAELMIQNWTLGAVGEAPTDPDSQVDDMDMDLDKEFLQDLKELKVLVADKDLLDLHKSLVCTALRGKLGVFSEMEANFKNLSRGLVNVAAKLTHNKDVRDLFVDLVEKFVEPCRSDHWPLNDVRLFLNQYSASVHSLDGFRHQALWDRYMGTLRGCLLRLYHD", "length": 364, "header": "tr|F6RM59-1|F6RM59_BOVIN Isoform 1 of FGF1 intracellular binding protein OS=Bos taurus OX=9913 GN=FIBP PE=4 SV=1 CANONICAL=F6RM59-1" }, "locus": { "chromosome": "29", "start_pos": 44003454, "end_pos": 43999558, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000027685.6", "url": "https://www.ensembl.org/id/ENSBTAT00000027685.6" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000027685.5", "url": "https://www.ensembl.org/id/ENSBTAP00000027685.5" } ] } } ], 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"table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ], "tool_support": { "graph_view": "yes" } }, { "uniprot_canonical_ac": "G3N0K6-1", "uniprot_ac": "G3N0K6", "uniprot_id": "G3N0K6_BOVIN", "mass": { "chemical_mass": 71266.0, "monoisotopic_mass": 71266.0 }, "refseq": { "ac": "NP_001164003", "name": "nucleolar protein 4 isoform 1", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001164003" }, "gene_names": [ { "name": "NOL4", "type": "recommended", "evidence": [ { "id": "G3N0K6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3N0K6" } ] }, { "name": "NOL4", "type": "synonym", "evidence": [ { "id": "NP_001164003", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001164003" } ] } ], "protein_names": [ { "name": "Nucleolar protein 4", "type": "synonym", "evidence": [ { "id": "G3N0K6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3N0K6/entry#names_and_taxonomy" } ] }, { "name": "nucleolar protein 4 isoform 1", "type": "synonym", "evidence": [ { "id": "NP_001164003", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001164003" } ] } ], "function": [], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Bos taurus", "taxid": 9913, "evidence": [ { "database": "UniProtKB", "id": "G3N0K6", "url": "https://www.uniprot.org/uniprotkb/G3N0K6" } ], "common_name": "Bovine", "glygen_name": "Bovine", "reference_species": "Bos taurus [9913]" } ], "gene": [ { "name": "NOL4", "url": "https://www.uniprot.org/uniprotkb/G3N0K6", "locus": { "chromosome": "24", "start_pos": 23337742, "end_pos": 22850081, "strand": "-", "evidence": [ { "database": "Ensembl Gene", "id": "ENSBTAG00000010299", "url": "https://www.ensembl.org/id/ENSBTAG00000010299" } ] } } ], "crossref": [ { "id": "G3N0K6", "url": "https://alphafold.ebi.ac.uk/entry/G3N0K6", "database": "AlphaFoldDB", "categories": [] }, { "id": "ENSBTAG00000010299", "url": "https://bgee.org/?page=gene&gene_id=ENSBTAG00000010299", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "536981", "url": "https://www.ncbi.nlm.nih.gov/gene/536981", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR039788", "url": "https://www.ebi.ac.uk/interpro/entry/IPR039788", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR056549", "url": "https://www.ebi.ac.uk/interpro/entry/IPR056549", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "XSRPIPS", "url": "https://omabrowser.org/oma/group/XSRPIPS/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "G3N0K6", "url": "https://www.orthodb.org/?gene=G3N0K6", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR12449", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR12449", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR12449:SF17", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR12449:SF17", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF23079", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF23079", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "NP_001164003", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001164003", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0AAA9SCA3", "url": "https://www.uniprot.org/uniprotkb/A0AAA9SCA3", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0AAA9SCA3-1", "url": "https://www.uniprot.org/uniprotkb/A0AAA9SCA3-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0AAA9T315", "url": "https://www.uniprot.org/uniprotkb/A0AAA9T315", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0AAA9T315-1", "url": "https://www.uniprot.org/uniprotkb/A0AAA9T315-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0AAA9TPQ5", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TPQ5", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0AAA9TPQ5-1", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TPQ5-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "G3N0K6", "url": "https://www.uniprot.org/uniprotkb/G3N0K6", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "G3N0K6-1", "url": "https://www.uniprot.org/uniprotkb/G3N0K6-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MESERDVYRQFQDWCLRTYGDSGKTKTVTRKKYERIVQLLNGCESSSTDNAKFKFWVKSKGFQLGQPDEVRGGGGGAKQVLYVPVKTTDGVGVDEKLSLRRVAVVEDFFDIIYSMHVETGPNGEQIRKHAGQKRTYKAISESYAFLPREAVTRFLMSCSECQKRMHLNPDGTDHKDNGKPPTLVTSMIDYNMPITMAYMKHMKLQLLNSQQEEDESSIESDEFDMSDSTRMSAVNSDLSSNLEERMQSPQALHGQQDDDSATESFNGNETLGHSSIASGGTHSREMGDSNCDGKTGLEQDEQPLNLSDSPLSAQLTSEYRIDDHSTNGKNKYKNLLISDLKMEREARENGSKSPAHSYSSYDSGKNESVDRGAEDLSLNRGDEDEDDHDDHEDSEKANETDGVEAERLKAFNMFVRLFVDENLDRMVPISKQPKEKIQAIIDSCRRQFPEYQERARKRIRTYLKSCRRMKRSGFEMSRPIPSHLTSAVAESILASACESESRNAAKRMRLDRQQDESAPTDKQCKPEAAQGTYSTSAVSGSQEVLYINGNGTYSYHSYRGLGGGLLNLNDASSSGPTDLSMKRQLATSSGSSSSSSSRPQLSPTEINAVRQLVAGYRESAAFLLRSADELENLILQQN", "length": 638, "header": "tr|G3N0K6-1|G3N0K6_BOVIN Isoform 1 of Nucleolar protein 4 OS=Bos taurus OX=9913 GN=NOL4 PE=4 SV=1 CANONICAL=G3N0K6-1" }, "isoforms": [ { "isoform_ac": "A0AAA9SCA3-1", "url": "https://www.uniprot.org/uniprotkb/A0AAA9SCA3/entry", "sequence": { "sequence": "MESERDVYRQFQDWCLRTYGDSGKTKTVTRKKYERIVQLLNGCESSSTDNAKFKFWVKSKGFQLGQPDEVRGGGGGAKQVLYVPVKTTDGVGVDEKLSLRRVAVVEDFFDIIYSMHVETGPNGEQIRKHAGQKRTYKAISESYAFLPREAVTRFLMSCSECQKRMHLNPDGTDHKDNGKPPTLVTSMIDYNMPITMAYMKHMKLQLLNSQQEEDESSIESDEFDMSDSTRMSAVNSDLSSNLEERMQSPQALHGQQDDDSATESFNGNETLGHSSIASGGTHSREMGDSNCDGKTGLEQDEQPLNLSDSPLSAQLTSEYRIDDHSTNGKNKYKNLLISDLKMEREARENGSKSPAHSYSSYDSGKNESVDRGAEDLSLNRGDEDEDDHDDHEDSEKANETDGVEAERLKAFNDESAPTDKQCKPEAAQGTYSTSAVSGSQEVLYINGNGTYSYHSYRGLGGGLLNLNDASSSGPTDLSMKRQLATSSGSSSSSSSRPQLSPTEINAVRQLVAGYRESAAFLLRSADELENLILQQN", "length": 536, "header": "tr|A0AAA9SCA3-1|G3N0K6_BOVIN Computationally mapped isoform of Nucleolar protein 4 OS=Bos taurus OX=9913 GN=NOL4 PE=4 SV=1 CANONICAL=G3N0K6-1" }, "locus": { "chromosome": "24", "start_pos": 23336047, "end_pos": 22850144, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000117388.1", "url": "https://www.ensembl.org/id/ENSBTAT00000117388.1" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000079864.1", "url": "https://www.ensembl.org/id/ENSBTAP00000079864.1" } ] } }, { "isoform_ac": "A0AAA9T315-1", "url": "https://www.uniprot.org/uniprotkb/A0AAA9T315/entry", "sequence": { "sequence": "MADFASLRAIHSWCCSYPLLQCQAGINLDAHQLENGQNDGVGVDEKLSLRRVAVVEDFFDIIYSMHVETGPNGEQIRKHAGQKRTYKAISESYAFLPREAVTRFLMSCSECQKRMHLNPDGTDHKDNGKPPTLVTSMIDYNMPITMAYMKHMKLQLLNSQQEEDESSIESDEFDMSDSTRMSAVNSDLSSNLEERMQSPQALHGQQDDDSATESFNGNETLGHSSIASGGTHSREMGDSNCDGKTGLEQDEQPLNLSDSPLSAQLTSEYRIDDHSTNGKNKYKNLLISDLKMEREARENGSKSPAHSYSSYDSGKNESVDRGAEDLSLNRGDEDEDDHDDHEDSEKANETDGVEAERLKAFNMFVRLFVDENLDRMVPISKQPKEKIQAIIDSCRRQFPEYQERARKRIRTYLKSCRRMKRSGFEMSRPIPSHLTSAVAESILASACESESRNAAKRMRLDRQQDESAPTDKQCKPEAAQGTYSTSAVSGSQEVLYINGNGTYSYHSYRGLGGGLLNLNDASSSGPTDLSMKRQLATSSGSSSSSSSRPQLSPTEINAVRQLVAGYRESAAFLLRSADELENLILQQN", "length": 588, "header": "tr|A0AAA9T315-1|G3N0K6_BOVIN Computationally mapped isoform of Nucleolar protein 4 OS=Bos taurus OX=9913 GN=NOL4 PE=4 SV=1 CANONICAL=G3N0K6-1" }, "locus": { "chromosome": "24", "start_pos": 23336047, "end_pos": 22853008, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000105716.1", "url": "https://www.ensembl.org/id/ENSBTAT00000105716.1" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000092138.1", "url": "https://www.ensembl.org/id/ENSBTAP00000092138.1" } ] } }, { "isoform_ac": "A0AAA9TPQ5-1", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TPQ5/entry", "sequence": { "sequence": "MESERDVYRQFQDWCLRTYGDSGKTKTVTRKKYERIVQLLNGCESSSTDNAKFKFWVKSKGFQLGQPDEVRGGGGGAKQVLYVPVKTTDGVGVDEKLSLRRVAVVEDFFDIIYSMHVETGPNGEQIRKHAGQKRTYKAISESYAFLPREAVTRFLMSCSECQKRMHLNPDGTDHKDNGKPPTLVTSMIDYNMPITMAYMKHMKLQLLNSQQEEDESSIESDEFDMSDSTRMSAVNSDLSSNLEERMQSPQALHGQQDDDSATESFNGNETLGHSSIASGGTHSREMGDSNCDGKTGLEQDEQPLNLSDSPLSAQLTSEYRIDDHSTNGKNKYKNLLISDLKMEREARENGSKSPAHSYSSYDSGKNESVDRGAEDLSLNRGDEDEDDHDDHEDSEKANETDGVEAERLKAFNMFVRLFVDENLDRMVPISKQPKEKIQAIIDSCRRQFPEYQERARKRIRTYLKSCRRMKRSGFEMSRPIPSHLTSAVAESILASACESESRNAAKRMRLDRQQDESAPTDKQCKPEAAQGTYSTSAVSGSQEVLYINGNGTYSYHSYRGLGGGLLNLNDASSSGI", "length": 576, "header": "tr|A0AAA9TPQ5-1|G3N0K6_BOVIN Computationally mapped isoform of Nucleolar protein 4 OS=Bos taurus OX=9913 GN=NOL4 PE=4 SV=1 CANONICAL=G3N0K6-1" }, "locus": { "chromosome": "24", "start_pos": 23267849, "end_pos": 22850144, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000118717.1", "url": "https://www.ensembl.org/id/ENSBTAT00000118717.1" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000099003.1", "url": "https://www.ensembl.org/id/ENSBTAP00000099003.1" } ] } }, { "isoform_ac": "G3N0K6-1", "url": "https://www.uniprot.org/uniprotkb/G3N0K6/entry", "sequence": { "sequence": "MESERDVYRQFQDWCLRTYGDSGKTKTVTRKKYERIVQLLNGCESSSTDNAKFKFWVKSKGFQLGQPDEVRGGGGGAKQVLYVPVKTTDGVGVDEKLSLRRVAVVEDFFDIIYSMHVETGPNGEQIRKHAGQKRTYKAISESYAFLPREAVTRFLMSCSECQKRMHLNPDGTDHKDNGKPPTLVTSMIDYNMPITMAYMKHMKLQLLNSQQEEDESSIESDEFDMSDSTRMSAVNSDLSSNLEERMQSPQALHGQQDDDSATESFNGNETLGHSSIASGGTHSREMGDSNCDGKTGLEQDEQPLNLSDSPLSAQLTSEYRIDDHSTNGKNKYKNLLISDLKMEREARENGSKSPAHSYSSYDSGKNESVDRGAEDLSLNRGDEDEDDHDDHEDSEKANETDGVEAERLKAFNMFVRLFVDENLDRMVPISKQPKEKIQAIIDSCRRQFPEYQERARKRIRTYLKSCRRMKRSGFEMSRPIPSHLTSAVAESILASACESESRNAAKRMRLDRQQDESAPTDKQCKPEAAQGTYSTSAVSGSQEVLYINGNGTYSYHSYRGLGGGLLNLNDASSSGPTDLSMKRQLATSSGSSSSSSSRPQLSPTEINAVRQLVAGYRESAAFLLRSADELENLILQQN", "length": 638, "header": "tr|G3N0K6-1|G3N0K6_BOVIN Isoform 1 of Nucleolar protein 4 OS=Bos taurus OX=9913 GN=NOL4 PE=4 SV=1 CANONICAL=G3N0K6-1" }, "locus": { "chromosome": "24", "start_pos": 23336047, "end_pos": 22850144, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000064561.2", "url": "https://www.ensembl.org/id/ENSBTAT00000064561.2" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000055369.1", "url": "https://www.ensembl.org/id/ENSBTAP00000055369.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [], "orthologs": [ { "uniprot_canonical_ac": "A0A8V0XMV7-1", "protein_name": "Nucleolar protein 4 like", "gene_name": "NOL4", "tax_id": 9031, "organism": "Gallus gallus", "sequence": { "sequence": "MESGDRDMYRQFQDWCLRTYGDSGKTKTVTRKKYERIVQLLNGSESSSTDNAKFKFWVKSKGFQLGDSDEVSGGAGGGKQVLYVPVKTTDGVGVDEKLSLRRVAVVEDFFDIIYSMHVETGPNGEQIRKHAGQKRTYKAISETYAFLPREAVTRFLMSCSECQKRMHLNPDGADHKDNGKPPTLVTSMIDYNMPITMAYMKHMKLQLLNSQQDEDESSIESDEFDMSDSTRMSAVNSDLSSNLEERMQSPQNLQSQQDDDSAAESFNGNETVGHSSNASGGTHCREMAETNSNGKTNLEQDEQPLNLSDSPLSAQLTSEYRLDDHSSNGKNKYKTLLISDLKMEREARENGSKSPAHSYSSYDSGKNESVDRGAEDLSLNRGDEDEDDHDEQEDPEKVNESDGVEAERLKAFNMFVRLFVDENLDRMVPISKQPKEKIQAIIDSCRRQFPEYQERARKRIRTYLKSCRRMKRSGFEMSRPIPSHLTSAVAESILASACESESRNAAKRMRLDRQQDEATPADKQYKQEPAQVTYSTSAVSSTQEVLYINGNGTYSYHSYRGLGGGLLNLNDASSSDLQPTSTTATTQHCIPGSTNVQSPSNSGPTDLSMKRQLASSSGSSSSTSSRPQLSPTEINAVRQLVAGYRESAAFLLRSADELENLILQQN", "length": 666 }, "evidence": [ { "id": "G3N0K6", "url": "https://omabrowser.org/oma/group/G3N0K6/", "database": "OMA" } ], "glygen_name": "Chicken", "common_name": "Chicken" }, { "uniprot_canonical_ac": "D4A3P4-1", "protein_name": "Nucleolar protein 4", "gene_name": "Nol4", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MESERDMYRQFQDWCLRTYGDSGKTKTVTRKKYERIVQLLNGSESSSTDNAKFKFWVKSKGFQLGQPDEVRGGGGGAKQVLFVRVKTTDGVGVDEKLSLRRVAVVEDFFDIIYSMHVETGPNGEQIRKHAGQKRTYKAISESYAFLPREAVTRFLMSCSECQKRMHLNPDGTDHKDNGKPPTLVTSMIDYNMPITMAYMKHMKLQLLNSQQDEDESSIESDEFDMSDSTRMSAVNSDLSSNLEERVQSPQTAQGQQDDDSAAESSNGNETLGHSSVASGGAHGREPGDSSSDGKTGLEQEEQPLNLSDSPRSAQLTSEYRVEDQGSNGKNKYKNLLISDLKMEREARENGSKSPAHSYSSYDSGKNEGVDRGAEDLSLSRGDEDEDEHDEHEDSEKVNESDGVEAERLKAFNMFVRLFVDENLDRMVPISKQPKEKIQAIIDSCRRQFPEYQERARKRIRTYLKSCRRMKRSGFEMSRPIPSHLTSAVAESILASACESESRNAAKRMRLDKTQDEATPADKQCKPEAAQATYSTSTVPGSQEVLYINGNGTYSYHSYRGLGGGLLNLNDTSSSGPTDLSMKRQLAPGSGSSSSSNPRPQLSPTEINAVRQLVAGYRESAAFLLRSADELENLILQQN", "length": 638 }, "evidence": [ { "id": "G3N0K6", "url": "https://omabrowser.org/oma/group/G3N0K6/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "F1SAK1-1", "protein_name": "Nucleolar protein 4", "gene_name": "NOL4", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MESERDMYRQFQDWCLRTYGDSGKTKTVTRKKYERIVQLLNGCESSSTDNAKFKFWVKSKGFQLGQPDEVRGGSGGAKQVLYVPVKTTDGIGVDEKLSLRRVAVVEDFFDIIYSMHVETGPNGEQIRKHAGQKRTYKAISESYAFLPREAVTRFLMSCSECQKRMHLNPDGTDHKDNGKPPTLVTSMIDYNMPITMAYMKHMKLQLLNSQQDEDESSIESDEFDMSDSTRMSAVNSDLSSNLEERMQSPQALHSQQDDDSAAESFNGNETLGHSSVASGGTQSREMGDSNGDGKTGLEQDEQPLNLSDSPLSAQLTSEYRIDDPNSNGKNKYKNLLISDLKMEREARENGSKSPAHSYSSYDSGKNESVDRGAEDLSLNRGDEDEDDHDDHDDSEKVNETDGVEAERLKAFNMFVRLFVDENLDRMVPISKQPKEKIQAIIDSCRRQFPEYQERARKRIRTYLKSCRRMKRSGFEMSRPIPSHLTSAVAESILASACESESRNAAKRMRLDRQQDESAPGDKQCKPEAAQGTYSTSAVSGSQEVLYINGNGTYSYHSYRGLGGGLLNLNDASSSGPTDLSMKRQLATSSGSSSSSSSRPQLSPTEINAVRQLVAGYRESAAFLLRSADELENLILQQN", "length": 638 }, "evidence": [ { "id": "G3N0K6", "url": "https://omabrowser.org/oma/group/G3N0K6/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "O94818-1", "protein_name": "Nucleolar protein 4", "gene_name": "NOL4", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MESERDMYRQFQDWCLRTYGDSGKTKTVTRKKYERIVQLLNGSESSSTDNAKFKFWVKSKGFQLGQPDEVRGGGGGAKQVLYVPVKTTDGVGVDEKLSLRRVAVVEDFFDIIYSMHVETGPNGEQIRKHAGQKRTYKAISESYAFLPREAVTRFLMSCSECQKRMHLNPDGTDHKDNGKPPTLVTSMIDYNMPITMAYMKHMKLQLLNSQQDEDESSIESDEFDMSDSTRMSAVNSDLSSNLEERMQSPQNLHGQQDDDSAAESFNGNETLGHSSIASGGTHSREMGDSNSDGKTGLEQDEQPLNLSDSPLSAQLTSEYRIDDHNSNGKNKYKNLLISDLKMEREARENGSKSPAHSYSSYDSGKNESVDRGAEDLSLNRGDEDEDDHEDHDDSEKVNETDGVEAERLKAFNMFVRLFVDENLDRMVPISKQPKEKIQAIIDSCRRQFPEYQERARKRIRTYLKSCRRMKRSGFEMSRPIPSHLTSAVAESILASACESESRNAAKRMRLERQQDESAPADKQCKPEATQATYSTSAVPGSQDVLYINGNGTYSYHSYRGLGGGLLNLNDASSSGPTDLSMKRQLATSSGSSSSSNSRPQLSPTEINAVRQLVAGYRESAAFLLRSADELENLILQQN", "length": 638 }, "evidence": [ { "id": "G3N0K6", "url": "https://omabrowser.org/oma/group/G3N0K6/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "P60954-1", "protein_name": "Nucleolar protein 4", "gene_name": "Nol4", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MESERDMYRQFQDWCLRTYGDSGKTKTVTRKKYERIVQLLNGSESSSTDNAKFKFWVKSKGFQLGQPDEVRGGGGGAKQVLFVRVKTTDGVGVDEKLSLRRVAVVEDFFDIIYSMHVETGPNGEQIRKHAGQKRTYKAISESYAFLPREAVTRFLMSCSECQKRMHLNPDGTDHKDNGKPPTLVTSMIDYNMPITMAYMKHMKLQLLNSQQDEDESSIESDEFDMSDSTRMSAVNSDLSSNLEERMQSPQTVHGQQDDDSAAESSNGNETLGHSSAASGGAHGREPEDSSSDGKTGLEQEEQPLNLSDSPSSAQLTSEFRIDDQGSDGKNKYKNLLISDLKMEREARENGSKSPAHSYSSYDSGKNESVDRGAEDLSLNRGDEDEDEHDEHEDSEKVNETDGVEAERLKAFNSRPIPSHLTSAVAESILASACESESRNAAKRMRLDKAQDEAAPADKQCKPEAAQATYSTATVPGSQEDPQI", "length": 483 }, "evidence": [ { "id": "G3N0K6", "url": "https://omabrowser.org/oma/group/G3N0K6/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" } ], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 1, "go_terms": [ { "name": "nucleoplasm", "id": "GO:0005654", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005654", "evidence": [ { "database": "UniProtKB", "id": "G3N0K6", "url": "https://www.uniprot.org/uniprotkb/G3N0K6" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 268, "end_pos": 270, "annotation": "n_glycosylation_sequon" }, { "start_pos": 305, "end_pos": 307, "annotation": "n_glycosylation_sequon" }, { "start_pos": 349, "end_pos": 351, "annotation": "n_glycosylation_sequon" }, { "start_pos": 366, "end_pos": 368, "annotation": "n_glycosylation_sequon" }, { "start_pos": 398, "end_pos": 400, "annotation": "n_glycosylation_sequon" }, { "start_pos": 550, "end_pos": 552, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [ { "pdb_id": "AF-G3N0K6-F1", "pdb_chain": "global", "start_pos": 1, "end_pos": 638, "overlap": "1.0", "method": "AlphaFold", "type": "alphafold", "resolution": -1.0, "url": "https://data.glygen.org/ln2downloads/pdb/current/AF-G3N0K6-F1.pdb", "url_external": "https://alphafold.ebi.ac.uk/entry/G3N0K6" } ], "lectin_list": [], "domain_list": [ 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}, { "id": "PTHR16797:SF4", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR16797:SF4", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "A0AAA9SDX5", "url": "https://www.uniprot.org/uniprotkb/A0AAA9SDX5", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0AAA9SDX5-1", "url": "https://www.uniprot.org/uniprotkb/A0AAA9SDX5-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "G3X7W1", "url": "https://www.uniprot.org/uniprotkb/G3X7W1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "G3X7W1-1", "url": "https://www.uniprot.org/uniprotkb/G3X7W1-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MAASAAGLGGGGAGPGPEPGDFLARYRQVSNKLKKRFLRKPNVAEAGEQFAQLGRELRAQECLPYAAWCQLAVARCQQALFHGSGEALALTEAARLFLRQERDARQRLACPAAAGEALQAAAAALGAAVRLHLELGQPAAAAALCLELAAALRDLGQPAAAAGHFQRAAQLQLPQLPLAALQALGHAASCQLLARDYSGALALFTHMQRLARELGGIPSQPPPPQPAAPGPPLPPGAGPPAAAAPAALGAFADVLVRCEVSRVLLLLLLQPPPAKLLPEHAHTLEKYAWEAFDGHGQDSSGPLPEELFLLLQSLVMATHEKDTEAVKLLQVEMWPLLSAEQNHLLHLVLQETVSPSGQGI", "length": 360, "header": "tr|G3X7W1-1|G3X7W1_BOVIN Isoform 1 of Factor VIII intron 22 protein OS=Bos taurus OX=9913 GN=F8A1 PE=4 SV=3 CANONICAL=G3X7W1-1" }, "isoforms": [ { "isoform_ac": "A0AAA9SDX5-1", "url": "https://www.uniprot.org/uniprotkb/A0AAA9SDX5/entry", "sequence": { "sequence": "AASAAGLGGGGAGPGPEPGDFLARYRQVSNKLKKRFLRKPNVAEAGEQFAQLGRELRAQECLPYAAWCQLAVARCQQALFHGSGEALALTEAARLFLRQERDARQRLACPAAAGEALQAAAAALGAAVRLHLELGQPAAAAALCLELAAALRDLGQPAAAAGHFQRAAQLQLPQLPLAALQALGHAASCQLLARDYSGALALFTHMQRLARELGGIPSQPPPPQPAAPGPPLPPGAGPPAAAAPAALGAFADVLVRCEVSRVLLLLLLQPPPAKLLPEHAHTLEKYAWEAFDGHGQDSSGPLPEELFLLLQSLVMATHEKDTEAVKLLQVEMWPLLSAEQNHLLHLVLQETVSPSGQGI", "length": 359, "header": "tr|A0AAA9SDX5-1|G3X7W1_BOVIN Computationally mapped isoform of Factor VIII intron 22 protein OS=Bos taurus OX=9913 GN=F8A1 PE=4 SV=1 CANONICAL=G3X7W1-1" }, "locus": { "chromosome": "X", "start_pos": 36138358, "end_pos": 36137282, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000103143.1", "url": "https://www.ensembl.org/id/ENSBTAT00000103143.1" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000082014.1", "url": "https://www.ensembl.org/id/ENSBTAP00000082014.1" } ] } }, { "isoform_ac": "G3X7W1-1", "url": "https://www.uniprot.org/uniprotkb/G3X7W1/entry", "sequence": { "sequence": "MAASAAGLGGGGAGPGPEPGDFLARYRQVSNKLKKRFLRKPNVAEAGEQFAQLGRELRAQECLPYAAWCQLAVARCQQALFHGSGEALALTEAARLFLRQERDARQRLACPAAAGEALQAAAAALGAAVRLHLELGQPAAAAALCLELAAALRDLGQPAAAAGHFQRAAQLQLPQLPLAALQALGHAASCQLLARDYSGALALFTHMQRLARELGGIPSQPPPPQPAAPGPPLPPGAGPPAAAAPAALGAFADVLVRCEVSRVLLLLLLQPPPAKLLPEHAHTLEKYAWEAFDGHGQDSSGPLPEELFLLLQSLVMATHEKDTEAVKLLQVEMWPLLSAEQNHLLHLVLQETVSPSGQGI", "length": 360, "header": "tr|G3X7W1-1|G3X7W1_BOVIN Isoform 1 of Factor VIII intron 22 protein OS=Bos taurus OX=9913 GN=F8A1 PE=4 SV=3 CANONICAL=G3X7W1-1" }, "locus": { "chromosome": "X", "start_pos": 36133761, "end_pos": 36133598, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000047113.5", "url": "https://www.ensembl.org/id/ENSBTAT00000047113.5" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000044343.5", "url": "https://www.ensembl.org/id/ENSBTAP00000044343.5" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [], "orthologs": [], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 1, "go_terms": [ { "name": "early endosome", "id": "GO:0005769", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005769", "evidence": [ { "database": "UniProtKB", "id": "G3X7W1", "url": "https://www.uniprot.org/uniprotkb/G3X7W1" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 1, "go_terms": [ { "name": "vesicle cytoskeletal trafficking", "id": "GO:0099518", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0099518", "evidence": [ { "database": "UniProtKB", "id": "G3X7W1", "url": "https://www.uniprot.org/uniprotkb/G3X7W1" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [ { "pdb_id": "AF-G3X7W1-F1", "pdb_chain": "global", "start_pos": 1, "end_pos": 360, "overlap": "1.0", "method": "AlphaFold", "type": "alphafold", "resolution": -1.0, "url": "https://data.glygen.org/ln2downloads/pdb/current/AF-G3X7W1-F1.pdb", "url_external": "https://alphafold.ebi.ac.uk/entry/G3X7W1" } ], "lectin_list": [], "domain_list": [], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ], "tool_support": { "graph_view": "yes" } }, { "uniprot_canonical_ac": "G3X7D8-1", "uniprot_ac": "G3X7D8", "uniprot_id": "G3X7D8_BOVIN", "mass": { "chemical_mass": 34143.0, "monoisotopic_mass": 34143.0 }, "refseq": {}, "gene_names": [ { "name": "MRRF", "type": "recommended", "evidence": [ { "id": "G3X7D8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3X7D8" } ] } ], "protein_names": [ { "name": "Ribosome-recycling factor, mitochondrial", "type": "recommended", "evidence": [ { "id": "G3X7D8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3X7D8/entry#names_and_taxonomy" } ] }, { "name": "Ribosome-releasing factor, mitochondrial", "type": "synonym", "evidence": [ { "id": "G3X7D8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3X7D8/entry#names_and_taxonomy" } ] } ], "function": [ { "annotation": "Responsible for the disassembly of ribosomes from messenger RNA at the termination of mitochondrial protein biosynthesis. Acts in collaboration with GFM2. Promotes mitochondrial ribosome recycling by dissolution of intersubunit contacts.", "evidence": [ { "database": "UniProtKB", "id": "A0AAA9TUT6", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TUT6#function" }, { "database": "UniProtKB", "id": "ARBA00055779", "url": "https://www.uniprot.org/uniprotkb/ARBA00055779#function" }, { "database": "UniProtKB", "id": "A0AAA9ST14", "url": "https://www.uniprot.org/uniprotkb/A0AAA9ST14#function" }, { "database": "UniProtKB", "id": "G3X7D8", "url": "https://www.uniprot.org/uniprotkb/G3X7D8#function" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Bos taurus", "taxid": 9913, "evidence": [ { "database": "UniProtKB", "id": "G3X7D8", "url": "https://www.uniprot.org/uniprotkb/G3X7D8" } ], "common_name": "Bovine", "glygen_name": "Bovine", "reference_species": "Bos taurus [9913]" } ], "gene": [ { "name": "MRRF", "url": "https://www.uniprot.org/uniprotkb/G3X7D8", "locus": { "chromosome": "11", "start_pos": 93206674, "end_pos": 93141140, "strand": "-", "evidence": [ { "database": "Ensembl Gene", "id": "ENSBTAG00000018426", "url": "https://www.ensembl.org/id/ENSBTAG00000018426" } ] } } ], "crossref": [ { "id": "G3X7D8", "url": "https://alphafold.ebi.ac.uk/entry/G3X7D8", "database": "AlphaFoldDB", "categories": [] }, { "id": "ENSBTAG00000018426", "url": "https://bgee.org/?page=gene&gene_id=ENSBTAG00000018426", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "IPR002661", "url": "https://www.ebi.ac.uk/interpro/entry/IPR002661", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR023584", "url": "https://www.ebi.ac.uk/interpro/entry/IPR023584", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR036191", "url": "https://www.ebi.ac.uk/interpro/entry/IPR036191", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "FNPMNNG", "url": "https://omabrowser.org/oma/group/FNPMNNG/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "G3X7D8", "url": "https://www.orthodb.org/?gene=G3X7D8", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR20982", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR20982", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR20982:SF10", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR20982:SF10", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF01765", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF01765", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "R-BTA-5419276", "url": "https://www.reactome.org/PathwayBrowser/#R-BTA-5419276", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "A0AAA9SF19", "url": "https://www.uniprot.org/uniprotkb/A0AAA9SF19", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0AAA9SF19-1", "url": "https://www.uniprot.org/uniprotkb/A0AAA9SF19-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0AAA9SJU2", "url": "https://www.uniprot.org/uniprotkb/A0AAA9SJU2", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0AAA9SJU2-1", "url": "https://www.uniprot.org/uniprotkb/A0AAA9SJU2-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0AAA9ST14", "url": "https://www.uniprot.org/uniprotkb/A0AAA9ST14", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0AAA9ST14-1", "url": "https://www.uniprot.org/uniprotkb/A0AAA9ST14-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0AAA9TUT6", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TUT6", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0AAA9TUT6-1", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TUT6-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "G3X7D8", "url": "https://www.uniprot.org/uniprotkb/G3X7D8", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "G3X7D8-1", "url": "https://www.uniprot.org/uniprotkb/G3X7D8-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MTHYARAAAPPRDVTTPAPPAPPPPPPWSRESFPNNPGASCGYSQGLSSVMALGLRCFRLVHPAFCNSLAALTRPVSEVTLQTVRGRQNDHGQCMAYAAVPVRHFATKKAKAKGKGQSQTRMNLNTALVEDIINLEEVDEEMKSVIEALKDNFNKTVNIRTSPGALDNITVVTADGKLPLNQISQISMKSPQLILVNMASFPECTAAAIKAIRESGMNLNPEVEGTLIRVPIPKVTREHREMLVKLAKQNTNKAKDSLRKVRTNAINKVKKSKDKASEDTIRLIEKQISQMADDTVAELDRHLAVKTKELLG", "length": 312, "header": "tr|G3X7D8-1|G3X7D8_BOVIN Isoform 1 of Ribosome-recycling factor, mitochondrial OS=Bos taurus OX=9913 GN=MRRF PE=3 SV=2 CANONICAL=G3X7D8-1" }, "isoforms": [ { "isoform_ac": "A0AAA9SF19-1", "url": "https://www.uniprot.org/uniprotkb/A0AAA9SF19/entry", "sequence": { "sequence": "MTHYARAAAPPRDVTTPAPPAPPPPPPWSRESFPNNPGASCGYSQGLSSVMALGLRCFRLVHPAFCNSLAALTRPVSEVTLQTVRGRQNDHGQCMAYAAVPVRHFATKKAKAKGKGQSQTRMNLNTALVEDIINLEEVDEEMKSVIEALKDNFNKTVNIRTSPGALDNITVVTADGKLPLNQISQISMKSPQLILVNMASFPECTAAAIKAIRESGMNLNPEVEGTLIRVPIPKVTREHREMLVKLAKQNTNKAKDSLRKVRTNAINKVKKSKDKASEDTIRLIEKQGRPPEG", "length": 293, "header": "tr|A0AAA9SF19-1|G3X7D8_BOVIN Computationally mapped isoform of Ribosome-recycling factor, mitochondrial OS=Bos taurus OX=9913 GN=MRRF PE=3 SV=1 CANONICAL=G3X7D8-1" }, "locus": { "chromosome": "11", "start_pos": 93206626, "end_pos": 93141363, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000094848.1", "url": "https://www.ensembl.org/id/ENSBTAT00000094848.1" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000082429.1", "url": "https://www.ensembl.org/id/ENSBTAP00000082429.1" } ] } }, { "isoform_ac": "A0AAA9SJU2-1", "url": "https://www.uniprot.org/uniprotkb/A0AAA9SJU2/entry", "sequence": { "sequence": "MALGLRCFRLVHPAFCNSLAALTRPVSEVTLQTVRGRQNDHGQCMAYAAVPVRHFATKKAKAKGKGQSQTRMNLNTALVEDIINLEEVDEEMKSVIEALKDNFNKTVNIRTSPGALDNITVVTADGKLPLNQISQISMKSPQLILVNMASFPECTAAAIKAIRESGMNLNPEVEGTLIRVPIPKSAKWPMTQWQSWTGIWP", "length": 201, "header": "tr|A0AAA9SJU2-1|G3X7D8_BOVIN Computationally mapped isoform of Ribosome-recycling factor, mitochondrial OS=Bos taurus OX=9913 GN=MRRF PE=3 SV=1 CANONICAL=G3X7D8-1" }, "locus": { "chromosome": "11", "start_pos": 93195864, "end_pos": 93147133, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000105548.2", "url": "https://www.ensembl.org/id/ENSBTAT00000105548.2" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000084095.1", "url": "https://www.ensembl.org/id/ENSBTAP00000084095.1" } ] } }, { "isoform_ac": "A0AAA9ST14-1", "url": "https://www.uniprot.org/uniprotkb/A0AAA9ST14/entry", "sequence": { "sequence": "MFIKCFCNSAHWVAPLTLMNSIVIHSGYSQGLSSVMALGLRCFRLVHPAFCNSLAALTRPVSEVTLQTVRGRQNDHGQCMAYAAVPVRHFATKKAKAKGKGQSQTRMNLNTALVEDIINLEEVDEEMKSVIEALKDNFNKTVNIRTSPGALDNITVVTADGKLPLNQISQISMKSPQLILVNMASFPECTAAAIKAIRESGMNLNPEVEGTLIRVPIPKVTREHREMLVKLAKQNTNKAKDSLRKVRTNAINKVKKSKDKASEDTIRLIEKQISQMADDTVAELDRHLAVKTKELLG", "length": 297, "header": "tr|A0AAA9ST14-1|G3X7D8_BOVIN Computationally mapped isoform of Ribosome-recycling factor, mitochondrial OS=Bos taurus OX=9913 GN=MRRF PE=3 SV=1 CANONICAL=G3X7D8-1" }, "locus": { "chromosome": "11", "start_pos": 93195887, "end_pos": 93142150, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000106185.2", "url": "https://www.ensembl.org/id/ENSBTAT00000106185.2" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000087256.1", "url": "https://www.ensembl.org/id/ENSBTAP00000087256.1" } ] } }, { "isoform_ac": "A0AAA9TUT6-1", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TUT6/entry", "sequence": { "sequence": "MALGLRCFRLVHPAFCNSLAALTRPVSEVTLQTVRGRQNDHGQCMAYAAVPVRHFATKKAKGALDNITVVTADGKLPLNQISQISMKSPQLILVNMASFPECTAAAIKAIRESGMNLNPEVEGTLIRVPIPKVTREHREMLVKLAKQNTNKAKDSLRKVRTNAINKVKKSKDKASEDTIRLIEKQISQMADDTVAELDRHLAVKTKELLG", "length": 210, "header": "tr|A0AAA9TUT6-1|G3X7D8_BOVIN Computationally mapped isoform of Ribosome-recycling factor, mitochondrial OS=Bos taurus OX=9913 GN=MRRF PE=3 SV=1 CANONICAL=G3X7D8-1" }, "locus": { "chromosome": "11", "start_pos": 93195887, "end_pos": 93147133, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000120122.2", "url": "https://www.ensembl.org/id/ENSBTAT00000120122.2" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000102390.1", "url": "https://www.ensembl.org/id/ENSBTAP00000102390.1" } ] } }, { "isoform_ac": "G3X7D8-1", "url": "https://www.uniprot.org/uniprotkb/G3X7D8/entry", "sequence": { "sequence": "MTHYARAAAPPRDVTTPAPPAPPPPPPWSRESFPNNPGASCGYSQGLSSVMALGLRCFRLVHPAFCNSLAALTRPVSEVTLQTVRGRQNDHGQCMAYAAVPVRHFATKKAKAKGKGQSQTRMNLNTALVEDIINLEEVDEEMKSVIEALKDNFNKTVNIRTSPGALDNITVVTADGKLPLNQISQISMKSPQLILVNMASFPECTAAAIKAIRESGMNLNPEVEGTLIRVPIPKVTREHREMLVKLAKQNTNKAKDSLRKVRTNAINKVKKSKDKASEDTIRLIEKQISQMADDTVAELDRHLAVKTKELLG", "length": 312, "header": "tr|G3X7D8-1|G3X7D8_BOVIN Isoform 1 of Ribosome-recycling factor, mitochondrial OS=Bos taurus OX=9913 GN=MRRF PE=3 SV=2 CANONICAL=G3X7D8-1" }, "locus": { "chromosome": "11", "start_pos": 93195887, "end_pos": 93141363, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000024516.7", "url": "https://www.ensembl.org/id/ENSBTAT00000024516.7" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000024516.5", "url": "https://www.ensembl.org/id/ENSBTAP00000024516.5" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [ { "id": "R-BTA-5419276", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-BTA-5419276", "resource": "Reactome", "description": "Mitochondrial translation termination" } ], "orthologs": [ { "uniprot_canonical_ac": "E1BQ58-1", "protein_name": "Ribosome-recycling factor, mitochondrial", "gene_name": "MRRF", "tax_id": 9031, "organism": "Gallus gallus", "sequence": { "sequence": "MAMALRCFRHLHSLLHCSSLAVVRQLPQPPARCTPLLLDGCRHCAHPLLLARPLATKKAKGKGQTQAKVNISAALVEDIINLEETNTDMQAVVEALKEDFNRNLNVRTSQGALDHIIVTTKDGKFPLNQLGQISQKSPQLIVVNMTSFPESTAAAMKAIRESGMNLNPEVDGTLIRVPVPKVTREHRESLAKLAKQSTNKSKEALRKVRSKSVNQVKKFKSKVSEDTIWLLEKQIQQMADSAAAEMDKLLAAKTKELLG", "length": 259 }, "evidence": [ { "id": "G3X7D8", "url": "https://omabrowser.org/oma/group/G3X7D8/", "database": "OMA" } ], "glygen_name": "Chicken", "common_name": "Chicken" }, { "uniprot_canonical_ac": "F1SLQ7-1", "protein_name": "Ribosome-recycling factor, mitochondrial", "gene_name": "MRRF", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MALGLRCFRLVHPAFCNSLAALTRPVSEVTLKTVSGSRNNHGQYMAYPAVPVCHFATKKAKAKGKGQSQTRMNLNTALVEDIISLEEVDEEMKSVIEALKDNFNKTVNIRTSPGSLDQITVVTADGKLALNQIGQISMKSPQLILVNMASFPECTAAAIKAIRESGMNLNPDVEGTLIRVPIPKVTREHREMLVKLAKQNTNKAKESLRKVRTNAMNKLKKSKDKASEDTLRLIEKQISQMADDTVAELERHLAVKTKELLG", "length": 262 }, "evidence": [ { "id": "G3X7D8", "url": "https://omabrowser.org/oma/group/G3X7D8/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "Q55G90-1", "protein_name": "Ribosome recycling factor domain-containing protein", "gene_name": "", "tax_id": 44689, "organism": "Dictyostelium discoideum", "sequence": { "sequence": "MIRGINRFSGCFVRSIGNNSNQQQQTYRGIISVAKTTTTSSFQRRSPFSIFNENSVMTLRAKKSGGGGGGKSNSKDDEVFTPWKQVDISSVSSQGDKTIEYVSRELGNIRFGRVGPELLERINVETPSGNLLLPHMAMITIKDSLTLNITLYDSSLLSNVERALTNSGLGLNPQTFDTTIRVSLPKPTQDLRQKLIKQVNTISEDAKVSIRRHRKDGMDILKRYKLTKDDEKTLEKNIQKITDDYIKSITKITETKLKEINSN", "length": 263 }, "evidence": [ { "id": "G3X7D8", "url": "https://omabrowser.org/oma/group/G3X7D8/", "database": "OMA" } ], "glygen_name": "Cellular slime mold", "common_name": "Social amoeba" }, { "uniprot_canonical_ac": "Q5RKI9-1", "protein_name": "Ribosome-recycling factor, mitochondrial", "gene_name": "Mrrf", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MALGIRCFRLLHPAFSSYLADLSRPVSEVPMKTVRGRQRDHIQYSAHPAVPVRQFATKKAKAKGKGQPQARVNINTALVEDIISLEEVDEDMKSVMEALKDNFNKTLNIRTAPGSLDHITVVTADGKLALNQIGQISMKSPQLILVNMASFPECTAAAIKAIRESGMNLNPEVEGTLIRVPIPKVTREHREMLVKLAKQNTNKAKENLRKVRTNAMNKLKKSKDKTSEDTIRLIEKQISQMADDTVAELDRHLAAKTKELLG", "length": 262 }, "evidence": [ { "id": "G3X7D8", "url": "https://omabrowser.org/oma/group/G3X7D8/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "Q96E11-1", "protein_name": "Ribosome-recycling factor, mitochondrial", "gene_name": "MRRF", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MALGLKCFRMVHPTFRNYLAASIRPVSEVTLKTVHERQHGHRQYMAYSAVPVRHFATKKAKAKGKGQSQTRVNINAALVEDIINLEEVNEEMKSVIEALKDNFNKTLNIRTSPGSLDKIAVVTADGKLALNQISQISMKSPQLILVNMASFPECTAAAIKAIRESGMNLNPEVEGTLIRVPIPQVTREHREMLVKLAKQNTNKAKDSLRKVRTNSMNKLKKSKDTVSEDTIRLIEKQISQMADDTVAELDRHLAVKTKELLG", "length": 262 }, "evidence": [ { "id": "G3X7D8", "url": "https://omabrowser.org/oma/group/G3X7D8/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "Q9D6S7-1", "protein_name": "Ribosome-recycling factor, mitochondrial", "gene_name": "Mrrf", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MASGIRCFRLLHPAFRSYHAALTRPVSEVSMKTVSGRQHGHRQYSAYPAVPVRHFATKKAKAKGKGQPQARVTVNRALVEDIISLEEVDEDMKSVVEALKDNFNKTLNIRTAPGSLDHITVVTADGKVALNQIGQISMKSPQVILVNMASFPECTAAAIKAIRESGMNLNPEVEGTLIRVPIPKVTREHREMLVKLAKQNTNKAKENLRKVRTNAMNKLKKSKDKTSEDTIRLIEKQISQMADDTVAELDQHLAAKTKELLG", "length": 262 }, "evidence": [ { "id": "G3X7D8", "url": "https://omabrowser.org/oma/group/G3X7D8/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q9M1X0-1", "protein_name": "Ribosome-recycling factor, chloroplastic", "gene_name": "RRF", "tax_id": 3702, "organism": "Arabidopsis thaliana", "sequence": { "sequence": "MAASFSSTAPTTPVLRFRANYSKPLLSLPDSCLRIISSAISPSTRLIACSFKTDKLPLGAGVNLSGGPVVKRSLQKRLVIRSATIEEIEAEKSAIETDVKSKMEKTIETLRTSFNSIRTGRSNAAMLDKIEVEYYGSPVSLKSIAQISTPDGSSLLLQPYDKSSLKAIEKAIVNSDLGVTPNNDGDVIRLSLPPLTSDRRKELSKVVAKQSEEGKVALRNIRRDALKSYDKLEKEKKLSEDNVKDLSSDLQKLIDVYMKKIEELYKQKEKELMKV", "length": 275 }, "evidence": [ { "id": "G3X7D8", "url": "https://omabrowser.org/oma/group/G3X7D8/", "database": "OMA" } ], "glygen_name": "Arabidopsis", "common_name": "Mouse-ear cress" }, { "uniprot_canonical_ac": "Q9VSW4-1", "protein_name": "Ribosome-recycling factor, mitochondrial", "gene_name": "mRRF1", "tax_id": 7227, "organism": "Drosophila melanogaster", "sequence": { "sequence": "MLRSALHLAALGVRQTRVSSSSPKLPLILQNNLENTKYLQVARDYAKGKDKKKEKGGKGKPGKVEINEQQLREILNFDGLNSQMQKSVMQMKEDFVKHLSLRSTSGAIDTLRIKVDGQEHELQELAQISRKNPKTIIVNMIGFPQTIPDVLKAIEKSGMNLNPQQDGTTLFIPIPKVTKEHRENLSKNAKALFVKYRDAIRGVQNEHIRKLKKQPELGKDDAFAAQAQVTAIADRFISEADKLLASKQKELLGD", "length": 254 }, "evidence": [ { "id": "G3X7D8", "url": "https://omabrowser.org/oma/group/G3X7D8/", "database": "OMA" } ], "glygen_name": "Fruit fly", "common_name": "Fruit fly" } ], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 1, "go_terms": [ { "name": "mitochondrion", "id": "GO:0005739", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005739", "evidence": [ { "database": "UniProtKB", "id": "G3X7D8", "url": "https://www.uniprot.org/uniprotkb/G3X7D8" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 2, "go_terms": [ { "name": "translation", "id": "GO:0006412", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006412", "evidence": [ { "database": "UniProtKB", "id": "G3X7D8", "url": "https://www.uniprot.org/uniprotkb/G3X7D8" } ], "pmid": "" }, { "name": "ribosome disassembly", "id": "GO:0032790", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0032790", "evidence": [ { "database": "UniProtKB", "id": "G3X7D8", "url": "https://www.uniprot.org/uniprotkb/G3X7D8" } ], "pmid": "" } ] }, { "name": "Molecular Function", "total": 1, "go_terms": [ { "name": "ribosomal large subunit binding", "id": "GO:0043023", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0043023", "evidence": [ { "database": "UniProtKB", "id": "G3X7D8", "url": "https://www.uniprot.org/uniprotkb/G3X7D8" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 154, "end_pos": 156, "annotation": "n_glycosylation_sequon" }, { "start_pos": 168, "end_pos": 170, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [ { "pdb_id": "AF-G3X7D8-F1", "pdb_chain": "global", "start_pos": 1, "end_pos": 312, "overlap": "1.0", "method": "AlphaFold", "type": "alphafold", "resolution": -1.0, "url": "https://data.glygen.org/ln2downloads/pdb/current/AF-G3X7D8-F1.pdb", "url_external": "https://alphafold.ebi.ac.uk/entry/G3X7D8" } ], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "G3X7D8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3X7D8" }, { "id": "PF01765", "database": "Pfam", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF01765" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "Ribosome recycling factor", "eco_id": "ECO_0000259", "start_pos": 149, "end_pos": 311, "start_aa": "Leu", "end_aa": "Leu", "glycosite_overlap": [] } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" }, { "name": "homologset.oma", "label": "OMA Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 154, "end_pos": 156 }, { "start_pos": 168, "end_pos": 170 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ], "tool_support": { "graph_view": "yes" } }, { "uniprot_canonical_ac": "G5E5N0-1", "uniprot_ac": "G5E5N0", "uniprot_id": "G5E5N0_BOVIN", "mass": { "chemical_mass": 100058.0, "monoisotopic_mass": 100058.0 }, "refseq": { "ac": "XP_005227317", "name": "p53-induced death domain-containing protein 1 isoform X4", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_005227317" }, "gene_names": [ { "name": "PIDD1", "type": "recommended", "evidence": [ { "id": "G5E5N0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G5E5N0" } ] }, { "name": "LRDD", "type": "synonym", "evidence": [ { "id": "XP_005227317", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_005227317" } ] }, { "name": "PIDD1", "type": "synonym", "evidence": [ { "id": "XP_005227317", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_005227317" } ] }, { "name": "PIDD", "type": "synonym", "evidence": [ { "id": "XP_005227317", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_005227317" } ] } ], "protein_names": [ { "name": "p53-induced death domain-containing protein 1", "type": "recommended", "evidence": [ { "id": "G5E5N0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G5E5N0/entry#names_and_taxonomy" } ] }, { "name": "Leucine-rich repeat and death domain-containing protein", "type": "synonym", "evidence": [ { "id": "G5E5N0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G5E5N0/entry#names_and_taxonomy" } ] }, { "name": "p53-induced death domain-containing protein 1 isoform X4", "type": "synonym", "evidence": [ { "id": "XP_005227317", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_005227317" } ] } ], "function": [ { "annotation": "Component of the DNA damage/stress response pathway that functions downstream of p53/TP53 and can either promote cell survival or apoptosis. Associated with CRADD and the CASP2 caspase, it forms the PIDDosome a complex that activates CASP2 and triggers apoptosis. Associated with IKBKG and RIPK1, it enhances sumoylation and ubiquitination of IKBKG which is important for activation of the transcription factor NF-kappa-B.", "evidence": [ { "database": "UniProtKB", "id": "G5E5N0", "url": "https://www.uniprot.org/uniprotkb/G5E5N0#function" }, { "database": "UniProtKB", "id": "ARBA00056062", "url": "https://www.uniprot.org/uniprotkb/ARBA00056062#function" }, { "database": "UniProtKB", "id": "A0AAA9SFH7", "url": "https://www.uniprot.org/uniprotkb/A0AAA9SFH7#function" }, { "database": "UniProtKB", "id": "A0AAA9TWG4", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TWG4#function" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Bos taurus", "taxid": 9913, "evidence": [ { "database": "UniProtKB", "id": "G5E5N0", "url": "https://www.uniprot.org/uniprotkb/G5E5N0" } ], "common_name": "Bovine", "glygen_name": "Bovine", "reference_species": "Bos taurus [9913]" } ], "gene": [ { "name": "PIDD1", "url": "https://www.uniprot.org/uniprotkb/G5E5N0", "locus": { "chromosome": "29", "start_pos": 50567587, "end_pos": 50560247, "strand": "-", "evidence": [ { "database": "Ensembl Gene", "id": "ENSBTAG00000019634", "url": "https://www.ensembl.org/id/ENSBTAG00000019634" } ] } } ], "crossref": [ { "id": "G5E5N0", "url": "https://alphafold.ebi.ac.uk/entry/G5E5N0", "database": "AlphaFoldDB", "categories": [] }, { "id": "ENSBTAG00000019634", "url": "https://bgee.org/?page=gene&gene_id=ENSBTAG00000019634", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "cd08779", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd08779", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "100137737", "url": "https://www.ncbi.nlm.nih.gov/gene/100137737", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR000488", "url": "https://www.ebi.ac.uk/interpro/entry/IPR000488", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR000906", "url": "https://www.ebi.ac.uk/interpro/entry/IPR000906", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR001611", "url": "https://www.ebi.ac.uk/interpro/entry/IPR001611", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR003591", "url": "https://www.ebi.ac.uk/interpro/entry/IPR003591", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR011029", "url": "https://www.ebi.ac.uk/interpro/entry/IPR011029", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR019502", "url": "https://www.ebi.ac.uk/interpro/entry/IPR019502", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR032675", "url": "https://www.ebi.ac.uk/interpro/entry/IPR032675", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR050216", "url": "https://www.ebi.ac.uk/interpro/entry/IPR050216", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "YPGGCHR", "url": "https://omabrowser.org/oma/group/YPGGCHR/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "PTHR48051", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR48051", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR48051:SF39", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR48051:SF39", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00531", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00531", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF00791", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00791", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF10461", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF10461", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF13855", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF13855", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "R-BTA-6803207", "url": "https://www.reactome.org/PathwayBrowser/#R-BTA-6803207", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "XP_005227317", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_005227317", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0AAA9SFH7", "url": "https://www.uniprot.org/uniprotkb/A0AAA9SFH7", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0AAA9SFH7-1", "url": "https://www.uniprot.org/uniprotkb/A0AAA9SFH7-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0AAA9TWG4", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TWG4", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0AAA9TWG4-1", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TWG4-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "G5E5N0", "url": "https://www.uniprot.org/uniprotkb/G5E5N0", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "G5E5N0-1", "url": "https://www.uniprot.org/uniprotkb/G5E5N0-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MAAMEAGPVPATLAQEDAARDASEAAGAGPEAPLLPAGNRLSLHLHPGGCRRLLRLCAQQAPQLLEVDFLQLSGHEDPQLLEAALARLPWSLPRLRSLVLKGGQRREALGACLRGSLATLPASLSSLARLAHLDLSFNSLETLPACVPQMCGLDALLLSRNCLSELPAALGALPALTFLAVTHNRLRTLPPALGALSSLQRLDLSGNLLEALPPEIGGLGSLAELNLASNRLQSLPSSLAGLRALRLFILHSNLLASVPASLARLPLLTRLDLRDNQLRDVPPELLDAPFVRLQGNPLGRPPPDPPSPPGPPVVPEMPRLLLTSDRDSFAVTPQGCSVTLACGVRLQFPAGATAAPMTIRYRLWLPEPRLVPLGPHDALLSGVLELQPHGVAFQQEVGLWLLFVPPRARRCREVVVRTLSDNSWSDLETHLEEETPKRLWAHCQVPHFSWFLVVSRPVSDACLVPPEGTLLCSSGHAGVRVTFPAGATEEPRHVRMQVVRVGSRELPALLGEPEAASSPLLCLSQSGPSSFLRPVTIQLPLPPGVTGLSLDRARLHLLHRAAPAAAWDDITAQVALELTHLYARFQVTRFSWYWLWYTTKACVGSLARKAWERLRLYRVNLIALQRRRDPEQVLLQCLPRNKVDATLRRLLERYRGPEPSDTVEMFEGEKFFAAFERGIDIDADRPDCVEGRLCFVFYSHLKNLKEVYVTTALDRRARAVRGQVSFYRGEVPEVVPEEAEAARQKRGPAALWMATLPIKLPRLQGCEGPTREPGLSLAPLNLGDAETGFLTQSNLLNVAGRLGPDWPAVALHLGLPYRELQRIRHEFRDDLDGQIRHMLFSWAERQAGQPGAVGRLVQALEQSDRRDVAEEVRAVLELGRRKYQEGIRHTSLAPGNLTSPDRLPSPSPEPAQA", "length": 913, "header": "tr|G5E5N0-1|G5E5N0_BOVIN Isoform 1 of p53-induced death domain-containing protein 1 OS=Bos taurus OX=9913 GN=PIDD1 PE=4 SV=2 CANONICAL=G5E5N0-1" }, "isoforms": [ { "isoform_ac": "A0AAA9SFH7-1", "url": "https://www.uniprot.org/uniprotkb/A0AAA9SFH7/entry", "sequence": { "sequence": "MTHYFLSLSDVPACVCVCVCVCVYSGIYVETEGGIGAGENTGLAGTARPGGEGGGKRVERCHLGQNRLEQTCMFTGTSSVTPAWRAGTCLVPEDGWWAMAAMEAGPVPATLAQEDAARDASEAAGAGPEAPLLPAGNRLSLHLHPGGCRRLLRLCAQQAPQLLEVDFLQLSGHEDPQLLEAALARLPWSLPRLRSLVLKGGQRREALGACLRGSLATLPASLSSLARLAHLDLSFNSLETLPACVPQMCGLDALLLSRNCLSELPAALGALPALTFLAVTHNRLRTLPPALGALSSLQRLDLSGNLLEALPPEIGGLGSLAELNLASNRLQSLPSSLAGLRALRLFILHSNLLASVPASLARLPLLTRLDLRDNQLRDVPPELLDAPFVRLQGNPLGRPPPDPPSPPGPPVVPEMPRLLLTSDRDSFAVTPQGCSVTLACGVRLQFPAGATAAPMTIRYRLWLPEPRLVPLGPHDALLSGVLELQPHGVAFQQEVGLWLLFVPPRARRCREVVVRTLSDNSWSDLETHLEEETPKRLWAHCQVPHFSWFLVVSRPVSDACLVPPEGTLLCSSGHAGVRVTFPAGATEEPRHVRMQVVRVGSRELPALLGEPEAASSPLLCLSQSGPSSFLRPVTIQLPLPPGVTGLSLDRARLHLLHRAAPAAAWDDITAQVALELTHLYARFQVTRFSWYWLWYTTKACVGSLARKAWERLRLYRVNLIALQRRRDPEQVLLQCLPRNKVDATLRRLLERYRGPEPSDTVEMFEGEKFFAAFERGIDIDADRPDCVEGRLCFVFYSHLKNLKEVYVTTALDRRARAVRGQVSFYRGEVPEVVPEEAEAARQKRGPAALWMATLPIKLPRLQGCEGPTREPGLSLAPLNLGDAETGFLTQSNLLNVAGRLGPDWPAVALHLGLPYRELQRIRHEFRDDLDGQIRHMLFSWAERQAGQPGAVGRLVQALEQSDRRDVAEEVRAVLELGRRKYQEGIRHTSLAPGNLTSPDRLPSPSPEPAQA", "length": 1011, "header": "tr|A0AAA9SFH7-1|G5E5N0_BOVIN Computationally mapped isoform of p53-induced death domain-containing protein 1 OS=Bos taurus OX=9913 GN=PIDD1 PE=4 SV=1 CANONICAL=G5E5N0-1" }, "locus": { "chromosome": "29", "start_pos": 50567251, "end_pos": 50560446, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000110892.1", "url": "https://www.ensembl.org/id/ENSBTAT00000110892.1" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000081211.1", "url": "https://www.ensembl.org/id/ENSBTAP00000081211.1" } ] } }, { "isoform_ac": "A0AAA9TWG4-1", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TWG4/entry", "sequence": { "sequence": "MRASASVGAEKCEGWRPAWRAGTCLVPEDGWWAMAAMEAGPVPATLAQEDAARDASEAAGAGPEAPLLPAGNRLSLHLHPGGCRRLLRLCAQQAPQLLEVDFLQLSGHEDPQLLEAALARLPWSLPRLRSLVLKGGQRREALGACLRGSLATLPASLSSLARLAHLDLSFNSLETLPACVPQMCGLDALLLSRNCLSELPAALGALPALTFLAVTHNRLRTLPPALGALSSLQRLDLSGNLLEALPPEIGGLGSLAELNLASNRLQSLPSSLAGLRALRLFILHSNLLASVPASLARLPLLTRLDLRDNQLRDVPPELLDAPFVRLQGNPLGRPPPDPPSPPGPPVVPEMPRLLLTSDRDSFAVTPQGCSVTLACGVRLQFPAGATAAPMTIRYRLWLPEPRLVPLGPHDALLSGVLELQPHGVAFQQEVGLWLLFVPPRARRCREVVVRTLSDNSWSDLETHLEEETPKRLWAHCQVPHFSWFLVVSRPVSDACLVPPEGTLLCSSGHAGVRVTFPAGATEEPRHVRMQVVRVGSRELPALLGEPEAASSPLLCLSQSGPSSFLRPVTIQLPLPPGVTGLSLDRARLHLLHRAAPAAAWDDITAQVALELTHLYARFQVTRFSWYWLWYTTKACVGSLARKAWERLRLYRVNLIALQRRRDPEQVLLQCLPRNKVDATLRRLLERYRGPEPSDTVEMFEGEKFFAAFERGIDIDADRPDCVEGRLCFVFYSHLKNLKEVYVTTALDRRARAVRGQVSFYRGEVPEVVPEEAEAARQKRGPAALWMATLPIKLPRLQGCEGPTREPGLSLAPLNLGDAETGFLTQSNLLNVAGRLGPDWPAVALHLGLPYRELQRIRHEFRDDLDGQIRHMLFSWAERQAGQPGAVGRLVQALEQSDRRDVAEEVRAVLELGRRKYQEGIRHTSLAPGNLTSPDRLPSPSPEPAQA", "length": 946, "header": "tr|A0AAA9TWG4-1|A0AAA9TWG4_BOVIN Computationally mapped isoform of p53-induced death domain-containing protein 1 OS=Bos taurus OX=9913 GN=PIDD1 PE=4 SV=1 CANONICAL=G5E5N0-1" }, "locus": { "chromosome": "29", "start_pos": 50567251, "end_pos": 50561637, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000105344.1", "url": "https://www.ensembl.org/id/ENSBTAT00000105344.1" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000101804.1", "url": "https://www.ensembl.org/id/ENSBTAP00000101804.1" } ] } }, { "isoform_ac": "G5E5N0-1", "url": "https://www.uniprot.org/uniprotkb/G5E5N0/entry", "sequence": { "sequence": "MAAMEAGPVPATLAQEDAARDASEAAGAGPEAPLLPAGNRLSLHLHPGGCRRLLRLCAQQAPQLLEVDFLQLSGHEDPQLLEAALARLPWSLPRLRSLVLKGGQRREALGACLRGSLATLPASLSSLARLAHLDLSFNSLETLPACVPQMCGLDALLLSRNCLSELPAALGALPALTFLAVTHNRLRTLPPALGALSSLQRLDLSGNLLEALPPEIGGLGSLAELNLASNRLQSLPSSLAGLRALRLFILHSNLLASVPASLARLPLLTRLDLRDNQLRDVPPELLDAPFVRLQGNPLGRPPPDPPSPPGPPVVPEMPRLLLTSDRDSFAVTPQGCSVTLACGVRLQFPAGATAAPMTIRYRLWLPEPRLVPLGPHDALLSGVLELQPHGVAFQQEVGLWLLFVPPRARRCREVVVRTLSDNSWSDLETHLEEETPKRLWAHCQVPHFSWFLVVSRPVSDACLVPPEGTLLCSSGHAGVRVTFPAGATEEPRHVRMQVVRVGSRELPALLGEPEAASSPLLCLSQSGPSSFLRPVTIQLPLPPGVTGLSLDRARLHLLHRAAPAAAWDDITAQVALELTHLYARFQVTRFSWYWLWYTTKACVGSLARKAWERLRLYRVNLIALQRRRDPEQVLLQCLPRNKVDATLRRLLERYRGPEPSDTVEMFEGEKFFAAFERGIDIDADRPDCVEGRLCFVFYSHLKNLKEVYVTTALDRRARAVRGQVSFYRGEVPEVVPEEAEAARQKRGPAALWMATLPIKLPRLQGCEGPTREPGLSLAPLNLGDAETGFLTQSNLLNVAGRLGPDWPAVALHLGLPYRELQRIRHEFRDDLDGQIRHMLFSWAERQAGQPGAVGRLVQALEQSDRRDVAEEVRAVLELGRRKYQEGIRHTSLAPGNLTSPDRLPSPSPEPAQA", "length": 913, "header": "tr|G5E5N0-1|G5E5N0_BOVIN Isoform 1 of p53-induced death domain-containing protein 1 OS=Bos taurus OX=9913 GN=PIDD1 PE=4 SV=2 CANONICAL=G5E5N0-1" }, "locus": { "chromosome": "29", "start_pos": 50567251, "end_pos": 50562069, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000026157.7", "url": "https://www.ensembl.org/id/ENSBTAT00000026157.7" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000026157.6", "url": "https://www.ensembl.org/id/ENSBTAP00000026157.6" } ] } } ], "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "other", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 332, "start_aa": "Thr", "end_pos": 332, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr332", "evidence": [ { "id": "", "database": "GlyGen", "url": "https://data.glygen.org/" } ], "filter_code": "000000000000000010000.00000000001000.0.01000" }, { "glytoucan_ac": "", "type": "O-linked", "subtype": "other", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 770, "start_aa": "Thr", "end_pos": 770, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr770", "evidence": [ { "id": "", "database": "GlyGen", "url": "https://data.glygen.org/" } ], "filter_code": "000000000000000010000.00000000001000.0.01000" } ], "phosphorylation": [], "glycation": [], "keywords": [ "glycoprotein", "glycoprotein_predicted" ], "publication": [], "pathway": [ { "id": "R-BTA-6803207", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-BTA-6803207", "resource": "Reactome", "description": "TP53 Regulates Transcription of Caspase Activators and Caspases" } ], "orthologs": [ { "uniprot_canonical_ac": "A0A8V0ZUI1-1", "protein_name": "Leucine rich repeat containing 27", "gene_name": "LRRC27", "tax_id": 9031, "organism": "Gallus gallus", "sequence": { "sequence": "MQKMAELLKLGDEHGEGDPGAPSLSGSCLADNRLTLDVYPDGCRRLLRLFEGQQAEVVQVELLRLSSNDRLLDATLSILPHLKRLKSLVLRGGHVRDEFGSCQHGSLTSLPPDVGTLRCLTHLDLSFNSLSTLPSCIPSLTSLRMLLVSHNNLVALPENFGSLSKLTFFSAMKNQLKDLPQSIGELAALEDLDLSENVLELLPEEIGNLHSCTELDLSGNRLSSIPDSLANLKSLWRLHLHSNLLVTVPASLASLPNLCRLDLQNNCLRAVPPEIQTAPFVHLRGNPLGEAEPSLQADESSATELRRLFLASEEDSFTVTSEGCEVVLACGIRFYFPPEAASDPLQIYFRTLAPDPQWVKLRHHDVLLSKVLELQPHGVKFQQEVEIWMPYASPETLHQREVVVRTFSGQSWSDLRTQVEKKRKSKKHVAHCSVLHFSWFLVVSRLVQNECKVPTEGTLLFSSVDPNIKVTFPPGVTEETRNVKLQVLPVSAEEIAELTADAGCKASPLLCLSQDSLVDFLRPVRIQLPLPFGVTGLNLDRSRLHLLCGDVEGQTWDDITSQVVLEFTHLYAVFEVTHFSWYWLWYTTKTYIGGIAKKVYERLRMYQVNFIALQRRKDPEQVLLQCLPKHKVDTVLKKLQDRYRGPEPSDMVEMFEGEQFFAAFERGISIDMDRPDCVDGRLSFIFYSHLKNMKEIYVTSPVDRKGQAVKGQVSFYRGAVPESIPEDASRRRRGPDPLWLATLPIKLPRLKPRWGETSSSLNGFSFPPLNLGNAETGYLTQANLLSIARRVGADWQTIGLNLGLTYRQIERIGYNNREDLDKQILDMLFSWAQQNSGDPDCVSKLITAMKESGRQDIADEVEAIIELGRRKYRESIRRVGLEQESSTEDSAIAMT", "length": 895 }, "evidence": [ { "id": "G5E5N0", "url": "https://omabrowser.org/oma/group/G5E5N0/", "database": "OMA" } ], "glygen_name": "Chicken", "common_name": "Chicken" }, { "uniprot_canonical_ac": "F1RYY9-1", "protein_name": "p53-induced death domain-containing protein 1", "gene_name": "PIDD1", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MCAGRSGQNRGTGRLEPPWVLPAQACLASWDMSGPRGQPVCDGCSGGGQEPEPSAAEDAARDATDAVAVGPGTLPLLAGNRLSLDLYPRGCHRLLHLCAQQVPQLLEVEFLQLSGHEDPRLLEATLAQLPSSLPHLRSLVVKGGQHRDAQGACLRGSLATLPAGLNGLVRLAHLDLSFNSLETLPACVPQMCGLGALLLSHNCLSELPEALGALCALTFLAVTHNRLQTLPTALGSLSTLQRLDLSENLLDTLPPEIGGLSSLAELNLASNRLQSLPASLAGLRSLQLLVLHSNLLASVPAGLARLPLLTRLDLRDNQLRDVPPELLDAPFVRLQGNPLSGSPPTPRSPPGTPVVPKMPSLLLSSDLDSFAVTPLGCSVTLTCGVRLRFPAGATATPVTVRYRLWLPEPRLVPLGPHDSLLSGVLELQPHGVAFQQEVGLWLLFVPPRARRCREVVVRTLSDNSWSDLETHLEEEAPKRLWAHCQVPHFSWFLVVSRPVSDACLVPPEGTLLCSSGHPGVKVTFPPGATEEPRHVRMQVVRVGSRELPALLREPEAAASPLLCLSQSGPLSFLRPVTVQLPLPPGITGLSLDRSCLHLLHRAPPAATWDDITAQVALELTHLYARFQVTRFSWYWLWYTTKACVGGLARKAWERLRLHRVNLIALQRRRDPEQVLLQCLPRHKVDATLRRLLERYRGPEPSDTVEVFEGEKFFAAFERGIAVDADRPDCVEGRVCFVFYSHLKNLKEVYVTTALDRRAQAVRGQVSFYRGEVPAEVPEEAEAARQRRGADALWMATLPIKLPRLRGSEEPAQGPGLSLAPLNLGDAETGFLTQSNLLNVAGRLGPDWPAVALHLGVPYRQLQRIRHEFRDDLDGQIRHMLFSWAERQAGQPGAVGLLVQALEQSDRRDVAEEVRAVLELGRRKYQEGIRRTSLAPGDLALRGPSSSPSPEPAQA", "length": 954 }, "evidence": [ { "id": "G5E5N0", "url": "https://omabrowser.org/oma/group/G5E5N0/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "M0R797-1", "protein_name": "p53-induced death domain-containing protein 1", "gene_name": "Pidd1", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MAAVLEGPKPEETAAAAEDAARPTVEAVASRPGVPILLAGNQLNLDLRPGGCRRLQYLCSQQHTQLLQVEFLRLSTHEDPRLLDDTLAKVPWSLLRLRSLVLKGGQSRGALGACLHGTLTTLPASMRDLACLAHLDLSFNRLETLPTCVLELHSLDALLLSHNCLSELPEALGALPTLTFLTVTHNLLERLPPTLGSLSTLQRLDLSENLLDTIPSEIGDLSSLRELNLASNRLQHLPASLAGLRSLRLLVLHSNLLTSVPPGLAHLPLITRLDLRDNQLRDLPAELLDAPFVRLQGNPLGEASPAPPSPPDISQVPEMPRLFLTSDLDSFLVTPHGCSVTLACGVRLQFPAGATTTPITIHYRLWLPEPGLVSLGPHDFLLSGVLELQPHGVAFQQNVSLWLLFVPPRVRVRRCREVVVRTRSDNIWNDLETHLEEEAPKRRWARCQVPHFSWFLVVLRPVSNTCLLPPEGALLCSSGHPGVKVTFPPGVTEEPRQVSMQVVHMAGLELRALLEESEAAVSPLLCLSQSGPPSFLQPVTVQLPLPPGVTGFSLDRSHLHLLYRTPLTSTWDDISTQVALEFTHLYARFQVTHFSWYWLWYTTKTCVGGLARKAWERLRLHRVNLIALQRRRDPEQVLLQCLPRSKVDATLSRLLDRYRGPEPSETVEMFEGEKFFAAFERGIDVDADRPDCVDGRICFVFYSHLKNMKEVYITTALDREAQDVRGQVSFYRGSLPMEVPEEAEAARRRKGTDALWMATLPIKLPRLRGAQGSGQGTDFSLMPLNLGDAETGFLTQSNLLSVASRLGSDWPTVALHLGMPYRKLQRIRHEFRDDLDGQIRHMLFSWAESQTGQPGAVGHLVQALEQSDRQDVAEEVRAILELGRHKYQDSIRRTGLAPEDSTLPSTSALQNPESAQA", "length": 917 }, "evidence": [ { "id": "G5E5N0", "url": "https://omabrowser.org/oma/group/G5E5N0/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "Q9ERV7-1", "protein_name": "p53-induced death domain-containing protein 1", "gene_name": "Pidd1", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MAAVLEGQEPEETAAAAEDAATSTLEAVDAGPGAPFLPAGNQLNLDLRPGGCHRLQYLCSQQPPQLLQVEFLRLSTHEDPQLLDDTLAKVPWSLLRLRSLVLKGGQSRGALGACLHGTLTTLPAGLSDLACLAHLDLSFNRLETLPTCVPELHGLDALLLSHNHLSELPEALGALPALTFLTVTHNRLERLPLTLGSLSTLQRLDLSENLLDTIPSEIGNLRSLSELNLASNRLQSLPASLAGLRSLRLLVLHSNLLTSVPTGLVHLPLITRLDLRDNRLRDLPAELLDAPFVRLQGNPLGEASPAPPSPPDISQVPEMPRLLLTSDLDSFLVTPHGCSVTLACGVRLQFPAGATTTPVTIHYRLWLPEPGLVSLGPHDFLLSSVLELQPHGVAFQQDVSLWLLFVPPRVRRCREVVVRTRSNNTWNDLETQLEEEAPKRLWARCQVPHFSWFLVVLRPVSNTCLLPPEGALLCSSGHPGVRVTFPPGVTEEPRQVSMQVVHMAGLELRTLLEESEASVSPLLCLSQSGPPSFLQPVTVQLPLPPGVTGFSLDRSHLHLLYRTPLTTTWDDITTQVALEFTHLYARFQVTHFSWYWLWYTTKTCVGGLARKAWERLRLHRVNLIALQRRRDPEQVLLQCLPRNKVDATLSRLLVRYRGPEPSETVEMFEGEKFFAAFERGIDVDADRPDCVDGRICFVFYSHLKNVKEVYITTALDREAQDVRGQVSFYRGSLPVEVPAEAEAARQRKGTDALWMATLPIKLPRLRGAQGSGQGTDFSLMPLNLGDAETGFLTQSNLLSVASRLGPDWPAVALHLGMPYHKLQRIRHEFRDDLDGQVRHMLFSWAERQTGQPGAVGHLVQALEQSDRRDVAEEVRAILELGRHKYQDSIRRTGLAPEDSTLPGTSASQTPESAQA", "length": 915 }, "evidence": [ { "id": "G5E5N0", "url": "https://omabrowser.org/oma/group/G5E5N0/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q9HB75-1", "protein_name": "p53-induced death domain-containing protein 1", "gene_name": "PIDD1", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MAATVEGPELEAAAAAGDASEDSDAGSRALPFLGGNRLSLDLYPGGCQQLLHLCVQQPLQLLQVEFLRLSTHEDPQLLEATLAQLPQSLSCLRSLVLKGGQRRDTLGACLRGALTNLPAGLSGLAHLAHLDLSFNSLETLPACVLQMRGLGALLLSHNCLSELPEALGALPALTFLTVTHNRLQTLPPALGALSTLQRLDLSQNLLDTLPPEIGGLGSLLELNLASNRLQSLPASLAGLRSLRLLVLHSNLLASVPADLARLPLLTRLDLRDNQLRDLPPELLDAPFVRLQGNPLGEASPDAPSSPVAALIPEMPRLFLTSDLDSFPVTPQGCSVTLACGVRLQFPAGATATPITIRYRLLLPEPGLVPLGPHDALLSHVLELQPHGVAFQQDVGLWLLFTPPQARRCREVVVRTRNDNSWGDLETYLEEEAPQRLWAHCQVPHFSWFLVVSRPVSNACLVPPEGTLLCSSGHPGVKVIFPPGATEEPRRVSMQVVRMAGRELQALLGEPEAAVSPLLCLSQSGPPSFLQPVTVQLPLPSGITGLSLDRSRLHLLYWAPPAATWDDITAQVVLELTHLYARFQVTHFSWYWLWYTTKNCVGGLARKAWERLRLHRVNLIALQRRRDPEQVLLQCLPRNKVDATLRRLLERYRGPEPSDTVEMFEGEEFFAAFERGIDVDADRPDCVEGRICFVFYSHLKNVKEVYVTTTLDREAQAVRGQVSFYRGAVPVRVPEEAEAARQRKGADALWMATLPIKLPRLRGSEGPRRGAGLSLAPLNLGDAETGFLTQSNLLSVAGRLGLDWPAVALHLGVSYREVQRIRHEFRDDLDEQIRHMLFSWAERQAGQPGAVGLLVQALEQSDRQDVAEEVRAVLELGRRKYQDSIRRMGLAPKDPALPGSSAPQPPEPAQA", "length": 910 }, "evidence": [ { "id": "G5E5N0", "url": 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autoprocessing", "id": "GO:0016540", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016540", "evidence": [ { "database": "UniProtKB", "id": "G5E5N0", "url": "https://www.uniprot.org/uniprotkb/G5E5N0" } ], "pmid": "" }, { "name": "regulation of canonical NF-kappaB signal transduction", "id": "GO:0043122", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0043122", "evidence": [ { "database": "UniProtKB", "id": "G5E5N0", "url": "https://www.uniprot.org/uniprotkb/G5E5N0" } ], "pmid": "" }, { "name": "DNA damage response, signal transduction by p53 class mediator", "id": "GO:0030330", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030330", "evidence": [ { "database": "UniProtKB", "id": "G5E5N0", "url": "https://www.uniprot.org/uniprotkb/G5E5N0" } ], "pmid": "" }, { "name": "intracellular signal transduction", "id": "GO:0035556", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0035556", "evidence": [ { "database": "UniProtKB", "id": "G5E5N0", "url": "https://www.uniprot.org/uniprotkb/G5E5N0" } ], "pmid": "" }, { "name": "DNA damage response", "id": "GO:0006974", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006974", "evidence": [ { "database": "UniProtKB", "id": "G5E5N0", "url": "https://www.uniprot.org/uniprotkb/G5E5N0" } ], "pmid": "" }, { "name": "signal transduction", "id": "GO:0007165", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007165", "evidence": [ { "database": "UniProtKB", "id": "G5E5N0", "url": "https://www.uniprot.org/uniprotkb/G5E5N0" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 896, "end_pos": 898, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [ { "pdb_id": "AF-G5E5N0-F1", "pdb_chain": "global", "start_pos": 1, "end_pos": 913, "overlap": "1.0", "method": "AlphaFold", "type": "alphafold", "resolution": -1.0, "url": "https://data.glygen.org/ln2downloads/pdb/current/AF-G5E5N0-F1.pdb", "url_external": "https://alphafold.ebi.ac.uk/entry/G5E5N0" } ], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "G5E5N0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G5E5N0" }, { "id": "PS50017", "database": "PROSITE", "url": "https://prosite.expasy.org/PS50017" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "Death", "eco_id": "ECO_0000259", "start_pos": 791, "end_pos": 876, "start_aa": "Thr", "end_aa": "Leu", "glycosite_overlap": [] }, { "evidence": [ { "id": "G5E5N0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G5E5N0" }, { "id": "PS51145", "database": "PROSITE", "url": "https://prosite.expasy.org/PS51145" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "ZU5", "eco_id": "ECO_0000259", "start_pos": 325, "end_pos": 457, "start_aa": "Asp", "end_aa": "Pro", "glycosite_overlap": [] } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" }, { "name": "homologset.oma", "label": "OMA Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [ 332, 770 ], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 896, "end_pos": 898 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 2 }, { "field": "total_sites", "count": 2 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 2 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "exact_sites", "count": 2 }, { "field": "exact_o_linked_sites", "count": 2 }, { "field": "fuzzy_sites", "count": 0 } ], "sort_fields": [ "glytoucan_ac", 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"yes" } }, { "uniprot_canonical_ac": "G3MYQ0-1", "uniprot_ac": "G3MYQ0", "uniprot_id": "G3MYQ0_BOVIN", "mass": { "chemical_mass": 25503.0, "monoisotopic_mass": 25503.0 }, "refseq": { "ac": "NP_001180057", "name": "serine/threonine/tyrosine-interacting protein", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001180057" }, "gene_names": [ { "name": "STYX", "type": "recommended", "evidence": [ { "id": "G3MYQ0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3MYQ0" } ] }, { "name": "STYX", "type": "synonym", "evidence": [ { "id": "NP_001180057", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001180057" } ] } ], "protein_names": [ { "name": "Serine/threonine/tyrosine-interacting protein", "type": "recommended", "evidence": [ { "id": "G3MYQ0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3MYQ0/entry#names_and_taxonomy" } ] }, { "name": "Inactive tyrosine-protein phosphatase STYX", "type": "synonym", "evidence": [ { "id": "G3MYQ0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3MYQ0/entry#names_and_taxonomy" } ] }, { "name": "Phosphoserine/threonine/tyrosine interaction protein", "type": "synonym", "evidence": [ { "id": "G3MYQ0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3MYQ0/entry#names_and_taxonomy" } ] }, { "name": "serine/threonine/tyrosine-interacting protein", "type": "synonym", "evidence": [ { "id": "NP_001180057", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001180057" } ] } ], "function": [ { "annotation": "Catalytically inactive phosphatase. Acts as a nuclear anchor for MAPK1/MAPK3 (ERK1/ERK2). Modulates cell-fate decisions and cell migration by spatiotemporal regulation of MAPK1/MAPK3 (ERK1/ERK2). By binding to the F-box of FBXW7, prevents the assembly of FBXW7 into the SCF E3 ubiquitin-protein ligase complex, and thereby inhibits degradation of its substrates. Plays a role in spermatogenesis.", "evidence": [ { "database": "UniProtKB", "id": "A0AAA9U267", "url": "https://www.uniprot.org/uniprotkb/A0AAA9U267#function" }, { "database": "UniProtKB", "id": "ARBA00054356", "url": "https://www.uniprot.org/uniprotkb/ARBA00054356#function" }, { "database": "UniProtKB", "id": "A0AAA9THJ0", "url": "https://www.uniprot.org/uniprotkb/A0AAA9THJ0#function" }, { "database": "UniProtKB", "id": "A0AAA9TNB4", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TNB4#function" }, { "database": "UniProtKB", "id": "A0AAA9SFV1", "url": "https://www.uniprot.org/uniprotkb/A0AAA9SFV1#function" }, { "database": "UniProtKB", "id": "G3MYQ0", "url": "https://www.uniprot.org/uniprotkb/G3MYQ0#function" }, { "database": "UniProtKB", "id": "A0AAA9TLB2", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TLB2#function" }, { "database": "UniProtKB", "id": "A0AAA9TX11", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TX11#function" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Bos taurus", "taxid": 9913, "evidence": [ { "database": "UniProtKB", "id": "G3MYQ0", "url": "https://www.uniprot.org/uniprotkb/G3MYQ0" } ], "common_name": "Bovine", "glygen_name": "Bovine", "reference_species": "Bos taurus [9913]" } ], "gene": [ { "name": "STYX", "url": "https://www.uniprot.org/uniprotkb/G3MYQ0", "locus": { "chromosome": "10", "start_pos": 11353085, "end_pos": 11460259, "strand": "+", "evidence": [ { "database": "Ensembl Gene", "id": "ENSBTAG00000046956", "url": "https://www.ensembl.org/id/ENSBTAG00000046956" } ] } } ], "crossref": [ { "id": "G3MYQ0", "url": "https://alphafold.ebi.ac.uk/entry/G3MYQ0", "database": "AlphaFoldDB", "categories": [] }, { "id": "ENSBTAG00000046956", "url": "https://bgee.org/?page=gene&gene_id=ENSBTAG00000046956", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "cd14522", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd14522", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "616825", "url": "https://www.ncbi.nlm.nih.gov/gene/616825", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR000340", "url": "https://www.ebi.ac.uk/interpro/entry/IPR000340", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR000387", "url": "https://www.ebi.ac.uk/interpro/entry/IPR000387", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR020422", "url": "https://www.ebi.ac.uk/interpro/entry/IPR020422", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR029021", "url": "https://www.ebi.ac.uk/interpro/entry/IPR029021", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR052449", "url": "https://www.ebi.ac.uk/interpro/entry/IPR052449", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "bta:616825", "url": 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"categories": [ "Protein" ] }, { "id": "A0AAA9SFV1", "url": "https://www.uniprot.org/uniprotkb/A0AAA9SFV1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0AAA9SFV1-1", "url": "https://www.uniprot.org/uniprotkb/A0AAA9SFV1-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0AAA9THJ0", "url": "https://www.uniprot.org/uniprotkb/A0AAA9THJ0", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0AAA9THJ0-1", "url": "https://www.uniprot.org/uniprotkb/A0AAA9THJ0-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0AAA9TLB2", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TLB2", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0AAA9TLB2-1", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TLB2-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0AAA9TNB4", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TNB4", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0AAA9TNB4-1", 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"MEDVKLEFPSLPQCKEDAEEWTYPMRREMQEILPGLFLGPYSSAMKSKLPILQKHGITHIICIRQNIEANFIKPNFQQLFRYLVLDIADNPVENIIRFFPMTKEFIDESLQSGGKVLVHGNAGISRSAAFVIAYIMETFGMKYRDAFAYVQERRFCINPNAGFVHQLQEYEAIYLAKLTIQMMSPLQIERSLSVHSGSTGSLKRTHEEEDDFGNMQVAAAQNG", "length": 223, "header": "tr|G3MYQ0-1|G3MYQ0_BOVIN Isoform 1 of Serine/threonine/tyrosine-interacting protein OS=Bos taurus OX=9913 GN=STYX PE=3 SV=1 CANONICAL=G3MYQ0-1" }, "isoforms": [ { "isoform_ac": "A0AAA9SFV1-1", "url": "https://www.uniprot.org/uniprotkb/A0AAA9SFV1/entry", "sequence": { "sequence": "MEDVKLEFPSLPQCKEDAEEILPGLFLGPYSSAMKSKLPILQKHGITHIICIRQNIEANFIKPNFQQLFRYLVLDIADNPVENIIRFFPMTKEFIDESLQSGGKVLVHGNAGISRSAAFVIAYIMETFGMKYRDAFAYVQERRFCINPNAGFVHQLQEYEAIYLAKLTIQMMSPLQIERSLSVHSGSTGSLKRTHEEEDDFGNMQVAAAQNG", "length": 212, "header": "tr|A0AAA9SFV1-1|G3MYQ0_BOVIN Computationally mapped isoform of Serine/threonine/tyrosine-interacting protein OS=Bos taurus OX=9913 GN=STYX PE=3 SV=1 CANONICAL=G3MYQ0-1" }, "locus": { "chromosome": "10", "start_pos": 11459963, "end_pos": 11410285, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000115708.1", "url": "https://www.ensembl.org/id/ENSBTAT00000115708.1" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000082498.1", "url": "https://www.ensembl.org/id/ENSBTAP00000082498.1" } ] } }, { "isoform_ac": "A0AAA9THJ0-1", "url": "https://www.uniprot.org/uniprotkb/A0AAA9THJ0/entry", "sequence": { "sequence": "MEDVKLEFPSLPQCKEDAEEWTYPMRREMQEILPGLFLGPYSSAMKSKLPILQKHGITHIICIRQNIEANFIKPNFQQLFRYLVLDIADNPVENIIRFFPMTKEFIDESLQSGGKVLVHGNAGISRSAAFVIAYIMETFGMKYRDAFAYVQERRFCINPNAGFVHQLQGIKFSLQSSFYIREELVPGPYTLPHHGFQISCKMA", "length": 203, "header": "tr|A0AAA9THJ0-1|G3MYQ0_BOVIN Computationally mapped isoform of Serine/threonine/tyrosine-interacting protein OS=Bos taurus OX=9913 GN=STYX PE=3 SV=1 CANONICAL=G3MYQ0-1" }, "locus": { "chromosome": "10", "start_pos": 11459963, "end_pos": 11418320, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000133400.1", "url": "https://www.ensembl.org/id/ENSBTAT00000133400.1" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000096549.1", "url": "https://www.ensembl.org/id/ENSBTAP00000096549.1" } ] } }, { "isoform_ac": "A0AAA9TLB2-1", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TLB2/entry", "sequence": { "sequence": "MEDVKLEFPSLPQCKEDAEEWTYPMRREMQEILPGLFLGPYSSAMKSKLPILQKHGITHIICIRQNIEANFIKPNFQQLFRYLVLDIADNPVENIIRFFPMTKEFIDESLQSGGKVLVHGNAGISRRDAFAYVQERRFCINPNAGFVHQLQEYEAIYLAKLTIQMMSPLQIERSLSVHSGSTGSLKRTHEEEDDFGNMQVAAAQNG", "length": 206, "header": "tr|A0AAA9TLB2-1|G3MYQ0_BOVIN Computationally mapped isoform of Serine/threonine/tyrosine-interacting protein OS=Bos taurus OX=9913 GN=STYX PE=3 SV=1 CANONICAL=G3MYQ0-1" }, "locus": { "chromosome": "10", "start_pos": 11459963, "end_pos": 11410285, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000111551.1", "url": "https://www.ensembl.org/id/ENSBTAT00000111551.1" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000097988.1", "url": "https://www.ensembl.org/id/ENSBTAP00000097988.1" } ] } }, { "isoform_ac": "A0AAA9TNB4-1", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TNB4/entry", "sequence": { "sequence": "MEDVKLEFPSLPQCKEDAEEWTYPMRREMQEILPGLFLGPYSSAMKSKLPILQKHGITHIICIRQNIEANFIKPNFQQLFRYLVLDIADNPVENIIRFFPMTKEFIDESLQSGGKVLVHGNAGISRSAAFVIAYIMETFGMKYRDAFAYVQERRFCINPNAGFVHQLQEYEAIYLAKLTIQMMSPLQIERSLSVHSGSTAPDDYHSTSCLCEF", "length": 213, "header": "tr|A0AAA9TNB4-1|G3MYQ0_BOVIN Computationally mapped isoform of Serine/threonine/tyrosine-interacting protein OS=Bos taurus OX=9913 GN=STYX PE=3 SV=1 CANONICAL=G3MYQ0-1" }, "locus": { "chromosome": "10", "start_pos": 11459963, "end_pos": 11353118, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000111971.1", "url": "https://www.ensembl.org/id/ENSBTAT00000111971.1" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000098758.1", "url": "https://www.ensembl.org/id/ENSBTAP00000098758.1" } ] } }, { "isoform_ac": "A0AAA9TX11-1", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TX11/entry", "sequence": { "sequence": "MEDVKLEFPSLPQCKEDAEEWTYPMRREMQEILPGLFLGPYSSAMKSKLPILQKHGITHIICIRQNIEANFIKPNFQQLFRYLVLDIADNPVENIIRFFPMTKEFIDESLQSGGKVLVHGNAGISRSAAFVIAYIMETFGMKYRDAFAYVQERRFCINPNAGFVHQLQEYEAIYLAKLTIQMMSPLQIERSLSVHSGSTGGDLRSRIRSSSGS", "length": 213, "header": "tr|A0AAA9TX11-1|A0AAA9TX11_BOVIN Computationally mapped isoform of Serine/threonine/tyrosine-interacting protein OS=Bos taurus OX=9913 GN=STYX PE=3 SV=1 CANONICAL=G3MYQ0-1" }, "locus": { "chromosome": "10", "start_pos": 11459963, "end_pos": 11393249, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000112445.1", "url": "https://www.ensembl.org/id/ENSBTAT00000112445.1" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000102897.1", "url": "https://www.ensembl.org/id/ENSBTAP00000102897.1" } ] } }, { "isoform_ac": "A0AAA9U267-1", "url": "https://www.uniprot.org/uniprotkb/A0AAA9U267/entry", "sequence": { "sequence": "MEDVKLEFPSLPQCKEDAEEWTYPMRREMQEILPGLFLGPYSSAMKSKLPILQKHGITHIICIRQNIEANFIKPNFQQLFRYLVLDIADNPVENIIRFFPMTKEFIDESLQSGGKVLVHGNAGISRSAAFVIAYIMETFGMKYRDAFAYVQERRFCINPNAGFVHQLQEYEAIYLAKLTIQMMSPLQIERSLSVHSGSTVLL", "length": 202, "header": "tr|A0AAA9U267-1|A0AAA9U267_BOVIN Computationally mapped isoform of Serine/threonine/tyrosine-interacting protein OS=Bos taurus OX=9913 GN=STYX PE=3 SV=1 CANONICAL=G3MYQ0-1" }, "locus": { "chromosome": "10", "start_pos": 11459963, "end_pos": 11410044, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000114669.1", "url": "https://www.ensembl.org/id/ENSBTAT00000114669.1" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000103496.1", "url": "https://www.ensembl.org/id/ENSBTAP00000103496.1" } ] } }, { "isoform_ac": "G3MYQ0-1", "url": "https://www.uniprot.org/uniprotkb/G3MYQ0/entry", "sequence": { "sequence": "MEDVKLEFPSLPQCKEDAEEWTYPMRREMQEILPGLFLGPYSSAMKSKLPILQKHGITHIICIRQNIEANFIKPNFQQLFRYLVLDIADNPVENIIRFFPMTKEFIDESLQSGGKVLVHGNAGISRSAAFVIAYIMETFGMKYRDAFAYVQERRFCINPNAGFVHQLQEYEAIYLAKLTIQMMSPLQIERSLSVHSGSTGSLKRTHEEEDDFGNMQVAAAQNG", "length": 223, "header": "tr|G3MYQ0-1|G3MYQ0_BOVIN Isoform 1 of Serine/threonine/tyrosine-interacting protein OS=Bos taurus OX=9913 GN=STYX PE=3 SV=1 CANONICAL=G3MYQ0-1" }, "locus": { "chromosome": "10", "start_pos": 11459963, "end_pos": 11410285, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000063138.3", "url": "https://www.ensembl.org/id/ENSBTAT00000063138.3" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000054687.1", "url": "https://www.ensembl.org/id/ENSBTAP00000054687.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [ { "id": "bta:616825", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?bta:616825", "resource": "KEGG Pathway" } ], "orthologs": [ { "uniprot_canonical_ac": "A0A3Q2U9J8-1", "protein_name": "Serine/threonine/tyrosine interacting protein", "gene_name": "STYX", "tax_id": 9031, "organism": "Gallus gallus", "sequence": { "sequence": "MELAKPAFPALPQAKEDSEDWTYPMRREMQEILPGLFLGPYSSAMKSKLPILQKHGITHVICIRQNIEANFIKPNFQQLFRYLVLDIADNPVENIIRFFPMTKEFIDGSLQSGGKVLVHGNAGISRSAALVIAYIMETFGVKYRDAFTYVQERRFCINPNAGFVHQLQEYEAIYLAKLTIQMMSPLQLERSLSVPPGATGSLKRMHEEDEELGTMQVAAAQNG", "length": 223 }, "evidence": [ { "id": "G3MYQ0", "url": "https://omabrowser.org/oma/group/G3MYQ0/", "database": "OMA" } ], "glygen_name": "Chicken", "common_name": "Chicken" }, { "uniprot_canonical_ac": "A0A8I5ZMB8-1", "protein_name": "Serine/threonine/tyrosine-interacting protein", "gene_name": "Styx", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MEDVKLEFPSLPQCKDDAEEWTYPMRREMQEVLPGLFLGPYSSAMKSKLPILQKHGITHIICIRQNIEANFIKPNFQQLFRYLVLDIADNPVENIIRFFPMTKEFIDGSLQNGGKVLVHGNAGISRSAAFVIAYIMETFGMKYRDAFAYVQERRFCINPNAGFVHQLQEYEAIYLAKLTIQMMSPLQIERSLSVHSGTTGSVKRTYEDDDDFGNMQVATAQNG", "length": 223 }, "evidence": [ { "id": "G3MYQ0", "url": "https://omabrowser.org/oma/group/G3MYQ0/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "G3I6I0-1", "protein_name": "Serine/threonine/tyrosine-interacting protein", "gene_name": "Styx", "tax_id": 10029, "organism": "Cricetulus griseus", "sequence": { "sequence": "MEDVKLEFPSLPQCKDYAEEWTYPMRREMQEVLPGLFLGPYSSAMKSKLPILQKHGITHIICIRQNIEANFIKPNFQQLFRYLVLDIADNPVENIIRFFPMTKEFIDGSLQNGGKVLVHGNAGISRSAAFVIAYIMETFGMKYRDAFAYVQERRFCINPNAGFVHQLQEYEAIYLAKLTIQMMSPLQIERSLTVHSGTTGSLKRTHEEEDDFGNMQVATAQNG", "length": 223 }, "evidence": [ { "id": "G3MYQ0", "url": "https://omabrowser.org/oma/group/G3MYQ0/", "database": "OMA" } ], "glygen_name": "Hamster", "common_name": "Chinese hamster" }, { "uniprot_canonical_ac": "Q60969-1", "protein_name": "Serine/threonine/tyrosine-interacting protein", "gene_name": "Styx", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MEDVKLEFPSLPQCKDDAEEWTYPMRREMQEVLPGLFLGPYSSAMKSKLPILQKHGITHIICIRQNIEANFIKPNFQQLFRYLVLDIADNPVENIIRFFPMTKEFIDGSLQNGGKVLVHGNAGISRSAAFVIAYIMETFGMKYRDAFAYVQERRFCINPNAGFVHQLQEYEAIYLAKLTIQMMSPLQIERSLAVHSGTTGSVKRTHEEDDDFGNMQVATAQNG", "length": 223 }, "evidence": [ { "id": "G3MYQ0", "url": "https://omabrowser.org/oma/group/G3MYQ0/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q8WUJ0-1", "protein_name": "Serine/threonine/tyrosine-interacting protein", "gene_name": "STYX", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MEDVKLEFPSLPQCKEDAEEWTYPMRREMQEILPGLFLGPYSSAMKSKLPVLQKHGITHIICIRQNIEANFIKPNFQQLFRYLVLDIADNPVENIIRFFPMTKEFIDGSLQMGGKVLVHGNAGISRSAAFVIAYIMETFGMKYRDAFAYVQERRFCINPNAGFVHQLQEYEAIYLAKLTIQMMSPLQIERSLSVHSGTTGSLKRTHEEEDDFGTMQVATAQNG", "length": 223 }, "evidence": [ { "id": "G3MYQ0", "url": "https://omabrowser.org/oma/group/G3MYQ0/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" } ], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 2, "go_terms": [ { "name": "cytoplasm", "id": "GO:0005737", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005737", "evidence": [ { "database": "UniProtKB", "id": "G3MYQ0", "url": "https://www.uniprot.org/uniprotkb/G3MYQ0" } ], "pmid": "" }, { "name": "nucleoplasm", "id": "GO:0005654", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005654", "evidence": [ { "database": "UniProtKB", "id": "G3MYQ0", "url": "https://www.uniprot.org/uniprotkb/G3MYQ0" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 2, "go_terms": [ { "name": "regulation of ERK1 and ERK2 cascade", "id": "GO:0070372", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0070372", "evidence": [ { "database": "UniProtKB", "id": "G3MYQ0", "url": "https://www.uniprot.org/uniprotkb/G3MYQ0" } ], "pmid": "" }, { "name": "negative regulation of SCF-dependent proteasomal ubiquitin-dependent catabolic process", "id": "GO:0062026", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0062026", "evidence": [ { "database": "UniProtKB", "id": "G3MYQ0", "url": "https://www.uniprot.org/uniprotkb/G3MYQ0" } ], "pmid": "" } ] }, { "name": "Molecular Function", "total": 2, "go_terms": [ { "name": "F-box domain binding", "id": "GO:1990444", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:1990444", "evidence": [ { "database": "UniProtKB", "id": "G3MYQ0", "url": "https://www.uniprot.org/uniprotkb/G3MYQ0" } ], "pmid": "" }, { "name": "pseudophosphatase activity", "id": "GO:0001691", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0001691", "evidence": [ { "database": "UniProtKB", "id": "G3MYQ0", "url": "https://www.uniprot.org/uniprotkb/G3MYQ0" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [ { "pdb_id": "AF-G3MYQ0-F1", "pdb_chain": "global", "start_pos": 1, "end_pos": 223, "overlap": "1.0", "method": "AlphaFold", "type": "alphafold", "resolution": -1.0, "url": "https://data.glygen.org/ln2downloads/pdb/current/AF-G3MYQ0-F1.pdb", "url_external": "https://alphafold.ebi.ac.uk/entry/G3MYQ0" } ], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "G3MYQ0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3MYQ0" }, { "id": "PS50056", "database": "PROSITE", "url": "https://prosite.expasy.org/PS50056" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "Tyrosine specific protein phosphatases", "eco_id": "ECO_0000259", "start_pos": 96, "end_pos": 154, "start_aa": "Ile", "end_aa": "Arg", "glycosite_overlap": [] }, { "evidence": [ { "id": "G3MYQ0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3MYQ0" }, { "id": "PS50054", "database": "PROSITE", "url": "https://prosite.expasy.org/PS50054" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "Tyrosine-protein phosphatase", "eco_id": "ECO_0000259", "start_pos": 28, "end_pos": 176, "start_aa": "Glu", "end_aa": "Ala", "glycosite_overlap": [] } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" }, { "name": "homologset.oma", "label": "OMA Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": 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{ "database": "UniProtKB", "id": "G5E539", "url": "https://www.uniprot.org/uniprotkb/G5E539#function" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Bos taurus", "taxid": 9913, "evidence": [ { "database": "UniProtKB", "id": "G5E539", "url": "https://www.uniprot.org/uniprotkb/G5E539" } ], "common_name": "Bovine", "glygen_name": "Bovine", "reference_species": "Bos taurus [9913]" } ], "gene": [ { "name": "ZNF674", "url": "https://www.uniprot.org/uniprotkb/G5E539", "locus": { "chromosome": "X", "start_pos": 97434266, "end_pos": 97468445, "strand": "+", "evidence": [ { "database": "Ensembl Gene", "id": "ENSBTAG00000002956", "url": "https://www.ensembl.org/id/ENSBTAG00000002956" } ] } } ], "crossref": [ { "id": "G5E539", "url": "https://alphafold.ebi.ac.uk/entry/G5E539", "database": "AlphaFoldDB", "categories": [] }, { "id": "cd07765", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd07765", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "514769", "url": "https://www.ncbi.nlm.nih.gov/gene/514769", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR001909", "url": "https://www.ebi.ac.uk/interpro/entry/IPR001909", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR013087", "url": "https://www.ebi.ac.uk/interpro/entry/IPR013087", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR036051", "url": "https://www.ebi.ac.uk/interpro/entry/IPR036051", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR036236", "url": "https://www.ebi.ac.uk/interpro/entry/IPR036236", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR050752", "url": "https://www.ebi.ac.uk/interpro/entry/IPR050752", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "PTHR24384", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR24384", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR24384:SF242", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR24384:SF242", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR24399", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR24399", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR24399:SF49", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR24399:SF49", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00096", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00096", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF01352", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF01352", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "A0AAA9SFV2", "url": 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"MVMSQETLTFRDVFVDFTQEEWQQLDAAQKNLHRDVMLENYSHLVSVGYLVAQPHGIFRLGQGEEEARIAAGESVIWSCPGSSQWTGPECPVSCIEPGLAIYFTYEFWKVNDQTDNHKESQDKLLWQAASINKETLKDKSGQEFRTYGEIIYPSTGFVSIGQRLTKYYSWGKCSKHNFNFLSQSRSCVRKKGDECKAYWKLCFHSNLDKAQSGEKFFEPNEHGKALHCKQALNKSPRIQNGEKLYQCSECGKVFIQKANLVVHQRTHTGEKPYECCDCAKTFSQKSTLIAHQRTHTGEKPYECSECGKTFIQKSTLMKHQRTHTGEKPFVCGECAKAFKSSYHLIRHEKTHIRQAFYEAIKCDKSRLIYQRTHMGEKSECNKHGKGFNETPTPIKHQLTHTEETLYECSKCGKGFRGKSHLSVHQRVHTREKSYECSICGKTFSGKSHLSVHHRIHTGEKPYECRRCGKAFGEKSTLIVHQRTHTGEKPYKCNECGKAFSEKSPLIKHQRIHTGERPYECSECRKTFSRKSTLIKHQRIHTGEKPYECSECGKAFSVKSTLIVHHRTHTGEKPYECRECDKAFSGKSTLIKHQKSHTGDKTY", "length": 602, "header": "tr|G5E539-1|G5E539_BOVIN Isoform 1 of Zinc finger protein 674 OS=Bos taurus OX=9913 GN=ZNF674 PE=3 SV=1 CANONICAL=G5E539-1" }, "isoforms": [ { "isoform_ac": "A0AAA9SFV2-1", "url": "https://www.uniprot.org/uniprotkb/A0AAA9SFV2/entry", "sequence": { "sequence": 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"database": "Ensembl Peptide", "id": "ENSBTAP00000085060.1", "url": "https://www.ensembl.org/id/ENSBTAP00000085060.1" } ] } }, { "isoform_ac": "A0AAA9T4B5-1", "url": "https://www.uniprot.org/uniprotkb/A0AAA9T4B5/entry", "sequence": { "sequence": "MESTPGRIFEPKETLTFRDVFVDFTQEEWQQLDAAQKNLHRDVMLENYSHLVSVGYLVAQPHGIFRLGQGEEEARIAAGESVIWSCPEFWKVNDQTDNHKESQDKLLWQAASINKETLKDKSGQEFRTYGEIIYPSTGFVSIGQRLTKYYSWGKCSKHNFNFLSQSRSCVRKKGDECKAYWKLCFHSNLDKAQSGEKFFEPNEHGKALHCKQALNKSPRIQNGEKLYQCSECGKVFIQKANLVVHQRTHTGEKPYECCDCAKTFSQKSTLIAHQRTHTGEKPYECSECGKTFIQKSTLMKHQRTHTGEKPFVCGECAKAFKSSYHLIRHEKTHIRQAFYEAIKCDKSRLIYQRTHMGEKSECNKHGKGFNETPTPIKHQLTHTEETLYECSKCGKGFRGKSHLSVHQRVHTREKSYECSICGKTFSGKSHLSVHHRIHTGEKPYECRRCGKAFGEKSTLIVHQRTHTGEKPYKCNECGKAFSEKSPLIKHQRIHTGERPYECSECRKTFSRKSTLIKHQRIHTGEKPYECSECGKAFSVKSTLIVHHRTHTGEKPYECRECDKAFSGKSTLIKHQKSHTGDKTY", "length": 584, "header": "tr|A0AAA9T4B5-1|G5E539_BOVIN Computationally mapped isoform of Zinc finger protein 674 OS=Bos taurus OX=9913 GN=ZNF674 PE=3 SV=1 CANONICAL=G5E539-1" }, "locus": { "chromosome": "X", "start_pos": 97464294, "end_pos": 97435744, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000104219.2", "url": "https://www.ensembl.org/id/ENSBTAT00000104219.2" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000090566.1", "url": "https://www.ensembl.org/id/ENSBTAP00000090566.1" } ] } }, { "isoform_ac": "G5E539-1", "url": "https://www.uniprot.org/uniprotkb/G5E539/entry", "sequence": { "sequence": "MVMSQETLTFRDVFVDFTQEEWQQLDAAQKNLHRDVMLENYSHLVSVGYLVAQPHGIFRLGQGEEEARIAAGESVIWSCPGSSQWTGPECPVSCIEPGLAIYFTYEFWKVNDQTDNHKESQDKLLWQAASINKETLKDKSGQEFRTYGEIIYPSTGFVSIGQRLTKYYSWGKCSKHNFNFLSQSRSCVRKKGDECKAYWKLCFHSNLDKAQSGEKFFEPNEHGKALHCKQALNKSPRIQNGEKLYQCSECGKVFIQKANLVVHQRTHTGEKPYECCDCAKTFSQKSTLIAHQRTHTGEKPYECSECGKTFIQKSTLMKHQRTHTGEKPFVCGECAKAFKSSYHLIRHEKTHIRQAFYEAIKCDKSRLIYQRTHMGEKSECNKHGKGFNETPTPIKHQLTHTEETLYECSKCGKGFRGKSHLSVHQRVHTREKSYECSICGKTFSGKSHLSVHHRIHTGEKPYECRRCGKAFGEKSTLIVHQRTHTGEKPYKCNECGKAFSEKSPLIKHQRIHTGERPYECSECRKTFSRKSTLIKHQRIHTGEKPYECSECGKAFSVKSTLIVHHRTHTGEKPYECRECDKAFSGKSTLIKHQKSHTGDKTY", "length": 602, "header": "tr|G5E539-1|G5E539_BOVIN Isoform 1 of Zinc finger protein 674 OS=Bos taurus OX=9913 GN=ZNF674 PE=3 SV=1 CANONICAL=G5E539-1" }, "locus": { "chromosome": "X", "start_pos": 97465361, "end_pos": 97435744, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000003850.6", "url": "https://www.ensembl.org/id/ENSBTAT00000003850.6" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000003850.5", "url": "https://www.ensembl.org/id/ENSBTAP00000003850.5" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [], "orthologs": [], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 1, "go_terms": [ { "name": "nucleus", "id": "GO:0005634", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005634", "evidence": [ { "database": "UniProtKB", "id": "G5E539", "url": "https://www.uniprot.org/uniprotkb/G5E539" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 3, "go_terms": [ { "name": "DNA-templated transcription", "id": "GO:0006351", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006351", "evidence": [ { "database": "UniProtKB", "id": "G5E539", "url": "https://www.uniprot.org/uniprotkb/G5E539" } ], "pmid": "" }, { "name": "negative regulation of DNA-templated transcription", "id": "GO:0045892", "url": 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"url": "https://prosite.expasy.org/PS50805" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "KRAB", "eco_id": "ECO_0000259", "start_pos": 8, "end_pos": 79, "start_aa": "Leu", "end_aa": "Cys", "glycosite_overlap": [] } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 233, "end_pos": 235 }, { "start_pos": 388, "end_pos": 390 }, { "start_pos": 40, "end_pos": 42 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": 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{ "name": "TMEM176B", "type": "recommended", "evidence": [ { "id": "F6RY68", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F6RY68" } ] } ], "protein_names": [ { "name": "Transmembrane protein 176B", "type": "synonym", "evidence": [ { "id": "F6RY68", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F6RY68/entry#names_and_taxonomy" } ] } ], "function": [], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Bos taurus", "taxid": 9913, "evidence": [ { "database": "UniProtKB", "id": "F6RY68", "url": "https://www.uniprot.org/uniprotkb/F6RY68" } ], "common_name": "Bovine", "glygen_name": "Bovine", "reference_species": "Bos taurus [9913]" } ], "gene": [ { "name": "TMEM176B", "url": "https://www.uniprot.org/uniprotkb/F6RY68", "locus": { "chromosome": "4", "start_pos": 113399610, "end_pos": 113408319, "strand": "+", "evidence": [ { "database": "Ensembl Gene", "id": "ENSBTAG00000016766", "url": "https://www.ensembl.org/id/ENSBTAG00000016766" } ] } } ], "crossref": [ { "id": "F6RY68", "url": "https://alphafold.ebi.ac.uk/entry/F6RY68", "database": "AlphaFoldDB", "categories": [] }, { "id": "IPR007237", "url": "https://www.ebi.ac.uk/interpro/entry/IPR007237", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR009281", "url": "https://www.ebi.ac.uk/interpro/entry/IPR009281", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "PTHR15756", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR15756", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR15756:SF7", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR15756:SF7", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF04103", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF04103", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "A0AAA9SGI2", "url": "https://www.uniprot.org/uniprotkb/A0AAA9SGI2", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0AAA9SGI2-1", "url": "https://www.uniprot.org/uniprotkb/A0AAA9SGI2-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "F6RY68", "url": "https://www.uniprot.org/uniprotkb/F6RY68", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "F6RY68-1", "url": "https://www.uniprot.org/uniprotkb/F6RY68-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MAQNTLTVNGVDVGSVLSQPTHIDIHIHQESALAQLLKAGSSLVERLSHRPAKARIGYGQLALGVTQLLLGAISCALGGLLYLGPWIQLRASGCALWAGFVAIAAGVGAIVHEKRRGKLSGCVSGLLTLAGIATAVAAVVFCVNSFIWQYDGFYDISSVCDSLVPVTPTSWYQRRSSYSSWEEENCRRYMQMLMDLFLGIRALLLAICALQVTVSLASLGVGLQSFCGQSSRALDEEGSERNLLGENSVPPSPSKEKTTAVIVL", "length": 264, "header": "tr|F6RY68-1|F6RY68_BOVIN Isoform 1 of Transmembrane protein 176B OS=Bos taurus OX=9913 GN=TMEM176B PE=3 SV=1 CANONICAL=F6RY68-1" }, "isoforms": [ { "isoform_ac": "A0AAA9SGI2-1", "url": "https://www.uniprot.org/uniprotkb/A0AAA9SGI2/entry", "sequence": { "sequence": "MAQNTLTVNGVDVGSVLSQPTHIDIHIHQESALAQLLKAGSSLVERLSHRPAKARIGYGQLALGAIAAGVGAIVHEKRRGKLSGCVSGLLTLAGIATAVAAVVFCVNSFIWQYDGFYDISSVCDSLVPVTPTSWYQRRSSYSSWEEENCRRYMQMLMDLFLGIRALLLAICALQVTVSLASLGVGLQSFCGQSSRALDEEGSERNLLGENSVPPSPSKEKTTAVIVL", "length": 227, "header": "tr|A0AAA9SGI2-1|F6RY68_BOVIN Computationally mapped isoform of Transmembrane protein 176B OS=Bos taurus OX=9913 GN=TMEM176B PE=3 SV=1 CANONICAL=F6RY68-1" }, "locus": { "chromosome": "4", "start_pos": 113405914, "end_pos": 113400614, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000116073.1", "url": "https://www.ensembl.org/id/ENSBTAT00000116073.1" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000081603.1", "url": "https://www.ensembl.org/id/ENSBTAP00000081603.1" } ] } }, { "isoform_ac": "F6RY68-1", "url": "https://www.uniprot.org/uniprotkb/F6RY68/entry", "sequence": { "sequence": "MAQNTLTVNGVDVGSVLSQPTHIDIHIHQESALAQLLKAGSSLVERLSHRPAKARIGYGQLALGVTQLLLGAISCALGGLLYLGPWIQLRASGCALWAGFVAIAAGVGAIVHEKRRGKLSGCVSGLLTLAGIATAVAAVVFCVNSFIWQYDGFYDISSVCDSLVPVTPTSWYQRRSSYSSWEEENCRRYMQMLMDLFLGIRALLLAICALQVTVSLASLGVGLQSFCGQSSRALDEEGSERNLLGENSVPPSPSKEKTTAVIVL", "length": 264, "header": "tr|F6RY68-1|F6RY68_BOVIN Isoform 1 of Transmembrane protein 176B OS=Bos taurus OX=9913 GN=TMEM176B PE=3 SV=1 CANONICAL=F6RY68-1" }, "locus": { "chromosome": "4", "start_pos": 113405914, "end_pos": 113400614, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000043794.4", "url": "https://www.ensembl.org/id/ENSBTAT00000043794.4" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000041338.3", "url": "https://www.ensembl.org/id/ENSBTAP00000041338.3" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [], "orthologs": [], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 1, "go_terms": [ { "name": "membrane", "id": "GO:0016020", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016020", "evidence": [ { "database": "UniProtKB", "id": "F6RY68", "url": "https://www.uniprot.org/uniprotkb/F6RY68" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ], "tool_support": { "graph_view": "yes" } }, { "uniprot_canonical_ac": "G5E584-1", "uniprot_ac": "G5E584", "uniprot_id": "G5E584_BOVIN", "mass": { "chemical_mass": 26240.0, "monoisotopic_mass": 26240.0 }, "refseq": { "ac": "XP_002696834", "name": "transmembrane protein 179 isoform X1", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_002696834" }, "gene_names": [ { "name": "TMEM179", "type": "recommended", "evidence": [ { "id": "G5E584", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G5E584" } ] }, { "name": "TMEM179", "type": "synonym", "evidence": [ { "id": "XP_002696834", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_002696834" } ] } ], "protein_names": [ { "name": "Transmembrane protein 179", "type": "synonym", "evidence": [ { "id": "G5E584", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G5E584/entry#names_and_taxonomy" } ] }, { "name": "transmembrane protein 179 isoform X1", "type": "synonym", "evidence": [ { "id": "XP_002696834", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_002696834" } ] } ], "function": [], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Bos taurus", "taxid": 9913, "evidence": [ { "database": "UniProtKB", "id": "G5E584", "url": "https://www.uniprot.org/uniprotkb/G5E584" } ], "common_name": "Bovine", "glygen_name": "Bovine", "reference_species": "Bos taurus [9913]" } ], "gene": [ { "name": "TMEM179", "url": "https://www.uniprot.org/uniprotkb/G5E584", "locus": { "chromosome": "21", "start_pos": 69069832, "end_pos": 69080040, "strand": "+", "evidence": [ { "database": "Ensembl Gene", "id": "ENSBTAG00000006673", "url": "https://www.ensembl.org/id/ENSBTAG00000006673" } ] } } ], "crossref": [ { "id": "G5E584", "url": "https://alphafold.ebi.ac.uk/entry/G5E584", "database": "AlphaFoldDB", "categories": [] }, { "id": "ENSBTAG00000006673", "url": "https://bgee.org/?page=gene&gene_id=ENSBTAG00000006673", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "536682", "url": "https://www.ncbi.nlm.nih.gov/gene/536682", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR029673", "url": "https://www.ebi.ac.uk/interpro/entry/IPR029673", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR059010", "url": "https://www.ebi.ac.uk/interpro/entry/IPR059010", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "bta:536682", "url": "https://www.genome.jp/dbget-bin/www_bget?bta:536682", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "DEFRGHC", "url": "https://omabrowser.org/oma/group/DEFRGHC/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "G5E584", "url": "https://www.orthodb.org/?gene=G5E584", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR31872", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR31872", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR31872:SF4", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR31872:SF4", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF26158", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF26158", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "XP_002696834", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_002696834", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0AAA9SGV2", "url": "https://www.uniprot.org/uniprotkb/A0AAA9SGV2", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0AAA9SGV2-1", "url": "https://www.uniprot.org/uniprotkb/A0AAA9SGV2-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "G5E584", "url": "https://www.uniprot.org/uniprotkb/G5E584", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "G5E584-1", "url": "https://www.uniprot.org/uniprotkb/G5E584-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MALNNFLFAQCVCYFLAFLFSFVVVVPLSENGHDFRGRCLLFTEGMWLSANLTVQERERFTVQEWGPPAACRFSLLASLLSLLLAAAHAWRTLFFLCKGHEGSFLYAFLNLLVSAFVVFLVFIASTIVSVGFTMWCDTITEKGTVPHSCEELQGIDLELNVDNSAFYDQFAIAQFGLWASWLAWLAITVLAFLKVYHNYRQEDLLDSLVHEKELLLARPAPRAAFQEKSAVI", "length": 232, "header": "tr|G5E584-1|G5E584_BOVIN Isoform 1 of Transmembrane protein 179 OS=Bos taurus OX=9913 GN=TMEM179 PE=3 SV=2 CANONICAL=G5E584-1" }, "isoforms": [ { "isoform_ac": "A0AAA9SGV2-1", "url": "https://www.uniprot.org/uniprotkb/A0AAA9SGV2/entry", "sequence": { "sequence": "MALNNFLFAQCVCYFLAFLFSFVVVVPLSENGHDFRGRCLLFTEGMWLSANLTVQERERFTVQEWGPPAACRFSLLASLLSLLLAAAHAWRTLFFLCKGHEGSFLYAFLNLLVSAFVVFLVFIASTIVSVGFTMWCDTITEKGTVPHSCEELQGIDLELNVDNSAFYDQFAIAQQIKVNLFQRLEEAPLQMKRALLGAEWAQYRPPPWGPHLVRPLGLMAGLAGHHRLGLPESLPQLPPGGPAGQPGP", "length": 248, "header": "tr|A0AAA9SGV2-1|G5E584_BOVIN Computationally mapped isoform of Transmembrane protein 179 OS=Bos taurus OX=9913 GN=TMEM179 PE=3 SV=1 CANONICAL=G5E584-1" }, "locus": { "chromosome": "21", "start_pos": 69079841, "end_pos": 69070369, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000135573.1", "url": "https://www.ensembl.org/id/ENSBTAT00000135573.1" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000083119.1", "url": "https://www.ensembl.org/id/ENSBTAP00000083119.1" } ] } }, { "isoform_ac": "G5E584-1", "url": "https://www.uniprot.org/uniprotkb/G5E584/entry", "sequence": { "sequence": "MALNNFLFAQCVCYFLAFLFSFVVVVPLSENGHDFRGRCLLFTEGMWLSANLTVQERERFTVQEWGPPAACRFSLLASLLSLLLAAAHAWRTLFFLCKGHEGSFLYAFLNLLVSAFVVFLVFIASTIVSVGFTMWCDTITEKGTVPHSCEELQGIDLELNVDNSAFYDQFAIAQFGLWASWLAWLAITVLAFLKVYHNYRQEDLLDSLVHEKELLLARPAPRAAFQEKSAVI", "length": 232, "header": "tr|G5E584-1|G5E584_BOVIN Isoform 1 of Transmembrane protein 179 OS=Bos taurus OX=9913 GN=TMEM179 PE=3 SV=2 CANONICAL=G5E584-1" }, "locus": { "chromosome": "21", "start_pos": 69079841, "end_pos": 69070302, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000008762.6", "url": "https://www.ensembl.org/id/ENSBTAT00000008762.6" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000008762.5", "url": "https://www.ensembl.org/id/ENSBTAP00000008762.5" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [ { "id": "bta:536682", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?bta:536682", "resource": "KEGG Pathway" } ], "orthologs": [ { "uniprot_canonical_ac": "A0A287B4Q1-1", "protein_name": "Transmembrane protein 179", "gene_name": "TMEM179", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MALDNFLFAQCVCYFLAFLFSFVVVVPLSEHGHDFRGRCLLFTEGMWLSANLTVQERERFTVQEWGPPAACRFSLLASLLSLLLAAAHAWRTLFFLCKGHEGSFLHAFLSLLVSAFVLFLVFIASTIVSVGFTMWCDAITEKGTVPHSCEELQDIDLELNVDNSAFYDQFAIAQFGLWASWLAWLAITILAFLKVYHDYRQEDLLDSLTHEKELLLARPTSRGSFQDEKSAVI", "length": 233 }, "evidence": [ { "id": "G5E584", "url": "https://omabrowser.org/oma/group/G5E584/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "A0A8V0Z016-1", "protein_name": "Transmembrane protein 179", "gene_name": "TMEM179", "tax_id": 9031, "organism": "Gallus gallus", "sequence": { "sequence": "MALSNFLFAQCICYFLAFLFSFIVVVPLSENGNDFHGRCLLFTEGMWLNANLTVERQRFTVQEWGPEAACRFSIFTGLLSLLLATVQAWRTLFFLCKGHEDSFFYAFLNLLISAFVVFITFIASTIVSVGFNMWCDAITEKGSMPNSCEELQDIDLELNLENSAFYDQFAVAQFGLWAAWLTWLGITILAFLKVYQNYRQEDLLDSLIHEKELLLGRSSSRTSLQDEKSAMI", "length": 232 }, "evidence": [ { "id": "G5E584", "url": "https://omabrowser.org/oma/group/G5E584/", "database": "OMA" } ], "glygen_name": "Chicken", "common_name": "Chicken" }, { "uniprot_canonical_ac": "E7EYU1-1", "protein_name": "Transmembrane protein 179", "gene_name": "tmem179ab", "tax_id": 7955, "organism": "Danio rerio", "sequence": { "sequence": "MAMDNFIFAQCILYFLAFVFAFIAIVPLSENTEDFRGKCLLFTRGMWQNENITVSKQRFIIEEWGPQSSCSFITAVAIASLILSAVQAWRLLFFICKGHDDSIFNAFLNLLISTFVVFAVFLSSTIVSVGFNLWCDAITEGGSMHSSCEDLQDTDLELGLDNSAFYDQFAIAQFGLWAAWLTWLGITIVAFLKVYHNYRQEDLVDSLIHEKEFLLGRSSRRGSDVVHDKSGMI", "length": 233 }, "evidence": [ { "id": "G5E584", "url": "https://omabrowser.org/oma/group/G5E584/", "database": "OMA" } ], "glygen_name": "Zebrafish", "common_name": "Zebrafish" }, { "uniprot_canonical_ac": "E9PU04-1", "protein_name": "Transmembrane protein 179", "gene_name": "Tmem179", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MALNNFLFAQCVCYFLAFLFSFVVVVPLSENGHDFRGRCLLFTEGMWLSANLTMQGRERFTVQEWGPPAACRFSLLASLLSLLLAAAHAWRTLFFLCKGHEGSFFYAFLNLLVSAFVVFLVFIASTIVSVGFTMWCDTITEKGSAPHSCEEFQETDLELNVDNSAFYHQFAIAQFGLWASWLAWLAITTLAFLKVYHNYRQEDLLDSLVHEKELLLARPASRTSFQGEKSAVI", "length": 233 }, "evidence": [ { "id": "G5E584", "url": "https://omabrowser.org/oma/group/G5E584/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "Q6ZVK1-1", "protein_name": "Transmembrane protein 179", "gene_name": "TMEM179", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MALNNFLFAQCACYFLAFLFSFVVVVPLSENGHDFRGRCLLFTEGMWLSANLTVQERERFTVQEWGPPAACRFSLLASLLSLLLAAAHAWRTLFFLCKGHEGSFFSAFLNLLVSAFVVFLVFIASTIVSVGFTMWCDTITEKGTVPHSCEELQDIDLELGVDNSAFYDQFAIAQFGLWASWLAWLAITTLAFLKVYHNYRQEDLLDSLIHEKELLLARPSPRTSFQEEKSAVI", "length": 233 }, "evidence": [ { "id": "G5E584", "url": "https://omabrowser.org/oma/group/G5E584/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "Q8BHH9-1", "protein_name": "Transmembrane protein 179", "gene_name": "Tmem179", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MALNNFLFAQCVCYFLAFLFSFVVVVPLSENGHDFRGRCLLFTEGMWLSANLTMQGRERFTVQEWGPPAACRFSLLASLLSLLLAAAHAWRTLFFLCKGHEGSFFYAFLNLLVSAFVVFLVFIASTIVSVGFTMWCDTITEKGSTPHSCEEFQETDLELNVDNSAFYHQFAIAQFGLWASWLAWLAITTLAFLKVYHNYRQEDLLDSLVHEKELLLARPTSRTSFQGEKSAVI", "length": 233 }, "evidence": [ { "id": "G5E584", "url": "https://omabrowser.org/oma/group/G5E584/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q9VCF1-1", "protein_name": "Transmembrane protein 179", "gene_name": "Dmel\\CG13603", "tax_id": 7227, "organism": "Drosophila melanogaster", "sequence": { "sequence": "MALANVLQLSQIAGHVILFILSLCIVVPLFINLDQFCGHCLLFTTGKWREEDGMFDVQWASNGFCNFPLITGFFLLIISVVQIYRYARMKEEASFIALFIDVVLGIWMLAMSILSAIFITLGFIVWCDSMTERFPSCAISAGQNIIHGDTEKINTSGFYIEMGTTQFGAWGSFAISVGIAVIALLKLIDNHQVRNIKVSMYLERQRLVNQQQYDGRSTPPIVSNASSDTEQNK", "length": 233 }, "evidence": [ { "id": "G5E584", "url": "https://omabrowser.org/oma/group/G5E584/", "database": "OMA" } ], "glygen_name": "Fruit fly", "common_name": "Fruit fly" } ], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 1, "go_terms": [ { "name": "membrane", "id": "GO:0016020", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016020", "evidence": [ { "database": "UniProtKB", "id": "G5E584", "url": "https://www.uniprot.org/uniprotkb/G5E584" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 51, "end_pos": 53, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" }, { "name": "homologset.oma", "label": "OMA Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 51, "end_pos": 53 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ], "tool_support": { "graph_view": "yes" } }, { "uniprot_canonical_ac": "F6RUM1-1", "uniprot_ac": "F6RUM1", "uniprot_id": "F6RUM1_BOVIN", "mass": { "chemical_mass": 82360.0, "monoisotopic_mass": 82360.0 }, "refseq": {}, "gene_names": [ { "name": "BUD13", "type": "recommended", "evidence": [ { "id": "F6RUM1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F6RUM1" } ] } ], "protein_names": [ { "name": "BUD13 homolog", "type": "recommended", "evidence": [ { "id": "F6RUM1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F6RUM1/entry#names_and_taxonomy" } ] } ], "function": [], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Bos taurus", "taxid": 9913, "evidence": [ { "database": "UniProtKB", "id": "F6RUM1", "url": "https://www.uniprot.org/uniprotkb/F6RUM1" } ], "common_name": "Bovine", "glygen_name": "Bovine", "reference_species": "Bos taurus [9913]" } ], "gene": [ { "name": "BUD13", "url": "https://www.uniprot.org/uniprotkb/F6RUM1", "locus": { "chromosome": "15", "start_pos": 27406282, "end_pos": 27431348, "strand": "+", "evidence": [ { "database": "Ensembl Gene", "id": "ENSBTAG00000016855", "url": "https://www.ensembl.org/id/ENSBTAG00000016855" } ] } } ], "crossref": [ { "id": "F6RUM1", "url": "https://alphafold.ebi.ac.uk/entry/F6RUM1", "database": "AlphaFoldDB", "categories": [] }, { "id": "IPR018609", "url": "https://www.ebi.ac.uk/interpro/entry/IPR018609", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR051112", "url": "https://www.ebi.ac.uk/interpro/entry/IPR051112", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "PTHR31809", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR31809", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR31809:SF0", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR31809:SF0", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF09736", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF09736", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "A0AAA9SKJ6", "url": "https://www.uniprot.org/uniprotkb/A0AAA9SKJ6", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0AAA9SKJ6-1", "url": "https://www.uniprot.org/uniprotkb/A0AAA9SKJ6-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "F6RUM1", "url": "https://www.uniprot.org/uniprotkb/F6RUM1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "F6RUM1-1", "url": "https://www.uniprot.org/uniprotkb/F6RUM1-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MEGRREETQLPGQRGCRVGPGSVRVSVLQSSKILRLAHVCPALPNTPSLPVLAPPPRSSLLFRFAFNNFVPSPDPFPSAAMAAAPPLSKAEYLKRYLSGADGGVDGGPESGRKRRKKRPKPSGAGGKGMRIVDDDVSWTSISTTKAEKEEEEDDGDLPVVAEFVDERPEEVKQMEAFRSSAKWKLLGSHSEDTPSHRQFCHDTPDSSPPRKVRHDTPDPSSPRRVRHDTPDPSPPRRVRHDTPDPSPPRKVRHDTPDSSPPRKARHDTPDSSPPRKIRHDTLDSAPPRKVRHDTPDPSPPRRTRHDTPDSSPPRRTYHSSSDLSPARRARNCSPDTAQPRRTLDSVDRSQLRKAHHNSSDLAANVPHSLPRTKSSEAPESSSKTSPHCKGPGPSHPSLPKNSKYEYDSDLSPSRKKQATSHVGNKQHDSKGSSPTHRKHHTGSPPRKHHTLDSSSYPGDSRKTSDSDLSPPRHKQSSGPQDSDSDLSPPRNRPRHRSSDSDLSPPRRKQRAKSSDSDLSPPRRSQPLGKKAAHMYSGAKTGLVLTDIQREQQELKKRDQETMAFEAEFQHAETVFRDKSGRKRNLKLERLEQRRKAEKDSKREELYAQWGKGLAQTRQQQQNVEDAMKEMQKPLARYIDDEDLDRMLREQEREGDPMANFIKKNKAKENKNKKVRPRYSGPAPPPNRFNIWPGYRWDGVDRSNGFEQKRFARLASKKAVEELAYKWSVEDM", "length": 731, "header": "tr|F6RUM1-1|F6RUM1_BOVIN Isoform 1 of BUD13 homolog OS=Bos taurus OX=9913 GN=BUD13 PE=3 SV=1 CANONICAL=F6RUM1-1" }, "isoforms": [ { "isoform_ac": "A0AAA9SKJ6-1", "url": "https://www.uniprot.org/uniprotkb/A0AAA9SKJ6/entry", "sequence": { "sequence": "MEGRREETQLPGQRGCRVGPGSVRVSVLQSSKILRLAHVCPALPNTPSLPVLAPPPRSSLLFRFAFNNFVPSPDPFPSAAMAAAPPLSKAEYLKRYLSGADGGVDGGPESGRKRRKKRPKPSGAGGKGMRIVDDDVSWTSISTTKAEKEEEEDDGDLPVVAEFVDERPEEVKQMEAFRSSAKWKLLGSHSEDTPSHRQFCHDTPDSSPPRKVRHDTPDPSSPRRVRHDTPDPSPPRRVRHDTPDPSPPRKIRHDTLDSAPPRKVRHDTPDPSPPRRTRHDTPDSSPPRRTYHSSSDLSPARRARNCSPDTAQPRRTLDSVDRSQLRKAHHNSSDLAANVPHSLPRTKSSEAPESSSKTSPHCKGPGPSHPSLPKNSKYEYDSDLSPSRKKQATSHVGNKQHDSKGSSPTHRKHHTGSPPRKHHTLDSSSYPGDSRKTSDSDLSPPRHKQSSGPQDSDSDLSPPRNRPRHRSSDSDLSPPRRKQRAKSSDSDLSPPRRSQPLGKKAAHMYSGAKTGLVLTDIQREQQELKKRDQETMAFEAEFQHAETVFRDKSGRKRNLKLERLEQRRKAEKDSKREELYAQWGKGLAQTRQQQQNVEDAMKEMQKPLARYIDDEDLDRMLREQEREGDPMANFIKKNKAKENKNKKVRPRYSGPAPPPNRFNIWPGYRWDGVDRSNGFEQKRFARLASKKAVEELAYKWSVEDM", "length": 705, "header": "tr|A0AAA9SKJ6-1|F6RUM1_BOVIN Computationally mapped isoform of BUD13 homolog OS=Bos taurus OX=9913 GN=BUD13 PE=3 SV=1 CANONICAL=F6RUM1-1" }, "locus": { "chromosome": "15", "start_pos": 27431149, "end_pos": 27406591, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000129906.1", "url": "https://www.ensembl.org/id/ENSBTAT00000129906.1" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000083142.1", "url": "https://www.ensembl.org/id/ENSBTAP00000083142.1" } ] } }, { "isoform_ac": "F6RUM1-1", "url": "https://www.uniprot.org/uniprotkb/F6RUM1/entry", "sequence": { "sequence": "MEGRREETQLPGQRGCRVGPGSVRVSVLQSSKILRLAHVCPALPNTPSLPVLAPPPRSSLLFRFAFNNFVPSPDPFPSAAMAAAPPLSKAEYLKRYLSGADGGVDGGPESGRKRRKKRPKPSGAGGKGMRIVDDDVSWTSISTTKAEKEEEEDDGDLPVVAEFVDERPEEVKQMEAFRSSAKWKLLGSHSEDTPSHRQFCHDTPDSSPPRKVRHDTPDPSSPRRVRHDTPDPSPPRRVRHDTPDPSPPRKVRHDTPDSSPPRKARHDTPDSSPPRKIRHDTLDSAPPRKVRHDTPDPSPPRRTRHDTPDSSPPRRTYHSSSDLSPARRARNCSPDTAQPRRTLDSVDRSQLRKAHHNSSDLAANVPHSLPRTKSSEAPESSSKTSPHCKGPGPSHPSLPKNSKYEYDSDLSPSRKKQATSHVGNKQHDSKGSSPTHRKHHTGSPPRKHHTLDSSSYPGDSRKTSDSDLSPPRHKQSSGPQDSDSDLSPPRNRPRHRSSDSDLSPPRRKQRAKSSDSDLSPPRRSQPLGKKAAHMYSGAKTGLVLTDIQREQQELKKRDQETMAFEAEFQHAETVFRDKSGRKRNLKLERLEQRRKAEKDSKREELYAQWGKGLAQTRQQQQNVEDAMKEMQKPLARYIDDEDLDRMLREQEREGDPMANFIKKNKAKENKNKKVRPRYSGPAPPPNRFNIWPGYRWDGVDRSNGFEQKRFARLASKKAVEELAYKWSVEDM", "length": 731, "header": "tr|F6RUM1-1|F6RUM1_BOVIN Isoform 1 of BUD13 homolog OS=Bos taurus OX=9913 GN=BUD13 PE=3 SV=1 CANONICAL=F6RUM1-1" }, "locus": { "chromosome": "15", "start_pos": 27431149, "end_pos": 27406591, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000022419.6", "url": "https://www.ensembl.org/id/ENSBTAT00000022419.6" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000022419.5", "url": "https://www.ensembl.org/id/ENSBTAP00000022419.5" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [], "orthologs": [], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 2, "go_terms": [ { "name": "nucleoplasm", "id": "GO:0005654", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005654", "evidence": [ { "database": "UniProtKB", "id": "F6RUM1", "url": "https://www.uniprot.org/uniprotkb/F6RUM1" } ], "pmid": "" }, { "name": "U2-type precatalytic spliceosome", "id": "GO:0071005", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0071005", "evidence": [ { "database": "UniProtKB", "id": "F6RUM1", "url": "https://www.uniprot.org/uniprotkb/F6RUM1" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 1, "go_terms": [ { "name": "mRNA splicing, via spliceosome", "id": "GO:0000398", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000398", "evidence": [ { "database": "UniProtKB", "id": "F6RUM1", "url": "https://www.uniprot.org/uniprotkb/F6RUM1" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 331, "end_pos": 333, "annotation": "n_glycosylation_sequon" }, { "start_pos": 357, "end_pos": 359, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 331, "end_pos": 333 }, { "start_pos": 357, "end_pos": 359 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", 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"table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ], "tool_support": { "graph_view": "yes" } }, { "uniprot_canonical_ac": "F6RPG2-1", "uniprot_ac": "F6RPG2", "uniprot_id": "F6RPG2_BOVIN", "mass": { "chemical_mass": 71245.0, "monoisotopic_mass": 71245.0 }, "refseq": { "ac": "XP_005219052", "name": "zinc finger protein 527 isoform X1", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_005219052" }, "gene_names": [ { "name": "ZNF527", "type": "recommended", "evidence": [ { "id": "F6RPG2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F6RPG2" } ] }, { "name": "ZNF527", "type": "synonym", "evidence": [ { "id": "XP_005219052", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_005219052" } ] } ], "protein_names": [ { "name": "Zinc finger protein 527", "type": "synonym", "evidence": [ { "id": "F6RPG2", "database": "UniProtKB", "url": 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{ "id": "PTHR24384", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR24384", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR24384:SF247", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR24384:SF247", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00096", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00096", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF01352", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF01352", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF13465", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF13465", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "XP_005219052", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_005219052", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0AAA9SMH9", "url": 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"MAVGLCKAMSQGLVTFRDVALNFSQEEWEWLDSSQKDLYRDVMLENYRNLVWLGLSISKPNMISLLEQGKEPWMVEREMSDGQHADWESWYEIKALSPKWYTDEEEISQGVITKRLTSYSLEFSSFREAWKYEAEFERHQGNQERHFRQVATLKEISAVKKDSEYNNSERNILLKSVLLTQQRVPPVEQVHKFGIFNKMFPPNSVLIEHKRLHAEKESLIGNECEEFNQSTYLSKDVEISPGEKSYESNDFSNLLSFHSLLTQHQATHFGKSPRGYDEYGNAFSCYSYFSQPQRIHNREKPYACNDCGKGFSHDFFLSEHQRTHIGEKPYECKECNKAFRQSAHLAQHQRIHTGEKPFACNECGKAFSRYAFLVEHQRIHTGEKPYECKECNKAFRQSAHLNQHQRIHTGEKPYECNQCGKAFSRRIALTLHQRIHTGEKPFKCNECGKTFGYRSHLNQHQRIHTGEKPYECIKCGKFFRTDSQLNRHHRIHTGERPFECNKCGKAFSDALVLIHHKRSHAGEKPYECNKCGKAFSCGSYLNQHQRIHTGEKPYECNECGKAFHQVLSLRLHQRIHAGEKPYNCNECGNNFSRASTLRRHQKIHNRKIL", "length": 609, "header": "tr|F6RPG2-1|F6RPG2_BOVIN Isoform 1 of Zinc finger protein 527 OS=Bos taurus OX=9913 GN=ZNF527 PE=3 SV=2 CANONICAL=F6RPG2-1" }, "isoforms": [ { "isoform_ac": "A0AAA9SMH9-1", "url": "https://www.uniprot.org/uniprotkb/A0AAA9SMH9/entry", "sequence": { "sequence": 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"database": "Ensembl Peptide", "id": "ENSBTAP00000083968.2", "url": "https://www.ensembl.org/id/ENSBTAP00000083968.2" } ] } }, { "isoform_ac": "F6RPG2-1", "url": "https://www.uniprot.org/uniprotkb/F6RPG2/entry", "sequence": { "sequence": "MAVGLCKAMSQGLVTFRDVALNFSQEEWEWLDSSQKDLYRDVMLENYRNLVWLGLSISKPNMISLLEQGKEPWMVEREMSDGQHADWESWYEIKALSPKWYTDEEEISQGVITKRLTSYSLEFSSFREAWKYEAEFERHQGNQERHFRQVATLKEISAVKKDSEYNNSERNILLKSVLLTQQRVPPVEQVHKFGIFNKMFPPNSVLIEHKRLHAEKESLIGNECEEFNQSTYLSKDVEISPGEKSYESNDFSNLLSFHSLLTQHQATHFGKSPRGYDEYGNAFSCYSYFSQPQRIHNREKPYACNDCGKGFSHDFFLSEHQRTHIGEKPYECKECNKAFRQSAHLAQHQRIHTGEKPFACNECGKAFSRYAFLVEHQRIHTGEKPYECKECNKAFRQSAHLNQHQRIHTGEKPYECNQCGKAFSRRIALTLHQRIHTGEKPFKCNECGKTFGYRSHLNQHQRIHTGEKPYECIKCGKFFRTDSQLNRHHRIHTGERPFECNKCGKAFSDALVLIHHKRSHAGEKPYECNKCGKAFSCGSYLNQHQRIHTGEKPYECNECGKAFHQVLSLRLHQRIHAGEKPYNCNECGNNFSRASTLRRHQKIHNRKIL", "length": 609, "header": "tr|F6RPG2-1|F6RPG2_BOVIN Isoform 1 of Zinc finger protein 527 OS=Bos taurus OX=9913 GN=ZNF527 PE=3 SV=2 CANONICAL=F6RPG2-1" }, "locus": { "chromosome": "18", "start_pos": 47392381, "end_pos": 47384236, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000053874.4", "url": "https://www.ensembl.org/id/ENSBTAT00000053874.4" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000049121.3", "url": "https://www.ensembl.org/id/ENSBTAP00000049121.3" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [ { "id": "bta:538845", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?bta:538845", "resource": "KEGG Pathway" } ], "orthologs": [], "go_annotation": { "categories": [ { "name": "Molecular Function", "total": 2, "go_terms": [ { "name": "zinc ion binding", "id": "GO:0008270", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008270", "evidence": [ { "database": "UniProtKB", "id": "F6RPG2", "url": "https://www.uniprot.org/uniprotkb/F6RPG2" } ], "pmid": "" }, { "name": "DNA binding", "id": "GO:0003677", "url": 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This stimulates cell separation at the base of forming clefts by local, dynamic intercellular gap formation and promotes cleft progression.", "evidence": [ { "database": "UniProtKB", "id": "G3X8E7", "url": "https://www.uniprot.org/uniprotkb/G3X8E7#function" }, { "database": "UniProtKB", "id": "ARBA00056723", "url": "https://www.uniprot.org/uniprotkb/ARBA00056723#function" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Bos taurus", "taxid": 9913, "evidence": [ { "database": "UniProtKB", "id": "G3X8E7", "url": "https://www.uniprot.org/uniprotkb/G3X8E7" } ], "common_name": "Bovine", "glygen_name": "Bovine", "reference_species": "Bos taurus [9913]" } ], "gene": [ { "name": "BTBD7", "url": "https://www.uniprot.org/uniprotkb/G3X8E7", "locus": { "chromosome": "21", "start_pos": 57861432, "end_pos": 57947106, "strand": "+", "evidence": [ { "database": "Ensembl Gene", "id": "ENSBTAG00000046185", "url": "https://www.ensembl.org/id/ENSBTAG00000046185" } ] } } ], "crossref": [ { "id": "G3X8E7", "url": "https://alphafold.ebi.ac.uk/entry/G3X8E7", "database": "AlphaFoldDB", "categories": [] }, { "id": "ENSBTAG00000046185", "url": "https://bgee.org/?page=gene&gene_id=ENSBTAG00000046185", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "cd18283", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd18283", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "cd18284", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd18284", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "cd18489", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd18489", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "100300409", "url": "https://www.ncbi.nlm.nih.gov/gene/100300409", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR000210", "url": "https://www.ebi.ac.uk/interpro/entry/IPR000210", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR011333", "url": "https://www.ebi.ac.uk/interpro/entry/IPR011333", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR011705", "url": "https://www.ebi.ac.uk/interpro/entry/IPR011705", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR042345", "url": "https://www.ebi.ac.uk/interpro/entry/IPR042345", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR047934", "url": "https://www.ebi.ac.uk/interpro/entry/IPR047934", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR047935", "url": "https://www.ebi.ac.uk/interpro/entry/IPR047935", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR047936", "url": "https://www.ebi.ac.uk/interpro/entry/IPR047936", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "bta:100300409", "url": "https://www.genome.jp/dbget-bin/www_bget?bta:100300409", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "ILMKFHR", "url": "https://omabrowser.org/oma/group/ILMKFHR/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "G3X8E7", "url": "https://www.orthodb.org/?gene=G3X8E7", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR16064", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR16064", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR16064:SF3", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR16064:SF3", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00651", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00651", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF07707", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF07707", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "XP_010815608", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_010815608", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0AAA9SNK4", "url": "https://www.uniprot.org/uniprotkb/A0AAA9SNK4", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0AAA9SNK4-1", "url": "https://www.uniprot.org/uniprotkb/A0AAA9SNK4-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "G3X8E7", "url": "https://www.uniprot.org/uniprotkb/G3X8E7", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "G3X8E7-1", "url": "https://www.uniprot.org/uniprotkb/G3X8E7-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MGANASSYPHSCSPRVGGNPQAQQTFIGTSSYSQQGYGCESKLYSLDHGHEKPQDKKKRTSGLATLKKKFIKRRKSNRSADHAKQMRELLSGWDVRDVNALVEEYEGTSALKELSLQASVARPEARTLQKDMADLYEYKYCTDVDLIFQETCFPVHRAILAARCPFFKTLLSSSPEYGAEIIMDINTAGIDMPMFSALLHYLYTGEFGMEDSRFQNVDILVQLREEFGTPNSLDVDMRGLFDYMCYYDVVLSFSSDSELVEAFGGNQNCLDEELKAHKAIISARSPFFRNLLQRRIRTGEEITDRTLRTPTRIILDESIIPKKYAKVILHCMYTDMVDLAVLHCSPSVGSLSEVQALVAGKPNMTRAEEAMELYHIALFLEFNMLAQGCEDIIAESISLDTLIAILKWSSHPYGSKWVHRQALHFLCEEFSQVMTSDVFYELSKDHLLTAIQSDYLQASEQDILKYLIKWGEHQLMKRIADREPNLLSGTAHSVNKRGVKRRDLDIEELREILSSLLPFVRIEHILPINSEVLSDAMKRGLISTPPSDMLPTTEGGKSNAWLRQKNAGIYVRPRLFSPYVEEAKSVLDEMMVEQTDLVRLRMVRMSNVPDTLYMVSNAVPQCCHMISHQQISSNQSSPPSVVANEIPVPRLLIMKDMVRRLQELRHTEQVQRAYALNCGEGATVSYEIQIRVLREFGLADAAAELLQNPHKFFPDERFGDESPLLTMRQSGRCRVNSTPTAETMFTDLDSFVAFHPPLPPPPPPYHPPATPIHNQLKAGWKQRPPSQHPSRSFSYPCNHSLFHSRTAPKAGPPPVYLPGVKAAAPDCTNTTGLGRQTVAAAAAAASTTIASEKQVCTQPVLNDLMPDIAMGVSTLSLKDRRLPELAVDTELSQAVSEVGPGPPQHLSCIPQRHTHTSRKKHTLEQKTDARENQQEYPDFYDFSNAACRPSAPAPGRRTPSPSQGGYFGPDLYSHNKASPSGLKSAYLPGQTSPKKQEETRKEYPLPPDGHPHRQKSEPIHLDVVEQPPQRPDFPLAAPENAGSGSAHVRGRAAVETDLTFGLTPNRPSHSACSSEAPEERSGRRLADESLGHGAQRNTDLEREDSVSRGRRSPSKPDFLYKKSAL", "length": 1125, "header": "tr|G3X8E7-1|G3X8E7_BOVIN Isoform 1 of BTB/POZ domain-containing protein 7 OS=Bos taurus OX=9913 GN=BTBD7 PE=4 SV=1 CANONICAL=G3X8E7-1" }, "isoforms": [ { "isoform_ac": "A0AAA9SNK4-1", "url": "https://www.uniprot.org/uniprotkb/A0AAA9SNK4/entry", "sequence": { "sequence": "MARGAGAGADGGAGGGGGGGDGRGPSGGSSSGRRSLRGCEDIIAESISLDTLIAILKWSSHPYGSKWVHRQALHFLCEEFSQVMTSDVFYELSKDHLLTAIQSDYLQASEQDILKYLIKWGEHQLMKRIADREPNLLSGTAHSVNKRGVKRRDLDIEELREILSSLLPFVRIEHILPINSEVLSDAMKRGLISTPPSDMLPTTEGGKSNAWLRQKNAGIYVRPRLFSPYVEEAKSVLDEMMVEQTDLVRLRMVRMSNVPDTLYMVSNAVPQCCHMISHQQISSNQSSPPSVVANEIPVPRLLIMKDMVRRLQELRHTEQVQRAYALNCGEGATVSYEIQIRVLREFGLADAAAELLQNPHKFFPDERFGDESPLLTMRQSGRCRVNSTPTAETMFTDLDSFVAFHPPLPPPPPPYHPPATPIHNQLKAGWKQRPPSQHPSRSFSYPCNHSLFHSRTAPKAGPPPVYLPGVKAAAPDCTNTTGLGRQTVAAAAAAASTTIASEKQVCTQPVLNDLMPDIAMGVSTLSLKDRRLPELAVDTELSQAVSEVGPGPPQHLSCIPQRHTHTSRKKHTLEQKTDARENQQEYPDFYDFSNAACRPSAPAPGRRTPSPSQGGYFGPDLYSHNKASPSGLKSAYLPGQTSPKKQEETRKEYPLPPDGHPHRQKSEPIHLDVVEQPPQRPDFPLAAPENAGSGSAHVRGRAAVETDLTFGLTPNRPSHSACSSEAPEERSGRRLADESLGHGAQRNTDLEREDSVSRGRRSPSKPDFLYKKSAL", "length": 775, "header": "tr|A0AAA9SNK4-1|G3X8E7_BOVIN Computationally mapped isoform of BTB/POZ domain-containing protein 7 OS=Bos taurus OX=9913 GN=BTBD7 PE=4 SV=1 CANONICAL=G3X8E7-1" }, "locus": { "chromosome": "21", "start_pos": 57946907, "end_pos": 57862436, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000124028.1", "url": "https://www.ensembl.org/id/ENSBTAT00000124028.1" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000085542.1", "url": "https://www.ensembl.org/id/ENSBTAP00000085542.1" } ] } }, { "isoform_ac": "G3X8E7-1", "url": "https://www.uniprot.org/uniprotkb/G3X8E7/entry", "sequence": { "sequence": "MGANASSYPHSCSPRVGGNPQAQQTFIGTSSYSQQGYGCESKLYSLDHGHEKPQDKKKRTSGLATLKKKFIKRRKSNRSADHAKQMRELLSGWDVRDVNALVEEYEGTSALKELSLQASVARPEARTLQKDMADLYEYKYCTDVDLIFQETCFPVHRAILAARCPFFKTLLSSSPEYGAEIIMDINTAGIDMPMFSALLHYLYTGEFGMEDSRFQNVDILVQLREEFGTPNSLDVDMRGLFDYMCYYDVVLSFSSDSELVEAFGGNQNCLDEELKAHKAIISARSPFFRNLLQRRIRTGEEITDRTLRTPTRIILDESIIPKKYAKVILHCMYTDMVDLAVLHCSPSVGSLSEVQALVAGKPNMTRAEEAMELYHIALFLEFNMLAQGCEDIIAESISLDTLIAILKWSSHPYGSKWVHRQALHFLCEEFSQVMTSDVFYELSKDHLLTAIQSDYLQASEQDILKYLIKWGEHQLMKRIADREPNLLSGTAHSVNKRGVKRRDLDIEELREILSSLLPFVRIEHILPINSEVLSDAMKRGLISTPPSDMLPTTEGGKSNAWLRQKNAGIYVRPRLFSPYVEEAKSVLDEMMVEQTDLVRLRMVRMSNVPDTLYMVSNAVPQCCHMISHQQISSNQSSPPSVVANEIPVPRLLIMKDMVRRLQELRHTEQVQRAYALNCGEGATVSYEIQIRVLREFGLADAAAELLQNPHKFFPDERFGDESPLLTMRQSGRCRVNSTPTAETMFTDLDSFVAFHPPLPPPPPPYHPPATPIHNQLKAGWKQRPPSQHPSRSFSYPCNHSLFHSRTAPKAGPPPVYLPGVKAAAPDCTNTTGLGRQTVAAAAAAASTTIASEKQVCTQPVLNDLMPDIAMGVSTLSLKDRRLPELAVDTELSQAVSEVGPGPPQHLSCIPQRHTHTSRKKHTLEQKTDARENQQEYPDFYDFSNAACRPSAPAPGRRTPSPSQGGYFGPDLYSHNKASPSGLKSAYLPGQTSPKKQEETRKEYPLPPDGHPHRQKSEPIHLDVVEQPPQRPDFPLAAPENAGSGSAHVRGRAAVETDLTFGLTPNRPSHSACSSEAPEERSGRRLADESLGHGAQRNTDLEREDSVSRGRRSPSKPDFLYKKSAL", "length": 1125, "header": "tr|G3X8E7-1|G3X8E7_BOVIN Isoform 1 of BTB/POZ domain-containing protein 7 OS=Bos taurus OX=9913 GN=BTBD7 PE=4 SV=1 CANONICAL=G3X8E7-1" }, "locus": { "chromosome": "21", "start_pos": 57914968, "end_pos": 57862436, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000063586.3", "url": "https://www.ensembl.org/id/ENSBTAT00000063586.3" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000055665.1", "url": "https://www.ensembl.org/id/ENSBTAP00000055665.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [ { "id": "bta:100300409", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?bta:100300409", "resource": "KEGG Pathway" } ], "orthologs": [ { "uniprot_canonical_ac": "A0A0G2K9E3-1", "protein_name": "BTB/POZ domain-containing protein 7", "gene_name": "Btbd7", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MGANASNYPHSCSPRVGGNSQAQQTFIGTSSYSQQGYGCESKLYSLDHGHEKPQDKKKRTSGLATLKKKFIKRRKSNRSADHAKQMRELLSGWDVRDVNALVEEYEGTSALKELSLQASLARPEARTLQKDMADLYEYKYCTDVDLIFQETCFPVHRAILAARCPFFKTLLSSSPEYGAEIIMDISTAGIDMPMFSALLHYLYTGEFGMEDSRFQNVDILVQLSEEFGTPNSLDVDMRGLFDYMCYYDVVLSFSSDSELVEAFGGNQNCLDEELKAHKAIISARSPFFRNLLQRRIRTGEEITDRTLRTPTRIILDESIIPKKYAKVILHCMYTDVVDLSVLHCSPSVGSLSEVQALVAGKPNMTRAEEAMELYHIALFLEFNMLAQGCEDIIAESISLETLIAILKWSSHPYGSKWVHRQALHFLCEELSQVMTSDVFYELSKDHLLTAIQSDYLQASEQDILKYLIKWGEHQLMKRIADREPNLLSGTAHSVNKRGVKRRDLDMEELREILSSLLPFVRIEHILPMNSEVLSDAMKRGLISTPPSDMLPTTEGGKSNAWLRQKNAGIYVRPRLFSPYVEEAKSVLDEMMVEQTDLVRLRMVRMSNVPDTLYMVSNAMPQCCHMISHQQISSNQSSPPSVVANEIPVPRLLIMKDMVRRLQELRHTEQVQRAYALNCGEGATVSYEIQIRVLREFGLADAAAELLQNPHKFFPDERFGDESPLLTMRQPGRCRVNSTPTAETMFTDLDSFVAFHPPLPPPPPPYHPPATPIHNQLKAGWKQRPPSHHPSRSFSYPCNHSLFHSRTAPKPGPPPVYLPGVKVAPPDCTNTTALGRQTVAAAAAAAAASAAVISEKQVCPQPVLNDLMPDIAMGVSTLSLKDRRLPELAADTELCQTVSEAGPGPPQHLSCIPQRHTHTSRKKHTLEQKPDGRESQQEYPDLYDFPNAACRPSTPAPGRRTPSPSRGRYFGPDLYSHNKASPNGLKSAYLPGQTSPKKQEDTRREYPLSPDGHPHKQKNEPIRLDVVEQPPQRPDFPSAASENASNGPAHVRARTAVETDLTFGLTPNRPPSHSACSSEVLEERSSRRLTDSESLGHGAQRNADLERDDSISRGRRSPSKPDFLYKKSAL", "length": 1129 }, "evidence": [ { "id": "G3X8E7", "url": "https://omabrowser.org/oma/group/G3X8E7/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "F1SD53-1", "protein_name": "BTB/POZ domain-containing protein 7", "gene_name": "BTBD7", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MGANASNYPHACSPRVGGSSQAQQTFIGTSSFSQQGYGCESKLYSLDHGHEKPQDKKKRTSGLATLKKKFIKRRKSNRSADHAKQMRELLSGWDVRDVNALVEEYEGTSALKELSLQASLARPEARTLQKDMADLYEYKYCTDVDLIFQETCFPVHRAILAARCPFFKTLLSSSPEYGAEIIMDINTAGIDMPMFSALLHYLYTGEFGMEDSRFQNVDILVQLSEEFGTPNSLDVDMRGLFEYMCYYDVVLSFSSDSELVEAFGGNQNCLDEELKAHKAIISARSPFFRNLLQRRIRTGEEITDRTLRTPTRIILDESIIPKKYAKVILHCMYTDIVDLSVLHCSPSVGSLSEVQALVAGKPNMTRAEEAMELYHIALFLEFNMLAQGCEDIIAESISLDTLIAILKWSSHPYGSKWVHRQALHFLCEEFSQVMTSDVFYELSKDHLLTAIQSDYLQASEQDILKYLIKWGEHQLMKRIADREPNLLSGTAHSVNKRGVKRRDLDIEELREILSSLLPFVRIEHILPINSEILSDAMKRGLISTPPSDMLPTTESGKSNAWLRQKNAGIYVRPRLFSPYVEEAKSVLDEMMVEQTDLVRLRMVRMSNVPDTLYMVSNAVPQCCHMISHQQISSNQSSPPSVVANEIPVPRLLIMKDMVRRLQELRHTEQVQRAYALNCGEGATVSYEIQIRVLREFGLADAAAELLQNPHKFFPDERFGDESPLMTVRQSGRCRVNSTPTAETMFTDLDSFVAFHPPLPPPPPPYHPPATPIHNQLKAGWKQRPPSQHPSRSFSYPCNHSLFHSRTAPKAGAPPVYLPGVKAAAPDCTNTTALGRQTVAAAAAATSTAIASEKQVCTQPVLNDLMPDIAMGVSTLSLKDRRLPELAVDTELSQSVSEVGPGPPQHLSCIPQRHTHTSRKKHTLEQKTDAQENQQEYPDFYDFSNAACRPSTPAPGRCTPSPSQGGYFGPDLYSHNKASPSGLKSAYLPGQTSPKKQEEARREYPLSPDGHLHKQKNEPIHLDVVEQPPQRSDFALAAPENAGNGPAHVRGRTAVETDLTFGLTPNRPSHSACSSEAPEERSGRRLADSESLGHGAQRNTDLEREDSISRGRRSPSKPDFLYKKSAL", "length": 1126 }, "evidence": [ { "id": "G3X8E7", "url": "https://omabrowser.org/oma/group/G3X8E7/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "Q5TZA6-1", "protein_name": "BTB/POZ domain-containing protein 7", "gene_name": "btbd7", "tax_id": 7955, "organism": "Danio rerio", "sequence": { "sequence": "MGVNASSYPHSCSPRFGGNPQTQQTFIGASYAPQGYGGESKLYSLEHGPEKPQDKKKKSSGLATLKRRFIKRRKSSRSADHARQMRELLSGWDVRDVNALVEEYEGTAALKELSLQAGLARPEARTLQRDLATLYQHKYCTDVDLIFQDSCFPAHRAILATRCPFFKTLLSSSPGYGAEVLLDVGTAGMDAPMFSSLLHYLYTGELGSDDARLQNVDVLVRLSEEFGTPNSLEADMRNLCEHMPYFDSLLSFSSDSELVEAFGAGGPAPSSMGSGNIGASHGSPDEELRAHKAVLSARSPFFRNLLQRRIRSGEEITERTLHTPTRIILDESIIPKKYARVVLHCMYTDAVDLSLVLRGSPSEGSLGEVQALVAGRGCMSRAEEAMELYHIALFLEFSMLAQGCEDIVADSISLDSVVAILKWSSQPYGSKWVHRQAMHFLCEEFSQVMTSDVLYELSKEHLLAAIQSDYLQASEQDILKYVVKWGEHQLIKRMADREPNLLSGTAHSVNKRGVKRRDLDLEELKEILSPLLPFVRTEHILPANSEVLSDTMKRGLISTPPSDMLPTAEGGKANAWLRQKSAGIYVRPRLFSPYVEEAKAVLEEMMVEQTDLVRLRMVRMSNVPDTLYMVNNAVPQCCHMINHQQMAGSQSAPPSVVANEIPVPRLAVVKEMIRRLQELRHTDQVQRAFALNCGEGATVSYELQIRVLREFGLPDGAAELLQNPHKFFPEERFGDESPVLALRQSGRCRVNSTPAVESMFTDLEALVGFHPPLPPPPPPYHPPTTPGHGQQQFKAGWRPRVPSQPPSRSFSYPCNHALLHRQASSKMGSPVYPPGAKPLPPDCTNAQGGRNLHPDKQMNMEPVINEFMPDIAMGVSAMTLKERRLPEVSMEVESHEPSHPHLSTAPPMSHSYSNRHPHSSRKRHAAEPKPEGPQPDFPDLYEFPGRHVPPYSGPDLYIHGRQAGGGAPPPSYSEASESLRLDVLEQPPQRLDLAIVSQGSVVQAIQRPRPINETDLTCGLGPSTEQYEEWPTGRRPPPEGIGLGLGANVGTGDEGGLGARDRRSPNKPEYPYRKSAL", "length": 1077 }, "evidence": [ { "id": "G3X8E7", "url": "https://omabrowser.org/oma/group/G3X8E7/", "database": "OMA" } ], "glygen_name": "Zebrafish", "common_name": "Zebrafish" }, { "uniprot_canonical_ac": "Q8CFE5-1", "protein_name": "BTB/POZ domain-containing protein 7", "gene_name": "Btbd7", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MGANASNYPHSCSPRVGGNSQAQQTFIGTSSYSQQGYGCESKLYSLDHGHEKPQDKKKRTSGLATLKKKFIKRRKSNRSADHAKQMRELLSGWDVRDVNALVEEYEGTSALKELSLQASLARPEARTLQKDMADLYEDKYCTDVDLIFQETCFPVHRAILAARCPFFKTLLSSSPEYGAEIIMDISTAGIDMPMFSALLHYLYTGEFGMEDSRFQNVDILVQLSEEFGTPNPLDVDMRGLFDYMCYYDVVLSFSSDSELVEAFGGNQNCLDEELKAHKAIISARSPFFRNLLQRRIRTGEEITDRTLRTPTRIILDESIIPKKYAKVILHCMYTDVVDLSVLHCSPSVGSLSEVQALVAGKPNMTRAEEAMELYHIALFLEFNMLAQGCEDIIAESISLDTLIAVLKWSSHPYGSKWVHRQAVHFLCEELSQVMTSDVFYELSKDHLLTAIQSDYLQASEQDILKYLIKWGEHQLMKRIADREPNLLSGTAHSVNKRGVKRRDLDIEELREILSSLLPFVRIEHILPINSEVLSDAMKRGLISTPPSDMLPTAEGGKSNAWLRQKNAGIYVRPRLFSPYVEEAKSVLDEMMVEQTDLVRLRMVRMSNVPDTLYMVSNAMPQCCHMISHQQISSNQSSPPSVVANEIPVPRLLIMKDMVRRLQELRHTEQVQRAYALNCGEGATVSYEIQIRVLREFGLADAAAELLQNPHKFFPDERFGDESPLLTMRQPGRCRVNSTPTAETMFTDLDSFVAFHPPLPPPPPPYHPPATPIHNQLKAGWKQRPPSHHPSRSFSYPCNHSLFHCRTAPKPGPPPVYLPGVKVAPPDCTNTTGLGRQTVAAAAAAAAASAAIIPEKQVCPQPVLNDLMPDIAMGVSTLSLKDRRLPELAADTELCQTVSEAGTGPPQHLSCIPQRHTNTSRKKPTLEQKADGRENQQEYPDLYDFSNAACRPSTPAPGRHSPSPAHGRYFGPDLYSHNKASPNGLKSVYLPGQTSPKKQEDPRREYPPSPDGHPHRQKREPIRLDVVEQPPQRPDFPSAASENASHGPAHVRARTAVETDLTFGLTSNRPPSHSACSSEVLEERSSRRLTDSEPLGHGAHQRNADLERGDSISRGRRSPSKPDFLYKKSAL", "length": 1130 }, "evidence": [ { "id": "G3X8E7", "url": "https://omabrowser.org/oma/group/G3X8E7/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q9P203-1", "protein_name": "BTB/POZ domain-containing protein 7", "gene_name": "BTBD7", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MGANASNYPHSCSPRVGGNSQAQQTFIGTSSYSQQGYGCESKLYSLDHGHEKPQDKKKRTSGLATLKKKFIKRRKSNRSADHAKQMRELLSGWDVRDVNALVEEYEGTSALKELSLQASLARPEARTLQKDMADLYEYKYCTDVDLIFQETCFPVHRAILAARCPFFKTLLSSSPEYGAEIIMDINTAGIDMPMFSALLHYLYTGEFGMEDSRFQNVDILVQLSEEFGTPNSLDVDMRGLFDYMCYYDVVLSFSSDSELVEAFGGNQNCLDEELKAHKAVISARSPFFRNLLQRRIRTGEEITDRTLRTPTRIILDESIIPKKYATVILHCMYTDVVDLSVLHCSPSVGSLSEVQALVAGKPNMTRAEEAMELYHIALFLEFNMLAQGCEDIIAESISLDTLIAILKWSSHPYGSKWVHRQALHFLCEEFSQVMTSDVFYELSKDHLLTAIQSDYLQASEQDILKYLIKWGEHQLMKRIADREPNLLSGTAHSVNKRGVKRRDLDMEELREILSSLLPFVRIEHILPINSEVLSDAMKRGLISTPPSDMLPTTEGGKSNAWLRQKNAGIYVRPRLFSPYVEEAKSVLDEMMVEQTDLVRLRMVRMSNVPDTLYMVNNAVPQCCHMISHQQISSNQSSPPSVVANEIPVPRLLIMKDMVRRLQELRHTEQVQRAYALNCGEGATVSYEIQIRVLREFGLADAAAELLQNPHKFFPDERFGDESPLLTMRQPGRCRVNSTPPAETMFTDLDSFVAFHPPLPPPPPPYHPPATPIHNQLKAGWKQRPPSQHPSRSFSYPCNHSLFHSRTAPKAGPPPVYLPSVKAAPPDCTSTAGLGRQTVAAAAATTTSTATAAAAAASEKQVRTQPVLNDLMPDIAVGVSTLSLKDRRLPELAVDTELSQSVSEAGPGPPQHLSCIPQRHTHTSRKKHTLEQKTDTRENPQEYPDFYDFSNAACRPSTPALSRRTPSPSQGGYFGPDLYSHNKASPSGLKSAYLPGQTSPKKQEEARREYPLSPDGHLHRQKNEPIHLDVVEQPPQRSDFPLAAPENASTGPAHVRGRTAVETDLTFGLTPNRPSLSACSSEAPEERSGRRLADSESLGHGAQRNTDLEREDSISRGRRSPSKPDFLYKKSAL", 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"end_pos": 4259427, "strand": "-", "evidence": [ { "database": "Ensembl Gene", "id": "ENSBTAG00000034827", "url": "https://www.ensembl.org/id/ENSBTAG00000034827" } ] } } ], "crossref": [ { "id": "F6RXK0", "url": "https://alphafold.ebi.ac.uk/entry/F6RXK0", "database": "AlphaFoldDB", "categories": [] }, { "id": "ENSBTAG00000034827", "url": "https://bgee.org/?page=gene&gene_id=ENSBTAG00000034827", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "cd00041", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd00041", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "cd00135", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd00135", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "525931", "url": "https://www.ncbi.nlm.nih.gov/gene/525931", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR000072", "url": "https://www.ebi.ac.uk/interpro/entry/IPR000072", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR000859", "url": "https://www.ebi.ac.uk/interpro/entry/IPR000859", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR029034", "url": "https://www.ebi.ac.uk/interpro/entry/IPR029034", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR035914", "url": "https://www.ebi.ac.uk/interpro/entry/IPR035914", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "A0A3Q1LRU5", "url": "https://www.orthodb.org/?gene=A0A3Q1LRU5", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR11633", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR11633", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR11633:SF4", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR11633:SF4", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00341", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00341", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF00431", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00431", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "XP_005215787", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_005215787", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A3Q1LRU5", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1LRU5", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A3Q1LRU5-1", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1LRU5-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0AAA9SQ24", "url": "https://www.uniprot.org/uniprotkb/A0AAA9SQ24", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0AAA9SQ24-1", "url": "https://www.uniprot.org/uniprotkb/A0AAA9SQ24-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0AAA9TMX2", 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OS=Bos taurus OX=9913 GN=PDGFD PE=3 SV=1 CANONICAL=F6RXK0-1" }, "isoforms": [ { "isoform_ac": "A0A3Q1LRU5-1", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1LRU5/entry", "sequence": { "sequence": "CSPPLPCFVFPFQQYIVRCLTDEESNHLTDLYRRDETIEVTGHGHVQSPRFPNSYPRNLLLTWRLHSQEKTRIQLAFDNQFGLEEAENDICRYDFVEVEDISETSTVIRGRWCGHKEVPPRIISRTNQIKITFKSDDYFVAKPGFKIYYSFVEYFQPAAASETNWESVTSSISGISYHSPSVTDPTLTADALDKTIAEFDTVEDLLKHFNPESWQEDLENLYLDTPHHRGRSYHDRKSKVDLDRLNDDVKRYSCTPRNYSVNLREELKLTNVVFFPRCLLVQRCGGNCGCGTVNWKSCACNSGKTVKKYHEVLKFEPGYFKRRGRAKHMALVDIQLDHHERCDCICSSRPPR", "length": 352, "header": "tr|A0A3Q1LRU5-1|A0A3Q1LRU5_BOVIN Computationally mapped isoform of Platelet-derived growth factor D OS=Bos taurus OX=9913 GN=PDGFD PE=3 SV=2 CANONICAL=F6RXK0-1" }, "locus": { "chromosome": "15", "start_pos": 4535268, "end_pos": 4432254, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000084107.2", "url": "https://www.ensembl.org/id/ENSBTAT00000084107.2" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000059907.2", "url": "https://www.ensembl.org/id/ENSBTAP00000059907.2" } ] } }, { "isoform_ac": "A0AAA9SQ24-1", "url": "https://www.uniprot.org/uniprotkb/A0AAA9SQ24/entry", "sequence": { "sequence": "MHRLVLVYTLVCANFCSYRDTSATPQSASIKALRNANLRRDESNHLTDLYRRDETIEVTGHGHVQSPRFPNSYPRNLLLTWRLHSQEKTRIQLAFDNQFGLEEAENDICRYDFVEVEDISETSTVIRGRWCGHKEVPPRIISRTNQIKITFKSDDYFVAKPGFKIYYSFVGISYHSPSVTDPTLTADALDKTIAEFDTVEDLLKHFNPESWQEDLENLYLDTPHHRGRSYHDRKSKVDLDRLNDDVKRYSCTPRNYSVNLREELKLTNVVFFPRCLLVQRCGGNCGCGTVNWKSCACNSGKTVKKYHEVLKFEPGYFKRRGRAKHMALVDIQLDHHERCDCICSSRPPR", "length": 349, "header": "tr|A0AAA9SQ24-1|F6RXK0_BOVIN Computationally mapped isoform of Platelet-derived growth factor D OS=Bos taurus OX=9913 GN=PDGFD PE=3 SV=1 CANONICAL=F6RXK0-1" }, "locus": { "chromosome": "15", "start_pos": 4535268, "end_pos": 4259626, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000111510.2", "url": "https://www.ensembl.org/id/ENSBTAT00000111510.2" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000088420.1", "url": "https://www.ensembl.org/id/ENSBTAP00000088420.1" } ] } }, { "isoform_ac": "A0AAA9TMX2-1", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TMX2/entry", "sequence": { "sequence": "CISDKFPADDADLGDHTLRTTVVQDESQKSNHLTDLYRRDETIEVTGHGHVQSPRFPNSYPRNLLLTWRLHSQEKTRIQLAFDNQFGLEEAENDICRYDFVEVEDISETSTVIRGRWCGHKEVPPRIISRTNQIKITFKSDDYFVAKPGFKIYYSFVEYFQPAAASETNWESVTSSISGISYHSPSVTDPTLTADALDKTIAEFDTVEDLLKHFNPESWQEDLENLYLDTPHHRGRSYHDRKSKVDLDRLNDDVKRYSCTPRNYSVNLREELKLTNVVFFPRCLLVQRCGGNCGCGTVNWKSCACNSGKTVKKYHEVLKFEPGYFKRRGRAKHMALVDIQLDHHERCDCICSSRPPR", "length": 357, "header": "tr|A0AAA9TMX2-1|F6RXK0_BOVIN Computationally mapped isoform of Platelet-derived growth factor D OS=Bos taurus OX=9913 GN=PDGFD PE=3 SV=1 CANONICAL=F6RXK0-1" }, "locus": { "chromosome": "15", "start_pos": 4535268, "end_pos": 4435034, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000116998.1", "url": "https://www.ensembl.org/id/ENSBTAT00000116998.1" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000098338.1", "url": "https://www.ensembl.org/id/ENSBTAP00000098338.1" } ] } }, { "isoform_ac": "F6RXK0-1", "url": "https://www.uniprot.org/uniprotkb/F6RXK0/entry", "sequence": { "sequence": "MHRLVLVYTLVCANFCSYRDTSATPQSASIKALRNANLRRDESNHLTDLYRRDETIEVTGHGHVQSPRFPNSYPRNLLLTWRLHSQEKTRIQLAFDNQFGLEEAENDICRYDFVEVEDISETSTVIRGRWCGHKEVPPRIISRTNQIKITFKSDDYFVAKPGFKIYYSFVEYFQPAAASETNWESVTSSISGISYHSPSVTDPTLTADALDKTIAEFDTVEDLLKHFNPESWQEDLENLYLDTPHHRGRSYHDRKSKVDLDRLNDDVKRYSCTPRNYSVNLREELKLTNVVFFPRCLLVQRCGGNCGCGTVNWKSCACNSGKTVKKYHEVLKFEPGYFKRRGRAKHMALVDIQLDHHERCDCICSSRPPR", "length": 370, "header": "tr|F6RXK0-1|F6RXK0_BOVIN Isoform 1 of Platelet-derived growth factor D OS=Bos taurus OX=9913 GN=PDGFD PE=3 SV=1 CANONICAL=F6RXK0-1" }, "locus": { "chromosome": "15", "start_pos": 4535268, "end_pos": 4259626, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000049292.5", "url": "https://www.ensembl.org/id/ENSBTAT00000049292.5" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000046207.3", "url": "https://www.ensembl.org/id/ENSBTAP00000046207.3" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [], "orthologs": [], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 2, "go_terms": [ { "name": "extracellular region", "id": "GO:0005576", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005576", "evidence": [ { "database": "UniProtKB", "id": "F6RXK0", "url": "https://www.uniprot.org/uniprotkb/F6RXK0" } ], "pmid": "" }, { "name": "membrane", "id": "GO:0016020", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016020", "evidence": [ { "database": "UniProtKB", "id": "F6RXK0", "url": "https://www.uniprot.org/uniprotkb/F6RXK0" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 1, "go_terms": [ { "name": "positive regulation of cell division", "id": "GO:0051781", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0051781", "evidence": [ { "database": "UniProtKB", "id": "F6RXK0", "url": "https://www.uniprot.org/uniprotkb/F6RXK0" } ], "pmid": "" } ] }, { "name": "Molecular Function", "total": 1, "go_terms": [ { "name": "growth factor activity", "id": "GO:0008083", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008083", "evidence": [ { "database": "UniProtKB", "id": "F6RXK0", "url": "https://www.uniprot.org/uniprotkb/F6RXK0" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 276, "end_pos": 278, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "F6RXK0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F6RXK0" }, { "id": "PS01180", "database": "PROSITE", "url": "https://prosite.expasy.org/PS01180" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "CUB", "eco_id": "ECO_0000259", "start_pos": 52, "end_pos": 170, "start_aa": "Arg", "end_aa": "Val", "glycosite_overlap": [] }, { "evidence": [ { "id": "F6RXK0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F6RXK0" }, { "id": "PS50278", "database": "PROSITE", "url": "https://prosite.expasy.org/PS50278" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "Platelet-derived growth factor (PDGF) family profile", "eco_id": "ECO_0000259", "start_pos": 259, "end_pos": 362, "start_aa": "Asp", "end_aa": "Cys", "glycosite_overlap": [] } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 276, "end_pos": 278 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ], "tool_support": { "graph_view": "yes" } }, { "uniprot_canonical_ac": "G3X7S5-1", "uniprot_ac": "G3X7S5", "uniprot_id": "G3X7S5_BOVIN", "mass": { "chemical_mass": 86583.0, "monoisotopic_mass": 86583.0 }, "refseq": {}, "gene_names": [ { "name": "ZXDB", "type": "recommended", "evidence": [ { "id": "G3X7S5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3X7S5" } ] } ], "protein_names": [ { "name": "C2H2-type domain-containing protein", "type": "recommended", "evidence": [ { "id": "G3X7S5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3X7S5/entry#names_and_taxonomy" } ] } ], "function": [ { "annotation": "Cooperates with CIITA to promote transcription of MHC class I and MHC class II genes.", "evidence": [ { "database": "UniProtKB", "id": "A0AAA9SQN2", "url": "https://www.uniprot.org/uniprotkb/A0AAA9SQN2#function" }, { "database": "UniProtKB", "id": "ARBA00053079", "url": "https://www.uniprot.org/uniprotkb/ARBA00053079#function" }, { "database": "UniProtKB", "id": "A0AAA9SZ49", "url": "https://www.uniprot.org/uniprotkb/A0AAA9SZ49#function" }, { "database": "UniProtKB", "id": "A0AAA9TGK8", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TGK8#function" }, { "database": "UniProtKB", "id": "G3X6Q6", "url": "https://www.uniprot.org/uniprotkb/G3X6Q6#function" }, { "database": "UniProtKB", "id": "G3X7S5", "url": "https://www.uniprot.org/uniprotkb/G3X7S5#function" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Bos taurus", "taxid": 9913, "evidence": [ { "database": "UniProtKB", "id": "G3X7S5", "url": "https://www.uniprot.org/uniprotkb/G3X7S5" } ], "common_name": "Bovine", "glygen_name": "Bovine", "reference_species": "Bos taurus [9913]" } ], "gene": [ { "name": "ZXDB", "url": "https://www.uniprot.org/uniprotkb/G3X7S5", "locus": {} } ], "crossref": [ { "id": "G3X7S5", "url": "https://alphafold.ebi.ac.uk/entry/G3X7S5", "database": "AlphaFoldDB", "categories": [] }, { "id": "ENSBTAG00000008911", "url": "https://bgee.org/?page=gene&gene_id=ENSBTAG00000008911", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "ENSBTAG00000031523", "url": "https://bgee.org/?page=gene&gene_id=ENSBTAG00000031523", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "783265", "url": "https://www.ncbi.nlm.nih.gov/gene/783265", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR013087", "url": "https://www.ebi.ac.uk/interpro/entry/IPR013087", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR036236", "url": "https://www.ebi.ac.uk/interpro/entry/IPR036236", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR051061", "url": "https://www.ebi.ac.uk/interpro/entry/IPR051061", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "bta:783265", "url": "https://www.genome.jp/dbget-bin/www_bget?bta:783265", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "CEVCEDS", "url": "https://omabrowser.org/oma/group/CEVCEDS/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "G3X7S5", "url": "https://www.orthodb.org/?gene=G3X7S5", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR46179", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR46179", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR46179:SF6", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR46179:SF6", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00096", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00096", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "A0AAA9SQN2", "url": "https://www.uniprot.org/uniprotkb/A0AAA9SQN2", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0AAA9SQN2-1", "url": "https://www.uniprot.org/uniprotkb/A0AAA9SQN2-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0AAA9SZ49", "url": "https://www.uniprot.org/uniprotkb/A0AAA9SZ49", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0AAA9SZ49-1", "url": "https://www.uniprot.org/uniprotkb/A0AAA9SZ49-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0AAA9TGK8", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TGK8", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0AAA9TGK8-1", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TGK8-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "G3X6Q6", "url": "https://www.uniprot.org/uniprotkb/G3X6Q6", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "G3X6Q6-1", "url": "https://www.uniprot.org/uniprotkb/G3X6Q6-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "G3X7S5", "url": "https://www.uniprot.org/uniprotkb/G3X7S5", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "G3X7S5-1", "url": "https://www.uniprot.org/uniprotkb/G3X7S5-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MEIPRLLPARGMRQTGGAGSPEGGGRIRGGANLRAGQAPARRLLLLRGPQDGGPGRRREEASAASSCPGPAPSPLALRPDHATGCGSGGGSGGDDFFLVLLDPVGGDVETAGAGQAAGPVWREEAGLGPRLLGGESGANPEGRPALGPSCLSAIPAPVPALAPIPAPGLGPATAFAGTVTIHNQNLLLSLENGILTLATPPPPAWAPGVAPAPQPRGLVAPQAGIPHAAESGDCPELPPDLLLAERAEPAPAPAPKEEEEGPAAVESPRGPPGPGQGVLLYLCPEVQCGQTFAKKHQLKVHLLTHSSSQGQRPFKCPLGGCGWTFTTSYKLKRHLQSHDKLRPFGCPAEGCGKSFTTVYNLKAHMKGHEQENSFKCEVCEDTFPTQAKLSAHQRSHFEPERPYQCAFSGCKKTFITVSALFSHNRAHFREQELFSCSFPGCSKQYDKACRLKIHLRSHTGERPFLCDFEGCGWNFTSMSKLLRHKRKHDDDRRFMCPVEGCGKSFTRAEHLKGHSITHLGTKPFVCPVEGCCARFSARSSLYIHSKKHLQDVDTWKSRCPVATCNKLFTSKHSMKTHMAKRHNLRQDLLAQLEAANSLTPSSELTSQGQSDLSDAELVSLFSDVPGNNSSAAVLDTALVNSGILTIDVASVNSTLAGNLPANNNNSLGQAVDPQALMATSDLPQSLDTSLFFGTTAAGFQQGPLDMDDVSSLSAGPLASLSSLALKNSSQEPQALIPSSKLTVDTDALTPSSTLCENSVSELLPPTKTEWNVHPDSDFFAQEEETQFGFSNPAGNHGSQKETDLITVTGSSFLLITW", "length": 817, "header": "tr|G3X7S5-1|G3X7S5_BOVIN Isoform 1 of C2H2-type domain-containing protein OS=Bos taurus OX=9913 GN=ZXDB PE=3 SV=2 CANONICAL=G3X7S5-1" }, "isoforms": [ { "isoform_ac": "A0AAA9SQN2-1", "url": "https://www.uniprot.org/uniprotkb/A0AAA9SQN2/entry", "sequence": { "sequence": "MEIPRLLPARGMRQTGGAGSPEGGGRIRGGANLRAGQAPARRLLLLRGPQDGGPGRRREEASAASSCPGPAPSPLALRPDHATGCGSGGGSGGDDFFLVLLDPVGGDVETAGAGQAAGPVWREEAGLGPRLLGGESGANPEGRPALGPSCLSAIPAPVPALAPIPAPGLGPATAFAGTVTIHNQNLLLSLENGILTLATPPPPAWAPGVAPAPQPRGLVAPQAGIPHAAESGDCPELPPDLLLAERAEPAPAPAPKEEEEGPAAVESPRGPPGPGQGVLLYLCPEVQCGQTFAKKHQLKVHLLTHSSSQGQRPFKCPLGGCGWTFTTSYKLKRHLQSHDKLRPFGCPAEGCGKSFTTVYNLKAHMKGHEQENSFKCEVCEDTFPTQAKLSAHQRSHFEPERPYQCAFSGCKKTFITVSALFSHNRAHFREQELFSCSFPGCSKQYDKACRLKIHLRSHTGERPFLCDFEGCGWNFTSMSKLLRHKRKHDDDRRFMCPVEGCGKSFTRAEHLKGHSITHLGTKPFVCPVEGCCARFSARSSLYIHSKKHLQDVDTWKSRCPVATCNKLFTSKHSMKTHMAKRHNLRQDLLAQLEAANSLTPSSELTSQGQSDLSDAELVSLFSDVPGNNSSAAVLDTALVNSGILTIDVASVNSTLAGNLPANNNNSLGQAVDPQALMATSDLPQSLDTSLFFGTTAAGFQQGPLDMDDVSSLSAGPLASLSSLALKNSSQEPQALIPSSKLTVDTDALTPSSTLCENSVSELLPPTKTEWNVHPDSDFFAQEEETQFGFSNPAGNHGSQKETDLITVTGSSFL", "length": 813, "header": "tr|A0AAA9SQN2-1|G3X7S5_BOVIN Computationally mapped isoform of C2H2-type domain-containing protein OS=Bos taurus OX=9913 GN=ZXDB PE=3 SV=1 CANONICAL=G3X7S5-1" }, "locus": { "chromosome": "X", "start_pos": 97202796, "end_pos": 97200358, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000099801.1", "url": "https://www.ensembl.org/id/ENSBTAT00000099801.1" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000086255.1", "url": "https://www.ensembl.org/id/ENSBTAP00000086255.1" } ] } }, { "isoform_ac": "A0AAA9SZ49-1", "url": "https://www.uniprot.org/uniprotkb/A0AAA9SZ49/entry", "sequence": { "sequence": "MEIPRLLPARGMRQTGGAGSPEGGGRIRGGANLRAGQAPARRLLLLRGPQDGGPGRRREEASAASSCPGPAPSPLALRPDHATGCGSGGGSGGDDFFLVLLDPVGGDVETAGAGQAAGPVWREEAGLGPRLLGGESGANPEGRPALGPSCLSAIPAPVPALAPIPAPGLGPATAFAGTVTIHNQNLLLSLENGILTLATPPPPAWAPGVAPAPQPRGLVAPQAGIPHAAESGDCPELPPDLLLAERAEPAPAPAPKEEEEGPAAVESPRGPPGPGQGVLLYLCPEVQCGQTFAKKHQLKVHLLTHSSSQGQRPFKCPLGGCGWTFTTSYKLKRHLQSHDKLRPFGCPAEGCGKSFTTVYNLKAHMKGHEQENSFKCEVCEDTFPTQAKLSAHQRSHFEPERPYQCAFSGCKKTFITVSALFSHNRAHFREQELFSCSFPGCSKQYDKACRLKIHLRSHTGERPFLCDFEGCGWNFTSMSKLLRHKRKHDDDRRFMCPVEGCGKSFTRAEHLKGHSITHLGTKPFVCPVEGCCARFSARSSLYIHSKKHLQDVDTWKSRCPVATCNKLFTSKHSMKTHMAKRHNLRQDLLAQLEAANSLTPSSELTSQGQSDLSDAELVSLFSDVPGNNSSAAVLDTALVNSGILTIDVASVNSTLAGNLPANNNNSLGQAVDPQALMATSDLPQSLDTSLFFGTTAAGFQQGPLDMDDVSSLSAGPLASLSSLALKNSSQEPQALIPSSKLTVDTDALTPSSTLCENSVSELLPPTKTEWNVHPDSDFFAQEEETQFGFSNPAGNHGSQKETDLITVTGSSFLMIPP", "length": 817, "header": "tr|A0AAA9SZ49-1|G3X7S5_BOVIN Computationally mapped isoform of C2H2-type domain-containing protein OS=Bos taurus OX=9913 GN=ZXDB PE=3 SV=1 CANONICAL=G3X7S5-1" }, "locus": { "chromosome": "X", "start_pos": 97202796, "end_pos": 97087038, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000124004.2", "url": "https://www.ensembl.org/id/ENSBTAT00000124004.2" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000090671.1", "url": "https://www.ensembl.org/id/ENSBTAP00000090671.1" } ] } }, { "isoform_ac": "A0AAA9TGK8-1", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TGK8/entry", "sequence": { "sequence": "MEIPRLLPARGMRQTGGAGSPEGGGRIRGGANLRAGQAPARRLLLLRGPQDGGPGRRREEASAASSCPGPAPSPLALRPDHATGCGSGGGSGGDDFFLVLLDPVGGDVETAGAGQAAGPVWREEAGLGPRLLGGESGANPEGRPALGPSCLSAIPAPVPALAPIPAPGLGPATAFAGTVTIHNQNLLLSLENGILTLATPPPPAWAPGVAPAPQPRGLVAPQAGIPHAAESGDCPELPPDLLLAERAEPAPAPAPKEEEEGPAAVESPRGPPGPGQGVLLYLCPEVQCGQTFAKKHQLKVHLLTHSSSQGQRPFKCPLGGCGWTFTTSYKLKRHLQSHDKLRPFGCPAEGCGKSFTTVYNLKAHMKGHEQENSFKCEVCEDTFPTQAKLSAHQRSHFEPERPYQCAFSGCKKTFITVSALFSHNRAHFREQELFSCSFPGCSKQYDKACRLKIHLRSHTGERPFLCDFEGCGWNFTSMSKLLRHKRKHDDDRRFMCPVEGCGKSFTRAEHLKGHSITHLGTKPFVCPVEGCCARFSARSSLYIHSKKHLQDVDTWKSRCPVATCNKLFTSKHSMKTHMAKRHNLRQDLLAQLEAANSLTPSSELTSQGQSDLSDAELVSLFSDVPGNNSSAAVLDTALVNSGILTIDVASVNSTLAGNLPANNNNSLGQAVDPQALMATSDLPQSLDTSLFFGTTAAGFQQGPLDMDDVSSLSAGPLASLSSLALKNSSQEPQALIPSSKLTVDTDALTPSSTLCENSVSELLPPTKTEWNVHPDSDFFAQEEETQFGFSNPAGNHGSQKETDLITVTGSSFLV", "length": 814, "header": "tr|A0AAA9TGK8-1|G3X7S5_BOVIN Computationally mapped isoform of C2H2-type domain-containing protein OS=Bos taurus OX=9913 GN=ZXDB PE=3 SV=1 CANONICAL=G3X7S5-1" }, "locus": { "chromosome": "X", "start_pos": 97202796, "end_pos": 97200247, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000134930.1", "url": "https://www.ensembl.org/id/ENSBTAT00000134930.1" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000097686.1", "url": "https://www.ensembl.org/id/ENSBTAP00000097686.1" } ] } }, { "isoform_ac": "G3X6Q6-1", "url": "https://www.uniprot.org/uniprotkb/G3X6Q6/entry", "sequence": { "sequence": "MEIPRLLPARGMRQTGGAGSPEGGGRIRGGANLRAGQAPARRLLLLRGPQDGGPGRRREEASAASSCPGPAPSPLALRPDHATGCGSGGGSGGDDFFLVLLDPVGGDVETAGAGQAAGPVWREEAGLGPRLLGGESGANPEGRPALGPSCLSAIPAPVPALAPIPAPGLGPATAFAGTVTIHNQNLLLSLENGILTLATPPPPAWAPGVAPAPQPRGLVAPQAGIPHAAESGDCPELPPDLLLAERAEPAPAPAPKEEEEGPAAVESPRGPPGPGQGVLLYLCPEVQCGQTFAKKHQLKVHLLTHSSSQGQRPFKCPLGGCGWTFTTSYKLKRHLQSHDKLRPFGCPAEGCGKSFTTVYNLKAHMKGHEQENSFKCEVCEDTFPTQAKLSAHQRSHFEPERPYQCAFSGCKKTFITVSALFSHNRAHFREQELFSCSFPGCSKQYDKACRLKIHLRSHTGERPFLCDFEGCGWNFTSMSKLLRHKRKHDDDRRFMCPVEGCGKSFTRAEHLKGHSITHLGTKPFVCPVEGCCARFSARSSLYIHSKKHLQDVDTWKSRCPVATCNKLFTSKHSMKTHMAKRHNLRQDLLAQLEAANSLTPSSELTSQGQSDLSDAELVSLFSDVPGNNSSAAVLDTALVNSGILTIDVASVNSTLAGNLPANNNNSLGQAVDPQALMATSDLPQSLDTSLFFGTTAAGFQQGPLDMDDVSSLSAGPLASLSSLALKNSSQEPQALIPSSKLTVDTDALTPSSTLCENSVSELLPPTKTEWNVHPDSDFFAQEEETQFGFSNPAGNHGSQKETDLITVTGSSFLSTAALALGLLHNP", "length": 826, "header": "tr|G3X6Q6-1|G3X6Q6_BOVIN Computationally mapped isoform of C2H2-type domain-containing protein OS=Bos taurus OX=9913 GN=ZXDB PE=3 SV=3 CANONICAL=G3X7S5-1" }, "locus": { "chromosome": "X", "start_pos": 97202796, "end_pos": 97180401, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000011730.7", "url": "https://www.ensembl.org/id/ENSBTAT00000011730.7" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000011730.7", "url": "https://www.ensembl.org/id/ENSBTAP00000011730.7" } ] } }, { "isoform_ac": "G3X7S5-1", "url": "https://www.uniprot.org/uniprotkb/G3X7S5/entry", "sequence": { "sequence": "MEIPRLLPARGMRQTGGAGSPEGGGRIRGGANLRAGQAPARRLLLLRGPQDGGPGRRREEASAASSCPGPAPSPLALRPDHATGCGSGGGSGGDDFFLVLLDPVGGDVETAGAGQAAGPVWREEAGLGPRLLGGESGANPEGRPALGPSCLSAIPAPVPALAPIPAPGLGPATAFAGTVTIHNQNLLLSLENGILTLATPPPPAWAPGVAPAPQPRGLVAPQAGIPHAAESGDCPELPPDLLLAERAEPAPAPAPKEEEEGPAAVESPRGPPGPGQGVLLYLCPEVQCGQTFAKKHQLKVHLLTHSSSQGQRPFKCPLGGCGWTFTTSYKLKRHLQSHDKLRPFGCPAEGCGKSFTTVYNLKAHMKGHEQENSFKCEVCEDTFPTQAKLSAHQRSHFEPERPYQCAFSGCKKTFITVSALFSHNRAHFREQELFSCSFPGCSKQYDKACRLKIHLRSHTGERPFLCDFEGCGWNFTSMSKLLRHKRKHDDDRRFMCPVEGCGKSFTRAEHLKGHSITHLGTKPFVCPVEGCCARFSARSSLYIHSKKHLQDVDTWKSRCPVATCNKLFTSKHSMKTHMAKRHNLRQDLLAQLEAANSLTPSSELTSQGQSDLSDAELVSLFSDVPGNNSSAAVLDTALVNSGILTIDVASVNSTLAGNLPANNNNSLGQAVDPQALMATSDLPQSLDTSLFFGTTAAGFQQGPLDMDDVSSLSAGPLASLSSLALKNSSQEPQALIPSSKLTVDTDALTPSSTLCENSVSELLPPTKTEWNVHPDSDFFAQEEETQFGFSNPAGNHGSQKETDLITVTGSSFLLITW", "length": 817, "header": "tr|G3X7S5-1|G3X7S5_BOVIN Isoform 1 of C2H2-type domain-containing protein OS=Bos taurus OX=9913 GN=ZXDB PE=3 SV=2 CANONICAL=G3X7S5-1" }, "locus": { "chromosome": "X", "start_pos": 97202796, "end_pos": 97124046, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000044683.5", "url": "https://www.ensembl.org/id/ENSBTAT00000044683.5" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000042160.4", "url": "https://www.ensembl.org/id/ENSBTAP00000042160.4" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [ { "id": "bta:783265", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?bta:783265", "resource": "KEGG Pathway" } ], "orthologs": [ { "uniprot_canonical_ac": "P98168-1", "protein_name": "Zinc finger X-linked protein ZXDA", "gene_name": "ZXDA", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MEIPKLLPARGTLQGGGGGGIPAGGGRVHRGPDSPAGQVPTRRLLLPRGPQDGGPGRRREEASTASRGPGPSLFAPRPHQPSGGGDDFFLVLLDPVGGDVETAGSGQAAGPVLREEAKAGPGLQGDESGANPAGCSAQGPHCLSAVPTPAPISAPGPAAAFAGTVTIHNQDLLLRFENGVLTLATPPPHAWEPGAAPAQQPRCLIAPQAGFPQAAHPGDCPELRSDLLLAEPAEPAPAPAPQEEAEGLAAALGPRGLLGSGPGVVLYLCPEALCGQTFAKKHQLKMHLLTHSSSQGQRPFKCPLGGCGWTFTTSYKLKRHLQSHDKLRPFGCPAEGCGKSFTTVYNLKAHMKGHEQENSFKCEVCEESFPTQAKLGAHQRSHFEPERPYQCAFSGCKKTFITVSALFSHNRAHFREQELFSCSFPGCSKQYDKACRLKIHLRSHTGERPFLCDFDGCGWNFTSMSKLLRHKRKHDDDRRFMCPVEGCGKSFTRAEHLKGHSITHLGTKPFVCPVAGCCARFSARSSLYIHSKKHLQDVDTWKSRCPISSCNKLFTSKHSMKTHMVKRHKVGQDLLAQLEAANSLTPSSELTSQRQNDLSDAEIVSLFSDVPDSTSAALLDTALVNSGILTIDVASVSSTLAGHLPANNNNSVGQAVDPPSLMATSDPPQSLDTSLFFGTAATGFQQSSLNMDEVSSVSVGPLGSLDSLAMKNSSPEPQALTPSSKLTVDTDTLTPSSTLCENSVSELLTPAKAEWSVHPNSDFFGQEGETQFGFPNAAGNHGSQKERNLITVTGSSFLV", "length": 799 }, "evidence": [ { "id": "G3X7S5", "url": "https://omabrowser.org/oma/group/G3X7S5/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" } ], "go_annotation": { "categories": [ { "name": "Molecular Function", "total": 4, "go_terms": [ { "name": "transcription coactivator activity", "id": "GO:0003713", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003713", "evidence": [ { "database": "UniProtKB", "id": "G3X7S5", "url": "https://www.uniprot.org/uniprotkb/G3X7S5" } ], "pmid": "" }, { "name": "zinc ion binding", "id": "GO:0008270", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008270", "evidence": [ { "database": "UniProtKB", "id": "G3X7S5", "url": "https://www.uniprot.org/uniprotkb/G3X7S5" } ], "pmid": "" }, { "name": "C2H2 zinc finger domain binding", "id": "GO:0070742", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0070742", "evidence": [ { "database": "UniProtKB", "id": "G3X7S5", "url": "https://www.uniprot.org/uniprotkb/G3X7S5" } ], "pmid": "" }, { "name": "transcription coregulator activity", "id": "GO:0003712", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003712", "evidence": [ { "database": "UniProtKB", "id": "G3X7S5", "url": "https://www.uniprot.org/uniprotkb/G3X7S5" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 1, "go_terms": [ { "name": "nucleus", "id": "GO:0005634", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005634", "evidence": [ { "database": "UniProtKB", "id": "G3X7S5", "url": "https://www.uniprot.org/uniprotkb/G3X7S5" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 2, "go_terms": [ { "name": "DNA-templated transcription", "id": "GO:0006351", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006351", "evidence": [ { "database": "UniProtKB", "id": "G3X7S5", "url": "https://www.uniprot.org/uniprotkb/G3X7S5" } ], "pmid": "" }, { "name": "regulation of transcription by RNA polymerase II", "id": "GO:0006357", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006357", "evidence": [ { "database": "UniProtKB", "id": "G3X7S5", "url": "https://www.uniprot.org/uniprotkb/G3X7S5" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 474, "end_pos": 476, "annotation": "n_glycosylation_sequon" }, { "start_pos": 627, "end_pos": 629, "annotation": "n_glycosylation_sequon" }, { "start_pos": 628, "end_pos": 630, "annotation": "n_glycosylation_sequon" }, { "start_pos": 652, "end_pos": 654, "annotation": "n_glycosylation_sequon" }, { "start_pos": 664, "end_pos": 666, "annotation": "n_glycosylation_sequon" }, { "start_pos": 727, "end_pos": 729, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [ { "pdb_id": "AF-G3X7S5-F1", "pdb_chain": "global", "start_pos": 1, "end_pos": 817, "overlap": "1.0", "method": "AlphaFold", "type": "alphafold", "resolution": -1.0, "url": "https://data.glygen.org/ln2downloads/pdb/current/AF-G3X7S5-F1.pdb", "url_external": "https://alphafold.ebi.ac.uk/entry/G3X7S5" } ], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "G3X7S5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3X7S5" }, { "id": "PS50157", "database": "PROSITE", "url": "https://prosite.expasy.org/PS50157" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "C2H2-type", "eco_id": "ECO_0000259", "start_pos": 281, "end_pos": 310, "start_aa": "Tyr", "end_aa": "Gly", "glycosite_overlap": [] } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" }, { "name": "homologset.oma", "label": "OMA Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 474, "end_pos": 476 }, { "start_pos": 627, "end_pos": 629 }, { "start_pos": 628, "end_pos": 630 }, { "start_pos": 652, "end_pos": 654 }, { "start_pos": 664, "end_pos": 666 }, { "start_pos": 727, "end_pos": 729 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ], "tool_support": { "graph_view": "yes" } }, { "uniprot_canonical_ac": "F6RQM8-1", "uniprot_ac": "F6RQM8", "uniprot_id": "F6RQM8_BOVIN", "mass": { "chemical_mass": 20208.0, "monoisotopic_mass": 20208.0 }, "refseq": { "ac": "XP_015314310", "name": "receptor activity-modifying protein 2 isoform X1", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_015314310" }, "gene_names": [ { "name": "RAMP2", "type": "recommended", "evidence": [ { "id": "F6RQM8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F6RQM8" } ] }, { "name": "RAMP2", "type": "synonym", "evidence": [ { "id": "XP_015314310", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_015314310" } ] } ], "protein_names": [ { "name": "Receptor activity-modifying protein 2", "type": "recommended", "evidence": [ { "id": "F6RQM8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F6RQM8/entry#names_and_taxonomy" } ] }, { "name": "receptor activity-modifying protein 2 isoform X1", "type": "synonym", "evidence": [ { "id": "XP_015314310", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_015314310" } ] } ], "function": [ { "annotation": "Accessory protein that interacts with and modulates the function of G-protein coupled receptors including calcitonin gene-related peptide type 1 receptor (CALCRL) and calcitonin receptor (CALCR). Required for the transport of CALCRL to the plasma membrane. Together with CALCRL, form a receptor complex for adrenomedullin/ADM. Together with CALCR, act as a receptor complex for calcitonin/CT/CALC. Together with CALCR, also act as a receptor complex for amylin/IAPP.", "evidence": [ { "database": "UniProtKB", "id": "F6RQM8", "url": "https://www.uniprot.org/uniprotkb/F6RQM8#function" }, { "database": "UniProtKB", "id": "ARBA00056007", "url": "https://www.uniprot.org/uniprotkb/ARBA00056007#function" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Bos taurus", "taxid": 9913, "evidence": [ { "database": "UniProtKB", "id": "F6RQM8", "url": "https://www.uniprot.org/uniprotkb/F6RQM8" } ], "common_name": "Bovine", "glygen_name": "Bovine", "reference_species": "Bos taurus [9913]" } ], "gene": [ { "name": "RAMP2", "url": "https://www.uniprot.org/uniprotkb/F6RQM8", "locus": { "chromosome": "19", "start_pos": 42802111, "end_pos": 42800260, "strand": "-", "evidence": [ { "database": "Ensembl Gene", "id": "ENSBTAG00000019903", "url": "https://www.ensembl.org/id/ENSBTAG00000019903" } ] } } ], "crossref": [ { "id": "F6RQM8", "url": "https://alphafold.ebi.ac.uk/entry/F6RQM8", "database": "AlphaFoldDB", "categories": [] }, { "id": "504230", "url": "https://www.ncbi.nlm.nih.gov/gene/504230", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR006985", "url": "https://www.ebi.ac.uk/interpro/entry/IPR006985", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR038126", "url": "https://www.ebi.ac.uk/interpro/entry/IPR038126", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "PTHR14076", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR14076", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR14076:SF9", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR14076:SF9", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF04901", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF04901", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "XP_015314310", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_015314310", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0AAA9SSC9", "url": "https://www.uniprot.org/uniprotkb/A0AAA9SSC9", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0AAA9SSC9-1", "url": "https://www.uniprot.org/uniprotkb/A0AAA9SSC9-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "F6RQM8", "url": "https://www.uniprot.org/uniprotkb/F6RQM8", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "F6RQM8-1", "url": "https://www.uniprot.org/uniprotkb/F6RQM8-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MASLRAEHAVGGSWLPATRSGRPAALRLLLLLGAVLKPQESLAQLLPTPDSSKSEASLPTGKTVLETYGTNVLQCWHDYKVQMDSIKKDWCDWALISRPYSFLRDCLEKGAEEFGLGFPNPWAEEIIFETHNIHFANCSLVQPTFSDPPEDVLLAMIIAPICLIPFLVTLVVWRSKDSEAQT", "length": 182, "header": "tr|F6RQM8-1|F6RQM8_BOVIN Isoform 1 of Receptor activity-modifying protein 2 OS=Bos taurus OX=9913 GN=RAMP2 PE=3 SV=1 CANONICAL=F6RQM8-1" }, "isoforms": [ { "isoform_ac": "A0AAA9SSC9-1", "url": "https://www.uniprot.org/uniprotkb/A0AAA9SSC9/entry", "sequence": { "sequence": "MASLRAEHAVGGSWLPATRSGRPAALRLLLLLGAVLKPQESLAQLLPTPDSSKSEGLIASFETAWKRVQKSLAWASPIPGRKRSSLRLTTSTLPTAPWCNPPSQTPQRMCSWP", "length": 113, "header": "tr|A0AAA9SSC9-1|F6RQM8_BOVIN Computationally mapped isoform of Receptor activity-modifying protein 2 OS=Bos taurus OX=9913 GN=RAMP2 PE=3 SV=1 CANONICAL=F6RQM8-1" }, "locus": { "chromosome": "19", "start_pos": 42801835, "end_pos": 42800376, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000096019.2", "url": "https://www.ensembl.org/id/ENSBTAT00000096019.2" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000085924.1", "url": "https://www.ensembl.org/id/ENSBTAP00000085924.1" } ] } }, { "isoform_ac": "F6RQM8-1", "url": "https://www.uniprot.org/uniprotkb/F6RQM8/entry", "sequence": { "sequence": "MASLRAEHAVGGSWLPATRSGRPAALRLLLLLGAVLKPQESLAQLLPTPDSSKSEASLPTGKTVLETYGTNVLQCWHDYKVQMDSIKKDWCDWALISRPYSFLRDCLEKGAEEFGLGFPNPWAEEIIFETHNIHFANCSLVQPTFSDPPEDVLLAMIIAPICLIPFLVTLVVWRSKDSEAQT", "length": 182, "header": "tr|F6RQM8-1|F6RQM8_BOVIN Isoform 1 of Receptor activity-modifying protein 2 OS=Bos taurus OX=9913 GN=RAMP2 PE=3 SV=1 CANONICAL=F6RQM8-1" }, "locus": { "chromosome": "19", "start_pos": 42801915, "end_pos": 42800376, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000034789.6", "url": "https://www.ensembl.org/id/ENSBTAT00000034789.6" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000034674.4", "url": "https://www.ensembl.org/id/ENSBTAP00000034674.4" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [], "orthologs": [], "go_annotation": { "categories": [ { "name": "Biological Process", "total": 22, "go_terms": [ { "name": "vasculogenesis", "id": "GO:0001570", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0001570", "evidence": [ { "database": "UniProtKB", "id": "F6RQM8", "url": "https://www.uniprot.org/uniprotkb/F6RQM8" } ], "pmid": "" }, { "name": "intracellular protein transport", "id": "GO:0006886", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006886", "evidence": [ { "database": "UniProtKB", "id": "F6RQM8", "url": "https://www.uniprot.org/uniprotkb/F6RQM8" } ], "pmid": "" }, { "name": "adenylate cyclase-activating G protein-coupled receptor signaling pathway", "id": "GO:0007189", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007189", "evidence": [ { "database": "UniProtKB", "id": "F6RQM8", "url": "https://www.uniprot.org/uniprotkb/F6RQM8" } ], "pmid": "" }, { "name": "heart development", "id": "GO:0007507", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007507", "evidence": [ { "database": "UniProtKB", "id": "F6RQM8", "url": "https://www.uniprot.org/uniprotkb/F6RQM8" } ], "pmid": "" }, { "name": "positive regulation of gene expression", "id": "GO:0010628", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0010628", "evidence": [ { "database": "UniProtKB", "id": "F6RQM8", "url": "https://www.uniprot.org/uniprotkb/F6RQM8" } ], "pmid": "" }, { "name": "receptor internalization", "id": "GO:0031623", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0031623", "evidence": [ { "database": "UniProtKB", "id": "F6RQM8", "url": "https://www.uniprot.org/uniprotkb/F6RQM8" } ], "pmid": "" }, { "name": "protein localization to plasma membrane", "id": "GO:0072659", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0072659", "evidence": [ { "database": "UniProtKB", "id": "F6RQM8", "url": "https://www.uniprot.org/uniprotkb/F6RQM8" } ], "pmid": "" }, { "name": "calcium ion transport", "id": "GO:0006816", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006816", "evidence": [ { "database": "UniProtKB", "id": "F6RQM8", "url": "https://www.uniprot.org/uniprotkb/F6RQM8" } ], "pmid": "" }, { "name": "regulation of blood pressure", "id": "GO:0008217", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008217", "evidence": [ { "database": "UniProtKB", "id": "F6RQM8", "url": "https://www.uniprot.org/uniprotkb/F6RQM8" } ], "pmid": "" }, { "name": "negative regulation of vascular permeability", "id": "GO:0043116", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0043116", "evidence": [ { "database": "UniProtKB", "id": "F6RQM8", "url": "https://www.uniprot.org/uniprotkb/F6RQM8" } ], "pmid": "" }, { "name": "positive regulation of angiogenesis", "id": "GO:0045766", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0045766", "evidence": [ { "database": "UniProtKB", "id": "F6RQM8", "url": "https://www.uniprot.org/uniprotkb/F6RQM8" } ], "pmid": "" }, { "name": "negative regulation of endothelial cell apoptotic process", "id": "GO:2000352", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:2000352", "evidence": [ { "database": "UniProtKB", "id": "F6RQM8", "url": "https://www.uniprot.org/uniprotkb/F6RQM8" } ], "pmid": "" }, { "name": "bicellular tight junction assembly", "id": "GO:0070830", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0070830", "evidence": [ { "database": "UniProtKB", "id": "F6RQM8", "url": "https://www.uniprot.org/uniprotkb/F6RQM8" } ], "pmid": "" }, { "name": "sprouting angiogenesis", "id": "GO:0002040", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0002040", "evidence": [ { "database": "UniProtKB", "id": "F6RQM8", "url": "https://www.uniprot.org/uniprotkb/F6RQM8" } ], "pmid": "" }, { "name": "vascular associated smooth muscle cell development", "id": "GO:0097084", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0097084", "evidence": [ { "database": "UniProtKB", "id": "F6RQM8", "url": "https://www.uniprot.org/uniprotkb/F6RQM8" } ], "pmid": "" }, { "name": "positive regulation of vasculogenesis", "id": "GO:2001214", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:2001214", "evidence": [ { "database": "UniProtKB", "id": "F6RQM8", "url": "https://www.uniprot.org/uniprotkb/F6RQM8" } ], "pmid": "" }, { "name": "cellular response to vascular endothelial growth factor stimulus", "id": "GO:0035924", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0035924", "evidence": [ { "database": "UniProtKB", "id": "F6RQM8", "url": "https://www.uniprot.org/uniprotkb/F6RQM8" } ], "pmid": "" }, { "name": "adherens junction assembly", "id": "GO:0034333", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0034333", "evidence": [ { "database": "UniProtKB", "id": "F6RQM8", "url": "https://www.uniprot.org/uniprotkb/F6RQM8" } ], "pmid": "" }, { "name": "basement membrane assembly", "id": "GO:0070831", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0070831", "evidence": [ { "database": "UniProtKB", "id": "F6RQM8", "url": "https://www.uniprot.org/uniprotkb/F6RQM8" } ], "pmid": "" }, { "name": "adrenomedullin receptor signaling pathway", "id": "GO:1990410", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:1990410", "evidence": [ { "database": "UniProtKB", "id": "F6RQM8", "url": "https://www.uniprot.org/uniprotkb/F6RQM8" } ], "pmid": "" }, { "name": "regulation of G protein-coupled receptor signaling pathway", "id": "GO:0008277", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008277", "evidence": [ { "database": "UniProtKB", "id": "F6RQM8", "url": "https://www.uniprot.org/uniprotkb/F6RQM8" } ], "pmid": "" }, { "name": "amylin receptor 2 signaling pathway", "id": "GO:0150060", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0150060", "evidence": [ { "database": "UniProtKB", "id": "F6RQM8", "url": "https://www.uniprot.org/uniprotkb/F6RQM8" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 3, "go_terms": [ { "name": "cytoplasm", "id": "GO:0005737", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005737", "evidence": [ { "database": "UniProtKB", "id": "F6RQM8", "url": "https://www.uniprot.org/uniprotkb/F6RQM8" } ], "pmid": "" }, { "name": "cell surface", "id": "GO:0009986", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0009986", "evidence": [ { "database": "UniProtKB", "id": "F6RQM8", "url": "https://www.uniprot.org/uniprotkb/F6RQM8" } ], "pmid": "" }, { "name": "adrenomedullin receptor complex", "id": "GO:1903143", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:1903143", "evidence": [ { "database": "UniProtKB", "id": "F6RQM8", "url": "https://www.uniprot.org/uniprotkb/F6RQM8" } ], "pmid": "" } ] }, { "name": "Molecular Function", "total": 3, "go_terms": [ { "name": "coreceptor activity", "id": "GO:0015026", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0015026", "evidence": [ { "database": "UniProtKB", "id": "F6RQM8", "url": "https://www.uniprot.org/uniprotkb/F6RQM8" } ], "pmid": "" }, { "name": "adrenomedullin receptor activity", "id": "GO:0001605", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0001605", "evidence": [ { "database": "UniProtKB", "id": "F6RQM8", "url": "https://www.uniprot.org/uniprotkb/F6RQM8" } ], "pmid": "" }, { "name": "adrenomedullin binding", "id": "GO:1990409", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:1990409", "evidence": [ { "database": "UniProtKB", "id": "F6RQM8", "url": "https://www.uniprot.org/uniprotkb/F6RQM8" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 137, "end_pos": 139, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 137, "end_pos": 139 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": 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"mass": { "chemical_mass": 47475.0, "monoisotopic_mass": 47475.0 }, "refseq": { "ac": "XP_005209028", "name": "perilipin-3 isoform X2", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_005209028" }, "gene_names": [ { "name": "PLIN3", "type": "recommended", "evidence": [ { "id": "F6RMI0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F6RMI0" } ] }, { "name": "M6PRBP1", "type": "synonym", "evidence": [ { "id": "XP_005209028", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_005209028" } ] }, { "name": "PLIN3", "type": "synonym", "evidence": [ { "id": "XP_005209028", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_005209028" } ] } ], "protein_names": [ { "name": "Perilipin", "type": "recommended", "evidence": [ { "id": "F6RMI0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F6RMI0/entry#names_and_taxonomy" } ] }, { "name": "perilipin-3 isoform X2", "type": "synonym", "evidence": [ { "id": "XP_005209028", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_005209028" } ] } ], "function": [ { "annotation": "Lipid droplet-associated protein that maintains the balance between lipogenesis and lipolysis and also regulates fatty acid oxidation in oxidative tissues. Recruits mitochondria to the surface of lipid droplets and is involved in lipid droplet homeostasis by regulating both the storage of fatty acids in the form of triglycerides and the release of fatty acids for mitochondrial fatty acid oxidation. In lipid droplet triacylglycerol hydrolysis, plays a role as a scaffolding protein for three major key lipolytic players: ABHD5, PNPLA2 and LIPE. Reduces the triacylglycerol hydrolase activity of PNPLA2 by recruiting and sequestering PNPLA2 to lipid droplets. Phosphorylation by PKA enables lipolysis probably by promoting release of ABHD5 from the perilipin scaffold and by facilitating interaction of ABHD5 with PNPLA2. Also increases lipolysis through interaction with LIPE and upon PKA-mediated phosphorylation of LIPE.", "evidence": [ { "database": "UniProtKB", "id": "F6RMI0", "url": "https://www.uniprot.org/uniprotkb/F6RMI0#function" }, { "database": "UniProtKB", "id": "ARBA00037149", "url": "https://www.uniprot.org/uniprotkb/ARBA00037149#function" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Bos taurus", "taxid": 9913, "evidence": [ { "database": "UniProtKB", "id": "F6RMI0", "url": "https://www.uniprot.org/uniprotkb/F6RMI0" } ], "common_name": "Bovine", "glygen_name": "Bovine", "reference_species": "Bos taurus [9913]" } ], "gene": [ { "name": "PLIN3", "url": "https://www.uniprot.org/uniprotkb/F6RMI0", "locus": { "chromosome": "7", "start_pos": 19312362, "end_pos": 19291365, "strand": "-", "evidence": [ { "database": "Ensembl Gene", "id": "ENSBTAG00000011805", "url": "https://www.ensembl.org/id/ENSBTAG00000011805" } ] } } ], "crossref": [ { "id": "F6RMI0", "url": "https://alphafold.ebi.ac.uk/entry/F6RMI0", "database": "AlphaFoldDB", "categories": [] }, { "id": "767984", "url": "https://www.ncbi.nlm.nih.gov/gene/767984", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR004279", "url": "https://www.ebi.ac.uk/interpro/entry/IPR004279", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "PTHR14024", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR14024", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR14024:SF11", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR14024:SF11", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF03036", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF03036", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "XP_005209028", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_005209028", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0AAA9STT3", "url": "https://www.uniprot.org/uniprotkb/A0AAA9STT3", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0AAA9STT3-1", "url": "https://www.uniprot.org/uniprotkb/A0AAA9STT3-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0AAA9SVR1", "url": "https://www.uniprot.org/uniprotkb/A0AAA9SVR1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0AAA9SVR1-1", "url": "https://www.uniprot.org/uniprotkb/A0AAA9SVR1-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "F6RMI0", "url": "https://www.uniprot.org/uniprotkb/F6RMI0", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "F6RMI0-1", "url": "https://www.uniprot.org/uniprotkb/F6RMI0-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MSADETEATASTQVTAEEPVQQPSVVDRVAGMPLISSTCNMVTAAYTSTKESYPHVKTVCDAAEKGVKTLTAAAVSGAQPILSKLEPQLTSASEYAHRGLDKLEENLPILQQPPEKVLADTKELVSSKVSGARQAVSSTVSSAKDTVASRVTEAVDVTRGAVQSGVDLTKSMVTSGVHSVVGSRVGQMVLSGVDTVLGKSEEWVDNHLPMTDAELARLATSLEGFDIASVAQQRQEQSYFVRLGSLSERLRQRAYEHSLGKLQNTRQRAQEALHQLSQTLILMETIKQGVDQKLVEGQEKLHQMWLGWNQKRLQGPEENAAKPEVESQTLAMFRDITQQLQTTCASLGSGLQGLPAHIKDQALQARQQVEDLQATFSGIHSFQDLSSSVLTRSREQVARAREALDHLVEYVAQNTPIMWLVGPFAPGIVEKAPEKKK", "length": 437, "header": "tr|F6RMI0-1|F6RMI0_BOVIN Isoform 1 of Perilipin OS=Bos taurus OX=9913 GN=PLIN3 PE=3 SV=1 CANONICAL=F6RMI0-1" }, "isoforms": [ { "isoform_ac": "A0AAA9STT3-1", "url": "https://www.uniprot.org/uniprotkb/A0AAA9STT3/entry", "sequence": { "sequence": "MSADETEATASTQVTAEEPVQQPSVVDRVAGMPLISSTCNMVTAAYTSTKESYPHVKTVCDAAEKGVKTLTAAAVSGAQPILSKLEPQLTSASEYAHRGLDKLEENLPILQQPPEKVLADTKELVSSKVSGARQAVSSTVSSAKDTVASRVTEAVDVTRGAVQSGVDLTKSMVTSGVHSVVGSRVGQMVLSGVDTVLGKSEEWVDNHLPMTDAELARLATSLEGFDIASVAQQRQEQSYFVRLGSLSERLRQRAYEHSLGKLQNTRQRAQEALHQLSQTLILMETIKQGVDQKLVEGQEKLHQMWLGWNQKRLQGPEENAAKPEQVESQTLAMFRDITQQLQTTCASLGSGLQGLPAHIKDQALQARQQQLNNSGVSVWPSWAVGVFHLPPTHLPESCPGCYVPGSQRKGEAHRFSCTGPSQACRGTL", "length": 428, "header": "tr|A0AAA9STT3-1|F6RMI0_BOVIN Computationally mapped isoform of Perilipin OS=Bos taurus OX=9913 GN=PLIN3 PE=3 SV=1 CANONICAL=F6RMI0-1" }, "locus": { "chromosome": "7", "start_pos": 19312124, "end_pos": 19294571, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000125047.2", "url": "https://www.ensembl.org/id/ENSBTAT00000125047.2" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000089833.1", "url": "https://www.ensembl.org/id/ENSBTAP00000089833.1" } ] } }, { "isoform_ac": "A0AAA9SVR1-1", "url": "https://www.uniprot.org/uniprotkb/A0AAA9SVR1/entry", "sequence": { "sequence": "MSADETEATASTQVTAEEPVQQPSVVDRVAGMPLISSTCNMVTAAYTSTKESYPHVKTVCDAAEKGVKTLTAAAVSGAQPILSKLEPQLTSASEYAHRGLDKLEENLPILQQPPEKVLADTKELVSSKVSGARQAVSSTVSSAKDTVASRVTEAVDVTRGAVQSGVDLTKSMVTSGVHSVVGSRVGQMVLSGVDTVLGKSEEWVDNHLPMTDAELARLATSLEGFDIASVAQQRQEQSYFVRLGSLSERLRQRAYEHSLGKLQNTRQRAQEALHQLSQTLILMETIKQGVDQKLVEGQEKLHQMWLGWNQKRLQGPEENAAKPEDLMTTPPGCLPGFLLLESYTMWPSVSGFKVHPRGSKCQGCTPSYGARTWRRANEPHFVSPFASRWAFGLFPLSAAVNNTPLSICVPVLAQTCVFFSLGRKSRGWNC", "length": 430, "header": "tr|A0AAA9SVR1-1|F6RMI0_BOVIN Computationally mapped isoform of Perilipin OS=Bos taurus OX=9913 GN=PLIN3 PE=3 SV=1 CANONICAL=F6RMI0-1" }, "locus": { "chromosome": "7", "start_pos": 19309948, "end_pos": 19294571, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000132848.2", "url": "https://www.ensembl.org/id/ENSBTAT00000132848.2" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000087268.1", "url": "https://www.ensembl.org/id/ENSBTAP00000087268.1" } ] } }, { "isoform_ac": "F6RMI0-1", "url": "https://www.uniprot.org/uniprotkb/F6RMI0/entry", "sequence": { "sequence": "MSADETEATASTQVTAEEPVQQPSVVDRVAGMPLISSTCNMVTAAYTSTKESYPHVKTVCDAAEKGVKTLTAAAVSGAQPILSKLEPQLTSASEYAHRGLDKLEENLPILQQPPEKVLADTKELVSSKVSGARQAVSSTVSSAKDTVASRVTEAVDVTRGAVQSGVDLTKSMVTSGVHSVVGSRVGQMVLSGVDTVLGKSEEWVDNHLPMTDAELARLATSLEGFDIASVAQQRQEQSYFVRLGSLSERLRQRAYEHSLGKLQNTRQRAQEALHQLSQTLILMETIKQGVDQKLVEGQEKLHQMWLGWNQKRLQGPEENAAKPEVESQTLAMFRDITQQLQTTCASLGSGLQGLPAHIKDQALQARQQVEDLQATFSGIHSFQDLSSSVLTRSREQVARAREALDHLVEYVAQNTPIMWLVGPFAPGIVEKAPEKKK", "length": 437, "header": "tr|F6RMI0-1|F6RMI0_BOVIN Isoform 1 of Perilipin OS=Bos taurus OX=9913 GN=PLIN3 PE=3 SV=1 CANONICAL=F6RMI0-1" }, "locus": { "chromosome": "7", "start_pos": 19311425, "end_pos": 19294571, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000015669.8", "url": "https://www.ensembl.org/id/ENSBTAT00000015669.8" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000015669.6", "url": "https://www.ensembl.org/id/ENSBTAP00000015669.6" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [], "orthologs": [], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 2, "go_terms": [ { "name": "lipid droplet", "id": "GO:0005811", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005811", "evidence": [ { "database": "UniProtKB", "id": "F6RMI0", "url": "https://www.uniprot.org/uniprotkb/F6RMI0" } ], "pmid": "" }, { "name": "mitochondrion", "id": "GO:0005739", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005739", "evidence": [ { "database": "UniProtKB", "id": "F6RMI0", "url": "https://www.uniprot.org/uniprotkb/F6RMI0" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 3, "go_terms": [ { "name": "cellular response to glucose starvation", "id": "GO:0042149", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0042149", "evidence": [ { "database": "UniProtKB", "id": "F6RMI0", "url": "https://www.uniprot.org/uniprotkb/F6RMI0" } ], "pmid": "" }, { "name": "lipid storage", "id": "GO:0019915", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0019915", "evidence": [ { "database": "UniProtKB", "id": "F6RMI0", "url": "https://www.uniprot.org/uniprotkb/F6RMI0" } ], "pmid": "" }, { "name": "lipid droplet disassembly", "id": "GO:1905691", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:1905691", "evidence": [ { "database": "UniProtKB", "id": "F6RMI0", "url": "https://www.uniprot.org/uniprotkb/F6RMI0" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ], "tool_support": { "graph_view": "yes" } }, { "uniprot_canonical_ac": "F6RWG1-1", "uniprot_ac": "F6RWG1", "uniprot_id": "F6RWG1_BOVIN", "mass": { "chemical_mass": 71557.0, "monoisotopic_mass": 71557.0 }, "refseq": { "ac": "XP_002692179", "name": "zinc finger protein 133 isoform X2", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_002692179" }, "gene_names": [ { "name": "LOC539166", "type": "recommended", "evidence": [ { "id": "F6RWG1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F6RWG1" } ] }, { "name": "LOC539166", "type": "synonym", "evidence": [ { "id": "XP_002692179", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_002692179" } ] } ], "protein_names": [ { "name": "Zinc finger protein 133", "type": "recommended", "evidence": [ { "id": "F6RWG1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F6RWG1/entry#names_and_taxonomy" } ] }, { "name": "zinc finger protein 133 isoform X2", "type": "synonym", "evidence": [ { "id": "XP_002692179", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_002692179" } ] } ], "function": [ { "annotation": "May be involved in transcriptional regulation.", "evidence": [ { "database": "UniProtKB", "id": "A0AAA9SZY0", "url": "https://www.uniprot.org/uniprotkb/A0AAA9SZY0#function" }, { "database": "UniProtKB", "id": "ARBA00003767", "url": "https://www.uniprot.org/uniprotkb/ARBA00003767#function" }, { "database": "UniProtKB", "id": "F6RWG1", "url": "https://www.uniprot.org/uniprotkb/F6RWG1#function" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Bos taurus", "taxid": 9913, "evidence": [ { "database": "UniProtKB", "id": "F6RWG1", "url": "https://www.uniprot.org/uniprotkb/F6RWG1" } ], "common_name": "Bovine", "glygen_name": "Bovine", "reference_species": "Bos taurus [9913]" } ], "gene": [ { "name": "LOC539166", "url": "https://www.uniprot.org/uniprotkb/F6RWG1", "locus": {} } ], "crossref": [ { "id": "F6RWG1", "url": "https://alphafold.ebi.ac.uk/entry/F6RWG1", "database": "AlphaFoldDB", "categories": [] }, { "id": "cd07765", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd07765", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "539166", "url": "https://www.ncbi.nlm.nih.gov/gene/539166", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR001909", "url": "https://www.ebi.ac.uk/interpro/entry/IPR001909", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR013087", "url": "https://www.ebi.ac.uk/interpro/entry/IPR013087", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR036051", "url": "https://www.ebi.ac.uk/interpro/entry/IPR036051", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR036236", "url": "https://www.ebi.ac.uk/interpro/entry/IPR036236", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "bta:539166", "url": "https://www.genome.jp/dbget-bin/www_bget?bta:539166", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "QKFHMQH", "url": "https://omabrowser.org/oma/group/QKFHMQH/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "PTHR14003", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR14003", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR14003:SF23", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR14003:SF23", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00096", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00096", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF01352", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF01352", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "XP_002692179", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_002692179", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0AAA9SZY0", "url": "https://www.uniprot.org/uniprotkb/A0AAA9SZY0", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0AAA9SZY0-1", "url": "https://www.uniprot.org/uniprotkb/A0AAA9SZY0-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "F6RWG1", "url": "https://www.uniprot.org/uniprotkb/F6RWG1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "F6RWG1-1", "url": "https://www.uniprot.org/uniprotkb/F6RWG1-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MAFRDVAVDFTQDEWVLLSPAQRSLYREVMLENYSNLVSLGIPFSKPELITQLEQGKETWREERKCSPVSCLEPKPELHLCPFCPPDLCSQKFHMQQVLCSPPPWIFTCLYAEDPVQPGDLCLEDQQQQAAGGSAWIEEVEGQEGEGARPLFGKTEKSTVEAFPRPPQRQPVISGGGVPGMEIEAGPAQMGTPEETDRLLKRIEVLGFGTVNCGECGLGFSKKTNLLSHQRIHSREKPYVCGVCGKGFSLKRSLDGHQNAHSGEKPLVCGECGRGFKQRSKLIIHERRHSGEKPYMCGECGRGFSDKSNLIVHQRTHSGEKPYVCQECGKGFSQKSAVIRHQTTHLKEKTVVCGNCGLGFSDRSNLIKHQRTHTREKPYACKECGWCFRQRSTLVNHQRTHSKEKPYVCGVCGHRFSQNSTLISHRRTHTGEKPYVCGVCGRGFSLKSHLNRHQNTHSGHKPIVCKDCGRVFSQQSNLIRHQRTHSGEKPLVCVECGRGFSQKSNLVEHQRTHSGEKPYVCRECGRGFRHQSALIRHCSTHTREQPFNCRRCGRGFGNKSALLMHKWSHLEENSFLCTECGQGFSHKKHLILHQMTHQGRTPHMCKGCGQGFIQKSHLNRHRRNVCRPQNTISV", "length": 634, "header": "tr|F6RWG1-1|F6RWG1_BOVIN Isoform 1 of Zinc finger protein 133 OS=Bos taurus OX=9913 GN=LOC539166 PE=3 SV=1 CANONICAL=F6RWG1-1" }, "isoforms": [ { "isoform_ac": "A0AAA9SZY0-1", "url": "https://www.uniprot.org/uniprotkb/A0AAA9SZY0/entry", "sequence": { "sequence": "MAFRDVAVDFTQDEWVLLSPAQRSLYREVMLENYSNLVSLELITQLEQGKETWREERKCSPVSCLEPKPELHLCPFCPPDLCSQKFHMQQVLCSPPPWIFTCLYAEDPVQPGDLCLEDQQQQAAGGSAWIEEVEGQEGEGARPLFGKTEKSTVEAFPRPPQRQPVISGGGVPGMEIEAGPAQMGTPEETDRLLKRIEVLGFGTVNCGECGLGFSKKTNLLSHQRIHSREKPYVCGVCGKGFSLKRSLDGHQNAHSGEKPLVCGECGRGFKQRSKLIIHERRHSGEKPYMCGECGRGFSDKSNLIVHQRTHSGEKPYVCQECGKGFSQKSAVIRHQTTHLKEKTVVCGNCGLGFSDRSNLIKHQRTHTREKPYACKECGWCFRQRSTLVNHQRTHSKEKPYVCGVCGHRFSQNSTLISHRRTHTGEKPYVCGVCGRGFSLKSHLNRHQNTHSGHKPIVCKDCGRVFSQQSNLIRHQRTHSGEKPLVCVECGRGFSQKSNLVEHQRTHSGEKPYVCRECGRGFRHQSALIRHCSTHTREQPFNCRRCGRGFGNKSALLMHKWSHLEENSFLCTECGQGFSHKKHLILHQMTHQGRTPHMCKGCGQGFIQKSHLNRHRRNVCRPQNTISV", "length": 627, "header": "tr|A0AAA9SZY0-1|F6RWG1_BOVIN Computationally mapped isoform of Zinc finger protein 133 OS=Bos taurus OX=9913 GN=LOC539166 PE=3 SV=1 CANONICAL=F6RWG1-1" }, "locus": { "chromosome": "13", "start_pos": 38470966, "end_pos": 38464007, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000109292.2", "url": "https://www.ensembl.org/id/ENSBTAT00000109292.2" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000089840.1", "url": "https://www.ensembl.org/id/ENSBTAP00000089840.1" } ] } }, { "isoform_ac": "F6RWG1-1", "url": "https://www.uniprot.org/uniprotkb/F6RWG1/entry", "sequence": { "sequence": "MAFRDVAVDFTQDEWVLLSPAQRSLYREVMLENYSNLVSLGIPFSKPELITQLEQGKETWREERKCSPVSCLEPKPELHLCPFCPPDLCSQKFHMQQVLCSPPPWIFTCLYAEDPVQPGDLCLEDQQQQAAGGSAWIEEVEGQEGEGARPLFGKTEKSTVEAFPRPPQRQPVISGGGVPGMEIEAGPAQMGTPEETDRLLKRIEVLGFGTVNCGECGLGFSKKTNLLSHQRIHSREKPYVCGVCGKGFSLKRSLDGHQNAHSGEKPLVCGECGRGFKQRSKLIIHERRHSGEKPYMCGECGRGFSDKSNLIVHQRTHSGEKPYVCQECGKGFSQKSAVIRHQTTHLKEKTVVCGNCGLGFSDRSNLIKHQRTHTREKPYACKECGWCFRQRSTLVNHQRTHSKEKPYVCGVCGHRFSQNSTLISHRRTHTGEKPYVCGVCGRGFSLKSHLNRHQNTHSGHKPIVCKDCGRVFSQQSNLIRHQRTHSGEKPLVCVECGRGFSQKSNLVEHQRTHSGEKPYVCRECGRGFRHQSALIRHCSTHTREQPFNCRRCGRGFGNKSALLMHKWSHLEENSFLCTECGQGFSHKKHLILHQMTHQGRTPHMCKGCGQGFIQKSHLNRHRRNVCRPQNTISV", "length": 634, "header": "tr|F6RWG1-1|F6RWG1_BOVIN Isoform 1 of Zinc finger protein 133 OS=Bos taurus OX=9913 GN=LOC539166 PE=3 SV=1 CANONICAL=F6RWG1-1" }, "locus": { "chromosome": "13", "start_pos": 38470966, "end_pos": 38464007, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000039401.7", "url": "https://www.ensembl.org/id/ENSBTAT00000039401.7" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000039195.5", "url": "https://www.ensembl.org/id/ENSBTAP00000039195.5" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [ { "id": "bta:539166", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?bta:539166", "resource": "KEGG Pathway" } ], "orthologs": [ { "uniprot_canonical_ac": "F7FQD8-1", "protein_name": "Zinc finger protein 133", "gene_name": "Zfp133", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MGAAVPPRTAGGRGACWKVHMAFRDVAVDFSQEEWSLLSPAQRSLYREVMLENYSNLVSLGIPFSKPKLITQLEQGKETWREERKCPQVACPAQAKLELCPGHVCPPDLTNQKSPVQHVLSHHAPLIFTCLCAESHVDRGDSCQGALEKQHQASDKNSCRDKSEGGERESARPSSGRTKKGSLGALSRPPQGQPVNSPNGIRWVEMETSPAQARSTEEPEKLLKGIEILEFGTVNCEECGLGFSKMTNLLSHQRIHSGEKPYVCGVCEKGFSLKKSLARHQKAHSGEKPIVCKECWRGFSRKSTLIIHERTHSGEKPYMCSECGRGFSQKSNLIIHQRTHSGEKPYVCRECGKGFSQKSAVVRHESTHLEEKTFLCSDCGLGFSDRSNFISHQRTHSGEKPYACKECGQCFRQRTTLVNHQRTHSKEKPYVCGICGHSFSQNSTLISHRRMHTGEKPYVCGVCGRGFSLKSHLNRHQNIHSGEKPIVCKDCGRGFSQQSNLIRHQRTHSGEKPIVCEECGRGFSQKSNLIAHQRTHSGEKPRVC", "length": 544 }, "evidence": [ { "id": "F6RWG1", "url": "https://omabrowser.org/oma/group/F6RWG1/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "G3GVW4-1", "protein_name": "Zinc finger protein 133", "gene_name": "Znf133", "tax_id": 10029, "organism": "Cricetulus griseus", "sequence": { "sequence": "MAFRDVAVDFSQEEWSLLSPAQRSLYREVMLENYSNLVSLGIPFSKPKLITQLEQGKETWQEERKCPQVACQAQAKLELCPSPVCPPDPTNQKLPGQHGLSDRTPWIFTCLCAKHHVDEGDSCHGAQEEQQQASNRNSCRDKPEGGEREGARPSSRRIKKRSLGALSRAPQRQPVSSRNGISRVGMEASPAQAGSTEEPEKLLKQIEFLGFGTVNCGECGLGFRKMTNLLSHQRIHSGEKPYVCGVCEKGFSLKKSLARHQKAHSEEKPIVCRECGRGFNRKSTLIIHERTHSGEKPYTCSECGRGFSQKSNLIIHRRTHSGEKPYVCRECGKGFSQKSAVVRHQRTHLEEKSIVCSDCGLGFSDRSNLISHQRTHSGAKPYACKECGQCFRQRTTLVNHQRTHSKEKPYVCGVCGHSFSQNSTLISHRRTHTGEKPFVCGVCGRRFSLKSHLNRHQNIHSGEKPIVCKDCGRGFSQQSNLIRHQRTHSGEKPMVCEECGRGFSQKSNLIAHQRIHSGEKPYVCRDCGRGFSHQAGLIRHKRKHSREKPYVCRQCGLGFTNKPALITHKRAHFEERLCVCGECGQSFIHKSHLALHQTTHQREKTYTCRTCGQGFRQRSHLSRHRKKKCAHHKLPLQPDPEACLGQSSDPFYSL", "length": 654 }, "evidence": [ { "id": "F6RWG1", "url": "https://omabrowser.org/oma/group/F6RWG1/", "database": "OMA" } ], "glygen_name": "Hamster", "common_name": "Chinese hamster" }, { "uniprot_canonical_ac": "P52736-1", "protein_name": "Zinc finger protein 133", "gene_name": "ZNF133", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MAFRDVAVDFTQDEWRLLSPAQRTLYREVMLENYSNLVSLGISFSKPELITQLEQGKETWREEKKCSPATCPADPEPELYLDPFCPPGFSSQKFPMQHVLCNHPPWIFTCLCAEGNIQPGDPGPGDQEKQQQASEGRPWSDQAEGPEGEGAMPLFGRTKKRTLGAFSRPPQRQPVSSRNGLRGVELEASPAQSGNPEETDKLLKRIEVLGFGTVNCGECGLSFSKMTNLLSHQRIHSGEKPYVCGVCEKGFSLKKSLARHQKAHSGEKPIVCRECGRGFNRKSTLIIHERTHSGEKPYMCSECGRGFSQKSNLIIHQRTHSGEKPYVCRECGKGFSQKSAVVRHQRTHLEEKTIVCSDCGLGFSDRSNLISHQRTHSGEKPYACKECGRCFRQRTTLVNHQRTHSKEKPYVCGVCGHSFSQNSTLISHRRTHTGEKPYVCGVCGRGFSLKSHLNRHQNIHSGEKPIVCKDCGRGFSQQSNLIRHQRTHSGEKPMVCGECGRGFSQKSNLVAHQRTHSGERPYVCRECGRGFSHQAGLIRHKRKHSREKPYMCRQCGLGFGNKSALITHKRAHSEEKPCVCRECGQGFLQKSHLTLHQMTHTGEKPYVCKTCGRGFSLKSHLSRHRKTTSVHHRLPVQPDPEPCAGQPSDSLYSL", "length": 654 }, "evidence": [ { "id": "F6RWG1", "url": "https://omabrowser.org/oma/group/F6RWG1/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" } ], "go_annotation": { "categories": [ { "name": "Molecular Function", "total": 3, "go_terms": [ { "name": "DNA-binding transcription factor activity", "id": "GO:0003700", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003700", "evidence": [ { "database": "UniProtKB", "id": "F6RWG1", "url": "https://www.uniprot.org/uniprotkb/F6RWG1" } ], "pmid": "" }, { "name": "zinc ion binding", "id": "GO:0008270", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008270", "evidence": [ { "database": "UniProtKB", "id": "F6RWG1", "url": "https://www.uniprot.org/uniprotkb/F6RWG1" } ], "pmid": "" }, { "name": "sequence-specific DNA binding", "id": "GO:0043565", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0043565", "evidence": [ { "database": "UniProtKB", "id": "F6RWG1", "url": "https://www.uniprot.org/uniprotkb/F6RWG1" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 1, "go_terms": [ { "name": "nucleus", "id": "GO:0005634", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005634", "evidence": [ { "database": "UniProtKB", "id": "F6RWG1", "url": "https://www.uniprot.org/uniprotkb/F6RWG1" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 2, "go_terms": [ { "name": "DNA-templated transcription", "id": "GO:0006351", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006351", "evidence": [ { "database": "UniProtKB", "id": "F6RWG1", "url": "https://www.uniprot.org/uniprotkb/F6RWG1" } ], "pmid": "" }, { "name": "negative regulation of DNA-templated transcription", "id": "GO:0045892", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0045892", "evidence": [ { "database": "UniProtKB", "id": "F6RWG1", "url": "https://www.uniprot.org/uniprotkb/F6RWG1" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 33, "end_pos": 35, "annotation": "n_glycosylation_sequon" }, { "start_pos": 419, "end_pos": 421, "annotation": "n_glycosylation_sequon" }, { "start_pos": 558, "end_pos": 560, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "F6RWG1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F6RWG1" }, { "id": "PS50157", "database": "PROSITE", "url": "https://prosite.expasy.org/PS50157" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "C2H2-type", "eco_id": "ECO_0000259", "start_pos": 211, "end_pos": 238, "start_aa": "Val", "end_aa": "Pro", "glycosite_overlap": [] }, { "evidence": [ { "id": "F6RWG1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F6RWG1" }, { "id": "PS50805", "database": "PROSITE", "url": "https://prosite.expasy.org/PS50805" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "KRAB", "eco_id": "ECO_0000259", "start_pos": 1, "end_pos": 72, "start_aa": "Met", "end_aa": "Leu", "glycosite_overlap": [] } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" }, { "name": "homologset.oma", "label": "OMA Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 33, "end_pos": 35 }, { "start_pos": 419, "end_pos": 421 }, { "start_pos": 558, "end_pos": 560 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ], "tool_support": { "graph_view": "yes" } }, { "uniprot_canonical_ac": "G5E5A3-1", "uniprot_ac": "G5E5A3", "uniprot_id": "G5E5A3_BOVIN", "mass": { "chemical_mass": 172744.0, "monoisotopic_mass": 172744.0 }, "refseq": { "ac": "XP_003586209", "name": "EF-hand calcium-binding domain-containing protein 6 isoform X1", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_003586209" }, "gene_names": [ { "name": "EFCAB6", "type": "recommended", "evidence": [ { "id": "G5E5A3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G5E5A3" } ] }, { "name": "EFCAB6", "type": "synonym", "evidence": [ { "id": "XP_003586209", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_003586209" } ] } ], "protein_names": [ { "name": "EF-hand calcium-binding domain-containing protein 6", "type": "recommended", "evidence": [ { "id": "G5E5A3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G5E5A3/entry#names_and_taxonomy" } ] }, { "name": "DJ-1-binding protein", "type": "synonym", "evidence": [ { "id": "G5E5A3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G5E5A3/entry#names_and_taxonomy" } ] }, { "name": "EF-hand calcium-binding domain-containing protein 6 isoform X1", "type": "synonym", "evidence": [ { "id": "XP_003586209", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_003586209" } ] } ], "function": [ { "annotation": "Negatively regulates the androgen receptor by recruiting histone deacetylase complex, and protein DJ-1 antagonizes this inhibition by abrogation of this complex. Microtubule inner protein (MIP) part of the dynein-decorated doublet microtubules (DMTs) in cilia axoneme, which is required for motile cilia beating.", "evidence": [ { "database": "UniProtKB", "id": "G5E5A3", "url": "https://www.uniprot.org/uniprotkb/G5E5A3#function" }, { "database": "UniProtKB", "id": "ARBA00054968", "url": "https://www.uniprot.org/uniprotkb/ARBA00054968#function" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Bos taurus", "taxid": 9913, "evidence": [ { "database": "UniProtKB", "id": "G5E5A3", "url": "https://www.uniprot.org/uniprotkb/G5E5A3" } ], "common_name": "Bovine", "glygen_name": "Bovine", "reference_species": "Bos taurus [9913]" } ], "gene": [ { "name": "EFCAB6", "url": "https://www.uniprot.org/uniprotkb/G5E5A3", "locus": { "chromosome": "5", "start_pos": 114257682, "end_pos": 114490963, "strand": "+", "evidence": [ { "database": "Ensembl Gene", "id": "ENSBTAG00000030189", "url": "https://www.ensembl.org/id/ENSBTAG00000030189" } ] } } ], "crossref": [ { "id": "ENSBTAG00000030189", "url": "https://bgee.org/?page=gene&gene_id=ENSBTAG00000030189", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "ENSBTAG00000053264", "url": "https://bgee.org/?page=gene&gene_id=ENSBTAG00000053264", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "535401", "url": "https://www.ncbi.nlm.nih.gov/gene/535401", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "8OTZ", "url": "https://www.ncbi.nlm.nih.gov/Structure/icn3d/?mmdbid=8OTZ&bu=0", "database": "iCn3D", "categories": [ "3D Structure" ] }, { "id": "9CPB", "url": "https://www.ncbi.nlm.nih.gov/Structure/icn3d/?mmdbid=9CPB&bu=0", "database": "iCn3D", "categories": [ "3D Structure" ] }, { "id": "9FQR", "url": "https://www.ncbi.nlm.nih.gov/Structure/icn3d/?mmdbid=9FQR&bu=0", "database": "iCn3D", "categories": [ "3D Structure" ] }, { "id": "IPR002048", "url": "https://www.ebi.ac.uk/interpro/entry/IPR002048", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR011992", "url": "https://www.ebi.ac.uk/interpro/entry/IPR011992", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR015070", "url": "https://www.ebi.ac.uk/interpro/entry/IPR015070", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR018247", "url": "https://www.ebi.ac.uk/interpro/entry/IPR018247", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR052603", "url": "https://www.ebi.ac.uk/interpro/entry/IPR052603", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "bta:535401", "url": "https://www.genome.jp/dbget-bin/www_bget?bta:535401", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "PTHR20875", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR20875", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR20875:SF2", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR20875:SF2", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "pdb_00008otz", "url": "https://www.rcsb.org/structure/pdb_00008otz", "database": "PDB", "categories": [ "3D Structure" ] }, { "id": "pdb_00009cpb", "url": "https://www.rcsb.org/structure/pdb_00009cpb", "database": "PDB", "categories": [ "3D Structure" ] }, { "id": "pdb_00009fqr", "url": "https://www.rcsb.org/structure/pdb_00009fqr", "database": "PDB", "categories": [ "3D Structure" ] }, { "id": "8OTZ", "url": "https://www.rcsb.org/structure/8OTZ", "database": "PDB", "categories": [ "3D Structure" ] }, { "id": "9CPB", "url": "https://www.rcsb.org/structure/9CPB", "database": "PDB", "categories": [ "3D Structure" ] }, { "id": "9FQR", "url": "https://www.rcsb.org/structure/9FQR", "database": "PDB", "categories": [ "3D Structure" ] }, { "id": "PF08976", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF08976", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF13499", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF13499", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF13833", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF13833", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "XP_003586209", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_003586209", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0AAA9T3G9", "url": "https://www.uniprot.org/uniprotkb/A0AAA9T3G9", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0AAA9T3G9-1", "url": "https://www.uniprot.org/uniprotkb/A0AAA9T3G9-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "G3X7P6", "url": "https://www.uniprot.org/uniprotkb/G3X7P6", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "G3X7P6-1", "url": "https://www.uniprot.org/uniprotkb/G3X7P6-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "G5E5A3", "url": "https://www.uniprot.org/uniprotkb/G5E5A3", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "G5E5A3-1", "url": "https://www.uniprot.org/uniprotkb/G5E5A3-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MCKMAVVPDWHIICPYTRKFTHSRPHSSPCRVYSRSVFQNMFRPSSSTTVANPILSSLDVKRILFQKITEKGDELKRAFHLLDTANNMTVTKSELRRVITTFLLPLTREQFQDVLAQIPLTSSGAVPYLVFLSRFGGIDLNINVIKRGGENEMNGCRTLKDLEAQVGEKIFKNIKTVIKALMLIDVNTTGLVQPHELRRVLETFCLKMKDEEYKKFAQHYNIDKDAAVDYNVFLKNLGSNNDLNLKYNMGSQEVLWENQRVKSFKREEPPSSAVSDNIWKNYSLDEIETAFCLELSKCYEKVEKALSAGDPCTSGYVSLNYLKIVLDTFVYRLPRRIFIQLMKRFGLKTTTKVNWKQFLTSFYEPQYEASSKAPLTKRNSINFRNQVHKENVITKLFRHEDHDSSLKKALLLIKSKPDGQITGQELQRILNCMVVKISDSEFRELMRILDPGCTGCVNVSRFIELIEESPKLHKIPAYKDTKMPLFLAWDSVEEIIHDSIAKNLSAFCNMLRSYDLGDTGLIGRNNFKKIMRVFCPFLTTEHLVKLCSKFQDIASGRILYKKLLACLGINRPPTVSPVSMPKGQLLNEHLQKEEQPLPDHSERATPAESQGAVTRNMTKDEVIEKLKSCIQQQDPAFRKRFLDFTKEPNGKIHTHDFKKVLEDYGMPMDDDQYALLTTKLGYKKEGMSYLDFAAGFEDPKMNEPEVTPPQTPVLPKGDVDSFFVTAEECLRQFPRRLKEFFRDPYAAFFKMDTDRDGILTMHDLHRLLQHLLFNLKDEEFERLLGLLGLRLSITLNFREFRNLCEKRSFSADDDAPQRLPRPKQKVADSELACEQAHQYLVTKAKTRWSDLSKNFIETDSEGNGILRRRDMKNALYGFDIPLTPREFEKLWMRYDSEGRGHITYQEFLQKLGINYSADIHRPYAEEYFNFMGHFTKPQQVQEELKELQQSTEKAMPARDKLKDHDQDISKALAKLDKSRTGYISLGRLQRLLQECGCSLKEEELIDLLNSWGIAWHNNSINYLDFLRAVENNKLTRPQSQEKEESVPINFAALSPEEVLKNIQGVIAASSLALSTAFSALDKEDTGFVKASDFGQVLKDFCYKLTDNQYHYFLRKLRLHLTPYINWKYFLQNFSSYVEETAVEWAEKMPRGPRPLSPKEMANQELLARLHKAVTSHYHAIAQEFENFDTMKTNTASRDEFRSICTRHVQVLTDEQFDRLWEEMPVNSKGRLRYLDFLSSFNVDKQATPLATSDSAKAQRGSSVPEVSDRGRSAGSSPTRDPKAGSKPRSHPCTPSSVSGTPPLQNCEPIETKLRKKVQGCWRELLRECKERDFNKQGEIPGPEFLALVEKFNLDISRDECQQLLIKYDLKNNGKFAYCSFIQSCVLLLKAKETSLMQRMKIQNANKMKEAGAETCSFYSALLRIQPKIVHCWRPMRRTFKAYDEGGTGLLSVADFRKVLRQYSINLSEEEFFHILEYYDKTLSSKISYNDFLRAFLQ", "length": 1497, "header": "tr|G5E5A3-1|G5E5A3_BOVIN Isoform 1 of EF-hand calcium-binding domain-containing protein 6 OS=Bos taurus OX=9913 GN=EFCAB6 PE=1 SV=4 CANONICAL=G5E5A3-1" }, "isoforms": [ { "isoform_ac": "A0AAA9T3G9-1", "url": "https://www.uniprot.org/uniprotkb/A0AAA9T3G9/entry", "sequence": { "sequence": "VFSKICSDLLHIPLTSSGAVPYLVFLSRFGGIDLNINVIKRGGENEMNGCRTLKDLEAQVGEKIFKNIKTVIKALMLIDVNTTGLVQPHELRRVLETFCLKMKDEEYKKFAQHYNIDKDAAVDYNVFLKNLGSNNDLNLKYNMGSQEVLWENQRVKSFKREEPPSSAVSDNIWKNYSLDEIETAFCLEVRFFPRPGLSKL", "length": 200, "header": "tr|A0AAA9T3G9-1|G5E5A3_BOVIN Computationally mapped isoform of EF-hand calcium-binding domain-containing protein 6 OS=Bos taurus OX=9913 GN=EFCAB6 PE=1 SV=1 CANONICAL=G5E5A3-1" }, "locus": { "chromosome": "5", "start_pos": 114490850, "end_pos": 114424686, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000134071.1", "url": "https://www.ensembl.org/id/ENSBTAT00000134071.1" }, { "database": "Ensembl Peptide", "id": 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"Ensembl Peptide", "id": "ENSBTAP00000040233.3", "url": "https://www.ensembl.org/id/ENSBTAP00000040233.3" } ] } }, { "isoform_ac": "G5E5A3-1", "url": "https://www.uniprot.org/uniprotkb/G5E5A3/entry", "sequence": { "sequence": 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"tr|F6RMV5-1|F6RMV5_BOVIN Isoform 1 of Leucine rich alpha-2-glycoprotein 1 OS=Bos taurus OX=9913 GN=LRG1 PE=1 SV=1 CANONICAL=F6RMV5-1" }, "isoforms": [ { "isoform_ac": "A0AAA9SYF1-1", "url": "https://www.uniprot.org/uniprotkb/A0AAA9SYF1/entry", "sequence": { "sequence": "SSERLLQRGRGGSLVGWDSHLSRIFLLLLFVVSAQGLTPNPEACLVFSSVNGSSISCQPPAQIPHSLPADTIFLAVEFFNLTQLPADFLQGVPNLQELHLSSNRLEDFSPKFLLPVPQLKVLDLTRNSLTGLFPGFFRVSAALCTLVLKGNQLKFLEASWLHGLKALRHLDLSENQLHSLPPGLLENFTDLLTLDLSNNQLQTLPPDLLRGPLNLERLHLEGNRLQVLGEGLLAPQPKLRYLFLNDNRLASVAAGAFRGLQKLDMLDLSNNLLTTVPTGLWTSLGKAARNLKDGFDISNNPWICDQNLADLYRWLVANENKMFFRNHTRCAGPEALKGQTLLAAAESH", "length": 348, "header": "tr|A0AAA9SYF1-1|F6RMV5_BOVIN Computationally mapped isoform of Leucine rich alpha-2-glycoprotein 1 OS=Bos taurus OX=9913 GN=LRG1 PE=1 SV=1 CANONICAL=F6RMV5-1" }, "locus": { "chromosome": "7", "start_pos": 19598679, "end_pos": 19596621, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000134044.1", "url": "https://www.ensembl.org/id/ENSBTAT00000134044.1" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000090394.1", "url": "https://www.ensembl.org/id/ENSBTAP00000090394.1" } ] } }, { "isoform_ac": "A0AAA9TBW3-1", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TBW3/entry", "sequence": { "sequence": "MNKSLWALPSKHGTREIRNDPENNLVGWDSHLSRIFLLLLFVVSAQGLTPNPEACLVFSSVNGSSISCQPPAQIPHSLPADTIFLAVEFFNLTQLPADFLQGVPNLQELHLSSNRLEDFSPKFLLPVPQLKVLDLTRNSLTGLFPGFFRVSAALCTLVLKGNQLKFLEASWLHGLKALRHLDLSENQLHSLPPGLLENFTDLLTLDLSNNQLQTLPPDLLRGPLNLERLHLEGNRLQVLGEGLLAPQPKLRYLFLNDNRLASVAAGAFRGLQKLDMLDLSNNLLTTVPTGLWTSLGKAARNLKDGFDISNNPWICDQNLADLYRWLVANENKMFFRNHTRCAGPEALKGQTLLAAAESH", "length": 359, "header": "tr|A0AAA9TBW3-1|F6RMV5_BOVIN Computationally mapped isoform of Leucine rich alpha-2-glycoprotein 1 OS=Bos taurus OX=9913 GN=LRG1 PE=1 SV=1 CANONICAL=F6RMV5-1" }, "locus": { "chromosome": "7", "start_pos": 19598679, "end_pos": 19597247, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000131468.1", "url": "https://www.ensembl.org/id/ENSBTAT00000131468.1" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000094174.1", "url": "https://www.ensembl.org/id/ENSBTAP00000094174.1" } ] } }, { "isoform_ac": "F6RMV5-1", "url": "https://www.uniprot.org/uniprotkb/F6RMV5/entry", "sequence": { "sequence": "MKKREATMSSQNPERKQSLVGWDSHLSRIFLLLLFVVSAQGLTPNPEACLVFSSVNGSSISCQPPAQIPHSLPADTIFLAVEFFNLTQLPADFLQGVPNLQELHLSSNRLEDFSPKFLLPVPQLKVLDLTRNSLTGLFPGFFRVSAALCTLVLKGNQLKFLEASWLHGLKALRHLDLSENQLHSLPPGLLENFTDLLTLDLSNNQLQTLPPDLLRGPLNLERLHLEGNRLQVLGEGLLAPQPKLRYLFLNDNRLASVAAGAFRGLQKLDMLDLSNNLLTTVPTGLWTSLGKAARNLKDGFDISNNPWICDQNLADLYRWLVANENKMFFRNHTRCAGPEALKGQTLLAAAESH", "length": 353, "header": "tr|F6RMV5-1|F6RMV5_BOVIN Isoform 1 of Leucine rich alpha-2-glycoprotein 1 OS=Bos taurus OX=9913 GN=LRG1 PE=1 SV=1 CANONICAL=F6RMV5-1" }, "locus": { "chromosome": "7", "start_pos": 19598679, "end_pos": 19596356, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000003618.6", "url": "https://www.ensembl.org/id/ENSBTAT00000003618.6" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000003618.4", "url": "https://www.ensembl.org/id/ENSBTAP00000003618.4" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [ { "id": "R-BTA-6798695", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-BTA-6798695", "resource": "Reactome", "description": "Neutrophil degranulation" } ], "orthologs": [ { "uniprot_canonical_ac": "A0A8V1AFE7-1", "protein_name": "Leucine rich alpha-2-glycoprotein 1", "gene_name": "LRG1", "tax_id": 9031, "organism": "Gallus gallus", "sequence": { "sequence": "MALLGHILPPPPPLPLLLLLLPYSHAAPCHPQPNATHFICTEPTLSTFPSGLPPTTVAISVEFTAMTTISPNALAGLPRLQELHLSSNHLAVLPEALLQPVPTLRTLDLTDNLLPDLPAGIFHPSIHLRHLVLQGNLLQALQPSWFVHLTQLHWLNLAGNALLEVPPAALRPLRSLRSLDLAHNHLQHLSADTFVGLQMLERLDLEGNQLRALPPTLFAPTPSLRLLFLQNNTLQVLPDGIFSPLLHLRVLDLAHNHLQALQLPPRSPPGPPLSLDMSGNPWACDCSLLALLQDAAPQLIAARATRCASPAQHRGQEVTAVSQAGDEGCQHGGDKQSPLDH", "length": 341 }, "evidence": [ { "id": "F6RMV5", "url": "https://omabrowser.org/oma/group/F6RMV5/", "database": "OMA" } ], "glygen_name": "Chicken", "common_name": "Chicken" }, { "uniprot_canonical_ac": "M0R8H5-1", "protein_name": "Leucine-rich alpha-2-glycoprotein 1", "gene_name": "Lrg1", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "TLFLLALLGGVSGLRECLILQSVKGSTVSCHGPTEFPSSLPADTVHLSVEFSSLTQLPAAALQGCPGLQELHLSSNRLQELSPGLLAPVPRLRVLDLTRNALRSLPPGLFRSSAALNTLVLRENQLQEASARWLQGLDALGYLDLAENRLRSLPARLLANLGALHTLDLGHNLLESLPEGFLRGPRRLQRLHLEGNRLQRLEAGLLAPQPFLGVLFLNDNQLTAVAADSFRGLKQLDMLDLSNNSLSSTPPGLWAFLGRPTRDMQDGFDVSHNPWVCDKDLVDLCRWLAANRHKMFSQNDTLCAGPEAVRGQRLLDVAELGTL", "length": 323 }, "evidence": [ { "id": "F6RMV5", "url": "https://omabrowser.org/oma/group/F6RMV5/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "P02750-1", "protein_name": "Leucine-rich alpha-2-glycoprotein", "gene_name": "LRG1", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MSSWSRQRPKSPGGIQPHVSRTLFLLLLLAASAWGVTLSPKDCQVFRSDHGSSISCQPPAEIPGYLPADTVHLAVEFFNLTHLPANLLQGASKLQELHLSSNGLESLSPEFLRPVPQLRVLDLTRNALTGLPPGLFQASATLDTLVLKENQLEVLEVSWLHGLKALGHLDLSGNRLRKLPPGLLANFTLLRTLDLGENQLETLPPDLLRGPLQLERLHLEGNKLQVLGKDLLLPQPDLRYLFLNGNKLARVAAGAFQGLRQLDMLDLSNNSLASVPEGLWASLGQPNWDMRDGFDISGNPWICDQNLSDLYRWLQAQKDKMFSQNDTRCAGPEAVKGQTLLAVAKSQ", "length": 347 }, "evidence": [ { "id": "F6RMV5", "url": "https://omabrowser.org/oma/group/F6RMV5/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "Q5RHE5-1", "protein_name": "Leucine-rich alpha-2-glycoprotein precursor", "gene_name": "si:dkey-90m5.4", "tax_id": 7955, "organism": "Danio rerio", "sequence": { "sequence": "MNSWLVRALAVMLVLCSRDALSCPKRCTCHFSAKTTEVVCPDAGLSHFPGDGLPPSTTSLTIQFTNLTVLTSEHLRAVPLLEELHLPGNKLSSLPADILKDLKYLHTIDLTDNELRELPEYVFRHAPLLNLVLKDNRISNIHPDWFPNNSNLTWLDLSGNQLMKFPMAQLQNLRHLKVLHLSQNKIEELPVGCLDAHTALERLYLDQNKIQTLDVKAFSGSTNLTHIFLQKNRIDSLPPTVFQELKRLEYVDLSDNRLQFLSPGILDINTSWVELTFNPWHCDAKIEYLWRKITMESLQSEPKCAAPENLKDRVIATLTRKDMGLKE", "length": 327 }, "evidence": [ { "id": "F6RMV5", "url": "https://omabrowser.org/oma/group/F6RMV5/", "database": "OMA" } ], "glygen_name": "Zebrafish", "common_name": "Zebrafish" } ], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 1, "go_terms": [ { "name": "extracellular space", "id": "GO:0005615", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005615", "evidence": [ { "database": "UniProtKB", "id": "F6RMV5", "url": "https://www.uniprot.org/uniprotkb/F6RMV5" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 4, "go_terms": [ { "name": "positive regulation of angiogenesis", "id": "GO:0045766", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0045766", "evidence": [ { "database": "UniProtKB", "id": "F6RMV5", "url": "https://www.uniprot.org/uniprotkb/F6RMV5" } ], "pmid": "" }, { "name": "positive regulation of transforming growth factor beta receptor signaling pathway", "id": "GO:0030511", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030511", "evidence": [ { "database": "UniProtKB", "id": "F6RMV5", "url": "https://www.uniprot.org/uniprotkb/F6RMV5" } ], "pmid": "" }, { "name": "positive regulation of epithelial to mesenchymal transition", "id": "GO:0010718", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0010718", "evidence": [ { "database": "UniProtKB", "id": "F6RMV5", "url": "https://www.uniprot.org/uniprotkb/F6RMV5" } ], "pmid": "" }, { "name": "wound healing, spreading of epidermal cells", "id": "GO:0035313", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0035313", "evidence": [ { "database": "UniProtKB", "id": "F6RMV5", "url": "https://www.uniprot.org/uniprotkb/F6RMV5" } ], "pmid": "" } ] }, { "name": "Molecular Function", "total": 2, "go_terms": [ { "name": "type II transforming growth factor beta receptor binding", "id": "GO:0005114", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005114", "evidence": [ { "database": "UniProtKB", "id": "F6RMV5", "url": "https://www.uniprot.org/uniprotkb/F6RMV5" } ], "pmid": "" }, { "name": "type I transforming growth factor beta receptor binding", "id": "GO:0034713", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0034713", "evidence": [ { "database": "UniProtKB", "id": "F6RMV5", "url": "https://www.uniprot.org/uniprotkb/F6RMV5" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 192, "end_pos": 194, "annotation": "n_glycosylation_sequon" }, { "start_pos": 331, "end_pos": 333, "annotation": "n_glycosylation_sequon" }, { "start_pos": 56, "end_pos": 58, "annotation": "n_glycosylation_sequon" }, { "start_pos": 85, "end_pos": 87, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "F6RMV5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F6RMV5" }, { "id": "SM00082", "database": "SMART", "url": "http://smart.embl.de/smart/do_annotation.pl?DOMAIN=SM00082" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "LRRCT", "eco_id": "ECO_0000259", "start_pos": 305, "end_pos": 353, "start_aa": "Asn", "end_aa": "His", "glycosite_overlap": [] } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" }, { "name": "homologset.oma", "label": "OMA Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 192, "end_pos": 194 }, { "start_pos": 331, "end_pos": 333 }, { "start_pos": 56, "end_pos": 58 }, { "start_pos": 85, "end_pos": 87 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ], "tool_support": { "graph_view": "yes" } }, { "uniprot_canonical_ac": "G3X7J6-1", "uniprot_ac": "G3X7J6", "uniprot_id": "G3X7J6_BOVIN", "mass": { "chemical_mass": 94073.0, "monoisotopic_mass": 94073.0 }, "refseq": { "ac": "XP_024855462", "name": "exonuclease mut-7 homolog isoform X1", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_024855462" }, "gene_names": [ { "name": "EXD3", "type": "recommended", "evidence": [ { "id": "G3X7J6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3X7J6" } ] }, { "name": "EXD3", "type": "synonym", "evidence": [ { "id": "XP_024855462", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_024855462" } ] } ], "protein_names": [ { "name": "Exonuclease 3'-5' domain containing 3", "type": "synonym", "evidence": [ { "id": "G3X7J6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3X7J6/entry#names_and_taxonomy" } ] }, { "name": "exonuclease mut-7 homolog isoform X1", "type": "synonym", "evidence": [ { "id": "XP_024855462", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_024855462" } ] } ], "function": [], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Bos taurus", "taxid": 9913, "evidence": [ { "database": "UniProtKB", "id": "G3X7J6", "url": "https://www.uniprot.org/uniprotkb/G3X7J6" } ], "common_name": "Bovine", "glygen_name": "Bovine", "reference_species": "Bos taurus [9913]" } ], "gene": [ { "name": "EXD3", "url": "https://www.uniprot.org/uniprotkb/G3X7J6", "locus": { "chromosome": "11", "start_pos": 106330416, "end_pos": 106401276, "strand": "+", "evidence": [ { "database": "Ensembl Gene", "id": "ENSBTAG00000023788", "url": "https://www.ensembl.org/id/ENSBTAG00000023788" } ] } } ], "crossref": [ { "id": "G3X7J6", "url": "https://alphafold.ebi.ac.uk/entry/G3X7J6", "database": "AlphaFoldDB", "categories": [] }, { "id": "ENSBTAG00000023788", "url": "https://bgee.org/?page=gene&gene_id=ENSBTAG00000023788", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "cd06146", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd06146", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "618437", "url": "https://www.ncbi.nlm.nih.gov/gene/618437", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR002562", "url": "https://www.ebi.ac.uk/interpro/entry/IPR002562", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR002782", "url": "https://www.ebi.ac.uk/interpro/entry/IPR002782", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR012337", "url": "https://www.ebi.ac.uk/interpro/entry/IPR012337", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR036397", "url": "https://www.ebi.ac.uk/interpro/entry/IPR036397", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR037432", "url": "https://www.ebi.ac.uk/interpro/entry/IPR037432", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR052408", "url": "https://www.ebi.ac.uk/interpro/entry/IPR052408", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "bta:618437", "url": "https://www.genome.jp/dbget-bin/www_bget?bta:618437", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "PTHR47765", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR47765", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR47765:SF2", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR47765:SF2", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF01612", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF01612", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF01927", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF01927", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "XP_024855462", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_024855462", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0AAA9SZE8", "url": "https://www.uniprot.org/uniprotkb/A0AAA9SZE8", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0AAA9SZE8-1", "url": "https://www.uniprot.org/uniprotkb/A0AAA9SZE8-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "G3X7J6", "url": "https://www.uniprot.org/uniprotkb/G3X7J6", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "G3X7J6-1", "url": "https://www.uniprot.org/uniprotkb/G3X7J6-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MDPGDPEEKPAAGDPAGGQDPRLFPQTLQTLWSTRELRQLREEAWKWFAALDNPLTTLLDMLDASRGCGGRDPSLEAWVARELERWLQAQPHPGPAQGGRALKPLQARAVRLLTEGPPSLVEPLVSIFQLQDADRSPVLAHIHRLHQEGKFKEAIVLGTKLQLQADLDVEKMCVPLLLQDKVGLAEHYVDSLPHLQQRLLALMDSWCQPGFDIRVVARQYPQATLRLERLSPRALGRHVLRLLEQYSLDPALCPNAVTQQRLAALRYLCYKRLVERSMSQESWAELVQGLVGQDECLQEQLLQLLASLEDVAMVAQCALDLSLPVERLPATVVAEMSQLRLQERTAKAPSEDRRDDCYQLPISRDDIYFLASWEELARHEDTLLQPGQVVGVDLEWRPSFGTGGRPRVSLMQVAVEGRVFLLDLPRLSSPAGGQGPRAFSQLVSQLLSDPSITKLGYGMAGDLRSLGTSYPALAQAGQKLQGGLDLLQVHRQMRVADRPAPAVDGAAGPRGLSLLVQQVLGKPLDKTQQLSNWDRRPLGEGQLVYAAADAYCLLEVYWALCREPARFHLPGALPWSLRLGRSERHGTWEPPLQQASASPWQVLSPEDAAPEVPARAFRVVCDSMLGGLGRTLRCLGVDVRVLHSGEDHRQAAEVARQEGRVILTSGLPYHKLRAQVGAGRCLAVDCSLKAQQQAKAILRHFNVRVTPADIFSRCQACNCDQYLKVSKDMMKQLVRLSVHLGGPGGASTESSHSDGEQETDSAPEEAPGHCSYDPPCRWLEDADLQTHVPATLANGTRLQLAGVPAGVLRRPGLRHFYCCPGCGKVFWEGTHLARVTSNFQEILEGAPRPASGPS", "length": 854, "header": "tr|G3X7J6-1|G3X7J6_BOVIN Isoform 1 of Exonuclease 3'-5' domain containing 3 OS=Bos taurus OX=9913 GN=EXD3 PE=4 SV=3 CANONICAL=G3X7J6-1" }, "isoforms": [ { "isoform_ac": "A0AAA9SZE8-1", "url": "https://www.uniprot.org/uniprotkb/A0AAA9SZE8/entry", "sequence": { "sequence": "MDPGDPEEKPAAGDPAGGQDPRLFPQTLQTLWSTRELRQLREEAWKWFAALDNPLTTLLDMLDASRGCGGRDPSLEAWVARELERWLQAQPHPGPAQAIVLGTKLQLQADLDVEKMCVPLLLQDKVGLAEHYVDSLPHLQQRLLALMDSWCQPGFDIRVVARQYPQATLRLERLSPRALGRHVLRLLEQYSLDPALCPNAVTQQRLAALRYLCYKRLVERSMSQESWAELVQGLVGQDECLQEQLLQLLASLEDVAMVAQCALDLSLPVERLPATVVAEMSQLRLQERTAKAPSEDRRDDCYQLPISRDDIYFLASWEELARHEDTLLQPGQVVGVDLEWRPSFGTGGRPRVSLMQVAVEGRVFLLDLPRLSSPAGGQGPRAFSQLVSQLLSDPSITKLGYGMAGDLRSLGTSYPALAQAGQKLQGGLDLLQVHRQMRVADRPAPAVDGAAGPRGLSLLVQQVLGKPLDKTQQLSNWDRRPLGEGQLVYAAADAYCLLEVYWALCREPARFHLPGALPWSLRLGRSERHGTWEPPLQQASASPWQVLSPEDAAPEVPARAFRVVCDSMLGGLGRTLRCLGVDVRVLHSGEDHRQAAEVARQEGRVILTSGLPYHKLRAQVGAGRCLAVDCSLKAQQQAKAILRHFNVRVTPADIFSRCQACNCDQYLKVSKDMMKQLVRLSVHLGGPGGASTESSHSDGEQETDSAPEEAPGHCSYDPPCRWLEDADLQTHVPATLANGTRLQLAGVPAGVLRRPGLRHFYCCPGCGKVFWEGTHLARVTSNFQEILEGAPRPASGPS", "length": 798, "header": "tr|A0AAA9SZE8-1|G3X7J6_BOVIN Computationally mapped isoform of Exonuclease 3'-5' domain containing 3 OS=Bos taurus OX=9913 GN=EXD3 PE=4 SV=1 CANONICAL=G3X7J6-1" }, "locus": { "chromosome": "11", "start_pos": 106387884, "end_pos": 106331420, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000124749.1", "url": "https://www.ensembl.org/id/ENSBTAT00000124749.1" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000088744.1", "url": "https://www.ensembl.org/id/ENSBTAP00000088744.1" } ] } }, { "isoform_ac": "G3X7J6-1", "url": "https://www.uniprot.org/uniprotkb/G3X7J6/entry", "sequence": { "sequence": "MDPGDPEEKPAAGDPAGGQDPRLFPQTLQTLWSTRELRQLREEAWKWFAALDNPLTTLLDMLDASRGCGGRDPSLEAWVARELERWLQAQPHPGPAQGGRALKPLQARAVRLLTEGPPSLVEPLVSIFQLQDADRSPVLAHIHRLHQEGKFKEAIVLGTKLQLQADLDVEKMCVPLLLQDKVGLAEHYVDSLPHLQQRLLALMDSWCQPGFDIRVVARQYPQATLRLERLSPRALGRHVLRLLEQYSLDPALCPNAVTQQRLAALRYLCYKRLVERSMSQESWAELVQGLVGQDECLQEQLLQLLASLEDVAMVAQCALDLSLPVERLPATVVAEMSQLRLQERTAKAPSEDRRDDCYQLPISRDDIYFLASWEELARHEDTLLQPGQVVGVDLEWRPSFGTGGRPRVSLMQVAVEGRVFLLDLPRLSSPAGGQGPRAFSQLVSQLLSDPSITKLGYGMAGDLRSLGTSYPALAQAGQKLQGGLDLLQVHRQMRVADRPAPAVDGAAGPRGLSLLVQQVLGKPLDKTQQLSNWDRRPLGEGQLVYAAADAYCLLEVYWALCREPARFHLPGALPWSLRLGRSERHGTWEPPLQQASASPWQVLSPEDAAPEVPARAFRVVCDSMLGGLGRTLRCLGVDVRVLHSGEDHRQAAEVARQEGRVILTSGLPYHKLRAQVGAGRCLAVDCSLKAQQQAKAILRHFNVRVTPADIFSRCQACNCDQYLKVSKDMMKQLVRLSVHLGGPGGASTESSHSDGEQETDSAPEEAPGHCSYDPPCRWLEDADLQTHVPATLANGTRLQLAGVPAGVLRRPGLRHFYCCPGCGKVFWEGTHLARVTSNFQEILEGAPRPASGPS", "length": 854, "header": "tr|G3X7J6-1|G3X7J6_BOVIN Isoform 1 of Exonuclease 3'-5' domain containing 3 OS=Bos taurus OX=9913 GN=EXD3 PE=4 SV=3 CANONICAL=G3X7J6-1" }, "locus": { "chromosome": "11", "start_pos": 106387884, "end_pos": 106331420, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000032625.6", "url": "https://www.ensembl.org/id/ENSBTAT00000032625.6" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000032554.6", "url": "https://www.ensembl.org/id/ENSBTAP00000032554.6" } ] } } ], "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "other", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 706, "start_aa": "Thr", "end_pos": 706, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr706", "evidence": [ { "id": "", "database": "GlyGen", "url": "https://data.glygen.org/" } ], "filter_code": "000000000000000010000.00000000001000.0.01000" } ], "phosphorylation": [], "glycation": [], "keywords": [ "glycoprotein", "glycoprotein_predicted" ], "publication": [], "pathway": [ { "id": "bta:618437", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?bta:618437", "resource": "KEGG Pathway" } ], "orthologs": [], "go_annotation": { "categories": [ { "name": "Molecular Function", "total": 2, "go_terms": [ { "name": "nucleic acid binding", "id": "GO:0003676", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003676", "evidence": [ { "database": "UniProtKB", "id": "G3X7J6", "url": "https://www.uniprot.org/uniprotkb/G3X7J6" } ], "pmid": "" }, { "name": "3'-5' exonuclease activity", "id": "GO:0008408", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008408", "evidence": [ { "database": "UniProtKB", "id": "G3X7J6", "url": "https://www.uniprot.org/uniprotkb/G3X7J6" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 1, "go_terms": [ { "name": "nucleobase-containing compound metabolic process", "id": "GO:0006139", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006139", "evidence": [ { "database": "UniProtKB", "id": "G3X7J6", "url": "https://www.uniprot.org/uniprotkb/G3X7J6" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 794, "end_pos": 796, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [ { "pdb_id": "AF-G3X7J6-F1", "pdb_chain": "global", "start_pos": 1, "end_pos": 854, "overlap": "1.0", "method": "AlphaFold", "type": "alphafold", "resolution": -1.0, "url": "https://data.glygen.org/ln2downloads/pdb/current/AF-G3X7J6-F1.pdb", "url_external": "https://alphafold.ebi.ac.uk/entry/G3X7J6" } ], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "G3X7J6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3X7J6" }, { "id": "SM00474", "database": "SMART", "url": "http://smart.embl.de/smart/do_annotation.pl?DOMAIN=SM00474" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "3'-5' exonuclease", "eco_id": "ECO_0000259", "start_pos": 367, "end_pos": 565, "start_aa": "Ile", "end_aa": "Ala", "glycosite_overlap": [] } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [ 706 ], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 794, "end_pos": 796 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 1 }, { "field": "total_sites", "count": 1 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 1 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "exact_sites", "count": 1 }, { "field": "exact_o_linked_sites", "count": 1 }, { "field": "fuzzy_sites", "count": 0 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_pos", "start_aa", "end_pos", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 1 }, { "field": "total_sites", "count": 1 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 1 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "exact_sites", "count": 1 }, { "field": "exact_o_linked_sites", "count": 1 }, { "field": "fuzzy_sites", "count": 0 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_pos", "start_aa", "end_pos", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ], "tool_support": { "graph_view": "yes" } }, { "uniprot_canonical_ac": "F6RNL0-1", "uniprot_ac": "F6RNL0", "uniprot_id": "F6RNL0_BOVIN", "mass": { "chemical_mass": 103299.0, "monoisotopic_mass": 103299.0 }, "refseq": { "ac": "XP_005208306", "name": "nucleolar protein 14 isoform X1", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_005208306" }, "gene_names": [ { "name": "NOP14", "type": "recommended", "evidence": [ { "id": "F6RNL0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F6RNL0" } ] }, { "name": "NOL14", "type": "synonym", "evidence": [ { "id": "XP_005208306", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_005208306" } ] }, { "name": "NOP14", "type": "synonym", "evidence": [ { "id": "XP_005208306", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_005208306" } ] } ], "protein_names": [ { "name": "NOP14 nucleolar protein", "type": "synonym", "evidence": [ { "id": "F6RNL0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F6RNL0/entry#names_and_taxonomy" } ] }, { "name": "nucleolar protein 14 isoform X1", "type": "synonym", "evidence": [ { "id": "XP_005208306", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_005208306" } ] } ], "function": [ { "annotation": "Involved in nucleolar processing of pre-18S ribosomal RNA. Has a role in the nuclear export of 40S pre-ribosomal subunit to the cytoplasm.", "evidence": [ { "database": "UniProtKB", "id": "A0AAA9T1D5", "url": "https://www.uniprot.org/uniprotkb/A0AAA9T1D5#function" }, { "database": "UniProtKB", "id": "ARBA00024695", "url": "https://www.uniprot.org/uniprotkb/ARBA00024695#function" }, { "database": "UniProtKB", "id": "F6RNL0", "url": "https://www.uniprot.org/uniprotkb/F6RNL0#function" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Bos taurus", "taxid": 9913, "evidence": [ { "database": "UniProtKB", "id": "F6RNL0", "url": "https://www.uniprot.org/uniprotkb/F6RNL0" } ], "common_name": "Bovine", "glygen_name": "Bovine", "reference_species": "Bos taurus [9913]" } ], "gene": [ { "name": "NOP14", "url": "https://www.uniprot.org/uniprotkb/F6RNL0", "locus": { "chromosome": "6", "start_pos": 115805584, "end_pos": 115790549, "strand": "-", "evidence": [ { "database": "Ensembl Gene", "id": "ENSBTAG00000001504", "url": "https://www.ensembl.org/id/ENSBTAG00000001504" } ] } } ], "crossref": [ { "id": "F6RNL0", "url": "https://alphafold.ebi.ac.uk/entry/F6RNL0", "database": "AlphaFoldDB", "categories": [] }, { "id": "516995", "url": "https://www.ncbi.nlm.nih.gov/gene/516995", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR007276", "url": "https://www.ebi.ac.uk/interpro/entry/IPR007276", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "PTHR23183", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR23183", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR23183:SF0", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR23183:SF0", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF04147", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF04147", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "XP_005208306", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_005208306", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0AAA9T1D5", "url": "https://www.uniprot.org/uniprotkb/A0AAA9T1D5", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0AAA9T1D5-1", "url": "https://www.uniprot.org/uniprotkb/A0AAA9T1D5-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "F6RNL0", "url": "https://www.uniprot.org/uniprotkb/F6RNL0", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "F6RNL0-1", "url": "https://www.uniprot.org/uniprotkb/F6RNL0-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MGKARSAARGKASAAPAGALGGRARPNPNPFEVKVNRQKFQVLGRKTRHDVGLPGVSRARALQKRTQTLLKEYKERDKSNVFRDKRFGEYNSSISPEEKMMKRFALEQQRQHEKKSIYNLNEDEELTHYGQSLADIEKHNDIVDSDSDTEGRGALSAELTATHFGGGSGPVPGKAAQQPSGGEEPPKSRRELIEELIARSKQEKRERQAQREDALELTEKLDQDWKEIQALLACKTPKSESGGGKEKPKPDAYDMMVRELGFEMKAQPSNRMKTEEELAREEQERLRRLEAERLRRMLGRDEDAHSKRPKHLSADDLNDGFVLDTDDRRLLSYKDGKMNVEEEPSGDSSGGDSGEEEEEKGEGWSEGGPEDSDSPDGHSDLESDADSEDARSADGLVGRESDGVEVRAQLQGDQRPSPGERLPRDDRAAARAQLPYTFAVPESCEELKSLLSGKSMEDQLLVVERIQKCNHPSLAVGNKAKLEVRWLSPCGTRSGQRPGSHGTDGHRALAVFAAGYFPWGRASKRGLDGCRLRKLFGFLLEYIGDLAVSDPPDLGVIDKLVVPLYDLCQMFPESASDAVKFVLRDAMHEMEGTVETTGRAAFPGLDVLIYLKIAGMLFPTSDFWHPVITPALLCLSQLLTKCPVRSLQDAVKGLFVCCVFLDYVALSQRFIPELINFLAGILHMATPNKQSQGYTLVHPFRALGKNSELLLVSDEEDMATWQRRSLPLQWAGGLKAQTETEANHTRLSCLALCLALVRRCVLAYGTLPSFHDIARPLRALLTEHLATRCCPPTLQELSRSVLTEMENQPRHYRPLVCEKSKPVPLKLFTPRLVKVLEFGRKQGSTREEQERRRLIHKHKREFKGAVREIRKDNQFLARMRLSEIMERDAERKRKVKQLFNSLATQEGEWKALKRKKFKK", "length": 919, "header": "tr|F6RNL0-1|F6RNL0_BOVIN Isoform 1 of NOP14 nucleolar protein OS=Bos taurus OX=9913 GN=NOP14 PE=3 SV=1 CANONICAL=F6RNL0-1" }, "isoforms": [ { "isoform_ac": "A0AAA9T1D5-1", "url": "https://www.uniprot.org/uniprotkb/A0AAA9T1D5/entry", "sequence": { "sequence": "MTVLCKRTQTLLKEYKERDKSNVFRDKRFGEYNSSISPEEKMMKRFALEQQRQHEKKSIYNLNEDEELTHYGQSLADIEKHNDIVDSDSDTEGRGALSAELTATHFGGGSGPVPGKAAQQPSGGEEPPKSRRELIEELIARSKQEKRERQAQREDALELTEKLDQDWKEIQALLACKTPKSESGGGKEKPKPDAYDMMVRELGFEMKAQPSNRMKTEEELAREEQERLRRLEAERLRRMLGRDEDAHSKRPKHLSADDLNDGFVLDTDDRRLLSYKDGKMNVEEEPSGDSSGGDSGEEEEEKGEGWSEGGPEDSDSPDGHSDLESDADSEDARSADGLVGRESDGVEVRAQLQGDQRPSPGERLPRDDRAAARAQLPYTFAVPESCEELKSLLSGKSMEDQLLVVERIQKCNHPSLAVGNKAKLEKLFGFLLEYIGDLAVSDPPDLGVIDKLVVPLYDLCQMFPESASDAVKFVLRDAMHEMEGTVETTGRAAFPGLDVLIYLKIAGMLFPTSDFWHPVITPALLCLSQLLTKCPVRSLQDAVKGLFVCCVFLDYVALSQRFIPELINFLAGILHMATPNKQSQGYTLVHPFRALGKNSELLLVSDEEDMATWQRRSLPLQWAGGLKAQTETEANHTRLSCLALCLALVRRCVLAYGTLPSFHDIARPLRALLTEHLATRCCPPTLQELSRSVLTEMENQPRHYRPLVCEKSKPVPLKLFTPRLVKVLEFGRKQGSTREEQERRRLIHKHKREFKGAVREIRKDNQFLARMRLSEIMERDAERKRKVKQLFNSLATQEGEWKALKRKKFKK", "length": 811, "header": "tr|A0AAA9T1D5-1|F6RNL0_BOVIN Computationally mapped isoform of NOP14 nucleolar protein OS=Bos taurus OX=9913 GN=NOP14 PE=3 SV=1 CANONICAL=F6RNL0-1" }, "locus": { "chromosome": "6", "start_pos": 115805220, "end_pos": 115791555, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000133432.2", "url": "https://www.ensembl.org/id/ENSBTAT00000133432.2" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000089461.1", "url": "https://www.ensembl.org/id/ENSBTAP00000089461.1" } ] } }, { "isoform_ac": "F6RNL0-1", "url": "https://www.uniprot.org/uniprotkb/F6RNL0/entry", "sequence": { "sequence": "MGKARSAARGKASAAPAGALGGRARPNPNPFEVKVNRQKFQVLGRKTRHDVGLPGVSRARALQKRTQTLLKEYKERDKSNVFRDKRFGEYNSSISPEEKMMKRFALEQQRQHEKKSIYNLNEDEELTHYGQSLADIEKHNDIVDSDSDTEGRGALSAELTATHFGGGSGPVPGKAAQQPSGGEEPPKSRRELIEELIARSKQEKRERQAQREDALELTEKLDQDWKEIQALLACKTPKSESGGGKEKPKPDAYDMMVRELGFEMKAQPSNRMKTEEELAREEQERLRRLEAERLRRMLGRDEDAHSKRPKHLSADDLNDGFVLDTDDRRLLSYKDGKMNVEEEPSGDSSGGDSGEEEEEKGEGWSEGGPEDSDSPDGHSDLESDADSEDARSADGLVGRESDGVEVRAQLQGDQRPSPGERLPRDDRAAARAQLPYTFAVPESCEELKSLLSGKSMEDQLLVVERIQKCNHPSLAVGNKAKLEVRWLSPCGTRSGQRPGSHGTDGHRALAVFAAGYFPWGRASKRGLDGCRLRKLFGFLLEYIGDLAVSDPPDLGVIDKLVVPLYDLCQMFPESASDAVKFVLRDAMHEMEGTVETTGRAAFPGLDVLIYLKIAGMLFPTSDFWHPVITPALLCLSQLLTKCPVRSLQDAVKGLFVCCVFLDYVALSQRFIPELINFLAGILHMATPNKQSQGYTLVHPFRALGKNSELLLVSDEEDMATWQRRSLPLQWAGGLKAQTETEANHTRLSCLALCLALVRRCVLAYGTLPSFHDIARPLRALLTEHLATRCCPPTLQELSRSVLTEMENQPRHYRPLVCEKSKPVPLKLFTPRLVKVLEFGRKQGSTREEQERRRLIHKHKREFKGAVREIRKDNQFLARMRLSEIMERDAERKRKVKQLFNSLATQEGEWKALKRKKFKK", "length": 919, "header": "tr|F6RNL0-1|F6RNL0_BOVIN Isoform 1 of NOP14 nucleolar protein OS=Bos taurus OX=9913 GN=NOP14 PE=3 SV=1 CANONICAL=F6RNL0-1" }, "locus": { "chromosome": "6", "start_pos": 115805220, "end_pos": 115790626, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000044320.5", "url": "https://www.ensembl.org/id/ENSBTAT00000044320.5" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000041827.3", "url": "https://www.ensembl.org/id/ENSBTAP00000041827.3" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [], "orthologs": [], "go_annotation": { "categories": [ { "name": "Biological Process", "total": 1, "go_terms": [ { "name": "rRNA processing", "id": "GO:0006364", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006364", "evidence": [ { "database": "UniProtKB", "id": "F6RNL0", "url": "https://www.uniprot.org/uniprotkb/F6RNL0" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 2, "go_terms": [ { "name": "small-subunit processome", "id": "GO:0032040", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0032040", "evidence": [ { "database": "UniProtKB", "id": "F6RNL0", "url": "https://www.uniprot.org/uniprotkb/F6RNL0" } ], "pmid": "" }, { "name": "nucleoplasm", "id": "GO:0005654", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005654", "evidence": [ { "database": "UniProtKB", "id": "F6RNL0", "url": "https://www.uniprot.org/uniprotkb/F6RNL0" } ], "pmid": "" } ] }, { "name": "Molecular Function", "total": 1, "go_terms": [ { "name": "enzyme binding", "id": "GO:0019899", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0019899", "evidence": [ { "database": "UniProtKB", "id": "F6RNL0", "url": "https://www.uniprot.org/uniprotkb/F6RNL0" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 743, "end_pos": 745, "annotation": "n_glycosylation_sequon" }, { "start_pos": 91, "end_pos": 93, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 743, "end_pos": 745 }, { "start_pos": 91, "end_pos": 93 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ], "tool_support": { "graph_view": "yes" } }, { "uniprot_canonical_ac": "F6RWN3-1", "uniprot_ac": "F6RWN3", "uniprot_id": "F6RWN3_BOVIN", "mass": { "chemical_mass": 36470.0, "monoisotopic_mass": 36470.0 }, "refseq": {}, "gene_names": [ { "name": "CD200", "type": "recommended", "evidence": [ { "id": "F6RWN3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F6RWN3" } ] } ], "protein_names": [ { "name": "CD200 molecule", "type": "synonym", "evidence": [ { "id": "F6RWN3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F6RWN3/entry#names_and_taxonomy" } ] } ], "function": [], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Bos taurus", "taxid": 9913, "evidence": [ { "database": "UniProtKB", "id": "F6RWN3", "url": "https://www.uniprot.org/uniprotkb/F6RWN3" } ], "common_name": "Bovine", "glygen_name": "Bovine", "reference_species": "Bos taurus [9913]" } ], "gene": [ { "name": "CD200", "url": "https://www.uniprot.org/uniprotkb/F6RWN3", "locus": { "chromosome": "1", "start_pos": 57206343, "end_pos": 57075174, "strand": "-", "evidence": [ { "database": "Ensembl Gene", "id": "ENSBTAG00000033319", "url": "https://www.ensembl.org/id/ENSBTAG00000033319" } ] } } ], "crossref": [ { "id": "F6RWN3", "url": "https://alphafold.ebi.ac.uk/entry/F6RWN3", "database": "AlphaFoldDB", "categories": [] }, { "id": "cd05846", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd05846", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "IPR007110", "url": "https://www.ebi.ac.uk/interpro/entry/IPR007110", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR013106", "url": "https://www.ebi.ac.uk/interpro/entry/IPR013106", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR013151", "url": "https://www.ebi.ac.uk/interpro/entry/IPR013151", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR013783", "url": "https://www.ebi.ac.uk/interpro/entry/IPR013783", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR033321", "url": "https://www.ebi.ac.uk/interpro/entry/IPR033321", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR036179", "url": "https://www.ebi.ac.uk/interpro/entry/IPR036179", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR047164", "url": "https://www.ebi.ac.uk/interpro/entry/IPR047164", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "PTHR46841", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR46841", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR46841:SF3", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR46841:SF3", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00047", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00047", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF07686", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF07686", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "A0AAA9T851", "url": "https://www.uniprot.org/uniprotkb/A0AAA9T851", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0AAA9T851-1", "url": "https://www.uniprot.org/uniprotkb/A0AAA9T851-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0AAA9T881", "url": "https://www.uniprot.org/uniprotkb/A0AAA9T881", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0AAA9T881-1", "url": "https://www.uniprot.org/uniprotkb/A0AAA9T881-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0AAA9TIX5", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TIX5", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0AAA9TIX5-1", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TIX5-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "F6RWN3", "url": "https://www.uniprot.org/uniprotkb/F6RWN3", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "F6RWN3-1", "url": "https://www.uniprot.org/uniprotkb/F6RWN3-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MQCLVFRRLVCHLSTFQLIWFLAPLILCRAQVVTQDVRGLLNTPASLRCSLKNPQEVLIVTWQKIKAVSPENMITYSENHGVVVQPAYKDKINITQLGLMNSTITFWNTTLEDEACYKCLFNTFGSGKISGIACLTLFVQPTVFLHYKLSEDHLNITCSANARPAPMISWKVFGSGIENSTEIVSHPNGTTSVTSILQIKDPKTQVGKDVICQVLHLGTVTDYRETVNKGFWFSVPLLLSIVSLVILLVLISILLYWKRHRNQDRGRFVSMARGSQCCSCLENRLGISGRCRNYAIISLKLIHLMLSTLVEEQTFLQAFFFIF", "length": 323, "header": "tr|F6RWN3-1|F6RWN3_BOVIN Isoform 1 of CD200 molecule OS=Bos taurus OX=9913 GN=CD200 PE=4 SV=2 CANONICAL=F6RWN3-1" }, "isoforms": [ { "isoform_ac": "A0AAA9T851-1", "url": "https://www.uniprot.org/uniprotkb/A0AAA9T851/entry", "sequence": { "sequence": "MITYSENHGVVVQPAYKDKINITQLGLMNSTITFWNTTLEDEACYKCLFNTFGSGKISGIACLTLFVQPTVFLHYKLSEDHLNITCSANARPAPMISWKVFGSGIENSTEIVSHPNGTTSVTSILQIKDPKTQVGKDVICQVLHLGTVTDYRETVNKGFWFSVPLLLSIVSLVILLVLISILLYWKRHRNQDREP", "length": 195, "header": "tr|A0AAA9T851-1|F6RWN3_BOVIN Computationally mapped isoform of CD200 molecule OS=Bos taurus OX=9913 GN=CD200 PE=4 SV=2 CANONICAL=F6RWN3-1" }, "locus": { "chromosome": "1", "start_pos": 57147883, "end_pos": 57134092, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000113090.2", "url": "https://www.ensembl.org/id/ENSBTAT00000113090.2" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000094910.2", "url": "https://www.ensembl.org/id/ENSBTAP00000094910.2" } ] } }, { "isoform_ac": "A0AAA9T881-1", "url": "https://www.uniprot.org/uniprotkb/A0AAA9T881/entry", "sequence": { "sequence": "MQCLVFRRLVCHLSTFQLIWFLAPLILCRAQVVTQDVRGLLNTPASLRCSLKNPQEVLIVTWQKIKAVSPENMITYSENHGVVVQPAYKDKINITQLGLMNSTITFWNTTLEDEACYKCLFNTFGSGKISGIACLTLFVQPTVFLHYKLSEDHLNITCSANARPAPMISWKVFGSGIENSTEIVSHPNGTTSVTSILQIKDPKTQVGKDVICQVLHLGTVTDYRETVNKGFWFSVPLLLSIVSLVILLVLISILLYWKRHRNQDRGHLPNPGIEPGSPALQADSLPSEPPGKS", "length": 293, "header": "tr|A0AAA9T881-1|F6RWN3_BOVIN Computationally mapped isoform of CD200 molecule OS=Bos taurus OX=9913 GN=CD200 PE=4 SV=2 CANONICAL=F6RWN3-1" }, "locus": { "chromosome": "1", "start_pos": 57142392, "end_pos": 57126676, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000103280.2", "url": "https://www.ensembl.org/id/ENSBTAT00000103280.2" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000093018.2", "url": "https://www.ensembl.org/id/ENSBTAP00000093018.2" } ] } }, { "isoform_ac": "A0AAA9TIX5-1", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TIX5/entry", "sequence": { "sequence": "MQCLVFRRLVCHLSTFQLIWFLAPLILCRAQVVTQDVRGLLNTPASLRCSLKNPQEVLIVTWQKIKAVSPENMITYSENHGVVVQPAYKDKINITQLGLMNSTITFWNTTLEDEACYKCLFNTFGSGKISGIACLTLFVQPTVFLHYKLSEDHLNITCSANARPAPMISWKVFGSGIENSTEIVSHPNGTTSVTSILQIKDPKTQVGKDVICQVLHLGTVTDYRETVNKGFWFSVPLLLSIVSLVILLVLISILLYWKRHRNQDRGWRQEEI", "length": 272, "header": "tr|A0AAA9TIX5-1|F6RWN3_BOVIN Computationally mapped isoform of CD200 molecule OS=Bos taurus OX=9913 GN=CD200 PE=4 SV=1 CANONICAL=F6RWN3-1" }, "locus": { "chromosome": "1", "start_pos": 57206117, "end_pos": 57126676, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000117547.2", "url": "https://www.ensembl.org/id/ENSBTAT00000117547.2" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000097107.1", "url": "https://www.ensembl.org/id/ENSBTAP00000097107.1" } ] } }, { "isoform_ac": "F6RWN3-1", "url": "https://www.uniprot.org/uniprotkb/F6RWN3/entry", "sequence": { "sequence": "MQCLVFRRLVCHLSTFQLIWFLAPLILCRAQVVTQDVRGLLNTPASLRCSLKNPQEVLIVTWQKIKAVSPENMITYSENHGVVVQPAYKDKINITQLGLMNSTITFWNTTLEDEACYKCLFNTFGSGKISGIACLTLFVQPTVFLHYKLSEDHLNITCSANARPAPMISWKVFGSGIENSTEIVSHPNGTTSVTSILQIKDPKTQVGKDVICQVLHLGTVTDYRETVNKGFWFSVPLLLSIVSLVILLVLISILLYWKRHRNQDRGRFVSMARGSQCCSCLENRLGISGRCRNYAIISLKLIHLMLSTLVEEQTFLQAFFFIF", "length": 323, "header": "tr|F6RWN3-1|F6RWN3_BOVIN Isoform 1 of CD200 molecule OS=Bos taurus OX=9913 GN=CD200 PE=4 SV=2 CANONICAL=F6RWN3-1" }, "locus": { "chromosome": "1", "start_pos": 57158490, "end_pos": 57126676, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000027169.6", "url": "https://www.ensembl.org/id/ENSBTAT00000027169.6" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000027169.5", "url": "https://www.ensembl.org/id/ENSBTAP00000027169.5" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [], "orthologs": [], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 4, "go_terms": [ { "name": "membrane", "id": "GO:0016020", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016020", "evidence": [ { "database": "UniProtKB", "id": "F6RWN3", "url": "https://www.uniprot.org/uniprotkb/F6RWN3" } ], "pmid": "" }, { "name": "cell surface", "id": "GO:0009986", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0009986", "evidence": [ { "database": "UniProtKB", "id": "F6RWN3", "url": "https://www.uniprot.org/uniprotkb/F6RWN3" } ], "pmid": "" }, { "name": "axon", "id": "GO:0030424", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030424", "evidence": [ { "database": "UniProtKB", "id": 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], "glygen_name": "Mouse", "common_name": "Mouse" } ], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 1, "go_terms": [ { "name": "plasma membrane", "id": "GO:0005886", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005886", "evidence": [ { "database": "UniProtKB", "id": "G3MY26", "url": "https://www.uniprot.org/uniprotkb/G3MY26" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 2, "go_terms": [ { "name": "homophilic cell adhesion via plasma membrane adhesion molecules", "id": "GO:0007156", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007156", "evidence": [ { "database": "UniProtKB", "id": "G3MY26", "url": "https://www.uniprot.org/uniprotkb/G3MY26" } ], "pmid": "" }, { "name": "heterophilic cell-cell adhesion via plasma membrane cell adhesion molecules", "id": "GO:0007157", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007157", "evidence": [ { "database": "UniProtKB", "id": "G3MY26", "url": "https://www.uniprot.org/uniprotkb/G3MY26" } ], 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"length": 1365, "header": "tr|G3N1L4-1|G3N1L4_BOVIN Isoform 1 of Microtubule associated scaffold protein 2 OS=Bos taurus OX=9913 GN=MTUS2 PE=4 SV=3 CANONICAL=G3N1L4-1" }, "locus": { "chromosome": "12", "start_pos": 31271454, "end_pos": 31002538, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000063280.4", "url": "https://www.ensembl.org/id/ENSBTAT00000063280.4" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000055762.3", "url": "https://www.ensembl.org/id/ENSBTAP00000055762.3" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [], "orthologs": [], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 4, "go_terms": [ { "name": "nucleus", "id": "GO:0005634", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005634", "evidence": [ { "database": "UniProtKB", "id": "G3N1L4", "url": "https://www.uniprot.org/uniprotkb/G3N1L4" } ], "pmid": "" }, { "name": "centrosome", 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}, { "start_pos": 443, "end_pos": 445 }, { "start_pos": 877, "end_pos": 879 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": 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"total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ], "tool_support": { "graph_view": "yes" } }, { "uniprot_canonical_ac": "G3X6M2-1", "uniprot_ac": "G3X6M2", "uniprot_id": "G3X6M2_BOVIN", "mass": { "chemical_mass": 58710.0, "monoisotopic_mass": 58710.0 }, "refseq": { "ac": "XP_005216732", "name": "complement decay-accelerating factor isoform X9", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_005216732" }, "gene_names": [ { "name": "CD55", "type": "recommended", "evidence": [ { "id": "G3X6M2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3X6M2" } ] }, { "name": "CD55", "type": "synonym", "evidence": [ { "id": "XP_005216732", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_005216732" } ] }, { "name": "DAF", "type": "synonym", "evidence": [ { "id": "XP_005216732", "database": "RefSeq", "url": 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Interaction of daf with cell-associated C4b and C3b polypeptides interferes with their ability to catalyze the conversion of C2 and factor B to enzymatically active C2a and Bb and thereby prevents the formation of C4b2a and C3bBb, the amplification convertases of the complement cascade. Inhibits complement activation by destabilizing and preventing the formation of C3 and C5 convertases, which prevents complement damage.", "evidence": [ { "database": "UniProtKB", "id": "G3X6M2", "url": "https://www.uniprot.org/uniprotkb/G3X6M2#function" }, { "database": "UniProtKB", "id": "ARBA00045541", "url": "https://www.uniprot.org/uniprotkb/ARBA00045541#function" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Bos taurus", "taxid": 9913, "evidence": [ { "database": "UniProtKB", "id": "G3X6M2", "url": "https://www.uniprot.org/uniprotkb/G3X6M2" } ], "common_name": "Bovine", "glygen_name": "Bovine", "reference_species": "Bos taurus [9913]" } ], "gene": [ { "name": "CD55", "url": "https://www.uniprot.org/uniprotkb/G3X6M2", "locus": { "chromosome": "16", "start_pos": 5279267, "end_pos": 5251806, "strand": "-", "evidence": [ { "database": "Ensembl Gene", "id": "ENSBTAG00000006984", "url": "https://www.ensembl.org/id/ENSBTAG00000006984" } ] } } ], "crossref": [ { "id": "G3X6M2", "url": "https://alphafold.ebi.ac.uk/entry/G3X6M2", "database": "AlphaFoldDB", "categories": [] }, { "id": "ENSBTAG00000006984", "url": "https://bgee.org/?page=gene&gene_id=ENSBTAG00000006984", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "cd00033", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd00033", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "518609", "url": "https://www.ncbi.nlm.nih.gov/gene/518609", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR000436", "url": "https://www.ebi.ac.uk/interpro/entry/IPR000436", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR035976", "url": "https://www.ebi.ac.uk/interpro/entry/IPR035976", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR050350", "url": "https://www.ebi.ac.uk/interpro/entry/IPR050350", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "G3X6M2", "url": "https://www.orthodb.org/?gene=G3X6M2", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR19325", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR19325", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR19325:SF317", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR19325:SF317", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00084", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00084", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "XP_005216732", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_005216732", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "G3X6M2", "url": "https://www.uniprot.org/uniprotkb/G3X6M2", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "G3X6M2-1", "url": "https://www.uniprot.org/uniprotkb/G3X6M2-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MGLPPLLRPAPGVRKALAHSSRSQSFGDCSLPPDVPNAQAALGGLTSFPEKRTVTYKCNRGFVKVPGKADSVICENNKWSELAVFCNRSCDVPTRLLFASLKKSYSQQNYFPEGTTVEYECRQGYIRDPSLSGNITCLQNFVWSKPDRFCKKKSCPKPREIENGHVNITTDILLGATIYFSCNAGYKLVGATFSFCAPVGNTVGWTNEFPECQEILCPEPPKVDHGMIQEKQNSYAYGQSVTYKCMEGFTLHGESSIYCTVKDDQGEWSGPLPQCRETDVTPTVPKSTEVNVPGTKVLSTPQKPTTVNVSATETPPTPQKPTTVNVSATETPPTPQKPTTVNVPATETPPTPEKFITINSSATKPPLVSQTYTTVNVPATKVPSPPQKPSTANGSATTAWNSPISNTVSTAAQNLLMANASATTPTTQRFTPAKSLLIQNLKTTPKSTSVHTTKGLHITQRLTSARVTAAKSTAVPRTTPRFHATGTPQGRGSAPSVASTVASGKCDSLRVHRICHRIRIYNSWKRILFFYCLCCCCSVTKS", "length": 542, "header": "tr|G3X6M2-1|G3X6M2_BOVIN Isoform 1 of CD55 molecule OS=Bos taurus OX=9913 GN=CD55 PE=3 SV=2 CANONICAL=G3X6M2-1" }, "isoforms": [ { "isoform_ac": "G3X6M2-1", "url": "https://www.uniprot.org/uniprotkb/G3X6M2/entry", "sequence": { "sequence": "MGLPPLLRPAPGVRKALAHSSRSQSFGDCSLPPDVPNAQAALGGLTSFPEKRTVTYKCNRGFVKVPGKADSVICENNKWSELAVFCNRSCDVPTRLLFASLKKSYSQQNYFPEGTTVEYECRQGYIRDPSLSGNITCLQNFVWSKPDRFCKKKSCPKPREIENGHVNITTDILLGATIYFSCNAGYKLVGATFSFCAPVGNTVGWTNEFPECQEILCPEPPKVDHGMIQEKQNSYAYGQSVTYKCMEGFTLHGESSIYCTVKDDQGEWSGPLPQCRETDVTPTVPKSTEVNVPGTKVLSTPQKPTTVNVSATETPPTPQKPTTVNVSATETPPTPQKPTTVNVPATETPPTPEKFITINSSATKPPLVSQTYTTVNVPATKVPSPPQKPSTANGSATTAWNSPISNTVSTAAQNLLMANASATTPTTQRFTPAKSLLIQNLKTTPKSTSVHTTKGLHITQRLTSARVTAAKSTAVPRTTPRFHATGTPQGRGSAPSVASTVASGKCDSLRVHRICHRIRIYNSWKRILFFYCLCCCCSVTKS", "length": 542, "header": "tr|G3X6M2-1|G3X6M2_BOVIN Isoform 1 of CD55 molecule OS=Bos taurus OX=9913 GN=CD55 PE=3 SV=2 CANONICAL=G3X6M2-1" }, "locus": { "chromosome": "16", "start_pos": 5269466, "end_pos": 5251900, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000009178.6", "url": "https://www.ensembl.org/id/ENSBTAT00000009178.6" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000009178.6", "url": "https://www.ensembl.org/id/ENSBTAP00000009178.6" } ] } } ], "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "other", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 283, "start_aa": "Thr", "end_pos": 283, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr283", "evidence": [ { "id": "", "database": "GlyGen", "url": "https://data.glygen.org/" } ], "filter_code": "000000000000000010000.00000000001000.0.01000" }, { "glytoucan_ac": "", "type": "O-linked", "subtype": "other", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 351, "start_aa": "Thr", "end_pos": 351, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr351", "evidence": [ { "id": "", "database": "GlyGen", "url": "https://data.glygen.org/" } ], "filter_code": "000000000000000010000.00000000001000.0.01000" } ], "phosphorylation": [], "glycation": [], "keywords": [ "glycoprotein", "glycoprotein_predicted" ], "publication": [], "pathway": [], "orthologs": [], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 1, "go_terms": [ { "name": "membrane", "id": "GO:0016020", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016020", "evidence": [ { "database": "UniProtKB", "id": "G3X6M2", "url": "https://www.uniprot.org/uniprotkb/G3X6M2" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 2, "go_terms": [ { "name": "innate immune response", "id": "GO:0045087", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0045087", "evidence": [ { "database": "UniProtKB", "id": "G3X6M2", "url": "https://www.uniprot.org/uniprotkb/G3X6M2" } ], "pmid": "" }, { "name": "complement activation, classical pathway", "id": "GO:0006958", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006958", "evidence": [ { "database": "UniProtKB", "id": "G3X6M2", "url": "https://www.uniprot.org/uniprotkb/G3X6M2" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 134, "end_pos": 136, "annotation": "n_glycosylation_sequon" }, { "start_pos": 167, "end_pos": 169, "annotation": "n_glycosylation_sequon" }, { "start_pos": 308, "end_pos": 310, "annotation": "n_glycosylation_sequon" }, { "start_pos": 325, "end_pos": 327, "annotation": "n_glycosylation_sequon" }, { "start_pos": 359, "end_pos": 361, "annotation": "n_glycosylation_sequon" }, { "start_pos": 393, "end_pos": 395, "annotation": "n_glycosylation_sequon" }, { "start_pos": 419, "end_pos": 421, "annotation": "n_glycosylation_sequon" }, { "start_pos": 87, "end_pos": 89, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], 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393, "end_pos": 395 }, { "start_pos": 419, "end_pos": 421 }, { "start_pos": 87, "end_pos": 89 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 2 }, { "field": "total_sites", "count": 2 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 2 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "exact_sites", "count": 2 }, { "field": "exact_o_linked_sites", "count": 2 }, { "field": "fuzzy_sites", "count": 0 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_pos", "start_aa", "end_pos", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 2 }, { "field": "total_sites", "count": 2 }, { "field": "n_linked_sites", "count": 0 }, { "field": 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"sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ], "tool_support": { "graph_view": "yes" } }, { "uniprot_canonical_ac": "G3N2G8-1", "uniprot_ac": "G3N2G8", "uniprot_id": "G3N2G8_BOVIN", "mass": { "chemical_mass": 79477.0, "monoisotopic_mass": 79477.0 }, "refseq": {}, "gene_names": [ { "name": "LOC132342105", "type": "recommended", "evidence": [ { "id": "G3N2G8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3N2G8" } ] } ], "protein_names": [ { "name": "Zinc finger protein 271", "type": "recommended", "evidence": [ { "id": "G3N2G8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3N2G8/entry#names_and_taxonomy" } ] } ], "function": [], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Bos taurus", "taxid": 9913, "evidence": [ { "database": "UniProtKB", "id": "G3N2G8", "url": "https://www.uniprot.org/uniprotkb/G3N2G8" } ], "common_name": "Bovine", "glygen_name": "Bovine", "reference_species": "Bos taurus [9913]" } ], "gene": [ { "name": "LOC132342105", "url": "https://www.uniprot.org/uniprotkb/G3N2G8", "locus": {} } ], "crossref": [ { "id": "G3N2G8", "url": "https://alphafold.ebi.ac.uk/entry/G3N2G8", "database": "AlphaFoldDB", "categories": [] }, { "id": "ENSBTAG00000010252", "url": "https://bgee.org/?page=gene&gene_id=ENSBTAG00000010252", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "132342105", "url": "https://www.ncbi.nlm.nih.gov/gene/132342105", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR013087", "url": "https://www.ebi.ac.uk/interpro/entry/IPR013087", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR036236", "url": "https://www.ebi.ac.uk/interpro/entry/IPR036236", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "bta:132342105", "url": "https://www.genome.jp/dbget-bin/www_bget?bta:132342105", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "G3N2G8", "url": "https://www.orthodb.org/?gene=G3N2G8", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR23235", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR23235", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR23235:SF178", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR23235:SF178", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR24394", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR24394", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR24394:SF48", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR24394:SF48", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00096", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00096", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF13912", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF13912", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "A0AAA9TDV6", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TDV6", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0AAA9TDV6-1", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TDV6-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "G3N2G8", "url": "https://www.uniprot.org/uniprotkb/G3N2G8", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "G3N2G8-1", "url": "https://www.uniprot.org/uniprotkb/G3N2G8-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MNIRNFGSKWNPEAWMQPHESADEDGVTKSSVGEMASKEEITAKIEPLTEESGNPRNDVLQDPECREFFGLGDKFSEKDQNLFKRRQHNCDECGQSFACSTGLIRHRRTHWEKPYECDQCGKAFNVSSALVLHQRIHTGEKPYPCNWCIKSFSRSSDLIKHQRVHTGEKPYKCDECGKAFSQSSDLIIHQRIHTGEKPYQCGHCSKSFSQRSDLIKHQRIHTGEKPYTCSLCNKHFSQSSDVIKHQRIHTGEKPYKCDVCGKAFSQSSDLILHQRIHTGEKPYRCNQCNKSFSQNSDLIKHRRIHTGEKPYKCNECGKAFNQSSVLILHQRIHTGEKPYPCNQCSKTFSRLSDLINHQRIHTGEKPYPCNQCSKTFSRRSDLIKHYRIHTGEKPYECDECGKTFSQSSNLILHQRIHTGEKPYPCSDCTKSFSRRSDLVKHQRIHTGEKPYTCNQCNKSFSQSSDLIKHQRVHSGEKPYHCDCCERAFSQSSDLILHQRIHTGEKPYACTQCSKSFSQNSDLIKHQRIHTGEKPYKCNECGKAFSQCSALVLHQRIHTGEKPYPCGQCGKGFSRRSDLINHQRIHTNENPYKCDVCRKAFSTSTDLTEHQRIHMREKPHRCVQCNRSFSQLSDLNHHEKIHSGEDTLNVGKPLVYTPTLFSTRDALPEKNLRNAIDYEKGFNQCSAVTLH", "length": 690, "header": "tr|G3N2G8-1|G3N2G8_BOVIN Isoform 1 of Zinc finger protein 271 OS=Bos taurus OX=9913 GN=LOC132342105 PE=3 SV=3 CANONICAL=G3N2G8-1" }, "isoforms": [ { "isoform_ac": "A0AAA9TDV6-1", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TDV6/entry", "sequence": { "sequence": "MASKEEITAKIEPLTEESGNPRNDVLQDPECREFFGLGDKFSEKDQNLFKRRQHNCDECGQSFACSTGLIRHRRTHWEKPYECDQCGKAFNVSSALVLHQRIHTGEKPYPCNWCIKSFSRSSDLIKHQRVHTGEKPYKCDECGKAFSQSSDLIIHQRIHTGEKPYQCGHCSKSFSQRSDLIKHQRIHTGEKPYTCSLCNKHFSQSSDVIKHQRIHTGEKPYKCDVCGKAFSQSSDLILHQRIHTGEKPYRCNQCNKSFSQNSDLIKHRRIHTGEKPYKCNECGKAFNQSSVLILHQRIHTGEKPYPCNQCSKTFSRLSDLINHQRIHTGEKPYPCNQCSKTFSRRSDLIKHYRIHTGEKPYECDECGKTFSQSSNLILHQRIHTGEKPYPCSDCTKSFSRRSDLVKHQRIHTGEKPYTCNQCNKSFSQSSDLIKHQRVHSGEKPYHCDCCERAFSQSSDLILHQRIHTGEKPYACTQCSKSFSQNSDLIKHQRIHTGEKPYKCNECGKAFSQCSALVLHQRIHTGEKPYPCGQCGKGFSRRSDLINHQRIHTNENPYKCDVCRKAFSTSTDLTEHQRIHMREKPHRCVQCNRSFSQLSDLNHHEKIHSGEDTLNVGKPLVYTPTLFSTRDALPEKNLRNAIDYEKGFNQCSAVTLH", "length": 656, "header": "tr|A0AAA9TDV6-1|G3N2G8_BOVIN Computationally mapped isoform of Zinc finger protein 271 OS=Bos taurus OX=9913 GN=LOC132342105 PE=3 SV=1 CANONICAL=G3N2G8-1" }, "locus": { "chromosome": "24", "start_pos": 21738898, "end_pos": 21736931, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000135362.1", "url": "https://www.ensembl.org/id/ENSBTAT00000135362.1" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000082264.1", "url": "https://www.ensembl.org/id/ENSBTAP00000082264.1" } ] } }, { "isoform_ac": "G3N2G8-1", "url": "https://www.uniprot.org/uniprotkb/G3N2G8/entry", "sequence": { "sequence": "MNIRNFGSKWNPEAWMQPHESADEDGVTKSSVGEMASKEEITAKIEPLTEESGNPRNDVLQDPECREFFGLGDKFSEKDQNLFKRRQHNCDECGQSFACSTGLIRHRRTHWEKPYECDQCGKAFNVSSALVLHQRIHTGEKPYPCNWCIKSFSRSSDLIKHQRVHTGEKPYKCDECGKAFSQSSDLIIHQRIHTGEKPYQCGHCSKSFSQRSDLIKHQRIHTGEKPYTCSLCNKHFSQSSDVIKHQRIHTGEKPYKCDVCGKAFSQSSDLILHQRIHTGEKPYRCNQCNKSFSQNSDLIKHRRIHTGEKPYKCNECGKAFNQSSVLILHQRIHTGEKPYPCNQCSKTFSRLSDLINHQRIHTGEKPYPCNQCSKTFSRRSDLIKHYRIHTGEKPYECDECGKTFSQSSNLILHQRIHTGEKPYPCSDCTKSFSRRSDLVKHQRIHTGEKPYTCNQCNKSFSQSSDLIKHQRVHSGEKPYHCDCCERAFSQSSDLILHQRIHTGEKPYACTQCSKSFSQNSDLIKHQRIHTGEKPYKCNECGKAFSQCSALVLHQRIHTGEKPYPCGQCGKGFSRRSDLINHQRIHTNENPYKCDVCRKAFSTSTDLTEHQRIHMREKPHRCVQCNRSFSQLSDLNHHEKIHSGEDTLNVGKPLVYTPTLFSTRDALPEKNLRNAIDYEKGFNQCSAVTLH", "length": 690, "header": "tr|G3N2G8-1|G3N2G8_BOVIN Isoform 1 of Zinc finger protein 271 OS=Bos taurus OX=9913 GN=LOC132342105 PE=3 SV=3 CANONICAL=G3N2G8-1" }, "locus": { "chromosome": "24", "start_pos": 21747719, "end_pos": 21736931, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000065936.3", "url": "https://www.ensembl.org/id/ENSBTAT00000065936.3" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000056080.3", "url": "https://www.ensembl.org/id/ENSBTAP00000056080.3" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [ { "id": "bta:132342105", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?bta:132342105", "resource": "KEGG Pathway" } ], "orthologs": [], "go_annotation": { "categories": [ { "name": "Molecular Function", "total": 4, "go_terms": [ { "name": "DNA binding", "id": "GO:0003677", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003677", "evidence": [ { "database": "UniProtKB", "id": "G3N2G8", "url": "https://www.uniprot.org/uniprotkb/G3N2G8" } ], "pmid": "" }, { "name": "zinc ion binding", "id": "GO:0008270", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008270", "evidence": [ { "database": "UniProtKB", "id": "G3N2G8", "url": "https://www.uniprot.org/uniprotkb/G3N2G8" } ], "pmid": "" }, { "name": "RNA polymerase II cis-regulatory region sequence-specific DNA binding", "id": "GO:0000978", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000978", "evidence": [ { "database": "UniProtKB", "id": "G3N2G8", "url": "https://www.uniprot.org/uniprotkb/G3N2G8" } ], "pmid": "" }, { "name": "DNA-binding transcription factor activity, RNA polymerase II-specific", "id": "GO:0000981", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000981", "evidence": [ { "database": "UniProtKB", "id": "G3N2G8", "url": "https://www.uniprot.org/uniprotkb/G3N2G8" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 1, "go_terms": [ { "name": "nucleoplasm", "id": "GO:0005654", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005654", "evidence": [ { "database": "UniProtKB", "id": "G3N2G8", "url": "https://www.uniprot.org/uniprotkb/G3N2G8" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 2, "go_terms": [ { "name": "DNA-templated transcription", "id": "GO:0006351", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006351", "evidence": [ { "database": "UniProtKB", "id": "G3N2G8", "url": "https://www.uniprot.org/uniprotkb/G3N2G8" } ], "pmid": "" }, { "name": "regulation of transcription by RNA polymerase II", "id": "GO:0006357", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006357", "evidence": [ { "database": "UniProtKB", "id": "G3N2G8", "url": "https://www.uniprot.org/uniprotkb/G3N2G8" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 125, "end_pos": 127, "annotation": "n_glycosylation_sequon" }, { "start_pos": 289, "end_pos": 291, "annotation": "n_glycosylation_sequon" }, { "start_pos": 321, "end_pos": 323, "annotation": "n_glycosylation_sequon" }, { "start_pos": 457, "end_pos": 459, "annotation": "n_glycosylation_sequon" }, { "start_pos": 625, "end_pos": 627, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [ { "pdb_id": "AF-G3N2G8-F1", "pdb_chain": "global", "start_pos": 1, "end_pos": 690, "overlap": "1.0", "method": "AlphaFold", "type": "alphafold", "resolution": -1.0, "url": "https://data.glygen.org/ln2downloads/pdb/current/AF-G3N2G8-F1.pdb", "url_external": "https://alphafold.ebi.ac.uk/entry/G3N2G8" } ], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "G3N2G8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3N2G8" }, { "id": "PS50157", "database": "PROSITE", "url": "https://prosite.expasy.org/PS50157" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "C2H2-type", "eco_id": "ECO_0000259", "start_pos": 88, "end_pos": 110, "start_aa": "His", "end_aa": "His", "glycosite_overlap": [] } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 125, "end_pos": 127 }, { "start_pos": 289, "end_pos": 291 }, { "start_pos": 321, "end_pos": 323 }, { "start_pos": 457, "end_pos": 459 }, { "start_pos": 625, "end_pos": 627 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": 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"total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ], "tool_support": { "graph_view": "yes" } }, { "uniprot_canonical_ac": "G3N2I2-1", "uniprot_ac": "G3N2I2", "uniprot_id": "G3N2I2_BOVIN", "mass": { "chemical_mass": 65873.0, "monoisotopic_mass": 65873.0 }, "refseq": {}, "gene_names": [ { "name": "C11H2orf81", "type": "recommended", "evidence": [ { "id": "G3N2I2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3N2I2" } ] } ], "protein_names": [ { "name": "Chromosome 11 C2orf81 homolog", "type": "synonym", "evidence": [ { "id": "G3N2I2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3N2I2/entry#names_and_taxonomy" } ] } ], "function": [], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Bos taurus", "taxid": 9913, "evidence": [ { "database": "UniProtKB", "id": "G3N2I2", "url": "https://www.uniprot.org/uniprotkb/G3N2I2" } ], "common_name": "Bovine", "glygen_name": "Bovine", "reference_species": "Bos taurus [9913]" } ], "gene": [ { "name": "C11H2orf81", "url": "https://www.uniprot.org/uniprotkb/G3N2I2", "locus": { "chromosome": "11", "start_pos": 10211683, "end_pos": 10205805, "strand": "-", "evidence": [ { "database": "Ensembl Gene", "id": "ENSBTAG00000040226", "url": "https://www.ensembl.org/id/ENSBTAG00000040226" } ] } } ], "crossref": [ { "id": "G3N2I2", "url": "https://alphafold.ebi.ac.uk/entry/G3N2I2", "database": "AlphaFoldDB", "categories": [] }, { "id": "ENSBTAG00000040226", "url": "https://bgee.org/?page=gene&gene_id=ENSBTAG00000040226", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "789060", "url": "https://www.ncbi.nlm.nih.gov/gene/789060", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR028042", "url": "https://www.ebi.ac.uk/interpro/entry/IPR028042", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "bta:789060", "url": "https://www.genome.jp/dbget-bin/www_bget?bta:789060", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "G3N2I2", "url": "https://www.orthodb.org/?gene=G3N2I2", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR34438", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR34438", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR34438:SF1", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR34438:SF1", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF15479", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF15479", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "NP_001103658", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001103658", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0AAA9TE32", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TE32", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0AAA9TE32-1", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TE32-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "G3N2I2", "url": "https://www.uniprot.org/uniprotkb/G3N2I2", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "G3N2I2-1", "url": "https://www.uniprot.org/uniprotkb/G3N2I2-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MAHEGPRQVRDRGMTRSKAEKVRPPTVPVPQVDIVPGRLTEAEWIAFTALEEGEDVVGDILADLVARVIDSAFKVYLTQQCIPFTISQAREAMLQITEWRFLARDEGESAVAEDPTWGEDEEPLACTTDAWAQGSVPVLHARASMGLEETFQGEDQDSVDQIPLGGSWTDSGSQEPMESWELTVTPDSPPTPELLQETGPRSPLEKLGDQSRSDQTDLFAVGSSNSSSQLSMEMVPAGSTHASLELSLVASPQASVERAQPISSQFSLEDLYNCTPQPHAAGDRLELREEKVPLIPSRVLVSDPSAGGPTTLNPSAGFQPQPPWLAEERPSALHSRIGRKGTTARLDPARLPRPWVRPLSEVLVPDSEGRPLEAYRGRQRGEKTEAPAGPQASRPSCRVSRSEFFPFPPGVPVRTLGPGLSLQFPTLNLGLPSPGFGSKLPFPSPGLRFLATHRARPDMARSPSPKLWPGAKWPSGWEGEAELLGELWAGRTRVPPQGLDLGDRESQDPHQYRHPVPQVLEATSQVTWKPVLLPGALKLAPGVSMWNPSTQVLLSSSEPQRNDREGSASPPIHTGAPKPQVTVAQLMNSALKMWSLPSKRLPNSKP", "length": 606, "header": "tr|G3N2I2-1|G3N2I2_BOVIN Isoform 1 of Chromosome 11 C2orf81 homolog OS=Bos taurus OX=9913 GN=C11H2orf81 PE=4 SV=1 CANONICAL=G3N2I2-1" }, "isoforms": [ { "isoform_ac": "A0AAA9TE32-1", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TE32/entry", "sequence": { "sequence": "SAHQRQVRDRGMTRSKAEKVRPPTVPVPQVDIVPGRLTEAEWIAFTALEEGEDVVGDILADLVARVIDSAFKVYLTQQCIPFTISQAREAMLQITEWRFLARDEGESAVAEDPTWGEDEEPLACTTDAWAQGSVPVLHARASMGLEETFQGEDQDSVDQIPLGGSWTDSGSQEPMESWELTVTPDSPPTPELLQETGPRSPLEKLGDQSRSDQTDLFAVGSSNSSSQLSMEMVPAGSTHASLELSLVASPQASVERAQPISSQFSLEDLYNCTPQPHAAGDRLELREEKVPLIPSRVLVSDPSAGGPTTLNPSAGFQPQPPWLAEERPSALHSRIGRKGTTARLDPARLPRPWVRPPSPKLWPGAKWPSGWEGEAELLGELWAGRTRVPPQGLDLGDRESQDPHQYRHPVPQVLEATSQVTWKPVLLPGALKLAPGVSMWNPSTQVLLSSSEPQRNDREGSASPPIHTGAPKPQVTVAQLMNSALKMWSLPSKRLPNSKP", "length": 500, "header": "tr|A0AAA9TE32-1|G3N2I2_BOVIN Computationally mapped isoform of Chromosome 11 C2orf81 homolog OS=Bos taurus OX=9913 GN=C11H2orf81 PE=4 SV=1 CANONICAL=G3N2I2-1" }, "locus": { "chromosome": "11", "start_pos": 10211620, "end_pos": 10208907, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000089775.1", "url": "https://www.ensembl.org/id/ENSBTAT00000089775.1" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000096409.1", "url": "https://www.ensembl.org/id/ENSBTAP00000096409.1" } ] } }, { "isoform_ac": "G3N2I2-1", "url": "https://www.uniprot.org/uniprotkb/G3N2I2/entry", "sequence": { "sequence": "MAHEGPRQVRDRGMTRSKAEKVRPPTVPVPQVDIVPGRLTEAEWIAFTALEEGEDVVGDILADLVARVIDSAFKVYLTQQCIPFTISQAREAMLQITEWRFLARDEGESAVAEDPTWGEDEEPLACTTDAWAQGSVPVLHARASMGLEETFQGEDQDSVDQIPLGGSWTDSGSQEPMESWELTVTPDSPPTPELLQETGPRSPLEKLGDQSRSDQTDLFAVGSSNSSSQLSMEMVPAGSTHASLELSLVASPQASVERAQPISSQFSLEDLYNCTPQPHAAGDRLELREEKVPLIPSRVLVSDPSAGGPTTLNPSAGFQPQPPWLAEERPSALHSRIGRKGTTARLDPARLPRPWVRPLSEVLVPDSEGRPLEAYRGRQRGEKTEAPAGPQASRPSCRVSRSEFFPFPPGVPVRTLGPGLSLQFPTLNLGLPSPGFGSKLPFPSPGLRFLATHRARPDMARSPSPKLWPGAKWPSGWEGEAELLGELWAGRTRVPPQGLDLGDRESQDPHQYRHPVPQVLEATSQVTWKPVLLPGALKLAPGVSMWNPSTQVLLSSSEPQRNDREGSASPPIHTGAPKPQVTVAQLMNSALKMWSLPSKRLPNSKP", "length": 606, "header": "tr|G3N2I2-1|G3N2I2_BOVIN Isoform 1 of Chromosome 11 C2orf81 homolog OS=Bos taurus OX=9913 GN=C11H2orf81 PE=4 SV=1 CANONICAL=G3N2I2-1" }, "locus": { "chromosome": "11", "start_pos": 10211620, "end_pos": 10205905, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000063282.3", "url": "https://www.ensembl.org/id/ENSBTAT00000063282.3" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000056097.1", "url": "https://www.ensembl.org/id/ENSBTAP00000056097.1" } ] } } ], "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "other", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 116, "start_aa": "Thr", "end_pos": 116, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr116", "evidence": [ { "id": "", "database": "GlyGen", "url": "https://data.glygen.org/" } ], "filter_code": "000000000000000010000.00000000001000.0.01000" }, { "glytoucan_ac": "", "type": "O-linked", "subtype": "other", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 191, "start_aa": "Thr", "end_pos": 191, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr191", "evidence": [ { "id": "", "database": "GlyGen", "url": "https://data.glygen.org/" } ], "filter_code": "000000000000000010000.00000000001000.0.01000" } ], "phosphorylation": [], "glycation": [], "keywords": [ "glycoprotein", "glycoprotein_predicted" ], "publication": [], "pathway": [ { "id": "bta:789060", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?bta:789060", "resource": "KEGG Pathway" } ], "orthologs": [], "go_annotation": {}, "pro_annotation": [], "site_annotation": [ { "start_pos": 225, "end_pos": 227, "annotation": "n_glycosylation_sequon" }, { "start_pos": 273, "end_pos": 275, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [ { "pdb_id": "AF-G3N2I2-F1", "pdb_chain": "global", "start_pos": 1, "end_pos": 606, "overlap": "1.0", "method": "AlphaFold", "type": "alphafold", "resolution": -1.0, "url": "https://data.glygen.org/ln2downloads/pdb/current/AF-G3N2I2-F1.pdb", "url_external": "https://alphafold.ebi.ac.uk/entry/G3N2I2" } ], "lectin_list": [], "domain_list": [], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [ 116, 191 ], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 225, "end_pos": 227 }, { "start_pos": 273, "end_pos": 275 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 2 }, { 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"MAAAAALMDTAQGCVTFEDVTIYFSPEEWGLLDEAQRLLYCDVMLENFALIASLGLASFRSHIVAQLEMGAEPWVPDQADMTSAMARGVYRGLGSDFYCGTESEESPAELSVSVEVSQNMNSKAVSSTQKGYPCNLCGLHLKDILYLAKHRATHSKQKPHVHEAHRKELKFNAHFHQPQMQQNVDKSIGRNEGRALLVKSFRYDTSKKSFTFRENGKASVARCGFLQHQVTTSVGEPEQSSESVVDFPTVQLHKKCSEFENAVSDKLSLVQQRTHTGERSYECNKCGIFFSCAAGLFQHQRDHNRGKPYECGECGKFFSQHSSLIKHQRVHTGESPHVCSECGKFFSRSSNLIQHKRVHTGEKPYECSECGKFFRQRSNLIHHKRIHTGKSAHECSECGKSFNCNSSLIKHWRVHTGEKPYKCNECGKFFSRFDGLVQHQIVHTGERPYRCSVCGKAFRRSSDLMNHQRVHTGERPYECSECGKTFRRSSNLRQHRKVHKPDKTYKCNECGKAFSQRSTLIQHQKIHAREKSTKDVLPPSAQQHLLEMNSESGLYEGAVSQKLNLVHPNIYAGEIPNGC", "length": 579, "header": "tr|G3X713-1|G3X713_BOVIN Isoform 1 of Zinc finger protein 792 OS=Bos taurus OX=9913 GN=ZNF792 PE=3 SV=3 CANONICAL=G3X713-1" }, "isoforms": [ { "isoform_ac": "A0AAA9TEW0-1", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TEW0/entry", "sequence": { "sequence": 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"https://www.ensembl.org/id/ENSBTAT00000098837.1" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000095366.1", "url": "https://www.ensembl.org/id/ENSBTAP00000095366.1" } ] } }, { "isoform_ac": "G3X713-1", "url": "https://www.uniprot.org/uniprotkb/G3X713/entry", "sequence": { "sequence": "MAAAAALMDTAQGCVTFEDVTIYFSPEEWGLLDEAQRLLYCDVMLENFALIASLGLASFRSHIVAQLEMGAEPWVPDQADMTSAMARGVYRGLGSDFYCGTESEESPAELSVSVEVSQNMNSKAVSSTQKGYPCNLCGLHLKDILYLAKHRATHSKQKPHVHEAHRKELKFNAHFHQPQMQQNVDKSIGRNEGRALLVKSFRYDTSKKSFTFRENGKASVARCGFLQHQVTTSVGEPEQSSESVVDFPTVQLHKKCSEFENAVSDKLSLVQQRTHTGERSYECNKCGIFFSCAAGLFQHQRDHNRGKPYECGECGKFFSQHSSLIKHQRVHTGESPHVCSECGKFFSRSSNLIQHKRVHTGEKPYECSECGKFFRQRSNLIHHKRIHTGKSAHECSECGKSFNCNSSLIKHWRVHTGEKPYKCNECGKFFSRFDGLVQHQIVHTGERPYRCSVCGKAFRRSSDLMNHQRVHTGERPYECSECGKTFRRSSNLRQHRKVHKPDKTYKCNECGKAFSQRSTLIQHQKIHAREKSTKDVLPPSAQQHLLEMNSESGLYEGAVSQKLNLVHPNIYAGEIPNGC", "length": 579, "header": "tr|G3X713-1|G3X713_BOVIN Isoform 1 of Zinc finger protein 792 OS=Bos taurus OX=9913 GN=ZNF792 PE=3 SV=3 CANONICAL=G3X713-1" }, "locus": { "chromosome": "18", "start_pos": 45711332, "end_pos": 45697197, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000017105.7", "url": "https://www.ensembl.org/id/ENSBTAT00000017105.7" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000017105.7", "url": "https://www.ensembl.org/id/ENSBTAP00000017105.7" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [ { "id": "bta:519314", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?bta:519314", "resource": "KEGG Pathway" }, { "id": "R-BTA-212436", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-BTA-212436", "resource": "Reactome", "description": "Generic Transcription Pathway" } ], "orthologs": [], "go_annotation": { "categories": [ { "name": "Molecular Function", "total": 5, "go_terms": [ { "name": "DNA binding", "id": "GO:0003677", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003677", "evidence": [ { "database": "UniProtKB", "id": "G3X713", "url": "https://www.uniprot.org/uniprotkb/G3X713" } ], "pmid": "" }, { "name": "zinc ion binding", "id": "GO:0008270", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008270", "evidence": [ { "database": "UniProtKB", "id": "G3X713", "url": "https://www.uniprot.org/uniprotkb/G3X713" } ], "pmid": "" }, { "name": "identical protein binding", "id": "GO:0042802", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0042802", "evidence": [ { "database": "UniProtKB", "id": "G3X713", "url": "https://www.uniprot.org/uniprotkb/G3X713" } ], "pmid": "" }, { "name": "RNA polymerase II cis-regulatory region sequence-specific DNA binding", "id": "GO:0000978", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000978", "evidence": [ { "database": "UniProtKB", "id": "G3X713", "url": "https://www.uniprot.org/uniprotkb/G3X713" } ], "pmid": "" }, { "name": "DNA-binding transcription factor activity, RNA polymerase II-specific", "id": "GO:0000981", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000981", "evidence": [ { "database": "UniProtKB", "id": "G3X713", "url": "https://www.uniprot.org/uniprotkb/G3X713" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 1, "go_terms": [ { "name": "nucleus", "id": "GO:0005634", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005634", "evidence": [ { "database": "UniProtKB", "id": "G3X713", "url": "https://www.uniprot.org/uniprotkb/G3X713" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 3, "go_terms": [ { "name": "DNA-templated transcription", "id": "GO:0006351", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006351", "evidence": [ { "database": "UniProtKB", "id": "G3X713", "url": "https://www.uniprot.org/uniprotkb/G3X713" } ], "pmid": "" }, { "name": "negative regulation of DNA-templated transcription", "id": "GO:0045892", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0045892", "evidence": [ { "database": "UniProtKB", "id": "G3X713", "url": "https://www.uniprot.org/uniprotkb/G3X713" } ], "pmid": "" }, { "name": "regulation of transcription by RNA polymerase II", "id": "GO:0006357", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006357", "evidence": [ { "database": "UniProtKB", "id": "G3X713", "url": "https://www.uniprot.org/uniprotkb/G3X713" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 405, "end_pos": 407, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [ { "pdb_id": "AF-G3X713-F1", "pdb_chain": "global", "start_pos": 1, "end_pos": 579, "overlap": "1.0", "method": "AlphaFold", "type": "alphafold", "resolution": -1.0, "url": "https://data.glygen.org/ln2downloads/pdb/current/AF-G3X713-F1.pdb", "url_external": "https://alphafold.ebi.ac.uk/entry/G3X713" } ], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "G3X713", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3X713" }, { "id": "PS50157", "database": "PROSITE", "url": "https://prosite.expasy.org/PS50157" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "C2H2-type", "eco_id": "ECO_0000259", "start_pos": 132, "end_pos": 159, "start_aa": "Tyr", "end_aa": "Pro", "glycosite_overlap": [] }, { "evidence": [ { "id": "G3X713", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3X713" }, { "id": "PS50805", "database": "PROSITE", "url": "https://prosite.expasy.org/PS50805" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "KRAB", "eco_id": "ECO_0000259", "start_pos": 15, "end_pos": 86, "start_aa": "Val", "end_aa": "Ala", "glycosite_overlap": [] } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 405, "end_pos": 407 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ], "tool_support": { "graph_view": "yes" } }, { "uniprot_canonical_ac": "G3N1G1-1", "uniprot_ac": "G3N1G1", "uniprot_id": "G3N1G1_BOVIN", "mass": { "chemical_mass": 50342.0, "monoisotopic_mass": 50342.0 }, "refseq": { "ac": "NP_001421817", "name": "RUS family member 1", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001421817" }, "gene_names": [ { "name": "RUSF1", "type": "recommended", "evidence": [ { "id": "G3N1G1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3N1G1" } ] }, { "name": "C25H16orf58", "type": "synonym", "evidence": [ { "id": "NP_001421817", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001421817" } ] }, { "name": "RUSF1", "type": "synonym", "evidence": [ { "id": "NP_001421817", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001421817" } ] } ], "protein_names": [ { "name": "RUS family member 1", "type": "synonym", "evidence": [ { "id": "NP_001421817", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001421817" }, { "id": "G3N1G1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3N1G1/entry#names_and_taxonomy" } ] }, { "name": "chromosome 25 C16orf58 homolog", "type": "synonym", "evidence": [ { "id": "NP_001421817", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001421817" } ] } ], "function": [], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Bos taurus", "taxid": 9913, "evidence": [ { "database": "UniProtKB", "id": "G3N1G1", "url": "https://www.uniprot.org/uniprotkb/G3N1G1" } ], "common_name": "Bovine", "glygen_name": "Bovine", "reference_species": "Bos taurus [9913]" } ], "gene": [ { "name": "RUSF1", "url": "https://www.uniprot.org/uniprotkb/G3N1G1", "locus": { "chromosome": "25", "start_pos": 27522807, "end_pos": 27538289, "strand": "+", "evidence": [ { "database": "Ensembl Gene", "id": "ENSBTAG00000047734", "url": "https://www.ensembl.org/id/ENSBTAG00000047734" } ] } } ], "crossref": [ { "id": "G3N1G1", "url": "https://alphafold.ebi.ac.uk/entry/G3N1G1", "database": "AlphaFoldDB", "categories": [] }, { "id": "ENSBTAG00000047734", "url": "https://bgee.org/?page=gene&gene_id=ENSBTAG00000047734", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "767862", "url": "https://www.ncbi.nlm.nih.gov/gene/767862", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR006968", "url": "https://www.ebi.ac.uk/interpro/entry/IPR006968", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR054549", "url": "https://www.ebi.ac.uk/interpro/entry/IPR054549", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR055412", "url": "https://www.ebi.ac.uk/interpro/entry/IPR055412", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "VAVQWII", "url": "https://omabrowser.org/oma/group/VAVQWII/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "PTHR12770", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR12770", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR12770:SF31", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR12770:SF31", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF04884", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF04884", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF24160", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF24160", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "NP_001421817", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001421817", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0AAA9TGZ5", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TGZ5", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0AAA9TGZ5-1", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TGZ5-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "G3N1G1", "url": "https://www.uniprot.org/uniprotkb/G3N1G1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "G3N1G1-1", "url": "https://www.uniprot.org/uniprotkb/G3N1G1-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MADVLCSEQFGSGAARGCRAAPDGSLQWEAWGRRWWGFSGAFTAKPGGRDGGGGVAPGTASPPFSRLLAVFLPQGFPDSVSPDYLPYQLWDSVQAFASSLSGSLATHAVLLGIGVGDAKASVSAATATWLVKDSTGMLGRIVFAWWMGSKMDCNAKQWRLFADILNDIAMFLEIMAPILPFCFTITVCISNLAKCLVGVAGGATRAALTMHQARRNNMADVSAKDGSQETLVNLAGLLVSLLMLPLVSDSPSLSLGCFFFLTALHIYANYRAVRALVIETLNEQRLWLVLRHFLQRGEVLGPTSANQMEPLWTGFWSSVSLSLGAPLHRVTSSVSELQQLVEGHQEPYLLRWDQSRNQVQVVLSQMAGPKAILRAATHGLVLGALRGDGPLPEELEELRNQAQAGPEKESWVVVRETHQVLDKLFPKFLKGLQDAGWSTEKHQLEVDEWRATWLLCPEKKVL", "length": 462, "header": "tr|G3N1G1-1|G3N1G1_BOVIN Isoform 1 of RUS family member 1 OS=Bos taurus OX=9913 GN=RUSF1 PE=3 SV=2 CANONICAL=G3N1G1-1" }, "isoforms": [ { "isoform_ac": "A0AAA9TGZ5-1", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TGZ5/entry", "sequence": { "sequence": "MADVLCSEQFGSGAARGCRAAPDGSLQWEGFPDSVSPDYLPYQLWDSVQAFASSLSGSLATHAVLLGIGVGDAKASVSAATATWLVKDSTGMLGRIVFAWWMGSKMDCNAKQWRLFADILNDIAMFLEIMAPILPFCFTITVCISNLAKCLVGVAGGATRAALTMHQARRNNMADVSAKDGSQETLVNLAGLLVSLLMLPLVSDSPSLSLGCFFFLTALHIYANYRAVRALVIETLNEQRLWLVLRHFLQRGEVLGPTSANQMEPLWTGFWSSVSLSLGAPLHRVTSSVSELQQLVEGHQEPYLLRWDQSRNQVQVVLSQMAGPKAILRAATHGLVLGALRGDGPLPEELEELRNQAQAGPEKESWVVVRETHQVLDKLFPKFLKGLQDAGWSTEKHQLEVDEWRATWLLCPEKKVL", "length": 417, "header": "tr|A0AAA9TGZ5-1|G3N1G1_BOVIN Computationally mapped isoform of RUS family member 1 OS=Bos taurus OX=9913 GN=RUSF1 PE=3 SV=1 CANONICAL=G3N1G1-1" }, "locus": { "chromosome": "25", "start_pos": 27537894, "end_pos": 27523811, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000109836.1", "url": "https://www.ensembl.org/id/ENSBTAT00000109836.1" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000097494.1", "url": "https://www.ensembl.org/id/ENSBTAP00000097494.1" } ] } }, { "isoform_ac": "G3N1G1-1", "url": "https://www.uniprot.org/uniprotkb/G3N1G1/entry", "sequence": { "sequence": "MADVLCSEQFGSGAARGCRAAPDGSLQWEAWGRRWWGFSGAFTAKPGGRDGGGGVAPGTASPPFSRLLAVFLPQGFPDSVSPDYLPYQLWDSVQAFASSLSGSLATHAVLLGIGVGDAKASVSAATATWLVKDSTGMLGRIVFAWWMGSKMDCNAKQWRLFADILNDIAMFLEIMAPILPFCFTITVCISNLAKCLVGVAGGATRAALTMHQARRNNMADVSAKDGSQETLVNLAGLLVSLLMLPLVSDSPSLSLGCFFFLTALHIYANYRAVRALVIETLNEQRLWLVLRHFLQRGEVLGPTSANQMEPLWTGFWSSVSLSLGAPLHRVTSSVSELQQLVEGHQEPYLLRWDQSRNQVQVVLSQMAGPKAILRAATHGLVLGALRGDGPLPEELEELRNQAQAGPEKESWVVVRETHQVLDKLFPKFLKGLQDAGWSTEKHQLEVDEWRATWLLCPEKKVL", "length": 462, "header": "tr|G3N1G1-1|G3N1G1_BOVIN Isoform 1 of RUS family member 1 OS=Bos taurus OX=9913 GN=RUSF1 PE=3 SV=2 CANONICAL=G3N1G1-1" }, "locus": { "chromosome": "25", "start_pos": 27537894, "end_pos": 27523811, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000065138.3", "url": "https://www.ensembl.org/id/ENSBTAT00000065138.3" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000055704.2", "url": "https://www.ensembl.org/id/ENSBTAP00000055704.2" } ] } } ], "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "other", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 303, "start_aa": "Thr", "end_pos": 303, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr303", "evidence": [ { "id": "", "database": "GlyGen", "url": "https://data.glygen.org/" } ], "filter_code": "000000000000000010000.00000000001000.0.01000" } ], "phosphorylation": [], "glycation": [], "keywords": [ "glycoprotein", "glycoprotein_predicted" ], "publication": [], "pathway": [], "orthologs": [ { "uniprot_canonical_ac": "A0A8V0X8J2-1", "protein_name": "RUS family member 1", "gene_name": "LOC121108155", "tax_id": 9031, "organism": "Gallus gallus", "sequence": { "sequence": "MAELSGPTPPCRKGALRRAAERVLLPSGFPHSVSPDYLQYQCWDSAQALCSSLSGIIATRAVFEAVGVGDGAATPMGATLTWLLRDGVGMVTRIAFASIQGSALDCEAKQWRLAADVINDAALLLELSAPAWPGAAPLVLAGAAAARSVVGVAGGATRAAIAVHQARRDNAAEVAAKDGSQETVVNALGLLLALLLLPVLEGRPWLTWLLVLLLTAAHLGANMAAVRSLCIPTLNRPRLRLALSGALRGLSGALRGPTDPKSPTPNKGGVTVAVPTPREVNPKEPLLPGFSSRLRLRLGAPKQSLVGSEAEFRKAVECGSPDYIIVLRPSQGWVGVGLRDGAPPDAPLRGCAHALLLEELLGADLPPMAPMGAALRPLQQRLRRCPPGSVPWATLAEISRLWDTLGPAFLRGLEDAGWSTRRHQLAADEWRLQWAGPRPESHAHPSLTTPT", "length": 451 }, "evidence": [ { "id": "G3N1G1", "url": "https://omabrowser.org/oma/group/G3N1G1/", "database": "OMA" } ], "glygen_name": "Chicken", "common_name": "Chicken" }, { "uniprot_canonical_ac": "A0AC58IT11-1", "protein_name": "RUS family member 1 isoform X1", "gene_name": "rusf1", "tax_id": 7955, "organism": "Danio rerio", "sequence": { "sequence": "MYMQPETTMVEMEESEGVIATERYGSQESWKYLLKEGKVMRRKDAVNGGLAANSVSGVFKSVFLPQGYPESVSEDYLQYQLWDTVQAFSSSLSGTLATQASLRGVGVGNQEATVAAATITWLLRDGTGMLGRILFAWLKGSKLDSEAKKWRLFADILNDVAMFIEIAAPHFPPFFTIIVCIAGIFKSIVGVAGGATRAALTVHQARRNNMADISAKDGSQETLVNLAGLLVSLALIPLVTDNPLLTFILFYLFTVLHLFANYKAVRSVVMETLNEARLSIVLHQYLLHGQVLSPAEANQREPVFLSFRRTVPIKLGVRLGDLIHEPGDLQLALKNNSKPYLIGIKNGAVCVCLGSDASVDDEIKAVCQALCVSAVLHNESPLPAVLQQLSNTKDPWALISQSHKMIDEIFQTFLKELDRAKWQTDRTLLDWNEWRVEWTKKRS", "length": 443 }, "evidence": [ { "id": "G3N1G1", "url": "https://omabrowser.org/oma/group/G3N1G1/", "database": "OMA" } ], "glygen_name": "Zebrafish", "common_name": "Zebrafish" }, { "uniprot_canonical_ac": "F1RIS7-1", "protein_name": "RUS family member 1", "gene_name": "RUSF1", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MADVARREAPLCSEQFGSGTARGCRAAADGTLQWEAWGKRWWGFSGAFTAKPGERDGDGGVAPGTASPPLSRLLAVFLPQGFPDSVSPDYLPYQLWDSVQAFASSLSGSLATHAVLLGIGVGNAKASVSAATATWLVKDSTGMLGRIVFAWWMGSKMDCNAKQWRLFADILNDVAMFLEIVAPIFPLCFTVTVCISNLAKCIVGVAGGATRAALTMHQARRNNMADVSAKDGSQETLVGLAGLLVSLLMLPLVSDRPSLSLCCFFFLTALHIYANYRAVRALVIETLNEGRLWLVLKHFLQTQEVLGPTAANRMEPLWTGFWPSLFLSLGAPLHRLTSSVLELQQLVEGHREPYLLRWDQPRNQVQVVLSPMAGPETILRAATHGLLLGALRGDGPLPEELDKLRNRVRAGPEKESWVIVRDMHHVLDKLFPKFLKGLQDAGWRTEKHQLEVDEWRATWLPCPEKKVL", "length": 468 }, "evidence": [ { "id": "G3N1G1", "url": "https://omabrowser.org/oma/group/G3N1G1/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "Q499P8-1", "protein_name": "RUS family member 1", "gene_name": "Rusf1", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MADTASLRAPLCTEQFGSGAPRSCSAAADGSLQWDRAQRWGWFSRASITKPGQHEGGGRGPWAALTTLSGLRSVLLPQGFPDSVSPDYLQYQLWDSVQAFASSLSGSLATQAVLQGLGVGNAKASVSAATSTWLVKDSTGMLGRIIFAWWKGSKLDCNAKQWRLFADILNDTAMFLEIMAPMYPIFFTMTVSTSNLAKCIVGVAGGATRAALTMHQARRNNMADVSAKDSSQETVVNLAGLLVSLLMLPLVSDCLSLSLGCFILLTALHIYANYRAVRALVLETLNESRLQLVLKHFLQRGEVLEPASANQMEPLWTGFWPSLSLSLGVPLHHLVSSVSELKQLVEGHQEPYLLCWNQSQNQVQVALSQVAGPETVLRAATHGLILGALQEDGPLPGELAELRDMVQAGPKNESWILVRETHQVLDTLFPKFLKGLQAAGWKTEKHHLEVDEWRATWPLSPEKKVL", "length": 466 }, "evidence": [ { "id": "G3N1G1", "url": "https://omabrowser.org/oma/group/G3N1G1/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "Q84JB8-1", "protein_name": "Protein root UVB sensitive 3", "gene_name": "RUS3", "tax_id": 3702, "organism": "Arabidopsis thaliana", "sequence": { "sequence": "MREEQVSDCGSITLEEWNGSSSTKLFKTATITASSSLSIQRSANRFNHVWRRVLQAFVPEGFPGSVTPDYVGFQLWDTLQGLSTYTKMMLSTQALLSAIGVGEKSATVIGATFQWFLRDFTGMLGGILFTFYQGSNLDSNAKMWRLVADLMNDIGMLMDLLSPLFPSAFIVVVCLGSLSRSFTGVASGATRAALTQHFALQDNAADISAKEGSQETMATMMGMSLGMLLARFTSGNPMAIWLSFLSLTVFHMYANYRAVRCLVLNSLNFERSSILLTHFIQTGQVLSPEQVSSMEGVLPLWATSLRSTNSKPLHKRVQLGVRVSSLPRLDMLQLLNGVGASSYKNAKYLLAHIKGNVSVILHKDSKPADVLKSYIHAIVLANLMEKSTSFYSEGEAWIDKHYDELLHKLRSGGWKTERLLSPSITWRANWISHTSAAKFD", "length": 440 }, "evidence": [ { "id": "G3N1G1", "url": "https://omabrowser.org/oma/group/G3N1G1/", "database": "OMA" } ], "glygen_name": "Arabidopsis", "common_name": "Mouse-ear cress" }, { "uniprot_canonical_ac": "Q91W34-1", "protein_name": "RUS family member 1", "gene_name": "Rusf1", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MADAASLRAPLCTEQFGSGAPRGCSAAADGSLQWDGARRWGWLSRAPIAKPGQHAGGGGGPWAALTALSGLRSVLLPQGFPDSVSPDYLPYQLWDSVQAFASSLSGSLATQAVLQGLGVGNAKASVSAATSTWLVKDSTGMLGRIILAWWKGSKLDCNAKQWRLFADILNDVAMFLEIMAPMYPIFFTMTVSTSNLAKCIVGVAGGATRAALTMHQARRNNMADVSAKDSSQETVVNLAGLLVSLLMLPLVSDCPSLSLGCFVLLTALHIYANYRAVRALVLETLNESRLQLVLEHFLQRGEVLEPASANQMEPLWTGFWPSLSLSLGVPLHHLVSSVSELKQLVEGHHEPYLLCWNKSRNQVQVALSQEAGPETVLRAATHGLILGALQEDGPLPGELAELRHQVQADPKKESWILVRETHQVLDTLFPKFLKGLQAAGWKTEKHHLEVDEWRATWPLSPEKKVL", "length": 466 }, "evidence": [ { "id": "G3N1G1", "url": "https://omabrowser.org/oma/group/G3N1G1/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q96GQ5-1", "protein_name": "RUS family member 1", "gene_name": "RUSF1", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MADDAGLETPLCSEQFGSGEARGCRAAADGSLQWEVGGWRWWGLSRAFTVKPEGRDAGEVGASGAPSPPLSGLQAVFLPQGFPDSVSPDYLPYQLWDSVQAFASSLSGSLATQAVLLGIGVGNAKATVSAATATWLVKDSTGMLGRIVFAWWKGSKLDCNAKQWRLFADILNDVAMFLEIMAPVYPICFTMTVSTSNLAKCIVSVAGGATRAALTVHQARRNNMADVSAKDSSQETLVNLAGLLVSLLMLPLVSGCPGFSLGCFFFLTALHIYANYRAVRALVMETLNEGRLRLVLKHYLQRGEVLDPTAANRMEPLWTGFWPAPSLSLGVPLHRLVSSVFELQQLVEGHQESYLLCWDQSQNQVQVVLNQKAGPKTILRAATHGLMLGALQGDGPLPAELEELRNRVRAGPKKESWVVVKETHEVLDMLFPKFLKGLQDAGWKTEKHQLEVDEWRATWLLSPEKKVL", "length": 468 }, "evidence": [ { "id": "G3N1G1", "url": "https://omabrowser.org/oma/group/G3N1G1/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" } ], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 1, "go_terms": [ { "name": "membrane", "id": "GO:0016020", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016020", "evidence": [ { "database": "UniProtKB", "id": "G3N1G1", "url": "https://www.uniprot.org/uniprotkb/G3N1G1" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [ { "pdb_id": "AF-G3N1G1-F1", "pdb_chain": "global", "start_pos": 1, "end_pos": 462, "overlap": "1.0", "method": "AlphaFold", "type": "alphafold", "resolution": -1.0, "url": "https://data.glygen.org/ln2downloads/pdb/current/AF-G3N1G1-F1.pdb", "url_external": "https://alphafold.ebi.ac.uk/entry/G3N1G1" } ], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "G3N1G1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3N1G1" }, { "id": "PF04884", "database": "Pfam", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF04884" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "Protein root UVB sensitive/RUS", "eco_id": "ECO_0000259", "start_pos": 63, "end_pos": 296, "start_aa": "Pro", "end_aa": "Arg", "glycosite_overlap": [] }, { "evidence": [ { "id": "G3N1G1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3N1G1" }, { "id": "PF24160", "database": "Pfam", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF24160" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "Root UVB sensitive protein C-terminal", "eco_id": "ECO_0000259", "start_pos": 298, "end_pos": 453, "start_aa": "Glu", "end_aa": "Trp", "glycosite_overlap": [] } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" }, { "name": "homologset.oma", "label": "OMA Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [ 303 ], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 1 }, { "field": "total_sites", "count": 1 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 1 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "exact_sites", "count": 1 }, { "field": "exact_o_linked_sites", "count": 1 }, { "field": "fuzzy_sites", "count": 0 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_pos", "start_aa", "end_pos", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 1 }, { "field": "total_sites", "count": 1 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 1 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "exact_sites", "count": 1 }, { "field": "exact_o_linked_sites", "count": 1 }, { "field": "fuzzy_sites", "count": 0 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_pos", "start_aa", "end_pos", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ], "tool_support": { "graph_view": "yes" } }, { "uniprot_canonical_ac": "G3N2M4-1", "uniprot_ac": "G3N2M4", "uniprot_id": "G3N2M4_BOVIN", "mass": { "chemical_mass": 173208.0, "monoisotopic_mass": 173208.0 }, "refseq": { "ac": "XP_059738724", "name": "PHD and RING finger domain-containing protein 1 isoform X1", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_059738724" }, "gene_names": [ { "name": "PHRF1", "type": "recommended", "evidence": [ { "id": "G3N2M4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3N2M4" } ] }, { "name": "PHRF1", "type": "synonym", "evidence": [ { "id": "XP_059738724", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_059738724" } ] } ], "protein_names": [ { "name": "PHD and RING finger domain-containing protein 1", "type": "recommended", "evidence": [ { "id": "G3N2M4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3N2M4/entry#names_and_taxonomy" } ] }, { "name": "PHD and RING finger domain-containing protein 1 isoform X1", "type": "synonym", "evidence": [ { "id": "XP_059738724", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_059738724" } ] } ], "function": [], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Bos taurus", "taxid": 9913, "evidence": [ { "database": "UniProtKB", "id": "G3N2M4", "url": "https://www.uniprot.org/uniprotkb/G3N2M4" } ], "common_name": "Bovine", "glygen_name": "Bovine", "reference_species": "Bos taurus [9913]" } ], "gene": [ { "name": "PHRF1", "url": "https://www.uniprot.org/uniprotkb/G3N2M4", "locus": { "chromosome": "29", "start_pos": 50699012, "end_pos": 50726834, "strand": "+", "evidence": [ { "database": "Ensembl Gene", "id": "ENSBTAG00000046359", "url": "https://www.ensembl.org/id/ENSBTAG00000046359" } ] } } ], "crossref": [ { "id": "ENSBTAG00000046359", "url": "https://bgee.org/?page=gene&gene_id=ENSBTAG00000046359", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "cd15536", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd15536", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "cd16635", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd16635", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "100126170", "url": "https://www.ncbi.nlm.nih.gov/gene/100126170", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR001841", "url": "https://www.ebi.ac.uk/interpro/entry/IPR001841", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR001965", "url": "https://www.ebi.ac.uk/interpro/entry/IPR001965", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR011011", "url": "https://www.ebi.ac.uk/interpro/entry/IPR011011", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR013083", "url": "https://www.ebi.ac.uk/interpro/entry/IPR013083", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR017907", "url": "https://www.ebi.ac.uk/interpro/entry/IPR017907", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR019787", "url": "https://www.ebi.ac.uk/interpro/entry/IPR019787", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR047157", "url": "https://www.ebi.ac.uk/interpro/entry/IPR047157", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR057031", "url": "https://www.ebi.ac.uk/interpro/entry/IPR057031", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "G3N2M4", "url": "https://www.orthodb.org/?gene=G3N2M4", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR12618", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR12618", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR12618:SF20", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR12618:SF20", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00628", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00628", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF13639", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF13639", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF23030", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF23030", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "XP_059738724", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_059738724", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0AAA9TIG1", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TIG1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0AAA9TIG1-1", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TIG1-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "G3N2M4", "url": "https://www.uniprot.org/uniprotkb/G3N2M4", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "G3N2M4-1", "url": "https://www.uniprot.org/uniprotkb/G3N2M4-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MDDDSLDELVDRSPGPDGHPRLRPAALASDAEGSSDAHSDASEDDSGSEHSDEEDADGDLEDGSGSEDSEDDGDDLDALAAAADSQGALEGSGAFNSDDDSESCPICLNAFREQAVGTPENCAHYFCLDCIVEWSKNANSCPVDRTIFKCICIRAQFGGKILKKIPVESAHLGENENEDPTFCEVCGRSDREDRLLLCDGCDAGYHMECLDPPLQEVPVDEWFCPECATPGAASAADAGPVSEEEVSLLLADVVPTTSRLRPRTGRTRAIARTRQSERVRATVNRNRISTARRFQRVPRYLMSSLLDETIEAVAAGLSTAVYQRPGPRAPARRRRKGGRRKKTSGRKKAPSRLSAKSRSSGARLKKRPGRVKKRKAQKIKNEATARSRIARTLGLCRPACGACTPSVYKPADPSLGLMRADIGAASLSLFGDPYELDPFDSSEEASASPASPLSAKRRVLSRSALRSHQPVARPISMGLSRRGAPAVAPQPEVDTEPSPDLLGSILSGQSLLMMNGADIIIHRDGSLSAKRAVPVSFQQNSAGPSREPEGAWGRQSGSGPQSSGPSCPGRAAPAPTRVPALTSGAAAKPDSSVTPRLGQSQTSSSESRPGIQQSEGGQCNGDSKHSLPLGPAALKASHSSSDSPSKSTVPGQAPRPAPRRTDISELPRIPKIRRDSSRGDEGPASRQGVELPSSCISRLTGREGPGQPGCGARVEGEPSNRGAQEPSTHSGGGPQPPGPLGPARGKAVGSTFESFRINIPGNTAHSGRLLSPGFCNTFRPVDSKVQRRASPSPLFSVRKTKQLKSEIYDPFNPTGSDSSSANSSPERLGLLPSEITRTISVDSPKAPVLPPVRCVTSYTVQTGAGRELEPPQGPSSLPELQDEEPCAQAQRPSPPEPWGDEELPPHSSFFGSEGRTVTCVTVVEPDTPPSPDAPPATTHRVVELRSLSRSRSRSSSRSRKKGPQPRAATREHRAGRSGSRSSRSGDRSSRSASPPAGEDQPKGHRPKARGRRSSSEHSSSRERAKRKKAKDKSRERGRGSWGRGRRRSRSRSGSPGSSSHEHREGRRKKRRRSGSRSRGRECSPPRHPRERRGRPRDRRGSRERRRRRSRSPSSEHRPRAHRRPRSREKRSRPRPHSPERKLAPKEASAAPAPQGEPRPDREPPARSPARPPSSAGADGLPEGPEVHKTAPVPEVLAACPAEDVDYGDSVEAGHLFEDFSSDTIFMQLDDMSSPPSPESTDSSPERDLLPKTTMPPAGPQHDTSLAMAIIRREVSRIHGEDVAQPSPGTEGPQEKHLLQQDADEAAAVPCALGAQAPGGMPVGKEEGPSQNPLLRAKALVKRVTWNLQEAECGAPANDRGLSRRQSCGLEGPRTPTPICWPPGTPLHRPQKPREGVWESDDVGPMAGFQQAPFSEPPAPAYALPEPGFPYTDPSQVQSPSLPPGPALPSGIPPYAPISQPAVQFLLQGSLPLPGCGAAQSMAPVSTTPTAASEPAGHAAATTAANNSEERTAPPRPTPEKAKNEEYMKKLHVQERAVEEVKLAIKPFYQKREVTKEEYKDILRKAVQKICHSKSGEINPVKVGNLVKAYVDKYRHMRRHRRAEAGEEPPAQSAEG", "length": 1615, "header": "tr|G3N2M4-1|G3N2M4_BOVIN Isoform 1 of PHD and RING finger domain-containing protein 1 OS=Bos taurus OX=9913 GN=PHRF1 PE=4 SV=2 CANONICAL=G3N2M4-1" }, "isoforms": [ { "isoform_ac": "A0AAA9TIG1-1", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TIG1/entry", "sequence": { "sequence": "MLTACRSVRCAYQRGRRYISRCRAERPCPAMDDDSLDELVDRSPGPDGHPRLRPAALASDAEGSSDAHSDASEDDSGSEHSDEEDADGDLEDGSGSEDSEDDGDDLDALAAAADSQGALEGSGAFNSDDDSESCPICLNAFREQAVGTPENCAHYFCLDCIVEWSKNANSCPVDRTIFKCICIRAQFGGKILKKIPVESAHLGENENEDPTFCEVCGRSDREDRLLLCDGCDAGYHMECLDPPLQEVPVDEWFCPECATPGAASAADAGPVSEEEVSLLLADVVPTTSRLRPRTGRTRAIARTRQSERVRATVNRNRISTARRFQRVPRYLMSSLLDETIEAVAAGLSTAVYQRPGPRAPARRRRKGGRRKKTSGRKKAPSRLSAKSRSSGARLKKRPGRVKKRKAQKIKNEATARSRIARTLGLCRPACGACTPSVYKPADPSLGLMRADIGAASLSLFGDPYELDPFDSSEEASASPASPLSAKRRVLSRSALRSHQPVARPISMGLSRRGAPAVAPQPEVDTEPSPDLLGSILSGQSLLMMNGADIIIHRDGSLSAKRAVPVSFQQNSAGPSREPEGAWGRQSGSGPQSSGPSCPGRAAPAPTRVPALTSGAAAKPDSSVTPRLGQSQTSSSESRPGIQQSEGGQCNGDSKHSLPLGPAALKASHSSSDSPSKSTVPGQAPRPAPRRTDISELPRIPKIRRDSSRGDEGPASRQGVELPSSCISRLTGREGPGQPGCGARVEGEPSNRGAQEPSTHSGGGPQPPGPLGPARGKAVGSTFESFRINIPGNTAHSGRLLSPGFCNTFRPVDSKVQRRASPSPLFSVRKTKQLKSEIYDPFNPTGSDSSSANSSPERLGLLPSEITRTISVDSPKAPVLPPVRCVTSYTVQTGAGRELEPPQGPSSLPELQDEEPCAQAQRPSPPEPWGDEELPPHSSFFGSEGRTVTCVTVVEPDTPPSPDAPPATTHRVVELRSLSRSRSRSSSRSRKKGPQPRAATREHRAGRSGSRSSRSGDRSSRSASPPAGEDQPKGHRPKARGRRSSSEHSSSRERAKRKKAKDKSRERGRGSWGRGRRRSRSRSGSPGSSSHEHREGRRKKRRRSGSRSRGRECSPPRHPRERRGRPRDRRGSRERRRRRSRSPSSEHRPRAHRRPRSREKRSRPRPHSPERKLAPKEASAAPAPQGEPRPDREPPARSPARPPSSAGADGLPEGPEVHKTAPVPEVLAACPAEDVDYGDSVEAGHLFEDFSSDTIFMQLDDMSSPPSPESTDSSPERDLLPKTTMPPAGPQHDTSLAMAIIRREVSRIHGEDVAQPSPGTEGPQEKHLLQQDADEAAAVPCALGAQAPGGMPVGKEEGPSQNPLLRAKALVKRVTWNLQEAECGAPANDRGLWTPLHRPQKPREGVWESDDVGPMAGFQQAPFSEPPAPAYALPEPGFPYTDPSQVQSPSLPPGPALPSGIPPYAPISQPAVQFLLQGSLPLPGCGAAQSMAPVSTTPTAASEPAGHAAATTAANNSEERTAPPRPTPEKAKNEEYMKKLHVQERAVEEVKLAIKPFYQKREVTKEEYKDILRKAVQKICHSKSGEINPVKVGNLVKAYVDKYRHMRRHRRAEAGEEPPAQSAEG", "length": 1624, "header": "tr|A0AAA9TIG1-1|G3N2M4_BOVIN Computationally mapped isoform of PHD and RING finger domain-containing protein 1 OS=Bos taurus OX=9913 GN=PHRF1 PE=4 SV=1 CANONICAL=G3N2M4-1" }, "locus": { "chromosome": "29", "start_pos": 50726749, "end_pos": 50699202, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000125154.1", "url": "https://www.ensembl.org/id/ENSBTAT00000125154.1" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000098258.1", "url": "https://www.ensembl.org/id/ENSBTAP00000098258.1" } ] } }, { "isoform_ac": "G3N2M4-1", "url": "https://www.uniprot.org/uniprotkb/G3N2M4/entry", "sequence": { "sequence": "MDDDSLDELVDRSPGPDGHPRLRPAALASDAEGSSDAHSDASEDDSGSEHSDEEDADGDLEDGSGSEDSEDDGDDLDALAAAADSQGALEGSGAFNSDDDSESCPICLNAFREQAVGTPENCAHYFCLDCIVEWSKNANSCPVDRTIFKCICIRAQFGGKILKKIPVESAHLGENENEDPTFCEVCGRSDREDRLLLCDGCDAGYHMECLDPPLQEVPVDEWFCPECATPGAASAADAGPVSEEEVSLLLADVVPTTSRLRPRTGRTRAIARTRQSERVRATVNRNRISTARRFQRVPRYLMSSLLDETIEAVAAGLSTAVYQRPGPRAPARRRRKGGRRKKTSGRKKAPSRLSAKSRSSGARLKKRPGRVKKRKAQKIKNEATARSRIARTLGLCRPACGACTPSVYKPADPSLGLMRADIGAASLSLFGDPYELDPFDSSEEASASPASPLSAKRRVLSRSALRSHQPVARPISMGLSRRGAPAVAPQPEVDTEPSPDLLGSILSGQSLLMMNGADIIIHRDGSLSAKRAVPVSFQQNSAGPSREPEGAWGRQSGSGPQSSGPSCPGRAAPAPTRVPALTSGAAAKPDSSVTPRLGQSQTSSSESRPGIQQSEGGQCNGDSKHSLPLGPAALKASHSSSDSPSKSTVPGQAPRPAPRRTDISELPRIPKIRRDSSRGDEGPASRQGVELPSSCISRLTGREGPGQPGCGARVEGEPSNRGAQEPSTHSGGGPQPPGPLGPARGKAVGSTFESFRINIPGNTAHSGRLLSPGFCNTFRPVDSKVQRRASPSPLFSVRKTKQLKSEIYDPFNPTGSDSSSANSSPERLGLLPSEITRTISVDSPKAPVLPPVRCVTSYTVQTGAGRELEPPQGPSSLPELQDEEPCAQAQRPSPPEPWGDEELPPHSSFFGSEGRTVTCVTVVEPDTPPSPDAPPATTHRVVELRSLSRSRSRSSSRSRKKGPQPRAATREHRAGRSGSRSSRSGDRSSRSASPPAGEDQPKGHRPKARGRRSSSEHSSSRERAKRKKAKDKSRERGRGSWGRGRRRSRSRSGSPGSSSHEHREGRRKKRRRSGSRSRGRECSPPRHPRERRGRPRDRRGSRERRRRRSRSPSSEHRPRAHRRPRSREKRSRPRPHSPERKLAPKEASAAPAPQGEPRPDREPPARSPARPPSSAGADGLPEGPEVHKTAPVPEVLAACPAEDVDYGDSVEAGHLFEDFSSDTIFMQLDDMSSPPSPESTDSSPERDLLPKTTMPPAGPQHDTSLAMAIIRREVSRIHGEDVAQPSPGTEGPQEKHLLQQDADEAAAVPCALGAQAPGGMPVGKEEGPSQNPLLRAKALVKRVTWNLQEAECGAPANDRGLSRRQSCGLEGPRTPTPICWPPGTPLHRPQKPREGVWESDDVGPMAGFQQAPFSEPPAPAYALPEPGFPYTDPSQVQSPSLPPGPALPSGIPPYAPISQPAVQFLLQGSLPLPGCGAAQSMAPVSTTPTAASEPAGHAAATTAANNSEERTAPPRPTPEKAKNEEYMKKLHVQERAVEEVKLAIKPFYQKREVTKEEYKDILRKAVQKICHSKSGEINPVKVGNLVKAYVDKYRHMRRHRRAEAGEEPPAQSAEG", 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"", "database": "GlyGen", "url": "https://data.glygen.org/" } ], "filter_code": "000000000000000010000.00000000001000.0.01000" }, { "glytoucan_ac": "", "type": "O-linked", "subtype": "other", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 229, "start_aa": "Thr", "end_pos": 229, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr229", "evidence": [ { "id": "", "database": "GlyGen", "url": "https://data.glygen.org/" } ], "filter_code": "000000000000000010000.00000000001000.0.01000" } ], "phosphorylation": [], "glycation": [], "keywords": [ "glycoprotein", "glycoprotein_predicted" ], "publication": [], "pathway": [], "orthologs": [], "go_annotation": { "categories": [ { "name": "Molecular Function", "total": 1, "go_terms": [ { "name": "zinc ion binding", "id": "GO:0008270", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008270", "evidence": [ { "database": "UniProtKB", "id": "G3N2M4", "url": "https://www.uniprot.org/uniprotkb/G3N2M4" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 1505, "end_pos": 1507, "annotation": "n_glycosylation_sequon" }, { "start_pos": 822, "end_pos": 824, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "G3N2M4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3N2M4" }, { "id": "PS50016", "database": "PROSITE", "url": "https://prosite.expasy.org/PS50016" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "PHD-type", "eco_id": "ECO_0000259", "start_pos": 180, "end_pos": 230, "start_aa": "Pro", "end_aa": "Pro", "glycosite_overlap": [] }, { "evidence": [ { "id": 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"o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ], "tool_support": { "graph_view": "yes" } }, { "uniprot_canonical_ac": "G3MXL8-1", "uniprot_ac": "G3MXL8", "uniprot_id": "G3MXL8_BOVIN", "mass": { "chemical_mass": 60295.0, "monoisotopic_mass": 60295.0 }, "refseq": {}, "gene_names": [ { "name": "CERK", "type": "recommended", "evidence": [ { "id": "G3MXL8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3MXL8" } ] } ], "protein_names": [ { "name": "Ceramide kinase", "type": "recommended", "evidence": [ { "id": "G3MXL8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3MXL8/entry#names_and_taxonomy" } ] }, { "name": "2.7.1.138", "type": "synonym", "evidence": [ { "id": "G3MXL8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3MXL8/entry#names_and_taxonomy" } ] }, { "name": "Acylsphingosine kinase", "type": "synonym", "evidence": [ { "id": "G3MXL8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3MXL8/entry#names_and_taxonomy" } ] } ], "function": [ { "annotation": "Catalyzes specifically the phosphorylation of ceramide to form ceramide 1-phosphate. Acts efficiently on natural and analog ceramides (C6, C8, C16 ceramides, and C8-dihydroceramide), to a lesser extent on C2-ceramide and C6-dihydroceramide, but not on other lipids, such as various sphingosines. Shows a greater preference for D-erythro isomer of ceramides. Binds phosphoinositides.", "evidence": [ { "database": "UniProtKB", "id": "A0AAA9TMR3", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TMR3#function" }, { "database": "UniProtKB", "id": "ARBA00055034", "url": "https://www.uniprot.org/uniprotkb/ARBA00055034#function" }, { "database": "UniProtKB", "id": "G3MXL8", "url": "https://www.uniprot.org/uniprotkb/G3MXL8#function" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Bos taurus", "taxid": 9913, "evidence": [ { "database": "UniProtKB", "id": "G3MXL8", "url": "https://www.uniprot.org/uniprotkb/G3MXL8" } ], "common_name": "Bovine", "glygen_name": "Bovine", "reference_species": "Bos taurus [9913]" } ], "gene": [ { "name": "CERK", "url": "https://www.uniprot.org/uniprotkb/G3MXL8", "locus": { "chromosome": "5", "start_pos": 116907659, "end_pos": 116943349, "strand": "+", "evidence": [ { "database": "Ensembl Gene", "id": "ENSBTAG00000046654", "url": "https://www.ensembl.org/id/ENSBTAG00000046654" } ] } } ], "crossref": [ { "id": "G3MXL8", "url": "https://alphafold.ebi.ac.uk/entry/G3MXL8", "database": "AlphaFoldDB", "categories": [] }, { "id": "ENSBTAG00000046654", "url": "https://bgee.org/?page=gene&gene_id=ENSBTAG00000046654", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "IPR001206", "url": "https://www.ebi.ac.uk/interpro/entry/IPR001206", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR016064", "url": "https://www.ebi.ac.uk/interpro/entry/IPR016064", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR017438", "url": "https://www.ebi.ac.uk/interpro/entry/IPR017438", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR045363", "url": "https://www.ebi.ac.uk/interpro/entry/IPR045363", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR050187", "url": "https://www.ebi.ac.uk/interpro/entry/IPR050187", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR057465", "url": "https://www.ebi.ac.uk/interpro/entry/IPR057465", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "PTHR12358", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR12358", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR12358:SF25", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR12358:SF25", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00781", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00781", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF19280", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF19280", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF25382", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF25382", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "R-BTA-9840309", "url": "https://www.reactome.org/PathwayBrowser/#R-BTA-9840309", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "17929", "url": "https://www.rhea-db.org/rhea/17929", "database": "Rhea", "categories": [ "Enzyme and Pathway" ] }, { "id": "43312", "url": "https://www.rhea-db.org/rhea/43312", "database": "Rhea", "categories": [ "Enzyme and Pathway" ] }, { "id": "46340", "url": "https://www.rhea-db.org/rhea/46340", "database": "Rhea", "categories": [ "Enzyme and Pathway" ] }, { "id": "47904", "url": "https://www.rhea-db.org/rhea/47904", "database": "Rhea", "categories": [ "Enzyme and Pathway" ] }, { "id": "47916", "url": "https://www.rhea-db.org/rhea/47916", "database": "Rhea", "categories": [ "Enzyme and Pathway" ] }, { "id": "A0AAA9TMR3", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TMR3", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0AAA9TMR3-1", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TMR3-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "G3MXL8", "url": "https://www.uniprot.org/uniprotkb/G3MXL8", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "G3MXL8-1", "url": "https://www.uniprot.org/uniprotkb/G3MXL8-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "PGAMGAAEPLRSVLWVKQQRCAVSLDPARALLRWWRSPGPGAGDPGADACTVPISEIITVEETDVNGKQYSSGKWQKMEKPYAFTVHRVRRARRHRWRWAQVTFWCPEEQLYHLWLQTLRELLETLTSRPKHLLVFINPLGGRGQGKRIYEKKVAPLFTLASITTEIIVTERANHAKESLYELNIDKYDGIVCVGGDGMFSEVLHGLVGRTQRDAGVDQNQPRATLVPSPLRIGIIPAGSTDCVCYSTVGTNDAETSALHIIVGDSLSMDVSAVHHDSTLLRYSVSLLGYGFYGDIIKDSERKRWMGLIRYDFSGLKTFFSHHCYEGTVSFLPAQHTVGSPRDRKPCRAGCPVCRQSRQQLEEEQKRSLYGLDGTEEVEEWKVLCGQFLAINATNMSCACPRSPQGLSPAAHLGDGSSDLILIRKCSRFNFLRFLVRHTNQGDQFDFTFVEVYRVKKFQFVSKPAEEEDSSVLGRGKKRLGPLCSEHPTSCCCRSSRSSWNCDGEVLSSPAIEVRVHCQLVRLFARGIEESPKQESRG", "length": 538, "header": "tr|G3MXL8-1|G3MXL8_BOVIN Isoform 1 of Ceramide kinase OS=Bos taurus OX=9913 GN=CERK PE=4 SV=3 CANONICAL=G3MXL8-1" }, "isoforms": [ { "isoform_ac": "A0AAA9TMR3-1", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TMR3/entry", "sequence": { "sequence": "MAGLPTWLSGKESGCQCQRLRFNPWSGKIAQATEQLRMCTTAAEPVLRGAGAATAELTLCGSRSPCSAAGEASALRDPPPAAGGKPLLQQGPSTARDQINACTVPISEIITVEETDVNGKQYSSGKWQKMEKPYAFTVHRVRRARRHRWRWAQVTFWCPEEQLYHLWLQTLRELLETLTSRPKHLLVFINPLGGRGQGKRIYEKKVAPLFTLASITTEIIVTERANHAKESLYELNIDKYDGIVCVGGDGMFSEVLHGLVGRTQRDAGVDQNQPRATLVPSPLRIGIIPAGSTDCVCYSTVGTNDAETSALHIIVGDSLSMDVSAVHHDSTLLRYSVSLLGYGFYGDIIKDSERKRWMGLIRYDFSGLKTFFSHHCYEGTVSFLPAQHTVGSPRDRKPCRAGCPVCRQSRQQLEEEQKRSLYGLDGTEEVEEWKVLCGQFLAINATNMSCACPRSPQGLSPAAHLGDGSSDLILIRKCSRFNFLRFLVRHTNQGDQFDFTFVEVYRVKKFQFVSKPAEEEDSSVLGRGKKRLGPLCSEHPTSCCCRSSRSSWNCDGEVLSSPAIEVRVHCQLVRLFARGIEESPKQESRG", "length": 590, "header": "tr|A0AAA9TMR3-1|G3MXL8_BOVIN Computationally mapped isoform of Ceramide kinase OS=Bos taurus OX=9913 GN=CERK PE=4 SV=1 CANONICAL=G3MXL8-1" }, "locus": { "chromosome": "5", "start_pos": 116937460, "end_pos": 116908663, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000120380.1", "url": "https://www.ensembl.org/id/ENSBTAT00000120380.1" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000099794.1", "url": "https://www.ensembl.org/id/ENSBTAP00000099794.1" } ] } }, { "isoform_ac": "G3MXL8-1", "url": "https://www.uniprot.org/uniprotkb/G3MXL8/entry", "sequence": { "sequence": "PGAMGAAEPLRSVLWVKQQRCAVSLDPARALLRWWRSPGPGAGDPGADACTVPISEIITVEETDVNGKQYSSGKWQKMEKPYAFTVHRVRRARRHRWRWAQVTFWCPEEQLYHLWLQTLRELLETLTSRPKHLLVFINPLGGRGQGKRIYEKKVAPLFTLASITTEIIVTERANHAKESLYELNIDKYDGIVCVGGDGMFSEVLHGLVGRTQRDAGVDQNQPRATLVPSPLRIGIIPAGSTDCVCYSTVGTNDAETSALHIIVGDSLSMDVSAVHHDSTLLRYSVSLLGYGFYGDIIKDSERKRWMGLIRYDFSGLKTFFSHHCYEGTVSFLPAQHTVGSPRDRKPCRAGCPVCRQSRQQLEEEQKRSLYGLDGTEEVEEWKVLCGQFLAINATNMSCACPRSPQGLSPAAHLGDGSSDLILIRKCSRFNFLRFLVRHTNQGDQFDFTFVEVYRVKKFQFVSKPAEEEDSSVLGRGKKRLGPLCSEHPTSCCCRSSRSSWNCDGEVLSSPAIEVRVHCQLVRLFARGIEESPKQESRG", "length": 538, "header": "tr|G3MXL8-1|G3MXL8_BOVIN Isoform 1 of Ceramide kinase OS=Bos taurus OX=9913 GN=CERK PE=4 SV=3 CANONICAL=G3MXL8-1" }, "locus": { "chromosome": "5", "start_pos": 116943150, "end_pos": 116908663, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000064397.3", "url": "https://www.ensembl.org/id/ENSBTAT00000064397.3" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000054285.3", "url": "https://www.ensembl.org/id/ENSBTAP00000054285.3" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [ "enzyme" ], "publication": [], "pathway": [ { "id": "R-BTA-9840309", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-BTA-9840309", "resource": "Reactome", "description": "Glycosphingolipid biosynthesis" } ], "orthologs": [], "go_annotation": { "categories": [ { "name": "Molecular Function", "total": 3, "go_terms": [ { "name": "magnesium ion binding", "id": "GO:0000287", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000287", "evidence": [ { "database": "UniProtKB", "id": "G3MXL8", "url": "https://www.uniprot.org/uniprotkb/G3MXL8" } ], "pmid": "" }, { "name": "ceramide kinase activity", "id": "GO:0001729", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0001729", "evidence": [ { "database": "UniProtKB", "id": "G3MXL8", "url": "https://www.uniprot.org/uniprotkb/G3MXL8" } ], "pmid": "" }, { "name": "ATP binding", "id": "GO:0005524", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005524", "evidence": [ { "database": "UniProtKB", "id": "G3MXL8", "url": "https://www.uniprot.org/uniprotkb/G3MXL8" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 3, "go_terms": [ { "name": "plasma membrane", "id": "GO:0005886", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005886", "evidence": [ { "database": "UniProtKB", "id": "G3MXL8", "url": "https://www.uniprot.org/uniprotkb/G3MXL8" } ], "pmid": "" }, { "name": "cytoplasmic side of trans-Golgi network membrane", "id": "GO:0160281", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0160281", "evidence": [ { "database": "UniProtKB", "id": "G3MXL8", "url": "https://www.uniprot.org/uniprotkb/G3MXL8" } ], "pmid": "" }, { "name": "cytoplasm", "id": "GO:0005737", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005737", "evidence": [ { "database": "UniProtKB", "id": "G3MXL8", "url": "https://www.uniprot.org/uniprotkb/G3MXL8" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 1, "go_terms": [ { "name": "ceramide metabolic process", "id": "GO:0006672", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006672", "evidence": [ { "database": "UniProtKB", "id": "G3MXL8", "url": "https://www.uniprot.org/uniprotkb/G3MXL8" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 392, "end_pos": 394, "annotation": "n_glycosylation_sequon" }, { "start_pos": 395, "end_pos": 397, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [ { "id": "17929", "name": "", "equation": "an N-acylsphing-4-enine + ATP = an N-acylsphing-4-enine 1-phosphate + ADP + H(+)", "summary": "", "cellular_location": "", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [ "G3MXL8-1" ], "evidence": [ { "id": "17929", "database": "Rhea", "url": "https://www.rhea-db.org/rhea/17929" } ] }, { "id": "43312", "name": "", "equation": "N-(hexanoyl)sphing-4-enine + ATP = N-hexanoylsphing-4-enine 1-phosphate + ADP + H(+)", "summary": "", "cellular_location": "", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [ "G3MXL8-1" ], "evidence": [ { "id": "43312", "database": "Rhea", "url": "https://www.rhea-db.org/rhea/43312" } ] }, { "id": "46340", "name": "", "equation": "N-hexadecanoylsphing-4-enine + ATP = N-(hexadecanoyl)-sphing-4-enine-1-phosphate + ADP + H(+)", "summary": "", "cellular_location": "", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [ "G3MXL8-1" ], "evidence": [ { "id": "46340", "database": "Rhea", "url": "https://www.rhea-db.org/rhea/46340" } ] }, { "id": "47904", "name": "", "equation": "N-(acetyl)-sphing-4-enine + ATP = N-(acetyl)-sphing-4-enine-1-phosphate + ADP + H(+)", "summary": "", "cellular_location": "", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [ "G3MXL8-1" ], "evidence": [ { "id": "47904", "database": "Rhea", "url": "https://www.rhea-db.org/rhea/47904" } ] }, { "id": "47916", "name": "", "equation": "N-hexanoyl-(4R)-hydroxysphinganine + ATP = N-hexanoyl-(4R)-hydroxysphinganine-1-phosphate + ADP + H(+)", "summary": "", "cellular_location": "", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [ "G3MXL8-1" ], "evidence": [ { "id": "47916", "database": "Rhea", "url": "https://www.rhea-db.org/rhea/47916" } ] }, { "id": "R-BTA-1638845", "name": "CERK phosphorylates CERA to form C1P", "equation": "", "summary": "This event has been computationally inferred from an event that has been demonstrated in another species.

The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.

More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "cellular_location": "cytosol, plasma membrane", "input_participant_list": [ "R-ALL-429807" ], "output_participant_list": [ "R-ALL-1638840" ], "enzyme_list": [ "G3MXL8-1" ], "evidence": [ { "id": "R-BTA-1638845", "database": "Reactome", "url": "https://www.reactome.org/PathwayBrowser/#R-BTA-1638845" } ] } ], "reaction_participants": [ { "participant_id": "R-ALL-1638840", "participant_name": "C1P [plasma membrane]", "crossref": [ { "id": "16197", "database": "ChEBI", "url": "" }, { "id": "C02960", "database": "COMPOUND", "url": "" } ] }, { "participant_id": "R-ALL-429807", "participant_name": "CERA [plasma membrane]", "crossref": [ { "id": "83273", "database": "ChEBI", "url": "" } ] } ], "reaction_enzymes": [ { "uniprot_ac": "G3MXL8", "gene_name": "CERK", "activity": [ { "ec_number": "2.7.1.138", "activity": "an N-acylsphing-4-enine + ATP = an N-acylsphing-4-enine 1-phosphate + ADP + H(+).", "evidence": [ { "id": 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"https://www.ebi.ac.uk/interpro/entry/pfam/PF12400", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "A0AAA9TQZ0", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TQZ0", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0AAA9TQZ0-1", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TQZ0-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "F6RY84", "url": "https://www.uniprot.org/uniprotkb/F6RY84", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "F6RY84-1", "url": "https://www.uniprot.org/uniprotkb/F6RY84-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MQGPAGNSSHSLTGGPPSTVASGAGRCESGALMHSFGIFLQGLLGVVAFSTLMLKRFREPKHERRPWRIWFLDTSKQAIGMLFIHFANVYLADLNEEDPCSLYLINFLLDATVGMLLIYVGVRAVSVLVEWQQWESLRFGEYGDPLQCGAWVGQCALYIVIMIFEKSVVFIVLLILQWKKVALLNPIENPDLKLAIVMLIVPFFVNALMFWVVDNFLMRKGRTKAKLEERGANQDSRNGSKVRYRRAASHEESESEILISADDEMEESDVEEDLRRLTPLKPAKKKKHRFGLPV", "length": 294, "header": "tr|F6RY84-1|F6RY84_BOVIN Isoform 1 of STIM activating enhancer OS=Bos taurus OX=9913 GN=STIMATE PE=4 SV=1 CANONICAL=F6RY84-1" }, "isoforms": [ { "isoform_ac": "A0AAA9TQZ0-1", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TQZ0/entry", "sequence": { "sequence": "MQGPAGNSSHSLTGGPPSTVASGAGRCESGALMHSFGIFLQGLLGVVAFSTLMLKRFREPKHERRPWRIWFLDTSKQAIGMLFIHFANVYLADLNEEDPCSLYLINFLLDATVGMLLIYVGVRAVSVLVEWQQWESLRFGEYGDPLQCGAWVGQCALYIVIMIFEKSVVFIVLLILQWKKIKPWTYVKPMKIQSLPCSCLRHQVALLNPIENPDLKLAIVMLIVPFFVNALMFWVVDNFLMRKGRTKAKLEERGANQDSRNGSKVRYRRAASHEESESEILISADDEMEESDVEEDLRRLTPLKPAKKKKHRFGLPV", "length": 317, "header": "tr|A0AAA9TQZ0-1|F6RY84_BOVIN Computationally mapped isoform of STIM activating enhancer OS=Bos taurus OX=9913 GN=STIMATE PE=4 SV=1 CANONICAL=F6RY84-1" }, "locus": { "chromosome": "22", "start_pos": 48050778, "end_pos": 48000397, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000132534.2", "url": "https://www.ensembl.org/id/ENSBTAT00000132534.2" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000100781.1", "url": "https://www.ensembl.org/id/ENSBTAP00000100781.1" } ] } }, { "isoform_ac": "F6RY84-1", "url": "https://www.uniprot.org/uniprotkb/F6RY84/entry", "sequence": { "sequence": "MQGPAGNSSHSLTGGPPSTVASGAGRCESGALMHSFGIFLQGLLGVVAFSTLMLKRFREPKHERRPWRIWFLDTSKQAIGMLFIHFANVYLADLNEEDPCSLYLINFLLDATVGMLLIYVGVRAVSVLVEWQQWESLRFGEYGDPLQCGAWVGQCALYIVIMIFEKSVVFIVLLILQWKKVALLNPIENPDLKLAIVMLIVPFFVNALMFWVVDNFLMRKGRTKAKLEERGANQDSRNGSKVRYRRAASHEESESEILISADDEMEESDVEEDLRRLTPLKPAKKKKHRFGLPV", "length": 294, "header": "tr|F6RY84-1|F6RY84_BOVIN Isoform 1 of STIM activating enhancer OS=Bos taurus OX=9913 GN=STIMATE PE=4 SV=1 CANONICAL=F6RY84-1" }, "locus": { "chromosome": "22", "start_pos": 48050778, "end_pos": 48000397, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000015075.7", "url": "https://www.ensembl.org/id/ENSBTAT00000015075.7" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000015075.5", "url": "https://www.ensembl.org/id/ENSBTAP00000015075.5" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [], "orthologs": [ { "uniprot_canonical_ac": "A0A4X1VHF7-1", "protein_name": "STIM activating enhancer", "gene_name": "STIMATE", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MQGPAGNTSRALPGGPPSTVASGAGRCESGALMHSFGIFLQGLLGVVAFSTLLLKRFREPKHERRPWRIWFLDTSKQAIGMLFIHFANVYLADLTEEDPCSLYLINFLLDATVGMLLIYVGVRAVSVLVEWQQWESLRFGEYGDPLQCGAWVGQCALYIVIMIFEKSVVFIVLLILQWKKVALLNPIENPDLKLAIVMLIVPFFVNALMFWVVDNFLMRKGRTKAKLEERGANQDSRNGSKVRYRRAASHEESESEILISADDEMEESDVEEDLRRLTPLKPAKKKKHRFGLPV", "length": 294 }, "evidence": [ { "id": "F6RY84", "url": "https://omabrowser.org/oma/group/F6RY84/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "F1NIC7-1", "protein_name": "STIM activating enhancer", "gene_name": "LOC121106612", "tax_id": 9031, "organism": "Gallus gallus", "sequence": { "sequence": "MGVTPPNCSLGAALSPQPGAGPAAGPGERGCENGALMDSFGIFLQGLLGVLAFSILMLKRLREPKHERRPWRIWFLDTSKQAIGMLFIHFANVYLSDLTEEDPCSLYFINFLLDATLGMLLIYAGIRAVSSIVEWQQWESLRFGEYGDPLQCSAWMGQCALYIMIMTFEKTIIIIVLLIPQWKEVALLNPIENPQLELAIVMLIVPFFVNAFIFWVVDNFLMKKGKTKAKLEEKEAGQDSRNGSKVRYRRAASHEESESEILISADDEMEESDVEEDLRRLTNLKPIKKKKHRFGLPV", "length": 298 }, "evidence": [ { "id": "F6RY84", "url": "https://omabrowser.org/oma/group/F6RY84/", "database": "OMA" } ], "glygen_name": "Chicken", "common_name": "Chicken" }, { "uniprot_canonical_ac": "Q12042-1", "protein_name": "Vacuolar membrane protein YPL162C", "gene_name": "", "tax_id": 559292, "organism": "Saccharomyces cerevisiae S288C", "sequence": { "sequence": "MYVSNGKDTCQLLGPVSLFVQTLMGMTAVIVLLVKRNYEHPRRKMIVWSYDIGKQIIGSLGIHFLNLGISILKKRRRSLFAITAKGNDDEDQCDWYFLNLLLDTTVGIPILWLCLYIIEKVLKSLHFQNIESGNYFPSKTVGSHPRKPLFSAFVKQLLIFIVGLGVMKFCVFLILNYLEDLAYWFADLILGWSDSWPNFQVFLVMFVFPILLNCFQYFCVDNVIRLHSESLTITNAENFETNTFLNDEIPDLSEVSNEVPNKDNNISSYGSII", "length": 273 }, "evidence": [ { "id": "F6RY84", "url": "https://omabrowser.org/oma/group/F6RY84/", "database": "OMA" } ], "glygen_name": "Yeast", "common_name": "Baker's yeast" }, { "uniprot_canonical_ac": "Q3UF25-1", "protein_name": "Store-operated calcium entry regulator STIMATE", "gene_name": "Stimate", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MQGPGGNVSRGLPSGPASTVASGAGRCESGALMHSFGIFLQGLLGVVAFSTLMLKRFREPKHERRPWRIWFLDTSKQAIGMLFIHFANVYLADLTEEDPCSLYLINFLLDATVGMLLIYVGVRAVGVLVEWQQWESLRFGEYGDPLQCGAWVGQCALYIVIMIFEKSVVFIVLLILQWKKVALLNPIENPDLKLAIVMLIVPFFVNAFMFWVVDNFLMRKGKTKAKLEERGANQDSRNGSKVRYRRAASHEESESEILISADDEMEESDAEEDLRRPVKKKHRFGLPV", "length": 288 }, "evidence": [ { "id": "F6RY84", "url": "https://omabrowser.org/oma/group/F6RY84/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q7TSW6-1", "protein_name": "Store-operated calcium entry regulator STIMATE", "gene_name": "Stimate", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MQGPGGNVSRGLPGGPASTVASGAGRCESGALMHSFGIFLQGLLGVVAFSTLMLKRFREPKHERRPWRIWFLDTSKQAIGMLFIHFANVYLADLTEEDPCSLYLINFLLDATVGMLLIYVGVRAVGVLVEWQQWESLRFGEYGDPLQCGAWVGQCALYIVIMIFEKSVVFIVLLILQWKKVALLNPIENPDLKLAIVMLIVPFFVNAFMFWVVDNFLMRKGKTKAKLEERGANQDSRNGSKVRYRRAASHEESESEILISADDEMEESDAEEDLRRPVKKKHRFGLPV", "length": 288 }, "evidence": [ { "id": "F6RY84", "url": "https://omabrowser.org/oma/group/F6RY84/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" } ], "go_annotation": { "categories": [ { "name": "Molecular Function", "total": 1, "go_terms": [ { "name": "calcium channel regulator activity", "id": "GO:0005246", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005246", "evidence": [ { "database": "UniProtKB", "id": "F6RY84", "url": "https://www.uniprot.org/uniprotkb/F6RY84" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 4, "go_terms": [ { "name": "endoplasmic reticulum membrane", "id": "GO:0005789", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005789", "evidence": [ { "database": "UniProtKB", "id": "F6RY84", "url": "https://www.uniprot.org/uniprotkb/F6RY84" } ], "pmid": "" }, { "name": "cortical endoplasmic reticulum", "id": "GO:0032541", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0032541", "evidence": [ { "database": "UniProtKB", "id": "F6RY84", "url": "https://www.uniprot.org/uniprotkb/F6RY84" } ], "pmid": "" }, { "name": "endoplasmic reticulum-plasma membrane contact site", "id": "GO:0140268", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0140268", "evidence": [ { "database": "UniProtKB", "id": "F6RY84", "url": "https://www.uniprot.org/uniprotkb/F6RY84" } ], "pmid": "" }, { "name": "membrane", "id": "GO:0016020", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016020", "evidence": [ { "database": "UniProtKB", "id": "F6RY84", "url": "https://www.uniprot.org/uniprotkb/F6RY84" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 1, "go_terms": [ { "name": "store-operated calcium entry", "id": "GO:0002115", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0002115", "evidence": [ { "database": "UniProtKB", "id": "F6RY84", "url": "https://www.uniprot.org/uniprotkb/F6RY84" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 238, "end_pos": 240, "annotation": "n_glycosylation_sequon" }, { "start_pos": 7, "end_pos": 9, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [ { "pdb_id": "AF-F6RY84-F1", "pdb_chain": "global", "start_pos": 1, "end_pos": 294, "overlap": "1.0", "method": "AlphaFold", "type": "alphafold", "resolution": -1.0, "url": "https://data.glygen.org/ln2downloads/pdb/current/AF-F6RY84-F1.pdb", "url_external": "https://alphafold.ebi.ac.uk/entry/F6RY84" } ], "lectin_list": [], "domain_list": [], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], 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"https://www.ebi.ac.uk/interpro/entry/IPR001331", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR001849", "url": "https://www.ebi.ac.uk/interpro/entry/IPR001849", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR011993", "url": "https://www.ebi.ac.uk/interpro/entry/IPR011993", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR035899", "url": "https://www.ebi.ac.uk/interpro/entry/IPR035899", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR040655", "url": "https://www.ebi.ac.uk/interpro/entry/IPR040655", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR043537", "url": "https://www.ebi.ac.uk/interpro/entry/IPR043537", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR055230", "url": "https://www.ebi.ac.uk/interpro/entry/IPR055230", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "RINRHIN", "url": "https://omabrowser.org/oma/group/RINRHIN/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "F1MX58", "url": "https://www.orthodb.org/?gene=F1MX58", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "G3MXA5", "url": "https://www.orthodb.org/?gene=G3MXA5", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR46001", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR46001", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR46001:SF1", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR46001:SF1", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00169", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00169", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF00621", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00621", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF18385", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF18385", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF23014", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF23014", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "F1MX58", "url": "https://www.uniprot.org/uniprotkb/F1MX58", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "F1MX58-1", "url": "https://www.uniprot.org/uniprotkb/F1MX58-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "G3MXA5", "url": "https://www.uniprot.org/uniprotkb/G3MXA5", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "G3MXA5-1", "url": "https://www.uniprot.org/uniprotkb/G3MXA5-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MGNAESQSVVHEFYGDKHAVLGRKHTSRSLRLSHKARRTRHASSGKVIHRNSEVSTRSSSTPSIPQSLAENGLEPFSQEGTLEDFGSPIWVDRVDVGLRPVSYTDSSVAPSVDSSIVLTAASVQSMPDSEDSRLYGDDATYLAEGGRRQRPYASNGPAFMETASFKKKRSKSADIWREDSLEFSLSDLSQEHLTSNEEILGSAEEKDCEEARAMETRASPRQLSACQRANSLGDLYAQKNSGVTANGGPRSKLAGYCRNLVSDIPDLANHKMPPAAAEEALPYSNYNTLPCRKSHCLSEGATNPQISHSSSMQGRRAKTTQDVNAGEGSEFADSGIEGATTDTDLLSRRSNATNSSYSPPTGRAFVGSDSGSSSTGDAARQGVYENFRRELEMSTTNSESLEEAGSTHSDEQSSGTLSSPGQSDILLTAAQGTVRKAGALAVKNFLVHKKNKKVESATRRKWKHYWVSLKGCTLFFYEGDGRSGIDHNSVPKHAVWVENSIVQAVPEHPKKDFVFCLSNSLGDAFLFQTTSQTELENWITAIHSACAAAVARHHHKEDTLRLLKSEIKKLEQKIDMDEKMKKMGEMQLSSVTDSKKKKTILDQVIVLPCTDVGQSSGLERGVSAALEPRNILGYLLLVSLSPRLLDSLF", "length": 649, "header": "tr|G3MXA5-1|G3MXA5_BOVIN Isoform 1 of PH domain-containing protein OS=Bos taurus OX=9913 GN=TIAM1 PE=4 SV=4 CANONICAL=G3MXA5-1" }, "isoforms": [ { "isoform_ac": "F1MX58-1", "url": "https://www.uniprot.org/uniprotkb/F1MX58/entry", "sequence": { "sequence": 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"https://www.ensembl.org/id/ENSBTAT00000023716.8" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000023716.6", "url": "https://www.ensembl.org/id/ENSBTAP00000023716.6" } ] } }, { "isoform_ac": "G3MXA5-1", "url": "https://www.uniprot.org/uniprotkb/G3MXA5/entry", "sequence": { "sequence": "MGNAESQSVVHEFYGDKHAVLGRKHTSRSLRLSHKARRTRHASSGKVIHRNSEVSTRSSSTPSIPQSLAENGLEPFSQEGTLEDFGSPIWVDRVDVGLRPVSYTDSSVAPSVDSSIVLTAASVQSMPDSEDSRLYGDDATYLAEGGRRQRPYASNGPAFMETASFKKKRSKSADIWREDSLEFSLSDLSQEHLTSNEEILGSAEEKDCEEARAMETRASPRQLSACQRANSLGDLYAQKNSGVTANGGPRSKLAGYCRNLVSDIPDLANHKMPPAAAEEALPYSNYNTLPCRKSHCLSEGATNPQISHSSSMQGRRAKTTQDVNAGEGSEFADSGIEGATTDTDLLSRRSNATNSSYSPPTGRAFVGSDSGSSSTGDAARQGVYENFRRELEMSTTNSESLEEAGSTHSDEQSSGTLSSPGQSDILLTAAQGTVRKAGALAVKNFLVHKKNKKVESATRRKWKHYWVSLKGCTLFFYEGDGRSGIDHNSVPKHAVWVENSIVQAVPEHPKKDFVFCLSNSLGDAFLFQTTSQTELENWITAIHSACAAAVARHHHKEDTLRLLKSEIKKLEQKIDMDEKMKKMGEMQLSSVTDSKKKKTILDQVIVLPCTDVGQSSGLERGVSAALEPRNILGYLLLVSLSPRLLDSLF", "length": 649, "header": "tr|G3MXA5-1|G3MXA5_BOVIN Isoform 1 of PH domain-containing protein OS=Bos taurus OX=9913 GN=TIAM1 PE=4 SV=4 CANONICAL=G3MXA5-1" }, "locus": { "chromosome": "1", "start_pos": 4311774, "end_pos": 4271804, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000064124.4", "url": "https://www.ensembl.org/id/ENSBTAT00000064124.4" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000054169.4", "url": "https://www.ensembl.org/id/ENSBTAP00000054169.4" } ] } } ], "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "other", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 61, "start_aa": "Thr", "end_pos": 61, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr61", "evidence": [ { "id": "", "database": "GlyGen", "url": "https://data.glygen.org/" } ], "filter_code": "000000000000000010000.00000000001000.0.01000" } ], "phosphorylation": [], "glycation": [], "keywords": [ "glycoprotein", "glycoprotein_predicted" ], "publication": [], "pathway": [], "orthologs": [], "go_annotation": { "categories": [ { "name": "Molecular Function", "total": 1, "go_terms": [ { "name": "guanyl-nucleotide exchange factor activity", "id": "GO:0005085", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005085", "evidence": [ { "database": "UniProtKB", "id": "G3MXA5", "url": "https://www.uniprot.org/uniprotkb/G3MXA5" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 1, "go_terms": [ { "name": "small GTPase-mediated signal transduction", "id": "GO:0007264", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007264", "evidence": [ { "database": "UniProtKB", "id": "G3MXA5", "url": "https://www.uniprot.org/uniprotkb/G3MXA5" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 351, "end_pos": 353, "annotation": "n_glycosylation_sequon" }, { "start_pos": 354, "end_pos": 356, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "G3MXA5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3MXA5" }, { "id": "PS50003", "database": "PROSITE", "url": "https://prosite.expasy.org/PS50003" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "PH", "eco_id": "ECO_0000259", "start_pos": 439, "end_pos": 547, "start_aa": "Ala", "end_aa": "Ala", "glycosite_overlap": [] } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [ 61 ], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 351, "end_pos": 353 }, { "start_pos": 354, "end_pos": 356 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 1 }, { "field": "total_sites", "count": 1 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 1 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "exact_sites", "count": 1 }, { "field": "exact_o_linked_sites", "count": 1 }, { "field": "fuzzy_sites", "count": 0 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_pos", "start_aa", "end_pos", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": 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"url": "https://www.uniprot.org/uniprotkb/G3X7H1" } ] } ], "protein_names": [ { "name": "Caspase-14", "type": "recommended", "evidence": [ { "id": "G3X7H1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3X7H1/entry#names_and_taxonomy" } ] } ], "function": [], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Bos taurus", "taxid": 9913, "evidence": [ { "database": "UniProtKB", "id": "G3X7H1", "url": "https://www.uniprot.org/uniprotkb/G3X7H1" } ], "common_name": "Bovine", "glygen_name": "Bovine", "reference_species": "Bos taurus [9913]" } ], "gene": [ { "name": "CASP14", "url": "https://www.uniprot.org/uniprotkb/G3X7H1", "locus": { "chromosome": "7", "start_pos": 8098449, "end_pos": 8113890, "strand": "+", "evidence": [ { "database": "Ensembl Gene", "id": "ENSBTAG00000021106", "url": "https://www.ensembl.org/id/ENSBTAG00000021106" } ] } } ], "crossref": [ { "id": "G3X7H1", "url": "https://alphafold.ebi.ac.uk/entry/G3X7H1", "database": "AlphaFoldDB", "categories": [] }, { "id": "ENSBTAG00000021106", "url": "https://bgee.org/?page=gene&gene_id=ENSBTAG00000021106", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "cd00032", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd00032", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "IPR001309", "url": "https://www.ebi.ac.uk/interpro/entry/IPR001309", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR002138", "url": "https://www.ebi.ac.uk/interpro/entry/IPR002138", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR011600", "url": "https://www.ebi.ac.uk/interpro/entry/IPR011600", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR015917", "url": "https://www.ebi.ac.uk/interpro/entry/IPR015917", "database": "InterPro", "categories": [ "Protein Classification" ] }, { 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"PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00656", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00656", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "R-BTA-6809371", "url": "https://www.reactome.org/PathwayBrowser/#R-BTA-6809371", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "G3X7H1", "url": "https://www.uniprot.org/uniprotkb/G3X7H1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "G3X7H1-1", "url": "https://www.uniprot.org/uniprotkb/G3X7H1-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "ESKEMSSPQPLEEETYDMSGARLALTLCVTKAREGSEADLDALERMFQQLGFESTMKRDPTAQQFQEELEKFQQAIDAREDFVSCAFVVLMAHGLEGRLKGKDEKMVELEDLFQALNNKNCRALRAKPKVYIVQACRGEQRDPGEPVTGGHLVMITENTPETIPTYTDTLHVFSTIEGYIAYRHDQEGSYFIQTLVDVFINKKGPILELLTEVTRRMAEAEMVQEGEAKKVNPEIQSTLRKQLYLQ", "length": 246, "header": "tr|G3X7H1-1|G3X7H1_BOVIN Isoform 1 of Caspase-14 OS=Bos taurus OX=9913 GN=CASP14 PE=1 SV=1 CANONICAL=G3X7H1-1" }, "isoforms": [ { "isoform_ac": "G3X7H1-1", "url": "https://www.uniprot.org/uniprotkb/G3X7H1/entry", "sequence": { "sequence": "ESKEMSSPQPLEEETYDMSGARLALTLCVTKAREGSEADLDALERMFQQLGFESTMKRDPTAQQFQEELEKFQQAIDAREDFVSCAFVVLMAHGLEGRLKGKDEKMVELEDLFQALNNKNCRALRAKPKVYIVQACRGEQRDPGEPVTGGHLVMITENTPETIPTYTDTLHVFSTIEGYIAYRHDQEGSYFIQTLVDVFINKKGPILELLTEVTRRMAEAEMVQEGEAKKVNPEIQSTLRKQLYLQ", "length": 246, "header": "tr|G3X7H1-1|G3X7H1_BOVIN Isoform 1 of Caspase-14 OS=Bos taurus OX=9913 GN=CASP14 PE=1 SV=1 CANONICAL=G3X7H1-1" }, "locus": { "chromosome": "7", "start_pos": 8103066, "end_pos": 8099453, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000028116.4", "url": "https://www.ensembl.org/id/ENSBTAT00000028116.4" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000028116.2", "url": "https://www.ensembl.org/id/ENSBTAP00000028116.2" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], 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"common_name": "Human" } ], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 4, "go_terms": [ { "name": "nucleoplasm", "id": "GO:0005654", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005654", "evidence": [ { "database": "UniProtKB", "id": "G3X7H1", "url": "https://www.uniprot.org/uniprotkb/G3X7H1" } ], "pmid": "" }, { "name": "cytoplasm", "id": "GO:0005737", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005737", "evidence": [ { "database": "UniProtKB", "id": "G3X7H1", "url": "https://www.uniprot.org/uniprotkb/G3X7H1" } ], "pmid": "" }, { "name": "cytosol", "id": "GO:0005829", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005829", "evidence": [ { "database": "UniProtKB", "id": "G3X7H1", "url": "https://www.uniprot.org/uniprotkb/G3X7H1" } ], "pmid": "" }, { "name": "cornified envelope", "id": "GO:0001533", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0001533", "evidence": [ { "database": "UniProtKB", "id": "G3X7H1", "url": "https://www.uniprot.org/uniprotkb/G3X7H1" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 3, "go_terms": [ { "name": "proteolysis", "id": "GO:0006508", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006508", "evidence": [ { "database": "UniProtKB", "id": "G3X7H1", "url": "https://www.uniprot.org/uniprotkb/G3X7H1" } ], "pmid": "" }, { "name": "cell differentiation", "id": "GO:0030154", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030154", "evidence": [ { "database": "UniProtKB", "id": "G3X7H1", "url": "https://www.uniprot.org/uniprotkb/G3X7H1" } ], "pmid": "" }, { "name": "positive regulation of neuron apoptotic process", "id": "GO:0043525", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0043525", "evidence": [ { "database": "UniProtKB", "id": "G3X7H1", "url": "https://www.uniprot.org/uniprotkb/G3X7H1" } ], "pmid": "" } ] }, { "name": "Molecular Function", "total": 1, "go_terms": [ { "name": "cysteine-type endopeptidase activity", "id": "GO:0004197", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0004197", "evidence": [ { "database": "UniProtKB", "id": "G3X7H1", "url": "https://www.uniprot.org/uniprotkb/G3X7H1" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "G3X7H1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3X7H1" }, { "id": "PS50207", "database": "PROSITE", "url": "https://prosite.expasy.org/PS50207" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "Caspase family p10", "eco_id": "ECO_0000259", "start_pos": 159, "end_pos": 246, "start_aa": "Thr", "end_aa": "Gln", "glycosite_overlap": [] }, { "evidence": [ { "id": "G3X7H1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3X7H1" }, { "id": "PS50208", "database": "PROSITE", "url": 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"type": "recommended", "evidence": [ { "id": "F6RKW3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F6RKW3" } ] }, { "name": "SPN", "type": "synonym", "evidence": [ { "id": "NP_001096572", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001096572" } ] } ], "protein_names": [ { "name": "Sialophorin", "type": "synonym", "evidence": [ { "id": "F6RKW3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F6RKW3/entry#names_and_taxonomy" } ] }, { "name": "leukosialin", "type": "synonym", "evidence": [ { "id": "NP_001096572", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001096572" } ] }, { "name": "sialophorin (leukosialin, CD43)", "type": "synonym", "evidence": [ { "id": "NP_001096572", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001096572" } ] } ], "function": [], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": 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"Bos taurus [9913]" } ], "gene": [ { "name": "", "url": "https://www.uniprot.org/uniprotkb/F6RLW2", "locus": {} } ], "crossref": [ { "id": "F6RLW2", "url": "https://alphafold.ebi.ac.uk/entry/F6RLW2", "database": "AlphaFoldDB", "categories": [] }, { "id": "IPR002494", "url": "https://www.ebi.ac.uk/interpro/entry/IPR002494", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR052154", "url": "https://www.ebi.ac.uk/interpro/entry/IPR052154", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "PTHR48425", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR48425", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR48425:SF1", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR48425:SF1", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF01500", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF01500", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "F6RLW2", "url": "https://www.uniprot.org/uniprotkb/F6RLW2", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "F6RLW2-1", "url": "https://www.uniprot.org/uniprotkb/F6RLW2-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MTVSCCGPTFSSFSCGRGCLQPCCYRDPCCCRPVSCQTTVSRPVTCVPRCTRPICEPCRRPPCCYRDPCCCRPVSCQTTVSRPVTCVPRCTRPICEPCRRPVCCDPCSLQEGCCRPITCCPTSCQAVVCRPCCWATTCCQPISVQSPCCRPTCCRPAPCRTTCRTC", "length": 166, "header": "tr|F6RLW2-1|F6RLW2_BOVIN Isoform 1 of Uncharacterized protein OS=Bos taurus OX=9913 GN= PE=4 SV=1 CANONICAL=F6RLW2-1" }, "isoforms": [ { "isoform_ac": "F6RLW2-1", "url": "https://www.uniprot.org/uniprotkb/F6RLW2/entry", "sequence": { "sequence": "MTVSCCGPTFSSFSCGRGCLQPCCYRDPCCCRPVSCQTTVSRPVTCVPRCTRPICEPCRRPPCCYRDPCCCRPVSCQTTVSRPVTCVPRCTRPICEPCRRPVCCDPCSLQEGCCRPITCCPTSCQAVVCRPCCWATTCCQPISVQSPCCRPTCCRPAPCRTTCRTC", "length": 166, "header": "tr|F6RLW2-1|F6RLW2_BOVIN Isoform 1 of Uncharacterized protein OS=Bos taurus OX=9913 GN= PE=4 SV=1 CANONICAL=F6RLW2-1" }, "locus": { "chromosome": "19", "start_pos": 41267555, "end_pos": 41253674, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000056308.3", "url": "https://www.ensembl.org/id/ENSBTAT00000056308.3" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000050021.2", "url": "https://www.ensembl.org/id/ENSBTAP00000050021.2" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [], "orthologs": [], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 2, "go_terms": [ { "name": "cytosol", "id": "GO:0005829", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005829", "evidence": [ { "database": "UniProtKB", "id": "F6RLW2", "url": "https://www.uniprot.org/uniprotkb/F6RLW2" } ], "pmid": "" }, { "name": "keratin filament", "id": "GO:0045095", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0045095", "evidence": [ { "database": "UniProtKB", "id": "F6RLW2", "url": "https://www.uniprot.org/uniprotkb/F6RLW2" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": 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"total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ], "tool_support": { "graph_view": "yes" } }, { "uniprot_canonical_ac": "F6RM04-1", "uniprot_ac": "F6RM04", "uniprot_id": "F6RM04_BOVIN", "mass": { "chemical_mass": 97281.0, "monoisotopic_mass": 97281.0 }, "refseq": { "ac": "NP_001193510", "name": "putative RNA-binding protein 15B", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001193510" }, "gene_names": [ { "name": "RBM15B", "type": "recommended", "evidence": [ { "id": "F6RM04", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F6RM04" } ] }, { "name": "RBM15B", "type": "synonym", "evidence": [ { "id": "NP_001193510", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001193510" } ] } ], "protein_names": [ { "name": "Putative RNA-binding protein 15B", "type": "recommended", "evidence": [ { "id": "F6RM04", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F6RM04/entry#names_and_taxonomy" } ] }, { "name": "RNA-binding motif protein 15B", "type": "synonym", "evidence": [ { "id": "F6RM04", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F6RM04/entry#names_and_taxonomy" } ] }, { "name": "putative RNA-binding protein 15B", "type": "synonym", "evidence": [ { "id": "NP_001193510", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001193510" } ] } ], "function": [], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Bos taurus", "taxid": 9913, "evidence": [ { "database": "UniProtKB", "id": "F6RM04", "url": "https://www.uniprot.org/uniprotkb/F6RM04" } ], "common_name": "Bovine", "glygen_name": "Bovine", "reference_species": "Bos taurus [9913]" } ], "gene": [ { "name": "RBM15B", "url": "https://www.uniprot.org/uniprotkb/F6RM04", "locus": { "chromosome": "22", "start_pos": 49365407, "end_pos": 49378385, "strand": "+", "evidence": [ { "database": "Ensembl Gene", "id": "ENSBTAG00000006500", "url": "https://www.ensembl.org/id/ENSBTAG00000006500" } ] } } ], "crossref": [ { "id": "ENSBTAG00000006500", "url": "https://bgee.org/?page=gene&gene_id=ENSBTAG00000006500", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "cd12554", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd12554", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "cd12556", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd12556", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "cd12558", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd12558", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "cd21550", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd21550", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "508868", "url": "https://www.ncbi.nlm.nih.gov/gene/508868", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR000504", "url": "https://www.ebi.ac.uk/interpro/entry/IPR000504", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR010912", "url": "https://www.ebi.ac.uk/interpro/entry/IPR010912", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR012677", "url": "https://www.ebi.ac.uk/interpro/entry/IPR012677", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR012921", "url": "https://www.ebi.ac.uk/interpro/entry/IPR012921", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR016194", "url": "https://www.ebi.ac.uk/interpro/entry/IPR016194", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR034475", "url": "https://www.ebi.ac.uk/interpro/entry/IPR034475", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR034535", "url": "https://www.ebi.ac.uk/interpro/entry/IPR034535", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR034536", "url": "https://www.ebi.ac.uk/interpro/entry/IPR034536", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR035979", "url": "https://www.ebi.ac.uk/interpro/entry/IPR035979", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "bta:508868", "url": "https://www.genome.jp/dbget-bin/www_bget?bta:508868", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "GLFRQFQ", "url": "https://omabrowser.org/oma/group/GLFRQFQ/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "F6RM04", "url": "https://www.orthodb.org/?gene=F6RM04", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR23189", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR23189", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00076", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00076", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF07744", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF07744", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "NP_001193510", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001193510", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "F6RM04", "url": "https://www.uniprot.org/uniprotkb/F6RM04", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "F6RM04-1", "url": "https://www.uniprot.org/uniprotkb/F6RM04-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MKRQSERDSSPSGRGSSSSAKRPREREREAEAGGRRAAHKASGGAKHPVPTRARDKPRGSGGSGGGHRDGRGAGDANHRASSGRSSGSGAGGGGRGGKASGDPGASGASPRASPLPPPPPPPGAEPTGPGSSAAAPEYKTLLISSLSPALPAEHLEDRLFHQFKRFGEISLRLSHTPELGRVAYVNFRHPQDAREARQHALARQLLLYDRPLKVEPVYLRGGGGGGGSSRRSSSSSAAASTPPPGPPAPADPLGYLPLHGGYQYKQRSLSPVAAPPLREPRARHAAAAFALDAAAAAAAVGLSRERALDYYGLYDDRGRPYGYPAVCEEDLMPEDDQRATRNLFIGNLDHSVSEVELRRAFEKYGIIEEVVIKRPARGQGGAYAFLKFQNLDMAHRAKVGMSGRVIGRNPIKIGYGKANPTTRLWVGGLGPNTSLAALAREFDRFGSIRTIDHVKGDSFAYIQYESLDAAQAACAKMRGFPLGGPDRRLRVDFAKAEETRYPQQYQPSPLPVHYELLPDGYTRHRNLDADLRVRDRTPPHLLYSDRERTFLEGDWTSPSKSSDRRNSLEGYSRSVRSRSGERWGGDGDRGLPKAWEDRRKRRSLSSDRGRATHSPYEERSRTKGGGQPADRGSDRTPERSRKENHSSEGTKESGSNSLSNSRHGAEERSHHHHHEAPDSSHGKKTRESERNHRTTEAEPKPLEEPKHETKKLKNLSEYAQTLQLGWNGLLVLKNSCFPTSMHILEGDQGVISSLLKDHTSGSKLTQLKIAQRLRLDQPKLDEVTRRIKQGSPNGYAVLLATQATPSGPGSEGMPTVEPGLQRRLLRNLVSYLKQKQAAGVISLPVGGSKGRDSTGMLYAFPPCDFSQQYLQSALRTLGKLEEEHMVIVIVRDTA", "length": 894, "header": "tr|F6RM04-1|F6RM04_BOVIN Isoform 1 of Putative RNA-binding protein 15B OS=Bos taurus OX=9913 GN=RBM15B PE=3 SV=2 CANONICAL=F6RM04-1" }, "isoforms": [ { "isoform_ac": "F6RM04-1", "url": "https://www.uniprot.org/uniprotkb/F6RM04/entry", "sequence": { "sequence": "MKRQSERDSSPSGRGSSSSAKRPREREREAEAGGRRAAHKASGGAKHPVPTRARDKPRGSGGSGGGHRDGRGAGDANHRASSGRSSGSGAGGGGRGGKASGDPGASGASPRASPLPPPPPPPGAEPTGPGSSAAAPEYKTLLISSLSPALPAEHLEDRLFHQFKRFGEISLRLSHTPELGRVAYVNFRHPQDAREARQHALARQLLLYDRPLKVEPVYLRGGGGGGGSSRRSSSSSAAASTPPPGPPAPADPLGYLPLHGGYQYKQRSLSPVAAPPLREPRARHAAAAFALDAAAAAAAVGLSRERALDYYGLYDDRGRPYGYPAVCEEDLMPEDDQRATRNLFIGNLDHSVSEVELRRAFEKYGIIEEVVIKRPARGQGGAYAFLKFQNLDMAHRAKVGMSGRVIGRNPIKIGYGKANPTTRLWVGGLGPNTSLAALAREFDRFGSIRTIDHVKGDSFAYIQYESLDAAQAACAKMRGFPLGGPDRRLRVDFAKAEETRYPQQYQPSPLPVHYELLPDGYTRHRNLDADLRVRDRTPPHLLYSDRERTFLEGDWTSPSKSSDRRNSLEGYSRSVRSRSGERWGGDGDRGLPKAWEDRRKRRSLSSDRGRATHSPYEERSRTKGGGQPADRGSDRTPERSRKENHSSEGTKESGSNSLSNSRHGAEERSHHHHHEAPDSSHGKKTRESERNHRTTEAEPKPLEEPKHETKKLKNLSEYAQTLQLGWNGLLVLKNSCFPTSMHILEGDQGVISSLLKDHTSGSKLTQLKIAQRLRLDQPKLDEVTRRIKQGSPNGYAVLLATQATPSGPGSEGMPTVEPGLQRRLLRNLVSYLKQKQAAGVISLPVGGSKGRDSTGMLYAFPPCDFSQQYLQSALRTLGKLEEEHMVIVIVRDTA", "length": 894, "header": "tr|F6RM04-1|F6RM04_BOVIN Isoform 1 of Putative RNA-binding protein 15B OS=Bos taurus OX=9913 GN=RBM15B PE=3 SV=2 CANONICAL=F6RM04-1" }, "locus": { "chromosome": "22", "start_pos": 49366589, "end_pos": 49365925, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000092714.2", "url": "https://www.ensembl.org/id/ENSBTAT00000092714.2" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000101529.1", "url": "https://www.ensembl.org/id/ENSBTAP00000101529.1" } ] } } ], "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "other", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 127, "start_aa": "Thr", "end_pos": 127, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr127", "evidence": [ { "id": "", "database": "GlyGen", "url": "https://data.glygen.org/" } ], "filter_code": "000000000000000010000.00000000001000.0.01000" }, { "glytoucan_ac": "", "type": "O-linked", "subtype": "other", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 804, "start_aa": "Thr", "end_pos": 804, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr804", "evidence": [ { "id": "", "database": "GlyGen", "url": "https://data.glygen.org/" } ], "filter_code": "000000000000000010000.00000000001000.0.01000" } ], "phosphorylation": [], "glycation": [], "keywords": [ "glycoprotein", "glycoprotein_predicted" ], "publication": [], "pathway": [ { "id": "bta:508868", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?bta:508868", "resource": "KEGG Pathway" } ], "orthologs": [ { "uniprot_canonical_ac": "A0A8V1A818-1", "protein_name": "Putative RNA-binding protein 15B", "gene_name": "RBM15B", "tax_id": 9031, "organism": "Gallus gallus", "sequence": { "sequence": "MKRGSERDASPPGAGGGRAAAAKRPRERERESSSRRGPHRSSGASRSSRDKSTPGGGGGGGGGGGGSGGSGGGGSGSRSHRGDERAGGADSNHRPAASGSASGARGQAAPSSSSSSSSSSRALGVPKAKALPGAVVAPSLLLAGPPPGAAPSLLLAPLGGSAGLAGEPPGSCEYKTLLVSGLSAALPDQLLEDGLFRLFQRFAGGGAGDISVKLSHTPELGRVAYVNFRHPGDARDARRHARARQLLLYDRPLKVEPVYLRGGRRSRTPPPAPSPEPLGYLPPLHGAYQYKQRSLSPVTSPLLREPRPRHAHAAAAAFALEAAAIGLSRERERALDYYGLYDERGRPYSYPIVAEEDLMPEDDQRATRNLFIGNLDHNVSEVELRRAFEKYGIIEEVVIKRPARGQGGAYAFLKFQNLDMAHRAKVAMSGRVVGRNPIKIGYGKANPTTRLWVGGLGPSTSLAALAREFDRFGSIRTIDYVKGDSFAYIQYESLDAAQAACAQMRGFPLGGPERRLRVDFAKAEETRYPQQYQPAPLPVHYELLADGYSRHRSLEQDLRVRDRTPPHLLYSDRDRSFAEADWASPAKNAERRNNLEGYSRSVRSRSGERWASDSDRAVPKLWEERRKRRSLSSDRGRTAHSPYEDRSRTKASGPALDRSPERARKENHTTESGTEKEQSNSLQNNRHATEEKPHREASDAPQPKKRDSERNHRTGESESKAHEEPKSETKKLKNLSEYAQTLQLAWNGLLVLKNSCFPTSMHILEGDLGVINGLLKDHSSGGKLTQLKIAQRLRLDQPKLDEVTRRIKQGSPNGYAVLLATQSAPGGAGAEGTFPVVEPGLQRRLLRNLVSYLKQKQAAGVISLPVGGAKGRDSTGMLYAFPPCEFSQQYLQSALRTLGKLEEEHMVIVIVKDTA", "length": 915 }, "evidence": [ { "id": "F6RM04", "url": "https://omabrowser.org/oma/group/F6RM04/", "database": "OMA" } ], "glygen_name": "Chicken", "common_name": "Chicken" }, { "uniprot_canonical_ac": "D3ZHD6-1", "protein_name": "Putative RNA-binding protein 15B", "gene_name": "Rbm15b", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MKRQNERDSSPSGRGSSSSAKRPREREREAEAGGRRAAHKASGGTKHPVPARARDKPRGSGGGGGHRDGRAAGDANHRASSGRSSGAPGGGGRTGKASGDPGAGGASPRASPLPPPPPPPGAEPAGPGTTAAPEYKTLLISSLSPALPAEHLEDRLFHQFKRFGEISLRLSHTPELGRVAYVNFRHPQDAREARQHALARQLLLYDRPLKVEPVYLRGGGSSRRSSSSSAAASTPPPGPPTPADPLGYLPLHGGYQYKQRSLSPVAAPPLREPRARHAAAAFALDAAAAAAVGLSRERALDYYGLYDDRGRPYSYQAVCEEDLMPEDDQRATRNLFIGNLDHSVSEVELRRAFEKYGIIEEVVIKRPARGQGGAYAFLKFQNLDMAHRAKVAMSGRVIGRNPIKIGYGKANPTTRLWVGGLGPNTSLAALAREFDRFGSIRTIDHVKGDSFAYIQYESLDAAQAACAKMRGFPLGGPDRRLRVDFAKAEETRYPQQYQPSPLPVHYELLTDGYTRHRNLDADLRVRDRTPPHLLYSDRDRTFLEGDWTSLSKSSDRRNSLEGYSRSVRSRSGERWGADGDRSIAKPWEERRKRRSLSSDRGRTTHSPYEERSRTKGGGQQSERGSDRTPERSRKENHSSEGTKESGSNSLSNSRHSAEERSHHHHHHEAPDSSHGKKTRESERNHRTTEAEPKTLEEPKHETKKLKTLSEYAQTLQLGWNGLLVLKNSCFPTSMHILEGDQGVISGLLKDHTSGSKLTQLKIAQRLRLDQPKLDEVTRRIKQGSPNGYAVLLAIQSTPSGPGAEGMPMVEPGLQRRLLRNLVSYLKQKQAAGVISLPVGGSKGRDSTGMLYAFPPCDFSQQYLQSALRTLGKLEEEHMVIVIVRDAA", "length": 887 }, "evidence": [ { "id": "F6RM04", "url": "https://omabrowser.org/oma/group/F6RM04/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "F1SIZ8-1", "protein_name": "Putative RNA-binding protein 15B", "gene_name": "RBM15B", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": 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"database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "Q6PHZ5-1", "protein_name": "Putative RNA-binding protein 15B", "gene_name": "Rbm15b", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": 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"database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q8NDT2-1", "protein_name": "Putative RNA-binding protein 15B", "gene_name": "RBM15B", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": 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"database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" } ], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 4, "go_terms": [ { "name": "RNA N6-methyladenosine methyltransferase complex", "id": "GO:0036396", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0036396", "evidence": [ { "database": "UniProtKB", "id": "F6RM04", "url": "https://www.uniprot.org/uniprotkb/F6RM04" } ], "pmid": "" }, { "name": "nucleus", "id": "GO:0005634", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005634", "evidence": [ { "database": "UniProtKB", "id": "F6RM04", "url": "https://www.uniprot.org/uniprotkb/F6RM04" } ], "pmid": "" }, { "name": "nuclear envelope", "id": "GO:0005635", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005635", "evidence": [ { "database": "UniProtKB", "id": "F6RM04", "url": "https://www.uniprot.org/uniprotkb/F6RM04" } ], "pmid": "" }, { "name": "nuclear speck", "id": "GO:0016607", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016607", "evidence": [ { "database": "UniProtKB", "id": "F6RM04", "url": "https://www.uniprot.org/uniprotkb/F6RM04" } ], "pmid": "" } ] }, { "name": "Molecular Function", "total": 1, "go_terms": [ { "name": "mRNA binding", "id": "GO:0003729", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003729", "evidence": [ { "database": "UniProtKB", "id": "F6RM04", "url": "https://www.uniprot.org/uniprotkb/F6RM04" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 7, "go_terms": [ { "name": "DNA-templated transcription", "id": "GO:0006351", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006351", "evidence": [ { "database": "UniProtKB", "id": "F6RM04", "url": "https://www.uniprot.org/uniprotkb/F6RM04" } ], "pmid": "" }, { "name": "mRNA processing", "id": "GO:0006397", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006397", "evidence": [ { "database": "UniProtKB", "id": "F6RM04", "url": "https://www.uniprot.org/uniprotkb/F6RM04" } ], "pmid": "" }, { "name": "mRNA export from nucleus", "id": "GO:0006406", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006406", "evidence": [ { "database": "UniProtKB", "id": "F6RM04", "url": "https://www.uniprot.org/uniprotkb/F6RM04" } ], "pmid": "" }, { "name": "RNA splicing", "id": "GO:0008380", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008380", "evidence": [ { "database": "UniProtKB", "id": "F6RM04", "url": "https://www.uniprot.org/uniprotkb/F6RM04" } ], "pmid": "" }, { "name": "dosage compensation by inactivation of X chromosome", "id": "GO:0009048", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0009048", "evidence": [ { "database": "UniProtKB", "id": "F6RM04", "url": "https://www.uniprot.org/uniprotkb/F6RM04" } ], "pmid": "" }, { "name": "RNA methylation", "id": "GO:0001510", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0001510", "evidence": [ { "database": "UniProtKB", "id": "F6RM04", "url": "https://www.uniprot.org/uniprotkb/F6RM04" } ], "pmid": "" }, { "name": "regulation of alternative mRNA splicing, via spliceosome", "id": 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"url": "https://www.uniprot.org/uniprotkb/F6RMD1/entry#names_and_taxonomy" } ] } ], "function": [], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Bos taurus", "taxid": 9913, "evidence": [ { "database": "UniProtKB", "id": "F6RMD1", "url": "https://www.uniprot.org/uniprotkb/F6RMD1" } ], "common_name": "Bovine", "glygen_name": "Bovine", "reference_species": "Bos taurus [9913]" } ], "gene": [ { "name": "TMEM9B", "url": "https://www.uniprot.org/uniprotkb/F6RMD1", "locus": { "chromosome": "15", "start_pos": 43643807, "end_pos": 43624932, "strand": "-", "evidence": [ { "database": "Ensembl Gene", "id": "ENSBTAG00000008310", "url": "https://www.ensembl.org/id/ENSBTAG00000008310" } ] } } ], "crossref": [ { "id": "F6RMD1", "url": "https://alphafold.ebi.ac.uk/entry/F6RMD1", "database": "AlphaFoldDB", "categories": [] }, { "id": "515665", "url": "https://www.ncbi.nlm.nih.gov/gene/515665", "database": "GeneID", "categories": 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mapped isoform of TMEM9 domain family member B OS=Bos taurus OX=9913 GN=TMEM9B PE=3 SV=1 CANONICAL=F6RMD1-1" }, "locus": { "chromosome": "15", "start_pos": 43642669, "end_pos": 43635736, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000147695.1", "url": "https://www.ensembl.org/id/ENSBTAT00000147695.1" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000105701.1", "url": "https://www.ensembl.org/id/ENSBTAP00000105701.1" } ] } }, { "isoform_ac": "F6RMD1-1", "url": "https://www.uniprot.org/uniprotkb/F6RMD1/entry", "sequence": { "sequence": "MLFVADPARPVTRGPRRKCGRRSPSRSPAGSWSRGLRLWRLLGLAAMATLWAGLLRLASMLSLSCLALSVLLLVQLSDAAKNSEDVRCKCICPPYKDNSGHIYNKNISQKDCDCLHVVDPMPVRGPDVEAYCLRCECKYEERSSVTIKVTIIIYLSILGLLLLYMVYLTLVEPILKRRLFGHSQLIQSDDDVGDHQPFANAHDVLARSRSRANVLNKVEYAQQRWKLQVQEQRKSVFDRHVVLS", "length": 244, "header": "tr|F6RMD1-1|F6RMD1_BOVIN Isoform 1 of TMEM9 domain family member B OS=Bos taurus OX=9913 GN=TMEM9B PE=3 SV=1 CANONICAL=F6RMD1-1" }, "locus": { "chromosome": "15", "start_pos": 43642669, "end_pos": 43625685, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000039850.5", "url": "https://www.ensembl.org/id/ENSBTAT00000039850.5" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000039636.3", "url": "https://www.ensembl.org/id/ENSBTAP00000039636.3" } ] } } ], "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "other", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 12, "start_aa": "Thr", "end_pos": 12, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr12", "evidence": [ { "id": "", "database": "GlyGen", "url": "https://data.glygen.org/" } ], "filter_code": "000000000000000010000.00000000001000.0.01000" } ], "phosphorylation": [], "glycation": [], "keywords": [ "glycoprotein", "glycoprotein_predicted" ], "publication": [], "pathway": [], "orthologs": [], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 2, "go_terms": [ { "name": "lysosomal membrane", "id": "GO:0005765", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005765", "evidence": [ { "database": "UniProtKB", "id": "F6RMD1", "url": "https://www.uniprot.org/uniprotkb/F6RMD1" } ], "pmid": "" }, { "name": "early endosome membrane", "id": "GO:0031901", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0031901", "evidence": [ { "database": "UniProtKB", "id": "F6RMD1", "url": "https://www.uniprot.org/uniprotkb/F6RMD1" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 106, "end_pos": 108, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [ 12 ], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 106, "end_pos": 108 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 1 }, { "field": "total_sites", "count": 1 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 1 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "exact_sites", "count": 1 }, { "field": "exact_o_linked_sites", "count": 1 }, { "field": "fuzzy_sites", "count": 0 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_pos", "start_aa", "end_pos", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 1 }, { "field": "total_sites", "count": 1 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 1 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "exact_sites", "count": 1 }, { "field": "exact_o_linked_sites", "count": 1 }, { "field": "fuzzy_sites", "count": 0 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_pos", "start_aa", "end_pos", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ], "tool_support": { "graph_view": "yes" } }, { "uniprot_canonical_ac": "F6RNG7-1", "uniprot_ac": "F6RNG7", "uniprot_id": "F6RNG7_BOVIN", "mass": { "chemical_mass": 46424.0, "monoisotopic_mass": 46424.0 }, "refseq": { "ac": "XP_005217165", "name": "glycosaminoglycan xylosylkinase isoform X1", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_005217165" }, "gene_names": [ { "name": "FAM20B", "type": "recommended", "evidence": [ { "id": "F6RNG7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F6RNG7" } ] }, { "name": "FAM20B", "type": "synonym", "evidence": [ { "id": "XP_005217165", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_005217165" } ] } ], "protein_names": [ { "name": "FAM20B glycosaminoglycan xylosylkinase", "type": "synonym", "evidence": [ { "id": "F6RNG7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F6RNG7/entry#names_and_taxonomy" } ] }, { "name": "glycosaminoglycan xylosylkinase isoform X1", "type": "synonym", "evidence": [ { "id": "XP_005217165", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_005217165" } ] } ], "function": [], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Bos taurus", "taxid": 9913, "evidence": [ { "database": "UniProtKB", "id": "F6RNG7", "url": "https://www.uniprot.org/uniprotkb/F6RNG7" } ], "common_name": "Bovine", "glygen_name": "Bovine", "reference_species": "Bos taurus [9913]" } ], "gene": [ { "name": "FAM20B", "url": "https://www.uniprot.org/uniprotkb/F6RNG7", "locus": { "chromosome": "16", "start_pos": 60417902, "end_pos": 60375473, "strand": "-", "evidence": [ { "database": "Ensembl Gene", "id": "ENSBTAG00000013999", "url": "https://www.ensembl.org/id/ENSBTAG00000013999" } ] } } ], "crossref": [ { "id": "F6RNG7", "url": "https://alphafold.ebi.ac.uk/entry/F6RNG7", "database": "AlphaFoldDB", "categories": [] }, { "id": "cd10470", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd10470", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "539755", "url": "https://www.ncbi.nlm.nih.gov/gene/539755", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR009581", "url": "https://www.ebi.ac.uk/interpro/entry/IPR009581", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR024869", "url": "https://www.ebi.ac.uk/interpro/entry/IPR024869", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "AVWEDDM", "url": "https://omabrowser.org/oma/group/AVWEDDM/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "PTHR12450", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR12450", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR12450:SF14", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR12450:SF14", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF06702", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF06702", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "XP_005217165", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_005217165", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "F6RNG7", "url": "https://www.uniprot.org/uniprotkb/F6RNG7", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "F6RNG7-1", "url": "https://www.uniprot.org/uniprotkb/F6RNG7-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MKLKQRVVLLAILLVIFIFTKVFLIDNLDTSAANREDQRAFHRMMAGLRVELVPKLDHTLQSPWEIAAQWVVPREVYPEETPELGAILHAMATKKIIKADVGYKGTQLKALLILEGGQKVVFKPKRYNRDYVVEGEPYAGYDRHNAEVAAFHLDRILGFRRAPLVVGRFVNLRTEIKPVATEQLLSTFLTVGNNTCFYGKCYYCRETEPACADGDTMEGSVTLWLPDVWPLQKHRHPWGRTYREGKLARWEYDESYCDAVKKTSPYDSGPRLLDIIDTAVFDYLIGNADRHHYESFQDDEGASMLILLDNAKSFGNPSLDERSILAPLYQCCIIRVSTWNRLNSLKNGVLKSALKSAMAHDPISPVLSDPHLDAVEQRLLSVLATVKQCTDQFGMDTVLVEDRMPLSHL", "length": 409, "header": "tr|F6RNG7-1|F6RNG7_BOVIN Isoform 1 of FAM20B glycosaminoglycan xylosylkinase OS=Bos taurus OX=9913 GN=FAM20B PE=3 SV=1 CANONICAL=F6RNG7-1" }, "isoforms": [ { "isoform_ac": "F6RNG7-1", "url": "https://www.uniprot.org/uniprotkb/F6RNG7/entry", "sequence": { "sequence": "MKLKQRVVLLAILLVIFIFTKVFLIDNLDTSAANREDQRAFHRMMAGLRVELVPKLDHTLQSPWEIAAQWVVPREVYPEETPELGAILHAMATKKIIKADVGYKGTQLKALLILEGGQKVVFKPKRYNRDYVVEGEPYAGYDRHNAEVAAFHLDRILGFRRAPLVVGRFVNLRTEIKPVATEQLLSTFLTVGNNTCFYGKCYYCRETEPACADGDTMEGSVTLWLPDVWPLQKHRHPWGRTYREGKLARWEYDESYCDAVKKTSPYDSGPRLLDIIDTAVFDYLIGNADRHHYESFQDDEGASMLILLDNAKSFGNPSLDERSILAPLYQCCIIRVSTWNRLNSLKNGVLKSALKSAMAHDPISPVLSDPHLDAVEQRLLSVLATVKQCTDQFGMDTVLVEDRMPLSHL", "length": 409, "header": "tr|F6RNG7-1|F6RNG7_BOVIN Isoform 1 of FAM20B glycosaminoglycan xylosylkinase OS=Bos taurus OX=9913 GN=FAM20B PE=3 SV=1 CANONICAL=F6RNG7-1" }, "locus": { "chromosome": "16", "start_pos": 60416898, "end_pos": 60388642, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000044368.6", "url": "https://www.ensembl.org/id/ENSBTAT00000044368.6" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000041871.4", "url": "https://www.ensembl.org/id/ENSBTAP00000041871.4" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [], "orthologs": [ { "uniprot_canonical_ac": "A0A9J7G0C5-1", "protein_name": "Glycosaminoglycan xylosylkinase isoform X1", "gene_name": "Fam20b", "tax_id": 10029, "organism": "Cricetulus griseus", "sequence": { "sequence": "MKLKQRVVLLAILLVIFIFTKVFLIDNLDTSAANREDQRAFHRMMSGLRVELVPKLDHTLQSPWEIAAQWVVPREVYPEETPELGAIMHAMATKKIIKADVGYKGTQLKALLILEGGQKVVFKPKRSPSGSGVQLNSHRYSRDYVVEGEPYAGYDRHNAEVAAFHLDRILGFRRAPLVVGRYVNLRTEIKPVATEQLLSTFLTVGNNTCFYGKCYYCRETEPACADGDMMEGSITLWLPDVWPLQKHRHPWGRTYREGKLARWEYDESYCDAVKKTSPYDSGPRLLDIIDTAVFDYLIGNADRHHYESFQDDEGASMLILLDNAKSFGNPSLDERSILAPLYQCCIIRVSTWNRLNYLKNGVLKSALKSAMAHDPISPVLSDPHLDTVDQRLLNVLATVKQCTDQFGMDTVLVEDRMPLSHL", "length": 422 }, "evidence": [ { "id": "F6RNG7", "url": "https://omabrowser.org/oma/group/F6RNG7/", "database": "OMA" } ], "glygen_name": "Hamster", "common_name": "Chinese hamster" }, { "uniprot_canonical_ac": "D3ZUZ4-1", "protein_name": "FAM20B, glycosaminoglycan xylosylkinase", "gene_name": "Fam20b", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MKLKQRVVVLAILLVIFIFTKVFLIDNLDTSAANREDQRAFHRMMTGLRVELVPKLDHTLQSPWEIAAQWVVPREVYPEETPELGAVMHAMATKKIIKADVGYKGTQLKALLTLEGGQKVVFKPKRYSRDYVVEGEPYAGYDRHNAEVAAFHLDRILGFRRAPLVVGRYVNLRTEVKPVATEQLLSTFLTVGNNTCFYGKCYYCRETEPACADGDMMEGSITLWLPDVWPLQKHRHPWGRTYREGKLARWEYDESYCDAVKKTSPYDSGPRLLDIIDTAVFDYLIGNADRHHYESFQDDEGASMLILLDNAKSFGNPSLDERSILAPLYQCCIIRVSTWNRLNYLKNGVLKSALKSAMAHDPIAPVLSDPHLDTVDQRLLNVLATIKQCTDQFGMDTVLVEDRMPLSHL", "length": 409 }, "evidence": [ { "id": "F6RNG7", "url": "https://omabrowser.org/oma/group/F6RNG7/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "F1NZJ0-1", "protein_name": "FAM20B, glycosaminoglycan xylosylkinase", "gene_name": "FAM20B", "tax_id": 9031, "organism": "Gallus gallus", "sequence": { "sequence": "MKLKQRVVLLAILLVIFIFTKVFLIDNLDTSAANREDQRAFHRMMASLRVELDPRLDHTLQSPWEIAAQWVVPREVYPEETPELGAVMHAMSTKKIIKADVGYKGTQLKALLILEGGQKVVFKPKRYARDYVVEGEPYAGYDRHNAEVAAFHLDRILGFRRAPLVVGRFVNLRTEIKPVATEQLLGTFMTVGNNTCFYGKCYYCRETEPACADGDIMEGSVTLWLPDVWPLQKHRHPWGRTYREGKLARWEYDESYCDAVKKTSPYDSGPRLLDIIDTAIFDYLIGNADRHHYESFQDDEGASMLILLDNAKSFGNPALDERSILAPLYQCCIIRVSTWNRLNYLKNGVLKSALKTAMSHDPISPVLSDPHLDALDQRLLSILATVKQCTDQFGPDVVLVEDRMTLSHL", "length": 409 }, "evidence": [ { "id": "F6RNG7", "url": "https://omabrowser.org/oma/group/F6RNG7/", "database": "OMA" } ], "glygen_name": "Chicken", "common_name": "Chicken" }, { "uniprot_canonical_ac": "F1S6Y3-1", "protein_name": "FAM20B glycosaminoglycan xylosylkinase", "gene_name": "FAM20B", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MKLKQRVVLLAILLVIFIFTKVFLIDNLDTSAANREDQRAFHRMMAGLRVELVPKLDHTLQSPWEIAAQWVVPREVYPEETPELGAIMHAMATKKIIKADVGYKGTQLKALLILEGGQKVVFKPKRYNRDYVVEGEPYAGYDRHNAEVAAFHLDRILGFRRAPLVVGRFVNLRTEIKPVATEQLLSTFLTVGNNTCFYGKCYYCRETEPACADGDTMEGSVTLWLPDVWPLQKHRHPWGRTYREGKLARWEYDESYCDAVKKTSPYDSGPRLLDIIDTAVFDYLIGNADRHHYESFQDDEGASMLILLDNAKSFGNPSLDERSILAPLYQCCIIRVSTWNRLNSLKNGVLKSALKSAMAHDPISPVLSDPHLDALDQRLLSVLATVKQCTDQFGMDTVLVEDRMPLSHL", "length": 409 }, "evidence": [ { "id": "F6RNG7", "url": "https://omabrowser.org/oma/group/F6RNG7/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "O75063-1", "protein_name": "Glycosaminoglycan xylosylkinase", "gene_name": "FAM20B", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MKLKQRVVLLAILLVIFIFTKVFLIDNLDTSAANREDQRAFHRMMTGLRVELAPKLDHTLQSPWEIAAQWVVPREVYPEETPELGAVMHAMATKKIIKADVGYKGTQLKALLILEGGQKVVFKPKRYSRDHVVEGEPYAGYDRHNAEVAAFHLDRILGFHRAPLVVGRFVNLRTEIKPVATEQLLSTFLTVGNNTCFYGKCYYCRETEPACADGDIMEGSVTLWLPDVWPLQKHRHPWGRTYREGKLARWEYDESYCDAVKKTSPYDSGPRLLDIIDTAVFDYLIGNADRHHYESFQDDEGASMLILLDNAKSFGNPSLDERSILAPLYQCCIIRVSTWNRLNYLKNGVLKSALKSAMAHDPISPVLSDPHLDAVDQRLLSVLATVKQCTDQFGMDTVLVEDRMPLSHL", "length": 409 }, "evidence": [ { "id": "F6RNG7", "url": "https://omabrowser.org/oma/group/F6RNG7/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "Q5RH51-1", "protein_name": "Glycosaminoglycan xylosylkinase", "gene_name": "fam20b", "tax_id": 7955, "organism": "Danio rerio", "sequence": { "sequence": "MKLKQRVVVLCAVLFLLGLAKVFLLDGGEGSAASRRDLRAFRKMEASLSLAKGARLTHTLQSPWEVAAQWVGPREVYPDETPELAAVLNALATAHVERADVGYKGTQLKALLVLDGGQKVVFKPKRYVRDYVVEGEPYAGYDRHNAEIAAFHLDRILGFRRAPLVVGRFMNLRTEIKPVATDQLLSTFLMHGNNTCFYGKCYYCRETEPACAEGDVMEGSVTLWLPDVWPLQKHRHPWGRTYREGKLARWEYDESYCEAVKKMPPYDAGPRLLDVIDTSIFDYLIGNADRHHYESFQDDGGASMLILLDNAKSFGNPSLDERSILAPLYQCCMVRVSTWNRLNLLKGGVLSSAMRQATAHDPAFPVLTGAHLTALDRRLNGVLATVRQCMETQGSENTLIEDRMNLPHP", "length": 409 }, "evidence": [ { "id": "F6RNG7", "url": "https://omabrowser.org/oma/group/F6RNG7/", "database": "OMA" } ], "glygen_name": "Zebrafish", "common_name": "Zebrafish" }, { "uniprot_canonical_ac": "Q8VCS3-1", "protein_name": "Glycosaminoglycan xylosylkinase", "gene_name": "Fam20b", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MKLKQRVVLLAILLVIFIFTKVFLIDNLDTSAANREDQRAFHRMMTGLRVELVPKLDHTLQSPWEIAAQWVVPREVYPEETPELGAIMHAMATKKIIKADVGYKGTQLKALLILEGGQKVVFKPKRYSRDYVVEGEPYAGYDRHNAEVAAFHLDRILGFRRAPLVVGRYVNLRTEVKPVATEQLLSTFLTVGNNTCFYGKCYYCRETEPACADGDMMEGSVTLWLPDVWPLQKHRHPWGRTYREGKLARWEYDESYCDAVKKTSPYDSGPRLLDIIDTAVFDYLIGNADRHHYESFQDDEGASMLILLDNAKSFGNPSLDERSILAPLYQCCIIRVSTWNRLNYLKNGVLKSALKSAMAHDPISPVLSDPHLDTVDQRLLNVLATIKQCTDQFGTDTVLVEDRMPLSHL", "length": 409 }, "evidence": [ { "id": "F6RNG7", "url": "https://omabrowser.org/oma/group/F6RNG7/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q95T10-1", "protein_name": "Glycosaminoglycan xylosylkinase homolog", "gene_name": "", "tax_id": 7227, "organism": "Drosophila melanogaster", "sequence": { "sequence": "MNKRSVIIAGIVASLLGLALGANFYFMYYLSAEEGHLASVRALENMIRHKMRHLKPNYLNRNPRFFMFRNKLLKNYKAAPYENASVLWDIANWWPHENEVYPLYDSSMGQLLETLRREPITRVSNLGRGTQLKLLVRLSHQQKVIFKPQWYPREEVIDGMIYSGKDRHTAEVYAFYLGAVLDFRWTPIVVGRVVNLKKEIYAKGDPELQQTINIETDEDGREKYCLFGKCHYCNEEETVCGDERHNIEGVLIYIVPGTLAKRRSPWQRTYKDDKRAPWEDDMTYCKSLKNKMETIRLLDLIDASIFDYLIQNGDRHHYETREERVVLIDNGKAFGNPNKDHLDILAPLYQCCLLRKSTWDRLQVFSGGVLTEIIDRLSKQDALYPLITDKHKKGVERRLLVVYAVVEHCMDIEGDKMFKTL", "length": 421 }, "evidence": [ { "id": "F6RNG7", "url": "https://omabrowser.org/oma/group/F6RNG7/", "database": "OMA" } ], "glygen_name": "Fruit fly", "common_name": "Fruit fly" } ], "go_annotation": { "categories": [ { "name": "Molecular Function", "total": 3, "go_terms": [ { "name": "ATP binding", "id": "GO:0005524", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005524", "evidence": [ { "database": "UniProtKB", "id": "F6RNG7", "url": "https://www.uniprot.org/uniprotkb/F6RNG7" } ], "pmid": "" }, { "name": "metal ion binding", "id": "GO:0046872", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0046872", "evidence": [ { "database": "UniProtKB", "id": "F6RNG7", "url": "https://www.uniprot.org/uniprotkb/F6RNG7" } ], "pmid": "" }, { "name": "phosphotransferase activity, alcohol group as acceptor", "id": "GO:0016773", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016773", "evidence": [ { "database": "UniProtKB", "id": "F6RNG7", "url": "https://www.uniprot.org/uniprotkb/F6RNG7" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 1, "go_terms": [ { "name": "Golgi apparatus", "id": "GO:0005794", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005794", "evidence": [ { "database": "UniProtKB", "id": "F6RNG7", "url": "https://www.uniprot.org/uniprotkb/F6RNG7" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 193, "end_pos": 195, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "F6RNG7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F6RNG7" }, { "id": "PF06702", "database": "Pfam", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF06702" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "FAM20 C-terminal", "eco_id": "ECO_0000259", "start_pos": 191, "end_pos": 398, "start_aa": "Val", "end_aa": "Val", "glycosite_overlap": [] } ], "binding_sites": [ { "evidence": [ { "id": "F6RNG7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F6RNG7" }, { "id": "PIRSR624869-3", "database": "PIR Site Rule", "url": "https://proteininformationresource.org/cgi-bin/pirrule?id=PIRSR624869-3" } ], "binding_site_uniprot": 142, "amino_acid": "Asp", "chebi_lig_id": "CHEBI:29035", "ligand": "Mn(2+)", "ligand_label": "", "uniprotkb_ligand_comment": "", "eco_id": "ECO_0000256", "start_pos": 142, "end_pos": 142, "start_aa": "Asp", "end_aa": "Asp", "glycosite_overlap": [] }, { "evidence": [ { "id": "F6RNG7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F6RNG7" }, { "id": "PIRSR624869-3", "database": "PIR Site Rule", "url": "https://proteininformationresource.org/cgi-bin/pirrule?id=PIRSR624869-3" } ], "binding_site_uniprot": 309, "amino_acid": "Asp", "chebi_lig_id": "CHEBI:29035", "ligand": "Mn(2+)", "ligand_label": "", "uniprotkb_ligand_comment": "", "eco_id": "ECO_0000256", "start_pos": 309, "end_pos": 309, "start_aa": "Asp", "end_aa": "Asp", "glycosite_overlap": [] } ], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "homologset.oma", "label": "OMA Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 193, "end_pos": 195 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ], "tool_support": { "graph_view": "yes" } }, { "uniprot_canonical_ac": "F6RNH4-1", "uniprot_ac": "F6RNH4", "uniprot_id": "F6RNH4_BOVIN", "mass": { "chemical_mass": 99122.0, "monoisotopic_mass": 99122.0 }, "refseq": {}, "gene_names": [ { "name": "PPP1R13L", "type": "recommended", "evidence": [ { "id": "F6RNH4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F6RNH4" } ] } ], "protein_names": [ { "name": "Protein phosphatase 1 regulatory subunit 13 like", "type": "synonym", "evidence": [ { "id": "F6RNH4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F6RNH4/entry#names_and_taxonomy" } ] } ], "function": [], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Bos taurus", "taxid": 9913, "evidence": [ { "database": "UniProtKB", "id": "F6RNH4", "url": "https://www.uniprot.org/uniprotkb/F6RNH4" } ], "common_name": "Bovine", "glygen_name": "Bovine", "reference_species": "Bos taurus [9913]" } ], "gene": [ { "name": "PPP1R13L", "url": "https://www.uniprot.org/uniprotkb/F6RNH4", "locus": { "chromosome": "18", "start_pos": 53005632, "end_pos": 53020786, "strand": "+", "evidence": [ { "database": "Ensembl Gene", "id": "ENSBTAG00000020689", "url": "https://www.ensembl.org/id/ENSBTAG00000020689" } ] } } ], "crossref": [ { "id": "F6RNH4", "url": "https://alphafold.ebi.ac.uk/entry/F6RNH4", "database": "AlphaFoldDB", "categories": [] }, { "id": "cd11952", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd11952", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "IPR001452", "url": "https://www.ebi.ac.uk/interpro/entry/IPR001452", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR002110", "url": "https://www.ebi.ac.uk/interpro/entry/IPR002110", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR028320", "url": "https://www.ebi.ac.uk/interpro/entry/IPR028320", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR036028", "url": "https://www.ebi.ac.uk/interpro/entry/IPR036028", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR036770", "url": "https://www.ebi.ac.uk/interpro/entry/IPR036770", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR042722", "url": "https://www.ebi.ac.uk/interpro/entry/IPR042722", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "QPNQYKH", "url": "https://omabrowser.org/oma/group/QPNQYKH/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "PTHR24164", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR24164", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR24164:SF4", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR24164:SF4", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF12796", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF12796", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF14604", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF14604", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "F6RNH4", "url": "https://www.uniprot.org/uniprotkb/F6RNH4", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "F6RNH4-1", "url": "https://www.uniprot.org/uniprotkb/F6RNH4-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MDFMSVRMGTYPAMSRSSGTTSPKVLEATPYSPSPPRPASLWSESRRLTCSRRLPRPVLGSPQPEPEPEEAPRCQSLPRICAPLRPAGTMDSEAFQSSGDILDLKFQSLAMKHMDLKQMELDTAAAKVDELTKQLESLWSDSPAAPLGSQAAAPARLPRYSTSPVPEPLGSRGSSRKATTDGADTPFGRSESAPALLPYSSLSAKGRPSSPRTQLYLQPDAYGSLDRSPSPRPRAFDGAGSPHGRAPSPRPGPLRQQGPPTHFDFLGRSGSPRGSPLAEGPQAFFPERGPSPRPGTSAYDAPAAFGSPLLGAGGSAFAPPLRAQDDLTLRRRPPKAWNESDLDVAYEKKPSQTASYERLDVFPRPASPGLQLLPWRESSLDGLGATGKDNFTSATLPRNYKVSPLANDRRSDVGSYRRSLGSTGPSGTLPRSWQPVSRIPMPPSSPQPRSAPRQRPIPLSMIFKLQNAFWEHGASRAMLPSSSIFSRAPPPKMPPQPQTPPQPQPQPQPQLPPQPQPQLQPQPQPQAPAPAPQAPQQTWAPVSEGLAKPPADLEPEPELEGLLTPVLEVGDADEGAVTRPLSPTRLQPALPPEAQSVPELEEVARVLAEIPRPLKRRGSMEQSPAVALPPTHKKQYQQIISRLFHRHGGPGGPEPELSPITEGSEARAGPPAPAPPAPIPPSTPLQSSPPEQPQSMEMRSVLRKAGSPRKVRRARLNPLVLLLDAALTGELEVVQQAMKEMNDPSQPNEEGITALHNAICGANYPIVDFLIAAGANVNSPDSHGWTPLHCAASCNDTAICTALVQHGAAIFATTLSDGATAIEKCDPYREGYADCATYLADVEQSMGLMYNGVVYALWDYSAEFGDELSFREGDSVTVLRRDGLEETDWWWATLHGQEGYVPRNYFGLFPRVKPQRSKV", "length": 919, "header": "tr|F6RNH4-1|F6RNH4_BOVIN Isoform 1 of Protein phosphatase 1 regulatory subunit 13 like OS=Bos taurus OX=9913 GN=PPP1R13L PE=1 SV=1 CANONICAL=F6RNH4-1" }, "isoforms": [ { "isoform_ac": "F6RNH4-1", "url": "https://www.uniprot.org/uniprotkb/F6RNH4/entry", "sequence": { "sequence": "MDFMSVRMGTYPAMSRSSGTTSPKVLEATPYSPSPPRPASLWSESRRLTCSRRLPRPVLGSPQPEPEPEEAPRCQSLPRICAPLRPAGTMDSEAFQSSGDILDLKFQSLAMKHMDLKQMELDTAAAKVDELTKQLESLWSDSPAAPLGSQAAAPARLPRYSTSPVPEPLGSRGSSRKATTDGADTPFGRSESAPALLPYSSLSAKGRPSSPRTQLYLQPDAYGSLDRSPSPRPRAFDGAGSPHGRAPSPRPGPLRQQGPPTHFDFLGRSGSPRGSPLAEGPQAFFPERGPSPRPGTSAYDAPAAFGSPLLGAGGSAFAPPLRAQDDLTLRRRPPKAWNESDLDVAYEKKPSQTASYERLDVFPRPASPGLQLLPWRESSLDGLGATGKDNFTSATLPRNYKVSPLANDRRSDVGSYRRSLGSTGPSGTLPRSWQPVSRIPMPPSSPQPRSAPRQRPIPLSMIFKLQNAFWEHGASRAMLPSSSIFSRAPPPKMPPQPQTPPQPQPQPQPQLPPQPQPQLQPQPQPQAPAPAPQAPQQTWAPVSEGLAKPPADLEPEPELEGLLTPVLEVGDADEGAVTRPLSPTRLQPALPPEAQSVPELEEVARVLAEIPRPLKRRGSMEQSPAVALPPTHKKQYQQIISRLFHRHGGPGGPEPELSPITEGSEARAGPPAPAPPAPIPPSTPLQSSPPEQPQSMEMRSVLRKAGSPRKVRRARLNPLVLLLDAALTGELEVVQQAMKEMNDPSQPNEEGITALHNAICGANYPIVDFLIAAGANVNSPDSHGWTPLHCAASCNDTAICTALVQHGAAIFATTLSDGATAIEKCDPYREGYADCATYLADVEQSMGLMYNGVVYALWDYSAEFGDELSFREGDSVTVLRRDGLEETDWWWATLHGQEGYVPRNYFGLFPRVKPQRSKV", "length": 919, "header": "tr|F6RNH4-1|F6RNH4_BOVIN Isoform 1 of Protein phosphatase 1 regulatory subunit 13 like OS=Bos taurus OX=9913 GN=PPP1R13L PE=1 SV=1 CANONICAL=F6RNH4-1" }, "locus": { "chromosome": "18", "start_pos": 53020587, "end_pos": 53006184, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000027570.7", "url": "https://www.ensembl.org/id/ENSBTAT00000027570.7" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000027570.6", "url": "https://www.ensembl.org/id/ENSBTAP00000027570.6" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [], "orthologs": [ { "uniprot_canonical_ac": "F1LW07-1", "protein_name": "Protein phosphatase 1, regulatory subunit 13 like", "gene_name": "Ppp1r13l", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MISPSAQRHPAPAGTMDSEAFQQARDLLDLNFQSLAMKHMDLKQMELDTAAAKVDELTKQLESLWSDSPAPPGTQAGVPSRMSRYSTSPVPEHFGSRGSLQKIAADGVEARFGRSESAPSLHPYSPLSPKGRPSSPRTSIYLQPTTPDPYSSLDRAPSPRPRAFEGTGSPHGRAPSPRPGTGPVRQPGPPTPFDYLGRAGSPRGSPLAEGPQAFFPERGPSPRPPAAAYDTSATFGSPLLGAGGSAFAPPLRAQDDSTLRRRPPKAWNESDLDVAYEKKSSQTASYERLDVFTRPASPGLQLLPWRESSLDGLGASGKDNITSATLPRNYKVSPLASDRRSDVGSYRRSMGSAGPSGTLPRSWQPVSRIPMPPSSPQPRSTPRQRPIPLSMIFKLQNAFWEHGASRAVLPGSPIFSRAPPPKLPPQPPPQPQLPPQPQPQMPPQSQPQPQTPVPQQTWSPMNEGLLKSPAELEPEPELEGLLAPVLESGDADEGTVTRPLSPTRLQPALPPEAQTVPELEEVARVLAEIPRPLKRRGSMEQSPAAALPPTHKKQYQQIINRLFHRHGGPGPGGPEPELSTITEGSEARAGPPAPAPPAPIPPPAPAQSNPPEQPQSMEMRSVLRKVGSPRKARRARLNPLVLLLDAALTGELDVVQQAVKEMNDPSQPNEEGITALHNAICGANYPIVDFLIAAGANVNSPDSHGWTPLHCAASCNDTAICTALVQHGAAIFATTLSDGATAIEKCDPYREGYADCATYLADVEQSMGLMHNGVVYALWDYSAEFGDELSFREGESVTVLRRDGPEETDWWWAALHGQEGYVPRNYFGLFPRVKSQRSKI", "length": 840 }, "evidence": [ { "id": "F6RNH4", "url": "https://omabrowser.org/oma/group/F6RNH4/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "Q1L9A3-1", "protein_name": "RelA-associated inhibitor isoform X1", "gene_name": "ppp1r13l", "tax_id": 7955, "organism": "Danio rerio", "sequence": { "sequence": "MNSQGGFGSNLMFQSINNELNASLATADELSREFSSLLTEAAPVVQTSTAQISSPRAQISNDGSSNSFNNNGNESSKTSFTQSPTSVFSSDPINSRKESNLNQNPSPQLIRESMKYMPSSPSPLTQQHSPFATRKDYSDSRYTFDQNMSPNTVRRTQMPLRPQDRSTRGSMSYGEMSSPTYDSKTSRSSPQAPSSPLFSAPRSPRLDRPPSSQPFSQQAASTLPRNFRHPEEGMQRPKNSSKWNESDLDASYERKHHHTYDKNEWVRPPVPNSNWKESSLDAPTPAKKETVTQSFPPYHHSSLPRNARISVPPDLSSGSSTPYSNPSISSRISVPPVSSGAPRHRPIPLSVILRLQNPHYYPEAVNRYVPGPIGEPQQGVYHHLPLPQDYMWQNQTPQRQQTQKHPAYYGEVLHPTEVDAELEKLDSSKTVGPVSLIDQGMKPEEESKVEDPEIPRPLSPTRLQPVMAPQADLDTDLDELMRIRAEFPRALKKRSSLDVSQPLPNIPVSQPNYYKQIINKMFRRTAVRIREEPAAENSSSSDGEESSKSPISVVPVRVTETISSEQKGVHSILRKGKKANKSASRRAHLSPLILMLDGALVGELETVQRAAQKMSDPSQSNDEGITALHNAICGGHFPVVEFLVRIGANVSAPDSHGWTPLHCAASCNDRQMSEFLVRNGAAVMAITDSDGATASQKCDPYAPGYEECESLLRGVEEAMGVENSGVVYALWGYPAQAPDELSFKEGDMVTILQKPEGEGWWWASLCGREGFVPNNYFGLFPKVRPKTLC", "length": 789 }, "evidence": [ { "id": "F6RNH4", "url": "https://omabrowser.org/oma/group/F6RNH4/", "database": "OMA" } ], "glygen_name": "Zebrafish", "common_name": "Zebrafish" }, { "uniprot_canonical_ac": "Q5I1X5-1", "protein_name": "RelA-associated inhibitor", "gene_name": "Ppp1r13l", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MDSEAFQHARDLLDLNFQSLAMKHMDLKQMELDTAAAKVDELTKQLESLWSDSPAPPGAQAGVPSRMARYSTSPVPEHFGSRGSPQKIATDGIEARFGRSESAPSLHPYSPLSPKGRPSSPRTPIYLQPDTYSSLDRAPSPRPRAFDGAGSPHGRAPSPRPGIGPVRQPGPSTPFDYLGRAGSPRGSPLAEGPQAFFPERGPSPRPPAAAYDTAGTFGSPLLGAGGSAFTPPLRAQDDSTLRRRPPKAWNESDLDVAYEKKSSQTASYERLDVFTRPASPGLQLLPWRESSLDGLGASGKDHLTSATLPRNYKVSPLASDRRSDVGSYRRSLGSAGPSGTLPRSWQPVSRIPMPPSSPQPRSTPRQRPIPLSMIFKLQNAFWEHGAGRAVLPGSPIFSRAPPPKLPPQPPPQPQMQPQPQPQPQMQPQSQAQPQTPAPQQTWSPMNEGLLKSPAELEPEPELEVLLAPVEEAGDADEGTVTRPLSPTRLQPALPPEAQTVPELEEVARVLAEIPRPLKRRGSMEQSPAVALPPTHKKQYQQIINRLFHRHGGPGPGGPEPELSTITEGSEARAGPPAPAPPAPIPPPAPPQSSPPEQPQSMEMRSVLRKVGSPRKARRARLNPLVLLLDAALTGELDVVQQAVKEMNDPSQPNEEGITALHNAICGANYPIVDFLIAAGANVNSPDSHGWTPLHCAASCNDTAICTALVQHGAAIFATTLSDGATAIEKCDPYREGYADCATYLADVEQSMGLMHNGVVYALWDYSAEFGDELSFREGESVTVLRRDGPEETDWWWASLHGQEGYVPRNYFGLFPRVKSQRSKI", "length": 824 }, "evidence": [ { "id": "F6RNH4", "url": "https://omabrowser.org/oma/group/F6RNH4/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q8WUF5-1", "protein_name": "RelA-associated inhibitor", "gene_name": "PPP1R13L", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MDSEAFQSARDFLDMNFQSLAMKHMDLKQMELDTAAAKVDELTKQLESLWSDSPAPPGPQAGPPSRPPRYSSSSIPEPFGSRGSPRKAATDGADTPFGRSESAPTLHPYSPLSPKGRPSSPRTPLYLQPDAYGSLDRATSPRPRAFDGAGSSLGRAPSPRPGPGPLRQQGPPTPFDFLGRAGSPRGSPLAEGPQAFFPERGPSPRPPATAYDAPASAFGSSLLGSGGSAFAPPLRAQDDLTLRRRPPKAWNESDLDVAYEKKPSQTASYERLDVFARPASPSLQLLPWRESSLDGLGGTGKDNLTSATLPRNYKVSPLASDRRSDAGSYRRSLGSAGPSGTLPRSWQPVSRIPMPPSSPQPRGAPRQRPIPLSMIFKLQNAFWEHGASRAMLPGSPLFTRAPPPKLQPQPQPQPQPQSQPQPQLPPQPQTQPQTPTPAPQHPQQTWPPVNEGPPKPPTELEPEPEIEGLLTPVLEAGDVDEGPVARPLSPTRLQPALPPEAQSVPELEEVARVLAEIPRPLKRRGSMEQAPAVALPPTHKKQYQQIISRLFHRHGGPGPGGPEPELSPITEGSEARAGPPAPAPPAPIPPPAPSQSSPPEQPQSMEMRSVLRKAGSPRKARRARLNPLVLLLDAALTGELEVVQQAVKEMNDPSQPNEEGITALHNAICGANYSIVDFLITAGANVNSPDSHGWTPLHCAASCNDTVICMALVQHGAAIFATTLSDGATAFEKCDPYREGYADCATYLADVEQSMGLMNSGAVYALWDYSAEFGDELSFREGESVTVLRRDGPEETDWWWAALHGQEGYVPRNYFGLFPRVKPQRSKV", "length": 828 }, "evidence": [ { "id": "F6RNH4", "url": "https://omabrowser.org/oma/group/F6RNH4/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" } ], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 2, "go_terms": [ { "name": "nucleus", "id": "GO:0005634", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005634", "evidence": [ { "database": "UniProtKB", "id": "F6RNH4", "url": "https://www.uniprot.org/uniprotkb/F6RNH4" } ], "pmid": "" }, { "name": "cytosol", "id": "GO:0005829", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005829", "evidence": [ { "database": "UniProtKB", "id": "F6RNH4", "url": "https://www.uniprot.org/uniprotkb/F6RNH4" } ], "pmid": "" } ] }, { "name": "Molecular Function", "total": 1, "go_terms": [ { "name": "identical protein binding", "id": "GO:0042802", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0042802", "evidence": [ { "database": "UniProtKB", "id": "F6RNH4", "url": "https://www.uniprot.org/uniprotkb/F6RNH4" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 3, "go_terms": [ { "name": "regulation of DNA-templated transcription", "id": "GO:0006355", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006355", "evidence": [ { "database": "UniProtKB", "id": "F6RNH4", "url": "https://www.uniprot.org/uniprotkb/F6RNH4" } ], "pmid": "" }, { "name": "apoptotic process", "id": "GO:0006915", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006915", "evidence": [ { "database": "UniProtKB", "id": "F6RNH4", "url": "https://www.uniprot.org/uniprotkb/F6RNH4" } ], "pmid": "" }, { "name": "negative regulation of inflammatory response", "id": "GO:0050728", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0050728", "evidence": [ { "database": "UniProtKB", "id": "F6RNH4", "url": "https://www.uniprot.org/uniprotkb/F6RNH4" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 338, "end_pos": 340, "annotation": "n_glycosylation_sequon" }, { "start_pos": 390, "end_pos": 392, "annotation": "n_glycosylation_sequon" }, { "start_pos": 795, "end_pos": 797, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "F6RNH4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F6RNH4" }, { "id": "PS50002", "database": "PROSITE", "url": "https://prosite.expasy.org/PS50002" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "SH3", "eco_id": "ECO_0000259", "start_pos": 849, "end_pos": 911, "start_aa": "Met", "end_aa": "Arg", "glycosite_overlap": [] } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "homologset.oma", "label": "OMA Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 338, "end_pos": 340 }, { "start_pos": 390, "end_pos": 392 }, { "start_pos": 795, "end_pos": 797 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ], "tool_support": { "graph_view": "yes" } }, { "uniprot_canonical_ac": "F6RP24-1", "uniprot_ac": "F6RP24", "uniprot_id": "F6RP24_BOVIN", "mass": { "chemical_mass": 22431.0, "monoisotopic_mass": 22431.0 }, "refseq": {}, "gene_names": [ { "name": "MS4A5", "type": "recommended", "evidence": [ { "id": "F6RP24", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F6RP24" } ] } ], "protein_names": [ { "name": "Membrane spanning 4-domains A5", "type": "synonym", "evidence": [ { "id": "F6RP24", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F6RP24/entry#names_and_taxonomy" } ] } ], "function": [], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Bos taurus", "taxid": 9913, "evidence": [ { "database": "UniProtKB", "id": "F6RP24", "url": "https://www.uniprot.org/uniprotkb/F6RP24" } ], "common_name": "Bovine", "glygen_name": "Bovine", "reference_species": "Bos taurus [9913]" } ], "gene": [ { "name": "MS4A5", "url": "https://www.uniprot.org/uniprotkb/F6RP24", "locus": { "chromosome": "15", "start_pos": 83278952, "end_pos": 83251879, "strand": "-", "evidence": [ { "database": "Ensembl Gene", "id": "ENSBTAG00000004583", "url": "https://www.ensembl.org/id/ENSBTAG00000004583" } ] } } ], "crossref": [ { "id": "F6RP24", "url": "https://alphafold.ebi.ac.uk/entry/F6RP24", "database": "AlphaFoldDB", "categories": [] }, { "id": "ENSBTAG00000004583", "url": "https://bgee.org/?page=gene&gene_id=ENSBTAG00000004583", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "777599", "url": "https://www.ncbi.nlm.nih.gov/gene/777599", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR007237", "url": "https://www.ebi.ac.uk/interpro/entry/IPR007237", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR030417", "url": "https://www.ebi.ac.uk/interpro/entry/IPR030417", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "LFGVMNF", "url": "https://omabrowser.org/oma/group/LFGVMNF/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "F6RP24", "url": "https://www.orthodb.org/?gene=F6RP24", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR23320", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR23320", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR23320:SF54", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR23320:SF54", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF04103", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF04103", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "A0ABI0P389", "url": "https://www.uniprot.org/uniprotkb/A0ABI0P389", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0ABI0P389-1", "url": "https://www.uniprot.org/uniprotkb/A0ABI0P389-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "F6RP24", "url": "https://www.uniprot.org/uniprotkb/F6RP24", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "F6RP24-1", "url": "https://www.uniprot.org/uniprotkb/F6RP24-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MDSRAAHSPVFLVFPPDITMPEFQSGDITGTTYDSSMPFPKLLATRMKILGAVQILFGVMNFSFGTVLLFTLEDPYPRFPFIFISGYPFWSSILFVNSGAFLVALERKTTETLVTLSRIMNSLSAVAAAAGIILLIIGFLIDRDFLCGYSGEVSECHAVTTLFIGILIMLMAFSIIEFLISLSFSVMRGPTECGDCEEWDGAEL", "length": 204, "header": "tr|F6RP24-1|F6RP24_BOVIN Isoform 1 of Membrane spanning 4-domains A5 OS=Bos taurus OX=9913 GN=MS4A5 PE=3 SV=1 CANONICAL=F6RP24-1" }, "isoforms": [ { "isoform_ac": "A0ABI0P389-1", "url": "https://www.uniprot.org/uniprotkb/A0ABI0P389/entry", "sequence": { "sequence": "MDSRAAHSPVFLVFPPDITMPEFQSGDITGTTYDSSMPFPKLLATRMKILGAVQILFGVMNFSFGTVLLFTLEDPYPRFPFIFISGYPFWSSILVTLSRIMNSLSAVAAAAGIILLIIGFLIDRDFLCGYSGEVSECHAVTTLFIGILIMLMAFSIIEFLISLSFSVMRGPTECGDCEEWDGAEL", "length": 185, "header": "tr|A0ABI0P389-1|A0ABI0P389_BOVIN Computationally mapped isoform of Membrane spanning 4-domains A5 OS=Bos taurus OX=9913 GN=MS4A5 PE=3 SV=1 CANONICAL=F6RP24-1" }, "locus": { "chromosome": "15", "start_pos": 83278932, "end_pos": 83251978, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000138407.1", "url": "https://www.ensembl.org/id/ENSBTAT00000138407.1" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000107404.1", "url": "https://www.ensembl.org/id/ENSBTAP00000107404.1" } ] } }, { "isoform_ac": "F6RP24-1", "url": "https://www.uniprot.org/uniprotkb/F6RP24/entry", "sequence": { "sequence": "MDSRAAHSPVFLVFPPDITMPEFQSGDITGTTYDSSMPFPKLLATRMKILGAVQILFGVMNFSFGTVLLFTLEDPYPRFPFIFISGYPFWSSILFVNSGAFLVALERKTTETLVTLSRIMNSLSAVAAAAGIILLIIGFLIDRDFLCGYSGEVSECHAVTTLFIGILIMLMAFSIIEFLISLSFSVMRGPTECGDCEEWDGAEL", "length": 204, "header": "tr|F6RP24-1|F6RP24_BOVIN Isoform 1 of Membrane spanning 4-domains A5 OS=Bos taurus OX=9913 GN=MS4A5 PE=3 SV=1 CANONICAL=F6RP24-1" }, "locus": { "chromosome": "15", "start_pos": 83278932, "end_pos": 83251978, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000006015.5", "url": "https://www.ensembl.org/id/ENSBTAT00000006015.5" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000006015.4", "url": "https://www.ensembl.org/id/ENSBTAP00000006015.4" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [], "orthologs": [ { "uniprot_canonical_ac": "M0R8A0-1", "protein_name": "Membrane spanning 4-domains A5", "gene_name": "Ms4a5", "tax_id": 10116, "organism": "Rattus 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Component", "total": 2, "go_terms": [ { "name": "plasma membrane", "id": "GO:0005886", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005886", "evidence": [ { "database": "UniProtKB", "id": "F6RP24", "url": "https://www.uniprot.org/uniprotkb/F6RP24" } ], "pmid": "" }, { "name": "membrane", "id": "GO:0016020", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016020", "evidence": [ { "database": "UniProtKB", "id": "F6RP24", "url": "https://www.uniprot.org/uniprotkb/F6RP24" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 1, "go_terms": [ { "name": "cell surface receptor signaling pathway", "id": "GO:0007166", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007166", "evidence": [ { "database": "UniProtKB", "id": "F6RP24", "url": "https://www.uniprot.org/uniprotkb/F6RP24" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 61, "end_pos": 63, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], 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"uniprot_ac": "F6RP65", "uniprot_id": "F6RP65_BOVIN", "mass": { "chemical_mass": 19823.0, "monoisotopic_mass": 19823.0 }, "refseq": {}, "gene_names": [ { "name": "LOC511175", "type": "recommended", "evidence": [ { "id": "F6RP65", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F6RP65" } ] } ], "protein_names": [ { "name": "Uncharacterized protein", "type": "synonym", "evidence": [ { "id": "F6RP65", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F6RP65/entry#names_and_taxonomy" } ] } ], "function": [], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Bos taurus", "taxid": 9913, "evidence": [ { "database": "UniProtKB", "id": "F6RP65", "url": "https://www.uniprot.org/uniprotkb/F6RP65" } ], "common_name": "Bovine", "glygen_name": "Bovine", "reference_species": "Bos taurus [9913]" } ], "gene": [ { "name": "LOC511175", "url": "https://www.uniprot.org/uniprotkb/F6RP65", "locus": {} } ], "crossref": [ { "id": "F6RP65", "url": "https://alphafold.ebi.ac.uk/entry/F6RP65", "database": "AlphaFoldDB", "categories": [] }, { "id": "ENSBTAG00000039384", "url": "https://bgee.org/?page=gene&gene_id=ENSBTAG00000039384", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "IPR006597", "url": "https://www.ebi.ac.uk/interpro/entry/IPR006597", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR011990", "url": "https://www.ebi.ac.uk/interpro/entry/IPR011990", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "KNEDMAM", "url": "https://omabrowser.org/oma/group/KNEDMAM/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "F6RP65", "url": "https://www.orthodb.org/?gene=F6RP65", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PF08238", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF08238", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "F6RP65", "url": "https://www.uniprot.org/uniprotkb/F6RP65", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "F6RP65-1", "url": "https://www.uniprot.org/uniprotkb/F6RP65-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MTPLMPHNQKRRSQASDTHALGTILPQKYKAHARDSWSTWELLVISGSMVSLLYIWLYSQSFHFHVAHLYAHLGYPSAQHIVGQRYLKGAGVVKDQEMAMHWFRRASQQNHPHGSFNLEVGKLKNITGSMEVGDIEMLLHVAARQGIQEAQELLENIIWTKSKPLPTKRVGSFL", "length": 174, "header": "tr|F6RP65-1|F6RP65_BOVIN Isoform 1 of Uncharacterized protein OS=Bos taurus OX=9913 GN=LOC511175 PE=4 SV=1 CANONICAL=F6RP65-1" }, "isoforms": [ { "isoform_ac": "F6RP65-1", "url": "https://www.uniprot.org/uniprotkb/F6RP65/entry", "sequence": { "sequence": "MTPLMPHNQKRRSQASDTHALGTILPQKYKAHARDSWSTWELLVISGSMVSLLYIWLYSQSFHFHVAHLYAHLGYPSAQHIVGQRYLKGAGVVKDQEMAMHWFRRASQQNHPHGSFNLEVGKLKNITGSMEVGDIEMLLHVAARQGIQEAQELLENIIWTKSKPLPTKRVGSFL", "length": 174, "header": "tr|F6RP65-1|F6RP65_BOVIN Isoform 1 of Uncharacterized protein OS=Bos taurus OX=9913 GN=LOC511175 PE=4 SV=1 CANONICAL=F6RP65-1" }, "locus": { "chromosome": "6", "start_pos": 24699686, "end_pos": 24679657, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000055953.3", "url": "https://www.ensembl.org/id/ENSBTAT00000055953.3" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000049166.2", "url": "https://www.ensembl.org/id/ENSBTAP00000049166.2" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [], "orthologs": [], "go_annotation": {}, "pro_annotation": [], "site_annotation": [ { "start_pos": 125, "end_pos": 127, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [ { "pdb_id": "AF-F6RP65-F1", "pdb_chain": "global", "start_pos": 1, "end_pos": 174, "overlap": "1.0", "method": "AlphaFold", "type": "alphafold", "resolution": -1.0, "url": "https://data.glygen.org/ln2downloads/pdb/current/AF-F6RP65-F1.pdb", "url_external": "https://alphafold.ebi.ac.uk/entry/F6RP65" } ], "lectin_list": [], "domain_list": [], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 125, "end_pos": 127 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ], "tool_support": { "graph_view": "yes" } }, { "uniprot_canonical_ac": "F6RQN4-1", "uniprot_ac": "F6RQN4", "uniprot_id": "F6RQN4_BOVIN", "mass": { "chemical_mass": 34953.0, "monoisotopic_mass": 34953.0 }, "refseq": { "ac": "XP_005221661", "name": "complement C1q tumor necrosis factor-related protein 3 isoform X1", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_005221661" }, "gene_names": [ { "name": "C1QTNF3", "type": "recommended", "evidence": [ { "id": "F6RQN4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F6RQN4" } ] }, { "name": "ADIM", "type": "synonym", "evidence": [ { "id": "XP_005221661", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_005221661" } ] }, { "name": "C1QTNF3", "type": "synonym", "evidence": [ { "id": "XP_005221661", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_005221661" } ] } ], "protein_names": [ { "name": "Complement C1q tumor necrosis factor-related protein 3", "type": "recommended", "evidence": [ { "id": "F6RQN4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F6RQN4/entry#names_and_taxonomy" } ] }, { "name": "Collagenous repeat-containing sequence 26 kDa protein", "type": "synonym", "evidence": [ { "id": "F6RQN4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F6RQN4/entry#names_and_taxonomy" } ] }, { "name": "Secretory protein CORS26", "type": "synonym", "evidence": [ { "id": "F6RQN4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F6RQN4/entry#names_and_taxonomy" } ] }, { "name": "complement C1q tumor necrosis factor-related protein 3 isoform X1", "type": "synonym", "evidence": [ { "id": "XP_005221661", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_005221661" } ] } ], "function": [], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Bos taurus", "taxid": 9913, "evidence": [ { "database": "UniProtKB", "id": "F6RQN4", "url": "https://www.uniprot.org/uniprotkb/F6RQN4" } ], "common_name": "Bovine", "glygen_name": "Bovine", "reference_species": "Bos taurus [9913]" } ], "gene": [ { "name": "C1QTNF3", "url": "https://www.uniprot.org/uniprotkb/F6RQN4", "locus": { "chromosome": "20", "start_pos": 39752581, "end_pos": 39720192, "strand": "-", "evidence": [ { "database": "Ensembl Gene", "id": "ENSBTAG00000017071", "url": "https://www.ensembl.org/id/ENSBTAG00000017071" } ] } } ], "crossref": [ { "id": "F6RQN4", "url": "https://alphafold.ebi.ac.uk/entry/F6RQN4", "database": "AlphaFoldDB", "categories": [] }, { "id": "531659", "url": "https://www.ncbi.nlm.nih.gov/gene/531659", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR001073", "url": "https://www.ebi.ac.uk/interpro/entry/IPR001073", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR008160", "url": "https://www.ebi.ac.uk/interpro/entry/IPR008160", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR008983", "url": "https://www.ebi.ac.uk/interpro/entry/IPR008983", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR050392", "url": "https://www.ebi.ac.uk/interpro/entry/IPR050392", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "PTHR15427", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR15427", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR15427:SF52", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR15427:SF52", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00386", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00386", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF01391", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF01391", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "XP_005221661", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_005221661", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0ABI0P0C7", "url": "https://www.uniprot.org/uniprotkb/A0ABI0P0C7", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0ABI0P0C7-1", "url": "https://www.uniprot.org/uniprotkb/A0ABI0P0C7-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "F6RQN4", "url": "https://www.uniprot.org/uniprotkb/F6RQN4", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "F6RQN4-1", "url": "https://www.uniprot.org/uniprotkb/F6RQN4-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MLGRQLVYWHLLALLFLPFCLCQDEYMEVSGRANKVVARIVQSHQQTGRSGSRREKVRERSHPRTGTVDNNTSTDLKSLRPDELPPPEVDDLAQITPFWGQSPQTGGLPPDCSKCCHGDYSFRGYQGPPGPPGPPGIPGNHGNNGNNGATGHEGAKGEKGDKGDLGPRGERGQHGPKGEKGYPGIPPELQIAFMASLATHFTNQNSGIIFSSVETNIGNFFDVMTGRFGAPVSGVYFFTFSMMKHEDVEEVYVYLMHNGNTVFSMYSYETKGKSDTSSNHAVLKLAKGDEVWLRMGNGALHGDHQRFSTFAGFLLFETK", "length": 319, "header": "tr|F6RQN4-1|F6RQN4_BOVIN Isoform 1 of Complement C1q tumor necrosis factor-related protein 3 OS=Bos taurus OX=9913 GN=C1QTNF3 PE=4 SV=1 CANONICAL=F6RQN4-1" }, "isoforms": [ { "isoform_ac": "A0ABI0P0C7-1", "url": "https://www.uniprot.org/uniprotkb/A0ABI0P0C7/entry", "sequence": { "sequence": "MRTGRQEDRRRHSLMTPFQLQYQSPQTGGLPPDCSKCCHGDYSFRGYQGPPGPPGPPGIPGNHGNNGNNGATGHEGAKGEKGDKGDLGPRGERGQHGPKGEKGYPGIPPELQIAFMASLATHFTNQNSGIIFSSVETNIGNFFDVMTGRFGAPVSGVYFFTFSMMKHEDVEEVYVYLMHNGNTVFSMYSYETKGKSDTSSNHAVLKLAKGDEVWLRMGNGALHGDHQRFSTFAGFLLFETK", "length": 241, "header": "tr|A0ABI0P0C7-1|A0ABI0P0C7_BOVIN Computationally mapped isoform of Complement C1q tumor necrosis factor-related protein 3 OS=Bos taurus OX=9913 GN=C1QTNF3 PE=4 SV=1 CANONICAL=F6RQN4-1" }, "locus": { "chromosome": "20", "start_pos": 39750691, "end_pos": 39688273, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000150890.1", "url": "https://www.ensembl.org/id/ENSBTAT00000150890.1" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000107184.1", "url": "https://www.ensembl.org/id/ENSBTAP00000107184.1" } ] } }, { "isoform_ac": "F6RQN4-1", "url": "https://www.uniprot.org/uniprotkb/F6RQN4/entry", "sequence": { "sequence": "MLGRQLVYWHLLALLFLPFCLCQDEYMEVSGRANKVVARIVQSHQQTGRSGSRREKVRERSHPRTGTVDNNTSTDLKSLRPDELPPPEVDDLAQITPFWGQSPQTGGLPPDCSKCCHGDYSFRGYQGPPGPPGPPGIPGNHGNNGNNGATGHEGAKGEKGDKGDLGPRGERGQHGPKGEKGYPGIPPELQIAFMASLATHFTNQNSGIIFSSVETNIGNFFDVMTGRFGAPVSGVYFFTFSMMKHEDVEEVYVYLMHNGNTVFSMYSYETKGKSDTSSNHAVLKLAKGDEVWLRMGNGALHGDHQRFSTFAGFLLFETK", "length": 319, "header": "tr|F6RQN4-1|F6RQN4_BOVIN Isoform 1 of Complement C1q tumor necrosis factor-related protein 3 OS=Bos taurus OX=9913 GN=C1QTNF3 PE=4 SV=1 CANONICAL=F6RQN4-1" }, "locus": { "chromosome": "20", "start_pos": 39750691, "end_pos": 39720391, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000022698.8", "url": "https://www.ensembl.org/id/ENSBTAT00000022698.8" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000022698.6", "url": "https://www.ensembl.org/id/ENSBTAP00000022698.6" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [], "orthologs": [], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 1, "go_terms": [ { "name": "extracellular region", "id": "GO:0005576", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005576", "evidence": [ { "database": "UniProtKB", "id": "F6RQN4", "url": "https://www.uniprot.org/uniprotkb/F6RQN4" } ], "pmid": "" } ] }, { "name": "Molecular Function", "total": 1, "go_terms": [ { "name": "identical protein binding", "id": "GO:0042802", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0042802", "evidence": [ { "database": "UniProtKB", "id": "F6RQN4", "url": "https://www.uniprot.org/uniprotkb/F6RQN4" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 9, "go_terms": [ { "name": "negative regulation of interleukin-6 production", "id": "GO:0032715", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0032715", "evidence": [ { "database": "UniProtKB", "id": "F6RQN4", "url": "https://www.uniprot.org/uniprotkb/F6RQN4" } ], "pmid": "" }, { "name": "negative regulation of inflammatory response", "id": "GO:0050728", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0050728", "evidence": [ { "database": "UniProtKB", "id": "F6RQN4", "url": "https://www.uniprot.org/uniprotkb/F6RQN4" } ], "pmid": "" }, { "name": "positive regulation of cytokine production", "id": "GO:0001819", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0001819", "evidence": [ { "database": "UniProtKB", "id": "F6RQN4", "url": "https://www.uniprot.org/uniprotkb/F6RQN4" } ], "pmid": "" }, { "name": "fat cell differentiation", "id": "GO:0045444", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0045444", "evidence": [ { "database": "UniProtKB", "id": "F6RQN4", "url": "https://www.uniprot.org/uniprotkb/F6RQN4" } ], "pmid": "" }, { "name": "negative regulation of non-canonical NF-kappaB signal transduction", "id": "GO:1901223", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:1901223", "evidence": [ { "database": "UniProtKB", "id": "F6RQN4", "url": "https://www.uniprot.org/uniprotkb/F6RQN4" } ], "pmid": "" }, { "name": "negative regulation of monocyte chemotactic protein-1 production", "id": "GO:0071638", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0071638", "evidence": [ { "database": "UniProtKB", "id": "F6RQN4", "url": "https://www.uniprot.org/uniprotkb/F6RQN4" } ], "pmid": "" }, { "name": "negative regulation of gluconeogenesis", "id": "GO:0045721", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0045721", "evidence": [ { "database": "UniProtKB", "id": "F6RQN4", "url": "https://www.uniprot.org/uniprotkb/F6RQN4" } ], "pmid": "" }, { "name": "intracellular triglyceride homeostasis", "id": "GO:0035356", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0035356", "evidence": [ { "database": "UniProtKB", "id": "F6RQN4", "url": "https://www.uniprot.org/uniprotkb/F6RQN4" } ], "pmid": "" }, { "name": "positive regulation of adiponectin secretion", "id": "GO:0070165", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0070165", "evidence": [ { "database": "UniProtKB", "id": "F6RQN4", "url": "https://www.uniprot.org/uniprotkb/F6RQN4" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 70, "end_pos": 72, "annotation": "n_glycosylation_sequon" }, { "start_pos": 71, "end_pos": 73, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "F6RQN4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F6RQN4" }, { "id": "PS50871", "database": "PROSITE", "url": "https://prosite.expasy.org/PS50871" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "C1q", "eco_id": "ECO_0000259", "start_pos": 186, "end_pos": 319, "start_aa": "Pro", "end_aa": "Lys", "glycosite_overlap": [] } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 70, "end_pos": 72 }, { "start_pos": 71, "end_pos": 73 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": 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"field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ], "tool_support": { "graph_view": "yes" } }, { "uniprot_canonical_ac": "F6RTG2-1", "uniprot_ac": "F6RTG2", "uniprot_id": "F6RTG2_BOVIN", "mass": { "chemical_mass": 78079.0, "monoisotopic_mass": 78079.0 }, "refseq": { "ac": "XP_005222196", "name": "pre-mRNA-processing factor 39 isoform X1", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_005222196" }, "gene_names": [ { "name": "PRPF39", "type": "recommended", "evidence": [ { "id": "F6RTG2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F6RTG2" } ] }, { "name": "PRPF39", "type": "synonym", "evidence": [ { "id": "XP_005222196", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_005222196" } ] } ], "protein_names": [ { "name": "Pre-mRNA-processing factor 39", "type": "recommended", "evidence": [ { "id": "F6RTG2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F6RTG2/entry#names_and_taxonomy" } ] }, { "name": "PRP39 homolog", "type": "synonym", "evidence": [ { "id": "F6RTG2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F6RTG2/entry#names_and_taxonomy" } ] }, { "name": "pre-mRNA-processing factor 39 isoform X1", "type": "synonym", "evidence": [ { "id": "XP_005222196", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_005222196" } ] } ], "function": [ { "annotation": "Involved in pre-mRNA splicing.", "evidence": [ { "database": "UniProtKB", "id": "F6RTG2", "url": "https://www.uniprot.org/uniprotkb/F6RTG2#function" }, { "database": "UniProtKB", "id": "ARBA00003777", "url": "https://www.uniprot.org/uniprotkb/ARBA00003777#function" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Bos taurus", "taxid": 9913, "evidence": [ { "database": "UniProtKB", "id": "F6RTG2", "url": "https://www.uniprot.org/uniprotkb/F6RTG2" } ], "common_name": "Bovine", "glygen_name": "Bovine", "reference_species": "Bos taurus [9913]" } ], "gene": [ { "name": "PRPF39", "url": "https://www.uniprot.org/uniprotkb/F6RTG2", "locus": { "chromosome": "21", "start_pos": 54844780, "end_pos": 54809719, "strand": "-", "evidence": [ { "database": "Ensembl Gene", "id": "ENSBTAG00000002603", "url": "https://www.ensembl.org/id/ENSBTAG00000002603" } ] } } ], "crossref": [ { "id": "F6RTG2", "url": "https://alphafold.ebi.ac.uk/entry/F6RTG2", "database": "AlphaFoldDB", "categories": [] }, { "id": "505547", "url": "https://www.ncbi.nlm.nih.gov/gene/505547", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR003107", "url": "https://www.ebi.ac.uk/interpro/entry/IPR003107", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR011990", "url": "https://www.ebi.ac.uk/interpro/entry/IPR011990", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR059164", "url": "https://www.ebi.ac.uk/interpro/entry/IPR059164", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IISWANL", "url": "https://omabrowser.org/oma/group/IISWANL/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "PTHR17204", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR17204", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR17204:SF5", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR17204:SF5", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF23240", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF23240", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF23241", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF23241", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "XP_005222196", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_005222196", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "F6RTG2", "url": "https://www.uniprot.org/uniprotkb/F6RTG2", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "F6RTG2-1", "url": "https://www.uniprot.org/uniprotkb/F6RTG2-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MQNSHMDEYRNSSNGSIGSSSEAAVEQSADFSTEIMNVTEMEQSPDGSPNVNTTTEENEIASTVDLPVTETEANFPPEYEKFWKTVESNPQDFTGWVYLLQYVEQENHLMAARKAFDKFFIHYPYCYGYWKKYADLEKRHDNIKQSDEVYRRGLQAIPLSVDLWIHYINFLKETLDPGDPETNSTVRGTFEHAVLAAGTDFRSDRLWEMYINWENEQGNLREVTAIYDRILGIPTQLYSHHFQRFKDHVQNNLPRDLLTGEQFIQLRRELASVNGHSGDDGPPGDDLPSGIEDITDPAKLITEIENMRHRIIEIHQEMFNYNEHEVSKRWTFEEGIKRPYFHVKPLEKAQLKNWKEYLEFEIENGTHERVVVLFERCVISCALYEEFWIKYAKYMENHSIEGVRHVFSRACTIHLPKKPMVHMLWAAFEEQQGNINEARNILRTFEECVLGLAMVRLRRVSLERRHGNMEEAERLLQEAIKNAKSNNESSFYAIKLARHLFKIQKNLPKSRKVLLEAIERDKENTKLYLNLLEMEYSGDLKQNEDNILNCFDKAIHGSLPIKMRITFSQRKVEFLEDFGSDVNKLLNAYDEHQTLLKEQDSLKRKAENGSEEPEEKKAHTEDTTSSSTQMIDGDLQANQAAYNYSAWYQYNYQTPWNYGQYYPPPPT", "length": 667, "header": "tr|F6RTG2-1|F6RTG2_BOVIN Isoform 1 of Pre-mRNA-processing factor 39 OS=Bos taurus OX=9913 GN=PRPF39 PE=3 SV=1 CANONICAL=F6RTG2-1" }, "isoforms": [ { "isoform_ac": "F6RTG2-1", "url": "https://www.uniprot.org/uniprotkb/F6RTG2/entry", "sequence": { "sequence": "MQNSHMDEYRNSSNGSIGSSSEAAVEQSADFSTEIMNVTEMEQSPDGSPNVNTTTEENEIASTVDLPVTETEANFPPEYEKFWKTVESNPQDFTGWVYLLQYVEQENHLMAARKAFDKFFIHYPYCYGYWKKYADLEKRHDNIKQSDEVYRRGLQAIPLSVDLWIHYINFLKETLDPGDPETNSTVRGTFEHAVLAAGTDFRSDRLWEMYINWENEQGNLREVTAIYDRILGIPTQLYSHHFQRFKDHVQNNLPRDLLTGEQFIQLRRELASVNGHSGDDGPPGDDLPSGIEDITDPAKLITEIENMRHRIIEIHQEMFNYNEHEVSKRWTFEEGIKRPYFHVKPLEKAQLKNWKEYLEFEIENGTHERVVVLFERCVISCALYEEFWIKYAKYMENHSIEGVRHVFSRACTIHLPKKPMVHMLWAAFEEQQGNINEARNILRTFEECVLGLAMVRLRRVSLERRHGNMEEAERLLQEAIKNAKSNNESSFYAIKLARHLFKIQKNLPKSRKVLLEAIERDKENTKLYLNLLEMEYSGDLKQNEDNILNCFDKAIHGSLPIKMRITFSQRKVEFLEDFGSDVNKLLNAYDEHQTLLKEQDSLKRKAENGSEEPEEKKAHTEDTTSSSTQMIDGDLQANQAAYNYSAWYQYNYQTPWNYGQYYPPPPT", "length": 667, "header": "tr|F6RTG2-1|F6RTG2_BOVIN Isoform 1 of Pre-mRNA-processing factor 39 OS=Bos taurus OX=9913 GN=PRPF39 PE=3 SV=1 CANONICAL=F6RTG2-1" }, "locus": { "chromosome": "21", "start_pos": 54844005, "end_pos": 54823381, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000003373.7", "url": "https://www.ensembl.org/id/ENSBTAT00000003373.7" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000003373.5", "url": "https://www.ensembl.org/id/ENSBTAP00000003373.5" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [], "orthologs": [ { "uniprot_canonical_ac": "D4A5S9-1", "protein_name": "Pre-mRNA-processing factor 39", "gene_name": "Prpf39", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MQNSHMDEYRNSDNGSTGNSSEVVIEHPDFSTEIMNVTEMEQSPDASPSVRVSTEENEMANAVDLPVTETEGNFPPEFEKFWKTVETNPQDFTGWVYLLQYVEQENHLMAARKAFDKFFIHYPYCYGYWKKYADLEKRHDNIKQSDEVYRRGLQAIPLSVDLWIHYINFLKETLDPGDPETNSTIRGTFEHAVLAAGTDFRSDKLWEMYINWENEQGNLREVTAVYDRILGIPTQLYSHHFQRFKEHVQNNLPRDLLTGEQFIQLRRELASVNGHNGDDGPPGDDLPSGIEDITDPAKLITEIENMRHRIIEIHQEMFNYNEHEVSKRWTFEEGIKRPYFHVKPLEKAQLKNWKEYLEFEIENGTHERVVVLFERCVISCALYEEFWIKYAKYMENHSIEGVRHVFSRACTVHLPKKPMAHMLWAAFEEQQGNINEARIILRTFEECVLGLAMVRLRRVSLERRHGNMEEAEHLLQDAIRNAKSNNESSFYAIKLARHLFKIQKNLPKSRKVLLEAIEKDKENTKLYLNLLEMEYSCDLKQNEENILNCFDKAIHGSLPIKMRITFSQRKVEFLEDFGSDVNKLLNAYDEHQTLLKEQDTLKRKAENGSEEPEEKKAHTEDVSSAQIIDGDLQANQAAYNYSAWYQYNYQNPWNYGQYYPPPPT", "length": 664 }, "evidence": [ { "id": "F6RTG2", "url": "https://omabrowser.org/oma/group/F6RTG2/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "Q1JPZ7-1", "protein_name": "Pre-mRNA-processing factor 39", "gene_name": "prpf39", "tax_id": 7955, "organism": "Danio rerio", "sequence": { "sequence": "MEDSGESMTGMLDSKSPESGDSPAMEGTTGTDDVTGLSTSDLTTEQPPESQEQTQPVSDMEFSVEHLKTAVQNIDQSASPAEPAAENSEQPPESNGQQEDQSEQPDDVKEAGQGDSESPSNMELEDAPKEPAEPAAEADPAAPQEPELPTEYERLSKVVEDNPEDFNGWVYLLQYVEQENHLLGSRKAFDAFFLHYPYCYGYWKKYADIERKHGYIQMADEVYRRGLQAIPLSVDLWLHYITFLRENQDTSDGEAESRIRASYEHAVLACGTDFRSDRLWEAYIAWETEQGKLANVTAIYDRLLCIPTQLYSQHFQKFKDHVQSNNPKHFLSEEEFVSLRVELANANKPSGDEDAETEAPGEELPPGTEDLPDPAKRVTEIENMRHKVIETRQEMFNHNEHEVSKRWAFEEGIKRPYFHVKALEKTQLNNWREYLDFELENGTPERVVVLFERCLIACALYEEFWIKYAKYLESYSTEAVRHIYKKACTVHLPKKPNVHLLWAAFEEQQGSIDEARSILKAVEVSVPGLAMVRLRRVSLERRHGNMEEAEALLQDAITNGRNSSESSFYSVKLARQLVKVQKSIGRAKKVLLEAVEKDETNPKLYLNLLELEYSGDVQQNEAEIIACFDRALSSSMALESRITFSQRKVDFLEDFGSDINTLMAAYEQHQRLLAEQESFKRKAENGSEEPDAKRQRTDDQSVASGQMMDMQANHAGYNYNNWYQYNSWGSQNSWGQYGQYGQYNQYYPPPPT", "length": 752 }, "evidence": [ { "id": "F6RTG2", "url": "https://omabrowser.org/oma/group/F6RTG2/", "database": "OMA" } ], "glygen_name": "Zebrafish", "common_name": "Zebrafish" }, { "uniprot_canonical_ac": "Q54R91-1", "protein_name": "Tetratricopeptide-like helical domain-containing protein", "gene_name": "prpf39", "tax_id": 44689, "organism": "Dictyostelium discoideum", "sequence": { "sequence": "MTEVTTTPPTTSTPTTSPQNLSEEDKLWKIVQTNPLAFNQWTFLIGVIEKTNDIEKIRKVYSEFLNEFPLCFLYWKRFADHEYAHNNTTQSIEIFEKAVSSIPHSVDIWLNYCTHLIDKSYPVDEIRSVFKRGINIIGTDYQSGKFWEKYIEFEMGQENNELASIFNSILKTPLENLQIFNEKFKDNIDRIKINDMLTEEERKEYTGYDAETKQMVLQNREKWYHETLEKISKRSNFESIVNKRFFFHIQPIDEMTLSVWRSYFNYMESDPSVTQEEVIKLFERCLVPCCYYSEFWLKYIKFLQESYVGDNKNELIESIFERATKIFLKKRADIHLEYSLFVESTLGNIEKAFSILENIHSLLPTHLEVILRLVSFKRRNHSIQQANQFFKKVLTSLQSDSKTYPFLSINYISFLLSNKQSLQGEKEGEEEADKIVDVFETSREVLKKSISLYPDSKLLWLYFINFEINNLLFIISGSGSSEKRIEQIERIKKVYNIALCLDKNKIKNNGKENKEENKEENKENTNNEEKEKEKDDEEKDDEEKDGNEILVCKLNDDEKLNIWNDYLEFNLQYDNDIKGYKELKNKFESLYPDGKPESKKRSLTDMNLQSSSSSSSSTTNGIINNGNNDGPLNKRVAYSVPPTSNNNGVIQNNSYIYQQQQAQPQHHHQQQQHHHQQHIQQQQQHHQQQHQGFYGGYGY", "length": 699 }, "evidence": [ { "id": "F6RTG2", "url": "https://omabrowser.org/oma/group/F6RTG2/", "database": "OMA" } ], "glygen_name": "Cellular slime mold", "common_name": "Social amoeba" }, { "uniprot_canonical_ac": "Q86UA1-1", "protein_name": "Pre-mRNA-processing factor 39", "gene_name": "PRPF39", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MQNSHMDEYRNSSNGSTGNSSEVVVEHPTDFSTEIMNVTEMEQSPDDSPNVNASTEETEMASAVDLPVTLTETEANFPPEYEKFWKTVENNPQDFTGWVYLLQYVEQENHLMAARKAFDRFFIHYPYCYGYWKKYADLEKRHDNIKPSDEVYRRGLQAIPLSVDLWIHYINFLKETLDPGDPETNNTIRGTFEHAVLAAGTDFRSDRLWEMYINWENEQGNLREVTAIYDRILGIPTQLYSHHFQRFKEHVQNNLPRDLLTGEQFIQLRRELASVNGHSGDDGPPGDDLPSGIEDITDPAKLITEIENMRHRIIEIHQEMFNYNEHEVSKRWTFEEGIKRPYFHVKPLEKAQLKNWKEYLEFEIENGTHERVVVLFERCVISCALYEEFWIKYAKYMENHSIEGVRHVFSRACTIHLPKKPMVHMLWAAFEEQQGNINEARNILKTFEECVLGLAMVRLRRVSLERRHGNLEEAEHLLQDAIKNAKSNNESSFYAVKLARHLFKIQKNLPKSRKVLLEAIERDKENTKLYLNLLEMEYSGDLKQNEENILNCFDKAVHGSLPIKMRITFSQRKVEFLEDFGSDVNKLLNAYDEHQTLLKEQDSLKRKAENGSEEPEEKKAHTEDTTSSSTQMIDGDLQANQAVYNYSAWYQYNYQNPWNYGQYYPPPPT", "length": 669 }, "evidence": [ { "id": "F6RTG2", "url": "https://omabrowser.org/oma/group/F6RTG2/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "Q8K2Z2-1", "protein_name": "Pre-mRNA-processing factor 39", "gene_name": "Prpf39", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MQNSHMEEYRNSDNGSTGNSSEVAVVEHPDFSTEIMNVTEMEQSPDASPSAHASTEENEMANAVNLPVTEAEGDFPPEFEKFWKTVEMNPQDFTGWVYLLQYVEQENHLMAARKAFDKFFVHYPYCYGYWKKYADLEKRHDNIKQSDEVYRRGLQAIPLSVDLWIHYINFLKETLEPGDQETNTTIRGTFEHAVLAAGTDFRSDKLWEMYINWENEQGNLREVTAVYDRILGIPTQLYSHHFQRFKEHVQNNLPRDLLTGEQFIQLRRELASVNGHSGDDGPPGDDLPSGIEDISPAKLITEIENMRHRIIEIHQEMFNYNEHEVSKRWTFEEGIKRPYFHVKPLEKAQPKKNWKEYLEFEIENGTHERVVVLFERCVISCALYEEFWIKYAKYMENHSIEGVRHVFSRACTVHLPKKPMAHMLWAAFEEQQGNINEARIILRTFEECVLGLAMVRLRRVSLERRHGNMEEAEHLLQDAIKNAKSNNESSFYAIKLARHLFKIQKNLPKSRKVLLEAIEKDKENTKLYLNLLEMEYSCDLKQNEENILNCFDKAIHGSLPIKMRITFSQRKVEFLEDFGSDVNKLLNAYDEHQTLLKEQDTLKRKAENGSEEPEEKKAHTEDLSSAQIIDGDLQANQAAYNYSAWYQYNYQNPWNYGQYYPPPPT", "length": 665 }, "evidence": [ { "id": "F6RTG2", "url": "https://omabrowser.org/oma/group/F6RTG2/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q93ZR3-1", "protein_name": "Pre-mRNA-processing factor 39-1", "gene_name": "PRP39-1", "tax_id": 3702, "organism": "Arabidopsis thaliana", "sequence": { "sequence": "MGDSEAMVSEGYTSAPYGDYNASAATVESTGQETAPIVDASHSVNNDSLVNGTAPVENGSATDNVAVTAPAAEHGDNTGSTLSTEEERLWNIVRANSLEFNAWTALIDETERIAQDNIAKIRKVYDAFLAEFPLCYGYWKKFADHEARVGAMDKVVEVYERAVLGVTYSVDIWLHYCTFAINTYGDPETIRRLFERALVYVGTDFLSSPLWDKYIEYEYMQQDWSRVALIYTRILENPIQNLDRYFSSFKELAETRPLSELRSAEESAAAAVAVAGDASESAASESGEKADEGRSQVDGSTEQSPKLESASSTEPEELKKYVGIREAMYIKSKEFESKIIGYEMAIRRPYFHVRPLNVAELENWHNYLDFIERDGDFNKVVKLYERCVVTCANYPEYWIRYVTNMEASGSADLAENALARATQVFVKKQPEIHLFAARLKEQNGDIAGARAAYQLVHSEISPGLLEAVIKHANMEYRLGNLDDAFSLYEQVIAVEKGKEHSTILPLLYAQYSRFSYLVSRDAEKARRIIVEALDHVQPSKPLMEALIHFEAIQPPPREIDYLEPLVEKVIKPDADAQNIASSTEREELSLIYIEFLGIFGDVKSIKKAEDQHVKLFYPHRSTSELKKRSADDFLASDRTKMAKTYNGTPPAQPVSNAYPNAQAQWSGGYAAQPQTWPPAQAAPAQPQQWNPAYGQQAAYGAYGGYPAGYTAPQAPTPVPQAAAYGAYPAQTYPTQSYAPPVAAAAPAAAPVQQPAAAVAPQAYYNTYY", "length": 768 }, "evidence": [ { "id": "F6RTG2", "url": "https://omabrowser.org/oma/group/F6RTG2/", "database": "OMA" } ], "glygen_name": "Arabidopsis", "common_name": "Mouse-ear cress" } ], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 1, "go_terms": [ { "name": "nucleus", "id": "GO:0005634", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005634", "evidence": [ { "database": "UniProtKB", "id": "F6RTG2", "url": "https://www.uniprot.org/uniprotkb/F6RTG2" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 2, "go_terms": [ { "name": "mRNA processing", "id": "GO:0006397", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006397", "evidence": [ { "database": "UniProtKB", "id": "F6RTG2", "url": "https://www.uniprot.org/uniprotkb/F6RTG2" } ], "pmid": "" }, { "name": "RNA splicing", "id": "GO:0008380", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008380", "evidence": [ { "database": "UniProtKB", "id": "F6RTG2", "url": "https://www.uniprot.org/uniprotkb/F6RTG2" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 11, "end_pos": 13, "annotation": "n_glycosylation_sequon" }, { "start_pos": 14, "end_pos": 16, "annotation": "n_glycosylation_sequon" }, { "start_pos": 183, "end_pos": 185, "annotation": "n_glycosylation_sequon" }, { "start_pos": 364, "end_pos": 366, "annotation": "n_glycosylation_sequon" }, { "start_pos": 37, "end_pos": 39, "annotation": "n_glycosylation_sequon" }, { "start_pos": 397, "end_pos": 399, "annotation": "n_glycosylation_sequon" }, { "start_pos": 487, "end_pos": 489, "annotation": "n_glycosylation_sequon" }, { "start_pos": 52, "end_pos": 54, "annotation": "n_glycosylation_sequon" }, { "start_pos": 608, "end_pos": 610, "annotation": "n_glycosylation_sequon" }, { "start_pos": 643, "end_pos": 645, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "homologset.oma", "label": "OMA Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 11, "end_pos": 13 }, { "start_pos": 14, "end_pos": 16 }, { "start_pos": 183, "end_pos": 185 }, { "start_pos": 364, "end_pos": 366 }, { "start_pos": 37, "end_pos": 39 }, { "start_pos": 397, "end_pos": 399 }, { "start_pos": 487, "end_pos": 489 }, { "start_pos": 52, "end_pos": 54 }, { "start_pos": 608, "end_pos": 610 }, { "start_pos": 643, "end_pos": 645 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ], "tool_support": { "graph_view": "yes" } }, { "uniprot_canonical_ac": "F6RTK8-1", "uniprot_ac": "F6RTK8", "uniprot_id": "F6RTK8_BOVIN", "mass": { "chemical_mass": 31133.0, "monoisotopic_mass": 31133.0 }, "refseq": {}, "gene_names": [ { "name": "PDCD1", "type": "recommended", "evidence": [ { "id": "F6RTK8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F6RTK8" } ] } ], "protein_names": [ { "name": "Programmed cell death 1", "type": "synonym", "evidence": [ { "id": "F6RTK8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F6RTK8/entry#names_and_taxonomy" } ] } ], "function": [], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Bos taurus", "taxid": 9913, "evidence": [ { "database": "UniProtKB", "id": "F6RTK8", "url": "https://www.uniprot.org/uniprotkb/F6RTK8" } ], "common_name": "Bovine", "glygen_name": "Bovine", "reference_species": "Bos taurus [9913]" } ], "gene": [ { "name": "PDCD1", "url": "https://www.uniprot.org/uniprotkb/F6RTK8", "locus": { "chromosome": "3", "start_pos": 120838419, "end_pos": 120848837, "strand": "+", "evidence": [ { "database": "Ensembl Gene", "id": "ENSBTAG00000011543", "url": "https://www.ensembl.org/id/ENSBTAG00000011543" } ] } } ], "crossref": [ { "id": "F6RTK8", "url": "https://alphafold.ebi.ac.uk/entry/F6RTK8", "database": "AlphaFoldDB", "categories": [] }, { "id": "cd16088", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd16088", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "IPR003599", "url": "https://www.ebi.ac.uk/interpro/entry/IPR003599", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR007110", "url": "https://www.ebi.ac.uk/interpro/entry/IPR007110", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR013106", "url": "https://www.ebi.ac.uk/interpro/entry/IPR013106", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR013783", "url": "https://www.ebi.ac.uk/interpro/entry/IPR013783", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR036179", "url": "https://www.ebi.ac.uk/interpro/entry/IPR036179", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR042379", "url": "https://www.ebi.ac.uk/interpro/entry/IPR042379", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "PTHR15264", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR15264", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR15264:SF2", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR15264:SF2", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF07686", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF07686", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "F6RTK8", "url": "https://www.uniprot.org/uniprotkb/F6RTK8", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "F6RTK8-1", "url": "https://www.uniprot.org/uniprotkb/F6RTK8-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MGTPRALWPLVWAVLQLGCWPGWLLEASSRPWSALTFSPPRLVVPEGANATFTCSFSSKPERFVLNWYRKSPSNQMDKLAAFPEDRSQPSRDRRFRVTPLPDGQQFNMSIVAAQRNDSGVYFCGAIYLPPRTQINESHSAELMVTEAVLEPPTEPPSPQPRPEGQMQSLVIGVTSVLLGVLLLPPLIWVLAAVFLRATRGGCARRSQDQPPEGCPSVPAVTVDYGELDFQWREKTPEPAAPCVPEQTEYATIVFPGRRASADSPQGPWPLRTEDGHCSWPL", "length": 281, "header": "tr|F6RTK8-1|F6RTK8_BOVIN Isoform 1 of Programmed cell death 1 OS=Bos taurus OX=9913 GN=PDCD1 PE=4 SV=2 CANONICAL=F6RTK8-1" }, "isoforms": [ { "isoform_ac": "F6RTK8-1", "url": "https://www.uniprot.org/uniprotkb/F6RTK8/entry", "sequence": { "sequence": "MGTPRALWPLVWAVLQLGCWPGWLLEASSRPWSALTFSPPRLVVPEGANATFTCSFSSKPERFVLNWYRKSPSNQMDKLAAFPEDRSQPSRDRRFRVTPLPDGQQFNMSIVAAQRNDSGVYFCGAIYLPPRTQINESHSAELMVTEAVLEPPTEPPSPQPRPEGQMQSLVIGVTSVLLGVLLLPPLIWVLAAVFLRATRGGCARRSQDQPPEGCPSVPAVTVDYGELDFQWREKTPEPAAPCVPEQTEYATIVFPGRRASADSPQGPWPLRTEDGHCSWPL", "length": 281, "header": "tr|F6RTK8-1|F6RTK8_BOVIN Isoform 1 of Programmed cell death 1 OS=Bos taurus OX=9913 GN=PDCD1 PE=4 SV=2 CANONICAL=F6RTK8-1" }, 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"MMAAGASGPHGIRVRVFRSLAREDRKRRRFVSIDWLKLEAFLLLIGSVLRGKEFVAPAKSRYCAAGAAGVLKRFGEPSSENLLELSPEGIVSKMWNSGFESYSTSSFGGAGGYTQSPGGFGSPTASQAEKKSRARAQHIVPCTISQLLSATLVDEVFRIGNVEISQVTIVGIIRNAEKAATNIVYKIDDMTAAPMDVRQWVDTDDASSENTVVPPETYVKVAGHLRSFQNKKSLVAFKIIPLEDMNEFTTHILEVVNAHMMLSKSNSQPSAGRAPISNPGMGEAGNFGGNNFIPANGLTVAQNQVLNLIKACPRPEGLNFQDLKNQLQHMSVASIKLAVDFLSNEGHIYSTVDDDHFKSTDAE", "length": 363, "header": "tr|F6RU89-1|F6RU89_BOVIN Isoform 1 of Replication protein A 32 kDa subunit OS=Bos taurus OX=9913 GN=RPA2 PE=3 SV=1 CANONICAL=F6RU89-1" }, "locus": { "chromosome": "2", "start_pos": 125470034, "end_pos": 125448134, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000008174.7", "url": "https://www.ensembl.org/id/ENSBTAT00000008174.7" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000008174.5", "url": "https://www.ensembl.org/id/ENSBTAP00000008174.5" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [], "orthologs": [], "go_annotation": { "categories": [ { "name": "Molecular Function", "total": 1, "go_terms": [ { "name": "DNA binding", "id": "GO:0003677", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003677", "evidence": [ { "database": "UniProtKB", "id": "F6RU89", "url": "https://www.uniprot.org/uniprotkb/F6RU89" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 3, "go_terms": [ { "name": "DNA repair", "id": "GO:0006281", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006281", "evidence": [ { "database": "UniProtKB", "id": "F6RU89", "url": "https://www.uniprot.org/uniprotkb/F6RU89" } ], "pmid": "" }, { "name": "DNA recombination", "id": "GO:0006310", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006310", "evidence": [ { "database": "UniProtKB", "id": "F6RU89", "url": "https://www.uniprot.org/uniprotkb/F6RU89" } ], "pmid": "" }, { "name": "DNA replication", "id": "GO:0006260", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006260", "evidence": [ { "database": "UniProtKB", "id": "F6RU89", "url": "https://www.uniprot.org/uniprotkb/F6RU89" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 1, "go_terms": [ { "name": "PML body", "id": "GO:0016605", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016605", "evidence": [ { "database": "UniProtKB", "id": "F6RU89", "url": "https://www.uniprot.org/uniprotkb/F6RU89" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "F6RU89", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F6RU89" }, { "id": "PF01336", "database": "Pfam", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF01336" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "OB", "eco_id": "ECO_0000259", "start_pos": 167, "end_pos": 242, "start_aa": "Val", "end_aa": "Leu", "glycosite_overlap": [] }, { "evidence": [ { "id": "F6RU89", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F6RU89" }, { "id": "PF08784", "database": "Pfam", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF08784" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "Replication protein A C-terminal", "eco_id": "ECO_0000259", "start_pos": 259, "end_pos": 355, "start_aa": "His", "end_aa": "Asp", "glycosite_overlap": [] } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": 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"o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ], "tool_support": { "graph_view": "yes" } }, { "uniprot_canonical_ac": "F6RV75-1", "uniprot_ac": "F6RV75", "uniprot_id": "F6RV75_BOVIN", "mass": { "chemical_mass": 73791.0, "monoisotopic_mass": 73791.0 }, "refseq": {}, "gene_names": [ { "name": "TRIOBP", "type": "recommended", "evidence": [ { "id": "F6RV75", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F6RV75" } ] } ], "protein_names": [ { "name": "TRIO and F-actin binding protein", "type": "synonym", "evidence": [ { "id": "F6RV75", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F6RV75/entry#names_and_taxonomy" } ] } ], "function": [], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Bos taurus", "taxid": 9913, "evidence": [ { "database": "UniProtKB", "id": "F6RV75", "url": "https://www.uniprot.org/uniprotkb/F6RV75" } ], "common_name": "Bovine", "glygen_name": "Bovine", "reference_species": "Bos taurus [9913]" } ], "gene": [ { "name": "TRIOBP", "url": "https://www.uniprot.org/uniprotkb/F6RV75", "locus": { "chromosome": "5", "start_pos": 109589526, "end_pos": 109562534, "strand": "-", "evidence": [ { "database": "Ensembl Gene", "id": "ENSBTAG00000002539", "url": "https://www.ensembl.org/id/ENSBTAG00000002539" } ] } } ], "crossref": [ { "id": "F6RV75", "url": "https://alphafold.ebi.ac.uk/entry/F6RV75", "database": "AlphaFoldDB", "categories": [] }, { "id": "cd13275", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd13275", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "IPR001849", "url": "https://www.ebi.ac.uk/interpro/entry/IPR001849", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR011993", "url": "https://www.ebi.ac.uk/interpro/entry/IPR011993", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR039597", "url": "https://www.ebi.ac.uk/interpro/entry/IPR039597", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR052223", "url": "https://www.ebi.ac.uk/interpro/entry/IPR052223", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "PTHR17271", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR17271", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR17271:SF10", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR17271:SF10", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00169", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00169", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "F6RV75", "url": "https://www.uniprot.org/uniprotkb/F6RV75", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "F6RV75-1", "url": "https://www.uniprot.org/uniprotkb/F6RV75-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "TGGWKGLGQRRGREGPEERRLAAERGGGGGGIPAPLSPARESFPPSCLLLLPPLGADMTPDLLNFKKGWMSILDEPGEPRPLLTAISPSQWKKHWFVLTDSSLKYYRDSTAEEADELDGEIDLRSCTDVTEYAVQRNYGFQIHTKDAVYTLSAMTSGIRRNWIEALRKTVRPTSAPDVTKLSDCNKENTLHSYGTPKGSLKAGEQRVGSEVISRGGPRKADGQRQLLDYVELSPLTQGSPQRARTPARTLDRPAKQEELERDLAQRSEERRKWFEATDSRATETPAGEGPRRVLGAPLTEDQQSRLSEEIEKKWQELEKLPLRENKRVPLTALLNQGRGERRGAPSDSHEALEKEVQSLRAQLEAWRLQGEAPQGAPKSQEDGHIPPGYISQEACERSLAEMESSHQQVMQELQRHHERELQRLQQEKEWLLAEETAATASAIEAMKKAYQEELSRELNKTRTLQQGPDGLRKQHQSDVEALKRELQVLSEQYSQKCLEIGALTRQAEEREHTLRRCQQEGQELLRHNQELHTRLSEEIDRLRSFIASQGTGNGCGRSSERSSCELEVLLRVKENELQYLKKEVQCLRDELQMMQKDKRFTSGKYQDVYVELNHIKTRSEREIEQLKEHLRLAMAALQEKEAVRNSLAE", "length": 649, "header": "tr|F6RV75-1|F6RV75_BOVIN Isoform 1 of TRIO and F-actin binding protein OS=Bos taurus OX=9913 GN=TRIOBP PE=4 SV=2 CANONICAL=F6RV75-1" }, "isoforms": [ { "isoform_ac": "F6RV75-1", "url": "https://www.uniprot.org/uniprotkb/F6RV75/entry", "sequence": { "sequence": "TGGWKGLGQRRGREGPEERRLAAERGGGGGGIPAPLSPARESFPPSCLLLLPPLGADMTPDLLNFKKGWMSILDEPGEPRPLLTAISPSQWKKHWFVLTDSSLKYYRDSTAEEADELDGEIDLRSCTDVTEYAVQRNYGFQIHTKDAVYTLSAMTSGIRRNWIEALRKTVRPTSAPDVTKLSDCNKENTLHSYGTPKGSLKAGEQRVGSEVISRGGPRKADGQRQLLDYVELSPLTQGSPQRARTPARTLDRPAKQEELERDLAQRSEERRKWFEATDSRATETPAGEGPRRVLGAPLTEDQQSRLSEEIEKKWQELEKLPLRENKRVPLTALLNQGRGERRGAPSDSHEALEKEVQSLRAQLEAWRLQGEAPQGAPKSQEDGHIPPGYISQEACERSLAEMESSHQQVMQELQRHHERELQRLQQEKEWLLAEETAATASAIEAMKKAYQEELSRELNKTRTLQQGPDGLRKQHQSDVEALKRELQVLSEQYSQKCLEIGALTRQAEEREHTLRRCQQEGQELLRHNQELHTRLSEEIDRLRSFIASQGTGNGCGRSSERSSCELEVLLRVKENELQYLKKEVQCLRDELQMMQKDKRFTSGKYQDVYVELNHIKTRSEREIEQLKEHLRLAMAALQEKEAVRNSLAE", "length": 649, "header": "tr|F6RV75-1|F6RV75_BOVIN Isoform 1 of TRIO and F-actin binding protein OS=Bos taurus OX=9913 GN=TRIOBP PE=4 SV=2 CANONICAL=F6RV75-1" }, "locus": { "chromosome": "5", "start_pos": 109589521, "end_pos": 109567276, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000003297.7", "url": "https://www.ensembl.org/id/ENSBTAT00000003297.7" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000003297.6", "url": "https://www.ensembl.org/id/ENSBTAP00000003297.6" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [], "orthologs": [], "go_annotation": {}, "pro_annotation": [], "site_annotation": [ { "start_pos": 459, "end_pos": 461, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "F6RV75", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F6RV75" }, { "id": "PS50003", "database": "PROSITE", "url": "https://prosite.expasy.org/PS50003" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "PH", "eco_id": "ECO_0000259", "start_pos": 63, "end_pos": 171, "start_aa": "Leu", "end_aa": "Arg", "glycosite_overlap": [] } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 459, "end_pos": 461 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ], "tool_support": { "graph_view": "yes" } }, { "uniprot_canonical_ac": "F6RVL5-1", "uniprot_ac": "F6RVL5", "uniprot_id": "F6RVL5_BOVIN", "mass": { "chemical_mass": 88181.0, "monoisotopic_mass": 88181.0 }, "refseq": {}, "gene_names": [ { "name": "RGL2", "type": "recommended", "evidence": [ { "id": "F6RVL5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F6RVL5" } ] } ], "protein_names": [ { "name": "Ral guanine nucleotide dissociation stimulator-like 2", "type": "recommended", "evidence": [ { "id": "F6RVL5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F6RVL5/entry#names_and_taxonomy" } ] }, { "name": "Ras-associated protein RAB2L", "type": "synonym", "evidence": [ { "id": "F6RVL5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F6RVL5/entry#names_and_taxonomy" } ] } ], "function": [ { "annotation": "Probable guanine nucleotide exchange factor. Putative effector of Ras and/or Rap. 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"F6RVL5", "url": "https://alphafold.ebi.ac.uk/entry/F6RVL5", "database": "AlphaFoldDB", "categories": [] }, { "id": "cd00155", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd00155", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "cd06224", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd06224", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "cd17211", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd17211", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "IPR000159", "url": "https://www.ebi.ac.uk/interpro/entry/IPR000159", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR000651", "url": "https://www.ebi.ac.uk/interpro/entry/IPR000651", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR001895", "url": "https://www.ebi.ac.uk/interpro/entry/IPR001895", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR008937", "url": "https://www.ebi.ac.uk/interpro/entry/IPR008937", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR019804", "url": "https://www.ebi.ac.uk/interpro/entry/IPR019804", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR023578", "url": "https://www.ebi.ac.uk/interpro/entry/IPR023578", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR029071", "url": "https://www.ebi.ac.uk/interpro/entry/IPR029071", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR036964", "url": "https://www.ebi.ac.uk/interpro/entry/IPR036964", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "PTHR23113", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR23113", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR23113:SF350", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR23113:SF350", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00617", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00617", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF00618", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00618", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF00788", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00788", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "F6RVL5", "url": "https://www.uniprot.org/uniprotkb/F6RVL5", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "F6RVL5-1", "url": "https://www.uniprot.org/uniprotkb/F6RVL5-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": 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"tr|F6RVL5-1|F6RVL5_BOVIN Isoform 1 of Ral guanine nucleotide dissociation stimulator-like 2 OS=Bos taurus OX=9913 GN=RGL2 PE=4 SV=1 CANONICAL=F6RVL5-1" }, "locus": { "chromosome": "23", "start_pos": 7472376, "end_pos": 7466045, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000022385.5", "url": "https://www.ensembl.org/id/ENSBTAT00000022385.5" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000022385.4", "url": "https://www.ensembl.org/id/ENSBTAP00000022385.4" } ] } } ], "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "other", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 589, "start_aa": "Thr", "end_pos": 589, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr589", "evidence": [ { "id": "", "database": "GlyGen", "url": "https://data.glygen.org/" } ], "filter_code": "000000000000000010000.00000000001000.0.01000" } ], "phosphorylation": [], "glycation": [], "keywords": [ "glycoprotein", "glycoprotein_predicted" ], "publication": [], "pathway": [], "orthologs": [], "go_annotation": { "categories": [ { "name": "Molecular Function", "total": 1, "go_terms": [ { "name": "guanyl-nucleotide exchange factor activity", "id": "GO:0005085", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005085", "evidence": [ { "database": "UniProtKB", "id": "F6RVL5", "url": "https://www.uniprot.org/uniprotkb/F6RVL5" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 1, "go_terms": [ { "name": "small GTPase-mediated signal transduction", "id": "GO:0007264", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007264", "evidence": [ { "database": "UniProtKB", "id": "F6RVL5", "url": "https://www.uniprot.org/uniprotkb/F6RVL5" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 392, "end_pos": 394, "annotation": "n_glycosylation_sequon" }, { "start_pos": 438, "end_pos": 440, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "F6RVL5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F6RVL5" }, { "id": "PS50212", "database": "PROSITE", "url": "https://prosite.expasy.org/PS50212" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "N-terminal Ras-GEF", "eco_id": "ECO_0000259", "start_pos": 133, "end_pos": 257, "start_aa": "Ser", "end_aa": "Arg", "glycosite_overlap": [] }, { "evidence": [ { "id": "F6RVL5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F6RVL5" }, { "id": "PS50009", "database": "PROSITE", "url": "https://prosite.expasy.org/PS50009" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": 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"field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 1 }, { "field": "total_sites", "count": 1 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 1 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": 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"field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ], "tool_support": { "graph_view": "yes" } }, { "uniprot_canonical_ac": "F6RXG8-1", "uniprot_ac": "F6RXG8", "uniprot_id": "F6RXG8_BOVIN", "mass": { "chemical_mass": 33768.0, "monoisotopic_mass": 33768.0 }, "refseq": {}, "gene_names": [ { "name": "RGCC", "type": "recommended", "evidence": [ { "id": "F6RXG8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F6RXG8" } ] } ], "protein_names": [ { "name": "Regulator of cell cycle", "type": "synonym", "evidence": [ { "id": "F6RXG8", "database": "UniProtKB", "url": 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"categories": [ "Gene Expression" ] }, { "id": "IPR029252", "url": "https://www.ebi.ac.uk/interpro/entry/IPR029252", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "PTHR32193", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR32193", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR32193:SF3", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR32193:SF3", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF15151", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF15151", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "F6RXG8", "url": "https://www.uniprot.org/uniprotkb/F6RXG8", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "F6RXG8-1", "url": "https://www.uniprot.org/uniprotkb/F6RXG8-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": 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cell cycle OS=Bos taurus OX=9913 GN=RGCC PE=4 SV=1 CANONICAL=F6RXG8-1" }, "locus": { "chromosome": "12", "start_pos": 11609798, "end_pos": 11594527, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000049347.5", "url": "https://www.ensembl.org/id/ENSBTAT00000049347.5" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000046249.3", "url": "https://www.ensembl.org/id/ENSBTAP00000046249.3" } ] } } ], "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "other", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 283, "start_aa": "Thr", "end_pos": 283, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr283", "evidence": [ { "id": "", "database": "GlyGen", "url": "https://data.glygen.org/" } ], "filter_code": 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"phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ], "tool_support": { "graph_view": "yes" } }, { "uniprot_canonical_ac": "F6S0K2-1", "uniprot_ac": "F6S0K2", "uniprot_id": "F6S0K2_BOVIN", "mass": { "chemical_mass": 43769.0, "monoisotopic_mass": 43769.0 }, "refseq": { "ac": "XP_059732772", "name": "inactive serine protease 54 isoform X3", "summary": "", "url": 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{ "id": "529251", "url": "https://www.ncbi.nlm.nih.gov/gene/529251", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR001254", "url": "https://www.ebi.ac.uk/interpro/entry/IPR001254", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR009003", "url": "https://www.ebi.ac.uk/interpro/entry/IPR009003", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR043504", "url": "https://www.ebi.ac.uk/interpro/entry/IPR043504", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "PTHR24250", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR24250", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR24250:SF45", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR24250:SF45", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00089", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00089", 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] }, { "id": "PTHR11851:SF116", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR11851:SF116", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00675", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00675", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF05193", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF05193", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "R-BTA-611105", "url": "https://www.reactome.org/PathwayBrowser/#R-BTA-611105", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "R-BTA-9865881", "url": "https://www.reactome.org/PathwayBrowser/#R-BTA-9865881", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "NP_777054", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_777054", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "G1K1X0", "url": "https://www.uniprot.org/uniprotkb/G1K1X0", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "G1K1X0-1", "url": "https://www.uniprot.org/uniprotkb/G1K1X0-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MAASAVCRAAGAGTRVLLRTRRSPALLRSSDLRGTATYAQALQSVPETQVSQLDNGLRVASEQSSQPTCTVGVWIDAGSRYETEKNNGAGYFVEHLAFKGTKNRPGNALEKEVESMGAHLNAYSTREHTAYYIKALSKDLPKAVELLADIVQNCSLEDSQIEKERDVILQELQENDTSMRDVVFNYLHATAFQGTPLAQSVEGPSENVRKLSRADLTEYLSRHYKAPRMVLAAAGGLEHRQLLDLAQKHFSGLSGTYDEDAVPTLSPCRFTGSQICHREDGLPLAHVAIAVEGPGWAHPDNVALQVANAIIGHYDCTYGGGAHLSSPLASIAATNKLCQSFQTFNICYADTGLLGAHFVCDHMSIDDMMFVLQGQWMRLCTSATESEVLRGKNLLRNALVSHLDGTTPVCEDIGRSLLTYGRRIPLAEWESRIAEVDARVVREVCSKYFYDQCPAVAGFGPIEQLPDYNRIRSGMFWLRF", "length": 480, "header": "tr|G1K1X0-1|G1K1X0_BOVIN Isoform 1 of Cytochrome b-c1 complex subunit 1, mitochondrial OS=Bos taurus OX=9913 GN=UQCRC1 PE=3 SV=1 CANONICAL=G1K1X0-1" }, "isoforms": [ { "isoform_ac": "G1K1X0-1", "url": "https://www.uniprot.org/uniprotkb/G1K1X0/entry", "sequence": { "sequence": "MAASAVCRAAGAGTRVLLRTRRSPALLRSSDLRGTATYAQALQSVPETQVSQLDNGLRVASEQSSQPTCTVGVWIDAGSRYETEKNNGAGYFVEHLAFKGTKNRPGNALEKEVESMGAHLNAYSTREHTAYYIKALSKDLPKAVELLADIVQNCSLEDSQIEKERDVILQELQENDTSMRDVVFNYLHATAFQGTPLAQSVEGPSENVRKLSRADLTEYLSRHYKAPRMVLAAAGGLEHRQLLDLAQKHFSGLSGTYDEDAVPTLSPCRFTGSQICHREDGLPLAHVAIAVEGPGWAHPDNVALQVANAIIGHYDCTYGGGAHLSSPLASIAATNKLCQSFQTFNICYADTGLLGAHFVCDHMSIDDMMFVLQGQWMRLCTSATESEVLRGKNLLRNALVSHLDGTTPVCEDIGRSLLTYGRRIPLAEWESRIAEVDARVVREVCSKYFYDQCPAVAGFGPIEQLPDYNRIRSGMFWLRF", "length": 480, "header": "tr|G1K1X0-1|G1K1X0_BOVIN Isoform 1 of Cytochrome b-c1 complex subunit 1, mitochondrial OS=Bos taurus OX=9913 GN=UQCRC1 PE=3 SV=1 CANONICAL=G1K1X0-1" }, "locus": { "chromosome": "22", "start_pos": 51283699, "end_pos": 51275075, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000025422.5", "url": "https://www.ensembl.org/id/ENSBTAT00000025422.5" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000025422.3", "url": "https://www.ensembl.org/id/ENSBTAP00000025422.3" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [ { "title": "Functional UQCRC1 polymorphisms affect promoter activity and body lipid accumulation.", "journal": "Obesity (Silver Spring, Md.)", "date": "2007-12", "authors": "Kunej Tanja, Wang Zeping, Michal Jennifer J, Daniels Tyler F, Magnuson Nancy S, Jiang Zhihua", "evidence": [ { "database": "RefSeq", "id": "NP_777054", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_777054" } ], "reference": [ { "type": "PubMed", "id": "18198295", "url": "https://glygen.org/publication/PubMed/18198295" } ] } ], "pathway": [ { "id": "bta:282393", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?bta:282393", "resource": "KEGG Pathway" }, { "id": "R-BTA-611105", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-BTA-611105", "resource": "Reactome", "description": "Respiratory electron transport" }, { "id": "R-BTA-9865881", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-BTA-9865881", "resource": "Reactome", "description": "Complex III assembly" } ], "orthologs": [ { "uniprot_canonical_ac": "P31930-1", "protein_name": "Cytochrome b-c1 complex subunit 1, mitochondrial", "gene_name": "UQCRC1", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MAASVVCRAATAGAQVLLRARRSPALLRTPALRSTATFAQALQFVPETQVSLLDNGLRVASEQSSQPTCTVGVWIDVGSRFETEKNNGAGYFLEHLAFKGTKNRPGSALEKEVESMGAHLNAYSTREHTAYYIKALSKDLPKAVELLGDIVQNCSLEDSQIEKERDVILREMQENDASMRDVVFNYLHATAFQGTPLAQAVEGPSENVRKLSRADLTEYLSTHYKAPRMVLAAAGGVEHQQLLDLAQKHLGGIPWTYAEDAVPTLTPCRFTGSEIRHRDDALPFAHVAIAVEGPGWASPDNVALQVANAIIGHYDCTYGGGVHLSSPLASGAVANKLCQSFQTFSICYAETGLLGAHFVCDRMKIDDMMFVLQGQWMRLCTSATESEVARGKNILRNALVSHLDGTTPVCEDIGRSLLTYGRRIPLAEWESRIAEVDASVVREICSKYIYDQCPAVAGYGPIEQLPDYNRIRSGMFWLRF", "length": 480 }, "evidence": [ { "id": "G1K1X0", "url": "https://omabrowser.org/oma/group/G1K1X0/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "Q68FY0-1", "protein_name": "Cytochrome b-c1 complex subunit 1, mitochondrial", "gene_name": "Uqcrc1", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MAASAVCRAACSGTQALLRTCRSPALLRLPALRGTATFVQALQSVPETQVSVLDNGLRVASEQSSHPTCTVGVWIDVGSRYETEKNNGAGYFLEHLAFKGTKNRPGNALEKEVESIGAHLNAYSTREHTAYLIKALSKDLPKVVELLADIVQNISLEDSQIEKERDVILREMQENDASMQNVVFDYLHATAFQGTPLAQAVEGPSENVRRLSRTDLTDYLSRHYKAPRMVLAAAGGVKHQQLLDLAQDHFSSVSQVYEEDAVPSITPCRFTGSEIRHRDDALPLAHVAIAVEGPGWANPDNVALQVANAIIGHYDCTYGGGVHLSSPLASVAVANKLCQSFQTFNISYSETGLLGAHFVCDAMSIDDMIFFLQGQWMRLCTSATESEVTRGKNILRNALISHLDGTTPVCEDIGRSLLTYGRRIPLAEWESRIEEVDAQMVREVCSKYFYDQCPAVAGYGPIEQLSDYNRIRSGMFWLRF", "length": 480 }, "evidence": [ { "id": "G1K1X0", "url": "https://omabrowser.org/oma/group/G1K1X0/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "Q9CZ13-1", "protein_name": "Cytochrome b-c1 complex subunit 1, mitochondrial", "gene_name": "Uqcrc1", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MAASAVCRAACSGTQVLLRTRRSPALLRLPALRGTATFAQALQSVPETQVSILDNGLRVASEQSSHATCTVGVWIDAGSRYETEKNNGAGYFLEHLAFKGTKNRPGNALEKEVESIGAHLNAYSTREHTAYLIKALSKDLPKVVELLADIVQNSSLEDSQIEKERDVILREMQENDASMQNVVFDYLHATAFQGTPLAQAVEGPSENVRRLSRTDLTDYLNRHYKAPRMVLAAAGGVEHQQLLDLAQKHLSSVSRVYEEDAVPGLTPCRFTGSEIRHRDDALPLAHVAIAVEGPGWANPDNVTLQVANAIIGHYDCTYGGGVHLSSPLASVAVANKLCQSFQTFNISYSDTGLLGAHFVCDAMSIDDMVFFLQGQWMRLCTSATESEVTRGKNILRNALVSHLDGTTPVCEDIGRSLLTYGRRIPLAEWESRIQEVDAQMLRDICSKYFYDQCPAVAGYGPIEQLPDYNRIRSGMFWLRF", "length": 480 }, "evidence": [ { "id": "G1K1X0", "url": "https://omabrowser.org/oma/group/G1K1X0/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" } ], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 3, "go_terms": [ { "name": "mitochondrial inner membrane", "id": "GO:0005743", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005743", "evidence": [ { "database": "UniProtKB", "id": "G1K1X0", "url": "https://www.uniprot.org/uniprotkb/G1K1X0" } ], "pmid": "" }, { "name": "respiratory chain complex III", "id": "GO:0045275", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0045275", "evidence": [ { "database": "UniProtKB", "id": "G1K1X0", "url": "https://www.uniprot.org/uniprotkb/G1K1X0" } ], "pmid": "" }, { "name": "mitochondrial processing peptidase complex", "id": "GO:0017087", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0017087", "evidence": [ { "database": "UniProtKB", "id": "G1K1X0", "url": "https://www.uniprot.org/uniprotkb/G1K1X0" } ], "pmid": "" } ] }, { "name": "Molecular Function", "total": 2, "go_terms": [ { "name": "metal ion binding", "id": "GO:0046872", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0046872", "evidence": [ { "database": "UniProtKB", "id": "G1K1X0", "url": "https://www.uniprot.org/uniprotkb/G1K1X0" } ], "pmid": "" }, { "name": "ubiquitin protein ligase binding", "id": "GO:0031625", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0031625", "evidence": [ { "database": "UniProtKB", "id": "G1K1X0", "url": "https://www.uniprot.org/uniprotkb/G1K1X0" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 2, "go_terms": [ { "name": "respiratory electron transport chain", "id": "GO:0022904", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0022904", "evidence": [ { "database": "UniProtKB", "id": "G1K1X0", "url": "https://www.uniprot.org/uniprotkb/G1K1X0" } ], "pmid": "" }, { "name": "protein processing involved in protein targeting to mitochondrion", "id": "GO:0006627", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006627", "evidence": [ { "database": "UniProtKB", "id": "G1K1X0", "url": "https://www.uniprot.org/uniprotkb/G1K1X0" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 153, "end_pos": 155, "annotation": "n_glycosylation_sequon" }, { "start_pos": 175, "end_pos": 177, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], 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regulating the fusion of zymogen granules with each other. 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"database": "UniProtKB", "id": "G3MWH7", "url": "https://www.uniprot.org/uniprotkb/G3MWH7" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 1, "go_terms": [ { "name": "zymogen granule membrane", "id": "GO:0042589", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0042589", "evidence": [ { "database": "UniProtKB", "id": "G3MWH7", "url": "https://www.uniprot.org/uniprotkb/G3MWH7" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [ { "pdb_id": "AF-G3MWH7-F1", "pdb_chain": "global", "start_pos": 1, "end_pos": 134, "overlap": "1.0", "method": "AlphaFold", "type": "alphafold", "resolution": -1.0, "url": "https://data.glygen.org/ln2downloads/pdb/current/AF-G3MWH7-F1.pdb", "url_external": "https://alphafold.ebi.ac.uk/entry/G3MWH7" } ], "lectin_list": [], "domain_list": [], "binding_sites": [], "synthesized_glycans": 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"start_pos": 64696125, "end_pos": 64703948, "strand": "+", "evidence": [ { "database": "Ensembl Gene", "id": "ENSBTAG00000047395", "url": "https://www.ensembl.org/id/ENSBTAG00000047395" } ] } } ], "crossref": [ { "id": "G3MWJ4", "url": "https://alphafold.ebi.ac.uk/entry/G3MWJ4", "database": "AlphaFoldDB", "categories": [] }, { "id": "ENSBTAG00000047395", "url": "https://bgee.org/?page=gene&gene_id=ENSBTAG00000047395", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "100300920", "url": "https://www.ncbi.nlm.nih.gov/gene/100300920", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR002125", "url": "https://www.ebi.ac.uk/interpro/entry/IPR002125", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR038953", "url": "https://www.ebi.ac.uk/interpro/entry/IPR038953", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "bta:100300920", "url": "https://www.genome.jp/dbget-bin/www_bget?bta:100300920", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "PASAWNR", "url": "https://omabrowser.org/oma/group/PASAWNR/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "G3MWJ4", "url": "https://www.orthodb.org/?gene=G3MWJ4", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR35672", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR35672", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR35672:SF1", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR35672:SF1", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF18775", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF18775", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "R-BTA-72200", "url": "https://www.reactome.org/PathwayBrowser/#R-BTA-72200", "database": 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"length": 367, "header": "tr|G3MWJ4-1|G3MWJ4_BOVIN Isoform 1 of Apolipoprotein B mRNA editing enzyme catalytic polypeptide like 4 OS=Bos taurus OX=9913 GN=APOBEC4 PE=4 SV=1 CANONICAL=G3MWJ4-1" }, "isoforms": [ { "isoform_ac": "G3MWJ4-1", "url": "https://www.uniprot.org/uniprotkb/G3MWJ4/entry", "sequence": { "sequence": "MEPLYEEYLANHGTIVKPYYWLSFSLDCSNCPYHIRTGEEARVPYTEFYQIFGFPYGPTYPPTKHLTFYELKTSSGSLVQKGHASSCTGNDTHPESMLFEVNGYFDSAIHNNDCIRHIILYSSNSPCNEANHCCISKMYTFLAKYPDITLSVYFSQLYHTEAEFPASPWNREALRSLASLWPQVTLSPISGGIWYSLLSNFVSGVQGASVFQPILTGRALADRHNAHEINAITGVKPYFTDVLLQAEENPDVKVQAALEGHPLNSVFPRQSFQVTSGQLQPNLTLDPRVPVVFVLVPYRDLPPIHVGPSPHKPRNIIRHLNVPQVSFQETGDLRKSPIGMPVERVEITGQFASSKEADEKKKKKAKN", "length": 367, "header": "tr|G3MWJ4-1|G3MWJ4_BOVIN Isoform 1 of Apolipoprotein B mRNA editing enzyme catalytic polypeptide like 4 OS=Bos taurus OX=9913 GN=APOBEC4 PE=4 SV=1 CANONICAL=G3MWJ4-1" }, "locus": { "chromosome": "16", "start_pos": 64697393, "end_pos": 64696293, "strand": "+", "evidence": [ { 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"overlap": "1.0", "method": "AlphaFold", "type": "alphafold", "resolution": -1.0, "url": "https://data.glygen.org/ln2downloads/pdb/current/AF-G3MWJ4-F1.pdb", "url_external": "https://alphafold.ebi.ac.uk/entry/G3MWJ4" } ], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "G3MWJ4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3MWJ4" }, { "id": "PS51747", "database": "PROSITE", "url": "https://prosite.expasy.org/PS51747" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "CMP/dCMP-type deaminase", "eco_id": "ECO_0000259", "start_pos": 61, "end_pos": 177, "start_aa": "Pro", "end_aa": "Leu", "glycosite_overlap": [] } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "homologset.oma", "label": "OMA Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { 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"id": "G3MWK0", "url": "https://alphafold.ebi.ac.uk/entry/G3MWK0", "database": "AlphaFoldDB", "categories": [] }, { "id": "ENSBTAG00000018906", "url": "https://bgee.org/?page=gene&gene_id=ENSBTAG00000018906", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "788008", "url": "https://www.ncbi.nlm.nih.gov/gene/788008", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR031516", "url": "https://www.ebi.ac.uk/interpro/entry/IPR031516", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "bta:788008", "url": "https://www.genome.jp/dbget-bin/www_bget?bta:788008", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "VDINKML", "url": "https://omabrowser.org/oma/group/VDINKML/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "G3MWK0", "url": "https://www.orthodb.org/?gene=G3MWK0", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR37867", "url": 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"MDSAGAEKRPGAQEGIAVGQSQLTEVAGGHAQNSECPVMRDQCLVPAHESCQTQGEDKCPIRSTSEQKIQERLKLEEDRHKPEVEALEERGPRPMASTVRPSHGPKRKPVSLFPSLAGPSHQAHPRAESELPQGLLLQREEPENNQSEPSPTAKQHKKAKKRKSLGTPVLPVVASTVSAPSVTLGPERKAQRLRPLYQYINYCNPELNQAGEGDREAEAEVEPESELTMVPEEAGVEKLQALLPVAGELGSDLTLPCPSMSVPPTHTLVPLGEEASEEPEGLPSLGVSGCLKAEMDKSTQVDINKMLSVCNAPLVPPLSPQYK", "length": 323, "header": "tr|G3MWK0-1|G3MWK0_BOVIN Isoform 1 of Chromosome 18 C16orf86 homolog OS=Bos taurus OX=9913 GN=C18H16orf86 PE=4 SV=2 CANONICAL=G3MWK0-1" }, "isoforms": [ { "isoform_ac": "G3MWK0-1", "url": "https://www.uniprot.org/uniprotkb/G3MWK0/entry", "sequence": { "sequence": "MDSAGAEKRPGAQEGIAVGQSQLTEVAGGHAQNSECPVMRDQCLVPAHESCQTQGEDKCPIRSTSEQKIQERLKLEEDRHKPEVEALEERGPRPMASTVRPSHGPKRKPVSLFPSLAGPSHQAHPRAESELPQGLLLQREEPENNQSEPSPTAKQHKKAKKRKSLGTPVLPVVASTVSAPSVTLGPERKAQRLRPLYQYINYCNPELNQAGEGDREAEAEVEPESELTMVPEEAGVEKLQALLPVAGELGSDLTLPCPSMSVPPTHTLVPLGEEASEEPEGLPSLGVSGCLKAEMDKSTQVDINKMLSVCNAPLVPPLSPQYK", "length": 323, "header": "tr|G3MWK0-1|G3MWK0_BOVIN Isoform 1 of Chromosome 18 C16orf86 homolog OS=Bos taurus OX=9913 GN=C18H16orf86 PE=4 SV=2 CANONICAL=G3MWK0-1" }, "locus": { "chromosome": "18", "start_pos": 35222029, "end_pos": 35220376, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000064305.3", "url": "https://www.ensembl.org/id/ENSBTAT00000064305.3" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000053901.2", "url": "https://www.ensembl.org/id/ENSBTAP00000053901.2" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [ { "id": "bta:788008", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?bta:788008", "resource": "KEGG Pathway" } ], "orthologs": [ { "uniprot_canonical_ac": "A0A9J7FJJ4-1", "protein_name": "Uncharacterized protein C16orf86 homolog isoform X1", "gene_name": "CUNH16orf86", "tax_id": 10029, "organism": "Cricetulus griseus", "sequence": { "sequence": 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"MASAGAKRQPEAQNGAAVGLAQVAEIPECPGTEECLVPAHETCSTPGEDRCPVGHSLEPELQEEGINLGEEGLNPGVEAGEERGPKPTSSIVRPAHGPKRKAEAELPPGLLLQKEEPEGSHSESSLSSKQHKKAKKRKSVGAPVPPAVASASAPTETLGLEPFAVPWVLAGKAQRLRPLYQYINYCNPELNQAGDGDREPEAEPESELALAPEEAGVEQLQLQTLLPMAGELGLGLALPCPNPLAPLTHNLPPLVEEVGEEPGGLSSLRVSGSLKAEVDKTTQVDIDKMLSVCAAPLVPPLSPQYK", "length": 306 }, "evidence": [ { "id": "G3MWK0", "url": "https://omabrowser.org/oma/group/G3MWK0/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "I3LHH2-1", "protein_name": "Chromosome 6 C16orf86 homolog", "gene_name": "C6H16orf86", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MASAGDERRPGTQEKTAVGLAQLTEVPTDQCLEPALVACQTQGEDKCPTGAVSEPELLEERLKMEEKRLKPVAEALEERGPRPITSIVKPNHGPKRKAEAELPQGLLLQKEELENSQSEPSPSAKQHKKAKKRKSLGTPVLPVVASTVSVPSETLGLEPPALLWVLAGKAQRLRPLYQYINYCNPELNQAGEGDREAEAEVEPEVELTLVPEEAGVEQLQALLPMAGELGPGLTLPCPNMFVCPAHPLVPLGEEAGEESGGLPSLGVSSHLKAEVDKSTHVDINKMLSVCAAPLVPPLSPQYK", "length": 303 }, "evidence": [ { "id": "G3MWK0", "url": "https://omabrowser.org/oma/group/G3MWK0/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "Q6ZW13-1", "protein_name": "Uncharacterized protein C16orf86", "gene_name": "C16orf86", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MASAGAERRPGVQEATVVGQGQLTEEPGSAQTSECPVAGDQFLVPAHEARGTQSEDQRPAGAASESELQEEGPKLGEERPKPHAGALEERGPRPVVSIVRPRHGPKRKPVKSLSLPGLRAHLKAEAELPPKLPLQEEEPEDSQSEPSPSAKQHKKAKKRKSLGAPVLHAVASMVSAPLETLRLERKAQRLRPLYQYVNYCNPELNQAGKGDGEAEVEAEAELAPVPEEGGVEQLQALLPLAGELGPGLALPCPSPLVTPTHALAPLGEEAGEEPGGLPSLGVSDHKAEVDKSTQVDIDKMLSVCTAPLVPPLSPQYK", "length": 317 }, "evidence": [ { "id": "G3MWK0", "url": "https://omabrowser.org/oma/group/G3MWK0/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "Q9D4A5-1", "protein_name": "Uncharacterized protein C16orf86 homolog", "gene_name": "", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MASEGAKRQPETQNGAAVGLAQVAESLECPGTEECLVPAHETCRSPGEDKCPVGHSLEPELQEEGIKVGEEGLNAGVEAGEERGPKPTSSIVRPAHGPKRKSEVELPPGVLQKKEEPEGSHSESSLSSKQHKKAKKRKSGGAPVPPAVASASAPAAETLGLEPFALPWVLAGKAQRLRPLYQYINYCNPELNQEEDGDREPEVEPEAELALVPEEPGVEQLQLQTLLPVAGELGLGLALPCPNPLVPLTHNLPPLVEEVGEEPGGLSSLRVSGSLKAEVDKTTQVDIDKMLSVCAAPLVPPLSPQYK", "length": 307 }, "evidence": [ { "id": "G3MWK0", "url": "https://omabrowser.org/oma/group/G3MWK0/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" } ], "go_annotation": {}, "pro_annotation": [], "site_annotation": [ { "start_pos": 145, "end_pos": 147, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [ { "pdb_id": "AF-G3MWK0-F1", "pdb_chain": "global", "start_pos": 1, "end_pos": 323, "overlap": "1.0", "method": "AlphaFold", "type": "alphafold", "resolution": -1.0, "url": 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"publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ], "tool_support": { "graph_view": "yes" } }, { "uniprot_canonical_ac": "G3MWM1-1", "uniprot_ac": "G3MWM1", "uniprot_id": "G3MWM1_BOVIN", "mass": { "chemical_mass": 53976.0, "monoisotopic_mass": 53976.0 }, "refseq": {}, "gene_names": [ { "name": "KLF11", "type": "recommended", "evidence": [ { "id": "G3MWM1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3MWM1" } ] } ], "protein_names": [ { "name": "KLF transcription factor 11", "type": "synonym", "evidence": [ { "id": "G3MWM1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3MWM1/entry#names_and_taxonomy" } ] } ], "function": [], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Bos taurus", "taxid": 9913, "evidence": [ { "database": "UniProtKB", "id": "G3MWM1", "url": "https://www.uniprot.org/uniprotkb/G3MWM1" } ], "common_name": "Bovine", "glygen_name": "Bovine", "reference_species": "Bos taurus [9913]" } ], "gene": [ { "name": "KLF11", "url": "https://www.uniprot.org/uniprotkb/G3MWM1", "locus": { "chromosome": "11", "start_pos": 87547144, "end_pos": 87558865, "strand": "+", "evidence": [ { "database": "Ensembl Gene", "id": "ENSBTAG00000046218", "url": "https://www.ensembl.org/id/ENSBTAG00000046218" } ] } } ], "crossref": [ { "id": "G3MWM1", "url": "https://alphafold.ebi.ac.uk/entry/G3MWM1", "database": "AlphaFoldDB", "categories": [] }, { "id": "ENSBTAG00000046218", "url": "https://bgee.org/?page=gene&gene_id=ENSBTAG00000046218", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "cd21584", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd21584", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "616730", "url": "https://www.ncbi.nlm.nih.gov/gene/616730", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR013087", "url": "https://www.ebi.ac.uk/interpro/entry/IPR013087", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR036236", "url": "https://www.ebi.ac.uk/interpro/entry/IPR036236", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "QSCAPQM", "url": "https://omabrowser.org/oma/group/QSCAPQM/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "A0A3Q1LSF2", "url": "https://www.orthodb.org/?gene=A0A3Q1LSF2", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "G3MWM1", "url": "https://www.orthodb.org/?gene=G3MWM1", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR23235", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR23235", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR23235:SF65", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR23235:SF65", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00096", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00096", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "A0A3Q1LSF2", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1LSF2", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A3Q1LSF2-1", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1LSF2-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "G3MWM1", "url": "https://www.uniprot.org/uniprotkb/G3MWM1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "G3MWM1-1", "url": "https://www.uniprot.org/uniprotkb/G3MWM1-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MDICESILERKRHDSERSTCSILEQNDMEAVEALVCMSSWGQRSQKADLLNIRPLTPVSDSGDVTTSVHVDTVPSELPKDFHSLSTLCMTPPQSPDLLEPLTGTVVPPQVTASKAPVVMAVPQASAGAARVLNRTAEGGLPGPKPELLEPAASFPCRATVTGITGHAGGSPTSAHHSCPTAQTQEHQLSACTEGEAQFLGHVETLQDMHLTDSLLSMNSVSCQPCLHKSSGLIPTNKGQQAGWPIGIQTCSPKNYDNDLARKATPLISIPIPSPPVLCQMIPVTGSSGLLPAVLKPPPQVSAGLVKPVLPHAAPALPPVFVGTSVPQGTMMLLLPQGALPQPTTCSAGNMPVGNTRFLPLAPAPVFIASSQSCAPQVDFSRRRNYVCHFPGCRKTYFKSSHLKAHLRTHTGEKPFGCSWDGCNKKFARSDELSRHRRTHTGEKKFVCPVCDRRFMRSDHLTKHARRHMATKRVPGWQAAVGRLNRAASAEDPGSPLEPECAPASA", "length": 505, "header": "tr|G3MWM1-1|G3MWM1_BOVIN Isoform 1 of KLF transcription factor 11 OS=Bos taurus OX=9913 GN=KLF11 PE=3 SV=1 CANONICAL=G3MWM1-1" }, "isoforms": [ { "isoform_ac": "A0A3Q1LSF2-1", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1LSF2/entry", "sequence": { "sequence": "MHTPGSAGPGDAPRVVDIMDICESILERKRHDSERSTCSILEQNDMEAVEALVCMSSWGQRSQKADLLNIRPLTPVSDSGDVTTSVHVDTVPSELPKDFHSLSTLCMTPPQSPDLLEPLTGTVVPPQVTASKAPVVMAVPQASAGAARVLNRTAEGGLPGPKPELLEPAASFPCRATVTGITGHAGGSPTSAHHSCPTAQTQEHQLSACTEGEAQFLGHVETLQDMHLTDSLLSMNSVSCQPCLHKSSGLIPTNKGQQAGWPIGIQTCSPKNYDNDLARKATPLISIPIPSPPVLCQMIPVTGSSGLLPAVLKPPPQVSAGLVKPVLPHAAPALPPVFVGTSVPQGTMMLLLPQGALPQPTTCSAGNMPVGNTRFLPLAPAPVFIASSQSCAPQVDFSRRRNYVCHFPGCRKTYFKSSHLKAHLRTHTGEKPFGCSWDGCNKKFARSDELSRHRRTHTGEKKFVCPVCDRRFMRSDHLTKHARRHMATKRVPGWQAAVGRLNRAASAEDPGSPLEPECAPASA", "length": 523, "header": "tr|A0A3Q1LSF2-1|A0A3Q1LSF2_BOVIN Computationally mapped isoform of KLF transcription factor 11 OS=Bos taurus OX=9913 GN=KLF11 PE=3 SV=1 CANONICAL=G3MWM1-1" }, "locus": { "chromosome": "11", "start_pos": 87558666, "end_pos": 87549525, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000080078.2", "url": "https://www.ensembl.org/id/ENSBTAT00000080078.2" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000063288.1", "url": "https://www.ensembl.org/id/ENSBTAP00000063288.1" } ] } }, { "isoform_ac": "G3MWM1-1", "url": "https://www.uniprot.org/uniprotkb/G3MWM1/entry", "sequence": { "sequence": "MDICESILERKRHDSERSTCSILEQNDMEAVEALVCMSSWGQRSQKADLLNIRPLTPVSDSGDVTTSVHVDTVPSELPKDFHSLSTLCMTPPQSPDLLEPLTGTVVPPQVTASKAPVVMAVPQASAGAARVLNRTAEGGLPGPKPELLEPAASFPCRATVTGITGHAGGSPTSAHHSCPTAQTQEHQLSACTEGEAQFLGHVETLQDMHLTDSLLSMNSVSCQPCLHKSSGLIPTNKGQQAGWPIGIQTCSPKNYDNDLARKATPLISIPIPSPPVLCQMIPVTGSSGLLPAVLKPPPQVSAGLVKPVLPHAAPALPPVFVGTSVPQGTMMLLLPQGALPQPTTCSAGNMPVGNTRFLPLAPAPVFIASSQSCAPQVDFSRRRNYVCHFPGCRKTYFKSSHLKAHLRTHTGEKPFGCSWDGCNKKFARSDELSRHRRTHTGEKKFVCPVCDRRFMRSDHLTKHARRHMATKRVPGWQAAVGRLNRAASAEDPGSPLEPECAPASA", "length": 505, "header": "tr|G3MWM1-1|G3MWM1_BOVIN Isoform 1 of KLF transcription factor 11 OS=Bos taurus OX=9913 GN=KLF11 PE=3 SV=1 CANONICAL=G3MWM1-1" }, "locus": { "chromosome": "11", "start_pos": 87556534, "end_pos": 87549525, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000066246.2", "url": "https://www.ensembl.org/id/ENSBTAT00000066246.2" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000053923.1", "url": "https://www.ensembl.org/id/ENSBTAP00000053923.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [], "orthologs": [ { "uniprot_canonical_ac": "A0A8V0X9Z8-1", "protein_name": "Kruppel like factor 11", "gene_name": "KLF11", "tax_id": 9031, "organism": "Gallus gallus", "sequence": { "sequence": "METLLQSAVPPGRDRGWEHRAGSPKCVDIVDIYESIRERQRHDSERSTCSTLEQNDIEAVEALVCMSSWGQRLQKGDILKIRPLTPFSDSGDFTMHAEAASELPKDCLSTLCMTPPHSPDLVEMSAAVLLPSQVTYSKPRTVMANTAACLLTSTTDATPAAKPSVLSVERQCEQRAEASAPQPCRAMATSVIRHTGDSSAYHHGAAVREKAKAASGCGTSGDRRGAEGRRRPGLPQDACAADAFISKASPVPQPCAADCSDVVPSKGQLPVRPVSPQAHLPKSCKDDLQRRATPVTPVPVSSPQVLCQMIPLNGQSGVINAYVKPSAPAVSAPMKPILPQAAPLSQPVLVGSSVPQGAVMLVLPQTAVAPTPQCPQTVMTVGNTKLLPLAPAPMFIASGQSCTPQMDFSRRRNYVCNFPGCKKTYFKSSHLKAHLRTHTGEKPFSCNWEGCDKKFARSDELSRHRRTHTGEKKFACPVCERRFMRSDHLTKHTRRHMATKKVPSWQTEVGKLNRMATAEKPKGSGALSMLIPVPSPVCQG", "length": 540 }, "evidence": [ { "id": "G3MWM1", "url": "https://omabrowser.org/oma/group/G3MWM1/", "database": "OMA" } ], "glygen_name": "Chicken", "common_name": "Chicken" }, { "uniprot_canonical_ac": "E9PTS6-1", "protein_name": "KLF transcription factor 11", "gene_name": "Klf11", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MHSPGSTGPGDARAADIMDICESILERKRHDSERSTCSILEQTDIEAVEALVCMSSWGQRSQVRPLTPVSDSGDVTTAVLMDTAAPDLPKDFHSFSTLCITPPQSPELMEPTGTPVPSQVINSQGCMATALPPSPTGGPRTLSKGEPPEPSSESSCRAVMTSVIRHTGESPAPTCFPTGPTQEQPASDSRGGQDPLLDHLEALQDTRLADGLLVTNLVSCQPCLHKSGGLFPIDKGQQTVWPTAVQTCLPKNPESDLSRKTTPFISVPVSSPPVLCQMIPVAGQNGMLSAFLRPPTQLPAGTIKPILPQAASMSQPVFMGPPVPQGTVMLVLPQSTFPQPAACPSSVMAIGNTKLLPLAPAPVFVASSQNCAPQVDFSRRRNYVCNFPGCRKTYFKSSHLKAHLRTHTGEKPFTCSWDGCDKKFARSDELSRHRRTHTGEKKFVCPVCDRRFMRSDHLTKHARRHMTTKKIPGWQAEVGKLNRITLAESPRSILEPLPASG", "length": 501 }, "evidence": [ { "id": "G3MWM1", "url": "https://omabrowser.org/oma/group/G3MWM1/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "O14901-1", "protein_name": "Krueppel-like factor 11", "gene_name": "KLF11", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MHTPDFAGPDDARAVDIMDICESILERKRHDSERSTCSILEQTDMEAVEALVCMSSWGQRSQKGDLLRIRPLTPVSDSGDVTTTVHMDAATPELPKDFHSLSTLCITPPQSPDLVEPSTRTPVSPQVTDSKACTATDVLQSSAVVARALSGGAERGLLGLEPVPSSPCRAKGTSVIRHTGESPAACFPTIQTPDCRLSDSREGEEQLLGHFETLQDTHLTDSLLSTNLVSCQPCLHKSGGLLLTDKGQQAGWPGAVQTCSPKNYENDLPRKTTPLISVSVPAPPVLCQMIPVTGQSSMLPAFLKPPPQLSVGTVRPILAQAAPAPQPVFVGPAVPQGAVMLVLPQGALPPPAPCAANVMAAGNTKLLPLAPAPVFITSSQNCVPQVDFSRRRNYVCSFPGCRKTYFKSSHLKAHLRTHTGEKPFNCSWDGCDKKFARSDELSRHRRTHTGEKKFVCPVCDRRFMRSDHLTKHARRHMTTKKIPGWQAEVGKLNRIASAESPGSPLVSMPASA", "length": 512 }, "evidence": [ { "id": "G3MWM1", "url": "https://omabrowser.org/oma/group/G3MWM1/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" } ], "go_annotation": { "categories": [ { "name": "Molecular Function", "total": 4, "go_terms": [ { "name": "DNA binding", "id": "GO:0003677", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003677", "evidence": [ { "database": "UniProtKB", "id": "G3MWM1", "url": "https://www.uniprot.org/uniprotkb/G3MWM1" } ], "pmid": "" }, { "name": "zinc ion binding", "id": "GO:0008270", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008270", "evidence": [ { "database": "UniProtKB", "id": "G3MWM1", "url": "https://www.uniprot.org/uniprotkb/G3MWM1" } ], "pmid": "" }, { "name": "RNA polymerase II cis-regulatory region sequence-specific DNA binding", "id": "GO:0000978", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000978", "evidence": [ { "database": "UniProtKB", "id": "G3MWM1", "url": "https://www.uniprot.org/uniprotkb/G3MWM1" } ], "pmid": "" }, { "name": "DNA-binding transcription factor activity, RNA polymerase II-specific", "id": "GO:0000981", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000981", "evidence": [ { "database": "UniProtKB", "id": "G3MWM1", "url": "https://www.uniprot.org/uniprotkb/G3MWM1" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 2, "go_terms": [ { "name": "nucleus", "id": "GO:0005634", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005634", "evidence": [ { 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"url": "https://www.genome.jp/dbget-bin/www_bget?bta:112445077", "resource": "KEGG Pathway" } ], "orthologs": [ { "uniprot_canonical_ac": "A0A286ZSK5-1", "protein_name": "Uncharacterized protein", "gene_name": "", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MAKVSRKPREPRTAVTQSTRRIKRKKTLSKPRSRGGVKAPKTTMKIKRALRRNLRRKIQTSAGQPKKAKKARKHFVSYYVLKKSGQNKKTNQNKRQNQNKRQNQNKRRGQPVPEQEIMEKPTTSCKWCSQGVTRRGRRY", "length": 139 }, "evidence": [ { "id": "G3MWR3", "url": "https://omabrowser.org/oma/group/G3MWR3/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "Q09821-1", "protein_name": "Spermatid nuclear transition protein 4", "gene_name": "TNP4", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "AKVSRKPREPRTAVTQSTRRIKRKKTLSKPRSRGGVKAPKTTMKIKRALRRNLRRKIQTSAGQPKKAKKARKHFVSYYVLKKSGQNKKTNQNKRQNQNKRQNQNKRRGQPVPEQEIMEKPTTSCKWCSQGVTRRGRRY", "length": 138 }, "evidence": [ { "id": "G3MWR3", "url": 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"https://www.ensembl.org/id/ENSBTAG00000038659" } ] } } ], "crossref": [ { "id": "G3MWZ7", "url": "https://alphafold.ebi.ac.uk/entry/G3MWZ7", "database": "AlphaFoldDB", "categories": [] }, { "id": "ENSBTAG00000038659", "url": "https://bgee.org/?page=gene&gene_id=ENSBTAG00000038659", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "cd18396", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd18396", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "cd22218", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd22218", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "IPR000210", "url": "https://www.ebi.ac.uk/interpro/entry/IPR000210", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR003131", "url": "https://www.ebi.ac.uk/interpro/entry/IPR003131", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR011333", "url": "https://www.ebi.ac.uk/interpro/entry/IPR011333", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR049904", "url": "https://www.ebi.ac.uk/interpro/entry/IPR049904", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR057093", "url": "https://www.ebi.ac.uk/interpro/entry/IPR057093", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "DNPPNAQ", "url": "https://omabrowser.org/oma/group/DNPPNAQ/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "G3MWZ7", "url": "https://www.orthodb.org/?gene=G3MWZ7", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR14499", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR14499", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR14499:SF68", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR14499:SF68", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF02214", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF02214", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF23110", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF23110", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "G3MWZ7", "url": "https://www.uniprot.org/uniprotkb/G3MWZ7", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "G3MWZ7-1", "url": "https://www.uniprot.org/uniprotkb/G3MWZ7-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MALKDTGSGGGTILPISEMVSSSSSPGASSAATPGPCVPSPFPEVVELNVGGQVYVTKHSTLLSVPDSTLASMFSPSSPRGGARRRGELPRDSRARFFIDRDGFLFRYVLDYLRDKQLALPEHFPEKERLLREAEYFQLTDLVKLLSPKVTKQNSLNDEGCQSDLEDNVSQGSSDALLLRGAAAAAPSGPGAHSSGSAQDKRSGFLTLGYRGSYTTVRDNQADAKFRRVARIMVCGRIALAKEVFGDTLNESRDPDRPPEKYTSRFYLKFTYLEQAFDRLSEAGFHMVACNSSGTAAFVNQYRDDKIWSSYTEYIFFRPPQKIVSPKQEHEDRKHDKVTDKGSESGTSCNELSTSSCDSHSEASTPQDNPPSAQQATAHQPNTLTLDRPSKKAPVQWMPPPDKRRNSELFQTLISKSRETNLSKKKVCEKLSVEEEMKKCIQDFKKIHIPDYFPERKRQWQSELLQKYGL", "length": 470, "header": "tr|G3MWZ7-1|G3MWZ7_BOVIN Isoform 1 of Potassium channel tetramerization domain containing 8 OS=Bos taurus OX=9913 GN=KCTD8 PE=4 SV=2 CANONICAL=G3MWZ7-1" }, "isoforms": [ { "isoform_ac": "G3MWZ7-1", "url": "https://www.uniprot.org/uniprotkb/G3MWZ7/entry", "sequence": { "sequence": "MALKDTGSGGGTILPISEMVSSSSSPGASSAATPGPCVPSPFPEVVELNVGGQVYVTKHSTLLSVPDSTLASMFSPSSPRGGARRRGELPRDSRARFFIDRDGFLFRYVLDYLRDKQLALPEHFPEKERLLREAEYFQLTDLVKLLSPKVTKQNSLNDEGCQSDLEDNVSQGSSDALLLRGAAAAAPSGPGAHSSGSAQDKRSGFLTLGYRGSYTTVRDNQADAKFRRVARIMVCGRIALAKEVFGDTLNESRDPDRPPEKYTSRFYLKFTYLEQAFDRLSEAGFHMVACNSSGTAAFVNQYRDDKIWSSYTEYIFFRPPQKIVSPKQEHEDRKHDKVTDKGSESGTSCNELSTSSCDSHSEASTPQDNPPSAQQATAHQPNTLTLDRPSKKAPVQWMPPPDKRRNSELFQTLISKSRETNLSKKKVCEKLSVEEEMKKCIQDFKKIHIPDYFPERKRQWQSELLQKYGL", "length": 470, "header": "tr|G3MWZ7-1|G3MWZ7_BOVIN Isoform 1 of Potassium channel tetramerization domain containing 8 OS=Bos taurus OX=9913 GN=KCTD8 PE=4 SV=2 CANONICAL=G3MWZ7-1" }, "locus": { "chromosome": "6", "start_pos": 63097599, "end_pos": 62835531, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000051902.4", "url": "https://www.ensembl.org/id/ENSBTAT00000051902.4" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000054055.2", "url": "https://www.ensembl.org/id/ENSBTAP00000054055.2" } ] } } ], "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "other", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 33, "start_aa": "Thr", "end_pos": 33, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr33", "evidence": [ { "id": "", "database": "GlyGen", "url": "https://data.glygen.org/" } ], "filter_code": "000000000000000010000.00000000001000.0.01000" } ], "phosphorylation": [], "glycation": [], "keywords": [ "glycoprotein", "glycoprotein_predicted" ], "publication": [], "pathway": [], "orthologs": [ { "uniprot_canonical_ac": "A6Y7S3-1", "protein_name": "Potassium channel tetramerization domain containing 8", "gene_name": "Kctd8", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MALKDTGSGGSTILPISEMVSASSSPGAPLAAAPGPCAPSPFPEVVELNVGGQVYVTKHSTLLSVPDSTLASMFSPSSPRGGARRRGDLPRDSRARFFIDRDGFLFRYVLDYLRDKQLALPEHFPEKERLLREAEFFQLTDLVKLLSPKVTKQNSLNDEGCQSDLEDNLSQGSSDALLLRGAAAGAPSSSGAHGVSGVVSGGSAPDKRSGFLTLGYRGSYTTVRDNQADAKFRRVARIMVCGRIALAKEVFGDTLNESRDPDRQPEKYTSRFYLKFTYLEQAFDRLSEAGFHMVACNSSGTAAFVNQYRDDKIWSSYTEYIFFRPPQKIVSPKQEHEDRKCDKVTDKGSESGTSCNELSTSSCDSHSEASTPQDNLVNTQQAVSQQPNTLTLDRPSRKAPVQWMPPPDKRRNSELFQSLISKSRETNLSKKKVCEKLSVEEEMKKCIQDFKKIHIPDCFPERKRQWQSELLQKYGL", "length": 476 }, "evidence": [ { "id": "G3MWZ7", "url": "https://omabrowser.org/oma/group/G3MWZ7/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "F1NX81-1", "protein_name": "Potassium channel tetramerization domain containing 8", "gene_name": "KCTD8", "tax_id": 9031, "organism": "Gallus gallus", "sequence": { "sequence": "MALKEAGGSILPISDMVSGPSGSPFPEVVELNVGGQVYVTRHSTLLSVPDSTLATMFSPCRGGPAAARQLPRDSRARFFIDRDGFLFRYVLDYLRDKQLALPEHFPEKERLLREAEYFQLGDLVKLLSPKVTKQSSLNDEGCQSDLEDSTSQGSSDRLQRAGLDKRSGFLTVGYRGSYTTVRDNQADAKFRRVARIMVCGRIALAKEVFGETLNESRDPDRPPEKYTSRFYLKFTYLEQAFDRLSEAGFHMVACNSTGTAAFINQYRDDKIWSSYTEYIFFRPPQRTVSPKQDHEERKHDKVLDKGSESGTSCNELSTSSCDSHSDASTPQENASGTQQSTAHQPNTLTLDRPSKKAPVQWMPPPDKRRNSELFQTLISKSRETNLSKKKVCEKLSVEEEMRKCIQDFKKIHIPDYFPERKRPWQSELLQKYGL", "length": 434 }, "evidence": [ { "id": "G3MWZ7", "url": "https://omabrowser.org/oma/group/G3MWZ7/", "database": "OMA" } ], "glygen_name": "Chicken", "common_name": "Chicken" }, { "uniprot_canonical_ac": "Q50H33-1", "protein_name": "BTB/POZ domain-containing protein KCTD8", "gene_name": "Kctd8", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MALKDTGSGGSTILPISEMVSASSSPGAPLAAAPGPCAPSPFPEVVELNVGGQVYVTKHSTLLSVPDSTLASMFSPSSPRGGARRRGDLPRDSRARFFIDRDGFLFRYVLDYLRDKQLALPEHFPEKERLLREAEFFQLTDLVKLLSPKVTKQNSLNDECCQSDLEDNVSQGSSDALLLRGAAAGAPSGSGAHGVSGVVGGGSAPDKRSGFLTLGYRGSYTTVRDNQADAKFRRVARIMVCGRIALAKEVFGDTLNESRDPDRQPEKYTSRFYLKFTYLEQAFDRLSEAGFHMVACNSSGTAAFVNQYRDDKIWSSYTEYIFFRPPQKIVSPKQEHEDRKRDKVTDKGSESGTSCNELSTSSCDSHSEASTPQDNPANTQQAAAHQPNTLTLDRPSRKAPVQWMPPPDKRRNSELFQSLISKSRETNLSKKKVCEKLSVEEEMKKCIQDFKKIHIPDCFPERKRQWQSELLQKYGL", "length": 476 }, "evidence": [ { "id": "G3MWZ7", "url": "https://omabrowser.org/oma/group/G3MWZ7/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q6ZWB6-1", "protein_name": "BTB/POZ domain-containing protein KCTD8", "gene_name": "KCTD8", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MALKDTGSGGSTILPISEMVSSSSSPGASAAAAPGPCAPSPFPEVVELNVGGQVYVTKHSTLLSVPDSTLASMFSPSSPRGGARRRGELPRDSRARFFIDRDGFLFRYVLDYLRDKQLALPEHFPEKERLLREAEYFQLTDLVKLLSPKVTKQNSLNDEGCQSDLEDNVSQGSSDALLLRGAAAAVPSGPGAHGGGGGGGAQDKRSGFLTLGYRGSYTTVRDNQADAKFRRVARIMVCGRIALAKEVFGDTLNESRDPDRQPEKYTSRFYLKFTYLEQAFDRLSEAGFHMVACNSSGTAAFVNQYRDDKIWSSYTEYIFFRPPQKIVSPKQEHEDRKHDKVTDKGSESGTSCNELSTSSCDSHSEASTPQDNPSSAQQATAHQPNTLTLDRPSKKAPVQWIPPPDKRRNSELFQTLISKSRETNLSKKKVCEKLSVEEEMKKCIQDFKKIHIPDYFPERKRQWQSELLQKYGL", "length": 473 }, "evidence": [ { "id": "G3MWZ7", "url": "https://omabrowser.org/oma/group/G3MWZ7/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" } ], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 3, "go_terms": [ { "name": "presynaptic active zone membrane", "id": "GO:0048787", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0048787", "evidence": [ { "database": "UniProtKB", "id": "G3MWZ7", "url": "https://www.uniprot.org/uniprotkb/G3MWZ7" } ], "pmid": "" }, { "name": "receptor complex", "id": "GO:0043235", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0043235", "evidence": [ { "database": "UniProtKB", "id": "G3MWZ7", "url": "https://www.uniprot.org/uniprotkb/G3MWZ7" } ], "pmid": "" }, { "name": "postsynaptic membrane", "id": "GO:0045211", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0045211", "evidence": [ { "database": "UniProtKB", "id": "G3MWZ7", "url": "https://www.uniprot.org/uniprotkb/G3MWZ7" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 2, "go_terms": [ { "name": "protein homooligomerization", "id": "GO:0051260", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0051260", "evidence": [ { "database": "UniProtKB", "id": "G3MWZ7", "url": "https://www.uniprot.org/uniprotkb/G3MWZ7" } ], "pmid": "" }, { "name": "regulation of G protein-coupled receptor signaling pathway", "id": "GO:0008277", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008277", "evidence": [ { "database": "UniProtKB", "id": "G3MWZ7", "url": "https://www.uniprot.org/uniprotkb/G3MWZ7" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 168, "end_pos": 170, "annotation": "n_glycosylation_sequon" }, { "start_pos": 250, "end_pos": 252, "annotation": "n_glycosylation_sequon" }, { "start_pos": 291, "end_pos": 293, "annotation": "n_glycosylation_sequon" }, { "start_pos": 421, "end_pos": 423, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [ { "pdb_id": "AF-G3MWZ7-F1", "pdb_chain": "global", "start_pos": 1, "end_pos": 470, "overlap": "1.0", "method": "AlphaFold", "type": "alphafold", "resolution": -1.0, "url": "https://data.glygen.org/ln2downloads/pdb/current/AF-G3MWZ7-F1.pdb", "url_external": "https://alphafold.ebi.ac.uk/entry/G3MWZ7" } ], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "G3MWZ7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3MWZ7" }, { "id": "SM00225", "database": "SMART", "url": "http://smart.embl.de/smart/do_annotation.pl?DOMAIN=SM00225" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "BTB", "eco_id": "ECO_0000259", "start_pos": 44, "end_pos": 154, "start_aa": "Glu", "end_aa": "Asn", "glycosite_overlap": [] } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "homologset.oma", "label": "OMA Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [ 33 ], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 168, "end_pos": 170 }, { "start_pos": 250, "end_pos": 252 }, { "start_pos": 291, "end_pos": 293 }, { "start_pos": 421, "end_pos": 423 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 1 }, { "field": "total_sites", "count": 1 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 1 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "exact_sites", "count": 1 }, { "field": "exact_o_linked_sites", "count": 1 }, { "field": "fuzzy_sites", "count": 0 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_pos", "start_aa", "end_pos", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 1 }, { "field": "total_sites", "count": 1 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 1 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "exact_sites", "count": 1 }, { "field": "exact_o_linked_sites", "count": 1 }, { "field": "fuzzy_sites", "count": 0 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_pos", "start_aa", "end_pos", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ], "tool_support": { "graph_view": "yes" } }, { "uniprot_canonical_ac": "G3MX02-1", "uniprot_ac": "G3MX02", "uniprot_id": "G3MX02_BOVIN", "mass": { "chemical_mass": 12641.0, "monoisotopic_mass": 12641.0 }, "refseq": {}, "gene_names": [], "protein_names": [ { "name": "WAP domain-containing protein", "type": "recommended", "evidence": [ { "id": "G3MX02", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3MX02/entry#names_and_taxonomy" } ] } ], "function": [], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Bos 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"IPR001841", "url": "https://www.ebi.ac.uk/interpro/entry/IPR001841", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR013083", "url": "https://www.ebi.ac.uk/interpro/entry/IPR013083", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR017907", "url": "https://www.ebi.ac.uk/interpro/entry/IPR017907", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR040100", "url": "https://www.ebi.ac.uk/interpro/entry/IPR040100", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR051435", "url": "https://www.ebi.ac.uk/interpro/entry/IPR051435", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "bta:100299353", "url": "https://www.genome.jp/dbget-bin/www_bget?bta:100299353", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "IVNQYVV", "url": "https://omabrowser.org/oma/group/IVNQYVV/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "G3MX21", "url": "https://www.orthodb.org/?gene=G3MX21", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR22791", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR22791", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR22791:SF3", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR22791:SF3", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "XP_024855454", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_024855454", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "G3MX21", "url": "https://www.uniprot.org/uniprotkb/G3MX21", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "G3MX21-1", "url": "https://www.uniprot.org/uniprotkb/G3MX21-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MPADPGPEVGGGWPGFLMSCLKGPHVILKMEAMKMVHPEKFPELQAATPCFPPAPRPAPALAPKRAWPSDTEIIVNQACGGDMPALEGAPCTPPLPRRPRKGSAELGFPRVAPADEVIVNQYVIRPSPAAPGAPAAAVAAAAGEPLECPTCGHTYNATQRRPRVLSCLHSVCEQCLQILYESCPKYKFISCPTCRRETVLFTDYGLAALAINTSILSRLPPEALTAPSGGQWGGEPEGSCYQTFRQYCGAACTCHARNPLSACSIM", "length": 266, "header": "tr|G3MX21-1|G3MX21_BOVIN Isoform 1 of RING finger protein 208 OS=Bos taurus OX=9913 GN=RNF208 PE=4 SV=1 CANONICAL=G3MX21-1" }, "isoforms": [ { "isoform_ac": "G3MX21-1", "url": "https://www.uniprot.org/uniprotkb/G3MX21/entry", "sequence": { "sequence": "MPADPGPEVGGGWPGFLMSCLKGPHVILKMEAMKMVHPEKFPELQAATPCFPPAPRPAPALAPKRAWPSDTEIIVNQACGGDMPALEGAPCTPPLPRRPRKGSAELGFPRVAPADEVIVNQYVIRPSPAAPGAPAAAVAAAAGEPLECPTCGHTYNATQRRPRVLSCLHSVCEQCLQILYESCPKYKFISCPTCRRETVLFTDYGLAALAINTSILSRLPPEALTAPSGGQWGGEPEGSCYQTFRQYCGAACTCHARNPLSACSIM", "length": 266, "header": "tr|G3MX21-1|G3MX21_BOVIN Isoform 1 of RING finger protein 208 OS=Bos taurus OX=9913 GN=RNF208 PE=4 SV=1 CANONICAL=G3MX21-1" }, "locus": { "chromosome": "11", "start_pos": 106237133, "end_pos": 106236336, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000066282.3", "url": "https://www.ensembl.org/id/ENSBTAT00000066282.3" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000054080.1", "url": "https://www.ensembl.org/id/ENSBTAP00000054080.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [ { "id": "bta:100299353", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?bta:100299353", "resource": "KEGG Pathway" } ], "orthologs": [ { "uniprot_canonical_ac": "A0A3L7HFG4-1", "protein_name": "RING finger protein 208", "gene_name": "Rnf208", "tax_id": 10029, "organism": "Cricetulus griseus", "sequence": { "sequence": "MPADPGPEVGSGWPGLLMSCLKGPHVILKMEAMKIVHPEKFPELPAATPCFPPAPRPTPTLAPKRAWPSDTEIIVNQACGGDMPTLEGAPHTPPLPRRPRKGSSELGFPRVAPVDEVIVNQYVIRPGPTASAPSSSGPVIAGEPLECPTCGHTYNVTQRRPRVLSCLHSVCEQCLQILYESCPKYKFISCPTCHRETVLFTDYGLAALAVNTSILSRLPPEALTAPSGGQWGGESEGSCYQTFRQYCGAACTCHVRNPLSACSIM", "length": 265 }, "evidence": [ { "id": "G3MX21", "url": "https://omabrowser.org/oma/group/G3MX21/", "database": "OMA" } ], "glygen_name": "Hamster", "common_name": "Chinese hamster" }, { "uniprot_canonical_ac": "A0A8V1AKT6-1", "protein_name": "Ring finger protein 208", "gene_name": "RNF208", "tax_id": 9031, "organism": "Gallus gallus", "sequence": { "sequence": "MLPACCSLMQASFGDPRAVDSNVKTILMSCLKGQQVIIKMEAMKIIHPEKFSELQAAPPRYAPAPRREPPLVAKRAWPSESEIIVNQACGDIPALDATPAPLPLPRTPPLPRRERGYQGQRKGSSEVCFHRQPPSDEVIVNQYVLHPSTPCEPLECPTCGHMYNFTNKRPRILSCLHSVCEECLQILYESCPKYKFISCPTCKRETVLFTDYGLAALAVNTSILNRLPAEALAANPVQWSSDTDRSCYQTFRQYCGAACTCHIRNPLSSCTIM", "length": 273 }, "evidence": [ { "id": "G3MX21", "url": "https://omabrowser.org/oma/group/G3MX21/", "database": "OMA" } ], "glygen_name": "Chicken", "common_name": "Chicken" }, { "uniprot_canonical_ac": "D4ADR3-1", "protein_name": "RING finger protein 208", "gene_name": "Rnf208", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MPADPGPEVGSGWPGLLMSCLKGPHVILKMEAMKIVHPEKFPELPAATPCFPPAPRPTPTLAPKRAWPSDTEIIVNQACGGDMPTLEGASHTPPLPRRPRKGSSELGFPRVAPVDEVIVNQYVIRPGPTASAPSSSGPVIAGEPLECPTCGHTYNVTQRRPRVLSCLHSVCEQCLQILYESCPKYKFISCPTCHRETVLFTDYGLAALAVNTSILSRLPPEALTAPSGGQWGGESEGSCYQTFRQYCGAACTCHVRNPLSACSIM", "length": 265 }, "evidence": [ { "id": "G3MX21", "url": "https://omabrowser.org/oma/group/G3MX21/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "Q8K0W3-1", "protein_name": "RING finger protein 208", "gene_name": "Rnf208", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MPADPGPEVGSGWPGLLMSCLKGPHVILKMEAMKIVHPEKFPELPAATPCFPPAPRPTPTLAPKRAWPSDTEIIVNQACGGDMPTLEGASHTPPLPRRPRKGSSELGFPRVAPVDEVIVNQYVIRPGPTASAPSSSGPVIAGEPLECPTCGHTYNVTQRRPRVLSCLHSVCEQCLQILYESCPKYKFISCPTCHRETVLFTDYGLAALAVNTSILSRLPPEALTAPSGGQWGGESEGSCYQTFRQYCGAACTCHVRNPLSACSIM", "length": 265 }, "evidence": [ { "id": "G3MX21", "url": "https://omabrowser.org/oma/group/G3MX21/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q9H0X6-1", "protein_name": "RING finger protein 208", "gene_name": "RNF208", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MPSDPGPEAGSGWPGLLMSCLKGPHVILKMEAMKIVHPEKFPELPAAPCFPPAPRPTPTLAPKRAWPSDTEIIVNQACGGDMPALEGAPHTPPLPRRPRKGSSELGFPRVAPEDEVIVNQYVIRPGPSASAASSAAAGEPLECPTCGHSYNVTQRRPRVLSCLHSVCEQCLQILYESCPKYKFISCPTCRRETVLFTDYGLAALAVNTSILSRLPPEALTAPSGGQWGAEPEGSCYQTFRQYCGAACTCHVRNPLSACSIM", "length": 261 }, "evidence": [ { "id": "G3MX21", "url": "https://omabrowser.org/oma/group/G3MX21/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" } ], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 1, "go_terms": [ { "name": "nucleoplasm", "id": "GO:0005654", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005654", "evidence": [ { "database": "UniProtKB", "id": "G3MX21", "url": "https://www.uniprot.org/uniprotkb/G3MX21" } ], "pmid": "" } ] }, { "name": "Molecular Function", "total": 2, "go_terms": [ { "name": "zinc ion binding", "id": "GO:0008270", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008270", "evidence": [ { "database": "UniProtKB", "id": "G3MX21", "url": "https://www.uniprot.org/uniprotkb/G3MX21" } ], "pmid": "" }, { "name": "ubiquitin protein ligase activity", "id": "GO:0061630", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0061630", "evidence": [ { "database": "UniProtKB", "id": "G3MX21", "url": "https://www.uniprot.org/uniprotkb/G3MX21" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 2, "go_terms": [ { "name": "protein ubiquitination", "id": "GO:0016567", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016567", "evidence": [ { "database": "UniProtKB", "id": "G3MX21", "url": "https://www.uniprot.org/uniprotkb/G3MX21" } ], "pmid": "" }, { "name": "protein autoubiquitination", "id": "GO:0051865", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0051865", "evidence": [ { "database": "UniProtKB", "id": "G3MX21", "url": "https://www.uniprot.org/uniprotkb/G3MX21" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 156, "end_pos": 158, "annotation": "n_glycosylation_sequon" }, { "start_pos": 212, "end_pos": 214, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [ { "pdb_id": "AF-G3MX21-F1", "pdb_chain": "global", "start_pos": 1, "end_pos": 266, "overlap": "1.0", "method": "AlphaFold", "type": "alphafold", "resolution": -1.0, "url": "https://data.glygen.org/ln2downloads/pdb/current/AF-G3MX21-F1.pdb", "url_external": "https://alphafold.ebi.ac.uk/entry/G3MX21" } ], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "G3MX21", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3MX21" }, { "id": "PS50089", "database": "PROSITE", "url": "https://prosite.expasy.org/PS50089" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "RING-type", "eco_id": "ECO_0000259", "start_pos": 148, "end_pos": 195, "start_aa": "Cys", "end_aa": "Arg", "glycosite_overlap": [] } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "homologset.oma", "label": "OMA Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 156, "end_pos": 158 }, { "start_pos": 212, "end_pos": 214 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ], "tool_support": { "graph_view": "yes" } }, { "uniprot_canonical_ac": "G3MX25-1", "uniprot_ac": "G3MX25", "uniprot_id": "G3MX25_BOVIN", "mass": { "chemical_mass": 17963.0, "monoisotopic_mass": 17963.0 }, "refseq": { "ac": "XP_002690524", "name": "uncharacterized protein C15orf61 homolog", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_002690524" }, "gene_names": [ { "name": "C10H15orf61", "type": "recommended", "evidence": [ { "id": "G3MX25", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3MX25" } ] }, { "name": "C10H15orf61", "type": "synonym", "evidence": [ { "id": "XP_002690524", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_002690524" } ] } ], "protein_names": [ { "name": "Chromosome 10 C15orf61 homolog", "type": "synonym", "evidence": [ { "id": "G3MX25", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3MX25/entry#names_and_taxonomy" } ] }, { "name": "uncharacterized protein C15orf61 homolog", "type": "synonym", "evidence": [ { "id": "XP_002690524", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_002690524" } ] } ], "function": [], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Bos taurus", "taxid": 9913, "evidence": [ { "database": "UniProtKB", "id": "G3MX25", "url": "https://www.uniprot.org/uniprotkb/G3MX25" } ], "common_name": "Bovine", "glygen_name": "Bovine", "reference_species": "Bos taurus [9913]" } ], "gene": [ { "name": "C10H15orf61", "url": "https://www.uniprot.org/uniprotkb/G3MX25", "locus": { "chromosome": "10", "start_pos": 14362718, "end_pos": 14357444, "strand": "-", "evidence": [ { "database": "Ensembl Gene", "id": "ENSBTAG00000045628", "url": "https://www.ensembl.org/id/ENSBTAG00000045628" } ] } } ], "crossref": [ { "id": "G3MX25", "url": "https://alphafold.ebi.ac.uk/entry/G3MX25", "database": "AlphaFoldDB", "categories": [] }, { "id": "ENSBTAG00000045628", "url": "https://bgee.org/?page=gene&gene_id=ENSBTAG00000045628", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "535251", "url": "https://www.ncbi.nlm.nih.gov/gene/535251", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR029245", "url": "https://www.ebi.ac.uk/interpro/entry/IPR029245", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "bta:535251", "url": "https://www.genome.jp/dbget-bin/www_bget?bta:535251", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "KYHCTRR", "url": "https://omabrowser.org/oma/group/KYHCTRR/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "G3MX25", "url": "https://www.orthodb.org/?gene=G3MX25", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR34651", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR34651", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR34651:SF1", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR34651:SF1", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF15031", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF15031", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "XP_002690524", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_002690524", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "G3MX25", "url": "https://www.uniprot.org/uniprotkb/G3MX25", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "G3MX25-1", "url": "https://www.uniprot.org/uniprotkb/G3MX25-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MEALRRAHEAVLRLLLCRPWAAGAASRPKPRASEVLTRHLLQRRLPHWTSFCVPYSAVRNDQFGLSHFNWPVQGANYHVLRTGCFPFIKYHCSKAPWQDLAGQDRFFTALKVVNLGIPTLLYGLGSWLFARVTETVHTSYGPITVYFLNKEDEGAMY", "length": 157, "header": "tr|G3MX25-1|G3MX25_BOVIN Isoform 1 of Chromosome 10 C15orf61 homolog OS=Bos taurus OX=9913 GN=C10H15orf61 PE=4 SV=2 CANONICAL=G3MX25-1" }, "isoforms": [ { "isoform_ac": "G3MX25-1", "url": "https://www.uniprot.org/uniprotkb/G3MX25/entry", "sequence": { "sequence": "MEALRRAHEAVLRLLLCRPWAAGAASRPKPRASEVLTRHLLQRRLPHWTSFCVPYSAVRNDQFGLSHFNWPVQGANYHVLRTGCFPFIKYHCSKAPWQDLAGQDRFFTALKVVNLGIPTLLYGLGSWLFARVTETVHTSYGPITVYFLNKEDEGAMY", "length": 157, "header": "tr|G3MX25-1|G3MX25_BOVIN Isoform 1 of Chromosome 10 C15orf61 homolog OS=Bos taurus OX=9913 GN=C10H15orf61 PE=4 SV=2 CANONICAL=G3MX25-1" }, "locus": { "chromosome": "10", "start_pos": 14362612, "end_pos": 14357643, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000066309.4", "url": "https://www.ensembl.org/id/ENSBTAT00000066309.4" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000054084.2", "url": "https://www.ensembl.org/id/ENSBTAP00000054084.2" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [ { "id": "bta:535251", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?bta:535251", "resource": "KEGG Pathway" } ], "orthologs": [ { "uniprot_canonical_ac": "A0ABK0LKW0-1", "protein_name": "Similar to human chromosome 15 open reading frame 61", "gene_name": "C8h15orf61", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MEPLRRAHEAMLRLLLWGPWASGAASRPKPRASEVLTRHLLQRRLPHWTSFCVPYSAVHNDQFGLSHFNWPVPGANYHVLRTGCFPFIKYHCSKAPWQDLAAQNRFFTALKVINMGEWRPDRGTLPAQGGRWPTSTPLGFQGQFFASPPGCLQHP", "length": 155 }, "evidence": [ { "id": "G3MX25", "url": "https://omabrowser.org/oma/group/G3MX25/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "A4V381-1", "protein_name": "Uncharacterized protein", "gene_name": "Dmel\\CG34148", "tax_id": 7227, "organism": "Drosophila melanogaster", "sequence": { "sequence": "MQLTRLLLKPRASEVLTAYLKQCHEPPWTSYFVKFHDVANDQRGMSHFNWTLENGTNYHILRTACYPYMKYHCSKREVQDLWLEDKFFRFLKVINLGLPMLFYGLAAIRLISHTEIVHVSETVKVPIYFLYPEDKGSSF", "length": 139 }, "evidence": [ { "id": "G3MX25", "url": "https://omabrowser.org/oma/group/G3MX25/", "database": "OMA" } ], "glygen_name": "Fruit fly", "common_name": "Fruit fly" }, { "uniprot_canonical_ac": "A6NNL5-1", "protein_name": "Uncharacterized protein C15orf61", "gene_name": "C15orf61", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MEALRRAHEVALRLLLCRPWASRAAARPKPSASEVLTRHLLQRRLPHWTSFCVPYSAVRNDQFGLSHFNWPVQGANYHVLRTGCFPFIKYHCSKAPWQDLARQNRFFTALKVVNLGIPTLLYGLGSWLFARVTETVHTSYGPITVYFLNKEDEGAMY", "length": 157 }, "evidence": [ { "id": "G3MX25", "url": "https://omabrowser.org/oma/group/G3MX25/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "F1NUQ7-1", "protein_name": "Chromosome 15 open reading frame 61", "gene_name": "C15orf61", "tax_id": 9031, "organism": "Gallus gallus", "sequence": { "sequence": "MQALRRLHEAVLGLLLWGRAASARPDASEVLSQHLRQRGLPHWTSYCVKYSAVRNDQFGLSHFNWRVDGANYHILRTGCFPFVKYHCSRAAPQDLALQNAAFTALKVLNAGIPTLLYGIGSWFFVSVTETVHTSRGPVTIYFLNKEDEGAMY", "length": 152 }, "evidence": [ { "id": "G3MX25", "url": "https://omabrowser.org/oma/group/G3MX25/", "database": "OMA" } ], "glygen_name": "Chicken", "common_name": "Chicken" }, { "uniprot_canonical_ac": "F1SJI8-1", "protein_name": "Chromosome 1 C15orf61 homolog", "gene_name": "C1H15orf61", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MEALRRAHEAVLRLLLFRPWASDAASRLKPRASEVLTRHLLQRRLPHWTSFCVPYSAVRNDQFGLSHFNWPVQGANYHVLRTGCFPFIKYHCSKAPWQDLARQDRFFTALKVINLGIPTLLYGLGSWLFARVTETVHTSYGPITVYFLNKEDEGAMY", "length": 157 }, "evidence": [ { "id": "G3MX25", "url": "https://omabrowser.org/oma/group/G3MX25/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "G3H8P5-1", "protein_name": "Uncharacterized protein C15orf61 homolog", "gene_name": "CUNH15orf61", "tax_id": 10029, "organism": "Cricetulus griseus", "sequence": { "sequence": "MEALRRAHEVVLRLLLCRSWALGAASRPKPRASEVLTLHLVQRRLPHWTSFCVPYSAVHNDQFGLSHFNWPVPGANYHVLRTGCFPFIKYHCSKAPWQDLAPQNRFFTALKVINLGIPTLLYGLGSWLFARVTETVHTSYGPITIYFLNKEDEGAMY", "length": 157 }, "evidence": [ { "id": "G3MX25", "url": "https://omabrowser.org/oma/group/G3MX25/", "database": "OMA" } ], "glygen_name": "Hamster", "common_name": "Chinese hamster" }, { "uniprot_canonical_ac": "Q0VG49-1", "protein_name": "Uncharacterized protein C15orf61 homolog", "gene_name": "", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MEALRRAHEATLRLLLCRPWASGAASRPKPRASEVLTQHLLQRRLPHWTSFCVPYSAVHNDQFGLSHFNWPVLGANYHVLRTGCFPFIKYHCSKAPWQDLAPQDRFFTALKVINLGIPTLLYGLGSWLFARVTETVHTSYGPITIYFLNKEDEGAMY", "length": 157 }, "evidence": [ { "id": "G3MX25", "url": "https://omabrowser.org/oma/group/G3MX25/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" } ], "go_annotation": {}, "pro_annotation": [], "site_annotation": [], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [ { "pdb_id": "AF-G3MX25-F1", "pdb_chain": "global", "start_pos": 1, "end_pos": 157, "overlap": "1.0", "method": "AlphaFold", "type": "alphafold", "resolution": -1.0, "url": "https://data.glygen.org/ln2downloads/pdb/current/AF-G3MX25-F1.pdb", "url_external": "https://alphafold.ebi.ac.uk/entry/G3MX25" } ], "lectin_list": [], "domain_list": [], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "homologset.oma", "label": "OMA Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ], "tool_support": { "graph_view": "yes" } }, { "uniprot_canonical_ac": "G3MX45-1", "uniprot_ac": "G3MX45", "uniprot_id": "G3MX45_BOVIN", "mass": { "chemical_mass": 14393.0, "monoisotopic_mass": 14393.0 }, "refseq": {}, "gene_names": [], "protein_names": [ { "name": "Large ribosomal subunit protein eL31", "type": "recommended", "evidence": [ { "id": "G3MX45", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3MX45/entry#names_and_taxonomy" } ] }, { "name": "60S ribosomal protein L31", "type": "synonym", "evidence": [ { "id": "G3MX45", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3MX45/entry#names_and_taxonomy" } ] } ], "function": [ { "annotation": "Component of the large ribosomal subunit. The ribosome is a large ribonucleoprotein complex responsible for the synthesis of proteins in the cell.", "evidence": [ { "database": "UniProtKB", "id": "G3MX45", "url": "https://www.uniprot.org/uniprotkb/G3MX45#function" }, { "database": "UniProtKB", "id": "ARBA00034092", "url": "https://www.uniprot.org/uniprotkb/ARBA00034092#function" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Bos taurus", "taxid": 9913, "evidence": [ { "database": "UniProtKB", "id": "G3MX45", "url": "https://www.uniprot.org/uniprotkb/G3MX45" } ], "common_name": "Bovine", "glygen_name": "Bovine", "reference_species": "Bos taurus [9913]" } ], "gene": [ { "name": "", "url": "https://www.uniprot.org/uniprotkb/G3MX45", "locus": {} } ], "crossref": [ { "id": "G3MX45", "url": "https://alphafold.ebi.ac.uk/entry/G3MX45", "database": "AlphaFoldDB", "categories": [] }, { "id": "ENSBTAG00000046820", "url": "https://bgee.org/?page=gene&gene_id=ENSBTAG00000046820", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "cd00463", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd00463", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "IPR000054", "url": "https://www.ebi.ac.uk/interpro/entry/IPR000054", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR023621", "url": "https://www.ebi.ac.uk/interpro/entry/IPR023621", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "EVWKQGI", "url": "https://omabrowser.org/oma/group/EVWKQGI/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "PTHR10956", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR10956", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR10956:SF41", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR10956:SF41", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF01198", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF01198", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "G3MX45", "url": "https://www.uniprot.org/uniprotkb/G3MX45", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "G3MX45-1", "url": "https://www.uniprot.org/uniprotkb/G3MX45-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MAPAKKGGKKKGWSAINEMVIREYTINIHKRIHGVGFKKHAPRALKDIWKFTMKEMGTPDVHIDTRLNKAIWAQGIRNDAYRIRVQLSRKRNEDEDSPNKLYTLVTYVPVTTFKDLQTVNVDEN", "length": 124, "header": "tr|G3MX45-1|G3MX45_BOVIN Isoform 1 of Large ribosomal subunit protein eL31 OS=Bos taurus OX=9913 GN= PE=3 SV=1 CANONICAL=G3MX45-1" }, "isoforms": [ { "isoform_ac": "G3MX45-1", "url": "https://www.uniprot.org/uniprotkb/G3MX45/entry", "sequence": { "sequence": "MAPAKKGGKKKGWSAINEMVIREYTINIHKRIHGVGFKKHAPRALKDIWKFTMKEMGTPDVHIDTRLNKAIWAQGIRNDAYRIRVQLSRKRNEDEDSPNKLYTLVTYVPVTTFKDLQTVNVDEN", "length": 124, "header": "tr|G3MX45-1|G3MX45_BOVIN Isoform 1 of Large ribosomal subunit protein eL31 OS=Bos taurus OX=9913 GN= PE=3 SV=1 CANONICAL=G3MX45-1" }, "locus": { "chromosome": "X", "start_pos": 57711474, "end_pos": 57711103, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000064020.2", "url": "https://www.ensembl.org/id/ENSBTAT00000064020.2" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000054104.1", "url": "https://www.ensembl.org/id/ENSBTAP00000054104.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [], "orthologs": [ { "uniprot_canonical_ac": "G3HHK3-1", "protein_name": "Large ribosomal subunit protein eL31", "gene_name": "Rpl31", "tax_id": 10029, "organism": "Cricetulus griseus", "sequence": { "sequence": "MAPAKKGGEKKKGRSAINEVVTREYTINIHKRIHGVGFKKRAPRALKEIRKFAMKEMGTPDVRIDTRLNKAVWAKGIRNVPYRIRVRLSRKRNEDEDSPNKLYTLVTYVPVTTFKNLQTVNVDEN", "length": 125 }, "evidence": [ { "id": "G3MX45", "url": "https://omabrowser.org/oma/group/G3MX45/", "database": "OMA" } ], "glygen_name": "Hamster", "common_name": "Chinese hamster" }, { "uniprot_canonical_ac": "P0C2H9-1", "protein_name": "Large ribosomal subunit protein eL31B", "gene_name": "RPL31B", "tax_id": 559292, "organism": "Saccharomyces cerevisiae S288C", "sequence": { "sequence": "MAGLKDVVTREYTINLHKRLHGVSFKKRAPRAVKEIKKFAKLHMGTEDVRLAPELNQAIWKRGVKGVEYRLRLRISRKRNEEEDAKNPLFSYVEPVLVASAKGLQTVVVEEDA", "length": 113 }, "evidence": [ { "id": "G3MX45", "url": "https://omabrowser.org/oma/group/G3MX45/", "database": "OMA" } ], "glygen_name": "Yeast", "common_name": "Baker's yeast" }, { "uniprot_canonical_ac": "P62899-1", "protein_name": "Large ribosomal subunit protein eL31", "gene_name": "RPL31", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MAPAKKGGEKKKGRSAINEVVTREYTINIHKRIHGVGFKKRAPRALKEIRKFAMKEMGTPDVRIDTRLNKAVWAKGIRNVPYRIRVRLSRKRNEDEDSPNKLYTLVTYVPVTTFKNLQTVNVDEN", "length": 125 }, "evidence": [ { "id": "G3MX45", "url": "https://omabrowser.org/oma/group/G3MX45/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "P62900-1", "protein_name": "Large ribosomal subunit protein eL31", "gene_name": "Rpl31", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MAPAKKGGEKKKGRSAINEVVTREYTINIHKRIHGVGFKKRAPRALKEIRKFAMKEMGTPDVRIDTRLNKAVWAKGIRNVPYRIRVRLSRKRNEDEDSPNKLYTLVTYVPVTTFKNLQTVNVDEN", "length": 125 }, "evidence": [ { "id": "G3MX45", "url": "https://omabrowser.org/oma/group/G3MX45/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "P62901-1", "protein_name": "Large ribosomal subunit protein eL31", "gene_name": "RPL31", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MAPAKKGGEKKKGRSAINEVVTREYTINIHKRIHGVGFKKRAPRALKEIRKFAMKEMGTPDVRIDTRLNKAVWAKGIRNVPYRIRVRLSRKRNEDEDSPNKLYTLVTYVPVTTFKNLQTVNVDEN", "length": 125 }, "evidence": [ { "id": "G3MX45", "url": "https://omabrowser.org/oma/group/G3MX45/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "P62902-1", "protein_name": "Large ribosomal subunit protein eL31", "gene_name": "Rpl31", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MAPAKKGGEKKKGRSAINEVVTREYTINIHKRIHGVGFKKRAPRALKEIRKFAMKEMGTPDVRIDTRLNKAVWAKGIRNVPYRIRVRLSRKRNEDEDSPNKLYTLVTYVPVTTFKNLQTVNVDEN", "length": 125 }, "evidence": [ { "id": "G3MX45", "url": "https://omabrowser.org/oma/group/G3MX45/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "Q54XB5-1", "protein_name": "Large ribosomal subunit protein eL31", "gene_name": "rpl31", "tax_id": 44689, "organism": "Dictyostelium discoideum", "sequence": { "sequence": "MSSSEAVTREYTINLHKRLYGTTFKDRAPKAVKQVKLFAQKIMGTKDVRIDNKLNKFLWSQGIKNVPHRVRVTLSRKRNEDENATEKLYTVASLVIVKSFKGLQTKKVADN", "length": 111 }, "evidence": [ { "id": "G3MX45", "url": "https://omabrowser.org/oma/group/G3MX45/", "database": "OMA" } ], "glygen_name": "Cellular slime mold", "common_name": "Social amoeba" }, { "uniprot_canonical_ac": "Q9STR1-1", "protein_name": "Large ribosomal subunit protein eL31y", "gene_name": "RPL31B", "tax_id": 3702, "organism": "Arabidopsis thaliana", "sequence": { "sequence": "MSEKKGRKEEVVTREYTINLHRRLHSCTFKKKAPKAIKEIRKFAEKEMGTKDVRVDVKLNKQIWSKGIRGPPRRIRVRVARKRNDDEDAKEEFFSLVTVAEIPAEGLSGLGTKIIEEED", "length": 119 }, "evidence": [ { "id": "G3MX45", "url": "https://omabrowser.org/oma/group/G3MX45/", "database": "OMA" } ], "glygen_name": "Arabidopsis", "common_name": "Mouse-ear cress" }, { "uniprot_canonical_ac": "Q9V597-1", "protein_name": "Large ribosomal subunit protein eL31", "gene_name": "RpL31", "tax_id": 7227, "organism": "Drosophila melanogaster", "sequence": { "sequence": "MTKTKGEKINKSAINEVVTRECTIHLAKRVHNIGFKKRAPRAIKEIRKFAEREMGTTDVRIDTRLNKHIWSKGIRSTPFRIRVRLARRRNDDEDSPNKLYTYVTYVPVSTFKNLQTENVESSDD", "length": 124 }, "evidence": [ { "id": "G3MX45", "url": "https://omabrowser.org/oma/group/G3MX45/", "database": "OMA" } ], "glygen_name": "Fruit fly", "common_name": "Fruit fly" } ], "go_annotation": { "categories": [ { "name": "Biological Process", "total": 1, "go_terms": [ { "name": "cytoplasmic translation", "id": "GO:0002181", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0002181", "evidence": [ { "database": "UniProtKB", "id": "G3MX45", "url": "https://www.uniprot.org/uniprotkb/G3MX45" } ], "pmid": "" } ] }, { "name": "Molecular Function", "total": 1, "go_terms": [ { "name": "structural constituent of ribosome", "id": "GO:0003735", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003735", "evidence": [ { "database": "UniProtKB", "id": "G3MX45", "url": "https://www.uniprot.org/uniprotkb/G3MX45" } ], "pmid": "" } ] }, { "name": "Cellular 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"categories": [ "Protein Classification", "Other" ] }, { "id": "NP_001193798", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001193798", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "G3MXA3", "url": "https://www.uniprot.org/uniprotkb/G3MXA3", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "G3MXA3-1", "url": "https://www.uniprot.org/uniprotkb/G3MXA3-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MAARPGPLWLLGLALCALSGGGIPGPRPPLGCPQRRLGPRERRDLQREILAVLGLPGRPRPRAPPAAALLPASAPLFMLDLYRAVADDDDEDGGAPERRLGRADLVMSFVNMVERDPALGHQEPHWKEFHFDLTQIPAGEAVTAAEFRIYKLPSTHPLNQTLHISMFEVVPEQSNRESDLFFLDLQTLRSGDEGWLVLDVTAASDRWLLSRNKDLGLRLYVETDDGRSVDPGLAGLLGRQAPRSKQPFVVTFFRASPGPGPARAPRAVRPLKRRPPKRTNELPPPNKLPGIFDNVHGSHGRQVCRRHELYVSFQDLGWLDWVIAPQGYSAYYCEGECSFPLDSCMNATNHAILQSLVHLLKPHAVPKACCAPTKVSATSVLYYDSSNNVILRKHRNMVVRACGCH", "length": 405, "header": "tr|G3MXA3-1|G3MXA3_BOVIN Isoform 1 of Bone morphotic protein 8a OS=Bos taurus OX=9913 GN=BMP8A PE=3 SV=3 CANONICAL=G3MXA3-1" }, "isoforms": [ { "isoform_ac": "G3MXA3-1", "url": "https://www.uniprot.org/uniprotkb/G3MXA3/entry", "sequence": { "sequence": "MAARPGPLWLLGLALCALSGGGIPGPRPPLGCPQRRLGPRERRDLQREILAVLGLPGRPRPRAPPAAALLPASAPLFMLDLYRAVADDDDEDGGAPERRLGRADLVMSFVNMVERDPALGHQEPHWKEFHFDLTQIPAGEAVTAAEFRIYKLPSTHPLNQTLHISMFEVVPEQSNRESDLFFLDLQTLRSGDEGWLVLDVTAASDRWLLSRNKDLGLRLYVETDDGRSVDPGLAGLLGRQAPRSKQPFVVTFFRASPGPGPARAPRAVRPLKRRPPKRTNELPPPNKLPGIFDNVHGSHGRQVCRRHELYVSFQDLGWLDWVIAPQGYSAYYCEGECSFPLDSCMNATNHAILQSLVHLLKPHAVPKACCAPTKVSATSVLYYDSSNNVILRKHRNMVVRACGCH", "length": 405, "header": "tr|G3MXA3-1|G3MXA3_BOVIN Isoform 1 of Bone morphotic protein 8a OS=Bos taurus OX=9913 GN=BMP8A PE=3 SV=3 CANONICAL=G3MXA3-1" }, "locus": { "chromosome": "3", "start_pos": 106584726, "end_pos": 106544063, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000065198.3", "url": "https://www.ensembl.org/id/ENSBTAT00000065198.3" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000054166.3", "url": "https://www.ensembl.org/id/ENSBTAP00000054166.3" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [ { "id": "bta:788948", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?bta:788948", "resource": "KEGG Pathway" } ], "orthologs": [ { "uniprot_canonical_ac": "A0ABK0LL73-1", "protein_name": "Succinyl-CoA:3-ketoacid-coenzyme A transferase", "gene_name": "Bmp8b", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": 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"MAARPGLLWLLGLALCVLGGGHLSHPPHVFPQRRLGVREPRDMQREIREVLGLPGRPRSRAPVGAAQQPASAPLFMLDLYRAMTDDSGGGTPQPHLDRADLIMSFVNIVERDRTLGYQEPHWKEFHFDLTQIPAGEAVTAAEFRIYKEPSTHPLNTTLHISMFEVVQEHSNRESDLFFLDLQTLRSGDEGWLVLDITAASDRWLLNHHKDLGLRLYVETEDGHSIDPGLAGLLGRQAPRSRQPFMVGFFRANQSPVRAPRTARPLKKKQLNQINQLPHSNKHLGILDDGHGSHGREVCRRHELYVSFRDLGWLDSVIAPQGYSAYYCAGECIYPLNSCMNSTNHATMQALVHLMKPDIIPKVCCVPTELSAISLLYYDRNNNVILRRERNMVVQACGCH", "length": 399 }, "evidence": [ { "id": "G3MXA3", "url": "https://omabrowser.org/oma/group/G3MXA3/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q7Z5Y6-1", "protein_name": "Bone morphogenetic protein 8A", "gene_name": "BMP8A", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MAARPGPLWLLGLTLCALGGGGPGLRPPPGCPQRRLGARERRDVQREILAVLGLPGRPRPRAPPAASRLPASAPLFMLDLYHAMAGDDDEDGAPAEQRLGRADLVMSFVNMVERDRALGHQEPHWKEFRFDLTQIPAGEAVTAAEFRIYKVPSIHLLNRTLHVSMFQVVQEQSNRESDLFFLDLQTLRAGDEGWLVLDVTAASDCWLLKRHKDLGLRLYVETEDGHSVDPGLAGLLGQRAPRSQQPFVVTFFRASPSPIRTPRAVRPLRRRQPKKSNELPQANRLPGIFDDVRGSHGRQVCRRHELYVSFQDLGWLDWVIAPQGYSAYYCEGECSFPLDSCMNATNHAILQSLVHLMKPNAVPKACCAPTKLSATSVLYYDSSNNVILRKHRNMVVKACGCH", "length": 402 }, "evidence": [ { "id": "G3MXA3", "url": "https://omabrowser.org/oma/group/G3MXA3/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" } ], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 1, "go_terms": [ { "name": "extracellular space", "id": "GO:0005615", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005615", "evidence": [ { "database": "UniProtKB", "id": "G3MXA3", "url": "https://www.uniprot.org/uniprotkb/G3MXA3" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 4, "go_terms": [ { "name": "cell differentiation", "id": "GO:0030154", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030154", "evidence": [ { "database": "UniProtKB", "id": "G3MXA3", "url": "https://www.uniprot.org/uniprotkb/G3MXA3" } ], "pmid": "" }, { "name": "BMP signaling pathway", "id": "GO:0030509", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030509", "evidence": [ { "database": "UniProtKB", "id": "G3MXA3", "url": "https://www.uniprot.org/uniprotkb/G3MXA3" } ], "pmid": "" }, { "name": "ossification", "id": "GO:0001503", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0001503", "evidence": [ { "database": "UniProtKB", "id": "G3MXA3", "url": "https://www.uniprot.org/uniprotkb/G3MXA3" } ], "pmid": "" }, { "name": "cartilage development", "id": "GO:0051216", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0051216", "evidence": [ { "database": "UniProtKB", "id": "G3MXA3", "url": "https://www.uniprot.org/uniprotkb/G3MXA3" } ], "pmid": "" } ] }, { "name": "Molecular Function", "total": 2, "go_terms": [ { "name": "cytokine activity", "id": "GO:0005125", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005125", "evidence": [ { "database": "UniProtKB", "id": "G3MXA3", "url": "https://www.uniprot.org/uniprotkb/G3MXA3" } ], "pmid": "" }, { "name": "growth factor activity", "id": "GO:0008083", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008083", "evidence": [ { "database": "UniProtKB", "id": "G3MXA3", "url": "https://www.uniprot.org/uniprotkb/G3MXA3" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 159, "end_pos": 161, "annotation": "n_glycosylation_sequon" }, { "start_pos": 346, "end_pos": 348, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [ { "pdb_id": "AF-G3MXA3-F1", "pdb_chain": "global", "start_pos": 1, "end_pos": 405, "overlap": "1.0", "method": "AlphaFold", "type": "alphafold", "resolution": -1.0, "url": "https://data.glygen.org/ln2downloads/pdb/current/AF-G3MXA3-F1.pdb", "url_external": "https://alphafold.ebi.ac.uk/entry/G3MXA3" } ], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "G3MXA3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3MXA3" }, { "id": "PS51362", "database": "PROSITE", "url": "https://prosite.expasy.org/PS51362" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "TGF-beta family profile", "eco_id": "ECO_0000259", "start_pos": 275, "end_pos": 405, "start_aa": "Pro", "end_aa": "His", "glycosite_overlap": [] } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "homologset.oma", "label": "OMA Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 159, "end_pos": 161 }, { "start_pos": 346, "end_pos": 348 } ] }, "class_list": [], 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"Bovine", "reference_species": "Bos taurus [9913]" } ], "gene": [ { "name": "FAM43B", "url": "https://www.uniprot.org/uniprotkb/G3MXB0", "locus": { "chromosome": "2", "start_pos": 132076687, "end_pos": 132077658, "strand": "+", "evidence": [ { "database": "Ensembl Gene", "id": "ENSBTAG00000046988", "url": "https://www.ensembl.org/id/ENSBTAG00000046988" } ] } } ], "crossref": [ { "id": "G3MXB0", "url": "https://alphafold.ebi.ac.uk/entry/G3MXB0", "database": "AlphaFoldDB", "categories": [] }, { "id": "ENSBTAG00000046988", "url": "https://bgee.org/?page=gene&gene_id=ENSBTAG00000046988", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "IPR006020", "url": "https://www.ebi.ac.uk/interpro/entry/IPR006020", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR011993", "url": "https://www.ebi.ac.uk/interpro/entry/IPR011993", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR051133", "url": "https://www.ebi.ac.uk/interpro/entry/IPR051133", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "bta:100298683", "url": "https://www.genome.jp/dbget-bin/www_bget?bta:100298683", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "TPCEKGA", "url": "https://omabrowser.org/oma/group/TPCEKGA/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "G3MXB0", "url": "https://www.orthodb.org/?gene=G3MXB0", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR11232", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR11232", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR11232:SF34", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR11232:SF34", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF14719", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF14719", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "G3MXB0", "url": "https://www.uniprot.org/uniprotkb/G3MXB0", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "G3MXB0-1", "url": "https://www.uniprot.org/uniprotkb/G3MXB0-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MLPWRRNKFVLVEDDAKRKAKSLSPGLAYTSLLSSFLRSCPDLLPDWPLERLGRVFRSRRQKVELNKEDPTYTVWYLGNAVTLHAKGDGCTDDAVGKIWARCGPGGGTKMKLTLGPHGLRMQPCERSSSGGPGGRRPAHAYLLPRITYCAADARHPRVFTWVYRHQARHKAVVLRCHAVLLARAHKARALARLLRQTALAAFTDFKRLQRQSDARHVRQQHLRAGGAPAASLPRAPLRRLLNAKCAYRPPPAAERGRGAPRLSSIQEEDEDQDEDTLPENQEGGLGSWPPGETVGLPVARLAFLERPALGRHSYSGKNSGPGELRPGPRWHLSTANPHKEECPASVPGLATPWRTSGTSLLCLWRKRGCSYHPQLQTAQEQLFASGRCPSLCPGTHRTPHPPCLSAYKCVWVPARCPTARTKTWPPREVRGHLAGV", "length": 436, "header": "tr|G3MXB0-1|G3MXB0_BOVIN Isoform 1 of Family with sequence similarity 43 member B OS=Bos taurus OX=9913 GN=FAM43B PE=4 SV=2 CANONICAL=G3MXB0-1" }, "isoforms": [ { "isoform_ac": "G3MXB0-1", "url": "https://www.uniprot.org/uniprotkb/G3MXB0/entry", "sequence": { "sequence": "MLPWRRNKFVLVEDDAKRKAKSLSPGLAYTSLLSSFLRSCPDLLPDWPLERLGRVFRSRRQKVELNKEDPTYTVWYLGNAVTLHAKGDGCTDDAVGKIWARCGPGGGTKMKLTLGPHGLRMQPCERSSSGGPGGRRPAHAYLLPRITYCAADARHPRVFTWVYRHQARHKAVVLRCHAVLLARAHKARALARLLRQTALAAFTDFKRLQRQSDARHVRQQHLRAGGAPAASLPRAPLRRLLNAKCAYRPPPAAERGRGAPRLSSIQEEDEDQDEDTLPENQEGGLGSWPPGETVGLPVARLAFLERPALGRHSYSGKNSGPGELRPGPRWHLSTANPHKEECPASVPGLATPWRTSGTSLLCLWRKRGCSYHPQLQTAQEQLFASGRCPSLCPGTHRTPHPPCLSAYKCVWVPARCPTARTKTWPPREVRGHLAGV", "length": 436, "header": "tr|G3MXB0-1|G3MXB0_BOVIN Isoform 1 of Family with sequence similarity 43 member B OS=Bos taurus OX=9913 GN=FAM43B PE=4 SV=2 CANONICAL=G3MXB0-1" }, "locus": { "chromosome": "2", "start_pos": 132077658, "end_pos": 132075818, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000063072.3", "url": "https://www.ensembl.org/id/ENSBTAT00000063072.3" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000054174.2", "url": "https://www.ensembl.org/id/ENSBTAP00000054174.2" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [ { "id": "bta:100298683", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?bta:100298683", "resource": "KEGG Pathway" } ], "orthologs": [ { "uniprot_canonical_ac": "A0A8V0ZKZ4-1", "protein_name": "Family with sequence similarity 43 member B", "gene_name": "FAM43B", "tax_id": 9031, "organism": "Gallus gallus", "sequence": { "sequence": "MLPWRRSKFVLVENERKCKGKSLGPGLGYASLLAGFLRSCPDLLPECPLERLGAVFGGRRQKVELNKEDPTYTVRYLGNAVTLHAKGEGCTEEAVGKIWAKSDAGAGGAKMKLTLGPHGIRMAPGEKGARRSGHAYLLHRITYCTADRRHPKVFAWVYRHQVKNKAVVLRCHAVLVPKAATARAMALLLFQTSASAFDEFKRLKRQNDGRRLQQQLLGEAIVPLVPLRRLLNAKCPYRPPAERARCAPRLSSILEEDEEETGGTWGDGGPTVVSLASEMRGCSLRGPRAPIC", "length": 292 }, "evidence": [ { "id": "G3MXB0", "url": "https://omabrowser.org/oma/group/G3MXB0/", "database": "OMA" } ], "glygen_name": "Chicken", "common_name": "Chicken" }, { "uniprot_canonical_ac": "A2AM80-1", "protein_name": "Family with sequence similarity 43, member B", "gene_name": "Fam43b", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MLPWRRNKFVLVEDEAKRKAKSLSPGLAYTSLLSSFLRSCPDLLPDWPLERLGRVFRSRRQKVELNKEDPTYTVWYLGNAVTLHAKGDGCTDDAVGRIWARCGPGGGTKMKLTLGPHGIRMQPSERSSGASGGRRPAHAYLLPRITYCAADGRHPRVFTWVYRHQARHKAVVLRCHAVLLARAHKARSLARLLHQTALAAFSDFKRLQRQSDARHVRQQHLRAGGAAASVPRAPLRRLLNAKCAYRPPPGERGRGAPRLSSIQEEDEEEDAEEEDTRDSEEGALQRERPEVLSLARELRTCSLRGAPAPPPPAQPRRWKAGSRERAGQAR", "length": 330 }, "evidence": [ { "id": "G3MXB0", "url": "https://omabrowser.org/oma/group/G3MXB0/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q6ZT52-1", "protein_name": "Protein FAM43B", "gene_name": "FAM43B", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MLPWRRNKFVLVEDEAKCKAKSLSPGLAYTSLLSSFLRSCPDLLPDWPLERLGRVFRSRRQKVELNKEDPTYTVWYLGNAVTLHAKGDGCTDDAVGKIWARCGPGGGTKMKLTLGPHGIRMQPCERSAAGGSGGRRPAHAYLLPRITYCTADGRHPRVFAWVYRHQARHKAVVLRCHAVLLARAHKARALARLLRQTALAAFSDFKRLQRQSDARHVRQQHLRAGGAAASVPRAPLRRLLNAKCAYRPPPSERSRGAPRLSSIQEEDEEEEEDDAEEQEGGVPQRERPEVLSLARELRTCSLRGAPAPPPPAQPRRWKAGPRERAGQAR", "length": 329 }, "evidence": [ { "id": "G3MXB0", "url": "https://omabrowser.org/oma/group/G3MXB0/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" } ], "go_annotation": {}, "pro_annotation": [], "site_annotation": [], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [ { "pdb_id": "AF-G3MXB0-F1", "pdb_chain": "global", "start_pos": 1, "end_pos": 436, "overlap": "1.0", "method": "AlphaFold", "type": "alphafold", "resolution": -1.0, "url": "https://data.glygen.org/ln2downloads/pdb/current/AF-G3MXB0-F1.pdb", "url_external": "https://alphafold.ebi.ac.uk/entry/G3MXB0" } ], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "G3MXB0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3MXB0" }, { "id": "SM00462", "database": "SMART", "url": "http://smart.embl.de/smart/do_annotation.pl?DOMAIN=SM00462" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "PID", "eco_id": "ECO_0000259", "start_pos": 67, "end_pos": 211, "start_aa": "Lys", "end_aa": "Gln", "glycosite_overlap": [] } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "homologset.oma", "label": "OMA Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ], "tool_support": { "graph_view": "yes" } }, { "uniprot_canonical_ac": "G3MXB5-1", "uniprot_ac": "G3MXB5", "uniprot_id": "G3MXB5_BOVIN", "mass": { "chemical_mass": 47160.0, "monoisotopic_mass": 47160.0 }, "refseq": {}, "gene_names": [ { "name": "LOC524810", "type": "recommended", "evidence": [ { "id": "G3MXB5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3MXB5" } ] } ], "protein_names": [ { "name": "Ig-like domain-containing protein", "type": "recommended", "evidence": [ { "id": "G3MXB5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3MXB5/entry#names_and_taxonomy" } ] } ], "function": [], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Bos taurus", "taxid": 9913, "evidence": [ { "database": "UniProtKB", "id": "G3MXB5", "url": "https://www.uniprot.org/uniprotkb/G3MXB5" } ], "common_name": "Bovine", "glygen_name": "Bovine", "reference_species": "Bos taurus [9913]" } ], "gene": [ { "name": "LOC524810", "url": "https://www.uniprot.org/uniprotkb/G3MXB5", "locus": {} } ], "crossref": [ { "id": "G3MXB5", "url": "https://alphafold.ebi.ac.uk/entry/G3MXB5", "database": "AlphaFoldDB", "categories": [] }, { "id": "ENSBTAG00000047700", "url": "https://bgee.org/?page=gene&gene_id=ENSBTAG00000047700", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "cd04986", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd04986", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "cd05768", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd05768", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "IPR003006", "url": "https://www.ebi.ac.uk/interpro/entry/IPR003006", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR003597", "url": "https://www.ebi.ac.uk/interpro/entry/IPR003597", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR007110", "url": "https://www.ebi.ac.uk/interpro/entry/IPR007110", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR013151", "url": "https://www.ebi.ac.uk/interpro/entry/IPR013151", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR013783", "url": "https://www.ebi.ac.uk/interpro/entry/IPR013783", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR036179", "url": "https://www.ebi.ac.uk/interpro/entry/IPR036179", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR050380", "url": "https://www.ebi.ac.uk/interpro/entry/IPR050380", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "PTHR23411", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR23411", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00047", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00047", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF07654", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF07654", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "A0ABI0NN10", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NN10", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0ABI0NN10-1", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NN10-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0ABI0P498", "url": "https://www.uniprot.org/uniprotkb/A0ABI0P498", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0ABI0P498-1", "url": "https://www.uniprot.org/uniprotkb/A0ABI0P498-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "G3MXB5", "url": "https://www.uniprot.org/uniprotkb/G3MXB5", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "G3MXB5-1", "url": "https://www.uniprot.org/uniprotkb/G3MXB5-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MATQNFERNLLLNLYRKGKNLTLVVCFLLPLEREKKCLTLAAYFLWRLLALLPVPPSVATLGQSLTLCVKERGAPPCVRGAVRGPVSRGLLSHSAPCVSESETSPSIFPLSLGNNDPAGQVVIGCLVQGFFPSAPLSVTWNQNGDSVSVRNFPAVLAGSLYTMSSQLTLPASLCPKGQSVTCQVQHLSKASKTVAVPCIIQDSSSCCVPNCEPSLSVQPPALEDLLLGSNASLTCTLSGLKSAEGASFTWNPTGGKTAVQGSPKRDSCGCYSVSSVLPGCADPWNSGQTFSCSVTHPESKSSLTATIKKDLGNTFRPQVHLLPPPSEELALNELVTLTCLVRGFSPKEVLVRWLQGNQELPREKYLTWGPLPEAGQSVTTFAVTSVLRVDAEVWKQGDTFSCMVGHEALPLAFTQKTIDRLAGKPTHVNVSVVMSEVDGVCY", "length": 442, "header": "tr|G3MXB5-1|G3MXB5_BOVIN Isoform 1 of Ig-like domain-containing protein OS=Bos taurus OX=9913 GN=LOC524810 PE=1 SV=4 CANONICAL=G3MXB5-1" }, "isoforms": [ { "isoform_ac": "A0ABI0NN10-1", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NN10/entry", "sequence": { "sequence": "MAHLDSESETSPSIFPLSLGNNDPAGQVVIGCLVQGFFPSAPLSVTWNQNGDSVSVRNFPAVLAGSLYTMSSQLTLPASLCPKGQSVTCQVQHLSKASKTVAVPCIIQDSSSCCVPNCEPSLSVQPPALEDLLLGSNASLTCTLSGLKSAEGASFTWNPTGGKTAVQGSPKRDSCGCYSVSSVLPGCADPWNSGQTFSCSVTHPESKSSLTATIKKDLGNTFRPQVHLLPPPSEELALNELVTLTCLVRGFSPKEVLVRWLQGNQELPREKYLTWGPLPEAGQSVTTFAVTSVLRVDAEVWKQGDTFSCMVGHEALPLAFTQKTIDRLAEHQPWLVLDLMQSSPEEDSPEASLWPTTVTLLTLFLLSLFYSTALTVTSIRTTPDSREVPQY", "length": 391, "header": "tr|A0ABI0NN10-1|A0ABI0NN10_BOVIN Computationally mapped isoform of Ig-like domain-containing protein OS=Bos taurus OX=9913 GN=LOC524810 PE=1 SV=1 CANONICAL=G3MXB5-1" }, "locus": { "chromosome": "20", "start_pos": 71968318, "end_pos": 71964249, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000138293.1", "url": "https://www.ensembl.org/id/ENSBTAT00000138293.1" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000106963.1", "url": "https://www.ensembl.org/id/ENSBTAP00000106963.1" } ] } }, { "isoform_ac": "A0ABI0P498-1", "url": "https://www.uniprot.org/uniprotkb/A0ABI0P498/entry", "sequence": { "sequence": "SESETSPSIFPLSLGNNDPAGQVVIGCLVQGFFPSAPLSVTWNQNGDSVSVRNFPAVLAGSLYTMSSQLTLPASLCPKGQSVTCQVQHLSKASKTVAVPCIIQDSSSCCVPNCEPSLSVQPPALEDLLLGSNASLTCTLSGLKSAEGASFTWNPTGGKTAVQGSPKRDSCGCYSVSSVLPGCADPWNSGQTFSCSVTHPESKSSLTATIKKDLGNTFRPQVHLLPPPSEELALNELVTLTCLVRGFSPKEVLVRWLQGNQELPREKYLTWGPLPEAGQSVTTFAVTSVLRVDAEVWKQGDTFSCMVGHEALPLAFTQKTIDRLAGKPTHVNVSVVMSEVDGVCY", "length": 344, "header": "tr|A0ABI0P498-1|A0ABI0P498_BOVIN Computationally mapped isoform of Ig-like domain-containing protein OS=Bos taurus OX=9913 GN=LOC524810 PE=1 SV=1 CANONICAL=G3MXB5-1" }, "locus": { "chromosome": "20", "start_pos": 71965827, "end_pos": 71964428, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000147468.1", "url": "https://www.ensembl.org/id/ENSBTAT00000147468.1" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000105676.1", "url": "https://www.ensembl.org/id/ENSBTAP00000105676.1" } ] } }, { "isoform_ac": "G3MXB5-1", "url": "https://www.uniprot.org/uniprotkb/G3MXB5/entry", "sequence": { "sequence": "MATQNFERNLLLNLYRKGKNLTLVVCFLLPLEREKKCLTLAAYFLWRLLALLPVPPSVATLGQSLTLCVKERGAPPCVRGAVRGPVSRGLLSHSAPCVSESETSPSIFPLSLGNNDPAGQVVIGCLVQGFFPSAPLSVTWNQNGDSVSVRNFPAVLAGSLYTMSSQLTLPASLCPKGQSVTCQVQHLSKASKTVAVPCIIQDSSSCCVPNCEPSLSVQPPALEDLLLGSNASLTCTLSGLKSAEGASFTWNPTGGKTAVQGSPKRDSCGCYSVSSVLPGCADPWNSGQTFSCSVTHPESKSSLTATIKKDLGNTFRPQVHLLPPPSEELALNELVTLTCLVRGFSPKEVLVRWLQGNQELPREKYLTWGPLPEAGQSVTTFAVTSVLRVDAEVWKQGDTFSCMVGHEALPLAFTQKTIDRLAGKPTHVNVSVVMSEVDGVCY", "length": 442, "header": "tr|G3MXB5-1|G3MXB5_BOVIN Isoform 1 of Ig-like domain-containing protein OS=Bos taurus OX=9913 GN=LOC524810 PE=1 SV=4 CANONICAL=G3MXB5-1" }, "locus": { "chromosome": "20", "start_pos": 71965827, "end_pos": 71963200, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000063930.4", "url": "https://www.ensembl.org/id/ENSBTAT00000063930.4" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000054179.4", "url": "https://www.ensembl.org/id/ENSBTAP00000054179.4" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [], "orthologs": [], "go_annotation": {}, "pro_annotation": [], "site_annotation": [ { "start_pos": 20, "end_pos": 22, "annotation": "n_glycosylation_sequon" }, { "start_pos": 230, "end_pos": 232, "annotation": "n_glycosylation_sequon" }, { "start_pos": 429, "end_pos": 431, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [ { "pdb_id": "AF-G3MXB5-F1", "pdb_chain": "global", "start_pos": 1, "end_pos": 442, "overlap": "1.0", "method": "AlphaFold", "type": "alphafold", "resolution": -1.0, "url": "https://data.glygen.org/ln2downloads/pdb/current/AF-G3MXB5-F1.pdb", "url_external": "https://alphafold.ebi.ac.uk/entry/G3MXB5" } ], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "G3MXB5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3MXB5" }, { "id": "PS50835", "database": "PROSITE", "url": "https://prosite.expasy.org/PS50835" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "Ig-like", "eco_id": "ECO_0000259", "start_pos": 105, "end_pos": 195, "start_aa": "Pro", "end_aa": "Ala", "glycosite_overlap": [] } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 20, "end_pos": 22 }, { "start_pos": 230, "end_pos": 232 }, { "start_pos": 429, "end_pos": 431 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": 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"count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ], "tool_support": { "graph_view": "yes" } }, { "uniprot_canonical_ac": "G3MXB8-1", "uniprot_ac": "G3MXB8", "uniprot_id": "G3MXB8_BOVIN", "mass": { "chemical_mass": 13453.0, "monoisotopic_mass": 13453.0 }, "refseq": { "ac": "NP_001192450", "name": "proline-rich protein 15", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001192450" }, "gene_names": [ { "name": "PRR15", "type": "recommended", "evidence": [ { "id": "G3MXB8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3MXB8" } ] }, { "name": "P-AF", "type": "synonym", "evidence": [ { "id": "NP_001192450", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001192450" } ] }, { "name": "PRR15", "type": "synonym", "evidence": [ { "id": "NP_001192450", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001192450" } ] } ], "protein_names": [ { "name": "Proline rich 15", "type": "synonym", "evidence": [ { "id": "G3MXB8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3MXB8/entry#names_and_taxonomy" } ] }, { "name": "proline-rich protein 15", "type": "synonym", "evidence": [ { "id": "NP_001192450", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001192450" } ] } ], "function": [], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Bos taurus", "taxid": 9913, "evidence": [ { "database": "UniProtKB", "id": "G3MXB8", "url": "https://www.uniprot.org/uniprotkb/G3MXB8" } ], "common_name": "Bovine", "glygen_name": "Bovine", "reference_species": "Bos taurus [9913]" } ], "gene": [ { "name": "PRR15", "url": "https://www.uniprot.org/uniprotkb/G3MXB8", "locus": { "chromosome": "4", "start_pos": 66608643, "end_pos": 66613682, "strand": "+", "evidence": [ { "database": "Ensembl Gene", "id": "ENSBTAG00000045567", "url": "https://www.ensembl.org/id/ENSBTAG00000045567" } ] } } ], "crossref": [ { "id": "ENSBTAG00000045567", "url": "https://bgee.org/?page=gene&gene_id=ENSBTAG00000045567", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "538952", "url": "https://www.ncbi.nlm.nih.gov/gene/538952", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR028237", "url": "https://www.ebi.ac.uk/interpro/entry/IPR028237", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "bta:538952", "url": "https://www.genome.jp/dbget-bin/www_bget?bta:538952", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "GAWWKSL", "url": "https://omabrowser.org/oma/group/GAWWKSL/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "G3MXB8", "url": "https://www.orthodb.org/?gene=G3MXB8", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR14581", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR14581", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR14581:SF4", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR14581:SF4", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF15321", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF15321", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "NP_001192450", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001192450", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "G3MXB8", "url": "https://www.uniprot.org/uniprotkb/G3MXB8", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "G3MXB8-1", "url": "https://www.uniprot.org/uniprotkb/G3MXB8-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MADGSGTGSSGSWWNSLTNSRKKNKEATGGAQPPAQPAPGEPAPPVQDWTSSSRENQHPSLLGGAGEPHKLDKLGGEKSGNSRRNLKISRSGRFKEKRKVRATLLPEGVRSSEEAIFPGDPHDDKQ", "length": 126, "header": "tr|G3MXB8-1|G3MXB8_BOVIN Isoform 1 of Proline rich 15 OS=Bos taurus OX=9913 GN=PRR15 PE=3 SV=1 CANONICAL=G3MXB8-1" }, "isoforms": [ { "isoform_ac": "G3MXB8-1", "url": "https://www.uniprot.org/uniprotkb/G3MXB8/entry", "sequence": { "sequence": "MADGSGTGSSGSWWNSLTNSRKKNKEATGGAQPPAQPAPGEPAPPVQDWTSSSRENQHPSLLGGAGEPHKLDKLGGEKSGNSRRNLKISRSGRFKEKRKVRATLLPEGVRSSEEAIFPGDPHDDKQ", "length": 126, "header": "tr|G3MXB8-1|G3MXB8_BOVIN Isoform 1 of Proline rich 15 OS=Bos taurus OX=9913 GN=PRR15 PE=3 SV=1 CANONICAL=G3MXB8-1" }, "locus": { "chromosome": "4", "start_pos": 66609848, "end_pos": 66609471, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000065419.3", "url": "https://www.ensembl.org/id/ENSBTAT00000065419.3" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000054182.1", "url": "https://www.ensembl.org/id/ENSBTAP00000054182.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [ { "id": "bta:538952", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?bta:538952", "resource": "KEGG Pathway" } ], "orthologs": [ { "uniprot_canonical_ac": "A0A8V0X6U0-1", "protein_name": "Proline rich 15", 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griseus", "sequence": { "sequence": "MADSGSPTSSSGPWWKSLTRKKSKEVTVGAQPCVQPEAEDQTPPYSDRTSSSRENQHSDVLGDTGETPRSEKLCEEKSCNSRRNLKISRSGRFKEKRKVRATLLPEGDRSPEEADFPDDPQEDKQ", "length": 125 }, "evidence": [ { "id": "G3MXB8", "url": "https://omabrowser.org/oma/group/G3MXB8/", "database": "OMA" } ], "glygen_name": "Hamster", "common_name": "Chinese hamster" }, { "uniprot_canonical_ac": "Q8IV56-1", "protein_name": "Proline-rich protein 15", "gene_name": "PRR15", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MADSGDAGSSGPWWKSLTNSRKKSKEAAVGVPPPAQPAPGEPTPPAPPSPDWTSSSRENQHPNLLGGAGEPPKPDKLYGDKSGSSRRNLKISRSGRFKEKRKVRATLLPEAGRSPEEAGFPGDPHEDKQ", "length": 129 }, "evidence": [ { "id": "G3MXB8", "url": "https://omabrowser.org/oma/group/G3MXB8/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" } ], "go_annotation": {}, "pro_annotation": [], "site_annotation": [], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], 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taurus [9913]" } ], "gene": [ { "name": "C28H10orf71", "url": "https://www.uniprot.org/uniprotkb/G3MXB9", "locus": { "chromosome": "28", "start_pos": 43551966, "end_pos": 43547659, "strand": "-", "evidence": [ { "database": "Ensembl Gene", "id": "ENSBTAG00000047155", "url": "https://www.ensembl.org/id/ENSBTAG00000047155" } ] } } ], "crossref": [ { "id": "ENSBTAG00000047155", "url": "https://bgee.org/?page=gene&gene_id=ENSBTAG00000047155", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "540418", "url": "https://www.ncbi.nlm.nih.gov/gene/540418", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR027838", "url": "https://www.ebi.ac.uk/interpro/entry/IPR027838", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR052303", "url": "https://www.ebi.ac.uk/interpro/entry/IPR052303", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "G3MXB9", "url": "https://www.orthodb.org/?gene=G3MXB9", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR33775", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR33775", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR33775:SF2", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR33775:SF2", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF15232", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF15232", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "XP_002699014", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_002699014", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "G3MXB9", "url": "https://www.uniprot.org/uniprotkb/G3MXB9", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "G3MXB9-1", "url": "https://www.uniprot.org/uniprotkb/G3MXB9-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MQGSKKCMDGFSDSSSIGSVLDDADKEVSSLTDRAFRSLCISEDASFHDSDLALSPDITRQVFGNFHQGTVSHTHRKSGIWSQLPSQGTEHAGWAATFQQLPKYVQGEEKYPKSSSPLTPAQRRLEVPVSGLRSSNKPISKVSSLIKSFDRTESQRCDSGPPTSKPPALKNPPKFAPLPESGVNFCFDSAFLTVRRVPAEVSSTHQASHQPGRKHGEQEAPKNPEMASHGPNSFLPTSEHAANSFEPKFPSPAHKAATSEPGRGQEWARKGTFLHSENSAFESWNAHQPRLPERKDAADAVPESKALKRYEDTPLLREPPASEQKTSPCHVRANCSQEENKMAAGTLSTSGTWVSRDLGAQIFAMEEKASSSQADPPPLKPTHAPWRKPKPGKGGKDNLQDASEEKKQTNWRGPALYTKHNPQVQFPEKDALDMPVEPHEHYDPPFNISKLLTPVIPTKQVLESSDSQPAEITPTPPGQLNGYQEKDPSDCQSRDSYKSKAPSLLFNLKDVRKRVKSTYSPSPLMKGPDEKTRGNQESLSNGGLLPNGLEENPPDEFSKETPDDSPSVPLTSTQKDPKADPDAASADTYLTPTSPSIITKAPFCVNGEAANRNNYEKDDTNGESEMHDARPSWRSDSRQRLHRKHLSLKLCSEDPEAGKAAETQKTSGLENGFLRSISQETEPERQAGLQNPNFNPKFSPGPLSPEEEDVFYSDSQSDFMPGLKSKAKFSTSSSDQSFASFEDQQKTWFAETQQEDGRNNMNAGDGWKDEQEKVMEEDELEYGAVSNGNACVEEHSKRESLPEEESLPGGSPRKAPREEADFRRTGTGGSKSDTALPHAGGLAPSPGSTSNKHILFTIKDNTLRATPVIKPIMLPLLRSVSSESPLGSGHKEEELPRPGWGGDAGLCAPESQEMPSTLTPTSARGTHVKGVACEGLEGQERVPSATRPEASQAAPKWHVPSSPLTGEGQGLKPPQKATQKVTVNNCKSGSTDPVKLDAPRCIPTITLPEDDPEDQLPPQQLGAFWEEQVQGFNSHFLSTPRAGPPGRRWVTGELAASPNASSLEENSACSPAASSIWDDASQALSEPGLLPGEPPRSSPWASPSPGRVARREDLTHALAWEPGSDPQLEPSAEDLRTLSPRGSLLDVATSSASLLEKPEPPAQLERAAGKPPAVPPKTEKALRRAKKLASKRRKIDQPQEKHGERREEKLNPEDSERRPLSPGERPRPRLPVVRALPPPAHRHSVSALSEPVQRRPGGPQSLTPQPPYPATQKVLQDPQSGEYFVFDLPLQVKIKTFYDPETGKYVKVSIPSSEGASPEPTPLDALAAPYVLYPGFRPLPVTALMPLRCSSQLSAPTFLRQRPHTAEAAGLRPQSVHEVGLQLPSAAPSNPTQPSAGQRPEGHPQSAGQEGGDAPSLGIIPTNDLEDFATEGIS", "length": 1434, "header": "tr|G3MXB9-1|G3MXB9_BOVIN Isoform 1 of Chromosome 28 C10orf71 homolog OS=Bos taurus OX=9913 GN=C28H10orf71 PE=4 SV=4 CANONICAL=G3MXB9-1" }, "isoforms": [ { "isoform_ac": "G3MXB9-1", "url": "https://www.uniprot.org/uniprotkb/G3MXB9/entry", "sequence": { "sequence": "MQGSKKCMDGFSDSSSIGSVLDDADKEVSSLTDRAFRSLCISEDASFHDSDLALSPDITRQVFGNFHQGTVSHTHRKSGIWSQLPSQGTEHAGWAATFQQLPKYVQGEEKYPKSSSPLTPAQRRLEVPVSGLRSSNKPISKVSSLIKSFDRTESQRCDSGPPTSKPPALKNPPKFAPLPESGVNFCFDSAFLTVRRVPAEVSSTHQASHQPGRKHGEQEAPKNPEMASHGPNSFLPTSEHAANSFEPKFPSPAHKAATSEPGRGQEWARKGTFLHSENSAFESWNAHQPRLPERKDAADAVPESKALKRYEDTPLLREPPASEQKTSPCHVRANCSQEENKMAAGTLSTSGTWVSRDLGAQIFAMEEKASSSQADPPPLKPTHAPWRKPKPGKGGKDNLQDASEEKKQTNWRGPALYTKHNPQVQFPEKDALDMPVEPHEHYDPPFNISKLLTPVIPTKQVLESSDSQPAEITPTPPGQLNGYQEKDPSDCQSRDSYKSKAPSLLFNLKDVRKRVKSTYSPSPLMKGPDEKTRGNQESLSNGGLLPNGLEENPPDEFSKETPDDSPSVPLTSTQKDPKADPDAASADTYLTPTSPSIITKAPFCVNGEAANRNNYEKDDTNGESEMHDARPSWRSDSRQRLHRKHLSLKLCSEDPEAGKAAETQKTSGLENGFLRSISQETEPERQAGLQNPNFNPKFSPGPLSPEEEDVFYSDSQSDFMPGLKSKAKFSTSSSDQSFASFEDQQKTWFAETQQEDGRNNMNAGDGWKDEQEKVMEEDELEYGAVSNGNACVEEHSKRESLPEEESLPGGSPRKAPREEADFRRTGTGGSKSDTALPHAGGLAPSPGSTSNKHILFTIKDNTLRATPVIKPIMLPLLRSVSSESPLGSGHKEEELPRPGWGGDAGLCAPESQEMPSTLTPTSARGTHVKGVACEGLEGQERVPSATRPEASQAAPKWHVPSSPLTGEGQGLKPPQKATQKVTVNNCKSGSTDPVKLDAPRCIPTITLPEDDPEDQLPPQQLGAFWEEQVQGFNSHFLSTPRAGPPGRRWVTGELAASPNASSLEENSACSPAASSIWDDASQALSEPGLLPGEPPRSSPWASPSPGRVARREDLTHALAWEPGSDPQLEPSAEDLRTLSPRGSLLDVATSSASLLEKPEPPAQLERAAGKPPAVPPKTEKALRRAKKLASKRRKIDQPQEKHGERREEKLNPEDSERRPLSPGERPRPRLPVVRALPPPAHRHSVSALSEPVQRRPGGPQSLTPQPPYPATQKVLQDPQSGEYFVFDLPLQVKIKTFYDPETGKYVKVSIPSSEGASPEPTPLDALAAPYVLYPGFRPLPVTALMPLRCSSQLSAPTFLRQRPHTAEAAGLRPQSVHEVGLQLPSAAPSNPTQPSAGQRPEGHPQSAGQEGGDAPSLGIIPTNDLEDFATEGIS", "length": 1434, "header": "tr|G3MXB9-1|G3MXB9_BOVIN Isoform 1 of Chromosome 28 C10orf71 homolog OS=Bos taurus OX=9913 GN=C28H10orf71 PE=4 SV=4 CANONICAL=G3MXB9-1" }, "locus": { "chromosome": "28", "start_pos": 43551963, "end_pos": 43547662, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000148030.1", "url": "https://www.ensembl.org/id/ENSBTAT00000148030.1" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000106953.1", "url": "https://www.ensembl.org/id/ENSBTAP00000106953.1" } ] } } ], "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "other", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 475, "start_aa": "Thr", "end_pos": 475, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr475", "evidence": [ { "id": "", "database": "GlyGen", "url": "https://data.glygen.org/" } ], "filter_code": "000000000000000010000.00000000001000.0.01000" } ], "phosphorylation": [], "glycation": [], "keywords": [ "glycoprotein", "glycoprotein_predicted" ], "publication": [], "pathway": [], "orthologs": [], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 1, "go_terms": [ { "name": "Z disc", "id": "GO:0030018", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030018", "evidence": [ { "database": "UniProtKB", "id": "G3MXB9", "url": "https://www.uniprot.org/uniprotkb/G3MXB9" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 1, "go_terms": [ { "name": "positive regulation of calcineurin-NFAT signaling cascade", "id": "GO:0070886", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0070886", "evidence": [ { "database": "UniProtKB", "id": "G3MXB9", "url": "https://www.uniprot.org/uniprotkb/G3MXB9" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 1059, "end_pos": 1061, "annotation": "n_glycosylation_sequon" }, { "start_pos": 334, "end_pos": 336, "annotation": "n_glycosylation_sequon" }, { "start_pos": 447, "end_pos": 449, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "G3MXB9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3MXB9" }, { "id": "PF15232", "database": "Pfam", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF15232" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "DUF4585", "eco_id": "ECO_0000259", "start_pos": 1267, "end_pos": 1338, "start_aa": "Pro", "end_aa": "Pro", "glycosite_overlap": [] } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [ 475 ], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 1059, "end_pos": 1061 }, { "start_pos": 334, "end_pos": 336 }, { "start_pos": 447, "end_pos": 449 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 1 }, { "field": "total_sites", "count": 1 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 1 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "exact_sites", "count": 1 }, { "field": "exact_o_linked_sites", "count": 1 }, { "field": "fuzzy_sites", "count": 0 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_pos", "start_aa", "end_pos", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_reported", "table_stats": [ 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"o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ], "tool_support": { "graph_view": "yes" } }, { "uniprot_canonical_ac": "G3MXC0-1", "uniprot_ac": "G3MXC0", "uniprot_id": "G3MXC0_BOVIN", "mass": { "chemical_mass": 54259.0, "monoisotopic_mass": 54259.0 }, "refseq": { "ac": "XP_024852755", "name": "transmembrane protein 200A isoform X2", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_024852755" }, "gene_names": [ { "name": "TMEM200A", "type": "recommended", "evidence": [ { "id": "G3MXC0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3MXC0" } ] }, { "name": "TMEM200A", "type": "synonym", "evidence": [ { "id": "XP_024852755", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_024852755" } ] } ], "protein_names": [ { "name": "Transmembrane protein 200A", "type": "synonym", "evidence": [ { "id": "G3MXC0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3MXC0/entry#names_and_taxonomy" } ] }, { "name": "transmembrane protein 200A isoform X2", "type": "synonym", "evidence": [ { "id": "XP_024852755", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_024852755" } ] } ], "function": [], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Bos taurus", "taxid": 9913, "evidence": [ { "database": "UniProtKB", "id": "G3MXC0", "url": "https://www.uniprot.org/uniprotkb/G3MXC0" } ], "common_name": "Bovine", "glygen_name": "Bovine", "reference_species": "Bos taurus [9913]" } ], "gene": [ { "name": "TMEM200A", "url": "https://www.uniprot.org/uniprotkb/G3MXC0", "locus": { "chromosome": "9", "start_pos": 68540889, "end_pos": 68454057, "strand": "-", "evidence": [ { "database": "Ensembl Gene", "id": "ENSBTAG00000040543", "url": "https://www.ensembl.org/id/ENSBTAG00000040543" } ] } } ], "crossref": [ { "id": "ENSBTAG00000040543", "url": "https://bgee.org/?page=gene&gene_id=ENSBTAG00000040543", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "112448061", "url": "https://www.ncbi.nlm.nih.gov/gene/112448061", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR018787", "url": "https://www.ebi.ac.uk/interpro/entry/IPR018787", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "bta:112448061", "url": "https://www.genome.jp/dbget-bin/www_bget?bta:112448061", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "FQPVSTM", "url": "https://omabrowser.org/oma/group/FQPVSTM/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "G3MXC0", "url": "https://www.orthodb.org/?gene=G3MXC0", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR31815", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR31815", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR31815:SF0", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR31815:SF0", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF10177", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF10177", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "XP_024852755", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_024852755", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "G3MXC0", "url": "https://www.uniprot.org/uniprotkb/G3MXC0", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "G3MXC0-1", "url": "https://www.uniprot.org/uniprotkb/G3MXC0-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MIATGGVITGLAALKRQDSARSQHHDNLSPSPAAQEKKPVRRRPRADVVVVRGKIRLYSPSGFFLILGVLISIVGIAMAVLGYWPQKEHFIDAETTLSTNETQVIRNQGGVVVHFFEQHLHSDKMKMLGPFTMGIGIFIFICANAILHENRDKETKIIHMRDIYSTVIDIHTLRIKEQKHMNGIYTGLMGETEVKQNGNSCASRLAANTIASFSGFRSSFRMDSSVEEDELVVNESKSFGHLVPPLLSDSSASVCGLYPPPSKTTDDKTSGPKKCETKSIVSSSISAFTLPVIKLNNCVIDEPSIDNITEDADNLKSRSRNLSMDSLMVPLPNPSQPFQPVSLMLPRNNSVGESLSSQYKSSVALGPGAGQLLSPGAARRQFGSNTSLHLLSSHSKSLDLERGHSTLTVQAEQRKHPSWPRLDRSNSKGYVKLENKEDPMERLLVPQAAIKKDFTNKEKLLMISRSHNNLSFEHDEFLSNNLKRGTSETRF", "length": 491, "header": "tr|G3MXC0-1|G3MXC0_BOVIN Isoform 1 of Transmembrane protein 200A OS=Bos taurus OX=9913 GN=TMEM200A PE=3 SV=1 CANONICAL=G3MXC0-1" }, "isoforms": [ { "isoform_ac": "G3MXC0-1", "url": "https://www.uniprot.org/uniprotkb/G3MXC0/entry", "sequence": { "sequence": "MIATGGVITGLAALKRQDSARSQHHDNLSPSPAAQEKKPVRRRPRADVVVVRGKIRLYSPSGFFLILGVLISIVGIAMAVLGYWPQKEHFIDAETTLSTNETQVIRNQGGVVVHFFEQHLHSDKMKMLGPFTMGIGIFIFICANAILHENRDKETKIIHMRDIYSTVIDIHTLRIKEQKHMNGIYTGLMGETEVKQNGNSCASRLAANTIASFSGFRSSFRMDSSVEEDELVVNESKSFGHLVPPLLSDSSASVCGLYPPPSKTTDDKTSGPKKCETKSIVSSSISAFTLPVIKLNNCVIDEPSIDNITEDADNLKSRSRNLSMDSLMVPLPNPSQPFQPVSLMLPRNNSVGESLSSQYKSSVALGPGAGQLLSPGAARRQFGSNTSLHLLSSHSKSLDLERGHSTLTVQAEQRKHPSWPRLDRSNSKGYVKLENKEDPMERLLVPQAAIKKDFTNKEKLLMISRSHNNLSFEHDEFLSNNLKRGTSETRF", "length": 491, "header": "tr|G3MXC0-1|G3MXC0_BOVIN Isoform 1 of Transmembrane protein 200A OS=Bos taurus OX=9913 GN=TMEM200A PE=3 SV=1 CANONICAL=G3MXC0-1" }, "locus": { "chromosome": "9", "start_pos": 68539139, "end_pos": 68537667, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000053029.4", "url": "https://www.ensembl.org/id/ENSBTAT00000053029.4" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000054185.1", "url": "https://www.ensembl.org/id/ENSBTAP00000054185.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [ { "id": "bta:112448061", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?bta:112448061", "resource": "KEGG Pathway" } ], "orthologs": [ { "uniprot_canonical_ac": "E1BT36-1", "protein_name": "Transmembrane protein 200A", "gene_name": "TMEM200A", "tax_id": 9031, "organism": "Gallus gallus", "sequence": { "sequence": "MIATGGVITGLAALKRQDSARSQQHVNLAAAPASEEKKPVRRRPRADVVIVRGKIRLYSPSGFFLVLGVLIAFLGIAMAILGYWPQKEQLLASEDSVSVNETQVLRNQGSILLRFFEQHVHSDKMKMLGPFTMGIGIFIFICANAILHENRDKETKIIHMRDIYSTVIDIHTLRIKEQKQLSGAFAGLLGEGELRHSGSSCASRLAANTVAPFSGFKSSFRMDSSAEEDEITLNEDRTTASLLPPLLTEQSGSVFGLYPHSSKASDDKNTSSIKCETKSIVSSSISAFTLPVIKLNNCVIDEPSIDNITEDSEITRSRSRNISMDSLAIPLTDTDESCKPAMLPRHNSFVDTQHDQFKSSMTLGPSTGKLLSPGAARKQFGSNTSLHLLSSHSKSLDLDRGPSTLTVQAEQRKHPSWPRLDRSNSKGYMKLENKEDPMDRLLVPQAVVKKDFTNKEKLLMISRSHNNLSFEHDEFLSNNLKRGTSETRF", "length": 489 }, "evidence": [ { "id": "G3MXC0", "url": "https://omabrowser.org/oma/group/G3MXC0/", "database": "OMA" } ], "glygen_name": "Chicken", "common_name": "Chicken" }, { "uniprot_canonical_ac": "F1S3M7-1", "protein_name": "Transmembrane protein 200A", "gene_name": "TMEM200A", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MIATGGVITGLAALKRQDSARSQHHVNLSPSPAAQEKKPVRRRPRADVVVVRGKIRLYSPSGFFLILGVLISIVGIAMAVLGYWPQKEHFIDAETTLSTNETEVIRNQGGVVVRFFEQHLHSDKMKMLGPFTMGIGIFIFICANAILHENRDKETKIIHMRDIYSTVIDIHTLRIKEQKHMNGIYTGLMGETEVKQNGNSCASRLAANTIASFSGFRSSFRMDSSVEEDELVINESKSLGHLIPPLLSDNSASVCGLYPPPSKTAEDKSSGPKKCETKSIVSSSISAFTLPVIKLNNCVIDEPSIDNITEDADTLKSRSRNLSMDSLMLPLPNSSQPFQPVSMILPRNNSIGESLSSQYKSSVALGPGAGQLLSPGAARRQFGSNTSLHLLSSHSKSLDLDRGPSTLTVQAEQRKHPSWPRLDRSNSKGYMKLENKEDPVERLLVPQAAVKKDFTNKEKLLMISRSHNNLSFEHDEFLSNNLKRGTSETRF", "length": 491 }, "evidence": [ { "id": "G3MXC0", "url": "https://omabrowser.org/oma/group/G3MXC0/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "G3IP88-1", "protein_name": "Transmembrane protein 200A", "gene_name": "Tmem200a", "tax_id": 10029, "organism": "Cricetulus griseus", "sequence": { "sequence": "MIATGGVITGLAALKRQDSARSQQHVNLSPAPAAQDQKPVRRRPRADVVVVRGKIRLYSPSGFFLILGVLVSIIGIAMAVLGYWPQKEHFIDAETTLSTNETQVVRNQGGVVVRFFEQHLHSDKMKMLGPFTMGIGIFIFICANAILHENRDKETKIIHMRDIYSTVIDIHTLRLKEQKQANGLYAGLLGDVEVKQNGSPCASRLAATTLASFSGLRNSFRVDSSVEEDELMLSESKSLGHLMPPLLSDSAVSVFGLYPPPSKTTDDKTSSSKKCDTKSIVSSSISAFTLPVIKLNNCVIDEPGIDSITEVADNLKSRSRNLSMDSLMVPLPSSGEAFQPSSTLLPRNNSVGESLSSQYKSSVALGPGTGQLLSPGAARRQFGSNTSLHFLSSHSKSLDLERGPSTLTVQAEQRKHPSWPRLDRSNSKGYMKLENKEDPMDRLLVPQTAIKKDFTNKEKLLMISRSHNNLSFEHDEFLSNNLKRGTSETRF", "length": 491 }, "evidence": [ { "id": "G3MXC0", "url": "https://omabrowser.org/oma/group/G3MXC0/", "database": "OMA" } ], "glygen_name": "Hamster", "common_name": "Chinese hamster" }, { "uniprot_canonical_ac": "Q5RGQ8-1", "protein_name": "Transmembrane protein 200A", "gene_name": "tmem200a", "tax_id": 7955, "organism": "Danio rerio", "sequence": { "sequence": "MIATGGVITGLAALKRQDSTRSQYHLSAQSPGPAPEKKTTKRKPRADVVVVRGKIRLYSASGFFLVLGVLILMAGIAMAVLGYWPHKDQPKAPETKMSANNTQSFGREQAGSIAQFLEQHMHSEKMKMLGPFTMGIGIFIFICANAILHENRDRETKVIHMRDMYSTVIDIHSLRIKEQKCTNGACMGPYGGDTEIRTFGLDSQFASRLAANTLMSFSGLDGDVRFSHRTSSADDDDGLMSEARGGFCLLSPTYKDRSECIFGFQDDGRWEDRRGALKKCQTRSIVSSSISAFTLPVIKLNNCVIDEPDIDSITEDLEQSRVHSRPPSMESLTVPVPDIAKAFKPPGVQLLRSNSATESASSTSSRSSLSPGSTSGRFLSPGAARKDFGSNNSIHMLSAHSKSLDLERGPTKLTVQPEQRKHPSWPRLDRSNSKGYTRLENKEDPMDRLIVPPVDVKKDYTKKEKLLMISRSHNNLSFEHDEFMSSGLKRGTSETRF", "length": 497 }, "evidence": [ { "id": "G3MXC0", "url": "https://omabrowser.org/oma/group/G3MXC0/", "database": "OMA" } ], "glygen_name": "Zebrafish", "common_name": "Zebrafish" }, { "uniprot_canonical_ac": "Q86VY9-1", "protein_name": "Transmembrane protein 200A", "gene_name": "TMEM200A", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MIATGGVITGLAALKRQDSARSQQHVNLSPSPATQEKKPIRRRPRADVVVVRGKIRLYSPSGFFLILGVLISIIGIAMAVLGYWPQKEHFIDAETTLSTNETQVIRNEGGVVVRFFEQHLHSDKMKMLGPFTMGIGIFIFICANAILHENRDKETKIIHMRDIYSTVIDIHTLRIKEQRQMNGMYTGLMGETEVKQNGSSCASRLAANTIASFSGFRSSFRMDSSVEEDELMLNEGKSSGHLMPPLLSDSSVSVFGLYPPPSKTTDDKTSGSKKCETKSIVSSSISAFTLPVIKLNNCVIDEPSIDNITEDADNLKSRSRNLSMDSLVVPLPNTSESFQPVSTVLPRNNSIGESLSSQYKSSMALGPGAGQLLSPGAARRQFGSNTSLHLLSSHSKSLDLDRGPSTLTVQAEQRKHPSWPRLDRNNSKGYMKLENKEDPMDRLLVPQVAIKKDFTNKEKLLMISRSHNNLSFEHDEFLSNNLKRGTSETRF", "length": 491 }, "evidence": [ { "id": "G3MXC0", "url": "https://omabrowser.org/oma/group/G3MXC0/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "Q8C817-1", "protein_name": "Transmembrane protein 200A", "gene_name": "Tmem200a", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MIATGGVITGLAALKRQDSARSQQHINLSPLPATQDQKPVRRRPRADVVVVRGKIRLYSPSGFFLILGVLVSIIGIAMAVLGYWPQKEHFIDAETTLSTNETQVVRNQGGVVVRFFEQHLHSDKMKMLGPFTMGIGIFIFICANAILHENRDKETKIIHMRDIYSTVIDIHTLRLKEQKQANGLYAGLLGDTEVKQNGSPCASRLAATTLASFSGMRNSFRVDSSVEEDELMLTESKSLGHLMPPLLSDSAVSVFGLYPPPAKATDDKASSSKKCDTKSIVSSSISAFTLPVIKLNNCVIDEPSIDSITEVADNLKTRSRNLSMDSLVVPLPSSGESFQPAVTLLPRNNSVGESLSSQYKSSVALGPGTGQLLSPGAARRQFGSNTSLHLLSSHSKSLDLDRGPSTLTVHAEQRKHPSWPRLDRSNSKGYMRLENKEDPMDRLLVPQTAIKKDFTNKEKLLMISRSHNNLSFEHDEFLSNNLKRGTSETRF", "length": 491 }, "evidence": [ { "id": "G3MXC0", "url": "https://omabrowser.org/oma/group/G3MXC0/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" } ], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 1, "go_terms": [ { "name": "membrane", "id": "GO:0016020", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016020", "evidence": [ { "database": "UniProtKB", "id": "G3MXC0", "url": "https://www.uniprot.org/uniprotkb/G3MXC0" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 100, "end_pos": 102, "annotation": "n_glycosylation_sequon" }, { "start_pos": 234, "end_pos": 236, "annotation": "n_glycosylation_sequon" }, { "start_pos": 27, "end_pos": 29, "annotation": "n_glycosylation_sequon" }, { "start_pos": 307, "end_pos": 309, "annotation": "n_glycosylation_sequon" }, { "start_pos": 321, "end_pos": 323, "annotation": "n_glycosylation_sequon" }, { "start_pos": 348, "end_pos": 350, "annotation": "n_glycosylation_sequon" }, { "start_pos": 385, "end_pos": 387, "annotation": "n_glycosylation_sequon" }, { "start_pos": 469, "end_pos": 471, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "homologset.oma", "label": "OMA Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 100, "end_pos": 102 }, { "start_pos": 234, "end_pos": 236 }, { "start_pos": 27, "end_pos": 29 }, { "start_pos": 307, "end_pos": 309 }, { "start_pos": 321, "end_pos": 323 }, { "start_pos": 348, "end_pos": 350 }, { "start_pos": 385, "end_pos": 387 }, { "start_pos": 469, "end_pos": 471 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ], "tool_support": { "graph_view": "yes" } }, { "uniprot_canonical_ac": "G3MXD8-1", "uniprot_ac": "G3MXD8", "uniprot_id": "G3MXD8_BOVIN", "mass": { "chemical_mass": 20696.0, "monoisotopic_mass": 20696.0 }, "refseq": { "ac": "NP_001139125", "name": "uncharacterized protein C6orf141 homolog", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001139125" }, "gene_names": [ { "name": "C23H6orf141", "type": "recommended", "evidence": [ { "id": "G3MXD8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3MXD8" } ] }, { "name": "C23H6orf141", "type": "synonym", "evidence": [ { "id": "NP_001139125", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001139125" } ] } ], "protein_names": [ { "name": "Chromosome 23 C6orf141 homolog", "type": "synonym", "evidence": [ { "id": "G3MXD8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3MXD8/entry#names_and_taxonomy" } ] }, { "name": "uncharacterized protein C6orf141 homolog", "type": "synonym", "evidence": [ { "id": "NP_001139125", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001139125" } ] } ], "function": [], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Bos taurus", "taxid": 9913, "evidence": [ { "database": "UniProtKB", "id": "G3MXD8", "url": "https://www.uniprot.org/uniprotkb/G3MXD8" } ], "common_name": "Bovine", "glygen_name": "Bovine", "reference_species": "Bos taurus [9913]" } ], "gene": [ { "name": "C23H6orf141", "url": "https://www.uniprot.org/uniprotkb/G3MXD8", "locus": { "chromosome": "23", "start_pos": 22327665, "end_pos": 22323297, "strand": "-", "evidence": [ { "database": "Ensembl Gene", "id": "ENSBTAG00000047591", "url": "https://www.ensembl.org/id/ENSBTAG00000047591" } ] } } ], "crossref": [ { "id": "G3MXD8", "url": "https://alphafold.ebi.ac.uk/entry/G3MXD8", "database": "AlphaFoldDB", "categories": [] }, { "id": "ENSBTAG00000047591", "url": "https://bgee.org/?page=gene&gene_id=ENSBTAG00000047591", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "100271839", "url": "https://www.ncbi.nlm.nih.gov/gene/100271839", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR037739", "url": "https://www.ebi.ac.uk/interpro/entry/IPR037739", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "bta:100271839", "url": "https://www.genome.jp/dbget-bin/www_bget?bta:100271839", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "VRIVDYQ", "url": "https://omabrowser.org/oma/group/VRIVDYQ/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "G3MXD8", "url": "https://www.orthodb.org/?gene=G3MXD8", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR36880", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR36880", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR36880:SF1", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR36880:SF1", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "NP_001139125", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001139125", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "G3MXD8", "url": "https://www.uniprot.org/uniprotkb/G3MXD8", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "G3MXD8-1", "url": "https://www.uniprot.org/uniprotkb/G3MXD8-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MNGPHTGMGAPGPRGAPDLADSPRSEQRCQQFALEAGRWAPSAPGARNLWAAESSRRQGGAHEDREVGENADCDSWVRDKVLFLLHPERWLGTKGDAAPEEVADEEDLFKAQGQDREPNCSSPLFPRKIRISGSRVDAPSRAPKPLLVRVLDYEVTQEVLEVAWAKGSMTTLTEERSMTAVTFRTNTE", "length": 188, "header": "tr|G3MXD8-1|G3MXD8_BOVIN Isoform 1 of Chromosome 23 C6orf141 homolog OS=Bos taurus OX=9913 GN=C23H6orf141 PE=4 SV=1 CANONICAL=G3MXD8-1" }, "isoforms": [ { "isoform_ac": "G3MXD8-1", "url": "https://www.uniprot.org/uniprotkb/G3MXD8/entry", "sequence": { "sequence": "MNGPHTGMGAPGPRGAPDLADSPRSEQRCQQFALEAGRWAPSAPGARNLWAAESSRRQGGAHEDREVGENADCDSWVRDKVLFLLHPERWLGTKGDAAPEEVADEEDLFKAQGQDREPNCSSPLFPRKIRISGSRVDAPSRAPKPLLVRVLDYEVTQEVLEVAWAKGSMTTLTEERSMTAVTFRTNTE", "length": 188, "header": "tr|G3MXD8-1|G3MXD8_BOVIN Isoform 1 of Chromosome 23 C6orf141 homolog OS=Bos taurus OX=9913 GN=C23H6orf141 PE=4 SV=1 CANONICAL=G3MXD8-1" }, "locus": { "chromosome": "23", "start_pos": 22327665, "end_pos": 22327244, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000063844.2", "url": "https://www.ensembl.org/id/ENSBTAT00000063844.2" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000054203.1", "url": "https://www.ensembl.org/id/ENSBTAP00000054203.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [ { "id": "bta:100271839", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?bta:100271839", "resource": "KEGG Pathway" } ], "orthologs": [ { "uniprot_canonical_ac": "Q5SZD1-1", "protein_name": "Uncharacterized protein C6orf141", "gene_name": "C6orf141", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MNDPFARMETRGPQGAANPMDSSRSLGDLGPFPREVGRGAPLAPGARNPATAGASRSQGGGHEDRTADRALGPRAGEELDRESWVREKVLFLLHPERWLGTRGDPAREEVAGAEDLPHAGGEDHGEEPNYPSVFQRQKRISGRRVAPPRDAADPPKYVLVRVEDYQVTQEVLQTSWAKGRMTTRTEEHFVTALTFRSSREGQPGERWGPAESRALQARTGASRVHAAGRRVSPSPGTWLEEIKL", "length": 244 }, "evidence": [ { "id": "G3MXD8", "url": "https://omabrowser.org/oma/group/G3MXD8/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" } ], "go_annotation": {}, "pro_annotation": [], "site_annotation": [ { "start_pos": 119, "end_pos": 121, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [ { "pdb_id": "AF-G3MXD8-F1", "pdb_chain": "global", "start_pos": 1, "end_pos": 188, "overlap": "1.0", "method": "AlphaFold", "type": "alphafold", "resolution": -1.0, "url": "https://data.glygen.org/ln2downloads/pdb/current/AF-G3MXD8-F1.pdb", "url_external": 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"url": "https://www.uniprot.org/uniprotkb/G3MXE3" } ] }, { "name": "LOC785756", "type": "synonym", "evidence": [ { "id": "NP_001193735", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001193735" } ] } ], "protein_names": [ { "name": "Uncharacterized protein", "type": "synonym", "evidence": [ { "id": "G3MXE3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3MXE3/entry#names_and_taxonomy" } ] }, { "name": "androgen binding protein beta-like precursor", "type": "synonym", "evidence": [ { "id": "NP_001193735", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001193735" } ] }, { "name": "salivary androgen-binding protein beta subunit-like", "type": "synonym", "evidence": [ { "id": "NP_001193735", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001193735" } ] } ], "function": [], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Bos 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"MMKGALLVLTLLVTRELTFKTTDACPVFYGGVAALLLGSKTVLNSTLDLVDSTDEEKAAFGKVQDCFNEAGFDAKLKVVEIMGSIVFDKDCTGYQVSTVLSSVFGIVLSAVSLVK", "length": 115, "header": "tr|G3MXE3-1|G3MXE3_BOVIN Isoform 1 of Uncharacterized protein OS=Bos taurus OX=9913 GN=LOC785756 PE=3 SV=2 CANONICAL=G3MXE3-1" }, "isoforms": [ { "isoform_ac": "G3MXE3-1", "url": "https://www.uniprot.org/uniprotkb/G3MXE3/entry", "sequence": { "sequence": "MMKGALLVLTLLVTRELTFKTTDACPVFYGGVAALLLGSKTVLNSTLDLVDSTDEEKAAFGKVQDCFNEAGFDAKLKVVEIMGSIVFDKDCTGYQVSTVLSSVFGIVLSAVSLVK", "length": 115, "header": "tr|G3MXE3-1|G3MXE3_BOVIN Isoform 1 of Uncharacterized protein OS=Bos taurus OX=9913 GN=LOC785756 PE=3 SV=2 CANONICAL=G3MXE3-1" }, "locus": { "chromosome": "18", "start_pos": 45133627, "end_pos": 45131601, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000065560.2", "url": "https://www.ensembl.org/id/ENSBTAT00000065560.2" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000054209.2", "url": 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"PTHR15718:SF5", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR15718:SF5", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF15235", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF15235", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "NP_001192712", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001192712", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "G3MXF1", "url": "https://www.uniprot.org/uniprotkb/G3MXF1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "G3MXF1-1", "url": "https://www.uniprot.org/uniprotkb/G3MXF1-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MRSSRPEPDAPEPLSAHPQPLSRSSSSLLGEGRGQRPEYRKRASSTVCQAQLGEAGTGAQVPEAEGQQAERVEQAQASSPQLQPSAVGHWRSSTVGNVSTVGGSDLCNPWDPSAAAVQRSHSDLAHSTQTRGHSGAQKASLSCSALGSLPVHGAQLQPSSTSGQSGQTPEGLERDLAPEDKTSNSAWTLESQVWVPPAALGGTVTHSSSPKATGQSATTSCHALSPAALLCGMREVGASSCCHGLPAPGILAFPKLVASVSESRLQAHHGVKLQCRFSGGLPGHSHCCAHPWGPTGLAMEPSARTKDMWTMTSASDLAPVLASPLSAQDAGVQAAPKAVCKAVATSPPLEAPVALRMFPEVTLEPSLAEAPSPVRDVRWDAEGMTWEVYGAAVDPEVLGVAIQKHLEMQFEQLQGAPASEDSLSAEGRRGPLRAVMQSLRHPSCCGCSSAAPE", "length": 453, "header": "tr|G3MXF1-1|G3MXF1_BOVIN Isoform 1 of G protein regulated inducer of neurite outgrowth 2 OS=Bos taurus OX=9913 GN=GPRIN2 PE=4 SV=2 CANONICAL=G3MXF1-1" }, "isoforms": [ { "isoform_ac": "G3MXF1-1", "url": "https://www.uniprot.org/uniprotkb/G3MXF1/entry", "sequence": { "sequence": "MRSSRPEPDAPEPLSAHPQPLSRSSSSLLGEGRGQRPEYRKRASSTVCQAQLGEAGTGAQVPEAEGQQAERVEQAQASSPQLQPSAVGHWRSSTVGNVSTVGGSDLCNPWDPSAAAVQRSHSDLAHSTQTRGHSGAQKASLSCSALGSLPVHGAQLQPSSTSGQSGQTPEGLERDLAPEDKTSNSAWTLESQVWVPPAALGGTVTHSSSPKATGQSATTSCHALSPAALLCGMREVGASSCCHGLPAPGILAFPKLVASVSESRLQAHHGVKLQCRFSGGLPGHSHCCAHPWGPTGLAMEPSARTKDMWTMTSASDLAPVLASPLSAQDAGVQAAPKAVCKAVATSPPLEAPVALRMFPEVTLEPSLAEAPSPVRDVRWDAEGMTWEVYGAAVDPEVLGVAIQKHLEMQFEQLQGAPASEDSLSAEGRRGPLRAVMQSLRHPSCCGCSSAAPE", "length": 453, "header": "tr|G3MXF1-1|G3MXF1_BOVIN Isoform 1 of G protein regulated inducer of neurite outgrowth 2 OS=Bos taurus OX=9913 GN=GPRIN2 PE=4 SV=2 CANONICAL=G3MXF1-1" }, "locus": { "chromosome": "28", "start_pos": 41807283, "end_pos": 41805925, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000095372.1", "url": "https://www.ensembl.org/id/ENSBTAT00000095372.1" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000094167.1", "url": "https://www.ensembl.org/id/ENSBTAP00000094167.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [ { "id": "bta:540175", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?bta:540175", "resource": "KEGG Pathway" } ], "orthologs": [ { "uniprot_canonical_ac": "A0A2I3BRN2-1", "protein_name": "G protein regulated inducer of neurite outgrowth 2", "gene_name": "Gprin2", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MSSSHPEPGAREPQSPRPQALSQSSSSLLCEGREQKPELRKSASSTVWRAQQGEAGSSPRILQEEACQTEIPEHAQTASTASQAGAGGHWRSSTVGNVSTMGIGDLCRLRAPSVAAVQRSHSDLVHSTQTRGHGGVQKPSLSCSALGSSPVHRAQLQPGSVAGQGGQTPAPLQSDSAPEDGTSKSACTLGESQVWVPTVELEDATGLLRGPQGEPKATGQPPTTSCHALPPAALLCTLGEAVAGSCCHALPARGILAFPKLVASVSESGLQAQCGMKFHCKLSGGISGHPHCCVHPWGPTGLATESGSRTKDVWTMTSATDLALGVASAQDAGVQAAPAAACKAVATSPSLEAPETLNLFPEVMLESGLRQASSPVRDVRWDAEGMTWEVYGASVDPEVLGIAIQKHLEMQFEQLQQAPASEDSLSAEGRRGPLRAVMQSLRRPSCCGCSGAAPE", "length": 455 }, "evidence": [ { "id": "G3MXF1", "url": "https://omabrowser.org/oma/group/G3MXF1/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "A0A8C2LQJ1-1", "protein_name": "G protein-regulated inducer of neurite outgrowth 2", "gene_name": "Gprin2", "tax_id": 10029, "organism": "Cricetulus griseus", "sequence": { "sequence": "MSSSHPEPGARESQSPRPQPLSQSSSSLLCEGREQRPELRKSASSTVWQAQPGEASPSPRTLEEEGCQTESMDQAQTSSPWPQPGAGGHWRSSTVGNVSTMGIGDLCRLRAPSVAAVQRSHSDLVHSTQTRGHGSAQKASLSCSALGSSPVQTAQLQLGSVAGQDGQTPGVLQSDLAPEDGTSTSACILGESQVLVPTVELEGTAGLISSPQGGPKATGQPPTTSCQVLPPAALLCTVRETASGGCYHALPATGILAFPKLVASVSESGLQAQCGMKFHCKLPGGISGHPHCCVHPWGPTGLATESGSRTKDVWTMTSATDLALGVASAQDAGVQVAPVAACKAVATSPSLEEPETQNIFPEVMLGAGLEKASSPVREVRWDAEGMTWEVYGASVDPEVLGIAIQKHLEMQFEQLQQAPASEDSLSTEGRRGPLRAVMQSLRRPSCCGCSGAAPE", "length": 455 }, "evidence": [ { "id": "G3MXF1", "url": "https://omabrowser.org/oma/group/G3MXF1/", "database": "OMA" } ], "glygen_name": "Hamster", "common_name": "Chinese hamster" }, { "uniprot_canonical_ac": "D3ZH78-1", "protein_name": "G protein regulated inducer of neurite outgrowth 2", "gene_name": "Gprin2", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MSSSHPEPGAREPQSPRPQPLSQSSSSLLCEGREQRPELRKSVSSTVWRAQQAEASTGPRTLQEEGCQMESTEQAQTANPPSQAAAGGHWRSSTVGNVSTMGIGDLCRLQAPSVAAVQRSHSDLVHSTQTRGHGSVQKPSLSCSALGISPVHRAHLQPGGVAGQGGPTPAPLPSDSSLEDGTSKSACTLGESQVWVPTIELEDTTGLLIGSQGEPQATGQPSTTPCHALPPATLLCTVGEAVPGSTCHALPAKGILAFPKLVASVSESGLQAQCGMKFHCQLSGGISGRAHCCVHPWGPTGLATESGSRTKDVWTMTSATDLALGVASAQDAGVQAAPVAACKAVATSPSLEAPKTLNIFPEVMLGPGLEEASSPVREVRWDAEGMTWEVYGASVDPEVLGIAIQKHLEMQFEQLQQAPASEDSLSTEGRRGPLRAVMQSLRRPSCCGCSGAAPE", "length": 455 }, "evidence": [ { "id": "G3MXF1", "url": "https://omabrowser.org/oma/group/G3MXF1/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "O60269-1", "protein_name": "G protein-regulated inducer of neurite outgrowth 2", "gene_name": "GPRIN2", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MSSSRPEPGPWAPLSPRLQPLSQSSSSLLGEGREQRPELRKTASSTVWQAQLGEASTRPQAPEEEGNPPESMKPARASGPKARPSAGGHWWSSTVGNVSTMGGSDLCRLRAPSAAAMQRSHSDLVRSTQMRGHSGARKASLSCSALGSSPVHRAQLQPGGTSGQGGQAPAGLERDLAPEDETSNSAWMLGASQLSVPPLDLGDTTAHSSSAQAEPKAAEQLATTTCHALPPAALLCGMREVRAGGCCHALPATGILAFPKLVASVSESGLQAQHGVKIHCRLSGGLPGHSHCCAHLWGPAGLVPEPGSRTKDVWTMTSANDLAPAEASPLSAQDAGVQAAPVAACKAVATSPSLEAPAALHVFPEVTLGSSLEEVPSPVRDVRWDAEGMTWEVYGAAVDLEVLGVAIQKHLEMQFEQLQRAPASEDSLSVEGRRGPLRAVMQSLRRPSCCGCSGAAPE", "length": 458 }, "evidence": [ { "id": "G3MXF1", "url": "https://omabrowser.org/oma/group/G3MXF1/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" } ], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 1, "go_terms": [ { "name": "plasma membrane", "id": "GO:0005886", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005886", "evidence": [ { "database": "UniProtKB", "id": "G3MXF1", "url": "https://www.uniprot.org/uniprotkb/G3MXF1" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 1, "go_terms": [ { "name": "neuron projection development", "id": "GO:0031175", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0031175", "evidence": [ { "database": "UniProtKB", "id": "G3MXF1", "url": "https://www.uniprot.org/uniprotkb/G3MXF1" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 97, "end_pos": 99, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "G3MXF1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3MXF1" }, { "id": "PF15235", "database": "Pfam", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF15235" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "G protein-regulated inducer of neurite outgrowth C-terminal", "eco_id": "ECO_0000259", "start_pos": 368, "end_pos": 446, "start_aa": "Ala", "end_aa": "Gly", "glycosite_overlap": [] } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "homologset.oma", "label": "OMA Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 97, "end_pos": 99 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ], "tool_support": { "graph_view": "yes" } }, { "uniprot_canonical_ac": "G3MXF2-1", "uniprot_ac": "G3MXF2", "uniprot_id": "G3MXF2_BOVIN", "mass": { "chemical_mass": 12151.0, "monoisotopic_mass": 12151.0 }, "refseq": { "ac": "XP_059739774", "name": "transcription elongation factor A protein-like 7", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_059739774" }, "gene_names": [ { "name": "TCEAL7", "type": "recommended", "evidence": [ { "id": "G3MXF2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3MXF2" } ] }, { "name": "TCEAL7", "type": "synonym", "evidence": [ { "id": "XP_059739774", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_059739774" } ] } ], "protein_names": [ { "name": "Transcription elongation factor A like 7", "type": "synonym", "evidence": [ { "id": "G3MXF2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3MXF2/entry#names_and_taxonomy" } ] }, { "name": "transcription elongation factor A protein-like 7", "type": "synonym", "evidence": [ { "id": "XP_059739774", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_059739774" } ] } ], "function": [], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Bos taurus", "taxid": 9913, "evidence": [ { "database": "UniProtKB", "id": "G3MXF2", "url": "https://www.uniprot.org/uniprotkb/G3MXF2" } ], "common_name": "Bovine", "glygen_name": "Bovine", "reference_species": "Bos taurus [9913]" } ], "gene": [ { "name": "TCEAL7", "url": "https://www.uniprot.org/uniprotkb/G3MXF2", "locus": { "chromosome": "X", "start_pos": 51988730, "end_pos": 51990145, "strand": "+", "evidence": [ { "database": "Ensembl Gene", "id": "ENSBTAG00000046707", "url": "https://www.ensembl.org/id/ENSBTAG00000046707" } ] } } ], "crossref": [ { "id": "G3MXF2", "url": "https://alphafold.ebi.ac.uk/entry/G3MXF2", "database": "AlphaFoldDB", "categories": [] }, { "id": "ENSBTAG00000046707", "url": "https://bgee.org/?page=gene&gene_id=ENSBTAG00000046707", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "100138330", "url": "https://www.ncbi.nlm.nih.gov/gene/100138330", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR021156", "url": "https://www.ebi.ac.uk/interpro/entry/IPR021156", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "bta:100138330", "url": "https://www.genome.jp/dbget-bin/www_bget?bta:100138330", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "DYRHFKG", "url": "https://omabrowser.org/oma/group/DYRHFKG/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "G3MXF2", "url": "https://www.orthodb.org/?gene=G3MXF2", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PF04538", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF04538", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "XP_059739774", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_059739774", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "G3MXF2", "url": "https://www.uniprot.org/uniprotkb/G3MXF2", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "G3MXF2-1", "url": "https://www.uniprot.org/uniprotkb/G3MXF2-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MQKSCKENEGTPKCNVPKRQEERSYGEFQRQQTEGNFRQRLLQSLEEFKEDIDFRHFKDEGMTREGDGMERCLEEIRGLRKKFRALLSNRKHFRDHPYPI", "length": 100, "header": "tr|G3MXF2-1|G3MXF2_BOVIN Isoform 1 of Transcription elongation factor A like 7 OS=Bos taurus OX=9913 GN=TCEAL7 PE=4 SV=1 CANONICAL=G3MXF2-1" }, "isoforms": [ { "isoform_ac": "G3MXF2-1", "url": "https://www.uniprot.org/uniprotkb/G3MXF2/entry", "sequence": { "sequence": "MQKSCKENEGTPKCNVPKRQEERSYGEFQRQQTEGNFRQRLLQSLEEFKEDIDFRHFKDEGMTREGDGMERCLEEIRGLRKKFRALLSNRKHFRDHPYPI", "length": 100, "header": "tr|G3MXF2-1|G3MXF2_BOVIN Isoform 1 of Transcription elongation factor A like 7 OS=Bos taurus OX=9913 GN=TCEAL7 PE=4 SV=1 CANONICAL=G3MXF2-1" }, "locus": { "chromosome": "X", "start_pos": 51989098, "end_pos": 51988799, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000065539.3", "url": "https://www.ensembl.org/id/ENSBTAT00000065539.3" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000054218.1", "url": "https://www.ensembl.org/id/ENSBTAP00000054218.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [ { "id": "bta:100138330", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?bta:100138330", "resource": "KEGG Pathway" } ], "orthologs": [ { "uniprot_canonical_ac": "A0A8W4FEA0-1", "protein_name": "Transcription elongation factor A like 7", "gene_name": "TCEAL7", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MQKSCKENEGKSKCSVPKREEERPYGEFERQQTEGNFRQRLLQSLEEFKEDIDYRHFRDEEMTREGDEMERCLEEIRGLRRKFRALHSNYRHSRGGPYPI", "length": 100 }, "evidence": [ { "id": "G3MXF2", "url": "https://omabrowser.org/oma/group/G3MXF2/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "A3KGA4-1", "protein_name": "Transcription elongation factor A protein-like 7", "gene_name": "Tceal7", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MQKSCNEKEGKPKGSEAKREDEQPCGALEGQRLEGNFRQRLLQSLEEFKEDIDYRHFKGEEMTGEEEEMERCLEEIRSLRKKFRALHSNRTHSRDHPF", "length": 98 }, "evidence": [ { "id": "G3MXF2", "url": "https://omabrowser.org/oma/group/G3MXF2/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "D3ZT37-1", "protein_name": "Transcription elongation factor A protein-like 7", "gene_name": "Tceal7", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MQRSCNEKEGKPKCSEPKREEEHPYGAFEGQRLEGNFRQRLLQSLEEFKEDIDYRHFKGEEMTGEEEEMERCLEEIRSLRKKFRALHSNRTHSRDRPF", "length": 98 }, "evidence": [ { "id": "G3MXF2", "url": "https://omabrowser.org/oma/group/G3MXF2/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "Q9BRU2-1", "protein_name": "Transcription elongation factor A protein-like 7", "gene_name": "TCEAL7", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MQKPCKENEGKPKCSVPKREEKRPYGEFERQQTEGNFRQRLLQSLEEFKEDIDYRHFKDEEMTREGDEMERCLEEIRGLRKKFRALHSNHRHSRDRPYPI", "length": 100 }, "evidence": [ { "id": "G3MXF2", "url": "https://omabrowser.org/oma/group/G3MXF2/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" } ], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 1, "go_terms": [ { "name": "nucleoplasm", "id": "GO:0005654", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005654", "evidence": [ { "database": "UniProtKB", "id": "G3MXF2", "url": "https://www.uniprot.org/uniprotkb/G3MXF2" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 1, "go_terms": [ { "name": "negative regulation of DNA-templated transcription", "id": "GO:0045892", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0045892", "evidence": [ { "database": "UniProtKB", "id": "G3MXF2", "url": "https://www.uniprot.org/uniprotkb/G3MXF2" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [ { "pdb_id": "AF-G3MXF2-F1", "pdb_chain": "global", "start_pos": 1, "end_pos": 100, "overlap": "1.0", "method": "AlphaFold", "type": "alphafold", "resolution": -1.0, "url": "https://data.glygen.org/ln2downloads/pdb/current/AF-G3MXF2-F1.pdb", "url_external": "https://alphafold.ebi.ac.uk/entry/G3MXF2" } ], "lectin_list": [], "domain_list": [], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "homologset.oma", "label": "OMA Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { 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"end_pos": 1058869, "strand": "-", "evidence": [ { "database": "Ensembl Gene", "id": "ENSBTAG00000040360", "url": "https://www.ensembl.org/id/ENSBTAG00000040360" } ] } } ], "crossref": [ { "id": "G3MXG2", "url": "https://alphafold.ebi.ac.uk/entry/G3MXG2", "database": "AlphaFoldDB", "categories": [] }, { "id": "ENSBTAG00000040360", "url": "https://bgee.org/?page=gene&gene_id=ENSBTAG00000040360", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "IPR032777", "url": "https://www.ebi.ac.uk/interpro/entry/IPR032777", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "HHTRRQL", "url": "https://omabrowser.org/oma/group/HHTRRQL/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "PTHR14845", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR14845", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR14845:SF4", "url": 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"MAPKKKRGPGAGRRGGAAGEGTEPPLSERAQYLQREHKLLSEELEACKQRVDQVLQENDFLDSEAPRLREENRLYASYASTRAQRCANAIVRLEEQNRVSLSQIHWQRAELASIYRGREDGVRAQLLEMEARAAQMAQQVQELQPYKELQLEQLARIRALERELLHMRVEHTQLLHRVKRRFLEDKAAFEREARQRVQSLARRAEREAARALLAHTQAIRVDNGRLRQELLRLLRRAQVLQDTRRQLLEQREQLRREHEDTRDLARVHGWLRRGPEGPPLWEPSPAASDPESFPSKTPSNATFRVPSVPASHNPSQVLCRADSWTPSLPSKVSVPRVPSLVPSRVGTRVLSLAPSKASLRVPSHVGSRVQSLSVSRPGSRVPSLTPSGPGSGVASLTTDSQFSSRSSLRAASQNTILSGKLVPRSSSYPLPVEGDGDRDAADEAASGRA", "length": 449, "header": "tr|G3MXG2-1|G3MXG2_BOVIN Isoform 1 of Coiled-coil domain containing 166 OS=Bos taurus OX=9913 GN=CCDC166 PE=4 SV=1 CANONICAL=G3MXG2-1" }, "isoforms": [ { "isoform_ac": "G3MXG2-1", "url": "https://www.uniprot.org/uniprotkb/G3MXG2/entry", "sequence": { "sequence": "MAPKKKRGPGAGRRGGAAGEGTEPPLSERAQYLQREHKLLSEELEACKQRVDQVLQENDFLDSEAPRLREENRLYASYASTRAQRCANAIVRLEEQNRVSLSQIHWQRAELASIYRGREDGVRAQLLEMEARAAQMAQQVQELQPYKELQLEQLARIRALERELLHMRVEHTQLLHRVKRRFLEDKAAFEREARQRVQSLARRAEREAARALLAHTQAIRVDNGRLRQELLRLLRRAQVLQDTRRQLLEQREQLRREHEDTRDLARVHGWLRRGPEGPPLWEPSPAASDPESFPSKTPSNATFRVPSVPASHNPSQVLCRADSWTPSLPSKVSVPRVPSLVPSRVGTRVLSLAPSKASLRVPSHVGSRVQSLSVSRPGSRVPSLTPSGPGSGVASLTTDSQFSSRSSLRAASQNTILSGKLVPRSSSYPLPVEGDGDRDAADEAASGRA", "length": 449, "header": "tr|G3MXG2-1|G3MXG2_BOVIN Isoform 1 of Coiled-coil domain containing 166 OS=Bos taurus OX=9913 GN=CCDC166 PE=4 SV=1 CANONICAL=G3MXG2-1" }, "locus": { "chromosome": "14", "start_pos": 1060536, "end_pos": 1059097, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000055905.3", "url": "https://www.ensembl.org/id/ENSBTAT00000055905.3" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000054229.1", "url": "https://www.ensembl.org/id/ENSBTAP00000054229.1" } ] } } ], "glycosylation": [], 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"MAPKKKRGPSAGSQPGGAAAAGAEQPLSERAQYLQREHALLSEQLDTCEESVDQVLRENAFLDREALRLREENRLYASYVSARAQRCAKAIVRLDEQNRVDLAQIHWQRAELASLYHGREDGVRAQLLEMEARAAQMAQQVQELQPYKVLQLEQLARIRALERELLHMRVEHTQLLHRVKRRFLEDKAAFEREARQRVQSLARRAEREAVRALVAHTQAIKADNGRLRQELLLLLRRTQLLHHTRRQLLEQREQLHREHEDTRDLARVHGWLRRGPGGPPLWERPAFSQPTSRPGSLAAPISPSRAASQTPSVVPSRAAPRASSVVPSREASRVPSLVLSSMDSRVPSLATSKVGSRMPSLTASRAGSRALSLVQSLEGSGISSGSSPRVSSQDTLRSTKSGPKLLSGLSRDRDPALLPPQSEDSVNAEAAAEASPGRA", "length": 439 }, "evidence": [ { "id": "G3MXG2", "url": "https://omabrowser.org/oma/group/G3MXG2/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "S4R181-1", "protein_name": "Coiled-coil domain containing 166", "gene_name": "Ccdc166", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MAPKKKRGQNAGRKQETTEQPLSERAQYLQREYALLSESLVACEQRIDEVLQDNEFLNREAQRLREENRLYVGYVSAHALRCANAVVRVEDQNRMDLAQIRWQRAELASFYHGREDGVRAQLQEMKKRAENMTQRVQELQPYKELQLEQLARIRTLERELLHMRVEHTQLLHGVKRRFLDEKTAFEREARLQVQSLTRRSEREAARSLISHAQALKADNGYLRQELMRLLQRTQLLQDMRQQLLEQREQLRREHVDLKNLEQMHGWLQRGPGGPPLWQPPQSLQPSLRIGSTSHVLKAQATPQSVPTSRGQSMDLSHRPSKTPSILSSESLPGLSQKAGSVIALRSPSHPGSRVSSLTPSRKDSRVSSATPSRKGSRVPSMTSGTLRSREGSRISPQPSLREVSPEIDTPAKSSSKLPTALLEDQAPLSPQLEEAENAEDDTETVLEQA", "length": 449 }, "evidence": [ { "id": "G3MXG2", "url": "https://omabrowser.org/oma/group/G3MXG2/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" } ], "go_annotation": {}, "pro_annotation": [], "site_annotation": [ { "start_pos": 300, "end_pos": 302, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [ { "pdb_id": "AF-G3MXG2-F1", "pdb_chain": "global", "start_pos": 1, "end_pos": 449, 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"publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ], "tool_support": { "graph_view": "yes" } }, { "uniprot_canonical_ac": "G3MXH3-1", "uniprot_ac": "G3MXH3", "uniprot_id": "G3MXH3_BOVIN", "mass": { "chemical_mass": 10097.0, "monoisotopic_mass": 10097.0 }, "refseq": {}, "gene_names": [ { "name": "C11H2orf15", "type": "recommended", "evidence": [ { "id": "G3MXH3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3MXH3" } ] } ], "protein_names": [ { "name": "Chromosome 11 C2orf15 homolog", "type": "synonym", "evidence": [ { "id": "G3MXH3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3MXH3/entry#names_and_taxonomy" } ] } ], "function": [], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Bos taurus", "taxid": 9913, "evidence": [ { "database": "UniProtKB", "id": "G3MXH3", "url": "https://www.uniprot.org/uniprotkb/G3MXH3" } ], "common_name": 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The olfactory receptor proteins are members of a large family of G-protein-coupled receptors (GPCR) arising from single coding-exon genes. Olfactory receptors share a 7-transmembrane domain structure with many neurotransmitter and hormone receptors and are responsible for the recognition and G protein-mediated transduction of odorant signals. The olfactory receptor gene family is the largest in the genome. [provided by RefSeq, Jul 2008].", "evidence": [ { "database": "RefSeq", "id": "NP_001377585", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001377585" } ] }, { "annotation": "Putative odorant or sperm cell receptor.", "evidence": [ { "database": "UniProtKB", "id": "G3MXH6", "url": "https://www.uniprot.org/uniprotkb/G3MXH6#function" }, { "database": "UniProtKB", "id": "ARBA00003929", "url": "https://www.uniprot.org/uniprotkb/ARBA00003929#function" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Bos taurus", "taxid": 9913, "evidence": [ { "database": "UniProtKB", "id": "G3MXH6", "url": "https://www.uniprot.org/uniprotkb/G3MXH6" } ], "common_name": "Bovine", "glygen_name": "Bovine", "reference_species": "Bos taurus [9913]" } ], "gene": [ { "name": "OR7A88", "url": "https://www.uniprot.org/uniprotkb/G3MXH6", "locus": { "chromosome": "7", "start_pos": 10023816, "end_pos": 10022869, "strand": "-", "evidence": 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"database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR10656", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR10656", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR10656:SF9", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR10656:SF9", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF20266", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF20266", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "XP_005224834", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_005224834", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "G3MXK1", "url": "https://www.uniprot.org/uniprotkb/G3MXK1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "G3MXK1-1", "url": "https://www.uniprot.org/uniprotkb/G3MXK1-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MSVHYTLNLRVFWPLVTGLCTALVCLYHVLRGNAGARTEPPDGADGGFPLLKVAVLLLLGYILLRCRHAVRQRFLPGPPRMGGHSTFSAKHFPEPSLDILLESYYEHEVRLSPHVLGHSKAHVSRIVGELVRAGRARGSPGPIPGGALALAFRGDFIQVGSAYEQHKIRRPDGFDVLVPLRLPPLVALEPRSLGSEPELAPAFHGCFVCALKAPPGASGGHWLRDCKPFSDGFCVDVRGRRLLSATLVLRWFQAHLQRSLATVRYSLEGRCRVSLTPGGLEQPPTLHILPCRTDYGCCRLSMAVRLIPAVHLGDSVFLVAPPPPPSPAGPLSELPEGLRADALWGLNTARQEQKLLSWLQERAPPGACYLKCLQLLKALRDLGARGLDPTAAAQWGRILSSYVLKSALLAVLQREGAPAPGWDEAHLGDRLEELVQFLRDCLLRRRTLFHCVLGPGGAATEVGPLPKVLREAAPVDLLAAFDRQVRELAAARLLSTWRRLPQLLRAYGGPRYLVRCPPPRSQRTQGFPEDEP", "length": 532, "header": "tr|G3MXK1-1|G3MXK1_BOVIN Isoform 1 of ITPRIP like 2 OS=Bos taurus OX=9913 GN=ITPRIPL2 PE=3 SV=1 CANONICAL=G3MXK1-1" }, "isoforms": [ { "isoform_ac": "G3MXK1-1", "url": "https://www.uniprot.org/uniprotkb/G3MXK1/entry", "sequence": { "sequence": "MSVHYTLNLRVFWPLVTGLCTALVCLYHVLRGNAGARTEPPDGADGGFPLLKVAVLLLLGYILLRCRHAVRQRFLPGPPRMGGHSTFSAKHFPEPSLDILLESYYEHEVRLSPHVLGHSKAHVSRIVGELVRAGRARGSPGPIPGGALALAFRGDFIQVGSAYEQHKIRRPDGFDVLVPLRLPPLVALEPRSLGSEPELAPAFHGCFVCALKAPPGASGGHWLRDCKPFSDGFCVDVRGRRLLSATLVLRWFQAHLQRSLATVRYSLEGRCRVSLTPGGLEQPPTLHILPCRTDYGCCRLSMAVRLIPAVHLGDSVFLVAPPPPPSPAGPLSELPEGLRADALWGLNTARQEQKLLSWLQERAPPGACYLKCLQLLKALRDLGARGLDPTAAAQWGRILSSYVLKSALLAVLQREGAPAPGWDEAHLGDRLEELVQFLRDCLLRRRTLFHCVLGPGGAATEVGPLPKVLREAAPVDLLAAFDRQVRELAAARLLSTWRRLPQLLRAYGGPRYLVRCPPPRSQRTQGFPEDEP", "length": 532, "header": "tr|G3MXK1-1|G3MXK1_BOVIN Isoform 1 of ITPRIP like 2 OS=Bos taurus OX=9913 GN=ITPRIPL2 PE=3 SV=1 CANONICAL=G3MXK1-1" }, "locus": { "chromosome": "25", "start_pos": 16860268, "end_pos": 16858476, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000097620.1", "url": "https://www.ensembl.org/id/ENSBTAT00000097620.1" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000095639.1", "url": "https://www.ensembl.org/id/ENSBTAP00000095639.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [ { "id": "bta:783291", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?bta:783291", "resource": "KEGG Pathway" } ], "orthologs": [ { "uniprot_canonical_ac": "A0A287BGA3-1", "protein_name": "ITPRIP like 2", "gene_name": "ITPRIPL2", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MSVHYTLNLRVFWPLVTGLCTALVCLYHVLRGSGGARAEPPDSADGGFPLLKVAVLLLLGYILLRCRHAVRQRFLPGSPRLGGHSAFSPGHFGEPSLDILLESYYEHEVRLSPHVLGHSKAHVSRIVGELVRAGRARGSPGPIPGGALALAFRGDFIQVGSAYEQHKIRRPDSFDVLVPLRLPPLVALEPRSLGAEPELAPAVHGCFVCALKAPPGASGGQWLRDCKPFADGFCVDVRGRRHLSATLVLRWFQSHLQRSLATVRYSLEGRCRVTLTPGSLEQPPTLHILPCRTDYGCCRLSMAVRLIPAVHLGDNVFLVAPPPPPSPVGPISELPGGLRADALWGVNTARQEQKLLSWLQERAPPGACYLKCLQLLKALRDLGARGLDPTAAIQWGRILSSYVLKTVLLAVLLREGVPARAWDEVHLGERLEELVKFLRDCLLRRRTLFHCVLGPGGAAAEVGPLPKVLREAAPVDLLAAFDRHAREVAAARLLSTWRRLPQLLRAYGGPRYLARCPPPRSQRTQGFPEDEP", "length": 532 }, "evidence": [ { "id": "G3MXK1", "url": "https://omabrowser.org/oma/group/G3MXK1/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "Q3MIP1-1", "protein_name": "Inositol 1,4,5-trisphosphate receptor-interacting protein-like 2", "gene_name": "ITPRIPL2", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MSVHYTLNLRVFWPLVTGLCTALVCLYHVLRGSGGARAEPADGVDGGFPLLKVAVLLLLSYVLLRCRHAVRQRFLPGSPRLEGHAAFSSRHFREPGLSILLESYYEHEVRLSPHVLGHSKAHVSRIVGELVRAGRARGSPGLIPGGALALAFRGDFIQVGSAYEQHKIRRPDSFDVLVPLRLPPLVALEPRSLGEEPALAPAFRGCFLCALKAPPSPSGASGGHWLRDCKPFADAFCVDVRGRRHLSATLVLRWFQSHLQRSLATVRYSLEGRCRVTLTPGGLEQPPTLHILPCRTDYGCCRLSMAVRLIPAVHLGDGVFLVAPPPPPLPSAPLLELPEGLRAEALWGVNTARQEQKLLSWLQERAAPGACYLKCLQLLKALRDLGARGLDSAAATQWGRILSSYVLKTVLLAVLLRKGAPGQGWDEEHLGRCLEELVQFLRDCLLRRHTLFHCVLGPGGAAAEVGPLPKALREAAPVDLLAAFDGHARELAAARLLSTWQRLPQLLRAYGGPRYLARCPPPRSQRTQGFLEGEP", "length": 535 }, "evidence": [ { "id": "G3MXK1", "url": "https://omabrowser.org/oma/group/G3MXK1/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "Q3UV16-1", "protein_name": "Inositol 1,4,5-trisphosphate receptor-interacting protein-like 2", "gene_name": "Itpripl2", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MSVRYTLNLRVFWPLVTGLCTALVCLYHALRSSEDARAESPDGADSGFPLLKVAILLLLGYILLRCRHAIRQRLLPGSSRPRGHANFSARSLQEPGLSILLESYYEHEVRLSPHVLGHSKAHVSRIVGELVQAGRARGSPGLITGGALALAFRGDFIQVGSAYEQHKIRRPDSFDVLVPLRLPPQVALEPRSLGTEPSLTPAFRSCFVCALKAPPSPSGASTGQWHRDCKPFAEGFCVDVQGRRHLSATLVLRWFQAHLQRSLATVRYSLEGRCRVSLTPGSLEQPPTLHILPCRTDYGCCRLSMAVRLIPAVHLGDGVFLVAPPPPPSPSGALSELPGGLRAEALWGVNTARQEQKLLGWLQERAPPGACYLKCLQLLKALRDLGARGLDPMAATHWGRILSSYVLKTAVLEVLLNEGSPTPSWDEAHLSECLEKLVKFLRDCLLRRRDLFHCVLGPTGAAAEVGPLPKVLREAAPVDLLAPFDPHSRELAAARLLSTWRRLPQLLRVYGGPRYLARCPAPRSQRIQGSPEDEP", "length": 535 }, "evidence": [ { "id": "G3MXK1", "url": "https://omabrowser.org/oma/group/G3MXK1/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" } ], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 1, "go_terms": [ { "name": "membrane", "id": "GO:0016020", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016020", "evidence": [ { "database": "UniProtKB", "id": "G3MXK1", "url": "https://www.uniprot.org/uniprotkb/G3MXK1" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "G3MXK1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3MXK1" }, { "id": "PF20266", "database": "Pfam", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF20266" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "Mab-21-like HhH/H2TH-like", "eco_id": "ECO_0000259", "start_pos": 369, "end_pos": 449, "start_aa": "Tyr", "end_aa": "Phe", "glycosite_overlap": [] } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "homologset.oma", "label": "OMA Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ], "tool_support": { "graph_view": "yes" } }, { "uniprot_canonical_ac": "G3MXL5-1", "uniprot_ac": "G3MXL5", "uniprot_id": "G3MXL5_BOVIN", "mass": { "chemical_mass": 44098.0, "monoisotopic_mass": 44098.0 }, "refseq": { "ac": "XP_010817545", "name": "zinc finger protein 75A isoform X1", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_010817545" }, "gene_names": [ { "name": "LOC104970105", "type": "recommended", "evidence": [ { "id": "G3MXL5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3MXL5" } ] }, { "name": "LOC104970105", "type": "synonym", "evidence": [ { "id": "XP_010817545", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_010817545" } ] } ], "protein_names": [ { "name": "Zinc finger protein 75A", "type": "recommended", "evidence": [ { "id": "G3MXL5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3MXL5/entry#names_and_taxonomy" } ] }, { "name": "zinc finger protein 75A isoform X1", "type": "synonym", "evidence": [ { "id": "XP_010817545", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_010817545" } ] } ], "function": [ { "annotation": "May be involved in transcriptional regulation.", "evidence": [ { "database": "UniProtKB", "id": "G3MXL5", "url": "https://www.uniprot.org/uniprotkb/G3MXL5#function" }, { "database": "UniProtKB", "id": "ARBA00003767", "url": "https://www.uniprot.org/uniprotkb/ARBA00003767#function" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Bos taurus", "taxid": 9913, "evidence": [ { "database": "UniProtKB", "id": "G3MXL5", "url": "https://www.uniprot.org/uniprotkb/G3MXL5" } ], "common_name": "Bovine", "glygen_name": "Bovine", "reference_species": "Bos taurus [9913]" } ], "gene": [ { "name": "LOC104970105", "url": "https://www.uniprot.org/uniprotkb/G3MXL5", "locus": {} } ], "crossref": [ { "id": "G3MXL5", "url": "https://alphafold.ebi.ac.uk/entry/G3MXL5", "database": "AlphaFoldDB", "categories": [] }, { "id": "ENSBTAG00000045912", "url": "https://bgee.org/?page=gene&gene_id=ENSBTAG00000045912", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "cd07765", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd07765", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "104970105", "url": "https://www.ncbi.nlm.nih.gov/gene/104970105", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR001909", "url": "https://www.ebi.ac.uk/interpro/entry/IPR001909", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR013087", "url": "https://www.ebi.ac.uk/interpro/entry/IPR013087", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR036051", "url": "https://www.ebi.ac.uk/interpro/entry/IPR036051", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR036236", "url": "https://www.ebi.ac.uk/interpro/entry/IPR036236", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "bta:104970105", "url": "https://www.genome.jp/dbget-bin/www_bget?bta:104970105", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "PTHR24381", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR24381", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR24381:SF390", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR24381:SF390", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00096", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00096", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF01352", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF01352", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "R-BTA-212436", "url": "https://www.reactome.org/PathwayBrowser/#R-BTA-212436", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "XP_010817545", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_010817545", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "G3MXL5", "url": "https://www.uniprot.org/uniprotkb/G3MXL5", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "G3MXL5-1", "url": "https://www.uniprot.org/uniprotkb/G3MXL5-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MMTVDLKVAVQELGKEAVLLGEAAEAPGFQLKPAESQPVGMSLEEEVWNIHQGLQEPLSRNTHKEPEPVCERVVPTYQILALPEETNTKDWTVAPEFILPESQGLLTFEEVAIYFSQEEWELLNPTQKALYNDVMHENYETVISLALFVLPKPKVIYLEQGEEPYIQGSPMFKDNPGELLSEIKLKNDMENHQLMCLSDLEIQAPGDIVSKKASVNVHQKTTGKENHGDVHRLGKWHQDFPVKERNKLSNWWEEELLKLMELHKKERATEKPFKCQECGKSFRVSSDLIKHQRIHTEEKPYKCQQCDKRFRWRSDLNKHLTTHQGVKPYKCSWCGKSFSQNSHLHTHQRIHTGEKPFTCHECGKKFSQNSHLIKHRRTHL", "length": 380, "header": "tr|G3MXL5-1|G3MXL5_BOVIN Isoform 1 of Zinc finger protein 75A OS=Bos taurus OX=9913 GN=LOC104970105 PE=3 SV=3 CANONICAL=G3MXL5-1" }, "isoforms": [ { "isoform_ac": "G3MXL5-1", "url": "https://www.uniprot.org/uniprotkb/G3MXL5/entry", "sequence": { "sequence": "MMTVDLKVAVQELGKEAVLLGEAAEAPGFQLKPAESQPVGMSLEEEVWNIHQGLQEPLSRNTHKEPEPVCERVVPTYQILALPEETNTKDWTVAPEFILPESQGLLTFEEVAIYFSQEEWELLNPTQKALYNDVMHENYETVISLALFVLPKPKVIYLEQGEEPYIQGSPMFKDNPGELLSEIKLKNDMENHQLMCLSDLEIQAPGDIVSKKASVNVHQKTTGKENHGDVHRLGKWHQDFPVKERNKLSNWWEEELLKLMELHKKERATEKPFKCQECGKSFRVSSDLIKHQRIHTEEKPYKCQQCDKRFRWRSDLNKHLTTHQGVKPYKCSWCGKSFSQNSHLHTHQRIHTGEKPFTCHECGKKFSQNSHLIKHRRTHL", "length": 380, "header": "tr|G3MXL5-1|G3MXL5_BOVIN Isoform 1 of Zinc finger protein 75A OS=Bos taurus OX=9913 GN=LOC104970105 PE=3 SV=3 CANONICAL=G3MXL5-1" }, "locus": { "chromosome": "25", "start_pos": 2783308, "end_pos": 2777505, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000063864.4", "url": "https://www.ensembl.org/id/ENSBTAT00000063864.4" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000054282.3", "url": "https://www.ensembl.org/id/ENSBTAP00000054282.3" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [ { "id": "bta:104970105", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?bta:104970105", "resource": "KEGG Pathway" }, { "id": "R-BTA-212436", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-BTA-212436", "resource": "Reactome", "description": "Generic Transcription Pathway" } ], "orthologs": [], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 1, "go_terms": [ { "name": "nucleus", "id": "GO:0005634", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005634", "evidence": [ { "database": "UniProtKB", "id": "G3MXL5", "url": "https://www.uniprot.org/uniprotkb/G3MXL5" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 2, "go_terms": [ { "name": "DNA-templated transcription", "id": "GO:0006351", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006351", "evidence": [ { "database": "UniProtKB", "id": "G3MXL5", "url": "https://www.uniprot.org/uniprotkb/G3MXL5" } ], "pmid": "" }, { "name": "regulation of transcription by 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"id": "G3MXL5", "url": "https://www.uniprot.org/uniprotkb/G3MXL5" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [ { "pdb_id": "AF-G3MXL5-F1", "pdb_chain": "global", "start_pos": 1, "end_pos": 380, "overlap": "1.0", "method": "AlphaFold", "type": "alphafold", "resolution": -1.0, "url": "https://data.glygen.org/ln2downloads/pdb/current/AF-G3MXL5-F1.pdb", "url_external": "https://alphafold.ebi.ac.uk/entry/G3MXL5" } ], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "G3MXL5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3MXL5" }, { "id": "PS50157", "database": "PROSITE", "url": "https://prosite.expasy.org/PS50157" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "C2H2-type", "eco_id": "ECO_0000259", "start_pos": 273, "end_pos": 300, "start_aa": "Phe", "end_aa": "Pro", 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Subunit A is transcriptionally active and its transcription activity is strongly enhanced by binding to the dimeric complex of the SIII regulatory subunits B and C (elongin BC complex). 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], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "Q9CWP9-1", "protein_name": "Proline-rich protein 23A3", "gene_name": "Prr23a3", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MLRTRPRSPSADPAPCWSPQTPAPSPAKRRRLHQEPACPEPLAQPELEAPAEPTTSVVFLAAGSALQLPLDGVDLLLEPEPTSVLQVSLQGHTILLVPEGLQDSTHFGQPGFVAISPQGAAAQDGPQDHLVGLQEETFCEYFYQEDVCDEDADLEFLEHWASPPDDQANGNFSSIPGVPSPLSQDQVPGPSTGAEQYSPRFIWELDINMLGPFPGSPLQPLPPSPSRNPQEQLPPCPPCSPRAPRRARKRLVYE", "length": 254 }, "evidence": [ { "id": "G3MXP0", "url": "https://omabrowser.org/oma/group/G3MXP0/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" } ], "go_annotation": {}, "pro_annotation": [], "site_annotation": [ { "start_pos": 50, "end_pos": 52, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [ { "pdb_id": "AF-G3MXP0-F1", "pdb_chain": 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"https://bgee.org/?page=gene&gene_id=ENSBTAG00000000560", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "IPR002136", "url": "https://www.ebi.ac.uk/interpro/entry/IPR002136", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR023574", "url": "https://www.ebi.ac.uk/interpro/entry/IPR023574", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR025755", "url": "https://www.ebi.ac.uk/interpro/entry/IPR025755", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR045240", "url": "https://www.ebi.ac.uk/interpro/entry/IPR045240", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "PTHR19431", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR19431", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00573", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00573", "database": "Pfam", "categories": [ "Protein 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"database": "Ensembl Peptide", "id": "ENSBTAP00000054334.4", "url": "https://www.ensembl.org/id/ENSBTAP00000054334.4" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [], "orthologs": [], "go_annotation": { "categories": [ { "name": "Molecular Function", "total": 2, "go_terms": [ { "name": "RNA binding", "id": "GO:0003723", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003723", "evidence": [ { "database": "UniProtKB", "id": "G3MXR5", "url": "https://www.uniprot.org/uniprotkb/G3MXR5" } ], "pmid": "" }, { "name": "structural constituent of ribosome", "id": "GO:0003735", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003735", "evidence": [ { "database": "UniProtKB", "id": "G3MXR5", "url": "https://www.uniprot.org/uniprotkb/G3MXR5" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 1, "go_terms": [ { "name": "translation", "id": "GO:0006412", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006412", "evidence": [ { "database": "UniProtKB", "id": "G3MXR5", "url": "https://www.uniprot.org/uniprotkb/G3MXR5" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 1, "go_terms": [ { "name": "cytosolic large ribosomal subunit", "id": "GO:0022625", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0022625", "evidence": [ { "database": "UniProtKB", "id": "G3MXR5", "url": "https://www.uniprot.org/uniprotkb/G3MXR5" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 116, "end_pos": 118, "annotation": "n_glycosylation_sequon" }, { "start_pos": 21, "end_pos": 23, "annotation": "n_glycosylation_sequon" }, { "start_pos": 231, "end_pos": 233, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [ { "pdb_id": "AF-G3MXR5-F1", "pdb_chain": "global", "start_pos": 1, "end_pos": 422, "overlap": "1.0", "method": "AlphaFold", "type": 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"start_pos": 231, "end_pos": 233 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { 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The olfactory receptor proteins are members of a large family of G-protein-coupled receptors (GPCR) arising from single coding-exon genes. Olfactory receptors share a 7-transmembrane domain structure with many neurotransmitter and hormone receptors and are responsible for the recognition and G protein-mediated transduction of odorant signals. The olfactory receptor gene family is the largest in the genome. [provided by RefSeq, Jul 2008].", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001377410" }, "gene_names": [ { "name": "OR5F2C", "type": "recommended", "evidence": [ { "id": "G3MXT1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3MXT1" } ] }, { "name": "OR5F2C", "type": "synonym", "evidence": [ { "id": "NP_001377410", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001377410" } ] } ], "protein_names": [ { "name": "Olfactory receptor family 5 subfamily F member 2C", "type": "synonym", "evidence": [ { "id": "G3MXT1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3MXT1/entry#names_and_taxonomy" } ] }, { "name": "olfactory receptor 5F1", "type": "synonym", "evidence": [ { "id": "NP_001377410", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001377410" } ] }, { "name": "olfactory receptor family 5 subfamily F member 2C", "type": "synonym", "evidence": [ { "id": "NP_001377410", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001377410" } ] } ], "function": [ { "annotation": "Olfactory receptors interact with odorant molecules in the nose, to initiate a neuronal response that triggers the perception of a smell. The olfactory receptor proteins are members of a large family of G-protein-coupled receptors (GPCR) arising from single coding-exon genes. Olfactory receptors share a 7-transmembrane domain structure with many neurotransmitter and hormone receptors and are responsible for the recognition and G protein-mediated transduction of odorant signals. The olfactory receptor gene family is the largest in the genome. [provided by RefSeq, Jul 2008].", "evidence": [ { "database": "RefSeq", "id": "NP_001377410", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001377410" } ] }, { "annotation": "Putative odorant or sperm cell receptor.", "evidence": [ { "database": "UniProtKB", "id": "G3MXT1", "url": "https://www.uniprot.org/uniprotkb/G3MXT1#function" }, { "database": "UniProtKB", "id": "ARBA00003929", "url": "https://www.uniprot.org/uniprotkb/ARBA00003929#function" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Bos taurus", "taxid": 9913, "evidence": [ { "database": "UniProtKB", "id": "G3MXT1", "url": "https://www.uniprot.org/uniprotkb/G3MXT1" } ], "common_name": "Bovine", "glygen_name": "Bovine", "reference_species": "Bos taurus [9913]" } ], "gene": [ { "name": "OR5F2C", "url": "https://www.uniprot.org/uniprotkb/G3MXT1", "locus": { "chromosome": "15", "start_pos": 78668335, "end_pos": 78669279, "strand": "+", "evidence": 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"id": "G3MXT1-1", "url": "https://www.uniprot.org/uniprotkb/G3MXT1-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MARKNYTLLTEFILLGLADSLELQITLFCLFSVIYTLTVVGNVGMILLIRADSRLHTPMYFFLANLSFVDVCYSSTITPKMLVDLLSEKKSISFAGCFLQMYFFLPLATTECILFGLMAHDRYVAICNPLLYSLIMSRTVCLKMAAGAFTAGLLNSMVLTSCISSFNFCSSIVIHHFFCDSPPLFKLSCSDTHLYESILSIFAGVNIAGSLLVILTSYCYILFSIFHMHAGEGRRKAFSTCASHLTAIILFYSTSIYTYLRPTSSYSLTQDKVASVFYTVVIPMLNPLIYSLRNREVKKALWNVVTRKRISSFL", "length": 314, "header": "tr|G3MXT1-1|G3MXT1_BOVIN Isoform 1 of Olfactory receptor family 5 subfamily F member 2C OS=Bos taurus OX=9913 GN=OR5F2C PE=3 SV=2 CANONICAL=G3MXT1-1" }, "isoforms": [ { "isoform_ac": "G3MXT1-1", "url": "https://www.uniprot.org/uniprotkb/G3MXT1/entry", "sequence": { "sequence": 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phosphatase 2 OS=Bos taurus OX=9913 GN=SGPP2 PE=3 SV=2 CANONICAL=G3MXX9-1" }, "isoforms": [ { "isoform_ac": "G3MXX9-1", "url": "https://www.uniprot.org/uniprotkb/G3MXX9/entry", "sequence": { "sequence": "MAELLWSLQDSQLVARFQRRCGLFPALDEGPGENGAGPADGEAQTPELGHLPAAKGKGAGEPANGLRRLAAPQAYVQKYVVKNYFYYYLFRFSAALGQEVFYITFLPFTHWNIDPYLSRRLTIIWVLVMYIGQVTKEILKWPRPFSPPVVKLEKRVMAEYGMPSTHAMAATAISFTLLISTMDRYQYPFVLGLMMAVVFSTLVGLSRLYTGMHTVLDVLGGILITAILIVLTYPAWTLIDRLDSASPLLPVCVLVVPFFLCYNYPVSDYYSPTRADTTTIMAAGAGVTIGFWINHFFQLVSEPMESLPVIQNIPPLTTDLLVLGLAKFTVGIVLILLVRQLVQKLSLQVLYSWFKVVTRNKEARRRLEIEVPYKFVTYTSVGICAITFVPMLHRFLGLL", "length": 399, "header": "tr|G3MXX9-1|G3MXX9_BOVIN Isoform 1 of Sphingosine-1-phosphate phosphatase 2 OS=Bos taurus OX=9913 GN=SGPP2 PE=3 SV=2 CANONICAL=G3MXX9-1" }, "locus": { "chromosome": "2", "start_pos": 110734609, "end_pos": 110589763, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000064756.4", "url": "https://www.ensembl.org/id/ENSBTAT00000064756.4" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000054401.2", "url": "https://www.ensembl.org/id/ENSBTAP00000054401.2" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [ { "id": "bta:100337041", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?bta:100337041", "resource": "KEGG Pathway" }, { "id": "R-BTA-9845614", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-BTA-9845614", "resource": "Reactome", "description": "Sphingolipid catabolism" } ], "orthologs": [], "go_annotation": { "categories": [ { "name": "Biological Process", "total": 3, "go_terms": [ { "name": "sphingosine metabolic process", "id": "GO:0006670", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006670", "evidence": [ { "database": "UniProtKB", "id": "G3MXX9", "url": "https://www.uniprot.org/uniprotkb/G3MXX9" } ], "pmid": "" }, { "name": "regulation of type B pancreatic cell proliferation", "id": "GO:0061469", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0061469", "evidence": [ { "database": "UniProtKB", "id": "G3MXX9", "url": "https://www.uniprot.org/uniprotkb/G3MXX9" } ], "pmid": "" }, { "name": "phospholipid dephosphorylation", "id": "GO:0046839", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0046839", "evidence": [ { "database": "UniProtKB", "id": "G3MXX9", "url": "https://www.uniprot.org/uniprotkb/G3MXX9" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 1, "go_terms": [ { "name": "endoplasmic reticulum membrane", "id": "GO:0005789", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005789", "evidence": [ { "database": "UniProtKB", "id": "G3MXX9", "url": "https://www.uniprot.org/uniprotkb/G3MXX9" } ], "pmid": "" } ] }, { "name": "Molecular Function", "total": 1, "go_terms": [ { "name": "sphingosine-1-phosphate phosphatase activity", "id": "GO:0042392", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0042392", "evidence": [ { "database": "UniProtKB", "id": "G3MXX9", "url": "https://www.uniprot.org/uniprotkb/G3MXX9" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [], "ptm_annotation": [], "interactions": [], "reactions": [ { "id": "27514", "name": "", "equation": "sphinganine 1-phosphate + H2O = sphinganine + phosphate", "summary": "", "cellular_location": "", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [], "evidence": [ { "id": "27514", "database": "Rhea", "url": "https://www.rhea-db.org/rhea/27514" } ] }, { "id": "27518", "name": "", "equation": "sphing-4-enine 1-phosphate + H2O = sphing-4-enine + phosphate", "summary": "", "cellular_location": "", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [ "A0AAA9STE8-1", "Q3SZE3-1", "Q2HJ61-1" ], "evidence": [ { "id": "27518", "database": "Rhea", "url": "https://www.rhea-db.org/rhea/27518" } ] } ], "reaction_participants": [], "reaction_enzymes": [ { "uniprot_ac": "A0AAA9STE8", "gene_name": "PLPP1", "activity": [ { "ec_number": "3.1.3.4", "activity": "1-O-alkyl-2-acyl-sn-glycero-3-phosphate + H2O = 1-O-alkyl-2-acyl-sn-glycerol + phosphate.", "evidence": [ { "id": "A0AAA9STE8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9STE8" } ] }, { "ec_number": "3.1.3.106", "activity": "a 1-acyl-sn-glycero-3-phosphate + H2O = a 1-acyl-sn-glycerol + phosphate.", "evidence": [ { "id": "A0AAA9STE8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9STE8" } ] }, { "ec_number": "3.6.1.75", "activity": "a 1,2-diacyl-sn-glycerol 3-diphosphate + H2O = a 1,2-diacyl-sn-glycero-3-phosphate + phosphate + H(+).", "evidence": [ { "id": "A0AAA9STE8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9STE8" } ] }, { "ec_number": "3.6.1.75", "activity": "", "evidence": [ { "id": "A0AAA9STE8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9STE8" } ] }, { "ec_number": "3.1.3.4", "activity": "", "evidence": [ { "id": "A0AAA9STE8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9STE8" } ] }, { "ec_number": "3.1.3.106", "activity": "", "evidence": [ { "id": "A0AAA9STE8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9STE8" } ] } ] }, { "uniprot_ac": "Q2HJ61", "gene_name": "PLPP2", "activity": [ { "ec_number": "3.1.3.-", "activity": "", "evidence": [ { "id": "Q2HJ61", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q2HJ61" } ] }, { "ec_number": "3.1.3.4", "activity": "1-O-alkyl-2-acyl-sn-glycero-3-phosphate + H2O = 1-O-alkyl-2-acyl-sn-glycerol + phosphate.", "evidence": [ { "id": "Q2HJ61", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q2HJ61" } ] }, { "ec_number": "3.1.3.4", "activity": "", "evidence": [ { "id": "Q2HJ61", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q2HJ61" } ] } ] }, { "uniprot_ac": "Q3SZE3", "gene_name": "PLPP3", "activity": [ { "ec_number": "3.1.3.-", "activity": "", "evidence": [ { "id": "Q3SZE3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q3SZE3" } ] }, { "ec_number": "3.1.3.4", "activity": "1-O-alkyl-2-acyl-sn-glycero-3-phosphate + H2O = 1-O-alkyl-2-acyl-sn-glycerol + phosphate.", "evidence": [ { "id": "Q3SZE3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q3SZE3" } ] }, { "ec_number": "3.1.3.4", "activity": "", "evidence": [ { "id": "Q3SZE3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q3SZE3" } ] } ] } ], "biomarkers": [], "structures": [ { "pdb_id": "AF-G3MXX9-F1", "pdb_chain": "global", "start_pos": 1, "end_pos": 399, "overlap": "1.0", "method": "AlphaFold", "type": "alphafold", "resolution": -1.0, "url": "https://data.glygen.org/ln2downloads/pdb/current/AF-G3MXX9-F1.pdb", "url_external": "https://alphafold.ebi.ac.uk/entry/G3MXX9" } ], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "G3MXX9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3MXX9" }, { "id": "SM00014", "database": "SMART", "url": "http://smart.embl.de/smart/do_annotation.pl?DOMAIN=SM00014" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "Phosphatidic acid phosphatase type 2/haloperoxidase", "eco_id": "ECO_0000259", "start_pos": 119, "end_pos": 233, "start_aa": "Arg", "end_aa": "Tyr", "glycosite_overlap": [] } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ], "tool_support": { "graph_view": "yes" } }, { "uniprot_canonical_ac": "G3MXY1-1", "uniprot_ac": "G3MXY1", "uniprot_id": "G3MXY1_BOVIN", "mass": { "chemical_mass": 70277.0, "monoisotopic_mass": 70277.0 }, "refseq": { "ac": "XP_024834460", "name": "proline and serine-rich protein 3", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_024834460" }, "gene_names": [ { "name": "PROSER3", "type": "recommended", "evidence": [ { "id": "G3MXY1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3MXY1" } ] }, { "name": "PROSER3", "type": "synonym", "evidence": [ { "id": "XP_024834460", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_024834460" } ] } ], "protein_names": [ { "name": "Proline and serine rich 3", "type": "synonym", "evidence": [ { "id": "G3MXY1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3MXY1/entry#names_and_taxonomy" } ] }, { "name": "proline and serine-rich protein 3", "type": "synonym", "evidence": [ { "id": "XP_024834460", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_024834460" } ] } ], "function": [], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Bos taurus", "taxid": 9913, "evidence": [ { "database": "UniProtKB", "id": "G3MXY1", "url": "https://www.uniprot.org/uniprotkb/G3MXY1" } ], "common_name": "Bovine", "glygen_name": "Bovine", "reference_species": "Bos taurus [9913]" } ], "gene": [ { "name": "PROSER3", "url": "https://www.uniprot.org/uniprotkb/G3MXY1", "locus": { "chromosome": "18", "start_pos": 46481515, "end_pos": 46469776, "strand": "-", "evidence": [ { "database": "Ensembl Gene", "id": "ENSBTAG00000018599", "url": "https://www.ensembl.org/id/ENSBTAG00000018599" } ] } } ], "crossref": [ { "id": "G3MXY1", "url": "https://alphafold.ebi.ac.uk/entry/G3MXY1", "database": "AlphaFoldDB", "categories": [] }, { "id": "ENSBTAG00000018599", "url": "https://bgee.org/?page=gene&gene_id=ENSBTAG00000018599", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "785831", "url": "https://www.ncbi.nlm.nih.gov/gene/785831", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR037646", "url": "https://www.ebi.ac.uk/interpro/entry/IPR037646", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "bta:785831", "url": "https://www.genome.jp/dbget-bin/www_bget?bta:785831", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "SPPGFFW", "url": "https://omabrowser.org/oma/group/SPPGFFW/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "G3MXY1", "url": "https://www.orthodb.org/?gene=G3MXY1", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR22045", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR22045", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR22045:SF6", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR22045:SF6", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF27936", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF27936", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "XP_024834460", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_024834460", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0ABI0NZZ3", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NZZ3", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0ABI0NZZ3-1", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NZZ3-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "G3MXY1", "url": "https://www.uniprot.org/uniprotkb/G3MXY1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "G3MXY1-1", "url": "https://www.uniprot.org/uniprotkb/G3MXY1-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MGTLSPSRSQRSRLPEASKALATGPSSPELFEESWPSSSGTPSPPSTAEGQIRASPPPIVTDSGDSVVAKYINRFRQAQPTSREERQSAGPTPADFWWLRPESSDPGSQLAAGASEPEGRPNTAALTHAKMASASKAKAVAPLQEIKQSLNTWNSSLLDLETLSLQSRAARLLKRSKASVSSTSSLSPSDGGSSSFPISSDGLSPFSMTFTPDSIKDPDITAQATPAPAPIPTPAPSSSQAPLRPEDDILYQWRQRRKLEQARRSQGDGTWVLPQTPALTTSVPSPICPQPSPPAAETLGSLGTQSNSIPLWGSMVPPGLQEAFPMERPPIPPGFSPHIFWGPSPHGFFWAPQPSPWIPLGIIPPTLPASTPGPPASVPAPLASTPAPPASTPAPPASTPTTPAALQGPPTPAPSSPEELEKQSSKPRRSRAQLRESSGRVMAADEHEGPGPQLRGALGQVVKARLFPDCLEDTPPRLEGPPPHEAEPRKAKATHPLTPRSEVTAHLSESRDRSKAVSRNAKTMLPLAGSVPRKDKDTPLAEVKCLQPKILPPPAEVVATCVTAPRSPFEAGSLEVVATPSPAAGDAPSEDLLSQAARLLQAAEDSDGSEFQDDPILQVLRIQRTALRQQKRKVDAQIAHLLGHPEDPESWSSPARSPPPDPQGCG", "length": 666, "header": "tr|G3MXY1-1|G3MXY1_BOVIN Isoform 1 of Proline and serine rich 3 OS=Bos taurus OX=9913 GN=PROSER3 PE=4 SV=2 CANONICAL=G3MXY1-1" }, "isoforms": [ { "isoform_ac": "A0ABI0NZZ3-1", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NZZ3/entry", "sequence": { "sequence": "MGTLSPSRSQRSRLPEASKALATGPSSPELFEESWPSSSGTPSPPSTAEGQIRASPPPIVTDSGDSVVAKYINRFRQAQPTSREERQSAGPTPADFWWLRPESSDPGSQLAAGASEPEGRPNTAALTHAKMASASKAKAVAPLQEIKQSLNTWNSSLLDLETLSLQSRAARLLKRSKASVSSTSSLSPSDGGSSSFPISSDGLSPFSMTFTPDSIKDPDITAQATPAPAPIPTPAPSSSQAPLRPEDDILYQWRQRRKLEQARRSQGDGTWVLPQTPALTTSVPSPICPQPSPPAAETLGSLGTQSNSIPLWGSMVPPGLQEAFPMERPPIPPGFSPHIFWGPSPHGFFWAPQPSPWIPLGIIPPTLPASTPGPPASVPAPLASTPAPPASTPAPPASTPTTPAALQGPPTPAPSSPEELEKQSSKPRRSRAQLRESSGRVMAADEHEGPGPQLRGALGQVVKARLFPDCLEDTPPRLEGPPPHEAEPRKAKATHPLTPRSEVTAHLSESRDRSKAVSRNAKTMLPLAGSVPRKDKDTPLAEVKCLQPKILPPPAEVVATCVTAPRSPFEAGSLEVVATPSPAAGDAPSEDLLSQAARLLQAAEDSDGSEFQDDPILQVLRIQRTALRQQKR", "length": 632, "header": "tr|A0ABI0NZZ3-1|A0ABI0NZZ3_BOVIN Computationally mapped isoform of Proline and serine rich 3 OS=Bos taurus OX=9913 GN=PROSER3 PE=4 SV=1 CANONICAL=G3MXY1-1" }, "locus": { "chromosome": "18", "start_pos": 46481169, "end_pos": 46471499, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000137924.1", "url": "https://www.ensembl.org/id/ENSBTAT00000137924.1" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000106940.1", "url": "https://www.ensembl.org/id/ENSBTAP00000106940.1" } ] } }, { "isoform_ac": "G3MXY1-1", "url": "https://www.uniprot.org/uniprotkb/G3MXY1/entry", "sequence": { "sequence": "MGTLSPSRSQRSRLPEASKALATGPSSPELFEESWPSSSGTPSPPSTAEGQIRASPPPIVTDSGDSVVAKYINRFRQAQPTSREERQSAGPTPADFWWLRPESSDPGSQLAAGASEPEGRPNTAALTHAKMASASKAKAVAPLQEIKQSLNTWNSSLLDLETLSLQSRAARLLKRSKASVSSTSSLSPSDGGSSSFPISSDGLSPFSMTFTPDSIKDPDITAQATPAPAPIPTPAPSSSQAPLRPEDDILYQWRQRRKLEQARRSQGDGTWVLPQTPALTTSVPSPICPQPSPPAAETLGSLGTQSNSIPLWGSMVPPGLQEAFPMERPPIPPGFSPHIFWGPSPHGFFWAPQPSPWIPLGIIPPTLPASTPGPPASVPAPLASTPAPPASTPAPPASTPTTPAALQGPPTPAPSSPEELEKQSSKPRRSRAQLRESSGRVMAADEHEGPGPQLRGALGQVVKARLFPDCLEDTPPRLEGPPPHEAEPRKAKATHPLTPRSEVTAHLSESRDRSKAVSRNAKTMLPLAGSVPRKDKDTPLAEVKCLQPKILPPPAEVVATCVTAPRSPFEAGSLEVVATPSPAAGDAPSEDLLSQAARLLQAAEDSDGSEFQDDPILQVLRIQRTALRQQKRKVDAQIAHLLGHPEDPESWSSPARSPPPDPQGCG", "length": 666, "header": "tr|G3MXY1-1|G3MXY1_BOVIN Isoform 1 of Proline and serine rich 3 OS=Bos taurus OX=9913 GN=PROSER3 PE=4 SV=2 CANONICAL=G3MXY1-1" }, "locus": { "chromosome": "18", "start_pos": 46481426, "end_pos": 46471499, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000064272.4", "url": "https://www.ensembl.org/id/ENSBTAT00000064272.4" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000054404.2", "url": "https://www.ensembl.org/id/ENSBTAP00000054404.2" } ] } } ], "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "other", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 225, "start_aa": "Thr", "end_pos": 225, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr225", "evidence": [ { "id": "", "database": "GlyGen", "url": "https://data.glygen.org/" } ], "filter_code": "000000000000000010000.00000000001000.0.01000" }, { "glytoucan_ac": "", "type": "O-linked", "subtype": "other", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 233, "start_aa": "Thr", "end_pos": 233, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr233", "evidence": [ { "id": "", "database": "GlyGen", "url": "https://data.glygen.org/" } ], "filter_code": "000000000000000010000.00000000001000.0.01000" }, { "glytoucan_ac": "", "type": "O-linked", "subtype": "other", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 385, "start_aa": "Thr", "end_pos": 385, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr385", "evidence": [ { "id": "", "database": "GlyGen", "url": "https://data.glygen.org/" } ], "filter_code": "000000000000000010000.00000000001000.0.01000" }, { "glytoucan_ac": "", "type": "O-linked", "subtype": "other", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 392, "start_aa": "Thr", "end_pos": 392, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr392", "evidence": [ { "id": "", "database": "GlyGen", "url": "https://data.glygen.org/" } ], "filter_code": "000000000000000010000.00000000001000.0.01000" }, { "glytoucan_ac": "", "type": "O-linked", "subtype": "other", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 411, "start_aa": "Thr", "end_pos": 411, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr411", "evidence": [ { "id": "", "database": "GlyGen", "url": "https://data.glygen.org/" } ], "filter_code": "000000000000000010000.00000000001000.0.01000" }, { "glytoucan_ac": "", "type": "O-linked", "subtype": "other", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 41, "start_aa": "Thr", "end_pos": 41, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr41", "evidence": [ { "id": "", "database": "GlyGen", "url": "https://data.glygen.org/" } ], "filter_code": "000000000000000010000.00000000001000.0.01000" }, { "glytoucan_ac": "", "type": "O-linked", "subtype": "other", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 92, "start_aa": "Thr", "end_pos": 92, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr92", "evidence": [ { "id": "", "database": "GlyGen", "url": "https://data.glygen.org/" } ], "filter_code": "000000000000000010000.00000000001000.0.01000" } ], "phosphorylation": [], "glycation": [], "keywords": [ "glycoprotein", "glycoprotein_predicted" ], "publication": [], "pathway": [ { "id": "bta:785831", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?bta:785831", "resource": "KEGG Pathway" } ], "orthologs": [ { "uniprot_canonical_ac": "F7ELW7-1", "protein_name": "Proline and serine rich 3", "gene_name": "Proser3", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MIHGDCSPFLPVCHGNCQLLPSASFIVSFHLPRQPLEMFPKVDNPLDHQEARTGATRSQKPQAPKATAANSAELSEESWPSSSGTASPPSTTEGQSTSPPLTLIDNEDSVVAKYINRFRKAQPTSREDRQPVGPTPADFWWLQPASSDLSSHLAAAGAGEPTGRSAVTGPCPTGMSSTSLASVPLQRVKQSLNSWNSAMLELETLSLQSRAAKLLERSKASLSSSSSSPSPNEASSSSFPISSDGLSPCSVTFNPDSNKSSSPKEPVLGAAPVPSQAIPAPRPASAQATLKPEEDILYQWRQRRKLEQSLQGAGDGTWVLPRTPALTTQTPVSAVNLGSKGTQPNCAPPWGSVAQPPPPQAFYMERPPLSGPSPHIWAPGTHGVLWAPQANPWIPLGMVPTTLLTSTLAPLASLPVPPTSTSAATAPISAPQVSIPGPPASAPPPCTSAPASTVPLPDNPQGPTTPELSSSVHPKKLSPKPRCVSASSRQETTGPDTAAFESPCSQLRGALSQVVTARLFSDSLEDMPPSEADSRKVKATSSQAKVPPPPPESRRGSKTESRKSKVTLSAEAGDPQPATAPKASTLSEVQSLEFKKSTPKKGAGDALTTAPPASSHAPSEDLLSQAARLLQAAEDSDGSEFPEDSVLRVLRAQRAELRQQKRNVDAQLSLLLDHTEDPGFSSPPARSPSSSPRMRLRREGASLEARRP", "length": 708 }, "evidence": [ { "id": "G3MXY1", "url": "https://omabrowser.org/oma/group/G3MXY1/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "Q2NL68-1", "protein_name": "Proline and serine-rich protein 3", "gene_name": "PROSER3", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MDRSLPVFSIQDSPFGDAPLGRSHYWPSQSQTWCPKTLSPSRSQRSRLPQAPKALATGPNSPELFEESWPSSSGTPSLPSTTEGQMWASPAPTLIDSGDSVVAKYINRFRQAQPTSREERQPAGPTPADFWWLQSDSPDPSSQSAAAGANKPEGRPHTAVPTAVNVTSASHAVAPLQEIKQNLHTWNSSLLDLETLSLQSRAARLLKRSKASISSSSSLSPSDASTSSFPTSSDGLSPFSETFIPDSSKGLGPRAPASPAPAQAQTPTPAPAPASSQAPLRPEDDILYQWRQRRKLEQAQGSKGDRAWVPPLTPALRTLAESLKAKALPPAAGSVIRKSEATPSPGACLQPEVPLSPAEQATTVKASPPAFQVGSPEALAPPPPAADHAPSEALLAQAALLLQAAEDSDGSEFQDDPVLQVLRAHRAELSRQKREADARLSFLLDQAEDLGSWSPPAGSPPRSPRRLLRREGDSLEARRL", "length": 480 }, "evidence": [ { "id": "G3MXY1", "url": "https://omabrowser.org/oma/group/G3MXY1/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "Q7TSA6-1", "protein_name": "Proline and serine-rich protein 3", "gene_name": "Proser3", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MFPKVDNPLGHQETRTGATRSQRPQAPKATAASSDELSEESWPSSSWTPSPASTTEGQSTSPPCNLIDNEDSIVAKYINRFRQAQPTSREDRQPAGPTSADFWWLQPTADSSGHLAAGAGEPTGRSAVTGPSPTGVSSTSLASAPLQKVKQSLNSWNSSLLDLETLSLQSRAARLLKRSKASLNDASSSSFPISSDGLSPSSVTFNPDSNKSSNPKEPVLGAPGPSQAIPAPRPASSQATLKPEDDILYQWRQRRKLEQSLQGAGDGTWVLPRMPALTTQTPPVSAVNLGSQDTQPNCTAPCGSVAQPPPSQAFYMERPPLSGPSPHIWAPGTHGVLWAPQANPWVSFGMLPTTLLTSTLAPLASFPVPPTSTSTTPAPTPTPQVCIPGPPTSAPPPCASTPASTLPLPDTPQGPAIPELSSSIQPKKVGPKPRRVSTSSHQKTTVPDTTAFEGPCSQLRGALSQVVTARLFPDSPEDTPPSEADFRKVQAIPSQAKVLRPPPESRRGSKTESRKSQVTLPADAGDPQPATAPKASTLLEVQPREFKMSAPRMGAGDPLTIVPPASSHAPSEDLLSQATKLLQAAEDSDGSEFQEDPVLQLLRAQRAELRQQKRWMPSYLSSWTTLKTRDLRLL", "length": 634 }, "evidence": [ { "id": "G3MXY1", "url": "https://omabrowser.org/oma/group/G3MXY1/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" } ], "go_annotation": {}, "pro_annotation": [], "site_annotation": [ { "start_pos": 154, "end_pos": 156, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [ { "pdb_id": "AF-G3MXY1-F1", "pdb_chain": "global", "start_pos": 1, "end_pos": 666, "overlap": "1.0", "method": "AlphaFold", "type": "alphafold", "resolution": -1.0, "url": "https://data.glygen.org/ln2downloads/pdb/current/AF-G3MXY1-F1.pdb", "url_external": "https://alphafold.ebi.ac.uk/entry/G3MXY1" } ], "lectin_list": [], "domain_list": [], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" }, { "name": "homologset.oma", "label": "OMA Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [ 41, 92, 225, 233, 385, 392, 411 ], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 154, "end_pos": 156 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 7 }, { "field": "total_sites", "count": 7 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 7 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "exact_sites", "count": 7 }, { "field": "exact_o_linked_sites", "count": 7 }, { "field": "fuzzy_sites", "count": 0 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_pos", "start_aa", "end_pos", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 7 }, { "field": "total_sites", "count": 7 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 7 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "exact_sites", "count": 7 }, { "field": "exact_o_linked_sites", "count": 7 }, { "field": "fuzzy_sites", "count": 0 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_pos", "start_aa", "end_pos", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ], "tool_support": { "graph_view": "yes" } }, { "uniprot_canonical_ac": "G3MXY2-1", "uniprot_ac": "G3MXY2", "uniprot_id": "G3MXY2_BOVIN", "mass": { "chemical_mass": 17130.0, "monoisotopic_mass": 17130.0 }, "refseq": { "ac": "XP_002692809", "name": "alanine and arginine-rich domain-containing protein", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_002692809" }, "gene_names": [ { "name": "AARD", "type": "recommended", "evidence": [ { "id": "G3MXY2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3MXY2" } ] }, { "name": "AARD", "type": "synonym", "evidence": [ { "id": "XP_002692809", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_002692809" } ] } ], "protein_names": [ { "name": "Alanine and arginine rich domain containing protein", "type": "synonym", "evidence": [ { "id": "G3MXY2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3MXY2/entry#names_and_taxonomy" } ] }, { "name": "alanine and arginine-rich domain-containing protein", "type": "synonym", "evidence": [ { "id": "XP_002692809", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_002692809" } ] } ], "function": [], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Bos taurus", "taxid": 9913, "evidence": [ { "database": "UniProtKB", "id": "G3MXY2", "url": "https://www.uniprot.org/uniprotkb/G3MXY2" } ], "common_name": "Bovine", "glygen_name": "Bovine", "reference_species": "Bos taurus [9913]" } ], 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"categories": [ "Protein Classification" ] }, { "id": "PF00891", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00891", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF02545", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF02545", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF08100", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF08100", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "G3MY50", "url": "https://www.uniprot.org/uniprotkb/G3MY50", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "G3MY50-1", "url": "https://www.uniprot.org/uniprotkb/G3MY50-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MLLCPVIGKLQHKRVVLASSSPRRREILSNAGLRFEVVPSRFKEKLHKASFATPQAYAVETAKQKALEVADRMYQKDLRAPDVVIGADTIVAVGGLILEKPVDKQDAYRMLSRLSGKEHSVFTGVAIVHCYTKDGQLDTEVSEFYEETTVKFSELSEEMLWEYIDSGEPMDKAGGYGIQALGGMLVEYVRGDFLNVVGFPLNRFCKELAHLYHGPRAHGAPRQVRHDSIPAVDTFEDLSDAEGGGSDPARAKEGLEPCGVQPQAPRPREADLNGVTDSQPPLPVGLLELMDGFKASKALLTACKLQVFDVLKERGPLAAADVAREIDASVGGTARLLDVCAALGLLDKSDRGYSNTEMASLHLASDGEQSLHGLAAYHDGPVWGAFTHLGRAVREGAAWTPEPLPQAPHKWSTEATLQFMRASHGLSKLTAQHVATAFDLSPFTSACHLGGCTGALAHKLVQEYPHLQVTIFALPEVIKLAGDFETNARPSERVHFVPGDLSSDSLPPADLYIVCSLLHDWPDDRLHGLLSRVSGCCKPGAGLLLAELAPAEEEDASGAARRPPGLRALGVGRPPRNPGQYQRLLQRLGFQDVQAACAAGLLHVVLGTRAPP", "length": 612, "header": "tr|G3MY50-1|G3MY50_BOVIN Isoform 1 of Acetylserotonin O-methyltransferase like OS=Bos taurus OX=9913 GN=ASMTL PE=3 SV=2 CANONICAL=G3MY50-1" }, "isoforms": [ { "isoform_ac": "G3MY50-1", "url": "https://www.uniprot.org/uniprotkb/G3MY50/entry", "sequence": { "sequence": "MLLCPVIGKLQHKRVVLASSSPRRREILSNAGLRFEVVPSRFKEKLHKASFATPQAYAVETAKQKALEVADRMYQKDLRAPDVVIGADTIVAVGGLILEKPVDKQDAYRMLSRLSGKEHSVFTGVAIVHCYTKDGQLDTEVSEFYEETTVKFSELSEEMLWEYIDSGEPMDKAGGYGIQALGGMLVEYVRGDFLNVVGFPLNRFCKELAHLYHGPRAHGAPRQVRHDSIPAVDTFEDLSDAEGGGSDPARAKEGLEPCGVQPQAPRPREADLNGVTDSQPPLPVGLLELMDGFKASKALLTACKLQVFDVLKERGPLAAADVAREIDASVGGTARLLDVCAALGLLDKSDRGYSNTEMASLHLASDGEQSLHGLAAYHDGPVWGAFTHLGRAVREGAAWTPEPLPQAPHKWSTEATLQFMRASHGLSKLTAQHVATAFDLSPFTSACHLGGCTGALAHKLVQEYPHLQVTIFALPEVIKLAGDFETNARPSERVHFVPGDLSSDSLPPADLYIVCSLLHDWPDDRLHGLLSRVSGCCKPGAGLLLAELAPAEEEDASGAARRPPGLRALGVGRPPRNPGQYQRLLQRLGFQDVQAACAAGLLHVVLGTRAPP", "length": 612, "header": "tr|G3MY50-1|G3MY50_BOVIN Isoform 1 of Acetylserotonin O-methyltransferase like OS=Bos taurus OX=9913 GN=ASMTL PE=3 SV=2 CANONICAL=G3MY50-1" }, "locus": { "chromosome": "26", "start_pos": 15185489, "end_pos": 15165077, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000063610.4", "url": "https://www.ensembl.org/id/ENSBTAT00000063610.4" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000054478.2", "url": "https://www.ensembl.org/id/ENSBTAP00000054478.2" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [], "orthologs": [ { "uniprot_canonical_ac": "E1BY36-1", "protein_name": "Acetylserotonin O-methyltransferase like", "gene_name": "ASMTL", "tax_id": 9031, "organism": "Gallus gallus", "sequence": { "sequence": "MVLSPVLGKLVSKRVVLASASPRRQEILTNVGLRFEVVPSWFKETLEKSSFAAPYEYAIETAKQKALEVANRMHVKHLRTPDIVIGADTIVTVDEQILEKPVDKQDAYRMLSRLSGKEHSVFTGVVIIHCSSKDNQLETEITDFYEETKVKFSDLSEELLWEYIHSGEPMDKAGGYGIQALGGMLVEYVHGDFLNVVGFPLNHFCKKLAELYCPPLKHTIQHIKHDSIPSVDTFESLSDGESESSSFKEHKGAIKLDSPSGVICNSENSSGVRTGSVVPLENQNGVSDSAAKVPSKILDLMDGFRASKALFVASKLKMFDHLKKKSPLKAVDIANEAGTSVCGTERLLDACTALGLLEKTPQGYSNTDSANTYLASDGEYSLHGYIIHSNDHLWPLFTHLESAVKEGSRQNHRAFGKKTEDLFNDYYQSQEVKQRFMAAMHSIARLTARDVATAFDLSEFKTACDLGGCTGALAHELIQIYPNMKVTVFDLPEVIANTSCFQPSEQRVASVTFVSGNFFTDDLPEADLYILSRVLHDWPDEKIHILLKKISAVCRPGSALLVAETVLDEQKIHPPRVVLQSLSMTEGKQRSGSEYKQLLEKYGFTNTQIKITGNLLDVVLCFKKSVILACTEIA", "length": 634 }, "evidence": [ { "id": "G3MY50", "url": "https://omabrowser.org/oma/group/G3MY50/", "database": "OMA" } ], "glygen_name": "Chicken", "common_name": "Chicken" }, { "uniprot_canonical_ac": "O95671-1", "protein_name": "Probable bifunctional dTTP/UTP pyrophosphatase/methyltransferase protein", "gene_name": "ASMTL", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MVLCPVIGKLLHKRVVLASASPRRQEILSNAGLRFEVVPSKFKEKLDKASFATPYGYAMETAKQKALEVANRLYQKDLRAPDVVIGADTIVTVGGLILEKPVDKQDAYRMLSRLSGREHSVFTGVAIVHCSSKDHQLDTRVSEFYEETKVKFSELSEELLWEYVHSGEPMDKAGGYGIQALGGMLVESVHGDFLNVVGFPLNHFCKQLVKLYYPPRPEDLRRSVKHDSIPAADTFEDLSDVEGGGSEPTQRDAGSRDEKAEAGEAGQATAEAECHRTRETLPPFPTRLLELIEGFMLSKGLLTACKLKVFDLLKDEAPQKAADIASKVDASACGMERLLDICAAMGLLEKTEQGYSNTETANVYLASDGEYSLHGFIMHNNDLTWNLFTYLEFAIREGTNQHHRALGKKAEDLFQDAYYQSPETRLRFMRAMHGMTKLTACQVATAFNLSRFSSACDVGGCTGALARELAREYPRMQVTVFDLPDIIELAAHFQPPGPQAVQIHFAAGDFFRDPLPSAELYVLCRILHDWPDDKVHKLLSRVAESCKPGAGLLLVETLLDEEKRVAQRALMQSLNMLVQTEGKERSLGEYQCLLELHGFHQVQVVHLGGVLDAILATKVAP", "length": 621 }, "evidence": [ { "id": "G3MY50", "url": "https://omabrowser.org/oma/group/G3MY50/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" } ], "go_annotation": { "categories": [ { "name": "Molecular Function", "total": 3, "go_terms": [ { "name": "protein dimerization activity", "id": "GO:0046983", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0046983", "evidence": [ { "database": "UniProtKB", "id": "G3MY50", "url": "https://www.uniprot.org/uniprotkb/G3MY50" } ], "pmid": "" }, { "name": "O-methyltransferase activity", "id": "GO:0008171", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008171", "evidence": [ { "database": "UniProtKB", "id": "G3MY50", "url": "https://www.uniprot.org/uniprotkb/G3MY50" } ], "pmid": "" }, { "name": "nucleoside triphosphate diphosphatase activity", "id": "GO:0047429", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0047429", "evidence": [ { "database": "UniProtKB", "id": "G3MY50", "url": "https://www.uniprot.org/uniprotkb/G3MY50" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 1, "go_terms": [ { "name": "methylation", "id": "GO:0032259", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0032259", "evidence": [ { "database": "UniProtKB", "id": "G3MY50", "url": "https://www.uniprot.org/uniprotkb/G3MY50" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [ { "pdb_id": "AF-G3MY50-F1", "pdb_chain": "global", "start_pos": 1, "end_pos": 612, "overlap": "1.0", "method": "AlphaFold", "type": "alphafold", "resolution": -1.0, "url": "https://data.glygen.org/ln2downloads/pdb/current/AF-G3MY50-F1.pdb", "url_external": "https://alphafold.ebi.ac.uk/entry/G3MY50" } ], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "G3MY50", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3MY50" }, { "id": "PF00891", "database": "Pfam", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00891" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "O-methyltransferase C-terminal", "eco_id": "ECO_0000259", "start_pos": 409, "end_pos": 591, "start_aa": "His", "end_aa": "Gln", "glycosite_overlap": [] }, { "evidence": [ { "id": "G3MY50", "database": 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"field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ], "tool_support": { "graph_view": "yes" } }, { "uniprot_canonical_ac": "G3MY54-1", "uniprot_ac": "G3MY54", "uniprot_id": "G3MY54_BOVIN", "mass": { "chemical_mass": 35062.0, "monoisotopic_mass": 35062.0 }, "refseq": { "ac": "NP_001377094", "name": "olfactory receptor family 1 subfamily J member 4B", "summary": "Olfactory receptors interact with odorant molecules in the nose, to initiate a neuronal response that triggers the perception of a smell. The olfactory receptor proteins are members of a large family of G-protein-coupled receptors (GPCR) arising from single coding-exon genes. Olfactory receptors share a 7-transmembrane domain structure with many neurotransmitter and hormone receptors and are responsible for the recognition and G protein-mediated transduction of odorant signals. The olfactory receptor gene family is the largest in the genome. [provided by RefSeq, Jul 2008].", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001377094" }, "gene_names": [ { "name": "OR1J4B", "type": "recommended", "evidence": [ { "id": "G3MY54", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3MY54" } ] }, { "name": "OR1J4B", "type": "synonym", "evidence": [ { "id": "NP_001377094", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001377094" } ] } ], "protein_names": [ { "name": "Olfactory receptor family 1 subfamily J member 4B", "type": "synonym", "evidence": [ { "id": "G3MY54", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3MY54/entry#names_and_taxonomy" } ] }, { "name": "olfactory receptor 1J4", "type": "synonym", "evidence": [ { "id": "NP_001377094", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001377094" } ] }, { "name": "olfactory receptor family 1 subfamily J member 4B", "type": "synonym", "evidence": [ { "id": "NP_001377094", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001377094" } ] } ], "function": [ { "annotation": "Olfactory receptors interact with odorant molecules in the nose, to initiate a neuronal response that triggers the perception of a smell. The olfactory receptor proteins are members of a large family of G-protein-coupled receptors (GPCR) arising from single coding-exon genes. Olfactory receptors share a 7-transmembrane domain structure with many neurotransmitter and hormone receptors and are responsible for the recognition and G protein-mediated transduction of odorant signals. The olfactory receptor gene family is the largest in the genome. [provided by RefSeq, Jul 2008].", "evidence": [ { "database": "RefSeq", "id": "NP_001377094", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001377094" } ] }, { "annotation": "Putative odorant or sperm cell receptor.", "evidence": [ { "database": "UniProtKB", "id": "G3MY54", "url": "https://www.uniprot.org/uniprotkb/G3MY54#function" }, { "database": "UniProtKB", "id": "ARBA00003929", "url": "https://www.uniprot.org/uniprotkb/ARBA00003929#function" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Bos taurus", "taxid": 9913, "evidence": [ { "database": "UniProtKB", "id": "G3MY54", "url": "https://www.uniprot.org/uniprotkb/G3MY54" } ], "common_name": "Bovine", "glygen_name": "Bovine", "reference_species": "Bos taurus [9913]" } ], "gene": [ { "name": "OR1J4B", "url": "https://www.uniprot.org/uniprotkb/G3MY54", "locus": { "chromosome": "11", "start_pos": 93672201, "end_pos": 93673142, "strand": "+", "evidence": [ { "database": "Ensembl Gene", "id": "ENSBTAG00000063038", "url": "https://www.ensembl.org/id/ENSBTAG00000063038" } ] } } ], "crossref": [ { "id": "G3MY54", "url": "https://alphafold.ebi.ac.uk/entry/G3MY54", "database": "AlphaFoldDB", "categories": [] }, { "id": "cd15918", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd15918", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "539172", "url": "https://www.ncbi.nlm.nih.gov/gene/539172", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR000276", "url": "https://www.ebi.ac.uk/interpro/entry/IPR000276", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR000725", "url": "https://www.ebi.ac.uk/interpro/entry/IPR000725", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR017452", "url": "https://www.ebi.ac.uk/interpro/entry/IPR017452", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "bta:539172", "url": "https://www.genome.jp/dbget-bin/www_bget?bta:539172", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "TIASMIY", "url": "https://omabrowser.org/oma/group/TIASMIY/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "G3MY54", "url": "https://www.orthodb.org/?gene=G3MY54", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR48001", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR48001", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF13853", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF13853", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "NP_001377094", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001377094", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "G3MY54", "url": "https://www.uniprot.org/uniprotkb/G3MY54", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "G3MY54-1", "url": "https://www.uniprot.org/uniprotkb/G3MY54-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MKREKNSSVSEFLLLGLPIRPEQQGMFFALFLGVYLTTVLGNLLILLLIRLDTRLHTPMYFFLSHLALTDVSFSSVTVPKMLINMHTRDQSIPYAGCVTQMYFFLFFTDLDDFLLTSMAYDRYVAICHPLHYSTVMRQGLCTLLVTVSWILSCANALCHTLLLTRLSFCADHSIPHFFCDLDALMKLSCSDTSLNELAIFTAGVVVIILPLICILTSYGRIGATILKVPSTKGICKALSTCGSHLSVVSLYYGTIIGLYFFPSSNTSRDKSTIASVMYTVVTPLLNPFIYSLRNRDMKGALERLLHRAKILSQ", "length": 313, "header": "tr|G3MY54-1|G3MY54_BOVIN Isoform 1 of Olfactory receptor family 1 subfamily J member 4B OS=Bos taurus OX=9913 GN=OR1J4B PE=3 SV=1 CANONICAL=G3MY54-1" }, "isoforms": [ { "isoform_ac": "G3MY54-1", "url": "https://www.uniprot.org/uniprotkb/G3MY54/entry", "sequence": { "sequence": 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"evidence": [ { "database": "UniProtKB", "id": "G3MY54", "url": "https://www.uniprot.org/uniprotkb/G3MY54" } ], "pmid": "" }, { "name": "olfactory receptor activity", "id": "GO:0004984", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0004984", "evidence": [ { "database": "UniProtKB", "id": "G3MY54", "url": "https://www.uniprot.org/uniprotkb/G3MY54" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 1, "go_terms": [ { "name": "plasma membrane", "id": "GO:0005886", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005886", "evidence": [ { "database": "UniProtKB", "id": "G3MY54", "url": "https://www.uniprot.org/uniprotkb/G3MY54" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 1, "go_terms": [ { "name": "signal transduction", "id": "GO:0007165", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007165", "evidence": [ { "database": "UniProtKB", "id": "G3MY54", "url": "https://www.uniprot.org/uniprotkb/G3MY54" } ], "pmid": "" } ] } ] }, "pro_annotation": [], 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phosphatase 1 regulatory subunit 27", "type": "recommended", "evidence": [ { "id": "G3MY56", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3MY56/entry#names_and_taxonomy" } ] }, { "name": "Dysferlin-interacting protein 1", "type": "synonym", "evidence": [ { "id": "G3MY56", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3MY56/entry#names_and_taxonomy" } ] } ], "function": [ { "annotation": "Inhibits phosphatase activity of protein phosphatase 1 (PP1) complexes.", "evidence": [ { "database": "UniProtKB", "id": "G3MY56", "url": "https://www.uniprot.org/uniprotkb/G3MY56#function" }, { "database": "UniProtKB", "id": "ARBA00060048", "url": "https://www.uniprot.org/uniprotkb/ARBA00060048#function" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Bos taurus", "taxid": 9913, "evidence": [ { "database": "UniProtKB", "id": "G3MY56", "url": 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"categories": [ "Protein Classification" ] }, { "id": "IPR053080", "url": "https://www.ebi.ac.uk/interpro/entry/IPR053080", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "QRDATND", "url": "https://omabrowser.org/oma/group/QRDATND/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "G3MY56", "url": "https://www.orthodb.org/?gene=G3MY56", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR46899", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR46899", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR46899:SF3", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR46899:SF3", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF12796", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF12796", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "G3MY56", "url": 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"MILRAGLERLSFSPSGASMTAQLYIALPALYKKKVPWPTGARRALWRRCWRSPSVRRACTQFGSVHLPSLSRRVPTGVAQTIAARMPSRTARYARYSPRQRRRRLLADRSVRFPNDVLFLDHIRQGDLEQVGRFIRTRKVSLDTIYPSGLAALHEAVLSGNLECVKLLVKYGADIHQRDETGWTPLHIACSDGYPDIARYLISLGADREAANDDGDLPSDLIDPEFKDLVELFKGTKMD", "length": 239, "header": "tr|G3MY56-1|G3MY56_BOVIN Isoform 1 of Protein phosphatase 1 regulatory subunit 27 OS=Bos taurus OX=9913 GN=PPP1R27 PE=4 SV=2 CANONICAL=G3MY56-1" }, "locus": { "chromosome": "19", "start_pos": 51050067, "end_pos": 51048990, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000065817.3", "url": "https://www.ensembl.org/id/ENSBTAT00000065817.3" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000054484.2", "url": "https://www.ensembl.org/id/ENSBTAP00000054484.2" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [], "orthologs": [ { "uniprot_canonical_ac": "A0A286ZIK2-1", "protein_name": "Protein phosphatase 1 regulatory 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The olfactory receptor proteins are members of a large family of G-protein-coupled receptors (GPCR) arising from single coding-exon genes. Olfactory receptors share a 7-transmembrane domain structure with many neurotransmitter and hormone receptors and are responsible for the recognition and G protein-mediated transduction of odorant signals. The olfactory receptor gene family is the largest in the genome. [provided by RefSeq, Jul 2008].", "evidence": [ { "database": "RefSeq", "id": "NP_001377653", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001377653" } ] }, { "annotation": "Putative odorant or sperm cell receptor.", "evidence": [ { "database": "UniProtKB", "id": "G3MY72", "url": "https://www.uniprot.org/uniprotkb/G3MY72#function" }, { "database": "UniProtKB", "id": "ARBA00003929", "url": "https://www.uniprot.org/uniprotkb/ARBA00003929#function" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Bos taurus", "taxid": 9913, "evidence": [ { "database": "UniProtKB", "id": "G3MY72", "url": "https://www.uniprot.org/uniprotkb/G3MY72" } ], "common_name": "Bovine", "glygen_name": "Bovine", "reference_species": "Bos taurus [9913]" } ], "gene": [ { "name": "OR10G1", "url": "https://www.uniprot.org/uniprotkb/G3MY72", "locus": { "chromosome": "10", "start_pos": 25582907, "end_pos": 25581951, "strand": "-", "evidence": 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"CLGELINEDIHTWNSLCRQEITIKTYDNSIPISESSKKIRNQQYLTITFPKSSQPGGNKRLRPSEIQVTVPRHDKRNLDELQKPAHIWIRHSLRKKFQSPSINLIVRRQASFRHPYTHITHSKKAESKKYKDDKKETALKKISKKDTGPHEVDEKPKRRNKADKTPSKSSHGSQLSKKSKSKSETNPESKDSISVSIKHQKKEKRYSKDSKEMDFESTSTKKYSKSSKNNSDAVSETCSKNSSNVGLMVHLGESDAESMEFDMWLKNYSQNNSKKPTKKDAKKDAKGKGSDAESVDSKDAKKDKKGATKDTKKGAKKDTESTDAESGDSKDAKKGKKESKKDKKKDAKKDAASDAESGDSKDAKKDSKKGKKDSKKDNKKKDAKKDAESTDAESGDSKDAKKDSKKGKKDSKKDDKKKDAKKDAESTDAESGDSKNAKKDSKKGKKDDKKKDAKKDAVSTDADSESEGDAKKSKKDSKKDKKDLKKDDQKKPAMKSKESTETESDWESKKVKRDSKKDTKKTAKKATESSGAESDVSSKRYLKKTEMFKSSDAESEESLFKPGSKKRVDESDATSTDSKKDAVEPKRGIKMPSRRTTFKEKGKKIGTGRVPPSRERPPLPPCEPILPSPRVKRLCRCQMPPPPPKPRYAPLPEAKWIHKLL", "length": 661, "header": "tr|G3MY76-1|G3MY76_BOVIN Isoform 1 of Cylicin 1 OS=Bos taurus OX=9913 GN=CYLC1 PE=4 SV=3 CANONICAL=G3MY76-1" }, "isoforms": [ { "isoform_ac": "G3MY76-1", "url": "https://www.uniprot.org/uniprotkb/G3MY76/entry", "sequence": { "sequence": "CLGELINEDIHTWNSLCRQEITIKTYDNSIPISESSKKIRNQQYLTITFPKSSQPGGNKRLRPSEIQVTVPRHDKRNLDELQKPAHIWIRHSLRKKFQSPSINLIVRRQASFRHPYTHITHSKKAESKKYKDDKKETALKKISKKDTGPHEVDEKPKRRNKADKTPSKSSHGSQLSKKSKSKSETNPESKDSISVSIKHQKKEKRYSKDSKEMDFESTSTKKYSKSSKNNSDAVSETCSKNSSNVGLMVHLGESDAESMEFDMWLKNYSQNNSKKPTKKDAKKDAKGKGSDAESVDSKDAKKDKKGATKDTKKGAKKDTESTDAESGDSKDAKKGKKESKKDKKKDAKKDAASDAESGDSKDAKKDSKKGKKDSKKDNKKKDAKKDAESTDAESGDSKDAKKDSKKGKKDSKKDDKKKDAKKDAESTDAESGDSKNAKKDSKKGKKDDKKKDAKKDAVSTDADSESEGDAKKSKKDSKKDKKDLKKDDQKKPAMKSKESTETESDWESKKVKRDSKKDTKKTAKKATESSGAESDVSSKRYLKKTEMFKSSDAESEESLFKPGSKKRVDESDATSTDSKKDAVEPKRGIKMPSRRTTFKEKGKKIGTGRVPPSRERPPLPPCEPILPSPRVKRLCRCQMPPPPPKPRYAPLPEAKWIHKLL", "length": 661, "header": "tr|G3MY76-1|G3MY76_BOVIN Isoform 1 of Cylicin 1 OS=Bos taurus OX=9913 GN=CYLC1 PE=4 SV=3 CANONICAL=G3MY76-1" }, "locus": { "chromosome": "X", "start_pos": 68923767, "end_pos": 68899689, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000063918.3", "url": "https://www.ensembl.org/id/ENSBTAT00000063918.3" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000054504.3", "url": "https://www.ensembl.org/id/ENSBTAP00000054504.3" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [], "orthologs": [], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 4, "go_terms": [ { "name": "sperm head", "id": "GO:0061827", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0061827", "evidence": [ { "database": "UniProtKB", "id": "G3MY76", "url": "https://www.uniprot.org/uniprotkb/G3MY76" } ], "pmid": "" }, { "name": "acrosomal matrix", "id": "GO:0043159", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0043159", "evidence": [ { "database": "UniProtKB", "id": "G3MY76", "url": "https://www.uniprot.org/uniprotkb/G3MY76" } ], "pmid": "" }, { "name": "cytoskeletal calyx", "id": "GO:0033150", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0033150", "evidence": [ { "database": "UniProtKB", "id": "G3MY76", "url": "https://www.uniprot.org/uniprotkb/G3MY76" } ], "pmid": "" }, { "name": "sperm glycocalyx", "id": "GO:0120238", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0120238", "evidence": [ { "database": "UniProtKB", "id": "G3MY76", "url": "https://www.uniprot.org/uniprotkb/G3MY76" } ], "pmid": "" } ] }, { "name": "Molecular Function", "total": 1, "go_terms": [ { "name": "structural constituent of cytoskeleton", "id": "GO:0005200", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005200", "evidence": [ { "database": "UniProtKB", "id": "G3MY76", "url": "https://www.uniprot.org/uniprotkb/G3MY76" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 1, "go_terms": [ { "name": "acrosome assembly", "id": "GO:0001675", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0001675", "evidence": [ { "database": "UniProtKB", "id": "G3MY76", "url": "https://www.uniprot.org/uniprotkb/G3MY76" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { 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"Protein Classification" ] }, { "id": "PTHR23349:SF108", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR23349:SF108", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00010", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00010", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "XP_005206856", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_005206856", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "G3MY92", "url": "https://www.uniprot.org/uniprotkb/G3MY92", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "G3MY92-1", "url": "https://www.uniprot.org/uniprotkb/G3MY92-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MEKRPQDGLLTLPHHLSQVPLGVPRSLPRLLMRDSFRVSVSWEPALGGGGAPRRPYLPLRLDGAFEPAFLRKRNERERQRVRCVNEGYARLRDHLPREVADRRLSKVETLRAAIGYIKQLQEVLERHAPGQEGAAGAGSSRRAECNSDGESKASSAPSPSSEPEDGAS", "length": 168, "header": 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"name": "regulation of transcription by RNA polymerase II", "id": "GO:0006357", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006357", "evidence": [ { "database": "UniProtKB", "id": "G3MY92", "url": "https://www.uniprot.org/uniprotkb/G3MY92" } ], "pmid": "" }, { "name": "animal organ development", "id": "GO:0048513", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0048513", "evidence": [ { "database": "UniProtKB", "id": "G3MY92", "url": "https://www.uniprot.org/uniprotkb/G3MY92" } ], "pmid": "" } ] }, { "name": "Molecular Function", "total": 4, "go_terms": [ { "name": "protein dimerization activity", "id": "GO:0046983", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0046983", "evidence": [ { "database": "UniProtKB", "id": "G3MY92", "url": "https://www.uniprot.org/uniprotkb/G3MY92" } ], "pmid": "" }, { "name": "RNA polymerase II transcription regulatory region sequence-specific DNA binding", "id": "GO:0000977", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000977", "evidence": [ { 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"pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [ { "pdb_id": "AF-G3MY92-F1", "pdb_chain": "global", "start_pos": 1, "end_pos": 168, "overlap": "1.0", "method": "AlphaFold", "type": "alphafold", "resolution": -1.0, "url": "https://data.glygen.org/ln2downloads/pdb/current/AF-G3MY92-F1.pdb", "url_external": "https://alphafold.ebi.ac.uk/entry/G3MY92" } ], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "G3MY92", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3MY92" }, { "id": "PS50888", "database": "PROSITE", "url": "https://prosite.expasy.org/PS50888" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "BHLH", "eco_id": "ECO_0000259", "start_pos": 68, "end_pos": 120, "start_aa": "Ala", "end_aa": "Leu", "glycosite_overlap": [] } ], "binding_sites": [], "synthesized_glycans": [], 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"Protein Classification" ] }, { "id": "bta:785478", "url": "https://www.genome.jp/dbget-bin/www_bget?bta:785478", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "IYGQTAC", "url": "https://omabrowser.org/oma/group/IYGQTAC/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "G3MY95", "url": "https://www.orthodb.org/?gene=G3MY95", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR24201", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR24201", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR24201:SF15", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR24201:SF15", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF12796", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF12796", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "XP_002697314", "url": 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"evidence": [ { "id": "G3MY95", "url": "https://omabrowser.org/oma/group/G3MY95/", "database": "OMA" } ], "glygen_name": "Hamster", "common_name": "Chinese hamster" }, { "uniprot_canonical_ac": "B4E2M5-1", "protein_name": "Ankyrin repeat domain-containing protein 66", "gene_name": "ANKRD66", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MELAKMSDMTKLHQAVAAGDYSLVKKILKKGLCDPNYKDVDWNDRTPLHWAAIKGQMEVIRLLIEYGARPCLVTSVGWTPAHFAAEAGHLNILKTLHALHAAIDAPDFFGDTPKRIAQIYGQKACVAFLEKAEPECQDHRCAAQQKGLPLDERDEDWDAKKRELELSLPSLNQNMNKKNKKSRGPTRPSNTKGRRV", "length": 196 }, "evidence": [ { "id": "G3MY95", "url": "https://omabrowser.org/oma/group/G3MY95/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "J3QNN4-1", "protein_name": "Ankyrin repeat domain 66", "gene_name": "Ankrd66", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": 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"monoisotopic_mass": 94610.0 }, "refseq": {}, "gene_names": [ { "name": "GARIN5B", "type": "recommended", "evidence": [ { "id": "G3MY97", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3MY97" } ] } ], "protein_names": [ { "name": "Golgi associated RAB2 interactor protein-like Rab2B-binding domain-containing protein", "type": "recommended", "evidence": [ { "id": "G3MY97", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3MY97/entry#names_and_taxonomy" } ] } ], "function": [], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Bos taurus", "taxid": 9913, "evidence": [ { "database": "UniProtKB", "id": "G3MY97", "url": "https://www.uniprot.org/uniprotkb/G3MY97" } ], "common_name": "Bovine", "glygen_name": "Bovine", "reference_species": "Bos taurus [9913]" } ], "gene": [ { "name": "GARIN5B", "url": "https://www.uniprot.org/uniprotkb/G3MY97", "locus": {} } ], "crossref": [ { "id": "G3MY97", "url": "https://alphafold.ebi.ac.uk/entry/G3MY97", "database": "AlphaFoldDB", "categories": [] }, { "id": "ENSBTAG00000044157", "url": "https://bgee.org/?page=gene&gene_id=ENSBTAG00000044157", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "IPR022168", "url": "https://www.ebi.ac.uk/interpro/entry/IPR022168", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "PTHR22574", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR22574", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR22574:SF12", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR22574:SF12", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF12480", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF12480", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "G3MY97", "url": "https://www.uniprot.org/uniprotkb/G3MY97", "database": "UniProtKB", 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"MNRLRNLRRPEPLRGPPQWVPTLGELQKTLQQGEHLPLRPLPMFESNFVQVTNRGAPVYVHHRTNRVTMGVAASLPGLVLPDMLLMAQPPEDRECSNLVLTRMIPLDLAHLYVHDLSAWRLKLRLVTGRYYYLELDAPDSEVGFLFDRWMRLISQLQQPATSWAPRTLHTPPTGLSHLGPPASTWRLQVPSHRRHSVTTAEPTFPYKILTAQRQKAKTLKRKFKSQAVGDSLPLVWSQLQHVDARKKSTEKKPQSDLPSGRLKTEIQVSEKPSITIRTIFSIISNTPDHMESSPKGCSDSEGGACLAGLLETPLHCISEDSPEMPLLGTCDDLDMCAWQQHVDNLMDPETSTMSSCSIHPAAYTPNFPSFNKKARPLPPNWKPLAVPTAPHKAPFILDQSKRVSAMPAALQMSTAPGPSQKATAYPPVPQKAPFQKPPHVPTVPQKAPAMPGPSQKPRHAPAIPQKPPVMAVPSQRAPGTLGVSPKAVSHPAPNRKSVFLPAPSQKGLTSPTQHRMTLGPDSVSVVPSRSHRGDVLEKRKPEEKPEPVKLMGTKEKNVVETRTQKTTVEVPFTTTEKKSEEVLIRRAQEIAVDGLKGKGKLEDRVHMMKEEIDLDMPGFKSKEVGQQKKWVKTKKLAIQQAPQEQTRPFSVEGLTLAKLMIIAGSKDPTLRSALVNLPSWLSTSQGCDLSMMGRVPLGPTHLSMLEETLVGVREQPQLGVRVEEMPQDSKGPSNVSSRPRRAASSPKMNVASQTPIPLPSTRWEDIPESPTSLTPISKMEARVSQQPRRVSQEPERGPDQGPVATVGSNLEILLPTLLEIESMKDEASKVEKIKKELGAFAPSPRYLAVAMILSTW", "length": 856, "header": "tr|G3MY97-1|G3MY97_BOVIN Isoform 1 of Golgi associated RAB2 interactor protein-like Rab2B-binding domain-containing protein OS=Bos taurus OX=9913 GN=GARIN5B PE=3 SV=3 CANONICAL=G3MY97-1" }, "isoforms": [ { "isoform_ac": "G3MY97-1", "url": "https://www.uniprot.org/uniprotkb/G3MY97/entry", "sequence": { "sequence": "MNRLRNLRRPEPLRGPPQWVPTLGELQKTLQQGEHLPLRPLPMFESNFVQVTNRGAPVYVHHRTNRVTMGVAASLPGLVLPDMLLMAQPPEDRECSNLVLTRMIPLDLAHLYVHDLSAWRLKLRLVTGRYYYLELDAPDSEVGFLFDRWMRLISQLQQPATSWAPRTLHTPPTGLSHLGPPASTWRLQVPSHRRHSVTTAEPTFPYKILTAQRQKAKTLKRKFKSQAVGDSLPLVWSQLQHVDARKKSTEKKPQSDLPSGRLKTEIQVSEKPSITIRTIFSIISNTPDHMESSPKGCSDSEGGACLAGLLETPLHCISEDSPEMPLLGTCDDLDMCAWQQHVDNLMDPETSTMSSCSIHPAAYTPNFPSFNKKARPLPPNWKPLAVPTAPHKAPFILDQSKRVSAMPAALQMSTAPGPSQKATAYPPVPQKAPFQKPPHVPTVPQKAPAMPGPSQKPRHAPAIPQKPPVMAVPSQRAPGTLGVSPKAVSHPAPNRKSVFLPAPSQKGLTSPTQHRMTLGPDSVSVVPSRSHRGDVLEKRKPEEKPEPVKLMGTKEKNVVETRTQKTTVEVPFTTTEKKSEEVLIRRAQEIAVDGLKGKGKLEDRVHMMKEEIDLDMPGFKSKEVGQQKKWVKTKKLAIQQAPQEQTRPFSVEGLTLAKLMIIAGSKDPTLRSALVNLPSWLSTSQGCDLSMMGRVPLGPTHLSMLEETLVGVREQPQLGVRVEEMPQDSKGPSNVSSRPRRAASSPKMNVASQTPIPLPSTRWEDIPESPTSLTPISKMEARVSQQPRRVSQEPERGPDQGPVATVGSNLEILLPTLLEIESMKDEASKVEKIKKELGAFAPSPRYLAVAMILSTW", "length": 856, "header": "tr|G3MY97-1|G3MY97_BOVIN Isoform 1 of Golgi associated RAB2 interactor protein-like Rab2B-binding domain-containing protein OS=Bos taurus OX=9913 GN=GARIN5B PE=3 SV=3 CANONICAL=G3MY97-1" }, "locus": { "chromosome": "18", "start_pos": 62122164, "end_pos": 62118304, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000064126.3", "url": "https://www.ensembl.org/id/ENSBTAT00000064126.3" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000054526.3", "url": "https://www.ensembl.org/id/ENSBTAP00000054526.3" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [], "orthologs": [], "go_annotation": {}, "pro_annotation": [], "site_annotation": [ { "start_pos": 734, "end_pos": 736, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [ { "pdb_id": "AF-G3MY97-F1", "pdb_chain": "global", "start_pos": 1, "end_pos": 856, "overlap": "1.0", "method": "AlphaFold", "type": "alphafold", "resolution": -1.0, "url": "https://data.glygen.org/ln2downloads/pdb/current/AF-G3MY97-F1.pdb", "url_external": "https://alphafold.ebi.ac.uk/entry/G3MY97" } ], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "G3MY97", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3MY97" }, { "id": "PF12480", "database": "Pfam", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF12480" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "Golgi associated RAB2 interactor protein-like Rab2B-binding", "eco_id": "ECO_0000259", "start_pos": 98, "end_pos": 165, "start_aa": "Leu", "end_aa": "Pro", "glycosite_overlap": [] } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 734, "end_pos": 736 } ] }, "class_list": [], 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"total", "count": 0 } ], "sort_fields": [] } ], "tool_support": { "graph_view": "yes" } }, { "uniprot_canonical_ac": "G3MY98-1", "uniprot_ac": "G3MY98", "uniprot_id": "G3MY98_BOVIN", "mass": { "chemical_mass": 34406.0, "monoisotopic_mass": 34406.0 }, "refseq": { "ac": "NP_001377598", "name": "olfactory receptor family 10 subfamily D member 4", "summary": "Olfactory receptors interact with odorant molecules in the nose, to initiate a neuronal response that triggers the perception of a smell. The olfactory receptor proteins are members of a large family of G-protein-coupled receptors (GPCR) arising from single coding-exon genes. Olfactory receptors share a 7-transmembrane domain structure with many neurotransmitter and hormone receptors and are responsible for the recognition and G protein-mediated transduction of odorant signals. The olfactory receptor gene family is the largest in the genome. [provided by RefSeq, Jul 2008].", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001377598" }, "gene_names": [ { "name": "OR10D4", "type": "recommended", "evidence": [ { "id": "G3MY98", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3MY98" } ] }, { "name": "OR10D4", "type": "synonym", "evidence": [ { "id": "NP_001377598", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001377598" } ] } ], "protein_names": [ { "name": "Olfactory receptor family 10 subfamily D member 4", "type": "synonym", "evidence": [ { "id": "G3MY98", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3MY98/entry#names_and_taxonomy" } ] }, { "name": "olfactory receptor family 10 subfamily D member 4", "type": "synonym", "evidence": [ { "id": "NP_001377598", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001377598" } ] }, { "name": "putative olfactory receptor 10D4", "type": "synonym", "evidence": [ { "id": "NP_001377598", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001377598" } ] } ], "function": [ { "annotation": "Olfactory receptors interact with odorant molecules in the nose, to initiate a neuronal response that triggers the perception of a smell. The olfactory receptor proteins are members of a large family of G-protein-coupled receptors (GPCR) arising from single coding-exon genes. Olfactory receptors share a 7-transmembrane domain structure with many neurotransmitter and hormone receptors and are responsible for the recognition and G protein-mediated transduction of odorant signals. The olfactory receptor gene family is the largest in the genome. [provided by RefSeq, Jul 2008].", "evidence": [ { "database": "RefSeq", "id": "NP_001377598", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001377598" } ] }, { "annotation": "Putative odorant or sperm cell receptor.", "evidence": [ { "database": "UniProtKB", "id": "G3MY98", "url": "https://www.uniprot.org/uniprotkb/G3MY98#function" }, { "database": "UniProtKB", "id": "ARBA00003929", "url": "https://www.uniprot.org/uniprotkb/ARBA00003929#function" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Bos taurus", "taxid": 9913, "evidence": [ { "database": "UniProtKB", "id": "G3MY98", "url": "https://www.uniprot.org/uniprotkb/G3MY98" } ], "common_name": "Bovine", "glygen_name": "Bovine", "reference_species": "Bos taurus [9913]" } ], "gene": [ { "name": "OR10D4", "url": "https://www.uniprot.org/uniprotkb/G3MY98", "locus": { "chromosome": "29", "start_pos": 26808596, "end_pos": 26809531, "strand": "+", "evidence": [ { "database": "Ensembl Gene", "id": "ENSBTAG00000048192", "url": "https://www.ensembl.org/id/ENSBTAG00000048192" } ] } } ], "crossref": [ { "id": "G3MY98", "url": "https://alphafold.ebi.ac.uk/entry/G3MY98", "database": "AlphaFoldDB", "categories": [] }, { "id": "ENSBTAG00000048192", "url": "https://bgee.org/?page=gene&gene_id=ENSBTAG00000048192", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "cd15228", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd15228", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "100299320", "url": "https://www.ncbi.nlm.nih.gov/gene/100299320", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR000276", "url": "https://www.ebi.ac.uk/interpro/entry/IPR000276", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR000725", "url": "https://www.ebi.ac.uk/interpro/entry/IPR000725", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR017452", "url": "https://www.ebi.ac.uk/interpro/entry/IPR017452", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "bta:100299320", "url": "https://www.genome.jp/dbget-bin/www_bget?bta:100299320", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "VFPKKTF", "url": "https://omabrowser.org/oma/group/VFPKKTF/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "G3MY98", "url": "https://www.orthodb.org/?gene=G3MY98", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR26453", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR26453", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF13853", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF13853", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "NP_001377598", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001377598", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "G3MY98", "url": "https://www.uniprot.org/uniprotkb/G3MY98", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "G3MY98-1", "url": "https://www.uniprot.org/uniprotkb/G3MY98-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MRNHTVVTEYILLGIPETEGLETVLFSLFSSLYLCTVLGNVLILSAIISSSRLHTPMYFFLANLSVFDLGFSSTTAPKMLSYLSGLSQGISFQGCATQLFFYHFLGCTECFLYTVMAYDRFVAICFPLRYMVIMNHRVCTILATGTWIGGCIHAIILTSLTFQLSYCGSNKVSYYFCDIPAILPLACGDTSLAQRVGFTNVGLLSLICFFLILVSYTRIGIAISKILSAEGRQRAFSTCSAHMTAILCAYGPVIIIYLQPNPSALLGAIIQILNNHVTPMLNPLIYSLRNQDVKSALRNAFPKRCFTLKKN", "length": 311, "header": "tr|G3MY98-1|G3MY98_BOVIN Isoform 1 of Olfactory receptor family 10 subfamily D member 4 OS=Bos taurus OX=9913 GN=OR10D4 PE=3 SV=2 CANONICAL=G3MY98-1" }, "isoforms": [ { "isoform_ac": "G3MY98-1", "url": "https://www.uniprot.org/uniprotkb/G3MY98/entry", "sequence": { "sequence": "MRNHTVVTEYILLGIPETEGLETVLFSLFSSLYLCTVLGNVLILSAIISSSRLHTPMYFFLANLSVFDLGFSSTTAPKMLSYLSGLSQGISFQGCATQLFFYHFLGCTECFLYTVMAYDRFVAICFPLRYMVIMNHRVCTILATGTWIGGCIHAIILTSLTFQLSYCGSNKVSYYFCDIPAILPLACGDTSLAQRVGFTNVGLLSLICFFLILVSYTRIGIAISKILSAEGRQRAFSTCSAHMTAILCAYGPVIIIYLQPNPSALLGAIIQILNNHVTPMLNPLIYSLRNQDVKSALRNAFPKRCFTLKKN", "length": 311, "header": "tr|G3MY98-1|G3MY98_BOVIN Isoform 1 of Olfactory receptor family 10 subfamily D member 4 OS=Bos taurus OX=9913 GN=OR10D4 PE=3 SV=2 CANONICAL=G3MY98-1" }, "locus": { "chromosome": "29", "start_pos": 26809531, "end_pos": 26808599, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000064708.2", "url": "https://www.ensembl.org/id/ENSBTAT00000064708.2" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000054527.2", "url": "https://www.ensembl.org/id/ENSBTAP00000054527.2" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [ { "id": "bta:100299320", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?bta:100299320", "resource": "KEGG Pathway" } ], "orthologs": [ { "uniprot_canonical_ac": "F1M2T9-1", "protein_name": "Olfactory receptor family 10 subfamily D member 4B", "gene_name": "Or10d4b", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MTNHTMVTEFTLLGIPETEGLENVLLFFFATMYACALLGNFLILTAITTSPRLHTPMYFFLGNLSIFDLCFCSTTAPKMLSYLSGWGGGISFKGCVVQHFFYHCLGCTLCFLYTVMAYDRFVAICFPLRYTIIMNHRVCCALATGTWMSGCIHSTILTSLTFQLPYCGPSEVSYYFCDMPAVLLLACEDSSLAQRVGFTNVGLLSLICFFLIVVSYTRIGISISKIRSTEGRQRAFSTCSAHLTAIMCVYGPVIIIYLQPNPSPQLSAIIQILHNLVTPTINPLIYSLRNKDVKAALRHVFLKKCLSLEVNEHT", "length": 314 }, "evidence": [ { "id": "G3MY98", "url": "https://omabrowser.org/oma/group/G3MY98/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "Q7TRA9-1", "protein_name": "Olfactory receptor family 10 subfamily D member 4", "gene_name": "Or10d4", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MTNHTMVTEFTLLGIPETEGLENVLLFLFSTLYACALLGNLLLLTAVISSPQLHTPMYFFLGNLSIFDMGFCSTTAPKMLSYLSGQGGGISFQGCVVQHFFYHCLGCTECFLYTVMAYDRFVAICFPLRYTIIMNHRVCCVLATGTWMSGCVHATILTCLTFQLPYCGPSNVGYYFCDMPAVLPLACEDHSLAQRVGFTNVGLLSLICFFLILVSYTRIGISISKIRSTEGRQRAFSTCSAHLTAIICAYGPVIVIYLQPNPSPLLGAVIQILNNLVTPTINPLIYSLRNKDVKAALRHVFLKRSLSLESK", "length": 311 }, "evidence": [ { "id": "G3MY98", "url": "https://omabrowser.org/oma/group/G3MY98/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" } ], "go_annotation": { "categories": [ { "name": "Molecular Function", "total": 2, "go_terms": [ { "name": "G protein-coupled receptor activity", "id": "GO:0004930", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0004930", "evidence": [ { "database": "UniProtKB", "id": "G3MY98", "url": "https://www.uniprot.org/uniprotkb/G3MY98" } ], "pmid": "" }, { "name": "olfactory receptor activity", "id": "GO:0004984", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0004984", "evidence": [ { "database": "UniProtKB", "id": "G3MY98", "url": "https://www.uniprot.org/uniprotkb/G3MY98" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 1, "go_terms": [ { "name": "plasma membrane", "id": "GO:0005886", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005886", "evidence": [ { "database": "UniProtKB", "id": "G3MY98", "url": "https://www.uniprot.org/uniprotkb/G3MY98" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 1, "go_terms": [ { "name": "detection of chemical stimulus involved in sensory perception of smell", "id": "GO:0050911", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0050911", "evidence": [ { "database": "UniProtKB", "id": "G3MY98", "url": "https://www.uniprot.org/uniprotkb/G3MY98" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 3, "end_pos": 5, "annotation": "n_glycosylation_sequon" }, { "start_pos": 63, "end_pos": 65, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], 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Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 3, "end_pos": 5 }, { "start_pos": 63, "end_pos": 65 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", 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"field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ], "tool_support": { "graph_view": "yes" } }, { "uniprot_canonical_ac": "G3MYC0-1", "uniprot_ac": "G3MYC0", "uniprot_id": "G3MYC0_BOVIN", "mass": { "chemical_mass": 43501.0, "monoisotopic_mass": 43501.0 }, "refseq": { "ac": "NP_001421757", "name": "ankyrin repeat domain-containing protein 10 isoform 1", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001421757" }, "gene_names": [ { "name": "ANKRD10", "type": "recommended", "evidence": [ { "id": "G3MYC0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3MYC0" } ] }, { "name": "ANKRD10", "type": "synonym", "evidence": [ { "id": "NP_001421757", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001421757" } ] } ], "protein_names": [ { "name": "Ankyrin repeat domain 10", "type": "synonym", "evidence": [ { "id": "G3MYC0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3MYC0/entry#names_and_taxonomy" } ] }, { "name": "ankyrin repeat domain-containing protein 10 isoform 1", "type": "synonym", "evidence": [ { "id": "NP_001421757", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001421757" } ] } ], "function": [], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Bos taurus", "taxid": 9913, "evidence": [ { "database": "UniProtKB", "id": "G3MYC0", "url": "https://www.uniprot.org/uniprotkb/G3MYC0" } ], "common_name": "Bovine", "glygen_name": "Bovine", "reference_species": "Bos taurus [9913]" } ], "gene": [ { "name": "ANKRD10", "url": "https://www.uniprot.org/uniprotkb/G3MYC0", "locus": { "chromosome": "12", "start_pos": 85327078, "end_pos": 85359030, "strand": "+", "evidence": [ { "database": "Ensembl Gene", "id": "ENSBTAG00000004041", "url": "https://www.ensembl.org/id/ENSBTAG00000004041" } ] } } ], "crossref": [ { "id": "G3MYC0", "url": "https://alphafold.ebi.ac.uk/entry/G3MYC0", "database": "AlphaFoldDB", "categories": [] }, { "id": "ENSBTAG00000004041", "url": "https://bgee.org/?page=gene&gene_id=ENSBTAG00000004041", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "510084", "url": "https://www.ncbi.nlm.nih.gov/gene/510084", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR002110", "url": "https://www.ebi.ac.uk/interpro/entry/IPR002110", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR036770", "url": "https://www.ebi.ac.uk/interpro/entry/IPR036770", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR050776", "url": "https://www.ebi.ac.uk/interpro/entry/IPR050776", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "ILNGVHQ", "url": "https://omabrowser.org/oma/group/ILNGVHQ/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "G3MYC0", "url": "https://www.orthodb.org/?gene=G3MYC0", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR24201", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR24201", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR24201:SF12", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR24201:SF12", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF12796", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF12796", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF13637", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF13637", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "NP_001421757", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001421757", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "G3MYC0", "url": "https://www.uniprot.org/uniprotkb/G3MYC0", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "G3MYC0-1", "url": "https://www.uniprot.org/uniprotkb/G3MYC0-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MSAVGAGAGVEAGFSSEELLSLRFPLHRACRDGDLAALCSLLQQTPRAHLAAEDSFYGWTPVHWAAHFGKLECLIQLVRAGATLDVSTTRYAQTPAHIAAFGGHPQCLVWLIQAGASINKPDCEGETPIHKAARSGSLDCISALVANGAQVDLRNASGLTAADIAQTQGFQECTQFLLNLQNCHLTRFGHNGTLNGGHPSVFPSHVSVGTNRKRCLEDSEPFGMKKARPAAHSLDESMPLASGEVEDDPDKMHVDRELATDMKNSSSVSNTLTNGCVANGHLDFPSTAQPCGMESRSGQCSAGLNGVGTGLVPGLPFPSSQGSPGVNGTEEPERSTQVSPETCGSLHLNGSPSSCVASRPSWAEESLQYGHYHGFGDTAESIPELSSALEHASSVKAEQGYHSAVLGAMHLSHGS", "length": 415, "header": "tr|G3MYC0-1|G3MYC0_BOVIN Isoform 1 of Ankyrin repeat domain 10 OS=Bos taurus OX=9913 GN=ANKRD10 PE=4 SV=2 CANONICAL=G3MYC0-1" }, "isoforms": [ { "isoform_ac": "G3MYC0-1", "url": "https://www.uniprot.org/uniprotkb/G3MYC0/entry", "sequence": { "sequence": "MSAVGAGAGVEAGFSSEELLSLRFPLHRACRDGDLAALCSLLQQTPRAHLAAEDSFYGWTPVHWAAHFGKLECLIQLVRAGATLDVSTTRYAQTPAHIAAFGGHPQCLVWLIQAGASINKPDCEGETPIHKAARSGSLDCISALVANGAQVDLRNASGLTAADIAQTQGFQECTQFLLNLQNCHLTRFGHNGTLNGGHPSVFPSHVSVGTNRKRCLEDSEPFGMKKARPAAHSLDESMPLASGEVEDDPDKMHVDRELATDMKNSSSVSNTLTNGCVANGHLDFPSTAQPCGMESRSGQCSAGLNGVGTGLVPGLPFPSSQGSPGVNGTEEPERSTQVSPETCGSLHLNGSPSSCVASRPSWAEESLQYGHYHGFGDTAESIPELSSALEHASSVKAEQGYHSAVLGAMHLSHGS", "length": 415, "header": "tr|G3MYC0-1|G3MYC0_BOVIN Isoform 1 of Ankyrin repeat domain 10 OS=Bos taurus OX=9913 GN=ANKRD10 PE=4 SV=2 CANONICAL=G3MYC0-1" }, "locus": { "chromosome": "12", "start_pos": 85358849, "end_pos": 85328164, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000063159.3", "url": "https://www.ensembl.org/id/ENSBTAT00000063159.3" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000054552.2", "url": "https://www.ensembl.org/id/ENSBTAP00000054552.2" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [], "orthologs": [ { "uniprot_canonical_ac": "A0A287AKA9-1", "protein_name": "Ankyrin repeat domain 10", "gene_name": "ANKRD10", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MSAAGAGAGVEAGFSSEELLSLRFPLHRACRDGDLAALCSLLQQTPRAHLAAEDSFYGWTPVHWAAHFGKLECLMQLVRAGATLDVSTTRYAQTPAHIAAFGGHPQCLVWLIQAGASINKPDCEGETPIHKAARSGSLDCVSALVANGAHVDLRNASGLTAADIAQTQGFQECTQFLLNLQNCRLNRFYSNGTLNGGHPGVFPNHVSVGTNRKRCLEDPEPFGVKKARTAAQSSDDSMPLLNGEVEDEADKMHVDREFAVLTDVKSSSSVSSTLTNGGVRNGHLDFPSTTQLSGTESRSDQCLAGPGGIGSGLAPAPPFPSSQGSLCVHGTEEPAKSSGVNPEMCGSLHLNGSPSSCVASRPSWAEDLGENLRYGHYHGFGDTAESLPELSSVVEHSSSVKVEQGYDSAVLGTMHLFHGS", "length": 420 }, "evidence": [ { "id": "G3MYC0", "url": "https://omabrowser.org/oma/group/G3MYC0/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "Q99LW0-1", "protein_name": "Ankyrin repeat domain-containing protein 10", "gene_name": "Ankrd10", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MSAGAGAAVEAGFSSEELLSLRFPLHRACRDGDLVALCSLLPHTPRAHLAAEDSFYGWTPVHWAAHFGKLECLMQLVRAGASLNVSTTRYAQTPAHIAAFGGHPQCLVWLIQAGANINKPDCEGETPIHKAARSGSLECITALVGSGAHTDLRNASGLTAADIAQTQGFQECTQFLLSLQNHQMSRFCHNGTLSGGHESILPTHVSLGTNRKRCLEDSESLGVKKARTRVPSLDHAMPLANGEAEDDADRMHVDRECAAVSDMKNSSSVLNTLTNGSVVNGHLDFPCANQLNGMESRSHPCLTGSNGVSNGQPLSSGQASVSANGTEEPEKTMGINPEMCGSLHLNGSPSSCVASRPSWVGDIGESLHYGHYHGFGDTAESIPELSSVLEHTSCVRVEQRYDSAVLGAMQLHHGS", "length": 415 }, "evidence": [ { "id": "G3MYC0", "url": "https://omabrowser.org/oma/group/G3MYC0/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q9NXR5-1", "protein_name": "Ankyrin repeat domain-containing protein 10", "gene_name": "ANKRD10", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": 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[], "keywords": [], "publication": [], "pathway": [ { "id": "bta:540449", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?bta:540449", "resource": "KEGG Pathway" } ], "orthologs": [ { "uniprot_canonical_ac": "A0A8V0YSG0-1", "protein_name": "Family with sequence similarity 181 member A", "gene_name": "FAM181A", "tax_id": 9031, "organism": "Gallus gallus", "sequence": { "sequence": "MASDSEVKTLLNFVNLASSDIKAALDKSAPCRRSVDHRKYLQKQLKRFSQKYSRVPRCHPTKPPECGPRRGAEDRARSCQPEVPDPGPHSGAATEKVLQAAEAEESLMREQAVPEQNPETNRPDQVPMRKRQLPASFWEEPRPPQSLPAGGFPPGPEGLPVPRDPPPFEGKKSKRSQDTIGPESHEPALNAGEKDPTGVLSGRVGAWTCCPFPCPGPAVYQPPGTLPPSPFPGLGLWRKGTATLPAEAQPFCKDAEGTGQKLYRPVVLKPIPTKPTIPPPIFNVFGYL", "length": 288 }, "evidence": [ { "id": "G3MYF5", "url": "https://omabrowser.org/oma/group/G3MYF5/", "database": "OMA" } ], "glygen_name": "Chicken", "common_name": "Chicken" }, { "uniprot_canonical_ac": "G3HU80-1", "protein_name": "Protein FAM181A", "gene_name": "Fam181a", "tax_id": 10029, "organism": "Cricetulus griseus", "sequence": { "sequence": "MAADSDVKMLLNFVNLASSDIKAALDKSAPCRRSVDHRKYLQKQLKRFSQKYSRLPRGLPGRVTEPHLQRGPEERPGQLPLHPCPESNPGGGGGYKEKALGTPFREECLSKEQSFQGLNPEAARPGQVPMRKRQLPASFWEEPRPTLSYPMGLEVGLAPREASLYENKKNCKGLESLGPETAPAPLPMSPRVLADMEPLKMSGVSLVGSLDAWSYCPFQYHGQPIFPSLPGVLPQGPVPSLGLWRKSPASPVELAHFCKDVDSSGPKVYRPVVLKPIPTKPAMPPPIFNVFGYL", "length": 294 }, "evidence": [ { "id": "G3MYF5", "url": "https://omabrowser.org/oma/group/G3MYF5/", "database": "OMA" } ], "glygen_name": "Hamster", "common_name": "Chinese hamster" }, { "uniprot_canonical_ac": "J3QNB7-1", "protein_name": "Family with sequence similarity 181, member A", "gene_name": "Fam181a", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MAADSDVKMLLNFVNLASSDIKAALDKSAPCRRSVDHRKYLQKQLKRFSQKYSRLPRGLPGRVAEPHLQRGPEERPGRPPLHPCPQSSPGGGGSCTEKALGTPFREECLSKDQGFRGLNPEAARPGQVPMRKRQLPASFWEEPRPTLSYPMGLEVGLAPREASLYENKKNCKGLESLGPETAPLPMSPRVLADTEPLKMSGVSLVGSLDAWSYCPFQSHGQPIFPGLPGVLPQGPVPSLGLWRRSLASPVDLAHFCKGVDTPGPKVYRPVVLKPIPTKPAMPPPIFNVFGYL", "length": 292 }, "evidence": [ { "id": "G3MYF5", "url": "https://omabrowser.org/oma/group/G3MYF5/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "M0RC29-1", "protein_name": "Family with sequence similarity 181, member A", "gene_name": "Fam181a", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MQAARVLRGAGRSLTWWPQSLSPAECTKSLEHEGWYLLLPVKVCPGLSSELPAPSRTHTLHGKPCTVPVVMAADSDVKMLLNFVNLASSDIKAALDKSAPCRRSVDHRKYLQKQLKRFSQKYSRLPRGLPGRVTEPHLQRGPEERPGRLPLHPCPQASTGGGGSCTEKALGTPFREECLSKEQSFRGLNPEATRPGQVPMRKRQLPASFWEEPRPTLSYPMGLEVGLAPREASLYENKKNCKGLESLGPETAPLPMSPRVLTDTESLKMSGVSLVGSLDAWSYCPFQYHGQPIFPGLPGVLPQGPVPSVGLWRKSPASPVELAHFCKDVDTPGPKVYRPVVLKPIPTKPAMPPPIFNVFGYL", "length": 362 }, "evidence": [ { "id": "G3MYF5", "url": "https://omabrowser.org/oma/group/G3MYF5/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "Q8N9Y4-1", "protein_name": "Protein FAM181A", "gene_name": "FAM181A", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": 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"https://www.ncbi.nlm.nih.gov/protein/XP_005215331", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "G3MYK2", "url": "https://www.uniprot.org/uniprotkb/G3MYK2", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "G3MYK2-1", "url": "https://www.uniprot.org/uniprotkb/G3MYK2-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MELTAPTSGRGPDPRLGRLLGNLDAQSLRSCTSQEGGFQQVTVTHWKIQTAEAAQAGSKSEGSPLLSPDLLLLQRELIEGEAPQHEACGSFPFNPGLARHQASHAGEKAHRCDECGKGFSQSSHLVEHQHAHGGERLYVCNACGKDFVLYTDLLEHQKVHTGERPFKCAQCGKAFCHSSDLIRHQRVHTRERPFECKECGKGFSQSSLLIRHQRIHTGERPYECNECGKAFIRSSSLIRHFQVHTEVRQYECQDCGKAFRHRSDLIEHQRIHTGERPFECNECGKAFIRSSKLIQHQRIHTGERPYVCNECGKRFSQTSNFTQHQRIHTGEKLYECNECGKAFFLSSYLIRHQKIHTGERVYECKECGKAFLQKAHLTEHQKIHSGDRPFECKDCGKAFIQSSKLLLHQIIHTGEKPYVCSYCGKGFIQRSNFLQHQKIHTEEKLYECSQYGKEFTPPPDFKSSQEAPQEGLPLSQTAVHFGETCGGLGGHTDF", "length": 494, "header": "tr|G3MYK2-1|G3MYK2_BOVIN Isoform 1 of Zinc finger protein 623 OS=Bos taurus OX=9913 GN=ZNF623 PE=3 SV=2 CANONICAL=G3MYK2-1" }, "isoforms": [ { "isoform_ac": "G3MYK2-1", "url": "https://www.uniprot.org/uniprotkb/G3MYK2/entry", "sequence": { "sequence": "MELTAPTSGRGPDPRLGRLLGNLDAQSLRSCTSQEGGFQQVTVTHWKIQTAEAAQAGSKSEGSPLLSPDLLLLQRELIEGEAPQHEACGSFPFNPGLARHQASHAGEKAHRCDECGKGFSQSSHLVEHQHAHGGERLYVCNACGKDFVLYTDLLEHQKVHTGERPFKCAQCGKAFCHSSDLIRHQRVHTRERPFECKECGKGFSQSSLLIRHQRIHTGERPYECNECGKAFIRSSSLIRHFQVHTEVRQYECQDCGKAFRHRSDLIEHQRIHTGERPFECNECGKAFIRSSKLIQHQRIHTGERPYVCNECGKRFSQTSNFTQHQRIHTGEKLYECNECGKAFFLSSYLIRHQKIHTGERVYECKECGKAFLQKAHLTEHQKIHSGDRPFECKDCGKAFIQSSKLLLHQIIHTGEKPYVCSYCGKGFIQRSNFLQHQKIHTEEKLYECSQYGKEFTPPPDFKSSQEAPQEGLPLSQTAVHFGETCGGLGGHTDF", "length": 494, "header": "tr|G3MYK2-1|G3MYK2_BOVIN Isoform 1 of Zinc finger protein 623 OS=Bos taurus OX=9913 GN=ZNF623 PE=3 SV=2 CANONICAL=G3MYK2-1" }, "locus": { "chromosome": "14", "start_pos": 1073361, "end_pos": 1071880, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000129571.2", "url": "https://www.ensembl.org/id/ENSBTAT00000129571.2" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000101367.1", "url": "https://www.ensembl.org/id/ENSBTAP00000101367.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [ { "id": "bta:540256", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?bta:540256", "resource": "KEGG Pathway" } ], "orthologs": [ { "uniprot_canonical_ac": "A0A8C2LRG9-1", "protein_name": "Zinc finger protein 623", "gene_name": "Znf623", "tax_id": 10029, "organism": "Cricetulus griseus", "sequence": { "sequence": "MMSDKLTVLEPSVSEPGEFQEDRLVQLLGNPERKIIESSPSQEGSLKQMTVTRWKIQTGETAQMCSKSGRNPTLNSNLLILQRELIEGETHSCGIGSKSFSFNSNVVPHQISHTGEKPYQCDRCGKAFSQNSLLTEHQRVHTGDRLYVCNVCGKDFIHYTNLVEHQHVHTDEKPFKCAQCGKAFCHSSDLLRHQRVHTRERPFECKECGKGFSQSSLLIRHQRIHTGERPYECNECGKSFIRSSSLIRHYQIHTEVKQYECRDCGKAFRHRSDLIEHQRIHTGERPFECHECGKAFIRSSKLIQHQRIHTGERPYVCNECGKRFSQTSNFTQHQRIHTGEKLYECDECGKAFFLSSYLIRHQKIHTGERVYECKECGKAFLQKAHLTEHQKIHTGDRPFECKDCGKAFIQSSKLLLHQIVHTGEKPYVCSYCGKGFIQRSNFLQHQKVHTEEKLYKYSQHGKDLTPPPDLVHQEDLSLSETSIHLGERATDQECHADNL", "length": 499 }, "evidence": [ { "id": "G3MYK2", "url": "https://omabrowser.org/oma/group/G3MYK2/", "database": "OMA" } ], "glygen_name": "Hamster", "common_name": "Chinese hamster" }, { "uniprot_canonical_ac": "D3ZBN5-1", "protein_name": "Zinc finger protein 623", "gene_name": "Zfp623", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MMSDKLTVLEPSVSESREFHEDRLAQLLENPETQSLESPSCQDGGFTQMTVAHWKIQTGDTAPVCSKSGRNPILDSNLLILQRELIEGETRSCGVGGKNFPFNSDVDPHQVSHSGEKSYKCDHCGKGFSQTSLLTEHQRVHTRDRLCVCNVCGKDFIHYANLMEHQLVHTGEKPFKCAQCGKAFCHSSDLLRHQRVHTRERPFECKECGKGFSQSSLLIRHQRIHTGERPYECNECGKSFIRSSSLIRHYQIHTEVKQYECRDCGKAFRHRSDLIEHQRIHTGERPFECHECGKAFIRSSKLIQHQRIHTGERPYVCNECGKRFSQTSNFTQHQRIHTGEKLYECNECGKAFFLSSYLIRHQKIHTGERVYECKECGKAFLQKAHLTEHQKIHTGDRPFECKDCGKAFIQSSKLLLHQIVHTGEKPYVCSYCGKGFIQRSNFLQHQKMHTEEKLYKYSEHGKDLAPPPDLVPQEDLSLSETSVHLGETATDQERCGENF", "length": 499 }, "evidence": [ { "id": "G3MYK2", "url": "https://omabrowser.org/oma/group/G3MYK2/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "O75123-1", "protein_name": "Zinc finger protein 623", "gene_name": "ZNF623", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MILLSFVSDSNVGTGEKKVTEAWISEDENSHRTTSDRLTVMELPSPESEEVHEPRLGELLGNPEGQSLGSSPSQDRGCKQVTVTHWKIQTGETAQVCTKSGRNHILNSDLLLLQRELIEGEANPCDICGKTFTFNSDLVRHRISHAGEKPYTCDQCGKGFGQSSHLMEHQRIHTGERLYVCNVCGKDFIHYSGLIEHQRVHSGEKPFKCAQCGKAFCHSSDLIRHQRVHTRERPFECKECGKGFSQSSLLIRHQRIHTGERPYECNECGKSFIRSSSLIRHYQIHTEVKQYECKECGKAFRHRSDLIEHQRIHTGERPFECNECGKAFIRSSKLIQHQRIHTGERPYVCNECGKRFSQTSNFTQHQRIHTGEKLYECNECGKAFFLSSYLIRHQKIHTGERVYECKECGKAFLQKAHLTEHQKIHSGDRPFECKDCGKAFIQSSKLLLHQIIHTGEKPYVCSYCGKGFIQRSNFLQHQKIHTEEKLYECSQYGRDFNSTTNVKNNQRVHQEGLSLSKAPIHLGERSVDKGEHTGNL", "length": 536 }, "evidence": [ { "id": "G3MYK2", "url": "https://omabrowser.org/oma/group/G3MYK2/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" } ], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 2, "go_terms": [ { "name": "nucleus", "id": "GO:0005634", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005634", "evidence": [ { "database": "UniProtKB", "id": "G3MYK2", "url": "https://www.uniprot.org/uniprotkb/G3MYK2" } ], "pmid": "" }, { "name": "nucleoplasm", "id": "GO:0005654", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005654", "evidence": [ { "database": "UniProtKB", "id": "G3MYK2", "url": "https://www.uniprot.org/uniprotkb/G3MYK2" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 2, "go_terms": [ { "name": "DNA-templated transcription", "id": "GO:0006351", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006351", "evidence": [ { "database": "UniProtKB", "id": "G3MYK2", "url": "https://www.uniprot.org/uniprotkb/G3MYK2" } ], "pmid": "" }, { "name": "regulation of transcription by RNA polymerase II", "id": "GO:0006357", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006357", "evidence": [ { "database": "UniProtKB", "id": "G3MYK2", "url": "https://www.uniprot.org/uniprotkb/G3MYK2" } ], "pmid": "" } ] }, { "name": "Molecular Function", "total": 3, "go_terms": [ { "name": "zinc ion binding", "id": "GO:0008270", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008270", "evidence": [ { "database": "UniProtKB", "id": "G3MYK2", "url": "https://www.uniprot.org/uniprotkb/G3MYK2" } ], "pmid": "" }, { "name": "RNA polymerase II cis-regulatory region sequence-specific DNA binding", "id": "GO:0000978", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000978", "evidence": [ { "database": "UniProtKB", "id": "G3MYK2", "url": "https://www.uniprot.org/uniprotkb/G3MYK2" } ], "pmid": "" }, { "name": "DNA-binding transcription factor activity, RNA polymerase II-specific", "id": "GO:0000981", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000981", "evidence": [ { "database": "UniProtKB", "id": "G3MYK2", "url": "https://www.uniprot.org/uniprotkb/G3MYK2" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 320, "end_pos": 322, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "G3MYK2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3MYK2" }, { "id": "PS50157", "database": "PROSITE", "url": "https://prosite.expasy.org/PS50157" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "C2H2-type", "eco_id": "ECO_0000259", "start_pos": 110, "end_pos": 137, "start_aa": "His", "end_aa": "Leu", "glycosite_overlap": [] } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "homologset.oma", "label": "OMA Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 320, "end_pos": 322 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ], "tool_support": { "graph_view": "yes" } }, { "uniprot_canonical_ac": "G3MYM5-1", "uniprot_ac": "G3MYM5", "uniprot_id": "G3MYM5_BOVIN", "mass": { "chemical_mass": 15288.0, "monoisotopic_mass": 15288.0 }, "refseq": {}, "gene_names": [], "protein_names": [ { "name": "Immunoglobulin domain-containing protein", "type": "recommended", "evidence": [ { "id": "G3MYM5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3MYM5/entry#names_and_taxonomy" } ] } ], "function": [], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Bos taurus", "taxid": 9913, "evidence": [ { "database": "UniProtKB", "id": "G3MYM5", "url": "https://www.uniprot.org/uniprotkb/G3MYM5" } ], "common_name": "Bovine", "glygen_name": "Bovine", "reference_species": "Bos taurus [9913]" } ], "gene": [ { "name": "", "url": "https://www.uniprot.org/uniprotkb/G3MYM5", "locus": {} } ], "crossref": [ { "id": "G3MYM5", "url": "https://alphafold.ebi.ac.uk/entry/G3MYM5", "database": "AlphaFoldDB", "categories": [] }, { "id": "ENSBTAG00000052008", "url": "https://bgee.org/?page=gene&gene_id=ENSBTAG00000052008", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "IPR003599", "url": "https://www.ebi.ac.uk/interpro/entry/IPR003599", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR013106", "url": "https://www.ebi.ac.uk/interpro/entry/IPR013106", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR013783", "url": "https://www.ebi.ac.uk/interpro/entry/IPR013783", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR036179", "url": "https://www.ebi.ac.uk/interpro/entry/IPR036179", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR050413", "url": "https://www.ebi.ac.uk/interpro/entry/IPR050413", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "PRNQITR", "url": "https://omabrowser.org/oma/group/PRNQITR/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "PTHR23268", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR23268", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR23268:SF19", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR23268:SF19", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF07686", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF07686", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "G3MYM5", "url": "https://www.uniprot.org/uniprotkb/G3MYM5", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "G3MYM5-1", "url": "https://www.uniprot.org/uniprotkb/G3MYM5-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MGPRLLCCVTLCLLGAGAVHAGVTQDPRFQVVRRGQSGTLKCTQDLGHDRMYWYRQDLGHGLRPIHYSAGVSTSEPRDVPDGYSVSRSSTENFPLMLESANHSQTSVYFCASSYSTALQGHLLSVEKDKGPTCRILALVT", "length": 140, "header": "tr|G3MYM5-1|G3MYM5_BOVIN Isoform 1 of Immunoglobulin domain-containing protein OS=Bos taurus OX=9913 GN= PE=4 SV=2 CANONICAL=G3MYM5-1" }, "isoforms": [ { "isoform_ac": "G3MYM5-1", "url": "https://www.uniprot.org/uniprotkb/G3MYM5/entry", "sequence": { "sequence": "MGPRLLCCVTLCLLGAGAVHAGVTQDPRFQVVRRGQSGTLKCTQDLGHDRMYWYRQDLGHGLRPIHYSAGVSTSEPRDVPDGYSVSRSSTENFPLMLESANHSQTSVYFCASSYSTALQGHLLSVEKDKGPTCRILALVT", "length": 140, "header": "tr|G3MYM5-1|G3MYM5_BOVIN Isoform 1 of Immunoglobulin domain-containing protein OS=Bos taurus OX=9913 GN= PE=4 SV=2 CANONICAL=G3MYM5-1" }, "locus": { "chromosome": "4", "start_pos": 105623334, "end_pos": 105613007, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000064293.3", "url": "https://www.ensembl.org/id/ENSBTAT00000064293.3" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000054661.2", "url": "https://www.ensembl.org/id/ENSBTAP00000054661.2" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [], "orthologs": [ { "uniprot_canonical_ac": "A0A1B0GX49-1", "protein_name": "T cell receptor beta variable 6-4", "gene_name": "TRBV6-4", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MSIRLLCCVAFSLLWAGPVTAGITQAPTSQILAAGRSMTLRCTQDMRHNAMYWYRQDLGLGLRLIHYSNTAGTTGKGEVPDGYSVSRANTDDFPLTLASAVPSQTSVYFCASSD", "length": 114 }, "evidence": [ { "id": "G3MYM5", "url": "https://omabrowser.org/oma/group/G3MYM5/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" } ], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 2, "go_terms": [ { "name": "plasma membrane", "id": "GO:0005886", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005886", "evidence": [ { "database": "UniProtKB", "id": "G3MYM5", "url": "https://www.uniprot.org/uniprotkb/G3MYM5" } ], "pmid": "" }, { "name": "T cell receptor complex", "id": "GO:0042101", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0042101", "evidence": [ { "database": "UniProtKB", "id": "G3MYM5", "url": "https://www.uniprot.org/uniprotkb/G3MYM5" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 2, "go_terms": [ { "name": "cell surface receptor signaling pathway", "id": "GO:0007166", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007166", "evidence": [ { "database": "UniProtKB", "id": "G3MYM5", "url": "https://www.uniprot.org/uniprotkb/G3MYM5" } ], "pmid": "" }, { "name": "immune system process", "id": "GO:0002376", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0002376", "evidence": [ { "database": "UniProtKB", "id": "G3MYM5", "url": "https://www.uniprot.org/uniprotkb/G3MYM5" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 101, "end_pos": 103, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [ { "pdb_id": "AF-G3MYM5-F1", "pdb_chain": "global", "start_pos": 1, "end_pos": 140, "overlap": "1.0", "method": "AlphaFold", "type": "alphafold", "resolution": -1.0, "url": "https://data.glygen.org/ln2downloads/pdb/current/AF-G3MYM5-F1.pdb", "url_external": "https://alphafold.ebi.ac.uk/entry/G3MYM5" } ], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "G3MYM5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3MYM5" }, { "id": "SM00409", "database": "SMART", "url": "http://smart.embl.de/smart/do_annotation.pl?DOMAIN=SM00409" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "Immunoglobulin", "eco_id": "ECO_0000259", "start_pos": 27, "end_pos": 126, "start_aa": "Pro", "end_aa": "Glu", "glycosite_overlap": [] } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "homologset.oma", "label": "OMA Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 101, "end_pos": 103 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", 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"table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ], "tool_support": { "graph_view": "yes" } }, { "uniprot_canonical_ac": "G3MYM8-1", "uniprot_ac": "G3MYM8", "uniprot_id": "G3MYM8_BOVIN", "mass": { "chemical_mass": 158171.0, "monoisotopic_mass": 158171.0 }, "refseq": { "ac": "XP_024831762", "name": "proteoglycan 4 isoform X1", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_024831762" }, "gene_names": [ { "name": "PRG4", "type": "recommended", "evidence": [ { "id": "G3MYM8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3MYM8" } ] }, { "name": "MSF", "type": "synonym", "evidence": [ { "id": "XP_024831762", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_024831762" } ] }, { "name": "PRG4", "type": "synonym", "evidence": [ { "id": "XP_024831762", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_024831762" } ] }, { "name": "lubricin", "type": "synonym", 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"id": "PTHR22917", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR22917", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR22917:SF1", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR22917:SF1", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00045", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00045", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF01033", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF01033", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "XP_024831762", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_024831762", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "F1MDS0", "url": "https://www.uniprot.org/uniprotkb/F1MDS0", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "F1MDS0-1", "url": "https://www.uniprot.org/uniprotkb/F1MDS0-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "G3MYM8", "url": "https://www.uniprot.org/uniprotkb/G3MYM8", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "G3MYM8-1", "url": "https://www.uniprot.org/uniprotkb/G3MYM8-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MEWKILPIYLLLFSVFLIQQASSQDLSSCAGRCGEGYSRDAICNCDYNCQHYTECCPDFKKECTVELSCKGRCFETFARGRECDCDSDCKKYGKCCSDYGTFCEAVKDKKKRTPKNKPTPEPPVIDEDGSGLDNGDFKLTPTPNIPTTQRNKVTTTPKITTVKPTLPKPSLPPNSDTTKEIPSTVNRETTVETKETSTTNKPTSTSAKEKTTSAKETRTAENTSTKGLAPTPEVPAISTPKAETITRSPTPTTPKEPAPTTKEPALTTTTKEPASTTPKKPAPTTPKETAPTTKEPEPTTKEPEPTTPKQPAPTTPKEPAPTTPKETAPTTKEPEPTTPKQPAPTTPKQPAPTTSKETAPTTKEPAPTTPKEPAPTTPKEPAPTTPKEPAPTTKEPEPTTPKQPAPTTPKEPAPTTPKETAPTPKEPAPTTPKEPAPTTPKEPAPTTPKEPAPTTPKEPAPTTKEPESTTKEPEPTTKEPEPTTPKQPAPTTPKEPAPTTPKETAPTTKEPAPTTPKQPAPTTPKQPAPTTPKEPAPTTPKEPAPTTKEPAPTTKEPEPTTKEPAPTTTPKEPAPTTPKEPAPTTKEPEPTTLKQPAPTTPKEPAPTTPKEPAPTTPKEPTPTTPKEPAPTTPKEPAPTTPKEPTPTTPKEPAPTTTPKEPAPTTKEPEPTTKEPAPTTTTKEPAPTIPKEPAPTTPKEPAPTTHKEPTPTTTPKEPAPTSPKEPAPTSPKEPAPTSPKEPAPTTTPKEPAPTDPKEPAPAEPKEPAPTSSKEPAPTTTTKEPAPTTTPKEPAPTDPKEPAPAEPKEPAPTSPKEPAPTTTTKEPAPAEPKEPAPTSPKEPAPTTTTKEPAPAEPKEPAPTSPKEPAPTTTTKEPAPTTTPKEPAPTDPKEPAPAEPKEPAPAEPKEPTPNSPETLAPSSPDIPAPTTSEASTSTTTVEPSTTLKSPAESTPQPPIEPTPKALENSPKEPAVPTIKGPKVNKPEITTTVKDKSTEKDIYSTPEITTAVAKIITEAATKTEKTTESKIPSTTTDVTSTTTKDTTSSKITPKATLAPKVMTATKKTTEKTKNKPEKTTAVPKGRATNSQVTTPKPQKPTKAPKKPTSTKKPRTPRVRKPKTTPTPPKTTTSAMPEPTPTSLPEAMLQTTTRPTPTPNSEIIDVNPENEDGDAAEGEKPHMIFRPPVLTPIVIPGTEIIVRGPSQGFGINPMFSDETNLCNGRPVDGLTTLRNGTLVAFRGHYFWMLTPFTPPPPPRRITEVWGIPSPIDTVFTRCNCEGKTFFFKGSQYWRFTNDIKDAGYPKLISKGFGGLNGKIVAALSIAQYKSRPESVYFFKRGGSVQQYTYKQEPTQKCTGRRPAINYSVYGETAQVRRRRFERAIGPSQVHTIRIHYTPVRVPYQDKGFLHNEVKVSTLWRGLPNVVTSAISLPNIRKPDGYDYYALSKDQYYNIDVPSRTARAITTRSGQTLSNTWYNCP", 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"length": 1195, "header": "tr|F1MDS0-1|F1MDS0_BOVIN Computationally mapped isoform of Proteoglycan 4 OS=Bos taurus OX=9913 GN=PRG4 PE=4 SV=3 CANONICAL=G3MYM8-1" }, "locus": { "chromosome": "16", "start_pos": 67397829, "end_pos": 67381620, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000015839.5", "url": "https://www.ensembl.org/id/ENSBTAT00000015839.5" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000015839.5", "url": "https://www.ensembl.org/id/ENSBTAP00000015839.5" } ] } }, { "isoform_ac": "G3MYM8-1", "url": "https://www.uniprot.org/uniprotkb/G3MYM8/entry", "sequence": { "sequence": 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"ENSBTAG00000048288", "url": "https://www.ensembl.org/id/ENSBTAG00000048288" } ] } } ], "crossref": [ { "id": "G3MYQ2", "url": "https://alphafold.ebi.ac.uk/entry/G3MYQ2", "database": "AlphaFoldDB", "categories": [] }, { "id": "ENSBTAG00000048288", "url": "https://bgee.org/?page=gene&gene_id=ENSBTAG00000048288", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "G3MYQ2", "url": "https://www.uniprot.org/uniprotkb/G3MYQ2", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "G3MYQ2-1", "url": "https://www.uniprot.org/uniprotkb/G3MYQ2-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MKLLFPIFASLMLQWQVNTEYFGLRRCLMGLGRCKEHCNMDEKELDKCKKKTCCIRSKVVQLIKNYIQNEMLHMLKEDSQEVLKITKNFSVMMQTEHHNLSVLPKIKSANAFAKINTIIIPNATIVNSATTNPVNSGKIIHTATSTRKRRDLGTDSPPPAPPPSYILPTALELEADEQG", "length": 179, "header": "tr|G3MYQ2-1|G3MYQ2_BOVIN Isoform 1 of Defensin beta 129 OS=Bos taurus OX=9913 GN=DEFB129 PE=4 SV=3 CANONICAL=G3MYQ2-1" }, "isoforms": [ { 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"end_pos": 124 }, { "start_pos": 88, "end_pos": 90 }, { "start_pos": 99, "end_pos": 101 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ], "tool_support": { "graph_view": "yes" } }, { "uniprot_canonical_ac": "G3MYT4-1", "uniprot_ac": "G3MYT4", "uniprot_id": "G3MYT4_BOVIN", "mass": { "chemical_mass": 45624.0, "monoisotopic_mass": 45624.0 }, "refseq": { "ac": "XP_024852694", "name": "trophoblast glycoprotein", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_024852694" }, "gene_names": [ { "name": "TPBG", "type": "recommended", "evidence": [ { "id": "G3MYT4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3MYT4" } ] }, { "name": "TPBG", "type": "synonym", "evidence": [ { "id": "XP_024852694", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_024852694" } ] } ], "protein_names": [ { "name": "Trophoblast glycoprotein", "type": "synonym", "evidence": [ { "id": "G3MYT4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3MYT4/entry#names_and_taxonomy" } ] }, { "name": "trophoblast glycoprotein", "type": "synonym", "evidence": [ { "id": "XP_024852694", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_024852694" } ] } ], "function": [], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Bos taurus", "taxid": 9913, "evidence": [ { "database": "UniProtKB", "id": "G3MYT4", "url": "https://www.uniprot.org/uniprotkb/G3MYT4" } ], "common_name": "Bovine", "glygen_name": "Bovine", "reference_species": "Bos taurus [9913]" } ], "gene": [ { "name": "TPBG", "url": "https://www.uniprot.org/uniprotkb/G3MYT4", "locus": { "chromosome": "9", "start_pos": 22194150, "end_pos": 22188929, "strand": "-", "evidence": [ { "database": "Ensembl Gene", "id": "ENSBTAG00000039477", "url": "https://www.ensembl.org/id/ENSBTAG00000039477" } ] } } ], "crossref": [ { "id": "ENSBTAG00000039477", "url": "https://bgee.org/?page=gene&gene_id=ENSBTAG00000039477", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "540358", "url": "https://www.ncbi.nlm.nih.gov/gene/540358", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR000372", "url": "https://www.ebi.ac.uk/interpro/entry/IPR000372", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR000483", "url": "https://www.ebi.ac.uk/interpro/entry/IPR000483", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR001611", "url": "https://www.ebi.ac.uk/interpro/entry/IPR001611", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR003591", "url": "https://www.ebi.ac.uk/interpro/entry/IPR003591", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR032675", "url": "https://www.ebi.ac.uk/interpro/entry/IPR032675", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR052286", "url": "https://www.ebi.ac.uk/interpro/entry/IPR052286", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "bta:540358", "url": "https://www.genome.jp/dbget-bin/www_bget?bta:540358", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "FVKPSDM", "url": "https://omabrowser.org/oma/group/FVKPSDM/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "G3MYT4", "url": "https://www.orthodb.org/?gene=G3MYT4", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR24364", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR24364", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR24364:SF17", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR24364:SF17", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF01462", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF01462", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF01463", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF01463", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF13855", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF13855", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "XP_024852694", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_024852694", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "G3MYT4", "url": "https://www.uniprot.org/uniprotkb/G3MYT4", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "G3MYT4-1", "url": "https://www.uniprot.org/uniprotkb/G3MYT4-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MPGGCSRGPAAGDGRLRLARLALVLLGWVSSTSLPSSASSSTSSASLPAPAASGQPALPGRCPAPCECSEAARTVKCVNRNLTEVPADLPPYVRNLFLTGNQLAVLPAGAFARRPPLADLAALNLSGNRLKEVDAGAFEHLPGLRQLDLSHNPLADLSPFAFSGSNASVATPSPLAELILNRLELPAAERQNLSLEGMVAAALRAGHALRGLRRLELASNQLLYLPHDVLAHLPGLRHLDLRNNSLVGLTHVSFRNLTHLESLHLEDNALKVLRNGTLAELQSLPHVRVFLDDNPWVCDCHMVDMVAWLKETEVVQGKGRLTCAFPEKMRHRVLLELNSSDLDCDPILPPSLQTSYVFLGIVLALIGAIFLLVLYLNRKGIKKWMHNIRDACRDHMEGYHYRYEINADPRLTNLSSNSDV", "length": 420, "header": "tr|G3MYT4-1|G3MYT4_BOVIN Isoform 1 of Trophoblast glycoprotein OS=Bos taurus OX=9913 GN=TPBG PE=4 SV=1 CANONICAL=G3MYT4-1" }, "isoforms": [ { "isoform_ac": "G3MYT4-1", "url": "https://www.uniprot.org/uniprotkb/G3MYT4/entry", "sequence": { "sequence": "MPGGCSRGPAAGDGRLRLARLALVLLGWVSSTSLPSSASSSTSSASLPAPAASGQPALPGRCPAPCECSEAARTVKCVNRNLTEVPADLPPYVRNLFLTGNQLAVLPAGAFARRPPLADLAALNLSGNRLKEVDAGAFEHLPGLRQLDLSHNPLADLSPFAFSGSNASVATPSPLAELILNRLELPAAERQNLSLEGMVAAALRAGHALRGLRRLELASNQLLYLPHDVLAHLPGLRHLDLRNNSLVGLTHVSFRNLTHLESLHLEDNALKVLRNGTLAELQSLPHVRVFLDDNPWVCDCHMVDMVAWLKETEVVQGKGRLTCAFPEKMRHRVLLELNSSDLDCDPILPPSLQTSYVFLGIVLALIGAIFLLVLYLNRKGIKKWMHNIRDACRDHMEGYHYRYEINADPRLTNLSSNSDV", "length": 420, "header": "tr|G3MYT4-1|G3MYT4_BOVIN Isoform 1 of Trophoblast glycoprotein OS=Bos taurus OX=9913 GN=TPBG PE=4 SV=1 CANONICAL=G3MYT4-1" }, "locus": { "chromosome": "9", "start_pos": 22192438, "end_pos": 22191179, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000089512.1", "url": "https://www.ensembl.org/id/ENSBTAT00000089512.1" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000094402.1", "url": "https://www.ensembl.org/id/ENSBTAP00000094402.1" } ] } } ], "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "other", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 171, "start_aa": "Thr", "end_pos": 171, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr171", "evidence": [ { "id": "", "database": "GlyGen", "url": "https://data.glygen.org/" } ], "filter_code": "000000000000000010000.00000000001000.0.01000" } ], "phosphorylation": [], "glycation": [], "keywords": [ "glycoprotein", "glycoprotein_predicted" ], "publication": [], "pathway": [ { "id": "bta:540358", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?bta:540358", "resource": "KEGG Pathway" } ], "orthologs": [ { "uniprot_canonical_ac": "F1RQM0-1", "protein_name": "Trophoblast glycoprotein", "gene_name": "TPBG", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": 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"MPGGCSRGPAAGDGRLRLARLALVLLGWVSSSSPTSSASSFSSSAPFLASAVSAQPPLPDQCPALCECSEAARTVKCVNRNLTEVPTDLPAYVRNLFLTGNQLAVLPAGAFARRPPLAELAALNLSGSRLDEVRAGAFEHLPSLRQLDLSHNPLADLSPFAFSGSNASVSAPSPLVELILNHIVPPEDERQNRSFEGMVVAALLAGRALQGLRRLELASNHFLYLPRDVLAQLPSLRHLDLSNNSLVSLTYVSFRNLTHLESLHLEDNALKVLHNGTLAELQGLPHIRVFLDNNPWVCDCHMADMVTWLKETEVVQGKDRLTCAYPEKMRNRVLLELNSADLDCDPILPPSLQTSYVFLGIVLALIGAIFLLVLYLNRKGIKKWMHNIRDACRDHMEGYHYRYEINADPRLTNLSSNSDV", "length": 420 }, "evidence": [ { "id": "G3MYT4", "url": "https://omabrowser.org/oma/group/G3MYT4/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "Q5PQV5-1", "protein_name": "Trophoblast glycoprotein", "gene_name": "Tpbg", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MPGAGSRGPSAGDGRLRLARLALVLLGWVSASAPSSSLPSSSTSPAAFLASGSAQPPPAERCPAACECSEAARTVKCVNRNLLEVPADLPPYVRNLFLTGNQMTVLPAGAFARQPPLADLAVLNLSGNHLKEVGAGAFEHLPGLRRLDLSHNPLTNLSAFTFAGSNVSVSTPSPLLELILNHIVPPEDQRQNGSFEGMVAFEGMVAAALRSGLALRGLHHLELASNHFLYLPRDLLDQLPSLKHLDLRNNSLVSLTYASFRNLTHLESLHLEDNALKVLHNSTLAEWQGLAHVRVFLDNNPWVCDCYMADMVSWLKETEVVPDKARLTCAFPEKMRNRGLLDLTSSDLDCDATLPQSLQTSYVFLGIVLALIGAIFLLVLYLNRKGIKKWMHNIRDACRDHMEGYHYRYEINADPRLTNLSSNSDV", "length": 426 }, "evidence": [ { "id": "G3MYT4", "url": "https://omabrowser.org/oma/group/G3MYT4/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "Q9VGH2-1", "protein_name": "LRRCT domain-containing protein", "gene_name": "6959", "tax_id": 7227, "organism": "Drosophila melanogaster", "sequence": { "sequence": "MILVVAIAAIILAIGAGGVLGENSSSCGPNFPAACSCGQEMYESEMQYVVNCTNAGLVNTSVLEFMPEQVEVLIFTGNRITELPWNVFGSINNYKQLRIVDMSSNHIREIRGKSYHHVPRVERLILNHNNLSISRYEDEVNHHHPRVFSNFINLQSLHLTDAFEDNSSPQLSEDLHDIFVNSQLVKLQKLHLEQNEITHFKDRNVFCDLPSLRDLHLGDNDLRDLNFEVRCLNNLRFLDLERNKFSFVKPTDLRVLNELEERPNRTANLIVDFNLNPFGCDCRTAPFRAWITTTRVTVRNKDSLMCFHSTGHVDAEPAHLLQMDMGQCADAIAAAATILNTAEDEPHYGDPEASHLQPQAHISGHTATLIFLLIVLTMILLGLLVALVYVSRDKLKYMITPVFDNVAKKVQYTSIKDEDCPEVHV", "length": 425 }, "evidence": [ { "id": "G3MYT4", "url": "https://omabrowser.org/oma/group/G3MYT4/", "database": "OMA" } ], "glygen_name": "Fruit fly", "common_name": "Fruit fly" }, { "uniprot_canonical_ac": "Q9Z0L0-1", "protein_name": "Trophoblast glycoprotein", "gene_name": "Tpbg", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MPGAGSRGPSAGDGRLRLARLALVLLGWVSASAPSSSVPSSSTSPAAFLASGSAQPPPAERCPAACECSEAARTVKCVNRNLLEVPADLPPYVRNLFLTGNQMTVLPAGAFARQPPLADLEALNLSGNHLKEVCAGAFEHLPGLRRLDLSHNPLTNLSAFAFAGSNASVSAPSPLEELILNHIVPPEDQRQNGSFEGMVAFEGMVAAALRSGLALRGLTRLELASNHFLFLPRDLLAQLPSLRYLDLRNNSLVSLTYASFRNLTHLESLHLEDNALKVLHNSTLAEWHGLAHVKVFLDNNPWVCDCYMADMVAWLKETEVVPDKARLTCAFPEKMRNRGLLDLNSSDLDCDAVLPQSLQTSYVFLGIVLALIGAIFLLVLYLNRKGIKKWMHNIRDACRDHMEGYHYRYEINADPRLTNLSSNSDV", "length": 426 }, "evidence": [ { "id": "G3MYT4", "url": "https://omabrowser.org/oma/group/G3MYT4/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" } ], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 4, "go_terms": [ { "name": "endoplasmic reticulum", "id": "GO:0005783", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005783", "evidence": [ { "database": "UniProtKB", "id": "G3MYT4", "url": "https://www.uniprot.org/uniprotkb/G3MYT4" } ], "pmid": "" }, { "name": "plasma membrane", "id": "GO:0005886", "url": 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"categories": [ "Protein Classification" ] }, { "id": "PTHR28666", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR28666", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR28666:SF1", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR28666:SF1", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF15207", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF15207", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "NP_001193892", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001193892", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "G3MYY4", "url": "https://www.uniprot.org/uniprotkb/G3MYY4", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "G3MYY4-1", "url": "https://www.uniprot.org/uniprotkb/G3MYY4-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MSMSANTMIFMILGASIVMAIACLMDMNALLDRFHNYILPHLRGEDRVCHCNCGRHHVHYVIPYDGDQSVVDASENYFVTDNVTKQEIDLMLGLLLGFCISWFLVWMDGVLHCAVRAWRAGRRYDGSWTWLPKLCSLRELGRRPHRPFEEAAGNMVHVKQKLYHNGHPSPRHL", "length": 173, "header": "tr|G3MYY4-1|G3MYY4_BOVIN Isoform 1 of Transmembrane protein 240 OS=Bos taurus OX=9913 GN=TMEM240 PE=4 SV=2 CANONICAL=G3MYY4-1" }, "isoforms": [ { "isoform_ac": "G3MYY4-1", "url": "https://www.uniprot.org/uniprotkb/G3MYY4/entry", "sequence": { "sequence": "MSMSANTMIFMILGASIVMAIACLMDMNALLDRFHNYILPHLRGEDRVCHCNCGRHHVHYVIPYDGDQSVVDASENYFVTDNVTKQEIDLMLGLLLGFCISWFLVWMDGVLHCAVRAWRAGRRYDGSWTWLPKLCSLRELGRRPHRPFEEAAGNMVHVKQKLYHNGHPSPRHL", "length": 173, "header": "tr|G3MYY4-1|G3MYY4_BOVIN Isoform 1 of Transmembrane protein 240 OS=Bos taurus OX=9913 GN=TMEM240 PE=4 SV=2 CANONICAL=G3MYY4-1" }, "locus": { "chromosome": "16", "start_pos": 51084412, "end_pos": 51079299, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000065201.3", "url": "https://www.ensembl.org/id/ENSBTAT00000065201.3" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000054773.2", "url": "https://www.ensembl.org/id/ENSBTAP00000054773.2" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [ { "id": "bta:617545", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?bta:617545", "resource": "KEGG Pathway" } ], "orthologs": [ { "uniprot_canonical_ac": "A0A287A3F7-1", "protein_name": "Transmembrane protein 240", "gene_name": "TMEM240", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MSMSANTMIFMILGASIVMAIACLMDMNALLDRFHNYILPHLRGEDRVCHCDCGRHHVHYVIPYDGDQSVVDASENYFVTDNVTKQEIDLMLGLLLGFCISWFLVWMDGVLHCAVRAWRAGRRYDGSWTWLPKLCSLRELGRRPHRPFEEAAGNMVHVKQKLYHNGHPSPRHL", "length": 173 }, "evidence": [ { "id": "G3MYY4", "url": "https://omabrowser.org/oma/group/G3MYY4/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": 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"MGQNVELRPEGRGLSLRHRDRSGEPRPWMLARGGEVPPRRRRQEEEGGDSEEEKEGGRSLEEGRGRREGAAARTAGSRAQGAPEGGAEGCQQRATGERPHNSPHISAACARACPRGPRRPGARALTSAEAARAQHRAGAGRGTGAGGRRSGPARPRPMSMSANTMIFMILGASIVMAIACLMDMNALLDRFHNYILPHLRGEDRVCHCNCGRHHIHYVIPYDGDQSVVDASENYFVTDNVTKQEIDLMLGLLLGFCISWFLVWMDGVLHCAVRAWRAGRRYGECLALLRAPLLAQPGHLTALSPCRWLVDLAAQAVQPAGAGPAATQALRGAYREHGAREAEALPQRPPQPPAPVSAQDSGLLCTCKGTSWTPSWQDGTAASGPGYAGLWPAGLWPAGKSSGRCCLFFL", "length": 409 }, "evidence": [ { "id": "G3MYY4", "url": "https://omabrowser.org/oma/group/G3MYY4/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "B2RWJ3-1", "protein_name": "Transmembrane protein 240", "gene_name": "Tmem240", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MSMSANTMIFMILGASIVMAIACLMDMNALLDRFHNYILPHLRGEDRVCHCNCGRHHIHYVIPYDGDQSVVDASENYFVTDNVTKQEIDLMLGLLLGFCISWFLVWMDGVLHCAVRAWRAGRRYDGSWTWLPKLCSLRELGRRPHRPFEEPTGNMVHVKQKLYHNGHPSPRHL", "length": 173 }, "evidence": [ { "id": "G3MYY4", "url": 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"MSMSANTMIFMILGASVVMAIACLMDMNALLDRFHNYILPHLRGEDRVCHCNCGRHHIHYVIPYDGDQSVVDASENYFVTDSVTKQEIDLMLGLLLGFCISWFLVWMDGVLHCAVRAWRAGRRYDGSWTWLPKLCSLRELGRRPHRPFEEAAGNMVHVKQKLYHNGHPSPRHL", "length": 173 }, "evidence": [ { "id": "G3MYY4", "url": "https://omabrowser.org/oma/group/G3MYY4/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" } ], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 5, "go_terms": [ { "name": "synaptic membrane", "id": "GO:0097060", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0097060", "evidence": [ { "database": "UniProtKB", "id": "G3MYY4", "url": "https://www.uniprot.org/uniprotkb/G3MYY4" } ], "pmid": "" }, { "name": "postsynaptic density membrane", "id": "GO:0098839", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0098839", "evidence": [ { "database": "UniProtKB", "id": "G3MYY4", "url": "https://www.uniprot.org/uniprotkb/G3MYY4" } ], "pmid": "" }, { "name": "parallel fiber to Purkinje cell synapse", "id": "GO:0098688", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0098688", "evidence": [ { "database": "UniProtKB", "id": "G3MYY4", "url": "https://www.uniprot.org/uniprotkb/G3MYY4" } ], "pmid": "" }, { "name": "cerebellar climbing fiber to Purkinje cell synapse", "id": "GO:0150053", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0150053", "evidence": [ { "database": "UniProtKB", "id": "G3MYY4", "url": "https://www.uniprot.org/uniprotkb/G3MYY4" } ], "pmid": "" }, { "name": "TMEM240-body", "id": "GO:0160045", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0160045", "evidence": [ { "database": "UniProtKB", "id": "G3MYY4", "url": "https://www.uniprot.org/uniprotkb/G3MYY4" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 82, "end_pos": 84, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [ { "pdb_id": "AF-G3MYY4-F1", "pdb_chain": 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{ "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": 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"database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR050944", "url": "https://www.ebi.ac.uk/interpro/entry/IPR050944", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "bta:100851343", "url": "https://www.genome.jp/dbget-bin/www_bget?bta:100851343", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "TYWPGRS", "url": "https://omabrowser.org/oma/group/TYWPGRS/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "G3MYY9", "url": "https://www.orthodb.org/?gene=G3MYY9", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR16181", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR16181", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR16181:SF29", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR16181:SF29", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF07894", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF07894", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "XP_059733575", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_059733575", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "G3MYY9", "url": "https://www.uniprot.org/uniprotkb/G3MYY9", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "G3MYY9-1", "url": "https://www.uniprot.org/uniprotkb/G3MYY9-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MAASQLAALEGMDPGPGGRPQTEASPGFLYSEGQRLALETLLGEGVEAFEACLRREGLRPFLGGEELRGLVAAAEDWTAAKPEPGGAAEGADAAHGVSGSLTYWPGQSEEAVPVLRLGWPEDSAWKGITRAQLYTQPPGEGQPSLKELVHQEIRAAHKLVAVVMDVFTDPDLLSDLVEAATCRWVPVYLLLDRQQLPAFLTLAQQLGVNPWATENLDIRVVRGCSFQSRWRRQVSGNVREKFVLLDGERVISGSYSFTWSDSRLHRGLVTLLTGEITDAFSREFRTLYAASGPLPPAPTPGPFVRTLGGLQLAHSPHRVAHRCSVAPLSPPPPPDGSLTQRLAACRVFEGDRQETLAAPGPALSDILRSVQRARIPSGPPTRPSRSLWDLSRLSQLSGSSDGDNDELKKSWGSKDTPAKALMRQRGAGGAPGGEADTRPLAWSQPWGGPLPLTPGHRLRYLSPTRRRFGKDAASKLLEPRGIRQPDGATQPGLRGQLWP", "length": 499, "header": "tr|G3MYY9-1|G3MYY9_BOVIN Isoform 1 of Family with sequence similarity 83 member E OS=Bos taurus OX=9913 GN=FAM83E PE=3 SV=2 CANONICAL=G3MYY9-1" }, "isoforms": [ { "isoform_ac": "G3MYY9-1", "url": "https://www.uniprot.org/uniprotkb/G3MYY9/entry", "sequence": { "sequence": "MAASQLAALEGMDPGPGGRPQTEASPGFLYSEGQRLALETLLGEGVEAFEACLRREGLRPFLGGEELRGLVAAAEDWTAAKPEPGGAAEGADAAHGVSGSLTYWPGQSEEAVPVLRLGWPEDSAWKGITRAQLYTQPPGEGQPSLKELVHQEIRAAHKLVAVVMDVFTDPDLLSDLVEAATCRWVPVYLLLDRQQLPAFLTLAQQLGVNPWATENLDIRVVRGCSFQSRWRRQVSGNVREKFVLLDGERVISGSYSFTWSDSRLHRGLVTLLTGEITDAFSREFRTLYAASGPLPPAPTPGPFVRTLGGLQLAHSPHRVAHRCSVAPLSPPPPPDGSLTQRLAACRVFEGDRQETLAAPGPALSDILRSVQRARIPSGPPTRPSRSLWDLSRLSQLSGSSDGDNDELKKSWGSKDTPAKALMRQRGAGGAPGGEADTRPLAWSQPWGGPLPLTPGHRLRYLSPTRRRFGKDAASKLLEPRGIRQPDGATQPGLRGQLWP", "length": 499, "header": "tr|G3MYY9-1|G3MYY9_BOVIN Isoform 1 of Family with sequence similarity 83 member E OS=Bos taurus OX=9913 GN=FAM83E PE=3 SV=2 CANONICAL=G3MYY9-1" }, "locus": { "chromosome": "18", "start_pos": 55257555, "end_pos": 55248323, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000063630.3", "url": "https://www.ensembl.org/id/ENSBTAT00000063630.3" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000054778.2", "url": "https://www.ensembl.org/id/ENSBTAP00000054778.2" } ] } } ], "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "other", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 299, "start_aa": "Thr", "end_pos": 299, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr299", "evidence": [ { "id": "", "database": "GlyGen", "url": "https://data.glygen.org/" } ], "filter_code": "000000000000000010000.00000000001000.0.01000" } ], "phosphorylation": [], "glycation": [], "keywords": [ "glycoprotein", "glycoprotein_predicted" ], "publication": [], "pathway": [ { "id": "bta:100851343", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?bta:100851343", "resource": "KEGG Pathway" } ], "orthologs": [ { "uniprot_canonical_ac": "D3ZT45-1", "protein_name": "Family with sequence similarity 83, member E", "gene_name": "Fam83e", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MAASQLAALEGEELGAVEPAPTKACPASLYSEGQRLALEALLSSGEEAFWACVQQERLPPFLSADEAQALATAAEDWIVPSQEPGATGTGAGIADGDFGSLTYWPRQSEEPAPSLRLGWPEDIAWKGITRAQLYTQPPGEGQPPVKELVRQEIQAARKLVAVVMDIFTDPDLLRDMVDAATRRWIPVYLLLDHQHLPAFLALAQQLGVNLWTTENLDIRTVQGHTFQSRRRRQVSGHVREKFLLLDGDRVISGSYSFTWSDSRLHRGLVTLLTGEIADAFSQEFRVLYAASRPLPPAPARSPLFSPPEGPQLPRSPHRVALRCPVAPVAPLLSDGPLAHRLAACHILEGDRRETPTTTGPALSDILRSVQRTRTTSGPPTRPSRSLWDLSRLSQLSGSSDGENEPKKSWGSKDTPARALMRQRGTGGGPRAEMDLRSQPWVGPLPIPAQRRLRYLSPAQRRLGDNATTSDWASGSGSGRRR", "length": 481 }, "evidence": [ { "id": "G3MYY9", "url": "https://omabrowser.org/oma/group/G3MYY9/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "Q2M2I3-1", "protein_name": "Protein FAM83E", "gene_name": "FAM83E", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MAASQLAALEGVDSGPRVPGASPGFLYSEGQRLALEALLSKGAEAFQTCVQREELWPFLSADEVQGLAAAAEDWTVAKQEPSGMAEGATTTDVDAGSLSYWPGQSEQPAPVLRLGWPVDSAWKGITRAQLYTQPPGEGQPPLKELVRLEIQAAHKLVAVVMDVFTDPDLLLDLVDAATRRWVPVYLLLDRQQLPAFLELAQQLGVNPWNTENVDVRVVRGCSFQSRWRRQVSGTVREKFVLLDGERVISGSYSFTWSDARLHRGLVTLLTGEIVDAFSLEFRTLYAASCPLPPAPPQKPSVIGGLQRGRSPHRVSRRRSVAPASPPPPDGPLAHRLAACRVSPATPGPALSDILRSVQRARTPSGPPARPSRSMWDLSRLSQLSGSSDGDNELKKSWGSKDTPAKALMRQRGTGGGPWGEVDSRPPWGGALPLPPAHRLRYLSPARRRFGGDATFKLQEPRGVRPSDWAPRAGLGGQP", "length": 478 }, "evidence": [ { "id": "G3MYY9", "url": "https://omabrowser.org/oma/group/G3MYY9/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "Q80XS7-1", "protein_name": "Protein FAM83E", "gene_name": "Fam83e", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MAASQLAALEGEELGAGEPALTKASPAVLYSEGQRLALEALLSSGEETFWACVQQERLPPFLSADEAQALATAAEDWLVPSQEPGAAGTGTAITDGDVGSLTYWPRQSEEPAPLLRLGWPEDTAWKGITRAQLYTQPPGEGQPPIKELVHQEIQAARKLVAVVMDVFTDPDLLRDMVDAATRRWIPVYLLLDHQHLPAFLALAQQLGVNLWTTENLDIRTVQGHTFQSRRRRQVSGHVREKFVLLDGDRVISGSYSFTWSDSRLHRSLVTLLTGEIADAFNQEFRVLYAASRPLSAAPARSPLFSPPEGPQLPRSPHRVALRCPVAPVAPLLSDGPLAQRLAACHILERDKQETPTTTGPALSDILRSVQRTRTTSGPPTRPSRSLWDLSRLSQLSGSSDGENESKKFWVSKDTPARALMRQRGTGGGPRAEMDSRSQPWGGPLPSIPARRLRYLSPAQRRLGDNATTSDWASGSGSGRRR", "length": 481 }, "evidence": [ { "id": "G3MYY9", "url": "https://omabrowser.org/oma/group/G3MYY9/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" } ], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 1, "go_terms": [ { "name": "cytoplasm", "id": "GO:0005737", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005737", "evidence": [ { "database": "UniProtKB", "id": "G3MYY9", "url": "https://www.uniprot.org/uniprotkb/G3MYY9" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 1, "go_terms": [ { "name": "signal transduction", "id": "GO:0007165", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007165", "evidence": [ { "database": "UniProtKB", "id": "G3MYY9", "url": "https://www.uniprot.org/uniprotkb/G3MYY9" } ], "pmid": "" } ] }, { "name": "Molecular Function", "total": 1, "go_terms": [ { "name": "protein kinase binding", "id": "GO:0019901", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0019901", "evidence": [ { "database": "UniProtKB", "id": "G3MYY9", "url": "https://www.uniprot.org/uniprotkb/G3MYY9" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [ { "pdb_id": "AF-G3MYY9-F1", "pdb_chain": "global", "start_pos": 1, "end_pos": 499, "overlap": "1.0", "method": "AlphaFold", "type": "alphafold", "resolution": -1.0, "url": "https://data.glygen.org/ln2downloads/pdb/current/AF-G3MYY9-F1.pdb", "url_external": "https://alphafold.ebi.ac.uk/entry/G3MYY9" } ], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "G3MYY9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3MYY9" }, { "id": "PF07894", "database": "Pfam", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF07894" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "Scaffolding anchor of CK1", "eco_id": "ECO_0000259", "start_pos": 20, "end_pos": 292, "start_aa": "Pro", "end_aa": "Gly", "glycosite_overlap": [] } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "homologset.oma", "label": "OMA Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [ 299 ], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 1 }, { "field": "total_sites", "count": 1 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 1 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "exact_sites", "count": 1 }, { "field": "exact_o_linked_sites", "count": 1 }, { "field": "fuzzy_sites", "count": 0 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_pos", "start_aa", "end_pos", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 1 }, { "field": "total_sites", "count": 1 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 1 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "exact_sites", "count": 1 }, { "field": "exact_o_linked_sites", "count": 1 }, { "field": "fuzzy_sites", "count": 0 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_pos", "start_aa", "end_pos", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ], "tool_support": { "graph_view": "yes" } }, { "uniprot_canonical_ac": "G3MZ09-1", "uniprot_ac": "G3MZ09", "uniprot_id": "G3MZ09_BOVIN", "mass": { "chemical_mass": 36508.0, "monoisotopic_mass": 36508.0 }, "refseq": {}, "gene_names": [ { "name": "SPACA6", "type": "recommended", "evidence": [ { "id": "G3MZ09", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3MZ09" } ] } ], "protein_names": [ { "name": "Sperm acrosome associated 6", "type": "synonym", "evidence": [ { "id": "G3MZ09", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3MZ09/entry#names_and_taxonomy" } ] } ], "function": [], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Bos taurus", "taxid": 9913, "evidence": [ { "database": "UniProtKB", "id": "G3MZ09", "url": "https://www.uniprot.org/uniprotkb/G3MZ09" } ], "common_name": "Bovine", "glygen_name": "Bovine", "reference_species": "Bos taurus [9913]" } ], "gene": [ { "name": "SPACA6", "url": "https://www.uniprot.org/uniprotkb/G3MZ09", "locus": { "chromosome": "18", "start_pos": 57699513, "end_pos": 57689634, "strand": "-", "evidence": [ { "database": "Ensembl Gene", "id": "ENSBTAG00000048204", "url": "https://www.ensembl.org/id/ENSBTAG00000048204" } ] } } ], "crossref": [ { "id": "G3MZ09", "url": "https://alphafold.ebi.ac.uk/entry/G3MZ09", "database": "AlphaFoldDB", "categories": [] }, { "id": "ENSBTAG00000048204", "url": "https://bgee.org/?page=gene&gene_id=ENSBTAG00000048204", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "cd00096", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd00096", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "IPR007110", "url": "https://www.ebi.ac.uk/interpro/entry/IPR007110", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR013783", "url": "https://www.ebi.ac.uk/interpro/entry/IPR013783", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR034549", "url": "https://www.ebi.ac.uk/interpro/entry/IPR034549", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR036179", "url": "https://www.ebi.ac.uk/interpro/entry/IPR036179", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "PTHR37366", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR37366", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR37366:SF1", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR37366:SF1", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "A0ABI0NY03", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NY03", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0ABI0NY03-1", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NY03-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "G3MZ09", "url": "https://www.uniprot.org/uniprotkb/G3MZ09", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "G3MZ09-1", "url": "https://www.uniprot.org/uniprotkb/G3MZ09-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MAWLAPWSAVLPSLAAFAVFGASAWACLLCFTSYEERLQICQIFAGLDSPDLGKCEEAFADAFKGLLDTEINYEERGQLHDAFTQMTHSLQEMATAQGSFRVAFLRAAEKMQKIILQLKEVQVCIPPCGLQEVTRRFRCRGCYSKVCDLPLDCPVQDLTVTRGRQAMFSCTVNFQLPKEEITYSWKFAGGLRTQDPTYFRDIPRAQGYLARIRPVQPTHRGTFSCVITHDQRPLARLYFFLNVTGPPPRGETELQVSFREVLRWVPQEAEMIEPWRPSLGELLARPEALTPGNQCLLAALVALASASVTVLVWMFFRWYCSGN", "length": 323, "header": "tr|G3MZ09-1|G3MZ09_BOVIN Isoform 1 of Sperm acrosome associated 6 OS=Bos taurus OX=9913 GN=SPACA6 PE=4 SV=3 CANONICAL=G3MZ09-1" }, "isoforms": [ { "isoform_ac": "A0ABI0NY03-1", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NY03/entry", "sequence": { "sequence": "MRSVSRFARSSPAWTVPTSESVRRPSQMPLRGCWTLRSVRRPSPAPHHPPWVGCPGVGGGRDPRGLERLRGTRCRDGRMETWGAEIGDRGMTTSGTWCQGKQFSPSPCLPLPDYEERGQLHDAFTQMTHSLQEMATAQGSFRVAFLRAAEKMQKIILQLKEVQVCIPPCGLQEVTRRFRCRGCYSKVCDLPLDCPVQDLTVTRGRQAMFSCTVNFQLPKEEITYSWKFAGGLRTQDPTYFRDIPRAQGYLARIRPVQPTHRGTFSCVITHDQRPLARLYFFLNVTGPPPRGETELQVSFREVLRWVPQEAEMIEPWRPSLGELLARPEALTPGNQCLLAALVALASASVTVLVWMFFRWYCSGN", "length": 364, "header": "tr|A0ABI0NY03-1|A0ABI0NY03_BOVIN Computationally mapped isoform of Sperm acrosome associated 6 OS=Bos taurus OX=9913 GN=SPACA6 PE=4 SV=1 CANONICAL=G3MZ09-1" }, "locus": { "chromosome": "18", "start_pos": 57699510, "end_pos": 57689933, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000144488.1", "url": "https://www.ensembl.org/id/ENSBTAT00000144488.1" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000106931.1", "url": "https://www.ensembl.org/id/ENSBTAP00000106931.1" } ] } }, { "isoform_ac": "G3MZ09-1", "url": "https://www.uniprot.org/uniprotkb/G3MZ09/entry", "sequence": { "sequence": "MAWLAPWSAVLPSLAAFAVFGASAWACLLCFTSYEERLQICQIFAGLDSPDLGKCEEAFADAFKGLLDTEINYEERGQLHDAFTQMTHSLQEMATAQGSFRVAFLRAAEKMQKIILQLKEVQVCIPPCGLQEVTRRFRCRGCYSKVCDLPLDCPVQDLTVTRGRQAMFSCTVNFQLPKEEITYSWKFAGGLRTQDPTYFRDIPRAQGYLARIRPVQPTHRGTFSCVITHDQRPLARLYFFLNVTGPPPRGETELQVSFREVLRWVPQEAEMIEPWRPSLGELLARPEALTPGNQCLLAALVALASASVTVLVWMFFRWYCSGN", "length": 323, "header": "tr|G3MZ09-1|G3MZ09_BOVIN Isoform 1 of Sperm acrosome associated 6 OS=Bos taurus OX=9913 GN=SPACA6 PE=4 SV=3 CANONICAL=G3MZ09-1" }, "locus": { "chromosome": "18", "start_pos": 57699510, "end_pos": 57689833, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000065736.3", "url": "https://www.ensembl.org/id/ENSBTAT00000065736.3" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000054799.3", "url": "https://www.ensembl.org/id/ENSBTAP00000054799.3" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [], "orthologs": [], "go_annotation": { "categories": [ { "name": "Biological Process", "total": 1, "go_terms": [ { "name": "fusion of sperm to egg plasma membrane involved in single fertilization", "id": "GO:0007342", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007342", "evidence": [ { "database": "UniProtKB", "id": "G3MZ09", "url": "https://www.uniprot.org/uniprotkb/G3MZ09" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 242, "end_pos": 244, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [ { "pdb_id": "AF-G3MZ09-F1", "pdb_chain": "global", "start_pos": 1, "end_pos": 323, "overlap": "1.0", "method": "AlphaFold", "type": "alphafold", "resolution": -1.0, "url": "https://data.glygen.org/ln2downloads/pdb/current/AF-G3MZ09-F1.pdb", "url_external": "https://alphafold.ebi.ac.uk/entry/G3MZ09" } ], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "G3MZ09", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3MZ09" }, { "id": "PS50835", "database": "PROSITE", "url": "https://prosite.expasy.org/PS50835" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "Ig-like", "eco_id": "ECO_0000259", "start_pos": 150, "end_pos": 235, "start_aa": "Pro", "end_aa": "Ala", 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"https://data.glygen.org/ln2downloads/pdb/current/AF-G3MZ21-F1.pdb", "url_external": "https://alphafold.ebi.ac.uk/entry/G3MZ21" } ], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "G3MZ21", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3MZ21" }, { "id": "PS01033", "database": "PROSITE", "url": "https://prosite.expasy.org/PS01033" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "Globin", "eco_id": "ECO_0000259", "start_pos": 3, "end_pos": 147, "start_aa": "His", "end_aa": "His", "glycosite_overlap": [] } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 48, "end_pos": 50 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": 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"G3MZ24-1", "uniprot_ac": "G3MZ24", "uniprot_id": "G3MZ24_BOVIN", "mass": { "chemical_mass": 189881.0, "monoisotopic_mass": 189881.0 }, "refseq": { "ac": "XP_010802796", "name": "kielin/chordin-like protein isoform X1", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_010802796" }, "gene_names": [ { "name": "KCP", "type": "recommended", "evidence": [ { "id": "G3MZ24", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3MZ24" } ] }, { "name": "KCP", "type": "synonym", "evidence": [ { "id": "XP_010802796", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_010802796" } ] } ], "protein_names": [ { "name": "Kielin cysteine rich BMP regulator", "type": "synonym", "evidence": [ { "id": "G3MZ24", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3MZ24/entry#names_and_taxonomy" } ] }, { "name": "kielin/chordin-like protein isoform X1", "type": "synonym", "evidence": [ { "id": "XP_010802796", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_010802796" } ] } ], "function": [], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Bos taurus", "taxid": 9913, "evidence": [ { "database": "UniProtKB", "id": "G3MZ24", "url": "https://www.uniprot.org/uniprotkb/G3MZ24" } ], "common_name": "Bovine", "glygen_name": "Bovine", "reference_species": "Bos taurus [9913]" } ], "gene": [ { "name": "KCP", "url": "https://www.uniprot.org/uniprotkb/G3MZ24", "locus": { "chromosome": "4", "start_pos": 92843779, "end_pos": 92874824, "strand": "+", "evidence": [ { "database": "Ensembl Gene", "id": "ENSBTAG00000003449", "url": "https://www.ensembl.org/id/ENSBTAG00000003449" } ] } } ], "crossref": [ { "id": "ENSBTAG00000003449", "url": "https://bgee.org/?page=gene&gene_id=ENSBTAG00000003449", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "cd19941", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd19941", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "515624", "url": "https://www.ncbi.nlm.nih.gov/gene/515624", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR001007", "url": "https://www.ebi.ac.uk/interpro/entry/IPR001007", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR001846", "url": "https://www.ebi.ac.uk/interpro/entry/IPR001846", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR014853", "url": "https://www.ebi.ac.uk/interpro/entry/IPR014853", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR036084", "url": "https://www.ebi.ac.uk/interpro/entry/IPR036084", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR052424", "url": "https://www.ebi.ac.uk/interpro/entry/IPR052424", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "bta:515624", "url": "https://www.genome.jp/dbget-bin/www_bget?bta:515624", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "E1B9L4", "url": "https://www.orthodb.org/?gene=E1B9L4", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "G3MZ24", "url": "https://www.orthodb.org/?gene=G3MZ24", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR46698", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR46698", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR46698:SF2", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR46698:SF2", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00093", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00093", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF00094", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00094", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF23334", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF23334", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "XP_010802796", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_010802796", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "E1B9L4", "url": "https://www.uniprot.org/uniprotkb/E1B9L4", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "E1B9L4-1", "url": "https://www.uniprot.org/uniprotkb/E1B9L4-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "G3MZ24", "url": "https://www.uniprot.org/uniprotkb/G3MZ24", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "G3MZ24-1", "url": "https://www.uniprot.org/uniprotkb/G3MZ24-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MQEKSPPLASSFRPPRHSPAPLSRGWGQDGGAIRQAGTTGLDDRHQKPSLNKGWVGGGLVCPHPPSLCLLSQDCSQQGGESMARAVAVLLSLILQLASRTLAPGTSRGGAISREPLGLADIQDYQSEGPAHSSAPAGVPEEWWRPLEEQLERLEAEVTELREQNKDLQGRVTQLESCECHPASPQCWGLGRAWPEGARWEPDACTACVCQDGAANCVPKPGLARCHGCSHNGQAYGNGETFTPDACTICRCLEGAVTCTQKPCPRGPCQEPGACCPHCCPGGYRDGEMWQLERCVICTCQAGTVRCQGPSCSELNCLESYTPPGECCPVCRPGCEYEGQLYEEGANFWSSSNPCLQCSCLRSLVRCVPTKCPPIPCPKPVLRPGHCCPTCQAQGCTENGSHWEHGQEWTTPGDPCRICQCLEGHILCRQRECASLCPYPARPLPGTCCPVCDGCFLNGRDYRSGEPVGSGDPCSRCRCVNGSVQCEPPPCPPTPCRHPGRTPGECCPVCDSCEYQGHKYQNQETFQLQESGRCAHCSCQAGEVSCEERECPGMPCTLPDSGPEPCSVCVLDGEEFAEGVQWEPDGQPCTTCSCQAGVPVCGTLLCSPAPCQHPTQPPGACCPSCENCTYHGQVYANGQNFTDADPCHTCHCEDGTVTCSLVNCPPTTCARPQRGPSQCCPRCPDCVLEKQVFLDGERFSHPRDPCQECQCREGHAHCQPRLCPRTSCAHPLPGVCCQNNCNGCAFGGKEYPNGADFPHPSDPCRLCHCLGGTVQCLARRCPPLPCPEPVLLPRQCCPRCPAAPSGCPRPGGLVPAHHQEYFSPPDDPCRRCLCLDGSVSCRRLPCPPVPCTHPHQGPCCPSCDGCLYQGKEFTSGERFPSPTARCHICLCWEGSISCEPRACAPAQCPFPAQGDCCPACDGCEYLGESYLSGQEFPDPREPCNLCTCLGGFVTCGRRPCEPLGCSHPLTRAGHCCPTCQGCLYHGVTAAPGETLPDPLDPACSLCTCQEGSMRCQKKPCPPALCPRPSSGPCFCPVCHSCLSQGQEHQDGEEFEGPTGSCERCLCQAGQVSCVRQRCPPLSCPLQVTEPGSCCPRCRGCLFHGEEHPEGSSWKPPDSPCSSCMCHEGVITCARIQCVTSCAQPHQGPSDCCPRCSDCEHEGRKYEPGESFQPGADPCEVCVCELQPEGTPSLRCHRRQCPHLAGCPTSQLLTPGPQQCCPTCAEALSHCTEHLLGSELTPPDPCYSCQCQDLTWLCIHRACPELSCPLPERYIPSGSCCPMCQDCVVEAAGRTAADGESWRDPSNACVTCTCRRGHVECRLEECQALTCPRGWAKVREAGRCCERCQAPAPSCAHQGRQVASGERWDVDACTNCSCMAGTVRCQSQRCPPLSCGPDEAPALSPGSCCPRCLPRPASCMAFGDPHYRTFDGRLLHFQGSCSYVLAKDCRGGDFSVHVTNDDRGRSGVSWTQEVAVLLGDVAVRLLQDRAVTVDGRPVALPFLQEPLFYVELRGRTVVLHSQPGLQVLWDGRSQVEVRVPGSYRGHMCGLCGNFNGFAQDDLRDPEELLRSTEAAFGNSWQVPEGPGPGRPCSKGREVDPCQAAGYRARREANARCAVLKSAPFSRCHAVVPPDPFFAACVYDLCACGPGSSSDACLCDALEAYASHCRQAGVTPAWRGPTLCVVGCPLDRGFVFDECGPPCPRTCFNKHVPLGELAAHCVRPCIPGCQCPAGLVEHEGHCISPEACPSVLLTGDQLPSTPRNPSQELQGPT", "length": 1770, "header": "tr|G3MZ24-1|G3MZ24_BOVIN Isoform 1 of Kielin cysteine rich BMP regulator OS=Bos taurus OX=9913 GN=KCP PE=4 SV=3 CANONICAL=G3MZ24-1" }, "isoforms": [ { "isoform_ac": "E1B9L4-1", "url": "https://www.uniprot.org/uniprotkb/E1B9L4/entry", "sequence": { "sequence": "MVAPPGGAAGKAGGRGHGAQRTGCSHNGQAYGNGETFTPDACTICRCLEGAVTCTQKPCPRGPCQEPGACCPHCCPGGYRDGEMWQLERCVICTCQAGTVRCQGPSCSELNCLESYTPPGECCPVCRPGCEYEGQLYEEGANFWSSSNPCLQCSCLRSLVRCVPTKCPPIPCPKPVLRPGHCCPTCQAQGCTENGSHWEHGQEWTTPGDPCRICQCLEGHILCRQRECASLCPYPARPLPGTCCPVCDGCFLNGRDYRSGEPVGSGDPCSRCRCVNGSVQCEPPPCPPTPCRHPGRTPGECCPVCDSCEYQGHKYQNQETFQLQESGRCAHCSCQAGEVSCEERECPGMPCTLPDSGPEPCSVCVLDGEEFAEGVQWEPDGQPCTTCSCQAGVPVCGTLLCSPAPCQHPTQPPGACCPSCENCTYHGQVYANGQNFTDADPCHTCHCEDGTVTCSLVNCPPTTCARPQRGPSQCCPRCPDCVLEKQVFLDGERFSHPRDPCQECQCREGHAHCQPRLCPRTSCAHPLPGVCCQNNCNGCAFGGKEYPNGADFPHPSDPCRLCHCLGGTVQCLARRCPPLPCPEPVLLPRQCCPRCPAAPSGCPRPGGLVPAHHQEYFSPPDDPCRRCLCLDGSVSCRRLPCPPVPCTHPHQGPCCPSCDGCLYQGKEFTSGERFPSPTARCHICLCWEGSISCEPRACAPAQCPFPAQGDCCPACDGCEYLGESYLSGQEFPDPREPCNLCTCLGGFVTCGRRPCEPLGCSHPLTRAGHCCPTCQGCLYHGVTAAPGETLPDPLDPACSLCTCQEGSMRCQKKPCPPALCPRPSSGPCFCPVCHSCLSQGQEHQDGEEFEGPTGSCERCLCQAGQVSCVRQRCPPLSCPLQVTEPGSCCPRCRGCLFHGEEHPEGSSWKPPDSPCSSCMCHEGVITCARIQCVTSCAQPHQGPSDCCPRCSDCEHEGRKYEPGESFQPGADPCEVCVCELQPEGTPSLRCHRRQCPHLAGCPTSQLLTPGPQQCCPTCAEALSHCTEHLLGSELTPPDPCYSCQCQDLTWLCIHRACPELSCPLPERYIPSGSCCPMCQDCVVEAAGRTAADGESWRDPSNACVTCTCRRGHVECRLEECQALTCPRGWAKVREAGRCCERCQAPAPSCAHQGRQVASGERWDVDACTNCSCMAGTVRCQSQRCPPLSCGPDEAPALSPGSCCPRCLPRPASCMAFGDPHYRTFDGRLLHFQGSCSYVLAKDCRGGDFSVHVTNDDRGRSGVSWTQEVAVLLGDVAVRLLQDRAVTVDGRPVALPFLQEPLFYVELRGRTVVLHSQPGLQVLWDGRSQVEVRVPGSYRGHMCGLCGNFNGFAQDDLRDPEELLRSTEAAFGNSWQVPEGPGPGRPCSKGREVDPCQAAGYRARREANARCAVLKSAPFSRCHAVVPPDPFFAACVYDLCACGPGSSSDACLCDALEAYASHCRQAGVTPAWRGPTLCVVGCPLDRGFVFDECGPPCPRTCFNKHVPLGELAAHCVRPCIPGCQCPAGLVEHEGHCISPEACPSVLLTGDQLPSTPRNPSQELQGPT", "length": 1566, "header": "tr|E1B9L4-1|E1B9L4_BOVIN Computationally mapped isoform of Kielin cysteine rich BMP regulator OS=Bos taurus OX=9913 GN=KCP PE=4 SV=4 CANONICAL=G3MZ24-1" }, "locus": { "chromosome": "4", "start_pos": 92869909, "end_pos": 92843939, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000033567.6", "url": "https://www.ensembl.org/id/ENSBTAT00000033567.6" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000033479.6", "url": "https://www.ensembl.org/id/ENSBTAP00000033479.6" } ] } }, { "isoform_ac": "G3MZ24-1", "url": "https://www.uniprot.org/uniprotkb/G3MZ24/entry", "sequence": { "sequence": 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"PF00074", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00074", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "XP_024853726", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_024853726", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "G3MZ45", "url": "https://www.uniprot.org/uniprotkb/G3MZ45", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "G3MZ45-1", "url": "https://www.uniprot.org/uniprotkb/G3MZ45-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MEIFFLLLLGLGVIFAGVSESIMEIIKEEFLEKEMKYDMAKSYQEKHTIEVLINLTVSYKNTSLSMSKDVSSSLLTFRRLHYSLPPKCNPGNNKHYCNDMTVWRKVSEANGSFKLSNNFIHGSVEVVDGVPKAPSCKCGQTSGISCSETPELRTTTCQFTVGKQSPSCQHHGVTSLKKILVVLTSHSLMSWLVSVSNL", "length": 198, "header": "tr|G3MZ45-1|G3MZ45_BOVIN Isoform 1 of Ribonuclease A family member 11 (inactive) OS=Bos taurus OX=9913 GN=RNASE11 PE=3 SV=1 CANONICAL=G3MZ45-1" }, "isoforms": [ { "isoform_ac": "G3MZ45-1", "url": "https://www.uniprot.org/uniprotkb/G3MZ45/entry", "sequence": { "sequence": "MEIFFLLLLGLGVIFAGVSESIMEIIKEEFLEKEMKYDMAKSYQEKHTIEVLINLTVSYKNTSLSMSKDVSSSLLTFRRLHYSLPPKCNPGNNKHYCNDMTVWRKVSEANGSFKLSNNFIHGSVEVVDGVPKAPSCKCGQTSGISCSETPELRTTTCQFTVGKQSPSCQHHGVTSLKKILVVLTSHSLMSWLVSVSNL", "length": 198, "header": "tr|G3MZ45-1|G3MZ45_BOVIN Isoform 1 of Ribonuclease A family member 11 (inactive) OS=Bos taurus OX=9913 GN=RNASE11 PE=3 SV=1 CANONICAL=G3MZ45-1" }, "locus": { "chromosome": "10", "start_pos": 26511939, "end_pos": 26511346, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000063357.2", "url": "https://www.ensembl.org/id/ENSBTAT00000063357.2" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000054837.1", "url": "https://www.ensembl.org/id/ENSBTAP00000054837.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [], "orthologs": [ { "uniprot_canonical_ac": "F7F9F0-1", "protein_name": 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"pmid": "" } ] }, { "name": "Biological Process", "total": 1, "go_terms": [ { "name": "defense response to Gram-positive bacterium", "id": "GO:0050830", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0050830", "evidence": [ { "database": "UniProtKB", "id": "G3MZ45", "url": "https://www.uniprot.org/uniprotkb/G3MZ45" } ], "pmid": "" } ] }, { "name": "Molecular Function", "total": 1, "go_terms": [ { "name": "nucleic acid binding", "id": "GO:0003676", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003676", "evidence": [ { "database": "UniProtKB", "id": "G3MZ45", "url": "https://www.uniprot.org/uniprotkb/G3MZ45" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 110, "end_pos": 112, "annotation": "n_glycosylation_sequon" }, { "start_pos": 54, "end_pos": 56, "annotation": "n_glycosylation_sequon" }, { "start_pos": 61, "end_pos": 63, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": 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"https://www.ncbi.nlm.nih.gov/protein/NP_001178066" } ] } ], "protein_names": [ { "name": "CGG triplet repeat binding protein 1", "type": "synonym", "evidence": [ { "id": "G3MZ52", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3MZ52/entry#names_and_taxonomy" } ] }, { "name": "CGG triplet repeat-binding protein 1", "type": "synonym", "evidence": [ { "id": "NP_001178066", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001178066" } ] } ], "function": [], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Bos taurus", "taxid": 9913, "evidence": [ { "database": "UniProtKB", "id": "G3MZ52", "url": "https://www.uniprot.org/uniprotkb/G3MZ52" } ], "common_name": "Bovine", "glygen_name": "Bovine", "reference_species": "Bos taurus [9913]" } ], "gene": [ { "name": "CGGBP1", "url": "https://www.uniprot.org/uniprotkb/G3MZ52", "locus": { "chromosome": "1", "start_pos": 36056517, "end_pos": 36064659, "strand": "+", "evidence": [ { "database": "Ensembl Gene", "id": "ENSBTAG00000046959", "url": "https://www.ensembl.org/id/ENSBTAG00000046959" } ] } } ], "crossref": [ { "id": "ENSBTAG00000046959", "url": "https://bgee.org/?page=gene&gene_id=ENSBTAG00000046959", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "613824", "url": "https://www.ncbi.nlm.nih.gov/gene/613824", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR033375", "url": "https://www.ebi.ac.uk/interpro/entry/IPR033375", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "bta:613824", "url": "https://www.genome.jp/dbget-bin/www_bget?bta:613824", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "GKLYCTF", "url": "https://omabrowser.org/oma/group/GKLYCTF/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "G3MZ52", "url": "https://www.orthodb.org/?gene=G3MZ52", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR32344", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR32344", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR32344:SF1", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR32344:SF1", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "NP_001178066", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001178066", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "G3MZ52", "url": "https://www.uniprot.org/uniprotkb/G3MZ52", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "G3MZ52-1", "url": "https://www.uniprot.org/uniprotkb/G3MZ52-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MERFVVTAPPARNRSKTALYVTPLDRVTEFGGELHEDGGKLFCTSCNVVLNHVRKSAISDHLKSKTHTKRKAEFEEQNVRKKQRPLTASLQCNSTAQTEKVSVIQDFVKMCLEANIPLEKADHPAVRAFLSRHVKNGGSIPKSDQLRRAYLPDGYENENQLLNSQDC", "length": 167, "header": "tr|G3MZ52-1|G3MZ52_BOVIN Isoform 1 of CGG triplet repeat binding protein 1 OS=Bos taurus OX=9913 GN=CGGBP1 PE=4 SV=1 CANONICAL=G3MZ52-1" }, "isoforms": [ { "isoform_ac": "G3MZ52-1", "url": "https://www.uniprot.org/uniprotkb/G3MZ52/entry", "sequence": { "sequence": "MERFVVTAPPARNRSKTALYVTPLDRVTEFGGELHEDGGKLFCTSCNVVLNHVRKSAISDHLKSKTHTKRKAEFEEQNVRKKQRPLTASLQCNSTAQTEKVSVIQDFVKMCLEANIPLEKADHPAVRAFLSRHVKNGGSIPKSDQLRRAYLPDGYENENQLLNSQDC", "length": 167, "header": "tr|G3MZ52-1|G3MZ52_BOVIN Isoform 1 of CGG triplet repeat binding protein 1 OS=Bos taurus OX=9913 GN=CGGBP1 PE=4 SV=1 CANONICAL=G3MZ52-1" }, "locus": { "chromosome": "1", "start_pos": 36060836, "end_pos": 36060336, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000066239.3", "url": "https://www.ensembl.org/id/ENSBTAT00000066239.3" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000054844.1", "url": "https://www.ensembl.org/id/ENSBTAP00000054844.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [ { "id": "bta:613824", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?bta:613824", "resource": "KEGG Pathway" } ], "orthologs": [ { "uniprot_canonical_ac": "A0A1D5NUG1-1", "protein_name": "CGG triplet repeat binding protein 1", "gene_name": "CGGBP1", "tax_id": 9031, "organism": "Gallus gallus", "sequence": { "sequence": "MERFGVKSTPSRNRSKTALYVTPQDRVTEFGSELHEDGGKLFCTSCNVVLNHVRKSAINDHLKSKTHTKRKAEFEEQNVRKKQRTLTASLQCNSTAQTEKTSVIQDFVKMCLEANIPLEKADHPSVRAFLSRYVKNGSSIPKSEQLRKAYLPDGYDNENQLINTEDR", "length": 167 }, "evidence": [ { "id": "G3MZ52", "url": "https://omabrowser.org/oma/group/G3MZ52/", "database": "OMA" } ], "glygen_name": "Chicken", "common_name": "Chicken" }, { "uniprot_canonical_ac": "A0A287ARL7-1", "protein_name": "CGG triplet repeat binding protein 1", "gene_name": "CGGBP1", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MERFVVTAPPARNRSKTALYVTPLDRVTEFGGELHEDGGKLFCTSCNVVLNHVRKSAISDHLKSKTHTKRKAEFEEQNVRKKQRPLTASLQCNSTAQTEKVSVIQDFVKMCLEANIPLEKADHPAVRAFLSRHVKNGGSIPKSDQLRRAYLPDGYENENQLLNSQDC", "length": 167 }, "evidence": [ { "id": "G3MZ52", "url": "https://omabrowser.org/oma/group/G3MZ52/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "D4ADB4-1", "protein_name": "CGG triplet repeat binding protein 1", "gene_name": "Cggbp1", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MERFVVTAPPARNRSKTALYVTPLDRVTEFGGELHEDGGKLFCTSCNVVLNHVRKSAISDHLKSKTHTKRKAEFEEQNVRKKQRPLTASLQCNSTAQTEKVSVIQDFVKMCLEANIPLEKADHPAVRAFLSRHVKNGGSIPKSDQLRRAYLPDGYENENQLLNSQDC", "length": 167 }, "evidence": [ { "id": "G3MZ52", "url": "https://omabrowser.org/oma/group/G3MZ52/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "G3GYF2-1", "protein_name": "CGG triplet repeat-binding protein 1", "gene_name": "Cggbp1", "tax_id": 10029, "organism": "Cricetulus griseus", "sequence": { "sequence": "MERFVVTAPPARNRSKTALYVTPLDRVTEFGGELHEDGGKLFCTSCNVVLNHVRKSAISDHLKSKTHTKRKAEFEEQNVRKKQRPLTASLQCNSTAQTEKVSVIQDFVKMCLEANIPLEKADHPAVRAFLSRHVKNGGSIPKSDQLRRAYLPDGYENENQLLNSQDC", "length": 167 }, "evidence": [ { "id": "G3MZ52", "url": "https://omabrowser.org/oma/group/G3MZ52/", "database": "OMA" } ], "glygen_name": "Hamster", "common_name": "Chinese hamster" }, { "uniprot_canonical_ac": "Q8BHG9-1", "protein_name": "CGG triplet repeat-binding protein 1", "gene_name": "Cggbp1", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MERFVVTAPPARNRSKTALYVTPLDRVTEFGGELHEDGGKLFCTSCNVVLNHVRKSAISDHLKSKTHTKRKAEFEEQNVRKKQRPLTASLQCNSPAQTEKASVIQDFVKMCLEANIPLEKADHPAVRAFLSRHVKNGGSIPKSDQLRRAYLPDGYENENQLLSSQDC", "length": 167 }, "evidence": [ { "id": "G3MZ52", "url": "https://omabrowser.org/oma/group/G3MZ52/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q9UFW8-1", "protein_name": "CGG triplet repeat-binding protein 1", "gene_name": "CGGBP1", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MERFVVTAPPARNRSKTALYVTPLDRVTEFGGELHEDGGKLFCTSCNVVLNHVRKSAISDHLKSKTHTKRKAEFEEQNVRKKQRPLTASLQCNSTAQTEKVSVIQDFVKMCLEANIPLEKADHPAVRAFLSRHVKNGGSIPKSDQLRRAYLPDGYENENQLLNSQDC", "length": 167 }, "evidence": [ { "id": "G3MZ52", "url": "https://omabrowser.org/oma/group/G3MZ52/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" } ], "go_annotation": { "categories": [ { "name": "Biological Process", "total": 3, "go_terms": [ { "name": "negative regulation of transcription by RNA polymerase II", "id": "GO:0000122", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000122", "evidence": [ { "database": "UniProtKB", "id": "G3MZ52", "url": "https://www.uniprot.org/uniprotkb/G3MZ52" } ], "pmid": "" }, { "name": "regulation of gene expression", "id": "GO:0010468", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0010468", "evidence": [ { "database": "UniProtKB", "id": "G3MZ52", "url": "https://www.uniprot.org/uniprotkb/G3MZ52" } ], "pmid": "" }, { "name": "epigenetic regulation of gene expression", "id": "GO:0040029", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0040029", "evidence": [ { "database": "UniProtKB", "id": "G3MZ52", "url": "https://www.uniprot.org/uniprotkb/G3MZ52" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 2, "go_terms": [ { "name": "nucleus", "id": "GO:0005634", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005634", "evidence": [ { "database": "UniProtKB", "id": "G3MZ52", "url": "https://www.uniprot.org/uniprotkb/G3MZ52" } ], "pmid": "" }, { "name": "nucleoplasm", "id": "GO:0005654", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005654", "evidence": [ { "database": "UniProtKB", "id": "G3MZ52", "url": "https://www.uniprot.org/uniprotkb/G3MZ52" } ], "pmid": "" } ] }, { "name": "Molecular Function", "total": 3, "go_terms": [ { "name": "identical protein binding", "id": "GO:0042802", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0042802", "evidence": [ { "database": "UniProtKB", "id": "G3MZ52", "url": "https://www.uniprot.org/uniprotkb/G3MZ52" } ], "pmid": "" }, { "name": "double-stranded DNA binding", "id": "GO:0003690", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003690", "evidence": [ { "database": "UniProtKB", "id": "G3MZ52", "url": "https://www.uniprot.org/uniprotkb/G3MZ52" } ], "pmid": "" }, { "name": "DNA-binding transcription factor binding", "id": "GO:0140297", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0140297", "evidence": [ { "database": "UniProtKB", "id": "G3MZ52", "url": "https://www.uniprot.org/uniprotkb/G3MZ52" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 13, "end_pos": 15, "annotation": "n_glycosylation_sequon" }, { "start_pos": 93, "end_pos": 95, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "homologset.oma", "label": "OMA Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 13, "end_pos": 15 }, { "start_pos": 93, "end_pos": 95 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", 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{ "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ], "tool_support": { "graph_view": "yes" } }, { "uniprot_canonical_ac": "G3MZ59-1", "uniprot_ac": "G3MZ59", "uniprot_id": "G3MZ59_BOVIN", "mass": { "chemical_mass": 24822.0, "monoisotopic_mass": 24822.0 }, "refseq": { "ac": "XP_024853871", "name": "tetratricopeptide repeat protein 9A", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_024853871" }, "gene_names": [ { "name": "TTC9", "type": "recommended", "evidence": [ { "id": "G3MZ59", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3MZ59" } ] }, { "name": "TTC9", "type": "synonym", "evidence": [ { "id": "XP_024853871", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_024853871" } ] } ], "protein_names": [ { "name": "Tetratricopeptide repeat protein 9A", "type": "recommended", "evidence": [ { "id": "G3MZ59", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3MZ59/entry#names_and_taxonomy" } ] }, { "name": "tetratricopeptide repeat protein 9A", "type": "synonym", "evidence": [ { "id": "XP_024853871", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_024853871" } ] } ], "function": [], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Bos taurus", "taxid": 9913, "evidence": [ { "database": "UniProtKB", "id": "G3MZ59", "url": "https://www.uniprot.org/uniprotkb/G3MZ59" } ], "common_name": "Bovine", "glygen_name": "Bovine", "reference_species": "Bos taurus [9913]" } ], "gene": [ { "name": "TTC9", "url": "https://www.uniprot.org/uniprotkb/G3MZ59", "locus": { "chromosome": "10", "start_pos": 82314429, "end_pos": 82281268, "strand": "-", "evidence": [ { "database": "Ensembl Gene", "id": "ENSBTAG00000045604", "url": "https://www.ensembl.org/id/ENSBTAG00000045604" } ] } } ], "crossref": [ { "id": "G3MZ59", "url": "https://alphafold.ebi.ac.uk/entry/G3MZ59", "database": "AlphaFoldDB", "categories": [] }, { "id": "ENSBTAG00000045604", "url": "https://bgee.org/?page=gene&gene_id=ENSBTAG00000045604", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "523451", "url": "https://www.ncbi.nlm.nih.gov/gene/523451", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR011990", "url": "https://www.ebi.ac.uk/interpro/entry/IPR011990", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR019734", "url": "https://www.ebi.ac.uk/interpro/entry/IPR019734", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR050754", "url": "https://www.ebi.ac.uk/interpro/entry/IPR050754", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "bta:523451", "url": "https://www.genome.jp/dbget-bin/www_bget?bta:523451", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "RSSGCGQ", "url": "https://omabrowser.org/oma/group/RSSGCGQ/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "G3MZ59", "url": "https://www.orthodb.org/?gene=G3MZ59", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR46512", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR46512", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR46512:SF5", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR46512:SF5", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00515", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00515", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "XP_024853871", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_024853871", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "G3MZ59", "url": "https://www.uniprot.org/uniprotkb/G3MZ59", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "G3MZ59-1", "url": "https://www.uniprot.org/uniprotkb/G3MZ59-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MERKGSAAGAKGNPSPPAAGEAQRPQPPLCVPGGGGGGGGGGGGGTPARGQAGAAAEPAEFIRRAHEFKSQGAQCYKDKKFREAIGKYHRALLELKGLLPAAGERERDSRGASPAGAPNPGRLSEEQSKTVEAIEIDCYNSLAACLLQAELVNYERVKEYCLKVLKKEGENFKALYRSGVAFYHLGDYDKALYYLKEARTRQPTDTNVIRYIQLTEMKLSRCSQREKEAM", "length": 230, "header": "tr|G3MZ59-1|G3MZ59_BOVIN Isoform 1 of Tetratricopeptide repeat protein 9A OS=Bos taurus OX=9913 GN=TTC9 PE=3 SV=2 CANONICAL=G3MZ59-1" }, "isoforms": [ { "isoform_ac": "G3MZ59-1", "url": "https://www.uniprot.org/uniprotkb/G3MZ59/entry", "sequence": { "sequence": "MERKGSAAGAKGNPSPPAAGEAQRPQPPLCVPGGGGGGGGGGGGGTPARGQAGAAAEPAEFIRRAHEFKSQGAQCYKDKKFREAIGKYHRALLELKGLLPAAGERERDSRGASPAGAPNPGRLSEEQSKTVEAIEIDCYNSLAACLLQAELVNYERVKEYCLKVLKKEGENFKALYRSGVAFYHLGDYDKALYYLKEARTRQPTDTNVIRYIQLTEMKLSRCSQREKEAM", "length": 230, "header": "tr|G3MZ59-1|G3MZ59_BOVIN Isoform 1 of Tetratricopeptide repeat protein 9A OS=Bos taurus OX=9913 GN=TTC9 PE=3 SV=2 CANONICAL=G3MZ59-1" }, "locus": { "chromosome": "10", "start_pos": 82313425, "end_pos": 82281701, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000064762.4", "url": "https://www.ensembl.org/id/ENSBTAT00000064762.4" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000054852.2", "url": "https://www.ensembl.org/id/ENSBTAP00000054852.2" } ] } } ], "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "other", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 46, "start_aa": "Thr", "end_pos": 46, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr46", "evidence": [ { "id": "", "database": "GlyGen", "url": "https://data.glygen.org/" } ], "filter_code": "000000000000000010000.00000000001000.0.01000" } ], "phosphorylation": [], "glycation": [], "keywords": [ "glycoprotein", "glycoprotein_predicted" ], "publication": [], "pathway": [ { "id": "bta:523451", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?bta:523451", "resource": "KEGG Pathway" } ], "orthologs": [ { "uniprot_canonical_ac": "F1S497-1", "protein_name": "Tetratricopeptide repeat protein 9A", "gene_name": "TTC9", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MERKGSAAGAKGNPSPPAAGEAQRPQPPLCVPGGSGGTPARGQAGAAAEPAEFIRRAHEFKSQGAQCYKDKKFREAIGKYHRALLELKGLLPAAGERERDSRSASPAGAPNPGRLSEEQSKTVEAIEIDCYNSLAACLLQAELVNYERVKEYCLKVLKKEGENFKALYRSGVAFYHLGDYDKALYYLKEARTRQPTDTNVIRYIQLTEMKLSRCSQREKEAM", "length": 222 }, "evidence": [ { "id": "G3MZ59", "url": "https://omabrowser.org/oma/group/G3MZ59/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "Q3V038-1", "protein_name": "Tetratricopeptide repeat protein 9A", "gene_name": "Ttc9", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MERKGLAARSSGNPSPPALGEGPRPVPPPCVPSGGGAPERGQAGTAAEPAELIRRAHEFKSQGAQCYKDKKFREAIGKYHRALLELKGLLPSQEERDARPASSAGVPKSSRLSEEQSKTVEAIEIDCYNSLAACLLQAELVNYERVKEYCLKVLKKEGENFKALYRSGVAFYHLGDYDKALYYLKEARTRQPTDTNVIRYIQLTEMKLSRCSQREKEAM", "length": 219 }, "evidence": [ { "id": "G3MZ59", "url": "https://omabrowser.org/oma/group/G3MZ59/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q92623-1", "protein_name": "Tetratricopeptide repeat protein 9A", "gene_name": "TTC9", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MERKGSAAGAKGNPSPPAAGEGQRPPPPLCVPGGGGGAPARGQVGAAAEPAELIRRAHEFKSQGAQCYKDKKFREAIGKYHRALLELKGLLPPPGERERDSRPASPAGALKPGRLSEEQSKTVEAIEIDCYNSLAACLLQAELVNYERVKEYCLKVLKKEGENFKALYRSGVAFYHLGDYDKALYYLKEARTQQPTDTNVIRYIQLTEMKLSRCSQREKEAM", "length": 222 }, "evidence": [ { "id": "G3MZ59", "url": "https://omabrowser.org/oma/group/G3MZ59/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" } ], "go_annotation": {}, "pro_annotation": [], "site_annotation": [], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [ { "pdb_id": "AF-G3MZ59-F1", "pdb_chain": "global", "start_pos": 1, "end_pos": 230, "overlap": "1.0", "method": "AlphaFold", "type": "alphafold", "resolution": -1.0, "url": "https://data.glygen.org/ln2downloads/pdb/current/AF-G3MZ59-F1.pdb", "url_external": "https://alphafold.ebi.ac.uk/entry/G3MZ59" } ], "lectin_list": [], "domain_list": [], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "homologset.oma", "label": "OMA Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [ 46 ], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 1 }, { "field": "total_sites", "count": 1 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 1 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "exact_sites", "count": 1 }, { "field": 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"phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [ { "id": "bta:616869", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?bta:616869", "resource": "KEGG Pathway" } ], "orthologs": [ { "uniprot_canonical_ac": "Q8N878-1", "protein_name": "FERM domain-containing protein 1", "gene_name": "FRMD1", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MAVPPRGRGIDPARTNPDTFPPSGARCMEPSPERPACSQQEPTLGMDAMASEHRDVLVLLPSREQLRLAVGVKATGRELFQQVCNVASIRDAQFFGLCVVRNNEYIFMDLEQKLSKYFSKDWKKERNEGNEKPRAPFVAFLRVQHYVENGRVISDHRARHLYYCHLKERVLRSQCAHREEAYFLLAACALQADLGEHRESAHAGRYFEPHSYFPQWIITKRGIDYILRHMPTLHRERQGLSPKEAMLCFIQEACRLEDVPVHFFRLHKDKKEGRPTVILGLALRGVHIYQGKKLEIQLDGLPAAQKLVYYTGCTWRSRHLLHLLRASHQLHLRVRPTLQQLRQREEAEEKQHYRESYISDELELDLASRSFPGSGVSSQHCPHCLSRHSADSHGSSYTSGIKANSWLRESREMSVDVPLEVHGLHEKEPSSSPRTSRSHPSTRGDSQATRQEPCTQVRTRGQSAEAVHQIQEMTAGVSEEQHSHGLDDMQLHQLALHPAPTSLSHTFHRALDCRLAGPCETRATLPSKRSSNCLALDLFGEAPPQEFVV", "length": 549 }, "evidence": [ { "id": "G3MZ72", "url": "https://omabrowser.org/oma/group/G3MZ72/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" } ], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 2, "go_terms": [ { "name": "plasma membrane", "id": "GO:0005886", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005886", "evidence": [ { "database": "UniProtKB", "id": "G3MZ72", "url": "https://www.uniprot.org/uniprotkb/G3MZ72" } ], "pmid": "" }, { "name": "cell-cell junction", "id": "GO:0005911", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005911", "evidence": [ { "database": "UniProtKB", "id": "G3MZ72", "url": "https://www.uniprot.org/uniprotkb/G3MZ72" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 1, "go_terms": [ { "name": "positive regulation of hippo signaling", "id": "GO:0035332", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0035332", "evidence": [ { "database": "UniProtKB", "id": "G3MZ72", "url": "https://www.uniprot.org/uniprotkb/G3MZ72" } ], "pmid": "" } ] }, { "name": "Molecular Function", "total": 1, "go_terms": [ { "name": "protein sequestering activity", "id": "GO:0140311", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0140311", "evidence": [ { "database": "UniProtKB", "id": "G3MZ72", "url": "https://www.uniprot.org/uniprotkb/G3MZ72" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 245, "end_pos": 247, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [ { "pdb_id": "AF-G3MZ72-F1", "pdb_chain": "global", "start_pos": 1, "end_pos": 443, "overlap": "1.0", "method": "AlphaFold", "type": "alphafold", "resolution": -1.0, "url": "https://data.glygen.org/ln2downloads/pdb/current/AF-G3MZ72-F1.pdb", "url_external": "https://alphafold.ebi.ac.uk/entry/G3MZ72" } ], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "G3MZ72", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3MZ72" }, { "id": "PS50057", "database": "PROSITE", "url": "https://prosite.expasy.org/PS50057" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "FERM", "eco_id": "ECO_0000259", "start_pos": 6, "end_pos": 310, "start_aa": "Arg", "end_aa": "Gln", "glycosite_overlap": [] } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "homologset.oma", "label": "OMA Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 245, "end_pos": 247 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ], "tool_support": { "graph_view": "yes" } }, { "uniprot_canonical_ac": "G3MZ75-1", "uniprot_ac": "G3MZ75", "uniprot_id": "G3MZ75_BOVIN", "mass": { "chemical_mass": 35635.0, "monoisotopic_mass": 35635.0 }, "refseq": { "ac": "XP_024838004", "name": "transmembrane protein 121", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_024838004" }, "gene_names": [ { "name": "TMEM121", "type": "recommended", "evidence": [ { "id": "G3MZ75", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3MZ75" } ] }, { "name": "TMEM121", "type": "synonym", "evidence": [ { "id": "XP_024838004", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_024838004" } ] } ], "protein_names": [ { "name": "Transmembrane protein 121", "type": "synonym", "evidence": [ { "id": "G3MZ75", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3MZ75/entry#names_and_taxonomy" } ] }, { "name": "transmembrane protein 121", "type": "synonym", "evidence": [ { "id": "XP_024838004", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_024838004" } ] } ], "function": [], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Bos taurus", "taxid": 9913, "evidence": [ { "database": "UniProtKB", "id": "G3MZ75", "url": "https://www.uniprot.org/uniprotkb/G3MZ75" } ], "common_name": "Bovine", "glygen_name": "Bovine", "reference_species": "Bos taurus [9913]" } ], "gene": [ { "name": "TMEM121", "url": "https://www.uniprot.org/uniprotkb/G3MZ75", "locus": { "chromosome": "21", "start_pos": 69784994, "end_pos": 69783581, "strand": "-", "evidence": [ { "database": "Ensembl Gene", "id": "ENSBTAG00000045594", "url": "https://www.ensembl.org/id/ENSBTAG00000045594" } ] } } ], "crossref": [ { "id": "ENSBTAG00000045594", "url": "https://bgee.org/?page=gene&gene_id=ENSBTAG00000045594", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "112443183", "url": "https://www.ncbi.nlm.nih.gov/gene/112443183", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR032776", "url": "https://www.ebi.ac.uk/interpro/entry/IPR032776", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR042314", "url": "https://www.ebi.ac.uk/interpro/entry/IPR042314", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "bta:112443183", "url": "https://www.genome.jp/dbget-bin/www_bget?bta:112443183", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "QATLWEP", "url": "https://omabrowser.org/oma/group/QATLWEP/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "G3MZ75", "url": "https://www.orthodb.org/?gene=G3MZ75", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR31046", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR31046", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR31046:SF0", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR31046:SF0", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF14997", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF14997", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "XP_024838004", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_024838004", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "G3MZ75", "url": "https://www.uniprot.org/uniprotkb/G3MZ75", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "G3MZ75-1", "url": "https://www.uniprot.org/uniprotkb/G3MZ75-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MVLPPPDRRHVCLTTLVIMGSMAVMDAYLVEQNQGPRKIGVCIIVLVGDVCFLLVLRYVAVWVGAEVRTAKRGYAMILWFLYIFVLEIKLYFIFQNYKAARRGAADPVARKALTLLLSVCVPGLFLLLVALDRMEYVRTFRKREDLRGRLFWVALDLLDLLDMQASLWEPPRSGLPLWAEGLTFFYCYMLLLVLPCVALSEVSMQGEHIAPQKMMLYPVLSLATVNVVAVLARAANMALFRDSRVSAIFVGKNVVALATKACTFLEYRRQVRDFPPPALALELQPPAPQRNSVPPPQPLHGPPGRPRGPSPTRDALDT", "length": 318, "header": "tr|G3MZ75-1|G3MZ75_BOVIN Isoform 1 of Transmembrane protein 121 OS=Bos taurus OX=9913 GN=TMEM121 PE=3 SV=1 CANONICAL=G3MZ75-1" }, "isoforms": [ { "isoform_ac": "G3MZ75-1", "url": "https://www.uniprot.org/uniprotkb/G3MZ75/entry", "sequence": { "sequence": "MVLPPPDRRHVCLTTLVIMGSMAVMDAYLVEQNQGPRKIGVCIIVLVGDVCFLLVLRYVAVWVGAEVRTAKRGYAMILWFLYIFVLEIKLYFIFQNYKAARRGAADPVARKALTLLLSVCVPGLFLLLVALDRMEYVRTFRKREDLRGRLFWVALDLLDLLDMQASLWEPPRSGLPLWAEGLTFFYCYMLLLVLPCVALSEVSMQGEHIAPQKMMLYPVLSLATVNVVAVLARAANMALFRDSRVSAIFVGKNVVALATKACTFLEYRRQVRDFPPPALALELQPPAPQRNSVPPPQPLHGPPGRPRGPSPTRDALDT", "length": 318, "header": "tr|G3MZ75-1|G3MZ75_BOVIN Isoform 1 of Transmembrane protein 121 OS=Bos taurus OX=9913 GN=TMEM121 PE=3 SV=1 CANONICAL=G3MZ75-1" }, "locus": { "chromosome": "21", "start_pos": 69784581, "end_pos": 69783628, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000063139.3", "url": "https://www.ensembl.org/id/ENSBTAT00000063139.3" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000054869.1", "url": "https://www.ensembl.org/id/ENSBTAP00000054869.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [ { "id": "bta:112443183", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?bta:112443183", "resource": "KEGG Pathway" } ], "orthologs": [ { "uniprot_canonical_ac": "A0A9J7G001-1", "protein_name": "Transmembrane protein 121 isoform X2", "gene_name": "Tmem121", "tax_id": 10029, "organism": "Cricetulus griseus", "sequence": { "sequence": "MRTNGSELAGQERQRAPGSWTNPAPGCAAPCRRVECRGRCSGTQQDLVPLCVGTARARAEPGPLTMVLPPPDRRHVCLTTLVIMGSMAVMDAYLVEQNQGPRKIGVCIIVLVGDVCFLLVLRYVAVWVGAEVRTAKRGYAMILWFLYIFVLEIKLYFIFQNYKAARRGAADPVARKALTLLLSVCVPGLFLLLVALDRMEYVRTFRKREDLRGRLFWVALDLLDLLDMQANLWEPPRTGLPLWAEGLTFFYCYMLLLVLPCVALSEVSMQGEHIAPQKMMLYPVLSLATVNVVAVLARAANMALFRDSRVSAIFVGKNVVALATKACTFLEYRRQVRDFPPPALALELQPPPSQRNSVPPPAPLHGPPVRPHGPSPTRDALDT", "length": 383 }, "evidence": [ { "id": "G3MZ75", "url": "https://omabrowser.org/oma/group/G3MZ75/", "database": "OMA" } ], "glygen_name": "Hamster", "common_name": "Chinese hamster" }, { "uniprot_canonical_ac": "D3ZMR5-1", "protein_name": "Transmembrane protein 121", "gene_name": "Tmem121", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MVLPPPDRRHVCLTTLVIMGSMAVMDAYLVEQNQGPRKIGVCIIVLVGDVCFLLVLRYVAVWVGAEVRTAKRGYAMILWFLYIFVLEIKLYFIFQNYKAARRGAADPVARKALTLLLSVCVPGLFLLLVALDRMEYVRTFRKREDLRGRLFWVALDLLDLLDMQANLWEPPRTGLPLWAEGLTFFYCYMLLLVLPCVALSEVSMQGEHIAPQKMMLYPVLSLATVNVVAVLARAANMALFRDSRVSAIFVGKNVVALATKACTFLEYRRQVRDFPPPALALELQPPPSQRNSVPPPPPLHGPPVRPHGPSPTRDALDT", "length": 318 }, "evidence": [ { "id": "G3MZ75", "url": "https://omabrowser.org/oma/group/G3MZ75/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "E7F5Q9-1", "protein_name": "Transmembrane protein 121", "gene_name": "tmem121aa", "tax_id": 7955, "organism": "Danio rerio", "sequence": { "sequence": "MVLPPPDKRHVCLTTIVIMTSMAFMDAYLVEQNQGPRKIGVCIIVLVGDICFLIVLRYVAVWVGAEVRTAKRGYAMILWFLYIFVLEIKLYFVFQNYKADRKSLETVARKALTLLLSVCVPGLYLVLVALDSMEYVRTFRKKEDMRGRLFWVALDLLDVLDIQANLWEPQRTGLPIWAEGLMFFYCYILLLILPCVSLSEISVQGEHVSPQKMMLYPVLSLVTINIVTILIRGVNMVLFQDSRVSTIFIGKNVVAIATKACTFLEYRRQVKEFPPQDPAGIAMEIQQNSVPHNQTLPNATTTLPEEPSPAREVIDT", "length": 316 }, "evidence": [ { "id": "G3MZ75", "url": "https://omabrowser.org/oma/group/G3MZ75/", "database": "OMA" } ], "glygen_name": "Zebrafish", "common_name": "Zebrafish" }, { "uniprot_canonical_ac": "K7ZLB0-1", "protein_name": "Transmembrane protein 121", "gene_name": "TMEM121", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MVLPPPDRRHVCLTTLVIMGSMAVMDAYLVEQNQGPRKIGVCIIVLVGDVCFLLVLRYVAVWVGAEVRTAKRGYAMILWFLYIFVLEIKLYFIFQNYKAARRGAADPVARKALTLLLSVCVPGLFLLLVALDRMEYVRTFRKREDLRGRLFWVALDLLDLLDMQANLWEPPRTGLPLWAEGLTFFYCYMLLLVLPCVALSEVSMQGEHIAPQKMMLYPVLSLATVNVVAVLARAANMALFRDSRVSAIFVGKNVVALATKACTFLEYRRQVRDFPPPALALELQPPPPQRNSVPPPPPLHGPPGRPHGPSPTRDALDT", "length": 318 }, "evidence": [ { "id": "G3MZ75", "url": "https://omabrowser.org/oma/group/G3MZ75/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "Q80XA0-1", "protein_name": "Transmembrane protein 121", "gene_name": "Tmem121", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MVLPPPDRRHVCLTTLVIMGSMAVMDAYLVEQNQGPRKIGVCIIVLVGDVCFLLVLRYVAVWVGAEVRTAKRGYAMILWFLYIFVLEIKLYFIFQNYKAARRGAADPVARKALTLLLSVCVPGLFLLLVALDRMEYVRTFRKREDLRGRLFWVALDLLDLLDMQANLWEPPRTGLPLWAEGLTFFYCYMLLLVLPCVALSEVSMQGEHIAPQKMMLYPVLSLATVNVVAVLARAANMALFRDSRVSAIFVGKNVVALATKACTFLEYRRQVRDFPPPALALELQPPPSQRNSVPPPPPLHGPPVRPHGPSPTRDALDT", "length": 318 }, "evidence": [ { "id": "G3MZ75", "url": "https://omabrowser.org/oma/group/G3MZ75/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q8QFN3-1", "protein_name": "Transmembrane protein 121", "gene_name": "TMEM121", "tax_id": 9031, "organism": "Gallus gallus", "sequence": { "sequence": "MVLPPPDKRHVCLTTIVIMTSMAFMDAYLVEQNQGPRKIGVCIIVLVGDICFLIVLRYVAVWVGAEVKTAKRGYAMILWFLYIFVLEIKLYFIFQNYKADKKNLETVARKALTLLLSICVPGLYLVLVALDSMEYIRTFRKKEDLRGRLFWVALDLLDILDIQANLWEPHRTGLPIWAEGLMFFYCYILLLILPCVSLSEISMQGEHIAPQKMMLYPVLSLVTINIVTIFIRAINMVLFQDSRVSTIFIGKNIIAIATKACTFLEYKRQVKEFPQNAIALELQQNSLSHNQTLHSTQGIPHEPSPTSEILDT", "length": 312 }, "evidence": [ { "id": "G3MZ75", "url": "https://omabrowser.org/oma/group/G3MZ75/", "database": "OMA" } ], "glygen_name": "Chicken", "common_name": "Chicken" }, { "uniprot_canonical_ac": "Q9BTD3-1", "protein_name": "Transmembrane protein 121", "gene_name": "TMEM121", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": 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The olfactory receptor proteins are members of a large family of G-protein-coupled receptors (GPCR) arising from single coding-exon genes. Olfactory receptors share a 7-transmembrane domain structure with many neurotransmitter and hormone receptors and are responsible for the recognition and G protein-mediated transduction of odorant signals. The olfactory receptor gene family is the largest in the genome. [provided by RefSeq, Jul 2008].", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001376907" }, "gene_names": [ { "name": "OR4N4", "type": "recommended", "evidence": [ { "id": "G3MZ76", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3MZ76" } ] }, { "name": "OR4N2", "type": "synonym", "evidence": [ { "id": "NP_001376907", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001376907" } ] }, { "name": "OR4N4", "type": "synonym", "evidence": [ { "id": "NP_001376907", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001376907" } ] } ], "protein_names": [ { "name": "Olfactory receptor family 4 subfamily N member 4", "type": "synonym", "evidence": [ { "id": "G3MZ76", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3MZ76/entry#names_and_taxonomy" } ] }, { "name": "olfactory receptor family 4 subfamily N member 4", "type": "synonym", "evidence": [ { "id": "NP_001376907", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001376907" } ] }, { "name": "olfactory receptor, family 4, subfamily N, member 2", "type": "synonym", "evidence": [ { "id": "NP_001376907", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001376907" } ] } ], "function": [ { "annotation": "Olfactory receptors interact with odorant molecules in the nose, to initiate a neuronal response that triggers the perception of a smell. The olfactory receptor proteins are members of a large family of G-protein-coupled receptors (GPCR) arising from single coding-exon genes. Olfactory receptors share a 7-transmembrane domain structure with many neurotransmitter and hormone receptors and are responsible for the recognition and G protein-mediated transduction of odorant signals. The olfactory receptor gene family is the largest in the genome. [provided by RefSeq, Jul 2008].", "evidence": [ { "database": "RefSeq", "id": "NP_001376907", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001376907" } ] }, { "annotation": "Putative odorant or sperm cell receptor.", "evidence": [ { "database": "UniProtKB", "id": "G3MZ76", "url": "https://www.uniprot.org/uniprotkb/G3MZ76#function" }, { "database": "UniProtKB", "id": "ARBA00003929", "url": "https://www.uniprot.org/uniprotkb/ARBA00003929#function" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Bos taurus", "taxid": 9913, "evidence": [ { "database": "UniProtKB", "id": "G3MZ76", "url": "https://www.uniprot.org/uniprotkb/G3MZ76" } ], "common_name": "Bovine", "glygen_name": "Bovine", "reference_species": "Bos taurus [9913]" } ], "gene": [ { "name": "OR4N4", "url": "https://www.uniprot.org/uniprotkb/G3MZ76", "locus": { "chromosome": "10", "start_pos": 27215183, "end_pos": 27214257, "strand": "-", "evidence": [ { "database": "Ensembl Gene", "id": "ENSBTAG00000060021", "url": "https://www.ensembl.org/id/ENSBTAG00000060021" } ] } } ], "crossref": [ { "id": "G3MZ76", "url": "https://alphafold.ebi.ac.uk/entry/G3MZ76", "database": "AlphaFoldDB", "categories": [] }, { "id": "ENSBTAG00000054809", "url": "https://bgee.org/?page=gene&gene_id=ENSBTAG00000054809", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "515867", "url": "https://www.ncbi.nlm.nih.gov/gene/515867", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR000276", "url": "https://www.ebi.ac.uk/interpro/entry/IPR000276", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR000725", "url": "https://www.ebi.ac.uk/interpro/entry/IPR000725", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR017452", "url": "https://www.ebi.ac.uk/interpro/entry/IPR017452", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR050427", "url": "https://www.ebi.ac.uk/interpro/entry/IPR050427", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "bta:515867", "url": "https://www.genome.jp/dbget-bin/www_bget?bta:515867", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "CHVRRTA", "url": "https://omabrowser.org/oma/group/CHVRRTA/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "G3MZ76", "url": "https://www.orthodb.org/?gene=G3MZ76", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR48002", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR48002", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF13853", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF13853", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "NP_001376907", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001376907", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "G3MZ76", "url": "https://www.uniprot.org/uniprotkb/G3MZ76", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "G3MZ76-1", "url": "https://www.uniprot.org/uniprotkb/G3MZ76-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MERENSTVVTEFILAGLTQSQDVQLLVFTLVLIFYLIILPGNFLIILTIRSDPSLTAPLYFFLGNLAFLDASYSFIVAPRMLVDFLSEKKVISYRGCITQLFFLHFLGGGEMLLLNVMAFDPYIAICRPLHYSTVMNPRACYALLLALWLGGFVHSIIQVALILCLPFCGPNRLDNFFCDVPQVIKLACTDTFVVELLMVFNSGLLTLLCFLGLLASYAVILCRVHGSSSEGKSKALSMCTTHVIIILLMFGPAIFIYTRPFTALSADKVVSFFHTVIFPLMNPVIYTLRNQEVKASMRKILSQHMVC", "length": 308, "header": "tr|G3MZ76-1|G3MZ76_BOVIN Isoform 1 of Olfactory receptor family 4 subfamily N member 4 OS=Bos taurus OX=9913 GN=OR4N4 PE=3 SV=1 CANONICAL=G3MZ76-1" }, "isoforms": [ { "isoform_ac": "G3MZ76-1", "url": "https://www.uniprot.org/uniprotkb/G3MZ76/entry", "sequence": { "sequence": 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"evidence": [ { "id": "G3MZ76", "url": "https://omabrowser.org/oma/group/G3MZ76/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" } ], "go_annotation": { "categories": [ { "name": "Molecular Function", "total": 2, "go_terms": [ { "name": "G protein-coupled receptor activity", "id": "GO:0004930", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0004930", "evidence": [ { "database": "UniProtKB", "id": "G3MZ76", "url": "https://www.uniprot.org/uniprotkb/G3MZ76" } ], "pmid": "" }, { "name": "olfactory receptor activity", "id": "GO:0004984", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0004984", "evidence": [ { "database": "UniProtKB", "id": "G3MZ76", "url": "https://www.uniprot.org/uniprotkb/G3MZ76" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 1, "go_terms": [ { "name": "plasma membrane", "id": "GO:0005886", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005886", "evidence": [ { "database": "UniProtKB", "id": "G3MZ76", "url": 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"uniprot_id": "G3MZ83_BOVIN", "mass": { "chemical_mass": 49659.0, "monoisotopic_mass": 49659.0 }, "refseq": {}, "gene_names": [], "protein_names": [ { "name": "Polyadenylate-binding protein-interacting protein 1", "type": "recommended", "evidence": [ { "id": "G3MZ83", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3MZ83/entry#names_and_taxonomy" } ] } ], "function": [ { "annotation": "Acts as a coactivator in the regulation of translation initiation of poly(A)-containing mRNAs. Its stimulatory activity on translation is mediated via its action on PABPC1. Competes with PAIP2 for binding to PABPC1. Its association with EIF4A and PABPC1 may potentiate contacts between mRNA termini. May also be involved in translationally coupled mRNA turnover. Implicated with other RNA-binding proteins in the cytoplasmic deadenylation/translational and decay interplay of the FOS mRNA mediated by the major coding-region determinant of instability (mCRD) domain.", "evidence": [ { "database": "UniProtKB", "id": "G3MZ83", "url": "https://www.uniprot.org/uniprotkb/G3MZ83#function" }, { "database": "UniProtKB", "id": "ARBA00053366", "url": "https://www.uniprot.org/uniprotkb/ARBA00053366#function" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Bos taurus", "taxid": 9913, "evidence": [ { "database": "UniProtKB", "id": "G3MZ83", "url": "https://www.uniprot.org/uniprotkb/G3MZ83" } ], "common_name": "Bovine", "glygen_name": "Bovine", "reference_species": "Bos taurus [9913]" } ], "gene": [ { "name": "", "url": "https://www.uniprot.org/uniprotkb/G3MZ83", "locus": {} } ], "crossref": [ { "id": "G3MZ83", "url": "https://alphafold.ebi.ac.uk/entry/G3MZ83", "database": "AlphaFoldDB", "categories": [] }, { "id": "ENSBTAG00000046231", "url": "https://bgee.org/?page=gene&gene_id=ENSBTAG00000046231", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "IPR003890", "url": "https://www.ebi.ac.uk/interpro/entry/IPR003890", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR009818", "url": "https://www.ebi.ac.uk/interpro/entry/IPR009818", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR016024", "url": "https://www.ebi.ac.uk/interpro/entry/IPR016024", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR051367", "url": "https://www.ebi.ac.uk/interpro/entry/IPR051367", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "PTHR23254", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR23254", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR23254:SF15", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR23254:SF15", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF02854", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF02854", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF07145", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF07145", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "G3MZ83", "url": "https://www.uniprot.org/uniprotkb/G3MZ83", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "G3MZ83-1", "url": "https://www.uniprot.org/uniprotkb/G3MZ83-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MSDGFDRAPGAGLGRSWGLGRGGGGPEGSGFLKGAGPAELPCHQPPPPPQPKAPDFLQPPPLCQTRTAPPPGAECEVPAGPQRPARPGALPEQTRPLRGPSSSPDNITQQNSQSAMAKPQVAVAPVLMSKLSVNAPEFYPSSYFSNYTESYEDGFEDYPTLSEYVQDFLNHLTEQPGNFETEIGQFAETLNGWVTTDDALQQLVELIYQQATSIPNFSYMGARLCNYLCHHLTINPQSGSFRQLLLQRCRTEYEVKDQAAKGDEVTRKRFHAFVLFLGELYLNLEIKGTNGQVARADILQTGLRELLNALFSNPMDDNLICAVKLLKLTGSVLEDGWKEKGKTDMKEIIQRIENVVLDANCSRDVKQMLLKLVELWSSNWGRVHAITKRNIKSYLKEKTFFPDYEENGTDLSGGGDPSLDDIDDEMDPEIEEAYEKFCLEPERKRKQ", "length": 447, "header": "tr|G3MZ83-1|G3MZ83_BOVIN Isoform 1 of Polyadenylate-binding protein-interacting protein 1 OS=Bos taurus OX=9913 GN= PE=4 SV=3 CANONICAL=G3MZ83-1" }, "isoforms": [ { "isoform_ac": "G3MZ83-1", "url": "https://www.uniprot.org/uniprotkb/G3MZ83/entry", "sequence": { "sequence": "MSDGFDRAPGAGLGRSWGLGRGGGGPEGSGFLKGAGPAELPCHQPPPPPQPKAPDFLQPPPLCQTRTAPPPGAECEVPAGPQRPARPGALPEQTRPLRGPSSSPDNITQQNSQSAMAKPQVAVAPVLMSKLSVNAPEFYPSSYFSNYTESYEDGFEDYPTLSEYVQDFLNHLTEQPGNFETEIGQFAETLNGWVTTDDALQQLVELIYQQATSIPNFSYMGARLCNYLCHHLTINPQSGSFRQLLLQRCRTEYEVKDQAAKGDEVTRKRFHAFVLFLGELYLNLEIKGTNGQVARADILQTGLRELLNALFSNPMDDNLICAVKLLKLTGSVLEDGWKEKGKTDMKEIIQRIENVVLDANCSRDVKQMLLKLVELWSSNWGRVHAITKRNIKSYLKEKTFFPDYEENGTDLSGGGDPSLDDIDDEMDPEIEEAYEKFCLEPERKRKQ", "length": 447, "header": "tr|G3MZ83-1|G3MZ83_BOVIN Isoform 1 of Polyadenylate-binding protein-interacting protein 1 OS=Bos taurus OX=9913 GN= PE=4 SV=3 CANONICAL=G3MZ83-1" }, "locus": { "chromosome": "3", "start_pos": 8695554, "end_pos": 8694108, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000063090.3", "url": "https://www.ensembl.org/id/ENSBTAT00000063090.3" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000054878.3", "url": "https://www.ensembl.org/id/ENSBTAP00000054878.3" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [], "orthologs": [], "go_annotation": { "categories": [ { "name": "Molecular Function", "total": 2, "go_terms": [ { "name": "RNA binding", "id": "GO:0003723", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003723", "evidence": [ { "database": "UniProtKB", "id": "G3MZ83", "url": "https://www.uniprot.org/uniprotkb/G3MZ83" } ], "pmid": "" }, { "name": "translation activator activity", "id": "GO:0008494", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008494", "evidence": [ { "database": "UniProtKB", "id": "G3MZ83", "url": "https://www.uniprot.org/uniprotkb/G3MZ83" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 1, "go_terms": [ { "name": "cytoplasm", "id": "GO:0005737", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005737", "evidence": [ { "database": "UniProtKB", "id": "G3MZ83", "url": "https://www.uniprot.org/uniprotkb/G3MZ83" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 1, "go_terms": [ { "name": "regulation of translational initiation", "id": "GO:0006446", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006446", "evidence": [ { "database": "UniProtKB", "id": "G3MZ83", "url": "https://www.uniprot.org/uniprotkb/G3MZ83" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 106, "end_pos": 108, "annotation": "n_glycosylation_sequon" }, { "start_pos": 146, "end_pos": 148, "annotation": "n_glycosylation_sequon" }, { "start_pos": 216, "end_pos": 218, "annotation": "n_glycosylation_sequon" }, { "start_pos": 360, "end_pos": 362, "annotation": "n_glycosylation_sequon" }, { "start_pos": 407, "end_pos": 409, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [ { "pdb_id": "AF-G3MZ83-F1", "pdb_chain": "global", "start_pos": 1, "end_pos": 447, "overlap": "1.0", "method": "AlphaFold", "type": "alphafold", "resolution": -1.0, "url": "https://data.glygen.org/ln2downloads/pdb/current/AF-G3MZ83-F1.pdb", "url_external": "https://alphafold.ebi.ac.uk/entry/G3MZ83" } ], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "G3MZ83", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3MZ83" }, { "id": "SM00543", "database": "SMART", "url": "http://smart.embl.de/smart/do_annotation.pl?DOMAIN=SM00543" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "MIF4G", "eco_id": "ECO_0000259", "start_pos": 162, "end_pos": 379, "start_aa": "Ser", "end_aa": "Asn", "glycosite_overlap": [] } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 106, "end_pos": 108 }, { "start_pos": 146, "end_pos": 148 }, { "start_pos": 216, "end_pos": 218 }, { "start_pos": 360, "end_pos": 362 }, { "start_pos": 407, "end_pos": 409 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ], "tool_support": { "graph_view": "yes" } }, { "uniprot_canonical_ac": "G3MZA6-1", "uniprot_ac": "G3MZA6", "uniprot_id": "G3MZA6_BOVIN", "mass": { "chemical_mass": 103544.0, "monoisotopic_mass": 103544.0 }, "refseq": { "ac": "NP_001192831", "name": "protein SLFN14", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001192831" }, "gene_names": [ { "name": "SLFN14", "type": "recommended", "evidence": [ { "id": "G3MZA6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3MZA6" } ] }, { "name": "SLFN14", "type": "synonym", "evidence": [ { "id": "NP_001192831", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001192831" } ] } ], "protein_names": [ { "name": "Schlafen family member 14", "type": "synonym", "evidence": [ { "id": "G3MZA6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3MZA6/entry#names_and_taxonomy" } ] }, { "name": "protein SLFN14", "type": "synonym", "evidence": [ { "id": "NP_001192831", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001192831" } ] } ], "function": [], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Bos taurus", "taxid": 9913, "evidence": [ { "database": "UniProtKB", "id": "G3MZA6", "url": "https://www.uniprot.org/uniprotkb/G3MZA6" } ], "common_name": "Bovine", "glygen_name": "Bovine", "reference_species": "Bos taurus [9913]" } ], "gene": [ { "name": "SLFN14", "url": "https://www.uniprot.org/uniprotkb/G3MZA6", "locus": { "chromosome": "19", "start_pos": 14789087, "end_pos": 14778262, "strand": "-", "evidence": [ { "database": "Ensembl Gene", "id": "ENSBTAG00000039206", "url": "https://www.ensembl.org/id/ENSBTAG00000039206" } ] } } ], "crossref": [ { "id": "G3MZA6", "url": "https://alphafold.ebi.ac.uk/entry/G3MZA6", "database": "AlphaFoldDB", "categories": [] }, { "id": "ENSBTAG00000039206", "url": "https://bgee.org/?page=gene&gene_id=ENSBTAG00000039206", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "523379", "url": "https://www.ncbi.nlm.nih.gov/gene/523379", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR007421", "url": "https://www.ebi.ac.uk/interpro/entry/IPR007421", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR029684", "url": "https://www.ebi.ac.uk/interpro/entry/IPR029684", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR031450", "url": "https://www.ebi.ac.uk/interpro/entry/IPR031450", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR038461", "url": "https://www.ebi.ac.uk/interpro/entry/IPR038461", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR048729", "url": "https://www.ebi.ac.uk/interpro/entry/IPR048729", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "bta:523379", "url": "https://www.genome.jp/dbget-bin/www_bget?bta:523379", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "LHHGVLW", "url": "https://omabrowser.org/oma/group/LHHGVLW/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "G3MZA6", "url": "https://www.orthodb.org/?gene=G3MZA6", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR12155", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR12155", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR12155:SF30", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR12155:SF30", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF04326", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF04326", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF17057", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF17057", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF21026", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF21026", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "NP_001192831", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001192831", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "G3MZA6", "url": "https://www.uniprot.org/uniprotkb/G3MZA6", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "G3MZA6-1", "url": "https://www.uniprot.org/uniprotkb/G3MZA6-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MDSLKMETEMLYPEITVDVGRVTFGEENRKRMTNSYLKRTENSRIIQATCALLNSGGGVIKAEIEDKTYSYRCHGLGHDLETSFQKLFPSGSQKYLDYMQQGHNLMIFVKSWCPDIFSLRICSLRSNLYQRAVTSTINLSAHSALELLREKQSRTQRGRSTMQELHSQKALDRYMQEEEDMRMSASEFVKKDKLMYKEKLNFTESTHVEFKRFTTKKIIPRTKEMLPHYVSAFANTHGGYLIIGVDDKSKEVFGCQGEKVNPDLLKREIENCIEKLPTFHFCCEKPKVNFTTKILNVYQRDVLYGHVCVVHVEPFCCVVFTEAPDSWIIRDNSVTRLSAEQWVTMMLDIQSVPSNLEADHSLHLISSASSPLRSLSYPIKVLEFKEALQQHLFPVTPEKIQFKPESLCKKLFSDHKGLEELMKTQIYPCSQGFVIVSRSWASDVGLRKEQYVLCDALLIAVNSSPVLYTILTDSTWTGGLVYAQNTARQLKQKLGTVGGYTGKVCVIPRLVHLPGAQRKPSEITLRYPQPYRLADEDEMEKLLQALITVSLCSRSLLSDQLGCEFSNLLVAEQCELLSQSLQETRELFVHCFPGTRKTALAIKIMEKIKDLFHCKSKEILYVCESDALKDFVTQQTTCRAVTRKTFMGGEFPKVKHIVMDETEHFCSKYGDWYMKAKSITHPKVRGAGSGNPHHGILWLFLDPFQVHHGGGNGLPPPSAQFPRKTITNGIHCALEIAMLMKEEMKRLKENPHPSVSPDTLAAFREASYEEAMRAQALPGVCEIETNLTTEEIARHVAERCHHLFQCGYLPRDIAILCRRAEDRGRYELALLRAMELFETCGATKVVFSQASGVLDGHIVLDSIQQFSGLERNIVFGLSPEYALSEEVHKLCFASKAIKHLYLLYEKKATF", "length": 910, "header": "tr|G3MZA6-1|G3MZA6_BOVIN Isoform 1 of Schlafen family member 14 OS=Bos taurus OX=9913 GN=SLFN14 PE=4 SV=2 CANONICAL=G3MZA6-1" }, "isoforms": [ { "isoform_ac": "G3MZA6-1", "url": "https://www.uniprot.org/uniprotkb/G3MZA6/entry", "sequence": { "sequence": "MDSLKMETEMLYPEITVDVGRVTFGEENRKRMTNSYLKRTENSRIIQATCALLNSGGGVIKAEIEDKTYSYRCHGLGHDLETSFQKLFPSGSQKYLDYMQQGHNLMIFVKSWCPDIFSLRICSLRSNLYQRAVTSTINLSAHSALELLREKQSRTQRGRSTMQELHSQKALDRYMQEEEDMRMSASEFVKKDKLMYKEKLNFTESTHVEFKRFTTKKIIPRTKEMLPHYVSAFANTHGGYLIIGVDDKSKEVFGCQGEKVNPDLLKREIENCIEKLPTFHFCCEKPKVNFTTKILNVYQRDVLYGHVCVVHVEPFCCVVFTEAPDSWIIRDNSVTRLSAEQWVTMMLDIQSVPSNLEADHSLHLISSASSPLRSLSYPIKVLEFKEALQQHLFPVTPEKIQFKPESLCKKLFSDHKGLEELMKTQIYPCSQGFVIVSRSWASDVGLRKEQYVLCDALLIAVNSSPVLYTILTDSTWTGGLVYAQNTARQLKQKLGTVGGYTGKVCVIPRLVHLPGAQRKPSEITLRYPQPYRLADEDEMEKLLQALITVSLCSRSLLSDQLGCEFSNLLVAEQCELLSQSLQETRELFVHCFPGTRKTALAIKIMEKIKDLFHCKSKEILYVCESDALKDFVTQQTTCRAVTRKTFMGGEFPKVKHIVMDETEHFCSKYGDWYMKAKSITHPKVRGAGSGNPHHGILWLFLDPFQVHHGGGNGLPPPSAQFPRKTITNGIHCALEIAMLMKEEMKRLKENPHPSVSPDTLAAFREASYEEAMRAQALPGVCEIETNLTTEEIARHVAERCHHLFQCGYLPRDIAILCRRAEDRGRYELALLRAMELFETCGATKVVFSQASGVLDGHIVLDSIQQFSGLERNIVFGLSPEYALSEEVHKLCFASKAIKHLYLLYEKKATF", "length": 910, "header": "tr|G3MZA6-1|G3MZA6_BOVIN Isoform 1 of Schlafen family member 14 OS=Bos taurus OX=9913 GN=SLFN14 PE=4 SV=2 CANONICAL=G3MZA6-1" }, "locus": { "chromosome": "19", "start_pos": 14788890, "end_pos": 14780282, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000066055.3", "url": "https://www.ensembl.org/id/ENSBTAT00000066055.3" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000054902.2", "url": "https://www.ensembl.org/id/ENSBTAP00000054902.2" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [ { "id": "bta:523379", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?bta:523379", "resource": "KEGG Pathway" } ], "orthologs": [ { "uniprot_canonical_ac": "A0A096MK07-1", "protein_name": "Uncharacterized protein", "gene_name": "AC118772.1", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MPLAKDLLHPSPEEGKRKPKKKRLVQSPNSYFLDVKCTGCYKITTDFSHAQTVVLQISQGSRARNRGQTSHPEPDEELKHPEGTRAPVNSRDVFLLSLSVQKMPYAEITVNLGKVTLGEENRKEMTNSCLKRHENSSIVQAVCALLNSGGGVIKAKIDDKGYSYRCHGLGQDLETSFQKLLPSGSQKHLDYMQQDHDFLIFVKSWSPDASSLPLKICSLRSNIYQRDVTSAINLCASSALELLREKESRAQRGIPKLHSQDHILNRTIQEEEDIKMCALEFFKKDKLNYKEKLSFTESTHVEFKRFTTKKIVPRIKETLAHYVSAFANTQGGYIIIGVDDKSKEVFGCMKEKVNPDSLKTEIKNCIEKLPTYHFCREKPRVNFTTKILKVYQREALYGFVCVVQVEPFCCVVFAEDPDSWIMENNIVTRLKAQQWVEMMLAIQSDPSGFPTTADSAHPMSPALSAPGRPAYLTKVLEHKETLQRRFFPEKLFSDHEGLEDLLKTQTHPCSHGIVIFSRSWAGDIGLTREEKVLCDALLVAVGSPLVLYTVLTDPSWLGGSDYTQNTALQLKRRLQTLGGYRGKVCVIPRVICLPGRGSRPDPSPVYPRAYKLSSSAEVEDLLQSLVLVSLCSRSVLSDQLGCEFFKLCIEEEARALSRNLRETRELFIHCLPGTRKTALAIKMVEKIKDMFHCKPKEILYVCENDSLRDFVMQQVTCRAVTRRAFMREEFPKVKHIVLDETENFCSRHGDWYEKAKSTTHPKASGERLHHGILWLFLDPFQTRHPGASGLPAPSAQFPRKMITSEIHCAVEIAKVMKDEMKRIQENPPSNGSPDTLAMFQEVPYEEAMCAQALPGVCEIKANLTPGQIASYVAEKCHSLFHEGYRPQDIAILYRRWEDRGQYKEALLRAMARGTMEVSFNSAADICADGVIFDSVEQFSGMVRNIVFGLSTESVHSEGVHKLCFASRAVKHLYLLEAEIVLSPHQRGVVDGLSQRSTTVQNTGNKELEVPPPPDTAAIQPLNRRLHGKGVGQETLLWNTSRRPSNSGLCCRIIITVLLDKQTEDLGASRKQTTRLDLRTSCLPCRLPEISTQASPASCNPKRTQPLPVNRRMGENCSVLNRTVEGDKGTKGSRSEVWAVYDEETLALCRLSALKAWDKVAESEKKLEPFTQVIQGPKETFPDFLQRLTSAVERSVSDTAARKATVESLAFENVNTECREGIRPLRARSASVDEWIRQTADIGSSRLI", "length": 1247 }, "evidence": [ { "id": "G3MZA6", "url": "https://omabrowser.org/oma/group/G3MZA6/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "A0A8C2MHT8-1", "protein_name": "Protein SLFN14", "gene_name": "Slfn14", "tax_id": 10029, "organism": "Cricetulus griseus", "sequence": { "sequence": "MPYAEITIHLGKVTLGEKNRKKMTNGCLKRHENSSIIQAVCALLNSGGGVVKAEIVDENYSYQCHGLGQDLETSFQKLLPSGSQKYLDCMQQNHDLLIFVKSWSPDASSLPLKICSLRSNLYQRDVTSAINLSARSALELLKEKESRAQRGVPRVHSQECLLRRSIQEEEDIKVCASEFFKKDKLNYKEKLNFTESTHVEFKRFTTKKIVPRIKETLAHYISAFANTQGGYIIIGVDDESKEVFGCKKEKVNPESLKTEIRNCIEKLPTYHFCREKPKVDFTTKIMKVYQKEALYGYVCVVQVEPFCCLVFADDPDSWIMKDSNVKRLVAQQWVDMMLDIQPDPSSLPTTDYSAHPISPALPAPRRPAYLTKVLGYKGTLQRRLFPVTQASLQFQPESLCKKLFSDHNGLEGLLKAQIHPCSHGIVIVSRSWAGDIGLTKEQKVLCDALLVAVNSPLILYTILPDQSWNGGSNYTHNTALQLKQQLQTLGGYSGKVCVIPRQIYLTRRGPRPEQSLVCYPRSYTLSSKTEVEGVLQALVGVSVCSRSVLSDQLGCEFFKLRVEEQCNSLSQSLQETRELFIHCFPGTRKTALAIKITEKIKDVFHCKPKEILYVCGNDSLRDFVIQQVTCQIVTQRTFMREEFPKIKHIVMDETEDFCRRYDDWYMKAKSITHPKVKGAASENLHHGILWLFLDPFQTHHADVSGLPALSAQFPRKVITNEIHCAVEIANVMKEEMKRIQESPPPNISPDILAMFQEAPYEEAMCAQALPGVCEIKANLTLEQIANYVAEKCHSLFHEGYLPKDIAILYRREDRRQYKDVLLRTMVQRTTEVAFSSAADVCSDGIVLDSVQQFSGMVRNIVFGLSPECMQSEGAHKLCFASRAIKHLYLLYSRKTAS", "length": 897 }, "evidence": [ { "id": "G3MZA6", "url": "https://omabrowser.org/oma/group/G3MZA6/", "database": "OMA" } ], "glygen_name": "Hamster", "common_name": "Chinese hamster" }, { "uniprot_canonical_ac": "P0C7P3-1", "protein_name": "Protein SLFN14", "gene_name": "SLFN14", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MESLKTDTEMPYPEVIVDVGRVIFGEENRKKMTNSCLKRSENSRIIRAICALLNSGGGVIKAEIDDKTYSYQCHGLGQDLETSFQKLLPSGSQKYLDYMQQGHNLLIFVKSWSPDVFSLPLRICSLRSNLYRRDVTSAINLSASSALELLREKGFRAQRGRPRVKKLHPQQVLNRCIQEEEDMRILASEFFKKDKLMYKEKLNFTESTHVEFKRFTTKKVIPRIKEMLPHYVSAFANTQGGYVLIGVDDKSKEVVGCKWEKVNPDLLKKEIENCIEKLPTFHFCCEKPKVNFTTKILNVYQKDVLDGYVCVIQVEPFCCVVFAEAPDSWIMKDNSVTRLTAEQWVVMMLDTQSAPPSLVTDYNSCLISSASSARKSPGYPIKVHKFKEALQRHLFPVTQEEVQFKPESLCKKLFSDHKELEGLMKTLIHPCSQGIVIFSRSWAGDVGFRKEQNVLCDALLIAVNSPVVLYTILIDPNWPGGLEYARNTAHQLKQKLQTVGGYTGKVCIIPRLIHLSSTQSRPGEIPLRYPRSYRLADEEEMEDLLQALVVVSLSSRSLLSDQMGCEFFNLLIMEQSQLLSESLQKTRELFIYCFPGVRKTALAIKIMEKIKDLFHCKPKEILYVCESDSLKDFVTQQTTCQAVTRKTFMQGEFLKIKHIVMDETENFCSKYGNWYMKAKNITHPKAKGTGSENLHHGILWLFLDPFQIHHADVNGLPPPSAQFPRKTITSGIHCALEIAKVMKEEMKRIKENPPSNMSPDTLALFSETAYEEATCAQALPGVCETKTNLTTEQIANYVARKCHSLFQCGYLPKDIAILCRRGEDRGRYRLALLKAMELIETHRPSEVVFSPATGVWGSHIVLDSIQQFSGLERTVVFGLSPECDQSEEFHKLCFASRAIKHLYLLYEKRAAY", "length": 912 }, "evidence": [ { "id": "G3MZA6", "url": "https://omabrowser.org/oma/group/G3MZA6/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "V9GXG1-1", "protein_name": "Protein SLFN14", "gene_name": "Slfn14", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MPYAEITVNLGKVTLGEENRKKMTNSCLKRHENSSLVQAVCALLNSGGGVIKAEINDKSYSYRCHGLGQDLETSFQKLLPSGSQKHLDYMQQNHDLLIFVKSWSPDASSLPLRICSLRSNLYQRDVTSAINLCANGALELLREKESRAQRGTPRLHSQDHILNRTIQEEEDIKMCALEFLKKDKLNFKEKLSFTESTHVEFKRFTTKKIVPRIKETLAHYVSAFANTQGGYIIIGVDDKSKEVFGCKKEKVNPDSLKTEIKNCIEKLPTYHFCREKPKVNFTTKILKVYQKEALYGFVCVVQVEPFCCVVFAEDPDSWIMENNIVTRLKVQQWVEMMLDIQSDPSSGFPTINDSAHLMTPALSAPRRPAYLTKVLEHKETLQRHFFSVTQENLQFQPESLCKKLFSDHEGLEDLLKAQTHPCSHGIVIFSRSWAGDIGLMREEKVLCDALLVAVGSPLVLYTILTDPSSTGRADYTQNTALQLKRQLQTLGGYPGKICVIPRVIYLASRGSRPDQPPVYYPRPYTLSSKAEVEDLLQGLVLVSLCSRSVLSDQLGCEFFKQCLEEQANTLSRNLQESRELFIHCLPGTRKTALAIKMVEKIKDVFHCKPKEILFVCENDSLRDFVMQQVTCRAVTRRTFMREEFPKIKHIVMDETENFCSRHGDWYVKAKSTTHPKANGAANEHPHHGILWLFLDPFQVRHADGSGLPVPSAQFPRKMITSEIHCAVEIAKVMKDEMKRMQENPPSMGLPDTLATFQEAPYEEAMRAGALPGVCEIKANLTPEQIANYVAEKCHSLFHEGYLPQDIAILYRRREDRGQYKDVLLKAMARGTTEVAFNSAADVCADGIILDSVEQFSGMVRNIVFGLCPESVHSEGVHKLCFASKAIKHLYLLYGGRTAF", "length": 899 }, "evidence": [ { "id": "G3MZA6", "url": "https://omabrowser.org/oma/group/G3MZA6/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" } ], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 2, "go_terms": [ { "name": "nucleus", "id": "GO:0005634", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005634", "evidence": [ { "database": "UniProtKB", "id": "G3MZA6", "url": "https://www.uniprot.org/uniprotkb/G3MZA6" } ], "pmid": "" }, { "name": "cytoplasm", "id": "GO:0005737", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005737", "evidence": [ { "database": "UniProtKB", "id": "G3MZA6", "url": "https://www.uniprot.org/uniprotkb/G3MZA6" } ], "pmid": "" } ] }, { "name": "Molecular Function", "total": 2, "go_terms": [ { "name": "ribosome binding", "id": "GO:0043022", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0043022", "evidence": [ { "database": "UniProtKB", "id": "G3MZA6", "url": "https://www.uniprot.org/uniprotkb/G3MZA6" } ], "pmid": "" }, { "name": "RNA endonuclease activity", "id": "GO:0004521", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0004521", "evidence": [ { "database": "UniProtKB", "id": "G3MZA6", "url": "https://www.uniprot.org/uniprotkb/G3MZA6" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 3, "go_terms": [ { "name": "mRNA catabolic process", "id": "GO:0006402", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006402", "evidence": [ { "database": "UniProtKB", "id": "G3MZA6", "url": "https://www.uniprot.org/uniprotkb/G3MZA6" } ], "pmid": "" }, { "name": "rRNA catabolic process", "id": "GO:0016075", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016075", "evidence": [ { "database": "UniProtKB", "id": "G3MZA6", "url": "https://www.uniprot.org/uniprotkb/G3MZA6" } ], "pmid": "" }, { "name": "platelet maturation", "id": "GO:0036345", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0036345", "evidence": [ { "database": "UniProtKB", "id": "G3MZA6", "url": "https://www.uniprot.org/uniprotkb/G3MZA6" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 138, "end_pos": 140, "annotation": "n_glycosylation_sequon" }, { "start_pos": 201, "end_pos": 203, "annotation": "n_glycosylation_sequon" }, { "start_pos": 289, "end_pos": 291, "annotation": "n_glycosylation_sequon" }, { "start_pos": 462, "end_pos": 464, "annotation": "n_glycosylation_sequon" }, { "start_pos": 786, "end_pos": 788, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [ { "pdb_id": "AF-G3MZA6-F1", "pdb_chain": "global", "start_pos": 1, "end_pos": 910, "overlap": "1.0", "method": "AlphaFold", "type": "alphafold", "resolution": -1.0, "url": "https://data.glygen.org/ln2downloads/pdb/current/AF-G3MZA6-F1.pdb", "url_external": "https://alphafold.ebi.ac.uk/entry/G3MZA6" } ], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "G3MZA6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3MZA6" }, { "id": "PF17057", "database": "Pfam", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF17057" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "Poxin-Schlafen/Schlafen-like N-terminal", "eco_id": "ECO_0000259", "start_pos": 85, "end_pos": 202, "start_aa": "Gln", "end_aa": "Phe", "glycosite_overlap": [] }, { "evidence": [ { "id": "G3MZA6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3MZA6" }, { "id": "PF04326", "database": "Pfam", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF04326" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "Schlafen AlbA-2", "eco_id": "ECO_0000259", "start_pos": 204, "end_pos": 334, "start_aa": "Glu", "end_aa": "Val", "glycosite_overlap": [] }, { "evidence": [ { "id": "G3MZA6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3MZA6" }, { "id": "PF21026", "database": "Pfam", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF21026" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "Schlafen GTPase-like", "eco_id": "ECO_0000259", "start_pos": 398, "end_pos": 533, "start_aa": "Glu", "end_aa": "Leu", "glycosite_overlap": [] } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "homologset.oma", "label": "OMA Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 138, "end_pos": 140 }, { "start_pos": 201, "end_pos": 203 }, { "start_pos": 289, "end_pos": 291 }, { "start_pos": 462, "end_pos": 464 }, { "start_pos": 786, "end_pos": 788 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ], "tool_support": { "graph_view": "yes" } }, { "uniprot_canonical_ac": "G3MZB5-1", "uniprot_ac": "G3MZB5", "uniprot_id": "G3MZB5_BOVIN", 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"http://www.pantherdb.org/panther/family.do?clsAccession=PTHR24388", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR24388:SF51", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR24388:SF51", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00096", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00096", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF13912", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF13912", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "XP_002689155", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_002689155", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "G3MZJ3", "url": "https://www.uniprot.org/uniprotkb/G3MZJ3", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "G3MZJ3-1", "url": "https://www.uniprot.org/uniprotkb/G3MZJ3-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MFAASEVAAGRPYGCSECGKSFRYSSVLLRHERVHSRDSSFRCLECGERCAEASDLRAHRRAHAGQTLYICSECGQSFRHSGRLDLHQSVHRRRIRSCRCRACGGCFPHLPALLLHRRRWHPPERPHRCPLCPRAFRQSALRFHLARAHPWGTPTVPADTLHRCTQCSRAFRSVAGLRSHLRVHAARSPSDSTLRQPGAPDTHQCGVCGKSFGKSSTLTRHLQTHSGEKPFKCPECGKGFLESATLVRHQRTHTGEKPYACSDCGRRFSESSTLLRHRRSHQGERPHACATCGKGFGQRSDLVVHQRIHTGERPFPCTECGRCFSDRSDLTKHRRTHTGEKPYRCELCGKCFTCISNLNVHRRNHAGHKPHKCPECGKAFSVGSKLALHRKTHLGERPAECAECGKCFSHSRSLSQHQRAHRRARASTAPAAAATQPKAGTALIVAGQAGQEKPGLFLSQLRETC", "length": 465, "header": "tr|G3MZJ3-1|G3MZJ3_BOVIN Isoform 1 of Zinc finger protein 672 OS=Bos taurus OX=9913 GN=ZNF672 PE=3 SV=1 CANONICAL=G3MZJ3-1" }, "isoforms": [ { "isoform_ac": "G3MZJ3-1", "url": "https://www.uniprot.org/uniprotkb/G3MZJ3/entry", "sequence": { "sequence": "MFAASEVAAGRPYGCSECGKSFRYSSVLLRHERVHSRDSSFRCLECGERCAEASDLRAHRRAHAGQTLYICSECGQSFRHSGRLDLHQSVHRRRIRSCRCRACGGCFPHLPALLLHRRRWHPPERPHRCPLCPRAFRQSALRFHLARAHPWGTPTVPADTLHRCTQCSRAFRSVAGLRSHLRVHAARSPSDSTLRQPGAPDTHQCGVCGKSFGKSSTLTRHLQTHSGEKPFKCPECGKGFLESATLVRHQRTHTGEKPYACSDCGRRFSESSTLLRHRRSHQGERPHACATCGKGFGQRSDLVVHQRIHTGERPFPCTECGRCFSDRSDLTKHRRTHTGEKPYRCELCGKCFTCISNLNVHRRNHAGHKPHKCPECGKAFSVGSKLALHRKTHLGERPAECAECGKCFSHSRSLSQHQRAHRRARASTAPAAAATQPKAGTALIVAGQAGQEKPGLFLSQLRETC", "length": 465, "header": "tr|G3MZJ3-1|G3MZJ3_BOVIN Isoform 1 of Zinc finger protein 672 OS=Bos taurus OX=9913 GN=ZNF672 PE=3 SV=1 CANONICAL=G3MZJ3-1" }, "locus": { "chromosome": "7", "start_pos": 42629255, "end_pos": 42627861, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000135715.1", "url": "https://www.ensembl.org/id/ENSBTAT00000135715.1" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000098391.1", "url": "https://www.ensembl.org/id/ENSBTAP00000098391.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [ { "id": "bta:539058", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?bta:539058", "resource": "KEGG Pathway" } ], "orthologs": [ { "uniprot_canonical_ac": "F1S5U0-1", "protein_name": "Zinc finger protein 672", "gene_name": "ZNF672", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MFAASEAGVGRPYTCSECGKSFRYSSVLLRHERAHGSDSHLRCLECGEHCAQAADLRSHRRVHAGQTLYICSECGQSFRHSGRLDLHQSVHRRRGRSCRCRTCGRCFPHLPALLLHRRHWHPPERPCRCPLCPRAFRQSALRFHQARAHPWGIPAVPTDTLHHCTQCSRVFCSGVGLRRHLRVHVARSPGDSTLQQPATLDAHQCGVCGKSFAKSSTLTRHLQAHSGEKPFKCPECGKGFLESATLVRHQRTHTGEKPYACGDCGRRFSESSTLLRHRRSHQGERPHACATCGKGFGQRSDLIVHQRIHTGERPFPCTECGRCFSDRSDLTKHWRTHTGEKPYRCELCGKRFTCVSNLNVHLRNHAGHKPHKCPECGKAFSVSSKLALHRKTHLGERPAECAECGKCFSHSRSLSQHQRAHTRARAATTAATATQDKASTALIFAEQARQEKLGFSVPKFKETC", "length": 464 }, "evidence": [ { "id": "G3MZJ3", "url": "https://omabrowser.org/oma/group/G3MZJ3/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "Q499Z4-1", "protein_name": "Zinc finger protein 672", "gene_name": "ZNF672", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MFATSGAVAAGKPYSCSECGKSFCYSSVLLRHERAHGGDGRFRCLECGERCARAADLRAHRRTHAGQTLYICSECGQSFRHSGRLDLHLGAHRQRCRTCPCRTCGRRFPHLPALLLHRRRQHLPERPRRCPLCARTFRQSALLFHQARAHPLGTTSDPAAPPHRCAQCPRAFRSGAGLRSHARIHVSRSPTRPRVSDAHQCGVCGKCFGKSSTLTRHLQTHSGEKPFKCPECGKGFLESATLVRHQRTHTGEKPYACGDCGRCFSESSTLLRHRRSHQGERPHACATCGKGFGQRSDLVVHQRIHTGEKPFACPECGRRFSDRSDLTKHRRTHTGEKPYRCELCGKRFTCVSNLNVHRRNHAGHKPHKCPECSKAFSVASKLALHRKTHLGERPAECAECGKCFSHSRSLSQHQRAHTRARTAAAVAIQSAVGTALVFEGPAEQEKPGFSVS", "length": 452 }, "evidence": [ { "id": "G3MZJ3", "url": "https://omabrowser.org/oma/group/G3MZJ3/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "Q642B2-1", "protein_name": "Zinc finger protein 672", "gene_name": "Znf672", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MFTAPGVAATRERPYSCSVCGKSFQYSAVLLRHERAHGGDKRFRCLECGERCARASDLRVHRWTHAGQTLYICSECGQSFSHSSLLDLHLGTHRRRSSTCPCRLCGRRFPHVSALLLHRVRQHPPEKPHRCPLCARSFRQSALPFHLARAHPPETTIATAPAPSTLYHCTQCPRAFHSSAGLRNHSRIHVVPSLSDPGAEAHRCGVCGKSFSKSSTLTRHLQRHSGEKPFKCPECGKGFLESATLVRHQRTHTGEKPYACNDCGRCFSESSTLLRHQRSHQGERPHICATCGKGFGQRYDLVVHQRSHTGERPFPCPECGRGFTDRSDLTKHLRTHTGEKPYHCELCGKRFTCISNLNVHLRNHAGHKPHKCPECGKSFSVASKLALHRKTHLGERTAECTECGKFFSHGRSLSQHQRSHRRARAAAMAATTTTTVVTEMTIGPSLTLTGPTEQEKSGLLVSTFQETC", "length": 468 }, "evidence": [ { "id": "G3MZJ3", "url": "https://omabrowser.org/oma/group/G3MZJ3/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "Q99LH4-1", "protein_name": "Zinc finger protein 672", "gene_name": "Znf672", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MFTAPGMATTQERPYSCSVCGKSFQYSAVLLRHERAHGGDKRFCCLECGERCARAADLRAHRWTHAGQTLYICSECGQSFSHSGLLDLHLGTHRRRSRTRPCRLCGRRFPHVPALLLHRARQHPPEKPHRCPLCARSFRQSALPFHLARAHPPEIITVTAPSPSTLYHCTQCPRAFHSSAGLRNHSRIHVVPSLSDPGTEAHLCGICGKSFSKSSTLTRHLQRHSGEKPFKCPECGKGFLESATLVRHQRTHTGEKPYACSDCGRCFSESSTLLRHQRSHQGERPHVCATCGKGFGQRYDLVVHQRSHTGERPFPCPQCGRGFTDRSDLTKHLRTHTGEKPYHCELCGKRFTCISNLNVHLRNHAGHKPHKCPECGKSFSVASKLALHRKTHLGERTAECTECGKFFSHGRSLSQHQRSHRRARAAAMAATTTTTVVTEVTIGPSLTLTGPTEQEKSGLLVSPFQETC", "length": 468 }, "evidence": [ { "id": "G3MZJ3", "url": "https://omabrowser.org/oma/group/G3MZJ3/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" } ], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 1, "go_terms": [ { "name": "nucleus", "id": "GO:0005634", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005634", "evidence": [ { "database": "UniProtKB", "id": "G3MZJ3", "url": "https://www.uniprot.org/uniprotkb/G3MZJ3" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 2, "go_terms": [ { "name": "DNA-templated transcription", "id": "GO:0006351", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006351", "evidence": [ { "database": "UniProtKB", "id": "G3MZJ3", "url": "https://www.uniprot.org/uniprotkb/G3MZJ3" } ], "pmid": "" }, { "name": "regulation of transcription by RNA polymerase II", "id": "GO:0006357", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006357", "evidence": [ { "database": "UniProtKB", "id": "G3MZJ3", "url": "https://www.uniprot.org/uniprotkb/G3MZJ3" } ], "pmid": "" } ] }, { "name": "Molecular Function", "total": 2, "go_terms": [ { "name": "zinc ion binding", "id": "GO:0008270", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008270", "evidence": [ { "database": "UniProtKB", "id": "G3MZJ3", "url": "https://www.uniprot.org/uniprotkb/G3MZJ3" } ], "pmid": "" }, { "name": "transcription cis-regulatory region binding", "id": "GO:0000976", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000976", "evidence": [ { "database": "UniProtKB", "id": "G3MZJ3", "url": "https://www.uniprot.org/uniprotkb/G3MZJ3" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "G3MZJ3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3MZJ3" }, { "id": "PS50157", "database": "PROSITE", "url": "https://prosite.expasy.org/PS50157" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "C2H2-type", "eco_id": "ECO_0000259", "start_pos": 13, "end_pos": 40, "start_aa": "Tyr", "end_aa": "Ser", "glycosite_overlap": [] } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "homologset.oma", "label": "OMA Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": 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The olfactory receptor proteins are members of a large family of G-protein-coupled receptors (GPCR) arising from single coding-exon genes. Olfactory receptors share a 7-transmembrane domain structure with many neurotransmitter and hormone receptors and are responsible for the recognition and G protein-mediated transduction of odorant signals. The olfactory receptor gene family is the largest in the genome. [provided by RefSeq, Jul 2008].", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001377530" }, "gene_names": [ { "name": "OR51S1B", "type": "recommended", "evidence": [ { "id": "G3MZJ6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3MZJ6" } ] }, { "name": "OR51S1B", "type": "synonym", "evidence": [ { "id": "NP_001377530", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001377530" } ] } ], "protein_names": [ { "name": "Olfactory receptor family 51 subfamily S member 1B", "type": "synonym", "evidence": [ { "id": "G3MZJ6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3MZJ6/entry#names_and_taxonomy" } ] }, { "name": "olfactory receptor 51S1", "type": "synonym", "evidence": [ { "id": "NP_001377530", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001377530" } ] }, { "name": "olfactory receptor family 51 subfamily S member 1B", "type": "synonym", "evidence": [ { "id": "NP_001377530", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001377530" } ] } ], "function": [ { "annotation": "Olfactory receptors interact with odorant molecules in the nose, to initiate a neuronal response that triggers the perception of a smell. The olfactory receptor proteins are members of a large family of G-protein-coupled receptors (GPCR) arising from single coding-exon genes. Olfactory receptors share a 7-transmembrane domain structure with many neurotransmitter and hormone receptors and are responsible for the recognition and G protein-mediated transduction of odorant signals. The olfactory receptor gene family is the largest in the genome. 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"url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR31815", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR31815:SF2", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR31815:SF2", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF10177", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF10177", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "NP_001193588", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001193588", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "G3MZJ8", "url": "https://www.uniprot.org/uniprotkb/G3MZJ8", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "G3MZJ8-1", "url": "https://www.uniprot.org/uniprotkb/G3MZJ8-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MIATGGLLRISARKQDPLRPPGQVPKRKRKTKKRRKNDVVVVKGKLKLCSVSGLIALCGIVVLLVGIALAVVGYWPKANGAHREGAKQPPPPPGDSGPRVPSVTSSSGGNRNRSRTQPGPPEGVTASSVGAPRSTPPARSPAPSPSSSTSVGFFFRVFSGYLHSDKLKVFGPLIMGIGIFLFICANAVLHENRDKETKIINLRDLYSTVIDVHSLRAKDLAAAASSSGPASAPPGAAPLNGFLGYVQSRGLELKPGTRGGAARDAFGAAAMLARGAWPHPAARSGGGGGTPGAASPPDLVSSPRRPREPPSLAEAVYSIYRERPGVAGRRRAASSGSSPVPGSPPETWGRPSTASSLVGSSLSAFALLPLPGDRDGDAGAASRGWQRPPGERGAREIPLDLSLADLRGGARGGARWAPREPEEPAAARTARGQGGRLPRTGRHAALRRRSTSGLPDYRAASYPEPPSASRSADLDSSLPELAASPESPARPDSPSSHSDDPSCSNKGYTPLRETGTSLESMGDLREGGNPDGEAAIAPGPEQRPPEDPGQEVPEAEPSQPVQRQFTNKEKLYMISRSHASGVEDGELESAGI", "length": 592, "header": "tr|G3MZJ8-1|G3MZJ8_BOVIN Isoform 1 of Transmembrane protein 200C OS=Bos taurus OX=9913 GN=TMEM200C PE=3 SV=2 CANONICAL=G3MZJ8-1" }, "isoforms": [ { "isoform_ac": "G3MZJ8-1", "url": "https://www.uniprot.org/uniprotkb/G3MZJ8/entry", "sequence": { "sequence": "MIATGGLLRISARKQDPLRPPGQVPKRKRKTKKRRKNDVVVVKGKLKLCSVSGLIALCGIVVLLVGIALAVVGYWPKANGAHREGAKQPPPPPGDSGPRVPSVTSSSGGNRNRSRTQPGPPEGVTASSVGAPRSTPPARSPAPSPSSSTSVGFFFRVFSGYLHSDKLKVFGPLIMGIGIFLFICANAVLHENRDKETKIINLRDLYSTVIDVHSLRAKDLAAAASSSGPASAPPGAAPLNGFLGYVQSRGLELKPGTRGGAARDAFGAAAMLARGAWPHPAARSGGGGGTPGAASPPDLVSSPRRPREPPSLAEAVYSIYRERPGVAGRRRAASSGSSPVPGSPPETWGRPSTASSLVGSSLSAFALLPLPGDRDGDAGAASRGWQRPPGERGAREIPLDLSLADLRGGARGGARWAPREPEEPAAARTARGQGGRLPRTGRHAALRRRSTSGLPDYRAASYPEPPSASRSADLDSSLPELAASPESPARPDSPSSHSDDPSCSNKGYTPLRETGTSLESMGDLREGGNPDGEAAIAPGPEQRPPEDPGQEVPEAEPSQPVQRQFTNKEKLYMISRSHASGVEDGELESAGI", "length": 592, "header": "tr|G3MZJ8-1|G3MZJ8_BOVIN Isoform 1 of Transmembrane protein 200C OS=Bos taurus OX=9913 GN=TMEM200C PE=3 SV=2 CANONICAL=G3MZJ8-1" }, "locus": { "chromosome": "24", "start_pos": 39308899, "end_pos": 39307124, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000064830.3", "url": "https://www.ensembl.org/id/ENSBTAT00000064830.3" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000054997.2", "url": "https://www.ensembl.org/id/ENSBTAP00000054997.2" } ] } } ], "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "other", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 290, "start_aa": "Thr", "end_pos": 290, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr290", "evidence": [ { "id": "", "database": "GlyGen", "url": "https://data.glygen.org/" } ], "filter_code": "000000000000000010000.00000000001000.0.01000" } ], "phosphorylation": [], "glycation": [], "keywords": [ "glycoprotein", "glycoprotein_predicted" ], "publication": [], "pathway": [ { "id": "bta:786855", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?bta:786855", "resource": "KEGG Pathway" } ], "orthologs": [ { "uniprot_canonical_ac": "A0A8V0X732-1", "protein_name": "Transmembrane protein 200C", "gene_name": "TMEM200C", "tax_id": 9031, "organism": "Gallus gallus", "sequence": { "sequence": "MIATGGLLRISARKQDPLRPQSQIPKRKRKAKKKRKNDVVVVKGKLKLCSISGLIALCGILVLLVGIALAVVGYWPKPSQVYREVGGGRHLAPQGGTPKNRSQNQEGAQAEIYPVSSPRANSTAATSQEFPQSPPTSSSPQASVGFLFRLFSSYLHSDKLKVLGPLIMGIGIFLFICANAVLHENRDKKTKIINLRDLYSTVIDAHSLRAKDGGASAPLNGFVNYVQSRGLELKPGGEGLGAAAMLAKSSWPPGLAASFSPPDLASSPRRSSCTLPQPPSLAEAVYSIYRDRAAHTGRTFTSPPCSPPESWGQRSTASSIVGSSLSAFTLLPLAQSGRGGGWRRPPGERGAQEIPRGEFELSLTDLSHVEGGYRTRRHKVVLRRQSTSCLPDARRPLSPEPPQSPVVRGGPDSSLLASSSHSRSLDLGESPPSTSPAITRTDSQSSQSEHSSSNKGYSHLEEAGTSLESVANTPASKIQDREEEPVEKMDPLKATSTEQTGEQSQQTQRQYTNKEKLFMISRSHAALGLEDGELESTGI", "length": 539 }, "evidence": [ { "id": "G3MZJ8", "url": "https://omabrowser.org/oma/group/G3MZJ8/", "database": "OMA" } ], "glygen_name": "Chicken", "common_name": "Chicken" }, { "uniprot_canonical_ac": "A6NKL6-1", "protein_name": "Transmembrane protein 200C", "gene_name": "TMEM200C", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MIATGGLLRISARKQDPLRPPSQIPKRKRKAKKRRKNDVVVVKGKLKLCSISGLIALCGILVLLVGIAMAVVGYWPKATGTNREGGKQLPPAGSSHRVPTTANSSSSGSKNRSRSHPRAPGGVNSSSAGAPRSTPPARAASPSSSSTSVGFFFRIFSGYLHSDKLKVFGPLIMGIGIFLFICANAVLHENRDKKTKIINLRDLYSTVIDVHSLRAKDLAAAAAAAAAAAASSSSSAPAAAPPGAIPLNGFLSYVQSRGLELKPGGCGGSGDAFGAAAMLAKGSWPPHPAAPSGGRPRGAASPPDLASSPRCPREPPSLAEAVYSVYRERSGVAGSRRAAAATAAAAASSCSSPAPCSPPESWGRQSTASSFVDSSLSAFALLPLQGGRDRGGDAEGASCSWQRPPGERGSQEIPRGELDLSMTNLRGAEGSMRGARREPEEPEGAVAARAARGQGGRLPRTGRYAALRRRSTSGLPDYRAPPSPEPPPSPGSADPDSSPLAKAASPSPPLRLEGSPPTRRDSGSSQSDDPSSSNKGYTPLREAGTSTESVLDAVAGQTRDSAVAAPVLGAEQSSPEGASQEPPTAEQPQPVQRQFTNKEKLIMISRSHAIGVEEELESTGI", "length": 621 }, "evidence": [ { "id": "G3MZJ8", "url": "https://omabrowser.org/oma/group/G3MZJ8/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "J3QK46-1", "protein_name": "Transmembrane protein 200C", "gene_name": "Tmem200c", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MIATGGLLRISARKQDPLRPPSQVPKRKRKAKKRRKNDVVVVKGKLKLCSISGLIALCGILVLLVGIAMAVVGYWPKANAANRGGSKQLLPVGSSHRIGAISNSSNGNKNPAKSHSGTPGGANSSSVGGPWSPPPARSAATSSSSSSSSSSSSSTSVGFFFRIFSGYLHSDKLKVFGPLIMGIGIFLFICANAVLHENRDKKTKIINLRDLYSTVIDVHSLRAKDLAAAAAAAAAAAASSSAAAPGSASHGAAPLNGFLSYVQSRGLELKPGSCAGSADAFGAAAMLARGSWPHPTGLDGGSGETQEAGSPPDLASSPRCPREPPSLTEAVYSIYRERSSRAGHRRTTVAAVAAATATVTAAASGGSSPAPCSPTGSWGRQSTTSSLVGSSLSAFALLPLQGDRDRDGDSEGASCSWHRPPGERGSRDLPRGELDLSLTDLRGAEGGARWASCEPGEPEGAKTARTARGQGGRLPRTRRYAAWRRRSTSGLPDYRAPPSPEPPPSSSAENLDSGPSATAATPSLPLRPEEDSPRVRRDSHSSQSDDQSSSNKGYTPLREADTSVESVVDVVAKKRLDCEDVTDPSTEHSSPEGPSPGPTRAEPLSVQRQFTNKEKLFLISRSHTPGVEDPELKKSSN", "length": 637 }, "evidence": [ { "id": "G3MZJ8", "url": "https://omabrowser.org/oma/group/G3MZJ8/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "M0R5E3-1", "protein_name": "Transmembrane protein 200C", "gene_name": "Tmem200c", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MIATGGLLRISARKQDPLRPPSQVPKRKRKAKKRRKNDVVVVKGKLKLCSISGLIALCGILVLLVGIAMAVVGYWPKANAANRGGSKQFLPVGSIHRTGAASNSSSGNKNPAKNHSGTPGGVNSSSVGGPRSSPPARTAATSSSSSSSSSSSSTSVGFFFRIFSGYLHSDKLKVFGPLIMGIGIFLFICANAVLHENRDKKTKIINLRDLYSTVIDVHSLRAKDLAAAAAAAAAAAASSSAAAPGSAPPGAAPLNGFLNYVQSRGLELKPGSCAGSADAFGAAAMLARGSWPHPAGLGGGGSGTREAGSPPDLASSPRCPREPPSLTEAVYSIYRERSSGAGRRRTTVAAVAAATATVTAAASGGSSPAPCSPTGSWGRQSTASSLVGSSLSAFALLPLHGDRDRDRDSEGASCSWHRPPGERGSRDLPRGELDLSLTDLRGAEGGARWASGEPEEPEGGTTACTARGQGRRLPRTGRYAAWRRRSTSGLPEYRAPPSPEPPPSGFAADLDSGPPGTVATPSLPLRPEDSPGVRRDSHSSQSDDQSSSNKGYTPLREADTSVESVVDVVARKRLDCEAATDPSTEHSSPEGPSPEPTRVELHTGQRQFTNKEKLFLISRSHTPGVEDPELENSSN", "length": 635 }, "evidence": [ { "id": "G3MZJ8", "url": "https://omabrowser.org/oma/group/G3MZJ8/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" } ], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 1, "go_terms": [ { "name": "membrane", "id": "GO:0016020", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016020", "evidence": [ { "database": "UniProtKB", "id": "G3MZJ8", "url": "https://www.uniprot.org/uniprotkb/G3MZJ8" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 112, "end_pos": 114, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [ { "pdb_id": "AF-G3MZJ8-F1", "pdb_chain": "global", "start_pos": 1, "end_pos": 592, "overlap": "1.0", "method": "AlphaFold", "type": "alphafold", "resolution": -1.0, "url": "https://data.glygen.org/ln2downloads/pdb/current/AF-G3MZJ8-F1.pdb", "url_external": "https://alphafold.ebi.ac.uk/entry/G3MZJ8" } ], "lectin_list": [], "domain_list": [], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "homologset.oma", "label": "OMA Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [ 290 ], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 112, "end_pos": 114 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 1 }, { "field": "total_sites", "count": 1 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 1 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "exact_sites", "count": 1 }, { "field": "exact_o_linked_sites", "count": 1 }, { "field": "fuzzy_sites", "count": 0 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_pos", "start_aa", "end_pos", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 1 }, { "field": "total_sites", "count": 1 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 1 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "exact_sites", "count": 1 }, { "field": "exact_o_linked_sites", "count": 1 }, { "field": "fuzzy_sites", "count": 0 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_pos", "start_aa", "end_pos", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ], "tool_support": { "graph_view": "yes" } }, { "uniprot_canonical_ac": "G3MZK0-1", "uniprot_ac": "G3MZK0", "uniprot_id": "G3MZK0_BOVIN", "mass": { "chemical_mass": 29693.0, "monoisotopic_mass": 29693.0 }, "refseq": { "ac": "XP_002698897", "name": "2-aminoethanethiol dioxygenase", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_002698897" }, "gene_names": [ { "name": "ADO", "type": "recommended", "evidence": [ { "id": "G3MZK0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3MZK0" } ] }, { "name": "ADO", "type": "synonym", "evidence": [ { "id": "XP_002698897", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_002698897" } ] } ], "protein_names": [ { "name": "2-aminoethanethiol dioxygenase", "type": "recommended", "evidence": [ { "id": "G3MZK0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3MZK0/entry#names_and_taxonomy" } ] }, { "name": "1.13.11.19", "type": "synonym", "evidence": [ { "id": "G3MZK0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3MZK0/entry#names_and_taxonomy" } ] }, { "name": "2-aminoethanethiol dioxygenase", "type": "synonym", "evidence": [ { "id": "XP_002698897", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_002698897" } ] }, { "name": "Cysteamine dioxygenase", "type": "synonym", "evidence": [ { "id": "G3MZK0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3MZK0/entry#names_and_taxonomy" } ] } ], "function": [], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Bos taurus", "taxid": 9913, "evidence": [ { "database": "UniProtKB", "id": "G3MZK0", "url": "https://www.uniprot.org/uniprotkb/G3MZK0" } ], "common_name": "Bovine", "glygen_name": "Bovine", "reference_species": "Bos taurus [9913]" } ], "gene": [ { "name": "ADO", "url": "https://www.uniprot.org/uniprotkb/G3MZK0", "locus": { "chromosome": "28", "start_pos": 18930094, "end_pos": 18928643, "strand": "-", "evidence": [ { "database": "Ensembl Gene", "id": "ENSBTAG00000045717", "url": "https://www.ensembl.org/id/ENSBTAG00000045717" } ] } } ], "crossref": [ { "id": "G3MZK0", "url": "https://alphafold.ebi.ac.uk/entry/G3MZK0", "database": "AlphaFoldDB", "categories": [] }, { "id": "ENSBTAG00000045717", "url": "https://bgee.org/?page=gene&gene_id=ENSBTAG00000045717", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "cd20289", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd20289", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "100297937", "url": "https://www.ncbi.nlm.nih.gov/gene/100297937", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR011051", "url": "https://www.ebi.ac.uk/interpro/entry/IPR011051", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR012864", "url": "https://www.ebi.ac.uk/interpro/entry/IPR012864", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR014710", "url": "https://www.ebi.ac.uk/interpro/entry/IPR014710", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "bta:100297937", "url": "https://www.genome.jp/dbget-bin/www_bget?bta:100297937", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "PTHR22966", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR22966", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR22966:SF61", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR22966:SF61", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF07847", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF07847", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "R-BTA-1614558", "url": "https://www.reactome.org/PathwayBrowser/#R-BTA-1614558", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "XP_002698897", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_002698897", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "14409", "url": "https://www.rhea-db.org/rhea/14409", "database": "Rhea", "categories": [ "Enzyme and Pathway" ] }, { "id": "70895", "url": "https://www.rhea-db.org/rhea/70895", "database": "Rhea", "categories": [ "Enzyme and Pathway" ] }, { "id": "G3MZK0", "url": "https://www.uniprot.org/uniprotkb/G3MZK0", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "G3MZK0-1", "url": "https://www.uniprot.org/uniprotkb/G3MZK0-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MPRDNMASLIQRIARQACLTFRGSGGGRSSSDRGEAPGPEAPIPQGFPENLSKLKSLLTQVRAEDLNISPRKATVQPLRPNLPPVTYMHICETDGFSLGVFLLKSGTSIPLHDHPGMHGILKVLYGTVRISCMDKLEVGSGQRPRAPPPEQQFEPPLQPRELDAVQPGVLRSRAEYTEASGPCFLTPHRDNLHQIDAVDGPAAFLDILAPPYDPDDGRDCHYYRVLEPVRAKEASGSACDLPREVWLLETPQADDFWCEGEPYPGPKVFP", "length": 270, "header": "tr|G3MZK0-1|G3MZK0_BOVIN Isoform 1 of 2-aminoethanethiol dioxygenase OS=Bos taurus OX=9913 GN=ADO PE=4 SV=3 CANONICAL=G3MZK0-1" }, "isoforms": [ { "isoform_ac": "G3MZK0-1", "url": "https://www.uniprot.org/uniprotkb/G3MZK0/entry", "sequence": { "sequence": "MPRDNMASLIQRIARQACLTFRGSGGGRSSSDRGEAPGPEAPIPQGFPENLSKLKSLLTQVRAEDLNISPRKATVQPLRPNLPPVTYMHICETDGFSLGVFLLKSGTSIPLHDHPGMHGILKVLYGTVRISCMDKLEVGSGQRPRAPPPEQQFEPPLQPRELDAVQPGVLRSRAEYTEASGPCFLTPHRDNLHQIDAVDGPAAFLDILAPPYDPDDGRDCHYYRVLEPVRAKEASGSACDLPREVWLLETPQADDFWCEGEPYPGPKVFP", "length": 270, "header": "tr|G3MZK0-1|G3MZK0_BOVIN Isoform 1 of 2-aminoethanethiol dioxygenase OS=Bos taurus OX=9913 GN=ADO PE=4 SV=3 CANONICAL=G3MZK0-1" }, "locus": { "chromosome": "28", "start_pos": 18929823, "end_pos": 18929014, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000064438.3", "url": "https://www.ensembl.org/id/ENSBTAT00000064438.3" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000054999.3", "url": "https://www.ensembl.org/id/ENSBTAP00000054999.3" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [ "enzyme" ], "publication": [], "pathway": [ { "id": "bta:100297937", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?bta:100297937", "resource": "KEGG Pathway" }, { "id": "R-BTA-1614558", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-BTA-1614558", "resource": "Reactome", "description": "Degradation of cysteine and homocysteine" } ], "orthologs": [], "go_annotation": { "categories": [ { "name": "Molecular Function", "total": 2, "go_terms": [ { "name": "iron ion binding", "id": "GO:0005506", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005506", "evidence": [ { "database": "UniProtKB", "id": "G3MZK0", "url": "https://www.uniprot.org/uniprotkb/G3MZK0" } ], "pmid": "" }, { "name": "cysteamine dioxygenase activity", "id": "GO:0047800", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0047800", "evidence": [ { "database": "UniProtKB", "id": "G3MZK0", "url": "https://www.uniprot.org/uniprotkb/G3MZK0" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 1, "go_terms": [ { "name": "cellular response to hypoxia", "id": "GO:0071456", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0071456", "evidence": [ { "database": "UniProtKB", "id": "G3MZK0", "url": "https://www.uniprot.org/uniprotkb/G3MZK0" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 50, "end_pos": 52, "annotation": "n_glycosylation_sequon" }, { "start_pos": 67, "end_pos": 69, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [ { "id": "14409", "name": "", "equation": "cysteamine + O2 = hypotaurine + H(+)", "summary": "", "cellular_location": "", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [ "G3MZK0-1" ], "evidence": [ { "id": "14409", "database": "Rhea", "url": "https://www.rhea-db.org/rhea/14409" } ] }, { "id": "70895", "name": "", "equation": "N-terminal L-cysteinyl-[protein] + O2 = N-terminal S-hydroxy-S-oxy-L-cysteinyl-[protein] + H(+)", "summary": "", "cellular_location": "", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [ "G3MZK0-1" ], "evidence": [ { "id": "70895", "database": "Rhea", "url": "https://www.rhea-db.org/rhea/70895" } ] }, { "id": "R-BTA-6814153", "name": "ADO oxidises 2AET to HTAU", "equation": "", "summary": "This event has been computationally inferred from an event that has been demonstrated in another species.

The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.

More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "cellular_location": "cytosol", "input_participant_list": [ "R-ALL-6814151" ], "output_participant_list": [], "enzyme_list": [ "G3MZK0-1" ], "evidence": [ { "id": "R-BTA-6814153", "database": "Reactome", "url": "https://www.reactome.org/PathwayBrowser/#R-BTA-6814153" } ] } ], "reaction_participants": [ { "participant_id": "R-ALL-6814151", "participant_name": "2AET [cytosol]", "crossref": [ { "id": "58029", "database": "ChEBI", "url": "" }, { "id": "ZINC000008034121", "database": "ZINC", "url": "" } ] } ], "reaction_enzymes": [ { "uniprot_ac": "G3MZK0", "gene_name": "ADO", "activity": [ { "ec_number": "1.13.11.19", "activity": "cysteamine + O2 = hypotaurine + H(+).", "evidence": [ { "id": "G3MZK0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3MZK0" } ] }, { "ec_number": "1.13.11.19", "activity": "", "evidence": [ { "id": "G3MZK0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3MZK0" } ] } ] } ], "biomarkers": [], "structures": [ { "pdb_id": "AF-G3MZK0-F1", "pdb_chain": "global", "start_pos": 1, "end_pos": 270, "overlap": "1.0", "method": "AlphaFold", "type": "alphafold", "resolution": -1.0, "url": "https://data.glygen.org/ln2downloads/pdb/current/AF-G3MZK0-F1.pdb", "url_external": "https://alphafold.ebi.ac.uk/entry/G3MZK0" } ], "lectin_list": [], "domain_list": [], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [ { "ec_number": "1.13.11.19", "ec_name": "cysteamine + O2 = hypotaurine + H(+).", "evidence": [ { "id": "1.13.11.19", "database": "Rhea", "url": "https://www.rhea-db.org/rhea/?query=ec:1.13.11.19" }, { "id": "1.13.11.19", "database": "BRENDA Enzymes", "url": "https://www.brenda-enzymes.org/enzyme.php?ecno=1.13.11.19" } ] } ], "cluster_types": [], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 50, "end_pos": 52 }, { "start_pos": 67, "end_pos": 69 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ], "tool_support": { "graph_view": "yes" } }, { "uniprot_canonical_ac": "G3MZM9-1", "uniprot_ac": "G3MZM9", "uniprot_id": "G3MZM9_BOVIN", "mass": { "chemical_mass": 40746.0, "monoisotopic_mass": 40746.0 }, "refseq": { "ac": "XP_015316936", "name": "uncharacterized protein CXorf66 homolog", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_015316936" }, "gene_names": [ { "name": "LOC107131211", "type": "recommended", "evidence": [ { "id": "G3MZM9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3MZM9" } ] }, { "name": "LOC107131211", "type": "synonym", "evidence": [ { "id": "XP_015316936", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_015316936" } ] } ], "protein_names": [ { "name": "Uncharacterized protein", "type": "synonym", "evidence": [ { "id": "G3MZM9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3MZM9/entry#names_and_taxonomy" } ] }, { "name": "uncharacterized protein CXorf66 homolog", "type": "synonym", "evidence": [ { "id": "XP_015316936", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_015316936" } ] } ], "function": [], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Bos taurus", "taxid": 9913, "evidence": [ { "database": "UniProtKB", "id": "G3MZM9", "url": "https://www.uniprot.org/uniprotkb/G3MZM9" } ], "common_name": "Bovine", "glygen_name": "Bovine", "reference_species": "Bos taurus [9913]" } ], "gene": [ { "name": "LOC107131211", "url": "https://www.uniprot.org/uniprotkb/G3MZM9", "locus": {} } ], "crossref": [ { "id": "G3MZM9", "url": "https://alphafold.ebi.ac.uk/entry/G3MZM9", "database": "AlphaFoldDB", "categories": [] }, { "id": "ENSBTAG00000047819", "url": "https://bgee.org/?page=gene&gene_id=ENSBTAG00000047819", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "107131211", "url": "https://www.ncbi.nlm.nih.gov/gene/107131211", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR038873", "url": "https://www.ebi.ac.uk/interpro/entry/IPR038873", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "bta:107131211", "url": "https://www.genome.jp/dbget-bin/www_bget?bta:107131211", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "G3MZM9", "url": "https://www.orthodb.org/?gene=G3MZM9", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR37340", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR37340", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR37340:SF1", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR37340:SF1", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF27959", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF27959", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "XP_015316936", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_015316936", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "G3MZM9", "url": "https://www.uniprot.org/uniprotkb/G3MZM9", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "G3MZM9-1", "url": "https://www.uniprot.org/uniprotkb/G3MZM9-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MNLFIYVLLLSIWTSSCLDRNESNGSATAVTTRAEFKQTKLQELRRRLLIIVIGTLITGYMVTCTCLLHYRCDSKEAHKAAKDKKEDITIKASRSSKISFTDSKSPTAGLGDPERQSVVSRIDKSSGPSSPRKVPSSAEKLVRPSSQKKPSKPSAPKKVLGSPPQEKLHRTRSPKKAHRQAHAHKLVSQVSPSYPEKAIKPTWPPSLQCRVKPTKTPLPYPKNQSFPEHSSADKLTKRQRYLKLKCPASAGRAEILSRPQPVKFCRCYKEKCLVCRAVSEPFITHVSEANKKHVPVPLFSRELKHFYKSYKKKQPKYNTLYGNMSDSDITTYNSDGESDREVIIMCNIKCKEDIYKNSPNN", "length": 361, "header": "tr|G3MZM9-1|G3MZM9_BOVIN Isoform 1 of Uncharacterized protein OS=Bos taurus OX=9913 GN=LOC107131211 PE=4 SV=2 CANONICAL=G3MZM9-1" }, "isoforms": [ { "isoform_ac": "G3MZM9-1", "url": "https://www.uniprot.org/uniprotkb/G3MZM9/entry", "sequence": { "sequence": "MNLFIYVLLLSIWTSSCLDRNESNGSATAVTTRAEFKQTKLQELRRRLLIIVIGTLITGYMVTCTCLLHYRCDSKEAHKAAKDKKEDITIKASRSSKISFTDSKSPTAGLGDPERQSVVSRIDKSSGPSSPRKVPSSAEKLVRPSSQKKPSKPSAPKKVLGSPPQEKLHRTRSPKKAHRQAHAHKLVSQVSPSYPEKAIKPTWPPSLQCRVKPTKTPLPYPKNQSFPEHSSADKLTKRQRYLKLKCPASAGRAEILSRPQPVKFCRCYKEKCLVCRAVSEPFITHVSEANKKHVPVPLFSRELKHFYKSYKKKQPKYNTLYGNMSDSDITTYNSDGESDREVIIMCNIKCKEDIYKNSPNN", "length": 361, "header": "tr|G3MZM9-1|G3MZM9_BOVIN Isoform 1 of Uncharacterized protein OS=Bos taurus OX=9913 GN=LOC107131211 PE=4 SV=2 CANONICAL=G3MZM9-1" }, "locus": { "chromosome": "X", "start_pos": 23473350, "end_pos": 23469127, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000063340.2", "url": "https://www.ensembl.org/id/ENSBTAT00000063340.2" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000055030.2", "url": "https://www.ensembl.org/id/ENSBTAP00000055030.2" } ] } } ], "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "other", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 202, "start_aa": "Thr", "end_pos": 202, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr202", "evidence": [ { "id": "", "database": "GlyGen", "url": "https://data.glygen.org/" } ], "filter_code": "000000000000000010000.00000000001000.0.01000" } ], "phosphorylation": [], "glycation": [], "keywords": [ "glycoprotein", "glycoprotein_predicted" ], "publication": [], "pathway": [ { "id": "bta:107131211", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?bta:107131211", "resource": "KEGG Pathway" } ], "orthologs": [ { "uniprot_canonical_ac": "A0A075B5S0-1", "protein_name": "Immunoglobulin heavy variable 16-1", "gene_name": "Ighv16-1", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "EVQLVESGGSLGQPGGSTKLSCEEASGFTFSDHWMDWFRQAPGMRLEWLANTNHDESGKGYAESVKDRFSISRDNSENLLYLQMNSLRNEDTALYYCAR", "length": 99 }, "evidence": [ { "id": "G3MZM9", "url": "https://omabrowser.org/oma/group/G3MZM9/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "A0A075B603-1", "protein_name": "T cell receptor alpha variable 6D-6", "gene_name": "Trav6-6", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MDSSPGFVAVILLILGRTHGDSVTQTEGPVTVSESESLIINCTYSATSIAYPNLFWYVRYPGEGLQLLLKVITAGQKGSSRGFEATYNKETTSFHLQKASVQESDSAVYYCALG", "length": 114 }, "evidence": [ { "id": "G3MZM9", "url": "https://omabrowser.org/oma/group/G3MZM9/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "A0A075B625-1", "protein_name": "T cell receptor alpha variable 4N-3", "gene_name": "Trav4n-3", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MERNLGAVLGILWVQICWVSGDKVKQSPSALSLQEGTNSALRCNFSIAATTVQWFLQNPRGSLMNLFYLVPGTKENGRLKSAFDSKESYSTLHIRDAQLEDSGTYFCAAE", "length": 110 }, "evidence": [ { "id": "G3MZM9", "url": "https://omabrowser.org/oma/group/G3MZM9/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "A0A075B695-1", "protein_name": "T cell receptor alpha variable 9D-3", "gene_name": "Trav9d-3", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MLLALLPVLGIHFLLRDAQAQSVTQPDARVTVSEGASLQLRCKYSYFGTPYLFWYVQYPRQGLQLLLKYYPGDPVVQGVNGFEAEFSKSNSSFHLRKASVHWSDWAVYFCAVS", "length": 113 }, "evidence": [ { "id": "G3MZM9", "url": "https://omabrowser.org/oma/group/G3MZM9/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "A0A075B6B4-1", "protein_name": "T cell receptor alpha variable 6-4", "gene_name": "Trav6-4", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MNTSPVLVTVMLLFMLGMRKTHGDSVTQKQGQVTLSEDDFLFINCTYSTTTYPTLLWYVQYLGQGPQLLLKVTTANNKGISRGFEATYDKGTTSFHLQKASVQESDSAVYFCALV", "length": 115 }, "evidence": [ { "id": "G3MZM9", "url": "https://omabrowser.org/oma/group/G3MZM9/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "A0A075B6D8-1", "protein_name": "T cell receptor alpha variable 3-3", "gene_name": "Trav3-3", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "GEQVEQRPPHLSVREGDSAVITCTYTDPNSYYFFWYKQEPGASLQLLMKVFSSTEINEGQGFTVLLNKKDKRLSLNLTAAHPGDSAAYFCAV", "length": 92 }, "evidence": [ { "id": "G3MZM9", "url": "https://omabrowser.org/oma/group/G3MZM9/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "A0A075B759-1", "protein_name": "Peptidyl-prolyl cis-trans isomerase A-like 4E", "gene_name": "PPIAL4E", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MVNSVVFFEITRDGKPLGRISIKLFADKIPKTAENFRALSTGEKGFRYKGSCFHRIIPGFMCQGGDFTRPNGTGDKSIYGEKFDDENLIRKHTGSGILSMANAGPNTNGSQFFICAAKTEWLDGKHVAFGKVKERVNIVEAMEHFGYRNSKTSKKITIADCGQF", "length": 164 }, "evidence": [ { "id": "G3MZM9", "url": "https://omabrowser.org/oma/group/G3MZM9/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "A0A075B767-1", "protein_name": "Peptidyl-prolyl cis-trans isomerase A-like 4H", "gene_name": "PPIAL4H", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MVNSVVFFDITVDGKPLGRISIKLFADKIPKTAENFRALSTGEKGFRYKGSCFHRIIPGFMCQGGDFTRPNGTDDKSIYGEKFDDENLIRKHTGSGILSMVNAGPNTNGSQLFICTAKTEWLDGKHVAFGKVKERVNIVEAMEHFGYRNSKTSKKITIADCGQF", "length": 164 }, "evidence": [ { "id": "G3MZM9", "url": "https://omabrowser.org/oma/group/G3MZM9/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "A0A087WP50-1", "protein_name": "Secretoglobin, family 1B, member 15", "gene_name": "Scgb1b17", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MMLAGAVVIFGVALLLLSSWGDCGICPAMKEDVHLFLNGTSEEYVEYVKQYKDDPEILENTEKIKQCVDSTLMEEDKAHANGFIEKIEASPLC", "length": 93 }, "evidence": [ { "id": "G3MZM9", "url": "https://omabrowser.org/oma/group/G3MZM9/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "A0A087WPA9-1", "protein_name": "Secretoglobin, family 2B, member 18", "gene_name": "Scgb2b18", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MKGTLLLLGLLVTGELSFQTSEACVSFFEGYASVLSGSRVWLYQELQAFDATAEEKVALEKIQSCYSEERIRNILLEPKIMEAMVASPECRSYHSFNNFRSILDFISNLLGE", "length": 112 }, "evidence": [ { "id": "G3MZM9", "url": "https://omabrowser.org/oma/group/G3MZM9/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "A0A087WPG5-1", "protein_name": "Predicted gene 13283", "gene_name": "Gm13283", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MLPVHLFLVGGVMLSCSPASSLDSGKSGSLHLERSETARFLADLRSVPGHQCLRDRTDFPCPWKEGTNITQMTLGETTSCYSQSLRQVLHRFDTEASRAAWHERALDQLLSSLWRELQVLKRPREQGQSCPLPFALAIRTYFRGFFRYLKAKAHSACSWEIVRVQLQVDLPAFPLSARRGPR", "length": 182 }, "evidence": [ { "id": "G3MZM9", "url": "https://omabrowser.org/oma/group/G3MZM9/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "A0A087WPY7-1", "protein_name": "RNA binding motif protein Y-linked family member 4", "gene_name": "Rbmyf4", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MAETNQPGKIFIGGLNIKTRQKTLQEIFGRFGPVARVILMRDRETKKSRGFAFLTFRRLADAKNAVKEMNGVILDGKRIKVKQARRPSSLESGSKKRPPSFSRTRGASRILKCGRGGRSRARSGPSCEGNLGGDRYTPNFNVSSSGRHFAVKRNPSSKRDDPPSKR", "length": 166 }, "evidence": [ { "id": "G3MZM9", "url": "https://omabrowser.org/oma/group/G3MZM9/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "A0A087WQA9-1", "protein_name": "Secretoglobin, family 2B, member 21", "gene_name": "Scgb2b21", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MKGTLLLLGLLVTGELSFQTTEACVPFFEGYASVVSGSRVWMYQEFQAFDATAEEKVALEKIQGCYREESLRNILLEPKIMEAMVASPECLSYYSSNNIRCILDLLSKLLGQ", "length": 112 }, "evidence": [ { "id": "G3MZM9", "url": "https://omabrowser.org/oma/group/G3MZM9/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "A0A087WQJ0-1", "protein_name": "Secretoglobin, family 1B, member 11", "gene_name": "Scgb1b11", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MKLVAAVVILGAALLLLTSGGDCGICPAIKEDVRLFLNGTSEEYVEYVKQYKDDPVILENTAKINQCVDSTLTEKDMTHTTTFLKKIEDSLLC", "length": 93 }, "evidence": [ { "id": "G3MZM9", "url": "https://omabrowser.org/oma/group/G3MZM9/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "A0A087WQP8-1", "protein_name": "Predicted gene, 21698", "gene_name": "Gm21698", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MALFARLCRLFQRVNVDGRETREGRKDADLPSERNEGRRRWTWRMCMAHGQTTSPVPVKSKKQFEKEEKELIKKIQLTTEETNELRDRLIYVTKGSMNKRPYHRQTRHYKELKLKEKEIMTFLHDLEMKNMEARENNQELKKEKNFYRNLHTRILLGENLIKKKLAILQQESKEIHADWAIIQQRLVELNLSGKDEQEKTSNLEAQENQVSEAARELGLATAEEDSILQNELPCQEAPAEHHPQHPSSSSDESSSDESSYSTCPEWE", "length": 267 }, "evidence": [ { "id": "G3MZM9", "url": "https://omabrowser.org/oma/group/G3MZM9/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "A0A087WR36-1", "protein_name": "Vomeronasal type-1 receptor", "gene_name": "Vmn1r90", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MSSQNEAMKTTEEVALQIVLLCQFGIGTMANILLFIHNFSPLLTGCQLRPKQVICTNMAVSSILILFMTVFPNNVFVVQRNLMNDLQCKLEYFLRMVARSINLCSTCVLSTYQFVTLLPGNFGEMMVRGRRSKVISYSCCSCWLFGVLYNVYIPMKVSGPQNTHNKTDIKSKWFCVTSGFSVGIMFLWFAHDAIFISIMIWTSVSMVLLLYRHYQRLQYIFPPHQGTRGYAEIRAAHSIAMLVVTFVSFYLLHCICFILHIVFVDSRLWLRHVGEVLTSSFPTISPLLLIFRDPSYPCSLIFNYRKPVI", "length": 309 }, "evidence": [ { "id": "G3MZM9", "url": "https://omabrowser.org/oma/group/G3MZM9/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "A0A087WR44-1", "protein_name": "BTB domain containing 35, family member 15", "gene_name": "Btbd35f15", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MGLLVSRVLRCRDSSLLEPQPEAIAGASYIPGSRKRKRNSLEELATSSNVHGPQNQGMYPHQVLNYIYWKRVKISSNDAYQNLFLDGHDSDIKIHALGKTWCLHKVFLCQSGYFANILKGTWRESHHGVINLIIKNEDIDTRSLHFVFGALYTDADLSITPLEVPQVLAAACLLRVDRVIQQCEGIMKETINRNTVCSYYLAAETYRLKAVKTRCFEWLLCNLMVHPSVALYKEVDLKLMYVLALSSDLLVMQKEIDVYTTLKIWMFLYLNPCWNGTMKQLLQHANNWLSTHMAYVDNISFLESEEGLIFQPVFKKLRFQHIICDLTSTTILEQDRLIPMAWLSPIYKQQWLTLLRTQEYGVIGPQVINEQELEECTMRCGTMIPKDGRYTWKWSVGRLGFPLRVTFTRQCVILRQRCQRCDGSACHNHIRNVIFRITLVCFDSNKRVTFRKTTGYKILTFEYKEEQIVMKLDSDVLTFPMCIFCNFLFVNLGNAENK", "length": 498 }, "evidence": [ { "id": "G3MZM9", "url": "https://omabrowser.org/oma/group/G3MZM9/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "A0A087WR49-1", "protein_name": "Secretoglobin, family 2B, member 11", "gene_name": "Scgb2b11", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MKGTLLLLGLLVTGELSFQTSEACVSFFEGYASVLSGSRVWLYQELQAFDATAEEKVALEKIQGCYSEERIRNILLEPKIMEAMVASPECRSYHSLNNFRSILEFISNLLGE", "length": 112 }, "evidence": [ { "id": "G3MZM9", "url": "https://omabrowser.org/oma/group/G3MZM9/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "A0A087WSM5-1", "protein_name": "Predicted gene 29049", "gene_name": "Gm29049", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MTSLKKKSRRKPSSQALGNIVGCRISYGWKEGNEPVTHWKAIILGQLPTNPSLYLVKYDGIDSVYGQELHSDERILNLKVLPHKVVFLQVRDVHLASALVCREVQHKFEGKDGSEDNWSGMVLAQVPFLQDYFYISYKKDPVLYVYQLLDDYKEGNLHIIPETPLAEARSGDDNDFLIGSWVQYTRDDGSKKFGKVVYKVLANSTVYCIKFLGDLHIYVYTLVSNIT", "length": 227 }, "evidence": [ { "id": "G3MZM9", "url": "https://omabrowser.org/oma/group/G3MZM9/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "A0A087WSN2-1", "protein_name": "BTB domain containing 35, family member 16", "gene_name": "Btbd35f16", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MGLLVSRVLRCRDSSLLEPQPEAIAGASYIPGSRKRKRNSLEELATSSNVHGPQNQGMYPHQVLNYIYWKRVKISSNDAYQNLFLDGHDSDIKIRALGKTWCLHKVFLCQSGYFANILKGTWRESHHGVINLIIKNEDIDTRSLLFVFGALYTDADLSITPLEVPQVLAAACLLRVDRVIQQCEGIMKETINRNTVCSYYLAAETYRLKAVKTRCFEWLLCNLMVHPSVALYKEVDLKLMYLLALSSDLLVMQKEIDVYTTLKIWMFLYLNPCWNGTMKQLLQHANNWLSTHMAYVDNISFLESEEGLIFQPVFKKLRFQHIICDLTSTTILEQDRLIPMAWLSPIYKQQWLTLLRTQEYGVIGPQVINEQELEECTMRCGTMIPKDGRYTWKWSVGRLGFPLRVTFTRQCVILRQRCQRCDGSACHNHIRNVIFRITLVCFDSNKRVTFRKTTGYKILTFEYKEEQIVMKLDSDVLNFPMCIFCNFLFVNLGNAENK", "length": 498 }, "evidence": [ { "id": "G3MZM9", "url": "https://omabrowser.org/oma/group/G3MZM9/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "A0A087WUL8-1", "protein_name": "NBPF family member NBPF19", "gene_name": "NBPF19", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MVVSAGPWSSEKAEMNILEINETLRPQLAEKKQQFRNLKEKCFLTQLAGFLANRQKKYKYEECKDLIKFMLRNERQFKEEKLAEQLKQAEELRQYKVLFHSQERELTQLREKLREGRDASRSLNEHLQALLTPDEPDKSQGQDLQEQLAEGCRLAQHLVQKLSPENDNDDDEDVQVEVAEKVQKSSAPREMQKAEEKEVPEDSLEECAITYSNSHGPYDSNQPHRKTKITFEEDKVDSTLIGSSSHVEWEDAVHIIPENESDDEEEEEKGPVSPRNLQESEEEEVPQESWDEGYSTLSIPPEMLASYQSYSSTFHSLEEQQVCMAVDIGRHRWDQVKKEDQEATGPRLSRELLDEKGPEVLQDSLDRCYSTPSGCLELTDSCQPYRSAFYVLEQQRVGLAIDMDEIEKYQEVEEDQDPSCPRLSRELLDEKEPEVLQDSLDRCYSIPSGYLELPDLGQPYSSAVYSLEEQYLGLALDVDRIKKDQEEEEDQDPPCPRLSRELVEVVEPEVLQDSLDRCYSTPSSCLEQPDSCQPYGSSFYALEEKHVGFSLDVGEIEKKGKGKKRRGRRSKKERRRGRKEGEEDQNPPCPRLSRELLDEKGPEVLQDSLDRCYSTPSGCLELTDSCQPYRSAFYILEQQCVGLAVDMDEIEKYQEVEEDQDPSCPRLSRELLDEKEPEVLQDSLDRCYSIPSGYLELPDLGQPYSSAVYSLEEQYLGLALDVDRIKKDQEEEEDQDPPCPRLSRELVEVVEPEVLQDSLDRCYSTPSSCLEQPDSCQPYGSSFYALEEKHVGFSLDVGEIEKKGKGKKRRGRRSKKERRRGRKEGEEDQNPPCPRLSRELLDEKGPEVLQDSLDRCYSTPSGCLELTDSCQPYRSAFYILEQQCVGLAIDMDEIEKYQEVEEDQDPSCPRLSRELLDEKEPEVLQDSLDRCYSIPSGYLELPDLGQPYSSAVYSLEEQYLGLALDVDRIKKDQEEEEDQDPPCPRLSRELVEVVEPEVLQDSLDRCYSTPSSCLEQPDSCQPYGSSFYALEEKHVGFSLDVGEIEKKGKGKKRRGRRSKKERRRGRKEGEEDQNPPCPRLSRELLDEKGPEVLQDSLDRCYSTPSGCLELTDSCQPYRSAFYILEQQCVGLAVDMDEIEKYQEVEEDQDPSCPRLSRELLDEKEPEVLQDSLDRCYSIPSGYLELPDLGQPYSSAVYSLEEQYLGLALDVDRIKKDQEEEEDQDPPCPRLSRELVEVVEPEVLQDSLDRCYSTPSSCLEQPDSCQPYGSSFYALEEKHVGFSLDVGEIEKKGKGKKRRGRRSKKERRRGRKEGEEDQNPPCPRLSRELLDEKGPEVLQDSLDRCYSTPSGCLELTDSCQPYRSAFYILEQQCVGLAVDMDEIEKYQEVEEDQDPSCPRLSRELLDEKEPEVLQDSLDRCYSIPSGYLELPDLGQPYSSAVYSLEEQYLGLALDVDRIKKDQEEEEDQDPPCPRLSRELVEVVEPEVLQDSLDRCYSTPSSCLEQPDSCQPYGSSFYALEEKHVGFSLDVGEIEKKGKGKKRRGRRSKKERRRGRKEGEEDQNPPCPRLSRELLDEKGPEVLQDSLDRCYSTPSGCLELTDSCQPYRSAFYILEQQCVGLAVDMDEIEKYQEVEEDQDPSCPRLSRELLDEKEPEVLQDSLDRCYSIPSGYLELPDLGQPYSSAVYSLEEQYLGLALDVDRIKKDQEEEEDQDPPCPRLSRELLEVVEPEVLQDSLDRCYSTPSSCLEQPDSCQPYGSSFYALEEKHVGFSLDVGEIEKKGKGKKRRGRRSKKERRRGRKEGEEDQNPPCPRLSRELLDEKGPEVLQDSLDRCYSTPSGCLELTDSCQPYRSAFYILEQQCVGLAVDMDEIEKYQEVEEDQDPSCPRLSRELLDEKEPEVLQDSLDRCYSTPSGYLELPDLGQPYSSAVYSLEEQYLGLALDVDRIKKDQEEEEDQGPPCPRLSRELLEVVEPEVLQDSLDRCYSTPSSCLEQPDSCQPYGSSFYALEEKHVGFSLDVGEIEKKGKGKKRRGRRSKKERRRGRKEGEEDQNPPCPRLSRELLDEKGPEVLQDSLDRCYSTPSGCLELTDSCQPYRSAFYILEQQCVGLAVDMDEIEKYQEVEEDQDPSCPRLSRELLDEKEPEVLQDSLDRCYSTPSGYLELPDLGQPYSSAVYSLEEQYLGLALDVDRIKKDQEEEEDQGPPCPRLSRELLEVVEPEVLQDSLDRCYSTPSSCLEQPDSCQPYGSSFYALEEKHVGFSLDVGEIEKKGKGKKRRGRRSKKERRRGRKEGEEDQNPPCPRLSRELLDEKGPEVLQDSLDRCYSTPSGCLELTDSCQPYRSAFYILEQQCVGLAVDMDEIEKYQEVEEDQDPSCPRLSRELLDEKEPEVLQDSLDRCYSTPSGYLELPDLGQPYSSAVYSLEEQYLGLALDVDRIKKDQEEEEDQGPPCPRLSRELLEVVEPEVLQDSLDRCYSTPSSCLEQPDSCQPYGSSFYALEEKHVGFSLDVGEIEKKGKGKKRRGRRSKKERRRGRKEGEEDQNPPCPRLSRELLDEKGPEVLQDSLDRCYSTPSGCLELTDSCQPYRSAFYILEQQCVGLAVDMDEIEKYQEVEEDQDPSCPRLSRELLDEKEPEVLQDSLDRCYSTPSGYLELPDLGQPYSSAVYSLEEQYLGLALDVDRIKKDQEEEEDQGPPCPRLSRELLEVVEPEVLQDSLDRCYSTPSSCLEQPDSCQPYGSSFYALEEKHVGFSLDVGEIEKKGKGKKRRGRRSKKERRRGRKEGEEDQNPPCPRLSRELLDEKGPEVLQDSLDRCYSTPSGCLELTDSCQPYRSAFYILEQQCVGLAVDMDEIEKYQEVEEDQDPSCPRLSRELLDEKEPEVLQDSLDRCYSTPSGYLELPDLGQPYSSAVYSLEEQYLGLALDVDRIKKDQEEEEDQGPPCPRLSRELLEVVEPEVLQDSLDRCYSTPSSCLEQPDSCQPYGSSFYALEEKHVGFSLDVGEIEKKGKGKKRRGRRSKKERRRGRKEGEEDQNPPCPRLSRELLDEKGPEVLQDSLDRCYSTPSGCLELTDSCQPYRSAFYILEQQCVGLAVDMDEIEKYQEVEEDQDPSCPRLSRELLAEKEPEVLQDPLDRCYSTPSGYLELPDLGQPYSSAVYSLEEQYLGLALDVDRIKKDQEEEEDQGPPCPRLSRELLEVVEPEVLQDSLDRCYSTPSSCLEQPDSCQPYGSSFYALEEKHVGFSLDVGEIEKKGKGKKRRGRRSKKERRRGRKEGEEDQNPPCPRLSRELLDEKGPEVLQDSLDRCYSTPSGCLELTDSCQPYRSAFYILEQQCVGLAVDMDEIEKYQEVEEDQDPSCPRLSRELLAEKEPEVLQDPLDRCYSTPSGYLELPDLGQPYSSAVYSLEEQYLGLALDVDRIKKDQEEEEDQGPPCPRLSRELLEVVEPEVLQDSLDRCYSTPSSCLEQPDSCQPYGSSFYALEEKHVGFSLDVGEIEKKGKGKKRRGRRSKKERRRGRKEGEEDQNPPCPRLSRELLDEKGPEVLQDSLDRCYSTPSGCLELTDSCQPYRSAFYILEQQCVGLAVDMDEIEKYQEVEEDQDPSCPRLSRELLAEKEPEVLQDPLDRCYSTPSGYLELPDLGQPYSSAVYSLEEQYLGLALDVDRIKKDQEEEEDQGPPCPRLSRELLEVVEPEVLQDSLDRCYSTPSSCLEQPDSCQPYGSSFYALEEKHVGFSLDVGEIEKKGKGKKRRGRRSKKERRRGRKEGEEDQNPPCPRLNSVLMEVEEPEVLQDSLDGCYSTPSMYFELPDSFQHYRSVFYSFEEEHISFALYLDNRFFTLTVTSLHLVFQMLVIFPQ", "length": 3843 }, "evidence": [ { "id": "G3MZM9", "url": "https://omabrowser.org/oma/group/G3MZM9/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "A0A087WXS9-1", "protein_name": "TBC1 domain family member 3I", "gene_name": "TBC1D3I", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MDVVEVAGSWWAQEREDIIMKYEKGHRAGLPEDKGPKPFRSYNNNVDHLGIVHETELPPLTAREAKQIRREISRKSKWVDMLGDWEKYKSSRKLIDRAYKGMPMNIRGPMWSVLLNTEEMKMKNPGRYQIMKEKGKRSSEHIQRIDRDVSGTLRKHIFFRDRYGTKQRELLHILLAYEEYNPEVGYCRDLSHIAALFLLYLPEEDAFWALVQLLASERHSLQGFHSPNGGTVQGLQDQQEHVVATSQPKTMGHQDKKDLCGQCSPLGCLIRILIDGISLGLTLRLWDVYLVEGEQALMPITRIAFKVQQKRLTKTSRCGPWARFCNRFVDTWARDEDTVLKHLRASMKKLTRKQGDLPPPAKPEQGSSASRPVPASRGGKTLCKGDRQAPPGPPARFPRPIWSASPPRAPRSSTPCPGGAVREDTYPVGTQGVPSPALAQGGPQGSWRFLQWNSMPRLPTDLDVEGPWFRHYDFRQSCWVRAISQEDQLAPCWQAEHPAERVRSAFAAPSTDSDQGTPFRARDEQQCAPTSGPCLCGLHLESSQFPPGF", "length": 549 }, "evidence": [ { "id": "G3MZM9", "url": "https://omabrowser.org/oma/group/G3MZM9/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "A0A087X179-1", "protein_name": "TBC1 domain family member 3E", "gene_name": "TBC1D3E", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MDVVEVAGSWWAQEREDIIMKYEKGHRAGLPEDKGPKPFRSYNNNVDHLGIVHETELPPLTAREAKQIRREISRKSKWVDMLGDWEKYKSSRKLIDQAYKGMPMNIRGPMWSVLLNTEEMKLKNPGRYQIMKEKGKKSSEHIQRIDRDVSGTLRKHIFFRDRYGTKQRELLHILLAYEEYNPEVGYCRDLSHIAALFLLYLPEEDAFWALVQLLASERHSLQGFHSPNGGTVQGLQDQQEHVVATSQPKTMGHQDKKDLCGQCSPLGCLIRILIDGISLGLTLRLWDVYLVEGEQALMPITRIAFKVQQKRLTKTSRCGPWARFCNRFVDTWARDEDTVLKHLRASMKKLTRKKGDLPPPAKPEQGSSASRPVPASRGGKTLCKGDRQAPPGPPARFPRPIWSASPPRAPRSSTPCPGGAVREDTYPVGTQGVPSPALAQGGPQGSWRFLQWNSMPRLPTDLDVEGPWFRHYDFRQSCWVRAISQEDQLAPCWQAEHPAERVRSAFAAPSTDSDQGTPFRARDEQQCAPTSGPCLCGLHLESSQFPPGF", "length": 549 }, "evidence": [ { "id": "G3MZM9", "url": "https://omabrowser.org/oma/group/G3MZM9/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "A0A0A0MQP3-1", "protein_name": "BTB domain containing 35, family member 12", "gene_name": "Btbd35f12", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MGLLVSRVLRCRDSSLLEPQPEAIAGASYIPGSRKRKRNSLEELATSSNVHGPQNQGMYPHQVLNYIYWKRVKISSNDAYQNLFLDGHDSDIKIRALGRTWCLHKVFLCQSGYFANILKGTWRESHHGVINLIIKNEDIDTRSLHFVFGALYTDSDLSITPLEVPQGLAAACLLRVDRVIQQCEGIMKETINRNTVCSYYLAAETYRLKAVKTRCFEWLLCNLMVHPSVALYKEVDLKLMYVLALSSDLLVMQKEIDVYTTLKIWMFLYLNPCWNGTMKQLLQHANNWLSTHMAYVDNISFLESEEGLIFQPVFKKLRFQHIICDLTSTTILEQDRLIPMAWLSPIYKQQWLTLLRTQEYGVIGPQVINEQELEECTMRCGTMIPKDGRYTWKWSVGRLGFPLRVTFTRQCVILRQRCQRCDGSACHNHIRNVIFRITLVCFDSNKRVTFRKTTGYKILTFEYKEEQIVMKLDSDVLTFPMCIFCNFLFVNLGNAENK", "length": 498 }, "evidence": [ { "id": "G3MZM9", "url": "https://omabrowser.org/oma/group/G3MZM9/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "A0A0A6YW58-1", "protein_name": "Immunoglobulin heavy variable V8-2", "gene_name": "Ighv8-2", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MGRLTFSFLLLLPVPAYVLSQVTLKVSGPGILQPSQTLSLACTFSGISLSTSGMGLSWLRKPSGKALEWLASIWNNDNYYNPSLKSRLTISKETSNYQVFLKLTSVDTADSATYYGAWR", "length": 119 }, "evidence": [ { "id": "G3MZM9", "url": "https://omabrowser.org/oma/group/G3MZM9/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "A0A0A6YXW2-1", "protein_name": "Predicted gene, 20773", "gene_name": "Gm20773", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MSSLMKKRRRKSSSNTLRNIVGCRISHSWKEGNEPVTQWKAIVLDQLPTNPSLYLVKYDGIDSIYGLELYSDDRILNLKVLPPIVVFPQVRDAHLARALVGRAVQHKFEGKDGSEVNWRGVVLAQVPIMKDLFYITYKKDPALYAYQLLDDYKEGNLHMIPDTPPAEERSGDDSDVLIGNWVEYTRKDGSKKFGKVVYQVLANPSVYFIKFHGDIHIYVYTMVPKIFKVEKS", "length": 232 }, "evidence": [ { "id": "G3MZM9", "url": "https://omabrowser.org/oma/group/G3MZM9/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "A0A0A6YXX7-1", "protein_name": "Predicted gene, 20807", "gene_name": "Gm20807", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MSSLMKKRRRKSSSNTLRNIVGCRISHSWKEGNEPVTQWKAIVLDQLPTNPSLYLVKYDGIDSIYGLELYSDDRILNLKVLPPIVVFPQVRDAHLARALVGRAVQHTFEGKDGSEVNWRGVVLAQVPIMKDLFYITYKKDPALYAYQLLDDYKEGNLHMIPDTPPAEERSGDDSDVLIGNWVEYTRKDGSKKFGKVVYQVLANPSVYFIKFHGDIHIYVYTMVPKVLEVEKS", "length": 232 }, "evidence": [ { "id": "G3MZM9", "url": "https://omabrowser.org/oma/group/G3MZM9/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "A0A0B4J1J8-1", "protein_name": "T cell receptor gamma, variable 4", "gene_name": "Trgv4", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MKNPGSQALLPLYLPWEANLADENPLLKVVIFLCLLTFGHGKLEQPEISISRPRDETAQISCKVFIESFRSVTIHWYRQKPNQGLEFLLYVLATPTHIFLDKEYKKMEASKNPSASTSILTIYSLEEEDEAIYYCSYG", "length": 138 }, "evidence": [ { "id": "G3MZM9", "url": "https://omabrowser.org/oma/group/G3MZM9/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "A0A0G2JE01-1", "protein_name": "Predicted gene, 21663", "gene_name": "Gm21663", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MALFARLCRLFQRVNVDGRETREGRKDADPPSERNEGRRRWTWRMCMAHRQTTSPVPVKSKKQFEKEEKELIKKIQLTTEETNELRDRLIYVTEGSMNKRPYHRQTRHYKELKLKEKEIMTFLHDLEMKNMEARENNQELKKEKNFYRNLHTRILLGENLIKKKLAILQQESKEIHADWAIIQQRLVELNLSGKDEQEKTSNLEAQENQVSEAARELGLATAEEDSILQNELPCQEAPAEHHPQHPSSSSDESSSDESSYSTCPEWE", "length": 267 }, "evidence": [ { "id": "G3MZM9", "url": "https://omabrowser.org/oma/group/G3MZM9/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "A0A0G2JGR8-1", "protein_name": "Predicted gene, 21680", "gene_name": "Gm21680", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MALFARLCRLFQRANVDGRETREGRKDADLPSESNEGRRRWTWRMWMAHRQTTSPVPVTSKKQFEKEEKELIKKIQLTTKEINELRDRLIYVTKGSMNKRPYHRQTRHYKELKLKEKEIMTYLHELEMKNMEARENKQELKKEKNFYRNLHTRILLEENLIKKKLVILQQESKEVHADWATIHQSLVELNLSGKDEQEKTSNLETQEHQVSEAARELVLATAEEDSILQNELPCQEAPAEHHPQHPPSSSDESSSDESSYSTCPEWE", "length": 267 }, "evidence": [ { "id": "G3MZM9", "url": "https://omabrowser.org/oma/group/G3MZM9/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "A0A0G2JMD5-1", "protein_name": "PRAME family member 33", "gene_name": "PRAMEF33", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MSLQAPSRLLELAGQSLLRNQFLTIFTLDELPREVFPLMFMEAFSMRRFEALKLMVQAWPFLRLPLGSLMKTPHLETLQAVLRGLDTLVAQKVRPRRWKLQVLDLQDVDENFWTIWSGARVLSCSPEAMSKRQTVEDCPRMGEHQPLKVFIDLCLKESTLDECLSYLFGWIHYRRGLVHLCCSKVQNYSMPTSSFRNLLERIYPDSIQELEVWKKCSLNKTGKFAPYLSQMSNLRELFLAFGYERELYVSVQWPCIPDLDSPFLCLYYPQMLYIKKISNIKEHLEHLLRYLKNPLGAFIFSDAYLADRDMECLSQYPSLSQLKELRLIHILMWTTNLQPLGALLEKVAATLKTLVLKDCRIQDPQLRVLLPALSHCSQLTTFNFHGNETSMNALKDLLRHTRGLSKLGLELYPAPLESLDYKGHVNWEILTPIRAELMRTLREVRQPKRIFFGPVPCPTCGSWPSEKVDFHLCS", "length": 474 }, "evidence": [ { "id": "G3MZM9", "url": "https://omabrowser.org/oma/group/G3MZM9/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "A0A0G2JNH3-1", "protein_name": "Olfactory receptor", "gene_name": "LOC124905359", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MKIANNTVVTEFILLGLTQSQDIQLLVFVLILIFYLIILPGNFLIIFTIRSDPGLTAPLYFFLGNLAFLDASYSFIVAPRMLVDFFSEKKVISYRGCITQLFFLHFLGGGEGLLLVVMAFDRYIAICRPLHCSTVMNPRACYAMMLALWLGGFVHSIIQVVLILRLPFCGPNQLDNFFCDVRQVIKLACTDMFVVELLMVFNSGLMTLLCFLGLLASYAVILCHVRRAASEGKNKAMSMCTTRVIIILLMFGPAIFIYMCPFRALPADKMVSLFHTVIFPLMNPMIYTLRNQEVKTSMKRLLSRHVVCQVDFIIRN", "length": 316 }, "evidence": [ { "id": "G3MZM9", "url": "https://omabrowser.org/oma/group/G3MZM9/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "A0A0G2JTV6-1", "protein_name": "RIKEN cDNA 4931429L15 gene like", "gene_name": "4931429L15Rikl", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MQFNPFSQDTWRHGHRRAYSNISERLSCLTLQEPSVSHLYQIFSPGDRRSYLLDDSLSNSIQRESLAVPMGLEDSGSRGQQKQQQPGAVLEDLEEQEIAPTDVKYRLQLLDEAPLRSKSSSVQSQGHKPGWIPSSKTHREWFKPWKMDMTYPENERSHSGHTQGRRMTPRAQWRHVEYDSQDQDTQSPVWSQALFPGLDKSSQGVIQCTQHVSREREMVSGWSMTHAPQEMGQAKQGPAFLKTKGTAKFNVATTARMSCLPPLKLLEKKVKSRCPPNTPGIFQDWRAQPQGLYGSDERLLAPFEDQVNTRVTYMPLFTEKVKFVSPKTAVSNPKQTHSQLSRTNQPAFPGQFRNWTSGREHLEKGLPE", "length": 368 }, "evidence": [ { "id": "G3MZM9", "url": "https://omabrowser.org/oma/group/G3MZM9/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "A0A0G2JVP7-1", "protein_name": "40S ribosomal protein S26", "gene_name": "Rps26-ps4", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MTKKRRNNGRTKKGRGHVQPIGCANCSWCVPKDKAIKKFVIWNIVETAAVRDISEARIFDAYVLPKLYVKLHYCVSLAIHSKVIRNQSHEARKDRTSPPRFRPAGAAPRPPPKPM", "length": 115 }, "evidence": [ { "id": "G3MZM9", "url": "https://omabrowser.org/oma/group/G3MZM9/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "A0A0G2JW93-1", "protein_name": "High mobility group protein B4", "gene_name": "Hmgb4l4", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MGKDSKVRPKVNVSPYVHFMMDFRNQTREQQPNTYYDFTEFSRKCSEKWKTISKKEKKKYEALAKRDKDRYQREMRNYSGPRRERRRRDPDAPRKPPSSFLLFSQDHFDEIKEQHPNWTVAQVAKAAGRMWARCSEADKIPYEERAAVLRAKYLEEREAYYHQCQRGE", "length": 168 }, "evidence": [ { "id": "G3MZM9", "url": "https://omabrowser.org/oma/group/G3MZM9/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "A0A0G2JW96-1", "protein_name": "Zinc finger protein 94 like 1", "gene_name": "Zfp94l1", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MLPRGSCDVMLESLRNVASLGHRIGTPDGLLRLKREDMFWLLTVARWSSGSMGDKNLEDMEFLEEVGLRHLPHEELFCSQIWQRITRELTKVRDCRVRVGENGSPMKRDNREDEYSKHSSQNSVFQVHHRECHEEEANERDFGCSHHLRTSTGEKSYKCEKCHNASHWFSSLQSHQGVCDRPRWNKSVSQFKIFRQWPLFHYQQSMPNGENAQEYEACGNAGKNSSGQTALFVHTAEEPYSCEECGARFSQSSYLQVHQRVHTGEKPYKCEECGKGFGWLSQLHAHHQSHTGEKPYTCDACGKGFSYSSHLNIHCRIHTGEKPYQCEECGKGFSQASNLLAHQRGHTGEKPYQCDACGKGFSRISDFNIHIRVHTGEKPYKCEECGKGFSQASNLLAHQRGHTGEKPYKCNTCGKSFRRSSDLNVHCRIHTGEKPYRCEKCDKVFSQFSSLQVHQRVHTGEKPYQCSECGKGFSVGSQLQAHQRCHTGERPYQCEECGKGFCRASNFLAHHGVHTGEKPYRCDMCGKHFRQRSYLQAHHRVHTGEKQFRCEECGKGFSWSSYLQAHQRVHMGEKPYKCEECGKGFSWSSSLLTHQRVHAEDEGQKDLSSSGGSYRK", "length": 616 }, "evidence": [ { "id": "G3MZM9", "url": "https://omabrowser.org/oma/group/G3MZM9/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "A0A0G2JYP5-1", "protein_name": "Olfactory receptor", "gene_name": "Or8g52b", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MPEGNHSRVTEFILTGLTDKPELQLPLFLLFLGIYLLTVLGNLGMIILILLSSHLQTPMYFFLSGLSFIDLGYSTVIIPKMLVNFVTEKNVISYPGCMTQLYCFIAFVLCECYMLSAMAFDRYVAICNPLRYNVTMSYQVCFWMIGGVYSIGFIEATIHTVCMLQVFFCKANVVNHFFCDLLPLFQLACSSTFVNETVLLCLSTLNFCVPTLTILSSYSFIIARIIRIKSTESRFKAFSTCSSHFSSVAVFFGSLGFVYFQPSSVSSKDQGKVSSVFYTIIVPMLNPLIYSLRNKDVKLALNKLFQKKIFHM", "length": 312 }, "evidence": [ { "id": "G3MZM9", "url": "https://omabrowser.org/oma/group/G3MZM9/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "A0A0G2K381-1", "protein_name": "Killer cell lectin-like receptor, subfamily A, member 4", "gene_name": "Klra4", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MSEQEVTYSTLRFHNSSGLQNQVKTNETQGPRETGHRGCSVSWHLIMIPLGILCSILLVTVAVLVTHIFQYSQEKHELQEALNKLHHNYSTMQNESYLNEEMLGNKSSECDAYKSVLDSLNRQQNTCLRLTNIVLDCLQHKGRQVNVHLFCCGIKCYYFIMDKKQWKECEQACQGCKLSLLTIDDEDELKFLQLQVTPDSYWIGLSYDNKKHDSAWIDNNPSKL", "length": 224 }, "evidence": [ { "id": "G3MZM9", "url": "https://omabrowser.org/oma/group/G3MZM9/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "A0A0G2K3S0-1", "protein_name": "Olfactory receptor", "gene_name": "Or4c109", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MYNQSFVNEFILLGLSQNPQIKKISFVIFLLVYIATLVGNMMIVVTIAYSPALLGSPMYFFLAVLSFLDACVSSVVTPKMIVDMVYERKSISFECCMTQVFAVHFLTAVEVIVLAAMAYDRYVAICKPLHYSSIMNRRLCGTLVGVAWAGGFLHSIIQIAFTLPLPFCGPNVIDHFICDLFPLLKLACTDTHIFIILVFANSGSICIIIFSFLLISYGVILFALRAHSSEGRRKALSTCGSHITVVVFFFVPCILIYARPTSAFSFEKNVFVFTDVLTPLLNPMVYTFRNKEMINAIRKMWKRLIVVSDKY", "length": 311 }, "evidence": [ { "id": "G3MZM9", "url": "https://omabrowser.org/oma/group/G3MZM9/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "A0A0G2K622-1", "protein_name": "Histone RNA hairpin-binding protein", "gene_name": "Slbpl", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MSLSSRMEMVSVGVTTEPCHARWEVETDEVVLRRRQKQIDYGKCTPGYQSFLQQVPRAQRQPGFHPQTPNKNRRYSRRSWDAQIRQWRRALHTWDPPSQPLHDRQAEGKAAGNFLRPVDTAPLDDLLDNWPQDPESSENWDRGEKEAQFAYLKVPASCPPQLKDELLHH", "length": 169 }, "evidence": [ { "id": "G3MZM9", "url": "https://omabrowser.org/oma/group/G3MZM9/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "A0A0G2K698-1", "protein_name": "Lamin tail domain containing 1", "gene_name": "Lmntd1", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MSHLASSHRVQKSSLARPERRAKSPSYTDISFWVPVMHRVGSQYQFESVCEQSSGYPGMPAQQVTPVPSQRGGILRKEEKTGTITPSKQHSSVHFFPKVMDSSSTLHLLSGSFSHEASANFHQIPSAQDSLSPGGLLTSKSNVPSCSRKDSIPGKQSTHQAASPGTSLMTLKKQPKPSSDLDTYVLGDGEDYFLSLFGDSKKLTSHTSQAEDVSKHLSVILEEVGQFVSSSLGDIKIAEVNVKGFFVRLVNSSNEKEVEIGNYILQQNVNGQAVSLYRFPHNITMQASGTVTVWAAASEAKPQQPTDFVWEEQSRFRSSPDCTTILCKPSGEAIAWYTPIHWKQAWEKLETDIEFERCSVVIPSLKSHIFGRTTSSVSSINKEKQEPTQKTPPQVCSVLLREKEILLTVLPNKSPWCRSPDTPPHPYSSLIEWHDSDFPGSSLGTQPKPQSTKPKPDPGTKEKKSTR", "length": 467 }, "evidence": [ { "id": "G3MZM9", "url": "https://omabrowser.org/oma/group/G3MZM9/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "A0A0G2K6E6-1", "protein_name": "Rho GTPase-activating protein 20-like", "gene_name": "LOC120093152", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MGEIHRTLLCQGPVELTSGRKRNKRYLSLFDDVLVVSTNLTKKKFKIKCIIPLNYLWVVDDEELVRANKTCTCKTIFFYWATGNALATFRSEEQKVQWYTFLTSRSISEAKKGIKKTFPLHIFPEDIQTCDSSLCVTATNMDTVNDIMEKLLPMIRVHKIEDYQLWFSPGHKEAPRALQGHEYPYDIIMNNVQNNLSKSNSKIFTAFPPLPGLFMENQSWDTGGQFILKPRDSAGSQQQDAKERRRKSCMTSCFHGGCVPHHDQECSDPRDDKRGKLFGQDLSSICQDGKLPTIILDMLSRIKDKGPTTDDIFLITPNGSLCKTIKEKLDNGENVDIYQQPVHVVAWILKEFLQSIKGSLLTSKLYDQWLIVPEKVNDKEKLAAVKSLLEKLPKPNADLLRQLFRILHQIKTKSSVNNMSSFRLSLETAPCILWLPSYRNNILTNDIAKKISLVTFMIDNSPELFGEDIVAVWYETSLYHPPGLKYPCSQNTPSSNGIMEETEHGLSSCPGERTCTPDFDELPRSGAVASIPYEGILASEKGEGNESTTQPEPVQNSPTPQTKKELGNCSPNILKDVNVPAVILDMLSVIAEKGQCSDDIFRMQAEKSHWSLKEKVNTGKHVNLKEESVLTVASVVKDFIKNIEGSLLSCDLYENWLSIPDEGPLLGKIASIQNILLKMPKPNYVLLKQLICVLQKIKAASTNQLDTFDLSVRIAPHVLWNPTCKMFYGRDLSKKLSIIQFMIDNCQELFGENDNIFCEDNQKSYDINLSSDTLNTSGKATLMIETIDDHDVKTSKANTKELEMSSAVPHEGGPTAGHNGTTSKYNVPQEIILHD", "length": 835 }, "evidence": [ { "id": "G3MZM9", "url": "https://omabrowser.org/oma/group/G3MZM9/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "A0A0G2K6V9-1", "protein_name": "non-specific serine/threonine protein kinase", "gene_name": "Smokwl2", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MDITSIKKTLGSQYRVVFFLGQGSYGRVRLAWHRRTQALVAIKTVEISKDTIRGILSEMTTLESLNHPNIISLYEVLITGTGVHFILQYAPGGNLGKLISEEGPLPEEKAKKMFGQVVSAIRYCHSLDIVHRDIKPQNILIDGEGNIKLIDFGQAIKCKPGTLLSRHCGTRDFNAPELVLREPYDGKSSDVWSLGVVLYFFTTGYLPFRGKTINDVEERITTGTYTIPTHLSGQLENLIHQILRVSPDMRPSVEEIENHPWIKKCEFKILPKTDPDYKIIEMLCAMGYKAKDILESLQKKRYDEPMGAYLSLKDHVSKGFDVGYITPAKPGDPCPPPPPSPAHPSVFGLPLRRRASEPIFGLHHRPPSREQNPLDLILSGLKMSRCVSMPPIAVYYPKKERSTSTRALHSTPVACPCVSNNMSEVEIILPPKQDIEMNTSSPPQRMGWFKRLRKGIRDCFSRLCCLPRAPKKKTQHRSSKRVAPLKKAASSTI", "length": 493 }, "evidence": [ { "id": "G3MZM9", "url": "https://omabrowser.org/oma/group/G3MZM9/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "A0A0G2K894-1", "protein_name": "Olfactory receptor", "gene_name": "Or4x6", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MAHLLNVTEFIFLGLSPNKEGQRVCFVLFLLLYMAIVLGNLLMVVTVAASRNLGSPMYFFLSFLSFVEICYSSTTAPKLIFDLLAEKKSISVWGCMTQLFFMHFFGGTEIFLLTMMAYDRYVAICKPLHYTSIMNQQVCAVLVGSAWIGGFVHSFSQILLILPLSFCGPNVIDHYFCDLLPVLKLACSDTFLIGLLIVVNGGTLSVISFVVLLASYLVILFHLRTQSAEGRRKALSTCGSHVTVVILFFGPCVFIYSRPSDTLPVDKMIAVFYTVITPLLNPLIYSLRNAEVKKAMKNLWFRIMKADEK", "length": 309 }, "evidence": [ { "id": "G3MZM9", "url": "https://omabrowser.org/oma/group/G3MZM9/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "A0A0G2KB39-1", "protein_name": "Myb/SANT DNA binding domain containing 5 like 1", "gene_name": "Msantd5l1", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MQREANQGESLENTEESNVGKSVKEEEQRPSGRSRSSWTDSEIRVFLQEWEVVEQEMGQPGRKLHKKTKSLCQRLYQQGLKKSWKSCFHLLLSLQDLHRTLCNERPGIEPLFSPYSEALYRILGSTPHESWFPGPLYDEADDSMLPVYPQPPMYQPSDYGITVPSAQLQGNPVPMMCQEDSPFPTWEPWNPSYPLSVPHLLPGFAPGDPSLQQPWSMCDLHQDPQ", "length": 225 }, "evidence": [ { "id": "G3MZM9", "url": "https://omabrowser.org/oma/group/G3MZM9/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "A0A0G2KBC9-1", "protein_name": "Leukocyte immunoglobulin-like receptor subfamily B member 3-like", "gene_name": "Lilrb3l", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MTFTFTALLCLGLTLRLWIPVLTGSLPKPILRVQPDSVVSMGTKVTFVCEETIGVKESHLYRNGNLQRTVLKNHQKPTNKTEFSFSNVDQQMQQYQCSYRTQTKSSDYSEPLELVVTGAYSKPSLSAQTNPVVTSGGYVTLKCEPSQDNHTLILTVEGSQKHSWRKDPECNRYTEKCHALFYVGPLTSNQRWIFRCYSYEKHTPQVWSAPSEPVELLVSGKLQKTTIKAEPGSVIRSGRAMTIWCQGDLDAEIYFLHKEGSHNTQSTQTLQQPGNKAKFLIPSVTQRHAGQYRCYCYSSAGWSEPSDTLELVVTGIYYYGVKLSGLPSPVVPEGGNVTLHCTSHSNYDKFILTKEDQKFTSSLDAEYIPSTGQHQALFVMGPMTPNYSGTFRCYGYYKHTPQLWSVPSELLKIFISGPSRKPSLLSHQGHILEPGMSLTLQCYSDTKYDKFALYKEGGTDIIESFSQWTKAGLSMTNFTLSVMPNSTVHSGENVTLMCWSTYSVDTFILSKEGSGQPPLRLKSKIQDQQYQSEFSMSGVTSKLSGTYRCYGSHDSSLYLKALIGVSVAFLLFLFILIFILLRRRHQEKFRKDDEDAQKGKELQLSTGAAEPVTRDRGHQKRSNPAAATQEESLYASVEDMETKDGVELDTWKPPEGDPQGETYAQVEPSRLRRAGAISPVVSREQLNTKYEQAEEGQEVDSQATESEEPQDVTYAQLCSRTLRQGTAAPPLSQAGEAPEEPSVYAALATARPGAVPKNKKQ", "length": 761 }, "evidence": [ { "id": "G3MZM9", "url": "https://omabrowser.org/oma/group/G3MZM9/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "A0A0G2KIH5-1", "protein_name": "Major histocompatibility complex class I LLA precursor", "gene_name": "mhc1lla", "tax_id": 7955, "organism": "Danio rerio", "sequence": { "sequence": "MTGKVLFVLFLLSAPTTVLTDSHSLWLLGTYIKGETQFPKLSFTVMLDDLRVGFYNSETKEFIPRDNTTNEDEAVSDVLTVIQNTLEPFMMSTLTFKNGTESPQLFQITWHCELLDNDKPGQIIFKIAFSGSTTDEVSFYNDNFTCQCQNNMATVPLESFQMHYETVCYPNCIATIRDYLKKRQTQVNGKVQPKVRLIKKVHPKSGGFRLSCLATEFYPHSINLTLLRDGQPVSDHEVTGGNLLPNGDGTYQMRKSLEIRADEREKHKYTCSVSHLSLDKILDIDFEFDPSFLIKIVIPVVVLLSLMLVLTAVLIHKCKNKRAESKETITTASTPEPTEMSETLRK", "length": 346 }, "evidence": [ { "id": "G3MZM9", "url": "https://omabrowser.org/oma/group/G3MZM9/", "database": "OMA" } ], "glygen_name": "Zebrafish", "common_name": "Zebrafish" }, { "uniprot_canonical_ac": "A0A0R4IEQ0-1", "protein_name": "Guanine nucleotide-binding protein subunit alpha", "gene_name": "gna11a", "tax_id": 7955, "organism": "Danio rerio", "sequence": { "sequence": "MTLESMMACCMSEEAKESKRINAEIDKQLRRDKRDARRELKLLLLGESGKSTFIKQMRIIHGTGYTDEDKRGYTKLVYQNIFTSMQAMIRATEHLKIPFRFEDNKKNALLVREVDVEKVCSFEQPYVAAINKLWMDPGIQEAYDRRREYQLSDSTKYYLNDLERISSRGYMPTQQDVLRVRVPTTGIIEYPFDLENIIFSYLSDLERISDPSYLPTQQDVLRVRIPTTGIIEYPFDLQSIIFRMVDVGGQRSERRKWIHCFENVTSIMFLVALSEYDQVLVESDNENRMEESKALFRTIITYPWFQNSSVILFLNKKDLLEEKILCSHLVDYFPEFDGPQNDAQSAREFILKMFVDLNPDSDKIIYSHFTCATDTENIRFVFAAVKDTILQHNLKEYNLV", "length": 400 }, "evidence": [ { "id": "G3MZM9", "url": "https://omabrowser.org/oma/group/G3MZM9/", "database": "OMA" } ], "glygen_name": "Zebrafish", "common_name": "Zebrafish" }, { "uniprot_canonical_ac": "A0A0R4ILG2-1", "protein_name": "FXYD domain-containing ion transport regulator", "gene_name": "fxyd2", "tax_id": 7955, "organism": "Danio rerio", "sequence": { "sequence": "MGVESPEHSDADFTYDYELIRRGGLIFAAVLFCLGMVIIFSKKLRCGKSSATHEDNGDL", "length": 59 }, "evidence": [ { "id": "G3MZM9", "url": "https://omabrowser.org/oma/group/G3MZM9/", "database": "OMA" } ], "glygen_name": "Zebrafish", "common_name": "Zebrafish" }, { "uniprot_canonical_ac": "A0A0R4IU63-1", "protein_name": "Metabotropic glutamate receptor 5", "gene_name": "grm1b", "tax_id": 7955, "organism": "Danio rerio", "sequence": { "sequence": "MRMLILRMNFFIVFLLFCTRLHLSTERSAVSRAASRSVARMDGDIIIGALFSVHHQPSAEKVAERKCGEIREQYGIQRVEAMFYTLDRINSDPYLLPNITLGCEIRDSCWHSSVALEQSIEFIRDSLISIRDEREGPKWCVEGNPSAQPPATKKPIAGVIGPGSSSVAIQVQNLLQLFNIPQIAYSATSIDLSDKTLYKYFLRVVPSDTLQARALLDIVKRYNWTYVSAVHTEGNYGESGMEAFKELASQEGLCIAHSDKIYSNAGEKHFDRLLRKLRERLPKARVVVCFCEGMTVRGLLMAMRRLGVAGEFLLIGSDGWADRDEVVEGYEEEAVGGITVKLQTEEVTSFNDYFLKLRLATNNRNPWFAEFWQHRFQCRLAGHPQENTNYRKNCSGYESLEDNYVQDSKMGFVINAIYAMAHGLHDMHEHLCPGHVGLCEEMDPIDGSKLLDFLLKTSFAGVSGEDVWFDENGDSPGRYDIMNLQYVEPGVFDYINVGSWHEGILSIDDYMIQMNRSEMVRSVCSEPCSKGEIKVIRKGEVSCCWICTPCKDNEYVQDEFTCKACELGWWPDEELQVCEPLPLRYLEWSHPESIAAVVFSCLGILVTSFVTLVFILYRDTPVVKSSSRELCYIILAGIFLGYICPFTLIARPSIASCYLQRLLVGLSASMCYSALVTKTNRIARILAGSKKKICTRKPRFMSAWAQVVIAFILISMQLTLEVTLIILEPPEPIKSYPSIREVFLICNTSNMGMVAPLGYNGLLILSCTYYAFKTRNVPANFNEAKYIAFTMYTTCIIWLAFVPIYFGSNYKIITTSFSVSLSVTVALGCMFTPKMYIIIAKPERNVRSAFTTSDVVRMHVGDGKIACRSNSLLNMFKRKKNASGNANSNGKSVSWSEPGSRHPPKGEHMWHRLSVHVKKQEAGSNQTAIIKPLTNTYNNPGMEFSDLSTKTLYNVAEEDEIDPIRYNPSNSPHLMAPVSKPMKEVGANLTFYTPEQHVPQQNSVLPQHAMIEHFQDDVVKYNSNMADLDEIISLPEPTDGIILALQPQVLHPHPILPMNVYQDEPSSPLEEVENEQFGLLHGYMYDNAQIHDEEELVQIKMAMEDSMALMPPSPFRDSLGSGSPVRNSPVSESVLCTPPSVTYASVILRDYKQSSSTL", "length": 1158 }, "evidence": [ { "id": "G3MZM9", "url": "https://omabrowser.org/oma/group/G3MZM9/", "database": "OMA" } ], "glygen_name": "Zebrafish", "common_name": "Zebrafish" }, { "uniprot_canonical_ac": "A0A0R4IUN8-1", "protein_name": "Trypsin inhibitor ClTI-1-like precursor", "gene_name": "spink2.9", "tax_id": 7955, "organism": "Danio rerio", "sequence": { "sequence": "MLAQIVLLLCLSVMATAADKCPSVPNCSRYHPHACTMEYWPVCGSDGNTYGNECELCATIFEEKLNIILISKKGEC", "length": 76 }, "evidence": [ { "id": "G3MZM9", "url": "https://omabrowser.org/oma/group/G3MZM9/", "database": "OMA" } ], "glygen_name": "Zebrafish", "common_name": "Zebrafish" }, { "uniprot_canonical_ac": "A0A0R4J2B9-1", "protein_name": "BTB domain containing 35, family member 23", "gene_name": "Btbd35f23", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MGLLVSRVLRCRDSSLLEPQPEGIAGASYIPVSRKRKRNSLEELATSSNVHGPQNQGMYPHQVLNYIYWKRVKISSNDAYQNLFLDGHDSDIKIRALGRTWCLHKVFLCQSGYFTNILKGTWRESHHGVINLIIKNEDIDTRSLHFVFGALYTDADLSITPLEVPQVLAAACLLRVDRVIQKCEGIMKETINRNTVCSYYLAAETYRLKAVKTRCFEWLLCNLMVHPSVALYKEVDLKLMYLLALSSDLLVMQKEIDVYTTLKIWMFLYLNPCWNGTMKQLLQHANNWLSTHMAYVDNISFLESEEGLIFQPVFKKLRFQHIICNLTSTTILEQDRLIPMAWLSPIYKQQWLTLLRTQEYGVIGPQVINEQELEECTMRCGTMIPKDGRYTWKWSVGRLGFPLRVTFTRQCVILRQRCQRCDGSACHNHIRNVIFRITLVCFDSNKRVTFRKTTGYKILTFEYNQEQIVMKLDSDVLTFPMCIFCNFLFVNLGNAENK", "length": 498 }, "evidence": [ { "id": "G3MZM9", "url": "https://omabrowser.org/oma/group/G3MZM9/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "A0A140T8Q5-1", "protein_name": "BTB domain containing 35, family member 21", "gene_name": "Btbd35f21", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MGLLVSRVLRCRDSSLLEPQPEAIAGASYIPGSRKRKRNSLEELATSSNVHGPQNQGMYPHQVLNYIYWKRVKISSNDAYQNLFLDGHDSDIKIRALGRTWCLHKVFLCQSGYFANILKGTWRESHHGVINLIIKNEDIDTRSLHFVFGALYTDADLSITPLEVPQVLAAACLLRVDRVIQQCEGIMKETINRNTVCSYYLAAETYRLKAVKTRCFEWLLCNLMVHPSVALYKEVDMKLMYLLALSSDLLVMQKEIDVYTTLKIWMILYLNPCWNGTMKQLLQHANNWLSTHMAYIDNISFLESEEGLIFQPVFKKLRFQHIICDLTSTTILEQDRLIPMAWLSPIYKQQWLTLLRTQEYGVIGPQVINEQELEECTMRCGTMIPKDGRYTWKWSVGRLGFPLRVTFTRQCVILRQRCQRCDGSACHNHIRNVIFRITLVCFDSNKRVTFRKTTGYKILTFEYNEEQIVMKLDSDVLTFPMCIFCNFLFVNLGNAENK", "length": 498 }, "evidence": [ { "id": "G3MZM9", "url": "https://omabrowser.org/oma/group/G3MZM9/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "A0A1B0GQX3-1", "protein_name": "Cortexin domain containing 2", "gene_name": "Ctxnd2", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MCVLMEDSSMSNGIDVDKGFAIAFVVLVFVFLIVMVFRCVKLVKNPYEVSSTTADLPLN", "length": 59 }, "evidence": [ { "id": "G3MZM9", "url": "https://omabrowser.org/oma/group/G3MZM9/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "A0A1B0GRH6-1", "protein_name": "Zinc finger and SCAN domain containing 4, pseudogene 3", "gene_name": "Zscan4-ps3", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MASQQAPAKDLQTNNLEFTPTDSSGVQWAEDISNSPSAQLNFSPSNNGCWATQELQSLWKMFNSWLQPEKQTKEQMISQLVLEQFLLTGHCKDKYALTEKWKASGSDMRRFMESLTDECLKPPVMVHVSMQGQEALFSENMPLKEVIKLLKQQQYATRPTPDNEQMPVDTTQDRLLATGQENSENECNNSCNATEANVGESCSGNEMDSLLIIQKEQHPEHEEGNVVRQFPHGARRASQGTPSHHVDIQSPPTTADVTMEEQPKDLSRENISEDKNNCYNTSRNAATQVYSGDNIPRNKSDSLFINKRIYHPEPEVGDIPYGFPQDSTRASQGTSTCLQESLGECFSEKDPREVPGLQSRQEQLISDPVLLGKNHEANLPCKSHQKRFCRDAKLYKCEECSRMFKHARSLSSHQKTHLNKKSELLCVTCQKMFKRVSDRRTHEIIHMPEKPFKCSTCEKSFSHKTNLKSHEMIHTGEMPYVCSLCSRRFRQSSTYHRHLRNYHRSD", "length": 506 }, "evidence": [ { "id": "G3MZM9", "url": "https://omabrowser.org/oma/group/G3MZM9/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "A0A1B0GS00-1", "protein_name": "Predicted gene, 36210", "gene_name": "Gm36210", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MHPGSPAAPGVSEPGPRELCAFVSGASAHMLRALQPRRIRPSKRRPNHRRFLHNQICREFAKIEAATQHLALTILSQKAPAQRPPFRRPPPPPPSPFLGVACAEAPMEAPHGSPSLSPVALDTSTLDLFDDILLTPTPRPLVTPDSFCQTLPAGNPQVASDVISHALGPGDQGQPTPIQAPRFSNLLLPPQKAQGGSLEPAALGCGWVDSWEAPYACDPQGVLDSWGAL", "length": 229 }, "evidence": [ { "id": "G3MZM9", "url": "https://omabrowser.org/oma/group/G3MZM9/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "A0A1B0GSB3-1", "protein_name": "Family with sequence similarity 236, member D", "gene_name": "Fam236d", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MIVMHLVGHPQLTGTEGVATEGVATAHTMLTSRGPRDTREPAPPTRSWRSRFQRALARVSKFFRRGRRTARG", "length": 72 }, "evidence": [ { "id": "G3MZM9", "url": "https://omabrowser.org/oma/group/G3MZM9/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "A0A1B0GSI2-1", "protein_name": "Family with sequence similarity 236, member C", "gene_name": "Fam236c", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MIVMHLVGHPQLTGTEGVATAHTKENSSRGPRETREPAPCTRSWRSRFQRAVARVSKFFRRRRRST", "length": 66 }, "evidence": [ { "id": "G3MZM9", "url": "https://omabrowser.org/oma/group/G3MZM9/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "A0A1C7CYU6-1", "protein_name": "Zinc finger and SCAN domain containing 4, pseudogene 2", "gene_name": "Zscan4-ps2", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MASQQAPAKDLQTNNLEFTPTDSSGVQWAEDISNSPSAQLNFSPSNNGCWATQELQSLWKMFNSWLQPEKQTKEQMISQLVLEQFLLTGHCKDKYALTEKWKASGSDMRRFMESLTDECLKPPVMVHVSMQGQEALFSENMPLKEVIKLLKQQQYATRPTPDNEQMPVDTTQDRLLATGQENSENECNNSCNATEGNVGESCSGNEMDSLLIIQKEQHPEHEEGNVVCQFPHGARRASQGTPSHHVDFPSVPTTADVPMEEQPKDLSRENISEDKNNCYNTSRNAATQVYSGDNIPRNKSDSLFINKRIYHPEPEVGDIPYGVPQDSTRASQGTSTCLQESLGECFSEKDPREVPGLQSRQEQLISDPVLLGKNHEANLPCESHQKRFCRDAKLYKCEECSRMFKHARSLSSHQRTHLNKKSELLCVTCQKMFKRVSDRRTHEIIHMPEKPFKCSTCEKSFSHKTNLKSHEMIHTGEMPYVCSLCSRRFRQSSTYHRHLRNYHRSD", "length": 506 }, "evidence": [ { "id": "G3MZM9", "url": "https://omabrowser.org/oma/group/G3MZM9/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "A0A1C7CYV3-1", "protein_name": "Zinc finger and SCAN domain containing 4, pseudogene 1", "gene_name": "Zscan4-ps1", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MASQQAPAKDLQTNNLEFTPTDSSGVQWAEDISNSPSAQLNFSPSNNGCWAIQELQSLWKMFNSWLQPEKQTKEQMISQLVLEQFLLTGHCKDKYTLTEKWKASGSDMRRFMESLTDECLKPPVMVHVSMQGQEALFSENMPLKEVIKLLKQQQSATRPTPDNEQMPVDTTQDRLLATGQENSENECNTSCNATEGNVGERCGGNEMDSLLIIQKEQHPEHEEGNVVCRFPHGARRASQGNSSHHVDFRSALTPADVPMEEQPKDLSRENISEDKNNCYNTSRNAATQVYSSDNIPRKKTDSLSINKRIYHPEPEVGDIPYGVPHDSTRASQGTSTCLQESLGECFSEKDPREVPGLESRQEEPISDPVLLGKNHEANLPCESHHKRFRRDAKLYKCEECSRMFKHARSLSSHQRTHLNKKSELLCFTCQKMFKRVSDRRTHEIIHMPEKPFKCSTCEKSFSHKTNLKSHEMIHTGEMPYVCSLCSRRFRQSSTYHRHLRNYHRSD", "length": 506 }, "evidence": [ { "id": "G3MZM9", "url": "https://omabrowser.org/oma/group/G3MZM9/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "A0A1D5P3Y4-1", "protein_name": "Large ribosomal subunit protein uL24m", "gene_name": "MRPL24", "tax_id": 9031, "organism": "Gallus gallus", "sequence": { "sequence": "MRLSALLRLAAPPKLPKGYRHGTWRPGTAAERLRNPPGQRRKKIFVEPISREDWKVFRGDTVQVLTGKDAGKQGMVTQVVRARNWVVVEGLNTHYRYVNRDAKYSSTYIASEAPLLLNQISLVDPEDRKPTEVDWRYTEEGERVRVSLRTGRIIPLPLWQRRDGIVPEQWIDGPKDTSVDDALDKTYTPSLKTFEEEIMDAMGIVETRRAKKSYWY", "length": 216 }, "evidence": [ { "id": "G3MZM9", "url": "https://omabrowser.org/oma/group/G3MZM9/", "database": "OMA" } ], "glygen_name": "Chicken", "common_name": "Chicken" }, { "uniprot_canonical_ac": "A0A1D5PNZ8-1", "protein_name": "ODF3A protein", "gene_name": "LOC124417034", "tax_id": 9031, "organism": "Gallus gallus", "sequence": { "sequence": "MPASMDGAWVGTWRPHRPRGLISAQFPSPGPQYSIPGTTGYVGHSPTKARAPAYTFRGTKPPAAGSCGPGPCYFVEPAITRNGKYVAPGAQLRGRPATKTTVTPGPSDYRTEAANRHVFKCPPVQSMAFRREPLRTDHPPGPGTYTLPRLMGPNTVYTSASPCYSVRGRSQRGRFDEDLAKTPGPAALPKVPVDAYKTRAPAYTMAARPKAGEGKAAKPGPADYSVGRVTLIKPQAPASTFGIRHSLYTTPLIVE", "length": 255 }, "evidence": [ { "id": "G3MZM9", "url": "https://omabrowser.org/oma/group/G3MZM9/", "database": "OMA" } ], "glygen_name": "Chicken", "common_name": "Chicken" }, { "uniprot_canonical_ac": "A0A1D5RLF0-1", "protein_name": "F-box and WD-40 domain protein 27", "gene_name": "Fbxw27", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "METHLPSLPLMKIFSYLDAYSLLQVAQVNKNWNALASSDVLWRKLCQKRWLFCDMVTLQLQDKETWKQFFVYRTWQEHSKTRANPRDFTYKEIPLQYGPCGYACYISGCGITRKGQDKSVVCMVNSKNTISTWDVHKSVITWVSPEQPASIKLLTTLPEMHIAVTVDIQSTIKLWDCHNREALATNILESPCKSLKAVITKDDPIVLVSDILGNLYIFRIPDLHLISTVNVLPCDIDEIYCSPQKKWVLLSKKQPYILPKVFYMSSLLRTSEFSAPVSTLLEISLCQEAFWTPRREDRLTLMSRSGCSKITKFETYDMKLEEFGNKIIVKGNSIAGFLLPYYTESLNWFGVSDKDTIVCSTEFSLLLFTNNGHRLQTFQYFSETIVRLSVDPVHVIVTCNDGSLDVYAWEERSLLLRKCYRLKNRRHLSPRGFINKTLCDDVSIIQLMIDGHDTWFLMAYALNICS", "length": 466 }, "evidence": [ { "id": "G3MZM9", "url": "https://omabrowser.org/oma/group/G3MZM9/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "A0A1P8ASP4-1", "protein_name": "Serine/threonine-protein kinase PRP4 homolog", "gene_name": "PRP4KB", "tax_id": 3702, "organism": "Arabidopsis thaliana", "sequence": { "sequence": "MVSDKHVESNHRKHRRSFSPSDEVFKSPKRHKSRHHHRRHGHRHHRDEEVQYNDDENVNGGDLDMEEGEILGKEGIGETLKKKLESVDEFGDIKSGQFRENNLAFNGDDGFPLICKSWIRVYNYLSYKCHGRNQRRERECEKRKEIEPDRERRKERGSVDRDSRGDREKDYLRDRDNDRGRSRDKARYSSRERGRENERERRSEKDRDKGREFQSDREKHKSLDDGYGEVRHKHSGHSRHDAEDDLELRSPTSVNGHDPNSGDVKETRGNVERTRIDNDDKGDVVVWEVEQEDEELNLIEESRRRTQAIMEKYKKKLEQQNGFSSHDLELANIPKQSSTVADVLGSGTLGPVTSAVNQAKAGLDIDAVDGEVAKLSSAVGESPAQLVISDSDRTLASTGLGEGSPKDKISDDMFTDDIFGESPADSQKMVCTLTQIIDLVFIEFSNSGFICFVFPVHHLTRYSRNGLPFVHYIFVGYLRGKGNGIPIVRSGLDDNWDDAEGYYSYQLGELLDDRYEIMATHGKGVFSTVVRAKDTKAELGEPEEVAIKIIRNNETMHKAGQTEIQILKKLAGSDPENKRHCVRFLSTFKYRNHLCLVFESLHLNLREIVKKYGRNIGIQLSGVRVYATQLFISLKHLKNCGVLHCDIKPDNMLVNEGRNTLKLCDFGSAMFAGTNEVTPYLVSRFYRAPEIILGLPYDHPLDIWSVGCCLYELFSGKIMFPGSTNNEMLRLHMELKGAFPKKMLRKGAFIDQHFDKDLCFYATEEDSVTRKTTKRMMVNIKPKEFGSVIKQRYKDEDSKLLVHFRDLLDRIFILDPQKRITVSQALAHPFITGK", "length": 834 }, "evidence": [ { "id": "G3MZM9", "url": "https://omabrowser.org/oma/group/G3MZM9/", "database": "OMA" } ], "glygen_name": "Arabidopsis", "common_name": "Mouse-ear cress" }, { "uniprot_canonical_ac": "A0A1P8BFV1-1", "protein_name": "Bax inhibitor-1 family protein", "gene_name": "", "tax_id": 3702, "organism": "Arabidopsis thaliana", "sequence": { "sequence": "MDGLKDFSRISPAIQSHLMRVYFSLFCILAASAFGAYLHMRLNIGGTITKLGWVLSLLEHVVSCPPYKHKIRFSLLLLFGVLHGASVGPCIKSTIDIDSSILITAFLGTAVIFFCFSAVAMLARRREYIYLGGLLSSGFSLLTWLKNSDQFASATVEIQMYLGLLLFVGCIVVNTQEIIEKAHCGDMDYAVHSLILYIGFVRVFLQILSIMWNTSADRIRRNNEET", "length": 226 }, "evidence": [ { "id": "G3MZM9", "url": "https://omabrowser.org/oma/group/G3MZM9/", "database": "OMA" } ], "glygen_name": "Arabidopsis", "common_name": "Mouse-ear cress" }, { "uniprot_canonical_ac": "A0A1W2P6Q8-1", "protein_name": "Cell division cycle 5-like protein", "gene_name": "Cdc5lrt6", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MPRIMIKGGVWRNTEDEILKAAVMKYGKNQWSRIASLLHRKSAKQCKARWYEWLDPSIKKTEWSREEEEKLLHLAKLMPTQWRTIAPIIGRTAAQCLEHYEFLLDRTAQRDNEEETTDDPRKLKPGEIDPNPETKPARPDPIDMDEDELEMLSEARARLANTQGKKAKRKAREKQLEEARRLAALQKRRELRAAGIEIQKKRKRKRGVDYNAEIPFEKKPALGFYDTSEENYQALDADFRKLRQQDLDGELRSEKEGRDRKTDKQRLKRKKESDLPSAILQTSGVSELTKKRSKLVLPAPQISDAELQEVVKVGQASEVARQTAEESGITNSASSTLLSEYNVTNNSIALRTPRTPAPQDRILQEAQNLMALTNVDTPLKGGLNTPLHESDFSGVTPQRQVVQTPNTVLSTPLRTPSNGAEGLTPRSGTTPKPVTNATPGRTPLRDKLNINPEDGMADYSDPSYVKQMERESREHLRLGFLGLPAPKNDFEIVLPENAEKELEEREIDDTYIEDAADVDARKQAIRDAERVKEVKRMHKAVQKDLPRPSEVNETILRPFNVEPPLTDLQKSEELIKKEMITMLHYDLLHHPYEPSGNKKGKNVGLATNDSEHITYLEHSPYEKFSKEDLKKAQGALVQEMEVVKQGMSHGELSSEAYNQVWEECYSQVLSLIAQSRYTRANLASKKDRIESLEKRLEINRGHMTTEAKRAAKMEKKMKILLGGYQSRAMGLMKQLNDLWDQIEQAHLELRTFEELKKREDSAIPRRLECLKEDVQLQQEREKELQQRYADLLMEKETLQAKF", "length": 802 }, "evidence": [ { "id": "G3MZM9", "url": "https://omabrowser.org/oma/group/G3MZM9/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "A0A1W2P7S8-1", "protein_name": "Cell division cycle 5-like protein", "gene_name": "Cdc5lrt1", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MPRIMIKGGVWRNTEDEILKAAVMKYGKNQWSRIASLLHRKSAKQCKARWYEWLDPSIKKTEWSREEEEKLLHLAKLMPTQWRTIAPIIGRTAAQCLEHYEFLLDKTAQRDNEEETTDDPRKLKPGEIDPNPETKPARPDPIDMDEDELEMLSEARARLANTQGKKAKRKAREKQLEEARRLAALQKRRELRAAGIEIQKKRKRKRGVDYNAEIPFEKKPALGFYDTSEENYQALDADFRKMRQQDLDGELRSEKEGRDRKTDKQRLKRKKESDLPSAILQTSGVSEFTKKRSKLVLPAPQISDAELQEVVKVGQASEVARQTAEESGITNSASSTLLSEYNVTNNSIALRTPRTPAPQDRILQEAQNLMALTNVDTPLIGGLNTPLHESDFSGVTPQQQVVQTPNTVLSTPLRTPSNGAEGLTPRSGTTPKPVTNATPGRTPLRDKLHINPEDGMADHSDPSYVKQMERESREHLRLGFLGLPAPKNDFEIVLPENAEKELEEREIDDTYIEDAADVDARKQATRDAERVKEMKRMHKAVQKDLPRPSEVNETILRPFDVEPPLTDLQKSEELIKKEMITMLHYDLLHHPYEPSGNKKGKNVGFATNDSEHITYLEHSPYEKFSKEDLKKAQDALVQEMEVVKQGMSHGELSSEAYNQVWEECYSQVLYLPAQSCYTRANLASKKDRIESLEKRLEINRGHMTTEAKRAAKMEKKMKILLGGYQSRAMGLMKQLNDLWDQIEQAHLELRTFEELKKHEDSAIPRRLECLEEDVQRQQEREKELQQRYADLLMEKETLQAKF", "length": 802 }, "evidence": [ { "id": "G3MZM9", "url": "https://omabrowser.org/oma/group/G3MZM9/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "A0A1W2P7Z8-1", "protein_name": "Cell division cycle 5-like protein", "gene_name": "Cdc5lrt7", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MPRIMIKGGVWRNTEDEILKAAVMKYGKNQWSRIASLLHRKSAKQCKARWYEWLDPSIKKTEWSREEEEKLLHLAKLMPTQWRTIAPIIGRTAAQCLEHYEFLLDRTAQRDNEEETTDDPRKLKPGEIDPNPETKPARPDPIDMDEDELEMLSEARARLANTQGKKAKRKAREKQLEEARRLAALQKRRELRAAGIEIQKKRKRKRGVDYNAEIPFEKKPALGFYDTSEENYQALDADFRKLRQQDLDGELRSEKEGRDRKTDKQRLKRKKESDLPSAILQTSGVSELTKKRSKLVLPAPQISDAELQEVVKVGQASEVARQTAEESGITNSASSTLLSEYNVTNNSIALRTPRTPAPQDRILQEAQNLMALTNVDTPLKGGLNTPLHESDFSGVTPQRQVVQTPNTVLSTPFRTPSNGAEGLTPRSGTTPKPVTNATPGRTPLRDKLNINPEDGMADYSDPSYVKQMERESREHLRLGFLGLPAPKNDFEIVLPENAEKELEEREIDDTYIEDAADVDARKQAIRDAERVKEVKRMHKAVQKDLPRPSEVNETILRPFNVEPPLTDLQKSEELIKKEMITMLHYDLLHHPYEPSGNKKGKNVGLATNDSEHITYLEHSPYEKFSKEDLKKAQGALVQEMEVVKQGMSHGELSSEAYNQVWEECYSQVLSLIAQSRYTRANLASKKDRIESLEKRLEINRGHMTTEAKRAAKMEKKMKILLGGYQSRAMGLMKQLNDLWDQIEQAHLELRTFEELKKREDSAIPRRLECLKEDVQLQQEREKELQQRYADLLMEKETLQAKF", "length": 802 }, "evidence": [ { "id": "G3MZM9", "url": "https://omabrowser.org/oma/group/G3MZM9/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "A0A1W2P855-1", "protein_name": "Cell division cycle 5-like protein", "gene_name": "Cdc5lrt8", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MPRIMIKGGVWRNTEDEILKAAIMKYRKNQWSRIASLLHRKSAKQCKARWYEWLDPSIKKTEWSREEEEKLLHLAKLMPTQWRTIAPIIGRTAAQCLEHYEFLLDRTAQRDNEEETTDDPRKLKPGEIDPNPETKPARPDPIDMDEDELEMLSEARARLANTQGKKAKRKAREKQLEEARRLAALQKRRELRAAGIEIQKKRKRKRGVDYNAEIPFEKKPALGFYDTSEENYQALDADFRKLRQQDLDGELRSEKEGRDRKTDKQRLKRKKESDLPSAILQTSGVSELTKKRSKLVLPAPQISDAELQEVVKVGQASEVARQTAEESGITNSASSTLLSEYNVTNNSIALRTPRTPAPQDRILQEAQNLMALTNVDTPLKGGLNTPLHESDFSGVTPQRQVVQTPNTVLSTPLRTPSNGAEGLTPRSGTTPKPVTNATPGRTPLRDKLNINPEDGMADYSDPSYVKQMERESREHLRLGFLGLPAPKNDFEIVLPENAEKELEEREIDDTYIEDAADVDARKQAIRDAERVKEVKRMHKAVQKDLPRPSEVNETILRPFNVEPPLTDLQKSEELIKKEMITMLHYDLLHHPYEPSGNKKGKNVGLATNDSEHITYLEHSPYEKFSKEDLKKAQGALVQEMEVVKQGMSHGELSSEAYNQVWEECYSQVLSLIAQSRYTRANLASKKDRIESLEKRLEINRGHMTTEAKRAAKMEKKMKILLGGYQSRAMGLMKQLNDLWDQIEQAHLELRTFEELKKREDSAIPRRLECLKEDVQLQQEREKELQQRYADLLMEKETLQAKF", "length": 802 }, "evidence": [ { "id": "G3MZM9", "url": "https://omabrowser.org/oma/group/G3MZM9/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "A0A1W2PP81-1", "protein_name": "TATA-box-binding protein-associated factor 11-like protein 5", "gene_name": "TAF11L5", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "METGRQTGVSAEMLAMPRGLKGSKKDGIPEDLDGNLEAPRDQEGELRSEDVMDLTEGDSEASASAPPAAKRRKTHTKGKKESKPTVDAEEAQRMTTLLSAMSEEQLSRYEVCRRSAFPRARVAGLMRAITGSSVSENAAIAMAGIAKLFVGEVVEEALDVCEMWGETPPLQPKHLREAVRRLKPKGLFPNSNCKRIMF", "length": 198 }, "evidence": [ { "id": "G3MZM9", "url": "https://omabrowser.org/oma/group/G3MZM9/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "A0A1Y7VLT7-1", "protein_name": "Eukaryotic translation initiation factor 4C", "gene_name": "Eif1ad4", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MPKNKGKGGKNRRRGKNENESEKRELVFKEYGQEYAQVTKMLGCGWLEAMCFDGVRRLCHIRGKLRKKVWINTSDIILIGLRDYQDNKADVILKYNQDEARSLKAYGELPEHAKINEMDTFGPGDDDEIVFDDIGEDDEDIDDI", "length": 144 }, "evidence": [ { "id": "G3MZM9", "url": "https://omabrowser.org/oma/group/G3MZM9/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "A0A1Y7VNG9-1", "protein_name": "Eukaryotic translation initiation factor 4C", "gene_name": "Eif1ad18", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MPKNKGKGGKNRHRGKNENESEKRELVFKEYGQEYAQVTKMLGCLWLEAMCFDGVKRLCHIRGKLRKKVWISTSDIILIGLRDYQDNKADVILKYNPDEARSLKAYGELPEHAKINETDTFGPGDDDEIVFDDIGDDDEDIDDI", "length": 144 }, "evidence": [ { "id": "G3MZM9", "url": "https://omabrowser.org/oma/group/G3MZM9/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "A0A286YCH8-1", "protein_name": "Predicted gene, 47985", "gene_name": "Gm47985", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MALGAELSETLVEKPEHMNLEMSILAPSKRKQLLDKKAEDKQPPESRGNNGRSSKSSPMGKDNTWPSPEAKVPSQKRSGQSWAVSSCGPHKRSSKLEDKRRNRPSRFRERGRDKPGSTHKRDSSHTKLHVKDRRSQPRSPVRTLKRSRSGDRQGAPHNSAKRHRQTSPPEASSLPTFSLLMSRVFTNVDALQVSLDDLQAPGGAFLRVPSSSTEPIVLQRAWLTWQLSHAGAALHWALHTVKSILTSQASLPRYTWPQGYSFTADPRPVPTSKIQASQLAQRPGDLASPNPSVDTRSILG", "length": 300 }, "evidence": [ { "id": "G3MZM9", "url": "https://omabrowser.org/oma/group/G3MZM9/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "A0A286YD13-1", "protein_name": "Predicted gene 8947", "gene_name": "Gm8947", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MALGAELSETLVEKPEHMNLEMSILAPSKREQLLDKKAEDKQPPESRCNNGRSSKSSPMGKENTWPSREAKVPSQKRSGQSWAVSSCGPHKRSSKLEDKRRNRPSRFRERGRDKPGSTHKRDSSHTKLHVKDQRSQPRSPVRTLKRSRSGDRQGAPHNYAKRRRQTFPPEASCSLPTFSLLMSRVFTNVDALQVSLDDLQAPGGAFLRVPSSSTEPSVSQRAWLTWQLSHAGAALHWALHTVNSILTAQASLPRYIWPQGYSFTADPRPVPTSKIQASQLAQRPGDLASPNPSVDTRSILG", "length": 301 }, "evidence": [ { "id": "G3MZM9", "url": "https://omabrowser.org/oma/group/G3MZM9/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "A0A286YE43-1", "protein_name": "Predicted gene, 47996", "gene_name": "Gm47996", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MALGAELSETLVEKPEHMNLEMSILAPSKRKQLLDKKAEDKQPPESRGNNGRSSKSSPMGKDNTWPSPEAKVPSQKRSGQSWAVSSCGPHKRSSKLEDKRRNRPSRFRERGRDKPGSTHKRDSSHTKLHVKDRRSQPRSPVRTLKRSRSGDRQGVPHNSAKRCRQTSPPEASSLPTFSLLMSRVFTNVDALQVSLDDLQAPGGAFLRVPSSSTEPSVSQRAWLTWQLSHAGAALHWALHTVNSILTAQASLPRYTWPQGYSFTADPRPVPTSKIQASQLAQRPGDLASPNPSVDTRSILG", "length": 300 }, "evidence": [ { "id": "G3MZM9", "url": "https://omabrowser.org/oma/group/G3MZM9/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "A0A286ZIN6-1", "protein_name": "G-protein coupled receptors family 1 profile domain-containing protein", "gene_name": "LOC110258935", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MANLTSMSGFLLMGFSDDHKLQILHALLFLVIYLLALTGHLLIITITTLDHHLHSPMYYFLKHLSLLDLCFISVTVPQSIANSLMNNGYISLGQCILQVFFFIALASSEVAILTVMSYDRYVATCQPLQYETIMDPWACRQAVIAVWVTGGLSGLTHTAINLSVPLCGDRVIHQFFCDVPQMLKLACSYEFINEIAVAAFTTSTAFFCLISILLSYTRIFSAVLRIPSAQGRTKVFSTCLPHLLVVTFFLSAAGFEFLRPPSDSQSAMDFMFSIFYTVVPLTLNPVIYSLRNKAMKAALRKVLSKEEFAQRKKYFKALFQL", "length": 321 }, "evidence": [ { "id": "G3MZM9", "url": "https://omabrowser.org/oma/group/G3MZM9/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "A0A286ZIP8-1", "protein_name": "Olfactory receptor", "gene_name": "LOC110259124", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "QEYKANGGDNTTTIIHFVLLGFSDFPHIRPALFVVFLVIYILTLTWNLCLIVLIRLDSHLHTPMYFFLSNLSFIDICYVSSTAPKMLYDFFQAKPTITVVGCAIQYFVCSTMGLSECCLMTVMAYDRYAAICNPLLYSSIMSPSLCGRMVLGSYMAGLSATLSQVCAVLQLHFCGPNVIHHFFCDMPLMLGLSCSDTFFVQVLTAIFTVFFGIINALVIMMSYVYIVISVMKITSAKGRSKAFNTCASHLTAVTLFYTSGIFVYLSSSSGGSSGLDRFAAVFYTVVIPMLNPLIYSLRNKDIKDALKRLKKRKECC", "length": 316 }, "evidence": [ { "id": "G3MZM9", "url": "https://omabrowser.org/oma/group/G3MZM9/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "A0A286ZLI4-1", "protein_name": "C-C motif chemokine ligand 24", "gene_name": "CCL24", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MFSPSSLIKASGQLQCPAGNRLLAPTLSSCIAALSPELPLLLSRHGRPVTVAASLLFLGLCAYSFAPADSVTMPSSCCIYFISKKIPESRVASYQLSNSSVCPQAGVIFTTRKGQKFCGDPKQLWVQKYMKKLDAKRKKASTRIRAMGTGAPVRRGPANSTSI", "length": 163 }, "evidence": [ { "id": "G3MZM9", "url": "https://omabrowser.org/oma/group/G3MZM9/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "A0A286ZSE3-1", "protein_name": "Olfactory receptor", "gene_name": "LOC110258059", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MRNRTITTFILLGLTDDPKLQVLIFIFLFVAYMLSLTGNLTIITLTFVDSHLKTPMYFFLKNFSFLEISFISSCIPRYLYSIATGDKVITYNACVIQVCFTDLCGVTEFFLLAAMSYDRYVAICKPLHYVTIMSSRVCGILISSCWMAGLCVLIPPLSLGLNLKFCDSNRLDHFGCDAFPLVKISCSDTWPMEQTVIICAVLTLNMTLTCVVLSYAYIIKTIFRFPSVQQRKKAFSTCSSHMIVVSITYGTCIFIYMNPTAKGEVTIKKVVSLLIFSVSPTLNPFIYTLRNNQVKRAFKDSIKRIALLSTR", "length": 311 }, "evidence": [ { "id": "G3MZM9", "url": "https://omabrowser.org/oma/group/G3MZM9/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "A0A286ZU87-1", "protein_name": "G-protein coupled receptors family 1 profile domain-containing protein", "gene_name": "LOC100152920", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MEGENQTVLFEFIILGFSNLKELQFLLFTIFLVTYICTLGGNSFIILETMTNLHLHTPMYFFLENLAFLDICYTTTNVPQMMAHLLSEKKSISYLGCMAQLFAFIFFVGSESLLLAAMAYDHYIAICKPLRYSVIMNKVLYSQLAASCWSGGFLNSTVHTVLTFRLPFCGNNQINYFFCDIPPLLVLSCGDTSVNELALLSIGVVIGWTPFLCIVLSYLYIISTILRIRSSKGRQKAFSTCASHLTIVLLYYGSAIFTYGRPISTYSLEKDRLISVLYSIVTPMLNPIIYSWRNKDIQEAMQVMGRKWKASSSLSFDV", "length": 318 }, "evidence": [ { "id": "G3MZM9", "url": "https://omabrowser.org/oma/group/G3MZM9/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "A0A286ZVC9-1", "protein_name": "Olfactory receptor", "gene_name": "LOC110258401", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MGQRNSTSLHDFILLGFSDHPKLEMALSGVVATFYLITLVGNTAIILASLLDSHLHTPMYFFLRNLSFLDLCFTTSIVPQMLVNLWGPHKTISYGGCVIQLYVYMWLGSIECLLLAVMSYDRFTAICKPLHYLVIMNPHLCLKMIIMVWSISLANSVVLCTLTLNLPRCGNNLLDHFLCELPAMLKIACIDTTAVELSVFALGIAIVLTPLILILISYGYIAKAVLRMKSRAGQRKAINTCGSHLTVVSIFYGAIIYMYLQPGNNASRGQVIFLTLFYTIITPSLNPLIYTLRNKDMKEALKKLMRVDHKSTKSKRTWKS", "length": 320 }, "evidence": [ { "id": "G3MZM9", "url": "https://omabrowser.org/oma/group/G3MZM9/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "A0A286ZWC4-1", "protein_name": "Zinc finger protein 16", "gene_name": "ZNF16", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MLPLSQVPAMPSLRTRPGKAEMEPSVPGPSLRTPGTQVSVSDAPAVTHPGSALHGPLSCGDTEPGATPPHHQLADWDLRTEGSQLLQKEDASEDLESQAGTSEDYVGAGSQAPERGELCADVLGSDWGVPQGERLSLCQEGGFMPAYLLPGSPLEEPEIDTEPLERNFGLIITPVASPGEPEEETPQPFDACDQSVHCGVDLAGHEGLHAAESSFICGECGESVGLHSDLLRHRLSHRGEKPHVCAECGEAFSQSASLESHQRSHEPAKPFQCSTCGKAFGRSSSLIKHHKVHTRERPHACGECGRPFSRFSNLVKHRRVHTGEKPYRCSECGKAFSQSSSLLQHRRVHTGEKPHVCPVCGKAFSYSSVLRKHQIIHTGVKPYSCSACGKAFSHSSALIQHQGVHSGDKPYECRECGKTFGRSSNLILHQRVHTGEKPYECAECGKTFSQSSTLIQHQRIHNGLKPHECDQCGKAFNRSSNLIHHQKVHTGEKPYTCVECGKGFSQSSHLIQHQIIHTGERPYKCGECGKAFSQRSVLTQHQRVHTGEKPYDCEACGKAFSQRSKLVKHQLIHARE", "length": 576 }, "evidence": [ { "id": "G3MZM9", "url": "https://omabrowser.org/oma/group/G3MZM9/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "A0A286ZX75-1", "protein_name": "Olfactory receptor", "gene_name": "LOC100156955", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "IFIMEWENQTASSDFILMGIFSHTPTHIFLFSLVLGIFTVALLANTVMVLLICLDRRLHTPMYFLLSQLSLMDLMLICTTVPKMARNYLSGRKSISVAGCETQIFFSVSLFGAECFLLAVMAYDRYAAICYPLQYPQLMNWNVCGLLAASSWILGVFDGIVDIAATLSFSYCGSREIPQFFCDITALLRLSCTDTSTFETLVFICCVVMLLFPLSLIIISYTRVIITVIRMSSGEGRHKAFTTCSSHLVVVGMYYGAAMFIYMRPTSNRSPAQDKMVSAFYTILTPMLNPLIYSLRNKDVAKAFSRCWGREI", "length": 312 }, "evidence": [ { "id": "G3MZM9", "url": "https://omabrowser.org/oma/group/G3MZM9/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "A0A286ZY56-1", "protein_name": "Olfactory receptor", "gene_name": "LOC110258501", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "METDNDTQILEFLLLGFSKQPESQPIIFGLFCSMYLITVFGNLLIILAVISDYHLHIPMYFFLSKLSFVDICFTSTTIPKMLWNIQTQSKAITYEGCITQIYFLILFAVLDILLLTVMAYDRFVAICHPLHYTVIMNPRLCGLLVLVPWIMSVLNSLLQTLMMMQLSFCTNFEIPHFFCELNQMIQLACSDTFLNTIVMYFAAALLCGGPFFGILCSYSKIVSSIYRISSAQGKYKAFSTCASHLSVVSLFYCTMLGVYLSSAAAHSSHSSATASVMYTVITPMLNPFIYSLRNKDMKRALKALFVKGPM", "length": 310 }, "evidence": [ { "id": "G3MZM9", "url": "https://omabrowser.org/oma/group/G3MZM9/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "A0A286ZZP6-1", "protein_name": "HSF-type DNA-binding domain-containing protein", "gene_name": "", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MANAPSEIQGVSPKDESTGSESSITSPWCDNSITGDLDLRSQIEEKAFQALSEGSLMKEPCHTLCASEPDGDNDFPPLPFPRKLWEIVESDRFKSIWWDENGTSIVINEERFKKEVLERKAPFRIFETESMKSLVRQLNLYGFTKLRRNFQRPASLANILAEDNEVSAWNKLQFYHNPNFKRGCPHLLVRMKRRVRVKNASPVSASVLQGCSKKRSRTGGDVDNHNSDVAAETRGEDAFSASTNLNVPLIRWPSMSQRISNTTTPTRSGLSSPSSPSFRPPGQIAMAQHAIFSQLTTFHMHSQSSYSPASGHIVNFITTTTSISQYRCISYFPSGYFGLRVEPSPLPTRYQNISPTEGPVSNPQPAAHPWFPMPMATDTSAASLSRPNPQSSSVSEHLPNYH", "length": 402 }, "evidence": [ { "id": "G3MZM9", "url": "https://omabrowser.org/oma/group/G3MZM9/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "A0A287A7E2-1", "protein_name": "Olfactory receptor", "gene_name": "LOC110258743", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MGQRNSTSLHDFILLGFSDHPKLEMALSGVVATFYLITLVGNTAIILASLLDSHLHTPMYFFLRNLSFPDLCFTTSIVPQMLVNLWGPHKTISYGGCVIQLYVYMWLGSIECLLLAVMSYDRFTAICKPLHYLVIMNPHLCLKMIIMVWSISLANSVVLCTLTLNLPRCGNNLLDHFLCELPAMLKVACIDTTAVELSVFALGIAIVLTPLILILISYGYIAKAVLRMKSRAGQRKAINTCGSHLTVVSIFYGAIIYMYLQPGNNASRGQVIFLTLFYTIITPSLNPLIYTLRNKDMKEALKKLMRVDHKSTKSKRTWKS", "length": 320 }, "evidence": [ { "id": "G3MZM9", "url": "https://omabrowser.org/oma/group/G3MZM9/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "A0A287A7J9-1", "protein_name": "Olfactory receptor", "gene_name": "LOC110258750", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MEQNNGTEVKEFILLGFAGQHKSWLVLFIVFLGIYVVTLVGNIGMILLIKIEASLHTPMYFFLQNLAFVDLCYATAITPKVLQNLMSTEKSISFIGCMVQLFVYGTFVTSDGYILAAMAVDRYVAICNPLRYPTVMSQRVCIQLLIGSCFMGFLNACVNGSLTFQLNFCKSNKINHFFCDAPPILALSCSSIYFNIMLLAAFVGFNLMFTVSIIIFSYIFILAAILKISSAAGRKKAFSTCGSHLTAVTIFHGTLSYMYLHHRTLESQEQEKLASVFYGIVIPMLNPLIYSLRNQDVREALKEIGKKML", "length": 309 }, "evidence": [ { "id": "G3MZM9", "url": "https://omabrowser.org/oma/group/G3MZM9/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "A0A287A951-1", "protein_name": "Small ribosomal subunit protein uS8", "gene_name": "LOC100514137", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MVHMNVLTDALESINNSEKRGKRQVLTRLCFKVIVRFLTVMMKHGTPIGKFEIMDDPRARKIVVNLTGRLNKCGVISPRFDGQLKDLEKWQNKLLPSCQFGFIVLTTSAGIMHHEEAR", "length": 118 }, "evidence": [ { "id": "G3MZM9", "url": "https://omabrowser.org/oma/group/G3MZM9/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "A0A287ACV2-1", "protein_name": "HSF-type DNA-binding domain-containing protein", "gene_name": "", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MAHAPSEIQGVSPKDAPTGSESSITSPWCDNSITGDLDLRSQIEEKAFQALSEGSLIKEPCHTLCASEPDGDNDFPPLPFPRKLWEIVESDRFKSIWWDENGTSIVINEERFKKEVLERKAPFRIFETESMKSLVRQLNLYGFTKLRRNFQRPASLANILAEDNEDSAWNKLQFYHNPNFKRGCPNLLVRMKRRVRVKNASPVSASLLQGCSKKRSRTGGDVDNHNSDVAAETRGEDAFSTSTNLNVPLIRWPSMSQRISNTTTPTRSGLSSPSSPSVRPPGQIVMAQHAIFSQLTTFHMHSQSSYSPASGHIVNFITTTTSISQYHRISNFPSGYFGLRVEPSPLPTRYQNISPTEGPVSNPQPAAHPWFPMPMATDTSVASLSRPNPQSSSISEHHPNYY", "length": 402 }, "evidence": [ { "id": "G3MZM9", "url": "https://omabrowser.org/oma/group/G3MZM9/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "A0A287AEV7-1", "protein_name": "Uncharacterized protein", "gene_name": "WFDC10AL", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MKWWGLQWLMLSCLAILPASGNWQERISASLEALTQSKLIPGMKPCKTIPTKEQCTYFCDLPRACPTGLLCCSASCGNVCMPPKGHGNRRSSHKISNFLFTAEPIKQQ", "length": 108 }, "evidence": [ { "id": "G3MZM9", "url": "https://omabrowser.org/oma/group/G3MZM9/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "A0A287AF12-1", "protein_name": "Large ribosomal subunit protein eL21", "gene_name": "", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MTNTKGKRRGTRSMSSSPFRKHGVVPLATYMRIYKKGDIVDIKGMGTAQKGMPHKCYHGKTGRVYNVTQHAVGTVVNKQVKGTILAKRINVHIVHIKHSKRGDNFLKRVKENDQKKKEAKEKVTWVQLKHQTAPAREAHFVRTNGKEPELLEPNP", "length": 155 }, "evidence": [ { "id": "G3MZM9", "url": "https://omabrowser.org/oma/group/G3MZM9/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "A0A287AGK9-1", "protein_name": "DM domain-containing protein", "gene_name": "", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MDPDEMPTVPCCPLDSTTGLETGAPWGIEFGPRRAIRRCARCHNHGITDQIKDQEHLCLFQACECHKCVLFSEHCSILPAESALKTMQELHLKRQLTQGLIKSGTTSPKAHSHVKKSSIQTGVLSKLPRCSADRSGIGIFVSVLDSSTLEEATNNFTFQEVTQAPCPAQQAPKTSDQDSDSASLEWQRKLEAAEALLTLRESSQAPSGPTPLLQPSAAPAPAGERGLQPPSRSLRPRPASSISLPIGHVGCISLLS", "length": 256 }, "evidence": [ { "id": "G3MZM9", "url": "https://omabrowser.org/oma/group/G3MZM9/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "A0A287AKK8-1", "protein_name": "G-protein coupled receptors family 1 profile domain-containing protein", "gene_name": "LOC100155397", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MDVRNHSIVSEFVFLGFTNSWEIQLLLFVFSFLFYSSSMMGNLVIVFTVTLDSHLHSPMYFLLANLPAIDMVFCSITAPKMIGNIFKKHKAISFCGCITQIFFTHAAGGTEMVLLIAMAFDRYVAKCRPHHYLTIINPRICLCFLVTSWIIGLIHSMAQLFFVVDLPFCDLNVLDSFYCDLPRLLRLACTDTQELQFMVTVNSGLLSMGSFVLLIISYIFILFTIWKHASGGSSKALSTLSAHITMVVLYFGPLIFFYTWPSPTSHLDKYLAIFDAFITPFLNPVIYTLRNKEMKVAMRRLFSHLVHYRNIS", "length": 312 }, "evidence": [ { "id": "G3MZM9", "url": "https://omabrowser.org/oma/group/G3MZM9/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "A0A287AP00-1", "protein_name": "Olfactory receptor", "gene_name": "LOC110258730", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "SRHDLHCSLWQDNSMSVKRFAFARFSEVTEQCFLLFTLILLMFLASLTGNALIATAIWTNPVLHTPMYFFLANLSLLEIGYTCSVIPKMLQSLVSEARGISREGCATQMFFFAFFGISECCLLAAMAFDRYMAICSPLHYATRMSRGVCDHLAMVSWGVGCMAALGQTNYIFSLDFCGPCEIDHFFCDLPPILALACGDTSHNEAAVFVAATLCISSPFLLIIASYGRILAAVLSMPSPEGRRKALSTCSSHLLVVTLFYGSASVTYLRPKASHSPGIDKLLALSYTVVTSMLNPIIYSLRNKDVKAALRRTLGKKKVLAHR", "length": 322 }, "evidence": [ { "id": "G3MZM9", "url": "https://omabrowser.org/oma/group/G3MZM9/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "A0A287ARD5-1", "protein_name": "Olfactory receptor", "gene_name": "LOC110258934", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MDGKNQTALSEFIILGFSNLNQLQFLLFTIFFLTYICTLGGNTFIILVTVVDPRLHTPMYHFLGNLAFLDICYTTTNVPQMMAHLLSEKKSISYGGCMAQLFAFIFFVGSECLLLAAMAYDRYIAICKPLRYSVIMNKVLYSQLAASCWSGGFLNSAVHTVLTFRLPFCGNNQINYFFCDIPPLLVLSCGDTSVNELALLSIGVVIGWTPFLCIVLSYLYIISTILRIRSSKGRQKAFSTCASHLTIVLFYYGSAIFTYVRPISSYSLEKDRLISVLYSVVTPMLNPIIYTLRNKDIKEAMKAVGRKWQLPLLSFDV", "length": 317 }, "evidence": [ { "id": "G3MZM9", "url": "https://omabrowser.org/oma/group/G3MZM9/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "A0A287AT12-1", "protein_name": "Olfactory receptor", "gene_name": "", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MLSFNRTGVSHTVFYLLGIPGLEDQHLWISIPFFISYVTALLGNSLLIFLILTRRSLHEPMFLFLCMLAGADLVLSTCTVPQALAIFWFRAGEISLDRCITQFFIIHCIFMSESGILLVMAFDRYVAICYPLRYTTILTHTLIGKIGVTIFLRSYCTVFPIIFLLKRLTFCRNNVLPHTGCEHIGLAKYACNDIRVNIWYGLFVIVSTLFLDILLIFVSYMLILRAVFHMPSQDARHKALSTCGSHVCIIILFYGPGILTTLAQRFGRHIPAHIHILLANVCVLAPPMLNPIIYGIKTKQIQEQVAHLFLKQK", "length": 313 }, "evidence": [ { "id": "G3MZM9", "url": "https://omabrowser.org/oma/group/G3MZM9/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "A0A287AUC4-1", "protein_name": "G-protein coupled receptors family 1 profile domain-containing protein", "gene_name": "", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MERINKSHPEEFILLGFADRPWLELPLFIILPMYFFLTNLSFLDMCYTTSIVPQMLFHLGGSEKTISYLGCAVQLYFFHTMGGTECLLLALMSFDHYVAICKPLHYTLIMNRCTCILLVATVWLSGMTYAVSEATVTLHLPLCGHNTLDHLICEIPVLIKAPCGEKGTNELTLSVVCIFMLAVPLCFILASYASIGHAVFKIKSSEGRKKAFGTCSSHLIVVFFFYGPDISMYLQPPSSISRDLPKFMALFHGVVTPTLNPFIYTLRNKDVKGAWGNLVRSVFTSK", "length": 286 }, "evidence": [ { "id": "G3MZM9", "url": "https://omabrowser.org/oma/group/G3MZM9/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "A0A287AXC2-1", "protein_name": "Olfactory receptor", "gene_name": "", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MEQNNGTEVNEFILLGFAGQHKSWLVLFIVFLGIYVVTLVGNIGMILLIKIEMLQNFVGTEQSISFIGCMVQLLIYGAFVTSDCYILAAMAVDRYVAICNPLRYPTVMSQRVCIQLLIGSYLIGFLNASVHVSFILPLNFCKSNKINHFFCDAPPILALSCSSIYFNVMLLAAFVGFNLTCTVLVVIFSYIFILAAILKISSAAGRKKAFSTCASHLTAVTLFYGTLSYMYLHHRTLESQEQEKLASVFYGIVIPMFNPLIYSLRNQDVREALKGVGKQCF", "length": 281 }, "evidence": [ { "id": "G3MZM9", "url": "https://omabrowser.org/oma/group/G3MZM9/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "A0A287AY25-1", "protein_name": "Olfactory receptor", "gene_name": "LOC100155405", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MAHTNESVVLEFVLLGLTNSWELQLFLFAIFSIVYVTSVLGNTMIIVIIASDSRLNSPMYFLLSNLSFIDICQSNFATPKMLVDFLVEHKTISFEGCMAQIFLLHSFVGSEMMLLVAMAYDRFIAICKPLHYSTIMSRRLCIIFVFISWAVGILHSVSHLAFTVDLPFCGPNEVDRFFCNLPLVIELACMDTYKVEILTLTNSGLISLGCFLALIISYTVILITVHRWSSSGSSKALSTLTAHITVVILFFGPCIYFYIWPFSRLSVDKFLSVFYTVCTPLLNPIIYSLRNEDVQSAMHKWRNHHVNSWKY", "length": 311 }, "evidence": [ { "id": "G3MZM9", "url": "https://omabrowser.org/oma/group/G3MZM9/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "A0A287B1Z6-1", "protein_name": "Short stature homeobox", "gene_name": "SHOX", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MEELTAFVSKSFDQKSKESSGGGGGGGGKKDSITYREVLESGLARSRELGGSDSNLQDITEGSGHCPVHLFKDHVDNDKDKLKEFGTGRAAEGIYDCKDKREDVKSEDEDGQTKLKQRRSRTNFTLEQLNELERLFDETHYPDAFMREELSQRLGLSEARVQVWFQNRRAKCRKQENQMHKGVILGTASHLDACRVAPYVNMGALRMPFQQVQAQLQLEGVAHAHPHLHPHLAAHAPYLMFPPPPFGLPIASLAESASAAAVVAAAAKSNSKNSSIADLRLKARKHAEALGL", "length": 292 }, "evidence": [ { "id": "G3MZM9", "url": "https://omabrowser.org/oma/group/G3MZM9/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "A0A287B9C9-1", "protein_name": "HSF-type DNA-binding domain-containing protein", "gene_name": "", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MAHAPSEIQGVSPKDESTGSESSITSPWCDNSITGDLDLRSQIEEKAFQALSEGSLMKEPCHTLCASEPDGDNDFPPLPFPRKLWEIVESDRFKSIWWDENGTSIVINEERFKKEVLERKAPFRIFETESMKSLVRQLNLYGFTKLRRNFQRPASLANILAEDNEVSAWNKLQFYHNPNFKRGCPHLLVRMKRRVRVKNASPVSASVLQGCSKKRSRTGGDVDNHNSDVAAETRGEDAFSASTNLNVPLIRWRSMSQRISNTTTPTRSGLSSPSSPSFRPPGQIAMAQHAIFSQLTTFHMHSQSSYSPASGHIVNFITTTTSISQYRCISYFPSGYFGLRVEPSPLPTRYQNISPTECPVSNPQPAAHPWFPMPMATDTSAASLSRPNPQSSSVSEHHPNYH", "length": 402 }, "evidence": [ { "id": "G3MZM9", "url": "https://omabrowser.org/oma/group/G3MZM9/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "A0A287BB76-1", "protein_name": "Olfactory receptor", "gene_name": "LOC100157512", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MAHTNESVVLEFVLLGLTNSWELQLFLFAIFSIVYVTSVLGNTMIIVIIASDSRLNSPMYFLLGNLSFIDICQSNFATPKMLVDFLVEHKTISFEGCMAQIFLLHSFVGSEMMLLVAMAYDRFIAICKPLHYSTIMSHRLCIIFVFISWAVGILHSVSHLAFTVDLPFCGPNEVDSFFCDLPLVIELACMDTYKIEILTLTNSGLISLGCFLALIISYTVILITVHRWSSSGSSKALSTLTAHITVVILFFGPCIYFYIWPFSRHSVDKFLSVFYTVCTPLLNPIIYSLRNEDVQSAMHKWRNRHVNSWKY", "length": 311 }, "evidence": [ { "id": "G3MZM9", "url": "https://omabrowser.org/oma/group/G3MZM9/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "A0A287BC21-1", "protein_name": "Olfactory receptor", "gene_name": "LOC100152520", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MDGKNQTALSEFIILGFSNLNQLQFLLFTIFFLTYICTLGGNTFIILVTVVDPRLHTPMYHFLGNLAFLDICYTTTNVPQMMAHLLSEKKSISYGGCMAQLFAFIFFVGSECLLLAAMAYDRYVAICKPLRYSVIMNKVLYSQLAASCWSGGFLNSAVHTVLAFRLPFCGNNQINYFFCDIPPLLVLSCGDTSVNELALLSIGVVIGWTPFLCIVLSYLYIISTILRIRSSKGRQKAFSTCASHLTIVLLYYGSAIFTYVRPISSYSLEKDRLISVLYSVVTPMLNPIIYTLRNKDIKEAMKAVGRKWQLPLLSFDV", "length": 317 }, "evidence": [ { "id": "G3MZM9", "url": "https://omabrowser.org/oma/group/G3MZM9/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "A0A287BF45-1", "protein_name": "Olfactory receptor", "gene_name": "LOC100513333", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MRNRTITTFILLGLTDDPELQVLIFIFLFLAYMLSLTGNLTIITLTFVDSHLKTPMYFFLKNFSFLEVSFISSCIPRYLYSIATGDKIITYNACFIQVCFTDLCGITEFFLLAAMSYDRYVAICKPLHYVTIMSSRVCGILISSCWMAGLCVLIPPLSLGLNLKFCDSNRLDHFGCDAFPLVKISCSDTWPMEQTVIICAVLTLNMTLTCVVLSYAYIIKTIFRFPSDQQRKKAFSTCSSHMIVVSITYGTCIFIYMNPTAKGEVTIKKVVSLLIFSVSPTLNPFIYTLRNNQVKRAFKDSIKRIALLSTR", "length": 311 }, "evidence": [ { "id": "G3MZM9", "url": "https://omabrowser.org/oma/group/G3MZM9/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "A0A287BGE2-1", "protein_name": "Olfactory receptor", "gene_name": "", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MENNQSWIAEFILVGFQLSEEMELFFFIIFFLLYIFNLLANGMILGLICLDPRLHSPMYYFLTHLAVTDISYASSNLPNMLENLVKHKKTIPFVSCTLQMLFYLAFASVECLILVVMSYDRYVAICHPLQYTVIMNWKLCTVLAIISWACGFFLALVQVSLFLRLPFCGPQKVNHFFCEIRSVLKVTCGETWINKIFLFADGVFILVTPISLMLVSYVRILWAILKIQSKEGRKKAFSTCSSHLCVVGFYFGIAMMVYLVPDDSHQQEEQQKILFLFYTFFNPLLNPLVYSLRNAQVKAAFHRIFQKNRTM", "length": 311 }, "evidence": [ { "id": "G3MZM9", "url": "https://omabrowser.org/oma/group/G3MZM9/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "A0A287BIM6-1", "protein_name": "Histone H2A", "gene_name": "", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MPGKRSRRKSPGRQGRTCARTTRAGLSASVSHMERLLREGPYAQCLSSSARVFLAATIEYLTARVLELAGDEAQIVGRRCITPELVAMAVHNNALLSAFFGTLAISQVAPTQE", "length": 113 }, "evidence": [ { "id": "G3MZM9", "url": "https://omabrowser.org/oma/group/G3MZM9/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "A0A287BK27-1", "protein_name": "Olfactory receptor", "gene_name": "", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MVTEFIFLGLSNSQELQTFLFVFFLVFYVGIVFGNLLIVLTVMIADFFRKCKVISFKGCLAQIFLLHFFGGSELVILIAMAFDRYVAICKPLRYTTIMSSNVCVGIVAAAWGTGFLHSVSQLAFAVNLTFCGPNEVDSFYCDLPRVIKLSCTDTYRLDIMVIANSGVLTVCSFVLLIISYTVILVTIQHLPSQKSSKALSTLTAHITVVLLFFGPCIFIYAWPFPIKSLDKFLAVFYSVVTPLLNPIIYTLRNKDMKTAMKRLRKWNMNSRIKP", "length": 274 }, "evidence": [ { "id": "G3MZM9", "url": "https://omabrowser.org/oma/group/G3MZM9/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "A0A287BKA6-1", "protein_name": "Olfactory receptor", "gene_name": "LOC110259008", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MTFNCSLWQDNSMSVKRFAFARFSEVTEQCFLLFTLILLMFLASLMGNALIATAIWTNPVLHTPMYFFLANLSLLEIGYTCSVIPKMLQSLVSEARGISREGCATQMFFFAFFGISECCLLAAMAFDRYMAICSPLHYATRMSRGVCVHLAMVSWGVGCMVGLGQTNYIFSLDFCGPCEIDHFFCDLPPILALACGDTSHNEAAVFVAATLCISSPFLLIIASYGRILAAVLSIPSPEGRRKALSTCSSHLLVVTLFYGSASVTYLRPKASHSPGIDKLLALSYTMVTSMLNPIIYSLRNKEVKVALRRTVGKKKVLAHR", "length": 320 }, "evidence": [ { "id": "G3MZM9", "url": "https://omabrowser.org/oma/group/G3MZM9/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "A0A287BKW4-1", "protein_name": "Olfactory receptor", "gene_name": "LOC110258932", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MEGENQTVLFEFIILGFSNLKELQFLLFTIFLVTYICTLGGNSFIILVTMTNLHLHTPMYFFLENLAFLDICYTTTNVPQMMAHLLSEKKSISYLGCMAQLFAFIFFVGSESLLLAAMAYDRYIAICKPLRYSVIMNKVLYSQLAASCWSGGFLNSAVHTVLAFRLPFCGNNQINYFFCDIPPLLVLSCGDTSVNELALLSIGVVIGWTPFLCIVLSYLYIISTILRIRSSKGRQKAFSTCASHLTIVLLYYGSTIFTYGRPISTYSLEKDRLISVLYSIVTPMLNPIIYSLRNKDIQEAMQVMGRKWKASSSLSFDV", "length": 318 }, "evidence": [ { "id": "G3MZM9", "url": "https://omabrowser.org/oma/group/G3MZM9/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "A0A287BLZ6-1", "protein_name": "G-protein coupled receptors family 1 profile domain-containing protein", "gene_name": "LOC110258167", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MAGGKNSTTITKFILLGFSEFPKLTAVLFSVFLRISLMTVSWNMGLIMLIRMDSHLHTPMYFFLSNLSLLDICYVSTIAPRMLSDFFKKYKFISFMGCTMQYFFSSLALTECCLLAAMAYDHYAAICNPLLYTAIMSPTLCVQMVAGSCVTGFFGSFIQLCALFQLHFCGQNVTNHFFCDLPQLLILSCSDTFFFQVMTSVLTVIFGLTSVLVIIISYGYIIATILKITSSEGRSKAFNTRASHLTAVTLFFGSGIFIYMYPNSGDSLSQNKLVSVLYTVIISMLDPLIYSLRNKEIQDSLSRWRKTIFSWCY", "length": 313 }, "evidence": [ { "id": "G3MZM9", "url": "https://omabrowser.org/oma/group/G3MZM9/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "A0A287BNL4-1", "protein_name": "G-protein coupled receptors family 1 profile domain-containing protein", "gene_name": "", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "TVLNARNVSTPKVFILLGFSDHPWLEMPLFIIVLAAYIRTLVGNISIIVVSRVDPNLDSPMYFFLSNLSFLDLCFTTTTIPQLLLNLWGPDKSISYGGCVTQFYMFHFWGATECIFLAVMSMDLQAICKPLRYPVIMHQQLCIFLVVMAWLSGLVNSLLQSSLTIQLPLCGNNKVDDFLCEVPVMIKMSCTDTTFNVAMLSIVGTFYSLVPLSLILVSYGFIVATVLRIQSSEGKKKAFNTCSSHTIAVSLFYGPVISMYVQPSAANSQDKNKLMSLFYSLVTPMLNPFIYTLRNKDMKGAMMRLLVSLYHQRRG", "length": 315 }, "evidence": [ { "id": "G3MZM9", "url": "https://omabrowser.org/oma/group/G3MZM9/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "A0A287BSD4-1", "protein_name": "Olfactory receptor", "gene_name": "LOC100525471", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MENENSTVVAEFIFVGLTQSRNIQLLVFVLILIFYLIILPGNFLIILTIRSDPGLTAPLYFFLGNLAFLDASYSFIVAPRMLVDFLSEKKVISYRGCITQLFFLHFLGGGEMLLLVVMALDRYIAICRPLHYSTVMNLRACYALLVALWLGGFVHSIIQVALILHLPFCGPNRLDNFFCDVPQVIKLACTDTFVVELLMVFNSGLMTLLCFLGLLASYAVILCRVRGSSSEGKTKAMSTCTTHIIVIFLMFGPAIFIYTRPFRAFPADKVVSLFHTVIFPLLNPVIYTLRNQEVKTSLKRLLNQQLA", "length": 307 }, "evidence": [ { "id": "G3MZM9", "url": "https://omabrowser.org/oma/group/G3MZM9/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "A0A2R8VHJ9-1", "protein_name": "Predicted gene, 36245", "gene_name": "Gm36245", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MSTKNEEQNEDQSEGVVIPHIQDHHCLAILAFCFFFPLGYLAYRSSCKTRTYIEQKEYEKAKATSRCTFAFVLSSIAGGSIIFFCLFSRLFFM", "length": 93 }, "evidence": [ { "id": "G3MZM9", "url": "https://omabrowser.org/oma/group/G3MZM9/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "A0A3L7ICH5-1", "protein_name": "Cytochrome c oxidase subunit 7A2-like, mitochondrial", "gene_name": "LOC100756118", "tax_id": 10029, "organism": "Cricetulus griseus", "sequence": { "sequence": "MYYKFSGFTHKLAGAWALESYSPQGLKPVASTEAPPIVFATPTKLTSSVTAYVYAGKNKVPELQKFFQNFFHLKRGLPDQMLYRTPMALTVGGTIYCLSALYMASQTPNK", "length": 110 }, "evidence": [ { "id": "G3MZM9", "url": "https://omabrowser.org/oma/group/G3MZM9/", "database": "OMA" } ], "glygen_name": "Hamster", "common_name": "Chinese hamster" }, { "uniprot_canonical_ac": "A0A3Q1LL21-1", "protein_name": "BTB domain-containing protein", "gene_name": "LOC112445444", "tax_id": 9913, "organism": "Bos taurus", "sequence": { "sequence": "MGPLNSRNLQCRESGTGELQQPEAQAGPSYVSGSRKRKQSTGPSLGPESEMSHNQEEDLQQVVCTRQGKKVKIKSEYAYQTLFLNGETSDIKIRALGKVWCLHKRFLCQSDYFATMFRDSGKECHKDIIDLEINDQNINVESLQFVLGSLYRNEYVLIKPLQVPRVLATACLLQVEDLIQQCDKTMKETINVKTVCSFYVAAETYGLHSVKTGCFEWLLHNLMTHPSVELYKKLSTDLMNLVISSSNLFVMQKEIDIYTTLKQWMFLRLNPGWKGTMKQLLVNANNWFSRHKEHDGSISFLETKQGIVFQPVFKNLRFQHIICDLASTKVIEQDALIPSEWLSCVYKRQWYTLLRAQQYREIGPRDITETELEEYSMRCGKRIVRDGTYAWKWSGYNFGVHLYVVFTSHFIIFKRHAFSQPYDGSICLQPQRNIAFRLTLVYFGSSGKLSFRKTTGYKILTFEKDEEQMVMKLDSVALSFPLYIFCNFLFISLENPGN", "length": 498 }, "evidence": [ { "id": "G3MZM9", "url": "https://omabrowser.org/oma/group/G3MZM9/", "database": "OMA" } ], "glygen_name": "Bovine", "common_name": "Bovine" }, { "uniprot_canonical_ac": "A0A3Q1LLV6-1", "protein_name": "Uncharacterized protein", "gene_name": "", "tax_id": 9913, "organism": "Bos taurus", "sequence": { "sequence": "MNLFIYVLLLSIWTSSCLDRNESNGSATAVTTHAEFKQTKLQELRRRLLIIIIGTLITGYMVTCTCFLHYSCDSEEAHKATKDKKEDITIKASRSSKISFTDSKSPTAGLGDPERQSVVSRIDKSSGPSSPRKVPSSAEKLVRPSSQKKPSKPSAPKKVLGSPPQEKLHRTRSPKKAHRQAHAHKLVSQVSPSYPEKAIKPTWPPSLQCRVKPTKTPLPYPKNQSFPEHSSADKLTKRQRYLKLKCPASAGRAEILSRPQPVKFCRCYKEKCLVCRAVSEPFITHVSEANKKHVPVPLFSRELKHFYKSYKKKQPKYNTLYGNMSDSDITTYNSDGESDREVIIMCNIKCKEDIYKNSPNN", "length": 361 }, "evidence": [ { "id": "G3MZM9", "url": "https://omabrowser.org/oma/group/G3MZM9/", "database": "OMA" } ], "glygen_name": "Bovine", "common_name": "Bovine" }, { "uniprot_canonical_ac": "A0A3Q1LUU6-1", "protein_name": "Guanylyl cyclase domain containing 1", "gene_name": "GUCD1", "tax_id": 9913, "organism": "Bos taurus", "sequence": { "sequence": "MTGPRCRRKQRPSGRPGPRGTRAPQHPTPDAGWTARRAAGAAGAEARGRDLPPQRKPAKPTAPGKGRPERGECPRRADRGGGDPEERAGGRPAWGPGAGRGGAWGRSRLPPLLPPGRWCWRPGKPARAGRALSSPVDARAAAGAGPGPWEPRAARVMRTEVDAEAAGPPLEPDEPTQSLSIQDQETAFLLEDSCQLKPGQPLPGRPWPSGDFVQLPVPIIQQLYHWDCGLACSRMVLRYLGQLDDAEFEQALQELRLTRSIWTIDLAYLMRRFGVRHRFCTQTLGVDKGYRSQSFYRKHFDTEETRVNQLFAQAKTCKVLVEKCRVSVQDIQAHLAQGHVAIVLVNSGVLRCDLCSSPPKYCCFTPSGPRCFCRSPDYQGHFIVLRGYSRAAGCVFYNNPAYADRMCSASISNFEEARTSYGTDEDILFVYADS", "length": 434 }, "evidence": [ { "id": "G3MZM9", "url": "https://omabrowser.org/oma/group/G3MZM9/", "database": "OMA" } ], "glygen_name": "Bovine", "common_name": "Bovine" }, { "uniprot_canonical_ac": "A0A3Q1M0W3-1", "protein_name": "IF rod domain-containing protein", "gene_name": "LOC787600", "tax_id": 9913, "organism": "Bos taurus", "sequence": { "sequence": "MTCGSACFSSRSGVRSSSSCVTTQRYAPGRTFSCVSACGPRPSRCCITAAPYRGVSCYRGLTGGFSSRSVCGGSRAGSSSRSFGYRSGGPSPPCITSVSVNQSLLKPLNLEIDPNAQRIKHQEKEQIKSLNSKFAAFIDKVCFLEQQNKLLETKWKFYQNQRCCESNLEPLFNGYIETLRREAERVEADTGRLASELNSLQEVLQGYKKKYEEEVALKTTAENEFVKIKQEVNRAYVLKGDLEANAHSLVEEVGFLKTLYEEELRVMQAHISDTSVVVKMDNSRYLNMDSIVAEIKAHYDEIASRSRAEAESWYRSKYEEIKATVIRHGETLRRTKEEINELNRLIQRLTAEIENAKSQNSKLEAAVTQAEQQGEAALNDARGKLAGLEKTLQKAKQDMACLLKEYQEVMSAKLGLDIEIATYRRLLEGEEQRLCEGISAVNVRVSSSRGGVVCGDLSATRTCGIGSYGVGACGSSCKKC", "length": 480 }, "evidence": [ { "id": "G3MZM9", "url": "https://omabrowser.org/oma/group/G3MZM9/", "database": "OMA" } ], "glygen_name": "Bovine", "common_name": "Bovine" }, { "uniprot_canonical_ac": "A0A3Q1MFB0-1", "protein_name": "Uncharacterized protein", "gene_name": "LOC112441459", "tax_id": 9913, "organism": "Bos taurus", "sequence": { "sequence": "MNLFIYVLLLSIWTSSCLDRNESNGSATAVTTRAEFKQTKLQELWRRLLIIVIGTLITGYMVTCTCLLHYSCDSEEAHKAAKDKKEDITIKASRSSKISFTDSKSPTAGLGDPERQSVVSRIDKSSGPSSPRKVPSSAEKLVRPSSQKKPSKPSAPKKVLGSPPQEKLHRTRSPKKAHRQAHAHKLVSQVSPSYPEKAIKSTWPPSLQCRVKPTKTPLPYPKNQSFPEQSSVDKLTKRQRYLKLKCPASAGRAEILSRPHPVKFCRCYKEKCLVCRAVSEPFITHVSDANKKHVPVTLFSRELKHFYKSYKKKQPIYNTLYGNMSDSDITTYNSDGESDREVIIMCNIKCKEDMFKNSQNN", "length": 361 }, "evidence": [ { "id": "G3MZM9", "url": "https://omabrowser.org/oma/group/G3MZM9/", "database": "OMA" } ], "glygen_name": "Bovine", "common_name": "Bovine" }, { "uniprot_canonical_ac": "A0A3Q1MI36-1", "protein_name": "non-specific serine/threonine protein kinase", "gene_name": "", "tax_id": 9913, "organism": "Bos taurus", "sequence": { "sequence": "MGSSSGSKAEFIVGGKYKLVRKIRSGSFGDMYLAINITNGEEVAVKLESQKARHPQLLYESKLCKILQGEVGIPHIRWYGQQKDYNVLVMDLLGPSLEDLFNFCSRRFTMKTVLMLADQMMGRIEYVHTKNFIHRDIKPDNFLMGIGRHCNKLFLIDFGLAKKYRDNRTRQHIPYREDKNLTGTARYASISAHLGIEQSRRDDMESLGYVLMYFNRTSLPWQGLKAATKKQKYEKISEKKMSTPVEVLCKGFPAEFAMYLNYCRGLRFEEAPDYMYLRHLFHILFRTLNHQYDYTSDWTMLKQKAAQQAASSSGQGQQAQTPTGF", "length": 325 }, "evidence": [ { "id": "G3MZM9", "url": "https://omabrowser.org/oma/group/G3MZM9/", "database": "OMA" } ], "glygen_name": "Bovine", "common_name": "Bovine" }, { "uniprot_canonical_ac": "A0A3Q1MQ28-1", "protein_name": "Ig-like domain-containing protein", "gene_name": "", "tax_id": 9913, "organism": "Bos taurus", "sequence": { "sequence": "KEQVLQPTTVVSLEGAVAEISCNHSVSDVYDFFWYLHFPGFAPRLLIKGLGPSQQGRYNMTYERFSSSLLILQVQTADAGVYYCALRYTEAGHP", "length": 94 }, "evidence": [ { "id": "G3MZM9", "url": "https://omabrowser.org/oma/group/G3MZM9/", "database": "OMA" } ], "glygen_name": "Bovine", "common_name": "Bovine" }, { "uniprot_canonical_ac": "A0A3Q1MT47-1", "protein_name": "Uncharacterized protein", "gene_name": "LOC112444909", "tax_id": 9913, "organism": "Bos taurus", "sequence": { "sequence": "MLGCEGGKRPLKPPKKQAKETDEEGKAFKHKQKEEQKTLEGLKGQIMGKVPLATGGIKESGKQ", "length": 63 }, "evidence": [ { "id": "G3MZM9", "url": "https://omabrowser.org/oma/group/G3MZM9/", "database": "OMA" } ], "glygen_name": "Bovine", "common_name": "Bovine" }, { "uniprot_canonical_ac": "A0A3Q1MUP8-1", "protein_name": "E3 ubiquitin-protein ligase", "gene_name": "LOC100336539", "tax_id": 9913, "organism": "Bos taurus", "sequence": { "sequence": "MSRLTERALPTGTSNGAPSSRRAPVLTGTTVSNNDLASLFECPVCFEYVLPPITQCKSGHLVCGNCRPKLTRCPTCRVPLTSIRNLAMEKVANLVLFPCKYTSSGCGKTMPPTEKADHEEHCEFRPCRCPCPGTSCGWQGSMDAVVPHLMQHYNESIITLRGEVVVFLAVNINLAGTLEWVMLQSCFGFHFLLVLEKLEIYDGHQKFFAVVQLIGTREQAENFTYQLELNGNRRRLSWEATPLSIHEGIATALINSDCLIFDSEVAELFAENGNLSIDVTISMC", "length": 284 }, "evidence": [ { "id": "G3MZM9", "url": "https://omabrowser.org/oma/group/G3MZM9/", "database": "OMA" } ], "glygen_name": "Bovine", "common_name": "Bovine" }, { "uniprot_canonical_ac": "A0A3Q2TUK0-1", "protein_name": "Uncharacterized protein", "gene_name": "LOC121109925", "tax_id": 9031, "organism": "Gallus gallus", "sequence": { "sequence": "MEQQGHGERGNWQTKVWKTVALVLVTVAVASFGVYCVGGLVEGIKTTAGVTARLVRRDGEIVSLDEELAKVQRQLHVLQWRARDITERALHEALRRTELPGFTGEAVQKIIHQVLEKLEESPFQMTNYASKTSGAAIVRSKTSPSWIGSGRVFWQSLPLVAYMRPPEVILEPDNHPGNCWPFPGSQGHVFIKLPVAVFPTAVTINHGVPAAAYHADSISSAPKDFAVYGLQEEDDEKGTLLGEFIFMPGQAPGQTFQLKNEHSAFIKYVRLQVLSNWGHPEYTCVYQFRLHGDPAPDGDARGKLSA", "length": 306 }, "evidence": [ { "id": "G3MZM9", "url": "https://omabrowser.org/oma/group/G3MZM9/", "database": "OMA" } ], "glygen_name": "Chicken", "common_name": "Chicken" }, { "uniprot_canonical_ac": "A0A3Q2UEY0-1", "protein_name": "Mab-21-like HhH/H2TH-like domain-containing protein", "gene_name": "LOC124418381", "tax_id": 9031, "organism": "Gallus gallus", "sequence": { "sequence": "MALVLVLALLVRALIVSGSDHAVMLERVQQHEKEQRNGEQSWVDMPALLFTLLHYWKIWLCTGLFVFLFWNMWRSLKRKQHEEGGQQEQQEREEQVEEVEPEEQQEQVEQEEQLERVEELERVDQVEHVEQEEREDQGEQVQQEEQVEEVEREDEEDEYFYHSALTRYIARRAWEKMQGRATKCVLVEELMRDLLQTFTFVCPNSFYPVLQPAIGVGSAFEGWSPCEEDIVYHLLVPIKAPHGHVFHPELGEEGDMLARNSRIRVELVCMCTREQQLGDVLCFLHHSQEELSQNQQPSLLQTLCTGSYLDVQKTAAWFNKQVPRIWRLTHRAHRYGLKVLPSSRSCKLQVTDTSSGEKVHVELLFGVQQGNLDIFLSSQNAEAVFTPSTTWPQSCAVAERKYFEYVARTAGPNSCHLVCLRLFAHILVGMGFSSYTIKTLLLHLLAIIPLEDWRRRHFLSRLENLLQYLQYCLNDKLLNHFLLGNATMPDEVVLPQAFQTASPLNLFQHLEQDPDAHSRALRDFKELKDRLFRLLLFGR", "length": 539 }, "evidence": [ { "id": "G3MZM9", "url": "https://omabrowser.org/oma/group/G3MZM9/", "database": "OMA" } ], "glygen_name": "Chicken", "common_name": "Chicken" }, { "uniprot_canonical_ac": "A0A494C0N9-1", "protein_name": "Protein FAM246B", "gene_name": "FAM246B", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MATPGRPWAQARSAYRASEVLRRVTGRRRDPGPQSNGPGREDARAPGRLARLLRQLRAEAASRSEVPRLLKLVERAGAGAAGAGERTGAHSRGSVCSVCGEPRGRATYPAGVLEVSERRLQEGLAAVREELGAEIEALRAELRAELDALRALLPPPPPSPPARREPRAVPRAAPRGPTLLRTLGTVSALVAASRPADDAPDGPAECGAHRAPARKNHKKMPVPPGAPQGGGD", "length": 232 }, "evidence": [ { "id": "G3MZM9", "url": "https://omabrowser.org/oma/group/G3MZM9/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "A0A494C0Z2-1", "protein_name": "Speedy protein E13", "gene_name": "SPDYE13", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MGQILGKIMMSHQPQPQEERSPQRSTSGYPLQEVVDDEVLGPSAPGVDPSPPRRSLGWKRKRECLDESDDEPEKELAPEPEETWVAETLCGLKMKAKRRRVSLVLPEYYEAFNRLLEDPVIKRLLAWDKDLRVSDKYLLAMVIAYFSRAGLPSWQYQRIHFFLALYLANDMEEDDEAPKQNIFYFLYEETRSHIPLLSELWFQLCRYMNPRARKNCSQIALFRKYRFHFFCSMRCRAWVSLEELEEIQAYDPEHWVWARDRAHLS", "length": 265 }, "evidence": [ { "id": "G3MZM9", "url": "https://omabrowser.org/oma/group/G3MZM9/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "A0A4X1TRA8-1", "protein_name": "Small ribosomal subunit protein eS19", "gene_name": "", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MPGVTVKDVNQQEVVRALAAFLRKSGKLKVPEWVDTVKLVKHKELAPYDENWFYTRAASTPRHLYLWGIAGVGSMTKTYRGHQRDRVMPSHFSRGSKSVAHRLLQAREGLKMVEKDQDGGRKLTPQGQRDLDRIAGQVAAAKKKH", "length": 145 }, "evidence": [ { "id": "G3MZM9", "url": "https://omabrowser.org/oma/group/G3MZM9/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "A0A4X1TY10-1", "protein_name": "Olfactory receptor", "gene_name": "LOC100627324", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MENYNQTSIYFILLGLFPSSRIGMFLFIIIVLIFLIALFGNFSMILLIFLDNNLHTPMYFLLSQLSLMDLTYISTIVPKMAYNFLFNDKSISFIGCGIQSFFFLTLAGAEGLLLAAMAYDRFVAICFPLHYHIRVSKRICVLMIIGSWIMGSINSFAHTAYALNIPYCQSRAINHFFCDVPAMLTLACIDTWVYESTVFVSTTIFLLVPFTCIAFSYGRILLVVHHMNSTEGKKKAYSTCSTHLTVITLYSAPFAYTYLRPKFLRTPTEDKVLAMLYTIFTPMLNPIIYSLRNKEVMGALRRVIQRICSVKM", "length": 312 }, "evidence": [ { "id": "G3MZM9", "url": "https://omabrowser.org/oma/group/G3MZM9/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "A0A4X1U699-1", "protein_name": "Olfactory receptor", "gene_name": "LOC100524234", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MRRENQSSVSMSKFVLVGLHIWPEQQGMVFALFLGMYLTTVLGNLLIILLIRLDPRLHTPMYFFLSHLAFSDVSFSSVTVPKMLMNMQTQDQSIPYAGCVTQTYFFIFFSCIDNLLLAVMAYDRYVAICHPLRYAIIMKEELCLCLLAGSWLLSCAYALTHTLLLAQLSFCADNIIPHFFCDLASLIKLSCSDTSLNELVIFSLGPAVFIFPLSGILVSYGCIVVSILSVHSPKGIFKALSTCGSHLSVVSLFYGTSMAVYLSSSSGQSHDKDTIASIMYTVVTPLLNPFIYSLRNRDMTLALQILFRNSNLLAK", "length": 315 }, "evidence": [ { "id": "G3MZM9", "url": "https://omabrowser.org/oma/group/G3MZM9/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "A0A4X1VK25-1", "protein_name": "Elongin-C", "gene_name": "", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "RSYGGCEGPDASYGKLIASDKFIVKREHVLTSGAIKAMFSSPGQFAEKETDVVNFRETPSGIPSAALWKVCMYLPHKVCYTSNTSEIPEFPINSEFPIAPDIALEPLMAANLLDC", "length": 115 }, "evidence": [ { "id": "G3MZM9", "url": "https://omabrowser.org/oma/group/G3MZM9/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "A0A571BD55-1", "protein_name": "BTB domain containing 35, family member 26", "gene_name": "Btbd35f26", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MGLLVSRVLRCRDSSLLEPQPEAIAGASYIPGSRKRKRNSLEELATSSNVHGPQNQGMYPHQVLNYIYWKRVKISSNDAYQNLFLDGHDSDIKIRALGKTWCLHKVFLCQSVYFANILKGTWRESHHGVINLIIKNEDIDTRSLHFVFGALYTDADLSITPLEVPQVLAAACLLRVDRVIQQCEGIMKETINRNTVCSYYLAAETYRLKAVKTRCFEWLLCNLMVHPSVALYKEVDLKLMYLLALSSDLLVMQKEIDVYTTLKIWMFLYLNPCWNGTMKQLLQHANNWLSTHMAYVDNISFLESEEGLIFQPVFKKLRFQHIICDLTSTTILEQDRLIPMAWLSPIYKQQWLTLLRTQEYGVIGPQVINEQELEECTMRCGTMIPKDGRYTWKWSVGRLGFPLRVTFTRQCVILRQRCQRCDGSACHNHIRNVIFRITLVCFDSNKRVTFRKTTGYKILTFEYKEEQIVMKLDSDVLTFPMCIFCNFLFVNLGNAENK", "length": 498 }, "evidence": [ { "id": "G3MZM9", "url": "https://omabrowser.org/oma/group/G3MZM9/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "A0A571BF50-1", "protein_name": "WD repeat domain 88", "gene_name": "Wdr88", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MTKDNEEILNSPDQVRKGSPDVKKKKKIKKKRVKPKGDLDSKKLDFVEDSWWKGSLKNKNLDFAEYNWVLVDNRRVSVDSRKSSADSKRGSADSKRGSADSKRGSADSKRGSADSKRGSVDSKRGSVDSKRGSVDSKRGSVDSKRGSVDSKNRFSPKKMDFSEDREISQPTFLRAQQSKVPWALMRALGLFKLSLPDIRRYYNLTSHDPLALDKDRQPREKSHMATVKKFWGNQQPLSKIPYKILIGHDHIVSSCHFCMNDTRFLSSSYDCSVKLWDAEDGTVIWDFEPRPKAPVLECSITADNRRIVASSYDKTVRAWDVETGQLLWKVRHDTFVVCCKFSPNGKFVLSALDVDRGIYLMDPENITTVIHMKDHHQRSITSCCFDPDSQKVASVSMDRCIKIWDITSRTTLFTIPKAHYNAISDCCFTSTGHFLCTSSWDKNIKIWNVHTGEFRNRGACVTLMKGHEGCVSSCCIARDSSFLISGGFDKTVAIWDVGGGYRKLALKGHEDWVTDVAISNNKKWILSASKDSSMRLWNIEEIDKIPLVSENKKAMGLKVRQVGIR", "length": 565 }, "evidence": [ { "id": "G3MZM9", "url": "https://omabrowser.org/oma/group/G3MZM9/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "A0A571BG45-1", "protein_name": "BTB domain containing 35, family member 25", "gene_name": "Btbd35f25", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MGLLVSRVLRCRDSSLLEPQPEAIAGASYIPGSRKRKRNSLEELATSSNVHGLQNQGMYPHQVLNYIYWKRVKISSNDAYQNLFLDGHDSDIKIRALGRTWCLHKVFLCQSGYFANILKGTWRESHHGVINLIIKNEDIDTRSLHFVFGALYTDADLSITPLEVPQVLAAACLLRVDRVIQQCEGIMKETINRNTVCSYYLAAETYRLKAVKTRCFEWLLCNLMVHPSVALYKEVDLKLMYLLALSSDLLVMQKEIDVYTTLKIWMFLYLNPCWNGTMKQLLQHANNWLSTHMAYVDNISFLESEEGLIFQPVFKKLRFQHIICDLTSTTILEQDRLIPMAWLSPIYKQQWLTLLRTQEYGVIGPQVINEQELEECTMRCGTMIPKDGRYTWKWSVGRLGFPLRVTFTRQCVILRQRCQRCDGSACHNHIRNVIFRITLVCFDSNKRVTFRKTTGYKILTFEYKEEQIVMKLDSDVLTFPMCIFCNFLFVNLGNAENK", "length": 498 }, "evidence": [ { "id": "G3MZM9", "url": "https://omabrowser.org/oma/group/G3MZM9/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "A0A571BG86-1", "protein_name": "BTB domain containing 35, family member 8", "gene_name": "Btbd35f8", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MGLLVSRVLSCRDSSLLEPQPEAIAGASYIPGSRKRKRNSLEELATSSNVHGPQNQGMYPHQVLNYIYWKRVKISSNDAYQNLFLDGHDSDIKIRALGRTWCLHKVFLCQSGYFANILKGTWRESRHGVINLIIKNEDIDTRSLHFVFGALYRDADLSITPLEVPQVLAAACLLRVDRVIQQCEGIMKETINRNTVCSYYLAAETYRLKAVKTRCFEWLLCNLMVHPSVALYKEVDLKLMYLLALSSDLLVMQKEIDVYTTLKIWMFLYLNPCWNGTMKQLLQHANNWLSTHMAYVDNISFLESEEGLIFQPVFKKLRFQHIICDLTSTTILEQDRLIPMAWLSPIYKQQWLTLLRTQEYGVIGPQVINEQELEECTMRCGTMIPKDGRYTWKWSVGRLGFPLRVTFTRQCVILRQRCQRCDGSACHNHIRNVIFRITLVCFDSNKRVTFRKTTGYKILTFEYKEEQIVMKLDSDVLTFPMCIFCNFLFVNLGNAENK", "length": 498 }, "evidence": [ { "id": "G3MZM9", "url": "https://omabrowser.org/oma/group/G3MZM9/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "A0A5G2QG78-1", "protein_name": "Olfactory receptor", "gene_name": "LOC100523228", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MTRGENTTNITDFVLLGFSDFPQIRAALFVVFLVIYILTLTWNLCLIVLIRMDSHLHTPMYFFLRNLSFIDICYVSSTAPKMLYDFFQAKPTITVVGCAIQYFVCSTMGLSECGLMTVMAYDRYAAICNPLLYSSTMSPSLCGRMVLGSYMAGLSASLSQVCAMLQLHFCGPNVIHHFFCDMPQLLVLSCSDTFFLQLLTLVLTVIFGILNALVIMMSYVYIVISVMKITSTKGWSKAFNTCASHLTAVTLFYTSIIFVYLSSSSGGSSGLDRFAAVFYTVVIPMLNPLIYSLRNKDIKDAWKRLKKRKECC", "length": 312 }, "evidence": [ { "id": "G3MZM9", "url": "https://omabrowser.org/oma/group/G3MZM9/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "A0A5G2QIN7-1", "protein_name": "ADAM metallopeptidase domain 7", "gene_name": "ADAM7", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MSNSHYLSALFSREFLASNYSETYYSTKGEEVTTHPQIMDHCFYQGSIIHEFDSAASISTCSGLRGFFRVNDQRYLIEPVKYSDEGEHLVFRYNPKVQHAANYSCTELNFTRTAVLKDNTKSMEDSKMESIEKEKHIELFIVADNNVYHRNPNSKVRNRVWGMVNFVNMIYKTLDIHVTLVGLETWTNGDKIEIDSNIETTLKRFSAWQEIILKKKKNFDHVVLLSGKWLYTSAQGTSYPGGMCLPYYSSSVVKDLLPDLNTIASRMAHQLGHSLGMKHDDYPCTCTLGKCVMDSGGSIPALKFSKCSRTQYQQYLKDFKPTCMFDIPFSDKLSDYPYCGNKKLDDGEECDCGPVQECTNPCCDARKCMLKPEFTCAEGECCESCQVKKAGSLCRPAKDECDFPETCTGHSPACPKDQFQVNGFPCKDAKGYCFMGNCPTRDDQCSELFDNEAKDSSDICYKMNKNGNKFGYCKNEEQTLIPCEEKDVKCGKIFCTGGKHASILGEEKVYHLKKPLTQNVTECKTFFLYHKSKDFGLVAPGTKCGEGKVCSNSECVTIEKAYNSTDCPSPCNENAVEDGDLGCQCEGVQASVDWEETLNVTNISILVVVLILVIIGVLSAVLLIRYQKCIKLKQVQRPPSEALGVENKGYTGDEQQTRTEPILPDIHPLHRRTAESLARLPTSFSSPHYITLKPASKEPRGTADPNPSAKVSLKLDIQNGCASLS", "length": 725 }, "evidence": [ { "id": "G3MZM9", "url": "https://omabrowser.org/oma/group/G3MZM9/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "A0A5G2QM02-1", "protein_name": "Olfactory receptor", "gene_name": "LOC100623139", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MTGGENTTNITAFVLLGFSDFPHIRAALFVVFLVIYILTLTWNLCLIVLIRMDSHLHIPMYFFLSNLSFIDICYVSSTAPKMLYDFFQAKPTITVVGCAIQYVVFSTMGLSECGLMTVMAYDRYAAICNPLLYSSIMSPSLCGRMVLGSYMAGLSATLSQVCAVLQLHFCGPNVIHHFFCDMPLMLGLSCSDTFFVRVLTAVFTVIFGIINALVIMMSYVYIVISIMKITSAKGWSKAFNTCASHLTAVTLFYTSGIFVNLNSSSGGSSGLDRFAAVFYTLVIPMLNPLIYSLRNKDIKDALKRLKKRKECC", "length": 312 }, "evidence": [ { "id": "G3MZM9", "url": "https://omabrowser.org/oma/group/G3MZM9/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "A0A5G2QUE5-1", "protein_name": "Olfactory receptor", "gene_name": "LOC100524011", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MRRENQSNVSKFLLLGLPIQQEQQGMFFALFLGVYLTTVLGNLLIILLIRLDPRLHTPMYFFLSHLALTDISFASVTVPKMLMNMQAQDHSISYAGCVTQTYFFMFFACIDNLLLTVMAYDRYVAICHPLRYTIIMREELCICLLAGCWLLSCAYALTHTLLLAQLSFCVDNIIPNFFCDLAALLQLSCSDTSLNELVIYTSGAAVFIFPPSGILVSYGRIGISILRVPSTKGICKALSTCGSHLSVVSLFYGTIMALYFSPSFGQSHYKGIIASVMYTVVTPMLNPFIYSLRNRDMTLALEILIRNKNLFTT", "length": 313 }, "evidence": [ { "id": "G3MZM9", "url": "https://omabrowser.org/oma/group/G3MZM9/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "A0A5G2QWK6-1", "protein_name": "Calmodulin 3", "gene_name": "CALM3", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "VSAEREEEGVALKFKEAFSLFDKDGDGTITTKELGTVMRSLGQNPTEAELQDMINEVDADGNGTIDFPEFLTMMARKMKDTDSEEEIREAFRVFDKDGNGYISAAELRHVMTNLGEKLTDEEVDEMIREADIDGDGQVNYEVTASPVLGPAREGPRASAPSWGGKQPLAIACNQPRRSSGFSWDLPSFENLLSSTLWSPASGDGRGVEHSGRPS", "length": 214 }, "evidence": [ { "id": "G3MZM9", "url": "https://omabrowser.org/oma/group/G3MZM9/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "A0A5G2R7Y6-1", "protein_name": "Olfactory receptor", "gene_name": "LOC100524140", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MGQRNQTSSLADFILEGLFDDSPAHAFLFSLTMVVFLVAVSGNTLTILLICADPRLHTPMYVLLSQLSLMDLMHVSTTIPKMAINHLSGTKSISFVGCATQYFLFLSLGGAECLLLTFMSYDRYVAICHPLRYAVLMNRKVGQMMAVMSWLGASVNSLIHTVILMHFPFCGHRNIHHFYCEFPAVVQLVCGDITVYEIAVYIGDIVLLLLPIVLISASYVFILHSVIHMHSAGGKRNAFATCSSHLTVVSLWFGACIFSYMRPRSQRTPLQDKVGSVFYTIITPTLNPLIYTLRNKDIAKALKRVLGREMITQNPKVRLP", "length": 320 }, "evidence": [ { "id": "G3MZM9", "url": "https://omabrowser.org/oma/group/G3MZM9/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "A0A5G2RGH3-1", "protein_name": "Olfactory receptor", "gene_name": "LOC100524855", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MGRRNQTSSLADFILEGLFDDSPAHAFLFSLTMVVFLIAVSGNTLTILLICADPRLHTPMYVLLSQLSLMDLMHVSTTIPKMAINYLSGTKSISFVGCATQYFLFLSLGCAECILLTFMSYDRYVAICHPLRYTVLMNRKVGQMMAVTSWLGASVNSLIHTVILMHFPFCGHRNIHHFYCEFPAVVQLVCGDITVYETAVYISDIVLLLLPIILISASYIFILHSVIRMHSAGSKRNAFATCSSHLTVVSLWFGACIFSYMRPRSQRTPLQDKVGSVFYTIITPTLNPLIYTLRNKDIAKALRRVLGREMITQNPKVRLP", "length": 320 }, "evidence": [ { "id": "G3MZM9", "url": "https://omabrowser.org/oma/group/G3MZM9/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "A0A668KLA6-1", "protein_name": "Predicted gene, 52955", "gene_name": "Gm52955", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MNSSSEHCNVSDWLRLEATVKASVYVVAFSITTSLTIVIIAIVSQSLQLRKEVRLVLLCHHLLCISSYCGLGVVFQGMGALLANSPLLLCWLVFGAQLSVGEGILLTLTLMALNTYLAICYPLNSPSFVDSAKYRILAGTWTTVILKNVGLFLIEGTSPTPASVFQSAPLCPVILNGMPARVIGMFSLAFLLSVILVSYCLIYREGKRAGHFNKSNIKARRTVLVHLLQISLHVIPTLIIIGLGKQCGVFFFALNLALFGIFAFAQCFNPLVYGLHNRDLQSKLYPSLCCQKKLLP", "length": 296 }, "evidence": [ { "id": "G3MZM9", "url": "https://omabrowser.org/oma/group/G3MZM9/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "A0A668KLA7-1", "protein_name": "Predicted gene 7582", "gene_name": "Gm7582", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MNSSSEHCNVSDWLRLEATVKASVYVVAFSITTSLTIVIIAIVSQSLQLRKEVRLVLLCHHLLCISSYCGLGVVFQGMWALLANSPLLLCWLVFGAQLSVGEGILLTLTFMALNTYLAICYPLNSPSFVDSAKYRILAGTWTTVILKNVGLFLIEGTSPTPASVFQSAPLCPVILNGMPARVIGMFSLAFLLSVILVSYCLIYREGKRAGHFNKSNIKARRTVLVHLLQISLHVIPTLIIIGLGKRCGVFFFALNLALFGIFAFAQCFNPLFYGLHNRDVQSKLYPFLCCRKKLLP", "length": 296 }, "evidence": [ { "id": "G3MZM9", "url": "https://omabrowser.org/oma/group/G3MZM9/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "A0A668KM50-1", "protein_name": "RIKEN cDNA A930007A09 gene", "gene_name": "A930007A09Rik", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MLSLSELPQKNTDLAEMQSGPLGRCSHFFWLGVAFDAVGVAVLFTGVFANLLFYDMLLYLGSIIIFVSLLWWISWYTGNIEALPEDPLRGTSPRESGVHRSGSRRFSLTLRSVSDTFQRIRRRRRRRLHPRVVQRISSISSTDPGQLERNCDARTSGGRALFRSAKPEAVLNQFSRVQTSKSLPLGIVHTGLSICTSRSQPVFSVTSQTYPLASDSNSQMAMSSDSHVYLDSHSQEHSKISVASQIYPLEREESQSHLLVIPDSLSMVPVTSQSQILPSVSSESCVPLGPHSQGRSKISVATQIYPLEREESQSHFLVIPDSLSMVPVTSQSQILPSVSSESCVPLGPHSQGRSKISVASKIYPLEREESQSHLLVIPDSLSMVPVTSQSQILPSVSSESCVPLGPHSQGRSKISVATQIYPLEREESQSHFLVIPDSLSMVPVTSQSQILPSVSSESCVPLGPHSQGRSKISVASKIYPLEREESQSHLLVIPDSLSMVPVTSQSQILPSVSSESCVPLGPHSQGRSKISVASQIYPLEQEESQSHFLVPMPSDSFPVVPMTSQSQIQGSLAQQSHLQNLPLASQTPETDKASKSHTLAKGVPGVPPGSAQTQHPQASLAQTSQISSPVRKVPKN", "length": 636 }, "evidence": [ { "id": "G3MZM9", "url": "https://omabrowser.org/oma/group/G3MZM9/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "A0A8C2LDI6-1", "protein_name": "Large ribosomal subunit protein eL33", "gene_name": "LOC100774916", "tax_id": 10029, "organism": "Cricetulus griseus", "sequence": { "sequence": "MSGRLWCKAIFAGYKRGLCKQRGHTALLKIEGVYARAETEFYLGKRYAYVYKEKNNTVTLRCKPNKARVIWGKVTKAHGNSGMVHAKFRSNLPAKVIGHRIRVVLYPSRI", "length": 110 }, "evidence": [ { "id": "G3MZM9", "url": "https://omabrowser.org/oma/group/G3MZM9/", "database": "OMA" } ], "glygen_name": "Hamster", "common_name": "Chinese hamster" }, { "uniprot_canonical_ac": "A0A8C2LMV8-1", "protein_name": "Large ribosomal subunit protein eL21", "gene_name": "LOC100755948", "tax_id": 10029, "organism": "Cricetulus griseus", "sequence": { "sequence": "MTNTEGKRRGTRYMFSRPFRKSEVVPLAMYMRIYKKGDIVDIKGMDTVQKGMPHKCYHGKTGRVYNVTKHAVGIIVNKQVKGKILAKRINVQMKHIKHSKSRDSFLKQVKENDQKKKEAKEKGTWVQLKRQPVPPREAHFVRTNGKEPQLLEPISYEFMA", "length": 160 }, "evidence": [ { "id": "G3MZM9", "url": "https://omabrowser.org/oma/group/G3MZM9/", "database": "OMA" } ], "glygen_name": "Hamster", "common_name": "Chinese hamster" }, { "uniprot_canonical_ac": "A0A8C2LSR6-1", "protein_name": "Large ribosomal subunit protein uL5", "gene_name": "LOC100751955", "tax_id": 10029, "organism": "Cricetulus griseus", "sequence": { "sequence": "MSQDEGEKENPMWELHICKLCLSICVEESRDRLTRAAKVLEQLKGETPVFSKARYTMRSFGIRSNEKIAVQCTVHGTKTEEILEKGLKVQEYELWRNNFTDTGNFGFEIQEHIDLAIKYDPSIRIHGLDFYVVLGRPGFTIADKHRTGCIGAKHRISKEEAMRWFQHKYDGIILPGK", "length": 177 }, "evidence": [ { "id": "G3MZM9", "url": "https://omabrowser.org/oma/group/G3MZM9/", "database": "OMA" } ], "glygen_name": "Hamster", "common_name": "Chinese hamster" }, { "uniprot_canonical_ac": "A0A8C2LUM6-1", "protein_name": "Tubulin alpha-1C chain-like", "gene_name": "LOC100757824", "tax_id": 10029, "organism": "Cricetulus griseus", "sequence": { "sequence": "MCECISIHVGQAGVQIGNACWELYCLEHGIQPDGQMPSDKTIGGGDDSFNTFFSETDTGKHIPRVVFVDLEPTAIDEVRTGTYRQLFHPEQLITGNEDAANNYARGHYTIGKEIIDLVLDRIRKLADQCTGLQGFLVFHSFGGGTGSRFTSLLMEWLSVDYGKKSKLEFSIYPAPQVSTAVVEPYNSILTTHTTLEHSDCAFMVDNEAIYDICRRNLDIERPTYTNLNRLISQIVSSITASLRFDGALNVDLTEFQTNLVPYPRIHFPLATYAPVISAEKAYPTPLPE", "length": 288 }, "evidence": [ { "id": "G3MZM9", "url": "https://omabrowser.org/oma/group/G3MZM9/", "database": "OMA" } ], "glygen_name": "Hamster", "common_name": "Chinese hamster" }, { "uniprot_canonical_ac": "A0A8C2LZU4-1", "protein_name": "Glia maturation factor", "gene_name": "Gmfg", "tax_id": 10029, "organism": "Cricetulus griseus", "sequence": { "sequence": "MSDSLAVCEVDPELKEKLRKFRFRKETDNAAIIMKVDKARQMVVLEEEIQNVSPEELRLELPERQPRFVIYSYKYLHDDGRVSYPLCFIFSSPVGCKPEQQMMYAGSKNRLVQTAELTKVFEIRATDDLTEAWLQEKLAFFG", "length": 142 }, "evidence": [ { "id": "G3MZM9", "url": "https://omabrowser.org/oma/group/G3MZM9/", "database": "OMA" } ], "glygen_name": "Hamster", "common_name": "Chinese hamster" }, { "uniprot_canonical_ac": "A0A8C2M625-1", "protein_name": "U3 small nucleolar RNA-associated protein 15 homolog", "gene_name": "LOC100755487", "tax_id": 10029, "organism": "Cricetulus griseus", "sequence": { "sequence": "MAGYKPVAIQTYPVLGEKITQDTLYWNNYKTPVQIKEFGAVSKVDFSPQPPYNYAVTASSRIHIYGRYSQEPIKTFSRFKDTAYCATFRQDGQLLVAGSEDGVVQLFDISGRAPLRQFEGHTKAVHTVDFTADKYHVVSGADDYTVKLWDIPNSKEIQTFREHSDYVRCGCASKLNPDLFVTGSYDHTVKMFDARTNKNVLCVEHGQPVESVLLFPSGGLLVSSGGRYVKVWDMLKGGQLLVSLKNHHKTVTCLCLSSSGQRLLSGSLDRKVKVYSTTSYKVVHSFDYAASILSLALSHEDETIVVGMTNGILSVKHRKSEAKKESLSRRRRPAYRTFVKGKIYMKQRDDIMINRPAKKHLEWYDKDLKSFRISKALDRVLEPNCVIKTPEVTVSIIKELNRRGVLANALAGRDEKEITRVLNFLIRNLSQPRFAPVLINAAEIVIDIYLPVIGQSPVVDKKFIVLQGLVEKEIDYQRELLETLGMMDMLFATMSRNDSVSLSENVPAELPEKTESPCQPGDTDKNS", "length": 527 }, "evidence": [ { "id": "G3MZM9", "url": "https://omabrowser.org/oma/group/G3MZM9/", "database": "OMA" } ], "glygen_name": "Hamster", "common_name": "Chinese hamster" }, { "uniprot_canonical_ac": "A0A8C2MXE3-1", "protein_name": "Glycerol-3-phosphate acyltransferase 1, mitochondrial", "gene_name": "Gpam", "tax_id": 10029, "organism": "Cricetulus griseus", "sequence": { "sequence": "MDESSVTLGTIDVSYLPNSSEYSLGRCKHATEDWGDCGFKTTFFRSATLKWKESLMSRKRPFVGRCCYSCTPQSWERFFNPSIPSLGLRNVIYINETHTRHRGWLARRLSYILFVQERDVHKGMFATSVTENVLNSSRVQEAIAEVAAEMNPDGSAQQQSKAIQKVKKKARKILQEMVATVSPGMIRLTGWVLLKLFNSFFWNIQIHKGQLEMVKAATETNLPLLFLPVHRSHIDYLLLTFILFCHNIKAPYIASGNNLNIPIFSTLIHKLGGFFIRRRLDETPDGRKDVLYRALLHGHVVELLRQQQFLEIFLEGTRSRSGKTSCARAGLLSVVVDTLSSNTIPDILVIPVGISYDRIIEGHYNGEQLGKPKKNESLWSVARGVIRMLRKNYGYVRVDFAQPFSLKEYLESQSQKPTSAPLSLEQALLPAILPARPNDAAESEDTSSNEPRNTADEAFRRRLIANLGEHILFTASKSCAIMSTHIVACLLLYRHRQGIHLSTLVEDFFVMKEEVLARDFDLGFSGNSEDVVMHAIQLLGNCVTITHTSRKDEFFITPSTTVPSVFELNFYSNGVLHVFIMEAIIACSLYAVLNKRGSGASAGGPGSFISQEQLVRKAASLCYLLSNEGTISLPCQTFHQVCHETVGKFIQYGVLTVAEQDDQEDVSPGLAEQHWDKKLPEPLNWRSDEEDEDSDFGEEQRDCYLKVSQSKEHQQFITFLQRLLGPLLEAYSSAAIFVHNFSGPVPETEYLQKLHRYLITRTERNVAVYAESATYCLVKNAVKMFKDIGVFKETKRKRVSVLELSGTFLPQCNRQKLLEYILSFVVL", "length": 827 }, "evidence": [ { "id": "G3MZM9", "url": "https://omabrowser.org/oma/group/G3MZM9/", "database": "OMA" } ], "glygen_name": "Hamster", "common_name": "Chinese hamster" }, { "uniprot_canonical_ac": "A0A8D1BQI2-1", "protein_name": "Uncharacterized protein", "gene_name": "LCE5A", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MSCQQNQQQCQPPPKSLPKYSTPKFPGPCPPLVSSCCGSRSGHGRCYSSGGGGCCLSHHRRRRYHPCQPQSSNCCDSGGGQQSGGSGCSHSSGGSGCCSGGCC", "length": 103 }, "evidence": [ { "id": "G3MZM9", "url": "https://omabrowser.org/oma/group/G3MZM9/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "A0A8D1VKI8-1", "protein_name": "Uncharacterized protein", "gene_name": "NCR3", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MARMLLLILIRVHSGSCALWVSQPPEICTQEGTPAFLPVPSTPARGDWPLALSHGTGTNWPQGRRVVVLGQGVRTGNGTPLVVERGPAQLATPTIFLLRAGFYAFGFLSVAIGSTIYYQGKCHRHMGTHCRSADGL", "length": 136 }, "evidence": [ { "id": "G3MZM9", "url": "https://omabrowser.org/oma/group/G3MZM9/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "A0A8I5XVN6-1", "protein_name": "SPATA31 domain-containing protein", "gene_name": "LOC689526", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MESFLLLMNSAIESWMNTSTMDIATDLSIAILCGVGLFFLLIPFLKDCPLSPASGNKTDIPKDVKRGRSNTRRKTDVEKGCRDGGKTVEETKTPSQPMKILTRQLLQDSTPQIFWNSSQKLDHLLLSQLFSSLTSLEDLILQKFNRRFWGTSSIFSESVVAMAHVLRNPSFPQQKSVRFSDPCVTDQAPSQAQGLRQQHRYHPRLHRQRKTSLVGMTWVPEKKILPISTPKQIHPCLKRRAYGVSCPTTEKGIQTSLPPECLSHKHGLYSKAVKGYVKRNHQKAIGKPPGNWLRDTLKTKAIRPASILSEHLRMFLHHKEPQTKDKATNVEKQQGTCIRSPPSKKLKQFQGRFPPNTDHYCKRRPQLSQPGQPSILNSKSYKLRKIIQSVLAGMTLMKDRADFSMQSQFSQAPQSSVCNAKRYKYSKRMGSVPRRVPLKKDTARYDMGKPIKKCLGAGTKNVPHSACSILGKRLRARNLALKKGQASVMNPTGNYCLHDSKAEMKLASNNTALPVQCRRTPYLQILEALNPIPPGVLASKLPRIVFPSSPICDFKEEYYSKAATVLKNLHHQDPGGTRVKSTSAASLESALSMCSAAKIQKTQRAPPPAASRGLSKAHTDLLKRHLSIQHSALYFEQGRIIQGTGKGSLQQNTNPQKAKHAPLKSFHEGDSRHHSWNGTMVGPGKRVPPAAAKQTKAVEVKKETPYAWSLGSNESHTGKDINISPRVFGSLGAKRSPGHLQTCTPQHSQDSTLRTQGHRNIILCSNKQPQPRPGRHDPECPSTVHPAKVNLSSEHSMSSFQNTCQKPKTAQGSCERADTKENRVLKDKIRINHLKDLCPHKERQGSIRPTAISQGGRLGRSRPCSLSSTQLKDTAKTRTSDKRQATSKSSWKSDIREVLKYGYVGSKDIIGQEDTSKKDQPPAVTERTEEDWTGEKAMCNMIAHLQYLTNFLFEIMEDTEWDPSKLQGCEVESLTFQLGSSSDSSEGDDDINQGTSTSTMSFGQTSPEMHNCSFTKTGIGDKTQSEIKAKTACDQHLNQVNRGMFSDQLPMPKEYDLSCRYRGIQHQQELGLPDQTFYQYKLRMTHCPHGGTKGHNYSFGYRKLGDQQQPDFTHKALDPHQSAKEDMGCVSCLSPKGSRPVKHRRTDCFSP", "length": 1151 }, "evidence": [ { "id": "G3MZM9", "url": "https://omabrowser.org/oma/group/G3MZM9/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "A0A8I5XWP3-1", "protein_name": "Ig-like domain-containing protein", "gene_name": "ENSRNOG00000063695", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MQRDMCHMTPYRLLCVLVALALSGCNVAQEVTQVQSTASRQEGEEVTLDCSYETSYVAYYLSWYKQHLSGDIIFLIHQISSSTAEERSGRYSLVFQKSLKSISLVISASQPEDSGKYFCALSDLTQC", "length": 127 }, "evidence": [ { "id": "G3MZM9", "url": "https://omabrowser.org/oma/group/G3MZM9/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "A0A8I5Y4M0-1", "protein_name": "Large ribosomal subunit protein uL14", "gene_name": "LOC108350588", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MSEQRRGGSSGAKFRISLGLQVGAVINRADSTGTKNVYIISVKEIKGRLDRLPAAGVGHMVMATVQKSRPQLRKKVHPAMVIRQQKSCGRKDGVSLYFEEDAEVIVNNKGKMKGSAITGPIAKEHADSWPRIASNAGSTA", "length": 140 }, "evidence": [ { "id": "G3MZM9", "url": "https://omabrowser.org/oma/group/G3MZM9/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "A0A8I5Y5C9-1", "protein_name": "Ribosomal protein L32 like 2", "gene_name": "Rpl32l2", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MAALRPLMKPKIIQKRTKKFIRHQSDRYVKIKRNWRKPRGINNRVRRRFKGQILVPNIGYGNNKKTKHMLPSCFRKFLVHNVKELEVLLMCSKSYCAEIAHNVSSKNRKAILERAAQLAIRVTNPNDRLCSKENE", "length": 135 }, "evidence": [ { "id": "G3MZM9", "url": "https://omabrowser.org/oma/group/G3MZM9/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "A0A8I5Y6V7-1", "protein_name": "UPAR/Ly6 domain-containing protein", "gene_name": "Pate4", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MRNTEPLFDIVINCPIAPQFILKILLFPYPANTNLICNTCNRSENSECKNGTGQCTAPEGGSCSTISIYHGQRHVLSKQMCLGHCEEKPHYNGDFMIYVMCCSKNLCNSF", "length": 110 }, "evidence": [ { "id": "G3MZM9", "url": "https://omabrowser.org/oma/group/G3MZM9/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "A0A8I5Y7P1-1", "protein_name": "Heterogeneous nuclear ribonucleoproteins A2/B1", "gene_name": "ENSRNOG00000069815", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MEREKEQFCKLFLGGLSFETTGESLRNYYERWGKLTDCVVMRDPASKRSRGFGFVTFSSMARPHSIDGRVVEPKRAVAREESGDPGAHVTVKKLFVVGIKEDTEVHHFRDYFEEYGKIDTTEIITDRQSGKKRGFGFVTFDDHDPVDKIVLQKYHTINGHNAEVRKALSGQEMQKAQSSRSGRGGNFGFGNSRDGGGNFGPGQGSNFRRGSGGWESSDGYGSGRGFGDGYNGYGGGTGGGNFGGSPGYGEGRGGYGGGGPGYGNQDGSYRGGYDNYGGGNYGKGNYNDFGNHNQQPSNCGPMKSGNFGGSRNMGGPRDEHRSFPSWKGYNGVFGKQSPLTWIKTHSL", "length": 347 }, "evidence": [ { "id": "G3MZM9", "url": "https://omabrowser.org/oma/group/G3MZM9/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "A0A8I5ZKP8-1", "protein_name": "Glycerol-3-phosphate dehydrogenase [NAD(+)]", "gene_name": "Gpd1l2", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MGATTLRVCIVGFWSWGSAIAKIIGTNVKNQQKFASTVKMWVSEEAVNGRKLTDIINHYHENVKYLPGHKLPENVVAVANLSEAVQDADLLVFTTPHQFIHKICNEITGRVPKKALGIIHMESIDEGPRGLMLISDIIREKIGMDVSVLMGANTAREVAAGEFCETTIGSKVIQNGILFKELLQTSNFCITVVDDADAVELCGALKHIVAMGTNFCNGLHCGNNSKAAVLRLGLVEMITFTRIFCKSQVSTTTFLESCGFANPITICYRGSDCKEAKTFPRIGKTMGNLQKEVLNGQTLQGLKTSALVYQFLKQKGLLAKFPLFVTVYRICYEGRPSTEILTCLQNHPAHM", "length": 351 }, "evidence": [ { "id": "G3MZM9", "url": "https://omabrowser.org/oma/group/G3MZM9/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "A0A8I5ZL63-1", "protein_name": "Ankyrin repeat domain 13a", "gene_name": "Ankrd13a", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MVSDQSRKAAAEGGSSPMVWSRPARAPPGGRADGRGPIVERTTGEGRAGDESRRARTVGFVRGDLGLPKGPAVPQNGGGRVSRRGGLVGRHGAGLGPFRKSGPPPRSVMERLAYFPVRGGSAGSSRFASCQRGRERAGRGVGAAERVPEPVPSPARDPGPPAPPAPDSEALVVRCARHLAARRSPPLALRPVGRAPETPSGGSRLVAGGRSGLGGDLLAMSSARDTSSRFPLHLLVWNNDYRQLEKELRDQNAEALDPRGRTLLHLAVSLGHLESARVLLRHKADVTKENGQGWTVLHEAVSTGDPEMVYTVLQHRDYHNTSMALEGVPELLHKILEAPDFYVQMKWEFTSWVPLVSRICPNDVCRIWKSGAKLRVDITLLGFENMSWIRGRRSLIFKGGDNWAELMEVNHDDRVVTTEHFDLSQEMERLTLDLMKPKSREVERRLTSPVINTSLDTKNVAFERTKSGFWGWRTDKAEVVNGYEAKVYSVNNVSVITKIRTEHLTEEEKKRYKEDRNPLESLLGTVEHQFGAQGQDLTTECATVNNPTAITPDEYFDEDFDLKDRDIGRPKELTIRTQKFKATLWMCEEFPLSLVEQVIPIIDLMARTSAHFARLRDFIKLDFPPGFPVKIEIPLFHVLNARITFGNVNGCSTAEERQSVEGTQAECAASDATNFEVDQSVFEIPESYHVQDNGRNVHLQDEDYEIMQFAIQQSLLESSRSQDLSGPASNGGVSHAHSYEAQYERAIQESLLTNMEGRCPGGLSDSSRFDSDLRLAMELSAKELAEQELRLQEEEAELQQVLQLSLTEK", "length": 809 }, "evidence": [ { "id": "G3MZM9", "url": "https://omabrowser.org/oma/group/G3MZM9/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "A0A8I5ZP24-1", "protein_name": "Large ribosomal subunit protein uL30", "gene_name": "ENSRNOG00000064315", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MEAVPEKEKKVAAVPGTLKKKKVPAVPETLKKKRRNFSELKVRRLRKKFALKTLRKARRKLICEKAKHYHKECRQMYLTEIRMARMARKAGNVYVSAEPTLAFVIRIRGISGVSPKVREVLQLLRLRQILNGTFVKLSKASVKMLRIVEPYIAWGYPNLKSVNELIYKRGYGKIRKKRIALTDNSLMARSLGKFGIICMEDLIHEIYTVGKHFKEANNFLWPLKLSSPRGGMKKKTTHFVEGGDAGNRETR", "length": 251 }, "evidence": [ { "id": "G3MZM9", "url": "https://omabrowser.org/oma/group/G3MZM9/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "A0A8I5ZPV0-1", "protein_name": "ATP synthase peripheral stalk subunit F6, mitochondrial", "gene_name": "ENSRNOG00000066253", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MIVQRIFRLSSVLPSAVSVHLRSNPGVTAVAFNKEPDPVQKLFVDKIREYKTKRQVSGGPVDTGPEYHQDLDREPFKLKQLYGKGEMDKFPTFKFEDPKFVVIDKPQS", "length": 108 }, "evidence": [ { "id": "G3MZM9", "url": "https://omabrowser.org/oma/group/G3MZM9/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "A0A8I5ZRI3-1", "protein_name": "Natural killer cell cytotoxicity receptor 3 ligand 1", "gene_name": "Ncr3lg1", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MASQSCQRGPENAHMHPKGPCCSALCFLCSLGSSPHGSSLGPLRKCGRRSKPVQSSPEGSRVAEWPDGLLSLLLLLWSLLPSAGGLELEMAGTTQIVFLHEDVTIPCKILGSLHLDLSIVGVIWSLKKDGDESEVFKFYGDQLEAVRPGANVSLLGLEHGDASLYLPRFELWEAGEYQCKVVVTPEKKEGTTRLEVVAHPNMSLSEKPATARGGKEKLIICQLDGFYPEALDIKWMGSALKDSHFQEITEGVVTGPTVKNDDGTFSVTSSLALKPALEDHMYQCVVWHRSWLMPQSLNVTVFENTRDSTHGTVPPTAEVGPPVSEPRSVMIYVTIIGLCILLFSVIVCGLWKWKRLTTSNTGLCLRLDVRC", "length": 371 }, "evidence": [ { "id": "G3MZM9", "url": "https://omabrowser.org/oma/group/G3MZM9/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "A0A8I5ZS91-1", "protein_name": "non-specific serine/threonine protein kinase", "gene_name": "LOC134482834", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MPTETEEELPTPTPKPSISEEGNFHSQYQVLGTSGQGGNGKVLLAHNRLTGTPVAVKVLRKDKQWFQPAMMEANIMRKINHPNIVSLIQVIEKETRIYLIMELVEGQELYQYIRESGHIEEDEARQIFEQILSAVSYCHGKGIVHRDLKLDNIMIDKNKKVKVIDFGLSTQFPPGKMLNHHCGTHSFGSSELLLGHRYDRPKNDMWIIGVVLYCMVVGKLTFDSVIIQDLQRQVVAGVYPAPCGVSKELEDLLSKLLRVNPNFRPTARKAMKHPWFKEHWNGLIVPYEELLPLTPDPAILDAMKSIGLQASVVKHTLKQRKYNEEMATYFFLQKQALQGDGCTAQAQQVSPVAAPFPSLDPAAAFRLEPKRSGSLPVLGTLRVSSSHGHVSHYGQNAHPKGGKRYTVAGRLRPLPMTPTQDHYHKCAVSVPCIQTTSIFSEKSSNKKIKEDNPLSHRAPLEDKPIPSRVRHRGFKGWTRNIANALIKLCCCMPRRKKPRLGQNRISPQK", "length": 509 }, "evidence": [ { "id": "G3MZM9", "url": "https://omabrowser.org/oma/group/G3MZM9/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "A0A8I5ZT61-1", "protein_name": "non-specific serine/threonine protein kinase", "gene_name": "LOC134479845", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MDITSIKKTLGSQYRVAFFLGQGSYGSVKLAWHRRTQALVAIKTVEISKNTIRAILSEMTTLELLHHPNIISLFQILVTANQIHFILQYAPGGNLVQLISEEGPLPEEKAKKMFGQIVSAIRHCHSLDIVHRDIKPQNILIDGEGNVKLIDFGLAVKCRPGTLLSRHCGTRGFNAPELVLRQPYDGKSSDVWSLGVLLYFITTGYFPFRGNTIDEIEQKITTGTYTVPHHLSGQLENLIHQIFTVSPEMRPSIEEIENHPWIKKCELKIPPMSDPDYKIIEMLCGMGYNAKDILESLQKKRYDEPMGAYLSLKNHVSEGYDLASITPTKPGDPCPPPPPSPAHPSVFGLPLRRRASEPNFGLLHRQPSREQNPLDLILSGLNMGRCVSMPPIAVYYPKKQRSTSTRALHSRPVASPCVYNNMLGVEIILPHKQDIEMNTSSPPQTMGWFKRLRKGIGDCFSRLCCFPRAPKKKTQHRSSKRVAPLKKAASSTI", "length": 493 }, "evidence": [ { "id": "G3MZM9", "url": "https://omabrowser.org/oma/group/G3MZM9/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "A0A8I5ZXB5-1", "protein_name": "Uncharacterized protein", "gene_name": "Pilrb2l2", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "TALLSSLPGRNLAMARLLLLLLSAACLHTGNSAGYQEKNDFGVDQPDVLSGVQGGSIEIPFSFYFPWKLAKDPQMSIAWRWKHYHGEFIYTSTRPFIHEHFKGRLIMNWTPGQTSGVLRILNLKENDQATYFSSVFLQTPEGMKLWQSIPGTKLIIHALDTTMRSPSIIPSVVPTDDLEYTQGQRNPSLLNLGAMVGMVMAKVVVIIPLYGWMIFLWWKQR", "length": 221 }, "evidence": [ { "id": "G3MZM9", "url": "https://omabrowser.org/oma/group/G3MZM9/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "A0A8I5ZY57-1", "protein_name": "40S ribosomal protein S26", "gene_name": "LOC134478821", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MSPGPRRPRQEAGSKPRELQQRVLASVKRRCLFSSLGSNTTKKKRNNGRAKKGHGHVQPIRCTNCARCVPKDKAIKMFVIRNILEAAAVRGISEANVFDAYVPPKLYLKLHYCVSCAIHSKVVGNRSCEARKDQTPPPRFRPSGAAPQPPPKPM", "length": 154 }, "evidence": [ { "id": "G3MZM9", "url": "https://omabrowser.org/oma/group/G3MZM9/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "A0A8I5ZYE5-1", "protein_name": "Oligosaccharyltransferase complex subunit", "gene_name": "Ostcl1", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "METKHSALLRTFPFLVLECPNLKLKKPPWVHMLLAMTMYALVVVSYFFITGGIIYDVSIEPPSVDSMTDEHGHQRPVAFLARRVNGQYIMEGLASSFLFTMGGLGFIILDRSNTPNIPKLSGFLLLFDFVCVLLSFFIARVFMRMKLPDCLMG", "length": 153 }, "evidence": [ { "id": "G3MZM9", "url": "https://omabrowser.org/oma/group/G3MZM9/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "A0A8I5ZYN2-1", "protein_name": "Non-selective voltage-gated ion channel VDAC2", "gene_name": "AABR07051831.1", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MAECCVLVCPRPMCIPPPYADLGKAARDIFNKGFGLGLVKLDVKTMSCSGGEFSISGSSNTDTGKVSGTLETKYKWCGYALTFTEKWNTNNTLGTEIAIENQICQGLKLTFDTMFSPNTGKKSGKIKSAYKRECINLGYDVDFDFDFGWLAGYQMTFDSAKSKLTRNNFAVCYRTGDFQLHTNVNNGTEFGGSIYQKVLCEDFDTSVNLAWTSGTNCTRFDIIAKYQLDPTASISAKVNNSSLIGVGYAQTLRPGVKLTPSALVYGKSFNAGGHKLGLDLELEV", "length": 284 }, "evidence": [ { "id": "G3MZM9", "url": "https://omabrowser.org/oma/group/G3MZM9/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "A0A8I5ZYX3-1", "protein_name": "Methyl-CpG binding domain protein 3 like 3", "gene_name": "Mbd3l3", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "LGELGNAGRLTGSMIPSRLQKRRKIQVAKSKRKAKHKSGTTLRNPLRLTSCIFPQPVTVITSYPENKTRYRRDEAKLKKPQQLCALERLKNFQFGGDSKENLSCPLELANAVERIARGMQDEASNQSGDKDQLTSGQVTSDQPPYLETNEHVALQLSPSFSSQGVTLPVPLHLSPSYFLRKVTTGDIQRQAWKVKKARKRLAEALEADRLARQTENMRE", "length": 219 }, "evidence": [ { "id": "G3MZM9", "url": "https://omabrowser.org/oma/group/G3MZM9/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "A0A8I5ZZU9-1", "protein_name": "Keratin-associated protein", "gene_name": "ENSRNOG00000070302", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "SPSTCELSSSLHSDCQETCIEPSICQRSCVASSPCQMPCYYPRSSTACSPCQGTYDGSMGVGSNSLKSFGGFTGSLGYGNSGFGSFGFGSCGIRSQGFGCNFHRPGYFSSKSVQSSYYQPGYTSGFC", "length": 127 }, "evidence": [ { "id": "G3MZM9", "url": "https://omabrowser.org/oma/group/G3MZM9/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "A0A8I5ZZY5-1", "protein_name": "Ribosomal protein eL8/eL30/eS12/Gadd45 domain-containing protein", "gene_name": "ENSRNOG00000064452", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MTKIKAVTEESEAQGEGCSQQHRYQELLVYLNPIAQHPGFPPPDLRKIEKGKKKKKRRPTKQKQIRHGVKEVQKFVNKGKKGIMVLTGDTLRGTAIFQLCARTRICPTSIFPLTDLGAAMGSKHPTCVIMVKLHEEYHEAYDKCLEEVQTLATPL", "length": 155 }, "evidence": [ { "id": "G3MZM9", "url": "https://omabrowser.org/oma/group/G3MZM9/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "A0A8I6A2Z7-1", "protein_name": "Developmental pluripotency associated 1, pseudogene 1", "gene_name": "Dppa1", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MMPPQVLISGLLLLLPAAWTTTVTSSDQLWNNHTEVVPTQSPLKISTKDLYIGTSVSAALLILLAGVLAVLKYRHRRKKILESAVVFHGFQNGVFQSTEQSQAVDVYVIEDSKVPVAH", "length": 118 }, "evidence": [ { "id": "G3MZM9", "url": "https://omabrowser.org/oma/group/G3MZM9/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "A0A8I6A3D9-1", "protein_name": "Small nuclear ribonucleoprotein Sm D3", "gene_name": "Snrpd3l1", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MSIGRPIEVLQEAQGYMVTRETITGEVYPGKLIEAEDNMNCQMSNITVTYRDGPVAQPEQVYICDTKIRFPILPNMLKNAPVLENLKNKNQGSRAGQGKAAILKAQVAARGRGHEMGPWKLPEAKTVFSIKENFPSCLLLGF", "length": 142 }, "evidence": [ { "id": "G3MZM9", "url": "https://omabrowser.org/oma/group/G3MZM9/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "A0A8I6A3N0-1", "protein_name": "Uncharacterized protein", "gene_name": "Pramef20-ps2", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MTVQTPPTLEKLAIQSLIRNEDVAMSSLGELPAVLFPALFKEAFTGKHINLVKEVVAAWPFPCLLVGALMKTPNLETLQAVLDGVDMQLTRKFHTRRTKLQVLDLRNMHHYFWNIQAGEEDSSCSAENSKEKKVVKVFHRYALRKRVKVIVELYIHSCLKEEQTCLLKWAQQRKGSLHFCCTKMKVWNLSLCGIGEILKVFDPQHITELELHTEWTLLELAHFAPYFGQMRNLQKAFLAPLHRIMFSNSNGKRDREAKCIKKFISQFSKFNCLQHLHMFCVHFLRDHMNQVLGCLMTPLTLSITYYLISQKDLDSLSRSQSLFQLKHLDLRGVVLCDLDIMPLRGLLEKVADTLETLDLQWCKMTDSQLYALLPALRHCCQLTMVNFYSNNFSVPILKDLMQHIANWSRIRVQQYPAPLECYDDLAQVSVKRFAKLSSELMYTLGVIRQTKNISFATDICHTCGQRCVYHNGSRLCCCWH", "length": 480 }, "evidence": [ { "id": "G3MZM9", "url": "https://omabrowser.org/oma/group/G3MZM9/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "A0A8I6A3R7-1", "protein_name": "Ubiquinol-cytochrome-c reductase complex assembly factor 3", "gene_name": "LOC120093241", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MEAARKALTVVAVLGSGAGVGSILFALVTPGELQKQLMLQEMPERDSRRRDAAVRTKELVMATLKDAAATKENVAWRRNWTVRGDGRSA", "length": 89 }, "evidence": [ { "id": "G3MZM9", "url": "https://omabrowser.org/oma/group/G3MZM9/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "A0A8I6A3T5-1", "protein_name": "Large ribosomal subunit protein mL62", "gene_name": "Mrpl58", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "EHGGRLGPTLEPEPSWNLVAPAARALCSPDSAQTGERHRVQEHLQPGQAVPRIQGRGYRLEGPGEPRKAGRKGRFLLLLDRLSISYCRSSGPGGQNVNKVNSKAEVRFHLASADWIAEPVRQKIALTHKNKINKAGELVLTSESSRYQFRNLAECLQKIRDMIAKASQVPKEPSKEDAQLQRLRIEKMNRERLRQKRINSTIKTSRRMTMD", "length": 211 }, "evidence": [ { "id": "G3MZM9", "url": "https://omabrowser.org/oma/group/G3MZM9/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "A0A8I6A478-1", "protein_name": "T-cell activation Rho GTPase-activating protein", "gene_name": "LOC134485907", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MGEIHRTLLCQGPVELTSGRKRNKRYLSLFDDVLVVSTNLTKKKFKIKCIIPLNYLWVVDDVELVRANQTCTCKTIFFYWATGNALATFRSKEQKVQWYTFLTRSINEAKKGIKKTFPLHIFPEDIQTCDSSLCVTATNMDTVNDIMEKLLPMIRVHNIEDYQLWFSPGHKETPRALQGHEYPYDIIMNNVQNNLSKSNSKIFTAFPPLPGLFMENQSWDTGGQFILKPRDSAGSQQQDAKERPRKSCMTSCFHGGSVPHHDQECSDPRDDKRGKLFGQDLSSICQDGKLPTIILDMLSRIKDKGPTTDDIFLITPNGSLCKTIKEKLDNGENVDIYQQPVHVVAWILKEFLQSIKGSLLTSKLYDQWLIVPEKVNDKEKLAAVKSLLEKLPKPNADLLRQLFRILHQIKTNSSVNNMSSFRLSLETAPCILWLPSYRNNILTNDIAKKISLVTFMIDNSPELFGEDIVAVWYETSLYHPPGLKYPCSQNTPSSNGIMEETEHGLSSCPGERTCTPDFDELPRSGAAASIPYEGILASEKGEGNESTTQPEPVQNSPTPQTKKELGNCSPNILKDVNVPAVILDMLSVIAEKGQCSDDIFRMQSEKSHWSLKEKVNTGKHVNLKEESVLTVASVVKDFIKNIEGSLLSCDLYENWLSIPDEGPLLGKIASIQNILLKMPKPNYVLLKQLICVLQKIKAASTNQLDTFDLSVRIAPHVLWNPTCKTLFGRDLSKKLSIIKFMIDNCQELFGENDNIFCEDNQKSYDINLSSDTLNTSGKATLMIETIDDHDVKTSKSNTKKLEMSSAVPHEGGPTAGHNGTTSKYNVPQEKILHD", "length": 834 }, "evidence": [ { "id": "G3MZM9", "url": "https://omabrowser.org/oma/group/G3MZM9/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "A0A8I6A4C1-1", "protein_name": "RRM domain-containing protein", "gene_name": "ENSRNOG00000063783", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "LTCCAINSDPHPDSGLKMEGHDPKEPEQLRKLFIGGLSFEATDDSLREHFEKWGTLTDCVVMRDPQTKRSRSFSFVTYSCVKEVDAAMCAQPHNVDGRVVEPKRAVSREDSVKPGAHLTVKKIFVGGIKEDTEEYNLRDYFEKYGKIKTMEVMEDRLIDKIVVQKYHTINGHNCEVKKALSKQEMQSAGSQRGRGGGSGNFMGRGGNFGRGGNFDGRGGYGGGGGGSRGSYVGGDGGYNGFGGDSGNYGGGPGYSSRGGYGGGGPGYGNQGGGYGGGGGGYDSYNEGGNFGGGNYGGGGNYNDFGNYSGQQQSNYGRMKRGRFGGRSSGSPYGGGYGSGGGSGGYGSRKF", "length": 350 }, "evidence": [ { "id": "G3MZM9", "url": "https://omabrowser.org/oma/group/G3MZM9/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "A0A8I6A5E5-1", "protein_name": "Paired immunoglobulin-like type 2 receptor alpha", "gene_name": "Pilrb1", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MAQILLLLLSATCLHTGNSGGYTRKNYFGVNQPAVLSGVQGGSIEIPFSFYFPWKLAKDPQMSIAWRWKEVHGEFIYQSTLSFIHEHFKDRLILNWTQGQTFGVLRILNLKENDQATYFSQVCLQTTEGMKCWQSIPGTKLIVTHGVICSLLISPQLSYDHEDPLHHHLCRPHSWPGEHKGPKESFTAEPGGHHWDGRGQSCSHHPPLRMDDLSVVEAKASRVTPKPQPE", "length": 230 }, "evidence": [ { "id": "G3MZM9", "url": "https://omabrowser.org/oma/group/G3MZM9/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "A0A8I6A5T5-1", "protein_name": "Large ribosomal subunit protein eL21", "gene_name": "Rpl21l1", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MTNTKGKRRGTRYMFSRPFRNHGVIPLATYIRIYKKGDIVDIKGMGTAQKGMPHKCYHGKTGRAYNVTQHAVGIIVNKQVKGKIPAKRINVRIEHTKHSKSRDGFLKRVKENDQKKKEAKEKGTWVQLKRQPVPPREAHFVRTNGKEPELLERSPYEFMA", "length": 160 }, "evidence": [ { "id": "G3MZM9", "url": "https://omabrowser.org/oma/group/G3MZM9/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "A0A8I6A8T3-1", "protein_name": "Olfactory receptor", "gene_name": "Or1o11b", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "RMNCSQAPGFILLGLSRDPEKWQLFFSVFLVLYLLGLSGNLLLLLAIGADVHLHTPMYFFLSQLSLVDLCFITTTAPKILQTLWTGDGSISFSGCLTQLYFFAVFADMDNLLLAVMAIDRYAAICHPLLYPLLMTPCRCGVLVSGSWGVAHCVSLTHTLLLSQLYFHTNQMIPHFFCDFGPLLLLSCSDAHLNEGLMMALAGVFGISALLCIVSSYSCIFYAVARVPSAQGKRKALATCSSHLSVVLLFYSTVFTTYLKPPSSSYSSGEVVAAVMYTLVTPTLNPFIYSLRNKDVKSSLRRILNMVKSPD", "length": 310 }, "evidence": [ { "id": "G3MZM9", "url": "https://omabrowser.org/oma/group/G3MZM9/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "A0A8I6A969-1", "protein_name": "Uncharacterized protein", "gene_name": "ENSRNOG00000067430", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MFFLFWTFPGLELDKLALLSFESSSSIHPRACASTPAFQRSHNPGDAAQQEAKQREAEMRNSILTRVLDQSAWVRLSDLALVKPDKTKAVEHRVQMARYGQLSGTVSEQGFIETPEKVSQQTEEKATVKFNRREVTDSDEDDDY", "length": 144 }, "evidence": [ { "id": "G3MZM9", "url": "https://omabrowser.org/oma/group/G3MZM9/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "A0A8I6A9H4-1", "protein_name": "NAD(P)(+)--arginine ADP-ribosyltransferase", "gene_name": "Art3", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MGQATARGVIKRKAFPGRQLSLSTTSCPGGKITPAESGNRFESGHHLNVLQRHKRQKRKMKMGHFELVTTLLAAMVLMDVFQVQAEVLDMAENVFDDEYLKCNSRMEMKYIPRMHGEELANDELLQSVWDKAGIQWEAQKAQLSLPKNFKDAYGIALTAYVTEAQDQSPFYHTFNRAVKIAGLSRRRYIYNFPFKAFHFYLVRALQLLRRPCEESYKNVVYSTSPNISFAFGEQNQARLGNFTLAYSAKPQTANEQRLLTIQTCFGVAVGKLLNKESEGIVLIPLSEVFQVSRKGTDDDLILHSINSTCSYYECSFLGGLKAGSCTTNPENPDPGYLNNPDLDSQKLEDSGRKSLDSVKMPEIKVLQGEENPLLPDEKPEDRNRGKANVPTPGLVPVPGPKSHPSSSSGHRLLPSDTASTILLIAAAVDFIAL", "length": 433 }, "evidence": [ { "id": "G3MZM9", "url": "https://omabrowser.org/oma/group/G3MZM9/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "A0A8I6AA84-1", "protein_name": "Ankyrin repeat domain 10", "gene_name": "Ankrd10", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MSAGAGAGVEAGFSSEELLSLRFPLHRACRDGDLVALCSLLPHTPRAHLAAEDSFYGWTPVHWAAHFGKVGAGTLRRHFPRGVLLGSERTPPCLESAATARSAPPAPPEGSRAHVQQSGLGVKGWGRGGAEAALAPPGVQGACAAARSPGPRGARGVMGGGAEMGSVWPAPRRTQGACAHLWLFRAGRADRMQLRRFARRPSGFGEWCGRLLLEARREPGASRSCLMETGRRAPLRHKGMDAALAAGGVRSAPAVVDGGLAARPTGPLSQLGPPCLECLIQLVRAGASLNVSTTRYAQTPAHIAAFGGHPQCLVWLIQAGANINKPDCEGETPIHKAARSGSLECISALVGNGAQTDLRNASGLTAADIAQTQGFQECTQFLLSLQNHQMSRFCPNGTLSGGHENILPNHINLGTNRKRCLEDSESLGVKKARTRVPSLDHTMPLANGDAEDDADRMHVDREFAAVSDMKNSSSVLNTLTNGSVINGHLDFPCVAQLNGMESRSDPCLTGSNGISNGQPFPSGQGPVCANGTEEPEKTMGVNPEMCGSLHLNGSPSSCVASRPSWVGDIGESLHYGHYHGFGDTAESIPELSSVLEHSSCVRVEQRYDSAVLGAMQLHHGS", "length": 621 }, "evidence": [ { "id": "G3MZM9", "url": "https://omabrowser.org/oma/group/G3MZM9/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "A0A8I6ABF4-1", "protein_name": "Nuclear transport factor 2", "gene_name": "AABR07018058.1", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MGDKPIWEQIGSSFIQNYYPLFDNDRTQLGAIYIGASCLTWEGQQFQGKAAIVEKLSSLPFQKIQHSIMAQQYQPTPDSCIISMVVGQLKADEDPIMGFHQMFLLKNINDAWVCTNDMFRLALHNSS", "length": 127 }, "evidence": [ { "id": "G3MZM9", "url": "https://omabrowser.org/oma/group/G3MZM9/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "A0A8I6AC04-1", "protein_name": "Vomeronasal type-1 receptor", "gene_name": "Vom1r38", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MSMLSQNKTLKSIEEVALHVILLCQVGVGTVANFLLFIHNFSVILTNCQLTPIQVIVTNLAVASAFNLLLLAFPNNVTLFVPRKAPSDLSCKLWYFICLVARSTNLSSTCVLSTYQFVMLLPGNWSRVILKGRAPKIVNYSCYGCWIFSVLNNAYIPVKVSGPQKTQNDTDFKDKWVCSTSGFSVGMSFLRFAHDALFISIMIWTNVSMVILLNRHHHRLQHIHSSNQDHRAYADTRAAHTILMLVVTFLSFYLLDCICTFFHISFVDSRLLLRRIKEVLTASFPTISPFLLIFRGPKNPCSLLSRS", "length": 307 }, "evidence": [ { "id": "G3MZM9", "url": "https://omabrowser.org/oma/group/G3MZM9/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "A0A8I6AC51-1", "protein_name": "Non-histone chromosomal protein HMG-17", "gene_name": "Hmgn2", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MPKRKAEGDAKGDKAKVKDEPQRRSARLSAKPAPPKPEPKPKKAPAKKGEKVPKGKKGKADAGKDANNPAENGDAKTDQAQKADGAGDAK", "length": 90 }, "evidence": [ { "id": "G3MZM9", "url": "https://omabrowser.org/oma/group/G3MZM9/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "A0A8I6AC66-1", "protein_name": "Eukaryotic translation initiation factor 6", "gene_name": "Eif6-ps1", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MVVRASFENNCEVSCFARLTNTYSLVAIGGSENFYSVFEGELSDTIPVVHASIASCRIIGRGTSVWGTGMGYWYPTTTTDQELQHIHDSLLDSVQIRRVEEGLSALDNVTTCNDYVALVHPDLDRETEEILAGVLKVEVLTVADQVLVGSYCVFSNQGGLVYPKTSIEDQDELSSPLQVPLVAGTVNRGSEVIAAGMVVNDWCAFCGLDTTSTELSVVESVFKLNEAKPSTIATSMRDSLIDRLT", "length": 245 }, "evidence": [ { "id": "G3MZM9", "url": "https://omabrowser.org/oma/group/G3MZM9/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "A0A8I6ACC5-1", "protein_name": "Uncharacterized protein", "gene_name": "ENSRNOG00000069094", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "LPLLAFEKYVVCDGELQRLQVSCEVLGDVDPPQRLSASVVQMKQSVVEFLGTLVEQDAQGAAEDMDNALVGDNEEAEGENNSTRTNSDGPFTERPNQRLNNR", "length": 102 }, "evidence": [ { "id": "G3MZM9", "url": "https://omabrowser.org/oma/group/G3MZM9/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "A0A8I6AEL7-1", "protein_name": "Protein phosphatase 4 regulatory subunit 3C like 1", "gene_name": "Ppp4r3cl1", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MEDKLYRVKVYVMMEDKQWKDIGAGQISSKYIDRLQGVCLLVHSESDGSPILECKIQPNVPYQKHQGKVIIWSEAKNHGTAIHFQEPNDCQETWEVICQVQGKDPNVEITQLLTDDLESFKDMLLSWNKVEMSSCELHTLENIADLLSFVNEAPSHKKILTLVLEKEGYIKKLLQLFKTCEKHQNIDGLHYLNNIIRGILFLDNIHLFNIMFSDEFIMDVVGCLEYGPGLDEPKQHRQFLTQNVKFKNVMQITHSQLRKKIQQTYRMQYIYDIVLPTPSIFEVNLLHDLSTMIFFNKIEIITMLQEDEHFLLEVLAQLKDNTVSNERRHELLLFFKEFCAFAKTLHFQKKNTLLKTLIKLGIISALKVVVHMHDYQIQVAALELFAHLVEYSPRLIRAYAMKEAQYSEDNDGLLINIMIKQMTCDSDPEFSRSIILTTVLHAILDPENMRVTTKGHERRKFLNYFYRHCMNKLIEPILSITVENNSDDNRVNICPDNYQNAQLLGAILEILTFCVQYHSKYVKNYIISKNLLSRILILMSSKHTFLILCAVRFMRKMIGLKDKMYNLYIVEKNLFEPVVNAFMHNGHRYNMLNSAIIELFEFIRQENIKSLIANIVEKFFMFFESIQYVQTFKGLKTKYEEEKKKKRERQLRKSLHNIIYQRIYCRHIKAMEVKVKADIFCRQITDKEEEREKGGGGGEGGGGRGGEGEGGREGGGREGEGGGGGKGGRGEGGAVLSMGSDIPSHYDMFVKINEMNERENVIECRKRKSSATSEYSTSCGDTSDNGISTVYCSSLVPLVDYAYDTDGEDDDGSYGNNENEEEEEEEEEEEPPKKKPYFHP", "length": 840 }, "evidence": [ { "id": "G3MZM9", "url": "https://omabrowser.org/oma/group/G3MZM9/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "A0A8I6AFG0-1", "protein_name": "Cytochrome b5", "gene_name": "ENSRNOG00000064959", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MFAKEKGKFEDMAKDVKCYTLGEIQKHQDIKNSWAMLHHRVYDLTKFLEEHLGEEEVLRERAGGHASENFEDVGCSTNVQGLSKVHIIGLFHPALITTIKLNSNWWDQLCSPTSQVVVAHTFNPSTREVGAVGFP", "length": 135 }, "evidence": [ { "id": "G3MZM9", "url": "https://omabrowser.org/oma/group/G3MZM9/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "A0A8I6AGM4-1", "protein_name": "Proline rich 18", "gene_name": "Prr18", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MLRLLGRVMSFSPMPPPPPPPPPPARTQGGPAARQLSRRPCGPPAASPPAPAAAAAGEKKRRPPEMLLSSSWPSATLKRPPARRGPGLGPGTPQPPTSARVPPQPSPGRGGTSATCSAPRRIACSHIPAGSTASGTSAGAGAGPEDATRFSLSLTPEAILVIQRRHLEKQLLARPRRPFPAPSADPRRPLVPCPRTRSSTLRRGGPTSVPDAPLAVAVSSRPPRASLLPGGLQATMPSPRPSSLRPVLKVSLLNEKHKYDDEEYEEEVEVVDEGLVRKCTEWLRGVESAAAARGRTGHLDSLPHLSTL", "length": 308 }, "evidence": [ { "id": "G3MZM9", "url": "https://omabrowser.org/oma/group/G3MZM9/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "A0A8I6AGS9-1", "protein_name": "Olfactory receptor", "gene_name": "Or5aq7b", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MEVWNSTGVKEFILIGLTENPNWQVPLFLLFCIIYFIILVGNCGMIFLIWLNVQLHTPMYFFLSNLSFCDICYSTIIAPKMIINFLSEHKSTRLFACILQSFFFAVYATTEVVLLSMMAYDRYVAIANPLMYTVIMTQSICTQMILASYLTGLINSLIHTIGLLKLNFCGPNIVNHFFCDVPPLLKLACSDSHINEILLLVFSGIIAISTLIIVIVSYIHIIIAILRIRSAMGRGKAFSTCASHLTAVALFYGSLTFSYIQPSSQYSMEQEKVSAVFYTLVIPMLNPLIYSLRNKDVKEAAQKLMLGKRNAC", "length": 312 }, "evidence": [ { "id": "G3MZM9", "url": "https://omabrowser.org/oma/group/G3MZM9/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "A0A8I6AIA3-1", "protein_name": "Uncharacterized protein", "gene_name": "ENSRNOG00000065493", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MIFVPFFPHPGSIRKDGVVYAHTMENSSNSPRETREPAPLRRTWRGCFQRALPRVSKFFRRGRGSTGGWDNGSPRQGPMHSDQDLRHLRSLLSKESCPVMSK", "length": 102 }, "evidence": [ { "id": "G3MZM9", "url": "https://omabrowser.org/oma/group/G3MZM9/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "A0A8I6AK52-1", "protein_name": "Olfactory receptor", "gene_name": "Or9s14", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MAIEVHRNGSLSAMSLQGFVLLGFRGGAETQALLFTVFLVLYVVTVLGNLTMIMVITLDARLHSPMYFFLKNLSFVDLCLSTVVVPNALASIFFSSKTISFAGCATQFFFFSLLAATEAVLLAVMAYDRFMAICSPLRYPVTMCPMTCVRLVLGTFCVACLNSIVQTSLTFRLPFCSSNRIDHFYCDVPPLLQLACASTALNELVMFGICGFIIVCAVFVVIISYVYITVTILRMHSGSGRHKLFSTCGSHMTAVSLFYGTGFAVYGQPGGVASMEQGKVVSIIYILIIPMLNPLIYSLRNKDVKDALRRLGQRHSLAKESG", "length": 322 }, "evidence": [ { "id": "G3MZM9", "url": "https://omabrowser.org/oma/group/G3MZM9/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "A0A8I6AMC4-1", "protein_name": "Retinoic acid early-inducible protein 1 domain-containing protein", "gene_name": "ENSRNOG00000068014", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MCVFKNAWGHRNMCSMALCSQFGTHLHVSLTDAHSLSCNLIIRSPTKAEPLRYEGHCSMDEIVFLSFNNVNKTMPLGNQEKMANATKVQKCLTQWIDLLGQDLRDKVSEIKVHTTKTSGHPTLRVTMLSKHRHGEIIGASWEFNISENYSFILDLKTMKWKPQDIMKEWKDDETLMKHLNLSIVECSQKFNEFLNQHEERTSRYYLDSALPPAPPPLFKGFTILLWHSYTPAISPTSSDTHSSFINFRDGLIDINFPL", "length": 258 }, "evidence": [ { "id": "G3MZM9", "url": "https://omabrowser.org/oma/group/G3MZM9/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "A0A8I6AMN7-1", "protein_name": "60S ribosomal protein L7a", "gene_name": "ENSRNOG00000070681", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MLKGKKAKGKKVAPAPAVVKKQEAKKVVNPLFEKRPKNFGIGQDIQPKRDLTRFVKWPGYITLQRQRAILYKRLKVPPAINQFTQALDRQTATQLLKLAHKYRPETKQEKKQRLLACAEKKAAGKGDVSTKRPPVLRAGVNTVTTLVENKKAQLVVIAHDVDPIELVVFLPALCRKMGVLYCIIKGKARLGRLVHRKTCTTVVFTQVNSEDKGALAKLVGAIRTNYNDRYNEIRRHWGGNVLGPKSVARIAKLEKAKAKELATKLG", "length": 266 }, "evidence": [ { "id": "G3MZM9", "url": "https://omabrowser.org/oma/group/G3MZM9/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "A0A8I6AMX9-1", "protein_name": "Ribosomal biogenesis factor", "gene_name": "Rbis", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MAKNKLKGQKSRNVFHIASHKPLKAKNKAKPVTTNLKKINIMNHEKVNRMNRAFVNIQKELANFSKSLSLKSVQKELHHEKEPANVDEATRLMAQL", "length": 96 }, "evidence": [ { "id": "G3MZM9", "url": "https://omabrowser.org/oma/group/G3MZM9/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "A0A8I6ARJ3-1", "protein_name": "G-protein coupled receptors family 1 profile domain-containing protein", "gene_name": "Or8b101l1", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MTLGNVSSVKEFILLGLTQQPELQLPLFFLFLGIYVVSVVGNLGLIVLIVLNPHLHTPMYYFLFNLSFTDLCYSTVITPRMLVGFVKQNIISHAECMTQLFSFCFFVIDECYILTAMAYDRYAAICKPLLYQVTMSHQICLLMTVGVYMMGFVGAMAHTGSMLSLTFCEGNIINHYMCDIPPLQKLSCTSTSINELVVFTVVGVNVIIPTLTLFVSYTLILSNILSIHSAEGRSKAFSTCGSYIIAVSIFFGAVLFMYFKPSSASVDGDKVSTIFYTILGPMLNPFIYSIRNKDVHVALRRTLKKRIFT", "length": 309 }, "evidence": [ { "id": "G3MZM9", "url": "https://omabrowser.org/oma/group/G3MZM9/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "A0A8I6ATM0-1", "protein_name": "ELAV-like protein", "gene_name": "Elavl3", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MKDAGAGSCRYKGLGAAAVRPRARSAQRGPVGGREGGREERTHYPAPDRPDRGPAAEGRAAEISVGKSDFCGPRGAALRAPSTARPLPPSTCRQGSGRRSAHPQARVSSRPSRAPPPPSSPLRRPQSQTPGRDPGVSTRRPPRSARPPEPPSIRTAPAGHTRMVTQILGAMESQVGGGPAGPALPNGPLLGTNGATDDSKTNLIVNYLPQNMTQDEFKSLFGSIGDIESCKLVRDKITGQSLGYGFVNYSDPNDADKAINTLNGLKLQTKTIKVSYARPSSASIRDANLYVSGLPKTMSQKEMEQLFSQYGRIITSRILLDQATGVSRGVGFIRFDKRIEAEEAIKGLNGQKPLGAAEPITVKFANNPSQKTGQALLTHLYQSSARRYAGPLHHQTQRFRLDNLLNMAYGVKRFSPIAIDGMSGLAGVGLSGGAAGAGWCIFVYNLSPEADESVLWQLFGPFGAVTNVKVIRDFTTNKCKGFGFVTMTNYDEAAMAIASLNGYRLGERVLQVSFKTSKQHKA", "length": 522 }, "evidence": [ { "id": "G3MZM9", "url": "https://omabrowser.org/oma/group/G3MZM9/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "A0A8I6AUS4-1", "protein_name": "Ubiquinol-cytochrome-c reductase complex assembly factor 3", "gene_name": "ENSRNOG00000062467", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MQTAAGKTLAVVAVLGAGAGVGSILFALVTPGELQKQSMLQEMPERDSRRRNEAVRTKELVIATLKDAAATKGNVAWRRTGQLEGQGRMCGTKGTNKCSLPIKWISQLDI", "length": 110 }, "evidence": [ { "id": "G3MZM9", "url": "https://omabrowser.org/oma/group/G3MZM9/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "A0A8I6AWY6-1", "protein_name": "Uncharacterized protein", "gene_name": "ENSRNOG00000065059", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MAKATKKSKNTTSDVEPSTSSAKSKKAKTCYQYQTRAGEKKSRWSGSDCSVNVQKTTKKAKRTLPRIAENNTSEKTVPPTKKTKRAKDEQLFGHYHRLMDEISTSTERGPEQSSTDSSSASTSDEESQ", "length": 128 }, "evidence": [ { "id": "G3MZM9", "url": "https://omabrowser.org/oma/group/G3MZM9/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "A0A8I6B5G4-1", "protein_name": "protein-tyrosine-phosphatase", "gene_name": "Ptp4a1l1", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MARMNCPAPVEVTYKNMRFLITHNPTNATLNKFIEELKKYGVTTIVRVCKATHDTTLVEKESIHVLEWHFDDGAPPSNQIVDDWLSLVKIKFPEEPGCRIAVRCVAGLGRAPGLVALALIEGGMNYEDAVQFIRQKRRGAFNGQQRLPLEKYHPKMWLRFKDSNSHRNNCCIQ", "length": 173 }, "evidence": [ { "id": "G3MZM9", "url": "https://omabrowser.org/oma/group/G3MZM9/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "A0A8I6B646-1", "protein_name": "Ankyrin repeat domain 66", "gene_name": "Ankrd66", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MRSREARLHHQTPGDQEAGAACLLSWGGGGASFHGVNTLTLRPAMMACSTELLKDTDSVMELSKLSDMTKLHQAVAAGDYNSVKKILKKGLCDPNYKDVDWNDRTPLHWAAIRGQMEVIHLLIQYGARPCLVTDVGWTAAHFAAESGHLNVLKTLHALHAAIDAADFFGDTPKRIAQIYGQKDCVDFLDTAEPECRDHRQRGLLFDERDPDWDLKKRELELSLPVPDQNTNKKKKRIRGSTRVNHSKAWRI", "length": 251 }, "evidence": [ { "id": "G3MZM9", "url": "https://omabrowser.org/oma/group/G3MZM9/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "A0A8I6G1V0-1", "protein_name": "Ankyrin repeat domain 62 like", "gene_name": "Ankrd62l", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MSRVAGLSSKKSRWLLQSLLDQQRHSLGTGFESANILLSPKYHLKDKDLRKIHKAARDGDAARVQQLLLGKHCVNDKDKKKRTALHIACAYGHPKVVMALVEGKCEVNATDSEECTSLVKAVQCQEEECATILLENNADPNIVDAQGNSALHYAVYYKNTSLAAKLLDHEVNIEATNKDGFTPFLLAVSENKLKIAKFLLMKNASIHAADNQKRTALMHAVSHDSTNLVRFVLEQGVDLFVKDAFGLTAIDYAADFKYNSNMEILLEYKAKRYEESERANLVEKSSEEDSSRRKDQQSQELENMEKEELTEPGNGTEEQEPDGGVTSVEEPRRLDDRGDDQPQEAVTAPRTREKEQELPFTDMCTVVTGKEDEDESSWDSESVSENLPLIRIGVDGLLLVNGQAVENPEKYLHWLHNRKGEESVPNETKGVGDLQAFTPAEPGLELTSEEKHEELSRNEDCQPQVEEERTQEWSGWGAPEALCAAALDHGDIGSPLTRENGHPRARQSPSVDSEEQDGGSGLNIKEEKTRDHEEWSGDFLMDRTSKESEPAAGDLLQVKDSWSLNDTDPNKGSPAKRKSKEKHKVRGEMNAMEDADDFTPLSESCSDNKAELCCNTHQAETETESCELLTRQTGNMEGGVAGEVLKTEPARSREALKETEETGEGARVKMQLPGKDELYSEDAERQQYDMALSALHLKTKQTVRQLQETQDRQREVVRSSQRMQDHLQKLQAGCSEAEAMVQEQGKKTAELQKLHAGMIHELKEKWETIASKYLPLNIQLKYLEQELLSIKIAQKQYEKLHEDQRTLQRDAVDLQHQVQENMAKLDDEKQAMALRDSNNDSLMSQVELRIKNLESNLQKLQAEKESNERNVEKYLQRYIRERELSKTLSHTLHRTNSKLSRVRTDILLVTERNRTVQNTLTTRPVPKSPGVTEHSAYVNRNPNFIASRNLEAAMSSPQPSPELMRRRLLKKQKNMVKNITEEVDKAAAELESWSLEAYPSGSK", "length": 1003 }, "evidence": [ { "id": "G3MZM9", "url": "https://omabrowser.org/oma/group/G3MZM9/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "A0A8I6G430-1", "protein_name": "Large ribosomal subunit protein eL24", "gene_name": "LOC689816", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MLETCRNLSAIGYIWEDNSTEEYCKSSRRHGRPTSVTMKVNLCSFSGYKIYSGHERLYARTDGKFSSFLMPNVSPHSFPKGTLGKLTGLSSTEENTRKDSRKKFKRKEPTLQKFQRAITGASLADIMAKRNQKPEVRKAQQEQAIRDAKEAKKAKQASKKTAMAAAKAPTKAAPKQKIVKPVKVSAPRVGGKR", "length": 193 }, "evidence": [ { "id": "G3MZM9", "url": "https://omabrowser.org/oma/group/G3MZM9/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "A0A8I6G808-1", "protein_name": "Paired immunoglobulin-like type 2 receptor beta", "gene_name": "Pilrb2l7", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MARILLLLLSAACLHTGNSAGYPKKYDYGVDQPAVLSGVQSGSIEIPFSFYFPWELAKDPQMRIAWRWKVFHGEFIYNSTQPFIHEHFKGRLIMNWTQGQTSGVLRILNLKENDQATYFSRVFLRTTEGMKSWQSIPGTQLIIHALITTPGSPSIIPSAVPTTGLEDTRGQRTPSLLNLGAMVGMVVSKVVVIIPLYGWVIFLWWKQRTQFRRDLVSEHPWKNFVPILPAESSSFL", "length": 236 }, "evidence": [ { "id": "G3MZM9", "url": "https://omabrowser.org/oma/group/G3MZM9/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "A0A8I6GB91-1", "protein_name": "Olfactory receptor", "gene_name": "Or4c117b", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "TNRYYFNIFMIIMQNQSFVTEFILLGLSQNPNVENILCVVFLFIYLATIGGNMIIVVTIIYSPALLGSPMYFFLIFLSLLDACTSSTVTPKMIVDFFYERKTISFECCMTQLFAIHFFTGIEVIILSAMAYDRYVAICKPLHYSSIMTQRLCGILVIVSWAGGFLHSIIQIIFTLQLPFCGPNVIDHYLCDLFPLLKLACTEPHIFVILVFSNSGSISIIIFSILLVSYGIILFSLRAHSSEGRRKALSTCGSHITVVLLFFVPCFLIYARPTSAFSSEKNAFVFATIITPLLNPMVYTFRNKEMKNAIRKMWKRLIMVSCNY", "length": 323 }, "evidence": [ { "id": "G3MZM9", "url": "https://omabrowser.org/oma/group/G3MZM9/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "A0A8I6GF85-1", "protein_name": "Ceramide-1-phosphate transfer protein", "gene_name": "ENSRNOG00000064148", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "HFFLEYLNNLKIMLIFLSPPTGGWASDHHSPTTGTHLRFLNSLGAAFSFISKEVVSKLQIMEHPRSSPQSEHCSSLQSMAAYEVSNKLLDLARRSGPLHSNSGCRTVLCLHRALHWLQLFLEGLRTSSEDARTSTLCTEAYSAMLCAYHSWIRQAVTVAFCALPSGKVFLEMLGEALPFMEQMCDISQFYVEHFLLDLP", "length": 199 }, "evidence": [ { "id": "G3MZM9", "url": "https://omabrowser.org/oma/group/G3MZM9/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "A0A8I6GFV7-1", "protein_name": "Olfactory receptor", "gene_name": "Or1f21c", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MSSTNQSSVTEFLLLGLSRQPQQQQLLFLLFLTMYLATVLGNLLIILAISTDARLHTPMYFFIMILSFTDVCFSSTTVPKVLANYMLRSQTISFSGCLTHLYFLCVFADMDNFLLAVMAYDRFVAICHPLHYTTKMTNKFCVLLIVGSWVLTNLNALLHTLLMAQLSFCGDNIIPHFFCDATPLLKLSCSDTHLNDLMILTEGTMIVVTPFFCILISYIHITCAVLRVSSPRGGWKAFSTCVSHLAVVCLFYGTIISLYFNPSSSHFAGKDMAGAIMYTVVTPMLNPFIYSLRNRNMKGVLRKVLILRFPSKQ", "length": 313 }, "evidence": [ { "id": "G3MZM9", "url": "https://omabrowser.org/oma/group/G3MZM9/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "A0A8I6GGC1-1", "protein_name": "Histocompatibility 60b like 1", "gene_name": "H60bl1", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MAKGATSKCNHSLTLSLLVLLNSLGTMQVDGTDSLSCNFTVQYKVSLGQCSVNGMTVLCFDDVRQNSPVCKTEKKGNATKLCNDLNQCLSYSFYEMMKLESGLFESKGNHTLRVTVQSQYNQGEFMDGCWAFMIDRQYPFYFYPKNMTWRENQPNAIKTMSQWENNRELFQSLKFLSTGDFSLCLKKLLTDSRELTRSTIKAPDTTQPTSTTQSPSTGNSTPAMSSNQSPSTGNSTQPTSTTDYLIVFEFTAIFLALIVVSMEKKKVLPAAPLPLQYELQSPSPAVLEES", "length": 290 }, "evidence": [ { "id": "G3MZM9", "url": "https://omabrowser.org/oma/group/G3MZM9/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "A0A8I6GIM2-1", "protein_name": "Olfactory receptor", "gene_name": "Or4x11c", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MADLFNVTEFIFLGLSPNKEVQRVCFVLFLLLYMAIVLGNLLMVVTVAVSRNLGSPMYFFLSSLSFVEICYSSTTAPKLILDLLAEMKSISVWGCMTQLFFLHYFGGIEIFLLTVMAYDRYVAICKPLHYTSIMNRKVCIVLVGTAWTGGFVHSFAQIVLIFPLPFCGPNTIDHYFCDVLPLLKLACSDTFLIGLLIVANAGTLSVIIFVVLLASYVVILFHLRTLSAEGRRKALSTCGSHVTVVILFFGPCVFIYSRRSDTLPVDKMIAVFYTVITPLLNPLIYSLRSAEVKKAMKNLWFRTMKADEK", "length": 309 }, "evidence": [ { "id": "G3MZM9", "url": "https://omabrowser.org/oma/group/G3MZM9/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "A0A8I6GJN1-1", "protein_name": "Heterogeneous nuclear ribonucleoprotein A1", "gene_name": "Hnrnpa1-ps20", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "LSQSPPRNRTEQLWKLFIDGLSFETTDESLRSHFERWGTLTDCVVMRDPNTKRPRGFGFVTYTTVEEVDAAMNARPHKVDGRVVEPKRAVSREDSQRPGAHLTVKKIFVGSIKEDTEEHHLREYFEQYGKIEVIEIMTDRGSGQKRGFVFVTFDDHDSVDKIVIQKYHTVNGHNCEVRKALSKQEMASASSSQRGRNGSGNFGGRGGGFGGNDNFGRGGNFSGRGGFGGSRGGGGYGGSGDGYNGFGNDGSNFGGGGSYNDFGNYNNQSSNFGPMKGGNFGSRSSGSYGGGGQYFANPRNQGGYGGSSSSSSYGSGRRF", "length": 319 }, "evidence": [ { "id": "G3MZM9", "url": "https://omabrowser.org/oma/group/G3MZM9/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "A0A8I6GJR0-1", "protein_name": "Aspartate aminotransferase", "gene_name": "Got2-ps6", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MALLHSRMATTFHPGLAAAASARASSWWTHVEMGPPDPILGVAEAFKRDTNSKKMNLGVCAYRDDNGKPYMIPSIRRQRPRLLEKIWTKNAYPSGDWLVFVRLLQRSEPVFCKDILSLAKMSFYPNHPGETTRPSSGMPACSYKVIDTMTHKTCGFDFSGALEDISRIPEQSVLLLHACAHNPMGVDPRPEKWKEMVSVVKKKSLFAFFDMAYQGFASGDGDKDAWAVQHFIEQGINVCLCQSYAKNMGLYGERVGSFTVVCKDEEEAKRVESQLKILIRPLYSSPPLNGARIAATILTSPDLRKQWLQEVKGMADRIISKRTQLISNLKKEGLFHNWQHITDQIGMFFYMIKDGRISVAGVTSGNVCYLTHAIHQVTK", "length": 379 }, "evidence": [ { "id": "G3MZM9", "url": "https://omabrowser.org/oma/group/G3MZM9/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "A0A8I6GL73-1", "protein_name": "Uncharacterized protein", "gene_name": "LOC134481331", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "TALLVSLPEQNLAMARILLLFLSAACLHTGNSSGYRRVNDFGVNQPAVLSGVQSGSIEIPFSFYFPWELANDRSMSIAWIWKYFHGEVIYNSTQPFLHEHFKGRLIMNWTQGQTSGVLRILNLKENDQARYFSRVFLRTTEGMKSWQSIPGTQLIIHALNTTMGSPSIIPSAVPTAGLEDKRGQRNPSLLNLGVMVGMVLAKVVVIIPLYGWMIFLWWKQR", "length": 221 }, "evidence": [ { "id": "G3MZM9", "url": "https://omabrowser.org/oma/group/G3MZM9/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "A0A8I6GLF3-1", "protein_name": "Heat shock protein 90 alpha family class B member 1, pseudogene 13", "gene_name": "Hsp90ab1-ps13", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MPEEVHHGEEEVETFAFQAEIAQLMSLIINTFYSNKEIFLWELISNASDALDKIRYESQTDPSKLDSGKELKIDIIPNPQERMLTLVDTGIGMTKADLINNLGTIAKSEDQTEYLEERRVKEVVEKHLQFIGYPITLYLEKEREKEISADEAEEEKREKEEEDKEDEEKPKIEDVGSDEEDESSKDKKKKTKTIKEKSIDQEELNKTKPIWTRNPDDITQEEYGEFYKSLTNAWEDHLAMTSLSGYVSRMKETQKPIYYISGESKEQVANSAFVERVWKRGFEVVNMTEPIDDYCVQQLKEFNGKSLVSVTKEGLELPEDEEEKKKMEESQTKFENLCKLMKEILDKKVEKVTIPSRLVSSPCCIVTSTCGWTANMERIMKARALRDNSTMEYVMAKKHLDINPDHPMVETLRQKAEADTNDKAVKDLVVLLFETALLSSGFSLEDPQTHSNCIYCMIKLGLGIDEDEVTAEELSAAVREEIPPWRVMRMPLAWKKWIKGSWEAPALCIVSLGLPQQP", "length": 518 }, "evidence": [ { "id": "G3MZM9", "url": "https://omabrowser.org/oma/group/G3MZM9/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "A0A8I6GM54-1", "protein_name": "MAGE domain-containing protein", "gene_name": "Mageb11l1", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MPHDQKSKLHSRENSYQAGGGAQAYGDAEEIAEAAAEAAEESSAKSQSQPGAEYSRNHRAPPKAKPSAKLILSSSSSESDESSHEESEPSVQKDRPFLHQDLIERRVAILLQYLLHNYNLKQLTTKEEMLKVITKKYEKDFPEILRKASEKLEDAFAVEVREVSSSQPSYDLISKLKLPNNGRIRAGKGLPKTGFLMSILGIIFIQGNSASEEDIWKILKKKRIYPGKKHRVFGEPRKLMTQYLVKLKYLEYRQVAHSDPPRYEFLWGPQAHAETSKMKVLEYLAKINKTTPHAISALYQEALKDEKERAEVRDEDNTDTTDQSTEGSPEKSPTASTTPVDT", "length": 342 }, "evidence": [ { "id": "G3MZM9", "url": "https://omabrowser.org/oma/group/G3MZM9/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "A0A8J8YII4-1", "protein_name": "Coiled-coil domain containing 188", "gene_name": "Ccdc188", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MEGPEPLGPCGHSHTQHPPAPVSNNHGGCLNQPCQGFVRWPCLVPLQSTQSLESSRPFPAPGTGSGGPRMRGEAPGMFLSSEGEIPRQRAREPAGARQEEVEVEWDWPLHPGHEQGPPRQTAPPTSGPRPCPCPTLPPRGRATASSRQAPTQLQGGTLESAQQSFLQLEQENHSLKRQNQDLREQLGALLGPGQQFLPLCSEHSSCTALAWVSGNTRSRTHAAAPPAVHSLGPDPGALPQSPESARTRLLEDRAPVQLLRQQELCPGKESFVRQSQSELQQIRLSFERKKMAITEVWDGVAEVHMALNNQATGLLNLKKDIRGVLEQMEDIQLEILGERAQCRTQARKQQQMMEAAGLEAAAGCSAGLHSGLRVRGGPHTLRGAGATPAEPSQRLEAQGLTGSLLTPGGGRLPAFLEQKPSGPSKEARWLVLPQGLRGLTGPCLQHCGTWPLPEAAEKGGGRASPEGWACSWIYSHDTLCM", "length": 481 }, "evidence": [ { "id": "G3MZM9", "url": "https://omabrowser.org/oma/group/G3MZM9/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "A0A8M9PVG7-1", "protein_name": "5-hydroxytryptamine receptor 7", "gene_name": "htr7a", "tax_id": 7955, "organism": "Danio rerio", "sequence": { "sequence": "MVLGDTNRTIIAKSHGETMKSLMAEERARETGASVETFNGIMISEVLVPRLFKIAHESGEVAVAAGSGSMDMKPSSSPILLEMMEVANGTRCAEQILSYGEVEKVLIGGVLTMLTLITICGNMLVVISVCFVKKLRQPSNYLIVSLALADLSVALAVMPFVSITDLIGGRWIFGKFFCNVFIAMDVMCCTASIMTLCVISIDRYLGITRPLTYPVRQNGWCMAKMVLSVWLLSASITLPPLFGWAQNVNDDRVCLISQDFGYTIYSTAVAFYIPMTVMLVMYYRIFRAAKLSAAKHTITGFPRVEQEEVEEDEVEEDGGDGAEEPTGVDCVTVAIKLQREVEECARLPRILRGVGRRCSDRRSISIFKREQKAAATLGIVVGAFTICWLPFFLLSTARPFICGTECSCIPLWVERTLLWLGYANSLINPFIYAFFNRDLRTTYRSLLSCRYRNINRRLSAAGMHEALRLVERPEVVVSG", "length": 479 }, "evidence": [ { "id": "G3MZM9", "url": "https://omabrowser.org/oma/group/G3MZM9/", "database": "OMA" } ], "glygen_name": "Zebrafish", "common_name": "Zebrafish" }, { "uniprot_canonical_ac": "A0A8M9QGZ8-1", "protein_name": "non-specific serine/threonine protein kinase", "gene_name": "pimr118", "tax_id": 7955, "organism": "Danio rerio", "sequence": { "sequence": "MLFTVLGVIALFLRERDTNNTEEEVQNDVPPVRNSDGQEIDDWCKEPSLLEPVSVHSEEPSLEEPVSAHSEEPSLEEPVSVHSEEPSLEEPVSVHSEEPSLVEPVSVHSEEPSLEEPVSVHSEEPSLEEPVSVHSEEPSLKEPVSVHSEEPSLVEPVSVHSEEPSLEEPVSVHSEEPSLEEPVSVHSEEPSLEEPVSVHSEEPSLEEPSLDLSFFSAESSWSEDLSSSFLTVESSWSDDLSSGFLTAESGCGDDEPLFVDSAEPEKLKEDKETQIIEINSHCYAIEAQLGEGGCGAVFSATRLEDGLQVAVKLSDFEEEKRFISVDGFEDPLPLEIALHFLANKGPKVKEIIELLDWKVEADRYFMVLEQPIPCMSLHEFLLDCEGIIPENKLRTIMYQTTVAAQTCCQRGVLHRDIKLENLLINPDTLEVKLIDFGCGDLLTEDSFQYFRGTREYFPPEFSSTGRYHGEPATVWSLGVVLFLLVFYRFPEQSDLPRMNNRRLRIKGLSRDCCDFFHGCLQLDPKDRLELQNLSSHKWIRTRTRRNDENCPNLTDGSSHSNHPITSN", "length": 567 }, "evidence": [ { "id": "G3MZM9", "url": "https://omabrowser.org/oma/group/G3MZM9/", "database": "OMA" } ], "glygen_name": "Zebrafish", "common_name": "Zebrafish" }, { "uniprot_canonical_ac": "A0A8V0WZU8-1", "protein_name": "Ig-like domain-containing protein", "gene_name": "CHIR6B2", "tax_id": 9031, "organism": "Gallus gallus", "sequence": { "sequence": "MAPMVVNLILGWWLVAVSRAQKLPRPSLSLHPSQGASLGDNVTLRCHLPQPAAWVRLYRYQNPTYIEQKDNVQDMAEFSLTSIKQEDAVIYQCQYQGLAPAGTSQKSDPMELLVTDHRYPPPGISLSPKEHVEMGSNITIQCWNKDYGASFLLHKGGHSAPIQHQEPDYWGTATFTLFGVTPADSGTYRCSYRIGGCCLLFSPLGDNVTLEVIPRPAPPGVNGGPSRNLVAAVAGGCAAAIVIITVSFLLVALRRQMQRAERPGATPRSPEAVQFQVSPGDSEGLTYAQLQAVTPSTHPPTSSTTPEPPIIYAEVGTRGPR", "length": 321 }, "evidence": [ { "id": "G3MZM9", "url": "https://omabrowser.org/oma/group/G3MZM9/", "database": "OMA" } ], "glygen_name": "Chicken", "common_name": "Chicken" }, { "uniprot_canonical_ac": "A0A8V0XEA0-1", "protein_name": "C-type lectin like 8, MHCY region", "gene_name": "YLEC8", "tax_id": 9031, "organism": "Gallus gallus", "sequence": { "sequence": "MQSVQIPILKHKVSTPAEGERLNHFSEHKAAPEPTAHQRRRIPTSSDPQLPEEDVQILLLESNTSTPAMGEGDQQETFSEHQAAPEPLGQSGGHQWGSWCHGMGRRRSCVQLIAVHAALGALILMLVVLVISTVCRRAPIPPFSAFGHACPNAWVGFQGKCYYFSKEENDWNSSREHCSAHGASLATIGSAEEMDFMMRFQGPANCWIGLHREEEDAQWTWSDGTAFTNWFELRGGGRCAYLNGDRISSSLCHLHKHWVCSRADHYVLWKQKVHPQ", "length": 276 }, "evidence": [ { "id": "G3MZM9", "url": "https://omabrowser.org/oma/group/G3MZM9/", "database": "OMA" } ], "glygen_name": "Chicken", "common_name": "Chicken" }, { "uniprot_canonical_ac": "A0A8V0XED4-1", "protein_name": "C-type lectin like 18, MHCY region", "gene_name": "YLEC50", "tax_id": 9031, "organism": "Gallus gallus", "sequence": { "sequence": "MQSVQIPILKHKVSTPAEGERLNHFSEHKAAPEPTAHQRRRIPTSSDPQLPEEDVQILLLESNTSTPAMGEGDQQETFSEHQAAPEPLGQSGGHQWGSWCHGMGRRRSCVQLIAVHAALGALILMLVVLVISTVCRRAPIPPFSAFGHACPNAWVGFQGKCYYLSKEENDWNSSREHCSAHGASLATIGSAEEMDFMMRFQGPANCWIGLHREEEDAQWTWSDGTAFTNWFELRGGGRCAYLNGDRISSSLCHLHKHWVCSRADHYVLWKQKAHPQ", "length": 276 }, "evidence": [ { "id": "G3MZM9", "url": "https://omabrowser.org/oma/group/G3MZM9/", "database": "OMA" } ], "glygen_name": "Chicken", "common_name": "Chicken" }, { "uniprot_canonical_ac": "A0A8V0XEJ6-1", "protein_name": "Sulfotransferase", "gene_name": "LOC769841", "tax_id": 9031, "organism": "Gallus gallus", "sequence": { "sequence": "MVCRAAAPNSHPSTMPVHYVTYKGIKFPPAYNSVHSLSFAHNEFLVRDDDVFNITYPKSGTVWMTEILSLIRSHGHPSWNQTVLNSDRMPWFSTRLGLEAALSYPSPRLLTCHLPRHIFPKSFSHSTAKVIYTLRDPRDVVVSYFYFCKMCNSYEDPVSFEQFLRDFLSGELPHGSWFEHVRGWMQMKDRENFFFITYEELKQDLQGSVRRLCHFLGQNLDDDAISSVVQNASFMAMRQNPMCSSILLPADIMDQTKGQFLRKGICGDWKNHFTVAQTETFNRIYLEKMRGLNVAFPWDRDQDPDLTEQ", "length": 309 }, "evidence": [ { "id": "G3MZM9", "url": "https://omabrowser.org/oma/group/G3MZM9/", "database": "OMA" } ], "glygen_name": "Chicken", "common_name": "Chicken" }, { "uniprot_canonical_ac": "A0A8V0XGU1-1", "protein_name": "C-type lectin domain-containing protein", "gene_name": "YLEC62", "tax_id": 9031, "organism": "Gallus gallus", "sequence": { "sequence": "MQSVQIPILKHKVSTPAEGERLNHFSEHKAAPEPTAHQRRRIPTGSDPQLPEEDVHISVLESNTSTPAMGEGDQQETFLEHKAVTEPLGQSGEKPQWGSRCHGTGRRRSRVQLIAVHAAVGALILMLVVLVISTVCRRASIPPFSAFGHACPNAWVGFQGKCYYFSKEENDWNSSREHCNAHGASLATIGSAEEMDFMMRFQGPANCWIGLHREEEDAQWTWSDGTAFTNWFELRGGGRCAYLNGDRISSSLCHLHKHWVCSRADHYVLWKQKVHPQ", "length": 277 }, "evidence": [ { "id": "G3MZM9", "url": "https://omabrowser.org/oma/group/G3MZM9/", "database": "OMA" } ], "glygen_name": "Chicken", "common_name": "Chicken" }, { "uniprot_canonical_ac": "A0A8V0XGW1-1", "protein_name": "NHL repeat-containing protein 3", "gene_name": "NHLRC3", "tax_id": 9031, "organism": "Gallus gallus", "sequence": { "sequence": "MAAPAVLWRLQRLSAAERLEARLSGAVRKEPGRGEARQSEKKPHSPHCPLRCSYACPGRTPMTSESGRKALSHLGRQQQCLNKMAELRARLEAFPAPECLFKTLNPFMGFLRLFFAPQPLGGEQALFRAAQCAEASPRIPAPQAWAGRSRGCHGNAARPASMGRKQAVGPRLVMAGALLTLLGLLWGSQMLKAFDYFSSWKGDGEQQMYKLDISWPKIPEYFSGQTFCVAVDSLHGLVYVGQRGDDIPKVLVFSVEGYFLYSWNDTVEMPHGIFVLNTATDSSVWITDVGSGKYGHTVKQYSPSGKLLQVLGTPGNAGSSLNPLQFDQPAEIFVEESGEMYIVDGDGGMNNRLLKLSQDYKEIWLSGENGTGIGQFKIPHSVTVDPFGRVWVADRDNRRIQVFDKVTGEWLGAWSSCFLEDGPYSVRFTGNYKYLIVAHLNINRLAILAAPPVGEIGDCAIVSTIQLADETKPHLVDVDVKSGAIYIAEIGAQQVQRFVPLS", "length": 502 }, "evidence": [ { "id": "G3MZM9", "url": "https://omabrowser.org/oma/group/G3MZM9/", "database": "OMA" } ], "glygen_name": "Chicken", "common_name": "Chicken" }, { "uniprot_canonical_ac": "A0A8V0XPN1-1", "protein_name": "Ig-like domain-containing protein", "gene_name": "CHIR2A13", "tax_id": 9031, "organism": "Gallus gallus", "sequence": { "sequence": "MAPMAVALILGWWLVAASRAQQLPRPSLSLHPSQGVSLGDNVTLRCHLPRPAAWVWLYLEGRWSYAKYIDKKQDTTEFSFLSASHDQAGTYLCQYQVSESEDVSVTSDPVKLVLTDRSFPPPHISLHPEERVGTGTNVTICCWNKDYGATFLLHKDGRSDPIQRLVPDDVGAVSFTLFGVTPADSGTYRCSYHPKNYPFLSSPLGDSVTLEVTPTPAPPGAELVSRGNLVVAVVRGCAAALIFGLGVFFVIDARSLWIRRDESLGGEGI", "length": 269 }, "evidence": [ { "id": "G3MZM9", "url": "https://omabrowser.org/oma/group/G3MZM9/", "database": "OMA" } ], "glygen_name": "Chicken", "common_name": "Chicken" }, { "uniprot_canonical_ac": "A0A8V0XPP6-1", "protein_name": "SUN domain-containing protein", "gene_name": "LOC776146", "tax_id": 9031, "organism": "Gallus gallus", "sequence": { "sequence": "MEQQGHGERGNWQTKVWKTVALVLVTVAVASFGVYCVGGLVEGIKTTAGVTARLVRRDGEIVSLDEELAKVQRQLHVLQWRARDITERALHEALRRTELPGFTGEAVQKIIHQVLEKLEESPFQMTNYASKTSGAAIVRSKTSPSWIGSGRVFWQSLPLVAYMRPPEVILEPDNHPGNCWPFPGSQGHVFIKLPVAVFPTAVTINHGVPAAAYHADSISSAPKDFAVYGLQEEDDETGTLLGEFIFMPGQAPGQTFQLKNEHSAFIKYVRLQVLSNWGHPEYTCVYQFRLHGDPAPDGDARGKLSA", "length": 306 }, "evidence": [ { "id": "G3MZM9", "url": "https://omabrowser.org/oma/group/G3MZM9/", "database": "OMA" } ], "glygen_name": "Chicken", "common_name": "Chicken" }, { "uniprot_canonical_ac": "A0A8V0XQE0-1", "protein_name": "Ig-like domain-containing protein", "gene_name": "CHIR6A8", "tax_id": 9031, "organism": "Gallus gallus", "sequence": { "sequence": "MEPMAVNLILGWWLVAGSRAQQLPRPSLSLHPSRGVSLGNLVTLRCHLPRLAAWVWLYRGGGWSYKKGKKKEQDAAEFSFASTLREHAGRYRCQYRVYESAEVSVESDPVELVLTDVRYPPSSISLQPEQHVGTGTSVTIHCWNKDYGATFFLHKDGSSDPLQRQDSSGGGTATFTLFGVTPADSGTYRCSYRHWRYAFMSSPLGDSVMLEVTPTPAPPGAELVSRGNLVVAVVRGCAAVLIFALGVFFVIDARSLWIGRDESLGGKGI", "length": 269 }, "evidence": [ { "id": "G3MZM9", "url": "https://omabrowser.org/oma/group/G3MZM9/", "database": "OMA" } ], "glygen_name": "Chicken", "common_name": "Chicken" }, { "uniprot_canonical_ac": "A0A8V0XTD2-1", "protein_name": "Coiled-coil domain containing 97", "gene_name": "CCDC97", "tax_id": 9031, "organism": "Gallus gallus", "sequence": { "sequence": "MKEDPKEAEGPTASKWIPIASNGNPTASKWIPIASNGDPTAPKWVPISSNGDPNWVPISSNRDPMASKWIPVSSDRDPTVTKENPPSSNETPAAEWDPKVPPEGRPVEEGDPKASPTEDPPAEPDPKASNCAPLSSHWAPEAAVWDPTSPHRDPTAEPQCSASPEQHRAAQRDPASPMEEDRYPATHGVRPATRADPAPYGDHPEAEEDPLPAAVEAMLAAVAASPVRVRSQQQGDPELTAAERRRDLRALFLRKPLVFLERFHGALQAEHLPCFAHLPPRYEVAFYCRQVRARRQQNPQTGLSRWPRRPGARTRLRNRRYAALRQLIAGGEYFSEEEMRAREPLLYEHYIGQYRDAETPPGTPPCPPHPGTPPGTTWAAALLRSVEEAAVQQRLQRQRLREGDSGEEDEDEDEAEEPHIPDAGELEVLREEFRSRMYQRFLDGEDRDFDYSQVDENPDMDNLDIESRDAEERYFDEEEPSAAPQLE", "length": 487 }, "evidence": [ { "id": "G3MZM9", "url": "https://omabrowser.org/oma/group/G3MZM9/", "database": "OMA" } ], "glygen_name": "Chicken", "common_name": "Chicken" }, { "uniprot_canonical_ac": "A0A8V0Y889-1", "protein_name": "Transmembrane protein 65", "gene_name": "TMEM65", "tax_id": 9031, "organism": "Gallus gallus", "sequence": { "sequence": "MSAWLGRAVLLLGRPGGPAAPSSSSRLCSLRGPPRCCCRRRLSSLRGGADGLLPARGAPPGRALGTHPKKEPMEALNTAQGARDFIYSLHSTERSCLLRELHRFESIAIAQDPIAARASCQQYGETWAHQEPSGACSSVHSQAYHQKEAVPSSNCPSTKYDRTHYLWPPLMAEAAGKPGRCPHCCAEGWSSEKLEVAPPSPGQLRHVFFHNALPFVGFGFLDNAIMIAAGTQIELSIGVVLGISTMAAAALGNLVSDLAGLGLAGYVEALASRLGLSIPDLTPKQADMWQTRLSAHLGKAIGVTVGCILGMFPLLFFGDEEEKLEEKN", "length": 328 }, "evidence": [ { "id": "G3MZM9", "url": "https://omabrowser.org/oma/group/G3MZM9/", "database": "OMA" } ], "glygen_name": "Chicken", "common_name": "Chicken" }, { "uniprot_canonical_ac": "A0A8V0YA34-1", "protein_name": "SWIM-type domain-containing protein", "gene_name": "LOC100859602", "tax_id": 9031, "organism": "Gallus gallus", "sequence": { "sequence": "MAERGQLPPYAKRLCCRPGYGSGCRLGQQAGDTGPGSGTFCAGPSSAAAAAAAAAAATAASLVLLPLGKTQSPESLLDIAARKVAEKWPFQRVEEQFERIPEPVQRRIVYWSFPRSEREICMYSSFDTGAEGFTAPGSAAGNTASGGAVDAVADENRLPFRRGMALLDGGCVDNVLQVGFHLSGTVTEPAMQSEPETVFNVAISFDRCKITSVTCSCGNKDIFYCAHVVALSLYRIRKPDQVKLHLPISETLFQMNRDQLQKFVQYLITVHHTEVLPTAQKLADEILSQNSEISQVHGAPDPTAGASIDDENCWHLDEEQVQEQVKLFLSQGGYHGSGKQLNLLFAKVREMLKMRDSNGARMLTLITDQFMADPRLLLWRQQGTAMTDKYRQLWDELGALWMCIVLNPHCKLEQKTSWLKQLKKWNCVDVCPWEDGNHGNELPNLTNALPQGANANQDSSNRPHRTVFTRAIEACDLHWQDSHLLHIISSDLYTNYCYHDDTESSLFDSHGWPLWHEHVPTACARVDALRSHGYSREALRLAIAIVNTLRRQQQKQLEMFQARKKELLYRGITSITNLEGWVGHPLDPIGTLFSSLMEACRVDDDNFHGFSDFMENTSQHKSLEYQHLPAHKFLEEGESYLMLAVEVALIGLGQQRIMPDGLYAQEKVCRNEEQLISKLQEIELDDTLVKIFRKQAVFLLEAGPYSGLGEVIHRESVPMHTFAKYLFTSLLPHDAELAYKITLRAMRLLVLESTAPSGDMSHPHHIASIVPNRYPRWFNLSHIESQQCELASTMLSAAKGDVQRLETVLQSIQKNIHSSSHIFKLAQDAFKIATLTDSLPDITLLKVSLELGLQVMRMTLSTLNWRRREMVRWLVTCATELGVHALDSIMQNWFTLFTPTEATSIVATTVMSNSTIVRLHLDCLQQEKLAGSARTLALQCAMKDPQNCALSALTLCEKDHIAFETAYQIVLDAATTGMSYSQLFTIARYMEHRGYPMRAYKLATLAMTHLNLSYNQDTHPAINDVLWACALSHSLGKNELAAIIPLVVKSVKCATVLSDILRRCTLTTPGMVGLQGRRNSVKLMSLDKAPLRQLLDATIGAYINTTHSRLTHISPRHYGEFIEFLSKARETFLMSHDGQIQFTQFINNLKQIYKGKKKLMMLVRERFG", "length": 1168 }, "evidence": [ { "id": "G3MZM9", "url": "https://omabrowser.org/oma/group/G3MZM9/", "database": "OMA" } ], "glygen_name": "Chicken", "common_name": "Chicken" }, { "uniprot_canonical_ac": "A0A8V0YDY5-1", "protein_name": "SKA complex subunit 1", "gene_name": "SKA1", "tax_id": 9031, "organism": "Gallus gallus", "sequence": { "sequence": "MEAEGLEALSRHLAAKIGLIKRLLQLRGLGRREMLAEVGMEVAVLHGLLGRMEEEVNQRRQLAAALQEMRKRAEKEKWEAERLQLVKKAAKEAPLVNDAPLISDEEFESVPGYMRGRLTLAQTNAALRALHAAAASKYRLLRHPPKSLPSSSRALCHRFREEETKETQGLTFVVEADLKEFTQLKVDRTFHRIVGVLRHCRRLREVRGARLVRYVLP", "length": 217 }, "evidence": [ { "id": "G3MZM9", "url": "https://omabrowser.org/oma/group/G3MZM9/", "database": "OMA" } ], "glygen_name": "Chicken", "common_name": "Chicken" }, { "uniprot_canonical_ac": "A0A8V0Z0M2-1", "protein_name": "Tumor necrosis factor ligand superfamily member 10", "gene_name": "TNFSF10", "tax_id": 9031, "organism": "Gallus gallus", "sequence": { "sequence": "MLPAGGPSPAHTCGAVLVAAVLLQSVCVAVTYIYFTNELKQFANADLVHSCERGHPLSPPPPPDVPQTAVTRPTKAEGGAAPVGASCSIGQSRRAQSDLRQRAANAASPQHGPPCAARSRARCSCPRCTAGPRVCRRTQQKLWDTYSRSGTACLTGEELGDLIQNLDVVESKDRVADPCWQVKWHLGKLIKKMMSRILQENMSAINGDRTQALPRRDEPPQGPTLRIAAHLTGSSKRSSASPHIDYLSYRGIGHKIHSWESSRRGHSFLYNVELWNGELVVPQTGFYYIYSQTYFRFRENEDEDSGLLERIKNPKQLVQYIYKLTNYPDPILLMKSARTSCWSKKAEYGLYSIYQGGVFQLKREDRIFVSVSNSDIVDMDKEASFFGAFMIS", "length": 392 }, "evidence": [ { "id": "G3MZM9", "url": "https://omabrowser.org/oma/group/G3MZM9/", "database": "OMA" } ], "glygen_name": "Chicken", "common_name": "Chicken" }, { "uniprot_canonical_ac": "A0A8V0ZCD9-1", "protein_name": "Mab-21-like HhH/H2TH-like domain-containing protein", "gene_name": "LOC124418390", "tax_id": 9031, "organism": "Gallus gallus", "sequence": { "sequence": "MALVLVLALLVRALIVSGSDHAVMLERVQQHEKEQRNGEQSWVDMSALLFTLLHYWKIWFCTGLFVFLFWNMWRSLKRKQHEEGGQQEQQEREEQVEEVEREEQQEQVEEEEQLERVEELEQEDQVEHVEQEEQEEREDQGEQVQQEEQVEEVEQEDEEEEYFHHSALTRYIARRAWEKMQGKATKCVLVEELMSDLLQTYTFVCSNSFYPVLQPAIGVGSAFEGWSPCEEDIVYRLLVPIKAPHGHVFHPELGEEGEVLARNSRIRVELVCMCTREQQLGDVLCFLHHSEEELSQNQQPSLLQTLCTGSYLDVQKTAAWFNKQVPRTWRLTHRAHRYGLKVLPSSRSCKLQVTDTSSGEKVHVELLFGVQQGNLDIFLSSQNAEAVFTPSTTWPQSCAVAERKYFEYVARTAGPNSCHLVCLRLFAHILVGMGFSTYAIKTLLLHLLAIIPLEDWRRRHFLSRLENLLQYLQYCLNDKVLNHFLLGNATMPDEVVLPQAFQTASPLNLFQHLEQDPDAHSRVLRDFKELKDRLFRLLLFGR", "length": 542 }, "evidence": [ { "id": "G3MZM9", "url": "https://omabrowser.org/oma/group/G3MZM9/", "database": "OMA" } ], "glygen_name": "Chicken", "common_name": "Chicken" }, { "uniprot_canonical_ac": "A0A8V0ZD85-1", "protein_name": "Mab-21-like HhH/H2TH-like domain-containing protein", "gene_name": "LOC124418382", "tax_id": 9031, "organism": "Gallus gallus", "sequence": { "sequence": "MALVLVLALLVRALIVSGSDHAVMLERVQQHEKEQRNGEQSWVDMPALLFTLLHYWKIWLCTGLFVFLFWNMWRSLKRKQHEEGGQQEQQEREEQVEEVEPEEQQEQVEQEEQLERVEELERVDQVEHVEQEEREDQGEQVQQEEQVEEVEREDEEDEYFYHSALTRYIARRAWEKMQGRATKCVLVEELMRDLLQTFTFVCPNSFYPVLQPAIGVGSAFEGWSPCEEDIVYHLLVPIKAPHGHVFHPELGEEGDMLARNSRIRVELVCMCTREQQLGDVLCFLHHSQEELSQNQQPSLLQTLCTGSYLDVQKTAAWFNKQVPRIWRLTHRAHRYGLKVLPSSRSCKLQVTDTSSGEKVHVELLFGVQQGNLDIFLSSQNAEAIFTPSTTWPQSCAVAERKYFEYVARTAGPNSCHLVCLRLFAHILVGMGFSTYAIKTLLLHLLAIIPLEDWRRRHFLSRLENLLQYLQYCLNDKLLNHFLLGNATMPDEVVLPQAFQTASPLNLFQHLEQDPDAHSRALRDFKELKDRLFRLLLFGR", "length": 539 }, "evidence": [ { "id": "G3MZM9", "url": "https://omabrowser.org/oma/group/G3MZM9/", "database": "OMA" } ], "glygen_name": "Chicken", "common_name": "Chicken" }, { "uniprot_canonical_ac": "A0A8V0ZE07-1", "protein_name": "LIM domain only 1", "gene_name": "LIMO1", "tax_id": 9031, "organism": "Gallus gallus", "sequence": { "sequence": "MVLDKEDGVPMLSVQPKGKQKGCAGCNRKIKDRYLLKALDKYWHEDCLKCACCDCRLGEVGSTLYTKANLILCRRDYLRLFGTTGNCAACSKLIPAFEMVMRARDNVYHLDCFACQLCNQRDSNPMGWYGSHPVTAAWEAEARTTSLGQPGVRAAELP", "length": 158 }, "evidence": [ { "id": "G3MZM9", "url": "https://omabrowser.org/oma/group/G3MZM9/", "database": "OMA" } ], "glygen_name": "Chicken", "common_name": "Chicken" }, { "uniprot_canonical_ac": "A0A8V0ZGC1-1", "protein_name": "Ig-like domain-containing protein", "gene_name": "LOC124416945", "tax_id": 9031, "organism": "Gallus gallus", "sequence": { "sequence": "MVAGSPALLLLLSLGLCFTGAQGQGNTMAVSFLNRSMKHPKEGQRLGLECHTYKTSWGVSWIRLDKDGNLHFIVYISKFSSTTFPGNKGASSQFEVSKQGSSYRLTVKNFRAQDQGIYFCIANINQVLHFSSGQRAFFPVTTTTAAPTTLRAVTLTATTQSSQVTMKDISQHSPDPGRSKENMPNFCCKLVMWVNLACACLLLLTAITITTTHCQRPSSP", "length": 220 }, "evidence": [ { "id": "G3MZM9", "url": "https://omabrowser.org/oma/group/G3MZM9/", "database": "OMA" } ], "glygen_name": "Chicken", "common_name": "Chicken" }, { "uniprot_canonical_ac": "A0A8V0ZPB4-1", "protein_name": "trypsin", "gene_name": "LOC107049069", "tax_id": 9031, "organism": "Gallus gallus", "sequence": { "sequence": "MKFLVLVAFVGVAVAFPIRDEDDDKIVGGYSCARSAAPYQVSLNSGCHFCGGSLISSQWVLSAAHCYKSSIQVKLGEYNLAAQDGSEQTISSSKVIRHSGYNANTLNNDTMLIKLSKAATLNSYVNTVPLPTSCVTAGTTCLISGWGNTLSSGSLYPDVLQCLNAPVLSSSQCSSAYPGRITSNMICIGYLNGGKDSCQGDSGGPVVCNGQLQGIVSWGFGCAQKGYPGVYTKVCNYVSWIKTTMSSN", "length": 248 }, "evidence": [ { "id": "G3MZM9", "url": "https://omabrowser.org/oma/group/G3MZM9/", "database": "OMA" } ], "glygen_name": "Chicken", "common_name": "Chicken" }, { "uniprot_canonical_ac": "A0A8V1A1Z3-1", "protein_name": "Bridging integrator 2", "gene_name": "BIN2", "tax_id": 9031, "organism": "Gallus gallus", "sequence": { "sequence": "MPSLYHPNAIPVPFPSHPCTTLMSSLTHHIIPVPSSCLPNVIPIPYHPHVISTLSLLHPHFIPMAFLNLPHAIPVPPLIHSCAVPMSYHPFPISFSFPSPSHPSIAPMQSPSYPYPTPVPPPFHLLPIPIPTPVPPPCHSCSIPIQPRCRLHAILVPFPPHCHPHPVPAPSPPHPSAIPMPSHFHPHPIPVPPHTISIPSPPQCHLHAIPVPSPTHPHPIPSHPRFPHPLWAQGHPHPRGSNLSPPIPPPPPNTFALQNEGNKLYKDLKAFVGAVKVMHESSRKVAETLQEIYSTEWDGHVELKAIADSNDLLWDDYEAKLGDQALRLMENYLAQFGDIKERIAKRGRKLVDYDSARHHLEALQNAKKKDEAKIAKAEEEFNRAQAVFEELNRELREELPVLYGSRIACYVTIFQNISNLRDIFYKEMSKLNRDLYEVMGKLDKQHSSKVFIIKGVPSKRRSLLISAPVSPPAAYPCPGKAPNWDPSSGAEQTPTSPRVGSDATEDVPNGLAAPGPAEPGAPMPGPPPASPTSVRSASESESECSEESREIDLSPKEMEVSVGSGCPEYPKTEGAAKGEVEGIAASMASMIVSEAIAAATGAAPGDSDGVGGGDSTDSEISPAEGAWGGPSPGGSEERVEGTDVSPEVGSDAGPCEHGTPEPPQQDVSCDPPQDPSESLTPL", "length": 682 }, "evidence": [ { "id": "G3MZM9", "url": "https://omabrowser.org/oma/group/G3MZM9/", "database": "OMA" } ], "glygen_name": "Chicken", "common_name": "Chicken" }, { "uniprot_canonical_ac": "A0A8V1A7J1-1", "protein_name": "Mitochondrial transcription termination factor 4", "gene_name": "MTERF4", "tax_id": 9031, "organism": "Gallus gallus", "sequence": { "sequence": "MAGRLLGLLRARAPRAVLPAPGPASRHRCGTAGPEEGEAAELLAMGFSQAQARRLRLLRPGLEPQRRAEAAAQLLLLGLSAEAALGLLERSPGLLRMETARLKERAEYLRRLGLEGERGGPLPRGVHAAPAEDGGGGAAAAGAVSVHGRAADRAAAELPRGAAGGAGPRAAPLPGAGRRAGRSGGVAGAARPALSSARLHAQYAYFRMGVRQKEMVKARLFRTPFAELRNRHVFLERRGLYRTPHKGQSQSGNPALRDVLRPTEGDFVAGVARASPDEYEVFKRLLAREEEEMEEEEEEDEEEEEEEEGSAALHAEGGDRDWHSSEPSPIAPCPPAPQ", "length": 338 }, "evidence": [ { "id": "G3MZM9", "url": "https://omabrowser.org/oma/group/G3MZM9/", "database": "OMA" } ], "glygen_name": "Chicken", "common_name": "Chicken" }, { "uniprot_canonical_ac": "A0A8V1AKD9-1", "protein_name": "Borealin", "gene_name": "LOC121107214", "tax_id": 9031, "organism": "Gallus gallus", "sequence": { "sequence": "MAPARRKAAAGARGRKLSAFLKDFDREVRSRVEQLRTNGERLVKEMENLYDVELLRLPAALREMNWLEFFAKGGSQKVVEEAVTADLGITEINKLTAELIQTPLKIVTKEKSKQGIEATEEAAEVPLLPPAKKAKHDSQLLLEQAAASTNPRNGKVRTSTKKAPVSRSRRAPSARVKRVSKRSSKSSFITPATGRNLDLCARGGASIVTPRFDSRVFKTPGLRTPAVNERVYTISANGSPLADGNDVFITVPVGGGESIRLTASDLTKKNLLHLNPEARGIMKKLSVRLAQACSSAKTHR", "length": 300 }, "evidence": [ { "id": "G3MZM9", "url": "https://omabrowser.org/oma/group/G3MZM9/", "database": "OMA" } ], "glygen_name": "Chicken", "common_name": "Chicken" }, { "uniprot_canonical_ac": "A0A8V1AMC7-1", "protein_name": "ODF3A protein", "gene_name": "LOC121107218", "tax_id": 9031, "organism": "Gallus gallus", "sequence": { "sequence": "MPASMDGAWVGTWRPHRPRGLISAQFPSPGPQYSIPGTTGYVGHSPTKARAPAYTFRGTKPPAAGSCGPGPCYFVEPAITRNGKYVAPGAQLRGRPVTKTTVTPGPSDYRTEAANRHVFKCPPVQSMAFRREPLRTDHPPGPGTYTLPRLMGPNTVYTSASPCYSVRGRSQRGRFDEDLAKTPGPAALPKVPVDAYKTRAPAYTMAARPKAGEGKAAKPGPADYSVGRVTLIKPQAPASTFGIRHSLYTTPLIVE", "length": 255 }, "evidence": [ { "id": "G3MZM9", "url": "https://omabrowser.org/oma/group/G3MZM9/", "database": "OMA" } ], "glygen_name": "Chicken", "common_name": "Chicken" }, { "uniprot_canonical_ac": "A0A8W4F7J1-1", "protein_name": "40S ribosomal protein S26", "gene_name": "", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MQPIHCTNCARCMPKDKAIEKFIIRNIVEAAAVGVISEVSVFAAYVLPKLYAKRHYCESCAIHSKVIRNRSREAQKVRTPPPRFRPTGAALRPPPKCM", "length": 98 }, "evidence": [ { "id": "G3MZM9", "url": "https://omabrowser.org/oma/group/G3MZM9/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "A0A8W4F8K9-1", "protein_name": "Olfactory receptor", "gene_name": "LOC110258234", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MRNHTVTTFILLGLTDEPQLKTLVFIFLFLTYMLSVTGNIISLTSTDSHLKTAMYFFLQNFSFLEIAFTSACIPKYLYNIATGDKTITYNSCATQLFFTDLFAVTEFFLLATMSYDRYVAICKPLHYVTIVNHTVCRRLIFGSWLAGLLIIIPPLSLGLKLEFCDSNVIDHFVCDAAPLLKISCSETWLIEQMVIVCAVLTFIMTLMCVVLSYVHILKTILQFPSAQQRKKAFSTCSSHMIMVSISYGSCIFIYVKPSPKDSLAVNKGVTILTTSIAPMLNPFIYTLRNKQVKQAFNDAIKRIALFSKN", "length": 309 }, "evidence": [ { "id": "G3MZM9", "url": "https://omabrowser.org/oma/group/G3MZM9/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "A0A8W4F9E2-1", "protein_name": "UPAR/Ly6 domain-containing protein", "gene_name": "", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "RLEFSSLSPAEVPLVAAAGGRGAFDMRCHECDTKNTFACDHIVTCPRGIRRCLTLSIRLSSREIYVYKGCTRNCTFIYADEQPPPGERKPPRSNSLYFVQCCNAITCNRGGPINLEKDITPPLILEEELGGTVRLGEATLFLSVASVLVSHALT", "length": 154 }, "evidence": [ { "id": "G3MZM9", "url": "https://omabrowser.org/oma/group/G3MZM9/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "A0A8W4FBC5-1", "protein_name": "Olfactory receptor", "gene_name": "", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MLTHSFSFFSSSSSSSTYSSSYPLLPLLLQPQNQFRIWALKDYGQRNSTSLHDFILLGVVATFYLITLVGNTAIILASLLDSHLHTPMYFFLRNLSFLDLCFTTSIVPQMLLYVYMWLGSIECLLLAVMSYDRFTAICKPLHYLVIMNPHLCLKMIIMVWSISLANSVVLCTLTLNLPRCGNNLLDHFLCELPAMLKIACIDTTAVELSVFALGIAIVLTPLILILISYGYIAKAVLRMKSTAGQRKAINTCGSHLTVVSIFYGAIIYLYLQPGNSASKDQGKFLTLFYTIITPSLNPLIYTLRNKDMKEALKKLMRVDHKSTKSKRTWKS", "length": 331 }, "evidence": [ { "id": "G3MZM9", "url": "https://omabrowser.org/oma/group/G3MZM9/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "A0A8W4FBS2-1", "protein_name": "Olfactory receptor", "gene_name": "LOC110258626", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MRNHTAITTFILLGLTEDPQLQLLLFLFLFLTYILSVAGNLTIITLTLLDPHLKTPMYFFLQNFSLLEISFTTACIPRFLYSISTGDRTITYNTCFTQLFLTDLFVITEFFLLATMAYDRYVAICKPLHYMTIMSNKLCKTMVVCCWLAALLIILPPFSLCFHLEFCDSNLIDHFACDASPLLKISCSDTWLIEQMVIACAVLTFIITLVGVVLSYIYIIRTILKFPSAQQRKKAFSTCSSHMIVVSITYGSCIFIYINPSAKEEVNLNKSVSLLISPISPVLNPFIYTLRNKQVKQALHDSLKKTAFLLRK", "length": 312 }, "evidence": [ { "id": "G3MZM9", "url": "https://omabrowser.org/oma/group/G3MZM9/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "A0A8W4FCJ2-1", "protein_name": "Histone H2A", "gene_name": "", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MSRKRNLPQCNPPKKQALSRSSRAELQFPVSRVDRYLREGRYAQRLSSHTPVFLAGVLEYLTANILELAAGEAHSSRKMRIAPEHVQRARSHNETLSSLFQASSVSRGAEEEAEEPLPEAGR", "length": 122 }, "evidence": [ { "id": "G3MZM9", "url": "https://omabrowser.org/oma/group/G3MZM9/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "A0A8W4FD42-1", "protein_name": "Olfactory receptor", "gene_name": "", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MTALNHTGVSHTVFYLLGIPGLEDQHLWISIPFFISYVTALLGNSLLIFIILTRRSLHEPMFLFLCMLAGADLVLSTCTVPQALAIFWFRAGEISLNCCITQLFFIHSIFVFESGLLLVMAFDRYVAICYPLRYTTILTHPLIGKIGVTIVLRSYCAIFPIIFLLKRLTFCRSNVLPHTGCEHIGLAKYACNDIRVNIWYGLFVIVSTLLLDILLIFVSYMLILHAVFHMPSQDARHKALNTCGSHVCIIILFYGPGIFTALTQRFGRHIPAHIHILLANVCILVPPMLNPIIYGIKTKAIQEQVALILFPKYR", "length": 314 }, "evidence": [ { "id": "G3MZM9", "url": "https://omabrowser.org/oma/group/G3MZM9/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "A0A8W4FH98-1", "protein_name": "Uncharacterized protein", "gene_name": "", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "VCHYGNYYSGLSCSCGYGCGYSRCGCNCDYDKCGYRCGYGGYVYGCCHLSCCGRYRPYGFY", "length": 61 }, "evidence": [ { "id": "G3MZM9", "url": "https://omabrowser.org/oma/group/G3MZM9/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "A0A8W4FHY5-1", "protein_name": "Ig-like domain-containing protein", "gene_name": "", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "DTGSCGAIVLTQTPLSLSVSPGEPASISCRSSQSLEEYGKNWLSWYQQKPGQSPRLLIYQATNRASWVPERFSGSGSGTDFTLKISRVEAEDAGVYYCQQYKEFPPTVIQPLTQTPLLGAQLHTWLCVVWGAEGQKL", "length": 137 }, "evidence": [ { "id": "G3MZM9", "url": "https://omabrowser.org/oma/group/G3MZM9/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "A0A8W4FIZ4-1", "protein_name": "Envelope glycoprotein", "gene_name": "", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MRPTLSRRHLPTRGGEPKRLRIPLSFASITWFLTLTITPQASSKRLVDSLTSPKPLSLTWLLTDSSTGITINSTQREAPLGTWWPELHVCLRLVIPGLNTMSTPPDILRAYGFYVCPGPPNNEEYCGNPRDFFCKKWSCVTSNDGYWKWPTSRQDRVTFSFVNSYTSYNQFNYGHGRWKDWQRQTQNRQISCSPSDLDYLKISFTEKGKRENIQKWINGMSWGVVYYRGSWGGEGSILTIRLRIETQMEPPVAVGPNKVLTEQGPPIQGQRPSPNPSDFNTTSG", "length": 284 }, "evidence": [ { "id": "G3MZM9", "url": "https://omabrowser.org/oma/group/G3MZM9/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "A0A8W4FJ61-1", "protein_name": "Uncharacterized protein", "gene_name": "", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MSSTKNKHLMKGSKKGPKKKVADPFSKKDWYDGKAPAMLTKKRNIRKTLVTGTQRTKITSDGLKGHVFSSEPCQSAE", "length": 77 }, "evidence": [ { "id": "G3MZM9", "url": "https://omabrowser.org/oma/group/G3MZM9/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "A0A8W4FJT7-1", "protein_name": "G-protein coupled receptors family 1 profile domain-containing protein", "gene_name": "", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MKNPEVRKIHSAVFLITYLSTILGNLLIVVTMVTSQSLRSPMYFFLTSLSLMYVTYSSVIAPKMIVDSFSETTAISLEGCMAQLFAEHFFGGVGIILIIVMAYDHYVVCCLLLGGAWVGGSIHATIQLLFICQTPFCGPNVIDCFMCDLFTLLKLACMDTHLLGILVILNSGVMCMAIILILITSYVVILCSLKSYSFEGQHKALSTCGSHLIVVVLFFVPCIFLYVMPVATYPIDKAMAVSFTIVAPMLNPLTCTLRNAEVNNAMRKLWMKQNTLCYH", "length": 279 }, "evidence": [ { "id": "G3MZM9", "url": "https://omabrowser.org/oma/group/G3MZM9/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "A0A8W4FKQ6-1", "protein_name": "Large ribosomal subunit protein uL5", "gene_name": "", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MVQDQDEKKNPMWELGIHKLCLNICEGESGNRLTRAAEVLKQLTGQSPVFSKARYTVRSFGIRRNEKIAVHCTVRGAKAEEIFERHLRVREYKVQEHISLGTKYDPSIGIYSLDFYVVLGRPGFSFADKKHRTGCIGAKHGISKEDAMSWFQQKYDEIILPGK", "length": 163 }, "evidence": [ { "id": "G3MZM9", "url": "https://omabrowser.org/oma/group/G3MZM9/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "A0A8W4FKY3-1", "protein_name": "Large ribosomal subunit protein eL27", "gene_name": "", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MGKFVKPGKVVLVLAGRYSGRKAVIVKNTDDGTSDQPYSHALVAGIDRYPRKVTAAMGKKKIAKSSKIQSFVKYSVDIPLHKTVVNKDVFRDPALKRKARREAKVKFEERYKTGKNKCFFQKLRF", "length": 125 }, "evidence": [ { "id": "G3MZM9", "url": "https://omabrowser.org/oma/group/G3MZM9/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "A0A8W4FLM5-1", "protein_name": "Small ribosomal subunit protein uS14", "gene_name": "", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MGHQQLYWSHLRKFGQGSRSCCVCSNWHGLIRKYSLDMCHQRFCQHMKDPGFIRLD", "length": 56 }, "evidence": [ { "id": "G3MZM9", "url": "https://omabrowser.org/oma/group/G3MZM9/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "A0A8W4FNC8-1", "protein_name": "Olfactory receptor", "gene_name": "", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MGQRNQTSSLADFILEGLFDDSPAHAFLFSLTMVVFLIAVSGNTLTILLICADPRLHTPMYVLLTNYLSGTKSISFVGCATQYFLFLSLGCAECILLTFMSYDRYVAICHPLRYAVLMNRKVGQMMAVMSWLGASVNSLIHTVILMHFPFCGHRNIHHFYCEFPAVVQLVCGDITVYEIAVYIGDIVLLLLPIALISASYVFILHSVIRMHSAGGKRNAFATCSSHLTVVSLWFGACIFSYMRPRSQRTPLQDKVGSVFYTIITPTLNPLIYTLRNKDIAKALKRVLGREMITQNPKVRLP", "length": 301 }, "evidence": [ { "id": "G3MZM9", "url": "https://omabrowser.org/oma/group/G3MZM9/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "A0A8W4FP10-1", "protein_name": "Ribosomal protein L19", "gene_name": "", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MSVLRLQKRLASSVLRCGKKKVWLDPDETREIANAKSRQQIWKLIKDGLSIQKPGTVHSRARCQKNTLRKGTASAGMPKKSVPERDGNVFKNKRILMEHTHQLKADKARKKLLADQPEARRSKTKEARKRRQERLQAKKEERNRTEVETKFCRLI", "length": 155 }, "evidence": [ { "id": "G3MZM9", "url": "https://omabrowser.org/oma/group/G3MZM9/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "A0A8W4FP36-1", "protein_name": "Small ribosomal subunit protein eS24", "gene_name": "", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MQDTASIRTRKFRTNQLLPGKQRVIRVLHPGKATVPKTEIWGKLAKMNKRTPDVIFVFGFRTHFGGGKTTGFGMSHDSLDDYTKTNEPKHKRARHGLYEKSKTSRKQRKERKNRMKKVGGTAKANAGAGQKGGV", "length": 134 }, "evidence": [ { "id": "G3MZM9", "url": "https://omabrowser.org/oma/group/G3MZM9/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "A0A8W4FQE1-1", "protein_name": "Olfactory receptor", "gene_name": "", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MTALNHTGVSHTVFYLLGIPGLEDQHLWISIPFFISYVTALLGNSLLIFLILTRRSLHEPMFLFLCMLAGADLVLSTCTVPQALAIFWFRAGEISLDRCITQLFFIHSIFIFESGLLLVMAFDRYVAICYPLRYTTILTHTLIGKIGVTIVLRSYCAIFPIIFLLKRLTFCRSNVLPHTGCEHIGLAKYACNDIRVNIWYGLFVIVSTLFLDVLLIFVSYMLILHAVFHMPSQDARHKALNTCGSHVSVIILFYGPGFFTTLTQRFGRHIPAHIHILLANVCVLVPPMLNPIIYGIKTKAIREQVAHLLFPKQK", "length": 314 }, "evidence": [ { "id": "G3MZM9", "url": "https://omabrowser.org/oma/group/G3MZM9/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "A0A9J7F7T0-1", "protein_name": "Protein transport protein Sec61 subunit gamma", "gene_name": "LOC100757015", "tax_id": 10029, "organism": "Cricetulus griseus", "sequence": { "sequence": "MDYVMQFVEPSGQFVKDSIWLVKRCTKLDRKEFQKVAMSTAMVFAIMGFTGFVKLIHIPVNNIIVGG", "length": 67 }, "evidence": [ { "id": "G3MZM9", "url": "https://omabrowser.org/oma/group/G3MZM9/", "database": "OMA" } ], "glygen_name": "Hamster", "common_name": "Chinese hamster" }, { "uniprot_canonical_ac": "A0A9J7GY23-1", "protein_name": "Tetratricopeptide repeat protein 16 isoform X2", "gene_name": "Ttc16", "tax_id": 10029, "organism": "Cricetulus griseus", "sequence": { "sequence": "MTDSSTEESVNVQTQKIPKLQVPETRETTLQRIFGTSQVFYSVSGVVKPRLTESTVPFRVREYYHQGHHCLEQEDWEMAVLYFSRALHLNPDQVEFYIFRAEAFIQLCDFSSALQNLRRAYSYEPENSKYLERLAFVLYLQGQCLYELCDFQEALYVFLQASDLQPQNPSFSYRCMACLLALNRHQDCLSLVTREVKQGRATADVYILRARIYNFFQKPKLCYQDLRSALLFNPKHPQAKGLLQVMVDQAKKSLQDASILAVQGKLHRALKRISCAIENNPLDPNLFLFRGTLHRRLQQFDPAVEDFLKAMDMVTDSQDNLVQKTQRQLLLTYNDFAVHCYTQGAYQEGVLLLNKAIRDEQNEKGLYINRGDCFFQLGNLAFAEADYKQALELCPKDEGANLRMGVLQEKMGLCEQTRRQFQKAEDHFSAAIKYNPVNAQYYLHRAKNRQLLQNIVGACQDIATVLLLNPKYPKMAPLMAKLFPGMSVEEVLNSHVAQLAKLQLRRMIESGPKASHPQSIVAKRLIERQKAQALMESWNWEQLFTRNPEEEVAPSESLQGKTLREKIEFKREVVEEKKVKILRKVTSLSDSYVDQTSSGSEFSILSPSTLETEVSTMEYKSTSNTAASSAERLLPQYLVTTKYKESLGLSMAPNVTQVSEDLHKSLTENIPDDGPRHHSSKAEATQRPKPRKTEPSQSLGKQRPSQRPSITEATKGPKPRKNRPALSPRQRLRRAKAVQAQNWKPRTNSNSQKTSSLLSNIAVIISSSNEAQDQSPVPSKADDISSYNDSTATSSTNTDSLRLSIHLSKPKYSKDQSPSHNKEEVSPTSNNYAAP", "length": 835 }, "evidence": [ { "id": "G3MZM9", "url": "https://omabrowser.org/oma/group/G3MZM9/", "database": "OMA" } ], "glygen_name": "Hamster", "common_name": "Chinese hamster" }, { "uniprot_canonical_ac": "A0A9J7GZF8-1", "protein_name": "Protein EURL homolog isoform X2", "gene_name": "C4H21orf91", "tax_id": 10029, "organism": "Cricetulus griseus", "sequence": { "sequence": "MIIKRKATVIHHKGTMNEEEQFVNIDLNDDNICSVCKLGTDKETLSFCHICFELNLEGVPKSNLLHTRSLRGHKDCFEKYHLIANQDCSRSKLSKSTYEGVKTLLTKKINWIVQYAQNKDMDLDSECSKNTRHHLFNFRHKPDKKLLPQFDSQVPKYSVKGIAGSTGGLSSYTQRILEQRENTDFGLAILQDSDALWPHKHNQAQKKEETSSGPENVQTQNPRYSREELNSMTLDEVEQLNTKLQQQIQEVFEELTHQVQEKDSLASELHVRHVAIEQLLKNYSKLPCLQVGRAGPRSHLPINN", "length": 304 }, "evidence": [ { "id": "G3MZM9", "url": "https://omabrowser.org/oma/group/G3MZM9/", "database": "OMA" } ], "glygen_name": "Hamster", "common_name": "Chinese hamster" }, { "uniprot_canonical_ac": "A0A9J7JMJ4-1", "protein_name": "Olfactory receptor", "gene_name": "LOC100771730", "tax_id": 10029, "organism": "Cricetulus griseus", "sequence": { "sequence": "MDFVNISLVTEFFLVGLTDQPELQMPLFFLFLAVYLITALGNLCLIILTVLNSNLHTPMYFFLFNLSFIDICYCSVFTPQMLMNFILRENIISYMECMAQVFFFCFFVVSECYVLTSMAYDRYMAIYNPLLYNVVMSPNLCLNLMFGSYFIGFSNAVAHTVCMLRLTFCDTNIINHYFCDIPPLLQLSCTSTYVNKLVIFVFASINIIVPTSTILVSYGFILSSIFHISSSEGRSKAFSTCSSHIIAVSLFFGSGALVYFKPSSAVYMNEGKISSVFYTNVVPMLNPLIYSLRNKDIKVALMKSLNSRNL", "length": 310 }, "evidence": [ { "id": "G3MZM9", "url": "https://omabrowser.org/oma/group/G3MZM9/", "database": "OMA" } ], "glygen_name": "Hamster", "common_name": "Chinese hamster" }, { "uniprot_canonical_ac": "A0AA74KSW7-1", "protein_name": "Predicted gene 3002", "gene_name": "Gm3002", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MLNSSKLGVWAAGVPPSSPTLLFRRWVMKVESLISQPMTSGKNELQDHLIFISEKALHKRLFQKENGDEGVTRPTEKEEGILSHEKGRRKWLWRRHRSARNTSTQNSKMTKKRSKINELEELKLDMRKISNDMEEMCGILNLYMYEDLNYRMNTEFNIIKSQHEKTMLDMNKMIQSIIGSMQYSKELIEDNYSYSIKEDHLLRECTQLHENVRILLNENRRLLVEQAGHKCPVGKKRGSLRRPARTSVSQVPRNTSPAESRTWHRPGHDLPQREVLEEEH", "length": 280 }, "evidence": [ { "id": "G3MZM9", "url": "https://omabrowser.org/oma/group/G3MZM9/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "A0AAA9RU54-1", "protein_name": "Small integral membrane protein 17", "gene_name": "SMIM17", "tax_id": 9913, "organism": "Bos taurus", "sequence": { "sequence": "MQSLRPEQVRGLLEPERAKTLLPRENKAWEKRAAFAKDWVAVEVGASGCGSDEKDLPSPKTLVPQEWSSVEEDDESEDSQPHWAAALPTSPSCPSQDTGTGSGADLCLQCSSPRTPPWLPWAFSHTIESALPTPPRAWLWSLL", "length": 143 }, "evidence": [ { "id": "G3MZM9", "url": "https://omabrowser.org/oma/group/G3MZM9/", "database": "OMA" } ], "glygen_name": "Bovine", "common_name": "Bovine" }, { "uniprot_canonical_ac": "A0AAA9RY85-1", "protein_name": "Core Histone H2A/H2B/H3 domain-containing protein", "gene_name": "", "tax_id": 9913, "organism": "Bos taurus", "sequence": { "sequence": "MNMPEPAKSAPAPKKGSKKAVTKAQKKDSKKRKRSRKESYSVYVYKVLKQVHPDTGISSKALGIMNSFLNDIFERITGKTSRLVHYNKRSTITSREIQTTVRLLLPGELAKHAESEGTKAVTSIPALSKYNMPSRC", "length": 136 }, "evidence": [ { "id": "G3MZM9", "url": "https://omabrowser.org/oma/group/G3MZM9/", "database": "OMA" } ], "glygen_name": "Bovine", "common_name": "Bovine" }, { "uniprot_canonical_ac": "A0ABK0KVZ2-1", "protein_name": "Eukaryotic translation initiation factor 1", "gene_name": "Eif1", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "EFGFRSVASAGWGAACPLGLRHVISCGGRAGLEQKARALSSSSTGLFPEGQQRAPPDFSDDICTDKKKNQERGINKWPTTTRNKNYFFVDPFADASKGDDLLPAGTEDYIHIRIQQRNGRKTLTTVQGIADDYDKKKLVKAFKKKFACNGTVIEHPEYGEVIQLQGDQRKNICQFLIEIGLAKDDQLKVHGF", "length": 192 }, "evidence": [ { "id": "G3MZM9", "url": "https://omabrowser.org/oma/group/G3MZM9/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "A0ABK0L002-1", "protein_name": "Oocyte specific homeobox 2 like 1", "gene_name": "Obox2l1", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "ILQSVQNTDMIEGPSFLPKFQMSSYTPMDTSSQLPQEPSWNLAFQMGQSPLVTSRTPMQSSPSVPEQNLNWQESQGSSRESSIQMQPGPVMDPGFPTLRSPSGHPSHQRPSRPSSRSGFHVPIEPMALSDKHGGKQTGPVAPRKCRKERTQYSAKQKSVLQEHFAECQYPDKKLCLELATLFGVTENEIKVWFKNNRAKCKQKNVPEALPETNGGPEAVSWSTDFPGSIAVVGCDQGEPMATAILDVDSTPKLNCSQESSLDGNWTYDGAMCCLPEDVLDGNDPVTAGDSGESAPVEAQSDLAAAGAPVAMAVDTQNPEECEDLPLLDEGVWQWMLEDFHQLEDWFTKNYIESPSSASHPLD", "length": 362 }, "evidence": [ { "id": "G3MZM9", "url": "https://omabrowser.org/oma/group/G3MZM9/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "A0ABK0LHI6-1", "protein_name": "CD27 antigen", "gene_name": "Cd27", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MAWPPLYWLCMLGTLVGLLATPAPNNCPDRHYWIGAGLCCQMCGPGTFLVKHCDQDRAAAQCDPCIPGTSFSPDYHTRPHCESCRHCNSGFLIRNCTVTANAECTCSKGWQCRDQECTECDPPLNPALTSQPSEAPSPQLPPPTHLPYATEKPSWPPQRQLPDSTVYSRLPSQRPLCSSDCIRIFVTFSSMLLVFVLGGILFFHQRRNHGPNEDSQAVPEELCPYSCPREEEGSVIPIQEDYRKPEPASYP", "length": 251 }, "evidence": [ { "id": "G3MZM9", "url": "https://omabrowser.org/oma/group/G3MZM9/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "A0ABK0LYA6-1", "protein_name": "Prostate and testis expressed 2", "gene_name": "Pate2", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MLSCLTSELQGSACLCLPSTGSYKHILQHLDLGTMCYKCKKYHLGLCYGLMRSCTLKHRQSCAAENFYILTNRGQSMYHYSRLSCMTNCEDINFLSFERRTELICCKHSSYCNLPMGL", "length": 118 }, "evidence": [ { "id": "G3MZM9", "url": "https://omabrowser.org/oma/group/G3MZM9/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "A0ABK0M6C3-1", "protein_name": "Prohibitin", "gene_name": "AABR07037878.1", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MYNKNIKNSISISVCVGGVGGVRARAHAHAHTSPHACTRVIHAFVMLEVGPRDFVHIKKAFRGIDVKKPVIFDCRSQPRNVPVVTGSKDLQNVNITLRILFRPVTSQLPRIYTSIGLDYAERVLPSITSEILKSVVARFNAEELITQRELVSKQVSDDLTERAATFGLILDDVSLTHLTFGKEFTEAVEAKQVAQQEAETARFVVEKAEHQKAAAIISAEGDAKAAELIANSLATAGDGLIELRKLEAAEDIAYQLSSSQNITYLPVGPSSVGPSVRQSMFLRLPQ", "length": 286 }, "evidence": [ { "id": "G3MZM9", "url": "https://omabrowser.org/oma/group/G3MZM9/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "A0AC58FXL6-1", "protein_name": "Cytochrome P450 2X10.2 isoform X2", "gene_name": "cyp2x10.2", "tax_id": 7955, "organism": "Danio rerio", "sequence": { "sequence": "MSDLRGIYSYMLSTVNSLVRDSSLTNFKKEFCVHAYLLSVCIQYQSSVWSSSRSVTMLTALVLLCLGAFLLYLQLRIRRPKNFPPGPAPVPIFGNLLQLNRISPLKDFDKFAQHYGSIYGIYIGSQPAVVLTGQKMIKEALITQAAEFSGRSNNMMFSHVTGGKGVIMADYGESWREHRRFALTTLRNFGLGKKSMEQRILEEVKHICLLLEESAGKSIDPQHLYHQAASNIIASVIFGSRFNYKDAYFQTLITSVEDLTKITIGPWAMLYEIAPVLRIFPLPFQKAFQYFEQITKHVLKVVEEHKTSRVAGEPRDLIDCYLEEMENKSDHRTSFDESQMVTLLFDLFIAGTETTSNTLRTLTLYLMTYTHIQEQCQREIDEVLGARDHVTYEDRNAMHFVQAVIHEGQRVADIAPLSMFHSAKTDTQLRGYSIPKGTIIIPYLSSSLREEGQWKFPHEFNPQNFLNEKGEFVKNDAFMPFSAGPRVCLGENLARMELFLILVTVLRRFRLVWPKDAGEPDFTYIYGGTQSVKPYRVIVEPRMHGEACKFVD", "length": 552 }, "evidence": [ { "id": "G3MZM9", "url": "https://omabrowser.org/oma/group/G3MZM9/", "database": "OMA" } ], "glygen_name": "Zebrafish", "common_name": "Zebrafish" }, { "uniprot_canonical_ac": "A0AC58J797-1", "protein_name": "Uncharacterized protein isoform X1", "gene_name": "si:dkey-233e3.2", "tax_id": 7955, "organism": "Danio rerio", "sequence": { "sequence": "MANAKQLLKNSLDELVEAELKEFQWYLINDHRDISKAEMEKADRLKTVDKMVSCFGPKGAVKTTVDILRKINQNELAEELENKHKQGNCMSARAEGAVLETCKSPPFDYTNTSRELKKKLKEDYEKILVGNSQTGHKKYLEDIYTDLYVVENETGGRERQHEVIQMESKHNQQDRPLKCNDMFKVQPDTGRKHRRILTLGIAGVGKTVSVNKFILDWAEGKDNQEIVFIFPLPFRRLNLIKEEKYSLIGLLNKYFFSISGGLSSLPEKQGKVMFIFDGLDEYRFKLNFKKDDGFTDVNKEMTVSEIITNLLKRHLVPSSLMWITSRPAASSLIPRDLIDQVTEVRGFIDEQKEHYFIKNSSPEVARNIIGHIKKSRSLYIMCHIPVFCLISLTVLQPLLGQESNEKTPTTLTGMYINFLLSQKQQMKEKYRNDTESEANACSFDEIVLKLGKLAFKQLQKGQLIFYKTDLEKCGLDVRQGSVFSGLCTRMFQEENHYSGEQVYSFVHLSVQEFIAALYVFFTYKNKKANLFLDSWKKELKWKLSEKPLFKLHTAAVKKTLQSKNGHLDLFLRFLMGLSLESNQSDMKELLPWLKLKTGMIKDTTDYIKKKIEEENSAERTINLFHCLNELNDDFVEELQKSLCSGNLTAQDLSSAQWSGLVFVLLMSEETQEKFELQKYRRSDEALMRLIPVVKNTTRALLQCCNLTAQSCESLSSALQSSNCVLRELDLSNNDLQDSGVNLLSNGLKSPKCKLEILRLSGCMVTEEGCGFLSSALTSNPSHLRELDLSYNHPGDSGLKLLSQKLEDPNYTLNKLNLDHGGEKWFTAGLHKYACFLTLAPNTAHIELRLSEENRRVTRVGERQQYPDHPDRFDHHAHVLCRESVCGRCYWEIEMNAGDRVDIAVSYKSIKRKGRGYECVLGQNAQSWALICYVNRVAFRHNMIETRLPVKLMSRRIGVFVDHSAGTLIFHNIYRDSMSLIHSVQTTFTEPLYPGFWVEYGSSVKLC", "length": 1006 }, "evidence": [ { "id": "G3MZM9", "url": "https://omabrowser.org/oma/group/G3MZM9/", "database": "OMA" } ], "glygen_name": "Zebrafish", "common_name": "Zebrafish" }, { "uniprot_canonical_ac": "A0AC58JHM1-1", "protein_name": "Phoenix isoform X1", "gene_name": "pho", "tax_id": 7955, "organism": "Danio rerio", "sequence": { "sequence": "MDLRSKGDTSVGEVMEADPRAELIFETPPPDVVSSINACFEEIDSALKIRRDPSVHSPPSDSDSESLFITQSVTKVVHTKRRLRSSKKPDSISDDSGYVRERRLSENQQTECEEESRSLRSSRRKRSKWEMYASARKATFPFLMKSLKTQHLPIRKHQILENSEVGGFFKCIKKIKTGSVKMGKVISSHLFQSPISDSSEEEDQNSEHDVISVDKALFVPGYKRGINFKWLPDFIRERRTLENYLSNGVDKEKKTEQIIEYRQRNQHPQRTSAKALSKSSQVSKKPKKQDTHEVLASCSDHEDLEIAECAENSHEGHKVVIEETQRQTVEEASAHLEHEDDLNCKVVEYRKRKRHPKRTSAKALSKSSQVSKKPKKQDTHEVLASCSDHEDIESVECAENSHEDHNVVIEETQRQTVEEASAHLEHEDDLNCKNQPDVDQPNESNFIGPPQEGDISTQSDTQQTDSDIGSVDLFSPLNSPKRDDQIPNTTSITANVEENDQDSDVTQIESEGQHVSTFTQETQKCFANEEYDSDETHIDTESLSRFKPRTPNKQFTSTKHPEIPQFRVQSPKPPSRQAETVNVQLSPKHLPLSNVPLSEVPISPCESAIVGRQKTMVETETDSPMFKITGPSFLKRKRKRTKDKNAAADFKQHDTNGDVGQMVSCPGDDITGLKAVPIENIEACGVEHEMAIGEQTEELGLKSKELLEESVLSTVNSVSTKSKREKMKKYKVKECEAVENQLVETSKKAKKKKKDKERIATSYPEENNLTNIQSNEGFDSAELRVKEVNQSSQSLNTDQPTCVQTSEEITGETELKKKTTRHETDDPLYESVGLDVTLASQFDVGLRIDEQQEGLVTEEAERDERLQGKAMKVAKGKKKIQDTSFQVDHDIGLDKQRSDSGAKPANLDLDGLESLTIKKKKKKKKKHKLKEKTDPKLDFDFDHNVQFFQTDRLQTTDSVLLDSTHTNKQKKKKLKCQNDTDQSSDLKQLHVVGSKLQTIDLPKTDKHMERTGVSSSDALLEHMDDRTLGMRENNTIQTDQIEHLQTSEEVTRCSSPRLSSDKKREKTSVHPNLDASSVFQFDGFKANEDQAITQNTTKEKQISSEQLENNLVGPPSQVENIANVNSSVLLDHTHMNTLREGQLKEQTYKELALAFGLKQLCIVVNKLKTTDLPKTNKNMEGTGVGSSDELLKHTDDRTLETRENNTIQTNQIEHLQTSEKVERHSSPRVTRLSFAKKWMKTSVDSNLDASSGSQFDGLNSMAKEDWTFSQNMDLPLKRTKNKQKDKERTGVSSDALLKRMDDRPPEMRKKNTIQTNQIEYLQTSEKVTRRSSPRLTRLSLAKKMEKTSVDPNLDASSGSQFDGLKEASKEDRTAPRNSIEEKQSDAISSEGLENNPAHLVSTNKSDNTSPSSQVDNIVGLQSDANSVLLDHTHTDKQKKKKIKHKLIEQTEKELTSEVEDNVQPFQFIELRAMDLPSKRITNKKLKDRKRTGVSSSDAVLKHIDDGPSDMRENNSIQTDKIEHLQTSEEMTRCPSPRLSSDKKRKKKYVDTNLDASSGFQFNWSNGMAKEYSKNSTNISSLDNMHTSKQKKKKKQKLKEQKNVESVGDNVYSLEPDQFSGLQITEIKTKKKDKKRTKQANVEENDLKGILSNKAFKASQTYQLEHIQTSEEIKGRSPNAASKSAKKKKKKKNETKNPQYESVNLDLSLAKEDRTTTQNHTEETQGDGNAVEHLEMNPAGLIKVSKKKKKRENAGIVQLDNIIGLQSGSSTDVKSSVLSDSTDTNKHKKKKRKTLKEQENVEAEGDDVQSVEPDPFSGLQITEMTTKKKRKHKRCEEQRCLRGVSSHEAFKAPPTNLLQHIQTSEEISQCQSPNVAALENGGSPYQLENITEMQPGNSIDINSSEILYSTCTHKQKWKKLKQQENVEADANDVHSAELNLFSELKISEPTTKKKKHKKCVEKCALKDISSNEGIKAPQTSQLEHVQTSKEITQCQSPNAATLKSEKKKKQKRDETEVPQYLDASSVSQFDDVTRLKKQAKVDRTTTQNSSEETQNDDISSKQLEMNPAHLIKVSKRKKKREKAGSPYKVDKIVGLQSGNFTDVNFSQLSDSKRTDKQKKKKKIKLKEQENAEADVDDVHSVELDQFSGLQITKPTTKKKRKHKRCVEESGLRDISSNEAYKAPQTNQLEHIQTSEEITPFQAPNVAALKSAKKKKKKRDKTVEPQCLDASSVSQFDDVKTRAKEDQTLTPNSSKETQGDDSAVECLETNPAGLMKVSKKKKKRENAASPYKVDNIVGLESGNSADVSSSVPSDSTDTNKHKKKKRKKLKKQEIVEADLQTSEEIIQCQSPNVATLKSVKKKKDETKEHQRLDVSSVSQFDDVSRLKKRAKEDRTTIQNSSEETQSADISSEQLEINPAHLIKVSKRKKKRENGRSPSQVGNIVGLQSGNFTDISSSVLSDSTRTDKQKSKQKKKLKEQENVEADANDFHSAEPDQFSGLQITEMTTKKKKKHKRCVEESGLRDISSNYAFKAPQTNQLEHVQTSEEITQCQSPNVAALKSEKKKKNKRDKTDKPQYLDESSVSQFDDVKKRAKADRTTTHNSSEETQKDNISSECLELNPAHLMKISKRKRENKSLGLLSENTADLNSSSLLDGTDTDKHKKKKRKKLEGQENVEADVDDVHSAEPDQFSELQIPEMTTKKKKKHKRCVEESGLKDISSNEALKALQTNQLEHIETSEEMTIKTVKKEKKKRDATEEPHYKSVDLDVSPTESTTEAKLNPTKHKKKRKQSFSGSHDAHEAPERKRKKDRN", "length": 2809 }, "evidence": [ { "id": "G3MZM9", "url": "https://omabrowser.org/oma/group/G3MZM9/", "database": "OMA" } ], "glygen_name": "Zebrafish", "common_name": "Zebrafish" }, { "uniprot_canonical_ac": "A0MGZ5-1", "protein_name": "Heparan-sulfate 6-O-sulfotransferase 1-B", "gene_name": "hs6st1b", "tax_id": 7955, "organism": "Danio rerio", "sequence": { "sequence": "MNDTERNMVERTSKFLLIVVGSVFFMLILYQYVAPGVINFGSPHGYLLGEEDMTIFPTPDPHYVKKYYFPIKDLERKIDFEIKGEDVIVFLHIQKTGGTTFGRHLVQNVRLELPCDCRPGQKKCTCYRPNRKETWLFSRFSTGWSCGLHADWTELTNCVPGVLNKRESKSKKMRKFYYITLLRDPVSRYLSEWRHVQRGATWKTSLHMCDGRTPTPEELPPCYEGTDWSGCTLQQFMDCPYNLANNRQVRMLADLSLVGCYNLSTVPEKRRSQLLLESAKKNLRDMAFYGLTEFQRKTQYLFERTFHLKFIRPFMQYNSTRAAGVDLDNDTIQRIEELNDLDMKLYDYAKDLFQQRYQYKHMLDRREQRLLRGHASFHSPFREDGAGGEGTARLPTEDYMNHIINGW", "length": 407 }, "evidence": [ { "id": "G3MZM9", "url": "https://omabrowser.org/oma/group/G3MZM9/", "database": "OMA" } ], "glygen_name": "Zebrafish", "common_name": "Zebrafish" }, { "uniprot_canonical_ac": "A1EC97-1", "protein_name": "Dual specificity phosphatase 14", "gene_name": "Dusp14", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MSSRGHSTLPRTLMAPRMISEGDIGGIAQITSSLFLGRASVASNRHLLQARGITCVVNATIEIPNFNWPQFEYVKVPLADIPHAPIRLYFDTVADKIHSVSKKHGATLVHCAAGVSRSATLCIAYLMKFHNLCLLEAYNWVKARRPVIRPNLGFWRQLIDYESQLFGKSSVKMVQTPYGIIPDVYEKESRHLMPYWGI", "length": 198 }, "evidence": [ { "id": "G3MZM9", "url": "https://omabrowser.org/oma/group/G3MZM9/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "A1XQX2-1", "protein_name": "Neurexin-1b", "gene_name": "nrxn1b", "tax_id": 7955, "organism": "Danio rerio", "sequence": { "sequence": "MMILHLGAHLLFIGLIVCKANAGSSLRFTGSDEQWVAFPMWNACCESEMSFSVKTTHLNGLLVYFDDEGFCDFLELHVHVGKLRLCFSIFCAESTCVLSDVAINDNRWHSVSIMRNFRNTTLIVDDEVKWEEVKSKRRDMTVFSHLFLGGIPSELRSVSLQLTSKTVKDHTSFTGWIMDVKVNDSEPAIISSAGVHEDLCGSENTCLNGGVCSVVEDKPTCDCSQTGYQGKDCSEGLAHLMMLDRGMEEYVATFRGSEYFCYDLSLNPIQSSSDEITLSFRTLQRNGLMLHTGKIADYVNLALKNGAVSLVINLGSGAFEALVEPVNGKFNDNEWHDVKVLRNLRQHSGVGYAMVTISVDGILTTTGYTQEEYTMLGSDDFLYVGGSPSTADLPGSPVSNNFMGCLREVVYKNNDAELELSRLAYQGDPKLQIHGVVAFKCESVATLDAITFETPESFLTLPKWNAKKSGSISFDFRTTEPNGLLLFSCGRAKQHNKEAKSPVTLKVDFFAIEMLDGLLYLLLDMGSGTTKTLALNKKVNDGEWYHVDFQRDGKSGTISINSVRTPYLCPGDSELLDLDDPLYLGGVPESSSGTVFPTGAWSALLNYGYVGCVRDLFIDGRSVDVRRAAELQRAAGVKPSCGKEPSGKCVSEPCLNRGVCREGWSRYICDCTGTGFLGHSCERDATILSFDGSKFLKVQFSAAMHTEAEDVSLRFRSLRAYGVLMASTSTHTTDTLRLELEAGRVRLTVNLDCNRINCTTSKGPESLFAGQNLNDDEWHTVRVIRRGKSLKLSVDDLPTVDGEIPGDHTQLEFHNIETGIITGKRQLPTMPSNFIGHLQSLMFNGKPYIDLCKNGDIDYCQTNAPIGFKSIIADPVTFKSCSSYVTLPSLQAYYYMYLFFQFKTTSADGLILYNSGDGNDFIAVELVKGYLHYISDLGNGAHLIKGNSIKPLNDNHWHNVMISRDPNNLHTVRIDTKTTSQTTLGAKNLDLKGDLFVGGVPEQMYKDLPKLVHAKEGFQGCLASVDLNGRLPDLMTEALVCIGQIERGCEGPSSSCEEDSCANQGVCLQQWENFTCDCSMTTYAGPLCADPGSTYVFGRQGGVITYSWPPHDRPSTRVDRLALGFITLMEDATLVRVDSSAGLGDYLKLHIVKGNVVAVFNVGTYDINIEENGKLVNDGNYHIVRLTRSGGNATLQVDDLPVIERFPPGHIDSHRLGTGRLPYRRLVEESLPKNGRQLTIFNSQMTIRIGGWQKQQVSGFQGQMSGFYYNGLKVFSMAADGDPNVRMEGSVRLVGELQSSSTPHGGATVYQSSVTEISSTTSNTITITYSTPADEQQTTDELLVASAECPSDDEDIDPCEPSSGTLCCFVPPAGPTGPAISSFPGPAEVFRESNGTTGMVVGIVAGAALCILILLYAMYKYRNRDEGSYHVDESRNYICNSNGAALKEKNTADDDSGSKSKKNKNKEYYV", "length": 1470 }, "evidence": [ { "id": "G3MZM9", "url": "https://omabrowser.org/oma/group/G3MZM9/", "database": "OMA" } ], "glygen_name": "Zebrafish", "common_name": "Zebrafish" }, { "uniprot_canonical_ac": "A2A7I1-1", "protein_name": "Zinc finger protein 978", "gene_name": "Zfp978", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MFAPHQESGRRTTKRMSASLENTAQCLLTFKDVFLDFSSEEWECLNFAQRTLYMDVMLENYNNLLFVENHCICGNYEKEKVVEQDTQHIFNEHGHIQEKSFKCNESSNIIHESSESTPHKTNHRDATLQSSNLKRHKTGTTKQVCTYKDCVNCLKGSSIISLNQGTHVEKKEHNRNKNLDEVLVSKHKPIVRQNNSEMNTYTCGEFDKCFTQSDNLQSQQRIYPGKKSYKYSESDKCFTQPSHLSIHHTIHSGEKPYKCSECDKCFTDKCTLRKHQRIHTGEKPYKCNECDKCFTDKGSLRVHQRIHTGEKPYKCSECDKCFTQTSHLSIHRRIH", "length": 335 }, "evidence": [ { "id": "G3MZM9", "url": "https://omabrowser.org/oma/group/G3MZM9/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "A2A8N2-1", "protein_name": "PRAME like 25", "gene_name": "Pramel25", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MVICGHCPDQDESLEEVTEECYSPPTLQNLAIQSLLRDEALAISALTDLPQSLFPVIFEEAFTDGHIGILKAMIPEWPFPYLSLGKQINNCNLETLKAILEGLDILLAQKVQTSRCKLRVINWRDHDLNLWAGSHEGEGLSEFTTEKQPIENSPGCEVKKELKVMTEVLRMKGRLDESTTYLLQWAQQRTDSINLFCRKLVIEGLTKASVIEIFKTVHADCIQELILRRICIEELAFLNPYLKLMKRLFTLTLDHIIGTFSFGDSEKLDEEIIFSLISQLPTLHCLQKLYVNDVPFIKGNLKEYLRCLKKPLETLCISNCDLSQSDLDYLPYCLNICELKHLHLSDICLRDLLLEPLGFLLERVGDTLKILELESCCIVDFQFSALLPALSQCSHLREVTFYDNNFSLPFLKQLLHHTALLSQLISECYPAPLECYDDSGVILTHRLESFCPELLDILKAKRQLQSVSFETTQCSKCGGCYIYDQETQCCHFVELLLA", "length": 498 }, "evidence": [ { "id": "G3MZM9", "url": "https://omabrowser.org/oma/group/G3MZM9/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "A2A9Q9-1", "protein_name": "MAGE family member B5B", "gene_name": "Mageb5b", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MPRGQKNKHHRNRLKNKKHNQEKVHPQKDESQEKGHHKRDDFQDHKEARDNAAVEEKSSCSSPSVPGETLEKPPASKTSSDAGWLSCVSSPATVCGDELEFDDGTYFHCGGNSLYSEYRTCQENPCKHCLDMYVNLVEQYVLYKFKMKKLIDRNKLIDLIEPKYRYNFSDIFKRAFENIEIVFAASVIEIDSTNHVYDLVSKLKLPNKGRVCPGRGLPKTGLLMTILAMIFMNGTSASEEDIWKFLNYMQVYPGRKHFIYREPRKLITQDFVKLKYLEYKQISLSDPPCYRFQWGPKAYTETTKMKVLEFMAKGSGVEPSTFSVQYTEALREENQKTKIRKWYPILAQKHCPGHSHQHVQKVMKPQ", "length": 366 }, "evidence": [ { "id": "G3MZM9", "url": "https://omabrowser.org/oma/group/G3MZM9/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "A2ADW8-1", "protein_name": "Predicted gene 15128", "gene_name": "Gm15128", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MANREDEIRQLRYLEAANSEEEYNEENDIQSESSRGQAFFPGHPRGRGHRRDSRGRNGHFFRQRFSANHPLLHLTRQVNLESLTRRNGNQSEERQLQQERIQLFFRSLHGLSQSHDHHIGRSHGHDSRRSRNRFRRAPVQSERSHVYSGRTNNYTDRPQHDLSNRPHNQLSVRPHPDLSGRPLHDYSGRPHQNHAVRLQHGHSDRYHLTHTERVLPNNSGIAHPGHTERDNQVQRGRAHDNQSGLAHHNHDGRSHHDHSGRAYHGHARRAHNNQSWRSDNNQSWRDLNQSWRGQNNQSQRGHDNQSQRGHDNQSRRGHDNQSQRGHDNQSQRGHNDQSWRAHNIRSRRDRYHTSLRSSSIQSWMLHERERYHGPRGRNGPRDASPPGSEPEIDRSSAIRERTDYLWVQEHRRNETVELNVGLEDGYSSAEESDESFDRLTCRSMLDTLY", "length": 449 }, "evidence": [ { "id": "G3MZM9", "url": "https://omabrowser.org/oma/group/G3MZM9/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "A2AGW6-1", "protein_name": "PRAME like 22", "gene_name": "Pramel22", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MHRLLREEALAISSLKDLPNMLFPVLFEEAFIFGYTKILKAMIPEWPFPYLSIAVLIDNCNLESLKAVLEGLDILLAQKVHSSRCKLKEISWRDTNHGLDGIRPGSHEVEGLSEFMEQKHPNCVEKKELKVTTELSVMNGRLNESDTYLLEWTQQRKDSIHLFCRKLVIQSLTKATVIEIFKIVNADCIPELELCSLCLEDLAFLNPYLRQMDNLLELTLDHITDSLSIGDSEMLEERMITLVSQLPTFPCLQKLCINDVYFIYGNLKEFLGCLKKPLVSFCISNCELSQSDLDYLPYCLNIFELKCLYIINIHLQYLCLEPLGFLLESVRHTLGCLALKSCNMGEPHFKSLLPALSQCFHLTDVNFQENELSLLSLKQLLQHTSKLTQLSYEMYPAPHECYDDRGVILSHRIEQFCPEVLDMLRAKRQPKDINFVTTQCSKCGIYYVYDLETQRCRFLK", "length": 460 }, "evidence": [ { "id": "G3MZM9", "url": "https://omabrowser.org/oma/group/G3MZM9/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "A2AGW7-1", "protein_name": "PRAME like 23", "gene_name": "Pramel23", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MNVNSPPTLMKLASQRLLREEALAISALKDLPNMLFPVMFEEAFINGHTKILKAMIPLWPFPYFSLGMMIKNLTLDTLKAVLQEIDILISKVVHSSRCKLKEIKWKNTDYGLQGIWPGSHEFDGLSEFMEQKQPDCGVKKELKVITHLKLMEGSLDECATYLLQWAQQRKDSIHLCCRKLKIQGSINATVIEIFKIVHADCIQELELCCLCLEDLDFLNPYLKQINNLIRLKLDEIKGTVSMGESRNIDEEKVITLISQLPTLQHLEKLCINDVSFIEGNLKECLRCLKKTLEILCITNCYLLQSDLDYLPYCLNILELKCLDFSNIPLSHLFLEHLRFLFERVRHTLECPILKSCEMGESQFNSLLPAISQCCQLTEVNFYDNELSLIFLKKFLHHTAKLSQLTYELYPAPLECYDNRDIILSHRLENFCPELLNILRAKKTAQGGHLCYNPML", "length": 455 }, "evidence": [ { "id": "G3MZM9", "url": "https://omabrowser.org/oma/group/G3MZM9/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "A2AHC7-1", "protein_name": "SSX member B14", "gene_name": "Ssxb14", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "METVISCEKIPMEVLHKPKNICKAFQDISTYFSGEEWGKLTEWQKSAYMYMKRNYTRMTGVTVNQPVFMSGKEQAKQSLVKGIEVHDSEDECFEESFGVTPRKRMKLTSVTISIHNVEGSLASGENDSNLAETDGIQVNVWSHRLRERKYRVIYSEISDPEEEEDDDY", "length": 168 }, "evidence": [ { "id": "G3MZM9", "url": "https://omabrowser.org/oma/group/G3MZM9/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "A2AK42-1", "protein_name": "Pre-mRNA-splicing factor CWC22 homolog", "gene_name": "Cwc22rt5", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MKSSVAHMKQSSGHNRRETHSSYCRSSSPEDRYTEQERFPRDRDYSDYSRSDYERSRRGYSYDDSMESRSRDREKRRERERDADHRKRPWKSPSPDRSPARGIRQSSPQEEPTWKKKKDELDPLLTRTGGAYIPPAKLRMMQEQITDKSSLAYQRMSWEALKKSINGLINKVNISNISIIIQELLQENIVRGRGLLSRSVLQAQSASPIFTHVYAALVAIINSKFPQIGELILKRLILNFRKGYRRNDKQLCLTASKFVAHLINQNVAHEVLCLEMLTLLLERPTDDSVEVAIGFLKECGLKLAQVSPRGINAIFERLRNILHESEIDKRVQYMIEVMFAVRKDGFKDHPVILEGLDLVEEDDQFTHMLPLEDDYNPEDVLNVFKMDPNFMENEEKYKAIKKEILDEGDSDSNTDQGAGSSEDEEEEEEEEEEEEEEGEDEEGGQKVTIHDKTEINLVSFRRTIYLAIQSSLDFEECAHKLLKMEFAESQTKELCNMILDCCAQQRTYENFFGLLAGRFCMLEKEYMESFESIFKEQYDTIHRLETNKLRNVAKVFAHLLYTDSLPWSVLECIKLSEETTTSSSRIFVKIFFQELCEYMGLPKLNARLKDETLQPFFEGLLPRDNPRNTRFAINFFTSIGLGGLTDELREHLKNTPKVIVAQKPEAEQKKTALTSSSSESSSASDSSDSDSDSSESSSESSSEASDSSSSSSTQSSTSAKGTRKKRQGKARGEEVDKLARGHQALERRQGGREDQRHQEGRTERARSERHRAQNSRDADWRDSLAKHIDDRSHENSHSRVGNGREQGSHREPEDRHGEPKKKQREKRFFL", "length": 830 }, "evidence": [ { "id": "G3MZM9", "url": "https://omabrowser.org/oma/group/G3MZM9/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "A2ANE0-1", "protein_name": "Reproductive homeobox 2F", "gene_name": "Rhox2f", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MERQSINYLLDVGPEEDEENANGVKTLMVLLAGDGRNEGESGRGLPGSGASAAEGYRAGEISAGGPAAQVADLMDDSNQEDLGATACDQEKEKQPEEPVPDSMGDLENVKRVSGPWSTVNPVRVLVPKFRHLWRHSFNVLQLQELESIFQCNHYISTKEANRLARSMGVSEATVQEWFLKRREKYRSYKRL", "length": 191 }, "evidence": [ { "id": "G3MZM9", "url": "https://omabrowser.org/oma/group/G3MZM9/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "A2ANE1-1", "protein_name": "Reproductive homeobox 3F", "gene_name": "Rhox3f", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MSMKPERSMSNWIHSNVEPAGRNLFQVNGHRSALLPELPQDYHRASRSVNGCETKMDNTQGTKVLPAEEARNEEDGGQVESALGATAARGRGKEALNGESPAAAGTAGLVEEDRNKEDGGTKGGEKNEQEVREQIPEHVEGESDQAEALRQVPRRRLHHRFTQWQLDELERIFRMNYFLSLEARKQLARWMGVNEAIVKRWFQKRREKYRWYKRL", "length": 215 }, "evidence": [ { "id": "G3MZM9", "url": "https://omabrowser.org/oma/group/G3MZM9/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "A2ASJ1-1", "protein_name": "PRAME like 14", "gene_name": "Pramel14", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MDLEAPPTLLQLAAQCTVRKEVLTISVLQNLPMKLFPPLFKEADILRKAKMIKLLVEYWPYPSLLVGLLIDKTNLETFQAILEGVGTWLKRKYRPRMGKLQVVDLRNGHHDFWDMLAGREGGDQLVETMPEKQEVEGHSRRQRLRVFSDLSFKSSRHEDKQQTHLLQWAKDREGFLHLCCEKLEIGALGVSKVKKVLKLLQPEFIKELELNTVGNLSKLTKLVPCISKMRNLQKLMLVRIFGRHTYTPLEERNVTKILSLFPKLSYLQHLTIDDVYFLRDHMNELFRYLEAPLLSLTITLCQISQSDLESFSQHWNYGQLKHLCLKGVSLSTLNVTPLKFFLESVADTLQTLELEDCRMKDSHLRILLPALTKCTRLTSINFYDNNISRDVLQDLLHRTANMSQLTMELYPAPVEVYNEWSYVQVERFSQLCAELMNTLITVRRPKSVCFGTYSCYDCDTHCIYGNQTTFCECLE", "length": 475 }, "evidence": [ { "id": "G3MZM9", "url": "https://omabrowser.org/oma/group/G3MZM9/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "A2ATW2-1", "protein_name": "Olfactory receptor", "gene_name": "Or4x15", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MADIHNVTEFFFLGLSSNQEVQRVCFVIFLFLYMAIVLGNLLMVVIVAVSRNLGSPMYFFLSSLSFVEICYSSTTAPKLIVDLLAEKKSISVWGCMAQLFFMHFFGGIEMFLLMMMAYDRYVAICKPLHYTSIMNRQVCTVLVGMAWMGGFVHSLAQVLLIFRLPFCGPNIIDHYFCDVLPVLKLVCSDTFLIGLLIVVNGGTLTVISFVVLLSSYAVILFHLRTQSAEGRRKALSTCGSHVTVVVIFFAPCVFIYLRPTATLPIDKMVTVFYTVITPLLNPIIYSLRNAEVKKVIKILCTRATKVDKK", "length": 309 }, "evidence": [ { "id": "G3MZM9", "url": "https://omabrowser.org/oma/group/G3MZM9/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "A2AWL9-1", "protein_name": "Reproductive homeobox 2C", "gene_name": "Rhox2c", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MERQSVNYKLDVGPEEDEENANGIKTLMVLLAGEGRNEGESGRGLPGSGASAAEGYRAGELSAGGLAAPVADLMDNSNQEDLGATGCDQEKEKQPEEPVPDSMGDLENVKRVSGPWSTVNPVRVLVPKFRHGWQQSFNVLQLQELESIFQCNHYISTKEANRLARSMGVSEATVQEWFLKRREKYRSYKRL", "length": 191 }, "evidence": [ { "id": "G3MZM9", "url": "https://omabrowser.org/oma/group/G3MZM9/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "A2AWM0-1", "protein_name": "Reproductive homeobox 3C", "gene_name": "Rhox3c", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MSMKPERSISNWIHSNVERAGRNLFQVNGHRSALLPELPQDYHRASRSVYGCETKMDSTQGTKVLPAEEARNEEDGGQVESALGATAARGRGKEALNGESPAAAGTAGLVEEDRNKEDGGTKGGEKNEQEVREQIPEHVEGESDQAEAPRQVPRRRLHHRFTQWQLDELERIFRMNYFLSLEARKQLARWMGVNEAIVKRWFQKRREQYRWYKRL", "length": 215 }, "evidence": [ { "id": "G3MZM9", "url": "https://omabrowser.org/oma/group/G3MZM9/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "A2BED8-1", "protein_name": "Predicted gene, 58953", "gene_name": "Samt1", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MDQLIVDTRSVIYRFINEKDCIYKLSGLLSSLAAFMLEVLIASILSWRLWEFDSNVVQFVSFGLFEAYYPQQFNISGTLTKMLVYTPIDSTWNISTEFMYAQNLVVWAILMKPVVLVFCVMAIKISCTKNPLVEMQIYCYKISALILSVSSMFTFVSVIWNHMVDFYGHTTLDFPSDFPVKKEALTSKHLTVVLPVGLLIATMSLFGVIMFLSEISDLKLKRPVKANDASKMGLLDA", "length": 237 }, "evidence": [ { "id": "G3MZM9", "url": "https://omabrowser.org/oma/group/G3MZM9/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "A2BEE3-1", "protein_name": "Spermatogenesis associated multipass transmembrane protein 1d", "gene_name": "Samt1d", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MDQLIVDTRSVIYRFINEKDCIYKLSGLLSSLAAFMLEVLIASILSWRLWEFDSNVVQLVSFGLFEAYYPQQFNISGTLTKMLVYTPIDSTWNISTEFMYAQNLVVWAILMKPVVLVFCVMAIKISCTKNPLVEMQIYCYKISALILSVSSMFTFVSVIWNHMVDFYGHTTLDFPSDFPVKKEALTSKHLTVVLPVGLLIATMSLFGVIMFLSEISDLKLKRPVKANDASKMGLLDA", "length": 237 }, "evidence": [ { "id": "G3MZM9", "url": "https://omabrowser.org/oma/group/G3MZM9/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "A2BEI6-1", "protein_name": "Myb/SANT DNA binding domain containing 5 family member 10", "gene_name": "Msantd5f7", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MQREDNRVQSVRSDKEANRRRRLRQEGQSSSGPCDSPWTEDEIWILLQEWAMVEYELGDPGNKMHAKAKSLSRRLSNRGLRKSKNSCLDVMVKMKDLHTRLCNERPRAYRLYSTYEWILYEILGHPRSQGGYVPGLWFDGHSKPPASYAPSLCIGGAISPGPSFSPWTDPEIKIFLQEWQVVEREIGHPGQKIKQKSSLVCQRLYHRGLFKDIQSCLDLMWTLKDLHSTLSRERSRTVPLFSPYRDYLERIFDPKCQRGHVPGALYNWSGYHRPSSSPQTPMVMPSPVYQPWDYGMSASSGQLHGNPSLIMSSQDSLVPRWDAWNATYPLPVQHVLLASLSGDNNFQLAWSPRDESSSPQ", "length": 360 }, "evidence": [ { "id": "G3MZM9", "url": "https://omabrowser.org/oma/group/G3MZM9/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "A2BEI8-1", "protein_name": "Myb/SANT DNA binding domain containing 5 family member 8", "gene_name": "Msantd5f8", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MQREDNRVQSVRSDKEANRRRRLRQEGQSSSGPCDSPWTEDEIWILLQEWAMVEYELGDPGNKMHAKAKSLSRRLSNRGLRKSKNSCLDVMVKMKDLHTRLCNERPRAYRLYSTYEWILYEILGHPRSQGGYVPGLWFDGHSKPPASYAPSLCIGGAISPGPSFSPWTDPEIKIFLQEWQVVEREIGHPGQKIKQKSSLVCQRLYHRGLFKDIQSCLDLMWTLKDLHSTLSRERSRTVPLFSPYRDYLERIFDPKCQRGHVPGALYNWSGYHRPSSSPQTPMVMPSPVYQPWDYGMSASSGQLHGNPSLIMSSQDSLVPRWDAWNATYPLPVQHVLLASLSGDNNFQLVWSPRDESSSPQ", "length": 360 }, "evidence": [ { "id": "G3MZM9", "url": "https://omabrowser.org/oma/group/G3MZM9/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "A2BFR3-1", "protein_name": "Histone H2A", "gene_name": "H2al1j", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MAKKMQRRRRQKRTHSQRGEFPLSLVDRFLPEGNHSGRLSSSAPVILDSVLEYLSSNILELAGEVAYTTGRKRIAPEDVGLVVQNNEQLCQLFKPGATSVFDPPEPDDN", "length": 109 }, "evidence": [ { "id": "G3MZM9", "url": "https://omabrowser.org/oma/group/G3MZM9/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "A2BFZ7-1", "protein_name": "BTB domain containing 35, family member 9", "gene_name": "Btbd35f11", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MGLLVSRVLRCRDSSLLEPQPEAIAGASYIPGSRKRKRNSLEELATSSNVHGPQNQGMYPHQVLNYIYWKRVKISSNDAYQNLFLDGHDSDIKIRALGKTWCLHKVFLCQSGYFANILKGTWRESHHGVINLIIKNEDIDTRSLHFVFGALYTDADLSITPLEVPQVLAAACLLRVDRVIQQCEGIMKETINRNTVCSYYLAAETYRLKAVKTRCFEWLLCNLMVHPSVALYKEVDLKLMYLLALSSDLLVMQKEIDVYTTLKIWMFLYLNPCWNGTMKQLLQHANNWLSTHMAYVDNISFLESEEGLIFQPVFKKLRFQHIICDLTSTTILEQDRLIPMAWLSPIYKQQWLTLLRTQEYGVIGPQVINEQELEECTMRCGTMIPKDGRYTWKWSVGRLGFPLRVTFTRQCVILRQRCQRCDGSACHNHIRNVIFRITLVCFDSNKRVTFRKTTGYKILTFEYKEEQIVMKLDSDVLTFPMCIFCNFLFVNLGNAENK", "length": 498 }, "evidence": [ { "id": "G3MZM9", "url": "https://omabrowser.org/oma/group/G3MZM9/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "A2BH64-1", "protein_name": "Secretoglobin, family 1B, member 30", "gene_name": "Scgb1b30", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MKLTGALLLLGAALLLTSEGDCGLCPVLQKKVHKFFDGTTEEYVEYLKQYNNDPLVLENAANIKKCSDRMLAEEDKTQATNFINKVTGSRSC", "length": 92 }, "evidence": [ { "id": "G3MZM9", "url": "https://omabrowser.org/oma/group/G3MZM9/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "A2BHG6-1", "protein_name": "BTB domain containing 35, family member 7", "gene_name": "Btbd35f7", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MGLLVSRVLSCRDSSLLEPQPEAIAGASYIPGSRKRKRNSLEELATSSNVHGPQNQGMYPHQVLNYIYWKRVKISSNDAYQNLFLDGHDSDIKIRALGRTWCLHKVFLCQSGYFANILKGTWRESHHGVINLIIKNEDIDTRSLHFVFGALYRDADLSITPLEVPQVLAAACLLRVDRVIQQCEGIMKETINRNTVCSYYLAAETYRLKAVKTRCFEWLLCNLMVHPSVALYKEVDLKLMYLLALSSDLLVMQKEIDVYTTLKIWMFLYLNPCWNGTMKQLLQHANNWLSTHMAYVDNISFLESEEGLIFQPVFKKLRFQHIICDLTSTTILEQDRLIPMAWLSPIYKQQWLTLLRTQEYGVIGPQVINEQELEECTMRCGTMIPKDGRYTWKWSFGRLGFPLRVTFTRQCVILRQRCQRCDGSACHNHIRNVIFRITLVCFDSNKRVTFRKTTGYKILTFEYKEEQIVMKLDSDVLTFPMCIFCNFLFVNLGNAENK", "length": 498 }, "evidence": [ { "id": "G3MZM9", "url": "https://omabrowser.org/oma/group/G3MZM9/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "A2BI40-1", "protein_name": "X-linked lymphocyte-regulated 4A", "gene_name": "Xlr4a", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MASKIKGRPPKQPKVTPALPSDDSQQLHENNPGNNLALETCGESSSSHGTGGPKPGPSKKTLNERKRKYGVSVNKTVQNIEWNVDHFLKVQHERRQELYKDYSHQFLTLVMMWNIDVDQIKKQAGKLSDILDEQQKLFQQFQSIHMQKIEEFKELCDRHLKNLQAIKCCRRKAIIEEARKLMDYLEKTVTEETVHVNKQEAKDGVQSSLLSLLIS", "length": 215 }, "evidence": [ { "id": "G3MZM9", "url": "https://omabrowser.org/oma/group/G3MZM9/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "A2BI45-1", "protein_name": "X-linked lymphocyte-regulated 5A", "gene_name": "Xlr5a", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MSNKEQKAMKKSGKHQRVHKTLPSDDFKNSDEVNPADKPAVGTSGMGSHSSGSDMQEAREPVQKKMQDFKGDDGTGLLMEKKKQFEEDVNASFRSLNENLQSILKAQQNSRQELKSLYCERFGSVYHNWLVEMDRTRDQEEYFSFITQQQMKILQTAIEDHETKLKNAKDMCDTFLKKANDLSKRQKTFIGGQHTIVEKEISKVQNRVIMETQDQDISMVETYLQSLIHESSEETI", "length": 236 }, "evidence": [ { "id": "G3MZM9", "url": "https://omabrowser.org/oma/group/G3MZM9/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "A2BI50-1", "protein_name": "X-linked lymphocyte-regulated 5B", "gene_name": "Xlr5b", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MSNKEQKAMKKSGKHQRVHKTLPSDDFKNSDEVNPADKPAVGTSGMGSHSSGSDMQEAREPVQKKMQDFKGDDGTGLLMEKRKQFEEDVNASFRSLNENLQSILKAQQNSRQELKSLYCERFGSVYHNWLVEMDRTRDQEEYFSFITQQQMKILQTAIEDHETKLKNAKDMCDTFLKKANDLSKRQKTFIGGQQTIVEKEISKVQNRVIMETQDQDIAMVETYLQSLIHESSEETI", "length": 236 }, "evidence": [ { "id": "G3MZM9", "url": "https://omabrowser.org/oma/group/G3MZM9/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "A2BI74-1", "protein_name": "SSX member B6", "gene_name": "Ssxb6", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "METVSSCEKIPMEVLYEPKNICKAFQDISTYFSDEEWVKLTQWQKSAYVYMKRNYIRMTDLGVTVNQPVFMRGKEQAKQSLVEGIEIHDSDDECFEGSFGVTPIKRMKLTSVTISIHNVEGSHDSGENDSNLAETGGIQVNVWSHRLRERKYRVIYSEISDPEEEEDDDY", "length": 170 }, "evidence": [ { "id": "G3MZM9", "url": "https://omabrowser.org/oma/group/G3MZM9/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "A2BIM8-1", "protein_name": "Major urinary protein 18", "gene_name": "Mup18", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MKMLLLLLCLGLTLVCVHAEEASSTGRNFNVEKINGEWHTIILASDKREKIEDNGNFRLFLEQIHVLENSLVLKFHTVRDEECSELSMVADKTEKAGEYSVTYDGFNTFTIPKTDYDNFLMAHLINEKDGETFQLMGLYGREPDLSSDIKERFAQLCEEHGILRENIIDLSNANRCLQARE", "length": 181 }, "evidence": [ { "id": "G3MZM9", "url": "https://omabrowser.org/oma/group/G3MZM9/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "A2CEK7-1", "protein_name": "Major urinary protein 14", "gene_name": "Mup14", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MKMLLLLCLGLTLVCVHAEEASSTGRNFNVEKINGEWHTIILASDKREKIEDNGNFRLFLEQIRVLENSLVLKFHTVRDEECSELSMVADKTEKAGEYSVTYDGFNTFTIPKTDYDNFLMAHLINEKDGETFQLMGLYGREPDLSSDIKERFAQLCEEHGILRENIIDLSNANRCLQARE", "length": 180 }, "evidence": [ { "id": "G3MZM9", "url": "https://omabrowser.org/oma/group/G3MZM9/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "A2CG71-1", "protein_name": "BTB domain containing 35, family member 19", "gene_name": "Btbd35f20", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MGLLVSRVLRCRDSSLLQPQPEAIAGASYIPGSRKRKRNSLEELATSSNVHGPQNQGMYPHQVLNYIYWKRVKISSNDAYQNLFLDGHDSDIKIRALGKTWCLHKVFLCQSVYFANILKGTWRESHHGVINLIIKNEDIDTRSLHFVFGALYTDADLSITPLEVPQVLAAACLLRVDRVIQQCEGIMKETINRNTVCSYYLAAETYRLKAVKMRCFEWLLCNLMVHPSVALYKEVDLKLMYLLALSSDLLVMQKEIDVYTTLKIWMFLYLNPCWNGTLKQLLQHANNWLSTHMAYVDNISFLESEEGLIFQPVFKKLRFQHIICDLTSTTILEQDRLIPMAWLSPIYKQQWLTLLRTQEYGVIGPQVINEQELEECTMRCGTMIPKDGRYTWKWSVGRLGFPLRVTFTRQCVILRQRCQRCDGSACHNHIRNVIFRITLVCFDSNKRVTFRKTTGYKILTFEYKEEQIVMKLDSDVLTFPMCIFCNFLFVNLGNAENK", "length": 498 }, "evidence": [ { "id": "G3MZM9", "url": "https://omabrowser.org/oma/group/G3MZM9/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "A2CG92-1", "protein_name": "BTB domain containing 35, family member 10", "gene_name": "Btbd35f10", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MGLLVSRVLRCRDSSLLEPQPEAIAGASYIPGSRKRKRNSLEELATSSNVHGPQNQGMYPHQVLNYIYWKRVKISSNDAYQNLFLDGHDSDIKIHALGKTWCLHKVFLCQSGYFANILKGTWRESHHGVINLIIKNEDIDTRSLHFVFGALYTDADLSITPLEVPQVLAAACLLRVDRVIQQCEGIMKETINRNTVCSYYLAAETYRLKAVKTRCFEWLLCNLMVHPSVALYKEVDLKLMYLLALSSDLLVMQKEIDVYTTLKIWMFLYLNPCWNGTMKQLLQHANNWLSTHMAYVDNISFLESEEGLIFQPVFKKLRFQHIICDLTSTTILEQDRLIPMAWLSPIYKQQWLTLLRTQEYGVIGPQVINEQELEECTMRCGTMIPKDGRYTWKWSVGRLGFPLRVTFTRQCVILRQRCQRCDGSACHNHIRNVIFRITLVCFDSNKRVTFRKTTGYKILTFEYKEEQIVMKLDSDVLTFPMCIFCNFLFVNLGNAENK", "length": 498 }, "evidence": [ { "id": "G3MZM9", "url": "https://omabrowser.org/oma/group/G3MZM9/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "A2CGC2-1", "protein_name": "BTB domain containing 35, family member 3", "gene_name": "Btbd35f4", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MGLLVSRVLRCRDSSLLEPQPEAIAGASYIPGSRKRKRNSLEELATSSNVHGPQNQRMYPHQVLNYIYWKRVKISSNDAYQNLFLDGHDSDIKIRALGKTWCLHKVFLCQSGYFANILKGTWRESHHGVINLIIKNIDTRSLHFVFGALYTDADLSITPLEVPQVLAAACLLRVDRVIQQCEGIMKETINRNTVCSYYLAAETYRLKAVKTRCFEWLLCNLMVHPSVALYKEVDLKLMYLLALSSDLLVMQKEIDVYTTLKIWMFLYLNPCWNGTMKQLLQHANNWLSTHMAYVDNISFLESEEGLIFQPVFKKLRFQHIICDLTSTTILEQDRLIPMAWLSPIYKQQWLTLLRTQEYGVIGPQVINEQELEECTMRCGTMIPKDGRYTWKWSVGRLGFPLRVTFTRQCVILRQRCQRCDGSACHNHIRNVIFRITLVCFDSNKRVTFRKTTGYKILTFEYKEEQIVMKLDSDVLTFPMCIFCNFLFVNLGNAENK", "length": 496 }, "evidence": [ { "id": "G3MZM9", "url": "https://omabrowser.org/oma/group/G3MZM9/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "A3KG49-1", "protein_name": "PWWP domain containing 4C", "gene_name": "Pwwp4c", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MDSSEYVLCGWKSQLCPARVLSRPRTPAHSKRRGVPFLEVQILPVGEKRRVRSSKVRPLAKSEIISINSLAGKESRGRGSPGQTRASRRALKVALDGLGEGSSFFQGGRAGSRRTSTLAPKVPKEQASSSSSSLGQRLRLRLRQLLPLSLCQRLHLHLRLRLHLHMHLCLQGRNQKGQGLSQRSPGKRVRPDPGPVMMGSQNVPAVPVGEAQAHTAAGLPRSEVEGDVLRGTRVWPSYSKKTPLGKAGGNPGKRKPGTGKRKLRSLSAPASRKGTRSKTEQQAASGPPRHISISPKALKQRVRCAGLEIRAAGAQRKTALAENKDHPGLGTPKPDSKRASAACMPPVLRLRRSLRIASRKKKTHVLCALCGLPEWEPQVHSKVTNTRFKRRGARVQKDAKATNVVSAQEPSTIEQGTLVWFKFQDLPFWPAVVKSVSKIDKMARVLLIEGNMQFERRGIRVPLRKLKHLDCGEKVSLVRRASRLYAQGINWCFSVIDHYREGLSRGSLLGSFMDYYTTQASYPLRRAVQEGDLHIDFPKVSYAELEDWEEETALGGKGPYKKLLPDRMRAAWDRANQKLVDFIVKRKGADQHLLDIVKGRKPSRWLDDLWKSKREVFCIETYLEDDDQLHLVARHLQEVAKEADEALLSLARGDKVRFTMEVLFPEAIIYSIAALDELSYKEAEEKYLRGPPVHYREKELFDKTILKAARKRSAARIRAARDPPVPTP", "length": 728 }, "evidence": [ { "id": "G3MZM9", "url": "https://omabrowser.org/oma/group/G3MZM9/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "A5WVZ0-1", "protein_name": "2.7.1.138", "gene_name": "cerk", "tax_id": 7955, "organism": "Danio rerio", "sequence": { "sequence": "MEKQSTLLCSELSVQRRLYEVTLNCAILAWKDVQNAKKHTGRAIYGAVKAGSHCVPVCEIIAVQEKEDDSPCKDTGKWQKVPQSPTDSCQHAFTVYYVERTRQHCWRCSNVTFQYSEHSLCLLWIQTIKEQLALLSAQSTEELAGVHQPLRRKTTRQADLRPQSGPHLFPGFHFHRRDWPHSFSAHPSELRFYIIADGKEPVMKCTGDCFSPRVQLHHLMQLIDGLHQASRKMQFNCQMNIMMFLPPLYHQPGNNGFSLFVSIVTEHANHARDHLKAEADLKKYDGVVCVGGDGMFSEIMHGLVSRTQQDAGVDENSTEETLIPCGLRIGIIPAGSTDCICYATVGSNDPVTSALHMVVGDSQPMDVCSVHSDDRFLRYSVSLLGYGFYGDVLKDSERKRWMGPARYNISGVKTFLSHRYYEGTVSFLPAEENLGTPRDKVQCRSGCSICRRSSSDKLLSKEDEASVSDVDCRDTWTVIRGKFLAINAANMSCACPRSPKGLSPSAHLADGTTDLILVRKCSRVDFLRHLLRHTNKKDQFDHSFVEVYRVKQFRFTPRFQECGSEMDLRESRAGGKHFFCQICRENRACGCMSSQSNWNCDGEILPHTAIQVRVHCQLIKLFARGIEEQPVFEDLYAHCQLNNPPNHEP", "length": 649 }, "evidence": [ { "id": "G3MZM9", "url": "https://omabrowser.org/oma/group/G3MZM9/", "database": "OMA" } ], "glygen_name": "Zebrafish", "common_name": "Zebrafish" }, { "uniprot_canonical_ac": "A5WWD5-1", "protein_name": "alpha-1,2-Mannosidase", "gene_name": "man1b1b", "tax_id": 7955, "organism": "Danio rerio", "sequence": { "sequence": "MLPSTRKDFVSLTLSESGSYSNSKQWRRQSCWRKWKQLSRLQRSLILLTLMLLLVCGIATSPTLIGHWRGMNGDDVKNSFVVDLKNEYRSILPEPPSERKDFDRRGAFGLEKLLQGKVNVSGVLGDQNHGLDLKNADKGSEGQKPIISWRGAVIEEEQASDTDTKDTENQGDPASLALAESRLEAVREAFRHAWKGYKDFAWGHDELKPISKSYGEWFGLGLTLIDALDTMWILGLQEEFAEAREWVAKELSFDKNVDVNLFESTIRILGGLLSTYHLTGDNLFLDKAKEIGFRLMPAFSTPSKIPYSDVNIGKGTAHPPRWTSDSTVAEVTSIQLEFRELSRLTGDPKYKLAVMEVMKQVHKLDGKQDGLVPMFINTNNGLFTHQGIYTLGARADSYYEYLLKQWIQGGRIEQELLEDYLQAVEGVKKNLLKKSTPLGLTFVGELSHGHFSPKMDHLVCFLPGTLALGVHYGLPADHMELAKQLIETCYQMYAQMETGLSPEIAHFNMHDGSTQDVDVKIADRHNLLRPETVESLFYLYRLTRDKKYQQWGWEILQNFNKYTRVPTGGYTSINNVRDPSYTSPRDKMESFFLGETLKYFYLLFSEDPTLISLDKYVFNTEAHPLPVWPQAE", "length": 632 }, "evidence": [ { "id": "G3MZM9", "url": "https://omabrowser.org/oma/group/G3MZM9/", "database": "OMA" } ], "glygen_name": "Zebrafish", "common_name": "Zebrafish" }, { "uniprot_canonical_ac": "A6NCW0-1", "protein_name": "Ubiquitin carboxyl-terminal hydrolase 17-like protein 3", "gene_name": "USP17L3", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MGDDSLYLGGEWQFNHFSKLTSSRPDAAFAEIQRTSLPEKSPLSSETRVDLCDDLAPVARQLAPREKLPLSSRRPAAVGAGLQNMGNTCYENASLQCLTYTLPLANYMLSREHSQTCQRPKCCMLCTMQAHITWALHSPGHVIQPSQALASGFHRGKQEDVHEFLMFTVDAMKKACLPGHKQVDHHSKDTTLIHQIFGGCWRSQIKCLHCHGISDTFDPYLDIALDIQAAQSVKQALEQLVKPEELNGENAYHCGLCLQRAPASNTLTLHTSAKVLILVLKRFSDVAGNKLAKNVQYPECLDMQPYMSQQNTGPLVYVLYAVLVHAGWSCHDGHYFSYVKAQEGQWYKMDDAEVTVCSITSVLSQQAYVLFYIQKSEWERHSESVSRGREPRALGAEDTDRRAKQGELKRDHPCLQAPELDEHLVERATQESTLDHWKFLQEQNKTKPEFNVGKVEGTLPPNALVIHQSKYKCGMKNHHPEQQSSLLNLSSTTRTDQESMNTGTLASLQGRTRRAKGKNKHSKRALLVCQ", "length": 530 }, "evidence": [ { "id": "G3MZM9", "url": "https://omabrowser.org/oma/group/G3MZM9/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "A6NCW7-1", "protein_name": "Inactive ubiquitin carboxyl-terminal hydrolase 17-like protein 4", "gene_name": "USP17L4", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MGDDSLYLGGEWQFNHFSKLTSSRPDAAFAEIQRTSLPEKSPLSSETRVDLCDDLAPVARQLAPREKLPLSSRRPAAVGAGLQNMGNTCYENASLQCLTYTLPLANYMLSREHSQTCQRPKCCMLCTMQAHITWALHSPGHVIQPSQALAAGFHRGKQEDVHEFLMFTVDAMKKACLPGHKQVDHHSKDTTLIHQIFGGCWRSQIKCLHCHGISDTFDPYLDIALDIQAAQSVKQALEQLVKPEELNGENAYHCGLCLQRAPASNTLTLHTSAKVLILVLKRFSDVAGNKLAKNVQYPECLDMQPYMSQQNTGPLVYVLYAVLVHAGWSCHDGYYFSYVKAQEGQWYKMDDAEVTVCSITSVLSQQAYVLFYIQKSEWERHSESVSRGREPRALGAEDTDRPATQGELKRDHPCLQVPELDEHLVERATEESTLDHWKFPQEQNKMKPEFNVRKVEGTLPPNVLVIHQSKYKCGMKNHHPEQQSSLLNLSSMNSTDQESMNTGTLASLQGRTRRSKGKNKHSKRSLLVCQ", "length": 530 }, "evidence": [ { "id": "G3MZM9", "url": "https://omabrowser.org/oma/group/G3MZM9/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "A6NDS4-1", "protein_name": "TBC1 domain family member 3B", "gene_name": "TBC1D3B", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MDVVEVAGSWWAQEREDIIMKYEKGHRAGLPEDKGPKPFRSYNNNVDHLGIVHETELPPLTAREAKQIRREISRKSKWVDMLGDWEKYKSSRKLIDRAYKGMPMNIRGPMWSVLLNIEEMKLKNPGRYQIMKEKGKRSSEHIQRIDRDISGTLRKHMFFRDRYGTKQRELLHILLAYEEYNPEVGYCRDLSHIAALFLLYLPEEDAFWALVQLLASERHSLQGFHSPNGGTVQGLQDQQEHVVATSQSKTMGHQDKKDLCGQCSPLGCLIRILIDGISLGLTLRLWDVYLVEGEQALMPITRIAFKVQQKRLTKTSRCGPWARFCNRFVDTWARDEDTVLKHLRASMKKLTRKQGDLPPPAKPEQGSSASRPVPASRGRKTLCKGDRQAPPGPPARFPRPIWSASPPRAPRSSTPCPGGAVREDTYPVGTQGVPSPALAQGGPQGSWRFLQWNSMPRLPTDLDVEGPWFRHYDFRQSCWVRAISQEDQLAPCWQAEHPAERVRSAFAAPSTDSDQGTPFRARDEQQCAPTSGPCLCGLHLESSQFPPGF", "length": 549 }, "evidence": [ { "id": "G3MZM9", "url": "https://omabrowser.org/oma/group/G3MZM9/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "A6NJZ7-1", "protein_name": "RIMS-binding protein 3C", "gene_name": "RIMBP3C", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MAKDSPSPLGASPKKPGCSSPAAAVLENQRRELEKLRAELEAERAGWRAERRRFAARERQLREEAERERRQLADRLRSKWEAQRSRELRQLQEEMQREREAEIRQLLRWKEAEQRQLQQLLHRERDGVVRQARELQRQLAEELVNRGHCSRPGASEVSAAQCRCRLQEVLAQLRWQTDGEQAARIRYLQAALEVERQLFLKYILAHFRGHPALSGSPDPQAVHSLEEPLPQTSSGSCHAPKPACQLGSLDSLSAEVGVRSRSLGLVSSACSSSPDGLLSTHASSLDCFAPACSRSLDSTRSLPKASKSEERPSSPDTSTPGSRRLSPPPSPLPPPPPPSAHRKLSNPRGGEGSESQPCEVLTPSPPGLGHHELIKLNWLLAKALWVLARRCYTLQEENKQLRRAGCPYQADEKVKRLKVKRAELTGLARRLADRARELQETNLRAVSAPIPGESCAGLELCQVFARQRARDLSEQASAPLAKDKQIEELRQECHLLQARVASGPCSDLHTGRGGPCTQWLNVRDLDRLQRESQREVLRLQRQLMLQQGNGGAWPEAGGQSATCEEVRRQMLALERELDQRRRECQELGTQAAPARRRGEEAETQLQAALLKNAWLAEENGRLQAKTDWVRKVEAENSEVRGHLGRACQERDASGLIAEQLLQQAARGQDRQQQLQRDPQKALCDLHPSWKEIQALQCRPGHPPEQPWETSQMPESQVKGSRRPKFHARPEDYAVSQPNRDIQEKREASLEESPVALGESASVPQVSETVPASQPLSKKTSSQSNSSSEGSMWATVPSSPTLDRDTASEVDDLEPDSVSLALEMGGSAAPAAPKLKIFMAQYNYNPFEGPNDHPEGELPLTAGDYIYIFGDMDEDGFYEGELDDGRRGLVPSNFVEQIPDSYIPGCLPAKSPDLGPSQLPAGQDEALEEDSLLSGKAQGMVDRGLCQMVRVGSKTEVATEILDTKTEACQLGLLQSMGKQGLSRPLLGTKGVLRMAPMQLHLQNVTATSANITWVYSSHRHPHVVYLDDREHALTPAGVSCYTFQGLCPGTHYRVRVEVRLPWDLLQVYWGTMSSTVTFDTLLAGPPYPPLDVLVERHASPGVLVVSWLPVTIDSAGSSNGVQVTGYAVYADGLKVCEVADATAGSTVLEFSQLQVPLTWQKVSVRTMSLCGESLDSVPAQIPEDFFMCHRWPETPPFSYTCGDPSTYRVTFPVCPQKLSLAPPSAKASPHNPGSCGEPQAKFLEAFFEEPPRRQSPVSNLGSEGECPSSGAGSQAQELAEAWEGCRKDLLFQKSPQNHRPPSVSDQPGEKENCYQHMGTSKSPAPGFIHLRTECGPRKEPCQEKAALERVLRQKQDAQGFTPPQLGASQQYASDFHNVLKEEQEALCLDLRGTERREERREPEPHSRQGQALGVKRGCQLHEPSSALCPAPSAKVIKMPRGGPQQLGTGANTPARVFVALSDYNPLVMSANLKAAEEELVFQKRQLLRVWGSQDTHDFYLSECNRQVGNIPGRLVAEMEVGTEQTDRRWRSPAQGHLPSVAHLEDFQGLIIPQGSSLVLQGNSKRLPLWTPKIMIAALDYDPGDGQMGGQGKGRLALRAGDVVMVYGPMDDQGFYYGELGGHRGLVPAHLLDHMSLHGH", "length": 1639 }, "evidence": [ { "id": "G3MZM9", "url": "https://omabrowser.org/oma/group/G3MZM9/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "A7TZG3-1", "protein_name": "Selection and upkeep of intraepithelial T-cells protein 9", "gene_name": "Skint9", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MESSASCLPGFFMSFLLLQNTVLTQAMRSDIKINIQVPDTEGLLLECTSGSLIPPAEMTWRDSNGNIIPHSTAFNSQDRDGLLYLKSSILLKNRAKGPITCSIYNVTTNQEKKRSIVLPDALFKSENMSLMSNKFSCPSIYLITIIFLNFLRGILVFCCLRRKPVCFRNLMSTVMEALYSKMGVCCLLIWECLLLVLYIAFLPIYVSFRSRAFLLDDTYPLYTNWLWNICIILTVIMVLFPGLILCLLWTLNCYGQVSSLPPTSMELSTKDSEQNSSKSDDSQENYDVNCKILETCESKIFSQHQESCEDDTASTLFIS", "length": 319 }, "evidence": [ { "id": "G3MZM9", "url": "https://omabrowser.org/oma/group/G3MZM9/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "A7XV14-1", "protein_name": "Selection and upkeep of intraepithelial T-cells protein 11", "gene_name": "Skint11", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MEPSASCLPGFFMVCILLKITVLTQVMSLDIQINTQIPDTEEGVLVECTAESLFPPAEMTWRDSKGNIIPPSSTFDSQDRAGLLCLKSTILLKNRTEGPITCSIYNKTTNQEKRRSIILSDVLFRPQYMSLMSNNLLYLGIYLIFILFLNFLKGILFCLTKRLVHFRKRMIKIKKVWSNKTRACCPLIWEFLEIVLFIAFLPLYLMFRIRVFTLDEAHILYNNWLWKVCKTLIAMMILFTVLILFLLWTLNRYGKMPCLSSMNIDVSTHDAEQNSSKSAKFQENYDVAGQMILETYEETIFCQHQESCEEYNYDPLLLSSLDALGTCEDEKFSQHQESFEEDEDLQSFSDFKIELYSKLGNLTH", "length": 364 }, "evidence": [ { "id": "G3MZM9", "url": "https://omabrowser.org/oma/group/G3MZM9/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "B0BMZ6-1", "protein_name": "Cilia- and flagella-associated protein 119", "gene_name": "Cfap119", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MITPRSSQSLEMKVQTELEHSPKLQEEPDRSPSLVDSSVIRIGTDEQNESPAEATSSPVEVAEDPGANLFPPPLPQPRICMWKYLDIHSMHRLEKAATVEEMREVLAELLELGGPEQSLRDAIILDLFSHALIFCRQQGFSLEQTSAACALLQDLHKACVATPLGNVEECYRYFTSVLFCHGVRRPPFSIDLFKEEQLLALADYVVNTYFRHFKLYKYVFTPQVRLDLSLSYMGLQSLHLWPEEKEDEEATVEQAATPQEEEPEAVTEAEQQPSEVCILQTYIKCQLNKELRQLQQLVEERLKESEERLSNRLAALERPYQTPPSKGKSKAK", "length": 332 }, "evidence": [ { "id": "G3MZM9", "url": "https://omabrowser.org/oma/group/G3MZM9/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "B0G0Z9-1", "protein_name": "Probable polyketide synthase 6", "gene_name": "pks6", "tax_id": 44689, "organism": "Dictyostelium discoideum", "sequence": { "sequence": "MNNLKNIDLIEKGVAIVGIGFRIPSGNNENSICSPDDLFNNLKNGFDGVSSTSERWSDNYHKLGEISSPNAGLLPLNEWKSFDPLFFGINPSEASLIDPQQRLLLKCTWEALEDASIDPISIRGTNTSVFIGASNIDYQHTNKHQDSVLKNAIAQSTCAISNRISYCFDFNGPSLSIDTACSSSLNAVSQGYHSILNGTSDISIVGGVNLILDVEMTKAYSYLSMLSKTHGKCKAFDESGDGFTRGECVGVVVLKNLQDAIKDGNRIYCVINGSSSNVDGNGNMDKVNFYSPSKQSQFNNINSAFKSTNDKLSINDIQYIEAHGTGTKTGDPIETEAISMAFKNRDKSAPILIGSIKSNIGHCEAGSGVASLIKCCLMFKYQCFLPNIHFKNPNPLIKFNEWNLKVVTSPIPFNKRNNEKPVSMMINNFGVTGSNCCLLISEFKNNNNFKENINLESQSVNDRVLIPFSANSSNSLNQYQSKFKNIINNQFNFIDFTAIQIYSKSNYLYQRSVVIASNSNELFENISNKKQIQTKNSIISNMSFKGKNPITIFVFSGQGSQYPKMALELYNNEVIFKKSIDLIDSKLSKYYGFSVWEKVKTIKDDDLTSIHDPIFAQPALCMISVSLFELYYHWGVNPSFILGHSLGEISASYCSGMIDLDTFCYTVYQRSIAQSKTNGCGRMLSINISDEEFKSMYSQKYPQIEIACYNSPQSIVVAGNESILNEISKELKEKEIFTAMLGSLSSFHTSSQQSTKDSILQLNIESNQPKVPIFSTVTTNLFNESNRFNSQYVYDNIIKPVKFTQTISNIYKHIESNQLDNDIVFIEIAPHPTLSFYIKQMVPSSLNESVSVYSALHKKKNDVEEFQQTISNLYCQNGYNINFKCQFNNKKSNLNIELPLYQWSDELYFAQNQVLEQHRKGGPPIDHLGLSNSYYSPFKNSYKTLIDINYKPFQYLKGHMVKGKYYFPGCGYIDNIIQLYKNQDIFISFIEFKTPLILIEGINQYLQTNIQQTGKSEYRAQFHFKDHKSNEWIQSSNSNFQLLDHGNDIPSNYNIKEIIKNKCNLSKLTKNELYKNIKSKTGLNYTGVFQGVTECYIGDNCTLSVVSLESQTNSFLNIPILDTCLHGMLILINDQCQIVFDKAIGFKYYSSNIPADFKENKDSFYVYSNLRPRVGGDSYHGTIIVMLSDGSVLYEIEEVVCKSLIPIKDSLKIEYPNDELYKVHLQSKDSPIPTPSSFKSIIYENDFFQSSLNIPEDLFKYISTLFYKDIIKRCPEININKINSHSVNEIISSFSKISKHERLFRFVFETIKENGILNSFEEKDDTYFEFNKVIIKSSRIISKLLFPLENDNDNEDLPQSLFQNGLMDKIYKCSYLRKKNQVISHVIKHSIKEIINNNIIIRILEFGGGTASLSVEVIEEIVTLLQENPNYQVEIEYTWSDISPAFIADAKNKINKIINDAAITNGLNVIYHPLTIGESLIETQSIKPSYYDFVIMSNVLHVVKDIKQAVEQMYQLLTTNGQLVFLEPPYKSVLNDSIVGSFEQWWSFTDTDIRKDRCGMPQQSWYQLLNSCNFKDIVMSKECIFFGSVIQAQKPPISLLNSQPKYDNIIIYGGSINSSFVENIKLDSNSKSLFQIETIQEFNKLISKSTITNDSIVYFIKTLETLSLDNFKQITLEYIEINQKLLQINSLCKHVLIVSDSRKTNYLASSAIGAARYFDEFPLLKLHTLDFDYDSTQNYINSKNNKMVQFINILTDSKTNVHKEMIIINNKVYYEIVQKEKNLKLKYNSESFENQNNLMCSLSPNLEYQLQSKQIKLRDNQVEVKTIATGINYKDYLNFSGSNSNGDDNTGLPQFGYEFSGIITRVGNNVKDYKVGDNVFGLSNSCTSSHIVTNFKKIQIKPSKISHIEASSIPIDYLTSFMSLFNVGSLNIEDNESILIHLGRDGFGLSTFEILKWKGFKSNLFVTVNSDKTKQYLLKKYGDLITGIYSNTDKSYVAEIKNKLIKLGSKKKGVDLILNTLPSDFMDSNFKLLTKYGRIIDLNSNHLNQSEFLKNINFKYNHGYHNFELSLFQKNKILKCLNEISNAIENGELKTIPIKEFTNLNIKDAIKYITNGNIEKITVSHDHEIYSDIIYRYLDEKEFSILKSNYQINSNNLGKNILITGQSGIILEILKWIIKYSNINTIENVIILSRSSLKWELELLINQTKLSNNNIKFHFKSVDVGDSEQVDNAINDILNENQQIRNIDSIFHFAFQQIACKVQEINMKHLNISHGAKSMGAINLHNQSIKRNWKLINFVMASSALSFIDSTDQCTYACANTLLDSFSKYRVSLGLPSTCINLGLIESTGFVSKNESISVFLDGNGIIPTPINRVLGLLDLQIQNASKFTNSMISNFKPSKFKNNQQISLFLKFDYLMNLKNNSEQTKKENTGNKNIDELFIEKVSELFSMDESKINKNLRLIDYGADSLIIVQLKNWIDKEIGINLITIQQLQNNTINISIKMILNSLMKNNQNKYLPSNRIDYWKNEMKFEESIKPIPNEIRSRNNNSGKIILLTGTTGFLGGFLLFNMLRLDSCKLIYCLIRNKSKSSYPLDEIINNLKYHQLYEKLNKSQISKIIPIIGDLSMNKLGLSNDDYETISKNVNLIINPGADINQKSSYQDCKLVNVNGVKEIIKLSLSSLKQRIPIVNFSSFSVFFNQSLDKNFDESVLPSIDNIDNLPTEYMKSKVVGEYILLEASKNYNIPSILIRPPSIFLNPETGIGHSSDLTLLMIQSCYELGYCPNQILNGFILINTITWLSNNITNIIMNDNCWTNSKMNIYNVHGKQIQSSLIIKPLEKHFNCKQINNNDWIDMVNNSNKKSCIKLKSFHSLENIFKSENKGYKSNESQSISLSTKSLLESMGSYNTDLKITDKMIISHIKHIFK", "length": 2924 }, "evidence": [ { "id": "G3MZM9", "url": "https://omabrowser.org/oma/group/G3MZM9/", "database": "OMA" } ], "glygen_name": "Cellular slime mold", "common_name": "Social amoeba" }, { "uniprot_canonical_ac": "B0G100-1", "protein_name": "Probable polyketide synthase 7", "gene_name": "pks7", "tax_id": 44689, "organism": "Dictyostelium discoideum", "sequence": { "sequence": "MNNFKNINLIEKGVAIVGIGFRIPSGNNENSISSPDDLFNNLKNGFDGVSSTSERWSDNFHKLGEISSPNAGLLPFNECKSFDPLFFGINPSEAPLIDPQQRLLLKCTWEALEDASIDPISIRGTNTSVFIGSSNIDYLHTNKHQDSVLKNVIAQSTCAISNRISYCFDFNGPSLSIDTACSSSLNAISQGYHSILNGTSDISIVGGVNLILDVETTKAYSYLSMLSKTHGKCKAFDESGDGFTRGECAGVVVLKNLQDAVKDGNRIYCVINGSSSNVDGNGNMDKVNFYSPSKQSQFNNINSAFKSTNEKLSVNEIQYIEAHGTGTKTGDPIETEAISMAFKNRDKSTPILIGSIKSNIGHCEAGSGVASLIKCCLMFKYQCFLPNIHFKNPNPLIKFNEWNLKVVTSPIPFNRKNEKPVSMMINNFGVTGSNCCLLISEFKKQDYEPYENNYKSNNKNILIPFSANSSNSLNQYQSKFKNIINNQFNFIDFTANQIYSKSNYLCQRSVIAASNSNELFEKILNKKQIQTKNSIISNMSFKGKNPITIFVFSGQGSQYPKMALELYNNEVIFKKSIDLINSKLSKYYGYSVLEKLRSIGDDDTTSIHDPNISQPAVCMISVSLFELYCHWGVNPSFILGHSLGEISASYCSGMIDLDTFCYTVYHRSIAQTKTHGNGRMLSINISDEEFKSMYSQKYPQIEIACYNSPQSIVVAGNESILNEISKELKEKEIFTAMLGSLSSFHTSSQQCTKDSVLKLNIQSNQPKVPIFSTVTTNLFNESNRFNSQYVYDNIINPVRFTQTISNIYKHIESNQLNNDIVFIEIAPHPTLSFYIKQMVPSSLNESVSVYSALHKKKNDVEEFQQTISNLYCQNGYNINFKCQFNNKKSNKKIDLPLYQWSDETYFAQTQTLEQHREEGPPIDHLGISNSFISPFNNSYKTLIDINNKPFQYLKGHMVKGKYYFPGCGYIDNIIQLYKNQDIFISFIEFKTPLILIEGINQCLQTNIQQTGKSEYRAQFHFKDQKSNQWTQSSNSNFQLLDHGNDIPSNYNIEEIIKNKCNLSKLTKNELYTHIKSKTGLNYTGVFKGVTECYIGDNCSLSVVSLESQTNSFLNIPILDTCLHGMLVLINDQCQIVFDKTIGFKYYSSNIPAYFKENKDCFYVYSHLKSKSADSYHGSIIVMLSDGSVLYEIQEVVCKSLIPIKDSLKIEYPNDELYKVHLQSKDSQIPTPSYFKSIIYENDSFHSIVNIPEDLFKYISTLFYKDIIKRCPEININKINSHSVNEIISSFSKISKHERLFRFVFETIKENGILNSLEENDDAYFEFNELVIKSSRIISKLLFPLENDNDNEDLPQSLFQNGLMDKFYKCNNFKKKNQIISHVIKHSIKEIINNNIIIRILEFGGGTASLSVEVIGEIVTLLQENPNYQVEIEYTWSDISPAFIADAKNKINKIINDAAITNGLNVIYLPLTIGESLIETQSIKPSYYDFVIMSNVLHVVKDIKQVVEQMYQLLTPNGQLVFVEPPYKSILIDSIVGSFDQWWSFTDTDIRKDRCGMSQQSWYQLLKTCNFKDIVMSKECIFGSVIQAQKPPISLLNSQPKHDNIIIYGGGNNSRFFENIKLYSNSKSLIQIETIQEFNQFINKSTITNDSIIYFIKTLETLSLDNFAQITLEYIEINKKLLQINSLCKHVLIVSDSRKTNYLASSVVGAARYFDEFQQLKLHTLDFDYDSTQNYINSKNNKMVQFINILTDSKTNVHKEMIIINNKVYYEIVQKEKNLKLKYNSESFENQNNLMCSLSPNLEYQLQSKQIKLRDNQVEVKTIATGINYKDYLNFSGSNSNGDDNTGLPQFGYEFSGIITRVGNNVKDYKVGDNVFGLSNSCTSSHIVTNFKNIQLKPSKISHIEASSIPIDYLASFISLFNVGSLNIEDNESILIHLGSDGFGLSTFEILKWKGFKSNLFVTVNSDETKQYLLDRYGDFISGIYSNTDKSYVTEIKNELIKLGSKKKGVDLILNTLPSDFMDSNFELLTKNARIIDLTSNHLNQSEFLKNINFKYNHSYHNFQLSLFQKNKIQKCLNEISNAIENGELKTIPIKEFTNLNIKDAIKYITNGNIEKITVSHDHEIYSDIIYRYLDEKEFSILKSNYQINSNNLGKNILITGQSGIILEILKWIIKYSNINTIENVIILSRSSLKWELELLINQTKLSNNNIKFHFKSIDVGDSEQVDNAINEILNENQQITNIDSIYHFAFQQITCKVQEINMKHLDISHGAKSMGAINLHNQSIKRNWKLINFVMASSAISLIGSTDLCTYACANTLLDSFSKYRVSLGLPSACINFGSIESTGFVSKNESVSVFLDGGGFHPTPINQVLGLLDLQIQNSGKFTNSMLSNFKPSKFKNNQQISLFLKFDYLMNLKNNSEQTKKENIGNKNIDELFIEKVSELFSTDESKINKNLRLIDYGADSLIIVQLKNWIDKEIGINLITIQQLQNNTINISIKMILNSLMKNNQCGREI", "length": 2513 }, "evidence": [ { "id": "G3MZM9", "url": "https://omabrowser.org/oma/group/G3MZM9/", "database": "OMA" } ], "glygen_name": "Cellular slime mold", "common_name": "Social amoeba" }, { "uniprot_canonical_ac": "B0G101-1", "protein_name": "Probable polyketide synthase 8/35", "gene_name": "pks8", "tax_id": 44689, "organism": "Dictyostelium discoideum", "sequence": { "sequence": "MNNLEIINLIDKGVAIVGVGFRIPSGNNENSICSPDDLFNNLKNGFDGVSSTSERWSDNFHKLGEISSPNAGLLPFNECKSFDPLFFGINPSDAHQIDPQQRLLLKCTWEALEDASIDPISIRGTNTSVFIGSSNIDYQHINKHQDSVLKNVIAQSAYAVSNRISYCFDFNGPSLSIDTACSSSLNAVSQGYHSILNGTSNMSIVGGVNLILDVGMIKAYSYLSMLSKTHGKCKAFDESGDGFTRGECATIVVLKNLQDAVKDGNRIYCVINGSSSNVDGGGHMDKVNLYSPSKQSQFNNINSAFKSTNGKLSINDIQYIEAHGTGTKTGDPIETEAISMAFKNRDKSTPILIGSIKSNIGHCEAGSGVASLIKCCLMFKYQCFLPNIHFKNPNPLIKFNEWNLKVVTSPIPFNKRINEKPVSMMINNFGVTGSNCCLLISEFKKQDYESYENNNNNKSNHKNILIPFSANSSNSLNQYQSKFKNIINNQFNFIDFTANQIYSKSNYLYQRSVVIASNSNELFEKILNKKQIQTKNSIISNMSFKGKNPITIFVFSGQGSQYPKMALELYNNDEIFKKSIDLIDSKLSKYYGYSVWGKLTTIKDDDLTSIHDPIFAQPALCMLSVSLFEIYCHWGVNPSFILGHSLGEISAAYCSGMIDLDTFCYTVYYRSIAQSKTNGCGRMLSINISDEEFKSMYSQKYPQIEIACYNSPQSIVVAGNESILNEISKELKEKEIFTAMLGSLSSFHTSSQQCTKDSILQLNIESNQPKVPIFSTVTTNLFNESNRFNSQYVYDNIIKPVKFTQTISNIYKHIESNQLNNDIVFIEIAPHPTISFYIKQMVPSSLNESVSVYSALHKKKNDVEEFQQTISNLYCQNGYSINFKCQLENKKSNQSINLPLYQWDDELYFAQTQTLEQYTKEGPPIDHLGLSNSYYSPFKNSYRTFIDINNKPFQYLKGHMVKGKYYFPGCGYIDIIIQLYKNQDIFISFIEFKTPLILIEGINQYLQTNIQQTGKSEYRAQFHFKDQKSNEWIQSSNANFQLLDHGNDIPSNYNIEEIIKNKCNLSKLTKNELYTQIKSKTGLNYTGVFQGATECYLGNDCSLSVLSLKSQTNSFLNIPILDTCLHGMLVLINDQSQIVFDKAIGFKYYSSNIPSDLKEYKDSIYVYSNLKPKNADSYHGSIIVMLSDGSVLYEIQEVIFKSLIPIKHSLKIEYPNDELYKVHLQSKDSQIPTPSSFKSIIYENDFFHSALNIPEDLFKYISTLFYKDIIKRCPEININKINSHSVNEIISSFSKISKNQRLFRFVFETIKENGILNSLEENDDAYFEFNELVIKSSKIISKLLFPLESDNDNEDLPQSLFQNGLMDKIYKCSYLRKKYQMISHVIIHSIKEIINNNIIIRILEFGGGTASLSVEVIGEIVALLQENPNYQVEIEYTWSDISPAFIADAKNKINKIINDAAITNGLNVIYRSLTIDESLLENQAIKPSYYDFVIMSNVLHVVKNIKQAVEQMYQLLTPNGQLLFIEPPYKSVLIDSIIGSFEQWWSFTDTDIRKDRCGMSQQSWYQLLKTCNFKDILMSKECIFVGSVIHAQKPPISLLNSQPKHDNIIIYGGGGNLSFVENIKLDSNSKSLIQIETIQEFNQLLSQSTITNDSIIYFIKTLETLSLDNYKQITLEYIEINQRLLQINSLCKHVLIVSDSRKTNYLASSVVGAARYFDEFQQLKLHTLDFDYDSTQNYINSKNNKMVQFINILVDSKTNVHKEMIIINNKVYYEIVQKEKNLKLKYNSESFENQNNLMCSLSPNLEYQLQSKQIKLRDNQVEVKTIATGINYKDYLNFSGSNNNNGDDNTGLPQFGYEFSGIITRVGNNVKDYKVGDNVFGLSNSCTSSHIVTNFKNIQLKPSNISHNEASSIPIDYLTSFMSLFNVGSLNIEDNESILIHLGSDSFGLSTFEILKWKGFKSNLFVTVDLDETKQYLLDRYGDFITGIYSNTDKSYVTEIKNELIKLGSKKKGVDLILNTLPSDFMDSNFELLTKSGRIIDLTSNHLNQSEFLKNINFKYNHGYHNFQLSLIQKNKIQKCLYEISHAIENGELKTIPIKEFTNLNIKDAIKYITNGNIEKITVSHDHEIYSDIIYRSLDEKEFSILKSNYQINSNNLGKNILITGQSGIILEILKWIIKYSNINTIENVIILSRSSLKWELELLINQTKLSNNNIKFHFKSVDVGDSEQVDNAINEILNENQQITNIDSIYHFAFQQITCKVQEINMKHLDISHGAKSMGAVNLHNQSIKRNWKLINFVMASSALSLIGSTDQCTYACANLLLDSFSKYRESLGLPSACINLGSIESTGFVSKNESISEFTDGIGYVPTPINLVLGLLDLQIQNAGKFTNSMLSNLISSKFKNIQQTSLFLKFDYLMNLNDNSEQTKKENIGNKNIDELFIEKVSELFSTDQSRINKNLRLIDYGADSLIIVQLKNWIDKEIGINLITIKQLQNNTINISIKMILNSLMKNNQI", "length": 2514 }, "evidence": [ { "id": "G3MZM9", "url": "https://omabrowser.org/oma/group/G3MZM9/", "database": "OMA" } ], "glygen_name": "Cellular slime mold", "common_name": "Social amoeba" }, { "uniprot_canonical_ac": "B0G110-1", "protein_name": "Acyl-coenzyme A oxidase", "gene_name": "", "tax_id": 44689, "organism": "Dictyostelium discoideum", "sequence": { "sequence": "MYKNRIEIIKKHLEVNNSQTTNNKDEVLEKELFNSIDTNINVGELKLLIDSVEESKYKDETREFIRNHPKFKENFIGLDMATYRQLVLEQCAAIANRGLIHFTDIKNNLHRYIGALEMFALYNNNILTKLSVQYTLFGGPIIFLGTSRHEKYIEDANTLKTMGCFAMTEIGHGSNVRGIETTAHYDKQTKEFIIHSPTPTSEKFWIGCAYLHATYAVVFANLIIDGTNYGIHAFIVPLRCPKSGAIMKGITIKDCGHKLGLNGIDNGQIRFDQVRIPRENLLNKYSDVSEDGVYKSQFNTPIKNFAATMSPFIVGRMAITKGCSGAAKTSLSIAIEFSHIRKQFGPSSNKELPLITLSSQQRRLMAPLARTILFDLYIQRLTNELCQEKLPASIHAHCSGIKAVYSWFCVAALQTCREACGGQGYRSANRIAEFKNDCDIICTYEGDNTVLMQQLAKYLLGVKQKQTNTTTNRIYLDGEDAKSLFFNFSNINQLFETREEMRLAELKQIIDNSKESAYFAFNNAIPWAVKLGFAHMTKIVFQNSINTLKLKNVKPLTHLIMLDALVSIEEDLGWFVSNHLISPNVAQSIPFLIQDLCFEVTKVSKQIIASFDIPENCKPSSKDLISDLF", "length": 629 }, "evidence": [ { "id": "G3MZM9", "url": "https://omabrowser.org/oma/group/G3MZM9/", "database": "OMA" } ], "glygen_name": "Cellular slime mold", "common_name": "Social amoeba" }, { "uniprot_canonical_ac": "B0G138-1", "protein_name": "Probable polyketide synthase 21", "gene_name": "pks21", "tax_id": 44689, "organism": "Dictyostelium discoideum", "sequence": { "sequence": "MKLENKEIAIVGIGFRIPQGKESINNGSVSHLWNNLKNGFSGIVETSERWSDNINLLGEVNNKFGGLLPLKEWSDFDPVHFAINPSEVPLMDPQTRLLLKCTWEALEDAFIDPIDIRGSNTSCFIGCSTLDYSTTNRDFNETSENYFASNVLHTISNRLSFSYDIRGPSMTIDTACSSSLNSIAMGFQSIQNGTSNLSIVGGVSLLLDPYISKSFSFLNMLSKKGKCKPFDSEADGYIRAESCGIVILKPLSDAIRDGNNIYCVINSFSSNVDGGGLNDKSNFYSPSKQSQSDNIKLALKSANMKASDISFVECHGTGTPTGDPIEVEGVSMALNSSKTSTPSKPLLIGSLKSNIGHSEAASGVASLIKCCLMFKNKHYAPNVNFDQPNPKINFKDWNIKVVTEAIPFTNNNEKPVSMVINNFGVTGSNCCLILSQFIEQSINQNGNGHSYPAESQQQQQQRFLIPFSANSVKSLKNYEDLIINDIKISTNSFKEFVKNQIYSKSKKLYQRSVLISSNWDQLKTKNKYFKTNNDKSSNITIKRNQPLVVIVFGGQGSQWNKMAQQLYECEPIFRSSMDKFNKELSKYYGYSVLDKLRSIKDDDIISIHQPIIAQPSILMLQISLFELYKHWGINVSFIVGHSLGEIATSYCSGMVDFQTVCKLIYHRSISQNNTNGCGKMLSVNISHSEFIELYSNKYPTIEVACYNSPTSIVIAGNENILKEISLNLKENNIFCAFLGSLSSFHTSSQHSTKNEILPLDIPSKQSRIPTFSTVTTNLFNHETTPFNSSYVYENIIQPVRFSQTISNLYQHIENNKLGNELIFIEVSPHPSLSFYLKQMIPKSSSYFNSVSVLTSTNKKNSNDLDEIHSTISQIYCLGYDVNFKCQFNHNDDDVSSIRNSKVNISLPNYQFDEQHYWKVDINFEQYRLNGPNVFNSLGKSMINYSSNNKSYESIIDINRNPFKYLKDHIVKGKYYFPGIGYADNIMKLYPNQDIIINNLEFLAPFVLKENVKHTLQTNVYQLGNTDYRVTFNIKDNKTNQWVQTCTGNFQLISLKDNNNDHSSKYDINQLLSECNFTTLSKQEVYKHSRSITGITHLGAFQGIEELYFGNDCIISKIQVNTENFDIDGKPVYQTYDKSFFNTALLDSCSQTIVGFITNSSQFVFERLEGLKVYSENIPTDKLKYKNIYCQAKFISLESDSYKSSVLVLLEDGTKLLEMDCISLHSTLPLLNSLLINNPTTELFTNNLQCKDSLVNILSIDNNQTFSSISSSNTVTEIIKQTIKPIINEKIVFRILQSFSDLELSKQIIETLNQIFDDNSLQEIDIEFTIIDNSNDKLPTLHDSSLIFKNDITQLKPSYYDIIINNNNDGDDETIIKSIFNILSSNGLLLIIGDDIGDKYNIDSLINLGFNENKIQKSNKVIQSQKSTILSNELTVVPNNKNDNIIIYCEKESKYTNEFMKLISNNHISCKQTIISNINEFNQLLPSITNDSIIYFIKSMEQLEMNNFKQITMEYIEINQQLLKHSLTCKHVLITIDSQIKNYLSSSIIGTARYFNEFPSLNLYSIDFDNQLSISSLLNKIINQLIENSNNHIQREYIIRNNSIYYEILKNEKNIKSNFNSNSFEDNDFMTLLDSTNLEYKLASKPKKLKKNQIEVKVLATGINYKDYLIYRGLVVIDENVSISKNPLGLEFSGIITRISNENQNCEFKVGDNVFGIACDTTASHVIADVLYVSHKPENISHVEAASLPVIFSTCLHGMFNIGNFNIDDDEVILIHSATGGIGLATLEILKWKGHKSPIFVTVGSKDKEQYLIDNYGSFITGIYSSRNKNYVNEIKSKLNQLYGTTGKFNGVDLIINTLPNEFTHSNFLCLKERGKIIDLSITHLNNNEFLNFNNFKFNKSYHNIELMHINKKVVSRLLKSISNALNENKLKPIPITTFQIEDVKEAIEYINQRKHIGKIVLDHSCSNGSIGSDGLLNQLIESDNNEKNHTILKYDFKIDTKNIIGKNIIITGQSGIILEILKWLIKYSPTESFENIIILSKSSLKWELELLINKTISRKDNNTKFHFKSVDVGDPIEMRKSINQILLENPNIDNIDSIFHYAFAQITKEVEEIDIESLDISHNAKTMGAINLHEISIEKSWKLKQFVMASSIASLFGSFNQCSYVSANLVLDSLSRYRKSIGLPSTCTNWGAIKSAGFVSRNELVSKMLDDQGFIPIPTNIILGSLDLQLQNSNKNSNLIVSKFNYDSIKKLSSETSTFQRLDFILNSIKEKDNDSNGGENSVSESIQTKILNKISELLSIEQSKINTDIRLSDYGADSLTSVQLKNFIDKDIKSNVITLQQLQNNTIDMNIQTILEQIKKLDSNETKGKSKNIIKKDSAPTLDYWRNEMKLDESIQAIKMNPIDFRNDSKVFLTGATGFLGVHLLSNLIKSPNCSVVYCLIRNKKSEPNPINAIINNLKHHKLYHFHNEFELSKIKVIVGNLASPLLGLSKLDFDYISNQINLIINSGADINLASNYEESKVVNIGGFIELIKLSTTGDYQKPIVGFSSVSVFFNASNCKEFDEETVIPTIENINNLPGGYMKSKVVVENLLREVAKRGIPSMLIRPPIIFSHEETGIGHDSDFFQLIIQSCYAVKKYPKIDKNILTSPIGWISLNTIKMIGNEKCWNKSSSNQLNIYSLNSEVSAMNPSFSFLEKQYGCEMVEYEQWKNIINQSKILSCVKLKTFHSLDDLYNIYNLGNGFGVSKKTKELLQSMNSYEGGMVNEKMIQNHINYIFKN", "length": 2779 }, "evidence": [ { "id": "G3MZM9", "url": "https://omabrowser.org/oma/group/G3MZM9/", "database": "OMA" } ], "glygen_name": "Cellular slime mold", "common_name": "Social amoeba" }, { "uniprot_canonical_ac": "B0G149-1", "protein_name": "Transmembrane protein 184F", "gene_name": "tmem184F", "tax_id": 44689, "organism": "Dictyostelium discoideum", "sequence": { "sequence": "MLSHINIIYIIWILLFFFTCLISFFLVNRHLVNYSSPNVQKNVVRIVMFLPLNSGLSILSSIFPGIAIFNSLVRNCYMAFTAHCFFSMMTNSIGEKNMLDLFESQGKMKFLCCKVMKLNRKLFNTLRFGSIQFFIVKIFCSIATITCISISEEVHSILNVQSFAPYEFLISLVASIFCTISLSIFLAISKEKLSQYWPMTKYRIMIFIFFIEQFEYLFFALIFLRGPFFLGFKNSFDQTIFILHFTVVVTMFLFSIVYLFIYSYKNYRNKASNEPLVGRNFKDSFGLLNYLDVLNPKDLFIDFASIFKTNNNKFKELVEENGDKKPKKNIEDQNQENSNDQPLSIQMA", "length": 348 }, "evidence": [ { "id": "G3MZM9", "url": "https://omabrowser.org/oma/group/G3MZM9/", "database": "OMA" } ], "glygen_name": "Cellular slime mold", "common_name": "Social amoeba" }, { "uniprot_canonical_ac": "B0G188-1", "protein_name": "GATA zinc finger domain-containing protein 16", "gene_name": "gtaP", "tax_id": 44689, "organism": "Dictyostelium discoideum", "sequence": { "sequence": "MNSYQIQNQPYQQIQNTHPSFQQVQPMQVPHLQQQQQHQTMIAQQQHTPPQQHTPPQMNMIQQHTQPMLSQPQISLQMQPPSPILASQQQQQHMQSSPILASSNLTNSNNASQTTLPIITSKLLLKKEPIDQEVVNSTHKTTTTNNKPPKQSKRKEKERLEEEKQTVAQQQQYQPPFIPLASNESNSDNPFKGSHAYGVSTTPYGNSQFNNNNNNNNNNNNNNNNSNNNSNNNNGNNNINNNNNNSNNNNNNNSNNNNNNSNNNNGNNNNNNNNNNNNNNNNHNTNNNNSNSNNNNNNGYQQDKKDDYSMMIWSEVGRKINILIRTTSKATKGTPISTQEIAEAIGASNGVTADLVELIKSINDPTYVRKLPPSSISNTPTMGSQSGGMVYNSSPMLSPSTMSPILQHGNYQMGGDMYFGGNNQFSGDKQSALNNVKNSKGGNTNNSGGGSSSGGTNDTQAKKPARRRKMRYGGTELSCHTCGVTNTPEWRRGPNGAKTLCNACGLAWAKSVKSEKQKELLANSTGVNITEPKKAQKRKKESSDNNNNNNNSSDSNKVLKSDDGSNNTNLTNDDDNGYPSSPNSSNSTSPSSHNINNNNNNNNNNNNNNNNNNNNNNNNNNNNIGNNNNNNINNNNTTNSITTPTTTPFPTTIPAMQIVSQLPVMVPQTQQQPHMSGNIISFQALHQNSGYQHYK", "length": 695 }, "evidence": [ { "id": "G3MZM9", "url": "https://omabrowser.org/oma/group/G3MZM9/", "database": "OMA" } ], "glygen_name": "Cellular slime mold", "common_name": "Social amoeba" }, { "uniprot_canonical_ac": "B0R191-1", "protein_name": "C-X-C motif chemokine 11-6", "gene_name": "cxcl11.6", "tax_id": 7955, "organism": "Danio rerio", "sequence": { "sequence": "MKTLAAFLLLSCLIAGEVNGQDRSSRARCFCVDKGLNMVLLKNLDKVEIFPPSPSCNKHEIVVTLKNGAGQKCLNPDSKFTKNVVLKAIGKRMQQSVPHSTTTGTVKSSMTSSTSAPTAFK", "length": 121 }, "evidence": [ { "id": "G3MZM9", "url": "https://omabrowser.org/oma/group/G3MZM9/", "database": "OMA" } ], "glygen_name": "Zebrafish", "common_name": "Zebrafish" }, { "uniprot_canonical_ac": "B1AV09-1", "protein_name": "Leucine zipper protein 4", "gene_name": "Luzp4", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MANHEDEIRQLRYLEAANSEEEYNEENDIQSESSRGQAFFPGHPRGRGHRRDSRGRNGHFFRQRFSANHPLLHLTRQVNLESLTRRNGNQSEERQLQQERIQLFFRSLHGLSQSHDHHIGRSHGHYSRRSRNRFRRAPVHSERSHVYSGRTNNYTDRPHHDLSDRPHNQLSVRPHPDLSGRPLHDYSGRPHQNHAVRLQHGHSDRYHLTHTERVLPNNSGIDHPGHTERDNQVQRGRAHDNQSGLAHHNHDGRSHHDHSGRAYHGHARRAHNNQSWRSDNNQSWRDLNQSWRGQNNQSQRGHDNQSQRGHDNQSRRGHDNQSQRGHDNQSQRGHNDQSWRAHNIRSRRDRYHTSLRSSSIQSWMLHERERYHGPRGRNGPRDASPPGSEPEIDRSSAIRERTDYLWVQEHRRNETVELNVGLEDGYSSAEESDESLDRLTCRSMLDTLY", "length": 449 }, "evidence": [ { "id": "G3MZM9", "url": "https://omabrowser.org/oma/group/G3MZM9/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "B1AY40-1", "protein_name": "SSX member B8", "gene_name": "Ssxb8", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "METVSFCEKVPMEVLYEPKNICKAFQDISTYFSDEEWGKLTQWQKSAYVYMKRNYIRMTDLGVTVNQPVFMSGKEQDKQSLVEGIEVHDSEDECFEGSFGVTPIKQMKLTPVTISIHNVEGSLASGENNSNLAETSGIQVNVWSHRLRERKYRVIYEEISDPEEEEDDDY", "length": 170 }, "evidence": [ { "id": "G3MZM9", "url": "https://omabrowser.org/oma/group/G3MZM9/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "B1AYI3-1", "protein_name": "Predicted gene 13272", "gene_name": "Gm13287", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MLPVHLFLVGGVMLSCSPASSLDSGKSGSLHLERSETARFLAELRSVPGHQCLRDRTDFPCPWKEGTNITPMTLGETTSCYSQTLRQVLHLFDTEASRAAWHERALDQLLSSLWRELQVLKRPREQGQSCPLPFALAIRTYFRGFFRYLKAKAHSACSWEIVRVQLQVDLPAFPLSARRGPR", "length": 182 }, "evidence": [ { "id": "G3MZM9", "url": "https://omabrowser.org/oma/group/G3MZM9/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "B1AZM5-1", "protein_name": "Predicted gene 12886", "gene_name": "Gm12886", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MVLPCSLWLLSVCLLSWCCDAKLPVALDPESESVPKPPVLKTATEIAAIVVFMKTSNETPKSGTYGQSLQDGKNKIKDVEKEVLDACSQLCQSLAQDPNLHHGYILRAYFKEHQFLCCF", "length": 119 }, "evidence": [ { "id": "G3MZM9", "url": "https://omabrowser.org/oma/group/G3MZM9/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "B1B0R2-1", "protein_name": "Spindlin family, member 2D", "gene_name": "Spin2d", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MESSKLTKKRAGRKRQRSRSPALPKRNIVGCRISHKWKEGDEHITQWNGTVLDQVPVNPSLYLVKYDGIDSVHALELYKDKRVLSLKVISKRVVSSGVTDSSFADAIVGKEVNHLFEGEHGSKEEWRGMVLSQAPILDNSFYITYERDPILYTYQLLDDFKEGDLQIMEGFSDPPSLDIDLELVDGLIGKHVEYTNDDGSKRDGLIIYQIETKPRVYLVKYEDDVHIHVTHLEKEL", "length": 236 }, "evidence": [ { "id": "G3MZM9", "url": "https://omabrowser.org/oma/group/G3MZM9/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "B4F7F0-1", "protein_name": "Claudin", "gene_name": "Cldn6", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MASTGLQILGIVLTLLGWVNALVSCALPMWKVTAFIGNSIVVAQMVWEGLWMSCVVQSTGQMQCKVYDSLLALPQDLQAARALCVITLLIVLLGLLLYLAGAKCTTCVEDKNSKSRLVLISGVIFVISGVLTLIPICWTAHAIIQDFYNPLVADAQKRELGASLYLGWAASGLLLIGGGLLCCACSSGGTQGPSHYVARYSSPVPHSRGPSEYPSKNYV", "length": 219 }, "evidence": [ { "id": "G3MZM9", "url": "https://omabrowser.org/oma/group/G3MZM9/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "B7ZW38-1", "protein_name": "Heterogeneous nuclear ribonucleoprotein C-like 3", "gene_name": "HNRNPCL3", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MASNVTNKMDPHSMNSRVFIGNLNTLVVKKSDVEAIFSKYGKIAGCSVHKGFAFVQYDKEKNARAAVAGEDGRMIASQVVDINLAAEPKVNRGNAGVKRSAAEMYGSSFDLDYNLQRDYYGGMYSFPARVPPPPPIALAVVPSKRQRISGNTSRRGKSGFNSKSGKRGSSKSGKLKGDDLQAIKQELTQIKQKVDSLLENLEKIEKEHCKQGVEVKNAKSEEEQTSSSSKKDKTHVKMESEGGADDSVEEGDLLCDDDNEDQGDNQLELIKDDEKGAEEGEDDRDRANGQDDS", "length": 293 }, "evidence": [ { "id": "G3MZM9", "url": "https://omabrowser.org/oma/group/G3MZM9/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "B8JKF6-1", "protein_name": "BTB domain containing 35, family member 13", "gene_name": "Btbd35f13", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MGLLVSRFLRCRDSSLLEPQPEAIAGASYIPGSRKRKRNSLEELATSSNVHGPQNQGMYPHQVLNYIYWKRVKISSNDAYQNLFLDGHDSDIKIRALGKTWCLHKVFLCQSGYFANILKGTWRESHHGAINLIIKNEDIDTRSLHFVFGALYTDADLSITPLEVPQVLAAACLLRVDRVIQQCEGIMKETINRNTVCSYYLAAETYRLKAVKTRCFEWLLCNLMVHPSVALYKEVDLKLMYVLALSSDLLVMQKEIDVYTTLKIWMFLYLNPCWNGTMKQLLQHANNWLSTHMAYVDNISFLESEEGLIFQPVFKKLRFQHIICDLTSTTILEQDRLIPMAWLSPIYKQQWLTLLRTQEYGVIGPQVINEQELEECTMRCGTMIPKDGRYTWKWSVGRLGFPLRVTFTRQCVILRQRCQRCDGSACHNHIRNVIFRITLVCFDSNKRVTFRKTTGYKILTFEYKEEQIVMKLDSDVLTFPMCIFCNFLFVNLGNAENK", "length": 498 }, "evidence": [ { "id": "G3MZM9", "url": "https://omabrowser.org/oma/group/G3MZM9/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "C0HKD1-1", "protein_name": "Spermatogenesis-associated protein 31F1B", "gene_name": "Spata31f1b", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MLSTMCFLWDTECPLYVYFCFFIIVLIVWQVRQNYQGLKCENRRSCCRRHQKVRQRAKDAASRARRLSREEDEKPCELLSIMKSQSWVPKQGNVRQLLCLDPSCQICEATTLEIRQLLQSKKSQISPALLGLPQRAACLEMPISSESFEWNQDFYSRYSTNSPVVPGNQTLTQLTEELTESTNADGVLLCWTDPLQIGQEFHLADMPMASETLVSPGLEEPVVLMNEEDTVHSNLNYIQQLQDHEALNSQIPFQTLTPQLTVTHPMAVSIVTDAPQPFLSPEVLRLLEIHVKKLMHFQRWGLPRRVEESLKQFMPNPPVYLPPEHNQPVSFILNTSSQDCVHRFEGISPETWYSYMDGQPIQTFWVSEWSSGDQGQRLSCKPIPSPVEKPLLTPDYELLHDLCLSPEGQVDGSQSNLQKKFTQLFCGLPSMHSESLGSTFLCTQGVSKNTLKPPYKEPHFLKVSPPIPLPEAAPPPSSTSPNESLDEPQRAQIGGVPFLTLSECKTLEWHLLQRQLQLQWGLPAVIARPPRVQSHTQYKHKPWNKAKPRETLKFFGPGKPFSALTRELFFIPQHARRLLEFHLQKRLIHLRWGLPQRIQRSINMLLSSTDLQSLPCGGSRLPNVSISQPGKPEAYGSGDTFLPTAGKGTTPMPHLFAKAQEMLKSHDTKCEQIREGKVPACVQSAWKGRIPGDLAAGTLFPNIPQGQPLELQAENNPDLHQEAVSWKPMDLDQEAQAFSGVFIEHCRRPQALSEETIKKLETTLRHKYLAFLSGLQALYCMAPTKATSPTVDQSVITTMPWSVKSPQKPLSQKSPLEALCLSGLEPCTQDDKETSANIAEEFQHGAQGHGRTEKVPPERQPLLNRPYSLDTEIMERVSFYLKRKALDIKLGISLKESVFQEPTATDLESESVQEPLGSPRESTLLQGPPTLCHVPVAPDPDKVCLKQPATAVQVVFQEQNQPSSRAVPHRSARQGSQVHRNMMEAQVHYVQMGTGGEMLNLGEPFSTESQSPGKSKSGYVPTVAGKRKIPGKPKVVGDLGEGDAGLGFSLVSLKTRQDGEQEKRLLHRQLQGSSLQAQTFHLEGACPHSPQESPELQFADPPPEVFMETDSEQDMEDSQSKESIVPEPARTAKAPQPMLSRASQGLPFPRSPTQRKPSQGQPGPGHVPPGHATPASPYTRPSRLPEAGLKNKMKLFFHSIKLKMKSKAHTEPSTVSTPGKVAKTSKENIDRGLPQAKSPTKKTKPEDFRGPKAQFSVVGPCLTPSYILDSKFWPRPRRVGSVSVLGHSYHCPRHCPRLAYANQQRNPP", "length": 1308 }, "evidence": [ { "id": "G3MZM9", "url": "https://omabrowser.org/oma/group/G3MZM9/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "C0HKD2-1", "protein_name": "Spermatogenesis-associated protein 31F1C", "gene_name": "Spata31f1c", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MLSTMCFLWDTECPLYVYFCFFIIVLIVWQVRQNYQGLKCENRRSCCRRHQKVRQRAKDAASRARRLSREEDEKPCELLSIMKSQSWVPKQGNVRQLLCLDPSCQICEATTLEIRQLLQSKKSQISPALLGLPQRAACLEMPISSESFEWNQDFYSRYSTNSPVVPGNQTLTQLTEELTESTNADGVLLCWTDPLQIGQEFHLADMPMASETLVSPGLEEPVVLMNEEDTVHSNLNYIQQLQDHEALNSQIPFQTLTPQLTVTHPMAVSIVTDAPQPFLSPEVLRLLEIHVKKLMHFQRWGLPRRVEESLKQFMPNPPVYLPPEHNQPVSFILNTSSQDCVHRFEGISPETWYSYMDGQPIQTFWVSEWSSGDQGQRLSCKPIPSPVEKPLLTPDYELLHDLCLSPEGQVDGSQSNLQKKFTQLFCGLPSMHSESLGSTFLCTQGVSKNTLKPPYKEPHFLKVSPPIPLPEAAPPPSSTSPNESLDEPQRAQIGGVPFLTLSECKTLEWHLLQRQLQLQWGLPAVIARPPRVQSHTQYKHKPWNKAKPRETLKFFGPGKPFSALTRELFFIPQHARRLLEFHLQKRLIHLRWGLPQRIQRSINMLLSSTDLQSLPCGGSRLPNVSISQPGKPEAYGSGDTFLPTAGKGTTPMPHLFAKAQEMLKSHDTKCEQIREGKVPACVQSAWKGRIPGDLAAGTLFPNIPQGQPLELQAENNPDLHQEAVSWKPMDLDQEAQAFSGVFIEHCRRPQALSEETIKKLETTLRHKYLAFLSGLQALYCMAPTKATSPTVDQSVITTMPWSVKSPQKPLSQKSPLEALCLSGLEPCTQDDKETSANIAEEFQHGAQGHGRTEKVPPERQPLLNRPYSLDTEIMERVSFYLKRKALDIKLGISLKESVFQEPTATDLESESVQEPLGSPRESTLLQGPPTLCHVPVAPDPDKVCLKQPATAVQVVFQEQNQPSSRAVPHRSARQGSQVHRNMMEAQVHYVQMGTGGEMLNLGEPFSTESQSPGKSKSGYVPTVAGKRKIPGKPKVVGDLGEGDAGLGFSLVSLKTRQDGEQEKRLLHRQLQGSSLQAQTFHLEGACPHSPQESPELQFADPPPEVFMETDSEQDMEDSQSKESIVPEPARTAKAPQPMLSRASQGLPFPRSPTQRKPSQGQPGPGHVPPGHATPASPYTRPSRLPEAGLKNKMKLFFHSIKLKMKSKAHTEPSTVSTPGKVAKTSKENIDRGLPQAKSPTKKTKPEDFRGPKAQFSVVGPCLTPSYILDSKFWPRPRRVGSVSVLGHSYHCPRHCPRLAYANQQRNPP", "length": 1308 }, "evidence": [ { "id": "G3MZM9", "url": "https://omabrowser.org/oma/group/G3MZM9/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "C0HKD3-1", "protein_name": "Spermatogenesis-associated protein 31F1D", "gene_name": "Spata31f1d", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MLSTMCFLWDTECPLYVYFCFFIIVLIVWQVRQNYQGLKCENRRSCCRRHQKVRQRAKDAASRARRLSREEDEKPCELLSIMKSQSWVPKQGNVRQLLCLDPSCQICEATTLEIRQLLQSKKSQISPALLGLPQRAACLEMPISSESFEWNQDFYSRYSTNSPVVPGNQTLTQLTEELTESTNADGVLLCWTDPLQIGQEFHLADMPMASETLVSPGLEEPVVLMNEEDTVHSNLNYIQQLQDHEALNSQIPFQTLTPQLTVTHPMAVSIVTDAPQPFLSPEVLRLLEIHVKKLMHFQRWGLPRRVEESLKQFMPNPPVYLPPEHNQPVSFILNTSSQDCVHRFEGISPETWYSYMDGQPIQTFWVSEWSSGDQGQRLSCKPIPSPVEKPLLTPDYELLHDLCLSPEGQVDGSQSNLQKKFTQLFCGLPSMHSESLGSTFLCTQGVSKNTLKPPYKEPHFLKVSPPIPLPEAAPPPSSTSPNESLDEPQRAQIGGVPFLTLSECKTLEWHLLQRQLQLQWGLPAVIARPPRVQSHTQYKHKPWNKAKPRETLKFFGPGKPFSALTRELFFIPQHARRLLEFHLQKRLIHLRWGLPQRIQRSINMLLSSTDLQSLPCGGSRLPNVSISQPGKPEAYGSGDTFLPTAGKGTTPMPHLFAKAQEMLKSHDTKCEQIREGKVPACVQSAWKGRIPGDLAAGTLFPNIPQGQPLELQAENNPDLHQEAVSWKPMDLDQEAQAFSGVFIEHCRRPQALSEETIKKLETTLRHKYLAFLSGLQALYCMAPTKATSPTVDQSVITTMPWSVKSPQKPLSQKSPLEALCLSGLEPCTQDDKETSANIAEEFQHGAQGHGRTEKVPPERQPLLNRPYSLDTEIMERVSFYLKRKALDIKLGISLKESVFQEPTATDLESESVQEPLGSPRESTLLQGPPTLCHVPVAPDPDKVCLKQPATAVQVVFQEQNQPSSRAVPHRSARQGSQVHRNMMEAQVHYVQMGTGGEMLNLGEPFSTESQSPGKSKSGYVPTVAGKRKIPGKPKVVGDLGEGDAGLGFSLVSLKTRQDGEQEKRLLHRQLQGSSLQAQTFHLEGACPHSPQESPELQFADPPPEVFMETDSEQDMEDSQSKESIVPEPARTAKAPQPMLSRASQGLPFPRSPTQRKPSQGQPGPGHVPPGHATPASPYTRPSRLPEAGLKNKMKLFFHSIKLKMKSKAHTEPSTVSTPGKVAKTSKENIDRGLPQAKSPTKKTKPEDFRGPKAQFSVVGPCLTPSYILDSKFWPRPRRVGSVSVLGHSYHCPRHCPRLAYANQQRNPP", "length": 1308 }, "evidence": [ { "id": "G3MZM9", "url": "https://omabrowser.org/oma/group/G3MZM9/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "C0HLM6-1", "protein_name": "Small integral membrane protein 20", "gene_name": "Smim20", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MAAARNLRTALIFGGFISMVGAAFYPIYFRPLLRLEEYQKEQAVNRAGIVQEDVQPPGLKVWSDPFGRK", "length": 69 }, "evidence": [ { "id": "G3MZM9", "url": "https://omabrowser.org/oma/group/G3MZM9/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "C7G009-1", "protein_name": "Thioredoxin fold domain-containing protein", "gene_name": "", "tax_id": 44689, "organism": "Dictyostelium discoideum", "sequence": { "sequence": "MNLILNGNWLVKFGAGWSGHCKKLQPVLENLAQHYNSDNENSKVKVAQVHCEEYESICIKYNIIGYPSLVFFDEGEIKHYRGPRLFENFKEAIDKHLNKEFVAFSQNQPSKIIVITNENLDLLLTGNWLVKFGAAWSLHCKKLQPVLENLAQHYNSDNENSKVKVAQVHCEEDNSICKKYNITGYPSLVFFNEGQIKHYTGPRQFENFKEAIDKHFKYGVKWSGHCKKFQPVLENLAQHYNSDIENSKIKVAQVHCEGDDSICKKYNITGYPSLVFFDEGETKPYRGLREFDKIKEATDKHFK", "length": 303 }, "evidence": [ { "id": "G3MZM9", "url": "https://omabrowser.org/oma/group/G3MZM9/", "database": "OMA" } ], "glygen_name": "Cellular slime mold", "common_name": "Social amoeba" }, { "uniprot_canonical_ac": "C7G010-1", "protein_name": "Calcineurin-like phosphoesterase domain-containing protein", "gene_name": "", "tax_id": 44689, "organism": "Dictyostelium discoideum", "sequence": { "sequence": "MKLKIKFSIISLFILKLVISKPILKFNNNNQFKIIQFTDLHYGSEPVDDIDTIFSQVNILDYEKPDLVILSGDMVTGYEEQFEDDDRNYWKYWNVFTRPFVERNIPWAITFGNHDGEGALSTNEILKIDQTFNLSLSQSNPVEMHGIANYVLKISSSNSLKSEPASLVYIFDSSTKGCSKLDWGCVHQDQVDWFKNTSKSFNKTDSIAFVHIPPVEIIDLWNNYPVYGNYSETSCCFDNDYGDFVSSLVESGDVHGLYFGHDHENDFHGDYKGVDLGYGRKSGAGSYSSKKPLGARVFQLTESPFTLSTWIREEDGNIVSQVIHPPSEFDRKPLQCKMKDKYSKKELIAIKVIGGFLIFLGIVVVGLIGFFGFKHYKKFKKQTLEMQNLV", "length": 390 }, "evidence": [ { "id": "G3MZM9", "url": "https://omabrowser.org/oma/group/G3MZM9/", "database": "OMA" } ], "glygen_name": "Cellular slime mold", "common_name": "Social amoeba" }, { "uniprot_canonical_ac": "C7G064-1", "protein_name": "SET domain-containing protein", "gene_name": "", "tax_id": 44689, "organism": "Dictyostelium discoideum", "sequence": { "sequence": "MKKDEKQFQQFPNKGRTVQANTDLPKGSTVFRCAPFASSIEDSDKLATEKYCGFCLQRIPKSDSKECLCKNCKLYSVCKSCRSINESAVEPFQIIIKSTFHLGSDTRDMRLLLRIIANIANGKQGMQTPIDDYQDFMGLTSTLDKVDKEHMTKFKRGVTSISSLISSVRGVGYLKNTITIHEILECFSSVLTNAHQFSYATSKEIGRGVCPTGYFNHSCMPNTTWSLDDQGMLLFSTSSNVKKGDELSLGYLANEYPLKNRRRELLDGYYFFCQCPLCEFQSNLSGYLCEKCKEPLLNDSIVYHEPSLTNPLDTGIGLIKHLRKMIDFRQQSVEFKKMFSSEQLSNILQKGVPKHIQSVFNCDASDNEELQQIVEISERSIKSLPLINGEPIDFYPLSDRNYYEYFKQLKNSKISSPEELQRIKDKILSLINPTIYNSFKDKIDKRLLI", "length": 449 }, "evidence": [ { "id": "G3MZM9", "url": "https://omabrowser.org/oma/group/G3MZM9/", "database": "OMA" } ], "glygen_name": "Cellular slime mold", "common_name": "Social amoeba" }, { "uniprot_canonical_ac": "C9JPN9-1", "protein_name": "Ubiquitin carboxyl-terminal hydrolase 17-like protein 12", "gene_name": "USP17L12", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MEEDSLYLGGEWQFNHFSKLTSSRPDAAFAEIQRTSLPEKSPLSCETRVDLCDDLAPVARQLAPREKLPLSNRRPAAVGAGLQNMGNTCYVNASLQCLTYTPPLANYMLSREHSQTCHRHKGCMLCTMQAHITRALHNPGHVIQPSQALAAGFHRGKQEDAHEFLMFTVDAMKKACLPGHKQVDHHSKDTTLIHQIFGGYWRSQIKCLHCHGISDTFDPYLDIALDIQAAQSVQQALEQLVKPEELNGENAYHCGVCLQRAPASKMLTLLTSAKVLILVLKRFSDVTGNKIAKNVQYPECLDMQPYMSQPNTGPLVYVLYAVLVHAGWSCHNGHYFSYVKAQEGQWYKMDDAEVTASSITSVLSQQAYVLFYIQKSEWERHSESVSRGREPRALGAEDTDRRATQGELKRDHPCLQAPELDEHLVERATQESTLDHWKFLQEQNKTKPEFNVRKVEGTLPPDVLVIHQSKYKCGMKNHHPEQQSSLLKLSSTTPTHQESMNTGTLASLRGRARRSKGKNKHSKRALLVCQ", "length": 530 }, "evidence": [ { "id": "G3MZM9", "url": "https://omabrowser.org/oma/group/G3MZM9/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "D3YTW8-1", "protein_name": "Vomeronasal type-1 receptor", "gene_name": "Vmn1r258", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MSVRGKSLKTTEEVALQIILLCQFGVGTMANVFLFVHNFSPVLTGSKQRPRQVILSHMAVANALTLFLTVFPNNMMAFAPRNPPTELKCKLKFFSHLVTRSTNLCSTCVLSIHQFVILVPISRGKLLLRASVPNLVSYSCYGCWFFSVLSNIHIPIKVTGPQITDNNTDSKSKFFCSTSGFTVRIVFLQFSHDATFMSIMVWTSVSMVLLLHRHRQQMQHILTPNQDARGQAESRATQTILIVVVTFVSFYLLNFICIIFHTFFIHYNLFIRLLGEILAAGFPTISPLLLIFRDPKNPCLELFHCFKPESLQNL", "length": 314 }, "evidence": [ { "id": "G3MZM9", "url": "https://omabrowser.org/oma/group/G3MZM9/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "D3YTX5-1", "protein_name": "Vomeronasal type-1 receptor", "gene_name": "Vmn1r259", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MSDHGKSVKTTEEVALQLLLLCQFGVGTLANVFLFVHNFSPVLTGSKQRPRQVILSHMAMANALTLFLTIFPNNMIAFAPKTPPTELKCKLEFFSHMVARSTNLCSTCVLSIHQFVTLVLVNRGKLILRASVPNFVSYSCYSCWFFSVLSNIHIPIKVTGPQITDNNTDSKSNLFCSTSGFIVGIVFLQFAYDATFMSIMVWTSVSMILLLHRHRQRMQHILTPNQNPRGQAETRATRTILMLVVTFVSFYLLNFICIIFHTLLMHSHLFIRLVSEVLAAVFPSICPLLLIFRDPKDPCSVLFNC", "length": 305 }, "evidence": [ { "id": "G3MZM9", "url": "https://omabrowser.org/oma/group/G3MZM9/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "D3YTY1-1", "protein_name": "Vomeronasal type-1 receptor", "gene_name": "Vmn1r107", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MSAHGKSVKTTEEVALQILLLCQFGVGTVANVFLFVHNFSPVLTGSKQRPRQVILSHMAVANALTLFLTIFPNNMSAFAPKTPPNELKCKLDFFSHMVARSKNLCSTCVLSIHQFVTLVPVNRGKGKLILRASVPNLWNYSCYSCWFYSVLSNIHIPIKVTGPQITDNNTDSKSNLFCSTSGFIVGMVFLQFSHDATFMSIMVWTSVSMVLLLHRHRQRMQHILTPNQDARGQAETRATHTILMLVVTFVSFYLLNCICIIFHAFSIHSRLFIRLVSEVLAAVFPSICPLLLIFRDPKDPCSVLFKC", "length": 307 }, "evidence": [ { "id": "G3MZM9", "url": "https://omabrowser.org/oma/group/G3MZM9/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "D3YTY2-1", "protein_name": "Vomeronasal type-1 receptor", "gene_name": "Vmn1r138", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MSVHDKSVKTTEEVALQLLLLCQFGVGTVANVFLFVHNFSPVLTGYKQRPRQVILSHMAVANALTLFLTIFPNNMMAFAPKTPPNELKCKLESFSRLVARSTNLCSTCVLSIHQFVTLFPLSRGKGKLILRASVQNLASYSCYSCWFFSVLSNIHIPIRVTGPQITDNNTDSKSNLFCSTSGFIVGIVLQFAHDATFMSIMIWTSVSMILLLHRHCQRMQDILTPNQNPRGQAETRATRTILMLVVTFVSFYLLNCICIIFHAFFIHSRLFIRLVSEVLAAVFPSICPLLLIFRDPKDPCSVLFKC", "length": 306 }, "evidence": [ { "id": "G3MZM9", "url": "https://omabrowser.org/oma/group/G3MZM9/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "D3YXI8-1", "protein_name": "Predicted gene 10377", "gene_name": "Gm10376", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MGSQAGSFRKASPQTPNIDENEKRIKRLEKLKRDLQNIKNERDILQGILAKYKDLNDRTNFETFMLEMQNNQMMTDLKRMSQDISEALYKCQHLTKENQLYCCRNCHLLIESNLIQHKVRMLWKENRQLLRKQIALEECNIKTKILCKEGSQKIKDEYSRQAAGKQIIVVPGSKEEAVMSNPCA", "length": 184 }, "evidence": [ { "id": "G3MZM9", "url": "https://omabrowser.org/oma/group/G3MZM9/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "D3YYI9-1", "protein_name": "Predicted gene 7347", "gene_name": "Gm7347", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MALFARLCRLFQRVNVDGRETREGRKDADLPSERNEGRRRWTWRMCMAHRQTTSPVPVKSKKQFEKEEKELIKKIQLTTKETNELRDRLIYVTEGSMNKRPYHRQTRHYKELKLKEKEIMTFLHDLEMKNMEARENNQELKKEKNFYRNLHTRILLGENLIKKKLAILQQESKEIHADWAIIQQRLVELNLSGKDEQEKTSNLEAQENQVSEAARELGLATAEEDSILQNELPCQEAPAEHHPQHPSSSSDESSSDESSYSTCPEWE", "length": 267 }, "evidence": [ { "id": "G3MZM9", "url": "https://omabrowser.org/oma/group/G3MZM9/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "D3YYY1-1", "protein_name": "Secretoglobin, family 2B, member 7", "gene_name": "Scgb2b7", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MKGTLLLLGLLVTGELSFQTTEACFPFFEAYASVLSGSRVWLYQELQAFDATAEEKVALEKIQDCYSEESIRNILLEPKIMEAMVASPECLSYYGLDNIRSILDYISKLLGE", "length": 112 }, "evidence": [ { "id": "G3MZM9", "url": "https://omabrowser.org/oma/group/G3MZM9/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "D3Z236-1", "protein_name": "Predicted gene 3676", "gene_name": "Gm3676", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MGSQTVSFRKASPQTPNIDENEKRIKRLEKLKRDLQNIKNERDILQGILAKYKDLNDRTNFETFMLEMQHNQMMTDLKRMSQDISEALYKCQHLTKENQLYCCRNCHLLIESNLIQHKVRMLWKENRQLLRKQIALEECNIKTKTLCKEGSQKIKDEYSRQAAGKQIIVVPGSKEEAAMSNPCA", "length": 184 }, "evidence": [ { "id": "G3MZM9", "url": "https://omabrowser.org/oma/group/G3MZM9/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "D3Z8D1-1", "protein_name": "SIGLEC family like 1", "gene_name": "Siglecl1", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MLWGLRSLLLLHLGFLSPVLVDTKKTAVEDGLCSTVPCVIEFSKAPLRKPMIVSYRLNENISFHAGTSQPRGPVADLSTEEVEYCILLTHNMLGRKNMTYSLYVGLGAQKDLTQKQELHIPGSSMAGEPVSLTCTIHSTCQESKALFLSWKGPIMSSSTTVPINPSSALAIDPKPEDQDTTLRCHLKLSLDNLSSSKVVKLQLVSPARLLNYSCLLKRTLTCSCSFHGIPTPSVQWWVGRTPVSVNSIDAILHMTSTTLESWTNSTIHLMWEPEIIKSLRCEGKNQYGVHASGIFLIPDKSSVSSVFLRGLIQGIVYGAIASALFFFFLVVLGMKILNWWEENQTCKNEEAPTLKKPVWGGAKPAEVGS", "length": 369 }, "evidence": [ { "id": "G3MZM9", "url": "https://omabrowser.org/oma/group/G3MZM9/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "D3Z8T0-1", "protein_name": "High mobility group nucleosomal binding domain 2, pseudo 3", "gene_name": "AABR07053402.1", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MPKRKAERDAQGDEAKAKDEPQRRSARLSAKPAPSKPKKAPAKKREKIPKRKERKADAGKDANNPAENRDAKTGQAQKAEGAGVAK", "length": 86 }, "evidence": [ { "id": "G3MZM9", "url": "https://omabrowser.org/oma/group/G3MZM9/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "D3Z9U8-1", "protein_name": "S100 calcium binding protein A7 like 2", "gene_name": "S100a7l2", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MAQNLTSSEQEVMKLFDLFQNYHVRRTDKLDVQETKRVLREFFPNFMKALNASGIKILNDLEKEITLDEIWDMIGRMAMAYNKKNSNALKD", "length": 91 }, "evidence": [ { "id": "G3MZM9", "url": "https://omabrowser.org/oma/group/G3MZM9/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "D3ZAM9-1", "protein_name": "Olfactory receptor", "gene_name": "Or4f60b", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MKKVNYSVTSEFVFLGFTNSWDIQLLLFLVSSMFYVACIMGNCLIIFTVASDTHLHSPMYFLLANLSFIDVGISSATSPKMISDLLKKHKVISFRGCVIQIFFNQAIGGAEMVLLIAMAFDRYVAICKPLHYLTMMSPQMCLFFLITAWVVGLMHSVIQLIFIVNLPLCGPNILDSFFCDLPQFIKLACMNTYRLELLVSISSGFMSLVSFFLLSISYIVIILTVLKHSSSGAYKALSTLSAHVTVVVLFFGPAIFFYIWPSSTHLDKFLVLFDAVVTPFLNPVIYTLRNKEMKRAMRRVFRHLMGYRQIS", "length": 311 }, "evidence": [ { "id": "G3MZM9", "url": "https://omabrowser.org/oma/group/G3MZM9/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "D3ZC26-1", "protein_name": "Ferritin", "gene_name": "Fthl17fl", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MAEASSQVRQNYDRCCEDAINNHIRLLLQASYSYLSMAFYFDRDDVALGNFKRFFLSKSHNCKASAEMFVFMQNKRGGHVFLPSIAKPDRESWHGGLRAMECAFRMEMTINQSLLNMHELAKGKDDAHLCDFLGQHCLDQQVHVLKKMGGYLTNLRQMGAPEQGLAEYLFDKLSLS", "length": 176 }, "evidence": [ { "id": "G3MZM9", "url": "https://omabrowser.org/oma/group/G3MZM9/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "D3ZCM9-1", "protein_name": "Dynein axonemal assembly factor 3", "gene_name": "Dnaaf3", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MTTPAGSGNGFGTVSWWGLSPALDLQAESPPVDPDSQSKTEHKIPELDALLLGSVDGRHMLRTLARAMLWPLRRFNFYVLENNLEAVARHMLIFSLALEEPEKMGLQERSETFLELWGNALLRPSVAAFLRAQASHLSNLVPEPDRLEELLPWLSLRPLKFRERDALEAVFRFWSGGEKGPEVFPMSRLWDSRLRHYLGSRYDARRGVADWDLRMKLHDRGAQVIHFHEFRRWRDTGVAFELRDLSAYHVPNRTMASGRLLSHRGERVAARGYWGDIATGPFVAFGIEADDKSLLRTSNGQPVKTASEITQHNVTELFRDVAAWRGPRAIKGNVEETKSPEPDAPAQEPFTIHFLPLDSSQTLHHKTCYRGRFQLLYVSCGMIHLLSPELGACVAPGGNLVVELARYLVDLRPKELKAFSDRVVEIAQAAGFAPHTGTKPSETFARFYKLGDSTRGGGDSAVESGPVPSKVLAPTPESINPPQADQAPSLEVMSPPKVDQTPPLEAMSPPEADQAPPLEAMSPPRADQIPPLEAMSPLQAEVVLPLEAISPPQADLAPPPEVISPVQEALAMSSAIAPLKHVT", "length": 583 }, "evidence": [ { "id": "G3MZM9", "url": "https://omabrowser.org/oma/group/G3MZM9/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "D3ZCW3-1", "protein_name": "SPATA31 subfamily E, member 1", "gene_name": "Spata31e1", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "METFLLLMNSISDFWMSSSSMSTVMDMIFAILCGVGFFFLLIPFLKEYPGSPPPGSKKNISEVVKRRQSKDRKKSVTVDGCRDSQKNSLDIQHDLQTMESPIQHLLLDSSPHPFWNSKEKLNQLSLPQLFSYLKVLEALIQQKFNQLLLGLSSVLSESVVATAWVSREPSSGERKTVRFSDSLGFDQALPLAKGPPQRCLDQPLPHQLVTPSLVGMTEIQEQENLPNSISYQTPSIFQSRARGTAYPTTATGIQVPLPTTNEPCHPGLNWKDIPSCKVQNCQGASSQPTESLARCTLPTKNTRSASIPPEHYLMVHHHEQPQHEEKAINLGEQQRTHARFLPSKEPAQLQGDSPPNSNGYGKNWPELNQPAQPSTLNSKTYKWNQMMGPVPTGMLLKKVIAKYGIPNTIKKDLKLRVKDLLCTSSSTPGESLETKNLTLRTDEHSMNTTENLSFLDPKTTMMKSNIMQLPMKHRQLPCDSKAEPYTKAAFILENLHHQDPGGIRVETASSARLRSPLFEQSPPEVQKTQSSPPPIDSHGHSRSHPDQWQRYQSVQPHALCSQAQPQQSRSIQGTGRSILQPNISVWMSKHERWMRSEDVASGHTSWSSRTVGYRDRVSPSVAKQTNILKIKEESPHVWRANLGSGEITNEQALNNSNEDFEPIEAKRSQGHLQMPTQQNTGYLHLKTEEYSNNDLKVNKQPQAWSVSHHADGSNTVHHAMVKLPSQHSLPSLQNGWQDPKTSQGLGDLLMNRDQSVETQFRVHKDKTEATNDSVFHPSEKRPSNLKYGGISQGERLGRVKSSISSFTQLKDSAKTESKSSPNIGGKREAPSKSSLKFIWNGAQYENLSTKLKGQRDSLKKDIPPPVTEQTQEVVHRINVIYSTAVELQSLMDSLVHKLVKTVGEPSELTRKHMTKVQEYKMESLPFQLGSSSQPSKGLHDPNKSRSVRRMSDDHTSPKEPNNHTFTYRGNRDKMQAGVDVQRVCYQHLDKVKIGFGQHSTPMRNGNPCFHKKAGDKQESSLADQSTGDADQTKPKNEIVGSPHRIPERHNQSSRYREIRDNQEPSVDHKAIDPHQNTKKGMGYSQLMSPKENHPVKISGTAAQGASDPEEIRTKSGKECSPHRSPKMHDHSLRHREVRDKPQPGINTQRAYDQHLNSPKKRMTSENLLTPKGTNHPCWHRVTGDKQQSSLSDQRACDPEQMRRSGMSSYPQRSPKVYHLSCSSEKIGEKLLPLVNDQRTHDKHPNSVKTRGCDNLPTPKGSNHPQGYRVIEDKQQLGLAYRRTCDPGQIKKSGMGKGPCKDTEECNLLYRYKIIGNKQQPGIVHRACDRHQSSKEGMGQGQPMNPKVCHSAKHRRTGGQDQSGVAAQGASNPR", "length": 1373 }, "evidence": [ { "id": "G3MZM9", "url": "https://omabrowser.org/oma/group/G3MZM9/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "D3ZDD6-1", "protein_name": "Synaptonemal complex central element protein 3", "gene_name": "Syce3", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MADSDPGERSYDNMLKMLSDLNKDLERLLEEMEKISVQATWMAYDMVVMRTNPTLAESMRRLEDAFLNCKEEMEKNWQELLTETKRKQ", "length": 88 }, "evidence": [ { "id": "G3MZM9", "url": "https://omabrowser.org/oma/group/G3MZM9/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "D3ZDJ1-1", "protein_name": "Olfactory receptor", "gene_name": "Or13c3f", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MDDMDKNNQTFVSEFLLLGLSGYPKTEILYFVIVLVMYLVILTGNGVLIIASIFDSHLHTPMYFFLGNLSFLDICYTTSSVPSTLVSLISKKRNISFSGCTVQMFVGFAMGSTECLLLGMMAFDRYVAICNPLRYSVIMSKEVYVSMASASWFSGGINSVVQTSLAMRLPFCGNNVINHFTCEVLAVLKLACADISLNIVTMVISNMAFLVLPLLLIFFSYVFILYTILRMNSASGRRKAFSTCSAHLTVVVIFYGTIFSMYAKPKSQDLTGKDKFQTSDKIISLFYGVVTPMLNPIIYSLRNKDVKAAVKYILKQKYIP", "length": 320 }, "evidence": [ { "id": "G3MZM9", "url": "https://omabrowser.org/oma/group/G3MZM9/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "D3ZDT4-1", "protein_name": "Transmembrane protein 92-like", "gene_name": "LOC100364194", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MQEAWVLDALTVIFGLLFSLQGVSSNKTIYKCEDIHCPKGFRCCDNECCLERKIWNTDNEPFRILFIILLVMLPLLCICGLVRRFCPKCRELQHEVRTADHQSPPDPPSIAPLESIWVTSLDPPPPYSQVVQKSTPTEPPPPYSLRPEDSTCPMRETSHETL", "length": 162 }, "evidence": [ { "id": "G3MZM9", "url": "https://omabrowser.org/oma/group/G3MZM9/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "D3ZFJ9-1", "protein_name": "Family with sequence similarity 24 member B", "gene_name": "Fam24b", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MFSSFDLRTIIMIVIGSGILAAMFLLTGVVLCLYSKIARALNPSGTGKELDDQLCSDPCKTTQDQIIRVNSLNADTCRPFHGSTIGLENCQPLQCFSACGTYEGANSLTPCLCNTKEGL", "length": 119 }, "evidence": [ { "id": "G3MZM9", "url": "https://omabrowser.org/oma/group/G3MZM9/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "D3ZFW5-1", "protein_name": "Transmembrane protein 107", "gene_name": "Tmem107", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MGRISGLVPSRFLTLLAHLVIVITLFWSRESNIQACLPLKFTPEEYEKQDNQLVAALCLTLGLFAVELAGFLSGVSMFNSTQSLLSIAAHCSASVALSFFIFERWECTTYWYIFAFCSAFPAVTETALFIAVFGLKKKPF", "length": 140 }, "evidence": [ { "id": "G3MZM9", "url": "https://omabrowser.org/oma/group/G3MZM9/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "D3ZG05-1", "protein_name": "40S ribosomal protein S12", "gene_name": "LOC120100003", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MAEEGIAAGGVMDINTALQEVPKTALIHDGLARGICEAAKALDKRQGHLCVLASNYDEPMYVKLVAALCAEHQINLIKVDDNKKLGEWVGLCKIDREGKPRKVVGCSCVVVKDYGKESQAKDVIEEYFEYKK", "length": 132 }, "evidence": [ { "id": "G3MZM9", "url": "https://omabrowser.org/oma/group/G3MZM9/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "D3ZGM7-1", "protein_name": "Peptidase inhibitor 16", "gene_name": "Pi16", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MRNCRVSWMPQHSSAAVSGICPPQEGPWSSYSLWPEPPLLREKEAVAKDSRGVDSTLVQTQGTQPSWRHCVSWAGPPDTAPAAPPQPGWCLCGKDFKSSRQTPDRERQRGLATMHSSCSPWVMLPQLPLLLLLLLLLLTATGPATALTEDEKQTMVELHNHYRAQVSPPASDMLQMRWDDELAAFAKAYAQKCVWGHNKERGRRGENLFAITDEGMDVPLAVGNWHEEHEYYNLSTATCDPGQMCGHYTQVVWSKTERIGCGSHFCETLQGVEEANIHLLVCNYEPPGNVKGRKPYQEGTPCSQCPLGYSCVNSLCEPERKPEKAQDSPPRVTEVPGSRETGIPSLATSESLHFSSVTKVSDSLATEPSPAVETKAPPSLATEGPSSMATEAQSFLTEVPSVSATHIQPSLDEGPVNFLTSTHIPVPKSTDKEASSKSRAASVSPEKSLYPKMSPTETGESPPQIQEEAEPKAELPEREDELPEAEVELPEAEAELPEAKAELPVSSEALVPVLPAQERGGPKASLEHSSYPVPTYLPNFPSASGNATGGRTLALQSSRTGAEDPEKASWDSKNSAPVWGPFPGLLLPLLLLAGIF", "length": 596 }, "evidence": [ { "id": "G3MZM9", "url": "https://omabrowser.org/oma/group/G3MZM9/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "D3ZGX2-1", "protein_name": "C-type lectin domain family 2, member M", "gene_name": "Clec2m", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MQTESSLRLSQSSHHRLTFDLKKVVTLWILVIGVIAVLLWGFFSFPKKFTVTRQTKNEVCSDGVKICLHGWNKLNRNCFTHFSHANSWFTAKETCKFHDATLAVFNDQTELDIVMKQMEDIQTFWIGLYKKDFRGPWVWTNGSKYNNWYEVQDYGHCAFLHKSGIDSTNCNDLKEYICTQEGHCP", "length": 185 }, "evidence": [ { "id": "G3MZM9", "url": "https://omabrowser.org/oma/group/G3MZM9/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "D3ZIZ8-1", "protein_name": "Ferritin", "gene_name": "RGD1560203", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MAEASSQVRQNYDRCCEEAVNTHIRLLLQASYSYLSMAFYFDRDDVALENFKRFFLSKSHDCKASVEMFVFMQNKRGGHVFLPSIAKPDRKSWQGGFRAMECAFRMEMTINQSLLNLHELAKGKGDAHLCNFLGQHCLDQQVHVLKKIGGYLTNLRQMGAPEQALAEYLFDKLSLS", "length": 176 }, "evidence": [ { "id": "G3MZM9", "url": "https://omabrowser.org/oma/group/G3MZM9/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "D3ZKK4-1", "protein_name": "Zinc finger protein 869", "gene_name": "Zfp869", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MDTPIVGLSSPDQGLVSFEDLVVHFTQDEWDLLEASQKSLYGDVMLETFRNLTAVGYEWEDEAIEDHCEEPEVNLRDIVSHSEYTHEYEHKEYEEKPPDANFLTSVEGCVETKTSSGPSVCEVCLKTFGLYHLTYNGHHNYDYKELRGSQTEENDCEGNSCDKTSGSLQKEDKIHTGKKLYVCQECGKAFRYPSALQLHERIHTGEKPYECKDCGKAFRGLSALHLHERIHTGEKPYECKQCGRAFTYLSALQLHERIHTEERPCECKQCGKTFRYSRALKLHERIHTGEKPYECKQCGKFFRSHRTLKLHKRIHTGEKPYECKECGKAFRWLTSLKLHEKIHTGEKPYECQECGKAFRCQASYHRHKITHGGETLYECKECGKSFIYPSLLQVHERTHTGEKPFECKLCGKAFRCQSSLRLHERTHTGEKPYECKHCGKAFSSYNYLRFHERSHTGEKPYECKECGKTFTHRSYLRSHERRHTGEKPYQCIQCGRSFSRHSSFKRHQSVHGESPYEQYLIPLSPFSSKE", "length": 530 }, "evidence": [ { "id": "G3MZM9", "url": "https://omabrowser.org/oma/group/G3MZM9/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "D3ZKM3-1", "protein_name": "Protein GPR15LG", "gene_name": "Gpr15lg", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MRLLTLSGLFFMLFLCLCVLSSEGRKRPAKFPKLRPCCHLSPRSKPITWKGNHTRPCRPCRKLESNSWVVPGALPQI", "length": 77 }, "evidence": [ { "id": "G3MZM9", "url": "https://omabrowser.org/oma/group/G3MZM9/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "D3ZL22-1", "protein_name": "Olfactory receptor", "gene_name": "Or1x2b", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MSKWGENETGVIEFLLLGITNDPQQQRILFWAFLCMYLVTVAGNTLIFLAISSDPHLHTPMYFFLANLSFDDVCFTTNIIPRLLAGHVSGTETISYAYCLTQMYFLISFGNVDTFLLAAMALDRFVAICYPLQYHTIITPRLCVGLASVVWISSGLIALVHTLLMSRLTFCSSIPEISHFYCDAYLLMKLACSDTRINQLVFLGAVVFFVAPCILIVFSYVRIAMAVFQIPSAKGRHKAFSTCSSHLTVVILFYGTVLGIYIRPPDSFSTQDTVATIMFTVVTPMLNPFIYSLRNKDMKETVTRLLHRGSKSS", "length": 313 }, "evidence": [ { "id": "G3MZM9", "url": "https://omabrowser.org/oma/group/G3MZM9/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "D3ZLG9-1", "protein_name": "N-terminal Ras-GEF domain-containing protein", "gene_name": "AABR07047293.1", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MFSCCVWTTEGSGLKKDKNEGQGGTWKFMLLSCLQCLWPFAQKEIDLTRDNQAQDHEDQGEHEYAPQVVTEPCRESRISADMVENLVNRLVSSLQGGDPFFIPAFLYGYRQFTTTQHVLDRLLKRFAYFYLGCEEDEQIKSSLCCFLDTWIDQYPEEFSQTILKKLKTYLTVNMPSSDLNLRVHMLLKELRQESNESEGKDDDSVSLPVTLLYKTASAADLSSSVEVGSHTSGDLDIEVWFPSQKVQPEPAYPHETETPQSTIKVISWD", "length": 269 }, "evidence": [ { "id": "G3MZM9", "url": "https://omabrowser.org/oma/group/G3MZM9/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "D3ZMT2-1", "protein_name": "NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 3", "gene_name": "Ndufa3-ps1", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MAGRSSDFFKNAQAKEPVLVVSFSVWGLAVILPMISPYIKYAGVISKATPYNCPVPVRDNGNVPGVPSQPQERLSPSLERLKNL", "length": 84 }, "evidence": [ { "id": "G3MZM9", "url": "https://omabrowser.org/oma/group/G3MZM9/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "D3ZNA3-1", "protein_name": "60S ribosomal protein L7a", "gene_name": "AABR07049918.1", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MPKGKKAKGKKVAPAPAVVKKQETKNVVNPLFEKRSKNFGIGQDIQPKRDLTRFVKWPHYIRLQWQRAILYKQVKVPPAINQFLQALVRQTVTQLLKLAHKYRPETKQEKKQRLLAHAEKKAAGKGDVPTERPPVLRAGVNTVTTLVENKKAQLVVTAHDVDPIELVVFLPALCRKMGVPYCIIRGKARLGRLVHRKTCTTVAFTQVNSKDKGALAKLVEAIRTNYDDRYDEIRCHWGGNVLGPKSVARIAKLEKVKAKEFATKLG", "length": 266 }, "evidence": [ { "id": "G3MZM9", "url": "https://omabrowser.org/oma/group/G3MZM9/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "D3ZNR1-1", "protein_name": "Elongin-B", "gene_name": "Elobl9", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MEVFLMIRRKKTTIFIEAQELTTVLELKRIVQGILKRPPEEQLLFKDDQLLDESKTLRDCGFTSRVAKAQDPATVGLVFREDASEGLQIHPYSTPLLPSVMKTGTDSLE", "length": 109 }, "evidence": [ { "id": "G3MZM9", "url": "https://omabrowser.org/oma/group/G3MZM9/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "D3ZNU6-1", "protein_name": "Olfactory receptor", "gene_name": "Or5p66b", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MSWLENGNHTTVAEFLLLGLTDDPVLRVILFTIILCIYLVTVSGNLSTILLIRVSSQLHHPMYFFLSHLASVDIGYSSSVTPNMLVNFLVERNIISYLGCGIQLSLVAFFGAAECFLLAAMAYDRFMAICNPLLYSTKMSTQVCILLVVASYIGGFLNASFAMVSFCSFLFCGPNIINHFFCDFAPLIELSCSDVSVYVIATSFSAGSVTMITALVIAISYSYILITILKMHSTEGRQKAFSTCTSHLTAVTLFYGTVTFIYVMPKSSFSIDQNKIVSVFYLLVIPMLNPLIYSLRNNEIKSALKKQIWRKTVS", "length": 314 }, "evidence": [ { "id": "G3MZM9", "url": "https://omabrowser.org/oma/group/G3MZM9/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "D3ZPU6-1", "protein_name": "Large ribosomal subunit protein eL21", "gene_name": "LOC134485591", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MTNTKGKRRSTRYMFSRPFRKHGVVPLATYMRIYKKGDIVDIKGMGTVQKGMPHKCYHGKTGRVYNVTQHAEGIIVNKQVKGKILTKRINVRIEHIKHSKSRDSFLKRVKENDQKEKEAKEKGTWVPLKRQPAPPREAHFVRTNGKEPERLEPSPYGFMA", "length": 160 }, "evidence": [ { "id": "G3MZM9", "url": "https://omabrowser.org/oma/group/G3MZM9/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "D3ZQ96-1", "protein_name": "Large ribosomal subunit protein eL21", "gene_name": "LOC102550668", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MTNTKVKRRGTRYVFSRPFRKHGVVPLVTYMRLYKKGDIVDIKGMGAAQKGMTHKCYHGKTVRVYNVTQHAVGIIVNKQVKGKILAKRINVWIEHIKHSKSRDSFLKQVKENDQKKEEAKEKGTWVQLSLQPAPPREAHFVRTNGKEPELLEPVP", "length": 155 }, "evidence": [ { "id": "G3MZM9", "url": "https://omabrowser.org/oma/group/G3MZM9/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "D3ZQD9-1", "protein_name": "Developmental pluripotency-associated protein 3-like", "gene_name": "LOC120096627", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MDKSSEKVDPVVNPETQMNDGSQREDEEDSPDDSEILQPETLVKVMKKLTLNPSAKPPKYHRHQRVRLRIKSQPVGNRSERIMREVQSAFPKTRVRTLLSVLKDPIARMRRFVRIEQRQRQLEGNERRDEPFRCLCTFCHYQRWDPSENAKIGQNQKN", "length": 158 }, "evidence": [ { "id": "G3MZM9", "url": "https://omabrowser.org/oma/group/G3MZM9/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "D3ZQT0-1", "protein_name": "Glyceraldehyde-3-phosphate dehydrogenase", "gene_name": "AABR07071101.1", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MILCIKPSSTTKYCLNQCYLISCINKPNLLDGVNGIPLDIVAINDPFIDLNYVVYMFQYDSTHGKFNGTVKAENGKLVINGKPTTIFQERDLANIKWGDADAKYVMESTGIFTTMEKAGAHLKGGTKMVIISAPLADAPILKYDNSLKIVSNASYTTNCLAPLTKVIHDNFGIVEGLMTTVHTITATQKIVDGPSGKLWRGGHGAAQNINPETTGVAKAVGKVIPELNGKLTGIAFHVLTPNVSVVDLTCHLKKPAKYDDIKKVVKQASKGPLKGILGYTEDQVVSCDFNSNSHSSTFDARTGIALNDNFVKLISWCDNEYGYSNRVVDLMAYMASKE", "length": 338 }, "evidence": [ { "id": "G3MZM9", "url": "https://omabrowser.org/oma/group/G3MZM9/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "D3ZTK7-1", "protein_name": "Uncharacterized protein", "gene_name": "AABR07012426.1", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MSGDLEAKISGYTHISVQRFCYKWTISNFSFCMDGIRENITSPVFSLEGNEEVQWCLRIFPNGVDEESKDYLSVSLGLHSCPKSPVLAKVQFWIINAQGEKHQIKEIPNILSFSPKHQWGLRKFILREFLLSRRHGLLPEDQLILCCKVSVVGPSFSTPGHNMTPANKDPRQMLADDVGELWENSLFTDCSLVVAGQEFRAHKAILAARSPVFRAMFEHEMLESLTNRIEIHDIHLQVFKEMMAFIYTGKAPHLHSHSMATELLAAADMYDLQDLKVMCEDSLCRNLSVKTAVPTLMADLHSTELLKTRVMDFIILHASEVSETLEWKSMVESHPHLVEEAFGSLASMHYFFLEPSLKR", "length": 359 }, "evidence": [ { "id": "G3MZM9", "url": "https://omabrowser.org/oma/group/G3MZM9/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "D3ZV50-1", "protein_name": "Small ribosomal subunit protein uS4", "gene_name": "Rps9l1", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MLVARSWVCHKTYVTPRRPFEKSRLDQELKLIGEYGLRNKHEVWRVKFTLAKIRKAARELLTLDEKDPRRLFEGNALLRRLVRIVVLDEGKMKLDYILGLKIEDFLERRLQTQVFKLRLAKSIHHAHVLIRQRHIRVRKQVVNIPSFIVCLDSHKHIDFSLRSPYGGGRPGRVKRKNAKKGQGGAGAGDDEKKEK", "length": 195 }, "evidence": [ { "id": "G3MZM9", "url": "https://omabrowser.org/oma/group/G3MZM9/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "D3ZWL0-1", "protein_name": "Ribosomal protein L32 like 1", "gene_name": "Rpl32l1", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MAALQPLVKLKIVKKRTKKFIRHQSDRYVKIKRNWRKPRGIDNRVRRRFKGQILKPNIGYGSNKKTKHMLPSGFRKFLVHNVKELEVLLMCNKSYCAEIAHNVSSKNRKAIVERAAQLAIRVTNLNARLRSAENE", "length": 135 }, "evidence": [ { "id": "G3MZM9", "url": "https://omabrowser.org/oma/group/G3MZM9/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "D4A176-1", "protein_name": "Golgi associated RAB2 interactor 5A", "gene_name": "Garin5a", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MPRLRTSARSPAPAVRMAISPSGPLGFTSPVTQPRREASPGVPTTQGRGVAMKGGRDLKPASGRADRPLAQAYAPCRPGRLQRHLLSGEFDQLRDFPIFESNFVQVTRFGEVANKVTMGVAASSPALELPDLLLLAGPDKENGHLQLLGLFPLQFVQLFVHDVSRQQLKVKFRTGRAFYLQLRAPPETRDCEFGRWVRLLYRLRFHSPTCAVPFTHEDTVPEESEDEDEVEEGQLQPPEVRAGPRAQGCWARKDGKGPVSCHRGQTRPAGLRTLGALIQPRSFQITKGPEIKPAQLRAREMDF", "length": 303 }, "evidence": [ { "id": "G3MZM9", "url": "https://omabrowser.org/oma/group/G3MZM9/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "D4A9N2-1", "protein_name": "Olfactory receptor", "gene_name": "Or4a77d", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MGQNNSVSEFILLGLTEDPAGQKTLFVVFLLIYIGTMVGNLLIVWTVIASPSLDSPMYFFLAYLSLIDALYSSTILPKLLIDLLCDKKTISLTACLVQLFVEHLFGGVEIFLLVFMAYDRYVAICKPLYYLTIMNQRVCVCLVVVSWIGAFAHALVQVFSVYKLPFCGPNIIDHFACDMYPLLGLACTDTYFLGLTVVGNNGAISVVVFMLLLLSYGIILNSLKTHSQEGRRKALSTCSSHIMVIVLFFVPCIFMYVRPVSNFPLDKFITVFYTVFTPMLNPLIYTLRNLEIKKSMEKLCRKIFTSDRIRISSCYS", "length": 316 }, "evidence": [ { "id": "G3MZM9", "url": "https://omabrowser.org/oma/group/G3MZM9/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "D4AAM5-1", "protein_name": "Preferentially expressed antigen in melanoma-like", "gene_name": "Pramel", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MDVKTPNKLLELAIHSLLNEESAAIQALEEIPRELFVPLFIAAFEGGHKNVLSAMVKVWPYYCLHIGSLSIQEPQHELLKAMIENLPVYPAPSSSSRGPKLRILDLRQDTDCRITCPEVSTKTPSCFYSCAYSDRSITKIERQLCCVNAECKTLLPRPVELLVDLSLDGSLMEKEFLVLLMYKIEESLGSLHVCCRDLQIDKLCKCKCTLKFLDLKCIDQLSVDRGSLSDITSILCRMIHLESLSLSNVTFRSLSGKVFKIFLSHLQRMEHLKELSLSSFCLKNHLDRVLRILPPGLDFLYLPFCDLSYRDFKFMSQSPQVTHLKLLNLSNNPMYWGDFEPFHTVLINLSGTLQHLEINHCLISDSAMSALIPALIRCTRLRVLGFASNPISMPMLVNIMHNLTPMKELKYVIYPIPVHCYERWHFQGSLDRQKLAIVQLQLKAMLELAHREDMNWITYCE", "length": 461 }, "evidence": [ { "id": "G3MZM9", "url": "https://omabrowser.org/oma/group/G3MZM9/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "D4AAN9-1", "protein_name": "Similar to human chromosome 6 open reading frame 52", "gene_name": "C17h6orf52", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MVETQSPGKECAVLPLWVLTVTSCPLPSAIREQLRVHHSLRCHRDNHYELLHSFYWLSCYSRGSTLSGNGLGPLCVTENPELLAGPWAIPEETTDPAENQEEDFLRDPNLHLNIEESDKEFMAVREELYDSLMNRRWHCLDTVLSNVPDELPQCEVF", "length": 157 }, "evidence": [ { "id": "G3MZM9", "url": "https://omabrowser.org/oma/group/G3MZM9/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "D4ABB6-1", "protein_name": "Olfactory receptor", "gene_name": "Or13a27c", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "VNCIWHSKMVSPNQTVVTEFVLQGFSEHPSLRLFLTGCFMSLYTIALMGNIVIIALVTSSTGLHSPMYFFLCNLATMDIICTSSVLPKALVGLLSEENTISFKGCMTQLFFLVWSGSSELLLLTVMAYDRYVAICAPLHYSSRMSPQLCGALAMGVWSICAANASMHTGLMARLSFCGPKVITHFFCEIPPLLLLSCSPTYVNSIMTLIADAIYGGINFVLTLLSYGCIIASILRMRSAEGKRKAFSTCSSHLIVVAMYYSSVFFAYISPGSSYNPERSKFTSVLYSVLSPTLNPLIYTLRNKDVKLALGRILASFSH", "length": 318 }, "evidence": [ { "id": "G3MZM9", "url": "https://omabrowser.org/oma/group/G3MZM9/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "D4ADX2-1", "protein_name": "Olfactory receptor family 4 subfamily A member 80", "gene_name": "Or4a80", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MGQSKIVTEFVLLGFTQDPAGQKALFVMFSLMYIATMVGNLLIVGTVIVSPSLGSPMYFFLASLSLMDAVYSTAISPKLIVDLLREKKTISFRACISQLFIEHLFGGVDIVILVAMAYDCYVAICKPLHYLIIMNRRVCILFLVMAWAGGFAHALFQVLAVYNLPFCGPNIIDHFGCDIYPLLLLACTDTYLIGLTIIANGGAMCIVIFILLLLSYAIILRSLQNHSQEGRHKALSTCSSHITVFFLFFVPCILMYVRPVSSFPIDKSITVIYTVVTPVLNPLIYTLRNSEMKNSMEKLLQKILSPNRLRLLCCLYY", "length": 317 }, "evidence": [ { "id": "G3MZM9", "url": "https://omabrowser.org/oma/group/G3MZM9/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "D4AEJ6-1", "protein_name": "Peroxisomal biogenesis factor 11 gamma", "gene_name": "Pex11g", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MALLNGLASALESYRGRDRLVRGSVGPWRDRSDLEFGQDSEMRKTGQRGGPKGTDIGRLVSYMRTSYLSLPNCWPYKCVLALQIRTLGYGCQLIGGVLVEQCPSRSEVGRRLLVVSAQLSHCRTVLRLFDDLAMFVYTKQYGLGAEEEDVFIRWLSVLSNMADQLYYPCEHVAWAADAKVLQVDSARWWTLSTAFWSLSLLLGAVKSLWTMLKLRQKLRSPTGHFASQLPRSKWRAVEARIWSEALTLLSNLADLANAVHWLPPGVLWAGCFPPWLVGLMGTISSILSVYQAARAGKQAEVDSP", "length": 304 }, "evidence": [ { "id": "G3MZM9", "url": "https://omabrowser.org/oma/group/G3MZM9/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "D6R901-1", "protein_name": "Ubiquitin carboxyl-terminal hydrolase 17-like protein 21", "gene_name": "USP17L21", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MEEDSLYLGGEWQFNHFSKLTSSRPDAAFAEIQRTSLPEKSPLSCETRVDLCDDLAPVARQLAPREKLPLSNRRPAAVGAGLQNMGNTCYVNASLQCLTYTPPLANYMLSREHSQTCHRHKGCMLCTMQAHITRALHNPGHVIQPSQALAAGFHRGKQEDAHEFLMFTVDAMKKACLPGHKQVDHHSKDTTLIHQIFGGYWRSQIKCLHCHGISDTFDPYLDIALDIQAAQSVQQALEQLVKPEELNGENAYHCGVCLQRAPASKMLTLLTSAKVLILVLKRFSDVTGNKIAKNVQYPECLDMQPYMSQPNTGPLVYVLYAVLVHAGWSCHNGHYFSYVKAQEGQWYKMDDAEVTASSITSVLSQQAYVLFYIQKSEWERHSESVSRGREPRALGAEDTDRRATQGELKRDHPCLQAPELDEHLVERATQESTLDHWKFLQEQNKTKPEFNVRKVEGTLPPDVLVIHQSKYKCGMKNHHPEQQSSLLNLSSSTPTHQESMNTGTLASLRGRARRSKGKNKHSKRALLVCQ", "length": 530 }, "evidence": [ { "id": "G3MZM9", "url": "https://omabrowser.org/oma/group/G3MZM9/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "E0CXP6-1", "protein_name": "UMAP1-MVP12 associated (UMA) domain containing 1", "gene_name": "Umad1", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MFHFFRKPAESKKPSGPEPEADGFVLLGATANEVRCKTSEAEGSQALETGKEDTSSVTVSGPETENQTGQTLQNNSLTAELLSDVPFTLAPHVLAAQGTISDLPDHVLSYDVGDNLSRFWYDFTLENSVLCDL", "length": 133 }, "evidence": [ { "id": "G3MZM9", "url": "https://omabrowser.org/oma/group/G3MZM9/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "E0CZF1-1", "protein_name": "PRAME like 34", "gene_name": "Pramel34", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MSGQTPPTHTLLTHEALIMSSLEELPTVVFPALFKEAFAGRHTNLLKAMVAAWPFPCLPVGPLMKKPNLETLQALLDGIDMRLTREFHPRRAKLQVLDMRNMYHAFWNIRADANDSDCKSKTLDEKQLVKVLPRYARRQRLKVIVNLSISSHFNKSKAYFLNWAKQRIGSLYFCCIKMRIWDPPDQVIRDIFNVFDPEHITELELNTDWTLLQLAHFASYFGHMKNLQKVFLAPLHKNTSPIINITNATEAKCVHKIISQFSQFNCLQHIFMKHVHFLRDYMNQVLGCLMTPLETLSITQCLISQRDFDLFSCSQNLFKLKHLEIRGMILYALDLMPLRVLLEKVADTLEILDFQWCRMKDSQINALLPALSQCTQLNQINFYNNDFSMCTLKALFQHTANWSKMNVEQYPAPLQCYSELGHVSVERFVQLCQELMYTLRAIRQPKSISFATDNCQKCGKPCVYDQGPILCSCFQ", "length": 475 }, "evidence": [ { "id": "G3MZM9", "url": "https://omabrowser.org/oma/group/G3MZM9/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "E1B8K9-1", "protein_name": "40S ribosomal protein S6", "gene_name": "", "tax_id": 9913, "organism": "Bos taurus", "sequence": { "sequence": "MKLNISFPATGCQKVIEVDDERKLRTFYEKRMATEVAADTLGEEWKGHVVRISGGNDKQGFPMKQGVLTHGRVRLLLSKGHSCYRPRRTGERKCKSVRGCIVDANLSVLNLVIVKKGEKDIPGLTDTTVPHRLGPKRASRIRKLFNLSKEDDVRQYVVRNSLNKDGKKPRTKAPKIQRLMTPRVLQHKRRRIALKKQRTKKNKEEAAEYAKLLAKRMKEAKEKRQEQIAKRRRLSSLRASTSKSESSQK", "length": 249 }, "evidence": [ { "id": "G3MZM9", "url": "https://omabrowser.org/oma/group/G3MZM9/", "database": "OMA" } ], "glygen_name": "Bovine", "common_name": "Bovine" }, { "uniprot_canonical_ac": "E1BBD9-1", "protein_name": "RNA polymerase II subunit A C-terminal domain phosphatase SSU72", "gene_name": "LOC112445820", "tax_id": 9913, "organism": "Bos taurus", "sequence": { "sequence": "MPFLPLRLAVVCSSNQNRSMEAHNILSKRGFSILSFGTGTNMKLPGPARDRPNVYDFRAMYDDVYKDLLRKDKERYMQNGVLRMLERNMEKEMPRPERFQECKDLFDLILTCEERVYDQVVEDMNSGEQETCQPVHVINVNILDTNKEATLGAFLICDLCQCVQLMGDMEDRIGELLQAFEEKSGRSFLHTVCFY", "length": 195 }, "evidence": [ { "id": "G3MZM9", "url": "https://omabrowser.org/oma/group/G3MZM9/", "database": "OMA" } ], "glygen_name": "Bovine", "common_name": "Bovine" }, { "uniprot_canonical_ac": "E1BLY1-1", "protein_name": "Small ribosomal subunit protein uS8", "gene_name": "", "tax_id": 9913, "organism": "Bos taurus", "sequence": { "sequence": "MVRMNVLADALKSINNAEKRGKRQVLIRPCSKVIIRFLTVMMKHGYIGEFEIIDDHRAGKIVVNLTGRLNKCGVISPRFDVQLKDLEKWQNNLLSSRQFGFIVLTTSAGIMDHEEARRKHTGGKILGFFF", "length": 130 }, "evidence": [ { "id": "G3MZM9", "url": "https://omabrowser.org/oma/group/G3MZM9/", "database": "OMA" } ], "glygen_name": "Bovine", "common_name": "Bovine" }, { "uniprot_canonical_ac": "E7F638-1", "protein_name": "Moesin b", "gene_name": "msnb", "tax_id": 7955, "organism": "Danio rerio", "sequence": { "sequence": "MSINVRVTTMDAELEFAIQSSTTGKQLFDQVVKTIGLREIWYFGLQYQDSKGFSTWLKLNKRVTAQDVRKENPLLIKFRAKFYPEDVAEELIQEATQRLFFLQVKEAILNDDIYCPPETAVLLASYAVQMKHSDYNSEHHIPGYLCRDKLLPQRVLEQHKLTKEQWEQRIQVWHEQHKSMSREDAMIEYLKISQDLEMYGVNYFSIKNKKGSELWLGVDALGLNIYERSDKLTPKIGFPWSEIRNISFNDKKFVIKPIDKKSPDFVFYAPRLRINKRILALCMGNHDLYMRRRKPDTIEVQQMKAQAREEKNKRQQERALLENEKKRRENAEKETEKIARETMELMERLRQIEEQTKKAQEELEEQTKRALELERERKFAQEEAEKLEKDRRIAEDVKTALLQQSENQTKNKDNLATELAELTSKINLLEDAKKKKEDEARKWQRRAIMVEVDLEKTKEELKSKLIGVHIQATSQTENDHDENDESSAEASAELTSTGSFRDRSEEQRITETEKNEPLQKRLQALSSELADARDDSKKTANDLIHAENVRLGRDKYKTLRQIRQGNTKQRIDEFESM", "length": 577 }, "evidence": [ { "id": "G3MZM9", "url": "https://omabrowser.org/oma/group/G3MZM9/", "database": "OMA" } ], "glygen_name": "Zebrafish", "common_name": "Zebrafish" }, { "uniprot_canonical_ac": "E7FA22-1", "protein_name": "Protein tyrosine phosphatase type IVA 3", "gene_name": "ptp4a3b", "tax_id": 7955, "organism": "Danio rerio", "sequence": { "sequence": "MAWLNGLYPVEVCYNSMRFVITHNPTNQTLDTFIEDLKRYDAKTVVRVCESTYDKTPLEKHGITVMDWPFDDGAPPPTKIVDDWISLLKKSFSEDPGCCVAVHCVAGLGRAPVLVAVALIEGGMKYEEAIHLIRLKRHGAFNSKQLTYLEKYRSKKRLRFKDPFKHRSKCWLM", "length": 173 }, "evidence": [ { "id": "G3MZM9", "url": "https://omabrowser.org/oma/group/G3MZM9/", "database": "OMA" } ], "glygen_name": "Zebrafish", "common_name": "Zebrafish" }, { "uniprot_canonical_ac": "E7FE27-1", "protein_name": "Beta-1,4-N-acetylgalactosaminyltransferase", "gene_name": "b4galnt4b", "tax_id": 7955, "organism": "Danio rerio", "sequence": { "sequence": "MRMRFPLKKIRKQFKLLLLLVLLMFAIGFTYLHINQGKAIKLHFNYGKDMERQAEGIGSSPKKHLSSSINPFEHGDAADSQEDGWGGEELNESAQESRANAEMHTLLAQKFLGLPWKPEYKGQANLHVFEDWCGSSVSQLRKNLHFPLYPHTRTTVKKIAVAPKWKNYGLRVFGFIHPYKDGDFQFAIASDDNSELWLSSDESPLNARLLVYVGQHGSEWTAPGEFSKFRSQTSKPVRLMSSRRYYFEVLHKQDDRGSDHVEVGWRPFLPGQKFDVIDSAYISLYTDESSLKMNSVHHIPQTLASHSLALQIYHRTETHTADMLKPDPRDTFYKIPMIDQSRLENVLPSCVYSPTYVVKDFPIARYQGLQFVYLSYVYPNDFTRLTHMEKTNKCFYRESPVYLEKFGFYKYMKMDEEEDDQPVFFPKPDDFLEEEEGVDPEEAINSSNRPVKRSGPSYQTSRITAATASSKPDRLDGGSKSSVFQQEKQYVQFKEQERSKKRTKGERFYRHSQVVDDEMTEIRQVKGSTGVLESQSGSLNEQTGPSEENGDSQTLSLVQRGRSLAWVLPDPALQSESKLIETASPTVKERSPFKLPHLYVLANRILGNAGKPVVEKESNSNKIYITRPRPPVSRPKPPVEVFPGVFLYQSRKSKRLVDLSSKWRSLKTQAAASAPWANFPLMDHKTSTQSALLKQSHLSSPTEPGPHNKGDPTASISDPDSVPPSSSEKRDHPGLNSSSQPPEEEPTKISEMAEGLDVAPQSRGLEEGEMSEYSYEEAEVRPHLAEEAINWQRTFSVNPVDFELLRSDWNDLRCNVSGNLQLAENEVIDVISQFMERLNERNRGIYTLARIVNVEKRRDSARGNRYLVELLLMEGGKRLVRLSEYIYLLLHRSRFEEGIESREGTVPSSHRTPSKIPLPSGSSAQTHTTTPWSTSWAKPLLCQPIMLQWRHDVMVHFVVPVKNQARWVQQFISDMELLHRETKDENFSVIIVDFQSDDMDVEQALKESTVPRYEYLKREGNFERSSGLQMGVDTIEDSHSIVFLCDLHIHFPHNILESIRKHCVEGRLAFAPIVMRLDCGSSPLEPDGFWEVNGFGLFGIYKSDFDKIGGMNTEEFKDHWGGEDWELLDRVLQNGLEVERLRLRNFYHYFHSKRGMWNVPVKRASQG", "length": 1167 }, "evidence": [ { "id": "G3MZM9", "url": "https://omabrowser.org/oma/group/G3MZM9/", "database": "OMA" } ], "glygen_name": "Zebrafish", "common_name": "Zebrafish" }, { "uniprot_canonical_ac": "E7FFR8-1", "protein_name": "Ubiquinol-cytochrome c reductase complex assembly factor 5", "gene_name": "uqcc5", "tax_id": 7955, "organism": "Danio rerio", "sequence": { "sequence": "MLRKSQNLKYMLSLVPGKKRFGVYRFLPVFFCIGGVMEWIMINVRIGRETFYDVYRRKQSERAYQQKTEEGLIMLTDSQAK", "length": 81 }, "evidence": [ { "id": "G3MZM9", "url": "https://omabrowser.org/oma/group/G3MZM9/", "database": "OMA" } ], "glygen_name": "Zebrafish", "common_name": "Zebrafish" }, { "uniprot_canonical_ac": "E9PUW9-1", "protein_name": "Vomeronasal type-1 receptor", "gene_name": "Vmn1r143", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MSAHGKSVKTTEEVALQILLLCQFGVGTVANVFLFFHNFSPVLTGSKQRPRQVILSHMAVANALTLFLTIFPNNMSAFAPKTPPNELKCKLEFFSHMVARSKNLCSTCVLSIHQFVTLVPVNRGKGKLILRASVPNLWNYSCYSCWFYSVLSNIHIPIKVTGPQITDNNTDSKSNLFCSTSGFIVGMVFLQFSHDATFMSIMVWTSVSMVLLLHRHRQRMQHILTPNQDARGQAETRATHTILMLVVTFVSFYLLNCICIIFHAFSIHSRLFIRLVSEVLAAVFPSICPLLLIFRDPKDPCSVLFKC", "length": 307 }, "evidence": [ { "id": "G3MZM9", "url": "https://omabrowser.org/oma/group/G3MZM9/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "E9PUZ0-1", "protein_name": "Apolipoprotein L 11b", "gene_name": "Apol11b", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MDWNEISEDIRKVECRTFEKVIDNATEDLITDLRSLITEDGAWNGFVEAVELSSEEGEALRDALKERLAQDPTDENDRPQREQQKERFLREFPQLKKKLEDHIRKLRDLADKFDQVHKDCTISNVVSTSASAASGVLALLGLVLSTVTAGASLALSASSVALGATSSVSSFTTTVVEDSMTLSYESEARNLIGASMNVLEEILSIMPKITCKFYNTVADLVKAFKTLKGQIQTIRRARSISRRGAQARNLTSTGRSSGQGVSQMTRGARIRAGVFTSVFLGWDVYDLVTKQRICMMGEKQSQVEHCGTWLASWRRTFRNLSRSTMLCSQTCLSDALP", "length": 337 }, "evidence": [ { "id": "G3MZM9", "url": "https://omabrowser.org/oma/group/G3MZM9/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "E9PV04-1", "protein_name": "Eukaryotic initiation factor 4A-III", "gene_name": "Eif4a3l1", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MATTTRMATSGSARKRLLKEDGMTKVEFETSEEVDATPTFDTMGLREDLLRGIYAYGFEKPSAIQQRAIKQIMKGRDVIAQSQSGTGKTATFSISVLQCLDIQVRETQALILAPTRELAVQIQKGLLALGDYMNVQCHACVGGTNVGEDIRKLDYGQHVVAGTPGRVFDMIRRRSLTTRAIKMLVLDEADEMLNRGFKEQIYDVYRYLPPATQVVLVSATLPHEILEMTNKFMTHPIRILVKRDELTLEGIKQFFVAVEREEWKFDTLCDLYDTLTITQAVIFCITKRKVDWLTEKMREANFTVSSMHGDMPQKERESIMKEFRSGASRVLISTDVWARGLDVPQVSLIINYDLPNNRELYIHRIGRSGRYGRKGVAINFVKNDDIRILRDIEQYYSTQIDEMPMNLADLI", "length": 411 }, "evidence": [ { "id": "G3MZM9", "url": "https://omabrowser.org/oma/group/G3MZM9/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "E9PVP9-1", "protein_name": "Predicted gene 4884", "gene_name": "Gm4884", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MSENLQSSPFFGTESTLHPSLPLLSNSKQPAGTVCNFSRVSTPDVSSAWLLPSASSTSLQPLMVVQMETSLGLPPSGQTYCQLQSPELCNTCVQVSQIRPPAVNGDKALTAPIHSPSQFLALPPAPSLEQPENKTMPEIKEGTKENQDTPVLTLEHPDLQQPLHCTDTESLRQKPDSDNAHLGCICMGPKELVGLENEIGSSFDFKDITRFGADIQLPQLLNTLTDIDQDQSCENWRVTSGLFDQVRENKHKSFELLEGAPQAKFQHWDLVEGEGAVGVAGASDRAIDNMAKHPEGKAPKGPPSKNRRARKQEQERPSGPENKSKKTQELKQSRNRVKAEKEPSIPKTKRKRNPPELSQNSFKKPRTNLAMHMLESVQVFHPLGKKSEKKTGISSFRGLRTFTSNKDSGPGSVTTTVLNMPCESQGPPKSPGKVQSAESSVGKDCLSPSQYELPPAGKVKLVPLPFPTLDKPQSRPASRKPLSLALRRPTAVYPVQHHSHSVQPTTLRPAQPPPASSSLIASAKPAPPISSSATGPNVTNPNQSSAVPQLATSRPVPYRASSHTSFQRELVSAARNKVPSPPRPVPYRASSNTSFQRELVSAARNKVPSPPKPQTQYLLHDFSRQPIPWKKVDILGPVVSQPITKEQRPEREAMKRRSQQERENAVKNPSTGKLQIFLQRERDMEISQYYGYAM", "length": 694 }, "evidence": [ { "id": "G3MZM9", "url": "https://omabrowser.org/oma/group/G3MZM9/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "E9PVW0-1", "protein_name": "Major urinary protein 8", "gene_name": "Mup8", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MKMLLLLCVGLTLVCVHAEEASSTGRNFNVEKINGEWHTIILASDKREKIEDNGNFRLFLEQIRVLENSLVLKVHTVRDEECSELSMVADKTEKAGEYSVTYDGFNTFTIPKTDYDNFLMAHLINEKDGETFQLMGLYGREPDLSSDIKERFAQLCEEHGILRENIIDLSNAMDLVPEHVLVLTRQIAASRPENEEWPEPPVLSGDFSPGLHHHPFLSIQHPQYKFCDLHSILSH", "length": 235 }, "evidence": [ { "id": "G3MZM9", "url": "https://omabrowser.org/oma/group/G3MZM9/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "E9PVZ7-1", "protein_name": "Olfactory receptor", "gene_name": "Or8b3b", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MKYFCLPRFSIISMLTGNGSFVTEFVLAGLTDRPELQLPLFYLFLIIYTVTVVGNLGLIILIGLNPHLYTPMYYFLFNLSFIDLCYSSVSSPKMLMNFVFEKNSISYEGCMTQLFFFLFFVISECYMLTSMAYDRYVAICNPLLYKVTMSPQVCSMLSFASYGMAFAGASAHTGCMLRLIFCNANVINFYLCDILPLLQLSCTSTYVNEVVVLIVVGINITVPSFTILISYVFILANILNIKSTQGRSKAFSTCSSHIMAISLFFGSGAFMYLNHSGSMNQGKISSVFYTNVVPMFNPLIYSLRNKDVKIALKKVMMRVHSRFIS", "length": 325 }, "evidence": [ { "id": "G3MZM9", "url": "https://omabrowser.org/oma/group/G3MZM9/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "E9PW18-1", "protein_name": "Vomeronasal type-1 receptor", "gene_name": "Vmn1r257", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MSVHDKSVKTTEEVALQLLLLCQFGVGTVANVFLFVHNFSPVLTGYKQRPRQVILSHMAVANALTLFLTIFPNNMMAFAPKTPPNELKCKLESFSRLVARSTNLCSTCVLSIHQFVTLFPLSRGKGKLILRASVQNLASYSCYSCWFFSVLSNIHIPIKVTGPQITDNNTDSKSNLFCSTSGFIVGIVLQFAHDATFMSIMIWTSVSMILLLHRHCQRMQDILTPNQNPRGQAETRATRTILMLVVTFVSFYLLNCICIIFHAFFIHSRLFIRLVSEVLAAVFPSICPLLLIFRDPKDPCSVLFKC", "length": 306 }, "evidence": [ { "id": "G3MZM9", "url": "https://omabrowser.org/oma/group/G3MZM9/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "E9PW59-1", "protein_name": "Olfactory receptor", "gene_name": "Or8b50", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MALANGSFVTEFILLGLTDQPDLQMPLFLIFLIIYLITAFGNLTLIILIVLNSHLHTPMYFFLFNLSFIDLCYSSLITPKMLMNFVLEKNIISYMGCMTQFYFFGFFAISECYVLTAMAYDRYVAICNPLLYSVAMSPKMCSYFILGSYFMGFSGAMIHTGCVMRLTFCDGNTINHYFCDLLPLLQLSCTSTYVNEIELFIVTGKDIIVPTVIIFASYGFILSNILKIRSTSGRSKAFSTCSSHIIAVSMFFGSSAFMYLKPSSAVSMNEAKFSSIFYSIVVPMMNPLIYSLRNKDVKVGLKKTLSRMFSHNLISL", "length": 316 }, "evidence": [ { "id": "G3MZM9", "url": "https://omabrowser.org/oma/group/G3MZM9/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "E9PXC3-1", "protein_name": "Cytochrome P450, family 2, subfamily c, polypeptide 69", "gene_name": "Cyp2c69", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MDPFVVLVLCLSFMLLLSLWRQRSARRNLPPGPTPLPIIGNYHLIDMKDIGQCLTNFSKTYGPVFTLYFGSQPIVVLHGYEAIKEALIDHGEVFSGRGSFPFFDKVSKGKGIGFSHGNVWKATRVFTVNTLRNLAMGKRTIENKVQEEAQWLMKELKKTNGSPCDPQFIIGCAPCNVICSIVFQNRFDYKDKDFLSLIGKVNECTEILSSPGCQIFNAVPILIDYCPGRHNKFFKNHTWIKSYLLEKIKEHEESLDVTNPRDFIDYFLIQRRQDKGIEHMEYTIEHLATLVTDLVFGGTETLSSTMRFALLLLMKHTHITAKVQEEIDNVIGRHRSPCMQDRKHMPYTNAMVHEVQRYVDLGPTSLVHEVTCDTKFRNYFIPKGTQVMTSLSSVLHDSTEFPNPEVFDPGHFLDDNGNFKKSDYFVPFSAGKRICVGESLARMELFLFLTTILQNFKLKPLVDPKDIDTTPKYSGFSKIPPKFQMCFIPVE", "length": 491 }, "evidence": [ { "id": "G3MZM9", "url": "https://omabrowser.org/oma/group/G3MZM9/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "E9PXM9-1", "protein_name": "F-box and WD-40 domain protein 24", "gene_name": "Fbxw24", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MEIHLSSFPMMEIFSYLDAYSLLQVAQVNKNWNALASNDFLWRKLCQERWLFCDMVTLQLLGKETWKQFFVYRTWQEHVKSRAIPEDFTYKEIPLECGVRGYAGYISGCALTRNGQGKSVVCMVSSKNKISTWDISESVITWVSPVQPASIKLLTTLPDMHIAVTVDIQSTIKLWDCHNREALATNNLESPCKSLKAVISKDGPIVLAGDILGNLYIFRIPDLHLISTVNVFPCGFDKIDCSPQKKWVLLSQNHPCIYPKVFYMSSLLRTSEFSDPVSTVLEFSLCKRAFWTPRREDRITLMSRRGRPIVTRFETFDMKLEENGNKTIVKGDLVASFSLQDYNENPKWMGVSDKSVIVCSTGSSLLLFSMKGLHLQTFQYSPEMIVRLWVDPVHVIITCNDGSIDVYMWEERSLLLKMCYRLQNGRHLPPFGFIKNLLCDDVSIVQLMIDRQGPCFLMAYTLNICS", "length": 466 }, "evidence": [ { "id": "G3MZM9", "url": "https://omabrowser.org/oma/group/G3MZM9/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "E9Q069-1", "protein_name": "Vomeronasal type-1 receptor", "gene_name": "Vmn1r157", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MSAHGKSVKTTEEVALQILLLCHFEVGTVANVFLFVHNFSPVLTGYKQRPRQVILSHMAVANALTLFLTIFPNNMMAFAPKTPPTELKCKLEFFSHMVARSTNLCSTCVLSVHQFVTLVPVNRGKGKLILRASVPNFANYSCYSCWFFSVLSNIHIPIKVTGPQIIDNNTYDKSNLFCSTSGFIVGIVFLQISHDATFMSIMVWTSVSMVLLLLTPNQDARGQAETRATHTILMLVVTFVSFYLLNCICIIFHAFSIHSRLFIRLVSEVLAAVFPSICPLLLIFRDPNDPCSVLFKC", "length": 297 }, "evidence": [ { "id": "G3MZM9", "url": "https://omabrowser.org/oma/group/G3MZM9/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "E9Q0V3-1", "protein_name": "Vomeronasal type-1 receptor", "gene_name": "Vmn1r68", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MGVAIIKENQTQSKMDFWNMGIKILFLSQTTTGILGNFSLIIYYVVNYIVHTLKPTDLILMHLMTSNALMVLSTGVLHTMAAFGLAHLLNDLGCRLILYIQRVGRSTSIGTICLLSIFQAITISHRVSCYKGQKIKSSKYIGYSISLLWVLHMFLNFILFVDIFIKRNRNNMTSDRDFKYYSIVERNEFSDSLYVALVVCPEIFSSVLITCSSGSMIGILYRHKQRVQHIRSFHVSSRNSPEWRATQNILVLVSTFLAFYTLSSVLQGCIALLNNPNWWLVNITRLTSLCFPTFAPCVLMSHYSFMPRFSLVWTWNKTS", "length": 319 }, "evidence": [ { "id": "G3MZM9", "url": "https://omabrowser.org/oma/group/G3MZM9/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "E9Q1C7-1", "protein_name": "Spermatogenesis associated glutamate (E)-rich protein 4A2", "gene_name": "Speer4a2", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MWMGETREGRKDADLPSKSNEGRRRWTWRMWMAHRQKTSPVPVTSKKQFEKEEKELIKKIQLTTEETNELRDRLIYVTEGSMNKRPYHRQTRHYKELKLKEKEIMTFLHNLEMENMEARENKQELKKEKNFYRNLHTRILLEENLIKKKLAILQQESKEIHADWAIIHQRLVELNLSGKDEQEKTSNLETQEHQVSEAARELGLATAEEDSILQNELPCQEAPAEHHPQHPPSSSDESSSDESSYSTCPEWE", "length": 252 }, "evidence": [ { "id": "G3MZM9", "url": "https://omabrowser.org/oma/group/G3MZM9/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "E9Q1N7-1", "protein_name": "Predicted gene 8126", "gene_name": "Gm8126", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MFSWLRRLFHRENGNQGETRPRQKESAIPSCKNRRMKSFWGRHMSAGKTSSQNCNITNHMKNRNKLDDMKFYIRKINAERLELFRILDIDMNTDLNYRMNIEFTIIKSQHEKTMLDMEKITQSINDTIEKYKEFIEDKDSYSFMHTYLLKECNQLKEKVRMLLNENRKLLVEQADQEASYGEENRFCHESSKNIHPKY", "length": 198 }, "evidence": [ { "id": "G3MZM9", "url": "https://omabrowser.org/oma/group/G3MZM9/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "E9Q328-1", "protein_name": "RIKEN cDNA 5430401F13 gene", "gene_name": "5430401F13Rik", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MASSRILLVLLSIALLALTSAQRVNEDDGSALQEEDALEIGDSNQQHDDIHERLNEIKNHFQDQISQHGKEAIKSKKGKNGPRSRRSSDDDNLEVQDHQSGNEQAGGGQGGRGRSELKGQNGKGSQKGKKGKGGQQEQKGKGGQQKQKGKGGQKTKRGKGGQRSQQDNVQEVYQE", "length": 175 }, "evidence": [ { "id": "G3MZM9", "url": "https://omabrowser.org/oma/group/G3MZM9/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "E9Q346-1", "protein_name": "Vomeronasal type-1 receptor", "gene_name": "Vmn1r160", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MSAHGKSLKTTEEVALQLLLLCQFGVGTVANVFLFVHNFSPVLTGSKQRPRQVILIHMAVANALTLFLTIFPNNMSAFAPKTPPTELKCKLEFFSHMVARSTNLCSTCVLSIHQFVTLVPVNRGKGKLILRASIPNLWNYSCYNCWFYSVLSNIHIPIKVTGPQITDNNTDSKSKLFCSTSGFIVGMVFLQFAYDATFMIIMVWTSVSMVLLLHRHRQRMQHILTPNQNPRGQAETRATRTILMLVVTFVSFYLLNFICIIFHAFSIHSHLFIRLVSVVLAAVFPSICPLLLIFRDPKDPCSVLFKC", "length": 307 }, "evidence": [ { "id": "G3MZM9", "url": "https://omabrowser.org/oma/group/G3MZM9/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "E9Q366-1", "protein_name": "Spermatogenesis associated glutamate (E)-rich protein 4f2", "gene_name": "Speer4f2", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MTMCVRLRRLFQRANVDGRETREGSMDAGLPCERNEGRRRWTWRMWMAHRQTSSPVPVTSNQFEKEEEELMEEIQLISQEKNGLRDYLNLTLGSKITRLNQSYEELKLKQKELMTLQHDLEMATMEAREENEELKKEINFYSNLHSRALMENNLIKKKLMTLQQESKEVQAEWASIQQHLDVNLSGKDEQENNSILDTQEHQVSETARELGLATDQEDSILQDELPPQEAPAEELSPQEAPAEELPPQEAPAEQLPPQEGPAEELPPQESPAEHHLQHPQSFSDESSYITYPEWE", "length": 295 }, "evidence": [ { "id": "G3MZM9", "url": "https://omabrowser.org/oma/group/G3MZM9/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "E9Q3G0-1", "protein_name": "Zinc finger and SCAN domain containing 4B", "gene_name": "Zscan4b", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MASQQAPAKDLQTNNLEFTPTDSSGVQWAEDISNSPSAQLNFSPSNNGCWATQELQSLWKMFNSWLQPEKQTKEQMISQLVLEQFLLTGHCKDKYALTEKWKASGSDMRRFMESLTDECLKPPVMVHVSMQGQEALFSENMPLKEVIKLLKQQQSATRPIPDNAQMPVDTTQDRLLATGQENSENECNTSCNATEVNVGESCSGNEKDSLLITQKEQNHEHEEGNVVCQFPRGARRASQDTSSHHVDFPSALTPADVPMEEQPMDLSRENISEDKNNCYNTSRNAATQVYSGDNIPRNKTDSLFINKRIYHPEPEVGDIPYGVPQDSTRASQGTSTCLQESLGECFSEKDPREVPGLQSRQEQPISDPVLGKNHEANLPCESHQKRFHRDAKLYKCEECSRMFKHARSLSSHQRTHLNKKSELLCITCQKIFKRVSDLRTHEIIHMSEKPFKCSTCEKSFSHKTNLKYHEMIHTGEMPYVCSLCSRRFRQSSTYHRHLRNYHRSD", "length": 505 }, "evidence": [ { "id": "G3MZM9", "url": "https://omabrowser.org/oma/group/G3MZM9/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "E9Q4E0-1", "protein_name": "RIKEN cDNA 5031410I06 gene", "gene_name": "5031410I06Rik", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MALFARLCRLFQRVNVDGRETREGRKDADLPSERNEGRRRWTWRMCMAHRQTTSPVPVKSKKQFEKEEKELIKKIQLTTEETNELRDRLIYVTEGSMNKRPYHRQTRHYKELKLKEKEIMTFLHDLEMKNMEARENNQELKKEKNFYRNLHTRILLGENLIKKKLAILQQESKEIHADWAIIQQRLVELNLSGKDEQEKTSNLEAQENQVSEAARELGLATAEEDSILQNELPCQEAPAEHHPQHPSSSSDESSSDESSYSTCPEWE", "length": 267 }, "evidence": [ { "id": "G3MZM9", "url": "https://omabrowser.org/oma/group/G3MZM9/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "E9Q501-1", "protein_name": "Predicted gene 2237", "gene_name": "Gm2237", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MFSWLLRLFQKENVDEGETRPTEKEEGILSHEKGRRKWFWRRHRSARNTSTQNSKMTKKRSKINELEELKLDMRKISNDMEEMCGILNLYMYEDLNYRMNTEFNIIKSQHEKTMLDMNKMIQSIIGSMQYSKELIEDNYSYSIKEDHLLRECTQLHENVRILLNENRRLLVEQAGHKCPVGKKRGSLRRPARTSVSQVPRNSSPAESRTWH", "length": 211 }, "evidence": [ { "id": "G3MZM9", "url": "https://omabrowser.org/oma/group/G3MZM9/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "E9Q5G7-1", "protein_name": "Oogenesin-1", "gene_name": "Oog1", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MVICLHCPDQDDSLEEVTEECYSPPTLQNLAIQSLLRDEALAISALTDLPQSLFPVIFEEAFTDGYIGILKAMIPVWPFPYLSLGKQINNCNLETLKAMLEGLDILLAQKVQTSRCKLRVINWREDDLKIWAGSHEGEGLPDFRTEKQPIENSAGCEVKKELKVTTEVLRMKGRLDESTTYLLQWAQQRKDSIHLFCRKLLIEGLTKASVIEIFKTVHADCIQELILRCICIEELAFLNPYLKLMKSLFTLTLDHIIGTFSLGDSEKLDEETIFSLISQLPTLHCLQKLYVNDVPFIKGNLKEYLRCLKKPLETLCISNCDLSQSDLDCLPYCLNICELKHLHISDIYLCDLLLEPLGFLLERVGDTLKTLELDSCCIVDFQFSALLPALSQCSHLREVTFYDNDVSLPFLKQLLHHTALLSQLIYECYPAPLECYDDSGVILTHRLESFCPELLDILRAKRQLHSVSFQTTKCSKCGGCYIYDRHTQCCRFVELL", "length": 496 }, "evidence": [ { "id": "G3MZM9", "url": "https://omabrowser.org/oma/group/G3MZM9/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "E9Q6D7-1", "protein_name": "RIKEN cDNA 1700024B05 gene", "gene_name": "1700024B05Rik", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MESHDNPVSAGRTSSQNCNITNHMKNMNKLDDMKFYIRKINAELEELFRILDIDMNTDLNYRMNTEFTIIKSQHEKTMLDMEKMKQSISDSIDKYKEFIEDNDSYSIRHTHLLKECNQLKEKVRMLLNENRKLLVEQADQEASFGEEKSSVMRPARTYIPSAKQQQL", "length": 167 }, "evidence": [ { "id": "G3MZM9", "url": "https://omabrowser.org/oma/group/G3MZM9/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "E9Q7M8-1", "protein_name": "Predicted gene 5796", "gene_name": "Gm5796", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MFSWLLRLFQKENGDEGETRPKKKEEGILSHEKGRRKSFWRRHRSARNTSTQNSKMTKKRSKRNELEELKLDMRKISNDMEEMCGILNLYMYEDLNYRMNTEFNIIKSQHEKTMLDMNKMIQSIIGSMQYSKELIEDNYSYSIKEDHLLRECTQLNENVRILLNENRRLLVEQSGHKCPVGKKRGSLRRPARTSVSQVPRNSSVI", "length": 205 }, "evidence": [ { "id": "G3MZM9", "url": "https://omabrowser.org/oma/group/G3MZM9/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "E9Q8A4-1", "protein_name": "F-box and WD-40 domain protein 28", "gene_name": "Fbxw28", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MEIHLPSVPMMEILSYLDAYSLLQAAQVNKNWNELASSDVLWRKLCQKRWLYCYMFTLPLHGLETWKQFFFDKTWQEHAKTRAKPEDFTYKEFPVEFEFRAHPWYISRHGLTRNGQEKSAVCMTSMNRISTWDIHEGAMTWESPKQPSYIVWMTTLPEMQIAVTIDMQSTIKLWDCHNKEVLASKTGLFFGCKLLQSEFTKDGPIVLVGDACGNLYIFRIPDLHLISKVNVFPYSIDELYFSPQKKWVFLIGHRLNDLTKVFYMSSLLRPSEFSAPVSTVLKVPVIRKVFWTPRREDRITLMSLILPKNITKFDTFDMKLEGIGNKVTIQGYLTASFSLAEDEGRPDYFGVSDKDVIVCSTRFSLLLFDINGLRLQTFHYCPEEIWRLWVDPVHVIVTCDAGSLDIYAWEKRSLLLRKCYRLRNRNYQQMSGYIIKTLCDDMSIISVANNSPKPCCLMAYTLSVCS", "length": 466 }, "evidence": [ { "id": "G3MZM9", "url": "https://omabrowser.org/oma/group/G3MZM9/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "E9Q8I6-1", "protein_name": "Vomeronasal type-1 receptor", "gene_name": "Vmn1r55", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MEMLALQILLLCQVVVGTVGNILLFVHNFSPILTDSRLRPIQVILINLAVANAFMLLLLTYSHDMIDLVPKNPPTDLKCKLAHFFHMVARGTNMCSTCVLSTYQFVTLVPGNWARVMFREISPKVVRYSCYSCWLFSVLNNAYIPMNVRGPKKSHNDSDSQGKRMCSISVVNVDMNYLQFSYDIIFIGIMVWTSVSMVIHLNRHHQRMHYIHNPNQSNRGHAETRAAHTILMLVVTFVSLYILNCICVLFHVSFVESRRWLRNVIEFLALSFPTISPLLLIFRDPRGPCSLYFNVGLEIHVTGKVITEEQ", "length": 310 }, "evidence": [ { "id": "G3MZM9", "url": "https://omabrowser.org/oma/group/G3MZM9/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "E9Q8L6-1", "protein_name": "Vomeronasal type-1 receptor", "gene_name": "Vmn1r132", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MSAHGKSVKTTEEVALQILLLCQFGVGTVANVFLFVHNFSPVLTGSKQRPRQVILSHMAVANALTLFLTIFPNNMMAFAPKTPPTELKCKLEFFSHMVARSTNLCSTCVLSVHQFVTLVPVNRGKGKLILRASVPNLWNYSCYSCWFFSVLSNIHIPIKVTGPQIIDNNTYDKSNLFCSTSGFIVGIVFLQISHDATFMSIMVWTSVSMVLLLLTPNQDARGQAETRATHTILMLVVTFVSFYLLNCICIIFHAFSIHSRLFIRLVSEVLAAVFPSICPLLLIFRDPNDPCSVLFKC", "length": 297 }, "evidence": [ { "id": "G3MZM9", "url": "https://omabrowser.org/oma/group/G3MZM9/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "E9Q8T0-1", "protein_name": "Vomeronasal type-1 receptor", "gene_name": "Vmn1r7", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MSSFKNVLYFQTGLGVLANTVLLFFYVFIILGHRPKPTDLISCQLSFVHIMVVLIGGDILLADIFESLNIGNDFKCKTTFYLFRVMRGLSICITCLLSVFQAVTISPNTSVLAKFKQKVKKYMTHVFLCIWFFNLSFSTNQIFYVGGFTNVSETNQMQVTKSCSLLPMNYIIRGLIFTISISRDVFLVGVMLTTSVYMVIFLFRHQRQCKHLHSFSHPRESPEKRATQTIMLLVSFFVVLYWMDFIISFTSEMLRMYDPVILTLQKFMMYAYPTITPLVQISSDNRIIIMLKNIQSKCHPSFSLKDFFFFI", "length": 311 }, "evidence": [ { "id": "G3MZM9", "url": "https://omabrowser.org/oma/group/G3MZM9/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "E9Q8V7-1", "protein_name": "Vomeronasal type-1 receptor", "gene_name": "Vmn1r173", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MSALNKALKTTEEVALQIILLCQVGIAAVANILLLVHNLSPNFAGPQLRPKHVILAHITVGNLLIILLTGFPSNIIVFVPRNPLNDLNCKLEYFIRLVARSANMCTTCVLSTYQFIVLVPGKWSRMILRGNTSTFVHYSCNSCWIISVLNNVYIPIKISGPWNTDNDTDLNSKWVCSMSGFELVMVFLRFVHDTMFISIMVWTSVSMMLLLYRHHQSLKHIHRSNGSLGLQPEARAAYTILMLVVTFVCFYLLDCMCIFFHISFVHFRVWLRHVNEILAASFPTLSPLMLIFRGPKKISAKGINTENAFINSH", "length": 313 }, "evidence": [ { "id": "G3MZM9", "url": "https://omabrowser.org/oma/group/G3MZM9/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "E9Q9N3-1", "protein_name": "Vomeronasal type-1 receptor", "gene_name": "Vmn1r152", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MSAHGKSVKTTEEVALQILLLCQFGVGTVANVFLFVHNFSPVLTGSKQRPRQVILSHMAVANALTLFLTIFPNNMSAFASKTPPNELKCKLEFFSHMVARSKNLCSTCVLSIHQFVTLVPVNRGKGKLILRASVPNLWNYSCYSCWFYSVLSNIHIPIKVTGPQITDNNTDSKSNLFGSTSGFIVGMVFLQFSHDATFMTIMVWTSVSMVLLLHRHRQQMQHILTPNQDARGQAETRATHTILMLVVTFVRFYLLNCICIIFHAFSIHSRLFIRLVSEVLAAVFPSICPLLLIFRDPKDPCSVLFKC", "length": 307 }, "evidence": [ { "id": "G3MZM9", "url": "https://omabrowser.org/oma/group/G3MZM9/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "E9QAN3-1", "protein_name": "Predicted gene 1979", "gene_name": "Gm1979", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MALFARLCRLFQRANVDGRETREGRKDADLPPESNEGRRRWTWRMWMAHRQKTSPVPVTSKKQFEKEEKELIKKIQLTTEETNELRDRLIYVTEGSMNKRPYHRQTRHYKELKLKEKEIMTYLHELEMKNMEARENKQELKKEKNFYRNLHTRILLEENLIKKKLAILQQESKEIHADWAIIQQRLVELNLSGKDEQEKTSNLETQEHQVSEAARELGLATAEEDSILQNELPCQEAPAEHHPQHPPSSSDESSSDESSYSTCPEWE", "length": 267 }, "evidence": [ { "id": "G3MZM9", "url": "https://omabrowser.org/oma/group/G3MZM9/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "E9QD93-1", "protein_name": "Granzyme K", "gene_name": "gzma", "tax_id": 7955, "organism": "Danio rerio", "sequence": { "sequence": "MDICRNLIVFHFLVFTFFKVTVCSDVSIVGGKDVKKALSWMVSIQVNQNHKCGGILIHKEWVLTAAHCKEDSYSSVTVLIGSLSLSKGSQRIAIHNYEIPETFNKKTKKDDIMLIRLSKKVKAKPYKIPKKEKDVQPGTKCVVRGWGTTDYKGKQASDKLQMLEVLVVDRVQCNRYYNRNPVITKDMLCAGNTQQHRGTCLGDSGGPLECEKNLVGVLSGSHGCGDPKKPTVYTLLSKRHITWINKILKQQFNSTRF", "length": 257 }, "evidence": [ { "id": "G3MZM9", "url": "https://omabrowser.org/oma/group/G3MZM9/", "database": "OMA" } ], "glygen_name": "Zebrafish", "common_name": "Zebrafish" }, { "uniprot_canonical_ac": "E9QLQ1-1", "protein_name": "Defensin, alpha, 35", "gene_name": "Defa35", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MKTFVLLSALVLLAFQVQADPIHKTDEETNTEEQPGEEDQAVSISFGGQEGSALHDELSKKLICYCRIRGCKRRERVFGTCRNLFLTFVFCCS", "length": 93 }, "evidence": [ { "id": "G3MZM9", "url": "https://omabrowser.org/oma/group/G3MZM9/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "F1LPT0-1", "protein_name": "Gap junction protein", "gene_name": "Gjc3", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MCCSFLRQLLARESQHSTPVGRFLLPVLVGFRLLILVSSGPGVFGNDENEFMCHLGQPGCKTICYDVFRPLSPLRFWAFQVILMAVPSAIYVAFTLYHVIGYWEVPGRNKEQEAQICKGGRCKDVSGAMSLKLLWAYVAHLGVRLVLEGAALGVQYHLYGFKMPSTFICREDPCIGSTTCFQSHPSEKTILLNTMFGISGACLLFIFLELVLLGLGRVWKTYRHKLPLFKNLSTSERSVRHKDTTDDLSVVETKEPF", "length": 257 }, "evidence": [ { "id": "G3MZM9", "url": "https://omabrowser.org/oma/group/G3MZM9/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "F1LT33-1", "protein_name": "Cytochrome P450", "gene_name": "Cyp2b14", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MELGVFLLLTFTVGFLLLLASQNRPKTHGHLPPGPRPLPFLGNLLQMNRRGLLRSFMQLQEKYGDVFTVHLGPRPVVILCGTDTIREALVDQAEAFSGRGTVAVLHPVVQGYGVIFANGERWKILRRFSLVTMRNFGMGKRSVEERIKEEAQCLVEELKKYKGALLNPTSIFQSIAANIICSIVFGERFDYKDHQFLRLLDLIYQTFSLMGSLSSQVFELFSGFLKYFPGVHKQISKNLQEILNYIDHSVEKHRATLDPNTPRDFIDTYLLHMEKEKSNHHTEFHHQNLVISVLSLFFAGTETTSTTLRYSFLIMLKYPHVAEKVQKEIDQVISSHRLPTLDDRIKMPYTDAVIHEIQRFADLAPIGLPHRVTKDTMFRGYLLPKNTEVYPILSSALHDPRYFDHPDTFNPEHFLDANGTLKKSEAFLPFSTGKRTCLGEGIARNELFIFFTALLQNFSLASPVAPEDIDLTPINSGAGKIPSPYQINFLSRCVG", "length": 495 }, "evidence": [ { "id": "G3MZM9", "url": "https://omabrowser.org/oma/group/G3MZM9/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "F1LYQ4-1", "protein_name": "Alpha-1-B glycoprotein like 1", "gene_name": "A1bgl1", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MDLLVLLEPLASLTLTCKVCEPSKDLHRILHLSSMETACTLSLALPPTLPSASLIFSASGVHTLILLRVRLNHSLILLSLIHTGPLPRPWLSANPVPWITPGLRTFLLCQGTVRDVVFMLRREGDDGNKEKEQGIFQVHEPGNYSCNYYTNTEYTPSKPSGTVTIKEYVIPPPPMLTSLESSTVDEPEMTQMSLLCVAPLSDVEFQLRQGEREMKVLIVSTSPERASFYLKLSDMGDHSPFTCRYRLNRMTAWSEDSKPVQLMWSDETLPEPVLTVEPSPHQSFEPGSTVQFRCTAPKAGLRSEAGLRFGLHLEDLYDHRLLQTQKSSGNETVFQLRNVSATDSASYSCIYTELTPPYSGSAPSDFVILRVNGPPPPPKLQALWTGKVFAGHDVVLRCQSDVTGVIVELLRDGKFVPYRILRVLNNYSDLGLHSVGPQHTGNYTCRYTSWLPEPVQSEPSNPVELLVEGMASGVVVVGFCLLIFPGLCILVNCAI", "length": 495 }, "evidence": [ { "id": "G3MZM9", "url": "https://omabrowser.org/oma/group/G3MZM9/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "F1M6N1-1", "protein_name": "Zinc finger protein 945 like 1", "gene_name": "Zfp945l1", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MTASLVNVSKCLLTFRDVAVEFSMEEWECLNYSQKTLYRDVMMENYNNLLFVENHCKYKKVLDQDPNSIVHNVNIYEKAYECNELVKMTHESSQGTPFKTKHKDASLQISTLNRQKIGNTRDEPCKFKDCINFLNVFVIRQNQRIYIGEKEPTTIEYENHYNSKHEVMLKQSNSTGNKPHIFRKYGQCFKIYSSFSRYQNDHTSEKFYKCIKCRKSFLHLSQLKVHYKIHYRKYPCKCTACSKCFYHTFGFKRHYSIHPEVNTYKSSDCDKSFIYYSSLRKHQKIFGGERHYECNEGLRSLYTVFQPVYYYIPHIGEKAYKCSECEKCFTRKYHLTVHQRIHTGEKPYKCGECDKCFTRKYHLTDHQRIHTGEKPYKCSECKKCFTRKYHLTDHQRIHTVEKPYKCSECGMSFMKKYHLRSHQSIHTGEKPYNCSECDKGFTYKGHLRRHQKIHTGEKPYKCSECAKCFTENSKLRRHQRIHTGENLYKCSECDRCFIENNKLRSHQKVHIGEKPYKYSEYDKCLTQKGSLRSHQLIHTGEKPY", "length": 544 }, "evidence": [ { "id": "G3MZM9", "url": "https://omabrowser.org/oma/group/G3MZM9/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "F1M7A9-1", "protein_name": "Large ribosomal subunit protein uL6", "gene_name": "AABR07026048.1", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MANRLAHRPIQWRNFLSQDSLDQDTMRKKTILSNQTVDIPENVDITLKGRTAIVEGPRGTLRRDFNHINVELSLLGKKEKRLRVDKWWGNGKELATVRTICSHVQNVIKGVTLGFCYKMRSVYAHFPINVVIQENGSLVEIRNFLGEKYIRRVWMRTNVACSVSQAQKDELILEGNDIELVSNSAALIQQGTTVKNKDISKFLDGIYVSEKGTVQQADE", "length": 219 }, "evidence": [ { "id": "G3MZM9", "url": "https://omabrowser.org/oma/group/G3MZM9/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "F1M9J5-1", "protein_name": "Uncharacterized protein", "gene_name": "Esp1", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "ITFLPVTLFLIILLWPSMITEGRVLTQNQKELSISADHNKNHKSDLDKIEFQGQPNIQKAVEMTICASDKDQTLLEDQANANQDKQLYKDSHLLCGRSLDHIVK", "length": 104 }, "evidence": [ { "id": "G3MZM9", "url": "https://omabrowser.org/oma/group/G3MZM9/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "F1QDL3-1", "protein_name": "Novel nacht domain containing protein", "gene_name": "LOC560232", "tax_id": 7955, "organism": "Danio rerio", "sequence": { "sequence": "MEDKHTPGDLDLSTGCSSVHQNRAEAEPSCVSMKSDVSMDPPTNFKSGNTGPAVSSRKRKRAEAEPSCVSMKSDASMDPPLKFKSKNTQPAVSVDRDDQSGDLLQDSLQPEHDELQRVKEQHKTTMKNKHERLFEGINHGETQTLLNRIYTQLYIIEGESEGVNEEHEVIQMEKRARTKPSQHTPVYCNDIFKASAGAGHEVKIKKEKAQIKTVLTKGIAGIGKTVSVQKFILDWAEGKANQDVDFMFVLPFRELNLIRDHQYSLHRLLLDFHPELEDLEPKIYEQCRVVFIFDGLDESRITLNFSDEEKVCAVTESSSVAVLMWSLLKGDLLPSALIWITSRPAAAHQIPSRYIKRLTEIQGFTEPQKEEYFRKRISDEHQASRIISHIRRARSLQIMCHIPVFCWISSTVLQKLLEEDVSAEIPQTLTEMYIHFLLIQINMRKQKYEERDPEKLLQSNRGVILKLAEVAFRQLMKGNVMFYEEDLIESGIDVTDALVYSGICTEIFKEESVIQQRKVYSFIHLSFQEFLAAFFVFYCHLTKKRELLELILGYSYDQYLQSSSEKSLYDLLSSAVDEAVRSSNGHLDLFLRFLLGVSLESNQRLFQDLLTHTEESSESIRRITQYIKDQIKSDDYFKRAAERFINLFLCLLEVKDQTLAREIQEFVKSDKHSEEELSPAHCSTISYMIEMSEEPLDEFELQKFNTSAEGRLRLTTAVRNCRRAL", "length": 725 }, "evidence": [ { "id": "G3MZM9", "url": "https://omabrowser.org/oma/group/G3MZM9/", "database": "OMA" } ], "glygen_name": "Zebrafish", "common_name": "Zebrafish" }, { "uniprot_canonical_ac": "F1QGM0-1", "protein_name": "Galectin", "gene_name": "lgals1l1", "tax_id": 7955, "organism": "Danio rerio", "sequence": { "sequence": "MPTVLIQNMAFKVGQTLTLTGVPKPESPEFTIDIGNSSEDIALHINPRFDAHGDQCIIVCNTFQNDCWCEEHRDENFPFVQGEEFQIKITFTNEEFLVTLPDGSEINFPNRQGSEKYKYMNFTGQARIQGIEIK", "length": 134 }, "evidence": [ { "id": "G3MZM9", "url": "https://omabrowser.org/oma/group/G3MZM9/", "database": "OMA" } ], "glygen_name": "Zebrafish", "common_name": "Zebrafish" }, { "uniprot_canonical_ac": "F1QMQ9-1", "protein_name": "Uncharacterized protein LOC541480", "gene_name": "si:ch1073-398c20.1", "tax_id": 7955, "organism": "Danio rerio", "sequence": { "sequence": "MADIKQESDDIRIAEVFTLKQEDPEEQTDLLPLRKEFQGLDNVKEEEALVEEHQDITPAEKRITCSETENTTQKASEKTGSRSSFTCEQCGRDFAKQGTLNNHMRIHTGEKSFTCQQCGKGFTQKRTLRNHIRFHIEAESLSCQQCGESFTQKQDLTDHMRVHTGEKSFVCDQCGKVFLRKDGLEKHLKNHHKEKPHVCPCGKSFTDKTKLEEHTKTHTGEKPHTCDKCDECFSGKYDLIRHMRFHSAETPYICQQCGKSFALKRVLMTHVKIHTRDRPFLCKQCGKCFYRKDNFNRHVRVHTGEKPYACSECGKSFSERFQFNEHSRTHSGVKRFSCEQCGRGFNRKTELKRHMRVHTGEKPYMCPQCGKTYAFKTGFDIHMLHHNAEMPYICPQCGERFSVKQRFDVHMKIHAGNSDK", "length": 420 }, "evidence": [ { "id": "G3MZM9", "url": "https://omabrowser.org/oma/group/G3MZM9/", "database": "OMA" } ], "glygen_name": "Zebrafish", "common_name": "Zebrafish" }, { "uniprot_canonical_ac": "F1R1Q6-1", "protein_name": "Uncharacterized protein LOC641576", "gene_name": "zgc:152710", "tax_id": 7955, "organism": "Danio rerio", "sequence": { "sequence": "MVLIWTQFGVKHKNVKCKVRVIHGEEGSWSSEEVREEPEVSSPPPSPECVDYYSVLGVSNDSNEEEIRKAYKRLALRYHPDKNSDADAEDKFKQIAQAYDVLTDPEKRNIYDQQGLTKGGVAPTCNKTDPSHNSKADAHSWHMFFNFDLDSDDDLFNPFTRNPLPHLSRHHGNKGGLKPAGDAEVHDLSVSLEDILMGVTKRVKLTRLRQTDKHTLKPEERVFDVEVKKGWKEGTRITFPNEGHQMLGHAPNDLAFVIKEKKHAHFRRDGSHIVYTCTITLREALCGCTVNVPTLDGQMKPLPCSDVIKPSSVRRLIGEGLPRAKNPAQRGDLLVEFQVVFPDRIPPSSKEIIKHSLGQC", "length": 360 }, "evidence": [ { "id": "G3MZM9", "url": "https://omabrowser.org/oma/group/G3MZM9/", "database": "OMA" } ], "glygen_name": "Zebrafish", "common_name": "Zebrafish" }, { "uniprot_canonical_ac": "F1RA39-5", "protein_name": "[F-actin]-monooxygenase mical2b", "gene_name": "mical2b", "tax_id": 7955, "organism": "Danio rerio", "sequence": { "sequence": "MGETEEERTSQAGQLFENFIQATTCKGTLQAFSVLCRQLELNPSDHRGFYSSLKTAVTFWKAKGLWGKLDKRAGHKEYSKGRACADTRCLIIGGGPCGFRTAIELALLGAKVVVIEKRDTFSRNNVLHLWPYTIHDLRNLGAKKFYGKFCAGSIDHISIRQLQLMLLKIALIVGVEVHVNVEFVKLLEPPEDQSTDGQGWRAEIRPADNPVSDYEFDVIIGADGRRSTLDGFRRKEFRGKLAIAITANFVNRNTTAEAKVEEISGVAFIFNQKFFLELKEETGIDLENIVYYKDNTHYFVMTAKKQSLLDKGVIINDYIETERLLAFDNVNQEALLSYAREAADFGTNYQLPSLDYAINHYGQPDVAMFDFTCMYASENAALVREKSHRQLLVALVGDSLLEPFWPMGTGCARGFLAAFDTAWMIKGWAQGKEPLDLLSERESIYRLLPQTTAENISKNFEQYTIDPATRYPNLNSSCVRPHQVRHLFISGEQDLSSLERSGQTRRSVSISRRESEVRPGRLLLWCQNQTQDYRGVNVTDLNTSWRSGLALCALIHRQRPELIDFDSLNEADCAKNNQLAFDVAEREFGIQPVTTGKEMDAERGPDKLIMVLYLSKFYEMFHKSTQSVTGLPKEIDANNGDCSSKTANSLYNSINHARKRIPKLDKKLEESDVNRKRKKASSHHEELMSCQTAPPAGEREEQKENKVRSMATQLLARFEENAPSCALRRQSDSESDSDADRPVSLDLTENPRFARPKIEPTHPSTTPDKAKWQPSPYLRLLESNTRSETLHTEHYVESQSSHRLTEIQSECQYSSVSSAYKSSERRPRSPLIPFTPTLSPMMHCLQQLEEQVIQQRKREPLNRKSIKERAQKLSSLFTGNPAQPQTDESSPAVSPSSPPQTIPESSTLSCLLSPAPSLTHKQCSEASETHLKADKHTEIRRVERLDPSKQRTVGKVSSAIGVKAATLAILYETDHRPNNPITLSLTEARRCAESGLVSVRKEFSASLGGSDTCVFCQKRVYIMERLSAEGFFFHRECFRCHICGCSLRLGAHTFDSQQGTFYCKMHFSQRKTSTRHRRGEIQDGGIRSSSITISNHTSTDGTRGQPSGGEFDSSTQQDLQTLPDSKEIISVSEVKDSSKKADPADSAPACPDSPLQKVKRSTAKGEITNKNILWKKKIRSTLPLVLMKKFHRGKPEDKTEVLAEEDGNSDFEEIHESLSSKKPSNPSTDSNCLPTKDNSSTPLDEIPKIPLYRTHVLPEYPKPSSSSPEPIVTSISSDPISFSPKKKLTLSLSEKEKLLNWDLTNPGKSGAEEQQQQHVKPSISLQHDHPEPTHPQPEPAPPLFGFQQWANNLRKSFSKGSNPVVLRRNRPMKARPLSEGSFNVGAVFQDEERCGSLVDEGEARPRTESEIASLLEQVALGSKTSRGTKDDMASLPPRKLNFFSSLRIKRVEGAEQSRGEGQKDILSILSRFRNKASAQQQQQQKSNSSSEDEQEPKLTHSGALQKKKEKIAIRQTKSDELKRLHRAQVIQRQLEEVEEKQRSLEEKGVALEKVLRGENGDDGSTDEAALLQTWFKLVLEKNKLSRYESELMIFAQELELEDTQSRLQQDLRRRMATEDCEKSASELVEEQNILVEIMKVVEKRDKLVSLLEEQRLKEKAEDRDLESLILSRGYQFHWT", "length": 1679 }, "evidence": [ { "id": "G3MZM9", "url": "https://omabrowser.org/oma/group/G3MZM9/", "database": "OMA" } ], "glygen_name": "Zebrafish", "common_name": "Zebrafish" }, { "uniprot_canonical_ac": "F1RXL1-1", "protein_name": "Olfactory receptor", "gene_name": "LOC100152495", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MFTICNDSHSDFILLGFSDKPYLEKILFWVVLIFYCLTIIGNLVIILVSLKDPKLHIPMYYFLSNLSLLDLCFTSSCVPQMLVNFGGPEKTISYIGCAIQLYVFLWLGATECVLLVVMAVDRYVAVCHPLQYTTIMHPKLCLELAILAWGTGLIQSLTQSPATLQLPFCSNRRLYDIVCEVPALIQVSSADTIYNEIQMSIASIILLVVPLVIILSSYGAITKALLRVKSTEGQKKAFGTCTSHLLVVFLFYGTVTAVYLQPKSHYAHEQGKFLTLFYTVITPTLNPLIYTLRNKEVKGALIRLGKKTWDDLCWTIA", "length": 317 }, "evidence": [ { "id": "G3MZM9", "url": "https://omabrowser.org/oma/group/G3MZM9/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "F1RYD0-1", "protein_name": "Transcription elongation factor A like 3", "gene_name": "", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MRQVKHLRSGSLPTPGLSVTSPSPTARPATPRTACLFPALCKTRKGEGTCPESLQDKKRRKNLNMEKLCKENEGKPESEGKPEDEVEPDNEGKSDEEEKPEVEGKSAHEGKLQNEGQPEDEGKPEDEGKQEKQGKSEDEGKPPGEGTMESQAKPESEPRAAEKRPAEDYVPRKAKRKTDRVTDDSPKDYEEDLQERHLGSEEMMREGGDLSRAQEELRKRQKMGGFHWMQRDVQDPFTPRGPRGVRGMRGGGRSQRGLHDIPYL", "length": 264 }, "evidence": [ { "id": "G3MZM9", "url": "https://omabrowser.org/oma/group/G3MZM9/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "F1RYD7-1", "protein_name": "Olfactory receptor", "gene_name": "LOC110258723", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "LLVVVLVTYLLTLVGNTVIILIASIDPNLKTPMYFFLTHLSLVDICLTTSIVPQLLWNLRGPAKTITTLGCAVQLYVSLALGSTECVLLAVMAFDRHAAICKPLHYAAVMNPRLCQALAGVAWLSGVGNALIQSTVTLWLPRCGHRRLHHFFCEVPSMIKLACVDIHTNEVQLFIASLVLLLLPLALILTSYGHIVKAVTRIKSVQAWRKALGTCGSHVMVVSLFYGTITAVYIQPNSSYAHTSGKFISLIYTVLTPTLNPLIYTLRNKDVKGAMRRLFRRDLGS", "length": 285 }, "evidence": [ { "id": "G3MZM9", "url": "https://omabrowser.org/oma/group/G3MZM9/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "F1S4M2-1", "protein_name": "Small ribosomal subunit protein uS13", "gene_name": "", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MSLVILEKFQHILRVLNTTIDGWQKIAFATTAIKGVGRRYAHVVLRKADIDLTKRAGELTEDEVEHVITIMQNPGQYKIPDWFLNRQKDVKDGKYSQVLANGLDNKLHEDVERLKKIRAHRGLRHFWGLRVGGQHTKTTGRRGHTVGVSKKK", "length": 152 }, "evidence": [ { "id": "G3MZM9", "url": "https://omabrowser.org/oma/group/G3MZM9/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "F1S6C0-1", "protein_name": "RING-type domain-containing protein", "gene_name": "", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MGNCLTPHTSEDLLVPASATHLGGRRRRARSRERRPRDQVPGWAPAAPLVQEEQVRVPQRISQIQCLPKGVYKRDGSQEKMEQEECAICTLDFVCGDPIRSLPCKHFYHLGCIDEWLTRSFTCPYCRGPADGPQPSSRDTP", "length": 141 }, "evidence": [ { "id": "G3MZM9", "url": "https://omabrowser.org/oma/group/G3MZM9/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "F1S7I2-1", "protein_name": "Beta-defensin", "gene_name": "DEFB125", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MNLLLTFMICGLLTLVTKAGWNVERCWSYNIGHCRRRCLHLERYKHLCMNKRACCIPLSSDDPYTQWPLPPEDQTVGMKTPYFRPVSPGSELDDQITITITVDQESTGTEQDIEGTAISFQASTPIPENIEDTKFSDKANTLNLHKL", "length": 147 }, "evidence": [ { "id": "G3MZM9", "url": "https://omabrowser.org/oma/group/G3MZM9/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "F1S7N4-1", "protein_name": "Olfactory receptor", "gene_name": "LOC100152708", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MDQTNSSVVTEFVLVGLTQSLGMQFLLFLLFSTFYVGIILGNLFIVFTVISDSHLHSPMYILLANLSLIDLGLSSTTVPRMISDLFSDCKTISFHNCMIQMFFIHVTGGVEMVLLIAIAYDRYTAICKPLHYLTIMNPQMCMLLVVAAWITGVTHAVFQFAFVINLPFCGPNNVGSFYCDFPRVIKLACIDNYGLEFVVTANSGFLSTGTFFLLVVSYIFILVTVRQHSSKDLSKAFFTLSTHITVVFLFFLPCMFLYVWPFPTKSLDTFLAIVDFAVTPVLNPAIYTLRNRDMKVEMRRLSRQVISSREMT", "length": 312 }, "evidence": [ { "id": "G3MZM9", "url": "https://omabrowser.org/oma/group/G3MZM9/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "F1SBB9-1", "protein_name": "DNA-directed RNA polymerase RBP11-like dimerisation domain-containing protein", "gene_name": "", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MHALPAFESFLLFKDEKITIHKDTKAPNACLFTIDKEDHTLGNVIKSQLLKDPQVLFAGCQVPHPWEHKIIVPVQTTPDYTPQEALLNVITDLISKLSLLEERLRVAIKDKQEGIECWTGRGPAWPGPALTLALLQAPCG", "length": 140 }, "evidence": [ { "id": "G3MZM9", "url": "https://omabrowser.org/oma/group/G3MZM9/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "F1SBV4-1", "protein_name": "Olfactory receptor", "gene_name": "LOC100154723", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MESENITVVTEFIFVGLTQSRNIQLLVFVLVFIFYLIILPGNFLIILTIRSDPGLTAPLYFFLGNLAFLDASYSFIVAPRMLVDFLSEKKVISYRGCITQLFFLHFLGGGEMLLLVVMALDRYIAICRPLHYSTVMNPRACYALSLAQWLGGFVHSIIQVALILHLPFCGPNRLDNFFCDVPQVIKLACTDTFVVELLMVFNSGLLTLICFLGLLASYAVILCRVRGSSSEGKTKAMSTCTTHIIVIFLMFGPGIFIYTRPFRAFPADKVVSLFHTVIFPLLNPVIYTLRNQEVKTSLKKLLINN", "length": 305 }, "evidence": [ { "id": "G3MZM9", "url": "https://omabrowser.org/oma/group/G3MZM9/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "F1SJ79-1", "protein_name": "Olfactory receptor", "gene_name": "LOC110259717", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MEQNNGTKGTEFILLGFAGQHKSWPVLFIVFLVTYVVTLVGNIGMILLIKIEASLHTPMYFFLQNLEEKVDLCYATAITPKMLQNFVWTEHSISFIGCMVQLLTYGAFATSDCYILAAMAVDRYVAICNPLRYPTVMSQRVCIQLVIGSYFMGFLNASVNTSFTFQLNFCKSNKINHFFCDAPPILALSCSSIYFSIMLLAAFVGFNLTCTVSVVIFSYVFILAAILKISSAAGRKKAFSTCASHLTAVTLFYGTLSYMYLHHRTLESQEQEKLASVFYGIVIPMFNPLIYSLRNQDVREALKGVGKQCF", "length": 310 }, "evidence": [ { "id": "G3MZM9", "url": "https://omabrowser.org/oma/group/G3MZM9/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "F1SLL7-1", "protein_name": "Olfactory receptor", "gene_name": "", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MRRENQSSISKFLLLGLPIQPEHQGMFFVLFLVMYLTTVLGNLLIILLIRLDPRLHTPMYFFLSHLALTDVSFSSVTVPKMLMNMQTQDQSIPYAGCVTQTYFFIFLACIDNLLLAVMAYDRYVAICHPLHYAIIMREELCLCLLVLSWLLSCAYALTHTLLLAQLSFCADIIPHFFCDLDALLKLSCSDTSLSELVTFTAGAAVVIFPFIGILVSYGHIGLSILRVPSTKGICKALSTCGSHLSVVSLFYRTSMAVYLSSSGQFHDKDIIVSVMYTVVTPMLNPFIYSLRNRDMTLALGILFRNINIFSK", "length": 311 }, "evidence": [ { "id": "G3MZM9", "url": "https://omabrowser.org/oma/group/G3MZM9/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "F1SMZ6-1", "protein_name": "10 kDa heat shock protein, mitochondrial", "gene_name": "HSPE1", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MAGQAFRKFLPLFDRVLVERSAAETVTKGGIMLPEKSQGKVLQATVVAVGSGSKGKGGEIQPVSVKVGDKVLLPEYGGTRVVLDDKDYFLFRDGDILGKYVD", "length": 102 }, "evidence": [ { "id": "G3MZM9", "url": "https://omabrowser.org/oma/group/G3MZM9/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "F1SRB7-1", "protein_name": "Large ribosomal subunit protein eL31", "gene_name": "", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MAVVQKSGEKKRGRSAINEVVTREHTTSIHKRIHGVGSKKRAPRALKEIRKFAMTEMGTPDVRNDTRLNKAVWAKGIRNVPRRICAPLSRKRNEDEDSPNKLYPLVTCVPVTTFKNLQTVNEDEN", "length": 125 }, "evidence": [ { "id": "G3MZM9", "url": "https://omabrowser.org/oma/group/G3MZM9/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "F1SUB9-1", "protein_name": "Multifunctional fusion protein", "gene_name": "IL1B", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MATVPEPAKEVMANNGDNNNDLLFEADGPKEMKCRTQNLDLSPLGDGSIQLQISHQLCNESSRPMVSVIVAKEKPMNPSSQVVCDDDPKSIFSSVFEEEPIVLEKHANGFLCDATPVQSVDCKLQDKDEKALVLAGPHELKALHLLTGDLKREVVFCMSFVQGDDSDDKIPVTLGIKGKNLYLSCVMKDDTPTLQLEDVDPKSYPKRDMEKRFVFYKTEIKNRVEFESALYPNWYISTSQAEQKPVFLGNSKGRQDITDFTMEVLSP", "length": 267 }, "evidence": [ { "id": "G3MZM9", "url": "https://omabrowser.org/oma/group/G3MZM9/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "F2Z5L2-1", "protein_name": "Histone H2A", "gene_name": "H2AC18", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MSGRGKQGGKARAKAKSRSSRAGLQFPVGRVHRLLRKGNYAERVGAGAPVYMAAVLEYLTAEILELAGNAARDNKKTRIIPRHLQLAIRNDEELNKLLGKVTIAQGGVLPNIQAVLLPKKTESHHKAKGK", "length": 130 }, "evidence": [ { "id": "G3MZM9", "url": "https://omabrowser.org/oma/group/G3MZM9/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "F4IWB9-1", "protein_name": "Cytochrome P450, family 705, subfamily A, polypeptide 28", "gene_name": "CYP705A28", "tax_id": 3702, "organism": "Arabidopsis thaliana", "sequence": { "sequence": "MIMGRSCSEKNGEAERVRGLVIESLALSPKIFLGMIFHKPLKKLGISLFQKDIKSVSPKFDELLEKFLVEHEEKMEEDHYKANDMMDLLLEAMEMRMQNVNLCIKRVSNTKARKPPILFRYGKYSNNSLLLQELLVAGTDTSALATQWTMAELINNPTILERLREEIESVVGNTRLIQETDLSNLPYLQSVVKEGLRLHPPASISVRMSQERCELGGFYIPEKTLLVVNTYAIMRDPNFWEDPEEFKPERFITSSRSEQEDEMREEVLKYIPFSAGRRGCPGSNLAYVSLGIAIGVMVQCFDWRIKGEKVNMSETAGTIMLAMAQPLKCTPVPRTLNLLPSSLHIPSS", "length": 348 }, "evidence": [ { "id": "G3MZM9", "url": "https://omabrowser.org/oma/group/G3MZM9/", "database": "OMA" } ], "glygen_name": "Arabidopsis", "common_name": "Mouse-ear cress" }, { "uniprot_canonical_ac": "F4J311-1", "protein_name": "Zinc finger (C2H2 type) family protein", "gene_name": "", "tax_id": 3702, "organism": "Arabidopsis thaliana", "sequence": { "sequence": "MDLDGVELLLDLREMVSQSGFEKSTTCSGVIALRSNLQSKSSHKCKICGKSFECYQALGGHQRIHRPIKEKLSKQEFSEVYPRKSKLQKRPESSSSCYECKVCGKIFGCYRGLGGHTKLHRSTKRELASTQDENSLLDSSEAKKIVSQPSSFKVSQEEKFLHCVELKQDFSEPLSHSGALPSTLRSKLQTKTQWKSSCHCKICGKSFVCSQGLGNHKRVHREISGKLACKRKYTEDYNPFSDSLKAKKIVKKPSSFEVSQEEKILHCVELKQDFGELLAHSGFDKSISCSKSIKVKKVARKNEKTEDSTSLFGVFVGEMSQRLHGCKTCGRKFGTLKGVYGHQRMHSGNHNRIEDENGLERIWGLKKKSRVCSVSAFDRFKGSSFMAEIEKHEVIEAALNLVMLCQGVYDFASISNLPLGDGFMDLELKPCPLRRKLQKKSRSSYKCSICEKSFVCSQALGSHQRLHRWKLVPKPEYIEDDSSLLDSSEAKKIVSKPSSFEHAQEEKILQCVEPKLEFHEQLAHSGFDKFDTCSKIRFSALPSPPEAKKIVSQPPSFEVSVDEKILYRAEPKLNFSEPLAHSCFDNSSSYRSIICGKSFVCSQALGGHQTLHRSIKGQLAGTEDGNSLSVTDSEASKIVAQPSSYKSQGI", "length": 650 }, "evidence": [ { "id": "G3MZM9", "url": "https://omabrowser.org/oma/group/G3MZM9/", "database": "OMA" } ], "glygen_name": "Arabidopsis", "common_name": "Mouse-ear cress" }, { "uniprot_canonical_ac": "F4JLV4-1", "protein_name": "Protease inhibitor/seed storage/lipid transfer protein (LTP) family protein", "gene_name": "DHYPRP1", "tax_id": 3702, "organism": "Arabidopsis thaliana", "sequence": { "sequence": "MASTTIILFLSFSIIPLLTIVRADNHSVYCPPPPPCICICNPGPPPPQPDPQPPTPPTFQPAPPANDQPPPPPQSTSPPPVATTPPALPPKPLPPPLSPPQTTPPPPPAITPPPPPAITPPLSPPPPAITPPPPLATTPPALPPKPLPPPLSPPQTTPPPPPAITPPLSPPLVGICSKNDTELKICAGILAISDGLLTTGRAEPCCSIIRNVSDLDAVTCFCKSVGAPRFSLSPNFGIFFKVCGRRIPQGFSCPGPSPTISPPPLPPQTLKPPPPQTTPPPPPAITPPLSPPLVGICSKNDTELKICAGILAISDGLLTTGRAEPCCSIVRNVSDLDAVTCFCKSVGARRFSLSPNFGIFFKVCGRRIPQGFSCP", "length": 375 }, "evidence": [ { "id": "G3MZM9", "url": "https://omabrowser.org/oma/group/G3MZM9/", "database": "OMA" } ], "glygen_name": "Arabidopsis", "common_name": "Mouse-ear cress" }, { "uniprot_canonical_ac": "F4K5R6-1", "protein_name": "Cell division cycle 20.6, cofactor of APC complex", "gene_name": "CDC20-6", "tax_id": 3702, "organism": "Arabidopsis thaliana", "sequence": { "sequence": "MMKSIALALCLTHHSPMVLSIVDYGDSQEKTIDSLWKKPHGSDLTWSGFSRVGVTEAYFAVPVDHFLTNPPSLRLSQTIYCRRGSSYVETEKVEEEDRDDFLKQVWFLTDNLVFFFVDIEEYIVIEQLGDTVYLWDASSCYTSKLVTIDDENGPVTSINWTQDGLDLAVGLDNSEVQVWDCVSNRHVRTLRGGHESRVGSLAWNNHILTTGGMDGKIVNNDVRIRSSIIGTYVGHTEEVCGLKWSESGKKLASGGNDNVVHIWDRSLASSNPTRQWLHRFEEHTAAVRALAWCPFQASLLATGGGVGDGKINFWNTHTGACLNSVETGSQVCSLLWSKSERELLSAHGFTQNQLTLWKYPSMVKMAELNGHTSRVLFMAQSPDGCTVASAAGDETLRLWNVFGEPPKTTKKAASKKYTEPFAHVNHIR", "length": 428 }, "evidence": [ { "id": "G3MZM9", "url": "https://omabrowser.org/oma/group/G3MZM9/", "database": "OMA" } ], "glygen_name": "Arabidopsis", "common_name": "Mouse-ear cress" }, { "uniprot_canonical_ac": "F5H284-1", "protein_name": "Peptidyl-prolyl cis-trans isomerase A-like 4D", "gene_name": "PPIAL4D", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MVNSVVFFEITRDGKPLGRISIKLFADKIPKTAENFRALSTGEKGFRYKGSCFHRIIPGFMCQGGDFTRPNGTGDKSIYGEKFDDENLIRKHTGSGILSMANAGPNTNGSQFFICAAKTEWLDGKHVAFGKVKERVNIVEATEHFGYRNSKTSKKITIADCGQF", "length": 164 }, "evidence": [ { "id": "G3MZM9", "url": "https://omabrowser.org/oma/group/G3MZM9/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "F6R3J9-1", "protein_name": "Spermatogenesis associated glutamate (E)-rich protein 1G", "gene_name": "Speer1g", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MWRARRHTSSTAPDLSKKEFKKEKERLTTELHLLIQLRNEQRDHLIDFKESSNYNRTKPTQKKNPFYEQLRSTKNQVLSSVHKLEMGIIEAQENIQELNKWIDYFTNLHSQLLMEKNLKMSITQNKKNKEVEIDWALIEKYLVDLNLNGQTGADQQP", "length": 157 }, "evidence": [ { "id": "G3MZM9", "url": "https://omabrowser.org/oma/group/G3MZM9/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "F6X687-1", "protein_name": "Spermatogenesis associated glutamate (E)-rich protein 1A", "gene_name": "Speer1a", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MWRARRHTSSTAPDLSKKEFKKEKERLTTELHLLIQLRNEQRDHLIDFKQSSNYNRTKPTQKKNPFYEQLRSTKNQVLSSVHKLEMGIIEAQENIQELNKWIDYFTNLHSQLLMEKNLKMPVTQNQKNKEVEIDWALIEKYLVDLNLNGRTGADQQP", "length": 157 }, "evidence": [ { "id": "G3MZM9", "url": "https://omabrowser.org/oma/group/G3MZM9/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "F6YNI8-1", "protein_name": "Eukaryotic translation initiation factor 4C", "gene_name": "Eif1ad19", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MPKNKGKGGKNRCRGKNENESEKRELVFKEYGQEYAQVTKMLGCGRLEAMCFDGVRRLCHIRGKLRKKVWINTSDIILVGLQDYQDNKADVILKYNLDEARSLKAYGELQEHAKINETDTFGPGDDDEIVFDDTGDDDEDIDDI", "length": 144 }, "evidence": [ { "id": "G3MZM9", "url": "https://omabrowser.org/oma/group/G3MZM9/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "F7AMQ8-1", "protein_name": "Exocrine gland secreted peptide 8", "gene_name": "Esp8", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MEKVSAMTSFPVMLFLIILLLPSICSEERTQADPTISADNKKNFKTVVDLTDCQCERNFIESLESTLPASNQDQTLFENMTNQHKLNLSKMLSVLSKCCTQKQQVDTVHFRRMPHRIQSTKQNNYKKQVLYPMQEFMNLTRDVLVSRYV", "length": 149 }, "evidence": [ { "id": "G3MZM9", "url": "https://omabrowser.org/oma/group/G3MZM9/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "F7C9P2-1", "protein_name": "F-box and WD-40 domain protein 25", "gene_name": "Fbxw25", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MEIHLPSLPMLKILSYLDAYNLLQAAQVNKNWNALASSDVLWRKLCQRRWHYCDMVTLQLQGKETWKQFFIYRIWQEHAKTRAKPEDFTYKEIPVECGFYGYACYISGHGLTRNGQGKSVICMVSSKNTISTWDIHKSVITWVSPVQPASINLLTTLPDMHIAVTVDIQSTIKLWDCHNREALATNNLESPCKSLKAVISKDGPIVLVGDTLGNLYIFRIPDLHLISTVNVFPYGFDEIDCSPQKKWVLLSKNYPHILPKVFYMSSLLRTSEFSAPVSTILEFSLCQGAFWTPRREDRITLMSRSGFPQITKFETFDMKLEGIGNKVAVQGKLIASFFLPYYEESPNWIGVSDKDVIVCSTHFFLLLFTINGLHLQTFQYCPETIVRLCVDPVHVIVTCNNGSLDVYAWEERSLLLRKCYRLQNKRPLPLYGFINNLLCDDVSIVQLMRDGHGPYSLIAYALNICS", "length": 466 }, "evidence": [ { "id": "G3MZM9", "url": "https://omabrowser.org/oma/group/G3MZM9/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "F7ELE5-1", "protein_name": "NADH dehydrogenase [ubiquinone] iron-sulfur protein 7, mitochondrial", "gene_name": "Ndufs7", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "RRTVVYTARARSQEKSGSEPLSLWFRFPLVSIWALDQNRNSLEDGPQRLSEGRGQDGGAGGSWLALCTDPGSAHRHSGSAAQSPPECGSHWEPEQSAVSKAGAGAVVPKPSHLPRSRAEYVVTKLDDLINWARRSSLWPMTFGLACCAVEMMHMAAPRYDMDRFGVVFRASPRQADVMIVAGTLTNKMAPALRKVYDQMPEPRYVVSMGSCANGGGYYHYSYSVVRGCDRIVPVDIYVPGCPPTAEALLYGILQLQRKIKREQKLKIWYRR", "length": 271 }, "evidence": [ { "id": "G3MZM9", "url": "https://omabrowser.org/oma/group/G3MZM9/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "F7F947-1", "protein_name": "Beta-defensin-like domain-containing protein", "gene_name": "Spag11b", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MDLSQRPPNVFRHVVDFLKKNQTHITQACSGNSGGRKASSSDLCGCALCLEAPSPHSQLSYKRACSSCPPTRGSSVPAVPSTAMKQRLLPSFVNLLLAALLLPGKAETWLRSWTQALSAVVTLGSSSASSINHLVTEPPSSPQDEFPAQGGNGSGLLHHRVKRFPPRTPPYHEPGPNYQIVNCKKNEGFCQKYCNFMETQVGYCSKKKEACCLHPF", "length": 216 }, "evidence": [ { "id": "G3MZM9", "url": "https://omabrowser.org/oma/group/G3MZM9/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "F7FNC4-1", "protein_name": "Interleukin 36, gamma", "gene_name": "Il36g", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MSSKYPHSPCTASGKETPDLGQVSDVDQQVWIFRDQALVTVPRSHTVTPVTVTVLPCKYPESLEQGKGTPIYLGIQNPDKCLFCKEVNGHPTLLLKEEKILNLYHHPEPMKPFLFYHTLTGATSTFESVVFPGSFIASSKIGKPIFLTSKKGEHYNIHFSLDII", "length": 164 }, "evidence": [ { "id": "G3MZM9", "url": "https://omabrowser.org/oma/group/G3MZM9/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "F8VPX6-1", "protein_name": "Spermatogenesis associated glutamate (E)-rich protein 4A1", "gene_name": "Speer4a1", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MALFARLCRLFQRANVNGRETREGRKDANLPPESNEGRRRWTWRMWMAHRQTTSSVPVTSKKQFEKEEKELIKKIQLTTKETNELRDRLIYVTEGSMNKRPYHRQTRHYKELKLKEKEIMTYLHNLEMENMEARENKQEFKKEKNFYRNLHTRILLEENLIKKKLAILQQESKEIHADWAIIQERLVELNLSCKDEQEKTSNLETQENQVSEAARELGLATAEEDSILQNELPCQEAPAEHHTQNPPSSSDESSSDESSYSTCPAWE", "length": 267 }, "evidence": [ { "id": "G3MZM9", "url": "https://omabrowser.org/oma/group/G3MZM9/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "F8VQM2-1", "protein_name": "C-C motif chemokine ligand 26", "gene_name": "Ccl26", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MFFDLGLLVLLAIFLSVQLGVATCGSSIAMSCCPNFSYYVIPWSWVYSYKFTDKSCTSDGVIFFTKTGKQFCVQPGAKWVQRFISLVNTRNHL", "length": 93 }, "evidence": [ { "id": "G3MZM9", "url": "https://omabrowser.org/oma/group/G3MZM9/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "G3GSG1-1", "protein_name": "Ferritin", "gene_name": "LOC100767129", "tax_id": 10029, "organism": "Cricetulus griseus", "sequence": { "sequence": "MGFLRKSHRRQRHRCPLRVSRATVAYPLVFMTPPIISPPSQVRQNYHFDCKTAVNNHVQLQLHNSSVYLAMAFYFDSEDVAQKNLASFFLNKSHECTAQAEMFLELQNQRGGRISLGSIREADRNNWLGGLQAMECALQLELSTNQSLVALHQLASSKSDAHLCSFLKNHFLTKQVEVLKEISGYVTKLRQMGSPDDGIAEYLFGKLTLDDNKGK", "length": 215 }, "evidence": [ { "id": "G3MZM9", "url": "https://omabrowser.org/oma/group/G3MZM9/", "database": "OMA" } ], "glygen_name": "Hamster", "common_name": "Chinese hamster" }, { "uniprot_canonical_ac": "G3GWA3-1", "protein_name": "60S ribosomal protein L18a", "gene_name": "LOC100764432", "tax_id": 10029, "organism": "Cricetulus griseus", "sequence": { "sequence": "MKASGTLREYKVVGRCLLTPKCHTPPLYLMRIFALNHVVAKSRFWSQLKKMKSSGEIVHCGEVRPEVPLQVKNFAIWLHYDSRNGTYNMCREYWDLTVTQCYRDMGAQHCARTHCIHIMKVEEIASGKCQRPAVKQFHDSKIKFLLPHRVLRCQHKPHFTTKRLNTFF", "length": 168 }, "evidence": [ { "id": "G3MZM9", "url": "https://omabrowser.org/oma/group/G3MZM9/", "database": "OMA" } ], "glygen_name": "Hamster", "common_name": "Chinese hamster" }, { "uniprot_canonical_ac": "G3H156-1", "protein_name": "Prefoldin subunit 4", "gene_name": "LOC100773780", "tax_id": 10029, "organism": "Cricetulus griseus", "sequence": { "sequence": "MVATMKKAAAEDVNVTFEDQQKINKFARDTSRITEQKEIEVKKNHLQNLEDTFNDIMLADGDCFMTQYLIRDVLISHSQEEAQEMLEEAKKTLQEEIDALESRVGAIQWVLANLKVQLYTKFGSNINLGVDES", "length": 133 }, "evidence": [ { "id": "G3MZM9", "url": "https://omabrowser.org/oma/group/G3MZM9/", "database": "OMA" } ], "glygen_name": "Hamster", "common_name": "Chinese hamster" }, { "uniprot_canonical_ac": "G3H2T6-1", "protein_name": "Histone H4", "gene_name": "LOC100757199", "tax_id": 10029, "organism": "Cricetulus griseus", "sequence": { "sequence": "MSGRGKGGKGLGKGGAKRHRKVLRDNIQGITKPAIRRLARRGGVKRISGLIYEETRGVLKVFLENVIRDAVTYTEHAKRKTVTAMDVVYALKRQGRTLYGFGG", "length": 103 }, "evidence": [ { "id": "G3MZM9", "url": "https://omabrowser.org/oma/group/G3MZM9/", "database": "OMA" } ], "glygen_name": "Hamster", "common_name": "Chinese hamster" }, { "uniprot_canonical_ac": "G3H8X2-1", "protein_name": "1-acyl-sn-glycerol-3-phosphate acyltransferase gamma", "gene_name": "Agpat3", "tax_id": 10029, "organism": "Cricetulus griseus", "sequence": { "sequence": "MGLLAYLKTQFVVHLLIGFVFVVSGLVINFTQLCTLALWPISKQLYRRINCRLAYSLWSQLVMLLEWWSCTECTLFTDQATVDHFGKEHAVIILNHNFEIDFLCGWTMCERFGVLGSSKVLAKRELLCVPLIGWTWYFLEIVFCKRKWEEDRDIVKEGLQCLSDYPEYMWFLLYCEGTRFTETKHRISMEVAASKGLPPLKYHLLPRTKGFTTTVQCLRGTVAAIYDVTLNFRGSKNPSLLGILYGKKYEADMCVRRFPLEDIPADENDAAQWLHKLYQEKDALQEMYKQKGVFPGEPIKPARRPWTLLNFLCWATILLSPLISFVLGVFASGSPLLILTFLGFVGAASFGVRRLIGVTEIEKGSSYGNQELKKKE", "length": 376 }, "evidence": [ { "id": "G3MZM9", "url": "https://omabrowser.org/oma/group/G3MZM9/", "database": "OMA" } ], "glygen_name": "Hamster", "common_name": "Chinese hamster" }, { "uniprot_canonical_ac": "G3HAB3-1", "protein_name": "40S ribosomal protein S15", "gene_name": "LOC100759804", "tax_id": 10029, "organism": "Cricetulus griseus", "sequence": { "sequence": "MAEVEQKKKRTFRKFTYCGVDLDQLLDMSCEQLMQLCSTRQRLLLNCSLWRKQHSLLKSLRKAKKKVPPMEKPEVGKTHLRDMIILPEMAGSMVDVYNGKTFNQVEIKPKMIGHYLGEFSITYKPVKHGGPGVGATHSSRFIPLK", "length": 145 }, "evidence": [ { "id": "G3MZM9", "url": "https://omabrowser.org/oma/group/G3MZM9/", "database": "OMA" } ], "glygen_name": "Hamster", "common_name": "Chinese hamster" }, { "uniprot_canonical_ac": "G3HDI6-1", "protein_name": "Lipid transferase CIDEB", "gene_name": "Cideb", "tax_id": 10029, "organism": "Cricetulus griseus", "sequence": { "sequence": "MEYLSALNPNGLLRSVSTMGSELGRRVWNSGPPPQRPFRVCDHKRTVRKGLTAATRQELLDKVLETLLLSGVLTLVLEEDGTAVESEDFFQMLEDDTCLMALERGQSWSPRSGMLSYGLGREKPKHSQDIARITFDVYKQNPRDLFGSLNVKATFYGLYSMSCDFQGVGPKKVLRELLRWTSSLLQGLGHMLLGISSTLRHVVEGAERWQWHKQNHLRS", "length": 219 }, "evidence": [ { "id": "G3MZM9", "url": "https://omabrowser.org/oma/group/G3MZM9/", "database": "OMA" } ], "glygen_name": "Hamster", "common_name": "Chinese hamster" }, { "uniprot_canonical_ac": "G3HDS5-1", "protein_name": "Histone H3", "gene_name": "LOC100773314", "tax_id": 10029, "organism": "Cricetulus griseus", "sequence": { "sequence": "MARTKQTARKSTGGKAPRKQLATKAARKSAPATGGVKKPHRYRPGTVALREIRRYQKSTELLIRKLPFQRLVREIAQDFKTDLRFQSSAVMALQEASEAYLVGLFEDTNLCAIHAKRVTIMPKDIQLARRIRGERA", "length": 136 }, "evidence": [ { "id": "G3MZM9", "url": "https://omabrowser.org/oma/group/G3MZM9/", "database": "OMA" } ], "glygen_name": "Hamster", "common_name": "Chinese hamster" }, { "uniprot_canonical_ac": "G3HGI3-1", "protein_name": "PHD finger protein 6", "gene_name": "Phf6", "tax_id": 10029, "organism": "Cricetulus griseus", "sequence": { "sequence": "MSSSIEQKKGSTRQRKCGFCKSNRDKECGQLLVSENQKVAAHHKCMLFSSALVSSHSDNESLGGFSIEDVQKEIKRGTKLMCSLCHCPGATIGCDVKTCHRTYHYHCALHDKAQIREKPSQGIYMVYCRKHKKTAHNSEADLEETFNEHELEPSSPKTKKKSRKGRPRKTNFKGLTEDSRSTSSHGTDEMESSSYRDRSPHRSSPNDTRPKCGFCHVGEEETEARGKLHIFNAKKAAAHYKCMLFSSGTVQLTTTSRAEFGDFDIKTVLQEIKRGKRMKCTLCSQPGATIGCEIKACVKTYHYHCGVQDKAKYIENMSRGIYKLYCKNHSGNDERDEEDEERESKSRGRLAIDQQLTQQQLNGN", "length": 364 }, "evidence": [ { "id": "G3MZM9", "url": "https://omabrowser.org/oma/group/G3MZM9/", "database": "OMA" } ], "glygen_name": "Hamster", "common_name": "Chinese hamster" }, { "uniprot_canonical_ac": "G3HJW3-1", "protein_name": "Calcium homeostasis modulator protein 6-like", "gene_name": "LOC100774768", "tax_id": 10029, "organism": "Cricetulus griseus", "sequence": { "sequence": "MEKFKAVLDLQSKHRSALGYGLVTLLTAGGEKIFSEVVFQCPCSATWNLPYGLVFLLVPALALFLLGYALRTRTWRLLTGCCSWSASAQSSSGLQRVFVCAQISAAAALPPLTWVAVALLGGSFYQCAVSGSEAMARHLCKGRDPSCAAKLPQVPCKKQEAEMQDILSQLKAQSQVLGWILIAAIIILLLVVKSVTRCLSPVSYLQLKFWEIYLEKERQILQGEAMEHATQLAKENVRCFFDCTNPKDCSTPSSKAWQQISALYTFNPKNHFYSMLHKYVNRKDMSGSLRSVEGDAVVPVLGFVDASGMATTHGV", "length": 315 }, "evidence": [ { "id": "G3MZM9", "url": "https://omabrowser.org/oma/group/G3MZM9/", "database": "OMA" } ], "glygen_name": "Hamster", "common_name": "Chinese hamster" }, { "uniprot_canonical_ac": "G3HQ40-1", "protein_name": "Eukaryotic peptide chain release factor GTP-binding subunit ERF3B", "gene_name": "LOC100767578", "tax_id": 10029, "organism": "Cricetulus griseus", "sequence": { "sequence": "MDLGSSSDSAPDCWDQVDMEVPGSAPSGDGFTSASTAAAEAAEAEAQRQHLSMAFSSQLNIHAKPFVPRVSAAEFVQSFLPGSAQPPAPTTSSSDETCTGAGDPQGKRLGWGAPVEPSKDGPLMSWEGSNSAVTMELSEPVVENGEVEMALEESWELKEVSEAKPGGSLGDSGPPEESGKEMMEEKEVIRKSKSMAIPSGAPKKEHVNVVFIGHVDAGKSTIGGQIMFLTGMVDRRTLEKYEREAKEKNRETWYLSWALDTNQEERDKGKTVEVGRAYFETEKKHFTILDAPGHKSFVPNMIGGASQADLAVLVISARKGEFETGFEKGGQTREHAMLAKTAGVKYLIVLINKMDDPTVDWSSERYEECKEKLVPFLKKVGFSPKKDIHFMPCSGLTGANIKEQSDFCPWYTGLPFIPYLDSLPNFNRSIDGPIRLPIVDKYKDMGTVVLGKLESGSIFKGQQLVMMPNKHNVEVLGIVSDDAETDFVAPGENLKIRLKGIEEEEILPGFILCEPSNLCHSGRTFDVQIVIIEHKSIICPGYNAVLHIHTCIEEVEITALISLVDKKSGEKSKTRPRFVKQDQVCIARLRTAGTICLETFKDFPQMGRFTLRDEGKTIAIGKVLKLVPEKD", "length": 631 }, "evidence": [ { "id": "G3MZM9", "url": "https://omabrowser.org/oma/group/G3MZM9/", "database": "OMA" } ], "glygen_name": "Hamster", "common_name": "Chinese hamster" }, { "uniprot_canonical_ac": "G3HQN5-1", "protein_name": "Transcription factor 19 isoform X1", "gene_name": "Tcf19", "tax_id": 10029, "organism": "Cricetulus griseus", "sequence": { "sequence": "MLPCFQLLRIGGGRGGDLYTFHPPSRSGCTYRLGCRADLCDVALRPQQEPGLISGVHALLHAELQGDDWRVSLEDHSSQGTLVNNVRLPRGHRLELSDGDLLTFGPEGQAGTSSSEFYFMFQQVRVKPQDFAAITVPRSRGEAGTGFQPMVPSQGAPQRPLSTLSSAPKATLILNSIGSLSKLQPQPLTFSRGGGRPQSLAVPTQPGEVGASPPAPPTRNRRKSVHRVLAELDDENETSLSPLSVLMEPRKKLRLEKAALVSSGRD", "length": 266 }, "evidence": [ { "id": "G3MZM9", "url": "https://omabrowser.org/oma/group/G3MZM9/", "database": "OMA" } ], "glygen_name": "Hamster", "common_name": "Chinese hamster" }, { "uniprot_canonical_ac": "G3HWQ5-1", "protein_name": "Zinc finger protein 219", "gene_name": "Znf219", "tax_id": 10029, "organism": "Cricetulus griseus", "sequence": { "sequence": "MEGSRPRILVGHLEPSPPAFDGELDLQHYSNGPGVSTGSPGMGAVGWSETRAGERRFPCPVCGKRFRFNSILALHLRAHPGAQAFQCPHCGHRAAQRALLRSHLRTHQPERPRSPAARLLLELEERALLREAQLGRARSSGGMQATPATEGLARPQVPSSSAFPCPFCKGKFRTSAERERHLHILHRPWKCSLCSFGSSQEEELLHHSLTAHGASERPLAATSTPEPQPPPQPEPRSALEPEPEPEPRPEPEHEANPAPTPAPPEEPPAPPEFRCQVCGQSFTQSWFLKGHMRKHKASFDHACPVCGRCFKEPWFLKNHMKVHTSKLGPLRAPGPGSTPARAPQPPDMSLLAYEPLGPALLLAPAPTPAERREPPSLLGYLSVRAGEVRPNGEGADPGAGRSYGGGFRPLPSALPNRARRHRTEEPEEEEEVVEAEEESWARGRSLGTLTSLHPHPGEGSGQSAPAVGAQARPTGTQEENGLLVGGARSEAGRGATGKDCPFCGKSFRSAHHLKVHLRVHTGERPYKCPHCDYAGTQSGSLKYHLQRHHREQRSSAGPGPPPEPPPPSPRGAASLQPQSGAKPTQASATWVEGTASTRPSSSGTGAGSRRKPASPGRTLRNGRGGEAEPLDLSLRAGPGGEAGSGGALHRCLFCPFATGAPELMALHLQVHHSRRARGRRQPRADTSPPYVRAPSGETPPSPPLEEEGSPGLSRSGEAGLGGQER", "length": 725 }, "evidence": [ { "id": "G3MZM9", "url": "https://omabrowser.org/oma/group/G3MZM9/", "database": "OMA" } ], "glygen_name": "Hamster", "common_name": "Chinese hamster" }, { "uniprot_canonical_ac": "G3I071-1", "protein_name": "Large ribosomal subunit protein uL29", "gene_name": "LOC100753244", "tax_id": 10029, "organism": "Cricetulus griseus", "sequence": { "sequence": "MAKIKARDLRGKKEELLKQLDDLKVELSQLRVAKVTGSAASKLSKIRVVQKSIVRVLTVINQTQKENLRKFYKGKKYKPLDLRPKKTRAMHRQLTKHEEKLKTKKQQRKERLYPLRKYAFKA", "length": 122 }, "evidence": [ { "id": "G3MZM9", "url": "https://omabrowser.org/oma/group/G3MZM9/", "database": "OMA" } ], "glygen_name": "Hamster", "common_name": "Chinese hamster" }, { "uniprot_canonical_ac": "G3I1Z3-1", "protein_name": "DNA damage-inducible transcript 4 protein", "gene_name": "Ddit4", "tax_id": 10029, "organism": "Cricetulus griseus", "sequence": { "sequence": "MPSLWDRFSSSSSSSSSSSSGTPATDRPPRSAWGSAAREEGLDRCASLESSDCESLDSSNSGFGPEEDSSYLDGVSLPDFELLSDPEDEHLCANLMQLLQESLSQARLGSRRPARLLMPSQLVSQVGKELLRLAYSEPCGLRGALLDVCVEQGKSCHSVAQLALDPSLVPTFQLTLVLRLDSRLWPKIQGLLSSANSSLVPGYSQSLTLSTGFRVIKKKLYSSEQLLIEEC", "length": 231 }, "evidence": [ { "id": "G3MZM9", "url": "https://omabrowser.org/oma/group/G3MZM9/", "database": "OMA" } ], "glygen_name": "Hamster", "common_name": "Chinese hamster" }, { "uniprot_canonical_ac": "G3IAH8-1", "protein_name": "Guanine nucleotide-binding protein subunit gamma", "gene_name": "LOC100755128", "tax_id": 10029, "organism": "Cricetulus griseus", "sequence": { "sequence": "MASNNTASIAQARKLVEQLKMEANIDRIKLSKAAADLMACCAAHAKEDPLLTPVPASENPFREKSFCTIL", "length": 70 }, "evidence": [ { "id": "G3MZM9", "url": "https://omabrowser.org/oma/group/G3MZM9/", "database": "OMA" } ], "glygen_name": "Hamster", "common_name": "Chinese hamster" }, { "uniprot_canonical_ac": "G3IG76-1", "protein_name": "Olfactory receptor 7E24 isoform X2", "gene_name": "LOC100765597", "tax_id": 10029, "organism": "Cricetulus griseus", "sequence": { "sequence": "MYILALFGNLLIILTVSSDSHLHTPMYFFLSNLSMIDIGYISTTVPRVIVDIQTHCPVISYVGCLTQMSLIIIFACMDDMLLSVMAYDRFVAICHPLYYQVIMNPSSCGVLLLGSFLLSLVNLLLHYVAVLSFSNCEDIFEISNFFCGPSELFKLACFDTFTTNIVRYCAGALFGLLPISGIIFSYFKIVSSIMRSSSSSNGKWKTFSTCGSHLSIVCLFYGTALGMYFSSSLSLSPKTNAVASVMYTVVTPMLNPFIYSLRNKDIKTALRKILSRTF", "length": 278 }, "evidence": [ { "id": "G3MZM9", "url": "https://omabrowser.org/oma/group/G3MZM9/", "database": "OMA" } ], "glygen_name": "Hamster", "common_name": "Chinese hamster" }, { "uniprot_canonical_ac": "G3IGD7-1", "protein_name": "Olfactory receptor", "gene_name": "LOC100770882", "tax_id": 10029, "organism": "Cricetulus griseus", "sequence": { "sequence": "MSGANSSSLTPEFFVLNGIPGLEDAHVWISLPFCFMYMIAVVGNCGLMYLIGHEEALHRPMYYFLTLLSFTDITLCTTTVPNTLCIFWFNLKKIGFKACLAQMFFVHTFTATESGMLMLMALDRYVAICYPLRYGTILTNPVIAKASLATFLRSVAFILPFTFLTKRLPYCRGNTIPHAYCDHMSVAKISCGNVKVNAIYGLLVALVVCAFDIFCITVSYTMILRAVMNLSSADARHKAFSTCTSHICAIVITYVPAFFNFFTHRFGGHTIPHHIHIIVANLYLLLPATMNPIVYGVKTKQIRESVIKFFSGDKSGITEIKGLQNK", "length": 326 }, "evidence": [ { "id": "G3MZM9", "url": "https://omabrowser.org/oma/group/G3MZM9/", "database": "OMA" } ], "glygen_name": "Hamster", "common_name": "Chinese hamster" }, { "uniprot_canonical_ac": "G3INQ1-1", "protein_name": "Olfactory receptor", "gene_name": "LOC100763177", "tax_id": 10029, "organism": "Cricetulus griseus", "sequence": { "sequence": "MFCNTSTPGHSTFLLTGFPGLEASHHWVSIPINLICVVSILGNSIILFLIRTDPALHEPMYIFLSMLAASDLGLCASTFPTMVRLFWLGIRELPFDLCAAQMFFIHAFTYVESGVLLAMAFDRFIAIRDPLHYATILPHSAVAKVGAAVLIRAILLNLPGPILLRRLLFPQVSVLSHCYCLHCDLVGLACSDTRINSLVGLVSILLSLGLDSSLIMLSYVLILRTVLSIASPGERLKALNTCVSHLCIVLIFYLPKLGLSVLHRVEKHSYPALAVLMANLHFLVPPFMNPVVYCIKSKQIRQGFLKRFQQKRVDVS", "length": 316 }, "evidence": [ { "id": "G3MZM9", "url": "https://omabrowser.org/oma/group/G3MZM9/", "database": "OMA" } ], "glygen_name": "Hamster", "common_name": "Chinese hamster" }, { "uniprot_canonical_ac": "G3MYE2-1", "protein_name": "Large ribosomal subunit protein uL18", "gene_name": "", "tax_id": 9913, "organism": "Bos taurus", "sequence": { "sequence": "MGFVKVVKNKAYFKRYQVKFRRRQEGKTDYYARKRLVIQDKNKYNTPKYRMIICVTNRDIICQIAYARIEGDMIVCAAYAHELPKYGVKVGLTNYAVAYCTGLLLACRLLNRFGMDKIYEGQVEVTGDEYNVESIDGQPGALTCYLDAGLARTTTGNKFFGALKGAVDGGLSIPHSTKQFPGYDSESKEFSAEVHRKHIMGQNVADYMRYLTEDEDAYKKQFSQYIKNNVTPDMEEMYKKAHAAIRENPVYEKKPKKEVKKKRWNRPKMSLGQENDRVAQKKASFLRAQERAAES", "length": 295 }, "evidence": [ { "id": "G3MZM9", "url": "https://omabrowser.org/oma/group/G3MZM9/", "database": "OMA" } ], "glygen_name": "Bovine", "common_name": "Bovine" }, { "uniprot_canonical_ac": "G3UW31-1", "protein_name": "Vomeronasal type-1 receptor", "gene_name": "Vmn1r176", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MLSQNKSVKTTVEVTLQILLLCQVGVGTVVNIFLFVHNLSPFLNGSQQRPIKVILANLALGNTLILLFAFPNNIRVFIPREFPTDLKCKLGYFIWLVARSTNMCSTCSLSTYQFVTLAPGTWGRVMLPGRAPNFLRYTCYSCWLFSVLNNAHIPMKVSGPQKTHNDSNSKSKWVCSTSGFSIGMRILSFAHDAVFISIIIWSSVSMVILLNRHHQRLQHIQSTNQKLRVHAETRASHTILLLVVTFVTCYLLDCICTVCNISFVDSRVWLRRVKEILSVSFPTFSPLLLIFRDPKDPCSLLFGC", "length": 304 }, "evidence": [ { "id": "G3MZM9", "url": "https://omabrowser.org/oma/group/G3MZM9/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "G3UY92-1", "protein_name": "Vomeronasal type-1 receptor", "gene_name": "Vmn1r158", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MSAHGKSVKTTEEVALQLLLLCQFGVGTVAKVFLFVRNFSPVLTGSKQRPRQVILSHMAVANALTLFLTIFPNNMMAFAPKTPPTELKCKLESFSHLVARSTNLCSTCVLSFHQFVTLVPLNRGKGKLVLRASVTNMASYSSYSCWFFSVLSNIHIPIKVSGPQIKDNNTDSNRKLFCSTSGFSVGTVLLQFAYDATFMSIMVWASVSMVLLLHRHRQRMQHILTPNQDARGQAESRATRTILMLVVTFVSFYLLNFICIMLHALFMHSHFFVRLVSEILTAVFPSISPLLLIFRDPKDPCSVLFNC", "length": 307 }, "evidence": [ { "id": "G3MZM9", "url": "https://omabrowser.org/oma/group/G3MZM9/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "G3V9M0-1", "protein_name": "Cystatin S like 1", "gene_name": "Cyssl1", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MACLLYTQLFLLNTFILFLNLSLNPVLGQILAGIEKSIIEEEGALEALNFAVSEYNENNSDLYLSRVVEVKTVKTVQQQIEAGKTLLFDVILGKTACLKTQDDLSDCPLNEPTDLQEREFCSFEVHLPDWANAINLLSSICNRI", "length": 144 }, "evidence": [ { "id": "G3MZM9", "url": "https://omabrowser.org/oma/group/G3MZM9/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "G3X693-1", "protein_name": "Ig-like domain-containing protein", "gene_name": "", "tax_id": 9913, "organism": "Bos taurus", "sequence": { "sequence": "RVFLPLLLLGVILPGGDNEDGPTSFHLIQISTFVNNTWAQNQGSGWLDDLQIHGWESDSGTAIFLKPWSKGNFSDDEVTELVDLFRAYFIGFTREVQDRVNEFQLEYPFVIQVTAGCELHSGEAIESSLRGALGGLDFVSIQNHSCVPAPDGSSRGQKFCALTTQYQGISDIIERLLSETCPRYLLGVLDAGKAELQRQVKPEAWLSSGPTPGPGRLLLVCHVSGFYPKPVRVMWMRGEQEQPGTQQGDLMPIGEAAGLNCRVKHSSLGDQDIILYWGHPTSIGLILVAIIVPSLILLICLAFGVLRFMGSHRIGHD", "length": 317 }, "evidence": [ { "id": "G3MZM9", "url": "https://omabrowser.org/oma/group/G3MZM9/", "database": "OMA" } ], "glygen_name": "Bovine", "common_name": "Bovine" }, { "uniprot_canonical_ac": "G3X9Q9-1", "protein_name": "Predicted gene 6526", "gene_name": "Gm6526", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MFSWLRRLFHRENGDQGETRPRQKESAIPSCKKRRMKSFWGRHMSAGKKSSQNCNITNHMKNMNKLEDMKFYIRKINAKRLELFPILDIDMNTDLNYRMNIEFTIIKSQHEKTMLDMEKMTQSISDTIETYKEFIEDKDSYSFTHSYLLKECNQLKEKVRMLLNENRKLLVEQADQEASYGEEKRFCDESSKNIHPKC", "length": 198 }, "evidence": [ { "id": "G3MZM9", "url": "https://omabrowser.org/oma/group/G3MZM9/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "G5E8X8-1", "protein_name": "Oocyte maturation, alpha", "gene_name": "Omt2a", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MDTLVFTKVHLESWVYKGLRGQHDSILELLKENLHHYLCIEFDEGLNDTVVYIIGFKFFAMFAMFVIVSLACNLRTKRNRARAWARGLQSPVWWNRRYFI", "length": 100 }, "evidence": [ { "id": "G3MZM9", "url": "https://omabrowser.org/oma/group/G3MZM9/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "H3BJ46-1", "protein_name": "Vomeronasal type-1 receptor", "gene_name": "Vmn1r14", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MSSLSFMSSLLENILYFQAGLGVLANIFLLVFYIFIILGHRPKPMDLISCQLTFVHIMMFLAGENFWLANIFESLNVENDFKCKATFYTKRVMRGLSICITCLLSVFQAVMISHRNSLLAKFKHKLKIYMINALFYIWTFNLSLSSNLIFYVGGFTNMSQTKQLKVTKSCSLIPMNYIIRGLILTVISSRDMFLVGVMLTTSTYMVIILCRHQRQCKHLHSTSHLRASPEKRATQTILLLVVFFVIMYWVDFIISSTSILLWMYDPVIMIVQKFVVNAYPAITPFVQISSDTRVIRVVKNWHS", "length": 303 }, "evidence": [ { "id": "G3MZM9", "url": "https://omabrowser.org/oma/group/G3MZM9/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "H3BJ88-1", "protein_name": "Vomeronasal 2, receptor 3", "gene_name": "Vmn2r3", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MKMAIRKKCLILELTVFLCVELYAQYEDQNMTCRLMRKFNLTGYVEAENHHFVIGGQFPVHYRTIPTSDSDEEPESPMCEGFNFRGFRWMKTMIHTIKEINERKDILPEHTLGYQIFDNCFSTTKAMESSMVFLTGQDEYKPKWRNSTGKYLIGIIGAGGSTMSLAGARILLLNDVVQVGYASSSSILTEYLNVYRTIPSDKFQTEAIVNLIRHFGWVWIGAIASDDDYGKHGVKSFRKILETNNLCIAFSETIPKVYSNEKMQIAIDAVKSSTAKVIVLYATDFDLSPFVLEVIHHNIAHRTWIATEAWITSALIAKPEYFPYFGGTIGFAIPRSVIPGLKEFLYDVHPSKDPNDVLTIEFWQTAFNCTWPNSSVPYNVDHRVNMTGKEDRLYDMSDHLCTGKEKLKDLKNTYLDTSQLRITNNVRQAVYLMAYGLDRLIRVLIKEYREYLLHPKILAFMSYKLFEYIRKVKFTTHDGRKIELNVHGDIENGYYDILNWQMDNTGDIAIVKVGEYKFTRSKYELVLPKNSTLFWNTESSRLPDSVCTKVCPPGTRKGFITGQPVCCFDCIPCEDGYVSEKPGQRLCNPCSEDDWSNAEKNKCVPKHVEFLAYEEALGFTLVILSIFGALVVLAVTVVYVIHRHTPLVKANDRELSFLIQISLVITVLSTMLFIGKPCNWSCMARQVTLALGFCLCLSSILGKTISLFFAYRISISKTQLISMHPSFRKLIVLLCVFGEIGVCASYLVLKPPSMFKNIERQNVKIIFECNEGSVEFLCSIFGFDVLLALLCFVTTFMARQLPDNYYEGKCITFGMLFFFIVWISFVPAYLSTKGKFKVAVEIFAILASSYGLLGCLFLPKCFIILLRPKRNTDETVGGRVPTVDRSIQLTSASVSSELNSTMVSTVLDE", "length": 909 }, "evidence": [ { "id": "G3MZM9", "url": "https://omabrowser.org/oma/group/G3MZM9/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "H3BKT1-1", "protein_name": "piRNA-mediated silencing protein C19orf84 homolog", "gene_name": "Gm52993", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MDELEDGALSNGDNLSLPSAGTESWPTSATPGLPPSLLSTLDPTHLGLPEQLASVTVPIRLDTLSYLLHSALLGTYNLQQSLPPCSCTAQPSHIWPDTVRRPPRRSGQARGGWEVRRRPSRGWGRGRGRGRVWAQSQRGPERAEERERNMAGEPGAGPSTPPVTPPSQDGQKEAGGLSEDWEADY", "length": 185 }, "evidence": [ { "id": "G3MZM9", "url": "https://omabrowser.org/oma/group/G3MZM9/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "H3BLP0-1", "protein_name": "Vomeronasal type-1 receptor", "gene_name": "Vmn1r25", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MSSLTNILYFQAGLGILANTFLLCFYTFTILCHRSKPMDLTSCQLTLAHILFLLAGGDNWLAVILESLNIENDFKCKAIFYTNRVMRGFSICITCLLSVFQAVTISPHTSLLAKFKHKLKTYIIYAVFYIWFYNFLVCSHLLVYVGGFNNVSETNQMRVTESCSLFLMNYIISGLIFTVTTFRDVFLVGVMLITNAYIVIILFRHQRHCKHLHSIRHLRVSPEKRATQTILLLMVFFVVMYWVEIIISSTSLLLWMYDPGFLTVQKLIVTVYPTITPLVQISSDKRVINVLKNLQSKCQQIF", "length": 302 }, "evidence": [ { "id": "G3MZM9", "url": "https://omabrowser.org/oma/group/G3MZM9/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "I3ITL1-1", "protein_name": "Gap junction protein", "gene_name": "gjc4a.2", "tax_id": 7955, "organism": "Danio rerio", "sequence": { "sequence": "MSWDFLTHLLDEISNHSTFVGKIWLTLLIVFRIVLTVVGGETIYDDEQSEFVCNTLQPGCKNVCYDAFAPLSHVRFWVFQIIMISTPSVMYLGFAMHKIARMADNEYQPRKHKMLSTVHQRMNRDYDMVDEMTEEVPMIPEEIEPSEKDNKSAASTKTTAASDAAVKHDGRRRIKRDGLMKVYVLQLISRVAFEIAFLFGQCILYGFEVSPSYICTRSPCPHTVDCFVSRPTEKTIFLLIMYVVSVLCLALTVLEILHLGIGGLRDSFRSRANRRLPVHRPSTSTICHRLSSAPPGYQAVQKKYSSGKLKAEFLSDSGRESLADDNTTRDLDRLRRHLKIAQQHLDQAYHTEEVGASHNSGPDSKSIAAEQNRLNQAQGGFGSTEEKVFKEAHA", "length": 394 }, "evidence": [ { "id": "G3MZM9", "url": "https://omabrowser.org/oma/group/G3MZM9/", "database": "OMA" } ], "glygen_name": "Zebrafish", "common_name": "Zebrafish" }, { "uniprot_canonical_ac": "I3L8A5-1", "protein_name": "Olfactory receptor", "gene_name": "", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "FPSRQERTMRRENQSSISEFLLLGLPIPPEQQGVFFALFLGMYLTTMLGNLLIILLIRLDPRLHTPMYFFLSHLALTDISFSSVTVPKMLMNMQTQDQSIPYAGCVTQMYFFMFFACLDNFLLTSMAYDRYVAICHPLRYTSIMRGGLCTLLVTVSWILSCANALCHTLLLAQLSICAENTIPNFFCDLGALLKLSCSDTSFNDLAIFIAGVATIMLPLLCILVSYGHIGATILKIPSTKGICKALSTCGSHLSVVFLYYGTIIGLYLVPSSSTSSHKDIVASVMYTVVTPLLNPFIYTLRNRDMKGALEKLFHKAPVLS", "length": 320 }, "evidence": [ { "id": "G3MZM9", "url": "https://omabrowser.org/oma/group/G3MZM9/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "I3L8Z8-1", "protein_name": "LRRC37A/B like protein 1 C-terminal domain-containing protein", "gene_name": "LOC100514982", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MMTLELEKLILPSHMACCLCQFKSNIEVVCKTVKLHCDRCLKNSTRCDKETSLGDVEGSFMKVLQARKKNTSTELMIEPERPSSDKSGVSLSSFMNEQLDFSDESDVISALNYILPYFSEGNLEDVESTLLPFIQLLFSNVAEADIPPGHLKTHTGNPPVNPESGTSGYTNKLRQLRFLENLLDAEIQEKIDEVMKKEKTAMLIYSNILSPKLRRQILRKKLETARTQAESLEEIESVDKRPLKVNRVLKGPRGIKKRHFRAMRRQSIRRKETAQPFVETTTKGSKLGGPSARELEQLWVVQRPRKRVADSLQKEPSFGREHKAEVSSFLKQYSRGRPAASIHPKAPATVKKTSEDLSDTLFVLVDANARVKNRKASETISYPRKIDSFHPSHSPVLHRTPEPQNRQAFRDKGSSYRLLLALRPLSSAVRSLINSPSQEASSPSGELTLQEQPSPESFSPSEPSTEHIISEKDTPQVVFEELPTSGTTTLSGPIPGPTAQGTLPTEYSATTADNVMPTGQHTSAIQWEHHNVGTDVASTPTSFISPGVSSPGSQFEAQLNQQLQSLIPNNDVRRLISHVIRTLKMDCSEPQVQLACAKLISRTGLLMKLLSEQQEAKASKAEWDTDQWKTENYINENTEAQGEQKESSELTKDVPGYGYNNKLILAISVAVVLMLLIVILCLIEVYSRRRTLREGKVGRRRGFFGFLLRKRRSGESESEGFFWRRRPLWLRDTYRPLSATRKKNMAEKLHDKESSDEEEIFHKGAGEVSEAPADVILTIESDVEDLGEETDTAPEGPPE", "length": 799 }, "evidence": [ { "id": "G3MZM9", "url": "https://omabrowser.org/oma/group/G3MZM9/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "I3LBH4-1", "protein_name": "Large ribosomal subunit protein uL11", "gene_name": "", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MPPKFNPNEIKAMYLRCTSGEISAKSALAPKIGPLGLSPKEVGDDIAKAAGDWKGLRITVKPTIQNRQAQMEVVPSASALIIKAPKELPRDRKKQKNIKHSGNITFDEIVNIARQMRRCSLARELSGTIKEILGTAQSVGCNVNGRRPHDIIDDISSGAVECQAS", "length": 165 }, "evidence": [ { "id": "G3MZM9", "url": "https://omabrowser.org/oma/group/G3MZM9/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "I3LC12-1", "protein_name": "Olfactory receptor", "gene_name": "", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MFGANLTIFHPTVFILLGMPGLEIYHTWLSIPFCLMSIVAVLGIGALILVVLSESTLHEPMHVFLSMLAGTDNLLSTTTVPKALAIFWFHAGEIAFDACITQMFFIHVAFVAELGILLAMAFDRYVAICALLRYTAVLTPSTIVKLTLAIWGWGIGTIFPIIFLLKRLPYCRTNIIPHSYCEHIGVARLACADITVNIWYGFSVPMASVLVDVAFIAVSYTLILQAVFRLPSQDAQHKALNTCGSHIGVILLFFIPSFFTFLTHRFGKNIPHHIHILLANLYVLIPPMLNPIIYGAKTKQIRDSLAHMLSRVGMS", "length": 315 }, "evidence": [ { "id": "G3MZM9", "url": "https://omabrowser.org/oma/group/G3MZM9/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "I3LEQ2-1", "protein_name": "All-trans retinoic acid induced differentiation factor", "gene_name": "ATRAID", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MARPGFRSPSSLVPRAAALLLVLSVPRALALPEICIQCPGDVQNLSEVALYCKQTPELMLQGRCCLNGKGTILGLDLQNCSLKDPGPDFAQAHTAVIIDLQANPFEGDWANTFRGFTQLQTLILPQGVNCPGGINAWDVVTFYITNQTCQGQRTFATALGTQKRVLRMDLVLLMVLVSCSVFVLMASMATSVCARAHSHCSCSSVFWDPQHYPFPSCFGGLNAEKPRLHEPQRSSY", "length": 236 }, "evidence": [ { "id": "G3MZM9", "url": "https://omabrowser.org/oma/group/G3MZM9/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "J3QM75-1", "protein_name": "Secretoglobin, family 2B, member 19", "gene_name": "Scgb2b19", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MKGTLLLLGLLITGELSFQTTEACVPFFEGYASVVSGSRVWLYHELQSFDATAEEKVALEKIQGCYREERLRNILLEPKIMEAMVASPECRSYYSLNNFRSILDFISNLLGE", "length": 112 }, "evidence": [ { "id": "G3MZM9", "url": "https://omabrowser.org/oma/group/G3MZM9/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "J3QMG8-1", "protein_name": "T cell receptor alpha variable 13N-3", "gene_name": "Trav13n-3", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MKRLLCSLLGLLCTQVCWVKGQQVQQSPPASLVLQEGENAELQCTYSTTLNSMQWFYQRPGGRLVSLLYSPSWAEQRGGRLTSSAASNESRSSLHISSSQITDSGTYLCAME", "length": 112 }, "evidence": [ { "id": "G3MZM9", "url": "https://omabrowser.org/oma/group/G3MZM9/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "J3QML3-1", "protein_name": "BTB domain containing 35, family member 29", "gene_name": "Btbd35f29", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MGLLVSRVLRCRDSSLLEPQPEAIAGASYIPGSRKRKRNSLEELATSSNVHGPQNQGMYPHQVLNYIYWKRVKISSNDAYQNLFLDGHDSDIKIRALGRTWCLHKVFLCQSGYFANILKGTWRESHQGVINLIIKNEDIDTRSLHFVFGALYTDADLSITPLEVPQVLAAACLLRVDRVIQQCEGIMKETINRNTVCSYYLAAETYRLKAVKTRCFEWLLCNLMVHPSVALYKKVDLKLMYLLALSSDLLVMQKEIDVYTTLKIWMFLYLNPCWNGTMKQLLQHANNWLSTHMAYVDNISFLESEEGLIFQPVFKKLRFQHIIWDLTSTTILEQDRLIPMAWLSPIYKQQWLTLLRTQEYGVIGPQVINEQELEECTMRCGTMIPKDGRYTWKWSVGRLGFPLRVTFTRQCVILRQRCQRCDGSACHNHIRNVIFRITLVCFDSNKRVTFRKTTGYKILTFEYNEEQIVMKLDSDALTFPMCIFCNFLFVNLGNAENK", "length": 498 }, "evidence": [ { "id": "G3MZM9", "url": "https://omabrowser.org/oma/group/G3MZM9/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "J3QMQ9-1", "protein_name": "Predicted gene, 20873", "gene_name": "Gm20873", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MSSLMKKRRRESSSNTLRNIVGRRISHSWKEGNEPVTQWKAIVLDQLPTNPSLYLVKYDGIDSIYGLELYSDDRILNLKVLPPIVVFPQVRDAHLARALVGRAVQHKFEGKDGSEVNWRGVVLAQVPIMKDLFYITYKKDPGLYAYQLLDDYKEGNLHMIPDTPPAEERSGDDSDVLIGNWVEYTRKDGSKKFGKVVYQVLANLSVYFIKFHGDIHIYVYTMVPKILEVEKS", "length": 232 }, "evidence": [ { "id": "G3MZM9", "url": "https://omabrowser.org/oma/group/G3MZM9/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "J3QMS5-1", "protein_name": "BTB domain containing 35, family member 2", "gene_name": "Btbd35f2", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MGLLVSRVLSCRDSSLLEPQPEDIAGASYIPGSRKRKRNSLEELATSSNVHGPQNQGMYPHQVLNYIYWKKVKISSNDAYQNLFLDGHDSDIKIRALGRTWCLHKVFLCQSGYFANILKGTWRESHHGVINLIIKNEDIDTRSLHFVFGALYTDADLSITPLEVPQVLAAACLLRVDRVIQQCEGIMKETINRNTVCSYYLAAETYRLKAVKTRCFEWLLCNLMVHPSVALYKEVDLKLMYLLALSSDLLVMQKEIDVYTTLKIWMFLYLNPCWNGTMKQLLQHANNWLSTHMAYVDNISFLESEEGLIFQPVFKKLRFQHIICDLTSTTILEQDRLIPMAWLSPIYKQQWLTLLRTQEYGVIGPQVINEQELEECTMRCGTMIPKDGRYTWKWSVGRLGFPLRVTFTRQCVILRQRCQRCDGSACHNHIRNVIFRITLVCFDSNKRVTFRKTTGYKILTFEYKEEQIVMKLDSDVLTFPMCIFCNFLFVNLGNAENK", "length": 498 }, "evidence": [ { "id": "G3MZM9", "url": "https://omabrowser.org/oma/group/G3MZM9/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "J3QMW5-1", "protein_name": "Eukaryotic translation initiation factor 4C", "gene_name": "Eif1ad17", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MPKNKGKGGKNRRRGKNENESEKRELVFKEYGQEYAQVTKMLGCGWLEAMCFDGVRRLCHIRGKLRKKVWINTSDIILIGLRDYQDNKADIILKYSPDEARSLKAYGELPEHAKINEMDTFGAGDDDEIMFDDIGEDDEDIDDI", "length": 144 }, "evidence": [ { "id": "G3MZM9", "url": "https://omabrowser.org/oma/group/G3MZM9/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "J3QMW9-1", "protein_name": "BTB domain containing 35, family member 6", "gene_name": "Btbd35f6", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MGLLVSRVLSCRDSSLLEPQPEAIAGASYIPGSRKRKRNSLEELATSSNVHGPQNQGMYPHQVLNYIYWKRVKISSNDAYQNLFLDGHDSDIKIRALGRTWCLHKVFLCQSGYFANILKGTWRESHHGVINLIIKNEDIDTRSLHFVFGALYRDADLSITPLEVPQVLAAACLLRVDRVIQQCEGIMKETINRNTVCSYYLAAETYRLKAVKTRCFEWLLCNLMVHPSVALYKEVDLKLMYLLALSSDLLVMQKEIDVYTTLKIWMFLYLNPCWNGTMKQLLQHANNWLSTHMAYVDNISFLESEEGLIFQPVFKKLRFQHIICDLTSTTILEQDRLIPMAWLSPIYKQQWLTLLQTQEYGVIGPQVINEQELEECTMRCGTMIPKDGRYTWKWSVGRLGFPLRVTFTRQCVILRQRCQRCDGSACHNHIRNVIFRITLVCFDSNKRVTFRKTTGYKILTFEYKEEQIVMKLDSDVLTFPMCIFCNFLFVNLGNAENK", "length": 498 }, "evidence": [ { "id": "G3MZM9", "url": "https://omabrowser.org/oma/group/G3MZM9/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "J3QN64-1", "protein_name": "BTB domain containing 35, family member 22", "gene_name": "Btbd35f22", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MGLLVSRVLRCRDSSLLEPQPEAIAGASYIPGSRKRKRNSLEELATSSNVHGPQNQGMYPHQVLNYIYWKRVKISSNDAYQNLFLDGHDSDIKIRALGRTWCLHKVFLCQSGYFANILKGTWRESHHGVINLIIKNEDIDTRSLHFVFGALYTDADLSITPLEVPQVLAAACLLRVDRVIQQCEGIMKETINRNTVCSYYLAAETYRLKAVKTRCFEWLLCNLMVHPSVALYKEVDMKLMYLLALSSDLLVMQKEIDVYTTLKIWMFLYLNPCWNGTMKQLLQHANNWLSTHMAYIDNISFLESEEGLIFQPVFKKLRFQHIIWDLTSTTILEQDRLIPMAWLSPIYKQQWLTLLRTQEYGVIGPQVINEQELEECTMRCGTMIPKDGRYTWKWSVGRLGFPLRVTFTRQCVILRQRCQRCDGSACHNHIRNVIFRITLVCFDSNKRVTFRKTTGYKILTFEYNEEQIVMKLDSDVLTFPMCIFCNFLFVNLGNAENK", "length": 498 }, "evidence": [ { "id": "G3MZM9", "url": "https://omabrowser.org/oma/group/G3MZM9/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "J3QNQ5-1", "protein_name": "BTB domain containing 35, family member 24", "gene_name": "Btbd35f24", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MGLLVSRVLRCRDSSLLEPQPEGIAGASYIPGSRKRKRNSLEELATSSNVHGPQNQGMYPHQVLNYIYWKRVKISSNDAYQNLFLDGHDSDIKIRALGRTWCLHKVFLCQSGYFANILKDTWRESHHGVINLIIKNEDIDTRSLHFVFGALYTDADLSITPLEVPQVLAAACLLRVDRVIQQCEGIMKETINRNTVCSYYLAAETYRLKAVKTRCFEWLLCNLMVHPSVALYKEVDLKLMYLLALSSDLLVMQKEIDVYTTLKIWMFLYLNPCWNGTMKQLLQHANNWLSTHMAYVDNISFLESEEGLIFQPVFKKLRFQHIIYDLTSTTILEQDRLIPMAWLSPIYKQQWLTLLRTQEYGVIGPQVINEQELEECTMRCGTMIPKDGRYTWKWSVGRLGFPLRVTFTRQCVILRQRCQRCDGSACHNHIRNVIFRITLVCFDSNKRVTFRKTTGYKILTFEYKEEQIVMKLDSDVLTFPMCIFCNFLFVNLGNAENK", "length": 498 }, "evidence": [ { "id": "G3MZM9", "url": "https://omabrowser.org/oma/group/G3MZM9/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "J3QP08-1", "protein_name": "Histone H2A", "gene_name": "H2al1k", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MAKKMQRRRRQKRTRSQRGELPLSLVDRFLREEFHSSRLSSSALSFLTSVLEYLTSNILELAGEVAHTTGRKRIAPEDVRLVVQNNEQLRQLFKPGGTSVNEDDN", "length": 105 }, "evidence": [ { "id": "G3MZM9", "url": "https://omabrowser.org/oma/group/G3MZM9/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "J3QP87-1", "protein_name": "Eukaryotic translation initiation factor 4C", "gene_name": "Eif1ad14", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MPKNKGKGGKNRRRGKNENESEKRELVFKEYGQEYAQVTKMLGCGRLEAMCFDGVRRLCNIRGKLRKKVWINTSDIILIGLRDYQDNKADVILKYNQDEARSLKAYGELPEHAKINETDTFGAGDDDEIVFDDIGDEDEDIDDI", "length": 144 }, "evidence": [ { "id": "G3MZM9", "url": "https://omabrowser.org/oma/group/G3MZM9/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "J3QP96-1", "protein_name": "PRAME like 3C", "gene_name": "Pramel3b", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MMDTKDPPTLLDLATQSLLSNEHAAIQALEEIPRELFVPLFTAAFTGRHKNILTAIVKAWPFACLHIGALSVQEPERELLKALIESLQFLPALNSATRSPKLRILDLRQDAGCKTVCPDISTNSTICFRSCAHSEHSIFKIEGQESLSSSKSEAQPSRLPMELIVDISLDGTLRERNFFALLQNKVEQSLGSLHLCCRDLQINNLCECRHALSHLDLKCVDHLAVDESPLTEVTKLLSHTIQLDSLSLSKIACRSLNGRTFRNFITQLSRMNHLKELSLSSFCLTDHLETVLRVLSADLEFLYLPFCGLSYSDFKFLSECSQVSHLKLLNVNNNPIYWEDCEPFYYLLQNVSSTLQHLKICYCFLTDSTISVLIPALTRCSQLRVLHFYSNQITMGMLMRILELLTPLKELKHVIYPIPVHCYGRWHFQGSLDRQKVEDVQRQLNLMLQEAERSDMNWITYSD", "length": 463 }, "evidence": [ { "id": "G3MZM9", "url": "https://omabrowser.org/oma/group/G3MZM9/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "J3QPI8-1", "protein_name": "Eukaryotic translation initiation factor 4C", "gene_name": "Eif1ad16", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MPKNKGKGGKNRRRGKNENESEKRELVFKEYGQEYAQVTKMLGCGWLEAMCFDGVRRLCHIRGKLTKKVWINTSDIILIGLRDYQDNKADVILKYNPDEARSLKAYGELPEHAKINEMDTFGAGDDDQIVFDDIGEDDEDIDDI", "length": 144 }, "evidence": [ { "id": "G3MZM9", "url": "https://omabrowser.org/oma/group/G3MZM9/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "J3QQ02-1", "protein_name": "Eukaryotic translation initiation factor 4C", "gene_name": "Eif1ad11", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MPKNKGKGGKNRRRGKNENESEKRELVFKEYGQEYAQVTKMLGCGRLESMCFDGVRRLCHIRGKLRKKVWINTSDIILIGLRDYQDNKADVILKYNPDEARSLKAYGELPEHAKINEMDTFGPGDDDEIVFDDIGDDDEDIDDI", "length": 144 }, "evidence": [ { "id": "G3MZM9", "url": "https://omabrowser.org/oma/group/G3MZM9/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "K7GP63-1", "protein_name": "Large ribosomal subunit protein eL39", "gene_name": "RPL39", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MSSHKTFRIKRFLAKKQKQNRPIPQWIRMKTGNKIRYNSKRRHWRRTKLGL", "length": 51 }, "evidence": [ { "id": "G3MZM9", "url": "https://omabrowser.org/oma/group/G3MZM9/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "K7N5V5-1", "protein_name": "Predicted gene 5862", "gene_name": "Gm5862", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MALFARLCRLFQRVNVDGRETREGRKDADLPSERNEGRRRWTWRMCMAHRQTTSPVPVKSKKQFEKEEKELIKKIQLTTEETNELRDRLIYVTEGSMNKRPYHRQTRHYKELKLKEKEIMTYLHDLEMKNMEARENNQELKKEKNFYRNLHTRILLEENLIKKKLVILQQESKEVHADWATIHQSLVELNLSGKDEQEKTSNLETQEHQVSEAARELGLATAEEDSILQNELPCQEAPAEHHPQHPPSSSDESSSDESSYSTCPEWE", "length": 267 }, "evidence": [ { "id": "G3MZM9", "url": "https://omabrowser.org/oma/group/G3MZM9/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "K7N660-1", "protein_name": "Predicted gene 10220", "gene_name": "Gm10220", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MALFARLCRLFQRVNVDGRETREGRKDADLPSERNEGRRRWTWRMCMAHRQTTSPVPVKSKKQFEKEEKELIKKIQLTTEETNELRDRLIYVTEGSMNKRPYHRQTRHYKELKLKEKEIMTYLHDLEMKNMEARENNQELKKEKNFYRNLHTRILLGENLIKKKLAILQQESKEIHADWAIIQQRLVELNLSGKDEQEKTSNLEAQENQVSEAARKLGLATAEEDSILQNELPCQEAPAEHHPQHPPSSSDESSSDESSYSTCPSWE", "length": 267 }, "evidence": [ { "id": "G3MZM9", "url": "https://omabrowser.org/oma/group/G3MZM9/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "K7N6B6-1", "protein_name": "Vomeronasal type-1 receptor", "gene_name": "Vmn1r168", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MSSQNGAMKTTEEVALQIVLLCQFGIGTMANILLFVHNFSPLLTGCQLRPKEVICANMAVSSILILFMTVFPNNVFVAQRNLLNDLQCKLEYFVYMVARSTNLCSTCVLSTYQFVTLVPGNFSELMVRGRSPKVISYSCCSCWLFGILYNVYIPMKVSGPQNRHNKTSTKSKWVCFTSGFSVGIVFLSFAHDAIFISIMVWASVSMVRLLYRHYQRLQYIFPPHQGNRGYAEIRAAHSIVLLVVTFVSFYLLHCICFILHIVFVDSNLWLRHIGEVLTSSFPTISPLLLIFRDPSYPCSLIFNYKKPVI", "length": 309 }, "evidence": [ { "id": "G3MZM9", "url": "https://omabrowser.org/oma/group/G3MZM9/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "K7N6B7-1", "protein_name": "Vomeronasal type-1 receptor", "gene_name": "Gm10670", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MSVRGKSLKTTEEVALQIILLCQFGVGTMANDFLFVHNFSPVLTGSKQRPRQVILSHMAVANALTLFLTVFPNNMMAFAPRNPPTELKCKLKFFSHLVTRSTNLCSTCVLSMHQFVTLVPISRGKLLLRASVPNLVSYSCYGCWFFSVLSNIHIPIKVTGPQITDNNTDSKSKFFCSTSGFTVRIVFLQFSHDATFMSIMVWTSVSMVLLLHRHRQRMQHILTPNQNPRGQAESRATNTILMLVVTFVSFYLLNFICIIFHTFFIHYNLFIRLLGEILAAGFPTISPLLLIFRDPKNPCLELFHCFKPESLQNLKHRRQLH", "length": 321 }, "evidence": [ { "id": "G3MZM9", "url": "https://omabrowser.org/oma/group/G3MZM9/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "K7N6G6-1", "protein_name": "Predicted gene 16440", "gene_name": "Gm16440", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MFSWLRRLCQKENGDEGEIRTTEKEEGILSHEKGRRKSFWRRHRSARNTSTQNSKITKQRSKINELEELKLDMRKISNDMEEMGGILELYIYEDLNYRMNTEFNIIKSQHEKTMLDMNEMIQSIIGSMQYSKELIEDNYSYSIKEDHLLRECTQLSEKVRILLNENRKLLVEQAGTQLSHEEEKRFCEEASKNICASSAKEQQCVNSSRNRNMAQTTT", "length": 218 }, "evidence": [ { "id": "G3MZM9", "url": "https://omabrowser.org/oma/group/G3MZM9/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "K7N6J5-1", "protein_name": "Vomeronasal type-1 receptor", "gene_name": "Vmn1r127", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MSDHGKSVKTTEEVALQLLLLCQFGVGTLANVFLFVHNFSPVLTGSKQRPRQVILSHMAMANALTLFLTIFPNNMIAFAPKTPPTELKCKLEFFSHMVARSTNLCSTCVLSIHQFVTLVLVNRGKLILRASVPNFVSYSCYSCWFFSVLSNIHIPIKVTGPQITDNNTDSKSNLFCSTSGFIVGIVFLQFAYDATFMSIMVWTSVSMILLLHRHRQRMQHILTPNQNPRGQAETRATRTILMLVVTFVSFYLLNFICIIFHTLLMHSHLFIRLVSEVLTAVFPSICPLLLIFRDPKDPCSVLFNC", "length": 305 }, "evidence": [ { "id": "G3MZM9", "url": "https://omabrowser.org/oma/group/G3MZM9/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "K7N6P1-1", "protein_name": "Reproductive homeobox 2H", "gene_name": "Rhox2h", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MEKRSINYLLDVGPEEDEENANGVKTLMVLLAGEGRNEGESGRGLPGSGVSAAEGYRAGELSAGGPAAPVAGLMDNSNQEDLSATGCAQEKETQPEEPVPDSMGDLENVKPMSGPWSTVNPVRVLVPKFRHLWRHNFNVLQLQELESIFQCNHYISTTEENRLARSMGVSEATVQEWFLKRREKYRSYKRL", "length": 191 }, "evidence": [ { "id": "G3MZM9", "url": "https://omabrowser.org/oma/group/G3MZM9/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "K7N6T9-1", "protein_name": "Vomeronasal type-1 receptor", "gene_name": "Vmn1r175", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MLLQNKSVKTTEEVALQVLLLCQVGFGTAVNIFLIVHNLSPILNGSQQRPIKVILANLAVGNTLILLFAFPNNMTLFVPKDPPTDLKCKLGYFIWLVARSTNMCSTCFLSTYQLVTLAPGTWGRVMLRGRAPKFVRYICYSCWLFSVLNNAHIPMKVNGPQKTHNDTNTKNKWVCSTTGFSIGMRILSFAHDAVFISIIIWSSVSMVILLNRHHQRLQHIQSTNQKLRVHAETRASHTILLLVVTFVTCYLLDCICTVCNISFLDSRVWLRRVKQILDVSFPTFSPLLLIFRDPKDPCSLLFCC", "length": 304 }, "evidence": [ { "id": "G3MZM9", "url": "https://omabrowser.org/oma/group/G3MZM9/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "K7N6U2-1", "protein_name": "Predicted gene 3542", "gene_name": "Gm3542", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MFSRLLRLCQKENGDEGETRPKKKEEGILSHEKGRRKSFWRRHRSARNTSTQNSNITNQISNINKVEELKLHIRKTSNERKEMCGILNVYMYEDLNYRMNTEFNIIKSQHEKTMLDMNKMIQSIIGSMQYSKELIEDNYSYSIKEDHLLRECTQLNEKVRILLNENRKLLVEQAGTQVSCEEERGSLRRPARTSVPQVQRNSSFPKCETVQQKLEHGTDHDMISLKEKCWWKRTGCAQEIHHCCLSSLITMAVMGCMLLLYFGFLGMNRP", "length": 270 }, "evidence": [ { "id": "G3MZM9", "url": "https://omabrowser.org/oma/group/G3MZM9/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "K7N6W5-1", "protein_name": "Predicted gene 17019", "gene_name": "Gm17019", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MALFARLCRLFQRANVDGRDTREGRKDADLPSERNEGRRRWTWRMWMALRQTSSPVPVISKKQFEKEEKKLIKEIQLTTEETNELRDRLIYVTEGSMNKRPYHRQNPLYEKLKLKEKEIMTFLHNLEMENMEAQENKQELKKETHFYRNLHSRLLMEENLIKKKSMTLQQESKEVQADWAIIHQRLVELNLSVKDEQENSNLETPEYQVSEAARELGLATAEEDSILQNELPGQEAPAEHHLQHPQSSSDESSSI", "length": 255 }, "evidence": [ { "id": "G3MZM9", "url": "https://omabrowser.org/oma/group/G3MZM9/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "K7N6W9-1", "protein_name": "Vomeronasal type-1 receptor", "gene_name": "Vmn1r170", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MLLQNKSVKTTEEVALQVLLLCQVGVGTAVNIFLIVHNLSPNLNGSQQRPIKVILANLAVGNTLILLFAFPNNMTLFVPKDPPTDLKCKLGYFIWLVARSTNMCSTCSLSTYQLVTLAPGTWGRVMLRGRAPKFVRYICYSCWLFSVLNNAHIPMKVSGPQKTHNDTNTKNKWVCSTTGFSIGMRILSFAHDAVFISIIIWSSVSMVILLNRHHHRLQHIQSTNQKLRVHAESRASHTILMLVVTFVTCYHLDCICTFCNISFLDSQLWLRRVKQILDASFPTFSPLLLIFRDPKDPCSLLFCC", "length": 304 }, "evidence": [ { "id": "G3MZM9", "url": "https://omabrowser.org/oma/group/G3MZM9/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "K7N6X3-1", "protein_name": "Vomeronasal type-1 receptor", "gene_name": "Vmn1r94", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MSDHGKSVKTTEEVALQLLLLCQFGVGTLANVFLFVHNFSPVLTGSKQRPRQVILSHMAMANALTLFLTIFPNNMIAFAPKTPPTELKCKLEFFSHMVARSTNLCSTCVLSIHQFVTLVLVNRGKLILRASVPKFVSYSCYSCWFFSVLSNIHIPIKVTGPQITDNNTDSKSNLFCSTSGFIVGIVFLQFAYDATFMSIMVWTSVSMVLLLHRHRQRMQHILTPNQDARGQAETRATHTILMLVVIFVSFYLLNFICIIFHTLLMHSHLFIRLVSEVLAAVFPSICPLLLIFRDPKDPCSVLFNC", "length": 305 }, "evidence": [ { "id": "G3MZM9", "url": "https://omabrowser.org/oma/group/G3MZM9/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "K7N6X7-1", "protein_name": "Vomeronasal type-1 receptor", "gene_name": "Vmn1r103", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MSDHGKSVKTTEEVALQLLLLCQFGVGTLANVFLFVHNFYPVLTGSKQRPRQVILSHMAVANALTLFLTIFPNNMIAFAPKTPPTELKCKLEFFSHMVARSTNLCSTCVLSIYQFVTLVLVNRGKLILRASVPNFVSYSCYSCWFFSVLSNIHISIKVTGPQITDNNTDSKSNLFCSTSGFIVGIVSLQFAYDATFMSIMVWTSVSMVLLLHRHRQRMQHILTPNQYRRGQAETRATRTILMLVVTFVSFYLLNFICIIFHTLLMHSHLFIRLVSEVLAAVFPSISPLLLIFRGPKDPCSVLFNC", "length": 305 }, "evidence": [ { "id": "G3MZM9", "url": "https://omabrowser.org/oma/group/G3MZM9/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "K7N6Y3-1", "protein_name": "Vomeronasal type-1 receptor", "gene_name": "Vmn1r115", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MSDHGKSVKTTEEVALQLLLLCQFGVGTLANVFLFVHNFSPVLTGSKQRPRQVILSHMAMANALTLFLTIFPNNMIAFAPKTPPTELKCKLEFFSHMVARSTNLCSTCVLSIHQFVTLVLVNRGKLILRASVPKFVSYSCYSCWFFSVLSNIHIPIKVTGPQITDNNTDSKSNLFCSTSGFIVGIVFLQFAYDATFMSIMVWTSVSIILLLHRHRQRMQHILTPNQNPRGQAETRATRTILMLVVTFVSFYLLNCICIIFHAFYIHSRLFIRLVSEVLAAVFPSICLHNGVLLSY", "length": 295 }, "evidence": [ { "id": "G3MZM9", "url": "https://omabrowser.org/oma/group/G3MZM9/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "K7N6Z0-1", "protein_name": "Predicted gene 17026", "gene_name": "Gm17026", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "XRSSWVPKQACCPCSSGYFRERIEYTQTPDQGRRRPAAHHGGKGQETTGHGEGSAGAASPQAPTINDQEKRHERLEKLKRELQNIKNARDELQGILANYTNKDLNDRINFETFMLQMQHDQVMTDLKRMPQDISEALYKCKQLTKENQFYCFRNCHLLIESNLIQHKVRMLRKENRQLLREQIALEECNIETKILCKEGSQKIKDHYTKQQQI", "length": 213 }, "evidence": [ { "id": "G3MZM9", "url": "https://omabrowser.org/oma/group/G3MZM9/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "K7N701-1", "protein_name": "Vomeronasal type-1 receptor", "gene_name": "Vmn1r159", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MSDHGKSVKTTEEVALQLLLLCQFGVGTLANVFLFVHNFYPVLTGSKQRPRQVILSHMSVANALTLFLTIFPNNMIAFAPKTPPTELKCKLEFFSHMVARSTNLCSTCVLSIHQFVTLVLVNRGKLILRASVPNLVSYSCYGCWFFSVLSNIHIPIKVTGPQITDNNTDSKSNLFCSTSGFIVGIVFLQFAYDATFMSIMVWTSVSMVLLLHRHRQRMQHILTPNQNTRGQAESKATRTILMLVFTFVSFYLLNFICIIFHTLLMHSHFFIRLVSEVLAAVFPSISPFLLIFRDPKDPCSVLFNC", "length": 305 }, "evidence": [ { "id": "G3MZM9", "url": "https://omabrowser.org/oma/group/G3MZM9/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "K7N708-1", "protein_name": "Predicted gene 10128", "gene_name": "Gm10340", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MFSWLLRLFQKENGDEGETRPTEKEEGILSHEKGRRKWLWRRHRSARNTSTQNSKMTKKRSKRNELEELKLDMRKISNDMEEMCGILNLYMYEDLNYRMNTEFNIIKSQHEKTMLDMNKMIQSIIGSMQYSKELIEDNYSYSIKEDHLLRECTQLHENVRILLNENRRLLVEQAGHKCPVGKKRGSLRRPARTSVSQVPRNTSVI", "length": 205 }, "evidence": [ { "id": "G3MZM9", "url": "https://omabrowser.org/oma/group/G3MZM9/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "K7N731-1", "protein_name": "Vomeronasal type-1 receptor", "gene_name": "Vmn1r57", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MEVLALNILLLCHVVVGTVGNILLFVHNFSPNLTDSRLRPIQVILINLAVANAFMLLFSTYSYDLIDFVPRKPPTDLKCKLAYFFHMVARGTIMCSTCVLSTYQFVTLVPGNWARVMFREISPKVVSYSCFSCWLFSVLNNAYIPMNVSGPQKSHNDSDSKDNWICSISGVSVDMNFLRFSHDIIFLGIMAWTSVSMVIHLNRHHQRMNHIHKVNQNNRGHAETRAAHTILMLVVTFVSLYILNCIIILFHITFVESRLSLRHVTKLLSLSFPTISPLLLIFREPRGHCSLLFSVGLEIHVTGGVITEEQ", "length": 310 }, "evidence": [ { "id": "G3MZM9", "url": "https://omabrowser.org/oma/group/G3MZM9/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "K7N744-1", "protein_name": "Predicted gene 8104", "gene_name": "Gm8104", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MFSWLRRLFHRENGNQGETRPRQKESAIPSCKNRRMKSFWGRHMSAGKTSSQNCNITNHMKNMNKLDDMKFYIRKINAERLELFRILDIDMNTDLNYRMNIDFTIIKSQHEKTMLDMEKMTQSISDTIEKYKEFIEDKDSYSFTHTYLLKECNQLKEKVRMLLNENRKLLVEQADQETSYGEEKRFCDETSKNIHPKC", "length": 198 }, "evidence": [ { "id": "G3MZM9", "url": "https://omabrowser.org/oma/group/G3MZM9/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "K7N751-1", "protein_name": "Predicted gene 3696", "gene_name": "Gm3696", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MFSWLLRLFQKENGDEGETRPKKKEEGILSHEKGRRKWLWRRHRSARNTSTQNSKMTKKRSKRNELEELKLDMRKISNDMEEMCGILNLYMYEDLNYRMNTEFNIIKSQHEKTMLDMNKMIQSIIGSMQYSKELIEDNYSYSIKEDHLLRECTQLNENVRILLNENRRLLVEQAGHKCPVGKKRGSLRRPQEHLCPKCQGTAV", "length": 203 }, "evidence": [ { "id": "G3MZM9", "url": "https://omabrowser.org/oma/group/G3MZM9/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "K7N757-1", "protein_name": "Predicted gene 3667", "gene_name": "Gm3667", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MFSWLLRLFQKENGDEGETRPTEKEEGILSHEKGRRKSFWRRHRSARNTSTQNSKMTKKRSKINELEELKLDMRKISNDMEEMCGILNLYMYEDLNYRMNTEFNIIKSQHEKTMLDMNKMIQSIIGSMQYSKELIEDNYSYSIKEDHLLRECTQLNEKVRILLNENRRLLVEQAGHKCPVGKKRGSLRKPARTSVSQVPRNSSVK", "length": 205 }, "evidence": [ { "id": "G3MZM9", "url": "https://omabrowser.org/oma/group/G3MZM9/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "K9J7F4-1", "protein_name": "Vomeronasal type-1 receptor", "gene_name": "Vmn1r260", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MSAHGNSLKTTEEVALQILLLCQFGVGTVANVFLFVHNFSPVLTGSKQRPRQVILSHMAVANALTLFLTIFPNNMMAFAPKTPPTELKCKLESFSHLVVRSTNLCSTCVLSVHQFVTLVPLNRGKGKLVLRASVTNMASYSSCSCWFFSVLSNIHIPIKFSGPQITDNNTDSKRKLFCSTSGFSVGIVFLQFAYDATFMSIMVWTSVSMVLLLRRHRQRMQHILTPNQNPRGQAESKATHTILMLVFTFVSFYLLNCICIIVHALFMHSHFFVRLVSEILTAIFPSISPLLLIFRDPKDPCSVLFNC", "length": 307 }, "evidence": [ { "id": "G3MZM9", "url": "https://omabrowser.org/oma/group/G3MZM9/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "K9J7G0-1", "protein_name": "Vomeronasal type-1 receptor", "gene_name": "Vmn1r163", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MSAHGKSVKTTEEVALQILLLCQFGVGTVANVFLFVHNFSPVMTGSKKRPRQVILSHMAVANALTLFLTIFPNNMSAFAPKTPPTELKCKLEFFSHMVARSKNLCSTCVLSIHQFVTLVPVNRGKGKLILRASVPNLWNYSCYSCWFYSVLSNIHIPIKVTGPQITDNNTDSKSNLFCSTSGFIVGMVFLKFSHDATFMTIMVWTSVSMVLLLHRHHQRMQHILTPNQDARGQAETRATHTILMLVVTFVSFYLLNCICIIFHAFSIHSRLFIRLVSEVLAAVFPNICPLLLIFRDPKDPCSVLFKC", "length": 307 }, "evidence": [ { "id": "G3MZM9", "url": "https://omabrowser.org/oma/group/G3MZM9/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "K9J7G4-1", "protein_name": "Vomeronasal type-1 receptor", "gene_name": "Vmn1r242", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MSVHDKSVKTTEEVALQLLLLCQFGVGTVANVFLFVHNFSPVLTGSKQRPRQVILSHMAVANALTLFLTIFPNNMMAFAPKTPPNELKCKLESFSRLVARSTNLCSTCVLSIHQFVTLFPVSRGKGKLILRASVQNLASYSCYSCWFFSVLSNIHIPIRVTGPQITDNNTDSKSNLFCSTSGFIVGIVLQFAHDATFMSIMIWTSVSMILLLHRHCQRMQDILTPNQNPRGQAETRATRTILMLVVTFVSFYLLNCICIIFHAFFIHSRLFIRLVSEVLAAVFPSICPLLLIFRDPKDPCSLLFKC", "length": 306 }, "evidence": [ { "id": "G3MZM9", "url": "https://omabrowser.org/oma/group/G3MZM9/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "K9J7H2-1", "protein_name": "Vomeronasal type-1 receptor", "gene_name": "Vmn1r256", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MSAHGKSLKTTEEVALQLLLLCQFGVGTVANVFLFVHNFSPVLTGSKQRPRQVILGHMAVANALTLFLTIFPNNMMAFAPKTPPNELKCKLESFSLLVARSTNLCSTCVLSIHQFFTLFPVSRGKGKLILRASVQNLASYSFYSCWFFSVLSNIHIPIRVTGPQITDNNTDSKSNLFCSTSGFIVGIVLQFAHDDTFMSIMVWTSVSMVLLLHRHRQRMQHILTPNQNPRGQAESRATHTILMLVFTFVSFYLLNCICIIFHAFSIHSCLFIRLVSEVLAAVFPSICPLLLIFRDPKDPCSVLFKC", "length": 306 }, "evidence": [ { "id": "G3MZM9", "url": "https://omabrowser.org/oma/group/G3MZM9/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "K9JA28-1", "protein_name": "Interferon lambda receptor 1", "gene_name": "IFNLR1", "tax_id": 9031, "organism": "Gallus gallus", "sequence": { "sequence": "MSAWRIRVLATLCFLWQPRVHGQLPPPQNVTLLSKDFDMILTWTPGEGSPPDVLYTVRYESKTRMDKWIKVPHCRNIHSVSCNLTCVIPNFFIKFRAQVKATSGRFHSPWVKSQFKEYHLDVELAPPLLNVNVKENVIHVNATFPMAICVESLPWMYDFNLWEAGSEDKKQYKSIFRKKAVTIDTTALRGNYCFNARSSIQSIDFKHSKFSQPVCMQLNYEGEWKFPFSATIPVFVLLILLTSASIIWLLKQDAKHKKMPQTLDLSNCKIAGPTFCCELRENEFLTDCLICTDKPMSQGKKNKTLAQNNQMWMASFLPSSSSEEEEEEEEEDSSSFIPYTEMLQFPRKHFNFQTPRTADAETILDSTSGVLSVVGGSTLDLSALGFSFFPIRKNEMDTSGSQGNEKASHSHSSSLGRISLTDVRFPGPREHGQHGTDSNDCLEVSLLHTLMNSSCTRLPADEHCLYKKDHDFTICYQKPTLDQPVQVSENPLLNEDPSMEKFIYLQTLQVAEDEGFASDCDSGNFTEGTPPASTVLSDELRISDMEKRYDKKFKFKGYQHSHYMRRS", "length": 567 }, "evidence": [ { "id": "G3MZM9", "url": "https://omabrowser.org/oma/group/G3MZM9/", "database": "OMA" } ], "glygen_name": "Chicken", "common_name": "Chicken" }, { "uniprot_canonical_ac": "L7MU37-1", "protein_name": "Reproductive homeobox 3H", "gene_name": "Rhox3h", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MSMKPERSISNWIHSNVEPAGRNLFQVNGHRSALLPELPQDYHRASRSVNGCETKMDSTQGTKVLPAEESRNEEDGGQVESALGATAARGRGKEALNGESPAAAGTAGLVEEDRNKEDGGTKGGEKNEQEVREQIPEHVEGESDQAEAPRQVPRRRLHHRFTQWQLDELERIFRMNYFLSLEARKQLARWMGVNEAIVKRWFQKRREQYRWYKRL", "length": 215 }, "evidence": [ { "id": "G3MZM9", "url": "https://omabrowser.org/oma/group/G3MZM9/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "L7MU51-1", "protein_name": "Olfactory receptor", "gene_name": "Or4a76", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MGQSNNVTEFVLLGFTQDPAGQKALSVMFSLIYIVTMVGNLLIVGTVIASPSLGSPMYFFLASLSLMDAIYSTAITPKLIVDLLCEKKTISFRACISQLFIDHLFGGVDIVILLAMAYDRYVAICKPLHYLIIMNRRVCILFLVMAWAGGLAHALFQVLAVYNFPFCGPNIIDHFGCDIYPLLLLACTDTYFLGLSIIGNNGAMCIVIFTLLLLSYGIILRFLKNHSQEGRRKALSTCGSHITVVFLFFVPCIFMYVRPVSSFPIDKFITVIYTIVTPMLNPLIYTLRNSEMKNSMEKLLQKTLSPSRIRLSSCCLCY", "length": 318 }, "evidence": [ { "id": "G3MZM9", "url": "https://omabrowser.org/oma/group/G3MZM9/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "L7MU81-1", "protein_name": "BTB domain containing 35, family member 17", "gene_name": "Btbd35f17", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MGLLVSRVLRCRDSSLLEPQPEAIAGASYIPGSRKRKRNSLEELATSSNVHGPQNQGMYPHQVLNYIYWKRVKISSNDAYQNLFLDGHDSDIKIRALGKTWCLHKVFLCQSGYFANILKGTWRESHHGVINLIIKNEDIDTRSLHFVFGALYTDADLSITPLEVPQVLAAACLLRVDRVIQQCEGIMKETINRNTVCSYYLAAETYRLKAVKTRCFEWLLCNLMVHPSVALYKEVDLKLMYLLALSSDLLVMQKEIDVYTTLKIWMFLYLNPCWNGTMKQLLQHANTWLSTHMAYVDNISFLESEEGLIFQPVFKKLRFQHIICDLTSTTILEQDRLIPMAWLSPIYKQQWLTLLRTQEYGVIGPQVINEQELEECTMRCGTMIPKDGRYTWKWSVGRLGFPLRVTFTRQCVILRQRCQRCDGSACHNHIRNVIFRITLVCFDSNKRVTFRKTTGYKILTFEYKEEQIVMKLDSDVLTFPMCIFCNFLFVNLGNAENK", "length": 498 }, "evidence": [ { "id": "G3MZM9", "url": "https://omabrowser.org/oma/group/G3MZM9/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "L7MU83-1", "protein_name": "BTB domain containing 35, family member 18", "gene_name": "Btbd35f18", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MGLLVSRVLRCRDSSLLEPQPEAIAGASYIPGSRKRKRNSLEELATSSNVHGPQNQGMYPHQVLNYIYWKRVKISSNDAYQNLFLDGHDSDIKIRALGKTWCLHKVFLCQSGYFANILKGTWRESHHGVINLIIKNEDIDTRSLHFVFGALYTDADLSITPLEVPQVLAAACLLRVDQVIQQCEGIMKETINRNTVCSYYLAAETYRLKAVKTRCFEWLLCNLMVHPSVALYKEVDLKLMYLLALSSDLLVMQKEIDVYTTLKIWMFLYLNPCWNGTMKQLLQHANNWLSTHMAYVDNISFLESEEGLIFQPVFKKLRFQHIICDLTSTTILEQDRLIPMAWLSPIYKQQWLTLLRTQEYGVIGPQVINEQELEECTMRCGTMIPKDGRYTWKWSVGRLGFPLRVTFTRQCVILRQRCQRCDGSACHNHIRNVIFRITLVCFDSNKRVTFRKTTGYKILTFEYKEEQIVMKLDSDVLTFPMCIFCNFLFVNLGNAENK", "length": 498 }, "evidence": [ { "id": "G3MZM9", "url": "https://omabrowser.org/oma/group/G3MZM9/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "L7MUB9-1", "protein_name": "Reproductive homeobox 2G", "gene_name": "Rhox2g", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MERQSINYKLDVGPEEDEENANGIKTLMVLLAGEGRNEGESGRGLPGSGVSAAEGYRAGELSAGGLAAPVADLMDNNNQEDLGATGCAQEKEKQPEEPVPDSMGDLENVKPMSGPWSTVNPVRVLVPEFLHGWQQSFNVLQLQELESIFQCNHYISTTEAKCLARSMGVSKATVQEWFLKRREKYRSYKRL", "length": 191 }, "evidence": [ { "id": "G3MZM9", "url": "https://omabrowser.org/oma/group/G3MZM9/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "L7N1X6-1", "protein_name": "F-box/WD repeat-containing protein 15", "gene_name": "Fbxw15", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MAIHLPCLPMMKILSYLDAYSLLQAAQVNKDWNELASSDVLWRKLCQKRWLYCDMDTLQLQGKETWKQFFIDRIWQERAKFRAKAKDFTYKEIPLMCGLFGYACYISGCGLTRKGQDKSVVCMVNSKNTISTWDVHKSVITWKSPEQPASIKLLTTLPEMHIAVTVDIQSTIKLWDCHNREALATNNLKSPCKSLKAVFTKDGPIVLIGDTLGNIHIFRIPDLYLISTVNVLPYGFDGIYCSPQKKWVLLSKKHPHILPKVFYMSSFLRTSEFSAPVSTVLKLSLYERVFWTPRREDRITLMSRSGFPQVKMFETYDIKLEEFGNKRIVKGKLIASFELQCHKVNPQRFGVSDKNVIVCSTESSLLLFDINGLRLKTFQYCPEMIVKLSVDPLHVIVICNTGSMDVYAWEERSLLLRKCYRLHIERPLPLYGFIYKAACDDVSIIQLITDELSLSSLTSYALNICS", "length": 466 }, "evidence": [ { "id": "G3MZM9", "url": "https://omabrowser.org/oma/group/G3MZM9/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "L7N1X9-1", "protein_name": "Demilune cell and parotid protein 1", "gene_name": "Dcpp1", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MFQLEAMLALLILAFLGTPTVLTQDYHGPEVGKHSCTSAPEGKNITSIRVFLKGRLIVGIQLNYDDNKDGQVYGSTAGKEMVARLSKEEHIIAAQGTYTPSALTQIIFTTNQPRQLMVGYYVGNSEYSSFPNDPSHVLKGACVSWRAGGIKSILFLWGSENSSCVKYGHSG", "length": 171 }, "evidence": [ { "id": "G3MZM9", "url": "https://omabrowser.org/oma/group/G3MZM9/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "L7N1Y3-1", "protein_name": "PRAME like 51", "gene_name": "Pramel51", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MIHSKERKYRLGLLEPGVTAFPCPNMVICLHCPDQDDSLEEVTEECYSPPTLQNLAIQSLLRDEALAISALTDLPQSLFPVIFEEAFTDGHIGILKAMIPVWPFPYLSLGKQINNCNLETLKAMLEGLDILLAQKVQTSRCKLRVINWREDDLKIWAGSHEGEGLPDFRTEKQPIENSPGCEVKKELKVTTEVLRMKGRLDESTTYLLQWAQQRKDSIHLFCRKLLIEGLTKASVIEIFKTVHADCIQELILRCICIEELAFLNPYLKLMKSLFTLTLDHIIGTFTLGDSEKLDEETIFSLISQLPTLHCLQKLYINDVPFIKGNLKEYLRCLKKPLETLCISNCDLSQSDLDCLPFCLNICELKHLHISDIYLCDLLLEPLGFLLERVGDTLKTLELVSCCIVDFQFSALLPALSQCSHLREVTFYDNDVSLPFLKQLLHHTALLSQLIYECYPAPIECYDDSGVILTHRLESFCPELLDILRAKRQLHSVSFQTTKCSKCGGCYIYDRHTQCCRFVEL", "length": 520 }, "evidence": [ { "id": "G3MZM9", "url": "https://omabrowser.org/oma/group/G3MZM9/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "L7N1Y5-1", "protein_name": "Olfactory receptor", "gene_name": "Or11g25", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MKTLSSPSNSSTITGFILLGFAYPREGQILLFVIFFIVYILILMGNASIICAVYCDQRLHTPMYLLLANFSFMEIGYVTSTVPNMLANFLSDTKVISFSGCFLQFYFFFSFGSTECFFLAVMAFDRYLAICRPLHYSSLMTGRLRNTLVTSCWVLGFLWFPVPIIIISQMSFCGSRIIDHFLCDPGPLLALACSRVPLIEVFWSIIMSMLLVIPFLFIMGTYILVLRAVFRLPSREGQKKAFSTCGSHLTVVSLFYCSVMIMYLSPTSEHEAGMQKLVTLFYSVGTPLLNPMIYSLRNKDMKNALQKILRT", "length": 311 }, "evidence": [ { "id": "G3MZM9", "url": "https://omabrowser.org/oma/group/G3MZM9/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "L7N227-1", "protein_name": "Vomeronasal type-1 receptor", "gene_name": "Vmn1r125", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MSAHGKSMKTTEEVALQIILLCQFGIGTVANVFLFVHNFSPVLTGSKQRPRQVILSHMAVANALTLFLTIFPNNMSAFARKTPPTELKCKLEFFSHMVARSTNLCSTCVLSVHQFVTLVPVNRGKGKLILRASVPNFANYSCYSCWFFSVLSNIHIPIKVTGPQITDNNTDSKSNLFCSTSGFIVGMVFLQFSHDATFMSIMVWTSVSMVLLLHRHRQRMQHILTPNQDARGQAETRATHTILMLVVTFVSFYLLNCICIIFHAFSIHSRLFIRLVSEVLAAVFPSICPLLLIFRDPKDPCSVLFKC", "length": 307 }, "evidence": [ { "id": "G3MZM9", "url": "https://omabrowser.org/oma/group/G3MZM9/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "L7N255-1", "protein_name": "Predicted gene 3099", "gene_name": "Gm3099", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MFSRLLRLCLKGNGDEGETRPKKKEEGILSHEKGRRKLFWRRHRSARNTSTQNSNITNQISNINEVEELKLHIRKISNERKEMCEILNVYMYEDLNYRMNTEFNIIKSQHEKTMLDMNKMTQFIIGSMQYSMELIEDNYSYSIKEDHLLRECTQLNKKVRILLNENRKLLVEQAGTQVSCGEEKRFCEEASKNICASSAKEQQLP", "length": 205 }, "evidence": [ { "id": "G3MZM9", "url": "https://omabrowser.org/oma/group/G3MZM9/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "L7N259-1", "protein_name": "Demilune cell and parotid protein 3", "gene_name": "Dcpp3", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MFQLEAMLALLILAFLGTPTVLTQDYHGPEVGKHSCTSTPEEKNITSIRVFLQARSIVGIQFNYDDKDGQVYGSTAGKEMVARLSKEEHITGVEGSYSPSALTQIVFTTTQPRQLMVGYHVGIYQYSSYPDDPSFVLKGACVSWRAGGIKSILFLWGSENSSCVKYGHSG", "length": 170 }, "evidence": [ { "id": "G3MZM9", "url": "https://omabrowser.org/oma/group/G3MZM9/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "L7N270-1", "protein_name": "Vomeronasal type-1 receptor", "gene_name": "Vmn1r123", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MSAHGKSLKTTEEVALQLLLLCQFGVGTVANVFLFVHNFSPVLTGSKQRPRQVILIHMAVANALTLFLTIFPNNMSAFAPKTPPTELKCKLEFFSHMVARSTNLCSTCVLSIHQFVTLVPVNRGKGKLILRASIPNLWNYSCYNCWFYSVLSNIHIPIKVTGPQITDNNTDSKSNLFCSTSGFIVGMVFLQFAYDATFMIIMVWTSVSMVLLLHRHRQRMQHILTPNQNPRGQAETRATRTILMLVVTFVSFYLLNFICIIFHAFSIHSHLFIRLVSVVLAAVFPSICPLLLIFRDPKDPCSVIFKC", "length": 307 }, "evidence": [ { "id": "G3MZM9", "url": "https://omabrowser.org/oma/group/G3MZM9/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "L7N273-1", "protein_name": "Vomeronasal type-1 receptor", "gene_name": "Vmn1r118", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MSVHDKSVKTTEEVALQLLLLCQFGVGTVANVFLFVHNFSPVLTGSKQRPRQVILSHMAVANALTLFLTIFPNNMMAFAPKTPPNELKCKLESFSRLVARSTNLCSTCVLSVHQFVTLFPVSRGKGKLILRASVQNLASYSCYSCWFFSVLSNIHIPIRVTGPQITDNNTDSKSNLFCSTSGFIVGIVLQFAHDATFMSIMIWTSVSMILLLHRHCQRMQDILTPNQNPRGQAETRATRTILMLVVTFVSFYLLNCICIIFHAFFIHSRLFIRLVSEVLAAVFPSICPLLLIFRDPKDPCSLLFKC", "length": 306 }, "evidence": [ { "id": "G3MZM9", "url": "https://omabrowser.org/oma/group/G3MZM9/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "L7N275-1", "protein_name": "Vomeronasal type-1 receptor", "gene_name": "Vmn1r169", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MLSQNKSVKTTVEVALQILLLCQVGVGTVVNIFLFVHNLSPFLNGSQQRPIKVILANLALGNTLILLFAFPNNIRVFIPREFPTDLKCKLGYFIWLVARSTNMCSTCSLSTYQLVTLAPGTWGRVMLHGRAPKFVRYTCYSCWLFSVLNNAHIPMKVSGPQKTHNDTNTKSKWVCSTTGFSIGMRILSFAHDAVFISIIIWSSVSMVILLNRHHQRLQHIQSPNQKLRFHAETRAAHTILMLVVTFVTCYLLDCICTSLHISFVDSRVWLRRVKEILAVSFPTFSPLLLIFRDPKDPCSLPFSC", "length": 304 }, "evidence": [ { "id": "G3MZM9", "url": "https://omabrowser.org/oma/group/G3MZM9/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "L7N288-1", "protein_name": "Vomeronasal type-1 receptor", "gene_name": "Vmn1r151", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MSDHGKSVKTTEEVALQILLLCQFGVGTLANVFLFVHNFYPVLTGSKQRPRQVILSHMAVANALTLFLTIFPNNMIAFAPKTPPTELKCKLEFFSHMVARSTNLCSTCVLSIYQFVTLVLVNRGKLILRASVPNFVSYSCYSCWFFSVLSNIHISIKVTGPQITDNNTDSKSNLFCSTSGFIVGIVSLQFAYDATFMSIMVWTSVSMVLLLHRHRQRMQHILTPNQYRRGQAETRATRTILMLVVTFVSFYLLNFICIIFHTLLMHSHLFIRLVSEVLAAVFPSISPLLLIFRGPKDPCSVLFNC", "length": 305 }, "evidence": [ { "id": "G3MZM9", "url": "https://omabrowser.org/oma/group/G3MZM9/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "L7N2A6-1", "protein_name": "Vomeronasal type-1 receptor", "gene_name": "Vmn1r116", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MSAHGKSVKTTEEVALQILLLCQFGVGTVANVFLFFHNFSPVLTGSKQRPRQVFLSHMAVANALTLFLTIFPNNMSAFAPKTPPNELKCKLEFFSHMVARSKNLCSTCVLSIHQFVTLVPVNRGKGKLILRASVPNLWNYSCYSCWFYSVLSNIHIPIKVTGPQITDNNTDSKSNLFCSTSGFIVGMVFLQFSHDATFMSIMVWTSVSMVLLLHRHRQRMQHILTPNQDARGQAETRATHTILMLVVTFVSFYLLNCICIIFHAFSIHSRLFIRLVSEVLAAVFPSICPLLLIFRDPKDPCSVLFKC", "length": 307 }, "evidence": [ { "id": "G3MZM9", "url": "https://omabrowser.org/oma/group/G3MZM9/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "L7N2B4-1", "protein_name": "Vomeronasal type-1 receptor", "gene_name": "Vmn1r128", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MSAHGKSVKTTEEVALQILLLCQFGVGTVANVFLFVHNFSPVLTGSKKRPRQVILSHMAVANALTLFLTIFPNNMSAFAPKTPPTELKCKLEFFSHMVARSKNLCSTCVLSIHQFVTLVPVNRGKGKLILRASVPNLWNYSCYSCWFYSVLSNIHIPIKVTGPQITDNNTDSKSNLFCSTSGFIVGMVFLQFSHDATFMTIMVWTSVSMVLLLHRHHQRMQHILTPNQDARGQAETRATHTILMLVVTFVSFYLLNCICIIFHAFSIHSRLFIRLVSEVLGAVFPNICPLLLIFRDPKDPFSVLFKC", "length": 307 }, "evidence": [ { "id": "G3MZM9", "url": "https://omabrowser.org/oma/group/G3MZM9/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "L7N2C2-1", "protein_name": "Predicted gene 2974", "gene_name": "Gm2974", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MFSWLLRLFQKENGDEGETRPTEKEEGILSHEKERRKWFWRRHRSARNTSTQNSKMTKKRSKINELEELKLDMRKISNDMEEMCGILNLYMYEDLNYRMNTEFNIIKSQHEKTMLDMNKMIQSIIGSMQYSKELIEDNYSYSIKEDHLLRECTQLNENVRILLNENRRLLVEQAGHKCPVGKKRGSLRRPARTSVSQVPRNSSVI", "length": 205 }, "evidence": [ { "id": "G3MZM9", "url": "https://omabrowser.org/oma/group/G3MZM9/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "L7N474-1", "protein_name": "Spermatogenesis associated glutamate (E)-rich protein 1E", "gene_name": "Speer1e", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "ARRHTSSTAPDLSKKEFKKEKERLTTELHLLIQLRNEQRDHLIDFKESSNYNRTKPTQKKNPFYEQLRSTKNQVLSSVHKLEMGIIEAQENIQELNKWIDYFTNLHSQLLMEKNLKMSITQNQKNKEVEIDWALIEKYLVDVNLNGRTGADQQP", "length": 154 }, "evidence": [ { "id": "G3MZM9", "url": "https://omabrowser.org/oma/group/G3MZM9/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "M0QWR4-1", "protein_name": "Aly/REF export factor family member 14", "gene_name": "Alyreffm17", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MADKMDMSLEDIIKLTKIQQRRHDRPDSRVNRGTGSKRYRPAFTHGGRNRLAPYCRPKQLPDKWQHDLFIGGFRGQNHVDTGGKLFLSNLHFGVSDADIQLLFAEFGTLKKSAVHYDRCGRSLGTAQVHFERKADALKAMREYNGAPLDGRPMNIQLATSQIDRQGRPAQSKNRGGMTRNPGSGVLSGGGTKKWTLGGSQGRGRGTIRNSKLQQQQQQQKQKQQQQQQKQQQKQQQKQQQQLSAEELDAQLDAYQEMMDTS", "length": 261 }, "evidence": [ { "id": "G3MZM9", "url": "https://omabrowser.org/oma/group/G3MZM9/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "M0R3T3-1", "protein_name": "Peptidase S1 domain-containing protein", "gene_name": "ENSRNOG00000067174", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MRFLVLCLILSLGDYGAFPLIQSRIHRGCKGERHSQPWQVAMYHYDKAVGWGWHPSPTTMSTSPSHNKVRLGQHSLDADGDTGQDVPVRHSIPHPLYNRSLQMPTFLSPDADNSHNLMLRQLREPANTTEAVRVTEEPTEEAKLGSRCLASGWGSTRPDKCMPGMLQCVDLTLMSSDVCTYAYSQRVTESMLCAGHQEGSRDTCMGDSGTTLICDRMLQGITSWGGNPCA", "length": 230 }, "evidence": [ { "id": "G3MZM9", "url": "https://omabrowser.org/oma/group/G3MZM9/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "M0R777-1", "protein_name": "non-specific serine/threonine protein kinase", "gene_name": "Smokwl5", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MASKSKEKTLGSHYKILSYLGQGSFGTVNLAWHLKTQALVAIKMLEISKETISSILSERAILETLHHPNIIRLFQVLITSSHVNFVLEYAPGGSLFELIKEGGPLQEEVAKKIFGQTVSAVKYCHNLDIVHRDIKPQNILTDAEGNGKLTDFGLATKFRPGTLLKELCGTKEFYAPELVLREPYNGKKTDVWSLGVLLYFISTGYCPFRGVTTKDMEKKIATGTYTIPTYFSGQLENLIHQILTVSPEMRPSIEDIEKHPWVRKCEVNIPTITCPDYKIVEMLCGMGYNANKILESLQKKKYDEPMAAYLILKDKVRQEIEHGTTTSDMPVDQGPLPPQSPAHHSVSGLPLKRRASEPNFGLLHIWPPGEQVARHNVARSVSMPPIALYGTKKQNSTSTSALHSRPVASPCVCNTILEIEIPLPTKQDFDMKTSSPPQRIGYFQRLCQRIRDCLSRLCCFLWAPKVHSPRKWLP", "length": 474 }, "evidence": [ { "id": "G3MZM9", "url": "https://omabrowser.org/oma/group/G3MZM9/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "M0R9M1-1", "protein_name": "Olfactory receptor family 52 subfamily N member 1B", "gene_name": "Or52n1b", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MSLLNVSSLTPASLILNGIPGLEEVNLCIFFPLFTMYSIALTGNFGLIYLIYSEEVLHRPMYIFLALLSFTDVLMCTSTIPNTLFISWFNFKKIDFKACLAQMFFVHTFTGMESGVLVLMVLDLYIAMCYPLRYATILTNVVIAKAGMLTFLRGVALVIPFIFLTKRFPYCKGNVIPHTYCDHISVAKISCGNVQINAIYGLMVVLLIGDFDIPCITVSYTMILWAAVSLSSADARQKAFSTCTAHICAIVITYVPAFFTFFTHRFGWHTIPSHIHIIMANLYLLMPPTMNPIVYGVKTKQIQKRVIRFFFKGRENSSHKF", "length": 321 }, "evidence": [ { "id": "G3MZM9", "url": "https://omabrowser.org/oma/group/G3MZM9/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "M0R9X6-1", "protein_name": "Paired immunoglobin-like type 2 receptor beta 1 like 2", "gene_name": "Pilrb2l4", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MALLVSLPEQNLAMAWILLLLLLAACLHTGNSAGYQKTQDYGVNQPEQLTGIQGGSIEIPFSFYFPWELAKDPQMSIAWRWKVFFGEVIYNSTLLFLHEHFKGRLIMNWTQGQTSGVLRILNLKANDQSTYFSRIFLQATEGMKLWQSRAGTKLIIHALSTTMASPSIIPSAVPTAGLENTRGQRNPSLLNLGAMVGMVMAKVVVIIPLYGWVIFLWWKQRLPTARISHQVSLHHTPCIPQSSMSSLWESELVAAGFSCESHSWITPTSAMGARIPSPWNQGPPVCLWA", "length": 289 }, "evidence": [ { "id": "G3MZM9", "url": "https://omabrowser.org/oma/group/G3MZM9/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "M0RAD6-1", "protein_name": "Olfactory receptor", "gene_name": "Or1f19f", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MRSTNQSSVSEFLLLGLSRQPQQQQLLFLLFLIMYLATVLGNLLIILVISTDSHLHTPMYFFLSNLSFVDVCFSSTTVPKVLANHILSSQAISFSGCLTQLYFLCVSVNMDNFLLAVMAYDRFVAICHPLYYTTKMTHQLCVLMVSGSWVTASLNALLHTLLMARLSFCGDNIIHHFFCDVTPLLKLSCTATNLNELMILTEGAVIMVTPFVCILISYIYITNAVLRVSSFRGGWKAFSTCGSHLAVVCLFYGTIIAVYFNPVSSHSSEKDTAATVLYTVVTPMLNPFIYSLRNNDLKGALRKVVHRKI", "length": 309 }, "evidence": [ { "id": "G3MZM9", "url": "https://omabrowser.org/oma/group/G3MZM9/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "M0RBH5-1", "protein_name": "Surfactant associated 2", "gene_name": "Sfta2", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MEPSMCLFLLLTLLCSSLAGPTKVTLQVKLTEASQAKTSQDSGFLDMLQKICLLLHLSPGTNVTLHHKGPPHHLTCRA", "length": 78 }, "evidence": [ { "id": "G3MZM9", "url": "https://omabrowser.org/oma/group/G3MZM9/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "M0RCJ6-1", "protein_name": "EF-hand domain-containing protein", "gene_name": "AABR07013776.1", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MADQLTEEQIAEFKEAFPLFDRDGDQTVTTKELGMVMGSLGQNPTEAELQDMISEVDADGNGTINFPEFLTMMARKMKGTDVEEEIREAFRVFDKDGYTSAAEFRHVMTTLGEKLTDEEVDGMIREADMDGDGQVIYEEFVQMVTAK", "length": 147 }, "evidence": [ { "id": "G3MZM9", "url": "https://omabrowser.org/oma/group/G3MZM9/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "M0RCP1-1", "protein_name": "Leukocyte immunoglobulin like receptor B3", "gene_name": "Lilrb3", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MVSTLTALAYLGLILGSENPVLSGAFTKPTIKMVPSNVVTTGKQVTIFCEGSSHAKEYRLHKEGSPDYLTPTTFLETENKAKFSISPIQWNNAGQYWCSYRSLTNKLRQSDIMELVVTGVILGEVTLSALPSYVVTSGRNVTLQCASQVVYDRFILMKEDEKFSTAMPSWKIYPVLWGAIFTLGPVTSNQRWRFTCYGYYLSSSLIWSKPSNHLELLVSGTLHKPILWAHPGSMVTSGSPVTIWCEGDQETQTYVLYRQGSLESWNRQTQKDYNNKAEFTIPSVTYLNAGHYFCYSYTSAGWSEHSDTLELVVTGVYKKPIFLALKNPIVNLGVTVTISCTSNQSFNCFLLMDDDQKIYRFFDLQYSYSGESLARFQVGPITSRQRWRFRCYGYYTDNPQVWSEASDPLDFLVSGNLQKPTLWAEPGSVIESGNSVTIWCEGTMETQIYFLYKEGSPSSWLRQTPKEPGNKAMFFIAFMEKHNAGQYRCYCYNFGGWSQHSDTLELVMTGVHHGKPTLSAFPSPMVTSGGNVTLYCASSTIYDWYIVTGQDLKFSRFQRAQFIPTEMSQALFSEISVASRKKGPFRCYGFNESTPHLWSEASNPLEIHVSGVSRKPSLLNQQGPVLAPGENLTLRCSSELSYDRFSLSKEGRSDLPQLSVSQSQTGEYYANFFLYSVDFSIAGQYRCYGASRFSSEWSAPSVPQDILVTGHPPITPSLSVNPGTIVSSGENVTLLCQSSIPMDTFFLFKKGDAYPYMHQRLKFQGPQCKAEFSLSAVTPNIGGIFTCFGSQSSSPYLLSHPSVPVEIKVSGLAKYQKSLIWVSVVFFLLFFVLTLFFFLRLWHQNKHRKGVQTKIDLQHPEGAVEPKSIVGHLQKSSRPAPAIQEEILCEKRWPGREITEVSASDATVKVTRSADNVELGILSQHQDDPSIHLYAQVKPARLRRAQTTSSSLFPKELQHSKHRQKNRDQVIDQQADTSQDSHAVIYAQLHIMTPRQGRQTSLFPGRIC", "length": 1008 }, "evidence": [ { "id": "G3MZM9", "url": "https://omabrowser.org/oma/group/G3MZM9/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "M0RCQ2-1", "protein_name": "G-protein coupled receptors family 1 profile domain-containing protein", "gene_name": "LOC100361204", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MDSSIPDPEADLIQLNGSYHTETSPCVIESRVMILLSIIIAFFGLAGNAMVLWLLAFRMRRNVFSVYILNLAGANFLFLCTHTAFSLEKIIVLFHSVHIHIPLLFYTLSTLAYLAGVSMVTAISAEYWLSGIWPYWYQGQRLKHTTTVICTGLWGLALLLSLLEGKSCGFLGSTYNQDVCWKLDFIIVAWLLVLFAVLSRSIQVLLVRIFCGSQRTPVTKLHVTIVLTALVLVICGFPFGIIFYLLYWTTEVYYIMPCNSFHETILLLSYINSCANPIICLLVGSIRHCRFQCGTLRLLLHRAMQDIPEEEGEELEEVVGERVQSSIP", "length": 328 }, "evidence": [ { "id": "G3MZM9", "url": "https://omabrowser.org/oma/group/G3MZM9/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "M0RCW7-1", "protein_name": "Uncharacterized protein", "gene_name": "Pilrb1l3", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MALLVSLPEQNLAMAQLLLLLLSAACLHTGNSAGYPKKNVFSVDQPAVLSGVQGGSIEISFSFYFPWELAKVPQMSIAWRWKNYHGEYIYNSTQPFIHEHFKGRLIVNWSQGQTSGVLRILNLKENDKATYFSRVFLPTTEGMKSWQSVAGTQLIIIHAPSTTVVSPSIIPSVVPIAGLEDTRGKRTPSLLNLGAMVRMVVSKVVVIIALYGWVIFLWWKQRSAWSLLSFLTTWKSEEQMQMNTAPAPKEFK", "length": 252 }, "evidence": [ { "id": "G3MZM9", "url": "https://omabrowser.org/oma/group/G3MZM9/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "M0RCY4-1", "protein_name": "Retinoic acid early-inducible protein 1 domain-containing protein", "gene_name": "AABR07000137.1", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MSSAPLGSLGRKSKNQSLGLDMLGTVLSTDSLSCTFTVKYRSSPGQCSVNGKPLLLFNDERQNSPVGKPEKKGNATKVCAELNQSLKDIFQKMMNLESWLFESKGNHTLQVTVQSQYNQGIFMDGCWVFTIDRQYPFYFYPKIMTWRESHPDASRTVSQWQNNRQVAQSLRTCSMGDFSQCLRKLLTDSREVPRSTITTLDPTQPSSAIQIPPTVDSASSVFTTWSQYIFVLILCLAILIINALIP", "length": 246 }, "evidence": [ { "id": "G3MZM9", "url": "https://omabrowser.org/oma/group/G3MZM9/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "M0RD07-1", "protein_name": "Uncharacterized protein", "gene_name": "ENSRNOG00000064269", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MRMMAMQMMTNSISDAMERYKELIQVNSSYNIRQSQLLREQAQLKNNIQILLNEKRELLVEETELPASSVEAKRLCEEAGMNICDPRAKQQQV", "length": 93 }, "evidence": [ { "id": "G3MZM9", "url": "https://omabrowser.org/oma/group/G3MZM9/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "M0RDP5-1", "protein_name": "Zinc finger protein 353", "gene_name": "Zfp353", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MDVAETPGASQTVPCNTQPSPVESSQLVSGQSSEMPTWKKTVMASACCNPQETACTQNSTAHPGKASDFYFGEPSETASFIQQVVSAEQKSSPAGSCLMNLSSTTKSCLSHPLKTEVLDTRKTLCNEGHWGRTLNSDKTLLIQITTMYESQWRTLGNHPVAPSGYHEGQAPNMDHLVDSVSNQTFIGDLEMEPSCNHVLYTDQFITSFSEQNPFGDQQRSPVADNRFYADQKILPNGYQTFYEPQMSTNYQITCVCGQNVCRCQEILLSGEHLLSEYQTSGYRYDQDLIVNLQVTSPIGGEPLHDSQIPNSNFDTTSCGTKRTTSSEEDNLAWHPETSLSSEETFLDQMRTSVDQNVYPSHNGTLKIEESLEPQVTSLSNQAPYVGESSDTSNSPLIQIQPQEISSASGLDQGQHPEIKLDLKTQSPVSLKNPHNSKRYCCTYQGCKKSYKKSQHLKDHMKKHTGVKPYMCNKPGCDWKFFRLVDLNRHKQKHSGERPYPCPMCNKNYSRFYYLKQHLRSHIQASPTTAT", "length": 530 }, "evidence": [ { "id": "G3MZM9", "url": "https://omabrowser.org/oma/group/G3MZM9/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "M9MSI7-1", "protein_name": "Uncharacterized protein", "gene_name": "Dmel\\CG42818", "tax_id": 7227, "organism": "Drosophila melanogaster", "sequence": { "sequence": "MFIHQREQLPFKHNEQDPNYLAPVIQKRKPMDKDPRNPLKRLKFLQEFPTQSSKGDLDDLKYPTQLEGRHDSPKYDKTFHTEIHANNETDSQELENIILEKNLQDSKTEFQENRASQPKNMHSFQIPEAIESHFNNKELQNENDLHKGLKQQYRSGSEQDKSGPENVREIASKLILQWAENQRSLLDSFVKAITDVLKVHDSKLNMKINISPRDIMILKDMLKQLLESIMQLREGSTSTRARIVLNKWIETQKSLIDSFSQAIQNTNQNVDNIANVYEVMENLNKNLRELVILLSDKESFPTTESSSSQQTTSIYATTTFYLTSSTFGSTHPIVDENINRVNIMGNLIKGLRNIMVQMDETNKTSSSTSYTTTESTYIQPSTSTYLNAEVTTSHPTTSTYEVTNIITDESKIKDMFNLIKGIEDLISQYNGKHKFTSTTSLTGKSNSREPTMTTYSSAGGITSHSFTTTSPKTVTTSSSHSTTESSPSHPTTSNYEVTVFDQDSHKFKVMKNLIKELKGLIEHFSDTKNITSTTYSTGDSKSFQPTATTPDSTDRSSSQPITFPESTTSTTNLQSTITNHLSTESTSSQLNTTLSITGTTTPNLTTSTHDFKDQINDDDSKSLKHLIKILSDLVYSLNDKNNIKSTSQLTTESTFNSSINITNSTTVASSTFSTTESMAIHSTPYLSTREITVFQFNDVENINPIISNNSTTVTTNIHSSTYTTSTTDNTTSYPNLSTTESSPTFDSTISHSNTSSQTRSLGSYKDKIKNIVELLKKLRKIQKTLADKSKGQLSPMLISRIKAVLKQIVAGNIDSVNGDSTELEILLSTTVNPNEDTTDLTMEKLLKLFDDFERMYNVLLDDSIQSTTQSTTQNNTIFSTTYSTIFSTTQSISTTSPTQYALTSSTPNTSTTSHSSTPSSINNLRSDESNNHQPIVDAIQQLKMALYHDFYAFKKSQEERMEKILQLLNGKPIDRRTKTIAKPRTIRKKVSREIQKRNSDVKEDKIHHYKADKFIKNPKNGNQDSHIPKPILNSARSKIKDVPLKLSAIKVNGGLKHLPSKRKANEEVSAMHEIFPEPVSILPHK", "length": 1085 }, "evidence": [ { "id": "G3MZM9", "url": "https://omabrowser.org/oma/group/G3MZM9/", "database": "OMA" } ], "glygen_name": "Fruit fly", "common_name": "Fruit fly" }, { "uniprot_canonical_ac": "O08640-1", "protein_name": "Keratin-associated protein 14", "gene_name": "Krtap14", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MSCNSCSGTFSQSFGGQLQYPISSCGSSYPNNVFYSTDLQTPITHQLGSSLHSGCQETFCEPTNCQTAYVVSRPCQRPFYSQRIRGPCRPCQSTFSGSLGFGSRGFQSFGCGYPSQGFGSHGFQSVGCGTPTFSSLNCGSSFYRPTCFSTKSCQSVSYQPTCGTGFF", "length": 167 }, "evidence": [ { "id": "G3MZM9", "url": "https://omabrowser.org/oma/group/G3MZM9/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "O21032-1", "protein_name": "Large ribosomal subunit protein uL16m", "gene_name": "mrpl16", "tax_id": 44689, "organism": "Dictyostelium discoideum", "sequence": { "sequence": "MKIPNRQKFTKNHKRNLITKETRKTGLVLGNYGIKATETGYLKMKQMERIKGDLVKKLKDNMDIYFNFYPLFGLTNKGTARMGAGKGEVSEWYVLVKKGSIVVEFIKSRMTAGAMQKVIRYSANKWPIKVRMTQIKQGLYEKKI", "length": 144 }, "evidence": [ { "id": "G3MZM9", "url": "https://omabrowser.org/oma/group/G3MZM9/", "database": "OMA" } ], "glygen_name": "Cellular slime mold", "common_name": "Social amoeba" }, { "uniprot_canonical_ac": "O21042-1", "protein_name": "Cytochrome c oxidase subunit 1+2", "gene_name": "2", "tax_id": 44689, "organism": "Dictyostelium discoideum", "sequence": { "sequence": "MKILEIYDKQIAEKEGNIFIFISKWIISVDHKNIGTMYTNFSILAGIVGTLLSLVIRMELSTGNMLDGDGQQYNVIVTAHGLIMIFFVVMPAMLGGFANWFIPIMVGSPDVAFPRLNNISLWLIIVSFFLLLTSSCVGIGVGTGWTVYPPLSTMEYHPGHAVDVGILSLHIAGASSLLGAINFLTTVFNMKIAGLSWSKVSLFVWSILITAVLLVLSLPVLAGGLTMLITDRNFETTFFDPIGGGDPILYQHLFWFFGHPEVYILILPGFGLVSIILSKYSNKGIFGVKGMISAMSAIGFLGFLVWAHHMYTVGLDVDTRAYFTAATMIIAIPTGIKIFSWLATLWGGVIKITTPMLFVIGFLVLFTIGGLTGVVLANGGLDISLHDTYYVVAHFHYVLSMGAIFAIFAGYYYYYSIMNSTRLFGVVRYNEQLGRIHFWTMFIGVNVTFFPMHFLGLAGMPRRIGDYPDAYIGWNLIASYGSLITAFGLLFFVVNIFTPYIRRSVNIKNGAIILMGLDFARDWQIGFQDPATPIMEGIIDLHNYIFFYLIVVAVFIGWVMGRILWRFSYKWSYPTIGDIEIFKNFTAYNQIIHGTVIEIVWTLIPTVILYLIAIPSFTLLYAMDEIINPTVTIKIIGHQWYWSYEYGDNASNLIEFDSYMVYERDLAEGQLRLLEVDNAMVVPVKTHIRLIITSGDVLHSWAIPSFGIKVDAVPGRLNQIGLYVKREGTFYGQCSELCGVDHGFMPIKVQAVKLGEYFSKLNEK", "length": 764 }, "evidence": [ { "id": "G3MZM9", "url": "https://omabrowser.org/oma/group/G3MZM9/", "database": "OMA" } ], "glygen_name": "Cellular slime mold", "common_name": "Social amoeba" }, { "uniprot_canonical_ac": "O21049-1", "protein_name": "Cytochrome c oxidase subunit 3", "gene_name": "cox3", "tax_id": 44689, "organism": "Dictyostelium discoideum", "sequence": { "sequence": "MKGFFENLFRQNVRSVINTGKKVGARAAAREIINQEWGYPLANHEVLFLTNVYQPKHMKRHPFHIVRGTVAPLAVTLPLGFFVLNYFGVISSKLGLLIALSSFIGGLVIWTISIIFDSLYDQQHTYEVKRGLVMGMMMFIISEVMFFFSFFWSYFYISLSPNIAIGCVWPPYGLTVYSYMGLPLLNTVLLLLSGAILTDGYTILTEQKAVHEKNEKVLAVEEAFKNLMNLYKTKNSINTLTFVDERRDKFFGKESRQEDKIAEQKLIAISAGVKELRDLDWDLYFFENPENIEPNYKEPTNLSVIEYALITIYLKKRNKVIKTRLYFTLLCAVVFLACQGYEYFFAPFSMNDGIYGSLFFLLTGFHGFHVLVGSILIGIITIRFIVGNFNLLNVGTNFQIYKNKSTGFACTLFYWHFVDIVWIFLYIVIYWWGSR", "length": 435 }, "evidence": [ { "id": "G3MZM9", "url": "https://omabrowser.org/oma/group/G3MZM9/", "database": "OMA" } ], "glygen_name": "Cellular slime mold", "common_name": "Social amoeba" }, { "uniprot_canonical_ac": "O23373-1", "protein_name": "Formin-like protein 3", "gene_name": "FH3", "tax_id": 3702, "organism": "Arabidopsis thaliana", "sequence": { "sequence": "MGRLRLAFLAISLVVFVCVSEEIFSRGGLNLLRFSVYGEDVAEQTWIHQNPRRKLISYPKKFSVSAPNLAFGPAPSFAPGPGPSFAPGPAPNPRSYDWLAPASSPNEPPAETPDESSPSPSEETPSVVAPSQSVPGPPRPPPQREKKDDILMKLIIAVASTAVLTFVFVALMFLCCFKRNCNNAVGSRDGPRDEGPLLRLSTGSTENSPTVASTSRKMFSVASSKKRSFLSRVSLKRNGHEFSTAESSSAAGLPPLKLPPGRSAPPPPPAAAPPPQPPPPPPPKPQPPPPPKIARPPPAPPKGAAPKRQGNTSSGDASDVDSETGAPKTKLKPFFWDKMANPDQKMVWHEISAGSFQFNEEAMESLFGYNDGNKNKNGQKSTDSSLRESPLQYIQIIDTRKAQNLSILLRALNVTTEEVVDAIKEGNELPVELLQTLLKMAPTSEEELKLRLYSGDLHLLGPAERFLKILVDIPFAFKRIESLLFMISLQEEVSGLKEALGTLEVACKKLRNSRLFLKLLEAVLKTGNRMNVGTFRGDAQAFKLDTLLKLSDVKGTDGKTTLLHFVVLEIIRSEGVRALRLQSRSFSSVKTDDSNADSSPQSVERYRSTGLQVVTGLTTELEDVKRAAIIDADGLAATLANISGSLTNAREFLKTMDEESDFERALAGFIERADADFKWLKEEEERIMVLVKSSADYFHGKSAKNEGLRLFAIVRDFLIMLEKVCREVKETTKTTNHSGKKESEMTTSDSNQPSPDFRQRLFPAIAERRMDSSDDSDDEEDSSPS", "length": 785 }, "evidence": [ { "id": "G3MZM9", "url": "https://omabrowser.org/oma/group/G3MZM9/", "database": "OMA" } ], "glygen_name": "Arabidopsis", "common_name": "Mouse-ear cress" }, { "uniprot_canonical_ac": "O35698-1", "protein_name": "RNA-binding motif protein, Y chromosome", "gene_name": "Rbmy", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MAETNQPGKIFIGGLNIKTRQKTLQEIFGRFGPVARVILMRDRETKKSRGFAFLTFRRLADAKNAVKEMNGVILDGKRIKVKQARRPSSLESGSKKRPPSFSRTRGASRILKCGRGGRSRARSGPSCEGNLGGDRYTPNFNVSSSGRHFAVKRNPSSKRDDPPSKRSATSAQTRSNTGLRGREPHRREISRNMPRGEPASSRRDEYPLPRDYGQSSNDRKYESTSRGYCDYGNYHSREESASKVFSDHAGYLGGRDRDFSEYLSGNSYRDTYRSYGRFHEAPSARGGNNRYDDYSNSQDGYGGRGEPYISNRSNIYSSDYERSGRQEVLPPPIDREYFDREGRQERGHSPKDGLYSASRESYSSNTKIWGIPWRSWRKQI", "length": 380 }, "evidence": [ { "id": "G3MZM9", "url": "https://omabrowser.org/oma/group/G3MZM9/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "O60309-1", "protein_name": "Leucine-rich repeat-containing protein 37A3", "gene_name": "LRRC37A3", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MTSAQCPALACVMSPLRFWGPWPLLMWQLLWLLVKEAQPLEWVKDPLQLTSNPLGPPEPWSSHSSHFPRESPHAPTLPADPWDFDHLGPSASSEMPAPPQESTENLVPFLDTWDSAGELPLEPEQFLASQQDLKDKLSPQERLPVSPKKLKKDPAQRWSLAEIIGIIHQLSTPQSQKQTLQNEYSSTDTPYPGSLPPELRVKSDEPPGPSEQVGPSQFHLEPETQNPETLEDIQSSSLQQEAPAQLPQLLEEEPSSMQQEAPALPPESSMESLTLPNHEVSVQPPGEDQAYYHLPNITVKPADVEVTITSEPTNETESSQAQQETPIQFPEEVEPSATQQEAPIEPPVPPMEHELSISEQQQPVQPSESSREVESSPTQQETPGQPPEHHEVTVSPPGHHQTHHLASPSVSVKPPDVQLTIAAEPSAEVGTSLVHQEATTRLSGSGNDVEPPAIQHGGPPLLPESSEEAGPLAVQQETSFQSPEPINNENPSPTQQEAAAEHPQTAEEGESSLTHQEAPAQTPEFPNVVVAQPPEHSHLTQATVQPLDLGFTITPESMTEVELSPTMKETPTQPPKKVVPQLRVYQGVTNPTPGQDQAQHPVSPSVTVQLLDLGLTITPEPTTEVGHSTPPKRTIVSPKHPEVTLPHPDQVQTQHSHLTRATVQPLDLGFTITPKSMTEVEPSTALMTTAPPPGHPEVTLPPSDKGQAQHSHLTQATVQPLDLELTITTKPTTEVKPSPTTEETSTQLPDLGLAIIPEPTTETGHSTALEKTTAPRPDRVQTLHRSLTEVTGPPTELEPAQDSLVQSESYTQNKALTAPEEHKASTSTNICELCTCGDEMLSCIDLNPEQRLRQVPVPEPNTHNGTFTILNFQGNYISYIDGNVWKAYSWTEKLILRENNLTELHKDSFEGLLSLQYLDLSCNKIQSIERHTFEPLPFLKFINLSCNVITELSFGTFQAWHGMQFLHKLILNHNPLTTVEDPYLFKLPALKYLDMGTTLVPLTTLKNILMMTVELEKLIVPSHMACCLCQFKNSIEAVCKTVKLHCNSACLTNTTHCPEEASVGNPEGAFMKVLQARKNYTSTELIIEPEEPSDSSGINLSGFGSEQLDTNDESDVTSTLSYILPYFSAVNLDVKSLLLPFIKLPTTGNSLAKIQTVGKNRQRLNRVLMGPRSIQKRHFKEVGRQSIRREQGAQASVENTAEEKRLGSPAPRELKQPHTQQGPEKLAGNAVYTKPSFTQEHKAAVSVLKPFSKGAPSTSSPAKALPQVRDRWKDLTHAISILESAKARVTNMKTSKPIVHSRKKYRFHKTRSRMTHRTPKVKKSPKVRKKSYLSRLMLSNRLPFSAAKSLINSPSQGAFSSLRDLSPQENPFLEVSAPSEHFIENNNTKDTTARNAFEENVFMENTNMPEGTISENTNYNHPPEADSAGTAFNLGPTVKQTETKWEYNNVGTDLSPEPKSFNYPLLSSPGDQFEIQLTQQLQSVIPNNNVRRLIAHVIRTLKMDCSGAHVQVTCAKLVSRTGHLMKLLSGQQEVKASKIEWDTDQWKTENYINESTEAQSEQKEKSLEFTKELPGYGYTKKLILALIVTGILTILIILLCLIEICCHRRSLQEDEEGFSRDSEAPTEEESEALP", "length": 1634 }, "evidence": [ { "id": "G3MZM9", "url": "https://omabrowser.org/oma/group/G3MZM9/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "O80489-1", "protein_name": "small monomeric GTPase", "gene_name": "SARA1A", "tax_id": 3702, "organism": "Arabidopsis thaliana", "sequence": { "sequence": "MFLFDWFYGILASLGLCKKEAKILFLGLDNAGKTTLLHMLKDERLVQHQPTQHPTSEELSIGKINFKAFDLGGHQIARRVWKDCYAKVDAVVYLVDAYDRDRFVESKRELDALLSDEALANVPCLILGNKIDIPYASSEDELRYYLGLTNFTTGKGIVNLEDSGVRPLEVFMCSIVRKMGYGEGFKWLSQYIK", "length": 193 }, "evidence": [ { "id": "G3MZM9", "url": "https://omabrowser.org/oma/group/G3MZM9/", "database": "OMA" } ], "glygen_name": "Arabidopsis", "common_name": "Mouse-ear cress" }, { "uniprot_canonical_ac": "O80614-1", "protein_name": "RING-type E3 ubiquitin transferase", "gene_name": "", "tax_id": 3702, "organism": "Arabidopsis thaliana", "sequence": { "sequence": "MSSDMRDERFFYHRYLSVTNRTTPTTATNLPTSTSNMRSTSLMTPRVAHTSMSSGGDFPDDRFFHARHQSATDRAASNRSRAIMPISTTNVPSSTSNSPRVLQTSMSRRGTSPMSSSTRRSVQASMSARETVPSSTSTRSMQTSTSTPEIMPTSSRNVITSSEEVANTFTQTSYIQFGSLWETNTTPSTRSWPTVPSSNSPRVLQTSMSRRGTSPMSSSTRRNVQSSMSGRETVSSSTSTSSMQTSMSTPEIMPTSSRNVITRSEEVANTFSTQTPYIQFGRLWETNTTSSTRSRTTVPTSTTNVPSSNSSRVLQTSMSTRGTFPMSSSTRMSVQASMLAPGTVSSSMSTVEIMPTSARNMITMSEEVANSFTQTSYIQFGSLWETFKTVTKLSRVAMVENGECVICLEEWRKETYVTSSTSNMRTSSLMTLTRFIDEQISLRATVSSTRTTARLLTNESPATIRAVAMLPRVAMVEKGECVICFEEWSKSDMETELPCKHKYHLECVEKWLKIHTSCPQCRYKLSCVYKSFLML", "length": 535 }, "evidence": [ { "id": "G3MZM9", "url": "https://omabrowser.org/oma/group/G3MZM9/", "database": "OMA" } ], "glygen_name": "Arabidopsis", "common_name": "Mouse-ear cress" }, { "uniprot_canonical_ac": "O81153-1", "protein_name": "Proteasome subunit beta type-3-B", "gene_name": "PBC2", "tax_id": 3702, "organism": "Arabidopsis thaliana", "sequence": { "sequence": "MSIFEYNGSAVVAMVGKNCFAIASDRRLGVQLQTIATDFQRISKIHDHLFIGLSGLATDVQTLYQRLVFRHKLYQLREERDMKPETFASLVSAILYEKRFGPFLCQPVIAGLGDDNKPFICTMDSIGAKELAKDFVVSGTASESLYGACEAMFKPDMEAEELFETISQALLSSVDRDCLSGWGGHVYVVTPKEVKERILKGRMD", "length": 204 }, "evidence": [ { "id": "G3MZM9", "url": "https://omabrowser.org/oma/group/G3MZM9/", "database": "OMA" } ], "glygen_name": "Arabidopsis", "common_name": "Mouse-ear cress" }, { "uniprot_canonical_ac": "P00757-1", "protein_name": "Kallikrein 1-related peptidase-like b4", "gene_name": "Klk1b4", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MWFLILFLALSLGGIDAAPPVQSQVDCENSQPWHVAVYRFNKYQCGGVLLDRNWVLTAAHCYNDKYQVWLGKNNFLEDEPSDQHRLVSKAIPHPDFNMSLLNEHTPQPEDDYSNDLMLLRLSKPADITDVVKPITLPTEEPKLGSTCLASGWGSTTPIKFKYPDDLQCVNLKLLPNEDCDKAHEMKVTDAMLCAGEMDGGSYTCEHDSGGPLICDGILQGITSWGPEPCGEPTEPSVYTKLIKFSSWIRETMANNP", "length": 256 }, "evidence": [ { "id": "G3MZM9", "url": "https://omabrowser.org/oma/group/G3MZM9/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "P01241-1", "protein_name": "Somatotropin", "gene_name": "GH1", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MATGSRTSLLLAFGLLCLPWLQEGSAFPTIPLSRLFDNAMLRAHRLHQLAFDTYQEFEEAYIPKEQKYSFLQNPQTSLCFSESIPTPSNREETQQKSNLELLRISLLLIQSWLEPVQFLRSVFANSLVYGASDSNVYDLLKDLEEGIQTLMGRLEDGSPRTGQIFKQTYSKFDTNSHNDDALLKNYGLLYCFRKDMDKVETFLRIVQCRSVEGSCGF", "length": 217 }, "evidence": [ { "id": "G3MZM9", "url": "https://omabrowser.org/oma/group/G3MZM9/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "P02762-1", "protein_name": "Major urinary protein 6", "gene_name": "Mup6", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MKMLLLLCLGLTLVCVHAEEASSTGRNFNVEKINGEWHTIILASDKREKIEDNGNFRLFLEQIHVLENSLVLKFHTVRDEECSELSMVADKTEKAGEYSVTYDGFNTFTIPKTDYDNFLMAHLINEKDGETFQLMGLYGREPDLSSDIKERFAQLCEEHGILRENIIDLSNANRCLQARE", "length": 180 }, "evidence": [ { "id": "G3MZM9", "url": "https://omabrowser.org/oma/group/G3MZM9/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "P04071-1", "protein_name": "Kallikrein 1-related peptidase b16", "gene_name": "Klk1b16", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MWFLILFLALSLGGIDAAPPVQSRIVGGFKCEKNSQPWQVAVYYHKEHICGGVLLDRNWVLTAAHCYVDECEVWLGKNQLFQEEPSAQNRLVSKSFPHPGFNMTLLTFEKLPPGADFSNDLMLLRLSKPADITDVVKPIDLPTKEPKLDSTCLVSGWGSITPTKWQKPDDLQCMFTKLLPNENCAKAYLLKVTDVMLCTIEMGEDKGPCVGDSGGPLICDGVLQGTVSIGPDPCGIPGVSAIYTNLVKFNSWIKDTMMKNA", "length": 261 }, "evidence": [ { "id": "G3MZM9", "url": "https://omabrowser.org/oma/group/G3MZM9/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "P04644-1", "protein_name": "Small ribosomal subunit protein eS17", "gene_name": "Rps17", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MGRVRTKTVKKAARVIIEKYYTRLGNDFHTNKRVCEEIAIIPSKNLRNKIAGYVTHLMKRIQRGPVRGISIKLQEEERERRDNYVPEVSALDQEIIEVDPDTKEMLKLLDFGSLSNLQVTQPTVGMNFKTPRGAV", "length": 135 }, "evidence": [ { "id": "G3MZM9", "url": "https://omabrowser.org/oma/group/G3MZM9/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "P05817-1", "protein_name": "Prestalk D11 protein", "gene_name": "ampA", "tax_id": 44689, "organism": "Dictyostelium discoideum", "sequence": { "sequence": "MLNKLILLLILSSCLVLSVKSEVNVDCSLVRCAQPICKPHYRLNMTDSCCGRCEPCTDVACTLQVKYCQDGEVPTGCCPCTLPPTKPDCSLVKCARPVCKPYYRLNMTDSCCGRCEPCTGVACTLQIKYCKDGEVPTGCCPCTPQPTKKPDCSKVPCPKILKYCQEGELPTGCCPCTPQPTKKPDCSRVPCPKILKYCKEGELPTGCCPCTPQPTKKPDCSDVMCTMDIRYCKNGELPTGCCPCTPQETKVPDCSKAMCTMDIKYCKPGEKPFGCCPCRENLTQ", "length": 284 }, "evidence": [ { "id": "G3MZM9", "url": "https://omabrowser.org/oma/group/G3MZM9/", "database": "OMA" } ], "glygen_name": "Cellular slime mold", "common_name": "Social amoeba" }, { "uniprot_canonical_ac": "P06325-1", "protein_name": "T-cell receptor gamma chain V region 5/10-13", "gene_name": "Tcrg-V1", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MLLLRWPTFCCLWVFGLGQLEQTELSVTRATDESAQISCIVSLPYFSNTAIHWYRQKAKKFEYLIYVSTNYNQRPLGGKNKKIEASKDFQTSTSTLKINYLKKEDEATYYCAVCRSGTSWVKIFAKGTKLVVIPP", "length": 135 }, "evidence": [ { "id": "G3MZM9", "url": "https://omabrowser.org/oma/group/G3MZM9/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "P06349-1", "protein_name": "Histone H1t", "gene_name": "H1-6", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MSETAPAASSTLVPAPVEKPATKRRGKKPGMATARKPRGFSVSKLIPEALSMSQERAGMSLAALKKALAAAGYDVEKNNSRIKLALKRLVNKGVLVQTKGTGASGSFKLSKKAASGNDKGKGKKSASAKAKKLGLSRASRSPKSSKTKVVKKPKATPTKGSGSRRKTKGAKGLQQRKSPAKARATNSNSGKSKMVMQKTDLRKAAGRK", "length": 208 }, "evidence": [ { "id": "G3MZM9", "url": "https://omabrowser.org/oma/group/G3MZM9/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "P07628-1", "protein_name": "Kallikrein 1-related peptidase b8", "gene_name": "Klk1b8", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MRFLILFLALSLGGIDAAPPLQSRVVGGFNCEKNSQPWQVAVYDNKEHICGGVLLERNWVLTAAHCYVDQYEVWLGKNKLFQEEPSAQHRLVSKSFPHPGFNMSLLTLKEIPPGADFSNDLMLLRLSKPADITDAVKPITLPTKESKLGSTCLASGWGSITPTKWQKPDDLQCVFLKLLPIKNCIENHNVKVTDVMLCAGEMSGGKNICKGDSGGPLICDSVLQGITSTGPIPCGKPGVPAMYTNLIKFNSWIKDTMTKNS", "length": 261 }, "evidence": [ { "id": "G3MZM9", "url": "https://omabrowser.org/oma/group/G3MZM9/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "P07647-1", "protein_name": "Submandibular glandular kallikrein-9", "gene_name": "Klk9", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MWFLILFLALSLGQIDAAPPGQSRVVGGYNCETNSQPWQVAVIGTTFCGGVLIDPSWVITAAHCYSKNYRVLLGRNNLVKDEPFAQRRLVSQSFQHPDYIPVFMRNHTRQRAYDHNNDLMLLHLSKPADITGGVKVIDLPTEEPKVGSICLASGWGMTNPSEMKLSHDLQCVNIHLLSNEKCIETYKNIETDVTLCAGEMDGGKDTCTGDSGGPLICDGVLQGLTSGGATPCAKPKTPAIYAKLIKFTSWIKKVMKENP", "length": 259 }, "evidence": [ { "id": "G3MZM9", "url": "https://omabrowser.org/oma/group/G3MZM9/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "P08932-1", "protein_name": "T-kininogen 2", "gene_name": "", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MKLITILLLCSRLLPSLAQEEGAQEMDCNDETVFQAVDTALKKYNAELESGNQFLLYRVTEGTKKDGAETLYSFKYQIKEGNCSVQSGLTWQDCDFKDAEEAATGECTTTLGKKENKFSVATQICNITPGKGPKKTEEDLCVGCFQPIPMDSSDLKPVLKHAVEHFNNNTKHTHLFALTEVKSAHSQVVAGMNYKIIYSIVQTNCSKEDFPFLREDCVPLPYGDHGECRGHTYVDIHNTIAGFSQSCDLYPGDDLFSLLPKKCFGCPKNIPVDSPELKEALGHSIAQLNAQHNHLFYFKIDTVKKATSQVVAGTKYVIEFIARETNCSKQTNTELTADCETKHLGQSLNCNANVYMRPWENKVVPTVRCQALDMMISRPPGFSPFRLVQVQETKEGTTRLLNSCEYKGRLSKAGAGPAPDHQAEASTVTP", "length": 430 }, "evidence": [ { "id": "G3MZM9", "url": "https://omabrowser.org/oma/group/G3MZM9/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "P0C0S7-1", "protein_name": "Histone H2A.Z", "gene_name": "H2az1", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MAGGKAGKDSGKAKTKAVSRSQRAGLQFPVGRIHRHLKSRTTSHGRVGATAAVYSAAILEYLTAEVLELAGNASKDLKVKRITPRHLQLAIRGDEELDSLIKATIAGGGVIPHIHKSLIGKKGQQKTV", "length": 128 }, "evidence": [ { "id": "G3MZM9", "url": "https://omabrowser.org/oma/group/G3MZM9/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "P0C2B7-1", "protein_name": "Large ribosomal subunit protein mL52", "gene_name": "MRPL52", "tax_id": 9913, "organism": "Bos taurus", "sequence": { "sequence": "MAALGMLLSTGVRRLHCGSAARAGSQWRLRQGLAANPSGYGPLTELPDWSYADGRPAPPMKGQLRRKAQREKFARRVVLLSQEMDAGLQAWQLRQQEKLQEEKRKQQNALKPKGVLLQNPGPSQ", "length": 124 }, "evidence": [ { "id": "G3MZM9", "url": "https://omabrowser.org/oma/group/G3MZM9/", "database": "OMA" } ], "glygen_name": "Bovine", "common_name": "Bovine" }, { "uniprot_canonical_ac": "P0C644-1", "protein_name": "Inositol hexakisphosphate and diphosphoinositol-pentakisphosphate kinase 1", "gene_name": "Ppip5k1", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MWSLTANEDEDESATAHFFLGAGDEGLGTCGIGMRTGESDSELLEDEEDEVPPEPQIIVGICAMTKKSKSKPMTQILERLCRFDYLTVVILGEDVILNEPVENWPPCHCLISFHSKGFPLDKAVAYSKLRNPFLINDLTMQYYIQDRREVYRILQEEGIDLPRYAVLNRDPACPEECNLIEGEDQVEVNGAVFPKPFVEKPVSAEDHNVYIYYPSSAGGGSQRLFRKIGSRSSVYSPESSVRKTGSYIYEEFMPTDGTDVKVYTVGPDYAHAEARKSPALDGKVERDSEGKEVRYPVMLTAMEKLVARKVCVAFKQTVCGFDLLRANGHSFVCDVNGFSFVKNSMKYYDDCAKILGNTIMRELAPQFQIPWSIPTEAEDIPIVPTTSGTMMELRCVIAIIRHGDRTPKQKMKMEVTHPRFFALFEKHGGYKTGKLKLKRPEQLQEVLDITRLLLAELEKEPGAEIEEKTGKLEQLKSVLEMYGHFSGINRKVQLTYYPHGVKASSEGQDLQREPPAPSLLLVLKWGGELTPDGRVQAEELGRAFRCMYPGGQGDYAGFPGCGLLRLHSTFRHDLKIYASDEGRVQMTAAAFAKGLLALEGELTPILVQMVKSANMNGLLDSDSDSLSSCQHRVKARLHHILQQDAPFGPEDYDQLAPTGSTSLLNSMSVIQNPVKVCDQVFALIENLTHQIRERMQDPSSVDLQLYHSETLELMLQRWSKLERDFRQKSGRYDISKIPDIYDCVKYDVQHNGSLGLQGTAELLRLSKALADVVIPQEYGISREEKVEIAVGFCLPLLRKILLDLQRTHEDESVNKLHPLYSRGVLSPGRHVRTRLYFTSESHVHSLLSVFRYGGLLDETKDAQWQRALAYLSAISELNYMTQIVIMLYEDNTRDPLSEERFHVELHFSPGVKGVEEGSAPAGCGFRPASSENEEMKTDPGSIENLCPAKPSDEPDRALQTSPQPVEGTGLPRRSPLIRNRKAGSMEVLSETSSSRPGGYRLFSSSRPPTEMKQSGLGSQCTGLFSTTVLGGSSSAPNLQDYARTHGKKLPPAGLKHRDELLFVPAVKRFSVSFAKHPTNGFEGCSMVPTIYPLETLHNALSLRQVSEFLTKVCQRHTDAHAQASAALFDSMHNHQASDNPFSPPRTLHSPPLQLRHRSEKPPWYSSGPSSTVSSAGPSSPTTVDGNSHFGFSDQSSVNTQMIEEKQGLGLLQETPGDGTPEFHIELAESTQSPQEPPVEISPPGSQDDTEVNQTCQEVPDTIQPCHDILEEIGQPNQEVPDISQLLLKNHDTATNTCQPCQASQLSKKVYEEICQLCQDNPEESNQLCQEVSVELGRMVHRFPVSIGSTTQETLMEIGRPTQEIPEEPCQEFSEKVGMLTQKASAISELSQDILETDNPSQELSEETDLQAQEVSEEIDQEPEVVDELSNEDIS", "length": 1434 }, "evidence": [ { "id": "G3MZM9", "url": "https://omabrowser.org/oma/group/G3MZM9/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "P0C7H9-1", "protein_name": "Inactive ubiquitin carboxyl-terminal hydrolase 17-like protein 7", "gene_name": "USP17L7", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MEDDSLYLGGDWQFNHFSKLTSSRLDAAFAEIQRTSLSEKSPLSSETRFDLCDDLAPVARQLAPREKLPLSSRRPAAVGAGLQKIGNTFYVNVSLQCLTYTLPLSNYMLSREDSQTCHLHKCCMFCTMQAHITWALHSPGHVIQPSQVLAAGFHRGEQEDAHEFLMFTVDAMKKACLPGHKQLDHHSKDTTLIHQIFGAYWRSQIKYLHCHGVSDTFDPYLDIALDIQAAQSVKQALEQLVKPKELNGENAYHCGLCLQKAPASKTLTLPTSAKVLILVLKRFSDVTGNKLAKNVQYPKCRDMQPYMSQQNTGPLVYVLYAVLVHAGWSCHNGHYFSYVKAQEGQWYKMDDAEVTASGITSVLSQQAYVLFYIQKSEWERHSESVSRGREPRALGAEDTDRPATQGELKRDHPCLQVPELDEHLVERATQESTLDHWKFPQEQNKTKPEFNVRKVEGTLPPNVLVIHQSKYKCGMKNHHPEQQSSLLNLSSTKPTDQESMNTGTLASLQGSTRRSKGNNKHSKRSLLVCQ", "length": 530 }, "evidence": [ { "id": "G3MZM9", "url": "https://omabrowser.org/oma/group/G3MZM9/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "P0CW02-1", "protein_name": "Lymphocyte antigen 6C1", "gene_name": "Ly6c1", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MDTSHTTKSCVLILLVALLCAERAQGLQCYECYGVPIETSCPAVTCRASDGFCIAQNIELIEDSQRRKLKTRQCLSFCPAGVPIRDPNIRERTSCCSEDLCNAAVPTAGSTWTMAGVLLFSLSSVVLQTLL", "length": 131 }, "evidence": [ { "id": "G3MZM9", "url": "https://omabrowser.org/oma/group/G3MZM9/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "P0DKL4-1", "protein_name": "Spliceosome-associated protein 130 A", "gene_name": "SAP130A", "tax_id": 3702, "organism": "Arabidopsis thaliana", "sequence": { "sequence": "MYLYSLTLQQATGIVCAINGNFSGGKTQEIAVARGKILDLLRPDENGKIQTIHSVEVFGAIRSLAQFRLTGAQKDYIVVGSDSGRIVILEYNKEKNVFDKVHQETFGKSGCRRIVPGQYVAVDPKGRAVMIGACEKQKLVYVLNRDTTARLTISSPLEAHKSHTICYSLCGVDCGFDNPIFAAIELDYSEADQDPTGQAASEAQKHLTFYELDLGLNHVSRKWSNPVDNGANMLVTVPGGADGPSGVLVCAENFVIYMNQGHPDVRAVIPRRTDLPAERGVLVVSAAVHKQKTMFFFLIQTEYGDVFKVTLDHNGDHVSELKVKYFDTIPVASSICVLKLGFLFSASEFGNHGLYQFQAIGEEPDVESSSSNLMETEEGFQPVFFQPRRLKNLVRIDQVESLMPLMDMKVLNIFEEETPQIFSLCGRGPRSSLRILRPGLAITEMAVSQLPGQPSAVWTVKKNVSDEFDAYIVVSFTNATLVLSIGEQVEEVNDSGFLDTTPSLAVSLIGDDSLMQVHPNGIRHIREDGRINEWRTPGKRSIVKVGYNRLQVVIALSGGELIYFEADMTGQLMEVEKHEMSGDVACLDIAPVPEGRKRSRFLAVGSYDNTVRILSLDPDDCLQILSVQSVSSAPESLLFLEVQASIGGDDGADHPANLFLNSGLQNGVLFRTVVDMVTGQLSDSRSRFLGLKPPKLFSISVRGRSAMLCLSSRPWLGYIHRGHFHLTPLSYETLEFAAPFSSDQCAEGVVSVAGDALRIFMIDRLGETFNETVVPLRYTPRKFVLHPKRKLLVIIESDQGAFTAEEREAARKECFEAGGVGENGNGNADQMENGADDEDKEDPLSDEQYGYPKAESEKWVSCIRVLDPKTATTTCLLELQDNEAAYSVCTVNFHDKEYGTLLAVGTVKGMQFWPKKNLVAGFIHIYRFVEDGKSLELLHKTQVEGVPLALCQFQGRLLAGIGPVLRLYDLGKKRLLRKCENKLFPNTIISIQTYRDRIYVGDIQESFHYCKYRRDENQLYIFADDCVPRWLTASHHVDFDTMAGADKFGNVYFVRLPQDLSEEIEEDPTGGKIKWEQGKLNGAPNKVDEIVQFHVGDVVTCLQKASMIPGGSESIMYGTVMGSIGALHAFTSRDDVDFFSHLEMHMRQEYPPLCGRDHMAYRSAYFPVKDVIDGDLCEQFPTLPMDLQRKIADELDRTPAEILKKLEDARNKII", "length": 1214 }, "evidence": [ { "id": "G3MZM9", "url": "https://omabrowser.org/oma/group/G3MZM9/", "database": "OMA" } ], "glygen_name": "Arabidopsis", "common_name": "Mouse-ear cress" }, { "uniprot_canonical_ac": "P0DKL6-1", "protein_name": "Spliceosome-associated protein 130 B", "gene_name": "SAP130B", "tax_id": 3702, "organism": "Arabidopsis thaliana", "sequence": { "sequence": "MYLYSLTLQQATGIVCAINGNFSGGKTQEIAVARGKILDLLRPDENGKIQTIHSVEVFGAIRSLAQFRLTGAQKDYIVVGSDSGRIVILEYNKEKNVFDKVHQETFGKSGCRRIVPGQYVAVDPKGRAVMIGACEKQKLVYVLNRDTTARLTISSPLEAHKSHTICYSLCGVDCGFDNPIFAAIELDYSEADQDPTGQAASEAQKHLTFYELDLGLNHVSRKWSNPVDNGANMLVTVPGGADGPSGVLVCAENFVIYMNQGHPDVRAVIPRRTDLPAERGVLVVSAAVHKQKTMFFFLIQTEYGDVFKVTLDHNGDHVSELKVKYFDTIPVASSICVLKLGFLFSASEFGNHGLYQFQAIGEEPDVESSSSNLMETEEGFQPVFFQPRRLKNLVRIDQVESLMPLMDMKVLNIFEEETPQIFSLCGRGPRSSLRILRPGLAITEMAVSQLPGQPSAVWTVKKNVSDEFDAYIVVSFTNATLVLSIGEQVEEVNDSGFLDTTPSLAVSLIGDDSLMQVHPNGIRHIREDGRINEWRTPGKRSIVKVGYNRLQVVIALSGGELIYFEADMTGQLMEVEKHEMSGDVACLDIAPVPEGRKRSRFLAVGSYDNTVRILSLDPDDCLQILSVQSVSSAPESLLFLEVQASIGGDDGADHPANLFLNSGLQNGVLFRTVVDMVTGQLSDSRSRFLGLKPPKLFSISVRGRSAMLCLSSRPWLGYIHRGHFHLTPLSYETLEFAAPFSSDQCAEGVVSVAGDALRIFMIDRLGETFNETVVPLRYTPRKFVLHPKRKLLVIIESDQGAFTAEEREAARKECFEAGGVGENGNGNADQMENGADDEDKEDPLSDEQYGYPKAESEKWVSCIRVLDPKTATTTCLLELQDNEAAYSVCTVNFHDKEYGTLLAVGTVKGMQFWPKKNLVAGFIHIYRFVEDGKSLELLHKTQVEGVPLALCQFQGRLLAGIGPVLRLYDLGKKRLLRKCENKLFPNTIISIQTYRDRIYVGDIQESFHYCKYRRDENQLYIFADDCVPRWLTASHHVDFDTMAGADKFGNVYFVRLPQDLSEEIEEDPTGGKIKWEQGKLNGAPNKVDEIVQFHVGDVVTCLQKASMIPGGSESIMYGTVMGSIGALHAFTSRDDVDFFSHLEMHMRQEYPPLCGRDHMAYRSAYFPVKDVIDGDLCEQFPTLPMDLQRKIADELDRTPAEILKKLEDARNKII", "length": 1214 }, "evidence": [ { "id": "G3MZM9", "url": "https://omabrowser.org/oma/group/G3MZM9/", "database": "OMA" } ], "glygen_name": "Arabidopsis", "common_name": "Mouse-ear cress" }, { "uniprot_canonical_ac": "P0DML3-1", "protein_name": "Chorionic somatomammotropin hormone 2", "gene_name": "CSH2", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MAAGSRTSLLLAFALLCLPWLQEAGAVQTVPLSRLFDHAMLQAHRAHQLAIDTYQEFEETYIPKDQKYSFLHDSQTSFCFSDSIPTPSNMEETQQKSNLELLRISLLLIESWLEPVRFLRSMFANNLVYDTSDSDDYHLLKDLEEGIQTLMGRLEDGSRRTGQILKQTYSKFDTNSHNHDALLKNYGLLYCFRKDMDKVETFLRMVQCRSVEGSCGF", "length": 217 }, "evidence": [ { "id": "G3MZM9", "url": "https://omabrowser.org/oma/group/G3MZM9/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "P0DMV2-1", "protein_name": "Cancer/testis antigen family 45 member A9", "gene_name": "CT45A9", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MTDKTEKVAVDPETVFKRPRECDSPSYQKRQRMALLARKQGAGDSLIAGSAMSKEKKLMTGHAIPPSQLDSQIDDFTGFSKDRMMQKPGSNAPVGGNVTSSFSGDDLECRETAFSPKSQQEINADIKRQLVKELRCVGQKYEKIFEMLEGVQGPTAVRKRFFESIIKEAARCMRRDFVKHLKKKLKRMI", "length": 189 }, "evidence": [ { "id": "G3MZM9", "url": "https://omabrowser.org/oma/group/G3MZM9/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "P0DOV1-1", "protein_name": "Interferon-activable protein 211", "gene_name": "Ifi211", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MVNEYKRIVLLRGLECINKHYFSLFKSLLARDLNLERDNQEQYTTIQIANMMEEKFPADSGLGKLIEFCEEVPALRKRAEILKKERSEVTGETSLEKNGQEAGPATPTSTTSHMLASERGETSATQEETSTAQAGTSTAQAGTSTAQAGTSTAQKRKSMREEETGVKKSKAAKEPDQPPCCEEPTAMCQSPILHSSSSASSNILSAKNQKSQPQNQNIPRGAVLHSEPLTVMVLTATDPFEYESPEHEVKNMFHATVATVSQYFHVKVFNIDLKEKFTKNNFITISNYFESKGILEINETSSVLEAAPKQMIEVPNCITRNANASPKICDIQKGTSGTVFYGVFTLHKKKVKTQNTSYEIKDGSGSIEVVGSGQWHNINCKEGDKLHLFCFHLKRERGQPKLVCGDHSFVKVTKAGKKKEASTVQ", "length": 425 }, "evidence": [ { "id": "G3MZM9", "url": "https://omabrowser.org/oma/group/G3MZM9/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "P0DTA3-1", "protein_name": "Speedy protein E11", "gene_name": "SPDYE11", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MGQILGKIMMSHQPQPQEERSPQRSTSGYPLQEVVDDEVSGPSAPGVDPSPPRRSLGWKRKRECLDESDDEPEKELAPEPEETWVAETLCGLKMKAKRRRVSLVLPEYYEAFNRLLEDPVIKRLLAWDKDLRVSDKYLLAMVIAYFSRAGLPSWQYQRIHFFLALYLANDMEEDDEAPKQNIFYFLYEETRSHIPLLSELWFQLCRYMNPRARKNCSQIALFRKYRFHFFCSMRCRAWVSLEELEEIQAYDPEHWVWARDRAHLS", "length": 265 }, "evidence": [ { "id": "G3MZM9", "url": "https://omabrowser.org/oma/group/G3MZM9/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "P0DUD3-1", "protein_name": "Speedy protein E14", "gene_name": "SPDYE14", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MGQILGKIMMSHQPQPQEERSPQRSTSGYPLQEVVDDEVLGPSAPGVDPSPPRRSLGWKRKRECLDESDDEPEKELAPEPEETWVAETLCGLKMKAKRRRVSLVLPEYYEAFNRLLEDPVIKRLLAWDKDLRVSDKYLLAMVIAYFSRAGLPSWQYQRIHFFLALYLANDMEEDDEAPKQNIFYFLYEETRSHIPLLSELWFQLCRYMNPRARKNCSQIALFRKYRFHFFCSMRCRAWVSLEELEEIQAYDPEHWVWARDRAHLS", "length": 265 }, "evidence": [ { "id": "G3MZM9", "url": "https://omabrowser.org/oma/group/G3MZM9/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "P0DUD4-1", "protein_name": "Speedy protein E15", "gene_name": "SPDYE15", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MGQILGKIMMSHQPQPQEERSPQRSTSGYPLQEVVDDEVLGPSAPGVDPSPPRRSLGWKRKRECLDESDDEPEKELAPEPEETWVAETLCGLKMKAKRRRVSLVLPEYYEAFNRLLEDPVIKRLLAWDKDLRVSDKYLLAMVIAYFSRAGLPSWQYQRIHFFLALYLANDMEEDDEAPKQNIFYFLYEETRSHIPLLSELWFQLCRYMNPRARKNCSQIALFRKYRFHFFCSMRCRAWVSLEELEEIQAYDPEHWVWARDRAHLS", "length": 265 }, "evidence": [ { "id": "G3MZM9", "url": "https://omabrowser.org/oma/group/G3MZM9/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "P0DW11-1", "protein_name": "TATA-box-binding protein-associated factor 11-like protein 6", "gene_name": "TAF11L6", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "METGRQTGVSAEMLAMPRGLKGSKKDGIPEDLDGNLEAPRDQEGELRSEDVMDLTEGDSEASASAPPAAKRRKTHTKGKKESKPTVDAEEAQRMTTLLSAMSEEQLSRYEVCRRSAFPRARVAGLMRAITGSSVSENAAIAMAGIAKLFVGEVVEEALDVCEMWGETPPLQPKHLREAVRRLKPKGLFPNSNCKRIMF", "length": 198 }, "evidence": [ { "id": "G3MZM9", "url": "https://omabrowser.org/oma/group/G3MZM9/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "P0DW12-1", "protein_name": "TATA-box-binding protein-associated factor 11-like protein 7", "gene_name": "TAF11L7", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "METGRQTGVSAEMLAMPRGLKGSKKDGIPEDLDGNLEAPRDQEGELRSEDVMDLTEGDSEASASAPPAAKRRKTHTKGKKESKPTVDAEEAQRMTTLLSAMSEEQLSRYEVCRRSAFPRARVAGLMRAITGSSVSENAAIAMAGIAKLFVGEVVEEALDVCEMWGETPPLQPKHLREAVRRLKPKGLFPNSNCKRIMF", "length": 198 }, "evidence": [ { "id": "G3MZM9", "url": "https://omabrowser.org/oma/group/G3MZM9/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "P0DW13-1", "protein_name": "TATA-box-binding protein-associated factor 11-like protein 8", "gene_name": "TAF11L8", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "METGRQTGVSAEMLAMPRGLKGSKKDGIPEDLDGNLEAPRDQEGELRSEDVMDLTEGDSEASASAPPAAKRRKTHTKGKKESKPTVDAEEAQRMTTLLSAMSEEQLSRYEVCRRSAFPRARVAGLMRAITGSSVSENAAIAMAGIAKLFVGEVVEEALDVCEMWGETPPLQPKHLREAVRRLKPKGLFPNSNCKRIMF", "length": 198 }, "evidence": [ { "id": "G3MZM9", "url": "https://omabrowser.org/oma/group/G3MZM9/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "P0DW14-1", "protein_name": "TATA-box-binding protein-associated factor 11-like protein 10", "gene_name": "TAF11L10", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "METGRQTGVSAEMLAMPRGLKGSKKDGIPEDLDGNLEAPRDQEGELRSEDVMDLTEGDSEASASAPPAAKRRKTHTKGKKESKPTVDAEEAQRMTTLLSAMSEEQLSRYEVCRRSAFPRARVAGLMRAITGSSVSENAAIAMAGIAKLFVGEVVEEALDVCEMWGETPPLQPKHLREAVRRLKPKGLFPNSNCKRIMF", "length": 198 }, "evidence": [ { "id": "G3MZM9", "url": "https://omabrowser.org/oma/group/G3MZM9/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "P11588-1", "protein_name": "Major urinary protein 1", "gene_name": "Mup1", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MKMLLLLCLGLTLVCVHAEEASSTGRNFNVEKINGEWHTIILASDKREKIEDNGNFRLFLEQIHVLENSLVLKFHTVRDEECSELSMVADKTEKAGEYSVTYDGFNTFTIPKTDYDNFLMAHLINEKDGETFQLMGLYGREPDLSSDIKERFAQLCEKHGILRENIIDLSNANRCLQARE", "length": 180 }, "evidence": [ { "id": "G3MZM9", "url": "https://omabrowser.org/oma/group/G3MZM9/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "P11589-1", "protein_name": "Major urinary protein 2", "gene_name": "Mup2", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MKMLLLLCLGLTLVCVHAEEASSTGRNFNVEKINGEWHTIILASDKREKIEDNGNFRLFLEQIHVLEKSLVLKFHTVRDEECSELSMVADKTEKAGEYSVTYDGFNTFTIPKTDYDNFLMAHLINEKDGETFQLMGLYGREPDLSSDIKERFAKLCEEHGILRENIIDLSNANRCLQARE", "length": 180 }, "evidence": [ { "id": "G3MZM9", "url": "https://omabrowser.org/oma/group/G3MZM9/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "P13255-1", "protein_name": "Glycine N-methyltransferase", "gene_name": "Gnmt", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MVDSVYRTRSLGVAAEGIPDQYADGEAARVWQLYIGDTRSRTAEYKAWLLGLLRQHGCHRVLDVACGTGVDSIMLVEEGFSVTSVDASDKMLKYALKERWNRRKEPAFDKWVIEEANWLTLDKDVPAGDGFDAVICLGNSFAHLPDSKGDQSEHRLALKNIASMVRPGGLLVIDHRNYDYILSTGCAPPGKNIYYKSDLTKDITTSVLTVNNKAHMVTLDYTVQVPGAGRDGAPGFSKFRLSYYPHCLASFTELVQEAFGGRCQHSVLGDFKPYRPGQAYVPCYFIHVLKKTG", "length": 293 }, "evidence": [ { "id": "G3MZM9", "url": "https://omabrowser.org/oma/group/G3MZM9/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "P13675-1", "protein_name": "Y-linked testis-specific protein 1", "gene_name": "Ssty1", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MSSLMKKRRRKSSSNTLRNIVSCRISHSWKEGNEPVTQWKAIVLDQLPTNPSLYFVKYDGIDSIYVLELYSDDRILNLKVLPPIVVFPQVRDAHLARALVGRAVQHKFERKDGSEVNWRGVVLAQVPIMKDLFYITYKKDPALYAYQLLDDYKEGNLHMIPDTPPAEERSGDDSDVLIGNWVEYTRKDGSKKFGKVVYQVLANPSVYFIKFHGDIHIYVYTMVPKILEVEKS", "length": 232 }, "evidence": [ { "id": "G3MZM9", "url": "https://omabrowser.org/oma/group/G3MZM9/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "P15515-1", "protein_name": "Histatin-1", "gene_name": "HTN1", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MKFFVFALVLALMISMISADSHEKRHHGYRRKFHEKHHSHREFPFYGDYGSNYLYDN", "length": 57 }, "evidence": [ { "id": "G3MZM9", "url": "https://omabrowser.org/oma/group/G3MZM9/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "P16374-1", "protein_name": "Zinc finger protein 60", "gene_name": "Zfp60", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MANSSSQHMVCGSVTFRDVAVDFSQEEWACLDATQKVLYRNIMLETYSNLVAVVGRCIPKPDLIVLLEPEKEPWMAVKKETGRPSQGLETGFEAENRSPKNHVYNKKLPKQTIQQLSKTSDVQGVSVSNGPGYSVIKEPQNYQEGDANRNITNKKEMSTYTSKTLAHNKEKPYKCKDCGKCFGCKSNLHQHESIHTGEKPYECKDCGKTFRLPQMLSRHQKSHSDERPFECNICGKSFHLPTLLQYHKNIHTGLKPFECEECGKSFKSFNRISTLFQHRTIHAGMKPYKCNVCGKAFNRRSNLLQHQKIHSEDRPFHCKVCGKAFTVLAQLTRHENIHTEDKSFECKQCGKIFSNGSYLLRHYDTHTNEKPFECNICGKAFRLHLYLSEHQKTHTDEKPFKCKLCESAFRRKYQLSEHQRIHTDGKPYQCKDCWEFFRRRSNFIEHQSIHTGKKPFECKDCGKVFRLNIHLIRHQRFHSDEKPFECKECGKAFHFSSQLNNHKTSHTGQTPFECKECGKSFKRVSSLVEHRIIHSGVKPYKCNACGRAFNRRSNLMQHEKIHSDERPFECKDCGKAFTVLAQLTRHQTIHNGKKSYECEQCGSAFRLPYQLTQHQRIHYDVKPFQCKECGRAFVRSTGLRIHERIHTGEKPFQCKECGEAFQYHYQFLGHFRIHTGKNPYECSECGKYFTYGRDLKVHQSIHNLEKP", "length": 707 }, "evidence": [ { "id": "G3MZM9", "url": "https://omabrowser.org/oma/group/G3MZM9/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "P20816-1", "protein_name": "Cytochrome P450 4A2", "gene_name": "Cyp4a2", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MGFSVFSPTRSLDGVSGFFQGAFLLSLFLVLFKAVQFYLRRQWLLKALEKFPSTPSHWLWGHNLKDREFQQVLTWVEKFPGACLQWLSGSTARVLLYDPDYVKVVLGRSDPKPYQSLAPWIGYGLLLLNGKKWFQHRRMLTPAFHYDILKPYVKIMADSVSIMLDKWEKLDDQDHPLEIFHYVSLMTLDTVMKCAFSHQGSVQLDVNSRSYTKAVEDLNNLIFFRVRSAFYGNSIIYNMSSDGRLSRRACQIAHEHTDGVIKTRKAQLQNEEELQKARKKRHLDFLDILLFAKMEDGKSLSDEDLRAEVDTFMFEGHDTTASGISWVFYALATHPEHQERCREEVQSILGDGTSVTWDHLDQMPYTTMCIKEALRLYSPVPSVSRELSSPVTFPDGRSIPKGIRVTILIYGLHHNPSYWPNPKVFDPSRFSPDSPRHSHAYLPFSGGARNCIGKQFAMNELKVAVALTLLRFELLPDPTRIPVPMPRLVLKSKNGIHLRLKKLR", "length": 504 }, "evidence": [ { "id": "G3MZM9", "url": "https://omabrowser.org/oma/group/G3MZM9/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "P21571-1", "protein_name": "ATP synthase peripheral stalk subunit F6, mitochondrial", "gene_name": "Atp5pf", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MTVQRIFRLSSVLRSAVSVHLRRNIGVTAVAFNKELDPVQKLFLDKIREYKAKRLASGGPVDTGPEYQQEVDRELFKLKQMYGKGEMDKFPTFNFEDPKFEVLDKPQS", "length": 108 }, "evidence": [ { "id": "G3MZM9", "url": "https://omabrowser.org/oma/group/G3MZM9/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "P22237-1", "protein_name": "NADH-ubiquinone oxidoreductase subunit 9", "gene_name": "nad9", "tax_id": 44689, "organism": "Dictyostelium discoideum", "sequence": { "sequence": "MKDYKNELKVKINLGEHLRLSIPGLVKKIMYKTHYLEIQVEKEKMLTVLKYLKEASKYQCNMLLDIVCVDCLNIEEIKIGRFKLIYVLNSIYNNTRVHLSTYVENNGIIETTSGLFESSVWLEREIWDMFGIYFEKHPDLRRILTDYGFVGYPLKKDFPITGYLEVYYDVNDKKIIYKPIELMQEYRNYNFGAVWGDYERKVYLENIIK", "length": 209 }, "evidence": [ { "id": "G3MZM9", "url": "https://omabrowser.org/oma/group/G3MZM9/", "database": "OMA" } ], "glygen_name": "Cellular slime mold", "common_name": "Social amoeba" }, { "uniprot_canonical_ac": "P22283-1", "protein_name": "Cystatin-related protein 2", "gene_name": "Crp2", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MYKTLCGTQLLLAIFVLFLNFSHATAKGTRGPMEIFKKNFMEKNKLNDVYDIFKFLYNKFSHDTYLSNIKNQSFTMNTWGFGEIEVVKTKCRKIDSDFYKCSFQWEFCNIKRTPGVTIYYITLPGSVRCRKLLSKLVNCPFEEQTEQLKREICYFQLYPDYIEQNIRSVRFNCYTK", "length": 176 }, "evidence": [ { "id": "G3MZM9", "url": "https://omabrowser.org/oma/group/G3MZM9/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "P23266-1", "protein_name": "Olfactory receptor 1f45", "gene_name": "Or1f45", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MSSTNQSSVTEFLLLGLSRQPQQQQLLFLLFLIMYLATVLGNLLIILAIGTDSRLHTPMYFFLSNLSFVDVCFSSTTVPKVLANHILGSQAISFSGCLTQLYFLAVFGNMDNFLLAVMSYDRFVAICHPLHYTTKMTRQLCVLLVVGSWVVANMNCLLHILLMARLSFCADNMIPHFFCDGTPLLKLSCSDTHLNELMILTEGAVVMVTPFVCILISYIHITCAVLRVSSPRGGWKSFSTCGSHLAVVCLFYGTVIAVYFNPSSSHLAGRDMAAAVMYAVVTPMLNPFIYSLRNSDMKAALRKVLAMRFPSKQ", "length": 313 }, "evidence": [ { "id": "G3MZM9", "url": "https://omabrowser.org/oma/group/G3MZM9/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "P24049-1", "protein_name": "Large ribosomal subunit protein uL22", "gene_name": "Rpl17", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MVRYSLDPENPTKSCKSRGSNLRVHFKNTRETAQAIKGMHIRKATKYLKDVTLKKQCVPFRRYNGGVGRCAQAKQWGWTQGRWPKKSAEFLLHMLKNAESNAELKGLDVDSLVIEHIQVNKAPKMRRRTYRAHGRINPYMSSPCHIEMILTEKEQIVPKPEEEVAQKKKISQKKLKKQKLMARE", "length": 184 }, "evidence": [ { "id": "G3MZM9", "url": "https://omabrowser.org/oma/group/G3MZM9/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "P24868-1", "protein_name": "G2/mitotic-specific cyclin-1", "gene_name": "CLB1", "tax_id": 559292, "organism": "Saccharomyces cerevisiae S288C", "sequence": { "sequence": "MSRSLLVENSRTINSNEEKGVNESQYILQKRNVPRTILGNVTNNANILQEISMNRKIGMKNFSKLNNFFPLKDDVSRADDFTSSFNDSRQGVKQEVLNNKENIPEYGYSEQEKQQCSNDDSFHTNSTALSCNRLIYSENKSISTQMEWQKKIMREDSKKKRPISTLVEQDDQKKFKLHELTTEEEVLEEYEWDDLDEEDCDDPLMVSEEVNDIFDYLHHLEIITLPNKANLYKHKNIKQNRDILVNWIIKIHNKFGLLPETLYLAINIMDRFLCEEVVQLNRLQLVGTSCLFIASKYEEIYSPSIKHFAYETDGACSVEDIKEGERFILEKLDFQISFANPMNFLRRISKADDYDIQSRTLAKFLMEISIVDFKFIGILPSLCASAAMFLSRKMLGKGTWDGNLIHYSGGYTKAKLYPVCQLLMDYLVGSTIHDEFLKKYQSRRFLKASIISIEWALKVRKNGYDIMTLHE", "length": 471 }, "evidence": [ { "id": "G3MZM9", "url": "https://omabrowser.org/oma/group/G3MZM9/", "database": "OMA" } ], "glygen_name": "Yeast", "common_name": "Baker's yeast" }, { "uniprot_canonical_ac": "P25389-1", "protein_name": "Probable serine/threonine-protein kinase KCC4", "gene_name": "KCC4", "tax_id": 559292, "organism": "Saccharomyces cerevisiae S288C", "sequence": { "sequence": "MTVANTETHSAAKPSSTIGPWKLGETLGFGSTGKVQLAQHERTGHRTAVKVISKSIFNNNGNHSNDDSVLPYNIEREIVIMKLLSHPNVLSLYDVWETNNNLYLILEYAEKGELFNLLVDHGPLPEREAINCFRQIIIGISYCHALGIVHRDLKPENLLLDSFYNIKIADFGMAALQTDADLLETSCGSPHYAAPEIVSGLPYEGFASDVWSCGVILFALLTGRLPFDEENGNVRDLLLKVQKGQFEMPNDTEISRDAQDLIGKILVVDPRQRIKIRDILSHPLLKKYQTIKDSKSIKDLPRENTYLYPLADSNNHTSASIDDSILQNLVVLWHGRHADDIVSKLKENGTNKEKILYALLYRFKLDSVRGSNKKNRNKIKKTKKNKRSSTLSSSSSLLLNNRSIQSTPRRRTSKRHSREFSSSRKRSSFLLSSNPTDSSPIPLRSSKRITHINVASANTQATPSGVPNPHKRNSKKRSSKRLSYMPNTKRSSLTSKSLSNFTNLIDDDDWEYIEKDAKRTSSNFATLIDEIFEPEKFELAKREKAELQRKVQEAKRQSVNAQKINEDEFGSEVSDGMKELKKINDKVSSPLINYEFSQQELLQDIDTLLTNRYQLSSYTRPISRLDPGLTPVTETLPNNLKEKTALLQDTEKKIIETIRRSKFLGSLLNVRGGLSPGKSELAPIEESPIVSTTPLIYNDRMEPRRISDVEVPHFTRKSKHFTTANNRRSVLSLYAKDSIKDLNEFLIKEDPDLPPQGSTDNESRSEDPEIAESITDSRNIQYDEDDSKDGDNVNNDNILSDFPQGVGISQEYDMKDKNPNQSPISKSAEPTLVVKLPSLSSFQGKNASGLGLYQREPSKVTLPSLTSNNSSVGENIEDGAEKGTESEKIAASLSDDDLKEDNDKKDNDTVNAPTTVKKPPNSVLLKKFSKGKILELEIHAKIPEKRLYEGLHKLLEGWKQYGLKNLVFNITNMIITGKLVNDSILFLRSTLFEIMVLPNGDGRSLIKFNKKTGSTKTLTKLATEIQIILQKEGVLDK", "length": 1037 }, "evidence": [ { "id": "G3MZM9", "url": "https://omabrowser.org/oma/group/G3MZM9/", "database": "OMA" } ], "glygen_name": "Yeast", "common_name": "Baker's yeast" }, { "uniprot_canonical_ac": "P28312-1", "protein_name": "Alpha-defensin 5", "gene_name": "Defa5", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MKTFVLLSALVLLAFQVQADPIHKTDEETNTEEQPGEEDQAVSISFGGQEGSALHEELSKKLICYCRIRGCKRRERVFGTCRNLFLTFVFCCS", "length": 93 }, "evidence": [ { "id": "G3MZM9", "url": "https://omabrowser.org/oma/group/G3MZM9/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "P28742-1", "protein_name": "Kinesin-like protein KIP1", "gene_name": "KIP1", "tax_id": 559292, "organism": "Saccharomyces cerevisiae S288C", "sequence": { "sequence": "MARSSLPNRRTAQFEANKRRTIAHAPSPSLSNGMHTLTPPTCNNGAATSDSNIHVYVRCRSRNKREIEEKSSVVISTLGPQGKEIILSNGSHQSYSSSKKTYQFDQVFGAESDQETVFNATAKNYIKEMLHGYNCTIFAYGQTGTGKTYTMSGDINILGDVQSTDNLLLGEHAGIIPRVLVDLFKELSSLNKEYSVKISFLELYNENLKDLLSDSEDDDPAVNDPKRQIRIFDNNNNNSSIMVKGMQEIFINSAHEGLNLLMQGSLKRKVAATKCNDLSSRSHTVFTITTNIVEQDSKDHGQNKNFVKIGKLNLVDLAGSENINRSGAENKRAQEAGLINKSLLTLGRVINALVDHSNHIPYRESKLTRLLQDSLGGMTKTCIIATISPAKISMEETASTLEYATRAKSIKNTPQVNQSLSKDTCLKDYIQEIEKLRNDLKNSRNKQGIFITQDQLDLYESNSILIDEQNLKIHNLREQIKKFKENYLNQLDINNLLQSEKEKLIAIIQNFNVDFSNFYSEIQKIHHTNLELMNEVIQQRDFSLENSQKQYNTNQNMQLKISQQVLQTLNTLQGSLNNYNSKCSEVIKGVTEELTRNVNTHKAKHDSTLKSLLNITTNLLMNQMNELVRSISTSLEIFQSDSTSHYRKDLNEIYQSHQQFLKNLQNDIKSCLDSIGSSILTSINEISQNCTTNLNSMNVLIENQQSGSSKLIKEQDLEIKKLKNDLINERRISNQFNQQLAEMKRYFQDHVSRTRSEFHDELNKCIDNLKDKQSKLDQDIWQKTASIFNETDIVVNKIHSDSIASLAHNAENTLKTVSQNNESFTNDLISLSRGMNMDISSKLRSLPINEFLNKISQTICETCGDDNTIASNPVLTSIKKFQNIICSDIALTNEKIMSLIDEIQSQIETISNENNINLIAINENFNSLCNFILTDYDENIMQISKTQDEVLSEHCEKLQSLKILGMDIFTAHSIEKPLHEHTRPEASVIKALPLLDYPKQFQIYRDAENKSKDDTSNSRTCIPNLSTNENFPLSQFSPKTPVPVPDQPLPKVLIPKSINSAKSNRSKTLPNTEGTGRESQNNLKRRFTTEPILKGEETENNDILQNKKLHQ", "length": 1111 }, "evidence": [ { "id": "G3MZM9", "url": "https://omabrowser.org/oma/group/G3MZM9/", "database": "OMA" } ], "glygen_name": "Yeast", "common_name": "Baker's yeast" }, { "uniprot_canonical_ac": "P29314-1", "protein_name": "Small ribosomal subunit protein uS4", "gene_name": "Rps9", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MPVARSWVCRKTYVTPRRPFEKSRLDQELKLIGEYGLRNKREVWRVKFTLAKIRKAARELLTLDEKDPRRLFEGNALLRRLVRIGVLDEGKMKLDYILGLKIEDFLERRLQTQVFKLGLAKSIHHARVLIRQRHIRVRKQVVNIPSFIVRLDSQKHIDFSLRSPYGGGRPGRVKRKNAKKGQGGAGAGDDEEED", "length": 194 }, "evidence": [ { "id": "G3MZM9", "url": "https://omabrowser.org/oma/group/G3MZM9/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "P33579-1", "protein_name": "Prolactin-8A5", "gene_name": "Prl8a5", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MELALSQPSFFGTLLMLVVSNLLLWEKAASIPACMVEDGGCWDPLREAFNSATQRAETLRNLSDQLYVEFFQNQFSSRQFADLSSQLIRKDETVLKAGTYCHSNRAKPKSRGVNIDIEEYLKMSINFCGFMDQPLFHLVIELSAMEGVPETILSKAKDLEENNRQLLDDLRWILTKVFPTAEIKEEFPSWDYLSFLKSSNKNHKFLAIFNLSSCLDYDTQVHYTLSQILNCLITGKDC", "length": 238 }, "evidence": [ { "id": "G3MZM9", "url": "https://omabrowser.org/oma/group/G3MZM9/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "P36006-1", "protein_name": "Myosin-3", "gene_name": "MYO3", "tax_id": 559292, "organism": "Saccharomyces cerevisiae S288C", "sequence": { "sequence": "MAVIKKGARRKDVKEPKKRSAKIKKATFDANKKKEVGISDLTLLSKISDESINENLKKRFKNGIIYTYIGHVLISVNPFRDLGIYTNAVLESYKGKNRLEVPPHVFAIAESMYYNLKSYNENQCVIISGESGAGKTEAAKRIMQYIAAASNSHSESIGKIKDMVLATNPLLESFGCAKTLRNNNSSRHGKYLEIKFNSQFEPCAGNITNYLLEKQRVVGQIKNERNFHIFYQFTKGASDTYKQMFGVQMPEQYIYTAAAGCTTADTIDDVKDYEGTLEAMRTIGLVQEEQDQIFRMLAAILWIGNISFIENEEGNAQVGDTSVTDFVAYLLQVDASLLVKCLVERIMQTSHGMKRGSVYHVPLNPVQATAVRDALAKAIYNNLFDWIVDRVNVSLQAFPGADKSIGILDIYGFEIFEHNSFEQICINYVNEKLQQIFIQLTLKAEQETYEREKIKWTPIKYFDNKVVCDLIEAKNPPGILAAMNDSIATAHADSNAADQAFAQRLNLFNSNPYFELRANKFVIKHYAGDVTYDINGITDKNKDQLQKDLIELIGTTTNTFLSTIFPDDVDKDSKRRPPTAGDKIIKSANELVETLSKAEPSYIRTIKPNQTKSPNDYDDHQVLHQVKYLGLQENVRIRRAGFAYRQTFEKFVERFYLLSPDCSYAGDYTWDGDTLEAVKLILRDAMIPEKEFQLGVTSVFIKTPESLFALEDMRDKYWYNMAARIQRAWRRFLQRRIDAAIKIQRTIREKKGGNKYVKLRDYGTKLLAGKKERRSMSLLGYRAFMGDYLSCNESKTKGSYIRRQVGIKDKVVFSIKGECLHSKFGRSAQRLKKVFILTKKTFYIIGQTREQNAMKYTQDYKIDVGKIKQVSLTNLQDDWMGVILVNSTQSDPLINTPFKTELMTRLKKLNEKIMIKVGPTIEYHKQPNKLHTVRSKISDSAPKYGDIYKSSTIYVRRGHPANSKSNKKPKNPGGLSGKPIKSKKSKHKSTHKHTHSHRSHRDAAKKQPLPSQKPVNPLSLAATAAQAAYNPKPDKTVPIKSSAIPAAKVSSKHSSKPSSKEKVAVKKASSSHKSSSAKQNQVSMPPSKGVEKNKEPLKETTATATANIPIPPPPPPMGQPKDPKFEAAYDFPGSGSSSELPLKKGDIVFISRDEPSGWSLAKLLDGSKEGWVPTAYMTPYKDTRNTVPVAATGAVNDVTNQKSSQIDNTISSAQEGVQFGSATVGPTSDNQSNPVGTFSDGLASALAARANKMRAESADDDDNDDGDDDDDW", "length": 1272 }, "evidence": [ { "id": "G3MZM9", "url": "https://omabrowser.org/oma/group/G3MZM9/", "database": "OMA" } ], "glygen_name": "Yeast", "common_name": "Baker's yeast" }, { "uniprot_canonical_ac": "P36046-1", "protein_name": "Mitochondrial intermembrane space import and assembly protein 40", "gene_name": "MIA40", "tax_id": 559292, "organism": "Saccharomyces cerevisiae S288C", "sequence": { "sequence": "MLRNLVVRNACRNRPSIQVARGLCRHQTRRLMASSPQFGRNSNQEKTAGFIMGILSMAGALYFIAPNRKPLFASRKVESDKTAEEELSSGGEQSPENEDDNNSKSDENGDDNDSKNDETEAGPQLGGDKIGASKVAEDGELVVLAEEDNKSSEDKDTDESKVSTKDDEQSNEDNATANNQKDENISSENSEENTSDKTLDNNAGSSEKKDPEHSDDEKSQQGQSDDKTTTEDNNGEEESSKKTVSDSENSAKQSESSDEEKEELRKQEEKQMGPTEEEVQHEGAYNPDTGEINWDCPCLGGMAHGPCGEEFKSAFSCFVYSEAEPKGIDCVEKFQHMQDCFRKYPEHYAEQLKETSDDEEPQDKVKVNTIESAPNVSSAKENAAKKAEQSDVKKEPLNEESKP", "length": 403 }, "evidence": [ { "id": "G3MZM9", "url": "https://omabrowser.org/oma/group/G3MZM9/", "database": "OMA" } ], "glygen_name": "Yeast", "common_name": "Baker's yeast" }, { "uniprot_canonical_ac": "P37106-1", "protein_name": "Signal recognition particle subunit SRP54 1", "gene_name": "SRP-54A", "tax_id": 3702, "organism": "Arabidopsis thaliana", "sequence": { "sequence": "MVLAELGGRITRAIQQMNNVTIIDEKVLNDFLNEITRALLQSDVSFGLVEKMQTNIKKIVNLDDLAAGHNKRLIIEQAIFKELCRMLDPGKPAFAPKKAKPSVVMFVGLQGAGKTTTCTKYAYYHQKKGYKAALVCADTFRAGAFDQLKQNATKAKIPFYGSYTESDPVKIAVEGVDRFKKEKCDLIIVDTSGRHKQAASLFEEMRQVAEATEPDLVIFVMDSSIGQAAFEQAEAFKETVSVGAVIITKMDGHAKGGGALSAVAATKSPVIFIGTGEHMDEFEVFDVKPFVSRLLGKGDWSGLVDKLQEVVPKDLQNELVENLSQGNFTLRSMYDQFQCSLRIPLNQLFSMLPGISAEMMPKGHGEESRVKMKRYMTMMDSMTNKELDSPNPKIFNESRIMRIARGSGRLVREVMEMLEEYKRIAKTMKGIKIPKNGDMSKVIPPQMLKQMGGMSGLQSLMKQMGSAKDMMGMFGGGGK", "length": 479 }, "evidence": [ { "id": "G3MZM9", "url": "https://omabrowser.org/oma/group/G3MZM9/", "database": "OMA" } ], "glygen_name": "Arabidopsis", "common_name": "Mouse-ear cress" }, { "uniprot_canonical_ac": "P38150-1", "protein_name": "Inactive deaminase YBR284W", "gene_name": "", "tax_id": 559292, "organism": "Saccharomyces cerevisiae S288C", "sequence": { "sequence": "MVQNNESVFFVECDSYKESPSTSPIRLDDLDGNDAVSDQGLAFDGDVGITSQARVRNPRAQIFEDSNTDVVLHLDDLDMVPLNTKFDMQMEMGSPMAMPAETPPPVEPLKTKDLAYSSLAHLPSYFFEQTHFRIDRKCLLEMSKLRRNYLTISKQDALSCPQLHSRVAGGYLKPVKEKLFGIRHFLDLEESNTVNLLQDGNYMTELFNSQINIPTFKEFREDFEWCLKIIRDRSLSRFSEKRLQYLVNKFPVFQHLHSKEEMRQSKKVPHKDFYNCRKIDLNLLLSGCFSQWQLTEFIWTKLRKEPDRVIHQAFNGSHITLSQLFKVNFEETGQFFNGLKIIDDSFLEWYKVIYLAKYHLVNDEMEIHTGSHGKQLRYYLIAKTFLEFDNYINGEYLAELLKTFLIKPQEESKYQLCQLSVDFQFYLHYDNSDVDNWWMVFANWLNHYNIFSNNIRWNIRISRIYPELYHTGKVKNFQEYLNLIFKPLFNAENYLHKSLGPILLKFLSQVSSIDLCIQDTDNYIWKNFTAVSCLPKDWTSGGDNPTISQYMYYVYVNLTKLNHIRQALHQNTFTLRSSCSPTSMNRTSQFSNTLNFTEHTEAILNNFLLACGGFLNAENLWNAPPSLVYLFYLSQIPMVVAPLNSIVDSKPTMLQEQAPTGLVLEPSKPYKKNPFMKFFEMGFKISLSSESILYNNSYTKEPIIEEYSVAASIYRLHSADLCELLRNSVITSGFSSTLKNKWLGVSLASHDYFVENTGFVDKWYDCKPNTSLEHNVPIIRRQYRSSTLAGEWRLIIA", "length": 797 }, "evidence": [ { "id": "G3MZM9", "url": "https://omabrowser.org/oma/group/G3MZM9/", "database": "OMA" } ], "glygen_name": "Yeast", "common_name": "Baker's yeast" }, { "uniprot_canonical_ac": "P40002-1", "protein_name": "Transcriptional regulator MIT1", "gene_name": "MIT1", "tax_id": 559292, "organism": "Saccharomyces cerevisiae S288C", "sequence": { "sequence": "MDIEPTFKGYIEDEDDALLILQATLDGKLKHIPRRPYEIERPYLIVSGSIFVFIEEISGIKRWTDGVSWSPSRISGKFLIYKELDKENAGSNANATSSGSTDSAVITDGTSGARNNPSSSKIKLPPLKNHQFDLPPTMGHSSFESEQDTSISPSNRSNLPLKYTGLVKKTISVKLKRPPFNSIENLHIVSYYSVKDIKQNCLVTPKASPFLKDVRPSQELIVAMGNTTLGNVKNNSTTTGNGPNNINNKSNSSTPLNTVISTNNNSANINAAGSNQFTSANKNYYYKNDESSGYPITQFAPALPSTTLMYTANPPYITQSPDNTNATGMNTHVNNNNNNSNNSSNSNNSNNNNNNNNNNNNNNNNNINNINNVNTNAGNGNNPNRFHNASFAYNTTGDFINPQQQGQISYPFYYTTIPINNPNYYTTQPPNPVTNASTNENQGYSTSSTQHPYYGHPTESQSASAAAGATGTPGTAENVLPVSSMQPLLHQANNNSASSATSTAPYPVYSMNVNVPYYNSSASAYKRAQENTTSNTNAEPSGATSTNSGTMLSNPAYANSQYTPSQVYYQGFPQYAMASAQNPSMYQHQHQHPLPTVYPIATPQQNIMSSGHTLSTIGSDPQHHHYQQEPNDHKNFAMGHANNNILNITNNDTMNNLNTNTSTTTQ", "length": 666 }, "evidence": [ { "id": "G3MZM9", "url": "https://omabrowser.org/oma/group/G3MZM9/", "database": "OMA" } ], "glygen_name": "Yeast", "common_name": "Baker's yeast" }, { "uniprot_canonical_ac": "P42222-1", "protein_name": "Enolase-related protein 3", "gene_name": "ERR3", "tax_id": 559292, "organism": "Saccharomyces cerevisiae S288C", "sequence": { "sequence": "MSITKVHARTVYDSRGNPTVEVEITTENGLFRAIVPSGASTGIHEAVELRDGNKSEWMGKGVTKAVSNVNSIIGPALIKSDLCVTNQKGIDELMISLDGTSNKSRLGANAILGVSLCVARAAAAQKGITLYKYIAELADARQDPFVIPVPFFNVLNGGAHAGGSLAMQEFKIAPVGAQSFAEAMRMGSEVYHHLKILAKEQYGPSAGNVGDEGGVAPDIDTAEDALDMIVKAINICGYEGRVKVGIDSAPSVFYKDGKYDLNFKEPNSDPSHWLSPAQLAEYYHSLLKKYPIISLEDPYAEDDWSSWSAFLKTVNVQIIADDLTCTNKTRIARAIEEKCANTLLLKLNQIGTLTESIEAANQAFDAGWGVMISHRSGETEDPFIADLVVGLRCGQIKSGALSRSERLAKYNELLRIEEELGDDCIYAGHRFHDGNKL", "length": 437 }, "evidence": [ { "id": "G3MZM9", "url": "https://omabrowser.org/oma/group/G3MZM9/", "database": "OMA" } ], "glygen_name": "Yeast", "common_name": "Baker's yeast" }, { "uniprot_canonical_ac": "P43356-1", "protein_name": "Melanoma-associated antigen 2", "gene_name": "MAGEA2", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MPLEQRSQHCKPEEGLEARGEALGLVGAQAPATEEQQTASSSSTLVEVTLGEVPAADSPSPPHSPQGASSFSTTINYTLWRQSDEGSSNQEEEGPRMFPDLESEFQAAISRKMVELVHFLLLKYRAREPVTKAEMLESVLRNCQDFFPVIFSKASEYLQLVFGIEVVEVVPISHLYILVTCLGLSYDGLLGDNQVMPKTGLLIIVLAIIAIEGDCAPEEKIWEELSMLEVFEGREDSVFAHPRKLLMQDLVQENYLEYRQVPGSDPACYEFLWGPRALIETSYVKVLHHTLKIGGEPHISYPPLHERALREGEE", "length": 314 }, "evidence": [ { "id": "G3MZM9", "url": "https://omabrowser.org/oma/group/G3MZM9/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "P43357-1", "protein_name": "Melanoma-associated antigen 3", "gene_name": "MAGEA3", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MPLEQRSQHCKPEEGLEARGEALGLVGAQAPATEEQEAASSSSTLVEVTLGEVPAAESPDPPQSPQGASSLPTTMNYPLWSQSYEDSSNQEEEGPSTFPDLESEFQAALSRKVAELVHFLLLKYRAREPVTKAEMLGSVVGNWQYFFPVIFSKASSSLQLVFGIELMEVDPIGHLYIFATCLGLSYDGLLGDNQIMPKAGLLIIVLAIIAREGDCAPEEKIWEELSVLEVFEGREDSILGDPKKLLTQHFVQENYLEYRQVPGSDPACYEFLWGPRALVETSYVKVLHHMVKISGGPHISYPPLHEWVLREGEE", "length": 314 }, "evidence": [ { "id": "G3MZM9", "url": "https://omabrowser.org/oma/group/G3MZM9/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "P43537-1", "protein_name": "Uncharacterized membrane protein YFL067W", "gene_name": "", "tax_id": 559292, "organism": "Saccharomyces cerevisiae S288C", "sequence": { "sequence": "MESIILSIAIFIGVLLGTSVGAGSGSSISPDVDAGSGSRTSPDVDAGSGSRISAGVGTFSGSSTSPDVDAGSGSSTSPDVGAGSGSSISAGVGSRIGTGIGSRIGTGIGTGIGSRISTSIGSRISPDVGTSSGNRISTGVSTGISTTMNARVAVLITAAILSAPVTAIALLEARR", "length": 175 }, "evidence": [ { "id": "G3MZM9", "url": "https://omabrowser.org/oma/group/G3MZM9/", "database": "OMA" } ], "glygen_name": "Yeast", "common_name": "Baker's yeast" }, { "uniprot_canonical_ac": "P46162-1", "protein_name": "Beta-defensin 4", "gene_name": "DEFB4", "tax_id": 9913, "organism": "Bos taurus", "sequence": { "sequence": "MRLHHLLLAVLFLVLSAGSGFTQRVRNPQSCRWNMGVCIPFLCRVGMRQIGTCFGPRVPCCRR", "length": 63 }, "evidence": [ { "id": "G3MZM9", "url": "https://omabrowser.org/oma/group/G3MZM9/", "database": "OMA" } ], "glygen_name": "Bovine", "common_name": "Bovine" }, { "uniprot_canonical_ac": "P46169-1", "protein_name": "Beta-defensin 11", "gene_name": "DEFB11", "tax_id": 9913, "organism": "Bos taurus", "sequence": { "sequence": "MRLHHLLLALLFLVLSAGSGISGPLSCRRNGGVCIPIRCPGPMRQIGTCFGRPVKCCRSW", "length": 60 }, "evidence": [ { "id": "G3MZM9", "url": "https://omabrowser.org/oma/group/G3MZM9/", "database": "OMA" } ], "glygen_name": "Bovine", "common_name": "Bovine" }, { "uniprot_canonical_ac": "P47102-1", "protein_name": "ARF guanine-nucleotide exchange factor 1", "gene_name": "GEA1", "tax_id": 559292, "organism": "Saccharomyces cerevisiae S288C", "sequence": { "sequence": "MHDVPMETVLAVNPATMIVKECINLCSAMNKQSRDKSQTSVAALLGGGSDIFLSQSDSFVDSFHNLPTSSYHDPLISGLVQLRLKINDLKGLDSLNALELLKPFLEIVSASSVSGYTTSLALDSLQKVFTLKIINKTFNDIQIAVRETVVALTHCRFEASKQISDDSVLLKVVTLLRDIITSSFGDYLSDTIIYDVLQTTLSLACNTQRSEVLRKTAEVTIAGITVKLFTKLKLLDPPTKTEKYINDESYTDNNLKDDIIGTTTSDNDLSSTDDDSAVADDNKNEKPVQQVIREQENDEETAEKAENVEPNYGITVIKDYLGLLLSLVMPENRMKHTTSAMKLSLQLINAAIEISGDKFPLYPRLFSLISDPIFKSVLFIIQSSTQYSLLQATLQLFTSLVVILGDYLPMQIELTLRRIFEILEDTTISGDVSKQKPPAIRELIIEQLSILWIHSPAFFLQLFVNFDCNLDRSDLSIDFIKELTKFSLPAAAVNTSNNIPPICLEGVLSLIENIYNDLQRFDRAEFVKNQKEIDILKQRDRKTEFILCVETFNEKAKKGIQMLIEKGFIDSDSNRDIASFLFLNNGRLNKKTIGLLLCDPKKTSLLKEFIDLFDFKGLRVDEAIRILLTKFRLPGESQQIERIVEAFSSKYSADQSNDKVELEDKKAGKNGSESMTEDDIIHVQPDADSVFVLSYSIIMLNTDSHNPQVKDHMTFDDYSNNLRGCYNGKDFPRWYLHKIYTSIKVKEIVMPEEHHGNERWFEDAWNNLISSTSVMTEMQRDFTNPISKLAQIDILQYEKAIFSNVRDIILKTLFKIFTVASSDQISLRILDAISKCTFINYYFSFDQSYNDTVLHLGEMTTLAQSSAKAVELDVDSIPLVEIFVEDTGSKISVSNQSIRLGQNFKAQLCTVLYFQIIKEISDPSIVSTRLWNQIVQLILKLFENLLMEPNLPFFTNFHSLLKLPELPLPDPDISIRKAKMSRSLLSTFASYLKGDEEPSEEDIDFSIKAFECVKASHPLSSVFENNQLVSPKMIETLLSSLVIEKTSENSPYFEQELLFLLEISIILISEASYGQEFGALIADHMINISNLDGLSKEAIARLASYKMFLVSRFDNPRDILSDLIEHDFLVKNEIFNTKYYESEWGKQVINDLFTHLNDVKYNERALKNVKFWNFLRILISAKDRQFAVYTFLEKYIQNGDIFVDDGNFMNILSLLDEMSCAGAVGTKWEQNYENSVEDGCEAPESNPYRSIIDLSSRSINITADLLSTVGRSNSALNKNEIIAAIQGLAHQCLNPCDELGMQALQALENILLSRASQLRTEKVAVDNLLETGLLPIFELDEIQDVKMKRITSILSVLSKIFLGQLVEGVTSNETFLRVLNVFNKYVDDPTVERQLQELIISKREIEKE", "length": 1408 }, "evidence": [ { "id": "G3MZM9", "url": "https://omabrowser.org/oma/group/G3MZM9/", "database": "OMA" } ], "glygen_name": "Yeast", "common_name": "Baker's yeast" }, { "uniprot_canonical_ac": "P53563-1", "protein_name": "Bcl-2-like protein 1", "gene_name": "Bcl2l1", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MSQSNRELVVDFLSYKLSQKGYSWSQFSDVEENRTEAPEETEPERETPSAINGNPSWHLADSPAVNGATGHSSSLDAREVIPMAAVKQALREAGDEFELRYRRAFSDLTSQLHITPGTAYQSFEQVVNELFRDGVNWGRIVAFFSFGGALCVESVDKEMQVLVSRIASWMATYLNDHLEPWIQENGGWDTFVDLYGNNAAAESRKGQERFNRWFLTGMTVAGVVLLGSLFSRK", "length": 233 }, "evidence": [ { "id": "G3MZM9", "url": "https://omabrowser.org/oma/group/G3MZM9/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "P56840-1", "protein_name": "Protein TCL1B1", "gene_name": "Tcl1b1", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MAAAAFDPLGPLPVYLVSVRLGIYEDEHHRVWIVANVETSHSSHGNRRRTHVTVHLWKLIPQQVIPFNPLNYDFLPTTWKLESRNIYWATDGTHWRLLDHSQLGDTEQLILMLVLG", "length": 116 }, "evidence": [ { "id": "G3MZM9", "url": "https://omabrowser.org/oma/group/G3MZM9/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "P56841-1", "protein_name": "Protein TCL1B2", "gene_name": "Tcl1b2", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MAAAGFYPPRLLPQVLISTGPGFYEDEHHRLWMVAKLETCSHSPYCNKIETCVTVHLWQMTRYPQEPAPYNPMNYNFLPMTWRLASMNTYRGTDAMHWRLLNHSQVGDTVQLILMLE", "length": 117 }, "evidence": [ { "id": "G3MZM9", "url": "https://omabrowser.org/oma/group/G3MZM9/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "P56842-1", "protein_name": "Protein TCL1B3", "gene_name": "Tcl1b3", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MADSVHFPWMPFPPRFLVCTRDDIYEDENGRQWVVAKVETSRSPYGSRIETCITVHLQHMTTIPQEPTPQQPINNNSLPTMWRLESMNTYTGTDGTYWRLLDHSQMGDTLQLILDIVICEVD", "length": 122 }, "evidence": [ { "id": "G3MZM9", "url": "https://omabrowser.org/oma/group/G3MZM9/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "P56844-1", "protein_name": "Protein TCL1B4", "gene_name": "Tcl1b4", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MADSVRFPCMPFPPCFLVCTRDDIYEDEHGRQWVAAKVETSSHSPYCSKIETCVTVHLWQMTTLFQEPSPDSLKTFNFLPRTWRLESRNTYRGADAMHWRLVNHSQFYGTEELVLMLDSR", "length": 120 }, "evidence": [ { "id": "G3MZM9", "url": "https://omabrowser.org/oma/group/G3MZM9/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "P59528-1", "protein_name": "Taste receptor type 2 member 123", "gene_name": "Tas2r123", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MFSQKINYSHLFTFSITLYVEIVTGILGHGFIALVNIMDWVKRRRISSVDQILTALALTRFIYVLSMLICILLFMLCPHLPRRSEMLSAMGIFWVVNSHFSIWLTTCLGVFYFLKIANFSNSFFLYLKWRVKKVILIIILASLIFLTLHILSLGIYDQFSIAAYVGNMSYSLTDLTQFSSTFLFSNSSNVFLITNSSHVFLPINSLFMLIPFTVSLVAFLMLIFSLWKHHKKMQVNAKQPRDVSTMAHIKALQTVFSFLLLYAIYLLFLIIGILNLGLMEKIVILIFDHISGAVFPISHSFVLILGNSKLRQASLSVLPCLRCQSKDMDTMGL", "length": 333 }, "evidence": [ { "id": "G3MZM9", "url": "https://omabrowser.org/oma/group/G3MZM9/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "P61314-1", "protein_name": "Large ribosomal subunit protein eL15", "gene_name": "Rpl15", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MGAYKYIQELWRKKQSDVMRFLLRVRCWQYRQLSALHRAPRPTRPDKARRLGYKAKQGYVIYRIRVRRGGRKRPVPKGATYGKPVHHGVNQLKFARSLQSVAEERAGRHCGALRVLNSYWVGEDSTYKFFEVILIDPFHKAIRRNPDTQWITKPVHKHREMRGLTSAGRKSRGLGKGHKFHHTIGGSRRAAWRRRNTLQLHRYR", "length": 204 }, "evidence": [ { "id": "G3MZM9", "url": "https://omabrowser.org/oma/group/G3MZM9/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "P62246-1", "protein_name": "Small ribosomal subunit protein uS8", "gene_name": "Rps15a", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MVRMNVLADALKSINNAEKRGKRQVLIRPCSKVIVRFLTVMMKHGYIGEFEIIDDHRAGKIVVNLTGRLNKCGVISPRFDVQLKDLEKWQNNLLPSRQFGFIVLTTSAGIMDHEEARRKHTGGKILGFFF", "length": 130 }, "evidence": [ { "id": "G3MZM9", "url": "https://omabrowser.org/oma/group/G3MZM9/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "P62425-1", "protein_name": "Large ribosomal subunit protein eL8", "gene_name": "Rpl7a", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MPKGKKAKGKKVAPAPAVVKKQEAKKVVNPLFEKRPKNFGIGQDIQPKRDLTRFVKWPRYIRLQRQRAILYKRLKVPPAINQFTQALDRQTATQLLKLAHKYRPETKQEKKQRLLARAEKKAAGKGDVPTKRPPVLRAGVNTVTTLVENKKAQLVVIAHDVDPIELVVFLPALCRKMGVPYCIIKGKARLGRLVHRKTCTTVAFTQVNSEDKGALAKLVEAIRTNYNDRYDEIRRHWGGNVLGPKSVARIAKLEKAKAKELATKLG", "length": 266 }, "evidence": [ { "id": "G3MZM9", "url": "https://omabrowser.org/oma/group/G3MZM9/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "P62802-1", "protein_name": "Histone H4", "gene_name": "", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MSGRGKGGKGLGKGGAKRHRKVLRDNIQGITKPAIRRLARRGGVKRISGLIYEETRGVLKVFLENVIRDAVTYTEHAKRKTVTAMDVVYALKRQGRTLYGFGG", "length": 103 }, "evidence": [ { "id": "G3MZM9", "url": "https://omabrowser.org/oma/group/G3MZM9/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "P62963-1", "protein_name": "Profilin-1", "gene_name": "Pfn1", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MAGWNAYIDSLMADGTCQDAAIVGYKDSPSVWAAVPGKTFVSITPAEVGVLVGKDRSSFFVNGLTLGGQKCSVIRDSLLQDGEFTMDLRTKSTGGAPTFNVTVTMTAKTLVLLMGKEGVHGGLINKKCYEMASHLRRSQY", "length": 140 }, "evidence": [ { "id": "G3MZM9", "url": "https://omabrowser.org/oma/group/G3MZM9/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "P62982-1", "protein_name": "Ubiquitin-ribosomal protein eS31 fusion protein", "gene_name": "Rps27a", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MQIFVKTLTGKTITLEVEPSDTIENVKAKIQDKEGIPPDQQRLIFAGKQLEDGRTLSDYNIQKESTLHLVLRLRGGAKKRKKKSYTTPKKNKHKRKKVKLAVLKYYKVDENGKISRLRRECPSDECGAGVFMGSHFDRHYCGKCCLTYCFNKPEDK", "length": 156 }, "evidence": [ { "id": "G3MZM9", "url": "https://omabrowser.org/oma/group/G3MZM9/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "P70709-1", "protein_name": "Eosinophil cationic protein", "gene_name": "Rnase3", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MGLKLLESRLCLLLSLGLVLMLASCQPPTPSQWFEIQHIYNRAYPRCNDAMRHRNRFTGHCKDINTFLHTSFASVVGVCGNRNIPCGNRTYRNCHNSRYRVSITFCNLTTPARIYTQCRYQTTRSRKFYTVGCDPRTPRDSPMYPVVPVHLDRIF", "length": 155 }, "evidence": [ { "id": "G3MZM9", "url": "https://omabrowser.org/oma/group/G3MZM9/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "P81278-1", "protein_name": "Prolactin-releasing peptide", "gene_name": "Prlh", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MALKTWLLCLLLLSLVLPGASSRAHQHSMETRTPDINPAWYTGRGIRPVGRFGRRRATPRDVTGLGQLSCLPLDGRTKFSQRG", "length": 83 }, "evidence": [ { "id": "G3MZM9", "url": "https://omabrowser.org/oma/group/G3MZM9/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "P83883-1", "protein_name": "Large ribosomal subunit protein eL42", "gene_name": "Rpl36a", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MVNVPKTRRTFCKKCGKHQPHKVTQYKKGKDSLYAQGKRRYDRKQSGYGGQTKPIFRKKAKTTKKIVLRLECVEPNCRSKRMLAIKRCKHFELGGDKKRKGQVIQF", "length": 106 }, "evidence": [ { "id": "G3MZM9", "url": "https://omabrowser.org/oma/group/G3MZM9/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "P83884-1", "protein_name": "Large ribosomal subunit protein eL42", "gene_name": "RPL36A", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MVNVPKTRRTFCKKCGKHQPHKVTQYKKGKDSLYAQGKRRYDRKQSGYGGQTKPIFRKKAKTTKKIVLRLECVEPNCRSKRMLAIKRCKHFELGGDKKRKGQVIQF", "length": 106 }, "evidence": [ { "id": "G3MZM9", "url": "https://omabrowser.org/oma/group/G3MZM9/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "P97876-1", "protein_name": "Basic leucine zipper transcriptional factor ATF-like 3", "gene_name": "Batf3", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MSQGPPAGGVLQSSVAAPGNQPQSPKDDDRKVRRREKNRVAAQRSRKKQTQKSDKLHEEHESLEQENSVLRREIAKLKEELRHLTEALKEHEKMCPLLLCPMNFVQLRPDPVASWSAHDAPDHPSFIWLGTLV", "length": 133 }, "evidence": [ { "id": "G3MZM9", "url": "https://omabrowser.org/oma/group/G3MZM9/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "Q00729-1", "protein_name": "Histone H2B type 1-A", "gene_name": "H2bc1", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MPEVSAKGTTISKKGFKKAVTKTQKKEGRKRKRCRKESYSIYIYKVLKQVHPDTGISSKAMSIMNSFVTDIFERIAGEASRLAHYNKRSTITSREIQTAVRLLLPGELAKHAVSEGTKAVTKYTSSK", "length": 127 }, "evidence": [ { "id": "G3MZM9", "url": "https://omabrowser.org/oma/group/G3MZM9/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "Q01534-1", "protein_name": "Testis-specific Y-encoded protein 1", "gene_name": "TSPY1", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MRPEGSLTYRVPERLRQGFCGVGRAAQALVCASAKEGTAFRMEAVQEGAAGVESEQAALGEEAVLLLDDIMAEVEVVAEEEGLVERREEAQRAQQAVPGPGPMTPESAPEELLAVQVELEPVNAQARKAFSRQREKMERRRKPHLDRRGAVIQSVPGFWANVIANHPQMSALITDEDEDMLSYMVSLEVGEEKHPVHLCKIMLFFRSNPYFQNKVITKEYLVNITEYRASHSTPIEWYPDYEVEAYRRRHHNSSLNFFNWFSDHNFAGSNKIAEILCKDLWRNPLQYYKRMKPPEEGTETSGDSQLLS", "length": 308 }, "evidence": [ { "id": "G3MZM9", "url": "https://omabrowser.org/oma/group/G3MZM9/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "Q03764-1", "protein_name": "Ethanolamine kinase", "gene_name": "EKI1", "tax_id": 559292, "organism": "Saccharomyces cerevisiae S288C", "sequence": { "sequence": "MYTNYSLTSSDAMPRTYLVGTASPEMSKKKRQSANCDKPTRRVIHIIDTNEHSEVDLKNELPITCTNEDGEMTSSSWTSQTANDFLKLAYVNAKLDPSLPSQYFKQDIINVLQSLEIPGWSVPGSKESSLNKNLLTLTQIKGALTNVIYKIHYPNLPPLLMRIFGDSIDSVIDREYELKVIARLSFYDLGPKLEGFFENGRFEKYIEGSRTSTQADFIDRDTSIKIAKKLKELHCTVPLTHKEITDQPSCWTTFDQWIKLIDSHKEWVSNNVNISENLRCSSWNFFLKSFKNYKRWLYNDSAFTSKLLREDDKDSMINSGLKMVFCHNDLQHGNLLFKSKGKDDISVGDLTIIDFEYAGPNPVVFDLSNHLNEWMQDYNDVQSFKSHIDKYPKEEDILVFAQSYINHMNENHVKIASQEVRILYNLIIEWRPCTQLFWCLWALLQSGRLPQRPLIEGEKLMSEKAGLGDETHLMEHKNKENGKYDCSEDDSFNYLGFCKEKMSVFWGDLITLGVIDKDCPDIGKTDYLDTKLIF", "length": 534 }, "evidence": [ { "id": "G3MZM9", "url": "https://omabrowser.org/oma/group/G3MZM9/", "database": "OMA" } ], "glygen_name": "Yeast", "common_name": "Baker's yeast" }, { "uniprot_canonical_ac": "Q04902-1", "protein_name": "Probable glutathione-independent glyoxalase SNO4", "gene_name": "SNO4", "tax_id": 559292, "organism": "Saccharomyces cerevisiae S288C", "sequence": { "sequence": "MTPKRALISLTSYHGPFYKDGAKTGVFVVEILRSFDTFEKHGFEVDFVSETGGFGWDEHYLPKSFIGGEDKMNFETKNSAFNKALARIKTANEVNASDYKIFFASAGHGALFDYPKAKNLQDIASKIYANGGVIAAICHGPLLFDGLIDIKTTRPLIEGKAITGFPLEGEIALGVDDILRSRKLTTVERVANKNRAKYLAPIHPWDDYSITDGKLVTGVNANSSYSTTIRAINALYS", "length": 237 }, "evidence": [ { "id": "G3MZM9", "url": "https://omabrowser.org/oma/group/G3MZM9/", "database": "OMA" } ], "glygen_name": "Yeast", "common_name": "Baker's yeast" }, { "uniprot_canonical_ac": "Q0D2J5-1", "protein_name": "Zinc finger protein 763", "gene_name": "ZNF763", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MDPVACEDVAVNFTQEEWALLDISQRKLYREVMLETFRNLTSIGKKWKDQNIEYEYQNPRRNFRSLIEGNVNEIKEDSHCGETFTQVPDDRLNFQEKKASPEAKSCDNFVCGEVGIGNSSFNMNIRGDIGHKAYEYQDYAPKPYKCQQPKKAFRYHPSFRTQERNHTGEKPYACKECGKTFISHSGIRRRMVMHSGDGPYKCKFCGKAVHCLRLYLIHERTHTGEKPYECKQCVKSFSYSATHRIHERTHTGEKPYECQQCGKAFHSSSSFQAHKRTHTGGKPYECKQCGKSFSWCHSFQIHERTHTGEKPCECSKCNKAFRSYRSYLRHKRSHTGEKPYQCKECRKAFTYPSSLRRHERTHSAKKPYECKQCGKALSYKFSNTPKNALWRKTL", "length": 394 }, "evidence": [ { "id": "G3MZM9", "url": "https://omabrowser.org/oma/group/G3MZM9/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "Q0WX57-1", "protein_name": "Ubiquitin carboxyl-terminal hydrolase 17-like protein 24", "gene_name": "USP17L30", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MEDDSLYLRGEWQFNHFSKLTSSRPDAAFAEIQRTSLPEKSPLSCETRVDLCDDLAPVARQLAPREKLPLSSRRPAAVGAGLQNMGNTCYVNASLQCLTYTPPLANYMLSREHSQTCHRHKGCMLCTMQAHITRALHNPGHVIQPSQALAAGFHRGKQEDAHEFLMFTVDAMKKACLPGHKQVDHHSKDTTLIHQIFGGYWRSQIKCLHCHGISDTFDPYLDIALDIQAAQSVQQALEQLVKPEELNGENAYHCGVCLQRAPASKTLTLHTSAKVLILVLKRFSDVTGNKIAKNVQYPECLDMQPYMSQPNTGPLVYVLYAVLVHAGWSCHNGHYFSYVKAQEGQWYKMDDAEVTASSITSVLSQQAYVLFYIQKSEWERHSESVSRGREPRALGAEDTDRRATQGELKRDHPCLQAPELDEHLVERATQESTLDHWKFLQEQNKTKPEFNVRKVEGTLPPDVLVIHQSKYKCGMKNHHPEQQSSLLNLSSSTPTHQESMNTGTLASLRGRARRSKGKNKHSKRALLVCQ", "length": 530 }, "evidence": [ { "id": "G3MZM9", "url": "https://omabrowser.org/oma/group/G3MZM9/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "Q1LYG5-1", "protein_name": "Elongation factor 2a.1", "gene_name": "eef2a.1", "tax_id": 7955, "organism": "Danio rerio", "sequence": { "sequence": "MENFNVDQIRATMDKKSNIRNMSVIGAFDHGKSTLTDWLVSEAGIVSSARAGETRFMDTRRDEQERCITIKSTAISIFYELAEKDLAFIKECKDGSGFLLNLIDSPGHVDFSSEVTAALRITDGALLVVDCVSGVCLQTETVLRQAIGERIKPVLMINKMDRALLELQLVPEELYQIFQRIVEKVNVTISTYAEDEKGPMGNVMIDPVIGNLAFGSGLHGWAFTLKQFAELYVKKFAGKAQLGPEEYIKKVEDMIKRLWGDSYFDSTTGKFSESATSPDGKKLPRTFVHLVLDPIFKVFDAIMNFKKEETVKLIEKMGIKLDVEDKEKEGKILLKAVMRCWLPAGEALLQMITIHLPSPVTAQIYRCELLYEGPGDDEAAMGIKNCDPKAPLMMYISKMIPTSDKGCFYAFGRVFSGCVSTGLNVRIMGPNFTPGKKDDLYLKPIQRTVLMMGRYVEPIEDVPCGNIVGLLGVDQFLVKTGTITTFTKAYNMRVMKFSVSPVVRVSVEVMDPADLPKLVEGLKHLAKSDPMLQCIIEDTGEHIIAGAGELHLEICLKDLEEDHACIPLKKSDPFASYRETVSDGSKQLCLAKTPNKHSRLFMKACPLADGLAEDIDKGRVTASQEMNARAQYLAENYKWEVTEARKIWCFGPEGTGPNILVDLTKRVQYLNEIKDSVIAGFQWATREGVLCAENMRGIRFDIHDATLTSTAIHRGPGQIIVATRRVLYGCQLTAEPRLSEPIYLVEMQCPESVIGNVYGELVRRRGVVFSESQVMGTPVYLLKAYLPVSESFGFTADLCANTSGQAFSQCVFDHWQILPGDPMDPTSKVAHIMADIRKSKGLDEAIPALHCYLD", "length": 854 }, "evidence": [ { "id": "G3MZM9", "url": "https://omabrowser.org/oma/group/G3MZM9/", "database": "OMA" } ], "glygen_name": "Zebrafish", "common_name": "Zebrafish" }, { "uniprot_canonical_ac": "Q1PEY5-1", "protein_name": "Probable 3-hydroxyisobutyryl-CoA hydrolase 2", "gene_name": "", "tax_id": 3702, "organism": "Arabidopsis thaliana", "sequence": { "sequence": "MASHSQVLVEEKSSVRILTFNRPKQLNALSFHMVSRLLQLFLAYEEDPSVKLVVLKGQGRAFSAGGDIPPIVRDILQGKLIRGAHYFKVGYTLNYVLSTYRKPQVSILNGIVMGGGAGLSTNGRFRIATENTVFAMPETALGLFPDVGASYFLSRLPGFFGEYVGLTGARLDGAEMLACGLATHFVPSISLTALEAELYKVGSSNQTFISTILDAYAEYPHLNQHSSYHRLDVIDRCFSKRTVEEIFSALEREVTQKPNDWLLATIQALEKASPSCLKISLRSIREGRLQGVGQCLIREYRMVCHVMKGDISKDFVEGCRAVLIDKDRNPKWQPRRLEDVTDSMVDQYFERVEDEEGWEDLKFPPRNNLPALAIAAKL", "length": 378 }, "evidence": [ { "id": "G3MZM9", "url": "https://omabrowser.org/oma/group/G3MZM9/", "database": "OMA" } ], "glygen_name": "Arabidopsis", "common_name": "Mouse-ear cress" }, { "uniprot_canonical_ac": "Q1ZXA5-1", "protein_name": "ADP-ribosylation factor-like protein DDB_G0292332", "gene_name": "", "tax_id": 44689, "organism": "Dictyostelium discoideum", "sequence": { "sequence": "MDFIISFIKNLFGFLTIKKVMILGVENVGKTTLLYNIYKFYSENITTTTLSSLPIPIPTNGFNVESIVIEQVKFDIWDIGGKETNRICYRHYLTSEIDSIIFVFDSSDINSLEESKKEYQYLKNQISLKNVPFLLVANKQDLKQQTIEIDEILKTYFDKSSINETILMSQNNNDDLIKCINWIFSN", "length": 186 }, "evidence": [ { "id": "G3MZM9", "url": "https://omabrowser.org/oma/group/G3MZM9/", "database": "OMA" } ], "glygen_name": "Cellular slime mold", "common_name": "Social amoeba" }, { "uniprot_canonical_ac": "Q1ZXJ4-1", "protein_name": "Acetyl-coenzyme A transporter 1", "gene_name": "", "tax_id": 44689, "organism": "Dictyostelium discoideum", "sequence": { "sequence": "MLFTLLKRHFGNELNNIVWLVLLYLIQGIPIGLSFGTIPFLLHKHATYTQIGIFTISTYPYSLKLLWSPIVDSYFVQSFGRRKSWIVPIQILAGIVFITISFFIETLLEHAETKIIYITIVFFLLIFLMATQDIAVDAWALTILSKPYLHYASTCQTIGLNTGYFLSYTIFLTLSSPKFANKFLRSVPSEEGIITLPGYLQFWGILFIILSIYLAFFKDEESTTITTTTTRHDNYNNNNNDDKNKQVKSKIENESIESKSMRSSPSSLSPSLLSSPVKKQNKKNKQHISIDKKDITIIKENNENNEIIDNNNSNNNYDNGKKSIVQETYGMDISESDLTPKQVYYLLWKIITLPHIKILSILFIISKIVFQPNESALNLKLLEKGLRKEDIASFSLIQFPSIIIFSIISSKWVKNKPLTIWSNAYLVGVFFILVNMCSVFYFPNLNGGEISWSHFFLLLMISLFSSFSYNLMSVSQGSFFLKISDKSIGGTYVTLLNTIANFAGTYPKLFILMLIDKLTTSECIVNISNDNSSSSSSSSSLISTSSNNLTTTTTIIQEQQQQVIIHDNISKELCAEQNGKYRIERDGYYLVATGAIIYGVFIYFVLKRYLTPIEKLKL", "length": 618 }, "evidence": [ { "id": "G3MZM9", "url": "https://omabrowser.org/oma/group/G3MZM9/", "database": "OMA" } ], "glygen_name": "Cellular slime mold", "common_name": "Social amoeba" }, { "uniprot_canonical_ac": "Q23888-1", "protein_name": "Large ribosomal subunit protein uL2m", "gene_name": "mrpl2", "tax_id": 44689, "organism": "Dictyostelium discoideum", "sequence": { "sequence": "MVLNWRGVKSRLYSGKRRIDGRNKGLIAIRSRGGALKRKYRYIEHYKQKWMDKWLFVMRIEYDPNRSAHIALCSILKEGIYFYVISIAKLEVGSLIITSALKLGTLQVGNTTKIKNIPEGLLINNIELIENSGSKISRAAGTSSLIIKKYNKKYSLVKLSSKECRLISNECYATIGTVSNIERKLKQNKKASYSRKRGIRPIVRGLAMNPVDHPHGGRTKGGVHWKSFSGKLAYNVSSRKKTKMTSRYIIIGHRKQKIMDKQIKNG", "length": 266 }, "evidence": [ { "id": "G3MZM9", "url": "https://omabrowser.org/oma/group/G3MZM9/", "database": "OMA" } ], "glygen_name": "Cellular slime mold", "common_name": "Social amoeba" }, { "uniprot_canonical_ac": "Q24113-1", "protein_name": "Protein no-on-transient A", "gene_name": "nonA-l", "tax_id": 7227, "organism": "Drosophila melanogaster", "sequence": { "sequence": "MEGAVKKNSLNSSPLPQRQQRGNSTNKNLGKPTPPKLNAASDGNPAEKKARLGGNTQNGGGVAGGGGTGGGGGGGGATGGVEFSRNRNRGGNQNENRQGFQVANNSHQKQINESPKPAAGNVPAKNNELSAGGGGQNQPNHSNKGQGNQGDQGEQGNQGPNFRGRGGGPNQPNQNANQEQSNGYPGNQGDNKGGQGQRGAGGGKHQRGNRSRRSGGSGIMNSSMGGGGQRGEDFFIAQRLLDISGPTHELPPIELPTDNKFVGRNRLYVGNLTSDTTDDDLREMFKPYGEIGDIFSNPEKNFTFLRLDYYQNAEKAKRALDGSLRKGRVLRVRFAPNAIVRVTNLNQFVSNELLHQSFEIFGPIERAVICVDDRGKHTGEGIVEFAKKSSASACLRLCNEKCFFLTASLRPCLVEPMEVNNDNDGLPDKTLNKKSLEFRHERSVGPRFACLNSFEHEYGSRWKQLHDLFKSKQDSLKRELKMEEDKLEAQMEYARYEQETELLRQELKKRELDNERMKLEWEMREKQAEEIRKREEEYMHRYQNQLLRHEEDMRARQQENDLLMQAKKLNMILDQQEGFGGSNSGFEHFDSPFEVFGNNSNNSTMAGPGGPDNSDGNQHGHIDSWGHRRF", "length": 630 }, "evidence": [ { "id": "G3MZM9", "url": "https://omabrowser.org/oma/group/G3MZM9/", "database": "OMA" } ], "glygen_name": "Fruit fly", "common_name": "Fruit fly" }, { "uniprot_canonical_ac": "Q2PRK7-1", "protein_name": "Odorant receptor 106-10", "gene_name": "or80a10", "tax_id": 7955, "organism": "Danio rerio", "sequence": { "sequence": "MANETFVKNVDSFIITGFDHLQNQKLLGSLILISYMFILLGNGINLCIISTDRHLHKPMYILICNLAVVDIMYSSTCSTTMISVLLAEIKTVSYYSCISRTYFFNLGDLTECMALTLMAIDRLIAINLPLRYHSFVTNSRILWLIFLTWIFSFAVIGFLTYVADTLPYCQPIIKYVFCSYSSLVRAACVDPEPYFAISTVYSMVTLCGLFPFILCTYAVLAYSVTKLANSSRKQMINTCLSHIIVLFSFYLPKIVYILLTRIGLVLTLTERNAVLIVSCFVSLLVNPTVYCIRTKGIRKRITDIFLYTQKITK", "length": 313 }, "evidence": [ { "id": "G3MZM9", "url": "https://omabrowser.org/oma/group/G3MZM9/", "database": "OMA" } ], "glygen_name": "Zebrafish", "common_name": "Zebrafish" }, { "uniprot_canonical_ac": "Q2YDJ5-1", "protein_name": "Uncharacterized protein CXorf66 homolog", "gene_name": "", "tax_id": 9913, "organism": "Bos taurus", "sequence": { "sequence": "MNLFIYVLLLSIWTSSCLDRNESNGSATAVTTHAEFKQTKLQELRRRLLIIVIGTLITGYMVSCTCLLHYSCDSEEAHTAAKDKKEDITIKASRSSKISFTDSKSPTAGLGDPERQSVVSRIDKSSGPSSPRKVPSSAEKLVRPSSQKKPSKPSAPKKVLGSPPQEKLHRTRSPKKAHRQAHAHKPVSQVSPSYPEKAIKSTWPPSLQCRAKPTKTPLPYPKNQSFPEQSSVDKLTKRQRYLKLKCPASAGRAEILSRPHPVKFCRCYKEKCLVCRAVSEPFITHVSDANKKHVPVPLFSRELKHFYKSYKKKQPKYNTLYGNMSDSDITTYNSDGESDREVIIMCNIKCKEDIYKNSRNN", "length": 361 }, "evidence": [ { "id": "G3MZM9", "url": "https://omabrowser.org/oma/group/G3MZM9/", "database": "OMA" } ], "glygen_name": "Bovine", "common_name": "Bovine" }, { "uniprot_canonical_ac": "Q3L180-1", "protein_name": "Alpha-defensin 26", "gene_name": "Defa26", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MKTLVLLSALFLLAFQVQADPIQNTDEETNTEVQPQEEDQAVSVSFGNPEGSDLQEESLRDLGCYCRKRGCTRRERINGTCRKGHLMYTLCCL", "length": 93 }, "evidence": [ { "id": "G3MZM9", "url": "https://omabrowser.org/oma/group/G3MZM9/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q3TR54-1", "protein_name": "Gasdermin-C4", "gene_name": "Gsdmc4", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MGYSFDRASKDVVKKLQGRDLRPVECLSDATKFRLFHILQETPRSGWETEDIPVGFTLLDLLEPNFPVPEPEVSAPKPFIHVQSTDLEANLNVADIARGGVGYVGYGGYNIEVQSTSIPNPKLEILQNRKLLDKLPTFMKFCRMERKNLYVVTEAYEVSKDTMLTGLSSVNLLVKGFFKQLFKVRGKAGRSEKYSIPIPKGSVLAYKKQQLVIENNTCVILPSATKKKMTFPDRPLKLYDLPVTLRYQEEVIETGSWIDDIDPIGTIEEPANLNFMCLQHEVSEQTQLLAELSKDVQEVVFSSFLHMLSDRDVLYDLMKMLELNQLGHMDGPGGKILDELRKDSSTPHDVLKDLNLYLLQALLVLSDTQLCLLAQSVKMGLLPHQVELVKSILQTNFKYSSNTPFTLQPQLLAPLQGEGLAITYELLEECGLKMELNNPRSTWDLEAKMPLSALYGSLSFLQQLQKANSSSKPSLSPGYI", "length": 480 }, "evidence": [ { "id": "G3MZM9", "url": "https://omabrowser.org/oma/group/G3MZM9/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q3U0I6-1", "protein_name": "Endoregulin", "gene_name": "Erln", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MGQMVPPRSIQNEDFWKNPWDVGGLTVIGLFTSTFLLFVLFAVVFGYVEKAVFEEE", "length": 56 }, "evidence": [ { "id": "G3MZM9", "url": "https://omabrowser.org/oma/group/G3MZM9/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q3URS2-1", "protein_name": "Zinc finger and SCAN domain containing protein 4F", "gene_name": "Zscan4f", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MASQQAPAKDLQTNNLEFTPTDSSGVQWAEDISNSPSAQLNFSPSNNGCWATQELQSLWKMFNSWLQPEKQTKEQMISQLVLEQFLLTGHCKDKYALTEKWKASGSDMRRFMESLTDECLKPPVMVHVSMQGQEALFSENMPLKEVIKLLKQQQSATRPTPDNEQMPVDTTQDRLLATGQENSENECNNSCNATEANVGESCSGNEMDSLLIMQKEQHPEHEEGNVVCQFPHGARRASQGTPSHHVDFPSAPTTADVPMEEQPKDLSRENISEDKNNCYNTSRNAATQVYSGDNIPRNKSDSLFINKRIYHPEPEVGDIPYGVPQDSTRASQGTSTCLQESLGECFSEKDPREVPGLQSRQEQLISDPVLLGKNHEANLPCESHQKRFCRDAKLYKCEECSRMFKHARSLSSHQRTHLNKKSELLCVTCQKMFKRVSDRRTHEIIHMPEKPFKCSTCEKSFSHKTNLKSHEMIHTGEMPYVCSLCSRRFRQSSTYHRHLRNYHRSD", "length": 506 }, "evidence": [ { "id": "G3MZM9", "url": "https://omabrowser.org/oma/group/G3MZM9/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q3ZCQ0-1", "protein_name": "Required for drug-induced death protein 1", "gene_name": "", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MTVGARLRSKASSLVGRGPLGRLRRAGDEETDAIVEHLEGEDEDPESQDCEREEDGRRAGTPSARRVHLAALPERYDSLEEPAPGDKPKKRYRRKLKKYGKNVGKAISKGCRYIVIGLQGFAAAYSAPFGVATSVVSFVR", "length": 140 }, "evidence": [ { "id": "G3MZM9", "url": "https://omabrowser.org/oma/group/G3MZM9/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "Q4JEI3-1", "protein_name": "Defensin alpha 3", "gene_name": "Defa3", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MGTLTLLTTLLLLALHTQAESPQGCTEDQKLLIMEDQDISISFTGDKGTALQDADVKSGVICNCRPRGCSFKERVYGECGYNGHILRLCCQPLNTMNKKSPSVI", "length": 104 }, "evidence": [ { "id": "G3MZM9", "url": "https://omabrowser.org/oma/group/G3MZM9/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "Q4JEI6-1", "protein_name": "Defensin alpha 8", "gene_name": "Defa8", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MKTLVLLSALVLLAFQVQADHIQEAEEETKTEEQPADEDQDMSVSFEGPEASALQNLEIGWPLKQCHCRKFCRPYEKAEGSCRPGLFIKRKICCIQQWTPGRT", "length": 103 }, "evidence": [ { "id": "G3MZM9", "url": "https://omabrowser.org/oma/group/G3MZM9/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "Q4KL71-1", "protein_name": "Small proline-rich protein 2A3", "gene_name": "Sprr2a3", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MSYYQQQCNQPCRPPPVCPPPKCPEPCPPQVWPGPCRPVMCFEPCLPSVWPGPCRPVVCYEQCPPQPWQSTCPPVQFPPCQQK", "length": 83 }, "evidence": [ { "id": "G3MZM9", "url": "https://omabrowser.org/oma/group/G3MZM9/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q504N7-1", "protein_name": "Pyrin and HIN domain-containing protein 1-like", "gene_name": "Ifi214", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MVNEYKRIVLLTGLMGINDHDFRMVKSLLSKELKLNKMQDEYDRVKIADLMEDKFPKDAGVVQLIKLYKQIPGLGDIANKLKNEKAKAKRKGKGKRKTAAKRQRQEEPSTSQPMSTTNEDAEPESGRSTPDTQVAQLSLPTASRRNQAIQISPTIASSSGQTSSRSSETLQSIIQSPETPTRSSSRILDPPVSLGTAYSSAQALGVLLATPAKRQRLKNVPKEPSEENGYQQGSKKVMVLKVTEPFAYDMKGEKMFHATVATETEFFRVKVFDIVLKEKFIPNKVLTISNYVGCNGFINIYSASSVSEVNDGEPMNIPLSLRKSANRTPKINYLCSKRRGIFVNGVFTVCKKEERGYYICYEIGDDTGMMEVEVYGRLTNIACNPGDKLRLML", "length": 393 }, "evidence": [ { "id": "G3MZM9", "url": "https://omabrowser.org/oma/group/G3MZM9/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q54B59-1", "protein_name": "O-methyltransferase 12", "gene_name": "omt12", "tax_id": 44689, "organism": "Dictyostelium discoideum", "sequence": { "sequence": "MSDWDKTMDLLFGFVTGHIHSRMFETILKFSICDLLEDGPKHYSEISKIIGFKNESYCYRLMRYFVPYKLFNESVVQVGLFSKTPSSTQFSKNGTLKNLGRFHCQDHHYRIFESLPKTLEMGKNQGPSSIGLSSFWEHFETDESYKQLFHNAMKDYTSLIIDRLISKISLSPNFKTVVDIGGSHGFLIGKLLESNPNIHGINFDLENIINSSTSKNENFQHPRLKHVSGDFFNSVPEADCYILKYILHDWSDEKCITILNNIHKSLKPNGKLFINDLVLDPSNYTKEAVFKDILMMQYFDAKERSINEWHQLFEKCGFKIDSVDTSISPQLMIVSKINSSNINLNDCTNFNSEIVEEKLKNSLPQFVNC", "length": 369 }, "evidence": [ { "id": "G3MZM9", "url": "https://omabrowser.org/oma/group/G3MZM9/", "database": "OMA" } ], "glygen_name": "Cellular slime mold", "common_name": "Social amoeba" }, { "uniprot_canonical_ac": "Q54B60-1", "protein_name": "Probable inactive O-methyltransferase 11", "gene_name": "omt11", "tax_id": 44689, "organism": "Dictyostelium discoideum", "sequence": { "sequence": "MECSESLELVDKFACGHILSRMFNVVMKHSICDLLEDGPKHYSEISKIIGFKDDSYCYRLMRYFVPRKLFKESVVQVGVFSKTPFSTEFSNNGTLKKLAKFHCNSFHYKLSQVLPETLEIGENQGPSSIGLSDYWEQIEKNEIYKNEFNDGMIGYTTHILKFLKGKIDLSKFETVVDIGGSHGYLIGSLLDRYPNVNGINFDTDMVINSSNEKYQHPRLKHVAGDFFKSVPEADCYLMKLILRCFSDEKCCELLKIISKSMKSNAKIIILDIILDSSKYLNFDTYLDILMMETLDGKQRSLSEWIKLFEMSGFKIDKYESGSPNYLIISKE", "length": 331 }, "evidence": [ { "id": "G3MZM9", "url": "https://omabrowser.org/oma/group/G3MZM9/", "database": "OMA" } ], "glygen_name": "Cellular slime mold", "common_name": "Social amoeba" }, { "uniprot_canonical_ac": "Q54B86-1", "protein_name": "Hly-III related family protein", "gene_name": "", "tax_id": 44689, "organism": "Dictyostelium discoideum", "sequence": { "sequence": "MPRLDHKKNKEEKDNEPLMMVNNYNIGIQTDNNQEDIQNDYHHFNDLSINIKNNKNNNNNNNKCNSLHHKHYHNRFIINGGNNNNDNNNNNNGDDCCANIELFVDLMLSENEYILSGFRLHTKNSYMECTKSIFKLHNDTLNIWSHLLGALFYLVLFFTSIIKIIKLNNNDGGGGGGIGNNFILNSDEIKLLETIDLPSNFNYLFFQLSCFICFLSSTIYHTYRSHSIVVFKTTLMLDVASIALLILSSVCLIIDSELSCWPYFKRIYLFSFLILILISFLSLPKIMREKRYGLRTFLFAILALQGLVGHLFKIYLQGYFDKDPNQFYNLIGAYTLFGLALSIRRFKVPESFKPGHFDVWVNITFNIVYNII", "length": 372 }, "evidence": [ { "id": "G3MZM9", "url": "https://omabrowser.org/oma/group/G3MZM9/", "database": "OMA" } ], "glygen_name": "Cellular slime mold", "common_name": "Social amoeba" }, { "uniprot_canonical_ac": "Q54BG8-1", "protein_name": "Reverse transcriptase domain-containing protein", "gene_name": "", "tax_id": 44689, "organism": "Dictyostelium discoideum", "sequence": { "sequence": "MIKIMTWNCQGCSTIKSMNQTKNTINLIKPDISILTETNLKKDQNLAQIKNHYSTGGKGKEARGKGVMAINHLEQIEIKNLEEKEGRILKFTAILNNMEINIICIYAPASYDRRKGWFSNNISLEDLEQADIVTGDFNINKYAKIKFKDGSSDKRKFTENETIEFLMMEVGLTEILPNSTTKTTFKDKLIDRTFLSTKMHQLNHSYKIIDKINKSDHNIVVMDFKIPNFTKIYKSPLWKMNSIIIKEDKTIKKIEKIIDHYQETKRKNINITEYWIKFKKKIKKQCITTEKKRILERKKTLSNLANEHTKTKNKYEKETISNEITILQEEERIDRMIKSSINYINNKEIASNLLTSILKKRDSSSQIHRIKNPSNGKIETEQKEITDCFRKYYETLFKEKECDQETHTELLSTWNPPIDKKKLTEMEDRIEEYEVKLAIEKIAEGKSPGEDGITSSFYKIHQHKLIPILTELFNFFLNNEIPTEFKNGILTSIYKGKGDVLEISNRRPITLLNVDYKIYSKIINNRILKILPNIISKYQNGFIPGRLLHNNIIALDLAMEKSDRNTIITFYDFEKAFDSISHKALIRTLNHLKFPRKITNTILSMLTNTNIRVMVNGQLSESFRAGRGTKQGDPISPTLFAIVCECLSTSIRKDNTIIGIKLNQNNSMKIGQYADDTVTLASNIDDADKMDMKVIKFCQATAAKINDNKCVCITKNPKIKTKYKTIGAKEEERYLGFFFNRKGVISKVDDTVNKLENLTKCYSSVSSTLKGRITILKSYLLSQLTFQLYINEINDIKKLENVNANMLFKGDRWAISKERSRRDYEIGGLELWNMATRSNAQKAWIYEQYLREKDDQNCPPHMEVWKSEKENSLSRIHIKCWKAWKLLHHPRERITLKLNQVKPKYENKQKLKVIYRNMMDIKYKGWNKHQPTTGQKLIQKNINHPILPFREARSITTIKGRDLAWRYLLKALPKHHGENCHSCKEEESSMHIFFECKSIKQNIDSIYQKVCKDSNNTYHGPWSEKVLGKLLTPFSSNLIGAIMESIWYRRNQIKFNDNTTIITENQIIHKIKKARDAEWDRTRKIVEKQLRQELRCTDNRESINRTASIKRRLEKFSHNWNSKLMTINIPEHFIPYCSYNTNYS", "length": 1144 }, "evidence": [ { "id": "G3MZM9", "url": "https://omabrowser.org/oma/group/G3MZM9/", "database": "OMA" } ], "glygen_name": "Cellular slime mold", "common_name": "Social amoeba" }, { "uniprot_canonical_ac": "Q54C66-1", "protein_name": "RING-type domain-containing protein", "gene_name": "", "tax_id": 44689, "organism": "Dictyostelium discoideum", "sequence": { "sequence": "MYKTKKYKNPFPTNSYKEPENDSDNEYILHNEEDNEDYGSNNNNINNDGFSYEDNIENSDTEDEREDYGYINYNTNNEEDDEPIDLSTPIKKKKANNKSFKPPYKNTTTTTTTTTTTPPTPPPSKSNNNNNNNNNNNNNNNNNKNKENINKESEYELNKFLDLYNDFKSESDNKVKPTATTTTTTTTTTSTSTSKLNKDKKGVIVIESDEEKEDNTIKINKRNGKRKEGEQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQGNEDNLKSENFNKFKKLKSFSNQPTPLPPMLSNPFLNNSGNSHNNNNNRILFNSQFTNASNLNNNINNNINNNINNNINNNINNNINNRNNNTNNYTNNNNNNNNNNNNTNNNNSNNNINNNNYNNNNNNSFSFLPIRSNTLPTIVTRRTGIQSSSSDNGNSNSNHSSSMNKRNTSKSNNKKSTTTTKTVLPPPLSSRTQEEEDYALALSISEGLNGGSGGGSGSGSGSSDNSTKTKRSKSENDLPNEETRHQVEMDRRFAEQLHREQHENINQIQQLQRRLHLNQQRTNNINRNHHGDEDEEDIEMLNLRAYQQIQQQFNQHFNQQLNQLANHPLANLFSHASRGRGRGARRIPHHPHHHHHPHQAQYLTGLSQEQLNLMTRDFSSNDYELLLQLDENINNKGATTSDIENLPVHTLNKPTATTTSTTTTTNSSTSDDNKKNEPTTDVTCCICLCEMEPGDAVRTLPCKHFFHVSCIDQWLKVNKVCPIDKKAIDEK", "length": 766 }, "evidence": [ { "id": "G3MZM9", "url": "https://omabrowser.org/oma/group/G3MZM9/", "database": "OMA" } ], "glygen_name": "Cellular slime mold", "common_name": "Social amoeba" }, { "uniprot_canonical_ac": "Q54CY8-1", "protein_name": "Obg-like ATPase homolog", "gene_name": "", "tax_id": 44689, "organism": "Dictyostelium discoideum", "sequence": { "sequence": "MIKGIKLFNNFTNTKQILFFRSFSTAAKGDRLKASHYVKTRGSCKSISIVGLPNIGKSTFFNALTSSNAAMAANFPFCTIDPNIGKVFVPDERLDYISDLLKTKSKIGVQLEFVDVAGLIKGAADGEGLGNKFLGNIRQTSLICHLVRCFEDKGITHVSDEIDPIRDIETIETELILADLQSLEKMLTEGKKKQSNPELQMKFDLVKRISEYLHKGLPARDVEITDMEWPVFHSLHLLTSKPTIYTCNVAEGDAATGNKYTDLVKEYSKSKGLEIEPVVISAKIESELANMEGNDETKKEFLQLYGLENNGLSKVINGAYKLLGLQSYYTASSNECHAWTFKAGWTAPKAAGVIHSDFEKGFIKCDTISYNDFIECKGDEKIAKEKGKQRSEGKAYIVNDGDILFFKFN", "length": 409 }, "evidence": [ { "id": "G3MZM9", "url": "https://omabrowser.org/oma/group/G3MZM9/", "database": "OMA" } ], "glygen_name": "Cellular slime mold", "common_name": "Social amoeba" }, { "uniprot_canonical_ac": "Q54D44-1", "protein_name": "Probable polyketide synthase 42", "gene_name": "pks42", "tax_id": 44689, "organism": "Dictyostelium discoideum", "sequence": { "sequence": "MIESQREFNCIGGDNQNGVAVIGVGFKIPLDLENCLSSPSELYSALFNEFDSVTKNTSSRWSDNYFKNGDIVSLSAGLLPLREIKSFDPTFFGINPSDADLIDPQQRLLLKCVWNALEDGGIDPISIRSSDTSVYIGCSTIDYFLLNRNPVDPHNHGIQTASYSIPNRISYCFDFRGESLFVDTACSSSLNAVHLGYNSIINLKSKLSIVGGSNLILDPQNSIFFSKQQVNGPSGKCNSFSEEADGFVRSETVGVVVLKNLKDAIKDGDRIYCVIQGSNSNVDGNYEKLNYISPSKLSQAENITKALKSTNGAVNASDIDYFECHGTGTPTGDPIELEGISIALNRTQQSTTLSNPLLIGSIKSNIGHGEASSGIASLIKCCVMFKYRQFLPNINFKTPNPLIKFKEWNLKVVTEPVPFNNNKQTIMAINNFGVSGSNCCIILSEYKSNNNNNNDFKATTHLKSKKFIIPFSSNSSTSLDNYKSLLSNETNNFQDFVIKQINNKSTSLIQRSVIIASNWSEFNESSNEIQSNIKKSIISNITIKKKNAVTVFVFCGQGSQYNKMALSLYENEHIFKSTMDKLDKELSKHYGYSILEKLRSITDEDLVTIHQPILAIPVNVMVQVSLYELYKHWGIKSDIMVGHSFGEIACSYCSGMVDFKTLCYLTYHRSVAQNKTIGSGKMLSINIGAKEYLDSYSTKYPSVEIACYNSETSIVIAGNEELLNEISKDLKSKDIFTAMLPSLSAFHTTHQSVIKDDICSLNFKSTLSKITVFSTVTSNQFGINNNNNNNNNQLNSNYLFQNVIQPVKFSETISNIYKYIESNDMGNEITFIEIAPHPTLQYYLNQMKSQQSEYFNNGEKISIYSACNKKKNDYNEFLKTISTLFVNGYNNINFKSQIINNNNNDNNNNFNLPLYQWDDNEYYKIHPTWKKANKNGPSINHLGNLNDSSIKSFKTYINTRKPQFQWLKGHSLKGKVVFPGMGYISNLLSVYNMNQDITINEIQFKSAFILVDGVNNCLETSIVPLTKNEFNIKFHFKDLKTNKWVLCANANYSLFKHNDNNDKLDIEKLKSNCNYTIISKDELYNNIRAKSGLIYKGLFQGVKEAFIGNRCSLTVLSLNEIENQQEFKHLLENRNFNSLFNTAILDSCLHGSLHSKEQSQIYFDKCEGFKYYSNNINLATSKRNEYKEINVYIETNPVINSTVIVSLKIMLPDGTLLIEIQKVVCKSSIPIIDSTSVIQPSPKDLHTPYYQPKNSLIKPPQSFKHLHCMKEFASIESDNREMVYMSIYHLIFKAINARSPTKINLESLENLTLDQFKELIKDSAANIQRSNQFIYECLKLYHTNHSNYKKNQIKDFIKECEDFNGYNQIIFKTIKIYAKSLFPLPDDDPFTDTIQSLFEDDQLENVYIHLKHLYPVNNLLSEIVFQSIKPIINQTSTFRILEIGAGYGTISQLIFDKLEQLLADNFTSSRIDIEYTFTDISNTFLPRAKERYSKYKRFNIIYKLLDLELPLTEGIQDFRPLYYDIVVMSNVLHVVKDINFSTNEIYKVLKQNGQLIFVEPTYKNLYLDTIFGIFPQWWSFNDDIRTDRCCLEPSKWFEFLETINFKDTIILGQDNKEILKNVENSIILVQTRKPSQLELSINNSPSTNQFKSFENIILYTDDNQQPNDCSEIIDLLKSLELPIKIINNIDQFNQIIKTQYNNNNNNNNNNNNNNNNNNNNTNNNLIIFLKSVNQLNTNNYKDITFEYVQINQILVKLELEENYKLLLITNNSQSSNYLSNSLIGTSRYLFADIVSSKLDIITIDFDTVSIKNHQNVISVINHLLDSKDNSEREYYIINNEINIERYKNESNIKHQLKSKTFQENKDELMVQLDSNLEYRLKSKSKQELKSTHVEIQVKAIGINYKDYATYSGLIDSIIEIDKDKEKDENYDQNYPSIGNDFSGVITRIGSDVRKFKVGDEVCGLAPKTSASHIITEEGYLCKKPSNISHSEAASSVTVYTTSFQSIYSIGDLKKNETILIHSGSGGIGLSALEILKWKNHQGYIFATVGSEDKVKYLTDTYGSFITGIYSSRDKDYQDQIKEKLKSLGCDIDHQGVDLILNTLSVEYMDSNFKCLNQKGRCIDLSITHLTPFDYMDYNKFKFNVSYGNIELVVLPSKIIKDHLKKMLKAFSLGSLRFIPIVEFSNLNIRNAVEYINQRKHIGKIVVKNDVDFINKLFIEQQQQQNSVENNEILMKDKYDISNLELGKNILLTGQTGIILTILKWLYKHSNNSIENIIIISKSKLKWELELFINESTNNRIKIHYKQADVGNNNELNQCFEELRLRHSIEDINSIFHFAFINDIGQFEDVNMNRMDIAHHAKAIGSLNLHNQSIERKWNIKQFVLASSALSVFGGDNQCCYISACSVLDSLSKYRKSIGLPSLSINFGGVTSTGFVSRSGAVEANLESSIINLITPQSLISSLDLFIQNSQTFSNYTHFNFIYDNIESYSLNRMLFKFDYLINQHSSLVSNKRLGGINENNNIGDLLVSKIGELLSIEPSKLNLDFRLVDYGLDSLVIVQLKNFIDKQFQPHLISILQLQNNKISTTIEIIIKGYNNNQNKKIKNEQSNDIPSVVQKETIKDNNENKDDIKIDMDDKKENLKGKKENIDDKKENNN", "length": 2655 }, "evidence": [ { "id": "G3MZM9", "url": "https://omabrowser.org/oma/group/G3MZM9/", "database": "OMA" } ], "glygen_name": "Cellular slime mold", "common_name": "Social amoeba" }, { "uniprot_canonical_ac": "Q54E06-1", "protein_name": "Transmembrane protein", "gene_name": "", "tax_id": 44689, "organism": "Dictyostelium discoideum", "sequence": { "sequence": "MTIINNDNISLATSAKLSQFIVSGDYKGPFTIIGLKTKILSFSLVIEFILLKIELIKERKDGLKINFDDSISGSCNYELNYTKQDTLFQRFQSKFKIEHTINPENGETINTGITLKKLFIISIPMSILFVALNWIWMLAISMTEVSISTALYLKILKTISVIIFMGGIVGIAITTVGTSKGEYPHAIKGEILMIISAAMWGLYEVLTSKFIGDANRTIVHTYMGLIAFVNLILGIPVIVILNVTNFEPFSVPSISVFGMLLLNAFVGFSVNYLINWGLSVTSPLFVRSGELMVIVATLLFDIIIKHMKLPLLALPGYSLIVIGFILSVYIESRDIKQQQEKEKEKQKNNNGETESLLNY", "length": 359 }, "evidence": [ { "id": "G3MZM9", "url": "https://omabrowser.org/oma/group/G3MZM9/", "database": "OMA" } ], "glygen_name": "Cellular slime mold", "common_name": "Social amoeba" }, { "uniprot_canonical_ac": "Q54EC9-1", "protein_name": "DUF781 family protein", "gene_name": "", "tax_id": 44689, "organism": "Dictyostelium discoideum", "sequence": { "sequence": "MLNKIILIFFLINNIFSIVVSSTKLNPWVFEERIKLYDILINSTKVEIFGDDNLNNCFQGFKIQLEWQKTTGRSMIIDNSNISVNSWWGSMNYYESIIPFISAMNLGIIQPPIELVNIGDDRFCTDYSECDKELMEPWDLYFQFLIKIKDEKYSYSIQQQILKYNWDGHMKSLSIGLKLFNDKLNYLSKNEIKFSTGFVHFVDIISLINFNTNYSQILPIFDSLPPRMLTNSDHPPFFKGFTRTQNFYTVSVLSINELHENQILWNYFLNLLKTKTENEKCRDFINQEIINFTKYPESTLVKLLLKLLLNNC", "length": 312 }, "evidence": [ { "id": "G3MZM9", "url": "https://omabrowser.org/oma/group/G3MZM9/", "database": "OMA" } ], "glygen_name": "Cellular slime mold", "common_name": "Social amoeba" }, { "uniprot_canonical_ac": "Q54ED6-1", "protein_name": "Probable polyketide synthase 41", "gene_name": "pks41", "tax_id": 44689, "organism": "Dictyostelium discoideum", "sequence": { "sequence": "MDSKNLVDENCNKVAIIGIGFRFPNLKGDITPNELWSKLLNRYDGIVKNDRWNESFFKSGDISTNYAGFIPFEELKSFDPLFFGINPSEGIHMCPQQRLLLKCTWEALEDSGIDPIEIRGSNTSVFIGCSGADYQNLNKNDNKVQQEIFSSSTHSISNRVSYCFDLHGESMTIDTACSSSSNAIRRGYKSIIDGSSNISVVGGINILLDPNISKSYSRLNILSKDGKCKSFDAGADGYVRSDAAGIAILKNLNDAIKDDNNIYCVIDGSASNVDGNGFSDKSNFYSPSKSSQVECIRLALESTNGQVNENDIVYFEAHGTGTPTGDPIELESVSIALKTSENRSSDNPLLIGSFKPNIGHTESASGISSLIKCCLILKNQCFVPNLNFNKPNPLIKFDQWNLKVVTDPIDFSTLNYINKRVSIAINNFGVTGSNCCLIVSSFKGNQIRNNINNKSKSPKQYLIPFSTNSIKSLDLYKSRIDNNVEFKEFAENQIKSKSKKLIQRSVVIASNWDEFNLKSNTINTSNDKLTSNMLVSSNKKNVTMVFVFCGQGAQYSTMAKNLYDNEPIFKKSMDKIDSKLNEYYGFSILEKLRSFNENDLKGIQYSIIAQPSTCMVQISLFELYCHWGIKPSIIVGHSLGEISSSYCSGMIDLDTFCYLIYHRSMVQSKTNGLGRMLSISIGENEYNSKYSSRYPELEIACYNSPSSIVIAGKELILNEIIKELKKDGVFCAILGSPTSFHTSSQLSVKDEILKISFKSKQPTIPIFSTVTTNLYDEMNPFDTKYVYDNIINPVRFTNTISNIYKHIELNYSVNNNSNEVIFIEIAPHPTLSFYLKQMVPEDKKQSVSIFSPLSKKKSNDLFEIQKLISELYCLGYNGIGFNIQLSDHNNTNNQTRVNLPLYQWEDQEYWKLDNLHQYHLSNGPSINHLGISNSNHTPIKSYQTHINIQKKPFQWLKGHQIKGKYYFPGCGYIDNILKIFGESKTDTNPNKELPDILISFIEFKTPLIFMDGISQCLQTNIHSTGKKEYKALFHFKDEKSSSDWVQTSTANFQLFSRGPNLNEDDEQSLFMYNINDLISNQCNLTKLSKQELYSHIKTKCGLNYSGDFQRVDKCYLGYNCSLSEISIIQGVNENRSTFFDSSIIDCCLHGSIGLIDENCQLVFEKLEELTYYSSKVPKTTSQHSKIYVYSKLKPRIGDSYSASIIVMLENGTVLFEMENASFKSTTKIKDPLAMEYPTNEIYSCNLQSKDSLIPSLSSFDHIFKRKIPNEYVDQINIYESFIPKLLFSNINKRCPEITIDEIQSSEIEQLLLKYYKIKEDNDNKWLSRLFTFAFESIKQWYHNEDYDFENVLSPHNFKIFSKSTKIISKLLFPLENDNDEDSPQSLFEGGLLDKFYSSGFSAQNELVGEIIQESIKPILNEKLVFRILEFGGGVGSLSLLVLEKINSLLIQYPNYQIDIEYTWSDISPSFITEAKAKFEKFNDRFNIIYKALNLEQPLIGEKQGLKPQYFDYIIMFNVLHVIKDVKYGVEQIYQLLVPNGHLLFIEPIYKSIIGDGIFGVFDQWWSFQDTEIRKDRCCMKQKTWYKLLKSVNFNDDIRMTPELTCFVIQAQKPSISNLSFSKSETTNYDSIIVFGNKYASNLSNHFIKSIDNGNLQFISTIEELNKIGKYISNESIIYFIKSIDELSVDNFVNITHEYTQINQKLMELNCKCKHVLITNDSTTTNYLSSSLIGAARYYHECPLELFILNFDTPSIIENQNLFKTIEPLINSSINIQREFIINNHKVYYERIKNETKLKSIFKNSSSFESLEQVDNFMISLTPNLEYKVKVKPTSILKENEVEIKVMSTGLNYKDYLIYAGLVESVEPIFGIEFSGIITRISTGSKEFKVGDHVYGIGKSTTSSHIITDIDVISHKPSNISHSEASSIPVVYLTSYHSLYNIGALKNNETILIHSATGGVGLSTLEILKWKGHSGLIFVTVGSNEKEEYLRENYGDMISGIYSTRNKNFVKQIKSKISKLNPFGKSGVDFILNTLSSSDYMDSNFKCLNMSGRIVDLSITHLNSNEFTDNKKFKYNYGYHNIELQYVDKKIIKSTLSIISNAVSSNDLQLIPITHYSIEKVKESIEFINERVHMGKIIINHENQDSIINELIEKQKSINKFDQSIFKQNYKLEPSLLGRNILLTGQSGIVLEILKWILRNSENNSIGNIIILSKSSIKWEMEYLINKVKLINKLGNFFNNIKFHFKSVDISDSGLIDESINKLLIENPDINNIDSIFHFAYTQATCNSDEVDLHHLTQSHSAKSMGAINLHNQSIKRNWKLKNFIMSSSVSSKTSTANQCGYISSNNVLDALSKYRISIGLPTICTNYGLIESTGFVSRNESVAALLSGEGFIPISANLILGTLDLQLQNQAQSSNLILSNFNFTSLNGLPQKSLISKFDYQININEENEKSKSLLKDDNVELTVDQLITFKISEILSTDILKLNKDIILVDYGIDSLVIIQLKNWVDKEFSIPNELTIQKIQNSTINSFIQLVKNSMDKNKK", "length": 2542 }, "evidence": [ { "id": "G3MZM9", "url": "https://omabrowser.org/oma/group/G3MZM9/", "database": "OMA" } ], "glygen_name": "Cellular slime mold", "common_name": "Social amoeba" }, { "uniprot_canonical_ac": "Q54ED7-1", "protein_name": "Probable polyketide synthase 40", "gene_name": "pks40", "tax_id": 44689, "organism": "Dictyostelium discoideum", "sequence": { "sequence": "MDYKNKYQSNENCNKVAIIGIGFRFPNLKGDLTPNGLWSQLLNKYDGIVKNDRWNESFYKTGDIPTKYAGLIPFEELKSFDPLFFGINPSEVIHMCPQQRILLKCTWEALEDSGIDPIEIRDSNTSVFLGCSNFDYQNLNKNNNKIQQNIFASSSHSVSNRISYCFDLHGESMTIDTACSSSSNAIRRGYKSIIDGSSNISVVGGINILLDPNTSKSYSQLNMLGKDGKCKTFDADADGYVRSESAGIAILKNLNDAIKDGNNIYCVIDGSASNVDGNGFSDKSNFYSPSKSSQVECIRLALESTNGGVNENDIVYFEAHGTGTPTGDPIELESVSIALKTSENRSSNNPLLIGSFKPNIGHSECASGISSLIKCCLILKNQCFVPNINYNKPNPNIKFNQWNLKVVTDPIDFSTLKLSNKPISIAINNFGVTGSNCCLIVSSFKGNQTNNNNNKSKSPKQYLIPFSTNSIKSLDLYKSRIDNNVEFKEFAENQIKSKSKKLIQRSVAIASNWDEFNLKSNTINTSNDKLTSNMLVSSNKKNATMVFVFCGQGAQYSTMAKNLYDNEPIFKKSMDKIDSKLSEYYGFSILEKLRSFNENDLKGIQYSIIAQPSTCMVQISLFELYCHWGIKPSIIVGHSLGEISSSYCSGMIDLDTFCYLIYHRSMVQSKTNGLGRMLSISIGENEYNSKYSSRYPELEIACYNSPSSIVIAGKELILNEIIKELKQDGVFCTILGSPTSFHTSSQIPVKDEILKISFKSKQSTYPIFSTVTTNLYDEMNPFDTKYVYDNIINPVRFTNTISNIYKHIELNYSVNNNSNEIIFIEIAPHPTLSFYLKQMVPEDKKQSVSIFSPLSKKKSNDLFEIQKLISELYCLGYNGIGFNIQLSNLNENDNIQTSLSLPLYQWEEQEYWKLDSLYQHHLSNGPSINHLGISNSNHTPYIKSYQTHIDIQKKPFQWLKGHQIKGKYYFPGCGYIDNILKIFGDNSESTTNPNKELPDILISFIEFKTPLIFMDGVNQCLQTNIHSTGKKEYKALFHFKDEKSSSDWVQTSTANFQLFSRGQGLNEDDEESLFKYNINDLISNQCNLTKLSKQELYSHIKTKCGLNYSGDFQRVEKCYFGNNCSLSELSLSQGVNENRSTFFDSSIIDCCLHGSIGLIDENCQLVFEKLEGLTYYSSKVPTTTSQHSKIYVYSKLKPRIGDSYSASIIVMLENGTVLFEMENASFKSTTKIKDSLAMEYPTNEIYSCYLQSKDSLIPSLSSFDHIFKRKITDEYVDQIKIYESFIPKLLFSNINKRCPEITIAEIQSSEIEQLLLKYYKIKEDNDNKWLSRLFTFAFESIKQWYHNEDYDFENVLSPHNFKIFSKSTKIISKLLFPLENDNDEDSPQSLFEGGLLDKFYSSGFSAQNELVGEIIQESIKPILNEKLVFRILEFGGGVGSLSLLVLEKINSLLIQYPNYQIDIEYTWSDISPSFITEAKAKFEKFNDRVNIIYKALNLEQPLIGEKQGLKPQYFDYIIMFNVLHVIKDVKYGVEQIYQLLVPNGHLLFIEPIYKSIVGDGIFGVFDQWWSFQDTEIRKDRCCMNQQTWYKLLKSVNFNDDIKMTPELTCFVIQAQKPSISNLSFSKSETTNYNNIIVFGNKDDSNLSNNFIKSIDNGNLQFISTIEEFNKMTKYISNESIIYFIKSIDELSVDNFVNITHEYTQINQKLMELNSKCKHVLITNDSTTTNYLSSSLIGAARYYHECPLELFILNFDTPSIIENQNLFKTIEPLINSSINIQREFIINNHKVYYERIKNETKLKSIFKNSSSFESLEQVDNFMISLTPNLEYKVKVKPTSILKENEVEIKVMSTGLNYKDYLIYAGLVESVEPIFGIEFSGIITNIGSGNKEFKVGDSVYGTGKSTTSSHIITDIDVISHKPSNISHSEASSIPVVYLTSYHSLYNIGALKNNETILIHSATGGVGLSTLEILKWKGHSGLIFVTVGSNEKEEYLRENYGDMISGIYSTRNKNFVKQIKSKISKLNPFGKSGVDFILNTLSSSDYMDSNFKCLNMSGRIVDLSITHLNSNEFTDNKKFKYNYGYHNIELQYVDKKIIKSTLSIISNAVSSNDLQLIPITEYSIENVKDSIEFINERVHMGKIVVDHENQDSIINELIEKQKSIDKFDQSIFKQNYKLEPSLLGKNILITGQSGIVLEILKWILRNSENNSIDNIIILSKSSIKWEMELLINKTKLLNSNSINSMGNYLNKIKFHFKSVDISDSGLTDKGIHELLIENPDINNIDSIFHFAYTQATCNSDEVDLHHLTQSHSAKSMGAINLHNQSIKRNWKIINFIMSSSITSKTSSANQCGYISSNNVLDALSKYRISIGLPTICTNYGLIQSTGFVSRNESVAALLSGEGLLPISTNLILGTLDLQLQNQAQSSNLILSNFNFTSLNGLPQKSLISKFDYQININEENEKSKSLLKDDNVELTVDQLITFKISELLSTDILKLNKDIILVDYGVDSLVIIQLKNWVDKEFSIPNALTIQQVQNSTINSFIQLVKNSIDKKNKK", "length": 2552 }, "evidence": [ { "id": "G3MZM9", "url": "https://omabrowser.org/oma/group/G3MZM9/", "database": "OMA" } ], "glygen_name": "Cellular slime mold", "common_name": "Social amoeba" }, { "uniprot_canonical_ac": "Q54EN3-1", "protein_name": "Alkyl transferase", "gene_name": "", "tax_id": 44689, "organism": "Dictyostelium discoideum", "sequence": { "sequence": "MSNCSNNSENCNINDNKKKEENVKNQNSNKNSNNNNNKSNIESIILNKKSKFSSEKELDEKENKDLKDLSNNKPINIDEYEGLPRFENEQNARSKSSLWSKLCDWMYDQNFKIASSTLKNGPIPKHIGVIMDGNRRFAERNHLETKEGHKKGFNTMLDLCQWGLTLGVKIISVYAFSIENFKRSKSEVQDLMELANNKFTEMISKSHKLQQLGVRIRVVGDHSHIPEKTKSILAKAVKSTENNTKALLNICLSYTSHEEILHSMKILSKGVNQEKKIEIEDIDQDLFENCLYIKEDLDILIRTSGEYRLSDFMLWQSCFTNLALVNTLWPDFSFFHFIYIIFLYQFNSKTLKNEIQNQYKFNNNNNNNTDNNNNLKENIKNLKSDQRVKEFINHLKISEEKLFDEFISKYNEEEEEEEEI", "length": 420 }, "evidence": [ { "id": "G3MZM9", "url": "https://omabrowser.org/oma/group/G3MZM9/", "database": "OMA" } ], "glygen_name": "Cellular slime mold", "common_name": "Social amoeba" }, { "uniprot_canonical_ac": "Q54F52-1", "protein_name": "Saposin B domain-containing protein", "gene_name": "", "tax_id": 44689, "organism": "Dictyostelium discoideum", "sequence": { "sequence": "MKLIFIVCLLLIFNYFIGISFGNKQINSNQQQQIINTDKNYNHNKNNKIIVSHNKNNNNNNNYNEIETENLGCTFCKYLTEKVEEYLQANSTEKEIISYLDEECELLNSPNLVLTCQNLVQQYTPIVIELIDNNESPSVICENVNICPTSSSSSSSSSIEEEIIKKLNIDDNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNEEEEVNTCEICNLVSNLIEKYIKINNEVDEIRELIENECELLSNSKVSSCYSLVDQYFEHFYVTIENNYSANEICQLFQFCPIESSSSSSSSDIINNIPLQDSGCTVCTVLANYAYKVQANESIPEIIGSMDEICNKIGAWRDICNSIMRSGGQQLVEDIVNKGEGVYTACSNIGYCQSSSSATGTSGFSSGGSGTSTGGGYSTGDFYYKPLK", "length": 416 }, "evidence": [ { "id": "G3MZM9", "url": "https://omabrowser.org/oma/group/G3MZM9/", "database": "OMA" } ], "glygen_name": "Cellular slime mold", "common_name": "Social amoeba" }, { "uniprot_canonical_ac": "Q54GT5-1", "protein_name": "Endoplasmic reticulum junction formation protein lunapark", "gene_name": "", "tax_id": 44689, "organism": "Dictyostelium discoideum", "sequence": { "sequence": "MGNLFSKKNGFEKQLLDMETKILNLEDKLSNSRIFHQKVLHKIVLYSFAIEFFIILFTYVKSRSLESIPEKLFCCIYLVLFPIFILILTKVYGFVYKYLIKKNEVRLDSLKTGLQKKLDERKRETDYENTQKLLDRYEKNPPSPTNKPLGPPNLNNNNNNNNNNNNNNNNNNNNNNNNTLGNSMRNRNQPFNISSQQNQQQQRMIQPQQLSPQQLQLLQQQQRLSQQIVPSQQQQSQSQPQQQQPILNQPYNINNNNNNNKPPPPIQLPPQQSSQYIGNQQRLPPQQYQNEQKSKWWLDKLVDYLISDGPTHGSPLICSNCHSHNGYVPVEELSNIQFRCRVCKTFNQRDSVNNSTTNDDRNNSQNTGSNQQQSQSLQDQQPSIEEIDKNFSVTEQKNETNNENYSDSEKQLEENNNNNNIDNDSGSSSSQNTPNKKKGKGKGKGTPTKKTN", "length": 452 }, "evidence": [ { "id": "G3MZM9", "url": "https://omabrowser.org/oma/group/G3MZM9/", "database": "OMA" } ], "glygen_name": "Cellular slime mold", "common_name": "Social amoeba" }, { "uniprot_canonical_ac": "Q54H60-1", "protein_name": "Uncharacterized protein", "gene_name": "", "tax_id": 44689, "organism": "Dictyostelium discoideum", "sequence": { "sequence": "MLDFFHLKDVDEFFRLLEKKNLQNLDNQIDGPGNLNWRTTYTEKDFSKVPKFRGIIHIVQIRDLGTKIHRDLLYEIMFEKLLDIARLNNESKLLKNEIQDLKTKLDEYHNNNSTTNTDLIINSFINVIDTTTTTTTTKTTMGATSIDKKQSEGDSIDKSIELDFFKIKSDQSQQSSPSHKLEEKQNQVNNITNEIPQESIKTVKQQTQTETNQQTFSSTSPSHQNEEKQDKQEEVKQEEVKQKEGIQKEDKKEEDKKEEGKQKYGEIFIIEIPQEEEKQKEEGKQQDGENFIIEIPQEEDKQKEDKKEEDKKEDKQEEDKQKEEKLEDKQKNGEEFIIEIPQNETLEIKVDTHPRSSNDDVSTAEMEVEALKTPLFAETTFVTKQQVITNKKLLVYKQSDFFPNMTTLLQSRLKDVTVQEVKDLTKIGLNDNSYSVGDFENVFVLYAVSCMGARTDSERDAFKIKSIRSIIGDKVPIIYGVFMIGKNGPTRIKVEHTQTSISITHSMSDIGRNLQNNENLKQLQSFLQQ", "length": 529 }, "evidence": [ { "id": "G3MZM9", "url": "https://omabrowser.org/oma/group/G3MZM9/", "database": "OMA" } ], "glygen_name": "Cellular slime mold", "common_name": "Social amoeba" }, { "uniprot_canonical_ac": "Q54H72-1", "protein_name": "Tudor domain-containing protein", "gene_name": "", "tax_id": 44689, "organism": "Dictyostelium discoideum", "sequence": { "sequence": "MSNIDFEDYEFYDDSDFEINTVDESVMTYSSVFDFLRFGKIPKFDTQTKMKHFKDNISKYRIESKDILHTNVDSKILRRLSEIPRVEKIFPDPNTLQLEVFKPNHELRNSNGELLSKHRPLQETLKLIEKQYYWECKFIHTSMEVDITKLYSFCDLCSQSSVSRDMDIDSNDEDKILEQMDIVEKSFSNDRNNNNNNDDNNKSIDEKDKMNICGIGIDLEAIKEGKLFEDELAEALGFPEYNSSVDNSFNSSVNNSNLNNSSLNNSLNNSKNNNNNDDDNNNNNNNNNDDNNNNNNNNNNNNNIISNIDNNNNNNNNNNNISNIDNSNNNNNNNNNNNNPVNDDFSFIIPKDYQSKNHLNDNENKDDEKDDDKDDDKDDDKDDKDDDKDDDKDDDKDDSKDNGYIKTNVSLSSSSSSDNERDDGDSHSDKSVDNDENNNNNINNIISDCNNNNNNNNNNNKINGRTFTSRRTRSDSNTSNSSVGSYISNSSKSSANSYDFSSSDQDYKSPNSPTVKKTRGASLVNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNINNSILKPKLKSKRASASTAINSFISQFITPKHPPKSSSRLKRANRSNDSSDSGDSSSNNSSRSSSDSSDNENNNSYYLPIQSRRSTSKQILKDHLKSPTKKPRRIIEEDFYHVEEKKSPTSKISTPISRSASYNFGRSSPGSSPGSSPSLSPYSSPPQSPPHVYNHNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNYNNNNNNNNNIRSILKSPQSPSISPIKTPRRSPQQQQQLQLQLQNYIPMPTKTKTPTKAPYVPNYALAPIEPKPTQKTPVHVFGGNQLSVKKRQTIEDMITEVLKMNVDTAALKLPLPKVGQHVEGKSNMEDYKDAWFKGVVKEVLPNDFFLISYIDGGEEELSYTRLKPNLTSELEPLKLEEIVVGGEYLGSYRNFYYNVYVLEILRHSIRVYFADLEMAKTIKYSQLYLLSSFVKR", "length": 998 }, "evidence": [ { "id": "G3MZM9", "url": "https://omabrowser.org/oma/group/G3MZM9/", "database": "OMA" } ], "glygen_name": "Cellular slime mold", "common_name": "Social amoeba" }, { "uniprot_canonical_ac": "Q54HE0-1", "protein_name": "Conserved oligomeric Golgi complex subunit 5", "gene_name": "cog5", "tax_id": 44689, "organism": "Dictyostelium discoideum", "sequence": { "sequence": "MNNNNNNNEGVSSSSSSSSSPLPNISSPNLISNSNIENDIEIKKKSNNNNNNIFEGDNSHIYNQFLGEDFNVVHYTSNALKVSSISLSLNTLTSCTRELGQELTENITTNYDDLFKLANNIKELDQLTDTLKLGVSNLEESIQRMKNDISEPYNKVKSHIGQLKRVQDSCELLRKLIRYIQLVKKLKNHLQAGSRDLSKSAQCINEINLLKKDSDLTGINIIDSQVVWIKTCSDQIITISSTLLYQGMENQNQTDVANSLQVFHNMTILNEKVYSIVNLTTEKVIKNIKALLNVNKLIADLPKTTITNNINNNNSNNNITTNNNNNNYNNNNNNNNNNNIISTSTDKSIWLKFESLIDTLYSSLIQILHLQRVLLKIKDPLTHKSLMEVLLIKQHQLQQQQQQQQQQQQQQQQQQQQQQQQQQQVGTTSNNTQPILIEMISTLFWKSILKVLENNLLVAAKSSNIIENTFIREYPKVSKFFLDFIKKLQNYIDIHQMDIQQQFMIVLSNINQIIGNNNSNNSNSNSNNSIESSLSTSSSSSSSSSSSSSTTTTATTSLILLSADDYKLSLFKSIGLFEKAYLEYSQSKMSTIVNGLFPQSTWSSRSTLPVIPNGKQLVDLSKTIWSEIEWLVGNNDRQLLGKLMLVVSKVIDLFSSKIESMVQPPGLIVLNSNIGSSSSTGGVNNNSNSNNNNEIITINENSKPTPSQTVNTLLFNVSIQLNSSIQSLLTSQPLERESIIVIEKSLNSLITICTNIITPLMNSFFTHIEQIFSTIHNEDWYNEKTTKMLINKSNQTCSSYMESFKTLVNYFQNQYLMRFTPCQLLNNQIKSMISKIFIVYLKYCSLLKQPFSENGKLKMVNDLTHLEFAVTPLLVSGGIKEIGESYNLIRNYKQSIFN", "length": 898 }, "evidence": [ { "id": "G3MZM9", "url": "https://omabrowser.org/oma/group/G3MZM9/", "database": "OMA" } ], "glygen_name": "Cellular slime mold", "common_name": "Social amoeba" }, { "uniprot_canonical_ac": "Q54IX3-1", "protein_name": "Probable polyketide synthase 26", "gene_name": "pks26", "tax_id": 44689, "organism": "Dictyostelium discoideum", "sequence": { "sequence": "METNNNKNIQEDIAIIGFRIPGCQDNTPSELWNNLMNKFSGVGKTTERWSDNYHLSGDINNGNSGLLPLKEWKKFDPAFFGINPTMVSTIDPQQRILLKCTWEALEDAGIDPIKLRGSNTSIFIGCSTGDYLDMVKSNNEIQTNLFGSVNHSLSNRISYCFDFHGASMTIDSACSSSLNTVLLGCQSINQGKSNLCIAGGVNFILDTTIPTAFSFLNILSKNGKCMTYDEGADGFVRGEGAGLVVLKSLKDAIKDGNNIYCIIKGGNTNVDGNGNADKANFFQPSKQSQSDNIKLALESIKKKSMLDIDIDYVETHGTGTPTGDPIEVEGISKVFKENHSPENPLLIGSLKSNIGHMEAASGVTSLIKCCLMFKNKSFAPNVNFQKINPKIKLDEWNIKVVTEAIPFKKNKITSMVVNSFGVTGSNCCLVLTESINNNNNSNVDKITKNEKEYLIPFSANSNQSLKNYIEEVSKIDESLQFEDFVYKQLSNKSTSLFQRFVVTSKDWKELKYKLSQPLPLKEISSSISVKKPNPITVFVFCGQGSQFNKMGLELYNNDKNFRNYIDRFDKKLLEYYGYSVISKLRSIDDNDLITIHDPIIAQPATAILQISLFELYKHWGINPSFIVGHSLGELPMAFCSGMIDFDTVCYLLYHRSLAQSKTNGCGKMLSCNISSEEFVKNYSPRYPFLEIACYNSPNSIVVAGKESILLELSKEFKNSGIFCAMLGSLSSFHTSSQLEVKDHIYSLKFESKEPVIPTFSTVTTHLFNSNKLYDNDYIFQNIMKPVLFNETISNLYKHVENNQLGSEMIFIELAPHQTLSFYLKQLIPKDSNYFSNSNSITILSPLHKKKNDYLEIQQTISTCYCKGYDVNFKSQILIESKTNISNKSLPLYQWDDKEFWKDLEKQKRILQGPPMDTLGFSNEKSPILKSFETKIDIKKKPFQYLKGHIVKGKIYFPGVGYIENLLKMYPSQDIDIDSMEFEAPLILIEGIVTCLQSNVYKIGKNEFKVQFHFQDQKTKQWIQSSFANYHLSHRDDFDPTTNKLNIQNLISNNCNLTKLSKNQFYNFIKAKAGLSYNGEFQGVEKCYLGDNCSLVEIPFDTSNQDVETNINMIPILDSCLHGVHILYVEQCQMVLEKIEGLKYYSSTLILSKQKEQQKLYVFTRIENKDLINNSISASIIVMISDGTVFFEIESVSLKSLIPLKDPISIENPTDELFSSYLQSIDSLISEPSSYKSIYKRNEFISSGMSDLSRSDYQQFISTLLYTNLIKRNQSIESDLRNQIEFEEIKAKYCKNSKFERLFTFVIETIKQYDGINGNLNSWNEGNIDIYKILIKSTRIISKLLFPLQGEDTTIDTPQSLFENNLLDDFYNINGNTVIQNQLVGEIITQSIKPLINEKMVFRILEFGGGVGSLSIVTLNKINQLLEQHPNFQIDIEYTWTDISPSFIPDAKKLLSNIKGVTIIYRSLDLEESLIEKQLLKPSYYDFVIMSNVLHVIKEIKFGIDEIYKVLSPNGQLLFIETPYRMLICDSIFGVFDQWWGFTDTGIRVDRCCMKQKTWFKLLSESNYQDIIMSDDIKDCCFVIQAKKPSISSLEYKLKIDSQENDKIIVFGENDTFMKYLENKSTKQIIKIKTCQQFSDLITSNSKEINNQSIIYFIKTLNQLLIENFKEITLEYIQINQLLLSSGLSCKHILLLNQSTSENYLGSSISGAARYFDEFPPLKLYSFDFDKYSLNNESINIIDDIIEPIIKSMNNSNIRKELLVRNNKIFFERYKQEKRIKENYKSTSFENDKSLFVHLNANLEYELKSKQVKLKQNEIEVNVKATGINYKDYLVYTAMTPSELINHKGESNPEFGHDFSGIITRIGDDDGDNDNEFKVGDQVYGIWFNTTASHIIVDKEFLCHKPSKLSHTIASSIPVVYITSLYSLYNIGNIQNDESILIHSASGGIGLSALNILKWKNHKSHIFVTVGSKEKEKYIHDTYGDFITGIYSSRNKDYLKLIKRKLTELGSNKKGVDIILNTLSSSEHMVSNFKCLNHRGRIIDLSITHLNHNEYTCNNNFKYNYGYHNVEVLFVKGDIISKLLKNITSAIENGSLSTGIPIIEFNDSDCFNAIEFINKRQHIGKIVVNHNKENLIQELIKKTNLPIIKSNYQINSDHLGKNILVTGQSGIILEILKWIVKYSTNVENIIILSRSSLKWELELLVNKNKNKLNFIYKSVDVGNSLEIEKVIDEILMENPQINNVDSIFHYAFTQISCKEHEIDQVHLNVSHQAKTMGAINLHNQSIKRNWKLINFIMASSAAGLIGSTDQCSYVCSSNVLDTFSKYRKHVLGLPSICINYGLIESTGFVSRNQSVAVMLDGQGIRPMQTNQILGSLDLFIQNPSKSTNIILTSFNFNEFATGNLQQSNVHKFDFQFNCCLSQKSKLMANNQASENPVKDLLINNICELLSIDESKLNIDIRLIDYGSDSLTIVQIKNLIDKNLLIPNLISIQMLQNNSISDNIKILTDSYNKKKQNEQNELKNIKVGSFTKK", "length": 2531 }, "evidence": [ { "id": "G3MZM9", "url": "https://omabrowser.org/oma/group/G3MZM9/", "database": "OMA" } ], "glygen_name": "Cellular slime mold", "common_name": "Social amoeba" }, { "uniprot_canonical_ac": "Q54K45-1", "protein_name": "Uncharacterized protein", "gene_name": "", "tax_id": 44689, "organism": "Dictyostelium discoideum", "sequence": { "sequence": "MTKILYLIIYLTLTIVKGAPLYNCKKLNCSSMNTNCKVFGCSPMFGCFETSKCPQSNVDICHTNHCDENTGSCYQIADTCNDGNNNTIDSCGPYGCVNTPVNPPEPTQSCEQKCNDNNPCTVDFCDFRGDCYHYETRCSDYDACTLDTCGEKGCEYRPMNCDDNNPCTADFCSMLYGCYHEPIECSVKVPCRTDSQCNRNNFCETYSCDLSSNICDYYTRDCGGNPCINNECRTGTITN", "length": 239 }, "evidence": [ { "id": "G3MZM9", "url": "https://omabrowser.org/oma/group/G3MZM9/", "database": "OMA" } ], "glygen_name": "Cellular slime mold", "common_name": "Social amoeba" }, { "uniprot_canonical_ac": "Q54K50-1", "protein_name": "Phospholipase D Y", "gene_name": "pldY", "tax_id": 44689, "organism": "Dictyostelium discoideum", "sequence": { "sequence": "MIINRLFIIIVLFFVNVNSKIISESTLNSCQGGTIQIAESIPLGLDISTNLSTHDAWMDLITNAQESIDLGFFYFTLLGGSDLDPVYGGQLGIDIFNAIVEAHSRGINVRIVQNEPSESFPDTETQTLAKLGIQVRSIDWVSLVGSGVLHTKLIIIDESSAYVGSANADWSSLAQVKELGIVLKNCPTMVADTEIAFQQYWNAADFTSLPINDWGSNYQALFNNTNMASLSLNNNNNNNNKNKNNDNDGSGTNQMYEMFLAVSPPQFQSTYRTGDIDALMDAINNADQSICITVMDYTPTTLYNDPNTYWPLIDNALRAAAFNRNVQVRMLISHWNYTSPIIPQWLHSLNQVDNIQVRWFVVPDFSTNPQIPYTRVNHAKFMVTEKQSYVGTSNWSQDYFTVTGGLSYNVFNNDFTNQLQSIFNRDWNSPYTQPIQNF", "length": 438 }, "evidence": [ { "id": "G3MZM9", "url": "https://omabrowser.org/oma/group/G3MZM9/", "database": "OMA" } ], "glygen_name": "Cellular slime mold", "common_name": "Social amoeba" }, { "uniprot_canonical_ac": "Q54K65-1", "protein_name": "Band 7 domain-containing protein", "gene_name": "", "tax_id": 44689, "organism": "Dictyostelium discoideum", "sequence": { "sequence": "MNSIKKLSTTAIKFTKQTQRFNKRGFFKILNQYERGVVFNFGKFHTVKEAGFHIVIPFIQKCDIVDIRTFTYTLDKQKIISKDNINLTVDALVVFRIHDPKLAVTKANDCILLVNEMAQIKVCEILSHNTLDQVLHNRDKISNQIHDELKEALNKYGVTIEYLKLKDIHFDETIAKAIAKKVEAANLRDIKN", "length": 192 }, "evidence": [ { "id": "G3MZM9", "url": "https://omabrowser.org/oma/group/G3MZM9/", "database": "OMA" } ], "glygen_name": "Cellular slime mold", "common_name": "Social amoeba" }, { "uniprot_canonical_ac": "Q54KF5-1", "protein_name": "Protein LEG1 homolog", "gene_name": "leg1", "tax_id": 44689, "organism": "Dictyostelium discoideum", "sequence": { "sequence": "MKSNKTIFLILLFLINFNSIYSFNFKKEIKISNDKINLPTYNPWIFQDRFNLYSILINSTNIPVFGEDNSNNCLHGLQLQFEWQNRSGRLEINQGHVNTKSWWGDMNYYLSIIPYLSAMKMGLVPVVEIVSINDQRFCSTYEDCDQEVLNNWDNFFQQIINIRNNGSEGDDQQLLKFMWTAHIGSIDKATKLFTDSLLLLPKNELRFGNGWAHFVDVIATVNFNTNYSTVYHLGQQLPPIMLNSNDTHPSSIESFTKEQRNVVLTMYEINDLSSNNLVWNSFMYLLKKMTKNEICRNLINNEINIFLNSPVPTIIEILFDILTNNC", "length": 326 }, "evidence": [ { "id": "G3MZM9", "url": "https://omabrowser.org/oma/group/G3MZM9/", "database": "OMA" } ], "glygen_name": "Cellular slime mold", "common_name": "Social amoeba" }, { "uniprot_canonical_ac": "Q54KK9-1", "protein_name": "Uncharacterized protein", "gene_name": "", "tax_id": 44689, "organism": "Dictyostelium discoideum", "sequence": { "sequence": "MTEVPNQKHNDGGVGVTVGNFVKDNETNVNNNNNINGKGENDNNNNNNNNTIIDEPKLLNNNNNNILVIPLTTNIIDNELNQQKQHTLPLPLPPPPLPTQPQQITPPLPTQTQLPNNMLPSPRPIQQPKIRQQTQQQQAQMQQLQLQIQQEIQLQLQQQQQQQLQLQQKQNESEINGLFSPNFSSSSSSSLSTTPNMHSPLFNNNNNNNTTTTTTTTTTTTNSSTNNTNSSTQTKNASTNKISQDVIGVFDDTDTESEGEEYHSGRSIDFWNKDYKDIAWRCNWIDLQIRDLQYQSMVCDQLYHKVRRSKQKIIPDNKSLSSSIDNNNNNNLKSIPIETIDHSNNAITSSNIPYSNNEEEQQEQQQHPSQSIRTTSVVKLRKPRKLIRRPTVKLSAKQMTTDLEAHPLFTFHKGYFKFENAIKTNIINEMEIKYQEKEKPPKLLTLSEERLKQYINSNEDVDVVNLFATNESKRLSEKRRGRIPSDKKEKVSSHRLKSGDEIDGTSSSTATATTATTTTTTTTTTTTTNKKSRRSRREKKKEKEREKQEKEKHIKTKDEQKDREKKEKAREKELEKERKREKERIKEKERQEKERLKKEKELEKNKKKEKKLLKEKEKEIKEKKVKLKNQENIIEKDLTINNTTTKTTKSKKSSSKVKKSEQEGVKLENVEIEDEEVEEEEEEEEEVEDEEEEEEEEEEEEEEEEEEIEEVEDNEEEKRKEERRRRRRKRRILRRRKKLRRKQRKRQLFLQKQQQQQLLQQQQQQQQQKLLQQLKKRDESNGLSYKEIITPEWRDISSFANNDPSLPSPLLLSNPLLAQDIKNITTTTTTITTSEPISKFSTITEEELLIRQTTNGIDGTPMNGIGEDSESSGSEIELDEDAMKIIHARNEIEEKRRFFNTIKQIQMENPVPSYKRKKESLPVEFVAPTVEELLPSYHFNKKSIKLLGKSWNGDFEYYSSSDEDDYDDSDDYDSDDDNDDEDDDDSDSDDEDESDSDDYDSEYDSDLSDSDDSESESSDNELDGLYSSESEINHNSSGDEDEMDVELNNHHIPSKNSKNSKKQPVNNNVNNSNNLNGSSGGGKINSKPSKQQPRNSKANPPSKQQPTPLKQQPTPLKQQPTPLKQTTTPSKATPSPKQQSQQQQQQQQQQQQQPQQPQQPQQQQQQSPKPTPPLVSTTPPLSSVPLSPPTKTIRSTRGVSSLSNSTSSLPKQTNTPPISILSRKRNQSQSSVTDAPLSPTTTATTTTSPKPTTRRKGKLQETIPVEETKIIEETKPFEETVPIKENSTTTPLKRTRRQTKQQLVNGETTTPLTNGDNHVEKTDSNSTDVKVDPTSWWGDKQYKIQPVMEATVIRFKRVKNDDGDDDDQIQNNQKNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNINNINNTEDLESKIKETKSINIPMEISTNGNDFQMKEKEGE", "length": 1472 }, "evidence": [ { "id": "G3MZM9", "url": "https://omabrowser.org/oma/group/G3MZM9/", "database": "OMA" } ], "glygen_name": "Cellular slime mold", "common_name": "Social amoeba" }, { "uniprot_canonical_ac": "Q54KU3-1", "protein_name": "Probable polyketide synthase 25", "gene_name": "pks25", "tax_id": 44689, "organism": "Dictyostelium discoideum", "sequence": { "sequence": "MDNSYLNNPQFDINNGNKEVTDDDNNKNNQDNLVAIVGVGFRLPSGENERNNTPQALWNNLINGFDGVVKTSERFNDNFFKNHEIANNYSGLLPLDEVKSFDPLFFGITPNEAQTIDPHQRLLLKCTWEALEDSLIDPISIKGTDTSVFIGSSTNDYLTLNRNEVKSNVFGSMAHSIANRVSYCYDLHGNSITLDTACSSSLNAIALGYDSIKNKKSKMSIVGGVNILLDPYPYKAFSILNMLSKSNGRCKSFDASADGFVRGECIGVVILKNLKDAIKDGNRIYCTINGASANVDGIGYSDKSNFYSPSSISQSENLKNAIQSTNGTVKPSDIDYVEAHGTGTPNGDPVETEGISKVFKDTRSTDTPLLIGSFKSNIGHCEAASGIASLIKCCLMYKNKCFAPNIHFKTPNPAIKFKEWNLKVVTEPIPFNENKNTSMIINNFGVTGSNCCLVLSQFNNTNKQKQQMKTKINNYLIPFSANSVESLKKYQSLIINSKENELKYSFEEFVKNQVFIKPTSLYQRSVIVAKDWNDFNNVENQVKYQTSSSTSSNITITNKNNNPITVFVFCGQGSQYNTMALELYKNEKVFRNSMDMLDNKMKNYFGYSILEKLRAIQDSDKRSVHEQTMAQPSTVIIQVSLYELYKHWGIKASFMLGHSLGEVTTAYCSGMIDIDQLCYLIYHRSTLQIRTNGLGKMLSINISSDEYKTNYMSRYPTIEIACYNSPSSIVIAGNEQILNEISKELKEKEIFSAMLGSLSSFHTSSQNIIKDDILNLNIQSSQPVIPTFSTVTSNLFNESTIFDSEYFFDNISKPVSFTQTISNLYKHIEDNQIGSNIVFIEIAPHPTLSFYLKQMIPKQSQYFRNGESISVYSTLHKKKNDVEEFQKSISQLFCDDAYDINFKCQFNNINSNIEAISNFNLPLYQWDDQHYWLNKSIEHKNNLIGPPISILGNSMQDSNPFIKSYQTIIDTGKDAFKYLKGHNVSDKCYFPGAGYIDNLLKLYPNQDLTINSIEFKTPLILSDDNGQFLQTNVYQTGKSDYRAQFHFKDNRTNVWVQTCTANFQLYNNGKVDKLNLEEIKSTKCNLSSIPWDKFYPHIKNRTGLNYKDKFQNTIECYLGDNCSLTEISLELPENFHDQESFFNTPILDICFHGSIVLIKDNCKLVLDKIDGFKLYTSNIPKNRFDHLSIFVYTTMKSTKSNSYNSTYTVMLEDGTVILEVENLICTSLTPVKDPLLIEIPTDMYYTPYLQSKDSQIQSPLEFKSIYQNNQDNDSLLIPNVVLETIKPLINEQMEFRILEFGGNNLSNSTLLLNSINSLLEENPHYEIDIEYTWSDNNSSILKDAKLELSKVDKGYLSILYRSLGLDVDNSLLEKQKLNPSYYDLIIVSNISNLTKDIKYSLNQIYQILTPNGNLIINEQQPNNENNENNEDSLKNLLVNCNFNSDIMMKSSSVSDSDIKSIIIQAQKPSLKLQPKTINTFDQVILYCNQDEQFQQQQQLINKFESHYNNNCKIIKVSTIEEFYKLSTTITNNSIIYFIKSIEQLTLENFKSITFEYVQINQKLYEFKSKCTHVLITYDSQSSNYLSSSILGAARYFDEIPTLQLFTFDFDKDSLINLDISVIDHLIDPKQNTLIEFFIKKNGKVYFERFKKGLKKNSFKSESYHQITNEQEILISKLDENLDYQLKSKDSILKPYDIEVEIKATGLNYKDYLVYSGLIKLKGDSVDFGLDFSGRVSRVGIKSSKEFKVGDEVYGIGQSTSSSHIIIDSMHACHKPSKITHVQAASIPAVYATSIHSLYNIGNLREGESILIHSGSGGVGLSALEILKSNNHSSPIFVTVGSEEKKQYLINTYGNLITGIYSTRDTNYQKQIKNKLIELGYETHGVDLIINTLSSEFMDSNFKCLNPEGRIVDLTITHLNPNEFIDNNKFKYNFGYHNIELYYCEKPTIKKLLQSISKSIENNTLNYLIPITEFSNSNIKKAIEYINERKHVGKIVISHDTDITNKLIENQPKIDYSLLKSNYKIKNLGKNVLVTGQTGLILDIINWIMKYNSTVENIIILSKSSMKWEMEFLINNNKTKIKFYYKRCDIGGDSDSINKTFDKLFTENPTITNIDSIFHFAVVQITRKVKDIDMKSLNISHDAKTIGAINLHNQSIKRDWKLSNFILASSILSKVGSLDQCGYVSACCVLDSFSKYRLSIGLPALSINIGAMGGSGMVARSELVETVLNGQGYNLTSTNQLLGTIDLLIQNPGQESNNLMVGNFNFPVFNNFKQKIHQKFDFIFNALDSNSENGDGSNIKNSTNIKDKFLNKVSEFLSIDSSKINNDIKLMNYGADSLITVQLKNWVDKEWSPNLITIHQIQSNSIGMVCQIINDNFEKKK", "length": 2380 }, "evidence": [ { "id": "G3MZM9", "url": "https://omabrowser.org/oma/group/G3MZM9/", "database": "OMA" } ], "glygen_name": "Cellular slime mold", "common_name": "Social amoeba" }, { "uniprot_canonical_ac": "Q54KU5-1", "protein_name": "Probable polyketide synthase 24", "gene_name": "pks24", "tax_id": 44689, "organism": "Dictyostelium discoideum", "sequence": { "sequence": "MKQNKINKAEILQVDDKHVEENLVAIVGVGFRLPSGSIENERNNTPQTLWNNLINGFDGVVKTSERFNDNFFKNHEIANNYSGLLPLDEVKSFDPLFFGINPNEAPTIDPIQRLLLKCTWEALEDSLIDPISIKGTDTSVFIGCTESDYHNINKNEVKSNVFSSLNHAISNRISYCYDLHGNSITLDTACSSSLNAIALGYDSIKNKKSKMSIVGGVNILLDSYFFKAYSSLNILSKSNGRCKSFDASADGYVRSECIGVVVLKNLKDAIKDGNRIYCTINGASANVDGIGYSDKSNFYSPSSISQSENLKNAIQSTNGTVKPSDIDYVEAHGTGTPTGDPIEVEGISKVFKDTRSTDTPLLIGSFKSNIGHCEAASGIASLIKCCLMYKNKCFAPNIHFKTPNPAIKFKEWNLKVVTEPIPFNKFKNTSMVVNNFGATGSNCCLVLSQFNYNTINNNINNHNNNHNHNHNHNNIKINNYLIPFSANSVESLKKYQSLIIENKEYESQYSFEEFVKNQIYNKSTSLYQRSVIVAKDWNDFNNVENQVKYQTSSSTSSNITITNKNNNPITVFVFCGQGSQYNTMALELYKNEKVFRNSMDMLDNKMKNYFGYSILEKLRAIQDSDKCSVHEQTMAQPSTVIIQVSLYELYKHWGIKASFMLGHSLGEVTTAYCSGMIDIDQLCYLIYHRSTLQIRTNGSGKMLSINISSDEYKTNYMSRYPTIEIACYNSPSSIVIAGNEQILNEISKELKEKEIFSAMLGSLSSFHTSSQNIIKDDILNLNIQSSQPVIPTFSTVTSNLFNESTIFDSEYFFDNISKPVSFTQTISNLYKHIEDNQIGSNIVFIEIAPHPTLSFYLKQMIPKQSQYFRNGESISVYSTLHKKKNDVEEFQKSISQLFCDDAYDINFKCQFNNINSNIEAISNFNLPLYQWDDQHYWLNKSIEHKNNLIGPPISILGNSMQDSNPFIKSYQTIIDTGKDAFKYLKGHNVSDKCYFPGTGYIDNIFKLYPNQDLTINSIEFKVPFVLTDGIGQCLQTNVYQTGKSEYRAQFHLKDEMNNQWINTSNSNFHLNSNDNYHEEKQKLDIQDIKQTKCNLSSIPWDEFYSLMKTQLGANFYGIFSKVVECYIGDNCSLTEISLELPENFHDEQSFFNCPLIDACFHGTVILYIQKNCKIVTDKVEGLRYYASNIPKNRDEHSSIFIYSTLKSSPSDDLLSSSIVVMLEDGTVIIEVDNLVVKSLTPVKDPLLIETPSDFIYTPYLQSKDSQIQSPLEFKSIYQNNQVDDGLLIPNVVIETIKPLINRKMEFRILEFGGNNLSKSTLLLNEINSLLEENPHYEIDIEYTWSDNNSSILKDAKLELSKVDKGYLSILYRSLGLDVDNSLLEKQKLNPSYYDLIIVSNISNLTKDIEYSLNQIYQILTPNGYLIINEQQQQQQQQQQQQQQQQQQQQQLLNNENNKESLKNLLVNCNFNSDIMIKSSSISDSDIKSIIIQAQKPSLKLQPKTINTFDQVILYCYQDEQLQQQQLINKFENHYNNCKIIKVSTIEEFYKLSTTITNNSIIYFIKSIEQLTLENFKSVTFEYVQINQKLYELKSKCTHVLITCDSQSSNYLSSSVLGAARYFDEIPTLQLFTLDFDKDSLTNDLDLFKTIDYLINPKNNIQREFYIKNSGTVYFEMYKKELKNLKNSYKSESYHDLSKQQDQLVSKLDEHFEYQLNSKQIDLEPYEIEVKVKATGINYKDYLKYNEMIKVNEAGIGFDFSGVVSRVGIKSSKEFKVGDQVYGIAYETSSSHIIIDSLLACHKPSKITHVQAASIPAVYSTSLYCLYDVGNLRDEESVLIHSGSGGVGLSGLEILKSNNHSSPIFVTVGSEEKKQYLINTYGDLITGIYSTRDTNYQKQIKNKLIELGYETHGVDLIINTLSSEFMDTNFKCLNPKGRIVDLTTTHLNPNEFIDNSRYRYNIGYNSIEILKVGKSTIKKLLQSISKSIENETLNALIPITEFSNSNIKKSIESIKERKHVGKIVISHDTDIIDKLIEKESMIDYSILKSDYKIKNLGKNVLVTGQTGLILEVLKWITKYNSTVENIIILSKSSLKWELEFLMNYNNNNNNNNNNNKIKYHFKKCDISNWNLINKTIDQVLKDNPTITNIDSIFHFAALQINKKLKDIDMNSLNVSHSAKTFGAVNLHNLSIKRDWKIINFILASSVVSVLGSFDQCSYVSACCVVDSLSQYRKSIGLPSFTINIGGVSDRGYLSRHKLVEAVLGGQGVELISPNQLLGTLDLQIQNPNMPTNAFVNNFNWPLFKSFKQKLHQKFDFILNPINVDNSISMENDTNQSSSSTNVKNKFLNKVSELLSIDPSKINTNIKMINYGADSLITVQLKNWVDKEWSPHLITIQQIQSNSIGMVYQIINDSLDKKKKEMDEKLLPITAKTTTTTKNDPNDKTEYKYIAGGDCCREFSIKFHYSSVVNFII", "length": 2471 }, "evidence": [ { "id": "G3MZM9", "url": "https://omabrowser.org/oma/group/G3MZM9/", "database": "OMA" } ], "glygen_name": "Cellular slime mold", "common_name": "Social amoeba" }, { "uniprot_canonical_ac": "Q54LI2-1", "protein_name": "DNA replication licensing factor MCM2", "gene_name": "mcm2", "tax_id": 44689, "organism": "Dictyostelium discoideum", "sequence": { "sequence": "MSQNNNNNNNNNNNNNNNNNNKRKTKTPSSVNHNNTKINEDKDLYNFIDKIRDKTDKSHLEDEYDEDDNTKDGKFNKVEDEIKNDIDSEEDDDDIIEDNEHLYDGDEDSENLSSEGEGDDLLDEDLQDQDEEEVLGDEDNHYEMEGLDNETYEDIDKDKKTEVDSILTKRDREEQKTRQATNRHQYRISSFLLDENDENMVDEDTENNKLLEKRKANLIKKRRETIRQQNDNIKKDYDGSVPSFKDGFVNSERYFEDGDGDDDDDDDDFDIGDNGQVVNLEEPDKDKCLREYVCMSGPRNEISKQFAKFLLEFKEKDGFNPIYQESIQKMCAANKESLMINFTHLCASTVFGVWVAEIPTEMIEIFDEVALKVVLRIYPNYRNIVKSIHVRITHLPICESLRDIRQSNLNKLTKVGGVITRRSNVYPQLKHVKYDCVKCKTTLGPFSLDGTFNDSKPPIGLCPQCQSKGPFVMNSEQTVYRDFQKVTLQESPGTVPPGRLPRTKDIILMDDLIDTVRPGEEVEITGIYKHNFDLKLNYSQGFPVFSTIIEANHINKKEDLLSSFILTDEDEREIRKLSKDSNIAQKIIQSIAPSIYGHEDIKTGLALALFGGTPKDVNNKHRIRGDINVLLIGDPGVAKSQFLKYVEKTAHRAVYTTGQGASAVGLTAAVRMDPLTREWTLEGGALVLADRGVCMIDEFDKMNDQDRTSIHEAMEQQSISISKAGIVTTLTARCSVIAAANPKRGKYDSGLNLLQNVELTEPILSRFDIICVVKDTIDSFKDRELARFVVASHINSHPDNQNNPENDYLNRATKQSPISQELLRKYIIYAKRIKPRITDIDKNKISQLYTDLRRESRAGGFAMTVRHVESIVRMAEAHAKMHLRDYVTDFDVNTSIRVMLDSFINAQKNSMYKNLRTKFAPYVIFQKDINQLLTQLLQTLARDFSNYHFARSGDIPDQINIPYDDFDTKARELGISDITSFFRSNEFTSNNQFTLKKDKSTIIYYRNK", "length": 1008 }, "evidence": [ { "id": "G3MZM9", "url": "https://omabrowser.org/oma/group/G3MZM9/", "database": "OMA" } ], "glygen_name": "Cellular slime mold", "common_name": "Social amoeba" }, { "uniprot_canonical_ac": "Q54LX5-1", "protein_name": "U1-type domain-containing protein", "gene_name": "", "tax_id": 44689, "organism": "Dictyostelium discoideum", "sequence": { "sequence": "MKITESNNNNNNNKKDNNKHWCKYCKIFIQDNISVKNHEEGWRHKNNVTRFVSTQNRDKKYQERDQKEAEREINRIKNTGARSFREKDLSRVLDEKKHQQQPQQQPQQPQQQQRIFNNNSNNNNNNNNNNNNNNNNNNNNNNNSNNNNNYHQPQYPTTTTTTTTTNTTASNKNCDNADSKFKEIQEQQRQLLSNNDYYNYYQDRQQLIYDYYQNEGNQPIPEPPLNTSLYGYTESPLLKSRLDSSTDTLSSSSSSTIISPSHQKKRKQDDTNSPIPAKISKDECVNNENKDKSNEKENELNNNNNNNKSGEGEEGEESDDNDDDEEESGSGSESESESSEVDQSESIIGQWQTVDPIESAFGSTRKDSDDEKDKKDKKNKKDNDENKRDEKDYSDVSDADSEEESVNITKRAMANHKKPITLTNVISPTIPSTSKNFESVLSFNKSGVFSLNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNEPPQPTPQITLKFNKPLKQRNTRKTNIEDKQS", "length": 514 }, "evidence": [ { "id": "G3MZM9", "url": "https://omabrowser.org/oma/group/G3MZM9/", "database": "OMA" } ], "glygen_name": "Cellular slime mold", "common_name": "Social amoeba" }, { "uniprot_canonical_ac": "Q54M95-1", "protein_name": "Uncharacterized protein", "gene_name": "", "tax_id": 44689, "organism": "Dictyostelium discoideum", "sequence": { "sequence": "MKLISILFFLFGILFFLKNVESASDVVCSFGYQACGNNCYSPSSGQKCYPGGVVCSFGYEACGNNCYSPSSGQKCNPGGVICSFGYQACGNSCYSPSSGQKCYPGGIICSFGYEACGRSCYSPSSGQKCYPGGVICSFGYQACGNTCYNPSAGQRCFN", "length": 158 }, "evidence": [ { "id": "G3MZM9", "url": "https://omabrowser.org/oma/group/G3MZM9/", "database": "OMA" } ], "glygen_name": "Cellular slime mold", "common_name": "Social amoeba" }, { "uniprot_canonical_ac": "Q54N59-1", "protein_name": "G domain-containing protein", "gene_name": "", "tax_id": 44689, "organism": "Dictyostelium discoideum", "sequence": { "sequence": "MDLDYAIIVLRHHLESNGRFFEISKDDVKNRVTIKNKLTQEERYIDFGEIQNFIQYDEFEYNLLANGFQENLSILKNSILPLTKAPDSCSSNRGKTIGNSSLLINKVNGLIDDDKDTIYLLLIGITGVGKSTFVNMVVNYIEYSNLKDALENATLEQIYTIASKIEIQDENKTHKFSLGDVEDYKIGSSVTQYSRQYRIKLPDGKTLCLIDAPGVGDPQGTLQDNKHFENILHEISSLKKLNAICILMRPDETRATVLFKYCLNQLLLHLHSSAKDNIFFCFTHTRGTMYKPGPTRAILEDHLKKMKDQSDIEINANEKTFCFDNESFNYLAVKKYNATAGIETNFSEDDEFDFGRSWDRSSKEFKRLLEEISKVQPHDVANTICINNARTMISNLAQPMSTCISNINTNIKLMEQQSEKLRNNSIGDESLLYIPVSVVIAEKLENSLLVCTKNGCSSNTDNPCNIDVVSPKWYSSLYWCDNINKMGTCKKCSNTGVLPCLWFDHQVVTIKETPQLNQLPGTDKKTIGQRTKSEIFNERELLVTKMGERKIQFQEEYDTIKTAIVDFSVFLWHHSLIKFNRYYEDYINMQIKQLENSENSQELIQKLNEHLSEYKASVEEIKHNVQNNKASVKTQKEIFATFDKLLTLPNVGYIIQNQIKLKQSSHYKSEAVEIDLFSKMKNKTKQIIK", "length": 689 }, "evidence": [ { "id": "G3MZM9", "url": "https://omabrowser.org/oma/group/G3MZM9/", "database": "OMA" } ], "glygen_name": "Cellular slime mold", "common_name": "Social amoeba" }, { "uniprot_canonical_ac": "Q54ND5-1", "protein_name": "Multiple inositol polyphosphate phosphatase 1", "gene_name": "mipp1", "tax_id": 44689, "organism": "Dictyostelium discoideum", "sequence": { "sequence": "MMVKIKNIIILFCIFGLLSNVSSLSSSSSSSQSSDNNGNLSPIQDYDLEFLSKHLTTKTPYWILTKNGDSNSQGDGSSGNSNSNSNSNSNSNSNSDSSNEPPEQCKLISIDFIARHGSRMPVLNSIEKLKEMTTSILEYKEQVNQGFNWIFNYSVPYPSDIAGNLILQGQYEHYNISKRLLKKYPLFFEPMKYKPQSYSITSTAISRTGISASAFSYGLLQGTGSLGVDGFQPVFIETASLDQDILLRFFATCNQYVDQLKNGTLINKDEQTKWNQMVFPNISNEISERLGLSDIWLPTSNVISDIFEACAYEISINNISDHWCSLLSKQNILDWEYSQDLSNYWLKSYGHEINYQIATPLLNDILSGFDIYINNNNNGSSSSSSSSSSNNGDNSGSNGSSGSGSSTSTSSNDNGSTNNNDNKVEPTSILRFGHAETIIPFISLLGLYKDEQKLFANSSTEQIENRKFRTSVVSPYASNIAMFLFDCGSAADGFKILVQHNELPVLVPGCDEIYCDYQQFKSIFKQGIDNFKWNSYCNINDDDSGSSGGDSGNGNGNDSHSKKSSYFLAIFIPITFLVGGTIGGIFTYFSYEKIMQVKNRKKLTQYGNDEFISSPKSKSFSFKPTKFDSRSPLIQ", "length": 635 }, "evidence": [ { "id": "G3MZM9", "url": "https://omabrowser.org/oma/group/G3MZM9/", "database": "OMA" } ], "glygen_name": "Cellular slime mold", "common_name": "Social amoeba" }, { "uniprot_canonical_ac": "Q54NT2-1", "protein_name": "SH3 domain-containing protein", "gene_name": "", "tax_id": 44689, "organism": "Dictyostelium discoideum", "sequence": { "sequence": "MSNKITTQFARTRQMLFTKTGHSEETIDVQYHYEKERTFSTEERLVKIQKNSKKLIELYKDLNKITTDIAQDACDLYDTQDPMWTPGSKLRDVATNNDKHLLDYTEQMAEPYTKPLSDYISQYKEARKRTEELTTRKVDMDRYKNEVGKLREKGAGSSSKAKLAPTEEKLRICKEGYDSLHEELLNDLPRLNEDKLIFIDYLVASLIKYQSEFHKKVSYEWSPLPSLTKHVDEYSGRDHQPVITSVERSAASINLRSDPVFKSNASIKMKPGAQDQQQYSTVDKDIHQSPNPSNLNLQKSTPNPYGGASAPPPLYGGGGSSTATALYDFTGVDSSELSFRAGDIITIHKSEGEWWEGELNGIYGFAPGSYLRMN", "length": 374 }, "evidence": [ { "id": "G3MZM9", "url": "https://omabrowser.org/oma/group/G3MZM9/", "database": "OMA" } ], "glygen_name": "Cellular slime mold", "common_name": "Social amoeba" }, { "uniprot_canonical_ac": "Q54PW0-1", "protein_name": "Annexin I", "gene_name": "nxnB", "tax_id": 44689, "organism": "Dictyostelium discoideum", "sequence": { "sequence": "MEYKEKEINTSSPSSPSKTQISNIENDSISEKAQEPISEKVQDPISEKAQESISEKEHIESNNVSEIIDLIKSGDQHLNNNNNNNNNNNNNNNNNNNEEENQEINYNDNQLSNEEIVEDVKNSNINNNNTIEKGNSSQNNNKNNNNNYHTEKCDYCLICKCYDYGEITHNIVEDSEILKQSIRYSYVDDTSINSILAHRNYAEKEAIMKKFNDKYNKSLETELASHTHQKYRRTLISILTEPSIYDTLNIENSIKTKNSNTLLEILLTRTNEQKELIKRIYLVKYGKNIEHDIIAKFSNGANVNGNMMKQLLISMLNNDRDSNSNQSLDMNLINTDSNRLYQAGEHKKGTDHEVFIEILSKRSFSHLSELDRVYENSNPKGHSLRKAIELEFGVSKSIKQVKISLLDILLFSKEPSKYWAEQFNRALTSGSWGINEIDLTRLTITQQHQASKIKQAYISHYDNSLINEVSSKTSFRYKKIILSMLTV", "length": 487 }, "evidence": [ { "id": "G3MZM9", "url": "https://omabrowser.org/oma/group/G3MZM9/", "database": "OMA" } ], "glygen_name": "Cellular slime mold", "common_name": "Social amoeba" }, { "uniprot_canonical_ac": "Q54QB4-1", "protein_name": "Kinetochore protein Ndc80", "gene_name": "ndc80", "tax_id": 44689, "organism": "Dictyostelium discoideum", "sequence": { "sequence": "MHNNNLTYQQYQQQQLLIQQQQQQLLYQQQLLQQQQQQQQQQQQQKQYSHGRPSTLGLPSRKPPPMQPQPQPQIQAPIQLTFQQQQQLLQQQQYQFNNNLNTINNNNNNNITNRHSMVTPSTNLGGRSSLGPPSAMLTNNNNNNSNIRNTTFISNSGGNNNNNNNNNNNNNNNNNNNNNNNNNNNNIINNNNNNNIHTQVQPKKSIAPSKSNTISSNTTTTTTAASSSSSSNPSITLRQETRPVNDSKFQSQCLLRLQQFLSQSEKGYPRAITKDNLMSEINGLMKFLCLHIDPHFKLPTEKPEEEIISFFKMMGYRSAGFTKRVFSQVGNAHTRGHLLGAIIWMVELIEYDQIIRQMDSHIEREILNGNTIDENGNLTTTTSATNTNEDGNFNLTTQIFSKHVFKSYEAFLKGDDGNHVDQFLEEKFNEVNELIVKECEESMERQKKIKQEIVNLTQYITNDDIDQLNFKLEQTNQEIIATHDLINDNELEDQKLDQEIDQNQTHFQELEIQQKEHQKKKQEFESRIQIQQSNSVDAKRINQETFELKEELDKVQREQSRHDQLKQEKSKEIKQSINEIEKLIQSYKEICCKASLVTNDNLIIEKYRIIFTHTLNNNNNNNNTNNSSILNISNNIINNNNNNNNNNNNNYEEGIISISDLKLVIKNLQELNLEISQNISKIKQDLLKTSNLNDIQKESISDKELELARIKQKHDKQKNILKQEKQDQTFDITQREENIEQLKSSNKKLIDDGVRELEKTIQLLESQREEHSRLKIDLKQSSEQMKLQYLKRIERFISHRQLIGSQIFDTLRQMEELSLTQKILFPPPPPPPQLSQQHQQLMQQQHQNNTIDIDE", "length": 855 }, "evidence": [ { "id": "G3MZM9", "url": "https://omabrowser.org/oma/group/G3MZM9/", "database": "OMA" } ], "glygen_name": "Cellular slime mold", "common_name": "Social amoeba" }, { "uniprot_canonical_ac": "Q54QD2-1", "protein_name": "Probable cytochrome P450 517A1", "gene_name": "cyp517A1", "tax_id": 44689, "organism": "Dictyostelium discoideum", "sequence": { "sequence": "MEIINVFLFLIILFLVKDFVKKNKKIHTKSPSGPIAFPILGNVVQIRFWELFKIQEHELFGGYSKKYNGVVRAWFGERLFFFVSNYDVVKYFQKDENFHNRPSVLVPGWRYASSNGLGVMSSSDDKWKRAKSSVSQSLRVRTTKKLMEEKAIEFIDSLEKISNNNEIFYPKGHIQGYACSMLFKYMFNQDLSVESGMSRTIGNAVEHVFGNLSKLTAFDCFEIFSPLYDWFFTRRLKGCDIVRQIISSQNENHLKSIDPSKPRDLMDDLLIEYGLNEITKEDTMQINQICFDIFGPAVGTVTITMNWVILQLCNRPELQEIAYQEIKKAVKDDEYVNLNHKQNAPYIVAFIKETMRLCSNGFGLPRTAKNDQICGDFFIPKDAIIFINYLEISQNEEIFKNAKEFNPTRYLDESLPVPNIHFGVGQRACPGRFVAIDKMFLGISNLLLKYKLKTQNGEKIDDSIQFSVSLKAKDYGIKLEKRI", "length": 483 }, "evidence": [ { "id": "G3MZM9", "url": "https://omabrowser.org/oma/group/G3MZM9/", "database": "OMA" } ], "glygen_name": "Cellular slime mold", "common_name": "Social amoeba" }, { "uniprot_canonical_ac": "Q54RM4-1", "protein_name": "Peptidase S8 and S53 domain-containing protein", "gene_name": "", "tax_id": 44689, "organism": "Dictyostelium discoideum", "sequence": { "sequence": "MKVILIYFIVIYLINISFSLKPYQQQQQLHNFNIIENNNNNNRNEKVIIAHPKIPPYWLIENEISNPNDLISFKILLKQNNLNKLNYLFEEISDPKSKIYGEFLSINEINELVKSSESDFNVVLEYLKSFNIGNIENGSEIKVFSDYILVETTIEKVSSMFNSKFSNYKNKNNGNTRNRLNGPAYLPKQLLNSIDFVTGLSEFFENNFKIENYLNNNNKNNGDSDSDSGSGSGSGSSNSYNGGLDDILITPKVLKSYYNVPNELIGKFENNSIGVIAFNDYFSMGALELFDEKFNITTTKDNLKIIGNDCLGKGCDQYESDLDIQYIRSMGENISTDFISFNDAQWILDYLHSVLLMEKPPLVQSISYGWAELLQCDVSNGCSTFGYDSKQYVDRTNSEFQKLALLGISVLVSSGDDGAPSMGGSSGNCPIDGTVYCPTGGCNHTKTMCPEFTIYNLNGGSDSGGSSDSYCFFPMGIASSGCTNILGDPSVLDSGMKIFSEKNKQCNLAIEYDRTNLPHVYSECECKDLVNVTFRNYHFTQYQFNENNGALFVAEYPSSSPFVTSVGATQFLSRDEKITTEVGCTILQGAKITTGGGFSSFQSQPKYQQYAISQFFNTSFNSLPPSFSYCPTNRGVPDISMVGHNYKIYSSDGNNKDFNQCPCKSLPVDGTSCSSPTLAGLIGLINDQLLLNGKTQLGFLNPLLYQMAIDEPRIFNDITGDSSNRCSRSYCCLYGWSTSSNTWDPVTGLGSIDFNLFLSYVLKLKGI", "length": 767 }, "evidence": [ { "id": "G3MZM9", "url": "https://omabrowser.org/oma/group/G3MZM9/", "database": "OMA" } ], "glygen_name": "Cellular slime mold", "common_name": "Social amoeba" }, { "uniprot_canonical_ac": "Q54RX1-1", "protein_name": "Translationally-controlled tumor protein homolog 2", "gene_name": "", "tax_id": 44689, "organism": "Dictyostelium discoideum", "sequence": { "sequence": "MKLYKDLIGNSHDDLLTDRYEIKVGDVTFEVKTKMITKDLNVVVNNNSLGGSISTTVDNNNSITLSTNLEDEFENVEAAGTFQINNLVEQLRLVETSFDKKSYLAYMKLYIKDLINHIKQQPSNSDNEKIEHIQKGIQSFVKTMMDGENFKKYSFFTGSSMDANGLVALMYYKDDDPTTPTFVFIKYGLLQVDV", "length": 194 }, "evidence": [ { "id": "G3MZM9", "url": "https://omabrowser.org/oma/group/G3MZM9/", "database": "OMA" } ], "glygen_name": "Cellular slime mold", "common_name": "Social amoeba" }, { "uniprot_canonical_ac": "Q54S19-1", "protein_name": "PHD zinc finger-containing protein", "gene_name": "", "tax_id": 44689, "organism": "Dictyostelium discoideum", "sequence": { "sequence": "MKNCIVCSKVGQYPLNLVKCYECKSYYHKFCLQSTKIPRGEWYCSSCEIERKNKKNKKRKLDGAGKKNKKNNKDDDDDNDDDDDEGENDEDDEDHQDEDSGEEEDEEEDEEEEDDDDEEEEEGNEKNKIKKRKRIPINQSPSIKKRTKDIDSEEEEEEEEEEEENDSEEERRIQKRKNKIKQQQQLKMKEKKQREKLRKRRRRTRSSRKDDNDQDDDDDDDDNNSNNSDDNDQDENKNKQKRKRRKDKKKDDDDDDDQEEEEEEEEEIVTGKRKRRSLNKVQPNQHLNNENEEDNEEEEEEEEEEEEEEETDSSEEFLENLVCSSCNTGKDEDKILLCDTDNCSRGYHMYCLRYPITSVPKGDWICDFCRFGDISADLHSADDDEDGAINSQKEIEKQKQKQKEKEKEREREREREKEKEKERERERERREKEKKDALRSSFSNIPIPKINNINGSNGSNSNNNNNSNNNGSGVNRQSPPKVISKKSPQQSPKPLKSPTSSSSSTTSSPPPLHQQSKVTSKISPNSQQSIPTINSNINKSPPSQSKNSPPLKPLTPDLKKQIPITNITTSSTTTTATTTTTTTTTANTSNVATTTTLLKPSSQKKPTILSDKKQLNTSGTNLPMNGKKKEDLESSASHSILDMIPPNNKLFNNSIQSAPISWDLSGSQHKLSTSSSSLPNSNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNIKLQQQLQQQQQQLHQQLQQQQLQQQQQQLHQQLQQQKLKQKQIEEEQEKEREQKRLENEQKLLLQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQEFIDQKELEDKLLSQFDNQNLKSPLSLTSTTSSTLSHLPQSTFESSTILSNKTIKQKWKSRILFETDQICQCEIIQIYGMDFKVNPFQNNITSKTLELSFNQVSFDNLPKPIRDEFITKSSTPSTCLDIGAIDLPNSALLIFLPEIPNQSSLYHLIIHFIENRVAGFIDLSNDLSLYIYPYQTSIISLDLIGILIDKKSLSPPSLILNQQQKQQKQQQQEQEQQNQSFDIKNICYIGINHISMNKILTSQGKNYFSFSNFNELTLSSDIKNFDLVVVDNKMVNNQTINKEINNLMQLQPTTNNNNNNNDINNNHDTLLLVIKDVEFSKWLVSQKKFPNSLEIQKIFQQQILFKQSRCIFLLDNSIIIENESSYFVEFISSFGKFKNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNSSNDWTIKISSTIFDELLPFGHQSNVKKKIDEIKRGINQQLIVSYDFSPMVPKQSSDFLLLALRIAHSKKYKQVFLITSNKIIQNQSKRYSNLNLNCLSLEGGIDYIKNINNKFSLKI", "length": 1361 }, "evidence": [ { "id": "G3MZM9", "url": "https://omabrowser.org/oma/group/G3MZM9/", "database": "OMA" } ], "glygen_name": "Cellular slime mold", "common_name": "Social amoeba" }, { "uniprot_canonical_ac": "Q54S56-1", "protein_name": "Reverse transcriptase domain-containing protein", "gene_name": "", "tax_id": 44689, "organism": "Dictyostelium discoideum", "sequence": { "sequence": "MIAKTQIKCTTIYAPAKSNERHEWYKENLTEEILHSDIITGDFNVDCSVDNNLNKYIKTIFDEFEFTEIKNGITFPRNKSTIDRVFVSKKILHLNPIVTTKEIKLKSDHNMVIIELKIPEYEQQKKGERLWRQNLETLKMNSTSLKINKTIKYYNKKFEENTSKWYKLNICEQWLKLKDEIKKLSINIEIRESNKTKNKLKELAEKLETAKDSRAIFLKEEINNILKEQVRIKQANQTNTHINNKETPSKYLTRRLKVQRKTNEIPQILDPSNNCLVTKHEDILEVARRYYENLYQKRECNEDTHHELLKTFNKRIDQKILDEINQPIEGYEIRLGIEKIQEGKAPGKDGLLPTFYKNHINEILPIISKLYNHFWNTTIPKDFKQGILITIYKNKGDPNNLDNYRPITLLNVDYKIYSKIINNRILKFLNKIISPFQTGFVPRRLLHDNIITLNSTIEIIKREINTKEDMEPIITFYDFEKAFDLFSHNAILRTLAHLKLPLKMVLTIMNLLNESETSVYINNSLSKSFTSKRGTKQGDPISPTIFALVGECMATTIINDRCINGVTKETIKILQFADDTATIAYNFMDHFLMNEWIKKFCQATSAKINQTKCSCITFKWNTRTLYTVIKSNERYLGFDFNNKGIKSKINTISDNIRAKLVTWNSTSSTYMGRLIMAKTYALSQLTFHTYINTTPQHNSIENNIVKFVFNTKSKNSLSLQRRQNNYINGGLNLWNLKTRELAQKAWLFERYLHQRVSNTPSSYIKLWEEELKNNNNNKTTTKQNQLQLHWQCKQAWTQLKTPQNKQTHYEHLPKLKKIYEDMMTTQSPEHNKFIPTPGQKEIMTKINSKHLPFKEIKKIINMKGRDLLWRYTLKALPKIYNMPCQQCGEDETSEHIFFNCKAHIKNTQEIFNYTLTKCGHTTHTWNVKILNHLQIALVANLIAIIFDKIWHKRNKLIHDEKEIIIHRQQVIRELIKTQRAAWDRTQAVINKTLRIKSKQRPEEQNKLDSLISLKLLQFSRQWNSPLHAIELPKHLKKYNNSLSTFYK", "length": 1047 }, "evidence": [ { "id": "G3MZM9", "url": "https://omabrowser.org/oma/group/G3MZM9/", "database": "OMA" } ], "glygen_name": "Cellular slime mold", "common_name": "Social amoeba" }, { "uniprot_canonical_ac": "Q54SW0-1", "protein_name": "Uncharacterized protein", "gene_name": "", "tax_id": 44689, "organism": "Dictyostelium discoideum", "sequence": { "sequence": "NQAKSSTIQQPTQTQQSNINNNTAKPRAAPPLKLVITNSNPSLKQKPQSQQTIPQQSVPQQSIPQQTIQQSVPQQQPNQSQQVNVNRTINPQQQQQQQQQQQQQQQQQNINRTAPLPQQSNYKPQPGVIYQQQQQTQYRVGTPLTINRSPMVGMVSKQPMSSSQQQSQSQQNIQRVPCQGKCCAGLAVKPLVPINSITAKPPPYSTMGPRGPISGGFVRTSPTGAIIGPSPQQQTMSRAMVNSMPIQPQIQIKPKPSPLNNGGIPITTTTTTTTNPLNKSSPSTLTQSSNTLASSNNNITTSNSLSSSTSSLPTTSTTPTTKPKSKPRSKSNSNSQTSSSTTSSSSTPSTPTTNSTKNKENTTPNKGDDSGTDNEKSSLSNSSKLLPTAYTMDQVLPFNPNQMFLGPEDKYIKSATRTYHKIPTNPSVMSNNRGAEIPSSLEYILDIPIIHDEPSSKNNPTWGRLILDALRRLVANKKTTRITERLKLDNMYKDMDSRSNQDKLDWKNGLVNEAQLNYLLSFLSNTIPFPDTPEKNKNKYLSSSDSQIINSNDQSNSLNSNNSSNNSTTNNNNSSTTTNSTNNIINNNNNNNTSSVPNSTNNSNNSSPEQQDVIDMELKLEPDNSMNFPIEINMDSLGSYIDDSFTFDNSSYDDTATISSDDKNLPITTVMPPTTSTTSTPQTITNTIPTTTPTIISPPTITTTTTTTKTTSPPTITTTTSPPTITTTTSPPTITTTTTTINSITPTTSTSSTINSNTTPMLDIVIDPVISLELLDENHQQQQNKEVKEENVHSKQQPPQQQQQQQQQQQQQQQQQQQQQQQQQQQQEDFMIQVQTSDLETQTQIQQDKEEIQVKPIVDSKKSGNSPTQIQQQQQHQQQQHHHQHNTLTQGFEFGMMMDIMNSPSSTSSMKRKRDDVDQPINQINNSSMVVQQNNDFFSDFNTIEAPFSSSHHSSQLSFQTPFSPDIVIDSDFQNKKRIVS", "length": 981 }, "evidence": [ { "id": "G3MZM9", "url": "https://omabrowser.org/oma/group/G3MZM9/", "database": "OMA" } ], "glygen_name": "Cellular slime mold", "common_name": "Social amoeba" }, { "uniprot_canonical_ac": "Q54T36-1", "protein_name": "Probable polyketide synthase 19", "gene_name": "pks19", "tax_id": 44689, "organism": "Dictyostelium discoideum", "sequence": { "sequence": "MEFGNKEIAIVGIGFRIPQGKESINNGSVSHLWNNLKNGFSGIVETSERWSDNINLLGEVNNKFGGLLPLKEWSDFDPVHFAINPSEVPLMDPQTRLLLKCTWEALEDAFIDPIDIRGSNTSCFIGCSTLDYSTTNRDFNETSENYFASNVLHTISNRLSFSYDIRGPSMTIDTACSSSLNSITMGFQSIQNGTSNLSIVGGASLLLDPYVSKSFSFLNMLSKKGKCKPFDSEADGYIRAESCGIVILKPLSDAIRDGNNIYCVINSFSSNVDGGGLNDKSNFYSPSKQSQSDNIKLALKSANMKASDISFVECHGTGTPTGDPIEVEGVSMALNSSTTSTPSKPLLIGSLKSNIGHCEAASGVASLIKCCLMFKNKHYAPNVNFDQPNPKINFKDWNIKVVTEAIPFTNINEKPVSMVINNFGVTGSNCCLILSQFIEHSISLNGNNPSYPIESQQQIFLIPFSANSVKSLKNYEDLIINDNNLSTNSFKEFVKNQIYSKSKKLYQRSVLISSNWDQLKTKNKYFKTSNDKSSNITIKRNQPLIVIVFGGQGSQWNKMAQQLYECEPIFRSSMDKFNKELSKYYGYSVLDKLRSIKDDDIISIHQPIIAQPSILMLQISLFELYKHWGINVSFIVGHSLGEIATSYCSGMVDFQTVCKLIYHRSISQNNTNGCGKMLSVNISHSEFIELYSNKYPTIEVACYNSPTSIVIAGNENILKEISLDLKENNIFCAFLGSLSSFHTSSQNSTKNEILPLEIPSRQSTIPTFSTVTTNLFNHETTPFNSSYVYENIIQPVRFSQTISNLYQHIENNKLGNELIFIEVSPHPSLSFYLKQMIPKSSSYFNSVSVLTSTNKKNSNDLDEIHSTISQIYCLGYDINFKCQFNHNDDDVNSIRNNSTIILPNYQFDEQYYWKVDINFEQYRLNGPNVFNNLGKSMINYSSNNKSYESIIDINRNPFKYLKDHIVKGKYYFPGIGYADNIMKLYPNKDIVINNLEFLAPFVLKENVKHILQTNVYQLGNTDYRVTFNIKDNKANQWVQTCTGNFQLISLKDNNNNNNNNHSSKYNINQLLSECNFTTLSKQEVYKYSKLRSGITHLGTFQGIEEFHFGNDLTIARIQINYENFDINGKPVYQTFDKSFFNIALLDNCIQAITGFITNSSQFVFERLEGLKVYSENIPTDKLKYKNIYCQAKFISLEADSYKSSVLVLLEDGTKLLEIEHISFRSTLPLIDELLLNNPTNELFTNNLQCKDSLVNILSIDNNETSSSSGSSNTVTEIIKQTIKPIINEKIVFRILQSFSDSELSKQIIEALNQIFDNSLQEIDIEFTIIDNSNDKLPTLHDSSLIFKNDITQLKPSYYDIIINNNNDETIIKPIFNILSSNGLLLLIIEDDIGIRFNINNLIGVGFNENKIQKSNKVIQSQKSTILSNELTVVPNNKNDNIIIYCEKHSKYTNEFKKLISNNHTNRKQTTISNINEFNQLLPSITNDSIIYFIKSMEQLEMNNFKQITMEYIEINQQLLKHSLTCKHVLITIDSQIKNYLSSSIIGASRYFNEFPSLNLYSIDFDNQLSISSLLNKIINQLIENSNNHIQREYIIRNNSIYYEILKNEKNIKSNFNSNSFEDNDFMTLLDSTNLEYKLASKPKKLKKNEIEVKVLATGINYKDYLIYRGLVVIDENVSISKNPLGLEFSGIITRISDENKNCEFKVGDNVFGVSHDATASHVITDVLYVSHKPNNISHIEAASLPIIFSTCLHGMFNIGNFNIDDDEVILIHSATGGIGLATLEILKWKGHKSPIFVTVGSKDKEQYLIDNYGSFITGIYSSRNKNYVNEIKSKLNQLYGTTGKFNGVDLIINTLPNEFTHSNFLCLKERGKIIDLSITHLNNNEFLNFNNFKFNKSYHNIEFMHINKRVVSRLLKSISNALNENKVKLIPITTFQIENVKEAIEYINQRKHIGKIVLDHSCSNGSIGSDGLLNQLIESDNNEKNHTILKYDFKIDTKNIIGKNIIITGQSGIILEILKWLIKYSPPTESFENIIILSKSSLKWELELLINKTISRKDNNTKFHFKIVDVGDSIEMRKSINQILLENPNIDNIDSIFHYAFTQVTKEVEEIDIESLDISHNAKTMGAINLHEISIEKSWKLKQFVMASSIASLFGSFNQCTYVSANLVLDSLSRYRKSIGLPSTCTNWGTIKSSGFVSRNDSVSKMLDDQGFIPIPTNIILGSLDLQLQNSNKYSNLIVSKFNYDSIKKFASETSTFQRLDFILNSIKEKDNDNNGGENISISESIQMKFLNKISELLSIEQSKINTDIRLGEYGADSLTSVQLKNFIDKENKSNVITLQQLQNNTIGVNIQIILEQIKKLDSNETKGKSKKIIKKDSAPSLEYWRNEMKLDESIQAIKMNPIDFRNDSKVFLTGATGFLGVHLLSNLIKSPNCSVVYCLIRNKKSEPNPINAIINNLKHHKLYHFHNEFELSKVKVIVGNLASPLLGLSKLDFGFVSNQINLIINSGADINLASNYEESKVVNIGGLIELIKLSTTGDYQKPIVGFSSISVFFESPNCKEFDEETVIPTIENINNLPGGYMKSKVVVENLFREAAKRGIPSMLIRLPIIFSHEETGIGHDSDFFQLIIQSCYAVKKYPNIDKNILTSPIGWIGLNTIKMIGNEKCWNKSSSNQLNIYSLNSEVSSIKSSFSFLEKQYGCEMVEYEQWKNIINQSKILSCIKFKTFHSLDRLNGVYNLGHGFGVSKKTKELLQSMNSYEGGMVNEKIIQNHINYIFKN", "length": 2778 }, "evidence": [ { "id": "G3MZM9", "url": "https://omabrowser.org/oma/group/G3MZM9/", "database": "OMA" } ], "glygen_name": "Cellular slime mold", "common_name": "Social amoeba" }, { "uniprot_canonical_ac": "Q54TD0-1", "protein_name": "Peptidase S8 and S53 domain-containing protein", "gene_name": "V4-7", "tax_id": 44689, "organism": "Dictyostelium discoideum", "sequence": { "sequence": "MISKTSLLLLLLSIVALASAISVQRVPIADVTSAPAHFVQNKLAKSYELVQFKILLKQRNLDILEEKFWDVSSPKSENYGKFLSKEEIDSIVAPSPKDVKVVVNWLIDNGLSKNEMIVHSDFIQVRTNVGKASTLFETSFAHYSSSRTALKRIRVVGQASMPMHVLAKVDLVLGLSDFIEDNKMSESMRATKKQVQGSTVSITPAVIKQYYGIPTGQIGVESENFQSIAAFSDFYSSGALQFFDQKFGIDSSTVRVKNVGQNCIAQNCDQMESDLDVQYMTAIGNNITTLFLSSGNGEWIIDWATAIQQYNPIPKIASISYGWAEVEQCEITNSCSTLGIDSVVYVARSNVELQKVGLRGVSVFVSSGDDGAPSFGAASGNCPIDGTKQYCPLGGCNHKSSQCPMITIMESNGTQCFFPMGSESNTCQSMLQNQNIVNGINEFVSSNSKCQVALEQDTQQNYHIYSSCTCDKLKPYSDSDAGFKIVGYSYDQDAGTLFQPDYPASSPFITSVGATQITDVTKPEIVCSVATGAIITGGGGVAITQAQPSYQADAVATYIKSGTLPPSYSYNATNRFYPDLTLVGHAYEIAVPNTLTSNTCPCALESVDGTSCSSPTLAGMISLINDKLIGAGKPTLGFLNPLLYQAAKEQPNVFNDITTGANNCNRAYCCQYGYTATTGYDAASGLGSINFKNFEQYVLSLN", "length": 702 }, "evidence": [ { "id": "G3MZM9", "url": "https://omabrowser.org/oma/group/G3MZM9/", "database": "OMA" } ], "glygen_name": "Cellular slime mold", "common_name": "Social amoeba" }, { "uniprot_canonical_ac": "Q54TX3-1", "protein_name": "Reverse transcriptase domain-containing protein", "gene_name": "", "tax_id": 44689, "organism": "Dictyostelium discoideum", "sequence": { "sequence": "MFNFERIDHGSGKGTGIAIENRDTRKGHISINFKDDDGRILSIKYNSFNSINILLIYAPATISERNTFIINSKSLFKKYNSINHQIIAGDFNNNHDCNSFFGTELRKIIDQDMLLDTGIEENTPTFPRSMKRLDRIYCHPTLLNQNSKLVVHNTVFNKSDHFPITITIQTNRETTTTTTTKLERLPWTLCKEILNNKHIHDGLSELISKNKDKIKSVEEWTKFKNNVIRDYFKKEQNKIKKEKNKRKYVIHKLLGNSDIIPKMRKELNEEISRILEEERKVKAWDIKLKLHLHQETPSKYLTSILKSRAKDKSIFQIKDKDNKTISDKENIAKRFVEFYQDQYEEKEDNEETHKKLLEKWEVDVDLIKKLEIDRPIRIHEVTKAIKTSSIHKSPGLDGINALFYKYHINSIARILTIAFNDLLTNKKEIPTKFKEGVITTIFKKGDELNISNRRPITLLNTDYKILSKILNSRLLDITSKIINKFQNGFVPNRFIQDNIQIMKEVIEISNKRKNNTLITFYDFNKAFDSISHKSITRTLEHIGIPPKFTAILLNLLKDTKNKIKINDFLVNGITIRTGTKQGDPISPTIFALVLEPLLIDIINDNTIKGFTLPNSKSLKLTAFADDIATFTNSTEELMKINTKIQKYCSATSSSLNKEKTVMIAIGDKPHDLPFQESTVPERYLGLNFTKTGLNSKYNTLIQEMKNNLIKWKSQAITMKAKMTILKTYVLSKLTYHQYMDNLNEEQIEEINNMTRWFLFSSVKNTYTEERKYKTMMKIDRAYADWKEGGIKLWDIELRHIAFKIWYMNRLLHNNYNNNNNTLQEWYMEQLSRKKAHTSTLNDMCRHWGVFRVKFYQNHPKINELPDCIRNDNDEPLKLKEIYELMIKDRHPTPRRTEWQKLWAVRYNTAIPKVFININSISHQKGRNTLFRFFSRSLPGINHERDTRCKICGHLFRDPYSHLFTLCQDILDIEKTIISTVNKLSFIKIHRWSMDTLDISKYNRTERIFPNLIGIIAHQLWKIICHKLFNTDESKPEPKFEQKVIETELLNLIETEKFITLKKIKHDEAILKNTNQDLHKYKFNKAWQTPAAPNPLPI", "length": 1097 }, "evidence": [ { "id": "G3MZM9", "url": "https://omabrowser.org/oma/group/G3MZM9/", "database": "OMA" } ], "glygen_name": "Cellular slime mold", "common_name": "Social amoeba" }, { "uniprot_canonical_ac": "Q54U20-1", "protein_name": "Peptidase S54 rhomboid domain-containing protein", "gene_name": "", "tax_id": 44689, "organism": "Dictyostelium discoideum", "sequence": { "sequence": "MIYGDTREFRNIHFHLNNIRIVGAIFGQDGFIHKKIPLATKVISIICSILFALSLVAPSMFGSYKTCLSIESLTNSFLDNLYRIILSNFAHLSIYHIVYNMITFLDLAKLERLTFGTLKYFYLLFLFGIITNLICLFIYFIGRNNVCHLGFSGVLFALIYIESNSSGRDVFLFNAVKIPSKLYPWAMLILAHVFVPRSSFIGHFSGIVVGILFIKGYLDIFILSNQKLSEIESSQLMNIFTTKNSYFPIIKFGGSRRSYNTDRKSLDGLFFELKNLFNPQQQQQRQQQRQQQQPQSPQPQQPQQPQQQPQQQPQQQPQQHQRDNFRNDNNDNSNNYDEYDFSK", "length": 343 }, "evidence": [ { "id": "G3MZM9", "url": "https://omabrowser.org/oma/group/G3MZM9/", "database": "OMA" } ], "glygen_name": "Cellular slime mold", "common_name": "Social amoeba" }, { "uniprot_canonical_ac": "Q54VC1-1", "protein_name": "ABC transporter C family member 15", "gene_name": "abcC15", "tax_id": 44689, "organism": "Dictyostelium discoideum", "sequence": { "sequence": "MIKKIKNIINKIINFFSTIYILCKIYLYYNIKNRYEAYNILSVYGDDDFFNKPCPEDSSNWKDKLTFKWVERIIFVGFFRAPLNLNDISDLPSSLKVENTAPLLKDIIFNDSTIPLIKHIYSKFLPRNYIATGLFVFVSVFSFITPLILKNFLSYVEKIDEQKHIYIGIIQCFLLFLSSFINMASQQYSYWFGFKTSLEVKGALETIIFEKMTKLSNLSKKNYNIGSMLNLMSVDTDFFQYFFCHYYIEIFLFPIQILSLLGFLIYVIGIAGFVGFLVMLITIPLSSFLGTQISKNLSTSMGYADTRISLTGELINGIKFLKQYAWEKMFCERIEEQRKLQLKYLYIRIIYWVLVQIVTQASSGLVLVSTFTTYTLLGYEVSLEIAFTSITILQNLRRPIESLPDCLHKFISLIASAKRIETFLQSSELQNQPFIHNQSGLNDILIRNINFNWNEHNLKLKNNKNNQNNNQNKRSIILSSGEQFEITNDFTFDGIDIQDDNYDYEKEYKINYNNNEEEENFMTDCLLKIKPLIKDRRLQQQQADYQDLLSINLPPPPSENVDFKAPKGLLTIISGGVRSGKTSLASGLLGEICKAVDKSSPDSVNSILSTIQQPFLQSTSFRENILFGKPMNMERYIKVIEACCLAPDLLAMGEGKDLTEIGERGINLSNGLKHRIQLARALYADSDCYILDEILSSVDPEIANYIFQHCIKGMMKGKTVILVTHQIQFISSADHVVVVDNGVLIQGTYLELLRMGIDFEMILKEKENRIEKQIVQLQEDEDYYEEVEILDFTMNNNNNNNNNNNNNNSNFNGNNKLKRSSISLPKGISIESIISKDFDQTTIEKAKLFVQEDRNKGDPGWIIYKKYIRMGSSISFFIFTCIIYLTSQIILLLSDYWLQSWASHDRLNVSEPTDVHYLLIYLAYIGGFVFTLGVRYLLIAKITFGSAETLHRSLLKSIIRAPLTFFEQNPVGRILNRFGKDISDIDILLLDCFSDVLYCGACLVTSIGIIIYISPYIAIPFVILIAINYIFQLFYNYSVLELKRIQSISRSPVYSLLSEVYNGLTTIRSFGQQERFFNMMKDNININLRVFFYNFAVSRWIGIRVEFLSAIVVLMSALFSIFNDNPGLSALGVTTALGITFNLNWFMRQFGELESRINSVERVQSYISIPKEKETNEDEFIQTGFIWPSRGEIEFKNVEIRYRPNSIATLRNFSMKINAQERIGIIGRSGSGKSTIGMSLFRMIECSSGSILIDGDDISQIDLKRLRSSIGIVPQDPFIFSGSIRLNLDPFDQFTDNEIWEALSKVKLKKMVSTMPMKLESLVQGGDGLTIGNKQLLCLCRAILRNSKIVLFDEATNSIDFQTTRLIKQTIEENFKDCTILTIAHNIDTILDSDKIAIIDEGELIEFDTPLNLIKDSTSRFSKLIKLNNNQKNKLN", "length": 1436 }, "evidence": [ { "id": "G3MZM9", "url": "https://omabrowser.org/oma/group/G3MZM9/", "database": "OMA" } ], "glygen_name": "Cellular slime mold", "common_name": "Social amoeba" }, { "uniprot_canonical_ac": "Q54VG9-1", "protein_name": "Uncharacterized protein", "gene_name": "", "tax_id": 44689, "organism": "Dictyostelium discoideum", "sequence": { "sequence": "MKSIIILSFILSIISFSNGTIVKCTSASCSSLNNNCVNHYCNPRAGCYGIDKCVRIDACHIVSCDLNNGSCINTKANCDDGDPCTDDFCHNGYGCFSLPNNKHPSVICQKNCNDNNPCTDDFCDFTNTCQHTLKNCEDNDFCTIDSCGPNGCVHTNISCDDNDPCTSDFCSIMYGCYHEQIECSIKVPCSTDIECNRYNLCETYTCDLISNICKYSTKFCNGFPCINNECMTGVIYN", "length": 237 }, "evidence": [ { "id": "G3MZM9", "url": "https://omabrowser.org/oma/group/G3MZM9/", "database": "OMA" } ], "glygen_name": "Cellular slime mold", "common_name": "Social amoeba" }, { "uniprot_canonical_ac": "Q54WA9-1", "protein_name": "Short-chain dehydrogenase/reductase family protein", "gene_name": "", "tax_id": 44689, "organism": "Dictyostelium discoideum", "sequence": { "sequence": "MEIKKNIFFITGCSGIGFGGLMVKKLLSRGDYVAATSRNKNKLIQDIGSNENDQFLPIEMNLADESNVKEAIEKCIEKFGRIDILISNAAMGILAPLEETTDKDARTLFDINFFGPLNLIRNSLPYLRNNQFLKNNNDNNNSKLNGPRIIIIDSICGYSSLFNGCSIYCSSKFALHAISETMSIELKPFNIHCCNIAPGYFQTSFLSSCLIPDTRIAEYKDTHSFLDEIVKLNGSRFLGDLSKAVDVIIEISLSYSPPNHVLVGSDAFELFDLKYKKLTNDILINKEICSNTDKN", "length": 295 }, "evidence": [ { "id": "G3MZM9", "url": "https://omabrowser.org/oma/group/G3MZM9/", "database": "OMA" } ], "glygen_name": "Cellular slime mold", "common_name": "Social amoeba" }, { "uniprot_canonical_ac": "Q54WC3-1", "protein_name": "Cln5-like protein 2", "gene_name": "cln5lb", "tax_id": 44689, "organism": "Dictyostelium discoideum", "sequence": { "sequence": "MNKLIFIIICLGIVDKTISSDFKSYNDGIYSFTYDNICSFKNSIRDQDVYELYYVQAPLLYATYGNLLEKINAYHSGIVLYNKNNGPNITIDYYAIPSFEATLFPKSIIKDSQGNYNITWDTHGLIEVTNYINETYWNKRQLIMYDLSGIQIKQYLSWAPIYNKTHTFYNLFNIESDLSISNSSKIYKNSSTCDDFVWASFDVLYKLGGTIASVQSDPQRDDIKLFISSGEPKIVDYNDSIKRNQIASFFNELKDFANLGKNKTALEIFNELITFFNGYFYCYIDGEYYEMKLSKQNPISFTYLPSPIPIGKRNFNEIKKLGFCK", "length": 325 }, "evidence": [ { "id": "G3MZM9", "url": "https://omabrowser.org/oma/group/G3MZM9/", "database": "OMA" } ], "glygen_name": "Cellular slime mold", "common_name": "Social amoeba" }, { "uniprot_canonical_ac": "Q54WW7-1", "protein_name": "Probable serine/threonine-protein kinase DDB_G0279405", "gene_name": "", "tax_id": 44689, "organism": "Dictyostelium discoideum", "sequence": { "sequence": "MGCIFTKPSPEQQKFDGEDYECENKKNLNLISYIRNLLFGNNSHQQLYNEIIPTTTSTTSTTTNSVYQNIGLDGYNNNNNNNNNNNNNNNIMNNYGYDDYGYSYEEDEDYYDEMPIPTIVAQPQPQPQPQPQPQPQPQQPIRIVSQNQQIPTTPPQQISQFNITGNKSPSSIGSRHRSKPKETLRAHKKRHKDGHKMVNEYVFVRKLGKGTFGKVKLAYHHDTHHLYAIKIFNKIRLKKQTMGIGRPNAFDDVLKEIAIMKKMNHINVVKLYEVINDPQEEYIYIVMEYIEGGSIMSANETSEDLARKYFRDIVFGLEYLHEQKVIHKDLKPENLLVNSEGVVKITDFGVSHIFDDDDVVRCSRGSPAFLAPELCRNESQPISGKGVDVWALGVSLYCLIFARTPFISKTNSLLDIYDQIVNHEPTYPREISNDLMDLFKRLLDKNPLTRIQIAEIKSHKWTTISGTWPMNELDHLILSVTDQEMIDAISTDHTIKPSDNTTTDEDDSDLSSSSGGESSGIIGSSNESKSMYNNVNSKQKIQNQNQNQNQNQNQNQNQNQNQNHNQNQNQNQNQNNNNNSLIEKSNISIPASSSSISNNDSCYENRNVYIKDEEMNMICNDSVIMDPIKELNKIDGLNYGCDFQIGKEYSDFQYNSGHFIYDLVDENESQISRESANDYYLPFKTNKYLNNKSIV", "length": 695 }, "evidence": [ { "id": "G3MZM9", "url": "https://omabrowser.org/oma/group/G3MZM9/", "database": "OMA" } ], "glygen_name": "Cellular slime mold", "common_name": "Social amoeba" }, { "uniprot_canonical_ac": "Q54WX7-1", "protein_name": "Uncharacterized protein", "gene_name": "", "tax_id": 44689, "organism": "Dictyostelium discoideum", "sequence": { "sequence": "MARTDNVQLPLENTSIEFEEEIIDSQNDISQQKNYQDFLKNIPTDLNERKEYISSLKKLIKLEKRNHQQIQGEQPNQQEGLNSDRPPPNHHGDHHHSLPPPNHHGDHHHHSQPPPNHHGDHHHHSPPPPHHHGGHHHCPPPHHGGHHHCPPPPPHHHGGHHHHCPPPPHHHGGHHHHCPPPPPPHHHSHHHHCPPPPPPHHHGGHHHHTPPHPPPHHHGGHHHHCPPSPHHHGGHHHHSPPPPPPHHHGGHHHHCPPPPHDGNEYLPQSQTNIEQCICRLNRKKELLIAKIQSIDSIIYNLECLNKQNYQNNYLPSIQLQPTQQPQQPQQTSIKPQQMCQQFFIPQTPNFPQMNNSAPLMYVSQIPVQQSFNNN", "length": 374 }, "evidence": [ { "id": "G3MZM9", "url": "https://omabrowser.org/oma/group/G3MZM9/", "database": "OMA" } ], "glygen_name": "Cellular slime mold", "common_name": "Social amoeba" }, { "uniprot_canonical_ac": "Q54Y59-1", "protein_name": "Small GTPase", "gene_name": "rsmH", "tax_id": 44689, "organism": "Dictyostelium discoideum", "sequence": { "sequence": "MFNIFLSKSKDVYRVTSHKKEVKICVLGDANVGKTNFINQFTKSSFNEEYTPTIESRQNKLYKFNRKQFQIQIYDTAGSKELNLFVSDSISQCEGFIIVFSLNDRNSILKIQHYKTLIKNIFKDVEMPIVLVGTKMDLKKEITISKNECKITSVNNNIPNLFYTSAKNKESIIPVFKKLVDLIISKEKKVKKETESNNIKINNQNKIKKQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQHVFKTRSNSTLRMKKYLKLF", "length": 272 }, "evidence": [ { "id": "G3MZM9", "url": "https://omabrowser.org/oma/group/G3MZM9/", "database": "OMA" } ], "glygen_name": "Cellular slime mold", "common_name": "Social amoeba" }, { "uniprot_canonical_ac": "Q54YJ4-1", "protein_name": "Uncharacterized protein", "gene_name": "", "tax_id": 44689, "organism": "Dictyostelium discoideum", "sequence": { "sequence": "MKKVYQDEEFSFFEIGGKKIADLYVRDIITEIRKRGKEITGLGLKSKYELLCILVNRMKEENPSLNIPPKKRVLDFGSLSSTTSNGILQDSNKFFKKDNTHQHQQQQQQQQQQQQQQQQQQQQQQQQHSNNSDDDDDTHNYNDDSDESDDEYIITEEEEIELHKNLNLGDDENLLTLEIKLLESQLENKKFRKSLLLKDKKIKHLENIIQQQQQQLLEQQHQQQQQQQQQQQQQQQQQQRQEEEQQKEQQQKEEQEQEQSSLKNNLKFKDGANLFSIESISNLYNKILNEFNFKKIITEFGDSSLKIHEEFVKFIILKSINLNHNNNKNNNKNNNNNNNNNNNNNNNNNNNNNNNNNNNSSNNLPNGDVNKNNNNNGEIIELVPPPKIDEFWKLMVLDTVGYQQFSNILGAKVNYDTDINPTRKGYQRLKDMKNLYFPPPPSTTELTTDEIWPNHYLLPIQPSPQKQHIQKQQLPSSSSSSSSSSSSSSSSQQHQQHQPQHKQQHQLQQIQEQQPQQQQHQQQQHQQPLQQQIQQQQQQQQQHQPQQQHQPQQQQQQQQPQQQQQQQQQQQQQQQQQQQQQQQQKKQQQQHQQQKNKENNKENNKENNKQNNKENNKLNDNNLNIEVHEDEGNRIINFLISPDTPLRNLFVAYAKEIGENFNSFKFYFGNELLCQNETPSQLLMRNGTKIQAFYLNKKEIKK", "length": 702 }, "evidence": [ { "id": "G3MZM9", "url": "https://omabrowser.org/oma/group/G3MZM9/", "database": "OMA" } ], "glygen_name": "Cellular slime mold", "common_name": "Social amoeba" }, { "uniprot_canonical_ac": "Q54YV1-1", "protein_name": "Rho GTPase-activating protein gacII", "gene_name": "gacII", "tax_id": 44689, "organism": "Dictyostelium discoideum", "sequence": { "sequence": "MVRKLFNTSHKKELILDVDTTIVKIGTPKNVVLLTKWLDANGAIKEEGVFRVNGNTTTMEQIKKNFSQGKDDLTKYTSADIHSMAGCLKFILRELPEPIFTWDFYPIFIKIQCLQDESRKLFFLKMLIHGLPYTSRTLVFQLFGFLSKFSVHQDQNKMTPKNLATVFAPNVLRPKKEEDNFQLMNNQDSIGVIETLIEEFQYISNIQKNTLNSQEIKVKSVLPFDETTNAITQQSLVEDYLIAKANTPQESSSFKKNLPFKKGDIIKLLYIKNDGNFIGEINGITGNLSQTYVDIIDISELAEAFTLTPPPIPTLPIASTILHTPPTSSSSSSSSSSSSILLTDNQPKLCSSTPRINNSPSSFSPSLSSTTPQLLVQQSPRQSPRQIPSISLIVEPNNTNQPSFGHGTLQRTSTGYFSSKPLSISQPINMSKPTNMSPPTHHAMSMHNLPPSNTTRENHLPPLPTKPPPLTIPSSSSLPTTPIKQQPQQPIQQPLTPQNHHHHHHHNNLSSSVNTANTGNCANILSPNSDRYLSSRSQSSVHLSGSSSSSSSSSSSSSSSSSSSSSTSNRKFDFSLKSKSSKNSPSKNLPPQPTTTSTLTPPPPPTITTTTTTTTTTTTTTIATTPPPPSKPLPNIPVKDQQFNTLKRSTIEIPPPTITSTNINNNNNTINPRTLNYSFSSFSITYNNSQLGGQLSQEEPPGGVKSQSSYLDNNNLPSRNTNIPNLPPRPPPLNIPQQQQQYKPLPSPPQLQSPQSSLNQSLQIPLQQQQQVQQQKLTTHYILPPQNTNLSGKNLQRSSTSMLLNKLPPPPFSFNKN", "length": 817 }, "evidence": [ { "id": "G3MZM9", "url": "https://omabrowser.org/oma/group/G3MZM9/", "database": "OMA" } ], "glygen_name": "Cellular slime mold", "common_name": "Social amoeba" }, { "uniprot_canonical_ac": "Q54ZA1-1", "protein_name": "Reverse transcriptase domain-containing protein", "gene_name": "", "tax_id": 44689, "organism": "Dictyostelium discoideum", "sequence": { "sequence": "MIKIMTWNCQGCSTIKSMNQTKNTINLIKPDISILTETNLKKDQNLAQIKNHYSTGGKGKEARGKGVMAINHLEQIEIKNLEEKEGRILKFTAILNNMEINIICIYAPASYDRRKGWFSNNISLEDLEQADIVTGDFNINKYAKIKFKDGSSDKRKFTENETIEFLMMEVGLTEILPNSTTKTTFKDKLIDRTFLSTKMHQLNHSYKIIDKINKSDHNIVVMDFKIPNFTKIYKSPLWKMNSIIIKEDKTIKKIEKIIDHYQETKRKNLNITEYWIKFKKKIKKQCITTEKKRILERKKTLSNLANEHTKTKNKYEKETISNEITILQEEERIDRMIKSSINYINNKEIASNLLTSILKKRDSGSQIHRIKNPSNGEIETEQKEITDCFRKYYETLFKEKECDQETHTELLSTWNPPIDKKKLTEMEDRIEEYEVKLAIEKIAEGKSPGEDGITSSFYKIHQHKLIPILTELFNFFLNNEIPTEFKNGILTSIYKGKGDVLEISNRRPITLLNVDYKIYSKIINNRILKILPNIISKYQNGFIPGRLLHNNIIALDLAMEKSDRNTIITFYDFEKAFDSISHKALIRTLNHLKFPRKITNTILSMLTNTNIRVMVNGQLSESFRAGRGTKQGDPISPTLFAIVCECLSTSIRKDNTIIGIKLNQNNSMKIGQYADDTVTLASNIDDADKMDMKVIKFCQATAAKINDNKCVCITKNPKIKTKYKTIGAKEEERYLGFFFNRKGVISKVDDTVNKLENLTKCYSSVSSTLKGRITILKSYLLSQLTFQLYINEINDIKKLENVNANMLFKGDRWAISKERSRRDYEIGGLELWNMATRSNAQKAWIYEQYLREKDDQNCPPHMEVWKSEKENSLSRIHIKCWKAWKLLHHPRERITLKLNQVKPKYENKQKLKVIYRNMMDIKYKGWNKHQPTTGQKLIQKNINHPILPFREARSITTIKGRDLAWRYLLKALPKHHGENCHSCKEEESSMHIFFECKSIKQNIDSIYQKVCKDSNNTYHGPWSEKVLGKLLTPFSSNLIGAIMESIWYRRNQIKFNDNTTIITENQIIHKIKKARDAEWDRTRKIVEKQLRQELRCTDNRESINRTASIKRRLEKFSHNWNSKLMTINIPEHFIPYCSYNTNYS", "length": 1144 }, "evidence": [ { "id": "G3MZM9", "url": "https://omabrowser.org/oma/group/G3MZM9/", "database": "OMA" } ], "glygen_name": "Cellular slime mold", "common_name": "Social amoeba" }, { "uniprot_canonical_ac": "Q54ZA6-1", "protein_name": "Alpha/beta hydrolase fold-1 domain-containing protein", "gene_name": "", "tax_id": 44689, "organism": "Dictyostelium discoideum", "sequence": { "sequence": "MEKINQTPKKHKIIEPNRKGYSIVGKNTGKPNKIYFETFGNGPKKILFITGFLSSSKGWCKQIDYFTNKKDQYEICVFDNRGIGKSNIDSKYSYNFSTKSMAMDAIDLLEDTLKWDKVHICGLSMGGMASIHLSSIIPEKVQSLVIACVPNGYFLPFFSMGVFNYIRAFFFTFNEKKKARIFQSLMYSDNYLDEKTNGSDETRSEQMFKKNSTGFKDDGPSFLTILGHQIGYITNRFSKKSLEVIKKYSIPTIVINSKKDSLVTIDITKKQIVNPLKPLNFHVIEGGHLSQLENPTFFNKLVENHVDKHSNWDHSTFFQVEKQQFQRQSFMTQNILYSKNYLSSNTLSSSFLNCNTLRSFFNKIKV", "length": 366 }, "evidence": [ { "id": "G3MZM9", "url": "https://omabrowser.org/oma/group/G3MZM9/", "database": "OMA" } ], "glygen_name": "Cellular slime mold", "common_name": "Social amoeba" }, { "uniprot_canonical_ac": "Q54ZT3-1", "protein_name": "Reverse transcriptase domain-containing protein", "gene_name": "", "tax_id": 44689, "organism": "Dictyostelium discoideum", "sequence": { "sequence": "MIAKTQIKCTTIYAPAKSNERHEWYKENLTEEILHSDIITGDFNVDCSVDNNLNKYIKTIFDEFEFTEIKNGITFPRNKSTIDRVFVSKKILHLNPIVTTKEIKLKSDHNMVIIELKIPEYEQQKKGERLWRQNLETLKMNSTSLKINKTIKYYNKKFEENTSKWYKLNICEQWLKLKDEIKKLSINIEIRESNKTKNKLKELAEKLETAKDSRAIFLKEEINNILKEQVRIKQANQTNTHINNKETPSKYLTRRLKVQRKTNEIPQILDPSNNCLVTKNEDILEVARRYYENLYQKRECNEDTHHELLKTFNKRIDQKILDEINQPIEGYEIRLGIEKIQEGKAPGKDGLLPTFYKNHINEILPIISKLYNHFWNTTIPKDFKQGILITIYKNKGDPNNLDNYRPITLLNVDYKIYSKIINNRILKFLNKIISPFQTGFVPRRLLHDNIITLNSTIEIIKREINTKEDMEPIITFYDFEKAFDSISHNAILRTLAHLKLPLKMVLTIMNLLNESETSVYINNSLSKSFTSKRGTKQGDPISPTIFALVVECMATTIINDRCINGVTKETIKILQFADDTATIAYNFMDHFLMNEWIKKFCQATSAKINQTKCSCITFKWNTRTLYTVIKSNERYLGFDFNNKGIKSKINTISDNIRAKLVTWNSTSSTYMGRLIMAKTYALSQLTFHTYINTTPQHNSIENNIVKFVFNTKSKNSLSLQRRQNNYINGGLNLWNLKTRELAQKAWLFERYLHQRVSNTPSSYIKLWEEELKNNNNNKTTTKQNQLQLHWQCKQAWTQLKTPQNKQTHYEHLPKLKKIYEDMMTTQSPEHNKFIPTPGQKEIMTKINSKHLPFKEIKKIINMKGRDLLWRYTLKALPKIYNMPCQQCGEDETSEHIFFNCKAHIKNTQEIFNYTLTKSGHTTHTWNVKILNHLQIALVANLIAIIFDKIWHKRNKLIHDEKEIIIHRQQVIRELIKTQRAAWDRTQAVINKTLRIKSKQRPEEQNKLDSLISLKLLQFSRQWNSPLHAIELPKHLKKYNNSLSTFYK", "length": 1047 }, "evidence": [ { "id": "G3MZM9", "url": "https://omabrowser.org/oma/group/G3MZM9/", "database": "OMA" } ], "glygen_name": "Cellular slime mold", "common_name": "Social amoeba" }, { "uniprot_canonical_ac": "Q551H6-1", "protein_name": "t-SNARE coiled-coil homology domain-containing protein", "gene_name": "", "tax_id": 44689, "organism": "Dictyostelium discoideum", "sequence": { "sequence": "MATRDITSSYILSRTECKNRAKIINSAININIKKSGSGYKRLEEENYQDIDIDNNNNNNNINNNNINNNDNDNDTTNNIKNSNNNNDIQLNILDTEINIEQLNSLPPWILKLNDIDENIKKIISLIEKFKKYLKEDIDKILAEDIEMESRIDCERSIELLTMETIRLFHKTFDMIKYLNKSNNSSQGENKMKKNTQRMKSAKLKALLITFKHIQRSYLALLKKVSSLQRSLSSSFLYRSGEYDVNNDNEDYGENSSISNSHYLQHHHNNNHHHEDDHDHEEDHEEIMDELNEMATTLIERQRVSQLIKETSHLIQDVGSMCVKKDSIFDRIDYNLAEGEELEFNGTILICDGITNGYERPENEKRKKLLLIFAVLIIVILFIFILKYVIEI", "length": 391 }, "evidence": [ { "id": "G3MZM9", "url": "https://omabrowser.org/oma/group/G3MZM9/", "database": "OMA" } ], "glygen_name": "Cellular slime mold", "common_name": "Social amoeba" }, { "uniprot_canonical_ac": "Q551V5-1", "protein_name": "EGF-like domain-containing protein", "gene_name": "", "tax_id": 44689, "organism": "Dictyostelium discoideum", "sequence": { "sequence": "MKYLFRFFIFLFCITRINSQTGCFFRETGADYNIDSVFSVFYVDNLFNIFGMTFYMKTCTYVTCDPWRQTMICGNYNSTTFQLGPYQSQKVTLNKNGISIEYLSDKTPPNHPCPTITTTVKFICDKSVLSVPKSDYDYVGTCGVQIKLFAIDYCQTCSKCIASHGSCNSTSGWCTCDSYTMGLNCDQLKASISSVVAPTIDGGSVIISGDFSSIYSLGPSLVITIGSLVCSQVSFAASTTQISCTIGAGQGYQNLTISDGSGSTLQYKQFYYHYPCQEDCTPYGTCNDVIGKCTCNYKYSIGADCKTLNLQLTSVKPTLLDGGQAYLVGDFSNVTGLTLSVKIGIKECTDVNFNETTLQCTIGSGEGIKDIIITSDLLTYSKIGAYEYQYYTCPLGCLHGTCNKYNGLCVCNNGTYGDQCQYIECPLDCSTPNGVCDKDTGICDCDDKYSGEGCDFIKCPLDCSTPNGVCDGKTGICNCDEKHSGDSCQFLQCPLNCSNPNGICNRNTGICSCDSKYSGEGCDFIKCPTDCSTPNGTCDGKTGTCKCNNPYTGENCDEIAKCKQECSLKHGTCDSHTLDCICDTQTKGLSCEESRLLIESADPTSLDGGTTTITGYFGTTTSLLSIKIGDSQCTNIKVESDTKLKCDIGPGEGTHNVTVTDDDLSFTGVGMFQYVGQINKISKISGGAIAGIAAGCVVGVSVLGAGGYYQYRKNKKIELFMS", "length": 722 }, "evidence": [ { "id": "G3MZM9", "url": "https://omabrowser.org/oma/group/G3MZM9/", "database": "OMA" } ], "glygen_name": "Cellular slime mold", "common_name": "Social amoeba" }, { "uniprot_canonical_ac": "Q554Y8-1", "protein_name": "ADP-ribosylation factor-related", "gene_name": "arrB", "tax_id": 44689, "organism": "Dictyostelium discoideum", "sequence": { "sequence": "MGMGFSFIEKKDFKRFLILGIDNSGKKKIMYRLKFNKDIPTRPEKGFFVETFERRFKYNNEDVCGQNMIRPLWPNYYTDETNGLIFVVDSSDQERIEEVRLEIKKLDENIKIFKNHPFLIFANKQDLKNSLSIEQLIDKLELNKLSLNRKWHIQSSNAITGDGLEFGLNWLFSSSHNFT", "length": 179 }, "evidence": [ { "id": "G3MZM9", "url": "https://omabrowser.org/oma/group/G3MZM9/", "database": "OMA" } ], "glygen_name": "Cellular slime mold", "common_name": "Social amoeba" }, { "uniprot_canonical_ac": "Q555E8-1", "protein_name": "Putative fatty acid elongase DDB_G0274669", "gene_name": "", "tax_id": 44689, "organism": "Dictyostelium discoideum", "sequence": { "sequence": "METVQSIITEWTDPKSWEKLVQHSFKDSNWKELIDPVNYKFNFGVTPFSQFQIIPIVLVIYLVTIFSIKFLMKNRKPFSLKFISILHNAILCIWSLIMCVGVLYEIIKRVSNEGPLFTVCEDPNGGFDKGVTYYWSYIFYISKFYELLDTVIIVLKKKPLIFLHVYHHCKTVWWKKYITMIQILQFVCLGIAGVLHVYTINTIGCFTHYPAFAAAYSINFSFLFLFSKFFVKSYTPKNSNSNTNIKSKKID", "length": 251 }, "evidence": [ { "id": "G3MZM9", "url": "https://omabrowser.org/oma/group/G3MZM9/", "database": "OMA" } ], "glygen_name": "Cellular slime mold", "common_name": "Social amoeba" }, { "uniprot_canonical_ac": "Q555Q5-1", "protein_name": "Reverse transcriptase domain-containing protein", "gene_name": "", "tax_id": 44689, "organism": "Dictyostelium discoideum", "sequence": { "sequence": "MRSIRIKKINFHIKQGEEQLKQELNNYCEETSLKYISARIKKRHNDFTINAVKDAQGRTINKQELIEEEYVKYYSNLYDYKEDDAPSHYEMLENWTVTRDSTWDNLENEFTTQEILEVIKQLNPHKSPGPDGIPNLFYITHKEKLAPILASAFNDTLRNPHLISKNYKEGLIITIPKKGDPELIKNRRPITLANCIYKIHSKLINNRIIPILTKVINHNQKGFVPGRFIIDNIISMNELINYCNDKRINGIITLYDFEKAFDSISHGSILRSLQHINIPTNIINLIMNLLTKSEARIEINGRTTIPFEIKRGVKQGDPLSPTLFVLVIEALARKILQDDRITGLPLNNSDHREKFQSFADDSASMVPDSQQLELVLQHFNSFCKATSSKLNIDKSSSILIGNPDNTNQRIPISTNPERYLGYFFTGKGITRKIPEILNTIRSSLVLWKTTDSTIKTKTNILKAFALSKLTYYSYVENFKEEELNQINKLVEWFLSAPNTKMLVDFKITPKLSPTAKKDQEVNADYANHRFHKEYFEWNYKAIDYDLTRSFAYRNLMALILHNIWIWICNQIYSEDPLTDESLSYSSLLKKWHKLATLEYIKKAKDLKNLSAKDHNNFKDPKILLTSTIKLRKTTANYYCIPESSLPNIISFDQFI", "length": 655 }, "evidence": [ { "id": "G3MZM9", "url": "https://omabrowser.org/oma/group/G3MZM9/", "database": "OMA" } ], "glygen_name": "Cellular slime mold", "common_name": "Social amoeba" }, { "uniprot_canonical_ac": "Q556H5-1", "protein_name": "Cofilin-3", "gene_name": "cofD-2", "tax_id": 44689, "organism": "Dictyostelium discoideum", "sequence": { "sequence": "MTTPKPTIAKISPECQTHFQDIKFRNKYQGILLKVNEESNMVVDKTLVAEGEFSELAQSLPTDQCRIIIYRYKSGEGSKLFFIYWGPDSAPQQDKLIYGNAKVTLAITLKGIDHKISASNLKEISEQVFIDRITPKTA", "length": 138 }, "evidence": [ { "id": "G3MZM9", "url": "https://omabrowser.org/oma/group/G3MZM9/", "database": "OMA" } ], "glygen_name": "Cellular slime mold", "common_name": "Social amoeba" }, { "uniprot_canonical_ac": "Q556J5-1", "protein_name": "Uncharacterized protein", "gene_name": "", "tax_id": 44689, "organism": "Dictyostelium discoideum", "sequence": { "sequence": "MWNHNLCHAINLDRQFDHINNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNKNNNNNSYDYSFSVHSSQQYSRHYPNSCNNEQTKPKDYYDHASRSQHDYHANGSNNGNNNNNNNNNNNNNNNNNNNSNNNNNNNNNNNNNNCDSNYNSNNNNSNNISIANIKYQQDQHYQHSDTYTSHQYNSFNDNNNNNNNNNNNNNNNNNINNDNDNNGYNQYDESEEDEEEQDDYDEFDIQDSASSYNDNCGVLNSNTYIYDYQSPQQPLYSNEYQNNNHQPQQTDSYNYNNTNNDNNSYNINNNNNNNSYNNNNNYNNSNNNNNIGNIDSNTNNNNYNYNYSNNGDVYNGYNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNMNNMNNMNNNIITSNREQFYSNNNHNNINQYQYQSQQQQTQQQQQQTQQQQQQTQQQQQTQQQQTQQQQQYLTQYYQQELYSQSYKCRPYYQNSFVISKC", "length": 480 }, "evidence": [ { "id": "G3MZM9", "url": "https://omabrowser.org/oma/group/G3MZM9/", "database": "OMA" } ], "glygen_name": "Cellular slime mold", "common_name": "Social amoeba" }, { "uniprot_canonical_ac": "Q556P1-1", "protein_name": "CWH43-like N-terminal domain-containing protein", "gene_name": "", "tax_id": 44689, "organism": "Dictyostelium discoideum", "sequence": { "sequence": "MISSSLKPSVLLWILAILIPSTLITTYTLTVLLFHGIRRTVPYISDTIDFSPESCIGTFFISISAFLVFIVVFVKHFLLQNNINQNFNIDIILNENENEKKKNRAKMLNRISTFLGLICGVCIHGVSSFQYHNTGLVHSIFAASFFFTGFIYIFTQTYLDHKFSKLPKRILILRRVISLTTSVFIGYIILQFFIDNLAPILKIISALSIFFYLISFFYEFSKITINFQINTISQIEHQKEYNENSALLISQ", "length": 251 }, "evidence": [ { "id": "G3MZM9", "url": "https://omabrowser.org/oma/group/G3MZM9/", "database": "OMA" } ], "glygen_name": "Cellular slime mold", "common_name": "Social amoeba" }, { "uniprot_canonical_ac": "Q556R5-1", "protein_name": "Reverse transcriptase domain-containing protein", "gene_name": "", "tax_id": 44689, "organism": "Dictyostelium discoideum", "sequence": { "sequence": "MFNFERIDHGSGKGTGIAIENRDTRKGHISINFKDDDGRILSIKYNSFNSINILLINAPATISERNTFIINSKSLFKKYNSINHQIIAGDFNNNHDCNSFFGTELRKIIDQDMLLDTGIEENTPTFPRSMKRLDRIYCHPTLLNQNSKLVVHNTVFNKSDHFPITITIQTNRETTTTTTTTKLERLPWTLCKEILNNKHIHDGLSELISKNKDKIKSVEEWTKFKNNVIRDYLKKEQNKIKKEKNKRKYVIHKLLGNSDIIPKMRKELNEEISRILEEERKVKAWDIKLKLHLHQETPSKYLTSILKSRAKDKSIFQIKDKDNKTISDKENIAKRFVEFYQDQYEEKEDNEETHKKLLEKWEVDVDLIKKLEIDRPIRIHEVTKAIKTSSIHKSPGLDGINALFYKYHINSIARILTIAFNDLLTNKKEIPTKFKEGVITTIFKKGDELNISNRRPITLLNTDYKILSKILNSRLLDITSKIINKFQNGFVPNRFIQDNIQIMKEVIEISNKRKNNTLITFYDFNKAFDSISHKSITRTLEHIGIPPKFTAILLNLLKDTKNKIKINDFLVNGITIRTGTKQGDPISPTIFALVLEPLLIDIINDNTIKGFTLPNSKSLKLTAFADDIATFTNSTEELMKINTKIQKYCSATSSSLNKEKTVMIAIGDKPHDLPFQESTVPERYLGLNFTKTGLNSKYNTLIQEMKNNLIKWKSQAITMKAKMTILKTYVLSKLTYHQYMDNLNEEQIEEINNMTRWFLFSSVKNTYTEERKYKTMMKIDRAYADWKEGGIKLWDIELRHIAFKIWYMNRLLHNNYNNNNNTLQEWYMEQLSRKKPTLQPSTICADTGVYSESNFTKTIQR", "length": 861 }, "evidence": [ { "id": "G3MZM9", "url": "https://omabrowser.org/oma/group/G3MZM9/", "database": "OMA" } ], "glygen_name": "Cellular slime mold", "common_name": "Social amoeba" }, { "uniprot_canonical_ac": "Q556X2-1", "protein_name": "Reverse transcriptase domain-containing protein", "gene_name": "", "tax_id": 44689, "organism": "Dictyostelium discoideum", "sequence": { "sequence": "MIAKTQIKCTTIYAPAKSNERHEWYKENLTEEILHSDIITGDFNVDCSVDNNLNKYIKTIFDEFEFTEIKNGITFPRNKSTIDRVFVSKKILHLNPIVTTKEIKLKSDHNMVIIELKIPEYEQQKKGERLWRQNLETLKMNSTSLKINKTIKYYNKKFEENTSKWYKLNICEQWLKLKDEIKKLSINIEIRESNKTKNKLKELAEKLETAKDSRAIFLKEEINNILKEQVRIKQANQTNTHINNKETPSKYLTRRLKVQRKTNEIPQILDPSNNCLVTKHEDILEVARRYYENLYQKRECNEDTHHELLKTFNKRIDQKILDEINQPIEGYEIRLGIEKIQEGKAPGKDGLLPTFYKNHINEILPIISKLYNHFWNTTIPKDFKQGILITIYKNKGDPNNLDNYRPITLLNVDYKIYSKIINNRILKFLNKIISPFQTGFVPRRLLHDNIITLNSTIEIIKREINTKEDMEPIITFYDFEKAFDSISHNAILRTLAHLKLPLKMVLTIMNLLNESETSVYINNSLSKSFTSKRGTKQGDPISPTIFALVVECMATTIINDRCINGVTKETIKILQFADDTATIAYNFMDHFLMNEWIKKFCQATSAKINQTKCSCITFKWNTRTLYTVIKSNERYLGFDFNNKGIKSKINTISDNIRAKLVTWNSTSSTYMGRLIMAKTYALSQLTFHTYINTTPQHNSIENNIVKFVFNTKSKNSLSLQRRQNNYINGGLNLWNLKTRELAQKAWLFERYLHQRVSNTPSSYIKLWEEELKNNNNNKTTTKQNQLQLHWQCKQAWTQLKTPQNKQTHYEHLPKLKKIYEDMMTTQSPEHNKFIPTPGQKEIMTKINSKHLPFKEIKKIINMKGRDLLWRYTLKALPKIYNMPCQQCGEDETSEHIFFNCKAHIKNTQEIFNYTLTKCGHTTHTWNVKILNHLQIALVANLIAIIFDKIWHKRNKLIHDEKEIIIHRQQVIRELIKTQRAAWDRTQAVINKTLRIKSKQRPEEQNKLDSLISLKLLQFSRQWNSPLHAIELPKHLKKYNNSLSTFYK", "length": 1047 }, "evidence": [ { "id": "G3MZM9", "url": "https://omabrowser.org/oma/group/G3MZM9/", "database": "OMA" } ], "glygen_name": "Cellular slime mold", "common_name": "Social amoeba" }, { "uniprot_canonical_ac": "Q557C9-1", "protein_name": "Homeobox protein 5", "gene_name": "hbx5-2", "tax_id": 44689, "organism": "Dictyostelium discoideum", "sequence": { "sequence": "METIVNNQNNGQQNTVPTQSFSSSVYMNYDFFDSQQLQQPQHQPQHYQQQDSFVSPNLDNNNPQIHVQSNNYNQNGFVGYNNSNNNNNNNQHMNNQYSNSFHNNNSSGFMAFQNNSSNFNNQNNNNSNNNNNNNNINSYDYNNSNNNNYNNNNNTHSNNSNNNNNNNNSNYWNNNNNNNNNNNNNNNNNNNNNNNNNNNNNSNNNNNNNNNNNHHHHHHQQQSQPTSPYNNPIQHNPNDMKFNGQHNPFNGNQMVMDNNNNNNNNNNSNVFNSNSNSNVFNSNSGSFLQINNNNGSFSSYNNNNNNNNNNNSNSNNNNNNNNNNNNNNNNNNNNNNNNNNNNNSNNNNNNQFSQSYDSTLGNNRFSSMMGQPIQQQQSPPQQQQQQSFIQSSPQAIPASNCNGNGSTSSSTSPLSPTLIGSAPGTPTSMLATTLFGFNLSSSPTSSPSSPVKKGKSQSALALSSSGGSGGSSGRKKPQKHDSMSSITNTNLKSTQASTLKESKRSNSSPNLKKQMQLQQLQQQQKLNENGTLIPPLPFASISENITNNNNNNNNNNNNNNNNNNNNNITNNPLSGSMEFPNSNNINQSSDSINGEFNIGQPESPKMYNSSPSPPPNATSTTKGGKKSKKSLHISTTQQSPSLNGSTGGSMLTPTMSGLSLSGGGSGGGFSPLISPTGTTSNKDLQSSPSPSPLLKSMSMGKLDLQDSIDSMSSPLSPNSSLSSSNGLLPPPPNSNNMNSSGGIPTPSTPTSPPPLTHHINIFSNLEFVKQLKDHLLPNDFKPEEHALERNLLRFQQFVKTLAEPLQRDVVTSMFELSVDAQLQYGSNLDNDNLSALMLFRRKILNFNLFRMMMLNDPNSFIPLPSPFPIQTTTISSNGTIVNPTNVNNNNINNNNNNNNNNNNNNNNNNNNNNNNNNNNTTTTTTTTTSANTVQSGTTSNSNLVFQQTSNSNTLSPSQQQQQQTQQQQSINGSSTGSLSDAQYQDLGIHLDTSSANSGCGINVSIGSSIGGGGGGSSLNGSNLNGSSSISGSISGGSSNGGGQFIMSPQFSLDGAYQQQQPSSYNINNEMELAEKDEDEIFNNNNKDNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNSSSINSNINNVNNCNINNNSNSNNGSINSPRPSTPTTLNSSGKRSKKIYRGDSFGAGNDISTGLMASSDQIIPPPQQQQHQQLVNNNNNNMNNSENNILLADSNKGLSVSLGSLPTNTPSSMEIEQQQQQQQQQQQQQQQQHLNQQQILHQQLHHHLSSSLGGAQFTNIQQQQQQQSGNIFYNSPYNSSQVYMNPYGTSITNTSLAGPSTTSSAMQHMITNMTSSNIIVNNQNNNNNDQNNNNNNNNNNNSTTNSNVNNNNNTTNTPSSPPQPNNCTPTQTSIITSNGVVVPSLQMRGTITNPPPVLPTPDTLVLQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQETPHTPTSNSISSPRSSPVHQQSPSNTNTTTTSTTTIRHSAVTQLSFAGLHNQQVSPISPRSPRSPHGTSGDYNDGSQSPSSRRKNRFTDFQIKRMNDCFENLDKNNNGKFTSEEICQIATELGLTDQQVRVFFQNKRARSRPSPRGQPTNPLTSSTNNGNNSNLALQHLQQQHLQQVQQQQQQLLQLQQQQQQQQQQLHQQSANTTPQLNSMNPNSINYNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNIINNNITTINE", "length": 1723 }, "evidence": [ { "id": "G3MZM9", "url": "https://omabrowser.org/oma/group/G3MZM9/", "database": "OMA" } ], "glygen_name": "Cellular slime mold", "common_name": "Social amoeba" }, { "uniprot_canonical_ac": "Q557D0-1", "protein_name": "RING-type domain-containing protein", "gene_name": "", "tax_id": 44689, "organism": "Dictyostelium discoideum", "sequence": { "sequence": "MTGSNNLNSLNNNNNNKISLQETIQDIIKCSICLNSPKNPRFCPRCSALFCLECIDRWIISNPTCPACRDTLTSDNLNSNLIVSNILNELVKSEQEEYTSSDICNYHGYERLYYCSTCQEPICSDCALFKHKDHKIEKLSINFNKNLEILKIEEEALKKRQEELIELNSFLELDAETLLKNKSQIEKEISKVVITMKARLKYDFERRYNTILESQEKINNELTHLDFIYNDLLNHYKKSPSSFVLTSQQFIGVLQSVHKNSIMDIYTPINTDLTSELIPPFENRLLKFENFTTGDCLFSSRIAFYGMTWEIKCGIEEDNCFLNLKVLECNSDGKYFYMFTIVNQKTNVNKLIEFDLPFQAGETFYIPNFSSKQTLIDEGFILPENDILLLQFSFRPQNYFCYSNDLKRYIDILEYRHRGYFGEEDEDDGTIETTVTKLPNDKSTILGSDNYNDNYNDDGIGDLDEDEEEEEDDEDDDDNLDDHLQYDNDDDEDEEEDDEEQNEEDNDEEGTNIPTSEYEDLDTSSASVISNINRRDRFKNNNINNNNQFVNSNNNNNKYNTTNSNNSIVGSSRYINNNNNNNNNNNNNNNNNNNNNNNNNNNNNYILNRSYSTNKIYNFYQDEEEEEEDDDSNIDDQDEDEEEEDSEEESSLSSSDLQDLDSSGDQSSLEFSFSKYTNNYYSNNNNNYNSGGGGGVGGAGDNNKIECIRRDFNNLLKRINFTNSQLTNLKPGVPKDGDLLNDDENDKKCNIPLNEDEEEDEDEEDDVNKNKTTSTTTTTTTATTTNEVVTINPNTISNNSQDEEEVKSDIVKLLENGIANMLNNSNSSNRSSNNLKQQQQQQQQLQKDDQKQKDEQQNKSNTGCDIDQLNILSKLSIKESCDSIKNNDNDSLGNSTNNNNNNNLNNNNNNNNNNNNNNNNNNNNNNSNNNNLQSFLQSNENTENETDFNDNNTNPETNTETENEYLTSSNMNLDGGESEFDSNKSYEGSSTDENFNSDEDYQDEDNFNQDATGSESANNDDYLDDNEREGSDSIENYDEDIEKVLTSHNIITTPSIPPSQQPQPQLQTQPQTQPQSQPQSQPQLQPQSQPQPQTQPQLQPQLQPQLQPQLQPQLQPQLQPQLQPQTQPQQQKKYDDLSENQIQTENRNKKIKEEINNKTNNDNNNELGKSSKSNTSSSSSSSSSSSSSYSESESSESDSNNEYDNEDEDDIVNQVSNFNFNFNDASNFKNFSFRPKFPSDENDNDDNDDDYEINIDLKNIQKISPILRAIENGESNINHYQSPVSLSSSSSVSSFSGSGNSVPITATTTTTTTTTTTTTTTTDDDSGINMPISPLSASPPSPPPQNEPQINNETNDNDVKLPQI", "length": 1364 }, "evidence": [ { "id": "G3MZM9", "url": "https://omabrowser.org/oma/group/G3MZM9/", "database": "OMA" } ], "glygen_name": "Cellular slime mold", "common_name": "Social amoeba" }, { "uniprot_canonical_ac": "Q559A9-1", "protein_name": "Probable polyketide synthase 13", "gene_name": "pks13", "tax_id": 44689, "organism": "Dictyostelium discoideum", "sequence": { "sequence": "MENFKYRNNENDVAIIGIGFRLPGCKNFTPNELWNNLKNGFNGVVELSNRWSDNFYTMGKVSSAYAGLLPFDELKSFDPLFFGINPTEVPTIDPQQRILLKCTWEAFEDAGIDPIKIRGSNTSVFIGTSTNDYQRIIREKDQTITNAFGTSLHATSNRISYCFDFRGPSMTLDTACSSSLNCVKLGYQSIRDGTSNLSIAGGVNLIIDPYFTASISDLNILSKTGSCKTFDASADGFARAEGSGIIVMKNLKQAMIDGDKIYCVIKGASSNVDGGGLQDKSNFYAPSSLSQCNNIKMALKSTNGTVEPKDISYFECHGTGTPTGDPIETRGISMVFNDESRSKENPLLIGSIKSNIGHLEAGSGIASLIKCCLMFKNKCFAPNINFKVPNPKIKFEEWNLKVVTEPIQFTKSNTCIGLSNFGVTGSNCCLILSQFNNNNNDNQIVGNNNNIKSNKEYLIPFSSNSVKSLENYQQLLIKNGENEFKFLEFIKHQIFTKPTSLYQRSVVIASSWDQFNNAKIMKTSNSKSSNISIERNNPITVFVFCGQGSQYDRMGLELYNNDFIFKESMDLLDNKLSKYYGYSVLEKLRNCDSKSIQHPMIAQPVMCMFNISLFELYKHWGIEVSFIIGHSLGEIPAAYCSGMINIDTLCYLIYHRSIAQTKTHTNGRMLSINISADEYFSQYSKQYPDIEIACFNSPTSIVIAGNEQKLNEISEILKEKGIFSAMLASLSSFHTSSQNKVKEDIVNKQFDSKQSEIPIFSTVTTNLFDSVTSPFNSSYVFNNIVSPVKFSQTISNLYKHIESNQLGNDIVFIELAPHPTLQFYLKQMIPKPTNDDNSIEFKVSVYSALNKKNNDIEEIQRTISQLYCDNGYNVNFKCQFQHDDTHGSINSNINQLSNISLPHYQWDDEKYWKEDPSISKLIVNGPQTDNLGYLNENSPNSKSYETFIDIKRPPFQYLKGHMVKGKYYFPGCGYIDNLLKIYKSQDLTINQMGFKSPLIFIEGVNQALQTNIFKKSTSNTTTNNNDEFRVEYHFNDQKTNRWILSSFGDFQLSNHSSNSDNLEKINIKQLIQNQCNLTKLSRDELYSHIKSKTGLTYNGVFQGVNKCYLGENCSLSEVSLELKREPSSFFNTAVLDTCLHGMLCLLEEQSQLVFDRIEGFKYHSSNVPTSEEEMKIHSNIYVYSTINPSRIGDSYSASIVIMMEDGTVLIEIENAVCTSLTPIKESISVKYPTNQLFSMYLQSKDSPIPSPLNFKSLYNQNQQQLKIDKQFTDWMQKCEKFISNQFFKNIEKRNPEINLEILNSKTIIELKSKYCQNLKNERLFQFVFETIKQLGVNAYDDDDDLTIDSSEDRKSIYEILIKSTKVIPKLLFPLEDEDLTIDSPQSLFENGLLDRFYNNPNLMTNQCQLIAQIIKESLKPLLNKKMVFRILEMGGGTCSLSVVVLNLINQLLLENPSFEIDIEYTWSDISPSFISAAKEKLSHIDKRINILYRSIDIEQPFIEKQDLSPSYYDFVIMSNVLHVVKKLSPSLDEIHKILTPNGHLLFVEIPYKELISDSIFGAFNQWWAFEDTDIRKDRCSIPPNQWIQVLSNHNYKDTIVSDNKECTWCCFVIHSQKPSLLELSKKIECNQYDNIIVFGNENSQDNFTKSIKLSYNNNIIKWVSNIVEIKKFIKLNIITNNSIIYFTKGIEELTIDNFKLINFQYIQINQLLLKYESKCKNVLVTRDCDGSNYLASSLIGAARYFDEYRQLELFTLDFDNDTIQSCDECSSSSCSNLIKLIEPLIDPKINIQREFLIRNNRVYFERAKLETNLKKSFKSESFENSNKLISTLNFNLDYQLQSKPFKQLLQNEIEVEIKATGINYRDYLVFTGSLPIEKTNHNGISNQPEFGVDFSGIVTKVGGGGGNGEFKVGDRVYGIGHNTTSSHITIDSRYASLIPNSLDYIEASSITSSYILSLYGIFDIGNLDIQDNESILIHSGTGGIGLSALNSLRWKGHKSHLFVTVSSKEKEQYLRDNYGSFITGIYSNKDKNYPKLIKEKLNQLGSNKQGVDLILSSLPNGDDNLNFKCLAKNGRIIDLSNNIDLFNISKSKIKKLLNTINDGFESGELQVIPIIEFSNSNIRDAIEFINERQHIGKIVISHDDSNLLIDLINKHSNQPNYSILKSDYQISQSNLGKNILITGQSGIVLEILKWIIKFSNSIENVIILSKSLMKWELELLIGKTMKKANNKIKFHFKSVDVSDSIQVENSINQILNDNPNIVNIDSIFHFAFTQITKKVEEIDMESLNVSHNAKTIGAINLHNQSINRNWRLNNFVMASSATSIIGSTDQCSYVCANTVLDSLSKYRKSIGLPSICTNYGAIESAGFVSKNESVAAMFNGIGIISISTDLILGTLDLQIQNQQSSTNLMLSDFNFLNFVNNNLQLSLISKFDFQTNLAKNQVNEKLQNQTQNQNLQIQSPSSTTDCQTIIKDSFLHKISEVLSIDISKLNLDLKLLDYGADSLAIVQIKNWIDMEVSPNLIVIQQLQTFTITSSIQYTINSFLKKKVQSQE", "length": 2551 }, "evidence": [ { "id": "G3MZM9", "url": "https://omabrowser.org/oma/group/G3MZM9/", "database": "OMA" } ], "glygen_name": "Cellular slime mold", "common_name": "Social amoeba" }, { "uniprot_canonical_ac": "Q559I8-1", "protein_name": "Uncharacterized protein DDB_G0272530", "gene_name": "", "tax_id": 44689, "organism": "Dictyostelium discoideum", "sequence": { "sequence": "MKIKLILVLIVFLTIVNVNNSIDLCLSNPKKALVNQACKYSTDCEYPLFCGSGNGYGKNATCSKNIETGGSCESNNQCTPCNVCFNAKCKVKLYLGDACDENKSYCSSSVCIKGKCSIQGDVCTANNQCKFNNYCKSGKCVPLEKEGSSCDKDSSCSLTNACVGGKCVTKYQKPLGAVCNSSNECQVFSGHVCGANGKCSVYNQLLSKCKENSDCGPNGMCMCKSETENVCVDLSVGALKNDKCPSLLSSFSSCMTRERCTENTPTGCPKCYPIFMCYQYSCFYMNQFIRSTQNYYKSFCS", "length": 301 }, "evidence": [ { "id": "G3MZM9", "url": "https://omabrowser.org/oma/group/G3MZM9/", "database": "OMA" } ], "glygen_name": "Cellular slime mold", "common_name": "Social amoeba" }, { "uniprot_canonical_ac": "Q559Z2-1", "protein_name": "E2F/DP family winged-helix DNA-binding domain-containing protein", "gene_name": "", "tax_id": 44689, "organism": "Dictyostelium discoideum", "sequence": { "sequence": "MNISLLLNNRNRNRNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNSNNGNANESASLNNGSEEIRSNPSSNFSSPIQSSLSSSSSSLSSNQATTPKKRSHAHKNSLKCQSPQMSPQMSPQMSPQMSPPLQYFPQHQMQHLSQYQLDHLQQQQQLIQQEQQEKQQQQQQHQHQQQQQEQQKQQQKQQQRLSPQPRSSQPRSSPPRSSPQRSPQLNQQEGHINSVQTYSGNNINDKNQNNTNNNNNNMSNNNNFHDDNNCNVNYNNIRNNSNNNNNNNTNNNNNNNNNNNNNNNNNNNNINNNNNNNNNSNNNNWNNNYCNNSFADETNKNNTYGMEYINISEENQYNNNNNNNNSNNNNNYNNYNNYNNNNNNNNNNNNSNNSNSNNNNNNNNNNNNNNNNNRNNIINSNINNSNNNNYNDNGYNNNSNINSNDSYNNNNNNNNNFNNNNFNNNNNNNNNNNNNNNNNNNNNKNNNNSNSYNNNNNNYNNNNNNFHNNNNNSAHNNNNNNYNNNNNNNYYNSNNNNNFHNNNNNNNNNGNNFNNNNNNNGNNGNMFTNVNSIDNVNRNNYNNYNGNNNYNGNNSNNNNNSNNEVSQITTTSLPVKKTKVFKAPREKKFKRGPDQDIREIKPATALLKQYFIGNSITEFNAERVGSILKINHEKLKDILDIMECASLVINNHSNNYVWLGLDNPGFLKLVFNVFHCSSNLVTKEPEFACLKCKENAYRCPTSVDLPKDTRLGSTVCQFMKLLLSKRIRTNPVNDFLTIYQVCFNFNFCSEGRCPEEDFKYLRNTAKVKRCYDVANVFNGLNILEKVGKSKIHSYQWCGDFTIQDCENGCPFGHPLLTPGTAYTTNPSPNPFNQFSNAYISSSAQSSLSNSPFIQGGFHGNNNNSNNNNINGNNINGNNNYGYNNNNNYNNYNSNNSNGFNNGNSFFQQQQPLVNSGVSMVRNNNYSYSP", "length": 964 }, "evidence": [ { "id": "G3MZM9", "url": "https://omabrowser.org/oma/group/G3MZM9/", "database": "OMA" } ], "glygen_name": "Cellular slime mold", "common_name": "Social amoeba" }, { "uniprot_canonical_ac": "Q55A39-1", "protein_name": "Transcription initiation factor TFIID subunit", "gene_name": "taf9", "tax_id": 44689, "organism": "Dictyostelium discoideum", "sequence": { "sequence": "MSSNETLPNSEQENNSKTDTKNDNKNIGDENKIIDTDKDMKDNDTINGKENGNININSNNNNNNNIDTDKEMKETSSIEEDDNNNNKNQNNNNNNNIKEENDNLTELKNNNNKENKENKEETIKEDKEKENNKEPVKNKEETNNINNNNNKNNNSDNINNNNNNNSKETLNKISSMSKVSLTSESSEINGQVNTGVVNNNTNIDITQTNLDEPRDSRVIKSILKTMGIQAHEPRVVNQLLEFMYKYVFEVLQDAMIYGEHSGKTDIDVSDVRLSIQSRVNYQISTPPPRELLLSIAEEKNKTPLPPIPNRYGVFLPPDEYCLTNPNYQANPTKPVFQPVQPLVGNTSRGNYNKKQSDKQVSIKFNSMSNNSTTTTTTTPPTIGSQNGTTIVSPPNLGSLGTTTTTTTTTITPPPPILPLSSNIKPPTLSIPSSITSPPTVTTKNTSTPIIGLGSTTVAPPKTSSSSSTIAPPVLSLPTSITSPPTVTASSTTTTTTAPTTTSPTIPSLSSPTTAATTITVKKEDVKMDDFDDFDGQMKDDITPSSTPQQPSQPTESETTTTATATTTPAVTTTTIPPTTTSTTPPTTATTSTTPPPSTTTTSTPPTTSTTPPPQIKEEK", "length": 619 }, "evidence": [ { "id": "G3MZM9", "url": "https://omabrowser.org/oma/group/G3MZM9/", "database": "OMA" } ], "glygen_name": "Cellular slime mold", "common_name": "Social amoeba" }, { "uniprot_canonical_ac": "Q55B17-1", "protein_name": "Amine oxidase domain-containing protein", "gene_name": "", "tax_id": 44689, "organism": "Dictyostelium discoideum", "sequence": { "sequence": "MYKKILLIFALFILVNINFASSEFKKNETESANLKSLYASYLMKNNNNTKYNNNDNSNNTNIYNDSVTKNKSKNKNELTVGIIGGGIAGLYAGMLFIKSMIFDDLGIDYTILEANKERVGGRVYTHKFDDHKYSYTDLGAMRIPLTPLMDRIVSNQNYSLFSKLAKGGYQIPTVPFLISVNNEISYYNGIRVLKGSPVLNPSDPFNYSDSNNGGPGKGIPDEYANRTVDSLILPVFYQFINNLTVDFYNGFKQMLKYDSYSARDYLKTFHNYPNSVIEYIENLSTISGRLDQTSITELLMSVFDFSGEKFVCVEGGTGLIVKSMSQIIKKKVEMGSFVTKISKSFDKKNNEIDGLNVEVVRDSNFGGSDTEILKFKHVISTTTLPALQRIDTSDLKLPLKLKVAIRSLKYTGAIKLAINFKYRWWEDSEFMSGKPIRGGSSNTDLLLRQVVYPSYGINNGTKGVSGVLLASYSGGLESIRISSMIGKKDKERKLLNIVLRDLAEIHNVDLKKLKNLYKDHFFQSWDNDEFSSGAFALFSTSQYTELFPSTGQSHVDGRFHLSGELTSVHHAWMIGGLNSAYRSVDLILKNEGFEDLRIKLRNNWGTIEQAEYPSLDWYKYDSDINHYKLY", "length": 630 }, "evidence": [ { "id": "G3MZM9", "url": "https://omabrowser.org/oma/group/G3MZM9/", "database": "OMA" } ], "glygen_name": "Cellular slime mold", "common_name": "Social amoeba" }, { "uniprot_canonical_ac": "Q55BT6-1", "protein_name": "Uncharacterized protein", "gene_name": "", "tax_id": 44689, "organism": "Dictyostelium discoideum", "sequence": { "sequence": "MKLLYIVVFLLFAIKLCCSEYCGETYCVENRNCYSFIGCRNSTCLYETIDLDDEVDCTVDTCSDRYGVKNTPNNSLCPPENLCDMFLCDTQSGCVAIPKVNCPAPNPCQIPLGCNRETGICEYDEIDCHDDNECTNDYCDPILGECVHFSNDTICSNKASNFSTCVLSGVCGEFGCKYVEDNCNDGNPCTDDYCDFKNGCVSQKNDWNCDSLSACSEGICTDNGCVQQEVDCDDDNPCSEDFCHPLFGCGSILNDTICTNGNKCVNSTCTEDGCSLPVPIVCQDGNPCSDDTCNPSTGCQFTLNNSNCNDGKKCTIDQCGLNGCTHTNITCPPKRVVDIILIGLICRNHYCDQSTGNCVPDMNSVSLLCI", "length": 370 }, "evidence": [ { "id": "G3MZM9", "url": "https://omabrowser.org/oma/group/G3MZM9/", "database": "OMA" } ], "glygen_name": "Cellular slime mold", "common_name": "Social amoeba" }, { "uniprot_canonical_ac": "Q55C69-1", "protein_name": "Chromo domain-containing protein", "gene_name": "hcpC", "tax_id": 44689, "organism": "Dictyostelium discoideum", "sequence": { "sequence": "MGKTNKKKIEEESEEEEAGDVFEVEKILDKRVQHGRIQYNIRWKGFSADYDTWEDEANVVGCPELVREFESSRIKEKKKNRKRKNVIIDEDPTEEISSSLSSILSSPQPQPPPPLQLTNHSPASSELAITTNTFLISNCTSTSNKTKISIENEEIIKNDHARYGVPYVEGIGFENGDCVDEIVGCKPFGENNLLYFFIRWRGKEKLSWVSNESIKQKEPLQLIEFYESRLKFGYKGEEN", "length": 239 }, "evidence": [ { "id": "G3MZM9", "url": "https://omabrowser.org/oma/group/G3MZM9/", "database": "OMA" } ], "glygen_name": "Cellular slime mold", "common_name": "Social amoeba" }, { "uniprot_canonical_ac": "Q55CH5-1", "protein_name": "Reverse transcriptase domain-containing protein", "gene_name": "", "tax_id": 44689, "organism": "Dictyostelium discoideum", "sequence": { "sequence": "MIAKTQIKCTTIYAPAKSNERHEWYKENLTEEILHSDIITGDFNVDCSVDNNLNKYIKTIFDEFEFTEIKNGITFPRNKSTIDRVFVSKKILHLNPIVTTKEIKLKSDHNMVIIELKIPEYEQQKKGERLWRQNLETLKMNSTSLKINKTIKYYNKKFEENTSKWYKLNICEQWLKLKDEIKKLSINIEIRESNKTKNKLKELAEKLETAKDSRAIFLKEEINNILKEQVRIKQANQTNTHINNKETPSKYLTRRLKVQRKTNEIPQILDPSNNCLVTKHEDILEVARRYYENLYQKRECNEDTHHELLKTFNKRIDQKILDEINQPIEGYEIRLGIEKIQEGKAPGKDGLLPTFYKNHINEILPIISKLYNHFWNTTIPKDFKQGILITIYKNKGDPNNLDNYRPITLLNVDYKIYSKIINNRILKFLNKIISPFQTGFVPRRLLHDNIITLNSTIEIIKREINTKEDMEPIITFYDFEKAFDSISHNAILRTLAHLKLPLKMVLTIMNLLNESETSVYINNSLSKSFTSKRGTKQGDPISPTIFALVVECMATTIINDRCINGVTKETIKILQFADDTATIAYNFMDHFLMNEWIKKFCQATSAKINQTKCSCITFKWNTRTLYTVIKSNERYLGFDFNNKGIKSKINTISDNIRAKLVTWNSTSSTYMGRLIMAKTYALSQLTFHTYINTTPQHNSIENNIVKFVFNTKSKNSLSLQRRQNNYINGGLNLWNLKTRELAQKAWLFERYLHQRVSNTPSSYIKLWEEELKNNNNNKTTTKQNQLQLHWQCKQAWTQLKTPQNKQTHYEHLPKLKKIYEDMMTTQSPEHNKFIPTPGQKEIMTKINSKHLPFKEIKKIINMKGRDLLWRYTLKALPKIYNMPCQQCGEDETSEHIFFNCKAHIKNTQEIFNYTLTKCGHTTHTWNVKILNHLQIALVANLIAIIFDKIWHKRNKLIHDEKEIIIHRQQVIRELIKTQRAAWDRTQAVINKTLRIKSKQRPEEQNKLDSLISLKLLQFSRQWNSPLHAIELPKHLKKNNNSLSTFYK", "length": 1047 }, "evidence": [ { "id": "G3MZM9", "url": "https://omabrowser.org/oma/group/G3MZM9/", "database": "OMA" } ], "glygen_name": "Cellular slime mold", "common_name": "Social amoeba" }, { "uniprot_canonical_ac": "Q55CH7-1", "protein_name": "SsDNA-binding transcriptional regulator", "gene_name": "", "tax_id": 44689, "organism": "Dictyostelium discoideum", "sequence": { "sequence": "MIFKITRTKRRWTKNQKKILVMKVVEKKVVVKKSKTPNTSPSSSSSSSSSSSSSSSSSSTNDKSFNLSDKRKISYSNFKGLERIDIREFFEDKSGELKPSSKGISLTREQLVVILENGDTIKDWIKESK", "length": 129 }, "evidence": [ { "id": "G3MZM9", "url": "https://omabrowser.org/oma/group/G3MZM9/", "database": "OMA" } ], "glygen_name": "Cellular slime mold", "common_name": "Social amoeba" }, { "uniprot_canonical_ac": "Q55CJ7-1", "protein_name": "diaminopimelate epimerase", "gene_name": "", "tax_id": 44689, "organism": "Dictyostelium discoideum", "sequence": { "sequence": "MEPSIDNKPSFRINFTKMHGAGNDFVVFEKNKVERLNGDKSTVTFEEIVGFTTKIAHRKLGIGFDQLIVIDDNPIDKNAAYGMDVINCDGNIEVMCGNGVRCFSKYIVDNKVLSKNLKEQLNFDGDDDIEQIIETKSGIVKTYPLLKHHLNNKDNDVIMVKVNMGTPKVSRFINEIDRHIPKVLTNQSPIESYMYTIDIGLPYCSKLECVYVTVGGNQCVVFIDRNIELGYLDSSYGDHTKFSTIDFKEISDIIQSNVNGFDDIPNVEFVIQSPQDKLENKVISRVVERGNGETLACGTGACGVAISSILKGYCNENTEITVEMPGGKLLIQWNPNNEIFKTGPATSVFKSQILI", "length": 355 }, "evidence": [ { "id": "G3MZM9", "url": "https://omabrowser.org/oma/group/G3MZM9/", "database": "OMA" } ], "glygen_name": "Cellular slime mold", "common_name": "Social amoeba" }, { "uniprot_canonical_ac": "Q55CV8-1", "protein_name": "Lipocalin/cytosolic fatty-acid binding domain-containing protein", "gene_name": "", "tax_id": 44689, "organism": "Dictyostelium discoideum", "sequence": { "sequence": "MELLVGGTILGALTYAYSSLKRTIPEGAHACSPFYPEKYVGKWYEIARLDFYYERDMNNVSAEYTLNKDGTISVINSGYNYVEKKRESVNGKALFVHGSDEAMLKVSFFGPFYAGYNVIAIDPDYKYALVAGRSLDYLWILSRETSIPDHIKKQYLELAESIGYNTSKLIWTEHDNINNKKD", "length": 182 }, "evidence": [ { "id": "G3MZM9", "url": "https://omabrowser.org/oma/group/G3MZM9/", "database": "OMA" } ], "glygen_name": "Cellular slime mold", "common_name": "Social amoeba" }, { "uniprot_canonical_ac": "Q55D49-1", "protein_name": "Reverse transcriptase domain-containing protein", "gene_name": "", "tax_id": 44689, "organism": "Dictyostelium discoideum", "sequence": { "sequence": "MIKIMTWNCQGCSTIKSMNQTKNTINLIKPDISILTETNLKKDQNLAQIKNHYSTGGKGKEARGKGVMAINHLEQIEIKNLEEKEGRILKFTAILNNMEINIICIYAPASYDRRKGWFSNNISLEDLEQADIVTGDFNINKYAKIKFKDGSSDKRKFTENETIEFLMMEVGLTEILPNSTTKTTFKDKLIDRTFLSTKMHQLNHSYKIIDKINKSDHNIVVMDFKIPNFTKIYKSPLWKMNSIIIKEDKTIKKIEKIIDHYQETKRKNINITEYWIKFKKKIKKQCITTEKKRILERKKTLSNLANEHTKTKNKYEKETISNEITILQEEERIDRMIKSSINYINNKEIASNLLTSILKKRDSSSQIHRIKNPSNGEIETEQKEITDCFRKYYETLFKEKECDQETHTELLSTWNPPIDKKKLTEMEDRIEEYEVKLAIEKIAEGKSPGEDGITSSFYKIHQHKLIPILTELFNFFLNNEIPTEFKNGILTSIYKGKGDVLEISNRRPITLLNVDYKIYSKIINNRILKILPNIISKYQNGFIPGRLLHNNIIALDLAMEKSDRNTIITFYDFEKAFDSISHKALIRTLNHLKFPRKITNTILSMLTNTNIRVMVNGQLSESFRAGRGTKQGDPISPTLFAIVCECLSTSIRKDNTIIGIKLNQNNSMKIGQYADDTVTLASNIDDADKMDMKVIKFCQATAAKINDNKCVCITKNPKIKTKYKTIGAKEEERYLGFFFNRKGVISKVDDTVNKLENLTKCYSSVSSTLKGRITILKSYLLSQLTFQLYINEINDIKKLENVNANMLFKGDRWAISKERSRRDYEIGGLELWNMATRSNAQKAWIYEQYLREKDDQNCPPHMEVWKSEKENSLSRIHIKCWKAWKLLHHPRERITLKLNQVKPKYENKQKLKVIYRNMMDIKYKGWNKHQPTTGQKLIQKNINHPILPFREARSITTIKGRDLAWRYLLKALPKHHGENCHSCKEEESSMHIFFECKSIKQNIDSIYQKVCKDSNNTYHGPWSEKVLGKLLTPFSSNLIGAIMESIWYRRNQIKFNDNTTIITENQIIHKIKKARDAEWDRTRKIVEKQLRQELRCTDNRESINRTASIKRRLEKFSHNWNSKLMTINIPEHFIPYCSYNTNYS", "length": 1144 }, "evidence": [ { "id": "G3MZM9", "url": "https://omabrowser.org/oma/group/G3MZM9/", "database": "OMA" } ], "glygen_name": "Cellular slime mold", "common_name": "Social amoeba" }, { "uniprot_canonical_ac": "Q55D57-1", "protein_name": "J domain-containing protein", "gene_name": "", "tax_id": 44689, "organism": "Dictyostelium discoideum", "sequence": { "sequence": "MIQVKNKIKIISILITLFILTINQVVECKSSLYYSILNDYEKGIDYYKILNVTKDSTYSEIKKSFRKLSLKHHPDRNVEKSSHSLYILLNQAHSVLTTDETRKEYDELLVNGIPWHENYYGKYAYRYTGISHDLRHVLLGLIIVITIGKFVYQYNKHHSMIKRAKQTDQYKKRLAQLDGDEDEIQLVIQGADKPTISSLFIIQLFFIFPFKILKSIYTFIFINKFKFIQKTDEEKEEEYRLKMGYTKEDWEYHKKKSIERMEKLKQSGKYKKYLRSKNK", "length": 279 }, "evidence": [ { "id": "G3MZM9", "url": "https://omabrowser.org/oma/group/G3MZM9/", "database": "OMA" } ], "glygen_name": "Cellular slime mold", "common_name": "Social amoeba" }, { "uniprot_canonical_ac": "Q55E25-1", "protein_name": "DRBM domain-containing protein", "gene_name": "", "tax_id": 44689, "organism": "Dictyostelium discoideum", "sequence": { "sequence": "MSNKSHTSEKVQLNEFLQKKKQPIPIYHTESKGSEHNKDFKSIVVVNGKQIESDWKKSKKESEKDCAKNILEFIETLDGYPIYFTPFSKDPPQNNKKIYDEKLQAVYNSVSSGIEGLNNNSFFTKIENNNNNSSSNNNNNLDHNHSNDSSHTSTDNNDNNSNNHNNNNNNQINIDLTMENVNISQSKTITNEGTLNNDNDNNNNSIQQQQHQPQPQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQCFDKDKTNLKKKKKIPFSYNTDLIEHIDLFKRQDFPQTYPSRTTYTDTGHTQQLQKQVFLLTEKIGLMELFYKKQIRVILKSHHNLETELSALKSFVEDCSVTPIEGLELYSIPVPLNPNAKPSAGTTPVLSKSETQNEIIQPTKPPTKPPASCLIKKKIPNVNMKATNKTTTTTSTSTSNSSTTIKTTDSFKNTTNNQHPNTLKPMVSKINQQTSDFIFPLPKPIIRRNPIGNGNLEKKIEKKNSKPNTIVLGVDTQSQSKTKITPSPTTPPPETTPTTPTTTATPTTPTTPTTPTTTATPPPTTTATPPPTTTATPPPTATTPPPTTATTTPPPPPIIATTKTTATATATTIPIDLNEIQIPIRSPQDLTVNQSMISTAMMIASAAQRNPKLTMKLKRKLEESPTLMSKLQKIQFEKEEEILCSQDLHSPIMSPQSPTHQPKTLEPLSPTKKSTQKSPPPTSPSPIVTRARASSNLLPIQNLISKK", "length": 733 }, "evidence": [ { "id": "G3MZM9", "url": "https://omabrowser.org/oma/group/G3MZM9/", "database": "OMA" } ], "glygen_name": "Cellular slime mold", "common_name": "Social amoeba" }, { "uniprot_canonical_ac": "Q55E47-1", "protein_name": "Reverse transcriptase domain-containing protein", "gene_name": "", "tax_id": 44689, "organism": "Dictyostelium discoideum", "sequence": { "sequence": "MIAKTQIKCTTIYAPAKSNERHEWYKENLTEEILHSDIITGDFNVDCSVDNNLNKYIKTIFDEFEFTEIKNGITFPRNKSTIDRVFVSKKILHLNPIVTTKEIKLKSDHNMVIIELKIPEYEQQKKGERLWRQNLETLKMNSTSLKINKTIKYYNKKFEENTSKWYKLNICEQWLKLKDEIKKLSINIEIRESNKTKNKLKELAEKLETAKDSRAIFLKEEINNILKEQVRIKQANQTNTHINNKETPSKYLTRRLKVQRKTNEIPQILDPSNNCLVTKNEDILEVARRYYENLYQKRECNEDTHHELLKTFNKRIDQKILDEINQPIEEYEIRLGIEKIQEGKAPGKDGLLPTFYKNHINEILPIISKLYNHFWNTTIPKDFKQGILITIYKNKGDPNNLDNYRPITLLNVDYKIYSKIINNRILKFLNKIISPFQTGFVPRRLLHDNIITLNSTIEIIKREINTKEDMEPIITFYDFEKAFDSISHNAILRTLAHLKLPLKMVLTIMNLLNESETSVYINNSLSKSFTSKRGTKQGDPISPTIFALVVECMATTIINDRCINGVTKETIKILQFADDTATIAYNFMDHFLMNEWIKKFCQATSAKINQTKCSCITFKWNTRTLYTVIKSNERYLGFDFNNKGIKSKINTISDNIRAKLVTWNSTSSTYMGRLIMAKTYALSQLTFHTYINTTPQHNSIENNIVKFVFNTKSKNSLSLQRRQNNYINGGLNLWNLKTRELAQKAWLFERYLHQRVSNTPSSYIKLWEEELKNNNNNKTTTKQNQLQLHWQCKQAWTQLKTPQNKQTHYEHLPKLKKIYEDMMTTQSPEHNKFIPTPGQKEIMTKINSKHLPFKEIKKIINMKGRDLLWRYTLKALPKIYNMPCQQCGEDETSEHIFFNCKAHIKNTQEIFNYTLTKSGHTTHTWNVKILNHLQIALVANLIAIIFDKIWHKRNKLIHDEKEIIIHRQQVIRELIKTQRAAWDRTQAVINKTLRIKSKQRPEEQNKLDSLISLKLLQFSRQWNSPLHAIELPKHLKKYNNSLSTFYK", "length": 1047 }, "evidence": [ { "id": "G3MZM9", "url": "https://omabrowser.org/oma/group/G3MZM9/", "database": "OMA" } ], "glygen_name": "Cellular slime mold", "common_name": "Social amoeba" }, { "uniprot_canonical_ac": "Q55E48-1", "protein_name": "thioredoxin-dependent peroxiredoxin", "gene_name": "", "tax_id": 44689, "organism": "Dictyostelium discoideum", "sequence": { "sequence": "MTKLKVGNIAPDFEAKNYLGQIVTLKEFKEKSQPIVLYFYPKDNSPECQKSCEFRDKYQKSIEAGAEVIGVSSDGEDSHKSFVSKYSLPFTLLTDKHSKLAKLYGVNGILLPGRKTFIIDKHGFMAVFMMVYSVQLLMSMNL", "length": 142 }, "evidence": [ { "id": "G3MZM9", "url": "https://omabrowser.org/oma/group/G3MZM9/", "database": "OMA" } ], "glygen_name": "Cellular slime mold", "common_name": "Social amoeba" }, { "uniprot_canonical_ac": "Q55ED8-1", "protein_name": "Decapping nuclease", "gene_name": "", "tax_id": 44689, "organism": "Dictyostelium discoideum", "sequence": { "sequence": "MKQTLNVIGLINFIKKQRSFNKSPITITKPLEITRFSYEGNQLFPAKLKKFKNPTIDSDLLVGFQGPDSIESDSQTPLSLVLNKLIETKHDVSKSNFISFRNSFRKLFESMYDSEKWNIQVQRINSTIHLGMDNPTQDFHQLKNFHLKSMYSGNYFEKISTIDNNNNPNDNKHKYCSIIQSKLFNNNFILACEIDCWKKSIQNNNNNQNNNNNENNNNDDDDENYNIDDYVELKTSRDIEDSKANYQFRSKKLIRIWFQAYIAGVSKIFLGIRNDDFFLKKCLNFNTHDLPNQAINWNKDEMLIYGNEILEFIKNNTCSGKSYTLSFNYPIISLVESDSINIINDQYLQYYLNIPKNFENNYNQNNNQNNNNNNNNENNSDDTKNNNIQNNNENNNIQNNNENNNQNNNEKNQKRNFGEEKEIKGDENEERLSKKQKKLE", "length": 440 }, "evidence": [ { "id": "G3MZM9", "url": "https://omabrowser.org/oma/group/G3MZM9/", "database": "OMA" } ], "glygen_name": "Cellular slime mold", "common_name": "Social amoeba" }, { "uniprot_canonical_ac": "Q55EZ2-1", "protein_name": "Reverse transcriptase domain-containing protein", "gene_name": "", "tax_id": 44689, "organism": "Dictyostelium discoideum", "sequence": { "sequence": "MIAKTQIKCTTIYAPAKSNERHEWYKENLTEEILHSDIITGDFNVDCSVDNNLNKYIKTIFDEFEFTEIKNGITFPRNKSTIDRVFVSKKILHLNPIVTTKEIKLKSDHNMVIIELKIPEYEQQKKGERLWRQNLETLKMNSTSLKINKTIKYYNKKFEENTSKWYKLNICEQWLKLKDEIKKLSINIEIRESNKTKNKLKELAEKLETAKDSRAIFLKEEINNILKEQVRIKQANQTNTHINNKETPSKYLTRRLKVQRKTNEIPQILDPSNNCLVTKNEDILEVARRYYENLYQKRECNEDTHHELLKTFNKRIDQKILDEINQPIEEYEIRLGIEKIQEGKAPGKDGLLPTFYKNHINEILPIISKLYNHFWNTTIPKDFKQGILITIYKNKGDPNNLDNYRPITLLNVDYKIYSKIINNRILKFLNKIISPFQTGFVPRRLLHDNIITLNSTIEIIKREINTKEDMEPIITFYDFEKAFDSISHNAILRTLAHLKLPLKMVLTIMNLLNESETSVYINNSLSKSFTSKRGTKQGDPISPTIFALVVECMATTIINDRCINGVTKETIKILQFADDTATIAYNFMDHFLMNEWIKKFCQATSAKINQTKCSCITFKWNTRTLYTVIKSNERYLGFDFNNKGIKSKINTISDNIRAKLVTWNSTSSTYMGRLIMAKTYALSQLTFHTYINTTPQHNSIENNIVKFVFNTKSKNSLSLQRRQNNYINGGLNLWNLKTRELAQKAWLFERYLHQRVSNTPSSYIKLWEEELKNNNNNKTTTKQNQLQLHWQCKQAWTQLKTPQNKQTHYEHLPKLKKIYEDMMTTQSPEHNKFIPTPGQKEIMTKINSKHLPFKEIKKIINMKGRDLLWRYTLKALPKIYNMPCQQCGEDETSEHIFFNCKAHIKNTQEIFNYTLTKCGHTTHTWNVKILNHLQIALVANLIAIIFDKIWHKRNKLIHDEKEIIIHRQQVIRELIKTQRAAWDRTQAVINKTLRIKSKQRPEEQNKLDSLISLKLLQFSRQWNSPLHAIELPKHLKKYNNSLSTFYK", "length": 1047 }, "evidence": [ { "id": "G3MZM9", "url": "https://omabrowser.org/oma/group/G3MZM9/", "database": "OMA" } ], "glygen_name": "Cellular slime mold", "common_name": "Social amoeba" }, { "uniprot_canonical_ac": "Q55F94-1", "protein_name": "Dynamin-like protein A", "gene_name": "dlpA", "tax_id": 44689, "organism": "Dictyostelium discoideum", "sequence": { "sequence": "MSVFKKKDKSDDKKKKHDEETPQGTFQPASQSTSNTNLNSLASSVNNGASVGSTNGSTPNNSNGSTPTYNHNNSAEELEKQKKEEDEKRKKSELEAAAAVVAKKKEDEEKQRKEQVELERKRRDEEIRRTNAAAANAANKELNEQVEISSLEQMGKLDPSSTIHDMFSFFPNEVYNSYEKLQYFSRDLNTAVSHPEIVFVGPRSSGKSSLIEAFIGRALNIVGGGNIVGVGGSNANGCSKRVLYLQFTNNIDFEVPKVTIKKDNTIKEFDHDIIVSIEQLNENLAKRNQLTNDYIEEPIYVSIESRTTLNLTLIDSPGLLFDQSQAESNKIESIVSSLLRPSHRLIIAVESCSQDWKSMSMGQYLKKIDPELSRSTFVFTKFHHTVRGFSSTRDINKYLSGTVPDIKGFFVTLPNHQVRASYSEANRFQEKIYQAHKRDMHALEQLQYDKRYERTIGVAPLRRYILNIVWKSYQDTIPRILKHLRSKRQTAEATLNELQKQSSSLDSTKLRSIASNYTVTFLQITEKLLSGTSEGNPSANGQTLDEEKSQQGDCGEWVDAYKEAIYIDPEEWNIPYWSSKLYGGQQLERLMAEFKAVCDNSKISEVKMDDIATASGINKLNNIPNYAWAASDLTSLISRDTFVPLIEQLCERAMYIMKRLTDIADKVIDSRRKSRCIGSSPFGGNGLNNINSGGNNGININDRLSNTDMDSLDQYPFFTHHVKNLYYDFVHRAAKGCKEKCMDEFYSSRTIYWELTEHPDSSLPSIRNDHHETKTAVCQLATKLFDSIRQRITKNVLLKLYNFFLVPMQTDLWNEIQAQITCLSNEQLEQLFEVQATREQLKQEEKKQQQILEKYSQIDEQFLKAASLFCRPLSNPTPSA", "length": 880 }, "evidence": [ { "id": "G3MZM9", "url": "https://omabrowser.org/oma/group/G3MZM9/", "database": "OMA" } ], "glygen_name": "Cellular slime mold", "common_name": "Social amoeba" }, { "uniprot_canonical_ac": "Q55FX4-1", "protein_name": "SET domain-containing protein", "gene_name": "", "tax_id": 44689, "organism": "Dictyostelium discoideum", "sequence": { "sequence": "MDINSNHIKKINDFKDKGNKEFNKEKNKDKLNKRAITYFQLGIKYFNDEKHKIEINDQINKLISILYSNLSLMYLKGDEIILSLEASNKSIEFNNQNSKAFYYQSICKSYLCDYKGSMESIDKAISISKQDEKVVQQRNRLIEITNNKVKEDVYFENVLKNQKLENVAYENSIEKGRYLISKRLIKRGEEILRIAPFSFSLNGKYVSKFCGVCYQKKSIDNLLKCKDCDDFAICKECKAPNEPLSKYHPNDLCVLYKLNNEYYKMNNFEIANEDNKERGLTDERRLYINTIYNIFKNKTNNKAVVEVDNAISSSVIDVLNLSKKLLNHTNESQRAYSDSTKMKTDILELIFKSFYGANTLKKDEISNIIRIVDCNSHGYSDVISQKKKASGLYPFSCYTNHSCIPNSDYFIDKHGVMVLYASSDIQESEAITISYIYFLNRVEKRRKDLLNGHNFFCTCDQCSFQSSLTEEVCDKCNEIIPSTIGNSNLVYKEPKSLKETGFNYICPKGHTKSSLVYDIDNDQLYPTIAENYSKCKDLRNFRKINIFKEMLENRDFVKKLTPREFEVTPLAKYIANPKKSNSMLFEELINLVRGSVECGLTKSIEESNYSTYLVYDYYDLYKSLLLESKPQILKLNSIRDIIIKLLTPMVYNQNKPRIDKKLNKHLSNKINLKKNK", "length": 676 }, "evidence": [ { "id": "G3MZM9", "url": "https://omabrowser.org/oma/group/G3MZM9/", "database": "OMA" } ], "glygen_name": "Cellular slime mold", "common_name": "Social amoeba" }, { "uniprot_canonical_ac": "Q55G93-1", "protein_name": "Tubulin-specific chaperone D", "gene_name": "tbcd", "tax_id": 44689, "organism": "Dictyostelium discoideum", "sequence": { "sequence": "MENSEDISLNSSEKSIESSVVNLEDQQQSQQQTQQQTCQKTFVQEAPELTILIDKLIQLKHSNKDELISNTTRIIYIIDQYLEQPTLLDIHLNDIIQPLINFIKSNYINNSNNNNTTTTTTTIMTETEIVIKKLSIKNSFRIIYVLSKVRGFKTIVKLFQHEAIDLLPVLDQLEISYHQWVNINKQRDRLNEISVSYSSGINLKNYIKPEEESEQEVVDENNNNINNNHNIDDEYNENIISWEEVYVLALWVSLLVIIPFKFSSLDSASSGTASAAGDGGDGDGDGQLKSISSRILKLGKLALSDVSKIRDSFSELLSKLLNRPDMKFEQKQFIKWCTNSIQLISNNNNNNNQNNSSNNNILLIIGIYSTLATMFKKGNRLDFLPIDMNLYEKIMEANKYLSLSGSERITKKIFLKLLQRIAIIMLPPVSASWRYQKIIKPLLLKGELIKQINNNNNNNNNENNNEEGEEEEEEIPEEIDEILEEIMKSLKDKDTIIRWTSAKAIGRIVNLLPKDMGDQVIGLVIDQMFEKNEFIDADPSAWHGGCLALAELARRGLLLPERLDVVVPLVIRALFFDIIKGTYSIGSHVRDSACYLCWALARTYHNSILSPYLLPICRNLVVVSLYDREINCRKSASAAFQEMVGRHQGLVPNGIEIVTSADFFTVGNKNNSFTSLTTFIGKFQIDYYPIVIKHLATIKIYNWDLEIRQLASKSIHLLTNINPNDIVSNYLPLIIPNTQSDLVHVKHGASLAISEILISLFENNNINLLSDNLKMMILMTIKNTKNEKLFKGKGGVLIRIGMCKIIYSICLVEFSLDKNLSEIKKPTESTSTNGNEDRAAALKLKIAMLKAKTASQINKPIITPPSSKSTTNNNNNNNNNNLNDNEIAFNIILGYLNENLNHPNEEVQKEASKAFELLFSKYISSNEKISLLLELIDSHCKTLKFDINRSARRGSSLLLGSLPFNSANLSYDLLSKVVNELILSIFQDDPKFKDIETRVNSISSLYKIGIYILNLIFKNQENEQKEEEDFKKSKNYNLFIKIWNCLGLATNDYSIDKRGDIGSWVRELSCKVLFDFIKFIITNQNSSTTTTTASTTDLSIENLINEKMITEFICKLFQLSGEKLDKIRDVACKIIHELLWIENPSSINNIPHKEELKKIIVKDQDVHFNWFRTEESLPLICKVLKFNCYLYPLLFGLFSSLGGTSKYLINDSIQSIKQYFSSFDNDEKERFEKIISFSKAILEITNNTTQRMIQPTFRSIYNLLSTHIFDFLIINNLNEQSIFETILFNCYQIIESNQDDIYLLLNSIELFSYFFIQFENNNNEYIKDYSLKALLLLLSNLKYPKVRKLASDQLKKSTRLFINNNGDDETPSLIKSLIFNTKWDDSVDLIIEPLKSLLLLLNQKHLLELLSENPTKKPIPLAPPITSIEELKDKIQNPHKQSDDNNNNNNGELINNNTENNNNNNFDDNLPEDSQDLMEI", "length": 1480 }, "evidence": [ { "id": "G3MZM9", "url": "https://omabrowser.org/oma/group/G3MZM9/", "database": "OMA" } ], "glygen_name": "Cellular slime mold", "common_name": "Social amoeba" }, { "uniprot_canonical_ac": "Q55GP8-1", "protein_name": "Rho GTPase-activating protein gacO", "gene_name": "gacO", "tax_id": 44689, "organism": "Dictyostelium discoideum", "sequence": { "sequence": "MSKLPPPPVQSSPQGFQLPSLHSVQLKPVRPPPQPTQQQLASNTSPREVGTSLSPQSPSNNINPSSSSSSPSSSIRQSPSSSPNVARKVPPTPTNNNGGPPTTTTTTTTTMPPPPAFIKKLSPSSSPILPKRIVSSPPLNGNTAPPPPPIVHLPPPPPTNLPPPPTLSPSSSTTTSPSSSSLNLSGGVPLPPRILRNSDGSANNNNNSNNNSNNNINSLNLSTSGGIPPPPSFFNNNNNNNNNSGSFVNSASSNGSPSLQSQNSVGYFKPPPPPVPTRSASLDPKQMGQFIKPQQNQNNSNNINNINNNNNNIILPPPPNININNNNFVPYIPSNNNQQQSTTPPPIVSISPLKRNSIDNSVVNKRLSQDLNTMLVNRLQHGLSPPVATPFFDDKILGSASKSAELKEKRDQEERERRERERIKKEKEDSEKKEKKEKKGKEEQEKKDKKKKEEQEKKDKKKKEEEEKKSKSSSSSSSSSKKSSSDNTIVNQNIFNNTLSQIMENQRDAQSLSPSSLPYPLILKLLTESIMSLNGPYTEGIFRITGSGTEVNRLKKQINEHDFSLDTQDPHVLAGLLKLWLRELVHPIIPSELYNDAIKSRSKEEVSRIISLIPDQNKEVLNFLIPFLKNVSQPHYAQYSKMDIDNVAMVFSPGLLRSTVLTTDLLLNSQYEKDFVKCLIEMSP", "length": 684 }, "evidence": [ { "id": "G3MZM9", "url": "https://omabrowser.org/oma/group/G3MZM9/", "database": "OMA" } ], "glygen_name": "Cellular slime mold", "common_name": "Social amoeba" }, { "uniprot_canonical_ac": "Q55GR8-1", "protein_name": "Thiamin pyrophosphokinase thiamin-binding domain-containing protein", "gene_name": "", "tax_id": 44689, "organism": "Dictyostelium discoideum", "sequence": { "sequence": "MEKQEEEVQQQQQQQQQQQQPDKNNKETITWDVAEYGGYLFDKKLKAHNPLNHQMPLQYHHSQSTPHIPSSLSTSSTTSIKKPSSSLSDDESGGSSSSTPHSSNTPRKQFSFDDHCALILANQKLPKKLVDYFWDKCSVRICADGGANRLYSLGTKINQSSRWIPDYIKGDLDSLHEGVSDFFSKKGSSIVLDSSQDTSDLQKCFELIIDLEKGSGIKYRKIFILGGLGGSFSHEFANVNTLFDHPGRKIILASKDNLAWLLSSTYNHNIICRSETKCSLIPLSSKASQVTTSGLKWNLVKQSLNFGELISTSNVSLDNKVCVETSNPLIFIVDINP", "length": 337 }, "evidence": [ { "id": "G3MZM9", "url": "https://omabrowser.org/oma/group/G3MZM9/", "database": "OMA" } ], "glygen_name": "Cellular slime mold", "common_name": "Social amoeba" }, { "uniprot_canonical_ac": "Q561S0-1", "protein_name": "NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 10, mitochondrial", "gene_name": "Ndufa10", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MALRLLRLVPASASARGLAAGAQRVGRIHTSVHCKLRYGLLASILGDKTTKKLHEYSRVITVDGNICSGKNKLARDIAEQLGMKHYPEAGIQYSSSTTGDGRPLDIEFSGSCSLEKFYDNPKSNDGNSYRLQSWLYASRLLQYSDALEHLLSTGQGVVLERSIYSDFVFLEAMYNQGFIRKQCVDHYNEIKRLTLPEYLPPHAVIYIDVPVSEIQSRIQKKGDPHEMKVTSAYLQDIEDAYKKTFLPKMSEICEVLVYSSWEAEDSTKVVEDIEYLNYNKGPWLKQDDRTFHNLRMLVQDKREVLNYTTVPVYLPEITIGAHQGSRIYDSFRELPGRKYAPGYNADVGDKWIWLK", "length": 355 }, "evidence": [ { "id": "G3MZM9", "url": "https://omabrowser.org/oma/group/G3MZM9/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "Q568T5-1", "protein_name": "Chondrolectin", "gene_name": "chodl", "tax_id": 7955, "organism": "Danio rerio", "sequence": { "sequence": "MRATLRILCALTFLVSCSRGARVVSGQTVCQGNPEHPCYKIAYFKDVSSRVAFWEALQACEMDGGSLLSIENTAEQKHIEHLLRELSVSSSTGPASITDGDFWIGLTREEGDNAQEPGAFASCPNLYRWTDGSVSLFRNWYADEPSCGGEACVVMYHQPTALAGPGGPYLYQWNDDRCNMKHNFICKYEPESHLVKVQSDRPGGHDVDLSTEDKEDRRTPPTDEDESPRLIIAGPSSMLLIYVIIPTIPLLLLILVASGTCCFQMLSKSKPRTKTSVNQSTLWISKTPKIDSGMEV", "length": 296 }, "evidence": [ { "id": "G3MZM9", "url": "https://omabrowser.org/oma/group/G3MZM9/", "database": "OMA" } ], "glygen_name": "Zebrafish", "common_name": "Zebrafish" }, { "uniprot_canonical_ac": "Q5HYN5-1", "protein_name": "Cancer/testis antigen family 45 member A1", "gene_name": "CT45A1", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MTDKTEKVAVDPETVFKRPRECDSPSYQKRQRMALLARKQGAGDSLIAGSAMSKAKKLMTGHAIPPSQLDSQIDDFTGFSKDRMMQKPGSNAPVGGNVTSSFSGDDLECRETASSPKSQREINADIKRKLVKELRCVGQKYEKIFEMLEGVQGPTAVRKRFFESIIKEAARCMRRDFVKHLKKKLKRMI", "length": 189 }, "evidence": [ { "id": "G3MZM9", "url": "https://omabrowser.org/oma/group/G3MZM9/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "Q5I0J8-1", "protein_name": "PHD finger protein 11-like", "gene_name": "Phf11l", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MAQEEPGGSNSVLNGDANSDKKMEKWTCALCPEGHDWSVIYFEPSSNIAAHENCLLYSSGLVECGPHDPRNPARSFAVKSVKKEIWRGRRLKCSFCNNKGATVGCDLQSCPKNYHLHCAKEDRAILQVDEDYGTYKLFCQRHAPGGQEPTQVDAAVKASFLKKCLEAGLLTELFEQIQQKMISIHGRFMDDTASESDYEGIKILLFDCGLFKDTLIKFEEAIKSKACECEERLNQMKQQLELLADLQQNLRSFQECGVLDPSGSTSGSLLPPEDHQCRCQESPEVQAGSGDSL", "length": 293 }, "evidence": [ { "id": "G3MZM9", "url": "https://omabrowser.org/oma/group/G3MZM9/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "Q5J3E6-1", "protein_name": "Vomeronasal type-1 receptor", "gene_name": "Vom1r12", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MDSKDLAIGVIFILQCSMGILRHFILLSYYLMLHYNKHSLKPIDLILMNMFIANFLIIFPKSMLQTVEAFGIKLLFSVFVCKFLLYIERVGRSVSIATVCLLSVFQAITISPRNSCLYGLKVKVPKYISLSIFLCWALYFVVNMILPVYAYIKWSSNNMTYKRTLKYCFSVGHDEFTGSFFTILFVFPEVFLAILIVWSGSSMVVILYRHKQQVQHIYCNYASTRTSPESRATKSIVVLVSVFICFYSISSILYGCIALFCDNSWSLINIANIISLCFPVLGSFVVSHNPDFPRFSLSWIRNTRRV", "length": 306 }, "evidence": [ { "id": "G3MZM9", "url": "https://omabrowser.org/oma/group/G3MZM9/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "Q5J3E9-1", "protein_name": "Vomeronasal type-1 receptor", "gene_name": "Vom1r15", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MVNDRMESKDLAVGVIFILQCSMGILRHFTLLSYYLMLHYNKHTLKPIDLILMNMFIANFLLIFSKSVLQTVEIFGMELFFNVFVCKFLLYIERVGRSVSVATVCLLSVFQAITISPRNSCLNGLKVKVPKYINLSIFFCWPLYFVINMILPVYGCIKWNSNNMTYKRSVKYCFSIGHDELTSSIFTILFVFPEVFLAILIVLSGSSMVVTLYRHKQQVQHIYCNYACTRTSPESRATKSIVVLVSVFICFYSVSSILYGCIALFCDDSWWLINIAHIISLCFPIFGSFLVSHNPALSRFSLSWIKNTRRV", "length": 311 }, "evidence": [ { "id": "G3MZM9", "url": "https://omabrowser.org/oma/group/G3MZM9/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "Q5J3F0-1", "protein_name": "Vomeronasal type-1 receptor", "gene_name": "LOC100911184", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MDFWNLAIRIIFLSQIIIGILGNVSLLFYYLVLYYREFTLKSTELILMHLMVANIIIIFSAGVPQTMTIWGMKQFLNDFGCKLLLYIHAVGRSVSICTTCLLSVFQAMTIRPQKFCGNDHKVTMERYLGCFISFLWVLYFLVNFIFLVYTYIKKNSNNETRKRDFGYCSTVGSDKISDSLYATLVMCPEVFFSVLIAWSSGSMIVILYRHKQKVKYIYSTHVSRRDYPESRATQNILAQMFTFLAFYTLSSTLRGSIALLSNHSWWLMNINHFTSLCFPSFGPFVLMSHYSIVSRFILFWLRKNCSNFLL", "length": 310 }, "evidence": [ { "id": "G3MZM9", "url": "https://omabrowser.org/oma/group/G3MZM9/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "Q5JQC4-1", "protein_name": "Cancer/testis antigen 47A", "gene_name": "CT47A1", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MSATGDRHPTQGDQEAPVSQEGAQAEAAGAGNQEGGDSGPDSSDVVPAAEVVGVAGPVEGLGEEEGEQAAGLAAVPRGGSAEEDSDIGPATEEEEEEEGNEAANFDLAVVARRYPASGIHFVLLDMVHSLLHRLSHNDHILIENRQLSRLMVGPHAAARNLWGNLPPLLLPQRLGAGAAARAGEGLGLIQEAASVPEPAVPADLAEMAREPAEEAAEEKLSEEATEEPDAEEPATEEPTAQEATAPEEVTKSQPEKWDEEAQDAAGEEEKEQEKEKDAENKVKNSKGT", "length": 288 }, "evidence": [ { "id": "G3MZM9", "url": "https://omabrowser.org/oma/group/G3MZM9/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "Q5QNN9-1", "protein_name": "Trace amine associated receptor 12e", "gene_name": "taar12e", "tax_id": 7955, "organism": "Danio rerio", "sequence": { "sequence": "MMSLNETQTENILLCYPLLSNSCPKLHRLAVVQVGLYVFLLLMILTTVFGNLLIIISISHFKHLQSPTHLIVRSLAACDCLLGLLVMPYSMVRSVEGCWYLGDVVCKVHSSLDMTFCISSLLHLGLISVDRYWAICDPLRYRLRVTNITVTVFIVFIWLFSFVYSFYVVFSGVNTVGLETFIMQVYCVGSCVLYFNKQWGLICPILVFFLPGAIMSSLYMKIFHVARKHAKVMSERVTGGLKSQSSAQRERKAAKILAIVMGVFLFCWLPFFTVNALDPFFNFFTPADIFDAVIWFAYLNSTCNPLIYGFFYPCFQKAFKILIFTYICGVRNLDTFA", "length": 337 }, "evidence": [ { "id": "G3MZM9", "url": "https://omabrowser.org/oma/group/G3MZM9/", "database": "OMA" } ], "glygen_name": "Zebrafish", "common_name": "Zebrafish" }, { "uniprot_canonical_ac": "Q5QNP0-1", "protein_name": "Trace amine associated receptor 12g", "gene_name": "taar12g", "tax_id": 7955, "organism": "Danio rerio", "sequence": { "sequence": "MTSNESENIQLCYPLLSNSCPKLHRLAVVQVGLYICLLLMILTTVFGNLLIIISISHFKHLQSPTHLIVRSLAACDCLLGSLVMPNSMVRSVEGCWYLGDVVCKVHSSLDMTLCISSLLHLGLISVDRYLAICDPLRYRIRVTNTTVTVFTVFIWLFSVVYSFYVKFSGITAVGLEMLILQTYCVGRCVVFFNKQWGLICPVLAFFLPGAIMSSLYMKIFHVARKQAKVISERVTGGLKSQSSAQRERKAAKTLAIVMGVFLFCWMPFFTLTALDPFFNFLSSADVFDALFWFAYLNSACNPLIYGFFYPCFQKAFKILIFTYICGVKKANTLTFE", "length": 336 }, "evidence": [ { "id": "G3MZM9", "url": "https://omabrowser.org/oma/group/G3MZM9/", "database": "OMA" } ], "glygen_name": "Zebrafish", "common_name": "Zebrafish" }, { "uniprot_canonical_ac": "Q5R1F6-1", "protein_name": "T cell receptor alpha variable 5N-4", "gene_name": "Trav5d-4", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MKTYAPTLFMFLWLQLDGMSQGEQVEQLPSILRVQEGSSASINCTYENSASNYFPWYKQEPGENPKLIIDIRSNMERKQTQGLIVLLDKKAKRFSLHITDTQPGDSAMYFCAAS", "length": 114 }, "evidence": [ { "id": "G3MZM9", "url": "https://omabrowser.org/oma/group/G3MZM9/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q5RKI7-1", "protein_name": "Solute carrier family 7 member 13", "gene_name": "Slc7a13", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MAMDIEKKIYLKRQLGYFWGTNFLIINIIGAGIFVSPKGVLQYSSMNVGVSLCVWVFCAVLSMTSTLCAAEIGITFPYTVAHYYFLKRCFGPFVAFLRLWTSLFTGPGVLASQALLLAEYGIQPFYPSCSAPAVPKKCLALAMLWIVGILNSRGVKELSWLQTVSMVLKMGILSFISLSGLFLLVTGRKENVRRLQNAFDAEFPEVSRLIEAIFQGYFAFSGGGSFTYVAGELKEPSKTIPRCIFTALPLVTVVYLLANLSYLTVLSPQELLSSDAVALTWTDRVIPQLTWSVPFAISASLFSNLVTSVFETSRTSYIASRNGQLPLLCSTLNVHSSPFIAVLLDVSMGSIAIVLTNLIELINYLFFVFSIWTVLSVIGILKLRYQEPNLHRPYKVFSPFLFITAAISLSMVLIPLIKSPKMQYIYVFLFFLGGLLFYVPLIHFKLKLIWFQKLTCYLQLLFNICIPDVSDEHVAEEES", "length": 479 }, "evidence": [ { "id": "G3MZM9", "url": "https://omabrowser.org/oma/group/G3MZM9/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "Q5XHX8-1", "protein_name": "Sperm microtubule associated protein 2", "gene_name": "Spmap2", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MGELGEHRSRSSLLSIPVLDTKTSGGSEYRESDGSLDLQSTLFEDHWLQSSQATTERNTDDPEEEIPPEEMVGEELPEVSNLEDSLRRDLEVEVVGMSHLSINERTTPTTSSAKCRKKKNHRLLELAKPKFNWQCLKDRTGRCCKGHVWISPRKTNLQFCLYWPSVYWTERFIEDTTLTITVPEVSRRVEELSRPKRFYQEYYNNNRTTPIWPIPRSTLEYQASNRLKRLATPKIRNNIWSINMSEVSQVSRAAQMAVPTPRTLRLAKPRAPATLLEEWDPMPKPKPYVSDYNRLLQLATPKALSEKCVPDRSPQWEVLNVTKNAVASSRIISLAQPKIRKDLNEGYNPYYISPASLVAQASPRIYELAVPKHITKKV", "length": 378 }, "evidence": [ { "id": "G3MZM9", "url": "https://omabrowser.org/oma/group/G3MZM9/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "Q63550-1", "protein_name": "BPI fold containing family A, member 2F", "gene_name": "Bpifa2f", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MFQLGSLVVLCGLLIGTSGSLFDIFQNPELDVESVWSEINYRIRYALETMDLDMLADYLSKRGIELKIKDLRILNLNHEVSPNGDEVTLKMPMALNASLSLPARDLTTDVSISMEAITSFAIEKDPKTGRRVLNMQRCSLNTDNTSISLLNRKSNFVNLALDSALYLIKRGLTLPVRRQLCPVLQLIISNTFHPDEISNPQTAIST", "length": 206 }, "evidence": [ { "id": "G3MZM9", "url": "https://omabrowser.org/oma/group/G3MZM9/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "Q64583-1", "protein_name": "Cytochrome P450 2B15", "gene_name": "Cyp2b15", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MELGVLLLLTFTVGFLLLLASQNRPKTHGHLPPGPRPLPFLGNLLQMNRRGLLRSFMQLQEKYGDVFTVHLGPRPVVILCGTDTIREALVDQAEAFSGRGTVAVLHPVVQGYGVIFANGERWKILRRFSLVTMRNFGMGKRSVEERIKEEAQCLVEELKKYKGALLNPTSIFQSIAANIICSIVFGERFDYKDHQFLRLLDLIYQTFSLMGSLSSQVFELFSGFLKYFPGVHKQISKNLQEILNYIDHSVEKHRATLDPNTPRDFINTYLLRMEKEKSNHHTEFHHQNLVISVLSLFFTGTETTSTTLRYSFLIMLKYPHVAEKVQKEIDQVIGSHRLPTLDDRTKMPYTDAVIHEIQRFADLIPIGLPHRVTNDTMFLGYLLPKNTEVYPILSSALHDPRYFDHPDTFNPEHFLDVNGTLKKSEAFLPFSTGKRICLGEGIAQNELFIFFTAILQNFSLASPVAPEDIDLSPINSGISKIPSPYQIHFLSRCVG", "length": 495 }, "evidence": [ { "id": "G3MZM9", "url": "https://omabrowser.org/oma/group/G3MZM9/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "Q66X01-1", "protein_name": "NACHT, LRR and PYD domains-containing protein 9C", "gene_name": "Nlrp9c", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MVDSSSYGLLQYFQKLSDEEFQRFKELLQKEQEKFKLKPLSWTKIKNTSKEDLVTQLYTHYPRQVWDMVLNLFLQVNRKDLSTMAQIERRDKQNKYKEFMKNLFQYIWTSETNTYMPDRSYNTIIDRQYKALLDIFDSESDPATAVVLGTRGKGKTVFLRKAMLDWASGVLLQNRFQYVFFFSVFSLNNTTELSLAELISSKLPECSETLDDILSNPKRILFVLDGFDYLKFDLELRTNLCNDWRKRLPTQNVLSSLLQKIMLPECSLLLELGESSCSKIIPLLQNPREIIMSGLSEQSIYFYCVSFFKIQLGVEVFKDLKKNEPLFTLCSNPSMLWMICSSLMWGHYSREEVISSSESTSAIHTIFIMSAFKSIFGLGSSKYKRFKLKTLCTLAVEGMWKQVYVFDSEDLRRNKISESDKTVWLKMKFLQIQGNNIMFYHSTLQWYFATLFYFLKQDKDTYHPVIGSLPQLLGEIYAHKQNQWTHAQTFFFGIATKHVITLLKPCFGNISFKTIRQEIIRYLKSLSQPECNEKLVHPKKLFFCLIENQEERFVSQVMNLFEEITVDISDSDDLGAAEYSLLRASKLKNLHLHIQKKVFSEIHDPEYGSLENFKLDQKFSAINWTMLSILFCNLHVLDLGSCHFNKKVIEVLCNSLSPTPNMPLTVFKLQRLLCSFMTNFGDGSLFCTFLQIPQLKYLNLYGTDLSNDVVEMLCSALKCSTCRVEELLLGKCDISSEACGIMATFLINSKVKHLSLVENPLKNKGVMFLCKMLKDPSCVLESLMLSYCCLTFIACGHLYEALLSNKHLSLLDLGSNFLEDIGVNLLCEALKYPNCTLKELWLPGCYLTSECCEEISAVLTCNKNLKTLKLGNNNIQDTGVKRLCEALCHPKCKVQCLGLDMCELSNDCCEDLALALITCNTLKSLNLDWNALHHSGLVMLCEALNHKKCKLNMLGLDKSSFSEESQTFLQAVEKKNNNLNVLHFPWVEDELKKRGVRLVWNSKN", "length": 1004 }, "evidence": [ { "id": "G3MZM9", "url": "https://omabrowser.org/oma/group/G3MZM9/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q675C0-1", "protein_name": "Taste receptor type 2 member 102", "gene_name": "Tas2r102", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MEPVIYSFATLLIHVEFIFGNLSNGFIVLSNFWDWVIKRKLSTIDKILLTLAISRITLIWEIYTWFTSVYGPSSFAIGMKLQILYFTWILSSHFSLWFATALSIFYLLRIANCSWKIFLYLKWRLKQVIVGMLLASLVFLPGILTQRTLEERPYRYGGNTSEDSMETDFARFTELILFNLTIFSVIPFSLASISFLLLIFSLWKHLRKMQLSSRGHGDPSTKAHTNALRIMVSFLLLYSIYFLSLLLSWIAQKHHSKLVDIIGIITGLMYPSAHSFILILGNSKLMQTSLWILSHLRCRLKGENILNPSGNQVTSCYIFCIANKSVS", "length": 327 }, "evidence": [ { "id": "G3MZM9", "url": "https://omabrowser.org/oma/group/G3MZM9/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "Q68FP3-1", "protein_name": "C-C motif chemokine 6", "gene_name": "Ccl6", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MRHSKTAISFFILVAVLGSQAGLIQDTVKEDRPFNPTIIHQGFQDSSDCCFSYASQIPCSRFIYYFPTSGGCTKPGIIFVTRKRKRVCANPSDQRVQTCISTLKLGPRSGNSAIA", "length": 115 }, "evidence": [ { "id": "G3MZM9", "url": "https://omabrowser.org/oma/group/G3MZM9/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "Q6EKJ0-1", "protein_name": "General transcription factor II-I repeat domain-containing protein 2B", "gene_name": "GTF2IRD2B", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MAQVAVSTLPVEEESSSETRMVVTFLVSALESMCKELAKSKAEVACIAVYETDVFVVGTERGCAFVNARTDFQKDFAKYCVAEGLCEVKPPCPVNGMQVHSGETEILRKAVEDYFCFCYGKALGTTVMVPVPYEKMLRDQSAVVVQGLPEGVAFQHPENYDLATLKWILENKAGISFIINRPFLGPESQLGGPGMVTDAERSIVSPSESCGPINVKTEPMEDSGISLKAEAVSVKKESEDPNYYQYNMQGSHPSSTSNEVIEMELPMEDSTPLVPSEEPNEDPEAEVKIEGNTNSSSVTNSAAGVEDLNIVQVTVPDNEKERLSSIEKIKQLREQVNDLFSRKFGEAIGVDFPVKVPYRKITFNPGCVVIDGMPPGVVFKAPGYLEISSMRRILEAAEFIKFTVIRPLPGLELSNVGKRKIDQEGRVFQEKWERAYFFVEVQNIPTCLICKQSMSVSKEYNLRRHYQTNHSKHYDQYTERMRDEKLHELKKGLRKYLLGSSDTECPEQKQVFANPSPTQKSPVQPVEDLAGNLWEKLREKIRSFVAYSIAIDEITDINNTTQLAIFIRGVDENFDVSEELLDTVPMTGTKSGNEIFLRVEKSLKKFCINWSRLVSVASTGTPAMVDANNGLVTKLKSRVATFCKGAELKSICCIIHPESLCAQKLKMDHVMDVVVKSVNWICSRGLNHSEFTTLLYELDSQYGSLLYYTEIKWLSRGLVLKRFFESLEEIDSFMSSRGKPLPQLSSIDWIRDLAFLVDMTMHLNALNISLQGHSQIVTQMYDLIRAFLAKLCLWETHLTRNNLAHFPTLKLVSRNESDGLNYIPKIAELKTEFQKRLSDFKLYESELTLFSSPFSTKIDSVHEELQMEVIDLQCNTVLKTKYDKVGIPEFYKYLWGSYPKYKHHCAKILSMFGSTYICEQLFSIMKLSKTKYCSQLKDSQWDSVLHIAT", "length": 949 }, "evidence": [ { "id": "G3MZM9", "url": "https://omabrowser.org/oma/group/G3MZM9/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "Q6NXT2-1", "protein_name": "Histone H3.3C", "gene_name": "H3-5", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MARTKQTARKSTGGKAPRKQLATKAARKSTPSTCGVKPHRYRPGTVALREIRRYQKSTELLIRKLPFQRLVREIAQDFNTDLRFQSAAVGALQEASEAYLVGLLEDTNLCAIHAKRVTIMPKDIQLARRIRGERA", "length": 135 }, "evidence": [ { "id": "G3MZM9", "url": "https://omabrowser.org/oma/group/G3MZM9/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "Q6P3W6-1", "protein_name": "NBPF family member NBPF10", "gene_name": "NBPF10", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MVVSAGPWSSEKAEMNILEINETLRPQLAEKKQQFRSLKEKCFLTQLAGFLANRQKKYKYEECKDLIKFMLRNERQFKEEKLAEQLKQAEELRQYKVLVHSQERELTQLREKLREGRDASRSLYEHLQALLTPDEPDKSQGQDLQEQLAEGCRLAQHLVQKLSPENDEDEDEDVQVEEAEKVLESSAPREVQKAEESKVPEDSLEECAITCSNSHGPCDSNQPHKNIKITFEEDEVNSTLVVDRESSHDECQDALNILPVPGPTSSATNVSMVVSAGPLSSEKAEMNILEINEKLRPQLAEKKQQFRNLKEKCFLTQLSGFLANQQKKYKYEECKDLIKFMLRNERQFKEEKLAEQLKQAEELRQYKVLVHAQERELTQLKEKLREGRDASRSLNEHLQALLTPYEPDKSQGQDLQEQLAEGCRLAQHLVQKLSPENDNDDDEDVQVEVAEKVQKSSAPREMQKAEEKEVPEDSLEECAITYSNSHGSYDSNQPHRKTKITFEEDKVDSTLIGSSSHVEWEDAVHIIPENESDDEEEEEKGPVSPRNLQESEEEEVPQESWDEGYSTLSIPPEMLASYQSYSSTFHSLEEQQVCMAVDIGRHRWDQVKKEDQEATGPRLSRELLDEKGPEVLQDSQDRCYSTPSGCLELTDSCQPYRSAFYILEQQRVGLAIDMDEIEKYQEVEEDQDPSCPRLSRELLDEKEPEVLQDSLDRCYSTPSGYLELPDLGQPYSSAVYSLEEQYLGLALDVDRIKKDQEEEEDQGPPCPRLSRELLEVVEPEVLQDSLDRCYSTPSSCLEQPDSCQPYGSSFYALEEKHVGFSLDVGEIEKKGKGKKRRGRRSKKERRRGRKEGEEDQNPPCPRLSRELLDEKGPEVLQDSLDRCYSTPSGCLELTDSCQPYRSAFYVLEQQRVGFAFDMDEIEKYQEVEEDQDPSCPRLSRELLDEKEPEVLQDSLDRCYSTPSGYLELPDLGQPYSSAVYSLEEQYLGLALDVDRIKKDEEEEEDQDPPCPRLSRELLEVVEPEVLQDSLDRCYSTPSSCLEQPDSCQPYGSSFYALEENHVGFSLDVGEIEKKGKGKKRRGRRSKKERRRGRKEGEEDQNPPCPRLSRELLEEKGPEVLQDSLDRCYSTPSGCLELTDSCQPYRSAFYVLEQQRVGFAVDMDEIEKYQEVEEDQDPSCPRLSRELLDEKEPEVLQDSLDRCYSTPSGYLELPDLGQPYSSAVYSLEEQYLGLALDVDRIKKDEEEEEDQDPPCPRLSRELLEVVEPEVLQDSLDRCYSTPSSCLEQPDSCQPYGSSFYALEEKHVGFSLDVGEIEKKGKGKKRRGRRSKKERRRGRKEGEEDQNPPCPRLSRELLEEKGPEVLQDSLDRCYSTPSGCLELTDSCQPYRSAFYVLEQQRVGFAVDMDEIEKYQEVEEDQDPSCPRLSRELLDEKEPEVLQDSLDRCYSTPSGYLELPDLGQPYSSAVYSLEEQYLGLALDVDRIKKDEEEEEDQDPPCPRLSRELLEVVEPEVLQDSLDRCYSTPSSCLEQPDSCQPYGSSFYALEEKHVGFSLDVGEIEKKGKGKKRRGRRSKKERRRGRKEGEEDQNPPCPRLSRELLDEKGPEVLQDSLDRCYSTPSGCLELTDSCQPYRSAFYVLEQQHVGLAVDMDEIEKYQEVEEDQDPSCPRLSRELLDEKEPEVLQDSLDRCYSTPSGYLELPDLGQPYSSAVYSLEEQYLGLALDVDRIKKDQEEEEDQGPPCPRLSRELLEVVEPEVLQDSLDRCYSTPSSCLEQPDSCQPYGSSFYALEEKHVGFSLDVGEIEKKGKGKKRRGRRSKKERRRGRKEGEEDQNPPCPRLSRELLDEKGPEVLQDSLDRCYSTPSGCLELTDSCQPYRSAFYVLEQQHVGLAVDMDEIEKYQEVEEDQDPSCPRLSRELLDEKEPEVLQDSLDRCYSTPSGYLELPDLGQPYSSAVYSLEEQYLGLALDVDRIKKDQEEEEDQGPPCPRLSRELLEVVEPEVLQDSLDRCYSTPSSCLEQPDSCQPYGSSFYALEEKHVGFSLDVGEIEKKGKGKKRRGRRSKKERRRGRKEGEEDQNPPCPRLSRELLDEKGPEVLQDSLDRCYSTPSGCLELTDSCQPYRSAFYVLEQQHVGLAVDMDEIEKYQEVEEDQDPSCPRLSRELLDEKEPEVLQDSLDRCYSTPSGYLELPDLGQPYSSAVYSLEEQYLGLALDVDRIKKDQEEEEDQGPPCPRLSRELLEVVEPEVLQDSLDRCYSTPSSCLEQPDSCQPYGSSFYALEEKHVGFSLDVGEIEKKGKGKKRRGRRSKKERRRGRKEGEEDQNPPCPRLSRELLDEKGPEVLQDSLDRCYSTPSGCLELTDSCQPYRSAFYVLEQQHVGLAVDMDEIEKYQEVEEDQDPSCPRLSRELLDEKEPEVLQDSLDRCYSTPSGYLELPDLGQPYSSAVYSLEEQYLGLALDVDRIKKDQEEEEDQDPPCPRLSRELLEVVEPEVLQDSLDRCYSTPSSCLEQPDSCQPYGSSFYALEEKHVGFSLDVGEIEKKGKGKKRRGRRSKKERRRGRKEGEEDQNPPCPRLSRELLDEKGPEVLQDSLDRCYSTPSGCLELTDSCQPYRSAFYVLEQQHVGLAVDMDEIEKYQEVEEDQDPSCPRLSRELLDEKEPEVLQDSLDRCYSTPSGYLELPDLGQPYSSAVYSLEEQYLGLALDVDRIKKDQEEEEDQGPPCPRLSRELLEVVEPEVLQDSLDRCYSTPSSCLEQPDSCQPYGSSFYALEEKHVGFSLDVGEIEKKGKGKKRRGRRSKKERRRGRKEGEEDQNPPCPRLSRELLDEKGPEVLQDSLDRCYSTPSGCLELTDSCQPYRSAFYVLEQQHVGLAVDMDEIEKYQEVEEDQDPSCPRLSRELLDEKEPEVLQDSLDRCYSTPSGYLELPDLGQPYSSAVYSLEEQYLGLALDVDRIKKDQEEEEDQGPPCPRLSRELLEVVEPEVLQDSLDRCYSTPSSCLEQPDSCQPYGSSFYALEEKHVGFSLDVGEIEKKGKGKKRRGRRSKKERRRGRKEGEEDQNPPCPRLSRELLDEKGPEVLQDSLDRCYSTPSGCLELTDSCQPYRSAFYVLEQQHVGLAVDMDEIEKYQEVEEDQDPSCPRLSRELLDEKEPEVLQDSLDRCYSTPSGYLELPDLGQPYSSAVYSLEEQYLGLALDVDRIKKDEEEEEDQDPPCPRLSRELLEVVEPEVLQDSLDRCYSTPSSCLEQPDSCQPYGSSFYALEEKHVGFSLDVGEIEKKGKGKKRRGRRSKKERRRGRKEGEEDQNPPCPRLSRELLDEKGPEVLQDSLDRCYSTPSGYLELTDSCQPYRSAFYVLEQQHVGLAVDMDEIEKYQEVEEDQDPSCPRLSRELLDEKEPEVLQDSLDRCYSTPSGYLELPDLGQPYSSAVYSLEEQYLGLALDVDRIKKDQEEEEDQGPPCPRLSRELLEVVEPEVLQDSLDRCYSTPSSCLEQPDSCQPYGSSFYALEEKHVGFSLDVGEIEKKGKGKKRRGRRSKKERRRGRKEGEEDQNPPCPRLSRELLDEKGPEVLQDSLDRCYSTPSGCLELCDSCQPYRSAFYVLEQQRVGLAVDMDEIEKYQEVEEDQDPSCPRLSRELLDEKEPEVLQDSLDRCYSTPSGYLELPDLGQPYSSAVYSLEEQYLGLALDVDKIEKKGKGKKRRGRRSKKERRRGRKEGEEDQNPPCPRLNGVLMEVEEREVLQDSLDRCYSTPSMYFELPDSFQHYRSVFYSFEEQHISFALYVDNRFFTLTVTSLHLVFQMGVIFPQ", "length": 3795 }, "evidence": [ { "id": "G3MZM9", "url": "https://omabrowser.org/oma/group/G3MZM9/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "Q6UGQ3-1", "protein_name": "Secretoglobin family 2B member 2", "gene_name": "Scgb2b2", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MKGTLLLLALLVTGELGFQRTEACIPFFGVYLGILSGNRIGLHTELAPFDPTVEEKEAFEKIQDCYEEEGLKAKTEDMKLMTTILFSSECRSYYTKEVLKNILVKFSKKLTHGS", "length": 114 }, "evidence": [ { "id": "G3MZM9", "url": "https://omabrowser.org/oma/group/G3MZM9/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q6YCH2-1", "protein_name": "TD and POZ domain-containing protein 4", "gene_name": "Tdpoz4", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MSGELEAKSRGDTQSHEQKLCYRWTISNFSFFVEETEEYITSLVFSLEDNDKMTWCLRVYPTGVDEKNKDYVSLYLILLSCEKGSVWAKFEVCILNAKGEKCNTERIPSFSRIQPHQPFGFEKFITRDSFLSPAQVLTPDDKFTLLCKVSVLQDSFSISGQNPRPAIKVTRCTLENDVGELWENPLFTDCSLLVAGHEFRAHKAILAARSPVFRAMFEHEMEERLTNCVEIHDLDPQVFKEMMGFIYTGKVPHLHSHSMACDLLAAADRYGLEDLMVMCEDALCRSLSVENAAHTLIVADLHSTEHLKTQALDFIIVYASEVSKTSGWMSMVESHPRLVAEAFHSLASAQRVFWALPFKQLKWSLRPTQL", "length": 370 }, "evidence": [ { "id": "G3MZM9", "url": "https://omabrowser.org/oma/group/G3MZM9/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q6ZMA2-1", "protein_name": "Olfactory receptor", "gene_name": "Or1o1", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MNCTQSPGFILLGLSSDPEKWQLFFSIFLALYLLGFLGNLLLLLAIGADVHLHTPMYFFLSQLSLVDLCFITTTAPKMLEALWTGDGSISFSGCLTQMCLFGVFADMDNLLLAVMAIDRYAAICQPLLYPLLMTPCRCGVLACGSWGIAHCASLVYTLLLSQLSFHSNQEIPHFFCDSRPLLWLSCSDTHLNEFLMMVLSALLGISALLCIVSSYGCIFCAVARVPSAKGRRKALATCSSHLSVVLLFYSTVFATYLKPPSTSHSSGEVVAAVMYTLITPTLNPFIYSLRNKDVKNSLKKLLNMEKPLD", "length": 309 }, "evidence": [ { "id": "G3MZM9", "url": "https://omabrowser.org/oma/group/G3MZM9/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "Q70YC5-1", "protein_name": "Protein ZNF365", "gene_name": "ZNF365", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MQQKAFEESRYPWQESFENVAVCLPLRCPRCGDHTRFRSLSSLRAHLEFSHSYEERTLLTKCSLFPSLKDTDLVTSSELLKPGKLQSSGNVVKQKPSYVNLYSISHEHSKDRKPFEVVAERPVSYVQTYTAMDLHADSLDGTRSGPGLPTSDTKASFEAHVREKFNRMVEAVDRTIEKRIDKLTKELAQKTAELLEVRAAFVQLTQKKQEVQRRERALNRQVDVAVEMIAVLRQRLTESEEELLRKEEEVVTFNHFLEAAAEKEVQGKARLQDFIENLLQRVELAEKQLEYYQSQQASGFVRDLSGHVLTDISSNRKPKCLSRGHPHSVCNHPDLKAHFHPKGRNHLKKAKDDRASMQPAKAIHEQAESSRDLCRPPKKGELLGFGRKGNIRPKMAKKKPTAIVNII", "length": 407 }, "evidence": [ { "id": "G3MZM9", "url": "https://omabrowser.org/oma/group/G3MZM9/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "Q71LE2-1", "protein_name": "Histone H3.3", "gene_name": "H3-3A", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MARTKQTARKSTGGKAPRKQLATKAARKSAPSTGGVKKPHRYRPGTVALREIRRYQKSTELLIRKLPFQRLVREIAQDFKTDLRFQSAAIGALQEASEAYLVGLFEDTNLCAIHAKRVTIMPKDIQLARRIRGERA", "length": 136 }, "evidence": [ { "id": "G3MZM9", "url": "https://omabrowser.org/oma/group/G3MZM9/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "Q7KR10-1", "protein_name": "Probable cytochrome P450 12d1 distal, mitochondrial", "gene_name": "Cyp12d1-d", "tax_id": 7227, "organism": "Drosophila melanogaster", "sequence": { "sequence": "MNTLSSARSVAIYVGPVRSSRSASVLAHEQAKSSITEEHKTYDEIPRPNKFKFMRAFMPGGEFQNASITEYTSAMRKRYGDIYVMPGMFGRKDWVTTFNTKDIEMVFRNEGIWPRRDGLDSIVYFREHVRPDVYGEVQGLVASQNEAWGKLRSAINPIFMQPRGLRMYYEPLSNINNEFIERIKEIRDPKTLEVPEDFTDEISRLVFESLGLVAFDRQMGLIRKNRDNSDALTLFQTSRDIFRLTFKLDIQPSMWKIISTPTYRKMKRTLNDSLNVSQKMLKENQDALEKRRQAGEKINSNSMLERLMEIDPKVAVIMSLDILFAGVDATATLLSAVLLCLSKHPDKQAKLREELLSIMPTKDSLLNEENMKDMPYLRAVIKETLRYYPNGFGTMRTCQNDVILSGYRVPKGTTVLLGSNVLMKEATYYPRPDEFLPERWLRDPETGKKMQVSPFTFLPFGFGPRMCIGKRVVDLEMETTVAKLIRNFHVEFNRDASRPFKTMFLMEPAITFPFKFTDIEQ", "length": 521 }, "evidence": [ { "id": "G3MZM9", "url": "https://omabrowser.org/oma/group/G3MZM9/", "database": "OMA" } ], "glygen_name": "Fruit fly", "common_name": "Fruit fly" }, { "uniprot_canonical_ac": "Q7M715-1", "protein_name": "Taste receptor type 2 member 117", "gene_name": "Tas2r117", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MKHFWKILSVISQSTLSVILIVELVIGIIGNGFMVLVHCMDWVKKKKMSLVNQILTALSISRIFQLCLLFISLVINFSYTDLTTSSRMIQVMYNAWILANHFSIWIATCLTVLYFLKIANFSNSFFLYLKWRVEKVVSVTLLVSLLLLILNILLTNLETDMWTNEYQRNISCSFSSHYYAKCHRQVLRLHIIFLSVPVVLSLSTFLLLIFSLWTHHKRMQQHVQGGRDARTTAHFKALQTVIAFFLLYSIFILSVLIQIWKYELLKKNLFVVFCEVVYIAFPTFHSYILIVGDMKLRQACLPLCIIAAEIQTTLCRNFRSLKYFRLCCIF", "length": 330 }, "evidence": [ { "id": "G3MZM9", "url": "https://omabrowser.org/oma/group/G3MZM9/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q7M719-1", "protein_name": "Taste receptor type 2", "gene_name": "Tas2r115", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MCAVLRSILTIIFILEFFIGNLGNGFIALVQCMDLRKRRTFPSADHFLTALAISRLALIWVLFLDSFLFIQSPLLMTRNTLRLIQTAWNISNHFSIWFATSLSIFYLFKIAIFSNYLFFYLKRRVKRVVLVILLLSMILLFFNIFLEIKHIDVWIYGTKRNITNGLSSNSFSEFSRLILIPSLMFTLVPFGVSLIAFLLLIFSLMKHVRKMQYYTKGCKDVRTMAHTTALQTVVAFLLLYTTFFLSLVVEVSTLEMDESLMLLFAKVTIMIFPSIHSCIFILKHNKLRQDLLSVLKWLQYWCKREKTLDS", "length": 310 }, "evidence": [ { "id": "G3MZM9", "url": "https://omabrowser.org/oma/group/G3MZM9/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q7RTZ2-1", "protein_name": "Ubiquitin carboxyl-terminal hydrolase 17-like protein 1", "gene_name": "USP17L1", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MGDDSLYLGGEWQFNHFSKLTSSRPDAAFAEIQRTSLPEKSPLSSETRVDLCDDLAPVARQLAPREKLPLSSRRPAAVGAGLQNMGNTCYENASLQCLTYTLPLANYMLSREHSQTCQRPKCCMLCTMQAHITWALHSPGHVIQPSQALAAGFHRGKQEDVHEFLMFTVDAMKKACLPGHKQVDHHCKDTTLIHQIFGGCWRSQIKCLHCHGISDTFDPYLDIALDIQAAQSVKQALEQLVKPEELNGENAYHCGLCLQRAPASNTLTLHTSAKVLILVLKRFSDVAGNKLAKNVQYPECLDMQPYMSQQNTGPLVYVLYAVLVHAGWSCHDGHYFSYVKAQEVQWYKMDDAEVTVCSIISVLSQQAYVLFYIQKSEWERHSESVSRGREPRALGAEDTDRRAKQGELKRDHPCLQAPELDEHLVERATQESTLDHWKFLQEQNKTKPEFNVGKVEGTLPPNALVIHQSKYKCGMKNHHPEQQSSLLNLSSTTRTDQESMNTGTLASLQGRTRRAKGKNKHSKRALLVCQ", "length": 530 }, "evidence": [ { "id": "G3MZM9", "url": "https://omabrowser.org/oma/group/G3MZM9/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "Q7TMR7-1", "protein_name": "Monocarboxylate transporter 7", "gene_name": "Slc16a6", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MTQKNSKLCSRANVYTQVPDGGWGWVVAASFFFIEVFTYGVIKSFGVFFNDLMDSFDESNSKISWIISICVFIMTFTAPLSTILTNRFGHRLVVMGGGLLISVGMIAASFSQRVYQMYISIGIVSGLGYCFSFLPTVTILSQYFDKRRSMVTAVASTGECFAMFAFAPAITALKEHIGWRYSLLFVGLLQLNVMVCGALLRPIIIKGPGSPKAIPLEPRREVQYMLENEKTRTSIDSIDSGVELTTSPKNVPSEAKREQEVRVEQQQTLVVGPKHSQKRAPLLDFSILKDRSFICYTLFGLFATLGFFAPSLYIIPLGISLGIHPDRAAFLLSTMAIAEVFGRIGMGLVLNREPIRKIYIELICVILLTVSLFAFTFATEFWGLMLCSVFFGSMVGTIGGTHIPLLAEDDVVGIEKMSSAAGVYVFIQSISGLAGPPLAGLLVDQSKIYSRAFYSCAAGMALAAVCLALVRPCKKGLCQNPHSGENQTDGHRGKALQDIPEDFLEMDLGKCEPRAHMKMDPV", "length": 522 }, "evidence": [ { "id": "G3MZM9", "url": "https://omabrowser.org/oma/group/G3MZM9/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "Q7TN50-1", "protein_name": "Mas-related G protein-coupled receptor member B8", "gene_name": "Mrgprb8", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MDSSIPDPEADLIQLNGSYHTETSPCVIESRVMILLSIIIAFFGLAGNAMVLWLLAFRMRRNVFSVYILNLAGANFLFLCTHTAFSLEKIIVLFHSVHIHIPLLFYTLSTLAYLAGVSMVTAISAEYWLSGIWPYWYQGQRLKHTTTVICTGLWGLALLLSLLEGKSCGFLGSTYNQDVCWKLDFIIVAWLLVLFAVLSRSIQVLLVRIFCGSQRTPVTKLHVTIVLTALVLVICGFPFGIIFYLLYWTTEVYYIMPCNSFHETILLLSYINSCANPIICLLVGSIRHCRFQCGTLRLLLHRAMQDIPEEEGEELEEVVGERVQNSIP", "length": 328 }, "evidence": [ { "id": "G3MZM9", "url": "https://omabrowser.org/oma/group/G3MZM9/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "Q7TPX8-1", "protein_name": "Oogenesin-2", "gene_name": "Oog2", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MNFYSPPTLMELARQCLLRDEYLAISALKDLPNMMFPVMFKEAFIDGHTKILTAMIPVWPFPYLSVGTMLKNLNLDTLKAVLEEIDILISKPVFSSRCKLREITLSHDLVVVWAGSHEVEGLPEFMEQEKPVENSPGYGTKNKLKVTTELQFMEGHLDECSTYLLQWAYQREDSIHLHCRKLKIYGLTKAAVIEMFKIVHAEYIEDLELSCLCLEYLDFLNPYLKQMSNLLSLTLDEIIYTLNIDDYRNLNEEKVITVISHLPTFHHLQELYVHGVIFIECLRCLKKPLEVLSFTDCDLSQSDLDYLPYCLNIFELRSLHLTDVRLSNLLLEPLGFLLERVRHTLKSLQLMSCEMGETHFNALLPALSQCYQLTVVNFYGNELSLLFLKKLLHHTAKLSQLADELYPAPQECYDNRDVVLSHRLENFCSELLDILRAIREPKKVTFGTIKCSKCGGSYVYDLETQCCFFEKNPPWA", "length": 476 }, "evidence": [ { "id": "G3MZM9", "url": "https://omabrowser.org/oma/group/G3MZM9/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q7TQY5-1", "protein_name": "Olfactory receptor", "gene_name": "Or4k38", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MEDSNRTVSSEFIFQGLCSSRQLEIFLLLPFSILYLMAVVGNLFVVILIIIDHHLHSPMYFLLANLSFIDFCLSSVTTPKLTIDLLKENKTISFVGYMRQIVCVHFFAGGEMVLLVTMAYDRYVAICRPLHYSSIMDRQKCIWLVVISWIVGFVHAISQMLLILDLPFCGPRVIDSFFCDIPLVMKLACMNTDTLEILINADSGILATTCFILLLISYTYILLTVQHRSKDGSSKALSTCTSHIIVVLLFFGPIIFIYLWPVSITWVDKFLAVFYSVITPLLNPAIYTLRNKDIKNAIKKLISHK", "length": 305 }, "evidence": [ { "id": "G3MZM9", "url": "https://omabrowser.org/oma/group/G3MZM9/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q7TR72-1", "protein_name": "Olfactory receptor", "gene_name": "Or8k25", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MEKYNLTIVTEFILVGITNHHEFQVPLFGLYLIIYLTSLVDNLGMIILTIVDSRLQTPMYFFLRHLATTDLGYSTAVGPKMLRNFLVDQNIISFYACAIQSSFFGMFIVCEFFILSAMSYDRYVAICKPLLYTVIMSQKACWILVTIPYLYSIIVSLLVNIKIFTLSFCGYNVISHFYCDALPLLTLACSNTHEIEAIILIFSAFNLLSSLLIVIGSYLLILMAILRINSAEGKWKAFSTCGSHLTVVIVFYGTLIFMYLQPTFTHSIDTGKVISIFYTQVIPMLNPLTYSLRNKDVKDVLKKPMEKVHNLFS", "length": 313 }, "evidence": [ { "id": "G3MZM9", "url": "https://omabrowser.org/oma/group/G3MZM9/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q7TSF0-1", "protein_name": "Desmoglein-1-gamma", "gene_name": "Dsg1c", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MDWHSFRIAALLLTSLVVLEVNSEFQIQVRDHNAKNGTIKWHSIRRQKREWIKFAAACREGEDNSKRNPIAKIHSDCAANQPVTYRISGVGIDQPPYGIFIINQKTGEINITSIVDREVTPFFIIYCRALNAQGQDLENPLELRVRVMDINDNPPVFSMTTFLGQIEENSNANTLVMKLNATDADEPNNLNSMIAFKIIRQEPSDSPMFTINRKTGEIRTMNNFLDREQYSQYSLVVRGSDRDGGADGMSAESECSITILDVNDNIPYLEQSSYDITIEENTLHSQLLQIRVIDLDEEFSDNWKAIIFFISGNEGNWFEIEMNERTNVGTLKVVKPLDYEAVKNLQLCIGVRNVAEFHQSIISQYRLTVTLITVTVLNVVKGCVFQPGSKTFIVDSRMEANHTVGEFLATDCETGQATNKFKNVRYRYVMGNNPENLLVVDSGIITLRNRVTMEQYERLNKRYEGTVLSIHDSLQRTCTGTIIMVLCGFWTTTEHPTTSTEKPVTLSITPNVDNVHFGPAGIGLLIMGFLVLGLVPFLLISCDCGGAPGGGAGFEPVPECSDGAIHTWAVEGPQPGGITTICVPQMPPGNANVIEYIDNSGVYTNEYCGREMQDLGGGERTTGFELMDGVKTSAAPEICQEYSGTLRRNSMRECRDGGLNMNFMESYFCQKAYAYADEDEGRPSNDCLLIYDIEGVGSPAGSVGCCSFIEDLDESFLDTLGPKFKKLADISLGKEIDSYPDPDPSWPPQSTEPICPQHMEQLASGHPSISPHFGKTTVISENAYPSGPGVQHPMLIPDPLGYGNITVRESYTTSGTLKPSVHFHDNQQASNVVVTERVVGPISGADLHGMLEIPALRDGTNVIVTERVIAPGSSLPNSLTIPNPRETSNVVVTERVIQPTSGMIGNLSIPP", "length": 911 }, "evidence": [ { "id": "G3MZM9", "url": "https://omabrowser.org/oma/group/G3MZM9/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q803M0-1", "protein_name": "Protein phosphatase 1 regulatory subunit 3B", "gene_name": "ppp1r3b", "tax_id": 7955, "organism": "Danio rerio", "sequence": { "sequence": "MPIELAMSLYLSSDEFLNPRASKYSRPLQPCLNQCKSSKLSFSSLKEQSEFNGVSRALMIPGRAKKHVSFADHKGLALTVVKIFSEFDDPIDIPDNIDNFFTSSLTVSEGKDKLTLDFDQPSADYLKFRQRIENDHVCLEHCMLKEKSIMGTVKVKNISFEKSVKLRITFNTWKNHTDVECQYVKDTYTGSNRDTFSFEASLPEQVPSHERIEFAICYEVNGDTLWDNNQGKNYRIIQSALRKSSNESNGGHQQYSQSDWDIHFDRYGSPRCSRGIFPHWPSYVGYEDIGPYY", "length": 293 }, "evidence": [ { "id": "G3MZM9", "url": "https://omabrowser.org/oma/group/G3MZM9/", "database": "OMA" } ], "glygen_name": "Zebrafish", "common_name": "Zebrafish" }, { "uniprot_canonical_ac": "Q80SW5-1", "protein_name": "Embryonic testis differentiation protein", "gene_name": "Etd", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MDEKNPEAVPRPPEQNTELVPPKKSKSKKPANILIYLIDRHLGRPRNDMDLFEWVWTLK", "length": 59 }, "evidence": [ { "id": "G3MZM9", "url": "https://omabrowser.org/oma/group/G3MZM9/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q80VJ6-1", "protein_name": "Zinc finger and SCAN domain containing protein 4C", "gene_name": "Zscan4c", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MASQQAPAKDLQTNNLEFTPTDSSGVQWAEDISNSPSAQLNFSPSNNGCWATQELQSLWKMFNSWLQPEKQTKEQMISQLVLEQFLLTGHCKDKYALTEKWKASGSDMRRFMESLTDECLKPPVMVHVSMQGQEALFSENMPLKEVIKLLKQQQSATRPTPDNEQMPVDTTQDRLLATGQENSENECNNSCNATEANVGESCSGNEMDSLLIIQKEQHPEHEEGNVVCQFPHGARRASQGTPSHHVDFPSAPTTADVPMEEQPKDLSRENISEDKNNCYNTSRNAATQVYSGDNIPRNKSDSLFINKRIYHPEPEVGDIPYGVPQDSTRASQGTSTCLQESLGECFSENDPREVPGLQSRQEQPISDPVLLGKNHEANLPCESHQKRFCRDAKLYKCEECSRMFKHARSLSSHQRTHLNKKSELLCVTCQKMFKRVSDRRTHEIIHMPEKPFKCSTCEKSFSHKTNLKSHEMIHTGEMPYVCSLCSRRFRQSSTYHRHLRNYHRSD", "length": 506 }, "evidence": [ { "id": "G3MZM9", "url": "https://omabrowser.org/oma/group/G3MZM9/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q80VT8-1", "protein_name": "S100 calcium-binding protein, ventral prostate", "gene_name": "S100vp", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MAQNLTSTEQEIMELLMILQEFSVKKIDKLDVQEVKRLFREELPNFLKAMDEATKNKILNDKGKEMPFDEIWDMIGRMALEYRKKNSNALKD", "length": 92 }, "evidence": [ { "id": "G3MZM9", "url": "https://omabrowser.org/oma/group/G3MZM9/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "Q80XZ1-1", "protein_name": "Polypyrimidine tract-binding protein", "gene_name": "Smptb", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MSRNSPPAAEGNGSKRFKGDSWGTRDPSRLVHILRLPSCVTEGEILCLALPFGEVSNLLFLRAKNQAFVEMSTEESANTMINYYTWMPPVLRGQPVHIQFAHYRELKVSSSPSQEISLSQAGDSREATASSLVAVPGQAAASGQTAVPSQLGAQPCLPPEDSYQAGTVALAPPASAVDTELVVAWQSPVLRILVENYFYRVTLEVLHQIFSRFGTVLKIITCTKNNRFQALLQYAHVMSAERAKLFLDGQNIYDACCTLRISFSGLTNLMVKYNNDKSRDYMRPDLPSDDSQPSPVQVQNMASALPAPAMSSASPYASIALPHTFAIPQAAGLANPEVFKTLHPQAIQEVAMASSSSSSSTAAAAVGAAEIAAAAVPGAEGSMVTSGSPGVGSPVLLVANLNQEKVTPRSLFILFGAYGDVHRVKILFNRKENALVQMADGSQAELALRHLNGHKLYGKALCILLSKHQSVKLPREGKEDQGLTKDYANSPLHRFKKPGSKNFQNIFPPSATLHLSNLPSLVSEEELKNLFSSNGYAVKAFRFFPKNHKMALIRMGSTEEAIQALVDLHGHLLGQNHHMRVSFSRMTI", "length": 588 }, "evidence": [ { "id": "G3MZM9", "url": "https://omabrowser.org/oma/group/G3MZM9/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "Q810J1-1", "protein_name": "Pregnancy-specific glycoprotein 22", "gene_name": "Psg22", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MEVSSELLSNGWTSWQRVLLTASLLTCWLLPITAGVTIESVPPKLVEGENVLLRVDNLPENLRVFVWYRGVTDMSLGIALYSLDYSTSVTGPKHSGRETLYRNGSLWIQNVTREDTGYYTLQTISKNGKVVSNTSIFLQVNSSLFICGRPSPPALLTIESVPASVAEGGSVLLLVHSLPDNLQSLLWYKGLTVFNKVEIARHRTVKNSSEMGPAYSGREIVYSNGSLLLQNVTWEDTGFYTLQIVNRYWKMELAHIYLQVDTSLSSCCDDFNSVQLRINPVPPHAAEGERVLLQVHNLPEDVQTFLWYKGVYSTQSFKITEYSIVTESLINGYAHSGREILFINGSLLLQDVTEKDSGFYTLVTIDSNVKVETAHVQVNVNKLVTQPVMRVTDSTVRIQGSVVFTCFSDNTGVSIRWLFNNQNLQLTERMTLSPSKCQLRIHTVRKEDAGEYQCEAFNPVSSKTSLPVRLTVMNE", "length": 475 }, "evidence": [ { "id": "G3MZM9", "url": "https://omabrowser.org/oma/group/G3MZM9/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q863C3-1", "protein_name": "Gastrin-releasing peptide", "gene_name": "GRP", "tax_id": 9913, "organism": "Bos taurus", "sequence": { "sequence": "MRGREVPLVLLALVLCLAPRGWAAPVTAGRGGALAKMYTRGNHWAVGHLMGKKSVAESPQLHEEESLKEQLREYAQWEEATRNLLSLLQAKGARGHQMPPWEPLSIHQPAWDSEDVSNFKDTGPQHEGRNPQLN", "length": 134 }, "evidence": [ { "id": "G3MZM9", "url": "https://omabrowser.org/oma/group/G3MZM9/", "database": "OMA" } ], "glygen_name": "Bovine", "common_name": "Bovine" }, { "uniprot_canonical_ac": "Q869X2-1", "protein_name": "Probable polyketide synthase 17", "gene_name": "pks17", "tax_id": 44689, "organism": "Dictyostelium discoideum", "sequence": { "sequence": "MTFNNIKDENNDDIAIIGMGFRFPGGGNNPYQFWNQLSNKMDGISKIPTEKWSRSFYEQKYINNEYGGVLKDEEWKNFDPLFFGISPKEAPIIDPQQRLLMTTLWEAFEDANIKPSTFRGSDTAVFIGMMNTDYQRCQFRDISYVNPYITPGTAGSFISNRLSFSFDLRGPSMTLDTACSSSLNAVYLGCQAIANGDSKMAIVGGVNGIFDPCFSMTFSGLNMLGHKGQCRSFDAGADGYIRSEGGGVCILKKYSDAIKDGDRIYCVIKGGSSNVDGYNAKTNIIQPSMKAQGENIEIALKKSGVNPSDIYYIEAHGTGTPVGDPIEIEAISRIFKDNHTPDAPLYIGSVKSNIGHLESAAGIASLIKVALSLKNRSLVPNIHFEKPNPLIKFEDWNIRVVTDEIQFPINKLINMGINCFGLSGSNCHMILSEAPINYDELLKTTNNNSTSSSSNDDKKEYLIPFSANCNISLDKYIEKLISNQSIYKDTILFKDFVKHQTISKSNLIKRKVITASDWDDFLNKRNETTSTSSLTSTISAPASSTPVIYVFTGQGPQWRDMGKALYETESVFKDAIDHCDKLLANYFGYSILQKLLSLESEDSPEIHHPILAQPSIFLIQVGLVALYKSFGISPSIVVGHSFGEIPSALFSDVISLETAVKIVYYRGLAQNLTMGTGRLLSIGIGADAYLEKCALLYPEIEIACYNDPNSIVITGSEQDLLGAKSTLSAEGVFCAFLGTPCSFHSSKQEMIKEKIFKDLSDLPESNVPCVPFFSTITGSQLSHKGFYNVQYIYDNLRMPVEFTKAISNIFNFIEENESYKNAIFLEIGPHPTLGFYIPKCKPSNSTITSKPIIVSPLHKKKEELTQFKLAISTLYCNGVEIDFASGQQLLPTSSSSGGGDISSFKESTNKLPRYQWDFEEYWDEPNQSKMVKRGPSNNLLGHDQFAGNTLMELFIDIDKSAHQYLKGHKIKGKYLFPGSGYIDNILRQFNGQDITIFNLEFSNPFFLKDGVQHHLQTSITPTTKGEFKVEFFIKDNRNSTKWTKTSNGRIGLFKHNPKNNKLDIEKLKSQCSFTTLTKSEVYNKLLLLSLPYGPTFQRVESCSIGDGCSFFKLSMSPCSEFDKDFLNPSIIDCAFHGLLVLSEGPQEIVFDRLQDMKFYSSNVPSTRPQFIYAFAKFDKIEGNSTHGSLNIILEDGTLLISIKNVKCTSLIRLKKQSIKYPSQNVYSHHWQSKDSPLTLIENQLIEEKSSESKINFEKLLNDKLFNYYLIRLLNQSIKSEFIEFDYKTSTVDTLDIGSKNAKLLEKIQSILNPIDSLDQSIDITSLKQAIIVKSSFKNEIKLVEKSIKRIVSLLKGGESEHFSPSNPSSPNDTPRNNSNNCSSKNNAASSDDADDDTNNEETINQLNNEPFNFSNSQFISNQNQLISKTIVNSFDRLINSIEIGEKKLIKIIDLSSIYQNYQLSKLLLLQLNQLLINLSNNNNIEIEYTIPSNTKNIDSITEETKSISNVLNIKYRSFDLQDDLESNGYLNSNYDLIITSLLLVSTNSIDSNEVLSKLYKLLLPKGQLILMEPPKGVLSFNLLFANDFKQSLEIKSEQEIKSLIIYCGFTKIETNLNTKDDEEQQQPPPPSILIVQAEKRDIESMSLTFSSDPKSLNSSYSNCIFIVSKEQKENPTSYIQEYFDITEFFCQNATIIEADDSELLTKTIESGVGKNDIIFFLVSLEELTIENYKQVTMQYTLVNQILLRNNLSTRFALLTYDSQNGGKNYLGSSLIGTFRYFLEFRSLNIFSIDVDKDSIDNLTLFLRLVDLSTIGDRETIVRNNKIFVQKIFKEPKLLSPSNNYEKNTNNLFLYSNSNLDFSFQSKEKLLHGCVEIKVMSTGINYKDSLFYRGLLPQEVFSKGDIYSPPFGLECAGYITRVAPSGVTRFKVGDQVVGFASHSLSSHVTTHQNKIVLKPENISFNEAAAVCVVYATSYYSIFHIGAFIADKESILVHSATGGVGLASLNLLKWKRNQLKKHGNSEISNDASIYATVGSKEKIDYLQEKYGDLITAIYNSRDTEYCDEIKQQSAQGGVDLILNTLSGDYLSSNFRSLSQVGRIMDLSVTQLVENDSLDFSNFKYHVGYNTIDLDRATKYNSKIIRDILTEVFDAISDGSLENIPVKVFPAIQVKTAIEYINERVHIGKIVVDFENFEQDILKPALQEKENPIQLNKVKKLEHTCDTLNNTILITGQTGIAVHILKWIISGSVLNSNKSQQQVTDFIILSRSSLKWELENLINQTKHKYGDRFRFHYKSVNIADLNSTRTAIDQVYSSCKNVSPIKSVLHFATVYEYILPENITQTVIDNTHNPKAVGAINLHNLSIEKDWKLENFILFSSIGAIIGGSKQCAYSSANLVLDSLSNYRKSIGLASTSINWGGLDAGGVAATDKSVASFLEGQGILLVSLSKILGCLDSVFQPSNSHLSNFMLSSFNIDNLLSSAPQMKRKMDHHLTNYKTSSASSDDSLGDSGSTQAKVISTISELLSIHPSKLNLDTRLKDYGIDSLLTVQLKNWIDKEFTKNLFTHLQLSSSSINSIIQRISSKSTSTSTPNPTNTSKQTATKKT", "length": 2604 }, "evidence": [ { "id": "G3MZM9", "url": "https://omabrowser.org/oma/group/G3MZM9/", "database": "OMA" } ], "glygen_name": "Cellular slime mold", "common_name": "Social amoeba" }, { "uniprot_canonical_ac": "Q869Z5-1", "protein_name": "Uncharacterized protein", "gene_name": "", "tax_id": 44689, "organism": "Dictyostelium discoideum", "sequence": { "sequence": "MSHLTPKPNVLNVYGAGTPNFVKVQILLEEKNIPHVYHKIDFSKNEQFDPEFLKFSPNNKIPAIVDNTVEPNGISVFESAAILMYLSEKHQFTDLYADFKTDPALHAKHLEFLFFQMSGVGPMTGQLGWFLRQPEPKNTQAIERYSEEVKRLYRVLDKILSTNTWVAGEQYSIADISLLGWALYFLKGYYDDHITREQFPNVYRWLDLAAKRPAIIKVLETIQPKQK", "length": 227 }, "evidence": [ { "id": "G3MZM9", "url": "https://omabrowser.org/oma/group/G3MZM9/", "database": "OMA" } ], "glygen_name": "Cellular slime mold", "common_name": "Social amoeba" }, { "uniprot_canonical_ac": "Q86AE3-1", "protein_name": "Probable polyketide synthase 9/36", "gene_name": "pks9", "tax_id": 44689, "organism": "Dictyostelium discoideum", "sequence": { "sequence": "MGNLKNINLKEKGVAIVGIGFRIPSGNNENSISSPDDLFNNLKNGFDGVSSTSERWSDNFHKLGEISSPNAGLLPFKEWKSFDPLFFGINPSEAPLIDPQQRLLLKCTWEALEDASIDPISIRGTNTSVFIGSSTIDYLHTNKHQDSVLKNAIAQSTSAISNRISYCFDFNGPSLSIDTACSSSLNAVSQGYHSILNGTSNMSIVGGVNLILDVDIIKAYSILSMLSKTHGKCKTFDESGDGFTRGECVGVVVLKNLQDAVKDGNRIYCVINGSSSNVDGNGNMDKVNFYSPSKQSQFNNINSAFKSTNDKLSINDIQYIEAHGTGTKTGDPIETEAISMAFKNRDKSTPILIGSIKSNIGHCEAGSGVASLIKCCLMFKYQCFLPNIHFKNPNPLIKFNEWNLKVVTSPIPFNKRNNEKPVSMMINNFGVTGSNCCLLISEFKNNNNFKENINLESQSVNDRVLIPFSANSSNSLNQYQSKFKNIINNQFNFIDFTANQIYSKSNFLYQRSVVIASNSNELFENISNKKQIQTKNSIISNMSFKGKNPITIFVFSGQGSQYPKMALELYNNEVIFKKSIDLIDSKLSKYYGFSVWEKVKTIKDDDLTSIHDPIFAQPALCMISVSLFELYYHWGVNPSFILGHSLGEISASYCSGMIDLDTFCYTVYQRSIAQSKTNGCGRMLSINISDEEFKSMYSQKYPQIEIACYNSPQSIVVAGNESILNEISKELKEKEIFTTMLGSLSSFHTSSQQCTKDSILQLNIESNQPKVPIFSTVTTNLFNESNRFNSQYVYDNIIKPVKFTQTISNIYKHIESNQLNNEIVFIEIAPHPTLLFYIKQMVPSSLNESVSVYSALHKKKNDVEEFQQTISNLYCQNGYNINFKCQFNNKKSNQSINLPLYQWDEELYFTQAQTLEQHRKEGPPIDHLGTSNSYNSPFNNSYRTSIDIKNKPFLYLKGHMVKGKYYFPGCGYIDNIIQLYKNQDIFISFIEFKTPLILIEGINQYLQTNIQQTGKSEYRAQFHFKDQKSNEWIQSSNANFQLLDHGNDIPPKYNIKEIIENKCNLSKLTKNELYTHIKSKTGLNYTGVFQGVTECYIGGDCTLSVVSLESQTNSFLNIPILDTCLHGMIGLSNDQCQIVFDKAIGFKYYSSNIPANLKDYKDSVYVYSHLKSKSVDSFFGSIIVMLSDGSVLYEIEEVVCKSLIPIKDSLKIEYPNDELYKVHLQSKDSPIPTPSSFKSIIYENDFFHSALNIPEDLFKYISTLFYKDIIKRCPEININKINSHSVNEIISSFSKISKHERLFRFVFETIKENGILNSLEENDDAYFEFNEVIIKSSRIISKLLFPLESDNDNEDLPQSLFQNGLMDKIYKCRYLRKKNQMISHVIKHSIKEIINNNIIIRILEFGGGTASLSVEVIEEIIALLQENPNYQVEIEYTWSDISPAFIADAKNKINKIINDAAITNGFNVIYRPLKIDESLIETQSINPSYYDFVIMSNVLHVVKNIKQAVEQMYQLLTPNGQLLFLEPPYKSVLNDSIVGSFEQWWSFTDTDIRKDRCSMSQQSWCQLLKTCNFKDIAMSKECIFVGIVIHAQKPPISLLNSQPKRDNIIIYGGGNPIFVENIKLYSNSKSLIQIETIQEFNQLLSQSTITNDSIIYFIKTLETLSLDNFKQITLEYIEINRKLLQINSLCKHVLIVSDSRKTNYLASSVVGAARYFDEFQQLKLNTLDFDYDSTQNYINSNNKDMVQFINILTDSKTNVHKEMIIINNKVYYEIVQKEKNLKLKYNSESFENQNNLMCSLSPNLEYQLQSKQIKLRDNQVEVKTIATGINYKDYLNFSGSNSNGDDNTGLPQFGYEFSGIITRVGNNVKDYKVGDNVFGLSNSCTSSHIVTNYKKIQIKPSNLSHNEASSIPIDYLTSFMSLFNIGSLNIEDNESILIHLGSDGFGLSTFEILKWKGFNSNLFVTVNSYETKRYLQDNYGDFITGIYSNTDKSYVTEINKKLIKLGSKKKGVDLILNTLPSDFMDSNFKLLAKYGRIIDLTSNHLNQSEFLKNINFKYNHGYHNFELSLIQKNKIHKCLYEISNAFENGELKTIPIKEFTNLNIKDAIKYITNNKIEKITVSHDHEIYSDIIYRSLDEKEFSILKSNYQINSNNLGKNILVTGQSGIILEILKWIIKYSNINTIENVIILSRSSLKWELELLINETKLSNNNIKFHFKSVDIGDSEQVDNAINEILNENQQITNIDSIYHFAFQQITCKVQEINMKHLDISHGAKSMGAINLHNQSIKRNWKLINFVMASSAISLIGSTDLCTYVCANALLDSFSKYRESLGLPSTCICLGAIESTGFVSKNESVSVFLDGGGFHPTPINQVLGLLDLQIQNAGKFTNSMLSNFKPSKFKNNQQTSLFLKFDYLMNLKNNSEETKIENTGNKNIDELFIEKVSELFSMDESKINKNLRLIDYGADSLIIVQLKNWIDKEIGINLITIQQLQNNTISTSMKMILNSLMKNNQNIDDNNKDLPSNRIDYWKNEMKFEESIKPISNEIQSRNNSEKIILLTGTTGFLGGFLLFNMVRLDSCKLIYCLIRNKSKSNNPLDEIINNLKYHQLYEKLNQSQISKIIPIIGDLSMNKLGLSNDDYETISKNVNLIINPGADINQKSSYQDCKLVNVNGVKEIIKLSLSSLKQRIPIVNFSSFSVFFNQSLDKNFDESVLPSIDNIDNLPTEYMKSKVVGEYILLEASKKYNIPSILIRPPSIFLNPETGIGHISDFSLLSIQSCYELGYYPNQFENDFILINTITWLSNNITNIIMNDNCWTDSKMNIYNVHGKQIQSSLIIKPLEKHFNCKHINTNDWIDMVNNSNKKSCIKLKSFHSLDIILKSENNRYKPNENQSISLSTKSLLESMGSYNTDLEITDKMIISHINQIFNLNETI", "length": 2931 }, "evidence": [ { "id": "G3MZM9", "url": "https://omabrowser.org/oma/group/G3MZM9/", "database": "OMA" } ], "glygen_name": "Cellular slime mold", "common_name": "Social amoeba" }, { "uniprot_canonical_ac": "Q86AF8-1", "protein_name": "Uncharacterized protein", "gene_name": "", "tax_id": 44689, "organism": "Dictyostelium discoideum", "sequence": { "sequence": "MFSKFSIKENKPKKVKSNSSKGFNNNEINSTNNNNNNNNNNNNNNNDSDNFINNNDSNNNNNFNNNNNNNSNNINNKTEDSNDISLLINQFIGSSPAPSTCSGSDKFSIKPKKIVTPSKRKNSTSGSDIIDFNNCNNNNNSKSNSDSNNNKYNNSNSNNNSCNNTNNGNERKMKGYDYGNNNSNNNYSSSSRDYNSNNNSSPRDYNNNNNNNNNNNNNNNNNSNNNSPRDYNNSRDYNNNNTNNNSSPRDSNSNNNRNSSSRDFSNNNSSPRDYNNSRNSNNSFLNNNNNNNNNSNNSNDNSPRDYNYSSSNSSPRDYNNNNDTFSKKRNNVGNSILEIKSNPTSPRIKPIMVWPRSSPRIVNKLPPVQSLVDLTEIEMIDDNNNNNNNNNNNNNNNNNNNNNNNSNNNNNKSGSNNNFSDSDSDKDNYNNNNNTNNNSFNSDSDNYNNSNNNNSNSNSNSNSNSNSNSNNNNNNNNNSNNNNNNNNNNNSNNSNKSNNNFSNIKILEKRRKSINEISDNLTTRNIEEIDSKMAHEFEHPFLEKLIFAGQRPPFVECDDYFLKRYKNQFQYYLDISMKSIINTRDIGEGDDDDEINSVPFKCTLCSYEYDEENNNENTNGFIDEADKIYNRSNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNSNSNNNNNNNFYDKKYFKNNYFQHLLSKHLNQIKAKGIQDTNVYNDEANIPLGSKKCDHLECSEIILKNEFTKHIKKLHHHHKDEDIDICPRCKILKKSIQKRIVKFSKKKQEKDDDNNSKPVSNKVATISHNPSPNNIDKDINNNNNNKNNKNNTNNLENDNNDNSSNNNYLENEEEPEIVFQDIKPNNNNNNNNNNNNNDDNNNDNNDNNDNENNNDNNNDNENSNNNNNNS", "length": 901 }, "evidence": [ { "id": "G3MZM9", "url": "https://omabrowser.org/oma/group/G3MZM9/", "database": "OMA" } ], "glygen_name": "Cellular slime mold", "common_name": "Social amoeba" }, { "uniprot_canonical_ac": "Q86BK9-1", "protein_name": "Mediator of RNA polymerase II transcription subunit 22", "gene_name": "Dmel\\CG32971", "tax_id": 7227, "organism": "Drosophila melanogaster", "sequence": { "sequence": "MSDSKDEALLKSFKTQLKDNVLSMLLNFEELLKLVSPRTPGQITNDTEQELNAFEMQVRAGNFVRAGEALIKLVHDVKEYQIIYDYSNIEEEMDRQSEAMHAKVTEYDQTLIKMVKDLEEELSELEYEYYEKSGGPDLDSKDLLV", "length": 145 }, "evidence": [ { "id": "G3MZM9", "url": "https://omabrowser.org/oma/group/G3MZM9/", "database": "OMA" } ], "glygen_name": "Fruit fly", "common_name": "Fruit fly" }, { "uniprot_canonical_ac": "Q86IJ5-1", "protein_name": "Uncharacterized protein DDB_G0272718", "gene_name": "", "tax_id": 44689, "organism": "Dictyostelium discoideum", "sequence": { "sequence": "MPPHGHHHHHHGHHGHHEHITITPVYAPPQVVQPIYAPPPVVQPVYVQPPVVYPQATIVLETGHHHGHHHHHGHHGHHDHHHHGHHGHH", "length": 89 }, "evidence": [ { "id": "G3MZM9", "url": "https://omabrowser.org/oma/group/G3MZM9/", "database": "OMA" } ], "glygen_name": "Cellular slime mold", "common_name": "Social amoeba" }, { "uniprot_canonical_ac": "Q86IV6-1", "protein_name": "DNA replication ATP-dependent helicase/nuclease DNA2", "gene_name": "", "tax_id": 44689, "organism": "Dictyostelium discoideum", "sequence": { "sequence": "MNFFEKKNNNNNNSSNNNNNNNNNKNNNNKNLDKNNSSDRNNNNNGDKNNLKPTQKSLIDLWFQVDDEDEEYELSSLSNDGGSSFNSFKVNNRDTSIGSDIYSKTITPSSLALSTSSLISSTLTPPTQSPPFSKKNEKTSSFLNSPSSQKSKSNNSNVKEKLSPQYSSSSQLSDFFKKKKRPLLDNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNTISSLNTNSNNNSSGSSNGSSSSSSGGGNKSSNNKKQKVSQSTSSTSLKEKQSQQSILSYLNPTPSLPTPIFDKPIERSDSNLATSSFSKLNFDDIPLDDEELSQKINTPSPKLILKNTFSSTPTQKSPSLSSTPPNKIKITDKKLPNSSSSSSSPPPSSAKSKLSHRSQSSPLSPLITNLNQNKSNEFDDINFNFNIPSPLKEINNKPNIKSNSKETLTPLTQIFHSSSPPPSIIIESSPSVCFSPTPTKNQSPTLSNLSPTFSFLSDTSPVKSPSQLFEFTFDDPLSPKLISSNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNTNTFISKNNLINLFNEQSNQENVSTTTTTTTTTTTSTSTNNNNNNRYERVLIINVFYEVTQIFNNSNDKIHKKTLSGFSESIGESREIQLLDEWIYTPVRPGDIVNVIGEFDDNGEIIINNIQNLLILHPDILITGTELGGSLTCTRRSVLKEQIRVGNSNSSTVPIFGSIVHEIFQECLKNNRFHLDDINTFKQEIIGKSTFQLGLSSLGETQDTALNHLENWLPTIDKFAKTFILPSSSSSSASSLKKNLIEINSEKWHLSISKILEIEENIWSLMYGLKGKIDSSLEIKLVKQQQDEKQSKQSKQSKKKKQQTTSPNNNNNNNNNNNNNNNNNNNNNNNNNNGPTTCYLNVPFEIKTGKPYQIPYISHSSQVLIYTLLMNDRYDQDIEMGILYYLKSQEFKSVGLNYGLLHPILFERNQIRSLIVSRNLLAYFLNLNSQPLLKPNPILPEMLRDYHSCTKCYSIDPCVLYHKAIENGDQFTSSLGDLFLEKTNHLSSIHINYLKNWNKIISLEYSIKNNKRKLIWNKSRKFGEKNNSCIGELILISEEYSEITETFSYRFRVNPDKLLNSSISEGDYLLISVEDKYYGMGSGQLSNIINDIITITCREKLSEPPSLLSDYTTPNCNNNDPSYFGNYRNKPLIYIEYEDADQQQQQQQQQQQQQQQQQQQQQQQSQKQQKQKQPNFTQLRGLNNYVNNSKLTPFKWRVDIDEQLSGLSIVKSNLFNLFLKENQKLRSLIVDLEAPIFDKLEQENYWKSIDFQNDYPLLNIDQRNAIIKTLSAKDYSLIHGMPGTGKTTLVISLIHILWRLGKKVLITSFTHTSLDHLLLKFNKQYPNIEMLRVASSLNQIDPSLHRFTLEKQSFGNITQSKQYLERQQLVATSCLGINHQCLLKMQFDYCIIDEASILSQPISMGPILKCKSFVLVGDHHQLPPIVNNKEAGKLGLDISLFKQLSTSHPSSVSNLYHQYRMCNSIMSLSNHLIYNNRLVCGNQSISNLSLQTNYYHNNNNTTHIDLLDHINNWPQIICNPNSSVIFVNTDQLNNSTESSNGDLFYNQTEANIVAILTNCLINKLNINQSQIGIITPIRFQLNFIKKSILKYLSIENNNNNNNNNNNSNNNNNNSNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNQNNNQNYLKKIENLDILTIDKFQGKDKDCIIISFVRSNEKKEIGELIKDWKRMNVAFTRAKKKLIFVGSKSSLSKFPFFLDFFEFLDSKNWIYNLNNKIQF", "length": 1838 }, "evidence": [ { "id": "G3MZM9", "url": "https://omabrowser.org/oma/group/G3MZM9/", "database": "OMA" } ], "glygen_name": "Cellular slime mold", "common_name": "Social amoeba" }, { "uniprot_canonical_ac": "Q86JI5-1", "protein_name": "Probable polyketide synthase 5", "gene_name": "pks5", "tax_id": 44689, "organism": "Dictyostelium discoideum", "sequence": { "sequence": "MDMKLNDIENENFINQMKGVAIVGIGFRIPSGNSENSISSPDDLFNNLKNGFDGVSSTSERWSDNYHKLGEISSPNAGLLPLNEWKSFDPLFFGINPSDAHHIDPQQRLLLKCTWEALEDASIDPISIRGTNTSVFIGSSTIDYLHANKHPDLILKNAIGFSPSTLSNRISYCFDIHGPSLSIDTACSSSMNAVTQGYHSILNGTSNMSIVGGVNFVIDVETIKGFSYLNMLSKTHGKCKAFDESGDGFTRGECAGVVVLKKLDDAIRDGNRIYCIINGISSNIDGNGIADKANFYSPSKQSQFNNINLAFKSTNGKISVNDIQYIEAHGTGTKTGDPIETEAISMAFKNRDKSTPILIGSIKSNIGHCEAGSGVVSLIKCCLMFKYQCFLPNIHFKNPNPLIKFNEWNLKVVTSPIPFNRNNEKSVSMMINNFGVTGSNCCLLISEFKKQDYESYENNIGSINKNILVPFSANSPKSLDQYQSKIKNIINNQFNFIDFANNQIYSKSNYLYQRSVVIANNSNDLVNKILNKKHIQTKNPIISNMSFKGKNPITIFVFSGQGSQYPKMALELYNNEVIFKKSIDLIDSKLSKYYGYSVLEKLRSIGDDDTTSIHDPTIAQPAMCMFSVSLFELYKHWGVNPSFILGHSLGEIPTSYCSGMIDLDTFCYTVYQRSIAQTKTHGNGRMLSINISDEEFKSMYSQKYPQIEIACYNSPQSIVVAGNESILNEISKELKEKEIFTAMLGSLSSFHTSSQQCTKDSILQLNIESKKSKVPTFSTVTTNLFNESDPFNSQYVYDNIINPVKFTQTISNIYKHIESNQLDNDIVFIEIAPHPTLSFYIKQMVPSSLNESVSVYSALHKKKNDVEEFQQTISNLYCQNGYNINFKCQFNNKKSNQKINLPLYQWDDELYFAQTQVLEQHRKEGPPIDHLGLSNSYYSPFKNSYRTFIDIKNKPFQYLKGHMVKGKYYFPGCGYIDNIIQLYKNQDIFISFIEFKTPLILIEGINQCLQTNIQQTGKSEYRAQFHFKDQKSNEWIQSSNANFQLLDHTIEMPPKYNIEEIIKNKCTLARLTKNEIYTHIKSKTGLNYTAMFQGATECYIGVDCTLSVVSIESQTNSFLNIPILDSVFHGNISLINDQCQIVFDKVHGLKYYSSNIPNDYKDKSVYVYAKLKSKTSDSYSASFTVLLSDGTVVYEIDEAFSKSLIPIKELLKIEYPNDELFSINLQPKDSPIPAPSTFKSLIYENDRFNAEPPMVENLFQYISTIFYKNIINRCPEINIDIIKSLSIDEIISNFSKISKHERLFKYVFETIKENGILNSLEEKDDTYFVFNEVLIKSSRVISKLLFPLENDNDNEDTPQLLFQNGLMDKVYKCRYLKNKNQMIAHIIKHSIKEIINNNIIIRILEFGGGTASLSVEVIEEIVTLLQENPNYQVEIEYTWSDISPAFIVDTKNKINKIIKGAGITNGLNVIYHPLTIDESLVELQSIKPSYYDFVIMSNVLHVVKDIKQAVEQMYQLLIPNGQLLFVEPPYKSIICDSLFGSFEQWWAFTDTDIRKDHCCLSQDGWYKLLKWSNFESIEMSTESKFMGSVIQAQKPSFTSLINQQPKYDNIIIFGNNCPNFIDNIKPFSNFNEFIQIETIQEFDQLINKSTITNDSIIYFIKSINQLSLDNYKQATLEYIEINQKLLQINSLCKHVLIVNDSRKTNYLASSIVGAARYFDEFQQLKLHTLDFDYDSTQNYLISKNNKMVQFINNLIDSKTNVHKEMIIINNKVYYEIVQKEKNLKLKYNSESFEQQDNLMCSLSPNLEYQLQSKQIKLRDNQVEVKTIATGINNKDYLVYSGLEGSVNSNTPQFGYEFSGIITRVGNNVKDYKVGDNVFGLSNSCTSSNIIVNHERIQIKPSNISHIEAASIPIDYLTSFMSLFNVGCLNIEDNESILIHLGSDSFGLSTFEILKWKGFKSNLFVTVNSDEIKQYLLNNYGDLITAIYSNTDKGYVSQIKNKLIEQGSNDNGVDLILNTLPSDFMDSNFQLLAINGRIIDLSNDHLNQSEYMKNVNFTLNRGYHNFDLMSQRNSRINRSLLTISKAIENGELKLIPIKEFSNSDINDAIEFIIEENRIDKIVVSHDHEVYQELYAKFSNENDFSILKSNYQINSNNLGKNILITGQSGIILEILKWIIKYSNINTIENVIILSRSSLKWELELLINQTKLSNNNIKFHFKSVDVGDSEQVDNAINEILNENQEIINIHSIFHFAFTQIACKVQEINMKHLDISHGAKTMGAINLHNQSIKRNWKLINFVISSSIASLVGSTDQCSYVCANALLDSFSKYRVSLGLPSTSINLGAIESTGFVSKNESISVFLDGSGIIPTPINQVLGLLDLQIQNPGKFTNSMVAKFNPLNFSNNEQINLLLKMDYIFNLHSNGYTKVKESAGSKNVDELFIKKISDLFSIDESKINKDIRLIDYGADSLVIVQLKNWVDQEIGFNLITIQQLQNNTINVSIKIILNFLKKINK", "length": 2512 }, "evidence": [ { "id": "G3MZM9", "url": "https://omabrowser.org/oma/group/G3MZM9/", "database": "OMA" } ], "glygen_name": "Cellular slime mold", "common_name": "Social amoeba" }, { "uniprot_canonical_ac": "Q86KS1-1", "protein_name": "DNA cross-link repair 1 protein", "gene_name": "dclre1", "tax_id": 44689, "organism": "Dictyostelium discoideum", "sequence": { "sequence": "MSDDEDDINLYITRSKNNENKKTNKNRLIDNNIQKTKTTTAVLTTRTTTTTTTTTASTQLKWDYGDEDDDDYSAPKDIDEEQSSKQFNYQNNQIVVKQDHDDYSAPKDMDEEQSSRQFNYQNDQTLVKQDDDHDDYNEPKDIDSQSLIDEDCDFEFDNSDFFFDDGTTNNNDNNNKNNKNNNNNNNNNNNNNNYNNNNNKNYKRKYYQSYNNSNNINNNNNNNNDKFEKRLSDLKKTGKEEAKKRGYQVRKTPTKEKKIPPSFKVIDGTNFLVDGFQYKSEDFTHYFLTHFHSDHYVGITKTWSFGNIYCTEETGKLVSHKLGVDQRYIVKCEWNKLIEIQGVKVAFLDSNHCPGSALILFIIPLRNKDGEIIGEESILHTGDFRYNQSMNNYPLLKGRTISKLYLDNTYCDPQYVFPPQPEIIKQVASIVRKENDGETLFLFGTYVIGKERILLEIAKQEGKPVHVSNEKYAILCCLSTCLDINKFTTNELITPFRAVTMSMLSYHNMLSLLDSSNNKYKRVIGFRPTGWTQAKKSITYLNRGPTTFYSVAYSEHSSFNELRDCIDHFRPTQIIPTVDCDSPIKVKNILAHFSDLYEKKKQLTIASFFSAQPVTNFFQSFFKSKSEPIIDEDNKKLIPITTTTTTNINTLTATDTTTTKIKTSNTLIKDEFTDDLIWDCSDDLISDRKLLTQSDNSSALCKIEKEENFNDLSENNNNSNNNNNNNNNNNNNNNNNNNNNNNNNKLIIENDIKEEIIDFDDPVFISQQKWIEKQIYNNNNNSNNNNFTTPTKTNGNLSNNAKLNLTPTQTQTQTPTQNNKKQKTTNVSPTSYNSNNSSQQSGLKRSKSDPNVKKNQLQTSQPPSQSLITSFFQKCASPTSLFSATPPTPSITTTSNQSTKNKNSTTTTSTSTSNNKPFKN", "length": 920 }, "evidence": [ { "id": "G3MZM9", "url": "https://omabrowser.org/oma/group/G3MZM9/", "database": "OMA" } ], "glygen_name": "Cellular slime mold", "common_name": "Social amoeba" }, { "uniprot_canonical_ac": "Q86KX6-1", "protein_name": "TNF receptor-associated factor family protein DDB_G0272348", "gene_name": "", "tax_id": 44689, "organism": "Dictyostelium discoideum", "sequence": { "sequence": "MEFELEDITIEQSSFTNNNSNNNNNNNNNSNSNNNNNNNNNNINNNNNHNNNNKNNSNNKNEINNQLDIPISNLVVDKENISKKYFCTICSDLLVNSFHADKFKAVQCKNGHYTTCLNCWEKHLEKKKNCIQCGVDVESIESLSSNLLVTQKFTTFKIHCPNSFFDTIDFIKDEVNGCKEIIQINELEEHLKECQYGFISCKNCEEFSKLPFQEFTQCPDFRKNTKEQHDLICPYVKISCEYCGDIINKINKESHNANWCQEITIKCLDCHLPFKKKEINQHQKSFCPETIIQCRYSKGGCNAMIRRSKLSQHLTEGDNHHQFISNILNQQDLKINELELKNTEFCLLLNGQNKKITELEILFKELNDSILIQKQQQKQQQQQQQQQQQQQQQQQQQQQSQQQQSQQQQQSQQQQQSQQSQQNNNSNSHFINNNNNNINNVQMSDSPNGGSLPQAVYKNKWVISNYSEQEQQGISKDYIKSPLFKIGNSTFFLKWFPFGKKKLNYCSIFLYKTQDDKSIIVNYYIHLVNNQISDEVYEKRGCQKYDSENGSAGYGSSQFIKRADLLNDANGFLINDSITIEIEIFATEEILPLQS", "length": 595 }, "evidence": [ { "id": "G3MZM9", "url": "https://omabrowser.org/oma/group/G3MZM9/", "database": "OMA" } ], "glygen_name": "Cellular slime mold", "common_name": "Social amoeba" }, { "uniprot_canonical_ac": "Q8BI41-1", "protein_name": "Syncytin-B", "gene_name": "Synb", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MTGFWVLCFVLFPSSLSYPESWMPLVNLTHHILRDTNSSLFSNCWVCLSTQTQRSLAVPAPLSIWTDTPMKLHLTYSVRPFSGSFSISDIERRLRLFRPLTASYSFHNPDRRAIAFLQLVSSTGIFRIITRITSVIYPHKDRFFESAQRPLWGPLFTETVLRSQAPLCISRFFKVSAYATFVGNLSASLCNYTMHISPSTSHENLDLSTTHTFKQAMKRPDAKWKNPLRFSGPPSLIFSKPAYYPCPTDIKHCHTSPATPWMHCPQAPFGTCYNLTLFEPDNSTHPVTMSVNPTHFKVKLQGHRDPYPLSHYQPLTGAALSGQYSVWENEITVQENWDITSNIFSHLLSFSYAFCLNSSGVFFLCGTSTYICLPANWSGVCTLVFQYPDIELLPNNQTVPVPLFASVLSSDSVLRPKRSPHLFPFLAGLGISSALGTGIAGLATSTLYFQQLSKVLSETLEEIAASITTLQNQIDSLAGVVLQNRRALDLITAEKGGTCLFLQEECCFYVNQSGIVRDAARKLQERASELGQHSDSWGQWPDLGRWLPWLTPFLGPLLFLFFLLTFGSCLLNCLTRFVSQRLGSFVQDTAKRHVDSILQNFQYKKLPQDSPDEDTIPT", "length": 618 }, "evidence": [ { "id": "G3MZM9", "url": "https://omabrowser.org/oma/group/G3MZM9/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q8BYG0-1", "protein_name": "Tetratricopeptide repeat protein 24", "gene_name": "Ttc24", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MLSSRQYGLSDVLRALEESRKLADADRSTDQGLLGPFYNDLGMGYFQLQLFPLAVEAFLQALPLCRQPSEQATVLQNLGMTHNVLGNYWEAQEFHQKAASLHGSVGQRWEQGRSFSGLAFSLSQLGDHRAAWDSYLHALQAAQDTGDVKGQWQACEGLGAAAARLGQHDQALKYYKEALALCQHEPSSVRERLVAKLADAMRTFVAQEKIAQARFLPSAPGKLQTSRKAKTSARVQSSAEDAQESQWEGEASEGGHEKKEMEGLVNTATVLGPQRQNRATTHLPSGGPSPSGEEYPFIIAPKKLRVSRSSTWAKEALGRNFQRTRIQSGLCSIM", "length": 334 }, "evidence": [ { "id": "G3MZM9", "url": "https://omabrowser.org/oma/group/G3MZM9/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q8C1N8-1", "protein_name": "Alpha-defensin 22", "gene_name": "Defa22", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MKKLVLLSALVLLAYQVQTDPIQNTDEETNTEEQPGEEDQAVSVSFGGQEGSALHEKLSRDLICLCRKRRCNRGELFYGTCAGPFLRCCRRRR", "length": 93 }, "evidence": [ { "id": "G3MZM9", "url": "https://omabrowser.org/oma/group/G3MZM9/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q8C1P2-1", "protein_name": "Alpha-defensin 21", "gene_name": "Defa21", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MKTLVLLSALILLAYQVQTDPIQNTDEETNTEEQPGEDDQAVSVSFGGQEGSALHEKLSRDLICLCRNRRCNRGELFYGTCAGPFLRCCRRRR", "length": 93 }, "evidence": [ { "id": "G3MZM9", "url": "https://omabrowser.org/oma/group/G3MZM9/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q8C5Y2-1", "protein_name": "Mitochondrial sheath formation-associated protein", "gene_name": "Misfa", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MIVLGWMLFVGLATYMGTFPEAMPPTLKWKERLPGQENKARRRIQALEEELLL", "length": 53 }, "evidence": [ { "id": "G3MZM9", "url": "https://omabrowser.org/oma/group/G3MZM9/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q8CDW1-1", "protein_name": "Protein FAM228A", "gene_name": "Fam228a", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MADTKTSKCDEHFSVEKLKEWPEPESVSLMELLAREDIDEAVHAVLFRENYVVKRLDTYLQHLAVFKERRKEMLHKKWVENVVQPLQQRITDKITSYRRPGKNQVKYEHCLKQTNKPTKVSSSCLFQKQQEFREAKGTSYQHGRGKTHDTQKEAKETEKGLSFTPFSLRPHCSSPRERQRASARLMQSKPGGRNRYKGASSEKPVFTLKSHLPKEEKTVSRSQLVFERQFRASRLSQDIKEAEKKGLVVGTGPQRPRSWAAADSVPRPSLVGRRVMTAEILGEHLVSLHQAARSGLQWP", "length": 299 }, "evidence": [ { "id": "G3MZM9", "url": "https://omabrowser.org/oma/group/G3MZM9/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q8CEK3-1", "protein_name": "Serine protease inhibitor kazal-like protein, minor form", "gene_name": "Spinkl", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MSSTWIKFLFILTLVLLPYSVFSVNIFAGPENVIKEPNCTMYKSKSECSNIAENPVCADDRNTYYNECYFCIEKVVEKLKYRYHGICIYK", "length": 90 }, "evidence": [ { "id": "G3MZM9", "url": "https://omabrowser.org/oma/group/G3MZM9/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q8IZP1-1", "protein_name": "TBC1 domain family member 3", "gene_name": "TBC1D3", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MDVVEVAGSWWAQEREDIIMKYEKGHRAGLPEDKGPKPFRSYNNNVDHLGIVHETELPPLTAREAKQIRREISRKSKWVDMLGDWEKYKSSRKLIDRAYKGMPMNIRGPMWSVLLNTEEMKLKNPGRYQIMKEKGKRSSEHIQRIDRDVSGTLRKHIFFRDRYGTKQRELLHILLAYEEYNPEVGYCRDLSHIAALFLLYLPEEDAFWALVQLLASERHSLQGFHSPNGGTVQGLQDQQEHVVATSQPKTMGHQDKKDLCGQCSPLGCLIRILIDGISLGLTLRLWDVYLVEGEQALMPITRIAFKVQQKRLTKTSRCGPWARFCNRFVDTWARDEDTVLKHLRASMKKLTRKKGDLPPPAKPEQGSSASRPVPASRGGKTLCKGDRQAPPGPPARFPRPIWSASPPRAPRSSTPCPGGAVREDTYPVGTQGVPSPALAQGGPQGSWRFLQWNSMPRLPTDLDVEGPWFRHYDFRQSCWVRAISQEDQLAPCWQAEHPAERVRSAFAAPSTDSDQGTPFRARDEQQCAPTSGPCLCGLHLESSQFPPGF", "length": 549 }, "evidence": [ { "id": "G3MZM9", "url": "https://omabrowser.org/oma/group/G3MZM9/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "Q8K072-1", "protein_name": "Receptor expression-enhancing protein 4", "gene_name": "Reep4", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MVSWMICRLVVLIFGMLYPAYASYKAVKSKNIREYVRWMMYWIVFAIFMAAETFTDIFISWFPFYYEFKMAFVLWLLSPYTKGASLLYRKFVHPSLSRHEKEIDACIVQAKERSYETMLSFGKRSLNIAASAAVQAATKSQGALAGRLRSFSMQDLRSIPDTPVPTYQDPLYLEDQVPRRRPPIGYRPGGLQGSDTEDECWSDNEIVPQPPVRPREKPLGRSQSLRVVKRKPLTREGTSRSLKVRTRKKAMPSDMDS", "length": 257 }, "evidence": [ { "id": "G3MZM9", "url": "https://omabrowser.org/oma/group/G3MZM9/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q8MP30-1", "protein_name": "Uncharacterized histidine-rich protein DDB_G0274557", "gene_name": "", "tax_id": 44689, "organism": "Dictyostelium discoideum", "sequence": { "sequence": "MEIKYFLVLLVGFLLVLPSIVNPYRKGVTITNQQPKINIYQLDVNNPHNPNNNPHNPHNPNNNPHHPHHLHHHHHHHHHHHHHHHHHHHHHHHHHHPHHPHHHPHHHHHPHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHPHHHPHPHPHPHPHPHLHPNPHPHPHPHPHPHPHPHHHPNPNPHPHPHPHPHHHHHHQEASECLSYQGNRNRLFIKRDY", "length": 233 }, "evidence": [ { "id": "G3MZM9", "url": "https://omabrowser.org/oma/group/G3MZM9/", "database": "OMA" } ], "glygen_name": "Cellular slime mold", "common_name": "Social amoeba" }, { "uniprot_canonical_ac": "Q8NG83-1", "protein_name": "Olfactory receptor 2M3", "gene_name": "OR2M3", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MARENSTFNSDFILLGIFNHSPTHTFLFFLVLAIFSVAFMGNSVMVLLIYLDTQLHTPMYLLLSQLSLMDLMLICTTVPKMAFNYLSGSKSISMAGCATQIFFYTSLLGSECFLLAVMAYDRYTAICHPLRYTNLMSPKICGLMTAFSWILGSTDGIIDVVATFSFSYCGSREIAHFFCDFPSLLILSCSDTSIFEKILFICCIVMIVFPVAIIIASYARVILAVIHMGSGEGRRKAFTTCSSHLLVVGMYYGAALFMYIRPTSDRSPTQDKMVSVFYTILTPMLNPLIYSLRNKEVTRAFMKILGKGKSGE", "length": 312 }, "evidence": [ { "id": "G3MZM9", "url": "https://omabrowser.org/oma/group/G3MZM9/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "Q8NGV6-1", "protein_name": "Olfactory receptor 5H6", "gene_name": "OR5H6", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MFLYLCFIFQRTCSEEMEEENATLLTEFVLTGFLHQPDCKIPLFLAFLVIYLITIMGNLGLIVLIWKDPHLHIPMYLFLGSLAFVDASLSSTVTPKMLINFLAKSKMISLSECMVQFFSLVTTVTTECFLLATMAYDRYVAICKALLYPVIMTNELCIQLLVLSFIGGLLHALIHEAFSFRLTFCNSNIIQHFYCDIIPLLKISCTDSSINFLMVFIFAGSVQVFTIGTILISYTIILFTILEKKSIKGIRKAVSTCGAHLLSVSLYYGPLTFKYLGSASPQADDQDMMESLFYTVIVPLLNPMIYSLRNKQVIASFTKMFKSNV", "length": 325 }, "evidence": [ { "id": "G3MZM9", "url": "https://omabrowser.org/oma/group/G3MZM9/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "Q8R264-1", "protein_name": "Vomeronasal type-1 receptor", "gene_name": "Vmn1r215", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MNWNNIIHTIIFLSLTGPGIVGNMLIFIRHIYMPALGTEKKPVDLIVIHLAFSNMITICTTGIKDIATVFYFRNFLGDIGCKAVVFLARMARGLSICTTCLLSVVQAITISPRTSLWTKLKPQTACQIIPFILVFWIFNGLISSNLLSYIKGGSSLNRSVAATFIGHCYMLQSRHTIKWIFLSLMTLRDVIFQSLMGWSSGSMALNLYKHHKRVLYLYSSRFANNSPPEIRATWSVLILMTCFLLFYWADFILSFYHGFTVTHESILLNIKVFLELGYVSFSPYVLISRYIHPPNVFHAH", "length": 300 }, "evidence": [ { "id": "G3MZM9", "url": "https://omabrowser.org/oma/group/G3MZM9/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q8R272-1", "protein_name": "Vomeronasal type-1 receptor", "gene_name": "Vmn1r220", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MVLQFIKKTIFLFMTMVGILGNMSVSVHYMFSWWGSPEKKPIHLILTHLTFTNIILLLAKGLQKTIIVFGLRNFLDDIGCKIIVYLERVARGLSICTSSVLTVVQAIIISPRASGWRRLRPKSAWHILPFFSFFWILNAFISVNLIHSIRSKGMNTSQHKNSDDYCYLTPESQKIKWIVLPLMVLRDAVFQGAMGGASGYMVFLLHKHHQHVLYLQNSKLLYRTPPELRAAQSVLLLMLCFLFFYWTDCALSLFLSLSLGDSSLMINIQGFLTLGYAIFSPFVLIQRDGLIPVCWHAQ", "length": 298 }, "evidence": [ { "id": "G3MZM9", "url": "https://omabrowser.org/oma/group/G3MZM9/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q8R278-1", "protein_name": "Vomeronasal type-1 receptor", "gene_name": "Vmn1r213", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MLALRNYIQINTPWCMCLFVTPLTPCLPEYWDPDSLRVEGPTESSLRHNTASCTLKNTIMQNVQFRSMSSITDAFFKMYLHTRKEEMILKILKEITFLIMTVLGILGNMSVSVNYMFSWWGSPEKKPIHLILIHLIFTNIIILLVKGLPKTIAAFGLRNFLDDIGCKIIVYMERLARGLSICTSSLLTVVQAIIISPRASGWRRLRLKSAWHILLFFLFFWILNALISVNLIHSTTNTRLNVSQLKSDDNYCYFMLPIQKIKWIVLPLMVVRDAVFQGAMGGASGYVAFLLHKHHQHVLYFQNSKLLYRTPPELRAAQSVLLLMLCFVFFYWTDCAFSLFLTLSSEVNILMVNTRDFLTLGYATFSPFVLIHRDGLLVECRHVQ", "length": 384 }, "evidence": [ { "id": "G3MZM9", "url": "https://omabrowser.org/oma/group/G3MZM9/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q8R2A9-1", "protein_name": "Vomeronasal type-1 receptor", "gene_name": "Vmn1r229", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MDFGNLAMGIVLSLQSALGILGNFSLLFYYLVLYNKERTLKIIDIILIHVFTSNSLIIFSKGLPEVLAVFGWNDLFDDVGCKLIMYVRRVSRSMSISMTCLLSVFQAITISTRNSCWKEFKEQTAKFMGLFISLCWILFMLVNMLFPVYTSTNRNSKNKTQKKDIEFCHSVGRDKMVDIMYTAFCVFPEVLFSLLIVSSSTTMIVILYGHKKRVQHILHTHASPRTSAENRATQTILILVCTFLAFYTLSSVLQGYVALSHDPSWWVMNITTIISMGFPAIGPFVMSRDFTVSRFCFTCIGNLKLP", "length": 306 }, "evidence": [ { "id": "G3MZM9", "url": "https://omabrowser.org/oma/group/G3MZM9/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q8R2B6-1", "protein_name": "Vomeronasal type-1 receptor", "gene_name": "Vmn1r178", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MSAHDKSLKTTDDMTLQILLLCQFVVGTVANVFLFLHNISPVLTGSKQRPRQLILSHMSVANALILFLTSFPDMMAFAPRNSPTHLKCKLEYFSRLVARSTNMCSTCVLSIHQFVTLVPVNRGKAILRASVPNLTSYSCYSCWFFSVLSNIYIAIKVTGPQITDNNTDSKSKLFCFTSGFSVGIFFLRIFHDGTFMSIMVWTSVSMVLLLHRHRQRMQHILTPNQDARGQAETRATHTILMLVVTFVSFYLLNFICIIFYTFSIDSRLFMSHFSKVFAAGFPTISPLLLIFRDPKYPCSVLFNC", "length": 304 }, "evidence": [ { "id": "G3MZM9", "url": "https://omabrowser.org/oma/group/G3MZM9/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q8R2B8-1", "protein_name": "Vomeronasal type-1 receptor", "gene_name": "Vmn1r64", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MLSQNKTLKTMEVLALQILLLCQVVVGTVGNIFLFVHNFSPVLTDSRLRPIQVILINLAVANAFMLLLFAYSYDLIDFVPRKPPTDLKCKLAYFFNMVAQGTIMCSTCLLSTYQFVTLVPGNWARVMFREISPKVVSYCCYSCWLFSVLNNAYMPMYVSGPQKTHNDSDSKDNWICSISGVSVDMNFLRFSHDIIFIGIMAWTSVSMVIHLNRHHHRMHYLHNPNQINRGHAETKAAHTIMMLVVTFVSLYILDCICSLFHISFVESRLWLIDVIELLHLSFPTVSPFLLICRDPMGPCSLLFIVGLEIHVTVGAITEEQ", "length": 320 }, "evidence": [ { "id": "G3MZM9", "url": "https://omabrowser.org/oma/group/G3MZM9/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q8R2B9-1", "protein_name": "Vomeronasal type-1 receptor", "gene_name": "Vmn1r59", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MEMLALQILLLCQVVVGTVGNILLFVHNFSPVLTDSRLRPIQVILINLAVANAFMLLLLTYSHDMIDFVPRKPPTDLKCKLAYFFHMVAQGTIMCSTCVLSTYQFVTVVPGTWARVMFREISPKVVSYSCFSCWLFSVLHNAYIPMNVSGPQKTHNDSDSKGNSICSISGVNVDMHFLRFSHDIIFLGIMAWTSVSMMIHLNRHHQRMNRIHKVNQNNRGHAETRAAHTILMLVVTFVSLYILNCISILFHISFVESRLWSRHVIKVLALSFPTISPLLLIFRDPRGHCSLLFSVGLEIHVTGGVITEEQ", "length": 310 }, "evidence": [ { "id": "G3MZM9", "url": "https://omabrowser.org/oma/group/G3MZM9/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q8R2C0-1", "protein_name": "Vomeronasal type-1 receptor", "gene_name": "Vmn1r62", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MEVLALQILLLCHVVVGTVGNILLFVHNFSPILTDSRLRPIQVILINLAVANAFMLLLFAYSYDLTDIVPRKPPTDLKCKLAYFFHLVARGTIMCSTCVLSTYQFVTLVPGTWARVMFSEISPKVVSYCCYSCWLFSVLNNAYMLMNVSGPQKSHNDSDSKSNSICSISGVSVDMNILRFSHDIIFLSIMAWTSVSMVIHLHRHHQRMNHIHKVNQNNRGHAETRAAHTILMLVVTFVSLYILNCISILFYISFVESRLWLRYVTKLLALSFPTISPLLLIFRDSKGHCSLHIMSVWKST", "length": 300 }, "evidence": [ { "id": "G3MZM9", "url": "https://omabrowser.org/oma/group/G3MZM9/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q8R4R9-1", "protein_name": "Protein phosphatase 1 regulatory subunit 14C", "gene_name": "Ppp1r14c", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MSVVTGGGEAAGGTSGGGARVFFQSPRGGTGGSRESSSHSGSSREDSAPVATVAAAGQVQQQQRRHQQGKVTVKYDRKELRKRLVLEEWIVEQLGQLYGCEEEEMPDVEIDIDDLLDADSEEERASKLQEALVDCYKPTEEFIRELLSRIRGMRKLSPPQKKSV", "length": 164 }, "evidence": [ { "id": "G3MZM9", "url": "https://omabrowser.org/oma/group/G3MZM9/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "Q8R4V1-1", "protein_name": "NFAT activation molecule 1", "gene_name": "Nfam1", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MESWLLRRGARVRCLHPPSWLPAWCFLCLLPVPQTLQLTGLVSLTHTSLPIMVSLANTDVFFSCRIEDFTRLQRDLPVKLFHTDIHGRRRWEKQINCQHRPGMENHTRDCMVKLSQANTSATGIYYFIVEGEETYQSDGVVILVRDTVYQPPAFKVQEALMLGFTSLMSVLGVLGTALLLWKKKQISVLGKHTAKTCSGLKSTVGTTKPPAESVYTSLQRRETEVYACMKEETGSPVFSQSPATKEKLNRFEDDNEFNLVYENL", "length": 264 }, "evidence": [ { "id": "G3MZM9", "url": "https://omabrowser.org/oma/group/G3MZM9/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q8T277-1", "protein_name": "5'-AMP-activated protein kinase subunit gamma", "gene_name": "prkag", "tax_id": 44689, "organism": "Dictyostelium discoideum", "sequence": { "sequence": "MWYPGDEDEEFTSIIENIEKKETQEIKIKTEKLRQASLNQLPIEQSEGVGGGELSEYNNNTTNNNTPTNTTTTTNTNTTTMNNSNNNNERILSTSNGFDIRLPPNSIEQPSPSFISSSQDGVLTVDPLAVDGEKGNKESQSPPNGDNQILNNNNMFFKDITSLPSTDNKSSTNTNNNNNENPLKQTISSSPSKSTTTTTTSTSTTTTPSLSSLSSNNNNNSNSNNNYINHSSISTVSEGLENLNLKSGIKKIDSETEKYIEEGKQVFVNFLKGHTCYDVIPISGKVVVLDTKLAVKSAFYALEENGIKSAPLWNSEQHDFTGMITVSDFIDILLYYYKKPKSNNIFQDMGIHRIETFWREISVERPSSLISTEPETNLYDAASLLLCYKIHRLPVVDKKDTNSILHILTHSRILAFMMKSFPQLPEKLLSIPIGSLGIGTFATVVTVMTHTPLVEVLELLSEKKISAVPIIDSETSKIVDVYSKSDVTLMSKQGILSPSDLNLPVHQVLSTFTKLWQRPEQIYTCTRFDKLGDVIERCIKKRVHRLVCIDSSKKVEGILSLSDILNYLLNDVKSINH", "length": 577 }, "evidence": [ { "id": "G3MZM9", "url": "https://omabrowser.org/oma/group/G3MZM9/", "database": "OMA" } ], "glygen_name": "Cellular slime mold", "common_name": "Social amoeba" }, { "uniprot_canonical_ac": "Q8VEU4-1", "protein_name": "Olfactory receptor", "gene_name": "Or14j2", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MIVENITTMRGFLLMGFSDNHELQILQALLFLVTYLLGSAGNVIIITITTLDPQLQSPMYYFLKHLSILDLSSLSVTVPQYVDICLTQSGYISYAQCMLQIFFFTGFAWGEVAILTVMSYDRYVAVCLPLHYEVIMGPSKCRWAVTAVWLSSVIPGTLYIASIFSIRFCGDRIIHQFFCDVPQVLKFSCSDDYLVTVGVADFLSAVAFACFIGIVNSYVHIFSTVLRMPSAESRSKVFSTCLPHLFVVLLFLSTGIFAYLNPTSDSPTALQFLVSIFYTVLPPTLNPVIYSLRNETIKSVIRKLLLSSKFTG", "length": 312 }, "evidence": [ { "id": "G3MZM9", "url": "https://omabrowser.org/oma/group/G3MZM9/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q8VFX0-1", "protein_name": "Olfactory receptor", "gene_name": "Or5b101", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MENRTEVRCFILVGLTNDPSLQLPLSITFLLIYIITLIGNLGLILMILLDSRLHTPMYIFLGNLSLVDFCYSSTVTPKVIAGFLTGDKIMSYNACASQMFFFANFGDVENYLLASMAYDRYVAVCKPLHYATTMTTHMCASLVIGCYICGFLSASIYTMDALSLSFCESNVIHHFFCDVLAVMIVSCSDSHVNELILIYVVSFNMFFALIIILISYMFIFTNILKIHSSAGYHKAVSTCASHFTAVSIFYGTIIFMYLQPSSSHTMDTDKIASVFYTMVICMLNPLVYSLRSKDVKSAFTKIVLRSK", "length": 307 }, "evidence": [ { "id": "G3MZM9", "url": "https://omabrowser.org/oma/group/G3MZM9/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q8VY69-1", "protein_name": "Vesicle-associated membrane protein 723", "gene_name": "VAMP723", "tax_id": 3702, "organism": "Arabidopsis thaliana", "sequence": { "sequence": "MAQQSLFYSFIARGTVILVEFTDFKGNFTSVAAQYLENLPSSNNKFTYNCDGHTFNDLVENGFTYCVVAVDSAGREIPMAFLERVKEDFYKRYGGEKAATDQANSLNKEFGSNLKEHMQYCMDHPDEISNLAKAKAQVSEVKSLMMENIEKVLARGVICEMLGSSESQPQAFYIKRTQMKRKKWFQNMKIKLIVLAIIIALILIIILSVCGGFNCGK", "length": 217 }, "evidence": [ { "id": "G3MZM9", "url": "https://omabrowser.org/oma/group/G3MZM9/", "database": "OMA" } ], "glygen_name": "Arabidopsis", "common_name": "Mouse-ear cress" }, { "uniprot_canonical_ac": "Q8VZ67-1", "protein_name": "Uncharacterized zinc finger CCHC domain-containing protein At4g19190", "gene_name": "", "tax_id": 3702, "organism": "Arabidopsis thaliana", "sequence": { "sequence": "MDGEGEGSGIRLSKRFAGGKVTGGSLEVDYKTKSGTAWSHSFLNQKPWHPLSYPNQRRKWIAEQTHAQHDRRAEEVAREFAQEQEFFKQAALISKKEREKIETMKAVSFMYVRPPGYDPESAKAAEYKDEKHKGQGSSTQDPVADDNVGSRPEESQGGGERTQERKKPRPKDVFGRALPTEEEFEVLKNAPRMETGIPGRVKPFAVEVRNVKCLRCGNFGHQSGDRDCPLKDAVMPNEELRLKRDDPLTAIIAHTDPSEPLKWELKQKPGLSPPRGGFDPDDPNQQIVAEDIFDEYGGFLEGSIPIEILKSMSSDKKRKSKKNKRHKKHSSRTVEETDESSTGSEDSREKRGSKKRKKLKKKSKKQYDSDSLSFEGSGSDSYRLSRRRHTKHVDPSASLKSEVYHQGNSHREKHYYDEKHQKRKEIVDRPSASSDDSDYYRSNSSRKKRSEDDYKSHHRERKQVHSNDPVSEKSQKQHYSESGKIQRVEKEHRYDERRHRYVDMESENRNRSEKKPRYDDRDSEKHHRSVKGKEKHVYEASDDPEEFSDRYRSTKKTESDSESNRRSRKKKHELSSEEEEGESRKHRYSTNRRRN", "length": 595 }, "evidence": [ { "id": "G3MZM9", "url": "https://omabrowser.org/oma/group/G3MZM9/", "database": "OMA" } ], "glygen_name": "Arabidopsis", "common_name": "Mouse-ear cress" }, { "uniprot_canonical_ac": "Q91V82-1", "protein_name": "Beta-defensin 8", "gene_name": "Defb8", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MRIHYLLFTFLLVLLSPLAAFSQKINEPVSCIRNGGICQYRCIGLRHKIGTCGSPFKCCK", "length": 60 }, "evidence": [ { "id": "G3MZM9", "url": "https://omabrowser.org/oma/group/G3MZM9/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q923B3-1", "protein_name": "Neurotrophin receptor-interacting factor 1", "gene_name": "Nrif1", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MASTLPTTWPHESVKFEDVSLTFTEEEWAQLDFQQKCLYREIMMENYSNMISVEHHFSKPNVISQLEKAEDCWPMQREIPQDTLPECSWPSPDPGMNSFPSKSPLMKIEVVEVLTLNKDVAGPRNALIQSLYPEDLNPGNLKPAQQPSKRLTDTEASRQKFRHFQYEESAGPQKAMSQLRKLCHQWLQPNTRSKKQILELLVLEQFLNALPEKFRVWVESQHPEDCKAVVALLENMTSVSKDDASLACSSEATDQLKEKRKGVATLPVTFAAEVPAEEPVTFQDVAVDFNEEEWRLLGPTQKTEYHDVMLETLGNLVSVGWEPTLGNRELTPDSPIPVVKPIHDPNTNDLSRNGTQSTVFESILEDGVKEMHSIESNQVGNLQEKGHPQKKFSESSKSQDQTSRHKSQGSLNEVLPRKYVKVKQKGTGKRKGRTNTISMTRGLRIRKQQKDSVEWQGRSGSTPVTHGSSIKKQQQGSEQGKPGTSRDPITLTVPAKVYQKATGSEESIFMDSSDAMVPDVPPKIHQKGPEWHKVGESNNSMLQGSSVQNHQMESGAGRASDNSLLTHALPVKSHQKGYKEGNVQGNRNSWKHIKPHQKGSKGERVEELSTSEKHVPYVKNHLKTSERGKDREINASIKCDPYIKTYYRGSDVGRLRRANNCRKAFSLHAQQISFIKIHKGSQVCRCSECGKLFRNARYFSVHKKIHTGERPYMCMACGKAFVQSSSLTQHLRIHSGERPFECSECGRTFNDRSAISQHLRTHTGAKPYHCERCGKAFRQSSHLTRHERTHTGERPYVCIKCGKAFTQSSHLIGHQKTHGIKFKKQPKL", "length": 828 }, "evidence": [ { "id": "G3MZM9", "url": "https://omabrowser.org/oma/group/G3MZM9/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q924S2-1", "protein_name": "Inactive 2'-5' oligoadenylate synthetase 1C", "gene_name": "Oas1c", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MENGLCSIQARELDEFICDYLFPDTTFLTELRADIDSISAFLKERCFQGAAHPVRVSRVVMGGSYDEHTALKGKSEAKMVLFFNNLTSFEEQLKRRGEFVEEIQKHLCQLQQEKPFKVKFEVQSSEEPNSRSLSFKLSSPELQQEVEFDVQPAYDVLYELRNNTYAEPQFYNKVYAQLIHECTTLEKEGDFSICFTDLHQNFMRYRAPKLWNLIRLVKHWYQLCKEKLREPLPPQYALELLTVYVWEHSNKNQEKVTTAKNFRTFLELVAYYKNLRIYWTWYYDFRHQEVCAYLCRQLKKARPLILDPADPTRNVAGSDLQAWDLLAKEAQTWMQSSCFRNCDMSFVPTWDLSPERQECAFQ", "length": 362 }, "evidence": [ { "id": "G3MZM9", "url": "https://omabrowser.org/oma/group/G3MZM9/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q925U0-1", "protein_name": "Oocyte-secreted protein 1", "gene_name": "Oosp1", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MKPFVGLLGLLLLLSFMKTCADDWTAISLQCADHWFHLRIRPTIFHNIFMEPDEVFLGIGCPVTTTWPNDTYEFIYRTYSCGIANKVLCDVTLLKTQLTYISKNASLQAEMSLSCVMHNQSPHFCEAESRGDFTGDPPGWTEDMRARRDEQTVPMVQPNLSTSSEDHHVSTEPWASETSRSEAAEVPSFMDQNFSVFHFSRM", "length": 202 }, "evidence": [ { "id": "G3MZM9", "url": "https://omabrowser.org/oma/group/G3MZM9/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q94490-1", "protein_name": "Ubiquitin conjugating enzyme E2 B", "gene_name": "ubcB", "tax_id": 44689, "organism": "Dictyostelium discoideum", "sequence": { "sequence": "MAAHKRLQKEITDMLKTPPSWCSAHLVDDNLQKWKATVQGPEGSPFEKGVFSMDIDIPADYPFKPPTLKFTTKIYHPNIKTSDGAICAEVFSTWSPQLKILDVLTTIRSILTDPNPDNPLETEIAQQFKTDRNAFNKTAKEWTKKYAK", "length": 148 }, "evidence": [ { "id": "G3MZM9", "url": "https://omabrowser.org/oma/group/G3MZM9/", "database": "OMA" } ], "glygen_name": "Cellular slime mold", "common_name": "Social amoeba" }, { "uniprot_canonical_ac": "Q945S5-1", "protein_name": "Vacuolar cation/proton exchanger 4", "gene_name": "CAX4", "tax_id": 3702, "organism": "Arabidopsis thaliana", "sequence": { "sequence": "MSSISTESSSNLSLLENGGGGSDKPTAETSRRVRRTVSASSLIRKRSDLKLISRVRWEFMRRILTNLQEVLLGTKLFILFPAVPLAVVAHRYDCPRAWVFALSLLGLTPLAERISFLTEQIAFHTGPTVGGLMNATCGNATEMIIAILAVGQRKMRIVKLSLLGSILSNLLFVLGTSLFLGGISNLRKHQSFDPRQGDMNSMLLYLALLCQTLPMIMRFTMEAEEYDGSDVVVLSRASSFVMLIAYLAFLIFHLFSSHLSPPPPPLPQREDVHDDDVSDKEEEGAVIGMWSAIFWLIIMTLLVALLSDYLVSTIQDAADSWGLSVGFIGIILLPIVGNAAEHAGAVIFAFRNKLDITLGIALGSATQIALFVVPVTVLVAWTMGIEMDLNFNLLETACFALSILVTSLVLQDGTSNYMKGLVLLLCYVVIAACFFVSNSPSSKLLF", "length": 446 }, "evidence": [ { "id": "G3MZM9", "url": "https://omabrowser.org/oma/group/G3MZM9/", "database": "OMA" } ], "glygen_name": "Arabidopsis", "common_name": "Mouse-ear cress" }, { "uniprot_canonical_ac": "Q96AK3-1", "protein_name": "DNA dC->dU-editing enzyme APOBEC-3D", "gene_name": "APOBEC3D", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MNPQIRNPMERMYRDTFYDNFENEPILYGRSYTWLCYEVKIKRGRSNLLWDTGVFRGPVLPKRQSNHRQEVYFRFENHAEMCFLSWFCGNRLPANRRFQITWFVSWNPCLPCVVKVTKFLAEHPNVTLTISAARLYYYRDRDWRWVLLRLHKAGARVKIMDYEDFAYCWENFVCNEGQPFMPWYKFDDNYASLHRTLKEILRNPMEAMYPHIFYFHFKNLLKACGRNESWLCFTMEVTKHHSAVFRKRGVFRNQVDPETHCHAERCFLSWFCDDILSPNTNYEVTWYTSWSPCPECAGEVAEFLARHSNVNLTIFTARLCYFWDTDYQEGLCSLSQEGASVKIMGYKDFVSCWKNFVYSDDEPFKPWKGLQTNFRLLKRRLREILQ", "length": 386 }, "evidence": [ { "id": "G3MZM9", "url": "https://omabrowser.org/oma/group/G3MZM9/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "Q99N64-1", "protein_name": "Germ cell-less protein-like 2", "gene_name": "Gmcl2", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MGLLVSRVLRCRDSSLLEPQPEAIAGASYIPGSRKRKRNSLEELATSSNVHGPQNQGMYPHQVLNYIYWKRVKISSNDAYQNLFLDGHDSDIKIRALGRTWCLHKVFLCQSGYFANILKGTWRESHHGVINLIIKNEDIDTRSLHFVFGALYTDADLSITPLEVPQVLAAACLLRVDRVIQQCEGIMKETINRNTVCSYYLAAETYRLKAVKTRCFEWLLCNLMVHPSVALYKEVDLKLMYLLALSSDLLVMQKEIDVYTTLKIWMFLYLNPCWNGTMKQLLQHANNWLSTHMAYVDNISFLESEEGLIFQPVFKKLRFQHIICDLTSTTILEQDRLIPMAWLSPIYKQQWLTLLRTQEYGVIGPQVINEQELEECTMRCGTMIPKDGRYTWKWSVGRLGFPLRVTFTRQCVILRQRCQRCDGSACHNHIRNVIFRITLVCFDSNKRVTFRKTTGYKILTFEYKEEQIVMKLDSDVLTFPMCIFCNFLFVNLGNAENK", "length": 498 }, "evidence": [ { "id": "G3MZM9", "url": "https://omabrowser.org/oma/group/G3MZM9/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q9C7P4-1", "protein_name": "Putative zinc finger CCCH domain-containing protein 9", "gene_name": "", "tax_id": 3702, "organism": "Arabidopsis thaliana", "sequence": { "sequence": "MADAGDNQQEAERRSDETESRSIKEPKEKEDEDENPQDQIQSKERMRQSSPYPVRPGKKDCQFYLKNGLCRYRSSCRFNHPTQRPQELPVRICKHIMDRNVAEPMYQDWRESESERRFDERTQRTFGDERTQRRYGIEYSGARPEKRSKIVPDFQMRDPRHHDTEWRFERERMERIERQRREAEENLQEQRQRDSIERQRREAEENLQEQRQRDSIERQRREAQENLQQQRQRDSIERQRREAQENLQQQRLQDMPENHNVDDQQNLQEQRRISIEKERTEARLRLEQIRPTVSFPINEFIRAVVLLRELIENWDDKAWKK", "length": 321 }, "evidence": [ { "id": "G3MZM9", "url": "https://omabrowser.org/oma/group/G3MZM9/", "database": "OMA" } ], "glygen_name": "Arabidopsis", "common_name": "Mouse-ear cress" }, { "uniprot_canonical_ac": "Q9C8M4-1", "protein_name": "DNA-directed RNA polymerase subunit 12-like protein", "gene_name": "NRPB12L", "tax_id": 3702, "organism": "Arabidopsis thaliana", "sequence": { "sequence": "MDLQQSETDDKQPEQLVIYVCGDCGQENILKRGDVFQCRDCGFRILYKKRILDKKETRIGV", "length": 61 }, "evidence": [ { "id": "G3MZM9", "url": "https://omabrowser.org/oma/group/G3MZM9/", "database": "OMA" } ], "glygen_name": "Arabidopsis", "common_name": "Mouse-ear cress" }, { "uniprot_canonical_ac": "Q9CQK8-1", "protein_name": "Small proline-rich protein 2A1", "gene_name": "Sprr2a1", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MSYYQQQCNQPCRPPPVCPPPKCPEPCPPQVWPGPCRPVMCFEPCLPSVWPGPCRPVVCYEQCPPQPWQSTCPPVQFPPCQQK", "length": 83 }, "evidence": [ { "id": "G3MZM9", "url": "https://omabrowser.org/oma/group/G3MZM9/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q9CWP4-1", "protein_name": "Lymphocyte antigen 6K", "gene_name": "Ly6k", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MAFLVALLVVLGLQLVQSNALTCHVCEAQNSYACSNPSQCPGEKKFCLLAVTRIFERFFYVSKQCTRRCPTPVVSPPSTNPPSEPKEFLIEKPMPFLFYKCCQWDSCNGEGPPTDQLLKEQPGKASGRRHRYIELLLTGFMVLTANGLSALCLL", "length": 154 }, "evidence": [ { "id": "G3MZM9", "url": "https://omabrowser.org/oma/group/G3MZM9/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q9D541-1", "protein_name": "Coiled-coil domain-containing protein 7A", "gene_name": "Ccdc7a", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MKCAKHPSTISMKLTSVPELPYKKGLLNSSPKPKEKHNAKSKYGKNESMVLRSPPTGESIVRFALPIPLSKTKDKISADEMVRRITTNLKMVVSNLEDTYGACYDNGEKAAEKSEAEGLSIGDDVSSFLLCCSQFTSQLEEAVKEECGALESLYKWFQQQVNQMEEISKDQSNLEELQSDGKTASLNIVQIAKLARKFEDFKSRLKTRKEVMQTKNEDKEIMAETLKHYGLMEKQIEEFITSHSALESQTETESQSGTPSVTTRMARMIKIFENQSTMLEKALNDQQTIESKYKQLETDFQMLIMEKTLLEAEIRRLREIERVKSAAKEEQTKKSGKSEKKKFKEKEKNLSPNREFKSIEELLQIQKEAELLKTEKKTLQGQLKWALEEAERNKTQLEFVLHQKMEMFKEESKTKVGQSQNKSKVKIEDSKDSLPKKSDTQLGGQRKDQISSDQSKRPKKKQLADIDPSAVEDFPPETFKSFTVMPLIEEHRESISSQPKEEMAKASEQSEAEDIEGPLEIPSESSNEDDDLLPEDESPMMEQVTDVGRYKSIYISAEPIDTMSLISRTQSEMETLEAINYDNVLNEGEEQDKKIGKDSDTGRKSKRKRSSKIRKLSTHEEESDIVHYEEATKAKVPSKKRASDPYGDEAYESRGSVSKAQTYTKKQGTHQRGRGSASDAYGDEAYESRGSISKAQTYTRKQGTHQRGRGSVQEEESDTVHYEEVTRAKVPSKKQASDPYGDEAYESQGSVSKAHTHTKKQGTHQRGRGSVHEEESDTMNYEVPRKSKISSRRKGFALPITHQVEMHSSESQGSISKSNTETKKQGTHKRGRDSDADGARTPVSQGSDSKADTERKKHRSKEESTISKDSIPVLDEVQDKTFEHQESGLRLEVQAKKLTFSSQNIHNEESATDIKVEYQNVPSSSQVQLKKQKPLGGEIFTTHFVVPAESHAQLYQTHTPETQIERGTTSGTARLTTIPVEHPKKEASPDNLFPEKKLYITRAPTQTKKQYPPWDAKAETQKKTVKEVQGISEPQTKLNPTMSGIILHLDMDRVVETDLENLEETIVPHVLRSELEIGTDAKNMPETPTSREAVRTEAKGNQDVTISIAKGMKLIGKLKDQHGLSSFASKDTISPGKSLIKSSRDNQDDSLLETKPQENTSDKYHPSKTFPTKVINMLPFSEKSLGSTSANVDVAPKPVYRASRGRSRISKALQQLLKTSEHLKPTSTKNQNADLEKHLYISVRSANKHTQKDKKHGQSNNQKLKKQGALSSTKKQKHKEQPKTETIVENNDKFDDNLMMTTSSPNIKIIKELSKTLNLDGGDIELSDFVFKTASAAKKLENKGPSKTKNLNKESSRDIHILHLTTSAIRTLLLDEEAKIRSLEKKLMKQSTILQKSVSSMKKFMFEEPSRETKMKRKKREKRKIVVKSPHILPITTTQKHTIKEKSEISNLEKPIVRGTDILKKSTSARKKRVLKGKSKSATLPKKCDNFPFDLVRSSSDSSKQEVEEQPKPGNVDKKVSDDSYSPDISTTPTKKHTLKGQSKSRTIYEKGVDLPNNLVLSKSASSIQEFEEQPQPGNVDKKVSDDSYSPDISTSPTKKHTLKGQPKSENSDEKGIKRPNNLHMSASVARKRLLKALSTIP", "length": 1642 }, "evidence": [ { "id": "G3MZM9", "url": "https://omabrowser.org/oma/group/G3MZM9/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q9D5R2-1", "protein_name": "WD repeat-containing protein 20", "gene_name": "Wdr20", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MATEGRGKETNEIKTHFTTREGLYRLLPHSEYSRPNRVPFNSQGSNPVRVSFVNLNDQTGNGNRLCFSVGRELYVYIYKGVRKAADLSKPIDKRIYKGTQPTCHDFNHLTATAESVSLLVGFSAGQVQLIDPIKKETSKLFNEERLIDKSRVTCVKWVPGSDSLFLVAHSSGNMYSYNVEHTYGTTAPHYQLLKQGESFAVHNCKSKSTRDLKWTVGEGALNEFAFSPDGKFLACVSQDGFLRVFNFDSAELHGTMKSYFGGLLCLCWSPDGKYIVTGGEDDLVTVWSFLDCRVIARGRGHKSWVSVVAFDPYTTSVEESDPMEFSDSDKNFQDLLHFGRDRANSTQSRLSKQNSTDSRPVSVTYRFGSVGQDTQLCLWDLTEDILFPHQPLSRARAHANVMNATGLPAGSNGSAVTTPGNSVPPPLPRSNSLPHSAVSNAASKGSVMDGAITSGVSKFALLSLHDRKERHHEKDRKRNHSMGHISSKSSDKLNLVNKAKTDPAKTLGTSLCPRMEDVPLLEPLICKKIAHERLTVLVFLEDCIVTACQEGFICTWARPGKVSKFQP", "length": 567 }, "evidence": [ { "id": "G3MZM9", "url": "https://omabrowser.org/oma/group/G3MZM9/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q9DAF8-1", "protein_name": "Uncharacterized protein C4orf51 homolog", "gene_name": "", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MTHFLYLTPEILLPFSPLTSTEFELIRRKAQQLWQDETRWSASSMTTYSGSYREKQLDEATCNRLAQRVGQPQFEYKPTPLPGSSAYNTLPGHAGSQEAADGKGRLPDIASPSRDSPLNIKHKVAHQIWGSEVPCPTFLAYRGLRMSPCMQPKKPGFELLMSYRNRGKALLKRLQRQWDYESKLGSSEDSGTDRFSSNTSGSSGRKFK", "length": 208 }, "evidence": [ { "id": "G3MZM9", "url": "https://omabrowser.org/oma/group/G3MZM9/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q9EPV9-1", "protein_name": "Beta-defensin 5", "gene_name": "Defb5", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MKIHYLLFAFLLVLLSPLAGVFSKTINNPVSCCMIGGICRYLCKGNILQNGSCGVTSLNCCKRK", "length": 64 }, "evidence": [ { "id": "G3MZM9", "url": "https://omabrowser.org/oma/group/G3MZM9/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q9EPX4-1", "protein_name": "P2Y purinoceptor 12", "gene_name": "P2ry12", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MEVPGANATSANTTSIPGTSTLCSRDYKITQVLFPLLYTVLFFAGLITNSLAMRIFFQIRSKSNFIIFLKNTVISDLLMILTFPFKILSDAKLGAGHLRTLVCQVTSVTFYFTMYISISFLGLITIDRYLKTTRPFKTSSPSNLLGAKILSVAIWAFMFLLSLPNMILTNRRPKDKDITKCSFLKSEFGLVWHEIVNYICQVIFWINFLIVIVCYSLITKELYRSYVRTRGSAKAPKKRVNIKVFIIIAVFFICFVPFHFARIPYTLSQTRAVFDCNAENTLFYVKESTLWLTSLNACLDPFIYFFLCKSFRNSLMSMLRCSTSGANKKKGQEGGDPSEETPM", "length": 343 }, "evidence": [ { "id": "G3MZM9", "url": "https://omabrowser.org/oma/group/G3MZM9/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "Q9ER80-1", "protein_name": "Receptor-transporting protein 4", "gene_name": "Rtp4", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MLFPDDFSTWEQTFQELMQEEKPGAKWSLHLDKNIVPDGAALGWRQHQQTVLGRFQCSRCCRSWTSAQVMILCHMYPDTLKSQGQARMRIFGQKCQKCFGCQFETPKFSTEIIKRILNNLVNYILQRYYGHRKIALTSNASLGEKVTLDGPHDTRNCEACSLNSHGRCALAHKVKPPRSPSPLPKSSSPSKSCPPPPQTRNTDFGNKTFQDFGNRTFQGCREPPQREIEPPLFLFLSIAAFALFSLFTR", "length": 249 }, "evidence": [ { "id": "G3MZM9", "url": "https://omabrowser.org/oma/group/G3MZM9/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q9FFP9-1", "protein_name": "Serine/threonine-protein kinase SRK2H", "gene_name": "SRK2H", "tax_id": 3702, "organism": "Arabidopsis thaliana", "sequence": { "sequence": "MDKYEVVKDLGAGNFGVARLLRHKETKELVAMKYIERGRKIDENVAREIINHRSLRHPNIIRFKEVILTPTHLAIVMEYASGGELFERICNAGRFSEAEARYFFQQLICGVDYCHSLQICHRDLKLENTLLDGSPAPLLKICDFGYSKSSLLHSRPKSTVGTPAYIAPEVLSRREYDGKHADVWSCGVTLYVMLVGGYPFEDPDDPRNFRKTIQRIMAVQYKIPDYVHISQECRHLLSRIFVTNSAKRITLKEIKKHPWYLKNLPKELTEPAQAAYYKRETPSFSLQSVEDIMKIVGEARNPAPSSNAVKGFDDDEEDVEDEVEEEEEEEEEEEEEEEEEEDEYEKHVKEAHSCQEPPKA", "length": 360 }, "evidence": [ { "id": "G3MZM9", "url": "https://omabrowser.org/oma/group/G3MZM9/", "database": "OMA" } ], "glygen_name": "Arabidopsis", "common_name": "Mouse-ear cress" }, { "uniprot_canonical_ac": "Q9FLZ3-1", "protein_name": "SNF1-related protein kinase catalytic subunit alpha KIN12", "gene_name": "KIN12", "tax_id": 3702, "organism": "Arabidopsis thaliana", "sequence": { "sequence": "MDGSSEKTTNKLVSILPNYRIGKTLGHGSFAKVKLALHVATGHKVAIKILNRSKIKNMGIEIKVQREIKILRFLMHPHIIRQYEVIETPNDIYVVMEYVKSGELFDYIVEKGKLQEDEARHLFQQIISGVEYCHRNMIVHRDLKPENVLLDSQCNIKIVDFGLSNVMHDGHFLKTSCGSPNYAAPEVISGKPYGPDVDIWSCGVILYALLCGTLPFDDENIPNVFEKIKRGMYTLPNHLSHFARDLIPRMLMVDPTMRISITEIRQHPWFNNHLPLYLSIPPLDTIDQAKKIEEEIIQNVVNIGFDRNHVVDSLANRIQNEATVAYHLILDNRNQNSVPNDPFQSKFKEISDGIFNSTLPVQNITSHVGHSFSALYGLKSNVKDDKTWTLGLQSQGSPYDIMTEIFKALQNLKICWKKIGLYNIKCRWVRSFAYYKNHTIEDECAIILPTVIKFEIQLYKVREGKYLLDILRIDGPQFIFFDLCVAFLRELGVL", "length": 494 }, "evidence": [ { "id": "G3MZM9", "url": "https://omabrowser.org/oma/group/G3MZM9/", "database": "OMA" } ], "glygen_name": "Arabidopsis", "common_name": "Mouse-ear cress" }, { "uniprot_canonical_ac": "Q9FVV4-1", "protein_name": "DEAD-box ATP-dependent RNA helicase 55", "gene_name": "RH55", "tax_id": 3702, "organism": "Arabidopsis thaliana", "sequence": { "sequence": "MDSSPPNTIIEEAPPRFSELKPPLSEDIIEALDRSGFEVCTPVQAETIPFLCSHKDVVVDAATGSGKTLAFLLPFIEIIRRSNSYPPKPHQVMGVIISPTRELSAQIHKVARAVRLDFAKCREVEADMNTLEEEGANLLIGTPGRLSDMMKRMEFLDFRNLEILILDEADRLLDMGFQKQVNYIISRLPKQRRTGLFSATQTQAVADLAKAGLRNPYLKCEADQKSSQLVHLLIENKNKKLVVFFMTCACVDYWGLVISKIPSLKSISFFPTHGKMDQKGRDTALASFTEASSGVLLCTDVAARGLDIPGIVYIRSLAIKDREVLEKGLKAFVSFVRAYKEHQCSYIFSWKGLEIGKLAMGYGILSFPYISEVKQDRIGIVGFTPVQGITFEDIKFKNKSREKQRQQNLLARKDKLQQEKRGKRKKSSKEAVDDSNKASRKRKLTGRQRQTIQTAQDEEEMNLRL", "length": 465 }, "evidence": [ { "id": "G3MZM9", "url": "https://omabrowser.org/oma/group/G3MZM9/", "database": "OMA" } ], "glygen_name": "Arabidopsis", "common_name": "Mouse-ear cress" }, { "uniprot_canonical_ac": "Q9JI02-1", "protein_name": "Secretoglobin family 2B member 20", "gene_name": "Scgb2b20", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MKGTLLLLGLLVTGELSFQTTEACLPFFEGYASVLSGSRVWLYQELQAFNATAEEKVALEKIQDCFSEERIRNILLEPKIMEAMVASPECLSYYGLDNIRSILDYISKLLGE", "length": 112 }, "evidence": [ { "id": "G3MZM9", "url": "https://omabrowser.org/oma/group/G3MZM9/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q9JJQ7-1", "protein_name": "X-linked lymphocyte-regulated 4B", "gene_name": "Xlr4b", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MASKIKGRPPKQPKVTPALPSNDSQQLHENNPGNNLALETCGESSSSHGTGGPKPGPSKKTLNERKRKYGVSVNKTVQNIEWNVDHFLKVQHERRQELYKDYSHQFLTLVMMWNIDVDQIKKQAGKLSDILDEQQKLFQQFQSIHMQKIEEFKELCDRHLKNLQAIKCCRRKAIIEEARKLMDYLEKRVTEETVHVNKQEAKDGVQSSLLSLLIS", "length": 215 }, "evidence": [ { "id": "G3MZM9", "url": "https://omabrowser.org/oma/group/G3MZM9/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q9JLV9-1", "protein_name": "Prolactin-2C5", "gene_name": "Prl2c5", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MLPSLIQPCSWILLLLLVNSSLLWKNVASLPMCAMRNDRCFMFFEDTFELAGSLSHNISIEVSELFTEFEKHYSNVPGLRDKSPMRCHTSFLPTPENKEQARHIRYEALLKSGDMILDAWENPLDYLVSELSTIKNVPDIIISKATDIKKKINAVQNGVNALMSTMNGDEENKNPAWFLQSDNEDARIRSSYGMISCLDNDFKKVDIYLNILKCYMLKIDNC", "length": 222 }, "evidence": [ { "id": "G3MZM9", "url": "https://omabrowser.org/oma/group/G3MZM9/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q9LJY9-1", "protein_name": "Cytochrome P450, family 705, subfamily A, polypeptide 18", "gene_name": "CYP705A18", "tax_id": 3702, "organism": "Arabidopsis thaliana", "sequence": { "sequence": "MATLISVDFQHCFMYIILLCLFSLLCYSLFFRKPKGTRVGCDLPPSPPSLPIIGHLHHLLSSLTHKSLQKLSSKYGPFLHLRIFSVPIILVSSASVAYEIFKAHDVNVSSRGAAAIDESLLFGSSSFIYAPYGDYWKFMKKIFATKLLRPQVLENSRGVRAEELKRFYRRILDKARKNENIEISKESAMLMNNILCRMSMGRSFSEENGEAERVRGLVGESYALVKKIFFAATLRRLLEKLRIPLFRKEIMGVSDRFDELLERIIVEHKDKLEKEHQVMDMMDVLLAAYRDKNAEYKITRNHIKSFFVDLFVGGTDTSVQTTQWTMAEIINNPNILQTLRKEIDSVVGKSRLIHETDIPNLPYLQAVVKEGLRLHPPGPLLIRTFQERCEMKGFYIPEKTTLVINAYAVMRDPDSWEDPDEFKPERFLSYSRSGQEDEKEQTLKYLSFGGGRRGCPGVNLGYIFVGTAIGMMVQCFDWKIEGDKVNMEETYGGMNLTMVNPLKCTPVPRTQPFSFTSNLEILSS", "length": 524 }, "evidence": [ { "id": "G3MZM9", "url": "https://omabrowser.org/oma/group/G3MZM9/", "database": "OMA" } ], "glygen_name": "Arabidopsis", "common_name": "Mouse-ear cress" }, { "uniprot_canonical_ac": "Q9LSY1-1", "protein_name": "SKP1-like protein 8", "gene_name": "ASK8", "tax_id": 3702, "organism": "Arabidopsis thaliana", "sequence": { "sequence": "MSTKKIMLKSSEGKTFEIEEETARQCQTIAHMIEAECTDNVILVLKMTSEILEMVIEYCNKHHVDAANPCSDDDLEKWDKEFMEKDKSTIFALTNAANFLNNKSLLHLAGQTVADMIKGNTPKQMREFFNIENDLTPEEEAAIRRENKWAFE", "length": 152 }, "evidence": [ { "id": "G3MZM9", "url": "https://omabrowser.org/oma/group/G3MZM9/", "database": "OMA" } ], "glygen_name": "Arabidopsis", "common_name": "Mouse-ear cress" }, { "uniprot_canonical_ac": "Q9LTG5-1", "protein_name": "Callose synthase 4", "gene_name": "CALS4", "tax_id": 3702, "organism": "Arabidopsis thaliana", "sequence": { "sequence": "MNQPNRGQILQTVFSHFFPVASPDSELVPSSLHEDITPILRVAKDVEDTNPRSLFLQDLDIKSVDDSINILSGHSHALDKANELDPTSSGRDVRQFKNTILQWLEKNNESTLKARQKSSDAHEMQSFYQQYGDEGINDLLNAGAGSSSSQRTKIYQTAVVLYDVLDAVHRKANIKVAAKILESHAEVEAKNKIYVPYNILPLDPDSKNHAMMRDPKIVAVLKAIRYTSDLTWQIGHKINDDEDVLDWLKTMFRFQKDNVSNQREHLILLLANVQMRQTQRQPNLLDDRALDTVMEKLLGNYNKWCNHVGLESSLRFPKDKQQKVVQQRKLLYTGLYLLIWGEAANLRFMPECLCYIYHHMAFELFEMLESKGSKKKYKPKNPTYSGKDEDFLTKVVTPVYKTIAEEAKKSGEGKHSEWRNYDDLNEYFWSKQYLDKLGWPMKANADFFCKTSQQLGLNKSEKKPDLGDGCVGKVNFVEIRTFWHLFRSFDRMWSFYILSLQAMIIIAWNETSESGGAVFHKVLSVFITAAKLNLFQAFLDIALSWKARHSMSTHVRQRYIFKAVAAAVWVLLMPLTYAYSHTSIFIVAILIYLSPNMLPEMLLLIPSIRRTLEKSDFRPVKLIMWWSQPELYIGRGMHESAWSIYKYMMFWIVLLTSKLAFSYYVEQIKPLMGPTKEIMSVPMPGYWLPEFFPHVKNNRGVVITLWSPVILVYFMDTQIWYAIVSTLVGGLYGAFRHIGEIQTLGMLRSRFQSLPGAFNACLIPNENTKEKGIKLAFSRKCHKIPNTNGKEAKQFSQMWNTIINSFREEDLISNRELELLLMSCWAYPDLDFIRWPIFLLASKIPIAVDIAKKRNGKHRELKNILAEDNCMSCAVRECYASIKKLLNTLVTGNSDLMLITTVFTIIDTHIEKDTLLTELNLSVLPDLHGHFVKLTEYVLQNKDKDKIQIVNVLLKILEMVTKDILKEEIKRLHLLLTVKESAMDVPSNLEARRRLTFFSNSLFMEMPGAPKIQNMLSFSALTPYYSEDVLFSTFDLEKENDGVSILFYLQKIFPDEWKNFLERVKCGTEEELDAIDYLKEEIRLWASYRGQTLTKTVRGMMYYQKALELQAFFDLANERELMKGYKSAEASSSGSSLWAECQALADIKFTYVVACQQYSIHKRSGDQRAKDILTLMTTYPSLRVAYIDEVEQTHIYSKGTSENFYYSALVKAAPQTYSTDSSDSGHMLDQVIYQIKLPGPPIIGEGKPENQNNAIIFTRGEALQTIDMNQDYYIEEAFKMRNLLQEFLEKNGGVRYPTILGLREHIFTRSVSCLAWFMSNQEHSFVTIGQRVLANPLKVRFHYGHPDVFDRVFHLTRGGVSKASKVINLSEDIFAGFNSTLREGTVSHHEYIQVGKGRDVGLNQISMFEAKIANGSGEQTLSRDLYRLGHQFDFFRMLSCYFTTVGFYFCSMLTVLTVYVFLYGRLYLVLSGVEKELGNKPMMMEIILASQSFVQIVFLMAMPMIMEIGLERGFYDALFDFVLMQLQLASVFFTFQLGTKFHYYCKTLLHGGAEYRGTGRGFVVFHAKFAENYRFYSRSHFVKATELGILLLVYHIFGPTYIGLFTISIWFMVGTWLFAPFLFNPSGFEWHEIVEDWADWKKWIEYDNGGIGVPPEKSWESWWEKDIEHLQHSGKWGIVVEIFFALRFFIFQYGLVYQLSAFKNKYSSLWVFGASWLLILILLLTVTVLDYARRRLGTEFQLLFRIIKVSLFLAFMAIFITLMTCRLILPQDVFLCMLALIPTGWGLLLIAQSCKPLIQQPGIWSWVMTLAWVYDLVMGSLLFIPIAFMAWFPFISEFQTRMLFNQAFSRGLHISRILSGQRKHRSSKNKD", "length": 1871 }, "evidence": [ { "id": "G3MZM9", "url": "https://omabrowser.org/oma/group/G3MZM9/", "database": "OMA" } ], "glygen_name": "Arabidopsis", "common_name": "Mouse-ear cress" }, { "uniprot_canonical_ac": "Q9LU95-1", "protein_name": "Pyruvate kinase", "gene_name": "", "tax_id": 3702, "organism": "Arabidopsis thaliana", "sequence": { "sequence": "MEMLLGGQATNGALRSKTKIVCTLGPASRSVEMIEKLLKAGMNVARFNFSHGSHSYHQETLDNLRTAMDNTGILCAVMLDTKSPVIRTGFLKEGKPIQLKQGQEITISIDYKIQGDSNTISMSYKKLAEDLKPGDVILCSDGTISLNVLSCDKYLGLVRCRCENSALLGERKNVNLPGIVVDLPTLTEKDKEDIMQWGVPNKIDIIALSFVRKGSDLIQVRKLLGEHSKSIMLMSKVENQEGVMNFDKILENSDAFMVARGDLGMEIPIEKMFLAQKTMINKANAHGKPVVTATQMLESMTVSPRPTRAEATDVANAVLDGTDCVMLSGETAAGAHPETAVLTMSRICKEAEDFIDYDILHKKTLGMVSLPLSPIESLAASAVSTARSVFASAIVVLTRGGYTAELVAKYRPSVPILSVIMPEIAECSDSVAHVARRGLIYRGIIPVVGCSARDSTEEMIRLAIGFAKTKGICKTGDSIVALHKIDGSSIVRIVSVE", "length": 497 }, "evidence": [ { "id": "G3MZM9", "url": "https://omabrowser.org/oma/group/G3MZM9/", "database": "OMA" } ], "glygen_name": "Arabidopsis", "common_name": "Mouse-ear cress" }, { "uniprot_canonical_ac": "Q9LX08-1", "protein_name": "Annexin D6", "gene_name": "ANN6", "tax_id": 3702, "organism": "Arabidopsis thaliana", "sequence": { "sequence": "MASLKIPANIPLPEEDSEQLHKAFKGWGTNEGMIISILAHRNATQRSFIRAVYAANYNKDLLKELDGELSGDFERVVMLWTLDPTERDAYLANESTKLFTKNIWVLVEIACTRPSLEFFKTKQAYHVRYKTSLEEDVAYHTSGNIRKLLVPLVSTFRYDGNADEVNVKLARSEAKTLHKKITEKAYTDEDLIRILTTRSKAQINATLNHFKDKFGSSINKFLKEDSNDDYVQLLKTAIKCLTYPEKYFEKVLRRAINRMGTDEWALTRVVTTRAEVDLERIKEEYLRRNSVPLDRAIANDTSGDYKDMLLALLGHDHA", "length": 318 }, "evidence": [ { "id": "G3MZM9", "url": "https://omabrowser.org/oma/group/G3MZM9/", "database": "OMA" } ], "glygen_name": "Arabidopsis", "common_name": "Mouse-ear cress" }, { "uniprot_canonical_ac": "Q9LXS7-1", "protein_name": "Citrate synthase 1, peroxisomal", "gene_name": "CSY1", "tax_id": 3702, "organism": "Arabidopsis thaliana", "sequence": { "sequence": "MEISERARARLAVLNAHLTVSEPNQVLPAIEPWCTSAHITAAPHGSLKGNLKIVDERTGNEYQVPVSEHGTVKTVDLKKITTGKDDKGLNLYDPGYLNTAPVRSSISYIDGDEGILRYRGYPVEELAEKSTYTEVTYLLIYGNLPSQRQLADWEFAISQNSAVPQGVLDMIQSMPNDVHPVGALVTAMSALSIFYPDANPSLMGLGVYKSKQVRDKQIVRVLGQAPTIAAAAYLRKAGKPPVQPLSNLSYSENFLYMVESMGDRSYKPNPRLARVLDILFILQAEHEMNCSTAAARHLSSSGGDVYTAVSGGVGAIYGPLHGGAVEATINMLSEIGTVENIPEFIESVKNKKRRLSGFGHRIYKNYDPRGKVVKKLADEVFSILGRDPLVEVGDALEKAALSDEYFVKRKLYPNVDFYSGLINRAMGIPSSFTAVSRIAGYLSHWRESLDDPDTKIMRPQQVYTGAGIRHYETVRERTKL", "length": 480 }, "evidence": [ { "id": "G3MZM9", "url": "https://omabrowser.org/oma/group/G3MZM9/", "database": "OMA" } ], "glygen_name": "Arabidopsis", "common_name": "Mouse-ear cress" }, { "uniprot_canonical_ac": "Q9LY06-1", "protein_name": "Glycine/proline-rich protein", "gene_name": "", "tax_id": 3702, "organism": "Arabidopsis thaliana", "sequence": { "sequence": "MITCILKISISSFIVLRIFSFLWFSRWFCCGLCGRFWFRCWFCCWFQFWFRCRFYCRFDTGFDVRFAAGFAADLTIGFTIGFDSGFATFLDVGLDDGFATGLDISFAGGFVTGFATDFDVGFDTGFTIGFDTGFDVGLPAVFSIGFDTGFAVGFAISFTVGFDAGFPTGFFVSLDVGFVADFVIGFATGIGVGFEVDFATDFDTCFATGFAVSFDVGFAGGFSIGFAADFANGFTVGFDGGFDASFFVGLDVGFVVGFVTSFAAGLDVGFAIDFATGFDTGFAFGLAFGFDVGFAAGFAVGFATGFTVVFDVGFASDFFVGLDVGFLTGFATDFDIGFVVDFDIGFATGFVVGFDDGSIVGLVVGLPASLDDGLAIDFVVGLDIGFVTGLFVGLVDGLTTDLDVGLVDGLDDGLDDGLDVDLVVVGFVVDGLAVDLDVGLGVGLTVGFVDGLDVGFDDGLDADTVDGLDVGLDDGLDVDLVDGLDIGLDDGLDVGLDDGLDFGLVDGLDVDLDDGLDVDLVDGLDIGLDDGLDVGLDDGLDFGLVDDGLVVGLFDVFVGTGLSWEIPPPGKLPPDASPLGIGSFGVGPPGASPFIASPSGEGPLSEGLLGIRSFGISPLSIRPLGISPLGISPPNIEPSKADASDADPSNAGPLGISPLSIDPPVAGASDEGPLGKLPPDLSPPGKGSSGEGPLVESPPSEGPLGVDPLGAGSLGISPLGKSPLRIRPLGISPFGKIPSNIDPSSALASDGGPPDEPASAEGSPDVGIFGISPPIIDPPVEGASDGDPPEKLSLDISPLGKGPSGVSLLGAGPPGVGPVIASPPGEGPRDAGPLGAGSLGISPLNIRRLGISPSGISPPNIDLPVAGTSIGGPPDEGASDGGPPDVGPFGISPPIIDPPGESESDGDPAGKLPLDISPLSKGPSCVSPLGVGPVIASPPGEGPLDAGPLGAGSLGISPLNIRRLSISPFGISPSSIDSPVAGTSIGGPPDEGASDGGPPDVGPFGISPPIIDPPGEDASDGDPPGKFPLDISPLGKCPSGVSPLGVGPPGVGPVIASPPGEGPLDAGPLGAGSLGISPLNIRRLGISPFGISPPNIDLPVAGTSIGGPLDEGASDGGPPDVGPFGISPSIIDPPGEGAFDGDPPGKLPLDISPVGKGPSGVSPPGAGPPGDGPVIASPPGESPLDAGPLGAGSLGISPFGISPPNIDWPVAGTSFGGPPGEGASNGGPLVVGPFDMPVVGASDGDALEKLPLDISLPGKGPSDVGPPGAGLPGAAPPGVDLSNVGASDRGASGEGASDGCPPDVGPFDICLLSIDPPVVGASDGGPPDEGASNGGPPDTDSFGGDPLCASPLGIDPPIVDASDGDPFGAGSPDEDPSNENASGEGASGESPPCSDVSCKGPSSAGASIGCSLDNGASTPSSPDTFLSNVFPSDKSSPDAFSPDVAALVTLPSGKDPFDISPPIVALLDVSPLGKTSSDAYSSGISPGIFEKSFPLVKLQTIEYM", "length": 1504 }, "evidence": [ { "id": "G3MZM9", "url": "https://omabrowser.org/oma/group/G3MZM9/", "database": "OMA" } ], "glygen_name": "Arabidopsis", "common_name": "Mouse-ear cress" }, { "uniprot_canonical_ac": "Q9M2S0-1", "protein_name": "Probable mannose-1-phosphate guanylyltransferase 2", "gene_name": "", "tax_id": 3702, "organism": "Arabidopsis thaliana", "sequence": { "sequence": "MKALILVGGFGTRLRPLTLSLPKPLVDFANKPMILHQIEALKAIGVDEVVLAINYEPEQLLVMSKFSNDVEATLGIKITCSQETEPLGTAGPLALARDKLVDGSGQPFFVLNSDVISDYPLEEMIAFHNAHGGEASIMVTKVDEPSKYGVVVMEEATGRVERFVEKPKLFVGNKINAGIYLLNPSVLDRIELRPTSIEKEIFPQIAEAEKLYAMLLPGFWMDIGQPRDYITGLRLYLDSLRKKSPSKLATGPHILGNVLVDETAEIGEGCLIGPNVAIGPGCVVESGVRLSHCTVMRGVHVKRYACISSSIIGWHSTVGQWARVENMSILGKNVYVCDEIYCNGGVVLHNKEIKSDILKPDIVM", "length": 364 }, "evidence": [ { "id": "G3MZM9", "url": "https://omabrowser.org/oma/group/G3MZM9/", "database": "OMA" } ], "glygen_name": "Arabidopsis", "common_name": "Mouse-ear cress" }, { "uniprot_canonical_ac": "Q9NR96-1", "protein_name": "Toll-like receptor 9", "gene_name": "TLR9", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MGFCRSALHPLSLLVQAIMLAMTLALGTLPAFLPCELQPHGLVNCNWLFLKSVPHFSMAAPRGNVTSLSLSSNRIHHLHDSDFAHLPSLRHLNLKWNCPPVGLSPMHFPCHMTIEPSTFLAVPTLEELNLSYNNIMTVPALPKSLISLSLSHTNILMLDSASLAGLHALRFLFMDGNCYYKNPCRQALEVAPGALLGLGNLTHLSLKYNNLTVVPRNLPSSLEYLLLSYNRIVKLAPEDLANLTALRVLDVGGNCRRCDHAPNPCMECPRHFPQLHPDTFSHLSRLEGLVLKDSSLSWLNASWFRGLGNLRVLDLSENFLYKCITKTKAFQGLTQLRKLNLSFNYQKRVSFAHLSLAPSFGSLVALKELDMHGIFFRSLDETTLRPLARLPMLQTLRLQMNFINQAQLGIFRAFPGLRYVDLSDNRISGASELTATMGEADGGEKVWLQPGDLAPAPVDTPSSEDFRPNCSTLNFTLDLSRNNLVTVQPEMFAQLSHLQCLRLSHNCISQAVNGSQFLPLTGLQVLDLSHNKLDLYHEHSFTELPRLEALDLSYNSQPFGMQGVGHNFSFVAHLRTLRHLSLAHNNIHSQVSQQLCSTSLRALDFSGNALGHMWAEGDLYLHFFQGLSGLIWLDLSQNRLHTLLPQTLRNLPKSLQVLRLRDNYLAFFKWWSLHFLPKLEVLDLAGNQLKALTNGSLPAGTRLRRLDVSCNSISFVAPGFFSKAKELRELNLSANALKTVDHSWFGPLASALQILDVSANPLHCACGAAFMDFLLEVQAAVPGLPSRVKCGSPGQLQGLSIFAQDLRLCLDEALSWDCFALSLLAVALGLGVPMLHHLCGWDLWYCFHLCLAWLPWRGRQSGRDEDALPYDAFVVFDKTQSAVADWVYNELRGQLEECRGRWALRLCLEERDWLPGKTLFENLWASVYGSRKTLFVLAHTDRVSGLLRASFLLAQQRLLEDRKDVVVLVILSPDGRRSRYVRLRQRLCRQSVLLWPHQPSGQRSFWAQLGMALTRDNHHFYNRNFCQGPTAE", "length": 1032 }, "evidence": [ { "id": "G3MZM9", "url": "https://omabrowser.org/oma/group/G3MZM9/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "Q9QUG3-1", "protein_name": "Prion-like protein doppel", "gene_name": "Prnd", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MKNRLGTWWVAILCMLLASHLSTVKARGIKHRFKWNRKVLPSSGGQITEARVAENRPGAFIKQGRKLDIDFGAEGNRYYAANYWQFPDGIYYEGCSEANVTKEMLVTSCVNATQAANQAEFSREKQDSKLHQRVLWRLIKEICSAKHCDFWLERGAALRVAVDQPAMVCLLGFVWFIVK", "length": 179 }, "evidence": [ { "id": "G3MZM9", "url": "https://omabrowser.org/oma/group/G3MZM9/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q9SAC9-1", "protein_name": "AP-1 complex subunit mu-1", "gene_name": "AP1M1", "tax_id": 3702, "organism": "Arabidopsis thaliana", "sequence": { "sequence": "MAGAASALFLLDIKGRVLVWRDYRGDVTAAQAERFFTKLIETEGDSQSNDPVAYDNGVTYMFVQHSNIYLMIASRQNCNAASLLFFLHRVVDVFKHYFEELEEESLRDNFVVVYELLDEMMDFGYPQFTEARILSEFIKTDAYRMEVTQRPPMAVTNSVSWRSEGLKFKKNEVFLDVIESVNILVNSNGQIVRSDVVGALKMRTYLSGMPECKLGLNDRILLEAQGRAIKGKAIDLEDIKFHQCVRLARFENDRTISFIPPDGSFDLMTYRLSTQVKPLIWVEAHIERHSRSRVEMLVKARSQFKDRSYATSVEIELPVPTDAYNPDVRTSLGSAAYAPEKDALVWKIQYFYGNKEHTLKADFHLPSIAAEEATPERKAPIRVKFEIPKFIVSGIQVRYLKIIEKSGYQAHPWVRYITMAGEYELRLM", "length": 428 }, "evidence": [ { "id": "G3MZM9", "url": "https://omabrowser.org/oma/group/G3MZM9/", "database": "OMA" } ], "glygen_name": "Arabidopsis", "common_name": "Mouse-ear cress" }, { "uniprot_canonical_ac": "Q9SCN2-1", "protein_name": "Cytochrome P450 71B31", "gene_name": "CYP71B31", "tax_id": 3702, "organism": "Arabidopsis thaliana", "sequence": { "sequence": "MSMFLGLLFLFPLFFILFKNLLPPRKKLPPGPTGLPLIGNLHQLGRLLHSSLHKLSLEHGPVMLVRWGVVPMAVFSSNEAAKEVLKTHDLETCNRPKLVANGLFTHGYKDIGFTQYGEEWREMKKFVGLELFSPKKHKSFRYIREEEGDLLVKKISNYAQTQTLVDLRKSLFSYTASIIFREAFGQNFRECDYINMDKLEELVQETETNVCSLAFTDFFPRGLGWLVDRISGQHSRMNIAFSKLTTFFEDVIDELLKTKQLDDHSDLVTAMLDVINRPRKFGSLKITYDHLIAMMSDVVLAGVNAGTVTMIWTMTELTRHPRVMKKLQEEIRATLGPNKERITEEDLEKVEYLNLVIKESFRLHPPAPLLLPRETMSDIEIQGYHIPKNAHVKINTYAIGRDPKRWTNPEEFNPERFLNTSINYKGQHYELLPFGAGRRNCPGMTLGITILELGLLNILYYFDWSLPSGMTIKDIDMEEDGALNIAKKVPLQLVPTLP", "length": 498 }, "evidence": [ { "id": "G3MZM9", "url": "https://omabrowser.org/oma/group/G3MZM9/", "database": "OMA" } ], "glygen_name": "Arabidopsis", "common_name": "Mouse-ear cress" }, { "uniprot_canonical_ac": "Q9SJ39-1", "protein_name": "Cytochrome P450, family 705, subfamily A, polypeptide 6", "gene_name": "CYP705A6", "tax_id": 3702, "organism": "Arabidopsis thaliana", "sequence": { "sequence": "MAAILSVDFQNCFIFIVLCLFSLFCYSLFFKKPKHPRGCDLPPSPPSLPIIGHLHLLFSPLTHKSLQKLSSKYGHLLHLRIFNVPVILVSSASVAYEIFRAHDVNVSSRGVAAIDESLLFGSSGIITAPYGDYWKFMKKLIATKLLRPQSLESSRGIRGEELTRFYNSLLDKARMTESVEISTEAMKLVNNTLCRMSMGRSFSEENGEAEKIRGLVGESYALTKKMFLASLLRKPLKKLRISLFEKEIMGVSDRLDELLERILVEHEEKLHEEHQGTDMMDVLLAASGDENAEYNITRNHIKSFFVEIFIGATDTSVQTTQWTMAEILNHPNVLERLRKDIDSVVGKTRLIHETDLPNLPYLQAVVKEGLRLHPPGPLLVRTFQERCKIKGFYIPEKTTLVINAYAVMRDPDSWEDPDEFKPERFLRAPPMGGSLDKFIEFS", "length": 442 }, "evidence": [ { "id": "G3MZM9", "url": "https://omabrowser.org/oma/group/G3MZM9/", "database": "OMA" } ], "glygen_name": "Arabidopsis", "common_name": "Mouse-ear cress" }, { "uniprot_canonical_ac": "Q9SMT4-1", "protein_name": "Large ribosomal subunit protein eL13y", "gene_name": "RPL13C", "tax_id": 3702, "organism": "Arabidopsis thaliana", "sequence": { "sequence": "MKHNNVIPNGHFKKKWENYVKTSFNQPAMKTRRRIARQNKAVKIFPRPTAGPIRPVVHAQTLTYNMKVRAGKGFTLEELKAAGIPKKLAPTIGISVDHHRKNRSLEGFQTNVQRLKTYKAKLVIFPRCARTVKVGDSAQQELANATQVQVDHMPIVREMPTMELVKLTSDMKLFNAYDKIRLEGINKRHAGVRAKRAAEAEKEEKK", "length": 206 }, "evidence": [ { "id": "G3MZM9", "url": "https://omabrowser.org/oma/group/G3MZM9/", "database": "OMA" } ], "glygen_name": "Arabidopsis", "common_name": "Mouse-ear cress" }, { "uniprot_canonical_ac": "Q9SSB4-1", "protein_name": "26S proteasome regulatory subunit 7 homolog B", "gene_name": "RPT1B", "tax_id": 3702, "organism": "Arabidopsis thaliana", "sequence": { "sequence": "MIIRDIMEDPENEGPHNMRSDFEPLLSVLRLRDYETGDIIEFDSTEASEEALSDITEFGSTEASEAHFEEPYSARIKKVEKEINELAEKICNLGIKESDTGLAPPNQWDLVSDKQMMQEEQPLLVATCTQIISPNTEDAKYVVDIKKIGKYVVGLGDKASPTDIEAGMRVGVDQKKYQIQIPLPPKIDPSVTMMTVEEKPDATYSDIGGCKEQIEKIREVVELPMLHPEKFVRLGIDPPKGVLCYGPPGSGKTLVARAVANRTGACFIRVVGSELVQKYIGEGARMVRELFQMARSKKACILFFDEIDAIGGARFDDGVGSDNEVQRTMLEILYQLDGFDARGNIKVLMATNRPDILDPALLRPGRLDRKVEFCLPDLEGRTQIFKIHTRTMSCERDIRFELLAGLCPNSTGADIRSVCIEAGMYAIGARRKSVTEKDFLDAVNKVVKGYQKFSATPKYMAYYI", "length": 464 }, "evidence": [ { "id": "G3MZM9", "url": "https://omabrowser.org/oma/group/G3MZM9/", "database": "OMA" } ], "glygen_name": "Arabidopsis", "common_name": "Mouse-ear cress" }, { "uniprot_canonical_ac": "Q9SVM4-1", "protein_name": "Serine hydroxymethyltransferase 5", "gene_name": "SHM5", "tax_id": 3702, "organism": "Arabidopsis thaliana", "sequence": { "sequence": "MEPVYSWGNTHLDFVDPEIYDLIEKEKHRQCRGIELIAAENFTSVAVMEALGSCLTNKYSEGMPGNRYYGGTEFIDEIESLCRSRSLEAFHCNPEKWGVNVQPYSGSPANFAAYTALLQPHDRIMGLDLPSGGHITHGYYSSGGKNISATSIYFENLPYKVDSKTGYIDYDKLEEKAMDFRPKLIICGGTSYPREWDYARFRAVADKVGAFLLCDMAHNSALVAAQEAADPFEYCDVVTTSTHKSLRGPRAGMIFYRKGPKPAKKGQPEGEVYDFDAKINSAVFPALQSGPHNNKIGALAVALKQVMAPSFKVYAKQVKANAACLASYLINKGYTLVTDGTDNHLILWDLRPLGLTGNKVEKVCELCYITLNRNAVFGDTSFLAPGGVRIGTPAMTSRGLVEKDFEKIGEFLHRAVTITLDIQEQYGKVMKDFNKGLVNNKEIDEIKADVEEFTYDFDMPGFFISESRND", "length": 470 }, "evidence": [ { "id": "G3MZM9", "url": "https://omabrowser.org/oma/group/G3MZM9/", "database": "OMA" } ], "glygen_name": "Arabidopsis", "common_name": "Mouse-ear cress" }, { "uniprot_canonical_ac": "Q9SWH4-1", "protein_name": "Syntaxin-42", "gene_name": "SYP42", "tax_id": 3702, "organism": "Arabidopsis thaliana", "sequence": { "sequence": "MATRNRTTVYRKHRDACKSARAPLSLSASDSFGGPVIEMVSGSFSRSNHSSYAPLNSYDPGPSSSDAFTIGMPPAWVDDSEEITFNIQKVRDKMNELAKAHSKALMPTFGDNKGIHREVEMLTHEITDLLRKSEKRLQMLSTRGPSEESNLRKNVQRSLATDLQNLSMELRRKQSTYLKRLQQQKEGQDEVDLEFNVNGKMSRLDEEDELGGMGFDEHQTIKLKEGQHVSAEREREIQQVLGSVNDLAQIMKDLSALVIDQGTIVDRIDYNVQNVSTSVEEGYKQLQKAERTQREGAMVKCATILLVLCLIMIVLLILKNILF", "length": 323 }, "evidence": [ { "id": "G3MZM9", "url": "https://omabrowser.org/oma/group/G3MZM9/", "database": "OMA" } ], "glygen_name": "Arabidopsis", "common_name": "Mouse-ear cress" }, { "uniprot_canonical_ac": "Q9SYN6-1", "protein_name": "SOUL heme-binding family protein", "gene_name": "", "tax_id": 3702, "organism": "Arabidopsis thaliana", "sequence": { "sequence": "MEAALSIFKLSFLLTLLSGGSDLIDSLPPNCNRAECPSYEVVHAGNGYEIHRYNTTVWISTEPIQDISLNEASGNGWNQLSDYMNGNNDYHQRIEIALPYITQVSQNLSTFIVSFFVPKAFQPDPPPGNNLHVQRWDSRYVAVKQISGYVADHKIGKQVAELKASLQGTVWAKAIEKSRETGGVGSAWAYTVAQFSWPFQWSQRVNEIWFPFEMEDEETVSIVTQ", "length": 225 }, "evidence": [ { "id": "G3MZM9", "url": "https://omabrowser.org/oma/group/G3MZM9/", "database": "OMA" } ], "glygen_name": "Arabidopsis", "common_name": "Mouse-ear cress" }, { "uniprot_canonical_ac": "Q9SZB4-1", "protein_name": "Putative DEAD-box ATP-dependent RNA helicase 43", "gene_name": "RH43", "tax_id": 3702, "organism": "Arabidopsis thaliana", "sequence": { "sequence": "MEVDDGYVEYVPVEERLAQMKRKVVEEPGKGMMEHLSDKKKLMSVGELARGITYTEPLSTWWKPPLHVRKMSTKQMDLIRKQWHITVNGEDIPPPIKNFMDMKFPSPLLRMLKDKGIMHPTPIQVQGLPVVLSGRDMIGIAFTGSGKTLVFVLPMIILALQEEIMMPIAAGEGPIALVICPSRELAKQTYDVVEQFVASLVEDGYPRLRSLLCIGGVDMRSQLDVVKKGVHIVVATPGRLKDILAKKKMSLDACRLLTLDEADRLVDLGFEDDIRHVFDHFKSQRQTLLFSATMPAKIQIFATSALVKPVTVNVGRAGAANLDVIQEVEYVKQEAKIVYLLECLQKTTPPVLIFCENKADVDDIHEYLLLKGVEAVAIHGGKDQEDRDYAISLFKAGKKDVLVATDVASKGLDFPDIQHVINYDMPGEIENYVHRIGRTGRCGKTGIATTFINKNQSEITLLDLKHLLQEAKQRIPPVLAELNGPMEETETIANASGVKGCAYCGGLGHRILQCPKFEHQKSVAISSSRKDHFGSDGYRGEV", "length": 542 }, "evidence": [ { "id": "G3MZM9", "url": "https://omabrowser.org/oma/group/G3MZM9/", "database": "OMA" } ], "glygen_name": "Arabidopsis", "common_name": "Mouse-ear cress" }, { "uniprot_canonical_ac": "Q9T0E0-1", "protein_name": "Putative ATPase, plasma membrane-like", "gene_name": "", "tax_id": 3702, "organism": "Arabidopsis thaliana", "sequence": { "sequence": "MATGDSLEDIKIEIDDDLEKIPIEEVFKKLRCSREGLSGAEGKERLKIFGPNKLENKKKEHITLRFFALMFKPLSWVIQAAAIMAMLFANGDGRQLFLGIVCLLIVNTIICYLKEDDAANVVAMARAGLSPKTKVLRDGKWSEQEASILVPGDIVSIKPGDIIPCDARLLEGDTLKVDQSALTGEFGPITKGPGEEVFSGTTCKQGEMEAVVIATGVHTFSGTTAHLVDNRTNKVGHFRKVVTEIENLCVISIAIGISIEVIVMYWIQRRNFSDVINNLLVLVIGGIPLAMPTVLYVIMVTGSLRLYRTGTITQRITAIEDMAAIDVLCSDKTGTLTLNKLSVDKNLIKVYSKDVEKEQVLLLAARASRIENRDGIDAAMVGSLADPKEARAGIREVHFNLVDKRTALTYIDGNGDWHRVSKGTPEQILDLCNARDDLRKSVHSAIRNYAERGLKSFAISWFRNTNCNTVFFFPYQLCSEHKYHIVNKLQERHICGLIGDGVDDVPSLKKADVGIAVANATEAARAASDIVLTEPGLSVIIDAVLASRAILQQMKHYTIYAVSITIRVVFGFMFIALIWKFDFSPFMVLAIALLNEETTKAITMDNVTNPSPTPDSLKLKEIFATGVVYGSYMALITVVFFWAAYRTDIFPRTFHVRDLRGNEAEMMCALYLQVSIMSQALFFVIQSRSWFFVERPGELLFLSFVTVQTIATTLAVYASWETARIEGIGWSWAGVIWLYNIIFFFPLDIMKFGIRYILTGKAQSLFDNMVHLVLNSYAKLSNGIYNHTQADHTYSLLEVSTPPSQDLRGVGWV", "length": 813 }, "evidence": [ { "id": "G3MZM9", "url": "https://omabrowser.org/oma/group/G3MZM9/", "database": "OMA" } ], "glygen_name": "Arabidopsis", "common_name": "Mouse-ear cress" }, { "uniprot_canonical_ac": "Q9T0H7-1", "protein_name": "Histone H2A.8", "gene_name": "", "tax_id": 3702, "organism": "Arabidopsis thaliana", "sequence": { "sequence": "MVCNTNILKDVSTKISAFENVRMIMVEGEMFQVARIHKQLKNRVSAHSSVGATDVVYMTSILEYLTTEVLQLAENTSKDLKVKRITPRHLQLAIRGDEELDTLIKGTIIGGSVIPHIH", "length": 118 }, "evidence": [ { "id": "G3MZM9", "url": "https://omabrowser.org/oma/group/G3MZM9/", "database": "OMA" } ], "glygen_name": "Arabidopsis", "common_name": "Mouse-ear cress" }, { "uniprot_canonical_ac": "Q9VXF6-1", "protein_name": "Calnexin 14D", "gene_name": "Cnx14D", "tax_id": 7227, "organism": "Drosophila melanogaster", "sequence": { "sequence": "MAWKMLFAILLLLSAAKTGYLAPESENSVEDVQIEPGAIYGDEKFAYKSPVIDAEKFYFADHFDDVEASRKRWVLSQAKKNDIADEIAKYDGIWNWESPQRIFWANDLGLVLKSKAKHAAIAAPFRQPFDFKSNKPLVVQYELTLQEGQDCGGSYLKLLSAGKGTEQLNRFNDKTPYTIMFGPDKCGNNLKMHFIFRHVNPLNGNITEKHCKKPNARLGVPFTDKLPHLYQLVVRPDNSFEIRLDHKIIKEGSLLTDFVPPVNPPAEIDDPNDHKPESWDERKKIPDPNAHKPEDWDEDAPPHLPDTDAVMPNGWLEDEPDMIFDPTAIEPEDWNSEIDGEWEAPLVENPVCKKAPGCGKWKAPLIPNPNYKGKWSAPMIENPNNQGKWAPRKIANPDFFEDLKPFQMTPINAVGLELWSMSSDILFDNLIITDDVELARDFAANSFDIKRLYIDRESFGNKVVELARANRAIWGIVIVAIAVPVAITIFCKFGLGPSRVAAAKKAAAAAAKKTDDPQPDDDLGAEEEEKLEKGKKEEEKKEEEEEEEKEENKEEKKEEEKDDEKEMKDCEEEEDDEEKDDEEKTDERAAGDTNKESTPLSASPKKNQKSYLDNNEDEEDTLKNKEPTPKKRKRKALKE", "length": 639 }, "evidence": [ { "id": "G3MZM9", "url": "https://omabrowser.org/oma/group/G3MZM9/", "database": "OMA" } ], "glygen_name": "Fruit fly", "common_name": "Fruit fly" }, { "uniprot_canonical_ac": "Q9W240-1", "protein_name": "K Homology domain-containing protein", "gene_name": "cg3927", "tax_id": 7227, "organism": "Drosophila melanogaster", "sequence": { "sequence": "METPSELTEKQNQDQPTYQPRLNEVAQKFLADLDAERKRLSAEFPLCALLIDESVDRVYSTGRIPGKEPFADVYQQKPMKIIQKVFVPVNKFPKFNFTGKILGPKGNSLRRLQEETHCKIVIKGRNSMRDRNKEEELRSSGDPRYAHLHKDLFLEVSAVAPPAECYARIAYALAEIRKYLIPDDNDDVWHEQQRELMEMNPKSAKKSNGLNMAPYRSNFDKAIGAIRNRAPKYNNQIRRVTENPREVAYMEEVEYDYDEHLMFCSPVVRL", "length": 270 }, "evidence": [ { "id": "G3MZM9", "url": "https://omabrowser.org/oma/group/G3MZM9/", "database": "OMA" } ], "glygen_name": "Fruit fly", "common_name": "Fruit fly" }, { "uniprot_canonical_ac": "Q9W4G6-1", "protein_name": "Uncharacterized protein", "gene_name": "Dmel\\CG2861", "tax_id": 7227, "organism": "Drosophila melanogaster", "sequence": { "sequence": "MDYEIIEFVRRHISHIDISAETRMRYPDPISNNNFDWNSIGLGEQEDAIGQDQQSQALNENANNVSPDVPPSTIAEPTLEPSTIEGNQGQNPRIISSMPDMMPMANSFNPLININQEAGVVINTGINSIDNGLPSTYSEHISQPTNTESTRNMNSSIFDIPSDLDNNSSNESGDEVTQPTAKQSKINANFVCKIESDTNMDKLPTTSNNTNDKPPNNTDSDSDIISISDLIEDLNLDFNQLPITSCDVETHPADTQSNIDANLPYDLISAINMDFVNPANRTYMSAANSTRGTAYKIRKPRTVKRIIKAPSKSNIGKLLREAAKKENAAAGTQRPKKATSTITSSVQNFPNPNNWPACPFPMQNGTMPADEPNDLMPTVSQSLTVPAAQNRPIQTIGKIIKPPVKRTYTKRANKTNNTNIPNKNSTGVIQSNGVAPTIRQGLVEPGGTNILMPWNRQIPMVSVAENPRVQTIDKIIVPPPKRTYKKRVNKTVNTNQSSESAVGDGAPSAPIQSIPKVRKPRGPGKKTAKMVPGQESQQDIPLGVPPNGEAPQTSSQAPVPRVKRAYRKRANNTNNTNILNVNSTGVMESNGGGPTIPNSQQIPNVAVVLNLPIQPIKPKAPRKPRAKKVCNQQPGTDIPFGVSAQGQTAQIKPKPKPRAPRVPKEPKAPKEPKAPKVPKAPRVPKAPRVPKAPRVPKAPRVPKPPKEPKPPKEPKPPKQPKAPRVPKEPKPPKVPKEPKAPRAPRAPRVPKAPKEPKVPKIPKNPRVPKAPRQPKASMNKIQNTVKVPLPIEPVPLETPTYINPINTPVQSTVGEILALGSMPPISPIKFPVLFDEHAAQHTVANSNMPQSSLPTLDIPQLPTRNNKQPSTKSAEDTEILGLGKNKNAMKSDGRIKQGRVSKPSLRFSPSSSSLRPVVRSLSSSSSSSSSWSSCTTCSTCSSCSTCSSSSDSSQSSRSRNRKRRSPKVPIPHKLFESNGEINFQLGQPTRLESPSPPPPVPMQACGTFEEHLTDLTLVRVHAISPLRSPTYDFDFDLPEPMLSEESSSSSSESNDESNVNCQMAPNSQNVSMHFLKVMVFYNCYVLFQQLEKKHQSLFEESSSSSSSESNDETNVNCQMTPNSQNQKKLQSAPIREPSPDQPPEAASRSSNGGTIGPCNLKAFRRDFMISNAENTGFTNPSELNLKKCATKVCTPMERNSGSQLPIQNRFILPNSNKEEGKMNVEPVMPKHKPSRIPIRTKTPIALNLMKEPEDNARKPKNILKPFFSNADVNPCSSTDYEPNFKPCESPLPAKQNDFKLINKDKKSWVSHYQEQESQELKENSFFYAKFNLPNIPKKSFKDSKANAERRCTKTFEDVRKEAQQSRYTKAINKRQNKKAMLESALGNAITEDPTVNCNLADNPNDQVEMPRNPDIVEPTVKPVKFKAFVSASIKPKSSKKRKLMNSASNSKLFKFKIFESEVNKDENEEEDVIPDNLIIPVKRKQNISELLDMQPSTSKAAATITSQPKIAQLKRMPSKLLNEKMKSYAKKRSNDDENKDTKNTGMHMHRYKIPKLSANKPQNTSTTQSPTRGFSRLPGMYQEPNFQNAQHPFSTRGYYPYQRAYPLHRPTSQYHMNQPQPLRLHHSMYVDAEPSFESVFPAPRYQPYNINPSMRHHYSYPGEPSPSTYPMGGIPFQNNNTLYPPMRNDLCYPRGRLNYPVRNLPPMNSQGTYPPNYPQNFLPNYPPSRQFLLSMQRLADINKQIASGSIESVGGFIQMAYAGRKYRTLKDLRERTMLSKDSLRKIFKCMCKIKRPKWRISKFYLYAYWCEISGIPQSSEFGKPLELNAAYRKVISSYAENKFLRMESLMEKTGFGKSKLKRVLKMIGRKRSTKWRLLNYRKPLIHLHRSQDM", "length": 1893 }, "evidence": [ { "id": "G3MZM9", "url": "https://omabrowser.org/oma/group/G3MZM9/", "database": "OMA" } ], "glygen_name": "Fruit fly", "common_name": "Fruit fly" }, { "uniprot_canonical_ac": "Q9W6A5-1", "protein_name": "Green-sensitive opsin-1", "gene_name": "opn1mw1", "tax_id": 7955, "organism": "Danio rerio", "sequence": { "sequence": "MNGTEGSNFYIPMSNRTGLVRSPYDYTQYYLAEPWKFKALAFYMFLLIIFGFPINVLTLVVTAQHKKLRQPLNYILVNLAFAGTIMVIFGFTVSFYCSLVGYMALGPLGCVMEGFFATLGGQVALWSLVVLAIERYIVVCKPMGSFKFSANHAMAGIAFTWFMACSCAVPPLFGWSRYLPEGMQTSCGPDYYTLNPEYNNESYVMYMFSCHFCIPVTTIFFTYGSLVCTVKAAAAQQQESESTQKAEREVTRMVILMVLGFLFAWVPYASFAAWIFFNRGAAFSAQAMAVPAFFSKTSAVFNPIIYVLLNKQFRSCMLNTLFCGKSPLGDDESSSVSTSKTEVSSVSPA", "length": 349 }, "evidence": [ { "id": "G3MZM9", "url": "https://omabrowser.org/oma/group/G3MZM9/", "database": "OMA" } ], "glygen_name": "Zebrafish", "common_name": "Zebrafish" }, { "uniprot_canonical_ac": "Q9XK79-1", "protein_name": "NADH-ubiquinone oxidoreductase chain 4L", "gene_name": "nad4L", "tax_id": 44689, "organism": "Dictyostelium discoideum", "sequence": { "sequence": "MNLIDLILIAIYVIGISGLIFNKNNIINILIISELNLGTLGMLFVLASVELNDILGELSGLYILTFTAAESAIGLAIVVILYSKTGIINIRHLNKLKG", "length": 98 }, "evidence": [ { "id": "G3MZM9", "url": "https://omabrowser.org/oma/group/G3MZM9/", "database": "OMA" } ], "glygen_name": "Cellular slime mold", "common_name": "Social amoeba" }, { "uniprot_canonical_ac": "Q9Y2B0-1", "protein_name": "Protein canopy homolog 2", "gene_name": "CNPY2", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MKGWGWLALLLGALLGTAWARRSQDLHCGACRALVDELEWEIAQVDPKKTIQMGSFRINPDGSQSVVEVPYARSEAHLTELLEEICDRMKEYGEQIDPSTHRKNYVRVVGRNGESSELDLQGIRIDSDISGTLKFACESIVEEYEDELIEFFSREADNVKDKLCSKRTDLCDHALHISHDEL", "length": 182 }, "evidence": [ { "id": "G3MZM9", "url": "https://omabrowser.org/oma/group/G3MZM9/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "Q9Z1X0-1", "protein_name": "C-C motif chemokine 27", "gene_name": "Ccl27", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MMEGLSPASSLPLLLLLLSPAPEAALPLPSSTSCCTQLYRQPLPSRLLRRIVHMELQEADGDCHLQAVVLHLARRSVCVHPQNRSLARWLERQGKRLQGTVPSLNLVLQKKMYSHPQQQN", "length": 120 }, "evidence": [ { "id": "G3MZM9", "url": "https://omabrowser.org/oma/group/G3MZM9/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "S4R2L0-1", "protein_name": "Secretoglobin, family 2B, member 12", "gene_name": "Scgb2b12", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MKGILLLLGLLITGELSFQTTEACVPFFEVYASVLSGSRVWLYHELQSFDATAEEKVALEKIQGCYREERLRNILLEPKIMEAMVASPECRSYYSLDNFRSILDFISNLLGE", "length": 112 }, "evidence": [ { "id": "G3MZM9", "url": "https://omabrowser.org/oma/group/G3MZM9/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "W4VSP8-1", "protein_name": "Vomeronasal type-1 receptor", "gene_name": "Vmn1r10", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MSSFKNVLYFQAGLGVLANMVLLLFYIFIILGHRPKPTDLISCQLTFVHIIMVLTGGDILLTDLFELLNIENDLKCKTIFYISRVMRGLSICTTCLLSVFQAVTISPNTSLMAKFKQKLKKYMACVFLCIWSFNLAFSTNRIFYVGGFTNVSETNQMQVTKSCSLLPMNIIIRGFIFTISTSRDVFLVGVMLTTSVYMVITMFRYHRQCKYLYSISHLRESPEKRATQTIVLLVSFFVVMYWVDFIISFTSDMIWMYDPLILTVQKFMMYAYPTITPLVQISSDNRIIIMLKNLQSKHQQRFFNKDIFFSL", "length": 311 }, "evidence": [ { "id": "G3MZM9", "url": "https://omabrowser.org/oma/group/G3MZM9/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "X1WF74-1", "protein_name": "Uncharacterized protein LOC100334758 precursor", "gene_name": "si:dkey-52p2.5", "tax_id": 7955, "organism": "Danio rerio", "sequence": { "sequence": "MARTSENMIGKVLFVLFLLSGPTSVLTDFHSLQILGTYIKGDTLFPQISFTFMLDDLTVGLYITERDEFIPRDNTTNEDETVSDMLDKIKNELQPLLKGTLIFQNSTESPQLFQIAWHCELLDNNKTGQMILKIAFSGSTTDEVSFYGNNFTCQCQNNMATVPLEYFQMQFKSIYYPVCMTTLGGYLVKRQVQVNRKVQPKVRLIKKVHPKSGGFRLSCLASEFYPYFINLTLLRDGQPVSDHEVTGGDLLPNGDGTYQMRKSLEIRADEREKHKYTCSAKHLDKNLDVDFEFDPSYPVKIVIPVVVLLSLVLVLTAVLIHKCMNKQAASPPEQQEPIEMGGRLRK", "length": 346 }, "evidence": [ { "id": "G3MZM9", "url": "https://omabrowser.org/oma/group/G3MZM9/", "database": "OMA" } ], "glygen_name": "Zebrafish", "common_name": "Zebrafish" } ], "go_annotation": {}, "pro_annotation": [], "site_annotation": [ { "start_pos": 21, "end_pos": 23, "annotation": "n_glycosylation_sequon" }, { "start_pos": 223, "end_pos": 225, "annotation": "n_glycosylation_sequon" }, { "start_pos": 24, "end_pos": 26, "annotation": "n_glycosylation_sequon" }, { "start_pos": 323, "end_pos": 325, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [ { "pdb_id": "AF-G3MZM9-F1", "pdb_chain": "global", "start_pos": 1, "end_pos": 361, "overlap": "1.0", "method": "AlphaFold", "type": "alphafold", "resolution": -1.0, "url": "https://data.glygen.org/ln2downloads/pdb/current/AF-G3MZM9-F1.pdb", "url_external": "https://alphafold.ebi.ac.uk/entry/G3MZM9" } ], "lectin_list": [], "domain_list": [], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "homologset.oma", "label": "OMA Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [ 202 ], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 21, "end_pos": 23 }, { "start_pos": 223, "end_pos": 225 }, { "start_pos": 24, "end_pos": 26 }, { "start_pos": 323, "end_pos": 325 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 1 }, { "field": "total_sites", "count": 1 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 1 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "exact_sites", "count": 1 }, { "field": "exact_o_linked_sites", "count": 1 }, { "field": "fuzzy_sites", "count": 0 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_pos", "start_aa", "end_pos", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": 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"count": 1 }, { "field": "exact_o_linked_sites", "count": 1 }, { "field": "fuzzy_sites", "count": 0 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_pos", "start_aa", "end_pos", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": 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"https://alphafold.ebi.ac.uk/entry/G3MZP7", "database": "AlphaFoldDB", "categories": [] }, { "id": "ENSBTAG00000046771", "url": "https://bgee.org/?page=gene&gene_id=ENSBTAG00000046771", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "cd00063", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd00063", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "100299981", "url": "https://www.ncbi.nlm.nih.gov/gene/100299981", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR003961", "url": "https://www.ebi.ac.uk/interpro/entry/IPR003961", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR013783", "url": "https://www.ebi.ac.uk/interpro/entry/IPR013783", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR036116", "url": "https://www.ebi.ac.uk/interpro/entry/IPR036116", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "bta:100299981", "url": "https://www.genome.jp/dbget-bin/www_bget?bta:100299981", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "PTHR47135", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR47135", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR47135:SF1", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR47135:SF1", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00041", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00041", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "G3MZP7", "url": "https://www.uniprot.org/uniprotkb/G3MZP7", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "G3MZP7-1", "url": "https://www.uniprot.org/uniprotkb/G3MZP7-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MAGARVKFLSVVGFSLICLKMVASTKTAPEIPTIDQAYSKISNSITVEWATVPGATSYLLTAKDGNTVVETMVANSPGTVTGLKAATLYQITIRSISPAGRSQASPPKQAKTVLAAPILQVSSPSSDSILVQWEAVYMAIGFSVSIMQANGLGRIWKENTTNTSLTFTSLDSGTLYTIKAYAWNANGTPGDDSTCNQRTSPGTPANIQVSFDSGALKASVSWAPTEGAFNYTVMALSDSSRLSCSTTFSSCIIYSLQCGTKYLISVSASNDAGSSRSTSAVTLKTVACAPGRVAIQEDPPGHLSVAWSNVDLGDYYVAFVKSDDGLEVHCNTSLTQCNFLSECGFTYFISVFAYNKAGQSPLGDVFNYTTAPCCPSDINPVLVSSDRVEIVWSPVRGAELYETKAVDGFNVVECNDTAPACTLSALECDTKYNITVYSFSEVRGSNTSCTSQFITTAPCSPEIKNISKDDFSMINVRWQSTNDEATYTVTAQGEKGLHQCSSTGESCILGGLPCGSVFSVTAVAETPAGRSLPSYSVPLETAPCCSASLTVTQVTQSVINVSWTIGTGALTYVTVLQSHTGQSKCHTHQNHCLLGCITCGINYTVAVKAVSATGLTADCAYQSYSSSACCPLGVKLYRLGPNGIRIHWQASRGSANYSTDLYGSKGIFTCAPSAGLSFCDVTEIPCGDVYTVMVSPVAETGLKLTFCPKKIYSVTCSGSTLGMVIYRGKRNVE", "length": 733, "header": "tr|G3MZP7-1|G3MZP7_BOVIN Isoform 1 of Fibronectin type III domain containing 7 OS=Bos taurus OX=9913 GN=FNDC7 PE=4 SV=3 CANONICAL=G3MZP7-1" }, "isoforms": [ { "isoform_ac": "G3MZP7-1", "url": "https://www.uniprot.org/uniprotkb/G3MZP7/entry", "sequence": { "sequence": "MAGARVKFLSVVGFSLICLKMVASTKTAPEIPTIDQAYSKISNSITVEWATVPGATSYLLTAKDGNTVVETMVANSPGTVTGLKAATLYQITIRSISPAGRSQASPPKQAKTVLAAPILQVSSPSSDSILVQWEAVYMAIGFSVSIMQANGLGRIWKENTTNTSLTFTSLDSGTLYTIKAYAWNANGTPGDDSTCNQRTSPGTPANIQVSFDSGALKASVSWAPTEGAFNYTVMALSDSSRLSCSTTFSSCIIYSLQCGTKYLISVSASNDAGSSRSTSAVTLKTVACAPGRVAIQEDPPGHLSVAWSNVDLGDYYVAFVKSDDGLEVHCNTSLTQCNFLSECGFTYFISVFAYNKAGQSPLGDVFNYTTAPCCPSDINPVLVSSDRVEIVWSPVRGAELYETKAVDGFNVVECNDTAPACTLSALECDTKYNITVYSFSEVRGSNTSCTSQFITTAPCSPEIKNISKDDFSMINVRWQSTNDEATYTVTAQGEKGLHQCSSTGESCILGGLPCGSVFSVTAVAETPAGRSLPSYSVPLETAPCCSASLTVTQVTQSVINVSWTIGTGALTYVTVLQSHTGQSKCHTHQNHCLLGCITCGINYTVAVKAVSATGLTADCAYQSYSSSACCPLGVKLYRLGPNGIRIHWQASRGSANYSTDLYGSKGIFTCAPSAGLSFCDVTEIPCGDVYTVMVSPVAETGLKLTFCPKKIYSVTCSGSTLGMVIYRGKRNVE", "length": 733, "header": "tr|G3MZP7-1|G3MZP7_BOVIN Isoform 1 of Fibronectin type III domain containing 7 OS=Bos taurus OX=9913 GN=FNDC7 PE=4 SV=3 CANONICAL=G3MZP7-1" }, "locus": { "chromosome": "3", "start_pos": 34658968, "end_pos": 34627081, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000063383.3", "url": "https://www.ensembl.org/id/ENSBTAT00000063383.3" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000055049.3", "url": "https://www.ensembl.org/id/ENSBTAP00000055049.3" } ] } } ], "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "other", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 188, "start_aa": "Thr", "end_pos": 188, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr188", "evidence": [ { "id": "", "database": "GlyGen", "url": "https://data.glygen.org/" } ], "filter_code": "000000000000000010000.00000000001000.0.01000" }, { "glytoucan_ac": "", "type": "O-linked", "subtype": "other", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 203, "start_aa": "Thr", "end_pos": 203, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr203", "evidence": [ { "id": "", "database": "GlyGen", "url": "https://data.glygen.org/" } ], "filter_code": "000000000000000010000.00000000001000.0.01000" } ], "phosphorylation": [], "glycation": [], "keywords": [ "glycoprotein", "glycoprotein_predicted" ], "publication": [], "pathway": [ { "id": "bta:100299981", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?bta:100299981", "resource": "KEGG Pathway" } ], "orthologs": [], "go_annotation": {}, "pro_annotation": [], "site_annotation": [ { "start_pos": 159, "end_pos": 161, "annotation": "n_glycosylation_sequon" }, { "start_pos": 162, "end_pos": 164, "annotation": "n_glycosylation_sequon" }, { "start_pos": 186, "end_pos": 188, "annotation": "n_glycosylation_sequon" }, { "start_pos": 230, "end_pos": 232, "annotation": "n_glycosylation_sequon" }, { "start_pos": 331, "end_pos": 333, "annotation": "n_glycosylation_sequon" }, { "start_pos": 367, "end_pos": 369, "annotation": "n_glycosylation_sequon" }, { "start_pos": 415, "end_pos": 417, "annotation": "n_glycosylation_sequon" }, { "start_pos": 433, "end_pos": 435, "annotation": "n_glycosylation_sequon" }, { "start_pos": 446, "end_pos": 448, "annotation": "n_glycosylation_sequon" }, { "start_pos": 465, "end_pos": 467, "annotation": "n_glycosylation_sequon" }, { "start_pos": 560, "end_pos": 562, "annotation": "n_glycosylation_sequon" }, { "start_pos": 602, "end_pos": 604, "annotation": "n_glycosylation_sequon" }, { "start_pos": 656, "end_pos": 658, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [ { "pdb_id": "AF-G3MZP7-F1", "pdb_chain": "global", "start_pos": 1, "end_pos": 733, "overlap": "1.0", "method": "AlphaFold", "type": "alphafold", "resolution": -1.0, "url": "https://data.glygen.org/ln2downloads/pdb/current/AF-G3MZP7-F1.pdb", "url_external": "https://alphafold.ebi.ac.uk/entry/G3MZP7" } ], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "G3MZP7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3MZP7" }, { "id": "PS50853", "database": "PROSITE", "url": "https://prosite.expasy.org/PS50853" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "Fibronectin type-III", "eco_id": "ECO_0000259", "start_pos": 28, "end_pos": 112, "start_aa": "Ala", "end_aa": "Thr", "glycosite_overlap": [] } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [ 188, 203 ], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 159, "end_pos": 161 }, { "start_pos": 162, "end_pos": 164 }, { "start_pos": 186, "end_pos": 188 }, { "start_pos": 230, "end_pos": 232 }, { "start_pos": 331, "end_pos": 333 }, { "start_pos": 367, "end_pos": 369 }, { "start_pos": 415, "end_pos": 417 }, { "start_pos": 433, "end_pos": 435 }, { "start_pos": 446, "end_pos": 448 }, { "start_pos": 465, "end_pos": 467 }, { "start_pos": 560, "end_pos": 562 }, { "start_pos": 602, "end_pos": 604 }, { "start_pos": 656, "end_pos": 658 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 2 }, { "field": "total_sites", "count": 2 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 2 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "exact_sites", "count": 2 }, { "field": "exact_o_linked_sites", "count": 2 }, { "field": "fuzzy_sites", "count": 0 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_pos", "start_aa", "end_pos", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 2 }, { "field": "total_sites", "count": 2 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 2 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "exact_sites", "count": 2 }, { "field": "exact_o_linked_sites", "count": 2 }, { "field": "fuzzy_sites", "count": 0 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_pos", "start_aa", "end_pos", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ], "tool_support": { "graph_view": "yes" } }, { "uniprot_canonical_ac": "G3MZQ5-1", "uniprot_ac": "G3MZQ5", "uniprot_id": "G3MZQ5_BOVIN", "mass": { "chemical_mass": 65851.0, "monoisotopic_mass": 65851.0 }, "refseq": { "ac": "XP_003587024", "name": "ubiquilin-like protein", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_003587024" }, "gene_names": [ { "name": "UBQLNL", "type": "recommended", "evidence": [ { "id": "G3MZQ5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3MZQ5" } ] }, { "name": "UBQLNL", "type": "synonym", "evidence": [ { "id": "XP_003587024", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_003587024" } ] } ], "protein_names": [ { "name": "Ubiquilin-like protein", "type": "recommended", "evidence": [ { "id": "G3MZQ5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3MZQ5/entry#names_and_taxonomy" } ] }, { "name": "ubiquilin-like protein", "type": "synonym", "evidence": [ { "id": "XP_003587024", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_003587024" } ] } ], "function": [], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Bos taurus", "taxid": 9913, "evidence": [ { "database": "UniProtKB", "id": "G3MZQ5", "url": "https://www.uniprot.org/uniprotkb/G3MZQ5" } ], "common_name": "Bovine", "glygen_name": "Bovine", "reference_species": "Bos taurus [9913]" } ], "gene": [ { "name": "UBQLNL", "url": "https://www.uniprot.org/uniprotkb/G3MZQ5", "locus": { "chromosome": "15", "start_pos": 48054616, "end_pos": 48052811, "strand": "-", "evidence": [ { "database": "Ensembl Gene", "id": "ENSBTAG00000005671", "url": "https://www.ensembl.org/id/ENSBTAG00000005671" } ] } } ], "crossref": [ { "id": "G3MZQ5", "url": "https://alphafold.ebi.ac.uk/entry/G3MZQ5", "database": "AlphaFoldDB", "categories": [] }, { "id": "ENSBTAG00000005671", "url": "https://bgee.org/?page=gene&gene_id=ENSBTAG00000005671", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "cd01808", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd01808", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "515028", "url": "https://www.ncbi.nlm.nih.gov/gene/515028", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR000626", "url": "https://www.ebi.ac.uk/interpro/entry/IPR000626", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR006636", "url": "https://www.ebi.ac.uk/interpro/entry/IPR006636", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR009060", "url": "https://www.ebi.ac.uk/interpro/entry/IPR009060", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR015496", "url": "https://www.ebi.ac.uk/interpro/entry/IPR015496", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR015940", "url": "https://www.ebi.ac.uk/interpro/entry/IPR015940", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR029071", "url": "https://www.ebi.ac.uk/interpro/entry/IPR029071", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "bta:515028", "url": "https://www.genome.jp/dbget-bin/www_bget?bta:515028", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "LSAHFKC", "url": "https://omabrowser.org/oma/group/LSAHFKC/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "G3MZQ5", "url": "https://www.orthodb.org/?gene=G3MZQ5", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR10677", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR10677", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR10677:SF9", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR10677:SF9", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00240", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00240", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF23195", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF23195", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "XP_003587024", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_003587024", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "G3MZQ5", "url": "https://www.uniprot.org/uniprotkb/G3MZQ5", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "G3MZQ5-1", "url": "https://www.uniprot.org/uniprotkb/G3MZQ5-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MPHVIARTPRMAQCGHHSGLPAEKKISPVVTRVIVKTPGKQEDFVIANDTSVRQFKEKLSAHFKCQMDQLVLVFMGRLLKDHDVLSQRGILDGHTIHVVIKSKNGSRSLAHPCHQDKNTKGNSSGVYQSVGVGYTPVESALSEDAPKVHTQDVKVGSPEHIAQILENPSIQQLLSNTDFMRQFISEHLDIQQLMQQNPEVSHFLDNSEILWQTLELARNLAVIQEIMQIQQPAQNLESPPNPQSYVGLETVPGWDSASGQSSADFSDQMLNSTQDPFGGNIFTALLGGQVPEQVQFSLPSPPPSQEQQEHLPQPPTARVIYANSRGVSSITSVNSTLNMANHTSRASTSNSTNGQSHASAVEQPTGIPALPSRELNQLPQAEDKDATISLDSSNQKLDDLQQSNEQTSSQIQGNMMQLLLNNPSLADQMMLFMSVPQLSEQWRQQLPAFLQQTQFSDMLLALANPKASQAILQIEQSLQLLATEAPVLLPCVAPYLWGLGWLPAPSCSYPDTVPWTWDVSNMAEPKGPESCPKSGAVLQRLQSLAGDPSHPLQAPETRFSKQMEYLQAMGFANHHANLQALIATEGDTSAAIQKLRRSQGS", "length": 601, "header": "tr|G3MZQ5-1|G3MZQ5_BOVIN Isoform 1 of Ubiquilin-like protein OS=Bos taurus OX=9913 GN=UBQLNL PE=4 SV=1 CANONICAL=G3MZQ5-1" }, "isoforms": [ { "isoform_ac": "G3MZQ5-1", "url": "https://www.uniprot.org/uniprotkb/G3MZQ5/entry", "sequence": { "sequence": "MPHVIARTPRMAQCGHHSGLPAEKKISPVVTRVIVKTPGKQEDFVIANDTSVRQFKEKLSAHFKCQMDQLVLVFMGRLLKDHDVLSQRGILDGHTIHVVIKSKNGSRSLAHPCHQDKNTKGNSSGVYQSVGVGYTPVESALSEDAPKVHTQDVKVGSPEHIAQILENPSIQQLLSNTDFMRQFISEHLDIQQLMQQNPEVSHFLDNSEILWQTLELARNLAVIQEIMQIQQPAQNLESPPNPQSYVGLETVPGWDSASGQSSADFSDQMLNSTQDPFGGNIFTALLGGQVPEQVQFSLPSPPPSQEQQEHLPQPPTARVIYANSRGVSSITSVNSTLNMANHTSRASTSNSTNGQSHASAVEQPTGIPALPSRELNQLPQAEDKDATISLDSSNQKLDDLQQSNEQTSSQIQGNMMQLLLNNPSLADQMMLFMSVPQLSEQWRQQLPAFLQQTQFSDMLLALANPKASQAILQIEQSLQLLATEAPVLLPCVAPYLWGLGWLPAPSCSYPDTVPWTWDVSNMAEPKGPESCPKSGAVLQRLQSLAGDPSHPLQAPETRFSKQMEYLQAMGFANHHANLQALIATEGDTSAAIQKLRRSQGS", "length": 601, "header": "tr|G3MZQ5-1|G3MZQ5_BOVIN Isoform 1 of Ubiquilin-like protein OS=Bos taurus OX=9913 GN=UBQLNL PE=4 SV=1 CANONICAL=G3MZQ5-1" }, "locus": { "chromosome": "15", "start_pos": 48054613, "end_pos": 48052811, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000007451.7", "url": "https://www.ensembl.org/id/ENSBTAT00000007451.7" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000055058.1", "url": "https://www.ensembl.org/id/ENSBTAP00000055058.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [ { "id": "bta:515028", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?bta:515028", "resource": "KEGG Pathway" } ], "orthologs": [ { "uniprot_canonical_ac": "Q14DL0-1", "protein_name": "Ubiquilin-like protein", "gene_name": "Ubqlnl", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MPRIISRSPKMPQSRYTAGVPADGKISPGVIRVIVKTPGNQIIFTVADDTLVRQFKEILSAHFKCQMEQLVLVFMGRLLKDHDTLSQRGITDGHIIHVVIKSKHGPRSLAHSFRNLVTNNPCHQDRNPKGNSSMVCQSAGMNETKVESSLLMEPEAPKVGTESPEVGSLEHIAQVLENLCVQSLLSNMDFVHQMPPEQPYMEELIQQNPEVSHLLDNSEILCQTLELVRHLAIIQEIMQIQQPAQNPEYPPNSQPFLGLETVPNGNNHLGQSYVNNNDHMLNGVPDLLEGNCFTALLDEQVLEQVQTPSLSQPLPQEQWDQLSSSQVIYANSCGLSSITPTNATPNHTNNVSRENPAIVATQGQSNVCAVQQPAEIPVLPTISINQKPQVDKDTTITLGISDQWLEEDLQQSDDQTSSQITGGMIQLLRNHPQMAAQMLLLMNTSQLNEQWRQETPTPLQSSQLHDLLLALANPKTSQALLQIEHGLQLLATEAPALLPYIEPYLWGLGWLIPSICSYPDIVPWTWNVQDMAEPQCPESCHKSETVLQKVQPPSGDPSHSLQAPEVRFSKEMECLQAMGFVNYNANLQALIATDGDTNAAIYKLKSSQGF", "length": 610 }, "evidence": [ { "id": "G3MZQ5", "url": "https://omabrowser.org/oma/group/G3MZQ5/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q5XIP4-1", "protein_name": "Ubiquilin-like protein", "gene_name": "Ubqlnl", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": 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"MWHAISRTSRMSQSGCPSGLLADKNISSSATRVIVKTAGNQKDFMVADDISVRQFKEMLLAHFQCQMDQLVLVFMGCLLKDHDTLSQRGIMDGHTIYLVIKSKQGSRSLAHSFRDLPTNDPCHRDRNTKGNSSRVHQPTGMNQAPVELAHFVGSDAPKVHTQNLEVSHPECKAQMLENPSIQRLLSNMEFMWQFISEHLDTQQLMQQNPEVSRLLLDNSEILLQTLELARNLAMIQEIMQIQQPSQNLEYPLNPQPYLGLETMPGGNNALGQNYADINDQMLNSMQDPFGGNPFTALLAGQVLEQVQSSPPPPPPSQEQQDQLTQHPATRVIYNSSGGFSSNTSANDTLNKVNHTSKANTAMISTKGQSHICATRQPAWIPALPSIELTQQLQEEYKDATVSLSSSRQTLKGDLQLSDEQSSSQITGGMMQLLMNNPYLAAQIMLFTSMPQLSEQWRQQLPTFLQQTQISDLLSA", "length": 475 }, "evidence": [ { "id": "G3MZQ5", "url": "https://omabrowser.org/oma/group/G3MZQ5/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" } ], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 1, "go_terms": [ { "name": "cytosol", "id": "GO:0005829", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005829", "evidence": [ { "database": "UniProtKB", "id": "G3MZQ5", "url": "https://www.uniprot.org/uniprotkb/G3MZQ5" } ], "pmid": "" } ] }, { "name": "Molecular Function", "total": 1, "go_terms": [ { "name": "polyubiquitin modification-dependent protein binding", "id": "GO:0031593", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0031593", "evidence": [ { "database": "UniProtKB", "id": "G3MZQ5", "url": "https://www.uniprot.org/uniprotkb/G3MZQ5" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 1, "go_terms": [ { "name": "ubiquitin-dependent protein catabolic process", "id": "GO:0006511", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006511", "evidence": [ { "database": "UniProtKB", "id": "G3MZQ5", "url": "https://www.uniprot.org/uniprotkb/G3MZQ5" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 104, "end_pos": 106, "annotation": "n_glycosylation_sequon" }, { "start_pos": 122, "end_pos": 124, "annotation": "n_glycosylation_sequon" }, { "start_pos": 271, "end_pos": 273, "annotation": "n_glycosylation_sequon" }, { "start_pos": 334, "end_pos": 336, "annotation": "n_glycosylation_sequon" }, { "start_pos": 341, "end_pos": 343, "annotation": "n_glycosylation_sequon" }, { "start_pos": 350, "end_pos": 352, "annotation": "n_glycosylation_sequon" }, { "start_pos": 48, "end_pos": 50, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [ { "pdb_id": "AF-G3MZQ5-F1", "pdb_chain": "global", "start_pos": 1, "end_pos": 601, "overlap": "1.0", "method": "AlphaFold", "type": "alphafold", "resolution": -1.0, "url": "https://data.glygen.org/ln2downloads/pdb/current/AF-G3MZQ5-F1.pdb", "url_external": "https://alphafold.ebi.ac.uk/entry/G3MZQ5" } ], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "G3MZQ5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3MZQ5" }, { "id": "PS50030", "database": "PROSITE", "url": "https://prosite.expasy.org/PS50030" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "UBA", "eco_id": "ECO_0000259", "start_pos": 553, "end_pos": 598, "start_aa": "Gln", "end_aa": "Ser", "glycosite_overlap": [] }, { "evidence": [ { "id": "G3MZQ5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3MZQ5" }, { "id": "PS50053", "database": "PROSITE", "url": "https://prosite.expasy.org/PS50053" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "Ubiquitin-like", "eco_id": "ECO_0000259", "start_pos": 31, "end_pos": 105, "start_aa": "Thr", "end_aa": "Gly", "glycosite_overlap": [] } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "homologset.oma", "label": "OMA Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 104, "end_pos": 106 }, { "start_pos": 122, "end_pos": 124 }, { "start_pos": 271, "end_pos": 273 }, { "start_pos": 334, "end_pos": 336 }, { "start_pos": 341, "end_pos": 343 }, { "start_pos": 350, "end_pos": 352 }, { "start_pos": 48, "end_pos": 50 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ], "tool_support": { "graph_view": "yes" } }, { "uniprot_canonical_ac": "G3MZQ7-1", "uniprot_ac": "G3MZQ7", "uniprot_id": "G3MZQ7_BOVIN", "mass": { "chemical_mass": 42183.0, "monoisotopic_mass": 42183.0 }, "refseq": {}, "gene_names": [ { "name": "LOC785868", "type": "recommended", "evidence": [ { "id": "G3MZQ7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3MZQ7" } ] } ], "protein_names": [ { "name": "3'-5' exoribonuclease 1", "type": "recommended", "evidence": [ { "id": "G3MZQ7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3MZQ7/entry#names_and_taxonomy" } ] }, { "name": "3.1.13.1", "type": "synonym", "evidence": [ { "id": "G3MZQ7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3MZQ7/entry#names_and_taxonomy" } ] }, { "name": "Histone mRNA 3'-exonuclease 1", "type": "synonym", "evidence": [ { "id": "G3MZQ7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3MZQ7/entry#names_and_taxonomy" } ] } ], "function": [], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Bos taurus", "taxid": 9913, "evidence": [ { "database": "UniProtKB", "id": "G3MZQ7", "url": "https://www.uniprot.org/uniprotkb/G3MZQ7" } ], "common_name": "Bovine", "glygen_name": "Bovine", "reference_species": "Bos taurus [9913]" } ], "gene": [ { "name": "LOC785868", "url": "https://www.uniprot.org/uniprotkb/G3MZQ7", "locus": {} } ], "crossref": [ { "id": "G3MZQ7", "url": "https://alphafold.ebi.ac.uk/entry/G3MZQ7", "database": "AlphaFoldDB", "categories": [] }, { "id": "cd06133", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd06133", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "IPR003034", "url": "https://www.ebi.ac.uk/interpro/entry/IPR003034", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR012337", "url": "https://www.ebi.ac.uk/interpro/entry/IPR012337", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR013520", "url": "https://www.ebi.ac.uk/interpro/entry/IPR013520", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR036361", "url": "https://www.ebi.ac.uk/interpro/entry/IPR036361", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR036397", "url": "https://www.ebi.ac.uk/interpro/entry/IPR036397", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR047201", "url": "https://www.ebi.ac.uk/interpro/entry/IPR047201", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR051274", "url": "https://www.ebi.ac.uk/interpro/entry/IPR051274", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "PTHR23044", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR23044", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR23044:SF61", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR23044:SF61", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00929", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00929", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF02037", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF02037", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "G3MZQ7", "url": "https://www.uniprot.org/uniprotkb/G3MZQ7", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "G3MZQ7-1", "url": "https://www.uniprot.org/uniprotkb/G3MZQ7-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MEDEQTLQPGDKAMAPARWASPGSECGDEAQRPNPEKKQWCRLDGQETKASTLITSSANDFSDPVYKEIAIMNGCINRMSKEELRAKLSEFKLETTGVKDVLKKRLKNYYKKLKLMLKESNCADSYYDYICIIDFEATCEEGNPPEFIHEIIEFSVVLLNTHTLEIEDTFQQYVRPEINTQLSDFCINLTGITQDQVDKADTFPQVLKKVIDWMKLKELGTKYKYSILTDGSWDMSKFLNIQCQLSRLKYPPFAKKWISIQKSYGNFYKVPRSQIKLTIMLEKLGMDYDGWPHSGLDDSKNVARIAVRMLQDGCELRVNEKIGLGQLMSVSSSLPIEGTPAPQMPHSRKQQHFCPFACGSFTVTGAATKR", "length": 370, "header": "tr|G3MZQ7-1|G3MZQ7_BOVIN Isoform 1 of 3'-5' exoribonuclease 1 OS=Bos taurus OX=9913 GN=LOC785868 PE=4 SV=4 CANONICAL=G3MZQ7-1" }, "isoforms": [ { "isoform_ac": "G3MZQ7-1", "url": "https://www.uniprot.org/uniprotkb/G3MZQ7/entry", "sequence": { "sequence": 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"MKQRFTDRRGEQSPTDQATLSLASPESTEESVQARRTGPVKREQLSPPPGPAIPHAENVYFSGKGRGMLSWSSSPSSQSSSEYQSYSQYQSCHSCTYGDQDAAQQSMCAFYTHVKTVQGVAVAWETDSGFEPVTRQPRIREAEFIRRQRRKGSSFEMASNTDLRWELEASKNNTSSEPEDAELLAPLECCLQELRDTPDWLVTTNCGLRCVACCRVFPTLEALLEHAQYGIQEGFSCQIFFEEMLERRRARDQGQEQEPEEEQESASDSSKGPRPRVTVPSSQSQSQKH", "length": 289, "header": "tr|G3MZZ7-1|G3MZZ7_BOVIN Isoform 1 of Family with sequence similarity 170 member B OS=Bos taurus OX=9913 GN=FAM170B PE=4 SV=2 CANONICAL=G3MZZ7-1" }, "isoforms": [ { "isoform_ac": "G3MZZ7-1", "url": "https://www.uniprot.org/uniprotkb/G3MZZ7/entry", "sequence": { "sequence": "MKQRFTDRRGEQSPTDQATLSLASPESTEESVQARRTGPVKREQLSPPPGPAIPHAENVYFSGKGRGMLSWSSSPSSQSSSEYQSYSQYQSCHSCTYGDQDAAQQSMCAFYTHVKTVQGVAVAWETDSGFEPVTRQPRIREAEFIRRQRRKGSSFEMASNTDLRWELEASKNNTSSEPEDAELLAPLECCLQELRDTPDWLVTTNCGLRCVACCRVFPTLEALLEHAQYGIQEGFSCQIFFEEMLERRRARDQGQEQEPEEEQESASDSSKGPRPRVTVPSSQSQSQKH", "length": 289, "header": "tr|G3MZZ7-1|G3MZZ7_BOVIN Isoform 1 of Family with sequence similarity 170 member B OS=Bos taurus OX=9913 GN=FAM170B PE=4 SV=2 CANONICAL=G3MZZ7-1" }, "locus": { "chromosome": "28", "start_pos": 43397864, "end_pos": 43394123, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000064816.3", "url": "https://www.ensembl.org/id/ENSBTAT00000064816.3" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000055151.2", "url": "https://www.ensembl.org/id/ENSBTAP00000055151.2" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [ { "id": "bta:615859", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?bta:615859", "resource": "KEGG Pathway" } ], "orthologs": [ { "uniprot_canonical_ac": "A6NMN3-1", "protein_name": "Protein FAM170B", "gene_name": "FAM170B", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MKCYFTDHRGEQSPTDGTTLSLTSPESTEESVEVFWPGTIQREGSSPRPGPAIPREEGLYFAARDRGMRDWSSSPSSESSEYQSYSQYQSCCSCMCDEDNAAPQSVCAFYTHVQTVRGVAVAWETEAGFEPVTRKPRIHEAQFIKRQRWNGSSFEMASNTDMRWDLEACKSNCSPEPEDIDLLECCLQELREPPDWLVTTNYGVRCVACCRVLPSLDALLEHAQHGIREGFSCQIFFEEMLERRRAQGQAHDQQLEEEQSPSDNSECSRPQGEVLSAQQQEKQ", "length": 283 }, "evidence": [ { "id": "G3MZZ7", "url": "https://omabrowser.org/oma/group/G3MZZ7/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "D3ZLX4-1", "protein_name": "Family with sequence similarity 170, member B", "gene_name": "Fam170b", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": 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"MKHHLIEHRGEQTPGTAVGMASPDAAEESTGVCWPGGAMRRNESSPRPGPAFLPDDDIYLAARAQGVLGWSSSPSSQSSSEYQSYSQYQSWDSSKSEEQQETPPESVCALYTHVQTVRGVAVAWETDDGFEPVTRKPLIREAEFIKRQRRKGSSFEMASNTDLRWELEDCKHYCPQTEDPVDCCMQELRAPPDWLVTTNHGLRCVACCRVFPTLEALLDHAQHGIQDGFSCQIFFEEMLERKRTRDQKQDQQPVEEEQSLSDSSECTRLLTKVLPWQQQPQQQPQEQQKQQQQQQQKQRQQEQQQHQQQQQQPQPLKQQQQQQQQQPLQPQPLKQQPLQPLQPQPQPQPQKQQQRQQQRQQQPPRQQQKQQPLQQQGK", "length": 378 }, "evidence": [ { "id": "G3MZZ7", "url": "https://omabrowser.org/oma/group/G3MZZ7/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" } ], "go_annotation": { "categories": [ { "name": "Biological Process", "total": 1, "go_terms": [ { "name": "fertilization", "id": "GO:0009566", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0009566", "evidence": [ { "database": "UniProtKB", "id": "G3MZZ7", "url": "https://www.uniprot.org/uniprotkb/G3MZZ7" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 1, "go_terms": [ { "name": "acrosomal vesicle", "id": "GO:0001669", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0001669", "evidence": [ { "database": "UniProtKB", "id": "G3MZZ7", "url": "https://www.uniprot.org/uniprotkb/G3MZZ7" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 172, "end_pos": 174, "annotation": "n_glycosylation_sequon" }, { "start_pos": 173, "end_pos": 175, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [ { "pdb_id": "AF-G3MZZ7-F1", "pdb_chain": "global", "start_pos": 1, "end_pos": 289, "overlap": "1.0", "method": "AlphaFold", "type": "alphafold", "resolution": -1.0, "url": "https://data.glygen.org/ln2downloads/pdb/current/AF-G3MZZ7-F1.pdb", "url_external": "https://alphafold.ebi.ac.uk/entry/G3MZZ7" } ], "lectin_list": [], "domain_list": [], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "homologset.oma", "label": "OMA Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 172, "end_pos": 174 }, { "start_pos": 173, "end_pos": 175 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": 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"https://www.ebi.ac.uk/interpro/entry/IPR032675", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR050694", "url": "https://www.ebi.ac.uk/interpro/entry/IPR050694", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "G3N001", "url": "https://www.orthodb.org/?gene=G3N001", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR14224", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR14224", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR14224:SF27", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR14224:SF27", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF27089", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF27089", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "G3N001", "url": "https://www.uniprot.org/uniprotkb/G3N001", "database": "UniProtKB", 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"sequence": "AGAMQSLRFISAEALVSHPPGAQQSLDAVAHNLYPLLFKASYLLEQSAVIRLLLERWPLEEFRLGPLLGPSADHAGDLRDRACRACLEACVRGLADHVLQGGGRRRLRVADLTGIRDVQVQRCPCGRALGRWGRTELLARTCCELQKQPCATRRPIEVLADVFVTAGNFEVVARALGPSGPGSLRVRCLSLRADSLDPGQLLHVLRLAGPRELRRLEVVHNVRLHAGHVQQLLAQGGFPRLVSLTLPAKAFDAPPASTPASDGEEPLLASIAWALSRMTQLTELHMAFSTLTGKLQTLLGPLRTPLRVLDVGNCALNHEDMTFLANCIHAAHLEVLDLSGHCLVDLFPATFHRLLGQAAPTLRALTLEECGLEDRHVGALSLALGTCRRLRELRFLGNPLSGRALRRLFAALCELPRLRCVEFPVPRDCYPEGSAYPQDELAMSKFDQQKYDAIAADLRAVLLRAGRDDIQVSTPLFGSFDPDIQETSNELGAFLLQAFKTALENFSRVLKQME", "length": 514, "header": "tr|G3N001-1|G3N001_BOVIN Isoform 1 of Leucine-rich repeat-containing protein 14B OS=Bos taurus OX=9913 GN=LRRC14B PE=3 SV=2 CANONICAL=G3N001-1" }, "locus": { "chromosome": "20", "start_pos": 71853194, "end_pos": 71848284, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000064557.3", "url": "https://www.ensembl.org/id/ENSBTAT00000064557.3" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000055155.2", "url": "https://www.ensembl.org/id/ENSBTAP00000055155.2" } ] } } ], "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "other", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 258, "start_aa": "Thr", "end_pos": 258, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr258", "evidence": [ { "id": "", "database": "GlyGen", "url": "https://data.glygen.org/" } ], "filter_code": "000000000000000010000.00000000001000.0.01000" } ], "phosphorylation": [], "glycation": [], "keywords": [ "glycoprotein", "glycoprotein_predicted" ], "publication": [], "pathway": [], "orthologs": [], "go_annotation": {}, "pro_annotation": [], "site_annotation": [ { "start_pos": 505, "end_pos": 507, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], 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"MDPKAGGGEEDDCVDSGAETGGSDYSHVSSTSSEYSTEEVQDPFLVSIHIIADPGESRPLQEAIDKVLAWIHPDLPLFRVSERRACRRRRRVPKAAQPALAVVLFLQEEYGEEPILQLHRTLQRPPWRHHHTERVPGKFLPYLPCSQDFFTLAPGTPLWAIRPVHYGKEIVRFTIYCRHDNYADILKFYELILKRSPSQKKADFCIFPIFSNLDMDIQFSLKRLPCDQTPVPTDSSVLEFRVRDIGELVPLLPNPCSPISEGRWQTEDHDGNKILLQAQKGHRKRPKPGRAHQASEQKPCSTSSPRATAQSRTPGCCSQPPLDASHPGLSQAGPSTRHPQEFARRATSPPSLPWSFQRSKSLFCLPTGDPSPASAAEAQLSASIGGRGQRAPERGHGHLLSIDDLEGAQETDVDTGLRLSSSDLSVVSAYSAPSRFCSPEEAPHPPERGSGLWSERRGFREGPLPTAGGETAGASWATLPVFKGPSGSSATAVTAPPALDTSSLTETPPELPSDAPQAQQTGRDVLAPSVPAGCGDNDTEEFYI", "length": 544, "header": "tr|G3N0A0-1|G3N0A0_BOVIN Isoform 1 of Family with sequence similarity 124 member A OS=Bos taurus OX=9913 GN=FAM124A PE=3 SV=2 CANONICAL=G3N0A0-1" }, "isoforms": [ { "isoform_ac": "G3N0A0-1", "url": "https://www.uniprot.org/uniprotkb/G3N0A0/entry", "sequence": { "sequence": "MDPKAGGGEEDDCVDSGAETGGSDYSHVSSTSSEYSTEEVQDPFLVSIHIIADPGESRPLQEAIDKVLAWIHPDLPLFRVSERRACRRRRRVPKAAQPALAVVLFLQEEYGEEPILQLHRTLQRPPWRHHHTERVPGKFLPYLPCSQDFFTLAPGTPLWAIRPVHYGKEIVRFTIYCRHDNYADILKFYELILKRSPSQKKADFCIFPIFSNLDMDIQFSLKRLPCDQTPVPTDSSVLEFRVRDIGELVPLLPNPCSPISEGRWQTEDHDGNKILLQAQKGHRKRPKPGRAHQASEQKPCSTSSPRATAQSRTPGCCSQPPLDASHPGLSQAGPSTRHPQEFARRATSPPSLPWSFQRSKSLFCLPTGDPSPASAAEAQLSASIGGRGQRAPERGHGHLLSIDDLEGAQETDVDTGLRLSSSDLSVVSAYSAPSRFCSPEEAPHPPERGSGLWSERRGFREGPLPTAGGETAGASWATLPVFKGPSGSSATAVTAPPALDTSSLTETPPELPSDAPQAQQTGRDVLAPSVPAGCGDNDTEEFYI", "length": 544, "header": "tr|G3N0A0-1|G3N0A0_BOVIN Isoform 1 of Family with sequence similarity 124 member A OS=Bos taurus OX=9913 GN=FAM124A PE=3 SV=2 CANONICAL=G3N0A0-1" }, "locus": { "chromosome": "12", "start_pos": 20707132, "end_pos": 20592868, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000063043.4", "url": "https://www.ensembl.org/id/ENSBTAT00000063043.4" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000055257.2", "url": "https://www.ensembl.org/id/ENSBTAP00000055257.2" } ] } } ], "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "other", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 466, "start_aa": "Thr", "end_pos": 466, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr466", "evidence": [ { "id": "", "database": "GlyGen", "url": "https://data.glygen.org/" } ], "filter_code": "000000000000000010000.00000000001000.0.01000" } ], "phosphorylation": [], "glycation": [], "keywords": [ "glycoprotein", "glycoprotein_predicted" ], "publication": [], "pathway": [ { "id": "bta:539638", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?bta:539638", "resource": "KEGG Pathway" } ], "orthologs": [ { "uniprot_canonical_ac": "A0A0G2JV50-1", "protein_name": "Family with sequence similarity 124 member A", "gene_name": "Fam124a", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MNPKAAGEEEDCVDSGAETGGSDYSHLSSTSSELSVEEAQDPFLVSIHIIADPGESQPLQEAIDKVLAWVHPDLPLFRVSERRTSRRRRKSPKGAQPALAVVLFLQEEYGEEQILQVHRVLQQPPWRHHHTERVHGRFIPYLPCSQDFFTLAPGTPLWAIRPVHYGKEIVRFTIYCRHNSYADSLRFYELILRRSPSQRKADFCIFPIFSNLDVDIQFSLKRLPCDQKPVPTDSSVLEFRVKDIGQLVPLLPNPCSPISEGRWQTEDHDGNKILLQAQRAHKKGPKCSRAHHSSEKKPHSAPPAAIDTPNTGQGSSQTALRDSPSKQMAPLPGNKQEYSPQLNTSSPAWSFQRSKSLFCLPSGGTSTTEPQPLLTGSQRHSASEWKPSRLMSIDDLEGAQETDVDTGLRLSSSDLSVVSAYSAPSRFCNTVEASLSSEGCSSRWPAHKSPEKGPLPAASEVSPDTACVSHPLFTKGSPSPAEITTPGLSASGASLLTESSTPPPCHDPKATQGVQDIVLPPTTVGPEADDMEEFYI", "length": 536 }, "evidence": [ { "id": "G3N0A0", "url": "https://omabrowser.org/oma/group/G3N0A0/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "A0A1D5NXK4-1", "protein_name": "Family with sequence similarity 124 member A", "gene_name": "FAM124A", "tax_id": 9031, "organism": "Gallus gallus", "sequence": { "sequence": "MQQQQQQQPRGGEEDCGDSGAETGGSEYSRMSSTSSELSVEDIQDPFLVSVHIITDPGESKTLQQAIDKLLAWIHPELQLFRVSERRVSKKHRKPDKAGVSQPALAVILFLQEEYGEEPILQLHETFQRPPWHYHHTERVHGKFLPYMPCSQDFYTLAPETPLWAIRPVHYGKEIIRFTIYCRNENFVDILKFYELILKRPVCQKKADFCVFPIYSNMEIDIQFSLKKLPKGHVPMPTESAVLEFRVKDVGQLVPLLPNPCSPISEGRWQTEDHDGNRILLQQARSWCRKSAKQNKQPYPSVSTDSHFTTLPGFHPQSHQSVPEQPKEMSQNKVHHANGLGHYLGFSQQDLRHSDQEDFTRRSSSASSILWSFQRSKSLFCLPTVSSSSASETAHFSEAFQFLNTESPATRLKTWRCSPRLNIDDLEDAQETDVDTGRKLSFSDLSVVSAYSALNRFCNDLEASLPPQKQTCSTSTKASTSGRPVSTMCGTFDPMDGSLPSLSEWSSSSFMSASLSKQPKQSSRTASCSLDDCGSIFPASPTNDEEFYI", "length": 549 }, "evidence": [ { "id": "G3N0A0", "url": "https://omabrowser.org/oma/group/G3N0A0/", "database": "OMA" } ], "glygen_name": "Chicken", "common_name": "Chicken" }, { "uniprot_canonical_ac": "D3Z5V4-1", "protein_name": "Family with sequence similarity 124, member A", "gene_name": "Fam124a", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MNPKAGGEEEDCVDSGAETGGSDYSHLSSTSSELSVEEAQDPFLVSIHIIADPGESQPLQEAIDKVLAWVHPDLPLFRVSERRTTRRRRKSPKGAQPALAVVLFLQEEYGEEQILQVHRVLQQPPWRHHHTERVHGRFIPYLPCSQDFFTLAPGTPLWAIRPVHYGKEIVRFTIYCRHNSYTDSLRFYELILRRSPSQRKADFCIFPIFSNLDVDIQFSLKRLPCDQKPVPTDSSVLEFRVKDIGQLVPLLPNPCSPISEGRWQTEDHDGNKILLQAQRTHKKAPKYSRAHHSSEKKPHSAPPAAVDTPNTGQGSSQTALHDSPSNQIARLPGDKQEYNTQSSTSSPAWSFPRSKSLFCLPSGGPSPTEPQPLPTNSQRHSASEWKPSRLMSIDDLEGAQETDVDTGLRLSSSDLSVVSAYSAPSRFYNTIEAPLSSERCSSHWPAHKSPKKGPMPAASEVSPDTACVSHPLFTKGSPRPAETTTPALSASDASLLTESSTHTPCHDPKATQGVQGMLLPPTTVGPETDDMEEFYI", "length": 536 }, "evidence": [ { "id": "G3N0A0", "url": "https://omabrowser.org/oma/group/G3N0A0/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "F1Q587-1", "protein_name": "Protein FAM124A isoform X1", "gene_name": "fam124a", "tax_id": 7955, "organism": "Danio rerio", "sequence": { "sequence": "MENSVEDECADSGAETGGSDYSLMSSASSDLSMGDQQDPFLVSIHIITDPGQAKTLQQAADQVLSWLHPDLTLFRVSERAGGFSRKHKIRLQHVNELPSLQPALAIILFLQDEYGGEESLERLHSQLRCPPWRYHHTERVNGRGLLPLSAASQDFVTLAPGTPLWALRQVHYGKEIARFTVYCHYETYTEQVRLYRLLLRRKLAQKKEDFSFCVVYSNPETEIQLSFKRMPRGQSPAPTENAVMEIRVRDVGELVPLLPRPCTPISDVRWQTSDYDGNKILLQVQGSRCFRKHTIAKFYHLPSDDPSVTCPPPPEPPPPPPPYGRGPASYRNRRYHRNSSRLRSQTLPSPGSHSSRMAPPVLCEQDVHMERLQKDVELLRAGWASHRTQSLFSLHTDESRSSCASPLGFRPRCFSSMAAPLFRVNVDTLVGAEETDVDTGQTISGSSVDLSVVSGYTQPKLRPHLKAPAPRPKSAPPTDTGPDFADLMYNNSCYMRQTPAPPRAQSISTKFTPCVLNKPKPNSVCVSQPDRGQHKSNGFTPMDECSQEGTVEDEQEFYI", "length": 559 }, "evidence": [ { "id": "G3N0A0", "url": "https://omabrowser.org/oma/group/G3N0A0/", "database": "OMA" } ], "glygen_name": "Zebrafish", "common_name": "Zebrafish" }, { "uniprot_canonical_ac": "Q86V42-1", "protein_name": "Protein FAM124A", "gene_name": "FAM124A", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MDPKAGGGGEEDDCVDSGAETGGSDYSHLSSTSSELSVEEAQDPFLVSIHIIADPGESQPLQEAIDNVLAWIHPDLPLFRVSERRASRRRRKPPKGAQPALAVVLFLQEEYGEEQILQLHRTLQQPPWRHHHTEQVHGRFLPYLPCSQDFFTLAPGTPLWAIRPVHYGKEIVRFTVYCRYDNYADSLRFYQLILRRSPSQKKADFCIFPIFSNLDVDIQFSLKRLPCDQCPVPTDSSVLEFRVRDIGELVPLLPNPCSPISEGRWQTEDHDGNKILLQAQRVHKKFPKPGRVHHASEKKRHSTPLPSTAVPSHTPGSSQQSPLNSPHPGPIRTGLPPGHQQEFAGRANSTPNPPWSFQRSKSLFCLPTGGPSLASSAEPQWFSNTGAPGHRASEWRHGHLLSIDDLEGAQETDVDTGLRLSSSDLSVVSAYSAPSRFCSTVETPLPSERCSSHWAAHKDSREGPLPTVSRVTTEASWASLPFFTKRSSSSSATARAAPPAPSTSTLTDSSPQLPCDTPKVKQTDGDMPPPPGSAGPGDNDMEEFYI", "length": 546 }, "evidence": [ { "id": "G3N0A0", "url": "https://omabrowser.org/oma/group/G3N0A0/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" } ], "go_annotation": {}, "pro_annotation": [], "site_annotation": [ { "start_pos": 537, "end_pos": 539, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [ { "pdb_id": "AF-G3N0A0-F1", "pdb_chain": "global", "start_pos": 1, "end_pos": 544, "overlap": "1.0", "method": "AlphaFold", "type": "alphafold", "resolution": -1.0, "url": "https://data.glygen.org/ln2downloads/pdb/current/AF-G3N0A0-F1.pdb", "url_external": "https://alphafold.ebi.ac.uk/entry/G3N0A0" } ], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "G3N0A0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3N0A0" }, { "id": "PF15067", "database": "Pfam", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF15067" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "FAM124", "eco_id": "ECO_0000259", "start_pos": 46, "end_pos": 277, "start_aa": "Val", "end_aa": "Gln", "glycosite_overlap": [] } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "homologset.oma", "label": "OMA Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [ 466 ], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 537, "end_pos": 539 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 1 }, { "field": "total_sites", "count": 1 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 1 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "exact_sites", "count": 1 }, { "field": "exact_o_linked_sites", "count": 1 }, { "field": "fuzzy_sites", "count": 0 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_pos", "start_aa", "end_pos", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 1 }, { "field": "total_sites", "count": 1 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 1 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "exact_sites", "count": 1 }, { "field": "exact_o_linked_sites", "count": 1 }, { "field": "fuzzy_sites", "count": 0 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_pos", "start_aa", "end_pos", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ], "tool_support": { "graph_view": "yes" } }, { "uniprot_canonical_ac": "G3N0A1-1", "uniprot_ac": "G3N0A1", "uniprot_id": "G3N0A1_BOVIN", "mass": { "chemical_mass": 94936.0, "monoisotopic_mass": 94936.0 }, "refseq": { "ac": "XP_024844432", "name": "G-protein coupled receptor-associated sorting protein 2", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_024844432" }, "gene_names": [ { "name": "GPRASP2", "type": "recommended", "evidence": [ { "id": "G3N0A1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3N0A1" } ] }, { "name": "GPRASP2", "type": "synonym", "evidence": [ { "id": "XP_024844432", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_024844432" } ] } ], "protein_names": [ { "name": "G protein-coupled receptor associated sorting protein 2", "type": "synonym", "evidence": [ { "id": "G3N0A1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3N0A1/entry#names_and_taxonomy" } ] }, { "name": "G-protein coupled receptor-associated sorting protein 2", "type": "synonym", "evidence": [ { "id": "XP_024844432", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_024844432" } ] } ], "function": [], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Bos taurus", "taxid": 9913, "evidence": [ { "database": "UniProtKB", "id": "G3N0A1", "url": "https://www.uniprot.org/uniprotkb/G3N0A1" } ], "common_name": "Bovine", "glygen_name": "Bovine", "reference_species": "Bos taurus [9913]" } ], "gene": [ { "name": "GPRASP2", "url": "https://www.uniprot.org/uniprotkb/G3N0A1", "locus": { "chromosome": "X", "start_pos": 49908175, "end_pos": 49993437, "strand": "+", "evidence": [ { "database": "Ensembl Gene", "id": "ENSBTAG00000032852", "url": "https://www.ensembl.org/id/ENSBTAG00000032852" } ] } } ], "crossref": [ { "id": "ENSBTAG00000032852", "url": "https://bgee.org/?page=gene&gene_id=ENSBTAG00000032852", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "507696", "url": "https://www.ncbi.nlm.nih.gov/gene/507696", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR006911", "url": "https://www.ebi.ac.uk/interpro/entry/IPR006911", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR011989", "url": "https://www.ebi.ac.uk/interpro/entry/IPR011989", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR016024", "url": "https://www.ebi.ac.uk/interpro/entry/IPR016024", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR043374", "url": "https://www.ebi.ac.uk/interpro/entry/IPR043374", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "bta:507696", "url": "https://www.genome.jp/dbget-bin/www_bget?bta:507696", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "PTHR46414", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR46414", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR46414:SF1", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR46414:SF1", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF04826", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF04826", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "XP_024844432", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_024844432", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "G3N0A1", "url": "https://www.uniprot.org/uniprotkb/G3N0A1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "G3N0A1-1", "url": "https://www.uniprot.org/uniprotkb/G3N0A1-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MTGAEVEPVAQAKPEKKPGEEVVGGAERETEVPMVVRPKVRNQATSGARSKTESKATAGARPKTESQTMAGARPRTESQPMAGARPKTEFQAMPGARPKTEARAVGRARPKTEAKAIPGARPKDEAQVWAQTEFGAEAMLQSEGMPQTSVVAWPLVNTESGSVTKPMALSVDRELVNVDSETFPSSQVQTGIQPWFGSGEETSMGSWCYPRAKAREEASSESGFWSADETSTMSSFWAGEEASIRSWPREEANTRSRHRAKHQPNPRSRPRSKQDPFIDSWSGSEEESGNPFCLWAGENTNNLFRSRVRDEANMRSKLRTKREDFFESESEDEYYKESWFLPEEEANSRFRPRDKEAPNTVLKPRTQKVVNNSDRVKQETRFEEEVIIGSWFWAEKEASMEAGASAICESEAGAEEGAIGGSLFWTEENSSLGAVAREETRPESEEEAIFGSWFWDRDEACFDLNPRPVYKASPRFRDGAEEEVNVSSRPKTWEEVTVEFKPGPCHGVGFPSPSPFRIPEEATTSVYTELFEGKPKNVEVTPEGEEQESLLQSDQPDSEFPFQYDPSYRSVREIREHLRAKESAQPESWSCSCIQCELKIGPEEFEELLLLMDKIRDPFIHEISKIAMGMRTASQFTRDFIRDSGVVSLIETLLNYPSSRVRTSFLENMIHMAPPYPNLNMIETFVCQVCEETLAHSVGSPEQVLGLRMLRHLTSTTDYHTLVSNYMSGFLSLLTTGNARTKFHILKMLLNLSENPMVAKKLFSAKALSIFVGLFNIEETNDNIQIVIKMFQNISNIIKNGTMALIDDDFSLEPLISAFHEFEKLAEELQVQINNQSDPEVGQQS", "length": 845, "header": "tr|G3N0A1-1|G3N0A1_BOVIN Isoform 1 of G protein-coupled receptor associated sorting protein 2 OS=Bos taurus OX=9913 GN=GPRASP2 PE=3 SV=3 CANONICAL=G3N0A1-1" }, "isoforms": [ { "isoform_ac": "G3N0A1-1", "url": "https://www.uniprot.org/uniprotkb/G3N0A1/entry", "sequence": { "sequence": 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"MSSRIIKAISNLHVLQSSVKWHRVEQSATSLWDAYSGLISNQAMILALNSSFVDPALQFETQVKIIKSSFKMAFAVTNLDEVREIGMHEEDENDLENLYRTILNIFEDTLLILVSKDVYKLQFLKEMAVWMNEDNSYMQEEAMVVISRVLSFAARKVRGSASVNAPCLGVLAAELSLLCSHSDPSITQQAFVGMYHLLCIAKIQSGTAKSKNKKYDKPGNHCIQPSSSGTEFLPKNLQKDKSKIAQSVGKTLLPPLLTDFVWSLLMKLSVPDQSIASEAATILKLTLECNAHKVTMVSKIVDTIYKQLCGDDSPILREAMLRVITLLTRTSPKKVIFQLMDYPVPADDILILMWYAAGSESSVVPHVLKTILLILKGKPREMEKIITERKHFSLDATNMMPVAASQALCTLLPLGPYKKAVAQFFPQLLMALMLQLFYSSNLRLMTEDRPFYARDALRVLLNCSGLQEVDTALKRKNCWNQFSQVLFHHHGVYLVAKTLSEYNFPQFPETLHYLYKLAVEGPRRSEDSVITIIFFTELLNNFFKDPFPEKFLVLFRNWVNDPDPAVCKLSLQKIASMAPVINEIENVCSLLTSILDAFLSKDMTVIIRALITLRKLLDRLDKVTYSSLSTRIASSYCPLMDHGNEGIRSMAIRHFGQLLMDMSQYTWMLNDVVYAGLVPLILFLEDTEERVVKACKYTLKICASELKWSTLYFLKDEYYNFELVVLNICNNLLISHQKYITDLISETLGFLESSRTYLRRGSVILLGYLAKLGGHLLLRDEIDVMLEAIDRVIRDEDPVIRELAEKTNKIFMEIAYKLTTSNIKQSFQRLFNFIYLKKLKLLYNYNPPKDLTGSPMGIKEIRSDKAPQ", "length": 868, "header": "tr|G3N0D2-1|G3N0D2_BOVIN Isoform 1 of Maestro heat like repeat family member 9 OS=Bos taurus OX=9913 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"end_pos": 51, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [ { "pdb_id": "AF-G3N0D2-F1", "pdb_chain": "global", "start_pos": 1, "end_pos": 868, "overlap": "1.0", "method": "AlphaFold", "type": "alphafold", "resolution": -1.0, "url": "https://data.glygen.org/ln2downloads/pdb/current/AF-G3N0D2-F1.pdb", "url_external": "https://alphafold.ebi.ac.uk/entry/G3N0D2" } ], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "G3N0D2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3N0D2" }, { "id": "PF21047", "database": "Pfam", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF21047" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "Maestro-like HEAT-repeats", "eco_id": "ECO_0000259", "start_pos": 138, "end_pos": 368, "start_aa": "Met", "end_aa": "Leu", "glycosite_overlap": [] }, { "evidence": [ { "id": 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"database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001193834" } ] } ], "function": [ { "annotation": "Netrins control guidance of CNS commissural axons and peripheral motor axons.", "evidence": [ { "database": "UniProtKB", "id": "G3N0E7", "url": "https://www.uniprot.org/uniprotkb/G3N0E7#function" }, { "database": "UniProtKB", "id": "ARBA00059126", "url": "https://www.uniprot.org/uniprotkb/ARBA00059126#function" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Bos taurus", "taxid": 9913, "evidence": [ { "database": "UniProtKB", "id": "G3N0E7", "url": "https://www.uniprot.org/uniprotkb/G3N0E7" } ], "common_name": "Bovine", "glygen_name": "Bovine", "reference_species": "Bos taurus [9913]" } ], "gene": [ { "name": "NTN3", "url": "https://www.uniprot.org/uniprotkb/G3N0E7", "locus": { "chromosome": "25", "start_pos": 1978415, "end_pos": 1975605, "strand": "-", "evidence": [ { "database": "Ensembl Gene", "id": "ENSBTAG00000045625", "url": "https://www.ensembl.org/id/ENSBTAG00000045625" } ] } } ], "crossref": [ { "id": "G3N0E7", "url": "https://alphafold.ebi.ac.uk/entry/G3N0E7", "database": "AlphaFoldDB", "categories": [] }, { "id": "ENSBTAG00000045625", "url": "https://bgee.org/?page=gene&gene_id=ENSBTAG00000045625", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "cd00055", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd00055", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "cd03579", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd03579", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "787961", "url": "https://www.ncbi.nlm.nih.gov/gene/787961", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR000742", "url": "https://www.ebi.ac.uk/interpro/entry/IPR000742", "database": "InterPro", "categories": [ "Protein Classification" ] }, { 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"categories": [ "Protein Classification" ] }, { "id": "bta:787961", "url": "https://www.genome.jp/dbget-bin/www_bget?bta:787961", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "PTHR10574", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR10574", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR10574:SF292", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR10574:SF292", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00053", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00053", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF00055", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00055", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF01759", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF01759", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF24973", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF24973", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "NP_001193834", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001193834", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "G3N0E7", "url": "https://www.uniprot.org/uniprotkb/G3N0E7", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "G3N0E7-1", "url": "https://www.uniprot.org/uniprotkb/G3N0E7-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MPGWPWGLLLTAGTLSAALSPGPLAPADPCHDDGGAPRGCVPGLVNAALGREVLASSTCGRPATRACDASDPRRAHPAALLTSAGGTASPVCWRSDSLTQVPHNVTLTVPLGKAFELVFVSLRFCSAPPTSLALLKSQDHGRSWTPLGFFSSHCGLDYGRLPAPADGPAGPGPEALCFPAPQAQPDGGGLLAFSVQDGSPPGLDLDSSPVLQDWVTATDIQVVLTRPAVLGDTRGAMATAPYSYSATELQVGGRCKCNGHASRCLLDPQGHLTCDCRHGTEGPDCSRCKPFYCDRPWQRATAREAHACLACSCNGHARRCRFNMELYRLSGRRSGGVCLNCRHNTAGRHCHYCREGFYRDPGRALSDRRACRACDCHPVGAAGKTCNQTTGQCPCKDGVTGLTCNRCAPGFQQSRSPVAPCVKTPVPGPTEESSPVAPQDCDLHCKPARGSYRISLKKFCRKDYAVQVAVGARGEARGSWTRFPVAVLAVFRSGEERARRGSSALWVPARDAACGCPRLLPGRRYLLLGGGPGAAVGGPGGRGPGLSAARGSLVLPWRDAWTRRLRRLQRRERRGRCGAA", "length": 580, "header": "tr|G3N0E7-1|G3N0E7_BOVIN Isoform 1 of Netrin-3 OS=Bos taurus OX=9913 GN=NTN3 PE=4 SV=3 CANONICAL=G3N0E7-1" }, "isoforms": [ { "isoform_ac": "G3N0E7-1", "url": "https://www.uniprot.org/uniprotkb/G3N0E7/entry", "sequence": { "sequence": "MPGWPWGLLLTAGTLSAALSPGPLAPADPCHDDGGAPRGCVPGLVNAALGREVLASSTCGRPATRACDASDPRRAHPAALLTSAGGTASPVCWRSDSLTQVPHNVTLTVPLGKAFELVFVSLRFCSAPPTSLALLKSQDHGRSWTPLGFFSSHCGLDYGRLPAPADGPAGPGPEALCFPAPQAQPDGGGLLAFSVQDGSPPGLDLDSSPVLQDWVTATDIQVVLTRPAVLGDTRGAMATAPYSYSATELQVGGRCKCNGHASRCLLDPQGHLTCDCRHGTEGPDCSRCKPFYCDRPWQRATAREAHACLACSCNGHARRCRFNMELYRLSGRRSGGVCLNCRHNTAGRHCHYCREGFYRDPGRALSDRRACRACDCHPVGAAGKTCNQTTGQCPCKDGVTGLTCNRCAPGFQQSRSPVAPCVKTPVPGPTEESSPVAPQDCDLHCKPARGSYRISLKKFCRKDYAVQVAVGARGEARGSWTRFPVAVLAVFRSGEERARRGSSALWVPARDAACGCPRLLPGRRYLLLGGGPGAAVGGPGGRGPGLSAARGSLVLPWRDAWTRRLRRLQRRERRGRCGAA", "length": 580, "header": "tr|G3N0E7-1|G3N0E7_BOVIN Isoform 1 of Netrin-3 OS=Bos taurus OX=9913 GN=NTN3 PE=4 SV=3 CANONICAL=G3N0E7-1" }, "locus": { "chromosome": "25", "start_pos": 1978347, "end_pos": 1975804, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000063051.3", "url": "https://www.ensembl.org/id/ENSBTAT00000063051.3" }, { "database": "Ensembl Peptide", "id": 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], "common_name": "Bovine", "glygen_name": "Bovine", "reference_species": "Bos taurus [9913]" } ], "gene": [ { "name": "TEX50", "url": "https://www.uniprot.org/uniprotkb/G3N0F7", "locus": { "chromosome": "16", "start_pos": 55075616, "end_pos": 55073726, "strand": "-", "evidence": [ { "database": "Ensembl Gene", "id": "ENSBTAG00000046799", "url": "https://www.ensembl.org/id/ENSBTAG00000046799" } ] } } ], "crossref": [ { "id": "G3N0F7", "url": "https://alphafold.ebi.ac.uk/entry/G3N0F7", "database": "AlphaFoldDB", "categories": [] }, { "id": "ENSBTAG00000046799", "url": "https://bgee.org/?page=gene&gene_id=ENSBTAG00000046799", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "100336249", "url": "https://www.ncbi.nlm.nih.gov/gene/100336249", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR038833", "url": "https://www.ebi.ac.uk/interpro/entry/IPR038833", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": 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"16", "start_pos": 55075274, "end_pos": 55073849, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000064198.2", "url": "https://www.ensembl.org/id/ENSBTAT00000064198.2" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000055317.1", "url": "https://www.ensembl.org/id/ENSBTAP00000055317.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [ { "id": "bta:100336249", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?bta:100336249", "resource": "KEGG Pathway" } ], "orthologs": [ { "uniprot_canonical_ac": "A0A1B0GTY4-1", "protein_name": "Testis-expressed protein 50", "gene_name": "TEX50", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MSNQRLPLIFSLLFICFFGESFCICDGTVWTKVGWEILPEEVHYWKVKGSPSHCLPYLLDKLCCDFANMDIFQGCLYLIYNLLQAVFFVLFVLSVHYLWKKWKKHQKKLKKQASLEKPGNDLESPLINNIDQTLHRVATTASVIYKIWEHRSHHPSSKKIKHCKLKKKSKEEGARRY", "length": 177 }, "evidence": [ { "id": 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"cluster_types": [ { "name": "homologset.oma", "label": "OMA Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 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"id": "ENSBTAG00000047545", "url": "https://www.ensembl.org/id/ENSBTAG00000047545" } ] } } ], "crossref": [ { "id": "ENSBTAG00000047545", "url": "https://bgee.org/?page=gene&gene_id=ENSBTAG00000047545", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "100851574", "url": "https://www.ncbi.nlm.nih.gov/gene/100851574", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR032549", "url": "https://www.ebi.ac.uk/interpro/entry/IPR032549", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR032567", "url": "https://www.ebi.ac.uk/interpro/entry/IPR032567", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "bta:100851574", "url": "https://www.genome.jp/dbget-bin/www_bget?bta:100851574", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "PTHR15503", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR15503", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR15503:SF36", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR15503:SF36", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF16297", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF16297", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "XP_005228051", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_005228051", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "G3N0I0", "url": "https://www.uniprot.org/uniprotkb/G3N0I0", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "G3N0I0-1", "url": "https://www.uniprot.org/uniprotkb/G3N0I0-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MSEAAGNLNSLRMANVALREELNALRGENANLGLQLGRALAEVNSLRGNVSSYMRWPVPGVPALSEENFEFPLSEIDAAPEGELPFLCWPPPRTEPEYAPDELLISVIQDCSTSGAPTDPPPMPSPPPPALPPPPAKELPPQPLLPPLERPEIEPFSGDPVYLAEFLMQLETFIADHEDHFPGGAERVAFLISFFAGEAKDWAVSVTQEGSPLHANFPRFLDEIRKQFCGPIPPSVAKKAIRKLKQGDCTLGSYADAFQFLAQFLSWDDCRLQNQFLKGLSEFFRKELLWSTEMADLDELILECVEIERKVRVPKPMPLPGVRNIFFPFAADRNLEGEEGEECHSGDQDEEARRRRILNKDQRRRVRAIQQETSGEEEEKRRKREEEMRKELKQKGEEDGEEEEEEEEAEEKEEKEEEEEEGMRKKRKKEEEDQSKDKKEEEHEGGLQEPEQEPEQEPEQEQETEDETQDDDLDELMEMEPTYANASSQTSGYYHENFLDVTPPIIQPSRRRNQNRLPLLEGLPGINSPFYSSPPLIRRAGRLGQRQIRRRPPVLFRLTPRQGGHRAARGRIRV", "length": 574, "header": "tr|G3N0I0-1|G3N0I0_BOVIN Isoform 1 of Retrotransposon Gag like 5 OS=Bos taurus OX=9913 GN=RTL5 PE=4 SV=3 CANONICAL=G3N0I0-1" }, "isoforms": [ { "isoform_ac": "G3N0I0-1", "url": "https://www.uniprot.org/uniprotkb/G3N0I0/entry", "sequence": { "sequence": "MSEAAGNLNSLRMANVALREELNALRGENANLGLQLGRALAEVNSLRGNVSSYMRWPVPGVPALSEENFEFPLSEIDAAPEGELPFLCWPPPRTEPEYAPDELLISVIQDCSTSGAPTDPPPMPSPPPPALPPPPAKELPPQPLLPPLERPEIEPFSGDPVYLAEFLMQLETFIADHEDHFPGGAERVAFLISFFAGEAKDWAVSVTQEGSPLHANFPRFLDEIRKQFCGPIPPSVAKKAIRKLKQGDCTLGSYADAFQFLAQFLSWDDCRLQNQFLKGLSEFFRKELLWSTEMADLDELILECVEIERKVRVPKPMPLPGVRNIFFPFAADRNLEGEEGEECHSGDQDEEARRRRILNKDQRRRVRAIQQETSGEEEEKRRKREEEMRKELKQKGEEDGEEEEEEEEAEEKEEKEEEEEEGMRKKRKKEEEDQSKDKKEEEHEGGLQEPEQEPEQEPEQEQETEDETQDDDLDELMEMEPTYANASSQTSGYYHENFLDVTPPIIQPSRRRNQNRLPLLEGLPGINSPFYSSPPLIRRAGRLGQRQIRRRPPVLFRLTPRQGGHRAARGRIRV", "length": 574, "header": "tr|G3N0I0-1|G3N0I0_BOVIN Isoform 1 of Retrotransposon Gag like 5 OS=Bos taurus OX=9913 GN=RTL5 PE=4 SV=3 CANONICAL=G3N0I0-1" }, "locus": { "chromosome": "X", "start_pos": 78549538, "end_pos": 78549165, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000105939.1", "url": "https://www.ensembl.org/id/ENSBTAT00000105939.1" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000084716.1", "url": "https://www.ensembl.org/id/ENSBTAP00000084716.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [ { "id": "bta:100851574", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?bta:100851574", "resource": "KEGG Pathway" } ], "orthologs": [], "go_annotation": {}, "pro_annotation": [], "site_annotation": [ { "start_pos": 485, "end_pos": 487, "annotation": "n_glycosylation_sequon" }, { "start_pos": 49, "end_pos": 51, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "G3N0I0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3N0I0" }, { "id": "PF16297", "database": "Pfam", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF16297" } ], "ann_type": 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"categories": [ "Protein Classification" ] }, { "id": "PTHR24393:SF158", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR24393:SF158", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00096", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00096", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "XP_002694251", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_002694251", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "G3N0I5", "url": "https://www.uniprot.org/uniprotkb/G3N0I5", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "G3N0I5-1", "url": "https://www.uniprot.org/uniprotkb/G3N0I5-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": 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"MAQGDPQDGWGDASPLCSLTGEAYDPGMLSVNLESEDEAPGKAGDQGATGDPDQQARPRGSSQVTEDNPDLLWKHPACRKEEKFSDSFSAAGVGKKPMAPLRKKASWERDASKITPTEASPRASVTPSALPRGLARKWFGETQPPRASLPAGDEADSRANLDATLGVPSNFLGSARYFRAQKDGDKSPDNSSAGACVPKAGGSWDLSTQETHTPAQESATQACLAVEEALAKARKGSKDPNPAGSGEGRQGEARPYKCLRGGRAVQKSLGAKPYACELCGKAYSHRATLQQHQRLHTGERPYQCPFCDKTYTWSSDHRKHIRTHTGEKPYPCPDCGKAFVRSSDLRKHQRNMHSNDKPFPCAECGLTFNKPLSLLRHQRTHLGEKPFRCPTCDREFAVASRMMEHQRVHSGERPFPCPTCGKCFTKSSNLLEHQTLHTGQRPFKCADCGVAFAQPSRLARHQRIHTGERPFPCAQCGQAFARSSTLKRHQQIHSGEKGFLCAECGRAFRVASELAQHIRVHNGERPYQCADCGQAFTRSNHLRRHQAKHHSCKKEPTTPSSDDE", "length": 564, "header": "tr|G3N0I5-1|G3N0I5_BOVIN Isoform 1 of Zinc finger protein 648 OS=Bos taurus OX=9913 GN=ZNF648 PE=3 SV=1 CANONICAL=G3N0I5-1" }, "locus": { "chromosome": "16", "start_pos": 63171269, "end_pos": 63169578, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000065937.3", "url": "https://www.ensembl.org/id/ENSBTAT00000065937.3" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000055347.1", "url": "https://www.ensembl.org/id/ENSBTAP00000055347.1" } ] } } ], "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "other", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 126, "start_aa": "Thr", "end_pos": 126, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr126", "evidence": [ { "id": "", "database": "GlyGen", "url": "https://data.glygen.org/" } ], "filter_code": "000000000000000010000.00000000001000.0.01000" } ], "phosphorylation": [], "glycation": [], "keywords": [ "glycoprotein", "glycoprotein_predicted" ], "publication": [], "pathway": [ { "id": "bta:539756", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?bta:539756", "resource": "KEGG Pathway" } ], "orthologs": [ { "uniprot_canonical_ac": "D3Z0W3-1", "protein_name": "Zinc finger protein 648", "gene_name": "Zfp648", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MAQVDSQDRWTKVPLGSTQMLRMSLESEEEDGRKGGSPGTQNNTDSQFDTQSCKEEENWPECFSAGCVAQKPGEMPGKTSNGGKKASRITQIRDSPKLQEALGAPSRSLLHKVQIQPLRDSVGSDGGKKANKDPASEVPNSFLDSGGYFEAQNSVEASSLDKNSLEHFPRSESTLVQTPTIPASLLVKVRSSRKVQGQAGPEGSGQEEEGLDRCVRAFQKSTKVQVPAEHHGSKPYVCQLCGKAYSHRSTLQQHRRLHTGERPYRCPFCDKAYTWSSDHRKHIRTHTGEKPYGCPDCGRAFVRSSDLRKHQRNMHSNDKPFPCAQCGLTFNRPLSLLRHQRTHLGAKPFRCSSCGREFSVASRMVEHQRVHSGERPFPCSTCGKCFTKSSNLQEHQTLHTGQRPFKCTDCGVTFAQPSRLLRHQRIHTGERPFPCAECGQAFARSSTLKRHQQIHSGDKDFLCAECGRAFRIASELAQHIRMHNGERPYQCEGCGQTFTRSSHLQRHQAKHDTCKKEPVPSSSDE", "length": 525 }, "evidence": [ { "id": "G3N0I5", "url": "https://omabrowser.org/oma/group/G3N0I5/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "D3ZYA2-1", "protein_name": "Zinc finger protein 648", "gene_name": "Zfp648", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MAQVDSQERWTKVALGGMIRDSQTLSVNLESEEEDGREGGSPVTQNNTDLQFDTQSCKEEDNWSECFRAGCVEQRPGKIPRKTNNWGGRGWRITQTQDSPGLQEALGAPSRSFLYKVQMQPLRDSVGSDRVKKENKDPASEALTSFLDTGGSFGTQNSLEASSLDKNSLEHFPRFESTPAQTSSIPAGLAAGLVKAQGSRKAQGQVGPEGSRQEEEGPDRCVQGRRAFQKSSELQVSAEQRGIKPYVCQLCGKAYSHRSTLQQHRRLHTGERPYRCPFCDKAYTWSSDHRKHIRTHTGEKPYGCPDCGRAFVRSSDLRKHQRNMHSNDKPFPCAQCGLTFNRPLSLLRHQRTHLGAKPFRCSCCSREFSVASRMVEHQRVHSGERPFPCSICGKCFTKSSNLHEHQTLHTGQRPFKCADCGVTFAQPSRLLRHQRIHTGERPFPCAECGQAFARSSTLKRHQQTHSGDKDFLCAECGRAFRIASELAQHIRMHNGERPYQCEGCGQTFTRSSHLQRHQAKHDTCKEPVPSSSDE", "length": 534 }, "evidence": [ { "id": "G3N0I5", "url": "https://omabrowser.org/oma/group/G3N0I5/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "Q5T619-1", "protein_name": "Zinc finger protein 648", "gene_name": "ZNF648", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MAQVDSQDRWGEASPLSSLTEEAHDTQMLSMNLESDDEDGGEAEKEGTADPVACPRGSSPVTHENPDLPWPHPLGKEEEKFSDSSSAGGMGQKPVEMSGKASWSRDVTKINETQGSPGASRALGSLPSGLAHKLLGQMQPLGDRLPAGDDGYSGANQDAVLDVPPSFPSNGKYLCAHKSVDTSAGNSSLLCFPRPGSNWDLPTQETHTPAQASATPASLAAAVLAKARNSRKVQNQAGRREGGEAEARPYRCLRGGRAFQKPSKPLSPAETRGGAAKRYACELCGKAYSHRGTLQQHRRLHTGERPYQCSFCDKAYTWSSDHRKHIRTHTGEKPYPCPDCGKAFVRSSDLRKHQRNMHSNNKPFPCSECGLTFNKPLSLLRHQRTHLGAKPFRCPACDREFAVASRMVEHQRVHSGERPFPCPTCGKCFTKSSNLSEHQTLHTGQRPFKCADCGVAFAQPSRLVRHQRIHTGERPFPCTQCGQAFARSSTLKRHQQIHSGEKGFLCAECGRAFRIASELAQHIRMHNGERPYQCEDCGQAFTRSNHLQRHRAKHGTCKKEPIPSSSDE", "length": 568 }, "evidence": [ { "id": "G3N0I5", "url": "https://omabrowser.org/oma/group/G3N0I5/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" } ], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 1, "go_terms": [ { "name": "nucleus", "id": "GO:0005634", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005634", "evidence": [ { "database": "UniProtKB", "id": "G3N0I5", "url": "https://www.uniprot.org/uniprotkb/G3N0I5" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 2, "go_terms": [ { "name": "DNA-templated transcription", "id": "GO:0006351", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006351", "evidence": [ { "database": "UniProtKB", "id": "G3N0I5", "url": "https://www.uniprot.org/uniprotkb/G3N0I5" } ], "pmid": "" }, { "name": "regulation of transcription by RNA polymerase II", "id": "GO:0006357", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006357", "evidence": [ { "database": "UniProtKB", "id": "G3N0I5", "url": "https://www.uniprot.org/uniprotkb/G3N0I5" } ], "pmid": "" } ] }, { "name": "Molecular Function", "total": 3, "go_terms": [ { "name": "zinc ion binding", "id": "GO:0008270", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008270", "evidence": [ { "database": "UniProtKB", "id": "G3N0I5", "url": "https://www.uniprot.org/uniprotkb/G3N0I5" } ], "pmid": "" }, { "name": "RNA polymerase II cis-regulatory region sequence-specific DNA binding", "id": "GO:0000978", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000978", "evidence": [ { "database": "UniProtKB", "id": "G3N0I5", "url": "https://www.uniprot.org/uniprotkb/G3N0I5" } ], "pmid": "" }, { "name": "DNA-binding transcription factor activity, RNA polymerase II-specific", "id": "GO:0000981", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000981", "evidence": [ { "database": "UniProtKB", "id": "G3N0I5", "url": "https://www.uniprot.org/uniprotkb/G3N0I5" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 190, "end_pos": 192, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [ { "pdb_id": "AF-G3N0I5-F1", "pdb_chain": "global", "start_pos": 1, "end_pos": 564, "overlap": "1.0", "method": "AlphaFold", "type": "alphafold", "resolution": -1.0, "url": 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217 OS=Bos taurus OX=9913 GN=TMEM217B PE=4 SV=3 CANONICAL=G3N0P9-1" }, "locus": { "chromosome": "23", "start_pos": 11109870, "end_pos": 11109319, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000063778.3", "url": "https://www.ensembl.org/id/ENSBTAT00000063778.3" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000055415.3", "url": "https://www.ensembl.org/id/ENSBTAP00000055415.3" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [ { "id": "bta:132342084", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?bta:132342084", "resource": "KEGG Pathway" } ], "orthologs": [], "go_annotation": {}, "pro_annotation": [], "site_annotation": [], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [ { "pdb_id": "AF-G3N0P9-F1", "pdb_chain": "global", "start_pos": 1, "end_pos": 184, "overlap": 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"type": "recommended", "evidence": [ { "id": "G3N0Q1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3N0Q1" } ] }, { "name": "GALNTL5", "type": "synonym", "evidence": [ { "id": "NP_001069909", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001069909" } ] } ], "protein_names": [ { "name": "N-acetylgalactosaminyltransferase-like protein 5", "type": "synonym", "evidence": [ { "id": "NP_001069909", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001069909" } ] }, { "name": "Polypeptide N-acetylgalactosaminyltransferase like 5", "type": "synonym", "evidence": [ { "id": "G3N0Q1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3N0Q1/entry#names_and_taxonomy" } ] }, { "name": "UDP-N-acetyl-alpha-D-galactosamine:polypeptide N-acetylgalactosaminyltransferase-like 5", "type": "synonym", "evidence": [ { "id": "NP_001069909", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001069909" } ] }, { "name": "inactive polypeptide N-acetylgalactosaminyltransferase-like protein 5", "type": "synonym", "evidence": [ { "id": "NP_001069909", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001069909" } ] } ], "function": [], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Bos taurus", "taxid": 9913, "evidence": [ { "database": "UniProtKB", "id": "G3N0Q1", "url": "https://www.uniprot.org/uniprotkb/G3N0Q1" } ], "common_name": "Bovine", "glygen_name": "Bovine", "reference_species": "Bos taurus [9913]" } ], "gene": [ { "name": "GALNTL5", "url": "https://www.uniprot.org/uniprotkb/G3N0Q1", "locus": { "chromosome": "4", "start_pos": 114533940, "end_pos": 114477816, "strand": "-", "evidence": [ { "database": "Ensembl Gene", "id": "ENSBTAG00000045535", "url": "https://www.ensembl.org/id/ENSBTAG00000045535" } ] } } ], "crossref": [ { "id": "G3N0Q1", "url": "https://alphafold.ebi.ac.uk/entry/G3N0Q1", "database": "AlphaFoldDB", "categories": [] }, { "id": "ENSBTAG00000045535", "url": "https://bgee.org/?page=gene&gene_id=ENSBTAG00000045535", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "cd02510", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd02510", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "617031", "url": "https://www.ncbi.nlm.nih.gov/gene/617031", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR001173", "url": "https://www.ebi.ac.uk/interpro/entry/IPR001173", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR029044", "url": "https://www.ebi.ac.uk/interpro/entry/IPR029044", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR045885", "url": "https://www.ebi.ac.uk/interpro/entry/IPR045885", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "bta:617031", "url": "https://www.genome.jp/dbget-bin/www_bget?bta:617031", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "FNWHLQF", "url": "https://omabrowser.org/oma/group/FNWHLQF/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "PTHR11675", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR11675", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR11675:SF17", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR11675:SF17", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00535", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00535", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "R-BTA-913709", "url": "https://www.reactome.org/PathwayBrowser/#R-BTA-913709", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "NP_001069909", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001069909", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "G3N0Q1", "url": "https://www.uniprot.org/uniprotkb/G3N0Q1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "G3N0Q1-1", "url": "https://www.uniprot.org/uniprotkb/G3N0Q1-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MRNVIIQCLLCASLTFGIWIAVFNIYLHYNHVKKQEKIQEKGNPLIWSLGEKLQSKPDSVHLPRAYNVRVERASEDEPAEPKLLLSSGENFNYSIPEVIHGYSTYGFNSIISKNLGHYRNVPDTRNVMCQKKMYPAKLPTASIIICFHNEEFNALFRTLSSIMTLTQQYILEEIILVDDMSDFDDLKEKLDYHLEIFRGKIKLIRNKKREGLIRARMTGASHASGDVLVFLDSHCEVNKVWLEPLLNAIAKDPKMVVCPLIDVIDYMTLEYQPSPIVRGAFNWRLEFKWDHVLSYEIEGPEGPTTPIRSPAMAGGIFAINRHYFNEIGQYDKGMNLWGGENLELSLRIWMCGGQLYVIPCSRVGHINRQHMTNRFEIMEVVEYNNLRLVHTWLDEYKGQFFLRRPALKSAAYGNISERVELRKRLGCKSFQWYLDTIFPELEASKAIS", "length": 448, "header": "tr|G3N0Q1-1|G3N0Q1_BOVIN Isoform 1 of Polypeptide N-acetylgalactosaminyltransferase like 5 OS=Bos taurus OX=9913 GN=GALNTL5 PE=3 SV=2 CANONICAL=G3N0Q1-1" }, "isoforms": [ { "isoform_ac": "G3N0Q1-1", "url": "https://www.uniprot.org/uniprotkb/G3N0Q1/entry", "sequence": { "sequence": "MRNVIIQCLLCASLTFGIWIAVFNIYLHYNHVKKQEKIQEKGNPLIWSLGEKLQSKPDSVHLPRAYNVRVERASEDEPAEPKLLLSSGENFNYSIPEVIHGYSTYGFNSIISKNLGHYRNVPDTRNVMCQKKMYPAKLPTASIIICFHNEEFNALFRTLSSIMTLTQQYILEEIILVDDMSDFDDLKEKLDYHLEIFRGKIKLIRNKKREGLIRARMTGASHASGDVLVFLDSHCEVNKVWLEPLLNAIAKDPKMVVCPLIDVIDYMTLEYQPSPIVRGAFNWRLEFKWDHVLSYEIEGPEGPTTPIRSPAMAGGIFAINRHYFNEIGQYDKGMNLWGGENLELSLRIWMCGGQLYVIPCSRVGHINRQHMTNRFEIMEVVEYNNLRLVHTWLDEYKGQFFLRRPALKSAAYGNISERVELRKRLGCKSFQWYLDTIFPELEASKAIS", "length": 448, "header": "tr|G3N0Q1-1|G3N0Q1_BOVIN Isoform 1 of Polypeptide N-acetylgalactosaminyltransferase like 5 OS=Bos taurus OX=9913 GN=GALNTL5 PE=3 SV=2 CANONICAL=G3N0Q1-1" }, "locus": { "chromosome": "4", "start_pos": 114533803, "end_pos": 114482065, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000064511.3", "url": "https://www.ensembl.org/id/ENSBTAT00000064511.3" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000055417.2", "url": "https://www.ensembl.org/id/ENSBTAP00000055417.2" } ] } } ], "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "other", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 304, "start_aa": "Thr", "end_pos": 304, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr304", "evidence": [ { "id": "", "database": "GlyGen", "url": "https://data.glygen.org/" } ], "filter_code": "000000000000000010000.00000000001000.0.01000" } ], "phosphorylation": [], "glycation": [], "keywords": [ "glycoprotein", "glycoprotein_predicted" ], "publication": [], "pathway": [ { "id": "bta:617031", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?bta:617031", "resource": "KEGG Pathway" }, { "id": "R-BTA-913709", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-BTA-913709", "resource": "Reactome", "description": "O-linked glycosylation of mucins" } ], "orthologs": [ { "uniprot_canonical_ac": "F1SSN3-1", "protein_name": "Polypeptide N-acetylgalactosaminyltransferase like 5", "gene_name": "GALNTL5", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MRNVIIQSLLYGSLTLGVWTALFGIYFHHNNVKNQEKKIQTKGNPLIWSLGEKLQEQSIHGSMQIRRPRERLNEDETEEQKPISVLGEDFNYTDTELIYGYMKYGFNHIVSKSLGNYRNVPDSRNKMCHQKHYPANLPTASIIICFHNEEFNALLRTVSSIMTLTPHHIIEEIILVDDMSEYDDLKEKLDYHLEIFRGKIKVIRNKKREGLIRARLVGASRASGDILVFLDSHCEVNKIWLEPLLDAIVKDPKMVVCPIMDVIDYVTLEYKPSPVVRGVFNWHLQFEWDRVFSYEMDGPDGPTRPIRSPAMVGGLFAIHRHYFNEIGQYDKGMNLWGGENLELSLRIWMCGGQLFLLPCSRVGHINKPYFTNQGEIKKAMAYNNLRIVHVWLDEYKEQFFLQNPRLKSLAYGNVSERVELRKRLGCKSFQWYLDTVFPELETSNSI", "length": 446 }, "evidence": [ { "id": "G3N0Q1", "url": "https://omabrowser.org/oma/group/G3N0Q1/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "Q7Z4T8-1", "protein_name": "Inactive polypeptide N-acetylgalactosaminyltransferase-like protein 5", "gene_name": "GALNTL5", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MRNAIIQGLFYGSLTFGIWTALLFIYLHHNHVSSWQKKSQEPLSAWSPGKKVHQQIIYGSEQIPKPHVIVKRTDEDKAKSMLGTDFNHTNPELHKELLKYGFNVIISRSLGIEREVPDTRSKMCLQKHYPARLPTASIVICFYNEECNALFQTMSSVTNLTPHYFLEEIILVDDMSKVDDLKEKLDYHLETFRGKVKIIRNKKREGLIRARLIGASHASGDVLVFLDSHCEVNRVWLEPLLHAIAKDPKMVVCPLIDVIDDRTLEYKPSPLVRGTFDWNLQFKWDNVFSYEMDGPEGSTKPIRSPAMSGGIFAIRRHYFNEIGQYDKDMDFWGRENLELSLRIWMCGGQLFIIPCSRVGHISKKQTGKPSTIISAMTHNYLRLVHVWLDEYKEQFFLRKPGLKYVTYGNIRERVELRKRLGCKSFQWYLDNVFPELEASVNSL", "length": 443 }, "evidence": [ { "id": "G3N0Q1", "url": "https://omabrowser.org/oma/group/G3N0Q1/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "Q9D4M9-1", "protein_name": "Inactive polypeptide N-acetylgalactosaminyltransferase-like protein 5", "gene_name": "Galntl5", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MKSVIIQGLFCGFLAIGLWASMLLLFLHLEQEDMLENEKEELLKKRSLGKNAHQQTRHSEDVTHDEVNFSDPELIQGLRRYGLNAIMSRRLGIEREVPDSRDKICQQKHYPFNLPTASIIICFYNEEFNTLLRAVSSVVNLSPQHLLEEIILVDDMSEFDDLKDKLDYYLEIFRGKVKLIRNKKREGLIRSKMIGASRASGDILVFLDSHCEVNRVWLEPLLHAIAKDHKMVVCPIIDVINELTLDYMAAPIVRGAFDWNLNLRWDNVFAYELDGPEGPSTPIRSPAMTGGIFAINRHYFNELGQYDNGMDICGGENVELSLRIWMCGGQLFILPCSRVGYNSKALSQHRRANQSALSRNLLRVVHVWLDEYKGNFFLQRPSLTYVSCGNISERVELRKRLGCKSFQWYLDNIFPELEPFNTERKRKKNRF", "length": 431 }, "evidence": [ { "id": "G3N0Q1", "url": "https://omabrowser.org/oma/group/G3N0Q1/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" } ], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 1, "go_terms": [ { "name": "Golgi apparatus", "id": "GO:0005794", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005794", "evidence": [ { "database": "UniProtKB", "id": "G3N0Q1", "url": "https://www.uniprot.org/uniprotkb/G3N0Q1" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 1, "go_terms": [ { "name": "spermatid development", "id": "GO:0007286", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007286", "evidence": [ { "database": "UniProtKB", "id": "G3N0Q1", "url": "https://www.uniprot.org/uniprotkb/G3N0Q1" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 414, "end_pos": 416, "annotation": "n_glycosylation_sequon" }, { "start_pos": 92, "end_pos": 94, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [ { "pdb_id": "AF-G3N0Q1-F1", "pdb_chain": "global", "start_pos": 1, "end_pos": 448, "overlap": "1.0", "method": "AlphaFold", "type": "alphafold", "resolution": -1.0, "url": "https://data.glygen.org/ln2downloads/pdb/current/AF-G3N0Q1-F1.pdb", "url_external": "https://alphafold.ebi.ac.uk/entry/G3N0Q1" } ], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "G3N0Q1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3N0Q1" }, { "id": "PF00535", "database": "Pfam", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00535" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "Glycosyltransferase 2-like", "eco_id": "ECO_0000259", "start_pos": 142, "end_pos": 324, "start_aa": "Ser", "end_aa": "Phe", "glycosite_overlap": [] } ], "binding_sites": [], "synthesized_glycans": [ { "glytoucan_ac": "G00027JG", "type": "Other", "subtype": "Other" }, { "glytoucan_ac": "G00030VN", "type": "O-linked", "subtype": "Core 3" }, { "glytoucan_ac": "G00031MO", "type": "O-linked", "subtype": "Core 1" }, { "glytoucan_ac": "G00032MO", "type": "O-linked", "subtype": "Core 1" }, { "glytoucan_ac": "G00033MO", "type": "O-linked", "subtype": "Core 2" }, { "glytoucan_ac": "G00034MO", "type": "O-linked", "subtype": "Core 2" }, { "glytoucan_ac": "G00034UM", "type": "O-linked", "subtype": "Core 2" }, { "glytoucan_ac": "G00035MO", "type": "O-linked", "subtype": "Core 3" }, { "glytoucan_ac": "G00036MO", "type": "O-linked", "subtype": "Core 3" }, { "glytoucan_ac": "G00037MO", "type": "O-linked", "subtype": "Core 4" }, { "glytoucan_ac": "G00038MO", "type": "O-linked", "subtype": "Core 4" }, { "glytoucan_ac": "G00039MO", "type": "O-linked", "subtype": "Core 5" }, { "glytoucan_ac": "G00040MO", "type": "O-linked", "subtype": "Core 5" }, { "glytoucan_ac": "G00041IL", "type": "O-linked", "subtype": "Core 3" }, { "glytoucan_ac": "G00041MO", "type": "O-linked", "subtype": "Core 6" }, { "glytoucan_ac": "G00042MO", "type": "O-linked", "subtype": "Core 6" }, { "glytoucan_ac": "G00043MO", "type": "O-linked", "subtype": "Core 7" }, { "glytoucan_ac": "G00044MO", "type": "O-linked", "subtype": "Core 7" }, { "glytoucan_ac": "G00063MO", "type": "Other", "subtype": "Other" }, { "glytoucan_ac": "G00069YC", "type": "O-linked", "subtype": "Core 2" }, { "glytoucan_ac": "G00079IK", "type": "O-linked", "subtype": "Core 2" }, { "glytoucan_ac": "G00094SE", "type": "O-linked", "subtype": "Core 2" }, { "glytoucan_ac": "G00112IO", "type": "O-linked", "subtype": "Core 3" }, { "glytoucan_ac": "G00139WK", "type": "O-linked", "subtype": "Core 1" }, { "glytoucan_ac": "G00140UB", "type": "O-linked", "subtype": "Core 7" }, { "glytoucan_ac": "G00140YZ", "type": "O-linked", "subtype": "Core 2" }, { "glytoucan_ac": "G00164QP", "type": "O-linked", "subtype": "Core 2" }, { "glytoucan_ac": "G00196CO", "type": "O-linked", "subtype": "Core 2" }, { "glytoucan_ac": "G00219VH", "type": "O-linked", "subtype": "Core 3" }, { "glytoucan_ac": "G00230IL", "type": "O-linked", "subtype": "Core 2" }, { "glytoucan_ac": "G00234GG", "type": "O-linked", "subtype": "Core 4" }, { "glytoucan_ac": "G00238CK", "type": "O-linked", "subtype": "Core 2" }, { "glytoucan_ac": "G00241VQ", "type": "O-linked", "subtype": "Core 2" }, { "glytoucan_ac": "G00249XF", "type": "O-linked", "subtype": "Core 4" }, { "glytoucan_ac": "G00257RE", "type": "O-linked", "subtype": "Core 4" }, { "glytoucan_ac": "G00257UQ", "type": "O-linked", "subtype": "Core 2" }, { "glytoucan_ac": "G00277SO", "type": "O-linked", "subtype": "Core 2" }, { "glytoucan_ac": "G00287UD", "type": "O-linked", "subtype": "Core 1" }, { "glytoucan_ac": "G00288RP", "type": "O-linked", "subtype": "Core 6" }, { "glytoucan_ac": "G00318OS", "type": "O-linked", "subtype": "Core 2" }, { "glytoucan_ac": "G00321UH", "type": "O-linked", "subtype": "Core 3" }, { "glytoucan_ac": "G00335JE", "type": "O-linked", "subtype": "Core 2" }, { "glytoucan_ac": "G00371DJ", "type": "O-linked", "subtype": "Core 3" }, { "glytoucan_ac": "G00372ZO", "type": "O-linked", "subtype": "Core 2" }, { "glytoucan_ac": "G00376RB", "type": "O-linked", "subtype": "Core 2" }, { "glytoucan_ac": "G00379PJ", "type": "O-linked", "subtype": "Core 8" }, { "glytoucan_ac": "G00383NC", "type": "O-linked", "subtype": "Core 3" }, { "glytoucan_ac": "G00387BU", "type": "Other", "subtype": "Other" }, { "glytoucan_ac": "G00390EC", "type": "O-linked", 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"type": "O-linked", "subtype": "Core 8" }, { "glytoucan_ac": "G00569WM", "type": "O-linked", "subtype": "Core 3" }, { "glytoucan_ac": "G00598IA", "type": "O-linked", "subtype": "Core 4" }, { "glytoucan_ac": "G00641XC", "type": "O-linked", "subtype": "Core 6" }, { "glytoucan_ac": "G00652BK", "type": "O-linked", "subtype": "Core 2" }, { "glytoucan_ac": "G00653TI", "type": "O-linked", "subtype": "Core 2" }, { "glytoucan_ac": "G00654GN", "type": "O-linked", "subtype": "Core 2" }, { "glytoucan_ac": "G00660CI", "type": "O-linked", "subtype": "Core 2" }, { "glytoucan_ac": "G00675GF", "type": "O-linked", "subtype": "Core 9" }, { "glytoucan_ac": "G00682IE", "type": "O-linked", "subtype": "Core 1" }, { "glytoucan_ac": "G00707RC", "type": "O-linked", "subtype": "Core 2" }, { "glytoucan_ac": "G00728SN", "type": "O-linked", "subtype": "Core 2" }, { "glytoucan_ac": "G00729SA", "type": "O-linked", "subtype": "Core 2" }, { "glytoucan_ac": "G00745CN", "type": "O-linked", "subtype": "Core 3" }, { 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"subtype": "Core 4" }, { "glytoucan_ac": "G00907IC", "type": "O-linked", "subtype": "Core 2" }, { "glytoucan_ac": "G00924FH", "type": "O-linked", "subtype": "Core 3" }, { "glytoucan_ac": "G00932UQ", "type": "O-linked", "subtype": "Core 2" }, { "glytoucan_ac": "G00944OL", "type": "O-linked", "subtype": "Core 2" }, { "glytoucan_ac": "G00950FJ", "type": "O-linked", "subtype": "Core 2" }, { "glytoucan_ac": "G00952LS", "type": "Other", "subtype": "Other" }, { "glytoucan_ac": "G00967VH", "type": "O-linked", "subtype": "Core 1" }, { "glytoucan_ac": "G00978GW", "type": "O-linked", "subtype": "Core 2" }, { "glytoucan_ac": "G00979XR", "type": "O-linked", "subtype": "Core 2" }, { "glytoucan_ac": "G00980BE", "type": "O-linked", "subtype": "Core 2" }, { "glytoucan_ac": "G00987AB", "type": "O-linked", "subtype": "Core 8" }, { "glytoucan_ac": "G00997UP", "type": "O-linked", "subtype": "Core 2" }, { "glytoucan_ac": "G01004EH", "type": "O-linked", "subtype": "Core 8" }, { "glytoucan_ac": "G01033BK", 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"https://www.ensembl.org/id/ENSBTAG00000048216" } ] } } ], "crossref": [ { "id": "ENSBTAG00000048216", "url": "https://bgee.org/?page=gene&gene_id=ENSBTAG00000048216", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "cd18912", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd18912", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "100301293", "url": "https://www.ncbi.nlm.nih.gov/gene/100301293", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR011598", "url": "https://www.ebi.ac.uk/interpro/entry/IPR011598", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR036638", "url": "https://www.ebi.ac.uk/interpro/entry/IPR036638", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR050283", "url": "https://www.ebi.ac.uk/interpro/entry/IPR050283", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "bta:100301293", "url": "https://www.genome.jp/dbget-bin/www_bget?bta:100301293", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "GNWRRCP", "url": "https://omabrowser.org/oma/group/GNWRRCP/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "G3N0S4", "url": "https://www.orthodb.org/?gene=G3N0S4", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR23349", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR23349", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR23349:SF10", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR23349:SF10", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00010", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00010", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "XP_002695754", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_002695754", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "G3N0S4", "url": "https://www.uniprot.org/uniprotkb/G3N0S4", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "G3N0S4-1", "url": "https://www.uniprot.org/uniprotkb/G3N0S4-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MHRGAPGPGLRGLKGAEGSPQDLGNSCLEAERDFGVLRENGGPRGLGEAEEVAGSRKRSRPVRSKARRMAANVRERRRILDYNEAFNALRRALRHDLGGKRLSKIATLRRAIHRIAALSLVLRASPAPRWPCGHQECHRQAARAGDAGDLGSSPPAPPPPAGPFAPRCASCHPHTPLGRPRAVAEALPGWAQASPGSWRRSLGAPSAWPRGLLRAGPGLGHQHS", "length": 224, "header": "tr|G3N0S4-1|G3N0S4_BOVIN Isoform 1 of Class A basic helix-loop-helix protein 9 OS=Bos taurus OX=9913 GN=BHLHA9 PE=4 SV=1 CANONICAL=G3N0S4-1" }, "isoforms": [ { "isoform_ac": "G3N0S4-1", "url": "https://www.uniprot.org/uniprotkb/G3N0S4/entry", "sequence": { "sequence": "MHRGAPGPGLRGLKGAEGSPQDLGNSCLEAERDFGVLRENGGPRGLGEAEEVAGSRKRSRPVRSKARRMAANVRERRRILDYNEAFNALRRALRHDLGGKRLSKIATLRRAIHRIAALSLVLRASPAPRWPCGHQECHRQAARAGDAGDLGSSPPAPPPPAGPFAPRCASCHPHTPLGRPRAVAEALPGWAQASPGSWRRSLGAPSAWPRGLLRAGPGLGHQHS", "length": 224, "header": "tr|G3N0S4-1|G3N0S4_BOVIN Isoform 1 of Class A basic helix-loop-helix protein 9 OS=Bos taurus OX=9913 GN=BHLHA9 PE=4 SV=1 CANONICAL=G3N0S4-1" }, "locus": { "chromosome": "19", "start_pos": 21628764, "end_pos": 21628093, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000094705.1", "url": "https://www.ensembl.org/id/ENSBTAT00000094705.1" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000083684.1", "url": "https://www.ensembl.org/id/ENSBTAP00000083684.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [ { "id": "bta:100301293", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?bta:100301293", "resource": "KEGG Pathway" } ], "orthologs": [ { "uniprot_canonical_ac": "D3ZY30-1", "protein_name": "Class A basic helix-loop-helix protein 9", "gene_name": "Bhlha9", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MLRGTPGLGLRGLKRGEDSVGDLGHSCPEAGRNFGVLRRSLAEEEEVAGRKRERPARSKARRMAANVRERKRILDYNEAFNALRRALQHDLGGKRLSKIATLRRAIHRITALSLVLRASPAPRWPCGHLECHGQAAHGSSAGDSGFSVPRSVLSPAAPSLARRDTASPLVPPAPRCASCSPNAHLGRPRMMAEVPSLAQASGGSWRRCPGAAPVGSIQWRWGSGLGYQHS", "length": 230 }, "evidence": [ { "id": "G3N0S4", "url": "https://omabrowser.org/oma/group/G3N0S4/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "F1RHK4-1", "protein_name": "Class A basic helix-loop-helix protein 9", "gene_name": "BHLHA9", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MHRGAPGPGLGGLKGAEDSAEDLGNACLGARREFGVLRENGQPCGLGEAEETAGGRRRSRPVRSKARRMAANVRERKRILDYNEAFNALRRALRHDLGGKRLSKIATLRRAIHRITALSLVLRASPTPRWPCGHLECHGQAARAGDAGDPGCRPPQPAPLPAGPFAPRCASCFPHAPLGRPTAVAEAQGAAQTSAGSWRRCPGAPSAWPRGHLRAGPGMGYQHS", "length": 224 }, "evidence": [ { "id": "G3N0S4", "url": "https://omabrowser.org/oma/group/G3N0S4/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "G3HR90-1", "protein_name": "Class A basic helix-loop-helix protein 9", "gene_name": "Bhlha9", "tax_id": 10029, "organism": "Cricetulus griseus", "sequence": { "sequence": "MLRGTPGLSLRDLKWSEGSVEDLGRSCPEADRNFGVLRRSLDEAEEAAGRKRERPARSKARRMAANVRERKRILDYNEAFNALRRALQHDLGGKRLSKIATLRRAIHRITALSLVLRASPAPRWPCSHLECHSQAAHGSGAEDSGFRAPLSTPPPAVPGLARRGVTSSLVPPAPLCASCSPHAHLGRPRVMAEGPSLAQASGGSWRRCPGAPPVGPIPWRWGSGLGYQHS", "length": 230 }, "evidence": [ { "id": "G3N0S4", "url": "https://omabrowser.org/oma/group/G3N0S4/", "database": "OMA" } ], "glygen_name": "Hamster", "common_name": "Chinese hamster" }, { "uniprot_canonical_ac": "Q5RJB0-1", "protein_name": "Class A basic helix-loop-helix protein 9", "gene_name": "Bhlha9", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MLRGTPGLGLGGLNRAEDFVEDLGRSCSEAGRNFGVLRRSSLDEAEEAAGRKRERPTRSKARRMAANVRERKRILDYNEAFNALRRALQHDLGGKRLSKIATLRRAIHRITALSLVLRASPAPRWPCGHLECHGQAAQGSSTGNSSFSVPRSAPSPIAPSLTRRDIASPLVPPTPRCASCSPHSHLGRPRVMAEVPNLAQTSGGNWRQCPGAPPVRPVSWRWGSGLGYQHS", "length": 231 }, "evidence": [ { "id": "G3N0S4", "url": "https://omabrowser.org/oma/group/G3N0S4/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q7RTU4-1", "protein_name": "Class A basic helix-loop-helix protein 9", "gene_name": "BHLHA9", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MLRGAPGLGLTARKGAEDSAEDLGGPCPEPGGDSGVLGANGASCSRGEAEEPAGRRRARPVRSKARRMAANVRERKRILDYNEAFNALRRALRHDLGGKRLSKIATLRRAIHRIAALSLVLRASPAPRGPCGHLECHGPAARGDTGDTGASPPPPAGPSLARPDAARPSVPSAPRCASCPPHAPLARPSAVAEGPGLAQASGGSWRRCPGASSAGPPPWPRGYLRSAPGMGHPRS", "length": 235 }, "evidence": [ { "id": "G3N0S4", "url": "https://omabrowser.org/oma/group/G3N0S4/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" } ], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 1, "go_terms": [ { "name": "cytoplasm", "id": "GO:0005737", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005737", "evidence": [ { "database": "UniProtKB", "id": "G3N0S4", "url": "https://www.uniprot.org/uniprotkb/G3N0S4" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 3, "go_terms": [ { "name": "DNA-templated transcription", "id": "GO:0006351", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006351", "evidence": [ { "database": "UniProtKB", "id": "G3N0S4", "url": "https://www.uniprot.org/uniprotkb/G3N0S4" } ], "pmid": "" }, { "name": "regulation of transcription by RNA polymerase II", "id": "GO:0006357", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006357", "evidence": [ { "database": "UniProtKB", "id": "G3N0S4", "url": "https://www.uniprot.org/uniprotkb/G3N0S4" } ], "pmid": "" }, { "name": "developmental process", "id": "GO:0032502", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0032502", "evidence": [ { "database": "UniProtKB", "id": "G3N0S4", "url": "https://www.uniprot.org/uniprotkb/G3N0S4" } ], "pmid": "" } ] }, { "name": "Molecular Function", "total": 3, "go_terms": [ { "name": "protein heterodimerization activity", "id": "GO:0046982", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0046982", "evidence": [ { "database": "UniProtKB", "id": "G3N0S4", "url": "https://www.uniprot.org/uniprotkb/G3N0S4" } ], "pmid": "" }, { "name": "RNA polymerase II transcription regulatory region sequence-specific DNA binding", "id": "GO:0000977", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000977", "evidence": [ { "database": "UniProtKB", "id": "G3N0S4", "url": "https://www.uniprot.org/uniprotkb/G3N0S4" } ], "pmid": "" }, { "name": "DNA-binding transcription factor activity, RNA polymerase II-specific", "id": "GO:0000981", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000981", "evidence": [ { "database": "UniProtKB", "id": "G3N0S4", "url": "https://www.uniprot.org/uniprotkb/G3N0S4" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "G3N0S4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3N0S4" }, { "id": "PS50888", "database": "PROSITE", "url": "https://prosite.expasy.org/PS50888" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "BHLH", "eco_id": "ECO_0000259", "start_pos": 66, "end_pos": 118, "start_aa": "Ala", "end_aa": "Leu", "glycosite_overlap": [] } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "homologset.oma", "label": "OMA Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { 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"total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ], "tool_support": { "graph_view": "yes" } }, { "uniprot_canonical_ac": "G3N0S9-1", "uniprot_ac": "G3N0S9", "uniprot_id": "G3N0S9_BOVIN", "mass": { "chemical_mass": 21488.0, "monoisotopic_mass": 21488.0 }, "refseq": {}, "gene_names": [], "protein_names": [ { "name": "Sushi domain-containing protein", "type": "recommended", "evidence": [ { "id": "G3N0S9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3N0S9/entry#names_and_taxonomy" } ] } ], "function": [], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Bos taurus", "taxid": 9913, "evidence": [ { "database": "UniProtKB", "id": "G3N0S9", "url": "https://www.uniprot.org/uniprotkb/G3N0S9" } ], "common_name": "Bovine", "glygen_name": "Bovine", "reference_species": "Bos taurus [9913]" } ], "gene": [ { "name": "", "url": "https://www.uniprot.org/uniprotkb/G3N0S9", "locus": {} } ], "crossref": [ { "id": "G3N0S9", "url": "https://alphafold.ebi.ac.uk/entry/G3N0S9", "database": "AlphaFoldDB", "categories": [] }, { "id": "ENSBTAG00000047621", "url": "https://bgee.org/?page=gene&gene_id=ENSBTAG00000047621", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "cd00033", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd00033", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "IPR000436", "url": "https://www.ebi.ac.uk/interpro/entry/IPR000436", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR035976", "url": "https://www.ebi.ac.uk/interpro/entry/IPR035976", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR040514", "url": "https://www.ebi.ac.uk/interpro/entry/IPR040514", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR051503", "url": "https://www.ebi.ac.uk/interpro/entry/IPR051503", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "ITCRNSR", "url": "https://omabrowser.org/oma/group/ITCRNSR/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "PTHR45785", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR45785", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR45785:SF2", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR45785:SF2", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00084", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00084", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF18453", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF18453", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "G3N0S9", "url": "https://www.uniprot.org/uniprotkb/G3N0S9", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "G3N0S9-1", "url": "https://www.uniprot.org/uniprotkb/G3N0S9-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MVCVEQNCPDSVPPLCDLGKVTVLLCCSPPPEVKHGHFVYIQREIWGTDVVEYECQEGYTLVGEARISCRFVGWSPPAPQCKALCQKPEISNGKLSVEKDQYVSPETVTVRCDPGYRMVGSQDILCSENKFWSPDVPKCEKVSAEVCEAVFKGQKLLKCLPNAMEAKVALELHKLSLEIEKLEQEKRKLEIA", "length": 192, "header": "tr|G3N0S9-1|G3N0S9_BOVIN Isoform 1 of Sushi domain-containing protein OS=Bos taurus OX=9913 GN= PE=4 SV=2 CANONICAL=G3N0S9-1" }, "isoforms": [ { "isoform_ac": "G3N0S9-1", "url": "https://www.uniprot.org/uniprotkb/G3N0S9/entry", "sequence": { "sequence": 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The olfactory receptor proteins are members of a large family of G-protein-coupled receptors (GPCR) arising from single coding-exon genes. Olfactory receptors share a 7-transmembrane domain structure with many neurotransmitter and hormone receptors and are responsible for the recognition and G protein-mediated transduction of odorant signals. The olfactory receptor gene family is the largest in the genome. [provided by RefSeq, Jul 2008].", "evidence": [ { "database": "RefSeq", "id": "NP_001377517", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001377517" } ] }, { "annotation": "Putative odorant or sperm cell receptor.", "evidence": [ { "database": "UniProtKB", "id": "G3N115", "url": "https://www.uniprot.org/uniprotkb/G3N115#function" }, { "database": "UniProtKB", "id": "ARBA00003929", "url": "https://www.uniprot.org/uniprotkb/ARBA00003929#function" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Bos taurus", "taxid": 9913, "evidence": [ { "database": "UniProtKB", "id": "G3N115", "url": "https://www.uniprot.org/uniprotkb/G3N115" } ], "common_name": "Bovine", "glygen_name": "Bovine", "reference_species": "Bos taurus [9913]" } ], "gene": [ { "name": "OR10V1", "url": "https://www.uniprot.org/uniprotkb/G3N115", "locus": { "chromosome": "15", "start_pos": 82907742, "end_pos": 82908671, "strand": "+", "evidence": [ { "database": "Ensembl Gene", "id": "ENSBTAG00000047472", "url": "https://www.ensembl.org/id/ENSBTAG00000047472" } ] } } ], "crossref": [ { "id": "G3N115", "url": "https://alphafold.ebi.ac.uk/entry/G3N115", "database": "AlphaFoldDB", "categories": [] }, { "id": "cd15225", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd15225", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "788711", "url": "https://www.ncbi.nlm.nih.gov/gene/788711", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR000276", "url": "https://www.ebi.ac.uk/interpro/entry/IPR000276", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR000725", "url": "https://www.ebi.ac.uk/interpro/entry/IPR000725", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR017452", "url": "https://www.ebi.ac.uk/interpro/entry/IPR017452", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": 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"database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MVDLFQGTWKSISCENFEEYMKELGIGRASRKLGCLAKPTVTIMTKEDLITIKTKSIFKNNDISFKLGEEFEETTPGGHKTKSTVILDDDSLVQVQDWDGKEITIRRKLVDEKMVVESVVNNVTCTRTYERVQTNPVSNS", "length": 140, "header": "tr|G3N125-1|G3N125_BOVIN Isoform 1 of Fatty acid binding protein 12 OS=Bos taurus OX=9913 GN=FABP12 PE=3 SV=1 CANONICAL=G3N125-1" }, "isoforms": [ { "isoform_ac": "G3N125-1", "url": "https://www.uniprot.org/uniprotkb/G3N125/entry", "sequence": { "sequence": "MVDLFQGTWKSISCENFEEYMKELGIGRASRKLGCLAKPTVTIMTKEDLITIKTKSIFKNNDISFKLGEEFEETTPGGHKTKSTVILDDDSLVQVQDWDGKEITIRRKLVDEKMVVESVVNNVTCTRTYERVQTNPVSNS", "length": 140, "header": "tr|G3N125-1|G3N125_BOVIN Isoform 1 of Fatty acid binding protein 12 OS=Bos taurus OX=9913 GN=FABP12 PE=3 SV=1 CANONICAL=G3N125-1" }, "locus": { "chromosome": "14", "start_pos": 44734289, "end_pos": 44726449, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000066006.3", "url": 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"id": "G3N125", "url": "https://omabrowser.org/oma/group/G3N125/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "Q9DAK4-1", "protein_name": "Fatty acid-binding protein 12", "gene_name": "Fabp12", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MVDQLQGTWKSVSCDNFENYMKELGVGRASRKLGCLAKPTVTISTDGDLITIKTKSIFKNKEISFKLGEEFEETTPSGRKSKSTVILDNDSLVQVQDWDGKEATICRRLVDGKMVVESAVNNVTCTRTYQRV", "length": 132 }, "evidence": [ { "id": "G3N125", "url": "https://omabrowser.org/oma/group/G3N125/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" } ], "go_annotation": { "categories": [ { "name": "Molecular Function", "total": 1, "go_terms": [ { "name": "fatty acid binding", "id": "GO:0005504", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005504", "evidence": [ { "database": "UniProtKB", "id": "G3N125", "url": "https://www.uniprot.org/uniprotkb/G3N125" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 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"table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ], "tool_support": { "graph_view": "yes" } }, { "uniprot_canonical_ac": "G3N133-1", "uniprot_ac": "G3N133", "uniprot_id": "G3N133_BOVIN", "mass": { "chemical_mass": 59652.0, "monoisotopic_mass": 59652.0 }, "refseq": { "ac": "XP_005207873", "name": "tigger transposable element-derived protein 2", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_005207873" }, "gene_names": [ { "name": "TIGD2", "type": "recommended", "evidence": [ { "id": "G3N133", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3N133" } ] }, { "name": "TIGD2", "type": "synonym", "evidence": [ { "id": "XP_005207873", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_005207873" } ] } ], "protein_names": [ { "name": "Tigger transposable element derived 2", "type": "synonym", "evidence": [ { "id": "G3N133", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3N133/entry#names_and_taxonomy" } ] }, { "name": "tigger transposable element-derived protein 2", "type": "synonym", "evidence": [ { "id": "XP_005207873", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_005207873" } ] } ], "function": [], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Bos taurus", "taxid": 9913, "evidence": [ { "database": "UniProtKB", "id": "G3N133", "url": "https://www.uniprot.org/uniprotkb/G3N133" } ], "common_name": "Bovine", "glygen_name": "Bovine", "reference_species": "Bos taurus [9913]" } ], "gene": [ { "name": "TIGD2", "url": "https://www.uniprot.org/uniprotkb/G3N133", "locus": { "chromosome": "6", "start_pos": 35690805, "end_pos": 35695110, "strand": "+", "evidence": [ { "database": "Ensembl Gene", "id": "ENSBTAG00000015265", "url": "https://www.ensembl.org/id/ENSBTAG00000015265" } ] } } ], "crossref": [ { "id": "G3N133", "url": "https://alphafold.ebi.ac.uk/entry/G3N133", "database": "AlphaFoldDB", "categories": [] }, { "id": "ENSBTAG00000015265", "url": "https://bgee.org/?page=gene&gene_id=ENSBTAG00000015265", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "101903701", "url": "https://www.ncbi.nlm.nih.gov/gene/101903701", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR004875", "url": "https://www.ebi.ac.uk/interpro/entry/IPR004875", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR006600", "url": "https://www.ebi.ac.uk/interpro/entry/IPR006600", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR007889", "url": "https://www.ebi.ac.uk/interpro/entry/IPR007889", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR009057", "url": "https://www.ebi.ac.uk/interpro/entry/IPR009057", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR050863", "url": "https://www.ebi.ac.uk/interpro/entry/IPR050863", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "bta:101903701", "url": "https://www.genome.jp/dbget-bin/www_bget?bta:101903701", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "QWFDSQS", "url": "https://omabrowser.org/oma/group/QWFDSQS/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "G3N133", "url": "https://www.orthodb.org/?gene=G3N133", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR19303", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR19303", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR19303:SF22", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR19303:SF22", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF03184", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF03184", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF03221", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF03221", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF04218", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF04218", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "XP_005207873", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_005207873", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "G3N133", "url": "https://www.uniprot.org/uniprotkb/G3N133", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "G3N133-1", "url": "https://www.uniprot.org/uniprotkb/G3N133-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MLGKRKRVVLTIKDKLDIIKKLEEGISFKKLSVVYGIGESTVRDIKKNKERIINYANSSDPTSGVSKRKSMKSSTYEELDRVMIEWFNQQKTDGIPVSGTICAKQAKFFFDALGMEGDFNASSGWLTRFKQRHGIPKAAGKGTKLKGDETAASEFCGNFQEFVERENLQPEQIYGADQTGLFWKCLPSRTLALETEQSSSGYRSSRERIIIMCCANATGLHKLNLCVVGKAKKPRAFKGADLSNLPVTYFSQKSAWIEHSVFRQWFEKYFVPQVQKHLKSKGLLEKAVLLLDFPPAHPNEELLSSDDGRIIVKYLPPNVTSLIQPMSQGVLATVKRYYRAGLLQKYMDEGTDPRMFWKNLTVLDAIYEVSRAWNMIKSSTITKAWKKLFPGTEENSGMNIDEGAILAANLATVLQNTEDCEHVDLENIDQWFDSRSNDSSCQVLTDSEGVEDQARPAETKPSSKTRKTELNPEKHISHKAALEWTENLLDYLEQQDDMLLSDKLVLRRLRTIIRRKQKIQNNKSH", "length": 525, "header": "tr|G3N133-1|G3N133_BOVIN Isoform 1 of Tigger transposable element derived 2 OS=Bos taurus OX=9913 GN=TIGD2 PE=4 SV=1 CANONICAL=G3N133-1" }, "isoforms": [ { "isoform_ac": "G3N133-1", "url": "https://www.uniprot.org/uniprotkb/G3N133/entry", "sequence": { "sequence": "MLGKRKRVVLTIKDKLDIIKKLEEGISFKKLSVVYGIGESTVRDIKKNKERIINYANSSDPTSGVSKRKSMKSSTYEELDRVMIEWFNQQKTDGIPVSGTICAKQAKFFFDALGMEGDFNASSGWLTRFKQRHGIPKAAGKGTKLKGDETAASEFCGNFQEFVERENLQPEQIYGADQTGLFWKCLPSRTLALETEQSSSGYRSSRERIIIMCCANATGLHKLNLCVVGKAKKPRAFKGADLSNLPVTYFSQKSAWIEHSVFRQWFEKYFVPQVQKHLKSKGLLEKAVLLLDFPPAHPNEELLSSDDGRIIVKYLPPNVTSLIQPMSQGVLATVKRYYRAGLLQKYMDEGTDPRMFWKNLTVLDAIYEVSRAWNMIKSSTITKAWKKLFPGTEENSGMNIDEGAILAANLATVLQNTEDCEHVDLENIDQWFDSRSNDSSCQVLTDSEGVEDQARPAETKPSSKTRKTELNPEKHISHKAALEWTENLLDYLEQQDDMLLSDKLVLRRLRTIIRRKQKIQNNKSH", "length": 525, "header": "tr|G3N133-1|G3N133_BOVIN Isoform 1 of Tigger transposable element derived 2 OS=Bos taurus OX=9913 GN=TIGD2 PE=4 SV=1 CANONICAL=G3N133-1" }, "locus": { "chromosome": "6", "start_pos": 35693638, "end_pos": 35692064, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000020304.7", "url": "https://www.ensembl.org/id/ENSBTAT00000020304.7" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000055555.1", "url": "https://www.ensembl.org/id/ENSBTAP00000055555.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [ { "id": "bta:101903701", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?bta:101903701", "resource": "KEGG Pathway" } ], "orthologs": [ { "uniprot_canonical_ac": "A0A287B330-1", "protein_name": "Tigger transposable element derived 2", "gene_name": "TIGD2", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MLGKRKRVVLTIKDKLDIIKKLEEGISFKKLSVVYGIGESTVRDIKKNKERIINYANSSDPTSGVSKRKSMKSSTYEELDRVMIEWFNQQKMEGIPVSGTICAKQAKFFFDALGMEGDFNASSGWLTRFKQRHGIPKAAGKGTKLKGDETAAREFCGNFQEFVERENLQPEQIYGADQTGLFWKCLPSRTLAFETEQSASGYRSSRERIIIMCCANATGLHKLNLCVVGKAKKPRAFKGADLSNLPVTYFSQKSAWIEHSVFRQWFEKYFVPQVQKHLKSKGLLEKAVLLLDFPPAHPDEELLRSDDGRIIVKYLPPNVTSLIQPMSQGVLATVKRYYRAGLLQKYMDEGIDPRMFWKNLTVLDAIYEVSRAWNMVKSSTITKAWKKLFPGSEESSGMNIDEGAILAANLATVLQNTEDCEHVDLETIDQWFDSRSNDSSCQVLTDSEGAEDPAKPAEHKPSSKTRRADLNPEKHISHKAALEWTENLLDYLEQQDDMLLSDKLVLRRLRTIIRRKQKIQNNKSR", "length": 525 }, "evidence": [ { "id": "G3N133", "url": "https://omabrowser.org/oma/group/G3N133/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "F1LVC4-1", "protein_name": "Tigger transposable element derived 2", "gene_name": "Tigd2", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MLGKRKRVVLTIKDKLDIIKKLEEGNSFKKLSVLYGIGESTVRDIKKNKERIINYANNSDPTSGVSKRKSMKSSTYEELDRVMIEWFNQQKTNGIPVSGTICAKQARFFFDALGMEGDFNASSGWLTRFKQRHGIPKAAGKGTKLKGDETAASEFCGNFQEFVKRENLLPEQIYGADQTGLFWKCLPTRTLAFDTDQSTCEYRTSRERIIIMCCANATGLHKLNLCVVGKAKRPRAFKGTDLSNLPVTYFSQKSAWIEPSVLKQWFEKCFVPQVQKHLKSKGLREKAVLLLDFPAAHPAEELLNSDDGRIIVKYLPPNVTSLIQPMSQGVLTTVKRYYRAGLIQKYMDEGNDPKLFWKNLTVLDAIYEASRAWNQIRSSTITRAWRKLFPGNEENPSVSIDEGAILAANLATVLQNTEDCEHVNIENIGQWFDSRSSGSNCQVLADLVGAADRAKAGEQKQPSRKTRKAELNPEKHISHRAALEWTENLLDYLEQQDDMLLSDKLVLRRLRTIIRRKQRIQTKSHL", "length": 526 }, "evidence": [ { "id": "G3N133", "url": "https://omabrowser.org/oma/group/G3N133/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "G3I6M8-1", "protein_name": "Tigger transposable element-derived protein 2", "gene_name": "Tigd2", "tax_id": 10029, "organism": "Cricetulus griseus", "sequence": { "sequence": "MLGKRKRVVLTIKDKLDIIKKLEEGNSFKKLSVVYGIGESTVRDIKKNKERIINYANSSDPTSGVSKRKSMKSSTYEELDRVMIEWFNQQKTDGIPVSGTLCAKQAKFFFDALGMEGDFNASSGWLTRFKQRHGIPKAAGKGTKLKGDETAASEFCGSFQEFVERENLLPEQIYGADQTGLFWKCLPSRTLALDSDQSTSEYRSSRERIIIMCCANATGLHKLNLCVVGKAKRPRSFKGTDLSNLPVSYFSQKSAWIEQSVFKQWFEKCFVPQVQKHLNSKGLREKAVLLIDFPAARPAEDLLSSDDGRIVVKYLPPNVASLIQPMSQGVLTTVKRYYRAGLIQKYMDGGNDPKMFWKNLTVLDAIYEASRAWNMIRSNTITRAWKKLFPGNEENSSVSIDEGAILAANLATVLQNTEDCEHVDIENIEPWLDSRSSVSNCQVLADTAGAEKQAVTAEQKPSRKTRKAELHPEKHISHKAALEWTENLLDYLEQQDDMLLSDKLVLRRLRTIIRRKQRIQSKNHL", "length": 525 }, "evidence": [ { "id": "G3N133", "url": "https://omabrowser.org/oma/group/G3N133/", "database": "OMA" } ], "glygen_name": "Hamster", "common_name": "Chinese hamster" }, { "uniprot_canonical_ac": "Q0VBL1-1", "protein_name": "Tigger transposable element-derived protein 2", "gene_name": "Tigd2", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MLGKRKRVVLTIKDKLDIIKKLEEGNSFKKLSVLYGIGESTVRDIKKNKERIINYANSSDPTSGVSKRKSMKSSTYEELDRVMIEWFNQQKTDGIPVSGTICAKQARFFFDALGMEGDFNASSGWLTRFKQRHGIPKAAGKGTKLKGDETAASEFCGNFQEFVERENLLPEQIYGADQTGLFWKCLPTRTLAFDTDQSTCEYRTSRERIIIMCCANATGSHKLNLCVVGKAKRPRAFKGTDLSNLPVTYFSQKSAWIEPSVLKQWFEKCFVPQVQKHLKSKGLREKAVLLLDFPAAHPAEELLSSDDGRIIVKYLPPNVTSLIQPMSQGVLTTVKRYYRAGLIQKYMDEGNDPKTFWKNLTVLDAIYEASRAWNQIRSNTITRAWKKLFPGNEENPSVSIDEGAILAANLATVLQNTEDCEHVNIENIEQWFDSRSSGSNCQVLADIVGAADRAKVTEQKPSRKTRKAELNPEKHISHKAALEWTENLLDYLEQQDDMLLSDKLVLRRLRTIIRRKQRIQNKSHL", "length": 525 }, "evidence": [ { "id": "G3N133", "url": "https://omabrowser.org/oma/group/G3N133/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q4W5G0-1", "protein_name": "Tigger transposable element-derived protein 2", "gene_name": "TIGD2", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MLGKRKRVVLTIKDKLDIIKKLEEGISFKKLSVVYGIGESTVRDIKKNKERIINYANSSDPTSGVSKRKSMKSSTYEELDRVMIEWFNQQKTDGIPVSGTICAKQAKFFFDALGMEGDFNASSGWLTRFKQRHGIPKAAGKGTKLKGDETAAREFCGSFQEFVEKENLQPEQIYGADQTGLFWKCLPSRTLTLETDQSTSGCRSSRERIIIMCCANATGLHKLNLCVVGKAKKPRAFKGTDLSNLPVTYYSQKGAWIEQSVFRQWFEKYFVPQVQKHLKSKGLLEKAVLLLDFPPARPNEEMLSSDDGRIIVKYLPPNVTSLIQPMSQGVLATVKRYYRAGLLQKYMDEGNDPKIFWKNLTVLDAIYEVSRAWNMVKSSTITKAWKKLFPGNEENSGMNIDEGAILAANLATVLQNTEECEHVDIENIDQWFDSRSSDSSCQVLTDSESAEDQTKAAEQKPSSKSRKTELNPEKHISHKAALEWTENLLDYLEQQDDMLLSDKLVLRRLRTIIRKKQKIQNNKNH", "length": 525 }, "evidence": [ { "id": "G3N133", "url": "https://omabrowser.org/oma/group/G3N133/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" } ], "go_annotation": { "categories": [ { "name": "Molecular Function", "total": 1, "go_terms": [ { "name": "DNA binding", "id": "GO:0003677", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003677", "evidence": [ { "database": "UniProtKB", "id": "G3N133", "url": "https://www.uniprot.org/uniprotkb/G3N133" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 1, "go_terms": [ { "name": "nucleus", "id": "GO:0005634", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005634", "evidence": [ { "database": "UniProtKB", "id": "G3N133", "url": "https://www.uniprot.org/uniprotkb/G3N133" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 120, "end_pos": 122, "annotation": "n_glycosylation_sequon" }, { "start_pos": 216, "end_pos": 218, "annotation": "n_glycosylation_sequon" }, { "start_pos": 318, "end_pos": 320, "annotation": "n_glycosylation_sequon" }, { "start_pos": 359, "end_pos": 361, "annotation": "n_glycosylation_sequon" }, { "start_pos": 437, "end_pos": 439, "annotation": "n_glycosylation_sequon" }, { "start_pos": 522, "end_pos": 524, "annotation": "n_glycosylation_sequon" }, { "start_pos": 57, "end_pos": 59, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [ { "pdb_id": "AF-G3N133-F1", "pdb_chain": "global", "start_pos": 1, "end_pos": 525, "overlap": "1.0", "method": "AlphaFold", "type": "alphafold", "resolution": -1.0, "url": "https://data.glygen.org/ln2downloads/pdb/current/AF-G3N133-F1.pdb", "url_external": "https://alphafold.ebi.ac.uk/entry/G3N133" } ], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "G3N133", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3N133" }, { "id": "PRU00320", "database": "PROSITE", "url": "https://prosite.expasy.org/PRU00320" } ], "ann_type": "Nucleotide_Binding_Annotation", "uniprotkb_annotation": "H-T-H motif", "eco_id": "ECO_0000256", "start_pos": 28, "end_pos": 48, "start_aa": "Phe", "end_aa": "Asn", "glycosite_overlap": [] }, { "evidence": [ { "id": "G3N133", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3N133" }, { "id": "PS51253", "database": "PROSITE", "url": "https://prosite.expasy.org/PS51253" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "HTH CENPB-type", "eco_id": "ECO_0000259", "start_pos": 67, "end_pos": 139, "start_aa": "Lys", "end_aa": "Ala", "glycosite_overlap": [] }, { "evidence": [ { "id": "G3N133", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3N133" }, { "id": "PS50960", "database": "PROSITE", "url": "https://prosite.expasy.org/PS50960" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "HTH psq-type", "eco_id": "ECO_0000259", "start_pos": 1, "end_pos": 52, "start_aa": "Met", "end_aa": "Ile", "glycosite_overlap": [] } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "homologset.oma", "label": "OMA Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 120, "end_pos": 122 }, { "start_pos": 216, "end_pos": 218 }, { "start_pos": 318, "end_pos": 320 }, { "start_pos": 359, "end_pos": 361 }, { "start_pos": 437, "end_pos": 439 }, { "start_pos": 522, "end_pos": 524 }, { "start_pos": 57, "end_pos": 59 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { 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"n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ], "tool_support": { "graph_view": "yes" } }, { "uniprot_canonical_ac": "G3N134-1", "uniprot_ac": "G3N134", "uniprot_id": "G3N134_BOVIN", "mass": { "chemical_mass": 11973.0, "monoisotopic_mass": 11973.0 }, "refseq": {}, "gene_names": [], "protein_names": [ { "name": "Ig-like domain-containing protein", "type": "recommended", "evidence": [ { "id": "G3N134", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3N134/entry#names_and_taxonomy" } ] } ], "function": [], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Bos taurus", "taxid": 9913, "evidence": [ { "database": "UniProtKB", "id": "G3N134", "url": "https://www.uniprot.org/uniprotkb/G3N134" } ], "common_name": "Bovine", "glygen_name": "Bovine", "reference_species": "Bos taurus [9913]" } ], "gene": [ { "name": "", "url": "https://www.uniprot.org/uniprotkb/G3N134", "locus": {} } ], "crossref": [ { "id": "G3N134", "url": "https://alphafold.ebi.ac.uk/entry/G3N134", "database": "AlphaFoldDB", "categories": [] }, { "id": "ENSBTAG00000046584", "url": "https://bgee.org/?page=gene&gene_id=ENSBTAG00000046584", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "IPR007110", "url": "https://www.ebi.ac.uk/interpro/entry/IPR007110", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR013106", "url": "https://www.ebi.ac.uk/interpro/entry/IPR013106", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR013783", "url": "https://www.ebi.ac.uk/interpro/entry/IPR013783", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR036179", "url": "https://www.ebi.ac.uk/interpro/entry/IPR036179", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR050150", "url": "https://www.ebi.ac.uk/interpro/entry/IPR050150", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "YCAVWPS", "url": "https://omabrowser.org/oma/group/YCAVWPS/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "PTHR23267", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR23267", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF07686", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF07686", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "G3N134", "url": "https://www.uniprot.org/uniprotkb/G3N134", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "G3N134-1", "url": "https://www.uniprot.org/uniprotkb/G3N134-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "QPVLTEPASPSAYPGASARLTCTLSSGYRVGGYQMSCFQQKAGSPPWYLLMFKSDSDKPQGSGVPSHFSGSKAASANTGLLLISGLQTQDEADYNCYCPRNTGIYQVPRTAQG", "length": 113, "header": "tr|G3N134-1|G3N134_BOVIN Isoform 1 of Ig-like domain-containing protein OS=Bos taurus OX=9913 GN= PE=4 SV=3 CANONICAL=G3N134-1" }, "isoforms": [ { "isoform_ac": "G3N134-1", "url": "https://www.uniprot.org/uniprotkb/G3N134/entry", "sequence": { "sequence": "QPVLTEPASPSAYPGASARLTCTLSSGYRVGGYQMSCFQQKAGSPPWYLLMFKSDSDKPQGSGVPSHFSGSKAASANTGLLLISGLQTQDEADYNCYCPRNTGIYQVPRTAQG", "length": 113, "header": "tr|G3N134-1|G3N134_BOVIN Isoform 1 of Ig-like domain-containing protein OS=Bos taurus OX=9913 GN= PE=4 SV=3 CANONICAL=G3N134-1" }, "locus": { "chromosome": "17", "start_pos": 70676082, "end_pos": 70675744, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000065768.3", "url": "https://www.ensembl.org/id/ENSBTAT00000065768.3" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000055556.3", "url": "https://www.ensembl.org/id/ENSBTAP00000055556.3" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [], "orthologs": [], "go_annotation": { "categories": [ { "name": "Biological Process", "total": 1, "go_terms": [ { "name": "immune response", "id": "GO:0006955", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006955", "evidence": [ { "database": "UniProtKB", "id": "G3N134", "url": "https://www.uniprot.org/uniprotkb/G3N134" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 1, "go_terms": [ { "name": "immunoglobulin complex", "id": "GO:0019814", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0019814", "evidence": [ { "database": "UniProtKB", "id": "G3N134", "url": "https://www.uniprot.org/uniprotkb/G3N134" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], 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"https://www.uniprot.org/uniprotkb/G3N148" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [ { "pdb_id": "AF-G3N148-F1", "pdb_chain": "global", "start_pos": 1, "end_pos": 117, "overlap": "1.0", "method": "AlphaFold", "type": "alphafold", "resolution": -1.0, "url": "https://data.glygen.org/ln2downloads/pdb/current/AF-G3N148-F1.pdb", "url_external": "https://alphafold.ebi.ac.uk/entry/G3N148" } ], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "G3N148", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3N148" }, { "id": "PS50835", "database": "PROSITE", "url": "https://prosite.expasy.org/PS50835" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "Ig-like", "eco_id": "ECO_0000259", "start_pos": 14, "end_pos": 117, "start_aa": "Pro", "end_aa": "Asp", "glycosite_overlap": [] } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "homologset.oma", "label": "OMA Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": 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{ "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ], "tool_support": { "graph_view": "yes" } }, { "uniprot_canonical_ac": "G3N174-1", "uniprot_ac": "G3N174", "uniprot_id": "G3N174_BOVIN", "mass": { "chemical_mass": 23933.0, "monoisotopic_mass": 23933.0 }, "refseq": { "ac": "XP_005225712", "name": "GSK-3-binding protein FRAT2", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_005225712" }, "gene_names": [ { "name": "FRAT2", "type": "recommended", "evidence": [ { "id": "G3N174", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3N174" } ] }, { "name": "FRAT2", "type": "synonym", "evidence": [ { "id": "XP_005225712", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_005225712" } ] } ], "protein_names": [ { "name": "FRAT regulator of WNT signaling pathway 2", "type": "synonym", "evidence": [ { "id": "G3N174", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3N174/entry#names_and_taxonomy" } ] }, { "name": "GSK-3-binding protein FRAT2", "type": "synonym", "evidence": [ { "id": "XP_005225712", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_005225712" } ] } ], "function": [], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Bos taurus", "taxid": 9913, "evidence": [ { "database": "UniProtKB", "id": "G3N174", "url": "https://www.uniprot.org/uniprotkb/G3N174" } ], "common_name": "Bovine", "glygen_name": "Bovine", "reference_species": "Bos taurus [9913]" } ], "gene": [ { "name": "FRAT2", "url": "https://www.uniprot.org/uniprotkb/G3N174", "locus": { "chromosome": "26", "start_pos": 18576256, "end_pos": 18578993, "strand": "+", "evidence": [ { "database": "Ensembl Gene", "id": "ENSBTAG00000046701", "url": "https://www.ensembl.org/id/ENSBTAG00000046701" } ] } } ], "crossref": [ { "id": "ENSBTAG00000046701", "url": "https://bgee.org/?page=gene&gene_id=ENSBTAG00000046701", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "539144", "url": "https://www.ncbi.nlm.nih.gov/gene/539144", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR008014", "url": "https://www.ebi.ac.uk/interpro/entry/IPR008014", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "bta:539144", "url": "https://www.genome.jp/dbget-bin/www_bget?bta:539144", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "PWNKKRI", "url": "https://omabrowser.org/oma/group/PWNKKRI/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "G3N174", "url": "https://www.orthodb.org/?gene=G3N174", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR35154", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR35154", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR35154:SF2", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR35154:SF2", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF05350", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF05350", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "R-BTA-196299", "url": "https://www.reactome.org/PathwayBrowser/#R-BTA-196299", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "R-BTA-4641262", "url": "https://www.reactome.org/PathwayBrowser/#R-BTA-4641262", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "XP_005225712", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_005225712", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "G3N174", "url": "https://www.uniprot.org/uniprotkb/G3N174", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "G3N174-1", "url": "https://www.uniprot.org/uniprotkb/G3N174-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MPCRREEEEEAGEEEEEEEDSILLLEQSVTVGGSVEVDRLVAQIGETLQLDAAQDRPASACAPPGPPLQPPRPPAAVRADKARAPAQPLLLPAVSVEAGGPAPSGALRCALGDRGRVRGRAAPYFVAELATGASTLPGPCRRGWLRGAVTSRRLPQRRWPPAGARANDDDPHRLLQQLVLSGNLIKEAVRRLQRAVAAVAATGPAGPAGPGASRSRPDPVSLQPSGALH", "length": 229, "header": "tr|G3N174-1|G3N174_BOVIN Isoform 1 of FRAT regulator of WNT signaling pathway 2 OS=Bos taurus OX=9913 GN=FRAT2 PE=3 SV=1 CANONICAL=G3N174-1" }, "isoforms": [ { "isoform_ac": "G3N174-1", "url": "https://www.uniprot.org/uniprotkb/G3N174/entry", "sequence": { "sequence": 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"id": "R-BTA-196299", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-BTA-196299", "resource": "Reactome", "description": "Beta-catenin phosphorylation cascade" }, { "id": "R-BTA-4641262", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-BTA-4641262", "resource": "Reactome", "description": "Disassembly of the destruction complex and recruitment of AXIN to the membrane" } ], "orthologs": [ { "uniprot_canonical_ac": "A0A287BA44-1", "protein_name": "FRAT regulator of WNT signaling pathway 2", "gene_name": "FRAT2", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MPCWREEEVEAGEEEEEEDSFLLLEQSVTLGGSGEVDRLVAQIGETLQLDAAQDRPVSPCALPGPPLQPPRPPAAVLAEKARAPALPLLLPPGSAEARGPGPLGALRCPFGDRGRVRNRTAPYFVAELAAGPNALPGPCRRGWLRSAVASRRLQQRPWPPAGARANDDDPHRLLQQLVLSGNLIKEAVRRLQRAVAAVAATGPTGGPGAGSSCSRPDPVALQPSGALH", "length": 228 }, "evidence": [ { "id": "G3N174", "url": "https://omabrowser.org/oma/group/G3N174/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "M0R5Z2-1", "protein_name": "FRAT regulator of WNT signaling pathway 2", "gene_name": "Frat2", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MPCRREEEEEEAGDEAEGEEDDDSFLLLQQSVTLGGSTDVDRLIAQIGETLQLDAAHDSPASPCAAPGPPPAPPVLAALPADKVGGPARLLRPAASAEAGDPAPPGAVRCVLGERGRVRGRAAPYCVAEIAPGASALPRPGRRGWLPGALASRRIQQRRCTASGSRAADDDPHRLLQQLVLSGNLIKEAVRRLQRAVAAVAATSPASAPGSGGGRSGPDSVTLQPSGSWL", "length": 230 }, "evidence": [ { "id": "G3N174", "url": "https://omabrowser.org/oma/group/G3N174/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "O75474-1", "protein_name": "GSK-3-binding protein FRAT2", "gene_name": "FRAT2", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MPCRREEEEEAGEEAEGEEEEDDSFLLLQQSVTLGSSGEVDRLVAQIGETLQLDAAQDSPASPCAPPGVPLRAPGPLAAAVPADKARPPAVPLLLPPASAETVGPAPSGALRCALGDRGRVRGRAAPYCVAEVAAGPSALPGPCRRGWLRDAVTSRRLQQRRWTQAGARAGDDDPHRLLQQLVLSGNLIKEAVRRLQRAVAAVAATGPASAPGPGGGRSGPDRIALQPSGSLL", "length": 233 }, "evidence": [ { "id": "G3N174", "url": "https://omabrowser.org/oma/group/G3N174/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "Q8K025-1", "protein_name": "GSK-3-binding protein FRAT2", "gene_name": "Frat2", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MPCRREEEEEAGDEAEGEEDDDSFLLLQQSVTLGGSTDVDRLIVQIGETLQLDTAHDRPASPCAAPGPPPAPPRVLAALSADKTGTPARRLLRPTGSAETGDPAPPGAVRCVLGERGRVRGRSAPYCVAEIAPGASALPGPGRRGWLPGSVASHRIQQRRWTAGGARAADDDPHRLLQQLVLSGNLIKEAVRRLQRAVAAVAATSPASAPGSGGGRSGPDSVTLQPSGAWL", "length": 231 }, "evidence": [ { "id": "G3N174", "url": "https://omabrowser.org/oma/group/G3N174/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" } ], 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The olfactory receptor proteins are members of a large family of G-protein-coupled receptors (GPCR) arising from single coding-exon genes. Olfactory receptors share a 7-transmembrane domain structure with many neurotransmitter and hormone receptors and are responsible for the recognition and G protein-mediated transduction of odorant signals. The olfactory receptor gene family is the largest in the genome. [provided by RefSeq, Jul 2008].", "evidence": [ { "database": "RefSeq", "id": "NP_001377460", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001377460" } ] }, { "annotation": "Putative odorant or sperm cell receptor.", "evidence": [ { "database": "UniProtKB", "id": "G3N1H7", "url": "https://www.uniprot.org/uniprotkb/G3N1H7#function" }, { "database": "UniProtKB", "id": "ARBA00003929", "url": "https://www.uniprot.org/uniprotkb/ARBA00003929#function" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Bos taurus", "taxid": 9913, "evidence": [ { "database": "UniProtKB", "id": "G3N1H7", "url": "https://www.uniprot.org/uniprotkb/G3N1H7" } ], "common_name": "Bovine", "glygen_name": "Bovine", "reference_species": "Bos taurus [9913]" } ], "gene": [ { "name": "OR52AC1", "url": "https://www.uniprot.org/uniprotkb/G3N1H7", "locus": { "chromosome": "15", "start_pos": 47606948, "end_pos": 47607937, "strand": "+", 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"common_name": "Rat" }, { "uniprot_canonical_ac": "I3L5R4-1", "protein_name": "Four-jointed box kinase 1", "gene_name": "FJX1", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MGWRMRGAAATAGLWLLALGSLLALWGGLLPPRTELPASQTPKDRLPRRPARSGGREPAPRFPLPPPLARDARGGSLKTFRVLLTLAASSDGPPGQPPGERRRHVPTGRSWPEERAAVHGGVFWSRGLEEQVPPGFSEAQAAAWLEAARSARVVALERGGCGRSSNRLARFADGTRACVRYGINPEQIQGEALSYYLARLLGLQRHVPPLALARVEARGAQWAQVQEELRAAHWTEGSVVSLTRWLPNLTDVVVPAPWRSEDGHLRPLRAVGAELANRSQAELVDLVQWTDLILFDYLTANFDRLVSNLFSLQWDPRVMQRATSNLHRGPGGALVFLDNEAGLVHGYRVAGMWDKYNEPLLQSVCVFRERTARRVLELHRGRDAAARLLRLYQHHEPHFPELAALADPHAQLLQRRLDFLAKHILHCKAKYGRRPGT", "length": 437 }, "evidence": [ { "id": "G3N1N8", "url": "https://omabrowser.org/oma/group/G3N1N8/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "Q86VR8-1", "protein_name": "Four-jointed box protein 1", "gene_name": "FJX1", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": 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"Cellular Component", "total": 1, "go_terms": [ { "name": "extracellular space", "id": "GO:0005615", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005615", "evidence": [ { "database": "UniProtKB", "id": "G3N1N8", "url": "https://www.uniprot.org/uniprotkb/G3N1N8" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 1, "go_terms": [ { "name": "cell-cell signaling", "id": "GO:0007267", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007267", "evidence": [ { "database": "UniProtKB", "id": "G3N1N8", "url": "https://www.uniprot.org/uniprotkb/G3N1N8" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 248, "end_pos": 250, "annotation": "n_glycosylation_sequon" }, { "start_pos": 277, "end_pos": 279, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [ { "pdb_id": "AF-G3N1N8-F1", "pdb_chain": "global", "start_pos": 1, "end_pos": 437, "overlap": "1.0", "method": "AlphaFold", "type": "alphafold", "resolution": -1.0, "url": "https://data.glygen.org/ln2downloads/pdb/current/AF-G3N1N8-F1.pdb", "url_external": "https://alphafold.ebi.ac.uk/entry/G3N1N8" } ], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "G3N1N8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3N1N8" }, { "id": "PF28411", "database": "Pfam", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF28411" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "Four-jointed box protein middle", "eco_id": "ECO_0000259", "start_pos": 140, "end_pos": 249, "start_aa": "Gln", "end_aa": "Leu", "glycosite_overlap": [] } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "homologset.oma", "label": "OMA Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], 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"id": "G3N1Q7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3N1Q7/entry#names_and_taxonomy" } ] }, { "name": "sperm axonemal maintenance protein CFAP97D1 isoform X1", "type": "synonym", "evidence": [ { "id": "XP_059734537", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_059734537" } ] } ], "function": [], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Bos taurus", "taxid": 9913, "evidence": [ { "database": "UniProtKB", "id": "G3N1Q7", "url": "https://www.uniprot.org/uniprotkb/G3N1Q7" } ], "common_name": "Bovine", "glygen_name": "Bovine", "reference_species": "Bos taurus [9913]" } ], "gene": [ { "name": "CFAP97D1", "url": "https://www.uniprot.org/uniprotkb/G3N1Q7", "locus": { "chromosome": "19", "start_pos": 43676150, "end_pos": 43671643, "strand": "-", "evidence": [ { "database": "Ensembl Gene", "id": "ENSBTAG00000045732", "url": "https://www.ensembl.org/id/ENSBTAG00000045732" } ] } } ], "crossref": [ { "id": "G3N1Q7", "url": "https://alphafold.ebi.ac.uk/entry/G3N1Q7", "database": "AlphaFoldDB", "categories": [] }, { "id": "ENSBTAG00000045732", "url": "https://bgee.org/?page=gene&gene_id=ENSBTAG00000045732", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "100296376", "url": "https://www.ncbi.nlm.nih.gov/gene/100296376", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "8OTZ", "url": "https://www.ncbi.nlm.nih.gov/Structure/icn3d/?mmdbid=8OTZ&bu=0", "database": "iCn3D", "categories": [ "3D Structure" ] }, { "id": "9FQR", "url": "https://www.ncbi.nlm.nih.gov/Structure/icn3d/?mmdbid=9FQR&bu=0", "database": "iCn3D", "categories": [ "3D Structure" ] }, { "id": "IPR029488", "url": "https://www.ebi.ac.uk/interpro/entry/IPR029488", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR038792", "url": "https://www.ebi.ac.uk/interpro/entry/IPR038792", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "bta:100296376", "url": "https://www.genome.jp/dbget-bin/www_bget?bta:100296376", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "DHVQWEE", "url": "https://omabrowser.org/oma/group/DHVQWEE/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "G3N1Q7", "url": "https://www.orthodb.org/?gene=G3N1Q7", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR33768", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR33768", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR33768:SF5", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR33768:SF5", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "pdb_00008otz", "url": "https://www.rcsb.org/structure/pdb_00008otz", "database": "PDB", "categories": [ "3D Structure" ] }, { "id": "pdb_00009fqr", "url": "https://www.rcsb.org/structure/pdb_00009fqr", "database": "PDB", "categories": [ "3D Structure" ] }, { "id": "8OTZ", "url": "https://www.rcsb.org/structure/8OTZ", "database": "PDB", "categories": [ "3D Structure" ] }, { "id": "9FQR", "url": "https://www.rcsb.org/structure/9FQR", "database": "PDB", "categories": [ "3D Structure" ] }, { "id": "PF13879", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF13879", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "XP_059734537", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_059734537", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0AAA9TY30", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TY30", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0AAA9TY30-1", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TY30-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "G3N1Q7", "url": "https://www.uniprot.org/uniprotkb/G3N1Q7", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "G3N1Q7-1", "url": "https://www.uniprot.org/uniprotkb/G3N1Q7-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MNNSLDYLAYPVIVSNHRQSTSFRKKLDFGHYAFHKNRIQIVKPTVDTKPPAAHTHHILKLSKLQGEQKRIDKIEYENKQLCQKIANAHRGPAKVDCWNEYFSKSLNRETRNRELVRITVENQGILKRLGDRKPHYDRKSSELDWQNSRRYIRNTTRYLLSRDK", "length": 164, "header": "tr|G3N1Q7-1|G3N1Q7_BOVIN Isoform 1 of CFAP97 domain containing 1 OS=Bos taurus OX=9913 GN=CFAP97D1 PE=1 SV=1 CANONICAL=G3N1Q7-1" }, "isoforms": [ { "isoform_ac": "A0AAA9TY30-1", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TY30/entry", "sequence": { "sequence": "MAAAGPCTPGQPRARGERPGQLGGGSGAGTRPVPPWRRARKAREAAKRGRPGALSSVKPTVDTKPPAAHTHHILKLSKLQGEQKRIDKIEYENKQLCQKIANAHRGPAKVDCWNEYFSKSLNRETRNRELVRITVENQGILKRLGDRKPHYDRKSSELDWQNSRRYIRNTTRYLLSRDK", "length": 179, "header": "tr|A0AAA9TY30-1|A0AAA9TY30_BOVIN Computationally mapped isoform of CFAP97 domain containing 1 OS=Bos taurus OX=9913 GN=CFAP97D1 PE=3 SV=1 CANONICAL=G3N1Q7-1" }, "locus": { "chromosome": "19", "start_pos": 43676147, "end_pos": 43671841, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000111098.1", "url": "https://www.ensembl.org/id/ENSBTAT00000111098.1" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000103267.1", "url": "https://www.ensembl.org/id/ENSBTAP00000103267.1" } ] } }, { "isoform_ac": "G3N1Q7-1", "url": "https://www.uniprot.org/uniprotkb/G3N1Q7/entry", "sequence": { "sequence": "MNNSLDYLAYPVIVSNHRQSTSFRKKLDFGHYAFHKNRIQIVKPTVDTKPPAAHTHHILKLSKLQGEQKRIDKIEYENKQLCQKIANAHRGPAKVDCWNEYFSKSLNRETRNRELVRITVENQGILKRLGDRKPHYDRKSSELDWQNSRRYIRNTTRYLLSRDK", "length": 164, "header": "tr|G3N1Q7-1|G3N1Q7_BOVIN Isoform 1 of CFAP97 domain containing 1 OS=Bos taurus OX=9913 GN=CFAP97D1 PE=1 SV=1 CANONICAL=G3N1Q7-1" }, "locus": { "chromosome": "19", "start_pos": 43676147, "end_pos": 43673408, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000065517.2", "url": 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"table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": 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"sort_fields": [] } ], "tool_support": { "graph_view": "yes" } }, { "uniprot_canonical_ac": "G3N1T9-1", "uniprot_ac": "G3N1T9", "uniprot_id": "G3N1T9_BOVIN", "mass": { "chemical_mass": 59579.0, "monoisotopic_mass": 59579.0 }, "refseq": { "ac": "XP_002694852", "name": "pyruvate dehydrogenase [acetyl-transferring]-phosphatase 2, mitochondrial", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_002694852" }, "gene_names": [ { "name": "PDP2", "type": "recommended", "evidence": [ { "id": "G3N1T9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3N1T9" } ] }, { "name": "PDP2", "type": "synonym", "evidence": [ { "id": "XP_002694852", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_002694852" } ] } ], "protein_names": [ { "name": "[Pyruvate dehydrogenase [acetyl-transferring]]-phosphatase 2, mitochondrial", "type": "recommended", "evidence": [ { "id": "G3N1T9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3N1T9/entry#names_and_taxonomy" } ] }, { "name": "3.1.3.43", "type": "synonym", "evidence": [ { "id": "G3N1T9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3N1T9/entry#names_and_taxonomy" } ] }, { "name": "Pyruvate dehydrogenase phosphatase catalytic subunit 2", "type": "synonym", "evidence": [ { "id": "G3N1T9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3N1T9/entry#names_and_taxonomy" } ] }, { "name": "pyruvate dehydrogenase [acetyl-transferring]-phosphatase 2, mitochondrial", "type": "synonym", "evidence": [ { "id": "XP_002694852", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_002694852" } ] } ], "function": [ { "annotation": "Mitochondrial enzyme that catalyzes the dephosphorylation and concomitant reactivation of the alpha subunit of the E1 component of the pyruvate dehydrogenase complex (PDC), thereby stimulating the conversion of pyruvate into acetyl-CoA. Acts as a crucial regulator of T cell metabolism and function, with a particular focus on T-helper Th17.", "evidence": [ { "database": "UniProtKB", "id": "G3N1T9", "url": "https://www.uniprot.org/uniprotkb/G3N1T9#function" }, { "database": "UniProtKB", "id": "ARBA00054115", "url": "https://www.uniprot.org/uniprotkb/ARBA00054115#function" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Bos taurus", "taxid": 9913, "evidence": [ { "database": "UniProtKB", "id": "G3N1T9", "url": "https://www.uniprot.org/uniprotkb/G3N1T9" } ], "common_name": "Bovine", "glygen_name": "Bovine", "reference_species": "Bos taurus [9913]" } ], "gene": [ { "name": "PDP2", "url": "https://www.uniprot.org/uniprotkb/G3N1T9", "locus": { "chromosome": "18", "start_pos": 34595013, "end_pos": 34587592, "strand": "-", "evidence": [ { "database": "Ensembl Gene", "id": "ENSBTAG00000046708", "url": "https://www.ensembl.org/id/ENSBTAG00000046708" } ] } } ], "crossref": [ { "id": "ENSBTAG00000046708", "url": "https://bgee.org/?page=gene&gene_id=ENSBTAG00000046708", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "cd00143", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd00143", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "100299267", "url": "https://www.ncbi.nlm.nih.gov/gene/100299267", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR000222", "url": "https://www.ebi.ac.uk/interpro/entry/IPR000222", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR001932", "url": "https://www.ebi.ac.uk/interpro/entry/IPR001932", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR015655", "url": "https://www.ebi.ac.uk/interpro/entry/IPR015655", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR036457", "url": "https://www.ebi.ac.uk/interpro/entry/IPR036457", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "bta:100299267", "url": "https://www.genome.jp/dbget-bin/www_bget?bta:100299267", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "DHNAWNP", "url": "https://omabrowser.org/oma/group/DHNAWNP/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "G3N1T9", "url": "https://www.orthodb.org/?gene=G3N1T9", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR13832", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR13832", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR13832:SF343", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR13832:SF343", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00481", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00481", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "R-BTA-204174", "url": "https://www.reactome.org/PathwayBrowser/#R-BTA-204174", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "XP_002694852", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_002694852", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "12669", "url": "https://www.rhea-db.org/rhea/12669", "database": "Rhea", "categories": [ "Enzyme and Pathway" ] }, { "id": "G3N1T9", "url": "https://www.uniprot.org/uniprotkb/G3N1T9", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "G3N1T9-1", "url": "https://www.uniprot.org/uniprotkb/G3N1T9-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MSSTVSYWILSSARKTIATLQGGQRLYSRYASNRSKSKWRLCPQGQAILKDSATACGGIALQKAYRHTSTEEEDFHLQLSPEQVNEVLRAGESAHKILDLVSRAPDSVLRFESNQLAANSPVEDRGGIAACLQTNGLLFGIFDGHGGHACAQAVSERLFYYVAVSLMSQQTLEQMEEAMESMKPLLPILQWLKHPGDSIYKDVTSVHLDHLRVYWQELLNLHMEMGLSTEEALMYSFQRLDSDISLEIQAPLEDEMTRNLSLQVAFSGATACLAHVDGVHLHVANAGDCRAILGVQEDNGMWSCLPLTQDHNAWNPAELSRLKREHPESEDRTVIMENRLLGVLMPCRAFGDVQLKWSKELQRSVLERGFDTEALNIYQFTPPHYYTPPYLTARPEVTYHRLRPQDKFLVLASDGLWDVLGNEDVVRLVVEHLAEEGQHKPDLAQRPTNLGLMQSLLQQRKAQGLHAADQNAATRLIRYAIGNNEYGEMEPERLSAMLTLPEDLARMYRDDITVTVVYFNSDSIGASSKGS", "length": 531, "header": "tr|G3N1T9-1|G3N1T9_BOVIN Isoform 1 of [Pyruvate dehydrogenase [acetyl-transferring]]-phosphatase 2, mitochondrial OS=Bos taurus OX=9913 GN=PDP2 PE=3 SV=1 CANONICAL=G3N1T9-1" }, "isoforms": [ { "isoform_ac": "G3N1T9-1", "url": "https://www.uniprot.org/uniprotkb/G3N1T9/entry", "sequence": { "sequence": "MSSTVSYWILSSARKTIATLQGGQRLYSRYASNRSKSKWRLCPQGQAILKDSATACGGIALQKAYRHTSTEEEDFHLQLSPEQVNEVLRAGESAHKILDLVSRAPDSVLRFESNQLAANSPVEDRGGIAACLQTNGLLFGIFDGHGGHACAQAVSERLFYYVAVSLMSQQTLEQMEEAMESMKPLLPILQWLKHPGDSIYKDVTSVHLDHLRVYWQELLNLHMEMGLSTEEALMYSFQRLDSDISLEIQAPLEDEMTRNLSLQVAFSGATACLAHVDGVHLHVANAGDCRAILGVQEDNGMWSCLPLTQDHNAWNPAELSRLKREHPESEDRTVIMENRLLGVLMPCRAFGDVQLKWSKELQRSVLERGFDTEALNIYQFTPPHYYTPPYLTARPEVTYHRLRPQDKFLVLASDGLWDVLGNEDVVRLVVEHLAEEGQHKPDLAQRPTNLGLMQSLLQQRKAQGLHAADQNAATRLIRYAIGNNEYGEMEPERLSAMLTLPEDLARMYRDDITVTVVYFNSDSIGASSKGS", "length": 531, "header": "tr|G3N1T9-1|G3N1T9_BOVIN Isoform 1 of [Pyruvate dehydrogenase [acetyl-transferring]]-phosphatase 2, mitochondrial OS=Bos taurus OX=9913 GN=PDP2 PE=3 SV=1 CANONICAL=G3N1T9-1" }, "locus": { "chromosome": "18", "start_pos": 34591668, "end_pos": 34590076, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000063372.3", "url": "https://www.ensembl.org/id/ENSBTAT00000063372.3" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000055842.1", "url": "https://www.ensembl.org/id/ENSBTAP00000055842.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [ "enzyme" ], "publication": [], "pathway": [ { "id": "bta:100299267", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?bta:100299267", "resource": "KEGG Pathway" }, { "id": "R-BTA-204174", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-BTA-204174", "resource": "Reactome", "description": "Regulation of pyruvate dehydrogenase (PDH) complex" } ], "orthologs": [ { "uniprot_canonical_ac": "A0A287B2X3-1", "protein_name": "[Pyruvate dehydrogenase [acetyl-transferring]]-phosphatase 2, mitochondrial", "gene_name": "PDP2", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MSSTVSYWILSSARNGIATLQGGQRLYSRCASNRIKSKWRLFARGPATLKNNAPCDDGLALRKAYRHTSTEEEDFHLQLSPEQVNEVLRAGESAHKILDLVSRVPNSVLRFESNQLAANSPVEDRRGVAACLQTNGLMFGVFDGHGGHACAQAVSERLFYYVAVSLMSQQTLEQMEGAMESMKPLLPILQWLKHPGDSIYKDITSLHLDHLRVYWQELLDLHMEMGLNTEEALTYSFQRLDSDISLEIQAPLEDEMTRNLSLQVAFSGATACIAHVDGIHLHVANAGDCRAILGVQEDNGMWSCLPLTRDHNAWNPSELSRLKREHPESEDRTVILDNRLLGVLMPCRAFGDVQLKWSKELQQSVLERGFDTEALNIYQFTPPNYYTPPYLTAKPEVTYHRLRPQDKFLVLASDGLWDVLGNEDVVRLVVEHLAEGGRHKPDLAQRPGNLGLMQSLLLQRKAQGLQAADQNAATRLIRYAIGSNEYGEMEPERLSTMLTLPEDLARMYRDDITVTVVYFNSDSIDASYKGS", "length": 531 }, "evidence": [ { "id": "G3N1T9", "url": "https://omabrowser.org/oma/group/G3N1T9/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "F1NW03-1", "protein_name": "Pyruvate dehydrogenase phosphatase catalytic subunit 2", "gene_name": "PDP2", "tax_id": 9031, "organism": "Gallus gallus", "sequence": { "sequence": "MMSRTVSSWILGSARNSFVLQRRGRLYSICVPNRHKIKWKLVFSKTLLYPAGTCSLDNTFSLRKAFRHTSTEEEEFSFQLSPSQINDILRAGELSHKILDSSCKSANSVLKFESNQLASNTPIEDRRSAATCLQTRGMMFGVFDGHAGSACAQAVSERLLHYIAVSLMSRQTLEEMELAVECMKPVIPILQLHKHPNDVAYREMTSQYFESLRVYWQHLLDLDIEPGFSLEEAMISAFKRLDSDISLEVQAPQENELVRNTALQVAFSGATACVAHIDGVHLHVANAGDCRAILGVHEEDGTWSTLPLTRDHNAYDESEIRRLKREHPRSEEKTLFVNDRLLGILMPSRAFGDVQLKWSKELQHSVLENSCDVGALNIYHYVPPNYHTPPYLTAEPEVTYHKLRGKDKFLIIASDGLWEMLSNEEVVKLVAGHLTELNVQKPQLAFEKPVNLGYLHNLLLQRKNRGITSLDQNIATHLIRHAIGNNEYGEVDQEKLAAMLTLPEDLARMYRDDITITVVYFNSEAIENYYRNNE", "length": 534 }, "evidence": [ { "id": "G3N1T9", "url": "https://omabrowser.org/oma/group/G3N1T9/", "database": "OMA" } ], "glygen_name": "Chicken", "common_name": "Chicken" }, { "uniprot_canonical_ac": "O88484-1", "protein_name": "[Pyruvate dehydrogenase [acetyl-transferring]]-phosphatase 2, mitochondrial", "gene_name": "Pdp2", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MSSTASYRIFNFARNRIAVLRGGRRLYSRAATSRNQVKWRLFSPASLAVNDSSPHGGFALRKAYRHTSTEEEDFHLQLSPEQVSDLLRAGESSHKVLDFNSGVPNSVLRFESNQLAANSPVEDRQGVASCVQTRGTMFGIFDGHGGHACAQAVSERLFYYMAVSLMSHKTLEQMEEAMENMKPLLPILQWLKHPGDSIYKDITSVHLDHLRVYWQELLDLHMETGLSTEEALMYSFQRLDSDISLEIQAPLEDEVTKNLSLQVAFSGATACMAHVDGVHLHIANAGDCRAILGVQGDNGAWSCLPLTCDHNAWNEAELSRLKREHPESEDRTLIIDDRLLGVLLPCRAFGDVQLKWSKELQRNVLERGFDTEALNIYQFTPPHYHTPPYLTAKPEVTYHRLRPQDKFLVLASDGLWDMLDNEDVVRLVVGHLSKVGHQKPALDQRPANLGHMQSLLLQRKASGLHAADQNAATHLIRHAIGSNEYGEMEPERLAAMLTLPEDVARMYRDDITVMVVFFNSESIDTYFKEG", "length": 530 }, "evidence": [ { "id": "G3N1T9", "url": "https://omabrowser.org/oma/group/G3N1T9/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "Q12511-1", "protein_name": "[Pyruvate dehydrogenase [acetyl-transferring]]-phosphatase 1, mitochondrial", "gene_name": "PTC5", "tax_id": 559292, "organism": "Saccharomyces cerevisiae S288C", "sequence": { "sequence": "MSPLTRTVAIKKTVKVLSKCQSGREYTQKFLQRAYSTSHANSTYYSRTKLFISSHSKALNIALLSGSLLLTYSYYSPKKILSLDTINGIKDYSTNTSGNINMPSPNPKGTETQKSQRSQNDQSVLILNDSKIEAKLHDREESHFVNRGTGIFRYDVAQLPSNHPIEDDHVEQIITIPIESEDGKSIEKDLYFFGIFDGHGGPFTSEKLSKDLVRYVAYQLGQVYDQNKTVFHSDPNQLIDSAISKGFLKLDNDLVIESFRKLFQDPNNTNIANTLPAISGSCALLSLYNSTNSILKVAVTGDSRALICGLDNEGNWTVKSLSTDQTGDNLDEVRRIRKEHPGEPNVIRNGRILGSLQPSRAFGDYRYKIKEVDGKPLSDLPEVAKLYFRREPRDFKTPPYVTAEPVITSAKIGENTKFMVMGSDGLFELLTNEEIASLVIRWMDKNMNLAPVKAEPGKLPKVIDVSEDKEAQRPAFRYKDNNSSSPSGSNPEYLIEDKNVATHLIRNALSAGGRKEYVSALVSIPSPMSRRYRDDLTVTVAFFGDSGTPSIVSNATSIVMNPEATTKPKPRL", "length": 572 }, "evidence": [ { "id": "G3N1T9", "url": "https://omabrowser.org/oma/group/G3N1T9/", "database": "OMA" } ], "glygen_name": "Yeast", "common_name": "Baker's yeast" }, { "uniprot_canonical_ac": "Q504M2-1", "protein_name": "[Pyruvate dehydrogenase [acetyl-transferring]]-phosphatase 2, mitochondrial", "gene_name": "Pdp2", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MSSTVSYWIFNSARNRIALLRGGRRLYSRAATSRNLLKWRPFSPALASSALKCGSPPGGFALRKAYRHTSTEEEDFHLQLSPEQVSDLLRAGESSHKVLDFNNGVPNSVLRFESNQLAANSPVEDRQGVATCVQTNGMMFGIFDGHGGHACAQAVSERLFYYMAVSLMSHQTLEQMEEATENMKPLLPILRWLKHPGDSIYKDVTSVHLDHLRVYWQELLDLHMEMGLSIEEALMYSFQRLDSDISLEIQAPLEDEVTRNLSLQVAFSGATACMAHVNGVHLHVANAGDCRAILGVQEENGAWSCLPLTCDHNAWNEAELSRLKREHPESEDRTLIIDDRLLGVLMPCRAFGDVQLKWSKELQRNVLARGFDTEALNIYQFTPPHYYTPPYLTAKPEVTYHRLRRQDKFLVLASDGLWDMLGNEDVVRLVVGHLSKVGRHKPDLDQRPANLGLMQSLLLQRKASGLHAADQNTATHLIRHAIGSNEYGEMEPERLAAMLTLPEDVARMYRDDITVMVVFFNSDSIDTYCKEG", "length": 532 }, "evidence": [ { "id": "G3N1T9", "url": "https://omabrowser.org/oma/group/G3N1T9/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q9P2J9-1", "protein_name": "[Pyruvate dehydrogenase [acetyl-transferring]]-phosphatase 2, mitochondrial", "gene_name": "PDP2", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MSSTVSYWILNSTRNSIATLQGGRRLYSRYVSNRNKLKWRLFSRVPPTLNSSPCGGFTLCKAYRHTSTEEDDFHLQLSPEQINEVLRAGETTHKILDLESRVPNSVLRFESNQLAANSPVEDRRGVASCLQTNGLMFGIFDGHGGHACAQAVSERLFYYVAVSLMSHQTLEHMEGAMESMKPLLPILHWLKHPGDSIYKDVTSVHLDHLRVYWQELLDLHMEMGLSIEEALMYSFQRLDSDISLEIQAPLEDEVTRNLSLQVAFSGATACMAHVDGIHLHVANAGDCRAILGVQEDNGMWSCLPLTRDHNAWNQAELSRLKREHPESEDRTIIMEDRLLGVLIPCRAFGDVQLKWSKELQRSILERGFNTEALNIYQFTPPHYYTPPYLTAEPEVTYHRLRPQDKFLVLASDGLWDMLSNEDVVRLVVGHLAEADWHKTDLAQRPANLGLMQSLLLQRKASGLHEADQNAATRLIRHAIGNNEYGEMEAERLAAMLTLPEDLARMYRDDITVTVVYFNSESIGAYYKGG", "length": 529 }, "evidence": [ { "id": "G3N1T9", "url": "https://omabrowser.org/oma/group/G3N1T9/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" } ], "go_annotation": { "categories": [ { "name": "Molecular Function", "total": 2, "go_terms": [ { "name": "[pyruvate dehydrogenase (acetyl-transferring)]-phosphatase activity", "id": "GO:0004741", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0004741", "evidence": [ { "database": "UniProtKB", "id": "G3N1T9", "url": "https://www.uniprot.org/uniprotkb/G3N1T9" } ], "pmid": "" }, { "name": "metal ion binding", "id": "GO:0046872", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0046872", "evidence": [ { "database": "UniProtKB", "id": "G3N1T9", "url": "https://www.uniprot.org/uniprotkb/G3N1T9" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 1, "go_terms": [ { "name": "mitochondrion", "id": "GO:0005739", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005739", "evidence": [ { "database": "UniProtKB", "id": "G3N1T9", "url": "https://www.uniprot.org/uniprotkb/G3N1T9" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 1, "go_terms": [ { "name": "T-helper cell differentiation", "id": "GO:0042093", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0042093", "evidence": [ { "database": "UniProtKB", "id": "G3N1T9", "url": "https://www.uniprot.org/uniprotkb/G3N1T9" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 259, "end_pos": 261, "annotation": "n_glycosylation_sequon" }, { "start_pos": 33, "end_pos": 35, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [ { "id": "12669", "name": "", "equation": "O-phospho-L-seryl-[pyruvate dehydrogenase E1 alpha subunit] + H2O = L-seryl-[pyruvate dehydrogenase E1 alpha subunit] + phosphate", "summary": "", "cellular_location": "", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [ "P35816-1", "G3N1T9-1" ], "evidence": [ { "id": "12669", "database": "Rhea", "url": "https://www.rhea-db.org/rhea/12669" } ] }, { "id": "R-BTA-204169", "name": "PDP1,2 dephosphorylate p-lipo-PDH", "equation": "", "summary": "This event has been computationally inferred from an event that has been demonstrated in another species.

The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.

More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "cellular_location": "mitochondrial matrix", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [ "P35816-1", "A7MB35-1", "G3N1T9-1", "P11966-1", "F1N206-1" ], "evidence": [ { "id": "R-BTA-204169", "database": "Reactome", "url": "https://www.reactome.org/PathwayBrowser/#R-BTA-204169" } ] } ], "reaction_participants": [], "reaction_enzymes": [ { "uniprot_ac": "A7MB35", "gene_name": "PDHA1", "activity": [ { "ec_number": "1.2.4.1", "activity": "N(6)-[(R)-lipoyl]-L-lysyl-[protein] + pyruvate + H(+) = N(6)-[(R)-S(8)-acetyldihydrolipoyl]-L-lysyl-[protein] + CO2.", "evidence": [ { "id": "A7MB35", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A7MB35" } ] }, { "ec_number": "1.2.4.1", "activity": "", "evidence": [ { "id": "A7MB35", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A7MB35" } ] } ] }, { "uniprot_ac": "F1N206", "gene_name": "DLD", "activity": [ { "ec_number": "1.8.1.4", "activity": "N(6)-[(R)-dihydrolipoyl]-L-lysyl-[protein] + NAD(+) = N(6)-[(R)-lipoyl]-L-lysyl-[protein] + NADH + H(+).", "evidence": [ { "id": "F1N206", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1N206" } ] }, { "ec_number": "1.8.1.4", "activity": "", "evidence": [ { "id": "F1N206", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1N206" } ] } ] }, { "uniprot_ac": "G3N1T9", "gene_name": "PDP2", "activity": [ { "ec_number": "3.1.3.43", "activity": "O-phospho-L-seryl-[pyruvate dehydrogenase E1 alpha subunit] + H2O = L-seryl-[pyruvate dehydrogenase E1 alpha subunit] + phosphate.", "evidence": [ { "id": "G3N1T9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3N1T9" } ] }, { "ec_number": "3.1.3.43", "activity": "", "evidence": [ { "id": "G3N1T9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3N1T9" } ] } ] }, { "uniprot_ac": "P11966", "gene_name": "PDHB", "activity": [ { "ec_number": "1.2.4.1", "activity": "N(6)-[(R)-lipoyl]-L-lysyl-[protein] + pyruvate + H(+) = N(6)-[(R)-S(8)-acetyldihydrolipoyl]-L-lysyl-[protein] + CO2.", "evidence": [ { "id": "P11966", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P11966" } ] }, { "ec_number": "1.2.4.1", "activity": "", "evidence": [ { "id": "P11966", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P11966" } ] } ] }, { "uniprot_ac": "P35816", "gene_name": "PDP1", "activity": [ { "ec_number": "3.1.3.43", "activity": "O-phospho-L-seryl-[pyruvate dehydrogenase E1 alpha subunit] + H2O = L-seryl-[pyruvate dehydrogenase E1 alpha subunit] + phosphate.", "evidence": [ { "id": "P35816", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P35816" } ] }, { "ec_number": "3.1.3.43", "activity": "", "evidence": [ { "id": "P35816", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P35816" } ] } ] } ], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "G3N1T9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3N1T9" }, { "id": "PS51746", "database": "PROSITE", "url": "https://prosite.expasy.org/PS51746" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "PPM-type phosphatase", "eco_id": "ECO_0000259", "start_pos": 108, "end_pos": 519, "start_aa": "Val", "end_aa": "Phe", "glycosite_overlap": [] } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [ { "ec_number": "3.1.3.43", "ec_name": "O-phospho-L-seryl-[pyruvate dehydrogenase E1 alpha subunit] + H2O = L-seryl-[pyruvate dehydrogenase E1 alpha subunit] + phosphate.", "evidence": [ { "id": "3.1.3.43", "database": "Rhea", "url": "https://www.rhea-db.org/rhea/?query=ec:3.1.3.43" }, { "id": "3.1.3.43", "database": "BRENDA Enzymes", "url": "https://www.brenda-enzymes.org/enzyme.php?ecno=3.1.3.43" } ] } ], "cluster_types": [ { "name": "homologset.oma", "label": "OMA Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 259, "end_pos": 261 }, { "start_pos": 33, "end_pos": 35 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ], "tool_support": { "graph_view": "yes" } }, { "uniprot_canonical_ac": "G3N1Y0-1", "uniprot_ac": "G3N1Y0", "uniprot_id": "G3N1Y0_BOVIN", "mass": { "chemical_mass": 70031.0, "monoisotopic_mass": 70031.0 }, "refseq": {}, "gene_names": [ { "name": "KLHL31", "type": "recommended", "evidence": [ { "id": "G3N1Y0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3N1Y0" } ] } ], "protein_names": [ { "name": "Kelch-like protein 31", "type": "recommended", "evidence": [ { "id": "G3N1Y0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3N1Y0/entry#names_and_taxonomy" } ] }, { "name": "Kelch repeat and BTB domain-containing protein 1", "type": "synonym", "evidence": [ { "id": "G3N1Y0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3N1Y0/entry#names_and_taxonomy" } ] }, { "name": "Kelch-like protein KLHL", "type": "synonym", "evidence": [ { "id": "G3N1Y0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3N1Y0/entry#names_and_taxonomy" } ] } ], "function": [ { "annotation": "Transcriptional repressor in MAPK/JNK signaling pathway to regulate cellular functions. Overexpression inhibits the transcriptional activities of both the TPA-response element (TRE) and serum response element (SRE).", "evidence": [ { "database": "UniProtKB", "id": "G3N1Y0", "url": "https://www.uniprot.org/uniprotkb/G3N1Y0#function" }, { "database": "UniProtKB", "id": "ARBA00054209", "url": "https://www.uniprot.org/uniprotkb/ARBA00054209#function" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Bos taurus", "taxid": 9913, "evidence": [ { "database": "UniProtKB", "id": "G3N1Y0", "url": "https://www.uniprot.org/uniprotkb/G3N1Y0" } ], "common_name": "Bovine", "glygen_name": "Bovine", "reference_species": "Bos taurus [9913]" } ], "gene": [ { "name": "KLHL31", "url": "https://www.uniprot.org/uniprotkb/G3N1Y0", "locus": { "chromosome": "23", "start_pos": 6847565, "end_pos": 6831313, "strand": "-", "evidence": [ { "database": "Ensembl Gene", "id": "ENSBTAG00000018167", "url": "https://www.ensembl.org/id/ENSBTAG00000018167" } ] } } ], "crossref": [ { "id": "G3N1Y0", "url": "https://alphafold.ebi.ac.uk/entry/G3N1Y0", "database": "AlphaFoldDB", "categories": [] }, { "id": "ENSBTAG00000018167", "url": "https://bgee.org/?page=gene&gene_id=ENSBTAG00000018167", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "cd18260", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd18260", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "cd18470", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd18470", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "IPR000210", "url": "https://www.ebi.ac.uk/interpro/entry/IPR000210", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR006652", "url": "https://www.ebi.ac.uk/interpro/entry/IPR006652", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR011333", "url": "https://www.ebi.ac.uk/interpro/entry/IPR011333", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR011705", "url": "https://www.ebi.ac.uk/interpro/entry/IPR011705", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR015915", "url": "https://www.ebi.ac.uk/interpro/entry/IPR015915", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR017096", "url": "https://www.ebi.ac.uk/interpro/entry/IPR017096", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR030604", "url": "https://www.ebi.ac.uk/interpro/entry/IPR030604", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "FNSWIHL", "url": "https://omabrowser.org/oma/group/FNSWIHL/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "G3N1Y0", "url": "https://www.orthodb.org/?gene=G3N1Y0", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR45632", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR45632", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR45632:SF17", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR45632:SF17", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00651", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00651", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF01344", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF01344", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF07707", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF07707", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF24681", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF24681", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "G3N1Y0", "url": "https://www.uniprot.org/uniprotkb/G3N1Y0", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "G3N1Y0-1", "url": "https://www.uniprot.org/uniprotkb/G3N1Y0-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MAPKKKTVRKNKADVNEMTIIVEDSPLNKLNALNGLLEGGNGLSCISSELTDASYGPNLLEGLSKMRQEGFLCDLVISTKTKSFDVHKSVMASCSEYFYNILKKDPSTQRVDLNDIAPLGLATVIAYAYTGKLTLSLYTIGSIISAAVYLQIHTLVKMCSDFLIQEMSVENCMYIANIAETYSLRNAKAAAQKFIRDNFLEFAETDHFMKLTFEQINELLIDDDLQLPSEIVAFQIAMKWLEFDQKRVKYAADLLSNIRFGTISAQDLVNYVQSVPRMMQDADCHKLLVDAMNYHLLPYHQNTLQSRRTRIRGGCRVLVTVGGRPGLTEKSLSRDVLYRDPEIGWSKLTEMPAKSFNQCVAVMDGFLYVAGGEDQNDARNQAKHAVSNFCRYDPRFNTWIHLANMTQRRTHFSLSVFNGLLYAVGGRNAEGSLASLECYVPSANQWLPKAPLEVARCCHASAVAEGRVLVTGGYIGGAYSRSVCAYDPARDAWQERPALGTPRGWHCAVALGERVFVMGGSQLGPRGERVDVLTVESFCPASGQWSYAAPLPVGVSTAGASVLHGRAYLLGGWNEGERKYKKCIQCFNPELNEWTEDDELPEATVGVSCCALAMPNPVTRESRASSVSSVPVSI", "length": 634, "header": "tr|G3N1Y0-1|G3N1Y0_BOVIN Isoform 1 of Kelch-like protein 31 OS=Bos taurus OX=9913 GN=KLHL31 PE=4 SV=1 CANONICAL=G3N1Y0-1" }, "isoforms": [ { "isoform_ac": "G3N1Y0-1", "url": "https://www.uniprot.org/uniprotkb/G3N1Y0/entry", "sequence": { "sequence": "MAPKKKTVRKNKADVNEMTIIVEDSPLNKLNALNGLLEGGNGLSCISSELTDASYGPNLLEGLSKMRQEGFLCDLVISTKTKSFDVHKSVMASCSEYFYNILKKDPSTQRVDLNDIAPLGLATVIAYAYTGKLTLSLYTIGSIISAAVYLQIHTLVKMCSDFLIQEMSVENCMYIANIAETYSLRNAKAAAQKFIRDNFLEFAETDHFMKLTFEQINELLIDDDLQLPSEIVAFQIAMKWLEFDQKRVKYAADLLSNIRFGTISAQDLVNYVQSVPRMMQDADCHKLLVDAMNYHLLPYHQNTLQSRRTRIRGGCRVLVTVGGRPGLTEKSLSRDVLYRDPEIGWSKLTEMPAKSFNQCVAVMDGFLYVAGGEDQNDARNQAKHAVSNFCRYDPRFNTWIHLANMTQRRTHFSLSVFNGLLYAVGGRNAEGSLASLECYVPSANQWLPKAPLEVARCCHASAVAEGRVLVTGGYIGGAYSRSVCAYDPARDAWQERPALGTPRGWHCAVALGERVFVMGGSQLGPRGERVDVLTVESFCPASGQWSYAAPLPVGVSTAGASVLHGRAYLLGGWNEGERKYKKCIQCFNPELNEWTEDDELPEATVGVSCCALAMPNPVTRESRASSVSSVPVSI", "length": 634, "header": "tr|G3N1Y0-1|G3N1Y0_BOVIN Isoform 1 of Kelch-like protein 31 OS=Bos taurus OX=9913 GN=KLHL31 PE=4 SV=1 CANONICAL=G3N1Y0-1" }, "locus": { "chromosome": "23", "start_pos": 6847200, "end_pos": 6843587, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000065223.4", "url": "https://www.ensembl.org/id/ENSBTAT00000065223.4" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000055884.1", "url": "https://www.ensembl.org/id/ENSBTAP00000055884.1" } ] } } ], "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "other", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 320, "start_aa": "Thr", "end_pos": 320, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr320", "evidence": [ { "id": "", "database": "GlyGen", "url": "https://data.glygen.org/" } ], "filter_code": "000000000000000010000.00000000001000.0.01000" } ], "phosphorylation": [], "glycation": [], "keywords": [ "glycoprotein", "glycoprotein_predicted" ], "publication": [], "pathway": [], "orthologs": [ { "uniprot_canonical_ac": "A0A8V0X821-1", "protein_name": "Kelch like family member 31", "gene_name": "KLHL31", "tax_id": 9031, "organism": "Gallus gallus", "sequence": { "sequence": "MAPKKKNVKKNKAADISEMTIIVEDGPLSKLNGLNGLLDGGNGFSCVSSEVSDPSYSPNLLEGLSRMRLENFLCDLTISTKTKSFNVHKVVMASISDYFHNILKKDPSTQRVDLNDVSPLGLATVITYAYTGKLTLSLYTIGSIISTAIYLQIHTLVKMCCDFLTQEISVENCMYIANIAETYGLKTTKEAAHKFIRDNFIEFSETDQFLKLTFDQINELLADDDLQLPSEIVAFQIAIKWLEFDQKRVKFAADLLGNIRFGTISAQDLVNYVQTVPRMMQDADCHKLLVDAMNYHLLPYHQNTLQSRRTRIRGGFRVLVTVGGRPALTEKSLSRDILYRDPENGWKKLSEMPAKSFNQCVTVMDGFLYVAGGEDQNDARNQAKHAVSNFCRYDPRFNTWIHLANMNQKRTHFSLNVFNGLLFAVGGRNLEGCLSSMECYVPATNQWQMKAPLEVPRCCHASAVVDGRILVTGGYINNAYSRSVCMYDPSNDSWQDKSSLSTPRGWHCAVSLLERVYVMGGSQLGGRGERVDVLPVECYSPYTGQWSYVAPLQTGVSTAGASMLDGKIYLVGGWNEIEKKYKKCIQCYNPDLNEWTEEDELPEATVGVSCCTISMPNTKTRESRASSVSSVPVSI", "length": 635 }, "evidence": [ { "id": "G3N1Y0", "url": "https://omabrowser.org/oma/group/G3N1Y0/", "database": "OMA" } ], "glygen_name": "Chicken", "common_name": "Chicken" }, { "uniprot_canonical_ac": "D3ZLT6-1", "protein_name": "Kelch-like protein 31", "gene_name": "Klhl31", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MAPKKKTLKKNKPEINEMTIIVEDSPLNKLNALNGLLGGENSLSCVSSELTDTSYGPNLLEGLSKMRQESFLCDLVIGTKTKSFDVHKSVMASCSEYFYNILKNDPSTKRVDLNDIAPLGLATVIAYAYTGKLTLSLYTIGSIISAAVYLQIHTLVKMCSDFLIREISVENCMYVVNMAETYCLKNAKATAQKFIRDNFIEFADSEQFMKLTFEQINELLIDDDLQLPSELVAFQIAMKWIEFDQKRVKHAADLLSNIRFGTISAQDLVNYVQTVPRMMQDADCHKLLVDAMNYHLLPYHQNTLQSRRTRIRGGCRVLITVGGRPGLTEKSLSRDVLYRDPENGWSKLTEMPAKSFNQCVAVMDGFLYVAGGEDQNDARNQAKHAVSNFCRYDPRFNTWIHLGSMNQKRTHFSLSVFNGLLYAVGGRNAEGSLASLECYVPSTNQWQPKAPLEVARCCHASAVADGRVIVTGGYIGSAYSRSVCAYDPALDAWQELPGLSTPRGWHCSVALGDRVYVMGGSQLGPRGERVDVLTVESFSPVARQWSFVAPLPVGVSTAGVSALHGRAYLVGGWNEGEKKYKKCIQCFNPELNEWMEDDELPEATVGVSCCTLAMPNSVSRESRASSVSSVPVSI", "length": 634 }, "evidence": [ { "id": "G3N1Y0", "url": "https://omabrowser.org/oma/group/G3N1Y0/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "F1RZV8-1", "protein_name": "Kelch-like protein 31", "gene_name": "KLHL31", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MAPKKKTVKKNKGDVNEMTIIVEDSPLHKLNALNGLLEGGNGLSCISSELTDASYGPNLLEGLSKMRQENFLCDLVIGTKTKSFDVHKSVMASCSEYFYNILKKDPSTQRVDLNDISPLGLATVIAYAYTGKLTLSLYTIGSILSAAVYLQIHTLVKMCSDFLIQEMSVENCMYIANIAETYSLRNAKAAAQKFIRDNFLEFAESDQFMKLTFEQINELLIDDDLQLPSEIVAFQIAMKWLESDQKRVKYAADLLSNIRFGTISAQDLVNYVQSVPRMMQDADCHKLLVDAMNYHLLPYHQNTLQSRRTRIRGGCRVLVTVGGRPGLTEKSLSRDVLYRDPEYGWSKLTEMPAKSFNQCVAVMDGFLYVAGGEDQNDARNQAKHAVSNFCRYDPRFNTWIHLASMNQKRTHFSLSVFNGLLYAVGGRNAEGSLASLECYVPSANQWQPKAPLEVARCCHASAVADGRVLVTGGYIGGAYSRSVCAYDPARDAWQELPALSTPRGWHCAVALGERVYVMGGSQVGPRGERVDVLTVEGFSPATGQWSYAAPLPVGVSTAGASALHGRAYLVGGWNEGERKYKKCIQCFNPELNEWTEDDELPEATVGVSCCTLAMPNHVTRESRASSVSSVPVSI", "length": 634 }, "evidence": [ { "id": "G3N1Y0", "url": "https://omabrowser.org/oma/group/G3N1Y0/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "Q6Q7X9-1", "protein_name": "Kelch-like protein 31", "gene_name": "klhl31", "tax_id": 7955, "organism": "Danio rerio", "sequence": { "sequence": "MAPKKNKAAKKSKADINEMTIMVEDSPSNKINGLNTLLEGGNGFSCISTEVTDPVYAPNLLEGLGHMRQDSFLCDLTVATKSKSFDVHKVVMASCSEYIQNMLRKDPSLKKIELSDLSPVGLATVITYAYSGKLTLSLYTIGSTISAALLLQIHTLVKMCSDFLMRETSVENCMYVVNIADTYNLKETKEAAQKFMRENFIEFSEMEQFLKLTYEQINEFLTDDSLQLPSELTAFQIAVKWLDFDEKRLKYAPDLLSNIRFGTITPQDLVSHVQNVPRMMQDAECHRLLVDAMNYHLLPFQQNILQSRRTKVRGGLRVLLTVGGRPALTEKSLSKDILYRDEDNVWNKLTEMPAKSFNQCVAVLDGFLYVAGGEDQNDARNQAKHAVSNFSRYDPRFNTWIHLANMIQKRTHFSLNTFNGLLFAVGGRNSDGCQASVECYVPSSNQWQMKAPMEVPRCCHASSVIDGKILVSGGYINNAYSRAVCSYDPSTDSWQDKNSLSSPRGWHCSVTVGDRAYVLGGSQLGGRGERVDVLPVECYNPHSGQWSYVAPLLTGVSTAGAATLNNKIYLLGGWNEIEKKYKKCIQVYNPDLNEWTEDDELPEATVGISCCVVTIPTRKTRESRASSVSSAPVSI", "length": 635 }, "evidence": [ { "id": "G3N1Y0", "url": "https://omabrowser.org/oma/group/G3N1Y0/", "database": "OMA" } ], "glygen_name": "Zebrafish", "common_name": "Zebrafish" }, { "uniprot_canonical_ac": "Q8BWA5-1", "protein_name": "Kelch-like protein 31", "gene_name": "Klhl31", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MAPKKKTIKKNKAEINEMTIIVEDSPLSKLNALNGLLEGSNSLSCVSSELTDTSYGPNLLEGLSKMRQESFLCDLVIGTKTKSFDVHKSVMASCSEYFYNILKNDPSTKRVDLNDIAPLGLATVIAYAYTGKLTLSLYTIGSIISAAVYLQIHTLVKMCSDFLIREISVENCMYVVNIAETYSLKNAKATAQKFIRDNFIEFAESEQFMKLTFEQINELLVDDDLQLPSELVAFQIAMKWLEFDQKRVKHAADLLSNIRFGTISAQDLVNYVQTVPRMMQDADCHKLLVDAMNYHLLPYHQNTLQSRRTRIRGGCRVLITVGGRPGLTEKSLSRDILYRDPENGWSKLTEMPAKSFNQCVAVMDGFLYVAGGEDQNDARNQAKHAVSNFCRYDPRFNTWIHLGSMNQKRTHFSLSVFNGLLYAVGGRNSEGSLASLECYVPSTNQWQPKAPLEVARCCHASAVADGRVIVTGGYIGSAYSRSVCAYDPALDAWQELPQLSTPRGWHCAVALGDRLYVMGGSQLGPRGERVDVLTVESFSPAARQWSFVAPLPVGVSTAGVSALHGRAYLLGGWNEGDKKYKKCIQCFNPELNEWTEDDELPEATVGVSCCTLAMPNSVSRESRASSVSSVPVSI", "length": 634 }, "evidence": [ { "id": "G3N1Y0", "url": "https://omabrowser.org/oma/group/G3N1Y0/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q9H511-1", "protein_name": "Kelch-like protein 31", "gene_name": "KLHL31", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MAPKKKIVKKNKGDINEMTIIVEDSPLNKLNALNGLLEGGNGLSCISSELTDASYGPNLLEGLSKMRQENFLCDLVIGTKTKSFDVHKSVMASCSEYFYNILKKDPSIQRVDLNDISPLGLATVIAYAYTGKLTLSLYTIGSIISAAVYLQIHTLVKMCSDFLIREMSVENCMYVVNIAETYSLKNAKAAAQKFIRDNFLEFAESDQFMKLTFEQINELLIDDDLQLPSEIVAFQIAMKWLEFDQKRVKYAADLLSNIRFGTISAQDLVNYVQSVPRMMQDADCHRLLVDAMNYHLLPYHQNTLQSRRTRIRGGCRVLVTVGGRPGLTEKSLSRDILYRDPENGWSKLTEMPAKSFNQCVAVMDGFLYVAGGEDQNDARNQAKHAVSNFCRYDPRFNTWIHLASMNQKRTHFSLSVFNGLVYAAGGRNAEGSLASLECYVPSTNQWQPKTPLEVARCCHASAVADGRVLVTGGYIANAYSRSVCAYDPASDSWQELPNLSTPRGWHCAVTLSDRVYVMGGSQLGPRGERVDVLTVECYSPATGQWSYAAPLQVGVSTAGVSALHGRAYLVGGWNEGEKKYKKCIQCFSPELNEWTEDDELPEATVGVSCCTLSMPNNVTRESRASSVSSVPVSI", "length": 634 }, "evidence": [ { "id": "G3N1Y0", "url": "https://omabrowser.org/oma/group/G3N1Y0/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" } ], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 2, "go_terms": [ { "name": "nucleus", "id": "GO:0005634", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005634", "evidence": [ { "database": "UniProtKB", "id": "G3N1Y0", "url": "https://www.uniprot.org/uniprotkb/G3N1Y0" } ], "pmid": "" }, { "name": "cytoplasm", "id": "GO:0005737", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005737", "evidence": [ { "database": "UniProtKB", "id": "G3N1Y0", "url": "https://www.uniprot.org/uniprotkb/G3N1Y0" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 2, "go_terms": [ { "name": "DNA-templated transcription", "id": "GO:0006351", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006351", "evidence": [ { "database": "UniProtKB", "id": "G3N1Y0", "url": "https://www.uniprot.org/uniprotkb/G3N1Y0" } ], "pmid": "" }, { "name": "negative regulation of JNK cascade", "id": "GO:0046329", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0046329", "evidence": [ { "database": "UniProtKB", "id": "G3N1Y0", "url": "https://www.uniprot.org/uniprotkb/G3N1Y0" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 404, "end_pos": 406, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [ { "pdb_id": "AF-G3N1Y0-F1", "pdb_chain": "global", "start_pos": 1, "end_pos": 634, "overlap": "1.0", "method": "AlphaFold", "type": "alphafold", "resolution": -1.0, "url": "https://data.glygen.org/ln2downloads/pdb/current/AF-G3N1Y0-F1.pdb", "url_external": "https://alphafold.ebi.ac.uk/entry/G3N1Y0" } ], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "G3N1Y0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3N1Y0" }, { "id": "PS50097", "database": "PROSITE", "url": "https://prosite.expasy.org/PS50097" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "BTB", "eco_id": "ECO_0000259", "start_pos": 73, "end_pos": 137, "start_aa": "Cys", "end_aa": "Leu", "glycosite_overlap": [] } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "homologset.oma", "label": "OMA Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [ 320 ], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 404, "end_pos": 406 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 1 }, { "field": "total_sites", "count": 1 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 1 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "exact_sites", "count": 1 }, { "field": "exact_o_linked_sites", "count": 1 }, { "field": "fuzzy_sites", "count": 0 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_pos", "start_aa", "end_pos", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 1 }, { "field": "total_sites", "count": 1 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 1 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "exact_sites", "count": 1 }, { "field": "exact_o_linked_sites", "count": 1 }, { "field": "fuzzy_sites", "count": 0 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_pos", "start_aa", "end_pos", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ], "tool_support": { "graph_view": "yes" } }, { "uniprot_canonical_ac": "G3N1Y4-1", "uniprot_ac": "G3N1Y4", "uniprot_id": "G3N1Y4_BOVIN", "mass": { "chemical_mass": 57692.0, "monoisotopic_mass": 57692.0 }, "refseq": {}, "gene_names": [ { "name": "HHLA1", "type": "recommended", "evidence": [ { "id": "G3N1Y4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3N1Y4" } ] } ], "protein_names": [ { "name": "HHLA1 neighbor of OC90", "type": "synonym", "evidence": [ { "id": "G3N1Y4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3N1Y4/entry#names_and_taxonomy" } ] } ], "function": [], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Bos taurus", "taxid": 9913, "evidence": [ { "database": "UniProtKB", "id": "G3N1Y4", "url": "https://www.uniprot.org/uniprotkb/G3N1Y4" } ], "common_name": "Bovine", "glygen_name": "Bovine", "reference_species": "Bos taurus [9913]" } ], "gene": [ { "name": "HHLA1", "url": "https://www.uniprot.org/uniprotkb/G3N1Y4", "locus": { "chromosome": "14", "start_pos": 9076584, "end_pos": 9051285, "strand": "-", "evidence": [ { "database": "Ensembl Gene", "id": "ENSBTAG00000034196", "url": "https://www.ensembl.org/id/ENSBTAG00000034196" } ] } } ], "crossref": [ { "id": "G3N1Y4", "url": "https://alphafold.ebi.ac.uk/entry/G3N1Y4", "database": "AlphaFoldDB", "categories": [] }, { "id": "ENSBTAG00000034196", "url": "https://bgee.org/?page=gene&gene_id=ENSBTAG00000034196", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "IPR037643", "url": "https://www.ebi.ac.uk/interpro/entry/IPR037643", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "PTHR15299", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR15299", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR15299:SF3", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR15299:SF3", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "G3N1Y4", "url": "https://www.uniprot.org/uniprotkb/G3N1Y4", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "G3N1Y4-1", "url": "https://www.uniprot.org/uniprotkb/G3N1Y4-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MPGFLLRGPLVRLCLDLTCVLSLFNTVSSFRGEAEKENVMTFLPTTVSSLREEERREKGIVFLDTTELPARSVDLSALNLTELVNGMLNRALKDSKNFFSLLSVTSYSSFAFHKFSVAIYNISNLKTVDPANFPTRYCYCLNNQTNDLSDFTALLVDIIGNSSSHLTEMFKSASILSVSQTNESDCIFICMMTGKSGRNLSDFWELVEKSPVINYTFTSNISGVLGAATTASALTSQLTPTSQQTLPRTSPPRGAQRAGVSALRTSSGTDTTPPSEAEQTLKTNVLPECPARATATLDMPSPTLPASTTRKVARTPRVTAHRQAQASTLPTPWAQVTSEKTPGGPPWETLASLPTSPKAEETMNTRSLSQPPAGTAAAVGSPIQTSPTSGPSTPGTQTPSPTKAPAPKYPQAGDLPAVWTFIPGEESALIPGTHQFSRCPEPLPKEGAMTAAPLALTVQKLNPCLMELCRFFQQCLCTSQKSEPRMEAGRYCLDYYSWFLKNATYICQRVKRVFHSHTLKQKCLENICKSV", "length": 531, "header": "tr|G3N1Y4-1|G3N1Y4_BOVIN Isoform 1 of HHLA1 neighbor of OC90 OS=Bos taurus OX=9913 GN=HHLA1 PE=4 SV=3 CANONICAL=G3N1Y4-1" }, "isoforms": [ { "isoform_ac": "G3N1Y4-1", "url": "https://www.uniprot.org/uniprotkb/G3N1Y4/entry", "sequence": { "sequence": "MPGFLLRGPLVRLCLDLTCVLSLFNTVSSFRGEAEKENVMTFLPTTVSSLREEERREKGIVFLDTTELPARSVDLSALNLTELVNGMLNRALKDSKNFFSLLSVTSYSSFAFHKFSVAIYNISNLKTVDPANFPTRYCYCLNNQTNDLSDFTALLVDIIGNSSSHLTEMFKSASILSVSQTNESDCIFICMMTGKSGRNLSDFWELVEKSPVINYTFTSNISGVLGAATTASALTSQLTPTSQQTLPRTSPPRGAQRAGVSALRTSSGTDTTPPSEAEQTLKTNVLPECPARATATLDMPSPTLPASTTRKVARTPRVTAHRQAQASTLPTPWAQVTSEKTPGGPPWETLASLPTSPKAEETMNTRSLSQPPAGTAAAVGSPIQTSPTSGPSTPGTQTPSPTKAPAPKYPQAGDLPAVWTFIPGEESALIPGTHQFSRCPEPLPKEGAMTAAPLALTVQKLNPCLMELCRFFQQCLCTSQKSEPRMEAGRYCLDYYSWFLKNATYICQRVKRVFHSHTLKQKCLENICKSV", "length": 531, "header": "tr|G3N1Y4-1|G3N1Y4_BOVIN Isoform 1 of HHLA1 neighbor of OC90 OS=Bos taurus OX=9913 GN=HHLA1 PE=4 SV=3 CANONICAL=G3N1Y4-1" }, "locus": { "chromosome": "14", "start_pos": 9075580, "end_pos": 9051285, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000064134.3", "url": "https://www.ensembl.org/id/ENSBTAT00000064134.3" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000055888.3", "url": "https://www.ensembl.org/id/ENSBTAP00000055888.3" } ] } } ], "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "other", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 393, "start_aa": "Thr", "end_pos": 393, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr393", "evidence": [ { "id": "", "database": "GlyGen", "url": "https://data.glygen.org/" } ], "filter_code": "000000000000000010000.00000000001000.0.01000" } ], "phosphorylation": [], "glycation": [], "keywords": [ "glycoprotein", "glycoprotein_predicted" ], "publication": 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"start_pos": 1, "end_pos": 531, "overlap": "1.0", "method": "AlphaFold", "type": "alphafold", "resolution": -1.0, "url": "https://data.glygen.org/ln2downloads/pdb/current/AF-G3N1Y4-F1.pdb", "url_external": "https://alphafold.ebi.ac.uk/entry/G3N1Y4" } ], "lectin_list": [], "domain_list": [], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [ 393 ], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 121, "end_pos": 123 }, { "start_pos": 143, "end_pos": 145 }, { "start_pos": 161, "end_pos": 163 }, { "start_pos": 182, "end_pos": 184 }, { "start_pos": 199, "end_pos": 201 }, { "start_pos": 214, "end_pos": 216 }, { "start_pos": 220, "end_pos": 222 }, { "start_pos": 502, "end_pos": 504 }, { "start_pos": 79, "end_pos": 81 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": 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{ "field": "exact_sites", "count": 1 }, { "field": "exact_o_linked_sites", "count": 1 }, { "field": "fuzzy_sites", "count": 0 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_pos", "start_aa", "end_pos", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", 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} ] }, { "name": "GPR85", "type": "synonym", "evidence": [ { "id": "NP_001068618", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001068618" } ] } ], "protein_names": [ { "name": "G protein-coupled receptor 85", "type": "synonym", "evidence": [ { "id": "G3N1Y5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3N1Y5/entry#names_and_taxonomy" } ] }, { "name": "probable G-protein coupled receptor 85", "type": "synonym", "evidence": [ { "id": "NP_001068618", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001068618" } ] } ], "function": [ { "annotation": "Orphan receptor.", "evidence": [ { "database": "UniProtKB", "id": "G3N1Y5", "url": "https://www.uniprot.org/uniprotkb/G3N1Y5#function" }, { "database": "UniProtKB", "id": "ARBA00035627", "url": "https://www.uniprot.org/uniprotkb/ARBA00035627#function" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Bos taurus", "taxid": 9913, "evidence": [ { "database": "UniProtKB", "id": "G3N1Y5", "url": "https://www.uniprot.org/uniprotkb/G3N1Y5" } ], "common_name": "Bovine", "glygen_name": "Bovine", "reference_species": "Bos taurus [9913]" } ], "gene": [ { "name": "GPR85", "url": "https://www.uniprot.org/uniprotkb/G3N1Y5", "locus": { "chromosome": "4", "start_pos": 55326426, "end_pos": 55322299, "strand": "-", "evidence": [ { "database": "Ensembl Gene", "id": "ENSBTAG00000032844", "url": "https://www.ensembl.org/id/ENSBTAG00000032844" } ] } } ], "crossref": [ { "id": "ENSBTAG00000032844", "url": "https://bgee.org/?page=gene&gene_id=ENSBTAG00000032844", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "cd15218", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd15218", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "504208", "url": "https://www.ncbi.nlm.nih.gov/gene/504208", "database": "GeneID", "categories": [ "Genome 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"PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR19268:SF7", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR19268:SF7", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00001", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00001", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "NP_001068618", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001068618", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "G3N1Y5", "url": "https://www.uniprot.org/uniprotkb/G3N1Y5", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "G3N1Y5-1", "url": "https://www.uniprot.org/uniprotkb/G3N1Y5-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MANYSHAADNILQNLSPLTAFLKLTSLGFIIGVSVVGNLLISILLVKDKTLHRAPYYFLLDLCCSDILRSAICFPFVFNSVKNGSTWTYGTLTCKVIAFLGVLSCFHTAFMLFCISVTRYLAIAHHRFYTKRLTFWTCLAVICMVWTLSVAMAFPPVLDVGTYSFIREEDQCTFQHRSFRANDSLGFMLLLALILLATQLVYLKLIFFVHDRRKMKPVQFVAAVSQNWTFHGPGASGQAAANWLAGFGRGPTPPTLLGIRQNANTTSRRRLLVLDEFKMEKRISRMFYIMTFLFLTLWGPYLVACYWRVFARGPVVPGGFLTAAVWMSFAQAGINPFVCIFSNRELRRCFSTTLLYCRKSRLPREPYCVI", "length": 370, "header": "tr|G3N1Y5-1|G3N1Y5_BOVIN Isoform 1 of G protein-coupled receptor 85 OS=Bos taurus OX=9913 GN=GPR85 PE=4 SV=1 CANONICAL=G3N1Y5-1" }, "isoforms": [ { "isoform_ac": "G3N1Y5-1", "url": "https://www.uniprot.org/uniprotkb/G3N1Y5/entry", "sequence": { "sequence": "MANYSHAADNILQNLSPLTAFLKLTSLGFIIGVSVVGNLLISILLVKDKTLHRAPYYFLLDLCCSDILRSAICFPFVFNSVKNGSTWTYGTLTCKVIAFLGVLSCFHTAFMLFCISVTRYLAIAHHRFYTKRLTFWTCLAVICMVWTLSVAMAFPPVLDVGTYSFIREEDQCTFQHRSFRANDSLGFMLLLALILLATQLVYLKLIFFVHDRRKMKPVQFVAAVSQNWTFHGPGASGQAAANWLAGFGRGPTPPTLLGIRQNANTTSRRRLLVLDEFKMEKRISRMFYIMTFLFLTLWGPYLVACYWRVFARGPVVPGGFLTAAVWMSFAQAGINPFVCIFSNRELRRCFSTTLLYCRKSRLPREPYCVI", "length": 370, "header": "tr|G3N1Y5-1|G3N1Y5_BOVIN Isoform 1 of G protein-coupled receptor 85 OS=Bos taurus OX=9913 GN=GPR85 PE=4 SV=1 CANONICAL=G3N1Y5-1" }, "locus": { "chromosome": "4", "start_pos": 55325092, "end_pos": 55323983, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000151590.1", "url": "https://www.ensembl.org/id/ENSBTAT00000151590.1" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000104095.1", "url": "https://www.ensembl.org/id/ENSBTAP00000104095.1" } ] } } ], "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "other", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 252, "start_aa": "Thr", "end_pos": 252, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr252", "evidence": [ { "id": "", "database": "GlyGen", "url": "https://data.glygen.org/" } ], "filter_code": "000000000000000010000.00000000001000.0.01000" } ], "phosphorylation": [], "glycation": [], "keywords": [ "glycoprotein", "glycoprotein_predicted" ], "publication": [], "pathway": [ { "id": "bta:504208", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?bta:504208", "resource": "KEGG Pathway" } ], "orthologs": [ { "uniprot_canonical_ac": "A0A4X1VYW7-1", "protein_name": "G protein-coupled receptor 85", "gene_name": "GPR85", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MANYSHAADNILQNLSPLTAFLKLTSLGFIIGVSVVGNLLISILLVKDKTLHRAPYYFLLDLCCSDILRSAICFPFVFNSVKNGSTWTYGTLTCKVIAFLGVLSCFHTAFMLFCISVTRYLAIAHHRFYTKRLTFWTCLAVICMVWTLSVAMAFPPVLDVGTYSFIREEDQCTFQHRSFRANDSLGFMLLLALILLATQLVYLKLIFFVHDRRKMKPVQFVAAVSQNWTFHGPGASGQAAANWLAGFGRGPTPPTLLGIRQNANTTGRRRLLVLDEFKMEKRISRMFYIMTFLFLTLWGPYLVACYWRVFARGPVVPGGFLTAAVWMSFAQAGINPFVCIFSNRELRRCFSTTLLYCRKSRLPREPYCVI", "length": 370 }, "evidence": [ { "id": "G3N1Y5", "url": "https://omabrowser.org/oma/group/G3N1Y5/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "E1BXX3-1", "protein_name": "G protein-coupled receptor 85", "gene_name": "GPR85", "tax_id": 9031, "organism": "Gallus gallus", "sequence": { "sequence": "MANYSHAADNILQNLSPLTAFLKLTSLGFIIGVSVVGNLLISILLVKDKTLHRAPYYFLLDLCCSDILRSAICFPFVFTSVKNGSTWTYGTLTCKVIAFLGVLSCFHTAFMLFCISVTRYLAIAHHRFYTKRLTFWTCLAVICMVWTLSVAMAFPPVLDVGTYSFIREEDQCTFQHRSFRANDSLGFMLLLALILLATQLVYLKLIFFVHDRRKMKPVQFVAAVSQNWTFHGPGASGQAAANWLAGFGRGPTPPTLLGIRQNANTTGRRRLLVLDEFKMEKRISRMFYIMTFLFLTLWGPYLVACYWRVFARGPVVPGGFLTAAVWMSFAQAGINPFVCIFSNRELRRCFSTTLLYCRKSRLPREPYCVI", "length": 370 }, "evidence": [ { "id": "G3N1Y5", "url": "https://omabrowser.org/oma/group/G3N1Y5/", "database": "OMA" } ], "glygen_name": "Chicken", "common_name": "Chicken" }, { "uniprot_canonical_ac": "G3GW31-1", "protein_name": "Probable G-protein coupled receptor 85", "gene_name": "Gpr85", "tax_id": 10029, "organism": "Cricetulus griseus", "sequence": { "sequence": "MANYSHAADNILQNLSPLTAFLKLTSLGFIIGVSVVGNLLISILLVKDKTLHRAPYYFLLDLCCSDILRSAICFPFVFNSVKNGSSWTYGTLTCKVIAFLGVLSCFHTAFMLFCISVTRYLAIAHHRFYTKRLTFWTCLAVICMVWTLSVAMAFPPVLDVGTYSFIREEDQCTFQHRSFRANDSLGFMLLLALILLATQLVYLKLIFFVHDRRKMKPVQFVAAVSQNWTFHGPGASGQAAANWLAGFGRGPTPPTLLGIRQNANTTGRRRLLVLDEFKMEKRISRMFYIMTFLFLTLWGPYLVACYWRVFARGPVVPGGFLTAAVWMSFAQAGINPFVCIFSNRELRRCFSTTLLYCRKSRLPREPYCVI", "length": 370 }, "evidence": [ { "id": "G3N1Y5", "url": "https://omabrowser.org/oma/group/G3N1Y5/", "database": "OMA" } ], "glygen_name": "Hamster", "common_name": "Chinese hamster" }, { "uniprot_canonical_ac": "P60893-1", "protein_name": "Probable G protein-coupled receptor 85", "gene_name": "GPR85", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MANYSHAADNILQNLSPLTAFLKLTSLGFIIGVSVVGNLLISILLVKDKTLHRAPYYFLLDLCCSDILRSAICFPFVFNSVKNGSTWTYGTLTCKVIAFLGVLSCFHTAFMLFCISVTRYLAIAHHRFYTKRLTFWTCLAVICMVWTLSVAMAFPPVLDVGTYSFIREEDQCTFQHRSFRANDSLGFMLLLALILLATQLVYLKLIFFVHDRRKMKPVQFVAAVSQNWTFHGPGASGQAAANWLAGFGRGPTPPTLLGIRQNANTTGRRRLLVLDEFKMEKRISRMFYIMTFLFLTLWGPYLVACYWRVFARGPVVPGGFLTAAVWMSFAQAGINPFVCIFSNRELRRCFSTTLLYCRKSRLPREPYCVI", "length": 370 }, "evidence": [ { "id": "G3N1Y5", "url": "https://omabrowser.org/oma/group/G3N1Y5/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "P60894-1", "protein_name": "Probable G protein-coupled receptor 85", "gene_name": "Gpr85", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": 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"MQDAAAGGPPGLGGGGPPEERTDCIICCSAYDLSGHLPRRLYCGHTFCQACVRRLDTPAPEQRWIPCPQCRQSTPTPRGGVAMLDLDLAAFLAVKAEREPARLEPLPLTSLKGSAITRQPAGLCPALGPQPHFPQPRYCCWGCGSLCCPPLGSPEV", "length": 156 }, "evidence": [ { "id": "G3N2A0", "url": "https://omabrowser.org/oma/group/G3N2A0/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "Q3UIW8-1", "protein_name": "RING finger protein 224", "gene_name": "Rnf224", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MLQPEGLYALEEGTALTASRNDCIICYSAYDLSVHLPRRLYCGHTFCQACMQRLDMPAHEQHWIPCPQCRQSTPVPRGGVTMLDLDLAAFLAVKAEREPSKIEPRSSVPLKISTTITQQPAGLYPTLGPQPHFPQPGCCCWGWGRLCWYPPGNPEV", "length": 156 }, "evidence": [ { "id": "G3N2A0", "url": "https://omabrowser.org/oma/group/G3N2A0/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" } ], "go_annotation": { "categories": [ { "name": "Molecular Function", "total": 1, "go_terms": [ { "name": "zinc ion binding", "id": "GO:0008270", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008270", "evidence": [ { "database": "UniProtKB", "id": "G3N2A0", "url": "https://www.uniprot.org/uniprotkb/G3N2A0" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [ { "pdb_id": "AF-G3N2A0-F1", "pdb_chain": "global", "start_pos": 1, "end_pos": 156, "overlap": "1.0", "method": "AlphaFold", "type": "alphafold", "resolution": -1.0, "url": "https://data.glygen.org/ln2downloads/pdb/current/AF-G3N2A0-F1.pdb", "url_external": "https://alphafold.ebi.ac.uk/entry/G3N2A0" } ], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "G3N2A0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3N2A0" }, { "id": "PS50089", "database": "PROSITE", "url": "https://prosite.expasy.org/PS50089" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "RING-type", "eco_id": "ECO_0000259", "start_pos": 23, "end_pos": 70, "start_aa": "Cys", "end_aa": "Arg", "glycosite_overlap": [] } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "homologset.oma", "label": "OMA Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ], "tool_support": { "graph_view": "yes" } }, { "uniprot_canonical_ac": "G3N2G3-1", "uniprot_ac": "G3N2G3", "uniprot_id": "G3N2G3_BOVIN", "mass": { "chemical_mass": 82170.0, "monoisotopic_mass": 82170.0 }, "refseq": { "ac": "XP_005207872", "name": "G protein-regulated inducer of neurite outgrowth 3", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_005207872" }, "gene_names": [ { "name": "GPRIN3", "type": "recommended", "evidence": [ { "id": "G3N2G3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3N2G3" } ] }, { "name": "GPRIN3", "type": "synonym", "evidence": [ { "id": "XP_005207872", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_005207872" } ] } ], "protein_names": [ { "name": "G protein-regulated inducer of neurite outgrowth 3", "type": "synonym", "evidence": [ { "id": "XP_005207872", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_005207872" } ] }, { "name": "GPRIN family member 3", "type": "synonym", "evidence": [ { "id": "G3N2G3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3N2G3/entry#names_and_taxonomy" } ] } ], "function": [ { "annotation": "May be involved in neurite outgrowth.", "evidence": [ { "database": "UniProtKB", "id": "G3N2G3", "url": "https://www.uniprot.org/uniprotkb/G3N2G3#function" }, { "database": "UniProtKB", "id": "ARBA00002358", "url": "https://www.uniprot.org/uniprotkb/ARBA00002358#function" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Bos taurus", "taxid": 9913, "evidence": [ { "database": "UniProtKB", "id": "G3N2G3", "url": "https://www.uniprot.org/uniprotkb/G3N2G3" } ], "common_name": "Bovine", "glygen_name": "Bovine", "reference_species": "Bos taurus [9913]" } ], "gene": [ { "name": "GPRIN3", "url": "https://www.uniprot.org/uniprotkb/G3N2G3", "locus": { "chromosome": "6", "start_pos": 35574565, "end_pos": 35496594, "strand": "-", "evidence": [ { "database": "Ensembl Gene", "id": "ENSBTAG00000045966", "url": "https://www.ensembl.org/id/ENSBTAG00000045966" } ] } } ], "crossref": [ { "id": "ENSBTAG00000045966", "url": "https://bgee.org/?page=gene&gene_id=ENSBTAG00000045966", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "517995", "url": "https://www.ncbi.nlm.nih.gov/gene/517995", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR026646", "url": "https://www.ebi.ac.uk/interpro/entry/IPR026646", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR032745", "url": "https://www.ebi.ac.uk/interpro/entry/IPR032745", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "bta:517995", "url": "https://www.genome.jp/dbget-bin/www_bget?bta:517995", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "EQLHIIY", "url": "https://omabrowser.org/oma/group/EQLHIIY/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "G3N2G3", "url": "https://www.orthodb.org/?gene=G3N2G3", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR15718", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR15718", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR15718:SF6", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR15718:SF6", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF15235", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF15235", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "XP_005207872", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_005207872", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "G3N2G3", "url": "https://www.uniprot.org/uniprotkb/G3N2G3", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "G3N2G3-1", "url": "https://www.uniprot.org/uniprotkb/G3N2G3-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MGTVPDPLRSAKTSLIAASGEEEGLGEVQVASPQPRPEVLSENTNGLSSTPAEPDLSPRTAAKALMQASEHVPTQAAMSSPDIVSEVGKASPTLNSPGNTQLSGGREPTAPALCSAAGKDLIPATFTMPANQHIHPVVPGNQPHASPQSGPEDTLVKSQRTADGGQPEKSSCPVVVICGKDQMPCDFPSQETMQGIVQTEDTAARSFSPTSATVGGPEAERQQAVCTSQTRSCGSPTGEDGCSGNKPPSAATSDTQAMTSVIPQPSHLPSNGSMFPPDPEKVPLAAQPQVSRFKEASTMTSQAENEIKKTPPRAQQDAEVQAVASVQSRSASTSPSILAAFLKETPAPERFEQEQLRVICHGSANHTLELSENTLDPREAGQCRDLMPAVHIQTATAVSAAFQGENKSGSLPGEVLKTSAINVSSSDAQETCKQDGKSAGMTLAGQELTFRQLSGTTSTSLKASPSDQTSLSAGRQVETGHGLGKCETKPSEFAVATTSGHKPDPDCKLSDYCGPASRADQSRSLDLTNQGDAREKKLASPQIMKEQESPGIDILEVRARAEAKSLLLNPKSQESGGVASGASPTPSPVRRSQEGTGEENRQTKTAASLSLPSDAIGDSSPGSGKRTPSRSVKASPRRASRVSEFLKEQKLNVTAAAAQVGLTPGEKKKQLSADSKLQLKQSKRVRDVVWDEQGMTWEVYGASLDPESLGIAIQNHLQRQIREHEKLIKAQSGQSRRSISSDTSSNKKLKGRQHSVFQSMLQNFRRPTCCIRPAPSSVLD", "length": 780, "header": "tr|G3N2G3-1|G3N2G3_BOVIN Isoform 1 of GPRIN family member 3 OS=Bos taurus OX=9913 GN=GPRIN3 PE=4 SV=1 CANONICAL=G3N2G3-1" }, "isoforms": [ { "isoform_ac": "G3N2G3-1", "url": "https://www.uniprot.org/uniprotkb/G3N2G3/entry", "sequence": { "sequence": "MGTVPDPLRSAKTSLIAASGEEEGLGEVQVASPQPRPEVLSENTNGLSSTPAEPDLSPRTAAKALMQASEHVPTQAAMSSPDIVSEVGKASPTLNSPGNTQLSGGREPTAPALCSAAGKDLIPATFTMPANQHIHPVVPGNQPHASPQSGPEDTLVKSQRTADGGQPEKSSCPVVVICGKDQMPCDFPSQETMQGIVQTEDTAARSFSPTSATVGGPEAERQQAVCTSQTRSCGSPTGEDGCSGNKPPSAATSDTQAMTSVIPQPSHLPSNGSMFPPDPEKVPLAAQPQVSRFKEASTMTSQAENEIKKTPPRAQQDAEVQAVASVQSRSASTSPSILAAFLKETPAPERFEQEQLRVICHGSANHTLELSENTLDPREAGQCRDLMPAVHIQTATAVSAAFQGENKSGSLPGEVLKTSAINVSSSDAQETCKQDGKSAGMTLAGQELTFRQLSGTTSTSLKASPSDQTSLSAGRQVETGHGLGKCETKPSEFAVATTSGHKPDPDCKLSDYCGPASRADQSRSLDLTNQGDAREKKLASPQIMKEQESPGIDILEVRARAEAKSLLLNPKSQESGGVASGASPTPSPVRRSQEGTGEENRQTKTAASLSLPSDAIGDSSPGSGKRTPSRSVKASPRRASRVSEFLKEQKLNVTAAAAQVGLTPGEKKKQLSADSKLQLKQSKRVRDVVWDEQGMTWEVYGASLDPESLGIAIQNHLQRQIREHEKLIKAQSGQSRRSISSDTSSNKKLKGRQHSVFQSMLQNFRRPTCCIRPAPSSVLD", "length": 780, "header": "tr|G3N2G3-1|G3N2G3_BOVIN Isoform 1 of GPRIN family member 3 OS=Bos taurus OX=9913 GN=GPRIN3 PE=4 SV=1 CANONICAL=G3N2G3-1" }, "locus": { "chromosome": "6", "start_pos": 35565992, "end_pos": 35563653, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000128732.2", "url": "https://www.ensembl.org/id/ENSBTAT00000128732.2" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000081895.1", "url": "https://www.ensembl.org/id/ENSBTAP00000081895.1" } ] } } ], "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "other", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 585, "start_aa": "Thr", "end_pos": 585, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr585", "evidence": [ { "id": "", "database": "GlyGen", "url": "https://data.glygen.org/" } ], "filter_code": "000000000000000010000.00000000001000.0.01000" } ], "phosphorylation": [], "glycation": [], "keywords": [ "glycoprotein", "glycoprotein_predicted" ], "publication": [], "pathway": [ { "id": "bta:517995", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?bta:517995", "resource": "KEGG Pathway" } ], "orthologs": [ { "uniprot_canonical_ac": "A0ABK0LZG4-1", "protein_name": "GPRIN family member 3", "gene_name": "Gprin3", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MHRRLETVFKTQCQASSSEDSSLCLPSDSDYFPVENILGTDTGVLLERDPMGTVPDPLRVTKASIVAASRKEESPGELQSVSPQPAQPDKNVSGIGNAPAELSLRLSSAAPALMQACVHESSPQDMTSPGMLNEVEQVSPKNNTPDDSQPQGSKESAAPDANATAKKELTSAPFLMSAVQHMHHAIRNDPPNTSTCPVPEDSLVKSEANSDREKPEKSSCPTRVTCCSSKNKVFCDFPSPENSQGIVQTPDRAVRIHSSPSADRPEGEEQKAINSTTVVSSEPLARGECSENRQPSDTVLDTTDEKSENPPLSPLTSREATCSSEARQVQLPTQHPTSRFKEASTMTCQAESEAKEVPGRAWQDAEVQAVASVESRSVSTSPSILPAFLKENPALEQENGQEQLRVICHDKGSGSRLLELSNSMVDPQESRQCPSIVPQVHIQAPVATSTAFKGGCKPANQPAEGLKSPLVHVASSQTPDTEEDLRSSTSKEATSRELTGTNLGSQKATTIAQISVLAGSQAEISLGLGNSGLRAPELVEKIANDHKTEPDCKLSNSRGGVNEDQPLESLDPTDKRDAKDKNPASPLIVKDHAPGATSTPDAKTLLLNPKSHGSEGPEVSPAPSPGRKSTVEEHRQTKTVTSLSLPSDGTGDSSPGSGKRTPSRSVKASPRRASRVSEFLKELNVTAAAAQVGLTPGEKKKQLGAESKLQLKQSKRVRDVVWDDQGMTWEVYGASLDPESLGVAIQNHLQRQIREHEKLVKTQSGQTRRSISSDSSSSKKLKGRQQGVLQSMLQNFRRPNCCVRPAPSSVLD", "length": 812 }, "evidence": [ { "id": "G3N2G3", "url": "https://omabrowser.org/oma/group/G3N2G3/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "Q6ZVF9-1", "protein_name": "G protein-regulated inducer of neurite outgrowth 3", "gene_name": "GPRIN3", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MGTVPDPLRSAKTSLIAASGKEDDLGEPQAASPRHRPALLCKNANGFSGAPAEPDLSPRAAAEALMQVCEHETTQPDMSSPGVFNEVQKAPATFNSPGNPQLPGSSQPAASAPSSAAGRDLIHTPLTMPANQHTCQSIPGDQPNAITSSMPEDSLMRSQRTSNREQPEKPSCPVGGVLSSSKDQVSCEFPSPETIQGTVQTPVTAARVVSHSSSPVGGPEGERQGAICDSEMRSCKPLTRESGCSENKQPSVTASGPQGTTSVTPQPTPLTSEPSACPPGPEKVPLPAQRQMSRFKEASTMTNQAESEIKEVPSRAWQDAEVQAVASVESRSVSTSPSILTAFLKESRAPEHFEQEQLRVICHSSGSHTLELSDSTLAPQESSQCPGIMPQVHIQAAAAESTAFQRENKLASLPGGVLKTSSINLVSSNAQHTCKEDGRLAGMTPVREESTAKKLAGTNSSSLKATAIDQISISACSQAETSYGLGKFETRPSEFAEKTTNGHKTDPDCKLSDSCGSISKADHSGSLDPTNKGDAREKKPASPQVVKEKESTGTDTSDAKTLLLNPKSQESGGTESAANPTPSPIRKNQESTLEENRQTKTATSLSLPSDPMGDSSPGSGKKTPSRSVKASPRRPSRVSEFLKEQKLNVTAAAAQVGLTPGDKKKQLGADSKLQLKQSKRVRDVVWDEQGMTWEVYGASLDAESLGIAIQNHLQRQIREHEKLIKTQNSQTRRSISSDTSSNKKLRGRQHSVFQSMLQNFRRPNCCVRPAPSSVLD", "length": 776 }, "evidence": [ { "id": "G3N2G3", "url": "https://omabrowser.org/oma/group/G3N2G3/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "Q8BWS5-1", "protein_name": "G protein-regulated inducer of neurite outgrowth 3", "gene_name": "Gprin3", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MGTVPDPLRVTKASIVAASGKEESRGESQSVSPQPAQPDNNASGIGNVPAELSLQLSAAAQALMQACVSESSQQDMASPGVFSEGEPVSPKQKTPDDFLLHGSKESAAPGLNATAQKELISAPCLISVVQHTHHAIQRDAPNTSTCAVPEGSLVKSEANSNGENPEKPGCPARVTCCSSKNQEGLCDFPSPENSQGILQTPDIASPSADRPEGEGQKVINNITAVSSEPPVREGCSENKQPSATALNTTAERSENPPPSHLTSKGATCSSEARQALLPAQYPVSRFKEASTMTCQAESGAKEVSGRAWQDAEVQAVASVESRSVSTSPSILPAYLKENPAPELENGQEQLRVICHGKGSGNHLLELSNSMVDSQESRQCPSIVPQVHIQAATATPAAFKGGCKPANQPAEGLKSPLIHVTSSQNTETEEDLRLSASKEATSRQPEGTNPDFQKANAIGQISLPAGSQAEINQGLWNSGPREPEIVVKTAKDHKAESSCKPSNSGGGANKDYPPESLDPTDKKGAKDKKPASPLIVKDHAPGATSTLDAKTLLLNPKSQVKEGEGPEVSPAPSPGRKSQQNTLEELRQPKTVMSLSLPSDGTGDSSPGSGKRTPSLSVKASPRRGSRVSEFLKELSVTAAAAQVGLTPGEKKKQLGADSKLHLKQSKRVRDVVWDDQGMTWEVYGASLDPESLGVAIQNHLQRQIREHEKIVKTQSGQTRRSISSDSSSSKKLKGRQHGVLQSMLQNFRRPNCCVRPAPSSVLD", "length": 763 }, "evidence": [ { "id": "G3N2G3", "url": "https://omabrowser.org/oma/group/G3N2G3/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" } ], "go_annotation": { "categories": [ { "name": "Cellular 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"MENEDGYMTLKIKNRFEPRKKSKDFALYLQCYCLMLVLGCIGILIFMMAVIGLNFWNREMDFLQKANITSLAGNNYVCPSDWLLNQGKCYRFSTFSKTWNESQRDCLKLQAHLPVIQNSKELKFIQKSLKSGQPSWLGLCITSPGKQWVWINEHLFVEQEIFSVIGPIDNMSCAVITRNQVYSEDCDSKFNGICQRDAV", "length": 199, "header": "tr|G3N2I5-1|G3N2I5_BOVIN Isoform 1 of Killer cell lectin like receptor F2 OS=Bos taurus OX=9913 GN=KLRF2 PE=4 SV=3 CANONICAL=G3N2I5-1" }, "locus": { "chromosome": "5", "start_pos": 100059978, "end_pos": 100044289, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000064777.3", "url": "https://www.ensembl.org/id/ENSBTAT00000064777.3" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000056100.3", "url": "https://www.ensembl.org/id/ENSBTAP00000056100.3" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [], "orthologs": [], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 2, "go_terms": [ { "name": "plasma membrane", "id": "GO:0005886", 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"ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [ { "pdb_id": "AF-G3N2I5-F1", "pdb_chain": "global", "start_pos": 1, "end_pos": 199, "overlap": "1.0", "method": "AlphaFold", "type": "alphafold", "resolution": -1.0, "url": "https://data.glygen.org/ln2downloads/pdb/current/AF-G3N2I5-F1.pdb", "url_external": "https://alphafold.ebi.ac.uk/entry/G3N2I5" } ], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "G3N2I5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3N2I5" }, { "id": "PS50041", "database": "PROSITE", "url": "https://prosite.expasy.org/PS50041" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "C-type lectin", "eco_id": "ECO_0000259", "start_pos": 85, "end_pos": 195, "start_aa": "Asn", "end_aa": "Gln", "glycosite_overlap": [] } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 100, "end_pos": 102 }, { "start_pos": 170, "end_pos": 172 }, { "start_pos": 67, "end_pos": 69 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { 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The olfactory receptor proteins are members of a large family of G-protein-coupled receptors (GPCR) arising from single coding-exon genes. Olfactory receptors share a 7-transmembrane domain structure with many neurotransmitter and hormone receptors and are responsible for the recognition and G protein-mediated transduction of odorant signals. The olfactory receptor gene family is the largest in the genome. 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"database": "Ensembl Gene", "id": "ENSBTAG00000047362", "url": "https://www.ensembl.org/id/ENSBTAG00000047362" } ] } } ], "crossref": [ { "id": "G3N2L2", "url": "https://alphafold.ebi.ac.uk/entry/G3N2L2", "database": "AlphaFoldDB", "categories": [] }, { "id": "ENSBTAG00000047362", "url": "https://bgee.org/?page=gene&gene_id=ENSBTAG00000047362", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "cd16229", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd16229", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "IPR002048", "url": "https://www.ebi.ac.uk/interpro/entry/IPR002048", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR011992", "url": "https://www.ebi.ac.uk/interpro/entry/IPR011992", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR018247", "url": "https://www.ebi.ac.uk/interpro/entry/IPR018247", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR027241", "url": "https://www.ebi.ac.uk/interpro/entry/IPR027241", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "DRPGFQY", "url": "https://omabrowser.org/oma/group/DRPGFQY/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "PTHR10827", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR10827", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR10827:SF17", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR10827:SF17", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF13202", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF13202", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF13499", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF13499", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "R-BTA-381426", "url": "https://www.reactome.org/PathwayBrowser/#R-BTA-381426", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "R-BTA-8957275", "url": "https://www.reactome.org/PathwayBrowser/#R-BTA-8957275", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "G3N2L2", "url": "https://www.uniprot.org/uniprotkb/G3N2L2", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "G3N2L2-1", "url": "https://www.uniprot.org/uniprotkb/G3N2L2-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MARGGRGRHLGLALGLLLALLLAPPALWAKPTVRKERVVRPDSDLGERPAEDNQSFQYDHEAFLGKEDSKTFDQLTSEESKERLGKIVDRIDSDGDGFVTTEELKTWIKRVQKRYIYDNVAKVWKDYDRDKDDKISWEEYKQATYGYYLGNPTEFQDTSDHHTFKKMLPRDERRFKAADLDSDQTATREEFTAFLHPEEFEHMKEIVVLETLEDIDKNGDGFVDQDEYIADMFSHEESGPEPDWVLSEREQFNEFRDLNKDGKLDKDEIRHWILPQDYDHAQAEARHLVYESDKNKDEKLTKEEILDNWNMFVGSQATNYGEDLTKNHDEL", "length": 331, "header": "tr|G3N2L2-1|G3N2L2_BOVIN Isoform 1 of Reticulocalbin-1 OS=Bos taurus OX=9913 GN=RCN1 PE=1 SV=2 CANONICAL=G3N2L2-1" }, "isoforms": [ { "isoform_ac": "G3N2L2-1", "url": "https://www.uniprot.org/uniprotkb/G3N2L2/entry", "sequence": { "sequence": "MARGGRGRHLGLALGLLLALLLAPPALWAKPTVRKERVVRPDSDLGERPAEDNQSFQYDHEAFLGKEDSKTFDQLTSEESKERLGKIVDRIDSDGDGFVTTEELKTWIKRVQKRYIYDNVAKVWKDYDRDKDDKISWEEYKQATYGYYLGNPTEFQDTSDHHTFKKMLPRDERRFKAADLDSDQTATREEFTAFLHPEEFEHMKEIVVLETLEDIDKNGDGFVDQDEYIADMFSHEESGPEPDWVLSEREQFNEFRDLNKDGKLDKDEIRHWILPQDYDHAQAEARHLVYESDKNKDEKLTKEEILDNWNMFVGSQATNYGEDLTKNHDEL", "length": 331, "header": "tr|G3N2L2-1|G3N2L2_BOVIN Isoform 1 of Reticulocalbin-1 OS=Bos taurus OX=9913 GN=RCN1 PE=1 SV=2 CANONICAL=G3N2L2-1" }, "locus": { "chromosome": "15", "start_pos": 62866458, "end_pos": 62854527, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000063521.3", "url": "https://www.ensembl.org/id/ENSBTAT00000063521.3" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000056127.2", "url": "https://www.ensembl.org/id/ENSBTAP00000056127.2" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [ { "id": "R-BTA-381426", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-BTA-381426", "resource": "Reactome", "description": "Regulation of Insulin-like Growth Factor (IGF) transport and uptake by Insulin-like Growth Factor Binding Proteins (IGFBPs)" }, { "id": "R-BTA-8957275", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-BTA-8957275", "resource": "Reactome", "description": "Post-translational protein phosphorylation" } ], "orthologs": [ { "uniprot_canonical_ac": "D3ZUB0-1", "protein_name": "Reticulocalbin-1", "gene_name": "Rcn1", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MARGGRLGLALGLLLALVLALRAKPTVRKERVVRPDSELGERPPEDNQSFQYDHEAFLGKEDSKTFDQLSPDESKERLGKIVDRIDSDGDGLVTTEELKVWIKRVQKRYIYDNVAKVWKDYDRDKDEKISWEEYKQATYGYYLGNPAEFQDSSDHHTFKKMLPRDERRFKASDLDGDLTATREEFTAFLHPEEFEHMKEIVVLETLEDIDKNGDGFVDQDEYIADMFSHEDNGPEPDWVLSEREQFNDFRDLNKDGKLDKDEIRHWILPQDYDHAQAEARHLVYESDKNKDEMLTKEEILDNWNMFVGSQATNYGEDLTKNHDEL", "length": 325 }, "evidence": [ { "id": "G3N2L2", "url": "https://omabrowser.org/oma/group/G3N2L2/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "E1BXF4-1", "protein_name": "Reticulocalbin 1", "gene_name": "RCN1", "tax_id": 9031, "organism": "Gallus gallus", "sequence": { "sequence": "MGGGAGRCPAALLLLALPLLALPGGLGKPTAWQERARPGTAQQHEDAPSFQYDHEAFLGKEEARSFDQLSPEESQERLGKIVDRIDENKDGYLTTEELKNWIKRVQKRYIYENVAKVWKDYDTNKDNKITWEEYKQATYGYYLENPEEFQDATDRHSFKKMLPRDERRFKTADLDGDSAATREEFTAFLHPEEFEHMKDIVVLETLEDIDKNEDGFVDQDEYIADMFANEEGGPEPDWVTTEREQFSDFRDLNKDGKMDKEEIQHWILPQDYDHALAEARHLVYESDVDKDQKLTKEEVLDNWNMFVGSQATNYGEDLTRNHDEL", "length": 325 }, "evidence": [ { "id": "G3N2L2", "url": "https://omabrowser.org/oma/group/G3N2L2/", "database": "OMA" } ], "glygen_name": "Chicken", "common_name": "Chicken" }, { "uniprot_canonical_ac": "F1R369-1", "protein_name": "Reticulocalbin-1", "gene_name": "rcn1", "tax_id": 7955, "organism": "Danio rerio", "sequence": { "sequence": "MEVSTYLWLLSLCTSLVQGKPTLRKERVHHEPELSRQTHEDNQSYQYDHEAFLGKEEATTFDQLTPEESKARLGKIVERIDSNVDGFITTDELKAWIKRVQKRYVYENVAKVWTDYDLNKDNKISWDEYKQATYGYYLANPEEFEDATDQFSFKKMLPRDERRFKTADLDGNLAADKEEFTAFLHPEEFAHMQEIVVLETLEDIDKNGDGHVDEDEYIADMFAHEDAGPEPDWVRTERDQFSDFRDLNKDGKMDLEEIRHWILPQDYDHAQAEARHLVYESDTDKDQMLSKEEILENWNMFVGSQATNYGEDLTRNHDEL", "length": 320 }, "evidence": [ { "id": "G3N2L2", "url": "https://omabrowser.org/oma/group/G3N2L2/", "database": "OMA" } ], "glygen_name": "Zebrafish", "common_name": "Zebrafish" }, { "uniprot_canonical_ac": "Q05186-1", "protein_name": "Reticulocalbin-1", "gene_name": "Rcn1", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MARGGRLGLALGLLLALVLALRAKPTVRKERVVRPDSELGERPPEDNQSFQYDHEAFLGKEDSKTFDQLSPDESKERLGKIVDRIDSDGDGLVTTEELKLWIKRVQKRYIYDNVAKVWKDYDRDKDEKISWEEYKQATYGYYLGNPAEFHDSSDHHTFKKMLPRDERRFKASDLDGDLTATREEFTAFLHPEEFEHMKEIVVLETLEDIDKNGDGFVDQDEYIADMFSHEDNGPEPDWVLSEREQFNDFRDLNKDGKLDKDEIRHWILPQDYDHAQAEARHLVYESDKNKDEMLTKEEILDNWNMFVGSQATNYGEDLTKNHDEL", "length": 325 }, "evidence": [ { "id": "G3N2L2", "url": "https://omabrowser.org/oma/group/G3N2L2/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q15293-1", "protein_name": "Reticulocalbin-1", "gene_name": "RCN1", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MARGGRGRRLGLALGLLLALVLAPRVLRAKPTVRKERVVRPDSELGERPPEDNQSFQYDHEAFLGKEDSKTFDQLTPDESKERLGKIVDRIDNDGDGFVTTEELKTWIKRVQKRYIFDNVAKVWKDYDRDKDDKISWEEYKQATYGYYLGNPAEFHDSSDHHTFKKMLPRDERRFKAADLNGDLTATREEFTAFLHPEEFEHMKEIVVLETLEDIDKNGDGFVDQDEYIADMFSHEENGPEPDWVLSEREQFNEFRDLNKDGKLDKDEIRHWILPQDYDHAQAEARHLVYESDKNKDEKLTKEEILENWNMFVGSQATNYGEDLTKNHDEL", "length": 331 }, "evidence": [ { "id": "G3N2L2", "url": "https://omabrowser.org/oma/group/G3N2L2/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" } ], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 2, "go_terms": [ { "name": "endoplasmic reticulum", "id": "GO:0005783", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005783", "evidence": [ { "database": "UniProtKB", "id": "G3N2L2", "url": "https://www.uniprot.org/uniprotkb/G3N2L2" } ], "pmid": "" }, { "name": "endoplasmic reticulum lumen", "id": "GO:0005788", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005788", "evidence": [ { "database": "UniProtKB", "id": "G3N2L2", "url": "https://www.uniprot.org/uniprotkb/G3N2L2" } ], "pmid": "" } ] }, { "name": "Molecular Function", "total": 1, "go_terms": [ { "name": "calcium ion binding", "id": "GO:0005509", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005509", "evidence": [ { "database": "UniProtKB", "id": "G3N2L2", "url": "https://www.uniprot.org/uniprotkb/G3N2L2" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 53, "end_pos": 55, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [ { "pdb_id": "AF-G3N2L2-F1", "pdb_chain": "global", "start_pos": 1, "end_pos": 331, "overlap": "1.0", "method": "AlphaFold", "type": "alphafold", "resolution": -1.0, "url": "https://data.glygen.org/ln2downloads/pdb/current/AF-G3N2L2-F1.pdb", "url_external": "https://alphafold.ebi.ac.uk/entry/G3N2L2" } ], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "G3N2L2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3N2L2" }, { "id": "PS50222", "database": "PROSITE", "url": "https://prosite.expasy.org/PS50222" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "EF-hand", "eco_id": "ECO_0000259", "start_pos": 79, "end_pos": 114, "start_aa": "Glu", "end_aa": "Arg", "glycosite_overlap": [] } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "homologset.oma", "label": "OMA Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 53, "end_pos": 55 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ], "tool_support": { "graph_view": "yes" } }, { "uniprot_canonical_ac": "G3N2M8-1", "uniprot_ac": "G3N2M8", "uniprot_id": "G3N2M8_BOVIN", "mass": { "chemical_mass": 79469.0, "monoisotopic_mass": 79469.0 }, "refseq": {}, "gene_names": [ { "name": "SAMD15", "type": "recommended", "evidence": [ { "id": "G3N2M8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3N2M8" } ] } ], "protein_names": [ { "name": "Sterile alpha motif domain containing 15", "type": "synonym", "evidence": [ { "id": "G3N2M8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3N2M8/entry#names_and_taxonomy" } ] } ], "function": [], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Bos taurus", "taxid": 9913, "evidence": [ { "database": "UniProtKB", "id": "G3N2M8", "url": "https://www.uniprot.org/uniprotkb/G3N2M8" } ], "common_name": "Bovine", "glygen_name": "Bovine", "reference_species": "Bos taurus [9913]" } ], "gene": [ { "name": "SAMD15", "url": "https://www.uniprot.org/uniprotkb/G3N2M8", "locus": { "chromosome": "10", "start_pos": 88592664, "end_pos": 88580543, "strand": "-", "evidence": [ { "database": "Ensembl Gene", "id": "ENSBTAG00000020471", "url": "https://www.ensembl.org/id/ENSBTAG00000020471" } ] } } ], "crossref": [ { "id": "G3N2M8", "url": "https://alphafold.ebi.ac.uk/entry/G3N2M8", "database": "AlphaFoldDB", "categories": [] }, { "id": "ENSBTAG00000020471", "url": "https://bgee.org/?page=gene&gene_id=ENSBTAG00000020471", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "cd09530", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd09530", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "IPR001660", "url": "https://www.ebi.ac.uk/interpro/entry/IPR001660", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR013761", "url": "https://www.ebi.ac.uk/interpro/entry/IPR013761", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "G3N2M8", "url": "https://www.orthodb.org/?gene=G3N2M8", "database": "OrthoDB", "categories": [ "Protein 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"G3N2W3-1", "url": "https://www.uniprot.org/uniprotkb/G3N2W3/entry", "sequence": { "sequence": "MPRGQKSKHRAREKRRQTQTETQGVHDQATTSGGEETTSSSLPDSESAPSSSSAAGTPKGPQGAHGTTSAAAGAIRKRSGVSGAARSRSGVGAEGQVQEGENSSQASAAAESSHTDILTRKAELLVPYMLYKYKMRELIKRSEILKEINRRYKEQYPEILRRASEHMEMVFGLVLKEIRPNSHCYTLVSNLDLSDSESMRGDWGLPKNGLLMPLLGVIYLNGNHAPEEKIWKFLNMLGIYDGRSHFIFGEPRKLITEDLVREEYLEYRQVPGSDPPRYEFLWGPKALTEMSKTKVLQFLAKVKDSVHPAFLLQYEEAWREEVETTGARSEARAGTSASTRPGTAASAAACSSASTRPGTAASTSAGPSALATACPRAASSRSSRP", "length": 385, "header": "tr|G3N2W3-1|G3N2W3_BOVIN Isoform 1 of MAGE domain-containing protein OS=Bos taurus OX=9913 GN=LOC788328 PE=4 SV=2 CANONICAL=G3N2W3-1" }, "locus": { "chromosome": "NKLS02001286.1", "start_pos": 9203, "end_pos": 8049, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000065515.3", "url": "https://www.ensembl.org/id/ENSBTAT00000065515.3" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000056233.2", "url": "https://www.ensembl.org/id/ENSBTAP00000056233.2" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [ { "id": "bta:788328", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?bta:788328", "resource": "KEGG Pathway" } ], "orthologs": [ { "uniprot_canonical_ac": "O15479-1", "protein_name": "Melanoma-associated antigen B2", "gene_name": "MAGEB2", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MPRGQKSKLRAREKRRKARDETRGLNVPQVTEAEEEEAPCCSSSVSGGAASSSPAAGIPQEPQRAPTTAAAAAAGVSSTKSKKGAKSHQGEKNASSSQASTSTKSPSEDPLTRKSGSLVQFLLYKYKIKKSVTKGEMLKIVGKRFREHFPEILKKASEGLSVVFGLELNKVNPNGHTYTFIDKVDLTDEESLLSSWDFPRRKLLMPLLGVIFLNGNSATEEEIWEFLNMLGVYDGEEHSVFGEPWKLITKDLVQEKYLEYKQVPSSDPPRFQFLWGPRAYAETSKMKVLEFLAKVNGTTPCAFPTHYEEALKDEEKAGV", "length": 319 }, "evidence": [ { "id": "G3N2W3", "url": "https://omabrowser.org/oma/group/G3N2W3/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" } ], "go_annotation": { "categories": [ { "name": "Biological Process", "total": 1, "go_terms": [ { "name": "negative regulation of transcription by RNA polymerase II", "id": "GO:0000122", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000122", "evidence": [ { "database": "UniProtKB", "id": "G3N2W3", "url": "https://www.uniprot.org/uniprotkb/G3N2W3" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 1, "go_terms": [ { "name": "nucleus", "id": "GO:0005634", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005634", "evidence": [ { "database": "UniProtKB", "id": "G3N2W3", "url": "https://www.uniprot.org/uniprotkb/G3N2W3" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 102, "end_pos": 104, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [ { "pdb_id": "AF-G3N2W3-F1", "pdb_chain": "global", "start_pos": 1, "end_pos": 385, "overlap": "1.0", "method": "AlphaFold", "type": "alphafold", "resolution": -1.0, "url": "https://data.glygen.org/ln2downloads/pdb/current/AF-G3N2W3-F1.pdb", "url_external": "https://alphafold.ebi.ac.uk/entry/G3N2W3" } ], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "G3N2W3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3N2W3" }, { "id": "PS50838", "database": "PROSITE", "url": "https://prosite.expasy.org/PS50838" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "MAGE", "eco_id": "ECO_0000259", "start_pos": 118, "end_pos": 317, "start_aa": "Leu", "end_aa": "Ala", "glycosite_overlap": [] } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "homologset.oma", "label": "OMA Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 102, "end_pos": 104 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { 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"total", "count": 0 } ], "sort_fields": [] } ], "tool_support": { "graph_view": "yes" } }, { "uniprot_canonical_ac": "G3N2Y1-1", "uniprot_ac": "G3N2Y1", "uniprot_id": "G3N2Y1_BOVIN", "mass": { "chemical_mass": 88549.0, "monoisotopic_mass": 88549.0 }, "refseq": {}, "gene_names": [ { "name": "LRRC41", "type": "recommended", "evidence": [ { "id": "G3N2Y1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3N2Y1" } ] } ], "protein_names": [ { "name": "Leucine-rich repeat-containing protein 41", "type": "recommended", "evidence": [ { "id": "G3N2Y1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3N2Y1/entry#names_and_taxonomy" } ] } ], "function": [], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Bos taurus", "taxid": 9913, "evidence": [ { "database": "UniProtKB", "id": "G3N2Y1", "url": "https://www.uniprot.org/uniprotkb/G3N2Y1" } ], "common_name": "Bovine", "glygen_name": "Bovine", "reference_species": "Bos taurus [9913]" } ], "gene": [ { "name": "LRRC41", "url": "https://www.uniprot.org/uniprotkb/G3N2Y1", "locus": { "chromosome": "3", "start_pos": 99817768, "end_pos": 99799405, "strand": "-", "evidence": [ { "database": "Ensembl Gene", "id": "ENSBTAG00000045664", "url": "https://www.ensembl.org/id/ENSBTAG00000045664" } ] } } ], "crossref": [ { "id": "G3N2Y1", "url": "https://alphafold.ebi.ac.uk/entry/G3N2Y1", "database": "AlphaFoldDB", "categories": [] }, { "id": "ENSBTAG00000045664", "url": "https://bgee.org/?page=gene&gene_id=ENSBTAG00000045664", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "IPR026137", "url": "https://www.ebi.ac.uk/interpro/entry/IPR026137", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR032675", "url": "https://www.ebi.ac.uk/interpro/entry/IPR032675", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "VVSDSWH", "url": "https://omabrowser.org/oma/group/VVSDSWH/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "G3N2Y1", "url": "https://www.orthodb.org/?gene=G3N2Y1", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "G3X7Q6", "url": "https://www.orthodb.org/?gene=G3X7Q6", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR15354", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR15354", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR15354:SF1", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR15354:SF1", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "R-BTA-8951664", "url": "https://www.reactome.org/PathwayBrowser/#R-BTA-8951664", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "R-BTA-9706019", "url": "https://www.reactome.org/PathwayBrowser/#R-BTA-9706019", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "R-BTA-983168", "url": "https://www.reactome.org/PathwayBrowser/#R-BTA-983168", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "G3N2Y1", "url": "https://www.uniprot.org/uniprotkb/G3N2Y1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "G3N2Y1-1", "url": "https://www.uniprot.org/uniprotkb/G3N2Y1-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "G3X7Q6", "url": "https://www.uniprot.org/uniprotkb/G3X7Q6", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "G3X7Q6-1", "url": "https://www.uniprot.org/uniprotkb/G3X7Q6-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MAAPEAWRARSCWFCEVAAATTMEATSREAAPAKSSASGPSAPPALFELCGRAVSAHMGVLESGVWALPGPILQSILPLLNIYYLERIEETALKKGLSTQAIWRRLWDELMKTRPSSLESVTCWRAKFMEAFFSHVLRGTIDVSSDRRLCDQRFSPLLHSSRHVRQLTICNMLQGATELVAEPNRRVLETLASSLHTLKFRHLLFSDVAAQQSLRQLLHQLIHHGAVSQVSLYSWPVPESALFILILTMSAGFWQPGPGGPPCRLCGEASRGRAPSRDEGSLLLGSRRPRRDAAERCAAALMASRRKSEAKQTARAAPATRVTRRSTQESLTAGGTDSKREPLPPATSHEAPGTKRPPSAPATTSSASASSSTSSSKRAPASSAPQPKPLKRFKRAAGKGARTRQGCGAESEDLYDFVFIVAGEKEDGEEMEIGEVACGALDGSDPSCLGLPALEASQRFRSISTLELFTVPLSTEAALTLCHLLSSWVSLESLTLSYNGLGSNIFRLLDSLRALSVQAGCRLRALHLSDLFSPLPILELTRAIVRALPLLRVLSIRVDHPSQRDNPAVPGNAGPPSNVIGDEEIPENCLEQLEMGFPRGAQPAPLLCSVLKASGSLQQLSLDSATFASPQDFGLVLQTLKEYNLTLKRLSFHDMNLADCQSEVLFLLQNLTLQEITFSFCRLFEKRPAQFLPEMVAAMKGNSTLKGLRLPGNRLGNAGLLALADVFSEDSSSSLCQLDISSNCIKPDGLLEFAKRLERWGRGAFGHLRLFQNWLDQDAVTAREAIRRLRATCHVVSDSWDSSQAFADYVSTM", "length": 813, "header": "tr|G3N2Y1-1|G3N2Y1_BOVIN Isoform 1 of Leucine-rich repeat-containing protein 41 OS=Bos taurus OX=9913 GN=LRRC41 PE=4 SV=2 CANONICAL=G3N2Y1-1" }, "isoforms": [ { "isoform_ac": "G3N2Y1-1", "url": "https://www.uniprot.org/uniprotkb/G3N2Y1/entry", "sequence": { "sequence": "MAAPEAWRARSCWFCEVAAATTMEATSREAAPAKSSASGPSAPPALFELCGRAVSAHMGVLESGVWALPGPILQSILPLLNIYYLERIEETALKKGLSTQAIWRRLWDELMKTRPSSLESVTCWRAKFMEAFFSHVLRGTIDVSSDRRLCDQRFSPLLHSSRHVRQLTICNMLQGATELVAEPNRRVLETLASSLHTLKFRHLLFSDVAAQQSLRQLLHQLIHHGAVSQVSLYSWPVPESALFILILTMSAGFWQPGPGGPPCRLCGEASRGRAPSRDEGSLLLGSRRPRRDAAERCAAALMASRRKSEAKQTARAAPATRVTRRSTQESLTAGGTDSKREPLPPATSHEAPGTKRPPSAPATTSSASASSSTSSSKRAPASSAPQPKPLKRFKRAAGKGARTRQGCGAESEDLYDFVFIVAGEKEDGEEMEIGEVACGALDGSDPSCLGLPALEASQRFRSISTLELFTVPLSTEAALTLCHLLSSWVSLESLTLSYNGLGSNIFRLLDSLRALSVQAGCRLRALHLSDLFSPLPILELTRAIVRALPLLRVLSIRVDHPSQRDNPAVPGNAGPPSNVIGDEEIPENCLEQLEMGFPRGAQPAPLLCSVLKASGSLQQLSLDSATFASPQDFGLVLQTLKEYNLTLKRLSFHDMNLADCQSEVLFLLQNLTLQEITFSFCRLFEKRPAQFLPEMVAAMKGNSTLKGLRLPGNRLGNAGLLALADVFSEDSSSSLCQLDISSNCIKPDGLLEFAKRLERWGRGAFGHLRLFQNWLDQDAVTAREAIRRLRATCHVVSDSWDSSQAFADYVSTM", "length": 813, "header": "tr|G3N2Y1-1|G3N2Y1_BOVIN Isoform 1 of Leucine-rich repeat-containing protein 41 OS=Bos taurus OX=9913 GN=LRRC41 PE=4 SV=2 CANONICAL=G3N2Y1-1" }, "locus": { "chromosome": "3", "start_pos": 99817293, "end_pos": 99799454, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000064452.2", "url": "https://www.ensembl.org/id/ENSBTAT00000064452.2" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000056252.2", "url": "https://www.ensembl.org/id/ENSBTAP00000056252.2" } ] } }, { "isoform_ac": "G3X7Q6-1", "url": "https://www.uniprot.org/uniprotkb/G3X7Q6/entry", "sequence": { "sequence": "MAAPEAWRARSCWFCEVAAATTMEATSREAAPAKSSASGPSAPPALFELCGRAVSAHMGVLESGVWGKSRDEGLPLATNGGLSTQAIWRRLWDELMKTRPSSLESVTCWRAKFMEAFFSHVLRGTIDVSSDRRLCDQRFSPLLHSSRHVRQLTICNMLQGATELVAEPNRRVLETLASSLHTLKFRHLLFSDVAAQQSLRQLLHQLIHHGAVSQVSLYSWPVPESALFILILTMSAGFWQPGPGGPPCRLCGEASRGRAPSRDEGSLLLGSRRPRRDAAERCAAALMASRRKSEAKQTARAAPATRVTRRSTQESLTAGGTDSKREPLPPATSHEAPGTKRPPSAPATTSSASASSSTSSSKRAPASSAPQPKPLKRFKRGCGAESEDLYDFVFIVAGEKEDGEEMEIGEVACGALDGSDPSCLGLPALEASQRFRSISTLELFTVPLSTEAALTLCHLLSSWVSLESLTLSYNGLGSNIFRLLDSLRALSVQAGCRLRALHLSDLFSPLPILELTRAIVRALPLLRVLSIRVDHPSQRDNPAVPGNAGPPSNVIGDEEIPENCLEQLEMGFPRGAQPAPLLCSVLKASGSLQQLSLDSATFASPQDFGLVLQTLKEYNLTLKRLSFHDMNLADCQSEVLFLLQNLTLQEITFSFCRLFEKRPAQFLPEMVAAMKGNSTLKGLRLPGNRLGNAGLLALADVFSEDSSSSLCQLDISSNCIKPDGLLEFAKRLERWGRGAFGHLRLFQNWLDQDAVTAREAIRRLRATCHVVSDSWDSSQAFADYVSTM", "length": 788, "header": "tr|G3X7Q6-1|G3X7Q6_BOVIN Computationally mapped isoform of Leucine-rich repeat-containing protein 41 OS=Bos taurus OX=9913 GN=LRRC41 PE=4 SV=2 CANONICAL=G3N2Y1-1" }, "locus": { "chromosome": "3", "start_pos": 99817293, "end_pos": 99799454, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000043099.5", "url": "https://www.ensembl.org/id/ENSBTAT00000043099.5" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000040694.3", "url": "https://www.ensembl.org/id/ENSBTAP00000040694.3" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [ { "id": "R-BTA-8951664", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-BTA-8951664", "resource": "Reactome", "description": "Neddylation" }, { "id": "R-BTA-9706019", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-BTA-9706019", "resource": "Reactome", "description": "RHOBTB3 ATPase cycle" }, { "id": "R-BTA-983168", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-BTA-983168", "resource": "Reactome", "description": "Antigen processing: Ubiquitination & Proteasome degradation" } ], "orthologs": [ { "uniprot_canonical_ac": "A0A8V0ZYT7-1", "protein_name": "Leucine-rich repeat-containing protein 41", "gene_name": "LRRC41", "tax_id": 9031, "organism": "Gallus gallus", "sequence": { "sequence": "MQKVEELLRALLLCVGPRGHPRIAQLQALPGLHTLLRLLTVLPDRALPGHLLRGLLPLLSVFRLERAEAAARRAGLSTQPIWRKLWDDVMKTRPPNSENIPCWRKKFFETFFSNVLHGVLDVSSDWRLNDRHFSPLLHSSPHVSQLTLCNMLQGAVELAAEHNQKVLENLASSLRILKFQHLLSSDQSIRRSLVLLLHRLIHHGSVSHVSMCAWPVPDTVLLVLILSMSAGFWRSGNALTYHSSPCGLCREEGDTQSQKSTQERPEKGCCSEREWSDGEHQKESPRALEKADMQAEVNGCVAGTGQNTALSGLNCFPLEKQACEEASIKVSCDHTSRQGSSCFSEQLSHHSALRKSRRRTKSAVGKKRRCLRRSRGLCADLDDLYDFVFTVAREDNSVSIDQNTITEGENADNLTSSSTGSPCCGHVGCKRRGGSTGIFSLKAAHRFRSVSTLELFSIPLSDDTCRTLSNLLSSWVSLENLVLSYNGLGANIFCILSGLRALSQYSDCCLRVLRVSDVFSHMPCMELVHCILSVFPRLHTLSVSFDLKNQLEGNRPEGNPSCSDAEIPECCLEQLEIRFPREPLHTAFLLPVLKASKSLQQLSLDSATLPSSQELGLLLQALKECNPNLKKLSFHDVNLADHQKEVLLLLQDPMLQEITFSFCRLFESCTTEFLSEIINTVKRNSSLKSLKLPGNRLGNHRLVALADIFSEDSSSSLCQLDVSSNCIKPDGLLEFTKKLEGYIQQRGGKIQFTHLRLFQNWLDQDAETAQEALRRLRAVCSVVNDSWDSSQAFADYISVM", "length": 800 }, "evidence": [ { "id": "G3N2Y1", "url": "https://omabrowser.org/oma/group/G3N2Y1/", "database": "OMA" } ], "glygen_name": "Chicken", "common_name": "Chicken" }, { "uniprot_canonical_ac": "Q15345-2", "protein_name": "Leucine-rich repeat-containing protein 41", "gene_name": "LRRC41", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MAAPEAWRARSCWFCEVAAATTMEATSREAAPAKSSASGPNAPPALFELCGRAVSAHMGVLESGVWALPGPILQSILPLLNIYYLERIEETALKKGLSTQAIWRRLWDELMKTRPSSLESVTCWRAKFMEAFFSHVLRGTIDVSSDRRLCDQRFSPLLHSSRHVRQLTICNMLQGATELVAEPNRRVLETLASSLHTLKFRHLLFSDVAAQQSLRQLLHQLIHHGAVSQVSLYSWPVPESALFILILTMSAGFWQPGPGGPPCRLCGEASRGRAPSRDEGSLLLGSRRPRRDAAERCAAALMASRRKSEAKQMPRAAPATRVTRRSTQESLTAGGTDLKRELHPPATSHEAPGTKRSPSAPAATSSASSSTSSYKRAPASSAPQPKPLKRFKRAAGKKGARTRQGPGAESEDLYDFVFIVAGEKEDGEEMEIGEVACGALDGSDPSCLGLPALEASQRFRSISTLELFTVPLSTEAALTLCHLLSSWVSLESLTLSYNGLGSNIFRLLDSLRALSGQAGCRLRALHLSDLFSPLPILELTRAIVRALPLLRVLSIRVDHPSQRDNPGVPGNAGPPSHIIGDEEIPENCLEQLEMGFPRGAQPAPLLCSVLKASGSLQQLSLDSATFASPQDFGLVLQTLKEYNLALKRLSFHDMNLADCQSEVLFLLQNLTLQEITFSFCRLFEKRPAQFLPEMVAAMKGNSTLKGLRLPGNRLGNAGLLALADVFSEDSSSSLCQLDISSNCIKPDGLLEFAKRLERWGRGAFGHLRLFQNWLDQDAVTAREAIRRLRATCHVVSDSWDSSQAFADYVSTM", "length": 812 }, "evidence": [ { "id": "G3N2Y1", "url": "https://omabrowser.org/oma/group/G3N2Y1/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "Q5M9H1-1", "protein_name": "Leucine-rich repeat-containing protein 41", "gene_name": "Lrrc41", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MAAPEAWRARSCWFCEVAAATTMEATSREAAPAKSSASGPSAPPALFELCGRAVSAHMGVLESGVWALPGPILQSILPLLNIYYLERIEETALKKGLSTQAIWRRLWDELMKTRPSSLESVTCWRAKFMEAFFSHVLRGTIDVSSDKRLCDQRFSPLLHSSRHVRQLTICNMLQGATELVAEPNRRVLETLASSLHTLKFRHLLFSDVAAQQSLRQLLHQLIHHGAVSQVSLYSWPVPESALFILILTMSAGFWQPGPGSLPCRLCGEASRGRAPSRDEGSLLLGSRRPRRDAAERCAAALMATRRKSEVKQVPRALPTSRVTRRSTQESLTIGGTDSKRELYPPATSYEASGTKQPSSAPTAASSSTSSKRAPASSVSQPKPLKRFKRATGKKGPRTRQGSGAESEDLYDFVFIVAGEKEDGEEMEIGEVACGALDGSDPSCLGLPALEASQRFRSISTLELFTVPLSTEAALTLCHLLSSWVSLESLTLSYNGLGSNIFRLLDSLRVLSGQAGCRLRALHLSDLFSPLPILELTRAIVRALPLLRVLSIRVDHPSQRDNPAVPENAGPPGHIIGDEEIPENCLEQLEMGFPRGAQPAPLLCSVLKASGSLQQLSLDSATFASPQDFGLVLQTLKEYNLSLKRLSFHDMNLADCQSEVLFLLKNLTLQEITFSFCRLFEKRPAQFLPEMVAAMKGNSTLKGLRLPGNRLGNAGLLALADVFSEDSSSSLCQLDISSNCIKPDGLLEFAKRLERWGRGAFGHLRLFQNWLDQDAVTAREAIRRLRATCHVVSDSWDSTQAFADYVSTM", "length": 808 }, "evidence": [ { "id": "G3N2Y1", "url": "https://omabrowser.org/oma/group/G3N2Y1/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "Q8K1C9-1", "protein_name": "Leucine-rich repeat-containing protein 41", "gene_name": "Lrrc41", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MAAPEAWRARSCWFCEVAAATTMEATSREAAPAKSSASGPSAPPALFELCGRAVSAHMGVLESGVWALPGPILQSILPLLNIYYLERIEETALKKGLSTQAIWRRLWDELMKTRPSSLESVTCWRAKFMEAFFSHVLRGTIDVSSDKRLCDQRFSPLLHSSRHVRQLTICNMLQGATELVAEPNRRVLETLASSLHTLKFRHLLFSDVAAQQSLRQLLHQLIHHGAVSQVSLYSWPVPESALFILILTMSAGFWQPGPGSLPCRLCGEASRGRAPSRDEGSLLLGSRRPRRDAAERCAAALMATRRKSEVKQMPRAVPPTRVTRRSTQESLAIGGTDSKLYLPATSYEASGTKQPSAPAAASASSSTSSKRAPASSASQPKPLKRFKRAAGKKGPRTRQGSGAESEDLYDFVFIVAGEKEDGEEMEIGEVACGALDGSDPSCLGLPALEASQRFRSISTLELFTVPLSTEAALTLCHLLSSWVSLESLTLSYNGLGSNIFRLLDSLRALSGQAGCRLRALHLSDLFSPLPILELTRAIVRALPLLRVLSIRVDHPSQRDNPAVPENAGPPGHIVGDEEIPENCLEQLEMGFPRGAQPAPLLCSVLKASGSLQQLSLDSATFASPQDFGLVLQTLKEHNLSLKRLSFHDMNLADCQSEVLFLLKNLTLQEITFSFCRLFEKRPVQFLPEMVAAMKGNSTLKGLRLPGNRLGNAGLLALADVFSEDSSSSLCQLDISSNCIKPDGLLEFAKRLERWGRGAFGHLRLFQNWLDQDAVTAREAIRRLRATCHVVSDSWDSTQAFADYVSTM", "length": 807 }, "evidence": [ { "id": "G3N2Y1", "url": "https://omabrowser.org/oma/group/G3N2Y1/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" } ], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 2, "go_terms": [ { "name": "nucleus", "id": "GO:0005634", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005634", "evidence": [ { "database": "UniProtKB", "id": "G3N2Y1", "url": "https://www.uniprot.org/uniprotkb/G3N2Y1" } ], "pmid": "" }, { "name": "cytoplasm", "id": "GO:0005737", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005737", "evidence": [ { "database": "UniProtKB", "id": "G3N2Y1", "url": "https://www.uniprot.org/uniprotkb/G3N2Y1" } ], "pmid": "" } ] }, { "name": "Molecular Function", "total": 1, "go_terms": [ { "name": "identical protein binding", "id": "GO:0042802", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0042802", "evidence": [ { "database": "UniProtKB", "id": "G3N2Y1", "url": "https://www.uniprot.org/uniprotkb/G3N2Y1" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 644, "end_pos": 646, "annotation": "n_glycosylation_sequon" }, { "start_pos": 670, "end_pos": 672, "annotation": "n_glycosylation_sequon" }, { "start_pos": 702, "end_pos": 704, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [ { "pdb_id": "AF-G3N2Y1-F1", "pdb_chain": "global", "start_pos": 1, "end_pos": 813, "overlap": "1.0", "method": "AlphaFold", "type": "alphafold", "resolution": -1.0, "url": "https://data.glygen.org/ln2downloads/pdb/current/AF-G3N2Y1-F1.pdb", "url_external": "https://alphafold.ebi.ac.uk/entry/G3N2Y1" } ], "lectin_list": [], "domain_list": [], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" }, { "name": "homologset.oma", "label": "OMA Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 644, "end_pos": 646 }, { "start_pos": 670, "end_pos": 672 }, { "start_pos": 702, "end_pos": 704 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ], "tool_support": { "graph_view": "yes" } }, { "uniprot_canonical_ac": "G3N2Z0-1", "uniprot_ac": "G3N2Z0", "uniprot_id": "G3N2Z0_BOVIN", "mass": { "chemical_mass": 139499.0, "monoisotopic_mass": 139499.0 }, "refseq": {}, "gene_names": [ { "name": "PCARE", "type": "recommended", "evidence": [ { "id": "G3N2Z0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3N2Z0" } ] } ], "protein_names": [ { "name": "Photoreceptor cilium actin regulator", "type": "synonym", "evidence": [ { "id": "G3N2Z0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3N2Z0/entry#names_and_taxonomy" } ] } ], "function": [], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Bos taurus", "taxid": 9913, "evidence": [ { "database": "UniProtKB", "id": "G3N2Z0", "url": "https://www.uniprot.org/uniprotkb/G3N2Z0" } ], "common_name": "Bovine", "glygen_name": "Bovine", "reference_species": "Bos taurus [9913]" } ], "gene": [ { "name": "PCARE", "url": "https://www.uniprot.org/uniprotkb/G3N2Z0", "locus": { "chromosome": "11", "start_pos": 70769467, "end_pos": 70760932, "strand": "-", "evidence": [ { "database": "Ensembl Gene", "id": "ENSBTAG00000016934", "url": "https://www.ensembl.org/id/ENSBTAG00000016934" } ] } } ], "crossref": [ { "id": "ENSBTAG00000016934", "url": "https://bgee.org/?page=gene&gene_id=ENSBTAG00000016934", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "IPR029352", "url": "https://www.ebi.ac.uk/interpro/entry/IPR029352", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "G3N2Z0", "url": "https://www.orthodb.org/?gene=G3N2Z0", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR22017", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR22017", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR22017:SF0", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR22017:SF0", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF15449", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF15449", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "G3N2Z0", "url": "https://www.uniprot.org/uniprotkb/G3N2Z0", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "G3N2Z0-1", "url": "https://www.uniprot.org/uniprotkb/G3N2Z0-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MGCTPSHSDLVNSVAKSGIQFFKKPKAILPAHQRASERGSLPLLVQSSTCYDPGGGSSEEQPSPRWTQTVADSLCQPTRDPTAGKAKDMERLIPETKTSPSQLNKSQSCMATDIPFKRQSSHGSQGAAFSGEESEESITQETSKWAKRPKCHRSSKQGHYRQTILPAHESEDKVDFPDPLVKAHQRTYTYLHACLSKYEAVLSITHQATQTHELLQPMVSFLMLCFDEVNQLLGEISKDGDKLLQEVRKDLAWPLKKGEPQEQPDLLQQLLQYTVSKLQELSSTVALLTSSLLEGSGSYLNAAAAHLGNKLSTKRGADEHLLRALGHLESLASSHSDPEAWDLPLCSEDSGIGADNESVQLADKLGKQASWDLVPEAAEWRPAISPTVEARLSGHTWQQSPFRMGLDGPQDCPLSRPLTAKVHPAVQGGSGSPWSSVAGPENTASRPWGLGQSAPCGPPGMGTSGEAHLSKGSRCMDAPSFSEGEDSSSEEEEDEGSCTSPCTWRKNASHPRPRSSPASAESPFQPHPRRLRSPQAREMVLKMKEAISEKIKFVPVPSEHQDWMEEEERTTVPPRPSTASGSRRTPSRQRRSQSEGCLKSHTEDTTLQELQRVQRDLSQRLEAFYSLGTRWQGQSQEPVMQPRAATLRPDNRCWVVPSSAISKLKSSFTKNFSILPSQDKSILQKCCSRPEGEQPGQGKAEGLPSIIPPGERAHEAPAVRDQTIRSCPTRTSVKKLIETFSPTESLRTLGDSQDSGPSPCPKKWGVPSMPPRFPIYRGLAPLYPKPRISPAVGGESLRMGPGWRPLAPTFPPLLTAEATKSEDLNWETEENPEDLPPPPLEILMDQSFTSLEPPESNKPAESPLEGTHVPGLGGTGSARRTWASPRLRVSMSPTDLLPSKSTATLTRARSTEPGNSKGSCNTGKLALDFNHPPAASGNPEVQSSRAQSQVRADRASGLSKPPRKVIHWLHSSHTSGQNRISEPSLSRPRQTQGRSPVLVRKASPTRAHWTPRVDKRHSGLPSTHRSAQPSAPCVHGSPSPPLSPPVSPRGLSLPTVKKRASPPLQHKLHSPPSASPLAQHKISSPPPQRTEAGSLASGPSPSPPASPSQGPKETQDSEDSRAATASGNTRSIFCPATSSLFEAKLPFSTVHPLTPSSLPPEAGGPLETPTGGWRGSSGPRMRTDSQRGTTLCALNPQPFIRRTASDPRPGVRLHLPVPGATSSACESQHGQSSGSEESPKDTEPWKSPCGLELKGNSRGVPSPELCVLGHGLQREASVGHAQDKSQQKEVT", "length": 1291, "header": "tr|G3N2Z0-1|G3N2Z0_BOVIN Isoform 1 of Photoreceptor cilium actin regulator OS=Bos taurus OX=9913 GN=PCARE PE=4 SV=3 CANONICAL=G3N2Z0-1" }, "isoforms": [ { "isoform_ac": "G3N2Z0-1", "url": "https://www.uniprot.org/uniprotkb/G3N2Z0/entry", "sequence": { "sequence": "MGCTPSHSDLVNSVAKSGIQFFKKPKAILPAHQRASERGSLPLLVQSSTCYDPGGGSSEEQPSPRWTQTVADSLCQPTRDPTAGKAKDMERLIPETKTSPSQLNKSQSCMATDIPFKRQSSHGSQGAAFSGEESEESITQETSKWAKRPKCHRSSKQGHYRQTILPAHESEDKVDFPDPLVKAHQRTYTYLHACLSKYEAVLSITHQATQTHELLQPMVSFLMLCFDEVNQLLGEISKDGDKLLQEVRKDLAWPLKKGEPQEQPDLLQQLLQYTVSKLQELSSTVALLTSSLLEGSGSYLNAAAAHLGNKLSTKRGADEHLLRALGHLESLASSHSDPEAWDLPLCSEDSGIGADNESVQLADKLGKQASWDLVPEAAEWRPAISPTVEARLSGHTWQQSPFRMGLDGPQDCPLSRPLTAKVHPAVQGGSGSPWSSVAGPENTASRPWGLGQSAPCGPPGMGTSGEAHLSKGSRCMDAPSFSEGEDSSSEEEEDEGSCTSPCTWRKNASHPRPRSSPASAESPFQPHPRRLRSPQAREMVLKMKEAISEKIKFVPVPSEHQDWMEEEERTTVPPRPSTASGSRRTPSRQRRSQSEGCLKSHTEDTTLQELQRVQRDLSQRLEAFYSLGTRWQGQSQEPVMQPRAATLRPDNRCWVVPSSAISKLKSSFTKNFSILPSQDKSILQKCCSRPEGEQPGQGKAEGLPSIIPPGERAHEAPAVRDQTIRSCPTRTSVKKLIETFSPTESLRTLGDSQDSGPSPCPKKWGVPSMPPRFPIYRGLAPLYPKPRISPAVGGESLRMGPGWRPLAPTFPPLLTAEATKSEDLNWETEENPEDLPPPPLEILMDQSFTSLEPPESNKPAESPLEGTHVPGLGGTGSARRTWASPRLRVSMSPTDLLPSKSTATLTRARSTEPGNSKGSCNTGKLALDFNHPPAASGNPEVQSSRAQSQVRADRASGLSKPPRKVIHWLHSSHTSGQNRISEPSLSRPRQTQGRSPVLVRKASPTRAHWTPRVDKRHSGLPSTHRSAQPSAPCVHGSPSPPLSPPVSPRGLSLPTVKKRASPPLQHKLHSPPSASPLAQHKISSPPPQRTEAGSLASGPSPSPPASPSQGPKETQDSEDSRAATASGNTRSIFCPATSSLFEAKLPFSTVHPLTPSSLPPEAGGPLETPTGGWRGSSGPRMRTDSQRGTTLCALNPQPFIRRTASDPRPGVRLHLPVPGATSSACESQHGQSSGSEESPKDTEPWKSPCGLELKGNSRGVPSPELCVLGHGLQREASVGHAQDKSQQKEVT", "length": 1291, "header": "tr|G3N2Z0-1|G3N2Z0_BOVIN Isoform 1 of Photoreceptor cilium actin regulator OS=Bos taurus OX=9913 GN=PCARE PE=4 SV=3 CANONICAL=G3N2Z0-1" }, "locus": { "chromosome": "11", "start_pos": 70769464, "end_pos": 70760932, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000063365.3", "url": "https://www.ensembl.org/id/ENSBTAT00000063365.3" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000056261.3", "url": "https://www.ensembl.org/id/ENSBTAP00000056261.3" } ] } } ], "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "other", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 387, "start_aa": "Thr", "end_pos": 387, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr387", "evidence": [ { "id": "", "database": 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"url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF15843", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "XP_003585737", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_003585737", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "G3N2Z9", "url": "https://www.uniprot.org/uniprotkb/G3N2Z9", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "G3N2Z9-1", "url": "https://www.uniprot.org/uniprotkb/G3N2Z9-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MWGPGITAEGVSVAPAPPPLLPLLLLLALALVAPSRGGGGCAELACGERERCCDAANATAVRCCKLPLHAFLDNVGWFVRKLSGLLILLVLFAIGYFLQRIICPSPRRYPRGQARPGPPGGAGQPGAAGPPDDEDDDSPELLRDEVAAGSQDSLLDSGGGGGRGRAGGGRSAPSCASEHELRVVSPVFLQLPSYEEVKYLPTYEESMRLQQLSPGEVVLPVSVLGRPRGGGAGESDGGGEGRFPLI", "length": 246, "header": "tr|G3N2Z9-1|G3N2Z9_BOVIN Isoform 1 of Chromosome 1 C3orf80 homolog OS=Bos taurus OX=9913 GN=C1H3orf80 PE=4 SV=2 CANONICAL=G3N2Z9-1" }, "isoforms": [ { "isoform_ac": "G3N2Z9-1", "url": "https://www.uniprot.org/uniprotkb/G3N2Z9/entry", "sequence": { "sequence": "MWGPGITAEGVSVAPAPPPLLPLLLLLALALVAPSRGGGGCAELACGERERCCDAANATAVRCCKLPLHAFLDNVGWFVRKLSGLLILLVLFAIGYFLQRIICPSPRRYPRGQARPGPPGGAGQPGAAGPPDDEDDDSPELLRDEVAAGSQDSLLDSGGGGGRGRAGGGRSAPSCASEHELRVVSPVFLQLPSYEEVKYLPTYEESMRLQQLSPGEVVLPVSVLGRPRGGGAGESDGGGEGRFPLI", "length": 246, "header": "tr|G3N2Z9-1|G3N2Z9_BOVIN Isoform 1 of Chromosome 1 C3orf80 homolog OS=Bos taurus OX=9913 GN=C1H3orf80 PE=4 SV=2 CANONICAL=G3N2Z9-1" }, "locus": { "chromosome": "1", "start_pos": 107220619, "end_pos": 107219882, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000106519.1", "url": "https://www.ensembl.org/id/ENSBTAT00000106519.1" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000093518.1", "url": "https://www.ensembl.org/id/ENSBTAP00000093518.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [ { "id": "bta:100847848", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?bta:100847848", "resource": "KEGG Pathway" } ], "orthologs": [ { "uniprot_canonical_ac": "A0A287AX19-1", "protein_name": "Chromosome 13 C3orf80 homolog", "gene_name": "C13H3orf80", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MWGLGVTAEGLSVAPPPPPLLPLLLLLTLALVAPSRGGGGCAELACGERERCCDAANATAVRCCKLPLHAFLDNVGWFVRKLSGLLILLVLFAIGYFLQRIICPSPRRYPRGQARPGQGRPGPPGCAGQPGAPVPPDDDDDDSPALLRDEAAAGSQDSLLDSGGGGRGRAGGGRSATSCASEHELRVVSPVFLQLPSYEEVKYLPTYEESMRLQQLSPGDVVLPVSVLGRPRGGGAGESNDGGQGRFPLI", "length": 250 }, "evidence": [ { "id": "G3N2Z9", "url": "https://omabrowser.org/oma/group/G3N2Z9/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "A0ABK0LC12-1", "protein_name": "Similar to human chromosome 3 open reading frame 80", "gene_name": "C2h3orf80", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MWGPGVTTEGLSVAPAPPPLLPLLLLLALALVAPSRGGGGCAELACGERERCCDSANATAVRCCKLPLHAFLDNVGWFVRKLSGLLILLVLFAIGYFLQRIICPSPRRYPRGQARPGQARPGPPGGAGPPGTAGPPDDDDDSPALLRDEVAAGSQDSLLDSGGGRGRGGGGRLPPSSVSEHELRVVSPVFLQLPSYEEVKYLPTYEESMRLQQLNPAEVVLPVSVLGRPRGGSAGDPDGGQGRFPLI", "length": 247 }, "evidence": [ { "id": "G3N2Z9", "url": "https://omabrowser.org/oma/group/G3N2Z9/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "E9Q0B3-1", "protein_name": "Uncharacterized membrane protein C3orf80 homolog", "gene_name": "", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MWGPGVTAEGLSVAPAPPPLLPLLLLLALALVAPSRGGGGCAELACGERERCCDSANATAVRCCKLPLHAFLDNVGWFVRKLSGLLILLVLFAIGYFLQRIICPSPRRYPRGQARPGQARPGPPGGAGPPGTAGPPDDDDDSPALLRDEVAAGSQDSLLDSGGGRGRGSGGRLPPSCVSEHELHVVSPVFLQLPSYEEVKYLPTYEESMRLQQLSPAEVVLPVSVLGRPRGGSAGDSDGGQVRFPLI", "length": 247 }, "evidence": [ { "id": "G3N2Z9", "url": "https://omabrowser.org/oma/group/G3N2Z9/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "F5H4A9-1", "protein_name": "Uncharacterized membrane protein C3orf80", "gene_name": "C3orf80", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MWGPGVTAEGLSVAPAPPPLLPLLLLLALALVAPSRGGGGCAELACGERERCCDATNATAVRCCKLPLHAFLDNVGWFVRKLSGLLILLVLFAIGYFLQRIICPSPRRYPRGQARPGQRPGPPGGAGPLGGAGPPDDDDDSPALLRDEAAAGSQDSLLDSGGGGRGRGGGGRSDPSCASEHEMRVVSPVFLQLPSYEEVKYLPTYEESMRLQQLSPGEVVLPVSVLGRPRGGVAAEPDGGEGRYPLI", "length": 247 }, "evidence": [ { "id": "G3N2Z9", "url": "https://omabrowser.org/oma/group/G3N2Z9/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" } ], "go_annotation": {}, "pro_annotation": [], "site_annotation": [ { "start_pos": 57, "end_pos": 59, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "homologset.oma", "label": "OMA Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 57, "end_pos": 59 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": 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"total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ], "tool_support": { "graph_view": "yes" } }, { "uniprot_canonical_ac": "G3N308-1", "uniprot_ac": "G3N308", "uniprot_id": "G3N308_BOVIN", "mass": { "chemical_mass": 34167.0, "monoisotopic_mass": 34167.0 }, "refseq": { "ac": "XP_005227500", "name": "ankyrin repeat domain-containing protein SOWAHD", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_005227500" }, "gene_names": [ { "name": "SOWAHD", "type": "recommended", "evidence": [ { "id": "G3N308", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3N308" } ] }, { "name": "SOWAHD", "type": "synonym", "evidence": [ { "id": "XP_005227500", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_005227500" } ] } ], "protein_names": [ { "name": "Sosondowah ankyrin repeat domain family member D", "type": "synonym", "evidence": [ { "id": "G3N308", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3N308/entry#names_and_taxonomy" } ] }, { "name": "ankyrin repeat domain-containing protein SOWAHD", "type": "synonym", "evidence": [ { "id": "XP_005227500", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_005227500" } ] } ], "function": [], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Bos taurus", "taxid": 9913, "evidence": [ { "database": "UniProtKB", "id": "G3N308", "url": "https://www.uniprot.org/uniprotkb/G3N308" } ], "common_name": "Bovine", "glygen_name": "Bovine", "reference_species": "Bos taurus [9913]" } ], "gene": [ { "name": "SOWAHD", "url": "https://www.uniprot.org/uniprotkb/G3N308", "locus": { "chromosome": "X", "start_pos": 4123226, "end_pos": 4121119, "strand": "-", "evidence": [ { "database": "Ensembl Gene", "id": "ENSBTAG00000046012", "url": "https://www.ensembl.org/id/ENSBTAG00000046012" } ] } } ], "crossref": [ { "id": "G3N308", "url": "https://alphafold.ebi.ac.uk/entry/G3N308", "database": "AlphaFoldDB", "categories": [] }, { "id": "ENSBTAG00000046012", "url": "https://bgee.org/?page=gene&gene_id=ENSBTAG00000046012", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "523101", "url": "https://www.ncbi.nlm.nih.gov/gene/523101", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR002110", "url": "https://www.ebi.ac.uk/interpro/entry/IPR002110", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR036770", "url": "https://www.ebi.ac.uk/interpro/entry/IPR036770", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "bta:523101", "url": "https://www.genome.jp/dbget-bin/www_bget?bta:523101", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "HMFPFFQ", "url": "https://omabrowser.org/oma/group/HMFPFFQ/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "G3N308", "url": "https://www.orthodb.org/?gene=G3N308", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR14491", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR14491", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR14491:SF8", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR14491:SF8", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF12796", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF12796", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "XP_005227500", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_005227500", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "G3N308", "url": "https://www.uniprot.org/uniprotkb/G3N308", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "G3N308-1", "url": "https://www.uniprot.org/uniprotkb/G3N308-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MAEPRGAAKPAPKASFAQTKLSPRSAPQPRPSRVDAGNLSRYRGNATASREPPLLGGLMPSGTGSARRRGARLELLGLQGAAPAGWLSEERLEEQSPGGPNGPGGSRLCLEPREHAWILAAAEGRFEALQELLEAEPGLLLRGDPITGYSVLHWLAKHGRHEELILVHDFAQRQGLRLDVSAPGSGGLTPLHLAALQGHEMVIKVLVGALGADPTRRDHSGHRPCHYLRPDAPWSLRELSGAEDWERAGGRDGDPNNANNNSSNAAAWTVRRAPSAVGAQVVEKTARAAAAPAKAKDSVGNRVAQIQGLLRHMFPFFQDR", "length": 320, "header": "tr|G3N308-1|G3N308_BOVIN Isoform 1 of Sosondowah ankyrin repeat domain family member D OS=Bos taurus OX=9913 GN=SOWAHD PE=3 SV=1 CANONICAL=G3N308-1" }, "isoforms": [ { "isoform_ac": "G3N308-1", "url": "https://www.uniprot.org/uniprotkb/G3N308/entry", "sequence": { "sequence": "MAEPRGAAKPAPKASFAQTKLSPRSAPQPRPSRVDAGNLSRYRGNATASREPPLLGGLMPSGTGSARRRGARLELLGLQGAAPAGWLSEERLEEQSPGGPNGPGGSRLCLEPREHAWILAAAEGRFEALQELLEAEPGLLLRGDPITGYSVLHWLAKHGRHEELILVHDFAQRQGLRLDVSAPGSGGLTPLHLAALQGHEMVIKVLVGALGADPTRRDHSGHRPCHYLRPDAPWSLRELSGAEDWERAGGRDGDPNNANNNSSNAAAWTVRRAPSAVGAQVVEKTARAAAAPAKAKDSVGNRVAQIQGLLRHMFPFFQDR", "length": 320, "header": "tr|G3N308-1|G3N308_BOVIN Isoform 1 of Sosondowah ankyrin repeat domain family member D OS=Bos taurus OX=9913 GN=SOWAHD PE=3 SV=1 CANONICAL=G3N308-1" }, "locus": { "chromosome": "X", "start_pos": 4122642, "end_pos": 4121683, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000065997.3", "url": "https://www.ensembl.org/id/ENSBTAT00000065997.3" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000056279.1", "url": "https://www.ensembl.org/id/ENSBTAP00000056279.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [ { "id": "bta:523101", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?bta:523101", "resource": "KEGG Pathway" } ], "orthologs": [ { "uniprot_canonical_ac": "A6NJG2-1", "protein_name": "Ankyrin repeat domain-containing protein SOWAHD", "gene_name": "SOWAHD", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MAQLGGAANRAPTASLAPTSQSLRCAPQPRPSRADTGSLGRYWGKAAAAASREHPFPGTLMHSAAGSGRRRGALRELLGLQRAAPAGWLSEERAEELGGPSGPGSSRLCLEPREHAWILAAAEGRYEVLRELLEAEPELLLRGDPITGYSVLHWLAKHGRHEELILVHDFALRRGLRLDVSAPGSGGLTPLHLAALQGHDMVIKVLVGALGADATRRDHSGHRACHYLRPDAPWRLRELSGAEEWEMESGSGCTNLNNNSSGTTAWRAASAVGATAVETSRRVAASRTKAKDTAGSRVAQMHSLFRHLFPSFQDR", "length": 315 }, "evidence": [ { "id": "G3N308", "url": "https://omabrowser.org/oma/group/G3N308/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "F1RUA2-1", "protein_name": "Sosondowah ankyrin repeat domain family member D", "gene_name": "SOWAHD", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MAEPQGAAKRTPKASLAPTALNLRSAPQPRPSRADTGSLGRYRGNAAASREPPFHGSLMLSATGSGRRREGLRELLGLQGAAPAGWPSEERSEEPSPSGPNGPGGSGLCLEPREHAWILAAAEGRFEALQELLKAEPGLLLRGDPITGYTVLHWLAKHGRHEEIILVHDFAQRQGLQLDVSAPGSGGLTPLHLAALQGHDMVIKVLVGALGADPTRRDHSGHRACHYLRPEAPWSLRELSGAEDWETGGGGGGGSERNNANNNSSGGGAAWTLRRAPSAVGAPATETTARAAAAPAKKDSMGSRMAQVQGFLRHMFPFFQDR", "length": 322 }, "evidence": [ { "id": "G3N308", "url": "https://omabrowser.org/oma/group/G3N308/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" } ], "go_annotation": {}, "pro_annotation": [], "site_annotation": [ { "start_pos": 260, "end_pos": 262, "annotation": "n_glycosylation_sequon" }, { "start_pos": 261, "end_pos": 263, "annotation": "n_glycosylation_sequon" }, { "start_pos": 38, "end_pos": 40, "annotation": "n_glycosylation_sequon" }, { "start_pos": 45, "end_pos": 47, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [ { "pdb_id": "AF-G3N308-F1", "pdb_chain": "global", "start_pos": 1, "end_pos": 320, "overlap": "1.0", "method": "AlphaFold", "type": "alphafold", "resolution": -1.0, "url": "https://data.glygen.org/ln2downloads/pdb/current/AF-G3N308-F1.pdb", "url_external": "https://alphafold.ebi.ac.uk/entry/G3N308" } ], "lectin_list": [], "domain_list": [], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "homologset.oma", "label": "OMA Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 260, "end_pos": 262 }, { "start_pos": 261, "end_pos": 263 }, { "start_pos": 38, "end_pos": 40 }, { "start_pos": 45, "end_pos": 47 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ], "tool_support": { "graph_view": "yes" } }, { "uniprot_canonical_ac": "G3N314-1", "uniprot_ac": "G3N314", "uniprot_id": "G3N314_BOVIN", "mass": { "chemical_mass": 93905.0, "monoisotopic_mass": 93905.0 }, "refseq": { "ac": "XP_010818002", "name": "dynein axonemal assembly factor 5", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_010818002" }, "gene_names": [ { "name": "DNAAF5", "type": "recommended", "evidence": [ { "id": "G3N314", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3N314" } ] }, { "name": "DNAAF5", "type": "synonym", "evidence": [ { "id": "XP_010818002", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_010818002" } ] } ], "protein_names": [ { "name": "Dynein axonemal assembly factor 5", "type": "recommended", "evidence": [ { "id": "G3N314", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3N314/entry#names_and_taxonomy" } ] }, { "name": "HEAT repeat-containing protein 2", "type": "synonym", "evidence": [ { "id": "G3N314", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3N314/entry#names_and_taxonomy" } ] }, { "name": "dynein axonemal assembly factor 5", "type": "synonym", "evidence": [ { "id": "XP_010818002", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_010818002" } ] } ], "function": [ { "annotation": "Cytoplasmic protein involved in the delivery of the dynein machinery to the motile cilium. It is required for the assembly of the axonemal dynein inner and outer arms, two structures attached to the peripheral outer doublet A microtubule of the axoneme, that play a crucial role in cilium motility.", "evidence": [ { "database": "UniProtKB", "id": "G3N314", "url": "https://www.uniprot.org/uniprotkb/G3N314#function" }, { "database": "UniProtKB", "id": "ARBA00055740", "url": "https://www.uniprot.org/uniprotkb/ARBA00055740#function" }, { "database": "UniProtKB", "id": "A0AAA9TZ71", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TZ71#function" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Bos taurus", "taxid": 9913, "evidence": [ { "database": "UniProtKB", "id": "G3N314", "url": "https://www.uniprot.org/uniprotkb/G3N314" } ], "common_name": "Bovine", "glygen_name": "Bovine", "reference_species": "Bos taurus [9913]" } ], "gene": [ { "name": "DNAAF5", "url": "https://www.uniprot.org/uniprotkb/G3N314", "locus": { "chromosome": "25", "start_pos": 41884770, "end_pos": 41909075, "strand": "+", "evidence": [ { "database": "Ensembl Gene", "id": "ENSBTAG00000048140", "url": "https://www.ensembl.org/id/ENSBTAG00000048140" } ] } } ], "crossref": [ { "id": "G3N314", "url": "https://alphafold.ebi.ac.uk/entry/G3N314", "database": "AlphaFoldDB", "categories": [] }, { "id": "ENSBTAG00000048140", "url": "https://bgee.org/?page=gene&gene_id=ENSBTAG00000048140", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "100300875", "url": "https://www.ncbi.nlm.nih.gov/gene/100300875", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR011989", "url": "https://www.ebi.ac.uk/interpro/entry/IPR011989", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR016024", "url": "https://www.ebi.ac.uk/interpro/entry/IPR016024", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR021133", "url": "https://www.ebi.ac.uk/interpro/entry/IPR021133", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR052623", "url": "https://www.ebi.ac.uk/interpro/entry/IPR052623", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR056497", "url": "https://www.ebi.ac.uk/interpro/entry/IPR056497", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR057978", "url": "https://www.ebi.ac.uk/interpro/entry/IPR057978", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "bta:100300875", "url": "https://www.genome.jp/dbget-bin/www_bget?bta:100300875", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "AFQGPWA", "url": "https://omabrowser.org/oma/group/AFQGPWA/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "G3N314", "url": "https://www.orthodb.org/?gene=G3N314", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR16216", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR16216", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR16216:SF2", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR16216:SF2", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF24573", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF24573", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF25757", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF25757", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "XP_010818002", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_010818002", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0AAA9TZ71", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TZ71", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0AAA9TZ71-1", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TZ71-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "G3N314", "url": "https://www.uniprot.org/uniprotkb/G3N314", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "G3N314-1", "url": "https://www.uniprot.org/uniprotkb/G3N314-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MAALVAPEAAAPQGPTEAGETTEAAELSRSLSRLLPGLEADSKLGRRRALEALQRVLEAAQPEAPDADPDAAAAAFQGPWVHLLLPRLLRRLTDPAEGCRALAVHLLGLGLRRAARPRDALPRLLPALAARLASPEPARRPPPEACEELRLALVQLLGLAVRLTGAAFAPHLDDAVRALRCTLLDPFAAVRRESCECAAGLARATPDHFHMQSESLIGPLMQSISHQHWKVRVAVIEATGAAIQFGSGKSVDDVLPHFAQRLFDDVPQVRQAVMRVVGGWLLSLRDRYSFFHKLIPLLLSGFHDEIPEIASEASSLWERVGLQWQTENEEDLKDKLDFASPPPAHHPSPGSRPGLGCRELVFRNLSKILPAVCHDIDDWVAGTRVKSAQLLAVLLLHAEDHVTQHLEPVLRALLRACADEEAAVVSSCTRSAELVGTFVSPEVFLKLILSTLRKSPSPSGLLVLASLIQGCPREALRPHVKVIATELAQAHICQGSENRLYGERLLQCVQAVVSAGREDCRGAGEPLLEVLVTVLALWGPAGLSDKVQETLAALAAVEGMDGSQDLFRARVSPLLEWLAASHRDWTGHSVELLQLDVVLSHSGPALGEALPQLVPILRSCLQPARDPAMRLKLFSTLTGVLLGAPETVDSQGQLHGYLDTLVQDIFVPNLQWHAGRTAAAIRTAAVSCLWALVSSGGLSDGQIQDMQETLMPQILTTLEEDSQMTRLISCQIINLFLKTSNGVIDPDKFIKIYPELLKRLDDVSDDVRLAATSALVTWLQRVQSEASKCCYQSSVRHLYRELLVYLDDPEHAVQDAVLEALKAGSVLFPDLLVKETEAVLHKHRSPTYCEQLLQHLQALPPAQ", "length": 863, "header": "tr|G3N314-1|G3N314_BOVIN Isoform 1 of Dynein axonemal assembly factor 5 OS=Bos taurus OX=9913 GN=DNAAF5 PE=3 SV=2 CANONICAL=G3N314-1" }, "isoforms": [ { "isoform_ac": "A0AAA9TZ71-1", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TZ71/entry", "sequence": { "sequence": "MAALVAPEAAAPQGPTEAGETTEAAELSRSLSRLLPGLEADSKLGRRRALEALQRVLEAAQPEAPDADPDAAAAAFQGPWVHLLLPRLLRRLTDPAEGCRALAVHLLGLGLRRAARPRDALPRLLPALAARLASPEPARRPPPEACEELRLALVQLLGLAVRLTGAAFAPHLDDAVRALRCTLLDPFAAVRRESCECAAGLARATPDHFHMQSESLIGPLMQSISHQHWKVRVAVIEATGAAIQFGSGKSVDDVLPHFAQRLFDDVPQVRQAVMRVVGGWLLSLRDRYSFFHKLIPLLLSGFHDEIPEIASEASSLWERVGLQWQTENEEDLKDKLDFASPPPAHHPSPGSRPGLGCRELVFRNLSKILPAVCHDIDDWVAGTRVKSAQLLAVLLLHAEDHVTQHLEPVLRALLRACADEEAAVVSSRLYGERLLQCVQAVVSAGREDCRGAGEPLLEVLVTVLALWGPAGLSDKVQETLAALAAVEGMDGSQDLFRARVSPLLEWLAASHRDWTGHSVELLQLDVVLSHSGPALGEALPQLVPILRSCLQPARDPAMRLKLFSTLTGVLLGAPETVDSQGQLHGYLDTLVQDIFVPNLQWHAGRTAAAIRTAAVSCLWALVSSGGLSDGQIQDMQETLMPQILTTLEEDSQMTRLISCQIINLFLKTSNGVIDPDKFIKIYPELLKRLDDVSDDVRLAATSALVTWLQRVQSEASKCCYQSSVRHLYRELLVYLDDPEHAVQDAVLEALKAGSVLFPDLLVKETEAVLHKHRSPTYCEQLLQHLQALPPAQ", "length": 792, "header": "tr|A0AAA9TZ71-1|A0AAA9TZ71_BOVIN Computationally mapped isoform of Dynein axonemal assembly factor 5 OS=Bos taurus OX=9913 GN=DNAAF5 PE=3 SV=1 CANONICAL=G3N314-1" }, "locus": { "chromosome": "25", "start_pos": 41908876, "end_pos": 41885774, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000127075.1", "url": "https://www.ensembl.org/id/ENSBTAT00000127075.1" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000103619.1", "url": "https://www.ensembl.org/id/ENSBTAP00000103619.1" } ] } }, { "isoform_ac": "G3N314-1", "url": "https://www.uniprot.org/uniprotkb/G3N314/entry", "sequence": { "sequence": "MAALVAPEAAAPQGPTEAGETTEAAELSRSLSRLLPGLEADSKLGRRRALEALQRVLEAAQPEAPDADPDAAAAAFQGPWVHLLLPRLLRRLTDPAEGCRALAVHLLGLGLRRAARPRDALPRLLPALAARLASPEPARRPPPEACEELRLALVQLLGLAVRLTGAAFAPHLDDAVRALRCTLLDPFAAVRRESCECAAGLARATPDHFHMQSESLIGPLMQSISHQHWKVRVAVIEATGAAIQFGSGKSVDDVLPHFAQRLFDDVPQVRQAVMRVVGGWLLSLRDRYSFFHKLIPLLLSGFHDEIPEIASEASSLWERVGLQWQTENEEDLKDKLDFASPPPAHHPSPGSRPGLGCRELVFRNLSKILPAVCHDIDDWVAGTRVKSAQLLAVLLLHAEDHVTQHLEPVLRALLRACADEEAAVVSSCTRSAELVGTFVSPEVFLKLILSTLRKSPSPSGLLVLASLIQGCPREALRPHVKVIATELAQAHICQGSENRLYGERLLQCVQAVVSAGREDCRGAGEPLLEVLVTVLALWGPAGLSDKVQETLAALAAVEGMDGSQDLFRARVSPLLEWLAASHRDWTGHSVELLQLDVVLSHSGPALGEALPQLVPILRSCLQPARDPAMRLKLFSTLTGVLLGAPETVDSQGQLHGYLDTLVQDIFVPNLQWHAGRTAAAIRTAAVSCLWALVSSGGLSDGQIQDMQETLMPQILTTLEEDSQMTRLISCQIINLFLKTSNGVIDPDKFIKIYPELLKRLDDVSDDVRLAATSALVTWLQRVQSEASKCCYQSSVRHLYRELLVYLDDPEHAVQDAVLEALKAGSVLFPDLLVKETEAVLHKHRSPTYCEQLLQHLQALPPAQ", "length": 863, "header": "tr|G3N314-1|G3N314_BOVIN Isoform 1 of Dynein axonemal assembly factor 5 OS=Bos taurus OX=9913 GN=DNAAF5 PE=3 SV=2 CANONICAL=G3N314-1" }, "locus": { "chromosome": "25", "start_pos": 41908876, "end_pos": 41885774, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000063582.3", "url": "https://www.ensembl.org/id/ENSBTAT00000063582.3" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000056286.2", "url": "https://www.ensembl.org/id/ENSBTAP00000056286.2" } ] } } ], "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "other", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 16, "start_aa": "Thr", "end_pos": 16, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr16", "evidence": [ { "id": "", "database": "GlyGen", "url": "https://data.glygen.org/" } ], "filter_code": "000000000000000010000.00000000001000.0.01000" } ], "phosphorylation": [], "glycation": [], "keywords": [ "glycoprotein", "glycoprotein_predicted" ], "publication": [], "pathway": [ { "id": "bta:100300875", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?bta:100300875", "resource": "KEGG Pathway" } ], "orthologs": [ { "uniprot_canonical_ac": "A0A8V0ZGV1-1", "protein_name": "Dynein axonemal assembly factor 5", "gene_name": "DNAAF5", "tax_id": 9031, "organism": "Gallus gallus", "sequence": { "sequence": "MAACGAAELAQALSRPLSCLQGPECGRAARLRALEAIRAEVQERPLSSEAVQEVFEAQLVRPLARCLAGDAAERCRELALQLLLHGLSRCERPGEALPVLLPVLAQRLGPPQGAEPCEELRLGLLQLLGLLLRRGGTAVAPYLSDVVGILQAALLDHFAEVRRESCRCAVACAQAVPEHFHMQSESLIKPLMQTISHQHYRVRVDVIQATGTVIQFGNGKSVDDVLSHLAQRLFDEIPKVRQAVTTVIGEWLLHLRDRYSYFHKLIPLLLGSVTDDIPENMTLAWTYWEKVGLQWEKENEEDLKDKMDFSVPPSHYPKGVTRPGLGCRELVSRNLSKVLPGLCHDLTDWVESTRVKASQLLYVLLLHAEDHITQHMELLLRALYQACLDRESEVVRNCVKAAELIGTFVSPKVSLRLITSAFEITPKPSCLMVLAAVIRGSPKEILQPHLSDLGDTLSQAGVCQRSEEVLYMEQLLCCVRALIEVCQEDCQGICLQLMKVLVAVMAVPNSEHLKEKAEETMCSLAEVQQLDGFLYLYKQHILQLLEWVSVSHDSWTCYSPEILQLGVIATHSGPVIGEALHDFILILKTCLQPNKDPQMRLKLFTVLSELLQKANETINSQGLFPSYLEIVIKDILAPNLQWHAGRTAAAIRTTAVSCLWALIHCQMLAPEEILKVKDALMPQIIAAMDEDSKISRLMGCRIVGGILKVCGRQFDEIQLGKTYPEVLKRLDDASADVRLTAAHTLTDWFKCLKDSDVKSAMKSHIEFLYQELLIHLDDQDPDTQSAVLEVLKEGSVLYPELLVREVEVAIHKHRTPAYCNQLLHHIQTTREAA", "length": 833 }, "evidence": [ { "id": "G3N314", "url": "https://omabrowser.org/oma/group/G3N314/", "database": "OMA" } ], "glygen_name": "Chicken", "common_name": "Chicken" }, { "uniprot_canonical_ac": "A0ABK0LDA6-1", "protein_name": "Dynein axonemal assembly factor 5", "gene_name": "Dnaaf5", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MAAPAEAEVAAGFAEADEAAELTRALGRLLPGLETESKLGRRRALEALEHALEEAVRPGTDSAAFQGPWARLLLPRLLRLLTDPAEGCRALAAHLLDLGLRRAARPRDALPRLLPALTARLARPESTRPPPEPCEELRLALVQLLHLAVDLGGAALAPHLDDAVRALRGALLDPFAAVRREGCECAAALARAIPEHFHMQSESLIGPLMQTISHQHWKVRVAVIEATGTVIQFGNGNSVDDVLSHFAQRLFDDVPQVRQAVTSVVGGWLLNLRDRYSFFHKLTPLLLSSFSDEMPEVRQTATSLWEKVGLQWQEENEADLKDKLDFASPPPPNYPEHESRPGLGCRELVFRNLSKVLPAICHDITDWVVGTRLKAAQLLPVLLLHAEDHITQHLEIVLRTLHQACTDEEKAVVSSCVRAAELIGTFVSPEVFLKLILAMLKKAPSASGLLILASVIRGCPRNALQPHLKVIATELAQEHICQGSENNSYLEHLLLCVQTLLSVCQEDCCAASLQLSEVLVTIMAVSDAVSLEKKAQKTMDTLAEVEDIPSSQDLYRKHLGALLERLTASHGEWTVHSVQLLKFTVLLTQAGPAVGEALQHVIPTLRACLQPTTDPHMRLKLFSILSSLLLRPKDTVDSQGQFHGYLDMVINDILAPNLQWHAGRTAAAIRTATISCLWALISSDILSAKQVQEAQETLMPQVLATLEDDSQTTRLISCRIISRFLKNSGDTMEPEKFLKVYPELLKRLDDVSNDVRMAAASALLTWLKCIESVDGKSAYQSSVQFLYRELLVHLDDPESAIQDTVLEVLKEGSVLFPDVLVRETEAVVHKHRSATYCEQLLQHMQTMAAAR", "length": 851 }, "evidence": [ { "id": "G3N314", "url": "https://omabrowser.org/oma/group/G3N314/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "B9EJR8-1", "protein_name": "Dynein axonemal assembly factor 5", "gene_name": "Dnaaf5", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MAAPAEAEVAAAPGLTEAAEAAELTRALSRLLPGLETESKLGRRRALEALEQVLEEAVRPGADSAAFQGPWARLLLPRLLRLLSDPAEGCRALAAHLLDLGLRRAARPRDALPRLLPALSARLARPELARPPPEPCEELRLALVQLLHLAVDLGGAALAPHLDDAVRALRAALLDPFAAVRREGCECAAALARATPEHFHMQSESLIGPLMQTISHQHWKVRVAVIEATGTVIQFGSGNSVDDVLSHFAQRLFDDVPQVRQAVTSVVGGWLLNLRDRYSFLHKLTPLLLSSFSDEMPEIRQTATSLWEKVGLQWQQENEADLKDKLDFASPPPPNYPEHESRPGLGCRELVFRNLSKVLPAICHDITDWVVGTRVKAAQLLPVLLLHAEDHITQHLEIVLRTLHQACTDEEKAVVGSCIRAAELIGTFVSPEVFLKLILAMLKKAPSASGLLILASVIRGCPRNALQPHVTVIATELAQEHICQGSENNLYLEHLLLCVQALLSVCQEDCRAASLQFLEVLVTIMAVSDAVGLEKKAQKTMDTLAEVEDIPSSQDLYRKHVGALLERLTASHGEWAVHSVQLLKFTVLLTQAGPAVGEALQHVIPTLRACLQPSTDPHMRLKLFSILSMMLLRPKDTVDSQGQFRGYLDMVINDILAPNLQWHAGRTAAAIRTAAISCLWALISSDILSAKQVQEAQETLMPQVLATLEDDSQTTRLMSCRIINMFLKNSGDTMEPEKFLKVYPELLKRLDDVSNDVRMAAASALLTWLKCIESLDGKSAYQSSVQFLYRELLVHLDDPESAIQDTVLEVLKEGSVLFPDVLVRETEAVVHKHRSATYCEQLLQHMQTMAAAR", "length": 853 }, "evidence": [ { "id": "G3N314", "url": "https://omabrowser.org/oma/group/G3N314/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "F1RIY8-1", "protein_name": "Dynein axonemal assembly factor 5", "gene_name": "DNAAF5", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MAALVAAEAAVTRGPAEAAEAAEAAELSRVLSRLLPGLEADNKLGRRRALEALQRELEAARPEAPDADPAAAAAAFQGPWARLLLPRLLRCLTDPAEGCRALAVHLLDLGLRRAARPCDALPRLLPALAARLACPEPARRPPPEPCEELRLALVQLLGLAVRLGGTALAPHLDDAVRVLRSTLLDPFAAVRRESCECAAGLARATPDHFHMQSESLIGPLMQTVSHQHWKVRVAVIEATGAVIQFGSGKSVDDVLPHFAQRLFDDVPQVRRAVTRVVGGWLLDLRDRYSFFHKLIPLLLSGFDDDIPDIAHEATSLWEKVGLQWQTENEEDLKDKLDFASPPPAHHPSPERRPGLGCRELVFRNLAKILPAICHDITDWVAGTRVKSAQLLAVLLLHAEDHATQHLEPILRTLLHACADEEGAVVRSCISCAELIGAFVSPEVFLKLILTTLRKSPSAPGLLVLASVVRGCPREALRPHVKVIATELAQAHICQGPENPVYGERLLLCVQALVAGSREDCREAALPLLEVLVTVLALWGATGLGDKVQETLAALAAAEGVDGSQDLFREHLGPLLEWVAASHRDWTVHSAEVLLLDVVVTHSGPALGEALPQLVPILRSCLQPARDPALRLQLFSTLTRVLLRAQEAADARGQLRGCLDTVLKDILVPNLQWHAGRTAAAIRTAAVSCLWALVSSGVLSDKQVQEVQETLMPQVLTTLEEDSQTARLLSCRIVGVFLKASDGATEPDKFIKIYPELLKRLDDVSNEVRLAATSTLVTWLECIRNEAGQCCYRSSVQHLYRELLVYLDDPERAVQDAVLEALKAGSVLFPDVLVRETEAALHRHRSPAYCEQLLRHLQAAPPAQ", "length": 863 }, "evidence": [ { "id": "G3N314", "url": "https://omabrowser.org/oma/group/G3N314/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "Q86Y56-1", "protein_name": "Dynein axonemal assembly factor 5", "gene_name": "DNAAF5", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MAALGVAEAVAAPHPAEGAETAEAVELSRALSRLLPGLEADSKPGRRRALEALRRALEEPGPAADPTAFQGPWARLLLPRLLRCLSDPAEGCRALAVHLLDLGLRRAARPRDALPRLLPALAARLAGPVPARRPPEACEELRLALVQLLGLAVDLCGAALAPHLDDALRALRCSLLDPFAAVRRESCSCAAALAQATPDHFHMQSESLIGPLMQTISHQHWKVRVAAIEATGAVIHFGNGKSVDDVLSHFAQRLFDDVPQVRRAVASVVGGWLLCLRDRYSFFHKLIPLLLSSLNDEVPEVRQLAASLWEDVGLQWQKENEEDLKDKLDFAPPTPPHYPPHERRPVLGCRELVFRNLSKILPALCHDITDWVVGTRVKSAQLLPVLLLHAEDHATQHLEVVLRTLFQACTDEEAAVVQSCTRSAELVGTFVSPEVFLKLILSTLKKTPSASGLLVLASAMRGCPREALQPHLAAIATELAQAHICQASENDLYLERLLLCVQALVSVCHEDCGVASLQLLDVLLTIVALAGATGLRDKAQETMDSLAMVEGVSSCQDLYRKHIGPLLERVTASHLDWTAHSPELLQFSVIVAQSGPALGEALPHVVPTLRACLQPSQDPQMRLKLFSILSTVLLRATDTINSQGQFPSYLETVTKDILAPNLQWHAGRTAAAIRTAAVSCLWALTSSEVLSAEQIRDVQETLMPQVLTTLEEDSKMTRLISCRIINTFLKTSGGMTDPEKLIRIYPELLKRLDDVSNDVRMAAASTLVTWLQCVKGANAKSYYQSSVQYLYRELLVHLDDPERAIQDAILEVLKEGSGLFPDLLVRETEAVIHKHRSATYCEQLLQHVQAVPATQ", "length": 855 }, "evidence": [ { "id": "G3N314", "url": "https://omabrowser.org/oma/group/G3N314/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "Q8INF7-1", "protein_name": "Dynein axonemal assembly factor 5", "gene_name": "Dnaaf5", "tax_id": 7227, "organism": "Drosophila melanogaster", "sequence": { "sequence": "MGFDIDSQKICSDLESSDRRLKTTVLDELLDKCKEATNSESADKIADVFDKLYLHLLKCYEDRFESVRSKAIQVVSAFLSSLPPTDFHLMNVVSTLAERMGKAETVEPSEEIRLLYIAQLNLMICLYEKMENVGVFRECYPLVVKILIKSIKDDYPVVQREGCSAVVTLSRLADTQEFRPFTESILLPLYTMLNHKHAQARISAIQAIARLSLHMDASGDAMRRLFNEVSPLLMDTMPLVRREVGQMGILMLMELLDRYSFFERILPLVLCCLKDESPEVLNHIYPQWLKCGIQYFNENEAELSQQEISDLPVENYPKDVKRPTIGCRGLVQRSLRLLQLITRETSDWKDNVRLHALKLLYQFVLHAEAAMTAKFFEIYGDLAHACIDHVAEVNAEAAKVADLMGRLLSYDAWIDHGFDGLERNARESYMRCFYHMFTASLGGTYEQLMRLAKLLRCTDYSHTLKPGFQHYILKLLNTIVDKTLKINAGQNELEDLYESVYVCAIKVMALSSSLENVGDEDVNFGQTLIEKMVKLLNTSVPKIHERWFHLALQDVINLDAALEDNAEPVMLLNGLINMCHIRATYVHDLIEKVKIVFQHCCDSAQVKIFSSLSLATLFWSKTMNVERESSTQMLSEFVSQIVEPYLTWKAGSNAEAMRSLAMATLCALAQGAESESVEVLPSLAKYMPSLLEDRNVTTRHYAIKAVVYFREMSVEDLKPLAYATMQRMDDPSAGIRILAALAMGKLKPKFAETDTEENYEKEVWDAIVKRAMDLLLLYHESPEKDMRAAVAVTLKVLAKSHPEAWEERYQRALPMAQKKDLLTELYDKLTINEDSHTEVTSASQD", "length": 845 }, "evidence": [ { "id": "G3N314", "url": "https://omabrowser.org/oma/group/G3N314/", "database": "OMA" } ], "glygen_name": "Fruit fly", "common_name": "Fruit fly" } ], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 2, "go_terms": [ { "name": "cytoplasm", "id": "GO:0005737", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005737", "evidence": [ { "database": "UniProtKB", "id": "G3N314", "url": "https://www.uniprot.org/uniprotkb/G3N314" } ], "pmid": "" }, { "name": "cytosol", "id": "GO:0005829", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005829", "evidence": [ { "database": "UniProtKB", "id": "G3N314", "url": "https://www.uniprot.org/uniprotkb/G3N314" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 4, "go_terms": [ { "name": "cilium movement", "id": "GO:0003341", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003341", "evidence": [ { "database": "UniProtKB", "id": "G3N314", "url": "https://www.uniprot.org/uniprotkb/G3N314" } ], "pmid": "" }, { "name": "outer dynein arm assembly", "id": "GO:0036158", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0036158", "evidence": [ { "database": "UniProtKB", "id": "G3N314", "url": "https://www.uniprot.org/uniprotkb/G3N314" } ], "pmid": "" }, { "name": "inner dynein arm assembly", "id": "GO:0036159", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0036159", "evidence": [ { "database": "UniProtKB", "id": "G3N314", "url": "https://www.uniprot.org/uniprotkb/G3N314" } ], "pmid": "" }, { "name": "cell projection organization", "id": "GO:0030030", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030030", "evidence": [ { "database": "UniProtKB", "id": "G3N314", "url": "https://www.uniprot.org/uniprotkb/G3N314" } ], "pmid": "" } ] }, { "name": "Molecular Function", "total": 1, "go_terms": [ { "name": "dynein intermediate chain binding", "id": "GO:0045505", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0045505", "evidence": [ { "database": "UniProtKB", "id": "G3N314", "url": "https://www.uniprot.org/uniprotkb/G3N314" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 364, "end_pos": 366, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [ { "pdb_id": "AF-G3N314-F1", "pdb_chain": "global", "start_pos": 1, "end_pos": 863, "overlap": "1.0", "method": "AlphaFold", "type": "alphafold", "resolution": -1.0, "url": "https://data.glygen.org/ln2downloads/pdb/current/AF-G3N314-F1.pdb", "url_external": "https://alphafold.ebi.ac.uk/entry/G3N314" } ], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "G3N314", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3N314" }, { "id": "PF24573", "database": "Pfam", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF24573" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "Dynein axonemal assembly factor 5 HEAT-repeat", "eco_id": "ECO_0000259", "start_pos": 345, "end_pos": 537, "start_aa": "His", "end_aa": "Leu", "glycosite_overlap": [] }, { "evidence": [ { "id": "G3N314", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3N314" }, { "id": "PF25757", "database": "Pfam", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF25757" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "Dynein axonemal assembly factor 5 TPR repeats", "eco_id": "ECO_0000259", "start_pos": 38, "end_pos": 335, "start_aa": "Leu", "end_aa": "Lys", "glycosite_overlap": [] } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" }, { "name": "homologset.oma", "label": "OMA Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [ 16 ], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 364, "end_pos": 366 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 1 }, { "field": "total_sites", "count": 1 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 1 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "exact_sites", "count": 1 }, { "field": "exact_o_linked_sites", "count": 1 }, { "field": "fuzzy_sites", "count": 0 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_pos", "start_aa", "end_pos", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 1 }, { "field": "total_sites", "count": 1 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 1 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "exact_sites", "count": 1 }, { "field": "exact_o_linked_sites", "count": 1 }, { "field": "fuzzy_sites", "count": 0 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_pos", "start_aa", "end_pos", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ], "tool_support": { "graph_view": "yes" } }, { "uniprot_canonical_ac": "G3N331-1", "uniprot_ac": "G3N331", "uniprot_id": "G3N331_BOVIN", "mass": { "chemical_mass": 44464.0, "monoisotopic_mass": 44464.0 }, "refseq": { "ac": "XP_002686558", "name": "Krueppel-like factor 17 isoform X1", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_002686558" }, "gene_names": [ { "name": "KLF17", "type": "recommended", "evidence": [ { "id": "G3N331", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3N331" } ] }, { "name": "KLF17", "type": "synonym", "evidence": [ { "id": "XP_002686558", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_002686558" } ] } ], "protein_names": [ { "name": "Krueppel-like factor 17", "type": "recommended", "evidence": [ { "id": "G3N331", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3N331/entry#names_and_taxonomy" } ] }, { "name": "Krueppel-like factor 17 isoform X1", "type": "synonym", "evidence": [ { "id": "XP_002686558", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_002686558" } ] } ], "function": [ { "annotation": "Transcription repressor that binds to the promoter of target genes and prevents their expression. Acts as a negative regulator of epithelial-mesenchymal transition and metastasis in breast cancer. Specifically binds the 5'-CACCC-3' sequence in the promoter of ID1, a key metastasis regulator in breast cancer, and repress its expression. May be a germ cell-specific transcription factor that plays important roles in spermatid differentiation and oocyte development.", "evidence": [ { "database": "UniProtKB", "id": "G3N331", "url": "https://www.uniprot.org/uniprotkb/G3N331#function" }, { "database": "UniProtKB", "id": "ARBA00059130", "url": "https://www.uniprot.org/uniprotkb/ARBA00059130#function" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Bos taurus", "taxid": 9913, "evidence": [ { "database": "UniProtKB", "id": "G3N331", "url": "https://www.uniprot.org/uniprotkb/G3N331" } ], "common_name": "Bovine", "glygen_name": "Bovine", "reference_species": "Bos taurus [9913]" } ], "gene": [ { "name": "KLF17", "url": "https://www.uniprot.org/uniprotkb/G3N331", "locus": { "chromosome": "3", "start_pos": 101936165, "end_pos": 101951244, "strand": "+", "evidence": [ { "database": "Ensembl Gene", "id": "ENSBTAG00000047871", "url": "https://www.ensembl.org/id/ENSBTAG00000047871" } ] } } ], "crossref": [ { "id": "G3N331", "url": "https://alphafold.ebi.ac.uk/entry/G3N331", "database": "AlphaFoldDB", "categories": [] }, { "id": "ENSBTAG00000047871", "url": "https://bgee.org/?page=gene&gene_id=ENSBTAG00000047871", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "cd21574", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd21574", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "516413", "url": "https://www.ncbi.nlm.nih.gov/gene/516413", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR013087", "url": "https://www.ebi.ac.uk/interpro/entry/IPR013087", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR036236", "url": "https://www.ebi.ac.uk/interpro/entry/IPR036236", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "bta:516413", "url": "https://www.genome.jp/dbget-bin/www_bget?bta:516413", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "G3N331", "url": "https://www.orthodb.org/?gene=G3N331", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR23235", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR23235", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR23235:SF159", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR23235:SF159", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00096", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00096", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "XP_002686558", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_002686558", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "G3N331", "url": "https://www.uniprot.org/uniprotkb/G3N331", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "G3N331-1", "url": "https://www.uniprot.org/uniprotkb/G3N331-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MCNPSQVQMEQGAEGLNQWHVASHQFTEDAEKSMSILNMSSSPGSSGMHTSWNHSPLDIQHIPQCTELQRIPLASAEAPRQNASEMGPQFSMALPDHRVSYCPQLTFTPSQMTFTQGMSPSQPGMMIFKEPQMMPLGEPNIPGMAMTFGGNLRMPLNGPPASPPSGIPMMSHIRMRTMSYPGLPTVASNRDPLPPKTLLNPTVPSTEAQAMLPSVAQMLPPRQPHNFGMPPGGPPLLLALESQGSFVNQPVSQEDPFLPKQPIPAPQRAEQQYSRTQEKAPKRRSPVLRPYRCNYENCEKAYTKRSHLVSHQRKHTGERPYKCTWAACTWSFFRSDELGRHTRIHTKHRPHKCDQCGRQFMRSDHLRQHQRTHMRTPRSPDPPADNGCMAGPPPTPGL", "length": 398, "header": "tr|G3N331-1|G3N331_BOVIN Isoform 1 of Krueppel-like factor 17 OS=Bos taurus OX=9913 GN=KLF17 PE=3 SV=3 CANONICAL=G3N331-1" }, "isoforms": [ { "isoform_ac": "G3N331-1", "url": "https://www.uniprot.org/uniprotkb/G3N331/entry", "sequence": { "sequence": "MCNPSQVQMEQGAEGLNQWHVASHQFTEDAEKSMSILNMSSSPGSSGMHTSWNHSPLDIQHIPQCTELQRIPLASAEAPRQNASEMGPQFSMALPDHRVSYCPQLTFTPSQMTFTQGMSPSQPGMMIFKEPQMMPLGEPNIPGMAMTFGGNLRMPLNGPPASPPSGIPMMSHIRMRTMSYPGLPTVASNRDPLPPKTLLNPTVPSTEAQAMLPSVAQMLPPRQPHNFGMPPGGPPLLLALESQGSFVNQPVSQEDPFLPKQPIPAPQRAEQQYSRTQEKAPKRRSPVLRPYRCNYENCEKAYTKRSHLVSHQRKHTGERPYKCTWAACTWSFFRSDELGRHTRIHTKHRPHKCDQCGRQFMRSDHLRQHQRTHMRTPRSPDPPADNGCMAGPPPTPGL", "length": 398, "header": "tr|G3N331-1|G3N331_BOVIN Isoform 1 of Krueppel-like factor 17 OS=Bos taurus OX=9913 GN=KLF17 PE=3 SV=3 CANONICAL=G3N331-1" }, "locus": { "chromosome": "3", "start_pos": 101951111, "end_pos": 101936567, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000063796.3", "url": "https://www.ensembl.org/id/ENSBTAT00000063796.3" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000056304.3", "url": "https://www.ensembl.org/id/ENSBTAP00000056304.3" } ] } } ], "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "other", 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{ "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ], "tool_support": { "graph_view": "yes" } }, { "uniprot_canonical_ac": "G3N3B6-1", "uniprot_ac": "G3N3B6", "uniprot_id": "G3N3B6_BOVIN", "mass": { "chemical_mass": 53674.0, "monoisotopic_mass": 53674.0 }, "refseq": {}, "gene_names": [ { "name": "CCDC188", "type": "recommended", "evidence": [ { "id": "G3N3B6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3N3B6" } ] } ], "protein_names": [ { "name": "Coiled-coil domain containing 188", "type": "synonym", "evidence": [ { "id": "G3N3B6", "database": "UniProtKB", "url": 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"MGRGGRGPVGPAPATAPAHYDLPGPAQAFVTVVPEVPMSHDTQSSLSKRVVGQARPKPGPGVRKGSQGGMEGPKTLGPCGHTHPQCPQPPAPGSRGGCLDPPCPGFARWPCMAPLSPTHSMETARPFSALGTGGGGPRVGGEVPGNFITSEDGELQRQRPRDPARMRQGQMDTRLGWGWALHSSHEQEQRASRQVAGPSSGPRPCPCPPLIPGTGASASPRADPPQLQGIPLGPAEPSFLQLEQENQSLKRQNQDLREQLGALLGPGQQFLPLCPEHSSCTALAWSMTTDAADGLGAEPGAPPQPPEQACAQPLEDRAPLQLLRQELCRGEESFVQQSQNELQQIRLSFERKKMAITEVPPAGVWDGVAEVHMALNNQATGLLNLKKDIRGVLDQMEDIQLEILGERAQCRTQARKDQKMACRGKARLQLGCSEGLRGQLWLLALRLLLGALLACTAAYVYVVDPAPFEGMVPPLLSRAAVWKLRALLGPFLRLEVDGFLPF", "length": 502, "header": "tr|G3N3B6-1|G3N3B6_BOVIN Isoform 1 of Coiled-coil domain containing 188 OS=Bos taurus OX=9913 GN=CCDC188 PE=4 SV=3 CANONICAL=G3N3B6-1" }, "isoforms": [ { "isoform_ac": "G3N3B6-1", "url": "https://www.uniprot.org/uniprotkb/G3N3B6/entry", "sequence": { "sequence": "MGRGGRGPVGPAPATAPAHYDLPGPAQAFVTVVPEVPMSHDTQSSLSKRVVGQARPKPGPGVRKGSQGGMEGPKTLGPCGHTHPQCPQPPAPGSRGGCLDPPCPGFARWPCMAPLSPTHSMETARPFSALGTGGGGPRVGGEVPGNFITSEDGELQRQRPRDPARMRQGQMDTRLGWGWALHSSHEQEQRASRQVAGPSSGPRPCPCPPLIPGTGASASPRADPPQLQGIPLGPAEPSFLQLEQENQSLKRQNQDLREQLGALLGPGQQFLPLCPEHSSCTALAWSMTTDAADGLGAEPGAPPQPPEQACAQPLEDRAPLQLLRQELCRGEESFVQQSQNELQQIRLSFERKKMAITEVPPAGVWDGVAEVHMALNNQATGLLNLKKDIRGVLDQMEDIQLEILGERAQCRTQARKDQKMACRGKARLQLGCSEGLRGQLWLLALRLLLGALLACTAAYVYVVDPAPFEGMVPPLLSRAAVWKLRALLGPFLRLEVDGFLPF", "length": 502, "header": "tr|G3N3B6-1|G3N3B6_BOVIN Isoform 1 of Coiled-coil domain containing 188 OS=Bos taurus OX=9913 GN=CCDC188 PE=4 SV=3 CANONICAL=G3N3B6-1" }, "locus": { "chromosome": "17", "start_pos": 73019566, "end_pos": 73016566, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000064278.3", "url": "https://www.ensembl.org/id/ENSBTAT00000064278.3" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000056418.3", "url": 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"glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": 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"database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3N3B8" } ] }, { "name": "LOC100848138", "type": "synonym", "evidence": [ { "id": "XP_003586351", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_003586351" } ] } ], "protein_names": [ { "name": "Cadherin domain-containing protein", "type": "recommended", "evidence": [ { "id": "G3N3B8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3N3B8/entry#names_and_taxonomy" } ] }, { "name": "protocadherin beta-16", "type": "synonym", "evidence": [ { "id": "XP_003586351", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_003586351" } ] } ], "function": [], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Bos taurus", "taxid": 9913, "evidence": [ { "database": "UniProtKB", "id": "G3N3B8", "url": "https://www.uniprot.org/uniprotkb/G3N3B8" } ], "common_name": "Bovine", "glygen_name": "Bovine", "reference_species": "Bos taurus [9913]" } ], "gene": [ { "name": "LOC100848138", "url": "https://www.uniprot.org/uniprotkb/G3N3B8", "locus": {} } ], "crossref": [ { "id": "G3N3B8", "url": "https://alphafold.ebi.ac.uk/entry/G3N3B8", "database": "AlphaFoldDB", "categories": [] }, { "id": "ENSBTAG00000049493", "url": "https://bgee.org/?page=gene&gene_id=ENSBTAG00000049493", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "cd11304", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd11304", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "100848138", "url": "https://www.ncbi.nlm.nih.gov/gene/100848138", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR002126", "url": "https://www.ebi.ac.uk/interpro/entry/IPR002126", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR013164", "url": "https://www.ebi.ac.uk/interpro/entry/IPR013164", "database": "InterPro", "categories": [ 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"sequence": { "sequence": "METGRMHNHRQRQVLVFFVCLSMSWGSADLGPYSVVEETERGSFVANLAKDLELGLAEMATRAVRIISQGNKEHLQLKVQTGDLLLNEKLDREELCGPTEPCILHFQVLMEKPLEIFQAELRVKDINDHSPVFNEREIILKIPENSPTGTAFPLSNALDLDVGSNNIQNYTISPNFHFRVITHKRSDGRKYPELVLDKELDREEEPEISLTLTALDGGSPPRYGTAQVRIEVVDINDNAPQFQQLLYKVHIPENSPVGSLVVTVSASDVDSGLYGKISYTFFQPSEDISKTLEVNPKTGEIRLRKQVDFETVFSYEVDVKATDGGGLSGKCTLLLQVVDVNDNPPEVTVSALTSPIPENSPEIVVAVFSVSDPDSGDNGKTTCSIQDDLPFLLKPSVKNFYTLVTERTLDREERAEYNITITVTDMGTPRLKTEHNITVLVSDVNDNAPAFTQTSYTLWVRENNSPALHIGSVSATDTDAGANAQVTYSLLPPPDPLVPLASLVSINPDNGHLFALTSLDYEALRAFEFRVGATDRGSPALSSQALVRVLVADANDNAPFVLYPLQNASAPCTELVPRAAEPGYLVTKVVAVDGDAGQNAWLSYQLLKATEPGLFGVWAHNGEVRTARLLSERDAPKQRLVVLVKDNGEPPLSASVTLHVLLVDGFSQPYLPAPEAEAAAAAPADPLTVYLVVALASVSSLFLFSVLVFVAVRLCRRGGEASAGRCPVAEGHFPGHLVDVSGTGTLSQSYQYELCLTRETGTNEFKVLKPILPNLSSKSIGREVEENPSFQGSVGI", "length": 796, "header": "tr|G3N3B8-1|G3N3B8_BOVIN Isoform 1 of Cadherin domain-containing protein OS=Bos taurus OX=9913 GN=LOC100848138 PE=4 SV=4 CANONICAL=G3N3B8-1" }, 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Binds to pathogen-associated molecular patterns (PAMPs) present on the cell walls of Gram-positive and Gram-negative bacteria and fungi, behaving as a pattern recognition receptor (PRR). Induces bacterial and fungal aggregation and subsequent inhibition of PAMP-induced cytokine release. Does not possess intrinsic bactericidal activity. May play a role in the innate defense and homeostasis of certain epithelial surfaces.", "evidence": [ { "database": "UniProtKB", "id": "G3N3C5", "url": "https://www.uniprot.org/uniprotkb/G3N3C5#function" }, { "database": "UniProtKB", "id": "ARBA00058074", "url": "https://www.uniprot.org/uniprotkb/ARBA00058074#function" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Bos taurus", "taxid": 9913, "evidence": [ { "database": "UniProtKB", "id": "G3N3C5", "url": "https://www.uniprot.org/uniprotkb/G3N3C5" } ], "common_name": "Bovine", "glygen_name": "Bovine", "reference_species": "Bos taurus [9913]" } ], "gene": [ { "name": "", "url": "https://www.uniprot.org/uniprotkb/G3N3C5", "locus": {} } ], "crossref": [ { "id": "G3N3C5", "url": "https://alphafold.ebi.ac.uk/entry/G3N3C5", "database": "AlphaFoldDB", "categories": [] }, { "id": "ENSBTAG00000039755", "url": "https://bgee.org/?page=gene&gene_id=ENSBTAG00000039755", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "IPR001190", "url": "https://www.ebi.ac.uk/interpro/entry/IPR001190", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR036772", "url": "https://www.ebi.ac.uk/interpro/entry/IPR036772", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "PTHR19331", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR19331", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR19331:SF470", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR19331:SF470", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00530", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00530", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "G3N3C5", "url": "https://www.uniprot.org/uniprotkb/G3N3C5", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "G3N3C5-1", "url": "https://www.uniprot.org/uniprotkb/G3N3C5-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MNRNHVILVHVILWFSFTQITLVPIYRLVPFILYSSIGKSHELTLTFSPAGDWPTLRLVNGPGRCSGRVEVSYQGSWGSVCGKGWGLKEAHVVCRQLGCGWAVSTPPGAHFSPGFGKILLDNVHCSGEESHLALCAHDTWFTHSCGHEADAGAICERLLSVPAWRAAPVASLLIPTHTHIPHCAGRVEVFYQGAWGTVCDSLWDLPEANVVCRQLGCGRAMEAPGKAHFGEGSGKVLLDNMQSCAQEAMLTRSLSVGDWPELRLVGGSGRCSGRVEVLHEEAWGTVCDDLWDLNEAEVVCRQLGCGQAVSALGKAHFGPGSGDIFLDNLQCAGAERHLGQCAHSGWSEHNCGHHEDAGVICSGSLSSSCQSPPKCLRTTLLEFRVSQG", "length": 388, "header": "tr|G3N3C5-1|G3N3C5_BOVIN Isoform 1 of Soluble scavenger receptor cysteine-rich domain-containing protein SSC5D OS=Bos taurus OX=9913 GN= PE=4 SV=4 CANONICAL=G3N3C5-1" }, "isoforms": [ { "isoform_ac": "G3N3C5-1", "url": "https://www.uniprot.org/uniprotkb/G3N3C5/entry", "sequence": { "sequence": "MNRNHVILVHVILWFSFTQITLVPIYRLVPFILYSSIGKSHELTLTFSPAGDWPTLRLVNGPGRCSGRVEVSYQGSWGSVCGKGWGLKEAHVVCRQLGCGWAVSTPPGAHFSPGFGKILLDNVHCSGEESHLALCAHDTWFTHSCGHEADAGAICERLLSVPAWRAAPVASLLIPTHTHIPHCAGRVEVFYQGAWGTVCDSLWDLPEANVVCRQLGCGRAMEAPGKAHFGEGSGKVLLDNMQSCAQEAMLTRSLSVGDWPELRLVGGSGRCSGRVEVLHEEAWGTVCDDLWDLNEAEVVCRQLGCGQAVSALGKAHFGPGSGDIFLDNLQCAGAERHLGQCAHSGWSEHNCGHHEDAGVICSGSLSSSCQSPPKCLRTTLLEFRVSQG", "length": 388, "header": "tr|G3N3C5-1|G3N3C5_BOVIN Isoform 1 of Soluble scavenger receptor cysteine-rich domain-containing protein SSC5D OS=Bos taurus OX=9913 GN= PE=4 SV=4 CANONICAL=G3N3C5-1" }, "locus": { "chromosome": "26", "start_pos": 42629324, "end_pos": 42607080, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000066099.4", "url": "https://www.ensembl.org/id/ENSBTAT00000066099.4" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000056427.4", "url": "https://www.ensembl.org/id/ENSBTAP00000056427.4" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [], "orthologs": [], "go_annotation": { "categories": [ { "name": "Molecular Function", "total": 1, "go_terms": [ { "name": "scavenger receptor activity", "id": "GO:0005044", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005044", "evidence": [ { "database": "UniProtKB", "id": "G3N3C5", "url": "https://www.uniprot.org/uniprotkb/G3N3C5" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 1, "go_terms": [ { "name": "plasma membrane", "id": "GO:0005886", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005886", "evidence": [ { "database": "UniProtKB", "id": "G3N3C5", "url": "https://www.uniprot.org/uniprotkb/G3N3C5" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [ { "pdb_id": "AF-G3N3C5-F1", "pdb_chain": "global", "start_pos": 1, "end_pos": 388, "overlap": "1.0", "method": "AlphaFold", "type": "alphafold", "resolution": -1.0, "url": "https://data.glygen.org/ln2downloads/pdb/current/AF-G3N3C5-F1.pdb", "url_external": "https://alphafold.ebi.ac.uk/entry/G3N3C5" } ], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "G3N3C5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3N3C5" }, { "id": "PS50287", "database": "PROSITE", "url": "https://prosite.expasy.org/PS50287" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "SRCR", "eco_id": "ECO_0000259", "start_pos": 56, "end_pos": 156, "start_aa": "Leu", "end_aa": "Glu", "glycosite_overlap": [] } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ], "tool_support": { "graph_view": "yes" } }, { "uniprot_canonical_ac": "G3N3D3-1", "uniprot_ac": "G3N3D3", "uniprot_id": "G3N3D3_BOVIN", "mass": { "chemical_mass": 27678.0, "monoisotopic_mass": 27678.0 }, "refseq": {}, "gene_names": [ { "name": "KPLCE", "type": "recommended", "evidence": [ { "id": "G3N3D3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3N3D3" } ] }, { "name": "C3H1orf68", "type": "synonym", "evidence": [ { "id": "G3N3D3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3N3D3" } ] } ], "protein_names": [ { "name": "KPRP N-terminal and LCE C-terminal like protein", "type": "synonym", "evidence": [ { "id": "G3N3D3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3N3D3/entry#names_and_taxonomy" } ] } ], "function": [], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Bos taurus", "taxid": 9913, "evidence": [ { "database": "UniProtKB", "id": "G3N3D3", "url": "https://www.uniprot.org/uniprotkb/G3N3D3" } ], "common_name": "Bovine", "glygen_name": "Bovine", "reference_species": "Bos taurus [9913]" } ], "gene": [ { "name": "KPLCE", "url": "https://www.uniprot.org/uniprotkb/G3N3D3", "locus": { "chromosome": "3", "start_pos": 18070245, "end_pos": 18072217, "strand": "+", "evidence": [ { "database": "Ensembl Gene", "id": "ENSBTAG00000046138", "url": "https://www.ensembl.org/id/ENSBTAG00000046138" } ] } } ], "crossref": [ { "id": "G3N3D3", "url": "https://alphafold.ebi.ac.uk/entry/G3N3D3", "database": "AlphaFoldDB", "categories": [] }, { "id": "ENSBTAG00000046138", "url": "https://bgee.org/?page=gene&gene_id=ENSBTAG00000046138", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "QTYVKCQ", "url": "https://omabrowser.org/oma/group/QTYVKCQ/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "G3N3D3", "url": "https://www.orthodb.org/?gene=G3N3D3", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "G3N3D3", "url": "https://www.uniprot.org/uniprotkb/G3N3D3", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "G3N3D3-1", "url": "https://www.uniprot.org/uniprotkb/G3N3D3-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MCDQQKQPEFPPSCVKGSGLGVVQSTKCTSVKCPPPCPTQTFVKCSPPCPTQTFVKCPGPCLTQTYMKCPPPCPTQNYAKCPVPFQTKTFVNCVTPCQTLVKCPAPSQTTYVKYPAPCQTFVKCPAPCQTTYGKAPAPCQTQTYYVQTPAPSQTYYTQAPVRGSVTSCCVPDPCSAPCSTSYCCLAPRTFGVSPLRRWIQRPQDCNSGSSGCCEDSGCCGSGCCSSGCCSSGCCGSGCCCLGIIPMRSRGPACCDCDDDCDC", "length": 262, "header": "tr|G3N3D3-1|G3N3D3_BOVIN Isoform 1 of KPRP N-terminal and LCE C-terminal like protein OS=Bos taurus OX=9913 GN=KPLCE PE=4 SV=2 CANONICAL=G3N3D3-1" }, "isoforms": [ { "isoform_ac": "G3N3D3-1", "url": "https://www.uniprot.org/uniprotkb/G3N3D3/entry", "sequence": { "sequence": "MCDQQKQPEFPPSCVKGSGLGVVQSTKCTSVKCPPPCPTQTFVKCSPPCPTQTFVKCPGPCLTQTYMKCPPPCPTQNYAKCPVPFQTKTFVNCVTPCQTLVKCPAPSQTTYVKYPAPCQTFVKCPAPCQTTYGKAPAPCQTQTYYVQTPAPSQTYYTQAPVRGSVTSCCVPDPCSAPCSTSYCCLAPRTFGVSPLRRWIQRPQDCNSGSSGCCEDSGCCGSGCCSSGCCSSGCCGSGCCCLGIIPMRSRGPACCDCDDDCDC", "length": 262, "header": "tr|G3N3D3-1|G3N3D3_BOVIN Isoform 1 of KPRP N-terminal and LCE C-terminal like protein OS=Bos taurus OX=9913 GN=KPLCE PE=4 SV=2 CANONICAL=G3N3D3-1" }, "locus": { "chromosome": "3", "start_pos": 18071330, "end_pos": 18070545, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000063124.3", "url": "https://www.ensembl.org/id/ENSBTAT00000063124.3" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000056436.2", "url": "https://www.ensembl.org/id/ENSBTAP00000056436.2" } ] } } ], "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "other", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 39, "start_aa": "Thr", "end_pos": 39, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr39", "evidence": [ { "id": "", "database": "GlyGen", "url": "https://data.glygen.org/" } ], "filter_code": "000000000000000010000.00000000001000.0.01000" }, { "glytoucan_ac": "", "type": "O-linked", "subtype": "other", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 51, "start_aa": "Thr", "end_pos": 51, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr51", "evidence": [ { "id": "", "database": "GlyGen", "url": "https://data.glygen.org/" } ], "filter_code": "000000000000000010000.00000000001000.0.01000" } ], "phosphorylation": [], "glycation": [], "keywords": [ "glycoprotein", "glycoprotein_predicted" ], "publication": [], "pathway": [], "orthologs": [ { "uniprot_canonical_ac": "F1M6N0-1", "protein_name": "KPRP N-terminal and LCE C-terminal like protein", "gene_name": "Kplce", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MCDQQKQPQFLPSCVKGSGMGVGQGSDGASGKGQVSGQIQTVDASGPAPCQPQTIVRYSAAVPAQTYVKYQVPCQTKTYVKCPTPCQTYVKCPAPCQTTYVKCPAPCQTTYVKCPAPCQTTYVKCPAPCQTTYVKCPAPCQTTYVKCPAPCQTTTVKCPAPCQTTSVKCPAPCQAQTYYVQYQAPGQTYYTQASSSGSGSQGCVPDPCSAPCSTSYCYLAPRTFGVSPLRRWVQRPQGWNTGSSSCCEDSGCCSSGGCGGCGSGGCGSGDCGGCGCGCGSGCCCLGIIPMRSRGPACCDHEDDCCC", "length": 306 }, "evidence": [ { "id": "G3N3D3", "url": "https://omabrowser.org/oma/group/G3N3D3/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "G5E8Z3-1", "protein_name": "KPRP N-terminal and LCE C-terminal like protein", "gene_name": "Kplce", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MCDQQKQPQFLPSCVKGSGLGVGQGSDGAFGKGQVSGQIQAVGAPGPAPYQPQTVVRYSAPVPAQTYVRYQVPCQTKTYVKCPTPCQTYVKCPAPCQTTYVKCPAPCQTTCVKCPAPCQKTYVKCPAPCQTTNVKCPAPCQTTSVKCPAPCQAQTYYVQYQVPYQTYYTQASSSGSGPQGCVPDPCSAPCSTSYCCLAPRSFGVSPLRRWIQRPQGWNTGSSSCCEDSGCCSSGGCGGCGGCGGCGGCNSCCGSGCCCLGIIPMRSRGPACCDHEDDCCC", "length": 280 }, "evidence": [ { "id": "G3N3D3", "url": "https://omabrowser.org/oma/group/G3N3D3/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q5T750-1", "protein_name": "Protein KPLCE", "gene_name": "KPLCE", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MCDQQKQPQFPPSCVKGSGLGAGQGSNGASVKCPVPCQTQTVCVTGPAPCPTQTYVKYQVPCQTQTYVKCPAPCQRTYVKYPTPCQTYVKCPAPCQTTYVKCPTPCQTYVKCPAPCQMTYIKSPAPCQTQTCYVQGASPCQSYYVQAPASGSTSQYCVTDPCSAPCSTSYCCLAPRTFGVSPLRRWIQRPQNCNTGSSGCCENSGSSGCCGSGGCGCSCGCGSSGCCCLGIIPMRSRGPACCDHEDDCCC", "length": 250 }, "evidence": [ { "id": "G3N3D3", "url": "https://omabrowser.org/oma/group/G3N3D3/", "database": "OMA" } ], 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"id": "G3N3E9", "url": "https://www.orthodb.org/?gene=G3N3E9", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR24241", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR24241", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR24241:SF1", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR24241:SF1", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00001", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00001", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "NP_001192364", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001192364", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "G3N3E9", "url": "https://www.uniprot.org/uniprotkb/G3N3E9", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "G3N3E9-1", "url": "https://www.uniprot.org/uniprotkb/G3N3E9-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MCFSPILEINMQSESNITVRDDIDDINTNMYQPLSYPLSFQVSLTGFLMLEIVLGLGSNLTVLVLYCMKSNLINSVSNIITMNLHVLDVIICVGCIPLTIVILLLSLESNTALICCFHEACVSFASVSTAINVFAITLDRYDISVKPANRILTMGRAAMLMISIWIFSFFSFLIPFIEVNFFSLQSGNTWENKTLLCVSTNEYYTELGMYYHLLVQIPIFFFTVIVMLITYSKILQALNIRIGTRFSTGQKKKARKKKTISLTTQHETTDMSQGSGGRNVVFGVRTSVSVIIALRRAMKRHRERRERQKRVFKMSLLIISTFLLCWTPISVLNTTILCLGPSDLLVKLRLCFLVMGYGTTIFHPLLYAFTRQKFQKVLKSKMKKRVVSIVEADPMPNNAVIHNSWIDPKRNKKLTFEDSEIREKCLVPQVVTD", "length": 433, "header": "tr|G3N3E9-1|G3N3E9_BOVIN Isoform 1 of G-protein coupled receptor 22 OS=Bos taurus OX=9913 GN=GPR22 PE=4 SV=2 CANONICAL=G3N3E9-1" }, "isoforms": [ { "isoform_ac": "G3N3E9-1", "url": "https://www.uniprot.org/uniprotkb/G3N3E9/entry", "sequence": { "sequence": "MCFSPILEINMQSESNITVRDDIDDINTNMYQPLSYPLSFQVSLTGFLMLEIVLGLGSNLTVLVLYCMKSNLINSVSNIITMNLHVLDVIICVGCIPLTIVILLLSLESNTALICCFHEACVSFASVSTAINVFAITLDRYDISVKPANRILTMGRAAMLMISIWIFSFFSFLIPFIEVNFFSLQSGNTWENKTLLCVSTNEYYTELGMYYHLLVQIPIFFFTVIVMLITYSKILQALNIRIGTRFSTGQKKKARKKKTISLTTQHETTDMSQGSGGRNVVFGVRTSVSVIIALRRAMKRHRERRERQKRVFKMSLLIISTFLLCWTPISVLNTTILCLGPSDLLVKLRLCFLVMGYGTTIFHPLLYAFTRQKFQKVLKSKMKKRVVSIVEADPMPNNAVIHNSWIDPKRNKKLTFEDSEIREKCLVPQVVTD", "length": 433, "header": "tr|G3N3E9-1|G3N3E9_BOVIN Isoform 1 of G-protein coupled receptor 22 OS=Bos taurus OX=9913 GN=GPR22 PE=4 SV=2 CANONICAL=G3N3E9-1" }, "locus": { "chromosome": "4", "start_pos": 48511136, "end_pos": 48509838, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000064577.4", "url": "https://www.ensembl.org/id/ENSBTAT00000064577.4" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000056452.2", "url": "https://www.ensembl.org/id/ENSBTAP00000056452.2" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [ { "id": "bta:783685", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?bta:783685", "resource": "KEGG Pathway" } ], "orthologs": [ { "uniprot_canonical_ac": "A0A8M9PMY9-1", "protein_name": "G-protein coupled receptor 22", "gene_name": "gpr22b", "tax_id": 7955, "organism": "Danio rerio", "sequence": { "sequence": "MHVPPAAEEESTMSNVTVLDITESVSPVMTAAGGPYPYPLSFQVSLTGFLMLEIVLGLSSNLTVLALYCMKSNLVNSVSNIVTMNLHVLDVLVCVCCIPLTIVVLMLSLQGDTVLVCCFHEACVSFASVATAANVLAITLDRYDISVKPANRVLTMGRAVALLGCIWVLSFVSFLVPFIEVGFLGPEPTLANQTAVVHVNEYYTELGLYYHLVAQIPIFCLTAVIMLMTYAKILQALNIRIGTRFHATQKKKKKLRRKKNFSLMSTSEQQLPEITDASQSSGGTRGNAPLGMRTSVSVIIALRRAVKRHRERRERQKRVFRMSLLIISTFLLCWTPITVLNTVILSAGPSDLTVKLRLGFLVMAYGTTVFHPLLYAFTRQKFQKVLKSKMKKRVVSISEADPLPNNAVIRNSWIDPKRNKKVTFDDHEARQKCLSSEDAD", "length": 440 }, "evidence": [ { "id": "G3N3E9", "url": "https://omabrowser.org/oma/group/G3N3E9/", "database": "OMA" } ], "glygen_name": "Zebrafish", "common_name": "Zebrafish" }, { "uniprot_canonical_ac": "D4A3U0-1", "protein_name": "G protein-coupled receptor 22", "gene_name": "Gpr22", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MCFSPVLEINMQSESNVTVRDDIEDIDTNMYQPLSYPLSFQVSLTGFLMLEIVLGLGSNLTVLVLYCMKSNLISSVSNIITMNLHVLDVIICVGCIPLTIVILLLSLERNTALICCFHEACVSFASVSTAINVFAITLDRYDISVKPANRILTMGRAVMLMTSIWIFSFFSFLIPFIEVNFFSLQSGNAWENKTLLCVSTSEYYTELGMYYHLLVQIPIFFFTVIVMLITYTKILQALNIRIGTRFSTGQKKKARKKKTISLTTHETTDMSQSSGGRNVVFGVRTSVSVIIALRRAVKRHRERRERQKRVFKMSLLIISTFLLCWTPISVLNTTILCLGPSDLLVKLRLCFLVMAYGTTIFHPLLYAFTRQKFQKVLKSKMKKRVVSIVEADPMPNNAVIHNSWIDPKRNKKVTYEDSEIREKCLVPQVVTD", "length": 432 }, "evidence": [ { "id": "G3N3E9", "url": "https://omabrowser.org/oma/group/G3N3E9/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "F1SAF1-1", "protein_name": "G-protein coupled receptor 22", "gene_name": "GPR22", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MCFSPILEINMQSESNITVRDDIDDINTNMYQPLSYPLSFQVSLTGFLMLEIVLGLGSNLTVLVLYCMKSNLINSVSNIITMNLHVLDVIICVGCIPLTIVILLLSLESNTALICCFHEACVSFASVSTAINVFAITLDRYDISVKPANRILTMGRAVMLMISIWIFSFFSFLIPFIEVNFFSLQSGNTWENKTLLCVSTNEYYTELGMYYHLLVQIPIFFFTVIVMLITYTKILQALNIRIGTRFSTGQKKKARKKKTISLTTQHETTDMSQSSGGRNVVFGVRTSVSVIIALRRAVKRHRERRERQKRVFKMSLLIISTFLLCWTPISVLNTTILCLGPSDLLVKLRLCFLVMGYGTTIFHPLLYAFTRQKFQKVLKSKMKKRVVSIVEADPMPNNAVIHNSWIDPKRNKKIPFEDSEIREKCLVPQVVTD", "length": 433 }, "evidence": [ { "id": "G3N3E9", "url": "https://omabrowser.org/oma/group/G3N3E9/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "Q8BZL4-1", "protein_name": "G protein-coupled receptor 22", "gene_name": "Gpr22", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MCFSPVLEINMQSESNVTVRDDIDDIDTNMYQPLSYPLSFQVSLTGFLMLEIVLGLGSNLTVLVLYCMKSNLINSVSNIITMNLHVLDVIICVGCIPLTIVILLLSLESNTALICCFHEACVSFASVSTAINVFAITLDRYDISVKPANRILTMGRAVMLMTSIWIFSFFSFLIPFIEVNFFSLQSGNTWANKTLLCVSTSEYYTELGMYYHLLVQIPIFFFTVIVMLITYTKILQALNIRIGTRFSTGQKKKARKKKTISLATHETTDMSQSSGGRNVVFGVRTSVSVIIALRRAVKRHRERRERQKRVFKMSLLIISTFLLCWTPISVLNTTILCLGPSDLLVKLRLCFLVMAYGTTIFHPLLYAFTRQKFQKVLKSKMKKRVVSIVEADPMPNNAVIHNSWIDPKRNKKVTYEDSEIREKCLVPQVVTD", "length": 432 }, "evidence": [ { "id": "G3N3E9", "url": "https://omabrowser.org/oma/group/G3N3E9/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q99680-1", "protein_name": "G protein-coupled receptor 22", "gene_name": "GPR22", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MCFSPILEINMQSESNITVRDDIDDINTNMYQPLSYPLSFQVSLTGFLMLEIVLGLGSNLTVLVLYCMKSNLINSVSNIITMNLHVLDVIICVGCIPLTIVILLLSLESNTALICCFHEACVSFASVSTAINVFAITLDRYDISVKPANRILTMGRAVMLMISIWIFSFFSFLIPFIEVNFFSLQSGNTWENKTLLCVSTNEYYTELGMYYHLLVQIPIFFFTVVVMLITYTKILQALNIRIGTRFSTGQKKKARKKKTISLTTQHEATDMSQSSGGRNVVFGVRTSVSVIIALRRAVKRHRERRERQKRVFRMSLLIISTFLLCWTPISVLNTTILCLGPSDLLVKLRLCFLVMAYGTTIFHPLLYAFTRQKFQKVLKSKMKKRVVSIVEADPLPNNAVIHNSWIDPKRNKKITFEDSEIREKCLVPQVVTD", "length": 433 }, "evidence": [ { "id": "G3N3E9", "url": "https://omabrowser.org/oma/group/G3N3E9/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" } ], "go_annotation": { "categories": [ { "name": "Molecular Function", "total": 1, "go_terms": [ { "name": "G protein-coupled receptor activity", "id": "GO:0004930", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0004930", "evidence": [ { "database": "UniProtKB", "id": "G3N3E9", "url": "https://www.uniprot.org/uniprotkb/G3N3E9" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 1, "go_terms": [ { "name": "plasma membrane", "id": "GO:0005886", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005886", "evidence": [ { "database": "UniProtKB", "id": "G3N3E9", "url": "https://www.uniprot.org/uniprotkb/G3N3E9" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 3, "go_terms": [ { "name": "G protein-coupled receptor signaling pathway", "id": "GO:0007186", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007186", "evidence": [ { "database": "UniProtKB", "id": "G3N3E9", "url": "https://www.uniprot.org/uniprotkb/G3N3E9" } ], "pmid": "" }, { "name": "cellular response to hormone stimulus", "id": "GO:0032870", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0032870", "evidence": [ { "database": "UniProtKB", "id": "G3N3E9", "url": "https://www.uniprot.org/uniprotkb/G3N3E9" } ], "pmid": "" }, { "name": "cell projection organization", "id": "GO:0030030", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030030", "evidence": [ { "database": "UniProtKB", "id": "G3N3E9", "url": "https://www.uniprot.org/uniprotkb/G3N3E9" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 16, "end_pos": 18, "annotation": "n_glycosylation_sequon" }, { "start_pos": 192, "end_pos": 194, "annotation": "n_glycosylation_sequon" }, { "start_pos": 333, "end_pos": 335, "annotation": "n_glycosylation_sequon" }, { "start_pos": 59, "end_pos": 61, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "G3N3E9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3N3E9" }, { "id": "PS50262", "database": "PROSITE", "url": "https://prosite.expasy.org/PS50262" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "G-protein coupled receptors family 1 profile", "eco_id": "ECO_0000259", "start_pos": 58, "end_pos": 367, "start_aa": "Ser", "end_aa": "Tyr", "glycosite_overlap": [] } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "homologset.oma", "label": "OMA Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 16, "end_pos": 18 }, { "start_pos": 192, "end_pos": 194 }, { "start_pos": 333, "end_pos": 335 }, { "start_pos": 59, "end_pos": 61 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": 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"https://www.ncbi.nlm.nih.gov/gene/617845", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR000626", "url": "https://www.ebi.ac.uk/interpro/entry/IPR000626", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR006636", "url": "https://www.ebi.ac.uk/interpro/entry/IPR006636", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR009060", "url": "https://www.ebi.ac.uk/interpro/entry/IPR009060", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR015496", "url": "https://www.ebi.ac.uk/interpro/entry/IPR015496", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR015940", "url": "https://www.ebi.ac.uk/interpro/entry/IPR015940", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR029071", "url": "https://www.ebi.ac.uk/interpro/entry/IPR029071", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "LLWFMPC", "url": "https://omabrowser.org/oma/group/LLWFMPC/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "G3N3K4", "url": "https://www.orthodb.org/?gene=G3N3K4", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR10677", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR10677", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR10677:SF4", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR10677:SF4", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00240", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00240", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF00627", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00627", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF23195", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF23195", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "NP_001033672", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001033672", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "G3N3K4", "url": "https://www.uniprot.org/uniprotkb/G3N3K4", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "G3N3K4-1", "url": "https://www.uniprot.org/uniprotkb/G3N3K4-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MAKSGEALPQGSPALVQDPHLIKVTVKTPKDKEDFSVTDTCTIQQLKEEISQRFKAHPDQLILIFAGKILKDPDSLAQCGVRDGLTVHLVIKMQRRTMGNECPAASVPTPAPSPGSLPQPSSIYPADGPPTFSLGVLTGLNGLGLTLGGFPDQPSSLVWQHVSVPEFVAQIIDDPFIQGLLSNTGLVRQLVLDNPRMQQLIQHNPEIGHILNNPEIMRQTLEFLRNPAMMQEMMRSQDRALSNLESIPGGYNVLRTMYTDIMDPMLNAVQEQFGGNPFATTNANATTSSSQPSRMENCDPLPNPWTSTYAGSAGRRGRRPGDQDIYELRNRVPNILGNIGLYDYLQQLHETPQSLGSYLQGMASTLSPSQEQPPPPPGNQVPPASPSSQKPESGQALPKESVAIKGKPSCPALLRYPTESSARKDGGQDGAGNGSTGHSIHMPDLVSGLGPAANRTQIVPSPPLPTAAAAGTPERVWPPPLAYPRSLRPTSMNQAPQLQDEMHWQLPLLLHLQAAMANPRAMHALLQIEQGLQILATEAPRLFLWFMPCLTGLGSMAGDTEARESPLVPEDPLPPPAPEVPSAQGSMELGLHSTPFLQMLQALTGTNPQQPTPETHFRVQLEQLRAMGFLNPEANLQALIATGGDVDAAVEKLRQL", "length": 656, "header": "tr|G3N3K4-1|G3N3K4_BOVIN Isoform 1 of Ubiquilin-3 OS=Bos taurus OX=9913 GN=UBQLN3 PE=4 SV=3 CANONICAL=G3N3K4-1" }, "isoforms": [ { "isoform_ac": "G3N3K4-1", "url": "https://www.uniprot.org/uniprotkb/G3N3K4/entry", "sequence": { "sequence": "MAKSGEALPQGSPALVQDPHLIKVTVKTPKDKEDFSVTDTCTIQQLKEEISQRFKAHPDQLILIFAGKILKDPDSLAQCGVRDGLTVHLVIKMQRRTMGNECPAASVPTPAPSPGSLPQPSSIYPADGPPTFSLGVLTGLNGLGLTLGGFPDQPSSLVWQHVSVPEFVAQIIDDPFIQGLLSNTGLVRQLVLDNPRMQQLIQHNPEIGHILNNPEIMRQTLEFLRNPAMMQEMMRSQDRALSNLESIPGGYNVLRTMYTDIMDPMLNAVQEQFGGNPFATTNANATTSSSQPSRMENCDPLPNPWTSTYAGSAGRRGRRPGDQDIYELRNRVPNILGNIGLYDYLQQLHETPQSLGSYLQGMASTLSPSQEQPPPPPGNQVPPASPSSQKPESGQALPKESVAIKGKPSCPALLRYPTESSARKDGGQDGAGNGSTGHSIHMPDLVSGLGPAANRTQIVPSPPLPTAAAAGTPERVWPPPLAYPRSLRPTSMNQAPQLQDEMHWQLPLLLHLQAAMANPRAMHALLQIEQGLQILATEAPRLFLWFMPCLTGLGSMAGDTEARESPLVPEDPLPPPAPEVPSAQGSMELGLHSTPFLQMLQALTGTNPQQPTPETHFRVQLEQLRAMGFLNPEANLQALIATGGDVDAAVEKLRQL", "length": 656, "header": "tr|G3N3K4-1|G3N3K4_BOVIN Isoform 1 of Ubiquilin-3 OS=Bos taurus OX=9913 GN=UBQLN3 PE=4 SV=3 CANONICAL=G3N3K4-1" }, "locus": { "chromosome": "15", "start_pos": 48061536, "end_pos": 48059569, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000035442.6", "url": "https://www.ensembl.org/id/ENSBTAT00000035442.6" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000056507.3", "url": "https://www.ensembl.org/id/ENSBTAP00000056507.3" } ] } } ], "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "other", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 109, "start_aa": "Thr", "end_pos": 109, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr109", "evidence": [ { "id": "", "database": "GlyGen", "url": "https://data.glygen.org/" } ], "filter_code": "000000000000000010000.00000000001000.0.01000" }, { "glytoucan_ac": "", "type": "O-linked", "subtype": "other", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 466, "start_aa": "Thr", "end_pos": 466, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr466", "evidence": [ { "id": "", "database": "GlyGen", "url": "https://data.glygen.org/" } ], "filter_code": "000000000000000010000.00000000001000.0.01000" }, { "glytoucan_ac": "", "type": "O-linked", "subtype": "other", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 612, "start_aa": "Thr", "end_pos": 612, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr612", "evidence": [ { "id": "", "database": "GlyGen", "url": "https://data.glygen.org/" } ], "filter_code": "000000000000000010000.00000000001000.0.01000" } ], "phosphorylation": [], "glycation": [], "keywords": [ "glycoprotein", "glycoprotein_predicted" ], "publication": [], "pathway": [], "orthologs": [ { "uniprot_canonical_ac": "F7EYK8-1", "protein_name": "Ubiquilin-3", "gene_name": "Ubqln3", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MIFVSHPHPLSCVPTDLGLLLPIMAKSGEALPQGSPAPVQDSQLIRVTVKTPKDKEDFSVVDTCTIRQLKEKISHRFKAHPNQLVLIFAGKILKDPDSLAQCGVRDGLTVHLVIKMQRRTTGTECPAPPVSTPGPNPLELPQPNSAYPVDGSPSFSLGVLTGLSGLGLTSGSFSDQPGSLMWQHMSVPELVAQLVDDPFIQGLLSNTGLMRQLVLDNPHMQQLIQQNPEIGHILNNPEIMRQTMEFLRNPSMMQEMMRSQDRALSNLESIPGGYNVLRTMYTDIMDPMLNAVQEQFGGNPFATATTASTTTTSSQPSRTENCDPLPNPWTSTCGVSGSRQGRQPGDQDTSESRNRLPSFLGNIGLFDYLQQLHETSQALGSYLQGTVPTPSSSQETPLSGNRVPPNLPPSPKPGSGQPLPKDSVAIKGKSSCPAFLRHSSENSTGQGGSLHDSGKSSTGPSTGLPNLTSQIGDNANRSPFVSTPSSLISPTPGAPESPWLPPTGYPRSLRSALTNQVPRMQNELHQQLPLLLHLQTAMTNPRVMQALLQIEQGLQILATEAPRLLLWFMPCLAGLSGVIGGTESREGVVMSEDPRPTPTSQISLVQGSAELGFHSSPFLQVLQALASTNPQQLQLEAHFRVQLEQLRAMGFLNLEANLQALIATGGDVDAAVEKLRKS", "length": 678 }, "evidence": [ { "id": "G3N3K4", "url": "https://omabrowser.org/oma/group/G3N3K4/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "Q8C5U9-1", "protein_name": "Ubiquilin-3", "gene_name": "Ubqln3", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MAKSGEALPQGSLAPAQDSQLIRVTVKTPKDKEDFSVVDTCTIRQLKEKISHRFKAHPNQLVLIFAGKILKDPDSLAQCGVRDGLTVHLVIKMQRRTIGTECPSPPVSIPGPNPGEIPQSSSVYSVDGSPSFSLGVLTGLSGLGLTSGSFSDQPGSLMWQHISVPELVAQLVDDPFIQGLLSNTGLVRQLVLDNPHMQHLIQQNPEIGHILNNPEIMRQTMEFLRNPSMMQEMMRSQDRALSNLESIPGGYNVLRTMYTDIMDPMLNAVQEQFGGNPFVTATTASTTTTSSQPSRTENCDPLPNPWTSTYGVSGGRQGRGGRQSGDQDASENRNRLPSFLGNIGLFDYLQQLHETSQSLESYLQGTVPTSNPSQESPLSGNRVPPTLPSSPKSGSGQSLPKESVAIKGKSSCPAFLRHSTENSTGQGGSLHDAGKGSTGPSTSLPNLTSQIGDSANRSSFVSTPSSLMSATPGVPESPWLPPTGYSRSLRSAGTNQVPRIQNEIHQQLPLLLHLQTAMANPRVMQALLQIEQGLQILATEAPRLLLWFMPCLTGLNGVTGGTEAREGVVMSEDPRPTPTPQISLAQGSTELGIHSSPFLQVLQALASTNPQQLQLEAHFRVQLEQLRAMGFLNLEANLQALIATEGDVDAAVEKLRKS", "length": 658 }, "evidence": [ { "id": "G3N3K4", "url": "https://omabrowser.org/oma/group/G3N3K4/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q9H347-1", "protein_name": "Ubiquilin-3", "gene_name": "UBQLN3", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MAKGGEALPQGSPAPVQDPHLIKVTVKTPKDKEDFSVTDTCTIQQLKEEISQRFKAHPDQLVLIFAGKILKDPDSLAQCGVRDGLTVHLVIKRQHRAMGNECPAASVPTQGPSPGSLPQPSSIYPADGPPAFSLGLLTGLSRLGLAYRGFPDQPSSLMRQHVSVPEFVTQLIDDPFIPGLLSNTGLVRQLVLDNPHMQQLIQHNPEIGHILNNPEIMRQTLEFLRNPAMMQEMIRSQDRVLSNLESIPGGYNVLCTMYTDIMDPMLNAVQEQFGGNPFATATTDNATTTTSQPSRMENCDPLPNPWTSTHGGSGSRQGRQDGDQDAPDIRNRFPNFLGIIRLYDYLQQLHENPQSLGTYLQGTASALSQSQEPPPSVNRVPPSSPSSQEPGSGQPLPEESVAIKGRSSCPAFLRYPTENSTGQGGDQDGAGKSSTGHSTNLPDLVSGLGDSANRVPFAPLSFSPTAAIPGIPEPPWLPSPAYPRSLRPDGMNPAPQLQDEIQPQLPLLMHLQAAMANPRALQALRQIEQGLQVLATEAPRLLLWFMPCLAGTGSVAGGIESREDPLMSEDPLPNPPPEVFPALDSAELGFLSPPFLHMLQDLVSTNPQQLQPEAHFQVQLEQLRSMGFLNREANLQALIATGGDVDAAVEKLRQS", "length": 655 }, "evidence": [ { "id": "G3N3K4", "url": "https://omabrowser.org/oma/group/G3N3K4/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" } ], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 1, "go_terms": [ { "name": "cytosol", "id": "GO:0005829", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005829", "evidence": [ { "database": "UniProtKB", "id": "G3N3K4", "url": "https://www.uniprot.org/uniprotkb/G3N3K4" } ], "pmid": "" } ] }, { "name": "Molecular Function", "total": 1, "go_terms": [ { "name": "polyubiquitin modification-dependent protein binding", "id": "GO:0031593", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0031593", "evidence": [ { "database": "UniProtKB", "id": "G3N3K4", "url": "https://www.uniprot.org/uniprotkb/G3N3K4" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 1, "go_terms": [ { "name": "ubiquitin-dependent protein catabolic process", "id": "GO:0006511", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006511", "evidence": [ { "database": "UniProtKB", "id": "G3N3K4", "url": "https://www.uniprot.org/uniprotkb/G3N3K4" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 284, "end_pos": 286, "annotation": "n_glycosylation_sequon" }, { "start_pos": 433, "end_pos": 435, "annotation": "n_glycosylation_sequon" }, { "start_pos": 454, "end_pos": 456, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [ { "pdb_id": "AF-G3N3K4-F1", "pdb_chain": "global", "start_pos": 1, "end_pos": 656, "overlap": "1.0", "method": "AlphaFold", "type": "alphafold", "resolution": -1.0, "url": "https://data.glygen.org/ln2downloads/pdb/current/AF-G3N3K4-F1.pdb", "url_external": "https://alphafold.ebi.ac.uk/entry/G3N3K4" } ], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "G3N3K4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3N3K4" }, { "id": "PS50030", "database": "PROSITE", "url": "https://prosite.expasy.org/PS50030" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "UBA", "eco_id": "ECO_0000259", "start_pos": 611, "end_pos": 656, "start_aa": "Pro", "end_aa": "Leu", "glycosite_overlap": [] }, { "evidence": [ { "id": "G3N3K4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3N3K4" }, { "id": "PS50053", "database": "PROSITE", "url": "https://prosite.expasy.org/PS50053" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "Ubiquitin-like", "eco_id": "ECO_0000259", "start_pos": 22, "end_pos": 96, "start_aa": "Ile", "end_aa": "Arg", "glycosite_overlap": [] } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "homologset.oma", "label": "OMA Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [ 109, 466, 612 ], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 284, "end_pos": 286 }, { "start_pos": 433, "end_pos": 435 }, { "start_pos": 454, "end_pos": 456 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 3 }, { "field": "total_sites", "count": 3 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 3 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "exact_sites", "count": 3 }, { "field": "exact_o_linked_sites", "count": 3 }, { "field": "fuzzy_sites", "count": 0 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_pos", "start_aa", "end_pos", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 3 }, { "field": "total_sites", "count": 3 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 3 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "exact_sites", "count": 3 }, { "field": "exact_o_linked_sites", "count": 3 }, { "field": "fuzzy_sites", "count": 0 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_pos", "start_aa", "end_pos", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ], "tool_support": { "graph_view": "yes" } }, { "uniprot_canonical_ac": "G3N3L6-1", "uniprot_ac": "G3N3L6", "uniprot_id": "G3N3L6_BOVIN", "mass": { "chemical_mass": 30530.0, "monoisotopic_mass": 30530.0 }, "refseq": {}, "gene_names": [ { "name": "TIMM29", "type": "recommended", "evidence": [ { "id": "G3N3L6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3N3L6" } ] } ], "protein_names": [ { "name": "Translocase of inner mitochondrial membrane 29", "type": "synonym", "evidence": [ { "id": "G3N3L6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3N3L6/entry#names_and_taxonomy" } ] } ], "function": [], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Bos taurus", "taxid": 9913, "evidence": [ { "database": "UniProtKB", "id": "G3N3L6", "url": "https://www.uniprot.org/uniprotkb/G3N3L6" } ], "common_name": "Bovine", "glygen_name": "Bovine", "reference_species": "Bos taurus [9913]" } ], "gene": [ { "name": "TIMM29", "url": "https://www.uniprot.org/uniprotkb/G3N3L6", "locus": { "chromosome": "7", "start_pos": 15370401, "end_pos": 15368348, "strand": "-", "evidence": [ { "database": "Ensembl Gene", "id": "ENSBTAG00000045893", "url": "https://www.ensembl.org/id/ENSBTAG00000045893" } ] } } ], "crossref": [ { "id": "G3N3L6", "url": "https://alphafold.ebi.ac.uk/entry/G3N3L6", "database": "AlphaFoldDB", "categories": [] }, { "id": "ENSBTAG00000045893", "url": "https://bgee.org/?page=gene&gene_id=ENSBTAG00000045893", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "IPR019322", "url": "https://www.ebi.ac.uk/interpro/entry/IPR019322", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "WRLKWKM", "url": "https://omabrowser.org/oma/group/WRLKWKM/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "PTHR21435", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR21435", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR21435:SF1", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR21435:SF1", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF10171", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF10171", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "G3N3L6", "url": "https://www.uniprot.org/uniprotkb/G3N3L6", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "G3N3L6-1", "url": "https://www.uniprot.org/uniprotkb/G3N3L6-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MVFLFGVRTPSRKTMAAAALKRFWSRSRREARDAAAAKPGVWARLGAWARSLLQDYAEACKDAAAAARARPGKAAVYLGLLGGAAACCSLAPSEAAFEEALLDASGTLLLLAPATRNRDSEAFVQRLLWLRGRGCLRHVSLGLFSLVYEAPFDAQASLYQARCRYLQPRWTDFPDRILDVGFVGRWWVLGARMRDSDINDDEFLHLPAHLRVVGPHQLHSEANERLFDEKYKPVVLTDDQVDQALWEDHVLQKEKKDQLALSQADSLLPSEAAR", "length": 274, "header": "tr|G3N3L6-1|G3N3L6_BOVIN Isoform 1 of Translocase of inner mitochondrial membrane 29 OS=Bos taurus OX=9913 GN=TIMM29 PE=4 SV=2 CANONICAL=G3N3L6-1" }, "isoforms": [ { "isoform_ac": "G3N3L6-1", "url": "https://www.uniprot.org/uniprotkb/G3N3L6/entry", "sequence": { "sequence": "MVFLFGVRTPSRKTMAAAALKRFWSRSRREARDAAAAKPGVWARLGAWARSLLQDYAEACKDAAAAARARPGKAAVYLGLLGGAAACCSLAPSEAAFEEALLDASGTLLLLAPATRNRDSEAFVQRLLWLRGRGCLRHVSLGLFSLVYEAPFDAQASLYQARCRYLQPRWTDFPDRILDVGFVGRWWVLGARMRDSDINDDEFLHLPAHLRVVGPHQLHSEANERLFDEKYKPVVLTDDQVDQALWEDHVLQKEKKDQLALSQADSLLPSEAAR", "length": 274, "header": "tr|G3N3L6-1|G3N3L6_BOVIN Isoform 1 of Translocase of inner mitochondrial membrane 29 OS=Bos taurus OX=9913 GN=TIMM29 PE=4 SV=2 CANONICAL=G3N3L6-1" }, "locus": { "chromosome": "7", "start_pos": 15369429, "end_pos": 15368533, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000065916.3", "url": "https://www.ensembl.org/id/ENSBTAT00000065916.3" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000056521.2", "url": "https://www.ensembl.org/id/ENSBTAP00000056521.2" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [], "orthologs": [ { "uniprot_canonical_ac": "Q8BGX2-1", "protein_name": 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"MAAAALRRFWSRRRAEAGDAVVAKPGVWARLGSWARALLRDYAEACRDASAEARARPGRAAVYVGLLGGAAACFTLAPSEGAFEEALLEASGTLLLLAPATRNRESEAFVQRLLWLRGRGRLRYVNLGLCSLVYEAPFDAQASLYQARCRYLQPRWTDFPGRVLDVGFVGRWWVLGAWMRDCDINDDEFLHLPAHLRVVGPQQLHSETNERLFDEKYKPVVLTDDQVDQALWEEQVLQKEKKDRLALSQAHSLVQAEAPR", "length": 260 }, "evidence": [ { "id": "G3N3L6", "url": "https://omabrowser.org/oma/group/G3N3L6/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" } ], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 2, "go_terms": [ { "name": "mitochondrial intermembrane space", "id": "GO:0005758", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005758", "evidence": [ { "database": "UniProtKB", "id": "G3N3L6", "url": "https://www.uniprot.org/uniprotkb/G3N3L6" } ], "pmid": "" }, { "name": "TIM22 mitochondrial import inner membrane insertion complex", "id": "GO:0042721", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0042721", "evidence": [ { "database": "UniProtKB", "id": "G3N3L6", "url": "https://www.uniprot.org/uniprotkb/G3N3L6" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 1, "go_terms": [ { "name": "protein insertion into mitochondrial inner membrane", "id": "GO:0045039", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0045039", "evidence": [ { "database": "UniProtKB", "id": "G3N3L6", "url": "https://www.uniprot.org/uniprotkb/G3N3L6" } ], "pmid": "" } ] }, { "name": "Molecular Function", "total": 1, "go_terms": [ { "name": "protein transporter activity", "id": "GO:0140318", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0140318", "evidence": [ { "database": "UniProtKB", "id": "G3N3L6", "url": "https://www.uniprot.org/uniprotkb/G3N3L6" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [ { "pdb_id": "AF-G3N3L6-F1", "pdb_chain": "global", "start_pos": 1, "end_pos": 274, "overlap": "1.0", "method": "AlphaFold", "type": "alphafold", "resolution": -1.0, "url": "https://data.glygen.org/ln2downloads/pdb/current/AF-G3N3L6-F1.pdb", "url_external": "https://alphafold.ebi.ac.uk/entry/G3N3L6" } ], "lectin_list": [], "domain_list": [], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "homologset.oma", "label": "OMA Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { 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"url": "https://www.uniprot.org/uniprotkb/G3N3Q7" } ], "common_name": "Bovine", "glygen_name": "Bovine", "reference_species": "Bos taurus [9913]" } ], "gene": [ { "name": "C28H10orf105", "url": "https://www.uniprot.org/uniprotkb/G3N3Q7", "locus": { "chromosome": "28", "start_pos": 27862535, "end_pos": 27873884, "strand": "+", "evidence": [ { "database": "Ensembl Gene", "id": "ENSBTAG00000045826", "url": "https://www.ensembl.org/id/ENSBTAG00000045826" } ] } } ], "crossref": [ { "id": "ENSBTAG00000045826", "url": "https://bgee.org/?page=gene&gene_id=ENSBTAG00000045826", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "101904363", "url": "https://www.ncbi.nlm.nih.gov/gene/101904363", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR039954", "url": "https://www.ebi.ac.uk/interpro/entry/IPR039954", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "bta:101904363", "url": "https://www.genome.jp/dbget-bin/www_bget?bta:101904363", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "HECMPYH", "url": "https://omabrowser.org/oma/group/HECMPYH/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "G3N3Q7", "url": "https://www.orthodb.org/?gene=G3N3Q7", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR38325", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR38325", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR38325:SF1", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR38325:SF1", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF17665", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF17665", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "XP_015316521", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_015316521", "database": "RefSeq", 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SV=1 CANONICAL=G3N3Q7-1" }, "locus": { "chromosome": "28", "start_pos": 27863599, "end_pos": 27863231, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000126439.1", "url": "https://www.ensembl.org/id/ENSBTAT00000126439.1" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000078809.1", "url": "https://www.ensembl.org/id/ENSBTAP00000078809.1" } ] } } ], "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "other", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 17, "start_aa": "Thr", "end_pos": 17, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr17", "evidence": [ { "id": "", "database": "GlyGen", "url": "https://data.glygen.org/" } ], "filter_code": "000000000000000010000.00000000001000.0.01000" } ], "phosphorylation": [], 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"categories": [] }, { "id": "ENSBTAG00000045776", "url": "https://bgee.org/?page=gene&gene_id=ENSBTAG00000045776", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "IPR031714", "url": "https://www.ebi.ac.uk/interpro/entry/IPR031714", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "PTHR41401", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR41401", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR41401:SF1", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR41401:SF1", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF15855", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF15855", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "G3N3T5", "url": "https://www.uniprot.org/uniprotkb/G3N3T5", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "G3N3T5-1", "url": "https://www.uniprot.org/uniprotkb/G3N3T5-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MLAATTALSPLHGRAGDIRPGPLPGGSDASSHLPVQEARPHLRAGQLKGTATPKRIEGDRWGRGGALLCRVLAQRWGPGGGGGRKGGGGRAAQAEMEWGPGSDWSRGEAAGVDRGKAGLGLGGRPPPQPPRDERAQQLLDAVEQRQRQLLDTIAACEEMLRQLGRRRPEPAGGGVSAHPGLGLGGGDCPLAALAKPWLPLEGGRVSPLLNPLLPFIWTRGFEKNVSAKPGAPSQPAVSSRGGFPKDASDGAAEP", "length": 254, "header": "tr|G3N3T5-1|G3N3T5_BOVIN Isoform 1 of Chromosome 3 C1orf122 homolog OS=Bos taurus OX=9913 GN=C3H1orf122 PE=4 SV=3 CANONICAL=G3N3T5-1" }, "isoforms": [ { "isoform_ac": "G3N3T5-1", "url": "https://www.uniprot.org/uniprotkb/G3N3T5/entry", "sequence": { "sequence": "MLAATTALSPLHGRAGDIRPGPLPGGSDASSHLPVQEARPHLRAGQLKGTATPKRIEGDRWGRGGALLCRVLAQRWGPGGGGGRKGGGGRAAQAEMEWGPGSDWSRGEAAGVDRGKAGLGLGGRPPPQPPRDERAQQLLDAVEQRQRQLLDTIAACEEMLRQLGRRRPEPAGGGVSAHPGLGLGGGDCPLAALAKPWLPLEGGRVSPLLNPLLPFIWTRGFEKNVSAKPGAPSQPAVSSRGGFPKDASDGAAEP", "length": 254, "header": "tr|G3N3T5-1|G3N3T5_BOVIN Isoform 1 of Chromosome 3 C1orf122 homolog OS=Bos taurus OX=9913 GN=C3H1orf122 PE=4 SV=3 CANONICAL=G3N3T5-1" }, "locus": { "chromosome": "3", "start_pos": 108109056, "end_pos": 108108090, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000063550.3", "url": "https://www.ensembl.org/id/ENSBTAT00000063550.3" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000056596.3", "url": "https://www.ensembl.org/id/ENSBTAP00000056596.3" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [], "orthologs": [], "go_annotation": {}, "pro_annotation": [], "site_annotation": [ { "start_pos": 224, "end_pos": 226, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [ { "pdb_id": "AF-G3N3T5-F1", "pdb_chain": "global", "start_pos": 1, "end_pos": 254, "overlap": "1.0", "method": "AlphaFold", "type": "alphafold", "resolution": -1.0, "url": "https://data.glygen.org/ln2downloads/pdb/current/AF-G3N3T5-F1.pdb", "url_external": "https://alphafold.ebi.ac.uk/entry/G3N3T5" } ], "lectin_list": [], "domain_list": [], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 224, "end_pos": 226 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ], "tool_support": { "graph_view": "yes" } }, { "uniprot_canonical_ac": "G3N3V6-1", "uniprot_ac": "G3N3V6", "uniprot_id": "G3N3V6_BOVIN", "mass": { "chemical_mass": 151772.0, "monoisotopic_mass": 151772.0 }, "refseq": { "ac": "NP_001178432", "name": "zinc finger protein 804B", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001178432" }, "gene_names": [ { "name": "ZNF804B", "type": "recommended", "evidence": [ { "id": "G3N3V6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3N3V6" } ] }, { "name": "ZNF804B", "type": "synonym", "evidence": [ { "id": "NP_001178432", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001178432" } ] } ], "protein_names": [ { "name": "Zinc finger protein 804B", "type": "synonym", "evidence": [ { "id": "G3N3V6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3N3V6/entry#names_and_taxonomy" } ] }, { "name": "zinc finger protein 804B", "type": "synonym", "evidence": [ { "id": "NP_001178432", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001178432" } ] } ], "function": [], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Bos taurus", "taxid": 9913, "evidence": [ { "database": "UniProtKB", "id": "G3N3V6", "url": "https://www.uniprot.org/uniprotkb/G3N3V6" } ], "common_name": "Bovine", "glygen_name": "Bovine", "reference_species": "Bos taurus [9913]" } ], "gene": [ { "name": "ZNF804B", "url": "https://www.uniprot.org/uniprotkb/G3N3V6", "locus": { "chromosome": "4", "start_pos": 73427122, "end_pos": 72859147, "strand": "-", "evidence": [ { "database": "Ensembl Gene", "id": "ENSBTAG00000046430", "url": "https://www.ensembl.org/id/ENSBTAG00000046430" } ] } } ], "crossref": [ { "id": "ENSBTAG00000046430", "url": "https://bgee.org/?page=gene&gene_id=ENSBTAG00000046430", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "100295505", "url": "https://www.ncbi.nlm.nih.gov/gene/100295505", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR013087", "url": "https://www.ebi.ac.uk/interpro/entry/IPR013087", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR036236", "url": "https://www.ebi.ac.uk/interpro/entry/IPR036236", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR052445", "url": "https://www.ebi.ac.uk/interpro/entry/IPR052445", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "bta:100295505", "url": "https://www.genome.jp/dbget-bin/www_bget?bta:100295505", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "PTHR17614", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR17614", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR17614:SF12", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR17614:SF12", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF27597", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF27597", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "R-BTA-212436", "url": "https://www.reactome.org/PathwayBrowser/#R-BTA-212436", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": 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"MACYLVISSRHLSNGHYRGIKGVFRGPLCKNGSPSPDFPEKEKSTAKALEDVKANFYCELCDKQYHKHQEFDNHINSYDHAHKQRLKELKQREFARNVASKSWKDEKKQEKALKRLHQLAELRQQSECVSENGPAYKASKVPIEKQLQQGIFPVKNGRKVSCMKNALLLKGKNLSRSIADKQRSTTANRHQLQTDRRRLFGNRVPQTSSDLSNANQRTGVSFSFSKKVHLKLESSASVFSENTEETHDCNKSPIYKTKSTAEKCMCCRFANEDTHLTKEKDINISSNHLESILHNTLPINSQILQDKNDFVDEMLENSIGIHASFSKSNIHLSDVDFTPSSRAKETRNTLKNTSENRISHSCQANVSSSPTNIYKHSDARVFGCLGEIPSIEPSEQSSSVHLNPNSRKQKREKSLDKTERVSRNAQSFIREAYPHDVKAKALPFLHVKSKDGHTTLQWPTELLLFTKTEPCISYGCNPLYFDFKLSRNTKDGRDPEDLKTELQKEASEMKTTMENQVSGLIKDQQKLIQEDNRSLKPKMKIANPDWENFQRKYNLGGNNSEPSMSERNFSASDLEMKNPEVPAYLDISLKNCVGNNKNGGNELQEPSRAHWQSCQRVILNDANKGLSFSPCTSRTKKHKLISCDPHLDVEEVNQFTWKSSPYTIRDHSDHGKDFSVILNSNYISTTSGVSGCGRASYKISSPKVSLNRCSSPSDTSHVSTSSLRSSHSNYGSSGHDRGNLLYFCKREHNSVERHKRKRRKHSCFCFSEELAKSDCPQSETERGRSCKLWESIKNEKYSKHAYGYCREKHKLGKNQQFSGQKSKRITQCDFSSQVFCAGNSENPPNCQGPQHSRLGSHSREKMYYLNKSKMNQQSLDSPHICDLGKVKPMQCNSGNISYLLRNCSRSPSDTTELNPIEGERTSLTAKSLLERVQAKKCQEQSIQFEISSNSCKNESETLSQIQCVIPFTPPGCNRPSLPLPEKTPNKGRRRKDKGSAMQRSIDKNKVKSSPTNDFTVLVGTDCDNHFSKGIIHVVAESHSPNMKKNPTTKEQPKSLINEVQPSIQSCDPVPNGFPGAFPSNRYSGITDSMETKENDMNLDLQDGSMQMNQIEGNINSYYDRTMQKHDKVADDLEVCHKSLSPPLIQQPITYSPDEIDKYKLLQLQAQQHMQKQLLSKHLRVLPAAGPTAFSSASTVQTVPGHQQASITTIHHTFLQHIVSASINAHSSHLPIAHLHPLSQPRFNPFTFSPLTPTVIPAHPTFLAGHPLHLVTTAPFHPSHITFQPLPPAAFIPTLFGPHFNPATTSIIHLNPLIQPVFQGQDLCHHSCSSQMQPLNGVKEALNVSARLN", 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"Protein Classification" ] }, { "id": "PF15831", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF15831", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "G3N3X8", "url": "https://www.uniprot.org/uniprotkb/G3N3X8", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "G3N3X8-1", "url": "https://www.uniprot.org/uniprotkb/G3N3X8-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MDRMLSKYSWKMEFWENPWDQGGLAVIILFFTTVLSLVLFAIIFGFLPMNKTTNQKEES", "length": 59, "header": "tr|G3N3X8-1|G3N3X8_BOVIN Isoform 1 of Endoregulin OS=Bos taurus OX=9913 GN=ERLN PE=4 SV=1 CANONICAL=G3N3X8-1" }, "isoforms": [ { "isoform_ac": "G3N3X8-1", "url": "https://www.uniprot.org/uniprotkb/G3N3X8/entry", "sequence": { "sequence": "MDRMLSKYSWKMEFWENPWDQGGLAVIILFFTTVLSLVLFAIIFGFLPMNKTTNQKEES", "length": 59, "header": "tr|G3N3X8-1|G3N3X8_BOVIN Isoform 1 of Endoregulin OS=Bos taurus OX=9913 GN=ERLN PE=4 SV=1 CANONICAL=G3N3X8-1" }, 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"reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [ { "pdb_id": "AF-G3N3X8-F1", "pdb_chain": "global", "start_pos": 1, "end_pos": 59, "overlap": "1.0", "method": "AlphaFold", "type": "alphafold", "resolution": -1.0, "url": "https://data.glygen.org/ln2downloads/pdb/current/AF-G3N3X8-F1.pdb", "url_external": "https://alphafold.ebi.ac.uk/entry/G3N3X8" } ], "lectin_list": [], "domain_list": [], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 50, "end_pos": 52 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ], "tool_support": { "graph_view": "yes" } }, { "uniprot_canonical_ac": "G3X6C8-1", "uniprot_ac": "G3X6C8", "uniprot_id": "G3X6C8_BOVIN", "mass": { "chemical_mass": 89763.0, "monoisotopic_mass": 89763.0 }, "refseq": {}, "gene_names": [ { "name": "FHIP2A", "type": "recommended", "evidence": [ { "id": "G3X6C8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3X6C8" } ] } ], "protein_names": [ { "name": "FHF complex subunit HOOK interacting protein 2A", "type": "synonym", "evidence": [ { "id": "G3X6C8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3X6C8/entry#names_and_taxonomy" } ] } ], "function": [], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Bos taurus", "taxid": 9913, "evidence": [ { "database": "UniProtKB", "id": "G3X6C8", "url": "https://www.uniprot.org/uniprotkb/G3X6C8" } ], "common_name": "Bovine", "glygen_name": "Bovine", "reference_species": "Bos taurus [9913]" } ], "gene": [ { "name": "FHIP2A", "url": "https://www.uniprot.org/uniprotkb/G3X6C8", "locus": { "chromosome": "26", "start_pos": 35312674, "end_pos": 35277610, "strand": "-", "evidence": [ { "database": "Ensembl Gene", "id": "ENSBTAG00000003062", "url": "https://www.ensembl.org/id/ENSBTAG00000003062" } ] } } ], "crossref": [ { "id": "G3X6C8", "url": "https://alphafold.ebi.ac.uk/entry/G3X6C8", "database": "AlphaFoldDB", "categories": [] }, { "id": "ENSBTAG00000003062", "url": "https://bgee.org/?page=gene&gene_id=ENSBTAG00000003062", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "IPR019384", "url": "https://www.ebi.ac.uk/interpro/entry/IPR019384", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR045668", "url": "https://www.ebi.ac.uk/interpro/entry/IPR045668", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR045669", "url": "https://www.ebi.ac.uk/interpro/entry/IPR045669", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "VQTEFFF", "url": "https://omabrowser.org/oma/group/VQTEFFF/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "PTHR21705", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR21705", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR21705:SF10", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR21705:SF10", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF10257", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF10257", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF19311", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF19311", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF19314", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF19314", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "G3X6C8", "url": "https://www.uniprot.org/uniprotkb/G3X6C8", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "G3X6C8-1", "url": "https://www.uniprot.org/uniprotkb/G3X6C8-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MERPRQPQQGRRRRIEELSRSSREKLLQSRDKMFSKFTSILQHAVEALAPSLPLQEDFVYHWKAITHYYIETSDDKAPVTDTNIPSHLEQMLVILVQEENEREFGETGPCMEYLLHHKILETLYTLGKADCPPGMKQQVLVFYTKLLGKIRQPLLPHINVHRPVQKLIRLCGEVLATPTENEEIQFLCIVCAKLKQDPYLVNFFLENKFKSLVSQGGPNAISEDVLKSQDSLSTDTGQSCQAEEPLGASGTEDQPSHQMGDLSTSLENLSVTALPEATVVRPNQDYNLVNSLLNLTRSPDGRIAVKACEGLMLLVSLPEPAAAKCLTQSTCLCELLTDRLASLYKALPQSVDPLDIETVEAVNWGLDSYSHKEDASAFPGKRALISFLSWFDYCDQLIKEAQKTAAVALAKAVHERFFIGVMEPQLMQTSEMGILTSTALLHRIVRQVTSDILLQEMVFFILGEQREPETLAEISRHPLRHRLIEHCDHISDEISIMTLRMFEHLLQKPNEHILYNLVLRNLEERNYTEYKPVCPEDKDVVENGLIAGAVDLEEDPLFTDISPDNTLSNQEWLSSSPPATPDHPKTDGKTEVHKIVNSFLCLVPDEAKSSYHVEGTGYDTYLRDAHRQFRDYCAICLRWEWPGSPKALERCNLEAAFFEGHFLKVLFDRMGRILDQPYDVNLQVTSVLSRLSLFPHPHIHEYLLDPYVNLASGCRSLFSVIVRVVGDLMVRIQRIQDFTPKLLLVRKRLLGLEPEGPVIDHITLLEGVIVLEEFCKELAAIAFVKYHAASTP", "length": 792, "header": "tr|G3X6C8-1|G3X6C8_BOVIN Isoform 1 of FHF complex subunit HOOK interacting protein 2A OS=Bos taurus OX=9913 GN=FHIP2A PE=3 SV=3 CANONICAL=G3X6C8-1" }, "isoforms": [ { "isoform_ac": "G3X6C8-1", "url": "https://www.uniprot.org/uniprotkb/G3X6C8/entry", "sequence": { "sequence": "MERPRQPQQGRRRRIEELSRSSREKLLQSRDKMFSKFTSILQHAVEALAPSLPLQEDFVYHWKAITHYYIETSDDKAPVTDTNIPSHLEQMLVILVQEENEREFGETGPCMEYLLHHKILETLYTLGKADCPPGMKQQVLVFYTKLLGKIRQPLLPHINVHRPVQKLIRLCGEVLATPTENEEIQFLCIVCAKLKQDPYLVNFFLENKFKSLVSQGGPNAISEDVLKSQDSLSTDTGQSCQAEEPLGASGTEDQPSHQMGDLSTSLENLSVTALPEATVVRPNQDYNLVNSLLNLTRSPDGRIAVKACEGLMLLVSLPEPAAAKCLTQSTCLCELLTDRLASLYKALPQSVDPLDIETVEAVNWGLDSYSHKEDASAFPGKRALISFLSWFDYCDQLIKEAQKTAAVALAKAVHERFFIGVMEPQLMQTSEMGILTSTALLHRIVRQVTSDILLQEMVFFILGEQREPETLAEISRHPLRHRLIEHCDHISDEISIMTLRMFEHLLQKPNEHILYNLVLRNLEERNYTEYKPVCPEDKDVVENGLIAGAVDLEEDPLFTDISPDNTLSNQEWLSSSPPATPDHPKTDGKTEVHKIVNSFLCLVPDEAKSSYHVEGTGYDTYLRDAHRQFRDYCAICLRWEWPGSPKALERCNLEAAFFEGHFLKVLFDRMGRILDQPYDVNLQVTSVLSRLSLFPHPHIHEYLLDPYVNLASGCRSLFSVIVRVVGDLMVRIQRIQDFTPKLLLVRKRLLGLEPEGPVIDHITLLEGVIVLEEFCKELAAIAFVKYHAASTP", "length": 792, "header": "tr|G3X6C8-1|G3X6C8_BOVIN Isoform 1 of FHF complex subunit HOOK interacting protein 2A OS=Bos taurus OX=9913 GN=FHIP2A PE=3 SV=3 CANONICAL=G3X6C8-1" }, "locus": { "chromosome": "26", "start_pos": 35311872, "end_pos": 35277693, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000003978.7", "url": "https://www.ensembl.org/id/ENSBTAT00000003978.7" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000003978.7", "url": "https://www.ensembl.org/id/ENSBTAP00000003978.7" } ] } } ], "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "other", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 580, "start_aa": "Thr", "end_pos": 580, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr580", "evidence": [ { "id": "", "database": "GlyGen", "url": "https://data.glygen.org/" } ], "filter_code": "000000000000000010000.00000000001000.0.01000" } ], "phosphorylation": [], "glycation": [], "keywords": [ "glycoprotein", "glycoprotein_predicted" ], "publication": [], "pathway": [], "orthologs": [ { "uniprot_canonical_ac": "B8A6I4-1", "protein_name": "FHF complex subunit HOOK interacting protein 2A isoform 1", "gene_name": "fhip2a", "tax_id": 7955, "organism": "Danio rerio", "sequence": { "sequence": "MFSKFTSILQHAVEALAPSLPLQEDFVYHWKAITHYYIETSDDKAPVTDTNIPSHLEQMLDILTQEERERESGETGPCMEYLLHHKILETLYTLGKADCPPGMKQQVLSFYTKLLGRIRQPLLPHINVHRPVQKLVRLCGEVLAAPTENEEIQFLCTVCAKLKQDPYLVNFFLENKNKRLEAGKEAGTDQVKDDPSSPDTGQNQNQNSSLEDSASQAPSPAEAKPSSVHNTLPNNDNYNLVSSLLNLTKSPDGRIVVKACEGLMLIVSLPEPAAAKCLTENTELSQLLTDRLGQFYRALPQSMDPLDIETVESVNWGLDVYNLKEDAAAFAGKRALISFLSWLDYCDQLIKEAHKSAAAVLARAVRERFFVAVMEPQLMQTSEVGILTSTALLNRIIRQVTSEALLQETIYFLLGEETGPETLAGITQHPLRHRLIEHCDHLSDEISIMTLRLFEHLLQKPCQHILQNLVLRCLEERNYSENKQQEEREEREHMENGQPHDAVDLEEDPLFSDLSPDNRLSSPDWLSCSPPASTEHTKPDGKTEVHKIVNSFLCLVPDEAKSSYQVEGTGYDTYLRDAHRQFRDYCGICQKWDWRSTPKPFEKCNLDSPFFEGHFLKVLFDRMGRILDQPYDVNLQVTSVLSKLSLLPHAHLHEYLLDPYINLAPGCRSLFSVIVRVVGDLMLRTHRIPEFTPKLLLVRKRLLGLEPEGMSVDHVTLLEGVIVLEEFCKELAAIAFVKFHASASTSP", "length": 747 }, "evidence": [ { "id": "G3X6C8", "url": "https://omabrowser.org/oma/group/G3X6C8/", "database": "OMA" } ], "glygen_name": "Zebrafish", "common_name": "Zebrafish" }, { "uniprot_canonical_ac": "D4A3I5-1", "protein_name": "FHF complex subunit HOOK interacting protein 2A", "gene_name": "Fhip2a", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MERSGQPQQGRRRRIEELSRSSREKLLQSRDRMFSKLTSILQHAVEALAPSLPLQEDFVYHWKAITHYYIETSDDKAPVTDTNIPSHLEQMLDILVQEENERESGETGPCMEYLLHHKILETLYTLGKADCPPGMKQQVLVFYTKLLGRIRQPLLPHINVHRPVQKLIRLCGEVLATPTENEEIQFLCIVCAKLKQDPYLVNFFLENKSKSLMSRGALSVISEDDPKGQDPVSGDVSQCHQPQELSGATGVAHAESEEEPPHQMDDLNASLDDLSVTSLPEASAIRPNQDYNLVNSLLNLTRSPDGRIAVKACEGLMLLVSLPEPAAAKCLAQSTCLCELLTGRLTSLYKALPQSVDPLDIETVEAVNWGLDSYSHKEDTSAFPGKRALISFLSWFDYCDQLIKEAQKTAAVALAKAIHERFFVGVMEPQLMQTSEMGILTSTALLHRIVRQVTSDVLLQEMVVFILGEQREPETLSEISRHPLRHRLIEHCDHISDEISIMTLRMFEHLLQKPNEHILYNLVLRNLEERNYTEYKPLCPEDKDVVENGLIAGAVDLEEDPLFTDISPDNTLPNQEWICSPRASPDHPKNDGKTEVHKVVNSFLCLVPDEAKSSYHVEGTGYDTYLRDAHRQFRDYCAVCLRWEWPGAPKPLEKCDLEAAFFEGHFLKVLFDRMGRILDQPYDVNLQVTSVLSRLSLFPHPHTHEYLLDPYVNLASGCRSLFSVIVRVVGDLMVRIQRIQDFTPKLLLVRKRLLGLEPEGPIVDHITLLEGVIVLEEFCKELAAIAFVKFHASSTP", "length": 796 }, "evidence": [ { "id": "G3X6C8", "url": "https://omabrowser.org/oma/group/G3X6C8/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "F1S4V3-1", "protein_name": "FHF complex subunit HOOK interacting protein 2A", "gene_name": "FHIP2A", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MFSKFTSILQHAVEALAPSLPLQEDFVYHWKAITHYYIETSDDKAPVTDTNIPSHLEQMLVILVQEESEREFGETGPCMEYLLHHKILETLYTLGKADCPPGMKQQVLVFYTKLLGKIRQPLLPHINVHRPVQKLIRLCGEVLATPTENEEIQFLCIVCAKLKQDPYLVNFFLENKLKSLASKEAANATSEDIPKGQDSLSADTGQCFRPEELSGASGAESTESEEEPPQQIDDLSAGLDGLSVAALPEATVVRPNQDYNLVNSLLNLTRSPDGRIAVKACEGLMLLVSLPEPAAAKCLTQSTCLCELLTDRLASLYRALPQSVDPLDIETVEAINWGLDSYSHKEDASAFPGKRALISFLSWFDYCDQLIKEAQKTAAVALAKAVRERFFIGVMEPQLMQTSEMGILTSTALLHRIVRQVTSDILLQEMVFFILGEQREPETLAEISRHPLRHRLIEHCDHISDEISIMTLRMFEHLLQKPNEHILYNLVLRNLEERNYTEYKPVCPEDKDVMENGLIAGAVDLEEDPLFTDISPDNTLSNQEWLSSSPPTTPDHPKNDGKTEVHKIVNSFLCLVPDEAKSSYHVEGTGYDTYLRDAHRQFRDYCAICLRWEWPGSPKALEKCNLEAAFFEGHFLKVLFDRMGRILDQPYDVNLQVTSVLSRLSLFPHPHIHEYLLDPYVNLASGCRSLFSVIVRVVGDLMVRIQRIQDFTPKLLLVRKRLLGLEPEGPVIDHITLLEGVIVLEEFCKELAAIAFVKYHAASTP", "length": 765 }, "evidence": [ { "id": "G3X6C8", "url": "https://omabrowser.org/oma/group/G3X6C8/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "Q5W0V3-1", "protein_name": "FHF complex subunit HOOK interacting protein 2A", "gene_name": "FHIP2A", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MFSKFTSILQHAVEALAPSLPLQEDFVYHWKAITHYYIETSDDKAPVTDTNIPSHLEQMLDILVQEENERESGETGPCMEYLLHHKILETLYTLGKADCPPGMKQQVLVFYTKLLGRIRQPLLPHINVHRPVQKLIRLCGEVLATPTENEEIQFLCIVCAKLKQDPYLVNFFLENKMKSLASKGVPNVISEDTLKGQDSLSTDTGQSRQPEELSGATGMEQTELEDEPPHQMDHLSTSLDNLSVTSLPEASVVCPNQDYNLVNSLLNLTRSPDGRIAVKACEGLMLLVSLPEPAAAKCLTQSTCLCELLTDRLASLYKALPQSVDPLDIETVEAINWGLDSYSHKEDASAFPGKRALISFLSWFDYCDQLIKEAQKTAAVALAKAVHERFFIGVMEPQLMQTSEMGILTSTALLHRIVRQVTSDVLLQEMVFFILGEQREPETLAEISRHPLRHRLIEHCDHISDEISIMTLRMFEHLLQKPNEHILYNLVLRNLEERNYTEYKPLCPEDKDVVENGLIAGAVDLEEDPLFTDISPENTLPNQEWLSSSPPATPDHPKNDGKTEVHKIVNSFLCLVPDDAKSSYHVEGTGYDTYLRDAHRQFRDYCAICLRWEWPGSPKALEKCNLEAAFFEGHFLKVLFDRMGRILDQPYDVNLQVTSVLSRLSLFPHPHIHEYLLDPYVNLAPGCRSLFSVIVRVVGDLMLRIQRIQDFTPKLLLVRKRLLGLEPEGPIIDHITLLEGVIVLEEFCKELAAIAFVKYHASSTP", "length": 765 }, "evidence": [ { "id": "G3X6C8", "url": "https://omabrowser.org/oma/group/G3X6C8/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "Q8CDM8-1", "protein_name": "FHF complex subunit HOOK interacting protein 2A", "gene_name": "Fhip2a", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MFSKLTSILQHAVEALAPSLPLQEDFVYHWKAITHYYIETSDDKAPVTDTNIPSHLEQMLDILVQEENERESGETGPCMEYLLHHKILETLYTLGKADCPPGMKQQVLVFYTKLLGRIRQPLLPHINVHRPVQKLIRLCGEVLATPTENEEIQFLCIVCAKLKQDPYLVNFFLENKSKSLVSRGALSVISEDGPKGQDPGSGDVSQCQQPQELSGATGVEPTESEEEPPHQMDDLSASLDDLNVTSLPEASAVRPNQDYNLVNSLLNLTRSPDGRIAVKACEGLMLLVSLPEPAAAKCLAQSTCLCELLTGRLTSLYKALPQSVDPLDIETVEAVNWGLDSYSHKEDASAFPGKRALISFLSWFDYCDQLIKEAQKTAAVALAKAIHERFFVGVMEPQLMQTSEMGILTSTALLHRIVRQVTSDVLLQEMVVFILGEQREPETLSEISRHPLRHRLIEHCDHISDEISIMTLRMFEHLLQKPNEHILYNLVLRNLEERNYTENKPSCPEDKDVVENGLIAGAVDLEEDPLFTDISPDNTLPNQEWICSPRTSPDHPKNDGKTEVHKVVNSFLCLVPDDAKSSYHVEGTGYDTYLRDAHRQFRDYCAICSRWEWPGAPKPLEKCDLEAAFFEGHFLKVLFDRMGRILDQPYDVNLQVTSVLSRLSLFPHPHTHEYLLDPYINLASGCRSLFSVIVRVVGDLMVRIQRIQDFTPKLLLVRKRLLGLEPEGPIVDHITLLEGVIVLEEFCKELAAIAFVKYHASATP", "length": 764 }, "evidence": [ { "id": "G3X6C8", "url": "https://omabrowser.org/oma/group/G3X6C8/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" } ], "go_annotation": {}, "pro_annotation": [], 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"https://www.ebi.ac.uk/interpro/entry/IPR007822", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR012341", "url": "https://www.ebi.ac.uk/interpro/entry/IPR012341", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR020464", "url": "https://www.ebi.ac.uk/interpro/entry/IPR020464", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "G3X6C9", "url": "https://www.orthodb.org/?gene=G3X6C9", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR12736", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR12736", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR12736:SF7", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR12736:SF7", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF05147", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF05147", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "G3X6C9", "url": "https://www.uniprot.org/uniprotkb/G3X6C9", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "G3X6C9-1", "url": "https://www.uniprot.org/uniprotkb/G3X6C9-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MEYPVSPEAEWVAENIAYLSGTLIIAVMLCRLENILISIALQLTVGKLNKIWETACHALPFGHSLFSHFVFDVGSSFPNQGWNPCPLQWKQGVLTAGPKGSAQSHFDSESSFVLVLTGPWFPSALLCCAQTRLTFCNPMDYSPPGSSVHGNLQVLTPAQIKSICQAILDSGKQYAMKKRKPFPLMYSYYGTEYLGAAHGLSSILQMLLSYHEHLKPSDQELVWQSVDFLMEQEQNCNWPPELGEAIERENELVHWCHGAPGIAYLFAKAYLVSKKPQYLDTCIRCGELTWQKGLLKKGPGICHGVAGSAYVFLLLYRLTGNSKYIYRAQRFAEFLFTEEFKAGSRVLESIYSLYEGFSGTVCFLIDLLQPNQAEFPLFSVFV", "length": 382, "header": "tr|G3X6C9-1|G3X6C9_BOVIN Isoform 1 of LanC-like protein 3 OS=Bos taurus OX=9913 GN=LANCL3 PE=3 SV=2 CANONICAL=G3X6C9-1" }, "isoforms": [ { "isoform_ac": "G3X6C9-1", "url": "https://www.uniprot.org/uniprotkb/G3X6C9/entry", "sequence": { "sequence": 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"G3X6Y2-1", "uniprot_ac": "G3X6Y2", "uniprot_id": "G3X6Y2_BOVIN", "mass": { "chemical_mass": 35443.0, "monoisotopic_mass": 35443.0 }, "refseq": {}, "gene_names": [ { "name": "CXHXorf38", "type": "recommended", "evidence": [ { "id": "G3X6Y2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3X6Y2" } ] } ], "protein_names": [ { "name": "Chromosome X CXorf38 homolog", "type": "synonym", "evidence": [ { "id": "G3X6Y2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3X6Y2/entry#names_and_taxonomy" } ] } ], "function": [], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Bos taurus", "taxid": 9913, "evidence": [ { "database": "UniProtKB", "id": "G3X6Y2", "url": "https://www.uniprot.org/uniprotkb/G3X6Y2" } ], "common_name": "Bovine", "glygen_name": "Bovine", "reference_species": "Bos taurus [9913]" } ], "gene": [ { "name": "CXHXorf38", "url": "https://www.uniprot.org/uniprotkb/G3X6Y2", "locus": { "chromosome": "X", "start_pos": 102865828, "end_pos": 102845347, "strand": "-", "evidence": [ { "database": "Ensembl Gene", "id": "ENSBTAG00000011788", "url": "https://www.ensembl.org/id/ENSBTAG00000011788" } ] } } ], "crossref": [ { "id": "G3X6Y2", "url": "https://alphafold.ebi.ac.uk/entry/G3X6Y2", "database": "AlphaFoldDB", "categories": [] }, { "id": "ENSBTAG00000011788", "url": "https://bgee.org/?page=gene&gene_id=ENSBTAG00000011788", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "IPR027897", "url": "https://www.ebi.ac.uk/interpro/entry/IPR027897", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "G3X6Y2", "url": "https://www.orthodb.org/?gene=G3X6Y2", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR35083", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR35083", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR35083:SF1", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR35083:SF1", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF15112", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF15112", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "G3X6Y2", "url": "https://www.uniprot.org/uniprotkb/G3X6Y2", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "G3X6Y2-1", "url": "https://www.uniprot.org/uniprotkb/G3X6Y2-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MVLSELAVRLNCAEYKNWVKAGHCLLLLRGCLQGFVGREMLAFHSRLLAAAPGLGPRAACSSGSRCSPRARQPQCQVCAEWKREILKHHTNRNGDVHWGNCRPAFWPVDAWEVAKAFMPRGLADKTGPEECDAVALLNLINSCDHFVVDRRKVTEVIKCRNEIMHSSEMKVSSVWLRDFQMKIQNFLNEFKNIPEIVAVYSQIEQLLTSDWAVYIPEEDQRDGCDKGVYLSESQVNEIEMELLKEKLQELYLQVKEQEVLPEEILNQLEVVKEFLRNNEDLRNGLTEDIQKLDSLRQQHLKPDSKEPGV", "length": 309, "header": "tr|G3X6Y2-1|G3X6Y2_BOVIN Isoform 1 of Chromosome X CXorf38 homolog OS=Bos taurus OX=9913 GN=CXHXorf38 PE=4 SV=3 CANONICAL=G3X6Y2-1" }, "isoforms": [ { "isoform_ac": "G3X6Y2-1", "url": "https://www.uniprot.org/uniprotkb/G3X6Y2/entry", "sequence": { "sequence": "MVLSELAVRLNCAEYKNWVKAGHCLLLLRGCLQGFVGREMLAFHSRLLAAAPGLGPRAACSSGSRCSPRARQPQCQVCAEWKREILKHHTNRNGDVHWGNCRPAFWPVDAWEVAKAFMPRGLADKTGPEECDAVALLNLINSCDHFVVDRRKVTEVIKCRNEIMHSSEMKVSSVWLRDFQMKIQNFLNEFKNIPEIVAVYSQIEQLLTSDWAVYIPEEDQRDGCDKGVYLSESQVNEIEMELLKEKLQELYLQVKEQEVLPEEILNQLEVVKEFLRNNEDLRNGLTEDIQKLDSLRQQHLKPDSKEPGV", "length": 309, "header": "tr|G3X6Y2-1|G3X6Y2_BOVIN Isoform 1 of Chromosome X CXorf38 homolog OS=Bos taurus OX=9913 GN=CXHXorf38 PE=4 SV=3 CANONICAL=G3X6Y2-1" }, "locus": { "chromosome": "X", "start_pos": 102865120, "end_pos": 102845418, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000015650.8", "url": "https://www.ensembl.org/id/ENSBTAT00000015650.8" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000015650.7", "url": "https://www.ensembl.org/id/ENSBTAP00000015650.7" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [], "orthologs": [], "go_annotation": {}, "pro_annotation": [], "site_annotation": [], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [ { "pdb_id": "AF-G3X6Y2-F1", "pdb_chain": "global", "start_pos": 1, "end_pos": 309, "overlap": "1.0", "method": "AlphaFold", "type": "alphafold", "resolution": -1.0, "url": "https://data.glygen.org/ln2downloads/pdb/current/AF-G3X6Y2-F1.pdb", "url_external": "https://alphafold.ebi.ac.uk/entry/G3X6Y2" } ], "lectin_list": [], "domain_list": [], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ], "tool_support": { "graph_view": "yes" } }, { "uniprot_canonical_ac": "G3X6Y5-1", "uniprot_ac": "G3X6Y5", "uniprot_id": "G3X6Y5_BOVIN", "mass": { "chemical_mass": 104472.0, "monoisotopic_mass": 104472.0 }, "refseq": {}, "gene_names": [ { "name": "PCDH20", "type": "recommended", "evidence": [ { "id": "G3X6Y5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3X6Y5" } ] } ], "protein_names": [ { "name": "Protocadherin-20", "type": "recommended", "evidence": [ { "id": "G3X6Y5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3X6Y5/entry#names_and_taxonomy" } ] } ], "function": [ { "annotation": "Potential calcium-dependent cell-adhesion protein.", "evidence": [ { "database": "UniProtKB", "id": "G3X6Y5", "url": "https://www.uniprot.org/uniprotkb/G3X6Y5#function" }, { "database": "UniProtKB", "id": "ARBA00037723", "url": "https://www.uniprot.org/uniprotkb/ARBA00037723#function" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Bos taurus", "taxid": 9913, "evidence": [ { "database": "UniProtKB", "id": "G3X6Y5", "url": "https://www.uniprot.org/uniprotkb/G3X6Y5" } ], "common_name": "Bovine", "glygen_name": "Bovine", "reference_species": "Bos taurus [9913]" } ], "gene": [ { "name": "PCDH20", "url": "https://www.uniprot.org/uniprotkb/G3X6Y5", "locus": { "chromosome": "12", "start_pos": 480875, "end_pos": 476919, "strand": "-", "evidence": [ { "database": "Ensembl Gene", "id": "ENSBTAG00000011862", "url": "https://www.ensembl.org/id/ENSBTAG00000011862" } ] } } ], "crossref": [ { "id": "G3X6Y5", "url": "https://alphafold.ebi.ac.uk/entry/G3X6Y5", "database": "AlphaFoldDB", "categories": [] }, { "id": "ENSBTAG00000011862", "url": "https://bgee.org/?page=gene&gene_id=ENSBTAG00000011862", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "cd11304", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd11304", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "IPR002126", "url": "https://www.ebi.ac.uk/interpro/entry/IPR002126", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR015919", "url": "https://www.ebi.ac.uk/interpro/entry/IPR015919", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR020894", "url": "https://www.ebi.ac.uk/interpro/entry/IPR020894", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR050174", "url": "https://www.ebi.ac.uk/interpro/entry/IPR050174", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IEHPAMD", "url": "https://omabrowser.org/oma/group/IEHPAMD/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "PTHR24028", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR24028", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR24028:SF260", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR24028:SF260", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00028", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00028", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "G3X6Y5", "url": "https://www.uniprot.org/uniprotkb/G3X6Y5", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "G3X6Y5-1", "url": "https://www.uniprot.org/uniprotkb/G3X6Y5-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MRGGGDACGSQAGAVSWSRATWRPRPDMGSLSRPSSSASHGNLPHLLLFFLFVGPFNCLASYSRATEILYSLNEGLPAGVLIGSLAEDLRLLPGAGGQDLLSQSPQHSVAERNPPLSFSLASQGLSGQYVTLDNRSGELHTSAQEIDREALCLEGGGGIAWGSSISISSSPSADSCLLLLDVLVLPQEYFRFVKVKIAIRDINDNAPRFPISQISVWVPENAPVNTRLAIEHPAVDPDMGTNGVQTYRLLDYHRMFTLDVEENENGERTPYLIVMGLLDRETQDQYVSVIIAEDGGSPPLIGSATLTIGISDINDNCPLFTDSQINITVYGNATVGTPIAAVQAVDRDLGNNAQITYSYSQKVPQASKDLFHLNENTGVIKLFSKIGGSVLQTHKLTILANGPGCIPAVITALVTIIKVIFRPPEIVPRYIANQIDGIIYLKELEPVNTPIAFFTIRDPEGKYKVNCYLDSEGPFRLLPYKPYSNEYLLETTKPMDYELQQFYEIAIVAWNSEGFQVKKMIKVQLLDDNDNAPVFLQPLVELTIEENNAPNAFLTKLDATDADSGERGQVSYFLGPDAPSYFSLDSVTGILTVSTQLDREEKEKYRYTVRAVDSGKPPQESVATVVITVLDKNDNSPRFINKDFSFFVPENFPGYGEIGVISVTDADTGQNGWVALSVVNQSDIFVIDTGKGLLRAKVSLDREQQSSYTLWVEAVDGGTPPLSSTAKITILLLDINDNPPLVLFPQSNMSYLLVLPSTLPGSLVTEVYAVDKDTGMNAVIAYSIIGRRGPRPESFRIDPKTGNITLEEALLQTDYGLHRLLVKVSDHGYPEPLHSTVMVNLFVNDTVSNESYIENLLRKEPEISIEEKEPQISIEPTHRKAESVSCMPTLVALSVISLSSITFLTGMGICICLRREKKHHREDENLEVQTPLKGKIDLHMRERKPMDISNI", "length": 951, "header": "tr|G3X6Y5-1|G3X6Y5_BOVIN Isoform 1 of Protocadherin-20 OS=Bos taurus OX=9913 GN=PCDH20 PE=4 SV=2 CANONICAL=G3X6Y5-1" }, "isoforms": [ { "isoform_ac": "G3X6Y5-1", "url": "https://www.uniprot.org/uniprotkb/G3X6Y5/entry", "sequence": { "sequence": "MRGGGDACGSQAGAVSWSRATWRPRPDMGSLSRPSSSASHGNLPHLLLFFLFVGPFNCLASYSRATEILYSLNEGLPAGVLIGSLAEDLRLLPGAGGQDLLSQSPQHSVAERNPPLSFSLASQGLSGQYVTLDNRSGELHTSAQEIDREALCLEGGGGIAWGSSISISSSPSADSCLLLLDVLVLPQEYFRFVKVKIAIRDINDNAPRFPISQISVWVPENAPVNTRLAIEHPAVDPDMGTNGVQTYRLLDYHRMFTLDVEENENGERTPYLIVMGLLDRETQDQYVSVIIAEDGGSPPLIGSATLTIGISDINDNCPLFTDSQINITVYGNATVGTPIAAVQAVDRDLGNNAQITYSYSQKVPQASKDLFHLNENTGVIKLFSKIGGSVLQTHKLTILANGPGCIPAVITALVTIIKVIFRPPEIVPRYIANQIDGIIYLKELEPVNTPIAFFTIRDPEGKYKVNCYLDSEGPFRLLPYKPYSNEYLLETTKPMDYELQQFYEIAIVAWNSEGFQVKKMIKVQLLDDNDNAPVFLQPLVELTIEENNAPNAFLTKLDATDADSGERGQVSYFLGPDAPSYFSLDSVTGILTVSTQLDREEKEKYRYTVRAVDSGKPPQESVATVVITVLDKNDNSPRFINKDFSFFVPENFPGYGEIGVISVTDADTGQNGWVALSVVNQSDIFVIDTGKGLLRAKVSLDREQQSSYTLWVEAVDGGTPPLSSTAKITILLLDINDNPPLVLFPQSNMSYLLVLPSTLPGSLVTEVYAVDKDTGMNAVIAYSIIGRRGPRPESFRIDPKTGNITLEEALLQTDYGLHRLLVKVSDHGYPEPLHSTVMVNLFVNDTVSNESYIENLLRKEPEISIEEKEPQISIEPTHRKAESVSCMPTLVALSVISLSSITFLTGMGICICLRREKKHHREDENLEVQTPLKGKIDLHMRERKPMDISNI", "length": 951, "header": "tr|G3X6Y5-1|G3X6Y5_BOVIN Isoform 1 of Protocadherin-20 OS=Bos taurus OX=9913 GN=PCDH20 PE=4 SV=2 CANONICAL=G3X6Y5-1" }, "locus": { "chromosome": "12", "start_pos": 480872, "end_pos": 477004, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000015745.7", "url": "https://www.ensembl.org/id/ENSBTAT00000015745.7" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000015745.5", "url": "https://www.ensembl.org/id/ENSBTAP00000015745.5" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [], "orthologs": [ { "uniprot_canonical_ac": "A0A287BJ35-1", "protein_name": "Protocadherin-20", "gene_name": "PCDH20", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MRGGGDVRSSRALAVSWSPATWHPRLDMGHPSRPRSSTSHRNLPHLLLFFLFVGPFNCLASYSRATELLYSLNEGLPAGVLIGSLAEDLRLVPRAGKQDPKSQLPEHSGAAEQNLPLSFSLASQGLSGQYVTLDNRSGELHTSAQEIDREALCLEGGGGAAWGGSISISSSPSADSCLLLLDVLVLPQEYFRFVKVKIAIRDVNDNAPQFPVSQISVWVPENAPVNTRLAIEHPATDPDIGTNGVQTYRLLDYHRMFTLDVEENENGERTPYLIVMGLLDRETQDQYVSIIIAEDGGSPPLLGSATLTIGISDINDNCPLFTDSQINVTVYGNATVGTPIAAVQAVDRDLGNNAEITYSYSQKVPQASKDLFHLDETTGVIKLFSKIGGSVLQTHKLTILANGPGCIPAVITALVTIIKVIFRPPEIVPRYIANEIDGIVYLKELEPVNTPIAFFTIRDPEGKYKVNCYLDGEGPFRLSPYKPYSNEYLLETTKTMDYELQQFYEIAVVAWNSEGFHVKKTIKVQLLDDNDNAPIFLQPLVELTIEENNAPNAFLAKLDATDADSGERGQVSYFLGPDAPAYFSLDSVTGILTVSTQLDREEKEKYRYTVRAVDSGKPPKESVATVAITVLDKNDNSPRFINKDFSFFVPENFPGYGEIGVISVTDADAGQNGWVALSVVNQSDIFVIDTGKGMLRAKVSLDREQQSSYTLWVEAVDGGEPPLSSTAKITILLLDINDNPPLVLFPQSNMSYLLVLPSTLPGSPVTEVYAVDKDTGMNAVIAYSIIGRRGPRPESFRIDPKTGNITLEEALLQTDYGLHRLLVKVSDHGYPEPLHSTVMVNLFVNDTVSNESYIESLLKKEPEINIEEKEPQISIEPTHRRFESVSCMPTLVALSVISLGSITLVTGMGIYICLRRGKKHHREEENLEVQIPLKGKIDLHMRERKPMDISNI", "length": 952 }, "evidence": [ { "id": "G3X6Y5", "url": "https://omabrowser.org/oma/group/G3X6Y5/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "D4ADD1-1", "protein_name": "Protocadherin-20", "gene_name": "Pcdh20", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MRGQGNARSSLVQAVSLRPATWHPCLDMGHLHRPSSRTSHRNLPHVVLLFLFVGPFNCLASYSRATELLYSLNEGLPAGVLIGSLAEDLRLLPRASGRQSQQLLHPERTAAEGNPPLSFSLASGGLSGQYVTLDNRSGELHTSAQEIDREALCLDGGGGAAWGGSTSIASSPSSDSCLLLLDVLVLPQEYFRFVKVKIAIRDINDNAPQFPISEISVWVPENSPVNTRLAIEHPAVDPDVGINGVQTYRLLDYHGMFTLDVEENENGERTPYLIVMGALDRETQDQYVSIIIAEDGGSPPLLGSATLTIGISDINDNCPLFIDSQINVTVYGNATVGTPVTTVQAVDRDLGTNAQITYSYSQKVPQESKELFHLDEVTGVVKLSSKIGGNVLQTHKLTILANGPGCIPAVITALVSIIKVVFRPPEIVPRYIANEMDGVVYLKELEPVNTPIAFFTIRDPEGKYKINCYLEGEGPFRLAPYKPYNNEYLLETTKPMDYELQPFYEIAVVAWNSEGFHDKRIIKVQLLDDNDNAPVFLQPLIELTIEENNAPNAFLTKLYATDADSGEMGRVSYFLGPDAPSYFSLDSVTGILTVSTQLDREEKEKYRYTVRAVDCGKPPRESVATVALTVLDKNDNSPRFINKDFSFFVPENFPGYGEIGVISVTDADAGRNGWVALSVMNQSDIFVIDTGKGMLRAKVSLDREQQSSYTLWVEAVDGGEPALSSTTKITILLLDINDNPPLVLFPQSNMSYLLVLPSTLPGSPVTEVYAVDKDTGMNAVIAYSIIGRRGPRPESFRIDPKTGNITLEEALLQTDYGLHRLLVKVSDHGYPEPLHSTVMVNLFVNDTVSNESYIESLLRKEPEINIEEKEPQISIKPTHRKVESMSCMPTLVALSVISLASITLVTGMGIYICLRKGKKHHREDDNLEVQIPLKGRIDLCMRERKPMDISNI", "length": 952 }, "evidence": [ { "id": "G3X6Y5", "url": "https://omabrowser.org/oma/group/G3X6Y5/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "E7F9B5-1", "protein_name": "Protocadherin-20", "gene_name": "pcdh20", "tax_id": 7955, "organism": "Danio rerio", "sequence": { "sequence": "MWNTKRRICLHSTGELWGLFILLLYSIPFSCSSNFSHLIYKIKEGLPKGTLIGAISADLTLDLSVNPSRSFSLEQMTTSEHYVNLNSTTGELFTSAIEIDRESLCAESHEGQGCAIFLDVLILPQQYFQLVKIKIIIEDINDNSPHFPMDEIRLSVPENAPVNARFAVEQSAVDPDIGIHSVQTYWLNNDYGVFTLDVEENEGGELTPFLILTESLDREARAEYVTEIIAEDGGSPPRFGNATLRIIISDVNDNCPKFRESQVKVTLYGNATKGMQLARLQAYDPDEGANALITYTFSERVSQESKSLFHLDTTTGVLKLAGKINNNSAKLYKINILANGAGCIPDVAMVSVHVIKQLSGPPTVVPRYIAFEKDGVVSLSESEPPFSPIAFFTIKNTEAQQKLECFLESAGPFRIVPYQGLKNEYLLETTDVLDYELQQDYEIVIVVRNSHGLAVNTVVKVHVLDVNDNAPVFKQSFVEIAVEENNPPNTFLAQLQASDADSESRGQVYYQLGADAPTIFNIDSYTGVLTVSTSLDREEKETYRFMVRALDRGTPKKESIATVIITVQDRNDNSPRFINKDFTFFVPENFPGFGEIGVLTVTDADAGENGWVALSILNGSDIFVIDTGRGALRAKTPLDREQQGTYYVWIEAIDGGEPALSCVTMVTVLLLDVNDNPPTVLFPQSNQSFMLVLPSTVPGTSITEVYAVDRDTGMNAVIAYSIIKRTDGEPGSFDIDPYTGNITLRKALNSRGLYSLWVKVRDHGQPELYSTVLVNLFVNETVSNETLIQSLLPRVVDLDHGEAPPVKEGREGERVPNMCNEYKVILLALTATCMGLFLTVVSLVTYICCKKRKTKKKRQGTETLKLNHEMVEKNLLEISNI", "length": 881 }, "evidence": [ { "id": "G3X6Y5", "url": "https://omabrowser.org/oma/group/G3X6Y5/", "database": "OMA" } ], "glygen_name": "Zebrafish", "common_name": "Zebrafish" }, { "uniprot_canonical_ac": "F1NY34-1", "protein_name": "Protocadherin-20", "gene_name": "PCDH20", "tax_id": 9031, "organism": "Gallus gallus", "sequence": { "sequence": "MGWRGAKDVFHMERGVGEAVFEGLLGGRHLLLFLLFVGPFNCFASYSRATELFYSLNEGLPAGVLIGSLARDLRLPTAGGQRPAAPQPPLSFTLASRGLGGQYVHLDNRSGELHTSALEIDREALCMESGGSTVPGEGDTVSLSSSSSSPDSCLLLLDVLVLPQEYFRLVKVKIAIRDVNDNAPRFPVPHIHLSVPENAPVNTRLAIEHPALDPDVGTNGVQTYRLRDNYGVFTLDVEENESGERTPYLIVMGALDRETREEYVTVIIAEDGGTPPLVGSATLTIGISDINDNCPQFSDTQLNITLYGNSSLGTHVATVHAVDLDLGSNAQITYSYSQKVPQPSRDLFHLDESTGVITLSSKVDGNTPRLHRLIILGNGPGCIPAVITVLVTIIKVMMRPPEVVPRFIANEMEGVVYLKELEPINTPIAFFTIKDPDEKYKVNCYLDGDGPFRLSPYKPYNNEYLLETTKPLDYETQQLYEISVVAWNSEGFNVNKVIKIQVLDDNDNSPIFSQQLIELSIEENNVPNAFLTKLHATDADSGERGEVSYFLGPDAPSYFSLDKTTGVLTVATQLDREEKEKYRYTVKAVDSGFPPRESIATVTITVLDKNDNSPRFINKDFSFFVPENFPGFGEIGVISVTDADAGQNGWVALSVLNGSDIFVIDTGKGVLRAKVSLDREQQSSYVLWIEAVDGGDPALSSTAKITILLLDINDNPPLVLFPQSNMSYLLVLPSTLPGSPITEVYAVDKDTGMNAVIAYSIIGRRGPRPESFRIDPKTGNITLEESLMQNDYGLYRLLVKVSDHGYPEPLHSTVMVNLFVNDTVSNESYIESLLRKEPDINIEEKQPQISVEPTHKKMESASCMPTLVALSIISLGSITLVTGMGIYICLRKGKKHHRADENLEVQIPLNGRINLHMLEKKPVEISNI", "length": 928 }, "evidence": [ { "id": "G3X6Y5", "url": "https://omabrowser.org/oma/group/G3X6Y5/", "database": "OMA" } ], "glygen_name": "Chicken", "common_name": "Chicken" }, { "uniprot_canonical_ac": "Q8BIZ0-1", "protein_name": "Protocadherin-20", "gene_name": "Pcdh20", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MRGRGNARSLLVQAVSLRPATWHPCLDMGHLHRPSSRTSHRNLPHVFLLFLFVGPFNCLASYSRATELLYSLNEGLPAGVLIGSLAEDLRLLPRASGRQNQQLLHPERTASEGNPPLSFSLASGGLSGQYVTLNNRSGELHTSAQEIDREALCLDGGGGAAWAGSTSIASSPSSDSCLLLLDVLVLPQEYFRFVKVKIAIRDINDNAPQFPISEISVWVPENSPVNTRLAIEHPAVDPDVGINGVQTYRLLDYHGMFTLDVEENENGERTPYLIVMGALDRETQDQYVSIIIAEDGGSPPLLGSATLTIGISDINDNCPLFIDSQINVTVYGNATVGTPVATVQAVDRDLGTNAQITYSYSQKVPQETKDLFHLDEVTGVIKLSSKIGGSVLQTHKLTILANGPGCIPAVITALVSIIKVVFRPPEIVPRYIANEVDGVVYLKELEPVNTPIAFFTIRDPEGKYKINCFLDGEGPFRLAPYKPYNNEYLLETTKPMDYEVQSFYEIAVVAWNSEGFHVKRIIKVQLLDDNDNAPVFLQPLIELTIEENNAPNAFLTKLYATDADSGEMGRVSYFLGPDAPSYFSLDSVTGILTVSTQLDREEKEKYRYTVRAVDCGTPPRESVATVALTVLDKNDNSPRFINKDFSFFVPENFPGYGEIGVISVTDADAGRNGWVALSVMNQSDIFVIDTGKGMLRAKVSLDREQQSSYTLWVEAVDGGEPALSSTTKITILLLDINDNPPLVLFPQSNMSYLLVLPSTLPGSPVTEVYAVDKDTGMNAVIAYSIIGRRGPRPESFRIDPKTGNITLEEALLQTDYGLHRLLVKVSDHGYPEPLHSTVMVNLFVNDTVSNESYIESLLRKEPEINIEEKEPQISIEPTHRKVESMSCMPTLVALSVISLGSITLVTGMGIYICLRKGKKHHREDDNLEVQIPLKGKIDLCMRERKPVDISNI", "length": 952 }, "evidence": [ { "id": "G3X6Y5", "url": "https://omabrowser.org/oma/group/G3X6Y5/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q8N6Y1-1", "protein_name": "Protocadherin-20", "gene_name": "PCDH20", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MRGRGNARSSQALGVSWCPATWHPRLDMGRLHRPRSSTSYRNLPHLFLFFLFVGPFSCLGSYSRATELLYSLNEGLPAGVLIGSLAEDLRLLPRSAGRPDPQSQLPERTGAEWNPPLSFSLASRGLSGQYVTLDNRSGELHTSAQEIDREALCVEGGGGTAWSGSVSISSSPSDSCLLLLDVLVLPQEYFRFVKVKIAIRDINDNAPQFPVSQISVWVPENAPVNTRLAIEHPAVDPDVGINGVQTYRLLDYHGMFTLDVEENENGERTPYLIVMGALDRETQDQYVSIIIAEDGGSPPLLGSATLTIGISDINDNCPLFTDSQINVTVYGNATVGTPIAAVQAVDKDLGTNAQITYSYSQKVPQASKDLFHLDENTGVIKLFSKIGGSVLESHKLTILANGPGCIPAVITALVSIIKVIFRPPEIVPRYIANEIDGVVYLKELEPVNTPIAFFTIRDPEGKYKVNCYLDGEGPFRLSPYKPYNNEYLLETTKPMDYELQQFYEVAVVAWNSEGFHVKRVIKVQLLDDNDNAPIFLQPLIELTIEENNSPNAFLTKLYATDADSEERGQVSYFLGPDAPSYFSLDSVTGILTVSTQLDREEKEKYRYTVRAVDCGKPPRESVATVALTVLDKNDNSPRFINKDFSFFVPENFPGYGEIGVISVTDADAGRNGWVALSVVNQSDIFVIDTGKGMLRAKVSLDREQQSSYTLWVEAVDGGEPALSSTAKITILLLDINDNPPLVLFPQSNMSYLLVLPSTLPGSPVTEVYAVDKDTGMNAVIAYSIIGRRGPRPESFRIDPKTGNITLEEALLQTDYGLHRLLVKVSDHGYPEPLHSTVMVNLFVNDTVSNESYIESLLRKEPEINIEEKEPQISIEPTHRKVESVSCMPTLVALSVISLGSITLVTGMGIYICLRKGEKHPREDENLEVQIPLKGKIDLHMRERKPMDISNI", "length": 951 }, "evidence": [ { "id": "G3X6Y5", "url": "https://omabrowser.org/oma/group/G3X6Y5/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" } ], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 1, "go_terms": [ { "name": "plasma membrane", "id": "GO:0005886", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005886", "evidence": [ { "database": "UniProtKB", "id": "G3X6Y5", "url": "https://www.uniprot.org/uniprotkb/G3X6Y5" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 2, "go_terms": [ { "name": "cell adhesion", "id": "GO:0007155", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007155", "evidence": [ { "database": "UniProtKB", "id": "G3X6Y5", "url": "https://www.uniprot.org/uniprotkb/G3X6Y5" } ], "pmid": "" }, { "name": "homophilic cell adhesion via plasma membrane adhesion molecules", "id": "GO:0007156", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007156", "evidence": [ { "database": "UniProtKB", "id": "G3X6Y5", "url": "https://www.uniprot.org/uniprotkb/G3X6Y5" } ], "pmid": "" } ] }, { "name": "Molecular Function", "total": 2, "go_terms": [ { "name": "calcium ion binding", "id": "GO:0005509", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005509", "evidence": [ { "database": "UniProtKB", "id": "G3X6Y5", "url": "https://www.uniprot.org/uniprotkb/G3X6Y5" } ], "pmid": "" }, { "name": "cell adhesion molecule binding", "id": "GO:0050839", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0050839", "evidence": [ { "database": "UniProtKB", "id": "G3X6Y5", "url": "https://www.uniprot.org/uniprotkb/G3X6Y5" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 134, "end_pos": 136, "annotation": "n_glycosylation_sequon" }, { "start_pos": 326, "end_pos": 328, "annotation": "n_glycosylation_sequon" }, { "start_pos": 332, "end_pos": 334, "annotation": "n_glycosylation_sequon" }, { "start_pos": 680, "end_pos": 682, "annotation": "n_glycosylation_sequon" }, { "start_pos": 748, "end_pos": 750, "annotation": "n_glycosylation_sequon" }, { "start_pos": 803, "end_pos": 805, "annotation": "n_glycosylation_sequon" }, { "start_pos": 844, "end_pos": 846, "annotation": "n_glycosylation_sequon" }, { "start_pos": 849, "end_pos": 851, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [ { "pdb_id": "AF-G3X6Y5-F1", "pdb_chain": "global", "start_pos": 1, "end_pos": 951, "overlap": "1.0", "method": "AlphaFold", "type": "alphafold", "resolution": -1.0, "url": "https://data.glygen.org/ln2downloads/pdb/current/AF-G3X6Y5-F1.pdb", "url_external": "https://alphafold.ebi.ac.uk/entry/G3X6Y5" } ], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "G3X6Y5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3X6Y5" }, { "id": "PS50268", "database": "PROSITE", "url": "https://prosite.expasy.org/PS50268" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "Cadherin", "eco_id": "ECO_0000259", "start_pos": 64, "end_pos": 209, "start_aa": "Arg", "end_aa": "Phe", "glycosite_overlap": [] } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "homologset.oma", "label": "OMA Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 134, "end_pos": 136 }, { "start_pos": 326, "end_pos": 328 }, { "start_pos": 332, "end_pos": 334 }, { "start_pos": 680, "end_pos": 682 }, { "start_pos": 748, "end_pos": 750 }, { "start_pos": 803, "end_pos": 805 }, { "start_pos": 844, "end_pos": 846 }, { "start_pos": 849, "end_pos": 851 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ], "tool_support": { "graph_view": "yes" } }, { "uniprot_canonical_ac": "G3X712-1", "uniprot_ac": "G3X712", "uniprot_id": "G3X712_BOVIN", "mass": { "chemical_mass": 16993.0, "monoisotopic_mass": 16993.0 }, "refseq": {}, "gene_names": [], "protein_names": [ { "name": "Ig-like domain-containing protein", "type": "recommended", "evidence": [ { "id": "G3X712", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3X712/entry#names_and_taxonomy" } ] } ], "function": [], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Bos taurus", "taxid": 9913, "evidence": [ { "database": "UniProtKB", "id": "G3X712", "url": "https://www.uniprot.org/uniprotkb/G3X712" } ], "common_name": "Bovine", "glygen_name": "Bovine", "reference_species": "Bos taurus [9913]" } ], "gene": [ { "name": "", "url": "https://www.uniprot.org/uniprotkb/G3X712", "locus": {} } ], "crossref": [ { "id": "G3X712", "url": "https://alphafold.ebi.ac.uk/entry/G3X712", "database": "AlphaFoldDB", "categories": [] }, { "id": "ENSBTAG00000050781", "url": "https://bgee.org/?page=gene&gene_id=ENSBTAG00000050781", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "IPR003599", "url": "https://www.ebi.ac.uk/interpro/entry/IPR003599", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR007110", "url": "https://www.ebi.ac.uk/interpro/entry/IPR007110", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR013106", "url": "https://www.ebi.ac.uk/interpro/entry/IPR013106", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR013783", "url": "https://www.ebi.ac.uk/interpro/entry/IPR013783", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR036179", "url": "https://www.ebi.ac.uk/interpro/entry/IPR036179", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR051896", "url": "https://www.ebi.ac.uk/interpro/entry/IPR051896", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "LERIYWS", "url": "https://omabrowser.org/oma/group/LERIYWS/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "PTHR19339", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR19339", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR19339:SF2", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR19339:SF2", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF07686", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF07686", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "G3X712", "url": "https://www.uniprot.org/uniprotkb/G3X712", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "G3X712-1", "url": "https://www.uniprot.org/uniprotkb/G3X712-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MKRLVDTVLGLLFAQVCCVRGMDVAQSPPALSLQEGASSTLRCNFSTFADSVQWYLQNPRGRLIHLFYVPSGTKRDGRLNATTVPTERRSSLHISSSQTTDSGTYFCAVQHSAPQAPAASTQTLRGAQPLLQPQSHREATTGHLQCLTLLTYISTV", "length": 156, "header": "tr|G3X712-1|G3X712_BOVIN Isoform 1 of Ig-like domain-containing protein OS=Bos taurus OX=9913 GN= PE=4 SV=2 CANONICAL=G3X712-1" }, "isoforms": [ { "isoform_ac": "G3X712-1", "url": "https://www.uniprot.org/uniprotkb/G3X712/entry", "sequence": { "sequence": "MKRLVDTVLGLLFAQVCCVRGMDVAQSPPALSLQEGASSTLRCNFSTFADSVQWYLQNPRGRLIHLFYVPSGTKRDGRLNATTVPTERRSSLHISSSQTTDSGTYFCAVQHSAPQAPAASTQTLRGAQPLLQPQSHREATTGHLQCLTLLTYISTV", "length": 156, "header": "tr|G3X712-1|G3X712_BOVIN Isoform 1 of Ig-like domain-containing protein OS=Bos taurus OX=9913 GN= PE=4 SV=2 CANONICAL=G3X712-1" }, "locus": { "chromosome": "10", "start_pos": 25262726, "end_pos": 25262070, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000017034.5", "url": "https://www.ensembl.org/id/ENSBTAT00000017034.5" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000017034.5", "url": "https://www.ensembl.org/id/ENSBTAP00000017034.5" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [], "orthologs": [ { "uniprot_canonical_ac": "A0A075B618-1", "protein_name": "T cell receptor alpha variable 13D-4", "gene_name": "Trav13d-4", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "GQQVQQSPASLVLQEGENAELQCNFSSTATRLQWFYQRPGGSLVSLLYNPSGTKHTGRLTSTTVTKERRSSLHISSSQTTDSGTYFCA", "length": 88 }, "evidence": [ { "id": "G3X712", "url": "https://omabrowser.org/oma/group/G3X712/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" } ], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 1, "go_terms": [ { "name": "T cell receptor complex", "id": "GO:0042101", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0042101", "evidence": [ { "database": "UniProtKB", "id": "G3X712", "url": "https://www.uniprot.org/uniprotkb/G3X712" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 44, "end_pos": 46, "annotation": "n_glycosylation_sequon" }, { "start_pos": 80, "end_pos": 82, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [ { "pdb_id": "AF-G3X712-F1", "pdb_chain": "global", "start_pos": 1, "end_pos": 156, "overlap": "1.0", "method": "AlphaFold", "type": "alphafold", "resolution": -1.0, "url": "https://data.glygen.org/ln2downloads/pdb/current/AF-G3X712-F1.pdb", "url_external": "https://alphafold.ebi.ac.uk/entry/G3X712" } ], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "G3X712", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3X712" }, { "id": "PS50835", "database": "PROSITE", "url": "https://prosite.expasy.org/PS50835" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "Ig-like", "eco_id": "ECO_0000259", "start_pos": 22, "end_pos": 125, "start_aa": "Met", "end_aa": "Arg", "glycosite_overlap": [] } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "homologset.oma", "label": "OMA Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 44, "end_pos": 46 }, { "start_pos": 80, "end_pos": 82 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": 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"total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ], "tool_support": { "graph_view": "yes" } }, { "uniprot_canonical_ac": "G3X782-1", "uniprot_ac": "G3X782", "uniprot_id": "G3X782_BOVIN", "mass": { "chemical_mass": 45186.0, "monoisotopic_mass": 45186.0 }, "refseq": { "ac": "NP_001193023", "name": "choline/ethanolamine kinase", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001193023" }, "gene_names": [ { "name": "CHKB", "type": "recommended", "evidence": [ { "id": "G3X782", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3X782" } ] }, { "name": "CHKB", "type": "synonym", "evidence": [ { "id": "NP_001193023", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001193023" } ] } ], "protein_names": [ { "name": "Ethanolamine kinase", "type": "recommended", "evidence": [ { "id": "G3X782", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3X782/entry#names_and_taxonomy" } ] }, { "name": "2.7.1.32", "type": "synonym", "evidence": [ { "id": "G3X782", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3X782/entry#names_and_taxonomy" } ] }, { "name": "2.7.1.82", "type": "synonym", "evidence": [ { "id": "G3X782", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3X782/entry#names_and_taxonomy" } ] }, { "name": "choline/ethanolamine kinase", "type": "synonym", "evidence": [ { "id": "NP_001193023", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001193023" } ] } ], "function": [], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Bos taurus", "taxid": 9913, "evidence": [ { "database": "UniProtKB", "id": "G3X782", "url": "https://www.uniprot.org/uniprotkb/G3X782" } ], "common_name": "Bovine", "glygen_name": "Bovine", "reference_species": "Bos taurus [9913]" } ], "gene": [ { "name": "CHKB", "url": "https://www.uniprot.org/uniprotkb/G3X782", "locus": { "chromosome": "5", "start_pos": 119897490, "end_pos": 119901052, "strand": "+", "evidence": [ { "database": "Ensembl Gene", "id": "ENSBTAG00000016050", "url": "https://www.ensembl.org/id/ENSBTAG00000016050" } ] } } ], "crossref": [ { "id": "G3X782", "url": "https://alphafold.ebi.ac.uk/entry/G3X782", "database": "AlphaFoldDB", "categories": [] }, { "id": "ENSBTAG00000016050", "url": "https://bgee.org/?page=gene&gene_id=ENSBTAG00000016050", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "cd05156", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd05156", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "536213", "url": "https://www.ncbi.nlm.nih.gov/gene/536213", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR011009", "url": "https://www.ebi.ac.uk/interpro/entry/IPR011009", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "bta:536213", "url": "https://www.genome.jp/dbget-bin/www_bget?bta:536213", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "IETSIDY", "url": "https://omabrowser.org/oma/group/IETSIDY/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "A0A3Q1MPV1", "url": "https://www.orthodb.org/?gene=A0A3Q1MPV1", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "G3X782", "url": "https://www.orthodb.org/?gene=G3X782", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR22603", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR22603", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR22603:SF35", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR22603:SF35", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF01633", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF01633", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "R-BTA-1483191", "url": "https://www.reactome.org/PathwayBrowser/#R-BTA-1483191", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "R-BTA-1483213", "url": "https://www.reactome.org/PathwayBrowser/#R-BTA-1483213", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "NP_001193023", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001193023", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "12837", "url": "https://www.rhea-db.org/rhea/12837", "database": "Rhea", "categories": [ "Enzyme and Pathway" ] }, { "id": "13069", "url": "https://www.rhea-db.org/rhea/13069", "database": "Rhea", "categories": [ "Enzyme and Pathway" ] }, { "id": "A0A3Q1MPV1", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1MPV1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A3Q1MPV1-1", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1MPV1-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "G3X782", "url": "https://www.uniprot.org/uniprotkb/G3X782", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "G3X782-1", "url": "https://www.uniprot.org/uniprotkb/G3X782-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MAAEGTDVVGGGPLGGCLTKGSLLQAKCPDAAPSRRRGSARSRDAERRAYQWCREYLGGAWRQARPEELRVDPVSGGLSNLLFRCSLPDHLPSVGEEPREVLLRLYGAILQGVDSLVLESVMFAILAERSLGPQLYGVFPEGRLEQYIPSRPLKTHELRDPVLSAAIATKMAKFHGMEMPFTKEPHWLFGTMERYLKQIQDLPPTSLPQMNLLEMYSLKDEMGNLRKLLDTTPSPVVFCHNDIQEGNILLLSEPKNTDSLMLVDFEYSSYNYRGFDIGNHFCEWVYDYTHEEWPFYKAQPANYPTEGQQLHFLRHYLAEVKKDETISQEEQRKLEADLLVEANRYALASHFFWGLWSILQASMSTIEFGYLEYAQSRFQFYFQQKGQMTSFHPSS", "length": 395, "header": "tr|G3X782-1|G3X782_BOVIN Isoform 1 of Ethanolamine kinase OS=Bos taurus OX=9913 GN=CHKB PE=3 SV=1 CANONICAL=G3X782-1" }, "isoforms": [ { "isoform_ac": "A0A3Q1MPV1-1", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1MPV1/entry", "sequence": { "sequence": "MAAEGTDVVGGGPLGGCLTKGSLLQAKCPDAAPSRRRGSARSRDAERRAYQWCREYLGGAWRQARPEELRVDPVRWEVRGQPLLCARRVGLGPWGPSAFLGRGRAGGAGRGGWTPGRWNGRRAERALLWVCSGGLSNLLFRCSLPDHLPSVGEEPREVLLRLYGAILQGVDSLVLESVMFAILAERSLGPQLYGVFPEGRLEQYIPSRPLKTHELRDPVLSAAIATKMAKFHGMEMPFTKEPHWLFGTMERYLKQIQDLPPTSLPQMNLLEMYSLKDEMGNLRKLLDTTPSPVVFCHNDIQEGNILLLSEPKNTDSLMLVDFEYSSYNYRGFDIGNHFCEWVYDYTHEEWPFYKAQPANYPTEGQQLHFLRHYLAEVKKDETISQEEQRKLEADLLVEANRYALASHFFWGLWSILQASMSTIEFGYLEYAQSRFQFYFQQKGQMTSFHPSS", "length": 452, "header": "tr|A0A3Q1MPV1-1|A0A3Q1MPV1_BOVIN Computationally mapped isoform of Ethanolamine kinase OS=Bos taurus OX=9913 GN=CHKB PE=3 SV=1 CANONICAL=G3X782-1" }, "locus": { "chromosome": "5", "start_pos": 119900794, "end_pos": 119897717, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000074052.2", "url": "https://www.ensembl.org/id/ENSBTAT00000074052.2" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000073555.1", "url": "https://www.ensembl.org/id/ENSBTAP00000073555.1" } ] } }, { "isoform_ac": "G3X782-1", "url": "https://www.uniprot.org/uniprotkb/G3X782/entry", "sequence": { "sequence": "MAAEGTDVVGGGPLGGCLTKGSLLQAKCPDAAPSRRRGSARSRDAERRAYQWCREYLGGAWRQARPEELRVDPVSGGLSNLLFRCSLPDHLPSVGEEPREVLLRLYGAILQGVDSLVLESVMFAILAERSLGPQLYGVFPEGRLEQYIPSRPLKTHELRDPVLSAAIATKMAKFHGMEMPFTKEPHWLFGTMERYLKQIQDLPPTSLPQMNLLEMYSLKDEMGNLRKLLDTTPSPVVFCHNDIQEGNILLLSEPKNTDSLMLVDFEYSSYNYRGFDIGNHFCEWVYDYTHEEWPFYKAQPANYPTEGQQLHFLRHYLAEVKKDETISQEEQRKLEADLLVEANRYALASHFFWGLWSILQASMSTIEFGYLEYAQSRFQFYFQQKGQMTSFHPSS", "length": 395, "header": "tr|G3X782-1|G3X782_BOVIN Isoform 1 of Ethanolamine kinase OS=Bos taurus OX=9913 GN=CHKB PE=3 SV=1 CANONICAL=G3X782-1" }, "locus": { "chromosome": "5", "start_pos": 119900794, "end_pos": 119897717, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000021358.5", "url": "https://www.ensembl.org/id/ENSBTAT00000021358.5" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000021358.3", "url": "https://www.ensembl.org/id/ENSBTAP00000021358.3" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [ "enzyme" ], "publication": [], "pathway": [ { "id": "bta:536213", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?bta:536213", "resource": "KEGG Pathway" }, { "id": "R-BTA-1483191", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-BTA-1483191", "resource": "Reactome", "description": "Synthesis of PC" }, { "id": "R-BTA-1483213", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-BTA-1483213", "resource": "Reactome", "description": "Synthesis of PE" } ], "orthologs": [ { "uniprot_canonical_ac": "A0A9J7JVD0-1", "protein_name": "Ethanolamine kinase", "gene_name": "Chkb", "tax_id": 10029, "organism": "Cricetulus griseus", "sequence": { "sequence": "MAADRTGVAGGGTVGGCLTKDSLQDAKCPAAVPNRRRASSLSRDAQRRAYQWCREYLGGAWRRARPEELSVCPVRSEVNLGVLKTLPISMLGGLSNLLFRCSLPNHLPSVGEEPREVLLRLYGAILQGVDSLVLESVMFAILAERALGPQLYGVFPEGRLEQYLPSRPLKTQELRDPVLSGAIATKMARFHGMEMPFTKEPHWLFGTMERYLKQIQDLPSTDLPQMNLLEMYNLKDEMGNLRKLLDATPSPVVFCHNDIQEGNILLLSEPKSDDSLMLVDFEYSSYNYRGFDIGNHFCEWVYDYTFEEWPFYKASPTDYPTRGQQLHFIRHYLAEVQKGQILPEEEQKKLEEELLMEVSWYALASHFFWGLWSILQASMSTIEFGYLEYAQSRFQFYFKQKGQLTGFHSSP", "length": 411 }, "evidence": [ { "id": "G3X782", "url": "https://omabrowser.org/oma/group/G3X782/", "database": "OMA" } ], "glygen_name": "Hamster", "common_name": "Chinese hamster" }, { "uniprot_canonical_ac": "D2D0E0-1", "protein_name": "Ethanolamine kinase", "gene_name": "CHKB", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MAAEGTAVAGGGAVGGLLAKDSLLQSKCPDAAPSRRRGSARSRDAERRAYQWCREYLGGAWRRVRPEELRVDPVSGGLSNLLFRCSLPDHLPSVGEEPREVLLRLYGAILQGVDSLVLESVMFAILAERALGPQLYGVFPEGRLEQYIPSRPLKTHELREPVLSAAIATKMARFHGMEMPFTKEPHWLFGTMERYLKQIQDLPPTGLPQMNLLEMYSLKEEMGSLRKLLDTTPSPVVFCHNDIQEGNILLLSEPENADSLMLVDFEYSSYNYRGFDIGNHFCEWVYDYTHEEWPFYKAQPADYPTRGQQLHFIRHYLAEVKKGETISQEEQRKLEADLLVEANRYALASHFFWGLWSILQASMSTIEFGYLEYAQSRFQSYFQQKAQLTSLQPSS", "length": 395 }, "evidence": [ { "id": "G3X782", "url": "https://omabrowser.org/oma/group/G3X782/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "O54783-1", "protein_name": "Choline/ethanolamine kinase", "gene_name": "Chkb", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MAADGTGVVGGGAVGGPLSKDGLLDAKCPEPIPNRRRSSSLSRDAQRRAYQWCREYLGGAWRRARPEELSVCPVSGGLSNLLFRCSLPNHVPSMGGEPREVLLRLYGAILQGVDSLVLESVMFAILAERSLGPQLYGVFPEGRLEQYLPSRPLKTQELRDPVLSGAIATKMARFHGMEMPFTKEPRWLFGTMERYLKQIQDLPSTSLPQMNLVEMYSLKDEMNHLRTLLDATPSPVVFCHNDIQEGNILLLSEPDSDDNLMLVDFEYSSYNYRGFDIGNHFCEWVYDYTYEEWPFYKARPADYPTREQQLLFIRHYLAEVQKGEVLSEEEQKKQEEDLLIEISRYALASHFFWGLWSTLQASMSTIEFGYLEYAQSRFQFYFQQKGQLTSFLSP", "length": 394 }, "evidence": [ { "id": "G3X782", "url": "https://omabrowser.org/oma/group/G3X782/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "O55229-1", "protein_name": "Choline/ethanolamine kinase", "gene_name": "Chkb", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MAADGTGVVGGGAVGGGLPKDGLQDAKCPEPIPNRRRASSLSRDAQRRAYQWCREYLGGAWRRARPEELSVCPVSGGLSNLLFRCSLPNHVPSVGGEPREVLLRLYGAILQGVDSLVLESVMFAILAERSLGPQLYGVFPEGRLEQYLPSRPLKTQELRDPVLSGAIATRMARFHGMEMPFTKEPRWLFGTMERYLKQIQDLPSTSLPQMNLVEMYSLKDEMNSLRKLLDDTPSPVVFCHNDIQEGNILLLSEPDSDDNLMLVDFEYSSYNYRGFDIGNHFCEWVYDYTYEEWPFYKARPTDYPTREQQLHFIRHYLAEVQKGEILSEEEQKKREEELLLEISRYSLASHFFWGLWSTLQASMSTIEFGYLEYAQSRFQFYFQQKGQLTSSPSS", "length": 394 }, "evidence": [ { "id": "G3X782", "url": "https://omabrowser.org/oma/group/G3X782/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q554D8-1", "protein_name": "Probable ethanolamine kinase B", "gene_name": "etnkB", "tax_id": 44689, "organism": "Dictyostelium discoideum", "sequence": { "sequence": "MNEFEDIIYPGPSHVTTNIEFEDENIENNENYLNLVQILKELVDNNLKEEIEFKPMVGGVTNTLFKSSFITGQGSNKSVIIRLYGKGSEQFIDRKTEANIQYLLSKNGVGPKFYGTFENGCIYGYVEGDQLQLEDLYQNNILSLIAKETGRWHSLKLDINSNSQLLLSSSSDSSIKESTTISTSTSTSTSTSSTSPSTSPSLENSTLSPRNMNTQTSSTSLFKNLNSWINNAMTLTSKESKGSMISKINLNRYKEEAMSLMSFIEEHYSGEEYINFCHNDLIPRNMIYNKEKGQVKFIDFEYSGYNFRGYDIGNFFCEFSGLDLDYTKYPSIEIQKRFIKNYLISINNCKNIQQKQKQKQQQQQIQNSINDENMDIENDELLYEPSKEEIHNLYIESNHLTLGSHLMWGFWGIIQHFSSSIDFDYIDYAIKRFKQYDLVKNKVLSLK", "length": 447 }, "evidence": [ { "id": "G3X782", "url": "https://omabrowser.org/oma/group/G3X782/", "database": "OMA" } ], "glygen_name": "Cellular slime mold", "common_name": "Social amoeba" }, { "uniprot_canonical_ac": "Q8IMF4-1", "protein_name": "Uncharacterized protein", "gene_name": "Dmel\\CG2201", "tax_id": 7227, "organism": "Drosophila melanogaster", "sequence": { "sequence": "MKQRNLRNNKALKRLQQPDNKNLNCCLSKRCNYENIWQHFNSNATLEEIRHAAARICRDYLTGPWKVVTPESLVVKRISGGLSNFLYYVSLPDLNDYDELDEQKQQQEDIIGATATVTNRSGVFIHDDESAAKAVGVTLMARELINNDDVADAAPGATQAHKRQRCDSNSRECSSSKRLHAPKQQPREVLLRIYGQTHGDHALESMITESVVFALLSERNYGPKLHGIFPGGRIEQYIPARALTTAELGEQRILKRVAEKMGEIHSLNIPMSKEPDWIWNCMQRWVSGLESIVNGSVQTNQKSSVLKKQMELMRTFDYVQEMAWIRSIIDEGDYPVVFCHNDLQEGNILMRQPSAGQNERTPRESISSLRSNFDETLGDSLDGNSNISDTETHKSRSVSPSPCPELDTTNDSALDSSFMADNEPDLIIIDFEYCAYNYRGYDLANHFIEWTFDYTNPQFPYFYHNSSNCATVQQRRDFIVNYLKKFHDDENYNITGQELMKVDAEIQFFTMLSHLFWSLWSVINVTSAIEFGYWEYGIARILEYQKLKAAYQAN", "length": 554 }, "evidence": [ { "id": "G3X782", "url": "https://omabrowser.org/oma/group/G3X782/", "database": "OMA" } ], "glygen_name": "Fruit fly", "common_name": "Fruit fly" }, { "uniprot_canonical_ac": "Q9Y259-1", "protein_name": "Choline/ethanolamine kinase", "gene_name": "CHKB", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MAAEATAVAGSGAVGGCLAKDGLQQSKCPDTTPKRRRASSLSRDAERRAYQWCREYLGGAWRRVQPEELRVYPVSGGLSNLLFRCSLPDHLPSVGEEPREVLLRLYGAILQGVDSLVLESVMFAILAERSLGPQLYGVFPEGRLEQYIPSRPLKTQELREPVLSAAIATKMAQFHGMEMPFTKEPHWLFGTMERYLKQIQDLPPTGLPEMNLLEMYSLKDEMGNLRKLLESTPSPVVFCHNDIQEGNILLLSEPENADSLMLVDFEYSSYNYRGFDIGNHFCEWVYDYTHEEWPFYKARPTDYPTQEQQLHFIRHYLAEAKKGETLSQEEQRKLEEDLLVEVSRYALASHFFWGLWSILQASMSTIEFGYLDYAQSRFQFYFQQKGQLTSVHSSS", "length": 395 }, "evidence": [ { "id": "G3X782", "url": "https://omabrowser.org/oma/group/G3X782/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" } ], "go_annotation": { "categories": [ { "name": "Biological Process", "total": 2, "go_terms": [ { "name": "CDP-choline pathway", "id": "GO:0006657", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006657", "evidence": [ { "database": "UniProtKB", "id": "G3X782", "url": "https://www.uniprot.org/uniprotkb/G3X782" } ], "pmid": "" }, { "name": "phosphatidylethanolamine biosynthetic process", "id": "GO:0006646", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006646", "evidence": [ { "database": "UniProtKB", "id": "G3X782", "url": "https://www.uniprot.org/uniprotkb/G3X782" } ], "pmid": "" } ] }, { "name": "Molecular Function", "total": 3, "go_terms": [ { "name": "ATP binding", "id": "GO:0005524", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005524", "evidence": [ { "database": "UniProtKB", "id": "G3X782", "url": "https://www.uniprot.org/uniprotkb/G3X782" } ], "pmid": "" }, { "name": "choline kinase activity", "id": "GO:0004103", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0004103", "evidence": [ { "database": "UniProtKB", "id": "G3X782", "url": "https://www.uniprot.org/uniprotkb/G3X782" } ], "pmid": "" }, { "name": "ethanolamine kinase activity", "id": "GO:0004305", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0004305", "evidence": [ { "database": "UniProtKB", "id": "G3X782", "url": "https://www.uniprot.org/uniprotkb/G3X782" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 1, "go_terms": [ { "name": "cytoplasm", "id": "GO:0005737", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005737", "evidence": [ { "database": "UniProtKB", "id": "G3X782", "url": "https://www.uniprot.org/uniprotkb/G3X782" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [], "ptm_annotation": [], "interactions": [], "reactions": [ { "id": "12837", "name": "", "equation": "choline + ATP = phosphocholine + ADP + H(+)", "summary": "", "cellular_location": "", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [ "A0A3Q1LRY5-1", "G3X782-1" ], "evidence": [ { "id": "12837", "database": "Rhea", "url": "https://www.rhea-db.org/rhea/12837" } ] }, { "id": "13069", "name": "", "equation": "ethanolamine + ATP = phosphoethanolamine + ADP + H(+)", "summary": "", "cellular_location": "", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [ "A0A3Q1LRY5-1", "G3X782-1" ], "evidence": [ { "id": "13069", "database": "Rhea", "url": "https://www.rhea-db.org/rhea/13069" } ] }, { "id": "R-BTA-1483004", "name": "Cho is phosphorylated to PCho by CHK dimer", "equation": "", "summary": "This event has been computationally inferred from an event that has been demonstrated in another species.

The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.

More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "cellular_location": "cytosol", "input_participant_list": [ "R-ALL-264618" ], "output_participant_list": [ "R-ALL-1524071" ], "enzyme_list": [ "G3X782-1", "A0A3Q1LRY5-1" ], "evidence": [ { "id": "R-BTA-1483004", "database": "Reactome", "url": "https://www.reactome.org/PathwayBrowser/#R-BTA-1483004" } ] }, { "id": "R-BTA-1483222", "name": "ETA is phosphorylated to PETA by CHK/ETNK", "equation": "", "summary": "This event has been computationally inferred from an event that has been demonstrated in another species.

The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.

More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "cellular_location": "cytosol", "input_participant_list": [ "R-ALL-1498751" ], "output_participant_list": [], "enzyme_list": [ "G3X782-1", "F1N378-1", "A0A3Q1LRY5-1", "F1MRD9-1" ], "evidence": [ { "id": "R-BTA-1483222", "database": "Reactome", "url": "https://www.reactome.org/PathwayBrowser/#R-BTA-1483222" } ] } ], "reaction_participants": [ { "participant_id": "R-ALL-1498751", "participant_name": "ETA [cytosol]", "crossref": [ { "id": "57603", "database": "ChEBI", "url": "" }, { "id": "ZINC000008214617", "database": "ZINC", "url": "" } ] }, { "participant_id": "R-ALL-1524071", "participant_name": "PCho [cytosol]", "crossref": [ { "id": "36700", "database": "ChEBI", "url": "" } ] }, { "participant_id": "R-ALL-264618", "participant_name": "Cho [cytosol]", "crossref": [ { "id": "15354", "database": "ChEBI", "url": "" }, { "id": "4551", "database": "Guide to Pharmacology - Ligands", "url": "" }, { "id": "ZINC000003079337", "database": "ZINC", "url": "" }, { "id": "HMDB0000097", "database": "HMDB Metabolite", "url": "" } ] } ], "reaction_enzymes": [ { "uniprot_ac": "A0A3Q1LRY5", "gene_name": "CHKA", "activity": [ { "ec_number": "2.7.1.32", "activity": "choline + ATP = phosphocholine + ADP + H(+).", "evidence": [ { "id": "A0A3Q1LRY5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1LRY5" } ] }, { "ec_number": "2.7.1.82", "activity": "ethanolamine + ATP = phosphoethanolamine + ADP + H(+).", "evidence": [ { "id": "A0A3Q1LRY5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1LRY5" } ] }, { "ec_number": "2.7.1.32", "activity": "", "evidence": [ { "id": "A0A3Q1LRY5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1LRY5" } ] }, { "ec_number": "2.7.1.82", "activity": "", "evidence": [ { "id": "A0A3Q1LRY5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1LRY5" } ] } ] }, { "uniprot_ac": "F1MRD9", "gene_name": "ETNK2", "activity": [ { "ec_number": "2.7.1.82", "activity": "ethanolamine + ATP = phosphoethanolamine + ADP + H(+).", "evidence": [ { "id": "F1MRD9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MRD9" } ] }, { "ec_number": "2.7.1.82", "activity": "", "evidence": [ { "id": "F1MRD9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MRD9" } ] } ] }, { "uniprot_ac": "F1N378", "gene_name": "ETNK1", "activity": [ { "ec_number": "2.7.1.82", "activity": "ethanolamine + ATP = phosphoethanolamine + ADP + H(+).", "evidence": [ { "id": "F1N378", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1N378" } ] }, { "ec_number": "2.7.1.82", "activity": "", "evidence": [ { "id": "F1N378", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1N378" } ] } ] }, { "uniprot_ac": "G3X782", "gene_name": "CHKB", "activity": [ { "ec_number": "2.7.1.32", "activity": "choline + ATP = phosphocholine + ADP + H(+).", "evidence": [ { "id": "G3X782", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3X782" } ] }, { "ec_number": "2.7.1.82", "activity": "ethanolamine + ATP = phosphoethanolamine + ADP + H(+).", "evidence": [ { "id": "G3X782", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3X782" } ] }, { "ec_number": "2.7.1.32", "activity": "", "evidence": [ { "id": "G3X782", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3X782" } ] }, { "ec_number": "2.7.1.82", "activity": "", "evidence": [ { "id": "G3X782", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3X782" } ] } ] } ], "biomarkers": [], "structures": [ { "pdb_id": "AF-G3X782-F1", "pdb_chain": "global", "start_pos": 1, "end_pos": 395, "overlap": "1.0", "method": "AlphaFold", "type": "alphafold", "resolution": -1.0, "url": "https://data.glygen.org/ln2downloads/pdb/current/AF-G3X782-F1.pdb", "url_external": "https://alphafold.ebi.ac.uk/entry/G3X782" } ], "lectin_list": [], "domain_list": [], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [ { "ec_number": "2.7.1.32", "ec_name": "choline + ATP = phosphocholine + ADP + H(+).", "evidence": [ { "id": "2.7.1.32", "database": "Rhea", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.1.32" }, { "id": "2.7.1.32", "database": "BRENDA Enzymes", "url": "https://www.brenda-enzymes.org/enzyme.php?ecno=2.7.1.32" } ] }, { "ec_number": "2.7.1.82", "ec_name": "ethanolamine + ATP = phosphoethanolamine + ADP + H(+).", "evidence": [ { "id": "2.7.1.82", "database": "Rhea", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.1.82" }, { "id": "2.7.1.82", "database": "BRENDA Enzymes", "url": "https://www.brenda-enzymes.org/enzyme.php?ecno=2.7.1.82" } ] } ], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" }, { "name": "homologset.oma", "label": "OMA Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], 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"sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": 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"total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ], "tool_support": { "graph_view": "yes" } }, { "uniprot_canonical_ac": "G3X7I5-1", "uniprot_ac": "G3X7I5", "uniprot_id": "G3X7I5_BOVIN", "mass": { "chemical_mass": 13051.0, "monoisotopic_mass": 13051.0 }, "refseq": {}, "gene_names": [], "protein_names": [ { "name": "Ig-like domain-containing protein", "type": "recommended", "evidence": [ { "id": "G3X7I5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3X7I5/entry#names_and_taxonomy" } ] } ], "function": [], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Bos taurus", "taxid": 9913, "evidence": [ { "database": "UniProtKB", "id": "G3X7I5", "url": "https://www.uniprot.org/uniprotkb/G3X7I5" } ], "common_name": "Bovine", "glygen_name": "Bovine", "reference_species": "Bos taurus [9913]" } ], "gene": [ { "name": "", "url": "https://www.uniprot.org/uniprotkb/G3X7I5", "locus": {} } ], "crossref": [ { "id": "G3X7I5", "url": "https://alphafold.ebi.ac.uk/entry/G3X7I5", "database": "AlphaFoldDB", "categories": [] }, { "id": "ENSBTAG00000046322", "url": "https://bgee.org/?page=gene&gene_id=ENSBTAG00000046322", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "IPR003599", "url": "https://www.ebi.ac.uk/interpro/entry/IPR003599", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR007110", "url": "https://www.ebi.ac.uk/interpro/entry/IPR007110", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR013106", "url": "https://www.ebi.ac.uk/interpro/entry/IPR013106", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR013783", "url": "https://www.ebi.ac.uk/interpro/entry/IPR013783", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR036179", "url": "https://www.ebi.ac.uk/interpro/entry/IPR036179", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR050150", "url": "https://www.ebi.ac.uk/interpro/entry/IPR050150", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "AGGVSWY", "url": "https://omabrowser.org/oma/group/AGGVSWY/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "PTHR23267", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR23267", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF07686", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF07686", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "G3X7I5", "url": "https://www.uniprot.org/uniprotkb/G3X7I5", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "G3X7I5-1", "url": "https://www.uniprot.org/uniprotkb/G3X7I5-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { 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"url": "https://www.ensembl.org/id/ENSBTAP00000030614.7" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [], "orthologs": [], "go_annotation": { "categories": [ { "name": "Biological Process", "total": 1, "go_terms": [ { "name": "immune response", "id": "GO:0006955", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006955", "evidence": [ { "database": "UniProtKB", "id": "G3X7I5", "url": "https://www.uniprot.org/uniprotkb/G3X7I5" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 1, "go_terms": [ { "name": "immunoglobulin complex", "id": "GO:0019814", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0019814", "evidence": [ { "database": "UniProtKB", "id": "G3X7I5", "url": "https://www.uniprot.org/uniprotkb/G3X7I5" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [ { "pdb_id": "AF-G3X7I5-F1", "pdb_chain": "global", "start_pos": 1, "end_pos": 123, "overlap": "1.0", "method": "AlphaFold", "type": "alphafold", "resolution": -1.0, "url": "https://data.glygen.org/ln2downloads/pdb/current/AF-G3X7I5-F1.pdb", "url_external": "https://alphafold.ebi.ac.uk/entry/G3X7I5" } ], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "G3X7I5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3X7I5" }, { "id": "PS50835", "database": "PROSITE", "url": "https://prosite.expasy.org/PS50835" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "Ig-like", "eco_id": "ECO_0000259", "start_pos": 1, "end_pos": 90, "start_aa": "Gln", "end_aa": "Cys", "glycosite_overlap": [] } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", 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"table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ], "tool_support": { "graph_view": "yes" } }, { "uniprot_canonical_ac": "G3X7J5-1", "uniprot_ac": "G3X7J5", "uniprot_id": "G3X7J5_BOVIN", "mass": { "chemical_mass": 44765.0, "monoisotopic_mass": 44765.0 }, "refseq": { "ac": "XP_002691726", "name": "torsin-4A", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_002691726" }, "gene_names": [ { "name": "TOR4A", "type": "recommended", "evidence": [ { "id": "G3X7J5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3X7J5" } ] }, { "name": "TOR4A", "type": "synonym", "evidence": [ { "id": "XP_002691726", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_002691726" } ] } ], "protein_names": [ { "name": "Torsin-4A", "type": "recommended", "evidence": [ { "id": "G3X7J5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3X7J5/entry#names_and_taxonomy" } ] }, { "name": "Torsin family 4 member A", "type": "synonym", "evidence": [ { "id": "G3X7J5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3X7J5/entry#names_and_taxonomy" } ] }, { "name": "torsin-4A", "type": "synonym", "evidence": [ { "id": "XP_002691726", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_002691726" } ] } ], "function": [], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Bos taurus", "taxid": 9913, "evidence": [ { "database": "UniProtKB", "id": "G3X7J5", "url": "https://www.uniprot.org/uniprotkb/G3X7J5" } ], "common_name": "Bovine", "glygen_name": "Bovine", "reference_species": "Bos taurus [9913]" } ], "gene": [ { "name": "TOR4A", "url": "https://www.uniprot.org/uniprotkb/G3X7J5", "locus": { "chromosome": "11", "start_pos": 106282532, "end_pos": 106275898, "strand": "-", "evidence": [ { "database": "Ensembl Gene", "id": "ENSBTAG00000023787", "url": "https://www.ensembl.org/id/ENSBTAG00000023787" } ] } } ], "crossref": [ { "id": "ENSBTAG00000023787", "url": "https://bgee.org/?page=gene&gene_id=ENSBTAG00000023787", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "618444", "url": "https://www.ncbi.nlm.nih.gov/gene/618444", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR003593", "url": "https://www.ebi.ac.uk/interpro/entry/IPR003593", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR010448", "url": "https://www.ebi.ac.uk/interpro/entry/IPR010448", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR027417", "url": "https://www.ebi.ac.uk/interpro/entry/IPR027417", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "bta:618444", "url": "https://www.genome.jp/dbget-bin/www_bget?bta:618444", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "EFAITGC", "url": "https://omabrowser.org/oma/group/EFAITGC/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "G3X7J5", "url": "https://www.orthodb.org/?gene=G3X7J5", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR10760", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR10760", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR10760:SF1", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR10760:SF1", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF06309", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF06309", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "R-BTA-114608", "url": "https://www.reactome.org/PathwayBrowser/#R-BTA-114608", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "XP_002691726", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_002691726", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "G3X7J5", "url": "https://www.uniprot.org/uniprotkb/G3X7J5", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "G3X7J5-1", "url": "https://www.uniprot.org/uniprotkb/G3X7J5-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MDRGQSSPEPSAPVAPSPSVIAPVRAVVRLRHQVHLLRKRRPPSPAVAPDPGAAALRVPREQPQFFTFDGPAERASRPARKRRRRSRLVLYPETSRKFGPRAERQSRAQRCLLLLVAIVGFQVLNAIENLDDNALRYDLDGLEKTLQRAVFGQPAAVGRLVALLRDYLATHVHSRPLLLALHGPSGVGKSHVGRLLARHFRAVLEDGALVLQYHTRHHCPAPRAATGCREELARRVADVLARAEAEEKTPLLVLDDAELLPPALLDELHGLLQPQRPPRFHNAVYVLLSGAGGAEVTRFVLQNASRAGRADGAEELRAAEEELRASLHALLVRQHPLWEAAAIVPFLLLDKRDVVNCFRDEMAGEGFFPEQARAELLAAQLSYYRVAGREFAVNGCKQVVAAVNLL", "length": 406, "header": "tr|G3X7J5-1|G3X7J5_BOVIN Isoform 1 of Torsin-4A OS=Bos taurus OX=9913 GN=TOR4A PE=3 SV=1 CANONICAL=G3X7J5-1" }, "isoforms": [ { "isoform_ac": "G3X7J5-1", "url": "https://www.uniprot.org/uniprotkb/G3X7J5/entry", "sequence": { "sequence": "MDRGQSSPEPSAPVAPSPSVIAPVRAVVRLRHQVHLLRKRRPPSPAVAPDPGAAALRVPREQPQFFTFDGPAERASRPARKRRRRSRLVLYPETSRKFGPRAERQSRAQRCLLLLVAIVGFQVLNAIENLDDNALRYDLDGLEKTLQRAVFGQPAAVGRLVALLRDYLATHVHSRPLLLALHGPSGVGKSHVGRLLARHFRAVLEDGALVLQYHTRHHCPAPRAATGCREELARRVADVLARAEAEEKTPLLVLDDAELLPPALLDELHGLLQPQRPPRFHNAVYVLLSGAGGAEVTRFVLQNASRAGRADGAEELRAAEEELRASLHALLVRQHPLWEAAAIVPFLLLDKRDVVNCFRDEMAGEGFFPEQARAELLAAQLSYYRVAGREFAVNGCKQVVAAVNLL", "length": 406, "header": "tr|G3X7J5-1|G3X7J5_BOVIN Isoform 1 of Torsin-4A OS=Bos taurus OX=9913 GN=TOR4A PE=3 SV=1 CANONICAL=G3X7J5-1" }, "locus": { "chromosome": "11", "start_pos": 106279137, "end_pos": 106277920, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000124046.1", "url": "https://www.ensembl.org/id/ENSBTAT00000124046.1" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000092918.1", "url": "https://www.ensembl.org/id/ENSBTAP00000092918.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [ { "id": "bta:618444", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?bta:618444", "resource": "KEGG Pathway" }, { "id": "R-BTA-114608", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-BTA-114608", "resource": "Reactome", "description": "Platelet degranulation" } ], "orthologs": [ { "uniprot_canonical_ac": "D3ZG57-1", "protein_name": "Torsin-4A", "gene_name": "Tor4a", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MDRGHPSLEPQAKGPCVIAPVRAVLRLRRRVCVLRKRRLLQTGTEPSVGTGTLGSSASLGTLRADLDQPKFFTFDSLTELSSRTPRKRRRRSRVVLYPETSRKCRPRTERQSRAQRCLLLLVAIVGFQVLNAIENLDDNAQRYDLDGLEKALQRSVFGQPAAVSRIMALLRDYLATHVHSHPLLLALHGPSGVGKSHVGRLLARHFRAVLEDGALVLQYHARHHCPELRPVQDCRKELAQRVADVVAQAEAEEKTPLLVLDEAELLPPALLDELHDLLQPQRSHHFHNAIYVLLSGAGGIEITHFVLQNASRMLPSLRHSVGRTQTEESPALEELQTSLRELLAREHPLWHTAAIVPFLLLDKPDVVNCFREEMAGEGFFPEQAQAEHLAEQLSYYHVAGHEFAITGCKQVVAKVNLLQHKPAHAGHESVGPGV", "length": 434 }, "evidence": [ { "id": "G3X7J5", "url": "https://omabrowser.org/oma/group/G3X7J5/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "F1NLT2-1", "protein_name": "Torsin family 4 member A", "gene_name": "TOR4A", "tax_id": 9031, "organism": "Gallus gallus", "sequence": { "sequence": "MDGELLGTEVDGEAPTAMGDVGGEASCAEGDAKGEVSCAEVGGELPTAMGDAAEEASCAESGAKEEGPYADGHVEGEMGCSDSDGEGELRCATTDVKEEASCSESEGEEVPDAEIPAASKRVSFISSPLRAIVRLKQRYRVQKKGRLHFELPQEKSSEPVHARVLQRQFSLNRSGLYGSSKSFFNQSGFKTSQYFTFDTSVEEWAMSKPRRKKKRRKSRVVLYPDKTKRYLPAEEKSNAKRCLLLLIVIIFFQILNAIENLDDNLQKYDLDGLEKTMHREVFGQKLAVESIMQLLKDYLATHIHNKPLVLSLNGPTGVGKSHVGWLLAKHFRSVMDNDFVLQYFVMHHCPSGAAPLTCETDLSKKISDMVTRAEIEEKIPLFILDEVELMSPVLLDTLSRFFEPNQTNEFLNAIYILISNIGGGEITKFVIQNASAELLQQRSGAEELLSVIQPVLTHTHPLWKAADVVPFVLLERSHVIDCFLEEMRREGLYPEQSHVERLASQLSYYTTGDKQFSRLGCKQVVAKVNLL", "length": 531 }, "evidence": [ { "id": "G3X7J5", "url": "https://omabrowser.org/oma/group/G3X7J5/", "database": "OMA" } ], "glygen_name": "Chicken", "common_name": "Chicken" }, { "uniprot_canonical_ac": "F1RVY0-1", "protein_name": "Torsin-4A", "gene_name": "TOR4A", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MDRGQPSPEPAAAAPARGPNVIAPVRAVVRLRRRVCLLRTRRLPTPGAGPDFGPGAPRANLHQPQFFTFEGPAELSSRAPRKRRRRSRVVLYPETSRKYRPQAERRSRAQRCLLLLVAIVGFQVLNAIENLDDNALRYDLDGLEKALQRAVFGQPSAVGRIVALLRDYLATHVHSRPLLLALHGPSGVGKSHVGRLLARHFRAVLEDSALVLQYDARHHCPDPRAAQDCREELAQRVADVVARAEAEEKTPLLVLDEVELLPQALLDELHGFLQPQRSHHFHNAIYVLLSGAGGAEVTRFVLQNASRALALRPDGAHGARAAAMAAQAEEELRVRLQALLVREHPLWQAAAIVPFLLLDKRDVVNCFRDEMAGEGFFPEQAHAELLAARLSYYRVAGREFAVTGCKQVVATVNLL", "length": 415 }, "evidence": [ { "id": "G3X7J5", "url": "https://omabrowser.org/oma/group/G3X7J5/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "Q568B8-1", "protein_name": "Torsin-4A", "gene_name": "tor4a", "tax_id": 7955, "organism": "Danio rerio", "sequence": { "sequence": "MGEQDPSDRLRGDQLKEPNQNGKGSFSQFSSSVRAMVRIRMKYQAIKKRRMEIASATPQIFTSPRSTSPKVFTFDNLHEPVNSNPASPRKRKKKRKGRVLYPTSSLRAVPTKESSRAKNCLYLLCIIVFLQVYNAIENLDDHVLKYDLEGLEKTLKREVFGQQEVAEGLLGHLQDYLSTYVHNKPLVLSFHGPTGVGKSHVGRLLAQHFRSVVGEELVMQYFVLHHCPTDDDIPVCTKSLESHISEMVSQGEEEEKIPVFIFDEVEHMPRQLMDTLRELIQPQNSNKYLNAIYILISNLGHEDITKFVLHNSSIAISGRLSLTQELTPWLRNYLQEHHGLFLDAEYLPFMLLEKSHVMDCFIDEMSREGFYPDRSHVERLAEELSYYIVGEREFSHTGCRQVVAKVNLL", "length": 409 }, "evidence": [ { "id": "G3X7J5", "url": "https://omabrowser.org/oma/group/G3X7J5/", "database": "OMA" } ], "glygen_name": "Zebrafish", "common_name": "Zebrafish" }, { "uniprot_canonical_ac": "Q8BH02-1", "protein_name": "Torsin-4A", "gene_name": "Tor4a", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MDRSHPSLEPQAKGPCVIAPVRAVLRLRRRVCVLRKRRLLQPGTEPDSGTGTLGPTGSLGTLRADLDQPKFFTFDSLTELTSRTPRKRRRRSRVVLYPETSRKCRPRTERQSRAQRCLLLLVAIVGFQVLNAIENLDDNAQRYDLDGLEKALQRSVFGQPAAVGRIMALLRDYLATHVHSHPLLLALHGPSGVGKSHVGRLLARHFRAVLEDGALVLQYHARYHCPEPRPVQDCRKELAQRVADVVAQAEAEEKTPLLVLDEAELLPPALLDELHDLLQPQRSHHFHNAIYVLLSGAGGIEITHFVLQNASRMLPPLRHSAGSTQTEESPAQELLTSLRELLAREHPLWHTAAIVPFLLLDKPDVVNCFREEMAGEGFFPEQALAEHLAEQLSYYHVAGHEFAITGCKQVVAKVNLLQHKPAHAGH", "length": 426 }, "evidence": [ { "id": "G3X7J5", "url": "https://omabrowser.org/oma/group/G3X7J5/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q9NXH8-1", "protein_name": "Torsin-4A", "gene_name": "TOR4A", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": 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"database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "G3X7R6-1", "url": "https://www.uniprot.org/uniprotkb/G3X7R6-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MFARGLKRKCSEEEAPADPLQRQSLLDMSLVKLQLCHMLAEPNLCRSVLIANTVRQIQEEMTQDGSWCLPGPQTAGRLPRDRLVSTEILCRSARAGPPQAPDPADLASALQAVPAIQVPGAVPAGPWGRAGPGESRGGFPRSLDQVFDTLESHSPGTVEELFSDVDGPYYDLDAVLTGMVGGAKSGPEGLETFASAAAPPPGTGCKADLGELDHVVEILVET", "length": 222, "header": "tr|G3X7R6-1|G3X7R6_BOVIN Isoform 1 of Cell division cycle associated 4 OS=Bos taurus OX=9913 GN=CDCA4 PE=4 SV=1 CANONICAL=G3X7R6-1" }, "isoforms": [ { "isoform_ac": "G3X7R6-1", "url": "https://www.uniprot.org/uniprotkb/G3X7R6/entry", "sequence": { "sequence": "MFARGLKRKCSEEEAPADPLQRQSLLDMSLVKLQLCHMLAEPNLCRSVLIANTVRQIQEEMTQDGSWCLPGPQTAGRLPRDRLVSTEILCRSARAGPPQAPDPADLASALQAVPAIQVPGAVPAGPWGRAGPGESRGGFPRSLDQVFDTLESHSPGTVEELFSDVDGPYYDLDAVLTGMVGGAKSGPEGLETFASAAAPPPGTGCKADLGELDHVVEILVET", "length": 222, "header": "tr|G3X7R6-1|G3X7R6_BOVIN Isoform 1 of Cell division cycle associated 4 OS=Bos taurus OX=9913 GN=CDCA4 PE=4 SV=1 CANONICAL=G3X7R6-1" }, "locus": { "chromosome": "21", "start_pos": 69410675, "end_pos": 69410010, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000096225.1", "url": "https://www.ensembl.org/id/ENSBTAT00000096225.1" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000075050.1", "url": "https://www.ensembl.org/id/ENSBTAP00000075050.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [ { "id": "bta:527837", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?bta:527837", "resource": "KEGG Pathway" } ], "orthologs": [ { "uniprot_canonical_ac": "G3H3A4-1", "protein_name": "Cell division cycle-associated protein 4", "gene_name": "Cdca4", "tax_id": 10029, "organism": "Cricetulus griseus", "sequence": { "sequence": "MFARGLKRKYGDQEEGVEGFGTVPSYSLQRQSLLDMSLVKLQLCHMLVEPNLCRSVLIANTVRQIQEEMSRDGVWHGMAPQNVERAPIDRLVSTEILCRTARAADEEHPTPELEDGPLQSSASELPIVSPAQGQRSPPSSLWELDNPQENRGSFQKSLDQIFETLENKSPSSVEELFSDVDSSYYDLDTVLTGMMGGTKPSLCSGLESFAAAAPPPSSTCKSDLAELDHVVEILVET", "length": 237 }, "evidence": [ { "id": "G3X7R6", "url": "https://omabrowser.org/oma/group/G3X7R6/", "database": "OMA" } ], "glygen_name": "Hamster", "common_name": "Chinese hamster" }, { "uniprot_canonical_ac": "Q9BXL8-1", "protein_name": "Cell division cycle-associated protein 4", "gene_name": "CDCA4", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MFARGLKRKCVGHEEDVEGALAGLKTVSSYSLQRQSLLDMSLVKLQLCHMLVEPNLCRSVLIANTVRQIQEEMTQDGTWRTVAPQAAERAPLDRLVSTEILCRAAWGQEGAHPAPGLGDGHTQGPVSDLCPVTSAQAPRHLQSSAWEMDGPRENRGSFHKSLDQIFETLETKNPSCMEELFSDVDSPYYDLDTVLTGMMGGARPGPCEGLEGLAPATPGPSSSCKSDLGELDHVVEILVET", "length": 241 }, "evidence": [ { "id": "G3X7R6", "url": "https://omabrowser.org/oma/group/G3X7R6/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "Q9CWM2-1", "protein_name": "Cell division cycle-associated protein 4", "gene_name": "Cdca4", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MFARGLKRKYGDQEEGVEGFGTVPSYSLQRQSLLDMSLVKLQLCHMLVEPNLCRSVLIANTVRQIQEEMSQDGVWHGMAPQNVDRAPVERLVSTEILCRTVRGAEEEHPAPELEDAPLQNSVSELPIVGSAPGQRNPQSSLWEMDSPQENRGSFQKSLDQIFETLENKNSSSVEELFSDVDSSYYDLDTVLTGMMSGTKSSLCNGLEGFAAATPPPSSTCKSDLAELDHVVEILVET", "length": 237 }, "evidence": [ { "id": "G3X7R6", "url": "https://omabrowser.org/oma/group/G3X7R6/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" } ], "go_annotation": { "categories": [ { "name": "Molecular Function", "total": 1, "go_terms": [ { "name": "transcription coactivator activity", "id": "GO:0003713", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003713", "evidence": [ { "database": "UniProtKB", "id": "G3X7R6", "url": "https://www.uniprot.org/uniprotkb/G3X7R6" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 3, "go_terms": [ { "name": "nucleus", "id": "GO:0005634", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005634", "evidence": [ { "database": "UniProtKB", "id": "G3X7R6", "url": "https://www.uniprot.org/uniprotkb/G3X7R6" } ], "pmid": "" }, { "name": "nucleoplasm", "id": "GO:0005654", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005654", "evidence": [ { "database": "UniProtKB", "id": "G3X7R6", "url": "https://www.uniprot.org/uniprotkb/G3X7R6" } ], "pmid": "" }, { "name": "cytoplasm", "id": "GO:0005737", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005737", "evidence": [ { "database": "UniProtKB", "id": "G3X7R6", "url": "https://www.uniprot.org/uniprotkb/G3X7R6" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "G3X7R6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3X7R6" }, { "id": "PS51053", "database": "PROSITE", "url": "https://prosite.expasy.org/PS51053" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "SERTA", "eco_id": "ECO_0000259", "start_pos": 18, "end_pos": 65, "start_aa": "Asp", "end_aa": "Gly", "glycosite_overlap": [] } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "homologset.oma", "label": "OMA Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ], "tool_support": { "graph_view": "yes" } }, { "uniprot_canonical_ac": "G3X7S0-1", "uniprot_ac": "G3X7S0", "uniprot_id": "G3X7S0_BOVIN", "mass": { "chemical_mass": 46222.0, "monoisotopic_mass": 46222.0 }, "refseq": { "ac": "XP_024837971", "name": "zinc finger and BTB domain-containing protein 42 isoform X1", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_024837971" }, "gene_names": [ { "name": "ZBTB42", "type": "recommended", "evidence": [ { "id": "G3X7S0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3X7S0" } ] }, { "name": "ZBTB42", "type": "synonym", "evidence": [ { "id": "XP_024837971", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_024837971" } ] } ], "protein_names": [ { "name": "Zinc finger and BTB domain-containing protein 42", "type": "recommended", "evidence": [ { "id": "G3X7S0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3X7S0/entry#names_and_taxonomy" } ] }, { "name": "zinc finger and BTB domain-containing protein 42 isoform X1", "type": "synonym", "evidence": [ { "id": "XP_024837971", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_024837971" } ] } ], "function": [ { "annotation": "Transcriptional repressor. Specifically binds DNA and probably acts by recruiting chromatin remodeling multiprotein complexes.", "evidence": [ { "database": "UniProtKB", "id": "G3X7S0", "url": "https://www.uniprot.org/uniprotkb/G3X7S0#function" }, { "database": "UniProtKB", "id": "ARBA00056459", "url": "https://www.uniprot.org/uniprotkb/ARBA00056459#function" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Bos taurus", "taxid": 9913, "evidence": [ { "database": "UniProtKB", "id": "G3X7S0", "url": "https://www.uniprot.org/uniprotkb/G3X7S0" } ], "common_name": "Bovine", "glygen_name": "Bovine", "reference_species": "Bos taurus [9913]" } ], "gene": [ { "name": "ZBTB42", "url": "https://www.uniprot.org/uniprotkb/G3X7S0", "locus": { "chromosome": "21", "start_pos": 69264381, "end_pos": 69254501, "strand": "-", "evidence": [ { "database": "Ensembl Gene", "id": "ENSBTAG00000005038", "url": "https://www.ensembl.org/id/ENSBTAG00000005038" } ] } } ], "crossref": [ { "id": "ENSBTAG00000005038", "url": "https://bgee.org/?page=gene&gene_id=ENSBTAG00000005038", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "cd18956", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd18956", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "789062", "url": "https://www.ncbi.nlm.nih.gov/gene/789062", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR000210", "url": "https://www.ebi.ac.uk/interpro/entry/IPR000210", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR011333", "url": "https://www.ebi.ac.uk/interpro/entry/IPR011333", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR013087", "url": "https://www.ebi.ac.uk/interpro/entry/IPR013087", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR036236", "url": "https://www.ebi.ac.uk/interpro/entry/IPR036236", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "bta:789062", "url": "https://www.genome.jp/dbget-bin/www_bget?bta:789062", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "G3X7S0", "url": "https://www.orthodb.org/?gene=G3X7S0", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR24394", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR24394", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR24394:SF20", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR24394:SF20", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00096", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00096", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF00651", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00651", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF13894", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF13894", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "XP_024837971", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_024837971", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "G3X7S0", "url": "https://www.uniprot.org/uniprotkb/G3X7S0", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "G3X7S0-1", "url": "https://www.uniprot.org/uniprotkb/G3X7S0-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MEFPEHGGRLLGRLRQQRELGFLCDCTVLVGDARFPAHRAVLAACSVYFHLFYRDQPSGSRDTVRLNGDIVTAPAFGRLLDFMYEGRLDLRSLPVEDVLAAASYLHMYDIVKVCKNRLREKERALPPETPAPGAEPPVRPPGPLSAWAPAPCPASLKARLPPAGPKATRPPPAPGPLPWQTPGESDGALDLSLKPGPRRPPVRPPCALQTAPCRQKQPGAQPVVKEEPDSESEREDGSSSPRSAHSPLRPPGVTAAEPLVGGLGPLPVRGVGSGAPGPEAERGELEAALRPSGRLCLCPLCGKLFPGAHVLQPHLSAHFRERDGGRARLSPDGAAPTCPLCRKTFSCTYTLKRHERTHSGEKPYTCVQCGKSFQYSHNLSRHAVVHTREKPHACRWCERRFTQSGDLYRHVRKFHCGLVKSLLV", "length": 424, "header": "tr|G3X7S0-1|G3X7S0_BOVIN Isoform 1 of Zinc finger and BTB domain-containing protein 42 OS=Bos taurus OX=9913 GN=ZBTB42 PE=3 SV=3 CANONICAL=G3X7S0-1" }, "isoforms": [ { "isoform_ac": "G3X7S0-1", "url": "https://www.uniprot.org/uniprotkb/G3X7S0/entry", "sequence": { "sequence": "MEFPEHGGRLLGRLRQQRELGFLCDCTVLVGDARFPAHRAVLAACSVYFHLFYRDQPSGSRDTVRLNGDIVTAPAFGRLLDFMYEGRLDLRSLPVEDVLAAASYLHMYDIVKVCKNRLREKERALPPETPAPGAEPPVRPPGPLSAWAPAPCPASLKARLPPAGPKATRPPPAPGPLPWQTPGESDGALDLSLKPGPRRPPVRPPCALQTAPCRQKQPGAQPVVKEEPDSESEREDGSSSPRSAHSPLRPPGVTAAEPLVGGLGPLPVRGVGSGAPGPEAERGELEAALRPSGRLCLCPLCGKLFPGAHVLQPHLSAHFRERDGGRARLSPDGAAPTCPLCRKTFSCTYTLKRHERTHSGEKPYTCVQCGKSFQYSHNLSRHAVVHTREKPHACRWCERRFTQSGDLYRHVRKFHCGLVKSLLV", "length": 424, "header": "tr|G3X7S0-1|G3X7S0_BOVIN Isoform 1 of Zinc finger and BTB domain-containing protein 42 OS=Bos taurus OX=9913 GN=ZBTB42 PE=3 SV=3 CANONICAL=G3X7S0-1" }, "locus": { "chromosome": "21", "start_pos": 69265044, "end_pos": 69264381, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000044341.4", "url": "https://www.ensembl.org/id/ENSBTAT00000044341.4" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000041846.4", "url": "https://www.ensembl.org/id/ENSBTAP00000041846.4" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [ { "id": "bta:789062", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?bta:789062", "resource": "KEGG Pathway" } ], "orthologs": [], "go_annotation": { "categories": [ { "name": "Biological Process", "total": 4, "go_terms": [ { "name": "negative regulation of transcription by RNA polymerase II", "id": "GO:0000122", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000122", "evidence": [ { "database": "UniProtKB", "id": "G3X7S0", "url": "https://www.uniprot.org/uniprotkb/G3X7S0" } ], "pmid": "" }, { "name": "DNA-templated transcription", "id": "GO:0006351", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006351", "evidence": [ { "database": "UniProtKB", "id": "G3X7S0", "url": "https://www.uniprot.org/uniprotkb/G3X7S0" } ], "pmid": "" }, { "name": "regulation of transcription by RNA polymerase II", "id": "GO:0006357", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006357", "evidence": [ { "database": "UniProtKB", "id": "G3X7S0", "url": "https://www.uniprot.org/uniprotkb/G3X7S0" } ], "pmid": "" }, { "name": "muscle organ development", "id": "GO:0007517", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007517", "evidence": [ { "database": "UniProtKB", "id": "G3X7S0", "url": "https://www.uniprot.org/uniprotkb/G3X7S0" } ], "pmid": "" } ] }, { "name": "Molecular Function", "total": 3, "go_terms": [ { "name": "DNA binding", "id": "GO:0003677", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003677", "evidence": [ { "database": "UniProtKB", "id": "G3X7S0", "url": "https://www.uniprot.org/uniprotkb/G3X7S0" } ], "pmid": "" }, { "name": "zinc ion binding", "id": "GO:0008270", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008270", "evidence": [ { "database": "UniProtKB", "id": "G3X7S0", "url": "https://www.uniprot.org/uniprotkb/G3X7S0" } ], "pmid": "" }, { "name": "DNA-binding transcription factor activity, RNA polymerase II-specific", "id": "GO:0000981", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000981", "evidence": [ { "database": "UniProtKB", "id": "G3X7S0", "url": "https://www.uniprot.org/uniprotkb/G3X7S0" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 3, "go_terms": [ { "name": "nucleus", "id": "GO:0005634", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005634", "evidence": [ { "database": "UniProtKB", "id": "G3X7S0", "url": "https://www.uniprot.org/uniprotkb/G3X7S0" } ], "pmid": "" }, { "name": "nucleoplasm", "id": "GO:0005654", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005654", "evidence": [ { "database": "UniProtKB", "id": "G3X7S0", "url": "https://www.uniprot.org/uniprotkb/G3X7S0" } ], "pmid": "" }, { "name": "cytoplasm", "id": "GO:0005737", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005737", "evidence": [ { "database": "UniProtKB", "id": "G3X7S0", "url": "https://www.uniprot.org/uniprotkb/G3X7S0" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 378, "end_pos": 380, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "G3X7S0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3X7S0" }, { "id": "PS50097", "database": "PROSITE", "url": "https://prosite.expasy.org/PS50097" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "BTB", "eco_id": "ECO_0000259", "start_pos": 24, "end_pos": 92, "start_aa": "Cys", "end_aa": "Ser", "glycosite_overlap": [] }, { "evidence": [ { "id": "G3X7S0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3X7S0" }, { "id": "PS50157", "database": "PROSITE", "url": "https://prosite.expasy.org/PS50157" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "C2H2-type", "eco_id": "ECO_0000259", "start_pos": 296, "end_pos": 323, "start_aa": "Cys", "end_aa": "Asp", 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{ "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ], "tool_support": { "graph_view": "yes" } }, { "uniprot_canonical_ac": "G3X7U0-1", "uniprot_ac": "G3X7U0", "uniprot_id": "G3X7U0_BOVIN", "mass": { "chemical_mass": 52521.0, "monoisotopic_mass": 52521.0 }, "refseq": { "ac": "XP_002700080", "name": "NALCN channel auxiliary factor 2", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_002700080" }, "gene_names": [ { "name": "NALF2", "type": "recommended", "evidence": [ { "id": "G3X7U0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3X7U0" } ] }, { "name": "NALF2", "type": "synonym", "evidence": [ { "id": "XP_002700080", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_002700080" } ] } ], "protein_names": [ { "name": "NALCN channel auxiliary factor 2", "type": "synonym", "evidence": [ { "id": "XP_002700080", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_002700080" }, { "id": "G3X7U0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3X7U0/entry#names_and_taxonomy" } ] } ], "function": [], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Bos taurus", "taxid": 9913, "evidence": [ { "database": "UniProtKB", "id": "G3X7U0", "url": "https://www.uniprot.org/uniprotkb/G3X7U0" } ], "common_name": "Bovine", "glygen_name": "Bovine", "reference_species": "Bos taurus [9913]" } ], "gene": [ { "name": "NALF2", "url": "https://www.uniprot.org/uniprotkb/G3X7U0", "locus": { "chromosome": "X", "start_pos": 80933030, "end_pos": 80960400, "strand": "+", "evidence": [ { "database": "Ensembl Gene", "id": "ENSBTAG00000011310", "url": "https://www.ensembl.org/id/ENSBTAG00000011310" } ] } } ], "crossref": [ { "id": "G3X7U0", "url": "https://alphafold.ebi.ac.uk/entry/G3X7U0", "database": "AlphaFoldDB", "categories": [] }, { "id": "ENSBTAG00000011310", "url": "https://bgee.org/?page=gene&gene_id=ENSBTAG00000011310", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "613918", "url": "https://www.ncbi.nlm.nih.gov/gene/613918", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR055288", "url": "https://www.ebi.ac.uk/interpro/entry/IPR055288", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "bta:613918", "url": "https://www.genome.jp/dbget-bin/www_bget?bta:613918", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "QWVSCEA", "url": "https://omabrowser.org/oma/group/QWVSCEA/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "G3X7U0", "url": 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"MFRGAWMWPGKDAAALTICCCCCCWAPRPSDKPCADSERAQRWRLSLASLLFFTVLLADHLWLCAGARPRARELSSAMRPPWGAGRERQPVPPRAVLPLPPPPPPPGQPSAPPGTCGPRYSNLTKAAAAAGPGPDCGGVPEPTGLDAACTKLQSLQRLFEPTTPAPPLRPPDSPSRAPAEFPTAKKNLLKGHFRNFTLSFCDTYTVWDLLLGMDRPDSLDCSLDNLLGDLLAVVASPGSGAWEVCSNCIEAYQRLDRHAQEKYDEFDLVLHKYLQAEEYSIRSCTKGCKAVYKAWLCSEYFSVTQQECQRWVPCKQYCLEVQTRCPFILPDNEEMVYGGLPGFICTGLLDTSPKRPETKCCDVQWISCESEKKFKESEAPKTHHQQFHHSYFHHYHQQYHHYHPRHEPPGRLGHKPSLLPVSGGSRLSSSRIRLYILVLVLLHTMVSFSSSQSGGGPGLEALPALDEGLAREE", "length": 473, "header": "tr|G3X7U0-1|G3X7U0_BOVIN Isoform 1 of NALCN channel auxiliary factor 2 OS=Bos taurus OX=9913 GN=NALF2 PE=3 SV=1 CANONICAL=G3X7U0-1" }, "isoforms": [ { "isoform_ac": "G3X7U0-1", "url": "https://www.uniprot.org/uniprotkb/G3X7U0/entry", "sequence": { "sequence": "MFRGAWMWPGKDAAALTICCCCCCWAPRPSDKPCADSERAQRWRLSLASLLFFTVLLADHLWLCAGARPRARELSSAMRPPWGAGRERQPVPPRAVLPLPPPPPPPGQPSAPPGTCGPRYSNLTKAAAAAGPGPDCGGVPEPTGLDAACTKLQSLQRLFEPTTPAPPLRPPDSPSRAPAEFPTAKKNLLKGHFRNFTLSFCDTYTVWDLLLGMDRPDSLDCSLDNLLGDLLAVVASPGSGAWEVCSNCIEAYQRLDRHAQEKYDEFDLVLHKYLQAEEYSIRSCTKGCKAVYKAWLCSEYFSVTQQECQRWVPCKQYCLEVQTRCPFILPDNEEMVYGGLPGFICTGLLDTSPKRPETKCCDVQWISCESEKKFKESEAPKTHHQQFHHSYFHHYHQQYHHYHPRHEPPGRLGHKPSLLPVSGGSRLSSSRIRLYILVLVLLHTMVSFSSSQSGGGPGLEALPALDEGLAREE", "length": 473, "header": "tr|G3X7U0-1|G3X7U0_BOVIN Isoform 1 of NALCN channel auxiliary factor 2 OS=Bos taurus OX=9913 GN=NALF2 PE=3 SV=1 CANONICAL=G3X7U0-1" }, "locus": { "chromosome": "X", "start_pos": 80960201, "end_pos": 80934034, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000045942.5", "url": "https://www.ensembl.org/id/ENSBTAT00000045942.5" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000043288.3", "url": "https://www.ensembl.org/id/ENSBTAP00000043288.3" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [ { "id": "bta:613918", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?bta:613918", "resource": "KEGG Pathway" } ], "orthologs": [ { "uniprot_canonical_ac": "A0A1D5PZ05-1", "protein_name": "NALCN channel auxiliary factor 2", "gene_name": "FAM155B", "tax_id": 9031, "organism": "Gallus gallus", "sequence": { "sequence": "MIRGAWMYPRGGAGGGAVCCAPRRSDKPVADPERAQKWRLSLASLLFFTVLLSDHLWLCAGAKLRARERSGAGRPRGRTPRALQEPPAGSCEAFLGNLSRAPGPAPCPAARADLDSACARLHSLQRLLGSFAGVPLRSPPATALFSSPSSKRNFLQAYFRNFNLSFCDTYTIWDLLREMGGPDSLDCSVENLMVDLVAAAAGALGGEACSSCVQAYQRLDQHAQEKYEEFDLLLEKYLQSDEYSVRSCIRDCKAVYKAWLCSEYFNVTQQQCRHRIPCKQYCLEVQTRCPFVLPDNDELIYGGLPGFICTGLLESQLPEEEAKCCEVQWDSCDHPPDSSSDTSPKSTASESLHYHHHDPHLHHQRQNHYHLYHHHQYHHSPSLLPVSAGSRLGSSRIRLCVLVLMLLHTMVSFSSVHSGGGGLGPEALPSLDESVARDE", "length": 439 }, "evidence": [ { "id": "G3X7U0", "url": "https://omabrowser.org/oma/group/G3X7U0/", "database": "OMA" } ], "glygen_name": "Chicken", "common_name": "Chicken" }, { "uniprot_canonical_ac": "A2AWH2-1", "protein_name": "NALCN channel auxiliary factor 2", "gene_name": "nalf2", "tax_id": 7955, "organism": "Danio rerio", "sequence": { "sequence": "MITGAWRCGRKLDAELEICRVTEPIDKPCAESEKVQRWRMSLASLLFFTALLSDHLWLCAGGKLRSRDRTHRRTWNNASHDAQTGLRDEDCGVLLSNLTENGPDCVEADARRRAPLESACSTLYRQKSGSVSSSYSVTVPTVSPHAFLEYFRNFSLSFCDALTIADLLESMTSPDGLNCSLTHIIRDLFSGGPEDGDACSACVHAYTRLDQHAQEKYEEFDALTRKYMADDYSVRAQTHLCQVVYKAWLCAEYFPVPQRQCVRWLPCRHYCGEVTATCPFILPDNDRLLYAGSPSFLCAGFQEEYLSSQGPDCCDVRWSGCDSAVGAACALTHLPGSFSFHRRLSSGAMSCTNRLHGSKLKLCVLVLFLLHTFISITTLQHCSTGSLEAIVPLEEVPMREE", "length": 401 }, "evidence": [ { "id": "G3X7U0", "url": "https://omabrowser.org/oma/group/G3X7U0/", "database": "OMA" } ], "glygen_name": "Zebrafish", "common_name": "Zebrafish" }, { "uniprot_canonical_ac": "A2BDP1-1", "protein_name": "NALCN channel auxiliary factor 2", "gene_name": "Nalf2", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MFRGAWMWPGKDAAALTICCCCCCWAPRQSDKPCADSERAQRWRLSLASLLFFTVLLADHLWLCAGARPRARELSSAMRPPWGAGRERQPVPPRAVLPPPPPSPGEPSASSGTCGPRYSNLTKAAPAAGSGPVCNGVPEPTGLDAACTKLESLQRLFEPTTPAPPLRPPDSPSRAPEFPSAKKNLLKGHFRNFTLSFCDTYTVWDLLLGMDRPDSLDCSLDTLLGDLLAVVASPGSGTWEACSNCIEAYQRLDRHAQEKYDEFDLVLHKYLQAEEYSIRSCTKGCKAVYKAWLCSEYFSVTQQECQNWVPCKQYCLEVQTRCPFILPDNEEMVYGGLPGFICTGLMDTSPKRPETKCCDVQWVSCESEKKKFKDSEPPKTHHQQFHHSYFHHYHHQYHHYHPRHEPPSRVSNKPSLLPVSGGSRLSPSRIRLCVLVLILLHTVVSFSSSQSGGGLGLETLPALEEGLTQEE", "length": 471 }, "evidence": [ { "id": "G3X7U0", "url": "https://omabrowser.org/oma/group/G3X7U0/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "D4A4E6-1", "protein_name": "NALCN channel auxiliary factor 2", "gene_name": "Nalf2", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MFRGAWMWPGKDAAALTICCCCCCWAPRQSDKPCADSERAQRWRLSLASLLFFTVLLTDHLWLCAGARPRARELSSAMRPPWGAGRERQPVPRRAVLPLPPPSPGEPSASSGTCGPRYSNLTKAAPAAGSGPVCDGVPEPTGLDAACTKLESLQRLFEPTTPAPPLRPPDSPSRAPEFPSAKKNLLKGHFRNFTLSFCDTYTVWDLLLGMDRPDSLDCSLDTLLGDLLAVVASPGSGTWEACSNCIEAYQRLDRHAQEKYDEFDLVLHKYLQAEEYSIRSCTKGCKAVYKAWLCSEYFSVTQQECEHWVPCKQYCLEVQTRCPFILPDNEEMVYGGLPGFICTGLIDTSPKRPETKCCDVQWVSCESEKKKFKDSEPPKTHHQQFHHSYFHHYHQQYHHYHPRHEPPSRVSNKPSLLPVSGGSRLSPSRIRLCVLVLMLLHTVVSFSSSQGGGGLGLETLPALEEGLTQEE", "length": 471 }, "evidence": [ { "id": "G3X7U0", "url": "https://omabrowser.org/oma/group/G3X7U0/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "F1RSX6-1", "protein_name": "NALCN channel auxiliary factor 2", "gene_name": "NALF2", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MFRGAWMWPGKDAAALTICCCCCCWAPRPSDKPCADSERAQRWRLSLASLLFFTVLLADHLWLCAGARPRGRELSSAMRPPWGAGRERQPVPPRAVLPLPPPGQPSAPPGTCGPRHSNLTKAAPAAGPGPDCGGVPEPTGLDAACTKLQSLQRLFEPTTPAPPLRPPDSPSRAPAEFPTAKKNLLKGHFRNFTLSFCDTYTVWDLLLGMDRPDSLDCSLDTLLGDLLAVVASPGSGAWEVCSNCIEAYQRLDRHAQEKYDEFDLVLHKYLQAEEYSIRSCTKGCKAVYKAWLCSEYFSVTQQECQRWVPCKQYCLEVQTRCPFILPDNEEMVYGGLPGFICTGLLDTSPKRPETKCCDVQWVSCESEKKKFKETEAPKTHHQQFHHSYFHHYHQQYHHYHPRHDPPGRLSHKPSLLPVSGSSRLSPSRIRLYVLVLMLLHTMVSFSSSQGGGGPGLEALPALDEGLTREE", "length": 470 }, "evidence": [ { "id": "G3X7U0", "url": "https://omabrowser.org/oma/group/G3X7U0/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "O75949-1", "protein_name": "NALCN channel auxiliary factor 2", "gene_name": "NALF2", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": 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"total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 2 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ], "tool_support": { "graph_view": "yes" } }, { "uniprot_canonical_ac": "G5E500-1", "uniprot_ac": "G5E500", "uniprot_id": "G5E500_BOVIN", "mass": { "chemical_mass": 33109.0, "monoisotopic_mass": 33109.0 }, "refseq": {}, "gene_names": [ { "name": "MYADML2", "type": "recommended", "evidence": [ { "id": "G5E500", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G5E500" } ] } ], "protein_names": [ { "name": "Myeloid-associated differentiation marker-like protein 2", "type": "recommended", "evidence": [ { "id": "G5E500", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G5E500/entry#names_and_taxonomy" } ] } ], "function": [], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Bos taurus", "taxid": 9913, "evidence": [ { "database": "UniProtKB", "id": "G5E500", "url": "https://www.uniprot.org/uniprotkb/G5E500" } ], "common_name": "Bovine", "glygen_name": "Bovine", "reference_species": "Bos taurus [9913]" } ], "gene": [ { "name": "MYADML2", "url": "https://www.uniprot.org/uniprotkb/G5E500", "locus": { "chromosome": "19", "start_pos": 50956142, "end_pos": 50953006, "strand": "-", "evidence": [ { "database": "Ensembl Gene", "id": "ENSBTAG00000000044", "url": "https://www.ensembl.org/id/ENSBTAG00000000044" } ] } } ], "crossref": [ { "id": "G5E500", "url": "https://alphafold.ebi.ac.uk/entry/G5E500", "database": "AlphaFoldDB", "categories": [] }, { "id": "ENSBTAG00000000044", "url": "https://bgee.org/?page=gene&gene_id=ENSBTAG00000000044", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "IPR008253", "url": "https://www.ebi.ac.uk/interpro/entry/IPR008253", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR047123", "url": "https://www.ebi.ac.uk/interpro/entry/IPR047123", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "TGGPYLN", "url": "https://omabrowser.org/oma/group/TGGPYLN/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "G5E500", "url": "https://www.orthodb.org/?gene=G5E500", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR17068", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR17068", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR17068:SF5", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR17068:SF5", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF01284", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF01284", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "G5E500", "url": "https://www.uniprot.org/uniprotkb/G5E500", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "G5E500-1", "url": "https://www.uniprot.org/uniprotkb/G5E500-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MGSTMEPPGGGYLHLGAVTSPVGTARVLQLVFGCTTFSLVAHRGGFSGVQGTFCVAAWGFCFALSVLVVACEFTRLHGCLRLSWGNFTAAFAMLATLLSATAAVIYPLYFTRLECPPEPEGCTARNFRLAASVFAGLLFLAYATEVALTRARPGQVASYMATVSGLLKIVQAFVACIIFGALVHDSRYGRYVATQWCVAVYSLCFLATVVVVILSVLGHTGGLGCPFDRMVVVYTFLAVLLYLSAAVIWPVFCFDPKYGEPGRPPDCPRGSCPWDSQLVVATFTYINLLLYVADLAYSQRIRFVPTF", "length": 307, "header": "tr|G5E500-1|G5E500_BOVIN Isoform 1 of Myeloid-associated differentiation marker-like protein 2 OS=Bos taurus OX=9913 GN=MYADML2 PE=3 SV=1 CANONICAL=G5E500-1" }, "isoforms": [ { "isoform_ac": "G5E500-1", "url": "https://www.uniprot.org/uniprotkb/G5E500/entry", "sequence": { "sequence": "MGSTMEPPGGGYLHLGAVTSPVGTARVLQLVFGCTTFSLVAHRGGFSGVQGTFCVAAWGFCFALSVLVVACEFTRLHGCLRLSWGNFTAAFAMLATLLSATAAVIYPLYFTRLECPPEPEGCTARNFRLAASVFAGLLFLAYATEVALTRARPGQVASYMATVSGLLKIVQAFVACIIFGALVHDSRYGRYVATQWCVAVYSLCFLATVVVVILSVLGHTGGLGCPFDRMVVVYTFLAVLLYLSAAVIWPVFCFDPKYGEPGRPPDCPRGSCPWDSQLVVATFTYINLLLYVADLAYSQRIRFVPTF", "length": 307, "header": "tr|G5E500-1|G5E500_BOVIN Isoform 1 of Myeloid-associated differentiation marker-like protein 2 OS=Bos taurus OX=9913 GN=MYADML2 PE=3 SV=1 CANONICAL=G5E500-1" }, "locus": { "chromosome": "19", "start_pos": 50954022, "end_pos": 50953102, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000000049.6", "url": "https://www.ensembl.org/id/ENSBTAT00000000049.6" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000000049.5", "url": "https://www.ensembl.org/id/ENSBTAP00000000049.5" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [], "orthologs": [ { "uniprot_canonical_ac": "A0A8V1AP18-1", "protein_name": "Myeloid-associated differentiation marker-like protein 2", "gene_name": "MYADML2", "tax_id": 9031, "organism": "Gallus gallus", "sequence": { "sequence": "MMESTGGPYLNTAAVTSPVGIVRLLQMMFGCTTFSLVAHQGGFSAAYGTFCMFVWTFCFSVTVFIITCEFTHLHSCLSISWGNFTAAFAMLATLMSVTAAVIYPLYFVQLGCYPITCEVRDFRIAASIFAGLVFVVYGAEVFLTRAKPGQVTSYMATVSGLLKIVQAFVACIIFGALVNDSQYSKYVATQWCVAVYSFCFMVTVVVVAFSVTGKTAQLCFPFERSVVVYTFGAVLLYVSAAVIWPVFCFDSKYGSPQRPSACAKGRCPWDSQLVVAIFTYVNLLLYVVDLAYSQRIRFVSHI", "length": 302 }, "evidence": [ { "id": "G5E500", "url": "https://omabrowser.org/oma/group/G5E500/", "database": "OMA" } ], "glygen_name": "Chicken", "common_name": "Chicken" }, { "uniprot_canonical_ac": "F1QNB6-1", "protein_name": "Myeloid-associated differentiation marker-like protein 2", "gene_name": "myadml2", "tax_id": 7955, "organism": "Danio rerio", "sequence": { "sequence": "MDPQGGHYLNKSAVLSCLGAARMCQLLLGCTTMALVAHSAGFSATYGTFCMFVWCFCFAVTLLVFTLDVTRLHGCMPISWDNFTVAFAMLATLMYVTASVVYPVYFLRSDCPSQGCEVRNYRIAVTVCSSVCCFAYGAEVFITRAKPGHVVGYMATVSGLLKVVQAFIACIIFGALHNDSQYNRHIPTQYCVVVYSLCFAVTVVVVALTVSGRTSSLRFPFDRFVVIYTFLAVLLYLSAAVIWPVFSFDKKYGAPGRPDDCPKGKCPWDSKLVIAVFTCANLVLYFTDLVYSQRIRFVLSSAA", "length": 303 }, "evidence": [ { "id": "G5E500", "url": "https://omabrowser.org/oma/group/G5E500/", "database": "OMA" } ], "glygen_name": "Zebrafish", "common_name": "Zebrafish" } ], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 2, "go_terms": [ { "name": "cytoplasm", "id": "GO:0005737", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005737", "evidence": [ { "database": "UniProtKB", "id": "G5E500", "url": "https://www.uniprot.org/uniprotkb/G5E500" } ], "pmid": "" }, { "name": "membrane", "id": "GO:0016020", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016020", "evidence": [ { "database": "UniProtKB", "id": "G5E500", "url": "https://www.uniprot.org/uniprotkb/G5E500" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 86, "end_pos": 88, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [ { "pdb_id": "AF-G5E500-F1", "pdb_chain": "global", "start_pos": 1, "end_pos": 307, "overlap": "1.0", "method": "AlphaFold", "type": "alphafold", "resolution": -1.0, "url": "https://data.glygen.org/ln2downloads/pdb/current/AF-G5E500-F1.pdb", "url_external": "https://alphafold.ebi.ac.uk/entry/G5E500" } ], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "G5E500", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G5E500" }, { "id": "PS51225", "database": "PROSITE", "url": "https://prosite.expasy.org/PS51225" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "MARVEL", "eco_id": "ECO_0000259", "start_pos": 17, "end_pos": 154, "start_aa": "Ala", "end_aa": "Gly", "glycosite_overlap": [] } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "homologset.oma", "label": "OMA Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 86, "end_pos": 88 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": 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"table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ], "tool_support": { "graph_view": "yes" } }, { "uniprot_canonical_ac": "G5E547-1", "uniprot_ac": "G5E547", "uniprot_id": "G5E547_BOVIN", "mass": { "chemical_mass": 41494.0, "monoisotopic_mass": 41494.0 }, "refseq": { "ac": "XP_010820487", "name": "synapse-associated protein 1 isoform X1", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_010820487" }, "gene_names": [ { "name": "SYAP1", "type": "recommended", "evidence": [ { "id": "G5E547", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G5E547" } ] }, { "name": "SYAP1", "type": "synonym", "evidence": [ { "id": "XP_010820487", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_010820487" } ] } ], "protein_names": [ { "name": "Synapse-associated protein 1", "type": "recommended", "evidence": [ { "id": "G5E547", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G5E547/entry#names_and_taxonomy" } ] }, { "name": "BSD domain-containing signal transducer and Akt interactor protein", "type": "synonym", "evidence": [ { "id": "G5E547", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G5E547/entry#names_and_taxonomy" } ] }, { "name": "synapse-associated protein 1 isoform X1", "type": "synonym", "evidence": [ { "id": "XP_010820487", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_010820487" } ] } ], "function": [ { "annotation": "Plays a role in adipocyte differentiation by promoting mTORC2-mediated phosphorylation of AKT1 at 'Ser-473' after growth factor stimulation.", "evidence": [ { "database": "UniProtKB", "id": "G5E547", "url": "https://www.uniprot.org/uniprotkb/G5E547#function" }, { "database": "UniProtKB", "id": "ARBA00058614", "url": "https://www.uniprot.org/uniprotkb/ARBA00058614#function" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Bos taurus", "taxid": 9913, "evidence": [ { "database": "UniProtKB", "id": "G5E547", "url": "https://www.uniprot.org/uniprotkb/G5E547" } ], "common_name": "Bovine", "glygen_name": "Bovine", "reference_species": "Bos taurus [9913]" } ], "gene": [ { "name": "SYAP1", "url": "https://www.uniprot.org/uniprotkb/G5E547", "locus": { "chromosome": "X", "start_pos": 126782220, "end_pos": 126798177, "strand": "+", "evidence": [ { "database": "Ensembl Gene", "id": "ENSBTAG00000003316", "url": "https://www.ensembl.org/id/ENSBTAG00000003316" } ] } } ], "crossref": [ { "id": "G5E547", "url": "https://alphafold.ebi.ac.uk/entry/G5E547", "database": "AlphaFoldDB", "categories": [] }, { "id": "509355", "url": "https://www.ncbi.nlm.nih.gov/gene/509355", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR005607", "url": "https://www.ebi.ac.uk/interpro/entry/IPR005607", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR035925", "url": "https://www.ebi.ac.uk/interpro/entry/IPR035925", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR051494", "url": "https://www.ebi.ac.uk/interpro/entry/IPR051494", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "PTHR16019", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR16019", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR16019:SF6", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR16019:SF6", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF03909", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF03909", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "XP_010820487", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_010820487", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "G5E547", "url": "https://www.uniprot.org/uniprotkb/G5E547", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "G5E547-1", "url": "https://www.uniprot.org/uniprotkb/G5E547-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MFRSLSSWFGLEQPAAGGRQSQGDGQPRGHAPPDQRSEAVAESVEGEPQLAGNQELLHQAKGLGNYLFNFATAATKKITESVAETAQTIKKSVEEGKIDDIIDKTFIGDFHKEQKKFVEEQNTKKSEVAVPPWVDSNDEETIQQQILALSADKRNFLRDPPAGVQFNFDFDQMYPVALVMLQEDELLSRMRFDLVPKLVKEDVFWRNYFYRVSLIKQSAQLTALAAQQQAAGKEEKNHGRQNELPLTEAVRPKTPPVVIKSQLKTQEGSCIAFQDEEEISTSPCVSEFVSDAFDSCNLDQEDLRKEMEQLVLDKKEEGTVALEEDSVDWEKELQQELQEYEVVAESEKRDENWDKEIEEMLKEEN", "length": 365, "header": "tr|G5E547-1|G5E547_BOVIN Isoform 1 of Synapse-associated protein 1 OS=Bos taurus OX=9913 GN=SYAP1 PE=4 SV=1 CANONICAL=G5E547-1" }, "isoforms": [ { "isoform_ac": "G5E547-1", "url": "https://www.uniprot.org/uniprotkb/G5E547/entry", "sequence": { "sequence": "MFRSLSSWFGLEQPAAGGRQSQGDGQPRGHAPPDQRSEAVAESVEGEPQLAGNQELLHQAKGLGNYLFNFATAATKKITESVAETAQTIKKSVEEGKIDDIIDKTFIGDFHKEQKKFVEEQNTKKSEVAVPPWVDSNDEETIQQQILALSADKRNFLRDPPAGVQFNFDFDQMYPVALVMLQEDELLSRMRFDLVPKLVKEDVFWRNYFYRVSLIKQSAQLTALAAQQQAAGKEEKNHGRQNELPLTEAVRPKTPPVVIKSQLKTQEGSCIAFQDEEEISTSPCVSEFVSDAFDSCNLDQEDLRKEMEQLVLDKKEEGTVALEEDSVDWEKELQQELQEYEVVAESEKRDENWDKEIEEMLKEEN", "length": 365, "header": "tr|G5E547-1|G5E547_BOVIN Isoform 1 of Synapse-associated protein 1 OS=Bos taurus OX=9913 GN=SYAP1 PE=4 SV=1 CANONICAL=G5E547-1" }, "locus": { "chromosome": "X", "start_pos": 126798005, "end_pos": 126783051, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000004296.7", "url": "https://www.ensembl.org/id/ENSBTAT00000004296.7" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000004296.6", "url": "https://www.ensembl.org/id/ENSBTAP00000004296.6" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [], "orthologs": [], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 10, "go_terms": [ { "name": "nucleoplasm", "id": "GO:0005654", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005654", "evidence": [ { "database": "UniProtKB", "id": "G5E547", "url": "https://www.uniprot.org/uniprotkb/G5E547" } ], "pmid": "" }, { "name": "Golgi apparatus", "id": "GO:0005794", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005794", "evidence": [ { "database": "UniProtKB", "id": "G5E547", "url": "https://www.uniprot.org/uniprotkb/G5E547" } ], "pmid": "" }, { "name": "cytosol", "id": "GO:0005829", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005829", "evidence": [ { "database": "UniProtKB", "id": "G5E547", "url": "https://www.uniprot.org/uniprotkb/G5E547" } ], "pmid": "" }, { "name": "dendrite", "id": "GO:0030425", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030425", "evidence": [ { "database": "UniProtKB", "id": "G5E547", "url": "https://www.uniprot.org/uniprotkb/G5E547" } ], "pmid": "" }, { "name": "growth cone", "id": "GO:0030426", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030426", "evidence": [ { "database": "UniProtKB", "id": "G5E547", "url": "https://www.uniprot.org/uniprotkb/G5E547" } ], "pmid": "" }, { "name": "perikaryon", "id": "GO:0043204", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0043204", "evidence": [ { "database": "UniProtKB", "id": "G5E547", "url": "https://www.uniprot.org/uniprotkb/G5E547" } ], "pmid": "" }, { "name": "postsynaptic membrane", "id": "GO:0045211", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0045211", "evidence": [ { "database": "UniProtKB", "id": "G5E547", "url": "https://www.uniprot.org/uniprotkb/G5E547" } ], "pmid": "" }, { "name": "perinuclear region of cytoplasm", "id": "GO:0048471", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0048471", "evidence": [ { "database": "UniProtKB", "id": "G5E547", "url": "https://www.uniprot.org/uniprotkb/G5E547" } ], "pmid": "" }, { "name": "cytoplasmic side of plasma membrane", "id": "GO:0009898", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0009898", "evidence": [ { "database": "UniProtKB", "id": "G5E547", "url": "https://www.uniprot.org/uniprotkb/G5E547" } ], "pmid": "" }, { "name": "presynaptic membrane", "id": "GO:0042734", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0042734", "evidence": [ { "database": "UniProtKB", "id": "G5E547", "url": "https://www.uniprot.org/uniprotkb/G5E547" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 6, "go_terms": [ { "name": "cellular response to insulin stimulus", "id": "GO:0032869", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0032869", "evidence": [ { "database": "UniProtKB", "id": "G5E547", "url": "https://www.uniprot.org/uniprotkb/G5E547" } ], "pmid": "" }, { "name": "positive regulation of fat cell differentiation", "id": "GO:0045600", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0045600", "evidence": [ { "database": "UniProtKB", "id": "G5E547", "url": "https://www.uniprot.org/uniprotkb/G5E547" } ], "pmid": "" }, { "name": "cellular response to epidermal growth factor stimulus", "id": "GO:0071364", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0071364", "evidence": [ { "database": "UniProtKB", "id": "G5E547", "url": "https://www.uniprot.org/uniprotkb/G5E547" } ], "pmid": "" }, { "name": "cellular response to platelet-derived growth factor stimulus", "id": "GO:0036120", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0036120", "evidence": [ { "database": "UniProtKB", "id": "G5E547", "url": "https://www.uniprot.org/uniprotkb/G5E547" } ], "pmid": "" }, { "name": "TORC2 signaling", "id": "GO:0038203", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0038203", "evidence": [ { "database": "UniProtKB", "id": "G5E547", "url": "https://www.uniprot.org/uniprotkb/G5E547" } ], "pmid": "" }, { "name": "cellular response to insulin-like growth factor stimulus", "id": "GO:1990314", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:1990314", "evidence": [ { "database": "UniProtKB", "id": "G5E547", "url": "https://www.uniprot.org/uniprotkb/G5E547" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "G5E547", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G5E547" }, { "id": "PS50858", "database": "PROSITE", "url": "https://prosite.expasy.org/PS50858" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "BSD", "eco_id": "ECO_0000259", "start_pos": 164, "end_pos": 216, "start_aa": "Val", "end_aa": "Lys", "glycosite_overlap": [] } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ], "tool_support": { "graph_view": "yes" } }, { "uniprot_canonical_ac": "G5E573-1", "uniprot_ac": "G5E573", "uniprot_id": "G5E573_BOVIN", "mass": { "chemical_mass": 77608.0, "monoisotopic_mass": 77608.0 }, "refseq": { "ac": "NP_001193559", "name": "vertnin", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001193559" }, "gene_names": [ { "name": "VRTN", "type": "recommended", "evidence": [ { "id": "G5E573", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G5E573" } ] }, { "name": "VRTN", "type": "synonym", "evidence": [ { "id": "NP_001193559", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001193559" } ] } ], "protein_names": [ { "name": "Vertnin", "type": "recommended", "evidence": [ { "id": "G5E573", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G5E573/entry#names_and_taxonomy" } ] }, { "name": "vertebrae development homolog (pig)", "type": "synonym", "evidence": [ { "id": "NP_001193559", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001193559" } ] }, { "name": "vertnin", "type": "synonym", "evidence": [ { "id": "NP_001193559", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001193559" } ] } ], "function": [], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Bos taurus", "taxid": 9913, "evidence": [ { "database": "UniProtKB", "id": "G5E573", "url": "https://www.uniprot.org/uniprotkb/G5E573" } ], "common_name": "Bovine", "glygen_name": "Bovine", "reference_species": "Bos taurus [9913]" } ], "gene": [ { "name": "VRTN", "url": "https://www.uniprot.org/uniprotkb/G5E573", "locus": { "chromosome": "10", "start_pos": 85682201, "end_pos": 85672636, "strand": "-", "evidence": [ { "database": "Ensembl Gene", "id": "ENSBTAG00000005774", "url": "https://www.ensembl.org/id/ENSBTAG00000005774" } ] } } ], "crossref": [ { "id": "ENSBTAG00000005774", "url": "https://bgee.org/?page=gene&gene_id=ENSBTAG00000005774", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "cd22791", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd22791", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "528708", "url": "https://www.ncbi.nlm.nih.gov/gene/528708", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR038822", "url": "https://www.ebi.ac.uk/interpro/entry/IPR038822", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR047273", "url": "https://www.ebi.ac.uk/interpro/entry/IPR047273", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR060296", "url": "https://www.ebi.ac.uk/interpro/entry/IPR060296", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "bta:528708", "url": "https://www.genome.jp/dbget-bin/www_bget?bta:528708", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "RRCDHVP", "url": "https://omabrowser.org/oma/group/RRCDHVP/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "G5E573", "url": "https://www.orthodb.org/?gene=G5E573", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR16081", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR16081", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR16081:SF0", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR16081:SF0", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF28388", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF28388", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "NP_001193559", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001193559", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "G5E573", "url": "https://www.uniprot.org/uniprotkb/G5E573", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "G5E573-1", "url": "https://www.uniprot.org/uniprotkb/G5E573-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MTSREQLVQHVLQELQEAVESEGLEGLVGAALEAKQVLSSFALPTRRGGGPGPQVLEVDSVALSLYPEDAPRNMLPLVCQGEGSLLFEAASLLLWGDAGLSLELRARTVVEMLLHRHYYLQGMIDSKVMLQAVRYSLRSEESPEMTSLPSATLEAIFDADVKATCFPSSFSNVWHLYALASVVQRNIYSIYPLRNLKIRPYFNRVIRPRRCDHTPATLHIMWAGQPLSGHLFRHQYFAPVVGLEEVEAESAHPGPAPLPPPAKTLELLNREPGLSYSHLGEHSSVTKSTFYRWRRQSQEHRQKVATRFSAKHFLQDSFHRGGVVPLQQFLQRFPEISRSTYYAWKHELVGSGACQALTPTEELTKLPERQVAEGLGCSSTAASSPGVVFMQRAKLYLEHCIALNTLVPYRCFKRRFPGISRSTYYNWRRKALRRNPSFKPVPALLESGPPQPVPVGEKALLPWKGGEVGEGAAKATGGGPPAPRAFLPLRVPLSRWQRRLRRAARKQVLGGHLPFCRFRLRYPSLSPSSFWVWKSLARSWPGSLSKLHIPAPTLGRGSRKEAEEKEAGRNVIAAVAPPEGTWPMAASPGQDPRKATGGPSREGALQEGPTAQGRPPSGSLSSHPVVTAAAAGGRDGQVLVMDMLATTKFKAQAKLFLQKRFQSKSFPSYKEFSTLFPLTARSTYYMWKRALYDGLTLVDG", "length": 700, "header": "tr|G5E573-1|G5E573_BOVIN Isoform 1 of Vertnin OS=Bos taurus OX=9913 GN=VRTN PE=3 SV=1 CANONICAL=G5E573-1" }, "isoforms": [ { "isoform_ac": "G5E573-1", "url": "https://www.uniprot.org/uniprotkb/G5E573/entry", "sequence": { "sequence": "MTSREQLVQHVLQELQEAVESEGLEGLVGAALEAKQVLSSFALPTRRGGGPGPQVLEVDSVALSLYPEDAPRNMLPLVCQGEGSLLFEAASLLLWGDAGLSLELRARTVVEMLLHRHYYLQGMIDSKVMLQAVRYSLRSEESPEMTSLPSATLEAIFDADVKATCFPSSFSNVWHLYALASVVQRNIYSIYPLRNLKIRPYFNRVIRPRRCDHTPATLHIMWAGQPLSGHLFRHQYFAPVVGLEEVEAESAHPGPAPLPPPAKTLELLNREPGLSYSHLGEHSSVTKSTFYRWRRQSQEHRQKVATRFSAKHFLQDSFHRGGVVPLQQFLQRFPEISRSTYYAWKHELVGSGACQALTPTEELTKLPERQVAEGLGCSSTAASSPGVVFMQRAKLYLEHCIALNTLVPYRCFKRRFPGISRSTYYNWRRKALRRNPSFKPVPALLESGPPQPVPVGEKALLPWKGGEVGEGAAKATGGGPPAPRAFLPLRVPLSRWQRRLRRAARKQVLGGHLPFCRFRLRYPSLSPSSFWVWKSLARSWPGSLSKLHIPAPTLGRGSRKEAEEKEAGRNVIAAVAPPEGTWPMAASPGQDPRKATGGPSREGALQEGPTAQGRPPSGSLSSHPVVTAAAAGGRDGQVLVMDMLATTKFKAQAKLFLQKRFQSKSFPSYKEFSTLFPLTARSTYYMWKRALYDGLTLVDG", "length": 700, "header": "tr|G5E573-1|G5E573_BOVIN Isoform 1 of Vertnin OS=Bos taurus OX=9913 GN=VRTN PE=3 SV=1 CANONICAL=G5E573-1" }, "locus": { "chromosome": "10", "start_pos": 85681185, "end_pos": 85679086, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000124194.1", "url": "https://www.ensembl.org/id/ENSBTAT00000124194.1" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000096181.1", "url": "https://www.ensembl.org/id/ENSBTAP00000096181.1" } ] } } ], "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "other", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 610, "start_aa": "Thr", "end_pos": 610, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr610", "evidence": [ { "id": "", "database": "GlyGen", "url": "https://data.glygen.org/" } ], "filter_code": "000000000000000010000.00000000001000.0.01000" } ], "phosphorylation": [], "glycation": [], "keywords": [ "glycoprotein", "glycoprotein_predicted" ], "publication": [], "pathway": [ { "id": "bta:528708", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?bta:528708", "resource": "KEGG Pathway" } ], "orthologs": [ { "uniprot_canonical_ac": "A0A8V0XUZ0-1", "protein_name": "Vertnin", "gene_name": "VRTN", "tax_id": 9031, "organism": "Gallus gallus", "sequence": { "sequence": "MGLQHGPAALPGAAGLSLLDSCWWERIGAGLGNLHYWMPPTHQFRMIQRHQLVQSVLQELQEATECFGLEGLASAALEAERTLSSFSLPGYCRRQFQEELEVDRVARSLYPEDAPSNMLPLVCKGEGNRLFEAASVLLWGNPSLSLELQVRTVVEMLLHKQYYLNGMIDSKVMLQAARYSLCTEETPEMTSLPMAILEAIFDADIKATCFPGTFANMWHVYALASVLQCNIYSIYPMSNLKIRPYFNRLIRPRKCGPRTSTLHIMWSGQQLSRQVFKAQYFVAVVGLEELEPTIPSSEPPVQPMKTLELLNSDPQLTYSNLRDRYSITKSTFYRWKRQSREHRQKAAARFAAKHFLQSCFQEGNVVPLQHFRQMFPEISRSTYYAWKHEMQSVVNGDASALAEAHGLQELHREVPKKADVSEPTKAEVSIRPPSPSLDPVQAGIFMRGAKSYLEKCISMNTLVPYRCFKHSFPGISRSTYYNWRRKAIKENPNFKPPQPPLNNQKPLAIEKPLLQLKPSSLPARKKLNGDQPAARSLLQLKPSLCWRKRLRDVARRQVQQWRLPFSKFCLRYPTLSSTTYWFWKGSSRASGQRHLPSSKRPLNRVTSLAPQRSEPSVKPQLHTEVATKHLDKSAPTTPYNATISGYPVSERANSQMFVMDVIATTQFKAQAKLFLQQRFESKTFPTYKEFSARFPLTARSTYYMWKRALHDGLTLVDA", "length": 718 }, "evidence": [ { "id": "G5E573", "url": "https://omabrowser.org/oma/group/G5E573/", "database": "OMA" } ], "glygen_name": "Chicken", "common_name": "Chicken" }, { "uniprot_canonical_ac": "I3LVD7-1", "protein_name": "Vertnin", "gene_name": "VRTN", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MTSREQLVLQVLQELQEAVESEGLEGLVGAALEAKQVLSSFALPTCREGGPGPQVLEVDSVALSLYPEDAPRNMLPLVCKGEGSLLFEAASMLLWGDSGLSLELRARTVVEMLLHRHYYLQGMIDSKVMLQAVRYSLCSEESPEMTSLPSATLEAIFDADVKATCFPSSFSNVWHLYALASVLQRNIYSIYPMRNLKIRPYFNRVIRPRRCDHMPATLHIMWAGQPLTNHLFRHQYFAPVVGLEEVEAESATTSLAPTPPALAPLPPPAKTLELLSQDPGLSYSYLCERYSVTKSTFYRWRRQSQEHRQKVATRFSAKHFLQDSFHRGGVVPLQQFLQRFPEISRSTYYAWKHELLGSGTCQALDPMEELEKLTEEQVAEGLGCSSPAVSSPGMVLMQRAKLYLEHCISLNTLVPYRCFKRRFPGISRSTYYNWRRKALRRNPSFKPAPVLSVAGATQPASVGEKALLPWEGEVGEEAGKATGGGQPAPREFLPLRMPLSRWQRRLRREARKQVLSGHLPFCRFRLRYPSLSPSTFWVWKSLARGWPRSLSKLHIQAPTLGKGGIQEVEEKQEKEAGRNVTAAMAPPAGTLQMTASPGEDPGAALGGPSREGALQEGAMAKGRPMVAAAGGRDGQVLVMDMLATTKFKAQAKLFLQKRFQSKSFPSYKEFSALFPTARSTYYMWKRALYDGLTLVDG", "length": 697 }, "evidence": [ { "id": "G5E573", "url": "https://omabrowser.org/oma/group/G5E573/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "M0RCR3-1", "protein_name": "Vertnin", "gene_name": "Vrtn", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MTSRDQLVQQVLRNLQEAVESEGLEGLISAALEAKQVLASFSLPICQKGGPGAQVLEVDSVALSLYPEDAPRNMLPLVCKGEGSLLFEAASMLLWGHTGLSLELRARTVVEMLLHRHYYLQGMIDSKVMLQAVRYSLCSEESPEMTNLSFATLEAIFDADVRATCFPTSFSNVWHLYALASILERNIYSIYPMRNVRIRPYFNRVIMPRRSTHVTSMLHIMWAGQPLTSHLFRHQYFAPVVGLEEVEADGTASLDPAPPNLGPLLPPAKTLELLNREPGLSYSHLCDRTSITKSTFYRWRRQTQEHRQKVATRFSAKHFLQDSYHRGGFVPLQQFLQRFPEISRSTYYAWKHELLGSGANSALVPATPSREAVAVPEVERPPGKMAAEELGCSPLTAAISSPTSLILMQRAKSYLEHCISLNKLVPYRCFKCRFPGISRSTYYNWRRKALRRTPSFKLSPGLETTESLQPTDVGEESLHSLKSEVGEEGAGKAVGEAPLTSRGFTSPRMPLSRWQRRIRRAARKQVQSGRLPFCRFRLRYPSLLPSTFWVWKSLSRGRPRMQAPSLSQRKQKLEERQKPEERQKPEEWQKPEERQKPEEWQKPEERQKPEERQKPVEWQDVEAVRKVTPVVVPSVETLPVAASPEDAPEIAPGGPSREGIVQEAAVVQGQPHSGSLPSQTMVMAPGGSDGQVLVMDVLSATRFKAQAKLFLQKRFQSKTFPSYKEFQALFPLTARSTYYMWKRALYEGLTLVDG", "length": 754 }, "evidence": [ { "id": "G5E573", "url": "https://omabrowser.org/oma/group/G5E573/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": 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"glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q9H8Y1-1", "protein_name": "Vertnin", "gene_name": "VRTN", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MTSRNQLVQKVLQELQEAVECEGLEGLIGASLEAKQVLSSFTLPTCREGGPGLQVLEVDSVALSLYPEDAPRNMLPLVCKGEGSLLFEAASMLLWGDAGLSLELRARTVVEMLLHRHYYLQGMIDSKVMLQAVRYSLCSEESPEMTSLPPATLEAIFDADVKASCFPSSFSNVWHLYALASVLQRNIYSIYPMRNLKIRPYFNRVIRPRRCDHVPSTLHIMWAGQPLTSHFFRHQYFAPVVGLEEVEAEGAPGVAPALPALAPLSSPAKTLELLNREPGLSYSHLCERYSVTKSTFYRWRRQSQEHRQKVAARFSAKHFLQDSFHRGGVVPLQQFLQRFPEISRSTYYAWKHELLGSGTCPALPPREVLGMEELEKLPEEQVAEEELECSALAVSSPGMVLMQRAKLYLEHCISLNTLVPYRCFKRRFPGISRSTYYNWRRKALRRNPSFKPAPALSAAGTPQLASVGEGAVIPWKSEAEEGAGNATGEDPPAPGELLPLRMPLSRWQRRLRRAARRQVLSGHLPFCRFRLRYPSLSPSAFWVWKSLARGWPRGLSKLQVPVPTLGKGGQEAEEKQEKEAGRDVTAVMAPPVGASSEDVEGGPSREGALQEGATAQGQPHSGPLLSQPVVAAAGGRDGRMLVMDMIATTKFKAQAKLFLQKRFQSKSFPSYKEFSALFPLTARSTYYMWKRALYDGLTLVDG", "length": 702 }, "evidence": [ { "id": "G5E573", "url": "https://omabrowser.org/oma/group/G5E573/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" } ], "go_annotation": { "categories": [ { "name": "Biological Process", "total": 1, "go_terms": [ { "name": "regulation of transcription by RNA polymerase II", "id": "GO:0006357", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006357", "evidence": [ { "database": "UniProtKB", "id": "G5E573", "url": "https://www.uniprot.org/uniprotkb/G5E573" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 1, "go_terms": [ { "name": "chromatin", "id": "GO:0000785", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000785", "evidence": [ { "database": "UniProtKB", "id": "G5E573", "url": "https://www.uniprot.org/uniprotkb/G5E573" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "G5E573", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G5E573" }, { "id": "PF28388", "database": "Pfam", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF28388" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "Vertnin middle", "eco_id": "ECO_0000259", "start_pos": 310, "end_pos": 347, "start_aa": "Ala", "end_aa": "Glu", "glycosite_overlap": [] } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "homologset.oma", "label": "OMA Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [ 610 ], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 1 }, { "field": "total_sites", "count": 1 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 1 }, { "field": 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"glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 1 }, { "field": "total_sites", "count": 1 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 1 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "exact_sites", "count": 1 }, { "field": "exact_o_linked_sites", "count": 1 }, { "field": "fuzzy_sites", "count": 0 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_pos", "start_aa", "end_pos", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ], "tool_support": { "graph_view": "yes" } }, { "uniprot_canonical_ac": "G5E5B4-1", "uniprot_ac": "G5E5B4", "uniprot_id": "G5E5B4_BOVIN", "mass": { "chemical_mass": 46003.0, "monoisotopic_mass": 46003.0 }, "refseq": {}, "gene_names": [], "protein_names": [ { "name": "Ig-like domain-containing protein", "type": "recommended", "evidence": [ { "id": "G5E5B4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G5E5B4/entry#names_and_taxonomy" } ] } ], "function": [], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Bos taurus", "taxid": 9913, "evidence": [ { "database": "UniProtKB", "id": "G5E5B4", "url": "https://www.uniprot.org/uniprotkb/G5E5B4" } ], "common_name": "Bovine", "glygen_name": "Bovine", "reference_species": "Bos taurus [9913]" } ], "gene": [ { "name": "", "url": "https://www.uniprot.org/uniprotkb/G5E5B4", "locus": {} } ], "crossref": [ { "id": "G5E5B4", "url": "https://alphafold.ebi.ac.uk/entry/G5E5B4", "database": "AlphaFoldDB", "categories": [] }, { "id": "ENSBTAG00000049820", "url": "https://bgee.org/?page=gene&gene_id=ENSBTAG00000049820", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "IPR003598", "url": "https://www.ebi.ac.uk/interpro/entry/IPR003598", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR003599", "url": "https://www.ebi.ac.uk/interpro/entry/IPR003599", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR007110", "url": "https://www.ebi.ac.uk/interpro/entry/IPR007110", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR013151", "url": "https://www.ebi.ac.uk/interpro/entry/IPR013151", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR013783", "url": "https://www.ebi.ac.uk/interpro/entry/IPR013783", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR036179", "url": "https://www.ebi.ac.uk/interpro/entry/IPR036179", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR050412", "url": "https://www.ebi.ac.uk/interpro/entry/IPR050412", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "GKTHESW", "url": "https://omabrowser.org/oma/group/GKTHESW/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "PTHR11738", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR11738", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR11738:SF192", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR11738:SF192", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00047", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00047", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF13927", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF13927", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "G5E5B4", "url": "https://www.uniprot.org/uniprotkb/G5E5B4", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "G5E5B4-1", "url": "https://www.uniprot.org/uniprotkb/G5E5B4-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "FLLFSQVVLSLVTCVTVSEYDKPSLSAWPSPMVPLGQTVTLQCHFHSPLKRFRLFKTDGTSLPELHGNHFNTFTLGPVTREHAGSYTCSGFSRSLTVFSRSSDPLQIVVTGVFTKPSISAHPGPLMHVGENVIIRCHSPLLFDKFFLHQENSTGHFQRREEMLTRGHAPADFVIGPMTLASAGTYRCYGSLRRSPYVWSAPSDPVDIVIKGLSKKPSLSAQGGPVVRSGENVTLVCSSKSAFDQFHLLREGDNLGCPLAGGRGPHGVLQAEFPLGPGTPAHSTVYRFYGSFTCSSYSWSDSSDPLFLSVTGSTTSTCPSTMYPHTTEEALLHQEHSSTWYIGLGLVIAFTSTSIILAALVCHWFSTQNNVAVMEGEPNEGQTVNGEDPAAEDVIYAHLNHGTLSERLFTSAPLSPMHPFTEPP", "length": 423, "header": "tr|G5E5B4-1|G5E5B4_BOVIN Isoform 1 of Ig-like domain-containing protein OS=Bos taurus OX=9913 GN= PE=4 SV=3 CANONICAL=G5E5B4-1" }, "isoforms": [ { "isoform_ac": "G5E5B4-1", "url": "https://www.uniprot.org/uniprotkb/G5E5B4/entry", "sequence": { "sequence": "FLLFSQVVLSLVTCVTVSEYDKPSLSAWPSPMVPLGQTVTLQCHFHSPLKRFRLFKTDGTSLPELHGNHFNTFTLGPVTREHAGSYTCSGFSRSLTVFSRSSDPLQIVVTGVFTKPSISAHPGPLMHVGENVIIRCHSPLLFDKFFLHQENSTGHFQRREEMLTRGHAPADFVIGPMTLASAGTYRCYGSLRRSPYVWSAPSDPVDIVIKGLSKKPSLSAQGGPVVRSGENVTLVCSSKSAFDQFHLLREGDNLGCPLAGGRGPHGVLQAEFPLGPGTPAHSTVYRFYGSFTCSSYSWSDSSDPLFLSVTGSTTSTCPSTMYPHTTEEALLHQEHSSTWYIGLGLVIAFTSTSIILAALVCHWFSTQNNVAVMEGEPNEGQTVNGEDPAAEDVIYAHLNHGTLSERLFTSAPLSPMHPFTEPP", "length": 423, "header": "tr|G5E5B4-1|G5E5B4_BOVIN Isoform 1 of Ig-like domain-containing protein OS=Bos taurus OX=9913 GN= PE=4 SV=3 CANONICAL=G5E5B4-1" }, "locus": { "chromosome": "18", "start_pos": 62699762, "end_pos": 62691039, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000011326.7", "url": "https://www.ensembl.org/id/ENSBTAT00000011326.7" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000011326.7", "url": "https://www.ensembl.org/id/ENSBTAP00000011326.7" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [], "orthologs": [], "go_annotation": { "categories": [ { "name": "Biological Process", "total": 1, "go_terms": [ { "name": "immune response-inhibiting cell surface receptor signaling pathway", "id": "GO:0002767", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0002767", "evidence": [ { "database": "UniProtKB", "id": "G5E5B4", "url": "https://www.uniprot.org/uniprotkb/G5E5B4" } ], "pmid": "" } ] }, { "name": "Molecular Function", "total": 2, "go_terms": [ { "name": "transmembrane signaling receptor activity", "id": "GO:0004888", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0004888", "evidence": [ { "database": "UniProtKB", "id": "G5E5B4", "url": "https://www.uniprot.org/uniprotkb/G5E5B4" } ], "pmid": "" }, { "name": "immune receptor activity", "id": "GO:0140375", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0140375", "evidence": [ { "database": "UniProtKB", "id": "G5E5B4", "url": "https://www.uniprot.org/uniprotkb/G5E5B4" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 1, "go_terms": [ { "name": "plasma membrane", "id": "GO:0005886", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005886", "evidence": [ { "database": "UniProtKB", "id": "G5E5B4", "url": "https://www.uniprot.org/uniprotkb/G5E5B4" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 151, "end_pos": 153, "annotation": "n_glycosylation_sequon" }, { "start_pos": 231, "end_pos": 233, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [ { "pdb_id": "AF-G5E5B4-F1", "pdb_chain": "global", "start_pos": 1, "end_pos": 423, "overlap": "1.0", "method": "AlphaFold", "type": "alphafold", "resolution": -1.0, "url": "https://data.glygen.org/ln2downloads/pdb/current/AF-G5E5B4-F1.pdb", "url_external": "https://alphafold.ebi.ac.uk/entry/G5E5B4" } ], "lectin_list": [], 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"database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "Q3ULG3-1", "protein_name": "Steroid receptor-associated and regulated protein", "gene_name": "Srarp", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MAFSKDPRRTSLRDSSVEMSSGTQPSCAPKAMPTAHVTFLIDCATGKQVSLAASTAPPHASRANQGCVAPPMKTFVMFRGKTTMLGTQNISLSRGALDGAKDTLPPYRGLGAPHSLPASLPGPQNDPKAQGSSLKPGATEKHSTREKVKHSLKALTCLCGQVE", "length": 163 }, "evidence": [ { "id": "G5E5E0", "url": "https://omabrowser.org/oma/group/G5E5E0/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q8NEQ6-1", "protein_name": "Steroid receptor-associated and regulated protein", "gene_name": "SRARP", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MAPSEDPRDWRANLKGTIRETGLETSSGGKLAGHQKTVPTAHLTFVIDCTHGKQLSLAATASPPQAPSPNRGLVTPPMKTYIVFCGENWPHLTRVTPMGGGCLAQARATLPLCRGSVASASFPVSPLCPQEVPEAKGKPVKAAPVRSSTWGTVKDSLKALSSCVCGQAD", "length": 169 }, "evidence": [ { "id": "G5E5E0", "url": "https://omabrowser.org/oma/group/G5E5E0/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" } ], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 2, "go_terms": [ { "name": "nucleus", "id": "GO:0005634", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005634", "evidence": [ { "database": "UniProtKB", "id": "G5E5E0", "url": "https://www.uniprot.org/uniprotkb/G5E5E0" } ], "pmid": "" }, { "name": "cytoplasm", "id": "GO:0005737", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005737", "evidence": [ { "database": "UniProtKB", "id": "G5E5E0", "url": "https://www.uniprot.org/uniprotkb/G5E5E0" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 1, "go_terms": [ { "name": "positive regulation of intracellular estrogen receptor signaling pathway", "id": "GO:0033148", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0033148", "evidence": [ { "database": "UniProtKB", "id": "G5E5E0", "url": "https://www.uniprot.org/uniprotkb/G5E5E0" } ], "pmid": "" } ] }, { "name": "Molecular Function", "total": 1, "go_terms": [ { "name": "nuclear estrogen receptor binding", "id": "GO:0030331", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030331", "evidence": [ { "database": "UniProtKB", "id": "G5E5E0", "url": "https://www.uniprot.org/uniprotkb/G5E5E0" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 125, "end_pos": 127, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [ { "pdb_id": "AF-G5E5E0-F1", "pdb_chain": "global", "start_pos": 1, "end_pos": 200, "overlap": "1.0", "method": "AlphaFold", "type": "alphafold", "resolution": -1.0, "url": "https://data.glygen.org/ln2downloads/pdb/current/AF-G5E5E0-F1.pdb", "url_external": "https://alphafold.ebi.ac.uk/entry/G5E5E0" } ], "lectin_list": [], "domain_list": [], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "homologset.oma", "label": "OMA Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 125, "end_pos": 127 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ], "tool_support": { "graph_view": "yes" } }, { "uniprot_canonical_ac": "G5E5F7-1", "uniprot_ac": "G5E5F7", "uniprot_id": "G5E5F7_BOVIN", "mass": { "chemical_mass": 37023.0, "monoisotopic_mass": 37023.0 }, "refseq": { "ac": "XP_059739845", "name": "melanoma-associated antigen B1", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_059739845" }, "gene_names": [ { "name": "MAGEB1", "type": "recommended", "evidence": [ { "id": "G5E5F7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G5E5F7" } ] }, { "name": "MAGEB1", "type": "synonym", "evidence": [ { "id": "XP_059739845", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_059739845" } ] } ], "protein_names": [ { "name": "MAGE domain-containing protein", "type": "recommended", "evidence": [ { "id": "G5E5F7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G5E5F7/entry#names_and_taxonomy" } ] }, { "name": "melanoma-associated antigen B1", "type": "synonym", "evidence": [ { "id": "XP_059739845", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_059739845" } ] } ], "function": [], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Bos taurus", "taxid": 9913, "evidence": [ { "database": "UniProtKB", "id": "G5E5F7", "url": "https://www.uniprot.org/uniprotkb/G5E5F7" } ], "common_name": "Bovine", "glygen_name": "Bovine", "reference_species": "Bos taurus [9913]" } ], "gene": [ { "name": "MAGEB1", "url": "https://www.uniprot.org/uniprotkb/G5E5F7", "locus": {} } ], "crossref": [ { "id": "G5E5F7", "url": "https://alphafold.ebi.ac.uk/entry/G5E5F7", "database": "AlphaFoldDB", "categories": [] }, { "id": "ENSBTAG00000032896", "url": "https://bgee.org/?page=gene&gene_id=ENSBTAG00000032896", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "112445147", "url": "https://www.ncbi.nlm.nih.gov/gene/112445147", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR002190", "url": "https://www.ebi.ac.uk/interpro/entry/IPR002190", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR021072", "url": "https://www.ebi.ac.uk/interpro/entry/IPR021072", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR037445", "url": "https://www.ebi.ac.uk/interpro/entry/IPR037445", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR041898", "url": "https://www.ebi.ac.uk/interpro/entry/IPR041898", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR041899", "url": "https://www.ebi.ac.uk/interpro/entry/IPR041899", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "bta:112445147", "url": "https://www.genome.jp/dbget-bin/www_bget?bta:112445147", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "NGNCARE", "url": "https://omabrowser.org/oma/group/NGNCARE/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "G5E5F7", "url": "https://www.orthodb.org/?gene=G5E5F7", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR11736", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR11736", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR11736:SF155", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR11736:SF155", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF01454", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF01454", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF12440", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF12440", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "XP_059739845", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_059739845", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "G5E5F7", "url": "https://www.uniprot.org/uniprotkb/G5E5F7", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "G5E5F7-1", "url": "https://www.uniprot.org/uniprotkb/G5E5F7-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MPRGQKSKRRAREKRRQARMETKDLGNAQAAATPTPTSGSTPPGSPPAGAGQKPQGAAATSSLVAGASRPRSKARGRRQVKERKNSSQASTSAMIAPLGLLAKKAGMLIHFMLQKFKLKQPIKKIDMLKIVHKAFKAQFPEILKKATDRIELVFGLELKEIKPNGYSYTLVSKERLAKDGVLGSTLEVLKNGLLMPLLGVIFLNGNCASEAEVWDFLNALGIYDGKMHIIFGEPRKFITEELVQEKYLVYRQIPDSDPLSYEFLWGPRAHAETSKMKVLEFVAKINSTVPSAFPFHYEEALREEEERAKAKSASKARGAAKATAHSTVPLSDPSSPQ", "length": 337, "header": "tr|G5E5F7-1|G5E5F7_BOVIN Isoform 1 of MAGE domain-containing protein OS=Bos taurus OX=9913 GN=MAGEB1 PE=4 SV=1 CANONICAL=G5E5F7-1" }, "isoforms": [ { "isoform_ac": "G5E5F7-1", "url": "https://www.uniprot.org/uniprotkb/G5E5F7/entry", "sequence": { "sequence": "MPRGQKSKRRAREKRRQARMETKDLGNAQAAATPTPTSGSTPPGSPPAGAGQKPQGAAATSSLVAGASRPRSKARGRRQVKERKNSSQASTSAMIAPLGLLAKKAGMLIHFMLQKFKLKQPIKKIDMLKIVHKAFKAQFPEILKKATDRIELVFGLELKEIKPNGYSYTLVSKERLAKDGVLGSTLEVLKNGLLMPLLGVIFLNGNCASEAEVWDFLNALGIYDGKMHIIFGEPRKFITEELVQEKYLVYRQIPDSDPLSYEFLWGPRAHAETSKMKVLEFVAKINSTVPSAFPFHYEEALREEEERAKAKSASKARGAAKATAHSTVPLSDPSSPQ", "length": 337, "header": "tr|G5E5F7-1|G5E5F7_BOVIN Isoform 1 of MAGE domain-containing protein OS=Bos taurus OX=9913 GN=MAGEB1 PE=4 SV=1 CANONICAL=G5E5F7-1" }, "locus": { "chromosome": "X", "start_pos": 113343149, "end_pos": 113342139, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000016769.6", "url": "https://www.ensembl.org/id/ENSBTAT00000016769.6" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000016769.5", "url": "https://www.ensembl.org/id/ENSBTAP00000016769.5" } ] } } ], "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "other", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 35, "start_aa": "Thr", "end_pos": 35, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr35", "evidence": [ { "id": "", "database": "GlyGen", "url": "https://data.glygen.org/" } ], "filter_code": "000000000000000010000.00000000001000.0.01000" }, { "glytoucan_ac": "", "type": "O-linked", "subtype": "other", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 37, "start_aa": "Thr", "end_pos": 37, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr37", "evidence": [ { "id": "", "database": "GlyGen", "url": "https://data.glygen.org/" } ], "filter_code": "000000000000000010000.00000000001000.0.01000" } ], "phosphorylation": [], "glycation": [], "keywords": [ "glycoprotein", "glycoprotein_predicted" ], "publication": [], "pathway": [ { "id": "bta:112445147", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?bta:112445147", "resource": "KEGG Pathway" } ], "orthologs": [ { "uniprot_canonical_ac": "A2A9R3-1", "protein_name": "Melanoma-associated antigen B4", "gene_name": "Mageb4", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MPRGQKSKARAREKRRLVQDEAQELQDAQAKAGEKGKSPSCSNQDSGDAVASTSTAGFPQKSKSQGEAPTTTARKGGACRRSRKSTRGPREESTSCTRVPRFSENPQNDLLTRKTGMLMQYLLCKYKMKQPASKGEMLKVINRRFKEQLPEILKKASERIQLVFGLEVKEIKPNGGYYTLVSKLDPSVGNALTTSLPFPQNGLLMPLLGVIFLNGNRASEAEIWEFLNVLGIYDGKVHIIFGEPRKLITRDLVKEKYLVYQKEANSDPPSFEFLWGPRAYAETTKMKILEFLAEVNETVPQAFPTHYEEALRDQEERAQAEAVGSPGTSAKDKAEAKVTLVDSSCKYQAESKVTLVDSSCKDQAESKVTLVDPSCKDNAKSKVTLGSSRKYKAKSKVPLVDSSCKDQAESKVTLVDSCKDQAESKVTLVDSSCKDQAESKVTLVDSSCKDQAESKVTLVDPSCKDKAKSKVTLGSSHKYKAKSKVTLVDSSCKDQAESKVTLVDSSCKDQAESKVTLVDPSCKDNAKSKVTLGSSRKYKAKSKVPLVDSSGKDKAV", "length": 556 }, "evidence": [ { "id": "G5E5F7", "url": "https://omabrowser.org/oma/group/G5E5F7/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "O15481-1", "protein_name": "Melanoma-associated antigen B4", "gene_name": "MAGEB4", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MPRGQKSKLRAREKRQRTRGQTQDLKVGQPTAAEKEESPSSSSSVLRDTASSSLAFGIPQEPQREPPTTSAAAAMSCTGSDKGDESQDEENASSSQASTSTERSLKDSLTRKTKMLVQFLLYKYKMKEPTTKAEMLKIISKKYKEHFPEIFRKVSQRTELVFGLALKEVNPTTHSYILVSMLGPNDGNQSSAWTLPRNGLLMPLLSVIFLNGNCAREEEIWEFLNMLGIYDGKRHLIFGEPRKLITQDLVQEKYLEYQQVPNSDPPRYQFLWGPRAHAETSKMKVLEFLAKVNDTTPNNFPLLYEEALRDEEERAGARPRVAARRGTTAMTSAYSRATSSSSSQPM", "length": 346 }, "evidence": [ { "id": "G5E5F7", "url": "https://omabrowser.org/oma/group/G5E5F7/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" } ], "go_annotation": { "categories": [ { "name": "Biological Process", "total": 1, "go_terms": [ { "name": "negative regulation of transcription by RNA polymerase II", "id": "GO:0000122", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000122", "evidence": [ { "database": "UniProtKB", "id": "G5E5F7", "url": "https://www.uniprot.org/uniprotkb/G5E5F7" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 1, "go_terms": [ { 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"interactions": [], "reactions": [ { "id": "32823", "name": "", "equation": "phosphate(in) = phosphate(out)", "summary": "", "cellular_location": "", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [], "evidence": [ { "id": "32823", "database": "Rhea", "url": "https://www.rhea-db.org/rhea/32823" } ] }, { "id": "34983", "name": "", "equation": "sulfate(in) = sulfate(out)", "summary": "", "cellular_location": "", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [], "evidence": [ { "id": "34983", "database": "Rhea", "url": "https://www.rhea-db.org/rhea/34983" } ] }, { "id": "71615", "name": "", "equation": "(S)-malate(in) + sulfate(out) = (S)-malate(out) + sulfate(in)", "summary": "", "cellular_location": "", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [], "evidence": [ { "id": "71615", "database": "Rhea", "url": "https://www.rhea-db.org/rhea/71615" } ] }, { "id": "71631", "name": "", "equation": "sulfate(out) + phosphate(in) = sulfate(in) + phosphate(out)", "summary": "", "cellular_location": "", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [], "evidence": [ { "id": "71631", "database": "Rhea", "url": "https://www.rhea-db.org/rhea/71631" } ] }, { "id": "72275", "name": "", "equation": "oxalate(in) + sulfate(out) = oxalate(out) + sulfate(in)", "summary": "", "cellular_location": "", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [], "evidence": [ { "id": "72275", "database": "Rhea", "url": "https://www.rhea-db.org/rhea/72275" } ] }, { "id": "73195", "name": "", "equation": "malonate(in) + sulfate(out) = malonate(out) + sulfate(in)", "summary": "", "cellular_location": "", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [], "evidence": [ { "id": "73195", "database": "Rhea", "url": "https://www.rhea-db.org/rhea/73195" } ] }, { "id": "73199", "name": "", "equation": "maleate(in) + sulfate(out) = maleate(out) + sulfate(in)", "summary": "", "cellular_location": "", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [], "evidence": [ { "id": "73199", "database": "Rhea", "url": "https://www.rhea-db.org/rhea/73199" } ] }, { "id": "73207", "name": "", "equation": "sulfite(in) + sulfate(out) = sulfite(out) + sulfate(in)", "summary": "", "cellular_location": "", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [], "evidence": [ { "id": "73207", "database": "Rhea", "url": "https://www.rhea-db.org/rhea/73207" } ] }, { "id": "73215", "name": "", "equation": "thiosulfate(in) + sulfate(out) = thiosulfate(out) + sulfate(in)", "summary": "", "cellular_location": "", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [], "evidence": [ { "id": "73215", "database": "Rhea", "url": "https://www.rhea-db.org/rhea/73215" } ] }, { "id": "73223", "name": "", "equation": "(3S)-citramalate(in) + sulfate(out) = 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"crossref": [ { "id": "G5E5N2", "url": "https://alphafold.ebi.ac.uk/entry/G5E5N2", "database": "AlphaFoldDB", "categories": [] }, { "id": "ENSBTAG00000019814", "url": "https://bgee.org/?page=gene&gene_id=ENSBTAG00000019814", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "101907155", "url": "https://www.ncbi.nlm.nih.gov/gene/101907155", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR029526", "url": "https://www.ebi.ac.uk/interpro/entry/IPR029526", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR052638", "url": "https://www.ebi.ac.uk/interpro/entry/IPR052638", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "bta:101907155", "url": "https://www.genome.jp/dbget-bin/www_bget?bta:101907155", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "CCHDAQV", "url": "https://omabrowser.org/oma/group/CCHDAQV/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "G5E5N2", "url": "https://www.orthodb.org/?gene=G5E5N2", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR47055", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR47055", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR47055:SF2", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR47055:SF2", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF13843", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF13843", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "XP_005209310", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_005209310", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "G5E5N2", "url": "https://www.uniprot.org/uniprotkb/G5E5N2", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "G5E5N2-1", "url": "https://www.uniprot.org/uniprotkb/G5E5N2-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MASSSSGLFTGKSTSSKLKSVKLLEVLNALEEEESGHSREEIFIAPPKNAAGDFTDEDSGDEDGQRGTHVPGNVLHAFVVPEDSGTGEEEEEDLQLQPAMKKQKAVVEPQRVWTKRDIRPDFSSWTATDPHMEDLKSQELSPVGLFELFFDEGTINFIVNETNRYARQKNVNLGLTAQELKCVLGILILSGYISYPRRRMFWETSPDSHHHLVADAIRRDRFELIFSYLHFADNNELDESDRFAKVRPLIVRMNYNFQKHAPLEEFYSFGESMCEYFGYRGSKQLPAGKPVRLGYKIWCGTTSRGYLVWFEPSQGTLFTKPDRGLDLGGSMVVKFVDALQTRGCLPYHIFFDKVFTSVKLMSILRKKGVKATGTVREYRTERCPLKDPKELKKMKRGSFDYKVDESEEIIVCRWHDSSVVNICSNAVGIEPVGLTSHHSGANKMQTQVHQPSLLRLYQEKVGGVGRMDQNIAKYKVKIRGMKWYSSFIGYVIDAALNNAWQLHRICCHDAQVDLLAFRRYVACVYLESNADTSSQGRRSRRLETESRFDMIGHWIIHQDKRTRCALCHSQTNTRCEKCQKGVHAKCFRAYHIR", "length": 593, "header": "tr|G5E5N2-1|G5E5N2_BOVIN Isoform 1 of PiggyBac transposable element derived 2 OS=Bos taurus OX=9913 GN=PGBD2 PE=4 SV=2 CANONICAL=G5E5N2-1" }, "isoforms": [ { "isoform_ac": "G5E5N2-1", "url": "https://www.uniprot.org/uniprotkb/G5E5N2/entry", "sequence": { "sequence": "MASSSSGLFTGKSTSSKLKSVKLLEVLNALEEEESGHSREEIFIAPPKNAAGDFTDEDSGDEDGQRGTHVPGNVLHAFVVPEDSGTGEEEEEDLQLQPAMKKQKAVVEPQRVWTKRDIRPDFSSWTATDPHMEDLKSQELSPVGLFELFFDEGTINFIVNETNRYARQKNVNLGLTAQELKCVLGILILSGYISYPRRRMFWETSPDSHHHLVADAIRRDRFELIFSYLHFADNNELDESDRFAKVRPLIVRMNYNFQKHAPLEEFYSFGESMCEYFGYRGSKQLPAGKPVRLGYKIWCGTTSRGYLVWFEPSQGTLFTKPDRGLDLGGSMVVKFVDALQTRGCLPYHIFFDKVFTSVKLMSILRKKGVKATGTVREYRTERCPLKDPKELKKMKRGSFDYKVDESEEIIVCRWHDSSVVNICSNAVGIEPVGLTSHHSGANKMQTQVHQPSLLRLYQEKVGGVGRMDQNIAKYKVKIRGMKWYSSFIGYVIDAALNNAWQLHRICCHDAQVDLLAFRRYVACVYLESNADTSSQGRRSRRLETESRFDMIGHWIIHQDKRTRCALCHSQTNTRCEKCQKGVHAKCFRAYHIR", "length": 593, "header": "tr|G5E5N2-1|G5E5N2_BOVIN Isoform 1 of PiggyBac transposable element derived 2 OS=Bos taurus OX=9913 GN=PGBD2 PE=4 SV=2 CANONICAL=G5E5N2-1" }, "locus": { "chromosome": "7", "start_pos": 42735804, "end_pos": 42731200, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000026396.8", "url": "https://www.ensembl.org/id/ENSBTAT00000026396.8" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000026396.6", "url": "https://www.ensembl.org/id/ENSBTAP00000026396.6" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [ { "id": "bta:101907155", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?bta:101907155", "resource": "KEGG Pathway" } ], "orthologs": [ { "uniprot_canonical_ac": "Q6P3X8-1", "protein_name": "PiggyBac transposable element-derived protein 2", "gene_name": "PGBD2", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MASTSRDVIAGRGIHSKVKSAKLLEVLNAMEEEESNNNREEIFIAPPDNAAGEFTDEDSGDEDSQRGAHLPGSVLHASVLCEDSGTGEDNDDLELQPAKKRQKAVVKPQRIWTKRDIRPDFGSWTASDPHIEDLKSQELSPVGLFELFFDEGTINFIVNETNRYAWQKNVNLSLTAQELKCVLGILILSGYISYPRRRMFWETSPDSHHHLVADAIRRDRFELIFSYLHFADNNELDASDRFAKVRPLIIRMNCNFQKHAPLEEFYSFGESMCEYFGHRGSKQLHRGKPVRLGYKIWCGTTSRGYLVWFEPSQGTLFTKPDRSLDLGGSMVIKFVDALQERGFLPYHIFFDKVFTSVKLMSILRKKGVKATGTVREYRTERCPLKDPKELKKMKRGSFDYKVDESEEIIVCRWHDSSVVNICSNAVGIEPVRLTSRHSGAAKTRTQVHQPSLVKLYQEKVGGVGRMDQNIAKYKVKIRGMKWYSSFIGYVIDAALNNAWQLHRICCQDAQVDLLAFRRYIACVYLESNADTTSQGRRSRRLETESRFDMIGHWIIHQDKRTRCALCHSQTNTRCEKCQKGVHAKCFREYHIR", "length": 592 }, "evidence": [ { "id": "G5E5N2", "url": "https://omabrowser.org/oma/group/G5E5N2/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" } ], "go_annotation": { "categories": [ { "name": "Molecular Function", "total": 1, "go_terms": [ { "name": "sequence-specific DNA binding", "id": "GO:0043565", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0043565", "evidence": [ { "database": "UniProtKB", "id": "G5E5N2", "url": "https://www.uniprot.org/uniprotkb/G5E5N2" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 160, "end_pos": 162, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [ { "pdb_id": "AF-G5E5N2-F1", "pdb_chain": "global", "start_pos": 1, "end_pos": 593, "overlap": "1.0", "method": "AlphaFold", "type": "alphafold", "resolution": -1.0, "url": "https://data.glygen.org/ln2downloads/pdb/current/AF-G5E5N2-F1.pdb", "url_external": "https://alphafold.ebi.ac.uk/entry/G5E5N2" } ], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "G5E5N2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G5E5N2" }, { "id": "PF13843", "database": "Pfam", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF13843" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "PiggyBac transposable element-derived protein", "eco_id": "ECO_0000259", "start_pos": 141, "end_pos": 500, "start_aa": "Ser", "end_aa": "Trp", "glycosite_overlap": [] } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "homologset.oma", "label": "OMA Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 160, "end_pos": 162 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ], "tool_support": { "graph_view": "yes" } }, { "uniprot_canonical_ac": "G5E5N7-1", "uniprot_ac": "G5E5N7", "uniprot_id": "G5E5N7_BOVIN", "mass": { "chemical_mass": 46735.0, "monoisotopic_mass": 46735.0 }, "refseq": {}, "gene_names": [ { "name": "IL13RA2", "type": "recommended", "evidence": [ { "id": "G5E5N7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G5E5N7" } ] } ], "protein_names": [ { "name": "Interleukin-13 receptor subunit alpha-2", "type": "recommended", "evidence": [ { "id": "G5E5N7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G5E5N7/entry#names_and_taxonomy" } ] } ], "function": [ { "annotation": "Cell surface receptor that plays a role in the regulation of IL-13-mediated responses. Functions as a decoy receptor that inhibits IL-13- and IL-4-mediated signal transduction via the JAK-STAT pathway and thereby modulates immune responses and inflammation. Serves as a functional signaling receptor for IL-13 in an alternative pathway involving AP-1 ultimately leading to the production of TGFB1.", "evidence": [ { "database": "UniProtKB", "id": "G5E5N7", "url": "https://www.uniprot.org/uniprotkb/G5E5N7#function" }, { "database": "UniProtKB", "id": "ARBA00055505", "url": "https://www.uniprot.org/uniprotkb/ARBA00055505#function" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Bos taurus", "taxid": 9913, "evidence": [ { "database": "UniProtKB", "id": "G5E5N7", "url": "https://www.uniprot.org/uniprotkb/G5E5N7" } ], "common_name": "Bovine", "glygen_name": "Bovine", "reference_species": "Bos taurus [9913]" } ], "gene": [ { "name": "IL13RA2", "url": "https://www.uniprot.org/uniprotkb/G5E5N7", "locus": { "chromosome": "X", "start_pos": 63531315, "end_pos": 63552085, "strand": "+", "evidence": [ { "database": "Ensembl Gene", "id": "ENSBTAG00000020022", "url": "https://www.ensembl.org/id/ENSBTAG00000020022" } ] } } ], "crossref": [ { "id": "G5E5N7", "url": "https://alphafold.ebi.ac.uk/entry/G5E5N7", "database": "AlphaFoldDB", "categories": [] }, { "id": "ENSBTAG00000020022", "url": "https://bgee.org/?page=gene&gene_id=ENSBTAG00000020022", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "cd00063", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd00063", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "IPR003532", "url": "https://www.ebi.ac.uk/interpro/entry/IPR003532", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR003961", "url": "https://www.ebi.ac.uk/interpro/entry/IPR003961", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR013783", "url": "https://www.ebi.ac.uk/interpro/entry/IPR013783", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR015321", "url": "https://www.ebi.ac.uk/interpro/entry/IPR015321", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR036116", "url": "https://www.ebi.ac.uk/interpro/entry/IPR036116", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "GPIPSQC", "url": "https://omabrowser.org/oma/group/GPIPSQC/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "G5E5N7", "url": "https://www.orthodb.org/?gene=G5E5N7", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR23037", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR23037", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR23037:SF45", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR23037:SF45", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF09240", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF09240", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "R-BTA-6785807", "url": "https://www.reactome.org/PathwayBrowser/#R-BTA-6785807", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "G5E5N7", "url": "https://www.uniprot.org/uniprotkb/G5E5N7", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "G5E5N7-1", "url": "https://www.uniprot.org/uniprotkb/G5E5N7-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MRTLQLEQSGNFKVLNLREMAFIHLDIRCLYTLLICTAFGSTLSSNAEIKVNPPQDFQIVDPGYLGYLYLQWQPPVSLDNFNKCTVEYELKYRNVDSESWRTIITKNLLYKDGFDLNKGVEAKIHTLLPRQCTNGSEVQSSWSEATYWISSQGNLDTKIQDMDCVYYNWQYLLCSWKPGMGAHLDSNYRLYYWYEGLDHVLECIDYIQAKGKNIGCRFPYLESSDYKDFYICVNGSSESQLIRPSYFIFQLQNIVKPLPPDYLSLTMKNSEVNLKWSIPRGPIPAKCLIYEIEFTEDDTAWVTTTIENEIYITRTSNESLQLCFLVRSKMNIYCADDGIWSEWSDEQCWKGDIWKEILLFFLVPFVLVSLFVLIVTCTLLYKQRNLLKMVFHTEKRSPF", "length": 399, "header": "tr|G5E5N7-1|G5E5N7_BOVIN Isoform 1 of Interleukin-13 receptor subunit alpha-2 OS=Bos taurus OX=9913 GN=IL13RA2 PE=3 SV=1 CANONICAL=G5E5N7-1" }, "isoforms": [ { "isoform_ac": "G5E5N7-1", "url": "https://www.uniprot.org/uniprotkb/G5E5N7/entry", "sequence": { "sequence": "MRTLQLEQSGNFKVLNLREMAFIHLDIRCLYTLLICTAFGSTLSSNAEIKVNPPQDFQIVDPGYLGYLYLQWQPPVSLDNFNKCTVEYELKYRNVDSESWRTIITKNLLYKDGFDLNKGVEAKIHTLLPRQCTNGSEVQSSWSEATYWISSQGNLDTKIQDMDCVYYNWQYLLCSWKPGMGAHLDSNYRLYYWYEGLDHVLECIDYIQAKGKNIGCRFPYLESSDYKDFYICVNGSSESQLIRPSYFIFQLQNIVKPLPPDYLSLTMKNSEVNLKWSIPRGPIPAKCLIYEIEFTEDDTAWVTTTIENEIYITRTSNESLQLCFLVRSKMNIYCADDGIWSEWSDEQCWKGDIWKEILLFFLVPFVLVSLFVLIVTCTLLYKQRNLLKMVFHTEKRSPF", "length": 399, "header": "tr|G5E5N7-1|G5E5N7_BOVIN Isoform 1 of Interleukin-13 receptor subunit alpha-2 OS=Bos taurus OX=9913 GN=IL13RA2 PE=3 SV=1 CANONICAL=G5E5N7-1" }, "locus": { "chromosome": "X", "start_pos": 63551883, "end_pos": 63531426, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000026668.7", "url": "https://www.ensembl.org/id/ENSBTAT00000026668.7" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000026668.6", "url": "https://www.ensembl.org/id/ENSBTAP00000026668.6" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [ { "id": "R-BTA-6785807", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-BTA-6785807", "resource": "Reactome", "description": "Interleukin-4 and Interleukin-13 signaling" } ], "orthologs": [ { "uniprot_canonical_ac": "A0A8V0Z8N4-1", "protein_name": "Interleukin 13 receptor subunit alpha 2", "gene_name": "IL13RA2", "tax_id": 9031, "organism": "Gallus gallus", "sequence": { "sequence": "MSSQISAGGSEQAVFFPFLFLHAHPIHRTLPGRLLGCNCLKLSRTRNRCEAFPFISLLHFAFFFFLQLVDTFSLHVTWSRGKPGAAAREFHGPTAVIEAFHHHTAPAMLCRRAPPAPAMALQPISLLSLVLAWGCVASSSLWHTAVAPPQDLQITDPGLLGSLDIEWKPPPNIQTSNGCTVKYKCEYRNAGDREWKVIFTRKLKLRVGFDLSRTAEVKVQTLLKGWCTNDVEVQSEWLYATFRVPLQGKLESEVQNFHCIYHDWEYLKCTWQPGLLAPRGVNYGLYYWYEGLEHTVQCDHYIQDHGVNMGCMLQNLSQAEYKDLSICVNGSVAATLLRPLYATLRLHNLAKPSPPQQLVVSMSAAEELRVVWSPPGGQTPPQCLEYEVQLAEEQGEAKAAWASVSTQVETAFTISRANRSRVSCVRVRGRTNNFCADEGFWSEWTQECFSVSRKEVKQLFILIPVILGLSSSLLIFTLIGQCKKKSPAGKPSHTLVGC", "length": 498 }, "evidence": [ { "id": "G5E5N7", "url": "https://omabrowser.org/oma/group/G5E5N7/", "database": "OMA" } ], "glygen_name": "Chicken", "common_name": "Chicken" }, { "uniprot_canonical_ac": "F1RWT5-1", "protein_name": "Interleukin-13 receptor subunit alpha-2", "gene_name": "IL13RA2", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MAFIHVNIRCLYTLLICTAFGSTLSSNAEIKVNPPQDFEIVDPGYLGYLYLQWQPPLSLDNFKECTVEYELKYRNIDSESWKTIITKNLHYKDGFDLNKGVEAKIHTLLPGQCTNGSEVQSSWSETTYWTLPQGNLETKIQDMDCVYYNWQYLLCSWKPGMGVHFDTNYNLFYWYEGLDHALQCADYIKTNGKNTGCRFPYLESSDYKDFYICVNGSSESQSIRPSYFIFQLQNIVKPLPPDYLSLTVKNSEEVNLKWSIPRGPIPSQCFIYEIEFTEDDTTWVTTTDENEIYITRTSNESHRLCFSVRSKMNIYCSDDGIWSEWSDEQCWKGDIWKETLVFFLIPFAFVSLLVLLITCLLLYKQKNLLKMIFHTKKEAFSHQDTLC", "length": 387 }, "evidence": [ { "id": "G5E5N7", "url": "https://omabrowser.org/oma/group/G5E5N7/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "O88786-1", "protein_name": "Interleukin-13 receptor subunit alpha-2", "gene_name": "Il13ra2", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MAFVHIRCLCFILLCTITGYSLEIKVNPPQDFEILDPGLLGYLYLQWKPPVVIEKFKGCTLEYELKYRNVDSDSWKTIITRNLIYKDGFDLNKGIEGKIRTHLSEHCTNGSEVQSPWIEASYGISDEGSLETKIQDMKCIYYNWQYLVCSWKPGKTVYSDTNYTMFFWYEGLDHALQCADYLQHDEKNVGCKLSNLDSSDYKDFFICVNGSSKLEPIRSSYTVFQLQNIVKPLPPEFLHISVENSIDIRMKWSTPGGPIPPRCYTYEIVIREDDISWESATDKNDMKLKRRANESEDLCFFVRCKVNIYCADDGIWSEWSEEECWEGYTGPDSKIIFIVPVCLFFIFLLLLLCLIVEKEEPEPTLSLHVDLNKEVCAYEDTLC", "length": 383 }, "evidence": [ { "id": "G5E5N7", "url": "https://omabrowser.org/oma/group/G5E5N7/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q14627-1", "protein_name": "Interleukin-13 receptor subunit alpha-2", "gene_name": "IL13RA2", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MAFVCLAIGCLYTFLISTTFGCTSSSDTEIKVNPPQDFEIVDPGYLGYLYLQWQPPLSLDHFKECTVEYELKYRNIGSETWKTIITKNLHYKDGFDLNKGIEAKIHTLLPWQCTNGSEVQSSWAETTYWISPQGIPETKVQDMDCVYYNWQYLLCSWKPGIGVLLDTNYNLFYWYEGLDHALQCVDYIKADGQNIGCRFPYLEASDYKDFYICVNGSSENKPIRSSYFTFQLQNIVKPLPPVYLTFTRESSCEIKLKWSIPLGPIPARCFDYEIEIREDDTTLVTATVENETYTLKTTNETRQLCFVVRSKVNIYCSDDGIWSEWSDKQCWEGEDLSKKTLLRFWLPFGFILILVIFVTGLLLRKPNTYPKMIPEFFCDT", "length": 380 }, "evidence": [ { "id": "G5E5N7", "url": "https://omabrowser.org/oma/group/G5E5N7/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "Q8VHK6-1", "protein_name": "Interleukin-13 receptor subunit alpha-2", "gene_name": "Il13ra2", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MALMAVNTRCLCLFLLCTITGHSLEIKVNPPQDFEILDPGLLGYLYLQWKPPVVMDNFKECKLEYELKYRNVDSDSWKTIITRNLIYKDGFDLNKGIEGKIRTHLSEHCTNGSEVQSPWTEASYGIADEGSLGTKIQDMKCIYYNWQYLVCSWKPGKTVHSDTNYTMFFWYEGLDHALQCADYLQDNEKNVGCKLSNLDSSDYKDFFIRVNGSSKLEPIRSSYMVFQLQNIVKPLPPEFLHISVENSIDIRMKWSTPGGPIPPSCYTYEIVVREDDISWESATDKNDMKLKRRANESEDLCFFVRCKINIYCADDGIWSEWSEEECWEGYTGPDSKIVFIVPVCLFFIFLLLLLCLIVEKEDPEPTLSLHVDLNKEMYAYEETLC", "length": 385 }, "evidence": [ { "id": "G5E5N7", "url": "https://omabrowser.org/oma/group/G5E5N7/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" } ], "go_annotation": { "categories": [ { "name": "Biological Process", "total": 2, "go_terms": [ { "name": "positive regulation of cell population proliferation", "id": "GO:0008284", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008284", "evidence": [ { "database": "UniProtKB", "id": "G5E5N7", "url": "https://www.uniprot.org/uniprotkb/G5E5N7" } ], "pmid": "" }, { "name": "cytokine-mediated signaling pathway", "id": "GO:0019221", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0019221", "evidence": [ { "database": "UniProtKB", "id": "G5E5N7", "url": "https://www.uniprot.org/uniprotkb/G5E5N7" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 2, "go_terms": [ { "name": "receptor complex", "id": "GO:0043235", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0043235", "evidence": [ { "database": "UniProtKB", "id": "G5E5N7", "url": "https://www.uniprot.org/uniprotkb/G5E5N7" } ], "pmid": "" }, { "name": "external side of plasma membrane", "id": "GO:0009897", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0009897", "evidence": [ { "database": "UniProtKB", "id": "G5E5N7", "url": "https://www.uniprot.org/uniprotkb/G5E5N7" } ], "pmid": "" } ] }, { "name": "Molecular Function", "total": 2, "go_terms": [ { "name": "cytokine binding", "id": "GO:0019955", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0019955", "evidence": [ { "database": "UniProtKB", "id": "G5E5N7", "url": "https://www.uniprot.org/uniprotkb/G5E5N7" } ], "pmid": "" }, { "name": "cytokine receptor activity", "id": "GO:0004896", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0004896", "evidence": [ { "database": "UniProtKB", "id": "G5E5N7", "url": "https://www.uniprot.org/uniprotkb/G5E5N7" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 134, "end_pos": 136, "annotation": "n_glycosylation_sequon" }, { "start_pos": 234, "end_pos": 236, "annotation": "n_glycosylation_sequon" }, { "start_pos": 317, "end_pos": 319, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [ { "pdb_id": "AF-G5E5N7-F1", "pdb_chain": "global", "start_pos": 1, "end_pos": 399, "overlap": "1.0", "method": "AlphaFold", "type": "alphafold", "resolution": -1.0, "url": "https://data.glygen.org/ln2downloads/pdb/current/AF-G5E5N7-F1.pdb", "url_external": "https://alphafold.ebi.ac.uk/entry/G5E5N7" } ], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "G5E5N7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G5E5N7" }, { "id": "PS50853", "database": "PROSITE", "url": "https://prosite.expasy.org/PS50853" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "Fibronectin type-III", "eco_id": "ECO_0000259", "start_pos": 53, "end_pos": 154, "start_aa": "Pro", "end_aa": "Asn", "glycosite_overlap": [] } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "homologset.oma", "label": "OMA Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 134, "end_pos": 136 }, { "start_pos": 234, "end_pos": 236 }, { "start_pos": 317, "end_pos": 319 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, 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Classification" ] }, { "id": "RMVMIAN", "url": "https://omabrowser.org/oma/group/RMVMIAN/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "G5E5P6", "url": "https://www.orthodb.org/?gene=G5E5P6", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR10983", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR10983", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR10983:SF9", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR10983:SF9", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF01553", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF01553", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF16076", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF16076", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "R-BTA-1483166", "url": "https://www.reactome.org/PathwayBrowser/#R-BTA-1483166", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "R-BTA-6811436", "url": "https://www.reactome.org/PathwayBrowser/#R-BTA-6811436", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "G5E5P6", "url": "https://www.uniprot.org/uniprotkb/G5E5P6", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "G5E5P6-1", "url": "https://www.uniprot.org/uniprotkb/G5E5P6-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MGLLAFLKTQFVVHLLIGFVFVVSGLVINSIQLCTLVLWPVNKQLYRRLNCRLAYSLWSQLVMLLEWWSCTECTLFTDQATVDTFGKEHAVIILNHNFEIDFLCGWTMCERFGVLGSSKVLAKRELLYVPLIGWTWYFLEIVFCKRKWEEDRDTVIKGLKSLANYPEYMWFLLYCEGTRFTEKKHRVSMEVAASKGLPVLKYHLLPRTKGFTTAVQCLRGTVTAVYDVTLNFRGNKNPSLLGILYGKKYEADMCVRRFPLEEIPLDEKEAAQWLHKLYQEKDALQEIYNQKGVFPGQQFKPTRRPWTLLNFLFWATLLLSPLFSFVLGVFASGSPLLILTFLGFVGAASFGVRRLIGVTEIEKGSSYGNQEFKKKE", "length": 376, "header": "tr|G5E5P6-1|G5E5P6_BOVIN Isoform 1 of 1-acylglycerol-3-phosphate O-acyltransferase 3 OS=Bos taurus OX=9913 GN=AGPAT3 PE=3 SV=1 CANONICAL=G5E5P6-1" }, "isoforms": [ { "isoform_ac": "G5E5P6-1", "url": "https://www.uniprot.org/uniprotkb/G5E5P6/entry", "sequence": { "sequence": "MGLLAFLKTQFVVHLLIGFVFVVSGLVINSIQLCTLVLWPVNKQLYRRLNCRLAYSLWSQLVMLLEWWSCTECTLFTDQATVDTFGKEHAVIILNHNFEIDFLCGWTMCERFGVLGSSKVLAKRELLYVPLIGWTWYFLEIVFCKRKWEEDRDTVIKGLKSLANYPEYMWFLLYCEGTRFTEKKHRVSMEVAASKGLPVLKYHLLPRTKGFTTAVQCLRGTVTAVYDVTLNFRGNKNPSLLGILYGKKYEADMCVRRFPLEEIPLDEKEAAQWLHKLYQEKDALQEIYNQKGVFPGQQFKPTRRPWTLLNFLFWATLLLSPLFSFVLGVFASGSPLLILTFLGFVGAASFGVRRLIGVTEIEKGSSYGNQEFKKKE", "length": 376, "header": "tr|G5E5P6-1|G5E5P6_BOVIN Isoform 1 of 1-acylglycerol-3-phosphate O-acyltransferase 3 OS=Bos taurus OX=9913 GN=AGPAT3 PE=3 SV=1 CANONICAL=G5E5P6-1" }, "locus": { "chromosome": "1", "start_pos": 144025620, "end_pos": 144009058, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000027260.8", "url": "https://www.ensembl.org/id/ENSBTAT00000027260.8" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000027260.5", "url": "https://www.ensembl.org/id/ENSBTAP00000027260.5" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [ { "id": "R-BTA-1483166", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-BTA-1483166", "resource": "Reactome", "description": "Synthesis of PA" }, { "id": "R-BTA-6811436", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-BTA-6811436", "resource": "Reactome", "description": "COPI-independent Golgi-to-ER retrograde traffic" } ], "orthologs": [ { "uniprot_canonical_ac": "A0A1D5PUB7-1", "protein_name": "1-acylglycerol-3-phosphate O-acyltransferase 3", "gene_name": "AGPAT3", "tax_id": 9031, "organism": "Gallus gallus", "sequence": { "sequence": "MGFIAFLKTQFIVHLLIGFVFVVSGLIINFIQLCTLVLWPINKQFYRRVNCRLAYSLWSQLVMLLEWWSGTECTLFSDEATVNTFGKEHVIIILNHNFEIDFLCGWTMTERFGVLGSSKVLAKKELLYVPLIGWTWYFLEIVFCKRKWEEDRDTVIEGLKRLADYPEYMWFLLYCEGTRFTETKHRISMEVAESKGLPKLKYHLLPRTKGFTTAVQCLRGTVSAVYDVTLNFRGNKNPSLLGILYGKKYEADMCVRRFPLEDIPQDEKEAANWLHKLYQEKDALQEMYNQEGTFPGQQFKPPRRPWTLVNFLFWATVLLSPLFTFGFGVFASGSPLLILAFLGFVGAASFGVRRLIGVTEIEKGSSYGNQEFKKKE", "length": 376 }, "evidence": [ { "id": "G5E5P6", "url": "https://omabrowser.org/oma/group/G5E5P6/", "database": "OMA" } ], "glygen_name": "Chicken", "common_name": "Chicken" }, { "uniprot_canonical_ac": "G3V648-1", "protein_name": "1-acylglycerol-3-phosphate O-acyltransferase 3", "gene_name": "Agpat3", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MGLLAYLKTQFVVHLLIGFVFVVSGLIINFTQLCTLALWPISKNLYRRINCRLAYSLWSQLVMLLEWWSCTECTLFTDQATVNHFGKEHVVVILNHNFEIDFLCGWTMCERFGVLGSSKVLAKRELLYVPLIGWTWYFLEIVFCKRKWEEDRDTVIEGLRRLANYPEYMWFLLYCEGTRFTETKHRVSMEVAASKGLPPLKYHLLPRTKGFTTAVQCLRGTVAAIYDVTLNFRGNKNPSLLGILYGKKYEADMCVRRFPLEDIPADETGAAQWLHKLYQEKDALQEMYKQSGVFPGEQIKPARRPWTLLNFLCWATFLLSPLFSFVLGVFASGSPLLILTFLGFVGAASFGVRRLIGVTEIEKGSSYGNQELKKKE", "length": 376 }, "evidence": [ { "id": "G5E5P6", "url": "https://omabrowser.org/oma/group/G5E5P6/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "Q9D517-1", "protein_name": "1-acyl-sn-glycerol-3-phosphate acyltransferase gamma", "gene_name": "Agpat3", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MGLLAYLKTQFVVHLLIGFVFVVSGLIINFTQLCTLALWPISKHLYRRINCRLAYSLWSQLVMLLEWWSCTECTLFTDQATVDHFGKEHVVVILNHNFEIDFLCGWTMCERFGVLGSSKVLAKRELLCVPLIGWTWYFLEIVFCKRKWEEDRDTVIEGLRRLADYPEYMWFLLYCEGTRFTETKHRISMEVAASKGLPPLKYHLLPRTKGFTTAVQCLRGTVAAIYDVTLNFRGNKNPSLLGILYGKKYEADMCVRRFPLEDIPADETSAAQWLHKLYQEKDALQEMYKQKGVFPGEQFKPARRPWTLLNFLCWATILLSPLFSFVLGVFASGSPLLILTFLGFVGAASFGVRRLIGVTEIEKGSSYGNQELKKKE", "length": 376 }, "evidence": [ { "id": "G5E5P6", "url": "https://omabrowser.org/oma/group/G5E5P6/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q9NRZ7-1", "protein_name": "1-acyl-sn-glycerol-3-phosphate acyltransferase gamma", "gene_name": "AGPAT3", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MGLLAFLKTQFVLHLLVGFVFVVSGLVINFVQLCTLALWPVSKQLYRRLNCRLAYSLWSQLVMLLEWWSCTECTLFTDQATVERFGKEHAVIILNHNFEIDFLCGWTMCERFGVLGSSKVLAKKELLYVPLIGWTWYFLEIVFCKRKWEEDRDTVVEGLRRLSDYPEYMWFLLYCEGTRFTETKHRVSMEVAAAKGLPVLKYHLLPRTKGFTTAVKCLRGTVAAVYDVTLNFRGNKNPSLLGILYGKKYEADMCVRRFPLEDIPLDEKEAAQWLHKLYQEKDALQEIYNQKGMFPGEQFKPARRPWTLLNFLSWATILLSPLFSFVLGVFASGSPLLILTFLGFVGAASFGVRRLIGVTEIEKGSSYGNQEFKKKE", "length": 376 }, "evidence": [ { "id": "G5E5P6", "url": "https://omabrowser.org/oma/group/G5E5P6/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" } ], "go_annotation": { "categories": [ { "name": "Molecular Function", "total": 1, "go_terms": [ { "name": "1-acylglycerol-3-phosphate O-acyltransferase activity", "id": "GO:0003841", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003841", "evidence": [ { "database": "UniProtKB", "id": "G5E5P6", "url": "https://www.uniprot.org/uniprotkb/G5E5P6" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 4, "go_terms": [ { "name": "nuclear envelope", "id": "GO:0005635", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005635", "evidence": [ { "database": "UniProtKB", "id": "G5E5P6", "url": "https://www.uniprot.org/uniprotkb/G5E5P6" } ], "pmid": "" }, { "name": "endoplasmic reticulum", "id": "GO:0005783", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005783", "evidence": [ { "database": "UniProtKB", "id": "G5E5P6", "url": "https://www.uniprot.org/uniprotkb/G5E5P6" } ], "pmid": "" }, { "name": "endoplasmic reticulum membrane", "id": "GO:0005789", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005789", "evidence": [ { "database": "UniProtKB", "id": "G5E5P6", "url": "https://www.uniprot.org/uniprotkb/G5E5P6" } ], "pmid": "" }, { "name": "endomembrane system", "id": "GO:0012505", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0012505", "evidence": [ { "database": "UniProtKB", "id": "G5E5P6", "url": "https://www.uniprot.org/uniprotkb/G5E5P6" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 1, "go_terms": [ { "name": "phospholipid biosynthetic process", "id": "GO:0008654", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008654", "evidence": [ { "database": "UniProtKB", "id": "G5E5P6", "url": "https://www.uniprot.org/uniprotkb/G5E5P6" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [ { "pdb_id": "AF-G5E5P6-F1", "pdb_chain": "global", "start_pos": 1, "end_pos": 376, "overlap": "1.0", "method": "AlphaFold", "type": "alphafold", "resolution": -1.0, "url": "https://data.glygen.org/ln2downloads/pdb/current/AF-G5E5P6-F1.pdb", "url_external": "https://alphafold.ebi.ac.uk/entry/G5E5P6" } ], "lectin_list": [], "domain_list": [], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "homologset.oma", "label": "OMA Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ], "tool_support": { "graph_view": "yes" } }, { "uniprot_canonical_ac": "G5E5R1-1", "uniprot_ac": "G5E5R1", "uniprot_id": "G5E5R1_BOVIN", "mass": { "chemical_mass": 38548.0, "monoisotopic_mass": 38548.0 }, "refseq": { "ac": "XP_005228009", "name": "probable G-protein coupled receptor 174", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_005228009" }, "gene_names": [ { "name": "GPR174", "type": "recommended", "evidence": [ { "id": "G5E5R1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G5E5R1" } ] }, { "name": "GPR174", "type": "synonym", "evidence": [ { "id": "XP_005228009", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_005228009" } ] } ], "protein_names": [ { "name": "Probable G-protein coupled receptor 174", "type": "recommended", "evidence": [ { "id": "G5E5R1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G5E5R1/entry#names_and_taxonomy" } ] }, { "name": "probable G-protein coupled receptor 174", "type": "synonym", "evidence": [ { "id": "XP_005228009", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_005228009" } ] } ], "function": [], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Bos taurus", "taxid": 9913, "evidence": [ { "database": "UniProtKB", "id": "G5E5R1", "url": "https://www.uniprot.org/uniprotkb/G5E5R1" } ], "common_name": "Bovine", "glygen_name": "Bovine", "reference_species": "Bos taurus [9913]" } ], "gene": [ { "name": "GPR174", "url": "https://www.uniprot.org/uniprotkb/G5E5R1", "locus": { "chromosome": "X", "start_pos": 73131659, "end_pos": 73171519, "strand": "+", "evidence": [ { "database": "Ensembl Gene", "id": "ENSBTAG00000068926", "url": "https://www.ensembl.org/id/ENSBTAG00000068926" } ] } } ], "crossref": [ { "id": "ENSBTAG00000021437", "url": "https://bgee.org/?page=gene&gene_id=ENSBTAG00000021437", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "cd15152", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd15152", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "781056", "url": "https://www.ncbi.nlm.nih.gov/gene/781056", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR000276", "url": "https://www.ebi.ac.uk/interpro/entry/IPR000276", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR017452", "url": "https://www.ebi.ac.uk/interpro/entry/IPR017452", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR047836", "url": "https://www.ebi.ac.uk/interpro/entry/IPR047836", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "bta:781056", "url": "https://www.genome.jp/dbget-bin/www_bget?bta:781056", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "YLFLMHP", "url": "https://omabrowser.org/oma/group/YLFLMHP/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "G5E5R1", "url": "https://www.orthodb.org/?gene=G5E5R1", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR24232", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR24232", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR24232:SF86", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR24232:SF86", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00001", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00001", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "XP_005228009", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_005228009", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "G5E5R1", "url": "https://www.uniprot.org/uniprotkb/G5E5R1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "G5E5R1-1", "url": "https://www.uniprot.org/uniprotkb/G5E5R1-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MTANDTCAEINRDNTDSRYFIYAVTYTVILVPGLIGNILALWVFYGYMKETKRAVIFMINLAIADLLQVLSLPLRIFYYLNHDWPFGSGLCMFCFYLKYVNMYASIYFLVCISVRRFWFLLYPFRFHDCKQKYDLYISISGWLIICLACLLFPLLRSNDDTPSHRTKCFVDLPTRNVNLAQSVVMMTIGELIGFITPLLIVLFCTWKTVLSLQDKYPVAQDLGEKKKALKMILICAGVFLICFAPYHFSFPLDFLVKSNEIKSCLARRVILIFHSVALCLASLNSCLDPIIYYFTTDEFRRRLSRQELHDNIKLHAKSLVSNHTTSIVSTELC", "length": 333, "header": "tr|G5E5R1-1|G5E5R1_BOVIN Isoform 1 of Probable G-protein coupled receptor 174 OS=Bos taurus OX=9913 GN=GPR174 PE=4 SV=1 CANONICAL=G5E5R1-1" }, "isoforms": [ { "isoform_ac": "G5E5R1-1", "url": "https://www.uniprot.org/uniprotkb/G5E5R1/entry", "sequence": { "sequence": "MTANDTCAEINRDNTDSRYFIYAVTYTVILVPGLIGNILALWVFYGYMKETKRAVIFMINLAIADLLQVLSLPLRIFYYLNHDWPFGSGLCMFCFYLKYVNMYASIYFLVCISVRRFWFLLYPFRFHDCKQKYDLYISISGWLIICLACLLFPLLRSNDDTPSHRTKCFVDLPTRNVNLAQSVVMMTIGELIGFITPLLIVLFCTWKTVLSLQDKYPVAQDLGEKKKALKMILICAGVFLICFAPYHFSFPLDFLVKSNEIKSCLARRVILIFHSVALCLASLNSCLDPIIYYFTTDEFRRRLSRQELHDNIKLHAKSLVSNHTTSIVSTELC", "length": 333, "header": "tr|G5E5R1-1|G5E5R1_BOVIN Isoform 1 of Probable G-protein coupled receptor 174 OS=Bos taurus OX=9913 GN=GPR174 PE=4 SV=1 CANONICAL=G5E5R1-1" }, "locus": { "chromosome": "X", "start_pos": 73136025, "end_pos": 73135027, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000089101.2", "url": "https://www.ensembl.org/id/ENSBTAT00000089101.2" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000076514.1", "url": "https://www.ensembl.org/id/ENSBTAP00000076514.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [ { "id": "bta:781056", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?bta:781056", "resource": "KEGG Pathway" } ], "orthologs": [ { "uniprot_canonical_ac": "A0A9J7HA11-1", "protein_name": "Probable G-protein coupled receptor 174", "gene_name": "Gpr174", "tax_id": 10029, "organism": "Cricetulus griseus", "sequence": { "sequence": "MIDNYTCNKTEGDNIDFRYFIYAVTYTVILVPGLIGNILALWVFYGYMKETKRAVVFMINLAIADLLQILSLPLRIFYYLNHDWPFGPGLCMFCFYLKYVNMYASIYFLVCISVRRFWFLMYPFRFNDCKQKYDLYISIVGWLIICLACLLFPLLRTNDDTPGNRTKCFVDLPTRNVNLAQSVAMITIGELVGFVTPLMIVLYCTWKTALSLQNKYPISQHLGEKKKALKMILTCAGVFLICFAPYHFSFPLDFLVKSNEIKSCLARRVILIFHSVALCLASLNSCLDPIIYYFTTNEFRRRLSRQDLPESIQLHTKSYKIVSNHTTSTMGTDLC", "length": 335 }, "evidence": [ { "id": "G5E5R1", "url": "https://omabrowser.org/oma/group/G5E5R1/", "database": "OMA" } ], "glygen_name": "Hamster", "common_name": "Chinese hamster" }, { "uniprot_canonical_ac": "D3ZWS1-1", "protein_name": "Probable G-protein coupled receptor 174", "gene_name": "Gpr174", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MTDNFTCNKTDGDNTDFRYFIYAVTYTVILVPGLIGNILALWVFYGYMKETKRAVVFMINLAIADLLQILSLPLRIFYYLNHDWPFGPGLCMFCFYLKYVNMYASIYFLVCISVRRFWFLMYPFRFNDCKQKYDLYISIVGWLIICLACLLFPLLRTNDDTPGNRTKCFVDLPIRNVNLAQSVAMITIGEVVGFITPLMIVLYCTWKTALSLQNKYPISQHLGEKKKALRMILTCAAVFLICFAPYHFSFPLDFLVKSNEIKSCLARRVILIFHSVALCLASLNSCLDPVIYYFTTNEFRRRLSRQELPDSIQLQTKSYKIVNNHGASPTAAELC", "length": 335 }, "evidence": [ { "id": "G5E5R1", "url": "https://omabrowser.org/oma/group/G5E5R1/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "F1RPF4-1", "protein_name": "Probable G-protein coupled receptor 174", "gene_name": "GPR174", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MSANDTCPGTDGANTDFRYFIYAVTYTVILVPGLIGNILALWVFYGYMKETKRAVIFMINLAIADLLQVLSLPLRIFYYLNHDWPFGSGLCMFCFYLKYVNMYASIYFLVCISVRRFWFLLYPFRFHDCKQKYDLYISIVGWLIICLACLLFPLLRSSDDTPGNKTKCFVDLPTRNVNLAQSVVMMTIGELIGFVTPLLIVLYCTWKTVLSLQDKYPVAQDLGEKKKALKMILTCAGVFLICFAPYHFSFPLDFLVKSNEIKSCLARRVIIIFHSVALCLASLNSCLDPVIYYFTTNEFRRRLSRQDLHDNIKLHAKSFVSNHITSTLRNEVC", "length": 333 }, "evidence": [ { "id": "G5E5R1", "url": "https://omabrowser.org/oma/group/G5E5R1/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "Q3U507-1", "protein_name": "Probable G protein-coupled receptor 174", "gene_name": "Gpr174", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": 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[], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Bos taurus", "taxid": 9913, "evidence": [ { "database": "UniProtKB", "id": "G5E5S2", "url": "https://www.uniprot.org/uniprotkb/G5E5S2" } ], "common_name": "Bovine", "glygen_name": "Bovine", "reference_species": "Bos taurus [9913]" } ], "gene": [ { "name": "NELFB", "url": "https://www.uniprot.org/uniprotkb/G5E5S2", "locus": { "chromosome": "11", "start_pos": 106274375, "end_pos": 106266319, "strand": "-", "evidence": [ { "database": "Ensembl Gene", "id": "ENSBTAG00000021861", "url": "https://www.ensembl.org/id/ENSBTAG00000021861" } ] } } ], "crossref": [ { "id": "G5E5S2", "url": "https://alphafold.ebi.ac.uk/entry/G5E5S2", "database": "AlphaFoldDB", "categories": [] }, { "id": "ENSBTAG00000021861", "url": "https://bgee.org/?page=gene&gene_id=ENSBTAG00000021861", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "512799", "url": 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"https://www.uniprot.org/uniprotkb/G5E5S2", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "G5E5S2-1", "url": "https://www.uniprot.org/uniprotkb/G5E5S2-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MAELEGAGERSAGGPRGPGERTAAGPVASAAAPGERGGDGAPGRVGAGASALFAGLQDLGVANGEDLKETLTNCTEPLKAIEQFQTENGVLLPSLQSALPFLDLHGTPRLEFHQSVFDELRDKLLERVSAIASEGKAEERYKKLEDLLEKSFSLVKMPSLQPVVMCVMKHLPKVPEKKLKLVMADKELYRACAVEVKRQIWQDNQALFGDEVSPLLKQYIVEKESALFSTELSVLHNFFSPSPKTRRQGEVVQRLTRMVGRNVKLYDMVLQFLRTLFLRTRNVHYCTLRAELLMSLHDLDVGDICSVDPCHKFTWCLDACIRERFVDSKRARELQGFLDGVKKGQEQVLGDLSMILCDPFAINTLSLSTVRHLQELVGQEVLPRDSPDLLLLLRLLALGQGAWDMIDSQVFKEPKMEVELVTRFLPMLMSFVVDDHTFNVDQKLPAEEKAPVTYPNTLPESFTKFLQEQRMACEVGLYYVLHITKQRNKNALLRLLPGLVETFGDLAFGDIFLHLLTGSLALLADEFALEDFCSSLFDGFLLTASPRKESVQRHVLRLLLHLHHRVAPSKLEALQKALEPTGQSGEAVKELYSQLGEKLEQLDHRKPSPAQAPETPALELPLPAVPAPAVL", "length": 631, "header": "tr|G5E5S2-1|G5E5S2_BOVIN Isoform 1 of Negative elongation factor complex member B OS=Bos taurus OX=9913 GN=NELFB PE=4 SV=3 CANONICAL=G5E5S2-1" }, "isoforms": [ { "isoform_ac": "G5E5S2-1", "url": "https://www.uniprot.org/uniprotkb/G5E5S2/entry", "sequence": { "sequence": "MAELEGAGERSAGGPRGPGERTAAGPVASAAAPGERGGDGAPGRVGAGASALFAGLQDLGVANGEDLKETLTNCTEPLKAIEQFQTENGVLLPSLQSALPFLDLHGTPRLEFHQSVFDELRDKLLERVSAIASEGKAEERYKKLEDLLEKSFSLVKMPSLQPVVMCVMKHLPKVPEKKLKLVMADKELYRACAVEVKRQIWQDNQALFGDEVSPLLKQYIVEKESALFSTELSVLHNFFSPSPKTRRQGEVVQRLTRMVGRNVKLYDMVLQFLRTLFLRTRNVHYCTLRAELLMSLHDLDVGDICSVDPCHKFTWCLDACIRERFVDSKRARELQGFLDGVKKGQEQVLGDLSMILCDPFAINTLSLSTVRHLQELVGQEVLPRDSPDLLLLLRLLALGQGAWDMIDSQVFKEPKMEVELVTRFLPMLMSFVVDDHTFNVDQKLPAEEKAPVTYPNTLPESFTKFLQEQRMACEVGLYYVLHITKQRNKNALLRLLPGLVETFGDLAFGDIFLHLLTGSLALLADEFALEDFCSSLFDGFLLTASPRKESVQRHVLRLLLHLHHRVAPSKLEALQKALEPTGQSGEAVKELYSQLGEKLEQLDHRKPSPAQAPETPALELPLPAVPAPAVL", "length": 631, "header": "tr|G5E5S2-1|G5E5S2_BOVIN Isoform 1 of Negative elongation factor complex member B OS=Bos taurus OX=9913 GN=NELFB PE=4 SV=3 CANONICAL=G5E5S2-1" }, "locus": { "chromosome": "11", "start_pos": 106273662, "end_pos": 106266518, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000029144.7", "url": "https://www.ensembl.org/id/ENSBTAT00000029144.7" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000029144.6", "url": "https://www.ensembl.org/id/ENSBTAP00000029144.6" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [ { "id": "R-BTA-112382", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-BTA-112382", "resource": "Reactome", "description": "Formation of RNA Pol II elongation complex" }, { "id": "R-BTA-113418", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-BTA-113418", "resource": "Reactome", "description": "Formation of the Early Elongation Complex" }, { "id": "R-BTA-674695", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-BTA-674695", "resource": "Reactome", "description": "RNA Polymerase II Pre-transcription Events" }, { "id": "R-BTA-6796648", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-BTA-6796648", "resource": "Reactome", "description": "TP53 Regulates Transcription of DNA Repair Genes" }, { "id": "R-BTA-75955", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-BTA-75955", "resource": "Reactome", "description": "RNA Polymerase II Transcription Elongation" } ], "orthologs": [ { "uniprot_canonical_ac": "A0A287BM68-1", "protein_name": "Negative elongation factor complex member B", "gene_name": "NELFB", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MNHGVGRRRGSDLALLWLWRRLEATAPIRPPAWESPHAARVLEKTEKKKSKKSNKTHLAKMFLLKPTKQADPAGDAPPAGVPEHPARGSSGPRGRTCLRPQAPRRWAGPRRGRGHAGRGGASSGACATSGRRLRAGSLPGAGRGSASRNLCAAAAAFPGSRLAGGPGCAGRKWAAAVQAEPRCGRDLAELEGAGERSSGGPRGPGERAAAGPAATGSAPGERGGDGAPSRVGAGASAMFAGLQDLGVANGEDLKETLTNCTEPLKAIEQFQTENGVLLPSLQSALPFLDLHGTPRLEFHQSVFDELRDKLLERVSAIASEGKAEERYKKLEELLEKSFSLVKMPSLQPVVMCVMKHLPKVPEKKLKLVMADKELYRACAVEVKRQIWQDNQALFGDEVSPLLKQYIVEKENALFSPELSVLHNFFSPSPKTRRQGEVVQKLTRMVGRNVKLYDMVLQFLRTLFLRTRNVHYCTLRAELLMSLHDLDVGDICSVDPCHKFTWCLDACIRERFVDGKRARELQGFLDGVKKGQEQVLGDLSMILCDPFAINTLSLSTVRHLQELVGQEMLPRESPDLLLLLRLLALGQGAWDMIDSQVFKEPKMEVELVTRFLPTLMSFVVDDHTFNVDQKLPAEEKAPVTYPSTLPESFTKFLQEQRMACEVGLYYVLHITKQRNKNALLRLLPGLVETFGDLAFSDIFLHLLTGNLALLADEFALEDFCSSLFDGFLLTASPRKENVQRHVLRLLIHLHQRVAPSKLEALQKALEPTGQSGEAVKELYSQLGEKLEQLDHRKPSPAQAAETPALELPLPAVPAPAVL", "length": 817 }, "evidence": [ { "id": "G5E5S2", "url": "https://omabrowser.org/oma/group/G5E5S2/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "D4ACV0-1", "protein_name": "Negative elongation factor complex member B", "gene_name": "Nelfb", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MATLEAAGERGLGGPRGTVERTSGAPSASATAPAERGGDGVHSRAAVGASAMFAGLQDLGVANGEDLKETLTNCTEPLKAIEQFQTENGVLLPSLQSALPFLDLHGTPRLEFHQSVFDELRDKLLERVSAIASEGKAEERYKKLEDLLEKSFSLVKMPSLQPVVMCVMKHLPKVPEKKLKLVMADKELYRACAVEVKRQIWQDNQALFGDEVSPLLKQYILEKESALFSTELSVLHNFFSPSPKTRRQGEVVQKLTQMVGKNVKLYDMVLQFLRTLFLRTRNVHYCTLRAELLMSLHDLDVSDICTVDPCHKFTWCLDACIRERFVDSKRARELQGFLDGVKKGQEQVLGDLSMILCDPFAINTLSLSTIRHLQELVSQETLPRDSPDLLLLLRLLALGQGAWDLIDSQVFKEPKMEAELITKFLPMLMSFVVDDYTFNVDQKLPAEEKAPVTYPNTLPESFTKFLQEQRMACEVGLYYVLHITKQRNKNALLRLLPGLVETFGDLAFSDIFLHLLTGSLALLADEFALEDFCSSLFDGFFLTASPRKDNVHRHVLRLLLHLHARVAPSKLEALQKALEPTGQSGEAVKELYSQLGEKLEQLDHRKPSPPQAAETPALELPLPSVPAPAAL", "length": 631 }, "evidence": [ { "id": "G5E5S2", "url": "https://omabrowser.org/oma/group/G5E5S2/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, 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"uniprot_canonical_ac": "Q8WX92-2", "protein_name": "Negative elongation factor B", "gene_name": "NELFB", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MAELEGAGERGSGGPRGPAERASGVSAAAPGERAGDGAPSRAVAGASAMFAGLQDLGVANGEDLKETLTNCTEPLKAIEQFQTENGVLLPSLQSALPFLDLHGTPRLEFHQSVFDELRDKLLERVSAIASEGKAEERYKKLEDLLEKSFSLVKMPSLQPVVMCVMKHLPKVPEKKLKLVMADKELYRACAVEVKRQIWQDNQALFGDEVSPLLKQYILEKESALFSTELSVLHNFFSPSPKTRRQGEVVQRLTRMVGKNVKLYDMVLQFLRTLFLRTRNVHYCTLRAELLMSLHDLDVGEICTVDPCHKFTWCLDACIRERFVDSKRARELQGFLDGVKKGQEQVLGDLSMILCDPFAINTLALSTVRHLQELVGQETLPRDSPDLLLLLRLLALGQGAWDMIDSQVFKEPKMEVELITRFLPMLMSFLVDDYTFNVDQKLPAEEKAPVSYPNTLPESFTKFLQEQRMACEVGLYYVLHITKQRNKNALLRLLPGLVETFGDLAFGDIFLHLLTGNLALLADEFALEDFCSSLFDGFFLTASPRKENVHRHALRLLIHLHPRVAPSKLEALQKALEPTGQSGEAVKELYSQLGEKLEQLDHRKPSPAQAAETPALELPLPSVPAPAPL", "length": 628 }, "evidence": [ { "id": "G5E5S2", "url": "https://omabrowser.org/oma/group/G5E5S2/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "Q9Y113-1", "protein_name": "Negative elongation factor B", "gene_name": "NELF-B", "tax_id": 7227, "organism": "Drosophila melanogaster", "sequence": { "sequence": "MIMSTPAKNNNGTGLEDVNIPGQAYLREALTSCTDPLKAIESFQLENGVLLPSLRPMLPLLDLHGVRRLDFHTSLMEELRDKLIAHINEMGQKEPRERDKKLKELLVKSFPVVRVKSLRPVVMAILRNTQHIDDKYLKILVRDRELYADTDTEVKRQIWRDNQSLFGDEVSPLLSQYIREKEHILFDHTNLNNLFFHPTPKVRRQGEVVQKLANMIGTSVKLYDMVLQFLRTLFLRTRNVHYCTLRAELLMALHDLEVQEIISIDPCHKFTWCLDACIREKNVDIKRSRELQGFLDNIKRGQEQVLGDLSMTLCDPYAINFLATSAIKILHHLINNEGMPRDNQILILLLRMLALGLSAWVMIDSQDFKEPKLDCQVVTKFLPALMSLMVDDQCRSLHAKLPPDERESALTTIEHSGPAPDAVEAYIQESSVASILAMYYTLHTARLKDRVGVLRVLAILSACKDDRAYEDPFLHSLIALLIPMSEEFATEDFCTTLFDEFIFAGLTRENVTSRHMLKLLWYVHNKLPAGRLATLMKAMQPTTAHNEHIHKLYEILQERIGTGAAETPVIEAPPMEFDSPLKSVPTPGPHYNVQ", "length": 594 }, "evidence": [ { "id": "G5E5S2", "url": "https://omabrowser.org/oma/group/G5E5S2/", "database": "OMA" } ], "glygen_name": "Fruit fly", "common_name": "Fruit fly" } ], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 2, "go_terms": [ { "name": "cytoplasm", "id": "GO:0005737", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005737", "evidence": [ { "database": "UniProtKB", "id": "G5E5S2", "url": "https://www.uniprot.org/uniprotkb/G5E5S2" } ], "pmid": "" }, { "name": "NELF complex", "id": "GO:0032021", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0032021", "evidence": [ { "database": "UniProtKB", "id": "G5E5S2", "url": "https://www.uniprot.org/uniprotkb/G5E5S2" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 5, "go_terms": [ { "name": "cell population proliferation", "id": "GO:0008283", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008283", "evidence": [ { "database": "UniProtKB", "id": "G5E5S2", "url": "https://www.uniprot.org/uniprotkb/G5E5S2" } ], "pmid": "" }, { "name": "stem cell differentiation", "id": "GO:0048863", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0048863", "evidence": [ { "database": "UniProtKB", "id": "G5E5S2", "url": "https://www.uniprot.org/uniprotkb/G5E5S2" } ], "pmid": "" }, { "name": "negative regulation of transcription elongation by RNA polymerase II", "id": "GO:0034244", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0034244", "evidence": [ { "database": "UniProtKB", "id": "G5E5S2", "url": "https://www.uniprot.org/uniprotkb/G5E5S2" } ], "pmid": "" }, { "name": "negative regulation of stem cell differentiation", "id": "GO:2000737", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:2000737", "evidence": [ { "database": "UniProtKB", "id": "G5E5S2", "url": "https://www.uniprot.org/uniprotkb/G5E5S2" } ], "pmid": "" }, { "name": "transcription pausing by RNA polymerase II", "id": "GO:0160239", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0160239", "evidence": [ { "database": "UniProtKB", "id": "G5E5S2", "url": "https://www.uniprot.org/uniprotkb/G5E5S2" } ], "pmid": "" } ] }, { "name": "Molecular Function", "total": 1, "go_terms": [ { "name": "RNA polymerase inhibitor activity", "id": "GO:0140870", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0140870", "evidence": [ { "database": "UniProtKB", "id": "G5E5S2", "url": "https://www.uniprot.org/uniprotkb/G5E5S2" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 73, "end_pos": 75, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [ { "pdb_id": "AF-G5E5S2-F1", "pdb_chain": "global", "start_pos": 1, "end_pos": 631, "overlap": "1.0", "method": "AlphaFold", "type": "alphafold", "resolution": -1.0, "url": "https://data.glygen.org/ln2downloads/pdb/current/AF-G5E5S2-F1.pdb", "url_external": "https://alphafold.ebi.ac.uk/entry/G5E5S2" } ], "lectin_list": [], "domain_list": [], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "homologset.oma", "label": "OMA Homologs" } ], "sequence_features": { 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"table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ], "tool_support": { "graph_view": "yes" } }, { "uniprot_canonical_ac": "G5E5V6-1", "uniprot_ac": "G5E5V6", "uniprot_id": "G5E5V6_BOVIN", "mass": { "chemical_mass": 147931.0, "monoisotopic_mass": 147931.0 }, "refseq": { "ac": "XP_003586618", "name": "cingulin-like protein 1", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_003586618" }, "gene_names": [ { "name": "CGNL1", "type": "recommended", "evidence": [ { "id": "G5E5V6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G5E5V6" } ] }, { "name": "CGNL1", "type": "synonym", "evidence": [ { "id": "XP_003586618", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_003586618" } ] } ], "protein_names": [ { "name": "Cingulin like 1", "type": "synonym", "evidence": [ { "id": "G5E5V6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G5E5V6/entry#names_and_taxonomy" } ] }, { "name": "cingulin-like protein 1", "type": "synonym", "evidence": [ { "id": "XP_003586618", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_003586618" } ] } ], "function": [], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Bos taurus", "taxid": 9913, "evidence": [ { "database": "UniProtKB", "id": "G5E5V6", "url": "https://www.uniprot.org/uniprotkb/G5E5V6" } ], "common_name": "Bovine", "glygen_name": "Bovine", "reference_species": "Bos taurus [9913]" } ], "gene": [ { "name": "CGNL1", "url": "https://www.uniprot.org/uniprotkb/G5E5V6", "locus": { "chromosome": "10", "start_pos": 52768467, "end_pos": 52936994, "strand": "+", "evidence": [ { "database": "Ensembl Gene", "id": "ENSBTAG00000008575", "url": "https://www.ensembl.org/id/ENSBTAG00000008575" } ] } } ], "crossref": [ { "id": "ENSBTAG00000008575", "url": "https://bgee.org/?page=gene&gene_id=ENSBTAG00000008575", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "517509", "url": "https://www.ncbi.nlm.nih.gov/gene/517509", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR002928", "url": "https://www.ebi.ac.uk/interpro/entry/IPR002928", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "bta:517509", "url": "https://www.genome.jp/dbget-bin/www_bget?bta:517509", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "SEQNQVG", "url": "https://omabrowser.org/oma/group/SEQNQVG/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "G5E5V6", "url": "https://www.orthodb.org/?gene=G5E5V6", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR46349", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR46349", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR46349:SF2", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR46349:SF2", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF01576", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF01576", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "XP_003586618", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_003586618", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "G5E5V6", "url": "https://www.uniprot.org/uniprotkb/G5E5V6", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "G5E5V6-1", "url": "https://www.uniprot.org/uniprotkb/G5E5V6-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MELYFGEYQHVQQEYGVHLRLASDETRKSRNSQHAKAGSYGVSIRVQGIDGHPYIVLNNTEQCLAGTSFSENGPSFPAPMINNLPLHPSKGSVVEESSAEELQLPENPYAPPGPVRNLKQPSVFEGKNGALERKEEPRKASPMLNFERHPELLQPYDPEKNELSLKNHQPPETSWLKALREGTNNKKAWTCMPKPSLSQPTSPPSEDPARSNVTAIRLCSSVVIDDPKKQTSVCMNVQSCSKECLAEEALAPSGRPLPTPSLQAHLEAKKTRPDVLPFRRQDSAGPVLDGARSRRSSSSSTTPTSANSLYRFLLDDQECAIHADNVNRHENRRYIPFLPGTGRDIDTGSIPGVDQLIEKFDQKPGMQRRGRSGKRNRINPEDRKRSRSVDSAFPFGLQGNSEYLTEFSRNLGKSSEHLLRPSQVCPPRAQEHRGRQGGGRAFARLLGAQPRPPLQNKDGKVPENKSAQESPTGRTSSLPAQTKKEEEIKTVTATLMLQNPALATSPDSGTKRISVKTFTSTSNTQATPDLLKGQQELTQQTNEETAKQILYNYLKEGSTDNDDATKRKVNLVFEKIQTLKSRAAGSTQGNNQASNSSSEVKDLLEQKNKLTTEVAELQTQLQLEVKNQQNIKEERDRMKADLEVLQSQHDSKVEESTVLQRRLEESEGALRRHLEELFQVKMEREQHQTEIRDLQDQLSEMHDELDSAKQSEDREKGALIEELLQAKQDLQHLLIAKEEQEDLLRKRERELTALKGALKEEVSSHDREMDKLKEQYDAELLALRESVEEATKNVEVLASRSSSAEQTQVGAEMRVKALQEENEKLRGSVEELERTVARLQRQLADLQDDEAKAKETLKKCEGETRQLEEALLHARKEEKEATSAKRALQTELEEAQRNLSRATQEQKQLSERLKDEAEQKEQLRRLKNEMENERWHLDKTIEKLQKEMADIVEVSRTSTLELQNQLDEYKEKNRRELAEMQRQLKEKTLEAEKSHLTAMKLQDEMRLMEEELRDYQRAQEEALTKRQLLEQTLKDLEYELEAKSHLKDDRGRLVKQMEDKVSQLEMELEEERNNSDLLSERITRSREQMEQMRNELLQERAMKQDLECDKISLERQNKDLKSRIIHLEGSYRSSKEGLVVQMEARIAELEDRLESEERDRASLQLSNRRLERKVKELVMQVDDEHLSLTDQKDQLSLRLKAMKRQVEEAEEEIDRLESSKKKLQRELEEQMDVNEQLQGQLNSMKKDLRLKKLPSKVLDDVDDDDDLSTDGGSLYEAPLSYTFPKDSTVVSQI", "length": 1293, "header": "tr|G5E5V6-1|G5E5V6_BOVIN Isoform 1 of Cingulin like 1 OS=Bos taurus OX=9913 GN=CGNL1 PE=4 SV=1 CANONICAL=G5E5V6-1" }, "isoforms": [ { "isoform_ac": "G5E5V6-1", "url": "https://www.uniprot.org/uniprotkb/G5E5V6/entry", "sequence": { "sequence": "MELYFGEYQHVQQEYGVHLRLASDETRKSRNSQHAKAGSYGVSIRVQGIDGHPYIVLNNTEQCLAGTSFSENGPSFPAPMINNLPLHPSKGSVVEESSAEELQLPENPYAPPGPVRNLKQPSVFEGKNGALERKEEPRKASPMLNFERHPELLQPYDPEKNELSLKNHQPPETSWLKALREGTNNKKAWTCMPKPSLSQPTSPPSEDPARSNVTAIRLCSSVVIDDPKKQTSVCMNVQSCSKECLAEEALAPSGRPLPTPSLQAHLEAKKTRPDVLPFRRQDSAGPVLDGARSRRSSSSSTTPTSANSLYRFLLDDQECAIHADNVNRHENRRYIPFLPGTGRDIDTGSIPGVDQLIEKFDQKPGMQRRGRSGKRNRINPEDRKRSRSVDSAFPFGLQGNSEYLTEFSRNLGKSSEHLLRPSQVCPPRAQEHRGRQGGGRAFARLLGAQPRPPLQNKDGKVPENKSAQESPTGRTSSLPAQTKKEEEIKTVTATLMLQNPALATSPDSGTKRISVKTFTSTSNTQATPDLLKGQQELTQQTNEETAKQILYNYLKEGSTDNDDATKRKVNLVFEKIQTLKSRAAGSTQGNNQASNSSSEVKDLLEQKNKLTTEVAELQTQLQLEVKNQQNIKEERDRMKADLEVLQSQHDSKVEESTVLQRRLEESEGALRRHLEELFQVKMEREQHQTEIRDLQDQLSEMHDELDSAKQSEDREKGALIEELLQAKQDLQHLLIAKEEQEDLLRKRERELTALKGALKEEVSSHDREMDKLKEQYDAELLALRESVEEATKNVEVLASRSSSAEQTQVGAEMRVKALQEENEKLRGSVEELERTVARLQRQLADLQDDEAKAKETLKKCEGETRQLEEALLHARKEEKEATSAKRALQTELEEAQRNLSRATQEQKQLSERLKDEAEQKEQLRRLKNEMENERWHLDKTIEKLQKEMADIVEVSRTSTLELQNQLDEYKEKNRRELAEMQRQLKEKTLEAEKSHLTAMKLQDEMRLMEEELRDYQRAQEEALTKRQLLEQTLKDLEYELEAKSHLKDDRGRLVKQMEDKVSQLEMELEEERNNSDLLSERITRSREQMEQMRNELLQERAMKQDLECDKISLERQNKDLKSRIIHLEGSYRSSKEGLVVQMEARIAELEDRLESEERDRASLQLSNRRLERKVKELVMQVDDEHLSLTDQKDQLSLRLKAMKRQVEEAEEEIDRLESSKKKLQRELEEQMDVNEQLQGQLNSMKKDLRLKKLPSKVLDDVDDDDDLSTDGGSLYEAPLSYTFPKDSTVVSQI", "length": 1293, "header": "tr|G5E5V6-1|G5E5V6_BOVIN Isoform 1 of Cingulin like 1 OS=Bos taurus OX=9913 GN=CGNL1 PE=4 SV=1 CANONICAL=G5E5V6-1" }, "locus": { "chromosome": "10", "start_pos": 52876173, "end_pos": 52769471, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000035934.5", "url": "https://www.ensembl.org/id/ENSBTAT00000035934.5" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000035800.3", "url": "https://www.ensembl.org/id/ENSBTAP00000035800.3" } ] } } ], "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "other", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 259, "start_aa": "Thr", "end_pos": 259, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr259", "evidence": [ { "id": "", "database": "GlyGen", "url": "https://data.glygen.org/" } ], "filter_code": "000000000000000010000.00000000001000.0.01000" } ], "phosphorylation": [], "glycation": [], "keywords": [ "glycoprotein", "glycoprotein_predicted" ], "publication": [], "pathway": [ { "id": "bta:517509", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?bta:517509", "resource": "KEGG Pathway" } ], "orthologs": [ { "uniprot_canonical_ac": "A0A286ZRZ8-1", "protein_name": "Cingulin like 1", "gene_name": "CGNL1", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MELYFGEYQHVQQEYGVHLRLASDESKKPRNSQHAKTGSYGVSIRVQGIDGHPYIVLNNTERCLAGASLSENGPSFPPPMINNLPLHSNNGSVLEENSAEELQLPENPYAQPSPVRNLKQSSLLEGKNGVLERKEQLVKPSPVLNFQRHPELLQPYDPEKNEWHLQNHQPPESSWLKALTEEGTNNKKAWTCLSKPSRLQPTSPPLEDPAKSSVTAIRLCSSVVIDDPKKQTSVCVNVQSCSKEVEEALSPGGRPLPTHGPHTHPEAKKTRPDVLPFRRQDSAGPVLDGARSRRSSSSSTTPTSANSLYRFLLDDQECAIHADNVNRHENRRYIPFLPGTGRDIDTGSIPGVDQLIEKFDQKSGLQRRGRSGKRNRINPEDRKRSRSVDSAFPFGLQGNSEYLSEFSRNLGKSTEHLLRPSQVCPPRAQAQEQRGKQGMGRAFARLQGAQPGLSPQNKDGQVPENRGGPESPTVRTSSLPAQNKKEEEIKTATATLMLQSRPLATSPDSGTKRISVKTFTSASNTQATPDLLKGQQELTQQTNEETAKQILYNYLKEGSTDNDDATKRKVNLVFEKIQTLKSRAAGSTQGNNQASNSSSEVKDLLEQKNKLTSEVAELQRQLQLEVKNQQNIREERERMKANLEALQSQHKGKVEENAELQRRLEESEGELRRQLEELFQVKMEREQHQTEIRDLQDQLSEMHDELDSAKRSEDREKGALIEELLQAKQDLQDLLIAKEEQEDLLRKRERELTALKGALKEEVSSHDLEMDKLKEQYDAELQALRESVEEATKNVEVLASRSSTAEQTQVGAEMHVKALQEENQKLRASIEELECTVARLQRQVADLQGDEAKAKEMLKKFEGENRQLEEALVRARKEEKEATSARRTLESELEDAQRNLSRATQEQKQMSEKLKDEAEQKEQLRRLKNEMENERWHLDKTIEKLQKEMADIVEVSRTSTLELQNQLDEYKEKNRRELAEMQRQLKEKTLEAEKSRLNAVKMQDEMRLLEEELRDYQRAQEEALTKRQLLEQTLKDLEYELEAKSHLKDDRGRLVKQMEDKMSQLELELDEERNNSDLLSERIARSREQMEQMRNELLQERAARQDLECDKISLERQTKDLKSRIIHLEGSYRSSKEGLVVQMEARIAELEDRLESEERDRASLQLSNRRLERKVKELVMQVDDEHLSLTDQKDQLSLRLKAMKRQVEEAEEEIDRLESSKKKLQRELEEQMDVNEQLQGQLNSMKKDLRLKKLPSKVLDDVDDDDDLSTDGGSLYEAPLSYTYPKDSTLASQI", "length": 1294 }, "evidence": [ { "id": "G5E5V6", "url": "https://omabrowser.org/oma/group/G5E5V6/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "A0A8C2LR12-1", "protein_name": "Cingulin-like protein 1", "gene_name": "Cgnl1", "tax_id": 10029, "organism": "Cricetulus griseus", "sequence": { "sequence": "MELYFGEYQHVQQEYGVHLRLASDEAQKPRNSQPSKAGSYGVSIRVQGIDGHPYIVLNNTERCLAGTPFPENGPAFASSMINNLSLHPSNGTVLKENNPEELQLPENPYLQTSPIRNQKQPLLHEGRNGVVERKDGPTKLPHVLNFQRHPELLQPYDPEKNEVTSKKHHPPESPWLRNAVEEGTNYKKPRNCFPKLCGSQPNSPTLEDVAKTNTMAIRLCSSVVIEDPQKQTSVCVNVQSCAKEGVGEETLSPPRKSPTAPSPQAYSETKKSRPDVLPFRRQDSAGPILDGARSRRSSSSSTTPTSATSLYRFLLDDQECAIHADNVNRHENRRYIPFLPGTGRDIDTCSIPGVDQLIEKFDQKPGLQRRGRSGKRNRINPEDRKRSRSVDSAFPFGLQGNTEYLTEFSRNLGKSSEHLLRPSQVFPQRSLAPEHRGKHSPSCTLARLQGATQGAHPKPPLQNKDGKVLNKGSQESGVACASSLPAQNKKEEEIKIATATLMLQNRAVAATPDSGAKKISVKTFPSDTNTQATPDLLKGQQELTQQTNEETAKQILYNYLKEGSTDNEDATKRKVNLVFEKIQTLKSRAAGSAQGNNQASNFSSEVKDLLEQKNKLILEVSELQRQLQLEVKNHQNIKEERERMREDLEELRGRHQSQMEETATLQRRLEESEGELRKNLEELFQVKMEREQHQTEIRDLQDQLSEMHDELDSTKQSEDREKGALIEELLQAKRDLQDLLIAKEEQEDLLRKRERELTALKGALKEEVSSHDQEMDRLKEQYDAELQALRESVEEATKNVEVLASRSNSSEQSQGEADLREKVLKEENEKLQARIAELERRLAQLQRQMEDVKDDEAQAKETLRKFESEVQQLERALVHARQEEKEATSARRALEKELEHAQRELSQTSQEQKELLEKLQEETGQKEQLQKLKNEMESERWHLDKTIEKLQKEMSDIAEASRTSSLQLQRQLGEYKEKNRRELAEMQNQLKEKSLEVEKAKLAAVKMQDELRLKEEELRDYQRAENEALTKRQLLEQSLKDLEYELEAKSHLKDDRSRLIKQMEDKVSQLEIELEEERTNADLLSERIAWSREQMEQMRSELLQEKAAKQDLECDKISLERQNKDLKSRIVHLEGSYRSSKEGLVVQMEARIAELEDRLENEERDRANLQLNNRRLERKVKELVMQVDDEHLSLTDQKDQLSLRLKAMKRQVEEAEEEIDRLESSKKKLQRELEDQIGVNEQLQGQLNSMKKGLRLKTLPSKVLDDSDDDDLSSDGGSLYEAPLSYSFPKDSTLTSQI", "length": 1298 }, "evidence": [ { "id": "G5E5V6", "url": "https://omabrowser.org/oma/group/G5E5V6/", "database": "OMA" } ], "glygen_name": "Hamster", "common_name": "Chinese hamster" }, { "uniprot_canonical_ac": "A0ABK0LKA5-1", "protein_name": "Cingulin-like 1", "gene_name": "Cgnl1", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MELYFGEYQHVQQEYGVHLRLASDGTPKPRNSQPSKAGSYGVSIRVQGIDGHPYIVLNNTERCLAGIPFPENRPFPSPMINNLSLHPSNGTVLKENTPEELQLPENPYLQASPVSGQKQFSFHEGRNGVLERKDGPTKLPHVLNFQRHPELLQPYDPEKNEVNSKKHHPPESPWLRNATEEGTNCKMSRNCFPKPCGSQPNSPTPEDLAKTNMTAIRLCSSVVIEDPQKQTSVCVNVQRCAKEGVGEETLSPRRKSPTAPSPQAYSETKKSRPDVLPFRRQDSAGPILDGARSRRSSSSSTTPTSATSLYKFLLDDQECAIHADSVNRHENRRYIPFLPGTGRDIDTCSIPGVDQLIEKFDQKPGQRRGRSGRRNRINADDRKRSRSVDSAFPFGLQGNTEYLTEFSRNLGKSSEHLLRPSQVFLQRSVAQEHRGKHSPISTLAKLQGAHPKPPLQNKDGKVLNKGSQESIGAGAPSLPAQNKKEEEIKIATATLMLQNRAVAATSDSGAKKISVKTFPSDSSTQVTATPDLLKGQQELTQQTNEETAKQILYNYLREGGTDNEDATKRKVNLVFEKIQTLKSRATGSAQGNNQAPNSSSEGNDLLDQKNKLILEVSELQQQLQLEMKNHQNIKEERERMREDLEELRVRHQSQVEETATLQRRLEESEEELRKNLEELFQVKIEREQHQTEIRDLQDQLSEMHDELDSTKRSEDQEKGALIEELLQAKQDLQDLLIAKEEQEDLLRKRERELTALKGALKEEVSSHDQEMDKLKEQYDAELQALRESVEEATKNVEVLASRSHSSEQTQAEADLREKALKEENEKLQGRIVELERRAAQLQRQMEDVKGDEAQAKETLRKCESEVQQLEEALVCARNEEKEAACARTAVERELEQAQRELSQISQEQKELLEKLQEEVEQKEQLRKLKNEMESERWHLDKTIEKLQKEMADIAEASRTSSLELQKQLDEYKEKNRRELAEMQTQLKEKSLEVEKARLAASKMQDELRLKEEELRDYQRAEEEALTKRQLLEQSLKDLEYQLEAKSHLKDDRSRLVKQMEDKVSQLEIELEEERTNADLLSERITWSREQMEQMRSELLQEKAAKQDLECDKISLERQNKDLKSRITHLEGSYRSSKEGLVVQMEARIAELEDRLENEERDRANLQLNNRRLERKVKELVMQVDDEHLSLTDQKDQLSLRLKAMKRQVEEAEEEIDRLESSKKKLQRELEEQIGVNEQLQGQLNSMKKGLRLKTLSSKVLDDSDDDDLSSDAGSLYEAPLSYPFPKDSTITSQI", "length": 1294 }, "evidence": [ { "id": "G5E5V6", "url": "https://omabrowser.org/oma/group/G5E5V6/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "Q0VF96-1", "protein_name": "Cingulin-like protein 1", "gene_name": "CGNL1", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MELYFGEYQHVQQEYGVHLRLASDDTQKSRSSQNSKAGSYGVSIRVQGIDGHPYIVLNNTERCLAGTSFSENGPPFPPPVINNLPLHSSNGSVPKENSEELQLPENPYAQPSPIRNLKQPLLHEGKNGVLDRKDGSVKPSHLLNFQRHPELLQPYDPEKNELNLQNHQPSESNWLKTLTEEGINNKKPWTCFPKPSNSQPTSPSLEDPAKSGVTAIRLCSSVVIEDPKKQTSVCVNVQSCTKERVGEEALFTSGRPLTAHSPHAHPETKKTRPDVLPFRRQDSAGPVLDGARSRRSSSSSTTPTSANSLYRFLLDDQECAIHADNVNRHENRRYIPFLPGTGRDIDTGSIPGVDQLIEKFDQKPGLQRRGRSGKRNRINTDDRKRSRSVDSAFPFGLQGNSEYLIEFSRNLGKSSEHLLRPSQVCPQRPLSQERRGKQSVGRTFAKLQGAAHGASCAHSRPPQPNIDGKVLETEGSQESTVIRAPSLGAQSKKEEEVKTATATLMLQNRATATSPDSGAKKISVKTFPSASNTQATPDLLKGQQELTQQTNEETAKQILYNYLKEGSTDNDDATKRKVNLVFEKIQTLKSRAAGSAQGNNQACNSTSEVKDLLEQKSKLTIEVAELQRQLQLEVKNQQNIKEERERMRANLEELRSQHNEKVEENSTLQQRLEESEGELRKNLEELFQVKMEREQHQTEIRDLQDQLSEMHDELDSAKRSEDREKGALIEELLQAKQDLQDLLIAKEEQEDLLRKRERELTALKGALKEEVSSHDQEMDKLKEQYDAELQALRESVEEATKNVEVLASRSNTSEQDQAGTEMRVKLLQEENEKLQGRSEELERRVAQLQRQIEDLKGDEAKAKETLKKYEGEIRQLEEALVHARKEEKEAVSARRALENELEAAQGNLSQTTQEQKQLSEKLKEESEQKEQLRRLKNEMENERWHLGKTIEKLQKEMADIVEASRTSTLELQNQLDEYKEKNRRELAEMQRQLKEKTLEAEKSRLTAMKMQDEMRLMEEELRDYQRAQDEALTKRQLLEQTLKDLEYELEAKSHLKDDRSRLVKQMEDKVSQLEMELEEERNNSDLLSERISRSREQMEQLRNELLQERAARQDLECDKISLERQNKDLKSRIIHLEGSYRSSKEGLVVQMEARIAELEDRLESEERDRANLQLSNRRLERKVKELVMQVDDEHLSLTDQKDQLSLRLKAMKRQVEEAEEEIDRLESSKKKLQRELEEQMDMNEHLQGQLNSMKKDLRLKKLPSKVLDDMDDDDDLSTDGGSLYEAPVSYTFSKDSTVASQI", "length": 1302 }, "evidence": [ { "id": "G5E5V6", "url": "https://omabrowser.org/oma/group/G5E5V6/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "Q6AW69-4", "protein_name": "Cingulin-like protein 1", "gene_name": "Cgnl1", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MELYFGEYQHVQQEYGVHLRLASGDTPKPRNSQPSKAGSYGVSIRVQGIDGHPYIVLNNTERCLAGTPFPENAPSFPSSVINNLSLHPSNGTVLKENTPEELQLPENPYLQTSPLRGQKQFSLHEGRNGVLERKDGPTKLPHVLNFQRHPELLQPYDPEKNEVNAKKHHPPESPWLRNATEDGTNCKKSRNCFPKSYGSQPNSPTSEDLAKTNMTAIRLCSSVVIEDPQKQTSVCVNVQRCAKEGVGEETLSPRRKSPTAPSPQAYSETKKNRPDVLPFRRQDSAGPILDGARSRRSSSSSTTPTSATSLYKFLLDDQECAIHADSVNRHENRRYIPFLPGTGRDIDTCSIPGVDQLIEKFDQKPGLQRRGRSGKRNRINPDDRKRSRSVDSAFPFGLQGNTEYLTEFSRNLGKSSEHLLRPSQVFPQRSVAQEHRGKHSPSSPPAKLQGAQGAHPKPPLQNKDGKVLNKGRQESTGACAPSLPAPNKKEEEIKIATATLMLQNRAVAATSDSGAKKISVKTFPSDSSTQATPDLLKGQQELTQQTNEETAKQILYNYLKEGGTDNEDATKRKVNLVFEKIQTLKSRAAGSAQGSNQAPNSPSEGNSLLDQKNKLILEVSELQQQLQLEMKNQQNIKEERERMREDLEELRVRHQSQVEETATLQRRLEESEGELRKSLEELFQVKMEREQHQTEIRDLQDQLSEMHDELDSTKRSEDREKGALIEELLQAKQDLQDLLIAKEEQEDLLRKRERELTALKGALKEEVSSHDQEMDKLKEQYDAELQALRESVEEATKNVEVLASRSNSSEQSQAEADLREKVLKEENEKLQGRIAELERRAAQLQRQMEDVKGDEAQAKETLRKCESEVQQLEEALVHARKEEKEATCARRALEKELEQARRELSQVSQEQKELLEKLRDEAEQKEQLRKLKNEMESERWHLDKTIEKLQKEMADIAEASRTSSLELQKQLGEYKEKNRRELAEMQTQLKEKCLEVEKARLAASKMQDELRLKEEELQDYQRAEEEALTKRQLLEQSLKDLEYELEAKSHLKDDRSRLIKQMEDKVSQLEIELEEERTNADLLSERITWSREQMEQMRSELLQEKAAKQDLECDKISLERQNKDLKSRIIHLEGSYRSSKEGLVVQMEARIAELEDRLENEERDRANLQLSNRRLERKVKELVMQVDDEHLSLTDQKDQLSLRLKAMKRQVEEAEEEIDRLESSKKKLQRELEEQMGVNEQLQGQLNSLKKGLRLKTLSSKVLDDSDDDDLSSDAGSLYEAPLSYAFPKDSTIASQI", "length": 1297 }, "evidence": [ { "id": "G5E5V6", "url": "https://omabrowser.org/oma/group/G5E5V6/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" } ], "go_annotation": { "categories": [ { "name": "Biological Process", "total": 4, "go_terms": [ { "name": "protein localization to cell-cell junction", "id": "GO:0150105", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0150105", "evidence": [ { "database": "UniProtKB", "id": "G5E5V6", "url": "https://www.uniprot.org/uniprotkb/G5E5V6" } ], "pmid": "" }, { "name": "actin filament organization", "id": "GO:0007015", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007015", "evidence": [ { "database": "UniProtKB", "id": "G5E5V6", "url": "https://www.uniprot.org/uniprotkb/G5E5V6" } ], "pmid": "" }, { "name": "negative regulation of small GTPase mediated signal transduction", "id": "GO:0051058", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0051058", "evidence": [ { "database": "UniProtKB", "id": "G5E5V6", "url": "https://www.uniprot.org/uniprotkb/G5E5V6" } ], "pmid": "" }, { "name": "negative regulation of stress fiber assembly", "id": "GO:0051497", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0051497", "evidence": [ { "database": "UniProtKB", "id": "G5E5V6", "url": "https://www.uniprot.org/uniprotkb/G5E5V6" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 2, "go_terms": [ { "name": "bicellular tight junction", "id": "GO:0005923", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005923", "evidence": [ { "database": "UniProtKB", "id": "G5E5V6", "url": "https://www.uniprot.org/uniprotkb/G5E5V6" } ], "pmid": "" }, { "name": "myosin complex", "id": "GO:0016459", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016459", "evidence": [ { "database": "UniProtKB", "id": "G5E5V6", "url": "https://www.uniprot.org/uniprotkb/G5E5V6" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 1073, "end_pos": 1075, "annotation": "n_glycosylation_sequon" }, { "start_pos": 212, "end_pos": 214, "annotation": "n_glycosylation_sequon" }, { "start_pos": 464, "end_pos": 466, "annotation": "n_glycosylation_sequon" }, { "start_pos": 58, "end_pos": 60, "annotation": "n_glycosylation_sequon" }, { "start_pos": 595, "end_pos": 597, "annotation": "n_glycosylation_sequon" }, { "start_pos": 898, "end_pos": 900, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "homologset.oma", "label": "OMA Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [ 259 ], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 1073, "end_pos": 1075 }, { "start_pos": 212, "end_pos": 214 }, { "start_pos": 464, "end_pos": 466 }, { "start_pos": 58, "end_pos": 60 }, { "start_pos": 595, "end_pos": 597 }, { "start_pos": 898, "end_pos": 900 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 1 }, { "field": "total_sites", "count": 1 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 1 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "exact_sites", "count": 1 }, { "field": "exact_o_linked_sites", "count": 1 }, { "field": "fuzzy_sites", "count": 0 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_pos", "start_aa", "end_pos", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 1 }, { "field": "total_sites", "count": 1 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 1 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "exact_sites", "count": 1 }, { "field": "exact_o_linked_sites", "count": 1 }, { "field": "fuzzy_sites", "count": 0 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_pos", "start_aa", "end_pos", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ], "tool_support": { "graph_view": "yes" } }, { "uniprot_canonical_ac": "G3X7D0-1", "uniprot_ac": "G3X7D0", "uniprot_id": "G3X7D0_BOVIN", "mass": { "chemical_mass": 69760.0, "monoisotopic_mass": 69760.0 }, "refseq": {}, "gene_names": [ { "name": "TBL1X", "type": "recommended", "evidence": [ { "id": "G3X7D0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3X7D0" } ] } ], "protein_names": [ { "name": "Transducin beta like 1 X-linked", "type": "synonym", "evidence": [ { "id": "G3X7D0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3X7D0/entry#names_and_taxonomy" } ] } ], "function": [ { "annotation": "F-box-like protein involved in the recruitment of the ubiquitin/19S proteasome complex to nuclear receptor-regulated transcription units. Plays an essential role in transcription activation mediated by nuclear receptors. Probably acts as integral component of corepressor complexes that mediates the recruitment of the 19S proteasome complex, leading to the subsequent proteasomal degradation of transcription repressor complexes, thereby allowing cofactor exchange.", "evidence": [ { "database": "UniProtKB", "id": "B7TCI5", "url": "https://www.uniprot.org/uniprotkb/B7TCI5#function" }, { "database": "UniProtKB", "id": "ARBA00056890", "url": "https://www.uniprot.org/uniprotkb/ARBA00056890#function" }, { "database": "UniProtKB", "id": "G3X7D0", "url": "https://www.uniprot.org/uniprotkb/G3X7D0#function" }, { "database": "UniProtKB", "id": "A0ABI0NQH7", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NQH7#function" }, { "database": "UniProtKB", "id": "ARBA00058954", "url": "https://www.uniprot.org/uniprotkb/ARBA00058954#function" }, { "database": "UniProtKB", "id": "A0A3Q1NBK9", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1NBK9#function" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Bos taurus", "taxid": 9913, "evidence": [ { "database": "UniProtKB", "id": "G3X7D0", "url": "https://www.uniprot.org/uniprotkb/G3X7D0" } ], "common_name": "Bovine", "glygen_name": "Bovine", "reference_species": "Bos taurus [9913]" } ], "gene": [ { "name": "TBL1X", "url": "https://www.uniprot.org/uniprotkb/G3X7D0", "locus": { "chromosome": "X", "start_pos": 133339220, "end_pos": 133490275, "strand": "+", "evidence": [ { "database": "Ensembl Gene", "id": "ENSBTAG00000018112", "url": "https://www.ensembl.org/id/ENSBTAG00000018112" } ] } } ], "crossref": [ { "id": "G3X7D0", "url": "https://alphafold.ebi.ac.uk/entry/G3X7D0", "database": "AlphaFoldDB", "categories": [] }, { "id": "ENSBTAG00000018112", "url": "https://bgee.org/?page=gene&gene_id=ENSBTAG00000018112", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "cd00200", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd00200", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "515972", "url": "https://www.ncbi.nlm.nih.gov/gene/515972", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR001680", "url": "https://www.ebi.ac.uk/interpro/entry/IPR001680", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR006594", "url": "https://www.ebi.ac.uk/interpro/entry/IPR006594", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR015943", "url": "https://www.ebi.ac.uk/interpro/entry/IPR015943", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR019775", "url": "https://www.ebi.ac.uk/interpro/entry/IPR019775", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR020472", "url": "https://www.ebi.ac.uk/interpro/entry/IPR020472", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR036322", "url": "https://www.ebi.ac.uk/interpro/entry/IPR036322", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR045183", "url": "https://www.ebi.ac.uk/interpro/entry/IPR045183", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "bta:515972", "url": "https://www.genome.jp/dbget-bin/www_bget?bta:515972", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "KWNKCGN", "url": "https://omabrowser.org/oma/group/KWNKCGN/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "B7TCI5", "url": "https://www.orthodb.org/?gene=B7TCI5", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR22846", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR22846", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR22846:SF52", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR22846:SF52", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00400", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00400", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF08513", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF08513", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "R-BTA-3214815", "url": "https://www.reactome.org/PathwayBrowser/#R-BTA-3214815", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "R-BTA-350054", "url": "https://www.reactome.org/PathwayBrowser/#R-BTA-350054", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "R-BTA-400206", "url": "https://www.reactome.org/PathwayBrowser/#R-BTA-400206", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "R-BTA-9029569", "url": "https://www.reactome.org/PathwayBrowser/#R-BTA-9029569", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "R-BTA-9707564", "url": "https://www.reactome.org/PathwayBrowser/#R-BTA-9707564", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "R-BTA-9841922", "url": "https://www.reactome.org/PathwayBrowser/#R-BTA-9841922", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "A0A3Q1NBK9", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1NBK9", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A3Q1NBK9-1", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1NBK9-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0ABI0NQH7", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NQH7", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0ABI0NQH7-1", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NQH7-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "B7TCI5", "url": "https://www.uniprot.org/uniprotkb/B7TCI5", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "B7TCI5-1", "url": "https://www.uniprot.org/uniprotkb/B7TCI5-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "G3X7D0", "url": "https://www.uniprot.org/uniprotkb/G3X7D0", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "G3X7D0-1", "url": "https://www.uniprot.org/uniprotkb/G3X7D0-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MSITSDEVNFLVYRYLQESGFSHSAFTFGIESHISQSNINGTLVPPAALISILQKGLQYVEAEISINEDGTVFDGRPIESLSLIDAVMPDVVQTRQQAFREKLAQQQAAAAAAAAAAAAAAAAAATTAAPAAASQQNPPKNGEATVNGEENGAHAINNHSKPMEIDGDVEIPPSKATVLRGHESEVFICAWNPVSDLLASGSGDSTARIWNLNENSNGGSTQLVLRHCIREGGHDVPSNKDVTSLDWNSDGTLLATGSYDGFARIWTEDGNLASTLGQHKGPIFALKWNKKGNYILSAGVDKTTIIWDAHTGEAKQQFPFHSAPALDVDWQNNTTFASCSTDMCIHVCRLGCDRPVKTFQGHTNEVNAIKWDPSGMLLASCSDDMTLKIWSMKQDTCVHDLQAHSKEIYTIKWSPTGPATSNPNSSIMLASASFDSTVRLWDVERGVCLHTLTKHQEPVYSVAFSPDGKYLASGSFDKCVHIWNTQSGSLVHSYRGTGGIFEVCWNARGDKVGASASDGSFKTENTHASAVKGGEKEWFPPETSSPRGARSHQLDSVHGSIATQNRLRWLRRTKKQERLCQNEKRKKNAVINQKGRKNSSRQWVVFFCFFFSPKHLDTTVKLSQGCSKDQFVWMKWVPL", "length": 639, "header": "tr|G3X7D0-1|G3X7D0_BOVIN Isoform 1 of Transducin beta like 1 X-linked OS=Bos taurus OX=9913 GN=TBL1X PE=3 SV=2 CANONICAL=G3X7D0-1" }, "isoforms": [ { "isoform_ac": "A0A3Q1NBK9-1", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1NBK9/entry", "sequence": { "sequence": "MSITSDEVNFLVYRYLQESGFSHSAFTFGIESHISQSNINGTLVPPAALISILQKGLQYVEAEISINEDGTVFDGRPIESLSLIDAVMPDVVQTRQQAFREKLAQQQAAAAAAAAAAAAAAAAAATTAAPAAASQQNPPKNGEATVNGEENGAHAINNHSKPMEIDGDVEIPPSKATVLRGHESEVFICAWNPVSDLLASGSGDSTARIWNLNENSNGGSTQLVLRHCIREGGHDVPSNKDVTSLDWNSDGTLLATGSYDGFARIWTEDGNLASTLGQHKGPIFALKWNKKGNYILSAGVDKTTIIWDAHTGEAKQQFPFHSAPALDVDWQNNTTFASCSTDMCIHVCRLGCDRPVKTFQGHTNEVNAIKWDPSGMLLASCSDDMTLKIWSMKQDTCVHDLQAHSKEIYTIKWSPTGPATSNPNSSIMLASASFDSTVRLWDVERGVCLHTLTKHQEPVYSVAFSPDGKYLASGSFDKCVHIWNTQSGSLVHSYRGTGGIFEVCWNARGDKVGASVRVRSAKVNTHRKDIIDMRREFRRASSGCVGL", "length": 547, "header": "tr|A0A3Q1NBK9-1|G3X7D0_BOVIN Computationally mapped isoform of Transducin beta like 1 X-linked OS=Bos taurus OX=9913 GN=TBL1X PE=3 SV=2 CANONICAL=G3X7D0-1" }, "locus": { "chromosome": "X", "start_pos": 133399189, "end_pos": 133340497, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000084466.3", "url": "https://www.ensembl.org/id/ENSBTAT00000084466.3" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000068715.3", "url": "https://www.ensembl.org/id/ENSBTAP00000068715.3" } ] } }, { "isoform_ac": "A0ABI0NQH7-1", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NQH7/entry", "sequence": { "sequence": "MSITSDEVNFLVYRYLQESGFSHSAFTFGIESHISQSNINGTLVPPAALISILQKGLQYVEAEISINEDGTVFDGRPIESLSLIDAVMPDVVQTRQQAFREKLAQQQAAAAAAAAAAAAAAAAAATTAAPAAASQQNPPKNGEATVNGEENGAHAINNHSKPMEIDGDVEIPPSKATVLRGHESEVFICAWNPVSDLLASGSGDSTARIWNLNENSNGGSTQLVLRHCIREGGHDVPSNKDVTSLDWNSDGTLLATGSYDGFARIWTEDGNLASTLGQHKGPIFALKWNKKGNYILSAGVDKTTIIWDAHTGEAKQQFPFHSAPALDVDWQNNTTFASCSTDMCIHVCRLGCDRPVKTFQGHTNEVNAIKWDPSGMLLASCSDDMTLKRLVRFYRPPLGRGAGRVPPHADQAPGTRVQRGLQPRREVLGQRLLRQVCAHLEHSERKSRAQLPRHRGHLRGVLECPGRQSGRQCVRRLRVRVRSAKVNTHRKNIIDTRREFRRASSGCVGL", "length": 510, "header": "tr|A0ABI0NQH7-1|A0ABI0NQH7_BOVIN Computationally mapped isoform of F-box-like/WD repeat-containing protein TBL1XR1 OS=Bos taurus OX=9913 GN=TBL1X PE=3 SV=1 CANONICAL=G3X7D0-1" }, "locus": { "chromosome": "Y", "start_pos": 6781940, "end_pos": 6723314, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000148071.1", "url": "https://www.ensembl.org/id/ENSBTAT00000148071.1" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000104505.1", "url": "https://www.ensembl.org/id/ENSBTAP00000104505.1" } ] } }, { "isoform_ac": "B7TCI5-1", "url": "https://www.uniprot.org/uniprotkb/B7TCI5/entry", "sequence": { "sequence": "MSITSDEVNFLVYRYLQESGFSHSAFTFGIESHISQSNINGTLVPPAALISILQKGLQYVEAEISINEDGTVFDGRPIESLSLIDAVMPDVVQTRQQAFREKLAQQQAAAAAAAAAAAAAAAAAATTAAPAAASQQNPPKNGEATVNGEENGAHAINNHSKPMEIDGDVEIPPSKATVLRGHESEVFICAWNPVSDLLASGSGDSTARIWNLNENSNGGSTQLVLRHCIREGGHDVPSNKDVTSLDWNSDGTLLATGSYDGFARIWTEDGNLASTLGQHKGPIFALKWNKKGNYILSAGVDKTTIIWDAHTGEAKQQFPFHSAPALDVDWQNNTTFASCSTDMCIHVCRLGCDRPVKTFQGHTNEVNAIKWDPSGMLLASCSDDMTLKIWSMKQDTCVHDLQAHSKEIYTIKWSPTGPATSNPNSSIMLASASFDSTVRLWDVERGVCLHTLTKHQEPVYSVAFSPDGKYLASGSFDKCVHIWNTQSGSLVHSYRGTGGIFEVCWNARGDKVGASASDGSVCVLDLRK", "length": 528, "header": "tr|B7TCI5-1|B7TCI5_BOVIN Computationally mapped isoform of Transducin beta like 1 X-linked OS=Bos taurus OX=9913 GN=TBL1X PE=3 SV=1 CANONICAL=G3X7D0-1" }, "locus": { "chromosome": "X", "start_pos": 133399189, "end_pos": 133340571, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000074073.3", "url": "https://www.ensembl.org/id/ENSBTAT00000074073.3" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000073703.1", "url": "https://www.ensembl.org/id/ENSBTAP00000073703.1" } ] } }, { "isoform_ac": "G3X7D0-1", "url": "https://www.uniprot.org/uniprotkb/G3X7D0/entry", "sequence": { "sequence": "MSITSDEVNFLVYRYLQESGFSHSAFTFGIESHISQSNINGTLVPPAALISILQKGLQYVEAEISINEDGTVFDGRPIESLSLIDAVMPDVVQTRQQAFREKLAQQQAAAAAAAAAAAAAAAAAATTAAPAAASQQNPPKNGEATVNGEENGAHAINNHSKPMEIDGDVEIPPSKATVLRGHESEVFICAWNPVSDLLASGSGDSTARIWNLNENSNGGSTQLVLRHCIREGGHDVPSNKDVTSLDWNSDGTLLATGSYDGFARIWTEDGNLASTLGQHKGPIFALKWNKKGNYILSAGVDKTTIIWDAHTGEAKQQFPFHSAPALDVDWQNNTTFASCSTDMCIHVCRLGCDRPVKTFQGHTNEVNAIKWDPSGMLLASCSDDMTLKIWSMKQDTCVHDLQAHSKEIYTIKWSPTGPATSNPNSSIMLASASFDSTVRLWDVERGVCLHTLTKHQEPVYSVAFSPDGKYLASGSFDKCVHIWNTQSGSLVHSYRGTGGIFEVCWNARGDKVGASASDGSFKTENTHASAVKGGEKEWFPPETSSPRGARSHQLDSVHGSIATQNRLRWLRRTKKQERLCQNEKRKKNAVINQKGRKNSSRQWVVFFCFFFSPKHLDTTVKLSQGCSKDQFVWMKWVPL", "length": 639, "header": "tr|G3X7D0-1|G3X7D0_BOVIN Isoform 1 of Transducin beta like 1 X-linked OS=Bos taurus OX=9913 GN=TBL1X PE=3 SV=2 CANONICAL=G3X7D0-1" }, "locus": { "chromosome": "X", "start_pos": 133399189, "end_pos": 133339996, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000024105.8", "url": "https://www.ensembl.org/id/ENSBTAT00000024105.8" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000024105.7", "url": "https://www.ensembl.org/id/ENSBTAP00000024105.7" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [ { "id": "bta:515972", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?bta:515972", "resource": "KEGG Pathway" }, { "id": "R-BTA-3214815", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-BTA-3214815", "resource": "Reactome", "description": "HDACs deacetylate histones" }, { "id": "R-BTA-350054", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-BTA-350054", "resource": "Reactome", "description": "Notch-HLH transcription pathway" }, { "id": "R-BTA-400206", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-BTA-400206", "resource": "Reactome", "description": "Regulation of lipid metabolism by PPARalpha" }, { "id": "R-BTA-9029569", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-BTA-9029569", "resource": "Reactome", "description": "NR1H3 & NR1H2 regulate gene expression linked to cholesterol transport and efflux" }, { "id": "R-BTA-9707564", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-BTA-9707564", "resource": "Reactome", "description": "Cytoprotection by HMOX1" }, { "id": "R-BTA-9841922", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-BTA-9841922", "resource": "Reactome", "description": "MLL4 and MLL3 complexes regulate expression of PPARG target genes in adipogenesis and hepatic steatosis" } ], "orthologs": [ { "uniprot_canonical_ac": "A0A0G2JY80-1", "protein_name": "TBL1X/Y related 1", "gene_name": "Tbl1x", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MSITSDEVNFLVYRYLQESGFSHSAFTFGIESHISQSNINGTLVPPAALISILQKGLQYVEAEISINEDGTVFDGRPIESLSLIDAVMPDVVQTRQQAFREKLAQQQANAAAAAAAAAATATSTAATTPAAAAQQNPPKNGEATVNGEENGAHAINNHSKPMEIDGDVEIPPSKATVLRGHESEVFICAWNPVSDLLASGSGDSTARIWNLNENSNGGSTQLVLRHCIREGGHDVPSNKDVTSLDWNSDGTLLATGSYDGFARIWTEDGNLASTLGQHKGPIFALKWNKKGNYILSAGVDKTTIIWDAHTGEAKQQFPFHSAPALDVDWQNNTTFASCSTDMCIHVCRLGCDRPVKTFQGHTNEVNAIKWDPSGMLLASCSDDMTLKIWSMKQDACVHDLQAHSKEIYTIKWSPTGPATSNPNSNIMLASASFDSTVRLWDVERGVCIHTLTKHQEPVYSVAFSPDGKYLASGSFDKCVHIWNTQSGSLVHSYRGTGGIFEVCWNARGDKVGASASDGSVCVLDLRK", "length": 527 }, "evidence": [ { "id": "G3X7D0", "url": "https://omabrowser.org/oma/group/G3X7D0/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "P38262-1", "protein_name": "SIR4-interacting protein SIF2", "gene_name": "SIF2", "tax_id": 559292, "organism": "Saccharomyces cerevisiae S288C", "sequence": { "sequence": "MSITSEELNYLIWRYCQEMGHEVSALALQDETRVLEFDEKYKEHIPLGTLVNLVQRGILYTESELMVDSKGDISALNEHHLSEDFNLVQALQIDKEKFPEISSEGRFTLETNSESNKAGEDGASTVERETQEDDTNSIDSSDDLDGFVKILKEIVKLDNIVSSTWNPLDESILAYGEKNSVARLARIVETDQEGKKYWKLTIIAELRHPFALSASSGKTTNQVTCLAWSHDGNSIVTGVENGELRLWNKTGALLNVLNFHRAPIVSVKWNKDGTHIISMDVENVTILWNVISGTVMQHFELKETGGSSINAENHSGDGSLGVDVEWVDDDKFVIPGPKGAIFVYQITEKTPTGKLIGHHGPISVLEFNDTNKLLLSASDDGTLRIWHGGNGNSQNCFYGHSQSIVSASWVGDDKVISCSMDGSVRLWSLKQNTLLALSIVDGVPIFAGRISQDGQKYAVAFMDGQVNVYDLKKLNSKSRSLYGNRDGILNPLPIPLYASYQSSQDNDYIFDLSWNCAGNKISVAYSLQEGSVVAI", "length": 535 }, "evidence": [ { "id": "G3X7D0", "url": "https://omabrowser.org/oma/group/G3X7D0/", "database": "OMA" } ], "glygen_name": "Yeast", "common_name": "Baker's yeast" }, { "uniprot_canonical_ac": "Q54VL8-1", "protein_name": "WD40 repeat-containing protein", "gene_name": "", "tax_id": 44689, "organism": "Dictyostelium discoideum", "sequence": { "sequence": "MSSSTINITSDEINFLIYKYLLESGFQHAAFSFYNESLVSKSDINASNVPHGSLVSVLQKGLQYMEVEAHLQEDGTEINCTEPFSLVSNHVCQVKKKNEKNTTIKEKDDSISSSSSSSSSSSSSNNKNNSLNSGTNNNNSNNINTNSNSSNKDKKDKKESNTNTTTTSSSSWSSITHRINVVGVGSGSGGGGGSSSSSDKHDKEKDKYDRDVKMKEEDSIEIPDSQVTTLLGHSNEVFICAWNPSQSLLASGSGDSTARIWKIPPGPCENSKEQVSSLVLNHRNPNYNEKTIDVTTLEWSSDGSLLATGSYDGLGRIWNKNGNLIYILEQHQAPIFSLKWNKKGNYLLSGSVDKTSIVWDVKTGGVKQQFEFHTAPTLDIDWRNNTQFATCSTDKMIYVCEIGKEKPIMNFQGHHDEINAIKWDPTGTLLASCSDDYTAKIWSMKTGGCLFDFKDHTKEIYTIKWSPTGPDSNNPNKNLVLASASFDNTIKLWDVDVGKCIYSLKKHMDPVYTVSFSPNGEYLASGSFDKYLHIWSVKDGSLVKSYKGSGGIFEVCWNSSGDKISACYSNSTVCVLDFRS", "length": 580 }, "evidence": [ { "id": "G3X7D0", "url": "https://omabrowser.org/oma/group/G3X7D0/", "database": "OMA" } ], "glygen_name": "Cellular slime mold", "common_name": "Social amoeba" }, { "uniprot_canonical_ac": "Q95RJ9-1", "protein_name": "F-box-like/WD repeat-containing protein ebi", "gene_name": "ebi", "tax_id": 7227, "organism": "Drosophila melanogaster", "sequence": { "sequence": "MSFSSDEVNFLVYRYLQESGFLHSAYVFGIESHISQSNINGALVPPAALLTILQKGLLYTEVEWSVGEDGEVARPIEGLSLIDAVMPEVKPLKPIVKTEPGKPGAVDSSAPAGGNQNNNAKPEIKIEPGTGVAGSAGGNKIAGSTTGTSTPTDQSASEVDSSGNAANNAGGTYAGNNGAGGNQASTGGSNSTSTPAGGDLAAPGASQKKSQNSNEAGSSSSGNAGNANATSTDDAASSTSTNGNSSTSSSVEQPTSGLTPAGGTVSTSNPDAAASGGASTATGSKAPSGAVTIRVGAQGNNVQSGSSNAQSSAPSGTISSSTSGGAGTPAALVPMDIDENIEIPESKARVLRGHESEVFICAWNPSRDLLASGSGDSTARIWDMSDANTNSNQLVLRHCIQKGGAEVPSNKDVTSLDWNCDGSLLATGSYDGYARIWKTDGRLASTLGQHKGPIFALKWNKCGNYILSAGVDKTTIIWDASTGQCTQQFAFHSAPALDVDWQTNQAFASCSTDQRIHVCRLGVNEPIKTFKGHTNEVNAIKWCPQGQLLASCSDDMTLKIWSMNRDRCCHDLQAHSKEIYTIKWSPTGPGTNNPNTNLILASASFDSTVRLWDVERGSCIHTLTKHTEPVYSVAFSPDGKHLASGSFDKCVHIWSTQTGQLVHSYKGTGGIFEVCWNSKGTKVGASASDGSVFVLDLRKF", "length": 700 }, "evidence": [ { "id": "G3X7D0", "url": "https://omabrowser.org/oma/group/G3X7D0/", "database": "OMA" } ], "glygen_name": "Fruit fly", "common_name": "Fruit fly" }, { "uniprot_canonical_ac": "Q9FN19-1", "protein_name": "WD40 repeat-containing protein HOS15", "gene_name": "HOS15", "tax_id": 3702, "organism": "Arabidopsis thaliana", "sequence": { "sequence": "MSSLTSVELNFLVFRYLQESGFTHAAFTLGYEAGINKSNIDGNMVPPGALIKFVQKGLQYMEMEANLSNSEVDIDEDFSFFQPLDLISKDVKELQDMLREKKRKERDMEKERDRSKENDKGVEREHEGDRNRAKEKDRHEKQKEREREREKLEREKEREREKIEREKEREREKMEREIFEREKDRLKLEKEREIEREREREKIEREKSHEKQLGDADREMVIDQTDKEIAGDGSTGAEPMDIVMTPTSQTSHIPNSDVRILEGHTSEVCACAWSPSASLLASGSGDATARIWSIPEGSFKAVHTGRNINALILKHAKGKSNEKSKDVTTLDWNGEGTLLATGSCDGQARIWTLNGELISTLSKHKGPIFSLKWNKKGDYLLTGSVDRTAVVWDVKAEEWKQQFEFHSGPTLDVDWRNNVSFATSSTDSMIYLCKIGETRPAKTFTGHQGEVNCVKWDPTGSLLASCSDDSTAKIWNIKQSTFVHDLREHTKEIYTIRWSPTGPGTNNPNKQLTLASASFDSTVKLWDAELGKMLCSFNGHREPVYSLAFSPNGEYIASGSLDKSIHIWSIKEGKIVKTYTGNGGIFEVCWNKEGNKIAACFADNSVCVLDFRM", "length": 613 }, "evidence": [ { "id": "G3X7D0", "url": "https://omabrowser.org/oma/group/G3X7D0/", "database": "OMA" } ], "glygen_name": "Arabidopsis", "common_name": "Mouse-ear cress" }, { "uniprot_canonical_ac": "Q9QXE7-1", "protein_name": "F-box-like/WD repeat-containing protein TBL1X", "gene_name": "Tbl1x", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MSITSDEVNFLVYRYLQESGFSHSAFTFGIESHISQSNINGTLVPPAALISILQKGLQYVEAEISINEDGTVFDGRPIESLSLIDAVMPDVVQTRQQAFREKLAQQQANAAAAAAAAAATATSTAATTPAAAAQQNPPKNGEATVNGEENGAHAINNHSKPMEIDGDVEIPPSKATVLRGHESEVFICAWNPVSDLLASGSGDSTARIWNLNENSNGGSTQLVLRHCIREGGHDVPSNKDVTSLDWNSDGTLLATGSYDGFARIWTEDGNLASTLGQHKGPIFALKWNKKGNYILSAGVDKTTIIWDAHTGEAKQQFPFHSAPALDVDWQNNTTFASCSTDMCIHVCRLGCDRPVKTFQGHTNEVNAIKWDPSGMLLASCSDDMTLKIWSMKQDACVHDLQAHSKEIYTIKWSPTGPATSNPNSNIMLASASFDSTVRLWDVERGVCIHTLTKHQEPVYSVAFSPDGKYLASGSFDKCVHIWNTQSGSLVHSYRGTGGIFEVCWNARGDKVGASASDGSVCVLDLRK", "length": 527 }, "evidence": [ { "id": "G3X7D0", "url": "https://omabrowser.org/oma/group/G3X7D0/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" } ], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 4, "go_terms": [ { "name": "nucleus", "id": "GO:0005634", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005634", "evidence": [ { "database": "UniProtKB", "id": "G3X7D0", "url": "https://www.uniprot.org/uniprotkb/G3X7D0" } ], "pmid": "" }, { "name": "transcription repressor complex", "id": "GO:0017053", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0017053", "evidence": [ { "database": "UniProtKB", "id": "G3X7D0", "url": "https://www.uniprot.org/uniprotkb/G3X7D0" } ], "pmid": "" }, { "name": "histone deacetylase complex", "id": "GO:0000118", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000118", "evidence": [ { "database": "UniProtKB", "id": "G3X7D0", "url": "https://www.uniprot.org/uniprotkb/G3X7D0" } ], "pmid": "" }, { "name": "mitotic spindle", "id": "GO:0072686", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0072686", "evidence": [ { "database": "UniProtKB", "id": "G3X7D0", "url": "https://www.uniprot.org/uniprotkb/G3X7D0" } ], "pmid": "" } ] }, { "name": "Molecular Function", "total": 2, "go_terms": [ { "name": "transcription corepressor activity", "id": "GO:0003714", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003714", "evidence": [ { "database": "UniProtKB", "id": "G3X7D0", "url": "https://www.uniprot.org/uniprotkb/G3X7D0" } ], "pmid": "" }, { "name": "histone binding", "id": "GO:0042393", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0042393", "evidence": [ { "database": "UniProtKB", "id": "G3X7D0", "url": "https://www.uniprot.org/uniprotkb/G3X7D0" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 7, "go_terms": [ { "name": "negative regulation of transcription by RNA polymerase II", "id": "GO:0000122", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000122", "evidence": [ { "database": "UniProtKB", "id": "G3X7D0", "url": "https://www.uniprot.org/uniprotkb/G3X7D0" } ], "pmid": "" }, { "name": "regulation of transcription by RNA polymerase II", "id": "GO:0006357", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006357", "evidence": [ { "database": "UniProtKB", "id": "G3X7D0", "url": "https://www.uniprot.org/uniprotkb/G3X7D0" } ], "pmid": "" }, { "name": "proteolysis", "id": "GO:0006508", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006508", "evidence": [ { "database": "UniProtKB", "id": "G3X7D0", "url": "https://www.uniprot.org/uniprotkb/G3X7D0" } ], "pmid": "" }, { "name": "positive regulation of transcription by RNA polymerase II", "id": "GO:0045944", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0045944", "evidence": [ { "database": "UniProtKB", "id": "G3X7D0", "url": "https://www.uniprot.org/uniprotkb/G3X7D0" } ], "pmid": "" }, { "name": "positive regulation of DNA-templated transcription", "id": "GO:0045893", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0045893", "evidence": [ { "database": "UniProtKB", "id": "G3X7D0", "url": "https://www.uniprot.org/uniprotkb/G3X7D0" } ], "pmid": "" }, { "name": "sensory perception of sound", "id": "GO:0007605", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007605", "evidence": [ { "database": "UniProtKB", "id": "G3X7D0", "url": "https://www.uniprot.org/uniprotkb/G3X7D0" } ], "pmid": "" }, { "name": "positive regulation of canonical Wnt signaling pathway", "id": "GO:0090263", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0090263", "evidence": [ { "database": "UniProtKB", "id": "G3X7D0", "url": "https://www.uniprot.org/uniprotkb/G3X7D0" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 158, "end_pos": 160, "annotation": "n_glycosylation_sequon" }, { "start_pos": 332, "end_pos": 334, "annotation": "n_glycosylation_sequon" }, { "start_pos": 333, "end_pos": 335, "annotation": "n_glycosylation_sequon" }, { "start_pos": 40, "end_pos": 42, "annotation": "n_glycosylation_sequon" }, { "start_pos": 424, "end_pos": 426, "annotation": "n_glycosylation_sequon" }, { "start_pos": 598, "end_pos": 600, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" }, { "name": "homologset.oma", "label": "OMA Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 158, "end_pos": 160 }, { "start_pos": 332, "end_pos": 334 }, { "start_pos": 333, "end_pos": 335 }, { "start_pos": 40, "end_pos": 42 }, { "start_pos": 424, "end_pos": 426 }, { "start_pos": 598, "end_pos": 600 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ], "tool_support": { "graph_view": "yes" } }, { "uniprot_canonical_ac": "G3X748-1", "uniprot_ac": "G3X748", "uniprot_id": "G3X748_BOVIN", "mass": { "chemical_mass": 67909.0, "monoisotopic_mass": 67909.0 }, "refseq": { "ac": "XP_024844316", "name": "protein POF1B isoform X2", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_024844316" }, "gene_names": [ { "name": "POF1B", "type": "recommended", "evidence": [ { "id": "G3X748", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3X748" } ] }, { "name": "POF1B", "type": "synonym", "evidence": [ { "id": "XP_024844316", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_024844316" } ] } ], "protein_names": [ { "name": "POF1B actin binding protein", "type": "synonym", "evidence": [ { "id": "G3X748", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3X748/entry#names_and_taxonomy" } ] }, { "name": "protein POF1B isoform X2", "type": "synonym", "evidence": [ { "id": "XP_024844316", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_024844316" } ] } ], "function": [], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Bos taurus", "taxid": 9913, "evidence": [ { "database": "UniProtKB", "id": "G3X748", "url": "https://www.uniprot.org/uniprotkb/G3X748" } ], "common_name": "Bovine", "glygen_name": "Bovine", "reference_species": "Bos taurus [9913]" } ], "gene": [ { "name": "POF1B", "url": "https://www.uniprot.org/uniprotkb/G3X748", "locus": { "chromosome": "X", "start_pos": 66967820, "end_pos": 66868288, "strand": "-", "evidence": [ { "database": "Ensembl Gene", "id": "ENSBTAG00000014485", "url": "https://www.ensembl.org/id/ENSBTAG00000014485" } ] } } ], "crossref": [ { "id": "G3X748", "url": "https://alphafold.ebi.ac.uk/entry/G3X748", "database": "AlphaFoldDB", "categories": [] }, { "id": "ENSBTAG00000014485", "url": "https://bgee.org/?page=gene&gene_id=ENSBTAG00000014485", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "614768", "url": "https://www.ncbi.nlm.nih.gov/gene/614768", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR026186", "url": "https://www.ebi.ac.uk/interpro/entry/IPR026186", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR056240", "url": "https://www.ebi.ac.uk/interpro/entry/IPR056240", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "bta:614768", "url": "https://www.genome.jp/dbget-bin/www_bget?bta:614768", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "HHYYRRQ", "url": "https://omabrowser.org/oma/group/HHYYRRQ/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "G3X748", "url": "https://www.orthodb.org/?gene=G3X748", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR22546", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR22546", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR22546:SF0", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR22546:SF0", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF24617", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF24617", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "XP_024844316", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_024844316", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A3Q1M9P6", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1M9P6", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A3Q1M9P6-1", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1M9P6-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "G3X748", "url": "https://www.uniprot.org/uniprotkb/G3X748", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "G3X748-1", "url": "https://www.uniprot.org/uniprotkb/G3X748-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MMSSSYSSEMSSSSCGTQQSPEVLPCQPQHYHCYRQSSQAQQPPEKNIVYQRVRTYSGPMNKVVQTLDPVGSGEVLSPLKTASSYQSLVWSDHSQELHSPTLKISTCVPGTLHITPNTEQELHSPTVKVTTYPQTTIRRYIVQSPEQEPLSPFLRGGHFFPGNNVIYEKTIRKVEKLNMDQESYPQIQCNHHIVQQPQIIHSPHCEQSHSSQKIQTITGSDSVSTNTGIELCHGGSNHTHEQVIIQDDSPEKLDPKYFGELLADLSRKNTDLYHCLLEHLQRIGGSKRDFESIDESEDIESLIPKGLSEFTKQQIRYILQMRDMSAKSLRLVLSTFSNIREELGHLQNDLTSLENDKIRLEKDLAFKETQIKEYEELLASVRADNRQQQQGCQDSTSKCQALEEHNLSLRHTLSDVEYRLKELEYCKRNLEQENKNLRIQVSETCTGPMLQAKMDEIGNHYMEMVKNLRMEKDREICKLRTQLNQYQKDVSRREGSCNDFQFKIHELTSLLEEKDSLIKRQSEELSKLRQEIYSSHNQPSSGGRTTITTKKYRTQYPILGLLYDDYEYIPPGSDTKTIVIEKTEDKWTCP", "length": 590, "header": "tr|G3X748-1|G3X748_BOVIN Isoform 1 of POF1B actin binding protein OS=Bos taurus OX=9913 GN=POF1B PE=4 SV=2 CANONICAL=G3X748-1" }, "isoforms": [ { "isoform_ac": "A0A3Q1M9P6-1", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1M9P6/entry", "sequence": { "sequence": "MMSSSYSSEMSSSSCGTQQSPEVLPCQPQHYHCYRQSSQAQQPPEKNIVYQRVRTYSGPMNKVVQTLDPVGSGEVLSPLKTASSYQSLVWSDHSQELHSPTLKISTCVPGTLHITPNTEQCEDFFLTKELHSPTVKVTTYPQTTIRRYIVQSPEQEPLSPFLRGGHFFPGNNVIYEKTIRKVEKLNMDQESYPQIQCNHHIVQQPQIIHSPHCEQSHSSQKIQTITGSDSVSTNTGIELCHGGSNHTHEQVIIQDDSPEKLDPKYFGELLADLSRKNTDLYHCLLEHLQRIGGSKRDFESIDESEDIESLIPKGLSEFTKQQIRYILQMRDMSAKSLRLVLSTFSNIREELGHLQNDLTSLENDKIRLEKDLAFKETQIKEYEELLASVRADNRQQQQGCQDSTSKCQALEEHNLSLRHTLSDVEYRLKELEYCKRNLEQENKNLRIQVSETCTGPMLQAKMDEIGNHYMEMVKNLRMEKDREICKLRTQLNQYQKDVSRREGSCNDFQFKIHELTSLLEEKDSLIKRQSEELSKLRQEIYSSHNQPSSGGRTTITTKKYRTQYPILGLLYDDYEYIPPGSDTKTIVIEKTEDKWTCP", "length": 598, "header": "tr|A0A3Q1M9P6-1|A0A3Q1M9P6_BOVIN Computationally mapped isoform of POF1B actin binding protein OS=Bos taurus OX=9913 GN=POF1B PE=4 SV=2 CANONICAL=G3X748-1" }, "locus": { "chromosome": "X", "start_pos": 66966816, "end_pos": 66868539, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000068932.3", "url": "https://www.ensembl.org/id/ENSBTAT00000068932.3" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000066905.2", "url": "https://www.ensembl.org/id/ENSBTAP00000066905.2" } ] } }, { "isoform_ac": "G3X748-1", "url": "https://www.uniprot.org/uniprotkb/G3X748/entry", "sequence": { "sequence": "MMSSSYSSEMSSSSCGTQQSPEVLPCQPQHYHCYRQSSQAQQPPEKNIVYQRVRTYSGPMNKVVQTLDPVGSGEVLSPLKTASSYQSLVWSDHSQELHSPTLKISTCVPGTLHITPNTEQELHSPTVKVTTYPQTTIRRYIVQSPEQEPLSPFLRGGHFFPGNNVIYEKTIRKVEKLNMDQESYPQIQCNHHIVQQPQIIHSPHCEQSHSSQKIQTITGSDSVSTNTGIELCHGGSNHTHEQVIIQDDSPEKLDPKYFGELLADLSRKNTDLYHCLLEHLQRIGGSKRDFESIDESEDIESLIPKGLSEFTKQQIRYILQMRDMSAKSLRLVLSTFSNIREELGHLQNDLTSLENDKIRLEKDLAFKETQIKEYEELLASVRADNRQQQQGCQDSTSKCQALEEHNLSLRHTLSDVEYRLKELEYCKRNLEQENKNLRIQVSETCTGPMLQAKMDEIGNHYMEMVKNLRMEKDREICKLRTQLNQYQKDVSRREGSCNDFQFKIHELTSLLEEKDSLIKRQSEELSKLRQEIYSSHNQPSSGGRTTITTKKYRTQYPILGLLYDDYEYIPPGSDTKTIVIEKTEDKWTCP", "length": 590, "header": "tr|G3X748-1|G3X748_BOVIN Isoform 1 of POF1B actin binding protein OS=Bos taurus OX=9913 GN=POF1B PE=4 SV=2 CANONICAL=G3X748-1" }, "locus": { "chromosome": "X", "start_pos": 66966816, "end_pos": 66868539, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000019260.8", "url": "https://www.ensembl.org/id/ENSBTAT00000019260.8" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000019260.6", "url": "https://www.ensembl.org/id/ENSBTAP00000019260.6" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [ { "id": "bta:614768", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?bta:614768", "resource": "KEGG Pathway" } ], "orthologs": [ { "uniprot_canonical_ac": "A0A8V0Z5M6-1", "protein_name": "POF1B actin binding protein", "gene_name": "POF1B", "tax_id": 9031, "organism": "Gallus gallus", "sequence": { "sequence": "MLGGQQQLQPLALPPHLQQQQHHYYRRQQHYSTLPAPRRPCREPPPCPEPPPCPETPPCREPPACPEPPLPPPCFEPPAPQRQESGPAFDRVRTYGPGCRRVGSSCSSRAASPLECSHGHQQLSAGCQPPPQGTIRRIIIENPEQEPLSPFLRGGNFCPGNNVIYEKTIRKYELLNPHQEKQYQFSHQCQVPQPSDQCRAFQPCQQPEQPPVTHQCQQTQTSSPCEVLPVSVTDDCRGNTVRRVTVQTCEQENNDQLDCRYFGELLAELNRKTNDLYSCLLQHVEKIGGRNHDIEFTSQTEDIEELIPKGLSEATKQQIRYLLQMRVTSDKSLRLVLSTFKNLREELCHLQDDLGKLETDNVLLKKDLAFKETQVKEYETMLCSLRENNRQQQQGLRESTARCRSLEEQLLSLRLSEGEKDCQLKELECSKRALDQEIQSLKLQICSSPTVQTTTDELSSRYVEMINNLREDKDREIRSLRSQLCQFQQDISRQEGNNSDLQIKLHELTAMLEEKDVCIKQQQEELFRLKHERVSSSQSPGVTAVITKKYRNQYPILGLLSDDYKVTSPVNKSQTIVIERTGEIWKHE", "length": 588 }, "evidence": [ { "id": "G3X748", "url": "https://omabrowser.org/oma/group/G3X748/", "database": "OMA" } ], "glygen_name": "Chicken", "common_name": "Chicken" }, { "uniprot_canonical_ac": "D3ZWE3-1", "protein_name": "POF1B, actin binding protein", "gene_name": "Pof1b", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MMSSSYWSETSSSSCGTQQPTEVLQCQPQHYHCYHQSSQAQQPPEKNVVYERVRTYSGPMNKVVQALDPLGSREVLSPLKPASSYQNLVWSDHSQELHSPTLKISTCAPSTLHITQNAEQELHSPTVKVTTYPQTTIRRYIVQNPDQEPLSPFLRGGQFFPGNNVIYEKTIRKVEKLNTDQECCPQIQCHHHVIQQPQIIHSPHCQQSHSSHQIQCITENDSNVGHELCHGGPSQIHEQLIIQDDGPEKLDPKYFGELLADLSRKNTDLYHCLLEHLERIGGSKQDFETADTSEDIESLIPKGLSEFTKQQIRYILQMRGMSDKSLRLVLSTFSNIREELGHLQNDLTSLENDKIRLEKDLAFKENQIKEYEELLASVRANNRQQQQGLQDSSSKCQTLEENNLSLRHTLSDMEYRLKELEYCKRNLEQENKNLRIQVSETCTGSMLQGKMDEIGNHYMEMVKNLRLEKDREISKLRSQLNQYQKDVSKREGSCSDFQFKLHELTSLLEEKDSLIKRQSEELSKLRQEIYSSHNQPSGGGRTTITTKKYRTQYPILGLLYDDYEYIPPGSDTQTIVIEKTEDKWTCP", "length": 587 }, "evidence": [ { "id": "G3X748", "url": "https://omabrowser.org/oma/group/G3X748/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "F1S1P8-1", "protein_name": "POF1B actin binding protein", "gene_name": "POF1B", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MMSSSYWNERSSSCGTQQSPEGQQCQPQHYHWYHQSSQAQQPPEKNVVYERVRTYSGPMNKVVQSLDPISSREVFSPLKTASSYQNLVWSNHSQELHSPTLKISACAPSTLHLAPTTEQELHSPTVKVTSYPQTTIRRYIVQNPEQESLSPFLRGGHFFPGNNVIYEKTIRKVEKLNTDQECYPQVQCHHHFVQQPQIIYSPHCQQSHSSQQTQTITGSDLISTNTGNELCHGGANHTHEQVIMQDDGPEILDPKYFGELLADLSRKNTDLYHCLLEHLQRIGGSKQDFESTNESEDIELLIPKGLSEFTKQQIRYILQMRGMSDKSLRLVLSTFSNIREELGHLQNDLTSLENDKIRLEKDLAFKETQIKEYEELLASVRANNRQQHQGLQDSTSKCQALEENNLSLRHTLSDIEYRLKELEYCKRNLEEENKNLKMQVSETCTSPMLQAKMDEIGNHYMEMLKNLRMEKDREICKLRTQLNQYQKDVSRREGSCSDFQFKLHELTSLLEEKDSLIKRQSEELSKLRQEIYSSHNQPSSGGRTTITTRKYRTQYPILGLLYDDYEYIPPGSDTQTIVIEKTEDKWTCP", "length": 589 }, "evidence": [ { "id": "G3X748", "url": "https://omabrowser.org/oma/group/G3X748/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "Q8K4L4-1", "protein_name": "Protein POF1B", "gene_name": "Pof1b", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MMSSSYWSETSSSSCGTQQPTEVLQCQPQHYHYYHQPSQAQQPPEKNVVYERVRTYSGPMNKVVQALDPLGSREVLSPLKPASSYQSLVWSDHSQELYSPTLKISTCAPSTLHITQNAEQELHSPTVKVTTYPQTTIRRYIVQNPEQEPLSPFLRGSQFFPGNNVIYEKTIRKVEKLNTDQECCPQIQCHHHVIQQPQIIHSPHCQQSHSSHQIQCITENDSNIGHELCHGGPSQIHEQVIIQDDGPEKLDPKYFGELLADLSRKNTDLYHCLLEHLERIGGSKQDFESTDTSEDIESLIPKGLSEFTKQQIRYILQMRGMSDKSLRLVLSTFSNIREELGHLQNDLTSLENDKIRLEKDLAFKENQMKEYEELLASVRANNRQQQQGLQDSSAKCQSLEENNLSLRHTLSDLEYRLKELEYCKRNLEQENKNLRIQVSETCTGPTLQAKMDEIGNHYMEMVKNLRLDKDREISKLRSQLNQYQKDVSKREGSCSDFQFKLHELTSLLEEKDSLIKRQSEELSKLRQEIYSSHNQPSCGGRTTITTKKYRTQYPILGLLYDDYEYIPPGSDTQTIVIEKTEDKWTCP", "length": 587 }, "evidence": [ { "id": "G3X748", "url": "https://omabrowser.org/oma/group/G3X748/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q8WVV4-2", "protein_name": "Protein POF1B", "gene_name": "POF1B", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MSSSYWSETSSSSCGTQQLPEVLQCQPQHYHCYHQSSQAQQPPEKNVVYERVRTYSGPMNKVVQALDPFNSREVLSPLKTTSSYQNLVWSDHSQELHSPTLKISTCAPSTLHITQNTEQELHSPTVKLTTYPQTTIRKYVVQNPEQEPLSQFLRGSHFFPGNNVIYEKTIRKVEKLNTDQGCHPQAQCHHHIIQQPQVIHSAHWQQPDSSQQIQAITGNNPISTHIGNELCHSGSSQICEQVIIQDDGPEKLDPRYFGELLADLSRKNTDLYHCLLEHLQRIGGSKQDFESTDESEDIESLIPKGLSEFTKQQIRYILQMRGMSDKSLRLVLSTFSNIREELGHLQNDMTSLENDKMRLEKDLSFKDTQLKEYEELLASVRANNHQQQQGLQDSSSKCQALEENNLSLRHTLSDMEYRLKELEYCKRNLEQENQNLRMQVSETCTGPMLQAKMDEIGNHYTEMVKNLRMEKDREICRLRSQLNQYHKDVSKREGSCSDFQFKLHELTSLLEEKDSLIKRQSEELSKLRQEIYSSHNQPSTGGRTTITTKKYRTQYPILGLLYDDYEYIPPGSETQTIVIEKTEDKYTCP", "length": 589 }, "evidence": [ { "id": "G3X748", "url": "https://omabrowser.org/oma/group/G3X748/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" } ], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 5, "go_terms": [ { "name": "Golgi apparatus", "id": "GO:0005794", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005794", "evidence": [ { "database": "UniProtKB", "id": "G3X748", "url": "https://www.uniprot.org/uniprotkb/G3X748" } ], "pmid": "" }, { "name": "actin filament", "id": "GO:0005884", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005884", "evidence": [ { "database": "UniProtKB", "id": "G3X748", "url": "https://www.uniprot.org/uniprotkb/G3X748" } ], "pmid": "" }, { "name": "adherens junction", "id": "GO:0005912", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005912", "evidence": [ { "database": "UniProtKB", "id": "G3X748", "url": "https://www.uniprot.org/uniprotkb/G3X748" } ], "pmid": "" }, { "name": "bicellular tight junction", "id": "GO:0005923", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005923", "evidence": [ { "database": "UniProtKB", "id": "G3X748", "url": "https://www.uniprot.org/uniprotkb/G3X748" } ], "pmid": "" }, { "name": "desmosome", "id": "GO:0030057", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030057", "evidence": [ { "database": "UniProtKB", "id": "G3X748", "url": "https://www.uniprot.org/uniprotkb/G3X748" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 3, "go_terms": [ { "name": "actin filament organization", "id": "GO:0007015", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007015", "evidence": [ { "database": "UniProtKB", "id": "G3X748", "url": "https://www.uniprot.org/uniprotkb/G3X748" } ], "pmid": "" }, { "name": "bicellular tight junction assembly", "id": "GO:0070830", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0070830", "evidence": [ { "database": "UniProtKB", "id": "G3X748", "url": "https://www.uniprot.org/uniprotkb/G3X748" } ], "pmid": "" }, { "name": "epithelial cell morphogenesis", "id": "GO:0003382", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003382", "evidence": [ { "database": "UniProtKB", "id": "G3X748", "url": "https://www.uniprot.org/uniprotkb/G3X748" } ], "pmid": "" } ] }, { "name": "Molecular Function", "total": 1, "go_terms": [ { "name": "actin filament binding", "id": "GO:0051015", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0051015", "evidence": [ { "database": "UniProtKB", "id": "G3X748", "url": "https://www.uniprot.org/uniprotkb/G3X748" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 237, "end_pos": 239, "annotation": "n_glycosylation_sequon" }, { "start_pos": 406, "end_pos": 408, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "G3X748", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3X748" }, { "id": "PF24617", "database": "Pfam", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF24617" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "POF1B helix-loop-helix", "eco_id": "ECO_0000259", "start_pos": 256, "end_pos": 336, "start_aa": "Lys", "end_aa": "Phe", "glycosite_overlap": [] } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" }, { "name": "homologset.oma", "label": "OMA Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 237, "end_pos": 239 }, { "start_pos": 406, "end_pos": 408 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ 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"count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ], "tool_support": { "graph_view": "yes" } }, { "uniprot_canonical_ac": "G3X6A0-1", "uniprot_ac": "G3X6A0", "uniprot_id": "G3X6A0_BOVIN", "mass": { "chemical_mass": 50336.0, "monoisotopic_mass": 50336.0 }, "refseq": { "ac": "XP_010814925", "name": "monocarboxylate transporter 6 isoform X1", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_010814925" }, "gene_names": [ { "name": "SLC16A5", "type": "recommended", "evidence": [ { "id": "G3X6A0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3X6A0" } ] }, { "name": "SLC16A5", "type": "synonym", "evidence": [ { "id": "XP_010814925", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_010814925" } ] } ], "protein_names": [ { "name": "Solute carrier family 16 member 5", "type": "synonym", "evidence": [ { "id": "G3X6A0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3X6A0/entry#names_and_taxonomy" } ] }, { "name": "monocarboxylate transporter 6 isoform X1", "type": "synonym", "evidence": [ { "id": "XP_010814925", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_010814925" } ] } ], "function": [], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Bos taurus", "taxid": 9913, "evidence": [ { "database": "UniProtKB", "id": "G3X6A0", "url": "https://www.uniprot.org/uniprotkb/G3X6A0" } ], "common_name": "Bovine", "glygen_name": "Bovine", "reference_species": "Bos taurus [9913]" } ], "gene": [ { "name": "SLC16A5", "url": "https://www.uniprot.org/uniprotkb/G3X6A0", "locus": { "chromosome": "19", "start_pos": 56338625, "end_pos": 56354027, "strand": "+", "evidence": [ { "database": "Ensembl Gene", "id": "ENSBTAG00000001110", "url": "https://www.ensembl.org/id/ENSBTAG00000001110" } ] } } ], "crossref": [ { "id": "G3X6A0", "url": "https://alphafold.ebi.ac.uk/entry/G3X6A0", "database": "AlphaFoldDB", "categories": [] }, { "id": "ENSBTAG00000001110", "url": "https://bgee.org/?page=gene&gene_id=ENSBTAG00000001110", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "531531", "url": "https://www.ncbi.nlm.nih.gov/gene/531531", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR004743", "url": "https://www.ebi.ac.uk/interpro/entry/IPR004743", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR011701", "url": "https://www.ebi.ac.uk/interpro/entry/IPR011701", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR020846", "url": "https://www.ebi.ac.uk/interpro/entry/IPR020846", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR036259", "url": "https://www.ebi.ac.uk/interpro/entry/IPR036259", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR050327", "url": "https://www.ebi.ac.uk/interpro/entry/IPR050327", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "bta:531531", "url": "https://www.genome.jp/dbget-bin/www_bget?bta:531531", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "TWGAYQT", "url": "https://omabrowser.org/oma/group/TWGAYQT/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "G3X6A0", "url": "https://www.orthodb.org/?gene=G3X6A0", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR11360", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR11360", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR11360:SF21", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR11360:SF21", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF07690", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF07690", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "XP_010814925", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_010814925", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0AAA9TWK9", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TWK9", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0AAA9TWK9-1", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TWK9-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "G3X6A0", "url": "https://www.uniprot.org/uniprotkb/G3X6A0", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "G3X6A0-1", "url": "https://www.uniprot.org/uniprotkb/G3X6A0-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MSQALERSEGCWAWVVLLASVVTQGLTLGFPTCIGIFFTELQREFQASNSETSWFPSILTAMLHAGGPLCSILVGRFGCRATMMLGGVLASLGMVAGSFCRTLGQLYLTAGFITGLGMCFSFQSSITVLGLYFTRWQVLANALASAGVSLGITLWPLLSRYLLEDLGWRGTFLIFGGVLLHCCVCGAVVRPVPASVTPEAREGLPSPSKRPSRGCPAACGRAIRRHLAFDVLRDNVGYRVYTLGVVWMILGFPLPHVFLVPYAIRHGMDEQKAALLISVIGFSNIFLRPMAGLVAGRREFAGHRKYLFSLAALLNGLTNLVCVASADFRVLVGYCLAYSVSMSGIGALLFQVLMDIVPMDRFSSALGLFTVLESISILISPPLAGLLLDTTDDFSYVFYMSSFFLISAALFMGGSFCVLGKKERQGPWAEAKGAVPEAAPEQGLATEDMDGPEKRLRVEIMYVTSV", "length": 466, "header": "tr|G3X6A0-1|G3X6A0_BOVIN Isoform 1 of Solute carrier family 16 member 5 OS=Bos taurus OX=9913 GN=SLC16A5 PE=3 SV=2 CANONICAL=G3X6A0-1" }, "isoforms": [ { "isoform_ac": "A0AAA9TWK9-1", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TWK9/entry", "sequence": { "sequence": "MSQALERSEGCWAWVVLLASVVTQGLTLGFPTCIGIFFTELQREFQASNSETSWFPSILTAMLHAGGPLCSILVGRFGCRATMMLGGVLASLGMVAGSFCRTLGQLYLTAGFITGLGMCFSFQSSITVLGLYFTRWQVLANALASAGVSLGITLWPLLSRYLLEDLGWRGTFLIFGGVLLHCCVCGAVVRPVPASVTPEAREGLPSPSKRPSRGCPAACGRAIRRHLAFDVLRDNVGYRVYTLGVVWMILGFPLPHVFLVPYAIRHGMDEQKAALLISVIGFSNIFLRPMAGLVAGRREFAGHRKYLFSLAALLNGLTNLVCVASADFRVLVGYCLAYSVSMSGIGALLFQVLMDIVPMDRFSSALGLFTVLESISILISPPLAGLSLWWKSRGLGQRGTFAIMVVILCWKGSKQIWKQRPTGVAVLEAETPPGHHRRLQLRFLHVKFLPHLGCPLHGWQFLCPGQEGAAGPVG", "length": 474, "header": "tr|A0AAA9TWK9-1|A0AAA9TWK9_BOVIN Computationally mapped isoform of Solute carrier family 16 member 5 OS=Bos taurus OX=9913 GN=SLC16A5 PE=4 SV=1 CANONICAL=G3X6A0-1" }, "locus": { "chromosome": "19", "start_pos": 56348553, "end_pos": 56339741, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000120990.1", "url": "https://www.ensembl.org/id/ENSBTAT00000120990.1" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000103037.1", "url": "https://www.ensembl.org/id/ENSBTAP00000103037.1" } ] } }, { "isoform_ac": "G3X6A0-1", "url": "https://www.uniprot.org/uniprotkb/G3X6A0/entry", "sequence": { "sequence": "MSQALERSEGCWAWVVLLASVVTQGLTLGFPTCIGIFFTELQREFQASNSETSWFPSILTAMLHAGGPLCSILVGRFGCRATMMLGGVLASLGMVAGSFCRTLGQLYLTAGFITGLGMCFSFQSSITVLGLYFTRWQVLANALASAGVSLGITLWPLLSRYLLEDLGWRGTFLIFGGVLLHCCVCGAVVRPVPASVTPEAREGLPSPSKRPSRGCPAACGRAIRRHLAFDVLRDNVGYRVYTLGVVWMILGFPLPHVFLVPYAIRHGMDEQKAALLISVIGFSNIFLRPMAGLVAGRREFAGHRKYLFSLAALLNGLTNLVCVASADFRVLVGYCLAYSVSMSGIGALLFQVLMDIVPMDRFSSALGLFTVLESISILISPPLAGLLLDTTDDFSYVFYMSSFFLISAALFMGGSFCVLGKKERQGPWAEAKGAVPEAAPEQGLATEDMDGPEKRLRVEIMYVTSV", "length": 466, "header": "tr|G3X6A0-1|G3X6A0_BOVIN Isoform 1 of Solute carrier family 16 member 5 OS=Bos taurus OX=9913 GN=SLC16A5 PE=3 SV=2 CANONICAL=G3X6A0-1" }, "locus": { "chromosome": "19", "start_pos": 56348553, "end_pos": 56339629, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000001467.7", "url": "https://www.ensembl.org/id/ENSBTAT00000001467.7" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000001467.6", "url": "https://www.ensembl.org/id/ENSBTAP00000001467.6" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [ { "id": "bta:531531", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?bta:531531", "resource": "KEGG Pathway" } ], "orthologs": [ { "uniprot_canonical_ac": "A0A8V1ANC3-1", "protein_name": "Solute carrier family 16 member 5", "gene_name": "SLC16A5", "tax_id": 9031, "organism": "Gallus gallus", "sequence": { "sequence": "MAQGGAAARGAAKVQDQGWAWMVLVAAVVLQGLTLGFPSCIGVFFTDLQHEFQATNSETSWFPSIMVAVLHAGGPLCSILVKRFGCRFAVMVGGLLSSVGMVSSSFCKSLSQLYLTAGLVTGLGSCFSFQAGVTALGYYFVRWRTLANAMASTGVSIGLTLWPLLSQYLLDEMGWRNTFLIFGGILLNCCVCGAVMRPVKFALGSLLQFPSPEEEPGRRAEEVQLSNGASSPHLKLQEQTRKIACFQALQKYLAFDIFCQNKGYQIYTIGVTWMMMGFVLPHVYLVPYAIQNGVDERRAALLISIIGFINIFIRPLTGLLSGQTIFTGRRIYLYSLAVLLCGLSNFICVISAKFSMLIFYCVILSIAMSGIGALTFQVLMDVVEMDRFSSALGLFTILESITLLIGPPLTGLLVDITSDFRYVFYTSSFFLISASLFMVLSFCALEKKNKLKDTSKVPPDRSTIYNETPNESQSESQPTLAVVHITSI", "length": 488 }, "evidence": [ { "id": "G3X6A0", "url": "https://omabrowser.org/oma/group/G3X6A0/", "database": "OMA" } ], "glygen_name": "Chicken", "common_name": "Chicken" }, { "uniprot_canonical_ac": "D4A3B5-1", "protein_name": "Monocarboxylate transporter 6", "gene_name": "Slc16a5", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MPQALEQADGRWAWVVLLASLVTQALTVGFPSCIGVFFTDLQRDFQASNSETSWFPSIMGAMLHCGGPLCSILIKRFGCRVTMMLGGVLASLGMVASTFSDSLIHLFLTAGLITGLGMCFSFQSSITVVGLYFVRQRPLANALASIGISMGVTLWPLLARYLLETLGWRGAFLIFGGIFLHCCVCGAMLRPVATNVDPEPKEDLLLPPKTPTRSCLATCVSTIQYYLAFDILRHNMVFCIYVTGATWMTLGFSLPHIFLVPYAMHHGMEEYWAAMLMSIVGFCNIFLRPVAGMLAGRKSLAAYRKYLFAVAILINGLTNLICTVSADFRVLLGYCLVYSLSMCGTGILVFQVLMDIVPMDRFPSALGLFTILCGMGSLISPPLAGLLLDTTNNFNYVFYMSSGLLISASLFMGVGFYVAEKKLKQDRQAKMEDATSEITSKHSLTSEDKDSAKKQPYPENIYVTSV", "length": 466 }, "evidence": [ { "id": "G3X6A0", "url": "https://omabrowser.org/oma/group/G3X6A0/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "E7FB53-1", "protein_name": "Monocarboxylate transporter 6", "gene_name": "slc16a5a", "tax_id": 7955, "organism": "Danio rerio", "sequence": { "sequence": "MAPQQPSSMEEQSGELCEPESEELEKQGPGPPSNANAPDSYDAPDGGWGWVVLLATIIVLALTLAFPSCIIIFYLDLQKEFEATNSQTSWVPSIMTAVLHAGGPLCSVLVDRFGCRATVMFGGVLSGFGMAVSSFSHSIVDLYITAGVITGLGFCFSFQPAVTILGHYFVRRRPFANAMSSTGTALGLSTLPFLCDFLKIELGWRGSFLVLGAVLLNCCVCGAVMRPIRPRKPRKTNEINNSPKTSDKKGCMLGICQSLASSLRQQMAFDLFCSNTRFRVFSLGITWMMLGFVVPLIYLVPYASADDMDPSRAALLLSILGFVNIFVRPPVGVLFSLPWFKGRHIYVFSAALLINGLSNSICCISASFPVLLVYVLTYGLSMSVVGSLMFTVLMDTVEMSRFPSALGLLSIMESVTLLIGPPLAGFLVDRTQLYTYVFMACTIIVVLSALFLMFTFYWLDSRDAAKKDSPAKPAINISTDCQYSSVPIDGDKTNKPSSETENTTCV", "length": 506 }, "evidence": [ { "id": "G3X6A0", "url": "https://omabrowser.org/oma/group/G3X6A0/", "database": "OMA" } ], "glygen_name": "Zebrafish", "common_name": "Zebrafish" }, { "uniprot_canonical_ac": "O15375-1", "protein_name": "Monocarboxylate transporter 6", "gene_name": "SLC16A5", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MPQALERADGSWAWVVLLATMVTQGLTLGFPTCIGIFFTELQWEFQASNSETSWFPSILTAVLHMAGPLCSILVGRFGCRVTVMLGGVLASLGMVASSFSHNLSQLYFTAGFITGLGMCFSFQSSITVLGFYFVRRRVLANALASMGVSLGITLWPLLSRYLLENLGWRGTFLVFGGIFLHCCICGAIIRPVATSVAPETKECPPPPPETPALGCLAACGRTIQRHLAFDILRHNTGYCVYILGVMWSVLGFPLPQVFLVPYAMWHSVDEQQAALLISIIGFSNIFLRPLAGLMAGRPAFASHRKYLFSLALLLNGLTNLVCAASGDFWVLVGYCLAYSVSMSGIGALIFQVLMDIVPMDQFPRALGLFTVLDGLAFLISPPLAGLLLDATNNFSYVFYMSSFFLISAALFMGGSFYALQKKEQGKQAVAADALERDLFLEAKDGPGKQRSPEIMCQSSRQPRPAGVNKHLWGCPASSRTSHEWLLWPKAVLQAKQTALGWNSPT", "length": 505 }, "evidence": [ { "id": "G3X6A0", "url": "https://omabrowser.org/oma/group/G3X6A0/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" } ], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 3, "go_terms": [ { "name": "membrane", "id": "GO:0016020", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016020", "evidence": [ { "database": "UniProtKB", "id": "G3X6A0", "url": "https://www.uniprot.org/uniprotkb/G3X6A0" } ], "pmid": "" }, { "name": "plasma membrane", "id": "GO:0005886", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005886", "evidence": [ { "database": "UniProtKB", "id": "G3X6A0", "url": "https://www.uniprot.org/uniprotkb/G3X6A0" } ], "pmid": "" }, { "name": "basolateral plasma membrane", "id": "GO:0016323", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016323", "evidence": [ { "database": "UniProtKB", "id": "G3X6A0", "url": "https://www.uniprot.org/uniprotkb/G3X6A0" } ], "pmid": "" } ] }, { "name": "Molecular Function", "total": 3, "go_terms": [ { "name": "transmembrane transporter activity", "id": "GO:0022857", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0022857", "evidence": [ { "database": "UniProtKB", "id": "G3X6A0", "url": "https://www.uniprot.org/uniprotkb/G3X6A0" } ], "pmid": "" }, { "name": "symporter activity", "id": "GO:0015293", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0015293", "evidence": [ { "database": "UniProtKB", "id": "G3X6A0", "url": "https://www.uniprot.org/uniprotkb/G3X6A0" } ], "pmid": "" }, { "name": "monocarboxylic acid transmembrane transporter activity", "id": "GO:0008028", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008028", "evidence": [ { "database": "UniProtKB", "id": "G3X6A0", "url": "https://www.uniprot.org/uniprotkb/G3X6A0" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "G3X6A0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3X6A0" }, { "id": "PS50850", "database": "PROSITE", "url": "https://prosite.expasy.org/PS50850" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "Major facilitator superfamily (MFS) profile", "eco_id": "ECO_0000259", "start_pos": 13, "end_pos": 425, "start_aa": "Ala", "end_aa": "Gln", "glycosite_overlap": [] } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" }, { "name": "homologset.oma", "label": "OMA Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ], "tool_support": { "graph_view": "yes" } }, { "uniprot_canonical_ac": "G3N3U5-1", "uniprot_ac": "G3N3U5", "uniprot_id": "G3N3U5_BOVIN", "mass": { "chemical_mass": 144602.0, "monoisotopic_mass": 144602.0 }, "refseq": {}, "gene_names": [ { "name": "TBC1D32", "type": "recommended", "evidence": [ { "id": "G3N3U5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3N3U5" } ] } ], "protein_names": [ { "name": "Protein broad-minded", "type": "recommended", "evidence": [ { "id": "G3N3U5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3N3U5/entry#names_and_taxonomy" } ] }, { "name": "TBC1 domain family member 32", "type": "synonym", "evidence": [ { "id": "G3N3U5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3N3U5/entry#names_and_taxonomy" } ] } ], "function": [ { "annotation": "Required for high-level Shh responses in the developing neural tube. Together with CDK20, controls the structure of the primary cilium by coordinating assembly of the ciliary membrane and axoneme, allowing GLI2 to be properly activated in response to Shh signaling.", "evidence": [ { "database": "UniProtKB", "id": "F1N7V1", "url": "https://www.uniprot.org/uniprotkb/F1N7V1#function" }, { "database": "UniProtKB", "id": "ARBA00054310", "url": "https://www.uniprot.org/uniprotkb/ARBA00054310#function" }, { "database": "UniProtKB", "id": "G3N3U5", "url": "https://www.uniprot.org/uniprotkb/G3N3U5#function" }, { "database": "UniProtKB", "id": "A0ABI0P4I0", "url": "https://www.uniprot.org/uniprotkb/A0ABI0P4I0#function" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Bos taurus", "taxid": 9913, "evidence": [ { "database": "UniProtKB", "id": "G3N3U5", "url": "https://www.uniprot.org/uniprotkb/G3N3U5" } ], "common_name": "Bovine", "glygen_name": "Bovine", "reference_species": "Bos taurus [9913]" } ], "gene": [ { "name": "TBC1D32", "url": "https://www.uniprot.org/uniprotkb/G3N3U5", "locus": { "chromosome": "9", "start_pos": 30021574, "end_pos": 29816000, "strand": "-", "evidence": [ { "database": "Ensembl Gene", "id": "ENSBTAG00000009575", "url": "https://www.ensembl.org/id/ENSBTAG00000009575" } ] } } ], "crossref": [ { "id": "G3N3U5", "url": "https://alphafold.ebi.ac.uk/entry/G3N3U5", "database": "AlphaFoldDB", "categories": [] }, { "id": "ENSBTAG00000009575", "url": "https://bgee.org/?page=gene&gene_id=ENSBTAG00000009575", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "518886", "url": "https://www.ncbi.nlm.nih.gov/gene/518886", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR032735", "url": "https://www.ebi.ac.uk/interpro/entry/IPR032735", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR035969", "url": "https://www.ebi.ac.uk/interpro/entry/IPR035969", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR039156", "url": "https://www.ebi.ac.uk/interpro/entry/IPR039156", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR055391", "url": "https://www.ebi.ac.uk/interpro/entry/IPR055391", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR055392", "url": "https://www.ebi.ac.uk/interpro/entry/IPR055392", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "PTHR13465", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR13465", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR13465:SF3", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR13465:SF3", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF14961", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF14961", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF23431", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF23431", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF23440", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF23440", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "A0ABI0P4I0", "url": "https://www.uniprot.org/uniprotkb/A0ABI0P4I0", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0ABI0P4I0-1", "url": "https://www.uniprot.org/uniprotkb/A0ABI0P4I0-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "F1N7V1", "url": "https://www.uniprot.org/uniprotkb/F1N7V1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "F1N7V1-1", "url": "https://www.uniprot.org/uniprotkb/F1N7V1-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "G3N3U5", "url": "https://www.uniprot.org/uniprotkb/G3N3U5", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "G3N3U5-1", "url": "https://www.uniprot.org/uniprotkb/G3N3U5-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MAHFSGEDEAMLQAMLRQLFQSVKEKITGAPSLECAEEILLHLEETDENFHNYEFVKYLRQYICNTLGSMIEEEMEKWTSEQNQGEEFGYDTVVQHVTKRTQESKEYKEMIHSLKNIMKIVVESMINKFEEDEIRSQERQKKIQKEKSSSYCTDNCSDSDSSFNQSYKFCQGKLQLILDQLDPGQPKEVRYEALQTLCSAPPSDVLNCENWTTLCEKLTVYLSDPDPVFSDRILKFYAQTFTLSPLHMTKEIYTSLAKYLELYFLSRENNIPTLSTGIDISNPNVTHLLKKIRLLNEYQKEAPSFWIRHPEKYMEEIVESTLSLLSVKHDQSHLVSQKILDPIYFLALVDTKAVWFKKWMHAYYSRTAVLRLLEKKYKSLITTAVQQCVQYFELCETMKGDEVLGHSKSCGIKQKTFYYSGQELQYIYFIHSLSLLGRLLIYTQGRKLFPVKLKTRKDSVSLTDLLVLFTQLIYHSPTCPKMTSPGHLEDYSPASMATEVLCILCDQKECAIECLYNNTVIEALLQPIRNLMKGTKAAPNCSETALIHIAHILARIASVEEGLTLLLYGENMNSSEEKSPTGAHLIAQFSKKLLDEDISIFSGSEMFPVVKGAFSSVCRQIYGTCEGLQVLIPYSLHESIAKAWKKTSLLSERIPTPVEGSDSVSLVSQESQNIMAWEENLLDDLLNFAATPKGLLLLQRTGAINECVTFMFNQYAKKLQISRHKKFGYGVLVTQVASTAAGAIALRNSGFINALITELWANLECGRDDVRVTHPRSTPVDPIDQSCQKSFLALVNLLSYPAVFELVGNQSLPNKAEYSLREVPTSVIDIIDRLIILNSEAKIRSLFNYEQSHIFGLREFIIDSLSVERNHVLVRINLIGGPMERILPPRLLEKGDEPYPWPMFSSYPLPNCYLSDSVTRSTDLKQDNDLGKLLLRFKMSDKQTAWIENCRRQFCKIMKAKPDIISGGALVELLEKFVLHLSESPSECYFPSVEYTATDANVKNENLSSVQQLGIKMTVRYGKFLNLLKDGAENDLTLVLKHCERFLKQQQASIKSSLLCLQRNYTSHDWFVSSLFIIMLGDKDKTFQFLQQFSRLLTSAFLWLPRLHISRYLPIDTIESGIHPVYFCSTHYIEMLLKAEVPLVFSAFHMSGFAPSQICMQWITQCFWNYLDWIEICHYIATCVFLGPDYQVYICIAIFKHLQQDILQHTQTQDLQVFLKEEALHGFRVSDYFEYMEVLEQNYRPVLLRDMRNMRVQST", "length": 1259, "header": "tr|G3N3U5-1|G3N3U5_BOVIN Isoform 1 of Protein broad-minded OS=Bos taurus OX=9913 GN=TBC1D32 PE=4 SV=3 CANONICAL=G3N3U5-1" }, "isoforms": [ { "isoform_ac": "A0ABI0P4I0-1", "url": "https://www.uniprot.org/uniprotkb/A0ABI0P4I0/entry", "sequence": { "sequence": "MLQAMLRQLFQSVKEKITGAPSLECAEEILLHLEETDENFHNYEFVKYLRQYICNTLGSMIEEEMEKWTSEQNQGEEFGYDTVVQHVTKRTQESKEYKEMIHSLKNIMKIVVESMINKFEEDEIRSQERQKKIQKEKSSSYCTDNCSDSDSSFNQSYKFCQGKLQLILDQLDPGQPKEVRYEALQTLCSAPPSDVLNCENWTTLCEKLTVYLSDPDPVFSDRILKFYAQTFTLSPLHMTKEIYTSLAKYLELYFLSRENNIPTLSTGIDISNPNVTHLLKKIRLLNEYQKEAPSFWIRHPEKYMEEIVESTLSLLSVKHDQSHLVSQKILDPIYFLALVDTKAVWFKKWMHAYYSRTAVLRLLEKKYKSLITTAVQQCVQYFELCETMKGDEVLGHSKSCGIKQKTFYYSGQELQYIYFIHSLSLLGRLLIYTQGRKLFPVKLKTRKDSVSLTDLLVLFTQLIYHSPTCPKMTSPGHLEDYSPASMATEVLCILCDQKECAIECLYNNTVIEALLQPIRNLMKGTKAAPNCSETALIHIAHILARIASVEEGLTLLLYGENMNSSEEKSPTGAHLIAQFSKKLLDEDISIFSGSEMFPVVKGAFSSVCRQIYGTCEGLQVLIPYSLHESIAKAWKKTSLLSERIPTPVEGSDSVSLVSQESQNIKHGLYDMYTSSMAWEENLLDDLLNFAATPKGLLLLQRTGAINECVTFMFNQYAKKLQISRHKKFGYGVLVTQVASTAAGAIALRNSGFINALITELWANLECGRDDVRVTHPRSTPVDPIDQSCQKSFLALVNLLSYPAVFELVGNQSLPNKAEYSLREVPTSVIDIIDRLIILNSEAKIRSLFNYEQSHIFGLRLLSVVCCDLDTLLLLEAQYQVSELLLNAQEENTLETSESHREFIIDSLSVERNHVLVRINLIGGPMERILPPRLLEKGDEPYPWPMFSSYPLPNCYLSDSVTRSTDLKQDNDLGKLLLRFKMSDKQTAWIENCRRQFCKIMKAKPDIISGGALVELLEKFVLHLSESPSECYFPSVEYTATDANVKNENLSSVQQLGIKMTVRYGKFLNLLKDGAENDLTLVLKHCERFLKQQQASIKSSLLCLQRNYTSHDWFVSSLFIIMLGDKDKTFQFLQQFSRLLTSAFLWLPRLHISRYLPIDTIESGIHPVYFCSTHYIEMLLKAEVPLVFSAFHMSGFAPSQICMQWITQCFWNYLDWIEICHYIATCVFLGPDYQVYICIAIFKHLQQDILQHTQTQDLQVFLKEEALHGFRVSDYFEYMEVLEQNYRPVLLRDMRNMRVQST", 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"categories": [ "Protein" ] }, { "id": "A0AAA9TF22-1", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TF22-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "G5E5Q8", "url": "https://www.uniprot.org/uniprotkb/G5E5Q8", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "G5E5Q8-1", "url": "https://www.uniprot.org/uniprotkb/G5E5Q8-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MARLADYFVLVAFGPHPRGSGEGQGQILQRFPEKDWEDNPFPQGIELFCQPSGWQLCPERNPPTFFVAVLTDINSERHYCACLTFWEPVEPTQEELCARDAAERDEEANEGGPGALPPPTPSPPGQLFAPKTLVLVSRLDHVEVFRNSLGLIYTIHVEGLNVGLENVVGNLLTCVIPLAGGSQRTISLGAGDRQVIQTPLTDSLPISRCSVALLFRQLGITNVLSLFCAALTEHKVLFLSRSYQRLSDACRGLLALLFPLRYSFTYVPILPAQLLEVLSTPTPFIIGVNAAFQAEAQELLDVIVADLDGGTVTVPECVHIPPLPEPLQSQTHSILSMVLDPELELADLAFPPPTTSISSLKMQDKELRAVFLRLFAQLLQGYRWCLHMVRIHPEPVIRFHKAAFLGQRGLVEDDFLMKVLEGMAFAGFVSERGVPYRPTDLFDELVAHEVARMRADENHPQRVLRHVKELAEQLYKNENPYPAVAMHKVQRPGEASHLRRAPRPFPRLDEGMVQWIVDQATAKMQGAPPAVKAEKRTTVPSGPPMTAIVERSGGLHGNSARRLEVVRNCISYVFEGKMLEAKKLLPAVLRALKGRAARRCLAQELHLHVQQNRAVLDHQQFDFVVRMMNCCLQDCTSLDEHGIAAALLPLVTAFCRKLSPGVTQFAYSCVQEHVVWSTPQFWEAMFYGDVQTHIRALYLEPAEDRDSFSVGEAPVQEDERSALDVASEQRRLWPTLSREKQQELVQKEESTVFSQAIHYANRMSYLLLPLDSSKSRLLRERAGLGELESASNSLVTNSMAGSVAESYDTESGFEDAETCDVAGAVVRFINRFVDKVCTESGVTSDHLKGLHVMVPDIVQMHIETLEAVHRESKRLPPIQKPKLLRPRLLPGEECVLDGLRVYLLPDGREEGAGGPGGGPALLPAEGAVFLTTYRVIFTGMPTDPLVGEQVVVRSFPVAALTKEKRVSVQTPVDQLLQDGLQLRSCTFQLLKMAFDEEVGSDSAELFRKQLHKLRYPPDIRGTFALSLGSAHTPGRPPRANKDKGPSFRTLSRNLVKNAKKTIGRQYVTRKKYNPPSWEHRGQPPPEDQEDEISVSEELEPSTLTPSSALKPSDRMTMSSLVERACCRDYQRLGLGTLSSSLSRAKSEPFRISPVNRMYAICRSYPGLLIVPQSVQDNALQRVSRCYRQNRFPVVCWRSGRSKAVLLRSGGLHGKGVVGLFKAQNAPSPGQSQADSSSLEQEKYLQAVVSSMPRYADASGRNTLSGFSSAHMGSHGKWGSVRASGRSGGLSTDVGSRLAGVGPPQANGAPPEPGFLRPQRAALYIIGDKAQLKGVRPDPLQQWELVPIEVFEARQVKASFKKLLKACVPGCPATEPSPASFLRSLEDSEWLIQIHKLLQVSVLVVELLDSGSSVLVSLEDGWDITTQVVSLVQLLSDPFYRTLEGFRLLVEKEWLSFGHRFSHRGAHTLAGQSSGFTPVFLQFLDCVHQIHLQFPMEFEFSPFYLKFLGYHHVSRRFRTFLLDSDYERIELGLLYEEKGDRRAPQACRSVWEYVERLSKRTPVFYNYMYAPEDAEVLRPYSNVSNLKVWDFYTEETLAEGPPYDWELAQGPPEPPEEERPDGGAPQSRRRVVWPCYDSRPRAQPDAISRLLEEMQRLETELGRPPERWKDAWDRVKAAQRLEGRPDGRGTPSSLLVSSVPHHRRSLGVYLQEGPVGSTLSLSLDSDQSSGSTASSSRQAARRSTSTLYSQFQTAESENRSYEGTLYKKGAFMKPWKARWFVLDKTKHQLRYYDHRADTECKGVIDLAEVEAVAPGTPAMGAPKTVDEKAFFDVKTTRRVYNFCAQDVPSAQQWVDQIQSCLSDA", "length": 1863, "header": "tr|G5E5Q8-1|G5E5Q8_BOVIN Isoform 1 of SET binding factor 1 OS=Bos taurus OX=9913 GN=SBF1 PE=3 SV=2 CANONICAL=G5E5Q8-1" }, "isoforms": [ { "isoform_ac": "A0A3Q1M4Y7-1", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1M4Y7/entry", "sequence": { "sequence": "MARLADYFVLVAFGPHPRGSGEGQGQILQRFPEKDWEDNPFPQGIELFCQPSGWQLCPERNPPTFFVAVLTDINSERHYCACLTFWEPVEPTQEELCARDAAERDEEANEGGPGALPPPTPSPPGQLFAPKTLVLVSRLDHVEVFRNSLGLIYTIHVEGLNVGLENVVGNLLTCVIPLAGGSQRTISLGAGDRQVIQTPLTDSLPISRCSVALLFRQLGITNVLSLFCAALTEHKVLFLSRSYQRLSDACRGLLALLFPLRYSFTYVPILPAQLLEVLSTPTPFIIGVNAAFQAEAQELLDVIVADLDGGTVTVPECVHIPPLPEPLQSQTHSILSMVLDPELELADLAFPPPTTSISSLKMQDKELRAVFLRLFAQLLQGYRWCLHMVRIHPEPVIRFHKAAFLGQRGLVEDDFLMKVLEGMAFAGFVSERGVPYRPTDLFDELVAHEVARMRADENHPQRVLRHVKELAEQLYKNENPYPAVAMHKVQRPGEASHLRRAPRPFPRLDEGMVQWIVDQATAKMQGAPPAVKAEKRTTVPSGPPMTAIVERSGGLHGNSARRLEVVRNCISYVFEGKMLEAKKLLPAVLRALKGRAARRCLAQELHLHVQQNRAVLDHQQFDFVVRMMNCCLQDCTSLDEHGIAAALLPLVTAFCRKLSPGVTQFAYSCVQEHVVWSTPQFWEAMFYGDVQTHIRALYLEPAEDRDSFSVGEAPVQEDERSALDVASEQRRLWPTLSREKQQELVQKEESTVFSQAIHYANRMSYLLLPLDSSKSRLLRERAGLGELESASNSLVTNSMAGSVAESYDTESGFEDAETCDVAGAVVRFINRFVDKVCTESGVTSDHLKGLHVMVPDIVQMHIETLEAVHRESKRLPPIQKPKLLRPRLLPGEECVLDGLRVYLLPDGREEGAGGPGGGPALLPAEGAVFLTTYRVIFTGMPTDPLVGEQVVVRSFPVAALTKEKRVSVQTPVDQLLQDGLQLRSCTFQLLKMAFDEEVGSDSAELFRKQLHKLRYPPDIRGTFALSLGSAHTPGRPPRANKDKGPSFRTLSRNLVKNAKKTIGRQYVTRKKYNPPSWEHRGQPPPEDQEDEISVSEELEPSTLTPSSALKPSDRMTMSSLVERACCRDYQRLGLGTLSSSLSRAKSEPFRISPVNRMYAICRSYPGLLIVPQSVQDNALQRVSRCYRQNRFPVVCWRSGRSKAVLLRSGGLHGKGVVGLFKAQNAPSPGQSQADSSSLEQEKYLQAVVSSMPRYADASGRNTLSGFSSAHMGSHVPSPRARVTTLSNPMAASASRRTAPRGKWGSVRASGRSGGLSTDVGSRLAGVGPPQANGAPPEPGFLRPQRAALYIIGDKAQLKGVRPDPLQQWELVPIEVFEARQVKASFKKLLKACVPGCPATEPSPASFLRSLEDSEWLIQIHKLLQVSVLVVELLDSGSSVLVSLEDGWDITTQVVSLVQLLSDPFYRTLEGFRLLVEKEWLSFGHRFSHRGAHTLAGQSSGFTPVFLQFLDCVHQIHLQFPMEFEFSPFYLKFLGYHHVSRRFRTFLLDSDYERIELGLLYEEKGDRRAPQACRSVWEYVERLSKRTPVFYNYMYAPEDAEVLRPYSNVSNLKVWDFYTEETLAEGPPYDWELAQGPPEPPEEERPDGGAPQSRRRVVWPCYDSRPRAQPDAISRLLEEMQRLETELGRPPERWKDAWDRVKAAQRLEGRPDGRGTPSSLLVSSVPHHRRSLGVYLQEGPVGSTLSLSLDSDQSSGSTASSSRQAARRSTSTLYSQFQTAESENRSYEGTLYKKGAFMKPWKARWFVLDKTKHQLRYYDHRADTECKGVIDLAEVEAVAPGTPAMGAPKTVDEKAFFDVKTTRRVYNFCAQDVPSAQQWVDQIQSCLSDA", "length": 1889, "header": "tr|A0A3Q1M4Y7-1|A0A3Q1M4Y7_BOVIN Computationally mapped isoform of SET binding factor 1 OS=Bos taurus OX=9913 GN=SBF1 PE=3 SV=1 CANONICAL=G5E5Q8-1" }, "locus": { "chromosome": "5", "start_pos": 119783902, "end_pos": 119753575, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000075635.2", "url": "https://www.ensembl.org/id/ENSBTAT00000075635.2" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000068689.1", "url": "https://www.ensembl.org/id/ENSBTAP00000068689.1" } ] } }, { "isoform_ac": "A0A3Q1MFD4-1", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1MFD4/entry", "sequence": { "sequence": "MARLADYFVLVAFGPHPRGSGEGQGQILQRFPEKDWEDNPFPQGIELFCQPSGWQLCPERNPPTFFVAVLTDINSERHYCACLTFWEPVEPTQEELCARDAAERDEEANEGGPGALPPPTPSPPGQLFAPKTLVLVSRLDHVEVFRNSLGLIYTIHVEGLNVGLENVVGNLLTCVIPLAGGSQRTISLGAGDRQVIQTPLTDSLPISRCSVALLFRQLGITNVLSLFCAALTEHKVLFLSRSYQRLSDACRGLLALLFPLRYSFTYVPILPAQLLEVLSTPTPFIIGVNAAFQAEAQELLDVIVADLDGGTVTVPECVHIPPLPEPLQSQTHSILSMVLDPELELADLAFPPPTTSISSLKMQAAFLGQRGLVEDDFLMKVLEGMAFAGFVSERGVPYRPTDLFDELVAHEVARMRADENHPQRVLRHVKELAEQLYKNENPYPAVAMHKVQRPGEASHLRRAPRPFPRLDEGMVQWIVDQATAKMQGAPPAVKAEKRTTVPSGPPMTAIVERSGGLHGNSARRLEVVRNCISYVFEGKMLEAKKLLPAVLRALKGRAARRCLAQELHLHVQQNRAVLDHQQFDFVVRMMNCCLQDCTSLDEHGIAAALLPLVTAFCRKLSPGVTQFAYSCVQEHVVWSTPQFWEAMFYGDVQTHIRALYLEPAEDRDSFSVGEAPVQEDERSALDVASEQRRLWPTLSREKQQELVQKEESTVFSQAIHYANRMSYLLLPLDSSKSRLLRERAGLGELESASNSLVTNSMAGSVAESYDTESGFEDAETCDVAGAVVRFINRFVDKVCTESGVTSDHLKGLHVMVPDIVQMHIETLEAVHRESKRLPPIQKPKLLRPRLLPGEECVLDGLRVYLLPDGREEGAGGPGGGPALLPAEGAVFLTTYRVIFTGMPTDPLVGEQVVVRSFPVAALTKEKRVSVQTPVDQLLQDGLQLRSCTFQLLKMAFDEEVGSDSAELFRKQLHKLRYPPDIRGTFALSLGSAHTPGRPPRANKDKGPSFRTLSRNLVKNAKKTIGRQYVTRKKYNPPSWEHRGQPPPEDQEDEISVSEELEPSTLTPSSALKPSDRMTMSSLVERACCRDYQRLGLGTLSSSLSRAKSEPFRISPVNRMYAICRSYPGLLIVPQSVQDNALQRVSRCYRQNRFPVVCWRSGRSKAVLLRSGGLHGKGVVGLFKAQNAPSPGQSQADSSSLEQEKYLQAVVSSMPRYADASGRNTLSGFSSAHMGSHVPSPRARVTTLSNPMAASASRRTAPRGKWGSVRASGRSGGLSTDVGSRLAGVGPPQANGAPPEPGFLRPQRAALYIIGDKAQLKGVRPDPLQQWELVPIEVFEARQVKASFKKLLKACVPGCPATEPSPASFLRSLEDSEWLIQIHKLLQVSVLVVELLDSGSSVLVSLEDGWDITTQVVSLVQLLSDPFYRTLEGFRLLVEKEWLSFGHRFSHRGAHTLAGQSSGFTPVFLQFLDCVHQIHLQFPMEFEFSPFYLKFLGYHHVSRRFRTFLLDSDYERIELGLLYEEKGDRRAPQACRSVWEYVERLSKRTPVFYNYMYAPEDAEVLRPYSNVSNLKVWDFYTEETLAEGPPYDWELAQGPPEPPEEERPDGGAPQSRRRVVWPCYDSRPRAQPDAISRLLEEMQRLETELGRPPERWKDAWDRVKAAQRLEGRPDGRGTPSSLLVSSVPHHRRSLGVYLQEGPVGSTLSLSLDSDQSSGSTASSSRQAARRSTSTLYSQFQTAESENRSYEGTLYKKGAFMKPWKARWFVLDKTKHQLRYYDHRADTECKGVIDLAEVEAVAPGTPAMGAPKTVDEKAFFDVKTTRRVYNFCAQDVPSAQQWVDQIQSCLSDA", "length": 1851, "header": "tr|A0A3Q1MFD4-1|G5E5Q8_BOVIN Computationally mapped isoform of SET binding factor 1 OS=Bos taurus OX=9913 GN=SBF1 PE=3 SV=2 CANONICAL=G5E5Q8-1" }, "locus": { "chromosome": "5", "start_pos": 119783902, "end_pos": 119753575, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000076654.2", "url": "https://www.ensembl.org/id/ENSBTAT00000076654.2" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000069236.2", "url": "https://www.ensembl.org/id/ENSBTAP00000069236.2" } ] } }, { "isoform_ac": "A0AAA9TF22-1", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TF22/entry", "sequence": { "sequence": "MARLADYFVLVAFGPHPRGSGEGQGQILQRFPEKDWEDNPFPQGIELFCQPSGWQLCPERNPPTFFVAVLTDINSERHYCACLTFWEPVEPTQEELCARDAAERDEEANEGGPGALPPPTPSPPGQLFAPKTLVLVSRLDHVEVFRNSLGLIYTIHVEGLNVGLENVVGNLLTCVIPLAGGSQRTISLGAGDRQVIQTPLTDSLPISRCSVALLFRQLGITNVLSLFCAALTEHKVLFLSRSYQRLSDACRGLLALLFPLRYSFTYVPILPAQLLEVLSTPTPFIIGVNAAFQAEAQELLDVIVADLDGGTVTVPECVHIPPLPEPLQSQTHSILSMVLDPELELADLAFPPPTTSISSLKMQDKELRAVFLRLFAQLLQGYRWCLHMVRIHPEPVIRFHKAAFLGQRGLVEDDFLMKVLEGMAFAGFVSERGVPYRPTDLFDELVAHEVARMRADENHPQRVLRHVKELAEQLYKNVRRVTQAMGWPGEAILLPLRGHSPTLPVSPQENPYPAVAMHKVQRPGEASHLRRAPRPFPRLDEGMVQWIVDQATAKMQGAPPAVKAEKRTTVPSGPPMTAIVERSGGLHGNSARRLEVVRNCISYVFEGKMLEAKKLLPAVLRALKGRAARRCLAQELHLHVQQNRAVLDHQQFDFVVRMMNCCLQDCTSLDEHGIAAALLPLVTAFCRKLSPGVTQFAYSCVQEHVVWSTPQFWEAMFYGDVQTHIRALYLEPAEDRDSFSVGEAPVQEDERSALDVASEQRRLWPTLSREKQQELVQKEESTVFSQAIHYANRMSYLLLPLDSSKSRLLRERAGLGELESASNSLVTNSMAGSVAESYDTESGFEDAETCDVAGAVVRFINRFVDKVCTESGVTSDHLKGLHVMVPDIVQMHIETLEAVHRESKRLPPIQKPKLLRPRLLPGEECVLDGLRVYLLPDGREEGAGGPGGGPALLPAEGAVFLTTYRVIFTGMPTDPLVGEQVVVRSFPVAALTKEKRVSVQTPVDQLLQDGLQLRSCTFQLLKMAFDEEVGSDSAELFRKQLHKLRYPPDIRGTFALSLGSAHTPGRPPRANKDKGPSFRTLSRNLVKNAKKTIGRQYVTRKKYNPPSWEHRGQPPPEDQEDEISVSEELEPSTLTPSSALKPSDRMTMSSLVERACCRDYQRLGLGTLSSSLSRAKSEPFRISPVNRMYAICRSYPGLLIVPQSVQDNALQRVSRCYRQNRFPVVCWRSGRSKAVLLRSGGLHGKGVVGLFKAQNAPSPGQSQADSSSLEQEKYLQAVVSSMPRYADASGRNTLSGFSSAHMGSHVPSPRARVTTLSNPMAASASRRTAPRGKWGSVRASGRSGGLSTDVGSRLAGVGPPQANGAPPEPGFLRPQRAALYIIGDKAQLKGVRPDPLQQWELVPIEVFEARQVKASFKKLLKACVPGCPATEPSPASFLRSLEDSEWLIQIHKLLQVSVLVVELLDSGSSVLVSLEDGWDITTQVVSLVQLLSDPFYRTLEGFRLLVEKEWLSFGHRFSHRGAHTLAGQSSGFTPVFLQFLDCVHQIHLQFPMEFEFSPFYLKFLGYHHVSRRFRTFLLDSDYERIELGLLYEEKGDRRAPQACRSVWEYVERLSKRTPVFYNYMYAPEDAEVLRPYSNVSNLKVWDFYTEETLAEGPPYDWELAQGPPEPPEEERPDGGAPQSRRRVVWPCYDSRPRAQPDAISRLLESPAFSFLAVHTPVWTALCWTPAAWCLFREAWGGLSGRSC", "length": 1747, "header": "tr|A0AAA9TF22-1|G5E5Q8_BOVIN Computationally mapped isoform of SET binding factor 1 OS=Bos taurus OX=9913 GN=SBF1 PE=3 SV=1 CANONICAL=G5E5Q8-1" }, "locus": { "chromosome": "5", "start_pos": 119783902, "end_pos": 119763605, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000124673.1", "url": "https://www.ensembl.org/id/ENSBTAT00000124673.1" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000095444.1", "url": "https://www.ensembl.org/id/ENSBTAP00000095444.1" } ] } }, { "isoform_ac": "G5E5Q8-1", "url": "https://www.uniprot.org/uniprotkb/G5E5Q8/entry", "sequence": { "sequence": "MARLADYFVLVAFGPHPRGSGEGQGQILQRFPEKDWEDNPFPQGIELFCQPSGWQLCPERNPPTFFVAVLTDINSERHYCACLTFWEPVEPTQEELCARDAAERDEEANEGGPGALPPPTPSPPGQLFAPKTLVLVSRLDHVEVFRNSLGLIYTIHVEGLNVGLENVVGNLLTCVIPLAGGSQRTISLGAGDRQVIQTPLTDSLPISRCSVALLFRQLGITNVLSLFCAALTEHKVLFLSRSYQRLSDACRGLLALLFPLRYSFTYVPILPAQLLEVLSTPTPFIIGVNAAFQAEAQELLDVIVADLDGGTVTVPECVHIPPLPEPLQSQTHSILSMVLDPELELADLAFPPPTTSISSLKMQDKELRAVFLRLFAQLLQGYRWCLHMVRIHPEPVIRFHKAAFLGQRGLVEDDFLMKVLEGMAFAGFVSERGVPYRPTDLFDELVAHEVARMRADENHPQRVLRHVKELAEQLYKNENPYPAVAMHKVQRPGEASHLRRAPRPFPRLDEGMVQWIVDQATAKMQGAPPAVKAEKRTTVPSGPPMTAIVERSGGLHGNSARRLEVVRNCISYVFEGKMLEAKKLLPAVLRALKGRAARRCLAQELHLHVQQNRAVLDHQQFDFVVRMMNCCLQDCTSLDEHGIAAALLPLVTAFCRKLSPGVTQFAYSCVQEHVVWSTPQFWEAMFYGDVQTHIRALYLEPAEDRDSFSVGEAPVQEDERSALDVASEQRRLWPTLSREKQQELVQKEESTVFSQAIHYANRMSYLLLPLDSSKSRLLRERAGLGELESASNSLVTNSMAGSVAESYDTESGFEDAETCDVAGAVVRFINRFVDKVCTESGVTSDHLKGLHVMVPDIVQMHIETLEAVHRESKRLPPIQKPKLLRPRLLPGEECVLDGLRVYLLPDGREEGAGGPGGGPALLPAEGAVFLTTYRVIFTGMPTDPLVGEQVVVRSFPVAALTKEKRVSVQTPVDQLLQDGLQLRSCTFQLLKMAFDEEVGSDSAELFRKQLHKLRYPPDIRGTFALSLGSAHTPGRPPRANKDKGPSFRTLSRNLVKNAKKTIGRQYVTRKKYNPPSWEHRGQPPPEDQEDEISVSEELEPSTLTPSSALKPSDRMTMSSLVERACCRDYQRLGLGTLSSSLSRAKSEPFRISPVNRMYAICRSYPGLLIVPQSVQDNALQRVSRCYRQNRFPVVCWRSGRSKAVLLRSGGLHGKGVVGLFKAQNAPSPGQSQADSSSLEQEKYLQAVVSSMPRYADASGRNTLSGFSSAHMGSHGKWGSVRASGRSGGLSTDVGSRLAGVGPPQANGAPPEPGFLRPQRAALYIIGDKAQLKGVRPDPLQQWELVPIEVFEARQVKASFKKLLKACVPGCPATEPSPASFLRSLEDSEWLIQIHKLLQVSVLVVELLDSGSSVLVSLEDGWDITTQVVSLVQLLSDPFYRTLEGFRLLVEKEWLSFGHRFSHRGAHTLAGQSSGFTPVFLQFLDCVHQIHLQFPMEFEFSPFYLKFLGYHHVSRRFRTFLLDSDYERIELGLLYEEKGDRRAPQACRSVWEYVERLSKRTPVFYNYMYAPEDAEVLRPYSNVSNLKVWDFYTEETLAEGPPYDWELAQGPPEPPEEERPDGGAPQSRRRVVWPCYDSRPRAQPDAISRLLEEMQRLETELGRPPERWKDAWDRVKAAQRLEGRPDGRGTPSSLLVSSVPHHRRSLGVYLQEGPVGSTLSLSLDSDQSSGSTASSSRQAARRSTSTLYSQFQTAESENRSYEGTLYKKGAFMKPWKARWFVLDKTKHQLRYYDHRADTECKGVIDLAEVEAVAPGTPAMGAPKTVDEKAFFDVKTTRRVYNFCAQDVPSAQQWVDQIQSCLSDA", "length": 1863, "header": "tr|G5E5Q8-1|G5E5Q8_BOVIN Isoform 1 of SET binding factor 1 OS=Bos taurus OX=9913 GN=SBF1 PE=3 SV=2 CANONICAL=G5E5Q8-1" }, "locus": { "chromosome": "5", "start_pos": 119783902, "end_pos": 119753575, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000028448.7", "url": "https://www.ensembl.org/id/ENSBTAT00000028448.7" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000028448.6", "url": "https://www.ensembl.org/id/ENSBTAP00000028448.6" } ] } } ], "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "other", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 120, "start_aa": "Thr", "end_pos": 120, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr120", "evidence": [ { "id": "", "database": "GlyGen", "url": "https://data.glygen.org/" } ], "filter_code": "000000000000000010000.00000000001000.0.01000" }, { "glytoucan_ac": "", "type": "O-linked", "subtype": "other", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 1815, "start_aa": "Thr", "end_pos": 1815, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr1815", "evidence": [ { "id": "", "database": "GlyGen", "url": "https://data.glygen.org/" } ], "filter_code": "000000000000000010000.00000000001000.0.01000" } ], "phosphorylation": [], "glycation": [], "keywords": [ "glycoprotein", "glycoprotein_predicted" ], "publication": [], "pathway": [ { "id": "R-BTA-1483248", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-BTA-1483248", "resource": "Reactome", "description": "Synthesis of PIPs at the ER membrane" }, { "id": "R-BTA-8876198", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-BTA-8876198", "resource": "Reactome", "description": "RAB GEFs exchange GTP for GDP on RABs" } ], "orthologs": [ { "uniprot_canonical_ac": "A0A2R8PWA9-1", "protein_name": "Myotubularin-related protein 5 isoform X1", "gene_name": "sbf1", "tax_id": 7955, "organism": "Danio rerio", "sequence": { "sequence": "MARLADYFVVVGYDLDKRGGSEGQGRIHQRFPEKDWEDNPFPQGLELFCQPSGWQLAPERKPSSFFVAVLTDINSERHYCACFTFWESVENPQLQKGEPSEADEDDSPDVLQPAQLYAPRSLVLVSRLDHTEVFRNCLSLIYTVHVDGLTVPMETVIGNLLTCIIPIAGGSQINDPPLCSLSDWLLGCFQPGQEDREESSRTITLGAGDRQVIQTPINDSLPVSGCSVAQLFRQLGIVNVLCLFCAALTEHKILFLSSSYQRLTDACRALLAIMFPLKYSFTYVPILPGKLLEVLSSPTPFIIGVNSHFRSETQELLDVIIADLDGGTVTIPECVHISVLPEPLLHHTQTAISMVLDPELEVADHAFPPPSIQPSALKIQDKEIRAVFLWLFSQLFQGYRWCLHIIRIHPEPVIRFHKAAFLGQRALSEDDFLMKVLDGMAFAGFVSERGPPYRATDLFDDLIANQVERIRKETGDPHKVMKHIKELAEQLFKNENPYPAVTMHRVQRTAESAHPRLPQTSFPLLDEVAVQLFIDHATAKLKTAPPVVKAELKSMVPTGPPLVDFVDRNGNVLANSARRLEVVRNCITYIFDNKMLEAKKLMPAVLRALKGRAARVCLTQELNLHVLQNRAVLDDQQFDYIVRMMNCTLQDCSHMDEHGIAAALLPLVTAFCRKLGGGITQFAYSCVQEHMVWTNMQFWEAMFYSDVQKHIRTLYLENGEEGDASSPEVEGLGVSQNQLSALELASEQSRLWPTLSKEQQQERVQKEESTVFSQAIHYANRMSYLLLPLDTSKNRLLRNTGLGDVESVSNSYVTNSIAGSMAESYDTESGFEDAESSDVANSVVRFINRFVDKVCNESGVTNEHLKALHTMIPDIVQMHIETLDAVHRESKRLPPIQKPKLLRPTLLPGEEFVMDGMRVHLITDGREEATGSMGGPPLLPAEGAIFLTSYRLIFKGTPTDPLVGEQVVTRSFPVASLTKEKRISVSLPMDQFIQEGLQLRSCTFQLMKIAFDEEVASDLAEVFRKHMHKLRYPQHVQGTFAFTVGQSAKLVVEHKTKDKNQSLKTLSRNLVKTAKRTIGRQYVTRKKYSPPTWENRSSMQSEMDEDEISVSEEPEPSSLTLSSTIRSSDRQTMSNVVERACCRDYQRLGLGTLSNSLTRSKNEPFRISTVNRMYTVCRSYPGLLIVPQSIPDSTIQRICRCYRQNRFPVVCWRNSRTKAVLLRSAGLHAKGVVGFFKSPNAPTAGPSQADSTSLEQEKYLQAIISSMPSYSETSGRNTLSGFTSSHMSTSDSSDKLRQPKIGALMKQVMGAKEDVPGTFSRGALGQRARVVSLSQPRVSVKARNSPRGKWGSIRGSGRLSTYNPDVGNRLAGKESPQANGGPSETYFLRQQRAYLFIIGDKSQLKGGKQDSFQQWEVVPIEVFDVRQVKNSFKKLMKACVPSSLSFDANMTFHRCLEESEWMNLLHRVLQVSVLVVELLDNGSSVMVSLEDGWDVTTQVVSLVQLLSDPYYRTIDGFRLLVEKEWLSFGHRFSHRGAQTLASQSSGFTPVFLQFLDCVHQIHLQFPMEFEFSQYYLKFLAYHYVSNRFRTFLLDSDYERIELGVLYEEKGERKSTQVCKSVWDYIDRLNKKTPIFYNYMFSPEEEEVLKPYSFVSNLKVWDFYTEETLSEGPSFDWELVQGRQEKPQEEAGDKQETTAPKSKRRIVWPCYDNLSKVVPDAITKLLQDVQNLETELGQPTEKWKDTWDKIKTTQRVESRLESRHSFSSSLLMSSNLSHQRRSQGVYLQESGVGSSINLALDCEVSATSTPAAGRPSTSTLYSQFQSTESENRSFEGILYKKGALLKPWKPRWFVLDKTKHQLRYYETRQDKECKGMIELADVESVIPGTPAMGAPKNIDDKAFFDLKTTKRVYNFCAQDSSNAQSWMDSIQGCLSDA", "length": 1936 }, "evidence": [ { "id": "G5E5Q8", "url": "https://omabrowser.org/oma/group/G5E5Q8/", "database": "OMA" } ], "glygen_name": "Zebrafish", "common_name": "Zebrafish" }, { "uniprot_canonical_ac": "M0RAP5-1", "protein_name": "SET binding factor 1", "gene_name": "Sbf1", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MARLADYFVLVAFGPHPRGSGEGQGQILQRFPEKDWEDNPFPQGIELFCQPSGWQLCPERNPPTFFVAVLTDINSERHYCACLTFWEPVESTQEVMCTEDATEKEEEAHGGGQAQLSSTAPAQPGQLFAPKTLVLVSRLDHADVFRNSLGLIYTIHVEGLNVNLENVIGNLLTCTVPLAGGSQRTISLGAGDRQVIQTPLVDSLPVSRCSVALLFRQLGITNVLSLFCAALTEHKVLFLSRSYQRLADACRGLLALLFPLRYSFTYVPILPAQLLEVLSTPTPFIIGVNAAFQAETQELLDVIVADLDGGTVTVPECVHIPPLPEPLQSQTHNVLSMVLDPELELADLAFPPPTTSASSLKMQDKELRAVFLRLFAQLLQGYRWCLHIVRIHPEPVIRFHKAAFLGQRGLVEDDFLMKVLEGMAFAGFVSERGVPYRSTDLFDELVAHEVARMRADENHPHRVLRHVQELAEQLYKNENPYPAVAMHKVQRPGEASHLRRTHRPFPRLDEGTVQWIVDQAAAKMQGAPPAVKAERRTTVPSGPPMTAILERCSGPHINSARRLEVVRNCISYVFEGKMLEAKKLLPAVLRALKGRAARRCLAHELHLHVQQNRAVLDHQQFDFVVRMMNCCLQDCTSLDEHGIAAALLPLVTAFCRKLSPGVTQFAYSCVQEHVVWSTPQFWEAMFYGDVQTHIRALYLEPSDGVSPTQETGEAQSQDDERSALDVASEQRRLWPTLSREKQQELVQKEESTVFSQAIHYANRMSYLLLPLDSSKSRLLRERAGLGDLESASNSLVTNSMAGSVAESYDTESGFEDAETCDVAGAVVRFINRFVDKVCTESGVTSDHLKGLHVMVPDIVQMHIETLEAVHRESKRLPPIQKPKLLRPRLLPGEECVLDGLRVYLLPDGREEGVGGSGGGPALLPAEGAVFLTTYRVIFTGMPTDPLVGEQVVVRSFPVAALTKEKRISVQTPVDQLLQDGLQLRSCTFQLLKMAFDEEVGSDSAELFRKQLHKLRYPPDIRATFAFTLGSALTPGRPPRVTKDKGPSFRTLSRNLVKNAKKTIGRQYVTRKKYNPPGWEHRGQPPPEDQEDEISVSEELEPSTLTPSSALKPSDRMTMSSLVERACCRDYQRLGLGTLSSSLSRAKSEPFRISPVNRMYAICRSYPGLLIVPQSIQDNALQRVSRCYRQNRFPVVCWRSGRSKAVLLRSGGLHGKGVVGLFKAQNTPSPGQAQADSSSLEQEKYLQAVVSSMPRYADSSGRNTLSSFSSAHMGGHVPSPRARVTTLSNPLAASASRWTASRGKWSSVRASGRSSGLGADVGSRLAGRDLLSTPHTNGAPPDSGFLRPQRAALYIIGDKAQLKGVRPDPLQQWELVPIEVFEARQVKASFKKLLKACVPGCPATEPSPASFLRSLEDSEWLIQIHKLLQISVLVVELLDSGSSVLVSLEDGWDITTQVVSLVQLLSDPFYRTLEGFRLLVEKEWLSFGHRFSHRGAHTLAGQSSGFTPVFLQFLDCVHQVHLQFPMEFEFSQFYLKFLGYHHTSRRFRTFLLDSDYERIELGLLYEEKGERRGQLACKSVWEYVDRLSKRTPMFYNYTYAPEDTEVLRPYSNVSNLKVWDFYTEETLAEGPPYDWELAQGPPEPPEEERPDGGAPQSRRRVVWPCYDSRPRVQPDAISRLLEELQRLETELGRPSERWKETWDRVKAAQRLEGRQDGRGTPSSLLVSAVPHHRRSLGVYLQEGPVGSTLSLSLDSDQSSGSTTSSSRQAARRSTSTLYSQFQTAESENRSYEGTLYKKGAFMKPWKARWFVLDKTKHQLRYYDHRVDTECKGVIDLAEVEAVAPGTPTIGAPKTVDEKAFFDVKTTRRVYNFCAQDVPSAQQWVDRIQSCLSDA", "length": 1893 }, "evidence": [ { "id": "G5E5Q8", "url": "https://omabrowser.org/oma/group/G5E5Q8/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "O95248-1", "protein_name": "Myotubularin-related protein 5", "gene_name": "SBF1", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MARLADYFVLVAFGPHPRGSGEGQGQILQRFPEKDWEDNPFPQGIELFCQPSGWQLCPERNPPTFFVAVLTDINSERHYCACLTFWEPAEPSQQETTRVEDATEREEEGDEGGQTHLSPTAPAPSAQLFAPKTLVLVSRLDHTEVFRNSLGLIYAIHVEGLNVCLENVIGNLLTCTVPLAGGSQRTISLGAGDRQVIQTPLADSLPVSRCSVALLFRQLGITNVLSLFCAALTEHKVLFLSRSYQRLADACRGLLALLFPLRYSFTYVPILPAQLLEVLSTPTPFIIGVNAAFQAETQELLDVIVADLDGGTVTIPECVHIPPLPEPLQSQTHSVLSMVLDPELELADLAFPPPTTSTSSLKMQDKELRAVFLRLFAQLLQGYRWCLHVVRIHPEPVIRFHKAAFLGQRGLVEDDFLMKVLEGMAFAGFVSERGVPYRPTDLFDELVAHEVARMRADENHPQRVLRHVQELAEQLYKNENPYPAVAMHKVQRPGESSHLRRVPRPFPRLDEGTVQWIVDQAAAKMQGAPPAVKAERRTTVPSGPPMTAILERCSGLHVNSARRLEVVRNCISYVFEGKMLEAKKLLPAVLRALKGRAARRCLAQELHLHVQQNRAVLDHQQFDFVVRMMNCCLQDCTSLDEHGIAAALLPLVTAFCRKLSPGVTQFAYSCVQEHVVWSTPQFWEAMFYGDVQTHIRALYLEPTEDLAPAQEVGEAPSQEDERSALDVASEQRRLWPTLSREKQQELVQKEESTVFSQAIHYANRMSYLLLPLDSSKSRLLRERAGLGDLESASNSLVTNSMAGSVAESYDTESGFEDAETCDVAGAVVRFINRFVDKVCTESGVTSDHLKGLHVMVPDIVQMHIETLEAVQRESRRLPPIQKPKLLRPRLLPGEECVLDGLRVYLLPDGREEGAGGSAGGPALLPAEGAVFLTTYRVIFTGMPTDPLVGEQVVVRSFPVAALTKEKRISVQTPVDQLLQDGLQLRSCTFQLLKMAFDEEVGSDSAELFRKQLHKLRYPPDIRATFAFTLGSAHTPGRPPRVTKDKGPSLRTLSRNLVKNAKKTIGRQHVTRKKYNPPSWEHRGQPPPEDQEDEISVSEELEPSTLTPSSALKPSDRMTMSSLVERACCRDYQRLGLGTLSSSLSRAKSEPFRISPVNRMYAICRSYPGLLIVPQSVQDNALQRVSRCYRQNRFPVVCWRSGRSKAVLLRSGGLHGKGVVGLFKAQNAPSPGQSQADSSSLEQEKYLQAVVSSMPRYADASGRNTLSGFSSAHMGSHGKWGSVRTSGRSSGLGTDVGSRLAGRDALAPPQANGGPPDPGFLRPQRAALYILGDKAQLKGVRSDPLQQWELVPIEVFEARQVKASFKKLLKACVPGCPAAEPSPASFLRSLEDSEWLIQIHKLLQVSVLVVELLDSGSSVLVGLEDGWDITTQVVSLVQLLSDPFYRTLEGFRLLVEKEWLSFGHRFSHRGAHTLAGQSSGFTPVFLQFLDCVHQVHLQFPMEFEFSQFYLKFLGYHHVSRRFRTFLLDSDYERIELGLLYEEKGERRGQVPCRSVWEYVDRLSKRTPVFHNYMYAPEDAEVLRPYSNVSNLKVWDFYTEETLAEGPPYDWELAQGPPEPPEEERSDGGAPQSRRRVVWPCYDSCPRAQPDAISRLLEELQRLETELGQPAERWKDTWDRVKAAQRLEGRPDGRGTPSSLLVSTAPHHRRSLGVYLQEGPVGSTLSLSLDSDQSSGSTTSGSRQAARRSTSTLYSQFQTAESENRSYEGTLYKKGAFMKPWKARWFVLDKTKHQLRYYDHRVDTECKGVIDLAEVEAVAPGTPTMGAPKTVDEKAFFDVKTTRRVYNFCAQDVPSAQQWVDRIQSCLSDA", "length": 1868 }, "evidence": [ { "id": "G5E5Q8", "url": "https://omabrowser.org/oma/group/G5E5Q8/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "Q6ZPE2-1", "protein_name": "Myotubularin-related protein 5", "gene_name": "Sbf1", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MARLADYFVLVAFGPHPRGSGEGQGQILQRFPEKDWEDNPFPQGIELFCQPSGWQLCPERNPPTFFVAVLTDINSERHYCACLTFWEPVESTQEVVCTDNATEKEEEADGGGQARLSSTAPAQPGQLFAPKTLVLVSRLDHAEVFRNSLGLIYAIHVEGLNVSLENVIGNLLTCTVPLAGGSQRTISLGAGDRQVIQTPLVDSLPVSRCSVALLFRQLGITNVLSLFCAALTEHKVLFLSRSYQRLADACRGLLALLFPLRYSFTYVPILPAQLLEVLSTPTPFIIGVNAAFQAETQELLDVIVADLDGGTVTVPECVHIPPLPEPLQSQTHNVLSMVLDPELELADLAFPPPTTSASSLKMQDKELRAVFLRLFAQLLQGYRWCLHIVRIHPEPVIRFHKAAFLGQRGLVEDDFLMKVLEGMAFAGFVSERGVPYRATDLFDELVAHEVARMRADESHPHRVLRHVQELAEQLYKNENPYPAVAMHKVQRPGEASHLRRTHRPFPRLDEGTIQWIVDQAAAKMQGAPPAVKAERRSTVPSGPPMTAILERCSGPHINSARRLEVVRNCISYVFEGKMLEAKKLLPAVLRALKGRAARRCLAHELHLHVQQNRAVLDHQQFDFVVRMMNCCLQDCTSLDEHGIASALLPLVTAFCRKLSPGVTQFAYSCVQEHVVWSTPQFWEAMFYGDVQTHIRALYLEPSDGVSPTQETGEAQSQDDERSALDVASEQRRLWPTLSREKQQELVQKEESTVFSQAIHYANRMSYLLLPLDSSKSRLLRERAGLGDLESASNSLVTNSMAGSVAESYDTESGFEDAETCDVAGAVVRFINRFVDKVCTESGVTSDHLKGLHVMVPDIVQMHIETLEAVHRESKRLPPIQKPKLLRPRLLPGEECVLDGLRVYLLPDGREEGVGGSGGGPALLPAEGAVFLTTYRVIFTGMPTDPLVGEQVVVRSFPVAALTKEKRISVQTPVDQLLQDGLQLRSCTFQLLKMAFDEEVGSDSAELFRKQLHKLRYPPDIRATFAFTLGSAHTPGRPPRVTKDKGPSFRTLSRNLMKNAKKTIGRQYVTRKKYNPPGWEHRGQPPPEDQEDEISVSEELEPSTLTPSSALKPSDRMTMSSLVERACCRDYQRLGLGTLSSSLSRAKSEPFRISPVNRMYAICRSYPGLLIVPQSIQDNALQRVSRCYRQNRFPVVCWRSGRSKAVLLRSGGLHGKGVVGLFKAQNTPSPGQAQADSSSLEQEKYLQAVVSSMPRYADSSGRNTLSSFSSAHMGGHGKWSSVRASGRSSGLGSDVGSRLAGRDLLSTPHTNGAPPDSGFLRPQRAALYIIGDKAQLKGVRPDPLQQWELVPIEVFEARQVKASFKKLLKACVPGCPATEPSPASFLRSLEDSEWLIQIHKLLQISVLVVELLDSGSSVLVSLEDGWDITTQVVSLVQLLSDPFYRTLEGFRLLVEKEWLSFGHRFSHRGAHTLAGQSSGFTPVFLQFLDCVHQVHLQFPMEFEFSQFYLKFLGYHHTSRRFRTFLLDSDYERIELGLLYEEKGERRGQLACKSVWEYVDRLSKRTPMFYNYTYAPEDTEVLRPYSNVSNLKVWDFYTEETLAEGPPYDWELAQGPPEPPEEERPDGGAPQSRRRVVWPCYDSRPRVQPDAISRLLEELQRLETELGRPSERWKDTWDRVKAAQRLESRQDGRGTPSSLLVSAVPHHRRSLGVYLQEGPVGSTLSLSLDSDQSSGSTTSSSRQAARRSTSTLYSQFQTAESENRSYEGILYKKGAFMKPWKARWFVLDKTKHQLRYYDHRMDTECKGVIDLAEVEAVAPGTPTIGAPKTVDEKAFFDVKTTRRVYNFCAQDVPSAQQWVDRIQSCLSDA", "length": 1867 }, "evidence": [ { "id": "G5E5Q8", "url": "https://omabrowser.org/oma/group/G5E5Q8/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q9VGH9-1", "protein_name": "SET domain binding factor, isoform A", "gene_name": "Sbf", "tax_id": 7227, "organism": "Drosophila melanogaster", "sequence": { "sequence": "MSRLADYFVIVGYDSDKEKTASNVGGQPTCGKIVQRFPEKDWPDTPFIEGIEWFCQPLGWSLSYEKQEPKFFVSVLTDIDANKHYCACLSFHETVAITQTRSVDDEDETIGSSRLLGATPSSMDGITTTSTPASITHHSVMYAPKCLVLISRLDCAETFKNCLGTIYTVYIENLAYGLETLIGNILGCIQVPPAGGPQVRFSIGAGDKQSLQPPQSSSLPTTGSGVHFLFKQLGIKNVLILLCSVMTENKILFLSKCYWHLTDSCRALVALMYPFRYTHVYIPILPAPLTEVLSTPTPFIMGIHSSLQTEITDLLDVIVVDLDGGLVTIPESLTPPVPILPSPLWEQTQDLLSMILFPNLAQADLAFPTLERPSAIAKTDAQIDKELRAIFMRLFAQLLQGYRSCLTIIRIHPKPVITFHKAGFLGARDLIESEFLFRVLDSMFFTTFVNERGPPWRSSDAWDELYSSMNELLKSEAQNRNLVGRTQRFKGYFNFTFPSYFQILTHIQELGRVLYENEGTLAHISYAQKVLRPPEGAFQRIHQPAFPRISSEKVELIIQEGIRKNGVPQRFHVTRNQHRIIPMGPRLPEALDVRPNVQNSARRLEVLRICVSYIFENRITDARKLLPAVMRTLMHRDARLILCREFFGYVHGNKAVLDHQQFELVVRFMNKALQKSSGIDEYTVAAALLPMSTIFCRKLSTGVVQFAYTEIQDHAIWKNLQFWESTFFQDVQGQIKALYLLHRRQNEHQKEANCVLDEVPLEEPTALEITAEQLRKSPNIEEEKKAELAKSEESTLYSQAIHFANRMVSLLIPLDVNVDAASKPKPAFRLEENQSVSNSIMGSHSLSEHSDEGFEENNALEIGVTVGKTISRFIDCVCTEGGVTSEHIRNLHDMVPGVVHMHIESLEPVYLEAKRHPHVQKPKIQTPCLLPGEDLVTDHLRCFLMPDGREDETQCLIPAEGALFLTNYRVIFKGSPCDPLFCEQVIVRTFPIASLLKEKKISVLYLAHLDQTLTEGLQLRSSSFQLIKVAFDPEVTPEQIESFRKILSKARHPFDEFEYFAFQSYGTMLQGVAPLKTKEKYSTLKGFAKKTLLRGAKKAGFKQKQQTKRKLVSDYDYGSADAQETQSIDDELEDGDEFETQNNAMPRLLTTKDVERMRERSYVQDWKRLGFDAESQRGFRISNANTSYATCRSYPAIIVAPVQCSDAAIMHLGRCFKGQRIPLPTWRHANGALLIRGGQPNSKSVIGMLKNTTGSTTNAHHDVTHYPEQDKYFLALINTMPKLTPLALNQYSGMNLSMSSLMGHSSSDDRQPLTPELSRKHKNNLDISDGNKSSQGGKGGTMKGNPKNSLAHPFRKMRLYALGEKSQAKSNMNVDFCADFIPVDYPDIRQSRPAFKKLIRACMPSHNTNEADGQSFAKMVEQSDWLQQISSLMQLSGAVVDLIDLQESSVMLSLEDGSDVTAQLSSIAQLCLDPYYRSLDGFRVLVEKEWLAFGHRFAHRSNLKPSHANTNIAFAPTFLQFLDVVHQLQRQFPMAFEFNDFYLRFLAYHSVSCRFRTFLFDCELERSDSGIAAMEDKRGSLNAKHMFGAGGMATNGSDDECSVYPLDIRSQRAPAPLNRIGHSIFDYIERQHNKTPIFYNFLYSGDKSVTLRPQNNVAALDLWCYYTNEELAQGAPYDLEVTTVDDEIDLSETKGKRMVITAGYDNMEKCNPSAYVCLLSEVKQAETERGHLPQKWLQVWNSLEVPQLEPVARNTSLGNIFVQTHQHKRSTLEIIMKGRLAGYQDKYFHPHRFEKHPYTTPTNCNHCTKLLWGPVGYRCMDCGNSYHEKCTEHSMKNCTKYKAIDGAVGPPNVNMSQGDTASIASSAATTARTSSHHFYNQFSSNVAENRTHEGHLYKRGALLKGWKQRWFVLDSIKHQLRYYDTSEDTAPKGIIELAEVQSVTAAQPAQIGAKGVDEKGFFDLKTSKRIYNFYAINANLAQEWIEKLQACLQ", "length": 1993 }, "evidence": [ { "id": "G5E5Q8", "url": "https://omabrowser.org/oma/group/G5E5Q8/", "database": "OMA" } ], "glygen_name": "Fruit fly", "common_name": "Fruit fly" } ], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 3, "go_terms": [ { "name": "cytoplasm", "id": "GO:0005737", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005737", "evidence": [ { "database": "UniProtKB", "id": "G5E5Q8", "url": "https://www.uniprot.org/uniprotkb/G5E5Q8" } ], "pmid": "" }, { "name": "membrane", "id": "GO:0016020", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016020", "evidence": [ { "database": "UniProtKB", "id": "G5E5Q8", "url": "https://www.uniprot.org/uniprotkb/G5E5Q8" } ], "pmid": "" }, { "name": "nuclear body", "id": "GO:0016604", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016604", "evidence": [ { "database": "UniProtKB", "id": "G5E5Q8", "url": "https://www.uniprot.org/uniprotkb/G5E5Q8" } ], "pmid": "" } ] }, { "name": "Molecular Function", "total": 1, "go_terms": [ { "name": "guanyl-nucleotide exchange factor activity", "id": "GO:0005085", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005085", "evidence": [ { "database": "UniProtKB", "id": "G5E5Q8", "url": "https://www.uniprot.org/uniprotkb/G5E5Q8" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 1581, "end_pos": 1583, "annotation": "n_glycosylation_sequon" }, { "start_pos": 1757, "end_pos": 1759, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "G5E5Q8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G5E5Q8" }, { "id": "PS51339", "database": "PROSITE", "url": "https://prosite.expasy.org/PS51339" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "Myotubularin phosphatase", "eco_id": "ECO_0000259", "start_pos": 1119, "end_pos": 1592, "start_aa": "Ser", "end_aa": "Thr", "glycosite_overlap": [] }, { "evidence": [ { "id": "G5E5Q8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G5E5Q8" }, { "id": "PS50003", "database": "PROSITE", "url": "https://prosite.expasy.org/PS50003" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "PH", "eco_id": "ECO_0000259", "start_pos": 1757, "end_pos": 1861, "start_aa": "Asn", "end_aa": "Ser", "glycosite_overlap": [] }, { "evidence": [ { "id": "G5E5Q8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G5E5Q8" }, { "id": "PS50211", "database": "PROSITE", "url": "https://prosite.expasy.org/PS50211" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "UDENN", "eco_id": "ECO_0000259", "start_pos": 7, "end_pos": 439, "start_aa": "Tyr", "end_aa": "Thr", "glycosite_overlap": [] } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" }, { "name": "homologset.oma", "label": "OMA Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [ 120, 1815 ], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 1581, "end_pos": 1583 }, { "start_pos": 1757, "end_pos": 1759 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 2 }, { "field": "total_sites", "count": 2 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 2 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "exact_sites", "count": 2 }, { "field": "exact_o_linked_sites", "count": 2 }, { "field": "fuzzy_sites", "count": 0 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", 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"glycosite_overlap": [] } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 103, "end_pos": 105 }, { "start_pos": 142, "end_pos": 144 }, { "start_pos": 152, "end_pos": 154 }, { "start_pos": 191, "end_pos": 193 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { 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"https://bgee.org/?page=gene&gene_id=ENSBTAG00000004461", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "526925", "url": "https://www.ncbi.nlm.nih.gov/gene/526925", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR006594", "url": "https://www.ebi.ac.uk/interpro/entry/IPR006594", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR055289", "url": "https://www.ebi.ac.uk/interpro/entry/IPR055289", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "A0A3Q1LLL6", "url": "https://www.orthodb.org/?gene=A0A3Q1LLL6", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "F1MB20", "url": "https://www.orthodb.org/?gene=F1MB20", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "G3MYI2", "url": "https://www.orthodb.org/?gene=G3MYI2", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR39063", "url": 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"MHPVLNGKVQSPSISVEESSLLIGASNSLVADHLQRCGYEYSLSVFFPESGLAKEKVFTMQNLLHLFKISPESSLYKSLISGFDKENQKGFLIQFLKELAKYHQNKESCNMETQTSSTFPVKDSLAEKLQLIDNEFAGACPQQPKLESLEIKLNEYKREVEQQLRAEMSQKLKYFKDTEIMKIKMEEKRKYEKELVEFQNEFERTCQAKSEALMSQEKITLERIQKHQENETKEIYAQRQLLLKDIDLLRGREAELKQRIEAFELAQRLQEEKNKSMTDGLRRRELTIKNIEETYDQKLKNELLKYQLELKEDYITRTNRLIEDERKNKEKALHLQEELAALNCKKEELDRSVNRVKELERSIERACPLEPRVVLESLTVCLWARSVTSDPLSLELESVRAQCLALTKQNHMLSEKVKEMSDYSLLKEGKLELQAQNKLLKQQVEDMKSENMHLLNRIAQPSPELLIFQKELKKAENAIAFEHKEFETHKQALQKQLQSEIERSAQLKAQVLEYDASVKRLTTQVSILKLQLKQTQTALENEVYPNPSHSLLNRSISGLMSTRVEPRDGDISGDFLKNPLRQEEVTAGPVTPRIPRYPNASAEGSSPDSDLEFVASTKVRVRELEQEAECLEKAFQNYHQRVSQCPTKSRLAARSPPLLCLPGTLKNITAAVPERCVFMDARVTSQQPPVSTRGGDDSEVSEVPSSMASRSHKSTASRRLSSTPLPKPRSLDSETYLEGLGRSTVTTTCPDRKPQPSPAESRHISVHSLSSPLEQKASLYQRHTELQDKSEFSNPDKLVFKDNEGFEPSFEYGWSVPRQFKREGLHHAGDMPHVDGAAAPVPTRPISFQYPGVNQKSLGEQKEEEKLREQQARERRQGDEQRQSKWQETLQRERRQLEKLDQERRLIEQSLKLEMEKEYESSVQEMKDKSKSVSGENPLEKYMKIMQQNPDEDTTDKSSKKVVRESSQLDTLPSSDTKDKSFAAFSHEEPDDIW", "length": 994, "header": "tr|G3MYI2-1|G3MYI2_BOVIN Isoform 1 of OFD1 centriole and centriolar satellite protein OS=Bos taurus OX=9913 GN=OFD1 PE=4 SV=3 CANONICAL=G3MYI2-1" }, "isoforms": [ { "isoform_ac": "A0A3Q1LLL6-1", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1LLL6/entry", "sequence": { "sequence": "MCDLPRPGIKLMSPIWASRFFTTESPGKPQVFTMQNLLHLFKISPESSLYKSLISGFDKENQKGFLIQFLKELAKYHQNKESCNMETQTSSTFPVKDSLAEKLQLIDNEFAGACPQQPKLESLEIKLNEYKREVEQQLRAEMSQKLKYFKDTEIMKIKMEEKRKYEKELVEFQNEFERTCQAKSEALMSQEKITLERIQKHQENETKEIYAQRQLLLKDIDLLRGREAELKQRIEAFELAQRLQEEKNKSMTDGLRRRELTIKNIEETYDQKLKNELLKYQLELKEDYITRTNRLIEDERKNKEKALHLQEELAALNCKKEELDRSVNRVKELELELESVRAQCLALTKQNHMLSEKVKEMSDYSLLKEGKLELQAQNKLLKQQVEDMKSENMHLLNRIAQPSPELLIFQKELKKAENAIAFEHKEFETHKQALQKQLQSEIERSAQLKAQVLEYDASVKRLTTQVSILKLQLKQTQTALENEVYPNPSHSLLNRSISGLMSTRVEPRDGDISGDFLKNPLRQEEVTAGPVTPRIPRYPNASAEGSSPDSDLEFVASTKVRVRELEQEAECLEKAFQNYHQRVSQCPTKSRLAARSPPLLCLPGTLKNITAAVPERCVFMDARVTSQQPPVSTRGGDDSEVSEVPSSMASRSHKSTASRRLSSTPLPKPRSLDSETYLEGLGRSTVTTTCPDRKPQPSPAESRHISVHSLSSPLEQKASLYQRHTELQDKSEFSNPDKLVFKDNEGFEPSFEYGWSVPRQFKREGLHHAGDMPHVDGAAAPVPTRPISFQYPGVNQKSLGEQKEEEKLREQQARERRQGDEQRQSKWQETLQRERRQLEKLDQERRLIEQSLKLEMEKEYESSVQEMKDKSKSVSGENPLEKYMKIMQQNPDEDTTDKSSKKVVRESSQLDTLPSSDTKDKSFAAFSHEEPDDIW", "length": 935, "header": "tr|A0A3Q1LLL6-1|G3MYI2_BOVIN Computationally mapped isoform of OFD1 centriole and centriolar satellite protein OS=Bos taurus OX=9913 GN=OFD1 PE=4 SV=2 CANONICAL=G3MYI2-1" }, "locus": { "chromosome": "X", "start_pos": 129782997, "end_pos": 129734753, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000083131.2", "url": "https://www.ensembl.org/id/ENSBTAT00000083131.2" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000057673.2", "url": "https://www.ensembl.org/id/ENSBTAP00000057673.2" } ] } }, { "isoform_ac": "F1MB20-1", "url": "https://www.uniprot.org/uniprotkb/F1MB20/entry", "sequence": { "sequence": "MHPVLNGKVQSPSISVEESSLLIGASNSLVADHLQRCGYEYSLSVFFPESGLAKEKVFTMQNLLHLFKISPESSLYKSLISGFDKENQKGFLIQFLKELAKYHQNKESCNMETQTSSTFPVKDSLAEKLQLIDNEFAGACPQQPKLESLEIKLNEYKREVEQQLRAEMSQKLKYFKDTEIMKIKMEEKRKYEKELVEFQNEFERTCQAKSEALMSQEKITLERIQKHQENETKEIYAQRQLLLKDIDLLRGREAELKQRIEAFELAQRLQEEKNKSMTDGLRRRELTIKNIEETYDQKLKNELLKYQLELKEDYITRTNRLIEDERKNKEKALHLQEELAALNCKKEELDRSVNRVKELELELESVRAQCLALTKQNHMLSEKVKEMSDYSLLKEGKLELQAQNKLLKQQVEDMKSENMHLLNRIAQPSPELLIFQKELKKAENAIAFEHKEFETHKQALQKQLQSEIERSAQLKAQVLEYDASVKRLTTQVSILKLQLKQTQTALENEVYPNPSHSLLNRSISGLMSTRVEPRDGDISGDFLKNPLRQEEVTAGPVTPRIPRYPNASAEGSSPDSDLEFVASTKVRVRELEQEAECLEKAFQNYHQRVSQCPTKSRLAARSPPLLCLPGTLKNITAAVPERCVFMDARVTSQQPPVSTRGGDDSEVSEVPSSMASRSHKSTASRRLSSTPLPKPRSLDSETYLEGLGRSTVTTTCPDRKPQPSPAESRHISVHSLSSPLEQKASLYQRHTELQDKSEFSNPDKLVFKDNEGFEPSFEYGWSVPRQFKREGLHHAGDMPHVDGAAAPVPTRPISFQYPGVNQKSLGEQKEEEKLREQQARERRQGDEQRQSKWQETLQRERRQLEKLDQERRLIEQSLKLEMEKEYESSVQEMKDKSKSVSGENPLEKYMKIMQQNPDEDTTDKSSKKVVRESSQLDTLPSSDTKDKSFAAFSHEEPDDIW", "length": 961, "header": "tr|F1MB20-1|G3MYI2_BOVIN Computationally mapped isoform of OFD1 centriole and centriolar satellite protein OS=Bos taurus OX=9913 GN=OFD1 PE=4 SV=3 CANONICAL=G3MYI2-1" }, "locus": { "chromosome": "X", "start_pos": 129786176, "end_pos": 129734753, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000005850.6", "url": "https://www.ensembl.org/id/ENSBTAT00000005850.6" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000005850.6", "url": "https://www.ensembl.org/id/ENSBTAP00000005850.6" } ] } }, { "isoform_ac": "G3MYI2-1", "url": "https://www.uniprot.org/uniprotkb/G3MYI2/entry", "sequence": { "sequence": "MHPVLNGKVQSPSISVEESSLLIGASNSLVADHLQRCGYEYSLSVFFPESGLAKEKVFTMQNLLHLFKISPESSLYKSLISGFDKENQKGFLIQFLKELAKYHQNKESCNMETQTSSTFPVKDSLAEKLQLIDNEFAGACPQQPKLESLEIKLNEYKREVEQQLRAEMSQKLKYFKDTEIMKIKMEEKRKYEKELVEFQNEFERTCQAKSEALMSQEKITLERIQKHQENETKEIYAQRQLLLKDIDLLRGREAELKQRIEAFELAQRLQEEKNKSMTDGLRRRELTIKNIEETYDQKLKNELLKYQLELKEDYITRTNRLIEDERKNKEKALHLQEELAALNCKKEELDRSVNRVKELERSIERACPLEPRVVLESLTVCLWARSVTSDPLSLELESVRAQCLALTKQNHMLSEKVKEMSDYSLLKEGKLELQAQNKLLKQQVEDMKSENMHLLNRIAQPSPELLIFQKELKKAENAIAFEHKEFETHKQALQKQLQSEIERSAQLKAQVLEYDASVKRLTTQVSILKLQLKQTQTALENEVYPNPSHSLLNRSISGLMSTRVEPRDGDISGDFLKNPLRQEEVTAGPVTPRIPRYPNASAEGSSPDSDLEFVASTKVRVRELEQEAECLEKAFQNYHQRVSQCPTKSRLAARSPPLLCLPGTLKNITAAVPERCVFMDARVTSQQPPVSTRGGDDSEVSEVPSSMASRSHKSTASRRLSSTPLPKPRSLDSETYLEGLGRSTVTTTCPDRKPQPSPAESRHISVHSLSSPLEQKASLYQRHTELQDKSEFSNPDKLVFKDNEGFEPSFEYGWSVPRQFKREGLHHAGDMPHVDGAAAPVPTRPISFQYPGVNQKSLGEQKEEEKLREQQARERRQGDEQRQSKWQETLQRERRQLEKLDQERRLIEQSLKLEMEKEYESSVQEMKDKSKSVSGENPLEKYMKIMQQNPDEDTTDKSSKKVVRESSQLDTLPSSDTKDKSFAAFSHEEPDDIW", "length": 994, "header": "tr|G3MYI2-1|G3MYI2_BOVIN Isoform 1 of OFD1 centriole and centriolar satellite protein OS=Bos taurus OX=9913 GN=OFD1 PE=4 SV=3 CANONICAL=G3MYI2-1" }, "locus": { "chromosome": "X", "start_pos": 129786176, "end_pos": 129734753, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000065066.3", "url": "https://www.ensembl.org/id/ENSBTAT00000065066.3" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000054615.3", "url": "https://www.ensembl.org/id/ENSBTAP00000054615.3" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [], "orthologs": [], "go_annotation": {}, "pro_annotation": [], "site_annotation": [ { "start_pos": 230, "end_pos": 232, "annotation": "n_glycosylation_sequon" }, { "start_pos": 274, "end_pos": 276, "annotation": "n_glycosylation_sequon" }, { "start_pos": 553, "end_pos": 555, "annotation": "n_glycosylation_sequon" }, { "start_pos": 599, "end_pos": 601, "annotation": "n_glycosylation_sequon" }, { "start_pos": 667, "end_pos": 669, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 230, "end_pos": 232 }, { "start_pos": 274, "end_pos": 276 }, { "start_pos": 553, "end_pos": 555 }, { "start_pos": 599, "end_pos": 601 }, { "start_pos": 667, "end_pos": 669 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ], "tool_support": { "graph_view": "yes" } }, { "uniprot_canonical_ac": "G3N1R9-1", "uniprot_ac": "G3N1R9", "uniprot_id": "G3N1R9_BOVIN", "mass": { "chemical_mass": 52833.0, "monoisotopic_mass": 52833.0 }, "refseq": {}, "gene_names": [ { "name": "MEIOB", "type": "recommended", "evidence": [ { "id": "G3N1R9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3N1R9" } ] } ], "protein_names": [ { "name": "Meiosis-specific with OB domain-containing protein", "type": "recommended", "evidence": [ { "id": "G3N1R9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3N1R9/entry#names_and_taxonomy" } ] } ], "function": [ { "annotation": "Single-stranded DNA-binding protein required for homologous recombination in meiosis I. Required for double strand breaks (DSBs) repair and crossover formation and promotion of faithful and complete synapsis. Not required for the initial loading of recombinases but required to maintain a proper number of RAD51 and DMC1 foci after the zygotene stage. May act by ensuring the stabilization of recombinases, which is required for successful homology search and meiotic recombination. Displays Single-stranded DNA 3'-5' exonuclease activity in vitro.", "evidence": [ { "database": "UniProtKB", "id": "E1BA02", "url": "https://www.uniprot.org/uniprotkb/E1BA02#function" }, { "database": "UniProtKB", "id": "ARBA00055425", "url": "https://www.uniprot.org/uniprotkb/ARBA00055425#function" }, { "database": "UniProtKB", "id": "A0AAA9SYS6", "url": "https://www.uniprot.org/uniprotkb/A0AAA9SYS6#function" }, { "database": "UniProtKB", "id": "A0AAA9TC93", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TC93#function" }, { "database": "UniProtKB", "id": "A0AAA9TCD2", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TCD2#function" }, { "database": "UniProtKB", "id": "G3N1R9", "url": "https://www.uniprot.org/uniprotkb/G3N1R9#function" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Bos taurus", "taxid": 9913, "evidence": [ { "database": "UniProtKB", "id": "G3N1R9", "url": "https://www.uniprot.org/uniprotkb/G3N1R9" } ], "common_name": "Bovine", "glygen_name": "Bovine", "reference_species": "Bos taurus [9913]" } ], "gene": [ { "name": "MEIOB", "url": "https://www.uniprot.org/uniprotkb/G3N1R9", "locus": { "chromosome": "25", "start_pos": 1395860, "end_pos": 1439098, "strand": "+", "evidence": [ { "database": "Ensembl Gene", "id": "ENSBTAG00000020001", "url": "https://www.ensembl.org/id/ENSBTAG00000020001" } ] } } ], "crossref": [ { "id": "G3N1R9", "url": "https://alphafold.ebi.ac.uk/entry/G3N1R9", "database": "AlphaFoldDB", "categories": [] }, { "id": "ENSBTAG00000020001", "url": "https://bgee.org/?page=gene&gene_id=ENSBTAG00000020001", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "cd04475", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd04475", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "618487", "url": "https://www.ncbi.nlm.nih.gov/gene/618487", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR012340", "url": "https://www.ebi.ac.uk/interpro/entry/IPR012340", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR052469", "url": "https://www.ebi.ac.uk/interpro/entry/IPR052469", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR056880", "url": "https://www.ebi.ac.uk/interpro/entry/IPR056880", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "bta:618487", "url": "https://www.genome.jp/dbget-bin/www_bget?bta:618487", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "E1BA02", "url": "https://www.orthodb.org/?gene=E1BA02", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "G3N1R9", "url": "https://www.orthodb.org/?gene=G3N1R9", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR21166", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR21166", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR21166:SF2", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR21166:SF2", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF24903", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF24903", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "A0AAA9SQW4", "url": "https://www.uniprot.org/uniprotkb/A0AAA9SQW4", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0AAA9SQW4-1", "url": "https://www.uniprot.org/uniprotkb/A0AAA9SQW4-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0AAA9SYS6", "url": "https://www.uniprot.org/uniprotkb/A0AAA9SYS6", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0AAA9SYS6-1", "url": "https://www.uniprot.org/uniprotkb/A0AAA9SYS6-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0AAA9TC93", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TC93", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0AAA9TC93-1", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TC93-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0AAA9TCD2", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TCD2", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0AAA9TCD2-1", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TCD2-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "E1BA02", "url": "https://www.uniprot.org/uniprotkb/E1BA02", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "E1BA02-1", "url": "https://www.uniprot.org/uniprotkb/E1BA02-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "G3N1R9", "url": "https://www.uniprot.org/uniprotkb/G3N1R9", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "G3N1R9-1", "url": "https://www.uniprot.org/uniprotkb/G3N1R9-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MANSIASKNFTALSNLHPNMANLKIIGIVIGKTDVKGFPDRKNIGSERYTFSFTIRDSTTHFVNATSWGSEDYIRSLSDSFRVGECVIIENPLIQTKDLEREEKFSPATPSNYKLLLSENHSTVKLCSSYEVDAKLLSLIYLPVKESCDYYSLGDIVANGHSLDGKIINVLAAVRSVGEPKYFTTSDRRKGQRCEVKLYDETESSFAMICWDSESILLAQSWVPQETVIFAADVRISFDKFRNSMTATVISKTIITTNPDTPEANILLNFIRENKVMNPLDDEIDNYLKESMNLNTIVDVYTVEQLKVKALKNEGKAEPFYGILYAYISTLNIDDETTKVVRNRCSVCGYTVNEASSTCTTCNKDSSGFKSVFLSFDMLIDLTDHTGTLHSCSLTGSVAEETLGCTVDEFLAMTDEQKTALKWQFLLERSKIYLKFFISHRARGGLRVSVLSCKLADSIEASRNLSGQGSVQN", "length": 473, "header": "tr|G3N1R9-1|G3N1R9_BOVIN Isoform 1 of Meiosis-specific with OB domain-containing protein OS=Bos taurus OX=9913 GN=MEIOB PE=3 SV=3 CANONICAL=G3N1R9-1" }, "isoforms": [ { "isoform_ac": "A0AAA9SQW4-1", "url": "https://www.uniprot.org/uniprotkb/A0AAA9SQW4/entry", "sequence": { "sequence": "MANSIASKNFTALSNLHPNMANLKIIGIVIGKTDVKGFPDRKNIGSERYTFSFTIRDSTTHFVNATSWGSEDYIRSLSDSFRVGECVIIENPLIQTKDLEREEKFSPATPSNYKLLLSENHSTVKLCSSYEVDAKLLSLIYLPVKESCDYYSLGDIVANGHSLDGKIINVLAAVRSVGEPKYFTTSDRRKGQRCEVKLYDETESSFAMICWDSESILLAQSWVPQETVIFAADVRISFDKFRNSMTATVISKTIITTNPVNTIVDVYTVEQLKVKALKNEGKAEPFYGILYAYISTLNIDDETTKVVRNRCSVCGYTVNEASSTCTTCNKDSSGFKSVFLSFDMLIDLTDHTGTLHSCSLTGSVAEETLGCTVDEFLAMTDEQKTALKWQFLLERSKIYLKFFISHRARGGLRVSVLSCKLADSIEASRNLSGQGSVQN", "length": 439, "header": "tr|A0AAA9SQW4-1|G3N1R9_BOVIN Computationally mapped isoform of Meiosis-specific with OB domain-containing protein OS=Bos taurus OX=9913 GN=MEIOB PE=3 SV=1 CANONICAL=G3N1R9-1" }, "locus": { "chromosome": "25", "start_pos": 1435203, "end_pos": 1403545, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000123520.1", "url": "https://www.ensembl.org/id/ENSBTAT00000123520.1" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000088728.1", "url": "https://www.ensembl.org/id/ENSBTAP00000088728.1" } ] } }, { "isoform_ac": "A0AAA9SYS6-1", "url": "https://www.uniprot.org/uniprotkb/A0AAA9SYS6/entry", "sequence": { "sequence": "MANSIASKNFTALSNLHPNMANLKIIGIVIGKTDVKGFPDRKNIGSERYTFSFTIRDSTTHFVNATSWGSEDYIRSLSDSFRVGECVIIENPLIQTKDLEREEKFSPATPSNYKLLLSENHSTVKLCSSYEVDAKLLSLIYLPVKESCDYYSLGDIVANGHSLDGKIINVLAAVRSVGEPKYFTTSDRRKGQRCEVKLYDETESSFAMICWDSESILLAQSWVPQETVIFAADVRISFDKFRNSMTATVISKTIITTNPDTPEANILLNFIRENKVMNPLDDEIDNYLKESMNFEQLKVKALKNEGKAEPFYGILYAYISTLNIDDETTKVVRNRCSVCGYTVNEASSTCTTCNKDSSGFKSVFLSFDMLIDLTDHTGTLHSCSLTGSVAEETLGCTFFISHRARGGLRVSVLSCKLADSIEASRNLSGQGSVQN", "length": 435, "header": "tr|A0AAA9SYS6-1|G3N1R9_BOVIN Computationally mapped isoform of Meiosis-specific with OB domain-containing protein OS=Bos taurus OX=9913 GN=MEIOB PE=3 SV=1 CANONICAL=G3N1R9-1" }, "locus": { "chromosome": "25", "start_pos": 1435203, "end_pos": 1403545, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000103718.1", "url": "https://www.ensembl.org/id/ENSBTAT00000103718.1" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000089249.1", "url": "https://www.ensembl.org/id/ENSBTAP00000089249.1" } ] } }, { "isoform_ac": "A0AAA9TC93-1", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TC93/entry", "sequence": { "sequence": "MANSIASKNFTALSNLHPNMANLKIIGIVIGKTDVKGFPDRKNIGSERYTFSFTIRDSTTHFVNATSWGSEDYIRSLSDSFRVGECVIIENPLIQTKDLEREEKFSPATPSNYKLLLSENHSTVKLCSSYEVDAKLLSLIYLPVKESCDYYSLGDIVANGHSLDGKIINVLAAVRSVGEPKYFTTSDRRKGQRCEVKLYDETESSFAMICWDSESILLAQSWVPQETVIFAADVRISFDKFRNSMTATVISKTIITTNPDTPEANILLNFIRENKVMNPLDDEIDNYLKESMNLNTIVDVYTVEQLKVKALKNEGKAEPFYGILYAYISTLNIDDETTKVVRNRCSVCGYTVNEASSTCTTCNKDSSGFKSVFLSFDMLIDLTDHTGTLHSCSLTGSVAEETLGCTFFISHRARGGLRVSVLSCKLADSIEASRNLSGQGSVQN", "length": 444, "header": "tr|A0AAA9TC93-1|G3N1R9_BOVIN Computationally mapped isoform of Meiosis-specific with OB domain-containing protein OS=Bos taurus OX=9913 GN=MEIOB PE=3 SV=1 CANONICAL=G3N1R9-1" }, "locus": { "chromosome": "25", "start_pos": 1435203, "end_pos": 1403545, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000116258.1", "url": "https://www.ensembl.org/id/ENSBTAT00000116258.1" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000094471.1", "url": "https://www.ensembl.org/id/ENSBTAP00000094471.1" } ] } }, { "isoform_ac": "A0AAA9TCD2-1", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TCD2/entry", "sequence": { "sequence": "MANSIASKNFTALSNLHPNMANLKIIGIVIGKTDVKGFPDRKNIGSERYTFSFTIRDSTTHFVNATSWGSEDYIRSLSDSFRVGECVIIENPLIQTKDLEREEKFSPATPSNYKLLLSENHSTVKLCSSYEVDAKLLSLIYLPVKESCDYYSLGDIVANGHSLDGKIINVLAAVRSVGEPKYFTTSDRRKGQRCEVKLYDETESSFAMICWDSESILLAQSWVPQETVIFAADVRISFDKFRNSMTATVISKTIITTNPDTPEANILLNFIRENKVMNPLDDEIDNYLKESMNLNTIVDVYTVEQLKVKALKNEGKAEPFYGILYAYISTLNIDDETTKVVRNRCSVCGYTVNEASSTCTTCNKDSSGFKSVFLSFDMLIDLTDHTGTLHSCSLTGSVAEETLGCTPGSLCAAPAMLTATVCDKACATTGVNTDTGGSVHSLGAGLSTQGPHADTTPAVPLACFQICQLW", "length": 470, "header": "tr|A0AAA9TCD2-1|G3N1R9_BOVIN Computationally mapped isoform of Meiosis-specific with OB domain-containing protein OS=Bos taurus OX=9913 GN=MEIOB PE=3 SV=1 CANONICAL=G3N1R9-1" }, "locus": { "chromosome": "25", "start_pos": 1435203, "end_pos": 1396041, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000113273.1", "url": "https://www.ensembl.org/id/ENSBTAT00000113273.1" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000094398.1", "url": "https://www.ensembl.org/id/ENSBTAP00000094398.1" } ] } }, { "isoform_ac": "E1BA02-1", "url": "https://www.uniprot.org/uniprotkb/E1BA02/entry", "sequence": { "sequence": "MANSIASKNFTALSNLHPNMANLKIIGIVIGKTDVKGFPDRKNIGSERYTFSFTIRDSTTHFVNATSWGSEDYIRSLSDSFRVGECVIIENPLIQTKDLEREEKFSPATPSNYKLLLSENHSTVKLCSSYEVDAKLLSLIYLPVKESCDYYSLGDIVANGHSLDGKIINVLAAVRSVGEPKYFTTSDRRKGQRCEVKLYDETESSFAMICWDSESILLAQSWVPQETVIFAADVRISFDKFRNSMTATVISKTIITTNPDTPEANILLNFIRENKVMNPLDDEIDNYLKESMNLNTIVDVYTVEQLKVKALKNEGKAEPFYGILYAYISTLNIDDETTKVVRNRCSVCGYTVNEASSTCTTCNKDSSGFKSVFLSFDMLIDLTDHTGTLHSCSLTGSVAEETLGCTFFISHRARGGLRVSVLSCKLADSIEPGSLCAAPAMLTATVCDKACATTGVNTDTGGSVHSLGAGLSTQ", "length": 474, "header": "tr|E1BA02-1|E1BA02_BOVIN Computationally mapped isoform of Meiosis-specific with OB domain-containing protein OS=Bos taurus OX=9913 GN=MEIOB PE=3 SV=3 CANONICAL=G3N1R9-1" }, "locus": { "chromosome": "25", "start_pos": 1435203, "end_pos": 1396104, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000037536.4", "url": "https://www.ensembl.org/id/ENSBTAT00000037536.4" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000037365.4", "url": "https://www.ensembl.org/id/ENSBTAP00000037365.4" } ] } }, { "isoform_ac": "G3N1R9-1", "url": "https://www.uniprot.org/uniprotkb/G3N1R9/entry", "sequence": { "sequence": "MANSIASKNFTALSNLHPNMANLKIIGIVIGKTDVKGFPDRKNIGSERYTFSFTIRDSTTHFVNATSWGSEDYIRSLSDSFRVGECVIIENPLIQTKDLEREEKFSPATPSNYKLLLSENHSTVKLCSSYEVDAKLLSLIYLPVKESCDYYSLGDIVANGHSLDGKIINVLAAVRSVGEPKYFTTSDRRKGQRCEVKLYDETESSFAMICWDSESILLAQSWVPQETVIFAADVRISFDKFRNSMTATVISKTIITTNPDTPEANILLNFIRENKVMNPLDDEIDNYLKESMNLNTIVDVYTVEQLKVKALKNEGKAEPFYGILYAYISTLNIDDETTKVVRNRCSVCGYTVNEASSTCTTCNKDSSGFKSVFLSFDMLIDLTDHTGTLHSCSLTGSVAEETLGCTVDEFLAMTDEQKTALKWQFLLERSKIYLKFFISHRARGGLRVSVLSCKLADSIEASRNLSGQGSVQN", "length": 473, "header": "tr|G3N1R9-1|G3N1R9_BOVIN Isoform 1 of Meiosis-specific with OB domain-containing protein OS=Bos taurus OX=9913 GN=MEIOB PE=3 SV=3 CANONICAL=G3N1R9-1" }, "locus": { "chromosome": "25", "start_pos": 1435203, "end_pos": 1403545, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000065143.3", "url": "https://www.ensembl.org/id/ENSBTAT00000065143.3" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000055822.3", "url": "https://www.ensembl.org/id/ENSBTAP00000055822.3" } ] } } ], "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "other", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 109, "start_aa": "Thr", "end_pos": 109, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr109", "evidence": [ { "id": "", "database": "GlyGen", "url": "https://data.glygen.org/" } ], "filter_code": "000000000000000010000.00000000001000.0.01000" } ], "phosphorylation": [], "glycation": [], "keywords": [ "glycoprotein", "glycoprotein_predicted" ], "publication": [], "pathway": [ { "id": "bta:618487", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?bta:618487", "resource": "KEGG Pathway" } ], "orthologs": [], "go_annotation": { "categories": [ { "name": "Molecular Function", "total": 5, "go_terms": [ { "name": "DNA binding", "id": "GO:0003677", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003677", "evidence": [ { "database": "UniProtKB", "id": "G3N1R9", "url": "https://www.uniprot.org/uniprotkb/G3N1R9" } ], "pmid": "" }, { "name": "exonuclease activity", "id": "GO:0004527", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0004527", "evidence": [ { "database": "UniProtKB", "id": "G3N1R9", "url": "https://www.uniprot.org/uniprotkb/G3N1R9" } ], "pmid": "" }, { "name": "single-stranded DNA 3'-5' DNA exonuclease activity", "id": "GO:0008310", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008310", "evidence": [ { "database": "UniProtKB", "id": "G3N1R9", "url": "https://www.uniprot.org/uniprotkb/G3N1R9" } ], "pmid": "" }, { "name": "chromatin binding", "id": "GO:0003682", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003682", "evidence": [ { "database": "UniProtKB", "id": "G3N1R9", "url": "https://www.uniprot.org/uniprotkb/G3N1R9" } ], "pmid": "" }, { "name": "single-stranded DNA binding", "id": "GO:0003697", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003697", "evidence": [ { "database": "UniProtKB", "id": "G3N1R9", "url": "https://www.uniprot.org/uniprotkb/G3N1R9" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 7, "go_terms": [ { "name": "meiotic cell cycle", "id": "GO:0051321", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0051321", "evidence": [ { "database": "UniProtKB", "id": "G3N1R9", "url": "https://www.uniprot.org/uniprotkb/G3N1R9" } ], "pmid": "" }, { "name": "resolution of meiotic recombination intermediates", "id": "GO:0000712", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000712", "evidence": [ { "database": "UniProtKB", "id": "G3N1R9", "url": "https://www.uniprot.org/uniprotkb/G3N1R9" } ], "pmid": "" }, { "name": "female meiosis I", "id": "GO:0007144", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007144", "evidence": [ { "database": "UniProtKB", "id": "G3N1R9", "url": "https://www.uniprot.org/uniprotkb/G3N1R9" } ], "pmid": "" }, { "name": "fertilization", "id": "GO:0009566", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0009566", "evidence": [ { "database": "UniProtKB", "id": "G3N1R9", "url": "https://www.uniprot.org/uniprotkb/G3N1R9" } ], "pmid": "" }, { "name": "double-strand break repair via homologous recombination", "id": "GO:0000724", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000724", "evidence": [ { "database": "UniProtKB", "id": "G3N1R9", "url": "https://www.uniprot.org/uniprotkb/G3N1R9" } ], "pmid": "" }, { "name": "homologous chromosome pairing at meiosis", "id": "GO:0007129", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007129", "evidence": [ { "database": "UniProtKB", "id": "G3N1R9", "url": "https://www.uniprot.org/uniprotkb/G3N1R9" } ], "pmid": "" }, { "name": "male meiosis I", "id": "GO:0007141", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007141", "evidence": [ { "database": "UniProtKB", "id": "G3N1R9", "url": "https://www.uniprot.org/uniprotkb/G3N1R9" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 3, "go_terms": [ { "name": "nucleus", "id": "GO:0005634", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005634", "evidence": [ { "database": "UniProtKB", "id": "G3N1R9", "url": "https://www.uniprot.org/uniprotkb/G3N1R9" } ], "pmid": "" }, { "name": "cytoplasm", "id": "GO:0005737", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005737", "evidence": [ { "database": "UniProtKB", "id": "G3N1R9", "url": "https://www.uniprot.org/uniprotkb/G3N1R9" } ], "pmid": "" }, { "name": "chromosome", "id": "GO:0005694", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005694", "evidence": [ { "database": "UniProtKB", "id": "G3N1R9", "url": "https://www.uniprot.org/uniprotkb/G3N1R9" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 120, "end_pos": 122, "annotation": "n_glycosylation_sequon" }, { "start_pos": 464, "end_pos": 466, "annotation": "n_glycosylation_sequon" }, { "start_pos": 64, "end_pos": 66, "annotation": "n_glycosylation_sequon" }, { "start_pos": 9, "end_pos": 11, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "G3N1R9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3N1R9" }, { "id": "PF24903", "database": "Pfam", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF24903" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "MEIOB-like N-terminal", "eco_id": "ECO_0000259", "start_pos": 7, "end_pos": 145, "start_aa": "Ser", "end_aa": "Lys", "glycosite_overlap": [] } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [ 109 ], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 120, "end_pos": 122 }, { "start_pos": 464, "end_pos": 466 }, { "start_pos": 64, "end_pos": 66 }, { "start_pos": 9, "end_pos": 11 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 1 }, { "field": "total_sites", "count": 1 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 1 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "exact_sites", "count": 1 }, { "field": "exact_o_linked_sites", "count": 1 }, { "field": "fuzzy_sites", "count": 0 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", 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"uniprot_canonical_ac": "P23356-1", "uniprot_ac": "P23356", "uniprot_id": "UCHL1_BOVIN", "mass": { "chemical_mass": 28335.0, "monoisotopic_mass": 28335.0 }, "refseq": { "ac": "NP_001039637", "name": "ubiquitin carboxyl-terminal hydrolase isozyme L1", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001039637" }, "gene_names": [ { "name": "UCHL1", "type": "recommended", "evidence": [ { "id": "P23356", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P23356" } ] }, { "name": "UCHL1", "type": "synonym", "evidence": [ { "id": "NP_001039637", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001039637" } ] } ], "protein_names": [ { "name": "Ubiquitin carboxyl-terminal hydrolase isozyme L1", "type": "recommended", "evidence": [ { "id": "P23356", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P23356/entry#names_and_taxonomy" } ] }, { "name": "3.4.19.12", "type": "synonym", "evidence": [ { "id": "P23356", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P23356/entry#names_and_taxonomy" } ] }, { "name": "Neuron cytoplasmic protein 9.5", "type": "synonym", "evidence": [ { "id": "P23356", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P23356/entry#names_and_taxonomy" } ] }, { "name": "PGP 9.5", "type": "synonym", "evidence": [ { "id": "NP_001039637", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001039637" }, { "id": "P23356", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P23356/entry#names_and_taxonomy" } ] }, { "name": "PGP9.5", "type": "synonym", "evidence": [ { "id": "NP_001039637", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001039637" }, { "id": "P23356", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P23356/entry#names_and_taxonomy" } ] }, { "name": "UCH-L1", "type": "synonym", "evidence": [ { "id": "NP_001039637", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001039637" }, { "id": "P23356", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P23356/entry#names_and_taxonomy" } ] }, { "name": "Ubiquitin thioesterase L1", "type": "synonym", "evidence": [ { "id": "P23356", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P23356/entry#names_and_taxonomy" } ] }, { "name": "neuron cytoplasmic protein 9.5", "type": "synonym", "evidence": [ { "id": "NP_001039637", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001039637" } ] }, { "name": "ubiquitin carboxyl-terminal esterase L1 (ubiquitin thiolesterase)", "type": "synonym", "evidence": [ { "id": "NP_001039637", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001039637" } ] }, { "name": "ubiquitin carboxyl-terminal hydrolase L1", "type": "synonym", "evidence": [ { "id": "NP_001039637", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001039637" } ] }, { "name": "ubiquitin carboxyl-terminal hydrolase isozyme L1", "type": "synonym", "evidence": [ { "id": "NP_001039637", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001039637" } ] }, { "name": "ubiquitin thioesterase L1", "type": "synonym", "evidence": [ { "id": "NP_001039637", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001039637" } ] } ], "function": [ { "annotation": "These data indicate that antipolyspermy defense in bovine oocytes may rely on UCHL1-controlled functioning of These data indicate that antipolyspermy defense in bovine oocytes may rely on UCHL1-controlled functioning of cortical granules.", "evidence": [ { "database": "RefSeq", "id": "NP_001039637", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001039637" }, { "database": "PubMed", "id": "20164442", "url": "https://glygen.org/publication/PubMed/20164442" } ] }, { "annotation": "Ubiquitin-protein hydrolase involved both in the processing of ubiquitin precursors and of ubiquitinated proteins. This enzyme is a thiol protease that recognizes and hydrolyzes a peptide bond at the C-terminal glycine of ubiquitin. Also binds to free monoubiquitin and may prevent its degradation in lysosomes. The homodimer may have ATP-independent ubiquitin ligase activity.", "evidence": [ { "database": "UniProtKB", "id": "A0A3Q1LTS2", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1LTS2#function" }, { "database": "UniProtKB", "id": "ARBA00054852", "url": "https://www.uniprot.org/uniprotkb/ARBA00054852#function" }, { "database": "UniProtKB", "id": "A0AAF6ZGE9", "url": "https://www.uniprot.org/uniprotkb/A0AAF6ZGE9#function" }, { "database": "UniProtKB", "id": "P23356", "url": "https://www.uniprot.org/uniprotkb/P23356#function" }, { "database": "UniProtKB", "id": "Q9R0P9", "url": "https://www.uniprot.org/uniprotkb/Q9R0P9#function" }, { "database": "UniProtKB", "id": "P09936", "url": "https://www.uniprot.org/uniprotkb/P09936#function" }, { "database": "UniProtKB", "id": "A0A3Q1LK04", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1LK04#function" }, { "database": "UniProtKB", "id": "A0A3Q1M8I6", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1M8I6#function" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Bos taurus", "taxid": 9913, "evidence": [ { "database": "UniProtKB", "id": "P23356", "url": "https://www.uniprot.org/uniprotkb/P23356" } ], "common_name": "Bovine", "glygen_name": "Bovine", "reference_species": "Bos taurus [9913]" } ], "gene": [ { "name": "UCHL1", "url": "https://www.uniprot.org/uniprotkb/P23356", "locus": { "chromosome": "6", "start_pos": 60159346, "end_pos": 60147289, "strand": "-", "evidence": [ { "database": "Ensembl Gene", "id": "ENSBTAG00000005078", "url": "https://www.ensembl.org/id/ENSBTAG00000005078" } ] } } ], "crossref": [ { "id": "P23356", "url": "https://alphafold.ebi.ac.uk/entry/P23356", "database": "AlphaFoldDB", "categories": [] }, { "id": "ENSBTAG00000005078", "url": "https://bgee.org/?page=gene&gene_id=ENSBTAG00000005078", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "cd09616", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd09616", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "514394", "url": "https://www.ncbi.nlm.nih.gov/gene/514394", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR001578", "url": "https://www.ebi.ac.uk/interpro/entry/IPR001578", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR036959", "url": "https://www.ebi.ac.uk/interpro/entry/IPR036959", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR038765", "url": "https://www.ebi.ac.uk/interpro/entry/IPR038765", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR057254", "url": "https://www.ebi.ac.uk/interpro/entry/IPR057254", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "bta:514394", "url": "https://www.genome.jp/dbget-bin/www_bget?bta:514394", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "CISNGEA", "url": "https://omabrowser.org/oma/group/CISNGEA/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "A0A3Q1LK04", "url": "https://www.orthodb.org/?gene=A0A3Q1LK04", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A3Q1LTS2", "url": "https://www.orthodb.org/?gene=A0A3Q1LTS2", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A3Q1M8I6", "url": "https://www.orthodb.org/?gene=A0A3Q1M8I6", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "P23356", "url": "https://www.orthodb.org/?gene=P23356", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR10589", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR10589", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR10589:SF19", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR10589:SF19", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF01088", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF01088", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "R-BTA-5689603", "url": "https://www.reactome.org/PathwayBrowser/#R-BTA-5689603", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "NP_001039637", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001039637", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A3Q1LK04", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1LK04", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A3Q1LK04-1", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1LK04-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A3Q1LTS2", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1LTS2", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A3Q1LTS2-1", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1LTS2-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A3Q1M8I6", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1M8I6", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A3Q1M8I6-1", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1M8I6-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0AAF6ZGE9", "url": "https://www.uniprot.org/uniprotkb/A0AAF6ZGE9", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0AAF6ZGE9-1", "url": "https://www.uniprot.org/uniprotkb/A0AAF6ZGE9-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "P23356", "url": "https://www.uniprot.org/uniprotkb/P23356", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "P23356-1", "url": "https://www.uniprot.org/uniprotkb/P23356-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MQLKPMEINPEMLNKVLTRLGVAGQWRFEDVLGLEEESLGSVPAPACALLLLFPLTAQRCFKLGREAASRFHHPDYPGRLFILLVSQHENFRKKQIEELKGQEVSPKVYFMKQTIGNSCGTIGLIHAVANNQDKLEFEDGSVLKQFLSETEKLSPEDRAKCFEKNEAIQAAHDAVAQEGQCRVDDKVNFHFILFNNVDGHLYELDGRMPFPVNHGTSSEDSLLQDAAKVCREFTEREQGEVRFSAVALCKAA", "length": 252, "header": "sp|P23356-1|UCHL1_BOVIN Isoform 1 of Ubiquitin carboxyl-terminal hydrolase isozyme L1 OS=Bos taurus OX=9913 GN=UCHL1 PE=1 SV=2 CANONICAL=P23356-1" }, "isoforms": [ { "isoform_ac": "A0A3Q1LK04-1", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1LK04/entry", "sequence": { "sequence": "MQETPTNKTHLHNHQIISPASTHNASGRRLIAAAWAAPLAVFSLLWVVFVSTSAKMQLKPMEINPEMLNKVLTRLGVAGQWRFEDVLGLEEESLGSVPAPACALLLLFPLTAQHENFRKKQIEELKGQEVSPKVYFMKQTIGNSCGTIGLIHAVANNQDKLEFEDGSVLKQFLSETEKLSPEDRAKCFEKNEAIQAAHDAVAQEGQCRVDDKVNFHFILFNNVDGHLYELDGRMPFPVNHGTSSEDSLLQDAAKVCREFTEREQGEVRFSAVALCKAA", "length": 278, "header": "tr|A0A3Q1LK04-1|UCHL1_BOVIN Computationally mapped isoform of Ubiquitin carboxyl-terminal hydrolase isozyme L1 OS=Bos taurus OX=9913 GN=UCHL1 PE=1 SV=2 CANONICAL=P23356-1" }, "locus": { "chromosome": "6", "start_pos": 60158939, "end_pos": 60147335, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000072800.3", "url": "https://www.ensembl.org/id/ENSBTAT00000072800.3" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000059848.2", "url": "https://www.ensembl.org/id/ENSBTAP00000059848.2" } ] } }, { "isoform_ac": "A0A3Q1LTS2-1", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1LTS2/entry", "sequence": { "sequence": "MQLKPMEINPEMLNKVLTRLGVAGQWRFEDVLGLEEESLGSVPAPACALLLLFPLTAQHENFRKKQIEELKGQEVSPKVYFMKQTIGNSCGTIGLIHAVANNQDKLEFEDGSVLKQFLSETEKLSPEDRAKCFEKNEVDDKVNFHFILFNNVDGHLYELDGRMPFPVNHGTSSEDSLLQDAAKVCREFTEREQGEVRFSAVALCKAA", "length": 207, "header": "tr|A0A3Q1LTS2-1|A0A3Q1LTS2_BOVIN Computationally mapped isoform of Ubiquitin carboxyl-terminal hydrolase OS=Bos taurus OX=9913 GN=UCHL1 PE=3 SV=2 CANONICAL=P23356-1" }, "locus": { "chromosome": "6", "start_pos": 60158939, "end_pos": 60147625, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000066434.3", "url": "https://www.ensembl.org/id/ENSBTAT00000066434.3" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000063885.2", "url": "https://www.ensembl.org/id/ENSBTAP00000063885.2" } ] } }, { "isoform_ac": "A0A3Q1M8I6-1", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1M8I6/entry", "sequence": { "sequence": "MQLKPMEINPEMLNKVLTRLGVAGQWRFEDVLGLEEESLGSVPAPACALLLLFPLTAQHENFRKKQIEELKGQEVSPKVYFMKQTIGNSCGTIGLIHAVANNQDKLEFEDGSVLKQFLSETEKLSPEDRAKCFEKNEAIQAAHDAVAQEGQCRVDDKVNFHFILFNNVDGHLYELDGRMPFPVNHGTSSEDSLLQDAAKVCREFTEREQGEISTYPQPRPHTGRAQLSMEQV", "length": 232, "header": "tr|A0A3Q1M8I6-1|A0A3Q1M8I6_BOVIN Computationally mapped isoform of Ubiquitin carboxyl-terminal hydrolase OS=Bos taurus OX=9913 GN=UCHL1 PE=3 SV=2 CANONICAL=P23356-1" }, "locus": { "chromosome": "6", "start_pos": 60159129, "end_pos": 60147625, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000072142.2", "url": "https://www.ensembl.org/id/ENSBTAT00000072142.2" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000070222.2", "url": "https://www.ensembl.org/id/ENSBTAP00000070222.2" } ] } }, { "isoform_ac": "A0AAF6ZGE9-1", "url": "https://www.uniprot.org/uniprotkb/A0AAF6ZGE9/entry", "sequence": { "sequence": "MQLKPMEINPEMLNKVLTRLGVAGQWRFEDVLGLEEESLGSVPAPACALLLLFPLTAQRCFKLGREAASRFHHPDYPGRLFILLHENFRKKQIEELKGQEVSPKVYFMKQTIGNSCGTIGLIHAVANNQDKLEFEDGSVLKQFLSETEKLSPEDRAKCFEKNEAIQAAHDAVAQEGQCRVDDKVNFHFILFNNVDGHLYELDGRMPFPVNHGTSSEDSLLQDAAKVCREFTEREQGEVRFSAVALCKAA", "length": 249, "header": "tr|A0AAF6ZGE9-1|A0AAF6ZGE9_BOVIN Computationally mapped isoform of Ubiquitin carboxyl-terminal hydrolase OS=Bos taurus OX=9913 GN=UCHL1 PE=3 SV=1 CANONICAL=P23356-1" }, "locus": { "chromosome": "6", "start_pos": 60158939, "end_pos": 60147625, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000046823.3", "url": "https://www.ensembl.org/id/ENSBTAT00000046823.3" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000044075.2", "url": "https://www.ensembl.org/id/ENSBTAP00000044075.2" } ] } }, { "isoform_ac": "P23356-1", "url": "https://www.uniprot.org/uniprotkb/P23356/entry#P23356-1", "sequence": { "sequence": "MQLKPMEINPEMLNKVLTRLGVAGQWRFEDVLGLEEESLGSVPAPACALLLLFPLTAQRCFKLGREAASRFHHPDYPGRLFILLVSQHENFRKKQIEELKGQEVSPKVYFMKQTIGNSCGTIGLIHAVANNQDKLEFEDGSVLKQFLSETEKLSPEDRAKCFEKNEAIQAAHDAVAQEGQCRVDDKVNFHFILFNNVDGHLYELDGRMPFPVNHGTSSEDSLLQDAAKVCREFTEREQGEVRFSAVALCKAA", "length": 252, "header": "sp|P23356-1|UCHL1_BOVIN Isoform 1 of Ubiquitin carboxyl-terminal hydrolase isozyme L1 OS=Bos taurus OX=9913 GN=UCHL1 PE=1 SV=2 CANONICAL=P23356-1" }, "locus": {} } ], "glycosylation": [], "phosphorylation": [ { "start_pos": 154, "end_pos": 154, "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "residue": "Ser", "comment": "Phosphoserine", "evidence": [ { "database": "UniProtKB", "id": "P23356", "url": "https://www.uniprot.org/uniprotkb/P23356" } ], "site_lbl": "Ser154" } ], "glycation": [], "keywords": [ "enzyme" ], "publication": [ { "title": "'Neuron-specific' protein gene product 9.5 (PGP 9.5) is also expressed in glioma cell lines and its expression depends on cellular growth state.", "journal": "FEBS Lett.", "date": "1991", "authors": "Giambanco I, Bianchi R, Ceccarelli P, Pula G, Sorci G, Antonioli S, Bocchini V, Donato R", "evidence": [ { "database": "UniProtKB", "id": "P23356", "url": "https://www.uniprot.org/uniprotkb/P23356" } ], "reference": [ { "type": "PubMed", "id": "1833240", "url": "https://glygen.org/publication/PubMed/1833240" } ] }, { "title": "Role of ubiquitin C-terminal hydrolase-L1 in antipolyspermy defense of mammalian oocytes.", "journal": "Biology of reproduction", "date": "2010-06", "authors": "Susor Andrej, Liskova Lucie, Toralova Tereza, Pavlok Antonin, Pivonkova Katerina, Karabinova Pavla, Lopatarova Miloslava, Sutovsky Peter, Kubelka Michal", "evidence": [ { "database": "RefSeq", "id": "NP_001039637", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001039637" } ], "reference": [ { "type": "PubMed", "id": "20164442", "url": "https://glygen.org/publication/PubMed/20164442" } ] } ], "pathway": [ { "id": "bta:514394", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?bta:514394", "resource": "KEGG Pathway" }, { "id": "R-BTA-5689603", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-BTA-5689603", "resource": "Reactome", "description": "UCH proteinases" } ], "orthologs": [ { "uniprot_canonical_ac": "A0A8C2MSH8-1", "protein_name": "Ubiquitin carboxyl-terminal hydrolase", "gene_name": "Uchl1", "tax_id": 10029, "organism": "Cricetulus griseus", "sequence": { "sequence": "MQLKPMEINPEMLNKVLAKLGVAGQWRFADVLGLEEEILSTVPTPACALLLLFPLTAQHENFRKKQIEELKGQEVSPKVYFMKQTIGNSCGTIGLIHAVANNQDKLEFEDGSVLKQFLSETEKMSPEDRAKCFEKNEAIQAAHDSVAQEGQCRVDDKVNFHFILFNNVDGHLYELDGRMPFPVNHGASSEDSLLQDAAKVCREFTEREQGEVRFSAVALCKAP", "length": 223 }, "evidence": [ { "id": "P23356", "url": "https://omabrowser.org/oma/group/P23356/", "database": "OMA" } ], "glygen_name": "Hamster", "common_name": "Chinese hamster" }, { "uniprot_canonical_ac": "A0A8V0YUG5-1", "protein_name": "Ubiquitin carboxyl-terminal hydrolase", "gene_name": "UCHL1", "tax_id": 9031, "organism": "Gallus gallus", "sequence": { "sequence": "MAWQPMEINPEMLNKVLSRLGVSPGWRFVDVLGFEEEALGAVPSPACALLLLFPLTEQHENFRKQQTEKIKDQEISSKVYFLKQTVSNSCGTIGLIHAVANNKDKIKLDEGSALKKFLDETADLSPEERAKRFANNKAIQEVHNSVAQEGQCRVEDNSVNFHFILFANVDGHLYELDGRLPFPVNHGTSSDDLLLKDSAKICRQFTEREKGEVRFSAVAFCKSA", "length": 224 }, "evidence": [ { "id": "P23356", "url": "https://omabrowser.org/oma/group/P23356/", "database": "OMA" } ], "glygen_name": "Chicken", "common_name": "Chicken" }, { "uniprot_canonical_ac": "Q00981-1", "protein_name": "Ubiquitin carboxyl-terminal hydrolase isozyme L1", "gene_name": "Uchl1", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MQLKPMEINPEMLNKVLAKLGVAGQWRFADVLGLEEETLGSVPSPACALLLLFPLTAQHENFRKKQIEELKGQEVSPKVYFMKQTIGNSCGTIGLIHAVANNQDKLEFEDGSVLKQFLSETEKLSPEDRAKCFEKNEAIQAAHDSVAQEGQCRVDDKVNFHFILFNNVDGHLYELDGRMPFPVNHGASSEDSLLQDAAKVCREFTEREQGEVRFSAVALCKAA", "length": 223 }, "evidence": [ { "id": "P23356", "url": "https://omabrowser.org/oma/group/P23356/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "Q6SEG5-1", "protein_name": "Ubiquitin carboxyl-terminal hydrolase isozyme L1", "gene_name": "UCHL1", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MQLKPMEINPEMLNKVLTRLGVAGHWRFADVLGLEEESLGSVPAPACALLLLFPLTAQHENFRKKQIEELKGQEVSPKVYFMKQTIGNSCGTIGLIHAVANNQDKLEFEDGSVLKQFLSETEKLSPEDRAKCFEKNEAIQAAHDAVAQEGQCRVDDKVNFHFILFNNVDGHLYELDGRMPFPVNHGASSEDSLLQDAAKVCREFTEREQGEVRFSAVALCKAA", "length": 223 }, "evidence": [ { "id": "P23356", "url": "https://omabrowser.org/oma/group/P23356/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "Q9R0P9-1", "protein_name": "Ubiquitin carboxyl-terminal hydrolase isozyme L1", "gene_name": "Uchl1", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MQLKPMEINPEMLNKVLAKLGVAGQWRFADVLGLEEETLGSVPSPACALLLLFPLTAQHENFRKKQIEELKGQEVSPKVYFMKQTIGNSCGTIGLIHAVANNQDKLEFEDGSVLKQFLSETEKLSPEDRAKCFEKNEAIQAAHDSVAQEGQCRVDDKVNFHFILFNNVDGHLYELDGRMPFPVNHGASSEDSLLQDAAKVCREFTEREQGEVRFSAVALCKAA", "length": 223 }, "evidence": [ { "id": "P23356", "url": "https://omabrowser.org/oma/group/P23356/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" } ], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 8, "go_terms": [ { "name": "cytoplasm", "id": "GO:0005737", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005737", "evidence": [ { "database": "UniProtKB", "id": "P23356", "url": "https://www.uniprot.org/uniprotkb/P23356" } ], "pmid": "" }, { "name": "endoplasmic reticulum membrane", "id": "GO:0005789", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005789", "evidence": [ { "database": "UniProtKB", "id": "P23356", "url": "https://www.uniprot.org/uniprotkb/P23356" } ], "pmid": "" }, { "name": "nucleoplasm", "id": "GO:0005654", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005654", "evidence": [ { "database": "UniProtKB", "id": "P23356", "url": "https://www.uniprot.org/uniprotkb/P23356" } ], "pmid": "" }, { "name": "cytosol", "id": "GO:0005829", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005829", "evidence": [ { "database": "UniProtKB", "id": "P23356", "url": "https://www.uniprot.org/uniprotkb/P23356" } ], "pmid": "" }, { "name": "plasma membrane", "id": "GO:0005886", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005886", "evidence": [ { "database": "UniProtKB", "id": "P23356", "url": "https://www.uniprot.org/uniprotkb/P23356" } ], "pmid": "" }, { "name": "axon", "id": "GO:0030424", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030424", "evidence": [ { "database": "UniProtKB", "id": "P23356", "url": "https://www.uniprot.org/uniprotkb/P23356" } ], "pmid": "" }, { "name": "neuronal cell body", "id": "GO:0043025", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0043025", "evidence": [ { "database": "UniProtKB", "id": "P23356", "url": "https://www.uniprot.org/uniprotkb/P23356" } ], "pmid": "" }, { "name": "neuron projection terminus", "id": "GO:0044306", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0044306", "evidence": [ { "database": "UniProtKB", "id": "P23356", "url": "https://www.uniprot.org/uniprotkb/P23356" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 6, "go_terms": [ { "name": "ubiquitin-dependent protein catabolic process", "id": "GO:0006511", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006511", "evidence": [ { "database": "UniProtKB", "id": "P23356", "url": "https://www.uniprot.org/uniprotkb/P23356" } ], "pmid": "" }, { "name": "protein catabolic process", "id": "GO:0030163", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030163", "evidence": [ { "database": "UniProtKB", "id": "P23356", "url": "https://www.uniprot.org/uniprotkb/P23356" } ], "pmid": "" }, { "name": "protein deubiquitination", "id": "GO:0016579", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016579", "evidence": [ { "database": "UniProtKB", "id": "P23356", "url": "https://www.uniprot.org/uniprotkb/P23356" } ], "pmid": "" }, { "name": "cellular response to xenobiotic stimulus", "id": "GO:0071466", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0071466", "evidence": [ { "database": "UniProtKB", "id": "P23356", "url": "https://www.uniprot.org/uniprotkb/P23356" } ], "pmid": "" }, { "name": "positive regulation of glycolytic process", "id": "GO:0045821", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0045821", "evidence": [ { "database": "UniProtKB", "id": "P23356", "url": "https://www.uniprot.org/uniprotkb/P23356" } ], "pmid": "" }, { "name": "negative regulation of MAPK cascade", "id": "GO:0043409", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0043409", "evidence": [ { "database": "UniProtKB", "id": "P23356", "url": "https://www.uniprot.org/uniprotkb/P23356" } ], "pmid": "" } ] }, { "name": "Molecular Function", "total": 8, "go_terms": [ { "name": "cysteine-type deubiquitinase activity", "id": "GO:0004843", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0004843", "evidence": [ { "database": "UniProtKB", "id": "P23356", "url": "https://www.uniprot.org/uniprotkb/P23356" } ], "pmid": "" }, { "name": "signaling receptor inhibitor activity", "id": "GO:0030547", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030547", "evidence": [ { "database": "UniProtKB", "id": "P23356", "url": "https://www.uniprot.org/uniprotkb/P23356" } ], "pmid": "" }, { "name": "omega peptidase activity", "id": "GO:0008242", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008242", "evidence": [ { "database": "UniProtKB", "id": "P23356", "url": "https://www.uniprot.org/uniprotkb/P23356" } ], "pmid": "" }, { "name": "ubiquitin protein ligase binding", "id": "GO:0031625", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0031625", "evidence": [ { "database": "UniProtKB", "id": "P23356", "url": "https://www.uniprot.org/uniprotkb/P23356" } ], "pmid": "" }, { "name": "alpha-2A adrenergic receptor binding", "id": "GO:0031694", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0031694", "evidence": [ { "database": "UniProtKB", "id": "P23356", "url": "https://www.uniprot.org/uniprotkb/P23356" } ], "pmid": "" }, { "name": "ribosome binding", "id": "GO:0043022", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0043022", "evidence": [ { "database": "UniProtKB", "id": "P23356", "url": "https://www.uniprot.org/uniprotkb/P23356" } ], "pmid": "" }, { "name": "ubiquitin binding", "id": "GO:0043130", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0043130", "evidence": [ { "database": "UniProtKB", "id": "P23356", "url": "https://www.uniprot.org/uniprotkb/P23356" } ], "pmid": "" }, { "name": "cysteine-type endopeptidase activity", "id": "GO:0004197", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0004197", "evidence": [ { "database": "UniProtKB", "id": "P23356", "url": "https://www.uniprot.org/uniprotkb/P23356" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [], "ptm_annotation": [], "interactions": [], "reactions": [ { "id": "R-BTA-5690319", "name": "UCHL1, UCHL3 cleave ubiquitin adducts", "equation": "", "summary": "This event has been computationally inferred from an event that has been demonstrated in another species.

The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.

More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "cellular_location": "cytosol", "input_participant_list": [], "output_participant_list": [ "R-ALL-1131871" ], "enzyme_list": [ "P23356-1", "Q2TBG8-1" ], "evidence": [ { "id": "R-BTA-5690319", "database": "Reactome", "url": "https://www.reactome.org/PathwayBrowser/#R-BTA-5690319" } ] } ], "reaction_participants": [ { "participant_id": "R-ALL-1131871", "participant_name": "L-lysine [cytoplasm]", "crossref": [ { "id": "ZINC000001532522", "database": "ZINC", "url": "" }, { "id": "32551", "database": "ChEBI", "url": "" } ] } ], "reaction_enzymes": [ { "uniprot_ac": "P23356", "gene_name": "UCHL1", "activity": [ { "ec_number": "3.4.19.12", "activity": "Thiol-dependent hydrolysis of ester, thioester, amide, peptide and isopeptide bonds formed by the C-terminal Gly of ubiquitin (a 76-residue protein attached to proteins as an intracellular targeting signal).", "evidence": [ { "id": "P23356", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P23356" } ] }, { "ec_number": "3.4.19.12", "activity": "", "evidence": [ { "id": "P23356", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P23356" } ] } ] }, { "uniprot_ac": "Q2TBG8", "gene_name": "UCHL3", "activity": [ { "ec_number": "3.4.19.12", "activity": "Thiol-dependent hydrolysis of ester, thioester, amide, peptide and isopeptide bonds formed by the C-terminal Gly of ubiquitin (a 76-residue protein attached to proteins as an intracellular targeting signal).", "evidence": [ { "id": "Q2TBG8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q2TBG8" } ] }, { "ec_number": "3.4.19.12", "activity": "", "evidence": [ { "id": "Q2TBG8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q2TBG8" } ] } ] } ], "biomarkers": [], "structures": [ { "pdb_id": "AF-P23356-F1", "pdb_chain": "global", "start_pos": 1, "end_pos": 252, "overlap": "1.0", "method": "AlphaFold", "type": "alphafold", "resolution": -1.0, "url": "https://data.glygen.org/ln2downloads/pdb/current/AF-P23356-F1.pdb", "url_external": "https://alphafold.ebi.ac.uk/entry/P23356" } ], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "P23356", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P23356" }, { "id": "PRU01393", "database": "PROSITE", "url": "https://prosite.expasy.org/PRU01393" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "UCH catalytic", "eco_id": "ECO_0000255", "start_pos": 2, "end_pos": 250, "start_aa": "Gln", "end_aa": "Lys", "glycosite_overlap": [] } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [ { "ec_number": "3.4.19.12", "ec_name": "Thiol-dependent hydrolysis of ester, thioester, amide, peptide and isopeptide bonds formed by the C-terminal Gly of ubiquitin (a 76-residue protein attached to proteins as an intracellular targeting signal).", "evidence": [ { "id": "3.4.19.12", "database": "BRENDA Enzymes", "url": "https://www.brenda-enzymes.org/enzyme.php?ecno=3.4.19.12" } ] } ], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" }, { "name": "homologset.oma", "label": "OMA Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [ 154 ], "sequon_annotation_sites": [] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 1 }, { "field": "total_sites", "count": 1 } ], "sort_fields": [ "start_pos", "end_pos", "kinase_uniprot_canonical_ac", "kinase_gene_name", "residue", "comment", "site_lbl" ] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 2 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ], "tool_support": { "graph_view": "yes" } }, { "uniprot_canonical_ac": "F1N2W9-1", "uniprot_ac": "F1N2W9", "uniprot_id": "MCM9_BOVIN", "mass": { "chemical_mass": 126508.0, "monoisotopic_mass": 126508.0 }, "refseq": { "ac": "XP_002690126", "name": "DNA helicase MCM9 isoform X1", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_002690126" }, "gene_names": [ { "name": "MCM9", "type": "recommended", "evidence": [ { "id": "F1N2W9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1N2W9" } ] }, { "name": "MCM9", "type": "synonym", "evidence": [ { "id": "XP_002690126", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_002690126" } ] } ], "protein_names": [ { "name": "DNA helicase MCM9", "type": "recommended", "evidence": [ { "id": "F1N2W9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1N2W9/entry#names_and_taxonomy" } ] }, { "name": "5.6.2.4", "type": "synonym", "evidence": [ { "id": "F1N2W9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1N2W9/entry#names_and_taxonomy" } ] }, { "name": "DNA 3'-5' helicase MCM9", "type": "synonym", "evidence": [ { "id": "F1N2W9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1N2W9/entry#names_and_taxonomy" } ] }, { "name": "DNA helicase MCM9 isoform X1", "type": "synonym", "evidence": [ { "id": "XP_002690126", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_002690126" } ] }, { "name": "Minichromosome maintenance 9", "type": "synonym", "evidence": [ { "id": "F1N2W9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1N2W9/entry#names_and_taxonomy" } ] } ], "function": [ { "annotation": "Component of the MCM8-MCM9 complex, which is involved in the repair of double-stranded DNA breaks (DBSs) and DNA interstrand cross-links (ICLs) by homologous recombination (HR). The MCM8-MCM9 complex is a 3'-5' DNA helicase and single-stranded (ss)DNA-stimulated ATPase which binds ssDNA in the presence of nucleoside triphosphates. Required for DNA resection by the MRE11-RAD50-NBN/NBS1 (MRN) complex by recruiting the MRN complex to the repair site and by promoting the complex nuclease activity. Indirectly regulates the recruitment of downstream effector RAD51 to DNA damage sites including DBSs and ICLs, probably by regulating the localization of the MNR complex. Acts as a helicase in DNA mismatch repair (MMR) following DNA replication errors to unwind the mismatch containing DNA strand. In addition, recruits MLH1, a component of the MMR complex, to chromatin. The MCM8-MCM9 complex is dispensable for DNA replication and S phase progression. Probably by regulating HR, plays a key role during gametogenesis.", "evidence": [ { "database": "UniProtKB", "id": "F1N2W9", "url": "https://www.uniprot.org/uniprotkb/F1N2W9#function" }, { "database": "UniProtKB", "id": "Q9NXL9", "url": "https://www.uniprot.org/uniprotkb/Q9NXL9#function" }, { "database": "UniProtKB", "id": "Q2KHI9", "url": "https://www.uniprot.org/uniprotkb/Q2KHI9#function" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Bos taurus", "taxid": 9913, "evidence": [ { "database": "UniProtKB", "id": "F1N2W9", "url": "https://www.uniprot.org/uniprotkb/F1N2W9" } ], "common_name": "Bovine", "glygen_name": "Bovine", "reference_species": "Bos taurus [9913]" } ], "gene": [ { "name": "MCM9", "url": "https://www.uniprot.org/uniprotkb/F1N2W9", "locus": { "chromosome": "9", "start_pos": 32210003, "end_pos": 32099900, "strand": "-", "evidence": [ { "database": "Ensembl Gene", "id": "ENSBTAG00000002059", "url": "https://www.ensembl.org/id/ENSBTAG00000002059" } ] } } ], "crossref": [ { "id": "F1N2W9", "url": "https://alphafold.ebi.ac.uk/entry/F1N2W9", "database": "AlphaFoldDB", "categories": [] }, { "id": "ENSBTAG00000002059", "url": "https://bgee.org/?page=gene&gene_id=ENSBTAG00000002059", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "cd17760", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd17760", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "100139498", "url": "https://www.ncbi.nlm.nih.gov/gene/100139498", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR001208", "url": "https://www.ebi.ac.uk/interpro/entry/IPR001208", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR003593", "url": "https://www.ebi.ac.uk/interpro/entry/IPR003593", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR012340", "url": "https://www.ebi.ac.uk/interpro/entry/IPR012340", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR027417", "url": "https://www.ebi.ac.uk/interpro/entry/IPR027417", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR031327", "url": "https://www.ebi.ac.uk/interpro/entry/IPR031327", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR033762", "url": "https://www.ebi.ac.uk/interpro/entry/IPR033762", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR041562", "url": "https://www.ebi.ac.uk/interpro/entry/IPR041562", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR058768", "url": "https://www.ebi.ac.uk/interpro/entry/IPR058768", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "bta:100139498", "url": "https://www.genome.jp/dbget-bin/www_bget?bta:100139498", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "PFQQGVR", "url": "https://omabrowser.org/oma/group/PFQQGVR/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "A0A3Q1MAI1", "url": "https://www.orthodb.org/?gene=A0A3Q1MAI1", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A3Q1N3W3", "url": "https://www.orthodb.org/?gene=A0A3Q1N3W3", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A452DHV4", "url": "https://www.orthodb.org/?gene=A0A452DHV4", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "F1N2W9", "url": "https://www.orthodb.org/?gene=F1N2W9", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR11630", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR11630", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR11630:SF48", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR11630:SF48", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00493", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00493", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF17207", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF17207", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF17855", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF17855", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF26066", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF26066", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "XP_002690126", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_002690126", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "13065", "url": "https://www.rhea-db.org/rhea/13065", "database": "Rhea", "categories": [ "Enzyme and Pathway" ] }, { "id": "A0A3Q1MAI1", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1MAI1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A3Q1MAI1-1", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1MAI1-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A3Q1N3W3", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1N3W3", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A3Q1N3W3-1", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1N3W3-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A452DHV4", "url": "https://www.uniprot.org/uniprotkb/A0A452DHV4", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A452DHV4-1", "url": "https://www.uniprot.org/uniprotkb/A0A452DHV4-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "F1N2W9", "url": "https://www.uniprot.org/uniprotkb/F1N2W9", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "F1N2W9-1", "url": "https://www.uniprot.org/uniprotkb/F1N2W9-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MNSDQVTLVGQVFESYVSEYHKNDILLILKERDEDAHYPVVVNAMTLFETNMEIGEYFNAFPNEVLTIFDNALRRSALTILQSLSQPEGLSMKQNLHARISGLPVCPELVREHIPKTKDVGHFLSVTGTVIRTSLVKILEFERDYMCNKCKHVFVVQADFEQYYTFFRPSSCPSLENCDSSKFTCLSDLSSPTRCRDYQEIKIQEQVQRLSVGSIPRSMQVILEDDLVDSCKSGDDITIYGVVMQRWKPFKQDVRCEVEIVLKANYIQVNNEESAGVNMDEEVRKEFEDFWEHYKSDPFAGRNEILASLCPQVFGMYLVKLAVAMVLAGGIQRTDATGTRVRGESHLLLVGDPGTGKSQFLKYAAKITPRSVLTTGIGSTSAGLTVTAVKDSGEWNLEAGALVLADAGLCCIDEFNSLKEHDRTSIHEAMEQQTISVAKAGLVCKLNTRTTILAATNPKGQYDPRESVSVNIALSSPLLSRFDLILVLLDTKNEDWDRIISSFILENKGYPSKSEKLWSMEKMKSYFCLIRKLQPTLSDEGNQVLLRYYQMQRQSDSRNAARTTIRLLESLIRLAEAHARLMFRDTVTLEDAVTVVSVMESSMQGGALLGGVNALHTSFPENPLQQYQTQCELILEKLELPNLLSEELRRLERLQNWSVDQSQPQAMEAETIPGSLGGDARKESNFRTSTQQEVNCSAHRFSIGGSFGGSPLLGPSSHLGPKGPASGKHSEEHRNSQDGSLDWFDSVATHPIEPKNTAPVSPSPKTSRGAMALKICNNRSQGKEDREAGQRSKLETEPLPAAGETETPLRPGNREGERPRKAATVSEAAVSADEPDSVLTHHVPRKLHKLHKARAQELCRNPTRPPLQPTSPSHPQPTPIQSPERVLETPKRKRQKSHAQAQEPHQESVESLGAPVAKLAKFTFKQKSKLTHSPEDRGPVSPGTSKPVVQSPENPQRRAKRGAALPGKGPEKLASRIRSSAQPQDETRGVSPQPPYKDRPEEKRERAPAKGTVQPELELGNDMGRFFLASERVRKEEVSCSNKSSKVHACTLAKLANFSFTSPSESKSESPPPPQSKNPSEGGPSCVATATALGRKRKTFQLDTSTEKLSLSKTSLFTLPELDDEPLDFDWDEEMRKKP", "length": 1139, "header": "sp|F1N2W9-1|MCM9_BOVIN Isoform 1 of DNA helicase MCM9 OS=Bos taurus OX=9913 GN=MCM9 PE=3 SV=2 CANONICAL=F1N2W9-1" }, "isoforms": [ { "isoform_ac": "A0A3Q1MAI1-1", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1MAI1/entry", "sequence": { "sequence": "MNSDQVTLVGQVFESYVSEYHKNDILLILKERDEDAHYPVVVNAMTLFETNMEIGEYFNAFPNEVLTIFDNALRRSALTILQSLSQPEGLSMKQNLHARISGLPVCPELVREHIPKTKDVGHFLSVTGTVIRTSLVKILEFERDYMCNKCKHVFVVQADFEQYYTFFRPSSCPSLENCDSSKFTCLSDLSSPTRCRDYQEIKIQEQVQRLSVGSIPRSMQVILEDDLVDSCKSGDDITIYGVVMQRWKPFKQDVRCEVEIVLKANYIQVNNEESAGVNMDEEVRKEFEDFWEHYKSDPFAGRNEILASLCPQVFGMYLVKLAVAMVLAGGIQRTDATGTRVRGESHLLLVGDPGTGKSQFLKYAAKITPRSVLTTGIGSTSAGLTVTAVKDSGEWNLEAGALVLADAGLCCIDEFNSLKEHDRTSIHEAMEQQTISVAKAGLVCKLNTRTTILAATNPKGQYDPRESVSVNIALSSPLLSRFDLILVLLDTKNEDWDRIISSFILENKGYPSKSEKLWSMEKMKSYFCLIRKLQPTLSDEGNQVLLRYYQMQRQSDSRNAARTTIRLLESLIRLAEAHARLMFRDTVTLEDAVTVVSVMESSMQGGALLGGVNALHTSFPENPLQQYQTQCELILEKLELPNLLSEELRRLERLQNWSVDQSQPQAMEAETIPGSLGGDARKESNFRTSTQQEVNCSAHRFSIGGSFGGSPLLGPSSHLGPKGPASGKHSEEHRNSQDGSLDWFDSVATHPIEPKNTAPVSPSPKTSRGAMALKICNNRSQGKEDREAGQRSKLETEPLPAAGETETPLRPGNREGERPRKAATVSEAAVSADEPDSVLTHHVPRKLHKLHKARAQELCRNPTRPPLQPTSPSHPQPTPIQSPERVLETPKRKRQKSHAQAQEPHQESVESLGAPVAKLAKFTFKQKSKLTHSPEDRGPVSPGTSKPVVQSPENPQRRAKRGAALPGKGPEKLASRIRSSAQPQDETRGVSPQPPYKDRPEEKRERAPAKGTVQPELELGANLREGKSRVESRGERPSWLRVPPPWPSLSPVFRLIIALCFTPSLFKRPRLHGLNRMRTAERNI", "length": 1084, "header": "tr|A0A3Q1MAI1-1|A0A3Q1MAI1_BOVIN Computationally mapped isoform of DNA helicase MCM9 OS=Bos taurus OX=9913 GN=MCM9 PE=3 SV=2 CANONICAL=F1N2W9-1" }, "locus": { "chromosome": "9", "start_pos": 32209186, "end_pos": 32102923, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000076724.3", "url": "https://www.ensembl.org/id/ENSBTAT00000076724.3" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000071025.2", "url": "https://www.ensembl.org/id/ENSBTAP00000071025.2" } ] } }, { "isoform_ac": "A0A3Q1N3W3-1", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1N3W3/entry", "sequence": { "sequence": "MNSDQVTLVGQVFESYVSEYHKNDILLILKERDEDAHYPVVVNAMTLFETNMEIGEYFNAFPNEVLTIFDNALRRSALTILQSLSQPEGLSMKQNLHARISGLPVCPELVREHIPKTKDVGHFLSVTGTVIRTSLVKILEFERDYMCNKCKHVFVVQADFEQYYTFFRPSSCPSLENCDSSKFTCLSDLSSPTRCRDYQEIKIQEQVQRLSVGSIPRSMQVILEDDLVDSCKSGDDITIYGVVMQRWKPFKQDVRCEVEIVLKANYIQVNNEESAGVNMDEEVRKEFEDFWEHYKSDPFAGRNEILASLCPQVFGMYLVKLAVAMVLAGGIQRTDATGTRVRGESHLLLVGDPGTGKSQFLKYAAKITPRSVLTTGIGSTSAGLTVTAVKDSGEWNLEAGALVLADAGLCCIDEFNSLKEHDRTSIHEAMEQQTISVAKAGLVCKLNTRTTILAATNPKGQYDPRESVSVNIALSSPLLSRFDLILVLLDTKNEDWDRIISSFILENKGYPSKSEKLWSMEKMKSYFCLIRKLQPTLSDEGNQVLLRYYQMQRQSDSRNAARTTIRLLESLIRLAEAHARLMFRDTVTLEDAVTVVSVMESSMQGGALLGGVNALHTSFPENPLQQYQTQCELILEKLELPNLLSEELRRLERLQNWSVDQSQPQAMEAETIPGSLGGDARKESNFRTSTQQEVNCSAHRFSIGGSFGGSPLLGPSSHLGPKGPASGKHSEEHRNSQDGSLDWFDSVATHPIEPKNTAPVSPSPKTSRGAMALKICNNRSQGKEDREAGQRSKLETEPLPAAGETETPLRPGNREGERPRKAATVSEAAVSADEPDSVLTHHVPRKLHKLHKARAQELCRNPTRPPLQPTSPSHPQPTPIQSPERVLETPKRKRQKSHAQAQEPHQESVESLGAPVAKLAKFTFKQKSKLTHSPEDRGPVSPGTSKPVVQSPENPQRRAKRGAALPGKGPEKLASRIRSSAQPQDETRGVSPQPPYKDRPEEKRERAPAKGTVQPELELGANLREGKSRVESRGERPTGLQPSLK", "length": 1045, "header": "tr|A0A3Q1N3W3-1|MCM9_BOVIN Computationally mapped isoform of DNA helicase MCM9 OS=Bos taurus OX=9913 GN=MCM9 PE=3 SV=2 CANONICAL=F1N2W9-1" }, "locus": { "chromosome": "9", "start_pos": 32209890, "end_pos": 32102923, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000068420.3", "url": "https://www.ensembl.org/id/ENSBTAT00000068420.3" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000064308.2", "url": "https://www.ensembl.org/id/ENSBTAP00000064308.2" } ] } }, { "isoform_ac": "A0A452DHV4-1", "url": "https://www.uniprot.org/uniprotkb/A0A452DHV4/entry", "sequence": { "sequence": "MNSDQVTLVGQVFESYVSEYHKNDILLILKERDEDAHYPVVVNAMTLFETNMEIGEYFNAFPNEVLTIFDNALRRSALTILQSLSQPEGLSMKQNLHARISGLPVCPELVREHIPKTKDVGHFLSVTGTVIRTSLVKILEFERDYMCNKCKHVFVVQADFEQYYTFFRPSSCPSLENCDSSKFTCLSDLSSPTRCRDYQEIKIQEQVQRLSVGSIPRSMQVILEDDLVDSCKSGDDITIYGVVMQRWKPFKQDVRCEVEIVLKANYIQVNNEESAGVNMDEEVRKEFEDFWEHYKSDPFAGRNEILASLCPQVFGMYLVKLAVAMVLAGGIQRTDATGTRVRGESHLLLVGDPGTGKSQFLKYAAKITPRSVLTTGIGSTSAGLTVTAVKDSGEWNLEAGALVLADAGLCCIDEFNSLKEHDRTSIHEAMEQQTISVAKAGLVCKLNTRTTILAATNPKGQYDPRESVSVNIALSSPLLSRFDLILVLLDTKNEDWDRIISSFILENKGYPSKSEKLWSMEKMKSYFCLIRKLQPTLSDEGNQVLLRYYQMQRQSDSRNAARTTIRLLESLIRLAEAHARLMFRDTVTLEDAVTVVSVMESSMQGGALLGGVNALHTSFPENPLQQYQTQCELILEKLELPNLLSEELRRLERLQNWSVDQSQPQAMEAETIPGSLGGDARKESNFRTSTQQEVNCSAHRFSIGGSFGGSPLLGPSSHLGPKGPASGKHSEEHRNSQDGSLDWFDSVATHPIEPKNTAPVSPSPKTSRGAMALKICNNRSQGKEDREAGQRSKLETEPLPAAGETETPLRPGNREGERPRKAATVSEAAVSADEPDSVLTHHVPRKLHKLHKARAQELCRNPTRPPLQPTSPSHPQPTPIQSPERVLETPKRKRQKSHAQAQEPHQESVESLGAPVAKLAKFTFKQKSKLTHSPEDRGPVSPGTSKPVVQSPENPQRRAKRGAALPGKGPEKLASRIRSSAQPQDETRGVSPQPPYKDRPEEKRERAPAKGTVQPELELGNDMGHFFLASERVRKEEVSCSNKSSKVHACTLAKLANFSFTSPSESKSESPPPPQSKNPSEGGPSCVATATALGRKRKTFQLDTSTEKLSLSKTSLFTLPELDDEPLDFDWDEEMRKKP", "length": 1139, "header": "tr|A0A452DHV4-1|MCM9_BOVIN Computationally mapped isoform of DNA helicase MCM9 OS=Bos taurus OX=9913 GN=MCM9 PE=3 SV=1 CANONICAL=F1N2W9-1" }, "locus": { "chromosome": "9", "start_pos": 32194278, "end_pos": 32102923, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000002665.8", "url": "https://www.ensembl.org/id/ENSBTAT00000002665.8" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000002665.6", "url": "https://www.ensembl.org/id/ENSBTAP00000002665.6" } ] } }, { "isoform_ac": "F1N2W9-1", "url": "https://www.uniprot.org/uniprotkb/F1N2W9/entry#F1N2W9-1", "sequence": { "sequence": "MNSDQVTLVGQVFESYVSEYHKNDILLILKERDEDAHYPVVVNAMTLFETNMEIGEYFNAFPNEVLTIFDNALRRSALTILQSLSQPEGLSMKQNLHARISGLPVCPELVREHIPKTKDVGHFLSVTGTVIRTSLVKILEFERDYMCNKCKHVFVVQADFEQYYTFFRPSSCPSLENCDSSKFTCLSDLSSPTRCRDYQEIKIQEQVQRLSVGSIPRSMQVILEDDLVDSCKSGDDITIYGVVMQRWKPFKQDVRCEVEIVLKANYIQVNNEESAGVNMDEEVRKEFEDFWEHYKSDPFAGRNEILASLCPQVFGMYLVKLAVAMVLAGGIQRTDATGTRVRGESHLLLVGDPGTGKSQFLKYAAKITPRSVLTTGIGSTSAGLTVTAVKDSGEWNLEAGALVLADAGLCCIDEFNSLKEHDRTSIHEAMEQQTISVAKAGLVCKLNTRTTILAATNPKGQYDPRESVSVNIALSSPLLSRFDLILVLLDTKNEDWDRIISSFILENKGYPSKSEKLWSMEKMKSYFCLIRKLQPTLSDEGNQVLLRYYQMQRQSDSRNAARTTIRLLESLIRLAEAHARLMFRDTVTLEDAVTVVSVMESSMQGGALLGGVNALHTSFPENPLQQYQTQCELILEKLELPNLLSEELRRLERLQNWSVDQSQPQAMEAETIPGSLGGDARKESNFRTSTQQEVNCSAHRFSIGGSFGGSPLLGPSSHLGPKGPASGKHSEEHRNSQDGSLDWFDSVATHPIEPKNTAPVSPSPKTSRGAMALKICNNRSQGKEDREAGQRSKLETEPLPAAGETETPLRPGNREGERPRKAATVSEAAVSADEPDSVLTHHVPRKLHKLHKARAQELCRNPTRPPLQPTSPSHPQPTPIQSPERVLETPKRKRQKSHAQAQEPHQESVESLGAPVAKLAKFTFKQKSKLTHSPEDRGPVSPGTSKPVVQSPENPQRRAKRGAALPGKGPEKLASRIRSSAQPQDETRGVSPQPPYKDRPEEKRERAPAKGTVQPELELGNDMGRFFLASERVRKEEVSCSNKSSKVHACTLAKLANFSFTSPSESKSESPPPPQSKNPSEGGPSCVATATALGRKRKTFQLDTSTEKLSLSKTSLFTLPELDDEPLDFDWDEEMRKKP", "length": 1139, "header": "sp|F1N2W9-1|MCM9_BOVIN Isoform 1 of DNA helicase MCM9 OS=Bos taurus OX=9913 GN=MCM9 PE=3 SV=2 CANONICAL=F1N2W9-1" }, "locus": {} } ], "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "other", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 878, "start_aa": "Thr", "end_pos": 878, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr878", "evidence": [ { "id": "", "database": "GlyGen", "url": "https://data.glygen.org/" } ], "filter_code": "000000000000000010000.00000000001000.0.01000" } ], "phosphorylation": [ { "start_pos": 1105, "end_pos": 1105, "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "residue": "Ser", "comment": "Phosphoserine", "evidence": [ { "database": "UniProtKB", "id": "F1N2W9", "url": "https://www.uniprot.org/uniprotkb/F1N2W9" } ], "site_lbl": "Ser1105" }, { "start_pos": 761, "end_pos": 761, "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "residue": "Ser", "comment": "Phosphoserine", "evidence": [ { "database": "UniProtKB", "id": "F1N2W9", "url": "https://www.uniprot.org/uniprotkb/F1N2W9" } ], "site_lbl": "Ser761" } ], "glycation": [], "keywords": [ "enzyme", "glycoprotein", "glycoprotein_predicted" ], "publication": [ { "title": "A whole-genome assembly of the domestic cow, Bos taurus.", "journal": "Genome Biol.", "date": "2009", "authors": "Zimin Aleksey V, Delcher Arthur L, Florea Liliana, Kelley David R, Schatz Michael C, Puiu Daniela, Hanrahan Finnian, Pertea Geo, Van Tassell Curtis P, Sonstegard Tad S, Mar\u00e7ais Guillaume, Roberts Michael, Subramanian Poorani, Yorke James A, Salzberg Steven L", "evidence": [ { "database": "UniProtKB", "id": "F1N2W9", "url": "https://www.uniprot.org/uniprotkb/F1N2W9" } ], "reference": [ { "type": "PubMed", "id": "19393038", "url": "https://glygen.org/publication/PubMed/19393038" } ] } ], "pathway": [ { "id": "bta:100139498", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?bta:100139498", "resource": "KEGG Pathway" } ], "orthologs": [ { "uniprot_canonical_ac": "A0A9J7FJ37-1", "protein_name": "DNA helicase MCM9", "gene_name": "Mcm9", "tax_id": 10029, "organism": "Cricetulus griseus", "sequence": { "sequence": "MNSDQVALVGQVFESYVSEYHKNDILLILKERDEDAHYPVVVNAMTLFETNMEIGEYFTVFPNEVLTVFDSALRRSALTILQSLPEPEGFSMKQNLHARISGLPVCPELVREHIPKTKDVGHFLSVTGTVIRTSLVKVLEYERDYMCNKCKHVFVVQADFEQYYTFCRPSSCPSLESCDSSKFTCLSDMSSSPARCRDYQEIKIQEQVQRLAVGSIPRSMKVILEDDLVDSCKSGDDLTIYGVVMQRWKPFQRDARCEVEIVLKSNYVQVNNEQSSGMVMDEEVRKEFEDFWEHYKSDPFAGRNEILASLCPQVFGMYLVKLAVAMVLAGGIQRTDSAGTRVRGESHLLLVGDPGTGKSQFLKYAAKITPRSVLTTGIGSTSAGLTVTAVKDSGEWNLEAGALVLADAGLCCIDEFNSLKEHDRTSIHEAMEQQTISVAKAGLVCKLNTRTTILAATNPKGQYDPQESVSVNIALGSPLLSRFDLVLVLLDTRNEDWDRIISSFILENKGYPSKSENLWSMEKMKTYFCLIRNLQPTLSDVSNQVLLRYYQMQRQSDSRNAARTTIRLLESLIRLAEAHARLMFRNTVTLEDAITVVSVMESSMQGGALLGGVNALHTSFPESPRAQYRRQCELILEKLELQSLLSEELRRLERLQNENVHQPQPQAVNVESAPGSSRNDPRDKPRLRTSTQQEQSFSCYNSSPAGSSTECPDGDSTSGLGLNGPTSSNHSAEHKGCRDDTLDSFTLVATPEIESESSAVSPELKTTEENVALKIPNNKPQGKEKHGSGHRSKLLETGHLPSLGAMDAPLRSHGVRGTKARKAVVVSEGAGQDNKPDSGLNHIPHRSPKLLKEGSQSMHSSTTRVRSLPFTPSIPLPGPEKTTGIPKRKRQKSPAQVGEPEPESVETTHTPLVKLAKFTFKQKTKLSHSSDGHSPVPPSSPKIAVSSSKIPQQRTRREATVPVKGRRKLTSTSGDGCSDQLQGNTKELSRQLPERSQPQEERDQGPERRVIQLELELGNQAGHSHPACETDKKEGGSCSNKSSKVHSGTLARLATFSFASPPESKSESLPPERKDHGERRHSPPAATVPGLGQQRQSFQLQPSTERGNLSTHSLFTLSELDDEALDFDWDEEMSKKS", "length": 1137 }, "evidence": [ { "id": "F1N2W9", "url": "https://omabrowser.org/oma/group/F1N2W9/", "database": "OMA" } ], "glygen_name": "Hamster", "common_name": "Chinese hamster" }, { "uniprot_canonical_ac": "F1M5F3-1", "protein_name": "DNA helicase MCM9", "gene_name": "Mcm9", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MNSEQVTLVGQVFESYVSEYHKNDILLILKERDEDAHYPLVVNAMTLFETNMEIGDYFTVFPNEVLTVFDSALRRSALAVLQSLPEPEGLSMKQNLHARISGLPVCPELVREHIPKTKDVGHFLSVTGTVIRTSLVKVLEFERDYMCNKCKYVFTVKADFEQYYTFSRPSSCPSSDTCDSSKFTCLSDLSASPARCRDYQEIKIQEQVQRLSVGSIPRSMKVILEDDLVDSCKSGDDLTIYGVVMQRWKPFQRDMRCEVEIVLKANYVQVNNEQSSGMVMDEDARKEFEDFWEHYKSDPFAGRNEILASLCPQVFGMYLVKLAVAMVLAGGIQRTDAAGTRVRGESHLLLVGDPGTGKSQFLKYAAKITPRSVLTTGIGSTSAGLTVTAVKDSGEWNLEAGALVLADAGLCCIDEFNSLKEHDRTSIHEAMEQQTISVAKAGLVCKLNTRTTILAATNPKGQYDPQESVSVNIALGSPLLSRFDLILVLLDTRNEDWDRIISSFILENKGYPSKSENLWSMEKMKTYFCLIRNLHPTLSDVSNQVLLRYYQMQRQSDSRNAARTTIRLLESLIRLAEAHARLMFRSTVTLEDAITVVSVMESSMQGGALLGGVNALHTSFPESPRAQYRRQCELILEKLELQSLLQEELRRLERLQNESDQCQPHSPEVEAAPGSCRNDPRDRPGLRTPTQQEQSCSWSPAESSGGDSPTGPGLSRPTSCNHKAEDGGGRGDCLAWADPTASPEIAQESTIVSPGLKTMEEKEDLKISNNGAQGKGKHGLQKRSQLLKPGRLPASGATDTSLRSRGSESTRARQAAVVSEAGRDDDQESGPRRLPRLLKEGSQSVCTTRVRTLPPTVPFPLSISPPGPGKKTGTPKRKRQKSAQVEAPGPEGTETMSAPVVKLAKFTFKQKSKLTHSPEGQGPMPPSASKVAVDSSKIPRQRTRREAGVPAAGPGQSTSTSGDRCSEQLQGQTKALSRQPPESHRPREEKEQGPERRVIQSELELGSQAGHSHPACKKDRKEGASCSNKSKVHAGTMARLANFSFTSPPESKSESLPPERKESRDRSHNPPATTAPVLGQQRQSFQLQQPPERVNLSTLSLFTLSELDDEALDFDWDEEMRKKP", "length": 1124 }, "evidence": [ { "id": "F1N2W9", "url": "https://omabrowser.org/oma/group/F1N2W9/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "Q9NXL9-1", "protein_name": "DNA helicase MCM9", "gene_name": "MCM9", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MNSDQVTLVGQVFESYVSEYHKNDILLILKERDEDAHYPVVVNAMTLFETNMEIGEYFNMFPSEVLTIFDSALRRSALTILQSLSQPEAVSMKQNLHARISGLPVCPELVREHIPKTKDVGHFLSVTGTVIRTSLVKVLEFERDYMCNKCKHVFVIKADFEQYYTFCRPSSCPSLESCDSSKFTCLSGLSSSPTRCRDYQEIKIQEQVQRLSVGSIPRSMKVILEDDLVDSCKSGDDLTIYGIVMQRWKPFQQDVRCEVEIVLKANYIQVNNEQSSGIIMDEEVQKEFEDFWEYYKSDPFAGRNVILASLCPQVFGMYLVKLAVAMVLAGGIQRTDATGTRVRGESHLLLVGDPGTGKSQFLKYAAKITPRSVLTTGIGSTSAGLTVTAVKDSGEWNLEAGALVLADAGLCCIDEFNSLKEHDRTSIHEAMEQQTISVAKAGLVCKLNTRTTILAATNPKGQYDPQESVSVNIALGSPLLSRFDLILVLLDTKNEDWDRIISSFILENKGYPSKSEKLWSMEKMKTYFCLIRNLQPTLSDVGNQVLLRYYQMQRQSDCRNAARTTIRLLESLIRLAEAHARLMFRDTVTLEDAITVVSVMESSMQGGALLGGVNALHTSFPENPGEQYQRQCELILEKLELQSLLSEELRRLERLQNQSVHQSQPRVLEVETTPGSLRNGPGEESNFRTSSQQEINYSTHIFSPGGSPEGSPVLDPPPHLEPNRSTSRKHSAQHKNNRDDSLDWFDFMATHQSEPKNTVVVSPHPKTSGENMASKISNSTSQGKEKSEPGQRSKVDIGLLPSPGETGVPWRADNVESNKKKRLALDSEAAVSADKPDSVLTHHVPRNLQKLCKERAQKLCRNSTRVPAQCTVPSHPQSTPVHSPDRMLDSPKRKRPKSLAQVEEPAIENVKPPGSPVAKLAKFTFKQKSKLIHSFEDHSHVSPGATKIAVHSPKISQRRTRRDAALPVKRPGKLTSTPGNQISSQPQGETKEVSQQPPEKHGPREKVMCAPEKRIIQPELELGNETGCAHLTCEGDKKEEVSGSNKSGKVHACTLARLANFCFTPPSESKSKSPPPERKNRGERGPSSPPTTTAPMRVSKRKSFQLRGSTEKLIVSKESLFTLPELGDEAFDCDWDEEMRKKS", "length": 1143 }, "evidence": [ { "id": "F1N2W9", "url": "https://omabrowser.org/oma/group/F1N2W9/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" } ], "go_annotation": { "categories": [ { "name": "Molecular Function", "total": 13, "go_terms": [ { "name": "3'-5' DNA helicase activity", "id": "GO:0043138", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0043138", "evidence": [ { "database": "UniProtKB", "id": "F1N2W9", "url": "https://www.uniprot.org/uniprotkb/F1N2W9" } ], "pmid": "" }, { "name": "ATP binding", "id": "GO:0005524", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005524", "evidence": [ { "database": "UniProtKB", "id": "F1N2W9", "url": "https://www.uniprot.org/uniprotkb/F1N2W9" } ], "pmid": "" }, { "name": "metal ion binding", "id": "GO:0046872", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0046872", "evidence": [ { "database": "UniProtKB", "id": "F1N2W9", "url": "https://www.uniprot.org/uniprotkb/F1N2W9" } ], "pmid": "" }, { "name": "ATP hydrolysis activity", "id": "GO:0016887", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016887", "evidence": [ { "database": "UniProtKB", "id": "F1N2W9", "url": "https://www.uniprot.org/uniprotkb/F1N2W9" } ], "pmid": "" }, { "name": "single-stranded DNA binding", "id": "GO:0003697", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003697", "evidence": [ { "database": "UniProtKB", "id": "F1N2W9", "url": "https://www.uniprot.org/uniprotkb/F1N2W9" } ], "pmid": "" }, { "name": "DNA binding", "id": "GO:0003677", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003677", "evidence": [ { "database": "UniProtKB", "id": "F1N2W9", "url": "https://www.uniprot.org/uniprotkb/F1N2W9" } ], "pmid": "" }, { "name": "hydrolase activity", "id": "GO:0016787", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016787", "evidence": [ { "database": "UniProtKB", "id": "F1N2W9", "url": "https://www.uniprot.org/uniprotkb/F1N2W9" } ], "pmid": "" }, { "name": "DNA helicase activity", "id": "GO:0003678", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003678", "evidence": [ { "database": "UniProtKB", "id": "F1N2W9", "url": "https://www.uniprot.org/uniprotkb/F1N2W9" } ], "pmid": "" }, { "name": "chromatin binding", "id": "GO:0003682", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003682", "evidence": [ { "database": "UniProtKB", "id": "F1N2W9", "url": "https://www.uniprot.org/uniprotkb/F1N2W9" } ], "pmid": "" }, { "name": "enzyme binding", "id": "GO:0019899", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0019899", "evidence": [ { "database": "UniProtKB", "id": "F1N2W9", "url": "https://www.uniprot.org/uniprotkb/F1N2W9" } ], "pmid": "" }, { "name": "MutSalpha complex binding", "id": "GO:0032407", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0032407", "evidence": [ { "database": "UniProtKB", "id": "F1N2W9", "url": "https://www.uniprot.org/uniprotkb/F1N2W9" } ], "pmid": "" }, { "name": "MutLbeta complex binding", "id": "GO:0032406", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0032406", "evidence": [ { "database": "UniProtKB", "id": "F1N2W9", "url": "https://www.uniprot.org/uniprotkb/F1N2W9" } ], "pmid": "" }, { "name": "MutSbeta complex binding", "id": "GO:0032408", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0032408", "evidence": [ { "database": "UniProtKB", "id": "F1N2W9", "url": "https://www.uniprot.org/uniprotkb/F1N2W9" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 4, "go_terms": [ { "name": "nucleus", "id": "GO:0005634", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005634", "evidence": [ { "database": "UniProtKB", "id": "F1N2W9", "url": "https://www.uniprot.org/uniprotkb/F1N2W9" } ], "pmid": "" }, { "name": "chromosome", "id": "GO:0005694", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005694", "evidence": [ { "database": "UniProtKB", "id": "F1N2W9", "url": "https://www.uniprot.org/uniprotkb/F1N2W9" } ], "pmid": "" }, { "name": "MCM8-MCM9 complex", "id": "GO:0097362", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0097362", "evidence": [ { "database": "UniProtKB", "id": "F1N2W9", "url": "https://www.uniprot.org/uniprotkb/F1N2W9" } ], "pmid": "" }, { "name": "MCM complex", "id": "GO:0042555", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0042555", "evidence": [ { "database": "UniProtKB", "id": "F1N2W9", "url": "https://www.uniprot.org/uniprotkb/F1N2W9" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 7, "go_terms": [ { "name": "DNA damage response", "id": "GO:0006974", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006974", "evidence": [ { "database": "UniProtKB", "id": "F1N2W9", "url": "https://www.uniprot.org/uniprotkb/F1N2W9" } ], "pmid": "" }, { "name": "double-strand break repair via homologous recombination", "id": "GO:0000724", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000724", "evidence": [ { "database": "UniProtKB", "id": "F1N2W9", "url": "https://www.uniprot.org/uniprotkb/F1N2W9" } ], "pmid": "" }, { "name": "female gamete generation", "id": "GO:0007292", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007292", "evidence": [ { "database": "UniProtKB", "id": "F1N2W9", "url": "https://www.uniprot.org/uniprotkb/F1N2W9" } ], "pmid": "" }, { "name": "gamete generation", "id": "GO:0007276", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007276", "evidence": [ { "database": "UniProtKB", "id": "F1N2W9", "url": "https://www.uniprot.org/uniprotkb/F1N2W9" } ], "pmid": "" }, { "name": "recombinational interstrand cross-link repair", "id": "GO:0036298", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0036298", "evidence": [ { "database": "UniProtKB", "id": "F1N2W9", "url": "https://www.uniprot.org/uniprotkb/F1N2W9" } ], "pmid": "" }, { "name": "mismatch repair involved in maintenance of fidelity involved in DNA-dependent DNA replication", "id": "GO:0070716", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0070716", "evidence": [ { "database": "UniProtKB", "id": "F1N2W9", "url": "https://www.uniprot.org/uniprotkb/F1N2W9" } ], "pmid": "" }, { "name": "protein localization to chromatin", "id": "GO:0071168", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0071168", "evidence": [ { "database": "UniProtKB", "id": "F1N2W9", "url": "https://www.uniprot.org/uniprotkb/F1N2W9" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 1042, "end_pos": 1044, "annotation": "n_glycosylation_sequon" }, { "start_pos": 1057, "end_pos": 1059, "annotation": "n_glycosylation_sequon" }, { "start_pos": 656, "end_pos": 658, "annotation": "n_glycosylation_sequon" }, { "start_pos": 695, "end_pos": 697, "annotation": "n_glycosylation_sequon" }, { "start_pos": 778, "end_pos": 780, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [ { "id": "13065", "name": "", "equation": "ATP + H2O = ADP + phosphate + H(+)", "summary": "", "cellular_location": "", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [ "A0AAA9S5G9-1", "F1MWZ4-1", "A0AAA9SX42-1", "A0AAA9RXI8-1", "A0AAF6DLT1-1", "A6QLE5-1", "F1MSG2-1", "F6QYF9-1", "A0A3Q1MR04-1", "Q05B79-1", "E1BDN4-1", "A0AAA9U2H6-1", "A0AAA9TGZ3-1", "A4K436-1", "Q5E9H5-1", "A0A3Q1LTL4-1", "A6QLJ0-1", "A0A3Q1LSH0-1", "Q3SZ54-1", "A0AAF6Z0U5-1", "F1N079-1", "F6R6W2-1", "A0A3Q1MR43-1", "A0AAA9TT64-1", "Q0V8H6-1", "A0AAF6Z733-1", "Q2KJI7-1", "P09487-1", "P19120-1", "Q0IIK5-1", "A0AAF6YVB0-1", "Q2KIZ8-1", "P63258-1", "A1A4H6-1", "A7YSY2-1", "A0A3Q1LG16-1", "A0AAA9RUK3-1", "Q1RMT1-1", "G3X757-1", "F1MN01-1", "A0AAA9TT27-1", "A0ABI0NX25-1", "F1MB25-1", "F1MEM4-1", "A0A3Q1M0A4-1", "A0A3Q1MU57-1", "A5D7C1-1", "A0AAA9SPF3-1", "A0A3Q1M155-1", "E1BAN8-1", "A0A3Q1MS44-1", "F1MSD2-1", "O18956-1", "Q76LV2-1", "A4FUD9-1", "A5PJA1-1", "A6QQR4-1", "Q32LC7-1", "Q3ZBT1-1", "Q3ZC07-1", "Q5W5U4-1", "E1B9N7-1", "G3N268-1", "E1BKM5-1", "P35071-1", "P60712-1", "P62739-1", "P68138-1", "Q0V8B7-1", "Q0VD48-1", "Q17R09-1", "Q29S22-1", "Q2NKY8-1", "Q2TBU9-1", "Q3B7N1-1", "Q0VCX2-1", "Q28141-1", "Q2NL22-1", "Q3T147-1", "Q3ZBH9-1", "Q3ZBV2-1", "Q3ZC91-1", "Q5E9B5-1", "Q5E9N5-1", "Q1LZ78-1", "E1BH89-1", "F1MNU7-1", "A0ABI0NSA6-1", "F1N533-1", "Q2NL08-1", "E1BF68-1", "F1MW45-1", "F1N272-1", "Q2TBP1-1", "Q3SZ40-1", "Q3SZ65-1", "A0AAA9RRF7-1", "A0ABI0P467-1", "A5PJI5-1", "A0AAA9T674-1", "Q95M18-1", "Q3ZCH0-1", "F1MMS0-1", "E1BH78-1", "A0ABI0P3F2-1", "A0AAF6DLQ5-1", "G3MYF0-1", "A0A3Q1LQN7-1", "A0ABI0NXS3-1", "A0A3Q1M7R9-1", "A0A3Q1LT80-1", "Q9TTA5-1", "Q3ZBH0-1", "Q2HJF8-1", "Q2NKZ1-1", "Q2T9X2-1", "Q32L40-1", "A7Z019-1", "F6QHI8-1", "E1BDM8-1", "E1BNG3-1", "E1BP01-1", "F1MRW7-1", "A0A3Q1LV49-1", "F1MWM0-1", "Q3MHL7-1", "Q3T0K2-1", "Q5E9M9-1", "Q3ZCI9-1", "F1MYC6-1", "F1MUT6-1", "A0A3Q1M493-1", "A0A3Q1LXD0-1", "F1N155-1", "E1BII7-1", "E1BPG1-1", "F1MMK3-1", "F1MSI6-1", "F1N1A2-1", "A0A3Q1NMG4-1", "A0AAA9STQ6-1", "A0AAA9T2L7-1", "F1MMD5-1", "A0A3Q1LQC3-1", "A0AAA9T8W7-1", "E1B887-1", "F1MLB2-1", "E1BPX4-1", "F1N2W9-1", "E1BB03-1", "E1BMP7-1", "A0JND9-1", "E1BAS6-1", "A0AAA9RXM7-1", "Q59HJ6-1", "Q2KJ94-1", "A0A3Q1MDD8-1", "G3X6Y8-1", "A0AAF6Z0E4-1", "G3MZH7-1", "F1MKC7-1", "A0AAA9S7V9-1", "A0AAF6YME1-1", "F1MFR1-1", "Q3T084-1", "E1B7X9-1", "A0ABI0P204-1" ], "evidence": [ { "id": "13065", "database": "Rhea", "url": "https://www.rhea-db.org/rhea/13065" } ] } ], "reaction_participants": [], "reaction_enzymes": [ { "uniprot_ac": "A0A3Q1LG16", "gene_name": "MCM4", "activity": [ { "ec_number": "3.6.4.12", "activity": "ATP + H2O = ADP + phosphate + H(+).", "evidence": [ { "id": "A0A3Q1LG16", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1LG16" } ] }, { "ec_number": "3.6.4.12", "activity": "", "evidence": [ { "id": "A0A3Q1LG16", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1LG16" } ] } ] }, { "uniprot_ac": "A0A3Q1LQC3", "gene_name": "HELQ", "activity": [ { "ec_number": "5.6.2.4", "activity": "ATP + H2O = ADP + phosphate + H(+).", "evidence": [ { "id": "A0A3Q1LQC3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1LQC3" } ] }, { "ec_number": "5.6.2.4", "activity": "", "evidence": [ { "id": "A0A3Q1LQC3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1LQC3" } ] } ] }, { "uniprot_ac": "A0A3Q1LQN7", "gene_name": "DDX17", "activity": [ { "ec_number": "3.6.4.13", "activity": "ATP + H2O = ADP + phosphate + H(+).", "evidence": [ { "id": "A0A3Q1LQN7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1LQN7" } ] }, { "ec_number": "3.6.4.13", "activity": "", "evidence": [ { "id": "A0A3Q1LQN7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1LQN7" } ] } ] }, { "uniprot_ac": "A0A3Q1LSH0", "gene_name": "MOV10L1", "activity": [ { "ec_number": "3.6.4.13", "activity": "ATP + H2O = ADP + phosphate + H(+).", "evidence": [ { "id": "A0A3Q1LSH0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1LSH0" } ] }, { "ec_number": "3.6.4.13", "activity": "", "evidence": [ { "id": "A0A3Q1LSH0", "database": "UniProtKB", "url": 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2'-deoxyribonucleoside 5'-triphosphate = DNA(n+1) + diphosphate.", "evidence": [ { "id": "A0A3Q1M493", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1M493" } ] }, { "ec_number": "3.6.4.12", "activity": "ATP + H2O = ADP + phosphate + H(+).", "evidence": [ { "id": "A0A3Q1M493", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1M493" } ] }, { "ec_number": "2.7.7.7", "activity": "", "evidence": [ { "id": "A0A3Q1M493", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1M493" } ] }, { "ec_number": "3.6.4.12", "activity": "", "evidence": [ { "id": "A0A3Q1M493", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1M493" } ] }, { "ec_number": "2.7.7.49", "activity": "", "evidence": [ { "id": "A0A3Q1M493", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1M493" } ] } ] }, { "uniprot_ac": "A0A3Q1M7R9", "gene_name": "DHX34", "activity": [ { "ec_number": "3.6.4.13", "activity": "ATP + H2O = ADP + phosphate + H(+).", "evidence": [ { "id": "A0A3Q1M7R9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1M7R9" } ] }, { "ec_number": "3.6.4.13", "activity": "", "evidence": [ { "id": "A0A3Q1M7R9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1M7R9" } ] } ] }, { "uniprot_ac": "A0A3Q1MDD8", "gene_name": "ENTPD3", "activity": [ { "ec_number": "3.6.1.5", "activity": "a 2'-deoxyribonucleoside 5'-triphosphate + 2 H2O = a 2'-deoxyribonucleoside 5'-phosphate + 2 phosphate + 2 H(+).", "evidence": [ { "id": "A0A3Q1MDD8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1MDD8" } ] }, { "ec_number": "3.6.1.5", "activity": "", "evidence": [ { "id": "A0A3Q1MDD8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1MDD8" } ] } ] }, { "uniprot_ac": "A0A3Q1MR04", "gene_name": "NSF", "activity": [ { "ec_number": "3.6.4.6", "activity": "ATP + H2O = ADP + phosphate + H(+).", "evidence": [ { "id": 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"activity": "", "evidence": [ { "id": "A0A3Q1MS44", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1MS44" } ] } ] }, { "uniprot_ac": "A0A3Q1MU57", "gene_name": "DDX54", "activity": [ { "ec_number": "3.6.4.13", "activity": "ATP + H2O = ADP + phosphate + H(+).", "evidence": [ { "id": "A0A3Q1MU57", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1MU57" } ] }, { "ec_number": "3.6.4.13", "activity": "", "evidence": [ { "id": "A0A3Q1MU57", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1MU57" } ] } ] }, { "uniprot_ac": "A0A3Q1NMG4", "gene_name": "DDX59", "activity": [ { "ec_number": "3.6.4.13", "activity": "ATP + H2O = ADP + phosphate + H(+).", "evidence": [ { "id": "A0A3Q1NMG4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1NMG4" } ] }, { "ec_number": "3.6.4.13", "activity": "", "evidence": [ { "id": "A0A3Q1NMG4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1NMG4" } ] } ] }, { "uniprot_ac": "A0AAA9RRF7", "gene_name": "DDX31", "activity": [ { "ec_number": "3.6.4.13", "activity": "ATP + H2O = ADP + phosphate + H(+).", "evidence": [ { "id": "A0AAA9RRF7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9RRF7" } ] }, { "ec_number": "3.6.4.13", "activity": "", "evidence": [ { "id": "A0AAA9RRF7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9RRF7" } ] } ] }, { "uniprot_ac": "A0AAA9RUK3", "gene_name": "MCM2", "activity": [ { "ec_number": "3.6.4.12", "activity": "ATP + H2O = ADP + phosphate + H(+).", "evidence": [ { "id": "A0AAA9RUK3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9RUK3" } ] }, { "ec_number": "3.6.4.12", "activity": "", "evidence": [ { "id": "A0AAA9RUK3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9RUK3" } ] } ] }, { "uniprot_ac": "A0AAA9RXI8", "gene_name": "SPATA5", "activity": [ { "ec_number": "3.6.4.6", "activity": "ATP + H2O = ADP + phosphate + H(+).", "evidence": [ { "id": "A0AAA9RXI8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9RXI8" } ] }, { "ec_number": "3.6.4.10", "activity": "ATP + H2O = ADP + phosphate + H(+).", "evidence": [ { "id": "A0AAA9RXI8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9RXI8" } ] }, { "ec_number": "3.6.4.10", "activity": "", "evidence": [ { "id": "A0AAA9RXI8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9RXI8" } ] }, { "ec_number": "3.6.4.6", "activity": "", "evidence": [ { "id": "A0AAA9RXI8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9RXI8" } ] } ] }, { "uniprot_ac": "A0AAA9RXM7", "gene_name": "HLTF", "activity": [ { "ec_number": "2.3.2.27", "activity": "S-ubiquitinyl-[E2 ubiquitin-conjugating enzyme]-L-cysteine + [acceptor protein]-L-lysine = [E2 ubiquitin-conjugating enzyme]-L-cysteine + N(6)-ubiquitinyl-[acceptor protein]-L-lysine.", "evidence": [ { "id": 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"activity": "", "evidence": [ { "id": "A0AAA9S7V9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9S7V9" } ] } ] }, { "uniprot_ac": "A0AAA9SPF3", "gene_name": "IFIH1", "activity": [ { "ec_number": "3.6.4.13", "activity": "ATP + H2O = ADP + phosphate + H(+).", "evidence": [ { "id": "A0AAA9SPF3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9SPF3" } ] }, { "ec_number": "3.6.4.13", "activity": "", "evidence": [ { "id": "A0AAA9SPF3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9SPF3" } ] } ] }, { "uniprot_ac": "A0AAA9STQ6", "gene_name": "G3BP1", "activity": [ { "ec_number": "3.6.4.12", "activity": "ATP + H2O = ADP + phosphate + H(+).", "evidence": [ { "id": "A0AAA9STQ6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9STQ6" } ] }, { "ec_number": "3.6.4.13", "activity": "ATP + H2O = ADP + phosphate + H(+).", "evidence": [ { "id": "A0AAA9STQ6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9STQ6" } ] }, { "ec_number": "3.6.4.12", "activity": "", "evidence": [ { "id": "A0AAA9STQ6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9STQ6" } ] }, { "ec_number": "3.6.4.13", "activity": "", "evidence": [ { "id": "A0AAA9STQ6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9STQ6" } ] } ] }, { "uniprot_ac": "A0AAA9SX42", "gene_name": "TDRD12", "activity": [ { "ec_number": "3.6.4.13", "activity": "ATP + H2O = ADP + phosphate + H(+).", "evidence": [ { "id": "A0AAA9SX42", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9SX42" } ] }, { "ec_number": "3.6.4.13", "activity": "", "evidence": [ { "id": "A0AAA9SX42", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9SX42" } ] } ] }, { "uniprot_ac": "A0AAA9T2L7", "gene_name": "DDX11", "activity": [ { "ec_number": "5.6.2.3", "activity": "Couples ATP hydrolysis with the unwinding of duplex DNA at the 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"ec_number": "3.6.4.13", "activity": "", "evidence": [ { "id": "E1BF68", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BF68" } ] } ] }, { "uniprot_ac": "E1BH78", "gene_name": "SNRNP200", "activity": [ { "ec_number": "3.6.4.13", "activity": "ATP + H2O = ADP + phosphate + H(+).", "evidence": [ { "id": "E1BH78", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BH78" } ] }, { "ec_number": "3.6.4.13", "activity": "", "evidence": [ { "id": "E1BH78", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BH78" } ] } ] }, { "uniprot_ac": "E1BH89", "gene_name": "MCM6", "activity": [ { "ec_number": "3.6.4.12", "activity": "ATP + H2O = ADP + phosphate + H(+).", "evidence": [ { "id": "E1BH89", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BH89" } ] }, { "ec_number": "3.6.4.12", "activity": "", "evidence": [ { "id": "E1BH89", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BH89" } ] } ] }, { 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"https://www.uniprot.org/uniprotkb/E1BMP7" } ] }, { "ec_number": "5.6.2.3", "activity": "Couples ATP hydrolysis with the unwinding of duplex DNA at the replication fork by translocating in the 5'-3' direction.", "evidence": [ { "id": "E1BMP7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BMP7" } ] } ] }, { "uniprot_ac": "E1BNG3", "gene_name": "ascc3", "activity": [ { "ec_number": "5.6.2.4", "activity": "ATP + H2O = ADP + phosphate + H(+).", "evidence": [ { "id": "E1BNG3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BNG3" } ] }, { "ec_number": "5.6.2.4", "activity": "", "evidence": [ { "id": "E1BNG3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BNG3" } ] } ] }, { "uniprot_ac": "E1BP01", "gene_name": "MYO3A", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "E1BP01", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BP01" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "E1BP01", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BP01" } ] } ] }, { "uniprot_ac": "E1BPG1", "gene_name": "ZGRF1", "activity": [ { "ec_number": "5.6.2.3", "activity": "Couples ATP hydrolysis with the unwinding of duplex DNA at the replication fork by translocating in the 5'-3' direction.", "evidence": [ { "id": "E1BPG1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BPG1" } ] }, { "ec_number": "5.6.2.3", "activity": "", "evidence": [ { "id": "E1BPG1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BPG1" } ] } ] }, { "uniprot_ac": "E1BPX4", "gene_name": "MCM8", "activity": [ { "ec_number": "5.6.2.4", "activity": "ATP + H2O = ADP + phosphate + H(+).", "evidence": [ { "id": "E1BPX4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BPX4" } ] }, { "ec_number": "5.6.2.4", "activity": "", "evidence": [ { "id": "E1BPX4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BPX4" } ] } ] }, { "uniprot_ac": "F1MB25", "gene_name": "ENTPD1", "activity": [ { "ec_number": "3.6.1.5", "activity": "a 2'-deoxyribonucleoside 5'-triphosphate + 2 H2O = a 2'-deoxyribonucleoside 5'-phosphate + 2 phosphate + 2 H(+).", "evidence": [ { "id": "F1MB25", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MB25" } ] }, { "ec_number": "3.6.1.5", "activity": "", "evidence": [ { "id": "F1MB25", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MB25" } ] } ] }, { "uniprot_ac": "F1MEM4", "gene_name": "DHX8", "activity": [ { "ec_number": "3.6.4.13", "activity": "ATP + H2O = ADP + phosphate + H(+).", "evidence": [ { "id": "F1MEM4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MEM4" } ] }, { "ec_number": "3.6.4.13", "activity": "", "evidence": [ { "id": "F1MEM4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MEM4" } ] } ] }, { "uniprot_ac": "F1MFR1", "gene_name": "HFM1", "activity": [ { "ec_number": "5.6.2.4", "activity": "ATP + H2O = ADP + phosphate + H(+).", "evidence": [ { "id": "F1MFR1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MFR1" } ] }, { "ec_number": "5.6.2.4", "activity": "", "evidence": [ { "id": "F1MFR1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MFR1" } ] } ] }, { "uniprot_ac": "F1MKC7", "gene_name": "HELZ", "activity": [ { "ec_number": "3.6.4.13", "activity": "ATP + H2O = ADP + phosphate + H(+).", "evidence": [ { "id": "F1MKC7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MKC7" } ] }, { "ec_number": "3.6.4.13", "activity": "", "evidence": [ { "id": "F1MKC7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MKC7" } ] } ] }, { "uniprot_ac": "F1MLB2", "gene_name": "CHD8", "activity": [ { "ec_number": "3.6.4.-", "activity": "", "evidence": [ { "id": "F1MLB2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MLB2" } ] } ] }, { "uniprot_ac": "F1MMD5", "gene_name": "XRCC6", "activity": [ { "ec_number": "4.2.99.18", "activity": "2'-deoxyribonucleotide-(2'-deoxyribose 5'-phosphate)-2'-deoxyribonucleotide-DNA = a 3'-end 2'-deoxyribonucleotide-(2,3-dehydro-2,3-deoxyribose 5'-phosphate)-DNA + a 5'-end 5'-phospho-2'-deoxyribonucleoside-DNA + H(+).", "evidence": [ { "id": "F1MMD5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MMD5" } ] }, { "ec_number": "5.6.2.4", "activity": "ATP + H2O = ADP + phosphate + H(+).", "evidence": [ { "id": "F1MMD5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MMD5" } ] }, { "ec_number": "5.6.2.4", "activity": "", "evidence": [ { "id": "F1MMD5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MMD5" } ] }, { "ec_number": "4.2.99.18", "activity": "", "evidence": [ { "id": "F1MMD5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MMD5" } ] }, { "ec_number": "3.6.4.12", "activity": "ATP + H2O = ADP + phosphate + H(+).", "evidence": [ { "id": "F1MMD5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MMD5" } ] }, { "ec_number": "3.6.4.12", "activity": "", "evidence": [ { "id": "F1MMD5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MMD5" } ] } ] }, { "uniprot_ac": "F1MMK3", "gene_name": "DDX50", "activity": [ { "ec_number": "3.6.4.13", "activity": "ATP + H2O = ADP + phosphate + H(+).", "evidence": [ { "id": "F1MMK3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MMK3" } ] }, { "ec_number": "3.6.4.13", "activity": "", "evidence": [ { "id": "F1MMK3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MMK3" } ] } ] }, { "uniprot_ac": "F1MMS0", "gene_name": "BRIP1", "activity": [ { "ec_number": "5.6.2.3", "activity": "Couples ATP hydrolysis with the unwinding of duplex DNA at the replication fork by translocating in the 5'-3' direction.", "evidence": [ { "id": "F1MMS0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MMS0" } ] }, { "ec_number": "5.6.2.3", "activity": "", "evidence": [ { "id": "F1MMS0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MMS0" } ] } ] }, { "uniprot_ac": "F1MN01", "gene_name": "CFTR", "activity": [ { "ec_number": "5.6.1.6", "activity": "ATP + H2O + closed Cl(-) channel = ADP + phosphate + open Cl(-) channel.", "evidence": [ { "id": "F1MN01", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MN01" } ] }, { "ec_number": "5.6.1.6", "activity": "", "evidence": [ { "id": "F1MN01", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MN01" } ] } ] }, { "uniprot_ac": "F1MNU7", "gene_name": "YTHDC2", "activity": [ { "ec_number": "3.6.4.13", "activity": "ATP + H2O = ADP + phosphate + H(+).", "evidence": [ { "id": "F1MNU7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MNU7" } ] }, { "ec_number": "3.6.4.13", "activity": "", "evidence": [ { "id": "F1MNU7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MNU7" } ] } ] }, { "uniprot_ac": "F1MRW7", "gene_name": "DDX20", "activity": [ { "ec_number": "3.6.1.15", "activity": "a ribonucleoside 5'-triphosphate + H2O = a ribonucleoside 5'-diphosphate + phosphate + H(+).", "evidence": [ { "id": "F1MRW7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MRW7" } ] }, { "ec_number": "3.6.4.13", "activity": "ATP + H2O = ADP + phosphate + H(+).", "evidence": [ { "id": "F1MRW7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MRW7" } ] }, { "ec_number": "3.6.4.13", "activity": "", "evidence": [ { "id": "F1MRW7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MRW7" } ] }, { "ec_number": "3.6.1.15", "activity": "", "evidence": [ { "id": "F1MRW7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MRW7" } ] } ] }, { "uniprot_ac": "F1MSD2", "gene_name": "RUVBL2", "activity": [ { "ec_number": "3.6.4.12", "activity": "ATP + H2O = ADP + phosphate + H(+).", "evidence": [ { "id": "F1MSD2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MSD2" } ] }, { "ec_number": "3.6.4.12", "activity": "", "evidence": [ { "id": "F1MSD2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MSD2" } ] } ] }, { "uniprot_ac": "F1MSG2", "gene_name": "FBH1", "activity": [ { "ec_number": "5.6.2.4", "activity": "ATP + H2O = ADP + phosphate + H(+).", "evidence": [ { "id": "F1MSG2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MSG2" } ] }, { "ec_number": "5.6.2.4", "activity": "", "evidence": [ { "id": "F1MSG2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MSG2" } ] } ] }, { "uniprot_ac": "F1MSI6", "gene_name": "DDX25", "activity": [ { "ec_number": "3.6.4.13", "activity": "ATP + H2O = ADP + phosphate + H(+).", "evidence": [ { "id": "F1MSI6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MSI6" } ] }, { "ec_number": "3.6.4.13", "activity": "", "evidence": [ { "id": "F1MSI6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MSI6" } ] } ] }, { "uniprot_ac": "F1MUT6", "gene_name": "DDX19B", "activity": [ { "ec_number": "3.6.4.13", "activity": "ATP + H2O = ADP + phosphate + H(+).", "evidence": [ { "id": "F1MUT6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MUT6" } ] }, { "ec_number": "3.6.4.13", "activity": "", "evidence": [ { "id": "F1MUT6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MUT6" } ] } ] }, { "uniprot_ac": "F1MW45", "gene_name": "DDX55", "activity": [ { "ec_number": "3.6.4.13", "activity": "ATP + H2O = ADP + phosphate + H(+).", "evidence": [ { "id": "F1MW45", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MW45" } ] }, { "ec_number": "3.6.4.13", "activity": "", "evidence": [ { "id": "F1MW45", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MW45" } ] } ] }, { "uniprot_ac": "F1MWM0", "gene_name": "ABCA4", "activity": [ { "ec_number": "7.6.2.1", "activity": "ATP + H2O + phospholipidSide 1 = ADP + phosphate + phospholipidSide 2.", "evidence": [ { "id": "F1MWM0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MWM0" } ] }, { "ec_number": "7.6.2.1", "activity": "", "evidence": [ { "id": "F1MWM0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MWM0" } ] } ] }, { "uniprot_ac": "F1MWZ4", "gene_name": "DHX33", "activity": [ { "ec_number": "3.6.4.13", "activity": "ATP + H2O = ADP + phosphate + H(+).", "evidence": [ { "id": "F1MWZ4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MWZ4" } ] }, { "ec_number": "3.6.4.13", "activity": "", "evidence": [ { "id": "F1MWZ4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MWZ4" } ] } ] }, { "uniprot_ac": "F1MYC6", "gene_name": "DDX4", "activity": [ { "ec_number": "3.6.4.13", "activity": "ATP + H2O = ADP + phosphate + H(+).", "evidence": [ { "id": "F1MYC6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MYC6" } ] }, { "ec_number": "3.6.4.13", "activity": "", "evidence": [ { "id": "F1MYC6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MYC6" } ] } ] }, { "uniprot_ac": "F1N079", "gene_name": "RTEL1", "activity": [ { "ec_number": "5.6.2.-", "activity": "", "evidence": [ { "id": "F1N079", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1N079" } ] } ] }, { "uniprot_ac": "F1N155", "gene_name": "CLPX", "activity": [ { "ec_number": "3.6.4.10", "activity": "ATP + H2O = ADP + phosphate + H(+).", "evidence": [ { "id": "F1N155", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1N155" } ] }, { "ec_number": "3.6.4.10", "activity": "", "evidence": [ { "id": "F1N155", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1N155" } ] } ] }, { "uniprot_ac": "F1N1A2", "gene_name": "DHX57", "activity": [ { "ec_number": "3.6.4.13", "activity": "ATP + H2O = ADP + phosphate + H(+).", "evidence": [ { "id": "F1N1A2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1N1A2" } ] }, { "ec_number": "3.6.4.13", "activity": "", "evidence": [ { "id": "F1N1A2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1N1A2" } ] } ] }, { "uniprot_ac": "F1N272", "gene_name": "ATP13A4", "activity": [ { "ec_number": "7.2.2.-", "activity": "", "evidence": [ { "id": "F1N272", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1N272" } ] } ] }, { "uniprot_ac": "F1N2W9", "gene_name": "MCM9", "activity": [ { "ec_number": "5.6.2.4", "activity": "ATP + H2O = ADP + phosphate + H(+).", "evidence": [ { "id": "F1N2W9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1N2W9" } ] }, { "ec_number": "5.6.2.4", "activity": "", "evidence": [ { "id": "F1N2W9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1N2W9" } ] } ] }, { "uniprot_ac": "F1N533", "gene_name": "DDX18", "activity": [ { "ec_number": "3.6.4.13", "activity": "ATP + H2O = ADP + phosphate + H(+).", "evidence": [ { "id": "F1N533", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1N533" } ] }, { "ec_number": "3.6.4.13", "activity": "", "evidence": [ { "id": "F1N533", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1N533" } ] } ] }, { "uniprot_ac": "F6QHI8", "gene_name": "DDX21", "activity": [ { "ec_number": "3.6.4.13", "activity": "ATP + H2O = ADP + phosphate + H(+).", "evidence": [ { "id": "F6QHI8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F6QHI8" } ] }, { "ec_number": "3.6.4.13", "activity": "", "evidence": [ { "id": "F6QHI8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F6QHI8" } ] } ] }, { "uniprot_ac": "F6QYF9", "gene_name": "DDX41", "activity": [ { "ec_number": "3.6.4.13", "activity": "ATP + H2O = ADP + phosphate + H(+).", "evidence": [ { "id": "F6QYF9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F6QYF9" } ] }, { "ec_number": "3.6.4.13", "activity": "", "evidence": [ { "id": "F6QYF9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F6QYF9" } ] } ] }, { "uniprot_ac": "F6R6W2", "gene_name": "DDX23", "activity": [ { "ec_number": "3.6.4.13", "activity": "ATP + H2O = ADP + phosphate + H(+).", "evidence": [ { "id": "F6R6W2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F6R6W2" } ] }, { "ec_number": "3.6.4.13", "activity": "", "evidence": [ { "id": "F6R6W2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F6R6W2" } ] } ] }, { "uniprot_ac": "G3MYF0", "gene_name": "DDX53", "activity": [ { "ec_number": "3.6.4.13", "activity": "ATP + H2O = ADP + phosphate + H(+).", "evidence": [ { "id": "G3MYF0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3MYF0" } ] }, { "ec_number": "3.6.4.13", "activity": "", "evidence": [ { "id": "G3MYF0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3MYF0" } ] } ] }, { "uniprot_ac": "G3MZH7", "gene_name": "ENTPD2", "activity": [ { "ec_number": "3.6.1.5", "activity": "a 2'-deoxyribonucleoside 5'-triphosphate + 2 H2O = a 2'-deoxyribonucleoside 5'-phosphate + 2 phosphate + 2 H(+).", "evidence": [ { "id": "G3MZH7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3MZH7" } ] }, { "ec_number": "3.6.1.5", "activity": "", "evidence": [ { "id": "G3MZH7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3MZH7" } ] } ] }, { "uniprot_ac": "G3N268", "gene_name": "DHX58", "activity": [ { "ec_number": "3.6.4.13", "activity": "ATP + H2O = ADP + phosphate + H(+).", "evidence": [ { "id": "G3N268", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3N268" } ] }, { "ec_number": "3.6.4.13", "activity": "", 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"activity": "ATP + H2O = ADP + phosphate + H(+).", "evidence": [ { "id": "Q2NL22", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q2NL22" } ] }, { "ec_number": "3.6.4.13", "activity": "", "evidence": [ { "id": "Q2NL22", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q2NL22" } ] } ] }, { "uniprot_ac": "Q2T9X2", "gene_name": "CCT4", "activity": [ { "ec_number": "3.6.1.-", "activity": "", "evidence": [ { "id": "Q2T9X2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q2T9X2" } ] } ] }, { "uniprot_ac": "Q2TBP1", "gene_name": "DDX25", "activity": [ { "ec_number": "3.6.4.13", "activity": "ATP + H2O = ADP + phosphate + H(+).", "evidence": [ { "id": "Q2TBP1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q2TBP1" } ] }, { "ec_number": "3.6.4.13", "activity": "", "evidence": [ { "id": "Q2TBP1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q2TBP1" } ] } ] }, { "uniprot_ac": "Q2TBU9", "gene_name": 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"1-hexadecanoyl-2-(9Z,12Z-octadecadienoyl)-sn-glycero-3-phosphoethanolamine + H2O = 1-hexadecanoyl-sn-glycero-3-phosphoethanolamine + (9Z,12Z)-octadecadienoate + H(+)", "summary": "", "cellular_location": "", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [ "P00593-1", "E1BEM2-1", "E1BLF3-1", "Q56JZ2-1", "E1B9V3-1", "E1BEG8-1", "A0AAA9T9W1-1", "G3N3U6-1", "Q1JPB9-1", "A0A3Q1LNM7-1", "F1MSG5-1", "F6RTH3-1", "A0AAA9TQC6-1" ], "evidence": [ { "id": "40815", "database": "Rhea", "url": "https://www.rhea-db.org/rhea/40815" } ] }, { "id": "40919", "name": "", "equation": "1-hexadecanoyl-2-(9Z-octadecenoyl)-sn-glycero-3-phospho-(1'-sn-glycerol) + H2O = 1-hexadecanoyl-sn-glycero-3-phospho-(1'-sn-glycerol) + (9Z)-octadecenoate + H(+)", "summary": "", "cellular_location": "", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [ "Q8WMP9-1", "P00593-1", "A0A3Q1LV96-1", "E1BLF3-1", "Q56JZ2-1", "E1B9V3-1", "E1BEG8-1", "A0AAA9T9W1-1", "G3N3U6-1", 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"evidence": [ { "id": "Q8WMP9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q8WMP9" } ] } ] } ], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "G3N3U6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3N3U6" }, { "id": "SM00085", "database": "SMART", "url": "http://smart.embl.de/smart/do_annotation.pl?DOMAIN=SM00085" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "Phospholipase A2-like central", "eco_id": "ECO_0000259", "start_pos": 21, "end_pos": 137, "start_aa": "Asp", "end_aa": "Glu", "glycosite_overlap": [] } ], "binding_sites": [ { "evidence": [ { "id": "G3N3U6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3N3U6" }, { "id": "PIRSR601211-2", "database": "PIR Site Rule", "url": "https://proteininformationresource.org/cgi-bin/pirrule?id=PIRSR601211-2" } ], "binding_site_uniprot": 47, "amino_acid": "Tyr", "chebi_lig_id": "CHEBI:29108", "ligand": "Ca(2+)", "ligand_label": "", "uniprotkb_ligand_comment": "", "eco_id": "ECO_0000256", "start_pos": 47, "end_pos": 47, "start_aa": "Tyr", "end_aa": "Tyr", "glycosite_overlap": [] }, { "evidence": [ { "id": "G3N3U6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3N3U6" }, { "id": "PIRSR601211-2", "database": "PIR Site Rule", "url": "https://proteininformationresource.org/cgi-bin/pirrule?id=PIRSR601211-2" } ], "binding_site_uniprot": 51, "amino_acid": "Gly", "chebi_lig_id": "CHEBI:29108", "ligand": "Ca(2+)", "ligand_label": "", "uniprotkb_ligand_comment": "", "eco_id": "ECO_0000256", "start_pos": 51, "end_pos": 51, "start_aa": "Gly", "end_aa": "Gly", "glycosite_overlap": [] } ], "synthesized_glycans": [], "enzyme_annotation": [ { "ec_number": "3.1.1.4", "ec_name": "a 1-O-alkyl-2-acyl-sn-glycero-3-phosphocholine + H2O = a 1-O-alkyl-sn-glycero-3-phosphocholine + a fatty acid + H(+).", "evidence": [ { "id": "3.1.1.4", "database": "Rhea", "url": "https://www.rhea-db.org/rhea/?query=ec:3.1.1.4" }, { "id": "3.1.1.4", "database": "BRENDA Enzymes", "url": "https://www.brenda-enzymes.org/enzyme.php?ecno=3.1.1.4" } ] } ], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": 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"database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G1K218/entry#names_and_taxonomy" } ] }, { "name": "2.7.10.1", "type": "synonym", "evidence": [ { "id": "G1K218", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G1K218/entry#names_and_taxonomy" } ] } ], "function": [], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Bos taurus", "taxid": 9913, "evidence": [ { "database": "UniProtKB", "id": "G1K218", "url": "https://www.uniprot.org/uniprotkb/G1K218" } ], "common_name": "Bovine", "glygen_name": "Bovine", "reference_species": "Bos taurus [9913]" } ], "gene": [ { "name": "IGF1R", "url": "https://www.uniprot.org/uniprotkb/G1K218", "locus": { "chromosome": "21", "start_pos": 8080394, "end_pos": 7780293, "strand": "-", "evidence": [ { "database": "Ensembl Gene", "id": "ENSBTAG00000021527", "url": "https://www.ensembl.org/id/ENSBTAG00000021527" } ] } } ], "crossref": [ { "id": 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Classification" ] }, { "id": "IPR036941", "url": "https://www.ebi.ac.uk/interpro/entry/IPR036941", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR050122", "url": "https://www.ebi.ac.uk/interpro/entry/IPR050122", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "FRGYAFK", "url": "https://omabrowser.org/oma/group/FRGYAFK/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "A0A3Q1NB49", "url": "https://www.orthodb.org/?gene=A0A3Q1NB49", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "G1K218", "url": "https://www.orthodb.org/?gene=G1K218", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR24416", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR24416", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR24416:SF106", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR24416:SF106", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00757", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00757", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF01030", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF01030", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF07714", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF07714", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "R-BTA-2404192", "url": "https://www.reactome.org/PathwayBrowser/#R-BTA-2404192", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "R-BTA-2428928", "url": "https://www.reactome.org/PathwayBrowser/#R-BTA-2428928", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "R-BTA-2428933", "url": "https://www.reactome.org/PathwayBrowser/#R-BTA-2428933", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "R-BTA-9009391", "url": "https://www.reactome.org/PathwayBrowser/#R-BTA-9009391", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "10596", "url": "https://www.rhea-db.org/rhea/10596", "database": "Rhea", "categories": [ "Enzyme and Pathway" ] }, { "id": "A0A3Q1NB49", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1NB49", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A3Q1NB49-1", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1NB49-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0ABI0NML8", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NML8", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0ABI0NML8-1", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NML8-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "G1K218", "url": "https://www.uniprot.org/uniprotkb/G1K218", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "G1K218-1", "url": "https://www.uniprot.org/uniprotkb/G1K218-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MKSSSGGGSPTSLWGLLFFSAALSLWPTSGEICGPGIDIRNDYQQLKRLENCTVIEGYLHILLISKAEDYRSYRFPKLTVITEYLLLFRVAGLESLGDLFPNLTVIRGWKLFYNYALVIFEMTNLKDIGLYNLRNITRGAIRIEKNADLCYLSTVDWSLILDAASNNYIVGNKPPKECGDLCPGTMEEKPLCEKTTINNEYSYRCWTTNRCQKMCPSACGKRACTETHECCHPECLGSCSAPDNATACVACRHYYYAGVCVPSCPPNTYRFEGWRCVDRDFCANIPNAESSDSEGFVIHDGECMQECPSGFIRNGSQSMYCIPCEGPCPKVCEEEKKTKTIDSVTSAQMLQGCTIFKGNLLINIRRGNNIASELENFMGLIEVVTGYVKIRHSHALVSLSFLKNLRQILGEEQLEGNYSFYVLDNQNLQQLWDWDHRNLTIKAGKMYFAFNPKLCVSEIYRMEEVTGTKGRQSKGDINTRNNGERASCESDVLHFTSTTTSKNRIIITWHRYRPPDYRDLISFTVYYKEAPFKNVTEYDGQDACGSNSWNMVDVDLPPNKDVEPGILLHGLKPWTQYAVYVKAVTLTMVENDHIRGAKSEILYIRTNASVPSIPLDVLSASNSSSQLIVKWNPPSLPNGNLSYYIVRWQRQPQDSYLYRHNYCSKDKIPIRKYADGTIDVEEVTENPKTEVCGGEKGPCCACPKTEAEKQAEKEEAEYRKVFENFLHNAIFVPRPERKRREVMQIANTTMSSRSRNTTVLDTYNITDPEELETEYPFFESRVDNKERTVISNLRPFTLYRIDIHSCNHEAEKLGCSASNFVFARTMPAEGADDIPGPVTWEPRPENSIFLKWPEPENPNGLILMYEIKYGSQVEDQRECVSRQEYRKYGGAKLNRLNPGNYTARIQATSLSGNGSWTDPVFFYVQAKTTYENFIHLMIALPIAVLLIVGGLVIMLYVFHRKRNSSRLGNGVLYASVNPEYFSAADVYVPDEWEVAREKITMSRELGQGSFGMVYEGVAKGVVKDEPETRVAIKTVNEAASMRERIEFLNEASVMKEFNCHHVVRLLGVVSQGQPTLVIMELMTRGDLKSYLRSLRPEMENNPVLAPPSLSKMIQMAGEIADGMAYLNANKFVHRDLAARNCMVAEDFTVKIGDFGMTRDIYETDYYRKGGKGLLPVRWMSPESLKDGVFTTHSDVWSFGVVLWEIATLAEQPYQGLSNEQVLRFVMEGGLLDKPDNCPDMLFELMRMCWQYNPKMRPSFLEIISSVKDEMEAGFREVSFYYSEENKPPEPEELDLEPENMESVPLDPSASSASLPLPDRHSGHKAENGPGPGVLVLRASFDERQPYAHMNGGRKNERALPLPQSSTC", "length": 1367, "header": "tr|G1K218-1|G1K218_BOVIN Isoform 1 of Tyrosine-protein kinase receptor OS=Bos taurus OX=9913 GN=IGF1R PE=3 SV=3 CANONICAL=G1K218-1" }, "isoforms": [ { "isoform_ac": "A0A3Q1NB49-1", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1NB49/entry", "sequence": { "sequence": "MGILQTRILEWVAILSSRVSSQPRDQTQFSCIASRFFTGEAQEYWICGPGIDIRNDYQQLKRLENCTVIEGYLHILLISKAEDYRSYRFPKLTVITEYLLLFRVAGLESLGDLFPNLTVIRGWKLFYNYALVIFEMTNLKDIGLYNLRNITRGAIRIEKNADLCYLSTVDWSLILDAASNNYIVGNKPPKECGDLCPGTMEEKPLCEKTTINNEYSYRCWTTNRCQKMCPSACGKRACTETHECCHPECLGSCSAPDNATACVACRHYYYAGVCVPSCPPNTYRFEGWRCVDRDFCANIPNAESSDSEGFVIHDGECMQECPSGFIRNGSQSMYCIPCEGPCPKVCEEEKKTKTIDSVTSAQMLQGCTIFKGNLLINIRRGNNIASELENFMGLIEVVTGYVKIRHSHALVSLSFLKNLRQILGEEQLEGNYSFYVLDNQNLQQLWDWDHRNLTIKAGKMYFAFNPKLCVSEIYRMEEVTGTKGRQSKGDINTRNNGERASCESDVLHFTSTTTSKNRIIITWHRYRPPDYRDLISFTVYYKEAPFKNVTEYDGQDACGSNSWNMVDVDLPPNKDVEPGILLHGLKPWTQYAVYVKAVTLTMVENDHIRGAKSEILYIRTNASVPSIPLDVLSASNSSSQLIVKWNPPSLPNGNLSYYIVRWQRQPQDSYLYRHNYCSKDKIPIRKYADGTIDVEEVTENPKTEVCGGEKGPCCACPKTEAEKQAEKEEAEYRKVFENFLHNAIFVPRPERKRREVMQIANTTMSSRSRNTTVLDTYNITDPEELETEYPFFESRVDNKERTVISNLRPFTLYRIDIHSCNHEAEKLGCSASNFVFARTMPAEGADDIPGPVTWEPRPENSIFLKWPEPENPNGLILMYEIKYGSQVEDQRECVSRQEYRKYGGAKLNRLNPGNYTARIQATSLSGNGSWTDPVFFYVQAKTTYENFIHLMIALPIAVLLIVGGLVIMLYVFHRKRNSSRLGNGVLYASVNPEYFSAADVYVPDEWEVAREKITMSRELGQGSFGMVYEGVAKGVVKDEPETRVAIKTVNEAASMRERIEFLNEASVMKEFNCHHVVRLLGVVSQGQPTLVIMELMTRGDLKSYLRSLRPEMENNPVLAPPSLSKMIQMAGEIADGMAYLNANKFVHRDLAARNCMVAEDFTVKIGDFGMTRDIYETDYYRKGGKGLLPVRWMSPESLKDGVFTTHSDVWSFGVVLWEIATLAEQPYQGLSNEQVLRFVMEGGLLDKPDNCPDMLFELMRMCWQYNPKMRPSFLEIISSVKDEMEAGFREVSFYYSEENKPPEPEELDLEPENMESVPLDPSASSASLPLPDRHSGHKAENGPGPGVLVLRASFDERQPYAHMNGGRKNERALPLPQSSTC", "length": 1381, "header": "tr|A0A3Q1NB49-1|G1K218_BOVIN Computationally mapped isoform of Tyrosine-protein kinase receptor OS=Bos taurus OX=9913 GN=IGF1R PE=3 SV=2 CANONICAL=G1K218-1" }, "locus": { "chromosome": "21", "start_pos": 8080362, "end_pos": 7806647, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000073249.3", "url": "https://www.ensembl.org/id/ENSBTAT00000073249.3" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000068518.2", "url": "https://www.ensembl.org/id/ENSBTAP00000068518.2" } ] } }, { "isoform_ac": "A0ABI0NML8-1", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NML8/entry", "sequence": { "sequence": "MTNLKDIGLYNLRNITRGAIRIEKNADLCYLSTVDWSLILDAASNNYIVGNKPPKECGDLCPGTMEEKPLCEKTTINNEYSYRCWTTNRCQKMCPSACGKRACTETHECCHPECLGSCSAPDNATACVACRHYYYAGVCVPSCPPNTYRFEGWRCVDRDFCANIPNAESSDSEGFVIHDGECMQECPSGFIRNGSQSMYCIPCEGPCPKVCEEEKKTKTIDSVTSAQMLQGCTIFKGNLLINIRRGNNIASELENFMGLIEVVTGYVKIRHSHALVSLSFLKNLRQILGEEQLEGNYSFYVLDNQNLQQLWDWDHRNLTIKAGKMYFAFNPKLCVSEIYRMEEVTGTKGRQSKGDINTRNNGERASCESDVLHFTSTTTSKNRIIITWHRYRPPDYRDLISFTVYYKEAPFKNVTEYDGQDACGSNSWNMVDVDLPPNKDVEPGILLHGLKPWTQYAVYVKAVTLTMVENDHIRGAKSEILYIRTNASVPSIPLDVLSASNSSSQLIVKWNPPSLPNGNLSYYIVRWQRQPQDSYLYRHNYCSKDKIPIRKYADGTIDVEEVTENPKTEVCGGEKGPCCACPKTEAEKQAEKEEAEYRKVFENFLHNAIFVPRPERKRREVMQIANTTMSSRSRNTTVLDTYNITDPEELETEYPFFESRVDNKERTVISNLRPFTLYRIDIHSCNHEAEKLGCSASNFVFARTMPAEGADDIPGPVTWEPRPENSIFLKWPEPENPNGLILMYEIKYGSQVEDQRECVSRQEYRKYGGAKLNRLNPGNYTARIQATSLSGNGSWTDPVFFYVQAKTTYENFIHLMIALPIAVLLIVGGLVIMLYVFHRKRNSSRLGNGVLYASVNPEYFSAADVYVPDEWEVAREKITMSRELGQGSFGMVYEGVAKGVVKDEPETRVAIKTVNEAASMRERIEFLNEASVMKEFNCHHVVRLLGVVSQGQPTLVIMELMTRGDLKSYLRSLRPEMENNPVLAPPSLSKMIQMAGEIADGMAYLNANKFVHRDLAARNCMVAEDFTVKIGDFGMTRDIYETDYYRKGGKGLLPVRWMSPESLKDGVFTTHSDVWSFGVVLWEIATLAEQPYQGLSNEQVLRFVMEGGLLDKPDNCPDMLFELMRMCWQYNPKMRPSFLEIISSVKDEMEAGFREVSFYYSEENKPPEPEELDLEPENMESVPLDPSASSASLPLPDRHSGHKAENGPGPGVLVLRASFDERQPYAHMNGGRKNERALPLPQSSTC", "length": 1246, "header": "tr|A0ABI0NML8-1|A0ABI0NML8_BOVIN Computationally mapped isoform of Tyrosine-protein kinase receptor OS=Bos taurus OX=9913 GN=IGF1R PE=3 SV=1 CANONICAL=G1K218-1" }, "locus": { "chromosome": "21", "start_pos": 8080362, "end_pos": 7833364, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000154415.1", "url": "https://www.ensembl.org/id/ENSBTAT00000154415.1" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000106799.1", "url": "https://www.ensembl.org/id/ENSBTAP00000106799.1" } ] } }, { "isoform_ac": "G1K218-1", "url": "https://www.uniprot.org/uniprotkb/G1K218/entry", "sequence": { "sequence": "MKSSSGGGSPTSLWGLLFFSAALSLWPTSGEICGPGIDIRNDYQQLKRLENCTVIEGYLHILLISKAEDYRSYRFPKLTVITEYLLLFRVAGLESLGDLFPNLTVIRGWKLFYNYALVIFEMTNLKDIGLYNLRNITRGAIRIEKNADLCYLSTVDWSLILDAASNNYIVGNKPPKECGDLCPGTMEEKPLCEKTTINNEYSYRCWTTNRCQKMCPSACGKRACTETHECCHPECLGSCSAPDNATACVACRHYYYAGVCVPSCPPNTYRFEGWRCVDRDFCANIPNAESSDSEGFVIHDGECMQECPSGFIRNGSQSMYCIPCEGPCPKVCEEEKKTKTIDSVTSAQMLQGCTIFKGNLLINIRRGNNIASELENFMGLIEVVTGYVKIRHSHALVSLSFLKNLRQILGEEQLEGNYSFYVLDNQNLQQLWDWDHRNLTIKAGKMYFAFNPKLCVSEIYRMEEVTGTKGRQSKGDINTRNNGERASCESDVLHFTSTTTSKNRIIITWHRYRPPDYRDLISFTVYYKEAPFKNVTEYDGQDACGSNSWNMVDVDLPPNKDVEPGILLHGLKPWTQYAVYVKAVTLTMVENDHIRGAKSEILYIRTNASVPSIPLDVLSASNSSSQLIVKWNPPSLPNGNLSYYIVRWQRQPQDSYLYRHNYCSKDKIPIRKYADGTIDVEEVTENPKTEVCGGEKGPCCACPKTEAEKQAEKEEAEYRKVFENFLHNAIFVPRPERKRREVMQIANTTMSSRSRNTTVLDTYNITDPEELETEYPFFESRVDNKERTVISNLRPFTLYRIDIHSCNHEAEKLGCSASNFVFARTMPAEGADDIPGPVTWEPRPENSIFLKWPEPENPNGLILMYEIKYGSQVEDQRECVSRQEYRKYGGAKLNRLNPGNYTARIQATSLSGNGSWTDPVFFYVQAKTTYENFIHLMIALPIAVLLIVGGLVIMLYVFHRKRNSSRLGNGVLYASVNPEYFSAADVYVPDEWEVAREKITMSRELGQGSFGMVYEGVAKGVVKDEPETRVAIKTVNEAASMRERIEFLNEASVMKEFNCHHVVRLLGVVSQGQPTLVIMELMTRGDLKSYLRSLRPEMENNPVLAPPSLSKMIQMAGEIADGMAYLNANKFVHRDLAARNCMVAEDFTVKIGDFGMTRDIYETDYYRKGGKGLLPVRWMSPESLKDGVFTTHSDVWSFGVVLWEIATLAEQPYQGLSNEQVLRFVMEGGLLDKPDNCPDMLFELMRMCWQYNPKMRPSFLEIISSVKDEMEAGFREVSFYYSEENKPPEPEELDLEPENMESVPLDPSASSASLPLPDRHSGHKAENGPGPGVLVLRASFDERQPYAHMNGGRKNERALPLPQSSTC", "length": 1367, "header": "tr|G1K218-1|G1K218_BOVIN Isoform 1 of Tyrosine-protein kinase receptor OS=Bos taurus OX=9913 GN=IGF1R PE=3 SV=3 CANONICAL=G1K218-1" }, "locus": { "chromosome": "21", "start_pos": 8080362, "end_pos": 7780325, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000028690.7", "url": "https://www.ensembl.org/id/ENSBTAT00000028690.7" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000028690.6", "url": "https://www.ensembl.org/id/ENSBTAP00000028690.6" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [ "enzyme" ], "publication": [], "pathway": [ { "id": "R-BTA-2404192", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-BTA-2404192", "resource": "Reactome", "description": "Signaling by Type 1 Insulin-like Growth Factor 1 Receptor (IGF1R)" }, { "id": "R-BTA-2428928", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-BTA-2428928", "resource": "Reactome", "description": "IRS-related events triggered by IGF1R" }, { "id": "R-BTA-2428933", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-BTA-2428933", "resource": "Reactome", "description": "SHC-related events triggered by IGF1R" }, { "id": "R-BTA-9009391", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-BTA-9009391", "resource": "Reactome", "description": "Extra-nuclear estrogen signaling" } ], "orthologs": [ { "uniprot_canonical_ac": "P08069-1", "protein_name": "Insulin-like growth factor 1 receptor", "gene_name": "IGF1R", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MKSGSGGGSPTSLWGLLFLSAALSLWPTSGEICGPGIDIRNDYQQLKRLENCTVIEGYLHILLISKAEDYRSYRFPKLTVITEYLLLFRVAGLESLGDLFPNLTVIRGWKLFYNYALVIFEMTNLKDIGLYNLRNITRGAIRIEKNADLCYLSTVDWSLILDAVSNNYIVGNKPPKECGDLCPGTMEEKPMCEKTTINNEYNYRCWTTNRCQKMCPSTCGKRACTENNECCHPECLGSCSAPDNDTACVACRHYYYAGVCVPACPPNTYRFEGWRCVDRDFCANILSAESSDSEGFVIHDGECMQECPSGFIRNGSQSMYCIPCEGPCPKVCEEEKKTKTIDSVTSAQMLQGCTIFKGNLLINIRRGNNIASELENFMGLIEVVTGYVKIRHSHALVSLSFLKNLRLILGEEQLEGNYSFYVLDNQNLQQLWDWDHRNLTIKAGKMYFAFNPKLCVSEIYRMEEVTGTKGRQSKGDINTRNNGERASCESDVLHFTSTTTSKNRIIITWHRYRPPDYRDLISFTVYYKEAPFKNVTEYDGQDACGSNSWNMVDVDLPPNKDVEPGILLHGLKPWTQYAVYVKAVTLTMVENDHIRGAKSEILYIRTNASVPSIPLDVLSASNSSSQLIVKWNPPSLPNGNLSYYIVRWQRQPQDGYLYRHNYCSKDKIPIRKYADGTIDIEEVTENPKTEVCGGEKGPCCACPKTEAEKQAEKEEAEYRKVFENFLHNSIFVPRPERKRRDVMQVANTTMSSRSRNTTAADTYNITDPEELETEYPFFESRVDNKERTVISNLRPFTLYRIDIHSCNHEAEKLGCSASNFVFARTMPAEGADDIPGPVTWEPRPENSIFLKWPEPENPNGLILMYEIKYGSQVEDQRECVSRQEYRKYGGAKLNRLNPGNYTARIQATSLSGNGSWTDPVFFYVQAKTGYENFIHLIIALPVAVLLIVGGLVIMLYVFHRKRNNSRLGNGVLYASVNPEYFSAADVYVPDEWEVAREKITMSRELGQGSFGMVYEGVAKGVVKDEPETRVAIKTVNEAASMRERIEFLNEASVMKEFNCHHVVRLLGVVSQGQPTLVIMELMTRGDLKSYLRSLRPEMENNPVLAPPSLSKMIQMAGEIADGMAYLNANKFVHRDLAARNCMVAEDFTVKIGDFGMTRDIYETDYYRKGGKGLLPVRWMSPESLKDGVFTTYSDVWSFGVVLWEIATLAEQPYQGLSNEQVLRFVMEGGLLDKPDNCPDMLFELMRMCWQYNPKMRPSFLEIISSIKEEMEPGFREVSFYYSEENKLPEPEELDLEPENMESVPLDPSASSSSLPLPDRHSGHKAENGPGPGVLVLRASFDERQPYAHMNGGRKNERALPLPQSSTC", "length": 1367 }, "evidence": [ { "id": "G1K218", "url": "https://omabrowser.org/oma/group/G1K218/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "P24062-1", "protein_name": "Insulin-like growth factor 1 receptor", "gene_name": "Igf1r", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MKSGSGGGSPTSLWGLVFLSAALSLWPTSGEICGPGIDIRNDYQQLKRLENCTVIEGFLHILLISKAEDYRSYRFPKLTVITEYLLLFRVAGLESLGDLFPNLTVIRGWKLFYNYALVIFEMTNLKDIGLYNLRNITRGAIRIEKNADLCYLSTIDWSLILDAVSNNYIVGNKPPKECGDLCPGTLEEKPMCEKTTINNEYNYRCWTTNRCQKMCPSVCGKRACTENNECCHPECLGSCHTPDDNTTCVACRHYYYKGVCVPACPPGTYRFEGWRCVDRDFCANIPNAESSDSDGFVIHDGECMQECPSGFIRNSTQSMYCIPCEGPCPKVCGDEEKKTKTIDSVTSAQMLQGCTILKGNLLINIRRGNNIASELENFMGLIEVVTGYVKIRHSHALVSLSFLKNLRLILGEEQLEGNYSFYVLDNQNLQQLWDWNHRNLTVRSGKMYFAFNPKLCVSEIYRMEEVTGTKGRQSKGDINTRNNGERASCESDVLRFTSTTTWKNRIIITWHRYRPPDYRDLISFTVYYKEAPFKNVTEYDGQDACGSNSWNMVDVDLPPNKEGEPGILLHGLKPWTQYAVYVKAVTLTMVENDHIRGAKSEILYIRTNASVPSIPLDVLSASNSSSQLIVKWNPPTLPNGNLSYYIVRWQRQPQDGYLFRHNYCSKDKIPIRKYADGTIDVEEVTENPKTEVCGGDKGPCCACPKTEAEKQAEKEEAEYRKVFENFLHNSIFVPRPERRRRDVLQVANTTMSSRSRNTTVADTYNITDPEEFETEYPFFESRVDNKERTVISNLRPFTLYRIDIHSCNHEAEKLGCSASNFVFARTMPAEGADDIPGPVTWEPRPENSIFLKWPEPENPNGLILMYEIKYGSQVEDQRECVSRQEYRKYGGAKLNRLNPGNYTARIQATSLSGNGSWTDPVFFYVPAKTTYENFMHLIIALPVAILLIVGGLVIMLYVFHRKRNNSRLGNGVLYASVNPEYFSAADVYVPDEWEVAREKITMNRELGQGSFGMVYEGVAKGVVKDEPETRVAIKTVNEAASMRERIEFLNEASVMKEFNCHHVVRLLGVVSQGQPTLVIMELMTRGDLKSYLRSLRPEVENNLVLIPPSLSKMIQMAGEIADGMAYLNANKFVHRDLAARNCMVAEDFTVKIGDFGMTRDIYETDYYRKGGKGLLPVRWMSPESLKDGVFTTHSDVWSFGVVLWEIATLAEQPYQGLSNEQVLRFVMEGGLLDKPDNCPDMLFELMRMCWQYNPKMRPSFLEIIGSIKDEMEPSFQEVSFYYSEENKPPEPEELEMELELEPENMESVPLDPSASSASLPLPERHSGHKAENGPGVLVLRASFDERQPYAHMNGGRANERALPLPQSSTC", "length": 1370 }, "evidence": [ { "id": "G1K218", "url": "https://omabrowser.org/oma/group/G1K218/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "Q60751-1", "protein_name": "Insulin-like growth factor 1 receptor", "gene_name": "Igf1r", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MKSGSGGGSPTSLWGLVFLSAALSLWPTSGEICGPGIDIRNDYQQLKRLENCTVIEGFLHILLISKAEDYRSYRFPKLTVITEYLLLFRVAGLESLGDLFPNLTVIRGWKLFYNYALVIFEMTNLKDIGLYNLRNITRGAIRIEKNADLCYLSTIDWSLILDAVSNNYIVGNKPPKECGDLCPGTLEEKPMCEKTTINNEYNYRCWTTNRCQKMCPSVCGKRACTENNECCHPECLGSCHTPDDNTTCVACRHYYYKGVCVPACPPGTYRFEGWRCVDRDFCANIPNAESSDSDGFVIHDDECMQECPSGFIRNSTQSMYCIPCEGPCPKVCGDEEKKTKTIDSVTSAQMLQGCTILKGNLLINIRRGNNIASELENFMGLIEVVTGYVKIRHSHALVSLSFLKNLRLILGEEQLEGNYSFYVLDNQNLQQLWDWNHRNLTVRSGKMYFAFNPKLCVSEIYRMEEVTGTKGRQSKGDINTRNNGERASCESDVLRFTSTTTWKNRIIITWHRYRPPDYRDLISFTVYYKEAPFKNVTEYDGQDACGSNSWNMVDVDLPPNKEGEPGILLHGLKPWTQYAVYVKAVTLTMVENDHIRGAKSEILYIRTNASVPSIPLDVLSASNSSSQLIVKWNPPTLPNGNLSYYIVRWQRQPQDGYLYRHNYCSKDKIPIRKYADGTIDVEEVTENPKTEVCGGDKGPCCACPKTEAEKQAEKEEAEYRKVFENFLHNSIFVPRPERRRRDVMQVANTTMSSRSRNTTVADTYNITDPEEFETEYPFFESRVDNKERTVISNLRPFTLYRIDIHSCNHEAEKLGCSASNFVFARTMPAEGADDIPGPVTWEPRPENSIFLKWPEPENPNGLILMYEIKYGSQVEDQRECVSRQEYRKYGGAKLNRLNPGNYTARIQATSLSGNGSWTDPVFFYVPAKTTYENFMHLIIALPVAILLIVGGLVIMLYVFHRKRNNSRLGNGVLYASVNPEYFSAADVYVPDEWEVAREKITMNRELGQGSFGMVYEGVAKGVVKDEPETRVAIKTVNEAASMRERIEFLNEASVMKEFNCHHVVRLLGVVSQGQPTLVIMELMTRGDLKSYLRSLRPEVEQNNLVLIPPSLSKMIQMAGEIADGMAYLNANKFVHRDLAARNCMVAEDFTVKIGDFGMTRDIYETDYYRKGGKGLLPVRWMSPESLKDGVFTTHSDVWSFGVVLWEIATLAEQPYQGLSNEQVLRFVMEGGLLDKPDNCPDMLFELMRMCWQYNPKMRPSFLEIIGSIKDEMEPSFQEVSFYYSEENKPPEPEELEMELEMEPENMESVPLDPSASSASLPLPERHSGHKAENGPGPGVLVLRASFDERQPYAHMNGGRANERALPLPQSSTC", "length": 1373 }, "evidence": [ { "id": "G1K218", "url": "https://omabrowser.org/oma/group/G1K218/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" } ], "go_annotation": { "categories": [ { "name": "Molecular Function", "total": 7, "go_terms": [ { "name": "ATP binding", "id": "GO:0005524", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005524", "evidence": [ { "database": "UniProtKB", "id": "G1K218", "url": "https://www.uniprot.org/uniprotkb/G1K218" } ], "pmid": "" }, { "name": "insulin-like growth factor receptor activity", "id": "GO:0005010", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005010", "evidence": [ { "database": "UniProtKB", "id": "G1K218", "url": "https://www.uniprot.org/uniprotkb/G1K218" } ], "pmid": "" }, { "name": "insulin receptor substrate binding", "id": "GO:0043560", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0043560", "evidence": [ { "database": "UniProtKB", "id": "G1K218", "url": "https://www.uniprot.org/uniprotkb/G1K218" } ], "pmid": "" }, { "name": "phosphatidylinositol 3-kinase binding", "id": "GO:0043548", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0043548", "evidence": [ { "database": "UniProtKB", "id": "G1K218", "url": "https://www.uniprot.org/uniprotkb/G1K218" } ], "pmid": "" }, { "name": "insulin receptor activity", "id": "GO:0005009", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005009", "evidence": [ { "database": "UniProtKB", "id": "G1K218", "url": "https://www.uniprot.org/uniprotkb/G1K218" } ], "pmid": "" }, { "name": "insulin-like growth factor binding", "id": "GO:0005520", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005520", "evidence": [ { "database": "UniProtKB", "id": "G1K218", "url": "https://www.uniprot.org/uniprotkb/G1K218" } ], "pmid": "" }, { "name": "transmembrane receptor protein tyrosine kinase activity", "id": "GO:0004714", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0004714", "evidence": [ { "database": "UniProtKB", "id": "G1K218", "url": "https://www.uniprot.org/uniprotkb/G1K218" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 3, "go_terms": [ { "name": "plasma membrane", "id": "GO:0005886", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005886", "evidence": [ { "database": "UniProtKB", "id": "G1K218", "url": "https://www.uniprot.org/uniprotkb/G1K218" } ], "pmid": "" }, { "name": "axon", "id": "GO:0030424", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030424", "evidence": [ { "database": "UniProtKB", "id": "G1K218", "url": "https://www.uniprot.org/uniprotkb/G1K218" } ], "pmid": "" }, { "name": "insulin receptor complex", "id": "GO:0005899", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005899", "evidence": [ { "database": "UniProtKB", "id": "G1K218", "url": "https://www.uniprot.org/uniprotkb/G1K218" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 7, "go_terms": [ { "name": "positive regulation of phosphatidylinositol 3-kinase/protein kinase B signal transduction", "id": "GO:0051897", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0051897", "evidence": [ { "database": "UniProtKB", "id": "G1K218", "url": "https://www.uniprot.org/uniprotkb/G1K218" } ], "pmid": "" }, { "name": "positive regulation of MAPK cascade", "id": "GO:0043410", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0043410", "evidence": [ { "database": "UniProtKB", "id": "G1K218", "url": "https://www.uniprot.org/uniprotkb/G1K218" } ], "pmid": "" }, { "name": "cellular response to glucose stimulus", "id": "GO:0071333", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0071333", "evidence": [ { "database": "UniProtKB", "id": "G1K218", "url": "https://www.uniprot.org/uniprotkb/G1K218" } ], "pmid": "" }, { "name": "insulin receptor signaling pathway", "id": "GO:0008286", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008286", "evidence": [ { "database": "UniProtKB", "id": "G1K218", "url": "https://www.uniprot.org/uniprotkb/G1K218" } ], "pmid": "" }, { "name": "insulin-like growth factor receptor signaling pathway", "id": "GO:0048009", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0048009", "evidence": [ { "database": "UniProtKB", "id": "G1K218", "url": "https://www.uniprot.org/uniprotkb/G1K218" } ], "pmid": "" }, { "name": "regulation of JNK cascade", "id": "GO:0046328", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0046328", "evidence": [ { "database": "UniProtKB", "id": "G1K218", "url": "https://www.uniprot.org/uniprotkb/G1K218" } ], "pmid": "" }, { "name": "cell surface receptor protein tyrosine kinase signaling pathway", "id": "GO:0007169", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007169", "evidence": [ { "database": "UniProtKB", "id": "G1K218", "url": "https://www.uniprot.org/uniprotkb/G1K218" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 102, "end_pos": 104, "annotation": "n_glycosylation_sequon" }, { "start_pos": 135, "end_pos": 137, "annotation": "n_glycosylation_sequon" }, { "start_pos": 244, "end_pos": 246, "annotation": "n_glycosylation_sequon" }, { "start_pos": 314, "end_pos": 316, "annotation": "n_glycosylation_sequon" }, { "start_pos": 417, "end_pos": 419, "annotation": "n_glycosylation_sequon" }, { "start_pos": 438, "end_pos": 440, "annotation": "n_glycosylation_sequon" }, { "start_pos": 51, "end_pos": 53, "annotation": "n_glycosylation_sequon" }, { "start_pos": 534, "end_pos": 536, "annotation": "n_glycosylation_sequon" }, { "start_pos": 607, "end_pos": 609, "annotation": "n_glycosylation_sequon" }, { "start_pos": 622, "end_pos": 624, "annotation": "n_glycosylation_sequon" }, { "start_pos": 640, "end_pos": 642, "annotation": "n_glycosylation_sequon" }, { "start_pos": 747, "end_pos": 749, "annotation": "n_glycosylation_sequon" }, { "start_pos": 756, "end_pos": 758, "annotation": "n_glycosylation_sequon" }, { "start_pos": 764, "end_pos": 766, "annotation": "n_glycosylation_sequon" }, { "start_pos": 900, "end_pos": 902, "annotation": "n_glycosylation_sequon" }, { "start_pos": 913, "end_pos": 915, "annotation": "n_glycosylation_sequon" }, { "start_pos": 963, "end_pos": 965, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [ { "id": "10596", "name": "", "equation": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+)", "summary": "", "cellular_location": "", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [ "F1MWN2-1", "A0AAF6DMB3-1", "E1BI01-1", "A0AAA9TQL1-1", "F1MQH2-1", "F1N781-1", "F6QXU6-1", "A0A3Q1MKW9-1", "A0A3Q1M0U5-1", "F6S1J8-1", "A5D791-1", "F1N664-1", "E1BMP9-1", "F1MS00-1", "P43481-1", "A0A3Q1LR28-1", "A0A3Q1LVP1-1", "Q06807-1", "A0AAA9TD48-1", "Q5E9X2-1", "Q05688-1", "Q17R13-1", "E1BG90-1", "Q0VBZ0-1", "F1N758-1", "A0A3Q1LTC6-1", "A0A3Q1LNU2-1", "F1N1Q0-1", "A0A3Q1MHB0-1", "A0AAA9SN20-1", "A0AAA9TMY2-1", "A0A3Q1LI98-1", "E1BJ31-1", "A0A3Q1LRR9-1", "F1MX49-1", "A0A3Q1MHG9-1", "A0JNB0-1", "E1BER5-1", "E1BIM8-1", "E1BNE0-1", "A0A3Q1LT44-1", "A0A3Q1MJG0-1", "F1MII5-1", "F1N0D3-1", "F1N261-1", "F1N759-1", "F1N780-1", "F1MC14-1", "F1N3R6-1", "A0ABI0P1V8-1", "A0A3Q1LUE0-1", "F1MFH7-1", "F1MNW2-1", "A0AAA9SPC9-1", "F1N381-1", "F1MS29-1", "G1K218-1", "Q4TVR5-1", "A0AAA9SXH6-1", "E1BJS9-1", "A0AAA9SBR4-1", "F1MKR1-1", "F1MN51-1", "E1BCZ6-1", "E1BEL4-1", "F1MCX4-1", "F1N6J0-1", "Q3SZJ2-1", "Q769I5-1", "Z4YHD9-1", "Q06805-1", "Q3SX21-1", "A0A3Q1MAM7-1", "E1BPB5-1", "A0A3Q1MF99-1", "A0AAA9SA57-1", "A0AAA9TAT1-1", "A0AAA9THG2-1", "F1MC23-1", "A0AAA9SVL9-1", "F1MRU0-1", "A0AAA9T042-1", "E1BKP7-1", "E1BNA8-1", "F1ML02-1", "E1BPI3-1", "A0AAA9SW95-1", "G3X680-1", "A0AAA9TRY4-1", "A0A3Q1MEZ6-1", "E1B9H4-1", "E1B6X6-1", "E1B9Q2-1", "E1BPP1-1", "F1N6H6-1", "A0ABI0NRQ5-1" ], "evidence": [ { "id": "10596", "database": "Rhea", "url": "https://www.rhea-db.org/rhea/10596" } ] }, { "id": "R-BTA-2404193", "name": "IGF1R phosphorylates SHC1", "equation": "", "summary": "This event has been computationally inferred from an event that has been demonstrated in another species.

The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.

More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "cellular_location": "cytosol, plasma membrane", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [ "G1K218-1" ], "evidence": [ { "id": "R-BTA-2404193", "database": "Reactome", "url": "https://www.reactome.org/PathwayBrowser/#R-BTA-2404193" } ] }, { "id": "R-BTA-2404195", "name": "IGF1,2:p-Y1161,1165,1166-IGF1R binds SHC1", "equation": "", "summary": "This event has been computationally inferred from an event that has been demonstrated in another species.

The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.

More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "cellular_location": "plasma membrane", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [ "G1K218-1" ], "evidence": [ { "id": "R-BTA-2404195", "database": "Reactome", "url": "https://www.reactome.org/PathwayBrowser/#R-BTA-2404195" } ] }, { "id": "R-BTA-2404199", "name": "IGF1,2:IGF1R autophosphorylates", "equation": "", "summary": "This event has been computationally inferred from an event that has been demonstrated in another species.

The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.

More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "cellular_location": "cytosol, plasma membrane", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [ "G1K218-1" ], "evidence": [ { "id": "R-BTA-2404199", "database": "Reactome", "url": "https://www.reactome.org/PathwayBrowser/#R-BTA-2404199" } ] }, { "id": "R-BTA-2404200", "name": "IGF1,2 binds IGF1R", "equation": "", "summary": "This event has been computationally inferred from an event that has been demonstrated in another species.

The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.

More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "cellular_location": "extracellular region, plasma membrane", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [ "G1K218-1" ], "evidence": [ { "id": "R-BTA-2404200", "database": "Reactome", "url": "https://www.reactome.org/PathwayBrowser/#R-BTA-2404200" } ] }, { "id": "R-BTA-2428922", "name": "IGF1,2:p-Y1161,1165,1166-IGF1R binds IRS2", "equation": "", "summary": "This event has been computationally inferred from an event that has been demonstrated in another species.

The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.

More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "cellular_location": "cytosol, plasma membrane", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [ "G1K218-1" ], "evidence": [ { "id": "R-BTA-2428922", "database": "Reactome", "url": "https://www.reactome.org/PathwayBrowser/#R-BTA-2428922" } ] }, { "id": "R-BTA-2428926", "name": "IGF1,2:p-Y1161,1165,1166-IGF1R phosphorylates IRS1,2,4", "equation": "", "summary": "This event has been computationally inferred from an event that has been demonstrated in another species.

The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.

More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "cellular_location": "cytosol, plasma membrane", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [ "G1K218-1" ], "evidence": [ { "id": "R-BTA-2428926", "database": "Reactome", "url": "https://www.reactome.org/PathwayBrowser/#R-BTA-2428926" } ] }, { "id": "R-BTA-2428930", "name": "IGF1,2:p-Y1161,1165,1166-IGF1R binds IRS1,4", "equation": "", "summary": "This event has been computationally inferred from an event that has been demonstrated in another species.

The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.

More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "cellular_location": "plasma membrane", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [ "G1K218-1" ], "evidence": [ { "id": "R-BTA-2428930", "database": "Reactome", "url": "https://www.reactome.org/PathwayBrowser/#R-BTA-2428930" } ] }, { "id": "R-BTA-5686072", "name": "p-3Y-SHC1 dissociates from IGF1R", "equation": "", "summary": "This event has been computationally inferred from an event that has been demonstrated in another species.

The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.

More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "cellular_location": "cytosol, plasma membrane", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [ "G1K218-1" ], "evidence": [ { "id": "R-BTA-5686072", "database": "Reactome", "url": "https://www.reactome.org/PathwayBrowser/#R-BTA-5686072" } ] }, { "id": "R-BTA-9624272", "name": "MMPs cleave HB-EGF", "equation": "", "summary": "This event has been computationally inferred from an event that has been demonstrated in another species.

The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.

More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "cellular_location": "extracellular region, plasma membrane", "input_participant_list": [ "R-BTA-2179406" ], "output_participant_list": [ "R-BTA-1233234", "R-BTA-9624270" ], "enzyme_list": [ "F1MTX6-1", "G1K218-1", "P52176-1", "F1MKH8-1" ], "evidence": [ { "id": "R-BTA-9624272", "database": "Reactome", "url": "https://www.reactome.org/PathwayBrowser/#R-BTA-9624272" } ] }, { "id": "R-BTA-9634584", "name": "Estrogen receptor binds IGF1R and SHC1 in response to estrogen", "equation": "", "summary": "This event has been computationally inferred from an event that has been demonstrated in another species.

The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.

More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "cellular_location": "plasma membrane", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [ "G1K218-1" ], "evidence": [ { "id": "R-BTA-9634584", "database": "Reactome", "url": "https://www.reactome.org/PathwayBrowser/#R-BTA-9634584" } ] } ], "reaction_participants": [ { "participant_id": "R-BTA-1233234", "participant_name": "HBEGF [extracellular region]", "crossref": [ { "id": "XP_059744184.1", "database": "RefSeq", "url": "" }, { "id": "ENSBTAG00000021766", "database": "ENSEMBL", "url": "" }, { "id": "ENSBTAT00000029015", "database": "ENSEMBL", "url": "" }, { "id": "29765", "database": "VGNC", "url": "" }, { "id": "ENSBTAP00000029015", "database": "ENSEMBL", "url": "" }, { "id": "E1BIN8", "database": "UniProt", "url": "" }, { "id": "NP_001137562.1", "database": "RefSeq", "url": "" } ] }, { "participant_id": "R-BTA-2179406", "participant_name": "HBEGF [plasma membrane]", "crossref": [ { "id": "E1BIN8", "database": "UniProt", "url": "" }, { "id": "ENSBTAG00000021766", "database": "ENSEMBL", "url": "" }, { "id": "ENSBTAP00000029015", "database": "ENSEMBL", "url": "" }, { "id": "ENSBTAT00000029015", "database": "ENSEMBL", "url": "" }, { "id": "NP_001137562.1", "database": "RefSeq", "url": "" }, { "id": "XP_059744184.1", "database": "RefSeq", "url": "" }, { "id": "29765", "database": "VGNC", "url": "" } ] }, { "participant_id": "R-BTA-9624270", "participant_name": "HBEGF [plasma membrane]", "crossref": [ { "id": "XP_059744184.1", "database": "RefSeq", "url": "" }, { "id": "ENSBTAG00000021766", "database": "ENSEMBL", "url": "" }, { "id": "ENSBTAT00000029015", "database": "ENSEMBL", "url": "" }, { "id": "29765", "database": "VGNC", "url": "" }, { "id": "ENSBTAP00000029015", "database": "ENSEMBL", "url": "" }, { "id": "E1BIN8", "database": "UniProt", "url": "" }, { "id": "NP_001137562.1", "database": "RefSeq", "url": "" } ] } ], "reaction_enzymes": [ { "uniprot_ac": "A0A3Q1LI98", "gene_name": "ABL1", "activity": [ { "ec_number": "2.7.10.2", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A3Q1LI98", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1LI98" } ] }, { "ec_number": "2.7.10.2", "activity": "", "evidence": [ { "id": "A0A3Q1LI98", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1LI98" } ] } ] }, { "uniprot_ac": "A0A3Q1LNU2", "gene_name": "DYRK1A", "activity": [ { "ec_number": "2.7.11.23", "activity": "[DNA-directed RNA polymerase] + ATP = phospho-[DNA-directed RNA polymerase] + ADP + H(+).", "evidence": [ { "id": "A0A3Q1LNU2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1LNU2" } ] }, { "ec_number": "2.7.12.1", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A3Q1LNU2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1LNU2" } ] }, { "ec_number": "2.7.11.23", "activity": "", "evidence": [ { "id": "A0A3Q1LNU2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1LNU2" } ] }, { "ec_number": "2.7.12.1", "activity": "", "evidence": [ { "id": "A0A3Q1LNU2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1LNU2" } ] } ] }, { "uniprot_ac": "A0A3Q1LR28", "gene_name": "TESK2", "activity": [ { "ec_number": "2.7.12.1", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A3Q1LR28", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1LR28" } ] }, { "ec_number": "2.7.12.1", "activity": "", "evidence": [ { "id": "A0A3Q1LR28", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1LR28" } ] } ] }, { "uniprot_ac": "A0A3Q1LRR9", "gene_name": "TYRO3", "activity": [ { "ec_number": "2.7.10.1", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A3Q1LRR9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1LRR9" } ] }, { "ec_number": "2.7.10.1", "activity": "", "evidence": [ { "id": "A0A3Q1LRR9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1LRR9" } ] } ] }, { "uniprot_ac": "A0A3Q1LT44", "gene_name": "NTRK2", "activity": [ { "ec_number": "2.7.10.1", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A3Q1LT44", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1LT44" } ] }, { "ec_number": "2.7.10.1", "activity": "", "evidence": [ { "id": "A0A3Q1LT44", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1LT44" } ] } ] }, { "uniprot_ac": "A0A3Q1LTC6", "gene_name": "MAP2K4", "activity": [ { "ec_number": "2.7.12.2", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A3Q1LTC6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1LTC6" } ] }, { "ec_number": "2.7.12.2", "activity": "", "evidence": [ { "id": "A0A3Q1LTC6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1LTC6" } ] } ] }, { "uniprot_ac": "A0A3Q1LUE0", "gene_name": "FGFR1", "activity": [ { "ec_number": "2.7.10.1", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A3Q1LUE0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1LUE0" } ] }, { "ec_number": "2.7.10.1", "activity": "", "evidence": [ { "id": "A0A3Q1LUE0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1LUE0" } ] } ] }, { "uniprot_ac": "A0A3Q1LVP1", "gene_name": "PTK2B", "activity": [ { "ec_number": "2.7.10.2", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A3Q1LVP1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1LVP1" } ] }, { "ec_number": "2.7.10.2", "activity": "", "evidence": [ { "id": "A0A3Q1LVP1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1LVP1" } ] } ] }, { "uniprot_ac": "A0A3Q1M0U5", "gene_name": "TIE1", "activity": [ { "ec_number": "2.7.10.1", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A3Q1M0U5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1M0U5" } ] }, { "ec_number": "2.7.10.1", "activity": "", "evidence": [ { "id": "A0A3Q1M0U5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1M0U5" } ] } ] }, { "uniprot_ac": "A0A3Q1MAM7", "gene_name": "ROS1", "activity": [ { "ec_number": "2.7.10.1", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A3Q1MAM7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1MAM7" } ] }, { "ec_number": "2.7.10.1", "activity": "", "evidence": [ { "id": "A0A3Q1MAM7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1MAM7" } ] } ] }, { "uniprot_ac": "A0A3Q1MEZ6", "gene_name": "MTOR", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A3Q1MEZ6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1MEZ6" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A3Q1MEZ6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1MEZ6" } ] } ] }, { "uniprot_ac": "A0A3Q1MF99", "gene_name": "TXK", "activity": [ { "ec_number": "2.7.10.2", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A3Q1MF99", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1MF99" } ] }, { "ec_number": "2.7.10.2", "activity": "", "evidence": [ { "id": 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"activity": [ { "ec_number": "2.7.10.1", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0AAA9SN20", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9SN20" } ] }, { "ec_number": "2.7.10.1", "activity": "", "evidence": [ { "id": "A0AAA9SN20", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9SN20" } ] } ] }, { "uniprot_ac": "A0AAA9SPC9", "gene_name": "KDR", "activity": [ { "ec_number": "2.7.10.1", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0AAA9SPC9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9SPC9" } ] }, { "ec_number": "2.7.10.1", "activity": "", "evidence": [ { "id": "A0AAA9SPC9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9SPC9" } ] } ] }, { "uniprot_ac": "A0AAA9SVL9", "gene_name": "FLT4", "activity": [ { "ec_number": "2.7.10.1", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0AAA9SVL9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9SVL9" } ] }, { "ec_number": "2.7.10.1", "activity": "", "evidence": [ { "id": "A0AAA9SVL9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9SVL9" } ] } ] }, { "uniprot_ac": "A0AAA9SW95", "gene_name": "TEC", "activity": [ { "ec_number": "2.7.10.2", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0AAA9SW95", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9SW95" } ] }, { "ec_number": "2.7.10.2", "activity": "", "evidence": [ { "id": "A0AAA9SW95", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9SW95" } ] } ] }, { "uniprot_ac": "A0AAA9SXH6", "gene_name": "JAK2", "activity": [ { "ec_number": "2.7.10.2", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0AAA9SXH6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9SXH6" } ] }, { "ec_number": "2.7.10.2", "activity": "", "evidence": [ { "id": "A0AAA9SXH6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9SXH6" } ] } ] }, { "uniprot_ac": "A0AAA9T042", "gene_name": "DYRK4", "activity": [ { "ec_number": "2.7.12.1", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0AAA9T042", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9T042" } ] }, { "ec_number": "2.7.12.1", "activity": "", "evidence": [ { "id": "A0AAA9T042", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9T042" } ] } ] }, { "uniprot_ac": "A0AAA9TAT1", "gene_name": "FGFR3", "activity": [ { "ec_number": "2.7.10.1", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0AAA9TAT1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TAT1" } ] }, { "ec_number": "2.7.10.1", "activity": "", "evidence": [ { "id": "A0AAA9TAT1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TAT1" } ] } ] }, { "uniprot_ac": "A0AAA9TD48", "gene_name": "DYRK1B", "activity": [ { "ec_number": "2.7.12.1", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0AAA9TD48", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TD48" } ] }, { "ec_number": "2.7.12.1", "activity": "", "evidence": [ { "id": "A0AAA9TD48", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TD48" } ] } ] }, { "uniprot_ac": "A0AAA9THG2", "gene_name": "EPHB4", "activity": [ { "ec_number": "2.7.10.1", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0AAA9THG2", "database": "UniProtKB", "url": 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"ec_number": "2.7.10.1", "activity": "", "evidence": [ { "id": "A0AAA9TQL1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TQL1" } ] } ] }, { "uniprot_ac": "A0AAA9TRY4", "gene_name": "CSF1R", "activity": [ { "ec_number": "2.7.10.1", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0AAA9TRY4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TRY4" } ] }, { "ec_number": "2.7.10.1", "activity": "", "evidence": [ { "id": "A0AAA9TRY4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TRY4" } ] } ] }, { "uniprot_ac": "A0AAF6DMB3", "gene_name": "DDR1", "activity": [ { "ec_number": "2.7.10.1", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0AAF6DMB3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAF6DMB3" } ] }, { "ec_number": "2.7.10.1", "activity": "", "evidence": [ { "id": "A0AAF6DMB3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAF6DMB3" } ] } ] }, { "uniprot_ac": "A0ABI0NRQ5", "gene_name": "LOC101905399", "activity": [ { "ec_number": "2.7.12.2", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0ABI0NRQ5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NRQ5" } ] }, { "ec_number": "2.7.12.2", "activity": "", "evidence": [ { "id": "A0ABI0NRQ5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NRQ5" } ] } ] }, { "uniprot_ac": "A0ABI0P1V8", "gene_name": "JAK1", "activity": [ { "ec_number": "2.7.10.2", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0ABI0P1V8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0ABI0P1V8" } ] }, { "ec_number": "2.7.10.2", "activity": "", "evidence": [ { "id": "A0ABI0P1V8", "database": "UniProtKB", "url": 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"evidence": [ { "id": "E1B9H4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1B9H4" } ] } ] }, { "uniprot_ac": "E1B9Q2", "gene_name": "CLK2", "activity": [ { "ec_number": "2.7.12.1", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "E1B9Q2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1B9Q2" } ] }, { "ec_number": "2.7.12.1", "activity": "", "evidence": [ { "id": "E1B9Q2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1B9Q2" } ] } ] }, { "uniprot_ac": "E1BCZ6", "gene_name": "MST1R", "activity": [ { "ec_number": "2.7.10.1", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "E1BCZ6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BCZ6" } ] }, { "ec_number": "2.7.10.1", "activity": "", "evidence": [ { "id": "E1BCZ6", "database": "UniProtKB", "url": 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"DYRK2", "activity": [ { "ec_number": "2.7.12.1", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "E1BG90", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BG90" } ] }, { "ec_number": "2.7.12.1", "activity": "", "evidence": [ { "id": "E1BG90", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BG90" } ] } ] }, { "uniprot_ac": "E1BI01", "gene_name": "MAP2K5", "activity": [ { "ec_number": "2.7.12.2", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "E1BI01", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BI01" } ] }, { "ec_number": "2.7.12.2", "activity": "", "evidence": [ { "id": "E1BI01", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BI01" } ] } ] }, { "uniprot_ac": "E1BIM8", "gene_name": "SRC", "activity": [ { "ec_number": "2.7.10.2", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "E1BIM8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BIM8" } ] }, { "ec_number": "2.7.10.2", "activity": "", "evidence": [ { "id": "E1BIM8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BIM8" } ] } ] }, { "uniprot_ac": "E1BJ31", "gene_name": "EPHA2", "activity": [ { "ec_number": "2.7.10.1", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "E1BJ31", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BJ31" } ] }, { "ec_number": "2.7.10.1", "activity": "", "evidence": [ { "id": "E1BJ31", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BJ31" } ] } ] }, { "uniprot_ac": "E1BJS9", "gene_name": "EPHA3", "activity": [ { "ec_number": "2.7.10.1", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "E1BJS9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BJS9" } ] }, { "ec_number": "2.7.10.1", "activity": "", "evidence": [ { "id": "E1BJS9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BJS9" } ] } ] }, { "uniprot_ac": "E1BKP7", "gene_name": "MUSK", "activity": [ { "ec_number": "2.7.10.1", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "E1BKP7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BKP7" } ] }, { "ec_number": "2.7.10.1", "activity": "", "evidence": [ { "id": "E1BKP7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BKP7" } ] } ] }, { "uniprot_ac": "E1BMP9", "gene_name": "ZAP70", "activity": [ { "ec_number": "2.7.10.2", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "E1BMP9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BMP9" } ] }, { "ec_number": "2.7.10.2", "activity": "", "evidence": [ { "id": "E1BMP9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BMP9" } ] } ] }, { "uniprot_ac": "E1BNA8", "gene_name": "PTK6", "activity": [ { "ec_number": "2.7.10.2", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "E1BNA8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BNA8" } ] }, { "ec_number": "2.7.10.2", "activity": "", "evidence": [ { "id": "E1BNA8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BNA8" } ] } ] }, { "uniprot_ac": "E1BNE0", "gene_name": "FER", "activity": [ { "ec_number": "2.7.10.2", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "E1BNE0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BNE0" } ] }, { "ec_number": "2.7.10.2", "activity": "", "evidence": [ { "id": "E1BNE0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BNE0" } ] } ] }, { "uniprot_ac": "E1BPB5", "gene_name": "TESK1", "activity": [ { "ec_number": "2.7.12.1", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "E1BPB5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BPB5" } ] }, { "ec_number": "2.7.12.1", "activity": "", "evidence": [ { "id": "E1BPB5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BPB5" } ] } ] }, { "uniprot_ac": "E1BPI3", "gene_name": "FRK", "activity": [ { "ec_number": "2.7.10.2", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "E1BPI3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BPI3" } ] }, { "ec_number": "2.7.10.2", "activity": "", "evidence": [ { "id": "E1BPI3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BPI3" } ] } ] }, { "uniprot_ac": "E1BPP1", "gene_name": "TTK", "activity": [ { "ec_number": "2.7.12.1", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "E1BPP1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BPP1" } ] }, { "ec_number": "2.7.12.1", "activity": "", "evidence": [ { "id": "E1BPP1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BPP1" } ] } ] }, { "uniprot_ac": "F1MC14", "gene_name": "NTRK1", "activity": [ { "ec_number": "2.7.10.1", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "F1MC14", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MC14" } ] }, { "ec_number": "2.7.10.1", "activity": "", "evidence": [ { "id": "F1MC14", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MC14" } ] } ] }, { "uniprot_ac": "F1MC23", "gene_name": "INSRR", "activity": [ { "ec_number": "2.7.10.1", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "F1MC23", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MC23" } ] }, { "ec_number": "2.7.10.1", "activity": "", "evidence": [ { "id": "F1MC23", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MC23" } ] } ] }, { "uniprot_ac": "F1MCX4", "gene_name": "TYK2", "activity": [ { "ec_number": "2.7.10.2", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "F1MCX4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MCX4" } ] }, { "ec_number": "2.7.10.2", "activity": "", "evidence": [ { "id": "F1MCX4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MCX4" } ] } ] }, { "uniprot_ac": "F1MFH7", "gene_name": "EPHA1", "activity": [ { "ec_number": "2.7.10.1", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "F1MFH7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MFH7" } ] }, { "ec_number": "2.7.10.1", "activity": "", "evidence": [ { "id": "F1MFH7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MFH7" } ] } ] }, { "uniprot_ac": "F1MII5", "gene_name": "EPHB1", "activity": [ { "ec_number": "2.7.10.1", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "F1MII5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MII5" } ] }, { "ec_number": "2.7.10.1", "activity": "", "evidence": [ { "id": "F1MII5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MII5" } ] } ] }, { "uniprot_ac": "F1MKH8", "gene_name": "MMP2", "activity": [ { "ec_number": "3.4.24.24", "activity": "Cleavage of gelatin type I and collagen types IV, V, VII, X. Cleaves the collagen-like sequence Pro-Gln-Gly-|-Ile-Ala-Gly-Gln.", "evidence": [ { "id": "F1MKH8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MKH8" } ] }, { "ec_number": "3.4.24.24", "activity": "", "evidence": [ { "id": "F1MKH8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MKH8" } ] } ] }, { "uniprot_ac": "F1MKR1", "gene_name": "EPHA8", "activity": [ { "ec_number": "2.7.10.1", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "F1MKR1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MKR1" } ] }, { "ec_number": "2.7.10.1", "activity": "", "evidence": [ { "id": "F1MKR1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MKR1" } ] } ] }, { "uniprot_ac": "F1ML02", "gene_name": "EPHB3", "activity": [ { "ec_number": "2.7.10.1", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "F1ML02", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1ML02" } ] }, { "ec_number": "2.7.10.1", "activity": "", "evidence": [ { "id": "F1ML02", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1ML02" } ] } ] }, { "uniprot_ac": "F1MN51", "gene_name": "FGFR4", "activity": [ { "ec_number": "2.7.10.1", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "F1MN51", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MN51" } ] }, { "ec_number": "2.7.10.1", "activity": "", "evidence": [ { "id": "F1MN51", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MN51" } ] } ] }, { "uniprot_ac": "F1MNW2", "gene_name": "FGFR2", "activity": [ { "ec_number": "2.7.10.1", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "F1MNW2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MNW2" } ] }, { "ec_number": "2.7.10.1", "activity": "", "evidence": [ { "id": "F1MNW2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MNW2" } ] } ] }, { "uniprot_ac": "F1MQH2", "gene_name": "EPHA6", "activity": [ { "ec_number": "2.7.10.1", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "F1MQH2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MQH2" } ] }, { "ec_number": "2.7.10.1", "activity": "", "evidence": [ { "id": "F1MQH2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MQH2" } ] } ] }, { "uniprot_ac": "F1MRU0", "gene_name": "FLT3", "activity": [ { "ec_number": "2.7.10.1", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "F1MRU0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MRU0" } ] }, { "ec_number": "2.7.10.1", "activity": "", "evidence": [ { "id": "F1MRU0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MRU0" } ] } ] }, { "uniprot_ac": "F1MS00", "gene_name": "RET", "activity": [ { "ec_number": "2.7.10.1", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "F1MS00", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MS00" } ] }, { "ec_number": "2.7.10.1", "activity": "", "evidence": [ { "id": "F1MS00", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MS00" } ] } ] }, { "uniprot_ac": "F1MS29", "gene_name": "PTK2", "activity": [ { "ec_number": "2.7.10.2", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "F1MS29", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MS29" } ] }, { "ec_number": "2.7.10.2", "activity": "", "evidence": [ { "id": "F1MS29", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MS29" } ] } ] }, { "uniprot_ac": "F1MTX6", "gene_name": "MMP3", "activity": [ { "ec_number": "3.4.24.17", "activity": "Preferential cleavage where P1', P2' and P3' are hydrophobic residues.", "evidence": [ { "id": "F1MTX6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MTX6" } ] }, { "ec_number": "3.4.24.17", "activity": "", "evidence": [ { "id": "F1MTX6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MTX6" } ] } ] }, { "uniprot_ac": "F1MWN2", "gene_name": "HCK", "activity": [ { "ec_number": "2.7.10.2", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "F1MWN2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MWN2" } ] }, { "ec_number": "2.7.10.2", "activity": "", "evidence": [ { "id": "F1MWN2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MWN2" } ] } ] }, { "uniprot_ac": "F1MX49", "gene_name": "PDGFRA", "activity": [ { "ec_number": "2.7.10.1", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "F1MX49", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MX49" } ] }, { "ec_number": "2.7.10.1", "activity": "", "evidence": [ { "id": "F1MX49", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MX49" } ] } ] }, { "uniprot_ac": "F1N0D3", "gene_name": "AXL", "activity": [ { "ec_number": "2.7.10.1", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "F1N0D3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1N0D3" } ] }, { "ec_number": "2.7.10.1", "activity": "", "evidence": [ { "id": "F1N0D3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1N0D3" } ] } ] }, { "uniprot_ac": "F1N1Q0", "gene_name": "SRMS", "activity": [ { "ec_number": "2.7.10.2", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "F1N1Q0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1N1Q0" } ] }, { "ec_number": "2.7.10.2", "activity": "", "evidence": [ { "id": "F1N1Q0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1N1Q0" } ] } ] }, { "uniprot_ac": "F1N261", "gene_name": "LYN", "activity": [ { "ec_number": "2.7.10.2", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "F1N261", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1N261" } ] }, { "ec_number": "2.7.10.2", "activity": "", "evidence": [ { "id": "F1N261", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1N261" } ] } ] }, { "uniprot_ac": "F1N381", "gene_name": "MERTK", "activity": [ { "ec_number": "2.7.10.1", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "F1N381", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1N381" } ] }, { "ec_number": "2.7.10.1", "activity": "", "evidence": [ { "id": "F1N381", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1N381" } ] } ] }, { "uniprot_ac": "F1N3R6", "gene_name": "EPHB2", "activity": [ { "ec_number": "2.7.10.1", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "F1N3R6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1N3R6" } ] }, { "ec_number": "2.7.10.1", "activity": "", "evidence": [ { "id": "F1N3R6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1N3R6" } ] } ] }, { "uniprot_ac": "F1N664", "gene_name": "MAP2K7", "activity": [ { "ec_number": "2.7.12.2", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "F1N664", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1N664" } ] }, { "ec_number": "2.7.12.2", "activity": "", "evidence": [ { "id": "F1N664", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1N664" } ] } ] }, { "uniprot_ac": "F1N6H6", "gene_name": "EPHA10", "activity": [ { "ec_number": "2.7.10.1", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "F1N6H6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1N6H6" } ] }, { "ec_number": "2.7.10.1", "activity": "", "evidence": [ { "id": "F1N6H6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1N6H6" } ] } ] }, { "uniprot_ac": "F1N6J0", "gene_name": "NTRK3", "activity": [ { "ec_number": "2.7.10.1", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "F1N6J0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1N6J0" } ] }, { "ec_number": "2.7.10.1", "activity": "", "evidence": [ { "id": "F1N6J0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1N6J0" } ] } ] }, { "uniprot_ac": "F1N758", "gene_name": "ERBB4", "activity": [ { "ec_number": "2.7.10.1", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "F1N758", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1N758" } ] }, { "ec_number": "2.7.10.1", "activity": "", "evidence": [ { "id": "F1N758", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1N758" } ] } ] }, { "uniprot_ac": "F1N759", "gene_name": "PDGFRB", "activity": [ { "ec_number": "2.7.10.1", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "F1N759", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1N759" } ] }, { "ec_number": "2.7.10.1", "activity": "", "evidence": [ { "id": "F1N759", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1N759" } ] } ] }, { "uniprot_ac": "F1N780", "gene_name": "EPHA7", "activity": [ { "ec_number": "2.7.10.1", "activity": "L-tyrosyl-[protein] + ATP = 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"https://www.uniprot.org/uniprotkb/P13213" } ] }, { "name": "SPARC", "type": "synonym", "evidence": [ { "id": "NP_776889", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_776889" } ] } ], "protein_names": [ { "name": "SPARC", "type": "recommended", "evidence": [ { "id": "P13213", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P13213/entry#names_and_taxonomy" } ] }, { "name": "BM-40", "type": "synonym", "evidence": [ { "id": "NP_776889", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_776889" }, { "id": "P13213", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P13213/entry#names_and_taxonomy" } ] }, { "name": "Basement-membrane protein 40", "type": "synonym", "evidence": [ { "id": "P13213", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P13213/entry#names_and_taxonomy" } ] }, { "name": "ON", "type": "synonym", "evidence": [ { "id": "NP_776889", "database": "RefSeq", "url": 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"NP_776889", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_776889" } ] }, { "name": "secreted protein acidic and rich in cysteine", "type": "synonym", "evidence": [ { "id": "NP_776889", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_776889" } ] } ], "function": [ { "annotation": "Appears to regulate cell growth through interactions with the extracellular matrix and cytokines. Binds calcium and copper, several types of collagen, albumin, thrombospondin, PDGF and cell membranes. There are two calcium binding sites; an acidic domain that binds 5 to 8 Ca(2+) with a low affinity and an EF-hand loop that binds a Ca(2+) ion with a high affinity.", "evidence": [ { "database": "UniProtKB", "id": "A0A3Q1N541", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1N541#function" }, { "database": "UniProtKB", "id": "ARBA00025574", "url": "https://www.uniprot.org/uniprotkb/ARBA00025574#function" }, { "database": "UniProtKB", "id": "P13213", "url": "https://www.uniprot.org/uniprotkb/P13213#function" }, { "database": "UniProtKB", "id": "A0AAF6Z0I1", "url": "https://www.uniprot.org/uniprotkb/A0AAF6Z0I1#function" } ] }, { "annotation": "Findings indicate that secreted protein acidic cysteine-rich (SPARC) is intricately regulated by pro-angiogenic and other growth factors together with components of the extracellular matrix during the follicle-luteal transition", "evidence": [ { "database": "RefSeq", "id": "NP_776889", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_776889" }, { "database": "PubMed", "id": "22733805", "url": "https://glygen.org/publication/PubMed/22733805" } ] }, { "annotation": "This study reports the temporal changes in vascular endothelial growth factor A (VEGFA), fibroblast growth factor 2 (FGF2) and osteonectin during the follicular-luteal transition and corpus luteum development in the cow.", "evidence": [ { "database": "RefSeq", "id": "NP_776889", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_776889" }, { "database": "PubMed", "id": "17360962", "url": "https://glygen.org/publication/PubMed/17360962" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Bos taurus", "taxid": 9913, "evidence": [ { "database": "UniProtKB", "id": "P13213", "url": "https://www.uniprot.org/uniprotkb/P13213" } ], "common_name": "Bovine", "glygen_name": "Bovine", "reference_species": "Bos taurus [9913]" } ], "gene": [ { "name": "SPARC", "url": "https://www.uniprot.org/uniprotkb/P13213", "locus": { "chromosome": "7", "start_pos": 62874455, "end_pos": 62906625, "strand": "+", "evidence": [ { "database": "Ensembl Gene", "id": "ENSBTAG00000014835", "url": "https://www.ensembl.org/id/ENSBTAG00000014835" } ] } } ], "crossref": [ { "id": "P13213", "url": "https://alphafold.ebi.ac.uk/entry/P13213", "database": "AlphaFoldDB", "categories": [] }, { "id": "ENSBTAG00000014835", "url": "https://bgee.org/?page=gene&gene_id=ENSBTAG00000014835", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "cd01328", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd01328", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "cd16231", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd16231", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "282077", "url": "https://www.ncbi.nlm.nih.gov/gene/282077", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR001999", "url": "https://www.ebi.ac.uk/interpro/entry/IPR001999", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR002350", "url": "https://www.ebi.ac.uk/interpro/entry/IPR002350", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR003645", "url": "https://www.ebi.ac.uk/interpro/entry/IPR003645", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR011992", "url": "https://www.ebi.ac.uk/interpro/entry/IPR011992", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR015369", "url": "https://www.ebi.ac.uk/interpro/entry/IPR015369", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR018247", "url": "https://www.ebi.ac.uk/interpro/entry/IPR018247", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR019577", "url": "https://www.ebi.ac.uk/interpro/entry/IPR019577", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR036058", "url": "https://www.ebi.ac.uk/interpro/entry/IPR036058", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR037641", "url": "https://www.ebi.ac.uk/interpro/entry/IPR037641", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "bta:282077", "url": "https://www.genome.jp/dbget-bin/www_bget?bta:282077", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "A0A3Q1N541", "url": "https://www.orthodb.org/?gene=A0A3Q1N541", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "P13213", "url": "https://www.orthodb.org/?gene=P13213", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR13866", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR13866", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR13866:SF6", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR13866:SF6", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00050", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00050", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF09289", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF09289", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF10591", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF10591", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "R-BTA-114608", "url": "https://www.reactome.org/PathwayBrowser/#R-BTA-114608", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "R-BTA-3000497", "url": "https://www.reactome.org/PathwayBrowser/#R-BTA-3000497", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "NP_776889", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_776889", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A3Q1N541", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1N541", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A3Q1N541-1", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1N541-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0AAF6Z0I1", "url": "https://www.uniprot.org/uniprotkb/A0AAF6Z0I1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0AAF6Z0I1-1", "url": "https://www.uniprot.org/uniprotkb/A0AAF6Z0I1-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "P13213", "url": "https://www.uniprot.org/uniprotkb/P13213", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "P13213-1", "url": "https://www.uniprot.org/uniprotkb/P13213-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MRAWIFFLLCLAGRALAAPQQEALPDETEVVEETVAEVAEVPVGANPVQVEVGEFDDGAEETEEEVVAENPCQNHHCKHGKVCELDENNTPMCVCQDPTSCPAPIGEFEKVCSNDNKTFDSSCHFFATKCTLEGTKKGHKLHLDYIGPCKYIPPCLDSELTEFPLRMRDWLKNVLVTLYERDEDNNLLTEKQKLRVKKIHENEKRLEAGDHPVELLARDFEKNYNMYIFPVHWQFGQLDQHPIDGYLSHTELAPLRAPLIPMEHCTTRFFETCDLDNDKYIALDEWAGCFGIKEKDIDKDLVI", "length": 303, "header": "sp|P13213-1|SPRC_BOVIN Isoform 1 of SPARC OS=Bos taurus OX=9913 GN=SPARC PE=1 SV=2 CANONICAL=P13213-1" }, "isoforms": [ { "isoform_ac": "A0A3Q1N541-1", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1N541/entry", "sequence": { "sequence": "MTYWISPRREVPSTMRAWIFFLLCLAGRALAAPQQEALPDETEVVEETVAEVAEVPVGANPVQVEVGEFDDGAEETEEEVVAENPCQNHHCKHGKVCELDENNTPMCVCQDPTSCPAPIGEFEKVCSNDNKTFDSSCHFFATKCTLEGTKKGHKLHLDYIGPCKYIPPCLDSELTEFPLRMRDWLKNVLVTLYERDEDNNLLTEKQKLRVKKIHENEKRLEAGDHPVELLARDFEKNYNMYIFPVHWQFGQLDQHPIDGYLSHTELAPLRAPLIPMEHCTTRFFETCDLDNDKYIALDEWAGCFGIKEKDIDKDLVI", "length": 317, "header": "tr|A0A3Q1N541-1|SPRC_BOVIN Computationally mapped isoform of SPARC OS=Bos taurus OX=9913 GN=SPARC PE=1 SV=2 CANONICAL=P13213-1" }, "locus": { "chromosome": "7", "start_pos": 62906426, "end_pos": 62875639, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000075057.2", "url": "https://www.ensembl.org/id/ENSBTAT00000075057.2" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000065130.2", "url": "https://www.ensembl.org/id/ENSBTAP00000065130.2" } ] } }, { "isoform_ac": "A0AAF6Z0I1-1", "url": "https://www.uniprot.org/uniprotkb/A0AAF6Z0I1/entry", "sequence": { "sequence": "MLCHLSGEGDASTSRLPGACLLPACLPLRVPSTMRAWIFFLLCLAGRALAAPQQEALPDETEVVEETVAEVAEVPVGANPVQVEVGEFDDGAEETEEEVVAENPCQNHHCKHGKVCELDENNTPMCVCQDPTSCPAPIGEFEKVCSNDNKTFDSSCHFFATKCTLEGTKKGHKLHLDYIGPCKYIPPCLDSELTEFPLRMRDWLKNVLVTLYERDEDNNLLTEKQKLRVKKIHENEKRLEAGDHPVELLARDFEKNYNMYIFPVHWQFGQLDQHPIDGYLSHTELAPLRAPLIPMEHCTTRFFETCDLDNDKYIALDEWAGCFGIKEKDIDKDLVI", "length": 336, "header": "tr|A0AAF6Z0I1-1|A0AAF6Z0I1_BOVIN Computationally mapped isoform of SPARC OS=Bos taurus OX=9913 GN=SPARC PE=3 SV=1 CANONICAL=P13213-1" }, "locus": { "chromosome": "7", "start_pos": 62904422, "end_pos": 62875639, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000019758.7", "url": "https://www.ensembl.org/id/ENSBTAT00000019758.7" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000019758.6", "url": "https://www.ensembl.org/id/ENSBTAP00000019758.6" } ] } }, { "isoform_ac": "P13213-1", "url": "https://www.uniprot.org/uniprotkb/P13213/entry#P13213-1", "sequence": { "sequence": "MRAWIFFLLCLAGRALAAPQQEALPDETEVVEETVAEVAEVPVGANPVQVEVGEFDDGAEETEEEVVAENPCQNHHCKHGKVCELDENNTPMCVCQDPTSCPAPIGEFEKVCSNDNKTFDSSCHFFATKCTLEGTKKGHKLHLDYIGPCKYIPPCLDSELTEFPLRMRDWLKNVLVTLYERDEDNNLLTEKQKLRVKKIHENEKRLEAGDHPVELLARDFEKNYNMYIFPVHWQFGQLDQHPIDGYLSHTELAPLRAPLIPMEHCTTRFFETCDLDNDKYIALDEWAGCFGIKEKDIDKDLVI", "length": 303, "header": "sp|P13213-1|SPRC_BOVIN Isoform 1 of SPARC OS=Bos taurus OX=9913 GN=SPARC PE=1 SV=2 CANONICAL=P13213-1" }, "locus": {} } ], "glycosylation": [ { "glytoucan_ac": "", "type": "N-linked", "subtype": "other", "prediction_tool_list": [], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "N", "relation": "attached", "comment": "N-linked (GlcNAc...) asparagine", "icn3d_view": {}, "start_pos": 116, "start_aa": "Asn", "end_pos": 116, "end_aa": "Asn", "residue": "Asn", "site_lbl": "Asn116", "evidence": [ { "id": "P13213", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P13213#ptm_processing" } ], "filter_code": "001000000000000000000.00010000000000.0.01000" } ], "phosphorylation": [], "glycation": [], "keywords": [ "glycoprotein", "glycoprotein_predicted" ], "publication": [ { "title": "Characterization of 954 bovine full-CDS cDNA sequences.", "journal": "BMC Genomics", "date": "2005", "authors": "Harhay Gregory P, Sonstegard Tad S, Keele John W, Heaton Michael P, Clawson Michael L, Snelling Warren M, Wiedmann Ralph T, Van Tassell Curt P, Smith Timothy P L", "evidence": [ { "database": "UniProtKB", "id": "P13213", "url": "https://www.uniprot.org/uniprotkb/P13213" } ], "reference": [ { "type": "PubMed", "id": "16305752", "url": "https://glygen.org/publication/PubMed/16305752" } ] }, { "title": "Fibroblast growth factor 2 is more dynamic than vascular endothelial growth factor A during the follicle-luteal transition in the cow.", "journal": "Biology of reproduction", "date": "2007-07", "authors": "Robinson R S, Nicklin L T, Hammond A J, Schams D, Hunter M G, Mann G E", "evidence": [ { "database": "RefSeq", "id": "NP_776889", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_776889" } ], "reference": [ { "type": "PubMed", "id": "17360962", "url": "https://glygen.org/publication/PubMed/17360962" } ] }, { "title": "The expression, regulation and function of secreted protein, acidic, cysteine-rich in the follicle-luteal transition.", "journal": "Reproduction (Cambridge, England)", "date": "2012-09", "authors": "Joseph Chitra, Hunter Morag G, Sinclair Kevin D, Robinson Robert S", "evidence": [ { "database": "RefSeq", "id": "NP_776889", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_776889" } ], "reference": [ { "type": "PubMed", "id": "22733805", "url": "https://glygen.org/publication/PubMed/22733805" } ] }, { "title": "Osteonectin cDNA sequence reveals potential binding regions for calcium and hydroxyapatite and shows homologies with both a basement membrane protein (SPARC) and a serine proteinase inhibitor (ovomucoid).", "journal": "Proc. Natl. Acad. Sci. U.S.A.", "date": "1988", "authors": "Bolander M E, Young M F, Fisher L W, Yamada Y, Termine J D", "evidence": [ { "database": "UniProtKB", "id": "P13213", "url": "https://www.uniprot.org/uniprotkb/P13213" } ], "reference": [ { "type": "PubMed", "id": "2834720", "url": "https://glygen.org/publication/PubMed/2834720" } ] }, { "title": "Isolation of the osteonectin gene: evidence that a variable region of the osteonectin molecule is encoded within one exon.", "journal": "Biochemistry", "date": "1988", "authors": "Findlay D M, Fisher L W, McQuillan C I, Termine J D, Young M F", "evidence": [ { "database": "UniProtKB", "id": "P13213", "url": "https://www.uniprot.org/uniprotkb/P13213" } ], "reference": [ { "type": "PubMed", "id": "2835093", "url": "https://glygen.org/publication/PubMed/2835093" } ] }, { "title": "Isolation and characterization of native adult osteonectin.", "journal": "J. Biol. Chem.", "date": "1985", "authors": "Romberg R W, Werness P G, Lollar P, Riggs B L, Mann K G", "evidence": [ { "database": "UniProtKB", "id": "P13213", "url": "https://www.uniprot.org/uniprotkb/P13213" } ], "reference": [ { "type": "PubMed", "id": "2982834", "url": "https://glygen.org/publication/PubMed/2982834" } ] }, { "title": "Osteonectin mRNA: distribution in normal and transformed cells.", "journal": "Nucleic Acids Res.", "date": "1986", "authors": "Young M F, Bolander M E, Day A A, Ramis C I, Robey P G, Yamada Y, Termine J D", "evidence": [ { "database": "UniProtKB", "id": "P13213", "url": "https://www.uniprot.org/uniprotkb/P13213" } ], "reference": [ { "type": "PubMed", "id": "3012473", "url": "https://glygen.org/publication/PubMed/3012473" } ] }, { "title": "Characterization of porcine osteonectin extracted from foetal calvariae.", "journal": "Biochem. J.", "date": "1988", "authors": "Domenicucci C, Goldberg H A, Hofmann T, Isenman D, Wasi S, Sodek J", "evidence": [ { "database": "UniProtKB", "id": "P13213", "url": "https://www.uniprot.org/uniprotkb/P13213" } ], "reference": [ { "type": "PubMed", "id": "3421938", "url": "https://glygen.org/publication/PubMed/3421938" } ] } ], "pathway": [ { "id": "bta:282077", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?bta:282077", "resource": "KEGG Pathway" }, { "id": "R-BTA-114608", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-BTA-114608", "resource": "Reactome", "description": "Platelet degranulation" }, { "id": "R-BTA-3000497", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-BTA-3000497", "resource": "Reactome", "description": "Scavenging by Class H Receptors" } ], "orthologs": [ { "uniprot_canonical_ac": "A0A5G2R6P1-1", "protein_name": "SPARC", "gene_name": "SPARC", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MRAWIFFLLCLAGKALAAPQQEALPDETEVVEETVAEVPVGANPVQVEVGEFDDGAEEAEEEVVAENPCQNHHCKHGKVCELDENNSPMCVCQDPTSCPAPIGEFEKVCSNDNKTFDSSCHFFATKCTLEGTKKGHKLHLDYIGPCKYIPPCLDSELTEFPLRMRDWLKNVLVTLYERDENNNLLTEKQKLRVKKIHENEKRLEGDHPVELLARDFEKNYNMYIFPVHWQFGQLDQHPIDGYLSHTELAPLRAPLIPMEHCTTRFFQTCDLDNDKYIALDEWAGCFGIKEQDIDKDLVI", "length": 299 }, "evidence": [ { "id": "P13213", "url": "https://omabrowser.org/oma/group/P13213/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "A0A8V0YNY7-1", "protein_name": "SPARC", "gene_name": "SPARC", "tax_id": 9031, "organism": "Gallus gallus", "sequence": { "sequence": "MRTWIFFFLCLAGKALAAPQEALPDETEVIEDLTTEGPVGANPVQVEVGDESLFPRSDITPWLVPDPCQNHHCKHGKVCEVDDNNSPMCVCQDPSSCPATSGVFEKVCGTDNKTYDSSCHFFATKCTLEGTKKGHKLHLDYIGPCKFIPACLDTELTEFPLRMRDWLKNVLITLYERDEDNNLLTEKQKLKVKKIHENEKRLEAGDHTVELLARDFEKNYNMYIFPVHWQFGQLDQHPIDGYLSHTELAPLRAPLIPMEHCTTRFFEACDLDNDKYIALEEWASCFGIKEQDIDKDLVI", "length": 299 }, "evidence": [ { "id": "P13213", "url": "https://omabrowser.org/oma/group/P13213/", "database": "OMA" } ], "glygen_name": "Chicken", "common_name": "Chicken" }, { "uniprot_canonical_ac": "P07214-1", "protein_name": "SPARC", "gene_name": "Sparc", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MRAWIFFLLCLAGRALAAPQQTEVAEEIVEEETVVEETGVPVGANPVQVEMGEFEDGAEETVEEVVADNPCQNHHCKHGKVCELDESNTPMCVCQDPTSCPAPIGEFEKVCSNDNKTFDSSCHFFATKCTLEGTKKGHKLHLDYIGPCKYIAPCLDSELTEFPLRMRDWLKNVLVTLYERDEGNNLLTEKQKLRVKKIHENEKRLEAGDHPVELLARDFEKNYNMYIFPVHWQFGQLDQHPIDGYLSHTELAPLRAPLIPMEHCTTRFFETCDLDNDKYIALEEWAGCFGIKEQDINKDLVI", "length": 302 }, "evidence": [ { "id": "P13213", "url": "https://omabrowser.org/oma/group/P13213/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "P09486-1", "protein_name": "SPARC", "gene_name": "SPARC", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MRAWIFFLLCLAGRALAAPQQEALPDETEVVEETVAEVTEVSVGANPVQVEVGEFDDGAEETEEEVVAENPCQNHHCKHGKVCELDENNTPMCVCQDPTSCPAPIGEFEKVCSNDNKTFDSSCHFFATKCTLEGTKKGHKLHLDYIGPCKYIPPCLDSELTEFPLRMRDWLKNVLVTLYERDEDNNLLTEKQKLRVKKIHENEKRLEAGDHPVELLARDFEKNYNMYIFPVHWQFGQLDQHPIDGYLSHTELAPLRAPLIPMEHCTTRFFETCDLDNDKYIALDEWAGCFGIKQKDIDKDLVI", "length": 303 }, "evidence": [ { "id": "P13213", "url": "https://omabrowser.org/oma/group/P13213/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "P16975-1", "protein_name": "SPARC", "gene_name": "Sparc", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MRAWIFFLLCLAGRALAAPQTEAAEEMVAEETVVEETGLPVGANPVQVEMGEFEEGAEETVEEVVAENPCQNHHCKHGKVCELDESNTPMCVCQDPTSCPAPIGEFEKVCSNDNKTFDSSCHFFATKCTLEGTKKGHKLHLDYIGPCKYIAPCLDSELTEFPLRMRDWLKNVLVTLYERDEGNNLLTEKQKLRVKKIHENEKRLEAGDHPVELLARDFEKNYNMYIFPVHWQFGQLDQHPIDGYLSHTELAPLRAPLIPMEHCTTRFFETCDLDNDKYIALEEWAGCFGIKEQDINKDLVI", "length": 301 }, "evidence": [ { "id": "P13213", 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Acts as a regulator of Golgi membrane dynamics during the cell cycle: recruited to Golgi membrane by Rab proteins and regulates postmitotic Golgi membrane fusion (By similarity). Acts by mediating ubiquitination during mitotic Golgi disassembly, ubiquitination serving as a signal for Golgi reassembly later, after cell division. Specifically binds GTP-bound RAC1, mediating ubiquitination and subsequent degradation of active RAC1, thereby playing a role in host defense against pathogens (By similarity). May also act as a transcription regulator via its interaction with RARB (By similarity).", "evidence": [ { "database": "UniProtKB", "id": "F1N6G5", "url": "https://www.uniprot.org/uniprotkb/F1N6G5#function" }, { "database": "UniProtKB", "id": "Q3U0D9", "url": "https://www.uniprot.org/uniprotkb/Q3U0D9#function" }, { "database": "UniProtKB", "id": "Q8IYU2", "url": "https://www.uniprot.org/uniprotkb/Q8IYU2#function" } ] }, { "annotation": "E3 ubiquitin-protein ligase involved in Golgi membrane fusion and regulation of small GTPases. Acts as a regulator of Golgi membrane dynamics during the cell cycle: recruited to Golgi membrane by Rab proteins and regulates postmitotic Golgi membrane fusion. Acts by mediating ubiquitination during mitotic Golgi disassembly, ubiquitination serving as a signal for Golgi reassembly later, after cell division. 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"https://www.ebi.ac.uk/interpro/entry/IPR002110", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR035983", "url": "https://www.ebi.ac.uk/interpro/entry/IPR035983", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR036770", "url": "https://www.ebi.ac.uk/interpro/entry/IPR036770", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR050409", "url": "https://www.ebi.ac.uk/interpro/entry/IPR050409", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "bta:527565", "url": "https://www.genome.jp/dbget-bin/www_bget?bta:527565", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "QDHQDAT", "url": "https://omabrowser.org/oma/group/QDHQDAT/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "F1N6G5", "url": "https://www.orthodb.org/?gene=F1N6G5", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR11254", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR11254", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR11254:SF363", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR11254:SF363", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00023", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00023", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF00632", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00632", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF12796", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF12796", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF13637", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF13637", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF13857", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF13857", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "R-BTA-983168", "url": "https://www.reactome.org/PathwayBrowser/#R-BTA-983168", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "NP_001179574", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001179574", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A3Q1LLD9", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1LLD9", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A3Q1LLD9-1", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1LLD9-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A3Q1MAU8", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1MAU8", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A3Q1MAU8-1", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1MAU8-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A3Q1MG09", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1MG09", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A3Q1MG09-1", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1MG09-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A3Q1NMC8", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1NMC8", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A3Q1NMC8-1", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1NMC8-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0AAA9S5B4", "url": "https://www.uniprot.org/uniprotkb/A0AAA9S5B4", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0AAA9S5B4-1", "url": "https://www.uniprot.org/uniprotkb/A0AAA9S5B4-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0AAF6YIA2", "url": "https://www.uniprot.org/uniprotkb/A0AAF6YIA2", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0AAF6YIA2-1", "url": "https://www.uniprot.org/uniprotkb/A0AAF6YIA2-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "F1N6G5", "url": "https://www.uniprot.org/uniprotkb/F1N6G5", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "F1N6G5-1", "url": "https://www.uniprot.org/uniprotkb/F1N6G5-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MERAMEQLNRLTRSLRRARTVELPDDNETAVYTLMPMVMADQHRSVSELLSNSKFDVNYAFGRVKRSLLHIAANCGSVECLVLLLKKGANPNYQDISGCTPLHLAARNGQKKCMSKLLEYSADVNICNNEGLTAIHWLAVNGRTELLHDLVQHVSDVDVEDAMGQTALHVACQNGHKTTVQCLLDSGADINRPNVSGATPLYFACSHGQRDTAQILLLRGAKYLSDKNGVTPLDLCVQGGYGETCEVLIQYHPRLFQTIIQMTQNEDLRENMLRQVLEHLSQQSESQYLKILTSLAEVATTNGHKLLSISSNYDAQMKSLLRIVRIFCHVFRIGPSSPSNGIDMGYNGNKTPRSQVFKPLELLWHSLDEWLVLIATELMKNKKDSTDITSILLKQKGQDQDGTSIPPFEPPGPGSYENLSTGTGESKPDVLGGKQEASADCQDVISMTANRLSAVIQAFYMCCSCQMPPGMTSPRFIEFVCKHDEVLKCFVNRNPKIIFDHFHFLLECPELMSRFMHIIKAQPFKDRCEWFYEHLHSGQPDSDMVHRPVNENDILLVHRDSIFRSSCEVVSKANCAKLKQGIAVRFHGEEGMGQGVVREWFDILSNEIVNPDYALFTQSADGTTFQPNSNSSVNPDHLNYFRFAGQILGLALNHRQLVNIYFTRSFYKHILGIPVNYQDVASIDPEYAKNLQWILDNDISDLGLELTFSVETDVFGAMEEVPLKPGGGSILVTQNNKAEYVQLVTELRMTRAIQPQINAFLQGFHMFIPPSLIQLFDEYELELLLSGMPEIDVSDWIKNTEYTSGYEREDPVIQWFWEVVEDITPEERVLLLQFVTGSSRVPHGGFANIMGGSGLQNFTIAAVPYTPNLLPTSSTCINMLKLPEYPSKEILKDRLLVALHCGSYGYTMA", "length": 909, "header": "sp|F1N6G5-1|HACE1_BOVIN Isoform 1 of E3 ubiquitin-protein ligase HACE1 OS=Bos taurus OX=9913 GN=HACE1 PE=3 SV=3 CANONICAL=F1N6G5-1" }, "isoforms": [ { "isoform_ac": "A0A3Q1LLD9-1", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1LLD9/entry", "sequence": { "sequence": "MERAMEQLNRLTRSLRRARTVELPDDNETAVYTLMPMVMADQHRSVSELLSNSKFDVNYAFGRVKRSLLHIAANCGSVECLVLLLKKGANPNYQDISGCTPLHLAARNGQKKCMSKLLEYSADVNICNNEGLTATVQCLLDSGADINRPNVSGATPLYFACSHGQRDTAQILLLRGAKYLSDKNGVTPLDLCVQGGYGETCEVLIQYHPRLFQTIIQMTQNEDLRENMLRQVLEHLSQQSESQYLKILTSLAEVATTNGHKLLSISSNYDAQMKSLLRIVRIFCHVFRIGPSSPSNGIDMGYNGNKTPRSQVFKPLELLWHSLDEWLVLIATELMKNKKDSTDITSILLKQKGQDQDGTSIPPFEPPGPGSYENLSTGTGESKPDVLGGKQEASADCQDVISMTANRLSAVIQAFYMCCSCQMPPGMTSPRFIEFVCKHDEVLKCFVNRNPKIIFDHFHFLLECPELMSRFMHIIKAQPFKDRCEWFYEHLHSGQPDSDMVHRPVNENDILLVHRDSIFRSSCEVVSKANCAKLKQGIAVRFHGEEGMGQGVVREWFDILSNEIVNPDYALFTQSADGTTFQPNSNSSVNPDHLNYFRFAGQILGLALNHRQLVNIYFTRSFYKHILGIPVNYQDVASIDPEYAKNLQWILDNDISDLGLELTFSVETDVFGAMEEVPLKPGGGSILVTQNNKAEYVQLVTELRMTRAIQPQINAFLQGFHMFIPPSLIQLFDEYELELLLSGMPEIDVSDWIKNTEYTSGYEREDPVIQWFWEVVEDITPEERVLLLQFVTGSSRVPHGGFANIMGGSGLQNFTIAAVPYTPNLLPTSSTCINMLKLPEYPSKEILKDRLLVALHCGSYGYTMA", "length": 865, "header": "tr|A0A3Q1LLD9-1|A0A3Q1LLD9_BOVIN Computationally mapped isoform of E3 ubiquitin-protein ligase HACE1 OS=Bos taurus OX=9913 GN=HACE1 PE=4 SV=2 CANONICAL=F1N6G5-1" }, "locus": { "chromosome": "9", "start_pos": 45260347, "end_pos": 45143018, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000075225.2", "url": "https://www.ensembl.org/id/ENSBTAT00000075225.2" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000060574.2", "url": "https://www.ensembl.org/id/ENSBTAP00000060574.2" } ] } }, { "isoform_ac": "A0A3Q1MAU8-1", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1MAU8/entry", "sequence": { "sequence": "MRNPSAPVYRSVSELLSNSKFDVNYAFGRVKRSLLHIAANCGSVECLVLLLKKGANPNYQDISGCTPLHLAARNGQKKCMSKLLEYSADVNICNNEGLTAIHWLAVNGRTELLHDLVQHVSDVDVEDAMGQTALHVACQNGHKTTVQCLLDSGADINRPNVSGATPLYFACSHGQRDTAQILLLRGAKYLSDKNGVTPLDLCVQGGYGETCEVLIQYHPRLFQTIIQMTQNEDLRENMLRQVLEHLSQQSESQYLKILTSLAEVATTNGHKLLSISSNYDAQMKSLLRIVRIFCHVFRIGPSSPSNGIDMGYNGNKTPRSQVFKPLELLWHSLDEWLVLIATELMKNKKDSTDITSILLKQKGQDQDGTSIPPFEPPGPGSYENLSTGTGESKPDVLGGKQEASADCQDVISMTANRLSAVIQAFYMCCSCQMPPGMTSPRFIEFVCKHDEVLKCFVNRNPKIIFDHFHFLLECPELMSRFMHIIKAQPFKDRCEWFYEHLHSGQPDSDMVHRPVNENDILLVHRDSIFRSSCEVVSKANCAKLKQGIAVRFHGEEGMGQGVVREWFDILSNEIVNPDYALFTQSADGTTFQPNSNSSVNPDHLNYFRFAGQILGLALNHRQLVNIYFTRSFYKHILGIPVNYQDVASIDPEYAKNLQWILDNDISDLGLELTFSVETDVFGAMEEVPLKPGGGSILVTQNNKAEYVQLVTELRMTRAIQPQINAFLQGFHMFIPPSLIQLFDEYELELLLSGMPEIDVSDWIKNTEYTSGYEREDPVIQWFWEVVEDITPEERVLLLQFVTGSSRVPHGGFANIMGGSGLQNFTIAAVPYTPNLLPTSSTCINMLKLPEYPSKEILKDRLLVALHCGSYGYTMA", "length": 875, "header": "tr|A0A3Q1MAU8-1|A0A3Q1MAU8_BOVIN Computationally mapped isoform of E3 ubiquitin-protein ligase HACE1 OS=Bos taurus OX=9913 GN=HACE1 PE=4 SV=2 CANONICAL=F1N6G5-1" }, "locus": { "chromosome": "9", "start_pos": 45260347, "end_pos": 45150802, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000072969.2", "url": "https://www.ensembl.org/id/ENSBTAT00000072969.2" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000071173.2", "url": "https://www.ensembl.org/id/ENSBTAP00000071173.2" } ] } }, { "isoform_ac": "A0A3Q1MG09-1", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1MG09/entry", "sequence": { "sequence": "MERAMEQLNRLTRSLRRARTVELPDDNETAVYTLMPMVMADQHRSVSELLSNSKFDVNYAFGRVKRSLLHIAANCGSVECLVLLLKKGANPNYQDISGCTPLHLAARNGQKKCMSKLLEYSADVNICNNEGLTAIHWLAVNGRTELLHDLVQHVSDVDVEDAMGQTALHVACQNGHKTTVQCLLDSGADINRPNVSGATPLYFACSHGQRDTAQILLLRGAKYLSDKNGVTPLDLCVQGGYGETCEVLIQYHPRLFQTIIQMTQNEDLRENMLRQVLEHLSQQSESQYLKILTSLAEVATTNGHKLLSISSNYDAQMKSLLRIVRIFCHVFRIGPSSPSNGIDMGYNGNKTPRSQVFKPLELLWHSLDEWLVLIATELMKNKKDSTDITSILLKQKGQDQDGTSIPPFEPPGPGSYENLSTGTGESKPDVLGGKQEASADCQDVISMTANRLSAVIQAFYMCCSCQMPPGMTSPRFIEFVCKHDEVLKCFVNRNPKIIFDHFHFLLECPELMSRFMHIIKAQPFKDRCEWFYEHLHSGQPDSDMVHRPVNENDILLVHRDSIFRSSCEVVSKANCAKLKQGIAVRFHGEEGMGQGVVREWFDILSNEIVNPDYALFTQSADGTTFQPNSNSSVNPDHLNYFRFAGQILGLALNHRQLVNIYFTRSFYKHILGIPVNYQDVASIDPEYAKNLQWILDNDISDLGLELTFSVETDVFGAMEEVPLKPGGGSILVTQNNKAEYVQLVTELRMTRAIQPQINAFLQGFHMFIPPSLIQLFDEYELELLLSGMPEIDVSDWIKNTEYTSGYEREDPVIQWFWEVVEDITPEERVLLLQFVTGSINMLKLPEYPSKEILKDRLLVALHCGSYGYTMA", "length": 871, "header": "tr|A0A3Q1MG09-1|A0A3Q1MG09_BOVIN Computationally mapped isoform of E3 ubiquitin-protein ligase HACE1 OS=Bos taurus OX=9913 GN=HACE1 PE=4 SV=2 CANONICAL=F1N6G5-1" }, "locus": { "chromosome": "9", "start_pos": 45260347, "end_pos": 45143018, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000085626.2", "url": "https://www.ensembl.org/id/ENSBTAT00000085626.2" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000073172.2", "url": "https://www.ensembl.org/id/ENSBTAP00000073172.2" } ] } }, { "isoform_ac": "A0A3Q1NMC8-1", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1NMC8/entry", "sequence": { "sequence": "MERAMEQLNRLTRSLRRARTVELPDDNETAVYTLMPMVMADQHSCGSVECLVLLLKKGANPNYQDISGCTPLHLAARNGQKKCMSKLLEYSADVNICNNEGLTAIHWLAVNGRTELLHDLVQHVSDVDVEDAMGQTALHVACQNGHKTTVQCLLDSGADINRPNVSGATPLYFACSHGQRDTAQILLLRGAKYLSDKNGVTPLDLCVQGGYGETCEVLIQYHPRLFQTIIQMTQNEDLRENMLRQVLEHLSQQSESQYLKILTSLAEVATTNGHKLLSISSNYDAQMKSLLRIVRIFCHVFRIGPSSPSNGIDMGYNGNKTPRSQVFKPLELLWHSLDEWLVLIATELMKNKKDSTDITSILLKQKGQDQDGTSIPPFEPPGPGSYENLSTGTGESKPDVLGGKQEASADCQDVISMTANRLSAVIQAFYMCCSCQMPPGMTSPRFIEFVCKHDEVLKCFVNRNPKIIFDHFHFLLECPELMSRFMHIIKAQPFKDRCEWFYEHLHSGQPDSDMVHRPVNENDILLVHRDSIFRSSCEVVSKANCAKLKQGIAVRFHGEEGMGQGVVREWFDILSNEIVNPDYALFTQSADGTTFQPNSNSSVNPDHLNYFRFAGQILGLALNHRQLVNIYFTRSFYKHILGIPVNYQDVASIDPEYAKNLQWILDNDISDLGLELTFSVETDVFGAMEEVPLKPGGGSILVTQNNKAEYVQLVTELRMTRAIQPQINAFLQGFHMFIPPSLIQLFDEYELELLLSGMPEIDVSDWIKNTEYTSGYEREDPVIQWFWEVVEDITPEERVLLLQFVTGSSRVPHGGFANIMGGSGLQNFTIAAVPYTPNLLPTSSTCINMLKLPEYPSKEILKDRLLVALHCGSYGYTMA", "length": 879, "header": "tr|A0A3Q1NMC8-1|HACE1_BOVIN Computationally mapped isoform of E3 ubiquitin-protein ligase HACE1 OS=Bos taurus OX=9913 GN=HACE1 PE=3 SV=2 CANONICAL=F1N6G5-1" }, "locus": { "chromosome": "9", "start_pos": 45260347, "end_pos": 45143018, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000072412.2", "url": "https://www.ensembl.org/id/ENSBTAT00000072412.2" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000073740.2", "url": "https://www.ensembl.org/id/ENSBTAP00000073740.2" } ] } }, { "isoform_ac": "A0AAA9S5B4-1", "url": "https://www.uniprot.org/uniprotkb/A0AAA9S5B4/entry", "sequence": { "sequence": "MERAMEQLNRLTRSLRRARTVELPDDNETAVYTLMPMVMADQHRSVSELLSNSKFDVNYAFGRVKRSLLHIAANCGSVECLVLLLKKGANPNYQDISGCTPLHLAARNGQKKCMSKLLEYSADVNICNNEGLTAIHWLAVNGRTELLHDLVQHVSDVDVEDAMGQTALHVACQNGHKTTVQCLLDSGADINRPNVSGATPLYFACSHGQRDTAQILLLRGAKYLSDKNGVTPLDLCVQGGYGETCEVLIQYHPRLFQTIIQMTQNEDLRENMLRQVLEHLSQQSESQYLKILTSLAEVATTNGHKLLSISSNYDAQMKSLLRIVRIFCHVFRIGPSSPSNGIDMGYNGNKTPRSQVFKPLELLWHSLDEWLVLIATELMKNKKDSTDITSILLKQKGQDQDGTSIPPFEPPGPGSYENLSTGTGESKPDVLGGKQEASADCQDVISMTANRLSAVIQAFYMCCSCQMPPGMTSPRFIEFVCKHDEVLKCFVNRNPKIIFDHFHFLLECPELMSRFMHIIKAQAEYVQLVTELRMTRAIQPQINAFLQGFHMFIPPSLIQLFDEYELELLLSGMPEIDVSDWIKNTEYTSGYEREDPVIQWFWEVVEDITPEERVLLLQFVTGSSRVPHGGFANIMGGSGLQNFTIAAVPYTPNLLPTSSTCINMLKLPEYPSKEILKDRLLVALHCGSYGYTMA", "length": 694, "header": "tr|A0AAA9S5B4-1|HACE1_BOVIN Computationally mapped isoform of E3 ubiquitin-protein ligase HACE1 OS=Bos taurus OX=9913 GN=HACE1 PE=3 SV=1 CANONICAL=F1N6G5-1" }, "locus": { "chromosome": "9", "start_pos": 45260347, "end_pos": 45143018, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000115877.1", "url": "https://www.ensembl.org/id/ENSBTAT00000115877.1" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000077353.1", "url": "https://www.ensembl.org/id/ENSBTAP00000077353.1" } ] } }, { "isoform_ac": "A0AAF6YIA2-1", "url": "https://www.uniprot.org/uniprotkb/A0AAF6YIA2/entry", "sequence": { "sequence": "MERAMEQLNRLTRSLRRARTVELPDDNETAVYTLMPMVMADQHRSVSELLSNSKFDVNYAFGRVKRSLLHIAANCGSVECLVLLLKKGANPNYQDISGCTPLHLAARNGQKKCMSKLLEYSADVNICNNEGLTAIHWLAVNGRTELLHDLVQHVSDVDVEDAMGQTALHVACQNGHKTTVQCLLDSGADINRPNVSGATPLYFACSHGQRDTAQILLLRGAKYLSDKNGVTPLDLCVQGGYGETCEVLIQYHPRLFQTIIQMTQNEDLRENMLRQVLEHLSQQSESQYLKILTSLAEVATTNGHKLLSISSNYDAQMKSLLRIVRIFCHVFRIGPSSPSNGIDMGYNGNKTPRSQVFKPLELLWHSLDEWLVLIATELMKNKKDSTDITSILLKQKGQDQDGTSIPPFEPPGPGSYENLSTGTGESKPDVLGGKQEASADCQDVISMTANRLSAVIQAFYMCCSCQMPPGMTSPRFIEFVCKHDEVLKCFVNRNPKIIFDHFHFLLECPELMSRFMHIIKAQPFKDRCEWFYEHLHSGQPDSDMVHRPVNENDILLVHRDSIFRSSCEVVSKANCAKLKQGIAVRFHGEEGMGQGVVREWFDILSNEIVNPDYALFTQSADGTTFQPNSNSSVNPDHLNYFRFAGQILGLALNHRQLVNIYFTRSFYKHILGIPVNYQDVASIDPEYAKNLQWILDNDISDLGLELTFSVETDVFGAMEEVPLKPGGGSILVTQNNKAEYVQLVTELRMTRAIQPQINAFLQGFHMFIPPSLIQLFDEYELELLLSGMPEIDVSDWIKNTEYTSGYEREDPVIQFFIVVFSGSGKLWKILLQRREFFSCSLLLAVPGSHMVDLLISWVEVDCKTSQLLLCHILQIFYLLQAHASTCSSYLNTQAKKYSRTGFLWHYIVAAMVTQWHNEVWKILLTADEQFRVAEVI", "length": 936, "header": "tr|A0AAF6YIA2-1|A0AAF6YIA2_BOVIN Computationally mapped isoform of E3 ubiquitin-protein ligase HACE1 OS=Bos taurus OX=9913 GN=HACE1 PE=4 SV=1 CANONICAL=F1N6G5-1" }, "locus": { "chromosome": "9", "start_pos": 45260408, "end_pos": 45143018, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000002010.7", "url": "https://www.ensembl.org/id/ENSBTAT00000002010.7" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000002010.7", "url": "https://www.ensembl.org/id/ENSBTAP00000002010.7" } ] } }, { "isoform_ac": "F1N6G5-1", "url": "https://www.uniprot.org/uniprotkb/F1N6G5/entry#F1N6G5-1", "sequence": { "sequence": "MERAMEQLNRLTRSLRRARTVELPDDNETAVYTLMPMVMADQHRSVSELLSNSKFDVNYAFGRVKRSLLHIAANCGSVECLVLLLKKGANPNYQDISGCTPLHLAARNGQKKCMSKLLEYSADVNICNNEGLTAIHWLAVNGRTELLHDLVQHVSDVDVEDAMGQTALHVACQNGHKTTVQCLLDSGADINRPNVSGATPLYFACSHGQRDTAQILLLRGAKYLSDKNGVTPLDLCVQGGYGETCEVLIQYHPRLFQTIIQMTQNEDLRENMLRQVLEHLSQQSESQYLKILTSLAEVATTNGHKLLSISSNYDAQMKSLLRIVRIFCHVFRIGPSSPSNGIDMGYNGNKTPRSQVFKPLELLWHSLDEWLVLIATELMKNKKDSTDITSILLKQKGQDQDGTSIPPFEPPGPGSYENLSTGTGESKPDVLGGKQEASADCQDVISMTANRLSAVIQAFYMCCSCQMPPGMTSPRFIEFVCKHDEVLKCFVNRNPKIIFDHFHFLLECPELMSRFMHIIKAQPFKDRCEWFYEHLHSGQPDSDMVHRPVNENDILLVHRDSIFRSSCEVVSKANCAKLKQGIAVRFHGEEGMGQGVVREWFDILSNEIVNPDYALFTQSADGTTFQPNSNSSVNPDHLNYFRFAGQILGLALNHRQLVNIYFTRSFYKHILGIPVNYQDVASIDPEYAKNLQWILDNDISDLGLELTFSVETDVFGAMEEVPLKPGGGSILVTQNNKAEYVQLVTELRMTRAIQPQINAFLQGFHMFIPPSLIQLFDEYELELLLSGMPEIDVSDWIKNTEYTSGYEREDPVIQWFWEVVEDITPEERVLLLQFVTGSSRVPHGGFANIMGGSGLQNFTIAAVPYTPNLLPTSSTCINMLKLPEYPSKEILKDRLLVALHCGSYGYTMA", "length": 909, "header": "sp|F1N6G5-1|HACE1_BOVIN Isoform 1 of E3 ubiquitin-protein ligase HACE1 OS=Bos taurus OX=9913 GN=HACE1 PE=3 SV=3 CANONICAL=F1N6G5-1" }, "locus": {} } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [ "enzyme" ], "publication": [ { "title": "A whole-genome assembly of the domestic cow, Bos taurus.", "journal": "Genome Biol.", "date": "2009", "authors": "Zimin Aleksey V, Delcher Arthur L, Florea Liliana, Kelley David R, Schatz Michael C, Puiu Daniela, Hanrahan Finnian, Pertea Geo, Van Tassell Curtis P, Sonstegard Tad S, Mar\u00e7ais Guillaume, Roberts Michael, Subramanian Poorani, Yorke James A, Salzberg Steven L", "evidence": [ { "database": "UniProtKB", "id": "F1N6G5", "url": "https://www.uniprot.org/uniprotkb/F1N6G5" } ], "reference": [ { "type": "PubMed", "id": "19393038", "url": "https://glygen.org/publication/PubMed/19393038" } ] } ], "pathway": [ { "id": "bta:527565", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?bta:527565", "resource": "KEGG Pathway" }, { "id": "R-BTA-983168", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-BTA-983168", "resource": "Reactome", "description": "Antigen processing: Ubiquitination & Proteasome degradation" } ], "orthologs": [ { "uniprot_canonical_ac": "D3ZBM7-1", "protein_name": "E3 ubiquitin-protein ligase HACE1", "gene_name": "Hace1", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MERAMEQLNRLTRSLRRARTVELPEDNETAVYTLMPMVMADQHRSVSELLSNSKFDVNYAFGRVKRSLLHIAANCGSVECLVLLLKKGANPNYQDISGCTPLHLAARNGQKKCMSKLLEYSADVNICNNEGLTAIHWLAVNGRTELLHDLVQHVTDVDVEDAMGQTALHVACQNGHKTTVQCLLDSGADINRPNVAGATPLYFACSHGQRDTAQILLLRGAKYLPDKNGVTPLDLCVQGGYGQTCEVLIQYHPRLFQTIVQMTQNEDLRENMLRQVLQHLSQQSESQYLKILTGLAEVATTNGHKLLSLSSSYEAQMKSLLRIVRIFCHVFRIGPSSPSNGMDMGYNGNKTPRSQVFKPLELLWHSLDEWLVLIATELMKNKEDSADITSILLKQKGQDQEASCISAFEPPGPGSYERLSTGPGESKPDVLAGKQEASADCQDVISVTANRLSAVIQAFYMCCSCQMPPGMTSPRFIEFVCKHDEVLKCFVNRNPKIIFDHFHFLLECPELMSRFMHIIKAQPFKDRCEWFYEHLHSGQPDSDMVHRPVSENDILLVHRDSIFRSSCEIVSKANCAKLKQGIAVRFHGEEGMGQGVVREWFDILSNEIVNPDYALFTQSADGTTFQPNSNSYVNPDHLNYFRFAGQILGLALNHRQLVNIYFTRSFYKHILGIPVNYQDVASIDPEYAKNLQWILDNDISDLGLELTFSVETDVFGAMEEVPLKPGGGSILVTQNNKAEYVQLVTELRMTRAIQPQINAFLQGFHMFIPPSLIQLFDEYELELLLSGMPEIDVNDWIKNTEYTSGYEREDPVIQWFWEVVEDMTQEERVLLLQFVTGSSRVPHGGFANIMGGSGLQNFTIAAVPYTPNLLPTSSTCINMLKLPEYPSKEILKDRLLVALHCGSYGYTMA", "length": 909 }, "evidence": [ { "id": "F1N6G5", "url": "https://omabrowser.org/oma/group/F1N6G5/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "E1C656-1", "protein_name": "E3 ubiquitin-protein ligase HACE1", "gene_name": "HACE1", "tax_id": 9031, "organism": "Gallus gallus", "sequence": { "sequence": "MERAMEQLNRLTRSLRRARTVELPDDNETAVYTLMPMVMADQHRSVSELLSNSKFDVNYAFGRVKRSLLHIAANCGSVECLVLLLKKGANPNYQDISGCTPLHLAARNGQKKCMSKLLEYSADVNICNNEGLTAIHWLAVNGRTELLHDLVQHVSNVDVEDAMGQTALHVACQNGHKTTVQCLLDSGADINRPNVSGATPLYFACSHGQRDTAQILLMRGAKYLPDKNGITPLDLCVQGGYGETCEVLIQYHPRLFQTIIQMTQNEDLRENMLRQVLEHLSQQSESQYLKILTSLAEVATTNGHKLLSLSSNYEAQMKSLLRIVRIFCHVFRIGPSSPSNGNDMGYNGNKTPRSQVFKVRKVYDVVRKIDVKEMNFTKHAFINQTSHEQEPLELLWHSLDEWLVLIATELMKNKRDSANITSILLKQKGPDHQDATPTPSFAAAGTESRKELSTDTGDSKTYEVAGKQEAYADCQDVISMTANRLSAVIQAFYMCCSCQMPQGMTSPRFIEFVCKHDDVLKCFVNRNPKIIFDHFHFLLECPELMSRFMHIIKAQPFKDRCEWFYEHLHSGQPDSDMVHRPVNENDILLVHRDSIFRSSCEVVSKANCAKLKQGIAVRFHGEEGMGQGVVREWFDILSSEIVNPDYALFTQSADGTTFQPNSNSSVNPDHLNYFRFAGQILGLALNHRQLVNIYFTRSFYKHILGIPVNYQDVASIDPEYAKNLQWILDNDISDLGLELTFSVETDVFGAMEEVPLKPGGASILVTQENKAEYVQLVTELRMTRAIQPQINAFLQGFHMFIPPSLIQLFDEYELELLLSGMPEIDVNDWLKNTEYTSGYERGDQVIQWFWDVVEELTQEERVLLLQFVTGSSRVPHGGFAHIMGGSGLQNFTIAAVPYTANLLPTSSTCINMLKLPEYPSKEILKDRLLVALHCGSYGYTMA", "length": 942 }, "evidence": [ { "id": "F1N6G5", "url": "https://omabrowser.org/oma/group/F1N6G5/", "database": "OMA" } ], "glygen_name": "Chicken", "common_name": "Chicken" }, { "uniprot_canonical_ac": "F8W2M1-1", "protein_name": "E3 ubiquitin-protein ligase HACE1", "gene_name": "hace1", "tax_id": 7955, "organism": "Danio rerio", "sequence": { "sequence": "MERAMEHLNVQLNRLTRSLRRARTVELPEDSETAVYTLMPMVMADQHRSVSELLLNSKFDVNYAFGRVKRSLLHIAANCGSVECLVLLLKRGANPNYQDISGCTPLHLAARNGQKKCMGRLLEYNADVNICNNEGLTAIHWLAVNGRTELLHDLVQHVTNVDVEDAMGQTALHVACQNGHKTTVQCLLDSGADINRPNVSGATPLYFACSHGQRDTAQILLLRGAKYLPDRNGVTPLDLCVQGGYGETCEILIQHHGRLFQTLIQMTQNDDIKENMLRQVLEHVSQQNDSNYQRILTSLAEVATTNGHKLLSLSSNFEVQTKSLLRIIRIFCHVFCLGPSSPNNGNDMGYNGNKTPRSQVFKPLELLWHSLDEWLVLISTELEKEITDTTRSSSGNDIASLFLKKQEVDHSVSSENPQLLLDASSVMKTPEVYADGQDVISMIANRLSAVIQAFYMCCSCQMPHGMTSPRFIEFVCKHDEVLKCFVTRNPKIIFNHFHFLLECPELMSRFMHIIKGQPFKDRCEWFYEHLLAGQPDSDMVHRPVNENDILLVHRDSLFRSSCEVVSKSSNEKLKQGIAVRFHGEEGMGQGVVREWFDILSNEIINPDYALFTQSADGTTFQPNSNSSVNPDHLNYFRFAGQILGLALYHRQLVNIYFTRSFYKHILGIPVSYQDVSSIDPEYAKNLQWILDNDISDLGLELTFSVETDVFGTMEEVPLKPGGTTIQVTQDNKEEYVQLVTELRMTRAIQPQINAFLQGFHTFIPPSLIQLFDEYELELLLSGMPEIDVMDWKRNTEYTSGYDLQEPVIQWFWEVVENLTQEERVLLLQFVTGSSRVPHGGFAFLMGGSGLQKFTVAAVPYTSNLLPTSSTCINMLKLPEYPSKDVLRDRLLVALHCGSYGYTMA", "length": 904 }, "evidence": [ { "id": "F1N6G5", "url": "https://omabrowser.org/oma/group/F1N6G5/", "database": "OMA" } ], "glygen_name": "Zebrafish", "common_name": "Zebrafish" }, { "uniprot_canonical_ac": "Q3U0D9-1", "protein_name": "E3 ubiquitin-protein ligase HACE1", "gene_name": "Hace1", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MERAMEQLNRLTRSLRRARTVELPEDNETAVYTLMPMVMADQHRSVSELLSNSKFDVNYAFGRVKRSLLHIAANCGSVECLVLLLKKGANPNYQDISGCTPLHLAARNGQKKCMSKLLEYSADVNICNNEGLTAIHWLAVNGRTELLHDLVQHVTDVDVEDAMGQTALHVACQNGHKTTVQCLLDSGADINRPNVSGATPLYFACSHGQRDTAQILLLRGAKYLPDKNGVTPLDLCVQGGYGQTCEVLIQYHPRLFQTIVQMTQNEDLRENMLRQVLQHLSQQSESQYLKILTGLAEVATTNGHKLLSLSSNYDAQMKSLLRIVRIFCHVFRIGPSSPSNGIDMGYNGNKTPRSQVFKPLELLWHSLDEWLVLIATELMKNKEDSTDITSILLKQKGQDQEAPSLSAFEPPGPGSYESLPPGPGDSKPEVLAGEQEASADCQDVISVTANRLSAVIQAFYMCCSCQMPPGMTSPRFIEFVCKHDEVLKCFVNRNPKIIFDHFHFLLECPELMSRFMHIIKAQPFKDRCEWFYEHLHSGQPDSDMVHRPVSENDILLVHRDSIFRSSCEIVSKANCAKLKQGIAVRFHGEEGMGQGVVREWFDILSNEIVNPDYALFTQSADGTTFQPNSNSYVNPDHLNYFRFAGQILGLALNHRQLVNIYFTRSFYKHILGIPVNYQDVASIDPEYAKNLQWILDNDISDLGLELTFSVETDVFGAMEEVPLKPGGGSILVTQNNKAEYVQLVTELRMTRAIQPQINAFLQGFHMFIPPSLIQLFDEYELELLLSGMPEIDVNDWIKNTEYTSGYEREDPVIQWFWEVVEDITQEERVLLLQFVTGSSRVPHGGFANIMGGSGLQNFTIAAVPYTPNLLPTSSTCINMLKLPEYPSKEILKDRLLVALHCGSYGYTMA", "length": 909 }, "evidence": [ { "id": "F1N6G5", "url": "https://omabrowser.org/oma/group/F1N6G5/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" } ], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 5, "go_terms": [ { "name": "Golgi membrane", "id": "GO:0000139", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000139", "evidence": [ { "database": "UniProtKB", "id": "F1N6G5", "url": "https://www.uniprot.org/uniprotkb/F1N6G5" } ], "pmid": "" }, { "name": "nucleus", "id": "GO:0005634", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005634", "evidence": [ { "database": "UniProtKB", "id": "F1N6G5", "url": "https://www.uniprot.org/uniprotkb/F1N6G5" } ], "pmid": "" }, { "name": "cytoplasm", "id": "GO:0005737", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005737", "evidence": [ { "database": "UniProtKB", "id": "F1N6G5", "url": "https://www.uniprot.org/uniprotkb/F1N6G5" } ], "pmid": "" }, { "name": "endoplasmic reticulum", "id": "GO:0005783", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005783", "evidence": [ { "database": "UniProtKB", "id": "F1N6G5", "url": "https://www.uniprot.org/uniprotkb/F1N6G5" } ], "pmid": "" }, { "name": "Golgi cisterna membrane", "id": "GO:0032580", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0032580", "evidence": [ { "database": "UniProtKB", "id": "F1N6G5", "url": "https://www.uniprot.org/uniprotkb/F1N6G5" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 7, "go_terms": [ { "name": "DNA-templated transcription", "id": "GO:0006351", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006351", "evidence": [ { "database": "UniProtKB", "id": "F1N6G5", "url": "https://www.uniprot.org/uniprotkb/F1N6G5" } ], "pmid": "" }, { "name": "protein ubiquitination", "id": "GO:0016567", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016567", "evidence": [ { "database": "UniProtKB", "id": "F1N6G5", "url": "https://www.uniprot.org/uniprotkb/F1N6G5" } ], "pmid": "" }, { "name": "regulation of cell migration", "id": "GO:0030334", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030334", "evidence": [ { "database": "UniProtKB", "id": "F1N6G5", "url": "https://www.uniprot.org/uniprotkb/F1N6G5" } ], "pmid": "" }, { "name": "membrane fusion", "id": "GO:0061025", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0061025", "evidence": [ { "database": "UniProtKB", "id": "F1N6G5", "url": "https://www.uniprot.org/uniprotkb/F1N6G5" } ], "pmid": "" }, { "name": "ubiquitin-dependent protein catabolic process", "id": "GO:0006511", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006511", "evidence": [ { "database": "UniProtKB", "id": "F1N6G5", "url": "https://www.uniprot.org/uniprotkb/F1N6G5" } ], "pmid": "" }, { "name": "protein K48-linked ubiquitination", "id": "GO:0070936", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0070936", "evidence": [ { "database": "UniProtKB", "id": "F1N6G5", "url": "https://www.uniprot.org/uniprotkb/F1N6G5" } ], "pmid": "" }, { "name": "Golgi organization", "id": "GO:0007030", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007030", "evidence": [ { "database": "UniProtKB", "id": "F1N6G5", "url": "https://www.uniprot.org/uniprotkb/F1N6G5" } ], "pmid": "" } ] }, { "name": "Molecular Function", "total": 3, "go_terms": [ { "name": "ubiquitin protein ligase activity", "id": "GO:0061630", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0061630", "evidence": [ { "database": "UniProtKB", "id": "F1N6G5", "url": "https://www.uniprot.org/uniprotkb/F1N6G5" } ], "pmid": "" }, { "name": "small GTPase binding", "id": "GO:0031267", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0031267", "evidence": [ { "database": "UniProtKB", "id": "F1N6G5", "url": "https://www.uniprot.org/uniprotkb/F1N6G5" } ], "pmid": "" }, { "name": "ubiquitin-protein transferase activity", "id": "GO:0004842", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0004842", "evidence": [ { "database": "UniProtKB", "id": "F1N6G5", "url": "https://www.uniprot.org/uniprotkb/F1N6G5" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 194, "end_pos": 196, "annotation": "n_glycosylation_sequon" }, { "start_pos": 27, "end_pos": 29, "annotation": "n_glycosylation_sequon" }, { "start_pos": 349, "end_pos": 351, "annotation": "n_glycosylation_sequon" }, { "start_pos": 418, "end_pos": 420, "annotation": "n_glycosylation_sequon" }, { "start_pos": 630, "end_pos": 632, "annotation": "n_glycosylation_sequon" }, { "start_pos": 857, "end_pos": 859, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [ { "id": "R-BTA-983140", "name": "Transfer of Ub from E2 to substrate and release of E2", "equation": "", "summary": "This event has been computationally inferred from an event that has been demonstrated in another species.

The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.

More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "cellular_location": "cytosol", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [ "P61085-1", "A1A4I9-1", "E1BJS7-1", "A3KN22-1", "A6H795-1", "E1B7Q7-1", "E1BH71-1", "F1MM41-1", "Q32PA5-1", "Q3MHP1-1", "Q5E9J6-1", "Q7YRV4-1", "A0A3Q1N3G7-1", "A5PJC4-1", "A0AAF6DMH9-1", "E1BCU1-1", "F1MJS5-1", "F1MYL0-1", "F1N6G5-1", "Q0P5K3-1", "Q17QG5-1", "Q1JQA1-1", "Q1RMW1-1", "Q1RMX2-1", "Q29RQ5-1", "Q2T9X7-1", "Q2TA03-1", "Q2TA10-1", "Q32LN1-1", "Q32LN5-1", "Q32P99-1", "F1MEX6-1", "F1MTS8-1", "F1N495-1", "F1N645-1", "Q0II22-1", "Q1RML1-1", "A0JN74-1", "A5PKG6-1", "E1B782-1", "E1B7G3-1", "E1B8R6-1", "E1BCW1-1", "E1BIW0-1", "E1BNY9-1", "F1MBM6-1", "A0A3Q1MLB6-1", "A0A3Q1MLH2-1", "E1BAV2-1", "F1N1X8-1", "F1N3I3-1", "F1N5G3-1", "A0AAA9TKS8-1", "F1N703-1", "F1N7A0-1", "A0AAA9TWH7-1", "A0A3Q1LV49-1", "A0AAA9S100-1", "A0AAA9RZ14-1", "F1MLS5-1", "F1MWS4-1", "A5D7F8-1", "F1MJ10-1", "A0A3Q1MAR8-1", "A0AAA9RXI4-1", "Q4U5R4-1", "Q32L27-1", "E1B7D3-1", "E1BBN5-1", "E1BBY2-1", "A0AAA9RXX2-1", "E1BID7-1", "A0ABI0NWC8-1", "E1BIP5-1", "E1BL26-1", "E1BNQ6-1" ], "evidence": [ { "id": "R-BTA-983140", "database": "Reactome", "url": "https://www.reactome.org/PathwayBrowser/#R-BTA-983140" } ] }, { "id": "R-BTA-983147", "name": "Release of E3 from polyubiquitinated substrate", "equation": "", "summary": "This event has been computationally inferred from an event that has been demonstrated in another species.

The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.

More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "cellular_location": "cytosol", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [ "A1A4I9-1", "E1BJS7-1", "E1B7Q7-1", "E1BH71-1", "F1MM41-1", "Q5E9J6-1", "Q7YRV4-1", "A0A3Q1N3G7-1", "A0AAF6DMH9-1", "E1BCU1-1", "F1MJS5-1", "F1MYL0-1", "F1N6G5-1", "Q1JQA1-1", "Q29RQ5-1", "Q32LN5-1", "F1MEX6-1", "F1MTS8-1", "F1N495-1", "F1N645-1", "Q0II22-1", "A0JN74-1", "A5PKG6-1", "E1B782-1", "E1B7G3-1", "E1B8R6-1", "E1BCW1-1", "E1BIW0-1", "E1BNY9-1", "F1MBM6-1", "A0A3Q1MLH2-1", "E1BAV2-1", "F1N5G3-1", "A0AAA9TKS8-1", "F1N703-1", "F1N7A0-1", "A0AAA9TWH7-1", "A0A3Q1LV49-1", "A0AAA9S100-1", "A0AAA9RZ14-1", "F1MLS5-1", "F1MWS4-1", "A5D7F8-1", "F1MJ10-1", "A0AAA9RXI4-1", "Q4U5R4-1", "E1B7D3-1", "E1BBN5-1", "E1BBY2-1", "A0AAA9RXX2-1", "E1BID7-1", "E1BIP5-1", "E1BL26-1", "E1BNQ6-1" ], "evidence": [ { "id": "R-BTA-983147", "database": "Reactome", "url": "https://www.reactome.org/PathwayBrowser/#R-BTA-983147" } ] }, { "id": "R-BTA-983156", "name": "Polyubiquitination of substrate", "equation": "", "summary": "This event has been computationally inferred from an event that has been demonstrated in another species.

The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.

More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "cellular_location": "cytosol", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [ "P61085-1", "A1A4I9-1", "E1BJS7-1", "A3KN22-1", "A6H795-1", "E1B7Q7-1", "E1BH71-1", "F1MM41-1", "Q32PA5-1", "Q3MHP1-1", "Q5E9J6-1", "Q7YRV4-1", "A0A3Q1N3G7-1", "A5PJC4-1", "A0AAF6DMH9-1", "E1BCU1-1", "F1MJS5-1", "F1MYL0-1", "F1N6G5-1", "Q0P5K3-1", "Q17QG5-1", "Q1JQA1-1", "Q1RMW1-1", "Q1RMX2-1", "Q29RQ5-1", "Q2T9X7-1", "Q2TA03-1", "Q2TA10-1", "Q32LN1-1", "Q32LN5-1", "Q32P99-1", "F1MEX6-1", "F1MTS8-1", "F1N495-1", "F1N645-1", "Q0II22-1", "Q1RML1-1", "A0JN74-1", "A5PKG6-1", "E1B782-1", "E1B7G3-1", "E1B8R6-1", "E1BCW1-1", "E1BIW0-1", "E1BNY9-1", "F1MBM6-1", "A0A3Q1MLB6-1", "A0A3Q1MLH2-1", "E1BAV2-1", "F1N1X8-1", "F1N3I3-1", "F1N5G3-1", "A0AAA9TKS8-1", "F1N703-1", "F1N7A0-1", "A0AAA9TWH7-1", "A0A3Q1LV49-1", "A0AAA9S100-1", "A0AAA9RZ14-1", "F1MLS5-1", "F1MWS4-1", "A5D7F8-1", "F1MJ10-1", "A0A3Q1MAR8-1", "A0AAA9RXI4-1", "Q4U5R4-1", "Q32L27-1", "E1B7D3-1", "E1BBN5-1", "E1BBY2-1", "A0AAA9RXX2-1", "E1BID7-1", "A0ABI0NWC8-1", "E1BIP5-1", "E1BL26-1", "E1BNQ6-1" ], "evidence": [ { "id": "R-BTA-983156", "database": "Reactome", "url": "https://www.reactome.org/PathwayBrowser/#R-BTA-983156" } ] }, { "id": "R-BTA-983157", "name": "Interaction of E3 with substrate and E2-Ub complex", "equation": "", "summary": "This event has been computationally inferred from an event that has been demonstrated in another species.

The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.

More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "cellular_location": "cytosol", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [ "P61085-1", "A1A4I9-1", "E1BJS7-1", "A3KN22-1", "A6H795-1", "E1B7Q7-1", "E1BH71-1", "F1MM41-1", "Q32PA5-1", "Q3MHP1-1", "Q5E9J6-1", "Q7YRV4-1", "A0A3Q1N3G7-1", "A5PJC4-1", "A0AAF6DMH9-1", "E1BCU1-1", "F1MJS5-1", "F1MYL0-1", "F1N6G5-1", "Q0P5K3-1", "Q17QG5-1", "Q1JQA1-1", "Q1RMW1-1", "Q1RMX2-1", "Q29RQ5-1", "Q2T9X7-1", "Q2TA03-1", "Q2TA10-1", "Q32LN1-1", "Q32LN5-1", "Q32P99-1", "F1MEX6-1", "F1MTS8-1", "F1N495-1", "F1N645-1", "Q0II22-1", "Q1RML1-1", "A0JN74-1", "A5PKG6-1", "E1B782-1", "E1B7G3-1", "E1B8R6-1", "E1BCW1-1", "E1BIW0-1", "E1BNY9-1", "F1MBM6-1", "A0A3Q1MLB6-1", "A0A3Q1MLH2-1", "E1BAV2-1", "F1N1X8-1", "F1N3I3-1", "F1N5G3-1", "A0AAA9TKS8-1", "F1N703-1", "F1N7A0-1", "A0AAA9TWH7-1", "A0A3Q1LV49-1", "A0AAA9S100-1", "A0AAA9RZ14-1", "F1MLS5-1", "F1MWS4-1", "A5D7F8-1", "F1MJ10-1", "A0A3Q1MAR8-1", "A0AAA9RXI4-1", "Q4U5R4-1", "Q32L27-1", "E1B7D3-1", "E1BBN5-1", "E1BBY2-1", "A0AAA9RXX2-1", "E1BID7-1", "A0ABI0NWC8-1", "E1BIP5-1", "E1BL26-1", "E1BNQ6-1" ], "evidence": [ { "id": "R-BTA-983157", "database": "Reactome", "url": "https://www.reactome.org/PathwayBrowser/#R-BTA-983157" } ] } ], "reaction_participants": [], "reaction_enzymes": [ { "uniprot_ac": "A0A3Q1LV49", "gene_name": "LOC512869", "activity": [ { "ec_number": "2.3.2.27", "activity": "S-ubiquitinyl-[E2 ubiquitin-conjugating enzyme]-L-cysteine + [acceptor protein]-L-lysine = [E2 ubiquitin-conjugating enzyme]-L-cysteine + N(6)-ubiquitinyl-[acceptor protein]-L-lysine.", "evidence": [ { "id": "A0A3Q1LV49", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1LV49" } ] }, { "ec_number": "2.3.2.27", "activity": "", "evidence": [ { "id": "A0A3Q1LV49", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1LV49" } ] } ] }, { "uniprot_ac": "A0A3Q1MAR8", "gene_name": "UBE2E1", "activity": [ { "ec_number": "2.3.2.23", "activity": "S-ubiquitinyl-[E1 ubiquitin-activating enzyme]-L-cysteine + [E2 ubiquitin-conjugating enzyme]-L-cysteine = [E1 ubiquitin-activating enzyme]-L-cysteine + S-ubiquitinyl-[E2 ubiquitin-conjugating enzyme]-L-cysteine.", "evidence": [ { "id": "A0A3Q1MAR8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1MAR8" } ] }, { "ec_number": "2.3.2.23", "activity": "", "evidence": [ { "id": "A0A3Q1MAR8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1MAR8" } ] } ] }, { "uniprot_ac": "A0A3Q1MLB6", "gene_name": "UBE2R2", "activity": [ { "ec_number": "2.3.2.23", "activity": "S-ubiquitinyl-[E1 ubiquitin-activating enzyme]-L-cysteine + [E2 ubiquitin-conjugating enzyme]-L-cysteine = [E1 ubiquitin-activating enzyme]-L-cysteine + S-ubiquitinyl-[E2 ubiquitin-conjugating enzyme]-L-cysteine.", "evidence": [ { "id": "A0A3Q1MLB6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1MLB6" } ] }, { "ec_number": "2.3.2.23", "activity": "", "evidence": [ { "id": "A0A3Q1MLB6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1MLB6" } ] } ] }, { "uniprot_ac": "A0A3Q1MLH2", "gene_name": "RNF144B", "activity": [ { "ec_number": "2.3.2.31", "activity": "[E2 ubiquitin-conjugating enzyme]-S-ubiquitinyl-L-cysteine + [acceptor protein]-L-lysine = [E2 ubiquitin-conjugating enzyme]-L-cysteine + [acceptor protein]-N(6)-ubiquitinyl-L-lysine.", "evidence": [ { "id": "A0A3Q1MLH2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1MLH2" } ] }, { "ec_number": "2.3.2.31", "activity": "", "evidence": [ { "id": "A0A3Q1MLH2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1MLH2" } ] } ] }, { "uniprot_ac": "A0A3Q1N3G7", "gene_name": "TRIM36", "activity": [ { "ec_number": "2.3.2.27", "activity": "S-ubiquitinyl-[E2 ubiquitin-conjugating enzyme]-L-cysteine + [acceptor protein]-L-lysine = [E2 ubiquitin-conjugating enzyme]-L-cysteine + N(6)-ubiquitinyl-[acceptor protein]-L-lysine.", "evidence": [ { "id": "A0A3Q1N3G7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1N3G7" } ] }, { "ec_number": "2.3.2.27", "activity": "", "evidence": [ { "id": "A0A3Q1N3G7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1N3G7" } ] } ] }, { "uniprot_ac": "A0AAA9RXI4", "gene_name": "MGRN1", "activity": [ { "ec_number": "2.3.2.27", "activity": "S-ubiquitinyl-[E2 ubiquitin-conjugating enzyme]-L-cysteine + [acceptor protein]-L-lysine = [E2 ubiquitin-conjugating enzyme]-L-cysteine + N(6)-ubiquitinyl-[acceptor protein]-L-lysine.", "evidence": [ { "id": "A0AAA9RXI4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9RXI4" } ] }, { "ec_number": "2.3.2.27", "activity": "", "evidence": [ { "id": "A0AAA9RXI4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9RXI4" } ] } ] }, { "uniprot_ac": "A0AAA9RXX2", "gene_name": "RBBP6", "activity": [ { "ec_number": "2.3.2.27", "activity": "S-ubiquitinyl-[E2 ubiquitin-conjugating enzyme]-L-cysteine + [acceptor protein]-L-lysine = [E2 ubiquitin-conjugating enzyme]-L-cysteine + N(6)-ubiquitinyl-[acceptor protein]-L-lysine.", "evidence": [ { "id": "A0AAA9RXX2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9RXX2" } ] }, { "ec_number": "2.3.2.27", "activity": "", "evidence": [ { "id": "A0AAA9RXX2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9RXX2" } ] } ] }, { "uniprot_ac": "A0AAA9RZ14", "gene_name": "ITCH", "activity": [ { "ec_number": "2.3.2.26", "activity": "S-ubiquitinyl-[E2 ubiquitin-conjugating enzyme]-L-cysteine + [acceptor protein]-L-lysine = [E2 ubiquitin-conjugating enzyme]-L-cysteine + N(6)-ubiquitinyl-[acceptor protein]-L-lysine.", "evidence": [ { "id": "A0AAA9RZ14", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9RZ14" } ] }, { "ec_number": "2.3.2.26", "activity": "", "evidence": [ { "id": "A0AAA9RZ14", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9RZ14" } ] } ] }, { "uniprot_ac": "A0AAA9S100", "gene_name": "MKRN1", "activity": [ { "ec_number": "2.3.2.27", "activity": "S-ubiquitinyl-[E2 ubiquitin-conjugating enzyme]-L-cysteine + [acceptor protein]-L-lysine = [E2 ubiquitin-conjugating enzyme]-L-cysteine + N(6)-ubiquitinyl-[acceptor protein]-L-lysine.", "evidence": [ { "id": "A0AAA9S100", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9S100" } ] }, { "ec_number": "2.3.2.27", "activity": "", "evidence": [ { "id": "A0AAA9S100", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9S100" } ] } ] }, { "uniprot_ac": "A0AAA9TKS8", "gene_name": "RNF217", "activity": [ { "ec_number": "2.3.2.31", "activity": "[E2 ubiquitin-conjugating enzyme]-S-ubiquitinyl-L-cysteine + [acceptor protein]-L-lysine = [E2 ubiquitin-conjugating enzyme]-L-cysteine + [acceptor protein]-N(6)-ubiquitinyl-L-lysine.", "evidence": [ { "id": "A0AAA9TKS8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TKS8" } ] }, { "ec_number": "2.3.2.31", "activity": "", "evidence": [ { "id": "A0AAA9TKS8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TKS8" } ] } ] }, { "uniprot_ac": "A0AAA9TWH7", "gene_name": "SMURF2", "activity": [ { "ec_number": "2.3.2.26", "activity": "S-ubiquitinyl-[E2 ubiquitin-conjugating enzyme]-L-cysteine + [acceptor protein]-L-lysine = [E2 ubiquitin-conjugating enzyme]-L-cysteine + N(6)-ubiquitinyl-[acceptor protein]-L-lysine.", "evidence": [ { "id": "A0AAA9TWH7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TWH7" } ] }, { "ec_number": "2.3.2.26", "activity": "", "evidence": [ { "id": "A0AAA9TWH7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TWH7" } ] } ] }, { "uniprot_ac": "A0AAF6DMH9", "gene_name": "RNF130", "activity": [ { "ec_number": "2.3.2.27", "activity": "S-ubiquitinyl-[E2 ubiquitin-conjugating enzyme]-L-cysteine + [acceptor protein]-L-lysine = [E2 ubiquitin-conjugating enzyme]-L-cysteine + N(6)-ubiquitinyl-[acceptor protein]-L-lysine.", "evidence": [ { "id": "A0AAF6DMH9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAF6DMH9" } ] }, { "ec_number": "2.3.2.27", "activity": "", "evidence": [ { "id": "A0AAF6DMH9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAF6DMH9" } ] } ] }, { "uniprot_ac": "A0ABI0NWC8", "gene_name": "UBE2Q1", "activity": [ { "ec_number": "2.3.2.23", "activity": "S-ubiquitinyl-[E1 ubiquitin-activating enzyme]-L-cysteine + [E2 ubiquitin-conjugating enzyme]-L-cysteine = [E1 ubiquitin-activating enzyme]-L-cysteine + S-ubiquitinyl-[E2 ubiquitin-conjugating enzyme]-L-cysteine.", "evidence": [ { "id": "A0ABI0NWC8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NWC8" } ] }, { "ec_number": "2.3.2.23", "activity": "", "evidence": [ { "id": "A0ABI0NWC8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NWC8" } ] } ] }, { "uniprot_ac": "A0JN74", "gene_name": "TRIM11", "activity": [ { "ec_number": "2.3.2.27", "activity": "S-ubiquitinyl-[E2 ubiquitin-conjugating enzyme]-L-cysteine + [acceptor protein]-L-lysine = [E2 ubiquitin-conjugating enzyme]-L-cysteine + N(6)-ubiquitinyl-[acceptor protein]-L-lysine.", "evidence": [ { "id": "A0JN74", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0JN74" } ] }, { "ec_number": "2.3.2.27", "activity": "", "evidence": [ { "id": "A0JN74", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0JN74" } ] } ] }, { "uniprot_ac": "A1A4I9", "gene_name": "UFL1", "activity": [ { "ec_number": "2.3.2.-", "activity": "", "evidence": [ { "id": "A1A4I9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A1A4I9" } ] } ] }, { "uniprot_ac": "A3KN22", "gene_name": "UBE2M", "activity": [ { "ec_number": "2.3.2.34", "activity": "[E1 NEDD8-activating enzyme]-S-[NEDD8 protein]-yl-L-cysteine + [E2 NEDD8-conjugating enzyme]-L-cysteine = [E1 NEDD8-activating enzyme]-L-cysteine + [E2 NEDD8-conjugating enzyme]-S-[NEDD8-protein]-yl-L-cysteine.", "evidence": [ { "id": "A3KN22", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A3KN22" } ] }, { "ec_number": "2.3.2.34", "activity": "", "evidence": [ { "id": "A3KN22", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A3KN22" } ] } ] }, { "uniprot_ac": "A5D7F8", "gene_name": "SH3RF1", "activity": [ { "ec_number": "2.3.2.27", "activity": "S-ubiquitinyl-[E2 ubiquitin-conjugating enzyme]-L-cysteine + [acceptor protein]-L-lysine = [E2 ubiquitin-conjugating enzyme]-L-cysteine + N(6)-ubiquitinyl-[acceptor protein]-L-lysine.", "evidence": [ { "id": "A5D7F8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A5D7F8" } ] }, { "ec_number": "2.3.2.27", "activity": "", "evidence": [ { "id": "A5D7F8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A5D7F8" } ] } ] }, { "uniprot_ac": "A5PJC4", "gene_name": "UBE2L6", "activity": [ { "ec_number": "2.3.2.23", "activity": "S-ubiquitinyl-[E1 ubiquitin-activating enzyme]-L-cysteine + [E2 ubiquitin-conjugating enzyme]-L-cysteine = [E1 ubiquitin-activating enzyme]-L-cysteine + S-ubiquitinyl-[E2 ubiquitin-conjugating enzyme]-L-cysteine.", "evidence": [ { "id": "A5PJC4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A5PJC4" } ] }, { "ec_number": "2.3.2.23", "activity": "", "evidence": [ { "id": "A5PJC4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A5PJC4" } ] } ] }, { "uniprot_ac": "A5PKG6", "gene_name": "UBE4A", "activity": [ { "ec_number": "2.3.2.27", "activity": "S-ubiquitinyl-[E2 ubiquitin-conjugating enzyme]-L-cysteine + [acceptor protein]-L-lysine = [E2 ubiquitin-conjugating enzyme]-L-cysteine + N(6)-ubiquitinyl-[acceptor protein]-L-lysine.", "evidence": [ { "id": "A5PKG6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A5PKG6" } ] }, { "ec_number": "2.3.2.27", "activity": "", "evidence": [ { "id": "A5PKG6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A5PKG6" } ] } ] }, { "uniprot_ac": "A6H795", "gene_name": "UBE2W", "activity": [ { "ec_number": "2.3.2.25", "activity": "S-ubiquitinyl-[E1 ubiquitin-activating enzyme]-L-cysteine + [acceptor protein]-N-terminal-amino acid = [E1 ubiquitin-activating enzyme]-L-cysteine + N-terminal-ubiquitinyl-[acceptor protein].", "evidence": [ { "id": "A6H795", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A6H795" } ] }, { "ec_number": "2.3.2.23", "activity": "S-ubiquitinyl-[E1 ubiquitin-activating enzyme]-L-cysteine + [E2 ubiquitin-conjugating enzyme]-L-cysteine = [E1 ubiquitin-activating enzyme]-L-cysteine + S-ubiquitinyl-[E2 ubiquitin-conjugating enzyme]-L-cysteine.", "evidence": [ { "id": "A6H795", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A6H795" } ] }, { "ec_number": "2.3.2.23", "activity": "", "evidence": [ { "id": "A6H795", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A6H795" } ] } ] }, { "uniprot_ac": "E1B782", "gene_name": "HERC2", "activity": [ { "ec_number": "2.3.2.26", "activity": "S-ubiquitinyl-[E2 ubiquitin-conjugating enzyme]-L-cysteine + [acceptor protein]-L-lysine = [E2 ubiquitin-conjugating enzyme]-L-cysteine + N(6)-ubiquitinyl-[acceptor protein]-L-lysine.", "evidence": [ { "id": "E1B782", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1B782" } ] }, { "ec_number": "2.3.2.26", "activity": "", "evidence": [ { "id": "E1B782", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1B782" } ] } ] }, { "uniprot_ac": "E1B7D3", "gene_name": "TRIM39", "activity": [ { "ec_number": "2.3.2.27", "activity": "S-ubiquitinyl-[E2 ubiquitin-conjugating enzyme]-L-cysteine + [acceptor protein]-L-lysine = [E2 ubiquitin-conjugating enzyme]-L-cysteine + N(6)-ubiquitinyl-[acceptor protein]-L-lysine.", "evidence": [ { "id": "E1B7D3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1B7D3" } ] }, { "ec_number": "2.3.2.27", "activity": "", "evidence": [ { "id": "E1B7D3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1B7D3" } ] } ] }, { "uniprot_ac": "E1B7G3", "gene_name": "STUB1", "activity": [ { "ec_number": "2.3.2.27", "activity": "S-ubiquitinyl-[E2 ubiquitin-conjugating enzyme]-L-cysteine + [acceptor protein]-L-lysine = [E2 ubiquitin-conjugating enzyme]-L-cysteine + N(6)-ubiquitinyl-[acceptor protein]-L-lysine.", "evidence": [ { "id": "E1B7G3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1B7G3" } ] }, { "ec_number": "2.3.2.27", "activity": "", "evidence": [ { "id": "E1B7G3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1B7G3" } ] } ] }, { "uniprot_ac": "E1B7Q7", "gene_name": "TRIP12", "activity": [ { "ec_number": "2.3.2.26", "activity": "S-ubiquitinyl-[E2 ubiquitin-conjugating enzyme]-L-cysteine + [acceptor protein]-L-lysine = [E2 ubiquitin-conjugating enzyme]-L-cysteine + N(6)-ubiquitinyl-[acceptor protein]-L-lysine.", "evidence": [ { "id": "E1B7Q7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1B7Q7" } ] }, { "ec_number": "2.3.2.26", "activity": "", "evidence": [ { "id": "E1B7Q7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1B7Q7" } ] } ] }, { "uniprot_ac": "E1B8R6", "gene_name": "ARIH2", "activity": [ { "ec_number": "2.3.2.31", "activity": "[E2 ubiquitin-conjugating enzyme]-S-ubiquitinyl-L-cysteine + [acceptor protein]-L-lysine = [E2 ubiquitin-conjugating enzyme]-L-cysteine + [acceptor protein]-N(6)-ubiquitinyl-L-lysine.", "evidence": [ { "id": "E1B8R6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1B8R6" } ] }, { "ec_number": "2.3.2.31", "activity": "", "evidence": [ { "id": "E1B8R6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1B8R6" } ] } ] }, { "uniprot_ac": "E1BAV2", "gene_name": "HERC4", "activity": [ { "ec_number": "2.3.2.26", "activity": "S-ubiquitinyl-[E2 ubiquitin-conjugating enzyme]-L-cysteine + [acceptor protein]-L-lysine = [E2 ubiquitin-conjugating enzyme]-L-cysteine + N(6)-ubiquitinyl-[acceptor protein]-L-lysine.", "evidence": [ { "id": "E1BAV2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BAV2" } ] }, { "ec_number": "2.3.2.26", "activity": "", "evidence": [ { "id": "E1BAV2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BAV2" } ] } ] }, { "uniprot_ac": "E1BBN5", "gene_name": "MIB2", "activity": [ { "ec_number": "2.3.2.27", "activity": "S-ubiquitinyl-[E2 ubiquitin-conjugating enzyme]-L-cysteine + [acceptor protein]-L-lysine = [E2 ubiquitin-conjugating enzyme]-L-cysteine + N(6)-ubiquitinyl-[acceptor protein]-L-lysine.", "evidence": [ { "id": "E1BBN5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BBN5" } ] }, { "ec_number": "2.3.2.27", "activity": "", "evidence": [ { "id": "E1BBN5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BBN5" } ] } ] }, { "uniprot_ac": "E1BBY2", "gene_name": "TRIM41", "activity": [ { "ec_number": "2.3.2.27", "activity": "S-ubiquitinyl-[E2 ubiquitin-conjugating enzyme]-L-cysteine + [acceptor protein]-L-lysine = [E2 ubiquitin-conjugating enzyme]-L-cysteine + N(6)-ubiquitinyl-[acceptor protein]-L-lysine.", "evidence": [ { "id": "E1BBY2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BBY2" } ] }, { "ec_number": "2.3.2.27", "activity": "", "evidence": [ { "id": "E1BBY2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BBY2" } ] } ] }, { "uniprot_ac": "E1BCU1", "gene_name": "UBE3B", "activity": [ { "ec_number": "2.3.2.26", "activity": "S-ubiquitinyl-[E2 ubiquitin-conjugating enzyme]-L-cysteine + [acceptor protein]-L-lysine = [E2 ubiquitin-conjugating enzyme]-L-cysteine + N(6)-ubiquitinyl-[acceptor protein]-L-lysine.", "evidence": [ { "id": "E1BCU1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BCU1" } ] }, { "ec_number": "2.3.2.26", "activity": "", "evidence": [ { "id": "E1BCU1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BCU1" } ] } ] }, { "uniprot_ac": "E1BCW1", "gene_name": "UBR2", "activity": [ { "ec_number": "2.3.2.27", "activity": "S-ubiquitinyl-[E2 ubiquitin-conjugating enzyme]-L-cysteine + [acceptor protein]-L-lysine = [E2 ubiquitin-conjugating enzyme]-L-cysteine + N(6)-ubiquitinyl-[acceptor protein]-L-lysine.", "evidence": [ { "id": "E1BCW1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BCW1" } ] }, { "ec_number": "2.3.2.27", "activity": "", "evidence": [ { "id": "E1BCW1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BCW1" } ] } ] }, { "uniprot_ac": "E1BH71", "gene_name": "DTX3L", "activity": [ { "ec_number": "2.3.2.27", "activity": "S-ubiquitinyl-[E2 ubiquitin-conjugating enzyme]-L-cysteine + [acceptor protein]-L-lysine = [E2 ubiquitin-conjugating enzyme]-L-cysteine + N(6)-ubiquitinyl-[acceptor protein]-L-lysine.", "evidence": [ { "id": "E1BH71", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BH71" } ] }, { "ec_number": "2.3.2.27", "activity": "", "evidence": [ { "id": "E1BH71", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BH71" } ] } ] }, { "uniprot_ac": "E1BID7", "gene_name": "TRIM69", "activity": [ { "ec_number": "2.3.2.27", "activity": "S-ubiquitinyl-[E2 ubiquitin-conjugating enzyme]-L-cysteine + [acceptor protein]-L-lysine = [E2 ubiquitin-conjugating enzyme]-L-cysteine + N(6)-ubiquitinyl-[acceptor protein]-L-lysine.", "evidence": [ { "id": "E1BID7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BID7" } ] }, { "ec_number": "2.3.2.27", "activity": "", "evidence": [ { "id": "E1BID7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BID7" } ] } ] }, { "uniprot_ac": "E1BIP5", "gene_name": "RNF19A", "activity": [ { "ec_number": "2.3.2.31", "activity": "[E2 ubiquitin-conjugating enzyme]-S-ubiquitinyl-L-cysteine + [acceptor protein]-L-lysine = [E2 ubiquitin-conjugating enzyme]-L-cysteine + [acceptor protein]-N(6)-ubiquitinyl-L-lysine.", "evidence": [ { "id": "E1BIP5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BIP5" } ] }, { "ec_number": "2.3.2.31", "activity": "", "evidence": [ { "id": "E1BIP5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BIP5" } ] } ] }, { "uniprot_ac": "E1BIW0", "gene_name": "UBR1", "activity": [ { "ec_number": "2.3.2.27", "activity": "S-ubiquitinyl-[E2 ubiquitin-conjugating enzyme]-L-cysteine + [acceptor protein]-L-lysine = [E2 ubiquitin-conjugating enzyme]-L-cysteine + N(6)-ubiquitinyl-[acceptor protein]-L-lysine.", "evidence": [ { "id": "E1BIW0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BIW0" } ] }, { "ec_number": "2.3.2.27", "activity": "", "evidence": [ { "id": "E1BIW0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BIW0" } ] } ] }, { "uniprot_ac": "E1BJS7", "gene_name": "TRIM71", "activity": [ { "ec_number": "2.3.2.27", "activity": "S-ubiquitinyl-[E2 ubiquitin-conjugating enzyme]-L-cysteine + [acceptor protein]-L-lysine = [E2 ubiquitin-conjugating enzyme]-L-cysteine + N(6)-ubiquitinyl-[acceptor protein]-L-lysine.", "evidence": [ { "id": "E1BJS7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BJS7" } ] }, { "ec_number": "2.3.2.27", "activity": "", "evidence": [ { "id": "E1BJS7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BJS7" } ] } ] }, { "uniprot_ac": "E1BL26", "gene_name": "RNF123", "activity": [ { "ec_number": "2.3.2.27", "activity": "S-ubiquitinyl-[E2 ubiquitin-conjugating enzyme]-L-cysteine + [acceptor protein]-L-lysine = [E2 ubiquitin-conjugating enzyme]-L-cysteine + N(6)-ubiquitinyl-[acceptor protein]-L-lysine.", "evidence": [ { "id": "E1BL26", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BL26" } ] }, { "ec_number": "2.3.2.27", "activity": "", "evidence": [ { "id": "E1BL26", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BL26" } ] } ] }, { "uniprot_ac": "E1BNQ6", "gene_name": "TRIM50", "activity": [ { "ec_number": "2.3.2.27", "activity": "S-ubiquitinyl-[E2 ubiquitin-conjugating enzyme]-L-cysteine + [acceptor protein]-L-lysine = [E2 ubiquitin-conjugating enzyme]-L-cysteine + N(6)-ubiquitinyl-[acceptor protein]-L-lysine.", "evidence": [ { "id": "E1BNQ6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BNQ6" } ] }, { "ec_number": "2.3.2.27", "activity": "", "evidence": [ { "id": "E1BNQ6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BNQ6" } ] } ] }, { "uniprot_ac": "E1BNY9", "gene_name": "HUWE1", "activity": [ { "ec_number": "2.3.2.26", "activity": "S-ubiquitinyl-[E2 ubiquitin-conjugating enzyme]-L-cysteine + [acceptor protein]-L-lysine = [E2 ubiquitin-conjugating enzyme]-L-cysteine + N(6)-ubiquitinyl-[acceptor protein]-L-lysine.", "evidence": [ { "id": "E1BNY9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BNY9" } ] }, { "ec_number": "2.3.2.26", "activity": "", "evidence": [ { "id": "E1BNY9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BNY9" } ] } ] }, { "uniprot_ac": "F1MBM6", "gene_name": "SIAH2", "activity": [ { "ec_number": "2.3.2.27", "activity": "S-ubiquitinyl-[E2 ubiquitin-conjugating enzyme]-L-cysteine + [acceptor protein]-L-lysine = [E2 ubiquitin-conjugating enzyme]-L-cysteine + N(6)-ubiquitinyl-[acceptor protein]-L-lysine.", "evidence": [ { "id": "F1MBM6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MBM6" } ] }, { "ec_number": "2.3.2.27", "activity": "", "evidence": [ { "id": "F1MBM6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MBM6" } ] } ] }, { "uniprot_ac": "F1MEX6", "gene_name": "RNF19B", "activity": [ { "ec_number": "2.3.2.31", "activity": "[E2 ubiquitin-conjugating enzyme]-S-ubiquitinyl-L-cysteine + [acceptor protein]-L-lysine = [E2 ubiquitin-conjugating enzyme]-L-cysteine + [acceptor protein]-N(6)-ubiquitinyl-L-lysine.", "evidence": [ { "id": "F1MEX6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MEX6" } ] }, { "ec_number": "2.3.2.31", "activity": "", "evidence": [ { "id": "F1MEX6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MEX6" } ] } ] }, { "uniprot_ac": "F1MJ10", "gene_name": "NEDD4", "activity": [ { "ec_number": "2.3.2.26", "activity": "S-ubiquitinyl-[E2 ubiquitin-conjugating enzyme]-L-cysteine + [acceptor protein]-L-lysine = [E2 ubiquitin-conjugating enzyme]-L-cysteine + N(6)-ubiquitinyl-[acceptor protein]-L-lysine.", "evidence": [ { "id": "F1MJ10", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MJ10" } ] }, { "ec_number": "2.3.2.26", "activity": "", "evidence": [ { "id": "F1MJ10", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MJ10" } ] } ] }, { "uniprot_ac": "F1MJS5", "gene_name": "HECTD3", "activity": [ { "ec_number": "2.3.2.26", "activity": "S-ubiquitinyl-[E2 ubiquitin-conjugating enzyme]-L-cysteine + [acceptor protein]-L-lysine = [E2 ubiquitin-conjugating enzyme]-L-cysteine + N(6)-ubiquitinyl-[acceptor protein]-L-lysine.", "evidence": [ { "id": "F1MJS5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MJS5" } ] }, { "ec_number": "2.3.2.26", "activity": "", "evidence": [ { "id": "F1MJS5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MJS5" } ] } ] }, { "uniprot_ac": "F1MLS5", "gene_name": "SMURF1", "activity": [ { "ec_number": "2.3.2.26", "activity": "S-ubiquitinyl-[E2 ubiquitin-conjugating enzyme]-L-cysteine + [acceptor protein]-L-lysine = [E2 ubiquitin-conjugating enzyme]-L-cysteine + N(6)-ubiquitinyl-[acceptor protein]-L-lysine.", "evidence": [ { "id": "F1MLS5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MLS5" } ] }, { "ec_number": "2.3.2.26", "activity": "", "evidence": [ { "id": "F1MLS5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MLS5" } ] } ] }, { "uniprot_ac": "F1MM41", "gene_name": "ZNRF1", "activity": [ { "ec_number": "2.3.2.27", "activity": "S-ubiquitinyl-[E2 ubiquitin-conjugating enzyme]-L-cysteine + [acceptor protein]-L-lysine = [E2 ubiquitin-conjugating enzyme]-L-cysteine + N(6)-ubiquitinyl-[acceptor protein]-L-lysine.", "evidence": [ { "id": "F1MM41", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MM41" } ] }, { "ec_number": "2.3.2.27", "activity": "", "evidence": [ { "id": "F1MM41", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MM41" } ] } ] }, { "uniprot_ac": "F1MTS8", "gene_name": "LTN1", "activity": [ { "ec_number": "2.3.2.27", "activity": "S-ubiquitinyl-[E2 ubiquitin-conjugating enzyme]-L-cysteine + [acceptor protein]-L-lysine = [E2 ubiquitin-conjugating enzyme]-L-cysteine + N(6)-ubiquitinyl-[acceptor protein]-L-lysine.", "evidence": [ { "id": "F1MTS8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MTS8" } ] }, { "ec_number": "2.3.2.27", "activity": "", "evidence": [ { "id": "F1MTS8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MTS8" } ] } ] }, { "uniprot_ac": "F1MWS4", "gene_name": "RNF25", "activity": [ { "ec_number": "2.3.2.27", "activity": "S-ubiquitinyl-[E2 ubiquitin-conjugating enzyme]-L-cysteine + [acceptor protein]-L-lysine = [E2 ubiquitin-conjugating enzyme]-L-cysteine + N(6)-ubiquitinyl-[acceptor protein]-L-lysine.", "evidence": [ { "id": "F1MWS4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MWS4" } ] }, { "ec_number": "2.3.2.27", "activity": "", "evidence": [ { "id": "F1MWS4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MWS4" } ] } ] }, { "uniprot_ac": "F1MYL0", "gene_name": "RNF220", "activity": [ { "ec_number": "2.3.2.27", "activity": "S-ubiquitinyl-[E2 ubiquitin-conjugating enzyme]-L-cysteine + [acceptor protein]-L-lysine = [E2 ubiquitin-conjugating enzyme]-L-cysteine + N(6)-ubiquitinyl-[acceptor protein]-L-lysine.", "evidence": [ { "id": "F1MYL0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MYL0" } ] }, { "ec_number": "2.3.2.27", "activity": "", "evidence": [ { "id": "F1MYL0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MYL0" } ] } ] }, { "uniprot_ac": "F1N1X8", "gene_name": "UBE2Z", "activity": [ { "ec_number": "2.3.2.23", "activity": "S-ubiquitinyl-[E1 ubiquitin-activating enzyme]-L-cysteine + [E2 ubiquitin-conjugating enzyme]-L-cysteine = [E1 ubiquitin-activating enzyme]-L-cysteine + S-ubiquitinyl-[E2 ubiquitin-conjugating enzyme]-L-cysteine.", "evidence": [ { "id": "F1N1X8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1N1X8" } ] }, { "ec_number": "2.3.2.23", "activity": "", "evidence": [ { "id": "F1N1X8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1N1X8" } ] } ] }, { "uniprot_ac": "F1N3I3", "gene_name": "UBE2O", "activity": [ { "ec_number": "2.3.2.24", "activity": "S-ubiquitinyl-[E1 ubiquitin-activating enzyme]-L-cysteine + [acceptor protein]-L-lysine = [E1 ubiquitin-activating enzyme]-L-cysteine + N(6)-monoubiquitinyl-[acceptor protein]-L-lysine.", "evidence": [ { "id": "F1N3I3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1N3I3" } ] }, { "ec_number": "2.3.2.24", "activity": "", "evidence": [ { "id": "F1N3I3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1N3I3" } ] } ] }, { "uniprot_ac": "F1N495", "gene_name": "AREL1", "activity": [ { "ec_number": "2.3.2.26", "activity": "S-ubiquitinyl-[E2 ubiquitin-conjugating enzyme]-L-cysteine + [acceptor protein]-L-lysine = [E2 ubiquitin-conjugating enzyme]-L-cysteine + N(6)-ubiquitinyl-[acceptor protein]-L-lysine.", "evidence": [ { "id": "F1N495", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1N495" } ] }, { "ec_number": "2.3.2.26", "activity": "", "evidence": [ { "id": "F1N495", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1N495" } ] } ] }, { "uniprot_ac": "F1N5G3", "gene_name": "SIAH1", "activity": [ { "ec_number": "2.3.2.27", "activity": "S-ubiquitinyl-[E2 ubiquitin-conjugating enzyme]-L-cysteine + [acceptor protein]-L-lysine = [E2 ubiquitin-conjugating enzyme]-L-cysteine + N(6)-ubiquitinyl-[acceptor protein]-L-lysine.", "evidence": [ { "id": "F1N5G3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1N5G3" } ] }, { "ec_number": "2.3.2.27", "activity": "", "evidence": [ { "id": "F1N5G3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1N5G3" } ] } ] }, { "uniprot_ac": "F1N645", "gene_name": "HECW2", "activity": [ { "ec_number": "2.3.2.26", "activity": "S-ubiquitinyl-[E2 ubiquitin-conjugating enzyme]-L-cysteine + [acceptor protein]-L-lysine = [E2 ubiquitin-conjugating enzyme]-L-cysteine + N(6)-ubiquitinyl-[acceptor protein]-L-lysine.", "evidence": [ { "id": "F1N645", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1N645" } ] }, { "ec_number": "2.3.2.26", "activity": "", "evidence": [ { "id": "F1N645", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1N645" } ] } ] }, { "uniprot_ac": "F1N6G5", "gene_name": "HACE1", "activity": [ { "ec_number": "2.3.2.26", "activity": "S-ubiquitinyl-[E2 ubiquitin-conjugating enzyme]-L-cysteine + [acceptor protein]-L-lysine = [E2 ubiquitin-conjugating enzyme]-L-cysteine + N(6)-ubiquitinyl-[acceptor protein]-L-lysine.", "evidence": [ { "id": "F1N6G5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1N6G5" } ] }, { "ec_number": "2.3.2.26", "activity": "", "evidence": [ { "id": "F1N6G5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1N6G5" } ] } ] }, { "uniprot_ac": "F1N703", "gene_name": "UBE3C", "activity": [ { "ec_number": "2.3.2.26", "activity": "S-ubiquitinyl-[E2 ubiquitin-conjugating enzyme]-L-cysteine + [acceptor protein]-L-lysine = [E2 ubiquitin-conjugating enzyme]-L-cysteine + N(6)-ubiquitinyl-[acceptor protein]-L-lysine.", "evidence": [ { "id": "F1N703", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1N703" } ] }, { "ec_number": "2.3.2.26", "activity": "", "evidence": [ { "id": "F1N703", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1N703" } ] } ] }, { "uniprot_ac": "F1N7A0", "gene_name": "HECTD2", "activity": [ { "ec_number": "2.3.2.26", "activity": "S-ubiquitinyl-[E2 ubiquitin-conjugating enzyme]-L-cysteine + [acceptor protein]-L-lysine = [E2 ubiquitin-conjugating enzyme]-L-cysteine + N(6)-ubiquitinyl-[acceptor protein]-L-lysine.", "evidence": [ { "id": "F1N7A0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1N7A0" } ] }, { "ec_number": "2.3.2.26", "activity": "", "evidence": [ { "id": "F1N7A0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1N7A0" } ] } ] }, { "uniprot_ac": "P61085", "gene_name": "UBE2K", "activity": [ { "ec_number": "2.3.2.23", "activity": "S-ubiquitinyl-[E1 ubiquitin-activating enzyme]-L-cysteine + [E2 ubiquitin-conjugating enzyme]-L-cysteine = [E1 ubiquitin-activating enzyme]-L-cysteine + S-ubiquitinyl-[E2 ubiquitin-conjugating enzyme]-L-cysteine.", "evidence": [ { "id": "P61085", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P61085" } ] }, { "ec_number": "2.3.2.23", "activity": "", "evidence": [ { "id": "P61085", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P61085" } ] } ] }, { "uniprot_ac": "Q0II22", "gene_name": "RNF126", "activity": [ { "ec_number": "2.3.2.27", "activity": "S-ubiquitinyl-[E2 ubiquitin-conjugating enzyme]-L-cysteine + [acceptor protein]-L-lysine = [E2 ubiquitin-conjugating enzyme]-L-cysteine + N(6)-ubiquitinyl-[acceptor protein]-L-lysine.", "evidence": [ { "id": "Q0II22", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q0II22" } ] }, { "ec_number": "2.3.2.27", "activity": "", "evidence": [ { "id": "Q0II22", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q0II22" } ] } ] }, { "uniprot_ac": "Q0P5K3", "gene_name": "UBE2N", "activity": [ { "ec_number": "2.3.2.23", "activity": "S-ubiquitinyl-[E1 ubiquitin-activating enzyme]-L-cysteine + [E2 ubiquitin-conjugating enzyme]-L-cysteine = [E1 ubiquitin-activating enzyme]-L-cysteine + S-ubiquitinyl-[E2 ubiquitin-conjugating enzyme]-L-cysteine.", "evidence": [ { "id": "Q0P5K3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q0P5K3" } ] }, { "ec_number": "2.3.2.23", "activity": "", "evidence": [ { "id": "Q0P5K3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q0P5K3" } ] } ] }, { "uniprot_ac": "Q17QG5", "gene_name": "UBE2G2", "activity": [ { "ec_number": "2.3.2.23", "activity": "S-ubiquitinyl-[E1 ubiquitin-activating enzyme]-L-cysteine + [E2 ubiquitin-conjugating enzyme]-L-cysteine = [E1 ubiquitin-activating enzyme]-L-cysteine + S-ubiquitinyl-[E2 ubiquitin-conjugating enzyme]-L-cysteine.", "evidence": [ { "id": "Q17QG5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q17QG5" } ] }, { "ec_number": "2.3.2.23", "activity": "", "evidence": [ { "id": "Q17QG5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q17QG5" } ] } ] }, { "uniprot_ac": "Q1JQA1", "gene_name": "UBE3D", "activity": [ { "ec_number": "2.3.2.26", "activity": "S-ubiquitinyl-[E2 ubiquitin-conjugating enzyme]-L-cysteine + [acceptor protein]-L-lysine = [E2 ubiquitin-conjugating enzyme]-L-cysteine + N(6)-ubiquitinyl-[acceptor protein]-L-lysine.", "evidence": [ { "id": "Q1JQA1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q1JQA1" } ] }, { "ec_number": "2.3.2.26", "activity": "", "evidence": [ { "id": "Q1JQA1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q1JQA1" } ] } ] }, { "uniprot_ac": "Q1RML1", "gene_name": "UBE2S", "activity": [ { "ec_number": "2.3.2.23", "activity": "S-ubiquitinyl-[E1 ubiquitin-activating enzyme]-L-cysteine + [E2 ubiquitin-conjugating enzyme]-L-cysteine = [E1 ubiquitin-activating enzyme]-L-cysteine + S-ubiquitinyl-[E2 ubiquitin-conjugating enzyme]-L-cysteine.", "evidence": [ { "id": "Q1RML1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q1RML1" } ] }, { "ec_number": "2.3.2.23", "activity": "", "evidence": [ { "id": "Q1RML1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q1RML1" } ] } ] }, { "uniprot_ac": "Q1RMW1", "gene_name": "UBE2F", "activity": [ { "ec_number": "2.3.2.34", "activity": "[E1 NEDD8-activating enzyme]-S-[NEDD8 protein]-yl-L-cysteine + [E2 NEDD8-conjugating enzyme]-L-cysteine = [E1 NEDD8-activating enzyme]-L-cysteine + [E2 NEDD8-conjugating enzyme]-S-[NEDD8-protein]-yl-L-cysteine.", "evidence": [ { "id": "Q1RMW1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q1RMW1" } ] }, { "ec_number": "2.3.2.34", "activity": "", "evidence": [ { "id": "Q1RMW1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q1RMW1" } ] } ] }, { "uniprot_ac": "Q1RMX2", "gene_name": "UBE2D2", "activity": [ { "ec_number": "2.3.2.24", "activity": "S-ubiquitinyl-[E1 ubiquitin-activating enzyme]-L-cysteine + [acceptor protein]-L-lysine = [E1 ubiquitin-activating enzyme]-L-cysteine + N(6)-monoubiquitinyl-[acceptor protein]-L-lysine.", "evidence": [ { "id": "Q1RMX2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q1RMX2" } ] }, { "ec_number": "2.3.2.23", "activity": "S-ubiquitinyl-[E1 ubiquitin-activating enzyme]-L-cysteine + [E2 ubiquitin-conjugating enzyme]-L-cysteine = [E1 ubiquitin-activating enzyme]-L-cysteine + S-ubiquitinyl-[E2 ubiquitin-conjugating enzyme]-L-cysteine.", "evidence": [ { "id": "Q1RMX2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q1RMX2" } ] }, { "ec_number": "2.3.2.23", "activity": "", "evidence": [ { "id": "Q1RMX2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q1RMX2" } ] } ] }, { "uniprot_ac": "Q29RQ5", "gene_name": "TRIM9", "activity": [ { "ec_number": "2.3.2.27", "activity": "S-ubiquitinyl-[E2 ubiquitin-conjugating enzyme]-L-cysteine + [acceptor protein]-L-lysine = [E2 ubiquitin-conjugating enzyme]-L-cysteine + N(6)-ubiquitinyl-[acceptor protein]-L-lysine.", "evidence": [ { "id": "Q29RQ5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q29RQ5" } ] }, { "ec_number": "2.3.2.27", "activity": "", "evidence": [ { "id": "Q29RQ5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q29RQ5" } ] } ] }, { "uniprot_ac": "Q2T9X7", "gene_name": "UBE2E3", "activity": [ { "ec_number": "2.3.2.23", "activity": "S-ubiquitinyl-[E1 ubiquitin-activating enzyme]-L-cysteine + [E2 ubiquitin-conjugating enzyme]-L-cysteine = [E1 ubiquitin-activating enzyme]-L-cysteine + S-ubiquitinyl-[E2 ubiquitin-conjugating enzyme]-L-cysteine.", "evidence": [ { "id": "Q2T9X7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q2T9X7" } ] }, { "ec_number": "2.3.2.23", "activity": "", "evidence": [ { "id": "Q2T9X7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q2T9X7" } ] } ] }, { "uniprot_ac": "Q2TA03", "gene_name": "UBE2J2", "activity": [ { "ec_number": "2.3.2.23", "activity": "S-ubiquitinyl-[E1 ubiquitin-activating enzyme]-L-cysteine + [E2 ubiquitin-conjugating enzyme]-L-cysteine = [E1 ubiquitin-activating enzyme]-L-cysteine + S-ubiquitinyl-[E2 ubiquitin-conjugating enzyme]-L-cysteine.", "evidence": [ { "id": "Q2TA03", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q2TA03" } ] }, { "ec_number": "2.3.2.23", "activity": "", "evidence": [ { "id": "Q2TA03", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q2TA03" } ] } ] }, { "uniprot_ac": "Q2TA10", "gene_name": "UBE2D1", "activity": [ { "ec_number": "2.3.2.24", "activity": "S-ubiquitinyl-[E1 ubiquitin-activating enzyme]-L-cysteine + [acceptor protein]-L-lysine = [E1 ubiquitin-activating enzyme]-L-cysteine + N(6)-monoubiquitinyl-[acceptor protein]-L-lysine.", "evidence": [ { "id": "Q2TA10", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q2TA10" } ] }, { "ec_number": "2.3.2.23", "activity": "S-ubiquitinyl-[E1 ubiquitin-activating enzyme]-L-cysteine + [E2 ubiquitin-conjugating enzyme]-L-cysteine = [E1 ubiquitin-activating enzyme]-L-cysteine + S-ubiquitinyl-[E2 ubiquitin-conjugating enzyme]-L-cysteine.", "evidence": [ { "id": "Q2TA10", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q2TA10" } ] }, { "ec_number": "2.3.2.23", "activity": "", "evidence": [ { "id": "Q2TA10", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q2TA10" } ] } ] }, { "uniprot_ac": "Q32L27", "gene_name": "UBE2Q2", "activity": [ { "ec_number": "2.3.2.23", "activity": "S-ubiquitinyl-[E1 ubiquitin-activating enzyme]-L-cysteine + [E2 ubiquitin-conjugating enzyme]-L-cysteine = [E1 ubiquitin-activating enzyme]-L-cysteine + S-ubiquitinyl-[E2 ubiquitin-conjugating enzyme]-L-cysteine.", "evidence": [ { "id": "Q32L27", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q32L27" } ] }, { "ec_number": "2.3.2.23", "activity": "", "evidence": [ { "id": "Q32L27", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q32L27" } ] } ] }, { "uniprot_ac": "Q32LN1", "gene_name": "UBE2H", "activity": [ { "ec_number": "2.3.2.24", "activity": "S-ubiquitinyl-[E1 ubiquitin-activating enzyme]-L-cysteine + [acceptor protein]-L-lysine = [E1 ubiquitin-activating enzyme]-L-cysteine + N(6)-monoubiquitinyl-[acceptor protein]-L-lysine.", "evidence": [ { "id": "Q32LN1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q32LN1" } ] }, { "ec_number": "2.3.2.23", "activity": "S-ubiquitinyl-[E1 ubiquitin-activating enzyme]-L-cysteine + [E2 ubiquitin-conjugating enzyme]-L-cysteine = [E1 ubiquitin-activating enzyme]-L-cysteine + S-ubiquitinyl-[E2 ubiquitin-conjugating enzyme]-L-cysteine.", "evidence": [ { "id": "Q32LN1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q32LN1" } ] }, { "ec_number": "2.3.2.23", "activity": "", "evidence": [ { "id": "Q32LN1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q32LN1" } ] }, { "ec_number": "2.3.2.24", "activity": "", "evidence": [ { "id": "Q32LN1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q32LN1" } ] } ] }, { "uniprot_ac": "Q32LN5", "gene_name": "RNF138", "activity": [ { "ec_number": "2.3.2.27", "activity": "S-ubiquitinyl-[E2 ubiquitin-conjugating enzyme]-L-cysteine + [acceptor protein]-L-lysine = [E2 ubiquitin-conjugating enzyme]-L-cysteine + N(6)-ubiquitinyl-[acceptor protein]-L-lysine.", "evidence": [ { "id": "Q32LN5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q32LN5" } ] }, { "ec_number": "2.3.2.27", "activity": "", "evidence": [ { "id": "Q32LN5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q32LN5" } ] } ] }, { "uniprot_ac": "Q32P99", "gene_name": "UBE2B", "activity": [ { "ec_number": "2.3.2.23", "activity": "S-ubiquitinyl-[E1 ubiquitin-activating enzyme]-L-cysteine + [E2 ubiquitin-conjugating enzyme]-L-cysteine = [E1 ubiquitin-activating enzyme]-L-cysteine + S-ubiquitinyl-[E2 ubiquitin-conjugating enzyme]-L-cysteine.", "evidence": [ { "id": "Q32P99", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q32P99" } ] }, { "ec_number": "2.3.2.23", "activity": "", "evidence": [ { "id": "Q32P99", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q32P99" } ] } ] }, { "uniprot_ac": "Q32PA5", "gene_name": "UBE2C", "activity": [ { "ec_number": "2.3.2.24", "activity": "S-ubiquitinyl-[E1 ubiquitin-activating enzyme]-L-cysteine + [acceptor protein]-L-lysine = [E1 ubiquitin-activating enzyme]-L-cysteine + N(6)-monoubiquitinyl-[acceptor protein]-L-lysine.", "evidence": [ { "id": "Q32PA5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q32PA5" } ] }, { "ec_number": "2.3.2.23", "activity": "S-ubiquitinyl-[E1 ubiquitin-activating enzyme]-L-cysteine + [E2 ubiquitin-conjugating enzyme]-L-cysteine = [E1 ubiquitin-activating enzyme]-L-cysteine + S-ubiquitinyl-[E2 ubiquitin-conjugating enzyme]-L-cysteine.", "evidence": [ { "id": "Q32PA5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q32PA5" } ] }, { "ec_number": "2.3.2.23", "activity": "", "evidence": [ { "id": "Q32PA5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q32PA5" } ] }, { "ec_number": "2.3.2.24", "activity": "", "evidence": [ { "id": "Q32PA5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q32PA5" } ] } ] }, { "uniprot_ac": "Q3MHP1", "gene_name": "UBE2L3", "activity": [ { "ec_number": "2.3.2.23", "activity": "S-ubiquitinyl-[E1 ubiquitin-activating enzyme]-L-cysteine + [E2 ubiquitin-conjugating enzyme]-L-cysteine = [E1 ubiquitin-activating enzyme]-L-cysteine + S-ubiquitinyl-[E2 ubiquitin-conjugating enzyme]-L-cysteine.", "evidence": [ { "id": "Q3MHP1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q3MHP1" } ] }, { "ec_number": "2.3.2.23", "activity": "", "evidence": [ { "id": "Q3MHP1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q3MHP1" } ] } ] }, { "uniprot_ac": "Q4U5R4", "gene_name": "RNF114", "activity": [ { "ec_number": "2.3.2.27", "activity": "S-ubiquitinyl-[E2 ubiquitin-conjugating enzyme]-L-cysteine + [acceptor protein]-L-lysine = [E2 ubiquitin-conjugating enzyme]-L-cysteine + N(6)-ubiquitinyl-[acceptor protein]-L-lysine.", "evidence": [ { "id": "Q4U5R4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q4U5R4" } ] }, { "ec_number": "2.3.2.27", "activity": "", "evidence": [ { "id": "Q4U5R4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q4U5R4" } ] } ] }, { "uniprot_ac": "Q5E9J6", "gene_name": "RNF34", "activity": [ { "ec_number": "2.3.2.27", "activity": "S-ubiquitinyl-[E2 ubiquitin-conjugating enzyme]-L-cysteine + [acceptor protein]-L-lysine = [E2 ubiquitin-conjugating enzyme]-L-cysteine + N(6)-ubiquitinyl-[acceptor protein]-L-lysine.", "evidence": [ { "id": "Q5E9J6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q5E9J6" } ] }, { "ec_number": "2.3.2.27", "activity": "", "evidence": [ { "id": "Q5E9J6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q5E9J6" } ] } ] }, { "uniprot_ac": "Q7YRV4", "gene_name": "TRIM21", "activity": [ { "ec_number": "2.3.2.27", "activity": "S-ubiquitinyl-[E2 ubiquitin-conjugating enzyme]-L-cysteine + [acceptor protein]-L-lysine = [E2 ubiquitin-conjugating enzyme]-L-cysteine + N(6)-ubiquitinyl-[acceptor protein]-L-lysine.", "evidence": [ { "id": "Q7YRV4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q7YRV4" } ] }, { "ec_number": "2.3.2.27", "activity": "", "evidence": [ { "id": "Q7YRV4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q7YRV4" } ] } ] } ], "biomarkers": [], "structures": [ { "pdb_id": "AF-F1N6G5-F1", "pdb_chain": "global", "start_pos": 1, "end_pos": 909, "overlap": "1.0", "method": "AlphaFold", "type": "alphafold", "resolution": -1.0, "url": "https://data.glygen.org/ln2downloads/pdb/current/AF-F1N6G5-F1.pdb", "url_external": "https://alphafold.ebi.ac.uk/entry/F1N6G5" } ], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "F1N6G5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1N6G5" }, { "id": "PRU00104", "database": "PROSITE", "url": "https://prosite.expasy.org/PRU00104" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "HECT", "eco_id": "ECO_0000255", "start_pos": 574, "end_pos": 909, "start_aa": "Asn", "end_aa": "Ala", "glycosite_overlap": [] } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [ { "ec_number": "2.3.2.26", "ec_name": "S-ubiquitinyl-[E2 ubiquitin-conjugating enzyme]-L-cysteine + [acceptor protein]-L-lysine = [E2 ubiquitin-conjugating enzyme]-L-cysteine + N(6)-ubiquitinyl-[acceptor protein]-L-lysine.", "evidence": [ { "id": "2.3.2.26", "database": "BRENDA Enzymes", "url": "https://www.brenda-enzymes.org/enzyme.php?ecno=2.3.2.26" } ] } ], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" }, { "name": "homologset.oma", "label": "OMA Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 194, "end_pos": 196 }, { "start_pos": 27, "end_pos": 29 }, { "start_pos": 349, "end_pos": 351 }, { "start_pos": 418, "end_pos": 420 }, { "start_pos": 630, "end_pos": 632 }, { "start_pos": 857, "end_pos": 859 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ], "tool_support": { "graph_view": "yes" } }, { "uniprot_canonical_ac": "P28801-1", "uniprot_ac": "P28801", "uniprot_id": "GSTP1_BOVIN", "mass": { "chemical_mass": 23613.0, "monoisotopic_mass": 23613.0 }, "refseq": { "ac": "NP_803482", "name": "glutathione S-transferase P", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_803482" }, "gene_names": [ { "name": "GSTP1", "type": "recommended", "evidence": [ { "id": "P28801", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P28801" } ] }, { "name": "GSTP1", "type": "synonym", "evidence": [ { "id": "NP_803482", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_803482" } ] }, { "name": "LOC281806", "type": "synonym", "evidence": [ { "id": "NP_803482", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_803482" } ] } ], "protein_names": [ { "name": "Glutathione S-transferase P", "type": "recommended", "evidence": [ { "id": "P28801", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P28801/entry#names_and_taxonomy" } ] }, { "name": "2.5.1.18", "type": 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Involved in the formation of glutathione conjugates of both prostaglandin A2 (PGA2) and prostaglandin J2 (PGJ2). Participates in the formation of novel hepoxilin regioisomers. Acts as a negative regulator of ferroptosis by mediating glutathione conjugation and detoxification of 4-hydroxynonenal (4-HNE) reactive aldehyde. Negatively regulates CDK5 activity via p25/p35 translocation to prevent neurodegeneration.", "evidence": [ { "database": "UniProtKB", "id": "P28801", "url": "https://www.uniprot.org/uniprotkb/P28801#function" }, { "database": "UniProtKB", "id": "P09211", "url": "https://www.uniprot.org/uniprotkb/P09211#function" } ] }, { "annotation": "Conjugation of reduced glutathione to a wide number of exogenous and endogenous hydrophobic electrophiles.", "evidence": [ { "database": "UniProtKB", "id": "A0A452DHY4", "url": "https://www.uniprot.org/uniprotkb/A0A452DHY4#function" }, { "database": "UniProtKB", "id": "RU368105", "url": "https://www.uniprot.org/uniprotkb/RU368105#function" } ] }, { "annotation": "GSTP1 analysis allowed to determine that some of amino acid substitutions may generate important changes in protein structure and function.", "evidence": [ { "database": "RefSeq", "id": "NP_803482", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_803482" }, { "database": "PubMed", "id": "30315934", "url": "https://glygen.org/publication/PubMed/30315934" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Bos taurus", "taxid": 9913, "evidence": [ { "database": "UniProtKB", "id": "P28801", "url": "https://www.uniprot.org/uniprotkb/P28801" } ], "common_name": "Bovine", "glygen_name": "Bovine", "reference_species": "Bos taurus [9913]" } ], "gene": [ { "name": "GSTP1", "url": "https://www.uniprot.org/uniprotkb/P28801", "locus": { "chromosome": "29", "start_pos": 45412284, "end_pos": 45409548, "strand": "-", "evidence": [ { "database": "Ensembl Gene", "id": "ENSBTAG00000003548", "url": "https://www.ensembl.org/id/ENSBTAG00000003548" } ] } } ], "crossref": [ { "id": "P28801", "url": "https://alphafold.ebi.ac.uk/entry/P28801", "database": "AlphaFoldDB", "categories": [] }, { "id": "ENSBTAG00000003548", "url": "https://bgee.org/?page=gene&gene_id=ENSBTAG00000003548", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "cd03076", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd03076", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "cd03210", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd03210", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "281806", "url": "https://www.ncbi.nlm.nih.gov/gene/281806", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "525938", "url": "https://www.ncbi.nlm.nih.gov/gene/525938", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR003082", "url": "https://www.ebi.ac.uk/interpro/entry/IPR003082", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR004045", "url": "https://www.ebi.ac.uk/interpro/entry/IPR004045", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR004046", "url": "https://www.ebi.ac.uk/interpro/entry/IPR004046", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR010987", "url": "https://www.ebi.ac.uk/interpro/entry/IPR010987", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR036249", "url": "https://www.ebi.ac.uk/interpro/entry/IPR036249", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR036282", "url": "https://www.ebi.ac.uk/interpro/entry/IPR036282", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR040079", "url": "https://www.ebi.ac.uk/interpro/entry/IPR040079", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR050213", "url": "https://www.ebi.ac.uk/interpro/entry/IPR050213", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "bta:281806", "url": "https://www.genome.jp/dbget-bin/www_bget?bta:281806", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "A0A452DHY4", "url": 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"https://www.ebi.ac.uk/interpro/entry/pfam/PF14497", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "NP_803482", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_803482", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "16437", "url": "https://www.rhea-db.org/rhea/16437", "database": "Rhea", "categories": [ "Enzyme and Pathway" ] }, { "id": "50260", "url": "https://www.rhea-db.org/rhea/50260", "database": "Rhea", "categories": [ "Enzyme and Pathway" ] }, { "id": "50800", "url": "https://www.rhea-db.org/rhea/50800", "database": "Rhea", "categories": [ "Enzyme and Pathway" ] }, { "id": "50804", "url": "https://www.rhea-db.org/rhea/50804", "database": "Rhea", "categories": [ "Enzyme and Pathway" ] }, { "id": "50808", "url": "https://www.rhea-db.org/rhea/50808", "database": "Rhea", "categories": [ "Enzyme and Pathway" ] }, { "id": "85343", "url": "https://www.rhea-db.org/rhea/85343", "database": "Rhea", "categories": [ "Enzyme and Pathway" ] }, { "id": "A0A452DHY4", "url": "https://www.uniprot.org/uniprotkb/A0A452DHY4", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A452DHY4-1", "url": "https://www.uniprot.org/uniprotkb/A0A452DHY4-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "P28801", "url": "https://www.uniprot.org/uniprotkb/P28801", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "P28801-1", "url": "https://www.uniprot.org/uniprotkb/P28801-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MPPYTIVYFPVQGRCEAMRMLLADQGQSWKEEVVAMQSWLQGPLKASCLYGQLPKFQDGDLTLYQSNAILRHLGRTLGLYGKDQQEAALVDMVNDGVEDLRCKYVSLIYTNYEAGKEDYVKALPQHLKPFETLLSQNKGGQAFIVGDQISFADYNLLDLLRIHQVLAPSCLDSFPLLSAYVARLNSRPKLKAFLASPEHMNRPINGNGKQ", "length": 210, "header": "sp|P28801-1|GSTP1_BOVIN Isoform 1 of Glutathione S-transferase P OS=Bos taurus OX=9913 GN=GSTP1 PE=1 SV=2 CANONICAL=P28801-1" }, "isoforms": [ { "isoform_ac": "A0A452DHY4-1", "url": "https://www.uniprot.org/uniprotkb/A0A452DHY4/entry", "sequence": { "sequence": "MLLADQDQSWKEEVVTKESWLQGPLKASCLYGQLPKFQDGDLTLYQSNAILRHLGRSFGLYGTDEREAALVDMVNDGLEDLRRHCGHLIHHKREEDKAQYVQELPVHLQPFETLLSQNQGGQAFIVGDQISFADYNLLDLLLNHQVLVPGCLDPFPLLSAYVARLSARPKLKAFLASPEHVNRPIFGSRKI", "length": 191, "header": "tr|A0A452DHY4-1|GSTP1_BOVIN Computationally mapped isoform of Glutathione S-transferase P OS=Bos taurus OX=9913 GN=GSTP1 PE=1 SV=3 CANONICAL=P28801-1" }, "locus": { "chromosome": "29", "start_pos": 45412078, "end_pos": 45410139, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000004615.8", "url": "https://www.ensembl.org/id/ENSBTAT00000004615.8" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000004615.8", "url": "https://www.ensembl.org/id/ENSBTAP00000004615.8" } ] } }, { "isoform_ac": "P28801-1", "url": "https://www.uniprot.org/uniprotkb/P28801/entry#P28801-1", "sequence": { "sequence": "MPPYTIVYFPVQGRCEAMRMLLADQGQSWKEEVVAMQSWLQGPLKASCLYGQLPKFQDGDLTLYQSNAILRHLGRTLGLYGKDQQEAALVDMVNDGVEDLRCKYVSLIYTNYEAGKEDYVKALPQHLKPFETLLSQNKGGQAFIVGDQISFADYNLLDLLRIHQVLAPSCLDSFPLLSAYVARLNSRPKLKAFLASPEHMNRPINGNGKQ", "length": 210, "header": "sp|P28801-1|GSTP1_BOVIN Isoform 1 of Glutathione S-transferase P OS=Bos taurus OX=9913 GN=GSTP1 PE=1 SV=2 CANONICAL=P28801-1" }, "locus": {} } ], "glycosylation": [], "phosphorylation": [ { "start_pos": 4, "end_pos": 4, "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "residue": "Tyr", "comment": "Phosphotyrosine; by EGFR", "evidence": [ { "database": "UniProtKB", "id": "P28801", "url": "https://www.uniprot.org/uniprotkb/P28801" } ], "site_lbl": "Tyr4" }, { "start_pos": 62, "end_pos": 62, "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "residue": "Thr", "comment": "Phosphothreonine", "evidence": [ { "database": "UniProtKB", "id": "P28801", "url": "https://www.uniprot.org/uniprotkb/P28801" } ], "site_lbl": "Thr62" } ], "glycation": [], "keywords": [ "enzyme" ], "publication": [ { "title": "Isolation of a cDNA encoding a glutathione S-transferase (GST) class-pi from the bovine ocular ciliary epithelium.", "journal": "Exp. Eye Res.", "date": "1992", "authors": "Hernando N, Mart\u00edn-Alonso J M, Ghosh S, Coca-Prados M", "evidence": [ { "database": "UniProtKB", "id": "P28801", "url": "https://www.uniprot.org/uniprotkb/P28801" } ], "reference": [ { "type": "PubMed", "id": "1478280", "url": "https://glygen.org/publication/PubMed/1478280" } ] }, { "title": "Bovine erythrocyte glutathione S-transferase: purification, inhibition, and complex formation.", "journal": "Biochem. Int.", "date": "1992", "authors": "Xu F, Hultquist D E", "evidence": [ { "database": "UniProtKB", "id": "P28801", "url": "https://www.uniprot.org/uniprotkb/P28801" } ], "reference": [ { "type": "PubMed", "id": "1503563", "url": "https://glygen.org/publication/PubMed/1503563" } ] }, { "title": "Computational prediction of nsSNPs effects on protein function and structure, a prioritization approach for further in vitro studies applied to bovine GSTP1.", "journal": "Free radical biology & medicine", "date": "2018-12", "authors": "Falomir-Lockhart A H, Villegas-Castagnaso E E, Giovambattista G, Rogberg-Mu\u00f1oz A", "evidence": [ { "database": "RefSeq", "id": "NP_803482", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_803482" } ], "reference": [ { "type": "PubMed", "id": "30315934", "url": "https://glygen.org/publication/PubMed/30315934" } ] }, { "title": "Glutathione transferase from bovine placenta. Preparation, biochemical characterization, crystallization, and preliminary crystallographic analysis of a neutral class PI enzyme.", "journal": "J. Biol. Chem.", "date": "1988", "authors": "Sch\u00e4ffer J, Gallay O, Ladenstein R", "evidence": [ { "database": "UniProtKB", "id": "P28801", "url": "https://www.uniprot.org/uniprotkb/P28801" } ], "reference": [ { "type": "PubMed", "id": "3182852", "url": "https://glygen.org/publication/PubMed/3182852" } ] } ], "pathway": [ { "id": "bta:281806", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?bta:281806", "resource": "KEGG Pathway" } ], "orthologs": [], "go_annotation": { "categories": [ { "name": "Molecular Function", "total": 1, "go_terms": [ { "name": "glutathione transferase activity", "id": "GO:0004364", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0004364", "evidence": [ { "database": "UniProtKB", "id": "P28801", "url": "https://www.uniprot.org/uniprotkb/P28801" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 3, "go_terms": [ { "name": "nucleus", "id": "GO:0005634", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005634", "evidence": [ { "database": "UniProtKB", "id": "P28801", "url": "https://www.uniprot.org/uniprotkb/P28801" } ], "pmid": "" }, { "name": "mitochondrion", "id": "GO:0005739", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005739", "evidence": [ { "database": "UniProtKB", "id": "P28801", "url": "https://www.uniprot.org/uniprotkb/P28801" } ], "pmid": "" }, { "name": "cytosol", "id": "GO:0005829", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005829", "evidence": [ { "database": "UniProtKB", "id": "P28801", "url": "https://www.uniprot.org/uniprotkb/P28801" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 5, "go_terms": [ { "name": "prostaglandin metabolic process", "id": "GO:0006693", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006693", "evidence": [ { "database": "UniProtKB", "id": "P28801", "url": "https://www.uniprot.org/uniprotkb/P28801" } ], "pmid": "" }, { "name": "glutathione derivative biosynthetic process", "id": "GO:1901687", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:1901687", "evidence": [ { "database": "UniProtKB", "id": "P28801", "url": "https://www.uniprot.org/uniprotkb/P28801" } ], "pmid": "" }, { "name": "hepoxilin biosynthetic process", "id": "GO:0051122", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0051122", "evidence": [ { "database": "UniProtKB", "id": "P28801", "url": "https://www.uniprot.org/uniprotkb/P28801" } ], "pmid": "" }, { "name": "glutathione metabolic process", "id": "GO:0006749", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006749", "evidence": [ { "database": "UniProtKB", "id": "P28801", "url": "https://www.uniprot.org/uniprotkb/P28801" } ], "pmid": "" }, { "name": "negative regulation of ferroptosis", "id": "GO:0110076", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0110076", "evidence": [ { "database": "UniProtKB", "id": "P28801", "url": "https://www.uniprot.org/uniprotkb/P28801" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [], "ptm_annotation": [], "interactions": [], "reactions": [ { "id": "16437", "name": "", "equation": "RX + glutathione = an S-substituted glutathione + a halide anion + H(+)", "summary": "", "cellular_location": "", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [ "O18879-1", "F1MUX5-1", "F1MX44-1", "A0ABI0P5M0-1", "A0AAA9TW47-1", "F6QEM8-1", "A0ABI0P3R2-1", "A0AAF6Z0W3-1", "P28801-1", "Q2KJG4-1", "A0A3Q1LMV5-1", "F1MVX2-1", "Q28035-1", "Q9N0V4-1", "Q2NL00-1", "F1MXY2-1", "E1BED9-1", "A0ABI0P006-1", "Q5E9G0-1", "Q64L89-1", "A0A452DIU1-1", "F1MGZ9-1", "A0AAA9TXU3-1", "E1BJX2-1" ], "evidence": [ { "id": "16437", "database": "Rhea", "url": "https://www.rhea-db.org/rhea/16437" } ] }, { "id": "50260", "name": "", "equation": "11(S)-hydroxy-14(S),15(S)-epoxy-(5Z,8Z,12E)-eicosatrienoate + glutathione = (11S,15S)-dihydroxy-14(R)-S-glutathionyl-(5Z,8Z,12E)-eicosatrienoate", "summary": "", "cellular_location": "", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [ "P28801-1", "Q9N0V4-1" ], "evidence": [ { "id": "50260", "database": "Rhea", "url": "https://www.rhea-db.org/rhea/50260" } ] }, { "id": "50800", "name": "", "equation": "prostaglandin A2 + glutathione = prostaglandin A2-S-(S)-glutathione", "summary": "", "cellular_location": "", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [ "P28801-1", "Q9N0V4-1" ], "evidence": [ { "id": "50800", "database": "Rhea", "url": "https://www.rhea-db.org/rhea/50800" } ] }, { "id": "50804", "name": "", "equation": "prostaglandin J2 + glutathione = prostaglandin J2-S-(R)-glutathione", "summary": "", "cellular_location": "", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [ "P28801-1", "Q28035-1", "Q9N0V4-1" ], "evidence": [ { "id": "50804", "database": "Rhea", "url": "https://www.rhea-db.org/rhea/50804" } ] }, { "id": "50808", "name": "", "equation": "prostaglandin J2 + glutathione = prostaglandin J2-S-(S)-glutathione", "summary": "", "cellular_location": "", "input_participant_list": [], 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"table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 4 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ], "tool_support": { "graph_view": "yes" } }, { "uniprot_canonical_ac": "F1N152-1", "uniprot_ac": "F1N152", "uniprot_id": "HTRA1_BOVIN", "mass": { "chemical_mass": 51907.0, "monoisotopic_mass": 51907.0 }, "refseq": { "ac": "NP_001269011", "name": "serine protease HTRA1 precursor", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001269011" }, "gene_names": [ { "name": "HTRA1", "type": "recommended", "evidence": [ { "id": "F1N152", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1N152" } ] }, { "name": "HTRA1", "type": "synonym", "evidence": [ { "id": "NP_001269011", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001269011" } ] }, { "name": "HTRA", "type": "synonym", "evidence": [ { "id": "F1N152", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1N152" } ] }, { "name": "PRSS11", "type": "synonym", "evidence": [ { "id": "NP_001269011", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001269011" }, { "id": "F1N152", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1N152" } ] } ], "protein_names": [ { "name": "Serine protease HTRA1", "type": "recommended", "evidence": [ { "id": "F1N152", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1N152/entry#names_and_taxonomy" } ] }, { "name": "3.4.21.-", "type": "synonym", "evidence": [ { "id": "F1N152", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1N152/entry#names_and_taxonomy" } ] }, { "name": "High-temperature requirement A serine peptidase 1", "type": "synonym", "evidence": [ { "id": "F1N152", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1N152/entry#names_and_taxonomy" } ] }, { "name": "IGF binding", "type": "synonym", "evidence": [ { "id": "NP_001269011", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001269011" } ] }, { "name": "Serine protease 11", "type": "synonym", "evidence": [ { "id": "F1N152", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1N152/entry#names_and_taxonomy" } ] }, { "name": "high-temperature requirement A serine peptidase 1", "type": "synonym", "evidence": [ { "id": "NP_001269011", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001269011" } ] }, { "name": "protease, serine, 11", "type": "synonym", "evidence": [ { "id": "NP_001269011", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001269011" } ] }, { "name": "serine protease 11", "type": "synonym", "evidence": [ { "id": "NP_001269011", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001269011" } ] }, { "name": "serine protease HTRA1 precursor", "type": "synonym", "evidence": [ { "id": "NP_001269011", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001269011" } ] }, { "name": "serine protease HTRA1", "type": "synonym", "evidence": [ { "id": "NP_001269011", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001269011" } ] } ], "function": [ { "annotation": "Serine protease with a variety of targets, including extracellular matrix proteins such as fibronectin. HTRA1-generated fibronectin fragments further induce synovial cells to up-regulate MMP1 and MMP3 production. May also degrade proteoglycans, such as aggrecan, decorin and fibromodulin. Through cleavage of proteoglycans, may release soluble FGF-glycosaminoglycan complexes that promote the range and intensity of FGF signals in the extracellular space. Regulates the availability of insulin-like growth factors (IGFs) by cleaving IGF-binding proteins. Inhibits signaling mediated by TGF-beta family members. This activity requires the integrity of the catalytic site, although it is unclear whether TGF-beta proteins are themselves degraded. By acting on TGF-beta signaling, may regulate many physiological processes, including retinal angiogenesis and neuronal survival and maturation during development. Intracellularly, degrades TSC2, leading to the activation of TSC2 downstream targets (By similarity).", "evidence": [ { "database": "UniProtKB", "id": "F1N152", "url": "https://www.uniprot.org/uniprotkb/F1N152#function" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Bos taurus", "taxid": 9913, "evidence": [ { "database": "UniProtKB", "id": "F1N152", "url": "https://www.uniprot.org/uniprotkb/F1N152" } ], "common_name": "Bovine", "glygen_name": "Bovine", "reference_species": "Bos taurus [9913]" } ], "gene": [ { "name": "HTRA1", "url": "https://www.uniprot.org/uniprotkb/F1N152", "locus": { "chromosome": "26", "start_pos": 42343167, "end_pos": 42285366, "strand": "-", "evidence": [ { "database": "Ensembl Gene", "id": "ENSBTAG00000008389", "url": "https://www.ensembl.org/id/ENSBTAG00000008389" } ] } } ], "crossref": [ { "id": "F1N152", "url": "https://alphafold.ebi.ac.uk/entry/F1N152", "database": "AlphaFoldDB", "categories": [] }, { "id": "ENSBTAG00000008389", "url": "https://bgee.org/?page=gene&gene_id=ENSBTAG00000008389", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "cd00104", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd00104", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "cd06785", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd06785", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "282326", "url": "https://www.ncbi.nlm.nih.gov/gene/282326", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR000867", "url": "https://www.ebi.ac.uk/interpro/entry/IPR000867", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR001478", "url": "https://www.ebi.ac.uk/interpro/entry/IPR001478", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR001940", "url": "https://www.ebi.ac.uk/interpro/entry/IPR001940", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR002350", "url": "https://www.ebi.ac.uk/interpro/entry/IPR002350", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR009003", "url": "https://www.ebi.ac.uk/interpro/entry/IPR009003", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR009030", "url": "https://www.ebi.ac.uk/interpro/entry/IPR009030", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR036034", "url": "https://www.ebi.ac.uk/interpro/entry/IPR036034", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR036058", "url": "https://www.ebi.ac.uk/interpro/entry/IPR036058", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR041489", "url": "https://www.ebi.ac.uk/interpro/entry/IPR041489", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "bta:282326", "url": "https://www.genome.jp/dbget-bin/www_bget?bta:282326", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "F1N152", "url": "https://www.orthodb.org/?gene=F1N152", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR22939", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR22939", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR22939:SF13", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR22939:SF13", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00219", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00219", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF07648", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF07648", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF13365", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF13365", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF17820", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF17820", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "R-BTA-1474228", "url": "https://www.reactome.org/PathwayBrowser/#R-BTA-1474228", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "NP_001269011", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001269011", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A452DI93", "url": "https://www.uniprot.org/uniprotkb/A0A452DI93", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A452DI93-1", "url": "https://www.uniprot.org/uniprotkb/A0A452DI93-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "F1N152", "url": "https://www.uniprot.org/uniprotkb/F1N152", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "F1N152-1", "url": "https://www.uniprot.org/uniprotkb/F1N152-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MQPPRAPFLPPPTPPLLLLLLLLAAPASAQPARAGRSAPGAAGCPERCDPARCAPPPGSCEGGRVRDACGCCEVCGAPEGAECGLQEGPCGEGLQCVVPFGVPASATVRRRAQSGLCVCASNEPVCGSDAKTYTNLCQLRAASRRSERLHQPPVIVLQRGACGQGQEDPNSLRHKYNFIADVVEKIAPAVVHIELFRKLPFSKREVPVASGSGFIVSEDGLIVTNAHVVTNKHRVKVELKNGATYEAKIKDVDEKADIALIKIDHQGKLPVLLLGRSSELRPGEFVVAIGSPFSLQNTVTTGIVSTTQRGGKELGLRNSDMDYIQTDAIINYGNSGGPLVNLDGEVIGINTLKVTAGISFAIPSDKIKKFLTESHDRQAKGKAITKKKYIGIRMMSLTPSKAKELKDRHRDFPDVLSGAYIIEVIPDTPAEAGGLKENDVIISINGQSVVSANDVSDVIKKESTLNMVVRRGNEDIMITVIPEEIDP", "length": 487, "header": "sp|F1N152-1|HTRA1_BOVIN Isoform 1 of Serine protease HTRA1 OS=Bos taurus OX=9913 GN=HTRA1 PE=2 SV=1 CANONICAL=F1N152-1" }, "isoforms": [ { "isoform_ac": "A0A452DI93-1", "url": "https://www.uniprot.org/uniprotkb/A0A452DI93/entry", "sequence": { "sequence": "MGWAARPRALARPESLPRSARSRSPALAQPAAAAAAAVGVAMQPPRAPFLPPPTPPLLLLLLLLAAPASAQPARAGRSAPGAAGCPERCDPARCAPPPGSCEGGRVRDACGCCEVCGAPEGAECGLQEGPCGEGLQCVVPFGVPASATVRRRAQSGLCVCASNEPVCGSDAKTYTNLCQLRAASRRSERLHQPPVIVLQRGACGQGQEDPNSLRHKYNFIADVVEKIAPAVVHIELFRKLPFSKREVPVASGSGFIVSEDGLIVTNAHVVTNKHRVKVELKNGATYEAKIKDVDEKADIALIKIDHQGKLPVLLLGRSSELRPGEFVVAIGSPFSLQNTVTTGIVSTTQRGGKELGLRNSDMDYIQTDAIINYGNSGGPLVNLDGEVIGINTLKVTAGISFAIPSDKIKKFLTESHDRQAKGKAITKKKYIGIRMMSLTPSSKAKELKDRHRDFPDVLSGAYIIEVIPDTPAEAGGLKENDVIISINGQSVVSANDVSDVIKKESTLNMVVRRGNEDIMITVIPEEIDP", "length": 529, "header": "tr|A0A452DI93-1|HTRA1_BOVIN Computationally mapped isoform of Serine protease HTRA1 OS=Bos taurus OX=9913 GN=HTRA1 PE=2 SV=2 CANONICAL=F1N152-1" }, "locus": { "chromosome": "26", "start_pos": 42342618, "end_pos": 42285565, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000011042.6", "url": "https://www.ensembl.org/id/ENSBTAT00000011042.6" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000011042.6", "url": "https://www.ensembl.org/id/ENSBTAP00000011042.6" } ] } }, { "isoform_ac": "F1N152-1", "url": "https://www.uniprot.org/uniprotkb/F1N152/entry#F1N152-1", "sequence": { "sequence": "MQPPRAPFLPPPTPPLLLLLLLLAAPASAQPARAGRSAPGAAGCPERCDPARCAPPPGSCEGGRVRDACGCCEVCGAPEGAECGLQEGPCGEGLQCVVPFGVPASATVRRRAQSGLCVCASNEPVCGSDAKTYTNLCQLRAASRRSERLHQPPVIVLQRGACGQGQEDPNSLRHKYNFIADVVEKIAPAVVHIELFRKLPFSKREVPVASGSGFIVSEDGLIVTNAHVVTNKHRVKVELKNGATYEAKIKDVDEKADIALIKIDHQGKLPVLLLGRSSELRPGEFVVAIGSPFSLQNTVTTGIVSTTQRGGKELGLRNSDMDYIQTDAIINYGNSGGPLVNLDGEVIGINTLKVTAGISFAIPSDKIKKFLTESHDRQAKGKAITKKKYIGIRMMSLTPSKAKELKDRHRDFPDVLSGAYIIEVIPDTPAEAGGLKENDVIISINGQSVVSANDVSDVIKKESTLNMVVRRGNEDIMITVIPEEIDP", "length": 487, "header": "sp|F1N152-1|HTRA1_BOVIN Isoform 1 of Serine protease HTRA1 OS=Bos taurus OX=9913 GN=HTRA1 PE=2 SV=1 CANONICAL=F1N152-1" }, "locus": {} } ], "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "other", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 13, "start_aa": "Thr", "end_pos": 13, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr13", "evidence": [ { "id": "", "database": "GlyGen", "url": "https://data.glygen.org/" } ], "filter_code": "000000000000000010000.00000000001000.0.01000" } ], "phosphorylation": [], "glycation": [], "keywords": [ "enzyme", "glycoprotein", "glycoprotein_predicted" ], "publication": [ { "title": "A whole-genome assembly of the domestic cow, Bos taurus.", "journal": "Genome Biol.", "date": "2009", "authors": "Zimin Aleksey V, Delcher Arthur L, Florea Liliana, Kelley David R, Schatz Michael C, Puiu Daniela, Hanrahan Finnian, Pertea Geo, Van Tassell Curtis P, Sonstegard Tad S, Mar\u00e7ais Guillaume, Roberts Michael, Subramanian Poorani, Yorke James A, Salzberg Steven L", "evidence": [ { "database": "UniProtKB", "id": "F1N152", "url": "https://www.uniprot.org/uniprotkb/F1N152" } ], "reference": [ { "type": "PubMed", "id": "19393038", "url": "https://glygen.org/publication/PubMed/19393038" } ] }, { "title": "Human HtrA, an evolutionarily conserved serine protease identified as a differentially expressed gene product in osteoarthritic cartilage.", "journal": "J. Biol. Chem.", "date": "1998", "authors": "Hu SI, Carozza M, Klein M, Nantermet P, Luk D, Crowl RM", "evidence": [ { "database": "UniProtKB", "id": "F1N152", "url": "https://www.uniprot.org/uniprotkb/F1N152" } ], "reference": [ { "type": "PubMed", "id": "9852107", "url": "https://glygen.org/publication/PubMed/9852107" } ] } ], "pathway": [ { "id": "bta:282326", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?bta:282326", "resource": "KEGG Pathway" }, { "id": "R-BTA-1474228", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-BTA-1474228", "resource": "Reactome", "description": "Degradation of the extracellular matrix" } ], "orthologs": [], "go_annotation": { "categories": [ { "name": "Molecular Function", "total": 3, "go_terms": [ { "name": "serine-type endopeptidase activity", "id": "GO:0004252", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0004252", "evidence": [ { "database": "UniProtKB", "id": "F1N152", "url": "https://www.uniprot.org/uniprotkb/F1N152" } ], "pmid": "" }, { "name": "growth factor binding", "id": "GO:0019838", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0019838", "evidence": [ { "database": "UniProtKB", "id": "F1N152", "url": "https://www.uniprot.org/uniprotkb/F1N152" } ], "pmid": "" }, { "name": "identical protein binding", "id": "GO:0042802", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0042802", "evidence": [ { "database": "UniProtKB", "id": "F1N152", "url": "https://www.uniprot.org/uniprotkb/F1N152" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 4, "go_terms": [ { "name": "extracellular region", "id": "GO:0005576", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005576", "evidence": [ { "database": "UniProtKB", "id": "F1N152", "url": "https://www.uniprot.org/uniprotkb/F1N152" } ], "pmid": "" }, { "name": "cytosol", "id": "GO:0005829", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005829", "evidence": [ { "database": "UniProtKB", "id": "F1N152", "url": "https://www.uniprot.org/uniprotkb/F1N152" } ], "pmid": "" }, { "name": "plasma membrane", "id": "GO:0005886", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005886", "evidence": [ { "database": "UniProtKB", "id": "F1N152", "url": "https://www.uniprot.org/uniprotkb/F1N152" } ], "pmid": "" }, { "name": "extracellular matrix", "id": "GO:0031012", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0031012", "evidence": [ { "database": "UniProtKB", "id": "F1N152", "url": "https://www.uniprot.org/uniprotkb/F1N152" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 3, "go_terms": [ { "name": "proteolysis", "id": "GO:0006508", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006508", "evidence": [ { "database": "UniProtKB", "id": "F1N152", "url": "https://www.uniprot.org/uniprotkb/F1N152" } ], "pmid": "" }, { "name": "positive regulation of apoptotic process", "id": "GO:0043065", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0043065", "evidence": [ { "database": "UniProtKB", "id": "F1N152", "url": "https://www.uniprot.org/uniprotkb/F1N152" } ], "pmid": "" }, { "name": "programmed cell death", "id": "GO:0012501", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0012501", "evidence": [ { "database": "UniProtKB", "id": "F1N152", "url": "https://www.uniprot.org/uniprotkb/F1N152" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [ { "pdb_id": "AF-F1N152-F1", "pdb_chain": "global", "start_pos": 1, "end_pos": 487, "overlap": "1.0", "method": "AlphaFold", "type": "alphafold", "resolution": -1.0, "url": "https://data.glygen.org/ln2downloads/pdb/current/AF-F1N152-F1.pdb", "url_external": "https://alphafold.ebi.ac.uk/entry/F1N152" } ], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "F1N152", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1N152" }, { "id": "PRU00653", "database": "PROSITE", "url": "https://prosite.expasy.org/PRU00653" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "IGFBP N-terminal", "eco_id": "ECO_0000255", "start_pos": 40, "end_pos": 120, "start_aa": "Gly", "end_aa": "Ala", "glycosite_overlap": [] }, { "evidence": [ { "id": "F1N152", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1N152" }, { "id": "PRU00798", "database": "PROSITE", "url": "https://prosite.expasy.org/PRU00798" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "Kazal-like", "eco_id": "ECO_0000255", "start_pos": 105, "end_pos": 164, "start_aa": "Ser", "end_aa": "Gln", "glycosite_overlap": [] }, { "evidence": [ { "id": "F1N152", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1N152" }, { "id": "PRU00143", "database": "PROSITE", "url": "https://prosite.expasy.org/PRU00143" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "PDZ", "eco_id": "ECO_0000255", "start_pos": 372, "end_pos": 474, "start_aa": "Thr", "end_aa": "Glu", "glycosite_overlap": [] } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [ 13 ], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 1 }, { "field": "total_sites", "count": 1 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 1 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "exact_sites", "count": 1 }, { "field": "exact_o_linked_sites", "count": 1 }, { "field": "fuzzy_sites", "count": 0 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", 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"count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 1 }, { "field": "total_sites", "count": 1 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 1 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "exact_sites", "count": 1 }, { "field": "exact_o_linked_sites", "count": 1 }, { "field": "fuzzy_sites", "count": 0 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_pos", "start_aa", "end_pos", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": 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"tool_support": { "graph_view": "yes" } }, { "uniprot_canonical_ac": "P32749-1", "uniprot_ac": "P32749", "uniprot_id": "CHLE_BOVIN", "mass": { "chemical_mass": 68867.0, "monoisotopic_mass": 68867.0 }, "refseq": { "ac": "NP_001070374", "name": "cholinesterase precursor", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001070374" }, "gene_names": [ { "name": "BCHE", "type": "recommended", "evidence": [ { "id": "P32749", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P32749" } ] }, { "name": "BCHE", "type": "synonym", "evidence": [ { "id": "NP_001070374", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001070374" } ] } ], "protein_names": [ { "name": "Cholinesterase", "type": "recommended", "evidence": [ { "id": "P32749", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P32749/entry#names_and_taxonomy" } ] }, { "name": "3.1.1.8", "type": "synonym", "evidence": [ { "id": "P32749", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P32749/entry#names_and_taxonomy" } ] }, { "name": "Acylcholine acylhydrolase", "type": "synonym", "evidence": [ { "id": "P32749", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P32749/entry#names_and_taxonomy" } ] }, { "name": "Butyrylcholine esterase", "type": "synonym", "evidence": [ { "id": "P32749", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P32749/entry#names_and_taxonomy" } ] }, { "name": "Choline esterase II", "type": "synonym", "evidence": [ { "id": "P32749", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P32749/entry#names_and_taxonomy" } ] }, { "name": "Pseudocholinesterase", "type": "synonym", "evidence": [ { "id": "P32749", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P32749/entry#names_and_taxonomy" } ] }, { "name": "acylcholine acylhydrolase", "type": "synonym", "evidence": [ { "id": "NP_001070374", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001070374" } ] }, { "name": "butylcholinesterase", "type": "synonym", "evidence": [ { "id": "NP_001070374", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001070374" } ] }, { "name": "butyrylcholine esterase", "type": "synonym", "evidence": [ { "id": "NP_001070374", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001070374" } ] }, { "name": "choline esterase II", "type": "synonym", "evidence": [ { "id": "NP_001070374", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001070374" } ] }, { "name": "cholinesterase precursor", "type": "synonym", "evidence": [ { "id": "NP_001070374", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001070374" } ] }, { "name": "cholinesterase", "type": "synonym", "evidence": [ { "id": "NP_001070374", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001070374" } ] }, { "name": "pseudocholinesterase", "type": "synonym", "evidence": [ { "id": "NP_001070374", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001070374" } ] } ], "function": [ { "annotation": "Esterase with broad substrate specificity. Contributes to the inactivation of the neurotransmitter acetylcholine. Can degrade neurotoxic organophosphate esters.", "evidence": [ { "database": "UniProtKB", "id": "A0A452DIF3", "url": "https://www.uniprot.org/uniprotkb/A0A452DIF3#function" }, { "database": "UniProtKB", "id": "ARBA00037444", "url": "https://www.uniprot.org/uniprotkb/ARBA00037444#function" }, { "database": "UniProtKB", "id": "P32749", "url": "https://www.uniprot.org/uniprotkb/P32749#function" }, { "database": "UniProtKB", "id": "A0AAF7AFF3", "url": "https://www.uniprot.org/uniprotkb/A0AAF7AFF3#function" } ] }, { "annotation": "The structure of bovine pancreatic RNase A has been determined in complex with 2'-deoxyguanosine-5'-monophosphateat 1.33 A resolution.", "evidence": [ { "database": "RefSeq", "id": "NP_001070374", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001070374" }, { "database": "PubMed", "id": "17768339", "url": "https://glygen.org/publication/PubMed/17768339" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Bos taurus", "taxid": 9913, "evidence": [ { "database": "UniProtKB", "id": "P32749", "url": "https://www.uniprot.org/uniprotkb/P32749" } ], "common_name": "Bovine", "glygen_name": "Bovine", "reference_species": "Bos taurus [9913]" } ], "gene": [ { "name": "BCHE", "url": "https://www.uniprot.org/uniprotkb/P32749", "locus": { "chromosome": "1", "start_pos": 101608729, "end_pos": 101522656, "strand": "-", "evidence": [ { "database": "Ensembl Gene", "id": "ENSBTAG00000011139", "url": "https://www.ensembl.org/id/ENSBTAG00000011139" } ] } } ], "crossref": [ { "id": "P32749", "url": "https://alphafold.ebi.ac.uk/entry/P32749", "database": "AlphaFoldDB", "categories": [] }, { "id": "ENSBTAG00000011139", "url": "https://bgee.org/?page=gene&gene_id=ENSBTAG00000011139", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "3.1.1.8", "url": "https://www.brenda-enzymes.org/enzyme.php?ecno=3.1.1.8&UniProtAcc=P32749", "database": "BRENDA", "categories": [ "Enzyme and Pathway" ] }, { "id": "cd00312", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd00312", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "534616", "url": "https://www.ncbi.nlm.nih.gov/gene/534616", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR000997", "url": "https://www.ebi.ac.uk/interpro/entry/IPR000997", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR002018", "url": "https://www.ebi.ac.uk/interpro/entry/IPR002018", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR014788", "url": "https://www.ebi.ac.uk/interpro/entry/IPR014788", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR019819", "url": "https://www.ebi.ac.uk/interpro/entry/IPR019819", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR019826", "url": "https://www.ebi.ac.uk/interpro/entry/IPR019826", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR029058", "url": "https://www.ebi.ac.uk/interpro/entry/IPR029058", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR050654", "url": "https://www.ebi.ac.uk/interpro/entry/IPR050654", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "bta:534616", "url": "https://www.genome.jp/dbget-bin/www_bget?bta:534616", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "YICPGID", "url": "https://omabrowser.org/oma/group/YICPGID/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "A0A452DIF3", "url": "https://www.orthodb.org/?gene=A0A452DIF3", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "P32749", "url": "https://www.orthodb.org/?gene=P32749", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR43918", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR43918", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR43918:SF5", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR43918:SF5", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00135", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00135", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF08674", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF08674", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "R-BTA-422085", "url": "https://www.reactome.org/PathwayBrowser/#R-BTA-422085", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "R-BTA-9749641", "url": "https://www.reactome.org/PathwayBrowser/#R-BTA-9749641", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "NP_001070374", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001070374", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "21964", "url": "https://www.rhea-db.org/rhea/21964", "database": "Rhea", "categories": [ "Enzyme and Pathway" ] }, { "id": "A0A452DIF3", "url": "https://www.uniprot.org/uniprotkb/A0A452DIF3", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A452DIF3-1", "url": "https://www.uniprot.org/uniprotkb/A0A452DIF3-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0AAF7AFF3", "url": "https://www.uniprot.org/uniprotkb/A0AAF7AFF3", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0AAF7AFF3-1", "url": "https://www.uniprot.org/uniprotkb/A0AAF7AFF3-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "P32749", "url": "https://www.uniprot.org/uniprotkb/P32749", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "P32749-1", "url": "https://www.uniprot.org/uniprotkb/P32749-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MQSRSTVIYIRFVLWFLLLWVLFEKSHTEEDIIITTKNGKVRGMHLPVLGGTVTAFLGIPYAQPPLGRLRFKKPQSLTKWPDIWNATKYANSCYQNTDQSFPGFLGSEMWNPNTDLSEDCLYLNVWIPTPKPKNATVMIWIYGGSFQTGTSSLHVYDGKFLARVERVIVVSMNYRVGALGFLALPGNPEAPGNVGLFDQQLALQWVQKNIAAFGGNPKSVTLFGESAGAASVSLHLLSPESHPLFTRAILQSGSSNAPWAVTSRYEARNRTLTLAKFIGCSRENDTEIIKCLRNKDPQEILRHEVFVVPYGTLLSVNFGPTVDGDFLTDMPDTLLQLGQFKKTQILVGVNKDEGTAFLVYGAPGFSKDNNSIITRKEFQEGLKIFFPGVSEFGKESILFHYMDWLDDQRAEKYREALDDVVGDYNIICPALEFTKKFSDMGNNAFFYYFEHRSSKLPWPEWMGVMHGYEIEFVFGLPLERRVNYTKAEEIFSRSIMKRWANFAKYGNPNGTQNNSTRWPVFKSNEQKYFTLNTESPKVNTKLRAQQCRFWTLFFPKVLEITGNIDEVEREWKAGFHRWNNYMMDWKNQFNDYTSKKESCAGL", "length": 602, "header": "sp|P32749-1|CHLE_BOVIN Isoform 1 of Cholinesterase OS=Bos taurus OX=9913 GN=BCHE PE=2 SV=2 CANONICAL=P32749-1" }, "isoforms": [ { "isoform_ac": "A0A452DIF3-1", "url": "https://www.uniprot.org/uniprotkb/A0A452DIF3/entry", "sequence": { "sequence": "MSVQSNLQAGAAAAYCISLKYYMISTPCKLYHLCCSESETNMQSRSTVIYIRFVLWFLLLWVLFEKSHTEEDIIITTKNGKVRGMHLPVLGGTVTAFLGIPYAQPPLGRLRFKKPQSLTKWPDIWNATKYANSCYQNTDQSFPGFLGSEMWNPNTDLSEDCLYLNVWIPTPKPKNATVMIWIYGGSFQTGTSSLHVYDGKFLARVERVIVVSMNYRVGALGFLALPGNPEAPGNVGLFDQQLALQWVQKNIAAFGGNPKSVTLFGESAGAASVSLHLLSPESHPLFTRAILQSGSSNAPWAVTSRYEARNRTLTLAKFIGCSRENDTEIIKCLRNKDPQEILRHEVFVVPYGTLLSVNFGPTVDGDFLTDMPDTLLQLGQFKKTQILVGVNKDEGTAFLVYGAPGFSKDNNSIITRKEFQEGLKIFFPGVSEFGKESILFHYMDWLDDQRAEKYREALDDVVGDYNIICPALEFTKKFSDMGNNAFFYYFEHRSSKLPWPEWMGVMHGYEIEFVFGLPLERRVNYTKAEEIFSRSIMKRWANFAKYGNPNGTQNNSTRWPVFKSNEQKYFTLNTESPKVNTKLRAQQCRFWTLFFPKVLEITGNIDEVEREWKAGFHRWNNYMMDWKNQFNDYTSKKESCAGL", "length": 643, "header": "tr|A0A452DIF3-1|CHLE_BOVIN Computationally mapped isoform of Cholinesterase OS=Bos taurus OX=9913 GN=BCHE PE=2 SV=1 CANONICAL=P32749-1" }, "locus": { "chromosome": "1", "start_pos": 101600669, "end_pos": 101522749, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000014794.8", "url": "https://www.ensembl.org/id/ENSBTAT00000014794.8" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000014794.6", "url": "https://www.ensembl.org/id/ENSBTAP00000014794.6" } ] } }, { "isoform_ac": "A0AAF7AFF3-1", "url": "https://www.uniprot.org/uniprotkb/A0AAF7AFF3/entry", "sequence": { "sequence": "MSVQSNLQAGAAAAYCISLKYYMISTPCKLYHLCCSESETNMQSRSTVIYIRFVLWFLLLWVLFEKSHTEEDIIITTKNGKVRGMHLPVLGGTVTAFLGIPYAQPPLGRLRFKKPQSLTKWPDIWNATKYANSCYQNTDQSFPGFLGSEMWNPNTDLSEDCLYLNVWIPTPKPKNATVMIWIYGGSFQTGTSSLHVYDGKFLARVERVIVVSMNYRVGALGFLALPGNPEAPGNVGLFDQQLALQWVQKNIAAFGGNPKSVTLFGESAGAASVSLHLLSPESHPLFTRAILQSGSSNAPWAVTSRYEARNRTLTLAKFIGCSRENDTEIIKCLRNKDPQEILRHEVFVVPYGTLLSVNFGPTVDGDFLTDMPDTLLQLGQFKKTQILVGVNKDEGTAFLVYGAPGFSKDNNSIITRKEFQEGLKIFFPGVSEFGKESILFHYMDWLDDQRAEKYREALDDVVGDYNIICPALEFTKKFSDMGNNAFFYYFEHRSSKLPWPEWMGVMHGYEIEFVFGLPLERRVNYTKAEEIFSRSIMKRWANFAKYGNPNGTQNNSTRWPVFKSNEQKYFTLNTESPKVNTKLRAQQCRFWTLFFPKVLEITGNIDEVEREWKAGFHRWNNYMMDWKNQFNDYTSKKESCAVFSLKSCAKY", "length": 651, "header": "tr|A0AAF7AFF3-1|A0AAF7AFF3_BOVIN Computationally mapped isoform of Carboxylic ester hydrolase OS=Bos taurus OX=9913 GN=BCHE PE=3 SV=1 CANONICAL=P32749-1" }, "locus": { "chromosome": "1", "start_pos": 101608613, "end_pos": 101522749, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000068356.3", "url": "https://www.ensembl.org/id/ENSBTAT00000068356.3" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000068076.2", "url": "https://www.ensembl.org/id/ENSBTAP00000068076.2" } ] } }, { "isoform_ac": "P32749-1", "url": "https://www.uniprot.org/uniprotkb/P32749/entry#P32749-1", "sequence": { "sequence": "MQSRSTVIYIRFVLWFLLLWVLFEKSHTEEDIIITTKNGKVRGMHLPVLGGTVTAFLGIPYAQPPLGRLRFKKPQSLTKWPDIWNATKYANSCYQNTDQSFPGFLGSEMWNPNTDLSEDCLYLNVWIPTPKPKNATVMIWIYGGSFQTGTSSLHVYDGKFLARVERVIVVSMNYRVGALGFLALPGNPEAPGNVGLFDQQLALQWVQKNIAAFGGNPKSVTLFGESAGAASVSLHLLSPESHPLFTRAILQSGSSNAPWAVTSRYEARNRTLTLAKFIGCSRENDTEIIKCLRNKDPQEILRHEVFVVPYGTLLSVNFGPTVDGDFLTDMPDTLLQLGQFKKTQILVGVNKDEGTAFLVYGAPGFSKDNNSIITRKEFQEGLKIFFPGVSEFGKESILFHYMDWLDDQRAEKYREALDDVVGDYNIICPALEFTKKFSDMGNNAFFYYFEHRSSKLPWPEWMGVMHGYEIEFVFGLPLERRVNYTKAEEIFSRSIMKRWANFAKYGNPNGTQNNSTRWPVFKSNEQKYFTLNTESPKVNTKLRAQQCRFWTLFFPKVLEITGNIDEVEREWKAGFHRWNNYMMDWKNQFNDYTSKKESCAGL", "length": 602, "header": "sp|P32749-1|CHLE_BOVIN Isoform 1 of Cholinesterase OS=Bos taurus OX=9913 GN=BCHE PE=2 SV=2 CANONICAL=P32749-1" }, "locus": {} } ], "glycosylation": [ { "glytoucan_ac": "", "type": "N-linked", "subtype": "other", "prediction_tool_list": [], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "N", "relation": "attached", "comment": "N-linked (GlcNAc...) asparagine", "icn3d_view": {}, "start_pos": 134, "start_aa": "Asn", "end_pos": 134, "end_aa": "Asn", "residue": "Asn", "site_lbl": "Asn134", "evidence": [ { "id": "P32749", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P32749#ptm_processing" } ], "filter_code": "001000000000000000000.00010000000000.0.01000" }, { "glytoucan_ac": "", "type": "N-linked", "subtype": "other", "prediction_tool_list": [], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "N", "relation": "attached", "comment": "N-linked (GlcNAc...) asparagine", "icn3d_view": {}, "start_pos": 269, "start_aa": "Asn", "end_pos": 269, "end_aa": "Asn", "residue": "Asn", "site_lbl": "Asn269", "evidence": [ { "id": "P32749", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P32749#ptm_processing" } ], "filter_code": "001000000000000000000.00010000000000.0.01000" }, { "glytoucan_ac": "", "type": "N-linked", "subtype": "other", "prediction_tool_list": [], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "N", "relation": "attached", "comment": "N-linked (GlcNAc...) asparagine", "icn3d_view": {}, "start_pos": 284, "start_aa": "Asn", "end_pos": 284, "end_aa": "Asn", "residue": "Asn", "site_lbl": "Asn284", "evidence": [ { "id": "P32749", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P32749#ptm_processing" } ], "filter_code": "001000000000000000000.00010000000000.0.01000" }, { "glytoucan_ac": "", "type": "N-linked", "subtype": "other", "prediction_tool_list": [], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "N", "relation": "attached", "comment": "N-linked (GlcNAc...) asparagine", "icn3d_view": {}, "start_pos": 369, "start_aa": "Asn", "end_pos": 369, "end_aa": "Asn", "residue": "Asn", "site_lbl": "Asn369", "evidence": [ { "id": "P32749", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P32749#ptm_processing" } ], "filter_code": "001000000000000000000.00010000000000.0.01000" }, { "glytoucan_ac": "", "type": "N-linked", "subtype": "other", "prediction_tool_list": [], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "N", "relation": "attached", "comment": "N-linked (GlcNAc...) asparagine", "icn3d_view": {}, "start_pos": 483, "start_aa": "Asn", "end_pos": 483, "end_aa": "Asn", "residue": "Asn", "site_lbl": "Asn483", "evidence": [ { "id": "P32749", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P32749#ptm_processing" } ], "filter_code": "001000000000000000000.00010000000000.0.01000" }, { "glytoucan_ac": "", "type": "N-linked", "subtype": "other", "prediction_tool_list": [], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "N", "relation": "attached", "comment": "N-linked (GlcNAc...) asparagine", "icn3d_view": {}, "start_pos": 509, "start_aa": "Asn", "end_pos": 509, "end_aa": "Asn", "residue": "Asn", "site_lbl": "Asn509", "evidence": [ { "id": "P32749", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P32749#ptm_processing" } ], "filter_code": "001000000000000000000.00010000000000.0.01000" }, { "glytoucan_ac": "", "type": "N-linked", "subtype": "other", "prediction_tool_list": [], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "N", "relation": "attached", "comment": "N-linked (GlcNAc...) asparagine", "icn3d_view": {}, "start_pos": 513, "start_aa": "Asn", "end_pos": 513, "end_aa": "Asn", "residue": "Asn", "site_lbl": "Asn513", "evidence": [ { "id": "P32749", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P32749#ptm_processing" } ], "filter_code": "001000000000000000000.00010000000000.0.01000" }, { "glytoucan_ac": "", "type": "N-linked", "subtype": "other", "prediction_tool_list": [], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "N", "relation": "attached", "comment": "N-linked (GlcNAc...) asparagine", "icn3d_view": {}, "start_pos": 514, "start_aa": "Asn", "end_pos": 514, "end_aa": "Asn", "residue": "Asn", "site_lbl": "Asn514", "evidence": [ { "id": "P32749", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P32749#ptm_processing" } ], "filter_code": "001000000000000000000.00010000000000.0.01000" }, { "glytoucan_ac": "", "type": "N-linked", "subtype": "other", "prediction_tool_list": [], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "N", "relation": "attached", "comment": "N-linked (GlcNAc...) asparagine", "icn3d_view": {}, "start_pos": 85, "start_aa": "Asn", "end_pos": 85, "end_aa": "Asn", "residue": "Asn", "site_lbl": "Asn85", "evidence": [ { "id": "P32749", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P32749#ptm_processing" } ], "filter_code": "001000000000000000000.00010000000000.0.01000" } ], "phosphorylation": [ { "start_pos": 226, "end_pos": 226, "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "residue": "Ser", "comment": "Phosphoserine", "evidence": [ { "database": "UniProtKB", "id": "P32749", "url": "https://www.uniprot.org/uniprotkb/P32749" } ], "site_lbl": "Ser226" } ], "glycation": [], "keywords": [ "enzyme", "glycoprotein", "glycoprotein_predicted" ], "publication": [ { "title": "A new crystal form of bovine pancreatic RNase A in complex with 2'-deoxyguanosine-5'-monophosphate.", "journal": "Acta crystallographica. Section F, Structural biology and crystallization communications", "date": "2007-09-01", "authors": "Larson Steven B, Day John S, Cudney Robert, McPherson Alexander", "evidence": [ { "database": "RefSeq", "id": "NP_001070374", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001070374" } ], "reference": [ { "type": "PubMed", "id": "17768339", "url": "https://glygen.org/publication/PubMed/17768339" } ] }, { "title": "Use of the polymerase chain reaction for homology probing of butyrylcholinesterase from several vertebrates.", "journal": "J. Biol. Chem.", "date": "1991", "authors": "Arpagaus M, Chatonnet A, Masson P, Newton M, Vaughan TA, Bartels CF, Nogueira CP, La Du BN, Lockridge O", "evidence": [ { "database": "UniProtKB", "id": "P32749", "url": "https://www.uniprot.org/uniprotkb/P32749" } ], "reference": [ { "type": "PubMed", "id": "2016308", "url": "https://glygen.org/publication/PubMed/2016308" } ] } ], "pathway": [ { "id": "bta:534616", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?bta:534616", "resource": "KEGG Pathway" }, { "id": "R-BTA-422085", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-BTA-422085", "resource": "Reactome", "description": "Synthesis, secretion, and deacylation of Ghrelin" }, { "id": "R-BTA-9749641", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-BTA-9749641", "resource": "Reactome", "description": "Aspirin ADME" } ], "orthologs": [ { "uniprot_canonical_ac": "A0A061IKL2-1", "protein_name": "Carboxylic ester hydrolase", "gene_name": "Bche", "tax_id": 10029, "organism": "Cricetulus griseus", "sequence": { "sequence": "MTAQRTAVTQTQFCLCFLVVFMLLGKSHTEEDFIVTTKTGRVRGLSLPVLGGTVTSYLGIPYAQPPLGRLRFKKPQPLNKWSGIKNATKYANSCYQNIDQTFPGFPGSEMWNPNTDLSEDCLYLNVWTPAPKPKNATVMVWVYGGGFQTGTSSLPVYDGKFLARVERVIVVSMNYRLGALGFLALPGNSEAPGNMGLFDQQLALQWVQRNIAAFGGNPKSVTLFGESAGAASVSLHLLCPQSYPLFTRAILQSGSSNTPWAVKSPEEARNGTLALAKFTGCSKENDTEMIECLQNKDPQEILVNERFLLPSDSLLSINFGPTVDGDFLTDMPFTLLQLGQVKKTQILVGVNKDEGTGFLVYGAPGFSKDNDSLITRREFQEGLNMYFPRVSSLGKEAILFYYVDWLGDQTPEVYRDALDDVIGDHNIICPALEFTKTFSDLENNAFFYYLEHRSSKVPWPEWMGVMHGYEIEFVFGLPLERRSNYTRAEEMLSRSIMKLWANFAKYGHPNGTQNNSKMWPVFTSTEQKYLTLNTEKSRINSKLRAPQCQFWNLFFPKVEQMTGNIDETEQEWKAGFHRWSNYMMDWKNQFNDYTSKKESCMGL", "length": 603 }, "evidence": [ { "id": "P32749", "url": "https://omabrowser.org/oma/group/P32749/", "database": "OMA" } ], "glygen_name": "Hamster", "common_name": "Chinese hamster" }, { "uniprot_canonical_ac": "A0A8J8XQI9-1", "protein_name": "Carboxylic ester hydrolase", "gene_name": "Bche", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MQTQHTMVTEIHFLLWILLLCMLFGKSHTEEDVIITTKTGRVRGLSMPILGGTVTAFLGIPYAQPPLGSLRFKKPQPLNKWPDVYNATKYANSCYQNIDQAFPGFQGSEMWNPNTNLSEDCLYLNVWIPVPKPKNATVMVWVYGGGFQTGTSSLPVYDGKFLTRVERVIVVSMNYRVGALGFLAFPGNSEAPGNMGLFDQQLALQWIQRNIAAFGGNPKSVTLFGESAGAASVSLHLLCPQSYPLFTRAILESGSSNAPWAVKHPEEARNRTLTLAKFIGCSKENEKEIITCLRSKDPQEILLNEKLVLPSDSIRSINFGPTVDGDFLTDMPHTLLQLGKVKTAQILVGVNKDEGTAFLVYGAPGFSKDNDSLITRREFQEGLNMYFPGVSSLGKEAILFYYVDWLGDQTPEVYREAFDDIIGDYNIICPALEFTKKFAELEINAFFYYFEHRSSKLPWPEWMGVMHGYEIEFVFGLPLERRVNYTRAEEIFSRSIMKTWANFAKYGHPNGTQGNSTVWPVFTSTEQKYLTLNTEKSKINSKLRAPQCQFWRLFFPKVLEITGDIDEREQEWKAGFHRWSNYMMDWKNQFNDYTSKKETCTDL", "length": 603 }, "evidence": [ { "id": "P32749", "url": "https://omabrowser.org/oma/group/P32749/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "P06276-1", "protein_name": "Cholinesterase", "gene_name": "BCHE", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MHSKVTIICIRFLFWFLLLCMLIGKSHTEDDIIIATKNGKVRGMNLTVFGGTVTAFLGIPYAQPPLGRLRFKKPQSLTKWSDIWNATKYANSCCQNIDQSFPGFHGSEMWNPNTDLSEDCLYLNVWIPAPKPKNATVLIWIYGGGFQTGTSSLHVYDGKFLARVERVIVVSMNYRVGALGFLALPGNPEAPGNMGLFDQQLALQWVQKNIAAFGGNPKSVTLFGESAGAASVSLHLLSPGSHSLFTRAILQSGSFNAPWAVTSLYEARNRTLNLAKLTGCSRENETEIIKCLRNKDPQEILLNEAFVVPYGTPLSVNFGPTVDGDFLTDMPDILLELGQFKKTQILVGVNKDEGTAFLVYGAPGFSKDNNSIITRKEFQEGLKIFFPGVSEFGKESILFHYTDWVDDQRPENYREALGDVVGDYNFICPALEFTKKFSEWGNNAFFYYFEHRSSKLPWPEWMGVMHGYEIEFVFGLPLERRDNYTKAEEILSRSIVKRWANFAKYGNPNETQNNSTSWPVFKSTEQKYLTLNTESTRIMTKLRAQQCRFWTSFFPKVLEMTGNIDEAEWEWKAGFHRWNNYMMDWKNQFNDYTSKKESCVGL", "length": 602 }, "evidence": [ { "id": "P32749", "url": "https://omabrowser.org/oma/group/P32749/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "Q03311-1", "protein_name": "Cholinesterase", "gene_name": "Bche", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MQTQHTKVTQTHFLLWILLLCMPFGKSHTEEDFIITTKTGRVRGLSMPVLGGTVTAFLGIPYAQPPLGSLRFKKPQPLNKWPDIHNATQYANSCYQNIDQAFPGFQGSEMWNPNTNLSEDCLYLNVWIPVPKPKNATVMVWIYGGGFQTGTSSLPVYDGKFLARVERVIVVSMNYRVGALGFLAFPGNPDAPGNMGLFDQQLALQWVQRNIAAFGGNPKSITIFGESAGAASVSLHLLCPQSYPLFTRAILESGSSNAPWAVKHPEEARNRTLTLAKFTGCSKENEMEMIKCLRSKDPQEILRNERFVLPSDSILSINFGPTVDGDFLTDMPHTLLQLGKVKKAQILVGVNKDEGTAFLVYGAPGFSKDNDSLITRKEFQEGLNMYFPGVSRLGKEAVLFYYVDWLGEQSPEVYRDALDDVIGDYNIICPALEFTKKFAELENNAFFYFFEHRSSKLPWPEWMGVMHGYEIEFVFGLPLGRRVNYTRAEEIFSRSIMKTWANFAKYGHPNGTQGNSTMWPVFTSTEQKYLTLNTEKSKIYSKLRAPQCQFWRLFFPKVLEMTGDIDETEQEWKAGFHRWSNYMMDWQNQFNDYTSKKESCTAL", "length": 603 }, "evidence": [ { "id": "P32749", "url": "https://omabrowser.org/oma/group/P32749/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" } ], "go_annotation": { "categories": [ { "name": "Biological Process", "total": 2, "go_terms": [ { "name": "choline metabolic process", "id": "GO:0019695", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0019695", "evidence": [ { "database": "UniProtKB", "id": "P32749", "url": "https://www.uniprot.org/uniprotkb/P32749" } ], "pmid": "" }, { "name": "acetylcholine catabolic process", "id": "GO:0006581", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006581", "evidence": [ { "database": "UniProtKB", "id": "P32749", "url": "https://www.uniprot.org/uniprotkb/P32749" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 5, "go_terms": [ { "name": "extracellular space", "id": "GO:0005615", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005615", "evidence": [ { "database": "UniProtKB", "id": "P32749", "url": "https://www.uniprot.org/uniprotkb/P32749" } ], "pmid": "" }, { "name": "plasma membrane", "id": "GO:0005886", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005886", "evidence": [ { "database": "UniProtKB", "id": "P32749", "url": "https://www.uniprot.org/uniprotkb/P32749" } ], "pmid": "" }, { "name": "extracellular region", "id": "GO:0005576", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005576", "evidence": [ { "database": "UniProtKB", "id": "P32749", "url": "https://www.uniprot.org/uniprotkb/P32749" } ], "pmid": "" }, { "name": "nuclear envelope lumen", "id": "GO:0005641", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005641", "evidence": [ { "database": "UniProtKB", "id": "P32749", "url": "https://www.uniprot.org/uniprotkb/P32749" } ], "pmid": "" }, { "name": "endoplasmic reticulum", "id": "GO:0005783", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005783", "evidence": [ { "database": "UniProtKB", "id": "P32749", "url": "https://www.uniprot.org/uniprotkb/P32749" } ], "pmid": "" } ] }, { "name": "Molecular Function", "total": 3, "go_terms": [ { "name": "acetylcholinesterase activity", "id": "GO:0003990", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003990", "evidence": [ { "database": "UniProtKB", "id": "P32749", "url": "https://www.uniprot.org/uniprotkb/P32749" } ], "pmid": "" }, { "name": "cholinesterase activity", "id": "GO:0004104", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0004104", "evidence": [ { "database": "UniProtKB", "id": "P32749", "url": "https://www.uniprot.org/uniprotkb/P32749" } ], "pmid": "" }, { "name": "identical protein binding", "id": "GO:0042802", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0042802", "evidence": [ { "database": "UniProtKB", "id": "P32749", "url": "https://www.uniprot.org/uniprotkb/P32749" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 134, "end_pos": 136, "annotation": "n_glycosylation_sequon" }, { "start_pos": 269, "end_pos": 271, "annotation": "n_glycosylation_sequon" }, { "start_pos": 284, "end_pos": 286, "annotation": "n_glycosylation_sequon" }, { "start_pos": 369, "end_pos": 371, "annotation": "n_glycosylation_sequon" }, { "start_pos": 483, "end_pos": 485, "annotation": "n_glycosylation_sequon" }, { "start_pos": 509, "end_pos": 511, "annotation": "n_glycosylation_sequon" }, { "start_pos": 513, "end_pos": 515, "annotation": "n_glycosylation_sequon" }, { "start_pos": 514, "end_pos": 516, "annotation": "n_glycosylation_sequon" }, { "start_pos": 85, "end_pos": 87, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [ { "id": "21964", "name": "", "equation": "an acylcholine + H2O = a carboxylate + choline + H(+)", "summary": "", "cellular_location": "", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [ "P32749-1" ], "evidence": [ { "id": "21964", "database": "Rhea", "url": "https://www.rhea-db.org/rhea/21964" } ] }, { "id": "R-BTA-9023617", "name": "Butyrylcholinesterase hydrolyzes acyl Ghrelin", "equation": "", "summary": "This event has been computationally inferred from an event that has been demonstrated in another species.

The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.

More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "cellular_location": "extracellular region", "input_participant_list": [ "R-BTA-422069" ], "output_participant_list": [ "R-BTA-422099" ], "enzyme_list": [ "P32749-1" ], "evidence": [ { "id": "R-BTA-9023617", "database": "Reactome", "url": "https://www.reactome.org/PathwayBrowser/#R-BTA-9023617" } ] }, { "id": "R-BTA-9749609", "name": "BCHE hydrolyzes ASA-", "equation": "", "summary": "This event has been computationally inferred from an event that has been demonstrated in another species.

The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.

More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "cellular_location": "extracellular region", "input_participant_list": [ "R-ALL-9749598" ], "output_participant_list": [ "R-ALL-1524044", "R-ALL-9749546" ], "enzyme_list": [ "P32749-1" ], "evidence": [ { "id": "R-BTA-9749609", "database": "Reactome", "url": "https://www.reactome.org/PathwayBrowser/#R-BTA-9749609" } ] } ], "reaction_participants": [ { "participant_id": "R-ALL-1524044", "participant_name": "acetate [extracellular region]", "crossref": [ { "id": "30089", "database": "ChEBI", "url": "" } ] }, { "participant_id": "R-ALL-9749546", "participant_name": "ST [extracellular region]", "crossref": [ { "id": "ZINC000000001554", "database": "ZINC", "url": "" }, { "id": "30762", "database": "ChEBI", "url": "" } ] }, { "participant_id": "R-ALL-9749598", "participant_name": "ASA- [extracellular region]", "crossref": [ { "id": "13719", "database": "ChEBI", "url": "" }, { "id": "ZINC000000000053", "database": "ZINC", "url": "" } ] }, { "participant_id": "R-BTA-422069", "participant_name": "GHRL [extracellular region]", "crossref": [ { "id": "Q9BDJ6", "database": "UniProt", "url": "" }, { "id": "ENSBTAG00000012328", "database": "ENSEMBL", "url": "" }, { "id": "ENSBTAP00000016350", "database": "ENSEMBL", "url": "" }, { "id": "ENSBTAT00000016350", "database": "ENSEMBL", "url": "" }, { "id": "NP_776492.1", "database": "RefSeq", "url": "" }, { "id": "29351", "database": "VGNC", "url": "" } ] }, { "participant_id": "R-BTA-422099", "participant_name": "GHRL [extracellular region]", "crossref": [ { "id": "ENSBTAG00000012328", "database": "ENSEMBL", "url": "" }, { "id": "ENSBTAT00000016350", "database": "ENSEMBL", "url": "" }, { "id": "29351", "database": "VGNC", "url": "" }, { "id": "ENSBTAP00000016350", "database": "ENSEMBL", "url": "" }, { "id": "Q9BDJ6", "database": "UniProt", "url": "" }, { "id": "NP_776492.1", "database": "RefSeq", "url": "" } ] } ], "reaction_enzymes": [ { "uniprot_ac": "P32749", 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"plasminogen activator inhibitor 1 precursor", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_776562" }, "gene_names": [ { "name": "SERPINE1", "type": "recommended", "evidence": [ { "id": "P13909", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P13909" } ] }, { "name": "PAI1", "type": "synonym", "evidence": [ { "id": "NP_776562", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_776562" }, { "id": "P13909", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P13909" } ] }, { "name": "SERPINE1", "type": "synonym", "evidence": [ { "id": "NP_776562", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_776562" } ] } ], "protein_names": [ { "name": "Plasminogen activator inhibitor 1", "type": "recommended", "evidence": [ { "id": "P13909", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P13909/entry#names_and_taxonomy" } ] }, { "name": "Endothelial plasminogen activator inhibitor", 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"database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_776562" } ] }, { "name": "endothelial plasminogen activator inhibitor", "type": "synonym", "evidence": [ { "id": "NP_776562", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_776562" } ] }, { "name": "plasminogen activator inhibitor 1 precursor", "type": "synonym", "evidence": [ { "id": "NP_776562", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_776562" } ] }, { "name": "plasminogen activator inhibitor 1", "type": "synonym", "evidence": [ { "id": "NP_776562", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_776562" } ] }, { "name": "plasminogen activator inhibitor, type 1", "type": "synonym", "evidence": [ { "id": "NP_776562", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_776562" } ] }, { "name": "serine (or cysteine) proteinase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 1", "type": "synonym", "evidence": [ { "id": "NP_776562", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_776562" } ] }, { "name": "serpin E1", "type": "synonym", "evidence": [ { "id": "NP_776562", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_776562" } ] } ], "function": [ { "annotation": "Data show that urokinase-type plasminogen activator (uPA) is only expressed in the cumulus cells of immature and in vitro matured cumulus-oocyte complexes (COCs), while uPA receptor (uPAR) and plasminogen activator inhibitor-1 (PAI-1) are expressed in both the cumulus cells and the immature and in vitro matured oocytes.", "evidence": [ { "database": "RefSeq", "id": "NP_776562", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_776562" }, { "database": "PubMed", "id": "25939353", "url": "https://glygen.org/publication/PubMed/25939353" } ] }, { "annotation": "Data suggest PAI1 plays key role in modulating chromaffin cell neurosecretory function. Evidence is presented that in chromaffin cells, PAI1 is targeted to storage vesicles and co-released with catecholamine upon secretagogue/stress stimulation.", "evidence": [ { "database": "RefSeq", "id": "NP_776562", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_776562" }, { "database": "PubMed", "id": "21596853", "url": "https://glygen.org/publication/PubMed/21596853" } ] }, { "annotation": "FoxO1 inhibits PAI-1 expression through the inhibition of TGF-beta/Smad-mediated signaling pathways.", "evidence": [ { "database": "RefSeq", "id": "NP_776562", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_776562" }, { "database": "PubMed", "id": "19563779", "url": "https://glygen.org/publication/PubMed/19563779" } ] }, { "annotation": "Inhibition of autophagy in theca cells induces CYP17A1 and PAI-1 expression via ROS/p38 and JNK signalling during the development of polycystic ovary syndrome.", "evidence": [ { "database": "RefSeq", "id": "NP_776562", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_776562" }, { "database": "PubMed", "id": "32199904", "url": "https://glygen.org/publication/PubMed/32199904" } ] }, { "annotation": "MicroRNA-10b promotes the apoptosis of bovine ovarian granulosa cells by targeting plasminogen activator inhibitor-1.", "evidence": [ { "database": "RefSeq", "id": "NP_776562", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_776562" }, { "database": "PubMed", "id": "34627051", "url": "https://glygen.org/publication/PubMed/34627051" } ] }, { "annotation": "Serine protease inhibitor. Inhibits TMPRSS7. Is a primary inhibitor of tissue-type plasminogen activator (PLAT) and urokinase-type plasminogen activator (PLAU). As PLAT inhibitor, it is required for fibrinolysis down-regulation and is responsible for the controlled degradation of blood clots. As PLAU inhibitor, it is involved in the regulation of cell adhesion and spreading. Acts as a regulator of cell migration, independently of its role as protease inhibitor. It is required for stimulation of keratinocyte migration during cutaneous injury repair. It is involved in cellular and replicative senescence (By similarity). Plays a role in alveolar type 2 cells senescence in the lung (By similarity). Is involved in the regulation of cementogenic differentiation of periodontal ligament stem cells, and regulates odontoblast differentiation and dentin formation during odontogenesis (By similarity).", "evidence": [ { "database": "UniProtKB", "id": "P13909", "url": "https://www.uniprot.org/uniprotkb/P13909#function" }, { "database": "UniProtKB", "id": "P05121", "url": "https://www.uniprot.org/uniprotkb/P05121#function" }, { "database": "UniProtKB", "id": "P22777", "url": "https://www.uniprot.org/uniprotkb/P22777#function" }, { "database": "UniProtKB", "id": "A0A452DIJ9", "url": "https://www.uniprot.org/uniprotkb/A0A452DIJ9#function" }, { "database": "UniProtKB", "id": "ARBA00057131", "url": "https://www.uniprot.org/uniprotkb/ARBA00057131#function" }, { "database": "UniProtKB", "id": "A0AAA9S0G9", "url": "https://www.uniprot.org/uniprotkb/A0AAA9S0G9#function" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": 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"Protein" ] }, { "id": "A0A452DIJ9-1", "url": "https://www.uniprot.org/uniprotkb/A0A452DIJ9-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0AAA9S0G9", "url": "https://www.uniprot.org/uniprotkb/A0AAA9S0G9", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0AAA9S0G9-1", "url": "https://www.uniprot.org/uniprotkb/A0AAA9S0G9-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "P13909", "url": "https://www.uniprot.org/uniprotkb/P13909", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "P13909-1", "url": "https://www.uniprot.org/uniprotkb/P13909-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MRMSPVFACLALGLALIFGEGSASYQPQSAAASLATDFGVKVFQQVVRASKDRNVVFSPYGVASVLAMLQLTTGGETRQQIQEAMQFKIEEKGMAPAFHRLYKELMGPWNKDEISTADAIFVQRDLELVHGFMPNFFRLFRTTVKQVDFSEVERARFIVNDWVKRHTKGMISDLLGEGAVDQLTRLVLVNALYFNGQWKMPFPESNTHHRLFHKSDGSTISVPMMAQTNKFNYTEFTTPDGRYYDILELPYHGNTLSMLIAAPYEKEVPLSALTSILDAELISQWKGNMTRLTRLLVLPKFSLETEIDLRRPLENLGMTDMFRPSQADFSSFSDQEFLYVSQALQKVKIEVNESGTLASSSTALVVSARMAPEEIIMDRPFLFVVRHNPTGTVLFMGQVMEP", "length": 402, "header": "sp|P13909-1|PAI1_BOVIN Isoform 1 of Plasminogen activator inhibitor 1 OS=Bos taurus OX=9913 GN=SERPINE1 PE=1 SV=1 CANONICAL=P13909-1" }, "isoforms": [ { "isoform_ac": "A0A452DIJ9-1", "url": "https://www.uniprot.org/uniprotkb/A0A452DIJ9/entry", "sequence": { "sequence": "MTSESFRSRDGDRSGHVLGRAQVIPENSRAFVAEATVAHGGRDKIQLNDWRGQAAGCLEGRSRRLWTRCSSNLGLGTPNPDSQLPVPLWPPRVEDKSLGPFWESEMAGGLDFCFLHPRDSRRNCSSSSRLTTFSGTLNQTKKERHKQEAVTDEQSAGNREAAACSGAELLLVEGQRAPSRESHTSFSVEEGLPPSTPAAAAGTNRPSQGTAKFRMRMSPVFACLALGLALIFGEGSASYQPQSAAASLATDFGVKVFQQVVRASKDRNVVFSPYGVASVLAMLQLTTGGETRQQIQEAMQFKIEEKGMAPAFHRLYKELMGPWNKDEISTADAIFVQRDLELVHGFMPNFFRLFRTTVKQVDFSEVERARFIVNDWVKRHTKGMISDLLGEGAVDQLTRLVLVNALYFNGQWKMPFPESNTHHRLFHKSDGSTISVPMMAQTNKFNYTEFTTPDGRYYDILELPYHGNTLSMLIAAPYEKEVPLSALTSILDAELISQWKGNMTRLTRLLVLPKFSLETEIDLRRPLENLGMTDMFRPSQADFSSFSDQEFLYVSQALQKVKIEVNESGTLASSSTALVVSARMAPEEIIMDRPFLFVVRHNPTGTVLFMGQVMEP", "length": 616, "header": "tr|A0A452DIJ9-1|PAI1_BOVIN Computationally mapped isoform of Plasminogen activator inhibitor 1 OS=Bos taurus OX=9913 GN=SERPINE1 PE=1 SV=1 CANONICAL=P13909-1" }, "locus": { "chromosome": "25", "start_pos": 35606297, "end_pos": 35597764, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000019232.5", "url": "https://www.ensembl.org/id/ENSBTAT00000019232.5" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000019232.4", "url": "https://www.ensembl.org/id/ENSBTAP00000019232.4" } ] } }, { "isoform_ac": "A0AAA9S0G9-1", "url": "https://www.uniprot.org/uniprotkb/A0AAA9S0G9/entry", "sequence": { "sequence": "MGTEAVTSLAGPSRRNCSSSSRLTTFSGTLNQTKKERHKQEAVTDEQSAGNREAAACSGAELLLVEGQRAPSRESHTSFSVEEGLPPSTPAAAAGTNRPSQGTAKFRMRMSPVFACLALGLALIFGEGSASYQPQSAAASLATDFGVKVFQQVVRASKDRNVVFSPYGVASVLAMLQLTTGGETRQQIQEAMQFKIEEKGMAPAFHRLYKELMGPWNKDEISTADAIFVQRDLELVHGFMPNFFRLFRTTVKQVDFSEVERARFIVNDWVKRHTKGMISDLLGEGAVDQLTRLVLVNALYFNGQWKMPFPESNTHHRLFHKSDGSTISVPMMAQTNKFNYTEFTTPDGRYYDILELPYHGNTLSMLIAAPYEKEVPLSALTSILDAELISQWKGNMTRLTRLLVLPKFSLETEIDLRRPLENLGMTDMFRPSQADFSSFSDQEFLYVSQALQKVKIEVNESGTLASSSTALVVSARMAPEEIIMDRPFLFVVRHNPTGTVLFMGQVMEP", "length": 509, "header": "tr|A0AAA9S0G9-1|PAI1_BOVIN Computationally mapped isoform of Plasminogen activator inhibitor 1 OS=Bos taurus OX=9913 GN=SERPINE1 PE=1 SV=1 CANONICAL=P13909-1" }, "locus": { "chromosome": "25", "start_pos": 35606269, "end_pos": 35597764, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000098912.1", "url": "https://www.ensembl.org/id/ENSBTAT00000098912.1" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000078466.1", "url": "https://www.ensembl.org/id/ENSBTAP00000078466.1" } ] } }, { "isoform_ac": "P13909-1", "url": "https://www.uniprot.org/uniprotkb/P13909/entry#P13909-1", "sequence": { "sequence": "MRMSPVFACLALGLALIFGEGSASYQPQSAAASLATDFGVKVFQQVVRASKDRNVVFSPYGVASVLAMLQLTTGGETRQQIQEAMQFKIEEKGMAPAFHRLYKELMGPWNKDEISTADAIFVQRDLELVHGFMPNFFRLFRTTVKQVDFSEVERARFIVNDWVKRHTKGMISDLLGEGAVDQLTRLVLVNALYFNGQWKMPFPESNTHHRLFHKSDGSTISVPMMAQTNKFNYTEFTTPDGRYYDILELPYHGNTLSMLIAAPYEKEVPLSALTSILDAELISQWKGNMTRLTRLLVLPKFSLETEIDLRRPLENLGMTDMFRPSQADFSSFSDQEFLYVSQALQKVKIEVNESGTLASSSTALVVSARMAPEEIIMDRPFLFVVRHNPTGTVLFMGQVMEP", "length": 402, "header": "sp|P13909-1|PAI1_BOVIN Isoform 1 of Plasminogen activator inhibitor 1 OS=Bos taurus OX=9913 GN=SERPINE1 PE=1 SV=1 CANONICAL=P13909-1" }, "locus": {} } ], "glycosylation": [ { "glytoucan_ac": "", "type": "N-linked", "subtype": "other", "prediction_tool_list": [], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "N", "relation": "attached", "comment": "N-linked (GlcNAc...) asparagine", "icn3d_view": {}, "start_pos": 232, "start_aa": "Asn", "end_pos": 232, "end_aa": "Asn", "residue": "Asn", "site_lbl": "Asn232", "evidence": [ { "id": "P13909", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P13909#ptm_processing" } ], "filter_code": "001000000000000000000.00010000000000.0.01000" }, { "glytoucan_ac": "", "type": "N-linked", "subtype": "other", "prediction_tool_list": [], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "N", "relation": "attached", "comment": "N-linked (GlcNAc...) asparagine", "icn3d_view": {}, "start_pos": 288, "start_aa": "Asn", "end_pos": 288, "end_aa": "Asn", "residue": "Asn", "site_lbl": "Asn288", "evidence": [ { "id": "P13909", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P13909#ptm_processing" } ], "filter_code": "001000000000000000000.00010000000000.0.01000" }, { "glytoucan_ac": "", "type": "N-linked", "subtype": "other", "prediction_tool_list": [], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "N", "relation": "attached", "comment": "N-linked (GlcNAc...) asparagine", "icn3d_view": {}, "start_pos": 352, "start_aa": "Asn", "end_pos": 352, "end_aa": "Asn", "residue": "Asn", "site_lbl": "Asn352", "evidence": [ { "id": "P13909", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P13909#ptm_processing" } ], "filter_code": "001000000000000000000.00010000000000.0.01000" } ], "phosphorylation": [], "glycation": [], "keywords": [ "glycoprotein", "glycoprotein_predicted" ], "publication": [ { "title": "Characterization of 954 bovine full-CDS cDNA sequences.", "journal": "BMC Genomics", "date": "2005", "authors": "Harhay Gregory P, Sonstegard Tad S, Keele John W, Heaton Michael P, Clawson Michael L, Snelling Warren M, Wiedmann Ralph T, Van Tassell Curt P, Smith Timothy P L", "evidence": [ { "database": "UniProtKB", "id": "P13909", "url": "https://www.uniprot.org/uniprotkb/P13909" } ], "reference": [ { "type": "PubMed", "id": "16305752", "url": "https://glygen.org/publication/PubMed/16305752" } ] }, { "title": "Transforming growth factor-beta 1 modulates basic fibroblast growth factor-induced proteolytic and angiogenic properties of endothelial cells in vitro.", "journal": "J. Cell Biol.", "date": "1990", "authors": "Pepper M S, Belin D, Montesano R, Orci L, Vassalli J D", "evidence": [ { "database": "UniProtKB", "id": "P13909", "url": "https://www.uniprot.org/uniprotkb/P13909" } ], "reference": [ { "type": "PubMed", "id": "1696269", "url": "https://glygen.org/publication/PubMed/1696269" } ] }, { "title": "Forkhead transcription factor FoxO1 inhibits insulin- and transforming growth factor-beta-stimulated plasminogen activator inhibitor-1 expression.", "journal": "Biochemical and biophysical research communications", "date": "2009-09-04", "authors": "Jung Yun-A, Lee Kyeong-Min, Kim Mi-Kyung, Jung Gwon-Soo, Seo Ye-Jin, Kim Hye-Soon, Cho Ho-Chan, Lee Ki-Up, Park Keun-Gyu, Lee In-Kyu", "evidence": [ { "database": "RefSeq", "id": "NP_776562", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_776562" } ], "reference": [ { "type": "PubMed", "id": "19563779", "url": "https://glygen.org/publication/PubMed/19563779" } ] }, { "title": "The anti-fibrinolytic SERPIN, plasminogen activator inhibitor 1 (PAI-1), is targeted to and released from catecholamine storage vesicles.", "journal": "Blood", "date": "2011-06-30", "authors": "Jiang Qijiao, Gingles Neill A, Olivier Marc A, Miles Lindsey A, Parmer Robert J", "evidence": [ { "database": "RefSeq", "id": "NP_776562", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_776562" } ], "reference": [ { "type": "PubMed", "id": "21596853", "url": "https://glygen.org/publication/PubMed/21596853" } ] }, { "title": "cDNA for bovine type 1 plasminogen activator inhibitor (PAI-1).", "journal": "Nucleic Acids Res.", "date": "1989", "authors": "Mimuro J, Sawdey M, Hattori M, Luskutoff D J", "evidence": [ { "database": "UniProtKB", "id": "P13909", "url": "https://www.uniprot.org/uniprotkb/P13909" } ], "reference": [ { "type": "PubMed", "id": "2587231", "url": "https://glygen.org/publication/PubMed/2587231" } ] }, { "title": "Expression and localization of urokinase-type plasminogen activator receptor in bovine cumulus-oocyte complexes.", "journal": "Zygote (Cambridge, England)", "date": "2016-04", "authors": "Garc\u00eda Daniela C, Miceli Dora C, Rizo Gabriela, Garc\u00eda Elina V, Valdecantos Pablo A, Rold\u00e1n-Olarte Mariela", "evidence": [ { "database": "RefSeq", "id": "NP_776562", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_776562" } ], "reference": [ { "type": "PubMed", "id": "25939353", "url": "https://glygen.org/publication/PubMed/25939353" } ] }, { "title": "Inhibition of autophagy in theca cells induces CYP17A1 and PAI-1 expression via ROS/p38 and JNK signalling during the development of polycystic ovary syndrome.", "journal": "Molecular and cellular endocrinology", "date": "2020-05-15", "authors": "Kobayashi Mutsumi, Yoshino Osamu, Nakashima Akitoshi, Ito Masami, Nishio Kazuyuki, Ono Yosuke, Kusabiraki Tae, Kunitomi Chisato, Takahashi Nozomi, Harada Miyuki, Hattori Katsushige, Orisaka Makoto, Osuga Yutaka, Saito Shigeru", "evidence": [ { "database": "RefSeq", "id": "NP_776562", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_776562" } ], "reference": [ { "type": "PubMed", "id": "32199904", "url": "https://glygen.org/publication/PubMed/32199904" } ] }, { "title": "Bovine endothelial cell plasminogen activator inhibitor. Purification and heat activation.", "journal": "Eur. J. Biochem.", "date": "1988", "authors": "Katagiri K, Okada K, Hattori H, Yano M", "evidence": [ { "database": "UniProtKB", "id": "P13909", "url": "https://www.uniprot.org/uniprotkb/P13909" } ], "reference": [ { "type": "PubMed", "id": "3262060", "url": "https://glygen.org/publication/PubMed/3262060" } ] }, { "title": "microRNA-10b promotes the apoptosis of bovine ovarian granulosa cells by targeting plasminogen activator inhibitor-1.", "journal": "Theriogenology", "date": "2021-12", "authors": "Guo Lewei, Huang Qixuan, Zhao Jing, Liu Hongyu, Lu Wenfa, Wang Jun", "evidence": [ { "database": "RefSeq", "id": "NP_776562", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_776562" } ], "reference": [ { "type": "PubMed", "id": "34627051", "url": "https://glygen.org/publication/PubMed/34627051" } ] } ], "pathway": [ { "id": "bta:281375", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?bta:281375", "resource": "KEGG Pathway" }, { "id": "R-BTA-114608", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-BTA-114608", "resource": "Reactome", "description": "Platelet degranulation" }, { "id": "R-BTA-3000178", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-BTA-3000178", "resource": "Reactome", "description": "ECM proteoglycans" }, { "id": "R-BTA-75205", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-BTA-75205", "resource": "Reactome", "description": "Dissolution of Fibrin Clot" }, { "id": "R-BTA-9769739", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-BTA-9769739", "resource": "Reactome", "description": "Regulation of clotting cascade" } ], "orthologs": [ { "uniprot_canonical_ac": "I3LQQ6-1", "protein_name": "Plasminogen activator inhibitor 1", "gene_name": "SERPINE1", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MRMSLVFACLAMGLALIFAEGSASSHHQSLAARLATDFGVKVFRQVVQASKDRNVVFSPYGVASVLAMLQLTTAGDTQQQIQEAMQFKIEEKGMAPALRQLYKELMGPWNKDEISTADAIFVQRDLKLVQGFMPYFFRLFRTTVKQVDFEMDRARFIINDWVKRHTKGMINDLLGQGAVDQLTRLVLVNALYFNGQWKTPFPEKSTHHRLFHKSDGSTVSVPMMAQTNKFNYTEFSTPDGHYYDILELPYHGNTLSMFIAAPYEKEVPLSALTSILDAQLISQWKGNMTRLTRLLVLPKFSLESEVDLRRPLENLGMTDMFRPNQADFSSLSDQELLYMSQALQKVKIEVNESGTVASSSTAIIVSARMAPEEIIMDRPFLFVVRHNPTGTVLFMGQVMEP", "length": 401 }, "evidence": [ { "id": "P13909", "url": "https://omabrowser.org/oma/group/P13909/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "P05121-1", "protein_name": "Plasminogen activator inhibitor 1", "gene_name": "SERPINE1", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MQMSPALTCLVLGLALVFGEGSAVHHPPSYVAHLASDFGVRVFQQVAQASKDRNVVFSPYGVASVLAMLQLTTGGETQQQIQAAMGFKIDDKGMAPALRHLYKELMGPWNKDEISTTDAIFVQRDLKLVQGFMPHFFRLFRSTVKQVDFSEVERARFIINDWVKTHTKGMISNLLGKGAVDQLTRLVLVNALYFNGQWKTPFPDSSTHRRLFHKSDGSTVSVPMMAQTNKFNYTEFTTPDGHYYDILELPYHGDTLSMFIAAPYEKEVPLSALTNILSAQLISHWKGNMTRLPRLLVLPKFSLETEVDLRKPLENLGMTDMFRQFQADFTSLSDQEPLHVAQALQKVKIEVNESGTVASSSTAVIVSARMAPEEIIMDRPFLFVVRHNPTGTVLFMGQVMEP", "length": 402 }, "evidence": [ { "id": "P13909", "url": "https://omabrowser.org/oma/group/P13909/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "P20961-1", "protein_name": "Plasminogen activator inhibitor 1", "gene_name": "Serpine1", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MQMSSALTCLTLGLVLVFGKGFASPLPESHTAQQATNFGVKVFQHVVQASKDRNVVFSPYGVSSVLAMLQLTTAGKTRQQIQDAMGFNISERGTAPALRKLSKELMGSWNKNEISTADAIFVQRDLELVQGFMPHFFKLFRTTVKQVDFSEVERARFIINDWVERHTKGMISDLLAKGAVNELTRLVLVNALYFNGQWKTPFLEASTHQRLFHKSDGSTISVPMMAQNNKFNYTEFTTPDGHEYDILELPYHGETLSMFIAAPFEKDVPLSAITNILDAELIRQWKSNMTRLPRLLILPKFSLETEVDLRGPLEKLGMTDIFSSTQADFTSLSDQEQLSVAQALQKVKIEVNESGTVASSSTAILVSARMAPTEMVLDRSFLFVVRHNPTETILFMGQLMEP", "length": 402 }, "evidence": [ { "id": "P13909", "url": "https://omabrowser.org/oma/group/P13909/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "P22777-1", "protein_name": "Plasminogen activator inhibitor 1", "gene_name": "Serpine1", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MQMSSALACLILGLVLVSGKGFTLPLRESHTAHQATDFGVKVFQQVVQASKDRNVVFSPYGVSSVLAMLQMTTAGKTRRQIQDAMGFKVNEKGTAHALRQLSKELMGPWNKNEISTADAIFVQRDLELVQGFMPHFFKLFQTMVKQVDFSEVERARFIINDWVERHTKGMINDLLAKGAVDELTRLVLVNALYFSGQWKTPFLEASTHQRLFHKSDGSTVSVPMMAQSNKFNYTEFTTPDGLEYDVVELPYQRDTLSMFIAAPFEKDVHLSALTNILDAELIRQWKGNMTRLPRLLILPKFSLETEVDLRGPLEKLGMPDMFSATLADFTSLSDQEQLSVAQALQKVRIEVNESGTVASSSTAFVISARMAPTEMVIDRSFLFVVRHNPTETILFMGQVMEP", "length": 402 }, "evidence": [ { "id": "P13909", "url": "https://omabrowser.org/oma/group/P13909/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q9SH52-1", "protein_name": "Serpin-Z1", "gene_name": "", "tax_id": 3702, "organism": "Arabidopsis thaliana", "sequence": { "sequence": "MDVREAMKNQTHVAMILSGHVLSSAPKDSNVIFSPASINSAITMHAAGPGGDLVSGQILSFLRSSSIDELKTVFRELASVVYADRSATGGPKITAANGLWIDKSLPTDPKFKDLFENFFKAVYVPVDFRSEAEEVRKEVNSWVEHHTNNLIKDLLPDGSVTSLTNKIYANALSFKGAWKRPFEKYYTRDNDFYLVNGTSVSVPFMSSYENQYVRAYDGFKVLRLPYQRGSDDTNRKFSMYFYLPDKKDGLDDLLEKMASTPGFLDSHIPTYRDELEKFRIPKFKIEFGFSVTSVLDRLGLRSMSMYHKACVEIDEEGAEAAAATADGDCGCSLDFVEPPKKIDFVADHPFLFLIREEKTGTVLFVGQIFDPSGPCSGSNSDSDDY", "length": 385 }, "evidence": [ { "id": "P13909", "url": "https://omabrowser.org/oma/group/P13909/", "database": "OMA" } ], "glygen_name": "Arabidopsis", "common_name": "Mouse-ear cress" } ], "go_annotation": { "categories": [ { "name": "Biological Process", "total": 5, "go_terms": [ { "name": "negative regulation of vascular wound healing", "id": "GO:0061044", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0061044", "evidence": [ { "database": "UniProtKB", "id": "P13909", "url": "https://www.uniprot.org/uniprotkb/P13909" } ], "pmid": "" }, { "name": "negative regulation of plasminogen activation", "id": "GO:0010757", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0010757", "evidence": [ { "database": "UniProtKB", "id": "P13909", "url": "https://www.uniprot.org/uniprotkb/P13909" } ], "pmid": "" }, { "name": "negative regulation of blood coagulation", "id": "GO:0030195", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030195", "evidence": [ { "database": "UniProtKB", "id": "P13909", "url": "https://www.uniprot.org/uniprotkb/P13909" } ], "pmid": "" }, { "name": "positive regulation of coagulation", "id": "GO:0050820", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0050820", "evidence": [ { "database": "UniProtKB", "id": "P13909", "url": "https://www.uniprot.org/uniprotkb/P13909" } ], "pmid": "" }, { "name": "replicative senescence", "id": "GO:0090399", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0090399", "evidence": [ { "database": "UniProtKB", "id": "P13909", "url": "https://www.uniprot.org/uniprotkb/P13909" } ], "pmid": "" } ] }, { "name": "Molecular Function", "total": 3, "go_terms": 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"uniprot_canonical_ac": "P02721-1", "uniprot_ac": "P02721", "uniprot_id": "ATP5J_BOVIN", "mass": { "chemical_mass": 12532.0, "monoisotopic_mass": 12532.0 }, "refseq": { "ac": "NP_777142", "name": "ATP synthase peripheral stalk subunit F6, mitochondrial", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_777142" }, "gene_names": [ { "name": "ATP5PF", "type": "recommended", "evidence": [ { "id": "P02721", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P02721" } ] }, { "name": "ATP5J", "type": "synonym", "evidence": [ { "id": "NP_777142", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_777142" }, { "id": "P02721", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P02721" } ] }, { "name": "ATP5PF", "type": "synonym", "evidence": [ { "id": "NP_777142", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_777142" } ] } ], "protein_names": [ { "name": "ATP synthase peripheral stalk subunit F6, mitochondrial", "type": "recommended", "evidence": [ { "id": "P02721", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P02721/entry#names_and_taxonomy" } ] }, { "name": "ATP synthase peripheral stalk subunit F6, mitochondrial", "type": "synonym", "evidence": [ { "id": "NP_777142", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_777142" } ] }, { "name": "ATP synthase peripheral stalk subunit F6", "type": "synonym", "evidence": [ { "id": "P02721", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P02721/entry#names_and_taxonomy" } ] }, { "name": "ATP synthase, H+ transporting, mitochondrial F0 complex, subunit F6", "type": "synonym", "evidence": [ { "id": "NP_777142", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_777142" } ] }, { "name": "ATP synthase, H+ transporting, mitochondrial Fo complex subunit F6", "type": "synonym", "evidence": [ { "id": "NP_777142", "database": "RefSeq", "url": 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ATP synthase complex consist of a soluble F(1) head domain - the catalytic core - and a membrane F(1) domain - the membrane proton channel. These two domains are linked by a central stalk rotating inside the F(1) region and a stationary peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation. In vivo, can only synthesize ATP although its ATP hydrolase activity can be activated artificially in vitro. Part of the complex F(0) domain. 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"https://www.uniprot.org/uniprotkb/F6RRD7/entry#names_and_taxonomy" } ] }, { "name": "3.1.3.16", "type": "synonym", "evidence": [ { "id": "F6RRD7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F6RRD7/entry#names_and_taxonomy" } ] }, { "name": "RNA polymerase II-associated protein 2", "type": "synonym", "evidence": [ { "id": "F6RRD7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F6RRD7/entry#names_and_taxonomy" } ] }, { "name": "putative RNA polymerase II subunit B1 CTD phosphatase RPAP2", "type": "synonym", "evidence": [ { "id": "NP_001096736", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001096736" } ] } ], "function": [ { "annotation": "Protein phosphatase that displays CTD phosphatase activity and regulates transcription of snRNA genes. Recognizes and binds phosphorylated 'Ser-7' of the C-terminal heptapeptide repeat domain (CTD) of the largest RNA polymerase II subunit POLR2A, and mediates dephosphorylation of 'Ser-5' of the CTD, thereby promoting transcription of snRNA genes (By similarity). Downstream of EIF2AK3/PERK, dephosphorylates ERN1, a sensor for the endoplasmic reticulum unfolded protein response (UPR), to abort failed ER-stress adaptation and trigger apoptosis (By similarity).", "evidence": [ { "database": "UniProtKB", "id": "F6RRD7", "url": "https://www.uniprot.org/uniprotkb/F6RRD7#function" }, { "database": "UniProtKB", "id": "Q8IXW5", "url": "https://www.uniprot.org/uniprotkb/Q8IXW5#function" }, { "database": "UniProtKB", "id": "A0A3Q1M7P6", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1M7P6#function" }, { "database": "UniProtKB", "id": "ARBA00045547", "url": "https://www.uniprot.org/uniprotkb/ARBA00045547#function" }, { "database": "UniProtKB", "id": "A0A3Q1NG49", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1NG49#function" }, { "database": "UniProtKB", "id": "A0A3Q1LQS6", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1LQS6#function" }, { "database": "UniProtKB", "id": "A0A3Q1LZG0", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1LZG0#function" }, { "database": "UniProtKB", "id": "A0A3Q1MCX5", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1MCX5#function" }, { "database": "UniProtKB", "id": "A0A3Q1MKH1", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1MKH1#function" }, { "database": "UniProtKB", "id": "A0A3Q1MPV2", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1MPV2#function" }, { "database": "UniProtKB", "id": "A0A3Q1NIY5", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1NIY5#function" }, { "database": "UniProtKB", "id": "A0A452DJA7", "url": "https://www.uniprot.org/uniprotkb/A0A452DJA7#function" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Bos taurus", "taxid": 9913, "evidence": [ { "database": "UniProtKB", "id": "F6RRD7", "url": "https://www.uniprot.org/uniprotkb/F6RRD7" } ], "common_name": "Bovine", "glygen_name": "Bovine", "reference_species": "Bos taurus [9913]" } ], "gene": [ { "name": "RPAP2", "url": "https://www.uniprot.org/uniprotkb/F6RRD7", "locus": { "chromosome": "3", "start_pos": 51008763, "end_pos": 51122203, "strand": "+", "evidence": [ { "database": "Ensembl Gene", "id": "ENSBTAG00000018739", "url": "https://www.ensembl.org/id/ENSBTAG00000018739" } ] } } ], "crossref": [ { "id": "F6RRD7", "url": "https://alphafold.ebi.ac.uk/entry/F6RRD7", "database": "AlphaFoldDB", "categories": [] }, { "id": "ENSBTAG00000018739", "url": "https://bgee.org/?page=gene&gene_id=ENSBTAG00000018739", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "529184", "url": "https://www.ncbi.nlm.nih.gov/gene/529184", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR007308", "url": "https://www.ebi.ac.uk/interpro/entry/IPR007308", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR038534", "url": "https://www.ebi.ac.uk/interpro/entry/IPR038534", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR039693", "url": "https://www.ebi.ac.uk/interpro/entry/IPR039693", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "bta:529184", "url": "https://www.genome.jp/dbget-bin/www_bget?bta:529184", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "A0A3Q1LQS6", "url": "https://www.orthodb.org/?gene=A0A3Q1LQS6", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A3Q1LZG0", "url": "https://www.orthodb.org/?gene=A0A3Q1LZG0", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A3Q1M7P6", "url": "https://www.orthodb.org/?gene=A0A3Q1M7P6", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A3Q1MCX5", "url": "https://www.orthodb.org/?gene=A0A3Q1MCX5", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A3Q1MKH1", "url": "https://www.orthodb.org/?gene=A0A3Q1MKH1", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A3Q1MPV2", "url": "https://www.orthodb.org/?gene=A0A3Q1MPV2", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A3Q1NG49", "url": "https://www.orthodb.org/?gene=A0A3Q1NG49", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A3Q1NIY5", "url": "https://www.orthodb.org/?gene=A0A3Q1NIY5", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "F6RRD7", "url": "https://www.orthodb.org/?gene=F6RRD7", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR14732", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR14732", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR14732:SF0", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR14732:SF0", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF04181", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF04181", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "R-BTA-6807505", "url": "https://www.reactome.org/PathwayBrowser/#R-BTA-6807505", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "NP_001096736", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001096736", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "20629", "url": "https://www.rhea-db.org/rhea/20629", "database": "Rhea", "categories": [ "Enzyme and Pathway" ] }, { "id": "47004", "url": "https://www.rhea-db.org/rhea/47004", "database": "Rhea", "categories": [ "Enzyme and Pathway" ] }, { "id": "A0A3Q1LQS6", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1LQS6", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A3Q1LQS6-1", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1LQS6-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A3Q1LZG0", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1LZG0", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A3Q1LZG0-1", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1LZG0-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A3Q1M7P6", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1M7P6", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A3Q1M7P6-1", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1M7P6-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A3Q1MCX5", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1MCX5", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A3Q1MCX5-1", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1MCX5-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A3Q1MKH1", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1MKH1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A3Q1MKH1-1", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1MKH1-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A3Q1MPV2", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1MPV2", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A3Q1MPV2-1", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1MPV2-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A3Q1NG49", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1NG49", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A3Q1NG49-1", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1NG49-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A3Q1NIY5", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1NIY5", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A3Q1NIY5-1", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1NIY5-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A452DJA7", "url": "https://www.uniprot.org/uniprotkb/A0A452DJA7", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A452DJA7-1", "url": "https://www.uniprot.org/uniprotkb/A0A452DJA7-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "F6RRD7", "url": "https://www.uniprot.org/uniprotkb/F6RRD7", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "F6RRD7-1", "url": "https://www.uniprot.org/uniprotkb/F6RRD7-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MADWVGPCSAGRKARRSRASRDVAGTKQTSALNQEDASQRKAELEAAVRKKIEFERKALHIVEQLLEENISEEFLRECGKFITPAHYSDVVDERSIIKLCGYPLCQNKLGIVPKQKYKISTKTNKVYDITERKCFCSNFCYKASKFFEAQIPKSPVWIREEERHPDFQLLQDGQSGPSGEEIQLCSKAIKTSDIDSPGHFEKHYESSSSSSHSDSSSDNEQDFVSSILPGNRPNATRPQLHEKSIMKKKAGQKVNSQHESKEQTVVDVIEQLGNCRLDNQEKATACELPLQNVNTQISSNSSLQKKLEASEISDIKYSSSKVTLVGISKKSAEHFKRKFAKSNQVSGSASSSLQVCPEIAKANLLKALKETLIEWKTEETLRFLYGQNYASVCLKSSSTPLVKEEELDEDDMNSDPDSHSPALQELNSLDESLPFRASDTAIKPLPSYENLKKETETLNLRIREFYRGRYVLNEETTKSQDSEEHDPTFPLIDSSSQNQIRKRIVLEKLNKVLPGLLGPLQITLGDIYTQLKNLVHTFRLTNRNIIHKPAEWTLIALVLLSILTSTLGIQKLSQENVMFTQFMTTLLEELHLKNEDLESLTIIFRTSC", "length": 608, "header": "sp|F6RRD7-1|RPAP2_BOVIN Isoform 1 of Putative RNA polymerase II subunit B1 CTD phosphatase RPAP2 OS=Bos taurus OX=9913 GN=RPAP2 PE=2 SV=1 CANONICAL=F6RRD7-1" }, "isoforms": [ { "isoform_ac": "A0A3Q1LQS6-1", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1LQS6/entry", "sequence": { "sequence": "MADWVGPCSAGRKARRSRASRDVAGTKQTSALIQEDASQRKAELEAAVRKKIEFERKALHIVEQLLEENISEEFLRECGKFITPAHYSDVVDERSIIKLCGYPLCQNKLGIVPKQKYKISTKTNKVYDITERKCFCSNFCYKASKFFEAQIPKSPVWIREEERHPDFQLLQDGQSGPSGEEIQLCSKAIKTSDIDSPGHFEKHYESSSSSSHSDSSSDNEQDFVSSILPGNRPNATRPQLHEKSIMKKKAGQKVNSQHESKEQTVVDVIEQLGNCRLDNQEKATACELPLQNVNTQISSNSSLQKKLEASEISDIKYSSSKVTLVGISKKSAEHFKRKFAKSNQVSGSASSSLQVCPEIAKANLLKALKETLIEWKTEETLRFLYGQNYASVCLKSSSTPLVKEEELDEDDMNSDPDSHSPALQELNSLDESLPFRASDTAIKPLPSYENLKKETETLNLRIREFYRGRYVLNEETTKSQDSEEHDPTFPLIDSSSQNQIRKRIVLEKLNKVLPGLLGPLQITLGDIYTQLKNLVHTFRLTSTLGIQKLSQENVMFTQFMTTLLEELHLKNEDLESLTIIFRTSC", "length": 585, "header": "tr|A0A3Q1LQS6-1|A0A3Q1LQS6_BOVIN Computationally mapped isoform of RNA polymerase II subunit B1 CTD phosphatase RPAP2 homolog OS=Bos taurus OX=9913 GN=RPAP2 PE=3 SV=2 CANONICAL=F6RRD7-1" }, "locus": { "chromosome": "3", "start_pos": 51122179, "end_pos": 51040055, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000078006.2", "url": "https://www.ensembl.org/id/ENSBTAT00000078006.2" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000057362.2", "url": "https://www.ensembl.org/id/ENSBTAP00000057362.2" } ] } }, { "isoform_ac": "A0A3Q1LZG0-1", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1LZG0/entry", "sequence": { "sequence": "AFICVGPTEADRSSLVPPRLKAELEAAVRKKIEFERKALHIVEQLLEENISEEFLRECGKFITPAHYSDVVDERSIIKLCGYPLCQNKLGIVPKQKYKISTKTNKVYDITERKCFCSNFCYKASKFFEAQIPKSPVWIREEERHPDFQLLQDGQSGPSGEEIQLCSKAIKTSDIDSPGHFEKHYESSSSSSHSDSSSDNEQDFVSSILPGNRPNATRPQLHEKSIMKKKAGQKVNSQHESKEQTVVDVIEQLGNCRLDNQEKATACELPLQNVNTQISSNSSLQKKLEASEISDIKYSSSKVTLVGISKKSAEHFKRKFAKSNQVSGSASSSLQVCPEIAKANLLKALKETLIEWKTEETLRFLYGQNYASVCLKSSSTPLVKEEELDEDDMNSDPDSHSPALQELNSLDESLPFRASDTAIKPLPSYENLKKETETLNLRIREFYRGRYVLNEETTKSQDSEEHDPTFPLIDSSSQNQIRKRIVLEKLNKVLPGLLGPLQITLGDIYTQLKNLVHTFRLTNRNIIHKPAEWTLIALVLLSILTSTLGIQKLSQENVMFTQFMTTLLEELHLKNEDLESLTIIFRTSC", "length": 588, "header": "tr|A0A3Q1LZG0-1|A0A3Q1LZG0_BOVIN Computationally mapped isoform of RNA polymerase II subunit B1 CTD phosphatase RPAP2 homolog OS=Bos taurus OX=9913 GN=RPAP2 PE=3 SV=2 CANONICAL=F6RRD7-1" }, "locus": { "chromosome": "3", "start_pos": 51116871, "end_pos": 51040055, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000084772.2", "url": "https://www.ensembl.org/id/ENSBTAT00000084772.2" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000063035.2", "url": "https://www.ensembl.org/id/ENSBTAP00000063035.2" } ] } }, { "isoform_ac": "A0A3Q1M7P6-1", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1M7P6/entry", "sequence": { "sequence": "MADWVGPCSAGRKARRSRASRDVAGTKQTSALIQEDASQRKAELEAAVRKKIEFERKALHIVEQLLEENISEEFLRECGKFITPAHYSDVVDERSIIKLCGYPLCQNKLGIVPKQKYKISTKTNKVYDITERKCFCSNFCYKASKFFEAQIPKSPVWIREEERHPDFQLLQDGQSGPSGEEIQLCSKAIKTSDIDSPGHFEKHYESSSSSSHSDSSSDNEQDFVSSILPGNRPNATRPQLHEKSIMKKKAGQKVNSQHESKEQTVVDVIEQLGNCRLDNQEKATACELPLQNVNTQISSNSSLQKKLEASEISDIKYSSSKVTLVGISKKSAEHFKRKFAKSNQVSGSASSSLQVCPEIAKANLLKALKETLIEWKTEETLRFLYGQNYASVCLKSSSTPLVKEEELDEDDMNSDPDSHSPALQELNSLDESLPFRASDTAIKPLPSYENLKKETETLNLRIREFYRGRYVLNEETTKSQDSEEHDPTFPLIDSSSQNQIRKRIVLEKLNKVLPGLLGPLQITLGDIYTQLKNLVHTFRLTNRNIIHKPAEWTLIALVLLSMFVQNEAGQRLTELCQENTLVIANNTLFQQHKR", "length": 594, "header": "tr|A0A3Q1M7P6-1|A0A3Q1M7P6_BOVIN Computationally mapped isoform of RNA polymerase II subunit B1 CTD phosphatase RPAP2 homolog OS=Bos taurus OX=9913 GN=RPAP2 PE=3 SV=2 CANONICAL=F6RRD7-1" }, "locus": { "chromosome": "3", "start_pos": 51122179, "end_pos": 51060548, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000082817.2", "url": "https://www.ensembl.org/id/ENSBTAT00000082817.2" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000069870.2", "url": "https://www.ensembl.org/id/ENSBTAP00000069870.2" } ] } }, { "isoform_ac": "A0A3Q1MCX5-1", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1MCX5/entry", "sequence": { "sequence": "MADWVGPCSAGRKARRSRASRDVAGTKQTSALIQEDASQRKAELEAAVRKKIEFERKALHIVEQLLEENISEEFLRECGKFITPAHYSDVVDERSIIKLCGYPLCQNKLGIVPKQKYKISTKTNKVYDITERKCFCSNFCYKASKFFEAQIPKSPVWIREEERHPDFQLLQDGQSGPSGEEIQLCSKAIKTSDIDSPGHFEKHYESSSSSSHSDSSSDNEQDFVSSILPGNRPNATRPQLHEKSIMKKKAGQKVNSQHESKEQTVVDVIEQLGNCRLDNQEKATACELPLQNVNTQISSNSSLQKKLEASEISDIKYSSSKVTLVGISKKSAEHFKRKFAKSNQVSGSASSSLQVCPEIAKANLLKALKETLIEWKTEETLRFLYGQNYASVCLKSSSTPLVKEEELDEDDMNSDPDSHSPALQELNSLDESLPFRASDTAIKPLPSYENLKKETETLNLRIREFYRGRYVLNEETTKSQDSEEHDPTFPLIDSSSQNQIRKRIVLEKLNKVLPGLLGPLQITLGDIYTQLKNLVHTFRLTNRNIIHKPAEWTLIALVLLSMPRDSQESSRTPLKSIDSSALSFLYGPALTSMHDYWKNLRFD", "length": 603, "header": "tr|A0A3Q1MCX5-1|A0A3Q1MCX5_BOVIN Computationally mapped isoform of RNA polymerase II subunit B1 CTD phosphatase RPAP2 homolog OS=Bos taurus OX=9913 GN=RPAP2 PE=3 SV=2 CANONICAL=F6RRD7-1" }, "locus": { "chromosome": "3", "start_pos": 51122179, "end_pos": 51055290, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000071401.2", "url": "https://www.ensembl.org/id/ENSBTAT00000071401.2" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000066661.2", "url": "https://www.ensembl.org/id/ENSBTAP00000066661.2" } ] } }, { "isoform_ac": "A0A3Q1MKH1-1", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1MKH1/entry", "sequence": { "sequence": "MADWVGPCSAGRKARRSRASRDVAGTKQTSALIQEDASQRKAELEAAVRKKIEFERKALHIVEQLLEENISEEFLRECGKFITPAHYSDVVDERSIIKLCGYPLCQNKLGIVPKQKYKISTKTNKVYDITERKCFCSNFCYKASKFFEAQIPKSPVWIREEERHPDFQLLQDGQSGPSGEEIQLCSKAIKTSDIDSPGHFEKHYESSSSSSHSDSSSDNEQDFVSSILPGNRPNATRPQLHEKSIMKKKAGQKVNSQHESKEQTVVDVIEQLGNCRLDNQEKATACELPLQNVNTQISSNSSLQKKLEASEISDIKYSSSKVTLVGISKKSAEHFKRKFAKSNQVSGSASSSLQVCPEIAKANLLKALKETLIEWKTEETLRFLYGQNYASVCLKSSSTPLVKEEELDEDDMNSDPDSHSPALQELNSLDESLPFRASDTAIKPLPSYENLKKETETLNLRIREFYRGRYVLNEETTKSQDSEEHDPTFPLIDSSSQNQIRKRIVLEKLNKVLPGLLGPLQITLGDIYTQLKNLVHTFRLTNRNIIHKPAEWTLIALVLLSMIYHKPGVPHLMNRQNPAHCQQRKIYLKHKRF", "length": 593, "header": "tr|A0A3Q1MKH1-1|A0A3Q1MKH1_BOVIN Computationally mapped isoform of RNA polymerase II subunit B1 CTD phosphatase RPAP2 homolog OS=Bos taurus OX=9913 GN=RPAP2 PE=3 SV=2 CANONICAL=F6RRD7-1" }, "locus": { "chromosome": "3", "start_pos": 51122179, "end_pos": 51008787, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000072884.2", "url": "https://www.ensembl.org/id/ENSBTAT00000072884.2" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000071369.2", "url": "https://www.ensembl.org/id/ENSBTAP00000071369.2" } ] } }, { "isoform_ac": "A0A3Q1MPV2-1", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1MPV2/entry", "sequence": { "sequence": "MADWVGPCSAGRKARRSRASRDVAGTKQTSALIQEDASQRKAELEAAVRKKIEFERKALHIVEQLLEENISEEFLRECGKFITPAHYSDVVDERSIIKLCGYPLCQNKLGIVPKQKYKISTKTNKVYDITERKCFCSNFCYKASKFFEAQIPKSPVWIREEERHPDFQLLQDGQSGPSGEEIQLCSKAIKTSDIDSPGHFEKHYESSSSSSHSDSSSDNEQDFVSSILPGNRPNATRPQLHEKSIMKKKAGQKVNSQHESKEQTVVDVIEQLGNCRLDNQEKATACELPLQNVNTQISSNSSLQKKLEASEISDIKYSSSKVTLVGISKKSAEHFKRKFAKSNQVSGSASSSLQVCPEIAKANLLKALKETLIEWKTEETLRFLYGQNYASVCLKSSSTPLVKEEELDEDDMNSDPDSHSPALQELNSLDESLPFRASDTAIKPLPSYENLKKETETLNLRIREFYRGRYVLNEETTKSQDSEEHDPTFPLIDSSSQNQIRKRIVLEKLNKVLPGLLGPLQITLGDIYTQLKNLVHTFRLTNRNIIHKPAEWTLIALVLLSMKSWPQLPVSSPKCPA", "length": 577, "header": "tr|A0A3Q1MPV2-1|A0A3Q1MPV2_BOVIN Computationally mapped isoform of RNA polymerase II subunit B1 CTD phosphatase RPAP2 homolog OS=Bos taurus OX=9913 GN=RPAP2 PE=3 SV=2 CANONICAL=F6RRD7-1" }, "locus": { "chromosome": "3", "start_pos": 51122179, "end_pos": 51041494, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000072015.2", "url": "https://www.ensembl.org/id/ENSBTAT00000072015.2" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000073965.2", "url": "https://www.ensembl.org/id/ENSBTAP00000073965.2" } ] } }, { "isoform_ac": "A0A3Q1NG49-1", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1NG49/entry", "sequence": { "sequence": "MADWVGPCSAGRKARRSRASRDVAGTKQTSALIQEDASQRKAELEAAVRKKIEFERKALHIVEQLLEENISEEFLRECGKFITPAHYSDVVDERSIIKLCGYPLCQNKLGIVPKQKYKISTKTNKVYDITERKCFCSNFCYKASKFFEAQIPKSPVWIREEERHPDFQLLQDGQSGPSGEEIQLCSKAIKTSDIDSPGHFEKHYESSSSSSHSDSSSDNEQDFVSSILPGNRPNATRPQLHEKSIMKKKAGQKVNSQHESKEQTVVDVIEQLGNCRLDNQEKATACELPLQNVNTQISSNSSLQKKLEASEISDIKYSSSKVTLVGISKKSAEHFKRKFAKSNQVSGSASSSLQVCPEIAKANLLKALKETLIEWKTEETLRFLYGQNYASVCLKSSSTPLVKEEELDEDDMNSDPDSHSPALQELNSLDESLPFRASDTAIKPLPSYENLKKETETLNLRIREFYRGRYVLNEETTKSQDSEEHDPTFPLIDSSSQNQIRKRIVLEKLNKVLPGLLGPLQITLGDIYTQLKNLVHTFRLTNRNIIHKPAEWTLIALVLLSIRKWQPTPVFLPGESQGRGSLVGCCLWGRTESDTTEAT", "length": 599, "header": "tr|A0A3Q1NG49-1|A0A3Q1NG49_BOVIN Computationally mapped isoform of RNA polymerase II subunit B1 CTD phosphatase RPAP2 homolog OS=Bos taurus OX=9913 GN=RPAP2 PE=3 SV=2 CANONICAL=F6RRD7-1" }, "locus": { "chromosome": "3", "start_pos": 51122179, "end_pos": 51049399, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000080116.2", "url": "https://www.ensembl.org/id/ENSBTAT00000080116.2" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000070749.2", "url": "https://www.ensembl.org/id/ENSBTAP00000070749.2" } ] } }, { "isoform_ac": "A0A3Q1NIY5-1", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1NIY5/entry", "sequence": { "sequence": "MADWVGPCSAGRKARRSRASRDVAGTKQTSALIQEDASQRKAELEAAVRKKIEFERKALHIVEQLLEENISEEFLRECGKFITPAHYSDVVDERSIIKLCGYPLCQNKLGIVPKQKYKISTKTNKVYDITERKCFCSNFCYKASKFFEAQIPKSPVWIREEERHPDFQLLQDGQSGPSGEEIQLCSKAIKTSDIDSPGHFEKHYESSSSSSHSDSSSDNEQDFVSSILPGNRPNATRPQLHEKSIMKKKAGQKVNSQHESKEQTVVDVIEQLGNCRLDNQEKATACELPLQNVNTQISSNSSLQKKLEASEISDIKYSSSKVTLVGISKKSAEHFKRKFAKSNQVSGSASSSLQVCPEIAKANLLKALKETLIEWKTEETLRFLYGQNYASVCLKSSSTPLVKEEELDEDDMNSDPDSHSPALQELNSLDESLPFRASDTAIKPLPSYENLKKETETLNLRIREFYRGRYVLNEETTKSQDSEEHDPTFPLIDSSSQNQIRKRIVLEKLNKVLPGLLGPLQITLGDIYTQLKNLVHTFRLTNRNIIHKPAEWTLIALVLLSIRVRLSATP", "length": 570, "header": "tr|A0A3Q1NIY5-1|A0A3Q1NIY5_BOVIN Computationally mapped isoform of RNA polymerase II subunit B1 CTD phosphatase RPAP2 homolog OS=Bos taurus OX=9913 GN=RPAP2 PE=3 SV=2 CANONICAL=F6RRD7-1" }, "locus": { "chromosome": "3", "start_pos": 51122179, "end_pos": 51068088, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000067088.2", "url": "https://www.ensembl.org/id/ENSBTAT00000067088.2" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000072035.2", "url": "https://www.ensembl.org/id/ENSBTAP00000072035.2" } ] } }, { "isoform_ac": "A0A452DJA7-1", "url": "https://www.uniprot.org/uniprotkb/A0A452DJA7/entry", "sequence": { "sequence": "MADWVGPCSAGRKARRSRASRDVAGTKQTSALIQEDASQRKAELEAAVRKKIEFERKALHIVEQLLEENISEEFLRECGKFITPAHYSDVVDERSIIKLCGYPLCQNKLGIVPKQKYKISTKTNKVYDITERKCFCSNFCYKASKFFEAQIPKSPVWIREEERHPDFQLLQDGQSGPSGEEIQLCSKAIKTSDIDSPGHFEKHYESSSSSSHSDSSSDNEQDFVSSILPGNRPNATRPQLHEKSIMKKKAGQKVNSQHESKEQTVVDVIEQLGNCRLDNQEKATACELPLQNVNTQISSNSSLQKKLEASEISDIKYSSSKVTLVGISKKSAEHFKRKFAKSNQVSGSASSSLQVCPEIAKANLLKALKETLIEWKTEETLRFLYGQNYASVCLKSSSTPLVKEEELDEDDMNSDPDSHSPALQELNSLDESLPFRASDTAIKPLPSYENLKKETETLNLRIREFYRGRYVLNEETTKSQDSEEHDPTFPLIDSSSQNQIRKRIVLEKLNKVLPGLLGPLQITLGDIYTQLKNLVHTFRLTNRNIIHKPAEWTLIALVLLSILTSTLGIQKLSQENVMFTQFMTTLLEELHLKNEDLESLTIIFRTSC", "length": 608, "header": "tr|A0A452DJA7-1|RPAP2_BOVIN Computationally mapped isoform of Putative RNA polymerase II subunit B1 CTD phosphatase RPAP2 OS=Bos taurus OX=9913 GN=RPAP2 PE=2 SV=1 CANONICAL=F6RRD7-1" }, "locus": { "chromosome": "3", "start_pos": 51122179, "end_pos": 51040055, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000044283.4", "url": "https://www.ensembl.org/id/ENSBTAT00000044283.4" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000041791.4", "url": "https://www.ensembl.org/id/ENSBTAP00000041791.4" } ] } }, { "isoform_ac": "F6RRD7-1", "url": "https://www.uniprot.org/uniprotkb/F6RRD7/entry#F6RRD7-1", "sequence": { "sequence": "MADWVGPCSAGRKARRSRASRDVAGTKQTSALNQEDASQRKAELEAAVRKKIEFERKALHIVEQLLEENISEEFLRECGKFITPAHYSDVVDERSIIKLCGYPLCQNKLGIVPKQKYKISTKTNKVYDITERKCFCSNFCYKASKFFEAQIPKSPVWIREEERHPDFQLLQDGQSGPSGEEIQLCSKAIKTSDIDSPGHFEKHYESSSSSSHSDSSSDNEQDFVSSILPGNRPNATRPQLHEKSIMKKKAGQKVNSQHESKEQTVVDVIEQLGNCRLDNQEKATACELPLQNVNTQISSNSSLQKKLEASEISDIKYSSSKVTLVGISKKSAEHFKRKFAKSNQVSGSASSSLQVCPEIAKANLLKALKETLIEWKTEETLRFLYGQNYASVCLKSSSTPLVKEEELDEDDMNSDPDSHSPALQELNSLDESLPFRASDTAIKPLPSYENLKKETETLNLRIREFYRGRYVLNEETTKSQDSEEHDPTFPLIDSSSQNQIRKRIVLEKLNKVLPGLLGPLQITLGDIYTQLKNLVHTFRLTNRNIIHKPAEWTLIALVLLSILTSTLGIQKLSQENVMFTQFMTTLLEELHLKNEDLESLTIIFRTSC", "length": 608, "header": "sp|F6RRD7-1|RPAP2_BOVIN Isoform 1 of Putative RNA polymerase II subunit B1 CTD phosphatase RPAP2 OS=Bos taurus OX=9913 GN=RPAP2 PE=2 SV=1 CANONICAL=F6RRD7-1" }, "locus": {} } ], "glycosylation": [], "phosphorylation": [ { "start_pos": 216, "end_pos": 216, "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "residue": "Ser", "comment": "Phosphoserine", "evidence": [ { "database": "UniProtKB", "id": "F6RRD7", "url": "https://www.uniprot.org/uniprotkb/F6RRD7" } ], "site_lbl": "Ser216" }, { "start_pos": 432, "end_pos": 432, "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "residue": "Ser", "comment": "Phosphoserine", "evidence": [ { "database": "UniProtKB", "id": "F6RRD7", "url": "https://www.uniprot.org/uniprotkb/F6RRD7" } ], "site_lbl": "Ser432" }, { "start_pos": 479, "end_pos": 479, "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "residue": "Ser", "comment": "Phosphoserine", "evidence": [ { "database": "UniProtKB", "id": "F6RRD7", "url": "https://www.uniprot.org/uniprotkb/F6RRD7" } ], "site_lbl": "Ser479" }, { "start_pos": 9, "end_pos": 9, "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "residue": "Ser", "comment": "Phosphoserine", "evidence": [ { "database": "UniProtKB", "id": "F6RRD7", "url": "https://www.uniprot.org/uniprotkb/F6RRD7" } ], "site_lbl": "Ser9" } ], "glycation": [], "keywords": [ "enzyme" ], "publication": [ { "title": "A whole-genome assembly of the domestic cow, Bos taurus.", "journal": "Genome Biol.", "date": "2009", "authors": "Zimin Aleksey V, Delcher Arthur L, Florea Liliana, Kelley David R, Schatz Michael C, Puiu Daniela, Hanrahan Finnian, Pertea Geo, Van Tassell Curtis P, Sonstegard Tad S, Mar\u00e7ais Guillaume, Roberts Michael, Subramanian Poorani, Yorke James A, Salzberg Steven L", "evidence": [ { "database": "UniProtKB", "id": "F6RRD7", "url": "https://www.uniprot.org/uniprotkb/F6RRD7" } ], "reference": [ { "type": "PubMed", "id": "19393038", "url": "https://glygen.org/publication/PubMed/19393038" } ] } ], "pathway": [ { "id": "bta:529184", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?bta:529184", "resource": "KEGG Pathway" }, { "id": "R-BTA-6807505", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-BTA-6807505", "resource": "Reactome", "description": "RNA polymerase II transcribes snRNA genes" } ], "orthologs": [], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 5, "go_terms": [ { "name": "transcription preinitiation complex", "id": "GO:0097550", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0097550", "evidence": [ { "database": "UniProtKB", "id": "F6RRD7", "url": "https://www.uniprot.org/uniprotkb/F6RRD7" } ], "pmid": "" }, { "name": "nucleus", "id": "GO:0005634", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005634", "evidence": [ { "database": "UniProtKB", "id": "F6RRD7", "url": "https://www.uniprot.org/uniprotkb/F6RRD7" } ], "pmid": "" }, { "name": "cytoplasm", "id": "GO:0005737", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005737", "evidence": [ { "database": "UniProtKB", "id": "F6RRD7", "url": "https://www.uniprot.org/uniprotkb/F6RRD7" } ], "pmid": "" }, { "name": "nucleolus", "id": "GO:0005730", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005730", "evidence": [ { "database": "UniProtKB", "id": "F6RRD7", "url": "https://www.uniprot.org/uniprotkb/F6RRD7" } ], "pmid": "" }, { "name": "cytosol", "id": "GO:0005829", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005829", "evidence": [ { "database": "UniProtKB", "id": "F6RRD7", "url": "https://www.uniprot.org/uniprotkb/F6RRD7" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 3, "go_terms": [ { "name": "snRNA transcription", "id": "GO:0009301", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0009301", "evidence": [ { "database": "UniProtKB", "id": "F6RRD7", "url": "https://www.uniprot.org/uniprotkb/F6RRD7" } ], "pmid": "" }, { "name": "PERK-mediated unfolded protein response", "id": "GO:0036499", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0036499", "evidence": [ { "database": "UniProtKB", "id": "F6RRD7", "url": "https://www.uniprot.org/uniprotkb/F6RRD7" } ], "pmid": "" }, { "name": "DNA-templated transcription", "id": "GO:0006351", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006351", "evidence": [ { "database": "UniProtKB", "id": "F6RRD7", "url": "https://www.uniprot.org/uniprotkb/F6RRD7" } ], "pmid": "" } ] }, { "name": "Molecular Function", "total": 4, "go_terms": [ { "name": "zinc ion binding", "id": "GO:0008270", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008270", "evidence": [ { "database": "UniProtKB", "id": "F6RRD7", "url": "https://www.uniprot.org/uniprotkb/F6RRD7" } ], "pmid": "" }, { "name": "protein serine/threonine phosphatase activity", "id": "GO:0004722", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0004722", "evidence": [ { "database": "UniProtKB", "id": "F6RRD7", "url": "https://www.uniprot.org/uniprotkb/F6RRD7" } ], "pmid": "" }, { "name": "RNA polymerase core enzyme binding", "id": "GO:0043175", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0043175", "evidence": [ { "database": "UniProtKB", "id": "F6RRD7", "url": "https://www.uniprot.org/uniprotkb/F6RRD7" } ], "pmid": "" }, { "name": "RNA polymerase II CTD heptapeptide repeat phosphatase activity", "id": "GO:0008420", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008420", "evidence": [ { "database": "UniProtKB", "id": "F6RRD7", "url": "https://www.uniprot.org/uniprotkb/F6RRD7" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 234, "end_pos": 236, "annotation": "n_glycosylation_sequon" }, { "start_pos": 300, "end_pos": 302, "annotation": "n_glycosylation_sequon" }, { "start_pos": 69, "end_pos": 71, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [ { "id": "20629", "name": "", "equation": "O-phospho-L-seryl-[protein] + H2O = L-seryl-[protein] + phosphate", "summary": "", "cellular_location": "", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [ "E1BEW5-1", "A0AAA9TV14-1", "A0AAA9S745-1", "A0A3Q1MV48-1", "F1ME76-1", "E1BAB2-1", "E1BBD9-1", "A0A3Q1N5B2-1", "F1MBQ1-1", "A0AAA9RTM1-1", "A0AAF6YJP2-1", "P48452-1", "F1MI99-1", "G3N3B3-1", "O62830-1", "Q0IIF0-1", "A5PJZ2-1", "Q17QJ3-1", "F6RRD7-1", "Q5BIP9-1", "A0AAA9TT76-1", "A6H772-1", "O62829-1", "P61287-1", "A0AAA9U0H6-1", "Q3ZBF9-1", "Q3SWW9-1", "Q3T0E7-1", "P0C591-1", "P67774-1", "Q0IID7-1", "Q0P594-1", "Q1RMV9-1", "Q2KJ36-1", "Q2PC20-1", "P79126-1", "Q17QI2-1", "Q17QM8-1", "Q2KJD7-1", "E1B9Y5-1", "Q58DC0-1", "A0AAA9SWY4-1", "A0A3Q1LZA9-1", "A0AAA9S454-1", "A0AAA9SCR0-1", "A0AAA9TD32-1", "A0A3Q1N224-1", "E1BMD4-1", "A0AAF6DLF7-1", "F1N580-1", "F1MQM7-1", "F1MW60-1", "F1N719-1", "E1BF95-1", "E1BIE7-1", "F1MEZ2-1", "F1MM08-1", "A0A3Q1MLC5-1", "A0A3Q1MH98-1", "F1MW70-1", "A0A3Q1MZU1-1" ], "evidence": [ { "id": "20629", "database": "Rhea", "url": "https://www.rhea-db.org/rhea/20629" } ] }, { "id": "47004", "name": "", "equation": "O-phospho-L-threonyl-[protein] + H2O = L-threonyl-[protein] + phosphate", "summary": "", "cellular_location": "", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [ "A0AAF6DLF7-1", "F1MI92-1", "A0A3Q1MV48-1", "E1BEW5-1", "F1ME76-1", "E1BAB2-1", "E1BBD9-1", "A0A3Q1N5B2-1", "A0ABI0P1A3-1", "F1MBQ1-1", "A0AAA9RTM1-1", "G3N3B3-1", "A0AAF6YJP2-1", "P48452-1", "O62829-1", "Q0IIF0-1", "A5PJZ2-1", "Q17QJ3-1", "F6RRD7-1", "Q5BIP9-1", "A0AAA9TT76-1", "Q0P594-1", "A6H772-1", "O62830-1", "P61287-1", "A0AAA9U0H6-1", "Q3SWW9-1", "Q3T0E7-1", "P0C591-1", "P67774-1", "Q0IID7-1", "Q1RMV9-1", "Q2KJ36-1", "P79126-1", "Q17QI2-1", "Q17QM8-1", "Q2KJD7-1", "E1B9Y5-1", "E1BIZ2-1", "F1MI99-1", "F1MP34-1", "F1MEZ2-1", "F1MQM7-1", "F1MM08-1", "F1N719-1", "A0AAA9T455-1", "Q58DC0-1", "A0AAA9SWY4-1", "A0A3Q1LZA9-1", "A0AAA9S454-1", "A0AAA9SCR0-1", "A0AAA9TD32-1", "A0AAA9TV14-1", "A0AAA9S745-1", "F1N580-1", "E1BMD4-1", "E1BF95-1", "E1BIE7-1", "A0A3Q1N224-1", "A0A3Q1MLC5-1", "A0A3Q1MH98-1", "F1MW70-1", "A0A3Q1MZU1-1" ], "evidence": [ { "id": "47004", "database": "Rhea", "url": "https://www.rhea-db.org/rhea/47004" } ] }, { "id": "R-BTA-6810235", "name": "RPAP2 binds RNA polymerase II phosphorylated at serine-7 residues of heptad repeats in the C-terminal domain", "equation": "", "summary": "This event has been computationally inferred from an event that has been demonstrated in another species.

The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.

More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "cellular_location": "nucleoplasm", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [ "A5PJW8-1", "G3MZY8-1", "Q5EAB2-1", "F2Z4J6-1", "F6RRD7-1" ], "evidence": [ { "id": "R-BTA-6810235", "database": "Reactome", "url": "https://www.reactome.org/PathwayBrowser/#R-BTA-6810235" } ] }, { "id": "R-BTA-6814549", "name": "Pre-snRNA transcript initiation, Integrator binding, LEC binding", "equation": "", "summary": "This event has been computationally inferred from an event that has been demonstrated in another species.

The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.

More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "cellular_location": "nucleoplasm", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [ "A5PJW8-1", "G3MZY8-1", "Q5EAB2-1", "F2Z4J6-1", "F6RRD7-1" ], "evidence": [ { "id": "R-BTA-6814549", "database": "Reactome", "url": "https://www.reactome.org/PathwayBrowser/#R-BTA-6814549" } ] }, { "id": "R-BTA-6814555", "name": "Integrator complex processes the 3' end of snRNA", "equation": "", "summary": "This event has been computationally inferred from an event that has been demonstrated in another species.

The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.

More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "cellular_location": "nucleoplasm", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [ "A5PJW8-1", "G3MZY8-1", "Q5EAB2-1", "F2Z4J6-1", "F6RRD7-1", "Q17QI2-1" ], "evidence": [ { "id": "R-BTA-6814555", "database": "Reactome", "url": "https://www.reactome.org/PathwayBrowser/#R-BTA-6814555" } ] }, { "id": "R-BTA-6814559", "name": "Pre-snRNA is elongated and capped with 7-methylguanosine", "equation": "", "summary": "This event has been computationally inferred from an event that has been demonstrated in another species.

The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.

More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "cellular_location": "nucleoplasm", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [ "A5PJW8-1", "G3MZY8-1", "Q5EAB2-1", "F2Z4J6-1", "F6RRD7-1" ], "evidence": [ { "id": "R-BTA-6814559", "database": "Reactome", "url": "https://www.reactome.org/PathwayBrowser/#R-BTA-6814559" } ] }, { "id": "R-BTA-6814885", "name": "CBCAP complex binds 7-methylguanosine cap of snRNA", "equation": "", "summary": "This event has been computationally inferred from an event that has been demonstrated in another species.

The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.

More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "cellular_location": "nucleoplasm", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [ "A5PJW8-1", "G3MZY8-1", "Q5EAB2-1", "F2Z4J6-1", "F6RRD7-1" ], "evidence": [ { "id": "R-BTA-6814885", "database": "Reactome", "url": "https://www.reactome.org/PathwayBrowser/#R-BTA-6814885" } ] } ], "reaction_participants": [], "reaction_enzymes": [ { "uniprot_ac": "A0A3Q1LZA9", "gene_name": "DUSP15", "activity": [ { "ec_number": "3.1.3.16", "activity": "O-phospho-L-threonyl-[protein] + H2O = L-threonyl-[protein] + phosphate.", "evidence": [ { "id": "A0A3Q1LZA9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1LZA9" } ] }, { "ec_number": "3.1.3.48", "activity": "O-phospho-L-tyrosyl-[protein] + H2O = L-tyrosyl-[protein] + phosphate.", "evidence": [ { "id": "A0A3Q1LZA9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1LZA9" } ] }, { "ec_number": "3.1.3.16", "activity": "", "evidence": [ { "id": "A0A3Q1LZA9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1LZA9" } ] }, { "ec_number": "3.1.3.48", "activity": "", "evidence": [ { "id": "A0A3Q1LZA9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1LZA9" } ] } ] }, { "uniprot_ac": "A0A3Q1MH98", "gene_name": "DUSP28", "activity": [ { "ec_number": "3.1.3.16", "activity": "O-phospho-L-threonyl-[protein] + H2O = L-threonyl-[protein] + phosphate.", "evidence": [ { "id": "A0A3Q1MH98", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1MH98" } ] }, { "ec_number": "3.1.3.48", "activity": "O-phospho-L-tyrosyl-[protein] + H2O = L-tyrosyl-[protein] + phosphate.", "evidence": [ { "id": "A0A3Q1MH98", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1MH98" } ] }, { "ec_number": "3.1.3.16", "activity": "", "evidence": [ { "id": "A0A3Q1MH98", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1MH98" } ] }, { "ec_number": "3.1.3.48", "activity": "", "evidence": [ { "id": "A0A3Q1MH98", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1MH98" } ] } ] }, { "uniprot_ac": "A0A3Q1MLC5", "gene_name": "DUSP8", "activity": [ { "ec_number": "3.1.3.16", "activity": "O-phospho-L-threonyl-[protein] + H2O = L-threonyl-[protein] + phosphate.", "evidence": [ { "id": "A0A3Q1MLC5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1MLC5" } ] }, { "ec_number": "3.1.3.48", "activity": "O-phospho-L-tyrosyl-[protein] + H2O = L-tyrosyl-[protein] + phosphate.", "evidence": [ { "id": "A0A3Q1MLC5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1MLC5" } ] }, { "ec_number": "3.1.3.48", "activity": "", "evidence": [ { "id": "A0A3Q1MLC5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1MLC5" } ] }, { "ec_number": "3.1.3.16", "activity": "", "evidence": [ { "id": "A0A3Q1MLC5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1MLC5" } ] } ] }, { "uniprot_ac": "A0A3Q1MV48", "gene_name": "CDC14A", "activity": [ { "ec_number": "3.1.3.16", "activity": "O-phospho-L-threonyl-[protein] + H2O = L-threonyl-[protein] + phosphate.", "evidence": [ { "id": "A0A3Q1MV48", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1MV48" } ] }, { "ec_number": "3.1.3.48", "activity": "O-phospho-L-tyrosyl-[protein] + H2O = L-tyrosyl-[protein] + phosphate.", "evidence": [ { "id": "A0A3Q1MV48", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1MV48" } ] }, { "ec_number": "3.1.3.16", "activity": "", "evidence": [ { "id": "A0A3Q1MV48", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1MV48" } ] }, { "ec_number": "3.1.3.48", "activity": "", "evidence": [ { "id": "A0A3Q1MV48", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1MV48" } ] } ] }, { "uniprot_ac": "A0A3Q1MZU1", "gene_name": "CTDSPL2", "activity": [ { "ec_number": "3.1.3.16", "activity": "O-phospho-L-threonyl-[protein] + H2O = L-threonyl-[protein] + phosphate.", "evidence": [ { "id": "A0A3Q1MZU1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1MZU1" } ] }, { "ec_number": "3.1.3.16", "activity": "", "evidence": [ { "id": "A0A3Q1MZU1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1MZU1" } ] } ] }, { "uniprot_ac": "A0A3Q1N224", "gene_name": "PHLPP1", "activity": [ { "ec_number": "3.1.3.16", "activity": "O-phospho-L-threonyl-[protein] + H2O = L-threonyl-[protein] + phosphate.", "evidence": [ { "id": "A0A3Q1N224", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1N224" } ] }, { "ec_number": "3.1.3.16", "activity": "", "evidence": [ { "id": "A0A3Q1N224", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1N224" } ] } ] }, { "uniprot_ac": "A0A3Q1N5B2", "gene_name": "CDC14B", "activity": [ { "ec_number": "3.1.3.48", "activity": "O-phospho-L-tyrosyl-[protein] + H2O = L-tyrosyl-[protein] + phosphate.", "evidence": [ { "id": "A0A3Q1N5B2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1N5B2" } ] }, { "ec_number": "3.1.3.48", "activity": "", "evidence": [ { "id": "A0A3Q1N5B2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1N5B2" } ] } ] }, { "uniprot_ac": "A0AAA9RTM1", "gene_name": "DUSP22", "activity": [ { "ec_number": "3.1.3.16", "activity": "O-phospho-L-threonyl-[protein] + H2O = L-threonyl-[protein] + phosphate.", "evidence": [ { "id": "A0AAA9RTM1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9RTM1" } ] }, { "ec_number": "3.1.3.48", "activity": "O-phospho-L-tyrosyl-[protein] + H2O = L-tyrosyl-[protein] + phosphate.", "evidence": [ { "id": "A0AAA9RTM1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9RTM1" } ] }, { "ec_number": "3.1.3.16", "activity": "", "evidence": [ { "id": "A0AAA9RTM1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9RTM1" } ] }, { "ec_number": "3.1.3.48", "activity": "", "evidence": [ { "id": "A0AAA9RTM1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9RTM1" } ] } ] }, { "uniprot_ac": "A0AAA9S454", "gene_name": "LOC112441581", "activity": [ { "ec_number": "3.1.3.16", "activity": "O-phospho-L-threonyl-[protein] + H2O = L-threonyl-[protein] + phosphate.", "evidence": [ { "id": "A0AAA9S454", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9S454" } ] }, { "ec_number": "3.1.3.16", "activity": "", "evidence": [ { "id": "A0AAA9S454", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9S454" } ] } ] }, { "uniprot_ac": "A0AAA9S745", "gene_name": "CTDSPL", "activity": [ { "ec_number": "3.1.3.16", "activity": "O-phospho-L-threonyl-[protein] + H2O = L-threonyl-[protein] + phosphate.", "evidence": [ { "id": "A0AAA9S745", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9S745" } ] }, { "ec_number": "3.1.3.16", "activity": "", "evidence": [ { "id": "A0AAA9S745", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9S745" } ] } ] }, { "uniprot_ac": "A0AAA9SCR0", "gene_name": "LOC112441582", "activity": [ { "ec_number": "3.1.3.16", "activity": "O-phospho-L-threonyl-[protein] + H2O = L-threonyl-[protein] + phosphate.", "evidence": [ { "id": "A0AAA9SCR0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9SCR0" } ] }, { "ec_number": "3.1.3.16", "activity": "", "evidence": [ { "id": "A0AAA9SCR0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9SCR0" } ] } ] }, { "uniprot_ac": "A0AAA9SWY4", "gene_name": "CPPED1", "activity": [ { "ec_number": "3.1.3.16", "activity": "O-phospho-L-threonyl-[protein] + H2O = L-threonyl-[protein] + phosphate.", "evidence": [ { "id": "A0AAA9SWY4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9SWY4" } ] }, { "ec_number": "3.1.3.16", "activity": "", "evidence": [ { "id": "A0AAA9SWY4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9SWY4" } ] } ] }, { "uniprot_ac": "A0AAA9T455", "gene_name": "CDKN3", "activity": [ { "ec_number": "3.1.3.16", "activity": "O-phospho-L-threonyl-[protein] + H2O = L-threonyl-[protein] + phosphate.", "evidence": [ { "id": "A0AAA9T455", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9T455" } ] }, { "ec_number": "3.1.3.48", "activity": "O-phospho-L-tyrosyl-[protein] + H2O = L-tyrosyl-[protein] + phosphate.", "evidence": [ { "id": "A0AAA9T455", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9T455" } ] }, { "ec_number": "3.1.3.16", "activity": "", "evidence": [ { "id": "A0AAA9T455", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9T455" } ] }, { "ec_number": "3.1.3.48", "activity": "", "evidence": [ { "id": "A0AAA9T455", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9T455" } ] } ] }, { "uniprot_ac": "A0AAA9TD32", "gene_name": "CTDP1", "activity": [ { "ec_number": "3.1.3.16", "activity": "O-phospho-L-threonyl-[protein] + H2O = L-threonyl-[protein] + phosphate.", "evidence": [ { "id": "A0AAA9TD32", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TD32" } ] }, { "ec_number": "3.1.3.16", "activity": "", "evidence": [ { "id": "A0AAA9TD32", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TD32" } ] } ] }, { "uniprot_ac": "A0AAA9TT76", "gene_name": "PPP3CC", "activity": [ { "ec_number": "3.1.3.16", "activity": "O-phospho-L-threonyl-[protein] + H2O = L-threonyl-[protein] + phosphate.", "evidence": [ { "id": "A0AAA9TT76", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TT76" } ] }, { "ec_number": "3.1.3.16", "activity": "", "evidence": [ { "id": "A0AAA9TT76", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TT76" } ] } ] }, { "uniprot_ac": "A0AAA9TV14", "gene_name": "CTDSP1", "activity": [ { "ec_number": "3.1.3.16", "activity": "O-phospho-L-threonyl-[protein] + H2O = L-threonyl-[protein] + phosphate.", "evidence": [ { "id": "A0AAA9TV14", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TV14" } ] }, { "ec_number": "3.1.3.16", "activity": "", "evidence": [ { "id": "A0AAA9TV14", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TV14" } ] } ] }, { "uniprot_ac": "A0AAA9U0H6", "gene_name": "PTEN", "activity": [ { "ec_number": "3.1.3.67", "activity": "a 1,2-diacyl-sn-glycero-3-phospho-(1D-myo-inositol-3,4,5-trisphosphate) + H2O = a 1,2-diacyl-sn-glycero-3-phospho-(1D-myo-inositol-4,5-bisphosphate) + phosphate.", "evidence": [ { "id": "A0AAA9U0H6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9U0H6" } ] }, { "ec_number": "3.1.3.16", "activity": "O-phospho-L-threonyl-[protein] + H2O = L-threonyl-[protein] + phosphate.", "evidence": [ { "id": "A0AAA9U0H6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9U0H6" } ] }, { "ec_number": "3.1.3.48", "activity": "O-phospho-L-tyrosyl-[protein] + H2O = L-tyrosyl-[protein] + phosphate.", "evidence": [ { "id": "A0AAA9U0H6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9U0H6" } ] }, { "ec_number": "3.1.3.48", "activity": "", "evidence": [ { "id": "A0AAA9U0H6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9U0H6" } ] }, { "ec_number": "3.1.3.67", "activity": "", "evidence": [ { "id": "A0AAA9U0H6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9U0H6" } ] }, { "ec_number": "3.1.3.16", "activity": "", "evidence": [ { "id": "A0AAA9U0H6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9U0H6" } ] } ] }, { "uniprot_ac": "A0AAF6DLF7", "gene_name": "DUSP7", "activity": [ { "ec_number": "3.1.3.16", "activity": "O-phospho-L-threonyl-[protein] + H2O = L-threonyl-[protein] + phosphate.", "evidence": [ { "id": "A0AAF6DLF7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAF6DLF7" } ] }, { "ec_number": "3.1.3.48", "activity": "O-phospho-L-tyrosyl-[protein] + H2O = L-tyrosyl-[protein] + phosphate.", "evidence": [ { "id": "A0AAF6DLF7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAF6DLF7" } ] }, { "ec_number": "3.1.3.48", "activity": "", "evidence": [ { "id": "A0AAF6DLF7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAF6DLF7" } ] }, { "ec_number": "3.1.3.16", "activity": "", "evidence": [ { "id": "A0AAF6DLF7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAF6DLF7" } ] } ] }, { "uniprot_ac": "A0AAF6YJP2", "gene_name": "SSU72", "activity": [ { "ec_number": "3.1.3.16", "activity": "O-phospho-L-threonyl-[protein] + H2O = L-threonyl-[protein] + phosphate.", "evidence": [ { "id": "A0AAF6YJP2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAF6YJP2" } ] }, { "ec_number": "3.1.3.16", "activity": "", "evidence": [ { "id": "A0AAF6YJP2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAF6YJP2" } ] } ] }, { "uniprot_ac": "A0ABI0P1A3", "gene_name": "SSH2", "activity": [ { "ec_number": "3.1.3.16", "activity": "O-phospho-L-threonyl-[protein] + H2O = L-threonyl-[protein] + phosphate.", "evidence": [ { "id": "A0ABI0P1A3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0ABI0P1A3" } ] }, { "ec_number": "3.1.3.16", "activity": "", "evidence": [ { "id": "A0ABI0P1A3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0ABI0P1A3" } ] } ] }, { "uniprot_ac": "A5PJW8", "gene_name": "POLR2B", "activity": [ { "ec_number": "3.1.13.-", "activity": "", "evidence": [ { "id": "A5PJW8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A5PJW8" } ] }, { "ec_number": "2.7.7.48", "activity": "RNA(n) + a ribonucleoside 5'-triphosphate = RNA(n+1) + diphosphate.", "evidence": [ { "id": "A5PJW8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A5PJW8" } ] }, { "ec_number": "2.7.7.6", "activity": "RNA(n) + a ribonucleoside 5'-triphosphate = RNA(n+1) + diphosphate.", "evidence": [ { "id": "A5PJW8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A5PJW8" } ] }, { "ec_number": "2.7.7.6", "activity": "", "evidence": [ { "id": "A5PJW8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A5PJW8" } ] } ] }, { "uniprot_ac": "A5PJZ2", "gene_name": "PPM1L", "activity": [ { "ec_number": "3.1.3.16", "activity": "O-phospho-L-threonyl-[protein] + H2O = L-threonyl-[protein] + phosphate.", "evidence": [ { "id": "A5PJZ2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A5PJZ2" } ] }, { "ec_number": "3.1.3.16", "activity": "", "evidence": [ { "id": "A5PJZ2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A5PJZ2" } ] } ] }, { "uniprot_ac": "A6H772", "gene_name": "PPP4C", "activity": [ { "ec_number": "3.1.3.16", "activity": "O-phospho-L-threonyl-[protein] + H2O = L-threonyl-[protein] + phosphate.", "evidence": [ { "id": "A6H772", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A6H772" } ] }, { "ec_number": "3.1.3.16", "activity": "", "evidence": [ { "id": "A6H772", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A6H772" } ] } ] }, { "uniprot_ac": "E1B9Y5", "gene_name": "PPEF2", "activity": [ { "ec_number": "3.1.3.16", "activity": "O-phospho-L-threonyl-[protein] + H2O = L-threonyl-[protein] + phosphate.", "evidence": [ { "id": "E1B9Y5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1B9Y5" } ] }, { "ec_number": "3.1.3.16", "activity": "", "evidence": [ { "id": "E1B9Y5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1B9Y5" } ] } ] }, { "uniprot_ac": "E1BAB2", "gene_name": "", "activity": [ { "ec_number": "3.1.3.16", "activity": "O-phospho-L-threonyl-[protein] + H2O = L-threonyl-[protein] + phosphate.", "evidence": [ { "id": "E1BAB2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BAB2" } ] }, { "ec_number": "3.1.3.16", "activity": "", "evidence": [ { "id": "E1BAB2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BAB2" } ] } ] }, { "uniprot_ac": "E1BBD9", "gene_name": "LOC112445820", "activity": [ { "ec_number": "3.1.3.16", "activity": "O-phospho-L-threonyl-[protein] + H2O = L-threonyl-[protein] + phosphate.", "evidence": [ { "id": "E1BBD9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BBD9" } ] }, { "ec_number": "3.1.3.16", "activity": "", "evidence": [ { "id": "E1BBD9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BBD9" } ] } ] }, { "uniprot_ac": "E1BEW5", "gene_name": "PPTC7", "activity": [ { "ec_number": "3.1.3.16", "activity": "O-phospho-L-threonyl-[protein] + H2O = L-threonyl-[protein] + phosphate.", "evidence": [ { "id": "E1BEW5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BEW5" } ] }, { "ec_number": "3.1.3.16", "activity": "", "evidence": [ { "id": "E1BEW5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BEW5" } ] } ] }, { "uniprot_ac": "E1BF95", "gene_name": "PPM1F", "activity": [ { "ec_number": "3.1.3.16", "activity": "O-phospho-L-threonyl-[protein] + H2O = L-threonyl-[protein] + phosphate.", "evidence": [ { "id": "E1BF95", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BF95" } ] }, { "ec_number": "3.1.3.16", "activity": "", "evidence": [ { "id": "E1BF95", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BF95" } ] } ] }, { "uniprot_ac": "E1BIE7", "gene_name": "PGAM5", "activity": [ { "ec_number": "3.1.3.16", "activity": "O-phospho-L-threonyl-[protein] + H2O = L-threonyl-[protein] + phosphate.", "evidence": [ { "id": "E1BIE7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BIE7" } ] }, { "ec_number": "3.1.3.16", "activity": "", "evidence": [ { "id": "E1BIE7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BIE7" } ] } ] }, { "uniprot_ac": "E1BIZ2", "gene_name": "SSH1", "activity": [ { "ec_number": "3.1.3.16", "activity": "O-phospho-L-threonyl-[protein] + H2O = L-threonyl-[protein] + phosphate.", "evidence": [ { "id": "E1BIZ2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BIZ2" } ] }, { "ec_number": "3.1.3.16", "activity": "", "evidence": [ { "id": "E1BIZ2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BIZ2" } ] } ] }, { "uniprot_ac": "E1BMD4", "gene_name": "PHLPP2", "activity": [ { "ec_number": "3.1.3.16", "activity": "O-phospho-L-threonyl-[protein] + H2O = L-threonyl-[protein] + phosphate.", "evidence": [ { "id": "E1BMD4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BMD4" } ] }, { "ec_number": "3.1.3.16", "activity": "", "evidence": [ { "id": "E1BMD4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BMD4" } ] } ] }, { "uniprot_ac": "F1MBQ1", "gene_name": "PPEF1", "activity": [ { "ec_number": "3.1.3.16", "activity": "O-phospho-L-threonyl-[protein] + H2O = L-threonyl-[protein] + phosphate.", "evidence": [ { "id": "F1MBQ1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MBQ1" } ] }, { "ec_number": "3.1.3.16", "activity": "", "evidence": [ { "id": "F1MBQ1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MBQ1" } ] } ] }, { "uniprot_ac": "F1ME76", "gene_name": "DUSP13B", "activity": [ { "ec_number": "3.1.3.16", "activity": "O-phospho-L-threonyl-[protein] + H2O = L-threonyl-[protein] + phosphate.", "evidence": [ { "id": "F1ME76", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1ME76" } ] }, { "ec_number": "3.1.3.48", "activity": "O-phospho-L-tyrosyl-[protein] + H2O = L-tyrosyl-[protein] + phosphate.", "evidence": [ { "id": "F1ME76", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1ME76" } ] }, { "ec_number": "3.1.3.16", "activity": "", "evidence": [ { "id": "F1ME76", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1ME76" } ] }, { "ec_number": "3.1.3.48", "activity": "", "evidence": [ { "id": "F1ME76", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1ME76" } ] } ] }, { "uniprot_ac": "F1MEZ2", "gene_name": "DUSP9", "activity": [ { "ec_number": "3.1.3.16", "activity": "O-phospho-L-threonyl-[protein] + H2O = L-threonyl-[protein] + phosphate.", "evidence": [ { "id": "F1MEZ2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MEZ2" } ] }, { "ec_number": "3.1.3.48", "activity": "O-phospho-L-tyrosyl-[protein] + H2O = L-tyrosyl-[protein] + phosphate.", "evidence": [ { "id": "F1MEZ2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MEZ2" } ] }, { "ec_number": "3.1.3.48", "activity": "", "evidence": [ { "id": "F1MEZ2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MEZ2" } ] }, { "ec_number": "3.1.3.16", "activity": "", "evidence": [ { "id": "F1MEZ2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MEZ2" } ] } ] }, { "uniprot_ac": "F1MI92", "gene_name": "SSH3", "activity": [ { "ec_number": "3.1.3.16", "activity": "O-phospho-L-threonyl-[protein] + H2O = L-threonyl-[protein] + phosphate.", "evidence": [ { "id": "F1MI92", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MI92" } ] }, { "ec_number": "3.1.3.16", "activity": "", "evidence": [ { "id": "F1MI92", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MI92" } ] } ] }, { "uniprot_ac": "F1MI99", "gene_name": "DUSP1", "activity": [ { "ec_number": "3.1.3.16", "activity": "O-phospho-L-threonyl-[protein] + H2O = L-threonyl-[protein] + phosphate.", "evidence": [ { "id": "F1MI99", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MI99" } ] }, { "ec_number": "3.1.3.48", "activity": "O-phospho-L-tyrosyl-[protein] + H2O = L-tyrosyl-[protein] + phosphate.", "evidence": [ { "id": "F1MI99", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MI99" } ] }, { "ec_number": "3.1.3.48", "activity": "", "evidence": [ { "id": "F1MI99", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MI99" } ] }, { "ec_number": "3.1.3.16", "activity": "", "evidence": [ { "id": "F1MI99", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MI99" } ] } ] }, { "uniprot_ac": "F1MM08", "gene_name": "DUSP4", "activity": [ { "ec_number": "3.1.3.16", "activity": "O-phospho-L-threonyl-[protein] + H2O = L-threonyl-[protein] + phosphate.", "evidence": [ { "id": "F1MM08", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MM08" } ] }, { "ec_number": "3.1.3.48", "activity": "O-phospho-L-tyrosyl-[protein] + H2O = L-tyrosyl-[protein] + phosphate.", "evidence": [ { "id": "F1MM08", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MM08" } ] }, { "ec_number": "3.1.3.48", "activity": "", "evidence": [ { "id": "F1MM08", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MM08" } ] }, { "ec_number": "3.1.3.16", "activity": "", "evidence": [ { "id": "F1MM08", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MM08" } ] } ] }, { "uniprot_ac": "F1MP34", "gene_name": "DUSP2", "activity": [ { "ec_number": "3.1.3.16", "activity": "O-phospho-L-threonyl-[protein] + H2O = L-threonyl-[protein] + phosphate.", "evidence": [ { "id": "F1MP34", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MP34" } ] }, { "ec_number": "3.1.3.48", "activity": "O-phospho-L-tyrosyl-[protein] + H2O = L-tyrosyl-[protein] + phosphate.", "evidence": [ { "id": "F1MP34", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MP34" } ] }, { "ec_number": "3.1.3.48", "activity": "", "evidence": [ { "id": "F1MP34", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MP34" } ] }, { "ec_number": "3.1.3.16", "activity": "", "evidence": [ { "id": "F1MP34", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MP34" } ] } ] }, { "uniprot_ac": "F1MQM7", "gene_name": "DUSP5", "activity": [ { "ec_number": "3.1.3.16", "activity": "O-phospho-L-threonyl-[protein] + H2O = L-threonyl-[protein] + phosphate.", "evidence": [ { "id": "F1MQM7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MQM7" } ] }, { "ec_number": "3.1.3.48", "activity": "O-phospho-L-tyrosyl-[protein] + H2O = L-tyrosyl-[protein] + phosphate.", "evidence": [ { "id": "F1MQM7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MQM7" } ] }, { "ec_number": "3.1.3.16", "activity": "", "evidence": [ { "id": "F1MQM7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MQM7" } ] }, { "ec_number": "3.1.3.48", "activity": "", "evidence": [ { "id": "F1MQM7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MQM7" } ] } ] }, { "uniprot_ac": "F1MW60", "gene_name": "PDXP", "activity": [ { "ec_number": "3.1.3.74", "activity": "pyridoxal 5'-phosphate + H2O = pyridoxal + phosphate.", "evidence": [ { "id": "F1MW60", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MW60" } ] }, { "ec_number": "3.1.3.16", "activity": "O-phospho-L-threonyl-[protein] + H2O = L-threonyl-[protein] + phosphate.", "evidence": [ { "id": "F1MW60", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MW60" } ] }, { "ec_number": "3.1.3.16", "activity": "", "evidence": [ { "id": "F1MW60", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MW60" } ] }, { "ec_number": "3.1.3.74", "activity": "", "evidence": [ { "id": "F1MW60", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MW60" } ] } ] }, { "uniprot_ac": "F1MW70", "gene_name": "DUSP12", "activity": [ { "ec_number": "3.1.3.16", "activity": "O-phospho-L-threonyl-[protein] + H2O = L-threonyl-[protein] + phosphate.", "evidence": [ { "id": "F1MW70", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MW70" } ] }, { "ec_number": "3.1.3.48", "activity": "O-phospho-L-tyrosyl-[protein] + H2O = L-tyrosyl-[protein] + phosphate.", "evidence": [ { "id": "F1MW70", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MW70" } ] }, { "ec_number": "3.1.3.48", "activity": "", "evidence": [ { "id": "F1MW70", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MW70" } ] }, { "ec_number": "3.1.3.16", "activity": "", "evidence": [ { "id": "F1MW70", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MW70" } ] } ] }, { "uniprot_ac": "F1N580", "gene_name": "PPM1E", "activity": [ { "ec_number": "3.1.3.16", "activity": "O-phospho-L-threonyl-[protein] + H2O = L-threonyl-[protein] + phosphate.", "evidence": [ { "id": "F1N580", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1N580" } ] }, { "ec_number": "3.1.3.16", "activity": "", "evidence": [ { "id": "F1N580", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1N580" } ] } ] }, { "uniprot_ac": "F1N719", "gene_name": "PPP5C", "activity": [ { "ec_number": "3.1.3.16", "activity": "O-phospho-L-threonyl-[protein] + H2O = L-threonyl-[protein] + phosphate.", "evidence": [ { "id": "F1N719", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1N719" } ] }, { "ec_number": "3.1.3.16", "activity": "", "evidence": [ { "id": "F1N719", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1N719" } ] } ] }, { "uniprot_ac": "F2Z4J6", "gene_name": "GTF2B", "activity": [ { "ec_number": "2.3.1.48", "activity": "L-lysyl-[histone] + acetyl-CoA = N(6)-acetyl-L-lysyl-[histone] + CoA + H(+).", "evidence": [ { "id": "F2Z4J6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F2Z4J6" } ] }, { "ec_number": "2.3.1.48", "activity": "", "evidence": [ { "id": "F2Z4J6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F2Z4J6" } ] } ] }, { "uniprot_ac": "F6RRD7", "gene_name": "RPAP2", "activity": [ { "ec_number": "3.1.3.16", "activity": "O-phospho-L-threonyl-[protein] + H2O = L-threonyl-[protein] + phosphate.", "evidence": [ { "id": "F6RRD7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F6RRD7" } ] }, { "ec_number": "3.1.3.16", "activity": "", "evidence": [ { "id": "F6RRD7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F6RRD7" } ] } ] }, { "uniprot_ac": "G3MZY8", "gene_name": "POLR2A", "activity": [ { "ec_number": "3.1.13.-", "activity": "", "evidence": [ { "id": "G3MZY8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3MZY8" } ] }, { "ec_number": "2.7.7.48", "activity": "RNA(n) + a ribonucleoside 5'-triphosphate = RNA(n+1) + diphosphate.", "evidence": [ { "id": "G3MZY8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3MZY8" } ] }, { "ec_number": "2.7.7.6", "activity": "RNA(n) + a ribonucleoside 5'-triphosphate = RNA(n+1) + diphosphate.", "evidence": [ { "id": "G3MZY8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3MZY8" } ] }, { "ec_number": "2.7.7.6", "activity": "", "evidence": [ { "id": "G3MZY8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3MZY8" } ] } ] }, { "uniprot_ac": "G3N3B3", "gene_name": "PPM1N", "activity": [ { "ec_number": "3.1.3.16", "activity": "O-phospho-L-threonyl-[protein] + H2O = L-threonyl-[protein] + phosphate.", "evidence": [ { "id": "G3N3B3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3N3B3" } ] }, { "ec_number": "3.1.3.16", "activity": "", "evidence": [ { "id": "G3N3B3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3N3B3" } ] } ] }, { "uniprot_ac": "O62829", "gene_name": "PPM1A", "activity": [ { "ec_number": "3.1.3.16", "activity": "O-phospho-L-threonyl-[protein] + H2O = L-threonyl-[protein] + phosphate.", "evidence": [ { "id": "O62829", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/O62829" } ] }, { "ec_number": "3.1.3.16", "activity": "", "evidence": [ { "id": "O62829", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/O62829" } ] } ] }, { "uniprot_ac": "O62830", "gene_name": "PPM1B", "activity": [ { "ec_number": "3.1.3.16", "activity": "O-phospho-L-threonyl-[protein] + H2O = L-threonyl-[protein] + phosphate.", "evidence": [ { "id": "O62830", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/O62830" } ] }, { "ec_number": "3.1.3.16", "activity": "", "evidence": [ { "id": "O62830", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/O62830" } ] } ] }, { "uniprot_ac": "P0C591", "gene_name": "DUSP29", "activity": [ { "ec_number": "3.1.3.16", "activity": "O-phospho-L-threonyl-[protein] + H2O = L-threonyl-[protein] + phosphate.", "evidence": [ { "id": "P0C591", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P0C591" } ] }, { "ec_number": "3.1.3.48", "activity": "O-phospho-L-tyrosyl-[protein] + H2O = L-tyrosyl-[protein] + phosphate.", "evidence": [ { "id": "P0C591", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P0C591" } ] } ] }, { "uniprot_ac": "P48452", "gene_name": "PPP3CA", "activity": [ { "ec_number": "3.1.3.16", "activity": "O-phospho-L-threonyl-[protein] + H2O = L-threonyl-[protein] + phosphate.", "evidence": [ { "id": "P48452", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P48452" } ] }, { "ec_number": "3.1.3.16", "activity": "", "evidence": [ { "id": "P48452", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P48452" } ] } ] }, { "uniprot_ac": "P61287", "gene_name": "PPP1CC", "activity": [ { "ec_number": "3.1.3.16", "activity": "O-phospho-L-threonyl-[protein] + H2O = L-threonyl-[protein] + phosphate.", "evidence": [ { "id": "P61287", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P61287" } ] }, { "ec_number": "3.1.3.16", "activity": "", "evidence": [ { "id": "P61287", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P61287" } ] } ] }, { "uniprot_ac": "P67774", "gene_name": "PPP2CA", "activity": [ { "ec_number": "3.1.3.16", "activity": "O-phospho-L-threonyl-[protein] + H2O = L-threonyl-[protein] + phosphate.", "evidence": [ { "id": "P67774", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P67774" } ] }, { "ec_number": "3.1.3.16", "activity": "", "evidence": [ { "id": "P67774", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P67774" } ] } ] }, { "uniprot_ac": "P79126", "gene_name": "PPM1G", "activity": [ { "ec_number": "3.1.3.16", "activity": "O-phospho-L-threonyl-[protein] + H2O = L-threonyl-[protein] + phosphate.", "evidence": [ { "id": "P79126", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P79126" } ] }, { "ec_number": "3.1.3.16", "activity": "", "evidence": [ { "id": "P79126", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P79126" } ] } ] }, { "uniprot_ac": "Q0IID7", "gene_name": "DUSP10", "activity": [ { "ec_number": "3.1.3.16", "activity": "O-phospho-L-threonyl-[protein] + H2O = L-threonyl-[protein] + phosphate.", "evidence": [ { "id": "Q0IID7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q0IID7" } ] }, { "ec_number": "3.1.3.48", "activity": "O-phospho-L-tyrosyl-[protein] + H2O = L-tyrosyl-[protein] + phosphate.", "evidence": [ { "id": "Q0IID7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q0IID7" } ] }, { "ec_number": "3.1.3.16", "activity": "", "evidence": [ { "id": "Q0IID7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q0IID7" } ] }, { "ec_number": "3.1.3.48", "activity": "", "evidence": [ { "id": "Q0IID7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q0IID7" } ] } ] }, { 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[], "phosphorylation_sites": [ 9, 216, 432, 479 ], "sequon_annotation_sites": [ { "start_pos": 234, "end_pos": 236 }, { "start_pos": 300, "end_pos": 302 }, { "start_pos": 69, "end_pos": 71 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 4 }, { "field": "total_sites", "count": 4 } ], "sort_fields": [ "start_pos", "end_pos", "kinase_uniprot_canonical_ac", "kinase_gene_name", "residue", "comment", "site_lbl" ] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ], "tool_support": { "graph_view": "yes" } }, { "uniprot_canonical_ac": "P46626-1", "uniprot_ac": "P46626", "uniprot_id": "ADRB3_BOVIN", "mass": { "chemical_mass": 42903.0, "monoisotopic_mass": 42903.0 }, "refseq": { "ac": "NP_776657", "name": "beta-3 adrenergic receptor", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_776657" }, "gene_names": [ { "name": "ADRB3", "type": "recommended", "evidence": [ { "id": "P46626", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P46626" } ] }, { "name": "ADRB3", "type": "synonym", "evidence": [ { "id": "NP_776657", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_776657" } ] } ], "protein_names": [ { "name": "Beta-3 adrenergic receptor", "type": "recommended", "evidence": [ { "id": "P46626", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P46626/entry#names_and_taxonomy" } ] }, { "name": "Beta-3 adrenoceptor", "type": "synonym", "evidence": [ { "id": "P46626", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P46626/entry#names_and_taxonomy" } ] }, { "name": "Beta-3 adrenoreceptor", "type": "synonym", "evidence": [ { "id": "P46626", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P46626/entry#names_and_taxonomy" } ] }, { "name": "adrenergic, beta 3, receptor", "type": "synonym", "evidence": [ { "id": "NP_776657", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_776657" } ] }, { "name": "adrenergic, beta-3-, receptor", "type": "synonym", "evidence": [ { "id": "NP_776657", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_776657" } ] }, { "name": "beta-3 adrenergic receptor", "type": "synonym", "evidence": [ { "id": "NP_776657", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_776657" } ] }, { "name": "beta-3 adrenoceptor", "type": "synonym", "evidence": [ { "id": "NP_776657", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_776657" } ] }, { "name": "beta-3 adrenoreceptor", "type": "synonym", "evidence": [ { "id": "NP_776657", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_776657" } ] } ], "function": [ { "annotation": "Beta 1,2 and 3-adrenergic receptors in cattle were positively associated with hepatic activities of gluconeogenetic enzymes and with plasma glucose levels, suggesting functional importance", "evidence": [ { "database": "RefSeq", "id": "NP_776657", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_776657" }, { "database": "PubMed", "id": "15760672", "url": "https://glygen.org/publication/PubMed/15760672" } ] }, { "annotation": "G protein-coupled receptor for catecholamines that couples to both G(s) and G(i) proteins, leading to either activation or inhibition of adenylate cyclase and cAMP-dependent pathway, respectively. The rank order of potency for physiological agonists is norepinephrine > epinephrine (By similarity). Involved in the regulation of thermogenesis and lipolysis in brown and white adipose tissue, after coupling to G(s) proteins and stimulation of the cAMP-PKA axis (By similarity). Also activates lipolytic process by coupling to G(i) proteins and consequent initiation of the ERK1/2 MAP kinase cascade. Participates in relaxation of the blood vessels and the urinary bladder. Also mediates negative inotropic effects in cardiomyocytes through activation of an NO synthase pathway and subsequent increase in cGMP levels, possibly involving G(i/o) protein-mediated coupling (By similarity).", "evidence": [ { "database": "UniProtKB", "id": "P46626", "url": "https://www.uniprot.org/uniprotkb/P46626#function" }, { "database": "UniProtKB", "id": "P13945", "url": "https://www.uniprot.org/uniprotkb/P13945#function" }, { "database": "UniProtKB", "id": "P25962", "url": "https://www.uniprot.org/uniprotkb/P25962#function" }, { "database": "UniProtKB", "id": "A0A452DJP2", "url": "https://www.uniprot.org/uniprotkb/A0A452DJP2#function" }, { "database": "UniProtKB", "id": "ARBA00094414", "url": "https://www.uniprot.org/uniprotkb/ARBA00094414#function" }, { "database": "UniProtKB", "id": "A0A3Q1MQZ8", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1MQZ8#function" } ] }, { "annotation": "Of the beta-adrenergic receptors, adrenergic beta(2)-receptor type was most highly expressed in the mammary gland of dairy cows followed by beta(1) and beta(3)", "evidence": [ { "database": "RefSeq", "id": "NP_776657", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_776657" }, { "database": "PubMed", "id": "12586313", "url": "https://glygen.org/publication/PubMed/12586313" } ] }, { "annotation": "Small G protein Rac1 is a key regulator of beta(3)AR signaling in cultured aortic endothelial cells with potentially important implications for the pathways involved in adrenergic modulation of eNOS pathways in the vascular wall", "evidence": [ { "database": "RefSeq", "id": "NP_776657", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_776657" }, { "database": "PubMed", "id": "17855349", "url": "https://glygen.org/publication/PubMed/17855349" } ] }, { "annotation": "Variation in the promoter region of bovine ADRB3 was investigated.", "evidence": [ { "database": "RefSeq", "id": "NP_776657", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_776657" }, { "database": "PubMed", "id": "20091127", "url": "https://glygen.org/publication/PubMed/20091127" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Bos taurus", "taxid": 9913, "evidence": [ { "database": "UniProtKB", "id": "P46626", "url": "https://www.uniprot.org/uniprotkb/P46626" } ], "common_name": "Bovine", "glygen_name": "Bovine", "reference_species": "Bos taurus [9913]" } ], "gene": [ { "name": "ADRB3", "url": "https://www.uniprot.org/uniprotkb/P46626", "locus": { "chromosome": "27", "start_pos": 33208460, "end_pos": 33211313, "strand": "+", "evidence": [ { "database": "Ensembl Gene", "id": "ENSBTAG00000017981", "url": "https://www.ensembl.org/id/ENSBTAG00000017981" } ] } } ], "crossref": [ { "id": "P46626", "url": "https://alphafold.ebi.ac.uk/entry/P46626", "database": "AlphaFoldDB", "categories": [] }, { "id": "ENSBTAG00000017981", "url": "https://bgee.org/?page=gene&gene_id=ENSBTAG00000017981", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "281606", "url": "https://www.ncbi.nlm.nih.gov/gene/281606", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR000276", "url": "https://www.ebi.ac.uk/interpro/entry/IPR000276", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR000681", "url": "https://www.ebi.ac.uk/interpro/entry/IPR000681", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR002233", "url": "https://www.ebi.ac.uk/interpro/entry/IPR002233", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR017452", "url": "https://www.ebi.ac.uk/interpro/entry/IPR017452", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "bta:281606", "url": "https://www.genome.jp/dbget-bin/www_bget?bta:281606", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "CAFASNI", "url": "https://omabrowser.org/oma/group/CAFASNI/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "A0A3Q1MQZ8", "url": "https://www.orthodb.org/?gene=A0A3Q1MQZ8", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A452DJP2", "url": "https://www.orthodb.org/?gene=A0A452DJP2", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "P46626", "url": "https://www.orthodb.org/?gene=P46626", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR24248", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR24248", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR24248:SF3", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR24248:SF3", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00001", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00001", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "R-BTA-390696", "url": "https://www.reactome.org/PathwayBrowser/#R-BTA-390696", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "R-BTA-418555", "url": "https://www.reactome.org/PathwayBrowser/#R-BTA-418555", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "NP_776657", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_776657", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A3Q1MQZ8", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1MQZ8", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A3Q1MQZ8-1", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1MQZ8-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A452DJP2", "url": "https://www.uniprot.org/uniprotkb/A0A452DJP2", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A452DJP2-1", "url": "https://www.uniprot.org/uniprotkb/A0A452DJP2-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "P46626", "url": "https://www.uniprot.org/uniprotkb/P46626", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "P46626-1", "url": "https://www.uniprot.org/uniprotkb/P46626-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MAPWPPGNSSLTPWPDIPTLAPNTANASGLPGVPWAVALAGALLALAVLATVGGNLLVIVAIARTPRLQTMTNVFVTSLATADLVVGLLVVPPGATLALTGHWPLGVTGCELWTSVDVLCVTASIETLCALAVDRYLAVTNPLRYGALVTKRRALAAVVLVWVVSAAVSFAPIMSKWWRIGADAEAQRCHSNPRCCTFASNMPYALLSSSVSFYLPLLVMLFVYARVFVVATRQLRLLRRELGRFPPEESPPAPSRSGSPGLAGPCASPAGVPSYGRRPARLLPLREHRALRTLGLIMGTFTLCWLPFFVVNVVRALGGPSLVSGPTFLALNWLGYANSAFNPLIYCRSPDFRSAFRRLLCRCRPEEHLAAASPPRAPSGAPTALTSPAGPMQPPELDGASCGLS", "length": 405, "header": "sp|P46626-1|ADRB3_BOVIN Isoform 1 of Beta-3 adrenergic receptor OS=Bos taurus OX=9913 GN=ADRB3 PE=2 SV=1 CANONICAL=P46626-1" }, "isoforms": [ { "isoform_ac": "A0A3Q1MQZ8-1", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1MQZ8/entry", "sequence": { "sequence": "MPPPLSRVSWETLSLIPSRPTRDAGMAPWPPGNSSLTPWPDIPTLAPNTANASGLPGVPWAVALAGALLALAVLATVGGNLLVIVAIARTPRLQTMTNVFVTSLATADLVVGLLVVPPGATLALTGHWPLGVTGCELWTSVDVLCVTASIETLCALAVDRYLAVTNPLRYGALVTKRRALAAVVLVWVVSAAVSFAPIMSKWWRIGADAEAQRCHSNPRCCTFASNMPYALLSSSVSFYLPLLVMLFVYARVFVVATRQLRLLRRELGRFPPEESPPAPSRSGSPGLAGPCASPAGVPSYGRRPARLLPLREHRALRTLGLIMGTFTLCWLPFFVVNVVRALGGPSLVSGPTFLALNWLGYANSAFNPLIYCRSPDFRSAFRRLLCRCRPEEHLAAASPPRAPSGAPTALTSPAGPMQPPELDGLIALKVRIRFRNEG", "length": 438, "header": "tr|A0A3Q1MQZ8-1|A0A3Q1MQZ8_BOVIN Computationally mapped isoform of Beta-3 adrenergic receptor OS=Bos taurus OX=9913 GN=ADRB3 PE=3 SV=1 CANONICAL=P46626-1" }, "locus": { "chromosome": "27", "start_pos": 33211114, "end_pos": 33209317, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000085511.2", "url": "https://www.ensembl.org/id/ENSBTAT00000085511.2" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000074082.1", "url": "https://www.ensembl.org/id/ENSBTAP00000074082.1" } ] } }, { "isoform_ac": "A0A452DJP2-1", "url": "https://www.uniprot.org/uniprotkb/A0A452DJP2/entry", "sequence": { "sequence": "MPPPLSRVSWETLSLIPSRPTRDAGMAPWPPGNSSLTPWPDIPTLAPNTANASGLPGVPWAVALAGALLALAVLATVGGNLLVIVAIARTPRLQTMTNVFVTSLATADLVVGLLVVPPGATLALTGHWPLGVTGCELWTSVDVLCVTASIETLCALAVDRYLAVTNPLRYGALVTKRRALAAVVLVWVVSAAVSFAPIMSKWWRIGADAEAQRCHSNPRCCTFASNMPYALLSSSVSFYLPLLVMLFVYARVFVVATRQLRLLRRELGRFPPEESPPAPSRSGSPGLAGPCASPAGVPSYGRRPARLLPLREHRALRTLGLIMGTFTLCWLPFFVVNVVRALGGPSLVSGPTFLALNWLGYANSAFNPLIYCRSPDFRSAFRRLLCRCRPEEHLAAASPPRAPSGAPTALTSPAGPMQPPELDGASCGLS", "length": 430, "header": "tr|A0A452DJP2-1|ADRB3_BOVIN Computationally mapped isoform of Beta-3 adrenergic receptor OS=Bos taurus OX=9913 GN=ADRB3 PE=2 SV=1 CANONICAL=P46626-1" }, "locus": { "chromosome": "27", "start_pos": 33211114, "end_pos": 33209098, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000023923.5", "url": "https://www.ensembl.org/id/ENSBTAT00000023923.5" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000023923.4", "url": "https://www.ensembl.org/id/ENSBTAP00000023923.4" } ] } }, { "isoform_ac": "P46626-1", "url": "https://www.uniprot.org/uniprotkb/P46626/entry#P46626-1", "sequence": { "sequence": "MAPWPPGNSSLTPWPDIPTLAPNTANASGLPGVPWAVALAGALLALAVLATVGGNLLVIVAIARTPRLQTMTNVFVTSLATADLVVGLLVVPPGATLALTGHWPLGVTGCELWTSVDVLCVTASIETLCALAVDRYLAVTNPLRYGALVTKRRALAAVVLVWVVSAAVSFAPIMSKWWRIGADAEAQRCHSNPRCCTFASNMPYALLSSSVSFYLPLLVMLFVYARVFVVATRQLRLLRRELGRFPPEESPPAPSRSGSPGLAGPCASPAGVPSYGRRPARLLPLREHRALRTLGLIMGTFTLCWLPFFVVNVVRALGGPSLVSGPTFLALNWLGYANSAFNPLIYCRSPDFRSAFRRLLCRCRPEEHLAAASPPRAPSGAPTALTSPAGPMQPPELDGASCGLS", "length": 405, "header": "sp|P46626-1|ADRB3_BOVIN Isoform 1 of Beta-3 adrenergic receptor OS=Bos taurus OX=9913 GN=ADRB3 PE=2 SV=1 CANONICAL=P46626-1" }, "locus": {} } ], "glycosylation": [ { "glytoucan_ac": "", "type": "N-linked", "subtype": "other", "prediction_tool_list": [], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "N", "relation": "attached", "comment": "N-linked (GlcNAc...) asparagine", "icn3d_view": {}, "start_pos": 26, "start_aa": "Asn", "end_pos": 26, "end_aa": "Asn", "residue": "Asn", "site_lbl": "Asn26", "evidence": [ { "id": "P46626", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P46626#ptm_processing" } ], "filter_code": "001000000000000000000.00010000000000.0.01000" }, { "glytoucan_ac": "", "type": "N-linked", "subtype": "other", "prediction_tool_list": [], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "N", "relation": "attached", "comment": "N-linked (GlcNAc...) asparagine", "icn3d_view": {}, "start_pos": 8, "start_aa": "Asn", "end_pos": 8, "end_aa": "Asn", "residue": "Asn", "site_lbl": "Asn8", "evidence": [ { "id": "P46626", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P46626#ptm_processing" } ], "filter_code": "001000000000000000000.00010000000000.0.01000" } ], "phosphorylation": [], "glycation": [], "keywords": [ "glycoprotein", "glycoprotein_predicted" ], "publication": [ { "title": "Rapid communication: nucleotide sequences of the bovine, caprine, and ovine beta3-adrenergic receptor genes.", "journal": "J. Anim. 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] }, { "name": "vacuolar H+-ATPase", "type": "synonym", "evidence": [ { "id": "NP_788827", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_788827" } ] }, { "name": "vacuolar proton pump subunit B 1", "type": "synonym", "evidence": [ { "id": "NP_788827", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_788827" } ] } ], "function": [ { "annotation": "Non-catalytic subunit of the V1 complex of vacuolar(H+)-ATPase (V-ATPase), a multisubunit enzyme composed of a peripheral complex (V1) that hydrolyzes ATP and a membrane integral complex (V0) that translocates protons. 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"https://www.uniprot.org/uniprotkb/P31408#function" }, { "database": "UniProtKB", "id": "P15313", "url": "https://www.uniprot.org/uniprotkb/P15313#function" }, { "database": "UniProtKB", "id": "Q91YH6", "url": "https://www.uniprot.org/uniprotkb/Q91YH6#function" }, { "database": "UniProtKB", "id": "A0A3Q1LT17", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1LT17#function" } ] }, { "annotation": "VH(+)-ATPase has been detected in the cell membrane and in intracellular pools in bovine rumen epithelium.", "evidence": [ { "database": "RefSeq", "id": "NP_788827", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_788827" }, { "database": "PubMed", "id": "17989983", "url": "https://glygen.org/publication/PubMed/17989983" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Bos taurus", "taxid": 9913, "evidence": [ { "database": "UniProtKB", "id": "P31407", "url": "https://www.uniprot.org/uniprotkb/P31407" } ], "common_name": "Bovine", "glygen_name": "Bovine", "reference_species": "Bos taurus [9913]" } ], "gene": [ { "name": "ATP6V1B1", "url": "https://www.uniprot.org/uniprotkb/P31407", "locus": { "chromosome": "11", "start_pos": 13454348, "end_pos": 13482388, "strand": "+", "evidence": [ { "database": "Ensembl Gene", "id": "ENSBTAG00000010620", "url": "https://www.ensembl.org/id/ENSBTAG00000010620" } ] } } ], "crossref": [ { "id": "P31407", "url": "https://alphafold.ebi.ac.uk/entry/P31407", "database": "AlphaFoldDB", "categories": [] }, { "id": "ENSBTAG00000010620", "url": "https://bgee.org/?page=gene&gene_id=ENSBTAG00000010620", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "cd01135", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd01135", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "cd18112", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd18112", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "cd18118", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd18118", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "338059", "url": "https://www.ncbi.nlm.nih.gov/gene/338059", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR000194", "url": "https://www.ebi.ac.uk/interpro/entry/IPR000194", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR004100", "url": "https://www.ebi.ac.uk/interpro/entry/IPR004100", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR005723", "url": "https://www.ebi.ac.uk/interpro/entry/IPR005723", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR020003", "url": "https://www.ebi.ac.uk/interpro/entry/IPR020003", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR022879", "url": "https://www.ebi.ac.uk/interpro/entry/IPR022879", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR027417", "url": "https://www.ebi.ac.uk/interpro/entry/IPR027417", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR055190", "url": "https://www.ebi.ac.uk/interpro/entry/IPR055190", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "bta:338059", "url": "https://www.genome.jp/dbget-bin/www_bget?bta:338059", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "YPRNYIR", "url": "https://omabrowser.org/oma/group/YPRNYIR/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "P31407", "url": "https://www.orthodb.org/?gene=P31407", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR43389", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR43389", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR43389:SF1", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR43389:SF1", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00006", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00006", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF02874", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF02874", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF22919", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF22919", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "R-BTA-1222556", "url": "https://www.reactome.org/PathwayBrowser/#R-BTA-1222556", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "R-BTA-77387", "url": "https://www.reactome.org/PathwayBrowser/#R-BTA-77387", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "R-BTA-917977", "url": "https://www.reactome.org/PathwayBrowser/#R-BTA-917977", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "R-BTA-9639288", "url": "https://www.reactome.org/PathwayBrowser/#R-BTA-9639288", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "R-BTA-983712", "url": "https://www.reactome.org/PathwayBrowser/#R-BTA-983712", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "NP_788827", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_788827", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A3Q1LT17", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1LT17", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A3Q1LT17-1", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1LT17-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0AAA9RWP7", "url": "https://www.uniprot.org/uniprotkb/A0AAA9RWP7", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0AAA9RWP7-1", "url": "https://www.uniprot.org/uniprotkb/A0AAA9RWP7-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0AAA9S9B3", "url": "https://www.uniprot.org/uniprotkb/A0AAA9S9B3", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0AAA9S9B3-1", "url": "https://www.uniprot.org/uniprotkb/A0AAA9S9B3-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0AAA9SB80", "url": "https://www.uniprot.org/uniprotkb/A0AAA9SB80", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0AAA9SB80-1", "url": "https://www.uniprot.org/uniprotkb/A0AAA9SB80-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0AAA9SYJ4", "url": "https://www.uniprot.org/uniprotkb/A0AAA9SYJ4", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0AAA9SYJ4-1", "url": "https://www.uniprot.org/uniprotkb/A0AAA9SYJ4-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0AAF6YVD1", "url": "https://www.uniprot.org/uniprotkb/A0AAF6YVD1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0AAF6YVD1-1", "url": "https://www.uniprot.org/uniprotkb/A0AAF6YVD1-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "P31407", "url": "https://www.uniprot.org/uniprotkb/P31407", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "P31407-1", "url": "https://www.uniprot.org/uniprotkb/P31407-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MAAEVDSRPRGLPGGGASLGAAREHVQAVTRNYITHPRITYRTVCSVNGPLVVLDQVKFAQYAEIVNFTLPNGTQRSGQVLEVSGTKAIVQVFEGTSGIDAQKTTCEFTGDILRTPVSEDMLGRVFNGSGKPIDKGPVVMAEDFLDINGQPINPHDRIYPEEMIETGISPIDVMNSIARGQKIPIFSAAGLPHNEIAAQICRQAGLVKKSKAVLDYHDDNFAIVFAAMGVNMETARFFKSDFEQNGTMGNVCLFLNLANDPTIERIITPRLALTTAEFLAYQCEKHVLVILTDMSSYAEALREVSAAREEVPGRRGFPGYMYTDLATIYERAGRVEGRGGSITQIPILTMPNDDITHPIPDLTGFITEGQIYVDRQLHNRQIYPPINVLPSLSRLMKSAIGEGMTRKDHGDVSNQLYACYAIGKDVQAMKAVVGEEALTSEDLLYLEFLQKFEKKFINQGPYEKRSVFESLDLGWKLLRTFPKEMLKRIPQNIIDEFFSREGAPQDTEADTAL", "length": 513, "header": "sp|P31407-1|VATB1_BOVIN Isoform 1 of V-type proton ATPase subunit B, kidney isoform OS=Bos taurus OX=9913 GN=ATP6V1B1 PE=1 SV=1 CANONICAL=P31407-1" }, "isoforms": [ { "isoform_ac": "A0A3Q1LT17-1", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1LT17/entry", "sequence": { "sequence": "QSLKFISKSVWAQDGRKELETGEGWGGDREECLSVSLSHCLSSLSLWAALPSYQFAQYAEIVNFTLPNGTQRSGQVLEVSGTKAIVQVFEGTSGIDAQKTTCEFTGDILRTPVSEDMLGRVFNGSGKPIDKGPVVMAEDFLDINGQPINPHDRIYPEEMIETGISPIDVMNSIARGQKIPIFSAAGLPHNEIAAQICRQAGLVKKSKAVLDYHDDNFAIVFAAMGVNMETARFFKSDFEQNGTMGNVCLFLNLANDPTIERIITPRLALTTAEFLAYQCEKHVLVILTDMSSYAEALREVSAAREEVPGRRGFPGYMYTDLATIYERAGRVEGRGGSITQIPILTMPNDDITHPIPDLTGFITEGQIYVDRQLHNRQIYPPINVLPSLSRLMKSAIGEGMTRKDHGDVSNQLYACYAIGKDVQAMKAVVGEEALTSEDLLYLEFLQKFEKKFINQGPYEKRSVFESLDLGWKLLRTFPKEMLKRIPQNIIDEFFSREGALVKH", "length": 503, "header": "tr|A0A3Q1LT17-1|A0A3Q1LT17_BOVIN Computationally mapped isoform of Vacuolar proton pump subunit B OS=Bos taurus OX=9913 GN=ATP6V1B1 PE=3 SV=1 CANONICAL=P31407-1" }, "locus": { "chromosome": "11", "start_pos": 13462181, "end_pos": 13454966, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000080915.1", "url": "https://www.ensembl.org/id/ENSBTAT00000080915.1" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000060176.1", "url": "https://www.ensembl.org/id/ENSBTAP00000060176.1" } ] } }, { "isoform_ac": "A0AAA9RWP7-1", "url": "https://www.uniprot.org/uniprotkb/A0AAA9RWP7/entry", "sequence": { "sequence": "MLWVREEGVAYRTVCSVNGPLVVLDQVKFAQYAEIVNFTLPNGTQRSGQVLEVSGTKAIVQVFEGTSGIDAQKTTCEFTGDILRTPVSEDMLGRVFNGSGKPIDKGPVVMAEDFLDINGQPINPHDRIYPEEMIETGISPIDVMNSIARGQKIPIFSAAGLPHNEIAAQICRQAGLVKKSKAVLDYHDDNFAIVFAAMGVNMETARFFKSDFEQNGTMGNVCLFLNLANDPTIERIITPRLALTTAEFLAYQCEKHVLVILTDMSSYAEALREVSAAREEVPGRRGFPGYMYTDLATIYERAGRVEGRGGSITQIPILTMPNDDITHPIPDLTGFITEGQIYVDRQLHNRQIYPPINVLPSLSRLMKSAIGEGMTRKDHGDVSNQLYACYAIGKDVQAMKAVVGEEALTSEDLLYLEFLQKFEKKFINQGPYEKRSVFESLDLGWKLLRTFPKEMLKRIPQNIIDEFFSREGAPQDTEADTAL", "length": 483, "header": "tr|A0AAA9RWP7-1|VATB1_BOVIN Computationally mapped isoform of V-type proton ATPase subunit B, kidney isoform OS=Bos taurus OX=9913 GN=ATP6V1B1 PE=1 SV=1 CANONICAL=P31407-1" }, "locus": { "chromosome": "11", "start_pos": 13473802, "end_pos": 13455255, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000092007.1", "url": "https://www.ensembl.org/id/ENSBTAT00000092007.1" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000075534.1", "url": "https://www.ensembl.org/id/ENSBTAP00000075534.1" } ] } }, { "isoform_ac": "A0AAA9S9B3-1", "url": "https://www.uniprot.org/uniprotkb/A0AAA9S9B3/entry", "sequence": { "sequence": "MVQPTGPCAASMGPWWCWIRSSLPSMLRLSTLPSPTGLSGVGKCSRCLGPRQLCRCLKGPLGLMPRRPPANSRGTSYGPQCQRTCWVRGRVFNGSGKPIDKGPVVMAEDFLDINGQPINPHDRIYPEEMIETGISPIDVMNSIARGQKIPIFSAAGLPHNEIAAQICRQAGLVKKSKAVLDYHDDNFAIVFAAMGVNMETARFFKSDFEQNGTMGNVCLFLNLANDPTIERIITPRLALTTAEFLAYQCEKHVLVILTDMSSYAEALREVSAAREEVPGRRGFPGYMYTDLATIYERAGRVEGRGGSITQIPILTMPNDDITHPIPDLTGFITEGQIYVDRQLHNRQIYPPINVLPSLSRLMKSAIGEGMTRKDHGDVSNQLYACYAIGKDVQAMKAVVGEEALTSEDLLYLEFLQKFEKKFINQGPYEKRSVFESLDLGWKLLRTFPKEMLKRIPQNIIDEFFSREGAPQDTEADTAL", "length": 479, "header": "tr|A0AAA9S9B3-1|VATB1_BOVIN Computationally mapped isoform of V-type proton ATPase subunit B, kidney isoform OS=Bos taurus OX=9913 GN=ATP6V1B1 PE=1 SV=1 CANONICAL=P31407-1" }, "locus": { "chromosome": "11", "start_pos": 13474690, "end_pos": 13455255, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000102941.1", "url": "https://www.ensembl.org/id/ENSBTAT00000102941.1" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000081877.1", "url": "https://www.ensembl.org/id/ENSBTAP00000081877.1" } ] } }, { "isoform_ac": "A0AAA9SB80-1", "url": "https://www.uniprot.org/uniprotkb/A0AAA9SB80/entry", "sequence": { "sequence": "MVRLEGREGGKRSLEGRCERSEPGNHLEVSASKAYRTVCSVNGPLVVLDQVKFAQYAEIVNFTLPNGTQRSGQVLEVSGTKAIVQVFEGTSGIDAQKTTCEFTGDILRTPVSEDMLGRVFNGSGKPIDKGPVVMAEDFLDINGQPINPHDRIYPEEMIETGISPIDVMNSIARGQKIPIFSAAGLPHNEIAAQICRQAGLVKKSKAVLDYHDDNFAIVFAAMGVNMETARFFKSDFEQNGTMGNVCLFLNLANDPTIERIITPRLALTTAEFLAYQCEKHVLVILTDMSSYAEALREVSAAREEVPGRRGFPGYMYTDLATIYERAGRVEGRGGSITQIPILTMPNDDITHPIPDLTGFITEGQIYVDRQLHNRQIYPPINVLPSLSRLMKSAIGEGMTRKDHGDVSNQLYACYAIGKDVQAMKAVVGEEALTSEDLLYLEFLQKFEKKFINQGPYEKRSVFESLDLGWKLLRTFPKEMLKRIPQNIIDEFFSREGAPQDTEADTAL", "length": 507, "header": "tr|A0AAA9SB80-1|VATB1_BOVIN Computationally mapped isoform of V-type proton ATPase subunit B, kidney isoform OS=Bos taurus OX=9913 GN=ATP6V1B1 PE=1 SV=1 CANONICAL=P31407-1" }, "locus": { "chromosome": "11", "start_pos": 13475233, "end_pos": 13455255, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000126849.1", "url": "https://www.ensembl.org/id/ENSBTAT00000126849.1" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000079446.1", "url": "https://www.ensembl.org/id/ENSBTAP00000079446.1" } ] } }, { "isoform_ac": "A0AAA9SYJ4-1", "url": "https://www.uniprot.org/uniprotkb/A0AAA9SYJ4/entry", "sequence": { "sequence": "MPTDSCSQFKLPPRCFNSHGSTIHASVAYRTVCSVNGPLVVLDQVKFAQYAEIVNFTLPNGTQRSGQVLEVSGTKAIVQVFEGTSGIDAQKTTCEFTGDILRTPVSEDMLGRVFNGSGKPIDKGPVVMAEDFLDINGQPINPHDRIYPEEMIETGISPIDVMNSIARGQKIPIFSAAGLPHNEIAAQICRQAGLVKKSKAVLDYHDDNFAIVFAAMGVNMETARFFKSDFEQNGTMGNVCLFLNLANDPTIERIITPRLALTTAEFLAYQCEKHVLVILTDMSSYAEALREVSAAREEVPGRRGFPGYMYTDLATIYERAGRVEGRGGSITQIPILTMPNDDITHPIPDLTGFITEGQIYVDRQLHNRQIYPPINVLPSLSRLMKSAIGEGMTRKDHGDVSNQLYACYAIGKDVQAMKAVVGEEALTSEDLLYLEFLQKFEKKFINQGPYEKRSVFESLDLGWKLLRTFPKEMLKRIPQNIIDEFFSREGAPQDTEADTAL", "length": 501, "header": "tr|A0AAA9SYJ4-1|VATB1_BOVIN Computationally mapped isoform of V-type proton ATPase subunit B, kidney isoform OS=Bos taurus OX=9913 GN=ATP6V1B1 PE=1 SV=1 CANONICAL=P31407-1" }, "locus": { "chromosome": "11", "start_pos": 13482189, "end_pos": 13455255, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000101950.2", "url": "https://www.ensembl.org/id/ENSBTAT00000101950.2" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000089164.1", "url": "https://www.ensembl.org/id/ENSBTAP00000089164.1" } ] } }, { "isoform_ac": "A0AAF6YVD1-1", "url": "https://www.uniprot.org/uniprotkb/A0AAF6YVD1/entry", "sequence": { "sequence": "MRRGSRKPERGHHSQPWERRGGWKEGWLPEEAGRLSPAPARLSCGRLRNPLPARHAMAAEVDSRPRGLPGGGASLGAAREHVQAVTRNYITHPRITYRTVCSVNGPLVVLDQVKFAQYAEIVNFTLPNGTQRSGQVLEVSGTKAIVQVFEGTSGIDAQKTTCEFTGDILRTPVSEDMLGRVFNGSGKPIDKGPVVMAEDFLDINGQPINPHDRIYPEEMIETGISPIDVMNSIARGQKIPIFSAAGLPHNEIAAQICRQAGLVKKSKAVLDYHDDNFAIVFAAMGVNMETARFFKSDFEQNGTMGNVCLFLNLANDPTIERIITPRLALTTAEFLAYQCEKHVLVILTDMSSYAEALREVSAAREEVPGRRGFPGYMYTDLATIYERAGRVEGRGGSITQIPILTMPNDDITHPIPDLTGFITEGQIYVDRQLHNRQIYPPINVLPSLSRLMKSAIGEGMTRKDHGDVSNQLYACYAIGKDVQAMKAVVGEEALTSEDLLYLEFLQKFEKKFINQGPYEKRSVFESLDLGWKLLRTFPKEMLKRIPQNIIDEFFSREGAPQDTEADTAL", "length": 569, "header": "tr|A0AAF6YVD1-1|A0AAF6YVD1_BOVIN Computationally mapped isoform of ATPase H+ transporting V1 subunit B1 OS=Bos taurus OX=9913 GN=ATP6V1B1 PE=3 SV=1 CANONICAL=P31407-1" }, "locus": { "chromosome": "11", "start_pos": 13482020, "end_pos": 13455255, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000014039.7", "url": "https://www.ensembl.org/id/ENSBTAT00000014039.7" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000014039.7", "url": "https://www.ensembl.org/id/ENSBTAP00000014039.7" } ] } }, { "isoform_ac": "P31407-1", "url": "https://www.uniprot.org/uniprotkb/P31407/entry#P31407-1", "sequence": { "sequence": "MAAEVDSRPRGLPGGGASLGAAREHVQAVTRNYITHPRITYRTVCSVNGPLVVLDQVKFAQYAEIVNFTLPNGTQRSGQVLEVSGTKAIVQVFEGTSGIDAQKTTCEFTGDILRTPVSEDMLGRVFNGSGKPIDKGPVVMAEDFLDINGQPINPHDRIYPEEMIETGISPIDVMNSIARGQKIPIFSAAGLPHNEIAAQICRQAGLVKKSKAVLDYHDDNFAIVFAAMGVNMETARFFKSDFEQNGTMGNVCLFLNLANDPTIERIITPRLALTTAEFLAYQCEKHVLVILTDMSSYAEALREVSAAREEVPGRRGFPGYMYTDLATIYERAGRVEGRGGSITQIPILTMPNDDITHPIPDLTGFITEGQIYVDRQLHNRQIYPPINVLPSLSRLMKSAIGEGMTRKDHGDVSNQLYACYAIGKDVQAMKAVVGEEALTSEDLLYLEFLQKFEKKFINQGPYEKRSVFESLDLGWKLLRTFPKEMLKRIPQNIIDEFFSREGAPQDTEADTAL", "length": 513, "header": "sp|P31407-1|VATB1_BOVIN Isoform 1 of V-type proton ATPase subunit B, kidney isoform OS=Bos taurus OX=9913 GN=ATP6V1B1 PE=1 SV=1 CANONICAL=P31407-1" }, "locus": {} } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [ { "title": "Selectively amplified expression of an isoform of the vacuolar H(+)-ATPase 56-kilodalton subunit in renal intercalated cells.", "journal": "Proc. Natl. Acad. Sci. U.S.A.", "date": "1992", "authors": "Nelson RD, Guo XL, Masood K, Brown D, Kalkbrenner M, Gluck S", "evidence": [ { "database": "UniProtKB", "id": "P31407", "url": "https://www.uniprot.org/uniprotkb/P31407" } ], "reference": [ { "type": "PubMed", "id": "1373501", "url": "https://glygen.org/publication/PubMed/1373501" } ] }, { "title": "Molecular identification, immunolocalization, and functional activity of a vacuolar-type H(+)-ATPase in bovine rumen epithelium.", "journal": "Journal of comparative physiology. 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"evidence": [ { "database": "Ensembl Gene", "id": "ENSBTAG00000018493", "url": "https://www.ensembl.org/id/ENSBTAG00000018493" } ] } } ], "crossref": [ { "id": "Q08DY0", "url": "https://alphafold.ebi.ac.uk/entry/Q08DY0", "database": "AlphaFoldDB", "categories": [] }, { "id": "ENSBTAG00000018493", "url": "https://bgee.org/?page=gene&gene_id=ENSBTAG00000018493", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "504339", "url": "https://www.ncbi.nlm.nih.gov/gene/504339", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR027856", "url": "https://www.ebi.ac.uk/interpro/entry/IPR027856", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "bta:504339", "url": "https://www.genome.jp/dbget-bin/www_bget?bta:504339", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "PKPCTLG", "url": "https://omabrowser.org/oma/group/PKPCTLG/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "A0A3Q1LIH9", "url": "https://www.orthodb.org/?gene=A0A3Q1LIH9", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "Q08DY0", "url": "https://www.orthodb.org/?gene=Q08DY0", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR23006", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR23006", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR23006:SF0", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR23006:SF0", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF27861", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF27861", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "NP_001071312", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001071312", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A3Q1LIH9", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1LIH9", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A3Q1LIH9-1", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1LIH9-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0AAA9TNH9", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TNH9", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0AAA9TNH9-1", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TNH9-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0AAA9TQZ1", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TQZ1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0AAA9TQZ1-1", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TQZ1-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0AAA9TWX7", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TWX7", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0AAA9TWX7-1", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TWX7-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0AAF7A9Q5", "url": "https://www.uniprot.org/uniprotkb/A0AAF7A9Q5", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0AAF7A9Q5-1", "url": "https://www.uniprot.org/uniprotkb/A0AAF7A9Q5-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "Q08DY0", "url": "https://www.uniprot.org/uniprotkb/Q08DY0", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "Q08DY0-1", "url": "https://www.uniprot.org/uniprotkb/Q08DY0-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MGCSSSALNKAGDDNRLRSATEESESCFVQPKPRALGRESTLCGKVQKESLPPLDKLKISAVSTANGVQSLPEQPLAKEAADPPGATEETQPLQGLKGSEPPQPGGKDGAPGAEGKEEDVEAVTEAPPLKGSAETEPLGAEAENQPLITAGERDSTGAVEGTEDPQAAGEMTPLGTAERVPLEAAREPGSQEAGGKGEQSQLPETVPKETESPEILEGSQPVETAEPPQLQETVGENEQSQPLETVPKENASLEVSDGSQSVGAEGKKQLQETLGENEQSQLRETILGEHGGPEVSDGSQSVGAEEEKRLQEMLGKDEQPQLRETIPREHGGPEMSDASQSVETAVKADSLHKAPEGPGNMEKIQPERTVESMEHPAGILETGAKVEMARKIHTNEEDQHIEGETGETVETEMESEKVSEGAETKEEETGEAMDLSAATQIGMDGRVKGHSML", "length": 453, "header": "sp|Q08DY0-1|ERIC5_BOVIN Isoform 1 of Glutamate-rich protein 5 OS=Bos taurus OX=9913 GN=ERICH5 PE=2 SV=1 CANONICAL=Q08DY0-1" }, "isoforms": [ { "isoform_ac": "A0A3Q1LIH9-1", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1LIH9/entry", "sequence": { "sequence": "MGCSSSALNKAGDDNRLRSEESESCFVQPKPRALGRESTLCGKVQKESLPPLDKLKISAVSTANGVQSLPEQPLAKEAADPPGATEETQPLQGLKGSEPPQPGGKDGAPGAEGKEEDVEAVTEAPPLKGSAETEPLGAEAENQPLITAGERDSTGAVEGTEDPQAAGEMTPLGTAERVPLEAAREPGSQEAGGKGEQSQLPETVPKETESPEILEGSQPVETAEPPQLQETVGENEQSQPLETVPKENASLEVSDGSQSVGAEGKKQLQETLGENEQSQLRETILGEHGGPEVSDGSQSVGAEEEKRLQEMLGKDEQPQLRETIPREHGGPEMSDASQSVETAVKADSLHKAPEGPGNMEKIQPERTVESMEHPAGILETGAKVEMARKIHTNEEDQHIEGETGETVETEMESEKVSEGAETKEEETGEAMDLSAATQIDSKCRSWIKT", "length": 449, "header": "tr|A0A3Q1LIH9-1|ERIC5_BOVIN Computationally mapped isoform of Glutamate-rich protein 5 OS=Bos taurus OX=9913 GN=ERICH5 PE=2 SV=2 CANONICAL=Q08DY0-1" }, "locus": { "chromosome": "14", "start_pos": 66162839, "end_pos": 66136474, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000083997.2", "url": "https://www.ensembl.org/id/ENSBTAT00000083997.2" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000058850.2", "url": "https://www.ensembl.org/id/ENSBTAP00000058850.2" } ] } }, { "isoform_ac": "A0AAA9TNH9-1", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TNH9/entry", "sequence": { "sequence": "MGCSSSALNKAGDDNRLRSATEESESCFVQPKPRALGRESTLCGKVQKESLPPLDKLKISAVSTANGVQSLPEQPLAKEAADPPGATEETQPLQGLKGSEPPQPGGKDGAPGAEGKEEDVEAVTEAPPLKGSAETEPLGAEAENQPLITAGERDSTGAVEGTEDPQAAGEMTPLGTAERVPLEAAREPGSQEAGGKGEQSQLPETVPKETESPEILEGSQPVETAEPPQLQETVGENEQSQPLETVPKENASLEVSDGSQSVGAEGKKQLQETLGENEQSQLRETILGEHGGPEMSDASQSVETAVKADSLHKAPEGPGNMEKIQPERTVESMEHPAGILETGAKVEMARKIHTNEEDQHIEGETGETVETEMESEKVSEGAETKEEETGEAMDLSAATQIGMDGRVKGHSML", "length": 413, "header": "tr|A0AAA9TNH9-1|ERIC5_BOVIN Computationally mapped isoform of Glutamate-rich protein 5 OS=Bos taurus OX=9913 GN=ERICH5 PE=2 SV=1 CANONICAL=Q08DY0-1" }, "locus": { "chromosome": "14", "start_pos": 66162839, "end_pos": 66139125, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000125928.1", "url": "https://www.ensembl.org/id/ENSBTAT00000125928.1" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000097897.1", "url": "https://www.ensembl.org/id/ENSBTAP00000097897.1" } ] } }, { "isoform_ac": "A0AAA9TQZ1-1", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TQZ1/entry", "sequence": { "sequence": "MGCSSSALNKAGDDNRLRSATEESESCFVQPKPRALGRESTLCGKVQKESLPPLDKLKISAVSTANGVQSLPEQPLAKEAADPPGATEETQPLQGLKGSEPPQPGGKDGAPGAEGKEEDVEAVTEAPPLKGSAETEPLGAEAENQPLITAGERDSTGAVEGTEDPQAAGEMTPLGTAERVPLEAAREPGSQEAGGKGEQSQLPETVPKETESPEILEGSQPVETAEPPQLQETVGENEQSQPLETVPKENASLEVSDGSQSVGAEGKKQLQETLGENEQSQLRETILGEHGGPEVSDGSQSVGAEEEKRLQEMLGKDEQPQLRETIPREHGGPEMSDASQSVETAVKADSLHKAPEGPGNMEKIQPERTVESMEHPAGILETGAKVEMARKIHTNEEDQHIEGETGETVETEMESEKVSEGAETKEEETGEAMDLSAATQIGM", "length": 443, "header": "tr|A0AAA9TQZ1-1|ERIC5_BOVIN Computationally mapped isoform of Glutamate-rich protein 5 OS=Bos taurus OX=9913 GN=ERICH5 PE=2 SV=1 CANONICAL=Q08DY0-1" }, "locus": { "chromosome": "14", "start_pos": 66162839, "end_pos": 66136336, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000101764.1", "url": "https://www.ensembl.org/id/ENSBTAT00000101764.1" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000099428.1", "url": "https://www.ensembl.org/id/ENSBTAP00000099428.1" } ] } }, { "isoform_ac": "A0AAA9TWX7-1", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TWX7/entry", "sequence": { "sequence": "MGCSSSALNKAGDDNRLRSATEESESCFVQPKPRALGRESTLCGKVQKESLPPLDKLKISAVSTANGVQSLPEQPLAKEAADPPGATEETQPLQGLKGSEPPQPGGKDGAPGAEGKEEDVEAVTEAPPLKGSAETEPLGAEAENQPLITAGERDSTGAVEGTEDPQAAGEMTPLGTAERVPLEAAREPGSQEAGGKGEQSQLPETVPKETESPEILEGSQPVETAEPPQLQETVGENEQSQPLETVPKENASLEVSDGSQSVGAEGKKQLQETLGENEQSQLRETILGEHGGPEVSDGSQSVGAEEEKRLQEMLGKDEQPQLRETIPREHGGPEMSDASQSVETAVKADSLHKAPEGPGNMEKIQPERTVESMEHPAGILETGAKVEMARKIHTNEEDQHIEGETGETVETEMESEKVSEGAETKEEETGEAMDLSAATQIVLVTSSKS", "length": 449, "header": "tr|A0AAA9TWX7-1|A0AAA9TWX7_BOVIN Computationally mapped isoform of Glutamate rich 5 OS=Bos taurus OX=9913 GN=ERICH5 PE=4 SV=1 CANONICAL=Q08DY0-1" }, "locus": { "chromosome": "14", "start_pos": 66162839, "end_pos": 66134858, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000131146.1", "url": "https://www.ensembl.org/id/ENSBTAT00000131146.1" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000101096.1", "url": "https://www.ensembl.org/id/ENSBTAP00000101096.1" } ] } }, { "isoform_ac": "A0AAF7A9Q5-1", "url": "https://www.uniprot.org/uniprotkb/A0AAF7A9Q5/entry", "sequence": { "sequence": "MGILQARILAWVAISFCRGSSDSEVESKSALKADFFFLNRWSRQVLQPSGLKSHLAVFCCSEAARCGTQESGTGRELEKPTESEAEGVLRRGGVWTSASVPQSAPLPEAPALRRRGEDPATEESESCFVQPKPRALGRESTLCGKVQKESLPPLDKLKISAVSTANGVQSLPEQPLAKEAADPPGATEETQPLQGLKGSEPPQPGGKDGAPGAEGKEEDVEAVTEAPPLKGSAETEPLGAEAENQPLITAGERDSTGAVEGTEDPQAAGEMTPLGTAERVPLEAAREPGSQEAGGKGEQSQLPETVPKETESPEILEGSQPVETAEPPQLQETVGENEQSQPLETVPKENASLEVSDGSQSVGAEGKKQLQETLGENEQSQLRETILGEHGGPEVSDGSQSVGAEEEKRLQEMLGKDEQPQLRETIPREHGGPEMSDASQSVETAVKADSLHKAPEGPGNMEKIQPERTVESMEHPAGILETGAKVEMARKIHTNEEDQHIEGETGETVETEMESEKVSEGAETKEEETGEAMDLSAATQIGM", "length": 543, "header": "tr|A0AAF7A9Q5-1|A0AAF7A9Q5_BOVIN Computationally mapped isoform of Glutamate rich 5 OS=Bos taurus OX=9913 GN=ERICH5 PE=4 SV=1 CANONICAL=Q08DY0-1" }, "locus": { "chromosome": "14", "start_pos": 66176090, "end_pos": 66136336, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000069699.2", "url": "https://www.ensembl.org/id/ENSBTAT00000069699.2" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000065170.2", "url": "https://www.ensembl.org/id/ENSBTAP00000065170.2" } ] } }, { "isoform_ac": "Q08DY0-1", "url": "https://www.uniprot.org/uniprotkb/Q08DY0/entry#Q08DY0-1", "sequence": { "sequence": "MGCSSSALNKAGDDNRLRSATEESESCFVQPKPRALGRESTLCGKVQKESLPPLDKLKISAVSTANGVQSLPEQPLAKEAADPPGATEETQPLQGLKGSEPPQPGGKDGAPGAEGKEEDVEAVTEAPPLKGSAETEPLGAEAENQPLITAGERDSTGAVEGTEDPQAAGEMTPLGTAERVPLEAAREPGSQEAGGKGEQSQLPETVPKETESPEILEGSQPVETAEPPQLQETVGENEQSQPLETVPKENASLEVSDGSQSVGAEGKKQLQETLGENEQSQLRETILGEHGGPEVSDGSQSVGAEEEKRLQEMLGKDEQPQLRETIPREHGGPEMSDASQSVETAVKADSLHKAPEGPGNMEKIQPERTVESMEHPAGILETGAKVEMARKIHTNEEDQHIEGETGETVETEMESEKVSEGAETKEEETGEAMDLSAATQIGMDGRVKGHSML", "length": 453, "header": "sp|Q08DY0-1|ERIC5_BOVIN Isoform 1 of Glutamate-rich protein 5 OS=Bos taurus OX=9913 GN=ERICH5 PE=2 SV=1 CANONICAL=Q08DY0-1" }, "locus": { "chromosome": "14", "start_pos": 66162839, "end_pos": 66139125, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000024611.6", "url": "https://www.ensembl.org/id/ENSBTAT00000024611.6" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000024611.4", "url": "https://www.ensembl.org/id/ENSBTAP00000024611.4" } ] } } ], "glycosylation": [], "phosphorylation": [ { "start_pos": 155, "end_pos": 155, "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "residue": "Ser", "comment": "Phosphoserine", "evidence": [ { "database": "UniProtKB", "id": "Q08DY0", "url": "https://www.uniprot.org/uniprotkb/Q08DY0" } ], "site_lbl": "Ser155" } ], "glycation": [], "keywords": [], "publication": [], "pathway": [ { "id": "bta:504339", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?bta:504339", "resource": "KEGG Pathway" } ], "orthologs": [ { "uniprot_canonical_ac": "F1M6T7-1", "protein_name": "Glutamate-rich 5", "gene_name": "Erich5", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MWPRDVVPGRPRDAALPLEAISVHLPLIFLLAALPSNENSSTVEQNKFCVAQPKPCTPGREAAFRGNAQKESHPPLERPKASVVPTANGVKSYHQLSLANDEISGKEATDQSRPTKKTEPLVQGGECELPQPGGKDDTLGTEEVKKDVEARAEVQALPGKAETEPLRMPAERDAPGAGEDIELPQAGTTKFLQTAENILSLETAQELPPEEAMGRDKQPQVLEAIPKENSSPEIAEGSQSAENGEKQQLSEAPGEAEQPQVLEIVLRENETPQMPDGSQLVPTPVMNDSPCEAPDGVRNESQVTRENRVHPVGTAETAAEVEMTREIHPDKEEPHIEGETGENVEAEMKNEEESEEAETKEKETGEAVDPGVAGAGDRRA", "length": 380 }, "evidence": [ { "id": "Q08DY0", "url": "https://omabrowser.org/oma/group/Q08DY0/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "Q6P6B1-1", "protein_name": "Glutamate-rich protein 5", "gene_name": "ERICH5", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MGCSSSALNKAGDSSRFPSVTSNEHFSTAEESESCFAQPKPHALGRESTVDGNVQRESRPPLQKLKVSAEPTANGVKPLQEQPLAKDVAPGRDATDQSGSTEKTQPGEGLEESGPPQPGGKEDAPAAEGKKKDAGAGTEAESLKGNAEAQPLGPEAKGQPLQAAVEKDSLRAVEVTENPQTAAEMKPLGTTENVLTLQIAGELQPQGTVGKDEQAPLLETISKENESPEILEGSQFVETAEEQQLQATLGKEEQPQLLERIPKENVTPEVLDRSQLVEKPVMNDPFHKTPEGPGNMEQIQPEGIVGSMEHPARNVEAGAYVEMIRNIHTNEEDQRIEGETGEKVETDMENEKVSEGAETKEEETGEVVDLSAAT", "length": 374 }, "evidence": [ { "id": "Q08DY0", "url": "https://omabrowser.org/oma/group/Q08DY0/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "Q8K0S2-1", "protein_name": "Glutamate-rich protein 5", "gene_name": "Erich5", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MGCSSSALNKAGDSSRFGSGVTSNENSSTVEHNKFCVDQPKPCTPGGEAAFHGNTQRESHPSLERPKASVVPTANGVKSYHQPSLANDETPGKEATDHSRPTKKIEPLVQGGECEQPQPGGKDDMLGTEEVKKDVEARTEVPSLKGDAEIKPLRLSSERDSPGAPQAGTMKFLQTAENILPLETTQELPPKEATGKGAQPQILEAIPKENSSPEIEGIQSAESSGQQQLVEAPGEAEQPQALETVLKENETSQMPGRSQPVPTPVMNKSPCEAPDGLRNAHEPQVTGGNRVQPAETGETAAKVEMAREIHPDKEEQHIEGETGEKVEAEMKNEKESEEAETKEKETGEAVDLGAAGAGDRRA", "length": 362 }, "evidence": [ { "id": "Q08DY0", "url": "https://omabrowser.org/oma/group/Q08DY0/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" } ], "go_annotation": {}, "pro_annotation": [], "site_annotation": [ { "start_pos": 250, "end_pos": 252, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [ { "pdb_id": "AF-Q08DY0-F1", "pdb_chain": "global", "start_pos": 1, "end_pos": 453, "overlap": "1.0", "method": "AlphaFold", "type": "alphafold", "resolution": -1.0, "url": "https://data.glygen.org/ln2downloads/pdb/current/AF-Q08DY0-F1.pdb", "url_external": "https://alphafold.ebi.ac.uk/entry/Q08DY0" } ], "lectin_list": [], "domain_list": [], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" }, { "name": "homologset.oma", "label": "OMA Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [ 155 ], "sequon_annotation_sites": [ { "start_pos": 250, "end_pos": 252 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 1 }, { "field": "total_sites", "count": 1 } ], "sort_fields": [ "start_pos", "end_pos", "kinase_uniprot_canonical_ac", "kinase_gene_name", "residue", "comment", "site_lbl" ] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ], "tool_support": { "graph_view": "yes" } }, { "uniprot_canonical_ac": "Q32LF5-1", "uniprot_ac": "Q32LF5", "uniprot_id": "CA052_BOVIN", "mass": { "chemical_mass": 20552.0, "monoisotopic_mass": 20552.0 }, "refseq": { "ac": "NP_001032681", "name": "UPF0690 protein C1orf52 homolog", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001032681" }, "gene_names": [ { "name": "C3H1orf52", "type": "recommended", "evidence": [ { "id": "Q32LF5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q32LF5" } ] }, { "name": "C1orf52", "type": "synonym", "evidence": [ { "id": "NP_001032681", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001032681" } ] }, { "name": "C3H1orf52", "type": "synonym", "evidence": [ { "id": "NP_001032681", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001032681" } ] } ], "protein_names": [ { "name": "UPF0690 protein C1orf52 homolog", "type": "recommended", "evidence": [ { "id": "Q32LF5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q32LF5/entry#names_and_taxonomy" } ] }, { "name": "UPF0690 protein C1orf52 homolog", "type": "synonym", "evidence": [ { "id": "NP_001032681", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001032681" } ] } ], "function": [], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Bos taurus", "taxid": 9913, "evidence": [ { "database": "UniProtKB", "id": "Q32LF5", "url": "https://www.uniprot.org/uniprotkb/Q32LF5" } ], "common_name": "Bovine", "glygen_name": "Bovine", "reference_species": "Bos taurus [9913]" } ], "gene": [ { "name": "", "url": "https://www.uniprot.org/uniprotkb/Q32LF5", "locus": {} } ], "crossref": [ { "id": "Q32LF5", "url": "https://alphafold.ebi.ac.uk/entry/Q32LF5", "database": "AlphaFoldDB", "categories": [] }, { "id": "ENSBTAG00000016326", "url": "https://bgee.org/?page=gene&gene_id=ENSBTAG00000016326", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "509947", "url": "https://www.ncbi.nlm.nih.gov/gene/509947", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR029089", "url": "https://www.ebi.ac.uk/interpro/entry/IPR029089", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "bta:509947", "url": "https://www.genome.jp/dbget-bin/www_bget?bta:509947", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "PERICEP", "url": "https://omabrowser.org/oma/group/PERICEP/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "Q32LF5", "url": "https://www.orthodb.org/?gene=Q32LF5", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR31833", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR31833", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR31833:SF2", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR31833:SF2", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF15559", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF15559", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "NP_001032681", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001032681", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A3Q1LKI6", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1LKI6", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A3Q1LKI6-1", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1LKI6-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0AAF6Z2U9", "url": "https://www.uniprot.org/uniprotkb/A0AAF6Z2U9", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0AAF6Z2U9-1", "url": "https://www.uniprot.org/uniprotkb/A0AAF6Z2U9-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0ABI0NK74", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NK74", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0ABI0NK74-1", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NK74-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "Q32LF5", "url": "https://www.uniprot.org/uniprotkb/Q32LF5", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "Q32LF5-1", "url": "https://www.uniprot.org/uniprotkb/Q32LF5-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MAAEEKDPLSYFAAYGSSSSGSSDEEDNSEPEETSRKGQDTAKSAGGYGNKAEKRLPGPDELFRSVTRPAFLYNPLNKQIDWERHVVKAPEEPPKEFKIWKSHYVPPPETYSTEKKPPPPELDMAIKWSNIYEDNGDDAPQNAKKARLLPEGEETVESDDEKDEHTSKKRKIELGEPTKKKK", "length": 182, "header": "sp|Q32LF5-1|CA052_BOVIN Isoform 1 of UPF0690 protein C1orf52 homolog OS=Bos taurus OX=9913 GN= PE=2 SV=1 CANONICAL=Q32LF5-1" }, "isoforms": [ { "isoform_ac": "A0A3Q1LKI6-1", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1LKI6/entry", "sequence": { "sequence": "MSIRTPCLGTCGQPSASVPEAGRKNATQPPGGADLGPVSETWGGVSCGAGPGVTSGFRRSRGRTGAAVMAAEEKDPLSYFAAYGSSSSGSSDEEDNSEPEETSRKGQDTAKSAGGYGNKAEKRLPGPDELFRSVTRPAFLYNPLNKQIDWERHVVKAPEEPPKEFKIWKSHYVPPPETYSTEKKPPPPELDMAIKWSNIYEDNGDDAPQNAKKARLLPEGEETVESGGEEACFFLPLEYSDSPGNGGESRTTYIGQN", "length": 257, "header": "tr|A0A3Q1LKI6-1|CA052_BOVIN Computationally mapped isoform of UPF0690 protein C1orf52 homolog OS=Bos taurus OX=9913 GN= PE=2 SV=2 CANONICAL=Q32LF5-1" }, "locus": { "chromosome": "3", "start_pos": 58842059, "end_pos": 58835774, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000084239.3", "url": "https://www.ensembl.org/id/ENSBTAT00000084239.3" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000057188.2", "url": "https://www.ensembl.org/id/ENSBTAP00000057188.2" } ] } }, { "isoform_ac": "A0AAF6Z2U9-1", "url": "https://www.uniprot.org/uniprotkb/A0AAF6Z2U9/entry", "sequence": { "sequence": "MSIRTPCLGTCGQPSASVPEAGRKNATQPPGGADLGPVSETWGGVSCGAGPGVTSGFRRSRGRTGAAVMAAEEKDPLSYFAAYGSSSSGSSDEEDNSEPEETSRKGQDTAKSAGGYGNKAEKRLPGPDELFRSVTRPAFLYNPLNKQIDWERHVVKAPEEPPKEFKIWKSHYVPPPETYSTEKKPPPPELDMAIKWSNIYEDNGDDAPQNAKKARLLPEGEETVESDDEKDEHTSKKRKIELGEPTKKKK", "length": 250, "header": "tr|A0AAF6Z2U9-1|A0AAF6Z2U9_BOVIN Computationally mapped isoform of Chromosome 3 C1orf52 homolog OS=Bos taurus OX=9913 GN=C3H1orf52 PE=3 SV=1 CANONICAL=Q32LF5-1" }, "locus": { "chromosome": "3", "start_pos": 58842588, "end_pos": 58835774, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000021717.5", "url": "https://www.ensembl.org/id/ENSBTAT00000021717.5" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000021717.4", "url": "https://www.ensembl.org/id/ENSBTAP00000021717.4" } ] } }, { "isoform_ac": "A0ABI0NK74-1", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NK74/entry", "sequence": { "sequence": "MSIRTPCLGTCGQPSASVPEAGRKNATQPPGGADLGPVSETWGGVSCGAGPGVTSGFRRSRGRTGAAVMAAEEKDPLSYFAAYGSSSSGSSDEEDNSEPEETSRKGQDTAKSAGGYGNKAEKRLPGPDELFRSVTRPAFLYNPLNKQIDWERHVVKAPEEPPKEFKIWKSHYVPPPETYSTEKKPPPPELDMAIKWSNIYEDNGDDAPQNAKKARLLPEGEETVESGKECQIPVVIPFDPCDEF", "length": 244, "header": "tr|A0ABI0NK74-1|A0ABI0NK74_BOVIN Computationally mapped isoform of Chromosome 3 C1orf52 homolog OS=Bos taurus OX=9913 GN=C3H1orf52 PE=3 SV=1 CANONICAL=Q32LF5-1" }, "locus": { "chromosome": "3", "start_pos": 58837138, "end_pos": 58835774, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000146407.1", "url": "https://www.ensembl.org/id/ENSBTAT00000146407.1" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000105038.1", "url": "https://www.ensembl.org/id/ENSBTAP00000105038.1" } ] } }, { "isoform_ac": "Q32LF5-1", "url": "https://www.uniprot.org/uniprotkb/Q32LF5/entry#Q32LF5-1", "sequence": { "sequence": "MAAEEKDPLSYFAAYGSSSSGSSDEEDNSEPEETSRKGQDTAKSAGGYGNKAEKRLPGPDELFRSVTRPAFLYNPLNKQIDWERHVVKAPEEPPKEFKIWKSHYVPPPETYSTEKKPPPPELDMAIKWSNIYEDNGDDAPQNAKKARLLPEGEETVESDDEKDEHTSKKRKIELGEPTKKKK", "length": 182, "header": "sp|Q32LF5-1|CA052_BOVIN Isoform 1 of UPF0690 protein C1orf52 homolog OS=Bos taurus OX=9913 GN= PE=2 SV=1 CANONICAL=Q32LF5-1" }, "locus": {} } ], "glycosylation": [], "phosphorylation": [ { "start_pos": 132, "end_pos": 132, "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "residue": "Tyr", "comment": "Phosphotyrosine", "evidence": [ { "database": "UniProtKB", "id": "Q32LF5", "url": "https://www.uniprot.org/uniprotkb/Q32LF5" } ], "site_lbl": "Tyr132" }, { "start_pos": 158, "end_pos": 158, "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "residue": "Ser", "comment": "Phosphoserine", "evidence": [ { "database": "UniProtKB", "id": "Q32LF5", "url": "https://www.uniprot.org/uniprotkb/Q32LF5" } ], "site_lbl": "Ser158" }, { "start_pos": 67, "end_pos": 67, "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "residue": "Thr", "comment": "Phosphothreonine", "evidence": [ { "database": "UniProtKB", "id": "Q32LF5", "url": "https://www.uniprot.org/uniprotkb/Q32LF5" } ], "site_lbl": "Thr67" } ], "glycation": [], "keywords": [], "publication": [], "pathway": [ { "id": "bta:509947", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?bta:509947", "resource": "KEGG Pathway" } ], "orthologs": [ { "uniprot_canonical_ac": "A0A8I6AL75-1", "protein_name": "Similar to human chromosome 1 open reading frame 52", "gene_name": "C2h1orf52", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MAAEEKDPLSYFAAYGSSSSDSSDEENSEPEDAGRKEAAPAPTTGGRGKQAEKRLPGPDELFRSVTRPAFLYNPLNKQIDWERHVVKAPEEPPKEFKIWKSNCVPPPETYTAEKKPPPPELDMAIKWSNIYEDNGDDAPQNAKKARLLPEGEETVESDDDRDERASKTRRVEPGEAAKKKK", "length": 181 }, "evidence": [ { "id": "Q32LF5", "url": "https://omabrowser.org/oma/group/Q32LF5/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "Q7SZP2-1", "protein_name": "UPF0690 protein C1orf52 homolog", "gene_name": "", "tax_id": 7955, "organism": "Danio rerio", "sequence": { "sequence": "MSDEEKSETRNFFMGYDDLSDSSSDSESRSGPEATASSAPAEPQQSRKRAAEPLPRPDELFRSVSKPAFLYNPLNKAIDWDSRAVRAPEEPPKEFKVWKSSAVPPPQSYVTEENKKKAPAGMDMAIKWSNVYEDNGDDAPQAHRGPAHFLPEEEEEEQQPDSDDDSSSKLSKSAKKRRVETFQQKEKRKRDIGQATSDKNFVEEEKRILRQCLD", "length": 214 }, "evidence": [ { "id": "Q32LF5", "url": "https://omabrowser.org/oma/group/Q32LF5/", "database": "OMA" } ], "glygen_name": "Zebrafish", "common_name": "Zebrafish" }, { "uniprot_canonical_ac": "Q9CWU4-1", "protein_name": "UPF0690 protein C1orf52 homolog", "gene_name": "", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MAAEEKDPLSYFAAYGSSSSDSSDENSEPEDAGRKEAASAPTTGGRGKQAEKRLPGPDELFRSVTRPAFLYNPLNKQIDWERHVVKAPEEPPKEFKIWKSNCVPPPETYTTEKKPPPPELDMAIKWSNIYEDNGDDAPQNAKKARLLPEGEETVESDDDKDERASKIRRVEPGEAAKKKK", "length": 180 }, "evidence": [ { "id": "Q32LF5", "url": "https://omabrowser.org/oma/group/Q32LF5/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" } ], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 1, "go_terms": [ { "name": "nucleoplasm", "id": "GO:0005654", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005654", "evidence": [ { "database": "UniProtKB", "id": "Q32LF5", "url": "https://www.uniprot.org/uniprotkb/Q32LF5" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [ { "pdb_id": "AF-Q32LF5-F1", "pdb_chain": "global", "start_pos": 1, "end_pos": 182, "overlap": "1.0", "method": "AlphaFold", "type": "alphafold", "resolution": -1.0, "url": "https://data.glygen.org/ln2downloads/pdb/current/AF-Q32LF5-F1.pdb", "url_external": "https://alphafold.ebi.ac.uk/entry/Q32LF5" } ], "lectin_list": [], "domain_list": [], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" }, { "name": "homologset.oma", "label": "OMA Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [ 67, 132, 158 ], "sequon_annotation_sites": [] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 3 }, { "field": "total_sites", "count": 3 } ], "sort_fields": [ "start_pos", "end_pos", "kinase_uniprot_canonical_ac", "kinase_gene_name", "residue", "comment", "site_lbl" ] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ], "tool_support": { "graph_view": "yes" } }, { "uniprot_canonical_ac": "Q2KI24-1", "uniprot_ac": "Q2KI24", "uniprot_id": "MTHSD_BOVIN", "mass": { "chemical_mass": 41483.0, "monoisotopic_mass": 41483.0 }, "refseq": { "ac": "NP_001039507", "name": "methenyltetrahydrofolate synthase domain-containing protein", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001039507" }, "gene_names": [ { "name": "MTHFSD", "type": "recommended", "evidence": [ { "id": "Q2KI24", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q2KI24" } ] }, { "name": "MTHFSD", "type": "synonym", "evidence": [ { "id": "NP_001039507", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001039507" } ] } ], "protein_names": [ { "name": "Methenyltetrahydrofolate synthase domain-containing protein", "type": "recommended", "evidence": [ { "id": "Q2KI24", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q2KI24/entry#names_and_taxonomy" } ] }, { "name": "methenyltetrahydrofolate synthase domain-containing protein", "type": "synonym", "evidence": [ { "id": "NP_001039507", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001039507" } ] }, { "name": "methenyltetrahydrofolate synthetase domain-containing protein", "type": "synonym", "evidence": [ { "id": "NP_001039507", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001039507" } ] } ], "function": [], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Bos taurus", "taxid": 9913, "evidence": [ { "database": "UniProtKB", "id": "Q2KI24", "url": "https://www.uniprot.org/uniprotkb/Q2KI24" } ], "common_name": "Bovine", "glygen_name": "Bovine", "reference_species": "Bos taurus [9913]" } ], "gene": [ { "name": "MTHFSD", "url": "https://www.uniprot.org/uniprotkb/Q2KI24", "locus": { "chromosome": "18", "start_pos": 12356267, "end_pos": 12374006, "strand": "+", "evidence": [ { "database": "Ensembl Gene", "id": "ENSBTAG00000012446", "url": "https://www.ensembl.org/id/ENSBTAG00000012446" } ] } } ], "crossref": [ { "id": "Q2KI24", "url": "https://alphafold.ebi.ac.uk/entry/Q2KI24", "database": "AlphaFoldDB", "categories": [] }, { "id": "ENSBTAG00000012446", "url": "https://bgee.org/?page=gene&gene_id=ENSBTAG00000012446", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "509897", "url": "https://www.ncbi.nlm.nih.gov/gene/509897", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR000504", "url": "https://www.ebi.ac.uk/interpro/entry/IPR000504", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR002698", "url": "https://www.ebi.ac.uk/interpro/entry/IPR002698", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR012677", "url": "https://www.ebi.ac.uk/interpro/entry/IPR012677", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR024185", "url": "https://www.ebi.ac.uk/interpro/entry/IPR024185", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR035979", "url": "https://www.ebi.ac.uk/interpro/entry/IPR035979", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR037171", "url": "https://www.ebi.ac.uk/interpro/entry/IPR037171", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "bta:509897", "url": "https://www.genome.jp/dbget-bin/www_bget?bta:509897", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "VIRTECK", "url": "https://omabrowser.org/oma/group/VIRTECK/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "A0A3Q1LKN7", "url": "https://www.orthodb.org/?gene=A0A3Q1LKN7", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A3Q1MHY5", "url": "https://www.orthodb.org/?gene=A0A3Q1MHY5", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "Q2KI24", "url": "https://www.orthodb.org/?gene=Q2KI24", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR13017", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR13017", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR13017:SF0", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR13017:SF0", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00076", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00076", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF01812", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF01812", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "NP_001039507", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001039507", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A3Q1LKN7", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1LKN7", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A3Q1LKN7-1", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1LKN7-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A3Q1MHY5", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1MHY5", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A3Q1MHY5-1", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1MHY5-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0AAF6ZB28", "url": "https://www.uniprot.org/uniprotkb/A0AAF6ZB28", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0AAF6ZB28-1", "url": "https://www.uniprot.org/uniprotkb/A0AAF6ZB28-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "Q2KI24", "url": "https://www.uniprot.org/uniprotkb/Q2KI24", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "Q2KI24-1", "url": "https://www.uniprot.org/uniprotkb/Q2KI24-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MEPRAGVSKQDIREQIWDYMESQNLADFPRPVHHRIPNFKGASRAAEHFPRLQAFKMARTIKVNPDAPQKNARFFVLESKKTLLVPTPRLRTGLFNKITPPPGATKDILRKCATSQGVRNYSTPVGLDSKVLVDLVVVGSVAVSEKGWRIGKGEGYADLEYAMMVSMGAVSQGTPVVTIVHDCQVVDIPEALLEDHDLTVDYILTPTRVITTGCERPKPAGIAWSKISCEMLGKMPILRSLRHQEEQAGKDVTLRDGPRSPPGATRSPRDLAPPELGSVPLSSVQIGNLPRDARVSELKRALSALGVAPSRLTWQGPQHGAFLHYRDPAEAQQAIACLQGFRLGANTVRVVLARQQRASDLVGSHTAEPLPDHQPAIAGP", "length": 380, "header": "sp|Q2KI24-1|MTHSD_BOVIN Isoform 1 of Methenyltetrahydrofolate synthase domain-containing protein OS=Bos taurus OX=9913 GN=MTHFSD PE=2 SV=1 CANONICAL=Q2KI24-1" }, "isoforms": [ { "isoform_ac": "A0A3Q1LKN7-1", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1LKN7/entry", "sequence": { "sequence": "MESQNLADFPRPVHHRIPNFKGSYLACQNIRDLEVFARTQELKVDPDKPLEGVRLLALQSKKTLLVPTPRLRTGLFNKITPPPGATKDILRKCATSQGVRNYSTPVGLDSKVLVDLVVVGSVAVSEKGWRIGKGEGYADLEYAMMVSMGAVSQGTPVVTIVHDCQVVDIPEALLEDHDLTVDYILTPTRVITTGCERPKPAGIAWSKISCEMLGKMPILRSLRHQEEQAGKDVTLRDGPRSPPGATRSPRDLAPPELGSVPLSSVQIGNLPRDARVSELKRALSALGVAPSRLTWQGPQHGAFLHYRDPAEAQQAIACLQGFRLGANTVRVVLARQQRASDLVGSHTAEPLPDHQPAIAGP", "length": 361, "header": "tr|A0A3Q1LKN7-1|MTHSD_BOVIN Computationally mapped isoform of Methenyltetrahydrofolate synthase domain-containing protein OS=Bos taurus OX=9913 GN=MTHFSD PE=2 SV=1 CANONICAL=Q2KI24-1" }, "locus": { "chromosome": "18", "start_pos": 12370285, "end_pos": 12356588, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000067145.2", "url": "https://www.ensembl.org/id/ENSBTAT00000067145.2" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000057280.1", "url": "https://www.ensembl.org/id/ENSBTAP00000057280.1" } ] } }, { "isoform_ac": "A0A3Q1MHY5-1", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1MHY5/entry", "sequence": { "sequence": "MEPRAAWKQHGKQVLVARWNGNKDLRRRLPSARTALGARGVSKQDIREQIWDYMESQNLADFPRPVHHRIPNFKGSYLACQNIRDLEVFARTQELKVDPDKPLEGVRLLALQSKKTLLVPTPRLRTGLFNKITPPPGATKDILRKCATSQGVRNYSTPVGLDSKVLVDLVVVGSVAVSEKGWRIGKGEGYADLEYAMMVSMGAVSQGTPVVTIVHDCQVVDIPEALLEDHDLTVDYILTPTRVITTGCERPKPAGIAWSKISCEMLGKMPILRSLRHQEEQAGKDVTLRDGPRSPPGATRSPRDLAPPELGSVPLSSVQIGNLPRDARVSELKRALSALGVAPSRLTWQGPQHGAFLHYRDPAEAQQAIACLQGFRLGANTVRVVLARQQRASDLVGSHTAEPLPDHQPAIAGP", "length": 414, "header": "tr|A0A3Q1MHY5-1|MTHSD_BOVIN Computationally mapped isoform of Methenyltetrahydrofolate synthase domain-containing protein OS=Bos taurus OX=9913 GN=MTHFSD PE=2 SV=3 CANONICAL=Q2KI24-1" }, "locus": { "chromosome": "18", "start_pos": 12373829, "end_pos": 12356588, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000084028.3", "url": "https://www.ensembl.org/id/ENSBTAT00000084028.3" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000070312.3", "url": "https://www.ensembl.org/id/ENSBTAP00000070312.3" } ] } }, { "isoform_ac": "A0AAF6ZB28-1", "url": "https://www.uniprot.org/uniprotkb/A0AAF6ZB28/entry", "sequence": { "sequence": "MREAERSHQASAARPPCPPVQTSAQARGVRAPVTSLRAGLRRGRRRALTASPWSRGRDIREQIWDYMESQNLADFPRPVHHRIPNFKGASRAAEHFPRLQAFKMARTIKVNPDAPQKNARFFVLESKKTLLVPTPRLRTGLFNKITPPPGATKDILRKCATSQGVRNYSTPVGLDSKVLVDLVVVGSVAVSEKGWRIGKGEGYADLEYAMMVSMGAVSQGTPVVTIVHDCQVVDIPEALLEDHDLTVDYILTPTRVITTGCERPKPAGIAWSKISCEMLGKMPILRSLRHQEEQAGKDVTLRDGPRSPPGATRSPRDLAPPELGSVPLSSVQIGNLPRDARVSELKRALSALGVAPSRLTWQGPQHGAFLHYRDPAEAQQAIACLQGFRLGANTVRVVLARQQRASDLVGSHTAEPLPDHQPAIAGP", "length": 427, "header": "tr|A0AAF6ZB28-1|A0AAF6ZB28_BOVIN Computationally mapped isoform of Methenyltetrahydrofolate synthase domain-containing protein OS=Bos taurus OX=9913 GN=MTHFSD PE=4 SV=1 CANONICAL=Q2KI24-1" }, "locus": { "chromosome": "18", "start_pos": 12373984, "end_pos": 12356588, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000032564.5", "url": "https://www.ensembl.org/id/ENSBTAT00000032564.5" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000032495.4", "url": "https://www.ensembl.org/id/ENSBTAP00000032495.4" } ] } }, { "isoform_ac": "Q2KI24-1", "url": "https://www.uniprot.org/uniprotkb/Q2KI24/entry#Q2KI24-1", "sequence": { "sequence": "MEPRAGVSKQDIREQIWDYMESQNLADFPRPVHHRIPNFKGASRAAEHFPRLQAFKMARTIKVNPDAPQKNARFFVLESKKTLLVPTPRLRTGLFNKITPPPGATKDILRKCATSQGVRNYSTPVGLDSKVLVDLVVVGSVAVSEKGWRIGKGEGYADLEYAMMVSMGAVSQGTPVVTIVHDCQVVDIPEALLEDHDLTVDYILTPTRVITTGCERPKPAGIAWSKISCEMLGKMPILRSLRHQEEQAGKDVTLRDGPRSPPGATRSPRDLAPPELGSVPLSSVQIGNLPRDARVSELKRALSALGVAPSRLTWQGPQHGAFLHYRDPAEAQQAIACLQGFRLGANTVRVVLARQQRASDLVGSHTAEPLPDHQPAIAGP", "length": 380, "header": "sp|Q2KI24-1|MTHSD_BOVIN Isoform 1 of Methenyltetrahydrofolate synthase domain-containing protein OS=Bos taurus OX=9913 GN=MTHFSD PE=2 SV=1 CANONICAL=Q2KI24-1" }, "locus": {} } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [ { "id": "bta:509897", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?bta:509897", "resource": "KEGG Pathway" } ], "orthologs": [ { "uniprot_canonical_ac": "A0A8V0XX30-1", "protein_name": "Methenyltetrahydrofolate synthase domain-containing protein", "gene_name": "MTHFSD", "tax_id": 9031, "organism": "Gallus gallus", "sequence": { "sequence": "MQEGVRLRAGERGAGRRAGRSGDVTGGRPLGVREGAGRHGRVPQHELCPSSGASKGDIREKVWDYLEASGLAEFPRPVHHRIPNFKGAPHAATRLLGLEEFKAANTVKINPDAPQKNARFLTLEARKTLLVPTPRLRSGLFNKIVPPPGATKETLRICATSQGIKEYSVPVGLDGKARVDLVVVGSVAVSEKGWRIGKGEGYADMEYAMMVSMGAVTEDTPVITIVHDCQVVDIAEELLGDHDLTIDYILTPTRTIKTNCKRPKPHGILWHKVSYEMLGKIPILKSLRYKEKQAGKDVTLQDEQPDLANASKSAALNGKAMDGNTRPQASMGSAQAGQQYVESDSLSPRLEGSGTVTTVYVGNIPPNLRVSELKCALREFRAAPLRVSWQGAQHRAFLDYKDKATAESAVSSLKGLSLGGNTLRVELAKNQRNKGQVEINSQT", "length": 443 }, "evidence": [ { "id": "Q2KI24", "url": "https://omabrowser.org/oma/group/Q2KI24/", "database": "OMA" } ], "glygen_name": "Chicken", "common_name": "Chicken" }, { "uniprot_canonical_ac": "A0ABK0LN54-1", "protein_name": "Methenyltetrahydrofolate synthase domain-containing protein", "gene_name": "Mthfsd", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MRLTSSVRRQALREASLGDVLVMEARAGDVSKQSIRERIWDYMESHNIADFPRPVHHRIPNFKGASRAAEHFPHLHAFSAARTIKVNPDAPQRNARFLVLESRKTLLVPTPRLRTGLFNKIIPPPGATKDILRKCATSQGVRNFSVPVGLDSNVLVDLVVVGSVAVSEKGWRIGKGEGYADLEYAMMVSMGAVHEGTLVVTIVHDCQVVDIPEALLEDHDLTVDYILTPTRVIATGCARPKPTGILWSKVSCEMLTKIPVLRSLREREKRAGTDVTLQAEPGNTQQPAPSTVRRPQDRPQSQPAPSTVRRPQDRPQSQAGFRGRSHSSLEGTDTHLAATVCLGNLPYSARVRELKRALQELGAVPLRLTWQGPQHRAILHYTDSAAAQQAASLLQGLRLGDNALRVSLGQQRDT", "length": 414 }, "evidence": [ { "id": "Q2KI24", "url": "https://omabrowser.org/oma/group/Q2KI24/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "Q0P464-1", "protein_name": "Methenyltetrahydrofolate synthase domain-containing protein", "gene_name": "mthfsd", "tax_id": 7955, "organism": "Danio rerio", "sequence": { "sequence": "MEPVIKINQGETKWDVRHKVWNYIEVKNLANFPRPVHNRIPNFKGALEACNKVAQLEIFIESAVVKVDPDKPMEGVRLAALKARKSLLVPTPRLRFGLFNRITPPKGATKETLRVCSTSQGIKEFSVPVGLDDKVQVDLVVVGSVAVSEKGYRIGKGEGFADMEYAMMACMGSVTESTWVITVVHDCQVMDIPEELIERHDLMVDFIITATRVIKTECKHPKPQGIIWSMLHKEELKKIPILKKLRTLEQEAGKDVALKLIHAGEDEYRKSKELQWQSHPKADLEFKCLASNSDRCSGFEPKFPTTTVYLSDIPPALRVSELKGLLREQEVVPLQIRWQGAKRKAFLLYADFTGAERATAILQKLFINGHTIQAKCVSSQKM", "length": 382 }, "evidence": [ { "id": "Q2KI24", "url": "https://omabrowser.org/oma/group/Q2KI24/", "database": "OMA" } ], "glygen_name": "Zebrafish", "common_name": "Zebrafish" }, { "uniprot_canonical_ac": "Q3URQ7-1", "protein_name": "Methenyltetrahydrofolate synthase domain-containing protein", "gene_name": "Mthfsd", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "METQEGVSKQSIRERIWDYMESHDIADFPRPVHHRIPNFKGAAQAAGHLPHLQAFHVARTIKVNPDAPQRNARFLVLESKKTLLVPTPRLRTGLFNKITPPPGATKDILRKCATSQGVRNFSVPVGLDSSVLVDLVVVGSVAVSEKGWRIGKGEGYADLEYAMMVSMGAVHKGTPVVTIVHDCQVVDIPEALVEDHDLTVDYILTPTRVITTGCARPKPTGIMWSKVSCEMLTKIPVLRNLREREKQAGKDVTLRDEPGSQQPAPGPIRRPQDRPQTGSRGGSRSPLQGADTQLAATVCVGNLPFTTRVRELKRVLQELGVVPLRLTWQGPQHRAVLHYTDSAAAQQAASLLQGLRLGANALRVSLGQQRDM", "length": 372 }, "evidence": [ { "id": "Q2KI24", "url": "https://omabrowser.org/oma/group/Q2KI24/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" } ], "go_annotation": { "categories": [ { "name": "Molecular Function", "total": 1, "go_terms": [ { "name": "RNA binding", "id": "GO:0003723", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003723", "evidence": [ { "database": "UniProtKB", "id": "Q2KI24", "url": "https://www.uniprot.org/uniprotkb/Q2KI24" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 1, "go_terms": [ { "name": "cytoplasm", "id": "GO:0005737", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005737", "evidence": [ { "database": "UniProtKB", "id": "Q2KI24", "url": "https://www.uniprot.org/uniprotkb/Q2KI24" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 120, "end_pos": 122, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [ { "pdb_id": "AF-Q2KI24-F1", "pdb_chain": "global", "start_pos": 1, "end_pos": 380, "overlap": "1.0", "method": "AlphaFold", "type": "alphafold", "resolution": -1.0, "url": "https://data.glygen.org/ln2downloads/pdb/current/AF-Q2KI24-F1.pdb", "url_external": "https://alphafold.ebi.ac.uk/entry/Q2KI24" } ], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "Q2KI24", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q2KI24" }, { "id": "PRU00176", "database": "PROSITE", "url": "https://prosite.expasy.org/PRU00176" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "RRM", "eco_id": "ECO_0000255", "start_pos": 282, "end_pos": 355, "start_aa": "Ser", "end_aa": "Gln", "glycosite_overlap": [] } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" }, { "name": "homologset.oma", "label": "OMA Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 120, "end_pos": 122 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ], "tool_support": { "graph_view": "yes" } }, { "uniprot_canonical_ac": "Q3SX00-1", "uniprot_ac": "Q3SX00", "uniprot_id": "ANR46_BOVIN", "mass": { "chemical_mass": 25330.0, "monoisotopic_mass": 25330.0 }, "refseq": { "ac": "NP_001029791", "name": "ankyrin repeat domain-containing protein 46", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001029791" }, "gene_names": [ { "name": "ANKRD46", "type": "recommended", "evidence": [ { "id": "Q3SX00", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q3SX00" } ] }, { "name": "ANKRD46", "type": "synonym", "evidence": [ { "id": "NP_001029791", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001029791" } ] } ], "protein_names": [ { "name": "Ankyrin repeat domain-containing protein 46", "type": "recommended", "evidence": [ { "id": "Q3SX00", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q3SX00/entry#names_and_taxonomy" } ] }, { "name": "ankyrin repeat domain-containing protein 46", "type": "synonym", "evidence": [ { "id": "NP_001029791", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001029791" } ] } ], "function": [], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Bos taurus", "taxid": 9913, "evidence": [ { "database": "UniProtKB", "id": "Q3SX00", "url": "https://www.uniprot.org/uniprotkb/Q3SX00" } ], "common_name": "Bovine", "glygen_name": "Bovine", "reference_species": "Bos taurus [9913]" } ], "gene": [ { "name": "ANKRD46", "url": "https://www.uniprot.org/uniprotkb/Q3SX00", "locus": { "chromosome": "14", "start_pos": 63868201, "end_pos": 63800486, "strand": "-", "evidence": [ { "database": "Ensembl Gene", "id": "ENSBTAG00000001254", "url": "https://www.ensembl.org/id/ENSBTAG00000001254" } ] } } ], "crossref": [ { "id": "Q3SX00", "url": "https://alphafold.ebi.ac.uk/entry/Q3SX00", "database": "AlphaFoldDB", "categories": [] }, { "id": "ENSBTAG00000001254", "url": "https://bgee.org/?page=gene&gene_id=ENSBTAG00000001254", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "534898", "url": "https://www.ncbi.nlm.nih.gov/gene/534898", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR002110", "url": "https://www.ebi.ac.uk/interpro/entry/IPR002110", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR036770", "url": "https://www.ebi.ac.uk/interpro/entry/IPR036770", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR039323", "url": "https://www.ebi.ac.uk/interpro/entry/IPR039323", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "bta:534898", "url": "https://www.genome.jp/dbget-bin/www_bget?bta:534898", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "EYQGNTA", "url": "https://omabrowser.org/oma/group/EYQGNTA/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "A0A3Q1LM68", "url": "https://www.orthodb.org/?gene=A0A3Q1LM68", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A3Q1MFS7", "url": "https://www.orthodb.org/?gene=A0A3Q1MFS7", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "Q3SX00", "url": "https://www.orthodb.org/?gene=Q3SX00", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR22677", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR22677", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR22677:SF4", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR22677:SF4", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR24171", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR24171", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR24171:SF9", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR24171:SF9", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF12796", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF12796", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "NP_001029791", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001029791", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A3Q1LM68", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1LM68", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A3Q1LM68-1", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1LM68-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A3Q1MFS7", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1MFS7", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A3Q1MFS7-1", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1MFS7-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0AAA9T296", "url": "https://www.uniprot.org/uniprotkb/A0AAA9T296", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0AAA9T296-1", "url": "https://www.uniprot.org/uniprotkb/A0AAA9T296-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0AAA9TR47", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TR47", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0AAA9TR47-1", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TR47-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "Q3SX00", "url": "https://www.uniprot.org/uniprotkb/Q3SX00", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "Q3SX00-1", "url": "https://www.uniprot.org/uniprotkb/Q3SX00-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MSYVFVNDSSQTNVPLLQACIDGDFNYSKRLLESGFDPNIRDSRGRTGLHLAAARGNVDICQLLHKFGADLLATDYQGNTALHLCGHVDTIQFLVSNGLKIDICNHQGATPLVLAKRRGVNKDVIRLLESLEEQEVKGFNRGTHSKLETMQTAESESAMESHSLLNPNLQQGEGVLSSFRTTWQEFVEDLGFWRVLLLIFVIALLSLGIAYYVSGVLPFVENQPELVH", "length": 228, "header": "sp|Q3SX00-1|ANR46_BOVIN Isoform 1 of Ankyrin repeat domain-containing protein 46 OS=Bos taurus OX=9913 GN=ANKRD46 PE=2 SV=1 CANONICAL=Q3SX00-1" }, "isoforms": [ { "isoform_ac": "A0A3Q1LM68-1", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1LM68/entry", "sequence": { "sequence": "MSYVFVNDSSQTNVPLLQACIDGDFNYSKRLLESGFDPNIRDSRGRTGLHLAAARGNVDICQLLHKFGADLLATDYQGNTALHLCGHVDTIQFLVSNGLKIDICNHQGATPLVLAKRRGVNKDVIRLLESLEEQEVKGFNRGTHSKLETMQTAESESAMESHSLLNPNLQQGEGVLSSFRTTWQEFVEDLGFWRVLLLIFVIALLSLGIAYYA", "length": 213, "header": "tr|A0A3Q1LM68-1|ANR46_BOVIN Computationally mapped isoform of Ankyrin repeat domain-containing protein 46 OS=Bos taurus OX=9913 GN=ANKRD46 PE=2 SV=1 CANONICAL=Q3SX00-1" }, "locus": { "chromosome": "14", "start_pos": 63867197, "end_pos": 63831621, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000082876.3", "url": "https://www.ensembl.org/id/ENSBTAT00000082876.3" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000057940.1", "url": "https://www.ensembl.org/id/ENSBTAP00000057940.1" } ] } }, { "isoform_ac": "A0A3Q1MFS7-1", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1MFS7/entry", "sequence": { "sequence": "MSYVFVNDSSQTNVPLLQACIDGDFNYSKRLLESGFDPNIRDSRGRTGLHLAAARGNVDICQLLHKFGADLLATDYQGNTALHLCGHVDTIQFLVSNGLKIDICNHQGATPLVLAKRRGVNKDVIRLLESLEEQEVKGFNRGTHSKLETMQTAESESAMESHSLLNPNLQQGEGVLSSFRTTWQEFVEDLGFWRVLLLIFVIALLSLGIAYYD", "length": 213, "header": "tr|A0A3Q1MFS7-1|ANR46_BOVIN Computationally mapped isoform of Ankyrin repeat domain-containing protein 46 OS=Bos taurus OX=9913 GN=ANKRD46 PE=2 SV=1 CANONICAL=Q3SX00-1" }, "locus": { "chromosome": "14", "start_pos": 63841366, "end_pos": 63831621, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000074180.3", "url": "https://www.ensembl.org/id/ENSBTAT00000074180.3" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000067822.1", "url": "https://www.ensembl.org/id/ENSBTAP00000067822.1" } ] } }, { "isoform_ac": "A0AAA9T296-1", "url": "https://www.uniprot.org/uniprotkb/A0AAA9T296/entry", "sequence": { "sequence": "MSYVFVNDSSQTNVPLLQACIDGDFNYSKRLLESGFDPNIRDSRGRTGLHLAAARGNVDICQLLHKFGADLLATDYQGNTALHLCGHVDTIQFLVSNGLKIDICNHQGATPLVLAKRRGVNKDVIRLLESLEEQEVKGFNRGTHSKLETMQTAESESAMESHSLLNPNLQQGEGVLSSFRTTWQEFVEDLGFWRVLLLIFVIALLSLGIAYYRPAVWCLQRCIHLQMNQSTPSPVTIERKVVNSLSFR", "length": 248, "header": "tr|A0AAA9T296-1|ANR46_BOVIN Computationally mapped isoform of Ankyrin repeat domain-containing protein 46 OS=Bos taurus OX=9913 GN=ANKRD46 PE=2 SV=1 CANONICAL=Q3SX00-1" }, "locus": { "chromosome": "14", "start_pos": 63860150, "end_pos": 63831621, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000099150.2", "url": "https://www.ensembl.org/id/ENSBTAT00000099150.2" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000092920.1", "url": "https://www.ensembl.org/id/ENSBTAP00000092920.1" } ] } }, { "isoform_ac": "A0AAA9TR47-1", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TR47/entry", "sequence": { "sequence": "MSYVFVNDSSQTNVPLLQACIDGDFNYSKRLLESGFDPNIRDSRGRTGLHLAAARGNVDICQLLHKFGADLLATDYQGNTALHLCGHVDTIQFLVSNGLKIDICAMESHSLLNPNLQQGEGVLSSFRTTWQEFVEDLGFWRVLLLIFVIALLSLGIAYYVSGVLPFVENQPELVH", "length": 175, "header": "tr|A0AAA9TR47-1|ANR46_BOVIN Computationally mapped isoform of Ankyrin repeat domain-containing protein 46 OS=Bos taurus OX=9913 GN=ANKRD46 PE=2 SV=1 CANONICAL=Q3SX00-1" }, "locus": {} }, { "isoform_ac": "Q3SX00-1", "url": "https://www.uniprot.org/uniprotkb/Q3SX00/entry#Q3SX00-1", "sequence": { "sequence": "MSYVFVNDSSQTNVPLLQACIDGDFNYSKRLLESGFDPNIRDSRGRTGLHLAAARGNVDICQLLHKFGADLLATDYQGNTALHLCGHVDTIQFLVSNGLKIDICNHQGATPLVLAKRRGVNKDVIRLLESLEEQEVKGFNRGTHSKLETMQTAESESAMESHSLLNPNLQQGEGVLSSFRTTWQEFVEDLGFWRVLLLIFVIALLSLGIAYYVSGVLPFVENQPELVH", "length": 228, "header": "sp|Q3SX00-1|ANR46_BOVIN Isoform 1 of Ankyrin repeat domain-containing protein 46 OS=Bos taurus OX=9913 GN=ANKRD46 PE=2 SV=1 CANONICAL=Q3SX00-1" }, "locus": { "chromosome": "14", "start_pos": 63839902, "end_pos": 63831621, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000093933.2", "url": "https://www.ensembl.org/id/ENSBTAT00000093933.2" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000098922.2", "url": "https://www.ensembl.org/id/ENSBTAP00000098922.2" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [ { "id": "bta:534898", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?bta:534898", "resource": "KEGG Pathway" } ], "orthologs": [ { "uniprot_canonical_ac": "A0A1D5PRA5-1", "protein_name": "Ankyrin repeat domain 46", "gene_name": "ANKRD46", "tax_id": 9031, "organism": "Gallus gallus", "sequence": { "sequence": "MSYVFVNDSSQTNVPLLQACIDGDFNYSKRLLESGFDPNIRDSRGRTGLHLAAARGNVDICQLLHKFGADLLATDYQGNTALHLCGHVDTIQFLVSNGLKIDICNHQGATPLVLAKRRGVNKDVIRLLESLEEQEVKGFNRGAHSKLETMQTAESESAMESHSLLNPNLQQGEGVLSSFRTTWQEFVEDLGFWRVLLLIIVIALLSLGIAYYVSGVLPFVENQPELVH", "length": 228 }, "evidence": [ { "id": "Q3SX00", "url": "https://omabrowser.org/oma/group/Q3SX00/", "database": "OMA" } ], "glygen_name": "Chicken", "common_name": "Chicken" }, { "uniprot_canonical_ac": "F2Z556-1", "protein_name": "Ankyrin repeat domain 46", "gene_name": "ANKRD46", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MSYVFVNDSSQTNVPLLQACIDGDFNYSKRLLESGFDPNIRDSRGRTGLHLAAARGNVDICQLLHKFGADLLATDYQGNTALHLCGHVDTIQFLVSNGLKIDICNHQGATPLVLAKRRGVNKDVIRLLESLEEQEVKGFNRGTHSKLETMQTAESESAMESHSLLNPNLQQGEGVLSSFRTTWQEFVEDLGFWRVLLLIFVIALLSLGIAYYVSGVLPFVENQPELVH", "length": 228 }, "evidence": [ { "id": "Q3SX00", "url": "https://omabrowser.org/oma/group/Q3SX00/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "Q6TNT2-1", "protein_name": "Ankyrin repeat domain-containing protein 46", "gene_name": "ankrd46", "tax_id": 7955, "organism": "Danio rerio", "sequence": { "sequence": "MSYVFINDSSQTSVPLLQACIDGDLSFARRLLETGCDPNIRDHRGRTGLHLAAARGNVDICRFLHKFGADLLATDYQGNTALHLCGHVDTIQFLVSNGLKIDICNHNGSTPLVLAKRRGVNKDAIRLLEGLEEQEVKGFNRGAHSKLEAMQMAESESAMESHSLLNPNLQNSEGVLSSFRSTWQEFVEDLGFWRVLLLLVVIALLSLGIAYYVSGVLPFSASQLELVH", "length": 228 }, "evidence": [ { "id": "Q3SX00", "url": "https://omabrowser.org/oma/group/Q3SX00/", "database": "OMA" } ], "glygen_name": "Zebrafish", "common_name": "Zebrafish" }, { "uniprot_canonical_ac": "Q76K24-1", "protein_name": "Ankyrin repeat domain-containing protein 46", "gene_name": "Ankrd46", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MSYVFVNDSSQTNVPLLQACIDGDFTYSKRLLESGFDPNIRDSRGRTGLHLAAARGNVDICQLLHKFGADPLATDYQGNTALHLCGHVDTIQFLVSNGLKIDICNHQGATPLVLAKRRGVNKDVIRLLESLEEQEVKGFNRGTHSKLETMQTAESESAMESHSLLNPNLQQGEGVLSSFRTTWQEFVEDLGFWRVLLLILVIALLSLGIAYYVSGVLPFVDNQPGLVH", "length": 228 }, "evidence": [ { "id": "Q3SX00", "url": "https://omabrowser.org/oma/group/Q3SX00/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "Q86W74-2", "protein_name": "Ankyrin repeat domain-containing protein 46", "gene_name": "ANKRD46", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MSYVFVNDSSQTNVPLLQACIDGDFNYSKRLLESGFDPNIRDSRGRTGLHLAAARGNVDICQLLHKFGADLLATDYQGNTALHLCGHVDTIQFLVSNGLKIDICNHQGATPLVLAKRRGVNKDVIRLLESLEEQEVKGFNRGTHSKLETMQTAESESAMESHSLLNPNLQQGEGVLSSFRTTWQEFVEDLGFWRVLLLIFVIALLSLGIAYYVSGVLPFVENQPELVH", "length": 228 }, "evidence": [ { "id": "Q3SX00", "url": "https://omabrowser.org/oma/group/Q3SX00/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "Q8BTZ5-1", "protein_name": "Ankyrin repeat domain-containing protein 46", "gene_name": "Ankrd46", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MSYVFVNDSSQTNVPLLQACIDGDFTYSKRLLESGFDPNIRDSRGRTGLHLAAARGNVDICQLLHKFGADPLATDYQGNTALHLCGHVDTIQFLVSNGLKIDICNHQGATPLVLAKRRGVNKDVIRLLESLEEQEVKGFNRGAHSKLETMQTAESESAMESHSLLNPNLQQGEGVLSSFRTTWQEFVEDLGFWRVLLLILVIALLSLGIAYYVSGVLPFVDNQPELVH", "length": 228 }, "evidence": [ { "id": "Q3SX00", "url": "https://omabrowser.org/oma/group/Q3SX00/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" } ], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 1, "go_terms": [ { "name": "membrane", "id": "GO:0016020", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016020", "evidence": [ { "database": "UniProtKB", "id": "Q3SX00", "url": "https://www.uniprot.org/uniprotkb/Q3SX00" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 26, "end_pos": 28, "annotation": "n_glycosylation_sequon" }, { "start_pos": 7, "end_pos": 9, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [ { "pdb_id": "AF-Q3SX00-F1", "pdb_chain": "global", "start_pos": 1, "end_pos": 228, "overlap": "1.0", "method": "AlphaFold", "type": "alphafold", "resolution": -1.0, "url": "https://data.glygen.org/ln2downloads/pdb/current/AF-Q3SX00-F1.pdb", "url_external": "https://alphafold.ebi.ac.uk/entry/Q3SX00" } ], "lectin_list": [], "domain_list": [], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" }, { "name": "homologset.oma", "label": "OMA Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 26, "end_pos": 28 }, { "start_pos": 7, "end_pos": 9 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": 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"uniprot_canonical_ac": "Q32LL6-1", "uniprot_ac": "Q32LL6", "uniprot_id": "MORN5_BOVIN", "mass": { "chemical_mass": 20016.0, "monoisotopic_mass": 20016.0 }, "refseq": { "ac": "NP_001069778", "name": "MORN repeat-containing protein 5", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001069778" }, "gene_names": [ { "name": "MORN5", "type": "recommended", "evidence": [ { "id": "Q32LL6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q32LL6" } ] }, { "name": "C11H9orf18", "type": "synonym", "evidence": [ { "id": "NP_001069778", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001069778" } ] }, { "name": "C9orf18", "type": "synonym", "evidence": [ { "id": "NP_001069778", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001069778" } ] }, { "name": "MORN5", "type": "synonym", "evidence": [ { "id": "NP_001069778", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001069778" } ] } ], "protein_names": [ { "name": "MORN repeat-containing protein 5", "type": "recommended", "evidence": [ { "id": "Q32LL6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q32LL6/entry#names_and_taxonomy" } ] }, { "name": "MORN repeat-containing protein 5", "type": "synonym", "evidence": [ { "id": "NP_001069778", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001069778" } ] } ], "function": [], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Bos taurus", "taxid": 9913, "evidence": [ { "database": "UniProtKB", "id": "Q32LL6", "url": "https://www.uniprot.org/uniprotkb/Q32LL6" } ], "common_name": "Bovine", "glygen_name": "Bovine", "reference_species": "Bos taurus [9913]" } ], "gene": [ { "name": "MORN5", "url": "https://www.uniprot.org/uniprotkb/Q32LL6", "locus": { "chromosome": "11", "start_pos": 93081438, "end_pos": 93032967, "strand": "-", "evidence": [ { "database": "Ensembl Gene", "id": "ENSBTAG00000004296", "url": "https://www.ensembl.org/id/ENSBTAG00000004296" } ] } } ], "crossref": [ { "id": "Q32LL6", "url": "https://alphafold.ebi.ac.uk/entry/Q32LL6", "database": "AlphaFoldDB", "categories": [] }, { "id": "ENSBTAG00000004296", "url": "https://bgee.org/?page=gene&gene_id=ENSBTAG00000004296", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "614076", "url": "https://www.ncbi.nlm.nih.gov/gene/614076", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "9FQR", "url": "https://www.ncbi.nlm.nih.gov/Structure/icn3d/?mmdbid=9FQR&bu=0", "database": "iCn3D", "categories": [ "3D Structure" ] }, { "id": "IPR003409", "url": "https://www.ebi.ac.uk/interpro/entry/IPR003409", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR042814", "url": "https://www.ebi.ac.uk/interpro/entry/IPR042814", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "bta:614076", "url": "https://www.genome.jp/dbget-bin/www_bget?bta:614076", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "A0A3Q1LMN5", "url": "https://www.orthodb.org/?gene=A0A3Q1LMN5", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A452DHZ9", "url": "https://www.orthodb.org/?gene=A0A452DHZ9", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "Q32LL6", "url": "https://www.orthodb.org/?gene=Q32LL6", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR46437", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR46437", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR46437:SF1", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR46437:SF1", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "pdb_00009fqr", "url": "https://www.rcsb.org/structure/pdb_00009fqr", "database": "PDB", "categories": [ "3D Structure" ] }, { "id": "9FQR", "url": "https://www.rcsb.org/structure/9FQR", "database": "PDB", "categories": [ "3D Structure" ] }, { "id": "PF02493", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF02493", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "NP_001069778", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001069778", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A3Q1LMN5", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1LMN5", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A3Q1LMN5-1", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1LMN5-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A452DHZ9", "url": "https://www.uniprot.org/uniprotkb/A0A452DHZ9", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A452DHZ9-1", "url": "https://www.uniprot.org/uniprotkb/A0A452DHZ9-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0AAA9S4I0", "url": "https://www.uniprot.org/uniprotkb/A0AAA9S4I0", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0AAA9S4I0-1", "url": "https://www.uniprot.org/uniprotkb/A0AAA9S4I0-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0AAA9STW4", "url": "https://www.uniprot.org/uniprotkb/A0AAA9STW4", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0AAA9STW4-1", "url": "https://www.uniprot.org/uniprotkb/A0AAA9STW4-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0AAA9T952", "url": "https://www.uniprot.org/uniprotkb/A0AAA9T952", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0AAA9T952-1", "url": "https://www.uniprot.org/uniprotkb/A0AAA9T952-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0AAA9TAL1", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TAL1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0AAA9TAL1-1", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TAL1-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0AAA9TTV5", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TTV5", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0AAA9TTV5-1", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TTV5-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0ABI0NPD9", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NPD9", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0ABI0NPD9-1", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NPD9-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0ABI0P6H7", "url": "https://www.uniprot.org/uniprotkb/A0ABI0P6H7", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0ABI0P6H7-1", "url": "https://www.uniprot.org/uniprotkb/A0ABI0P6H7-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "Q32LL6", "url": "https://www.uniprot.org/uniprotkb/Q32LL6", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "Q32LL6-1", "url": "https://www.uniprot.org/uniprotkb/Q32LL6-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MEYTGSQYIGEFVDGRMEGDAEYILPTETKYIGEMKDGMFHGQGTLYFPNGSRFDAVWEKGLVVKGTYTFSDGLQYDTENWHYCDSYDRRFYTEICYGLKPAGISQLTNMDPPRKIPPGCYDCGDGFYNPNTRIVKDYNYRFLRNADDDEHEWIVRTCRKGWDETMGPEPKS", "length": 172, "header": "sp|Q32LL6-1|MORN5_BOVIN Isoform 1 of MORN repeat-containing protein 5 OS=Bos taurus OX=9913 GN=MORN5 PE=1 SV=1 CANONICAL=Q32LL6-1" }, "isoforms": [ { "isoform_ac": "A0A3Q1LMN5-1", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1LMN5/entry", "sequence": { "sequence": "MVRQDALSLRCPKDWTLETGAMEYTGSQYIGEFVDGRMEGDAEYILPTETKYIGEMKDGMFHGQGTLYFPNGSRFDAVWEKGLVVKGTYTFSDGLQYDTENWHYCDSYDRRFYTEICYGLKPAGISQLTNMDPPRKIPPGCYDCGDGFYNPNTRIVKDYNYRFLRNAVLCPLYCSKPGQRTGVFQCHQ", "length": 188, "header": "tr|A0A3Q1LMN5-1|MORN5_BOVIN Computationally mapped isoform of MORN repeat-containing protein 5 OS=Bos taurus OX=9913 GN=MORN5 PE=1 SV=2 CANONICAL=Q32LL6-1" }, "locus": { "chromosome": "11", "start_pos": 93067677, "end_pos": 93046946, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000080188.2", "url": "https://www.ensembl.org/id/ENSBTAT00000080188.2" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000061156.2", "url": "https://www.ensembl.org/id/ENSBTAP00000061156.2" } ] } }, { "isoform_ac": "A0A452DHZ9-1", "url": "https://www.uniprot.org/uniprotkb/A0A452DHZ9/entry", "sequence": { "sequence": "MEYTGSQYIGEFVDGRMEGDAEYILPTETKYIGEMKDGMFHGQGTLYFPNGSRFDAVWEKGLVVKVSLNSPIWTHLERSLQAVTTAETASITRTRG", "length": 96, "header": "tr|A0A452DHZ9-1|MORN5_BOVIN Computationally mapped isoform of MORN repeat-containing protein 5 OS=Bos taurus OX=9913 GN=MORN5 PE=1 SV=3 CANONICAL=Q32LL6-1" }, "locus": { "chromosome": "11", "start_pos": 93055939, "end_pos": 93047009, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000005632.6", "url": "https://www.ensembl.org/id/ENSBTAT00000005632.6" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000005632.6", "url": "https://www.ensembl.org/id/ENSBTAP00000005632.6" } ] } }, { "isoform_ac": "A0AAA9S4I0-1", "url": "https://www.uniprot.org/uniprotkb/A0AAA9S4I0/entry", "sequence": { "sequence": "MMAVAATPRRCPLPRLPRLLELPFRTRRPPSVCAGAAAAARRRTALPNHKPRSLRKAGKFPVPRGGASSRPRPSLLVVMVRQDALSLRCPKDWTLETGAMEYTGSQYIGEFVDGRMEGDAEYILPTETKYIGEMKDGMFHGQGTLYFPNGSRFDAVWEKGLVVKGTYTFSDGLQYDTENWHYCDSYDRRFYTEICYGLKPAGISQLTNMDPPRKIPPGCYDCGDGFYNPNTRIVKDYNYRFLRNADPSAAAAAAKLLQSCPTLCNPIDSSPPGSPFPGILPARTLEWVASWR", "length": 292, "header": "tr|A0AAA9S4I0-1|MORN5_BOVIN Computationally mapped isoform of MORN repeat-containing protein 5 OS=Bos taurus OX=9913 GN=MORN5 PE=1 SV=1 CANONICAL=Q32LL6-1" }, "locus": { "chromosome": "11", "start_pos": 93062480, "end_pos": 93046712, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000128441.1", "url": "https://www.ensembl.org/id/ENSBTAT00000128441.1" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000077038.1", "url": "https://www.ensembl.org/id/ENSBTAP00000077038.1" } ] } }, { "isoform_ac": "A0AAA9STW4-1", "url": "https://www.uniprot.org/uniprotkb/A0AAA9STW4/entry", "sequence": { "sequence": "MVRQDALSLRCPKDWTLETGAMEYTGSQYIGEFVDGRMEGDAEYILPTETKYIGEMKDGMFHGQGTLYFPNGSRFDAVWEKGLVVKGTYTFSDGLQYDTENWHYCDSYDRRFYTEICYGLKPAGISQLTNMDPPRKIPPGCYDCGDGFYNPNTRIVKDYNYRFLRNAGSHLCRRGNDTQM", "length": 180, "header": "tr|A0AAA9STW4-1|MORN5_BOVIN Computationally mapped isoform of MORN repeat-containing protein 5 OS=Bos taurus OX=9913 GN=MORN5 PE=1 SV=1 CANONICAL=Q32LL6-1" }, "locus": { "chromosome": "11", "start_pos": 93073681, "end_pos": 93046946, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000098689.1", "url": "https://www.ensembl.org/id/ENSBTAT00000098689.1" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000086545.1", "url": "https://www.ensembl.org/id/ENSBTAP00000086545.1" } ] } }, { "isoform_ac": "A0AAA9T952-1", "url": "https://www.uniprot.org/uniprotkb/A0AAA9T952/entry", "sequence": { "sequence": "MVRQDALSLRCPKDWTLETGAMEYTGSQYIGEFVDGRMEGDAEYILPTETKYIGEMKDGMFHGQGTLYFPNGSRFDAVWEKGLVVKGTYTFSDGLQYDTENWHYCDSYDRRFYTEICYGLKPAGISQLTNMDPPRKIPPGCYDCGDGFYNPNTRIVKDYNYRFLRNAGVPGTRGNSAML", "length": 179, "header": "tr|A0AAA9T952-1|MORN5_BOVIN Computationally mapped isoform of MORN repeat-containing protein 5 OS=Bos taurus OX=9913 GN=MORN5 PE=1 SV=1 CANONICAL=Q32LL6-1" }, "locus": { "chromosome": "11", "start_pos": 93065170, "end_pos": 93046946, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000103052.1", "url": "https://www.ensembl.org/id/ENSBTAT00000103052.1" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000095228.1", "url": "https://www.ensembl.org/id/ENSBTAP00000095228.1" } ] } }, { "isoform_ac": "A0AAA9TAL1-1", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TAL1/entry", "sequence": { "sequence": "MGLPELTGVRPRVNLVYMLRALGWDGRSGAQGPLSASPAGPRPGKLQPCAPLAFFRTSLTSCTFRSSREGSSTIPGMMAVAATPRRCPLPRLPRLLELPFRTRRPPSVCAGAAAAARRRTALPNHKPRSLRKAGKFPVPRGGASSRPRPSLLVVMVRQDALSLRCPKDWTLETGAMEYTGSQYIGEFVDGRMEGDAEYILPTETKYIGEMKDGMFHGQGTLYFPNGSRFDAVWEKGLVVKGTYTFSDGLQYDTENWHYCDSYDRRFYTEICYGLKPAGISQLTNMDPPRKIPPGCYDCGDGFYNPNTRIVKDYNYRFLRNADDDEHEWIVRTCRKGWDETMGPEPKS", "length": 347, "header": "tr|A0AAA9TAL1-1|MORN5_BOVIN Computationally mapped isoform of MORN repeat-containing protein 5 OS=Bos taurus OX=9913 GN=MORN5 PE=1 SV=1 CANONICAL=Q32LL6-1" }, "locus": { "chromosome": "11", "start_pos": 93081312, "end_pos": 93046484, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000130951.2", "url": "https://www.ensembl.org/id/ENSBTAT00000130951.2" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000095032.1", "url": "https://www.ensembl.org/id/ENSBTAP00000095032.1" } ] } }, { "isoform_ac": "A0AAA9TTV5-1", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TTV5/entry", "sequence": { "sequence": "MMAVAATPRRCPLPRLPRLLELPFRTRRPPSVCAGAAAAARRRTALPNHKPRSLRKAGKFPVPRGGASSRPRPSLLVVMVRQDALSLRCPKDWTLETGAMEYTGSQYIGEFVDGRMEGDAEYILPTETKYIGEMKDGMFHGQGTLYFPNGSRFDAVWEKGLVVKGTYTFSDGLQYDTENWHYCDSYDRRFYTEICYGLKPAGISQLTNMDPPRKIPPGCYDCGDGFYNPNTRIVKDYNYRFLRNAGWIKFGVSWKPLRGSLCWWRTGHYPELTSPCWGLW", "length": 280, "header": "tr|A0AAA9TTV5-1|MORN5_BOVIN Computationally mapped isoform of MORN repeat-containing protein 5 OS=Bos taurus OX=9913 GN=MORN5 PE=1 SV=1 CANONICAL=Q32LL6-1" }, "locus": { "chromosome": "11", "start_pos": 93061210, "end_pos": 93046712, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000132594.1", "url": "https://www.ensembl.org/id/ENSBTAT00000132594.1" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000100811.1", "url": "https://www.ensembl.org/id/ENSBTAP00000100811.1" } ] } }, { "isoform_ac": "A0ABI0NPD9-1", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NPD9/entry", "sequence": { "sequence": "MEYTGSQYIGEFVDGRMEGDAEYILPTETKYIGEMKDGMFHGQGTLYFPNGSRFDAVWEKGLVVKGTYTFSDGLQYDTENWHYCDSYDRRFYTEICYGLKPAGISQLTNMDPPRKIPPGCYDCGDGFYNPNTRIVKDYNYRFLRNAGLPLKRLQLH", "length": 156, "header": "tr|A0ABI0NPD9-1|A0ABI0NPD9_BOVIN Computationally mapped isoform of MORN repeat-containing protein 5 OS=Bos taurus OX=9913 GN=MORN5 PE=4 SV=1 CANONICAL=Q32LL6-1" }, "locus": { "chromosome": "11", "start_pos": 93078940, "end_pos": 93047009, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000152517.1", "url": "https://www.ensembl.org/id/ENSBTAT00000152517.1" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000107766.1", "url": "https://www.ensembl.org/id/ENSBTAP00000107766.1" } ] } }, { "isoform_ac": "A0ABI0P6H7-1", "url": "https://www.uniprot.org/uniprotkb/A0ABI0P6H7/entry", "sequence": { "sequence": "MEGDAEYILPTETKYIGEMKDGMFHGQGTLYFPNGSRFDAVWEKGLVVKGTYTFSDGLQYDTENWHYCDSYDRRFYTEICYGLKPAGISQLTNMDPPRKIPPGCYDCGDGFYNPNTRIVKDYNYRFLRNADDDEHEWIVRTCRKGWDETMGPEPKS", "length": 156, "header": "tr|A0ABI0P6H7-1|A0ABI0P6H7_BOVIN Computationally mapped isoform of MORN repeat-containing protein 5 OS=Bos taurus OX=9913 GN=MORN5 PE=4 SV=1 CANONICAL=Q32LL6-1" }, "locus": { "chromosome": "11", "start_pos": 93081312, "end_pos": 93050324, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000139557.1", "url": "https://www.ensembl.org/id/ENSBTAT00000139557.1" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000107751.1", "url": "https://www.ensembl.org/id/ENSBTAP00000107751.1" } ] } }, { "isoform_ac": "Q32LL6-1", "url": "https://www.uniprot.org/uniprotkb/Q32LL6/entry#Q32LL6-1", "sequence": { "sequence": "MEYTGSQYIGEFVDGRMEGDAEYILPTETKYIGEMKDGMFHGQGTLYFPNGSRFDAVWEKGLVVKGTYTFSDGLQYDTENWHYCDSYDRRFYTEICYGLKPAGISQLTNMDPPRKIPPGCYDCGDGFYNPNTRIVKDYNYRFLRNADDDEHEWIVRTCRKGWDETMGPEPKS", "length": 172, "header": "sp|Q32LL6-1|MORN5_BOVIN Isoform 1 of MORN repeat-containing protein 5 OS=Bos taurus OX=9913 GN=MORN5 PE=1 SV=1 CANONICAL=Q32LL6-1" }, "locus": {} } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [ { "id": "bta:614076", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?bta:614076", "resource": "KEGG Pathway" } ], "orthologs": [], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 2, "go_terms": [ { "name": "sperm flagellum", "id": "GO:0036126", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0036126", "evidence": [ { "database": "UniProtKB", "id": "Q32LL6", "url": "https://www.uniprot.org/uniprotkb/Q32LL6" } ], "pmid": "" }, { "name": "motile cilium", "id": "GO:0031514", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0031514", "evidence": [ { "database": "UniProtKB", "id": "Q32LL6", "url": "https://www.uniprot.org/uniprotkb/Q32LL6" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 50, "end_pos": 52, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [ { "pdb_id": "AF-Q32LL6-F1", "pdb_chain": "global", "start_pos": 1, "end_pos": 172, "overlap": "1.0", "method": "AlphaFold", "type": "alphafold", "resolution": -1.0, "url": "https://data.glygen.org/ln2downloads/pdb/current/AF-Q32LL6-F1.pdb", "url_external": "https://alphafold.ebi.ac.uk/entry/Q32LL6" } ], "lectin_list": [], "domain_list": [], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 50, "end_pos": 52 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ], "tool_support": { "graph_view": "yes" } }, { "uniprot_canonical_ac": "Q58DF3-1", "uniprot_ac": "Q58DF3", "uniprot_id": "TRABD_BOVIN", "mass": { "chemical_mass": 42125.0, "monoisotopic_mass": 42125.0 }, "refseq": { "ac": "NP_001029624", "name": "traB domain-containing protein", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001029624" }, "gene_names": [ { "name": "TRABD", "type": "recommended", "evidence": [ { "id": "Q58DF3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q58DF3" } ] }, { "name": "PP2447", "type": "synonym", "evidence": [ { "id": "NP_001029624", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001029624" } ] }, { "name": "TRABD", "type": "synonym", "evidence": [ { "id": "NP_001029624", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001029624" } ] } ], "protein_names": [ { "name": "TraB domain-containing protein", "type": "recommended", "evidence": [ { "id": "Q58DF3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q58DF3/entry#names_and_taxonomy" } ] }, { "name": "traB domain-containing protein", "type": "synonym", "evidence": [ { "id": "NP_001029624", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001029624" } ] } ], "function": [ { "annotation": "Along with MFN2, MIGA2 and PLD6 promotes mitochondrial clustering and fusion. May play a role in mitochondrial import of proteins, such as that of SLC25A19.", "evidence": [ { "database": "UniProtKB", "id": "Q58DF3", "url": "https://www.uniprot.org/uniprotkb/Q58DF3#function" }, { "database": "UniProtKB", "id": "Q9H4I3", "url": "https://www.uniprot.org/uniprotkb/Q9H4I3#function" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Bos taurus", "taxid": 9913, "evidence": [ { "database": "UniProtKB", "id": "Q58DF3", "url": "https://www.uniprot.org/uniprotkb/Q58DF3" } ], "common_name": "Bovine", "glygen_name": "Bovine", "reference_species": "Bos taurus [9913]" } ], "gene": [ { "name": "TRABD", "url": "https://www.uniprot.org/uniprotkb/Q58DF3", "locus": { "chromosome": "5", "start_pos": 119564135, "end_pos": 119556874, "strand": "-", "evidence": [ { "database": "Ensembl Gene", "id": "ENSBTAG00000001931", "url": "https://www.ensembl.org/id/ENSBTAG00000001931" } ] } } ], "crossref": [ { "id": "Q58DF3", "url": "https://alphafold.ebi.ac.uk/entry/Q58DF3", "database": "AlphaFoldDB", "categories": [] }, { "id": "ENSBTAG00000001931", "url": "https://bgee.org/?page=gene&gene_id=ENSBTAG00000001931", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "cd14726", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd14726", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "513765", "url": "https://www.ncbi.nlm.nih.gov/gene/513765", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR002816", "url": "https://www.ebi.ac.uk/interpro/entry/IPR002816", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR046345", "url": "https://www.ebi.ac.uk/interpro/entry/IPR046345", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "bta:513765", "url": "https://www.genome.jp/dbget-bin/www_bget?bta:513765", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "MEKMMTT", "url": "https://omabrowser.org/oma/group/MEKMMTT/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "A0A3Q1LNP3", "url": "https://www.orthodb.org/?gene=A0A3Q1LNP3", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "Q58DF3", "url": "https://www.orthodb.org/?gene=Q58DF3", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR21530", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR21530", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR21530:SF7", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR21530:SF7", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF01963", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF01963", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "NP_001029624", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001029624", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A3Q1LNP3", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1LNP3", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A3Q1LNP3-1", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1LNP3-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "G3X6B5", "url": "https://www.uniprot.org/uniprotkb/G3X6B5", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "G3X6B5-1", "url": "https://www.uniprot.org/uniprotkb/G3X6B5-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "Q58DF3", "url": "https://www.uniprot.org/uniprotkb/Q58DF3", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "Q58DF3-1", "url": "https://www.uniprot.org/uniprotkb/Q58DF3-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MEEPEEQPPHEADTEPVVTSGASEAVPRVLPGDPQNLSDVDAFNLLLEMKLKRRRERPNLPHTVTELVAEDGSRVYVVGTAHFSDDSKRDVVKTIREVQPDVVVVELCQYRVSMLKMDERTLLREAKEISLEKLQQAIRQNGVASGLMQMLLLKVSAHITEQLGVAPGGEFREAFKEASRVPFCKFHLGDRPIPVTFKRAIAALSLWQKVKLAWGLCFLSDPISKDDVERCKQKDLLEQMMAEMVGEFPDLHRTIVSERDVYLTYMLRQAARRLELPRASDAEPRKCVPSVVVGVVGMGHVPGIEKNWTTDLNIQEIMTVPPPSASGRVSRLAVKAAALGLLGYGLYWTGRRAVSLLLALPAARHCLQRLSDAWPQK", "length": 377, "header": "sp|Q58DF3-1|TRABD_BOVIN Isoform 1 of TraB domain-containing protein OS=Bos taurus OX=9913 GN=TRABD PE=2 SV=1 CANONICAL=Q58DF3-1" }, "isoforms": [ { "isoform_ac": "A0A3Q1LNP3-1", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1LNP3/entry", "sequence": { "sequence": "MSCCLRGPLRHTPWFTCDRVGARAHNSTEPQPDQSCSSRDSPITCQTLQWARPVGAPQDPSPQLSWNRGFFSFRLHASVPELLPAMEEPEEQPPHEADTEPVVTSGASEAVPRVLPGDPQNLSDVDAFNLLLEMKLKRRRERPNLPHTVTELVAEDGSRVYVVGTAHFSDDSKRDVVKTIREVQPDVVVVELCQYRVSMLKMDERTLLREAKEISLEKLQQAIRQNGVASGLMQMLLLKVSAHITEQLGVAPGGEFREAFKEASRVPFCKFHLGDRPIPVTFKRAIAALSLWQKVKLAWGLCFLSDPISKDDVERCKQKDLLEQMMAEMVGEFPDLHRTIVSERDVYLTYMLRQAARRLELPRASDAEPRKCVPSVVVGVVGMGHVPGIEKNWTTDLNIQEIMTVPPPSASGRVSRLAVKAAALGLLGYGLYWTGRRAVSLLLALPAARHCLQRLSDAWPQK", "length": 462, "header": "tr|A0A3Q1LNP3-1|TRABD_BOVIN Computationally mapped isoform of TraB domain-containing protein OS=Bos taurus OX=9913 GN=TRABD PE=2 SV=1 CANONICAL=Q58DF3-1" }, "locus": { "chromosome": "5", "start_pos": 119564023, "end_pos": 119560372, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000082873.3", "url": "https://www.ensembl.org/id/ENSBTAT00000082873.3" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000061649.1", "url": "https://www.ensembl.org/id/ENSBTAP00000061649.1" } ] } }, { "isoform_ac": "G3X6B5-1", "url": "https://www.uniprot.org/uniprotkb/G3X6B5/entry", "sequence": { "sequence": "MEEPEEQPPHEADTEPVVTSGASEAVPRVLPGDPQNLSDVDAFNLLLEMKLKRRRERPNLPHTVTELVAEDGSRVYVVGTAHFSDDSKRDVVKTIREVQPDVVVVELCQYRVSMLKMDERTLLREAKEISLEKLQQAIRQNGVASGLMQMLLLKVSAHITEQLGVAPGGEFREAFKEASRVPFCKFHLGDRPIPVTFKRAIAALSLWQKVKLAWGLCFLSDPISKDDVERCKQKDLLEQMMAEMVGEFPDLHRTIVSERDVYLTYMLRQAARRLELPRASDGEHGARGHGAPRGRGCSGAHASPTPAEPRKCVPSVVVGVVGMGHVPGIEKNWTTDLNIQEIMTVPPPSASGRVSRLAVKAAALGLLGYGLYWTGRRAVSLLLALPAARHCLQRLSDAWPQK", "length": 402, "header": "tr|G3X6B5-1|G3X6B5_BOVIN Computationally mapped isoform of TraB domain containing OS=Bos taurus OX=9913 GN=TRABD PE=4 SV=1 CANONICAL=Q58DF3-1" }, "locus": { "chromosome": "5", "start_pos": 119564023, "end_pos": 119561574, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000002512.6", "url": "https://www.ensembl.org/id/ENSBTAT00000002512.6" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000002512.4", "url": "https://www.ensembl.org/id/ENSBTAP00000002512.4" } ] } }, { "isoform_ac": "Q58DF3-1", "url": "https://www.uniprot.org/uniprotkb/Q58DF3/entry#Q58DF3-1", "sequence": { "sequence": "MEEPEEQPPHEADTEPVVTSGASEAVPRVLPGDPQNLSDVDAFNLLLEMKLKRRRERPNLPHTVTELVAEDGSRVYVVGTAHFSDDSKRDVVKTIREVQPDVVVVELCQYRVSMLKMDERTLLREAKEISLEKLQQAIRQNGVASGLMQMLLLKVSAHITEQLGVAPGGEFREAFKEASRVPFCKFHLGDRPIPVTFKRAIAALSLWQKVKLAWGLCFLSDPISKDDVERCKQKDLLEQMMAEMVGEFPDLHRTIVSERDVYLTYMLRQAARRLELPRASDAEPRKCVPSVVVGVVGMGHVPGIEKNWTTDLNIQEIMTVPPPSASGRVSRLAVKAAALGLLGYGLYWTGRRAVSLLLALPAARHCLQRLSDAWPQK", "length": 377, "header": "sp|Q58DF3-1|TRABD_BOVIN Isoform 1 of TraB domain-containing protein OS=Bos taurus OX=9913 GN=TRABD PE=2 SV=1 CANONICAL=Q58DF3-1" }, "locus": {} } ], "glycosylation": [], "phosphorylation": [ { "start_pos": 65, "end_pos": 65, "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "residue": "Thr", "comment": "Phosphothreonine", "evidence": [ { "database": "UniProtKB", "id": "Q58DF3", "url": "https://www.uniprot.org/uniprotkb/Q58DF3" } ], "site_lbl": "Thr65" } ], "glycation": [], "keywords": [], "publication": [ { "title": "Characterization of 954 bovine full-CDS cDNA sequences.", "journal": "BMC Genomics", "date": "2005", "authors": "Harhay Gregory P, Sonstegard Tad S, Keele John W, Heaton Michael P, Clawson Michael L, Snelling Warren M, Wiedmann Ralph T, Van Tassell Curt P, Smith Timothy P L", "evidence": [ { "database": "UniProtKB", "id": "Q58DF3", "url": "https://www.uniprot.org/uniprotkb/Q58DF3" } ], "reference": [ { "type": "PubMed", "id": "16305752", "url": "https://glygen.org/publication/PubMed/16305752" } ] } ], "pathway": [ { "id": "bta:513765", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?bta:513765", "resource": "KEGG Pathway" } ], "orthologs": [ { "uniprot_canonical_ac": "D3ZML4-1", "protein_name": "TraB domain containing", "gene_name": "Trabd", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MEGEEKPAQEADVEPMVTSGASEAVPRVLSGDPQNISDVDAFNLLLEMKLKRRRERPNLPCTVTQLVAEDGSRVYVVGTAHFSDDSKRDVVKTIREVQPDVVVVELCQYRVSMLKMDERTLLREAKEVSLEKLQQAVKQNGLMSGLMQMLLLKVSAHITEQLGMAPGGEFREAFKEASKVPFCKFHLGDRPIPVTFKRAIAALSFWQKVKLAWGLCFLSDPISKDDVERCKQKDLLEQMMAEMIGEFPDLHRTIVSERDVYLTYMLRQAARRLELPRASDAEPRKCVPSVVVGVVGMGHVPGIEKNWSTDLNIQEIMTVPPPSITGRVSRAAVKAAFFGLLGYSLYWMGRRTVNLVLSLPAAQFCLQRVSEARPGR", "length": 376 }, "evidence": [ { "id": "Q58DF3", "url": "https://omabrowser.org/oma/group/Q58DF3/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "F4ITP5-1", "protein_name": "TraB family protein", "gene_name": "", "tax_id": 3702, "organism": "Arabidopsis thaliana", "sequence": { "sequence": "MELKPEVQYGDFSLTNSLVNVDKEDLRREEADSDAGSVIICDHSICDSGDGDICAVADYVECVAVETTEKLELPEEFAKSVMVLTCESTAEGGSCDVYLVGTAHVSQESCREVEAVISALKPQAVFLELCSSRLSILTPQTVKEPPTWMEMIYMWKKKHNLFEIVYGYILAKAAKKLEVFPGAEFRVGFEEANKYGGRVFLGDRSVQITLQRTWGKMPLWHKIKLVYSIVSQAVFLPNPKELEKMLKDLGDGDMLTLAIQEMSTEFPTLMETLVHERDKYMAYQLLRIASEHSSVVAVVGRGHLQGIKKNWNQTINIKELMELPTNESIFTVKNILKYMVVVVVGTAIVSGMYLAK", "length": 356 }, "evidence": [ { "id": "Q58DF3", "url": "https://omabrowser.org/oma/group/Q58DF3/", "database": "OMA" } ], "glygen_name": "Arabidopsis", "common_name": "Mouse-ear cress" }, { "uniprot_canonical_ac": "G3I2V0-1", "protein_name": "TraB domain-containing protein", "gene_name": "Trabd", "tax_id": 10029, "organism": "Cricetulus griseus", "sequence": { "sequence": "MEGEEKPTQETDMEPVVTSGASETVPRVPSGDPQNISDVDAFNLLLEMKLKRRRERPNLPRTVTQLVAEDGSRVYVVGTAHFSDDSKRDVVKTIREVQPDVVVVELCQYRVSMLKMDERTLLREAKEVSLEKLQQAVKQNGLMSGLMQMLLLKVSAHITEQLGMAPGGEFREAFKEASKVPFCKFHLGDRPIPVTFKRAIAALSFWQKVKLAWGLCFLSDPISKDDVERCKQKDLLEQMMAEMIGEFPDLHRTIVSERDVYLTYMLRQAARRLELPRASDAEPRKCVPSVVVGVVGMGHVPGIEKNWSTDLNIQEIMTVPPPSISGRVSRVAVKAAFFGLLGYSLYWMGRRTMNLVLSLPAAQFCLQRVSEARPGR", "length": 376 }, "evidence": [ { "id": "Q58DF3", "url": "https://omabrowser.org/oma/group/Q58DF3/", "database": "OMA" } ], "glygen_name": "Hamster", "common_name": "Chinese hamster" }, { "uniprot_canonical_ac": "Q99JY4-1", "protein_name": "TraB domain-containing protein", "gene_name": "Trabd", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MEGEEKPAQEADVEPVVTAGTSEAVPRVLAGDPQNISDVDAFNLLLEMKLKRRRERPNLPRTVTQLVAEDGSRVYVVGTAHFSDDSKRDVVKTIREVQPDVVVVELCQYRVSMLKMDERTLLREAKEVSLEKLQQAVRQNGLMSGLMQMLLLKVSAHITEQLGMAPGGEFREAFKEASKVPFCKFHLGDRPIPVTFKRAIAALSFWQKVKLAWGLCFLSDPISKDDVERCKQKDLLEQMMAEMIGEFPDLHRTIVSERDVYLTYMLRQAARRLELPRASDAEPRKCVPSVVVGVVGMGHVPGIEKNWSTDLNIQEIMTVPPPSISGRVSRVAVKAAFFGLLGYSLYWMGRRTLNLVLSLPAAQFCLQRVSEARPGR", "length": 376 }, "evidence": [ { "id": "Q58DF3", "url": "https://omabrowser.org/oma/group/Q58DF3/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q9H4I3-1", "protein_name": "TraB domain-containing protein", "gene_name": "TRABD", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MDGEEQQPPHEANVEPVVPSEASEPVPRVLSGDPQNLSDVDAFNLLLEMKLKRRRQRPNLPRTVTQLVAEDGSRVYVVGTAHFSDDSKRDVVKTIREVQPDVVVVELCQYRVSMLKMDESTLLREAQELSLEKLQQAVRQNGLMSGLMQMLLLKVSAHITEQLGMAPGGEFREAFKEASKVPFCKFHLGDRPIPVTFKRAIAALSFWQKVRLAWGLCFLSDPISKDDVERCKQKDLLEQMMAEMIGEFPDLHRTIVSERDVYLTYMLRQAARRLELPRASDAEPRKCVPSVVVGVVGMGHVPGIEKNWSTDLNIQEIMTVPPPSVSGRVSRLAVKAAFFGLLGYSLYWMGRRTASLVLSLPAAQYCLQRVTEARHK", "length": 376 }, "evidence": [ { "id": "Q58DF3", "url": "https://omabrowser.org/oma/group/Q58DF3/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" } ], "go_annotation": { "categories": [ { "name": "Biological Process", "total": 2, "go_terms": [ { "name": "protein localization to mitochondrion", "id": "GO:0070585", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0070585", "evidence": [ { "database": "UniProtKB", "id": "Q58DF3", "url": "https://www.uniprot.org/uniprotkb/Q58DF3" } ], "pmid": "" }, { "name": "mitochondrial fusion", "id": "GO:0008053", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008053", "evidence": [ { "database": "UniProtKB", "id": "Q58DF3", "url": "https://www.uniprot.org/uniprotkb/Q58DF3" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 2, "go_terms": [ { "name": "mitochondrial outer membrane", "id": "GO:0005741", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005741", "evidence": [ { "database": "UniProtKB", "id": "Q58DF3", "url": "https://www.uniprot.org/uniprotkb/Q58DF3" } ], "pmid": "" }, { "name": "TOM complex", "id": "GO:0140596", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0140596", "evidence": [ { "database": "UniProtKB", "id": "Q58DF3", "url": "https://www.uniprot.org/uniprotkb/Q58DF3" } ], "pmid": "" } ] }, { "name": "Molecular Function", "total": 1, "go_terms": [ { "name": "mitochondrion-mitochondrion outer membrane tether activity", "id": "GO:0160204", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0160204", "evidence": [ { "database": "UniProtKB", "id": "Q58DF3", "url": "https://www.uniprot.org/uniprotkb/Q58DF3" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 307, "end_pos": 309, "annotation": "n_glycosylation_sequon" }, { "start_pos": 36, "end_pos": 38, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [ { "pdb_id": "AF-Q58DF3-F1", "pdb_chain": "global", "start_pos": 1, "end_pos": 377, "overlap": "1.0", "method": "AlphaFold", "type": "alphafold", "resolution": -1.0, "url": "https://data.glygen.org/ln2downloads/pdb/current/AF-Q58DF3-F1.pdb", "url_external": "https://alphafold.ebi.ac.uk/entry/Q58DF3" } ], "lectin_list": [], "domain_list": [], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" }, { "name": "homologset.oma", "label": "OMA Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [ 65 ], "sequon_annotation_sites": [ { "start_pos": 307, "end_pos": 309 }, { "start_pos": 36, "end_pos": 38 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 1 }, { "field": "total_sites", "count": 1 } ], "sort_fields": [ "start_pos", "end_pos", "kinase_uniprot_canonical_ac", "kinase_gene_name", "residue", "comment", "site_lbl" ] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ], "tool_support": { "graph_view": "yes" } }, { "uniprot_canonical_ac": "M5FKI5-1", "uniprot_ac": "M5FKI5", "uniprot_id": "M5FKI5_BOVIN", "mass": { "chemical_mass": 147102.0, "monoisotopic_mass": 147102.0 }, "refseq": {}, "gene_names": [ { "name": "MAPK8IP3", "type": "recommended", "evidence": [ { "id": "M5FKI5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/M5FKI5" } ] } ], "protein_names": [ { "name": "C-Jun-amino-terminal kinase-interacting protein 3", "type": "recommended", "evidence": [ { "id": "M5FKI5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/M5FKI5/entry#names_and_taxonomy" } ] }, { "name": "JNK MAP kinase scaffold protein 3", "type": "synonym", "evidence": [ { "id": "M5FKI5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/M5FKI5/entry#names_and_taxonomy" } ] } ], "function": [], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Bos taurus", "taxid": 9913, "evidence": [ { "database": "UniProtKB", "id": "M5FKI5", "url": "https://www.uniprot.org/uniprotkb/M5FKI5" } ], "common_name": "Bovine", "glygen_name": "Bovine", "reference_species": "Bos taurus [9913]" } ], "gene": [ { "name": "MAPK8IP3", "url": "https://www.uniprot.org/uniprotkb/M5FKI5", "locus": { "chromosome": "25", "start_pos": 1349468, "end_pos": 1305496, "strand": "-", "evidence": [ { "database": "Ensembl Gene", "id": "ENSBTAG00000002211", "url": "https://www.ensembl.org/id/ENSBTAG00000002211" } ] } } ], "crossref": [ { "id": "ENSBTAG00000002211", "url": "https://bgee.org/?page=gene&gene_id=ENSBTAG00000002211", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "537598", "url": "https://www.ncbi.nlm.nih.gov/gene/537598", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR015943", "url": "https://www.ebi.ac.uk/interpro/entry/IPR015943", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR032486", "url": "https://www.ebi.ac.uk/interpro/entry/IPR032486", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR034743", "url": "https://www.ebi.ac.uk/interpro/entry/IPR034743", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR034744", "url": "https://www.ebi.ac.uk/interpro/entry/IPR034744", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR036322", "url": "https://www.ebi.ac.uk/interpro/entry/IPR036322", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR039911", "url": "https://www.ebi.ac.uk/interpro/entry/IPR039911", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "E1BN82", "url": "https://www.orthodb.org/?gene=E1BN82", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "M5FKI5", "url": "https://www.orthodb.org/?gene=M5FKI5", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR13886", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR13886", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR13886:SF3", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR13886:SF3", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF09744", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF09744", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF16471", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF16471", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF19056", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF19056", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "E1BN82", "url": "https://www.uniprot.org/uniprotkb/E1BN82", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "E1BN82-1", "url": "https://www.uniprot.org/uniprotkb/E1BN82-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "M5FKI5", "url": "https://www.uniprot.org/uniprotkb/M5FKI5", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "M5FKI5-1", "url": "https://www.uniprot.org/uniprotkb/M5FKI5-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MMEIQMDEGGGVVVYQDDYCSGSVMSERVSGLAGSIYREFERLIHCYDEEVVKELMPLVVNVLENLDSVLSENQEHEVELELLREDNEQLLTQYEREKSLRKQAEEKFIEFEDALEQEKKELQIQVEHYEFQTRQLELKAKNYADQISRLEERESEMKKEYNALHQRHTEMIQTYVEHIERSKMQQVGGNSQTEGSLPGRSPRQSWRRSRKERPTSLSVFPLADGSVRAQMGGKPVPAGDHWHLSDLGQLQLSSSYQCPQDEMSESGQSSAAATPSTTGTKSNTPTSSVPSAAVTPLSEGLQPLGDYGGSKNGKRAREKRNSRNMEVQVTQEMRNVSIGMGSSDEWSDVQDIIDSTPELDMGREPRLDRTGSSPTQGIVNKAFGINTDSLYHELSTAGSEVIGDVDEGADLLGEFSGMGKEVGNLLLENSQLLETKNALNVVKNDLIAKVDQLSGEQEALKGDLEAARQAKLRLENRIKDLEEELRRVKSEAITAHREPKEEVEDVSSCLCTELDKIPMAQRRRFTRVEMARVLMERNQYKERLMELQEAVRWTEMIRASREHPSVQEKKKSTIWQFFSRLFSSSSSPPPAKRSYPSVNIHYKSPTTAGFSQRRNHGMCQSSAGSRPLEFFPDDDCTSSARREQKREQYRQVREHVRNDDGRLQACGWSLPAKYKQLSPNGGQEDTRMKNVPVPVYCRPLVEKDPTMKLWCAAGVNLSGWKLSEDGPGNGVKPAPGRDPLTCDREVEGEAKSNHASPEKKKAKELPEADATSSRVWILTSTLTTSKVVVIDANQPGTVVDQFTVCNAHVLCISSIPAASDGDYPPGEIFLDSDVNPEDSGADGVLAGITLVGCATRCNVPRSNCSSRGDTPVLDKGQGEVSAVANGKVNPAPSTEEATEATEVPDAGPSEAEAAAVRPGPLTEHVFTDPAPTPPPSTQPDSENGPEADVSGVQPEPEPSGDPAGSTSAAPTMWLGAQNGWLYVHSAVANWKKCLHSIKLKDSVLSLVHVKGRVLVALADGTLAIFHRGEDGQWDLSNYHLMDLGHPHHSIRCMAVVHDRVWCGYKNKVHVIQPKTMQIEKSFDAHPRRESQVRQLAWIGDGVWVSIRLDSTLRLYHAHTHQHLQDVDIEPYVSKMLGTGKLGFSFVRITALLIAGNRLWVGTGNGVVISIPLTETVVLHRGQLLGLRANKTSPTSGEGARPGGVIHVYGDDSSDRAASSFIPYCSMAQAQLCFHGHRDAVKFFVSVPGNVLATLNGSVLDSPSEGPGPTAPAADAEAQKLKNVLVLSGGEGYIDFRIGDGEDDEPEEGAGDVSQVKPVLSKAERSHIIVWQVSYTPE", "length": 1337, "header": "tr|M5FKI5-1|M5FKI5_BOVIN Isoform 1 of C-Jun-amino-terminal kinase-interacting protein 3 OS=Bos taurus OX=9913 GN=MAPK8IP3 PE=3 SV=2 CANONICAL=M5FKI5-1" }, "isoforms": [ { "isoform_ac": "E1BN82-1", "url": "https://www.uniprot.org/uniprotkb/E1BN82/entry", "sequence": { "sequence": "MMEIQMDEGGGVVVYQDDYCSGSVMSERVSGLAGSIYREFERLIHCYDEEVVKELMPLVVNVLENLDSVLSENQEHEVELELLREDNEQLLTQYEREKSLRKQAEEKFIEFEDALEQEKKELQIQVEHYEFQTRQLELKAKNYADQISRLEERESEMKKEYNALHQRHTEMIQTYVEHIERSKMQQVGGNSQTEGSLPGRSRKERPTSLSVFPLADGSVRAQMGGKPVPAGDHWHLSDLGQLQLSSSYQCPQDEMSESGQSSAAATPSTTGTKSNTPTSSVPSAAVTPLSEGLQPLGDYGGSKNGKRAREKRNSRNMEVQVTQEMRNVSIGMGSSDEWSDVQDIIDSTPELDMGREPRLDRTGSSPTQGIVNKAFGINTDSLYHELSTAGSEVIGDVDEGADLLGEFSVRDDFFGMGKEVGNLLLENSQLLETKNALNVVKNDLIAKVDQLSGEQEALKGDLEAARQAKLRLENRIKDLEEELRRVKSEAITAHREPKEEVEDVSSCLCTELDKIPMAQRRRFTRVEMARVLMERNQYKERLMELQEAVRWTEMIRASREHPSVQEKKKSTIWQFFSRLFSSSSSPPPAKRSYPSVNIHYKSPTTAGFSQRRNHGMCQSSAGSRPLEFFPDDDCTSSARREQKREQYRQVREHVRNDDGRLQACGWSLPAKYKQLSPNGGQEDTRMKNVPVPVYCRPLVEKDPTMKLWCAAGVNLSGWKLSEDGPGNGVKPAPGRDPLTCDREVEGEAKSNHASPEKKKAKELPEADATSSRVWILTSTLTTSKVVVIDANQPGTVVDQFTVCNAHVLCISSIPAASDGDYPPGEIFLDSDVNPEDSGADGVLAGITLVGCATRCNVPRSNCSSRGDTPVLDKGQGEVSAVANGKVNPAPSTEEATEATEVPDAGPSEAEAAAVRPGPLTEHVFTDPAPTPPPSTQPDSENGPEADVSGVQPEPEPSGDPAGSTSAAPTMWLGAQNGWLYVHSAVANWKKCLHSIKLKDSVLSLVHVKGRVLVALADGTLAIFHRGEDGQWDLSNYHLMDLGHPHHSIRCMAVVHDRVWCGYKNKVHVIQPKTMQIEKSFDAHPRRESQVRQLAWIGDGVWVSIRLDSTLRLYHAHTHQHLQDVDIEPYVSKMLGTGKLGFSFVRITALLIAGNRLWVGTGNGVVISIPLTETVVLHRGQLLGLRANKTSPTSGEGARPGGVIHVYGDDSSDRAASSFIPYCSMAQAQLCFHGHRDAVKFFVSVPGNVLATLNGSVLDSPSEGPGPTAPAADAEAQKLKNVLVLSGGEGYIDFRIGDGEDDEPEEGAGDVSQVKPVLSKAERSHIIVWQVSYTPE", "length": 1335, "header": "tr|E1BN82-1|M5FKI5_BOVIN Computationally mapped isoform of C-Jun-amino-terminal kinase-interacting protein 3 OS=Bos taurus OX=9913 GN=MAPK8IP3 PE=3 SV=4 CANONICAL=M5FKI5-1" }, "locus": { "chromosome": "25", "start_pos": 1348022, "end_pos": 1305664, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000002865.8", "url": "https://www.ensembl.org/id/ENSBTAT00000002865.8" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000002865.7", "url": "https://www.ensembl.org/id/ENSBTAP00000002865.7" } ] } }, { "isoform_ac": "M5FKI5-1", "url": "https://www.uniprot.org/uniprotkb/M5FKI5/entry", "sequence": { "sequence": 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"NP_001070547", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001070547" } ] }, { "name": "C3H1orf185", "type": "synonym", "evidence": [ { "id": "NP_001070547", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001070547" } ] } ], "protein_names": [ { "name": "Uncharacterized protein C1orf185 homolog", "type": "recommended", "evidence": [ { "id": "Q2M2T8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q2M2T8/entry#names_and_taxonomy" } ] }, { "name": "uncharacterized protein C1orf185 homolog", "type": "synonym", "evidence": [ { "id": "NP_001070547", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001070547" } ] } ], "function": [], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Bos taurus", "taxid": 9913, "evidence": [ { "database": "UniProtKB", "id": "Q2M2T8", "url": "https://www.uniprot.org/uniprotkb/Q2M2T8" } ], "common_name": "Bovine", "glygen_name": "Bovine", "reference_species": "Bos taurus [9913]" } ], "gene": [ { "name": "", "url": "https://www.uniprot.org/uniprotkb/Q2M2T8", "locus": {} } ], "crossref": [ { "id": "Q2M2T8", "url": "https://alphafold.ebi.ac.uk/entry/Q2M2T8", "database": "AlphaFoldDB", "categories": [] }, { "id": "ENSBTAG00000009674", "url": "https://bgee.org/?page=gene&gene_id=ENSBTAG00000009674", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "768020", "url": "https://www.ncbi.nlm.nih.gov/gene/768020", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR031695", "url": "https://www.ebi.ac.uk/interpro/entry/IPR031695", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "bta:768020", "url": "https://www.genome.jp/dbget-bin/www_bget?bta:768020", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "TKSHSQC", "url": "https://omabrowser.org/oma/group/TKSHSQC/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "F1MRQ2", "url": "https://www.orthodb.org/?gene=F1MRQ2", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "Q2M2T8", "url": "https://www.orthodb.org/?gene=Q2M2T8", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR37858", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR37858", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR37858:SF1", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR37858:SF1", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF15842", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF15842", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "NP_001070547", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001070547", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0AAA9SDV8", "url": "https://www.uniprot.org/uniprotkb/A0AAA9SDV8", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0AAA9SDV8-1", "url": "https://www.uniprot.org/uniprotkb/A0AAA9SDV8-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "F1MRQ2", "url": "https://www.uniprot.org/uniprotkb/F1MRQ2", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "F1MRQ2-1", "url": "https://www.uniprot.org/uniprotkb/F1MRQ2-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "Q2M2T8", "url": "https://www.uniprot.org/uniprotkb/Q2M2T8", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "Q2M2T8-1", "url": "https://www.uniprot.org/uniprotkb/Q2M2T8-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MASPNGFFNHLTYFLAAGAVTLGIGFFALASALWFLICKRREIFQDSKFKAVDEKCRQRPSKAKIKSHPQCVFISRNFHTGRFQSQEEQRKKETACIKANNGYSKDDFCLATKKVICDPSESSSATNPSSVTLSLSTLPSDFYYSQSVEIADDWYSDDSQMKKSPSMPFLGEPLMEKVFSYLTTIPLEQCTENVLNMTLRDDQKDDNLKEIFTQRNTEVEIQNLQHNTE", "length": 229, "header": "sp|Q2M2T8-1|CA185_BOVIN Isoform 1 of Uncharacterized protein C1orf185 homolog OS=Bos taurus OX=9913 GN= PE=2 SV=1 CANONICAL=Q2M2T8-1" }, "isoforms": [ { "isoform_ac": "A0AAA9SDV8-1", "url": "https://www.uniprot.org/uniprotkb/A0AAA9SDV8/entry", "sequence": { "sequence": "FFNHLTYFLAAGAVTLGIGFFALASALWFLICKRREIFQDSKFKAVDEKCRQRPSKAKIKSHPQCVFISRNFHTGRFQSQQIMVILKMISALQQKKSFVTPQSLARQQIPAVLP", "length": 114, "header": "tr|A0AAA9SDV8-1|CA185_BOVIN Computationally mapped isoform of Uncharacterized protein C1orf185 homolog OS=Bos taurus OX=9913 GN= PE=2 SV=1 CANONICAL=Q2M2T8-1" }, "locus": { "chromosome": "3", "start_pos": 95174821, "end_pos": 95141209, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000102899.1", "url": "https://www.ensembl.org/id/ENSBTAT00000102899.1" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000081993.1", "url": "https://www.ensembl.org/id/ENSBTAP00000081993.1" } ] } }, { "isoform_ac": "F1MRQ2-1", "url": "https://www.uniprot.org/uniprotkb/F1MRQ2/entry", "sequence": { "sequence": "SGFFNHLTYFLAAGAVTLGIGFFALASALWFLICKRREIFQDSKFKAVDEKCRQRPSKAKIKSHPQCVFISRNFHTGRFQSQEEQRKKETACIKANNGYSKDDFCLATKKVICDPSESSSATNPSSVTLSLSTLPSDFYYSQSVEIADDWYSDDSQMKKSPSMPFLGEPLMEKVFSYLTTIPLEQCTENVLNMTLRDDQKDDNLKEIFTQRNTEVEIQNLQHNTE", "length": 225, "header": "tr|F1MRQ2-1|CA185_BOVIN Computationally mapped isoform of Uncharacterized protein C1orf185 homolog OS=Bos taurus OX=9913 GN= PE=2 SV=4 CANONICAL=Q2M2T8-1" }, "locus": { "chromosome": "3", "start_pos": 95174958, "end_pos": 95140919, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000012762.6", "url": "https://www.ensembl.org/id/ENSBTAT00000012762.6" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000012762.6", "url": "https://www.ensembl.org/id/ENSBTAP00000012762.6" } ] } }, { "isoform_ac": "Q2M2T8-1", "url": "https://www.uniprot.org/uniprotkb/Q2M2T8/entry#Q2M2T8-1", "sequence": { "sequence": "MASPNGFFNHLTYFLAAGAVTLGIGFFALASALWFLICKRREIFQDSKFKAVDEKCRQRPSKAKIKSHPQCVFISRNFHTGRFQSQEEQRKKETACIKANNGYSKDDFCLATKKVICDPSESSSATNPSSVTLSLSTLPSDFYYSQSVEIADDWYSDDSQMKKSPSMPFLGEPLMEKVFSYLTTIPLEQCTENVLNMTLRDDQKDDNLKEIFTQRNTEVEIQNLQHNTE", "length": 229, "header": "sp|Q2M2T8-1|CA185_BOVIN Isoform 1 of Uncharacterized protein C1orf185 homolog OS=Bos taurus OX=9913 GN= PE=2 SV=1 CANONICAL=Q2M2T8-1" }, "locus": { "chromosome": "3", "start_pos": 95186049, "end_pos": 95140919, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000073826.2", "url": "https://www.ensembl.org/id/ENSBTAT00000073826.2" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000058081.1", "url": "https://www.ensembl.org/id/ENSBTAP00000058081.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [ { "id": "bta:768020", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?bta:768020", "resource": "KEGG Pathway" } ], "orthologs": [ { "uniprot_canonical_ac": "F1LT57-1", "protein_name": "Similar to human chromosome 1 open reading frame 185", "gene_name": "C5h1orf185", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MGFFSHLTYFLAAGAVSLGIGFFALASALWFLICKRREIFESSNFKAISEKVNQGSCKPKLKAHPQCVFISRNFHVGQSQQVEKKEREEEQIKAIRNHSKVEFCTLDPASRESPEMTSVVNGSSVATMSVSTSMSSSYCSQSVEAAEDWFSDNSLEAKNPSKPLLGEPLAEKVLAYLSSISLEEWPGNSANTTFCSAEKAESVKEMFVQKNTEVSKHNLQFDIE", "length": 224 }, "evidence": [ { "id": "Q2M2T8", "url": "https://omabrowser.org/oma/group/Q2M2T8/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "Q5T7R7-1", "protein_name": "Uncharacterized protein C1orf185", "gene_name": "C1orf185", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MASPKGFFNYLTYFLAAGAVTLGIGFFALASALWFLICKRREIFQNSKFKAIDERCRQRPSMAKIKSHSQCVFISRNFHTGRFQLQEEQRKKEAAHIKAIKDHSKDEPQLATKNIICDPSETSSTTNRSSVTLSLSTLPSDSYYSQSIEAADDWFSDDSLVKRNSPMPSLGEPLMEKVFSYLSTISLEEGTESVLNDTL", "length": 199 }, "evidence": [ { "id": "Q2M2T8", "url": "https://omabrowser.org/oma/group/Q2M2T8/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "Q9CPZ3-1", "protein_name": "Uncharacterized protein C1orf185 homolog", "gene_name": "", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MTSPNGVFSHLTYFMAAGALSLGIGFFALASALWFLICKRRELFEESKFKEFGENMKQGSCKPKLKAHPQCVFISRNFHAGYLQSQTEKREKEEAEKKAVRSHSKVEFCLQDPISCESPEVTSVANGSSVSTLSLSTSISSSYCCQTVEEAEDWLTDDCLETRIPLKNPLLGEPLKKKVLAYLSSISLEEWPGNTVSNTFCSEQKTDSLKELLVLKNTEVGKHNLQFDIE", "length": 230 }, "evidence": [ { "id": "Q2M2T8", "url": "https://omabrowser.org/oma/group/Q2M2T8/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" } ], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 1, "go_terms": [ { "name": "membrane", "id": "GO:0016020", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016020", "evidence": [ { "database": "UniProtKB", "id": "Q2M2T8", "url": "https://www.uniprot.org/uniprotkb/Q2M2T8" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 196, "end_pos": 198, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [ { "pdb_id": "AF-Q2M2T8-F1", "pdb_chain": "global", "start_pos": 1, "end_pos": 229, "overlap": "1.0", "method": "AlphaFold", "type": "alphafold", "resolution": -1.0, "url": "https://data.glygen.org/ln2downloads/pdb/current/AF-Q2M2T8-F1.pdb", "url_external": "https://alphafold.ebi.ac.uk/entry/Q2M2T8" } ], "lectin_list": [], "domain_list": [], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" }, { "name": "homologset.oma", "label": "OMA Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 196, "end_pos": 198 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ], "tool_support": { "graph_view": "yes" } }, { "uniprot_canonical_ac": "G5E6B5-1", "uniprot_ac": "G5E6B5", "uniprot_id": "G5E6B5_BOVIN", "mass": { "chemical_mass": 13060.0, "monoisotopic_mass": 13060.0 }, "refseq": {}, "gene_names": [], "protein_names": [ { "name": "Ig-like domain-containing protein", "type": "recommended", "evidence": [ { "id": "G5E6B5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G5E6B5/entry#names_and_taxonomy" } ] } ], "function": [], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Bos taurus", "taxid": 9913, "evidence": [ { "database": "UniProtKB", "id": "G5E6B5", "url": "https://www.uniprot.org/uniprotkb/G5E6B5" } ], "common_name": "Bovine", "glygen_name": "Bovine", "reference_species": "Bos taurus [9913]" } ], "gene": [ { "name": "", "url": "https://www.uniprot.org/uniprotkb/G5E6B5", "locus": {} } ], "crossref": [ { "id": "G5E6B5", "url": "https://alphafold.ebi.ac.uk/entry/G5E6B5", "database": "AlphaFoldDB", "categories": [] }, { "id": "ENSBTAG00000035945", "url": "https://bgee.org/?page=gene&gene_id=ENSBTAG00000035945", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "IPR003597", "url": "https://www.ebi.ac.uk/interpro/entry/IPR003597", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR007110", "url": "https://www.ebi.ac.uk/interpro/entry/IPR007110", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR013783", "url": "https://www.ebi.ac.uk/interpro/entry/IPR013783", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR036179", "url": "https://www.ebi.ac.uk/interpro/entry/IPR036179", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR051117", "url": "https://www.ebi.ac.uk/interpro/entry/IPR051117", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "PTHR19256", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR19256", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR19256:SF65", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR19256:SF65", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF07654", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF07654", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "G5E6B5", "url": "https://www.uniprot.org/uniprotkb/G5E6B5", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "G5E6B5-1", "url": "https://www.uniprot.org/uniprotkb/G5E6B5-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "DRDLDIDMSPKPTMFLPSITEIKRENTGTYLCLLENFFPHVIKVYWREKRGNRVLPSQQGNTVKTADTYMKFSWLTVSGNSMDKEHICIVKHEKNKRGDNQEILFPPVNEGM", "length": 112, "header": "tr|G5E6B5-1|G5E6B5_BOVIN Isoform 1 of Ig-like domain-containing protein OS=Bos taurus OX=9913 GN= PE=4 SV=4 CANONICAL=G5E6B5-1" }, "isoforms": [ { "isoform_ac": "G5E6B5-1", "url": "https://www.uniprot.org/uniprotkb/G5E6B5/entry", "sequence": { "sequence": "DRDLDIDMSPKPTMFLPSITEIKRENTGTYLCLLENFFPHVIKVYWREKRGNRVLPSQQGNTVKTADTYMKFSWLTVSGNSMDKEHICIVKHEKNKRGDNQEILFPPVNEGM", "length": 112, "header": "tr|G5E6B5-1|G5E6B5_BOVIN Isoform 1 of Ig-like domain-containing protein OS=Bos taurus OX=9913 GN= PE=4 SV=4 CANONICAL=G5E6B5-1" }, "locus": { "chromosome": "4", "start_pos": 82706314, "end_pos": 82705979, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000056327.5", "url": "https://www.ensembl.org/id/ENSBTAT00000056327.5" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000050018.5", "url": "https://www.ensembl.org/id/ENSBTAP00000050018.5" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [], "orthologs": [], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 1, "go_terms": [ { "name": "membrane", "id": "GO:0016020", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016020", "evidence": [ { "database": "UniProtKB", "id": "G5E6B5", "url": "https://www.uniprot.org/uniprotkb/G5E6B5" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "G5E6B5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G5E6B5" }, { "id": "PS50835", "database": "PROSITE", "url": "https://prosite.expasy.org/PS50835" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "Ig-like", "eco_id": "ECO_0000259", "start_pos": 10, "end_pos": 104, "start_aa": "Pro", "end_aa": "Leu", "glycosite_overlap": [] } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ], "tool_support": { "graph_view": "yes" } }, { "uniprot_canonical_ac": "P26818-1", "uniprot_ac": "P26818", "uniprot_id": "GRK3_BOVIN", "mass": { "chemical_mass": 79804.0, "monoisotopic_mass": 79804.0 }, "refseq": { "ac": "NP_776925", "name": "G protein-coupled receptor kinase 3", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_776925" }, "gene_names": [ { "name": "GRK3", "type": "recommended", "evidence": [ { "id": "P26818", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P26818" } ] }, { "name": "ADRBK2", "type": "synonym", "evidence": [ { "id": "NP_776925", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_776925" }, { "id": "P26818", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P26818" } ] }, { "name": "GRK3", "type": "synonym", "evidence": [ { "id": "NP_776925", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_776925" } ] } ], "protein_names": [ { "name": "G protein-coupled receptor kinase 3", "type": "recommended", "evidence": [ { "id": "P26818", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P26818/entry#names_and_taxonomy" } ] }, { "name": "2.7.11.15", "type": "synonym", "evidence": [ { "id": "P26818", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P26818/entry#names_and_taxonomy" } ] }, { "name": "2.7.11.16", "type": "synonym", "evidence": [ { "id": "P26818", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P26818/entry#names_and_taxonomy" } ] }, { "name": "Beta-ARK-2", "type": "synonym", "evidence": [ { "id": "P26818", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P26818/entry#names_and_taxonomy" } ] }, { "name": "Beta-adrenergic receptor kinase 2", "type": "synonym", "evidence": [ { "id": "P26818", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P26818/entry#names_and_taxonomy" } ] }, { "name": "G protein-coupled receptor kinase 3", "type": "synonym", "evidence": [ { "id": "NP_776925", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_776925" } ] }, { "name": "adrenergic, beta, receptor kinase 2", "type": "synonym", "evidence": [ { "id": "NP_776925", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_776925" } ] }, { "name": "beta-ARK-2", "type": "synonym", "evidence": [ { "id": "NP_776925", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_776925" } ] }, { "name": "beta-adrenergic receptor kinase 2", "type": "synonym", "evidence": [ { "id": "NP_776925", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_776925" } ] } ], "function": [ { "annotation": "Fusion proteins containing the c-terminus of GPCR kinase 3 (GRK3ct) and either the fluorescent protein cerulean or Renilla luciferase bind to venus-labeled Gbetagamma dimers, resulting in Forster or bioluminescence resonance energy transfer.", "evidence": [ { "database": "RefSeq", "id": "NP_776925", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_776925" }, { "database": "PubMed", "id": "19258039", "url": "https://glygen.org/publication/PubMed/19258039" } ] }, { "annotation": "Specifically phosphorylates the activated forms of G protein-coupled receptors (PubMed:10508278). Such receptor phosphorylation initiates beta-arrestin-mediated receptor internalization, and signaling events leading to their desensitization (PubMed:10508278). Phosphorylates the agonist-occupied form of the beta-adrenergic and closely related receptors (By similarity). Also phosphorylates ligand-bound C3a and C5a anaphylatoxin receptors (C3AR1 and C5AR1, respectively), leading to receptor desensitization (PubMed:10508278). Positively regulates ciliary smoothened (SMO) signaling pathway by mediating phosphorylation of SMO, facilitating SMO trafficking into the cilium and the stimulation of SMO activity (By similarity).", "evidence": [ { "database": "UniProtKB", "id": "P26818", "url": "https://www.uniprot.org/uniprotkb/P26818#function" }, { "database": "UniProtKB", "id": "P26819", "url": "https://www.uniprot.org/uniprotkb/P26819#function" }, { "database": "PubMed", "id": "10508278", "url": "https://glygen.org/publication/PubMed/10508278" }, { "database": "UniProtKB", "id": "Q3UYH7", "url": "https://www.uniprot.org/uniprotkb/Q3UYH7#function" } ] }, { "annotation": "receptors. Also phosphorylates ligand-bound C3a and C5a anaphylatoxin receptors (C3AR1 and C5AR1, respectively), leading to receptor desensitization.", "evidence": [ { "database": "UniProtKB", "id": "A0A3Q1LVI8", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1LVI8#function" }, { "database": "UniProtKB", "id": "ARBA00094365", "url": "https://www.uniprot.org/uniprotkb/ARBA00094365#function" }, { "database": "UniProtKB", "id": "A0AAF6YGR0", "url": "https://www.uniprot.org/uniprotkb/A0AAF6YGR0#function" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Bos taurus", "taxid": 9913, "evidence": [ { "database": "UniProtKB", "id": "P26818", "url": "https://www.uniprot.org/uniprotkb/P26818" } ], "common_name": "Bovine", "glygen_name": "Bovine", "reference_species": "Bos taurus [9913]" } ], "gene": [ { "name": "GRK3", "url": "https://www.uniprot.org/uniprotkb/P26818", "locus": { "chromosome": "17", "start_pos": 65505324, "end_pos": 65389743, "strand": "-", "evidence": [ { "database": "Ensembl Gene", "id": "ENSBTAG00000000005", "url": "https://www.ensembl.org/id/ENSBTAG00000000005" } ] } } ], "crossref": [ { "id": "P26818", "url": "https://alphafold.ebi.ac.uk/entry/P26818", "database": "AlphaFoldDB", "categories": [] }, { "id": "ENSBTAG00000000005", "url": "https://bgee.org/?page=gene&gene_id=ENSBTAG00000000005", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "2.7.11.15", "url": "https://www.brenda-enzymes.org/enzyme.php?ecno=2.7.11.15&UniProtAcc=P26818", "database": "BRENDA", "categories": [ "Enzyme and Pathway" ] }, { "id": "cd01240", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd01240", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "cd05633", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd05633", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "cd08747", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd08747", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "CHEMBL3711487", "url": "https://www.ebi.ac.uk/chembl/target/inspect/CHEMBL3711487", "database": "ChEMBL", "categories": [ "Chemical" ] }, { "id": "282136", "url": "https://www.ncbi.nlm.nih.gov/gene/282136", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR000239", "url": "https://www.ebi.ac.uk/interpro/entry/IPR000239", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR000719", "url": "https://www.ebi.ac.uk/interpro/entry/IPR000719", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR000961", "url": "https://www.ebi.ac.uk/interpro/entry/IPR000961", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR001849", "url": "https://www.ebi.ac.uk/interpro/entry/IPR001849", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR008271", "url": "https://www.ebi.ac.uk/interpro/entry/IPR008271", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR011009", "url": "https://www.ebi.ac.uk/interpro/entry/IPR011009", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR011993", "url": "https://www.ebi.ac.uk/interpro/entry/IPR011993", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR016137", "url": "https://www.ebi.ac.uk/interpro/entry/IPR016137", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR017441", "url": "https://www.ebi.ac.uk/interpro/entry/IPR017441", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR036305", "url": "https://www.ebi.ac.uk/interpro/entry/IPR036305", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR044926", "url": "https://www.ebi.ac.uk/interpro/entry/IPR044926", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "bta:282136", "url": "https://www.genome.jp/dbget-bin/www_bget?bta:282136", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "LHTHTHD", "url": "https://omabrowser.org/oma/group/LHTHTHD/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "A0A3Q1LVI8", "url": "https://www.orthodb.org/?gene=A0A3Q1LVI8", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "P26818", "url": "https://www.orthodb.org/?gene=P26818", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR24355", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR24355", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR24355:SF17", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR24355:SF17", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00069", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00069", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF00169", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00169", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF00615", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00615", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "R-BTA-418555", "url": "https://www.reactome.org/PathwayBrowser/#R-BTA-418555", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "R-BTA-8856825", "url": "https://www.reactome.org/PathwayBrowser/#R-BTA-8856825", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "NP_776925", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_776925", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "12008", "url": "https://www.rhea-db.org/rhea/12008", "database": "Rhea", "categories": [ "Enzyme and Pathway" ] }, { "id": "19429", "url": "https://www.rhea-db.org/rhea/19429", "database": "Rhea", "categories": [ "Enzyme and Pathway" ] }, { "id": "A0A3Q1LVI8", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1LVI8", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A3Q1LVI8-1", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1LVI8-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0AAA9T431", "url": "https://www.uniprot.org/uniprotkb/A0AAA9T431", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0AAA9T431-1", "url": "https://www.uniprot.org/uniprotkb/A0AAA9T431-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0AAA9TEN2", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TEN2", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0AAA9TEN2-1", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TEN2-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0AAF6YGR0", "url": "https://www.uniprot.org/uniprotkb/A0AAF6YGR0", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0AAF6YGR0-1", "url": "https://www.uniprot.org/uniprotkb/A0AAF6YGR0-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "P26818", "url": "https://www.uniprot.org/uniprotkb/P26818", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "P26818-1", "url": "https://www.uniprot.org/uniprotkb/P26818-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MADLEAVLADVSYLMAMEKSKATPAARASKKIVLPEPSIRSVMQKYLEERHEITFDKIFNQRIGFLLFKDFCLNEINEAVPQVKFYEEIKEYEKLENEEDRLCRSRQIYDTYIMKELLSCSHPFSKQAVEHVQSHLSKKQVTSTLFQPYIEEICESLRGSIFQKFMESDKFTRFCQWKNVELNIHLTMNDFSVHRIIGRGGFGEVYGCRKADTGKMYAMKCLDKKRIKMKQGETLALNERIMLSLVSTGDCPFIVCMTYAFHTPDKLCFILDLMNGGDLHYHLSQHGVFSEKEMRFYATEIILGLEHMHNRFVVYRDLKPANILLDEHGHVRISDLGLACDFSKKKPHASVGTHGYMAPEVLQKGTAYDSSADWFSLGCMLFKLLRGHSPFRQHKTKDKHEIDRMTLTMNVELPDVFSPELKSLLEGLLQRDVSKRLGCHGGSAQELKTHDFFRGIDWQHVYLQKYPPPLIPPRGEVNAADAFDIGSFDEEDTKGIKLLDCDQELYKNFPLVISERWQQEVAETVYEAVNADTDKIEARKRAKNKQLGHEEDYALGRDCIVHGYMLKLGNPFLTQWQRRYFYLFPNRLEWRGEGESRQSLLTMEQIVSVEETQIKDKKCILLRIKGGKQFVLQCESDPEFVQWKKELTETFMEAQRLLRRAPKFLNKSRSAVVELSKPPLCHRNSNGL", "length": 688, "header": "sp|P26818-1|GRK3_BOVIN Isoform 1 of G protein-coupled receptor kinase 3 OS=Bos taurus OX=9913 GN=GRK3 PE=1 SV=1 CANONICAL=P26818-1" }, "isoforms": [ { "isoform_ac": "A0A3Q1LVI8-1", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1LVI8/entry", "sequence": { "sequence": "MADLEAVLADVSYLMAMEKSKATPAARASKKIVLPEPSIRSVMQKYLEERHEITFDKIFNQRIGFLLFKDFCLNEINEAVPQVKFYEEIKEYEKLENEEDRLCRSRQIYDTYIMKELLSCSHPFSKQAVEHVQSHLSKKQVTSTLFQLTMNDFSVHRIIGRGGFGEVYGCRKADTGKMYAMKCLDKKRIKMKQGETLALNERIMLSLVSTGDCPFIVCMTYAFHTPDKLCFILDLMNGGDLHYHLSQHGVFSEKEMRFYATEIILGLEHMHNRFVVYRDLKPANILLDEHGHVRISDLGLACDFSKKKPHASVGTHGYMAPEVLQKGTAYDSSADWFSLGCMLFKLLRGHSPFRQHKTKDKHEIDRMTLTMNVELPDVFSPELKSLLEGLLQRDVSKRLGCHGGSAQELKTHDFFRGIDWQHVYLQKYPPPLIPPRGEVNAADAFDIGSFDEEDTKGIKLLDCDQELYKNFPLVISERWQQEVAETVYEAVNADTDKIEARKRAKNKQLGHEEDYALGRDCIVHGYMLKLGNPFLTQWQRRYFYLFPNRLEWRGEGESRQSLLTMEQIVSVEETQIKDKKCILLRIKGGKQFVLQCESDPEFVQWKKELTETFMEAQRLLRRAPKFLNKSRSAVVELSKPPLCHRNSNGL", "length": 650, "header": "tr|A0A3Q1LVI8-1|A0A3Q1LVI8_BOVIN Computationally mapped isoform of G protein-coupled receptor kinase OS=Bos taurus OX=9913 GN=GRK3 PE=3 SV=2 CANONICAL=P26818-1" }, "locus": { "chromosome": "17", "start_pos": 65504653, "end_pos": 65389791, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000068309.3", "url": "https://www.ensembl.org/id/ENSBTAT00000068309.3" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000059323.2", "url": "https://www.ensembl.org/id/ENSBTAP00000059323.2" } ] } }, { "isoform_ac": "A0AAA9T431-1", "url": "https://www.uniprot.org/uniprotkb/A0AAA9T431/entry", "sequence": { "sequence": "MQCSFLLFKDFCLNEINEAVPQVKFYEEIKEYEKLENEEDRLCRSRQIYDTYIMKELLSCSHPFSKQAVEHVQSHLSKKQVTSTLFQPYIEEICESLRGSIFQKFMESDKFTRFCQWKNVELNIHLTMNDFSVHRIIGRGGFGEVYGCRKADTGKMYAMKCLDKKRIKMKQGETLALNERIMLSLVSTGDCPFIVCMTYAFHTPDKLCFILDLMNGGDLHYHLSQHGVFSEKEMRFYATEIILGLEHMHNRFVVYRDLKPANILLDEHGHVRISDLGLACDFSKKKPHASVGTHGYMAPEVLQKGTAYDSSADWFSLGCMLFKLLRGHSPFRQHKTKDKHEIDRMTLTMNVELPDVFSPELKSLLEGLLQRDVSKRLGCHGGSAQELKTHDFFRGIDWQHVYLQKYPPPLIPPRGEVNAADAFDIGSFDEEDTKGIKLLDCDQELYKNFPLVISERWQQEVAETVYEAVNADTDKIEARKRAKNKQLGHEEDYALGRDCIVHGYMLKLGNPFLTQWQRRYFYLFPNRLEWRGEGESRQSLLTMEQIVSVEETQIKDKKCILLRIKGGKQFVLQCESDPEFVQWKKELTETFMEAQRLLRRAPKFLNKSRSAVVELSKPPLCHRNSNGL", "length": 628, "header": "tr|A0AAA9T431-1|GRK3_BOVIN Computationally mapped isoform of G protein-coupled receptor kinase 3 OS=Bos taurus OX=9913 GN=GRK3 PE=1 SV=1 CANONICAL=P26818-1" }, "locus": { "chromosome": "17", "start_pos": 65504653, "end_pos": 65434536, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000089301.2", "url": "https://www.ensembl.org/id/ENSBTAT00000089301.2" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000092550.1", "url": "https://www.ensembl.org/id/ENSBTAP00000092550.1" } ] } }, { "isoform_ac": "A0AAA9TEN2-1", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TEN2/entry", "sequence": { "sequence": "MLCHLTLLGADSASCQGSIGKSGPSSETDREQLFLWDLRNRIRSVMQKYLEERHEITFDKIFNQRIGFLLFKDFCLNEINEAVPQVKFYEEIKEYEKLENEEDRLCRSRQIYDTYIMKELLSCSHPFSKQAVEHVQSHLSKKQVTSTLFQPYIEEICESLRGSIFQKFMESDKFTRFCQWKNVELNIHLTMNDFSVHRIIGRGGFGEVYGCRKADTGKMYAMKCLDKKRIKMKQGETLALNERIMLSLVSTGDCPFIVCMTYAFHTPDKLCFILDLMNGGDLHYHLSQHGVFSEKEMRFYATEIILGLEHMHNRFVVYRDLKPANILLDEHGHVRISDLGLACDFSKKKPHASVGTHGYMAPEVLQKGTAYDSSADWFSLGCMLFKLLRGHSPFRQHKTKDKHEIDRMTLTMNVELPDVFSPELKSLLEGLLQRDVSKRLGCHGGSAQELKTHDFFRGIDWQHVYLQKYPPPLIPPRGEVNAADAFDIGSFDEEDTKGIKLLDCDQELYKNFPLVISERWQQEVAETVYEAVNADTDKIEARKRAKNKQLGHEEDYALGRDCIVHGYMLKLGNPFLTQWQRRYFYLFPNRLEWRGEGESRQSLLTMEQIVSVEETQIKDKKCILLRIKGGKQFVLQCESDPEFVQWKKELTETFMEAQRLLRRAPKFLNKSRSAVVELSKPPLCHRNSNGL", "length": 691, "header": "tr|A0AAA9TEN2-1|GRK3_BOVIN Computationally mapped isoform of G protein-coupled receptor kinase 3 OS=Bos taurus OX=9913 GN=GRK3 PE=1 SV=1 CANONICAL=P26818-1" }, "locus": { "chromosome": "17", "start_pos": 65504653, "end_pos": 65395107, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000113174.2", "url": "https://www.ensembl.org/id/ENSBTAT00000113174.2" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000095261.1", "url": "https://www.ensembl.org/id/ENSBTAP00000095261.1" } ] } }, { "isoform_ac": "A0AAF6YGR0-1", "url": "https://www.uniprot.org/uniprotkb/A0AAF6YGR0/entry", "sequence": { "sequence": "MADLEAVLADVSYLMAMEKSKATPAARASKKIVLPEPSIRSVMQKYLEERHEITFDKIFNQRIGFLLFKDFCLNEINEAVPQVKFYEEIKEYEKLENEEDRLCRSRQIYDTYIMKELLSCSHPFSKQAVEHVQSHLSKKQVTSTLFQPYIEEICESLRGSIFQKFMESDKFTRFCQWKNVELNIHVQSCNKHDDISYWPAVACFYGFESDESGLEGGLTMNDFSVHRIIGRGGFGEVYGCRKADTGKMYAMKCLDKKRIKMKQGETLALNERIMLSLVSTGDCPFIVCMTYAFHTPDKLCFILDLMNGGDLHYHLSQHGVFSEKEMRFYATEIILGLEHMHNRFVVYRDLKPANILLDEHGHVRISDLGLACDFSKKKPHASVGTHGYMAPEVLQKGTAYDSSADWFSLGCMLFKLLRGHSPFRQHKTKDKHEIDRMTLTMNVELPDVFSPELKSLLEGLLQRDVSKRLGCHGGSAQELKTHDFFRGIDWQHVYLQKYPPPLIPPRGEVNAADAFDIGSFDEEDTKGIKLLDCDQELYKNFPLVISERWQQEVAETVYEAVNADTDKIEARKRAKNKQLGHEEDYALGRDCIVHGYMLKLGNPFLTQWQRRYFYLFPNRLEWRGEGESRQSLLTMEQIVSVEETQIKDKKCILLRIKGGKQFVLQCESDPEFVQWKKELTETFMEAQRLLRRAPKFLNKSRSAVVELSKPPLCHRNSNGL", "length": 720, "header": "tr|A0AAF6YGR0-1|A0AAF6YGR0_BOVIN Computationally mapped isoform of G protein-coupled receptor kinase OS=Bos taurus OX=9913 GN=GRK3 PE=3 SV=1 CANONICAL=P26818-1" }, "locus": { "chromosome": "17", "start_pos": 65504653, "end_pos": 65389791, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000000005.8", "url": "https://www.ensembl.org/id/ENSBTAT00000000005.8" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000000005.7", "url": "https://www.ensembl.org/id/ENSBTAP00000000005.7" } ] } }, { "isoform_ac": "P26818-1", "url": "https://www.uniprot.org/uniprotkb/P26818/entry#P26818-1", "sequence": { "sequence": "MADLEAVLADVSYLMAMEKSKATPAARASKKIVLPEPSIRSVMQKYLEERHEITFDKIFNQRIGFLLFKDFCLNEINEAVPQVKFYEEIKEYEKLENEEDRLCRSRQIYDTYIMKELLSCSHPFSKQAVEHVQSHLSKKQVTSTLFQPYIEEICESLRGSIFQKFMESDKFTRFCQWKNVELNIHLTMNDFSVHRIIGRGGFGEVYGCRKADTGKMYAMKCLDKKRIKMKQGETLALNERIMLSLVSTGDCPFIVCMTYAFHTPDKLCFILDLMNGGDLHYHLSQHGVFSEKEMRFYATEIILGLEHMHNRFVVYRDLKPANILLDEHGHVRISDLGLACDFSKKKPHASVGTHGYMAPEVLQKGTAYDSSADWFSLGCMLFKLLRGHSPFRQHKTKDKHEIDRMTLTMNVELPDVFSPELKSLLEGLLQRDVSKRLGCHGGSAQELKTHDFFRGIDWQHVYLQKYPPPLIPPRGEVNAADAFDIGSFDEEDTKGIKLLDCDQELYKNFPLVISERWQQEVAETVYEAVNADTDKIEARKRAKNKQLGHEEDYALGRDCIVHGYMLKLGNPFLTQWQRRYFYLFPNRLEWRGEGESRQSLLTMEQIVSVEETQIKDKKCILLRIKGGKQFVLQCESDPEFVQWKKELTETFMEAQRLLRRAPKFLNKSRSAVVELSKPPLCHRNSNGL", "length": 688, "header": "sp|P26818-1|GRK3_BOVIN Isoform 1 of G protein-coupled receptor kinase 3 OS=Bos taurus OX=9913 GN=GRK3 PE=1 SV=1 CANONICAL=P26818-1" }, "locus": {} } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [ "enzyme" ], "publication": [ { "title": "Ligand-induced phosphorylation of anaphylatoxin receptors C3aR and C5aR is mediated by `G protein-coupled receptor kinases.", "journal": "European journal of immunology", "date": "1999-09", "authors": "Langkabel P, Zwirner J, Oppermann M", "evidence": [ { "database": "UniProtKB", "id": "P26818", "url": "https://www.uniprot.org/uniprotkb/P26818" } ], "reference": [ { "type": "PubMed", "id": "10508278", "url": "https://glygen.org/publication/PubMed/10508278" } ] }, { "title": "Cloning, expression, and chromosomal localization of beta-adrenergic receptor kinase 2. A new member of the receptor kinase family.", "journal": "J. Biol. Chem.", "date": "1991", "authors": "Benovic J L, Onorato J J, Arriza J L, Stone W C, Lohse M, Jenkins N A, Gilbert D J, Copeland N G, Caron M G, Lefkowitz R J", "evidence": [ { "database": "UniProtKB", "id": "P26818", "url": "https://www.uniprot.org/uniprotkb/P26818" } ], "reference": [ { "type": "PubMed", "id": "1869533", "url": "https://glygen.org/publication/PubMed/1869533" } ] }, { "title": "The c-terminus of GRK3 indicates rapid dissociation of G protein heterotrimers.", "journal": "Cellular signalling", "date": "2009", "authors": "Hollins B, Kuravi S, Digby GJ, Lambert NA", "evidence": [ { "database": "RefSeq", "id": "NP_776925", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_776925" } ], "reference": [ { "type": "PubMed", "id": "19258039", "url": "https://glygen.org/publication/PubMed/19258039" } ] } ], "pathway": [ { "id": "bta:282136", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?bta:282136", "resource": "KEGG Pathway" }, { "id": "R-BTA-418555", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-BTA-418555", "resource": "Reactome", "description": "G alpha (s) signalling events" }, { "id": "R-BTA-8856825", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-BTA-8856825", "resource": "Reactome", "description": "Cargo recognition for clathrin-mediated endocytosis" } ], "orthologs": [ { "uniprot_canonical_ac": "A0A2R8QPB8-1", "protein_name": "G protein-coupled receptor kinase", "gene_name": "grk3", "tax_id": 7955, "organism": "Danio rerio", "sequence": { "sequence": "MADLEAVLADVSYLMAMEKSKSTPAARASKKIILPEPSIRSVMQKYLEERDELAFDKIFNQKIGFLLFKDFCMNEIDEAVPQLKFYEEIKEYEKLDSEEERLTRSRQIYDVYIMKELLSCSHPFSKKAVDHVQTHLAKKQVPPNLFQPYIVEICDSLRGNIFQKFIESDKFTRFCQWKNVELNIHLTMNDFSVHRIIGRGGFGEVYGCRKADTGKMYAMKCLDKKRIKMKQGETLALNERIMLSLVSTGDCPFIVCMTYAFHTPDKLCFILDLMNGGDLHYHLSQHGVFSEKDMRFYAAEIILGLEHMHNRFVVYRDLKPANILLDEHGHVRISDLGLACDFSKKKPHASVGTHGYMAPEVLQKGTAYDSSADWFSLGCMLFKLLRGHSPFRQHKTKDKHEIDRMTLTMNVELPDSFTPELKSLLEGLLQRDVAKRLGCLGRGASEVKEHVFFKGIDWQQVYLQKYPPPLIPPRGEVNAADAFDIGSFDEEDTKGIKLLDSDQELYKNFPLVISERWQQEVAETVYEAVNSDTDKNEARKRAKNKQQGHEEDYALGKDCIMHGYMLKLGNPFLTQWQRRYFYLFPNRVEWRGEGESRECWTKTLKKHKFKQNLLTMEHIVTVEETQIKDKKCILLRVKGGKQFVLQCESDPEFVQWKKELTEAFTEAQKLLRRAPKVIGKGRTNVVELSKPPLTHRNSNGL", "length": 701 }, "evidence": [ { "id": "P26818", "url": "https://omabrowser.org/oma/group/P26818/", "database": "OMA" } ], "glygen_name": "Zebrafish", "common_name": "Zebrafish" }, { "uniprot_canonical_ac": "A0A8V0ZH32-1", "protein_name": "G protein-coupled receptor kinase", "gene_name": "MYO18B", "tax_id": 9031, "organism": "Gallus gallus", "sequence": { "sequence": "MADLEAVLADVSYLMAMEKSKSTPAARASKKITLPEPSIRSVMQKYLEERGELTFDKIFHQKIGFLLFKDYCMNEIDEAVPQLKFYEEIKEYEKLDSEEERLSRSRQIYDTYIMKELLSCSHPFSKQAVDHVQTHLSKKQVPASLFQPYIEEICDSLRGKIFQKFMESDKFTRFCQWKNVELNIHLTMNDFSVHRIIGRGGFGEVYGCRKADTGKMYAMKCLDKKRIKMKQGETLALNERIMLSLVSTGDCPFIVCMTYAFHTPDKLCFILDLMNGGDLHYHLSQHGVFSEKEMRFYATEIILGLEHMHNRFVVYRDLKPANILLDEHGHVRISDLGLACDFSKKKPHASVGTHGYMAPEVLQKGTAYDSSADWFSLGCMLFKLLRGHSPFRQHKTKDKHEIDRMTLTVNVELPDSFSPELKSLLEGLLQRDVSKRLGCQGRSAQEVKEHPFFKGIDWQQVYLQKYPPPLIPPRGEVNAADAFDIGSFDEEDTKGIKLLDSDQELYKNFPLVISERWQQEVAETVYDAVNADTDKIEARKRAKNKQLGHEEDYALGKDCIMHGYMLKLGNPFLTQWQRRYFYLFPNRLEWRGEGESRQNLLTMEQILSVEETQIKDKKCILLRIKGGKQFVLQCESDPEFVQWKKELTEAFTEAQRLLRRAPKFLNKSRSTVVELSKPPLSHRNSNGL", "length": 688 }, "evidence": [ { "id": "P26818", "url": "https://omabrowser.org/oma/group/P26818/", "database": "OMA" } ], "glygen_name": "Chicken", "common_name": "Chicken" }, { "uniprot_canonical_ac": "P26819-1", "protein_name": "G protein-coupled receptor kinase 3", "gene_name": "Grk3", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MADLEAVLADVSYLMAMEKSKATPAARASKKVVLPEPSIRSVMQRYLAERNEITFDKIFNQKIGFLLFKDFCLNEIGEAVPQVKFYEEIKEYEKLDNEEDRLHRSRQMYDAYIMRELLSSTHQFSKQAVEHVQSHLSKKQVTPTLFQPYIEEICESLRGDIFQKFMESEKFTRFCQWKNVELNIHLSMNDFSVHRIIGRGGFGEVYGCRKADTGKMYAMKCLDKKRVKMKQGETLALNERIMLSLVSTGDCPFIVCMTYAFHTPDKLCFILDLMNGGDMHYHLSQHGVFSEKEMRFYASEIILGLEHMHTCFVVYRDLKPANILLDEYGHVRISDLGLACDFSKKKPHASVGTHGYMAPEVLQKGTCYDSSADWFSLGCMLFKLLRGHSPFRQHKTKDKHEIDRMTLTVNVQLPDAFSPELRSLLEGLLQRDVSQRLGCYGGGARELKEHIFFKGIDWQYVYLRKYPPPLIPPRGEVNAADAFDIGSFDEEDTKGIKLLDCDQDLYKNFPLMISERWQQEVVETIYDAVNAETDKIEARKKAKNKQLCQEEDYAMGKDCIMHGYMLKLGNPFLTQWQRRYFYLFPNRLEWRGEGESRQNLLTMEQIMSVEETQIKDRKCILLRVKGGKQFVLQCESDPEFAQWLKELTCTFNEAQRLLRRAPKFLNKPRAAILEFSKPPLCHRNSSGL", "length": 688 }, "evidence": [ { "id": "P26818", "url": "https://omabrowser.org/oma/group/P26818/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "P32865-1", "protein_name": "G protein-coupled receptor kinase 1", "gene_name": "Gprk1", "tax_id": 7227, "organism": "Drosophila melanogaster", "sequence": { "sequence": "MADLEAVLADVSYLMAMEKSKCTPAARASKKLNLPDPSVRSVMYKYLEKEGELNFHKIFNEVLGYLLFKDFCENDSEEPIQQLKFFEQIKLFEKTECYDERKKMARDIYDNFIMEEMLSHTYEYSKHAVASVQKYLLKNEVPVDLFEPYLEEIFTQLKGKPFKKFLESDKFTRFCQWKNLELNIQLTMNDFSVHRIIGRGGFGEVYGCRKADTGKMYAMKCLDKKRIKMKQGEMLALNERNMLQAVSTGIDCPFIVCMTYAFHTPDKLCFILDLMNGGDLHYHLSQHGIFSEDEMKFYAAEVILGLEHMHKRCIVYRDLKPANILLDENGHIRISDLGLACDFSKKKPHASVGTHGYMAPEVLSKGTSYDSCADWFSFGCMLYKLLKGHSPFRQHKTKDKLEIDKMTLTMNVELPESFSLELKNLLEMLLQRDVSKRLGCMGNGADEVKMHNFFCGIDWHQVYIQKYTPPLVPPRGEVNAADAFDIGSFDEEDTKGIKLNDADQDLYKMFSLTISERWQQEVSETVFDTVNTETDKLEQKRKLKQKQHFDADEKESDCILHGYIKKLGGSFASLWQTKYAKLYPNRLELHSESGNNKPELIFMDQVEDISSDFILHKNENCIQIRINDGTRDGRIILTNSDEIGLKEWSSSLRSAHKISQDLLGSMAKKAGKIYGSERDVNKSMYIFGGNCSTKTSNGSN", "length": 700 }, "evidence": [ { "id": "P26818", "url": "https://omabrowser.org/oma/group/P26818/", "database": "OMA" } ], "glygen_name": "Fruit fly", "common_name": "Fruit fly" }, { "uniprot_canonical_ac": "P35626-1", "protein_name": "G protein-coupled receptor kinase 3", "gene_name": "GRK3", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MADLEAVLADVSYLMAMEKSKATPAARASKRIVLPEPSIRSVMQKYLAERNEITFDKIFNQKIGFLLFKDFCLNEINEAVPQVKFYEEIKEYEKLDNEEDRLCRSRQIYDAYIMKELLSCSHPFSKQAVEHVQSHLSKKQVTSTLFQPYIEEICESLRGDIFQKFMESDKFTRFCQWKNVELNIHLTMNEFSVHRIIGRGGFGEVYGCRKADTGKMYAMKCLDKKRIKMKQGETLALNERIMLSLVSTGDCPFIVCMTYAFHTPDKLCFILDLMNGGDLHYHLSQHGVFSEKEMRFYATEIILGLEHMHNRFVVYRDLKPANILLDEHGHARISDLGLACDFSKKKPHASVGTHGYMAPEVLQKGTAYDSSADWFSLGCMLFKLLRGHSPFRQHKTKDKHEIDRMTLTVNVELPDTFSPELKSLLEGLLQRDVSKRLGCHGGGSQEVKEHSFFKGVDWQHVYLQKYPPPLIPPRGEVNAADAFDIGSFDEEDTKGIKLLDCDQELYKNFPLVISERWQQEVTETVYEAVNADTDKIEARKRAKNKQLGHEEDYALGKDCIMHGYMLKLGNPFLTQWQRRYFYLFPNRLEWRGEGESRQNLLTMEQILSVEETQIKDKKCILFRIKGGKQFVLQCESDPEFVQWKKELNETFKEAQRLLRRAPKFLNKPRSGTVELPKPSLCHRNSNGL", "length": 688 }, "evidence": [ { "id": "P26818", "url": "https://omabrowser.org/oma/group/P26818/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "Q3UYH7-1", "protein_name": "G protein-coupled receptor kinase 3", "gene_name": "Grk3", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MADLEAVLADVSYLMAMEKSKTAPAARASKKVVLPEPSIRSVMQRYLAERNEITFDKIFNQKIGFLLFKDFCLNEIGEAVPQVKFYEEIKEYEKLDNEEDRLRRSRQMYDAYIMRELLSSTHQFSKQAVEHVQSHLSKKQVTATLFQPYIEEICESLRGDIFQKFMESDKFTRFCQWKNVELNIHLSMNDFSVHRIIGRGGFGEVYGCRKADTGKMYAMKCLDKKRVKMKQGETLALNERIMLSLVSTGDCPFIVCMTYAFHTPDKLCFILDLMNGGDMHYHLSQHGVFSEKEMRFYASEIILGLEHMHTCFVVYRDLKPANILLDEYGHVRISDLGLACDFSKKKPHASVGTHGYMAPEVLQKGTCYDSSADWFSLGCMLFKLLRGHSPFRQHKTKDKHEIDRMTLTVNVQLPDAFSPELRSLLEGLLQRDVSQRLGCGGGGARELKEHIFFKGIDWQHVYLRKYPPPLIPPRGEVNAADAFDIGSFDEEDTKGIKLLDCDQDLYKNFPLVISERWQQEVVETIYDAVNADTDKIEARRKAKNKQLGQEEDYAMGKDCIMHGYMLKLGNPFLTQWQRRYFYLFPNRLEWRGEGESRQSLLTMEQIMSVEETQIKDRKCILLRIKGGKQFVLQCESDPEFAQWLKELTCTFNEAQRLLRRAPKFLNKPRAAILEFSKPPLCHRNSSGL", "length": 688 }, "evidence": [ { "id": "P26818", "url": "https://omabrowser.org/oma/group/P26818/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" } ], "go_annotation": { "categories": [ { "name": "Molecular Function", "total": 4, "go_terms": [ { "name": "ATP binding", "id": "GO:0005524", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005524", "evidence": [ { "database": "UniProtKB", "id": "P26818", "url": "https://www.uniprot.org/uniprotkb/P26818" } ], "pmid": "" }, { "name": "G protein-coupled receptor binding", "id": "GO:0001664", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0001664", "evidence": [ { "database": "UniProtKB", "id": "P26818", "url": "https://www.uniprot.org/uniprotkb/P26818" } ], "pmid": "" }, { "name": "G protein-coupled receptor kinase activity", "id": "GO:0004703", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0004703", "evidence": [ { "database": "UniProtKB", "id": "P26818", "url": "https://www.uniprot.org/uniprotkb/P26818" } ], "pmid": "" }, { "name": "beta-adrenergic receptor kinase activity", "id": "GO:0047696", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0047696", "evidence": [ { "database": "UniProtKB", "id": "P26818", "url": "https://www.uniprot.org/uniprotkb/P26818" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 4, "go_terms": [ { "name": "G protein-coupled receptor signaling pathway", "id": "GO:0007186", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007186", "evidence": [ { "database": "UniProtKB", "id": "P26818", "url": "https://www.uniprot.org/uniprotkb/P26818" } ], "pmid": "" }, { "name": "desensitization of G protein-coupled receptor signaling pathway", "id": "GO:0002029", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0002029", "evidence": [ { "database": "UniProtKB", "id": "P26818", "url": "https://www.uniprot.org/uniprotkb/P26818" } ], "pmid": "" }, { "name": "signal transduction", "id": "GO:0007165", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007165", "evidence": [ { "database": "UniProtKB", "id": "P26818", "url": "https://www.uniprot.org/uniprotkb/P26818" } ], "pmid": "" }, { "name": "receptor internalization", "id": "GO:0031623", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0031623", "evidence": [ { "database": "UniProtKB", "id": "P26818", "url": "https://www.uniprot.org/uniprotkb/P26818" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 2, "go_terms": [ { "name": "postsynapse", "id": "GO:0098794", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0098794", "evidence": [ { "database": "UniProtKB", "id": "P26818", "url": "https://www.uniprot.org/uniprotkb/P26818" } ], "pmid": "" }, { "name": "presynapse", "id": "GO:0098793", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0098793", "evidence": [ { "database": "UniProtKB", "id": "P26818", "url": "https://www.uniprot.org/uniprotkb/P26818" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 666, "end_pos": 668, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [ { "id": "12008", "name": "", "equation": "[G protein-coupled receptor] + ATP = [G protein-coupled receptor]-phosphate + ADP + H(+)", "summary": "", "cellular_location": "", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [ "P43249-1", "A0A3Q1MYX1-1", "A0AAA9SDA7-1", "P21146-1", "P26818-1" ], "evidence": [ { "id": "12008", "database": "Rhea", "url": "https://www.rhea-db.org/rhea/12008" } ] }, { "id": "19429", "name": "", "equation": "[beta-adrenergic receptor] + ATP = [beta-adrenergic receptor]-phosphate + ADP + H(+)", "summary": "", "cellular_location": "", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [ "P26818-1", "P21146-1" ], "evidence": [ { "id": "19429", "database": "Rhea", "url": "https://www.rhea-db.org/rhea/19429" } ] }, { "id": "R-BTA-8851797", "name": "ADRB2 in ADRB2:GRK complex is phosphorylated", "equation": "", "summary": "This event has been computationally inferred from an event that has been demonstrated in another species.

The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.

More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "cellular_location": "cytosol, plasma membrane", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [ "P21146-1", "P43249-1", "P26818-1", "A0AAA9SDA7-1" ], "evidence": [ { "id": "R-BTA-8851797", "database": "Reactome", "url": "https://www.reactome.org/PathwayBrowser/#R-BTA-8851797" } ] }, { "id": "R-BTA-8866268", "name": "ADBRK1,2 phosphorylate AVPR2", "equation": "", "summary": "This event has been computationally inferred from an event that has been demonstrated in another species.

The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.

More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "cellular_location": "plasma membrane", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [ "P21146-1", "P26818-1" ], "evidence": [ { "id": "R-BTA-8866268", "database": "Reactome", "url": "https://www.reactome.org/PathwayBrowser/#R-BTA-8866268" } ] }, { "id": "R-BTA-8982641", "name": "ADRB2:GRK complex dissociates to Phosphorylated ADRB2", "equation": "", "summary": "This event has been computationally inferred from an event that has been demonstrated in another species.

The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.

More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "cellular_location": "cytosol, plasma membrane", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [ "P21146-1", "P43249-1", "P26818-1", "A0AAA9SDA7-1" ], "evidence": [ { "id": "R-BTA-8982641", "database": "Reactome", "url": "https://www.reactome.org/PathwayBrowser/#R-BTA-8982641" } ] }, { "id": "R-BTA-8982645", "name": "GRKs bind ADRB2:Catecholamine", "equation": "", "summary": "This event has been computationally inferred from an event that has been demonstrated in another species.

The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.

More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "cellular_location": "plasma membrane", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [ "P21146-1", "P43249-1", "P26818-1", "A0AAA9SDA7-1" ], "evidence": [ { "id": "R-BTA-8982645", "database": "Reactome", "url": "https://www.reactome.org/PathwayBrowser/#R-BTA-8982645" } ] } ], "reaction_participants": [], "reaction_enzymes": [ { "uniprot_ac": "A0A3Q1MYX1", "gene_name": "GRK4", "activity": [ { "ec_number": "2.7.11.-", "activity": "", "evidence": [ { "id": "A0A3Q1MYX1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1MYX1" } ] } ] }, { "uniprot_ac": "A0AAA9SDA7", "gene_name": "GRK6", "activity": [ { "ec_number": "2.7.11.-", "activity": "", "evidence": [ { "id": "A0AAA9SDA7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9SDA7" } ] } ] }, { "uniprot_ac": "P21146", "gene_name": "GRK2", "activity": [ { "ec_number": "2.7.11.15", "activity": "[beta-adrenergic receptor] + ATP = [beta-adrenergic receptor]-phosphate + ADP + H(+).", "evidence": [ { "id": "P21146", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P21146" } ] }, { "ec_number": "2.7.11.16", "activity": "[G-protein-coupled receptor] + ATP = [G-protein-coupled receptor]-phosphate + ADP + H(+).", "evidence": [ { "id": "P21146", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P21146" } ] }, { "ec_number": "2.7.11.16", "activity": "", "evidence": [ { "id": "P21146", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P21146" } ] } ] }, { "uniprot_ac": "P26818", "gene_name": "GRK3", "activity": [ { "ec_number": "2.7.11.-", "activity": "", "evidence": [ { "id": "P26818", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P26818" } ] }, { "ec_number": "2.7.11.15", "activity": "[beta-adrenergic receptor] + ATP = [beta-adrenergic receptor]-phosphate + ADP + H(+).", "evidence": [ { "id": "P26818", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P26818" } ] }, { "ec_number": "2.7.11.16", "activity": "[G-protein-coupled receptor] + ATP = [G-protein-coupled receptor]-phosphate + ADP + H(+).", "evidence": [ { "id": "P26818", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P26818" } ] }, { "ec_number": "2.7.11.16", "activity": "", "evidence": [ { "id": "P26818", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P26818" } ] } ] }, { "uniprot_ac": "P43249", "gene_name": "GRK5", "activity": [ { "ec_number": "2.7.11.-", "activity": "", "evidence": [ { "id": "P43249", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P43249" } ] }, { "ec_number": "2.7.11.16", "activity": "[G-protein-coupled receptor] + ATP = [G-protein-coupled receptor]-phosphate + ADP + H(+).", "evidence": [ { "id": "P43249", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P43249" } ] }, { "ec_number": "2.7.11.16", "activity": "", "evidence": [ { "id": "P43249", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P43249" } ] } ] } ], "biomarkers": [], "structures": [ { "pdb_id": "AF-P26818-F1", "pdb_chain": "global", "start_pos": 1, "end_pos": 688, "overlap": "1.0", "method": "AlphaFold", "type": "alphafold", "resolution": -1.0, "url": "https://data.glygen.org/ln2downloads/pdb/current/AF-P26818-F1.pdb", "url_external": "https://alphafold.ebi.ac.uk/entry/P26818" } ], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "P26818", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P26818" }, { "id": "PRU00618", "database": "PROSITE", "url": "https://prosite.expasy.org/PRU00618" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "AGC-kinase C-terminal", "eco_id": "ECO_0000255", "start_pos": 454, "end_pos": 521, "start_aa": "Arg", "end_aa": "Val", "glycosite_overlap": [] }, { "evidence": [ { "id": "P26818", "database": "UniProtKB", "url": 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"https://www.uniprot.org/uniprotkb/A0AAA9T5J8", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0AAA9T5J8-1", "url": "https://www.uniprot.org/uniprotkb/A0AAA9T5J8-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0AAA9TSS3", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TSS3", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0AAA9TSS3-1", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TSS3-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0AAF6YTL0", "url": "https://www.uniprot.org/uniprotkb/A0AAF6YTL0", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0AAF6YTL0-1", "url": "https://www.uniprot.org/uniprotkb/A0AAF6YTL0-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "P11242", "url": "https://www.uniprot.org/uniprotkb/P11242", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "P11242-1", "url": "https://www.uniprot.org/uniprotkb/P11242-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MPRGSVLLLASLLLAAALSATLGLGSPVKEKRGWTLNSAGYLLGPHALDSHRSFQDKHGLAGKRELEPEDEARPGSFDRPLAENNVVRTIIEFLTFLHLKDAGALERLPSLPTAESAEDAERS", "length": 123, "header": "sp|P11242-1|GALA_BOVIN Isoform 1 of Galanin peptides OS=Bos taurus OX=9913 GN=GAL PE=1 SV=1 CANONICAL=P11242-1" }, "isoforms": [ { "isoform_ac": "A0A3Q1MFV2-1", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1MFV2/entry", "sequence": { "sequence": "MPRGSVLLLASLLLAAALSATLGLGSPMLTSQAAMVKEKRGWTLNSAGYLLGPHALDSHRSFQDKHGLAGKRELEPEDEARPGSFDRPLAENNVVRTIIEFLTFLHLKDAGALERLPSLPTAESAEDAERS", "length": 131, "header": "tr|A0A3Q1MFV2-1|A0A3Q1MFV2_BOVIN Computationally mapped isoform of Galanin peptides OS=Bos taurus OX=9913 GN=GAL PE=3 SV=2 CANONICAL=P11242-1" }, "locus": { "chromosome": "29", "start_pos": 46109935, "end_pos": 46104692, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000074127.2", "url": "https://www.ensembl.org/id/ENSBTAT00000074127.2" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000069416.2", "url": "https://www.ensembl.org/id/ENSBTAP00000069416.2" } ] } }, { "isoform_ac": "A0AAA9S2M5-1", "url": "https://www.uniprot.org/uniprotkb/A0AAA9S2M5/entry", "sequence": { "sequence": "EAIHLRQLFVRIPYDFAPCCRQHRKQQHENVCAAEAGLSLEAPGGLLTRRALVIPLHCGPRTPWEAASVCACPGLEATWCIRPGSRRPWRRSSPSPRRAPDALDSHRSFQDKHGLAGKRELEPEDEARPGSFDRPLAENNVVRTIIEFLTFLHLKDAGALERLPSLPTAESAEDAERS", "length": 178, "header": "tr|A0AAA9S2M5-1|GALA_BOVIN Computationally mapped isoform of Galanin peptides OS=Bos taurus OX=9913 GN=GAL PE=1 SV=1 CANONICAL=P11242-1" }, "locus": { "chromosome": "29", "start_pos": 46109935, "end_pos": 46107247, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000094046.1", "url": "https://www.ensembl.org/id/ENSBTAT00000094046.1" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000080172.1", "url": "https://www.ensembl.org/id/ENSBTAP00000080172.1" } ] } }, { "isoform_ac": "A0AAA9T5J8-1", "url": "https://www.uniprot.org/uniprotkb/A0AAA9T5J8/entry", "sequence": { "sequence": "MPRGSVLLLASLLLAAALSATLGLGSPVKEKRGWTLNSAGYLLGPHALDSHRSFQDKHGLAGKRELEPEDEARPGERTLIPGRTGQWGYWPPTTPNPQPSLSWAPQNLSAARTRHPKPERSFDRPLAENNVVRTIIEFLTFLHLKDAGALERLPSLPTAESAEDAERS", "length": 168, "header": "tr|A0AAA9T5J8-1|GALA_BOVIN Computationally mapped isoform of Galanin peptides OS=Bos taurus OX=9913 GN=GAL PE=1 SV=1 CANONICAL=P11242-1" }, "locus": { "chromosome": "29", "start_pos": 46109935, "end_pos": 46104692, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000118592.1", "url": "https://www.ensembl.org/id/ENSBTAT00000118592.1" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000093098.1", "url": "https://www.ensembl.org/id/ENSBTAP00000093098.1" } ] } }, { "isoform_ac": "A0AAA9TSS3-1", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TSS3/entry", "sequence": { "sequence": "MAGVSEEMLARILRAAASPSTKSPWLWTTKWGPCEPEVKEKRGWTLNSAGYLLGPHALDSHRSFQDKHGLAGKRELEPEDEARPGSFDRPLAENNVVRTIIEFLTFLHLKDAGALERLPSLPTAESAEDAERS", "length": 133, "header": "tr|A0AAA9TSS3-1|GALA_BOVIN Computationally mapped isoform of Galanin peptides OS=Bos taurus OX=9913 GN=GAL PE=1 SV=1 CANONICAL=P11242-1" }, "locus": { "chromosome": "29", "start_pos": 46109935, "end_pos": 46105002, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000103065.1", "url": "https://www.ensembl.org/id/ENSBTAT00000103065.1" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000101658.1", "url": "https://www.ensembl.org/id/ENSBTAP00000101658.1" } ] } }, { "isoform_ac": "A0AAF6YTL0-1", "url": "https://www.uniprot.org/uniprotkb/A0AAF6YTL0/entry", "sequence": { "sequence": "HVEGARPPCASRFRVPEAAPCGERPRPCPTRLDGRAAPPTQDLQTPQDPQTSPDPPGPAQDAQRLRPAARLPAPRSGPFSHPGPRVTDALDSHRSFQDKHGLAGKRELEPEDEARPGSFDRPLAENNVVRTIIEFLTFLHLKDAGALERLPSLPTAESAEDAERS", "length": 165, "header": "tr|A0AAF6YTL0-1|A0AAF6YTL0_BOVIN Computationally mapped isoform of Galanin peptides OS=Bos taurus OX=9913 GN=GAL PE=3 SV=1 CANONICAL=P11242-1" }, "locus": { "chromosome": "29", "start_pos": 46109935, "end_pos": 46104259, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000012362.6", "url": "https://www.ensembl.org/id/ENSBTAT00000012362.6" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000012362.5", "url": "https://www.ensembl.org/id/ENSBTAP00000012362.5" } ] } }, { "isoform_ac": "P11242-1", "url": "https://www.uniprot.org/uniprotkb/P11242/entry#P11242-1", "sequence": { "sequence": "MPRGSVLLLASLLLAAALSATLGLGSPVKEKRGWTLNSAGYLLGPHALDSHRSFQDKHGLAGKRELEPEDEARPGSFDRPLAENNVVRTIIEFLTFLHLKDAGALERLPSLPTAESAEDAERS", "length": 123, "header": "sp|P11242-1|GALA_BOVIN Isoform 1 of Galanin peptides OS=Bos taurus OX=9913 GN=GAL PE=1 SV=1 CANONICAL=P11242-1" }, "locus": {} } ], "glycosylation": [], "phosphorylation": [ { "start_pos": 116, "end_pos": 116, "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "residue": "Ser", "comment": "Phosphoserine", "evidence": [ { "database": "UniProtKB", "id": "P11242", "url": "https://www.uniprot.org/uniprotkb/P11242" } ], "site_lbl": "Ser116" } ], "glycation": [], "keywords": [], "publication": [ { "title": "Differential activation of enkephalin, galanin, somatostatin, NPY, and VIP neuropeptide production by stimulators of protein kinases A and C in neuroendocrine chromaffin cells.", "journal": "Neuropeptides", "date": "2008", "authors": "Hook Vivian, Toneff Thomas, Baylon Sheley, Sei Catherine", "evidence": [ { "database": "RefSeq", "id": "NP_776339", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_776339" } ], "reference": [ { "type": "PubMed", "id": "18619673", "url": "https://glygen.org/publication/PubMed/18619673" } ] }, { "title": "Nucleotide sequence analysis of cDNAs encoding a bovine galanin precursor protein in the adrenal medulla and chemical isolation of bovine gut galanin.", "journal": "FEBS letters", "date": "1988-07-18", "authors": "R\u00f6kaeus A, Carlquist M", "evidence": [ { "database": "UniProtKB", "id": "P11242", "url": "https://www.uniprot.org/uniprotkb/P11242" } ], "reference": [ { "type": "PubMed", "id": "2455659", "url": "https://glygen.org/publication/PubMed/2455659" } ] }, { "title": "Identification of a TPA-responsive element mediating preferential transactivation of the galanin gene promoter in chromaffin cells.", "journal": "J. Biol. Chem.", "date": "1994", "authors": "Anouar Y, MacArthur L, Cohen J, Iacangelo A L, Eiden L E", "evidence": [ { "database": "UniProtKB", "id": "P11242", "url": "https://www.uniprot.org/uniprotkb/P11242" } ], "reference": [ { "type": "PubMed", "id": "7509811", "url": "https://glygen.org/publication/PubMed/7509811" } ] } ], "pathway": [ { "id": "bta:280799", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?bta:280799", "resource": "KEGG Pathway" }, { "id": "R-BTA-375276", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-BTA-375276", "resource": "Reactome", "description": "Peptide ligand-binding receptors" }, { "id": "R-BTA-418594", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-BTA-418594", "resource": "Reactome", "description": "G alpha (i) signalling events" } ], "orthologs": [ { "uniprot_canonical_ac": "A0A8D1G966-1", "protein_name": "Galanin peptides", "gene_name": "GAL", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MPRGCALLLASLLLAAALSATLGLGSPVKEKRGWTLNSAGYLLGPHAIDNHRSFHDKYGLAGKRELEPEDEARPGGFDRLQSEDKAIRTIMEFLAFLHLKEAGALGRLPGLPSAASSEDAGQS", "length": 123 }, "evidence": [ { "id": "P11242", "url": "https://omabrowser.org/oma/group/P11242/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "A0A9J7K651-1", "protein_name": "Galanin peptides", "gene_name": "Gal", "tax_id": 10029, "organism": "Cricetulus griseus", "sequence": { "sequence": "MARGSALLLAWLLLAATLSATLGLGVPAKEKRGWTLNSAGYLLGPHAIDNHRSFSDKHGLTGKRELQLEAEEGRPGSVDGPLPESNIVRTIMEFLSFLHLKEAGALDSLPGLPLATSSEDLEQS", "length": 124 }, "evidence": [ { "id": "P11242", "url": "https://omabrowser.org/oma/group/P11242/", "database": "OMA" } ], "glygen_name": "Hamster", "common_name": "Chinese hamster" }, { "uniprot_canonical_ac": "E7EZ53-1", "protein_name": "Galanin peptides", "gene_name": "gal", "tax_id": 7955, "organism": "Danio rerio", "sequence": { "sequence": "MHRCVGGVCVSLIVCAFLTETLGMVIAAKEKRGWTLNSAGYLLGPHAIDSHRSLSDKHGLAGKREMPLDEDFKTGALRIADEDVVHTIIDFLSYLKLKEIGALDSLPSSLTSEEISQP", "length": 118 }, "evidence": [ { "id": "P11242", "url": "https://omabrowser.org/oma/group/P11242/", "database": "OMA" } ], "glygen_name": "Zebrafish", "common_name": "Zebrafish" }, { "uniprot_canonical_ac": "P10683-1", "protein_name": "Galanin peptides", "gene_name": "Gal", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MARGSVILLAWLLLVATLSATLGLGMPTKEKRGWTLNSAGYLLGPHAIDNHRSFSDKHGLTGKRELPLEVEEGRLGSVAVPLPESNIVRTIMEFLSFLHLKEAGALDSLPGIPLATSSEDLEQS", "length": 124 }, "evidence": [ { "id": "P11242", "url": "https://omabrowser.org/oma/group/P11242/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "P22466-1", "protein_name": "Galanin peptides", "gene_name": "GAL", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MARGSALLLASLLLAAALSASAGLWSPAKEKRGWTLNSAGYLLGPHAVGNHRSFSDKNGLTSKRELRPEDDMKPGSFDRSIPENNIMRTIIEFLSFLHLKEAGALDRLLDLPAAASSEDIERS", "length": 123 }, "evidence": [ { "id": "P11242", "url": "https://omabrowser.org/oma/group/P11242/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "P47212-1", "protein_name": "Galanin peptides", "gene_name": "Gal", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MARGSVILLGWLLLVVTLSATLGLGMPAKEKRGWTLNSAGYLLGPHAIDNHRSFSDKHGLTGKRELQLEVEERRPGSVDVPLPESNIVRTIMEFLSFLHLKEAGALDSLPGIPLATSSEDLEKS", "length": 124 }, "evidence": [ { "id": "P11242", "url": "https://omabrowser.org/oma/group/P11242/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" } ], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 3, "go_terms": [ { "name": "extracellular space", "id": "GO:0005615", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005615", "evidence": [ { "database": "UniProtKB", "id": "P11242", "url": "https://www.uniprot.org/uniprotkb/P11242" } ], "pmid": "" }, { "name": "secretory granule", "id": "GO:0030141", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030141", "evidence": [ { "database": "UniProtKB", "id": "P11242", "url": "https://www.uniprot.org/uniprotkb/P11242" } ], "pmid": "" }, { "name": "extracellular region", "id": "GO:0005576", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005576", "evidence": [ { "database": "UniProtKB", "id": "P11242", "url": "https://www.uniprot.org/uniprotkb/P11242" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 2, "go_terms": [ { "name": "neuropeptide signaling pathway", "id": "GO:0007218", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007218", "evidence": [ { "database": "UniProtKB", "id": "P11242", "url": "https://www.uniprot.org/uniprotkb/P11242" } ], "pmid": "" }, { "name": "positive regulation of transcription by RNA polymerase II", "id": "GO:0045944", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0045944", "evidence": [ { "database": "UniProtKB", "id": "P11242", "url": "https://www.uniprot.org/uniprotkb/P11242" } ], "pmid": "" } ] }, { "name": "Molecular Function", "total": 7, "go_terms": [ { "name": "neuropeptide hormone activity", "id": "GO:0005184", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005184", "evidence": [ { "database": "UniProtKB", "id": "P11242", "url": "https://www.uniprot.org/uniprotkb/P11242" } ], "pmid": "" }, { "name": "galanin receptor binding", "id": "GO:0031763", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0031763", "evidence": [ { "database": "UniProtKB", "id": "P11242", "url": "https://www.uniprot.org/uniprotkb/P11242" } ], "pmid": "" }, { "name": "galanin receptor activity", "id": "GO:0004966", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0004966", "evidence": [ { "database": "UniProtKB", "id": "P11242", "url": "https://www.uniprot.org/uniprotkb/P11242" } ], "pmid": "" }, { "name": "type 1 galanin receptor binding", "id": "GO:0031764", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0031764", "evidence": [ { "database": "UniProtKB", "id": "P11242", "url": "https://www.uniprot.org/uniprotkb/P11242" } ], "pmid": "" }, { "name": "type 2 galanin receptor binding", "id": "GO:0031765", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0031765", "evidence": [ { "database": "UniProtKB", "id": "P11242", "url": "https://www.uniprot.org/uniprotkb/P11242" } ], "pmid": "" }, { "name": "type 3 galanin receptor binding", "id": "GO:0031766", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0031766", "evidence": [ { "database": "UniProtKB", "id": "P11242", "url": "https://www.uniprot.org/uniprotkb/P11242" } ], "pmid": "" }, { "name": "hormone activity", "id": "GO:0005179", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005179", "evidence": [ { "database": "UniProtKB", "id": "P11242", "url": "https://www.uniprot.org/uniprotkb/P11242" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [], 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"count": 3 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ], "tool_support": { "graph_view": "yes" } }, { "uniprot_canonical_ac": "Q17Q97-1", "uniprot_ac": "Q17Q97", "uniprot_id": "REX1B_BOVIN", "mass": { "chemical_mass": 20106.0, "monoisotopic_mass": 20106.0 }, "refseq": { "ac": "NP_001068958", "name": "required for excision 1-B domain-containing protein", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001068958" }, "gene_names": [ { "name": "REX1BD", "type": "recommended", "evidence": [ { "id": "Q17Q97", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q17Q97" } ] }, { "name": "C19orf60", "type": "synonym", "evidence": [ { "id": "NP_001068958", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001068958" } ] }, { "name": "C7H19orf60", "type": "synonym", "evidence": [ { "id": "NP_001068958", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001068958" } ] }, { "name": "REX1BD", "type": 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"id": "Q17Q97", "url": "https://www.uniprot.org/uniprotkb/Q17Q97" } ], "common_name": "Bovine", "glygen_name": "Bovine", "reference_species": "Bos taurus [9913]" } ], "gene": [ { "name": "REX1BD", "url": "https://www.uniprot.org/uniprotkb/Q17Q97", "locus": { "chromosome": "7", "start_pos": 4598864, "end_pos": 4602133, "strand": "+", "evidence": [ { "database": "Ensembl Gene", "id": "ENSBTAG00000007739", "url": "https://www.ensembl.org/id/ENSBTAG00000007739" } ] } } ], "crossref": [ { "id": "Q17Q97", "url": "https://alphafold.ebi.ac.uk/entry/Q17Q97", "database": "AlphaFoldDB", "categories": [] }, { "id": "ENSBTAG00000007739", "url": "https://bgee.org/?page=gene&gene_id=ENSBTAG00000007739", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "511085", "url": "https://www.ncbi.nlm.nih.gov/gene/511085", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR039491", "url": "https://www.ebi.ac.uk/interpro/entry/IPR039491", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "bta:511085", "url": "https://www.genome.jp/dbget-bin/www_bget?bta:511085", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "VQGLRAW", "url": "https://omabrowser.org/oma/group/VQGLRAW/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "A0A3Q1LYE1", "url": "https://www.orthodb.org/?gene=A0A3Q1LYE1", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "Q17Q97", "url": "https://www.orthodb.org/?gene=Q17Q97", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR28309", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR28309", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR28309:SF1", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR28309:SF1", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF14966", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF14966", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "NP_001068958", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001068958", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A3Q1LYE1", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1LYE1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A3Q1LYE1-1", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1LYE1-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0AAA9TR00", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TR00", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0AAA9TR00-1", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TR00-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0AAF6ZCI3", "url": "https://www.uniprot.org/uniprotkb/A0AAF6ZCI3", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0AAF6ZCI3-1", "url": "https://www.uniprot.org/uniprotkb/A0AAF6ZCI3-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "Q17Q97", "url": "https://www.uniprot.org/uniprotkb/Q17Q97", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "Q17Q97-1", "url": "https://www.uniprot.org/uniprotkb/Q17Q97-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MITAEAASESTVPAVPGDTAATGVPEHEELVWPWKDAPIRELVQRIHQLQAERAQAFRRLEEGHRQYLSSGPPYDFPRYRSTVHEVTQVFAAASREVLAVEAELAGPRAQPLLASHVRSLQQLEETRLTTVALLQLMGTPELTGQEDSLQMHQLKMKVIKTMEAISEVLQDLRFDAESAE", "length": 180, "header": "sp|Q17Q97-1|REX1B_BOVIN Isoform 1 of Required for excision 1-B domain-containing protein OS=Bos taurus OX=9913 GN=REX1BD PE=2 SV=1 CANONICAL=Q17Q97-1" }, "isoforms": [ { "isoform_ac": "A0A3Q1LYE1-1", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1LYE1/entry", "sequence": { "sequence": "MITAEAASESTVPAVPGDTAATGVPEHEELVWPWKDAPIRELVQRIHQLQAERAQAFRRLEEGHRQYLSSGPPYDFPRYRSTVHEVTQVFAAASREVLAVEAELAGPRAQPLLASHVRSLQQLEETRLTTVALLQLMGTPELTGQEDSLQMHQLKMNSHPLL", "length": 162, "header": "tr|A0A3Q1LYE1-1|REX1B_BOVIN Computationally mapped isoform of Required for excision 1-B domain-containing protein OS=Bos taurus OX=9913 GN=REX1BD PE=2 SV=2 CANONICAL=Q17Q97-1" }, "locus": { "chromosome": "7", "start_pos": 4602129, "end_pos": 4599713, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000084688.2", "url": "https://www.ensembl.org/id/ENSBTAT00000084688.2" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000062591.2", "url": "https://www.ensembl.org/id/ENSBTAP00000062591.2" } ] } }, { "isoform_ac": "A0AAA9TR00-1", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TR00/entry", "sequence": { "sequence": "MITAEAASESTVPAVPGDTAATGVPEHEELVWPWKDAPIRELVQRIHQLQAERAQAFRRLEEGHRQYLSSGPPYDFPRYRSTVHEVTQVFAAASREVLAVEAELAGPRAQPLLASHVRSLQQLEETRLTTVRPRPPAVSPAPTLRLVSPGAWPTVHPLGEGPHSVPANPAPGAPAVPSTCPS", "length": 182, "header": "tr|A0AAA9TR00-1|REX1B_BOVIN Computationally mapped isoform of Required for excision 1-B domain-containing protein OS=Bos taurus OX=9913 GN=REX1BD PE=2 SV=1 CANONICAL=Q17Q97-1" }, "locus": { "chromosome": "7", "start_pos": 4602129, "end_pos": 4601197, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000110473.1", "url": "https://www.ensembl.org/id/ENSBTAT00000110473.1" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000100793.1", "url": "https://www.ensembl.org/id/ENSBTAP00000100793.1" } ] } }, { "isoform_ac": "A0AAF6ZCI3-1", "url": "https://www.uniprot.org/uniprotkb/A0AAF6ZCI3/entry", "sequence": { "sequence": "MITAEAASESTVPAVPGDTAATGVPEHEELVWPWKDAPIRELVQRIHQLQAERAQAFRRLEERSMRVQGLRAGRSLRTLTCRRGHRQYLSSGPPYDFPRYRSTVHEVTQVFAAASREVLAVEAELAGPRAQPLLASHVRSLQQLEETRLTTVALLQLMGTPELTGQEDSLQMHQLKMKVIKTMEAISEVLQDLRFDAESAE", "length": 201, "header": "tr|A0AAF6ZCI3-1|A0AAF6ZCI3_BOVIN Computationally mapped isoform of Required for excision 1-B domain containing OS=Bos taurus OX=9913 GN=REX1BD PE=4 SV=1 CANONICAL=Q17Q97-1" }, "locus": { "chromosome": "7", "start_pos": 4602129, "end_pos": 4599640, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000036534.4", "url": "https://www.ensembl.org/id/ENSBTAT00000036534.4" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000036391.4", "url": "https://www.ensembl.org/id/ENSBTAP00000036391.4" } ] } }, { "isoform_ac": "Q17Q97-1", "url": "https://www.uniprot.org/uniprotkb/Q17Q97/entry#Q17Q97-1", "sequence": { "sequence": "MITAEAASESTVPAVPGDTAATGVPEHEELVWPWKDAPIRELVQRIHQLQAERAQAFRRLEEGHRQYLSSGPPYDFPRYRSTVHEVTQVFAAASREVLAVEAELAGPRAQPLLASHVRSLQQLEETRLTTVALLQLMGTPELTGQEDSLQMHQLKMKVIKTMEAISEVLQDLRFDAESAE", "length": 180, "header": "sp|Q17Q97-1|REX1B_BOVIN Isoform 1 of Required for excision 1-B domain-containing protein OS=Bos taurus OX=9913 GN=REX1BD PE=2 SV=1 CANONICAL=Q17Q97-1" }, "locus": {} } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [ { "id": "bta:511085", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?bta:511085", "resource": "KEGG Pathway" } ], "orthologs": [ { "uniprot_canonical_ac": "A0A8I6AA43-1", "protein_name": "Required for excision 1-B domain containing", "gene_name": "Rex1bd", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MLTAATEVLAAADGPGSAEPTWAWRDAPIATLVQRIQQLQNERAQAFRRLDQAHRQYLLSDLHHDFPSYRSVVHEVTQAFAAASCEVLAVEAELAGPRAQPVLARHVRNLQELEQTRLATVRSPPLLQNGAWATTHSQPPRPTTIFATHLGAFGPSPGFSCLPVFPSQILLIYTSPSVKLP", "length": 181 }, "evidence": [ { "id": "Q17Q97", "url": "https://omabrowser.org/oma/group/Q17Q97/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "B8JL57-1", "protein_name": "Required for excision 1-B domain-containing protein", "gene_name": "rex1bd", "tax_id": 7955, "organism": "Danio rerio", "sequence": { "sequence": "MLQCSFISKPMKTPKACFSTMAPSDFKSLVRRFYVLQSERVEAYKLFEEGHEAYLRTGPHYDFEHYKQLVHEITKAFCGISKEVLTIKQQLHQDFDRPDLSEHIDKLQIKEKEKLELTAKLQLTRQSAQDHPEDEDFQEKVREIKQEIIKNTAALSEILQDFKFDSEEPE", "length": 170 }, "evidence": [ { "id": "Q17Q97", "url": "https://omabrowser.org/oma/group/Q17Q97/", "database": "OMA" } ], "glygen_name": "Zebrafish", "common_name": "Zebrafish" }, { "uniprot_canonical_ac": "G3H492-1", "protein_name": "Required for excision 1-B domain-containing protein isoform X1", "gene_name": "Rex1bd", "tax_id": 10029, "organism": "Cricetulus griseus", "sequence": { "sequence": "MLTATAEVPAAVDAPASTEPAWAWRDAPISTLVQRIQQLQNERAQAFRRLDQAHRQYLLSGQHHDFPSYRSVVHEVTQAFAAASREVLAVEAELAGPRAQPVLARHVRSLQDLEQTRLATVALLQVMGTPGVSEQEDPEKLHQLKIKVIKTMEAISEVLQELRFDAESAE", "length": 170 }, "evidence": [ { "id": "Q17Q97", "url": "https://omabrowser.org/oma/group/Q17Q97/", "database": "OMA" } ], "glygen_name": "Hamster", "common_name": "Chinese hamster" }, { "uniprot_canonical_ac": "Q96EN9-1", "protein_name": "Required for excision 1-B domain-containing protein", "gene_name": "REX1BD", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MITETAAEPTVPAVPAAEEATEARGREEPAWPWKDAPIRTLVQRIHQLQAERAQGFRRLEEWLAPVQGLRAWGRGLRVPTCRRGHRQYLRSGPDYDFARYRSTVHGVTQAFAAASREVLAVEAELGGPRRQPLLAGHVRSLQELEQTRLGTVALLQLMETPELAGQEDAVRMQQLKMKVIKTMEAISEVLQDLRFDAESAE", "length": 201 }, "evidence": [ { "id": "Q17Q97", "url": "https://omabrowser.org/oma/group/Q17Q97/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "Q9CYZ6-1", "protein_name": "Required for excision 1-B domain-containing protein", "gene_name": "Rex1bd", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MLTAATEVLAAADGPGSAESAWAWRDAPIATLVQRIQQLQNERAQAFRRLDQAHRQYLLSGQHYDFPSYRSVVHEVTQAFAAASREVLAVEAELAGPRAQPVLARHVRSLQELEQTRLATVALLQVMGTPGVSEQDPEKLHQLKIKVIKTMEAIGEVLQELRFDAESAE", "length": 169 }, "evidence": [ { "id": "Q17Q97", "url": "https://omabrowser.org/oma/group/Q17Q97/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" } ], "go_annotation": {}, "pro_annotation": [], "site_annotation": [], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [ { "pdb_id": "AF-Q17Q97-F1", "pdb_chain": "global", "start_pos": 1, "end_pos": 180, "overlap": "1.0", "method": "AlphaFold", "type": "alphafold", "resolution": -1.0, "url": "https://data.glygen.org/ln2downloads/pdb/current/AF-Q17Q97-F1.pdb", "url_external": "https://alphafold.ebi.ac.uk/entry/Q17Q97" } ], "lectin_list": [], "domain_list": [], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" }, { "name": "homologset.oma", "label": "OMA Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ], "tool_support": { "graph_view": "yes" } }, { "uniprot_canonical_ac": "Q2KIB3-1", "uniprot_ac": "Q2KIB3", "uniprot_id": "TM101_BOVIN", "mass": { "chemical_mass": 28683.0, "monoisotopic_mass": 28683.0 }, "refseq": { "ac": "NP_001039667", "name": "transmembrane protein 101", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001039667" }, "gene_names": [ { "name": "TMEM101", "type": "recommended", "evidence": [ { "id": "Q2KIB3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q2KIB3" } ] }, { "name": "TMEM101", "type": "synonym", "evidence": [ { "id": "NP_001039667", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001039667" } ] } ], "protein_names": [ { "name": "Transmembrane protein 101", "type": "recommended", "evidence": [ { "id": "Q2KIB3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q2KIB3/entry#names_and_taxonomy" } ] }, { "name": "transmembrane protein 101", "type": "synonym", "evidence": [ { "id": "NP_001039667", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001039667" } ] } ], "function": [ { "annotation": "May activate NF-kappa-B signaling pathways.", "evidence": [ { "database": "UniProtKB", "id": "Q2KIB3", "url": "https://www.uniprot.org/uniprotkb/Q2KIB3#function" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Bos taurus", "taxid": 9913, "evidence": [ { "database": "UniProtKB", "id": "Q2KIB3", "url": "https://www.uniprot.org/uniprotkb/Q2KIB3" } ], "common_name": "Bovine", "glygen_name": "Bovine", "reference_species": "Bos taurus [9913]" } ], "gene": [ { "name": "TMEM101", "url": "https://www.uniprot.org/uniprotkb/Q2KIB3", "locus": { "chromosome": "19", "start_pos": 43868247, "end_pos": 43871821, "strand": "+", "evidence": [ { "database": "Ensembl Gene", "id": "ENSBTAG00000016251", "url": "https://www.ensembl.org/id/ENSBTAG00000016251" } ] } } ], "crossref": [ { "id": "Q2KIB3", "url": "https://alphafold.ebi.ac.uk/entry/Q2KIB3", "database": "AlphaFoldDB", "categories": [] }, { "id": "ENSBTAG00000016251", "url": "https://bgee.org/?page=gene&gene_id=ENSBTAG00000016251", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "515507", "url": "https://www.ncbi.nlm.nih.gov/gene/515507", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR029371", "url": "https://www.ebi.ac.uk/interpro/entry/IPR029371", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "bta:515507", "url": "https://www.genome.jp/dbget-bin/www_bget?bta:515507", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "HVEFWNQ", "url": "https://omabrowser.org/oma/group/HVEFWNQ/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "Q2KIB3", "url": "https://www.orthodb.org/?gene=Q2KIB3", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR31034", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR31034", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR31034:SF2", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR31034:SF2", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF15111", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF15111", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "NP_001039667", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001039667", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A3Q1M025", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1M025", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A3Q1M025-1", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1M025-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "Q2KIB3", "url": "https://www.uniprot.org/uniprotkb/Q2KIB3", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "Q2KIB3-1", "url": "https://www.uniprot.org/uniprotkb/Q2KIB3-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MASKTGSRRWMLQLIMQLGSVLLTRCPFWGCFSQLMLYAERAEARRKPDIPVPYLYFDMGAAVLCASFMSFGVKRRWFALGAALQLAISTYAAYVGGYVHYGDWLKVRMYSRTVAIIGGFLVLASGAGELYRRKPRSRSLQSTGQVFLGVYLVCVAYSLQHSKEDRLAYLNHLPGGELMVQLFFVLYGVLALAFLSGYYVTLAAQILAVLLPPVMLLIDGNVAYWHNTRRVEFWNQMKLLGESVGIFGAAVILATDG", "length": 257, "header": "sp|Q2KIB3-1|TM101_BOVIN Isoform 1 of Transmembrane protein 101 OS=Bos taurus OX=9913 GN=TMEM101 PE=2 SV=1 CANONICAL=Q2KIB3-1" }, "isoforms": [ { "isoform_ac": "A0A3Q1M025-1", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1M025/entry", "sequence": { "sequence": "MLRGPRRAGERVRAVAECGGGGPARPRNGGAVRWGRSCGLEVGTLGLGGTGTSDLLGTLVWSMVGIELSAGVLAMRGGSGLQKQWSLREPEESQDSSSRFILCFNSVLVPSPFPTRRKPDIPVPYLYFDMGAAVLCASFMSFGVKRRWFALGAALQLAISTYAAYVGGYVHYGDWLKVRMYSRTVAIIGGFLVLASGAGELYRRKPRSRSLQSTGQVFLGVYLVCVAYSLQHSKEDRLAYLNHLPGGELMVQLFFVLYGVLALAFLSGYYVTLAAQILAVLLPPVMLLIDGNVAYWHNTRRVEFWNQMKLLGESVGIFGAAVILATDG", "length": 328, "header": "tr|A0A3Q1M025-1|TM101_BOVIN Computationally mapped isoform of Transmembrane protein 101 OS=Bos taurus OX=9913 GN=TMEM101 PE=2 SV=1 CANONICAL=Q2KIB3-1" }, "locus": { "chromosome": "19", "start_pos": 43871622, "end_pos": 43868991, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000070254.2", "url": "https://www.ensembl.org/id/ENSBTAT00000070254.2" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000066524.1", "url": "https://www.ensembl.org/id/ENSBTAP00000066524.1" } ] } }, { "isoform_ac": "Q2KIB3-1", "url": "https://www.uniprot.org/uniprotkb/Q2KIB3/entry#Q2KIB3-1", "sequence": { "sequence": "MASKTGSRRWMLQLIMQLGSVLLTRCPFWGCFSQLMLYAERAEARRKPDIPVPYLYFDMGAAVLCASFMSFGVKRRWFALGAALQLAISTYAAYVGGYVHYGDWLKVRMYSRTVAIIGGFLVLASGAGELYRRKPRSRSLQSTGQVFLGVYLVCVAYSLQHSKEDRLAYLNHLPGGELMVQLFFVLYGVLALAFLSGYYVTLAAQILAVLLPPVMLLIDGNVAYWHNTRRVEFWNQMKLLGESVGIFGAAVILATDG", "length": 257, "header": "sp|Q2KIB3-1|TM101_BOVIN Isoform 1 of Transmembrane protein 101 OS=Bos taurus OX=9913 GN=TMEM101 PE=2 SV=1 CANONICAL=Q2KIB3-1" }, "locus": { "chromosome": "19", "start_pos": 43871734, "end_pos": 43868991, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000021619.4", "url": "https://www.ensembl.org/id/ENSBTAT00000021619.4" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000021619.3", "url": "https://www.ensembl.org/id/ENSBTAP00000021619.3" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [ { "id": "bta:515507", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?bta:515507", "resource": "KEGG Pathway" } ], "orthologs": [ { "uniprot_canonical_ac": "A0A1D5PDS8-1", "protein_name": "Transmembrane protein 101", "gene_name": "TMEM101", "tax_id": 9031, "organism": "Gallus gallus", "sequence": { "sequence": "MAAGRGWRRRALRLLTAGGGVLLTRFPFWHCFSGLLLCAERADGRRKPDIPVPYLYVDMGVAVLCASFMSFGVKRRWFALGAALQLAVATYASHIGGHVHYGDWLKVRMYSRTIAIIGGFLILASGAGELYRQKPRSRSLQSTGQVFLGIYLICQAYSLQHSKEDRLAYLNHILGGELTLQLLFVLYGLLALAFLSGYYVRVAAQVLAVLLPLAILLIDGNIGYWHEARRVEFWNQMKLIGQNVGIFGAVVILATDG", "length": 257 }, "evidence": [ { "id": "Q2KIB3", "url": "https://omabrowser.org/oma/group/Q2KIB3/", "database": "OMA" } ], "glygen_name": "Chicken", "common_name": "Chicken" }, { "uniprot_canonical_ac": "A0A2R8PYE5-1", "protein_name": "Transmembrane protein 101", "gene_name": "tmem101", "tax_id": 7955, "organism": "Danio rerio", "sequence": { "sequence": "MAAATRKKALRFFSQFGAFILTRFGFWNCFAMLMLFAERADVKRKPDIQVPYLYIDLGAAVLCASFMSFGVKRRWFALAAAIHLALSTYVSYVGGQVHYGDWLKVRMYSRAMAIIGGFLILSSGAGEVYRQKPRTRSLQSTGQVFLGIYLICMVYSLQHSKEDRLAYLDHIPGGELTVQLLVLVFGVLALAYLSGCYVRVASQILAVLLPLVILFIDGNFGYWHRSCRVEFWNQMKLIGQNVGIFGAVLILATDS", "length": 255 }, "evidence": [ { "id": "Q2KIB3", "url": "https://omabrowser.org/oma/group/Q2KIB3/", "database": "OMA" } ], "glygen_name": "Zebrafish", "common_name": "Zebrafish" }, { "uniprot_canonical_ac": "A0A8D0J2S3-1", "protein_name": "Transmembrane protein 101", "gene_name": "TMEM101", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MASKMGSRRWMLQLIMQLGSVLLTRCPFWGCFSQLMLYAERAEARRKPDIPVPYLYFDMGAAVLCASFMSFGVKRRWFALGAALQLAVSTYAAYIGGYVHYGDWLKVRMYSRTVAIIGGFLVLASGAGELYRRKPRSRSLQSTGQVFLGIYLICVAYSLQHSKEDRLAYLNHLPGGELMIQLFFVLYGVLALAFLSGYYVTLAAQILAVLLPPVMLLIDGNVAYWHSTRRVEFWNQMKLLGESVGIFGTAIILATDG", "length": 257 }, "evidence": [ { "id": "Q2KIB3", "url": "https://omabrowser.org/oma/group/Q2KIB3/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "G3HLI9-1", "protein_name": "Transmembrane protein 101 isoform X1", "gene_name": "Tmem101", "tax_id": 10029, "organism": "Cricetulus griseus", "sequence": { "sequence": "MSSKIGSRRWMLQLIMQLGSVLLTRCPFWGCFSQLMLYAERAEARRKPDIPVPYLYFDMAAAVLCASFMSFGVKRRWFALGAALQLAISTYAAYIGGYVHYGDWLKVRMYSRTVAIIGGFLVLASGAGELYRRKPRSRSLQSTGQVFLGIYLICVAYSLQHSKEDRLAYLNHLPGGELMVQMFFVLYGVLALAFLSGYYVTLAAQILAVLLPPVMLLIDGNVSYWHNTRRVEFWNQMKLLGESVGIFGAAVILATDG", "length": 257 }, "evidence": [ { "id": "Q2KIB3", "url": "https://omabrowser.org/oma/group/Q2KIB3/", "database": "OMA" } ], "glygen_name": "Hamster", "common_name": "Chinese hamster" }, { "uniprot_canonical_ac": "G3V8U1-1", "protein_name": "Transmembrane protein 101", "gene_name": "Tmem101", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MLGEVGGQKSEHLDREELVLRQIGRCSGSAVRPELMWRPQQKPDIPVPYLYFDMGAAVLCASFMSFGVKRRWFALGAALQLAISTYAAYIGGYVHYGDWLKVRMYSRTVAIIGGFLVLASGAGELYRRKPRSRSLQSTGQVFLGIYLICVAYSLQHSKEDRLAYLNHLPGGELMVQLFFVLYGVLALAFLSGYYVTLAAQILAVLLPPVMLLIDGNVSYWHNTRRVEFWNQMKLLGESVGIFGAAVILATDG", "length": 252 }, "evidence": [ { "id": "Q2KIB3", "url": "https://omabrowser.org/oma/group/Q2KIB3/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "Q91VP7-1", "protein_name": "Transmembrane protein 101", "gene_name": "Tmem101", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MASKIGSRRWMLQLIMQLGSVLLTRCPFWGCFSQLMLYAERAEARRKPDIPVPYLYFDMGAAVLCASFMSFGVKRRWFALGAALQLAISTYTAYIGGYVHYGDWLKVRMYSRTVAIIGGFLVLASGAGELYRRKPRSRSLQSTGQVFLGIYLICVAYSLQHSKEDRLAYLNHLPGGELMVQLFFVLYGVLALAFLSGYYVTLAAQILAVLLPPVMLLIDGNVSYWHNTRRVEFWNQMKLLGESVGIFGAAVILATDG", "length": 257 }, "evidence": [ { "id": "Q2KIB3", "url": "https://omabrowser.org/oma/group/Q2KIB3/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q96IK0-1", "protein_name": "Transmembrane protein 101", "gene_name": "TMEM101", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MASKIGSRRWMLQLIMQLGSVLLTRCPFWGCFSQLMLYAERAEARRKPDIPVPYLYFDMGAAVLCASFMSFGVKRRWFALGAALQLAISTYAAYIGGYVHYGDWLKVRMYSRTVAIIGGFLVLASGAGELYRRKPRSRSLQSTGQVFLGIYLICVAYSLQHSKEDRLAYLNHLPGGELMIQLFFVLYGILALAFLSGYYVTLAAQILAVLLPPVMLLIDGNVAYWHNTRRVEFWNQMKLLGESVGIFGTAVILATDG", "length": 257 }, "evidence": [ { "id": "Q2KIB3", "url": "https://omabrowser.org/oma/group/Q2KIB3/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" } ], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 1, "go_terms": [ { "name": "membrane", "id": "GO:0016020", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016020", "evidence": [ { "database": "UniProtKB", "id": "Q2KIB3", "url": "https://www.uniprot.org/uniprotkb/Q2KIB3" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [ { "pdb_id": "AF-Q2KIB3-F1", "pdb_chain": "global", "start_pos": 1, "end_pos": 257, "overlap": "1.0", "method": "AlphaFold", "type": "alphafold", "resolution": -1.0, "url": "https://data.glygen.org/ln2downloads/pdb/current/AF-Q2KIB3-F1.pdb", "url_external": "https://alphafold.ebi.ac.uk/entry/Q2KIB3" } ], "lectin_list": [], "domain_list": [], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" }, { "name": "homologset.oma", "label": "OMA Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ], "tool_support": { "graph_view": "yes" } }, { "uniprot_canonical_ac": "Q3ZCB2-1", "uniprot_ac": "Q3ZCB2", "uniprot_id": "PLAC8_BOVIN", "mass": { "chemical_mass": 12554.0, "monoisotopic_mass": 12554.0 }, "refseq": { "ac": "NP_001070455", "name": "placenta-specific gene 8 protein", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001070455" }, "gene_names": [ { "name": "PLAC8B", "type": "recommended", "evidence": [ { "id": "Q3ZCB2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q3ZCB2" } ] }, { "name": "PLAC8", "type": "recommended", "evidence": [ { "id": "Q3ZCB2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q3ZCB2" } ] }, { "name": "PLAC8B", "type": "synonym", "evidence": [ { "id": "NP_001070455", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001070455" } ] }, { "name": "PLAC8", "type": "synonym", "evidence": [ { "id": "NP_001070455", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001070455" } ] } ], "protein_names": [ { "name": "Placenta-specific gene 8 protein", "type": "recommended", "evidence": [ { "id": "Q3ZCB2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q3ZCB2/entry#names_and_taxonomy" } ] }, { "name": "placenta specific 8 B", "type": "synonym", "evidence": [ { "id": "NP_001070455", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001070455" } ] }, { "name": "placenta-specific 8", "type": "synonym", "evidence": [ { "id": "NP_001070455", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001070455" } ] }, { "name": "placenta-specific gene 8 protein", "type": "synonym", "evidence": [ { "id": "NP_001070455", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001070455" } ] } ], "function": [], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Bos taurus", "taxid": 9913, "evidence": [ { "database": "UniProtKB", "id": "Q3ZCB2", "url": "https://www.uniprot.org/uniprotkb/Q3ZCB2" } ], "common_name": "Bovine", "glygen_name": "Bovine", "reference_species": "Bos taurus [9913]" } ], "gene": [ { "name": "PLAC8", "url": "https://www.uniprot.org/uniprotkb/Q3ZCB2", "locus": {} } ], "crossref": [ { "id": "Q3ZCB2", "url": "https://alphafold.ebi.ac.uk/entry/Q3ZCB2", "database": "AlphaFoldDB", "categories": [] }, { "id": "ENSBTAG00000031750", "url": "https://bgee.org/?page=gene&gene_id=ENSBTAG00000031750", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "767910", "url": "https://www.ncbi.nlm.nih.gov/gene/767910", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR006461", "url": "https://www.ebi.ac.uk/interpro/entry/IPR006461", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "bta:767910", "url": "https://www.genome.jp/dbget-bin/www_bget?bta:767910", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "YLATLCC", "url": "https://omabrowser.org/oma/group/YLATLCC/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "Q3ZCB2", "url": "https://www.orthodb.org/?gene=Q3ZCB2", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR15907", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR15907", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF04749", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF04749", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "R-BTA-6798695", "url": "https://www.reactome.org/PathwayBrowser/#R-BTA-6798695", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "NP_001070455", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001070455", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A3Q1M2C0", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1M2C0", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A3Q1M2C0-1", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1M2C0-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "Q3ZCB2", "url": "https://www.uniprot.org/uniprotkb/Q3ZCB2", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "Q3ZCB2-1", "url": "https://www.uniprot.org/uniprotkb/Q3ZCB2-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MQAASSPVVIVTQPGVGSGPAPQNSNWQTGLCDCFSDCGVCLCGTFCFTCLACQVASDMNECCLCGTSVAMRTLYRTRYGIPGSICDDFMVTHCCPLCSLCQIKRDINRRRANRTF", "length": 116, "header": "sp|Q3ZCB2-1|PLAC8_BOVIN Isoform 1 of Placenta-specific gene 8 protein OS=Bos taurus OX=9913 GN=PLAC8 PE=3 SV=1 CANONICAL=Q3ZCB2-1" }, "isoforms": [ { "isoform_ac": "A0A3Q1M2C0-1", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1M2C0/entry", "sequence": { "sequence": "TLVLPDHPVSTLPLIQLHPHSSPSLVPATLCVTSHCQDKPSYLQRLFPLSSIYKIPNHHSIFRSSNSIFPEHWRPHFCLCGTFCFTCLACQVASDMNECCLCGTSVAMRTLYRTRYGIPGSICDDFMVTHCCPLCSLCQIKRDINRRRANRTF", "length": 153, "header": "tr|A0A3Q1M2C0-1|PLAC8_BOVIN Computationally mapped isoform of Placenta-specific gene 8 protein OS=Bos taurus OX=9913 GN=PLAC8 PE=3 SV=1 CANONICAL=Q3ZCB2-1" }, "locus": { "chromosome": "6", "start_pos": 97892450, "end_pos": 97885657, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000045018.3", "url": "https://www.ensembl.org/id/ENSBTAT00000045018.3" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000042447.2", "url": "https://www.ensembl.org/id/ENSBTAP00000042447.2" } ] } }, { "isoform_ac": "Q3ZCB2-1", "url": "https://www.uniprot.org/uniprotkb/Q3ZCB2/entry#Q3ZCB2-1", "sequence": { "sequence": "MQAASSPVVIVTQPGVGSGPAPQNSNWQTGLCDCFSDCGVCLCGTFCFTCLACQVASDMNECCLCGTSVAMRTLYRTRYGIPGSICDDFMVTHCCPLCSLCQIKRDINRRRANRTF", "length": 116, "header": "sp|Q3ZCB2-1|PLAC8_BOVIN Isoform 1 of Placenta-specific gene 8 protein OS=Bos taurus OX=9913 GN=PLAC8 PE=3 SV=1 CANONICAL=Q3ZCB2-1" }, "locus": { "chromosome": "6", "start_pos": 97893865, "end_pos": 97885657, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000069324.2", "url": "https://www.ensembl.org/id/ENSBTAT00000069324.2" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000067552.2", "url": "https://www.ensembl.org/id/ENSBTAP00000067552.2" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [ { "id": "bta:767910", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?bta:767910", "resource": "KEGG Pathway" }, { "id": "R-BTA-6798695", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-BTA-6798695", "resource": "Reactome", "description": "Neutrophil degranulation" } ], "orthologs": [ { "uniprot_canonical_ac": "A0ABK0M497-1", "protein_name": "Placenta associated 8", "gene_name": "Plac8", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MTKVKPLVDALKKKKKASLVCITFYVFVVTSNRRGIVTGSPGCLKSAPNLVFGDLELKMAQAATVIVTQPGFVRAPQNSNWQTSLCDCFSDCGVCLCGTFCFTCLGCQVAADMNECCLCGTTVAMRTLYRTRYGIPGSICDDYMVTLFCPVCSVCQIKRDINRRRAMNAF", "length": 170 }, "evidence": [ { "id": "Q3ZCB2", "url": "https://omabrowser.org/oma/group/Q3ZCB2/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "F1RVD7-1", "protein_name": "Placenta associated 8", "gene_name": "PLAC8", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "ESLSSHKTQPAQNLFLNYHSHLRSCIQNASSGSSGHCDSARRWLHPSNLQLADRLVRLLQRLRRLHNETTVPTPPKQEHANPPTPSLCGIFCFSCLAVQVASDLNECCLCGTSVAMRTLYRTRYGIPGSICDDFMVTLCCPMCSLCQIKRDINRRRAMHTF", "length": 161 }, "evidence": [ { "id": "Q3ZCB2", "url": "https://omabrowser.org/oma/group/Q3ZCB2/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "Q9NZF1-1", "protein_name": "Placenta-specific gene 8 protein", "gene_name": "PLAC8", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MQAQAPVVVVTQPGVGPGPAPQNSNWQTGMCDCFSDCGVCLCGTFCFPCLGCQVAADMNECCLCGTSVAMRTLYRTRYGIPGSICDDYMATLCCPHCTLCQIKRDINRRRAMRTF", "length": 115 }, "evidence": [ { "id": "Q3ZCB2", "url": "https://omabrowser.org/oma/group/Q3ZCB2/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" } ], "go_annotation": { "categories": [ { "name": "Biological Process", "total": 1, "go_terms": [ { "name": "positive regulation of transcription by RNA polymerase II", "id": "GO:0045944", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0045944", "evidence": [ { "database": "UniProtKB", "id": "Q3ZCB2", "url": "https://www.uniprot.org/uniprotkb/Q3ZCB2" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 113, "end_pos": 115, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [ { "pdb_id": "AF-Q3ZCB2-F1", "pdb_chain": "global", "start_pos": 1, "end_pos": 116, "overlap": "1.0", "method": "AlphaFold", "type": "alphafold", "resolution": -1.0, "url": "https://data.glygen.org/ln2downloads/pdb/current/AF-Q3ZCB2-F1.pdb", "url_external": "https://alphafold.ebi.ac.uk/entry/Q3ZCB2" } ], "lectin_list": [], "domain_list": [], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" }, { "name": "homologset.oma", "label": "OMA Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 113, "end_pos": 115 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ], "tool_support": { "graph_view": "yes" } }, { "uniprot_canonical_ac": "Q2KIR0-1", "uniprot_ac": "Q2KIR0", "uniprot_id": "SMIP2_BOVIN", "mass": { "chemical_mass": 22602.0, "monoisotopic_mass": 22602.0 }, "refseq": { "ac": "NP_001070556", "name": "protein SPMIP2", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001070556" }, "gene_names": [ { "name": "SPMIP2", "type": "recommended", "evidence": [ { "id": "Q2KIR0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q2KIR0" } ] }, { "name": "C17H4orf45", "type": "synonym", "evidence": [ { "id": "NP_001070556", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001070556" }, { "id": "Q2KIR0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q2KIR0" } ] }, { "name": "SPMIP2", "type": "synonym", "evidence": [ { "id": "NP_001070556", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001070556" } ] } ], "protein_names": [ { "name": "Protein SPMIP2", "type": "recommended", "evidence": [ { "id": "Q2KIR0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q2KIR0/entry#names_and_taxonomy" } ] }, { "name": "protein SPMIP2", "type": "synonym", "evidence": [ { "id": "NP_001070556", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001070556" } ] }, { "name": "uncharacterized protein C4orf45 homolog", "type": "synonym", "evidence": [ { "id": "NP_001070556", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001070556" } ] } ], "function": [], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Bos taurus", "taxid": 9913, "evidence": [ { "database": "UniProtKB", "id": "Q2KIR0", "url": "https://www.uniprot.org/uniprotkb/Q2KIR0" } ], "common_name": "Bovine", "glygen_name": "Bovine", "reference_species": "Bos taurus [9913]" } ], "gene": [ { "name": "SPMIP2", "url": "https://www.uniprot.org/uniprotkb/Q2KIR0", "locus": { "chromosome": "17", "start_pos": 40116757, "end_pos": 39983282, "strand": "-", "evidence": [ { "database": "Ensembl Gene", "id": "ENSBTAG00000033547", "url": "https://www.ensembl.org/id/ENSBTAG00000033547" } ] } } ], "crossref": [ { "id": "Q2KIR0", "url": "https://alphafold.ebi.ac.uk/entry/Q2KIR0", "database": "AlphaFoldDB", "categories": [] }, { "id": "ENSBTAG00000033547", "url": "https://bgee.org/?page=gene&gene_id=ENSBTAG00000033547", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "768029", "url": "https://www.ncbi.nlm.nih.gov/gene/768029", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "8OTZ", "url": "https://www.ncbi.nlm.nih.gov/Structure/icn3d/?mmdbid=8OTZ&bu=0", "database": "iCn3D", "categories": [ "3D Structure" ] }, { "id": "9FQR", "url": "https://www.ncbi.nlm.nih.gov/Structure/icn3d/?mmdbid=9FQR&bu=0", "database": "iCn3D", "categories": [ "3D Structure" ] }, { "id": "IPR027814", "url": "https://www.ebi.ac.uk/interpro/entry/IPR027814", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "bta:768029", "url": "https://www.genome.jp/dbget-bin/www_bget?bta:768029", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "DRRNSKW", "url": "https://omabrowser.org/oma/group/DRRNSKW/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "Q2KIR0", "url": "https://www.orthodb.org/?gene=Q2KIR0", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR34833", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR34833", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR34833:SF1", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR34833:SF1", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "pdb_00008otz", "url": "https://www.rcsb.org/structure/pdb_00008otz", "database": "PDB", "categories": [ "3D Structure" ] }, { "id": "pdb_00009fqr", "url": "https://www.rcsb.org/structure/pdb_00009fqr", "database": "PDB", "categories": [ "3D Structure" ] }, { "id": "8OTZ", "url": "https://www.rcsb.org/structure/8OTZ", "database": "PDB", "categories": [ "3D Structure" ] }, { "id": "9FQR", "url": "https://www.rcsb.org/structure/9FQR", "database": "PDB", "categories": [ "3D Structure" ] }, { "id": "PF15123", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF15123", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "NP_001070556", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001070556", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A3Q1M2K0", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1M2K0", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A3Q1M2K0-1", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1M2K0-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "Q2KIR0", "url": "https://www.uniprot.org/uniprotkb/Q2KIR0", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "Q2KIR0-1", "url": "https://www.uniprot.org/uniprotkb/Q2KIR0-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MACVTFREPISATVGKRMVFTGPAYVKDHLPQVAQHTAYIGEKRPALEKTGDLRYLWRPASNRSLPAKYKPEYVGEIGWGIPEYDFINKTRLQTGFHIKYEEFSQAAIDKLSHRYQSPWQPNPSIMDAEGSSSRGFIAWHMGDYEDTSQRNSKRAVLLRQSKAALPIGSRPPKLPKLPKKEEKSKFRPLHQHDARCY", "length": 197, "header": "sp|Q2KIR0-1|SMIP2_BOVIN Isoform 1 of Protein SPMIP2 OS=Bos taurus OX=9913 GN=SPMIP2 PE=1 SV=1 CANONICAL=Q2KIR0-1" }, "isoforms": [ { "isoform_ac": "A0A3Q1M2K0-1", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1M2K0/entry", "sequence": { "sequence": "MACVTFREPISATVGKRMVFTGPAYVKDHLPQVAQHTAYIGEKRPALEKTGDLRYLWRPASNRSLPAKYKPEYVGEIGWGIPEYDFINKTRLQTGFHIKYEEFSQAAIDKLSHRYQSPWQPNPSIMDAEGSSSRGFIAWHMGDYEDTSQRNSKRAVLLRQSKAALPIGSRPPKLPNHPAFQY", "length": 182, "header": "tr|A0A3Q1M2K0-1|SMIP2_BOVIN Computationally mapped isoform of Protein SPMIP2 OS=Bos taurus OX=9913 GN=SPMIP2 PE=1 SV=2 CANONICAL=Q2KIR0-1" }, "locus": { "chromosome": "17", "start_pos": 40101474, "end_pos": 39983401, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000076039.2", "url": "https://www.ensembl.org/id/ENSBTAT00000076039.2" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000064026.2", "url": "https://www.ensembl.org/id/ENSBTAP00000064026.2" } ] } }, { "isoform_ac": "Q2KIR0-1", "url": "https://www.uniprot.org/uniprotkb/Q2KIR0/entry#Q2KIR0-1", "sequence": { "sequence": "MACVTFREPISATVGKRMVFTGPAYVKDHLPQVAQHTAYIGEKRPALEKTGDLRYLWRPASNRSLPAKYKPEYVGEIGWGIPEYDFINKTRLQTGFHIKYEEFSQAAIDKLSHRYQSPWQPNPSIMDAEGSSSRGFIAWHMGDYEDTSQRNSKRAVLLRQSKAALPIGSRPPKLPKLPKKEEKSKFRPLHQHDARCY", "length": 197, "header": "sp|Q2KIR0-1|SMIP2_BOVIN Isoform 1 of Protein SPMIP2 OS=Bos taurus OX=9913 GN=SPMIP2 PE=1 SV=1 CANONICAL=Q2KIR0-1" }, "locus": { "chromosome": "17", "start_pos": 40116635, "end_pos": 39983401, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000047680.2", "url": "https://www.ensembl.org/id/ENSBTAT00000047680.2" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000044861.1", "url": "https://www.ensembl.org/id/ENSBTAP00000044861.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [ { "id": "bta:768029", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?bta:768029", "resource": "KEGG Pathway" } ], "orthologs": [ { "uniprot_canonical_ac": "A0A0G2JEB7-1", "protein_name": "Sperm microtubule inner protein 2", "gene_name": "Spmip2", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MALSHREPHCETVGKRMIVTGPDYVKDHLPKVHQHTAYIGEKRPALEKTGDLRYLWRPASNRSLPAKYKHEYTCGIGWGIPQYSFFNRSRVESGFHIQHGELSLRAMDKITHRYQNPCKQEHGPWGSSWMLVTNSAGRKISDPDKDLGGSPDLGHQQVLRGPIRPLTSVLPQAAAPPEDINKASGGSADHGPPPGLQLLTSPPDINTDSGRTTDPDRAPSSSPGVDYVSSGDSTGMSSDWYGPQRLCRPLTSIWPPPAARPRDICMISGHPHGLPLFTCSTDSDYSRTTDPDLVLSSCTVPNINMVSRGHRGYSDRYGPQRLRRPLTSIWPPAVARPKNINMDSSSSLEHGHPHGLQLLTSPKDINTDSGCSRTTDPDMALSSSMSPDTNMISGGGRGYTEWHGHLKLRSPQTPMWPQVAPQPTDVCMTSGGNTHLTVDINKDPRFSTMQCRADGAMDNTVASDGSPAQGYQPGFRLKYRLRRSAWS", "length": 487 }, "evidence": [ { "id": "Q2KIR0", "url": "https://omabrowser.org/oma/group/Q2KIR0/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q96LM5-1", "protein_name": "Protein SPMIP2", "gene_name": "SPMIP2", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MASVSYQKPTSTTVGKQMIFTGPDYIKDYLPKIHQHTSYVGEQHLALEKTGDLRYLWRPASNRSLPAKYKHEYVSEIGWRIPQYNFINKSRLGSGFHIKYEELSQASLDSITHRYQNPWQPKPHVLDMQGKQSRASFAWHMSAFEDTDQRNSKWAILVRQCKSSLPRASKPPKLPKLPKKEKKRKH", "length": 186 }, "evidence": [ { "id": "Q2KIR0", "url": "https://omabrowser.org/oma/group/Q2KIR0/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" } ], "go_annotation": {}, "pro_annotation": [], "site_annotation": [ { "start_pos": 62, "end_pos": 64, "annotation": "n_glycosylation_sequon" }, { "start_pos": 88, "end_pos": 90, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], 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[ "Gene Expression" ] }, { "id": "613945", "url": "https://www.ncbi.nlm.nih.gov/gene/613945", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR037185", "url": "https://www.ebi.ac.uk/interpro/entry/IPR037185", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR039632", "url": "https://www.ebi.ac.uk/interpro/entry/IPR039632", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "bta:613945", "url": "https://www.genome.jp/dbget-bin/www_bget?bta:613945", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "QIALWWV", "url": "https://omabrowser.org/oma/group/QIALWWV/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "A0A3Q1M2V3", "url": "https://www.orthodb.org/?gene=A0A3Q1M2V3", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "Q2KIX3", "url": "https://www.orthodb.org/?gene=Q2KIX3", "database": "OrthoDB", "categories": [ "Protein 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"MAGRPLPGGGGVCAAAYPNTSAGFPPHLQAGAMRRRFWGVFNCLCAGAFGALAAASAKLAFGREVNVGFCVLGIIMMATTNSLMWTFFSRGLSLSMSSAIASVTVTFSNILNSVRLVEDHSWVSGPRLPAPDLSSCPGRHSATGESGGAHPPCRHVSTQPHSCLCPTGLPGFCVVRRVPGGLVVGWSVPHPLWTHPDPQGAPTAQEAPSAQAAVAPAGWADPLERQSWRLRLGLACGDRSSGRSGCSAFRPWARGGCCPGKWAHDQEALWVDSSSFCQGKYSSAVFCPKPPPPSVCTVLLILMFPGPPSRPRQVQETLGLVSFLYGLETTL", "length": 331, "header": "tr|A0AAF6Z3L5-1|A0AAF6Z3L5_BOVIN Computationally mapped isoform of Transmembrane protein 42 OS=Bos taurus OX=9913 GN=TMEM42 PE=4 SV=1 CANONICAL=Q2KIX3-1" }, "locus": { "chromosome": "22", "start_pos": 54274421, "end_pos": 54271151, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000022236.5", "url": "https://www.ensembl.org/id/ENSBTAT00000022236.5" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000022236.4", "url": "https://www.ensembl.org/id/ENSBTAP00000022236.4" } ] } }, { "isoform_ac": "Q2KIX3-1", "url": "https://www.uniprot.org/uniprotkb/Q2KIX3/entry#Q2KIX3-1", "sequence": { "sequence": "MAGRPLPGGGGVCAAAYPNTSAGFPPHLQAGAMRRRFWGVFNCLCAGAFGALAAASAKLAFGREVNVGFCVLGIIMMATTNSLMWTFFSRGLSLSMSSAIASVTVTFSNILNSAFLGFVLYGECQEVLWWGGVFLILCGLTLIHRELPPPRKPLPHKQR", "length": 159, "header": "sp|Q2KIX3-1|TMM42_BOVIN Isoform 1 of Transmembrane protein 42 OS=Bos taurus OX=9913 GN=TMEM42 PE=2 SV=1 CANONICAL=Q2KIX3-1" }, "locus": {} } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [ { "id": "bta:613945", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?bta:613945", "resource": "KEGG Pathway" } ], "orthologs": [ { "uniprot_canonical_ac": "A0A287AVE9-1", "protein_name": "Transmembrane protein 42", "gene_name": "TMEM42", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MAVAGGPQVVGSGVCAASHSNVSAGFPPHLQAGAMRRRFWGVFNCLCAGAFGALAAASAKLAFGSEVNVAFCILGIIMMATTNSLMWTFFSRGLSFSMSSAIASVTVTFSNILSSAFLGFVLYGECQQVLWWGGVFLILCGLTLIHRELPPTSKALPHKQQ", "length": 161 }, "evidence": [ { "id": "Q2KIX3", "url": "https://omabrowser.org/oma/group/Q2KIX3/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "Q55FN6-1", "protein_name": "EamA domain-containing protein", "gene_name": "", "tax_id": 44689, "organism": "Dictyostelium discoideum", "sequence": { "sequence": "MKRETKKSNNEIKKSINKDNKIKNEEKKPLVNTINLKLSFIYSLIGGVFASLSSVCGKVALDSQFLSQFISSDNIELITRAISIGSIFICTTMQWRYAAKGMDLANSTLTSTVITTSSNFFFTAFFGWLFFKEQLSFKWWIGAFFIMFGLFLMNADQDKIETNQKSDKLKKKD", "length": 173 }, "evidence": [ { "id": "Q2KIX3", "url": "https://omabrowser.org/oma/group/Q2KIX3/", "database": "OMA" } ], "glygen_name": "Cellular slime mold", "common_name": "Social amoeba" }, { "uniprot_canonical_ac": "Q69YG0-1", "protein_name": "Transmembrane protein 42", "gene_name": "TMEM42", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MAERPGPPGGAVSATAYPDTPAEFPPHLQAGAMRRRFWGVFNCLCAGAFGALAAASAKLAFGSEVSMGLCVLGIIVMASTNSLMWTFFSRGLSFSMSSAIASVTVTFSNILSSAFLGYVLYGECQEVLWWGGVFLILCGLTLIHRKLPPTWKPLPHKQQ", "length": 159 }, "evidence": [ { "id": "Q2KIX3", "url": "https://omabrowser.org/oma/group/Q2KIX3/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "Q9CR22-1", "protein_name": "Transmembrane protein 42", "gene_name": "Tmem42", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MAAGPQSSGAAVSAAAYPDSPVELPARLQKGAMRRRFWGVFNCLCAGAFGALAAAAAKLAFGSQVNIGLCVLGIVAMASANSLMWTFFSRGLSFSMSSAIASVTVTFSNILCSAILGYLLYGECQEILWWGGVFLILCGLTLIHRKFPPTWKESKEQ", "length": 157 }, "evidence": [ { "id": "Q2KIX3", "url": "https://omabrowser.org/oma/group/Q2KIX3/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" } ], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 1, "go_terms": [ { "name": "membrane", "id": "GO:0016020", "url": 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"protein_names": [ { "name": "Uncharacterized protein C2orf42 homolog", "type": "recommended", "evidence": [ { "id": "Q3SYX3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q3SYX3/entry#names_and_taxonomy" } ] }, { "name": "uncharacterized protein C2orf42 homolog", "type": "synonym", "evidence": [ { "id": "NP_001029886", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001029886" } ] } ], "function": [], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Bos taurus", "taxid": 9913, "evidence": [ { "database": "UniProtKB", "id": "Q3SYX3", "url": "https://www.uniprot.org/uniprotkb/Q3SYX3" } ], "common_name": "Bovine", "glygen_name": "Bovine", "reference_species": "Bos taurus [9913]" } ], "gene": [ { "name": "", "url": "https://www.uniprot.org/uniprotkb/Q3SYX3", "locus": {} } ], "crossref": [ { "id": "Q3SYX3", "url": "https://alphafold.ebi.ac.uk/entry/Q3SYX3", "database": "AlphaFoldDB", "categories": [] }, { "id": "ENSBTAG00000016939", "url": "https://bgee.org/?page=gene&gene_id=ENSBTAG00000016939", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "540909", "url": "https://www.ncbi.nlm.nih.gov/gene/540909", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR026049", "url": "https://www.ebi.ac.uk/interpro/entry/IPR026049", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR029269", "url": "https://www.ebi.ac.uk/interpro/entry/IPR029269", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR060076", "url": "https://www.ebi.ac.uk/interpro/entry/IPR060076", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "bta:540909", "url": "https://www.genome.jp/dbget-bin/www_bget?bta:540909", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "FWMPSQL", "url": "https://omabrowser.org/oma/group/FWMPSQL/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "A0A3Q1M5W2", "url": "https://www.orthodb.org/?gene=A0A3Q1M5W2", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "Q3SYX3", "url": "https://www.orthodb.org/?gene=Q3SYX3", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR13518", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR13518", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR13518:SF1", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR13518:SF1", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF14952", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF14952", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF26708", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF26708", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "NP_001029886", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001029886", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A3Q1M5W2", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1M5W2", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A3Q1M5W2-1", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1M5W2-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "Q3SYX3", "url": "https://www.uniprot.org/uniprotkb/Q3SYX3", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "Q3SYX3-1", "url": "https://www.uniprot.org/uniprotkb/Q3SYX3-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MEPNSLRTKVPAFLSDLGKATLRGIRKCPRCGTYNGTRGLSCKNKTCGTIFRYGARKQPSVEAVKIITGSDLQVYSVRQRDRGPDYRCFVELGVSETTIQTVDGTIITQLSSGRCYVPSCLKAATQGVVENQCQHIKLAVNCQAEATPLTLKSSVLNAMQASPETKQTIWQLATEPTGPLVQRITKNILVVKCKASQKHSLGYLHTSFVQKIGAKSLPERRFFCSCQTLKSHKSNASKDEAVQRCIHFFACICAFASDETLAQEFSDFLNFDSSGLKEVIVPQLGCHSESPVSACESTASKPKKRKKEEVSGAQTNSSLLPPDTVSSNLRKSGLKKPVVASSLKRQACGQLLDEAQVTLSFQDWLASVTERIHQTMHYQFDGKPEPLVFHIPQSFFDALQQRISIGSAKKRLPNSTTAFIRKDALPLGTFSKYTWHITNILQVKQILDTPEMPLEITRSFIQNRDGTYELFKCPKVEVESIAETYGRIEKQPVLRPLELKTFLKVGNTSPDQKEPTPFIIEWIPDILPQSKIGELRIKFEYGHHRNGHVAEYQDQRPPLDQPLELAPLTTITFP", "length": 574, "header": "sp|Q3SYX3-1|CB042_BOVIN Isoform 1 of Uncharacterized protein C2orf42 homolog OS=Bos taurus OX=9913 GN= PE=2 SV=1 CANONICAL=Q3SYX3-1" }, "isoforms": [ { "isoform_ac": "A0A3Q1M5W2-1", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1M5W2/entry", "sequence": { "sequence": "MEPNSLRTKVPAFLSDLGKATLRGIRKCPRCGTYNGTRGLSCKNKTCGTIFRYGARKQPSVEAVKIITGSDLQVYSVRQRDRGPDYRCFVELGVSETTIQTVDGTIITQLSSGRCYVPSCLKAATQGVVENQCQHIKLAVNCQAEATPLTLKSSVLNAMQASPETKQTIWQLATEPTGPLVQRITKNILVVKCKASQKHSLGYLHTSFVQKIGAKSLPERRFFCSCQTLKSHKSNASKDEAVQRCIHFFACICAFASDETLAQEFSDFLNFDSSGLKEVIVPQLGCHSESPVSACESTASKPKKRKKEEVSACGQLLDEAQVTLSFQDWLASVTERIHQTMHYQFDGKPEPLVFHIPQSFFDALQQRISIGSAKKRLPNSTTAFIRKDALPLGTFSKYTWHITNILQVKQILDTPEMPLEITRSFIQNRDGTYELFKCPKVEVESIAETYGRIEKQPVLRPLELKTFLKVGNTSPDQKEPTPFIIEWIPDILPQSKIGELRIKFEYGHHRNGHVAEYQDQRPPLDQPLELAPLTTITFP", "length": 539, "header": "tr|A0A3Q1M5W2-1|CB042_BOVIN Computationally mapped isoform of Uncharacterized protein C2orf42 homolog OS=Bos taurus OX=9913 GN= PE=2 SV=1 CANONICAL=Q3SYX3-1" }, "locus": { "chromosome": "11", "start_pos": 68499320, "end_pos": 68474541, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000067665.2", "url": "https://www.ensembl.org/id/ENSBTAT00000067665.2" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000069088.1", "url": "https://www.ensembl.org/id/ENSBTAP00000069088.1" } ] } }, { "isoform_ac": "Q3SYX3-1", "url": "https://www.uniprot.org/uniprotkb/Q3SYX3/entry#Q3SYX3-1", "sequence": { "sequence": "MEPNSLRTKVPAFLSDLGKATLRGIRKCPRCGTYNGTRGLSCKNKTCGTIFRYGARKQPSVEAVKIITGSDLQVYSVRQRDRGPDYRCFVELGVSETTIQTVDGTIITQLSSGRCYVPSCLKAATQGVVENQCQHIKLAVNCQAEATPLTLKSSVLNAMQASPETKQTIWQLATEPTGPLVQRITKNILVVKCKASQKHSLGYLHTSFVQKIGAKSLPERRFFCSCQTLKSHKSNASKDEAVQRCIHFFACICAFASDETLAQEFSDFLNFDSSGLKEVIVPQLGCHSESPVSACESTASKPKKRKKEEVSGAQTNSSLLPPDTVSSNLRKSGLKKPVVASSLKRQACGQLLDEAQVTLSFQDWLASVTERIHQTMHYQFDGKPEPLVFHIPQSFFDALQQRISIGSAKKRLPNSTTAFIRKDALPLGTFSKYTWHITNILQVKQILDTPEMPLEITRSFIQNRDGTYELFKCPKVEVESIAETYGRIEKQPVLRPLELKTFLKVGNTSPDQKEPTPFIIEWIPDILPQSKIGELRIKFEYGHHRNGHVAEYQDQRPPLDQPLELAPLTTITFP", "length": 574, "header": "sp|Q3SYX3-1|CB042_BOVIN Isoform 1 of Uncharacterized protein C2orf42 homolog OS=Bos taurus OX=9913 GN= PE=2 SV=1 CANONICAL=Q3SYX3-1" }, "locus": { "chromosome": "11", "start_pos": 68499320, "end_pos": 68474541, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000022529.3", "url": "https://www.ensembl.org/id/ENSBTAT00000022529.3" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000022529.2", "url": "https://www.ensembl.org/id/ENSBTAP00000022529.2" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [ { "id": "bta:540909", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?bta:540909", "resource": "KEGG Pathway" } ], "orthologs": [ { "uniprot_canonical_ac": "A0A8C2M7F6-1", "protein_name": "Uncharacterized protein C2orf42 homolog isoform X1", "gene_name": "C8H2orf42", "tax_id": 10029, "organism": "Cricetulus griseus", "sequence": { "sequence": "MEPNSQRTKVPAFLSDLGKATLRGIRKCPRCGTYNGTRGLSCKNKTCGTIFRYGARKQPSIEAVKIITGSDLQVYSVRQRDRGPDYRCFVELGVSETTIQTVDGTIITQLSSGRCYVPSCLKAATQGIVENQCQHIKLAVNCQAEATPLTLKSSVLNAMQASPETKQTIWQLATEPTGPLVQRVTKSIMVVKCKASQKHSLGYLHTSFMQKIGSRSLPERRFFCSCQSLKSHKSNIPKAEAAPKCIHFFACLCAFASDETLAQEFSDFLNFDASGLKEVMVPQLGCHSESSVSACESAASKPRKRKKDEMSGAQVNSSLMPQDTVNSIVRKSALKKPVVASSLKRQVCGQLLDEAQVTLSFQDWLASVTERIHQTMHYQFDGKPEPLVFHIPQSFFDALQQRISIGSAKKRLPNSTTAFVRKDALPLGTFSKYTWHITNILQVKQILDTPEMPLEITRSFIQNRDGTYELFKCPKVEVESIAETYGRIEKQPVLRPLELKTFLKVGNTSPDQKEPTPFIIEWIPDILPQSKIGELRIKFEYGHHRNGHVADYQDPRPPLDQPLELAPLTTITFP", "length": 574 }, "evidence": [ { "id": "Q3SYX3", "url": "https://omabrowser.org/oma/group/Q3SYX3/", "database": "OMA" } ], "glygen_name": "Hamster", "common_name": "Chinese hamster" }, { "uniprot_canonical_ac": "F1SLC8-1", "protein_name": "Chromosome 3 C2orf42 homolog", "gene_name": "C2orf42", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MEPNSLRTKVPAFLSDLGKATLRGIRKCPRCGTYNGTRGLSCKNKTCGTIFRYGARKQPSAEAVKIITGSDLQVYSVRQRDRGPDYRCFVELGVSETTIQTVDGTIITQLSSGRCYVPSCLKAATQGVVENQCQHIKLAVNCQTEATPLTLKSSVLNAMQASPETKQTIWQLATEPTGPLVQRITKNILVVKCKASQKHSLGYLHTSFMQKISAKSLPERRFFCSCQTLKSHKSNASKDEAVQRCIHFFACICAFASDETLAQEFSDFLNFDSSGLKEIIVPQLGCHSESTVSACESTASKPKKRKKEEVSGAQTNSSMLPQDAVNSNLRKSGLKKPVVASSLKRQACGQLLDEAQVTLSFQDWLASVTERIHQTMHYQFDGKPEPLVFHIPQSFFDALQQRISIGSAKKRLPNSTTAFVRKDALPLGTFSKYTWHITNILQVKQILDTPEMPLEITRSFIQNRDGTYELFKCPKVEVESIAETYGRIEKQPVLRPLELKTFLKVGNTSPDQKEPTPFIIEWIPDILPQSKIGELRIKFEYGHHRNGHVAEYQDQRPPLDQPLELAPLTTITFP", "length": 574 }, "evidence": [ { "id": "Q3SYX3", "url": "https://omabrowser.org/oma/group/Q3SYX3/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "Q8R3C1-1", "protein_name": "Uncharacterized protein C2orf42 homolog", "gene_name": "", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MEPNSQRTKVPAFLSDLGKATLRGIRKCPRCGTFNGTRGLSCKNKTCGTIFRYGARKQPSIEAVKIITGSDLQVYSVRQRDRGPDYRCFVELGVSETAIQTVDGTIITQLSSGRCYVPSCLKAATQGIVENQCQHIKLAVTCQAEATPLTLKSSVLNALQAAPETKQSLWQLATEPTGPLVQRVTKNIMVVKCKASQKHNLGYLHASFMQKISSRSLPERRFFCSCQTLRPHKSSVPKAEAAPKCIHFFACLCAFASDETLAQEFSDFLNFDASGLKEIIVPHLGCHAESSVSACESAASKPRKRKKDEVSGAQVNSSLMPQDAVNSNLRKSGLKRPVVTSSLKRHVCGQLLDEAQVTLSFQDWLASVTERIHQTMHYQFDGKPEPLVFHIPQSFFDALQQRISIGSAKKRLPNSTTAFVRKDALPLGTFSKYTWHITNILQVKQILDTPEMPLEITRSFIQNRDGTYELFKCPKVEVENIAESYGRIEKQPVLRPLELKTFLKVGNTSPDQKEPTPFIIEWIPDILPQSKIGELRIKFEYGHHRNGHVADYQDPRPPMDQPLELAPLTTITFP", "length": 574 }, "evidence": [ { "id": "Q3SYX3", "url": "https://omabrowser.org/oma/group/Q3SYX3/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q9NWW7-1", "protein_name": "Uncharacterized protein C2orf42", "gene_name": "C2orf42", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MEPNSLRTKVPAFLSDLGKATLRGIRKCPRCGTYNGTRGLSCKNKTCGTIFRYGARKQPSVEAVKIITGSDLQVYSVRQRDRGPDYRCFVELGVSETTIQTVDGTIITQLSSGRCYVPSCLKAATQGVVENQCQHIKLAVNCQAEATPLTLKSSVLNAMQASPETKQTIWQLATEPTGPLVQRITKNILVVKCKASQKHSLGYLHTSFVQKVSGKSLPERRFFCSCQTLKSHKSNASKDETAQRCIHFFACICAFASDETLAQEFSDFLNFDSSGLKEIIVPQLGCHSESTVSACESTASKSKKRRKDEVSGAQMNSSLLPQDAVSSNLRKSGLKKPVVASSLKRQACGQLLDEAQVTLSFQDWLASVTERIHQTMHYQFDGKPEPLVFHIPQSFFDALQQRISIGSAKKRLPNSTTAFVRKDALPLGTFSKYTWHITNILQVKQILDTPEMPLEITRSFIQNRDGTYELFKCPKVEVESIAETYGRIEKQPVLRPLELKTFLKVGNTSPDQKEPTPFIIEWIPDILPQSKIGELRIKFEYGHHRNGHVAEYQDQRPPLDQPLELAPLTTITFP", "length": 574 }, "evidence": [ { "id": "Q3SYX3", "url": "https://omabrowser.org/oma/group/Q3SYX3/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "Q9VAL2-1", "protein_name": "Treble-clef zinc-finger domain-containing protein", "gene_name": "Dmel\\CG2321", "tax_id": 7227, "organism": "Drosophila melanogaster", "sequence": { "sequence": "MRGVRKCVHCGAINGNRALLCKNSECPQRRNVLDAVQLVSLRPGSTVYSLRTKEKEQQPRNFVVIQDVTLSLQPDAAVVSSKAECFVESCKRTGGEPTDCVHVKACRELGAEFAKAQVYRVSREVLWNLNISLEQKQNLWQLYKYAEEEEHLPGVQRLNHSTFAVKCERSESFPAARLHVTVSANGLSKKKSSYACACRKLKIIVEPDNSLVMQDEICDHLLLVLAGILSSPQGKRVYGHFTSGLQTFWMPLQLETPLGDVATEDLRLSLDMVDELDPQVDILVFGDQLDLSLPNLSDGVFNLDTMQAATSSQSASSTNDALIHYANDSQLLSNLDVYAEPIELTDCNIELMDQFQPTDQLDICSEDIELPLISEPYNILAAPPIFTEATPSVVADQLPIELATISMVKKAPVKFSEIVTEVKSLKQPSLPAKRELIVNGAASAASACLDASVQPALSYSAWLDHVIELLNDSCEPLETESNTLTKRLVQQNFHVHKETFSHFCKSFSTGVKRRPLDKLTVIESGKHKGLSKYTWHFASPHTAKRIFSTSNVQLQLDRAFERHAEGHFVPYVRPPMEPQVPGQPKKRIVYPRLSLYMVKILFEAAPKDYVGNGVLVTWTPDVLPRSQFGLMHVEFTVETRPPR", "length": 643 }, "evidence": [ { "id": "Q3SYX3", "url": "https://omabrowser.org/oma/group/Q3SYX3/", "database": "OMA" } ], "glygen_name": "Fruit fly", "common_name": "Fruit fly" } ], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 2, "go_terms": [ { "name": "nucleus", "id": "GO:0005634", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005634", "evidence": [ { "database": "UniProtKB", "id": "Q3SYX3", "url": "https://www.uniprot.org/uniprotkb/Q3SYX3" } ], "pmid": "" }, { "name": "nucleoplasm", "id": "GO:0005654", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005654", "evidence": [ { "database": "UniProtKB", "id": "Q3SYX3", "url": "https://www.uniprot.org/uniprotkb/Q3SYX3" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 235, "end_pos": 237, "annotation": "n_glycosylation_sequon" }, { "start_pos": 316, "end_pos": 318, "annotation": "n_glycosylation_sequon" }, { "start_pos": 35, "end_pos": 37, "annotation": "n_glycosylation_sequon" }, { "start_pos": 414, "end_pos": 416, "annotation": "n_glycosylation_sequon" }, { "start_pos": 44, "end_pos": 46, "annotation": "n_glycosylation_sequon" }, { "start_pos": 507, "end_pos": 509, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [ { "pdb_id": "AF-Q3SYX3-F1", "pdb_chain": "global", "start_pos": 1, "end_pos": 574, "overlap": "1.0", "method": "AlphaFold", "type": "alphafold", "resolution": -1.0, "url": "https://data.glygen.org/ln2downloads/pdb/current/AF-Q3SYX3-F1.pdb", "url_external": "https://alphafold.ebi.ac.uk/entry/Q3SYX3" } ], "lectin_list": [], "domain_list": [], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" }, { "name": "homologset.oma", "label": "OMA Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 235, "end_pos": 237 }, { "start_pos": 316, "end_pos": 318 }, { "start_pos": 35, "end_pos": 37 }, { "start_pos": 414, "end_pos": 416 }, { "start_pos": 44, "end_pos": 46 }, { "start_pos": 507, "end_pos": 509 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ], "tool_support": { "graph_view": "yes" } }, { "uniprot_canonical_ac": "Q3T136-1", "uniprot_ac": "Q3T136", "uniprot_id": "AT7L1_BOVIN", "mass": { "chemical_mass": 16232.0, "monoisotopic_mass": 16232.0 }, "refseq": { "ac": "NP_001030484", "name": "ataxin-7-like protein 1 isoform 2", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001030484" }, "gene_names": [ { "name": "ATXN7L1", "type": "recommended", "evidence": [ { "id": "Q3T136", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q3T136" } ] }, { "name": "ATXN7L1", "type": "synonym", "evidence": [ { "id": "NP_001030484", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001030484" } ] }, { "name": "ATXN7L4", "type": "synonym", "evidence": [ { "id": "NP_001030484", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001030484" }, { "id": "Q3T136", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q3T136" } ] } ], "protein_names": [ { "name": "Ataxin-7-like protein 1", "type": "recommended", "evidence": [ { "id": "Q3T136", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q3T136/entry#names_and_taxonomy" } ] }, { "name": "Ataxin-7-like protein 4", "type": "synonym", "evidence": [ { "id": "Q3T136", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q3T136/entry#names_and_taxonomy" } ] }, { "name": "ataxin 7-like 4", "type": "synonym", "evidence": [ { "id": "NP_001030484", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001030484" } ] }, { "name": "ataxin-7-like protein 1 isoform 2", "type": "synonym", "evidence": [ { "id": "NP_001030484", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001030484" } ] }, { "name": "ataxin-7-like protein 1", "type": "synonym", "evidence": [ { "id": "NP_001030484", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001030484" } ] }, { "name": "ataxin-7-like protein 4", "type": "synonym", "evidence": [ { "id": "NP_001030484", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001030484" } ] } ], "function": [], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Bos taurus", "taxid": 9913, "evidence": [ { "database": "UniProtKB", "id": "Q3T136", "url": "https://www.uniprot.org/uniprotkb/Q3T136" } ], "common_name": "Bovine", "glygen_name": "Bovine", "reference_species": "Bos taurus [9913]" } ], "gene": [ { "name": "ATXN7L1", "url": "https://www.uniprot.org/uniprotkb/Q3T136", "locus": { "chromosome": "4", "start_pos": 46705583, "end_pos": 46714958, "strand": "+", "evidence": [ { "database": "Ensembl Gene", "id": "ENSBTAG00000002037", "url": "https://www.ensembl.org/id/ENSBTAG00000002037" } ] } } ], "crossref": [ { "id": "Q3T136", "url": "https://alphafold.ebi.ac.uk/entry/Q3T136", "database": "AlphaFoldDB", "categories": [] }, { "id": "ENSBTAG00000002037", "url": "https://bgee.org/?page=gene&gene_id=ENSBTAG00000002037", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "ENSBTAG00000049733", "url": "https://bgee.org/?page=gene&gene_id=ENSBTAG00000049733", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "534448", "url": "https://www.ncbi.nlm.nih.gov/gene/534448", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR013243", "url": "https://www.ebi.ac.uk/interpro/entry/IPR013243", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR052237", "url": "https://www.ebi.ac.uk/interpro/entry/IPR052237", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "bta:534448", "url": "https://www.genome.jp/dbget-bin/www_bget?bta:534448", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "HLVVCHV", "url": "https://omabrowser.org/oma/group/HLVVCHV/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "A0A3Q1M8X5", "url": "https://www.orthodb.org/?gene=A0A3Q1M8X5", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "F1N344", "url": "https://www.orthodb.org/?gene=F1N344", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "Q3T136", "url": "https://www.orthodb.org/?gene=Q3T136", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR15117", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR15117", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR15117:SF9", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR15117:SF9", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF08313", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF08313", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "NP_001030484", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001030484", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A3Q1M8X5", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1M8X5", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A3Q1M8X5-1", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1M8X5-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0AAA9S7Q1", "url": "https://www.uniprot.org/uniprotkb/A0AAA9S7Q1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0AAA9S7Q1-1", "url": "https://www.uniprot.org/uniprotkb/A0AAA9S7Q1-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0AAA9TYY3", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TYY3", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0AAA9TYY3-1", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TYY3-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0AAF6ZBY8", "url": "https://www.uniprot.org/uniprotkb/A0AAF6ZBY8", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0AAF6ZBY8-1", "url": "https://www.uniprot.org/uniprotkb/A0AAF6ZBY8-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0ABI0NKH4", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NKH4", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0ABI0NKH4-1", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NKH4-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0ABI0P032", "url": "https://www.uniprot.org/uniprotkb/A0ABI0P032", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0ABI0P032-1", "url": "https://www.uniprot.org/uniprotkb/A0ABI0P032-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0ABI0P132", "url": "https://www.uniprot.org/uniprotkb/A0ABI0P132", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0ABI0P132-1", "url": "https://www.uniprot.org/uniprotkb/A0ABI0P132-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0ABI0P384", "url": "https://www.uniprot.org/uniprotkb/A0ABI0P384", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0ABI0P384-1", "url": "https://www.uniprot.org/uniprotkb/A0ABI0P384-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0ABI0P3V7", "url": "https://www.uniprot.org/uniprotkb/A0ABI0P3V7", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0ABI0P3V7-1", "url": "https://www.uniprot.org/uniprotkb/A0ABI0P3V7-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "F1N344", "url": "https://www.uniprot.org/uniprotkb/F1N344", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "F1N344-1", "url": "https://www.uniprot.org/uniprotkb/F1N344-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "Q3T136", "url": "https://www.uniprot.org/uniprotkb/Q3T136", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "Q3T136-1", "url": "https://www.uniprot.org/uniprotkb/Q3T136-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MTSERSRIPCLSAAAAEGTGKKQQEGRAMATLDRKVPSPEAFLGKPWSSWIDAAKLHCSDNVDLEEAGKEGGKSREVMRLNKEDMHLFGHYPAHDDFYLVVCSACNQVVKPQVFQSHCGRKQDKRNEGIFRNGPEDIQAIEKKQM", "length": 145, "header": "sp|Q3T136-1|AT7L1_BOVIN Isoform 1 of Ataxin-7-like protein 1 OS=Bos taurus OX=9913 GN=ATXN7L1 PE=2 SV=2 CANONICAL=Q3T136-1" }, "isoforms": [ { "isoform_ac": "A0A3Q1M8X5-1", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1M8X5/entry", "sequence": { "sequence": "MTSERSRIPCLSAAAAEGTGKKQQEGRAMATLDRKVPSPEAFLGKPWSSWIDAAKLHCSDNVDLEEAGKEGGKSREVMRLNKEAFCNPLHGGFFSSWTSGLRRLPAFSTRPSEELPDMHLFGHYPAHDDFYLVVCSACNQVVKPQVFQSHCGCCWTSQFPKLQCALSSRTVVPNLLV", "length": 177, "header": "tr|A0A3Q1M8X5-1|AT7L1_BOVIN Computationally mapped isoform of Ataxin-7-like protein 1 OS=Bos taurus OX=9913 GN=ATXN7L1 PE=2 SV=2 CANONICAL=Q3T136-1" }, "locus": { "chromosome": "4", "start_pos": 46954179, "end_pos": 46856957, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000076636.3", "url": "https://www.ensembl.org/id/ENSBTAT00000076636.3" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000066578.2", "url": "https://www.ensembl.org/id/ENSBTAP00000066578.2" } ] } }, { "isoform_ac": "A0AAA9S7Q1-1", "url": "https://www.uniprot.org/uniprotkb/A0AAA9S7Q1/entry", "sequence": { "sequence": "MTSERSRIPCLSAAAAEGTGKKQQEGRAMATLDRKVPSPEAFLGKPWSSWIDAAKLHCSDNVDLEEAGKEGGKSREVMRLNKEDMHLFGHYPAHDDFYLVVCSACNQVVKPQVFQSHCERRHGSMCRPSPSPASPPSNSRTSLVQVKTKTCLSGHNSASSSSKPFKTPKDNLLTSSSKQHTIFSAKGSRDKPCVPVPVVSLEKIPNLVKADGANVKMNSTTTPAVPSCSTSSSAVSTPPVIKPVLMSKSVPPSPEKILNGKGILSTTIDKKHQNGTKNNNKPYRRLSEREFDPNKHCGVLDPETKKPCTRSLTCKTHSLSHRRAVPGRKKQFDLLLAEHKAKSREKEVKDKEHLLTSAREVLPNPPGPAQDSLPGPSGSSGPEPKVASPAKSRPPNSVLPRPSSANSISSSTSSNHSGYTPEPPLPPVGGDLASRLSSDEGEMDGTDESEKLLDCHFSTHHPRPLAFCSFGSRLMGRGYYVFDRRWDRFRVALNSMVEKHLNSQMWKHRNPSHRASGPSPLFRTCLTNLLSLSNIGAAWVSTLESVAPRCPLNLAAQTPGPDGPEPGGMAADGGVEDIRKKRNGQDSFFFNKHLTLHQETPTQYSLSARKIPPAADSPMPSPAAHLTTPVPASVLQPFSNPSAVYLPSAPISSRLTSSYIMTSAMLSNAAFVTSPDPSALMSHTTAFPHVAATLSIMDSTFKAPPAVSPIPAVIASPSHKPSKTKTSKSSKVKDLSARSDESPSNKKRKPQSSTSSSSSSLPLQTSLASPLSGPHKKNCVLNASSALNSYQAAPPYNSLSVHNSNNGVSPLSAKLEPSGRTSLPGGPTDLVRHVGSGGGSSDSCPLSVPTLAGDLSLASHNAVSSLPLSFDKSEGKKRKNSSSSSKACKITKMPGMNSVHRKNPPSLLAPVPDPVNSTSSRQVRGPSFQEPPGTAQGGGLGNRAAPPPPTPA", "length": 952, "header": "tr|A0AAA9S7Q1-1|AT7L1_BOVIN Computationally mapped isoform of Ataxin-7-like protein 1 OS=Bos taurus OX=9913 GN=ATXN7L1 PE=2 SV=2 CANONICAL=Q3T136-1" }, "locus": { "chromosome": "4", "start_pos": 46954179, "end_pos": 46706587, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000092539.2", "url": "https://www.ensembl.org/id/ENSBTAT00000092539.2" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000079961.2", "url": "https://www.ensembl.org/id/ENSBTAP00000079961.2" } ] } }, { "isoform_ac": "A0AAA9TYY3-1", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TYY3/entry", "sequence": { "sequence": "MTSERSRIPCLSAAAAEGTGKKQQEGRAMATLDRKVPSPEAFLGKPWSSWIDAAKLHCSDNVDLEEAGKEGGKSREVMRLNKEAFCNPLHGGFFSSWTSGLRRLPAFSTRPSEELPDGMKASGPMNLKKQDGGRGCASEQPLLKSTVYSDFREKAEFKERFDSYFHFAPAT", "length": 171, "header": "tr|A0AAA9TYY3-1|A0AAA9TYY3_BOVIN Computationally mapped isoform of Ataxin 7 like 1 OS=Bos taurus OX=9913 GN=ATXN7L1 PE=4 SV=1 CANONICAL=Q3T136-1" }, "locus": { "chromosome": "4", "start_pos": 46954179, "end_pos": 46873099, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000111221.2", "url": "https://www.ensembl.org/id/ENSBTAT00000111221.2" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000102448.1", "url": "https://www.ensembl.org/id/ENSBTAP00000102448.1" } ] } }, { "isoform_ac": "A0AAF6ZBY8-1", "url": "https://www.uniprot.org/uniprotkb/A0AAF6ZBY8/entry", "sequence": { "sequence": "MTSERSRIPCLSAAAAEGTGKKQQEGRAMATLDRKVPSPEAFLGKPWSSWIDAAKLHCSDNVDLEEAGKEGGKSREVMRLNKEAFCNPLHGGFFSSWTSGLRRLPAFSTRPSEELPDMHLFGHYPAHDDFYLVVCSACNQVVKPQVFQSHCGALLIPFSKCQQSIYFLKGESKTREMKASSGMDQRTSKP", "length": 190, "header": "tr|A0AAF6ZBY8-1|A0AAF6ZBY8_BOVIN Computationally mapped isoform of Ataxin 7 like 1 OS=Bos taurus OX=9913 GN=ATXN7L1 PE=4 SV=2 CANONICAL=Q3T136-1" }, "locus": { "chromosome": "4", "start_pos": 46954179, "end_pos": 46834605, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000033748.7", "url": "https://www.ensembl.org/id/ENSBTAT00000033748.7" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000033657.6", "url": "https://www.ensembl.org/id/ENSBTAP00000033657.6" } ] } }, { "isoform_ac": "A0ABI0NKH4-1", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NKH4/entry", "sequence": { "sequence": "MTSERSRIPCLSAAAAEGTGKKQQEGRAMATLDRKVPSPEAFLGKPWSSWIDAAKLHCSDNVDLEEAGKEGGKSREVMRLNKEAFCNPLHGGFFSSWTSGLRRLPAFSTRPSEELPELMEPYPQSGAGAGMSRME", "length": 135, "header": "tr|A0ABI0NKH4-1|A0ABI0NKH4_BOVIN Computationally mapped isoform of Ataxin 7 like 1 OS=Bos taurus OX=9913 GN=ATXN7L1 PE=4 SV=1 CANONICAL=Q3T136-1" }, "locus": { "chromosome": "4", "start_pos": 46954179, "end_pos": 46873257, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000153469.1", "url": "https://www.ensembl.org/id/ENSBTAT00000153469.1" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000105209.1", "url": "https://www.ensembl.org/id/ENSBTAP00000105209.1" } ] } }, { "isoform_ac": "A0ABI0P032-1", "url": "https://www.uniprot.org/uniprotkb/A0ABI0P032/entry", "sequence": { "sequence": "MTSERSRIPCLSAAAAEGTGKKQQEGRAMATLDRKVPSPEAFLGKPWSSWIDAAKLHCSDNVDLEEAGKEGGKSREVMRLNKEDMHLFGHYPAHDDFYLVVCSACNQVVKPQVFQSHCERRHGSMCRPSPSPASPPSNSRTSLVQVKTKTCLSGHNSASSSSKPFKTPKDNLLTSSSKQHTIFSAKGSRDKPCVPVPVVSLEKIPNLVKADGANVKMNSTTTPAVPSCSTSSSAVSTPPVIKPVLMSKSVPPSPEKILNGKGILSTTIDKKHQNGTKNNNKPYRRLSEREFDPNKHCGVLDPETKKPCTRSLTCKTHSLSHRRAVPGRKKQFDLLLAEHKAKSREKEVKDKEHLLTSAREVLPNPPGPAQDSLPGPSGSSGPEPKVASPAKSRPPNSVLPRPSSANSISSSTSSNHSGYTPEPPLPPVGGDLASRLSSDEGEMDGTDESEKLLDCHFSTHHPRPLAFCSFGSRLMGRGYYVFDRRWDRFRVALNSMVEKHLNSQMWKKIPPAADSPMPSPAAHLTTPVPASVLQPFSNPSAVYLPSAPISSRLTSSYIMTSAMLSNAAFVTSPDPSALMSHTTAFPHVAATLSIMDSTFKAPPAVSPIPAVIASPSHKPSKTKTSKSSKVKDLSARSDESPSNKKRKPQSSTSSSSSSLPLQTSLASPLSGPHKKNCVLNASSALNSYQAAPPYNSLSVHNSNNGVSPLSAKLEPSGRTSLPGGPTDLVRHVGSGGGSSDSCPLSVPTLAGDLSLASHNAVSSLPLSFDKSEGKKRKNSSSSSKACKITKMPGMNSVHRKNPPSLLAPVPDPVNSTSSRQVGKNSSLALSQSSPSSISSPGHSRPNTNRTGRIRTLP", "length": 857, "header": "tr|A0ABI0P032-1|A0ABI0P032_BOVIN Computationally mapped isoform of Ataxin 7 like 1 OS=Bos taurus OX=9913 GN=ATXN7L1 PE=4 SV=1 CANONICAL=Q3T136-1" }, "locus": { "chromosome": "4", "start_pos": 46954179, "end_pos": 46701876, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000150976.1", "url": "https://www.ensembl.org/id/ENSBTAT00000150976.1" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000106223.1", "url": "https://www.ensembl.org/id/ENSBTAP00000106223.1" } ] } }, { "isoform_ac": "A0ABI0P132-1", "url": "https://www.uniprot.org/uniprotkb/A0ABI0P132/entry", "sequence": { "sequence": "MTSERSRIPCLSAAAAEGTGKKQQEGRAMATLDRKVPSPEAFLGKPWSSWIDAAKLHCSDNVDLEEAGKEGGKSREVMRLNKEERRHGSMCRPSPSPASPPSNSRTSLVQVKTKTCLSGHNSASSSSKPFKTPKDNLLTSSSKQHTIFSAKGSRDKPCVPVPVVSLEKIPNLVKADGANVKMNSTTTPAVPSCSTSSSAVSTPPVIKPVLMSKSVPPSPEKILNGKGILSTTIDKKHQNGTKNNNKPYRRLSEREFDPNKHCGVLDPETKKPCTRSLTCKTHSLSHRRAVPGRKKQFDLLLAEHKAKSREKEVKDKEHLLTSAREVLPNPPGPAQDSLPGPSGSSGPEPKVASPAKSRPPNSVLPRPSSANSISSSTSSNHSGYTPEPPLPPVGGDLASRLSSDEGEMDGTDESEKLLDCHFSTHHPRPLAFCSFGSRLMGRGYYVFDRRWDRFRVALNSMVEKHLNSQMWKHRNPSHRASGPSPLFRTCLTNLLSLSNIGAAWVSTLESVAPRCPLNLAAQTPGPDGPEPGGMAADGGVEDIRKKRNGQDSFFFNKHLTLHQETPTQYSLSARKIPPAADSPMPSPAAHLTTPVPASVLQPFSNPSAVYLPSAPISSRLTSSYIMTSAMLSNAAFVTSPDPSALMSHTTAFPHVAATLSIMDSTFKAPPAVSPIPAVIASPSHKPSKTKTSKSSKVKDLSARSDESPSNKKRKPQSSTSSSSSSLPLQTSLASPLSGPHKKNCVLNASSALNSYQAAPPYNSLSVHNSNNGVSPLSAKLEPSGRTSLPGGPTDLVRHVGSGGGSSDSCPLSVPTLAGDLSLASHNAVSSLPLSFDKSEGKKRKNSSSSSKACKITKMPGMNSVHRKNPPSLLAPVPDPVNSTSSRQVGKNSSLALSQSSPSSISSPGHSRPKNTNRTGRIRTLP", "length": 925, "header": "tr|A0ABI0P132-1|A0ABI0P132_BOVIN Computationally mapped isoform of Ataxin 7 like 1 OS=Bos taurus OX=9913 GN=ATXN7L1 PE=4 SV=1 CANONICAL=Q3T136-1" }, "locus": { "chromosome": "4", "start_pos": 46954179, "end_pos": 46701876, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000143995.1", "url": "https://www.ensembl.org/id/ENSBTAT00000143995.1" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000104154.1", "url": "https://www.ensembl.org/id/ENSBTAP00000104154.1" } ] } }, { "isoform_ac": "A0ABI0P384-1", "url": "https://www.uniprot.org/uniprotkb/A0ABI0P384/entry", "sequence": { "sequence": "MTSERSRIPCLSAAAAEGTGKKQQEGRAMATLDRKVPSPEAFLGKPWSSWIDAAKLHCSDNVDLEEAGKEGGKSREVMRLNKEAFCNPLHGGFFSSWTSGLRRLPAFSTRPSEELPDMHLFGHYPAHDDFYLVVCSACNQVVKPQVFQSHCERRHGSMCRPSPSPASPPSNSRTSLVQVKTKTCLSGHNSASSSSKPFKTPKDNLLTSSSKQHTIFSAKGSRDKPCVPVPVVSLEKIPNLVKADGANVKMNSTTTPAVPSCSTSSSAVSTPPVIKPVLMSKSVPPSPEKILNGKGILSTTIDKKHQNGTKNNNKPYRRLSEREFDPNKHCGVLDPETKKPCTRSLTCKTHSLSHRRAVPGRKKQFDLLLAEHKAKSREKEVKDKEHLLTSAREVLPNPPGPAQDSLPGPSGSSGPEPKVASPAKSRPPNSVLPRPSSANSISSSTSSNHSGYTPEPPLPPVGGDLASRLSSDEGEMDGTDESEKLLDCHFSTHHPRPLAFCSFGSRLMGRGYYVFDRRWDRFRVALNSMVEKHLNSQMWKKIPPAADSPMPSPAAHLTTPVPASVLQPFSNPSAVYLPSAPISSRLTSSYIMTSAMLSNAAFVTSPDPSALMSHTTAFPHVAATLSIMDSTFKAPPAVSPIPAVIASPSHKPSKTKTSKSSKVKDLSARSDESPSNKKRKPQSSTSSSSSSLPLQTSLASPLSGPHKKNCVLNASSALNSYQAAPPYNSLSVHNSNNGVSPLSAKLEPSGRTSLPGGPTDLVRHVGSGGGSSDSCPLSVPTLAGDLSLASHNAVSSLPLSFDKSEGKKRKNSSSSSKACKITKMPGMNSVHRKNPPSLLAPVPDPVNSTSSRQVRGPSFQEPPGTAQGGGLGNRAAPPPPTPA", "length": 883, "header": "tr|A0ABI0P384-1|A0ABI0P384_BOVIN Computationally mapped isoform of Ataxin 7 like 1 OS=Bos taurus OX=9913 GN=ATXN7L1 PE=4 SV=1 CANONICAL=Q3T136-1" }, "locus": { "chromosome": "4", "start_pos": 46954179, "end_pos": 46706587, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000145599.1", "url": "https://www.ensembl.org/id/ENSBTAT00000145599.1" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000105709.1", "url": "https://www.ensembl.org/id/ENSBTAP00000105709.1" } ] } }, { "isoform_ac": "A0ABI0P3V7-1", "url": "https://www.uniprot.org/uniprotkb/A0ABI0P3V7/entry", "sequence": { "sequence": "MTSERSRIPCLSAAAAEGTGKKQQEGRAMATLDRKVPSPEAFLGKPWSSWIDAAKLHCSDNVDLEEAGKEGGKSREVMRLNKEAFCNPLHGGFFSSWTSGLRRLPAFSTRPSEELPELMEPYPQSGAGAGMSRICTCLATTQHTTTSTSWCAAPVTRSSSRRSSSPTAGESKTREMKASSGMDQRTSKP", "length": 189, "header": "tr|A0ABI0P3V7-1|A0ABI0P3V7_BOVIN Computationally mapped isoform of Ataxin 7 like 1 OS=Bos taurus OX=9913 GN=ATXN7L1 PE=4 SV=1 CANONICAL=Q3T136-1" }, "locus": { "chromosome": "4", "start_pos": 46954179, "end_pos": 46834605, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000142669.1", "url": "https://www.ensembl.org/id/ENSBTAT00000142669.1" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000105467.1", "url": "https://www.ensembl.org/id/ENSBTAP00000105467.1" } ] } }, { "isoform_ac": "F1N344-1", "url": "https://www.uniprot.org/uniprotkb/F1N344/entry", "sequence": { "sequence": "MTSERSRIPCLSAAAAEGTGKKQQEGRAMATLDRKVPSPEAFLGKPWSSWIDAAKLHCSDNVDLEEAGKEGGKSREVMRLNKEDMHLFGHYPAHDDFYLVVCSACNQVVKPQVFQSHCERRHGSMCRPSPSPASPPSNSRTSLVQVKTKTCLSGHNSASSSSKPFKTPKDNLLTSSSKQHTIFSAKGSRDKPCVPVPVVSLEKIPNLVKADGANVKMNSTTTPAVPSCSTSSSAVSTPPVIKPVLMSKSVPPSPEKILNGKGILSTTIDKKHQNGTKNNNKPYRRLSEREFDPNKHCGVLDPETKKPCTRSLTCKTHSLSHRRAVPGRKKQFDLLLAEHKAKSREKEVKDKEHLLTSAREVLPNPPGPAQDSLPGPSGSSGPEPKVASPAKSRPPNSVLPRPSSANSISSSTSSNHSGYTPEPPLPPVGGDLASRLSSDEGEMDGTDESEKLLDCHFSTHHPRPLAFCSFGSRLMGRGYYVFDRRWDRFRVALNSMVEKHLNSQMWKKIPPAADSPMPSPAAHLTTPVPASVLQPFSNPSAVYLPSAPISSRLTSSYIMTSAMLSNAAFVTSPDPSALMSHTTAFPHVAATLSIMDSTFKAPPAVSPIPAVIASPSHKPSKTKTSKSSKVKDLSARSDESPSNKKRKPQSSTSSSSSSLPLQTSLASPLSGPHKKNCVLNASSALNSYQAAPPYNSLSVHNSNNGVSPLSAKLEPSGRTSLPGGPTDLVRHVGSGGGSSDSCPLSVPTLAGDLSLASHNAVSSLPLSFDKSEGKKRKNSSSSSKACKITKMPGMNSVHRKNPPSLLAPVPDPVNSTSSRQDCCLGNPPAQLRCHLCVEEGAQMSKPSTGRLNNVPKVTQ", "length": 859, "header": "tr|F1N344-1|AT7L1_BOVIN Computationally mapped isoform of Ataxin-7-like protein 1 OS=Bos taurus OX=9913 GN=ATXN7L1 PE=2 SV=5 CANONICAL=Q3T136-1" }, "locus": { "chromosome": "4", "start_pos": 46954179, "end_pos": 46705063, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000002637.8", "url": "https://www.ensembl.org/id/ENSBTAT00000002637.8" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000002637.8", "url": "https://www.ensembl.org/id/ENSBTAP00000002637.8" } ] } }, { "isoform_ac": "Q3T136-1", "url": "https://www.uniprot.org/uniprotkb/Q3T136/entry#Q3T136-1", "sequence": { "sequence": "MTSERSRIPCLSAAAAEGTGKKQQEGRAMATLDRKVPSPEAFLGKPWSSWIDAAKLHCSDNVDLEEAGKEGGKSREVMRLNKEDMHLFGHYPAHDDFYLVVCSACNQVVKPQVFQSHCGRKQDKRNEGIFRNGPEDIQAIEKKQM", "length": 145, "header": "sp|Q3T136-1|AT7L1_BOVIN Isoform 1 of Ataxin-7-like protein 1 OS=Bos taurus OX=9913 GN=ATXN7L1 PE=2 SV=2 CANONICAL=Q3T136-1" }, "locus": {} } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [ { "id": "bta:534448", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?bta:534448", "resource": "KEGG Pathway" } ], "orthologs": [], "go_annotation": {}, "pro_annotation": [], "site_annotation": [], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [ { "pdb_id": "AF-Q3T136-F1", "pdb_chain": "global", "start_pos": 1, "end_pos": 145, "overlap": "1.0", "method": "AlphaFold", "type": "alphafold", "resolution": -1.0, "url": "https://data.glygen.org/ln2downloads/pdb/current/AF-Q3T136-F1.pdb", "url_external": "https://alphafold.ebi.ac.uk/entry/Q3T136" } ], "lectin_list": [], "domain_list": [], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ], "tool_support": { "graph_view": "yes" } }, { "uniprot_canonical_ac": "J9JH87-1", "uniprot_ac": "J9JH87", "uniprot_id": "J9JH87_BOVIN", "mass": { "chemical_mass": 35312.0, "monoisotopic_mass": 35312.0 }, "refseq": { "ac": "NP_001030348", "name": "Krueppel-like factor 6", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001030348" }, "gene_names": [ { "name": "KLF6", "type": "recommended", "evidence": [ { "id": "J9JH87", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/J9JH87" } ] }, { "name": "KLF6", "type": "synonym", "evidence": [ { "id": "NP_001030348", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001030348" } ] } ], "protein_names": [ { "name": "KLF transcription factor 6", "type": "synonym", "evidence": [ { "id": "J9JH87", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/J9JH87/entry#names_and_taxonomy" } ] }, { "name": "Krueppel-like factor 6", "type": "synonym", "evidence": [ { "id": "NP_001030348", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001030348" } ] }, { "name": "Kruppel like factor 6", "type": "synonym", "evidence": [ { "id": "NP_001030348", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001030348" } ] } ], "function": [ { "annotation": "The KLF6 gene can be used as a candidate gene for growth and carcass traits for marker-assisted selection.", "evidence": [ { "database": "RefSeq", "id": "NP_001030348", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001030348" }, { "database": "PubMed", "id": "30880114", "url": "https://glygen.org/publication/PubMed/30880114" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Bos taurus", "taxid": 9913, "evidence": [ { "database": "UniProtKB", "id": "J9JH87", "url": "https://www.uniprot.org/uniprotkb/J9JH87" } ], "common_name": "Bovine", "glygen_name": "Bovine", "reference_species": "Bos taurus [9913]" } ], "gene": [ { "name": "KLF6", "url": "https://www.uniprot.org/uniprotkb/J9JH87", "locus": { "chromosome": "13", "start_pos": 44604377, "end_pos": 44596333, "strand": "-", "evidence": [ { "database": "Ensembl Gene", "id": "ENSBTAG00000015188", "url": "https://www.ensembl.org/id/ENSBTAG00000015188" } ] } } ], "crossref": [ { "id": "J9JH87", "url": "https://alphafold.ebi.ac.uk/entry/J9JH87", "database": "AlphaFoldDB", "categories": [] }, { "id": "ENSBTAG00000015188", "url": "https://bgee.org/?page=gene&gene_id=ENSBTAG00000015188", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "cd21586", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd21586", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "505884", "url": "https://www.ncbi.nlm.nih.gov/gene/505884", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR013087", "url": "https://www.ebi.ac.uk/interpro/entry/IPR013087", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR036236", "url": "https://www.ebi.ac.uk/interpro/entry/IPR036236", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "bta:505884", "url": "https://www.genome.jp/dbget-bin/www_bget?bta:505884", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "HLWNAIT", "url": "https://omabrowser.org/oma/group/HLWNAIT/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "A0A3Q1M9X5", "url": "https://www.orthodb.org/?gene=A0A3Q1M9X5", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "J9JH87", "url": "https://www.orthodb.org/?gene=J9JH87", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR23235", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR23235", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR23235:SF50", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR23235:SF50", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00096", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00096", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "NP_001030348", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001030348", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A3Q1M9X5", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1M9X5", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A3Q1M9X5-1", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1M9X5-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0AAA9SLC4", "url": "https://www.uniprot.org/uniprotkb/A0AAA9SLC4", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0AAA9SLC4-1", "url": "https://www.uniprot.org/uniprotkb/A0AAA9SLC4-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0AAA9SVU2", "url": "https://www.uniprot.org/uniprotkb/A0AAA9SVU2", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0AAA9SVU2-1", "url": "https://www.uniprot.org/uniprotkb/A0AAA9SVU2-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0AAA9SXU9", "url": "https://www.uniprot.org/uniprotkb/A0AAA9SXU9", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0AAA9SXU9-1", "url": "https://www.uniprot.org/uniprotkb/A0AAA9SXU9-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "J9JH87", "url": "https://www.uniprot.org/uniprotkb/J9JH87", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "J9JH87-1", "url": "https://www.uniprot.org/uniprotkb/J9JH87-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MNFPGAAGTAAALPTADRKPPCFYSSGDGLFQPDMDVLPMCSIFQELQIVHETGYFSALPSLEEYWQQTCLELERYLQSEPCYVSASEIKFDSQEDLWTKIILAREKKEDADLKVSSSGPPEDALHSPGFSYNLETNSLNSDVSSESSDSSEELSPTTKFTSDPISEVLVNSGNLSSSVTSTPPSSPELSREPSHLWGCVPGELHPPGKARGGTSGKPGDKGSGDASPDGRRRVHRCHFNGCRKVYTKSSHLKAHQRTHTGEKPYRCSWEGCEWRFARSDELTRHFRKHTGAKPFKCSHCDRCFSRSDHLALHMKRHL", "length": 318, "header": "tr|J9JH87-1|J9JH87_BOVIN Isoform 1 of KLF transcription factor 6 OS=Bos taurus OX=9913 GN=KLF6 PE=4 SV=3 CANONICAL=J9JH87-1" }, "isoforms": [ { "isoform_ac": "A0A3Q1M9X5-1", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1M9X5/entry", "sequence": { "sequence": "MNFPGAAGTAAALPTADRKPPCFYSSGDGLFQPDMDVLPMCSIFQELQIVHETGYFSALPSLEEYWQQTCLELERYLQSEPCYVSASEIKFDSQEDLWTKIILAREKKEDADLKVSSSGPPEDALHSPGFSYNLETNSLNSDVSSESSDSSEELSPTTKFTSDPISEVLVNSGNLSSSVTSTPPSSPELSREPSHLWGCVPGELHPPGKARGGTSGKPGDKGSGDASPDGRRRVHRCHFNGCRKVYTKSSHLKAHQRTHTGVSPGPTTWPCT", "length": 272, "header": "tr|A0A3Q1M9X5-1|J9JH87_BOVIN Computationally mapped isoform of KLF transcription factor 6 OS=Bos taurus OX=9913 GN=KLF6 PE=4 SV=2 CANONICAL=J9JH87-1" }, "locus": { "chromosome": "13", "start_pos": 44603034, "end_pos": 44597409, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000081800.2", "url": "https://www.ensembl.org/id/ENSBTAT00000081800.2" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000067378.2", "url": "https://www.ensembl.org/id/ENSBTAP00000067378.2" } ] } }, { "isoform_ac": "A0AAA9SLC4-1", "url": "https://www.uniprot.org/uniprotkb/A0AAA9SLC4/entry", "sequence": { "sequence": "MECQVARKFEMVGRGDAGVSAVVASGKTCLELERYLQSEPCYVSASEIKFDSQEDLWTKIILAREKKEDADLKVSSSGPPEDALHSPGFSYNLETNSLNSDVSSESSDSSEELSPTTKFTSDPISEVLVNSGNLSSSVTSTPPSSPELSREPSHLWGCVPGELHPPGKARGGTSGKPGDKGSGDASPDGRRRVHRCHFNGCRKVYTKSSHLKAHQRTHTGEKPYRCSWEGCEWRFARSDELTRHFRKHTGAKPFKCSHCDRCFSRSDHLALHMKRHL", "length": 277, "header": "tr|A0AAA9SLC4-1|J9JH87_BOVIN Computationally mapped isoform of KLF transcription factor 6 OS=Bos taurus OX=9913 GN=KLF6 PE=4 SV=1 CANONICAL=J9JH87-1" }, "locus": { "chromosome": "13", "start_pos": 44603048, "end_pos": 44598046, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000127420.2", "url": "https://www.ensembl.org/id/ENSBTAT00000127420.2" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000086058.1", "url": "https://www.ensembl.org/id/ENSBTAP00000086058.1" } ] } }, { "isoform_ac": "A0AAA9SVU2-1", "url": "https://www.uniprot.org/uniprotkb/A0AAA9SVU2/entry", "sequence": { "sequence": "MVGRGDAGVSAVVASGKTCLELERYLQSEPCYVSASEIKFDSQEDLWTKIILAREKKEDADLKVSSSGPPEDALHSPGFSYNLETNSLNSDVSSESSDSSEELSPTTKFTSDPISEVLVNSGNLSSSVTSTPPSSPELSREPSHLWGCVPGELHPPGKARGGTSGKPGDKGSGDASPDGRRRVHRCHFNGCRKVYTKSSHLKAHQRTHTGEKPYRCSWEGCEWRFARSDELTRHFRKHTGAKPFKCSHCDRCFSRSDHLALHMKRHL", "length": 267, "header": "tr|A0AAA9SVU2-1|J9JH87_BOVIN Computationally mapped isoform of KLF transcription factor 6 OS=Bos taurus OX=9913 GN=KLF6 PE=4 SV=1 CANONICAL=J9JH87-1" }, "locus": { "chromosome": "13", "start_pos": 44603048, "end_pos": 44599397, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000110407.2", "url": "https://www.ensembl.org/id/ENSBTAT00000110407.2" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000088138.1", "url": "https://www.ensembl.org/id/ENSBTAP00000088138.1" } ] } }, { "isoform_ac": "A0AAA9SXU9-1", "url": "https://www.uniprot.org/uniprotkb/A0AAA9SXU9/entry", "sequence": { "sequence": "PRRLILGTCLELERYLQSEPCYVSASEIKFDSQEDLWTKIILAREKKEDADLKVSSSGPPEDALHSPGFSYNLETNSLNSDVSSESSDSSEELSPTTKFTSDPISEVLVNSGNLSSSVTSTPPSSPELSREPSHLWGCVPGELHPPGKARGGTSGKPGDKGSGDASPDGRRRVHRCHFNGCRKVYTKSSHLKAHQRTHTGEKPYRCSWEGCEWRFARSDELTRHFRKHTGAKPFKCSHCDRCFSRSDHLALHMKRHL", "length": 257, "header": "tr|A0AAA9SXU9-1|J9JH87_BOVIN Computationally mapped isoform of KLF transcription factor 6 OS=Bos taurus OX=9913 GN=KLF6 PE=4 SV=1 CANONICAL=J9JH87-1" }, "locus": { "chromosome": "13", "start_pos": 44603048, "end_pos": 44599035, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000092486.2", "url": "https://www.ensembl.org/id/ENSBTAT00000092486.2" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000089060.1", "url": "https://www.ensembl.org/id/ENSBTAP00000089060.1" } ] } }, { "isoform_ac": "J9JH87-1", "url": "https://www.uniprot.org/uniprotkb/J9JH87/entry", "sequence": { "sequence": "MNFPGAAGTAAALPTADRKPPCFYSSGDGLFQPDMDVLPMCSIFQELQIVHETGYFSALPSLEEYWQQTCLELERYLQSEPCYVSASEIKFDSQEDLWTKIILAREKKEDADLKVSSSGPPEDALHSPGFSYNLETNSLNSDVSSESSDSSEELSPTTKFTSDPISEVLVNSGNLSSSVTSTPPSSPELSREPSHLWGCVPGELHPPGKARGGTSGKPGDKGSGDASPDGRRRVHRCHFNGCRKVYTKSSHLKAHQRTHTGEKPYRCSWEGCEWRFARSDELTRHFRKHTGAKPFKCSHCDRCFSRSDHLALHMKRHL", "length": 318, "header": "tr|J9JH87-1|J9JH87_BOVIN Isoform 1 of KLF transcription factor 6 OS=Bos taurus OX=9913 GN=KLF6 PE=4 SV=3 CANONICAL=J9JH87-1" }, "locus": { "chromosome": "13", "start_pos": 44603048, "end_pos": 44597409, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000020207.7", "url": "https://www.ensembl.org/id/ENSBTAT00000020207.7" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000020207.7", "url": "https://www.ensembl.org/id/ENSBTAP00000020207.7" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [ { "title": "Expression of the bovine KLF6 gene polymorphisms and their association with carcass and body measures in Qinchuan cattle (Bos Taurus).", "journal": "Genomics", "date": "2020-01", "authors": "Raza Sayed Haidar Abbas, Khan Rajwali, Schreurs Nicola M, Guo Hongfang, Gui Lin-Sheng, Mei Chugang, Zan Linsen", "evidence": [ { "database": "RefSeq", "id": "NP_001030348", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001030348" } ], "reference": [ { "type": "PubMed", "id": "30880114", "url": "https://glygen.org/publication/PubMed/30880114" } ] } ], "pathway": [ { "id": "bta:505884", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?bta:505884", "resource": "KEGG Pathway" } ], "orthologs": [], "go_annotation": { "categories": [ { "name": "Molecular Function", "total": 3, "go_terms": [ { "name": "zinc ion binding", "id": "GO:0008270", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008270", "evidence": [ { "database": "UniProtKB", "id": "J9JH87", "url": "https://www.uniprot.org/uniprotkb/J9JH87" } ], "pmid": "" }, { "name": "RNA polymerase II cis-regulatory region sequence-specific DNA binding", "id": "GO:0000978", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000978", "evidence": [ { "database": "UniProtKB", "id": "J9JH87", "url": "https://www.uniprot.org/uniprotkb/J9JH87" } ], "pmid": "" }, { "name": "DNA-binding transcription activator activity, RNA polymerase II-specific", "id": "GO:0001228", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0001228", "evidence": [ { "database": "UniProtKB", "id": "J9JH87", "url": "https://www.uniprot.org/uniprotkb/J9JH87" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 3, "go_terms": [ { "name": "nucleus", "id": "GO:0005634", 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"end_pos": 176 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": 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"https://www.rcsb.org/structure/9FQR", "database": "PDB", "categories": [ "3D Structure" ] }, { "id": "PF17670", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF17670", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "NP_001070522", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001070522", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A3Q1MA93", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1MA93", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A3Q1MA93-1", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1MA93-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "Q32L72", "url": "https://www.uniprot.org/uniprotkb/Q32L72", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "Q32L72-1", "url": "https://www.uniprot.org/uniprotkb/Q32L72-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MTAIRLREFIDRRPAIPPSIFIVHQGKDLRGYYTGQLARVHYDYSVKRSPRPLIDLDIPFKKKSQYQPQLDQQTLIQYICFRRRSKPAEPWYKETSYQRDYSLPFYKTDWDRKLATVSSNPRPLNSLPEHYCCEGRWL", "length": 138, "header": "sp|Q32L72-1|SMIP3_BOVIN Isoform 1 of Protein SPMIP3 OS=Bos taurus OX=9913 GN=SPMIP3 PE=1 SV=1 CANONICAL=Q32L72-1" }, "isoforms": [ { "isoform_ac": "A0A3Q1MA93-1", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1MA93/entry", "sequence": { "sequence": "WPYIFSYFFLDILKLIPDNIFIVHQGKDLRGYYTGQLARVHYDYSVKRSPRPLIDLDIPFKKKSQYQPQLDQQTLIQYICFRRRSKPAEPWYKETSYQRDYSLPFYKTDWDRKLATVSSNPRPLNSLPEHYCCEGRWL", "length": 138, "header": "tr|A0A3Q1MA93-1|SMIP3_BOVIN Computationally mapped isoform of Protein SPMIP3 OS=Bos taurus OX=9913 GN=SPMIP3 PE=1 SV=2 CANONICAL=Q32L72-1" }, "locus": { "chromosome": "16", "start_pos": 32820250, "end_pos": 32802351, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000079409.2", "url": "https://www.ensembl.org/id/ENSBTAT00000079409.2" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000067133.2", "url": "https://www.ensembl.org/id/ENSBTAP00000067133.2" } ] } }, { "isoform_ac": "Q32L72-1", "url": "https://www.uniprot.org/uniprotkb/Q32L72/entry#Q32L72-1", "sequence": { "sequence": "MTAIRLREFIDRRPAIPPSIFIVHQGKDLRGYYTGQLARVHYDYSVKRSPRPLIDLDIPFKKKSQYQPQLDQQTLIQYICFRRRSKPAEPWYKETSYQRDYSLPFYKTDWDRKLATVSSNPRPLNSLPEHYCCEGRWL", "length": 138, "header": "sp|Q32L72-1|SMIP3_BOVIN Isoform 1 of Protein SPMIP3 OS=Bos taurus OX=9913 GN=SPMIP3 PE=1 SV=1 CANONICAL=Q32L72-1" }, "locus": { "chromosome": "16", "start_pos": 32829207, "end_pos": 32802351, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000047059.2", "url": "https://www.ensembl.org/id/ENSBTAT00000047059.2" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000044294.1", "url": "https://www.ensembl.org/id/ENSBTAP00000044294.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [ { "id": "bta:767994", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?bta:767994", "resource": "KEGG Pathway" } ], "orthologs": [ { "uniprot_canonical_ac": "A0A8I6ACQ9-1", "protein_name": "Sperm microtubule inner protein 3", "gene_name": "Spmip3", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "LKHLLPSEENFFEEGGGPCSLLPKPAIRLYITHQGRDVKGWTTGQLARLHFDYSVKKAPRPLIDLAIPPRSKTPYEPQLDQQTLFRYICYRRLSRPTDKWHNETTYERSYSLPFYELGWDKKLGTISSHPRPVNSVPEVYCCDERNGFARSTF", "length": 153 }, "evidence": [ { "id": "Q32L72", "url": "https://omabrowser.org/oma/group/Q32L72/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "A0A8W4FGA4-1", "protein_name": "Sperm microtubule inner protein 3", "gene_name": "SPMIP3", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MTAIRLREFIDRRPGIPSSIFIAHQGKDLHGYYPGQLARLHYAYSVKRSPRPLIDLEILPKSKNQYQPQLDQQTLIQYICSRRHAKPAEPWHKETTYQRDYSLPFYKTDWDQKLATISSDPRPLNSLPEHYCCEEKWL", "length": 138 }, "evidence": [ { "id": "Q32L72", "url": "https://omabrowser.org/oma/group/Q32L72/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "Q5SVJ3-1", "protein_name": "Protein SPMIP3", "gene_name": "SPMIP3", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MTAIRLREFIERRPVIPPSIFIAHQGRDVQGYYPGQLARLHFDHSAKRAPRPLIDLTIPPKTKYHYQPQLDQQTLIRYICLRRHSKPAEPWYKETTYRRDYSLPFYEIDWNQKLATVSLNPRPLNSLPELYCCEERSSFERNAFKLK", "length": 147 }, "evidence": [ { "id": "Q32L72", "url": "https://omabrowser.org/oma/group/Q32L72/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "Q9DAA7-1", "protein_name": "Protein SPMIP3", "gene_name": "SPMIP3", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MSTIRLREFVERRPSIPPRLYITHQGRDIKGYYPGQLARLHFDYSGRKAPRPLIDLTIPLKSTTPYQPQLDQQTLIRSICSRRLSRPTDLWHNETSYQRDYSLPFYESGWDRKLGTISLHPRPVNSVPEVYCCGGERSSYARSTF", "length": 145 }, "evidence": [ { "id": "Q32L72", "url": "https://omabrowser.org/oma/group/Q32L72/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" } ], "go_annotation": {}, "pro_annotation": [], "site_annotation": [], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [ { "pdb_id": "AF-Q32L72-F1", "pdb_chain": "global", "start_pos": 1, "end_pos": 138, "overlap": "1.0", "method": "AlphaFold", "type": "alphafold", "resolution": -1.0, "url": "https://data.glygen.org/ln2downloads/pdb/current/AF-Q32L72-F1.pdb", "url_external": "https://alphafold.ebi.ac.uk/entry/Q32L72" } ], "lectin_list": [], "domain_list": [], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" }, { "name": "homologset.oma", "label": "OMA Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ], "tool_support": { "graph_view": "yes" } }, { "uniprot_canonical_ac": "Q1LZE8-1", "uniprot_ac": "Q1LZE8", "uniprot_id": "CG025_BOVIN", "mass": { "chemical_mass": 46428.0, "monoisotopic_mass": 46428.0 }, "refseq": { "ac": "NP_001069608", "name": "UPF0415 protein C7orf25 homolog", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001069608" }, "gene_names": [ { "name": "C4H7orf25", "type": "recommended", "evidence": [ { "id": "Q1LZE8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q1LZE8" } ] }, { "name": "C4H7orf25", "type": "synonym", "evidence": [ { "id": "NP_001069608", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001069608" } ] }, { "name": "C7orf25", "type": "synonym", "evidence": [ { "id": "NP_001069608", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001069608" } ] } ], "protein_names": [ { "name": "UPF0415 protein C7orf25 homolog", "type": "recommended", "evidence": [ { "id": "Q1LZE8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q1LZE8/entry#names_and_taxonomy" } ] }, { "name": "UPF0415 protein C7orf25 homolog", "type": "synonym", "evidence": [ { "id": "NP_001069608", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001069608" } ] } ], "function": [], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Bos taurus", "taxid": 9913, "evidence": [ { "database": "UniProtKB", "id": "Q1LZE8", "url": "https://www.uniprot.org/uniprotkb/Q1LZE8" } ], "common_name": "Bovine", "glygen_name": "Bovine", "reference_species": "Bos taurus [9913]" } ], "gene": [ { "name": "", "url": "https://www.uniprot.org/uniprotkb/Q1LZE8", "locus": {} } ], "crossref": [ { "id": "Q1LZE8", "url": "https://alphafold.ebi.ac.uk/entry/Q1LZE8", "database": "AlphaFoldDB", "categories": [] }, { "id": "ENSBTAG00000009472", "url": "https://bgee.org/?page=gene&gene_id=ENSBTAG00000009472", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "538970", "url": "https://www.ncbi.nlm.nih.gov/gene/538970", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR010733", "url": "https://www.ebi.ac.uk/interpro/entry/IPR010733", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR041076", "url": "https://www.ebi.ac.uk/interpro/entry/IPR041076", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "bta:538970", "url": "https://www.genome.jp/dbget-bin/www_bget?bta:538970", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "A0A3Q1MFF6", "url": "https://www.orthodb.org/?gene=A0A3Q1MFF6", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "Q1LZE8", "url": "https://www.orthodb.org/?gene=Q1LZE8", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR13379", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR13379", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR13379:SF0", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR13379:SF0", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF07000", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF07000", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF18474", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF18474", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "NP_001069608", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001069608", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A3Q1MFF6", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1MFF6", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A3Q1MFF6-1", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1MFF6-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0AAF6YTM4", "url": "https://www.uniprot.org/uniprotkb/A0AAF6YTM4", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0AAF6YTM4-1", "url": "https://www.uniprot.org/uniprotkb/A0AAF6YTM4-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "Q1LZE8", "url": "https://www.uniprot.org/uniprotkb/Q1LZE8", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "Q1LZE8-1", "url": "https://www.uniprot.org/uniprotkb/Q1LZE8-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MSAHSMLCERIAIAKELIKRAESLSRSRKGGIEGGAKLCSKLKAELKFLQKVEAGKVAIKESHLQSTNLTHLRAIVESAENLEEVVSVLHVFGYTDTFGEKQTLVVDVVANGGHTWVKAIGRKAEALHNIWLGRGQYGDKSIIEQAEDFLQASHQQPVQYSNPHIIFAFYNSVSSPMAEKLKEMGISVRGDIVAVNSLLDHPEELQPSESESDDEGPELLQVTRVDRENILASVAFPTEIKVDVCKRVNLDITTLITYVSALSYGGCHFIFKEKVLTEQAEQERKEQVLPQLEAFMKDKELFACESAVKDFQSILDTLGGPGERERAAMLIKRINVVPDQPSERALKLVASSKINSRSLTIFGTGDNLKAITMTANSGFVRAANNQGVKFSVFIHQPRALTESKEALATPLPKDCTTDSEH", "length": 421, "header": "sp|Q1LZE8-1|CG025_BOVIN Isoform 1 of UPF0415 protein C7orf25 homolog OS=Bos taurus OX=9913 GN= PE=2 SV=1 CANONICAL=Q1LZE8-1" }, "isoforms": [ { "isoform_ac": "A0A3Q1MFF6-1", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1MFF6/entry", "sequence": { "sequence": "MERNNAVSMSAHSMLCERIAIAKELIKRAESLSRSRKGGIEGGAKLCSKLKAELKFLQKVEAGKVAIKESHLQSTNLTHLRAIVESAENLEEVVSVLHVFGYTDTFGEKQTLVVDVVANGGHTWVKAIGRKAEALHNIWLGRGQYGDKSIIEQAEDFLQASHQQPVQYSNPHIIFAFYNSVSSPMAEKLKEMGISVRGDIVAVNSLLDHPEELQPSESESDDEGPELLQVTRVDRENILASVAFPTEIKVDVCKRVNLDITTLITYVSALSYGGCHFIFKEKVLTEQAEQERKEQVLPQLEAFMKDKELFACESAVKDFQSILDTLGGPGERERAAMLIKRINVVPDQPSERALKLVASSKINSRSLTIFGTGDNLKAITMTANSGFVRAANNQGVKFSVFIHQPRALTESKEALATPLPKDCTTDSEH", "length": 429, "header": "tr|A0A3Q1MFF6-1|CG025_BOVIN Computationally mapped isoform of UPF0415 protein C7orf25 homolog OS=Bos taurus OX=9913 GN= PE=2 SV=1 CANONICAL=Q1LZE8-1" }, "locus": { "chromosome": "4", "start_pos": 78146866, "end_pos": 78145256, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000087497.2", "url": "https://www.ensembl.org/id/ENSBTAT00000087497.2" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000067673.1", "url": "https://www.ensembl.org/id/ENSBTAP00000067673.1" } ] } }, { "isoform_ac": "A0AAF6YTM4-1", "url": "https://www.uniprot.org/uniprotkb/A0AAF6YTM4/entry", "sequence": { "sequence": "MFKERNNAVSMSAHSMLCERIAIAKELIKRAESLSRSRKGGIEGGAKLCSKLKAELKFLQKVEAGKVAIKESHLQSTNLTHLRAIVESAENLEEVVSVLHVFGYTDTFGEKQTLVVDVVANGGHTWVKAIGRKAEALHNIWLGRGQYGDKSIIEQAEDFLQASHQQPVQYSNPHIIFAFYNSVSSPMAEKLKEMGISVRGDIVAVNSLLDHPEELQPSESESDDEGPELLQVTRVDRENILASVAFPTEIKVDVCKRVNLDITTLITYVSALSYGGCHFIFKEKVLTEQAEQERKEQVLPQLEAFMKDKELFACESAVKDFQSILDTLGGPGERERAAMLIKRINVVPDQPSERALKLVASSKINSRSLTIFGTGDNLKAITMTANSGFVRAANNQGVKFSVFIHQPRALTESKEALATPLPKDCTTDSEH", "length": 431, "header": "tr|A0AAF6YTM4-1|A0AAF6YTM4_BOVIN Computationally mapped isoform of Chromosome 4 C7orf25 homolog OS=Bos taurus OX=9913 GN=C4H7orf25 PE=3 SV=1 CANONICAL=Q1LZE8-1" }, "locus": { "chromosome": "4", "start_pos": 78146866, "end_pos": 78137061, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000012469.6", "url": "https://www.ensembl.org/id/ENSBTAT00000012469.6" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000012469.4", "url": "https://www.ensembl.org/id/ENSBTAP00000012469.4" } ] } }, { "isoform_ac": "Q1LZE8-1", "url": "https://www.uniprot.org/uniprotkb/Q1LZE8/entry#Q1LZE8-1", "sequence": { "sequence": "MSAHSMLCERIAIAKELIKRAESLSRSRKGGIEGGAKLCSKLKAELKFLQKVEAGKVAIKESHLQSTNLTHLRAIVESAENLEEVVSVLHVFGYTDTFGEKQTLVVDVVANGGHTWVKAIGRKAEALHNIWLGRGQYGDKSIIEQAEDFLQASHQQPVQYSNPHIIFAFYNSVSSPMAEKLKEMGISVRGDIVAVNSLLDHPEELQPSESESDDEGPELLQVTRVDRENILASVAFPTEIKVDVCKRVNLDITTLITYVSALSYGGCHFIFKEKVLTEQAEQERKEQVLPQLEAFMKDKELFACESAVKDFQSILDTLGGPGERERAAMLIKRINVVPDQPSERALKLVASSKINSRSLTIFGTGDNLKAITMTANSGFVRAANNQGVKFSVFIHQPRALTESKEALATPLPKDCTTDSEH", "length": 421, "header": "sp|Q1LZE8-1|CG025_BOVIN Isoform 1 of UPF0415 protein C7orf25 homolog OS=Bos taurus OX=9913 GN= PE=2 SV=1 CANONICAL=Q1LZE8-1" }, "locus": { "chromosome": "4", "start_pos": 78146866, "end_pos": 78145604, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000097135.1", "url": 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"id": "ENSBTAT00000076104.2", "url": "https://www.ensembl.org/id/ENSBTAT00000076104.2" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000069147.1", "url": "https://www.ensembl.org/id/ENSBTAP00000069147.1" } ] } }, { "isoform_ac": "Q2T9Z2-1", "url": "https://www.uniprot.org/uniprotkb/Q2T9Z2/entry#Q2T9Z2-1", "sequence": { "sequence": "MNFQVTGLGLDKIKLDSPQSFLDQEEVEEAEDGQLLEPEAWRTYVERRNALQEFLTSDLSPHLLKRHHARMELLKKCSYYIEILPKHLALGDQNPLVLPTTMFQLIDPWKFQRMKKVGAAQTKIQLLLLGDLLEQLDHGRSELDALLESPDPRPFLAGWGLVEQRLADLSAVMDSFLAMMVPGRLHIKHRLVSDIGATKIPHIRLMLSTKMPVMFDRKESVAHQDWVSLRWFVTIQQAVPEQFELRYKLLDPRTQQECMQCGIIPVAACAFDIRNLLPNRAYKFTVKRAESYTLVYEPWRDSLTLHTRPGPPEGLAPSRLGKLGLSLTTPSER", "length": 333, "header": "sp|Q2T9Z2-1|FND11_BOVIN Isoform 1 of Fibronectin type III domain-containing protein 11 OS=Bos taurus OX=9913 GN=FNDC11 PE=2 SV=1 CANONICAL=Q2T9Z2-1" }, "locus": { "chromosome": "13", "start_pos": 54116843, "end_pos": 54115845, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000039331.5", "url": "https://www.ensembl.org/id/ENSBTAT00000039331.5" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000042516.3", "url": "https://www.ensembl.org/id/ENSBTAP00000042516.3" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [ { "id": "bta:614565", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?bta:614565", "resource": "KEGG Pathway" } ], "orthologs": [ { "uniprot_canonical_ac": "A0A287AVG8-1", "protein_name": "Fibronectin type III domain containing 11", "gene_name": "FNDC11", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MNFQVSGLGLDNMKLDCPQSFLDQEEEAEEAEDQQLLEPEAWRTYVERRNALREFLTSDLSPHLLRRHHARMDLLRKCSYYIEILPKHLALGDQNPLVLPSAMFQLIDPWKFQRMKKLGTAQTKIQLLLLGDLLEQLDHGRSELDALLESPDPRPFLAGWGLVEQRLADLAAVMDSFLAMMVPGRLHIKHRLVSDVGAAKVPHIRLMLSTKMPVVFDRKASVAHQDWVSLRWFVTIQPAAAEQFELRFKLLDPRTQQERTQCGAIPVAACTVAVRNLLPNRSYRFTVKRAESYTLVYEPWRDSLTLQTRPGPPEGPAPGRLGKLSPPLPTPSER", "length": 334 }, "evidence": [ { "id": "Q2T9Z2", "url": "https://omabrowser.org/oma/group/Q2T9Z2/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "D4A0C8-1", "protein_name": "Fibronectin type III domain containing 11", "gene_name": "Fndc11", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MNFQVTGLALDKMKLDSPHSFLDSEEVEEAEDQQLLEPEAWRTFMERRNVLREFLTTDLSPQLLKRHHARMQLLKKCSYYIEILPKHLALGDQNPLVLPNTMFQLIDPWKFQRMKKVGTAQTKIQLLLLGDLLEQLDQGRAALDALLEAPDPRPFLAGWGLVEQQLADLTVVMDNFLAMMVPGHLHVKHRLVSDIGATKIPHIRLMLSTKMPVMFDRKESVAHQDWVSLRWFVTIQPAAPEQYELRFKLLEPRTQQECTQCGIVPVAACTFDVHNLLPNRTYKFTIKRAESYTLVYEPWRDSLTLQTTPGPPEGPAPSRLGKPSLPLTTPSER", "length": 333 }, "evidence": [ { "id": "Q2T9Z2", "url": "https://omabrowser.org/oma/group/Q2T9Z2/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "Q80WB0-1", "protein_name": "Fibronectin type III domain-containing protein 11", "gene_name": "Fndc11", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MNFQVTGLALDKMKLDSPHSFLDAEEVEEAEDQQLLEPEAWRTYMERRNVLREFLTTDLSPQLLKRHHARMQLLKKCSYYIEILPKHLALGDQNPLVLPNTMFQLIDPWKFQRMKKVGTAQTKIQLLLLGDLLEQLDHGRAALDALLEAPDPRPFLAGWGLVEQQLADLSVVMDNFLAMMVPGHLHVKHRLVSDIGATKIPHIRLMLSTKMPVMFDRKESVAHQDWVSLRWFVTIQPAAPEQYELRFKLLEPRTQQECTQCGIVPVAACTFDVHNLLPNRTYKFTIKRAESYTLVYEPWRDSLTLQTTPGPPEGPAPRLGEPPAGL", "length": 326 }, "evidence": [ { "id": "Q2T9Z2", "url": "https://omabrowser.org/oma/group/Q2T9Z2/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q9BVV2-1", "protein_name": "Fibronectin type III domain-containing protein 11", "gene_name": "FNDC11", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": 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"uniprot_canonical_ac": "Q2TBT8-1", "uniprot_ac": "Q2TBT8", "uniprot_id": "RN151_BOVIN", "mass": { "chemical_mass": 27318.0, "monoisotopic_mass": 27318.0 }, "refseq": { "ac": "NP_001070506", "name": "RING finger protein 151", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001070506" }, "gene_names": [ { "name": "RNF151", "type": "recommended", "evidence": [ { "id": "Q2TBT8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q2TBT8" } ] }, { "name": "RNF151", "type": "synonym", "evidence": [ { "id": "NP_001070506", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001070506" } ] } ], "protein_names": [ { "name": "RING finger protein 151", "type": "recommended", "evidence": [ { "id": "Q2TBT8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q2TBT8/entry#names_and_taxonomy" } ] }, { "name": "RING finger protein 151", "type": "synonym", "evidence": [ { "id": "NP_001070506", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001070506" } ] } ], "function": [], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Bos taurus", "taxid": 9913, "evidence": [ { "database": "UniProtKB", "id": "Q2TBT8", "url": "https://www.uniprot.org/uniprotkb/Q2TBT8" } ], "common_name": "Bovine", "glygen_name": "Bovine", "reference_species": "Bos taurus [9913]" } ], "gene": [ { "name": "RNF151", "url": "https://www.uniprot.org/uniprotkb/Q2TBT8", "locus": { "chromosome": "25", "start_pos": 1527393, "end_pos": 1521820, "strand": "-", "evidence": [ { "database": "Ensembl Gene", "id": "ENSBTAG00000009536", "url": "https://www.ensembl.org/id/ENSBTAG00000009536" } ] } } ], "crossref": [ { "id": "Q2TBT8", "url": "https://alphafold.ebi.ac.uk/entry/Q2TBT8", "database": "AlphaFoldDB", "categories": [] }, { "id": "ENSBTAG00000009536", "url": "https://bgee.org/?page=gene&gene_id=ENSBTAG00000009536", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "767973", "url": "https://www.ncbi.nlm.nih.gov/gene/767973", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR001293", "url": "https://www.ebi.ac.uk/interpro/entry/IPR001293", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR001841", "url": "https://www.ebi.ac.uk/interpro/entry/IPR001841", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR003613", "url": "https://www.ebi.ac.uk/interpro/entry/IPR003613", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR013010", "url": "https://www.ebi.ac.uk/interpro/entry/IPR013010", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR013083", "url": "https://www.ebi.ac.uk/interpro/entry/IPR013083", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR017907", "url": "https://www.ebi.ac.uk/interpro/entry/IPR017907", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "bta:767973", "url": "https://www.genome.jp/dbget-bin/www_bget?bta:767973", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "RSACHHI", "url": "https://omabrowser.org/oma/group/RSACHHI/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "A0A3Q1MK18", "url": "https://www.orthodb.org/?gene=A0A3Q1MK18", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "Q2TBT8", "url": "https://www.orthodb.org/?gene=Q2TBT8", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR10131", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR10131", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR10131:SF157", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR10131:SF157", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF13923", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF13923", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "NP_001070506", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001070506", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A3Q1MK18", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1MK18", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A3Q1MK18-1", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1MK18-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0AAA9T3H6", "url": "https://www.uniprot.org/uniprotkb/A0AAA9T3H6", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0AAA9T3H6-1", "url": "https://www.uniprot.org/uniprotkb/A0AAA9T3H6-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0AAF6ZGZ9", "url": "https://www.uniprot.org/uniprotkb/A0AAF6ZGZ9", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0AAF6ZGZ9-1", "url": "https://www.uniprot.org/uniprotkb/A0AAF6ZGZ9-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "Q2TBT8", "url": "https://www.uniprot.org/uniprotkb/Q2TBT8", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "Q2TBT8-1", "url": "https://www.uniprot.org/uniprotkb/Q2TBT8-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MSGGYDLNLFISPPDCNFLCSVCHGVLKRPVRLPCSHIFCKKCILRWLARQKTCPCCRKEVRHRKMVHVNKLQKIIGRLEVKCRNAEAGCQVTCPLAHRKGHQDSCPFELMVCPNEGCMLRVPRGALDEHRQNCQHGAYHRCSLGCGATLGPVERANHNCYRELREAWCQRQQRSRTLVLCLLQHMRKMHRTTGLIRRQLADFLEEDDPLLVGAPQEEAEATPEGSIGVEVWEPQGQATL", "length": 240, "header": "sp|Q2TBT8-1|RN151_BOVIN Isoform 1 of RING finger protein 151 OS=Bos taurus OX=9913 GN=RNF151 PE=2 SV=1 CANONICAL=Q2TBT8-1" }, "isoforms": [ { "isoform_ac": "A0A3Q1MK18-1", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1MK18/entry", "sequence": { "sequence": "MKWQLLSPGFSGAAVQTQIMSGGYDLNLFISPPDCNFLCSVCHGVLKRPVRLPCSHIFCKKCILRWLARQKTCPCCRKEVRHRKMVHVNKLQKIIGRLEVKCRNAEAGCQVTCPLAHRKGHQDSCPFELMVCPNEGCMLRVPRGALDEHRQNCQHGAYHRCSLGCGATLGPVERANHNCYRELREAWCQRQQRSRTLVLCLLQHMRKMHRTTGLIRRQLADFLEEDDPLLVGAPQEEAEATPEGSIGVEVWEPQGQATL", "length": 259, "header": "tr|A0A3Q1MK18-1|RN151_BOVIN Computationally mapped isoform of RING finger protein 151 OS=Bos taurus OX=9913 GN=RNF151 PE=2 SV=2 CANONICAL=Q2TBT8-1" }, "locus": { "chromosome": "25", "start_pos": 1527361, "end_pos": 1523323, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000078838.2", "url": "https://www.ensembl.org/id/ENSBTAT00000078838.2" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000071776.2", "url": "https://www.ensembl.org/id/ENSBTAP00000071776.2" } ] } }, { "isoform_ac": "A0AAA9T3H6-1", "url": "https://www.uniprot.org/uniprotkb/A0AAA9T3H6/entry", "sequence": { "sequence": "MAQMSGGYDLNLFISPPDCNFLCSVCHGVLKRPVRLPCSHIFCKKCILRWLARQKTCPCCRKEVRHRKMVHVNKLQKIIGRLEVKCRNAEAGCQVTCPLAHRKGHQDSCPFELMVCPNEGCMLRVPRGALDEHRQNCQHGAYHRCSLGCGATLGPVERANHNCYRELREAWCQRQQRSRTLVLCLLQHMRKMHRTTGLIRRQLADFLEEDDPLLVGAPQEEAEATPEGSIGVEVWEPQGQATL", "length": 243, "header": "tr|A0AAA9T3H6-1|RN151_BOVIN Computationally mapped isoform of RING finger protein 151 OS=Bos taurus OX=9913 GN=RNF151 PE=2 SV=1 CANONICAL=Q2TBT8-1" }, "locus": { "chromosome": "25", "start_pos": 1527361, "end_pos": 1522578, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000123875.1", "url": "https://www.ensembl.org/id/ENSBTAT00000123875.1" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000091024.1", "url": "https://www.ensembl.org/id/ENSBTAP00000091024.1" } ] } }, { "isoform_ac": "A0AAF6ZGZ9-1", "url": "https://www.uniprot.org/uniprotkb/A0AAF6ZGZ9/entry", "sequence": { "sequence": "IGGYDLNLFISPPDCNFLCSVCHGVLKRPVRLPCSHIFCKKCILRWLARQKTCPCCRKEVRHRKMVHVNKLQKIIGRLEVKCRNAEAGCQVTCPLAHRKGHQDSCPFELMVCPNEGCMLRVPRGALDEHRQNCQHGAYHRCSLGCGATLGPVERANHNCYRELREAWCQRQQRSRTLVLCLLQHMRKMHRTTGLIRRQLADFLEEDDPLLVGAPQEEAEATPEGSIGVEVWEPQGQATL", "length": 239, "header": "tr|A0AAF6ZGZ9-1|A0AAF6ZGZ9_BOVIN Computationally mapped isoform of Ring finger protein 151 OS=Bos taurus OX=9913 GN=RNF151 PE=4 SV=1 CANONICAL=Q2TBT8-1" }, "locus": { "chromosome": "25", "start_pos": 1527361, "end_pos": 1523681, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000047302.3", "url": "https://www.ensembl.org/id/ENSBTAT00000047302.3" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000044518.2", "url": "https://www.ensembl.org/id/ENSBTAP00000044518.2" } ] } }, { "isoform_ac": "Q2TBT8-1", "url": "https://www.uniprot.org/uniprotkb/Q2TBT8/entry#Q2TBT8-1", "sequence": { "sequence": "MSGGYDLNLFISPPDCNFLCSVCHGVLKRPVRLPCSHIFCKKCILRWLARQKTCPCCRKEVRHRKMVHVNKLQKIIGRLEVKCRNAEAGCQVTCPLAHRKGHQDSCPFELMVCPNEGCMLRVPRGALDEHRQNCQHGAYHRCSLGCGATLGPVERANHNCYRELREAWCQRQQRSRTLVLCLLQHMRKMHRTTGLIRRQLADFLEEDDPLLVGAPQEEAEATPEGSIGVEVWEPQGQATL", "length": 240, "header": "sp|Q2TBT8-1|RN151_BOVIN Isoform 1 of RING finger protein 151 OS=Bos taurus OX=9913 GN=RNF151 PE=2 SV=1 CANONICAL=Q2TBT8-1" }, "locus": {} } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [ { "id": "bta:767973", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?bta:767973", "resource": "KEGG Pathway" } ], "orthologs": [ { "uniprot_canonical_ac": "D3ZJQ8-1", "protein_name": "Ring finger protein 151", "gene_name": "Rnf151", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MSVHRCCQVQSPKPLVSVELPSRYRSCPPDCNFLCSVCHGVLKRPMRLPCSHIFCKKCIFQWLARQNTCPCCRKEVKRRKMVQVNKLRKTIGRLQVKCKNAAAGCLVTCPLAHRKGHQDSCPFELMACPNEGCTAQVLRGVLDEHRQHCQQNGQQRCPLGCGATLAALEGEQHNCYRELRDAWVQRHERNRTLLLNLLGRVRRVYRTTNLIRRQLAQLSNFLEDDTLLLNARVQETEVAPEPEMWGAQGQGVL", "length": 253 }, "evidence": [ { "id": "Q2TBT8", "url": "https://omabrowser.org/oma/group/Q2TBT8/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "Q2KHN1-1", "protein_name": "RING finger protein 151", "gene_name": "RNF151", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MGGGYDLNLFASPPDSNFVCSVCHGVLKRPARLPCSHIFCKKCILRWLARQKTCPCCRKEVKRKKVVHMNKLRKTIGRLEVKCKNADAGCIVTCPLAHRKGHQDSCPFELTACPNEGCTSQVPRGTLAEHRQHCQQGSQQRCPLGCGATLDPAERARHNCYRELHNAWSVRQERRRPLLLSLLRRVRWLDQATSVVRRELAELSNFLEEDTALLEGAPQEEAEAAPEGNVGAEVVGEPRANIPCK", "length": 245 }, "evidence": [ { "id": "Q2TBT8", "url": "https://omabrowser.org/oma/group/Q2TBT8/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "Q9CQ29-1", "protein_name": "RING finger protein 151", "gene_name": "Rnf151", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MSGGYDLNLFASPPDCKFLCSVCHGVLKRPTRLPCSHIFCKKCIFRWLARQNTCPCCRKEVTRRKMVEVNKLRKTIGRLQVKCKNAAAGCLDTHPLAHRKEHQDSCPFELMACPNEGCTVQVLRGVLDEHRQHCQQNGQQRCPLGCGSTLAALEGEHHNCYRELRDAWVQRHERNRTLLLGLLGRVRRVHLTTSIIHQQLAQLSNFLEDDDNLLLNAQVQETEVTPEAEMRGTQGQSVL", "length": 239 }, "evidence": [ { "id": "Q2TBT8", "url": "https://omabrowser.org/oma/group/Q2TBT8/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" } ], "go_annotation": { "categories": [ { "name": "Molecular Function", "total": 3, "go_terms": [ { "name": "zinc ion binding", "id": "GO:0008270", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008270", "evidence": [ { "database": "UniProtKB", "id": "Q2TBT8", "url": "https://www.uniprot.org/uniprotkb/Q2TBT8" } ], "pmid": "" }, { "name": "ubiquitin protein ligase activity", "id": "GO:0061630", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0061630", "evidence": [ { "database": "UniProtKB", "id": "Q2TBT8", "url": "https://www.uniprot.org/uniprotkb/Q2TBT8" } ], "pmid": "" }, { "name": "ubiquitin-protein transferase activity", "id": "GO:0004842", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0004842", "evidence": [ { "database": "UniProtKB", "id": "Q2TBT8", "url": "https://www.uniprot.org/uniprotkb/Q2TBT8" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 2, "go_terms": [ { "name": "protein ubiquitination", "id": "GO:0016567", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016567", "evidence": [ { "database": "UniProtKB", "id": "Q2TBT8", "url": "https://www.uniprot.org/uniprotkb/Q2TBT8" } ], "pmid": "" }, { "name": "ubiquitin-dependent protein catabolic process", "id": "GO:0006511", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006511", "evidence": [ { "database": "UniProtKB", "id": "Q2TBT8", "url": "https://www.uniprot.org/uniprotkb/Q2TBT8" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 1, "go_terms": [ { "name": "nucleus", "id": "GO:0005634", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005634", "evidence": [ { "database": "UniProtKB", "id": "Q2TBT8", "url": "https://www.uniprot.org/uniprotkb/Q2TBT8" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [ { "pdb_id": "AF-Q2TBT8-F1", "pdb_chain": "global", "start_pos": 1, "end_pos": 240, "overlap": "1.0", "method": "AlphaFold", "type": "alphafold", "resolution": -1.0, "url": "https://data.glygen.org/ln2downloads/pdb/current/AF-Q2TBT8-F1.pdb", "url_external": "https://alphafold.ebi.ac.uk/entry/Q2TBT8" } ], "lectin_list": [], "domain_list": [], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" }, { "name": "homologset.oma", "label": "OMA Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ], "tool_support": { "graph_view": "yes" } }, { "uniprot_canonical_ac": "Q17QQ9-1", "uniprot_ac": "Q17QQ9", "uniprot_id": "KRCC1_BOVIN", "mass": { "chemical_mass": 30704.0, "monoisotopic_mass": 30704.0 }, "refseq": { "ac": "NP_001068771", "name": "lysine-rich coiled-coil protein 1", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001068771" }, "gene_names": [ { "name": "KRCC1", "type": "recommended", "evidence": [ { "id": "Q17QQ9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q17QQ9" } ] }, { "name": "KRCC1", "type": "synonym", "evidence": [ { "id": "NP_001068771", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001068771" } ] } ], "protein_names": [ { "name": "Lysine-rich coiled-coil protein 1", "type": "recommended", "evidence": [ { "id": "Q17QQ9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q17QQ9/entry#names_and_taxonomy" } ] }, { "name": "lysine-rich coiled-coil protein 1", "type": "synonym", "evidence": [ { "id": "NP_001068771", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001068771" } ] } ], "function": [ { "annotation": "Regulates CHEK1-mediated cell cycle checkpoint. Facilitates efficient recombination and homologous recombination repair. Required for proper S-phase progression and mitotic entry.", "evidence": [ { "database": "UniProtKB", "id": "Q17QQ9", "url": "https://www.uniprot.org/uniprotkb/Q17QQ9#function" }, { "database": "UniProtKB", "id": "Q9NPI7", "url": "https://www.uniprot.org/uniprotkb/Q9NPI7#function" }, { "database": "UniProtKB", "id": "A0A3Q1MNC8", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1MNC8#function" }, { "database": "UniProtKB", "id": "ARBA00094492", "url": "https://www.uniprot.org/uniprotkb/ARBA00094492#function" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Bos taurus", "taxid": 9913, "evidence": [ { "database": "UniProtKB", "id": "Q17QQ9", "url": "https://www.uniprot.org/uniprotkb/Q17QQ9" } ], "common_name": "Bovine", "glygen_name": "Bovine", "reference_species": "Bos taurus [9913]" } ], "gene": [ { "name": "KRCC1", "url": "https://www.uniprot.org/uniprotkb/Q17QQ9", "locus": { "chromosome": "11", "start_pos": 48008308, "end_pos": 47993581, "strand": "-", "evidence": [ { "database": "Ensembl Gene", "id": "ENSBTAG00000002542", "url": "https://www.ensembl.org/id/ENSBTAG00000002542" } ] } } ], "crossref": [ { "id": "Q17QQ9", "url": "https://alphafold.ebi.ac.uk/entry/Q17QQ9", "database": "AlphaFoldDB", "categories": [] }, { "id": "ENSBTAG00000002542", "url": "https://bgee.org/?page=gene&gene_id=ENSBTAG00000002542", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "507166", "url": "https://www.ncbi.nlm.nih.gov/gene/507166", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "bta:507166", "url": "https://www.genome.jp/dbget-bin/www_bget?bta:507166", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "A0A3Q1MNC8", "url": "https://www.orthodb.org/?gene=A0A3Q1MNC8", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "Q17QQ9", "url": "https://www.orthodb.org/?gene=Q17QQ9", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR46742", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR46742", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR46742:SF3", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR46742:SF3", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "NP_001068771", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001068771", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A3Q1MNC8", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1MNC8", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A3Q1MNC8-1", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1MNC8-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "Q17QQ9", "url": "https://www.uniprot.org/uniprotkb/Q17QQ9", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "Q17QQ9-1", "url": "https://www.uniprot.org/uniprotkb/Q17QQ9-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MKHSKKTYDSFQDELEDYIKVQKARGLEPKTCFRKMREDYLETYGYKEEVDSRPRCRMFEQRLPYGTVQTYPRSCSISQRVEKQLPQWLPAHDSRLRLDSLSYSQFTRDCFSGKPVPPNLSQHESNCSSYSVESGVYRHLSSENNTSAHQASYKHIHQKRKRHTEEGREKPEEERPKHKRKKACEEIDLDKYKSIQTSKTEAETVRVSTEKLKNRKEKRSRDVASKKEERKRRKEKKEQGQERTEEEMLWDQSILGF", "length": 257, "header": "sp|Q17QQ9-1|KRCC1_BOVIN Isoform 1 of Lysine-rich coiled-coil protein 1 OS=Bos taurus OX=9913 GN=KRCC1 PE=2 SV=1 CANONICAL=Q17QQ9-1" }, "isoforms": [ { "isoform_ac": "A0A3Q1MNC8-1", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1MNC8/entry", "sequence": { "sequence": "MDVESLVKLMKHSKKTYDSFQDELEDYIKVQKARGLEPKTCFRKMREDYLETYGYKEEVDSRPRCRMFEQRLPYGTVQTYPRSCSISQRVEKQLPQWLPAHDSRLRLDSLSYSQFTRDCFSGKPVPPNLSQHESNCSSYSVESGVYRHLSSENNTSAHQASYKHIHQKRKRHTEEGREKPEEERPKHKRKKACEEIDLDKYKSIQTSKTEAETVRVSTEKLKNRKEKRSRDVASKKEERKRRKEKKEQGQERTEEEMLWDQSILGF", "length": 266, "header": "tr|A0A3Q1MNC8-1|KRCC1_BOVIN Computationally mapped isoform of Lysine-rich coiled-coil protein 1 OS=Bos taurus OX=9913 GN=KRCC1 PE=2 SV=1 CANONICAL=Q17QQ9-1" }, "locus": { "chromosome": "11", "start_pos": 48007597, "end_pos": 48006827, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000078504.1", "url": "https://www.ensembl.org/id/ENSBTAT00000078504.1" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000073424.1", "url": "https://www.ensembl.org/id/ENSBTAP00000073424.1" } ] } }, { "isoform_ac": "Q17QQ9-1", "url": "https://www.uniprot.org/uniprotkb/Q17QQ9/entry#Q17QQ9-1", "sequence": { "sequence": "MKHSKKTYDSFQDELEDYIKVQKARGLEPKTCFRKMREDYLETYGYKEEVDSRPRCRMFEQRLPYGTVQTYPRSCSISQRVEKQLPQWLPAHDSRLRLDSLSYSQFTRDCFSGKPVPPNLSQHESNCSSYSVESGVYRHLSSENNTSAHQASYKHIHQKRKRHTEEGREKPEEERPKHKRKKACEEIDLDKYKSIQTSKTEAETVRVSTEKLKNRKEKRSRDVASKKEERKRRKEKKEQGQERTEEEMLWDQSILGF", "length": 257, "header": "sp|Q17QQ9-1|KRCC1_BOVIN Isoform 1 of Lysine-rich coiled-coil protein 1 OS=Bos taurus OX=9913 GN=KRCC1 PE=2 SV=1 CANONICAL=Q17QQ9-1" }, "locus": { "chromosome": "11", "start_pos": 48007597, "end_pos": 48006827, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000103601.1", "url": "https://www.ensembl.org/id/ENSBTAT00000103601.1" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000102672.1", "url": "https://www.ensembl.org/id/ENSBTAP00000102672.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [ { "id": "bta:507166", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?bta:507166", "resource": "KEGG Pathway" } ], "orthologs": [], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 1, "go_terms": [ { "name": "nucleus", "id": "GO:0005634", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005634", "evidence": [ { "database": "UniProtKB", "id": "Q17QQ9", "url": "https://www.uniprot.org/uniprotkb/Q17QQ9" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 1, "go_terms": [ { "name": "DNA damage response", "id": "GO:0006974", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006974", "evidence": [ { "database": "UniProtKB", "id": "Q17QQ9", "url": "https://www.uniprot.org/uniprotkb/Q17QQ9" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 119, "end_pos": 121, "annotation": "n_glycosylation_sequon" }, { "start_pos": 126, "end_pos": 128, "annotation": "n_glycosylation_sequon" }, { "start_pos": 144, "end_pos": 146, "annotation": "n_glycosylation_sequon" }, { "start_pos": 145, "end_pos": 147, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [ { "pdb_id": "AF-Q17QQ9-F1", "pdb_chain": "global", "start_pos": 1, "end_pos": 257, "overlap": "1.0", "method": "AlphaFold", "type": "alphafold", "resolution": -1.0, "url": "https://data.glygen.org/ln2downloads/pdb/current/AF-Q17QQ9-F1.pdb", "url_external": "https://alphafold.ebi.ac.uk/entry/Q17QQ9" } ], "lectin_list": [], "domain_list": [], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 119, "end_pos": 121 }, { "start_pos": 126, "end_pos": 128 }, { "start_pos": 144, "end_pos": 146 }, { "start_pos": 145, "end_pos": 147 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ], "tool_support": { "graph_view": "yes" } }, { "uniprot_canonical_ac": "Q2M2U5-1", "uniprot_ac": "Q2M2U5", "uniprot_id": "IQCF2_BOVIN", "mass": { "chemical_mass": 19535.0, "monoisotopic_mass": 19535.0 }, "refseq": { "ac": "NP_001071412", "name": "IQ domain-containing protein F2", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001071412" }, "gene_names": [ { "name": "IQCF2", "type": "recommended", "evidence": [ { "id": "Q2M2U5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q2M2U5" } ] }, { "name": "IQCF2", "type": "synonym", "evidence": [ { "id": "NP_001071412", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001071412" } ] } ], "protein_names": [ { "name": "IQ domain-containing protein F2", "type": "recommended", "evidence": [ { "id": "Q2M2U5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q2M2U5/entry#names_and_taxonomy" } ] }, { "name": "IQ domain-containing protein F2", "type": "synonym", "evidence": [ { "id": "NP_001071412", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001071412" } ] }, { "name": "IQ motif containing F4", "type": "synonym", "evidence": [ { "id": "NP_001071412", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001071412" } ] } ], "function": [], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Bos taurus", "taxid": 9913, "evidence": [ { "database": "UniProtKB", "id": "Q2M2U5", "url": "https://www.uniprot.org/uniprotkb/Q2M2U5" } ], "common_name": "Bovine", "glygen_name": "Bovine", "reference_species": "Bos taurus [9913]" } ], "gene": [ { "name": "IQCF2", "url": "https://www.uniprot.org/uniprotkb/Q2M2U5", "locus": { "chromosome": "22", "start_pos": 49024703, "end_pos": 49034616, "strand": "+", "evidence": [ { "database": "Ensembl Gene", "id": "ENSBTAG00000032279", "url": "https://www.ensembl.org/id/ENSBTAG00000032279" } ] } } ], "crossref": [ { "id": "Q2M2U5", "url": "https://alphafold.ebi.ac.uk/entry/Q2M2U5", "database": "AlphaFoldDB", "categories": [] }, { "id": "ENSBTAG00000032279", "url": "https://bgee.org/?page=gene&gene_id=ENSBTAG00000032279", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "521051", "url": "https://www.ncbi.nlm.nih.gov/gene/521051", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR000048", "url": "https://www.ebi.ac.uk/interpro/entry/IPR000048", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR039887", "url": "https://www.ebi.ac.uk/interpro/entry/IPR039887", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "bta:521051", "url": "https://www.genome.jp/dbget-bin/www_bget?bta:521051", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "WWRMTLL", "url": "https://omabrowser.org/oma/group/WWRMTLL/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "A0A3Q1MPD5", "url": "https://www.orthodb.org/?gene=A0A3Q1MPD5", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A452DJC1", "url": "https://www.orthodb.org/?gene=A0A452DJC1", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "Q2M2U5", "url": "https://www.orthodb.org/?gene=Q2M2U5", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR21633", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR21633", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR21633:SF4", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR21633:SF4", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00612", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00612", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "NP_001071412", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001071412", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A3Q1MPD5", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1MPD5", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A3Q1MPD5-1", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1MPD5-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A452DJC1", "url": "https://www.uniprot.org/uniprotkb/A0A452DJC1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A452DJC1-1", "url": "https://www.uniprot.org/uniprotkb/A0A452DJC1-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "Q2M2U5", "url": "https://www.uniprot.org/uniprotkb/Q2M2U5", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "Q2M2U5-1", "url": "https://www.uniprot.org/uniprotkb/Q2M2U5-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MGVRFCKDGHVIQIIIENKEEVTMKKMKEQQKKREKTKNGRRVIAAKKIQAWWRGTLVRRTLLHAALSTWIIQSWWRLTKDRLLQKKRRAALSDYALRERAVVKLQSLVRMWRIHWRYCQVLNAIYVIQCHWQCHNCQTCALLRGHCVVTATHLQFHIEIINP", "length": 163, "header": "sp|Q2M2U5-1|IQCF2_BOVIN Isoform 1 of IQ domain-containing protein F2 OS=Bos taurus OX=9913 GN=IQCF2 PE=2 SV=1 CANONICAL=Q2M2U5-1" }, "isoforms": [ { "isoform_ac": "A0A3Q1MPD5-1", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1MPD5/entry", "sequence": { "sequence": "MWTGLTGGMKDGHVIQIIIENKEEVTMKKMKEQQKKKEKTKNGRRVIAAKKIQAWWRGTLVRRTLLHAALSTWIIQSWWRLTKDRLLQKKRRAALSDYALRERAVVKLQSLVRMWRIHWRYCQVLNAIYVIQCHWQCHNCQTCALLRGHCVVTATHLQFHIEIINP", "length": 166, "header": "tr|A0A3Q1MPD5-1|IQCF2_BOVIN Computationally mapped isoform of IQ domain-containing protein F2 OS=Bos taurus OX=9913 GN=IQCF2 PE=2 SV=2 CANONICAL=Q2M2U5-1" }, "locus": { "chromosome": "22", "start_pos": 49026467, "end_pos": 49024762, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000075896.2", "url": "https://www.ensembl.org/id/ENSBTAT00000075896.2" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000071516.2", "url": "https://www.ensembl.org/id/ENSBTAP00000071516.2" } ] } }, { "isoform_ac": "A0A452DJC1-1", "url": "https://www.uniprot.org/uniprotkb/A0A452DJC1/entry", "sequence": { "sequence": "MGVRFCKDGHVIQIIIENKEEVTMKKMKEQQKKKEKTKNGRRVIAAKKIQAWWRGTLVRRTLLHAALSTWIIQSWWRLTKDRLLQKKRRAALSDYALRERAVVKLQSLVRMWRIHWRYCQVLNAIYVIQCHWQCHNCQTCALLRGHCVVTATHLQFHIEIINP", "length": 163, "header": "tr|A0A452DJC1-1|IQCF2_BOVIN Computationally mapped isoform of IQ domain-containing protein F2 OS=Bos taurus OX=9913 GN=IQCF2 PE=2 SV=1 CANONICAL=Q2M2U5-1" }, "locus": { "chromosome": "22", "start_pos": 49026178, "end_pos": 49024762, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000045775.2", "url": "https://www.ensembl.org/id/ENSBTAT00000045775.2" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000043137.2", "url": "https://www.ensembl.org/id/ENSBTAP00000043137.2" } ] } }, { "isoform_ac": "Q2M2U5-1", "url": "https://www.uniprot.org/uniprotkb/Q2M2U5/entry#Q2M2U5-1", "sequence": { "sequence": "MGVRFCKDGHVIQIIIENKEEVTMKKMKEQQKKREKTKNGRRVIAAKKIQAWWRGTLVRRTLLHAALSTWIIQSWWRLTKDRLLQKKRRAALSDYALRERAVVKLQSLVRMWRIHWRYCQVLNAIYVIQCHWQCHNCQTCALLRGHCVVTATHLQFHIEIINP", "length": 163, "header": "sp|Q2M2U5-1|IQCF2_BOVIN Isoform 1 of IQ domain-containing protein F2 OS=Bos taurus OX=9913 GN=IQCF2 PE=2 SV=1 CANONICAL=Q2M2U5-1" }, "locus": {} } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [ { "id": "bta:521051", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?bta:521051", "resource": "KEGG Pathway" } ], "orthologs": [ { "uniprot_canonical_ac": "A0A8V1A940-1", "protein_name": "IQ motif containing F6", "gene_name": "IQCF6", "tax_id": 9031, "organism": "Gallus gallus", "sequence": { "sequence": "MGPMETQIDPDTAAAMAIQAWWRGQLVRRALLVAASSARRIQGWWRRVGSQRREQQRLWVLAEYIKLERAVVLLQAQVRAWVMRTEYKRCREAARTIQTCWRGYVQRRASNCTKDVDLHIDIVLGVPGDCGDQSE", "length": 135 }, "evidence": [ { "id": "Q2M2U5", "url": "https://omabrowser.org/oma/group/Q2M2U5/", "database": "OMA" } ], "glygen_name": "Chicken", "common_name": "Chicken" }, { "uniprot_canonical_ac": "Q6AXX0-1", "protein_name": "IQ domain-containing protein F3", "gene_name": "Iqcf3", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MELDQDQKVETPEAAENGKDEMQLEEQTQDEDTTETETETETETEAEAEGADGTILERTESVKAKLVPQAEKQIQDEKTGIKEADRAIQEQTQDDETEAEGADGAILKRSESVKVKLIPQAEKQIQDEKTGIKEADRAIQELPANAELAGVKIQAWWRGTLVRRTLLLAILSAWTIQSWWKETKSRLQGRKLHDVMRCRLRNLNLKSISRRKRPNQSSFL", "length": 220 }, "evidence": [ { "id": "Q2M2U5", "url": "https://omabrowser.org/oma/group/Q2M2U5/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "Q8IXL9-1", "protein_name": "IQ domain-containing protein F2", "gene_name": "IQCF2", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MRVRFCTKGNLILVIIEDVEESIEWKTLQKKKQQKIKEKLRIRTKAAVKIQAWWRGTLVRRTLLHAALRAWIIQCWWRMTLSRVLEKKRQAALIAYATRERAVIKLQSLVRMWRVRWRYCQVLNAIYIIQGHWQCHNCQTCALLQGHCVVTATHLQFHIEIINS", "length": 164 }, "evidence": [ { "id": "Q2M2U5", "url": "https://omabrowser.org/oma/group/Q2M2U5/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" } ], "go_annotation": { "categories": [ { "name": "Molecular Function", "total": 1, "go_terms": [ { "name": "calmodulin binding", "id": "GO:0005516", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005516", "evidence": [ { "database": "UniProtKB", "id": "Q2M2U5", "url": "https://www.uniprot.org/uniprotkb/Q2M2U5" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [ { "pdb_id": "AF-Q2M2U5-F1", "pdb_chain": "global", "start_pos": 1, "end_pos": 163, "overlap": "1.0", "method": "AlphaFold", "type": "alphafold", "resolution": -1.0, "url": "https://data.glygen.org/ln2downloads/pdb/current/AF-Q2M2U5-F1.pdb", "url_external": "https://alphafold.ebi.ac.uk/entry/Q2M2U5" } ], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "Q2M2U5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q2M2U5" }, { "id": "PRU00116", "database": "PROSITE", "url": "https://prosite.expasy.org/PRU00116" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "IQ 1", "eco_id": "ECO_0000255", "start_pos": 42, "end_pos": 71, "start_aa": "Arg", "end_aa": "Ile", "glycosite_overlap": [] }, { "evidence": [ { "id": "Q2M2U5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q2M2U5" }, { "id": "PRU00116", "database": "PROSITE", "url": "https://prosite.expasy.org/PRU00116" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "IQ 2", "eco_id": "ECO_0000255", "start_pos": 98, "end_pos": 127, "start_aa": "Arg", "end_aa": "Val", "glycosite_overlap": [] } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" }, { "name": "homologset.oma", "label": "OMA Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ], "tool_support": { "graph_view": "yes" } }, { "uniprot_canonical_ac": "G5E643-1", "uniprot_ac": "G5E643", "uniprot_id": "G5E643_BOVIN", "mass": { "chemical_mass": 41541.0, "monoisotopic_mass": 41541.0 }, "refseq": {}, "gene_names": [ { "name": "AS3MT", "type": "recommended", "evidence": [ { "id": "G5E643", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G5E643" } ] } ], "protein_names": [ { "name": "Arsenite methyltransferase", "type": "recommended", "evidence": [ { "id": "G5E643", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G5E643/entry#names_and_taxonomy" } ] }, { "name": "2.1.1.137", "type": "synonym", "evidence": [ { "id": "G5E643", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G5E643/entry#names_and_taxonomy" } ] } ], "function": [], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Bos taurus", "taxid": 9913, "evidence": [ { "database": "UniProtKB", "id": "G5E643", "url": "https://www.uniprot.org/uniprotkb/G5E643" } ], "common_name": "Bovine", "glygen_name": "Bovine", "reference_species": "Bos taurus [9913]" } ], "gene": [ { "name": "AS3MT", "url": "https://www.uniprot.org/uniprotkb/G5E643", "locus": { "chromosome": "26", "start_pos": 23520281, "end_pos": 23502762, "strand": "-", "evidence": [ { "database": "Ensembl Gene", "id": "ENSBTAG00000036127", "url": "https://www.ensembl.org/id/ENSBTAG00000036127" } ] } } ], "crossref": [ { "id": "G5E643", "url": "https://alphafold.ebi.ac.uk/entry/G5E643", "database": "AlphaFoldDB", "categories": [] }, { "id": "ENSBTAG00000036127", "url": "https://bgee.org/?page=gene&gene_id=ENSBTAG00000036127", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "cd02440", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd02440", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "IPR025714", "url": "https://www.ebi.ac.uk/interpro/entry/IPR025714", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR026669", "url": "https://www.ebi.ac.uk/interpro/entry/IPR026669", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR029063", "url": "https://www.ebi.ac.uk/interpro/entry/IPR029063", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "A0A3Q1N140", "url": "https://www.orthodb.org/?gene=A0A3Q1N140", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "G5E643", "url": "https://www.orthodb.org/?gene=G5E643", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR43675", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR43675", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR43675:SF8", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR43675:SF8", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF13847", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF13847", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "R-BTA-156581", "url": "https://www.reactome.org/PathwayBrowser/#R-BTA-156581", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "69432", "url": "https://www.rhea-db.org/rhea/69432", "database": "Rhea", "categories": [ "Enzyme and Pathway" ] }, { "id": "69460", "url": "https://www.rhea-db.org/rhea/69460", "database": "Rhea", "categories": [ "Enzyme and Pathway" ] }, { "id": "69464", "url": "https://www.rhea-db.org/rhea/69464", "database": "Rhea", "categories": [ "Enzyme and Pathway" ] }, { "id": "A0A3Q1N140", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1N140", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A3Q1N140-1", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1N140-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "G5E643", "url": "https://www.uniprot.org/uniprotkb/G5E643", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "G5E643-1", "url": "https://www.uniprot.org/uniprotkb/G5E643-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MATPRDAEIRKDVQTYYGQVLKKSADFQTNACVTAARPVPQHIREALQNVHEEVSLRYYGCGLVIPECLENCWILDLGSGSGRDCYALSQLVGEKGHVTGIDMTEGQVEVANKYIEYHMEKYGFQAPNVTFIHGYIEKLEEAGIKNESYDIVISNCAINLVPDKQQVLQEVYRVLKYGGELYFSDVYASLELPEEIRTHKVLWGECLGGALYWKDLSILAKKVGFCPPRLVTANFITVQNKELENVIGDCRFVSATFRLFKLPKTGPTQKCQVIYNGGIRGHEKELIFDANFTFKKDEVVEVDEETVAILKNSRFAQDFLIGPDGEKFPTCGAYTALEDVVTDPFELAGRSDSAESRSFPAVGGCCSTKKCS", "length": 372, "header": "tr|G5E643-1|G5E643_BOVIN Isoform 1 of Arsenite methyltransferase OS=Bos taurus OX=9913 GN=AS3MT PE=3 SV=2 CANONICAL=G5E643-1" }, "isoforms": [ { "isoform_ac": "A0A3Q1N140-1", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1N140/entry", "sequence": { "sequence": "MATPRDAEIRKDVQTYYGQVLKKSADFQTNACVTAARPVPQHIREALQNVHEEVSLRYYGCGLVIPECLENCWILDLGSGSGRDCYALSQLVGEKGHVTGIDMTEGQVEVANKYIEYHMEKYGFQAPNVTFIHGYIEKLEEAGIKNESYDIVISNCAINLVPDKQQVLQEVYRVLKYGGELYFSDVYASLELPEEIRTHKVLWGECLGGALYWKDLSILAKKVGFCPPRLVTANFITVQNKELENVIGDCRFVSATFRLFKLPKTGPTQKCQVIYNGGIRGHEKELIFDANFTFKKDEVVEVDEETVAILKNSRFAQDFLIGPDGEKFPTCGAYTALEVKMMVGRHHRFNGHEFEQTPGDSEGQGSLACYSSWDHKESDMTE", "length": 382, "header": "tr|A0A3Q1N140-1|G5E643_BOVIN Computationally mapped isoform of Arsenite methyltransferase OS=Bos taurus OX=9913 GN=AS3MT PE=3 SV=2 CANONICAL=G5E643-1" }, "locus": { "chromosome": "26", "start_pos": 23513630, "end_pos": 23502809, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000069974.3", "url": "https://www.ensembl.org/id/ENSBTAT00000069974.3" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000062630.2", "url": "https://www.ensembl.org/id/ENSBTAP00000062630.2" } ] } }, { "isoform_ac": "G5E643-1", "url": "https://www.uniprot.org/uniprotkb/G5E643/entry", "sequence": { "sequence": "MATPRDAEIRKDVQTYYGQVLKKSADFQTNACVTAARPVPQHIREALQNVHEEVSLRYYGCGLVIPECLENCWILDLGSGSGRDCYALSQLVGEKGHVTGIDMTEGQVEVANKYIEYHMEKYGFQAPNVTFIHGYIEKLEEAGIKNESYDIVISNCAINLVPDKQQVLQEVYRVLKYGGELYFSDVYASLELPEEIRTHKVLWGECLGGALYWKDLSILAKKVGFCPPRLVTANFITVQNKELENVIGDCRFVSATFRLFKLPKTGPTQKCQVIYNGGIRGHEKELIFDANFTFKKDEVVEVDEETVAILKNSRFAQDFLIGPDGEKFPTCGAYTALEDVVTDPFELAGRSDSAESRSFPAVGGCCSTKKCS", "length": 372, "header": "tr|G5E643-1|G5E643_BOVIN Isoform 1 of Arsenite methyltransferase OS=Bos taurus OX=9913 GN=AS3MT PE=3 SV=2 CANONICAL=G5E643-1" }, "locus": { "chromosome": "26", "start_pos": 23519704, "end_pos": 23502809, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000050619.4", "url": "https://www.ensembl.org/id/ENSBTAT00000050619.4" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000047294.3", "url": "https://www.ensembl.org/id/ENSBTAP00000047294.3" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [ "enzyme" ], "publication": [], "pathway": [ { "id": "R-BTA-156581", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-BTA-156581", "resource": "Reactome", "description": "Methylation" } ], "orthologs": [], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 1, "go_terms": [ { "name": "cytosol", "id": "GO:0005829", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005829", "evidence": [ { "database": "UniProtKB", "id": "G5E643", "url": "https://www.uniprot.org/uniprotkb/G5E643" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 3, "go_terms": [ { "name": "toxin metabolic process", "id": "GO:0009404", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0009404", "evidence": [ { "database": "UniProtKB", "id": "G5E643", "url": "https://www.uniprot.org/uniprotkb/G5E643" } ], "pmid": "" }, { "name": "arsonoacetate metabolic process", "id": "GO:0018872", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0018872", "evidence": [ { "database": "UniProtKB", "id": "G5E643", "url": "https://www.uniprot.org/uniprotkb/G5E643" } ], "pmid": "" }, { "name": "methylation", "id": "GO:0032259", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0032259", "evidence": [ { "database": "UniProtKB", "id": "G5E643", "url": "https://www.uniprot.org/uniprotkb/G5E643" } ], "pmid": "" } ] }, { "name": "Molecular Function", "total": 1, "go_terms": [ { "name": "arsenite methyltransferase activity", "id": "GO:0030791", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030791", "evidence": [ { "database": "UniProtKB", "id": "G5E643", "url": "https://www.uniprot.org/uniprotkb/G5E643" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 128, "end_pos": 130, "annotation": "n_glycosylation_sequon" }, { "start_pos": 146, "end_pos": 148, "annotation": "n_glycosylation_sequon" }, { "start_pos": 291, "end_pos": 293, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [ { "id": "69432", "name": "", "equation": "arsenic triglutathione + 3 [thioredoxin]-dithiol + 3 S-adenosyl-L-methionine = trimethylarsine + 3 [thioredoxin]-disulfide + 3 glutathione + 3 S-adenosyl-L-homocysteine + 3 H(+)", "summary": "", "cellular_location": "", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [ "G5E643-1" ], "evidence": [ { "id": "69432", "database": "Rhea", "url": "https://www.rhea-db.org/rhea/69432" } ] }, { "id": "69460", "name": "", "equation": "arsenic triglutathione + [thioredoxin]-dithiol + S-adenosyl-L-methionine + 2 H2O = methylarsonous acid + [thioredoxin]-disulfide + 3 glutathione + S-adenosyl-L-homocysteine + H(+)", "summary": "", "cellular_location": "", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [ "G5E643-1" ], "evidence": [ { "id": "69460", "database": "Rhea", "url": "https://www.rhea-db.org/rhea/69460" } ] }, { "id": "69464", "name": "", "equation": "arsenic triglutathione + 2 [thioredoxin]-dithiol + 2 S-adenosyl-L-methionine + H2O = dimethylarsinous acid + 2 [thioredoxin]-disulfide + 3 glutathione + 2 S-adenosyl-L-homocysteine + 2 H(+)", "summary": "", "cellular_location": "", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [ "G5E643-1" ], "evidence": [ { "id": "69464", "database": "Rhea", "url": "https://www.rhea-db.org/rhea/69464" } ] }, { "id": "R-BTA-5696213", "name": "AS3MT transfers CH3 from AdoMet to methylarsonite", "equation": "", "summary": "This event has been computationally inferred from an event that has been demonstrated in another species.

The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.

More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "cellular_location": "cytosol", "input_participant_list": [ "R-ALL-5696224" ], "output_participant_list": [ "R-ALL-5696211" ], "enzyme_list": [ "G5E643-1" ], "evidence": [ { "id": "R-BTA-5696213", "database": "Reactome", "url": "https://www.reactome.org/PathwayBrowser/#R-BTA-5696213" } ] }, { "id": "R-BTA-5696220", "name": "AS3MT transfers CH3 from AdoMet to arsenite(3-)", "equation": "", "summary": "This event has been computationally inferred from an event that has been demonstrated in another species.

The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.

More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "cellular_location": "cytosol", "input_participant_list": [ "R-ALL-5696216" ], "output_participant_list": [], "enzyme_list": [ "G5E643-1" ], "evidence": [ { "id": "R-BTA-5696220", "database": "Reactome", "url": "https://www.reactome.org/PathwayBrowser/#R-BTA-5696220" } ] } ], "reaction_participants": [ { "participant_id": "R-ALL-5696211", "participant_name": "dimethylarsinate [cytosol]", "crossref": [ { "id": "C07308", "database": "COMPOUND", "url": "" }, { "id": "16223", "database": "ChEBI", "url": "" } ] }, { "participant_id": "R-ALL-5696216", "participant_name": "arsenite(3-) [cytosol]", "crossref": [ { "id": "29242", "database": "ChEBI", "url": "" }, { "id": "C06697", "database": "KEGG Gene", "url": "" }, { "id": "CPD-763", "database": "AraCyc", "url": "" }, { "id": "6857431", "database": "PubChem Compound", "url": "" } ] }, { "participant_id": "R-ALL-5696224", "participant_name": "methylarsonite [cytosol]", "crossref": [ { "id": "14597", "database": "ChEBI", "url": "" } ] } ], "reaction_enzymes": [ { "uniprot_ac": "G5E643", "gene_name": "AS3MT", "activity": [ { "ec_number": "2.1.1.137", "activity": "arsenic triglutathione + 3 [thioredoxin]-dithiol + 3 S-adenosyl-L-methionine = trimethylarsine + 3 [thioredoxin]-disulfide + 3 glutathione + 3 S-adenosyl-L-homocysteine + 3 H(+).", "evidence": [ { "id": "G5E643", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G5E643" } ] }, { "ec_number": "2.1.1.137", "activity": "", "evidence": [ { "id": "G5E643", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G5E643" } ] } ] } ], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "G5E643", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G5E643" }, { "id": "PF13847", "database": "Pfam", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF13847" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "Methyltransferase", "eco_id": "ECO_0000259", "start_pos": 71, "end_pos": 217, "start_aa": "Asn", "end_aa": "Ser", "glycosite_overlap": [] } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [ { "ec_number": "2.1.1.137", "ec_name": "arsenic triglutathione + 3 [thioredoxin]-dithiol + 3 S-adenosyl-L-methionine = trimethylarsine + 3 [thioredoxin]-disulfide + 3 glutathione + 3 S-adenosyl-L-homocysteine + 3 H(+).", "evidence": [ { "id": "2.1.1.137", "database": "Rhea", "url": "https://www.rhea-db.org/rhea/?query=ec:2.1.1.137" }, { "id": "2.1.1.137", "database": "BRENDA Enzymes", "url": "https://www.brenda-enzymes.org/enzyme.php?ecno=2.1.1.137" } ] } ], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 128, "end_pos": 130 }, { "start_pos": 146, "end_pos": 148 }, { "start_pos": 291, "end_pos": 293 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ], "tool_support": { "graph_view": "yes" } }, { "uniprot_canonical_ac": "Q32LN3-1", "uniprot_ac": "Q32LN3", "uniprot_id": "PDCL2_BOVIN", "mass": { "chemical_mass": 28013.0, "monoisotopic_mass": 28013.0 }, "refseq": { "ac": "NP_001035641", "name": "phosducin-like protein 2", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001035641" }, "gene_names": [ { "name": "PDCL2", "type": "recommended", "evidence": [ { "id": "Q32LN3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q32LN3" } ] }, { "name": "PDCL2", "type": "synonym", "evidence": [ { "id": "NP_001035641", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001035641" } ] } ], "protein_names": [ { "name": "Phosducin-like protein 2", "type": "recommended", "evidence": [ { "id": "Q32LN3", "database": "UniProtKB", "url": 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"https://www.uniprot.org/uniprotkb/Q32LN3", "locus": { "chromosome": "6", "start_pos": 70988566, "end_pos": 71024317, "strand": "+", "evidence": [ { "database": "Ensembl Gene", "id": "ENSBTAG00000001772", "url": "https://www.ensembl.org/id/ENSBTAG00000001772" } ] } } ], "crossref": [ { "id": "Q32LN3", "url": "https://alphafold.ebi.ac.uk/entry/Q32LN3", "database": "AlphaFoldDB", "categories": [] }, { "id": "ENSBTAG00000001772", "url": "https://bgee.org/?page=gene&gene_id=ENSBTAG00000001772", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "cd02988", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd02988", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "531753", "url": "https://www.ncbi.nlm.nih.gov/gene/531753", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR024253", "url": "https://www.ebi.ac.uk/interpro/entry/IPR024253", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR036249", "url": "https://www.ebi.ac.uk/interpro/entry/IPR036249", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR051498", "url": "https://www.ebi.ac.uk/interpro/entry/IPR051498", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "bta:531753", "url": "https://www.genome.jp/dbget-bin/www_bget?bta:531753", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "DSCIQHY", "url": "https://omabrowser.org/oma/group/DSCIQHY/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "A0A3Q1NLI8", "url": "https://www.orthodb.org/?gene=A0A3Q1NLI8", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "Q32LN3", "url": "https://www.orthodb.org/?gene=Q32LN3", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR45809", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR45809", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR45809:SF1", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR45809:SF1", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF02114", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF02114", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "NP_001035641", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001035641", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A3Q1NLI8", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1NLI8", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A3Q1NLI8-1", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1NLI8-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "Q32LN3", "url": "https://www.uniprot.org/uniprotkb/Q32LN3", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "Q32LN3-1", "url": "https://www.uniprot.org/uniprotkb/Q32LN3-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MQDPNEDTEWNEILRDFGILPPKEEPKDEIEEMVLRLQKEAMVKPYEKMTLAELKEAEDEFDDEDMKAIEIYREKRLQEWKALKKKQKFGELREISGNQYVNEVTNAEKDVWVIIHLYRSSIPLCLLVNQHLSLLARKFPETKFVKAIANSCIEHYHDNCLPTIFVYKNGQIEGKFIGIIECGGINLKLEELEWKLAEVGAIQTDLEENPKKAIVDVMVSSIRNTSIYGDSDSSNSDSEDTK", "length": 242, "header": "sp|Q32LN3-1|PDCL2_BOVIN Isoform 1 of Phosducin-like protein 2 OS=Bos taurus OX=9913 GN=PDCL2 PE=2 SV=1 CANONICAL=Q32LN3-1" }, "isoforms": [ { "isoform_ac": "A0A3Q1NLI8-1", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1NLI8/entry", "sequence": { "sequence": "MQTDPNEDTEWNEILRDFGILPPKEEPKDEIEEMVLRLQKEAMVKPYEKMTLAELKEAEDEFDDEDMKAIEIYREKRLQEWKALKKKQKFGELREISGNQYVNEVTNAEKDVWVIIHLYRSSIPLCLLVNQHLSLLARKFPETKFVKAIANSCIEHYHDNCLPTIFVYKNGQIEGKFIGIIECGGINLKLEELEWKLAEVGAIQTDLEENPKKAIVDVMVSSIRNTSIYGDSDSSNSDSEDTK", "length": 243, "header": "tr|A0A3Q1NLI8-1|PDCL2_BOVIN Computationally mapped isoform of Phosducin-like protein 2 OS=Bos taurus OX=9913 GN=PDCL2 PE=2 SV=1 CANONICAL=Q32LN3-1" }, "locus": { "chromosome": "6", "start_pos": 71013306, "end_pos": 70988871, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000084575.2", "url": "https://www.ensembl.org/id/ENSBTAT00000084575.2" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000073283.1", "url": "https://www.ensembl.org/id/ENSBTAP00000073283.1" } ] } }, { "isoform_ac": "Q32LN3-1", "url": "https://www.uniprot.org/uniprotkb/Q32LN3/entry#Q32LN3-1", "sequence": { "sequence": "MQDPNEDTEWNEILRDFGILPPKEEPKDEIEEMVLRLQKEAMVKPYEKMTLAELKEAEDEFDDEDMKAIEIYREKRLQEWKALKKKQKFGELREISGNQYVNEVTNAEKDVWVIIHLYRSSIPLCLLVNQHLSLLARKFPETKFVKAIANSCIEHYHDNCLPTIFVYKNGQIEGKFIGIIECGGINLKLEELEWKLAEVGAIQTDLEENPKKAIVDVMVSSIRNTSIYGDSDSSNSDSEDTK", "length": 242, "header": "sp|Q32LN3-1|PDCL2_BOVIN Isoform 1 of Phosducin-like protein 2 OS=Bos taurus OX=9913 GN=PDCL2 PE=2 SV=1 CANONICAL=Q32LN3-1" }, "locus": { "chromosome": "6", "start_pos": 71024181, "end_pos": 70988871, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000055488.2", "url": "https://www.ensembl.org/id/ENSBTAT00000055488.2" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000050551.1", "url": "https://www.ensembl.org/id/ENSBTAP00000050551.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [ { "id": "bta:531753", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?bta:531753", "resource": "KEGG Pathway" } ], "orthologs": [ { "uniprot_canonical_ac": "A0A8I6B5E6-1", "protein_name": "Phosducin-like 2", "gene_name": "Pdcl2", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MQDPNEDTEWNEILRNFGILPPKEEPKDEIEEMVLRLQEEAMVKPYEKMTLAQLKEAEDEFDEEDIKAIEIYREKRLQEWKALTKKQKFGELREISGNQYVNEVTNAEKDLWVIIHLYRSSVPMCLVVNQHLSVLARKFPETKFVKAIVNSCIEHYHDNCLPTIFVYKNGQIEGKFIGVIECGGINLKLEELEWKLSQVGAIQTDLEENPKKGIADMMVSSIRNVSIYDSDSSGSDAEAK", "length": 240 }, "evidence": [ { "id": "Q32LN3", "url": "https://omabrowser.org/oma/group/Q32LN3/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "A0A8V0YJU0-1", "protein_name": "Phosducin like 2", "gene_name": "PDCL2", "tax_id": 9031, "organism": "Gallus gallus", "sequence": { "sequence": "MQDPNEDTEWNDVLRKFGILPPKEEPKDEIEEMVLRLQKEAEVKPYERMSLEELKEAEDDFDEADRKAIEMYRQQRLQEWKCLQRRQKYGELREISGEQYVKEVTNAPEDVWVIIHLYRSSIPMCLLVNEHLSHLAKKFPEAKFVKAAVNSCIQRYHDRCLPTILVYKSGEIKARFIGVAECGGAYLKVEELEWKLAEVGAIESDLEENPKKDIINMMTLSMQNISVHENMDTKSSDVLKPRIT", "length": 244 }, "evidence": [ { "id": "Q32LN3", "url": "https://omabrowser.org/oma/group/Q32LN3/", "database": "OMA" } ], "glygen_name": "Chicken", "common_name": "Chicken" }, { "uniprot_canonical_ac": "Q78Y63-1", "protein_name": "Phosducin-like protein 2", "gene_name": "Pdcl2", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MQDPNEDTEWNEILRNFGILPPKEEPKDEIEEMVLRLQQEAMVKPYEKMTLAQLKEAEDEFDEEDIKAIEIYREKRLQEWKALKKKQKFGELREISGNQYVNEVTNAEKDLWVVIHLYRSSVPMCLVVNQHLSVLARKFPETKFVKAIVNSCIEHYHDNCLPTIFVYKNGQIEGKFIGIIECGGINLKLEELEWKLSEVGAIQSDLEENPKKGIADMMVSSIRNISIYDSDSSGSDTEAK", "length": 240 }, "evidence": [ { "id": "Q32LN3", "url": "https://omabrowser.org/oma/group/Q32LN3/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q8N4E4-1", "protein_name": "Phosducin-like protein 2", "gene_name": "PDCL2", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MQDPNEDTEWNDILRDFGILPPKEESKDEIEEMVLRLQKEAMVKPFEKMTLAQLKEAEDEFDEEDMQAVETYRKKRLQEWKALKKKQKFGELREISGNQYVNEVTNAEEDVWVIIHLYRSSIPMCLLVNQHLSLLARKFPETKFVKAIVNSCIQHYHDNCLPTIFVYKNGQIEAKFIGIIECGGINLKLEELEWKLAEVGAIQTDLEENPRKDMVDMMVSSIRNTSIHDDSDSSNSDNDTK", "length": 241 }, "evidence": [ { "id": "Q32LN3", "url": "https://omabrowser.org/oma/group/Q32LN3/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" } ], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 2, "go_terms": [ { "name": "cytoplasm", "id": "GO:0005737", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005737", "evidence": [ { "database": "UniProtKB", "id": "Q32LN3", "url": "https://www.uniprot.org/uniprotkb/Q32LN3" } ], "pmid": "" }, { "name": "endoplasmic reticulum", "id": "GO:0005783", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005783", "evidence": [ { "database": "UniProtKB", "id": "Q32LN3", "url": "https://www.uniprot.org/uniprotkb/Q32LN3" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 3, "go_terms": [ { "name": "spermatid development", "id": "GO:0007286", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007286", "evidence": [ { "database": "UniProtKB", "id": "Q32LN3", "url": "https://www.uniprot.org/uniprotkb/Q32LN3" } ], "pmid": "" }, { "name": "protein folding", "id": "GO:0006457", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006457", "evidence": [ { "database": "UniProtKB", "id": "Q32LN3", "url": "https://www.uniprot.org/uniprotkb/Q32LN3" } ], "pmid": "" }, { "name": "acrosome assembly", "id": "GO:0001675", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0001675", "evidence": [ { "database": "UniProtKB", "id": "Q32LN3", "url": "https://www.uniprot.org/uniprotkb/Q32LN3" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 224, "end_pos": 226, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [ { "pdb_id": "AF-Q32LN3-F1", "pdb_chain": "global", "start_pos": 1, "end_pos": 242, "overlap": "1.0", "method": "AlphaFold", "type": "alphafold", "resolution": -1.0, "url": "https://data.glygen.org/ln2downloads/pdb/current/AF-Q32LN3-F1.pdb", "url_external": "https://alphafold.ebi.ac.uk/entry/Q32LN3" } ], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "Q32LN3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q32LN3" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "Phosducin", "eco_id": "ECO_0000255", "start_pos": 34, "end_pos": 201, "start_aa": "Val", "end_aa": "Ala", "glycosite_overlap": [] } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" }, { "name": "homologset.oma", "label": "OMA Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 224, "end_pos": 226 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": 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"NP_001014896", "name": "haloacid dehalogenase-like hydrolase domain-containing protein 3", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001014896" }, "gene_names": [ { "name": "HDHD3", "type": "recommended", "evidence": [ { "id": "Q5E9D6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q5E9D6" } ] }, { "name": "HDHD3", "type": "synonym", "evidence": [ { "id": "NP_001014896", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001014896" } ] } ], "protein_names": [ { "name": "Haloacid dehalogenase-like hydrolase domain-containing protein 3", "type": "recommended", "evidence": [ { "id": "Q5E9D6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q5E9D6/entry#names_and_taxonomy" } ] }, { "name": "haloacid dehalogenase-like hydrolase domain-containing protein 3", "type": "synonym", "evidence": [ { "id": "NP_001014896", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001014896" } ] } ], "function": [], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Bos taurus", "taxid": 9913, "evidence": [ { "database": "UniProtKB", "id": "Q5E9D6", "url": "https://www.uniprot.org/uniprotkb/Q5E9D6" } ], "common_name": "Bovine", "glygen_name": "Bovine", "reference_species": "Bos taurus [9913]" } ], "gene": [ { "name": "HDHD3", "url": "https://www.uniprot.org/uniprotkb/Q5E9D6", "locus": { "chromosome": "8", "start_pos": 102631185, "end_pos": 102634313, "strand": "+", "evidence": [ { "database": "Ensembl Gene", "id": "ENSBTAG00000000250", "url": "https://www.ensembl.org/id/ENSBTAG00000000250" } ] } } ], "crossref": [ { "id": "Q5E9D6", "url": "https://alphafold.ebi.ac.uk/entry/Q5E9D6", "database": "AlphaFoldDB", "categories": [] }, { "id": "ENSBTAG00000000250", "url": "https://bgee.org/?page=gene&gene_id=ENSBTAG00000000250", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "cd16415", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd16415", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "510680", "url": "https://www.ncbi.nlm.nih.gov/gene/510680", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR006439", "url": "https://www.ebi.ac.uk/interpro/entry/IPR006439", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR011949", "url": "https://www.ebi.ac.uk/interpro/entry/IPR011949", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR023214", "url": "https://www.ebi.ac.uk/interpro/entry/IPR023214", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR036412", "url": "https://www.ebi.ac.uk/interpro/entry/IPR036412", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR044924", "url": "https://www.ebi.ac.uk/interpro/entry/IPR044924", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR051828", "url": "https://www.ebi.ac.uk/interpro/entry/IPR051828", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "bta:510680", "url": "https://www.genome.jp/dbget-bin/www_bget?bta:510680", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "KCVGIIS", "url": "https://omabrowser.org/oma/group/KCVGIIS/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "A0A452DHL8", "url": "https://www.orthodb.org/?gene=A0A452DHL8", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "Q5E9D6", "url": "https://www.orthodb.org/?gene=Q5E9D6", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR46191", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR46191", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR46191:SF2", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR46191:SF2", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00702", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00702", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "NP_001014896", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001014896", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A452DHL8", "url": "https://www.uniprot.org/uniprotkb/A0A452DHL8", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A452DHL8-1", "url": "https://www.uniprot.org/uniprotkb/A0A452DHL8-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "Q5E9D6", "url": "https://www.uniprot.org/uniprotkb/Q5E9D6", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "Q5E9D6-1", "url": "https://www.uniprot.org/uniprotkb/Q5E9D6-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MAHRLQLRLLTWDVKDTLLRLRHPVGVEYATKARAHGLEVEATALGQAFKQAYKAQSQSFPNYGLGHGLTSHQWWLDLVQQTFHQAGVRDAQAVAPIAEQLYKDFSSPSTWQVLEGAEATLRGCRKRGLKLAVVSNFDRRLEDILEGVGLREHFDFVLTSEAAGWPKPDPRIFHEALHLAQVEPAVGAHIGDSYQRDYKGARAVGMHSFLVAGPEPLDPAVKDSVPQEHFLPSLSHLLPALDYLEGSSARL", "length": 251, "header": "sp|Q5E9D6-1|HDHD3_BOVIN Isoform 1 of Haloacid dehalogenase-like hydrolase domain-containing protein 3 OS=Bos taurus OX=9913 GN=HDHD3 PE=2 SV=1 CANONICAL=Q5E9D6-1" }, "isoforms": [ { "isoform_ac": "A0A452DHL8-1", "url": "https://www.uniprot.org/uniprotkb/A0A452DHL8/entry", "sequence": { "sequence": "MAHRLQLRLLTWDVKDTLLRLRHPVGVEYATKARAHGLEVEATALGQAFKQAYKAQSQSFPNYGLGHGLTSHQWWLDLVQQTFHQAGVRDAQAVAPIAEQLYKDFSSPSTWQVLEGAEATLRGCRKRGLKLAVVSNFDRRLEDILEGVGLREHFDFVLTSEAAGWPKPDPRIFHEALHLAQVEPAVGAHIGDSYQRDYKGARAVGMHSFLVAGPEPLDPAVKDPVPQEHFLPSLSHLLPALDYLEGSSARL", "length": 251, "header": "tr|A0A452DHL8-1|HDHD3_BOVIN Computationally mapped isoform of Haloacid dehalogenase-like hydrolase domain-containing protein 3 OS=Bos taurus OX=9913 GN=HDHD3 PE=2 SV=1 CANONICAL=Q5E9D6-1" }, "locus": { "chromosome": "8", "start_pos": 102632486, "end_pos": 102631733, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000000314.4", "url": "https://www.ensembl.org/id/ENSBTAT00000000314.4" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000000314.4", "url": "https://www.ensembl.org/id/ENSBTAP00000000314.4" } ] } }, { "isoform_ac": "Q5E9D6-1", "url": "https://www.uniprot.org/uniprotkb/Q5E9D6/entry#Q5E9D6-1", "sequence": { "sequence": "MAHRLQLRLLTWDVKDTLLRLRHPVGVEYATKARAHGLEVEATALGQAFKQAYKAQSQSFPNYGLGHGLTSHQWWLDLVQQTFHQAGVRDAQAVAPIAEQLYKDFSSPSTWQVLEGAEATLRGCRKRGLKLAVVSNFDRRLEDILEGVGLREHFDFVLTSEAAGWPKPDPRIFHEALHLAQVEPAVGAHIGDSYQRDYKGARAVGMHSFLVAGPEPLDPAVKDSVPQEHFLPSLSHLLPALDYLEGSSARL", "length": 251, "header": "sp|Q5E9D6-1|HDHD3_BOVIN Isoform 1 of Haloacid dehalogenase-like hydrolase domain-containing protein 3 OS=Bos taurus OX=9913 GN=HDHD3 PE=2 SV=1 CANONICAL=Q5E9D6-1" }, "locus": {} } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [ { "title": "Characterization of 954 bovine full-CDS cDNA sequences.", "journal": "BMC Genomics", "date": "2005", "authors": "Harhay Gregory P, Sonstegard Tad S, Keele John W, Heaton Michael P, Clawson Michael L, Snelling Warren M, Wiedmann Ralph T, Van Tassell Curt P, Smith Timothy P L", "evidence": [ { "database": "UniProtKB", "id": "Q5E9D6", "url": "https://www.uniprot.org/uniprotkb/Q5E9D6" } ], "reference": [ { "type": "PubMed", "id": "16305752", "url": "https://glygen.org/publication/PubMed/16305752" } ] } ], "pathway": [ { "id": "bta:510680", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?bta:510680", "resource": "KEGG Pathway" } ], "orthologs": [ { "uniprot_canonical_ac": "A0A287A5Y1-1", "protein_name": "Haloacid dehalogenase-like hydrolase domain-containing protein 3", "gene_name": "HDHD3", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MVHRLPLRLLTWDVKDTLLRLRHPVGVEYASKALAHGLQVEAAALGQAFPQVYKAQSHSFPNYGLSQGLTSRQWWLDVILQTFHQAGVGDAQVVIPIADQLYEDFSHPHTWQVLEGAKATLKGCQKRGLRLAVVSNFDRRLENILVGLGLRDYFDFVLTSEAAGWPKPDPRIFHEALRLAQVEPAATAHIGDSYRCDYKGARAVGMHSFLVAGPEPLDPAVKDSVPQEHILPSLSHLLPALDRLEGSPLGF", "length": 251 }, "evidence": [ { "id": "Q5E9D6", "url": "https://omabrowser.org/oma/group/Q5E9D6/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "G3HI00-1", "protein_name": "Haloacid dehalogenase-like hydrolase domain-containing protein 3", "gene_name": "Hdhd3", "tax_id": 10029, "organism": "Cricetulus griseus", "sequence": { "sequence": "MAHRLQMRLLTWDMKDTLIKLCRPVGEEYASKARAHGLVVEATALEQAFGQAYRVHSHNFPNYGQSCGLTSRQWWVDLILNTFHLAGVPDAQAIIPIADQLYNDYSSPSTWQVLEGAETTLKGCRKRGLRLAVISNFDRRLEDILVGLGLREHFDFVLTSEAAGCPKPDPRIFHKALQLACVEPAVAAHVGDSYPCDYQGARAVGMHSFLVVGSEPLDSSVRDSVPKEHILPSLSHLLPALDLLEASSPVS", "length": 251 }, "evidence": [ { "id": "Q5E9D6", "url": "https://omabrowser.org/oma/group/Q5E9D6/", "database": "OMA" } ], "glygen_name": "Hamster", "common_name": "Chinese hamster" }, { "uniprot_canonical_ac": "Q9BSH5-1", "protein_name": "Haloacid dehalogenase-like hydrolase domain-containing protein 3", "gene_name": "HDHD3", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MAHRLQIRLLTWDVKDTLLRLRHPLGEAYATKARAHGLEVEPSALEQGFRQAYRAQSHSFPNYGLSHGLTSRQWWLDVVLQTFHLAGVQDAQAVAPIAEQLYKDFSHPCTWQVLDGAEDTLRECRTRGLRLAVISNFDRRLEGILGGLGLREHFDFVLTSEAAGWPKPDPRIFQEALRLAHMEPVVAAHVGDNYLCDYQGPRAVGMHSFLVVGPQALDPVVRDSVPKEHILPSLAHLLPALDCLEGSTPGL", "length": 251 }, "evidence": [ { "id": "Q5E9D6", "url": "https://omabrowser.org/oma/group/Q5E9D6/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "Q9CYW4-1", "protein_name": "Haloacid dehalogenase-like hydrolase domain-containing protein 3", "gene_name": "Hdhd3", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MAHRLQMRLLTWDVKDTLIKLRRPVGEEYASKARAHGVVVEDITVEQAFRQAYRAQSHNFPNYGLSRGLTSRQWWKDVVLHTFRLAGVPDAQAMTPVADQLYEDFSSPFTWQVLEGAEMTLKGCRKRGLKLAVVSNFDRRLEDILTGLGLREHFDFVLTSEAVGCPKPDPRIFREALQRACVEPAVAAHVGDSYLCDYQGSQAVGMHSFLVAGSEPLDSAVRDSVPKEHILPSLSHLLPALDLLEASSPMS", "length": 251 }, "evidence": [ { "id": "Q5E9D6", "url": "https://omabrowser.org/oma/group/Q5E9D6/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q9M9T1-1", "protein_name": "Haloacid dehalogenase-like hydrolase (HAD) superfamily protein", "gene_name": "", "tax_id": 3702, "organism": "Arabidopsis thaliana", "sequence": { "sequence": "MEACLRCSRGSYLIEAMRPLSSSLRPSSSVSFSTGKPIKRAYDGLLLDAGGTLLQLSKPVHETYASLGQKYGLKTTPAEIKEGFKRVFSAPWPEKLRYQGDGRPFWKLVVSEATGCSDNDYFEDVYQYYANGEAWHLPEGAYETMSLLKDAGVKMAVVSNFDTRLRKLLKDLNVIDMFDAVIVSAEVGYEKPDERIFKSALEQISVDVNRAVHVGDDEGADKGGANAIGIACWLWGEDVQTFSDIQKRILVSEL", "length": 254 }, "evidence": [ { "id": "Q5E9D6", "url": "https://omabrowser.org/oma/group/Q5E9D6/", "database": "OMA" } ], "glygen_name": "Arabidopsis", "common_name": "Mouse-ear cress" }, { "uniprot_canonical_ac": "Q9W4J7-1", "protein_name": "Uncharacterized protein", "gene_name": "24639695", "tax_id": 7227, "organism": "Drosophila melanogaster", "sequence": { "sequence": "MSLTSQFVANLKRFRLVTFDVTDTLLRLEDPLRQYHQTAEEFGVTGVDRRRLEQCFRQQFKAMSSEHPNFGRYSPGLDWQRWWLQLVARTFSCVDHGLAPEKLEKIGQRLISVFRTSACWSHVNGAQELVQNVRNAGKCVGIISNFDSSLPQVLDAMGFAGKFDFILTSYEAGVMKPERGIFEIPLQRLQIPAEQALHIGNKLDMDYEGARNCGWSGLLVSNADNPHSFASLSSLLEALKTQPIRW", "length": 246 }, "evidence": [ { "id": "Q5E9D6", "url": "https://omabrowser.org/oma/group/Q5E9D6/", "database": "OMA" } ], "glygen_name": "Fruit fly", "common_name": "Fruit fly" } ], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 2, "go_terms": [ { "name": "nucleus", "id": "GO:0005634", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005634", "evidence": [ { "database": "UniProtKB", "id": "Q5E9D6", "url": "https://www.uniprot.org/uniprotkb/Q5E9D6" } ], "pmid": "" }, { "name": "nucleolus", "id": "GO:0005730", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005730", "evidence": [ { "database": "UniProtKB", "id": "Q5E9D6", "url": "https://www.uniprot.org/uniprotkb/Q5E9D6" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [ { "pdb_id": "AF-Q5E9D6-F1", "pdb_chain": "global", "start_pos": 1, "end_pos": 251, "overlap": "1.0", "method": "AlphaFold", "type": "alphafold", "resolution": -1.0, "url": "https://data.glygen.org/ln2downloads/pdb/current/AF-Q5E9D6-F1.pdb", "url_external": "https://alphafold.ebi.ac.uk/entry/Q5E9D6" } ], "lectin_list": [], "domain_list": [], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" }, { "name": 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"o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": 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"total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ], "tool_support": { "graph_view": "yes" } }, { "uniprot_canonical_ac": "Q0IIE6-1", "uniprot_ac": "Q0IIE6", "uniprot_id": "ELMD1_BOVIN", "mass": { "chemical_mass": 38036.0, "monoisotopic_mass": 38036.0 }, "refseq": { "ac": "NP_001071576", "name": "ELMO domain-containing protein 1", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001071576" }, "gene_names": [ { "name": "ELMOD1", "type": "recommended", "evidence": [ { "id": "Q0IIE6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q0IIE6" } ] }, { "name": "ELMOD1", "type": "synonym", "evidence": [ { "id": "NP_001071576", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001071576" } ] } ], "protein_names": [ { "name": "ELMO domain-containing protein 1", "type": "recommended", "evidence": [ { "id": "Q0IIE6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q0IIE6/entry#names_and_taxonomy" } ] }, { "name": "ELMO domain-containing protein 1", "type": "synonym", "evidence": [ { "id": "NP_001071576", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001071576" } ] }, { "name": "ELMO/CED-12 domain containing 1", "type": "synonym", "evidence": [ { "id": "NP_001071576", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001071576" } ] } ], "function": [ { "annotation": "Acts as a GTPase-activating protein (GAP) toward guanine nucleotide exchange factors like ARL2, ARL3, ARF1 and ARF6, but not for GTPases outside the Arf family.", "evidence": [ { "database": "UniProtKB", "id": "Q0IIE6", "url": "https://www.uniprot.org/uniprotkb/Q0IIE6#function" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Bos taurus", "taxid": 9913, "evidence": [ { "database": "UniProtKB", "id": "Q0IIE6", "url": "https://www.uniprot.org/uniprotkb/Q0IIE6" } ], "common_name": "Bovine", "glygen_name": "Bovine", "reference_species": "Bos taurus [9913]" } ], "gene": [ { "name": "ELMOD1", "url": "https://www.uniprot.org/uniprotkb/Q0IIE6", "locus": { "chromosome": "15", "start_pos": 17196895, "end_pos": 17111406, "strand": "-", "evidence": [ { "database": "Ensembl Gene", "id": "ENSBTAG00000002691", "url": "https://www.ensembl.org/id/ENSBTAG00000002691" } ] } } ], "crossref": [ { "id": "Q0IIE6", "url": "https://alphafold.ebi.ac.uk/entry/Q0IIE6", "database": "AlphaFoldDB", "categories": [] }, { "id": "ENSBTAG00000002691", "url": "https://bgee.org/?page=gene&gene_id=ENSBTAG00000002691", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "768233", "url": "https://www.ncbi.nlm.nih.gov/gene/768233", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR006816", "url": "https://www.ebi.ac.uk/interpro/entry/IPR006816", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR050868", "url": "https://www.ebi.ac.uk/interpro/entry/IPR050868", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "bta:768233", "url": "https://www.genome.jp/dbget-bin/www_bget?bta:768233", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "PHFQQTF", "url": "https://omabrowser.org/oma/group/PHFQQTF/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "A0A452DI07", "url": "https://www.orthodb.org/?gene=A0A452DI07", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "Q0IIE6", "url": "https://www.orthodb.org/?gene=Q0IIE6", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR12771", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR12771", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR12771:SF18", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR12771:SF18", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF04727", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF04727", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "NP_001071576", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001071576", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A452DI07", "url": "https://www.uniprot.org/uniprotkb/A0A452DI07", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A452DI07-1", "url": "https://www.uniprot.org/uniprotkb/A0A452DI07-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0AAA9T1Q2", "url": "https://www.uniprot.org/uniprotkb/A0AAA9T1Q2", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0AAA9T1Q2-1", "url": "https://www.uniprot.org/uniprotkb/A0AAA9T1Q2-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0AAA9U0M5", "url": "https://www.uniprot.org/uniprotkb/A0AAA9U0M5", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0AAA9U0M5-1", "url": "https://www.uniprot.org/uniprotkb/A0AAA9U0M5-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "Q0IIE6", "url": "https://www.uniprot.org/uniprotkb/Q0IIE6", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "Q0IIE6-1", "url": "https://www.uniprot.org/uniprotkb/Q0IIE6-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MKHFLRMLIQVCLFFYCKFLWRCLKFVMRKLTGRCELQRICYNTKPGASRTMKIETSLRDSKSKLLQTSVSVHPDAIEKTIDDIMELKKINPDINPQLGISLQACLLQIVGYRNLIADVEKLRRESYDSDNPQHEEMLLKLWKFLKPNTPLESRISKQWCEIGFQGDDPKTDFRGMGLLGLYNLQYFAERDAAAAQQVLSDSLHPKCSKFSKAEWEKKRMDKAIGYSFAIVGINITDLAYNLLVSGALKTHFYNIAPEAPTLSHFQQTFCYLMHEFHKFWIEEDPMDIMEFNRVREKFRKRIIKQLQNPDMALCPHFAASEGLINM", "length": 326, "header": "sp|Q0IIE6-1|ELMD1_BOVIN Isoform 1 of ELMO domain-containing protein 1 OS=Bos taurus OX=9913 GN=ELMOD1 PE=2 SV=1 CANONICAL=Q0IIE6-1" }, "isoforms": [ { "isoform_ac": "A0A452DI07-1", "url": "https://www.uniprot.org/uniprotkb/A0A452DI07/entry", "sequence": { "sequence": "MKHFLRMLIQVCLFFYCKFLWRCLKFVMRKLTGRCELQRICYNTKPGASRTMKIETSLRDSKSKLLQTSVSVHPDAIEKTIDDIMELKKINPDINPQLGISLQACLLQIVGYRNLIADVEKLRRESYDSDNPQHEEMLLKLWKFLKPNTPLESRISKQWCEIGFQGDDPKTDFRGMGLLGLYNLQYFAERDAAAAQQVLSDSLHPKCSKFSKAEWEKKRMDKAIGYSFAIVGINITDLAYNLLVSGALKTHFYNIAPEAPTLSHFQQTFCQTLTGLEEHRKIICQIIKLSDARVS", "length": 295, "header": "tr|A0A452DI07-1|ELMD1_BOVIN Computationally mapped isoform of ELMO domain-containing protein 1 OS=Bos taurus OX=9913 GN=ELMOD1 PE=2 SV=2 CANONICAL=Q0IIE6-1" }, "locus": { "chromosome": "15", "start_pos": 17195730, "end_pos": 17136675, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000003485.8", "url": "https://www.ensembl.org/id/ENSBTAT00000003485.8" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000003485.7", "url": "https://www.ensembl.org/id/ENSBTAP00000003485.7" } ] } }, { "isoform_ac": "A0AAA9T1Q2-1", "url": "https://www.uniprot.org/uniprotkb/A0AAA9T1Q2/entry", "sequence": { "sequence": "MKHFLRMLIQVCLFFYCKFLWRCLKFVMRKLTGRCELQRICYNTKPGASRTMKIETSLRDSKSKLLQTSVSVHPDAIEKTIDDIMELKKINPDINPQLGISLQACLLQIVGYRNLIADVEKLRRESYDSDNPQHEEMLLKLWKFLKPNTPLESRISKQWCEIGFQGDDPKTDFRGMGLLGLYNLQYFAERDAAAAQQVLSDSLHPKCRYSFAIVGINITDLAYNLLVSGALKTHFYNIAPEAPTLSHFQQTFCYLMHEFHKFWIEEDPMDIMEFNRVREKFRKRIIKQLQNPDMALCPHFAASEGLINM", "length": 309, "header": "tr|A0AAA9T1Q2-1|ELMD1_BOVIN Computationally mapped isoform of ELMO domain-containing protein 1 OS=Bos taurus OX=9913 GN=ELMOD1 PE=2 SV=1 CANONICAL=Q0IIE6-1" }, "locus": { "chromosome": "15", "start_pos": 17195878, "end_pos": 17136675, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000103354.2", "url": "https://www.ensembl.org/id/ENSBTAT00000103354.2" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000089593.1", "url": "https://www.ensembl.org/id/ENSBTAP00000089593.1" } ] } }, { "isoform_ac": "A0AAA9U0M5-1", "url": "https://www.uniprot.org/uniprotkb/A0AAA9U0M5/entry", "sequence": { "sequence": "MKHFLRMLIQVCLFFYCKFLWRCLKFVMRKLTGRCELQRICYNTKPGASRTMKIETSLRDSKSKLLQTSVSVHPDAIEKTIDDIMELKKINPDINPQLGISLQACLLQIVGYRNLIADVEKLRRESYDSDNPQHEEMLLKLWKFLKPNTPLESRISKQWCEIGFQGDDPKTDFRGMGLLGLYNLQYFAERDAAAAQQVLSDSLHPKCRDITKEEISKFSKAEWEKKRMDKAIGYSFAIVGINITDLAYNLLVSGALKTHFYNIAPEAPTLSHFQQTFCYLMHEFHKFWIEEDPMDIMEFNRVREKFRKRIIKQLQNPDMALCPHFAASEGLINM", "length": 334, "header": "tr|A0AAA9U0M5-1|A0AAA9U0M5_BOVIN Computationally mapped isoform of ELMO domain containing 1 OS=Bos taurus OX=9913 GN=ELMOD1 PE=4 SV=1 CANONICAL=Q0IIE6-1" }, "locus": { "chromosome": "15", "start_pos": 17195878, "end_pos": 17136675, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000125652.2", "url": "https://www.ensembl.org/id/ENSBTAT00000125652.2" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000102635.1", "url": "https://www.ensembl.org/id/ENSBTAP00000102635.1" } ] } }, { "isoform_ac": "Q0IIE6-1", "url": "https://www.uniprot.org/uniprotkb/Q0IIE6/entry#Q0IIE6-1", "sequence": { "sequence": "MKHFLRMLIQVCLFFYCKFLWRCLKFVMRKLTGRCELQRICYNTKPGASRTMKIETSLRDSKSKLLQTSVSVHPDAIEKTIDDIMELKKINPDINPQLGISLQACLLQIVGYRNLIADVEKLRRESYDSDNPQHEEMLLKLWKFLKPNTPLESRISKQWCEIGFQGDDPKTDFRGMGLLGLYNLQYFAERDAAAAQQVLSDSLHPKCSKFSKAEWEKKRMDKAIGYSFAIVGINITDLAYNLLVSGALKTHFYNIAPEAPTLSHFQQTFCYLMHEFHKFWIEEDPMDIMEFNRVREKFRKRIIKQLQNPDMALCPHFAASEGLINM", "length": 326, "header": "sp|Q0IIE6-1|ELMD1_BOVIN Isoform 1 of ELMO domain-containing protein 1 OS=Bos taurus OX=9913 GN=ELMOD1 PE=2 SV=1 CANONICAL=Q0IIE6-1" }, "locus": { "chromosome": "15", "start_pos": 17195878, "end_pos": 17136675, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000070105.3", "url": "https://www.ensembl.org/id/ENSBTAT00000070105.3" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000059345.1", "url": "https://www.ensembl.org/id/ENSBTAP00000059345.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [ { "id": "bta:768233", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?bta:768233", "resource": "KEGG Pathway" } ], "orthologs": [ { "uniprot_canonical_ac": "A0A287A7Y9-1", "protein_name": "ELMO domain containing 1", "gene_name": "ELMOD1", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MKHFLRMLIQVCLYFYCKFLWRCLKFVMRKLTGRCELQRICYNTKPGASRTMKIETSLRDSKSKLLQTSVSVHPDAIEKTIEDIMELKKINPDINPQLGISLQACLLQIVGYRNLIADVEKLRREPYDSENPQHEEMLLQLWKFLKPNTPLESRISKQWCEIGFQGDDPKTDFRGMGLLGLYNLQYFAERDAAGAQQVLSDSLHPKCSKFSKAEWEKKRMDKAIGYSFAIVGINITDLAYNLLVSGALKTHFYNIAPEAPTLSHFQQTFCYLMHEFHKFWIEEDPMDIMEFNRVREKFRKRIIKQLQNPDMALCPHFAASEGLINM", "length": 326 }, "evidence": [ { "id": "Q0IIE6", "url": "https://omabrowser.org/oma/group/Q0IIE6/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "A0A8I6GJG9-1", "protein_name": "ELMO domain containing 1", "gene_name": "Elmod1", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MGDSQSLHLLVLRMPENLTAVNGEKRMSLKLSFCQLLTQLSIGRVLSFVPHRMLIQVCLYFYCKFLWRCMKFVMRKLTGRCELQRICYGTKPGASRTMKIETSLRDSKSKLLQTSVSVHPDAIEKTIDDIMELKKINPDINPQLGISLQACLLQIVGYRNLIADVEKLRREPYDSDNPQHEEMLLKLWEFLKPNTPLESRISKQWCEIGFQGDDPKTDFRGMGLLGLYNLQYFAERDATVAQQVLCDSVHPKCSKFSKTEWEKKKMDKAIGYSFAIVGINITDLAYNLLVSGALKTHFYNIAPEAPTLSHFQQTFCYLMHEFHKFWIEEDPMDIMEFNRVREKFRKRIIKQLQNPDMALCPHFAASEGLINM", "length": 372 }, "evidence": [ { "id": "Q0IIE6", "url": "https://omabrowser.org/oma/group/Q0IIE6/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "A0A8V0XPZ9-1", "protein_name": "ELMO domain containing 1", "gene_name": "ELMOD1", "tax_id": 9031, "organism": "Gallus gallus", "sequence": { "sequence": "MKHFLRMFIQVCLYFYCKCLWRCLKFVVRKLTGRCELQRICYNTKPGAARTMKIEASLKGSKSKRLQTSVSVHPDAIEKTIDDIMELKKINPDINPQLGVSLQACLLQIVGYRNLIVEVEKLRREPYDSENLQHEEMLLKLWKCLKPNSPLKARISKQWCEIGFQGDDPKTDFRGMGLLGLYNLVYFAEWDTEVAQQVLSDSLHPKYSQFSKVEWEKKKFDKAIGYSFAIVGINITDLAYNLLVSGALKTHFYNVAPEAPTLTHFQQTFCYLMHEFHKFWIEEDPLDIMEFNRVREKFHKRILKQLQNPEMALCPHFAASESLINM", "length": 326 }, "evidence": [ { "id": "Q0IIE6", "url": "https://omabrowser.org/oma/group/Q0IIE6/", "database": "OMA" } ], "glygen_name": "Chicken", "common_name": "Chicken" }, { "uniprot_canonical_ac": "E9QCF8-1", "protein_name": "ELMO domain-containing protein 1", "gene_name": "elmod1", "tax_id": 7955, "organism": "Danio rerio", "sequence": { "sequence": "MKHFLRVLTQFLVFLYCKCLWRGLKFVIRKVTGRCELQRICYNNKPGARRTLKIESSLRCSKHELLQSAISVHPDSVEKSIDDIMALKKINLDTNPQLGISLQACLLQIVGYRNLVVEVEKLRREPYDCENPAHEEMLMKLWKELRPDSPLSGRISKQWCEIGFQGNDPKTDFRGMGLLGLHNLLYFAEHDKATALQVLHDSLQPKHSKMSKAEWEKKKFDKAIGYSFAIVGINITDLAYSLLVSGALKTHLYNVAPEMPSLVHFQQTFCYLMQEFHRFWMEEDPCDIMEFNRVRTKFYKRVLKQLKNPDMALCPHFTASDLHLVNL", "length": 327 }, "evidence": [ { "id": "Q0IIE6", "url": "https://omabrowser.org/oma/group/Q0IIE6/", "database": "OMA" } ], "glygen_name": "Zebrafish", "common_name": "Zebrafish" }, { "uniprot_canonical_ac": "Q3V1U8-1", "protein_name": "ELMO domain-containing protein 1", "gene_name": "Elmod1", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MKHFLRMLIQVCLYFYCKFLWRCMKFVMRKLTGRCELQRICYGTKPGASRTMKIETSLRDSKSKLLQTSVSVHPDAIEKTIDDIMELKKINPDINPQLGISLQACLLQIVGYRNLIADVEKLRREPYDSDNPQHEEMLLKLWELLKPNTPLESRVSKQWCEIGFQGDDPKTDFRGMGLLGLYNLQYFAERDATVAQQVLSDSVHPKCSKFSKIEWEKKKMDKAIGYSFAIVGINITDLAYNLLVSGALKTHFYNIAPEAPTLSHFQQTFCYLMHEFHKFWIEEDPMDIMEFNRVREKFRKRIIKQLQNPDMALCPHFAASEGLINM", "length": 326 }, "evidence": [ { "id": "Q0IIE6", "url": "https://omabrowser.org/oma/group/Q0IIE6/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q8N336-1", "protein_name": "ELMO domain-containing protein 1", "gene_name": "ELMOD1", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MKHFLRMLIQVCLYFYCKFLWRCLKFVMRKLTGRCELQRICYNTKPGASRTMKIETSLRDSKSKLLQTSVSVHPDAIEKTIEDIMELKKINPDVNPQLGISLQACLLQIVGYRNLIADVEKLRREAYDSDNPQHEEMLLKLWKFLKPNTPLESRISKQWCEIGFQGDDPKTDFRGMGLLGLYNLQYFAERDATAAQQVLSDSLHPKCRDITKEEISKFSKAEWEKKRMDKAIGYSFAIVGINITDLAYNLLVSGALKTHFYNIAPEAPTLSHFQQTFCYLMHEFHKFWIEEDPMDIMEFNRVREKFRKRIIKQLQNPDMALCPHFAASEGLINM", "length": 334 }, "evidence": [ { "id": "Q0IIE6", "url": "https://omabrowser.org/oma/group/Q0IIE6/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" } ], "go_annotation": { "categories": [ { "name": "Molecular Function", "total": 1, "go_terms": [ { "name": "GTPase activator activity", "id": "GO:0005096", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005096", "evidence": [ { "database": "UniProtKB", "id": "Q0IIE6", "url": "https://www.uniprot.org/uniprotkb/Q0IIE6" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 3, "go_terms": [ { "name": "Golgi apparatus", "id": "GO:0005794", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005794", "evidence": [ { "database": "UniProtKB", "id": "Q0IIE6", "url": "https://www.uniprot.org/uniprotkb/Q0IIE6" } ], "pmid": "" }, { "name": "cilium", "id": "GO:0005929", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005929", "evidence": [ { "database": "UniProtKB", "id": "Q0IIE6", "url": "https://www.uniprot.org/uniprotkb/Q0IIE6" } ], "pmid": "" }, { "name": "synapse", "id": "GO:0045202", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0045202", "evidence": [ { "database": "UniProtKB", "id": "Q0IIE6", "url": "https://www.uniprot.org/uniprotkb/Q0IIE6" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 1, "go_terms": [ { "name": "cilium assembly", "id": "GO:0060271", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0060271", "evidence": [ { "database": "UniProtKB", "id": "Q0IIE6", "url": "https://www.uniprot.org/uniprotkb/Q0IIE6" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 234, "end_pos": 236, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [ { "pdb_id": "AF-Q0IIE6-F1", "pdb_chain": "global", "start_pos": 1, "end_pos": 326, "overlap": "1.0", "method": "AlphaFold", "type": "alphafold", "resolution": -1.0, "url": "https://data.glygen.org/ln2downloads/pdb/current/AF-Q0IIE6-F1.pdb", "url_external": "https://alphafold.ebi.ac.uk/entry/Q0IIE6" } ], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "Q0IIE6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q0IIE6" }, { "id": "PRU00664", "database": "PROSITE", "url": "https://prosite.expasy.org/PRU00664" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "ELMO", "eco_id": "ECO_0000255", "start_pos": 133, "end_pos": 306, "start_aa": "Gln", "end_aa": "Leu", "glycosite_overlap": [] } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": 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"Protein Classification" ] }, { "id": "PTHR18444:SF9", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR18444:SF9", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF10209", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF10209", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "NP_001032707", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001032707", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A452DIE0", "url": "https://www.uniprot.org/uniprotkb/A0A452DIE0", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A452DIE0-1", "url": "https://www.uniprot.org/uniprotkb/A0A452DIE0-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0AAA9SVQ9", "url": "https://www.uniprot.org/uniprotkb/A0AAA9SVQ9", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0AAA9SVQ9-1", "url": "https://www.uniprot.org/uniprotkb/A0AAA9SVQ9-1", "database": 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"url": "https://www.uniprot.org/uniprotkb/Q32KX9-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MASEDVTITVRLIRSFEHRNFRPVVYHGVHLDQTVKDFIVFLKQDIPLRASLPPPFRNYKYDKLKIVHQAHKSKTNELVLSLEDDDRLLLKEDSTLKAAGIASETEIAFFCEEDYKNYKANPISSW", "length": 126, "header": "sp|Q32KX9-1|CB076_BOVIN Isoform 1 of UPF0538 protein C2orf76 homolog OS=Bos taurus OX=9913 GN= PE=2 SV=1 CANONICAL=Q32KX9-1" }, "isoforms": [ { "isoform_ac": "A0A452DIE0-1", "url": "https://www.uniprot.org/uniprotkb/A0A452DIE0/entry", "sequence": { "sequence": "MYDGGVPNRPKLPPSCQTLCQPRLNPRGFPCASAARRSRRGRREQEFLHMASEDVTITVRLIRSFEHRNFRPVVYHGVHLDQTVKDFIVFLKQDIPLRASLPPPFRNYKYDKLKIVHQAHKSKTNELVLSLEDDDRLLLKEDSTLKAAGIASETEIAFFCEEDYKNYKANPISSW", "length": 175, "header": "tr|A0A452DIE0-1|CB076_BOVIN Computationally mapped isoform of UPF0538 protein C2orf76 homolog OS=Bos taurus OX=9913 GN= PE=2 SV=1 CANONICAL=Q32KX9-1" }, "locus": { "chromosome": "2", "start_pos": 71192356, "end_pos": 71107983, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000014020.6", "url": "https://www.ensembl.org/id/ENSBTAT00000014020.6" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000014020.5", "url": "https://www.ensembl.org/id/ENSBTAP00000014020.5" } ] } }, { "isoform_ac": "A0AAA9SVQ9-1", "url": "https://www.uniprot.org/uniprotkb/A0AAA9SVQ9/entry", "sequence": { "sequence": "MASEDVTITVRLIRSFEHRNFRPVVYHGVHLDQTVKDFIVFLKQDIPLRASLPPPFRNYKYDKLKIVHQAHKSKTNELVLSLEDDDRLLLKEDSTLKAAGIDTCRRGGDALAYVGHPESWPGLSLLGNCCSLLRRRGEGKMRLSYFGHAGAVARGV", "length": 156, "header": "tr|A0AAA9SVQ9-1|CB076_BOVIN Computationally mapped isoform of UPF0538 protein C2orf76 homolog OS=Bos taurus OX=9913 GN= PE=2 SV=1 CANONICAL=Q32KX9-1" }, "locus": { "chromosome": "2", "start_pos": 71150074, "end_pos": 71101157, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000107247.1", "url": "https://www.ensembl.org/id/ENSBTAT00000107247.1" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000088099.1", "url": "https://www.ensembl.org/id/ENSBTAP00000088099.1" } ] } }, { "isoform_ac": "A0AAA9TEP4-1", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TEP4/entry", "sequence": { "sequence": "ASPPVLGPGETANQKLDVRWGRAQPPQAAPKLPNSLPTSLEPAGVSLRKRSEEESKGTPGADIPLRASLPPPFRNYKYDKLKIVHQAHKSKTNELVLSLEDDDRLLLKEDSTLKAAGIASETEIAFFCEEDYKNYKANPISSW", "length": 143, "header": "tr|A0AAA9TEP4-1|CB076_BOVIN Computationally mapped isoform of UPF0538 protein C2orf76 homolog OS=Bos taurus OX=9913 GN= PE=2 SV=1 CANONICAL=Q32KX9-1" }, "locus": { "chromosome": "2", "start_pos": 71192405, "end_pos": 71107983, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000122075.1", "url": "https://www.ensembl.org/id/ENSBTAT00000122075.1" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000097073.1", "url": "https://www.ensembl.org/id/ENSBTAP00000097073.1" } ] } }, { "isoform_ac": "A0AAA9TFZ4-1", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TFZ4/entry", "sequence": { "sequence": "MYDGGVPNRPKLPPSCQTLCQPRLNPRGFPCASAARRSRRGRREQFSLCTHVRDSQEYLHMNDVAGLKDIPLRASLPPPFRNYKYDKLKIVHQAHKSKTNELVLSLEDDDRLLLKEDSTLKAAGIASETEIAFFCEEDYKNYKANPISSW", "length": 150, "header": "tr|A0AAA9TFZ4-1|CB076_BOVIN Computationally mapped isoform of UPF0538 protein C2orf76 homolog OS=Bos taurus OX=9913 GN= PE=2 SV=1 CANONICAL=Q32KX9-1" }, "locus": { "chromosome": "2", "start_pos": 71192356, "end_pos": 71107983, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000122847.1", "url": "https://www.ensembl.org/id/ENSBTAT00000122847.1" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000095945.1", "url": "https://www.ensembl.org/id/ENSBTAP00000095945.1" } ] } }, { "isoform_ac": "A0AAA9TIH4-1", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TIH4/entry", "sequence": { "sequence": "MYDGGVPNRPKLPPSCQTLCQPRLNPRGFPCASAARRSRRGRREQEFLHMASEDVTITVRLIRSFEHRNFRPVVYHGVHLDQTVKDFIVFLKQDIPLRASLPPPFRNYKYDKLKIVHQAHKSKTNELVLSLEDDDRLLLKEDSTLKAAGIGNGSPLQCSCLENPRDGGAWWAAVYGVSQSWT", "length": 182, "header": "tr|A0AAA9TIH4-1|CB076_BOVIN Computationally mapped isoform of UPF0538 protein C2orf76 homolog OS=Bos taurus OX=9913 GN= PE=2 SV=1 CANONICAL=Q32KX9-1" }, "locus": { "chromosome": "2", "start_pos": 71192356, "end_pos": 71114653, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000100197.1", "url": "https://www.ensembl.org/id/ENSBTAT00000100197.1" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000096022.1", "url": "https://www.ensembl.org/id/ENSBTAP00000096022.1" } ] } }, { "isoform_ac": "Q32KX9-1", "url": "https://www.uniprot.org/uniprotkb/Q32KX9/entry#Q32KX9-1", "sequence": { "sequence": "MASEDVTITVRLIRSFEHRNFRPVVYHGVHLDQTVKDFIVFLKQDIPLRASLPPPFRNYKYDKLKIVHQAHKSKTNELVLSLEDDDRLLLKEDSTLKAAGIASETEIAFFCEEDYKNYKANPISSW", "length": 126, "header": "sp|Q32KX9-1|CB076_BOVIN Isoform 1 of UPF0538 protein C2orf76 homolog OS=Bos taurus OX=9913 GN= PE=2 SV=1 CANONICAL=Q32KX9-1" }, "locus": {} } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [ { "id": "bta:613457", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?bta:613457", "resource": "KEGG Pathway" } ], "orthologs": [ { "uniprot_canonical_ac": "A0A8V0ZFQ3-1", "protein_name": "C2orf76 homolog", "gene_name": "C2orf76", "tax_id": 9031, "organism": "Gallus gallus", "sequence": { "sequence": "MSAESSTITVRLVRSFEHRNFRPVVYHGVNLDQTVKQFIAFVQKDVPSRTGLPPPFKTYKYDTMKIIHQAHKSKTGDLVVSLEDDDNLILKEDSTLKAAGVANETELAFFCEEDYRSYKANPVSAW", "length": 126 }, "evidence": [ { "id": "Q32KX9", "url": "https://omabrowser.org/oma/group/Q32KX9/", "database": "OMA" } ], "glygen_name": "Chicken", "common_name": "Chicken" }, { "uniprot_canonical_ac": "A0A9J7JSR4-1", "protein_name": "UPF0538 protein C2orf76 homolog isoform X1", "gene_name": "C5H2orf76", "tax_id": 10029, "organism": "Cricetulus griseus", "sequence": { "sequence": "MCSEELNSVLTLGQYSLHMAAEEATVTVRLIRSFEHRNFKPVVYHRVNLDQTVKEFIIFLKQDVPLRTSLPPPLRNYKYDTLKILHQAHKAKTNELVLGLEDDDTLLLKEDRTLKDSGIASETEIAFFCEEDYKRYKANPTSSW", "length": 144 }, "evidence": [ { "id": "Q32KX9", "url": "https://omabrowser.org/oma/group/Q32KX9/", "database": "OMA" } ], "glygen_name": "Hamster", "common_name": "Chinese hamster" }, { "uniprot_canonical_ac": "A0ABK0M1X1-1", "protein_name": "Similar to chromosome 2 open reading frame 76", "gene_name": "C13h2orf76", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MAVEEATITVRLIRSFEHRNFKPVVYHRVNLHQTVKEFIIFLKQDVPSRTSLPPPLRNYKYDTLKILHQAHKAKTNELVLGLEDDDTLLLKEDRTLKDSGVGAVSASLDISAQKFPICQRQFCAL", "length": 125 }, "evidence": [ { "id": "Q32KX9", "url": "https://omabrowser.org/oma/group/Q32KX9/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "P36154-1", "protein_name": "Altered inheritance rate of mitochondria protein 29", "gene_name": "AIM29", "tax_id": 559292, "organism": "Saccharomyces cerevisiae S288C", "sequence": { "sequence": "MNSTKRLKMSTTFHDYDLEEPLTSNARPLKNSVITIRVIKSFPYRNVKNIVLHDYDLADKTAKDLFNDVLNKIQNEGSFRPFRNVKFDTLKIYTHAHGSKTVNLVINFDHDDDWTLDIENDKKKLFEYGIENETEISLFNKEDYLRFKENPEEKW", "length": 155 }, "evidence": [ { "id": "Q32KX9", "url": "https://omabrowser.org/oma/group/Q32KX9/", "database": "OMA" } ], "glygen_name": "Yeast", "common_name": "Baker's yeast" }, { "uniprot_canonical_ac": "Q3KRA6-1", "protein_name": "UPF0538 protein C2orf76", "gene_name": "C2orf76", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MAPGEVTITVRLIRSFEHRNFKPVVYHGVNLDQTVKEFIVFLKQDIPLRTNLPPPFRNYKYDALKIIHQAHKSKTNELVLSLEDDERLLLKEDSTLKAAGIASETEIAFFCEEDYKNYKANPISSW", "length": 126 }, "evidence": [ { "id": "Q32KX9", "url": "https://omabrowser.org/oma/group/Q32KX9/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "Q9CRW3-1", "protein_name": "UPF0538 protein C2orf76 homolog", "gene_name": "", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MAAEEATLTVRLIRSFEHRNFKPVVYHGVNLHQTVKEFIIFLKQDVPLRTSLPPPLRNYKYDTLKILHQAHKAKTNELVLGLEDDDTLLLKEDRTLKDSGVASETEIAFFCGEDYKRYKANPISSW", "length": 126 }, "evidence": [ { "id": "Q32KX9", "url": "https://omabrowser.org/oma/group/Q32KX9/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" } ], "go_annotation": {}, "pro_annotation": [], "site_annotation": [], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [ { "pdb_id": "AF-Q32KX9-F1", "pdb_chain": "global", "start_pos": 1, "end_pos": 126, "overlap": "1.0", "method": "AlphaFold", "type": "alphafold", "resolution": -1.0, "url": "https://data.glygen.org/ln2downloads/pdb/current/AF-Q32KX9-F1.pdb", "url_external": "https://alphafold.ebi.ac.uk/entry/Q32KX9" } ], "lectin_list": [], "domain_list": [], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" }, { "name": "homologset.oma", "label": "OMA Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ], "tool_support": { "graph_view": "yes" } }, { "uniprot_canonical_ac": "Q29S05-1", "uniprot_ac": "Q29S05", "uniprot_id": "N42L1_BOVIN", "mass": { "chemical_mass": 20472.0, "monoisotopic_mass": 20472.0 }, "refseq": { "ac": "NP_001040039", "name": "NEDD4-binding protein 2-like 1", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001040039" }, "gene_names": [ { "name": "N4BP2L1", "type": "recommended", "evidence": [ { "id": "Q29S05", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q29S05" } ] }, { "name": "N4BP2L1", "type": "synonym", "evidence": [ { "id": "NP_001040039", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001040039" } ] } ], "protein_names": [ { "name": "NEDD4-binding protein 2-like 1", "type": "recommended", "evidence": [ { "id": "Q29S05", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q29S05/entry#names_and_taxonomy" } ] }, { "name": "NEDD4-binding protein 2-like 1", "type": "synonym", "evidence": [ { "id": "NP_001040039", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001040039" } ] } ], "function": [ { "annotation": "Might play a role in adipocyte differentiation and triglyceride accumulation.", "evidence": [ { "database": "UniProtKB", "id": "Q29S05", "url": "https://www.uniprot.org/uniprotkb/Q29S05#function" }, { "database": "UniProtKB", "id": "Q3V2Q8", "url": "https://www.uniprot.org/uniprotkb/Q3V2Q8#function" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Bos taurus", "taxid": 9913, "evidence": [ { "database": "UniProtKB", "id": "Q29S05", "url": "https://www.uniprot.org/uniprotkb/Q29S05" } ], "common_name": "Bovine", "glygen_name": "Bovine", "reference_species": "Bos taurus [9913]" } ], "gene": [ { "name": "N4BP2L1", "url": "https://www.uniprot.org/uniprotkb/Q29S05", "locus": { "chromosome": "12", "start_pos": 28653915, "end_pos": 28591492, "strand": "-", "evidence": [ { "database": "Ensembl Gene", "id": "ENSBTAG00000000993", "url": "https://www.ensembl.org/id/ENSBTAG00000000993" } ] } } ], "crossref": [ { "id": "Q29S05", "url": "https://alphafold.ebi.ac.uk/entry/Q29S05", "database": "AlphaFoldDB", "categories": [] }, { "id": "ENSBTAG00000000993", "url": "https://bgee.org/?page=gene&gene_id=ENSBTAG00000000993", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "616069", "url": "https://www.ncbi.nlm.nih.gov/gene/616069", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR026302", "url": "https://www.ebi.ac.uk/interpro/entry/IPR026302", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR027417", "url": "https://www.ebi.ac.uk/interpro/entry/IPR027417", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "bta:616069", "url": "https://www.genome.jp/dbget-bin/www_bget?bta:616069", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "GYWNTYS", "url": "https://omabrowser.org/oma/group/GYWNTYS/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "A0A452DIE8", "url": "https://www.orthodb.org/?gene=A0A452DIE8", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "Q29S05", "url": "https://www.orthodb.org/?gene=Q29S05", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR13308", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR13308", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR13308:SF5", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR13308:SF5", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF13671", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF13671", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "NP_001040039", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001040039", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A452DIE8", "url": "https://www.uniprot.org/uniprotkb/A0A452DIE8", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A452DIE8-1", "url": "https://www.uniprot.org/uniprotkb/A0A452DIE8-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0AAA9S5Q7", "url": "https://www.uniprot.org/uniprotkb/A0AAA9S5Q7", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0AAA9S5Q7-1", "url": "https://www.uniprot.org/uniprotkb/A0AAA9S5Q7-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0AAF7ABZ7", "url": "https://www.uniprot.org/uniprotkb/A0AAF7ABZ7", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0AAF7ABZ7-1", "url": "https://www.uniprot.org/uniprotkb/A0AAF7ABZ7-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "Q29S05", "url": "https://www.uniprot.org/uniprotkb/Q29S05", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "Q29S05-1", "url": "https://www.uniprot.org/uniprotkb/Q29S05-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MEESFLESFGRLSLRQQQPPPPRPPAPPPLRGTPPRRHSFRKHLYLLRGLPGSGKTTLARQLQHDFPRALIFSTDDFFFREDGAYEFNPDFLEEAHEWNQKRARKAMRNGISPIIIDNTNLHAWEMKPYAVMVFQTEQKNLFRLEMDMVVFRPEMKKHSWSPKRENTPNERTV", "length": 173, "header": "sp|Q29S05-1|N42L1_BOVIN Isoform 1 of NEDD4-binding protein 2-like 1 OS=Bos taurus OX=9913 GN=N4BP2L1 PE=2 SV=1 CANONICAL=Q29S05-1" }, "isoforms": [ { "isoform_ac": "A0A452DIE8-1", "url": "https://www.uniprot.org/uniprotkb/A0A452DIE8/entry", "sequence": { "sequence": "MEESFLESFGRLSLRQQQPPPPRPPAPPPLRGTPPRRHSFRKHLYLLRGLPGSGKTTLARQLQHDFPRALIFSTDDFFFREDGAYEFNPDFLEEAHEWNQKRARKAMRNGISPIIIDNTNLHAWEMKPYAVMALENNYEVIFREPDTRWKFNVQELARRNIHGVPREKIHRMKERYEHDVTFYSVLHAEKPSRANRNQDRNNASPSNGAGYWNTYAEFPHRRAHGSFTNESSFNRRGGCHHGY", "length": 243, "header": "tr|A0A452DIE8-1|N42L1_BOVIN Computationally mapped isoform of NEDD4-binding protein 2-like 1 OS=Bos taurus OX=9913 GN=N4BP2L1 PE=2 SV=1 CANONICAL=Q29S05-1" }, "locus": { "chromosome": "12", "start_pos": 28612877, "end_pos": 28591691, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000001315.6", "url": "https://www.ensembl.org/id/ENSBTAT00000001315.6" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000001315.4", "url": "https://www.ensembl.org/id/ENSBTAP00000001315.4" } ] } }, { "isoform_ac": "A0AAA9S5Q7-1", "url": "https://www.uniprot.org/uniprotkb/A0AAA9S5Q7/entry", "sequence": { "sequence": "MEESFLESFGRLSLRQQQPPPPRPPAPPPLRGTPPRRHSFRKHLYLLRGLPGSGKTTLARQLQHDFPRALIFSTDDFFFREDGAYEFNPDFLEEAHEWNQKRARKAMRNGISPIIIDNTNLHAWEMKPYAVMVFQTEQKNLFRLEMDMVVFRPEMKKHSWSPKRENTPNERTE", "length": 173, "header": "tr|A0AAA9S5Q7-1|N42L1_BOVIN Computationally mapped isoform of NEDD4-binding protein 2-like 1 OS=Bos taurus OX=9913 GN=N4BP2L1 PE=2 SV=1 CANONICAL=Q29S05-1" }, "locus": { "chromosome": "12", "start_pos": 28652911, "end_pos": 28591691, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000095830.2", "url": "https://www.ensembl.org/id/ENSBTAT00000095830.2" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000077494.1", "url": "https://www.ensembl.org/id/ENSBTAP00000077494.1" } ] } }, { "isoform_ac": "A0AAF7ABZ7-1", "url": "https://www.uniprot.org/uniprotkb/A0AAF7ABZ7/entry", "sequence": { "sequence": "MEESFLESFGRLSLRQQQPPPPRPPAPPPLRGTPPRRHSFRKHLYLLRGLPGSGKTTLARQLQHDFPRALIFSTDDFFFREDGAYEFNPDFLEEAHEWNQKRARKAMRNGISPIIIDNTNLHAWEMKPYAVMVFQTEQKNLFRLEMDMVVFRPEMKKHSWSPKRENTPNERTGKN", "length": 175, "header": "tr|A0AAF7ABZ7-1|A0AAF7ABZ7_BOVIN Computationally mapped isoform of NEDD4 binding protein 2 like 1 OS=Bos taurus OX=9913 GN=N4BP2L1 PE=4 SV=1 CANONICAL=Q29S05-1" }, "locus": { "chromosome": "12", "start_pos": 28613127, "end_pos": 28591691, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000071120.3", "url": "https://www.ensembl.org/id/ENSBTAT00000071120.3" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000066598.2", "url": "https://www.ensembl.org/id/ENSBTAP00000066598.2" } ] } }, { "isoform_ac": "Q29S05-1", "url": "https://www.uniprot.org/uniprotkb/Q29S05/entry#Q29S05-1", "sequence": { "sequence": "MEESFLESFGRLSLRQQQPPPPRPPAPPPLRGTPPRRHSFRKHLYLLRGLPGSGKTTLARQLQHDFPRALIFSTDDFFFREDGAYEFNPDFLEEAHEWNQKRARKAMRNGISPIIIDNTNLHAWEMKPYAVMVFQTEQKNLFRLEMDMVVFRPEMKKHSWSPKRENTPNERTV", "length": 173, "header": "sp|Q29S05-1|N42L1_BOVIN Isoform 1 of NEDD4-binding protein 2-like 1 OS=Bos taurus OX=9913 GN=N4BP2L1 PE=2 SV=1 CANONICAL=Q29S05-1" }, "locus": { "chromosome": "12", "start_pos": 28612675, "end_pos": 28591691, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000142522.1", "url": "https://www.ensembl.org/id/ENSBTAT00000142522.1" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000106231.1", "url": "https://www.ensembl.org/id/ENSBTAP00000106231.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [ { "id": "bta:616069", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?bta:616069", "resource": "KEGG Pathway" } ], "orthologs": [ { "uniprot_canonical_ac": "A0A8V0XM15-1", "protein_name": "NEDD4 binding protein 2 like 1", "gene_name": "N4BP2L1", "tax_id": 9031, "organism": "Gallus gallus", "sequence": { "sequence": "MHGVVVTGRGRARPRQFPPPPSGPGPAQRAVPGRMEEQLLRALGGLSLQPPPRRSPRRFGKTLVLLRGLPGSGKSTLARQLKCDYPSAVVLSTDDFFSRNGVYVFDPDFLEDAHKWNQKRARKAMKNGKSPVVIDNTNIHAWEMKPYVMMARENRYEVIFREPDTPWKFNVRELTRKNIHGVPRQKIQQMKEEYEHYVTFHSVLHSEKPSREDRSSPDPYAAYGLGACANPPAAFSSRRPRMARTDNPVFY", "length": 251 }, "evidence": [ { "id": "Q29S05", "url": "https://omabrowser.org/oma/group/Q29S05/", "database": "OMA" } ], "glygen_name": "Chicken", "common_name": "Chicken" }, { "uniprot_canonical_ac": "Q3V2Q8-1", "protein_name": "NEDD4-binding protein 2-like 1", "gene_name": "N4bp2l1", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MEDSFLESFGRLSLQQRQQQPPPRPPPARGPPPRRHSFRKHLYLLRGLPGSGKTTLARQLQHDYPRALIFSTDDFFFKEDGTYEFNPNLLEEAHEWNQRRARKAMRNGISPIIIDNTNLHAWEMKPYAVMALENNYEVIFREPDTRWKFNVQELARRNIHGVPKEKIQRMKERYEHNVTFHSVLHAEKPSRANRNQGRNSEPSSGSGYWNTYTELPNRRANGLYSNEGYRRGGHHQGY", "length": 238 }, "evidence": [ { "id": "Q29S05", "url": "https://omabrowser.org/oma/group/Q29S05/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q5TBK1-1", "protein_name": "NEDD4-binding protein 2-like 1", "gene_name": "N4BP2L1", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MEDSFLQSFGRLSLQPQQQQQRQRPPRPPPRGTPPRRHSFRKHLYLLRGLPGSGKTTLARQLQHDFPRALIFSTDDFFFREDGAYEFNPDFLEEAHEWNQKRARKAMRNGISPIIIDNTNLHAWEMKPYAVMALENNYEVIFREPDTRWKFNVQELARRNIHGVSREKIHRMKERYEHDVTFHSVLHAEKPSRMNRNQDRNNALPSNNARYWNSYTEFPNRRAHGGFTNESSYHRRGGCHHGY", "length": 243 }, "evidence": [ { "id": "Q29S05", "url": "https://omabrowser.org/oma/group/Q29S05/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" } ], "go_annotation": {}, "pro_annotation": [], "site_annotation": [], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [ { "pdb_id": "AF-Q29S05-F1", "pdb_chain": "global", "start_pos": 1, "end_pos": 173, "overlap": "1.0", "method": "AlphaFold", "type": "alphafold", "resolution": -1.0, "url": "https://data.glygen.org/ln2downloads/pdb/current/AF-Q29S05-F1.pdb", "url_external": "https://alphafold.ebi.ac.uk/entry/Q29S05" } ], "lectin_list": [], "domain_list": [], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" }, { "name": "homologset.oma", "label": "OMA Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ], "tool_support": { "graph_view": "yes" } }, { "uniprot_canonical_ac": "Q0P5B9-1", "uniprot_ac": "Q0P5B9", "uniprot_id": "ANR39_BOVIN", "mass": { "chemical_mass": 19469.0, "monoisotopic_mass": 19469.0 }, "refseq": { "ac": "NP_001068939", "name": "ankyrin repeat domain-containing protein 39", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001068939" }, "gene_names": [ { "name": "ANKRD39", "type": "recommended", "evidence": [ { "id": "Q0P5B9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q0P5B9" } ] }, { "name": "ANKRD39", "type": "synonym", "evidence": [ { "id": "NP_001068939", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001068939" } ] } ], "protein_names": [ { "name": "Ankyrin repeat domain-containing protein 39", "type": "recommended", "evidence": [ { "id": "Q0P5B9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q0P5B9/entry#names_and_taxonomy" } ] }, { "name": "ankyrin repeat domain-containing protein 39", "type": "synonym", "evidence": [ { "id": "NP_001068939", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001068939" } ] } ], "function": [], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Bos taurus", "taxid": 9913, "evidence": [ { "database": "UniProtKB", "id": "Q0P5B9", "url": "https://www.uniprot.org/uniprotkb/Q0P5B9" } ], "common_name": "Bovine", "glygen_name": "Bovine", "reference_species": "Bos taurus [9913]" } ], "gene": [ { "name": "ANKRD39", "url": "https://www.uniprot.org/uniprotkb/Q0P5B9", "locus": { "chromosome": "11", "start_pos": 2807896, "end_pos": 2815289, "strand": "+", "evidence": [ { "database": "Ensembl Gene", "id": "ENSBTAG00000035244", "url": "https://www.ensembl.org/id/ENSBTAG00000035244" } ] } } ], "crossref": [ { "id": "Q0P5B9", "url": "https://alphafold.ebi.ac.uk/entry/Q0P5B9", "database": "AlphaFoldDB", "categories": [] }, { "id": "ENSBTAG00000035244", "url": "https://bgee.org/?page=gene&gene_id=ENSBTAG00000035244", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "510840", "url": "https://www.ncbi.nlm.nih.gov/gene/510840", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR002110", "url": "https://www.ebi.ac.uk/interpro/entry/IPR002110", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR036770", "url": "https://www.ebi.ac.uk/interpro/entry/IPR036770", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "bta:510840", "url": "https://www.genome.jp/dbget-bin/www_bget?bta:510840", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "A0A452DIF7", "url": "https://www.orthodb.org/?gene=A0A452DIF7", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "Q0P5B9", "url": "https://www.orthodb.org/?gene=Q0P5B9", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR24171", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR24171", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR24171:SF9", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR24171:SF9", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00023", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00023", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF12796", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF12796", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF13637", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF13637", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "NP_001068939", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001068939", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A452DIF7", "url": "https://www.uniprot.org/uniprotkb/A0A452DIF7", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A452DIF7-1", "url": "https://www.uniprot.org/uniprotkb/A0A452DIF7-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0AAA9SZR7", "url": "https://www.uniprot.org/uniprotkb/A0AAA9SZR7", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0AAA9SZR7-1", "url": "https://www.uniprot.org/uniprotkb/A0AAA9SZR7-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0AAA9T4V3", "url": "https://www.uniprot.org/uniprotkb/A0AAA9T4V3", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0AAA9T4V3-1", "url": "https://www.uniprot.org/uniprotkb/A0AAA9T4V3-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "Q0P5B9", "url": "https://www.uniprot.org/uniprotkb/Q0P5B9", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "Q0P5B9-1", "url": "https://www.uniprot.org/uniprotkb/Q0P5B9-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MAAPRPCADGPCCSHPSAAPGVQQTLDEMDFERGIWSAALNGDLGRVKYLIQKAVDPSQPDSAGYTALHYASRNGHYAVCQFLLESGAKCDAQTHGGATALHRASYCGHTDIARLLLSHGSNPRLVDADGMTSLHKAAEKGHVDICSLLLQHSPALKAVRDRKSRLACDLLPGNSDLRDLLAS", "length": 183, "header": "sp|Q0P5B9-1|ANR39_BOVIN Isoform 1 of Ankyrin repeat domain-containing protein 39 OS=Bos taurus OX=9913 GN=ANKRD39 PE=2 SV=1 CANONICAL=Q0P5B9-1" }, "isoforms": [ { "isoform_ac": "A0A452DIF7-1", "url": "https://www.uniprot.org/uniprotkb/A0A452DIF7/entry", "sequence": { "sequence": "MVRPGGTPRPRPGWPVAVPAPGSRWAGAESDMAAPRPCADGPCCSHPSAAPGMQQTLDEMDFERGIWSAALNGDLGRVKYLIQKAVDPSQPDSAGYTALHYASRNGHYAVCQFLLESGAKCDAQTHGGATALHRASYCGHTDIARLLLSHGSNPRLVDADGMTSLHKAAEKGHVDICSLLLQHSPALKAVRDRKSRLACDLLPGNSDLRDLLAS", "length": 214, "header": "tr|A0A452DIF7-1|ANR39_BOVIN Computationally mapped isoform of Ankyrin repeat domain-containing protein 39 OS=Bos taurus OX=9913 GN=ANKRD39 PE=2 SV=2 CANONICAL=Q0P5B9-1" }, "locus": { "chromosome": "11", "start_pos": 2815198, "end_pos": 2808888, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000014400.5", "url": "https://www.ensembl.org/id/ENSBTAT00000014400.5" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000014400.5", "url": "https://www.ensembl.org/id/ENSBTAP00000014400.5" } ] } }, { "isoform_ac": "A0AAA9SZR7-1", "url": "https://www.uniprot.org/uniprotkb/A0AAA9SZR7/entry", "sequence": { "sequence": "MRARRGPGARLAIETPARLQVEKQALASVTFRSGAAGSDSPPGATPGHPGPLRGLRGTGRQSLLPGYCTHPEGIWSAALNGDLGRVKYLIQKAVDPSQPDSAGYTALHYASRNGHYAVCQFLLESGAKCDAQTHGGATALHRASYCGHTDIARLLLSHGSNPRLVDADGMTSLHKAAEKGHVDICSLLLQHSPALKAVRDRKSRLACDLLPGNSDLRDLLAS", "length": 222, "header": "tr|A0AAA9SZR7-1|ANR39_BOVIN Computationally mapped isoform of Ankyrin repeat domain-containing protein 39 OS=Bos taurus OX=9913 GN=ANKRD39 PE=2 SV=1 CANONICAL=Q0P5B9-1" }, "locus": { "chromosome": "11", "start_pos": 2814837, "end_pos": 2808888, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000135719.1", "url": "https://www.ensembl.org/id/ENSBTAT00000135719.1" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000088873.1", "url": "https://www.ensembl.org/id/ENSBTAP00000088873.1" } ] } }, { "isoform_ac": "A0AAA9T4V3-1", "url": "https://www.uniprot.org/uniprotkb/A0AAA9T4V3/entry", "sequence": { "sequence": "MVRPGGTPRPRPGWPVAVPAPGSRWAGAESDMAAPRPCADGPCCSHPSAAPGMQQTLDEMDFERGIWSAALNGDLGRVKYLIQKAVDPSQPDSAGYTALHYASRNGHYAVCQFLLESGAKCDAQTHGGATALHRASYCGHTDIARLLLSHGSNPRLVDADGMTSLHKPEHQAQMLRDQLGALLCGDPCRLERQIAHFPVV", "length": 200, "header": "tr|A0AAA9T4V3-1|ANR39_BOVIN Computationally mapped isoform of Ankyrin repeat domain-containing protein 39 OS=Bos taurus OX=9913 GN=ANKRD39 PE=2 SV=1 CANONICAL=Q0P5B9-1" }, "locus": { "chromosome": "11", "start_pos": 2815198, "end_pos": 2810557, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000098975.1", "url": "https://www.ensembl.org/id/ENSBTAT00000098975.1" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000091535.1", "url": "https://www.ensembl.org/id/ENSBTAP00000091535.1" } ] } }, { "isoform_ac": "Q0P5B9-1", "url": "https://www.uniprot.org/uniprotkb/Q0P5B9/entry#Q0P5B9-1", "sequence": { "sequence": "MAAPRPCADGPCCSHPSAAPGVQQTLDEMDFERGIWSAALNGDLGRVKYLIQKAVDPSQPDSAGYTALHYASRNGHYAVCQFLLESGAKCDAQTHGGATALHRASYCGHTDIARLLLSHGSNPRLVDADGMTSLHKAAEKGHVDICSLLLQHSPALKAVRDRKSRLACDLLPGNSDLRDLLAS", "length": 183, "header": "sp|Q0P5B9-1|ANR39_BOVIN Isoform 1 of Ankyrin repeat domain-containing protein 39 OS=Bos taurus OX=9913 GN=ANKRD39 PE=2 SV=1 CANONICAL=Q0P5B9-1" }, "locus": {} } ], "glycosylation": [], "phosphorylation": [ { "start_pos": 153, "end_pos": 153, "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "residue": "Ser", "comment": "Phosphoserine", "evidence": [ { "database": "UniProtKB", "id": "Q0P5B9", "url": "https://www.uniprot.org/uniprotkb/Q0P5B9" } ], "site_lbl": "Ser153" } ], "glycation": [], "keywords": [], "publication": [], "pathway": [ { "id": "bta:510840", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?bta:510840", "resource": "KEGG Pathway" } ], "orthologs": [], "go_annotation": {}, "pro_annotation": [], "site_annotation": [], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [ { "pdb_id": "AF-Q0P5B9-F1", "pdb_chain": "global", "start_pos": 1, "end_pos": 183, "overlap": "1.0", "method": "AlphaFold", "type": "alphafold", "resolution": -1.0, "url": "https://data.glygen.org/ln2downloads/pdb/current/AF-Q0P5B9-F1.pdb", "url_external": "https://alphafold.ebi.ac.uk/entry/Q0P5B9" } ], "lectin_list": [], "domain_list": [], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [ 153 ], "sequon_annotation_sites": [] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 1 }, { "field": "total_sites", "count": 1 } ], "sort_fields": [ "start_pos", "end_pos", "kinase_uniprot_canonical_ac", "kinase_gene_name", "residue", "comment", "site_lbl" ] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ], "tool_support": { "graph_view": "yes" } }, { "uniprot_canonical_ac": "Q2TA00-1", "uniprot_ac": "Q2TA00", "uniprot_id": "CCD83_BOVIN", "mass": { "chemical_mass": 48938.0, "monoisotopic_mass": 48938.0 }, "refseq": { "ac": "NP_001033307", "name": "coiled-coil domain-containing protein 83", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001033307" }, "gene_names": [ { "name": "CCDC83", "type": "recommended", "evidence": [ { "id": "Q2TA00", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q2TA00" } ] }, { "name": "CCDC83", "type": "synonym", "evidence": [ { "id": "NP_001033307", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001033307" } ] } ], "protein_names": [ { "name": "Coiled-coil domain-containing protein 83", "type": "recommended", "evidence": [ { "id": "Q2TA00", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q2TA00/entry#names_and_taxonomy" } ] }, { "name": "coiled-coil domain-containing protein 83", "type": "synonym", "evidence": [ { "id": "NP_001033307", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001033307" } ] } ], "function": [], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Bos taurus", "taxid": 9913, "evidence": [ { "database": "UniProtKB", "id": "Q2TA00", "url": "https://www.uniprot.org/uniprotkb/Q2TA00" } ], "common_name": "Bovine", "glygen_name": "Bovine", "reference_species": "Bos taurus [9913]" } ], "gene": [ { "name": "CCDC83", "url": "https://www.uniprot.org/uniprotkb/Q2TA00", "locus": { "chromosome": "29", "start_pos": 9645537, "end_pos": 9697324, "strand": "+", "evidence": [ { "database": "Ensembl Gene", "id": "ENSBTAG00000011132", "url": "https://www.ensembl.org/id/ENSBTAG00000011132" } ] } } ], "crossref": [ { "id": "Q2TA00", "url": "https://alphafold.ebi.ac.uk/entry/Q2TA00", "database": "AlphaFoldDB", "categories": [] }, { "id": "ENSBTAG00000011132", "url": "https://bgee.org/?page=gene&gene_id=ENSBTAG00000011132", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "617342", "url": "https://www.ncbi.nlm.nih.gov/gene/617342", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR026702", "url": "https://www.ebi.ac.uk/interpro/entry/IPR026702", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "bta:617342", "url": "https://www.genome.jp/dbget-bin/www_bget?bta:617342", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "DMRIQIS", "url": "https://omabrowser.org/oma/group/DMRIQIS/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "A0A452DIG1", "url": "https://www.orthodb.org/?gene=A0A452DIG1", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "Q2TA00", "url": "https://www.orthodb.org/?gene=Q2TA00", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR21468", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR21468", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR21468:SF1", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR21468:SF1", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "NP_001033307", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001033307", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A452DIG1", "url": "https://www.uniprot.org/uniprotkb/A0A452DIG1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A452DIG1-1", "url": "https://www.uniprot.org/uniprotkb/A0A452DIG1-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "Q2TA00", "url": "https://www.uniprot.org/uniprotkb/Q2TA00", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "Q2TA00-1", "url": "https://www.uniprot.org/uniprotkb/Q2TA00-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "METAAKTNKRDIQDGPPKEVKLPISEALLDYHCQIKENALEQFMARIKKLREKNQKYHERNKRLKDEQIWHIRNLLKELSEEKSEGSVVVTREEVENAMKEKWKFERDQEQNLKDMRIQISNAEKLFLEKLSEKEYWEEYKNVGSEQHGKLITSLQNDINRVKENAEKMSEQYKITLEDARKRIIRETLLQLDQKKEWATENALRFIDKGSYREIWENDWLKKEIANHRKEVEELENAIHELEEENLVLIDQLFNCRLVDLKIPRRLYLTQAVGQEVPPEVPLELSETHKVIPEKSDSQPVDIKSRDVSSISFGSSGFRLSHKDSRFGQLLKIDEEASSSIEFGASDMKYLLYEDEQDFKDYVNLGPLEVKLMTVESKKMPIHFQEKETPVKFYEDVRSPESHITYKMMKSFL", "length": 413, "header": "sp|Q2TA00-1|CCD83_BOVIN Isoform 1 of Coiled-coil domain-containing protein 83 OS=Bos taurus OX=9913 GN=CCDC83 PE=2 SV=1 CANONICAL=Q2TA00-1" }, "isoforms": [ { "isoform_ac": "A0A452DIG1-1", "url": "https://www.uniprot.org/uniprotkb/A0A452DIG1/entry", "sequence": { "sequence": "METAAKTNKRDIQDGPPKEVKLPISEALLDYHCQIKENALERFMARIKKLREKNQKYHERNKRLKDEQIWHIRNLLKELSEEKSEGSVVVTREEVENAMKEKWKFERDQEQNLKDMRIQISNAEKLFLEKLSEKEYWEEYKNVGSEQHGKLITSLQNDINRVKENAEKMSEQYKITLEDARKRIIRETLLQLDQKKEWATENALRFIDKGSYREIWENDWLKKEIANHRKEVEELENAIHELEEENLVLIDQLFNCRLVDLKIPRRLYLTQAVGQEVPPEVPLELSETHKVIPEKSDSQPVDIKSRDVSSISFGSSGFRLSHKDSRFGQLLKIDEEASSSIEFGASDMKYLLYEDEQDFKDYVNLGPLEVKLMTVESKKMPIHFQEKETPVKFYEDVRSPESHITYKMMKSFL", "length": 413, "header": "tr|A0A452DIG1-1|CCD83_BOVIN Computationally mapped isoform of Coiled-coil domain-containing protein 83 OS=Bos taurus OX=9913 GN=CCDC83 PE=2 SV=1 CANONICAL=Q2TA00-1" }, "locus": { "chromosome": "29", "start_pos": 9691174, "end_pos": 9645674, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000014789.5", "url": "https://www.ensembl.org/id/ENSBTAT00000014789.5" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000014789.4", "url": "https://www.ensembl.org/id/ENSBTAP00000014789.4" } ] } }, { "isoform_ac": "Q2TA00-1", "url": "https://www.uniprot.org/uniprotkb/Q2TA00/entry#Q2TA00-1", "sequence": { "sequence": "METAAKTNKRDIQDGPPKEVKLPISEALLDYHCQIKENALEQFMARIKKLREKNQKYHERNKRLKDEQIWHIRNLLKELSEEKSEGSVVVTREEVENAMKEKWKFERDQEQNLKDMRIQISNAEKLFLEKLSEKEYWEEYKNVGSEQHGKLITSLQNDINRVKENAEKMSEQYKITLEDARKRIIRETLLQLDQKKEWATENALRFIDKGSYREIWENDWLKKEIANHRKEVEELENAIHELEEENLVLIDQLFNCRLVDLKIPRRLYLTQAVGQEVPPEVPLELSETHKVIPEKSDSQPVDIKSRDVSSISFGSSGFRLSHKDSRFGQLLKIDEEASSSIEFGASDMKYLLYEDEQDFKDYVNLGPLEVKLMTVESKKMPIHFQEKETPVKFYEDVRSPESHITYKMMKSFL", "length": 413, "header": "sp|Q2TA00-1|CCD83_BOVIN Isoform 1 of Coiled-coil domain-containing protein 83 OS=Bos taurus OX=9913 GN=CCDC83 PE=2 SV=1 CANONICAL=Q2TA00-1" }, "locus": {} } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [ { "id": "bta:617342", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?bta:617342", "resource": "KEGG Pathway" } ], "orthologs": [ { "uniprot_canonical_ac": "A0A4X1U7C6-1", "protein_name": "Coiled-coil domain containing 83", "gene_name": "CCDC83", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MENTAKANKKDIQDGPPKEVKLPTSEALLDYHCQIKENAVERFMVQIKKLREKNQKYQERNKRLKDEQTWHIRNLLKELSEDKSEGSTVVTREEVERAMKEKWKFERDQEQNLKDMHIQINNAEKLFLEKLSEKEYWEQYKNVGSEQQAKLIIALQNDINRVKENAEKMSEQYDINLEDVRKRIIRETLLQLDQKKEWATENALRFIDKGSYREIWENDWLKKEIATHRKEVEELEHAIHELEGENLVLIDQLFNCRLVDLKIPRRLYLTQAVGQEVPPEEMPLELPETSIEKSQLQPVEVKSRDLISLSLGSSSLPLGHEDSSRYSEQLKTDEEESSSIAFGASDIKYLLYEDEQDFKDYVNLGPLEVKLMTVESKKKPIHFQEKEIPVKFYEDVRSPESHITYKMMKSFL", "length": 412 }, "evidence": [ { "id": "Q2TA00", "url": "https://omabrowser.org/oma/group/Q2TA00/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "A0ABK0LMB0-1", "protein_name": "Coiled-coil domain containing 83", "gene_name": "Ccdc83", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MDSSAKGSKKDAPDGPPKDSKMPVSEALLDYHREIKENAVERFTFHIRKLRDKNQKYLERNRRLKEEQNWHLKNLIKELKDEKLDVVQPITREDVEEAMKEKWKFERDQEAHLKEMRVQISEAEKLFLEKLSEKEYWEEYKNVGSAQHAELILSLQNDIDTVKENAEKMSEQYKVTLEDTRKKIIRETLILLEQRKEWATQNAVRFIDKNNYREIWENDWLKKEIKIHRKEVEELETCIHQLEEENLLLIEQLFNCRLVDLKIPRKLYITQAAGLQVTPEDESLNLPDANTAPEENLQLPSKEESDDRLDLLLGSSYGISSPDSQPKKTGSKEGSCTEIEDPIVKYLVQEDEQDFKEYVNLGPLALKLMSVQGKKMPIHFQEKEMPIEFYEDMRNPESHITHKMMKTFL", "length": 409 }, "evidence": [ { "id": "Q2TA00", "url": "https://omabrowser.org/oma/group/Q2TA00/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "Q8IWF9-1", "protein_name": "Coiled-coil domain-containing protein 83", "gene_name": "CCDC83", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MENSGKANKKDTHDGPPKEIKLPTSEALLDYQCQIKEDAVEQFMFQIKTLRKKNQKYHERNSRLKEEQIWHIRHLLKELSEEKAEGLPVVTREDVEEAMKEKWKFERDQEKNLRDMRMQISNAEKLFLEKLSEKEYWEEYKNVGSERHAKLITSLQNDINTVKENAEKMSEHYKITLEDTRKKIIKETLLQLDQKKEWATQNAVKLIDKGSYLEIWENDWLKKEVAIHRKEVEELKNAIHELEAENLVLIDQLSNCRLVDLKIPRRLYLTQAAGLEVPPEEMSLELPETHIEEKSELQPTEVESRDLMSSSDESTILHLSHENSIEDLQYVKIDKEENSGTEFGDTDMKYLLYEDEKDFKDYVNLGPLGVKLMSVESKKMPIHFQEKEIPVKLYKDVRSPESHITYKMMKSFL", "length": 413 }, "evidence": [ { "id": "Q2TA00", "url": "https://omabrowser.org/oma/group/Q2TA00/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "Q9D4V3-1", "protein_name": "Coiled-coil domain-containing protein 83", "gene_name": "Ccdc83", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MDSSAKGSKKDAPDGPPKDSKLPVSEALLDYHREIKENAVERFMFHIKKLREKNQKYQERNRRLKEEQNWHIKNLIKELKEKNLDEAPIVTREEVEEAMKEKWEFERQQEASLKEMRIQINEAEKLFLEKLSEKEYWEEYKNVGSAQHAQLIVSLQNDIDTVKENAEKMSEQYKVTLEDEKKRISRETMIQLKQRKEWATQHAVRFIDKNNYREIWENDWLKKEGDTASFGNVLSLLDFLPPDLHTAEPCVSSGQSRGSLRILAPFALQLWSKLSGLLPTLVTPDPVCIIWSFGPGQTNSMAICP", "length": 305 }, "evidence": [ { "id": "Q2TA00", "url": "https://omabrowser.org/oma/group/Q2TA00/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" } ], "go_annotation": {}, "pro_annotation": [], "site_annotation": [], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [ { "pdb_id": "AF-Q2TA00-F1", "pdb_chain": "global", "start_pos": 1, "end_pos": 413, "overlap": "1.0", "method": "AlphaFold", "type": "alphafold", "resolution": -1.0, "url": "https://data.glygen.org/ln2downloads/pdb/current/AF-Q2TA00-F1.pdb", "url_external": "https://alphafold.ebi.ac.uk/entry/Q2TA00" } ], 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"total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ], "tool_support": { "graph_view": "yes" } }, { "uniprot_canonical_ac": "Q3T146-1", "uniprot_ac": "Q3T146", "uniprot_id": "CE046_BOVIN", "mass": { "chemical_mass": 9735.0, "monoisotopic_mass": 9735.0 }, "refseq": { "ac": "NP_001193263", "name": "uncharacterized protein C5orf46 homolog precursor", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001193263" }, "gene_names": [ { "name": "C7H5orf46", "type": "recommended", "evidence": [ { "id": "Q3T146", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q3T146" } ] }, { "name": "C7H5orf46", "type": "synonym", "evidence": [ { "id": "NP_001193263", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001193263" } ] } ], "protein_names": [ { "name": "Uncharacterized protein C5orf46 homolog", "type": "recommended", "evidence": [ { "id": "Q3T146", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q3T146/entry#names_and_taxonomy" } ] }, { "name": "uncharacterized protein C5orf46 homolog precursor", "type": "synonym", "evidence": [ { "id": "NP_001193263", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001193263" } ] }, { "name": "uncharacterized protein C5orf46 homolog", "type": "synonym", "evidence": [ { "id": "NP_001193263", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001193263" } ] } ], "function": [], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Bos taurus", "taxid": 9913, "evidence": [ { "database": "UniProtKB", "id": "Q3T146", "url": "https://www.uniprot.org/uniprotkb/Q3T146" } ], "common_name": "Bovine", "glygen_name": "Bovine", "reference_species": "Bos taurus [9913]" } ], "gene": [ { "name": "", "url": "https://www.uniprot.org/uniprotkb/Q3T146", "locus": {} } ], "crossref": [ { "id": "Q3T146", "url": "https://alphafold.ebi.ac.uk/entry/Q3T146", "database": "AlphaFoldDB", "categories": [] }, { "id": "614113", "url": "https://www.ncbi.nlm.nih.gov/gene/614113", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR027950", "url": "https://www.ebi.ac.uk/interpro/entry/IPR027950", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "bta:614113", "url": "https://www.genome.jp/dbget-bin/www_bget?bta:614113", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "FQMYLNN", "url": "https://omabrowser.org/oma/group/FQMYLNN/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "A0A452DIP0", "url": "https://www.orthodb.org/?gene=A0A452DIP0", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "Q3T146", "url": "https://www.orthodb.org/?gene=Q3T146", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR37864", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR37864", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR37864:SF1", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR37864:SF1", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF15144", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF15144", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "NP_001193263", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001193263", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A452DIP0", "url": "https://www.uniprot.org/uniprotkb/A0A452DIP0", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A452DIP0-1", "url": "https://www.uniprot.org/uniprotkb/A0A452DIP0-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "Q3T146", "url": "https://www.uniprot.org/uniprotkb/Q3T146", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "Q3T146-1", "url": "https://www.uniprot.org/uniprotkb/Q3T146-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MAVSGLRLTIVWGLLVLILTCQADDKPEGKPDEQPHDSGKNSEPAFPKFLNILGSDIIENAVEFILRSMTRSTEFLEHGDKQGEHSSK", "length": 88, "header": "sp|Q3T146-1|CE046_BOVIN Isoform 1 of Uncharacterized protein C5orf46 homolog OS=Bos taurus OX=9913 GN= PE=3 SV=1 CANONICAL=Q3T146-1" }, "isoforms": [ { "isoform_ac": "A0A452DIP0-1", "url": "https://www.uniprot.org/uniprotkb/A0A452DIP0/entry", "sequence": { "sequence": "MHRNNFSASIPTATNMAVSGLRLTIVWGLLVLILTCQADDKPEGKPDEQPHDSGKNSEPAFPKFLNILGSDIIENAVEFILRSMTRSTEFLEHGDKQGEHSSK", "length": 103, "header": "tr|A0A452DIP0-1|CE046_BOVIN Computationally mapped isoform of Uncharacterized protein C5orf46 homolog OS=Bos taurus OX=9913 GN= PE=3 SV=1 CANONICAL=Q3T146-1" }, "locus": {} }, { "isoform_ac": "Q3T146-1", "url": "https://www.uniprot.org/uniprotkb/Q3T146/entry#Q3T146-1", "sequence": { "sequence": "MAVSGLRLTIVWGLLVLILTCQADDKPEGKPDEQPHDSGKNSEPAFPKFLNILGSDIIENAVEFILRSMTRSTEFLEHGDKQGEHSSK", "length": 88, "header": "sp|Q3T146-1|CE046_BOVIN Isoform 1 of Uncharacterized protein C5orf46 homolog OS=Bos taurus OX=9913 GN= PE=3 SV=1 CANONICAL=Q3T146-1" }, "locus": { "chromosome": "7", "start_pos": 59146713, "end_pos": 59137198, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000020555.8", "url": "https://www.ensembl.org/id/ENSBTAT00000020555.8" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000020555.7", "url": "https://www.ensembl.org/id/ENSBTAP00000020555.7" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [ { "id": "bta:614113", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?bta:614113", "resource": "KEGG Pathway" } ], "orthologs": [ { "uniprot_canonical_ac": "D3ZIS7-1", "protein_name": "Similar to human chromosome 5 open reading frame 46", "gene_name": "C18h5orf46", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MAVSVLRLMVVLGLSALILTCWADDNPNDNDHLDEKSDKPDDSKNPEPGFPKFLSILGSEIIENAVDFILRSMSRGSSFMELEGDPGQQPSKVTS", "length": 95 }, "evidence": [ { "id": "Q3T146", "url": "https://omabrowser.org/oma/group/Q3T146/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "Q3V2D2-1", "protein_name": "Uncharacterized protein C5orf46 homolog", "gene_name": "Gm94", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MAVSVLRLMVVLGLSALILTCRADDNPNENDNPDSKPDDSSKNPEPGFPKFLSILGSEIIENAVDFILRSMSRGSSFMELEGDPGQQPSKVTS", "length": 93 }, "evidence": [ { "id": "Q3T146", "url": "https://omabrowser.org/oma/group/Q3T146/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q6UWT4-1", "protein_name": "Uncharacterized protein C5orf46", "gene_name": "C5orf46", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MAVSVLRLTVVLGLLVLFLTCYADDKPDKPDDKPDDSGKDPKPDFPKFLSLLGTEIIENAVEFILRSMSRSTGFMEFDDNEGKHSSK", "length": 87 }, "evidence": [ { "id": "Q3T146", "url": "https://omabrowser.org/oma/group/Q3T146/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" } ], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 1, "go_terms": [ { "name": "extracellular region", "id": "GO:0005576", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005576", "evidence": [ { "database": "UniProtKB", "id": "Q3T146", "url": "https://www.uniprot.org/uniprotkb/Q3T146" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [ { "pdb_id": "AF-Q3T146-F1", "pdb_chain": "global", "start_pos": 1, "end_pos": 88, "overlap": "1.0", "method": "AlphaFold", "type": "alphafold", "resolution": -1.0, "url": "https://data.glygen.org/ln2downloads/pdb/current/AF-Q3T146-F1.pdb", "url_external": "https://alphafold.ebi.ac.uk/entry/Q3T146" } ], "lectin_list": [], "domain_list": [], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" }, { "name": "homologset.oma", "label": "OMA Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [] }, "class_list": [], 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"table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { 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"P02694", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P02694/entry#names_and_taxonomy" } ] }, { "name": "CRBP-I", "type": "synonym", "evidence": [ { "id": "NP_001020514", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001020514" }, { "id": "P02694", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P02694/entry#names_and_taxonomy" } ] }, { "name": "CRBP", "type": "synonym", "evidence": [ { "id": "NP_001020514", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001020514" }, { "id": "P02694", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P02694/entry#names_and_taxonomy" } ] }, { "name": "Cellular retinol-binding protein I", "type": "synonym", "evidence": [ { "id": "P02694", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P02694/entry#names_and_taxonomy" } ] }, { "name": "Cellular retinol-binding protein", "type": "synonym", "evidence": [ { "id": "P02694", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P02694/entry#names_and_taxonomy" } ] }, { "name": "cellular retinol binding protein 1", "type": "synonym", "evidence": [ { "id": "NP_001020514", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001020514" } ] }, { "name": "cellular retinol-binding protein I", "type": "synonym", "evidence": [ { "id": "NP_001020514", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001020514" } ] }, { "name": "retinol binding protein 1, cellular", "type": "synonym", "evidence": [ { "id": "NP_001020514", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001020514" } ] }, { "name": "retinol-binding protein 1", "type": "synonym", "evidence": [ { "id": "NP_001020514", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001020514" } ] } ], "function": [ { "annotation": "Cytoplasmic retinol-binding protein (PubMed:7744071). Accepts retinol from the transport protein STRA6, and thereby contributes to retinol uptake, storage and retinoid homeostasis.", "evidence": [ { "database": "UniProtKB", "id": "P02694", "url": "https://www.uniprot.org/uniprotkb/P02694#function" }, { "database": "UniProtKB", "id": "P09455", "url": "https://www.uniprot.org/uniprotkb/P09455#function" }, { "database": "PubMed", "id": "7744071", "url": "https://glygen.org/publication/PubMed/7744071" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Bos taurus", "taxid": 9913, "evidence": [ { "database": "UniProtKB", "id": "P02694", "url": "https://www.uniprot.org/uniprotkb/P02694" } ], "common_name": "Bovine", "glygen_name": "Bovine", "reference_species": "Bos taurus [9913]" } ], "gene": [ { "name": "RBP1", "url": "https://www.uniprot.org/uniprotkb/P02694", "locus": { "chromosome": "1", "start_pos": 129583702, "end_pos": 129556625, "strand": "-", "evidence": [ { "database": "Ensembl Gene", "id": "ENSBTAG00000020028", "url": "https://www.ensembl.org/id/ENSBTAG00000020028" } ] } } ], "crossref": [ { "id": "P02694", "url": "https://alphafold.ebi.ac.uk/entry/P02694", "database": "AlphaFoldDB", "categories": [] }, { "id": "ENSBTAG00000020028", "url": "https://bgee.org/?page=gene&gene_id=ENSBTAG00000020028", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "cd19462", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd19462", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "537379", "url": "https://www.ncbi.nlm.nih.gov/gene/537379", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR000463", "url": "https://www.ebi.ac.uk/interpro/entry/IPR000463", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR000566", "url": "https://www.ebi.ac.uk/interpro/entry/IPR000566", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR012674", "url": "https://www.ebi.ac.uk/interpro/entry/IPR012674", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR031259", "url": "https://www.ebi.ac.uk/interpro/entry/IPR031259", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR031264", "url": "https://www.ebi.ac.uk/interpro/entry/IPR031264", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "bta:537379", "url": "https://www.genome.jp/dbget-bin/www_bget?bta:537379", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "A0A452DJ95", "url": "https://www.orthodb.org/?gene=A0A452DJ95", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "P02694", "url": "https://www.orthodb.org/?gene=P02694", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR11955", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR11955", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00061", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00061", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "R-BTA-2453902", "url": "https://www.reactome.org/PathwayBrowser/#R-BTA-2453902", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "R-BTA-975634", "url": "https://www.reactome.org/PathwayBrowser/#R-BTA-975634", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "NP_001020514", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001020514", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A452DJ95", "url": "https://www.uniprot.org/uniprotkb/A0A452DJ95", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A452DJ95-1", "url": "https://www.uniprot.org/uniprotkb/A0A452DJ95-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0AAA9TFY6", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TFY6", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0AAA9TFY6-1", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TFY6-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0AAA9TMV4", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TMV4", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0AAA9TMV4-1", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TMV4-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0ABI0NK90", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NK90", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0ABI0NK90-1", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NK90-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0ABI0NN40", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NN40", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0ABI0NN40-1", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NN40-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0ABI0NQ20", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NQ20", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0ABI0NQ20-1", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NQ20-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0ABI0NRG8", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NRG8", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0ABI0NRG8-1", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NRG8-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0ABI0P0H4", "url": "https://www.uniprot.org/uniprotkb/A0ABI0P0H4", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0ABI0P0H4-1", "url": "https://www.uniprot.org/uniprotkb/A0ABI0P0H4-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0ABI0P3E0", "url": "https://www.uniprot.org/uniprotkb/A0ABI0P3E0", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0ABI0P3E0-1", "url": "https://www.uniprot.org/uniprotkb/A0ABI0P3E0-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "P02694", "url": "https://www.uniprot.org/uniprotkb/P02694", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "P02694-1", "url": "https://www.uniprot.org/uniprotkb/P02694-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MPVDFTGYWKMLANENFEEYLRALDVNVALRKIANLLKPDKEIVQEGDHMIIRTLSTFRNYIMDFQVGKEFEEDLTGIDDRKCMTTVSWDGDKLECVQKGEKEGRGWTQWIEGDELHLEMRVEGVVCKQVFKKVN", "length": 135, "header": "sp|P02694-1|RET1_BOVIN Isoform 1 of Retinol-binding protein 1 OS=Bos taurus OX=9913 GN=RBP1 PE=1 SV=4 CANONICAL=P02694-1" }, "isoforms": [ { "isoform_ac": "A0A452DJ95-1", "url": "https://www.uniprot.org/uniprotkb/A0A452DJ95/entry", "sequence": { "sequence": "MPVDFTGYWKMLANENFEEYLRALDVNVALRKIANLLKPDKEIVQEGDHMIIRTLSTFRNYIMDFQVGKEFEEDLTGIDDRKCMPRPEGAAVEEGSKPPVNKDGKLVTWRPQLAPPRCLRKTTVSWDGDKLECVQKGEKEGRGWTQWIEGDELHLEMRVEGVVCKQVFKKVN", "length": 172, "header": "tr|A0A452DJ95-1|RET1_BOVIN Computationally mapped isoform of Retinol-binding protein 1 OS=Bos taurus OX=9913 GN=RBP1 PE=1 SV=2 CANONICAL=P02694-1" }, "locus": { "chromosome": "1", "start_pos": 129583513, "end_pos": 129556881, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000015936.5", "url": "https://www.ensembl.org/id/ENSBTAT00000015936.5" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000015936.5", "url": "https://www.ensembl.org/id/ENSBTAP00000015936.5" } ] } }, { "isoform_ac": "A0AAA9TFY6-1", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TFY6/entry", "sequence": { "sequence": "MPVDFTGYWKMLANENFEEYLRALDVNVALRKIANLLKPDKEIVQEGDHMIIRTLSTFRNYIMDFQVGKEFEEDLTGIDDRKCMPRPEGAAVEEGSKPPVNKDGKLVTWRPQLAPPRCLRKVQVQRLGFLLLSVWPSAHPVPVVAHEAQGRRESSKTTVSWDGDKLECVQKGEKEGRGWTQWIEGDELHLEMRVEGVVCKQVFKKVN", "length": 207, "header": "tr|A0AAA9TFY6-1|RET1_BOVIN Computationally mapped isoform of Retinol-binding protein 1 OS=Bos taurus OX=9913 GN=RBP1 PE=1 SV=1 CANONICAL=P02694-1" }, "locus": { "chromosome": "1", "start_pos": 129583513, "end_pos": 129556881, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000115958.1", "url": "https://www.ensembl.org/id/ENSBTAT00000115958.1" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000095762.1", "url": "https://www.ensembl.org/id/ENSBTAP00000095762.1" } ] } }, { "isoform_ac": "A0AAA9TMV4-1", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TMV4/entry", "sequence": { "sequence": "MPVDFTGYWKMLANENFEEYLRALDVNVALRKIANLLKPDKEIVQEGDHMIIRTLSTFRNYIMDFQVGKEFEEDLTGIDDRKCMHHLLQEAFPDGPLSPLQSLMRGSRHQKASGHQAALQGLLLDPSLLEGKVLLKHLAMTTVSWDGDKLECVQKGEKEGRGWTQWIEGDELHLEMRVEGVVCKQVFKKVN", "length": 191, "header": "tr|A0AAA9TMV4-1|RET1_BOVIN Computationally mapped isoform of Retinol-binding protein 1 OS=Bos taurus OX=9913 GN=RBP1 PE=1 SV=1 CANONICAL=P02694-1" }, "locus": { "chromosome": "1", "start_pos": 129583513, "end_pos": 129556881, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000101034.1", "url": "https://www.ensembl.org/id/ENSBTAT00000101034.1" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000099690.1", "url": "https://www.ensembl.org/id/ENSBTAP00000099690.1" } ] } }, { "isoform_ac": "A0ABI0NK90-1", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NK90/entry", "sequence": { "sequence": "MPVDFTGYWKMLANENFEEYLRALDVNVALRKIANLLKPDKEIVQEGDHMIIRTLSTFRNYIMDFQVGKEFEEDLTGIDDRKCMVQVQRLGFLLLSVWPSAHPVPVVAHEAQGRRESSKTTVSWDGDKLECVQKGEKEGRGWTQWIEGDELHLEMRVEGVVCKQVFKKVN", "length": 170, "header": "tr|A0ABI0NK90-1|A0ABI0NK90_BOVIN Computationally mapped isoform of Retinol binding protein 1 OS=Bos taurus OX=9913 GN=RBP1 PE=3 SV=1 CANONICAL=P02694-1" }, "locus": { "chromosome": "1", "start_pos": 129583513, "end_pos": 129556881, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000140279.1", "url": "https://www.ensembl.org/id/ENSBTAT00000140279.1" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000105065.1", "url": "https://www.ensembl.org/id/ENSBTAP00000105065.1" } ] } }, { "isoform_ac": "A0ABI0NN40-1", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NN40/entry", "sequence": { "sequence": "MPVDFTGYWKMLANENFEEYLRALDVNVALRKIANLLKPDKEIVQEGDHMIIRTLSTFRNYIMDFQVGKEFEEDLTGIDDRKCMTTVSWDGDKLECVQKGEKEGRGWTQWIEGDELHLEMRVEGVVCKQVFKKEGHEAYHACKTCGLPSTRPVALRLG", "length": 158, "header": "tr|A0ABI0NN40-1|A0ABI0NN40_BOVIN Computationally mapped isoform of Retinol binding protein 1 OS=Bos taurus OX=9913 GN=RBP1 PE=3 SV=1 CANONICAL=P02694-1" }, "locus": { "chromosome": "1", "start_pos": 129584689, "end_pos": 129556881, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000137101.1", "url": "https://www.ensembl.org/id/ENSBTAT00000137101.1" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000106992.1", "url": "https://www.ensembl.org/id/ENSBTAP00000106992.1" } ] } }, { "isoform_ac": "A0ABI0NQ20-1", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NQ20/entry", "sequence": { "sequence": "MPVDFTGYWKMLANENFEEYLRALDVNVALRKIANLLKPDKEIVQEGDHMIIRTLSTFRNYIMDFQVGKEFEEDLTGIDDRKCMADGWRHSDLWSPGSLSSHFQPVLFRSLHDCKQSGLSSWWKCVKPGSSFSPPPPACLYPLK", "length": 144, "header": "tr|A0ABI0NQ20-1|A0ABI0NQ20_BOVIN Computationally mapped isoform of Retinol binding protein 1 OS=Bos taurus OX=9913 GN=RBP1 PE=3 SV=1 CANONICAL=P02694-1" }, "locus": { "chromosome": "1", "start_pos": 129562927, "end_pos": 129556881, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000147196.1", "url": "https://www.ensembl.org/id/ENSBTAT00000147196.1" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000104210.1", "url": "https://www.ensembl.org/id/ENSBTAP00000104210.1" } ] } }, { "isoform_ac": "A0ABI0NRG8-1", "url": "https://www.uniprot.org/uniprotkb/A0ABI0NRG8/entry", "sequence": { "sequence": "MPVDFTGYWKMLANENFEEYLRALDVNVALRKIANLLKPDKEIVQEGDHMIIRTLSTFRNYIMDFQVGKEFEEDLTGIDDRKCMGKQTSEGFRAPGSPAGSPLGSKSSGREGASETFSHDHGELGWGQARVCTEGREGGTWLDPVD", "length": 146, "header": "tr|A0ABI0NRG8-1|A0ABI0NRG8_BOVIN Computationally mapped isoform of Retinol binding protein 1 OS=Bos taurus OX=9913 GN=RBP1 PE=3 SV=1 CANONICAL=P02694-1" }, "locus": { "chromosome": "1", "start_pos": 129581068, "end_pos": 129556881, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000152644.1", "url": "https://www.ensembl.org/id/ENSBTAT00000152644.1" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000105198.1", "url": "https://www.ensembl.org/id/ENSBTAP00000105198.1" } ] } }, { "isoform_ac": "A0ABI0P0H4-1", "url": "https://www.uniprot.org/uniprotkb/A0ABI0P0H4/entry", "sequence": { "sequence": "MPVDFTGYWKMLANENFEEYLRALDVNVALRKIANLLKPDKEIVQEGDHMIIRTLSTFRNYIMDFQVGKEFEEDLTGIDDRKCMTTVSWDGDKLECVQKGEKEGRGWTQWIEGDELHLRLSCVSLEKKLSPCFITVP", "length": 137, "header": "tr|A0ABI0P0H4-1|A0ABI0P0H4_BOVIN Computationally mapped isoform of Retinol binding protein 1 OS=Bos taurus OX=9913 GN=RBP1 PE=3 SV=1 CANONICAL=P02694-1" }, "locus": { "chromosome": "1", "start_pos": 129581967, "end_pos": 129556881, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000142203.1", "url": "https://www.ensembl.org/id/ENSBTAT00000142203.1" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000107240.1", "url": "https://www.ensembl.org/id/ENSBTAP00000107240.1" } ] } }, { "isoform_ac": "A0ABI0P3E0-1", "url": "https://www.uniprot.org/uniprotkb/A0ABI0P3E0/entry", "sequence": { "sequence": "MPVDFTGYWKMLANENFEEYLRALDVNVALRKIANLLKPDKEIVQEGDHMIIRTLSTFRNYIMDFQVGKEFEEDLTGIDDRKCMPRPEGAAVEEGSKPPVNKDGKLVTWRPQLAPPRCLRKTTVSWDGDKLECVQKGEKEGRGWTQWIEGDELHLVLLGGAFFLSTSSGKHHPTTKGFCRDQDL", "length": 184, "header": "tr|A0ABI0P3E0-1|A0ABI0P3E0_BOVIN Computationally mapped isoform of Retinol binding protein 1 OS=Bos taurus OX=9913 GN=RBP1 PE=3 SV=1 CANONICAL=P02694-1" }, "locus": { "chromosome": "1", "start_pos": 129582491, "end_pos": 129556881, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000149508.1", "url": "https://www.ensembl.org/id/ENSBTAT00000149508.1" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000105975.1", "url": "https://www.ensembl.org/id/ENSBTAP00000105975.1" } ] } }, { "isoform_ac": "P02694-1", "url": "https://www.uniprot.org/uniprotkb/P02694/entry#P02694-1", "sequence": { "sequence": "MPVDFTGYWKMLANENFEEYLRALDVNVALRKIANLLKPDKEIVQEGDHMIIRTLSTFRNYIMDFQVGKEFEEDLTGIDDRKCMTTVSWDGDKLECVQKGEKEGRGWTQWIEGDELHLEMRVEGVVCKQVFKKVN", "length": 135, "header": "sp|P02694-1|RET1_BOVIN Isoform 1 of Retinol-binding protein 1 OS=Bos taurus OX=9913 GN=RBP1 PE=1 SV=4 CANONICAL=P02694-1" }, "locus": {} } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [ { "title": "N-terminal sequence homology among retinoid-binding proteins from bovine retina.", "journal": "FEBS Lett.", "date": "1981", "authors": "Crabb J W, Saari J C", "evidence": [ { "database": "UniProtKB", "id": "P02694", "url": "https://www.uniprot.org/uniprotkb/P02694" } ], "reference": [ { "type": "PubMed", "id": "6269887", "url": "https://glygen.org/publication/PubMed/6269887" } ] }, { "title": "Interactions with retinol and retinoids of bovine cellular retinol-binding protein.", "journal": "European journal of biochemistry", "date": "1995-04-15", "authors": "Malpeli G, Stoppini M, Zapponi M C, Folli C, Berni R", "evidence": [ { "database": "UniProtKB", "id": "P02694", "url": "https://www.uniprot.org/uniprotkb/P02694" } ], "reference": [ { "type": "PubMed", "id": "7744071", "url": "https://glygen.org/publication/PubMed/7744071" } ] } ], "pathway": [ { "id": "bta:537379", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?bta:537379", "resource": "KEGG Pathway" }, { "id": "R-BTA-2453902", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-BTA-2453902", "resource": "Reactome", "description": "The canonical retinoid cycle in rods (twilight vision)" }, { "id": "R-BTA-975634", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-BTA-975634", "resource": "Reactome", "description": "Retinoid metabolism and transport" } ], "orthologs": [], "go_annotation": { "categories": [ { "name": "Molecular Function", "total": 4, "go_terms": [ { "name": "fatty acid binding", "id": "GO:0005504", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005504", "evidence": [ { "database": "UniProtKB", "id": "P02694", "url": "https://www.uniprot.org/uniprotkb/P02694" } ], "pmid": "" }, { "name": "retinal binding", "id": "GO:0016918", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016918", "evidence": [ { "database": "UniProtKB", "id": "P02694", "url": "https://www.uniprot.org/uniprotkb/P02694" } ], "pmid": "" }, { "name": "all-trans-retinol binding", "id": "GO:1904768", "url": 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"length": 129 }, "evidence": [ { "id": "Q32PB5", "url": "https://omabrowser.org/oma/group/Q32PB5/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "Q8C5S3-1", "protein_name": "Uncharacterized protein C3orf22 homolog", "gene_name": "", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MDSKGHKKPCRHKKKEIKTYERFVKKFPYRLPHLTEPSTSCPPSCKAKSNSLKDKLPLQKNLVPTRSIPIPGLGAPQVAWPFSFYSPPPHPPLCNLWELKLLQLRFPTQDLPRLPPLQTPDNQPLTSGISKPPESIP", "length": 137 }, "evidence": [ { "id": "Q32PB5", "url": "https://omabrowser.org/oma/group/Q32PB5/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q8N5N4-1", "protein_name": "Uncharacterized protein C3orf22", "gene_name": "C3orf22", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MDSSACKKSHQSKKWRIQAQENFAKKFPYRLSWLTEPDPEPLQPWEVTNDSNTVQLPLQKRLVPTRSIPVRGLGAPDFTSPSGSCPAPLPAPSPPPLCNLWELKLLSRRFPRQLAFLLSTRHTEAACPQTSKAAGLSRGLS", 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"MACEPQMDPGGAAGPLPTSSPGWSPLPGGSPPGWGQELRSGQVLTVLRIDNTCAPISFDLGAAEEQLQTWGIQVPADQYRSLAESALLEPQVRRYIIYNSRPMRLAFAVVFYVVVWANIYSTSQMFALGNHWAGVLLVTLAATSLTLTLVVIFERHQRKANTNTDLRLTAANGALLRHRVLLGVTDTVEGCQSVIQLWFVYFDLETCAQFLSDHIREMKMSQESLLRSRLSQLCVVMETGVSPTANEGPENLLEETPLLPDRPGSTEKPLMQTELRQLVPEAEPEEMAQQLLAVFGGYYTRLLVTSQLPQALGTRHMDSPRIPCPCQLIEAYILGTECCPFLTR", "length": 344, "header": "sp|Q5EA48-1|TM268_BOVIN Isoform 1 of Transmembrane protein 268 OS=Bos taurus OX=9913 GN=TMEM268 PE=2 SV=1 CANONICAL=Q5EA48-1" }, "isoforms": [ { "isoform_ac": "A0A452DJG3-1", "url": "https://www.uniprot.org/uniprotkb/A0A452DJG3/entry", "sequence": { "sequence": "MACEPQMDPGGAAGPLPTSSPGWSPLPGGSPPGWGQELRSGQVLTVLRIDNTCAPISFDLGAAEEQLQTWGIQVPADQYRSLAESALLEPQVRRYIIYNSRPMRLAFAVVFYVVVWANIYSTSQMFAGNHWAGVLLVTLAATSLTLTLVVIFERHQRKANTNTDLRLTAANGALLRHRVLLGVTDTVEGCQSVIQLWFVYFDLETCAQFLSDHIREMKMSQESLLRSRLSQLCVVMETGVSPTANEGPENLLEETPLLPDRPGSTEKPLMQTELRQLVPEAEPEEMAQQLLAVFGGYYTRLLVTSQLPQALGTRHMDSPRIPCPCQLIEAYILGTGCCPFLTR", "length": 343, "header": "tr|A0A452DJG3-1|TM268_BOVIN Computationally mapped isoform of Transmembrane protein 268 OS=Bos taurus OX=9913 GN=TMEM268 PE=2 SV=1 CANONICAL=Q5EA48-1" }, "locus": { "chromosome": "8", "start_pos": 103824339, "end_pos": 103803980, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000055284.5", "url": "https://www.ensembl.org/id/ENSBTAT00000055284.5" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000048776.3", "url": "https://www.ensembl.org/id/ENSBTAP00000048776.3" } ] } }, { "isoform_ac": "Q5EA48-1", "url": "https://www.uniprot.org/uniprotkb/Q5EA48/entry#Q5EA48-1", "sequence": { "sequence": "MACEPQMDPGGAAGPLPTSSPGWSPLPGGSPPGWGQELRSGQVLTVLRIDNTCAPISFDLGAAEEQLQTWGIQVPADQYRSLAESALLEPQVRRYIIYNSRPMRLAFAVVFYVVVWANIYSTSQMFALGNHWAGVLLVTLAATSLTLTLVVIFERHQRKANTNTDLRLTAANGALLRHRVLLGVTDTVEGCQSVIQLWFVYFDLETCAQFLSDHIREMKMSQESLLRSRLSQLCVVMETGVSPTANEGPENLLEETPLLPDRPGSTEKPLMQTELRQLVPEAEPEEMAQQLLAVFGGYYTRLLVTSQLPQALGTRHMDSPRIPCPCQLIEAYILGTECCPFLTR", "length": 344, "header": "sp|Q5EA48-1|TM268_BOVIN Isoform 1 of Transmembrane protein 268 OS=Bos taurus OX=9913 GN=TMEM268 PE=2 SV=1 CANONICAL=Q5EA48-1" }, "locus": {} } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [ { "title": "Characterization of 954 bovine full-CDS cDNA sequences.", "journal": "BMC Genomics", "date": "2005", "authors": "Harhay Gregory P, Sonstegard Tad S, Keele John W, Heaton Michael P, Clawson Michael L, Snelling Warren M, Wiedmann Ralph T, Van Tassell Curt P, Smith Timothy P L", "evidence": [ { "database": "UniProtKB", "id": "Q5EA48", "url": "https://www.uniprot.org/uniprotkb/Q5EA48" } ], "reference": [ { "type": "PubMed", "id": "16305752", "url": "https://glygen.org/publication/PubMed/16305752" } ] } ], "pathway": [ { "id": "bta:535122", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?bta:535122", "resource": "KEGG Pathway" } ], "orthologs": [ { "uniprot_canonical_ac": "D3ZSU8-1", "protein_name": 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"MACEPPTDPGGAAGPLPTSTLGCNILPQGNPPGWGQELHNGQVLTVLRIDNTCAPISFDLGAAEEQLQAWGIQVPAEQYRNLAESALLEPQVRRYIIYNSRPMRLAFAVVFYVLVWANIYSTSQMFALGNQWAGVLLATLAAFSLTLTLVLVFERQQRKANTNTDLRLVAANGALLRHRVLLGVTDTVEGCQSVIQLWFVYFDLENCVQFLSDHVQEMKRSQESLLRSRLSQLCVVMETGVSPVVEGPEDLEDAPLLPSTPGPQERPLTQTELYQLVPEAEPEEMARQLLAVFGGYYTRLLVTSRLPQSMGTRHMDSARIPCPCQLIEVHVLGTGCCPFLAR", "length": 342 }, "evidence": [ { "id": "Q5EA48", "url": "https://omabrowser.org/oma/group/Q5EA48/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" } ], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 1, "go_terms": [ { "name": "plasma membrane", "id": "GO:0005886", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005886", "evidence": [ { "database": "UniProtKB", "id": "Q5EA48", "url": "https://www.uniprot.org/uniprotkb/Q5EA48" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], 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"https://alphafold.ebi.ac.uk/entry/Q32KU3", "database": "AlphaFoldDB", "categories": [] }, { "id": "ENSBTAG00000024042", "url": "https://bgee.org/?page=gene&gene_id=ENSBTAG00000024042", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "616607", "url": "https://www.ncbi.nlm.nih.gov/gene/616607", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR003409", "url": "https://www.ebi.ac.uk/interpro/entry/IPR003409", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR052849", "url": "https://www.ebi.ac.uk/interpro/entry/IPR052849", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "bta:616607", "url": "https://www.genome.jp/dbget-bin/www_bget?bta:616607", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "A0A452DK10", "url": "https://www.orthodb.org/?gene=A0A452DK10", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "Q32KU3", "url": "https://www.orthodb.org/?gene=Q32KU3", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR46917", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR46917", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR46917:SF1", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR46917:SF1", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF02493", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF02493", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "NP_001069896", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001069896", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A452DK10", "url": "https://www.uniprot.org/uniprotkb/A0A452DK10", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A452DK10-1", "url": "https://www.uniprot.org/uniprotkb/A0A452DK10-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0AAA9SPM9", "url": "https://www.uniprot.org/uniprotkb/A0AAA9SPM9", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0AAA9SPM9-1", "url": "https://www.uniprot.org/uniprotkb/A0AAA9SPM9-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "Q32KU3", "url": "https://www.uniprot.org/uniprotkb/Q32KU3", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "Q32KU3-1", "url": "https://www.uniprot.org/uniprotkb/Q32KU3-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MNGFGRLEHFSGAIYEGHFKDNMFHGLGTYTFPNGAKYTGNFNENRVEGEGQYTDIQGLEWCGNFHFTAAPGLRLKLHM", "length": 79, "header": "sp|Q32KU3-1|MORN2_BOVIN Isoform 1 of MORN repeat-containing protein 2 OS=Bos taurus OX=9913 GN=MORN2 PE=4 SV=1 CANONICAL=Q32KU3-1" }, "isoforms": [ { "isoform_ac": "A0A452DK10-1", "url": "https://www.uniprot.org/uniprotkb/A0A452DK10/entry", "sequence": { "sequence": "MAAQGESQSPENLSRSPVSTPEVFKINFIFPNGDKYDGDCIRTSSGVIERNGIGIHTTPNGIVYTGSWKDDKMNGFGRLEHFSGAIYEGHFKDNMFHGLGTYTFPNGAKYTGNFNENRVEGEGQYTDIQGLEWCGNFHFTAAPGLRLKLHM", "length": 151, "header": "tr|A0A452DK10-1|MORN2_BOVIN Computationally mapped isoform of MORN repeat-containing protein 2 OS=Bos taurus OX=9913 GN=MORN2 PE=4 SV=3 CANONICAL=Q32KU3-1" }, "locus": { "chromosome": "11", "start_pos": 21213774, "end_pos": 21205758, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000033131.5", "url": "https://www.ensembl.org/id/ENSBTAT00000033131.5" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000033055.5", "url": "https://www.ensembl.org/id/ENSBTAP00000033055.5" } ] } }, { "isoform_ac": "A0AAA9SPM9-1", "url": "https://www.uniprot.org/uniprotkb/A0AAA9SPM9/entry", "sequence": { "sequence": "MGLSTQEAGKMTRVEGEGQYTDIQGLEWCGNFHFTAAPGLRLKLHM", "length": 46, "header": "tr|A0AAA9SPM9-1|MORN2_BOVIN Computationally mapped isoform of MORN repeat-containing protein 2 OS=Bos taurus OX=9913 GN=MORN2 PE=4 SV=1 CANONICAL=Q32KU3-1" }, "locus": { "chromosome": "11", "start_pos": 21213774, "end_pos": 21210832, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000097957.2", "url": "https://www.ensembl.org/id/ENSBTAT00000097957.2" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000088248.1", "url": "https://www.ensembl.org/id/ENSBTAP00000088248.1" } ] } }, { "isoform_ac": "Q32KU3-1", "url": "https://www.uniprot.org/uniprotkb/Q32KU3/entry#Q32KU3-1", "sequence": { "sequence": "MNGFGRLEHFSGAIYEGHFKDNMFHGLGTYTFPNGAKYTGNFNENRVEGEGQYTDIQGLEWCGNFHFTAAPGLRLKLHM", "length": 79, "header": "sp|Q32KU3-1|MORN2_BOVIN Isoform 1 of MORN repeat-containing protein 2 OS=Bos taurus OX=9913 GN=MORN2 PE=4 SV=1 CANONICAL=Q32KU3-1" }, "locus": {} } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [ { "id": "bta:616607", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?bta:616607", "resource": "KEGG Pathway" } ], "orthologs": [], "go_annotation": {}, "pro_annotation": [], "site_annotation": [], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [ { "pdb_id": "AF-Q32KU3-F1", "pdb_chain": "global", "start_pos": 1, "end_pos": 79, "overlap": "1.0", "method": "AlphaFold", "type": "alphafold", "resolution": -1.0, "url": "https://data.glygen.org/ln2downloads/pdb/current/AF-Q32KU3-F1.pdb", "url_external": "https://alphafold.ebi.ac.uk/entry/Q32KU3" } ], "lectin_list": [], "domain_list": [], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", 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"tool_support": { "graph_view": "yes" } }, { "uniprot_canonical_ac": "Q3ZC52-1", "uniprot_ac": "Q3ZC52", "uniprot_id": "TEX30_BOVIN", "mass": { "chemical_mass": 25181.0, "monoisotopic_mass": 25181.0 }, "refseq": { "ac": "NP_001069763", "name": "testis-expressed protein 30", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001069763" }, "gene_names": [ { "name": "TEX30", "type": "recommended", "evidence": [ { "id": "Q3ZC52", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q3ZC52" } ] }, { "name": "C12H13orf27", "type": "synonym", "evidence": [ { "id": "NP_001069763", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001069763" } ] }, { "name": "C13orf27", "type": "synonym", "evidence": [ { "id": "NP_001069763", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001069763" } ] }, { "name": "TEX30", "type": "synonym", "evidence": [ { "id": "NP_001069763", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001069763" } ] } ], "protein_names": [ { "name": "Testis-expressed protein 30", "type": "recommended", "evidence": [ { "id": "Q3ZC52", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q3ZC52/entry#names_and_taxonomy" } ] }, { "name": "testis-expressed protein 30", "type": "synonym", "evidence": [ { "id": "NP_001069763", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001069763" } ] }, { "name": "testis-expressed sequence 30 protein", "type": "synonym", "evidence": [ { "id": "NP_001069763", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001069763" } ] }, { "name": "uncharacterized protein C13orf27 homolog", "type": "synonym", "evidence": [ { "id": "NP_001069763", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001069763" } ] } ], "function": [], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Bos taurus", "taxid": 9913, "evidence": [ { "database": "UniProtKB", "id": "Q3ZC52", "url": "https://www.uniprot.org/uniprotkb/Q3ZC52" } ], "common_name": "Bovine", "glygen_name": "Bovine", "reference_species": "Bos taurus [9913]" } ], "gene": [ { "name": "TEX30", "url": "https://www.uniprot.org/uniprotkb/Q3ZC52", "locus": { "chromosome": "12", "start_pos": 79008354, "end_pos": 79015048, "strand": "+", "evidence": [ { "database": "Ensembl Gene", "id": "ENSBTAG00000025221", "url": "https://www.ensembl.org/id/ENSBTAG00000025221" } ] } } ], "crossref": [ { "id": "Q3ZC52", "url": "https://alphafold.ebi.ac.uk/entry/Q3ZC52", "database": "AlphaFoldDB", "categories": [] }, { "id": "ENSBTAG00000025221", "url": "https://bgee.org/?page=gene&gene_id=ENSBTAG00000025221", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "613895", "url": "https://www.ncbi.nlm.nih.gov/gene/613895", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR026555", "url": "https://www.ebi.ac.uk/interpro/entry/IPR026555", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR029058", "url": "https://www.ebi.ac.uk/interpro/entry/IPR029058", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR046879", "url": "https://www.ebi.ac.uk/interpro/entry/IPR046879", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "bta:613895", "url": "https://www.genome.jp/dbget-bin/www_bget?bta:613895", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "EVFWLQG", "url": "https://omabrowser.org/oma/group/EVFWLQG/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "Q3ZC52", "url": "https://www.orthodb.org/?gene=Q3ZC52", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR13136", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR13136", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR13136:SF11", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR13136:SF11", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF20408", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF20408", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "NP_001069763", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001069763", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0AAA9RTS0", "url": "https://www.uniprot.org/uniprotkb/A0AAA9RTS0", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0AAA9RTS0-1", "url": "https://www.uniprot.org/uniprotkb/A0AAA9RTS0-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0AAA9SZH6", "url": "https://www.uniprot.org/uniprotkb/A0AAA9SZH6", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0AAA9SZH6-1", "url": "https://www.uniprot.org/uniprotkb/A0AAA9SZH6-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0AAA9TIV4", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TIV4", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0AAA9TIV4-1", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TIV4-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "Q3ZC52", "url": "https://www.uniprot.org/uniprotkb/Q3ZC52", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "Q3ZC52-1", "url": "https://www.uniprot.org/uniprotkb/Q3ZC52-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MSHTEVKLKVPFGNKLLDAVCLVPNKSLTYGVILTHGASGDMNLPHLTSLASHLASHGFFCLRFTCKGLNIVHRIKAYKSVLNYLKTSEYKLAGVFLGGRSMGSRAAASVLCHIEPDDADDFVRGLICISYPLHHPKQQHKLRDEDLFRIKDPVLFVSGSADEMCEKNLLEKVAQKMQAPHKIHWIEKANHSMAVKGRSTNDVFKEINTQILFWIQEITETDKK", "length": 224, "header": "sp|Q3ZC52-1|TEX30_BOVIN Isoform 1 of Testis-expressed protein 30 OS=Bos taurus OX=9913 GN=TEX30 PE=2 SV=2 CANONICAL=Q3ZC52-1" }, "isoforms": [ { "isoform_ac": "A0AAA9RTS0-1", "url": "https://www.uniprot.org/uniprotkb/A0AAA9RTS0/entry", "sequence": { "sequence": "MSHTEVKLKVPFGNKLLDAVCLVPNKSLTYGVILTHGASGDMNLPHLTSLASHLASHGFFCLRFTCKGLNIVHRIKAYKSVLNYLKTSEYKLAGVFLGELVGESGTENASSS", "length": 112, "header": "tr|A0AAA9RTS0-1|TEX30_BOVIN Computationally mapped isoform of Testis-expressed protein 30 OS=Bos taurus OX=9913 GN=TEX30 PE=2 SV=1 CANONICAL=Q3ZC52-1" }, "locus": { "chromosome": "12", "start_pos": 79011721, "end_pos": 79008778, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000123491.1", "url": "https://www.ensembl.org/id/ENSBTAT00000123491.1" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000075377.1", "url": "https://www.ensembl.org/id/ENSBTAP00000075377.1" } ] } }, { "isoform_ac": "A0AAA9SZH6-1", "url": "https://www.uniprot.org/uniprotkb/A0AAA9SZH6/entry", "sequence": { "sequence": "MLIGLGWTPDFSFEFRSAPCIFIVEPGLKRQKYVERTFLGAEGRCPLLLRCKALKDCYSTVKMSHTEVKLKVPFGNKLLDAVCLVPNKSLTYGVILTHGASGDMNLPHLTSLASHLASHGFFCLRFTCKGLNIVHRIKAYKSVLNYLKTSEYKLAGVFLGGRSMGSRAAASVLCHIEPDDADDFVRGLICISYPLHHPKQQHKLRDEDLFRIKDPVLFVSGSADEMCEKNLLEKVAQKMQAPHKIHWIEKANHSMAVKGRSTNDVFKEINTQILFWIQEITETDKK", "length": 286, "header": "tr|A0AAA9SZH6-1|TEX30_BOVIN Computationally mapped isoform of Testis-expressed protein 30 OS=Bos taurus OX=9913 GN=TEX30 PE=2 SV=1 CANONICAL=Q3ZC52-1" }, "locus": { "chromosome": "12", "start_pos": 79012500, "end_pos": 79008648, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000091690.1", "url": "https://www.ensembl.org/id/ENSBTAT00000091690.1" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000088778.1", "url": "https://www.ensembl.org/id/ENSBTAP00000088778.1" } ] } }, { "isoform_ac": "A0AAA9TIV4-1", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TIV4/entry", "sequence": { "sequence": "MLIGLGWTPDFSFEFRSAPCIFIVEPGLKRQKYVERTFLGAEGRCPLLLRCKALKDCYSTVKMSHTENYLKTSEYKLAGVFLGGRSMGSRAAASVLCHIEPDDADDFVRGLICISYPLHHPKQQHKLRDEDLFRIKDPVLFVSGSADEMCEKNLLEKVAQKMQAPHKIHWIEKANHSMAVKGRSTNDVFKEINTQILFWIQEITETDKK", "length": 209, "header": "tr|A0AAA9TIV4-1|TEX30_BOVIN Computationally mapped isoform of Testis-expressed protein 30 OS=Bos taurus OX=9913 GN=TEX30 PE=2 SV=1 CANONICAL=Q3ZC52-1" }, "locus": { "chromosome": "12", "start_pos": 79012500, "end_pos": 79008648, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000118049.1", "url": "https://www.ensembl.org/id/ENSBTAT00000118049.1" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000098254.1", "url": "https://www.ensembl.org/id/ENSBTAP00000098254.1" } ] } }, { "isoform_ac": "Q3ZC52-1", "url": "https://www.uniprot.org/uniprotkb/Q3ZC52/entry#Q3ZC52-1", "sequence": { "sequence": "MSHTEVKLKVPFGNKLLDAVCLVPNKSLTYGVILTHGASGDMNLPHLTSLASHLASHGFFCLRFTCKGLNIVHRIKAYKSVLNYLKTSEYKLAGVFLGGRSMGSRAAASVLCHIEPDDADDFVRGLICISYPLHHPKQQHKLRDEDLFRIKDPVLFVSGSADEMCEKNLLEKVAQKMQAPHKIHWIEKANHSMAVKGRSTNDVFKEINTQILFWIQEITETDKK", "length": 224, "header": "sp|Q3ZC52-1|TEX30_BOVIN Isoform 1 of Testis-expressed protein 30 OS=Bos taurus OX=9913 GN=TEX30 PE=2 SV=2 CANONICAL=Q3ZC52-1" }, "locus": { "chromosome": "12", "start_pos": 79011721, "end_pos": 79008648, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000035359.6", "url": "https://www.ensembl.org/id/ENSBTAT00000035359.6" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000035234.4", "url": "https://www.ensembl.org/id/ENSBTAP00000035234.4" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [ { "id": "bta:613895", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?bta:613895", "resource": "KEGG Pathway" } ], "orthologs": [ { "uniprot_canonical_ac": "A0A4X1UA98-1", "protein_name": "Testis expressed 30", "gene_name": "TEX30", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MSHTEVKLKIPFGNKLLDAVCLVPNKSLTYGIILTHGASGDMNLPHLMSLASHLASHGFFCLRFTCKGLNIVHRIKAYKSVLNYLKTSGEYKLAGVFLGGRSMGSRAAASVMCHIEPDDADDFVRGLICISYPLHHPKQQHKLRDEDLFRIKDPVLFVSGSADEMCEKNLLEKVAQKMQAPNKIHWIEKANHSMAVKGRSTNDVFKEINTQILFWIQEITEMVKK", "length": 225 }, "evidence": [ { "id": "Q3ZC52", "url": "https://omabrowser.org/oma/group/Q3ZC52/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "G3IDW2-1", "protein_name": "Testis-expressed protein 30", "gene_name": "Tex30", "tax_id": 10029, "organism": "Cricetulus griseus", "sequence": { "sequence": "MSHTEVKLKIPFGNKLLDAVCLVPNKNIAYGIILTHGASGDMNLPHLMSLASHLASHGFFCLRFTCKGLNIVHRIKAYKAVLNYLKTSGEYKLAGVFLGGRSMGSRAAASVMCHTEPDDTDDFVRGLICISYPLHHPKQQQKLRDEDLFRIKDPVLFVSGSADEMCEKNLLEKVAQKMQAPSKIHWIEKANHSMAVKGRSTNDVFKEINTQILFWIQEITEMDKK", "length": 225 }, "evidence": [ { "id": "Q3ZC52", "url": "https://omabrowser.org/oma/group/Q3ZC52/", "database": "OMA" } ], "glygen_name": "Hamster", "common_name": "Chinese hamster" }, { "uniprot_canonical_ac": "Q3TUU5-1", "protein_name": "Testis-expressed protein 30", "gene_name": "Tex30", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MSHTEVKLKIPFGNKLLDAVCLVPNKNIAYGIILTHGASGDMNLPHLMSLASHLASHGFFCLRFTCKGLNIVHRIKAYKAVLNYLKTSGEYKLAGVFLGGRSMGSRAAASVMCHTEPDDADDFVRGLICISYPLHHPKQQHKLRDEDLFRIKDPVLFVSGSADEMCEKNLLEKVAQKMQAPSKIHWIEKANHSMAVKGRSTNDVFKEINTQILFWIQEITEMDKK", "length": 225 }, "evidence": [ { "id": "Q3ZC52", "url": "https://omabrowser.org/oma/group/Q3ZC52/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q5JUR7-1", "protein_name": "Testis-expressed protein 30", "gene_name": "TEX30", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MSHTEVKLKIPFGNKLLDAVCLVPNKSLTYGIILTHGASGDMNLPHLMSLASHLASHGFFCLRFTCKGLNIVHRIKAYKSVLNYLKTSGEYKLAGVFLGGRSMGSRAAASVMCHIEPDDGDDFVRGLICISYPLHHPKQQHKLRDEDLFRLKEPVLFVSGSADEMCEKNLLEKVAQKMQAPHKIHWIEKANHSMAVKGRSTNDVFKEINTQILFWIQEITEMDKKCH", "length": 227 }, "evidence": [ { "id": "Q3ZC52", "url": "https://omabrowser.org/oma/group/Q3ZC52/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" } ], "go_annotation": {}, "pro_annotation": [], "site_annotation": [ { "start_pos": 190, "end_pos": 192, "annotation": "n_glycosylation_sequon" }, { "start_pos": 25, "end_pos": 27, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [ { "pdb_id": "AF-Q3ZC52-F1", "pdb_chain": "global", "start_pos": 1, "end_pos": 224, "overlap": "1.0", "method": "AlphaFold", "type": "alphafold", "resolution": -1.0, "url": "https://data.glygen.org/ln2downloads/pdb/current/AF-Q3ZC52-F1.pdb", "url_external": "https://alphafold.ebi.ac.uk/entry/Q3ZC52" } ], "lectin_list": [], "domain_list": [], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" }, { "name": "homologset.oma", "label": "OMA Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 190, "end_pos": 192 }, { "start_pos": 25, "end_pos": 27 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ], "tool_support": { "graph_view": "yes" } }, { "uniprot_canonical_ac": "Q0D2G3-1", "uniprot_ac": "Q0D2G3", "uniprot_id": "TM254_BOVIN", "mass": { "chemical_mass": 14724.0, "monoisotopic_mass": 14724.0 }, "refseq": { "ac": "NP_001068696", "name": "transmembrane protein 254", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001068696" }, "gene_names": [ { "name": "TMEM254", "type": "recommended", "evidence": [ { "id": "Q0D2G3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q0D2G3" } ] }, { "name": "C10orf57", "type": "synonym", "evidence": [ { "id": "NP_001068696", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001068696" } ] }, { "name": "C28H10orf57", "type": "synonym", "evidence": [ { "id": "NP_001068696", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001068696" } ] }, { "name": "TMEM254", "type": "synonym", "evidence": [ { "id": "NP_001068696", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001068696" } ] } ], "protein_names": [ { "name": "Transmembrane protein 254", "type": "recommended", "evidence": [ { "id": "Q0D2G3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q0D2G3/entry#names_and_taxonomy" } ] }, { "name": "transmembrane protein 254", "type": "synonym", "evidence": [ { "id": "NP_001068696", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001068696" } ] }, { "name": "transmembrane protein C10orf57 homolog", "type": "synonym", "evidence": [ { "id": "NP_001068696", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001068696" } ] } ], "function": [], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Bos taurus", "taxid": 9913, "evidence": [ { "database": "UniProtKB", "id": "Q0D2G3", "url": "https://www.uniprot.org/uniprotkb/Q0D2G3" } ], "common_name": "Bovine", "glygen_name": "Bovine", "reference_species": "Bos taurus [9913]" } ], "gene": [ { "name": "TMEM254", "url": "https://www.uniprot.org/uniprotkb/Q0D2G3", "locus": { "chromosome": "28", "start_pos": 35225744, "end_pos": 35234488, "strand": "+", "evidence": [ { "database": "Ensembl Gene", "id": "ENSBTAG00000001656", "url": "https://www.ensembl.org/id/ENSBTAG00000001656" } ] } } ], "crossref": [ { "id": "Q0D2G3", "url": "https://alphafold.ebi.ac.uk/entry/Q0D2G3", "database": "AlphaFoldDB", "categories": [] }, { "id": "ENSBTAG00000001656", "url": "https://bgee.org/?page=gene&gene_id=ENSBTAG00000001656", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "505854", "url": "https://www.ncbi.nlm.nih.gov/gene/505854", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR028110", "url": "https://www.ebi.ac.uk/interpro/entry/IPR028110", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "bta:505854", "url": "https://www.genome.jp/dbget-bin/www_bget?bta:505854", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "FHWFIQT", "url": "https://omabrowser.org/oma/group/FHWFIQT/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "Q0D2G3", "url": "https://www.orthodb.org/?gene=Q0D2G3", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR34104", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR34104", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR34104:SF3", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR34104:SF3", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF14934", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF14934", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "NP_001068696", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001068696", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0AAA9RUQ3", "url": "https://www.uniprot.org/uniprotkb/A0AAA9RUQ3", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0AAA9RUQ3-1", "url": "https://www.uniprot.org/uniprotkb/A0AAA9RUQ3-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "Q0D2G3", "url": "https://www.uniprot.org/uniprotkb/Q0D2G3", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "Q0D2G3-1", "url": "https://www.uniprot.org/uniprotkb/Q0D2G3-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MGKARGDEAYFQRSSLFWVTIIILSFGYYTWVIFWPESIPYQSLGPLGPFTQYLLKHHHTLVHAWYWLAWMIHVGESLYAIVLCKSKGITNTWTQLLWFLQTFLFGLASLYYLIAFRPKHQKQT", "length": 124, "header": "sp|Q0D2G3-1|TM254_BOVIN Isoform 1 of Transmembrane protein 254 OS=Bos taurus OX=9913 GN=TMEM254 PE=2 SV=1 CANONICAL=Q0D2G3-1" }, "isoforms": [ { "isoform_ac": "A0AAA9RUQ3-1", "url": "https://www.uniprot.org/uniprotkb/A0AAA9RUQ3/entry", "sequence": { "sequence": "MGKARGDEAYFQRSSLFWVTIIILSFGYYTWVIFWPESIPYQSLGPLGPFTQYLLKHHHTLVHAWYWLAWMIHVGESLYAIVLCK", "length": 85, "header": "tr|A0AAA9RUQ3-1|TM254_BOVIN Computationally mapped isoform of Transmembrane protein 254 OS=Bos taurus OX=9913 GN=TMEM254 PE=2 SV=1 CANONICAL=Q0D2G3-1" }, "locus": { "chromosome": "28", "start_pos": 35234470, "end_pos": 35228058, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000125797.1", "url": "https://www.ensembl.org/id/ENSBTAT00000125797.1" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000076965.1", "url": "https://www.ensembl.org/id/ENSBTAP00000076965.1" } ] } }, { "isoform_ac": "Q0D2G3-1", "url": "https://www.uniprot.org/uniprotkb/Q0D2G3/entry#Q0D2G3-1", "sequence": { "sequence": "MGKARGDEAYFQRSSLFWVTIIILSFGYYTWVIFWPESIPYQSLGPLGPFTQYLLKHHHTLVHAWYWLAWMIHVGESLYAIVLCKSKGITNTWTQLLWFLQTFLFGLASLYYLIAFRPKHQKQT", "length": 124, "header": "sp|Q0D2G3-1|TM254_BOVIN Isoform 1 of Transmembrane protein 254 OS=Bos taurus OX=9913 GN=TMEM254 PE=2 SV=1 CANONICAL=Q0D2G3-1" }, "locus": { "chromosome": "28", "start_pos": 35234470, "end_pos": 35227334, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000002166.6", "url": "https://www.ensembl.org/id/ENSBTAT00000002166.6" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000002166.5", "url": "https://www.ensembl.org/id/ENSBTAP00000002166.5" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [ { "id": "bta:505854", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?bta:505854", "resource": "KEGG Pathway" } ], "orthologs": [ { "uniprot_canonical_ac": "A0A8V0XZ29-1", "protein_name": "Transmembrane protein 254", "gene_name": "TMEM254", "tax_id": 9031, "organism": "Gallus gallus", "sequence": { "sequence": "MTGAERVRDGSCHFQRSRLIWMIGIILGMILLGWVTLSPSTIPYSYLGLFGDFLRYLVDNYHKWVCYGFYVSWLIHIVEALYGIKLCQSKGITDPAVQFHWFIQTLLFGSGTATSARGTSSEPFCNPNEDNEMSPICSQELFLRSSGSQLIFARKL", "length": 156 }, "evidence": [ { "id": "Q0D2G3", "url": "https://omabrowser.org/oma/group/Q0D2G3/", "database": "OMA" } ], "glygen_name": "Chicken", "common_name": "Chicken" } ], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 1, "go_terms": [ { "name": "membrane", "id": "GO:0016020", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016020", "evidence": [ { "database": "UniProtKB", "id": "Q0D2G3", "url": "https://www.uniprot.org/uniprotkb/Q0D2G3" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [ { "pdb_id": "AF-Q0D2G3-F1", "pdb_chain": "global", "start_pos": 1, "end_pos": 124, "overlap": "1.0", "method": "AlphaFold", "type": "alphafold", "resolution": -1.0, "url": "https://data.glygen.org/ln2downloads/pdb/current/AF-Q0D2G3-F1.pdb", "url_external": "https://alphafold.ebi.ac.uk/entry/Q0D2G3" } ], "lectin_list": [], "domain_list": [], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" }, { "name": "homologset.oma", "label": "OMA Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], 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"Protein" ] }, { "id": "A0AAA9RVU3-1", "url": "https://www.uniprot.org/uniprotkb/A0AAA9RVU3-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0AAA9SPB9", "url": "https://www.uniprot.org/uniprotkb/A0AAA9SPB9", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0AAA9SPB9-1", "url": "https://www.uniprot.org/uniprotkb/A0AAA9SPB9-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0ABI0P2Y4", "url": "https://www.uniprot.org/uniprotkb/A0ABI0P2Y4", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0ABI0P2Y4-1", "url": "https://www.uniprot.org/uniprotkb/A0ABI0P2Y4-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "Q17QZ7", "url": "https://www.uniprot.org/uniprotkb/Q17QZ7", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "Q17QZ7-1", "url": "https://www.uniprot.org/uniprotkb/Q17QZ7-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MSGVMWTPELAVLRGFPTQAERQQWKQEGVASLESGSFLQLLLEGNYKAILLNSLTQSILNSATITEEKIDSYLEKQIVTFLDDSAELDKIRRQQKILLLGVSSLQLFVQSNWTGPLVDLHPQDFLPSVLFQQFSEIKALDAFLLSLLVLDGESIYSLTTKPILLLLARIILVNIRHKLTAIQSLPWWTLRCVNIHQQLLEERSPQLFALAEDCIDQVMKLEDLFVDDSGQCLAVQFHLECAYIFLYYYEYKKAKDQFSIAKDICRLQIGLTGALGKRTRFQENYVAQLILDVRREGTVFSNCEFTPAPTPQEYLTKNLELNDDTVLNEIKLADCEQFQMPDLCAEELAVILGICTDFQKNNPVHKLTEEELLAFTSCLLSQPKFWAIQTSALILRTKLERGSTRRVERAMRQTQALADQFEDKTASVLERLKIFYCCQVPPHWAVQRQLAGLLFELGCTNSALQIFEKLEMWEDVVICYERAGQHGKAEEILRQELEKKETPSLYCLLGDVLRDHSYYDQAWELSRHRSARAQRSKGLLHLRSREFKECVECFERSLKINPMQLGVWFSLGCAYLALEDYGGSARAFQRCVTLEPDNAEAWNNLSTSYIRLKQKVKAFRTLQEALKCNYEHWQIWENYILTSTDVGEFSEAIKAYHRLLDLRDKYKDTQVLKILVRAVMDGMADRSGDVATGLRGKLQELFGRVTSRVTNDGEIWRLYAQVYGNGQSDKPDENEKAFQYLSKAYKCDTQSSCWEKNITSFKEVVQRALGLAHVAIKCSKNKSSPQEAIQVLSSVRLNLRGLLSKAKQLFTDAASGEIARELADEIAAMDTLVTELQDLSNQFRNQY", "length": 847, "header": "sp|Q17QZ7-1|TTC27_BOVIN Isoform 1 of Tetratricopeptide repeat protein 27 OS=Bos taurus OX=9913 GN=TTC27 PE=2 SV=1 CANONICAL=Q17QZ7-1" }, "isoforms": [ { "isoform_ac": "A0AAA9RVU3-1", "url": "https://www.uniprot.org/uniprotkb/A0AAA9RVU3/entry", "sequence": { "sequence": "MSGVMWTPELAVLRGFPTQAERQQWKQEGVASLESGSFLQLLLEGNYKAILLNSLTQSILNSATITEEKIDSYLEKQIVTFLDDSAELDKIRRQQKILLLGVSSLQLFVQSNWTGPLVDLHPQDFLPSVLFQQFSEIKALDAFLLSLLVLDGESIYSLTTKPILLLLARIILVNIRHKLTAIQSLPWWTLRCVNIHQQLLEERSPQLFALAEDCIDQVMKLEDLFVDDSGQCLAVQFHLECAYIFLYYYEYKKAKDQFSIAKDICRLQIGLTGALGKRTRFQENYVAQLILDVRREGTVFSNCEFTPAPTPQEYLTKNLELNDDTVLNEIKLADCEQFQMPDLCAEELAVILGICTDFQKNNPVHKLTEEELLAFTSCLLSQPKFWAIQTSALILRTKLERGSTRRVERAMRQTQALADQFEDKTASVLERLKIFYCCQVPPHWAVQRQLAGLLFELGCTNSALQIFEKLEMWEDVVICYERAGQHGKAEEILRQELEKKETPSLYCLLGDVLRDHSYYDQAWELSRHRSARAQRSKGLLHLRSREFKECVECFERSLKINPMQLGVWFSLGCAYLALEDYGGSARAFQRCVTLEPDNAEAWNNLSTSYIRLKQKVKAFRTLQEALKCNYEHWQIWENYILTSTDVGEFSEAIKAYHRLLDLRDKYKDTQVLKILVRAVMDGMADRSGDVATGLRGKLQELFGRVTSRVTNDGEIWRLYAQVYGNGQSDKPDENEKAFQYLSKAYKCDTQSSCWEKNITSFKEVVQRALGLAHATFYRCGKWRNCQGIS", "length": 789, "header": "tr|A0AAA9RVU3-1|TTC27_BOVIN Computationally mapped isoform of Tetratricopeptide repeat protein 27 OS=Bos taurus OX=9913 GN=TTC27 PE=2 SV=1 CANONICAL=Q17QZ7-1" }, "locus": { "chromosome": "11", "start_pos": 15362187, "end_pos": 15188656, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000046862.5", "url": "https://www.ensembl.org/id/ENSBTAT00000046862.5" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000044110.5", "url": "https://www.ensembl.org/id/ENSBTAP00000044110.5" } ] } }, { "isoform_ac": "A0AAA9SPB9-1", "url": "https://www.uniprot.org/uniprotkb/A0AAA9SPB9/entry", "sequence": { "sequence": "MLPKMEVLSPNLNHQGNTEESGSFLQLLLEGNYKAILLNSLTQSILNSATITEEKIDSYLEKQIVTFLDDSAELDKIRRQQKILLLGVSSLQLFVQSNWTGPLVDLHPQDFLPSVLFQQFSEIKALDAFLLSLLVLDGESIYSLTTKPILLLLARIILVNIRHKLTAIQSLPWWTLRCVNIHQQLLEERSPQLFALAEDCIDQVMKLEDLFVDDSGQCLAVQFHLECAYIFLYYYEYKKAKDQFSIAKDICRLQIGLTGALGKRTRFQENYVAQLILDVRREGTVFSNCEFTPAPTPQEYLTKNLELNDDTVLNEIKLADCEQFQMPDLCAEELAVILGICTDFQKNNPVHKLTEEELLAFTSCLLSQPKFWAIQTSALILRTKLERGSTRRVERAMRQTQALADQFEDKTASVLERLKIFYCCQVPPHWAVQRQLAGLLFELGCTNSALQIFEKLEMWEDVVICYERAGQHGKAEEILRQELEKKETPSLYCLLGDVLRDHSYYDQAWELSRHRSARAQRSKGLLHLRSREFKECVECFERSLKINPMQLGVWFSLGCAYLALEDYGGSARAFQRCVTLEPDNAEAWNNLSTSYIRLKQKVKAFRTLQEALKCNYEHWQIWENYILTSTDVGEFSEAIKAYHRLLDLRDKYKDTQVLKILVRAVMDGMADRSGDVATGLRGKLQELFGRVTSRVTNDGEIWRLYAQVYGNGQSDKPDENEKAFQYLSKAYKCDTQSSCWEKNITSFKEVVQRALGLAHVAIKCSKNKSSPQEAIQVLSSVRLNLRGLLSKAKQLFTDAASGEIARELADEIAAMDTLVTELQDLSNQFRNQY", "length": 833, "header": "tr|A0AAA9SPB9-1|TTC27_BOVIN Computationally mapped isoform of Tetratricopeptide repeat protein 27 OS=Bos taurus OX=9913 GN=TTC27 PE=2 SV=1 CANONICAL=Q17QZ7-1" }, "locus": { "chromosome": "11", "start_pos": 15362260, "end_pos": 15181286, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000119479.2", "url": "https://www.ensembl.org/id/ENSBTAT00000119479.2" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000085839.1", "url": "https://www.ensembl.org/id/ENSBTAP00000085839.1" } ] } }, { "isoform_ac": "A0ABI0P2Y4-1", "url": "https://www.uniprot.org/uniprotkb/A0ABI0P2Y4/entry", "sequence": { "sequence": "MSGVMWTPELAVLRGFPTQAERQQWKQEGVASLESGSFLQLLLEGNYKAILLNSLTQSILNSATITEEKIDSYLEKQIVTFLDDSAELDKIRRQQKILLLGVSSLQLFVQSNWTGPLVDLHPQDFLPSVLFQQFSESLPWWTLRCVNIHQQLLEERSPQLFALAEDCIDQVMKLEDLFVDDSGQCLAVQFHLECAYIFLYYYEYKKAKDQFSIAKDICRLQIGLTGALGKRTRFQENYVAQLILDVRREGTVFSNCEFTPAPTPQEYLTKNLELNDDTVLNEIKLADCEQFQMPDLCAEELAVILGICTDFQKNNPVHKLTEEELLAFTSCLLSQPKFWAIQTSALILRTKLERGSTRRVERAMRQTQALADQFEDKTASVLERLKIFYCCQVPPHWAVQRQLAGLLFELGCTNSALQIFEKLEMWEDVVICYERAGQHGKAEEILRQELEKKETPSLYCLLGDVLRDHSYYDQAWELSRHRSARAQRSKGLLHLRSREFKECVECFERSLKINPMQLGVWFSLGCAYLALEDYGGSARAFQRCVTLEPDNAEAWNNLSTSYIRLKQKVKAFRTLQEALKCNYEHWQIWENYILTSTDVGEFSEAIKAYHRLLDLRDKYKDTQVLKILVRAVMDGMADRSGDVATGLRGKLQELFGRVTSRVTNDGEIWRLYAQVYGNGQSDKPDENEKAFQYLSKAYKCDTQSSCWEKNITSFKEVVQRALGLAHVAIKCSKNKSSPQEAIQVLSSVRLNLRGLLSKAKQLFTDAASGEIARELADEIAAMDTLVTELQDLSNQFRNQY", "length": 800, "header": "tr|A0ABI0P2Y4-1|A0ABI0P2Y4_BOVIN Computationally mapped isoform of Tetratricopeptide repeat protein 27 OS=Bos taurus OX=9913 GN=TTC27 PE=3 SV=1 CANONICAL=Q17QZ7-1" }, "locus": { "chromosome": "11", "start_pos": 15362260, "end_pos": 15188656, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000142949.1", "url": "https://www.ensembl.org/id/ENSBTAT00000142949.1" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000107638.1", "url": "https://www.ensembl.org/id/ENSBTAP00000107638.1" } ] } }, { "isoform_ac": "Q17QZ7-1", "url": "https://www.uniprot.org/uniprotkb/Q17QZ7/entry#Q17QZ7-1", "sequence": { "sequence": "MSGVMWTPELAVLRGFPTQAERQQWKQEGVASLESGSFLQLLLEGNYKAILLNSLTQSILNSATITEEKIDSYLEKQIVTFLDDSAELDKIRRQQKILLLGVSSLQLFVQSNWTGPLVDLHPQDFLPSVLFQQFSEIKALDAFLLSLLVLDGESIYSLTTKPILLLLARIILVNIRHKLTAIQSLPWWTLRCVNIHQQLLEERSPQLFALAEDCIDQVMKLEDLFVDDSGQCLAVQFHLECAYIFLYYYEYKKAKDQFSIAKDICRLQIGLTGALGKRTRFQENYVAQLILDVRREGTVFSNCEFTPAPTPQEYLTKNLELNDDTVLNEIKLADCEQFQMPDLCAEELAVILGICTDFQKNNPVHKLTEEELLAFTSCLLSQPKFWAIQTSALILRTKLERGSTRRVERAMRQTQALADQFEDKTASVLERLKIFYCCQVPPHWAVQRQLAGLLFELGCTNSALQIFEKLEMWEDVVICYERAGQHGKAEEILRQELEKKETPSLYCLLGDVLRDHSYYDQAWELSRHRSARAQRSKGLLHLRSREFKECVECFERSLKINPMQLGVWFSLGCAYLALEDYGGSARAFQRCVTLEPDNAEAWNNLSTSYIRLKQKVKAFRTLQEALKCNYEHWQIWENYILTSTDVGEFSEAIKAYHRLLDLRDKYKDTQVLKILVRAVMDGMADRSGDVATGLRGKLQELFGRVTSRVTNDGEIWRLYAQVYGNGQSDKPDENEKAFQYLSKAYKCDTQSSCWEKNITSFKEVVQRALGLAHVAIKCSKNKSSPQEAIQVLSSVRLNLRGLLSKAKQLFTDAASGEIARELADEIAAMDTLVTELQDLSNQFRNQY", "length": 847, "header": "sp|Q17QZ7-1|TTC27_BOVIN Isoform 1 of Tetratricopeptide repeat protein 27 OS=Bos taurus OX=9913 GN=TTC27 PE=2 SV=1 CANONICAL=Q17QZ7-1" }, "locus": { "chromosome": "11", "start_pos": 15362260, "end_pos": 15188656, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000132331.2", "url": "https://www.ensembl.org/id/ENSBTAT00000132331.2" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000075217.2", "url": "https://www.ensembl.org/id/ENSBTAP00000075217.2" } ] } } ], "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "other", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 310, "start_aa": "Thr", "end_pos": 310, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr310", "evidence": [ { "id": "", "database": "GlyGen", "url": "https://data.glygen.org/" } ], "filter_code": "000000000000000010000.00000000001000.0.01000" } ], "phosphorylation": [], "glycation": [], "keywords": [ "glycoprotein", "glycoprotein_predicted" ], "publication": [], "pathway": [ { "id": "bta:524908", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?bta:524908", "resource": "KEGG Pathway" } ], "orthologs": [ { "uniprot_canonical_ac": "A0A8V0XVF5-1", "protein_name": "Tetratricopeptide repeat protein 27", "gene_name": "TTC27", "tax_id": 9031, "organism": "Gallus gallus", "sequence": { "sequence": "MLALERSLLRGFLSAAESQEWKQGEISATESGSVLQLIFDGKYEAIFSNSTIRNVFSASSVAEEDIESYLEKQILMYLDCSTEVDNMERQRLMFLLGVGSLQLFVQSNWTGPPVHLQLQDFLPSALLQKCLEPKMLHATILKMLVLDAESVYTLTSHPILLLIARVVLVNSRHKLSSLQTLPWWTLRCVNIHQQLLEERSPELFTLAQTCIRQMTEAEALFAGDEGWHLAVQFNLECAYTFLYYYEYKKAKQCFCTAKDIAKLQINLTGALGKRTRFQEKYVAQLILDVQRSEEFIPPHSELTPAPTPLENLTMNCDLNDDTVLNEIKLADADQYQVPDLCAEELAVILGICIDFQKNNPIHKLTEEELLAFTSCLLSQPKFWAIQTSALLLRTKLEKGSTRRMERAMKQTQALADQFEDVNTSVSERMKIFYCCQVPPHWAIQRQLASLLFELGCTSSALQIYEELEMWEDAVICYERAGQHGKAEEILRRELEKKETPVLYCLLGDVLKDHQCYDKAWELSRHRSARAQRSKGLLHLRNREFRECVECFERSVQINPMQLGVWFSLGCAYIALEGYEGAAKAFQRCVTLEPDNAEAWNNLSTAYIRLKQKIKAFRTLQEALKCNYEHWQIWENYLLTSTDVGEFSEAIKAYHRLMDLREKYKDTQVLAILVRAVVDGMADRTGEAASGLKGKLRELLGRVTSRVTNDGEIWRLYARLYGNGHSDSSEDIEKSLQCLTKAHKCEIQSNDWEKDVSSFKEVAKGAIEVAHVAIKCSKKKSNNQEALQILSSARLNLRGLSSKAKQRFVDVGSHEICNEVTDEVTTMDNLIAELQELSNQLRDQG", "length": 844 }, "evidence": [ { "id": "Q17QZ7", "url": "https://omabrowser.org/oma/group/Q17QZ7/", "database": "OMA" } ], "glygen_name": "Chicken", "common_name": "Chicken" }, { "uniprot_canonical_ac": "K7DY99-1", "protein_name": "Tetratricopeptide repeat protein 27", "gene_name": "ttc27", "tax_id": 7955, "organism": "Danio rerio", "sequence": { "sequence": "MLQLEAAVLGGLSLDWKQSSFSTADAGSLLQLVYDGDFEAVLFSSAVQGLLGVCPEEGDSIEAYLERQVLSYLSDATEEQRSHREVALLAVAVGCLNLFAQSNWTGPPVELHVSDVLPEALLQNFSQPAALSTALLSSLQLDGESVYSLVSNPLLLLLTRVIFVNCAAKLESLQLLPWWTLRYVALHQQILEERSPQLLNLMLSCIEKVCKCDELFSSNAHRNLAIQFHLECSYICLTYYEYHKAKEHLQTARDLSGLDVNMTGALGKRTRFQENFLAQLILDVKRKDNSPFYNSESPSSTPTPKELLPKDHQLSDDTVLNQINLAEPSEHELPDLSAEEQAFILATCTDFQKNNPVHKLNDEELLAFTTCLLSQPKFWAVEVTSLCLRTKLERGSSRRVERAMMQTQTLVDFFSEKDCPVTERLKMFYSCRAPPLWDLQRQLASLLTDLGLTSSALLIYERLELWEDAVVCLERMGQHGKAEEILRRELEKKETPSLYCLLGDVLKDPQYYDRAWELSKHRSARAQRSKALHHLRHREFQQCVECFERSLQINSMQLGVWFSLGCAYFALESYEGAARAFQRCVGLEPDNSEAWNNLSTAYIKLRVKEKAFRTLQEALKCNYERWQIWENFIAVCVDLGEFSEAIRAYHRLMELKDKYKDVEVLEILVQAVVDNLTDHRGEQASILRPKLQELLGRVSSRCSTDAQIWKQYARLYGDGHSNNAEDNEKALQFLSKAHRCETQAAGWEKDTGSFKSVVKGARDMANVSISCSRSKRSPQEALQLLSSARLSLKSLTTKARQLYTDVATGELHDDLRDDVIELEQLITEIQDLSAQLRSQ", "length": 839 }, "evidence": [ { "id": "Q17QZ7", "url": "https://omabrowser.org/oma/group/Q17QZ7/", "database": "OMA" } ], "glygen_name": "Zebrafish", "common_name": "Zebrafish" }, { "uniprot_canonical_ac": "Q00918-1", "protein_name": "Latent-transforming growth factor beta-binding protein 1", "gene_name": "Ltbp1", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MAGAWLRWGLLLWAGLLAWSAHGRVRRITYVVRPGPGLPAGTLPLAGPPRTFNVALDARYSRSSTATSSRSLAGPPAERTRRTSQPGGAALPGLRSPLPPEPARPGAPSRQLHSKAGAQTAVTRFAKHGRQVVRSKVQQDTQSSGGSRLQVQQKQQLQGINVCGGQCCHGWSKAPGSQRCTKPSCVPPCQNGGMCLRPQFCVCKPGTKGKACEITAAQDTMSPVFGGQNPGSSWVPPEPAAKRTSTKKADTLPRVSPVAQMTLTLKPKPSMGLSQQIHSQVAPLSSQNVMIRHGQTQEYVLKPKYFPAPKVVSGEQSTEGSFSLRYGQEQGTAPFQVSNHTGRIKVVFTPSICKVTCTKGNCHNSCQKGNTTTLISENGHAADTLTATNFRVVICHLPCMNGGQCSSRDKCQCPPNFTGKLCQIPVLGASMPKLYQHAQQPGKALGSHVIHSTHTLPLTMTNQQGVKVKFPPNIVNIHVKHPPEASVQIHQVSRIDGPVGQRVKEVQPGQSQVSYQGLPVQKTQTVHSTYSHQQVIPHVYPVAAKTQLGRCFQETIGSQCGKALPGLSKQEDCCGTVGTSWGFNKCQKCPKKQSYHGYTQMMECLQGYKRVNNTFCQDINECQLQGVCPNGECLNTMGSYRCSCKMGFGPDPTFSSCVPDPPMISEEKGPCYRLVSPGRQCMHPLSVHLTKQICCCSVGKAWGPQCEKCPLPGTAAFKEICPGGMGYTVSGIHRRRPIHQHIGKEAVFVKPKNTQPVAKSTHPPPLPAKEEPVEALTSSREHGPGVAEPEVVTAPPEKEIPSLDQEKTRLEPGQPQLSPGVSTIHLHPQFPVVVEKTSPPVPVEVAPEGSTSSASQVIAPTQVTEINECTVNPDICGAGHCINLPVRYTCICYEGYKFSEQQRKCIDIDECAQAQHLCSQGRCENTEGSFLCICPAGFIASEEGSNCIDVDECLRPDVCRDGRCINTAGAFRCEYCDSGYRMSRRGHCEDIDECLTPSTCPEEQCVNSPGSYQCVPCTEGFRGWNGQCLDVDECLQPKVCTNGSCTNLEGSYMCSCHKGYSPTPDHRHCQDIDECQQGNLCMNGQCKNTDGSFRCTCGQGYQLSAAKDQCEDIDECEHRHLCSHGQCRNTEGSFQCLCNQGYRASVLGDHCEDINECLEDSSVCQGGDCINTAGSYDCTCPDGLQLNDNKGCQDINECAQPGLCAPHGECLNTQGSFHCVCEQGFSISADGRTCEDIDECVNNTVCDSHGFCDNTAGSFRCLCYQGFQAPQDGQGCVDVNECELLSGVCGEAFCENVEGSFLCVCADENQEYSPMTGQCRSRATEDSGVDRQPKEEKKECYYNLNDASLCDNVLAPNVTKQECCCTSGAGWGDNCEIFPCPVQGTAEFSEMCPRGKGFVPAGESSYETGGENYKDADECLLFGEEICKNGYCLNTQPGYECYCKEGTYYDPVKLQCFDMDECQDPNSCIDGQCVNTEGSYNCFCTHPMVLDASEKRCVQPTESNEQIEETDVYQDLCWEHLSEEYVCSRPLVGKQTTYTECCCLYGEAWGMQCALCPMKDSDDYAQLCNIPVTGRRRPYGRDALVDFSEQYGPETDPYFIQDRFLNSFEELQAEECGILNGCENGRCVRVQEGYTCDCFDGYHLDMAKMTCVDVNECSELNNRMSLCKNAKCINTEGSYKCVCLPGYVPSDKPNYCTPLNTALNLDKDSDLE", "length": 1712 }, "evidence": [ { "id": "Q17QZ7", "url": "https://omabrowser.org/oma/group/Q17QZ7/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "Q6P3X3-1", "protein_name": "Tetratricopeptide repeat protein 27", "gene_name": "TTC27", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MWTPELAILRGFPTEAERQQWKQEGVVGSESGSFLQLLLEGNYEAIFLNSMTQNIFNSTTTAEEKIDSYLEKQVVTFLDYSTDLDTTERQQLIFLLGVSSLQLFVQSNWTGPPVDLHPQDFLSSVLFQQFSEVKGLDAFVLSLLTLDGESIYSLTSKPILLLLARIILVNVRHKLTAIQSLPWWTLRCVNIHQHLLEERSPLLFTLAENCIDQVMKLQNLFVDDSGRYLAIQFHLECAYVFLYYYEYRKAKDQLDIAKDISQLQIDLTGALGKRTRFQENYVAQLILDVRREGDVLSNCEFTPAPTPQEHLTKNLELNDDTILNDIKLADCEQFQMPDLCAEEIAIILGICTNFQKNNPVHTLTEVELLAFTSCLLSQPKFWAIQTSALILRTKLEKGSTRRVERAMRQTQALADQFEDKTTSVLERLKIFYCCQVPPHWAIQRQLASLLFELGCTSSALQIFEKLEMWEDVVICYERAGQHGKAEEILRQELEKKETPSLYCLLGDVLGDHSCYDKAWELSRYRSARAQRSKALLHLRNKEFQECVECFERSVKINPMQLGVWFSLGCAYLALEDYQGSAKAFQRCVTLEPDNAEAWNNLSTSYIRLKQKVKAFRTLQEALKCNYEHWQIWENYILTSTDVGEFSEAIKAYHRLLDLRDKYKDVQVLKILVRAVIDGMTDRSGDVATGLKGKLQELFGRVTSRVTNDGEIWRLYAHVYGNGQSEKPDENEKAFQCLSKAYKCDTQSNCWEKDITSFKEVVQRALGLAHVAIKCSKNKSSSQEAVQMLSSVRLNLRGLLSKAKQLFTDVATGEMSRELADDITAMDTLVTELQDLSNQFRNQY", "length": 843 }, "evidence": [ { "id": "Q17QZ7", "url": "https://omabrowser.org/oma/group/Q17QZ7/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "Q8CD92-1", "protein_name": "Tetratricopeptide repeat protein 27", "gene_name": "Ttc27", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MPGMMWTPELALLRGFSTEAERLVWKQEGICGSDIGVFLELLLEGSYEALFFHSTTQTILNSTMMAEEKIDSYLEKQIVNFLDCSTDLEEIERQQLVFLLGVSSLQLFVQSNWTGPLVDLHPQDFLPSGLLEQFSEVKGLDAIIMGLLILDGESVYSLTSKPILLLIARIILVNIRHKLTALQSLPWWTLRYVNIHQQLLEERSPQLFALAKNCIDQVMKQENLFEGDSGRLLAIQFHLECAHVFLYYYEYKEAKDQFSTAKDISKLEIDLTGALGKRTRFQENYVAQLIVDVRRKEAVPFSCEFSPAPTPQECLAKNLELNDDTVLNEIKLADSERFQMPDLCAEELAVVLGVCTNFQKNNPVHKLTEEELLAFTSCLLSQPKFWAIQMSALILRTKLERGSTRRVERAMRQTQALADQFEDKATSVLERLKIFYCCQVPPHWAVQRQLAGLLFELGCTSSALQIFEKLEMWEDVVICHERAGRHGKAEEILRQELEKKETPGLYCLLGDVLQDHSCYDKAWELSRHRSARAQRSKALLHLRNKEFRECVECFERSVKINPMQLGVWFSLGCAYLALEDYGGSAKAFQRCVTLEPDNAEAWNNLSTSYIRLKQKVKAFRTLQEALKCNYEHWQIWENYILTSTDVGEFGEAIKAYHRLLDLRDKYKDIQVLKILVQAVVNDMTDRSGAVASSLKGKLQELFGRITSRVTNDGEVWRLYAQVHGNGQSEKPDENDKAFQCLSKAYKCDTQSSCWEKDATAFKEVVQRAIGLAHVAMKCAESKSIPQEAVQTLSSVRLNLRGLLSKAKQNFTDVVSGEVSGELASEIAAVNALEAELQDLSNQLRNRY", "length": 847 }, "evidence": [ { "id": "Q17QZ7", "url": "https://omabrowser.org/oma/group/Q17QZ7/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q9FFI4-1", "protein_name": "Protein prenylyltransferase superfamily protein", "gene_name": "MKP11.12", "tax_id": 3702, "organism": "Arabidopsis thaliana", "sequence": { "sequence": "MVDGEVEILRGYELRLLRCTVSFPQTGSPLESQPLDGTQSGTHPHDSLITSLLSSIEAGDYLGALSSDATKLILGDSELNLVDTVDSAEQVYSELLDKVESFVVNDSSDEIDKARRAVLVMCLAIATALWFTRCNLTGSTEGSTKCSLPLRVSESKELVEWENWAKIQLMSVGSDLLGKFSNLQHLVFARLLLFKLKDLLFEITSTETFEVRSISWWLVRVLLIHQRVLQERSSSLFEMLQVYMAEAIDHFGELEKVKSYWGANLLEDEASSITSTIHLEACVLQYIYGRIDPSRLQLESAKAAASLEFSVTGALGFRTIHQVDPKAQMVLVANTSSSNGDVRLASEKADVGPYEAWGGEAPEVYMTPKLVNNESEAGKDSVPLKPVEQALILAQCLLIERGSRHDEMQRWDMAPYIEAIDSQKSTYFVLRCFCDLLRVRWESTRGRTKGRALEMMDKLVGAINKSDPGVSNRIPLCYAVHLPTIPALRKEYGELLVSCGLVGEAITIFESLELWDNLIYCYCLLGKKSAAVDLINARLLERPNDPRLWCSLGDVTINDSCYEKALEVSNDKSVRAKRALARSAYNRGDFEKSKMLWEAAMALNSLYPDGWFALGAAALKARDVQKALDAFTFAVQLDPDNGEAWNNIACLHMIKKKSKESFIAFKEALKFKRDSWQMWENFSHVAMDVGNIDQAFEAIQQILKMSKNKRVDVVLLDRIMTELEKRNSACKSSSSSTETEASSDESTETKPCTATPAETQRQLELLGKVIQQIVKTESTAEIWGLYARWSRIKGDLTVCSEALLKQVRSYQGSEVWKDKERFKKFARASLELCRVYMEISASIGSKRELFTAEMHLKNTIKQATVSFLDSEELKELESCLEEVRNVMQKSEEEYRDTKT", "length": 899 }, "evidence": [ { "id": "Q17QZ7", "url": "https://omabrowser.org/oma/group/Q17QZ7/", "database": "OMA" } ], "glygen_name": "Arabidopsis", "common_name": "Mouse-ear cress" }, { "uniprot_canonical_ac": "Q9VVM8-1", "protein_name": "Tetratricopeptide repeat protein 27", "gene_name": "Dmel\\CG5290", "tax_id": 7227, "organism": "Drosophila melanogaster", "sequence": { "sequence": "MVADIFSEYYICNFNDAVTVEDLPADETLRQLWTRQKLWTIDELREILQRWQEHVKPDPNDNPTSQLKDFLLLIFAFVQNSFTGPFDKLEEYQQIHSELELEKLDALEKLKASGEELNPNVKSVELLLIAREILEGLLENHPESKVLIWWRLRLICLHQHVLDDLAASLYEQFKSAAGHLQAHFNQFESRELQSLLLLELANGYLQFHRSEIASQILDELCKHLQVELKVEGLLGVRTKFQQKALPQLCLKVEHLNEQQPLPPAVQTNETTKLPKLLLLEDDTRLERIRFVELKDNEVMTLPSVLQALVLAKVKQLKRSTPKDRLADEQLEPYTQTLLYQEHGPFQVRQSALLLNCLQESNQRRTVERSWKQCEECVKLLDTSEEELSLRSRLSYGFAAHLSPKWQVQLQLVDLLRSLGMTKTALDICLRIHAWQQVIECYTSLELRHKAAEIIRQELEKKPTALLYCLLGDAIDDPSFYEQAWLYSKKTSGKAQAYWGNHFYRSADYAQAMDHFEISLEINNLQEAILLRCGYCAIQLERWEPAVKYYLAYTHLEPNGFESWNNLAKALIKLGDKQRAHRVLGEALKCNYSNWKVWENYMLVSVDTSHWDDAMRAYQRMAELKQHYLDQEVLTRIVYGVSKEDPAGSSALIKRLIKLLGQQSIQHGNEPLVWELAALVAQTPLKKAEKLVKSYRAYTPKHLGWETKSEHALKALDLCLEVCDLSVAAITEHIQEESEVMITSQLNSARLAGTSCLNALKRAINVDVSAEQTAKVEQLEKRIEDLTKIVQERMNASRS", "length": 798 }, "evidence": [ { "id": "Q17QZ7", "url": "https://omabrowser.org/oma/group/Q17QZ7/", "database": "OMA" } ], "glygen_name": "Fruit fly", "common_name": "Fruit fly" } ], 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"label": "Isoforms" }, { "name": "homologset.oma", "label": "OMA Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [ 310 ], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 112, "end_pos": 114 }, { "start_pos": 604, "end_pos": 606 }, { "start_pos": 757, "end_pos": 759 }, { "start_pos": 781, "end_pos": 783 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 1 }, { "field": "total_sites", "count": 1 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 1 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "exact_sites", "count": 1 }, { "field": "exact_o_linked_sites", "count": 1 }, { "field": "fuzzy_sites", "count": 0 } ], "sort_fields": [ 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"field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 1 }, { "field": "total_sites", "count": 1 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 1 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "exact_sites", "count": 1 }, { "field": "exact_o_linked_sites", "count": 1 }, { "field": "fuzzy_sites", "count": 0 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_pos", "start_aa", "end_pos", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", 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"graph_view": "yes" } }, { "uniprot_canonical_ac": "Q5EAD8-1", "uniprot_ac": "Q5EAD8", "uniprot_id": "LRC51_BOVIN", "mass": { "chemical_mass": 22107.0, "monoisotopic_mass": 22107.0 }, "refseq": { "ac": "NP_001019716", "name": "leucine-rich repeat-containing protein 51", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001019716" }, "gene_names": [ { "name": "LRRC51", "type": "recommended", "evidence": [ { "id": "Q5EAD8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q5EAD8" } ] }, { "name": "LRRC51", "type": "synonym", "evidence": [ { "id": "NP_001019716", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001019716" } ] } ], "protein_names": [ { "name": "Leucine-rich repeat-containing protein 51", "type": "recommended", "evidence": [ { "id": "Q5EAD8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q5EAD8/entry#names_and_taxonomy" } ] }, { "name": "leucine-rich repeat-containing protein 51", "type": "synonym", "evidence": [ { "id": "NP_001019716", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001019716" } ] } ], "function": [], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Bos taurus", "taxid": 9913, "evidence": [ { "database": "UniProtKB", "id": "Q5EAD8", "url": "https://www.uniprot.org/uniprotkb/Q5EAD8" } ], "common_name": "Bovine", "glygen_name": "Bovine", "reference_species": "Bos taurus [9913]" } ], "gene": [ { "name": "LRRC51", "url": "https://www.uniprot.org/uniprotkb/Q5EAD8", "locus": { "chromosome": "15", "start_pos": 51729483, "end_pos": 51714703, "strand": "-", "evidence": [ { "database": "Ensembl Gene", "id": "ENSBTAG00000017964", "url": "https://www.ensembl.org/id/ENSBTAG00000017964" } ] } } ], "crossref": [ { "id": "Q5EAD8", "url": "https://alphafold.ebi.ac.uk/entry/Q5EAD8", "database": "AlphaFoldDB", "categories": [] }, { "id": "ENSBTAG00000017964", "url": "https://bgee.org/?page=gene&gene_id=ENSBTAG00000017964", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "515066", "url": "https://www.ncbi.nlm.nih.gov/gene/515066", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "9FQR", "url": "https://www.ncbi.nlm.nih.gov/Structure/icn3d/?mmdbid=9FQR&bu=0", "database": "iCn3D", "categories": [ "3D Structure" ] }, { "id": "IPR001611", "url": "https://www.ebi.ac.uk/interpro/entry/IPR001611", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR032675", "url": "https://www.ebi.ac.uk/interpro/entry/IPR032675", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "bta:515066", "url": "https://www.genome.jp/dbget-bin/www_bget?bta:515066", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "LWHQSNS", "url": "https://omabrowser.org/oma/group/LWHQSNS/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "Q5EAD8", "url": "https://www.orthodb.org/?gene=Q5EAD8", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR46545", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR46545", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR46545:SF1", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR46545:SF1", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "pdb_00009fqr", "url": "https://www.rcsb.org/structure/pdb_00009fqr", "database": "PDB", "categories": [ "3D Structure" ] }, { "id": "9FQR", "url": "https://www.rcsb.org/structure/9FQR", "database": "PDB", "categories": [ "3D Structure" ] }, { "id": "PF14580", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF14580", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "NP_001019716", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001019716", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0AAA9RWX0", "url": "https://www.uniprot.org/uniprotkb/A0AAA9RWX0", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0AAA9RWX0-1", "url": "https://www.uniprot.org/uniprotkb/A0AAA9RWX0-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0AAA9TFX8", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TFX8", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0AAA9TFX8-1", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TFX8-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0AAF6Z4K8", "url": "https://www.uniprot.org/uniprotkb/A0AAF6Z4K8", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0AAF6Z4K8-1", "url": "https://www.uniprot.org/uniprotkb/A0AAF6Z4K8-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "Q5EAD8", "url": "https://www.uniprot.org/uniprotkb/Q5EAD8", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "Q5EAD8-1", "url": "https://www.uniprot.org/uniprotkb/Q5EAD8-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MNKRNYMNTSVQEPPLDYSFRSIHVTQDLLSEEPRTGLRPVRHAKSGKSMTQSLWLNNNVLTDLRDFNHAVSQLLEHPENLAWIDLSFNDLTSIDPVLTTFFNLSVLYLHGNSIQRLGEVNKLAALPRLRSLTLHGNPIEEEKGYRQYVLCTLPHITTFDFSGVTKADRTTAEVWKRMNIKPKKVRIKHNAL", "length": 192, "header": "sp|Q5EAD8-1|LRC51_BOVIN Isoform 1 of Leucine-rich repeat-containing protein 51 OS=Bos taurus OX=9913 GN=LRRC51 PE=1 SV=1 CANONICAL=Q5EAD8-1" }, "isoforms": [ { "isoform_ac": "A0AAA9RWX0-1", "url": "https://www.uniprot.org/uniprotkb/A0AAA9RWX0/entry", "sequence": { "sequence": "MNKRNYMNTSVQEPPLDYSFRSIHVTQAHSVPTDLLSEEPRTGLRPVRHAKSGKSMTQSLWLNNNVLTDLRDFNHAVSQLLEHPENLAWIDLSFNDLTSIDPVLTTFFNLSVLYLHGNSIQRLGEVNKLAALPRLRSLTLHGNPIEEEKGYRQYVLCTLPHITTFDFSGVTKADRTTAEVWKRMNIKPKKVRIKHNAL", "length": 198, "header": "tr|A0AAA9RWX0-1|LRC51_BOVIN Computationally mapped isoform of Leucine-rich repeat-containing protein 51 OS=Bos taurus OX=9913 GN=LRRC51 PE=1 SV=1 CANONICAL=Q5EAD8-1" }, "locus": { "chromosome": "15", "start_pos": 51728976, "end_pos": 51722857, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000128538.1", "url": "https://www.ensembl.org/id/ENSBTAT00000128538.1" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000077966.1", "url": "https://www.ensembl.org/id/ENSBTAP00000077966.1" } ] } }, { "isoform_ac": "A0AAA9TFX8-1", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TFX8/entry", "sequence": { "sequence": "MVEFQASVTDLLSEEPRTGLRPVRHAKSGKSMTQSLWLNNNVLTDLRDFNHAVSQLLEHPENLAWIDLSFNDLTSIDPVLTTFFNLSVLYLHGNSIQRLGEVNKLAALPRLRSLTLHGNPIEEEKGYRQYVLCTLPHITTFDFSGVTKADRTTAEVWKRMNIKPKKVRIKHNAL", "length": 174, "header": "tr|A0AAA9TFX8-1|LRC51_BOVIN Computationally mapped isoform of Leucine-rich repeat-containing protein 51 OS=Bos taurus OX=9913 GN=LRRC51 PE=1 SV=1 CANONICAL=Q5EAD8-1" }, "locus": { "chromosome": "15", "start_pos": 51728976, "end_pos": 51722178, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000118370.1", "url": "https://www.ensembl.org/id/ENSBTAT00000118370.1" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000097074.1", "url": "https://www.ensembl.org/id/ENSBTAP00000097074.1" } ] } }, { "isoform_ac": "A0AAF6Z4K8-1", "url": "https://www.uniprot.org/uniprotkb/A0AAF6Z4K8/entry", "sequence": { "sequence": "MFSSDHPGDLLSEEPRTGLRPVRHAKSGKSMTQSLWLNNNVLTDLRDFNHAVSQLLEHPENLAWIDLSFNDLTSIDPVLTTFFNLSVLYLHGNSIQRLGEVNKLAALPRLRSLTLHGNPIEEEKGYRQYVLCTLPHITTFDFSGVTKADRTTAEVWKRMNIKPKKVRIKHNAL", "length": 173, "header": "tr|A0AAF6Z4K8-1|A0AAF6Z4K8_BOVIN Computationally mapped isoform of Leucine-rich repeat-containing protein 51 OS=Bos taurus OX=9913 GN=LRRC51 PE=4 SV=1 CANONICAL=Q5EAD8-1" }, "locus": { "chromosome": "15", "start_pos": 51728976, "end_pos": 51724647, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000023886.4", "url": "https://www.ensembl.org/id/ENSBTAT00000023886.4" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000023886.3", "url": "https://www.ensembl.org/id/ENSBTAP00000023886.3" } ] } }, { "isoform_ac": "Q5EAD8-1", "url": "https://www.uniprot.org/uniprotkb/Q5EAD8/entry#Q5EAD8-1", "sequence": { "sequence": "MNKRNYMNTSVQEPPLDYSFRSIHVTQDLLSEEPRTGLRPVRHAKSGKSMTQSLWLNNNVLTDLRDFNHAVSQLLEHPENLAWIDLSFNDLTSIDPVLTTFFNLSVLYLHGNSIQRLGEVNKLAALPRLRSLTLHGNPIEEEKGYRQYVLCTLPHITTFDFSGVTKADRTTAEVWKRMNIKPKKVRIKHNAL", "length": 192, "header": "sp|Q5EAD8-1|LRC51_BOVIN Isoform 1 of Leucine-rich repeat-containing protein 51 OS=Bos taurus OX=9913 GN=LRRC51 PE=1 SV=1 CANONICAL=Q5EAD8-1" }, "locus": { "chromosome": "15", "start_pos": 51728976, "end_pos": 51722857, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000152034.1", "url": "https://www.ensembl.org/id/ENSBTAT00000152034.1" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000105014.1", "url": "https://www.ensembl.org/id/ENSBTAP00000105014.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [ { "title": "Characterization of 954 bovine full-CDS cDNA sequences.", "journal": "BMC Genomics", "date": "2005", "authors": "Harhay Gregory P, Sonstegard Tad S, Keele John W, Heaton Michael P, Clawson Michael L, Snelling Warren M, Wiedmann Ralph T, Van Tassell Curt P, Smith Timothy P L", "evidence": [ { "database": "UniProtKB", "id": "Q5EAD8", "url": "https://www.uniprot.org/uniprotkb/Q5EAD8" } ], "reference": [ { "type": "PubMed", "id": "16305752", "url": "https://glygen.org/publication/PubMed/16305752" } ] } ], "pathway": [ { "id": "bta:515066", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?bta:515066", "resource": "KEGG Pathway" } ], "orthologs": [ { "uniprot_canonical_ac": "A0A8V0XFN9-1", "protein_name": "Leucine-rich repeat-containing protein 51", "gene_name": "LOC107052453", "tax_id": 9031, "organism": "Gallus gallus", "sequence": { "sequence": "MGYGEGCGGGGGALLWGMGRAEGVCGVLCALGGGDRDCCGAAAGPGPIGCPTAMPSRPLPPELSPPLDFSFRPLRTLEDLSPEGGPSPTLALRLPYTGLSSLWGLHPTLQRLLADPTQLRWLDLSFNCLTAIDPVLTTLGGLQSLHLHGNAIGCLSEVDKLGALRQLHRLTLCGNPLEKERGYRRYVLALLPQLSTLDFSAVTQQEHREVAVWEHNQSRPRAQRASE", "length": 227 }, "evidence": [ { "id": "Q5EAD8", "url": "https://omabrowser.org/oma/group/Q5EAD8/", "database": "OMA" } ], "glygen_name": "Chicken", "common_name": "Chicken" }, { "uniprot_canonical_ac": "B6CZ61-1", "protein_name": "Leucine-rich repeat-containing protein 51", "gene_name": "Lrrc51", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MSKRDYMNTSVQEPPLDYSFKSVQMIQDLISEEPRTGLRPVKYSKSGKSLTQSLWLNNNVLNDLKDFNQVVSQLLQHPENLAWIDLSFNDLTTIDPVLTTFFNLSVLYLHGNSIHRLGEVNKLAVLPRLRSLTLHGNPIEEEKGYRQYVLCNLPRITTFDFSGVTKADRSTAEVWKRMNIKPKKVRIKQDVL", "length": 192 }, "evidence": [ { "id": "Q5EAD8", "url": "https://omabrowser.org/oma/group/Q5EAD8/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "G3II20-1", "protein_name": "Leucine-rich repeat-containing protein 51", "gene_name": "Lrrc51", "tax_id": 10029, "organism": "Cricetulus griseus", "sequence": { "sequence": "MSKRDYMNTSVQEPPLDYSFKSIHVVQDLVSEEPRTGLRPVKHTKSGKSMTQSLWLNNNVLNDLKDFSQVVSLLLQHPENLAWIDLSFNDLTSIDPVLTTFFNLSVLYLHGNSIHRLGEVNKLSVLPRLRSLTLHGNPIEEEKGYRQYVLCNLPRITTFDFSGITKADRTTAEVWKRMNIKPKKVRVKQDAL", "length": 192 }, "evidence": [ { "id": "Q5EAD8", "url": "https://omabrowser.org/oma/group/Q5EAD8/", "database": "OMA" } ], "glygen_name": "Hamster", "common_name": "Chinese hamster" }, { "uniprot_canonical_ac": "Q96E66-1", "protein_name": "Leucine-rich repeat-containing protein 51", "gene_name": "LRRC51", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MNKRDYMNTSVQEPPLDYSFRSIHVIQDLVNEEPRTGLRPLKRSKSGKSLTQSLWLNNNVLNDLRDFNQVASQLLEHPENLAWIDLSFNDLTSIDPVLTTFFNLSVLYLHGNSIQRLGEVNKLAVLPRLRSLTLHGNPMEEEKGYRQYVLCTLSRITTFDFSGVTKADRTTAEVWKRMNIKPKKAWTKQNTL", "length": 192 }, "evidence": [ { "id": "Q5EAD8", "url": "https://omabrowser.org/oma/group/Q5EAD8/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "Q9DAK8-1", "protein_name": "Leucine-rich repeat-containing protein 51", "gene_name": "Lrrc51", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MSSRDYMNTSVQEPPLDYSFKSVQMVQDLVTEEPRTGLRPVRHSKSGKSLTQSLWLNNNVLNDLKDFNQVVSQLLQHPENLAWIDLSFNDLTTIDPVLTTFFNLSVLYLHGNGIHRLGEVNKLAVLPRLRSLTLHGNPIEEEKGYRQYVLCNLPRITTFDFSGVTRADRSTAEVWKRMGIKPKKVRAKQDVL", "length": 192 }, "evidence": [ { "id": "Q5EAD8", "url": "https://omabrowser.org/oma/group/Q5EAD8/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" } ], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 2, "go_terms": [ { "name": "axoneme", "id": "GO:0005930", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005930", "evidence": [ { "database": "UniProtKB", "id": "Q5EAD8", "url": "https://www.uniprot.org/uniprotkb/Q5EAD8" } ], "pmid": "" }, { "name": "cytoplasm", "id": "GO:0005737", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005737", "evidence": [ { "database": "UniProtKB", "id": "Q5EAD8", "url": "https://www.uniprot.org/uniprotkb/Q5EAD8" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 103, "end_pos": 105, "annotation": "n_glycosylation_sequon" }, { "start_pos": 8, "end_pos": 10, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [ { "pdb_id": "AF-Q5EAD8-F1", "pdb_chain": "global", "start_pos": 1, "end_pos": 192, "overlap": "1.0", "method": "AlphaFold", "type": "alphafold", "resolution": -1.0, "url": "https://data.glygen.org/ln2downloads/pdb/current/AF-Q5EAD8-F1.pdb", "url_external": "https://alphafold.ebi.ac.uk/entry/Q5EAD8" } ], "lectin_list": [], "domain_list": [], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" }, { "name": "homologset.oma", "label": "OMA Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 103, "end_pos": 105 }, { "start_pos": 8, "end_pos": 10 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ], "tool_support": { "graph_view": "yes" } }, { "uniprot_canonical_ac": "Q2NL11-1", "uniprot_ac": "Q2NL11", "uniprot_id": "CH074_BOVIN", "mass": { "chemical_mass": 33972.0, "monoisotopic_mass": 33972.0 }, "refseq": { "ac": "NP_001070594", "name": "uncharacterized protein C8orf74 homolog", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001070594" }, "gene_names": [ { "name": "C8H8orf74", "type": "recommended", "evidence": [ { "id": "Q2NL11", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q2NL11" } ] }, { "name": "C8H8orf74", "type": "synonym", "evidence": [ { "id": "NP_001070594", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001070594" } ] }, { "name": "C8orf74", "type": "synonym", "evidence": [ { "id": "NP_001070594", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001070594" } ] } ], "protein_names": [ { "name": "Uncharacterized protein C8orf74 homolog", "type": "recommended", "evidence": [ { "id": "Q2NL11", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q2NL11/entry#names_and_taxonomy" } ] }, { "name": "uncharacterized protein C8orf74 homolog", "type": "synonym", "evidence": [ { "id": "NP_001070594", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001070594" } ] } ], "function": [], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Bos taurus", "taxid": 9913, "evidence": [ { "database": "UniProtKB", "id": "Q2NL11", "url": "https://www.uniprot.org/uniprotkb/Q2NL11" } ], "common_name": "Bovine", "glygen_name": "Bovine", "reference_species": "Bos taurus [9913]" } ], "gene": [ { "name": "", "url": "https://www.uniprot.org/uniprotkb/Q2NL11", "locus": {} } ], "crossref": [ { "id": "Q2NL11", "url": "https://alphafold.ebi.ac.uk/entry/Q2NL11", "database": "AlphaFoldDB", "categories": [] }, { "id": "ENSBTAG00000004134", "url": "https://bgee.org/?page=gene&gene_id=ENSBTAG00000004134", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "768069", "url": "https://www.ncbi.nlm.nih.gov/gene/768069", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR032727", "url": "https://www.ebi.ac.uk/interpro/entry/IPR032727", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "bta:768069", "url": "https://www.genome.jp/dbget-bin/www_bget?bta:768069", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "YQFVLCR", "url": "https://omabrowser.org/oma/group/YQFVLCR/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "Q2NL11", "url": "https://www.orthodb.org/?gene=Q2NL11", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR28457", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR28457", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR28457:SF2", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR28457:SF2", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF14769", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF14769", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "NP_001070594", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001070594", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0AAA9S2J3", "url": "https://www.uniprot.org/uniprotkb/A0AAA9S2J3", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0AAA9S2J3-1", "url": "https://www.uniprot.org/uniprotkb/A0AAA9S2J3-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "Q2NL11", "url": "https://www.uniprot.org/uniprotkb/Q2NL11", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "Q2NL11-1", "url": "https://www.uniprot.org/uniprotkb/Q2NL11-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MALLTAQGVKKVFQFQKPEGREHLRRLLNWEEFDELRDSRRSILLDTLYESIIFAVGKGFPWREVAQVVKFTEELLKETKGCSITEAVTILGNKLRDYQGQFNTTHLLALCDYFHNTFIRHYKLYQYVLGQDQDVNLTVTNLEVCTPPQPLPLAEGKDREVWKHEQQLEELSTAEVQKRTNMLLLKGALRLEQQHLLQETFSQLPGRRHQTLNREELEKLITEAIHIQIECLKELLQYEIQITFDILDLKLQKKTLNLNAPIPPLVPIAGQPGQDEALKLSKTHKGKKAKAKK", "length": 293, "header": "sp|Q2NL11-1|CH074_BOVIN Isoform 1 of Uncharacterized protein C8orf74 homolog OS=Bos taurus OX=9913 GN= PE=2 SV=1 CANONICAL=Q2NL11-1" }, "isoforms": [ { "isoform_ac": "A0AAA9S2J3-1", "url": "https://www.uniprot.org/uniprotkb/A0AAA9S2J3/entry", "sequence": { "sequence": "SPLLSPQGSNTLKPEGREHLRRLLNWEEFDELRDSRRSILLDTLYESIIFAVGKGFPWREVAQVVKFTEELLKETKGCSITEAVTILGNKLRDYQGQFNTTHLLALCDYFHNTFIRHYKLYQYVLGQDQDVNLTVTNLEVCTPPQPLPLAEGKDREVWKHEQQLEELSTAEVQKRTNMLLLKGALRLEQQHLLQETFSQLPGRRHQTLNREELEKLITEAIHIQIECLKELLQYEIQITFDILDLKLQKKTLNLNAPIPPLVPIAGQPGQDEALKLSKTHKGKKAKAKK", "length": 289, "header": "tr|A0AAA9S2J3-1|CH074_BOVIN Computationally mapped isoform of Uncharacterized protein C8orf74 homolog OS=Bos taurus OX=9913 GN= PE=2 SV=1 CANONICAL=Q2NL11-1" }, "locus": { "chromosome": "8", "start_pos": 8617724, "end_pos": 8587912, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000100430.1", "url": "https://www.ensembl.org/id/ENSBTAT00000100430.1" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000080132.1", "url": "https://www.ensembl.org/id/ENSBTAP00000080132.1" } ] } }, { "isoform_ac": "Q2NL11-1", "url": "https://www.uniprot.org/uniprotkb/Q2NL11/entry#Q2NL11-1", "sequence": { "sequence": "MALLTAQGVKKVFQFQKPEGREHLRRLLNWEEFDELRDSRRSILLDTLYESIIFAVGKGFPWREVAQVVKFTEELLKETKGCSITEAVTILGNKLRDYQGQFNTTHLLALCDYFHNTFIRHYKLYQYVLGQDQDVNLTVTNLEVCTPPQPLPLAEGKDREVWKHEQQLEELSTAEVQKRTNMLLLKGALRLEQQHLLQETFSQLPGRRHQTLNREELEKLITEAIHIQIECLKELLQYEIQITFDILDLKLQKKTLNLNAPIPPLVPIAGQPGQDEALKLSKTHKGKKAKAKK", "length": 293, "header": "sp|Q2NL11-1|CH074_BOVIN Isoform 1 of Uncharacterized protein C8orf74 homolog OS=Bos taurus OX=9913 GN= PE=2 SV=1 CANONICAL=Q2NL11-1" }, "locus": { "chromosome": "8", "start_pos": 8618646, "end_pos": 8587912, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000005411.6", "url": "https://www.ensembl.org/id/ENSBTAT00000005411.6" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000005411.5", "url": "https://www.ensembl.org/id/ENSBTAP00000005411.5" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [ { "id": "bta:768069", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?bta:768069", "resource": "KEGG Pathway" } ], "orthologs": [ { "uniprot_canonical_ac": "A0A8C2LEL4-1", "protein_name": "Uncharacterized protein C8orf74 homolog", "gene_name": "CUNH8orf74", "tax_id": 10029, "organism": "Cricetulus griseus", "sequence": { "sequence": "MALLTPQGVKEVFQFQKPQGREHLRRLLNWEEFDELRDARRSILLDTVYDSIIFAVGKGFPWVEVVQVVKFTEELLKETKGCSITEAVTVLGNKLRDYQKQFNVTHLLALCDYFHNTFIRHYRLYQYVLSQEQEVNLTVAHVQMCAPPQPLPLTEGMDRDVWRHEQQMAELSTAEVQKRTNVLLLKETLSLEQAHMLQKAFGGEEAPVQLQPRPTLRREALERLVSEAIHIQIACLQELLQYEIQAAFDILDLRLQKKTLSLGAPPPPLPCITSGQVAVEESPKASKSNKGKKGKAKK", "length": 298 }, "evidence": [ { "id": "Q2NL11", "url": "https://omabrowser.org/oma/group/Q2NL11/", "database": "OMA" } ], "glygen_name": "Hamster", "common_name": "Chinese hamster" }, { "uniprot_canonical_ac": "D3ZT70-1", "protein_name": "Similar to human chromosome 8 open reading frame 74", "gene_name": "C15h8orf74", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MALLTPQGVKEVFQFQKPQGRQHLRRLLNWEEFDELRDARRSILLDTLYDSVIFAVGKGFPWVEVVQVVKFTEELLRETKGCSITEAVTILGKKLQDYQKQFNVTHLLALCDYFHNTFIRHYRLYQYVLSQDQEVNLTVAHVQMCTPPQPLPLTDGKDRDVWKHEQQVAELSAAEAEKRSDVLVLKETLRMEQAQMLQKAFGVEEAPTQLQPRPTLRREALERLVSEAIHIQIACLQELLQYEIQAAFDILDLRLQKKTLSLSAPPPPLPCITAGPAALEDSPKASKANKGKKAKAKK", "length": 298 }, "evidence": [ { "id": "Q2NL11", "url": "https://omabrowser.org/oma/group/Q2NL11/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "Q6P047-1", "protein_name": "Uncharacterized protein C8orf74", "gene_name": "C8orf74", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MALLTPQGVKEVFQLQRPQGRERLRRLLNWEEFDEQRDSRRSILLDTLYESIIFAVGKGFPWVEVAQVVKFTEELLRETKGCSITEAVTILGNKLRDYRGHFNTTHLLALCDYFHHTFIRHYKLYQYVLGQDQQVDLTVAHLEVCMPPHPLPLAEGMDRDLWIHEQQVATLTEAEAQKRADVLLLKEALRLERENSLQKAFAAAAPAQPGQVLERQELESLICQAVHTQMELLQELLQRQIQNTFAILDLKLQKKTLNLNAPTPIPPPITSHAGQEEALKPQRASKGKKAKARK", "length": 294 }, "evidence": [ { "id": "Q2NL11", "url": "https://omabrowser.org/oma/group/Q2NL11/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "Q80ZQ3-1", "protein_name": "Uncharacterized protein C8orf74 homolog", "gene_name": "", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MALLTPQGVKEVFQFQKPQGRQHLRRLLNWEEFDELRDARQSILLDTLYDSVIFAVGKGFPWVEVVQVVKFTEELLKETKGCSITEAVTILGKKLRDYQKQFNVTHLLALCDYSHNTFIRHYRLYQYVLSQDQEVNLTVAHEQICAPPQPLPLTDGTDRDVWRHEQQVAELSTAEVEKRANVLMLKETLRMEQAQMLQKAFGVEEAPGQLQPHPTLRKEALERLVSEAIHIQIACLQELLQYEIQAAFDILDLRLQKKTLSLSAPPPPLPCITTGPAALEDSPKASKANKGKKAKAKK", "length": 298 }, "evidence": [ { "id": "Q2NL11", "url": "https://omabrowser.org/oma/group/Q2NL11/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" } ], "go_annotation": {}, "pro_annotation": [], "site_annotation": [ { "start_pos": 103, "end_pos": 105, "annotation": "n_glycosylation_sequon" }, { "start_pos": 136, "end_pos": 138, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [ { "pdb_id": "AF-Q2NL11-F1", "pdb_chain": "global", "start_pos": 1, "end_pos": 293, "overlap": "1.0", "method": "AlphaFold", "type": "alphafold", "resolution": -1.0, "url": "https://data.glygen.org/ln2downloads/pdb/current/AF-Q2NL11-F1.pdb", "url_external": "https://alphafold.ebi.ac.uk/entry/Q2NL11" } ], "lectin_list": [], "domain_list": [], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" }, { 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"database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P13619/entry#names_and_taxonomy" } ] }, { "name": "ATP synthase b-subunit", "type": "synonym", "evidence": [ { "id": "NP_001033590", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001033590" } ] }, { "name": "ATP synthase peripheral stalk subunit b, mitochondrial precursor", "type": "synonym", "evidence": [ { "id": "NP_001033590", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001033590" } ] }, { "name": "ATP synthase peripheral stalk subunit b, mitochondrial", "type": "synonym", "evidence": [ { "id": "NP_001033590", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001033590" } ] }, { "name": "ATP synthase peripheral stalk-membrane subunit b", "type": "synonym", "evidence": [ { "id": "P13619", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P13619/entry#names_and_taxonomy" } ] }, { "name": "ATP synthase subunit b, mitochondrial", "type": "synonym", "evidence": [ { "id": "NP_001033590", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001033590" } ] }, { "name": "ATP synthase subunit b", "type": "synonym", "evidence": [ { "id": "P13619", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P13619/entry#names_and_taxonomy" } ] }, { "name": "ATP synthase, H+ transporting, mitochondrial F0 complex, subunit B1", "type": "synonym", "evidence": [ { "id": "NP_001033590", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001033590" } ] }, { "name": "ATP synthase, H+ transporting, mitochondrial Fo complex subunit B1", "type": "synonym", "evidence": [ { "id": "NP_001033590", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001033590" } ] }, { "name": "ATPase subunit b", "type": "synonym", "evidence": [ { "id": "NP_001033590", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001033590" }, { "id": "P13619", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P13619/entry#names_and_taxonomy" } ] } ], "function": [ { "annotation": "Subunit b, of the mitochondrial membrane ATP synthase complex (F(1)F(0) ATP synthase or Complex V) that produces ATP from ADP in the presence of a proton gradient across the membrane which is generated by electron transport complexes of the respiratory chain. ATP synthase complex consist of a soluble F(1) head domain - the catalytic core - and a membrane F(1) domain - the membrane proton channel. These two domains are linked by a central stalk rotating inside the F(1) region and a stationary peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation (By similarity). In vivo, can only synthesize ATP although its ATP hydrolase activity can be activated artificially in vitro (By similarity). Part of the complex F(0) domain (By similarity). Part of the complex F(0) domain and the peripheric stalk, which acts as a stator to hold the catalytic alpha(3)beta(3) subcomplex and subunit a/ATP6 static relative to the rotary elements (Probable).", "evidence": [ { "database": "UniProtKB", "id": "P13619", "url": "https://www.uniprot.org/uniprotkb/P13619#function" }, { "database": "UniProtKB", "id": "P24539", "url": "https://www.uniprot.org/uniprotkb/P24539#function" }, { "database": "UniProtKB", "id": "P19483", "url": "https://www.uniprot.org/uniprotkb/P19483#function" }, { "database": "PubMed", "id": "25851905", "url": "https://glygen.org/publication/PubMed/25851905" }, { "database": "UniProtKB", "id": "A0A3Q1M4M4", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1M4M4#function" }, { "database": "UniProtKB", "id": "RU368017", "url": "https://www.uniprot.org/uniprotkb/RU368017#function" }, { "database": "UniProtKB", "id": "ARBA00055529", "url": "https://www.uniprot.org/uniprotkb/ARBA00055529#function" }, { "database": "UniProtKB", 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"MLSHVRLFAMDCSTPGLPVHHQLPEVLQATRIFHTGQPSLAPVPPLPEHGGKVRFGLIPEEFFQFLYPKTGVTGPYVLGTGLILYLLSKEIYVITPETFSAISTIGFLVYIVKKYGASVGEFADKLNEQKIAQLEEVKQASIKQIQDAIDMEKSQQALVQKRHYLFDVQRNNIAMALEVTYRERLHRVYREVKNRLDYHISVQNMMRQKEQEHMINWVEKRVVQSISAQQEKETIAKCIADLKLLSKKAQAQPVM", "length": 255, "header": "tr|A0AAA9S3P5-1|AT5F1_BOVIN Computationally mapped isoform of ATP synthase peripheral stalk subunit b, mitochondrial OS=Bos taurus OX=9913 GN=ATP5PB PE=1 SV=2 CANONICAL=P13619-1" }, "locus": { "chromosome": "3", "start_pos": 31860999, "end_pos": 31846770, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000123356.1", "url": "https://www.ensembl.org/id/ENSBTAT00000123356.1" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000078407.1", "url": "https://www.ensembl.org/id/ENSBTAP00000078407.1" } ] } }, { "isoform_ac": "A0AAA9S6L2-1", "url": "https://www.uniprot.org/uniprotkb/A0AAA9S6L2/entry", "sequence": { "sequence": "MRSGEARFPDSSVGVTGAGRLLCERYLTMLSRVVLSAAAAAAPSLKNAALLGPGVLQATRIFHTGQPSLAPVPPLPEHGGKVRFGLIPEEFFQFLYPKTGVTGPYVLGTGLILYLLSKEIYVITPETFSAISTIGFLVYIVKKYGASVGEFADKLNEQKIAQLEEVKQASIKQIQDAIDMEKSQQALVQKRHYLFDVQRNNIAMALEVTYRERLHRVYREVKNRLDYHISVQNMMRQKEQEHMINWVEKRVVQSISAQQEKETIAKCIADLKLLSKKAQAQPVM", "length": 284, "header": "tr|A0AAA9S6L2-1|AT5F1_BOVIN Computationally mapped isoform of ATP synthase peripheral stalk subunit b, mitochondrial OS=Bos taurus OX=9913 GN=ATP5PB PE=1 SV=1 CANONICAL=P13619-1" }, "locus": { "chromosome": "3", "start_pos": 31863986, "end_pos": 31846770, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000135625.1", "url": "https://www.ensembl.org/id/ENSBTAT00000135625.1" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000079540.1", "url": "https://www.ensembl.org/id/ENSBTAP00000079540.1" } ] } }, { "isoform_ac": "A0AAA9T537-1", "url": "https://www.uniprot.org/uniprotkb/A0AAA9T537/entry", "sequence": { "sequence": "MLSRVVLSAAAAAGPYVLGTGLILYLLSKEIYVITPETFSAISTIGFLVYIVKKYGASVGEFADKLNEQKIAQLEEVKQASIKQIQDAIDMEKSQQALVQKRHYLFDVQRNNIAMALEVTYRERLHRVYREVKNRLDYHISVQNMMRQKEQEHMINWVEKRVVQSISAQQEKETIAKCIADLKLLSKKAQAQPVM", "length": 195, "header": "tr|A0AAA9T537-1|AT5F1_BOVIN Computationally mapped isoform of ATP synthase peripheral stalk subunit b, mitochondrial OS=Bos taurus OX=9913 GN=ATP5PB PE=1 SV=1 CANONICAL=P13619-1" }, "locus": { "chromosome": "3", "start_pos": 31863294, "end_pos": 31846770, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000097480.1", "url": "https://www.ensembl.org/id/ENSBTAT00000097480.1" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000093895.1", "url": "https://www.ensembl.org/id/ENSBTAP00000093895.1" } ] } }, { "isoform_ac": "P13619-1", "url": "https://www.uniprot.org/uniprotkb/P13619/entry#P13619-1", "sequence": { "sequence": "MLSRVVLSAAAAAAPSLKNAALLGPGVLQATRIFHTGQPSLAPVPPLPEHGGKVRFGLIPEEFFQFLYPKTGVTGPYVLGTGLILYLLSKEIYVITPETFSAISTIGFLVYIVKKYGASVGEFADKLNEQKIAQLEEVKQASIKQIQDAIDMEKSQQALVQKRHYLFDVQRNNIAMALEVTYRERLHRVYREVKNRLDYHISVQNMMRQKEQEHMINWVEKRVVQSISAQQEKETIAKCIADLKLLSKKAQAQPVM", "length": 256, "header": "sp|P13619-1|AT5F1_BOVIN Isoform 1 of ATP synthase peripheral stalk subunit b, mitochondrial OS=Bos taurus OX=9913 GN=ATP5PB PE=1 SV=2 CANONICAL=P13619-1" }, "locus": {} } ], "glycosylation": [ { "glytoucan_ac": "G49108TO", "type": "O-linked", "subtype": "O-GlcNAcylation", "prediction_tool_list": [], "site_category": "reported_with_glycan", "site_category_dict": { "reported_with_glycan": true }, "site_seq": "", "relation": "attached", "comment": "O-GlcNAcylation", "icn3d_view": {}, "evidence": [ { "id": "28100784", "database": "PubMed", "url": "https://glygen.org/publication/PubMed/28100784" }, { "id": "P13619", "database": "O-GlcNAc Database", "url": "https://www.oglcnac.mcw.edu/search/?query_protein=P13619" } ], "filter_code": "000000000000000000000.xxxxxxx.00000001000000.xxxxxxx.xxxxxxxxxx.xxxxxxxxxxxxxxxxxx.xxxxx.01000" } ], "phosphorylation": [], "glycation": [], "keywords": [ "glycoprotein", "glycoprotein_reported_with_glycan" ], "publication": [ { "title": "Association of two proteolipids of unknown function with ATP synthase from bovine heart mitochondria.", "journal": "FEBS Lett.", "date": "2007", "authors": "Chen R, Runswick MJ, Carroll J, Fearnley IM, Walker JE", "evidence": [ { "database": "UniProtKB", "id": "P13619", "url": "https://www.uniprot.org/uniprotkb/P13619" } ], "reference": [ { "type": "PubMed", "id": "17570365", "url": "https://glygen.org/publication/PubMed/17570365" } ] }, { "title": "Identification of the subunits of F1F0-ATPase from bovine heart mitochondria.", "journal": "Biochemistry", "date": "1991", "authors": "Walker J E, Lutter R, Dupuis A, Runswick M J", "evidence": [ { "database": "UniProtKB", "id": "P13619", "url": "https://www.uniprot.org/uniprotkb/P13619" } ], "reference": [ { "type": "PubMed", "id": "1827992", "url": "https://glygen.org/publication/PubMed/1827992" } ] }, { "title": "Organization of Subunits in the Membrane Domain of the Bovine F-ATPase Revealed by Covalent Cross-linking.", "journal": "The Journal of biological chemistry", "date": "2015-05-22", "authors": "Lee Jennifer, Ding ShuJing, Walpole Thomas B, Holding Andrew N, Montgomery Martin G, Fearnley Ian M, Walker John E", "evidence": [ { "database": "UniProtKB", "id": "P13619", "url": "https://www.uniprot.org/uniprotkb/P13619" } ], "reference": [ { "type": "PubMed", "id": "25851905", "url": "https://glygen.org/publication/PubMed/25851905" } ] }, { "title": "Mitochondrial O-GlcNAc Transferase (mOGT) Regulates Mitochondrial Structure, Function, and Survival in HeLa Cells.", "journal": "The Journal of biological chemistry", "date": "2017", "authors": "Sacoman JL, Dagda RY, Burnham-Marusich AR, Dagda RK, Berninsone PM", "evidence": [ { "database": "O-GlcNAc Database", "id": "P13619", "url": "https://www.oglcnac.mcw.edu/search/?query_protein=P13619" } ], "reference": [ { "type": "PubMed", "id": "28100784", "url": "https://glygen.org/publication/PubMed/28100784" } ] }, { "title": "ATP synthase from bovine mitochondria. The characterization and sequence analysis of two membrane-associated sub-units and of the corresponding cDNAs.", "journal": "J. Mol. 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"NP_803460", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_803460" } ] } ], "protein_names": [ { "name": "Peroxisomal carnitine O-octanoyltransferase", "type": "recommended", "evidence": [ { "id": "O19094", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/O19094/entry#names_and_taxonomy" } ] }, { "name": "2.3.1.137", "type": "synonym", "evidence": [ { "id": "O19094", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/O19094/entry#names_and_taxonomy" } ] }, { "name": "COT", "type": "synonym", "evidence": [ { "id": "NP_803460", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_803460" }, { "id": "O19094", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/O19094/entry#names_and_taxonomy" } ] }, { "name": "peroxisomal carnitine O-octanoyltransferase", "type": "synonym", "evidence": [ { "id": "NP_803460", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_803460" } ] } ], "function": [ { "annotation": "Beta-oxidation of fatty acids. The highest activity concerns the C6 to C10 chain length substrate.", "evidence": [ { "database": "UniProtKB", "id": "O19094", "url": "https://www.uniprot.org/uniprotkb/O19094#function" }, { "database": "UniProtKB", "id": "Q9UKG9", "url": "https://www.uniprot.org/uniprotkb/Q9UKG9#function" } ] } ], "disease": [], "snv": [], "mutagenesis": [ { "start_pos": 505, "end_pos": 505, "sequence_org": "R", "sequence_mut": "N", "comment": "Increase of KM towards carnitine.", "evidence": [ { "database": "UniProtKB", "id": "O19094", "url": "https://www.uniprot.org/uniprotkb/O19094" }, { "database": "PubMed", "id": "9288928", "url": "https://glygen.org/publication/PubMed/9288928" } ] } ], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Bos taurus", "taxid": 9913, "evidence": [ { "database": "UniProtKB", "id": "O19094", "url": "https://www.uniprot.org/uniprotkb/O19094" } ], "common_name": "Bovine", "glygen_name": "Bovine", "reference_species": "Bos taurus [9913]" } ], "gene": [ { "name": "CROT", "url": "https://www.uniprot.org/uniprotkb/O19094", "locus": { "chromosome": "4", "start_pos": 33079166, "end_pos": 33144212, "strand": "+", "evidence": [ { "database": "Ensembl Gene", "id": "ENSBTAG00000021535", "url": "https://www.ensembl.org/id/ENSBTAG00000021535" } ] } } ], "crossref": [ { "id": "O19094", "url": "https://alphafold.ebi.ac.uk/entry/O19094", "database": "AlphaFoldDB", "categories": [] }, { "id": "ENSBTAG00000021535", "url": "https://bgee.org/?page=gene&gene_id=ENSBTAG00000021535", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "2.3.1.137", "url": "https://www.brenda-enzymes.org/enzyme.php?ecno=2.3.1.137&UniProtAcc=O19094", "database": "BRENDA", "categories": [ "Enzyme and Pathway" ] }, { "id": "281092", "url": "https://www.ncbi.nlm.nih.gov/gene/281092", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR000542", "url": "https://www.ebi.ac.uk/interpro/entry/IPR000542", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR023213", "url": "https://www.ebi.ac.uk/interpro/entry/IPR023213", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR039551", "url": "https://www.ebi.ac.uk/interpro/entry/IPR039551", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR042231", "url": "https://www.ebi.ac.uk/interpro/entry/IPR042231", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR042572", "url": "https://www.ebi.ac.uk/interpro/entry/IPR042572", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "bta:281092", "url": "https://www.genome.jp/dbget-bin/www_bget?bta:281092", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "DVWAKDY", "url": "https://omabrowser.org/oma/group/DVWAKDY/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "O19094", "url": "https://www.orthodb.org/?gene=O19094", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR22589", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR22589", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR22589:SF67", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR22589:SF67", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00755", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00755", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "R-BTA-389887", "url": "https://www.reactome.org/PathwayBrowser/#R-BTA-389887", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "R-BTA-9033241", "url": "https://www.reactome.org/PathwayBrowser/#R-BTA-9033241", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "NP_803460", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_803460", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "17177", "url": "https://www.rhea-db.org/rhea/17177", "database": "Rhea", "categories": [ "Enzyme and Pathway" ] }, { "id": "44860", "url": "https://www.rhea-db.org/rhea/44860", "database": "Rhea", "categories": [ "Enzyme and Pathway" ] }, { "id": "A0AAA9SDI4", "url": "https://www.uniprot.org/uniprotkb/A0AAA9SDI4", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0AAA9SDI4-1", "url": "https://www.uniprot.org/uniprotkb/A0AAA9SDI4-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0AAA9SLP1", "url": "https://www.uniprot.org/uniprotkb/A0AAA9SLP1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0AAA9SLP1-1", "url": "https://www.uniprot.org/uniprotkb/A0AAA9SLP1-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0AAA9SLQ6", "url": "https://www.uniprot.org/uniprotkb/A0AAA9SLQ6", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0AAA9SLQ6-1", "url": "https://www.uniprot.org/uniprotkb/A0AAA9SLQ6-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0AAA9TJA1", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TJA1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0AAA9TJA1-1", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TJA1-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0AAF7AMD2", "url": "https://www.uniprot.org/uniprotkb/A0AAF7AMD2", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0AAF7AMD2-1", "url": "https://www.uniprot.org/uniprotkb/A0AAF7AMD2-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "G5E5R3", "url": "https://www.uniprot.org/uniprotkb/G5E5R3", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "G5E5R3-1", "url": "https://www.uniprot.org/uniprotkb/G5E5R3-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "O19094", "url": "https://www.uniprot.org/uniprotkb/O19094", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "O19094-1", "url": "https://www.uniprot.org/uniprotkb/O19094-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MENQLAKSTEERTFQYQDSLPSLPVPSLEESLKKYLESVKPFANEEEYKNTEAIVWKFQNGIGEKLQQKLLQRAKGRRNWLEEWWLNVAYLDVRIPSQLNVNFGGPASHIEHYWPPKEGTQLERGSISLWHNLNYWQLLRKEKLAVEKVGNTPLDMNQFRMLFSTCKIPGITRDSIINYFRTESEGHSPSHLAVLCRGRVFVFDVMHEGYLMTAPEIQRQLTYIQKKCHSEPDGPGVAALTTEERTRWAKAREYLISLNPENLTILEKIQSSLLVFCLDDDSPHVTPEDYSQVSAKILNGDPTVRWGDKSYNLIAFSNGVFGSNCDHAPFDAMVLVKVCYYVDENILENEGRWKGSEKVRDIPVPEELVFTVDEKVLNDINQAKAQYFKQVSDLQLVVYAFTSFGKKLTKEKQLHPDTFIQLALQLAYYRLHGRPGCCYETAMTRLFYHGRTETVRPCTVEAVNWCQSMQNPSTSLLERKHMMLEAFAKHNKMMKDCSTGKGFDRHLLGLSLIAKEEGLPVPELFTDPLFSRSGGGGNFVLSTSLVGYLRVQGVMVPMVHNGYGFFYHIRDDRFVVSCSAWKSCPETDAEKLVQQVFHAFCDMMQLMEMPHL", "length": 612, "header": "sp|O19094-1|OCTC_BOVIN Isoform 1 of Peroxisomal carnitine O-octanoyltransferase OS=Bos taurus OX=9913 GN=CROT PE=1 SV=1 CANONICAL=O19094-1" }, "isoforms": [ { "isoform_ac": "A0AAA9SDI4-1", "url": "https://www.uniprot.org/uniprotkb/A0AAA9SDI4/entry", "sequence": { "sequence": "MENQLAKSTEERTFQYQDSLPSLPVPSLEESLKKYLESVKPFANEEEYKNTEAIVWKFQNGIGEKLQQKLLQRAKGRRNWLEEWWLNVAYLDVRIPSQLNVNFGGPASHIEHYWPPKEGTQLERGSISLWHNLNYWQLLRKEKLAVEKVGNTPLDMNQFRMLFSTCKIPGITRDSIINYFRTESEGHSPSHLAVLCRGRVFVFDVMHEGYLMTAPEIQRQLTYIQKKCHSEPDGPGVAALTTEERTRWAKAREYLISLNPENLTILEKIQSSLLVFCLDDDSPHVTPEDYSQVSAKILNGDPTVRWGDKSYNLIAFSNGVFGSNCDHAPFDAMVLVKVCYYVDENILENEGRWKGSEKVRDIPVPEELVFTVDEKVLNDINQAKAQYFKQVSDLQLVVYAFTSFGKKLTKEKQLHPDTFIQLALQLAYYRLHGRSLLNLSRIFSILVSRLFICDSILISRFWIIFTIIIWNSLSEYIMRNAGLEEAQAGIKIAGRNINNLTYADDTTLLAESEEELKKSLLMKVKVESEKVGLKLNIQKTKITASSPIASWKIDGETVETVADFIFLGSKITTDGACSHEIKRRLLLGRKVMTNLDSILKSRDITLPTKVHLVKAMVFPVVMYGCESWMRESLGLQGDPTSSS", "length": 643, "header": "tr|A0AAA9SDI4-1|OCTC_BOVIN Computationally mapped isoform of Peroxisomal carnitine O-octanoyltransferase OS=Bos taurus OX=9913 GN=CROT PE=1 SV=1 CANONICAL=O19094-1" }, "locus": { "chromosome": "4", "start_pos": 33140638, "end_pos": 33094046, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000102217.1", "url": "https://www.ensembl.org/id/ENSBTAT00000102217.1" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000080395.1", "url": "https://www.ensembl.org/id/ENSBTAP00000080395.1" } ] } }, { "isoform_ac": "A0AAA9SLP1-1", "url": "https://www.uniprot.org/uniprotkb/A0AAA9SLP1/entry", "sequence": { "sequence": "MENQLAKSTEERTFQYQDSLPSLPVPSLEESLKKYLESVKPFANEEEYKNTEAIVWKFQNGIGEKLQQKLLQRAKGRRNWVFVIVFIE", "length": 88, "header": "tr|A0AAA9SLP1-1|OCTC_BOVIN Computationally mapped isoform of Peroxisomal carnitine O-octanoyltransferase OS=Bos taurus OX=9913 GN=CROT PE=1 SV=2 CANONICAL=O19094-1" }, "locus": { "chromosome": "4", "start_pos": 33140638, "end_pos": 33136073, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000106533.2", "url": "https://www.ensembl.org/id/ENSBTAT00000106533.2" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000087274.2", "url": "https://www.ensembl.org/id/ENSBTAP00000087274.2" } ] } }, { "isoform_ac": "A0AAA9SLQ6-1", "url": "https://www.uniprot.org/uniprotkb/A0AAA9SLQ6/entry", "sequence": { "sequence": "MENQLAKSTEERTFQYQDSLPSLPVPSLEESLKKYLESVKPFANEEEYKNTEAIVWKFQNGIGEKLQQKLLQRAKGRRNWLEEWWLNVAYLDVRIPSQLNVNFGGPASHIEHYWPPKEGTQLERGSISLWHNLNYWQLLRKEKLAVEKVGNTPLDMNQFRMLFSTCKIPGITRDSIINYFRTESEGHSPSHLAVLCRGRVFVFDVMHEGYLMTAPEIQRQLTYIQKKCHSEPDGPGVAALTTEERTRWAKAREYLISLNPENLTILEKIQSSLLVFCLDDDSPHVTPEDYSQVSAKILNGDPTVRWGDKSYNLIAFSNGVFGSNCDHAPFDAMVLVKVCYYVDENILENEGRWKGSEKVRDIPVPEELVFTVDEKVLNDINQAKAQYFKQVSDLQLVVYAFTSFGKKLTKEKQLHPDTFIQLALQLAYYRLHGRPGCCYETAMTRLFYHGRTETVRPCTVEAVNWCQSMQNPSTSLLERKHMMLEAFAKHNKMMKDCSTGKGFDRHLLGLSLIAKEEGLPVPELFTDPLFSRSGGGGNFVLSTSLVGYLRVQGVMVPMVHNGYGFFYHIRDDSCWCVPCSLTLPFSITTIKSAFWMVDSR", "length": 600, "header": "tr|A0AAA9SLQ6-1|OCTC_BOVIN Computationally mapped isoform of Peroxisomal carnitine O-octanoyltransferase OS=Bos taurus OX=9913 GN=CROT PE=1 SV=1 CANONICAL=O19094-1" }, "locus": { "chromosome": "4", "start_pos": 33140638, "end_pos": 33079849, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000133352.1", "url": "https://www.ensembl.org/id/ENSBTAT00000133352.1" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000083626.1", "url": "https://www.ensembl.org/id/ENSBTAP00000083626.1" } ] } }, { "isoform_ac": "A0AAA9TJA1-1", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TJA1/entry", "sequence": { "sequence": "MENQLAKSTEERTFQYQDSLPSLPVPSLEESLKKYLESVKPFANEEEYKNTEAIVWKFQNGIGEKLQQKLLQRAKGRRNWLEEWWLNVAYLDVRIPSQLNVNFGGPASHIEHYWPPKEGTQLERGSISLWHNLNYWHLWWQNVEKEKLAVEKVGNTPLDMNQFRMLFSTCKIPGITRDSIINYFRTESEGHSPSHLAVLCRGRVFVFDVMHEGYLMTAPEIQRQLTYIQKKCHSEPDGPGVAALTTEERTRWAKAREYLISLNPENLTILEKIQSSLLVFCLDDDSPHVTPEDYSQVSAKILNGDPTVRWGDKSYNLIAFSNGVFGSNCDHAPFDAMVLVKVCYYVDENILENEGRWKGSEKVRDIPVPEELVFTVDEKVLNDINQAKAQYFKQVSDLQLVVYAFTSFGKKLTKEKQLHPDTFIQLALQLAYYRLHGRPGCCYETAMTRLFYHGRTETVRPCTVEAVNWCQSMQNPSTSLLERKHMMLEAFAKHNKMMKDCSTGKGFDRHLLGLSLIAKEEGLPVPELFTDPLFSRSGGGGNFVLSTSLVGYLRVQGVMVPMVHNGYGFFYHIRDDRFVVSCSAWKSCPETDAEKLVQQVFHAFCDMMQLMEMPHL", "length": 616, "header": "tr|A0AAA9TJA1-1|OCTC_BOVIN Computationally mapped isoform of Peroxisomal carnitine O-octanoyltransferase OS=Bos taurus OX=9913 GN=CROT PE=1 SV=1 CANONICAL=O19094-1" }, "locus": { "chromosome": "4", "start_pos": 33140638, "end_pos": 33083858, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000112611.1", "url": "https://www.ensembl.org/id/ENSBTAT00000112611.1" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000098533.1", "url": "https://www.ensembl.org/id/ENSBTAP00000098533.1" } ] } }, { "isoform_ac": "A0AAF7AMD2-1", "url": "https://www.uniprot.org/uniprotkb/A0AAF7AMD2/entry", "sequence": { "sequence": "MENQLAKSTEERTFQYQDSLPSLPVPSLEESLKKYLESVKPFANEEEYKNTEAIVWKFQNGIGEKLQQKLLQRAKGRRNWLEEWWLNVAYLDVRIPSQLNVNFGGPASHIEHYWPPKEGTQLERGSISLWHNLNYWQLLRKEKLAVEKVGNTPLDMNQFRMLFSTCKIPGITRDSIINYFRTESEGHSPSHLAVLCRGRVFVFDVMHEGYLMTAPEIQRFSNYFLGQLTYIQKKCHSEPDGPGVAALTTEERTRWAKAREYLISLNPENLTILEKIQSSLLVFCLDDDSPHVTPEDYSQVSAKILNGDPTVRWGDKSYNLIAFSNGVFGSNCDHAPFDAMVLVKVCYYVDENILENEGRWKGSEKVRDIPVPEELVFTVDEKVLNDINQAKAQYFKQVSDLQLVVYAFTSFGKKLTKEKQLHPDTFIQLALQLAYYRLHGRPGCCYETAMTRLFYHGRTETVRPCTVEAVNWCQSMQNPSTSLLERKHMMLEAFAKHNKMMKDCSTGKGFDRHLLGLSLIAKEEGLPVPELFTDPLFSRSGGGGNFVLSTSLVGYLRVQGVMVPMVHNGYGFFYHIRDDRFVVSCSAWKSCPETDAEKLVQQVFHAFCDMMQLMEMPHL", "length": 619, "header": "tr|A0AAF7AMD2-1|A0AAF7AMD2_BOVIN Computationally mapped isoform of Peroxisomal carnitine O-octanoyltransferase OS=Bos taurus OX=9913 GN=CROT PE=1 SV=1 CANONICAL=O19094-1" }, "locus": { "chromosome": "4", "start_pos": 33140638, "end_pos": 33083858, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000076118.2", "url": "https://www.ensembl.org/id/ENSBTAT00000076118.2" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000071426.2", "url": "https://www.ensembl.org/id/ENSBTAP00000071426.2" } ] } }, { "isoform_ac": "G5E5R3-1", "url": "https://www.uniprot.org/uniprotkb/G5E5R3/entry", "sequence": { "sequence": "MENQLAKSTEERTFQYQDSLPSLPVPSLEESLKKYLESVKPFANEEEYKNTEAIVWKFQNGIGEKLQQKLLQRAKGRRNWLEEWWLNVAYLDVRIPSQLNVNFGGPASHIEHYWPPKEGTQLERGSISLWHNLNYWQLLRKEKLAVEKVGNTPLDMNQFRMLFSTCKIPGITRDSIINYFRTESEGHSPSHLAVLCRGRVFVFDVMHEGYLMTAPEIQRQLTYIQKKCHSEPDGPGVAALTTEERTRWAKAREYLISLNPENLTILEKIQSSLLVFCLDDDSPHVTPEDYSQVSAKILNGDPTVRWGDKSYNLIAFSNGVFGSNCDHAPFDAMVLVKVCYYVDENILENEGRWKGSEKVRDIPVPEELVFTVDEKVLNDINQAKAQYFKQVSDLQLVVYAFTSFGKKLTKEKQLHPDTFIQLALQLAYYRLHGRPGCCYETAMTRLFYHGRTETVRPCTVEAVNWCQSMQNPSTSLLERKHMMLEAFAKHNKMMKDCSTGKGFDRHLLGLSLIAKEEGLPVPELFTDPLFSRSGGGGNFVLSTSLVGYLRVQGVMVPMVHNGYGFFYHIRDDRL", "length": 574, "header": "tr|G5E5R3-1|OCTC_BOVIN Computationally mapped isoform of Peroxisomal carnitine O-octanoyltransferase OS=Bos taurus OX=9913 GN=CROT PE=1 SV=3 CANONICAL=O19094-1" }, "locus": { "chromosome": "4", "start_pos": 33140638, "end_pos": 33084193, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000028699.7", "url": "https://www.ensembl.org/id/ENSBTAT00000028699.7" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000028699.7", "url": "https://www.ensembl.org/id/ENSBTAP00000028699.7" } ] } }, { "isoform_ac": "O19094-1", "url": "https://www.uniprot.org/uniprotkb/O19094/entry#O19094-1", "sequence": { "sequence": "MENQLAKSTEERTFQYQDSLPSLPVPSLEESLKKYLESVKPFANEEEYKNTEAIVWKFQNGIGEKLQQKLLQRAKGRRNWLEEWWLNVAYLDVRIPSQLNVNFGGPASHIEHYWPPKEGTQLERGSISLWHNLNYWQLLRKEKLAVEKVGNTPLDMNQFRMLFSTCKIPGITRDSIINYFRTESEGHSPSHLAVLCRGRVFVFDVMHEGYLMTAPEIQRQLTYIQKKCHSEPDGPGVAALTTEERTRWAKAREYLISLNPENLTILEKIQSSLLVFCLDDDSPHVTPEDYSQVSAKILNGDPTVRWGDKSYNLIAFSNGVFGSNCDHAPFDAMVLVKVCYYVDENILENEGRWKGSEKVRDIPVPEELVFTVDEKVLNDINQAKAQYFKQVSDLQLVVYAFTSFGKKLTKEKQLHPDTFIQLALQLAYYRLHGRPGCCYETAMTRLFYHGRTETVRPCTVEAVNWCQSMQNPSTSLLERKHMMLEAFAKHNKMMKDCSTGKGFDRHLLGLSLIAKEEGLPVPELFTDPLFSRSGGGGNFVLSTSLVGYLRVQGVMVPMVHNGYGFFYHIRDDRFVVSCSAWKSCPETDAEKLVQQVFHAFCDMMQLMEMPHL", "length": 612, "header": "sp|O19094-1|OCTC_BOVIN Isoform 1 of Peroxisomal carnitine O-octanoyltransferase OS=Bos taurus OX=9913 GN=CROT PE=1 SV=1 CANONICAL=O19094-1" }, "locus": {} } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [ "enzyme" ], "publication": [ { "title": "cDNA cloning, recombinant expression, and site-directed mutagenesis of bovine liver carnitine octanoyltransferase--Arg505 binds the carboxylate group of carnitine.", "journal": "European journal of biochemistry", "date": "1997-08-01", "authors": "Cronin C N", "evidence": [ { "database": "UniProtKB", "id": "O19094", "url": "https://www.uniprot.org/uniprotkb/O19094" } ], "reference": [ { "type": "PubMed", "id": "9288928", "url": "https://glygen.org/publication/PubMed/9288928" } ] } ], "pathway": [ { "id": "bta:281092", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?bta:281092", "resource": "KEGG Pathway" }, { "id": "R-BTA-389887", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-BTA-389887", "resource": "Reactome", "description": "Beta-oxidation of pristanoyl-CoA" }, { "id": "R-BTA-9033241", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-BTA-9033241", "resource": "Reactome", "description": "Peroxisomal protein import" } ], "orthologs": [ { "uniprot_canonical_ac": "A0A287B7Y5-1", "protein_name": "Peroxisomal carnitine O-octanoyltransferase", "gene_name": "CROT", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MESQLAKSTEERTFQYQDSLPSLPVPSLEESLKKYLESVKPFANEEEYKKTEAIVQKFQNGIGEKLQKKLLERAKGKRNWLEEWWLNVAYLDVRTPSQLNVNFAGPAPHIENYWPPKEGTQLERGSICLWHVLNYWQLLRKEKIPVQKVGNTPLDMYQFRMLFATCKVPGITRDSVMNYFRTESEGYCPTHVAVLCRGRVFIFDVMHKGCLVTPPEILRQLTFVQKKCHSEPDGPGIAALTSEERTRWAKAREYLIRLNPENLTLLEKIESSLLVYSLEDGSPHVTPEDYSQVTAEILTGNPTVRWGDKSYNLISFSNGVFGCSCDHSPFDAMVMVNLSHYIDQKVLENEGRWKGSEKVREIPLPEELVFTVDEKVLNDINQAKAQYFMQASDLQLVVYAFTSFGKKQTKKKQLHPDAFIQLALQLGYYRLHGRPGCCYETAMTRYFYHGRTETMRSCTVEAVSWCQSMQDPSTSLSERQHKMLEAFAKHNKMMKDCSAGKGFDRHLLGLSLIAKEEGLPVPELFTDPLFSRSGGGGNFVLSTSLVGYFRIQGAVVPMVHNGYGFFYHIRDDRFLVSCTAWKSCPETDAEKLVQQVFCAFHDMMQLMNIAKL", "length": 612 }, "evidence": [ { "id": "O19094", "url": "https://omabrowser.org/oma/group/O19094/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "A0A8V0XIT0-1", "protein_name": "Peroxisomal carnitine O-octanoyltransferase", "gene_name": "CROT", "tax_id": 9031, "organism": "Gallus gallus", "sequence": { "sequence": "MEKQVLESSEERTFQYQDSLPPLPVPPLDESLSKYLDSVKPFLNQEEYQRTEDIVKRFENGIGKELHQKLLERAKTRRNWLEDWWLNVAYLDLRISTQINCNMGGPGPYIEHCWPPKEGTQIERACVNIWHTLKYWELLREEKAPIERSGNAVLDMSQFRMLFNTCKVPGITRDSLCNYFKTVTEGECPSHLVVLCRGRVFAFDAVHEGNMLTPPELSRQLTFIQRRCDSEPDGPGLPALTSNERTKWAEIREYLISLDPKNLAHLEKIQQSLFVVSLDDSSPHATPEDYTEITRLGLAGDPTVRWGDKSYNSIFFSNGTSSAFCDHSPFDAMALITMLSSAEQKIIENEGKWKGSDKVRDIPCPEELVFTVDQKIINEIERTKEMYYEKVSDLQLACYAFTSFGKALIKKRKLHPDTFVQLALQLAYYKCHGRPGCCYETAMTRRFYHGRTETIRPCTMEAVEWCKSMLDHSATNYERLQLMHAAFAKHNRMRKDCENGRGFDRHLLGLLLIAQEQGLPVPELFEDPAFTASGGGGNFVLSTSLTGYTRFSGCAVPMVHHGYGFFYAIRDDRIVVLCSSWKSCPETSAEVLCKTLFQCFQDVLQLTVTAQL", "length": 612 }, "evidence": [ { "id": "O19094", "url": "https://omabrowser.org/oma/group/O19094/", "database": "OMA" } ], "glygen_name": "Chicken", "common_name": "Chicken" }, { "uniprot_canonical_ac": "Q9DC50-1", "protein_name": "Peroxisomal carnitine O-octanoyltransferase", "gene_name": "Crot", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MENQLTKSVEERTFQYQDSLPSLPVPALEESLKKYLESVKPFANEDEYKKTEEIVQKFQEGAGKRLHQKLLERARGKRNWLEEWWLNVAYLDVRIPSQLNVNFVGPCPHFEHYWPAREGTQLERGSMMLWHNLNYWQLLRREKLPVHKSGNTPLDMNQFRMLFSTCKVPGITRDSIMNYFKTESEGHCPTHIAVLCRGRAFVFDVLHEGCLITPPELLRQLTYIHKKCSNEPVGPSIAALTSEERTRWAKAREYLISLDPENLTLLEKIQTSLFVYSIEDSSPHATPEEYSQVFEMLLGGDPSVRWGDKSYNLISFANGIFGCCCDHAPYDAMVMVNIAHYVDERVLETEGRWKGSEKVRDIPLPEELVFTVDEKILNDVSQAKAQHLKAASDLQIAASTFTSFGKKLTKEEALHPDTFIQLALQLAYYRLHGRPGCCYETAMTRYFYHGRTETVRSCTVEAVRWCQSMQDPSASLLERQQKMLEAFAKHNKMMKDCSHGKGFDRHLLGLLLIAKEEGLPVPELFEDPLFSRSGGGGNFVLSTSLVGYLRVQGVVVPMVHNGYGFFYHIRDDRFVVACSSWRSCPETDAEKLVQMIFHAFHDMIQLMNTAHL", "length": 612 }, "evidence": [ { "id": "O19094", "url": "https://omabrowser.org/oma/group/O19094/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q9UKG9-1", "protein_name": "Peroxisomal carnitine O-octanoyltransferase", "gene_name": "CROT", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MENQLAKSTEERTFQYQDSLPSLPVPSLEESLKKYLESVKPFANQEEYKKTEEIVQKFQSGIGEKLHQKLLERAKGKRNWLEEWWLNVAYLDVRIPSQLNVNFAGPAAHFEHYWPPKEGTQLERGSITLWHNLNYWQLLRKEKVPVHKVGNTPLDMNQFRMLFSTCKVPGITRDSIMNYFRTESEGRSPNHIVVLCRGRAFVFDVIHEGCLVTPPELLRQLTYIHKKCHSEPDGPGIAALTSEERTRWAKAREYLIGLDPENLALLEKIQSSLLVYSMEDSSPHVTPEDYSEIIAAILIGDPTVRWGDKSYNLISFSNGVFGCNCDHAPFDAMIMVNISYYVDEKIFQNEGRWKGSEKVRDIPLPEELIFIVDEKVLNDINQAKAQYLREASDLQIAAYAFTSFGKKLTKNKMLHPDTFIQLALQLAYYRLHGHPGCCYETAMTRHFYHGRTETMRSCTVEAVRWCQSMQDPSVNLRERQQKMLQAFAKHNKMMKDCSAGKGFDRHLLGLLLIAKEEGLPVPELFTDPLFSKSGGGGNFVLSTSLVGYLRVQGVVVPMVHNGYGFFYHIRDDRFVVACSAWKSCPETDAEKLVQLTFCAFHDMIQLMNSTHL", "length": 612 }, "evidence": [ { "id": "O19094", "url": "https://omabrowser.org/oma/group/O19094/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "Q9VB02-1", "protein_name": "Carnitine O-octanoyltransferase, isoform A", "gene_name": "CROT", "tax_id": 7227, "organism": "Drosophila melanogaster", "sequence": { "sequence": "MDRASLYFMSKDDKNTFDFDETLPSLPLPELRDTMERYYSCIQPFGTKEELAQARKTIDEFQNGVGAQLHEQLKKRAAGMRNWLGTWWEDYGYHLIRMPLLPYQLMVMPSQLEMVGVPETPEYMLKSLARHIHHSLEFWDLTRKSSIKPLSSNGGKIKYSSALYKHFFSTCRVPGEEQDHIEKHFLTKDEGKTPSHMLISGKGRQFIFDCVHEDDTILSAPEILVALQRVRSILDYEPLGDCVPTLSHDERSTWARNRNRLREISVANKETLLLVESACMEICWYEQSPKDYEESCQLGLYGDLHSRWADRSSSIIAFRNGRCNWTGEHSCYDGTVSISYATFMQLSFLEVPEPDWAEAEKGNVLEVKELHFQLDDTLKNEIKRVQKDIDDRGIDVTVTFTAFDDYGKDFMKTHRLHPDSFVQVVMQWAYYQMHKEIAPTYETALMRQYYNGRTETLRSCTSAVAEFLRASSNKQVGDMSLARAFRRAVDEHKHFMNEARKGHGIDRHLFGLWCAAYESKMDIPAFYDDPMYTKSGGGGNFVLSSSTLGFTANVGFVAPMVFDGYGVFYSITSEAVFINTTAYRDSLKTSARKFNDIFKDSFRRISVLLEQLAKESKL", "length": 618 }, "evidence": [ { "id": "O19094", "url": "https://omabrowser.org/oma/group/O19094/", "database": "OMA" } ], "glygen_name": "Fruit fly", "common_name": "Fruit fly" } ], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 1, "go_terms": [ { "name": "peroxisome", "id": "GO:0005777", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005777", "evidence": [ { "database": "UniProtKB", "id": "O19094", "url": "https://www.uniprot.org/uniprotkb/O19094" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 6, "go_terms": [ { "name": "generation of precursor metabolites and energy", "id": "GO:0006091", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006091", "evidence": [ { "database": "UniProtKB", "id": "O19094", "url": "https://www.uniprot.org/uniprotkb/O19094" } ], "pmid": "" }, { "name": "fatty acid metabolic process", "id": "GO:0006631", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006631", "evidence": [ { "database": "UniProtKB", "id": "O19094", "url": "https://www.uniprot.org/uniprotkb/O19094" } ], "pmid": "" }, { "name": "fatty acid beta-oxidation", "id": "GO:0006635", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006635", "evidence": [ { "database": "UniProtKB", "id": "O19094", "url": "https://www.uniprot.org/uniprotkb/O19094" } ], "pmid": "" }, { "name": "medium-chain fatty acid metabolic process", "id": "GO:0051791", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0051791", "evidence": [ { "database": "UniProtKB", "id": "O19094", "url": "https://www.uniprot.org/uniprotkb/O19094" } ], "pmid": "" }, { "name": "coenzyme A metabolic process", "id": "GO:0015936", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0015936", "evidence": [ { "database": "UniProtKB", "id": "O19094", "url": "https://www.uniprot.org/uniprotkb/O19094" } ], "pmid": "" }, { "name": "carnitine metabolic process", "id": "GO:0009437", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0009437", "evidence": [ { "database": "UniProtKB", "id": "O19094", "url": "https://www.uniprot.org/uniprotkb/O19094" } ], "pmid": "" } ] }, { "name": "Molecular Function", "total": 2, "go_terms": [ { "name": "carnitine O-octanoyltransferase activity", "id": "GO:0008458", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008458", "evidence": [ { "database": "UniProtKB", "id": "O19094", "url": "https://www.uniprot.org/uniprotkb/O19094" } ], "pmid": "" }, { "name": "acyltransferase activity, transferring groups other than amino-acyl groups", "id": "GO:0016747", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016747", "evidence": [ { "database": "UniProtKB", "id": "O19094", "url": "https://www.uniprot.org/uniprotkb/O19094" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 262, "end_pos": 264, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [ { "id": "17177", "name": "", "equation": "octanoyl-CoA + (R)-carnitine = O-octanoyl-(R)-carnitine + CoA", "summary": "", "cellular_location": "", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [ "Q2KJB7-1", "F1N1M7-1", "O19094-1", "A0A3Q1LYY4-1" ], "evidence": [ { "id": "17177", "database": "Rhea", "url": "https://www.rhea-db.org/rhea/17177" } ] }, { "id": "44860", "name": "", "equation": "4,8-dimethylnonanoyl-CoA + (R)-carnitine = O-4,8-dimethylnonanoyl-(R)-carnitine + CoA", "summary": "", "cellular_location": "", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [ "O19094-1", "A0A3Q1LYY4-1", "Q2KJB7-1", "F1N1M7-1" ], "evidence": [ { "id": "44860", "database": "Rhea", "url": "https://www.rhea-db.org/rhea/44860" } ] }, { "id": "R-BTA-390281", "name": "4,8-dimethylnonanoyl-CoA + carnitine => 4,8-dimethylnonanoylcarnitine + CoASH", "equation": "", "summary": "This event has been computationally inferred from an event that has been demonstrated in another species.

The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.

More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "cellular_location": "peroxisomal matrix", "input_participant_list": [ "R-ALL-390271", "R-ALL-390294" ], "output_participant_list": [ "R-ALL-390290" ], "enzyme_list": [ "O19094-1" ], "evidence": [ { "id": "R-BTA-390281", "database": "Reactome", "url": "https://www.reactome.org/PathwayBrowser/#R-BTA-390281" } ] }, { "id": "R-BTA-9033235", "name": "Cargo of PEX5S,L translocates from the cytosol to the peroxisomal matrix", "equation": "", "summary": "This event has been computationally inferred from an event that has been demonstrated in another species.

The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.

More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "cellular_location": "peroxisomal membrane", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [ "A0A3Q1LQH8-1", "Q3SZP5-1", "A0AAA9TBR3-1", "A0AAA9TZC7-1", "A0A3Q1LS67-1", "A0AAA9SXG3-1", "F1MYR5-1", "O19094-1", "Q29448-1", "Q3SX23-1", "F1MQP2-1", "F1MVP8-1", "A0AAA9TYP4-1", "Q24K02-1", "F6RWU6-1", "A0A3Q1LTU2-1", "A0A3Q1LYY4-1", "A0AAA9TW47-1", "A0AAA9SND8-1", "F1MV74-1", "P00432-1", "A0A140T8A5-1", "Q29RU9-1", "Q3ZBW2-1", "A0AAA9SC38-1", "A0AAA9SAI8-1" ], "evidence": [ { "id": "R-BTA-9033235", "database": "Reactome", "url": "https://www.reactome.org/PathwayBrowser/#R-BTA-9033235" } ] }, { "id": "R-BTA-9033236", "name": "PEX5S,L:Cargo binds PEX13:PEX14:PEX2:PEX10:PEX12 (Docking and Translocation Module)", "equation": "", "summary": "This event has been computationally inferred from an event that has been demonstrated in another species.

The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.

More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "cellular_location": "peroxisomal membrane", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [ "A0A3Q1LQH8-1", "Q3SZP5-1", "A0AAA9TBR3-1", "A0AAA9TZC7-1", "A0A3Q1LS67-1", "A0AAA9SXG3-1", "F1MYR5-1", "O19094-1", "Q29448-1", "Q3SX23-1", "F1MQP2-1", "F1MVP8-1", "A0AAA9TYP4-1", "Q24K02-1", "F6RWU6-1", "A0A3Q1LTU2-1", "A0A3Q1LYY4-1", "A0AAA9TW47-1", "A0AAA9SND8-1", "F1MV74-1", "P00432-1", "A0A140T8A5-1", "Q29RU9-1", "Q3ZBW2-1", "A0AAA9SC38-1", "A0AAA9SAI8-1" ], "evidence": [ { "id": "R-BTA-9033236", "database": "Reactome", "url": "https://www.reactome.org/PathwayBrowser/#R-BTA-9033236" } ] } ], "reaction_participants": [ { "participant_id": "R-ALL-390271", "participant_name": "4,8-dimethylnonanoyl-CoA [peroxisomal matrix]", "crossref": [ { "id": "77061", "database": "ChEBI", "url": "" }, { "id": "ZINC000096014568", "database": "ZINC", "url": "" } ] }, { "participant_id": "R-ALL-390290", "participant_name": "4,8-dimethylnonanoylcarnitine [peroxisomal matrix]", "crossref": [ { "id": "ZINC000032790391", "database": "ZINC", "url": "" }, { "id": "84654", "database": "ChEBI", "url": "" }, { "id": "ZINC000032790389", "database": "ZINC", "url": "" } ] }, { "participant_id": "R-ALL-390294", "participant_name": "CAR [peroxisomal matrix]", "crossref": [ { "id": "16347", "database": "ChEBI", "url": "" }, { "id": "C00318", "database": "COMPOUND", "url": "" }, { "id": "4780", "database": "Guide to Pharmacology - Ligands", "url": "" }, { "id": "ZINC000003079340", "database": "ZINC", "url": "" }, { "id": "HMDB0000062", "database": "HMDB Metabolite", "url": "" }, { "id": "C00487", "database": "COMPOUND", "url": "" } ] } ], "reaction_enzymes": [ { "uniprot_ac": "A0A140T8A5", "gene_name": "IDH1", "activity": [ { "ec_number": "1.1.1.42", "activity": "D-threo-isocitrate + NADP(+) = 2-oxoglutarate + CO2 + NADPH.", "evidence": [ { "id": "A0A140T8A5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A140T8A5" } ] }, { "ec_number": "1.1.1.42", "activity": "", "evidence": [ { "id": "A0A140T8A5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A140T8A5" } ] } ] }, { "uniprot_ac": "A0A3Q1LQH8", "gene_name": "GNPAT", "activity": [ { "ec_number": "2.3.1.42", "activity": "dihydroxyacetone phosphate + an acyl-CoA = a 1-acylglycerone 3-phosphate + CoA.", "evidence": [ { "id": "A0A3Q1LQH8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1LQH8" } ] }, { "ec_number": "2.3.1.42", "activity": "", "evidence": [ { "id": "A0A3Q1LQH8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1LQH8" } ] } ] }, { "uniprot_ac": "A0A3Q1LS67", "gene_name": "ECH1", "activity": [ { "ec_number": "5.3.3.21", "activity": "a (3E,5Z)-dienoyl-CoA = a (2E,4E)-(5,6-saturated)-dienoyl-CoA.", "evidence": [ { "id": "A0A3Q1LS67", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1LS67" } ] }, { "ec_number": "5.3.3.21", "activity": "", "evidence": [ { "id": "A0A3Q1LS67", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1LS67" } ] } ] }, { "uniprot_ac": "A0A3Q1LTU2", "gene_name": "PEX10", "activity": [ { "ec_number": "2.3.2.27", "activity": "S-ubiquitinyl-[E2 ubiquitin-conjugating enzyme]-L-cysteine + [acceptor protein]-L-lysine = [E2 ubiquitin-conjugating enzyme]-L-cysteine + N(6)-ubiquitinyl-[acceptor protein]-L-lysine.", "evidence": [ { "id": "A0A3Q1LTU2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1LTU2" } ] }, { "ec_number": "2.3.2.27", "activity": "", "evidence": [ { "id": "A0A3Q1LTU2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1LTU2" } ] } ] }, { "uniprot_ac": "A0A3Q1LYY4", "gene_name": "CRAT", "activity": [ { "ec_number": "2.3.1.137", "activity": "octanoyl-CoA + (R)-carnitine = O-octanoyl-(R)-carnitine + CoA.", "evidence": [ { "id": "A0A3Q1LYY4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1LYY4" } ] }, { "ec_number": "2.3.1.7", "activity": "(R)-carnitine + acetyl-CoA = O-acetyl-(R)-carnitine + CoA.", "evidence": [ { "id": "A0A3Q1LYY4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1LYY4" } ] }, { "ec_number": "2.3.1.137", "activity": "", "evidence": [ { "id": "A0A3Q1LYY4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1LYY4" } ] }, { "ec_number": "2.3.1.7", "activity": "", "evidence": [ { "id": "A0A3Q1LYY4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1LYY4" } ] } ] }, { "uniprot_ac": "A0AAA9SAI8", "gene_name": "TYSND1", "activity": [ { "ec_number": "3.4.21.-", "activity": "", "evidence": [ { "id": "A0AAA9SAI8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9SAI8" } ] } ] }, { "uniprot_ac": "A0AAA9SC38", "gene_name": "HAO1", "activity": [ { "ec_number": "1.1.3.15", "activity": "glycolate + O2 = glyoxylate + H2O2.", "evidence": [ { "id": "A0AAA9SC38", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9SC38" } ] }, { "ec_number": "1.1.3.15", "activity": "", "evidence": [ { "id": "A0AAA9SC38", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9SC38" } ] } ] }, { "uniprot_ac": "A0AAA9SND8", "gene_name": "EHHADH", "activity": [ { "ec_number": "1.1.1.35", "activity": "a (3S)-3-hydroxyacyl-CoA + NAD(+) = a 3-oxoacyl-CoA + NADH + H(+).", "evidence": [ { "id": "A0AAA9SND8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9SND8" } ] }, { "ec_number": "4.2.1.17", "activity": "(3S)-3-hydroxyadipyl-CoA = (E)-2,3-didehydroadipoyl-CoA + H2O.", "evidence": [ { "id": "A0AAA9SND8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9SND8" } ] }, { "ec_number": "5.3.3.8", "activity": "a (3Z)-enoyl-CoA = a 4-saturated (2E)-enoyl-CoA.", "evidence": [ { "id": "A0AAA9SND8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9SND8" } ] }, { "ec_number": "4.2.1.17", "activity": "", "evidence": [ { "id": "A0AAA9SND8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9SND8" } ] }, { "ec_number": "1.1.1.35", "activity": "", "evidence": [ { "id": "A0AAA9SND8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9SND8" } ] }, { "ec_number": "5.3.3.8", "activity": "", "evidence": [ { "id": "A0AAA9SND8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9SND8" } ] } ] }, { "uniprot_ac": "A0AAA9SXG3", "gene_name": "DAO", "activity": [ { "ec_number": "1.4.3.3", "activity": "D-lysine + O2 + H2O = 6-amino-2-oxohexanoate + H2O2 + NH4(+).", "evidence": [ { "id": "A0AAA9SXG3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9SXG3" } ] }, { "ec_number": "1.4.3.3", "activity": "", "evidence": [ { "id": "A0AAA9SXG3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9SXG3" } ] } ] }, { "uniprot_ac": "A0AAA9TBR3", "gene_name": "PAOX", "activity": [ { "ec_number": "1.5.3.13", "activity": "N(1)-acetylspermine + O2 + H2O = 3-acetamidopropanal + spermidine + H2O2.", "evidence": [ { "id": "A0AAA9TBR3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TBR3" } ] }, { "ec_number": "1.5.3.13", "activity": "", "evidence": [ { "id": "A0AAA9TBR3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TBR3" } ] } ] }, { "uniprot_ac": "A0AAA9TW47", "gene_name": "GSTK1", "activity": [ { "ec_number": "2.5.1.18", "activity": "RX + glutathione = an S-substituted glutathione + a halide anion + H(+).", "evidence": [ { "id": "A0AAA9TW47", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TW47" } ] }, { "ec_number": "2.5.1.18", "activity": "", "evidence": [ { "id": "A0AAA9TW47", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TW47" } ] } ] }, { "uniprot_ac": "A0AAA9TYP4", "gene_name": "PECR", "activity": [ { "ec_number": "1.3.1.38", "activity": "a (2E)-enoyl-CoA + NADPH + H(+) = a 2,3-saturated acyl-CoA + NADP(+).", "evidence": [ { "id": "A0AAA9TYP4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TYP4" } ] }, { "ec_number": "1.3.1.38", "activity": "", "evidence": [ { "id": "A0AAA9TYP4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TYP4" } ] } ] }, { "uniprot_ac": "A0AAA9TZC7", "gene_name": "ECI2", "activity": [ { "ec_number": "5.3.3.8", "activity": "a (3Z)-enoyl-CoA = a 4-saturated (2E)-enoyl-CoA.", "evidence": [ { "id": "A0AAA9TZC7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TZC7" } ] }, { "ec_number": "5.3.3.8", "activity": "", "evidence": [ { "id": "A0AAA9TZC7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TZC7" } ] } ] }, { "uniprot_ac": "F1MQP2", "gene_name": "SLC27A2", "activity": [ { "ec_number": "6.2.1.3", "activity": "a long-chain fatty acid + ATP + CoA = a long-chain fatty acyl-CoA + AMP + diphosphate.", "evidence": [ { "id": "F1MQP2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MQP2" } ] }, { "ec_number": "6.2.1.3", "activity": "", "evidence": [ { "id": "F1MQP2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MQP2" } ] } ] }, { "uniprot_ac": "F1MV74", "gene_name": "SCP2", "activity": [ { "ec_number": "2.3.1.176", "activity": "4,8,12-trimethyltridecanoyl-CoA + propanoyl-CoA = 3-oxopristanoyl-CoA + CoA.", "evidence": [ { "id": "F1MV74", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MV74" } ] }, { "ec_number": "2.3.1.16", "activity": "an acyl-CoA + acetyl-CoA = a 3-oxoacyl-CoA + CoA.", "evidence": [ { "id": "F1MV74", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MV74" } ] }, { "ec_number": "2.3.1.155", "activity": "tetradecanoyl-CoA + acetyl-CoA = 3-oxohexadecanoyl-CoA + CoA.", "evidence": [ { "id": "F1MV74", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MV74" } ] }, { "ec_number": "2.3.1.16", "activity": "", "evidence": [ { "id": "F1MV74", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MV74" } ] }, { "ec_number": "2.3.1.155", "activity": "", "evidence": [ { "id": "F1MV74", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MV74" } ] }, { "ec_number": "2.3.1.176", "activity": "", "evidence": [ { "id": "F1MV74", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MV74" } ] } ] }, { "uniprot_ac": "F1MVP8", "gene_name": "HACL1", "activity": [ { "ec_number": "4.1.2.63", "activity": "2-hydroxy-3-methylhexadecanoyl-CoA = 2-methylpentadecanal + formyl-CoA.", "evidence": [ { "id": "F1MVP8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MVP8" } ] }, { "ec_number": "4.1.2.63", "activity": "", "evidence": [ { "id": "F1MVP8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MVP8" } ] } ] }, { "uniprot_ac": "F1MYR5", "gene_name": "NOS2", "activity": [ { "ec_number": "1.14.13.39", "activity": "2 L-arginine + 3 NADPH + 4 O2 + H(+) = 2 L-citrulline + 2 nitric oxide + 3 NADP(+) + 4 H2O.", "evidence": [ { "id": "F1MYR5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MYR5" } ] }, { "ec_number": "1.14.13.39", "activity": "", "evidence": [ { "id": "F1MYR5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1MYR5" } ] } ] }, { "uniprot_ac": "F1N1M7", "gene_name": "CPT2", "activity": [ { "ec_number": "2.3.1.21", "activity": "(R)-carnitine + hexadecanoyl-CoA = O-hexadecanoyl-(R)-carnitine + CoA.", "evidence": [ { "id": "F1N1M7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1N1M7" } ] }, { "ec_number": "2.3.1.21", "activity": "", "evidence": [ { "id": "F1N1M7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1N1M7" } ] } ] }, { "uniprot_ac": "F6RWU6", "gene_name": "ACOT8", "activity": [ { "ec_number": "3.1.2.2", "activity": "hexadecanoyl-CoA + H2O = hexadecanoate + CoA + H(+).", "evidence": [ { "id": "F6RWU6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F6RWU6" } ] }, { "ec_number": "3.1.2.27", "activity": "(3S)-3-hydroxy-3-methylglutaryl-CoA + H2O = 3-hydroxy-3-methylglutarate + CoA + H(+).", "evidence": [ { "id": "F6RWU6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F6RWU6" } ] }, { "ec_number": "3.1.2.1", "activity": "acetyl-CoA + H2O = acetate + CoA + H(+).", "evidence": [ { "id": "F6RWU6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F6RWU6" } ] }, { "ec_number": "3.1.2.11", "activity": "acetoacetyl-CoA + H2O = acetoacetate + CoA + H(+).", "evidence": [ { "id": "F6RWU6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F6RWU6" } ] }, { "ec_number": "3.1.2.3", "activity": "succinyl-CoA + H2O = succinate + CoA + H(+).", "evidence": [ { "id": "F6RWU6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F6RWU6" } ] }, { "ec_number": "3.1.2.5", "activity": "(3S)-3-hydroxy-3-methylglutaryl-CoA + H2O = 3-hydroxy-3-methylglutarate + CoA + H(+).", "evidence": [ { "id": "F6RWU6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F6RWU6" } ] }, { "ec_number": "3.1.2.11", "activity": "", "evidence": [ { "id": "F6RWU6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F6RWU6" } ] }, { "ec_number": "3.1.2.5", "activity": "", "evidence": [ { "id": "F6RWU6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F6RWU6" } ] }, { "ec_number": "3.1.2.27", "activity": "", "evidence": [ { "id": "F6RWU6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F6RWU6" } ] }, { "ec_number": "3.1.2.2", "activity": "", "evidence": [ { "id": "F6RWU6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F6RWU6" } ] }, { "ec_number": "3.1.2.3", "activity": "", "evidence": [ { "id": "F6RWU6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F6RWU6" } ] }, { "ec_number": "3.1.2.1", "activity": "", "evidence": [ { "id": "F6RWU6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F6RWU6" } ] } ] }, { "uniprot_ac": "O19094", "gene_name": "CROT", "activity": [ { "ec_number": "2.3.1.137", "activity": "octanoyl-CoA + (R)-carnitine = O-octanoyl-(R)-carnitine + CoA.", "evidence": [ { "id": "O19094", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/O19094" } ] }, { "ec_number": "2.3.1.137", "activity": "", "evidence": [ { "id": "O19094", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/O19094" } ] } ] }, { "uniprot_ac": "P00432", "gene_name": "CAT", "activity": [ { "ec_number": "1.11.1.6", "activity": "2 H2O2 = O2 + 2 H2O.", "evidence": [ { "id": "P00432", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P00432" } ] }, { "ec_number": "1.11.1.6", "activity": "", "evidence": [ { "id": "P00432", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P00432" } ] } ] }, { "uniprot_ac": "Q24K02", "gene_name": "IDE", "activity": [ { "ec_number": "3.4.24.56", "activity": "Degradation of insulin, glucagon and other polypeptides. No action on proteins.", "evidence": [ { "id": "Q24K02", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q24K02" } ] }, { "ec_number": "3.4.24.56", "activity": "", "evidence": [ { "id": "Q24K02", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q24K02" } ] } ] }, { "uniprot_ac": "Q29448", "gene_name": "HMGCL", "activity": [ { "ec_number": "4.1.3.4", "activity": "(3S)-3-hydroxy-3-methylglutaryl-CoA = acetoacetate + acetyl-CoA.", "evidence": [ { "id": "Q29448", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q29448" } ] }, { "ec_number": "4.1.3.4", "activity": "", "evidence": [ { "id": "Q29448", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q29448" } ] } ] }, { "uniprot_ac": "Q29RU9", "gene_name": "PIPOX", "activity": [ { "ec_number": "1.5.3.1", "activity": "sarcosine + O2 + H2O = formaldehyde + glycine + H2O2.", "evidence": [ { "id": "Q29RU9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q29RU9" } ] }, { "ec_number": "1.5.3.7", "activity": "L-pipecolate + O2 = L-1-piperideine-6-carboxylate + H2O2 + H(+).", "evidence": [ { "id": "Q29RU9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q29RU9" } ] }, { "ec_number": "1.5.3.1", "activity": "", "evidence": [ { "id": "Q29RU9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q29RU9" } ] }, { "ec_number": "1.5.3.7", "activity": "", "evidence": [ { "id": "Q29RU9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q29RU9" } ] } ] }, { "uniprot_ac": "Q2KJB7", "gene_name": "CPT2", "activity": [ { "ec_number": "2.3.1.21", "activity": "(R)-carnitine + hexadecanoyl-CoA = O-hexadecanoyl-(R)-carnitine + CoA.", "evidence": [ { "id": "Q2KJB7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q2KJB7" } ] }, { "ec_number": "2.3.1.21", "activity": "", "evidence": [ { "id": "Q2KJB7", "database": "UniProtKB", "url": 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"UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q3SZP5" } ] } ] }, { "uniprot_ac": "Q3ZBW2", "gene_name": "HAO2", "activity": [ { "ec_number": "1.1.3.15", "activity": "glycolate + O2 = glyoxylate + H2O2.", "evidence": [ { "id": "Q3ZBW2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q3ZBW2" } ] }, { "ec_number": "1.1.3.15", "activity": "", "evidence": [ { "id": "Q3ZBW2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q3ZBW2" } ] } ] } ], "biomarkers": [], "structures": [ { "pdb_id": "AF-O19094-F1", "pdb_chain": "global", "start_pos": 1, "end_pos": 612, "overlap": "1.0", "method": "AlphaFold", "type": "alphafold", "resolution": -1.0, "url": "https://data.glygen.org/ln2downloads/pdb/current/AF-O19094-F1.pdb", "url_external": "https://alphafold.ebi.ac.uk/entry/O19094" } ], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "O19094", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/O19094" } ], "ann_type": "Motif_Annotation", "uniprotkb_annotation": "Microbody targeting signal", "eco_id": "ECO_0000255", "start_pos": 610, "end_pos": 612, "start_aa": "Pro", "end_aa": "Leu", "glycosite_overlap": [] } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [ { "ec_number": "2.3.1.137", "ec_name": "octanoyl-CoA + (R)-carnitine = O-octanoyl-(R)-carnitine + CoA.", "evidence": [ { "id": "2.3.1.137", "database": "Rhea", "url": "https://www.rhea-db.org/rhea/?query=ec:2.3.1.137" }, { "id": "2.3.1.137", "database": "BRENDA Enzymes", "url": "https://www.brenda-enzymes.org/enzyme.php?ecno=2.3.1.137" } ] } ], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" }, { "name": "homologset.oma", "label": "OMA Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 262, "end_pos": 264 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ], "tool_support": { "graph_view": "yes" } }, { "uniprot_canonical_ac": "Q3ZBK1-1", "uniprot_ac": "Q3ZBK1", "uniprot_id": "WDR89_BOVIN", "mass": { "chemical_mass": 42911.0, "monoisotopic_mass": 42911.0 }, "refseq": { "ac": "NP_001029830", "name": "WD repeat-containing protein 89", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001029830" }, "gene_names": [ { "name": "WDR89", "type": "recommended", "evidence": [ { "id": "Q3ZBK1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q3ZBK1" } ] }, { "name": "WDR89", "type": "synonym", "evidence": [ { "id": "NP_001029830", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001029830" } ] } ], "protein_names": [ { "name": "WD repeat-containing protein 89", "type": "recommended", "evidence": [ { "id": "Q3ZBK1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q3ZBK1/entry#names_and_taxonomy" } ] }, { "name": "WD repeat-containing protein 89", "type": "synonym", "evidence": [ { "id": "NP_001029830", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001029830" } ] } ], "function": [], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Bos taurus", "taxid": 9913, "evidence": [ { "database": "UniProtKB", "id": "Q3ZBK1", "url": "https://www.uniprot.org/uniprotkb/Q3ZBK1" } ], "common_name": "Bovine", "glygen_name": "Bovine", "reference_species": "Bos taurus [9913]" } ], "gene": [ { "name": "WDR89", "url": "https://www.uniprot.org/uniprotkb/Q3ZBK1", "locus": { "chromosome": "10", "start_pos": 75837036, "end_pos": 75886421, "strand": "+", "evidence": [ { "database": "Ensembl Gene", "id": "ENSBTAG00000008815", "url": "https://www.ensembl.org/id/ENSBTAG00000008815" } ] } } ], "crossref": [ { "id": "Q3ZBK1", "url": "https://alphafold.ebi.ac.uk/entry/Q3ZBK1", "database": "AlphaFoldDB", "categories": [] }, { "id": "ENSBTAG00000008815", "url": "https://bgee.org/?page=gene&gene_id=ENSBTAG00000008815", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "539045", "url": "https://www.ncbi.nlm.nih.gov/gene/539045", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR001680", "url": "https://www.ebi.ac.uk/interpro/entry/IPR001680", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR015943", "url": "https://www.ebi.ac.uk/interpro/entry/IPR015943", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR036322", "url": "https://www.ebi.ac.uk/interpro/entry/IPR036322", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR039328", "url": "https://www.ebi.ac.uk/interpro/entry/IPR039328", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "bta:539045", "url": "https://www.genome.jp/dbget-bin/www_bget?bta:539045", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "YHEKTDK", "url": "https://omabrowser.org/oma/group/YHEKTDK/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "Q3ZBK1", "url": "https://www.orthodb.org/?gene=Q3ZBK1", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR22889", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR22889", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR22889:SF0", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR22889:SF0", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00400", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00400", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "NP_001029830", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001029830", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0AAA9SH14", "url": "https://www.uniprot.org/uniprotkb/A0AAA9SH14", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0AAA9SH14-1", "url": "https://www.uniprot.org/uniprotkb/A0AAA9SH14-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0AAA9T013", "url": "https://www.uniprot.org/uniprotkb/A0AAA9T013", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0AAA9T013-1", "url": "https://www.uniprot.org/uniprotkb/A0AAA9T013-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0AAA9TDC2", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TDC2", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0AAA9TDC2-1", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TDC2-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0AAA9TSG8", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TSG8", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0AAA9TSG8-1", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TSG8-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0AAF6YSV5", "url": "https://www.uniprot.org/uniprotkb/A0AAF6YSV5", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0AAF6YSV5-1", "url": "https://www.uniprot.org/uniprotkb/A0AAF6YSV5-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "Q3ZBK1", "url": "https://www.uniprot.org/uniprotkb/Q3ZBK1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "Q3ZBK1-1", "url": "https://www.uniprot.org/uniprotkb/Q3ZBK1-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MEKIEEQFANLNIVKRSSETKEPTYLLGIDTSKTVQTEKGSLVAVLCSNGSIRIHDKERLNVIREFRGYPGLNGVKFANSHDSVYSSCTDGTVKCWDARLASGKPVQLFKGYPSNIFISFDISSNDHVICAGTEKVDDDALLVFWDARINSQDLSTTKEPLGAYSETHSDDITQVRFHPSNPNMVVSGSTDGLVNVFDISADNEDDALVTTCNSVSSVSFIGWSGKDYKQIYCMTHDEGFCWWDLNHLDTDEPITCLNVPDVREVINVKEGILDYLIGGLYHEKTDKLFVVGGTNTGIIRIMNCMTSGLVHVTSLQGGHAATVRSFCWNMQDDSLLTGGEDAQLLLWKPGAVEKTFTKKDSMKIASSVHQRVRVHSNDSYKRRKKQ", "length": 386, "header": "sp|Q3ZBK1-1|WDR89_BOVIN Isoform 1 of WD repeat-containing protein 89 OS=Bos taurus OX=9913 GN=WDR89 PE=2 SV=1 CANONICAL=Q3ZBK1-1" }, "isoforms": [ { "isoform_ac": "A0AAA9SH14-1", "url": "https://www.uniprot.org/uniprotkb/A0AAA9SH14/entry", "sequence": { "sequence": "MKKLRLTEIFTTLGCTPDMEKIEEQFANLNIVKRSSETKEPTYLLGIDTSKTVQTEKGSLVAVLCSNGSIRIHDKERLNVIREFRGYPGLNGVKFANSHDSVYSSCTDGTVKCWDARLASGKPVQLFKGYPSNIFISFDISSNDHVICAGTEKVDDDALLVFWDARINSQDLSTTKEPLGAYSETHSDDITQVRFHPSNPNMVVSGSTDGLVNVFDISADNEDDALVTTCNSVSSVSFIGWSGKDYKQIYCMTHDEGFCWWDLNHLDTDEPITCLNVPDVREVINVKEGILDYLIGGLYHEKTDKLFVVGGTNTGIIRIMNCMTSGLVHVTSLQGGHAATVRSFCWNMQDDSLLTGGEDAQLLLWKPGAVEKTFTKKDSMKIASSVHQRVRVHSNDSYKRRKKQ", "length": 404, "header": "tr|A0AAA9SH14-1|WDR89_BOVIN Computationally mapped isoform of WD repeat-containing protein 89 OS=Bos taurus OX=9913 GN=WDR89 PE=2 SV=1 CANONICAL=Q3ZBK1-1" }, "locus": { "chromosome": "10", "start_pos": 75849036, "end_pos": 75839210, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000105053.1", "url": "https://www.ensembl.org/id/ENSBTAT00000105053.1" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000082986.1", "url": "https://www.ensembl.org/id/ENSBTAP00000082986.1" } ] } }, { "isoform_ac": "A0AAA9T013-1", "url": "https://www.uniprot.org/uniprotkb/A0AAA9T013/entry", "sequence": { "sequence": "MEIHSSILAWKIPWTGEPRRIFTTLGCTPDMEKIEEQFANLNIVKRSSETKEPTYLLGIDTSKTVQTEKGSLVAVLCSNGSIRIHDKERLNVIREFRGYPGLNGVKFANSHDSVYSSCTDGTVKCWDARLASGKPVQLFKGYPSNIFISFDISSNDHVICAGTEKVDDDALLVFWDARINSQDLSTTKEPLGAYSETHSDDITQVRFHPSNPNMVVSGSTDGLVNVFDISADNEDDALVTTCNSVSSVSFIGWSGKDYKQIYCMTHDEGFCWWDLNHLDTDEPITCLNVPDVREVINVKEGILDYLIGGLYHEKTDKLFVVGGTNTGIIRIMNCMTSGLVHVTSLQGGHAATVRSFCWNMQDDSLLTGGEDAQLLLWKPGAVEKTFTKKDSMKIASSVHQRVRVHSNDSYKRRKKQ", "length": 416, "header": "tr|A0AAA9T013-1|WDR89_BOVIN Computationally mapped isoform of WD repeat-containing protein 89 OS=Bos taurus OX=9913 GN=WDR89 PE=2 SV=1 CANONICAL=Q3ZBK1-1" }, "locus": { "chromosome": "10", "start_pos": 75855559, "end_pos": 75839210, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000129378.1", "url": "https://www.ensembl.org/id/ENSBTAT00000129378.1" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000091016.1", "url": "https://www.ensembl.org/id/ENSBTAP00000091016.1" } ] } }, { "isoform_ac": "A0AAA9TDC2-1", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TDC2/entry", "sequence": { "sequence": "MPANLENSGVATGLEKIFTTLGCTPDMEKIEEQFANLNIVKRSSETKEPTYLLGIDTSKTVQTEKGSLVAVLCSNGSIRIHDKERLNVIREFRGYPGLNGVKFANSHDSVYSSCTDGTVKCWDARLASGKPVQLFKGYPSNIFISFDISSNDHVICAGTEKVDDDALLVFWDARINSQDLSTTKEPLGAYSETHSDDITQVRFHPSNPNMVVSGSTDGLVNVFDISADNEDDALVTTCNSVSSVSFIGWSGKDYKQIYCMTHDEGFCWWDLNHLDTDEPITCLNVPDVREVINVKEGILDYLIGGLYHEKTDKLFVVGGTNTGIIRIMNCMTSGLVHVTSLQGGHAATVRSFCWNMQDDSLLTGGEDAQLLLWKPGAVEKTFTKKDSMKIASSVHQRVRVHSNDSYKRRKKQ", "length": 412, "header": "tr|A0AAA9TDC2-1|WDR89_BOVIN Computationally mapped isoform of WD repeat-containing protein 89 OS=Bos taurus OX=9913 GN=WDR89 PE=2 SV=1 CANONICAL=Q3ZBK1-1" }, "locus": { "chromosome": "10", "start_pos": 75847311, "end_pos": 75839210, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000132960.1", "url": "https://www.ensembl.org/id/ENSBTAT00000132960.1" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000096636.1", "url": "https://www.ensembl.org/id/ENSBTAP00000096636.1" } ] } }, { "isoform_ac": "A0AAA9TSG8-1", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TSG8/entry", "sequence": { "sequence": "MCLFYKKWICNLTGDSEIFTTLGCTPDMEKIEEQFANLNIVKRSSETKEPTYLLGIDTSKTVQTEKGSLVAVLCSNGSIRIHDKERLNVIREFRGYPGLNGVKFANSHDSVYSSCTDGTVKCWDARLASGKPVQLFKGYPSNIFISFDISSNDHVICAGTEKVDDDALLVFWDARINSQDLSTTKEPLGAYSETHSDDITQVRFHPSNPNMVVSGSTDGLVNVFDISADNEDDALVTTCNSVSSVSFIGWSGKDYKQIYCMTHDEGFCWWDLNHLDTDEPITCLNVPDVREVINVKEGILDYLIGGLYHEKTDKLFVVGGTNTGIIRIMNCMTSGLVHVTSLQGGHAATVRSFCWNMQDDSLLTGGEDAQLLLWKPGAVEKTFTKKDSMKIASSVHQRVRVHSNDSYKRRKKQ", "length": 413, "header": "tr|A0AAA9TSG8-1|WDR89_BOVIN Computationally mapped isoform of WD repeat-containing protein 89 OS=Bos taurus OX=9913 GN=WDR89 PE=2 SV=1 CANONICAL=Q3ZBK1-1" }, "locus": { "chromosome": "10", "start_pos": 75863126, "end_pos": 75839210, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000124734.1", "url": "https://www.ensembl.org/id/ENSBTAT00000124734.1" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000101550.1", "url": "https://www.ensembl.org/id/ENSBTAP00000101550.1" } ] } }, { "isoform_ac": "A0AAF6YSV5-1", "url": "https://www.uniprot.org/uniprotkb/A0AAF6YSV5/entry", "sequence": { "sequence": "MHVSVFIEIEENKLVILGGERLCIFTTLGCTPDMEKIEEQFANLNIVKRSSETKEPTYLLGIDTSKTVQTEKGSLVAVLCSNGSIRIHDKERLNVIREFRGYPGLNGVKFANSHDSVYSSCTDGTVKCWDARLASGKPVQLFKGYPSNIFISFDISSNDHVICAGTEKVDDDALLVFWDARINSQDLSTTKEPLGAYSETHSDDITQVRFHPSNPNMVVSGSTDGLVNVFDISADNEDDALVTTCNSVSSVSFIGWSGKDYKQIYCMTHDEGFCWWDLNHLDTDEPITCLNVPDVREVINVKEGILDYLIGGLYHEKTDKLFVVGGTNTGIIRIMNCMTSGLVHVTSLQGGHAATVRSFCWNMQDDSLLTGGEDAQLLLWKPGAVEKTFTKKDSMKIASSVHQRVRVHSNDSYKRRKKQ", "length": 419, "header": "tr|A0AAF6YSV5-1|A0AAF6YSV5_BOVIN Computationally mapped isoform of WD repeat-containing protein 89 OS=Bos taurus OX=9913 GN=WDR89 PE=4 SV=1 CANONICAL=Q3ZBK1-1" }, "locus": { "chromosome": "10", "start_pos": 75841977, "end_pos": 75839210, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000011607.4", "url": "https://www.ensembl.org/id/ENSBTAT00000011607.4" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000011607.3", "url": "https://www.ensembl.org/id/ENSBTAP00000011607.3" } ] } }, { "isoform_ac": "Q3ZBK1-1", "url": "https://www.uniprot.org/uniprotkb/Q3ZBK1/entry#Q3ZBK1-1", "sequence": { "sequence": "MEKIEEQFANLNIVKRSSETKEPTYLLGIDTSKTVQTEKGSLVAVLCSNGSIRIHDKERLNVIREFRGYPGLNGVKFANSHDSVYSSCTDGTVKCWDARLASGKPVQLFKGYPSNIFISFDISSNDHVICAGTEKVDDDALLVFWDARINSQDLSTTKEPLGAYSETHSDDITQVRFHPSNPNMVVSGSTDGLVNVFDISADNEDDALVTTCNSVSSVSFIGWSGKDYKQIYCMTHDEGFCWWDLNHLDTDEPITCLNVPDVREVINVKEGILDYLIGGLYHEKTDKLFVVGGTNTGIIRIMNCMTSGLVHVTSLQGGHAATVRSFCWNMQDDSLLTGGEDAQLLLWKPGAVEKTFTKKDSMKIASSVHQRVRVHSNDSYKRRKKQ", "length": 386, "header": "sp|Q3ZBK1-1|WDR89_BOVIN Isoform 1 of WD repeat-containing protein 89 OS=Bos taurus OX=9913 GN=WDR89 PE=2 SV=1 CANONICAL=Q3ZBK1-1" }, "locus": { "chromosome": "10", "start_pos": 75840367, "end_pos": 75839210, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000096881.1", "url": "https://www.ensembl.org/id/ENSBTAT00000096881.1" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000087972.1", "url": "https://www.ensembl.org/id/ENSBTAP00000087972.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [ { "id": "bta:539045", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?bta:539045", "resource": "KEGG Pathway" } ], "orthologs": [ { "uniprot_canonical_ac": "A0A9J7G1K7-1", "protein_name": "WD repeat-containing protein 89", "gene_name": "Wdr89", "tax_id": 10029, "organism": "Cricetulus griseus", "sequence": { "sequence": "MDQSASASSMVLPNQGRRAEIRPAEGRAWFLSSSSVGIVAESFIPVDVAADMERIEEQFANLHIVKRSSEPKEPTYLLGIDTSKTVQAEKRSLVAVLCSNASIRIYDKETLNVLREFSGSPGLLNGVRFGNSCDNVYSASTDGTVKCWDARVASEKPMQLFKGYPSNSFISFDVNCKDHIISAGTEKVDDDALLVFWDARTASQDLSTRDPLGAYSETHSDDITQVRFHPSNPNMVVSGSTDGLVNVFDISVDNEDDALVATCNSISSVSCIGWSGRDYKQIYCMTHDEGFCWWDLNHLDTDEPITCLNIQDVREVTDGKEGHLDYLIGGLYHEKIDRLFVIGGTNTGKIHLMSCTSSGLTHVTSLQGGHAATVRSFCWNMPEDSLLTGGEDAQLLLWKPGAMQKTFTKKDSLKIASSVQQRVRVHSSDSYKRRKQQ", "length": 437 }, "evidence": [ { "id": "Q3ZBK1", "url": "https://omabrowser.org/oma/group/Q3ZBK1/", "database": "OMA" } ], "glygen_name": "Hamster", "common_name": "Chinese hamster" }, { "uniprot_canonical_ac": "F1SRR3-1", "protein_name": "WD repeat-containing protein 89", "gene_name": "WDR89", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MEKMEEQFANLNIVKRSSETKEPTYLLGIDTSKTISAEKGSLVAVLCSSGSIRIYDKERLNILREFRGYPGLNGVKFASSHDSVYSSCADGTVKCWDARLASNKPVQLFKGYPSNIFISFDISCNDHIICAGTEKVDDDALLVFWDARINSQGLSAPKDPLGAYSETHSDDITQVCFHPRDPNMVVSGSTDGLVNVFDISADNEEDALVTTCNSVSSVSSIGWSGKDYKQIYCMTHDEGFCWWDLNHLDTDEPITRLNIQDVRQVINVKEGVLDYLIGGLYHEKTDRLFVVGGTNQGIIHIMSCTASGLVHVTSLQGGHAATVRSFCWNMQDDSLLTGGEDAQLLLWKPGATEKTFTKKDSMKIASSVYQRVRVHSNDSYKRRKKQ", "length": 386 }, "evidence": [ { "id": "Q3ZBK1", "url": "https://omabrowser.org/oma/group/Q3ZBK1/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "Q5FVP5-1", "protein_name": "WD repeat-containing protein 89", "gene_name": "Wdr89", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MEKIKDQFANLHILRRSSEPKEPTYLLGIDTSKTVPAEKGGLVAVLCSNGSIRIYDKETLNLLREFSGSPGLLNGVRFANSCDNVYSASTDGTVKCWDARLASEKPAQLFKGYPSNIFISFDVNCKDHIICAGAEKVEDDALLVFWDARFTSQDLSTRDPLGAYSETHSDDITQVRFHPSNPNMVVSGSTDGLVNVFDLSVDNEEDALVATCNSVSSVSCIGWCGRDYKQIYCMTHDEGFCWWDLNHLDTDEPITCLNIQDVRDVTDVKEGHLDYLIGGLYHENMDRLFVIGGTNLGKIHLLSCTKTGLSHVTSLQGGHAATVRSFCWTVSEDSLLTGGEDAQLLLWKPGAVEKTFTKKDSLKIASSVQQRVRVHSSDSYKKRKQQ", "length": 386 }, "evidence": [ { "id": "Q3ZBK1", "url": "https://omabrowser.org/oma/group/Q3ZBK1/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "Q944S2-1", "protein_name": "WD repeat-containing protein GTS1", "gene_name": "GTS1", "tax_id": 3702, "organism": "Arabidopsis thaliana", "sequence": { "sequence": "MEEVSSEMEVEVQNRQLSDSSPAQNVKKFGLKNSIQTNFGSDYVFQIVPKIDWTAIAVSLSTNTVKLYSPVTGQYYGECKGHSDTVNQIAFSSDSAASPHVLHSCSSDGTIRSWDTRSFQQVSRIDTGNDQEIFSFSYGGAADNLLAGGCKEQVLLWDWRNSKQVACLEESHMDDVTQVHFVPNKPNKLLSASVDGLICLFNTEGDINDDDHLESVINVGTSIGKIGFLGDGYKKLWCLTHIETLSIWNWEDGSCEVNLEKARELASDSWTQDNVDYFVDCHCPGGEDLWVIGGTCAGTVGYFPVNYKQPGSIGTAEAILGGGHIDVVRSVLQMPGEYGGAAGLFGWTGGEDGRLCCWKSDEDATEINRSWTSSELVVKPPRNRKKNRHSPY", "length": 392 }, "evidence": [ { "id": "Q3ZBK1", "url": "https://omabrowser.org/oma/group/Q3ZBK1/", "database": "OMA" } ], "glygen_name": "Arabidopsis", "common_name": "Mouse-ear cress" }, { "uniprot_canonical_ac": "Q96FK6-1", "protein_name": "WD repeat-containing protein 89", "gene_name": "WDR89", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MEKIEEQFANLHIVKCSLGTKEPTYLLGIDTSKTVQAGKENLVAVLCSNGSIRIYDKERLNVLREFSGYPGLLNGVRFANSCDSVYSACTDGTVKCWDARVAREKPVQLFKGYPSNIFISFDINCNDHIICAGTEKVDDDALLVFWDARMNSQNLSTTKDSLGAYSETHSDDVTQVRFHPSNPNMVVSGSSDGLVNVFDINIDNEEDALVTTCNSISSVSCIGWSGKGYKQIYCMTHDEGFYWWDLNHLDTDEPVTRLNIQDVREVVNMKEDALDYLIGGLYHEKTDTLHVIGGTNKGRIHLMNCSMSGLTHVTSLQGGHAATVRSFCWNVQDDSLLTGGEDAQLLLWKPGAIEKTFTKKESMKIASSVHQRVRVHSNDSYKRRKKQ", "length": 387 }, "evidence": [ { "id": "Q3ZBK1", "url": "https://omabrowser.org/oma/group/Q3ZBK1/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "Q9D0R9-1", "protein_name": "WD repeat-containing protein 89", "gene_name": "Wdr89", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MEKIEDQFASLHIVRRSSEPKEPTYLLGIDTSKTVQADKGGLVAVLCSNGSIRIYDKETLHLLREFGGSPGLLSGVSFANSCDSVYSASTDGTVKCWDARGASEKPVQLFKGYPSCSFISFDVNCKDHVICAGAEKVDEDALLVFWDARFTSQDLSTRDPLGAYSETHSDDITQVRFHPSNPNLVVSGSTDGLVNVFDLSADKEEDALVATCNSVSSVSCIGWCGKDYKQIYCMTHDEGFCWWDLNHLDTDEPITCLNIQDVREITDVKDGHLDYLIGGLYHEKMDRLFVIGGTNTGKIHLLSCTSAGLTHVTSLHGGHAATVRSFCWNVSEDSLLTGGEDAQLLLWKPGAMEKTFTKKDSLKIASSVQQRVRVHSSDSYKKRKQQ", "length": 386 }, "evidence": [ { "id": "Q3ZBK1", "url": "https://omabrowser.org/oma/group/Q3ZBK1/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" } ], "go_annotation": {}, "pro_annotation": [], "site_annotation": [ { "start_pos": 377, "end_pos": 379, "annotation": "n_glycosylation_sequon" }, { "start_pos": 49, "end_pos": 51, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [ { "pdb_id": "AF-Q3ZBK1-F1", "pdb_chain": "global", "start_pos": 1, "end_pos": 386, "overlap": "1.0", "method": "AlphaFold", "type": "alphafold", "resolution": -1.0, "url": "https://data.glygen.org/ln2downloads/pdb/current/AF-Q3ZBK1-F1.pdb", "url_external": "https://alphafold.ebi.ac.uk/entry/Q3ZBK1" } ], "lectin_list": [], "domain_list": [], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" }, { "name": "homologset.oma", "label": "OMA Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 377, "end_pos": 379 }, { "start_pos": 49, "end_pos": 51 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ], "tool_support": { "graph_view": "yes" } }, { "uniprot_canonical_ac": "Q2T9U9-1", "uniprot_ac": "Q2T9U9", "uniprot_id": "CC160_BOVIN", "mass": { "chemical_mass": 37695.0, "monoisotopic_mass": 37695.0 }, "refseq": { "ac": "NP_001181989", "name": "coiled-coil domain-containing protein 160", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001181989" }, "gene_names": [ { "name": "CCDC160", "type": "recommended", "evidence": [ { "id": "Q2T9U9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q2T9U9" } ] }, { "name": "CCDC160", "type": "synonym", "evidence": [ { "id": "NP_001181989", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001181989" } ] } ], "protein_names": [ { "name": "Coiled-coil domain-containing protein 160", "type": "recommended", "evidence": [ { "id": "Q2T9U9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q2T9U9/entry#names_and_taxonomy" } ] }, { "name": "coiled-coil domain-containing protein 160", "type": "synonym", "evidence": [ { "id": "NP_001181989", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001181989" } ] } ], "function": [], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Bos taurus", "taxid": 9913, "evidence": [ { "database": "UniProtKB", "id": "Q2T9U9", "url": "https://www.uniprot.org/uniprotkb/Q2T9U9" } ], "common_name": "Bovine", "glygen_name": "Bovine", "reference_species": "Bos taurus [9913]" } ], "gene": [ { "name": "CCDC160", "url": "https://www.uniprot.org/uniprotkb/Q2T9U9", "locus": { "chromosome": "X", "start_pos": 18029325, "end_pos": 18020519, "strand": "-", "evidence": [ { "database": "Ensembl Gene", "id": "ENSBTAG00000036349", "url": "https://www.ensembl.org/id/ENSBTAG00000036349" } ] } } ], "crossref": [ { "id": "Q2T9U9", "url": "https://alphafold.ebi.ac.uk/entry/Q2T9U9", "database": "AlphaFoldDB", "categories": [] }, { "id": "ENSBTAG00000036349", "url": "https://bgee.org/?page=gene&gene_id=ENSBTAG00000036349", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "767883", "url": "https://www.ncbi.nlm.nih.gov/gene/767883", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "bta:767883", "url": "https://www.genome.jp/dbget-bin/www_bget?bta:767883", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "STWTTKE", "url": "https://omabrowser.org/oma/group/STWTTKE/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "PTHR48251", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR48251", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR48251:SF1", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR48251:SF1", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "NP_001181989", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001181989", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0AAA9SJY8", "url": "https://www.uniprot.org/uniprotkb/A0AAA9SJY8", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0AAA9SJY8-1", "url": "https://www.uniprot.org/uniprotkb/A0AAA9SJY8-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "Q2T9U9", "url": "https://www.uniprot.org/uniprotkb/Q2T9U9", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "Q2T9U9-1", "url": "https://www.uniprot.org/uniprotkb/Q2T9U9-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MDARRKHWKENKFAPLFSAQDIPNEAAQLESSSEQMPLDKVKRMEIIFNLSSRKFREENKFKRKEFISQPNENEQESNLIERKINISKTEADTNSVSCESSNLDIATEESFNSTEELPTWVIKELSTPPQKDKKKKFTEGMSSKLRLNLLNEELEVLDMKCKKIEEEFESAEKELLNSKKEVSTKPLNFQEAEVETSKTDWELQALRNDLSEKATNVKNLTEELQQAKEVIHKLSLENKDLKETVRKLKRQTEVGNAFLKEEMKLYYELEMEKIRGELTAIKNELRTEKSLQARNNRALELLRKHFASVMPSGTSDNFMGDFF", "length": 323, "header": "sp|Q2T9U9-1|CC160_BOVIN Isoform 1 of Coiled-coil domain-containing protein 160 OS=Bos taurus OX=9913 GN=CCDC160 PE=2 SV=2 CANONICAL=Q2T9U9-1" }, "isoforms": [ { "isoform_ac": "A0AAA9SJY8-1", "url": "https://www.uniprot.org/uniprotkb/A0AAA9SJY8/entry", "sequence": { "sequence": "MLQWQILELEEVPEEMDARRKHWKENKFAPLFSAQDIPNEAAQLESSSEQMPLDKVKRMEIIFNLSSRKFREENKFKRKEFISQPNENEQESNLIERKINISKTEADTNSVSCESSNLDIATEESFNSTEELPTWVIKELSTPPQKDKKKKFTEGMSSKLRLNLLNEELEVLDMKCKKIEEEFESAEKELLNSKKEVSTKPLNFQEAEVETSKTDWELQALRNDLSEKATNVKNLTEELQQAKEVIHKLSLENKDLKETVRKLKRQTEVGNAFLKEEMKLYYELEMEKIRGELTAIKNELRTEKSLQARNNRALELLRKHFASVMPSGTSDNFMGDFF", "length": 338, "header": "tr|A0AAA9SJY8-1|CC160_BOVIN Computationally mapped isoform of Coiled-coil domain-containing protein 160 OS=Bos taurus OX=9913 GN=CCDC160 PE=2 SV=1 CANONICAL=Q2T9U9-1" }, "locus": { "chromosome": "X", "start_pos": 18029050, "end_pos": 18026407, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000129863.1", "url": "https://www.ensembl.org/id/ENSBTAT00000129863.1" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000085630.1", "url": "https://www.ensembl.org/id/ENSBTAP00000085630.1" } ] } }, { "isoform_ac": "Q2T9U9-1", "url": "https://www.uniprot.org/uniprotkb/Q2T9U9/entry#Q2T9U9-1", "sequence": { "sequence": "MDARRKHWKENKFAPLFSAQDIPNEAAQLESSSEQMPLDKVKRMEIIFNLSSRKFREENKFKRKEFISQPNENEQESNLIERKINISKTEADTNSVSCESSNLDIATEESFNSTEELPTWVIKELSTPPQKDKKKKFTEGMSSKLRLNLLNEELEVLDMKCKKIEEEFESAEKELLNSKKEVSTKPLNFQEAEVETSKTDWELQALRNDLSEKATNVKNLTEELQQAKEVIHKLSLENKDLKETVRKLKRQTEVGNAFLKEEMKLYYELEMEKIRGELTAIKNELRTEKSLQARNNRALELLRKHFASVMPSGTSDNFMGDFF", "length": 323, "header": "sp|Q2T9U9-1|CC160_BOVIN Isoform 1 of Coiled-coil domain-containing protein 160 OS=Bos taurus OX=9913 GN=CCDC160 PE=2 SV=2 CANONICAL=Q2T9U9-1" }, "locus": { "chromosome": "X", "start_pos": 18029050, "end_pos": 18028082, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000050851.4", "url": "https://www.ensembl.org/id/ENSBTAT00000050851.4" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000047500.2", "url": "https://www.ensembl.org/id/ENSBTAP00000047500.2" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [ { "id": "bta:767883", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?bta:767883", "resource": "KEGG Pathway" } ], "orthologs": [ { "uniprot_canonical_ac": "A0A8I5ZZY1-1", "protein_name": "Coiled-coil domain containing 160", "gene_name": "Ccdc160", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MDARRKQWKDNTFTPFVNEHDFQEDAAPPQSFSEQPAADKPKRMGRISNFSMRNNQEGNKFKRKEYSSQIVEREQDPNLRERRKNVSKNEANTNVAFRDLLDSDEATKESSHRRESASAWSKKELPAATQGTRKKWTEAMPPKLRLHLLNEELGELSLKCREIEQDFENAEKELLNSRKEASMKAVNFQEPIAASKKDRELQALKNDLSEKATNVKNLTEELQQAKEVMYRLNLENRNLKDAVRKLKHQTELNTALLREEMKLFYELEMEKIRLELGAIKNELRVEKTLRAKNSRALQLLGRHVASVVRSSNTADHFTGNVF", "length": 322 }, "evidence": [ { "id": "Q2T9U9", "url": "https://omabrowser.org/oma/group/Q2T9U9/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "A6NGH7-1", "protein_name": "Coiled-coil domain-containing protein 160", "gene_name": "CCDC160", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MDARRKHWKENMFTPFFSAQDVLEETSEPESSSEQTTADSSKGMEEIYNLSSRKFQEESKFKRKKYIFQLNEIEQEQNLRENKRNISKNETDTNSASYESSNVDVTTEESFNSTEDNSTCSTDNLPALLRQDIRKKFMERMSPKLCLNLLNEELEELNMKYRKIEEEFENAEKELLHYKKEIFTKPLNFQETETDASKSDYELQALRNDLSEKATNVKNLSEQLQQAKEVIHKLNLENRNLKEAVRKLKHQTEVGNVLLKEEMKSYYELEMAKIRGELSVIKNELRTEKTLQARNNRALELLRKYYASSMVTSSSILDHFTGDFF", "length": 325 }, "evidence": [ { "id": "Q2T9U9", "url": "https://omabrowser.org/oma/group/Q2T9U9/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "K7GLA1-1", "protein_name": "Coiled-coil domain containing 160", "gene_name": "CCDC160", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MDARSKHWKENMFAPFFSAQDILDEASQLESSAEQLTLDKLKRMERIFNLSSRKFQDANKSKRKELISQLNENEQEPNLRERKINISKNKAITNSASCESSNVEVPTKESFNSTKETPTWGTKEVVTPWRKDKKKKLTKGMSPKLRLNLLNDELEVLNMKCRKIEEEFENAEKELLNSKKGVSAKPLNFQEAGVETSKKDWELQALRNDLSEKTTNVKNLTEELEQAKEVIRKLSLENKDLKEAVRKLKRQTEVGHALLKEEMKLYYELEMEKVRGELNAIKNELRAEKTLQARNNRALELLRKHFASVTSNTPDSFMEDFFKT", "length": 324 }, "evidence": [ { "id": "Q2T9U9", "url": "https://omabrowser.org/oma/group/Q2T9U9/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "Q3UYG1-1", "protein_name": "Coiled-coil domain-containing protein 160", "gene_name": "Ccdc160", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MDARRKHWKDNTFTPFLNEHDFQEAAAPPQPLSEQSSADNHKRMGRVSNFSVRNTQEGNKFKRKDYSSQIAEGEQDSNLRERRMNVSKNDANTNSAFWDSLHLDDATKESSHRRESASAWNKKKLPAATQVTRKKWTEAMPPKLRLHLLNEELGELSLKCREIERDFENAEKELLNFRKEASVKAVNFQEPGTGASKKDRELQALKNDLSEKATNVKNLTEELQQAKEVMYRLSLENRNLKDAVRKLKHQTELNTALLREEMKLFYELEMEKIRLELGAIKNELRVEKTLRVKNSRALEVLGRHVASVVRSSNPADHFTGNIF", "length": 323 }, "evidence": [ { "id": "Q2T9U9", "url": "https://omabrowser.org/oma/group/Q2T9U9/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" } ], "go_annotation": {}, "pro_annotation": [], "site_annotation": [ { "start_pos": 112, "end_pos": 114, "annotation": "n_glycosylation_sequon" }, { "start_pos": 219, "end_pos": 221, "annotation": "n_glycosylation_sequon" }, { "start_pos": 49, "end_pos": 51, "annotation": "n_glycosylation_sequon" }, { "start_pos": 85, "end_pos": 87, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [ { "pdb_id": "AF-Q2T9U9-F1", "pdb_chain": "global", "start_pos": 1, "end_pos": 323, "overlap": "1.0", "method": "AlphaFold", "type": "alphafold", "resolution": -1.0, "url": "https://data.glygen.org/ln2downloads/pdb/current/AF-Q2T9U9-F1.pdb", "url_external": "https://alphafold.ebi.ac.uk/entry/Q2T9U9" } ], "lectin_list": [], "domain_list": [], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" }, { "name": "homologset.oma", "label": "OMA Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 112, "end_pos": 114 }, { "start_pos": 219, "end_pos": 221 }, { "start_pos": 49, "end_pos": 51 }, { "start_pos": 85, "end_pos": 87 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { 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"yes" } }, { "uniprot_canonical_ac": "P19035-1", "uniprot_ac": "P19035", "uniprot_id": "APOC3_BOVIN", "mass": { "chemical_mass": 10692.0, "monoisotopic_mass": 10692.0 }, "refseq": { "ac": "NP_001001175", "name": "apolipoprotein C-III precursor", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001001175" }, "gene_names": [ { "name": "APOC3", "type": "recommended", "evidence": [ { "id": "P19035", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P19035" } ] }, { "name": "APOC3", "type": "synonym", "evidence": [ { "id": "NP_001001175", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001001175" } ] } ], "protein_names": [ { "name": "Apolipoprotein C-III", "type": "recommended", "evidence": [ { "id": "P19035", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P19035/entry#names_and_taxonomy" } ] }, { "name": "Apo-CIII", "type": "synonym", "evidence": [ { "id": "P19035", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P19035/entry#names_and_taxonomy" } ] }, { "name": "ApoC-III", "type": "synonym", "evidence": [ { "id": "P19035", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P19035/entry#names_and_taxonomy" } ] }, { "name": "Apolipoprotein C3", "type": "synonym", "evidence": [ { "id": "P19035", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P19035/entry#names_and_taxonomy" } ] }, { "name": "apo-CIII", "type": "synonym", "evidence": [ { "id": "NP_001001175", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001001175" } ] }, { "name": "apoC-III", "type": "synonym", "evidence": [ { "id": "NP_001001175", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001001175" } ] }, { "name": "apolipoprotein C-III precursor", "type": "synonym", "evidence": [ { "id": "NP_001001175", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001001175" } ] }, { "name": "apolipoprotein C-III", "type": "synonym", "evidence": [ { "id": "NP_001001175", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001001175" } ] } ], "function": [ { "annotation": "ApoC-I and apoC-III inhibit lipolysis by displacing LPL from lipid emulsion particles. We also propose a role for these apolipoproteins in the irreversible inactivation of LPL by factors such as angptl4.", "evidence": [ { "database": "RefSeq", "id": "NP_001001175", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001001175" }, { "database": "PubMed", "id": "24121499", "url": "https://glygen.org/publication/PubMed/24121499" } ] }, { "annotation": "Component of triglyceride-rich very low density lipoproteins (VLDL) and high density lipoproteins (HDL) in plasma. Plays a multifaceted role in triglyceride homeostasis. Intracellularly, promotes hepatic very low density lipoprotein 1 (VLDL1) assembly and secretion; extracellularly, attenuates hydrolysis and clearance of triglyceride-rich lipoproteins (TRLs). Impairs the lipolysis of TRLs by inhibiting lipoprotein lipase and the hepatic uptake of TRLs by remnant receptors. Formed of several curved helices connected via semiflexible hinges, so that it can wrap tightly around the curved micelle surface and easily adapt to the different diameters of its natural binding partners.", "evidence": [ { "database": "UniProtKB", "id": "P19035", "url": "https://www.uniprot.org/uniprotkb/P19035#function" }, { "database": "UniProtKB", "id": "P02656", "url": "https://www.uniprot.org/uniprotkb/P02656#function" }, { "database": "UniProtKB", "id": "A0AAF6YXN2", "url": "https://www.uniprot.org/uniprotkb/A0AAF6YXN2#function" }, { "database": "UniProtKB", "id": "ARBA00045699", "url": "https://www.uniprot.org/uniprotkb/ARBA00045699#function" }, { "database": "UniProtKB", "id": "A0AAA9SNX5", "url": "https://www.uniprot.org/uniprotkb/A0AAA9SNX5#function" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Bos taurus", "taxid": 9913, "evidence": [ { "database": "UniProtKB", "id": "P19035", "url": "https://www.uniprot.org/uniprotkb/P19035" } ], "common_name": "Bovine", "glygen_name": "Bovine", "reference_species": "Bos taurus [9913]" } ], "gene": [ { "name": "APOC3", "url": "https://www.uniprot.org/uniprotkb/P19035", "locus": { "chromosome": "15", "start_pos": 27502193, "end_pos": 27483224, "strand": "-", "evidence": [ { "database": "Ensembl Gene", "id": "ENSBTAG00000012398", "url": "https://www.ensembl.org/id/ENSBTAG00000012398" } ] } } ], "crossref": [ { "id": "P19035", "url": "https://alphafold.ebi.ac.uk/entry/P19035", "database": "AlphaFoldDB", "categories": [] }, { "id": "ENSBTAG00000012398", "url": "https://bgee.org/?page=gene&gene_id=ENSBTAG00000012398", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "408009", "url": "https://www.ncbi.nlm.nih.gov/gene/408009", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "143771", "url": "https://www.iedb.org/epitope/143771", "database": "IEDB", "categories": [ "Other" ] }, { "id": "IPR008403", "url": "https://www.ebi.ac.uk/interpro/entry/IPR008403", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR038195", "url": "https://www.ebi.ac.uk/interpro/entry/IPR038195", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "bta:408009", "url": "https://www.genome.jp/dbget-bin/www_bget?bta:408009", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "YWSTFKG", "url": "https://omabrowser.org/oma/group/YWSTFKG/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "P19035", "url": "https://www.orthodb.org/?gene=P19035", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR14225", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR14225", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR14225:SF0", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR14225:SF0", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF05778", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF05778", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PR:P19035", "url": "https://proconsortium.org/cgi-bin/entry_pro?id=PR:P19035", "database": "PRO", "categories": [ "Protein" ] }, { "id": "R-BTA-8963888", "url": "https://www.reactome.org/PathwayBrowser/#R-BTA-8963888", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "R-BTA-8963901", "url": "https://www.reactome.org/PathwayBrowser/#R-BTA-8963901", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "R-BTA-8964058", "url": "https://www.reactome.org/PathwayBrowser/#R-BTA-8964058", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "R-BTA-975634", "url": "https://www.reactome.org/PathwayBrowser/#R-BTA-975634", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "NP_001001175", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001001175", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0AAA9SNX5", "url": "https://www.uniprot.org/uniprotkb/A0AAA9SNX5", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0AAA9SNX5-1", "url": "https://www.uniprot.org/uniprotkb/A0AAA9SNX5-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0AAF6YXN2", "url": "https://www.uniprot.org/uniprotkb/A0AAF6YXN2", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0AAF6YXN2-1", "url": "https://www.uniprot.org/uniprotkb/A0AAF6YXN2-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "P19035", "url": "https://www.uniprot.org/uniprotkb/P19035", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "P19035-1", "url": "https://www.uniprot.org/uniprotkb/P19035-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MQPRLLLLAAFLALLVLPEATKAEEGSLLDKMQGYVKEATKTAKDALSSVQESQVAQQARDWMTESFSSLKDYWSSFKGKFTDFWESATSPTQSPP", "length": 96, "header": "sp|P19035-1|APOC3_BOVIN Isoform 1 of Apolipoprotein C-III OS=Bos taurus OX=9913 GN=APOC3 PE=1 SV=2 CANONICAL=P19035-1" }, "isoforms": [ { "isoform_ac": "A0AAA9SNX5-1", "url": "https://www.uniprot.org/uniprotkb/A0AAA9SNX5/entry", "sequence": { "sequence": "MQPRLLLLAAFLALLVLPEATKAEEGSLLDKMQGYVKEATKTAKDALSSVQESQVAQQARDWMTESFSSLKDYWSSFKGKFTDFWESATTTAKDVVQKTRDWMTESFSSLKDYWSSFKGKFT", "length": 122, "header": "tr|A0AAA9SNX5-1|APOC3_BOVIN Computationally mapped isoform of Apolipoprotein C-III OS=Bos taurus OX=9913 GN=APOC3 PE=1 SV=1 CANONICAL=P19035-1" }, "locus": { "chromosome": "15", "start_pos": 27501189, "end_pos": 27486689, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000096546.2", "url": "https://www.ensembl.org/id/ENSBTAT00000096546.2" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000087069.1", "url": "https://www.ensembl.org/id/ENSBTAP00000087069.1" } ] } }, { "isoform_ac": "A0AAF6YXN2-1", "url": "https://www.uniprot.org/uniprotkb/A0AAF6YXN2/entry", "sequence": { "sequence": "MQPRLLLLAAFLALLVLPATKAEEGSLLDKMQGYVKEATKTAKDALSSVQESQVAQQARDWMTESFSSLKDYWSSFKGKFTDFWESATSPTQSPP", "length": 95, "header": "tr|A0AAF6YXN2-1|A0AAF6YXN2_BOVIN Computationally mapped isoform of Apolipoprotein C-III OS=Bos taurus OX=9913 GN=APOC3 PE=1 SV=1 CANONICAL=P19035-1" }, "locus": { "chromosome": "15", "start_pos": 27488433, "end_pos": 27486689, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000016453.6", "url": "https://www.ensembl.org/id/ENSBTAT00000016453.6" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000016453.5", "url": "https://www.ensembl.org/id/ENSBTAP00000016453.5" } ] } }, { "isoform_ac": "P19035-1", "url": "https://www.uniprot.org/uniprotkb/P19035/entry#P19035-1", "sequence": { "sequence": "MQPRLLLLAAFLALLVLPEATKAEEGSLLDKMQGYVKEATKTAKDALSSVQESQVAQQARDWMTESFSSLKDYWSSFKGKFTDFWESATSPTQSPP", "length": 96, "header": "sp|P19035-1|APOC3_BOVIN Isoform 1 of Apolipoprotein C-III OS=Bos taurus OX=9913 GN=APOC3 PE=1 SV=2 CANONICAL=P19035-1" }, "locus": { "chromosome": "15", "start_pos": 27488433, "end_pos": 27486689, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000136158.1", "url": "https://www.ensembl.org/id/ENSBTAT00000136158.1" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000105584.1", "url": "https://www.ensembl.org/id/ENSBTAP00000105584.1" } ] } } ], "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "O-GalNAcylation", "prediction_tool_list": [], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "T", "relation": "attached", "comment": "O-linked (GalNAc...) threonine;O-GalNAcylation", "icn3d_view": {}, "start_pos": 92, "start_aa": "Thr", "end_pos": 92, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr92", "evidence": [ { "id": "P19035", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P19035#ptm_processing" } ], "filter_code": "000000000000000010000.00000010000000.0.01000" } ], "phosphorylation": [], "glycation": [], "keywords": [ "glycoprotein", "glycoprotein_predicted" ], "publication": [ { "title": "I-Ep-bound self-peptides: identification, characterization, and role in alloreactivity.", "journal": "Journal of immunology (Baltimore, Md. : 1950)", "date": "2006-01-15", "authors": "Felix Nathan J, Suri Anish, Walters James J, Horvath Stephen, Gross Michael L, Allen Paul M", "evidence": [ { "database": "IEDB", "id": "143771", "url": "https://www.iedb.org/epitope/143771" } ], "reference": [ { "type": "PubMed", "id": "16393994", "url": "https://glygen.org/publication/PubMed/16393994" } ] }, { "title": "Primary structure of the bovine analogues to human apolipoproteins CII and CIII. Studies on isoforms and evidence for proteolytic processing.", "journal": "Eur. J. Biochem.", "date": "1990", "authors": "Bengtsson-Olivecrona G, Sletten K", "evidence": [ { "database": "UniProtKB", "id": "P19035", "url": "https://www.uniprot.org/uniprotkb/P19035" } ], "reference": [ { "type": "PubMed", "id": "2209608", "url": "https://glygen.org/publication/PubMed/2209608" } ] }, { "title": "Apolipoproteins C-I and C-III inhibit lipoprotein lipase activity by displacement of the enzyme from lipid droplets.", "journal": "The Journal of biological chemistry", "date": "2013-11-22", "authors": "Larsson Mikael, Vorrsj\u00f6 Evelina, Talmud Philippa, Lookene Aivar, Olivecrona Gunilla", "evidence": [ { "database": "RefSeq", "id": "NP_001001175", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001001175" } ], "reference": [ { "type": "PubMed", "id": "24121499", "url": "https://glygen.org/publication/PubMed/24121499" } ] } ], "pathway": [ { "id": "bta:408009", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?bta:408009", "resource": "KEGG Pathway" }, { "id": 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"uniprot_canonical_ac": "Q0II74-1", "uniprot_ac": "Q0II74", "uniprot_id": "TM253_BOVIN", "mass": { "chemical_mass": 18153.0, "monoisotopic_mass": 18153.0 }, "refseq": { "ac": "NP_001069196", "name": "transmembrane protein 253", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001069196" }, "gene_names": [ { "name": "TMEM253", "type": "recommended", "evidence": [ { "id": "Q0II74", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q0II74" } ] }, { "name": "C10H14orf176", "type": "synonym", "evidence": [ { "id": "NP_001069196", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001069196" } ] }, { "name": "TMEM253", "type": "synonym", "evidence": [ { "id": "NP_001069196", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001069196" } ] } ], "protein_names": [ { "name": "Transmembrane protein 253", "type": "recommended", "evidence": [ { "id": "Q0II74", "database": "UniProtKB", "url": 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"+", "evidence": [ { "database": "Ensembl Gene", "id": "ENSBTAG00000032908", "url": "https://www.ensembl.org/id/ENSBTAG00000032908" } ] } } ], "crossref": [ { "id": "Q0II74", "url": "https://alphafold.ebi.ac.uk/entry/Q0II74", "database": "AlphaFoldDB", "categories": [] }, { "id": "ENSBTAG00000032908", "url": "https://bgee.org/?page=gene&gene_id=ENSBTAG00000032908", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "515865", "url": "https://www.ncbi.nlm.nih.gov/gene/515865", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR038874", "url": "https://www.ebi.ac.uk/interpro/entry/IPR038874", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "bta:515865", "url": "https://www.genome.jp/dbget-bin/www_bget?bta:515865", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "PRLWKVQ", "url": "https://omabrowser.org/oma/group/PRLWKVQ/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "Q0II74", "url": "https://www.orthodb.org/?gene=Q0II74", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR37359", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR37359", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR37359:SF1", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR37359:SF1", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "NP_001069196", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001069196", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0AAA9SSV8", "url": "https://www.uniprot.org/uniprotkb/A0AAA9SSV8", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0AAA9SSV8-1", "url": "https://www.uniprot.org/uniprotkb/A0AAA9SSV8-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0AAA9SVF9", "url": "https://www.uniprot.org/uniprotkb/A0AAA9SVF9", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0AAA9SVF9-1", "url": "https://www.uniprot.org/uniprotkb/A0AAA9SVF9-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "Q0II74", "url": "https://www.uniprot.org/uniprotkb/Q0II74", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "Q0II74-1", "url": "https://www.uniprot.org/uniprotkb/Q0II74-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MEDRAGQQERPSLRLEKLQHWARHRQSGRLLVLAVSQLWLAVAVVPFAVSVACLNSACHMTTALPLGPGILGLLTGIVTLELRRAPRLWKLAGLLVLELSAEAFTLGGVLVSAYSLFLLSQRKPRCCRSQSLRYQELQEGLSELEEVPELETGPTVASTAKRTNQ", "length": 165, "header": "sp|Q0II74-1|TM253_BOVIN Isoform 1 of Transmembrane protein 253 OS=Bos taurus OX=9913 GN=TMEM253 PE=2 SV=1 CANONICAL=Q0II74-1" }, "isoforms": [ { "isoform_ac": "A0AAA9SSV8-1", "url": "https://www.uniprot.org/uniprotkb/A0AAA9SSV8/entry", "sequence": { "sequence": 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"MEDRAGQQERPSLRLEKLQHWARHRQSGRLLVLAVSQLWLAVAVVPFAVSVACLNSACHMTTALPLGPGILGLLTGIVTLELRRAPRLWKVRAMMIFNTFNLISGFIALVVEVMKTALMSAPTVPSEGLSELEEVPELETGPTVASTAKRTNQ", "length": 153, "header": "tr|A0AAA9SVF9-1|TM253_BOVIN Computationally mapped isoform of Transmembrane protein 253 OS=Bos taurus OX=9913 GN=TMEM253 PE=2 SV=1 CANONICAL=Q0II74-1" }, "locus": { "chromosome": "10", "start_pos": 25990397, "end_pos": 25988363, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000097893.1", "url": "https://www.ensembl.org/id/ENSBTAT00000097893.1" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000090452.1", "url": "https://www.ensembl.org/id/ENSBTAP00000090452.1" } ] } }, { "isoform_ac": "Q0II74-1", "url": "https://www.uniprot.org/uniprotkb/Q0II74/entry#Q0II74-1", "sequence": { "sequence": "MEDRAGQQERPSLRLEKLQHWARHRQSGRLLVLAVSQLWLAVAVVPFAVSVACLNSACHMTTALPLGPGILGLLTGIVTLELRRAPRLWKLAGLLVLELSAEAFTLGGVLVSAYSLFLLSQRKPRCCRSQSLRYQELQEGLSELEEVPELETGPTVASTAKRTNQ", "length": 165, "header": "sp|Q0II74-1|TM253_BOVIN Isoform 1 of Transmembrane protein 253 OS=Bos taurus OX=9913 GN=TMEM253 PE=2 SV=1 CANONICAL=Q0II74-1" }, "locus": { "chromosome": "10", "start_pos": 25990397, "end_pos": 25988363, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000055545.2", "url": "https://www.ensembl.org/id/ENSBTAT00000055545.2" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000051437.1", "url": "https://www.ensembl.org/id/ENSBTAP00000051437.1" } ] } } ], "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "other", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 155, "start_aa": "Thr", "end_pos": 155, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr155", "evidence": [ { "id": "", "database": "GlyGen", "url": "https://data.glygen.org/" } ], "filter_code": "000000000000000010000.00000000001000.0.01000" } ], "phosphorylation": [], "glycation": [], "keywords": [ "glycoprotein", "glycoprotein_predicted" ], "publication": [], "pathway": [ { "id": "bta:515865", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?bta:515865", "resource": "KEGG Pathway" } ], "orthologs": [ { "uniprot_canonical_ac": "D4ACQ1-1", "protein_name": "Transmembrane protein 253", "gene_name": "Tmem253", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MDQNVDQPRQEEPSLRLEKLQHWAKRRHSGHLLVLAVSQLWLAIAVVPFTLSVSCLNSACHLATVLPLWPGASGLLTGIVTLEFRRAPCIWKVRAMMISNTLNLILGFIAVVMEVIKTALGTASADSSQSTGLLVLELSAEAFTLGGVLFSTYALFLLSQRKPGSFKKSRLQYQELQEGLSEVEEVSGLENDPVVASTGNRTEE", "length": 204 }, "evidence": [ { "id": "Q0II74", "url": "https://omabrowser.org/oma/group/Q0II74/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "P0C7T8-1", "protein_name": "Transmembrane 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"S10A8_BOVIN", "mass": { "chemical_mass": 10460.0, "monoisotopic_mass": 10460.0 }, "refseq": { "ac": "NP_001107197", "name": "protein S100-A8", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001107197" }, "gene_names": [ { "name": "S100A8", "type": "recommended", "evidence": [ { "id": "P28782", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P28782" } ] }, { "name": "S100A8", "type": "synonym", "evidence": [ { "id": "NP_001107197", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001107197" } ] } ], "protein_names": [ { "name": "Protein S100-A8", "type": "recommended", "evidence": [ { "id": "P28782", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P28782/entry#names_and_taxonomy" } ] }, { "name": "BEE11", "type": "synonym", "evidence": [ { "id": "NP_001107197", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001107197" }, { "id": "P28782", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P28782/entry#names_and_taxonomy" } ] }, { "name": "Calgranulin-A", "type": "synonym", "evidence": [ { "id": "P28782", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P28782/entry#names_and_taxonomy" } ] }, { "name": "Neutrophil cytosolic 7 kDa protein", "type": "synonym", "evidence": [ { "id": "P28782", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P28782/entry#names_and_taxonomy" } ] }, { "name": "P7", "type": "synonym", "evidence": [ { "id": "NP_001107197", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001107197" }, { "id": "P28782", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P28782/entry#names_and_taxonomy" } ] }, { "name": "S100 calcium-binding protein A8", "type": "synonym", "evidence": [ { "id": "P28782", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P28782/entry#names_and_taxonomy" } ] }, { "name": "calgranulin-A", "type": "synonym", "evidence": [ { "id": "NP_001107197", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001107197" } ] }, { "name": "neutrophil cytosolic 7 kDa protein", "type": "synonym", "evidence": [ { "id": "NP_001107197", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001107197" } ] }, { "name": "protein S100-A8", "type": "synonym", "evidence": [ { "id": "NP_001107197", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001107197" } ] } ], "function": [ { "annotation": "Data suggest that up-regulation of S100A8 and S100A9 is a key component of early endometrial response to uterine involution in the post-partum period and to prevent chronic endometritis/uterine inflammation; up-regulation can be influenced by diet. Publication Status: Online-Only", "evidence": [ { "database": "RefSeq", "id": "NP_001107197", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001107197" }, { "database": "PubMed", "id": "23533291", "url": "https://glygen.org/publication/PubMed/23533291" } ] }, { "annotation": "S100A8 is a calcium- and zinc-binding protein which plays a prominent role in the regulation of inflammatory processes and immune response. It can induce neutrophil chemotaxis and adhesion. Predominantly found as calprotectin (S100A8/A9) which has a wide plethora of intra- and extracellular functions. The intracellular functions include: facilitating leukocyte arachidonic acid trafficking and metabolism, modulation of the tubulin-dependent cytoskeleton during migration of phagocytes and activation of the neutrophilic NADPH-oxidase. Also participates in regulatory T-cell differentiation together with CD69. Activates NADPH-oxidase by facilitating the enzyme complex assembly at the cell membrane, transferring arachidonic acid, an essential cofactor, to the enzyme complex and S100A8 contributes to the enzyme assembly by directly binding to NCF2/P67PHOX. The extracellular functions involve pro-inflammatory, antimicrobial, oxidant-scavenging and apoptosis-inducing activities. Its pro-inflammatory activity includes recruitment of leukocytes, promotion of cytokine and chemokine production, and regulation of leukocyte adhesion and migration. Acts as an alarmin or a danger associated molecular pattern (DAMP) molecule and stimulates innate immune cells via binding to pattern recognition receptors such as Toll-like receptor 4 (TLR4) and receptor for advanced glycation endproducts (AGER). Binding to TLR4 and AGER activates the MAP-kinase and NF-kappa-B signaling pathways resulting in the amplification of the pro-inflammatory cascade. Has antimicrobial activity towards bacteria and fungi and exerts its antimicrobial activity probably via chelation of Zn(2+) which is essential for microbial growth. Can induce cell death via autophagy and apoptosis and this occurs through the cross-talk of mitochondria and lysosomes via reactive oxygen species (ROS) and the process involves BNIP3. Can regulate neutrophil number and apoptosis by an anti-apoptotic effect; regulates cell survival via ITGAM/ITGB and TLR4 and a signaling mechanism involving MEK-ERK. Its role as an oxidant scavenger has a protective role in preventing exaggerated tissue damage by scavenging oxidants (By similarity). The iNOS-S100A8/A9 transnitrosylase complex is proposed to direct selective inflammatory stimulus-dependent S-nitrosylation of multiple targets such as GAPDH, ANXA5, EZR, MSN and VIM by recognizing a [IL]-x-C-x-x-[DE] motif; S100A8 seems to contribute to S-nitrosylation site selectivity (By similarity).", "evidence": [ { "database": "UniProtKB", "id": "P28782", "url": "https://www.uniprot.org/uniprotkb/P28782#function" }, { "database": "UniProtKB", "id": "P05109", "url": "https://www.uniprot.org/uniprotkb/P05109#function" } ] }, { "annotation": "Study of nonsynonymous DNA variation in the functional domain of the S100A7, -A8, -A9 genes in taurine cattle and yak", "evidence": [ { "database": "RefSeq", "id": "NP_001107197", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001107197" }, { "database": "PubMed", "id": "29774569", "url": "https://glygen.org/publication/PubMed/29774569" } ] }, { "annotation": "The findings indicated that plasma concentrations of S100A7 and S100A8 did not change significantly during pregnancy in cows.", "evidence": [ { "database": "RefSeq", "id": "NP_001107197", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001107197" }, { "database": "PubMed", "id": "29604144", "url": "https://glygen.org/publication/PubMed/29604144" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Bos taurus", "taxid": 9913, "evidence": [ { "database": "UniProtKB", "id": "P28782", "url": "https://www.uniprot.org/uniprotkb/P28782" } ], "common_name": "Bovine", "glygen_name": "Bovine", "reference_species": "Bos taurus [9913]" } ], "gene": [ { "name": "S100A8", "url": "https://www.uniprot.org/uniprotkb/P28782", "locus": {} } ], "crossref": [ { "id": "P28782", "url": "https://alphafold.ebi.ac.uk/entry/P28782", "database": "AlphaFoldDB", "categories": [] }, { "id": "ENSBTAG00000012640", "url": "https://bgee.org/?page=gene&gene_id=ENSBTAG00000012640", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "cd05030", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd05030", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "616818", "url": "https://www.ncbi.nlm.nih.gov/gene/616818", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR001751", "url": "https://www.ebi.ac.uk/interpro/entry/IPR001751", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR002048", "url": "https://www.ebi.ac.uk/interpro/entry/IPR002048", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR011992", "url": "https://www.ebi.ac.uk/interpro/entry/IPR011992", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR013787", "url": "https://www.ebi.ac.uk/interpro/entry/IPR013787", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "bta:616818", "url": "https://www.genome.jp/dbget-bin/www_bget?bta:616818", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "NYHAIYR", "url": "https://omabrowser.org/oma/group/NYHAIYR/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "P28782", "url": "https://www.orthodb.org/?gene=P28782", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR11639", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR11639", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR11639:SF5", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR11639:SF5", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00036", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00036", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF01023", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF01023", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "R-BTA-5668599", "url": "https://www.reactome.org/PathwayBrowser/#R-BTA-5668599", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "R-BTA-5686938", "url": "https://www.reactome.org/PathwayBrowser/#R-BTA-5686938", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "R-BTA-6798695", "url": "https://www.reactome.org/PathwayBrowser/#R-BTA-6798695", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "R-BTA-6799990", "url": "https://www.reactome.org/PathwayBrowser/#R-BTA-6799990", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "NP_001107197", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001107197", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0AAF6YXT2", "url": "https://www.uniprot.org/uniprotkb/A0AAF6YXT2", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0AAF6YXT2-1", "url": "https://www.uniprot.org/uniprotkb/A0AAF6YXT2-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "P28782", "url": "https://www.uniprot.org/uniprotkb/P28782", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "P28782-1", "url": "https://www.uniprot.org/uniprotkb/P28782-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MLTDLECAINSLIDVYHKYSLKKGNYHAVYRDDLKQLLETECPKFMKKKDADTWFKELDINQDGGINFEEFLVLVIKVGLEAHEEIHKE", "length": 89, "header": "sp|P28782-1|S10A8_BOVIN Isoform 1 of Protein S100-A8 OS=Bos taurus OX=9913 GN=S100A8 PE=1 SV=2 CANONICAL=P28782-1" }, "isoforms": [ { "isoform_ac": "A0AAF6YXT2-1", "url": "https://www.uniprot.org/uniprotkb/A0AAF6YXT2/entry", "sequence": { "sequence": "MLTDLECAINSLIDVYHKYSLKKGNYHAVYRDDLKQLLETECPKFMKKKDADTWFKELDINQDGGINFEEFLVLVIKETWI", "length": 81, "header": "tr|A0AAF6YXT2-1|A0AAF6YXT2_BOVIN Computationally mapped isoform of EF-hand domain-containing protein OS=Bos taurus OX=9913 GN= PE=1 SV=1 CANONICAL=P28782-1" }, "locus": { "chromosome": "3", "start_pos": 17086739, "end_pos": 17086323, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000016774.5", "url": "https://www.ensembl.org/id/ENSBTAT00000016774.5" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000016774.4", "url": "https://www.ensembl.org/id/ENSBTAP00000016774.4" } ] } }, { "isoform_ac": "P28782-1", "url": "https://www.uniprot.org/uniprotkb/P28782/entry#P28782-1", "sequence": { "sequence": "MLTDLECAINSLIDVYHKYSLKKGNYHAVYRDDLKQLLETECPKFMKKKDADTWFKELDINQDGGINFEEFLVLVIKVGLEAHEEIHKE", "length": 89, "header": "sp|P28782-1|S10A8_BOVIN Isoform 1 of Protein S100-A8 OS=Bos taurus OX=9913 GN=S100A8 PE=1 SV=2 CANONICAL=P28782-1" }, "locus": {} } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [ { "title": "The 23-kilodalton protein, a substrate of protein kinase C, in bovine neutrophil cytosol is a member of the S100 family.", "journal": "Biochemistry", "date": "1992", "authors": "Dianoux A C, Stasia M J, Garin J, Gagnon J, Vignais P V", "evidence": [ { "database": "UniProtKB", "id": "P28782", "url": "https://www.uniprot.org/uniprotkb/P28782" } ], "reference": [ { "type": "PubMed", "id": "1610833", "url": "https://glygen.org/publication/PubMed/1610833" } ] }, { "title": "Influence of energy balance on the antimicrobial peptides S100A8 and S100A9 in the endometrium of the post-partum dairy cow.", "journal": "Reproduction (Cambridge, England)", "date": "2013-05", "authors": "Swangchan-Uthai Theerawat, Chen Qiusheng, Kirton Sally E, Fenwick Mark A, Cheng Zhangrui, Patton Joe, Fouladi-Nashta Ali A, Wathes D Claire", "evidence": [ { "database": "RefSeq", "id": "NP_001107197", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001107197" } ], "reference": [ { "type": "PubMed", "id": "23533291", "url": "https://glygen.org/publication/PubMed/23533291" } ] }, { "title": "Changes in plasma concentrations of S100A7 and S100A8 in dairy cows during pregnancy.", "journal": "Reproduction in domestic animals = Zuchthygiene", "date": "2018-08", "authors": "Elgawish R A, Ogata Y, Hidaka T, Nii T, Yoshimura Y, Isobe N", "evidence": [ { "database": "RefSeq", "id": "NP_001107197", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001107197" } ], "reference": [ { "type": "PubMed", "id": "29604144", "url": "https://glygen.org/publication/PubMed/29604144" } ] }, { "title": "Nonsynonymous DNA variation in the functional domain of the S100A7, -A8, -A9 genes in taurine cattle and yak.", "journal": "Animal genetics", "date": "2018-08", "authors": "Luo Zonggang, Wu Yuhui, Zhang Wen-Xiu, Wang Ling, Zuo Fuyuan, Zhang Gong-Wei", "evidence": [ { "database": "RefSeq", "id": "NP_001107197", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001107197" } ], "reference": [ { "type": "PubMed", "id": "29774569", "url": "https://glygen.org/publication/PubMed/29774569" } ] }, { "title": "Nuclear proteins of the bovine esophageal epithelium. I. Monoclonal antibody W2 specifically reacts with condensed nuclei of differentiated superficial cells.", "journal": "J. Cell Sci.", "date": "1993", "authors": "Tang T K, Hong T M, Lin C Y, Lai M L, Liu C H, Lo H J, Wang M E, Chen L B, Chen W T, Ip W", "evidence": [ { "database": "UniProtKB", "id": "P28782", "url": "https://www.uniprot.org/uniprotkb/P28782" } ], "reference": [ { "type": "PubMed", "id": "8505358", "url": "https://glygen.org/publication/PubMed/8505358" } ] } ], "pathway": [ { "id": "bta:616818", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?bta:616818", "resource": "KEGG Pathway" }, { "id": "R-BTA-5668599", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-BTA-5668599", "resource": "Reactome", "description": "RHO GTPases Activate NADPH Oxidases" }, { "id": "R-BTA-5686938", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-BTA-5686938", "resource": "Reactome", "description": "Regulation of TLR by endogenous ligand" }, { "id": "R-BTA-6798695", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-BTA-6798695", "resource": "Reactome", 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"IPR027417", "url": "https://www.ebi.ac.uk/interpro/entry/IPR027417", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "bta:281789", "url": "https://www.genome.jp/dbget-bin/www_bget?bta:281789", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "LRIHYVC", "url": "https://omabrowser.org/oma/group/LRIHYVC/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "A0A3Q1MUH6", "url": "https://www.orthodb.org/?gene=A0A3Q1MUH6", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "P38408", "url": "https://www.orthodb.org/?gene=P38408", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR10218", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR10218", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR10218:SF213", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR10218:SF213", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00503", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00503", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "R-BTA-112043", "url": "https://www.reactome.org/PathwayBrowser/#R-BTA-112043", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "R-BTA-202040", "url": "https://www.reactome.org/PathwayBrowser/#R-BTA-202040", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "R-BTA-399997", "url": "https://www.reactome.org/PathwayBrowser/#R-BTA-399997", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "R-BTA-416476", "url": "https://www.reactome.org/PathwayBrowser/#R-BTA-416476", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "R-BTA-418592", "url": "https://www.reactome.org/PathwayBrowser/#R-BTA-418592", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "R-BTA-428930", "url": "https://www.reactome.org/PathwayBrowser/#R-BTA-428930", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "R-BTA-434316", "url": "https://www.reactome.org/PathwayBrowser/#R-BTA-434316", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "R-BTA-456926", "url": "https://www.reactome.org/PathwayBrowser/#R-BTA-456926", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "R-BTA-6814122", "url": "https://www.reactome.org/PathwayBrowser/#R-BTA-6814122", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "NP_776748", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_776748", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A3Q1MUH6", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1MUH6", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A3Q1MUH6-1", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1MUH6-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0AAF6Z8T9", "url": "https://www.uniprot.org/uniprotkb/A0AAF6Z8T9", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0AAF6Z8T9-1", "url": "https://www.uniprot.org/uniprotkb/A0AAF6Z8T9-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "P38408", "url": "https://www.uniprot.org/uniprotkb/P38408", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "P38408-1", "url": "https://www.uniprot.org/uniprotkb/P38408-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MAGCCCLSAEEKESQRISAEIERQLRRDKKDARRELKLLLLGTGESGKSTFIKQMRIIHGSGYSDEDRKGFTKLVYQNIFTAMQAMIRAMDTLKIQYVCEQNKENAQLIREVEVDKVSTLSRDQVEAIKQLWQDPGIQECYDRRREYQLSDSAKYYLTDIDRIAMPAFVPTQQDVLRVRVPTTGIIEYPFDLENIIFRMVDVGGQRSERRKWIHCFESVTSIIFLVALSEYDQVLAECDNENRMEESKALFKTIITYPWFLNSSVILFLNKKDLLEEKIMYSHLISYFPEYTGPKQDVKAARDFILKLYQDQNPDKEKVIYSHFTCATDTENIRFVFAAVKDTILQLNLREFNLV", "length": 355, "header": "sp|P38408-1|GNA14_BOVIN Isoform 1 of Guanine nucleotide-binding protein subunit alpha-14 OS=Bos taurus OX=9913 GN=GNA14 PE=2 SV=1 CANONICAL=P38408-1" }, "isoforms": [ { "isoform_ac": "A0A3Q1MUH6-1", "url": "https://www.uniprot.org/uniprotkb/A0A3Q1MUH6/entry", "sequence": { "sequence": "MAGCCCLSAEEKESQRISAEIERQLRRDKKDARRELKLLLLGTGESGKSTFIKQMRIIHGSGYSDEDRKGFTKLVYQNIFTAMQAMIRAMDTLKIQYVCEQNKENAQLIREVEVDKVSTLSRDQVEAIKQLWQDPGIQECYDRRREYQLSDSAKYYLTDIDRIAMPAFVPTQQDVLRVRVPTTGIIEYPFDLENIIFRMVDVGGQRSERRKWIHCFESVTSIIFLVALSEYDQVLAECDNENRMEESKALFKTIITYPWFLNSSVILFLNKKDLLEEKIMYSHLISYFPEYTAHKYANMTSEKSESFCTCTGERTVTFLLPSTASI", "length": 326, "header": "tr|A0A3Q1MUH6-1|A0A3Q1MUH6_BOVIN Computationally mapped isoform of Guanine nucleotide-binding protein subunit alpha OS=Bos taurus OX=9913 GN=GNA14 PE=3 SV=2 CANONICAL=P38408-1" }, "locus": { "chromosome": "8", "start_pos": 53663302, "end_pos": 53363556, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000068584.2", "url": "https://www.ensembl.org/id/ENSBTAT00000068584.2" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000058528.2", "url": "https://www.ensembl.org/id/ENSBTAP00000058528.2" } ] } }, { "isoform_ac": "A0AAF6Z8T9-1", "url": "https://www.uniprot.org/uniprotkb/A0AAF6Z8T9/entry", "sequence": { "sequence": "MAGCCCLSAEEKESQRISAEIERQLRRDKKDARRELKLLLLGTGESGKSTFIKQMRIIHGSGYSDEDRKGFTKLVYQNIFTAMQAMIRAMDTLKIQYVCEQNKENAQLIREVEVDKVSTLSRDQVEAIKQLWQDPGIQECYDRRREYQLSDSAKYILLSNTSYLTDIDRIAMPAFVPTQQDVLRVRVPTTGIIEYPFDLENIIFRMVDVGGQRSERRKWIHCFESVTSIIFLVALSEYDQVLAECDNENRMEESKALFKTIITYPWFLNSSVILFLNKKDLLEEKIMYSHLISYFPEYTGPKQDVKAARDFILKLYQDQNPDKEKVIYSHFTCATDTENIRFVFAAVKDTILQLNLREFNLV", "length": 362, "header": "tr|A0AAF6Z8T9-1|A0AAF6Z8T9_BOVIN Computationally mapped isoform of Guanine nucleotide-binding protein subunit alpha OS=Bos taurus OX=9913 GN=GNA14 PE=3 SV=1 CANONICAL=P38408-1" }, "locus": { "chromosome": "8", "start_pos": 53663302, "end_pos": 53465646, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000028151.4", "url": "https://www.ensembl.org/id/ENSBTAT00000028151.4" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000028151.3", "url": "https://www.ensembl.org/id/ENSBTAP00000028151.3" } ] } }, { "isoform_ac": "P38408-1", "url": "https://www.uniprot.org/uniprotkb/P38408/entry#P38408-1", "sequence": { "sequence": "MAGCCCLSAEEKESQRISAEIERQLRRDKKDARRELKLLLLGTGESGKSTFIKQMRIIHGSGYSDEDRKGFTKLVYQNIFTAMQAMIRAMDTLKIQYVCEQNKENAQLIREVEVDKVSTLSRDQVEAIKQLWQDPGIQECYDRRREYQLSDSAKYYLTDIDRIAMPAFVPTQQDVLRVRVPTTGIIEYPFDLENIIFRMVDVGGQRSERRKWIHCFESVTSIIFLVALSEYDQVLAECDNENRMEESKALFKTIITYPWFLNSSVILFLNKKDLLEEKIMYSHLISYFPEYTGPKQDVKAARDFILKLYQDQNPDKEKVIYSHFTCATDTENIRFVFAAVKDTILQLNLREFNLV", "length": 355, "header": "sp|P38408-1|GNA14_BOVIN Isoform 1 of Guanine nucleotide-binding protein subunit alpha-14 OS=Bos taurus OX=9913 GN=GNA14 PE=2 SV=1 CANONICAL=P38408-1" }, "locus": {} } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [ { "title": "Identification of two novel GTP-binding protein alpha-subunits that lack apparent ADP-ribosylation sites for pertussis toxin.", "journal": "J. Biol. Chem.", "date": "1991", "authors": "Nakamura F, Ogata K, Shiozaki K, Kameyama K, Ohara K, Haga T, Nukada T", "evidence": [ { "database": "UniProtKB", "id": "P38408", "url": "https://www.uniprot.org/uniprotkb/P38408" } ], "reference": [ { "type": "PubMed", "id": "1905731", "url": "https://glygen.org/publication/PubMed/1905731" } ] } ], "pathway": [ { "id": "bta:281789", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?bta:281789", "resource": "KEGG Pathway" }, { "id": "R-BTA-112043", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-BTA-112043", "resource": "Reactome", "description": "PLC beta mediated events" }, { "id": "R-BTA-202040", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-BTA-202040", "resource": "Reactome", "description": "G-protein activation" }, { "id": "R-BTA-399997", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-BTA-399997", "resource": "Reactome", "description": "Acetylcholine regulates insulin secretion" }, { "id": "R-BTA-416476", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-BTA-416476", "resource": "Reactome", "description": "G alpha (q) signalling events" }, { "id": "R-BTA-418592", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-BTA-418592", "resource": "Reactome", "description": "ADP signalling through P2Y purinoceptor 1" }, { "id": "R-BTA-428930", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-BTA-428930", "resource": "Reactome", "description": "Thromboxane signalling through TP receptor" }, { "id": "R-BTA-434316", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-BTA-434316", "resource": "Reactome", "description": "Fatty Acids bound to GPR40 (FFAR1) regulate insulin secretion" }, { "id": "R-BTA-456926", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-BTA-456926", "resource": "Reactome", "description": "Thrombin signalling through proteinase activated receptors (PARs)" }, { "id": "R-BTA-6814122", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-BTA-6814122", "resource": "Reactome", "description": "Cooperation of PDCL (PhLP1) and TRiC/CCT in G-protein beta folding" } ], "orthologs": [ { "uniprot_canonical_ac": "A0A8J8XRQ3-1", "protein_name": "Guanine nucleotide-binding protein subunit alpha", "gene_name": "Gna14", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MAGCCCLSAEEKESQRISAEIERQLRRDKKDARRELKLLLLGTGESGKSTFIKQMRIIHGSGYSDEDRKGFTKLVYQNIFTAMQAMIRAMDTLRIQYTCEQNKENAQIIREVEVDKVSAISRDQVAAIKQLWLDPGIQECYDRRREYQLSDSAKYYLTDIDRIAMPSFVPTQQDVLRVRVPTTGIIEYPFDLENIIFRRMVDVGGQRSERRKWIHCFESVTSIIFLVALSEYDQVLAECDNENRMEESKALFKTIITYPWFLNSSVILFLNKKDLLEEKIMYSHLISYFPEYTGPKQDVKAARDFILKLYQDQNPDKEKVIYSHFTCATDTENIRFVFAAVKDTILQLNLREFNLV", "length": 356 }, "evidence": [ { "id": "P38408", "url": "https://omabrowser.org/oma/group/P38408/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "A0A8V0YKB4-1", "protein_name": "Guanine nucleotide-binding protein subunit alpha", "gene_name": "GNA14", "tax_id": 9031, "organism": "Gallus gallus", "sequence": { "sequence": "MAGRCLSADEKESQRISAEIERQLRRDKRDARRELKLLLLGTGESGKSTFIKQMRIIHGSGYTEEDRKGFTKLVYRNIFTAMQAMIRAMDILKIQYASEENEENAQMIRRVEVDKVTALERKQVEAIKNLWDDPGIQECYDRRREYQLSDSAKYYLTNIDRIAMPSFVPTQQDILRVRVPTTGIIEYPFDLENVIFRMVDVGGQRSERRKWIHCFESVTYIFLVALSEYDQVLAECDNENRMKESKALFKTIITYPWFLNSSVILFLNKKDLLEEKIMYSHLTSYFPEYTGPKQDVKAAGDFILKLYQDQNPDKQKVIYSHFTCATDTENIRFVFAAVKDTILQLNLREFNLV", "length": 353 }, "evidence": [ { "id": "P38408", "url": "https://omabrowser.org/oma/group/P38408/", "database": "OMA" } ], "glygen_name": "Chicken", "common_name": "Chicken" }, { "uniprot_canonical_ac": "O95837-1", "protein_name": "Guanine nucleotide-binding protein subunit alpha-14", "gene_name": "GNA14", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MAGCCCLSAEEKESQRISAEIERQLRRDKKDARRELKLLLLGTGESGKSTFIKQMRIIHGSGYSDEDRKGFTKLVYQNIFTAMQAMIRAMDTLRIQYVCEQNKENAQIIREVEVDKVSMLSREQVEAIKQLWQDPGIQECYDRRREYQLSDSAKYYLTDIDRIATPSFVPTQQDVLRVRVPTTGIIEYPFDLENIIFRMVDVGGQRSERRKWIHCFESVTSIIFLVALSEYDQVLAECDNENRMEESKALFKTIITYPWFLNSSVILFLNKKDLLEEKIMYSHLISYFPEYTGPKQDVRAARDFILKLYQDQNPDKEKVIYSHFTCATDTDNIRFVFAAVKDTILQLNLREFNLV", "length": 355 }, "evidence": [ { "id": "P38408", "url": "https://omabrowser.org/oma/group/P38408/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "P30677-1", "protein_name": "Guanine nucleotide-binding protein subunit alpha-14", "gene_name": "Gna14", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": 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"uniprotkb_ligand_comment": "", "eco_id": "ECO_0000250", "start_pos": 182, "end_pos": 182, "start_aa": "Thr", "end_aa": "Thr", "glycosite_overlap": [] }, { "evidence": [ { "id": "PIRSR601019-2", "database": "PIR Site Rule", "url": "https://proteininformationresource.org/cgi-bin/pirrule?id=PIRSR601019-2" } ], "binding_site_uniprot": 189, "amino_acid": "Pro", "chebi_lig_id": "CHEBI:18420", "ligand": "Mg(2+)", "ligand_label": "", "uniprotkb_ligand_comment": "", "eco_id": "ECO_0000256", "start_pos": 189, "end_pos": 189, "start_aa": "Pro", "end_aa": "Pro", "glycosite_overlap": [] }, { "evidence": [ { "id": "P38408", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P38408" }, { "id": "PIRSR601019-2", "database": "PIR Site Rule", "url": "https://proteininformationresource.org/cgi-bin/pirrule?id=PIRSR601019-2" } ], "binding_site_uniprot": 49, "amino_acid": "Ser", "chebi_lig_id": "CHEBI:18420", "ligand": "Mg(2+)", "ligand_label": "", "uniprotkb_ligand_comment": "", "eco_id": 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"count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ], "tool_support": { "graph_view": "yes" } }, { "uniprot_canonical_ac": "Q32KW7-1", "uniprot_ac": "Q32KW7", "uniprot_id": "PDZD9_BOVIN", "mass": { "chemical_mass": 29794.0, "monoisotopic_mass": 29794.0 }, "refseq": { "ac": "NP_001069562", "name": "PDZ domain-containing protein 9", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001069562" }, "gene_names": [ { "name": "PDZD9", "type": "recommended", "evidence": [ { "id": "Q32KW7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q32KW7" } ] }, { "name": "C16orf65", "type": "synonym", "evidence": [ { "id": "NP_001069562", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001069562" } ] }, { "name": "C25H16orf65", "type": "synonym", "evidence": [ { "id": "NP_001069562", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001069562" } ] }, { "name": "PDZD9", "type": "synonym", "evidence": [ { "id": "NP_001069562", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001069562" } ] } ], "protein_names": [ { "name": "PDZ domain-containing protein 9", "type": "recommended", "evidence": [ { "id": "Q32KW7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q32KW7/entry#names_and_taxonomy" } ] }, { "name": "PDZ domain-containing protein 9", "type": "synonym", "evidence": [ { "id": "NP_001069562", "database": "RefSeq", "url": 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"A0AAA9T5I2", "url": "https://www.uniprot.org/uniprotkb/A0AAA9T5I2", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0AAA9T5I2-1", "url": "https://www.uniprot.org/uniprotkb/A0AAA9T5I2-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "Q32KW7", "url": "https://www.uniprot.org/uniprotkb/Q32KW7", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "Q32KW7-1", "url": "https://www.uniprot.org/uniprotkb/Q32KW7-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MKKSVQKNVKGKQVNLKVKPSVHDLSKTQQTKLTVGSMGLGLIIIQHGPYLQISHLITKGAAARDGTLQPGDVLISVGYANVLGYTLREFLKLLQHITIGTILQIKVYRDFIDIPQEWQEIYDLIPETKFPITRTTKKTEEAKDGSVTSSDDDEAFDTRLKYYKYPRSTGHYPVRRPMSISREWHGYKKKNHVMRVGKDINCDVMIHRDHKKEVRAPSPYWTMVKQDNEISSSSSASSTSDAFWLEDCTPVEKGSSEPVSRVG", "length": 263, "header": "sp|Q32KW7-1|PDZD9_BOVIN Isoform 1 of PDZ domain-containing protein 9 OS=Bos taurus OX=9913 GN=PDZD9 PE=2 SV=1 CANONICAL=Q32KW7-1" }, "isoforms": [ { "isoform_ac": 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"https://www.uniprot.org/uniprotkb/A0AAA9T5I2/entry", "sequence": { "sequence": "MKKSVQKNVKGDVLISVGYANVLGYTLREFLKLLQHITIGTILQIKVYRDFIDIPQEWQEIYDLIPETKFPITRTTKKTEEAKDGSVTSSDDDEAFDTRLKYYKYPRSTGHYPVRRPMSISREWHGYKKKNHVMRVGKDINCDVMIHRDHKKEVRAPSPYWTMVKQDNEISSSSSASSTSDAFWLEDCTPVEKGSSEPVSRVG", "length": 203, "header": "tr|A0AAA9T5I2-1|PDZD9_BOVIN Computationally mapped isoform of PDZ domain-containing protein 9 OS=Bos taurus OX=9913 GN=PDZD9 PE=2 SV=1 CANONICAL=Q32KW7-1" }, "locus": { "chromosome": "25", "start_pos": 19687977, "end_pos": 19674102, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000113717.1", "url": "https://www.ensembl.org/id/ENSBTAT00000113717.1" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000093082.1", "url": "https://www.ensembl.org/id/ENSBTAP00000093082.1" } ] } }, { "isoform_ac": "Q32KW7-1", "url": "https://www.uniprot.org/uniprotkb/Q32KW7/entry#Q32KW7-1", "sequence": { "sequence": "MKKSVQKNVKGKQVNLKVKPSVHDLSKTQQTKLTVGSMGLGLIIIQHGPYLQISHLITKGAAARDGTLQPGDVLISVGYANVLGYTLREFLKLLQHITIGTILQIKVYRDFIDIPQEWQEIYDLIPETKFPITRTTKKTEEAKDGSVTSSDDDEAFDTRLKYYKYPRSTGHYPVRRPMSISREWHGYKKKNHVMRVGKDINCDVMIHRDHKKEVRAPSPYWTMVKQDNEISSSSSASSTSDAFWLEDCTPVEKGSSEPVSRVG", "length": 263, "header": "sp|Q32KW7-1|PDZD9_BOVIN Isoform 1 of PDZ domain-containing protein 9 OS=Bos taurus OX=9913 GN=PDZD9 PE=2 SV=1 CANONICAL=Q32KW7-1" }, "locus": { "chromosome": "25", "start_pos": 19687977, "end_pos": 19674102, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000028854.4", "url": "https://www.ensembl.org/id/ENSBTAT00000028854.4" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000028854.3", "url": "https://www.ensembl.org/id/ENSBTAP00000028854.3" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [ { "id": "bta:537386", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?bta:537386", "resource": "KEGG Pathway" } ], "orthologs": [ { "uniprot_canonical_ac": "A0A0G2K409-1", "protein_name": "PDZ domain containing 9", "gene_name": "Pdzd9", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MEKDSSKSKNEKEYNHRASLNKMIHTKLTVGSLGLGLVIIQNGPYLQISHLINKGAAASDGILQPAVFEQCVYGRHMALEGESMTARDAGQQCVGMEVTGGSWLLHAQTVQYRNEDTTDTEGTTDTEKLGLVAVLTLLEGDVLISVGHANVLGYTLREFLKLLQNITIGTVLQIKAYRGFIEIPQEWKDVYDLIPETKFPIPHTPKKTEQAKQSFESDEHEDTVLDHRLKYYRYPRSVWNHPVRIPLSISTEWHGYKKKDNTISVGKDVKSDVVIHKDDEKELRAPSPYWAMVEQDERISSSSSPASSISDAFWLEDFAQDKEGKGEQVSKFG", "length": 333 }, "evidence": [ { "id": "Q32KW7", "url": "https://omabrowser.org/oma/group/Q32KW7/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "Q8IXQ8-1", "protein_name": "PDZ domain-containing protein 9", "gene_name": "PDZD9", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MQKASHKNKKERGVSNKVKTSVHNLSKTQQTKLTVGSLGLGLIIIQHGPYLQITHLIRKGAAANDGKLQPGDVLISVGHANVLGYTLREFLQLLQHITIGTVLQIKVYRDFINIPEEWQEIYDLIPEAKFPVTSTPKKIELAKDESFTSSDDNENVDLDKRLQYYRYPWSTVHHPARRPISISRDWHGYKKKNHTISVGKDINCDVMIHRDDKKEVRAPSPYWIMVKQDNESSSSSTSSTSDAFWLEDCAQVEEGKAQLVSKVG", "length": 264 }, "evidence": [ { "id": "Q32KW7", "url": "https://omabrowser.org/oma/group/Q32KW7/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "Q9D9M4-1", "protein_name": "PDZ domain-containing protein 9", "gene_name": "Pdzd9", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MEKGSLKSKNEKEQLSKAKASVSSLNKVIQTKLTVGNLGLGLVVIQNGPYLQISHLINKGAAASDGILQPGDVLISVGHANVLGYTLREFLKLLQNITIGTVLQIKAYRGFLEIPQEWQDVYDLIPETKFPIPHTPKKTEPARESLVKDDHEEAVLDKKLKYYRYPRSVWNHPVRTPISISTEWHGYEKKERTISVGRDINSDVVIHKDDKKELRAPSPYWAMVEQDRAISSSSSSTANSSSSDAFWLEDYAQVEEGNGKQVSKFG", "length": 266 }, "evidence": [ { "id": "Q32KW7", "url": "https://omabrowser.org/oma/group/Q32KW7/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" } ], "go_annotation": {}, "pro_annotation": [], "site_annotation": [], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [ { "pdb_id": "AF-Q32KW7-F1", "pdb_chain": "global", "start_pos": 1, "end_pos": 263, "overlap": "1.0", "method": "AlphaFold", "type": "alphafold", "resolution": -1.0, "url": "https://data.glygen.org/ln2downloads/pdb/current/AF-Q32KW7-F1.pdb", "url_external": "https://alphafold.ebi.ac.uk/entry/Q32KW7" } ], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "Q32KW7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q32KW7" }, { "id": "PRU00143", "database": "PROSITE", "url": "https://prosite.expasy.org/PRU00143" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "PDZ", "eco_id": "ECO_0000255", "start_pos": 30, "end_pos": 109, "start_aa": "Gln", "end_aa": "Arg", "glycosite_overlap": [] } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" }, { "name": "homologset.oma", "label": "OMA Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": 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0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ], "tool_support": { "graph_view": "yes" } }, { "uniprot_canonical_ac": "Q3T028-1", "uniprot_ac": "Q3T028", "uniprot_id": "TSG13_BOVIN", "mass": { "chemical_mass": 31827.0, "monoisotopic_mass": 31827.0 }, "refseq": { "ac": "NP_001069894", "name": "testis-specific gene 13 protein", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001069894" }, "gene_names": [ { "name": "TSGA13", "type": "recommended", "evidence": [ { "id": "Q3T028", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q3T028" } ] }, { 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"https://www.uniprot.org/uniprotkb/Q3T028", "locus": { "chromosome": "4", "start_pos": 94443863, "end_pos": 94468216, "strand": "+", "evidence": [ { "database": "Ensembl Gene", "id": "ENSBTAG00000020183", "url": "https://www.ensembl.org/id/ENSBTAG00000020183" } ] } } ], "crossref": [ { "id": "Q3T028", "url": "https://alphafold.ebi.ac.uk/entry/Q3T028", "database": "AlphaFoldDB", "categories": [] }, { "id": "ENSBTAG00000020183", "url": "https://bgee.org/?page=gene&gene_id=ENSBTAG00000020183", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "616493", "url": "https://www.ncbi.nlm.nih.gov/gene/616493", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR029241", "url": "https://www.ebi.ac.uk/interpro/entry/IPR029241", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "bta:616493", "url": "https://www.genome.jp/dbget-bin/www_bget?bta:616493", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "WIIKNAT", "url": "https://omabrowser.org/oma/group/WIIKNAT/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "Q3T028", "url": "https://www.orthodb.org/?gene=Q3T028", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR37352", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR37352", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR37352:SF1", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR37352:SF1", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF14994", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF14994", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "NP_001069894", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001069894", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0AAA9T5T2", "url": "https://www.uniprot.org/uniprotkb/A0AAA9T5T2", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0AAA9T5T2-1", "url": "https://www.uniprot.org/uniprotkb/A0AAA9T5T2-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "Q3T028", "url": "https://www.uniprot.org/uniprotkb/Q3T028", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "Q3T028-1", "url": "https://www.uniprot.org/uniprotkb/Q3T028-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MGQRRQTKSQHAKPRTFRTSPVMFEKEIFFDSDEIIDAVGQSKFVLKNLHHYTVHPNLAQYYEPLKPTALQKFLARNRKIQSFTLKVIEYDQDKTLLILTNNPLPCPIDHQGKDVTPKYFSNELLLKESHQHKPTENFFLPLMPQKKNLRSGLKPVFPLMLLEDTKSKREQWFRFSTDNDFKSEGKYSKVYTLRQQKKMYPQLTFASVCKKYMKNDVSKKSGSDSPTSQMIWEPLTLSSLLEKKPTRTAPGESEFRNGRAQQWFIKSATVIK", "length": 272, "header": "sp|Q3T028-1|TSG13_BOVIN Isoform 1 of Testis-specific gene 13 protein OS=Bos taurus OX=9913 GN=TSGA13 PE=2 SV=2 CANONICAL=Q3T028-1" }, "isoforms": [ { "isoform_ac": "A0AAA9T5T2-1", "url": "https://www.uniprot.org/uniprotkb/A0AAA9T5T2/entry", "sequence": { "sequence": "GGQERVEDHTSQHAKPRTFRTSPVMFEKEIFFDSDEIIDAVGQSKFVLKNLHHYTVHPNLAQYYEPLKPTALQKFLARNRKIQSFTLKVIEYDQDKTLLILTNNPLPCPIDHQGKDVTPKYFSNELLLKESHQHKPTENFFLPLMPQKKNLRSGLKPVFPLMLLEDTKSKREQWFRFSTDNDFKSEGKYSKVYTLRQQKKMYPQLTFASVCKKYMKNDVSKKSGSDSPTSQMIWEPLTLSSLLEKKPTRTAPGESEFRNGRAQQWFIKSATVIK", "length": 274, "header": "tr|A0AAA9T5T2-1|TSG13_BOVIN Computationally mapped isoform of Testis-specific gene 13 protein OS=Bos taurus OX=9913 GN=TSGA13 PE=2 SV=1 CANONICAL=Q3T028-1" }, "locus": { "chromosome": "4", "start_pos": 94464305, "end_pos": 94443970, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000094234.1", "url": "https://www.ensembl.org/id/ENSBTAT00000094234.1" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000094124.1", "url": "https://www.ensembl.org/id/ENSBTAP00000094124.1" } ] } }, { "isoform_ac": "Q3T028-1", "url": "https://www.uniprot.org/uniprotkb/Q3T028/entry#Q3T028-1", "sequence": { "sequence": "MGQRRQTKSQHAKPRTFRTSPVMFEKEIFFDSDEIIDAVGQSKFVLKNLHHYTVHPNLAQYYEPLKPTALQKFLARNRKIQSFTLKVIEYDQDKTLLILTNNPLPCPIDHQGKDVTPKYFSNELLLKESHQHKPTENFFLPLMPQKKNLRSGLKPVFPLMLLEDTKSKREQWFRFSTDNDFKSEGKYSKVYTLRQQKKMYPQLTFASVCKKYMKNDVSKKSGSDSPTSQMIWEPLTLSSLLEKKPTRTAPGESEFRNGRAQQWFIKSATVIK", "length": 272, "header": "sp|Q3T028-1|TSG13_BOVIN Isoform 1 of Testis-specific gene 13 protein OS=Bos taurus OX=9913 GN=TSGA13 PE=2 SV=2 CANONICAL=Q3T028-1" }, "locus": { "chromosome": "4", "start_pos": 94466874, "end_pos": 94443970, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000026883.5", "url": "https://www.ensembl.org/id/ENSBTAT00000026883.5" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000026883.4", "url": "https://www.ensembl.org/id/ENSBTAP00000026883.4" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [ { "id": "bta:616493", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?bta:616493", "resource": "KEGG Pathway" } ], "orthologs": [ { "uniprot_canonical_ac": "A0A9J7KDX2-1", "protein_name": "Testis-specific gene 13 protein isoform X2", "gene_name": "Tsga13", "tax_id": 10029, "organism": "Cricetulus griseus", "sequence": { "sequence": "MLEDCRIPGPAIKMGWRKVVLALEVSASLPSALLMEFNLLLPGQDQPVLGDPWVTDQPVVFSTGLQGNEEMERESWKCLWTHGARHEFSHARLPPVHLTSRHFLLPQLLSLPALLHRGRPWIPVPLNCVQNVLTYVRPYIVTSREKNLHSKTTCDIQIILPSTTPLLRDASACPGTSTGTERVGKKLSQPPWSTEETMDGHLCREHTDISTALVCGCGQRALDQTVLTVRPKETPRALGTEHLLWEVEELEGRPAVCSLKLQGKVKEKTEEWWHVYHPCKHYLGNKRSPGNYGLLPTCTNPNMLDTTRYGLGRRWRGPGRG", "length": 321 }, "evidence": [ { "id": "Q3T028", "url": "https://omabrowser.org/oma/group/Q3T028/", "database": "OMA" } ], "glygen_name": "Hamster", "common_name": "Chinese hamster" }, { "uniprot_canonical_ac": "D3ZMN0-1", "protein_name": "Testis specific, 13", "gene_name": "Tsga13", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MGPKKNSKLQESGGSKTSIKFEKQLGPDDEEMYDTTAQSKFVLKNLRHYTVHPNMAQYYEPLKPSKLQRFLTQRKKTNSFMVKVTEYDQDMTLLLMTNNPPPYSIGQQENNGAPIYFPPEFQLKETVYRREPNKNDFLPTMSQKKKLKPVLKPIFPMKRIGDPNFKGQQWFRFSTDKDFKIEGRYSEVHALRKQKKMYPNLIFAPVDQRETRKQVSMKSADETPTSQVLWEPLTFSKLLEEKPTRSVPGESCFRYGRAQQWVVKNAAVIK", "length": 270 }, "evidence": [ { "id": "Q3T028", "url": "https://omabrowser.org/oma/group/Q3T028/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "Q96PP4-1", "protein_name": "Testis-specific gene 13 protein", "gene_name": "TSGA13", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MSQKRQTKFQNGKSKTSENSSAKREKGMVVNSKEISDAVGQSKFVLENLRHYTVHPNLAQYYKPLKATALQKFLAQNRKNTSFMLKVTQYDQDKTLLIMTNNPPPCSITQQDKESASKYFSKELLLKVMESHHQHKPTENLWLPRMPQKKKLRSKLKPIFPLILSDDPTSKREQWFRFSTDNDFKSEGKYSKVYALRTQKKMYPQLTFAPVHERDMRKDASKKSASERPISKVIREPLTLASLLEDMPTRTAPGESAFRNGRAPQWIIKKATVIG", "length": 275 }, "evidence": [ { "id": "Q3T028", "url": "https://omabrowser.org/oma/group/Q3T028/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "Q9DA17-1", "protein_name": "Testis-specific gene 13 protein", "gene_name": "Tsga13", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MGPKKNSKFQEVSGSKPVGNVSIRFEKQLGQDDEEMYDTTAQSKFVLKNLRHYTVHPNMAKYYEPLKPTKLQRFLTQKKKMNSFMLKVTEYDQDMTLLLMTNNPPPCSISQEKDGAPIYFPPEFQLKETLHRCKPNKNDFFPTMSQKKKLKPELKPVFPMKRLDDPTFKGQQWFRFSTDNDFNIEGKYSEIYALRKQKKMYPNLIFAPASQRETKKHVSMKSESETPTSQVFWEPLTFSKLLEEKPTRSVPGESFFRHGRAQQWIVKDAAVIW", "length": 273 }, "evidence": [ { "id": "Q3T028", "url": "https://omabrowser.org/oma/group/Q3T028/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" } ], "go_annotation": {}, "pro_annotation": [], "site_annotation": [], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [ { "pdb_id": "AF-Q3T028-F1", "pdb_chain": "global", "start_pos": 1, "end_pos": 272, "overlap": "1.0", "method": "AlphaFold", "type": "alphafold", "resolution": -1.0, "url": "https://data.glygen.org/ln2downloads/pdb/current/AF-Q3T028-F1.pdb", "url_external": "https://alphafold.ebi.ac.uk/entry/Q3T028" } ], "lectin_list": [], "domain_list": [], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" }, { "name": "homologset.oma", "label": "OMA Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": 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"Overexpressed in colon carcinoma 1 protein homolog", "type": "recommended", "evidence": [ { "id": "P0C914", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P0C914/entry#names_and_taxonomy" } ] }, { "name": "OCC-1", "type": "synonym", "evidence": [ { "id": "P0C914", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P0C914/entry#names_and_taxonomy" } ] }, { "name": "overexpressed in colon carcinoma 1 homolog", "type": "synonym", "evidence": [ { "id": "NP_001138674", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001138674" } ] }, { "name": "overexpressed in colon carcinoma 1 protein homolog", "type": "synonym", "evidence": [ { "id": "NP_001138674", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001138674" } ] } ], "function": [], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Bos taurus", "taxid": 9913, "evidence": [ { "database": 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"PTHR38502", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR38502", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR38502:SF1", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR38502:SF1", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF15506", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF15506", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "NP_001138674", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001138674", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0AAA9TF77", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TF77", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0AAA9TF77-1", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TF77-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0AAA9TJB4", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TJB4", "database": "UniProtKB", 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"isoform_ac": "A0AAA9TJB4-1", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TJB4/entry", "sequence": { "sequence": "SGWSPRAPRTRKSPAGLRLGARRPPPSSPPPGSAAASSRAWLPRPAARWAAGTPPPPARARAKNSYLLQLRSIRRHIPSQPANGPAGAAKDVTEESITEDDKRRNYGGVYVGLPSEAVNMVSNQTKTVQKN", "length": 131, "header": "tr|A0AAA9TJB4-1|OCC1_BOVIN Computationally mapped isoform of Overexpressed in colon carcinoma 1 protein homolog OS=Bos taurus OX=9913 GN=OCC1 PE=3 SV=1 CANONICAL=P0C914-1" }, "locus": {} }, { "isoform_ac": "A0AAA9TKE8-1", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TKE8/entry", "sequence": { "sequence": "MGCGNSTAASAGAGQETMEECMLVYHLKLSIWCPIRQRLCRKIRRRKYHDSIIKSLFIKIWMKFFPHGIL", "length": 70, "header": "tr|A0AAA9TKE8-1|OCC1_BOVIN Computationally mapped isoform of Overexpressed in colon carcinoma 1 protein homolog OS=Bos taurus OX=9913 GN=OCC1 PE=3 SV=1 CANONICAL=P0C914-1" }, "locus": { "chromosome": "5", "start_pos": 68867301, "end_pos": 68823508, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000123228.1", "url": "https://www.ensembl.org/id/ENSBTAT00000123228.1" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000098923.1", "url": "https://www.ensembl.org/id/ENSBTAP00000098923.1" } ] } }, { "isoform_ac": "A0AAA9TXH7-1", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TXH7/entry", "sequence": { "sequence": "MGCGNSTAASAGAGQGPAGAAKDVSFSGTDWVRFGYNFIDQLSSNSRI", "length": 48, "header": "tr|A0AAA9TXH7-1|A0AAA9TXH7_BOVIN Computationally mapped isoform of Chromosome 5 C12orf75 homolog OS=Bos taurus OX=9913 GN=C5H12orf75 PE=4 SV=1 CANONICAL=P0C914-1" }, "locus": { "chromosome": "5", "start_pos": 68887030, "end_pos": 68823508, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000098783.2", "url": "https://www.ensembl.org/id/ENSBTAT00000098783.2" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000101350.1", "url": "https://www.ensembl.org/id/ENSBTAP00000101350.1" } ] } }, { "isoform_ac": "P0C914-1", "url": "https://www.uniprot.org/uniprotkb/P0C914/entry#P0C914-1", "sequence": { "sequence": "MGCGNSTAASAGAGQGPAGAAKDVTEESITEDDKRRNYGGVYVGLPSEAVNMVSNQTKTVQKN", "length": 63, "header": "sp|P0C914-1|OCC1_BOVIN Isoform 1 of Overexpressed in colon carcinoma 1 protein homolog OS=Bos taurus OX=9913 GN=OCC1 PE=3 SV=1 CANONICAL=P0C914-1" }, "locus": { "chromosome": "5", "start_pos": 68861954, "end_pos": 68823508, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000130601.2", "url": "https://www.ensembl.org/id/ENSBTAT00000130601.2" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000097013.2", "url": "https://www.ensembl.org/id/ENSBTAP00000097013.2" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [ { "title": "Sequence evaluation of four pooled-tissue normalized bovine cDNA libraries and construction of a gene index for cattle.", "journal": "Genome Res.", "date": "2001", "authors": "Smith T P, Grosse W M, Freking 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Involved in the regulation of short-term and long-term synaptic plasticity.", "evidence": [ { "database": "UniProtKB", "id": "F1N548", "url": "https://www.uniprot.org/uniprotkb/F1N548#function" }, { "database": "UniProtKB", "id": "ARBA00046094", "url": "https://www.uniprot.org/uniprotkb/ARBA00046094#function" }, { "database": "UniProtKB", "id": "A0AAA9TH47", "url": "https://www.uniprot.org/uniprotkb/A0AAA9TH47#function" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Bos taurus", "taxid": 9913, "evidence": [ { "database": "UniProtKB", "id": "F1N548", "url": "https://www.uniprot.org/uniprotkb/F1N548" } ], "common_name": "Bovine", "glygen_name": "Bovine", "reference_species": "Bos taurus [9913]" } ], "gene": [ { "name": "SYP", "url": "https://www.uniprot.org/uniprotkb/F1N548", "locus": { "chromosome": "X", "start_pos": 87230211, "end_pos": 87242010, "strand": "+", "evidence": [ { "database": "Ensembl Gene", 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"MLLLADMDVVNQLVAGGQFRVVKEPLGFVKVLQWVFAIFAFATCGSYSGEFQLSVDCANKTKSDLNIEVEFEYPFRLHEVYFEAPTCQGDPKKIFLVGNYSSSAEFFVTVAVFAFLYSMGALATYIFLQNKYRENNKGPMLDFLATAVFAFMWLVSSSAWAKGLSDVKMATDPENIIKGMHVCHQPGNTCKELRDPVTSGLNTSVVFGFLNLVLWVGNLWFVFKETGWAAPFLRAPPGAPEKQPAPGDAYGEAGYGQGPGGYGPQDSYGPQGGYQPDYGQPASSGGGGYGPQGDYGQQGYGPQGAPTSFSNQM", "length": 313, "header": "tr|F1N548-1|F1N548_BOVIN Isoform 1 of Synaptophysin OS=Bos taurus OX=9913 GN=SYP PE=3 SV=1 CANONICAL=F1N548-1" }, "locus": { "chromosome": "X", "start_pos": 87241993, "end_pos": 87233978, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000021428.3", "url": "https://www.ensembl.org/id/ENSBTAT00000021428.3" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000021428.1", "url": "https://www.ensembl.org/id/ENSBTAP00000021428.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [ { "id": "bta:280937", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?bta:280937", "resource": "KEGG Pathway" } ], "orthologs": [ { "uniprot_canonical_ac": "B0S5B9-1", "protein_name": "Synaptophysin", "gene_name": "sypa", "tax_id": 7955, "organism": "Danio rerio", "sequence": { "sequence": "MDIANQLVAQGQFRVLKVPLGFIKILEWVFAIFAFSTCGSYSGSFRMSVECKNRSDSNLKIDVDFEYPFRLHQVYFNAPTCKNGQSDRFFLVGDYSSSAEFFVTIAVFAFLYSMAALSIYIFAFEKYRENNKGPLIDFGVTCVFTFMWLVSSAAWAKGLSDVKTATDPEKVLDLIPACENSGNRCREVYDPVMSGLNTSVVFGFLNLILWTGNLWFVFKETGIVAPFMRQQPAQEKQPAPDSYGQAGYGQQDPYAGSQGGYQPDYSQQGYNQGGDYGQGGYEQQGAPTSFSNQM", "length": 294 }, "evidence": [ { "id": "F1N548", "url": "https://omabrowser.org/oma/group/F1N548/", "database": "OMA" } ], "glygen_name": "Zebrafish", "common_name": "Zebrafish" }, { "uniprot_canonical_ac": "P07825-1", "protein_name": "Synaptophysin", "gene_name": "Syp", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MDVVNQLVAGGQFRVVKEPLGFVKVLQWVFAIFAFATCGSYTGELRLSVECANKTESALNIEVEFEYPFRLHQVYFDAPSCVKGGTTKIFLVGDYSSSAEFFVTVAVFAFLYSMGALATYIFLQNKYRENNKGPMMDFLATAVFAFMWLVSSSAWAKGLSDVKMATDPENIIKEMPMCRQTGNTCKELRDPVTSGLNTSVVFGFLNLVLWVGNLWFVFKETGWAAPFMRAPPGAPEKQPAPGDAYGDAGYGQGPGGYGPQDSYGPQGGYQPDYGQPASGGGGYGPQGDYGQQGYGQQGAPTSFSNQM", "length": 307 }, "evidence": [ { "id": "F1N548", "url": "https://omabrowser.org/oma/group/F1N548/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "P08247-1", "protein_name": "Synaptophysin", "gene_name": "SYP", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MLLLADMDVVNQLVAGGQFRVVKEPLGFVKVLQWVFAIFAFATCGSYSGELQLSVDCANKTESDLSIEVEFEYPFRLHQVYFDAPTCRGGTTKVFLVGDYSSSAEFFVTVAVFAFLYSMGALATYIFLQNKYRENNKGPMLDFLATAVFAFMWLVSSSAWAKGLSDVKMATDPENIIKEMPVCRQTGNTCKELRDPVTSGLNTSVVFGFLNLVLWVGNLWFVFKETGWAAPFLRAPPGAPEKQPAPGDAYGDAGYGQGPGGYGPQDSYGPQGGYQPDYGQPAGSGGSGYGPQGDYGQQGYGPQGAPTSFSNQM", "length": 313 }, "evidence": [ { "id": "F1N548", "url": "https://omabrowser.org/oma/group/F1N548/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "Q62277-1", "protein_name": "Synaptophysin", "gene_name": "Syp", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MLLLADMDVVNQLVAGGQFRVVKEPLGFVKVLQWVFAIFAFATCGSYTGELRLSVECANKTESALNIEVEFEYPFRLHQVYFDAPSCVKGGTTKIFLVGDYSSSAEFFVTVAVFAFLYSMGALATYIFLQNKYRENNKGPMMDFLATAVFAFMWLVSSSAWAKGLSDVKMATDPENIIKEMPMCRQTGNTCKELRDPVTSGLNTSVVFGFLNLVLWVGNLWFVFKETGWAAPFMRAPPGAPEKQPAPGDAYGDAGYGQGPGGYGPQDSYGPQGGYQPDYGQPASGGGGGYGPQGDYGQQGYGQQGAPTSFSNQM", "length": 314 }, "evidence": [ { "id": "F1N548", "url": "https://omabrowser.org/oma/group/F1N548/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" } ], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 11, "go_terms": [ { "name": "neuron projection", "id": "GO:0043005", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0043005", "evidence": [ { "database": "UniProtKB", "id": "F1N548", "url": "https://www.uniprot.org/uniprotkb/F1N548" } ], "pmid": "" }, { "name": "synaptic vesicle membrane", "id": "GO:0030672", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030672", "evidence": [ { "database": "UniProtKB", "id": "F1N548", "url": "https://www.uniprot.org/uniprotkb/F1N548" } ], "pmid": "" }, { "name": "neuromuscular junction", "id": "GO:0031594", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0031594", "evidence": [ { "database": "UniProtKB", "id": "F1N548", "url": "https://www.uniprot.org/uniprotkb/F1N548" } ], "pmid": "" }, { "name": "terminal bouton", "id": "GO:0043195", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0043195", "evidence": [ { "database": "UniProtKB", "id": "F1N548", "url": "https://www.uniprot.org/uniprotkb/F1N548" } ], "pmid": "" }, { "name": "perinuclear region of cytoplasm", "id": "GO:0048471", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0048471", "evidence": [ { "database": "UniProtKB", "id": "F1N548", "url": "https://www.uniprot.org/uniprotkb/F1N548" } ], "pmid": "" }, { "name": "presynaptic active zone", "id": "GO:0048786", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0048786", "evidence": [ { "database": "UniProtKB", "id": "F1N548", "url": "https://www.uniprot.org/uniprotkb/F1N548" } ], "pmid": "" }, { "name": "clathrin-coated vesicle", "id": "GO:0030136", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030136", "evidence": [ { "database": "UniProtKB", "id": "F1N548", "url": "https://www.uniprot.org/uniprotkb/F1N548" } ], "pmid": "" }, { "name": "presynaptic membrane", "id": "GO:0042734", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0042734", "evidence": [ { "database": "UniProtKB", "id": "F1N548", "url": "https://www.uniprot.org/uniprotkb/F1N548" } ], "pmid": "" }, { "name": "chromaffin granule membrane", "id": "GO:0042584", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0042584", "evidence": [ { "database": "UniProtKB", "id": "F1N548", "url": "https://www.uniprot.org/uniprotkb/F1N548" } ], "pmid": "" }, { "name": "excitatory synapse", "id": "GO:0060076", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0060076", "evidence": [ { "database": "UniProtKB", "id": "F1N548", "url": "https://www.uniprot.org/uniprotkb/F1N548" } ], "pmid": "" }, { "name": "Schaffer collateral - CA1 synapse", "id": "GO:0098685", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0098685", "evidence": [ { "database": "UniProtKB", "id": "F1N548", "url": "https://www.uniprot.org/uniprotkb/F1N548" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 5, "go_terms": [ { "name": "regulation of short-term neuronal synaptic plasticity", "id": "GO:0048172", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0048172", "evidence": [ { "database": "UniProtKB", "id": "F1N548", "url": "https://www.uniprot.org/uniprotkb/F1N548" } ], "pmid": "" }, { "name": "regulation of long-term neuronal synaptic plasticity", "id": "GO:0048169", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0048169", "evidence": [ { "database": "UniProtKB", "id": "F1N548", "url": "https://www.uniprot.org/uniprotkb/F1N548" } ], "pmid": "" }, { "name": "regulation of neuronal synaptic plasticity", "id": "GO:0048168", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0048168", "evidence": [ { "database": "UniProtKB", "id": "F1N548", "url": "https://www.uniprot.org/uniprotkb/F1N548" } ], "pmid": "" }, { "name": "negative regulation of exocytosis", "id": "GO:0045920", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0045920", "evidence": [ { "database": "UniProtKB", "id": "F1N548", "url": "https://www.uniprot.org/uniprotkb/F1N548" } ], "pmid": "" }, { "name": "regulation of synaptic vesicle priming", "id": "GO:0010807", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0010807", "evidence": [ { "database": "UniProtKB", "id": "F1N548", "url": "https://www.uniprot.org/uniprotkb/F1N548" } ], "pmid": "" } ] }, { "name": "Molecular Function", "total": 4, "go_terms": [ { "name": "identical protein binding", "id": "GO:0042802", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0042802", "evidence": [ { "database": "UniProtKB", "id": "F1N548", "url": "https://www.uniprot.org/uniprotkb/F1N548" } ], "pmid": "" }, { "name": "cholesterol binding", "id": "GO:0015485", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0015485", "evidence": [ { "database": "UniProtKB", "id": "F1N548", "url": "https://www.uniprot.org/uniprotkb/F1N548" } ], "pmid": "" }, { "name": "SH2 domain binding", "id": "GO:0042169", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0042169", "evidence": [ { "database": "UniProtKB", "id": "F1N548", "url": "https://www.uniprot.org/uniprotkb/F1N548" } ], "pmid": "" }, { "name": "GTPase binding", "id": "GO:0051020", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0051020", "evidence": [ { "database": "UniProtKB", "id": "F1N548", "url": "https://www.uniprot.org/uniprotkb/F1N548" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 202, "end_pos": 204, "annotation": "n_glycosylation_sequon" }, { "start_pos": 59, "end_pos": 61, "annotation": "n_glycosylation_sequon" }, { "start_pos": 99, "end_pos": 101, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "F1N548", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1N548" }, { "id": "PS51225", "database": "PROSITE", "url": "https://prosite.expasy.org/PS51225" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "MARVEL", "eco_id": "ECO_0000259", "start_pos": 21, "end_pos": 227, "start_aa": "Val", "end_aa": "Gly", "glycosite_overlap": [] } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" }, { "name": "homologset.oma", "label": 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"MGSCVSRDLLTSAHKDCPMPQGMAPLNPDLPSIVAPDHVTGKDKRMDFCWDPWQRCFQTTNGHLSDSRSCSSNYSVAALATSSLVGVVQSIKDHITKPTAMARGRVAHLIEWKGWSVQRAGWELPPAAAEEHYCLLPDELREARFAAGVAEQFAITEATLSVWSSLDDGELGLESGPVDILQLQDLGSVYLQDSLLSVRSQDDSLLAFSSPDGWPSPDEPPSPGWQLRPRLPGSLGPEAGARPQGPLRSGDGGLPSEEEDEVFYN", "length": 265, "header": "tr|G5E605-1|G5E605_BOVIN Isoform 1 of Family with sequence similarity 131 member C OS=Bos taurus OX=9913 GN=FAM131C PE=3 SV=2 CANONICAL=G5E605-1" }, "isoforms": [ { "isoform_ac": "G5E605-1", "url": "https://www.uniprot.org/uniprotkb/G5E605/entry", "sequence": { "sequence": "MGSCVSRDLLTSAHKDCPMPQGMAPLNPDLPSIVAPDHVTGKDKRMDFCWDPWQRCFQTTNGHLSDSRSCSSNYSVAALATSSLVGVVQSIKDHITKPTAMARGRVAHLIEWKGWSVQRAGWELPPAAAEEHYCLLPDELREARFAAGVAEQFAITEATLSVWSSLDDGELGLESGPVDILQLQDLGSVYLQDSLLSVRSQDDSLLAFSSPDGWPSPDEPPSPGWQLRPRLPGSLGPEAGARPQGPLRSGDGGLPSEEEDEVFYN", "length": 265, "header": "tr|G5E605-1|G5E605_BOVIN Isoform 1 of Family with sequence similarity 131 member C OS=Bos taurus OX=9913 GN=FAM131C PE=3 SV=2 CANONICAL=G5E605-1" }, "locus": { "chromosome": "2", "start_pos": 136036111, "end_pos": 136013498, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000049120.6", "url": "https://www.ensembl.org/id/ENSBTAT00000049120.6" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000046056.4", "url": "https://www.ensembl.org/id/ENSBTAP00000046056.4" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [ { "id": "bta:618019", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?bta:618019", "resource": "KEGG Pathway" } ], "orthologs": [ { "uniprot_canonical_ac": "A2ADB2-1", "protein_name": "Family with sequence similarity 131, member C", "gene_name": "Fam131c", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": 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"length": 344 }, "evidence": [ { "id": "G5E605", "url": "https://omabrowser.org/oma/group/G5E605/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "F1SUT9-1", "protein_name": "Family with sequence similarity 131 member C", "gene_name": "FAM131C", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MGSCVSRDLFTSAHKDCPMPQGTAPLSPNLPSSCPPIMAPDRVTGKDKQMDFCWDPWQRCFQTTNGYLSDSRSCSSNYNVAALATSSLVGVVQSIKDHITKPTAMARGRVAHLIEWKGWSAQRSGWELSPAEDEHYCCLPDELREARFAAGVAEQFAITEATLSAWSSLDDEELNPENSPQDVVQLQDLESIYLQDSLLSVPSQDDSLLAFSSSGLSPDGWPSPEEPPITAVGPQPPSPEQQHRQRLPGAPGPEGGAHLQGSLPSVDSGSLSEEEDEVFYN", "length": 281 }, "evidence": [ { "id": "G5E605", "url": "https://omabrowser.org/oma/group/G5E605/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "Q96AQ9-1", "protein_name": "Protein FAM131C", "gene_name": "FAM131C", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MGSCVSRDLFTSAHKNCPMPQGADPLNPDLPSGRTPTVAPDCVIGKDKQMDFCWDPWQRCFQTTNGYLSDSRSRPGNYNVAALATSSLVGVVQSIKDHITKPTAMARGRVAHLIEWKGWSAQPAGWELSPAEDEHYCCLPDELREARFAAGVAEQFAITEATLSAWSSLDEEELHPENSPQGIVQLQDLESIYLQDSLPSGPSQDDSLQAFSSPSPSPDSCPSPEEPPSTAGIPQPPSPELQHRRRLPGAQGPEGGTHPPGSLPSMDSGSLWEEDEVFYN", "length": 280 }, "evidence": [ { "id": "G5E605", "url": "https://omabrowser.org/oma/group/G5E605/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" } ], "go_annotation": {}, "pro_annotation": [], "site_annotation": [ { "start_pos": 73, "end_pos": 75, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [ { "pdb_id": "AF-G5E605-F1", "pdb_chain": "global", "start_pos": 1, "end_pos": 265, "overlap": "1.0", "method": "AlphaFold", "type": "alphafold", "resolution": -1.0, "url": "https://data.glygen.org/ln2downloads/pdb/current/AF-G5E605-F1.pdb", "url_external": "https://alphafold.ebi.ac.uk/entry/G5E605" } ], "lectin_list": [], "domain_list": [], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "homologset.oma", "label": "OMA Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 73, "end_pos": 75 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", 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{ "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ], "tool_support": { "graph_view": "yes" } }, { "uniprot_canonical_ac": "G5E637-1", "uniprot_ac": "G5E637", "uniprot_id": "G5E637_BOVIN", "mass": { "chemical_mass": 44543.0, "monoisotopic_mass": 44543.0 }, "refseq": {}, "gene_names": [ { "name": "PAG16", "type": "recommended", "evidence": [ { "id": "G5E637", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G5E637" } ] } ], "protein_names": [ { "name": "Pregnancy-associated glycoprotein 16", "type": "synonym", "evidence": [ { "id": "G5E637", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G5E637/entry#names_and_taxonomy" } ] } ], "function": [], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Bos taurus", "taxid": 9913, "evidence": [ { "database": "UniProtKB", "id": "G5E637", "url": "https://www.uniprot.org/uniprotkb/G5E637" } ], "common_name": "Bovine", "glygen_name": "Bovine", "reference_species": "Bos taurus [9913]" } ], "gene": [ { "name": "PAG16", "url": "https://www.uniprot.org/uniprotkb/G5E637", "locus": {} } ], "crossref": [ { "id": "G5E637", "url": "https://alphafold.ebi.ac.uk/entry/G5E637", "database": "AlphaFoldDB", "categories": [] }, { "id": "ENSBTAG00000047141", "url": "https://bgee.org/?page=gene&gene_id=ENSBTAG00000047141", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "IPR001461", "url": "https://www.ebi.ac.uk/interpro/entry/IPR001461", "database": 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The olfactory receptor proteins are members of a large family of G-protein-coupled receptors (GPCR) arising from single coding-exon genes. Olfactory receptors share a 7-transmembrane domain structure with many neurotransmitter and hormone receptors and are responsible for the recognition and G protein-mediated transduction of odorant signals. The olfactory receptor gene family is the largest in the genome. 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"isoform_ac": "G5E682-1", "url": "https://www.uniprot.org/uniprotkb/G5E682/entry", "sequence": { "sequence": "MTDNNHSHFQCLYFVLTGIPGLELKYYWMAFPLGAIYVIALFGNGVIISTIKSELSLHMPMYYFLCMLALADTGLALCTMPSMLGIFWFNYKSIAFDACLVQMYFIHTFSAIESGVLVAMAFDRVVAIWKPLRYGTILTNSVVCRTGAVILIRAICVVFPVPFLIKRLPFYRSNILSHSFCLHQDVMSLACASTRVNSLYGLIAVIFTKGSDSLSILLSYAFILQTVMAIASGEGQLKALSTCVSHICAVLIFYVPLIGVSVIHRFGKHLSPLTHALMANAYLLTPPVLNPIVYTMKTKEIRRKLIQIFVPAKVTAEG", "length": 318, "header": "tr|G5E682-1|G5E682_BOVIN Isoform 1 of Olfactory receptor family 51 subfamily H member 8 OS=Bos taurus OX=9913 GN=OR51H8 PE=3 SV=2 CANONICAL=G5E682-1" }, "locus": { "chromosome": "15", "start_pos": 48853405, "end_pos": 48852452, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000053983.3", "url": "https://www.ensembl.org/id/ENSBTAT00000053983.3" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000048734.3", "url": "https://www.ensembl.org/id/ENSBTAP00000048734.3" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [ { "id": "bta:527918", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?bta:527918", "resource": "KEGG Pathway" } ], "orthologs": [ { "uniprot_canonical_ac": "A0A8I6AMD8-1", "protein_name": "Olfactory receptor family 51 subfamily H member 5", "gene_name": "Or51h5", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MADHNHSQFQHLYFVLTGIPGLEQKYYWMAFPLGAIYAIALFGNGIIISTIKSESSLHIPMYYFLCMLAFADMGLTLCTLPSMLGIFWFNYKFITFDGCLVQMYFIHTFSAIESGVLVAMAIDRVIAIWSPLRYGTILTNGVVCKIGVLILSRAVCVVFPVPFLIKRLPFYRSNILSHSFCLHQDVMRLACASTRVNSLYGLIAVIFTKGSDSLSILFSYVFILRTVMAIASGEGRLKALNTCVSHICAVLIFYVPLIGVSLIHRFGKHLSPLTHALMANAYLLVPPVLNPIVYTVKTKEIRKKIIQIFIRTRISTEG", "length": 318 }, "evidence": [ { "id": "G5E682", "url": "https://omabrowser.org/oma/group/G5E682/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "F1RHR1-1", "protein_name": "G-protein coupled receptors family 1 profile domain-containing protein", "gene_name": "", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MAGNNHSHFQHLYFVLTGIPGLEQKYYWMAFPLGATYVIALLGNAVITSTIKSELSLHIPMYYFLSMLALADMGLALCTMPSVLGIFWFNYRSIAFDACLVQMYFIHTFSAIESGVLVAMAFDRVVAIWNPLRYGTILTSGVVCRTGAVILTRAVCVVFPVPFLIKRLPFYRSNLLSHSFCLHQDVMRLACASTRVNSLYGLVAVIFTKGCDSLSILFSYVFILRTVMAIAAGQGRLKALNTCVSHICAVLIFYVPLIGVSVTHRFGKHLSPLTHALMANAYLLVPPVLNPIVYAVKTKEIRRKLIEMFVQTKITAGG", "length": 318 }, "evidence": [ { "id": "G5E682", "url": "https://omabrowser.org/oma/group/G5E682/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "Q8VGZ3-1", "protein_name": "Olfactory receptor family 51 subfamily H member 5", "gene_name": "Or51h5", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MADHNHSQSQHLYFILTGIPGLEQKYYWMAFPLGAIYVIALFGNGVIISTIKSESSLHIPMYYFLCMLAFADMGLTLCTLPSMLGIFWFNYKFITFDGCLVQMYFIHTFSAIESGVLVAMAIDRVIAIWSPLRYGTILTNGVVCKIGMLILSRAVCVVFPVPFLIKRLPFYRSNILSHSFCLHQDVMRLACASTRVNSLYGLIAVIFTKGSDSLSILISYVFILRTVMAIASGEGRLKALNTCVSHICAVLIFYVPLIGVSVIHRFGKHLSPLTHALMANAYLLVPPVLNPIVYTVKTKEIRKKIIQIFIRTKITTEG", "length": 318 }, "evidence": [ { "id": "G5E682", "url": "https://omabrowser.org/oma/group/G5E682/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" } ], "go_annotation": { "categories": [ { "name": "Molecular Function", "total": 2, "go_terms": [ { "name": "G protein-coupled receptor activity", "id": "GO:0004930", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0004930", "evidence": [ { "database": "UniProtKB", "id": "G5E682", "url": "https://www.uniprot.org/uniprotkb/G5E682" } ], "pmid": "" }, { "name": "olfactory receptor activity", "id": "GO:0004984", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0004984", "evidence": [ { "database": "UniProtKB", "id": "G5E682", "url": "https://www.uniprot.org/uniprotkb/G5E682" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 1, "go_terms": [ { "name": "plasma membrane", "id": "GO:0005886", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005886", "evidence": [ { "database": "UniProtKB", "id": "G5E682", "url": "https://www.uniprot.org/uniprotkb/G5E682" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 1, "go_terms": [ { "name": "cellular response to lipid", "id": "GO:0071396", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0071396", "evidence": [ { "database": "UniProtKB", "id": "G5E682", "url": "https://www.uniprot.org/uniprotkb/G5E682" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 5, "end_pos": 7, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [ { "pdb_id": "AF-G5E682-F1", "pdb_chain": "global", "start_pos": 1, "end_pos": 318, "overlap": "1.0", "method": "AlphaFold", "type": "alphafold", "resolution": -1.0, "url": "https://data.glygen.org/ln2downloads/pdb/current/AF-G5E682-F1.pdb", "url_external": "https://alphafold.ebi.ac.uk/entry/G5E682" } ], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "G5E682", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G5E682" }, { "id": "PS50262", "database": "PROSITE", "url": "https://prosite.expasy.org/PS50262" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "G-protein coupled receptors family 1 profile", "eco_id": "ECO_0000259", "start_pos": 43, "end_pos": 294, "start_aa": "Gly", "end_aa": "Tyr", "glycosite_overlap": [] } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "homologset.oma", "label": "OMA Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 5, "end_pos": 7 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ], "tool_support": { "graph_view": "yes" } }, { "uniprot_canonical_ac": "G5E6A2-1", "uniprot_ac": "G5E6A2", "uniprot_id": "G5E6A2_BOVIN", "mass": { "chemical_mass": 31307.0, "monoisotopic_mass": 31307.0 }, "refseq": {}, "gene_names": [ { "name": "OR52Z19", "type": "recommended", "evidence": [ { "id": "G5E6A2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G5E6A2" } ] } ], "protein_names": [ { "name": "Olfactory receptor family 52 subfamily Z member 19", "type": "synonym", "evidence": [ { "id": "G5E6A2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G5E6A2/entry#names_and_taxonomy" } ] } ], "function": [ { "annotation": "Odorant receptor.", "evidence": [ { "database": "UniProtKB", "id": "G5E6A2", "url": "https://www.uniprot.org/uniprotkb/G5E6A2#function" }, { "database": "UniProtKB", "id": "ARBA00002936", "url": "https://www.uniprot.org/uniprotkb/ARBA00002936#function" } ] }, { "annotation": "Putative odorant or sperm cell receptor.", "evidence": [ { "database": "UniProtKB", "id": "G5E6A2", "url": "https://www.uniprot.org/uniprotkb/G5E6A2#function" }, { "database": "UniProtKB", "id": "ARBA00003929", "url": "https://www.uniprot.org/uniprotkb/ARBA00003929#function" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Bos taurus", "taxid": 9913, "evidence": [ { "database": "UniProtKB", "id": "G5E6A2", "url": "https://www.uniprot.org/uniprotkb/G5E6A2" } ], "common_name": "Bovine", "glygen_name": "Bovine", "reference_species": "Bos taurus [9913]" } ], "gene": [ { "name": "OR52Z19", "url": "https://www.uniprot.org/uniprotkb/G5E6A2", "locus": { "chromosome": "15", "start_pos": 49589211, "end_pos": 49588366, "strand": "-", "evidence": [ { "database": "Ensembl Gene", "id": "ENSBTAG00000047479", "url": "https://www.ensembl.org/id/ENSBTAG00000047479" } ] } } ], "crossref": [ { "id": "G5E6A2", "url": "https://alphafold.ebi.ac.uk/entry/G5E6A2", "database": "AlphaFoldDB", "categories": [] }, { "id": "ENSBTAG00000047479", "url": "https://bgee.org/?page=gene&gene_id=ENSBTAG00000047479", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "IPR000276", "url": "https://www.ebi.ac.uk/interpro/entry/IPR000276", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR000725", "url": "https://www.ebi.ac.uk/interpro/entry/IPR000725", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR017452", "url": "https://www.ebi.ac.uk/interpro/entry/IPR017452", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR050402", "url": "https://www.ebi.ac.uk/interpro/entry/IPR050402", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "G5E6A2", "url": "https://www.orthodb.org/?gene=G5E6A2", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR26450", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR26450", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR26450:SF17", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR26450:SF17", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF13853", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF13853", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "G5E6A2", "url": "https://www.uniprot.org/uniprotkb/G5E6A2", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "G5E6A2-1", "url": "https://www.uniprot.org/uniprotkb/G5E6A2-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MTGVPGLEDFHIWISIPFSFMYHLAVTGNGLVMVMVIWDRSLHEPMYLFLAILALNHVLLCTVTVPKMLLIFWQGPSISTFSACLTQMFYVHALSESAVLLAMAFDHYVAICAPLHYTTLLTGSLMSKMVLALVARSVAVVTPGILLILRLHFCRSNIIHHTYCENMGIAKLACYSIVPNSIYGLTAALLTTGLDLVPISLSYWLILRTVLRLPSREARTKASGTCGAHACVLLIFYTLAFFSSFTHRFGHHAPRHVLILLANLYLLVPPTMNPIVYGVKTK", "length": 282, "header": "tr|G5E6A2-1|G5E6A2_BOVIN Isoform 1 of Olfactory receptor family 52 subfamily Z member 19 OS=Bos taurus OX=9913 GN=OR52Z19 PE=3 SV=4 CANONICAL=G5E6A2-1" }, "isoforms": [ { "isoform_ac": "G5E6A2-1", "url": "https://www.uniprot.org/uniprotkb/G5E6A2/entry", "sequence": { "sequence": "MTGVPGLEDFHIWISIPFSFMYHLAVTGNGLVMVMVIWDRSLHEPMYLFLAILALNHVLLCTVTVPKMLLIFWQGPSISTFSACLTQMFYVHALSESAVLLAMAFDHYVAICAPLHYTTLLTGSLMSKMVLALVARSVAVVTPGILLILRLHFCRSNIIHHTYCENMGIAKLACYSIVPNSIYGLTAALLTTGLDLVPISLSYWLILRTVLRLPSREARTKASGTCGAHACVLLIFYTLAFFSSFTHRFGHHAPRHVLILLANLYLLVPPTMNPIVYGVKTK", "length": 282, "header": "tr|G5E6A2-1|G5E6A2_BOVIN Isoform 1 of Olfactory receptor family 52 subfamily Z member 19 OS=Bos taurus OX=9913 GN=OR52Z19 PE=3 SV=4 CANONICAL=G5E6A2-1" }, "locus": { "chromosome": "15", "start_pos": 49589211, "end_pos": 49588366, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000056313.4", "url": "https://www.ensembl.org/id/ENSBTAT00000056313.4" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000049696.4", "url": "https://www.ensembl.org/id/ENSBTAP00000049696.4" } ] } } ], "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "other", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 142, "start_aa": "Thr", "end_pos": 142, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr142", "evidence": [ { "id": "", "database": "GlyGen", "url": "https://data.glygen.org/" } ], "filter_code": "000000000000000010000.00000000001000.0.01000" } ], "phosphorylation": [], "glycation": [], "keywords": [ "glycoprotein", "glycoprotein_predicted" ], "publication": [], "pathway": [], "orthologs": [], "go_annotation": { "categories": [ { "name": "Molecular Function", "total": 2, "go_terms": [ { "name": "G protein-coupled receptor activity", "id": "GO:0004930", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0004930", "evidence": [ { "database": "UniProtKB", "id": "G5E6A2", "url": "https://www.uniprot.org/uniprotkb/G5E6A2" } ], "pmid": "" }, { "name": "olfactory receptor activity", "id": "GO:0004984", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0004984", "evidence": [ { "database": "UniProtKB", "id": "G5E6A2", "url": "https://www.uniprot.org/uniprotkb/G5E6A2" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 1, "go_terms": [ { "name": "plasma membrane", "id": "GO:0005886", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005886", "evidence": [ { "database": "UniProtKB", 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The olfactory receptor proteins are members of a large family of G-protein-coupled receptors (GPCR) arising from single coding-exon genes. Olfactory receptors share a 7-transmembrane domain structure with many neurotransmitter and hormone receptors and are responsible for the recognition and G protein-mediated transduction of odorant signals. The olfactory receptor gene family is the largest in the genome. 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The olfactory receptor proteins are members of a large family of G-protein-coupled receptors (GPCR) arising from single coding-exon genes. Olfactory receptors share a 7-transmembrane domain structure with many neurotransmitter and hormone receptors and are responsible for the recognition and G protein-mediated transduction of odorant signals. The olfactory receptor gene family is the largest in the genome. [provided by RefSeq, Jul 2008].", "evidence": [ { "database": "RefSeq", "id": "NP_001376725", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001376725" } ] }, { "annotation": "Putative odorant or sperm cell receptor.", "evidence": [ { "database": "UniProtKB", "id": "G5E6K5", "url": "https://www.uniprot.org/uniprotkb/G5E6K5#function" }, { "database": "UniProtKB", "id": "ARBA00003929", "url": "https://www.uniprot.org/uniprotkb/ARBA00003929#function" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Bos taurus", "taxid": 9913, "evidence": [ { "database": "UniProtKB", "id": "G5E6K5", "url": "https://www.uniprot.org/uniprotkb/G5E6K5" } ], "common_name": "Bovine", "glygen_name": "Bovine", "reference_species": "Bos taurus [9913]" } ], "gene": [ { "name": "OR10G1C", "url": "https://www.uniprot.org/uniprotkb/G5E6K5", "locus": { "chromosome": "10", "start_pos": 25587963, "end_pos": 25587007, "strand": "-", "evidence": [ { "database": "Ensembl Gene", "id": "ENSBTAG00000060452", "url": "https://www.ensembl.org/id/ENSBTAG00000060452" } ] } } ], "crossref": [ { "id": "G5E6K5", "url": "https://alphafold.ebi.ac.uk/entry/G5E6K5", "database": "AlphaFoldDB", "categories": [] }, { "id": "ENSBTAG00000055093", "url": "https://bgee.org/?page=gene&gene_id=ENSBTAG00000055093", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "cd15916", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd15916", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "507759", "url": "https://www.ncbi.nlm.nih.gov/gene/507759", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR000276", "url": "https://www.ebi.ac.uk/interpro/entry/IPR000276", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR000725", "url": "https://www.ebi.ac.uk/interpro/entry/IPR000725", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR017452", "url": "https://www.ebi.ac.uk/interpro/entry/IPR017452", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "bta:507759", "url": "https://www.genome.jp/dbget-bin/www_bget?bta:507759", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "QLNARPM", "url": "https://omabrowser.org/oma/group/QLNARPM/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "G5E6K5", "url": "https://www.orthodb.org/?gene=G5E6K5", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR26453", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR26453", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF13853", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF13853", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "NP_001376725", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001376725", 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"id": "G5E6N2", "url": "https://alphafold.ebi.ac.uk/entry/G5E6N2", "database": "AlphaFoldDB", "categories": [] }, { "id": "ENSBTAG00000047482", "url": "https://bgee.org/?page=gene&gene_id=ENSBTAG00000047482", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "100335204", "url": "https://www.ncbi.nlm.nih.gov/gene/100335204", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR052836", "url": "https://www.ebi.ac.uk/interpro/entry/IPR052836", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR059081", "url": "https://www.ebi.ac.uk/interpro/entry/IPR059081", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "bta:100335204", "url": "https://www.genome.jp/dbget-bin/www_bget?bta:100335204", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "ARCWAKL", "url": "https://omabrowser.org/oma/group/ARCWAKL/", "database": "OMA", "categories": [ "Protein Classification" ] }, { 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[ "Protein" ] } ], "sequence": { "sequence": "MAGYGYLGLGLFCWVLLAVPVGPQPASSVPGAPLTTLNPPPQSEASMLSLNLGLNFKFHLRGPAAVWGNPVTETQALSPRPSREPKEEAASGLRTDPLWELLVGSLGNSPPEWGSAEGSSTSWASSPALESASLLSGPADGPTAPYRPGMGTVTWNTALTATAPPSSAPRLRQSELELKFDVALRAGAAPTLGHRTLPLLPSLRASLAEIAGRLGPFGFFGTTVSPLRNLSGPSPPGPITSPGSASGVSDSPGFFGTTLSPPPSPQERKLPSPRPLDPAASLSSALIATASLESTTPTSGLDDPSPASLGNLSVQPECGPGSCSIRELPESEGQPPAAPLPLFFLTLEADWAEAKARWGLAWEAHVYGVGALFGLVALLALLALALLPWRCPPGAPCLALLDMLLLSAGTTRAFPLFYDAYGHRDRLPALAWLLLQDLPLPCLAAGLGLACLLLARPRPPRCPAGLAALLLLGLGLAAAAALGSAAHRPLRALRLASRGLHAFLAALLSGLLLALSCLGGRRRRAGAPLGAAGFKGATPLPQARSPFGPRESWRRAARTAPVAGTFGLLSGALQGYEVLHALGYGGQPGLEGPWPWWAFQLGLRLGEVGVALPLALLGLYPALCSPRVPPRCWAKLFRLSPGHAAPLLPGGWVTGAPDKKPLGSAIARGDAELLQLCALAGPGPDLLLQGGGCRSFDGAAAHPAPSPASSPCSDDTVDFRPPSPINLRRSIEEALCSEALLAPGLFQVPAFGEALPSLGVYRTASLGAQTGVGPIGRSGEAPGSPAPRELPSPGTWPAGSSASSGSLCGLSRDSSSVLLCSSPDRAPRCPLVCVLSPPRPSGSSPSLPASGSYQALSPPSRDSPEPAPELQAEEALLQEQFLDACRQIDELSMGSDTIDL", "length": 900, "header": "tr|G5E6N2-1|G5E6N2_BOVIN Isoform 1 of Proline rich transmembrane protein 4 OS=Bos taurus OX=9913 GN=PRRT4 PE=4 SV=2 CANONICAL=G5E6N2-1" }, "isoforms": [ { "isoform_ac": "G5E6N2-1", "url": "https://www.uniprot.org/uniprotkb/G5E6N2/entry", "sequence": { "sequence": "MAGYGYLGLGLFCWVLLAVPVGPQPASSVPGAPLTTLNPPPQSEASMLSLNLGLNFKFHLRGPAAVWGNPVTETQALSPRPSREPKEEAASGLRTDPLWELLVGSLGNSPPEWGSAEGSSTSWASSPALESASLLSGPADGPTAPYRPGMGTVTWNTALTATAPPSSAPRLRQSELELKFDVALRAGAAPTLGHRTLPLLPSLRASLAEIAGRLGPFGFFGTTVSPLRNLSGPSPPGPITSPGSASGVSDSPGFFGTTLSPPPSPQERKLPSPRPLDPAASLSSALIATASLESTTPTSGLDDPSPASLGNLSVQPECGPGSCSIRELPESEGQPPAAPLPLFFLTLEADWAEAKARWGLAWEAHVYGVGALFGLVALLALLALALLPWRCPPGAPCLALLDMLLLSAGTTRAFPLFYDAYGHRDRLPALAWLLLQDLPLPCLAAGLGLACLLLARPRPPRCPAGLAALLLLGLGLAAAAALGSAAHRPLRALRLASRGLHAFLAALLSGLLLALSCLGGRRRRAGAPLGAAGFKGATPLPQARSPFGPRESWRRAARTAPVAGTFGLLSGALQGYEVLHALGYGGQPGLEGPWPWWAFQLGLRLGEVGVALPLALLGLYPALCSPRVPPRCWAKLFRLSPGHAAPLLPGGWVTGAPDKKPLGSAIARGDAELLQLCALAGPGPDLLLQGGGCRSFDGAAAHPAPSPASSPCSDDTVDFRPPSPINLRRSIEEALCSEALLAPGLFQVPAFGEALPSLGVYRTASLGAQTGVGPIGRSGEAPGSPAPRELPSPGTWPAGSSASSGSLCGLSRDSSSVLLCSSPDRAPRCPLVCVLSPPRPSGSSPSLPASGSYQALSPPSRDSPEPAPELQAEEALLQEQFLDACRQIDELSMGSDTIDL", "length": 900, "header": "tr|G5E6N2-1|G5E6N2_BOVIN Isoform 1 of Proline rich transmembrane protein 4 OS=Bos taurus OX=9913 GN=PRRT4 PE=4 SV=2 CANONICAL=G5E6N2-1" }, "locus": { "chromosome": "4", "start_pos": 92545269, "end_pos": 92537254, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000063432.3", "url": "https://www.ensembl.org/id/ENSBTAT00000063432.3" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000056376.2", "url": "https://www.ensembl.org/id/ENSBTAP00000056376.2" } ] } } ], "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "other", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 143, "start_aa": "Thr", "end_pos": 143, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr143", "evidence": [ { "id": "", "database": "GlyGen", "url": "https://data.glygen.org/" } ], "filter_code": "000000000000000010000.00000000001000.0.01000" } ], "phosphorylation": [], "glycation": [], "keywords": [ "glycoprotein", "glycoprotein_predicted" ], "publication": [], "pathway": [ { "id": "bta:100335204", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?bta:100335204", "resource": "KEGG Pathway" } ], "orthologs": [ { "uniprot_canonical_ac": "B2RU40-1", "protein_name": "Proline-rich transmembrane protein 4", "gene_name": "Prrt4", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MAGRSCLELGLFCWVLLAVPVGPQPASSVPGAPLTTLTPPPQSEASMLSLNLGLNFKFHLRGPAAVWGNPVTETHPLSPGLGQESEEEEEGDLRTDPLWELLVGSPGNYLPEWGSAEGSFTPWASSLPPESTSRLSGPTKRPTAHSQPRMGTVTWATALTATAPPTSAPRPHQSELELKFDVALRAGAAPTLGHRSLPLLPSLRASLAEIAGRLGPFGFFGTTVSPLRNFSRQSYPGTTAHPSFAFEVSDSPGLFGTTGSRPPPLLERKFSSPSLLDSVASPSSASVKTTPVQQDPTVSTSGPDELSPASFGNPSTQPGCEPGSCSEPELLDDLGQPPASPLPLFFLTLEADWAEARARWGLAWEAHVYGAGALFGLVALLALLALALLPWRCPPGAPCLALLDLLLLSAGTTRAFPLFYDAYGHRDRLPTLVWLLLQDLPLPCLAAGLGLACLLLARPRTPRCPAGLAALLLLGLGLAAAAALGSAVHRPLRPLRLASRGLHAFLAAFLSGLLLALSCWGGRRRRAGAPLGGAGFKGATPVPQVRSPFAPRESWRRAARTAPVAGTFGLLSGALQGYEVLHALGYGSQAGLEGPWPWWAFQLGLRLGEVGVALPLALLGLYPALCSPRVPRRCWAKLFRLSPGHAAPLLPGGWVPGIPDKEPLGSAIARGDAELLQLCALAGPGPDLLLQGGGCRGFEGAGANPTQSTASSPSSDCTVDFRPPSPINLRRSIEEALCSEALLAPGLFQGPAFGEALPGLGLYRTISLGNKIGAGPSEKSENVPGSPAPPELPSPGAWPPGSSASSGSLCGLSRDSSSMLLCSSPDRPPRCPLVCVLSPPRPSESSPSLPASGSYQALSPPSRDSPEHASELQAEEALLQEQFLDACRQIDELSMGSDTIDL", "length": 902 }, "evidence": [ { "id": "G5E6N2", "url": "https://omabrowser.org/oma/group/G5E6N2/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "C9JH25-1", "protein_name": "Proline-rich transmembrane protein 4", "gene_name": "PRRT4", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MARHGCLGLGLFCCVLFAATVGPQPTPSIPGAPATTLTPVPQSEASMLSLNLGLNFKFHLRGPAAVWGSPVTETQPLSLGPGQEPGEEVASGLRTDPLWELLVGSSGNSLTEWGSTEGGSKPRASSLLPESTSRRSGPSDGPTAPYQPRRSTVTWDTALMVTALPSSAPRPHQSELELKFDMALRAGAAPTLGHRTLPLLPSLRASLAEIAGRLGPFGFFGTTLSPLRNFSGLSPPGETTSTSSASGVSGSLGFLGTTLSLPPYSLERKLSSPSPLDPAASLSFASIATTSLDPTVPISGPDDLSPPASLGNPSGQPECGPGSCSVGELPEREGQPPEAPRPLFFLTLEADWAEARARWGLAWEAHVYGVGALFGLVALLALLALALLPWRCPPGAPCLALLDLLLLSAGTTRAFPLFYDAYGHRDRLPALAWLLLQDLPLPCLAAGLGLACLLLARPRPPRCPTGLAALLLLGLGLAAAAALGSAAHRPLRPLRLASRGLHAFLAAFLSGLLLALSCWGGRRRRAGAPLGGSGFKGATPLPQGRSPFAPRESWRRAARTAPVAGTFGLLSGALQGYEVLHALGYGGQSGLEGPWPWWAFQLGLRLGEVGVALPLALLGLYPALCSPRVPPRCWAKLFRLSPGHAAPLLPGGWVTGPPDKEPLGSAIARGDAELLQLCALAGPGPDLLLQGGGCRGFEGAAANPAPSPASSPCSDYTVDFRPPSPINLRRSIEEALCSEALLAPGLFQGPAFEDALPGLGLYRTASLGTGGRASERSGEASGPAAPPELPSPGAWPAGSSVSSGSFCGLSRDSSSMLLCSSPDRPPRCPLVCVLSPPRPSGSSPSLPASGSYQALSPPSRDSPEPASELQAEEALLQEQFLDACRQIDELSVGSDTIDL", "length": 899 }, "evidence": [ { "id": "G5E6N2", "url": "https://omabrowser.org/oma/group/G5E6N2/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "D4A9R4-1", "protein_name": "Proline-rich transmembrane protein 4", "gene_name": "Prrt4", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MAGRGCLELGLFCWVLLAVPVGPQPASSVPGAPLTTLTPPPQSEASMLSLNLGLNFKFHLRGPAAVWGSPVTETHPLSPGLGQESEEDLEGDLRTDPLWELLVGSPGNYVPEWGSAEGSFTPWASSLPPESTSPLSGPTKRPTAPSQPRMSTVTWATALTATAPPTSAPRPRQSELELKFDVALRAGAAPTLGHRSLPLLPSLRASLAEIAGRLGPFGFFGTTLSPLRNFSSQSYQGTTAQPSFASEVSDFPGLFGTTGSLPPPLLERKFSSPSPLDSVASPSSASIKTTPVQHDPTVSTSDPDELSPASFGSPSAQPGCEPGSCSEPELSDDSGQPPASPLPLFFLTLEADWAEARARWGLAWEAHVYGAGALFGLVALLALLSLALLPWRCPPGAPCLALLDLLLLSAGTTRAFPLFYDAYGHRDRLPALAWLLLQDLPLPCLAAGLGLACLLLARPRTPRCPIGLAALLLLGLGLAAAAALGSAVHRPLRPLRLASRGLHAFLAAFLSGLLLALSCWGGRRRRAGAPLGGSGFKGATPVPQVRSPFAPRESWRRAARTAPVAGTFGLLSGALQGYEVLHALGYGGQTGLEGPWPWWAFQLGLRLGEVGVALPLALLGLYPALCSPRVPRRCWAKLFRLSPGHAAPLLPGGWVPGIRDKEPLGSAIARGDAELLQLCALAGPGPDLLLQGGSCPGFEGARANTTQSPASSPSSDCTVDFRPPSPINLRRSIEEALCSEALLAPGLFQGPAFGDALSGLGLYRTISLGNKTGAGPSEKSEKVPGSPAPPELPSPGAWPPGSSASSGSLCGLSRDSSSMLLCSSPDRPPRCPLVCVLSPPRPSESSPSLPASGSYQALSPPSRDSPEHASELQAEEALLQEQFLDACRQIDELSMGSDTIDL", "length": 902 }, "evidence": [ { "id": "G5E6N2", "url": "https://omabrowser.org/oma/group/G5E6N2/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" } ], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 1, "go_terms": [ { "name": "membrane", "id": "GO:0016020", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016020", "evidence": [ { "database": "UniProtKB", "id": "G5E6N2", "url": "https://www.uniprot.org/uniprotkb/G5E6N2" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 229, "end_pos": 231, "annotation": "n_glycosylation_sequon" }, { "start_pos": 311, "end_pos": 313, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [ { "pdb_id": "AF-G5E6N2-F1", "pdb_chain": "global", "start_pos": 1, "end_pos": 900, "overlap": "1.0", "method": "AlphaFold", "type": "alphafold", "resolution": -1.0, "url": "https://data.glygen.org/ln2downloads/pdb/current/AF-G5E6N2-F1.pdb", "url_external": "https://alphafold.ebi.ac.uk/entry/G5E6N2" } ], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "G5E6N2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G5E6N2" }, { "id": "PF25987", "database": "Pfam", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF25987" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "Proline-rich transmembrane protein 3/4", "eco_id": "ECO_0000259", "start_pos": 350, "end_pos": 639, "start_aa": "Asp", "end_aa": "Leu", "glycosite_overlap": [] } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "homologset.oma", "label": "OMA Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [ 143 ], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 229, "end_pos": 231 }, { "start_pos": 311, "end_pos": 313 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 1 }, { "field": "total_sites", "count": 1 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 1 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "exact_sites", "count": 1 }, { "field": "exact_o_linked_sites", "count": 1 }, { "field": "fuzzy_sites", "count": 0 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_pos", "start_aa", "end_pos", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 1 }, { "field": "total_sites", "count": 1 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 1 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "exact_sites", "count": 1 }, { "field": "exact_o_linked_sites", "count": 1 }, { "field": "fuzzy_sites", "count": 0 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_pos", "start_aa", "end_pos", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ], "tool_support": { "graph_view": "yes" } }, { "uniprot_canonical_ac": "G5E6P6-1", "uniprot_ac": "G5E6P6", "uniprot_id": "G5E6P6_BOVIN", "mass": { "chemical_mass": 8994.0, "monoisotopic_mass": 8994.0 }, "refseq": { "ac": "NP_001231493", "name": "cortexin-2", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001231493" }, "gene_names": [ { "name": "CTXN2", "type": "recommended", "evidence": [ { "id": "G5E6P6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G5E6P6" } ] }, { "name": "CTXN2", "type": "synonym", "evidence": [ { "id": "NP_001231493", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001231493" } ] } ], "protein_names": [ { "name": "Cortexin 2", "type": "synonym", "evidence": [ { "id": "G5E6P6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G5E6P6/entry#names_and_taxonomy" } ] }, { "name": "cortexin-2", "type": "synonym", "evidence": [ { "id": "NP_001231493", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001231493" } ] } ], "function": [], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Bos taurus", "taxid": 9913, "evidence": [ { "database": "UniProtKB", "id": "G5E6P6", "url": "https://www.uniprot.org/uniprotkb/G5E6P6" } ], "common_name": "Bovine", "glygen_name": "Bovine", "reference_species": "Bos taurus [9913]" } ], "gene": [ { "name": "CTXN2", "url": "https://www.uniprot.org/uniprotkb/G5E6P6", "locus": { "chromosome": "10", "start_pos": 62185988, "end_pos": 62192924, "strand": "+", "evidence": [ { "database": "Ensembl Gene", "id": "ENSBTAG00000045847", "url": "https://www.ensembl.org/id/ENSBTAG00000045847" } ] } } ], "crossref": [ { "id": "G5E6P6", "url": "https://alphafold.ebi.ac.uk/entry/G5E6P6", "database": "AlphaFoldDB", "categories": [] }, { "id": "ENSBTAG00000045847", "url": "https://bgee.org/?page=gene&gene_id=ENSBTAG00000045847", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "100336358", "url": "https://www.ncbi.nlm.nih.gov/gene/100336358", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR020066", "url": "https://www.ebi.ac.uk/interpro/entry/IPR020066", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "bta:100336358", "url": "https://www.genome.jp/dbget-bin/www_bget?bta:100336358", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "GNDIMAH", "url": "https://omabrowser.org/oma/group/GNDIMAH/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "G5E6P6", "url": "https://www.orthodb.org/?gene=G5E6P6", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR16736", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR16736", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR16736:SF2", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR16736:SF2", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF11057", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF11057", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "NP_001231493", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001231493", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "G5E6P6", "url": 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"https://www.uniprot.org/uniprotkb/H2L2P1" } ], "pmid": "" }, { "name": "positive regulation of developmental growth", "id": "GO:0048639", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0048639", "evidence": [ { "database": "UniProtKB", "id": "H2L2P1", "url": "https://www.uniprot.org/uniprotkb/H2L2P1" } ], "pmid": "" }, { "name": "positive regulation of TOR signaling", "id": "GO:0032008", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0032008", "evidence": [ { "database": "UniProtKB", "id": "H2L2P1", "url": "https://www.uniprot.org/uniprotkb/H2L2P1" } ], "pmid": "" }, { "name": "positive regulation of tumor necrosis factor production", "id": "GO:0032760", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0032760", "evidence": [ { "database": "UniProtKB", "id": "H2L2P1", "url": "https://www.uniprot.org/uniprotkb/H2L2P1" } ], "pmid": "" }, { "name": "positive regulation of p38MAPK cascade", "id": "GO:1900745", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:1900745", "evidence": [ { "database": "UniProtKB", "id": "H2L2P1", "url": "https://www.uniprot.org/uniprotkb/H2L2P1" } ], "pmid": "" }, { "name": "positive regulation of interleukin-8 production", "id": "GO:0032757", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0032757", "evidence": [ { "database": "UniProtKB", "id": "H2L2P1", "url": "https://www.uniprot.org/uniprotkb/H2L2P1" } ], "pmid": "" }, { "name": "regulation of angiogenesis", "id": "GO:0045765", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0045765", "evidence": [ { "database": "UniProtKB", "id": "H2L2P1", "url": "https://www.uniprot.org/uniprotkb/H2L2P1" } ], "pmid": "" }, { "name": "positive regulation of receptor signaling pathway via JAK-STAT", "id": "GO:0046427", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0046427", "evidence": [ { "database": "UniProtKB", "id": "H2L2P1", "url": "https://www.uniprot.org/uniprotkb/H2L2P1" } ], "pmid": "" }, { "name": "positive regulation of T cell proliferation", "id": "GO:0042102", "url": 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(16-20)-hydroxyeicosatetraenoic acids (HETE)" } ], "orthologs": [ { "uniprot_canonical_ac": "P51869-1", "protein_name": "Cytochrome P450 4F4", "gene_name": "Cyp4f4", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MPQLDLSWLGLRLETSLPWLLLLLIGASWLLVRVLTQTYIFYRTYQHLCDFPQPPKWNWFLGHLGMITPTEQGLKQVTKLVATYPQGFMTWLGPILPIITLCHPDVIRSVLSASASVALKEVIFYSFLKPWLGDGLLLSDGDKWSCHRRMLTPAFHFNILKPYVKIFNDSTNIMHAKWQDLASGGSARLDMFKNISLMTLDSLQKCVFSFDSNCQEKPSEYISAILELSALVAKRYQQLLLHTDSLYQLTHNGRRFHKACKLVHNFTDAVIQGRRRALPSQHEDDILKAKARSKTLDFIDVLLLTKDEDGKELSDEDIRAEADTFMFEGHDTTASGLSWILYNLARHPEYQERCRQEVRELLRDRESTEIEWDDLAQLPFLTMCIKESLRLHPPVTVISRRCTQDIVLPDGRVIPKGVICIINIFATHHNPTVWPDPEVYDPFRFDPENIKDRSPLAFIPFSAGPRNCIGQTFAMNEMKVALALTLLRFRVLPDDKEPRRKPELILRAEGGLWLRVEPLSTQ", "length": 522 }, "evidence": [ { "id": "M0QW30", "url": "https://omabrowser.org/oma/group/M0QW30/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "Q08477-1", "protein_name": "Cytochrome P450 4F3", "gene_name": "CYP4F3", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MPQLSLSSLGLWPMAASPWLLLLLVGASWLLARILAWTYTFYDNCCRLRCFPQPPKRNWFLGHLGLIHSSEEGLLYTQSLACTFGDMCCWWVGPWHAIVRIFHPTYIKPVLFAPAAIVPKDKVFYSFLKPWLGDGLLLSAGEKWSRHRRMLTPAFHFNILKPYMKIFNESVNIMHAKWQLLASEGSARLDMFEHISLMTLDSLQKCVFSFDSHCQEKPSEYIAAILELSALVTKRHQQILLYIDFLYYLTPDGQRFRRACRLVHDFTDAVIQERRRTLPSQGVDDFLQAKAKSKTLDFIDVLLLSKDEDGKKLSDEDIRAEADTFMFEGHDTTASGLSWVLYHLAKHPEYQERCRQEVQELLKDREPKEIEWDDLAQLPFLTMCIKESLRLHPPVPAVSRCCTQDIVLPDGRVIPKGIICLISVFGTHHNPAVWPDPEVYDPFRFDPKNIKERSPLAFIPFSAGPRNCIGQAFAMAEMKVVLGLTLLRFRVLPDHTEPRRKPELVLRAEGGLWLRVEPLS", "length": 520 }, "evidence": [ { "id": "M0QW30", "url": "https://omabrowser.org/oma/group/M0QW30/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "Q9ZW95-1", "protein_name": "Cytokinin hydroxylase", "gene_name": "CYP735A2", "tax_id": 3702, "organism": "Arabidopsis thaliana", "sequence": { "sequence": "MMVTLVLKYVLVIVMTLILRVLYDSICCYFLTPRRIKKFMERQGITGPKPRLLTGNIIDISKMLSHSASNDCSSIHHNIVPRLLPHYVSWSKQYGKRFIMWNGTEPRLCLTETEMIKELLTKHNPVTGKSWLQQQGTKGFIGRGLLMANGEAWHHQRHMAAPAFTRDRLKGYAKHMVECTKMMAERLRKEVGEEVEIGEEMRRLTADIISRTEFGSSCDKGKELFSLLTVLQRLCAQATRHLCFPGSRFLPSKYNREIKSLKTEVERLLMEIIDSRKDSVEIGRSSSYGDDLLGLLLNQMDSNKNNLNVQMIMDECKTFFFTGHETTSLLLTWTLMLLAHNPTWQDNVRDEVRQVCGQDGVPSVEQLSSLTSLNKVINESLRLYPPATLLPRMAFEDIKLGDLIIPKGLSIWIPVLAIHHSNELWGEDANEFNPERFTTRSFASSRHFMPFAAGPRNCIGQTFAMMEAKIILAMLVSKFSFAISENYRHAPIVVLTIKPKYGVQLVLKPLDL", "length": 512 }, "evidence": [ { "id": "M0QW30", "url": "https://omabrowser.org/oma/group/M0QW30/", "database": "OMA" } ], "glygen_name": "Arabidopsis", "common_name": "Mouse-ear cress" } ], "go_annotation": { "categories": [ { "name": "Molecular Function", "total": 4, "go_terms": [ { "name": "iron ion binding", "id": "GO:0005506", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005506", "evidence": [ { "database": "UniProtKB", "id": "M0QW30", "url": 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"https://www.ebi.ac.uk/QuickGO/term/GO:0005789", "evidence": [ { "database": "UniProtKB", "id": "M0QW30", "url": "https://www.uniprot.org/uniprotkb/M0QW30" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 1, "go_terms": [ { "name": "small molecule metabolic process", "id": "GO:0044281", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0044281", "evidence": [ { "database": "UniProtKB", "id": "M0QW30", "url": "https://www.uniprot.org/uniprotkb/M0QW30" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 112, "end_pos": 114, "annotation": "n_glycosylation_sequon" }, { "start_pos": 43, "end_pos": 45, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [ { "pdb_id": "AF-M0QW30-F1", "pdb_chain": "global", "start_pos": 1, "end_pos": 524, "overlap": "1.0", "method": "AlphaFold", "type": "alphafold", "resolution": -1.0, "url": "https://data.glygen.org/ln2downloads/pdb/current/AF-M0QW30-F1.pdb", "url_external": "https://alphafold.ebi.ac.uk/entry/M0QW30" } ], "lectin_list": [], "domain_list": [], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "homologset.oma", "label": "OMA Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 112, "end_pos": 114 }, { "start_pos": 43, "end_pos": 45 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ], "tool_support": { "graph_view": "yes" } }, { "uniprot_canonical_ac": "M0QW45-1", "uniprot_ac": "M0QW45", "uniprot_id": "M0QW45_BOVIN", "mass": { "chemical_mass": 34977.0, "monoisotopic_mass": 34977.0 }, "refseq": { "ac": "NP_001377679", "name": "olfactory receptor family 5 subfamily W member 39", "summary": "Olfactory receptors interact with odorant molecules in the nose, to initiate a neuronal response that triggers the perception of a smell. The olfactory receptor proteins are members of a large family of G-protein-coupled receptors (GPCR) arising from single coding-exon genes. Olfactory receptors share a 7-transmembrane domain structure with many neurotransmitter and hormone receptors and are responsible for the recognition and G protein-mediated transduction of odorant signals. The olfactory receptor gene family is the largest in the genome. 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The olfactory receptor proteins are members of a large family of G-protein-coupled receptors (GPCR) arising from single coding-exon genes. Olfactory receptors share a 7-transmembrane domain structure with many neurotransmitter and hormone receptors and are responsible for the recognition and G protein-mediated transduction of odorant signals. The olfactory receptor gene family is the largest in the genome. 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"evidence": [ { "id": "Q0II48", "url": "https://omabrowser.org/oma/group/Q0II48/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "A0A8V1AGI7-1", "protein_name": "BCL2 like 15", "gene_name": "BCL2L15", "tax_id": 9031, "organism": "Gallus gallus", "sequence": { "sequence": "MRTFEEQTVCVVEALFDDLLNEDEADFRCLQTDSGVSVQSEEEPPSGFDPVIIANRLRQIGDQCNMDFERVSSQVLREVLMGKMEKFGAAVDSLCRRWSDQNPELVYERAFLSVSVKLMMYILKKGAANVNPGHLVKAINENTQVKNYIEARGGWEKLDN", "length": 160 }, "evidence": [ { "id": "Q0II48", "url": "https://omabrowser.org/oma/group/Q0II48/", "database": "OMA" } ], "glygen_name": "Chicken", "common_name": "Chicken" }, { "uniprot_canonical_ac": "D4A1Q8-1", "protein_name": "Bcl-2-like protein 15", "gene_name": "Bcl2l15", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": 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sapiens", "sequence": { "sequence": "MKSSQTFEEQTECIVNTLLMDFLSPTLQVASRNLCCVDEVDSGEPCSFDVAIIAGRLRMLGDQFNGELEASAKNVIAETIKGQTGAILQDTVESLSKTWCAQDSSLAYERAFLAVSVKLLEYMAHIAPEVVGQVAIPMTGMINGNQAIREFIQGQGGWENLES", "length": 163 }, "evidence": [ { "id": "Q0II48", "url": "https://omabrowser.org/oma/group/Q0II48/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" } ], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 2, "go_terms": [ { "name": "nucleus", "id": "GO:0005634", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005634", "evidence": [ { "database": "UniProtKB", "id": "Q0II48", "url": "https://www.uniprot.org/uniprotkb/Q0II48" } ], "pmid": "" }, { "name": "cytosol", "id": "GO:0005829", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005829", "evidence": [ { "database": "UniProtKB", "id": "Q0II48", "url": "https://www.uniprot.org/uniprotkb/Q0II48" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 2, "go_terms": [ { "name": "apoptotic process", "id": "GO:0006915", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006915", "evidence": [ { "database": "UniProtKB", "id": "Q0II48", "url": "https://www.uniprot.org/uniprotkb/Q0II48" } ], "pmid": "" }, { "name": "regulation of apoptotic process", "id": "GO:0042981", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0042981", "evidence": [ { "database": "UniProtKB", "id": "Q0II48", "url": "https://www.uniprot.org/uniprotkb/Q0II48" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 30, "end_pos": 32, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [ { "pdb_id": "AF-Q0II48-F1", "pdb_chain": "global", "start_pos": 1, "end_pos": 162, "overlap": "1.0", "method": "AlphaFold", "type": "alphafold", "resolution": -1.0, "url": "https://data.glygen.org/ln2downloads/pdb/current/AF-Q0II48-F1.pdb", "url_external": 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}, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ], "tool_support": { "graph_view": "yes" } }, { "uniprot_canonical_ac": "Q0II65-1", "uniprot_ac": "Q0II65", "uniprot_id": "CCD70_BOVIN", "mass": { "chemical_mass": 27524.0, "monoisotopic_mass": 27524.0 }, "refseq": { "ac": "NP_001069191", "name": "coiled-coil domain-containing protein 70", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001069191" }, "gene_names": [ { "name": "CCDC70", "type": "recommended", "evidence": [ { "id": "Q0II65", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q0II65" } ] }, { "name": "CCDC70", "type": "synonym", "evidence": [ { "id": "NP_001069191", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001069191" } ] } ], "protein_names": [ { "name": "Coiled-coil domain-containing protein 70", "type": "recommended", "evidence": [ { "id": "Q0II65", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q0II65/entry#names_and_taxonomy" } ] }, { "name": "coiled-coil domain-containing protein 70", "type": "synonym", "evidence": [ { "id": "NP_001069191", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001069191" } ] } ], "function": [], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Bos taurus", "taxid": 9913, "evidence": [ { "database": "UniProtKB", "id": "Q0II65", "url": "https://www.uniprot.org/uniprotkb/Q0II65" } ], "common_name": "Bovine", "glygen_name": "Bovine", "reference_species": "Bos taurus [9913]" } ], "gene": [ { "name": "CCDC70", "url": "https://www.uniprot.org/uniprotkb/Q0II65", "locus": { "chromosome": "12", "start_pos": 21309643, "end_pos": 21239738, "strand": "-", "evidence": [ { "database": "Ensembl Gene", "id": "ENSBTAG00000019863", "url": "https://www.ensembl.org/id/ENSBTAG00000019863" } ] } } ], "crossref": [ { "id": "Q0II65", "url": "https://alphafold.ebi.ac.uk/entry/Q0II65", "database": "AlphaFoldDB", "categories": [] }, { "id": "ENSBTAG00000019863", "url": "https://bgee.org/?page=gene&gene_id=ENSBTAG00000019863", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "515635", "url": "https://www.ncbi.nlm.nih.gov/gene/515635", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "bta:515635", "url": "https://www.genome.jp/dbget-bin/www_bget?bta:515635", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "FREEMWN", "url": "https://omabrowser.org/oma/group/FREEMWN/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "Q0II65", "url": "https://www.orthodb.org/?gene=Q0II65", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "NP_001069191", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001069191", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "Q0II65", "url": "https://www.uniprot.org/uniprotkb/Q0II65", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "Q0II65-1", "url": "https://www.uniprot.org/uniprotkb/Q0II65-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MFPFKVRKWMGLACFRSLVVSSSSIRQKKLIHKLQEEKAFREEMRHFREKIEDFREEMWNFRSKMRAFRGEILGFWEEDRLFWEEEKTFWKEEKAFWEMEKSFREEEKAFWKKYRIFWKEDRAFWKEDNALWERDRNLLQEDKALWEEEKALWVEERALLEEEKVLWEDKKTLWEEENALWEEEKAAWVEGVVPVVEQQVLEGGHHHVSGRPRSPASSRGRA", "length": 222, "header": "sp|Q0II65-1|CCD70_BOVIN Isoform 1 of Coiled-coil domain-containing protein 70 OS=Bos taurus OX=9913 GN=CCDC70 PE=2 SV=1 CANONICAL=Q0II65-1" }, 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"id": "bta:515635", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?bta:515635", "resource": "KEGG Pathway" } ], "orthologs": [ { "uniprot_canonical_ac": "A0A4X1SQ39-1", "protein_name": "Coiled-coil domain containing 70", "gene_name": "CCDC70", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MFPFKVSKWMGLACFRSLAASSSSLRRKKLIHKLQEEKAFREEMKHFREKIEDFREEMWTFRGKICTFRGQILGFWEEERTFWEEEKTFWKEERAFWEMEKSFREEEKAFWKKYRIFWKEDKAFWKEDNALWERDRNLLQEDKALWEEERALWVEERALLEEEKALWEDKKSLWEEENALWQEEKAFWVEGGGQVAEEQMLEGGHHGGRRSPAFPRRRA", "length": 219 }, "evidence": [ { "id": "Q0II65", "url": "https://omabrowser.org/oma/group/Q0II65/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "B5DFG0-1", "protein_name": "Coiled-coil domain containing 70", "gene_name": "Ccdc70", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MFPFKVSKWMGLACLRSLVLPSPSIRQKKLIHKLQEEKAFREEMKIFHEKIEDFREEIWEFRGKIRAFRGQILGFWEEERPFWEEEKIFWKEEKTFWEMEKSFREEEKTFWKKYRTFWKEDKAFWREDNALWERDRNLLQEDKALWEEEKALWVEERALLAEEKALWEDKKSLWEEENALWEEEKALWVEGGGFHLLGEQRPQNGPYNVNEESQSTPFPRGRA", "length": 223 }, "evidence": [ { "id": "Q0II65", "url": "https://omabrowser.org/oma/group/Q0II65/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "Q6NSX1-1", "protein_name": "Coiled-coil domain-containing protein 70", "gene_name": "CCDC70", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MFSFKVSRWMGLACFRSLAASSPSIRQKKLMHKLQEEKAFREEMKIFREKIEDFREEMWTFRGKIHAFRGQILGFWEEERPFWEEEKTFWKEEKSFWEMEKSFREEEKTFWKKYRTFWKEDKAFWKEDNALWERDRNLLQEDKALWEEEKALWVEERALLEGEKALWEDKTSLWEEENALWEEERAFWMENNGHIAGEQMLEDGPHNANRGQRLLAFSRGRA", "length": 222 }, "evidence": [ { "id": "Q0II65", "url": "https://omabrowser.org/oma/group/Q0II65/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "Q9D9B0-1", "protein_name": "Coiled-coil domain-containing protein 70", "gene_name": "Ccdc70", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MFPFKVSKWMGLACLRSLVLPSPSIRQKKLIHKLQEEKAFREEMKIFHEKIEDFREEIWEFRGKIRAFRGQILGFWEEERPFWEEEKIFWKEEKTFWEMEKSFREEEKTFWKKYRTFWKEDKAFWREDNALWERDRNLLQEDKALWEEEKALWVEERALLAEEKALWEDKKSLWEEENALWEEEKALWVEGGGFHLLGEQRHQNGPYNANEEPQSTSFPRGRA", "length": 223 }, "evidence": [ { "id": "Q0II65", "url": "https://omabrowser.org/oma/group/Q0II65/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" } ], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 1, "go_terms": [ { "name": "plasma membrane", "id": "GO:0005886", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005886", "evidence": [ { "database": "UniProtKB", "id": "Q0II65", "url": "https://www.uniprot.org/uniprotkb/Q0II65" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [], "ptm_annotation": [], 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"NP_001071344", "name": "olfactory receptor 10H1", "summary": "Olfactory receptors interact with odorant molecules in the nose, to initiate a neuronal response that triggers the perception of a smell. The olfactory receptor proteins are members of a large family of G-protein-coupled receptors (GPCR) arising from single coding-exon genes. Olfactory receptors share a 7-transmembrane domain structure with many neurotransmitter and hormone receptors and are responsible for the recognition and G protein-mediated transduction of odorant signals. The olfactory receptor gene family is the largest in the genome. 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The olfactory receptor proteins are members of a large family of G-protein-coupled receptors (GPCR) arising from single coding-exon genes. Olfactory receptors share a 7-transmembrane domain structure with many neurotransmitter and hormone receptors and are responsible for the recognition and G protein-mediated transduction of odorant signals. The olfactory receptor gene family is the largest in the genome. [provided by RefSeq, Jul 2008].", "evidence": [ { "database": "RefSeq", "id": "NP_001071344", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001071344" } ] }, { "annotation": "Putative odorant or sperm cell receptor.", "evidence": [ { "database": "UniProtKB", "id": "Q0MQ71", "url": "https://www.uniprot.org/uniprotkb/Q0MQ71#function" }, { "database": "UniProtKB", "id": "ARBA00003929", "url": "https://www.uniprot.org/uniprotkb/ARBA00003929#function" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Bos taurus", "taxid": 9913, "evidence": [ { "database": "UniProtKB", "id": "Q0MQ71", "url": "https://www.uniprot.org/uniprotkb/Q0MQ71" } ], "common_name": "Bovine", "glygen_name": "Bovine", "reference_species": "Bos taurus [9913]" } ], "gene": [ { "name": "OR10H1", "url": "https://www.uniprot.org/uniprotkb/Q0MQ71", "locus": { "chromosome": "7", "start_pos": 7246650, "end_pos": 7247597, "strand": "+", "evidence": [ { "database": "Ensembl Gene", "id": "ENSBTAG00000001084", "url": "https://www.ensembl.org/id/ENSBTAG00000001084" } ] } } ], "crossref": [ { "id": "ENSBTAG00000001084", "url": "https://bgee.org/?page=gene&gene_id=ENSBTAG00000001084", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "cd15225", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd15225", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "508140", "url": "https://www.ncbi.nlm.nih.gov/gene/508140", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR000276", "url": "https://www.ebi.ac.uk/interpro/entry/IPR000276", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR000725", "url": "https://www.ebi.ac.uk/interpro/entry/IPR000725", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR017452", "url": "https://www.ebi.ac.uk/interpro/entry/IPR017452", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "bta:508140", "url": "https://www.genome.jp/dbget-bin/www_bget?bta:508140", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "MPGENCT", "url": "https://omabrowser.org/oma/group/MPGENCT/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "Q0MQ71", "url": "https://www.orthodb.org/?gene=Q0MQ71", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR26453", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR26453", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF13853", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF13853", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "R-BTA-381753", "url": "https://www.reactome.org/PathwayBrowser/#R-BTA-381753", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "NP_001071344", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001071344", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "Q0MQ71", "url": "https://www.uniprot.org/uniprotkb/Q0MQ71", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "Q0MQ71-1", "url": "https://www.uniprot.org/uniprotkb/Q0MQ71-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MQGANFSAVTEFILIGFSTFPHLQLMFFLLFLLMYLFTLLGNLLIMATIWREHSLHTPMYLFLCALSISEILYTFAIIPRMLADLLSTDRSISFTACASQMFFSFMFGFTHSFLLTVMGYDRYVAICHPLRYNVLMSPRGCACLVAWSWAGGSVMGLVVTSAIFHLIFCGPNEVHHFACHVPPLLKLACGTEVQVVAKGVGLVCITALLGCGLLILLSYAFIVAAILRIPSAEGRHKAFSTCASHLTVVVVHYGFASVIYLKPKGPQSLEGDTLMGITYTVLTPFLSPIIFSLRNKELKIAMKKTFLSKLYPEKI", "length": 315, "header": "tr|Q0MQ71-1|Q0MQ71_BOVIN Isoform 1 of Olfactory receptor family 10 subfamily H member 1 OS=Bos taurus OX=9913 GN=OR10H1 PE=3 SV=1 CANONICAL=Q0MQ71-1" }, "isoforms": [ { "isoform_ac": "Q0MQ71-1", "url": "https://www.uniprot.org/uniprotkb/Q0MQ71/entry", "sequence": { "sequence": "MQGANFSAVTEFILIGFSTFPHLQLMFFLLFLLMYLFTLLGNLLIMATIWREHSLHTPMYLFLCALSISEILYTFAIIPRMLADLLSTDRSISFTACASQMFFSFMFGFTHSFLLTVMGYDRYVAICHPLRYNVLMSPRGCACLVAWSWAGGSVMGLVVTSAIFHLIFCGPNEVHHFACHVPPLLKLACGTEVQVVAKGVGLVCITALLGCGLLILLSYAFIVAAILRIPSAEGRHKAFSTCASHLTVVVVHYGFASVIYLKPKGPQSLEGDTLMGITYTVLTPFLSPIIFSLRNKELKIAMKKTFLSKLYPEKI", "length": 315, "header": "tr|Q0MQ71-1|Q0MQ71_BOVIN Isoform 1 of Olfactory receptor family 10 subfamily H member 1 OS=Bos taurus OX=9913 GN=OR10H1 PE=3 SV=1 CANONICAL=Q0MQ71-1" }, "locus": { "chromosome": "7", "start_pos": 7247597, "end_pos": 7246653, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000001437.5", "url": "https://www.ensembl.org/id/ENSBTAT00000001437.5" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000001437.4", "url": "https://www.ensembl.org/id/ENSBTAP00000001437.4" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [ { "id": "bta:508140", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?bta:508140", "resource": "KEGG Pathway" }, { "id": "R-BTA-381753", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-BTA-381753", "resource": "Reactome", "description": "Olfactory Signaling Pathway" } ], "orthologs": [ { "uniprot_canonical_ac": "A0A3L7HL20-1", "protein_name": "Olfactory receptor 10H1", "gene_name": "LOC100773239", "tax_id": 10029, "organism": "Cricetulus griseus", "sequence": { "sequence": "MQGINHSGVSEFILIGFSTFPHLQMVFFLLFLLMYLFTLLGNLFIMATIWSERSLHTPMYLFLCALSISEIFYTFAIIPRMLADLLSTLHSIAFLACASQMFFSFTFGFTHSFLLTVMGYDRYVAICHPLRYNVLMSPRGCTCLVAWSWVGGSFMGTVVTTAIFNLTFCGPNEIHHFACHVPPLLKLACGENVLVVARGVGLVCITALLGCFLLILLSYAFIVAAILKIPSAEGRHKAFSTCASHLTVVIVHYGFASVIYLKPKGPKSLEGDTLMGITYTVLTPFLSPIIFSLRNKELKNAMKKAFLSKLYPEII", "length": 315 }, "evidence": [ { "id": "Q0MQ71", "url": "https://omabrowser.org/oma/group/Q0MQ71/", "database": "OMA" } ], "glygen_name": "Hamster", "common_name": "Chinese hamster" }, { "uniprot_canonical_ac": "F1SA00-1", "protein_name": "G-protein coupled receptors family 1 profile domain-containing protein", "gene_name": "LOC100524975", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MQGANLSAVTEFILIGFSTFPHLQLTFFLLFLLMYLFTLLGNLLIMATIWRERSLHTPMYLFLCALSISEILYTFAIIPRMLADLLSTHHSIAFSACASQMFFSFTFGFTHSFLLTVMGYDRYVAICHPLRYNVLMSPGGCACLVVWSWAGGLVMGLVVTSAIFHLTFCGPNEIHHFACHVPPLLKLACGTDVHVVAKGVGLVCLSALLGCCLLILLSYAFIVAAILRIPSAEGRHKAFSTCVSHLTVVVVHYGFASVIYLKPKGPPSLEGDTLMGITYTVLTPFLSPIIFSLRNKELKNTMNKTFSKLYPETM", "length": 314 }, "evidence": [ { "id": "Q0MQ71", "url": "https://omabrowser.org/oma/group/Q0MQ71/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "Q9Y4A9-1", "protein_name": "Olfactory receptor 10H1", "gene_name": "OR10H1", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MQRANHSTVTQFILVGFSVFPHLQLMLFLLFLLMYLFTLLGNLLIMATVWSERSLHTPMYLFLCALSVSEILYTVAIIPRMLADLLSTQRSIAFLACASQMFFSFSFGFTHSFLLTVMGYDRYVAICHPLRYNVLMSPRGCACLVGCSWAGGLVMGMVVTSAIFHLAFCGHKEIHHFACHVPPLLKLACGDDVLVVAKGVGLVCITALLGCFLLILLSYAFIVAAILKIPSAEGRNKAFSTCASHLTVVVVHYGFASVIYLKPKSPQSLEGDTLMGITYTVLTPFLSPIIFSLRNKELKVAMKKTFFSKLYPEKNVMM", "length": 318 }, "evidence": [ { "id": "Q0MQ71", "url": "https://omabrowser.org/oma/group/Q0MQ71/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" } ], "go_annotation": { "categories": [ { "name": "Molecular Function", "total": 2, "go_terms": [ { "name": "G protein-coupled receptor activity", "id": "GO:0004930", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0004930", "evidence": [ { "database": "UniProtKB", "id": "Q0MQ71", "url": "https://www.uniprot.org/uniprotkb/Q0MQ71" } ], "pmid": "" }, { "name": "olfactory receptor activity", "id": "GO:0004984", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0004984", "evidence": [ { "database": "UniProtKB", "id": "Q0MQ71", "url": "https://www.uniprot.org/uniprotkb/Q0MQ71" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 1, "go_terms": [ { "name": "plasma membrane", "id": "GO:0005886", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005886", "evidence": [ { "database": "UniProtKB", "id": "Q0MQ71", "url": "https://www.uniprot.org/uniprotkb/Q0MQ71" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 1, "go_terms": [ { "name": "detection of chemical stimulus involved in sensory perception of smell", "id": "GO:0050911", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0050911", "evidence": [ { "database": "UniProtKB", "id": "Q0MQ71", "url": "https://www.uniprot.org/uniprotkb/Q0MQ71" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 5, "end_pos": 7, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "Q0MQ71", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q0MQ71" }, { "id": "PS50262", "database": "PROSITE", "url": "https://prosite.expasy.org/PS50262" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "G-protein coupled receptors family 1 profile", "eco_id": "ECO_0000259", "start_pos": 41, "end_pos": 291, "start_aa": "Gly", "end_aa": "Phe", "glycosite_overlap": [] } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "homologset.oma", "label": "OMA Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 5, "end_pos": 7 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ], "tool_support": { "graph_view": "yes" } }, { "uniprot_canonical_ac": "Q0V7M8-1", "uniprot_ac": "Q0V7M8", "uniprot_id": "F167A_BOVIN", "mass": { "chemical_mass": 24055.0, "monoisotopic_mass": 24055.0 }, "refseq": { "ac": "NP_001069962", "name": "protein FAM167A", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001069962" }, "gene_names": [ { "name": "FAM167A", "type": "recommended", "evidence": [ { "id": "Q0V7M8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q0V7M8" } ] }, { "name": "C8H8orf13", "type": "synonym", "evidence": [ { "id": "NP_001069962", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001069962" } ] }, { "name": "C8orf13", "type": "synonym", "evidence": [ { "id": "NP_001069962", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001069962" } ] }, { "name": "FAM167A", "type": "synonym", "evidence": [ { "id": "NP_001069962", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001069962" } ] } ], "protein_names": [ { "name": "Protein FAM167A", "type": "recommended", "evidence": [ { "id": "Q0V7M8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q0V7M8/entry#names_and_taxonomy" } ] }, { "name": "protein FAM167A", "type": "synonym", "evidence": [ { "id": "NP_001069962", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001069962" } ] } ], "function": [], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Bos taurus", "taxid": 9913, "evidence": [ { "database": "UniProtKB", "id": "Q0V7M8", "url": "https://www.uniprot.org/uniprotkb/Q0V7M8" } ], "common_name": "Bovine", "glygen_name": "Bovine", "reference_species": "Bos taurus [9913]" } ], "gene": [ { "name": "FAM167A", "url": "https://www.uniprot.org/uniprotkb/Q0V7M8", "locus": { "chromosome": "8", "start_pos": 7929036, "end_pos": 7897571, "strand": "-", "evidence": [ { "database": "Ensembl Gene", "id": "ENSBTAG00000019066", "url": "https://www.ensembl.org/id/ENSBTAG00000019066" } ] } } ], "crossref": [ { "id": "Q0V7M8", "url": "https://alphafold.ebi.ac.uk/entry/Q0V7M8", "database": "AlphaFoldDB", "categories": [] }, { "id": "ENSBTAG00000019066", "url": "https://bgee.org/?page=gene&gene_id=ENSBTAG00000019066", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "618107", "url": "https://www.ncbi.nlm.nih.gov/gene/618107", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR024280", "url": "https://www.ebi.ac.uk/interpro/entry/IPR024280", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR051771", "url": "https://www.ebi.ac.uk/interpro/entry/IPR051771", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "bta:618107", "url": "https://www.genome.jp/dbget-bin/www_bget?bta:618107", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "PQIHIEE", "url": "https://omabrowser.org/oma/group/PQIHIEE/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "Q0V7M8", "url": "https://www.orthodb.org/?gene=Q0V7M8", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR32289", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR32289", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR32289:SF3", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR32289:SF3", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF11652", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF11652", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "NP_001069962", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001069962", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0AAF7AL66", "url": "https://www.uniprot.org/uniprotkb/A0AAF7AL66", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0AAF7AL66-1", "url": "https://www.uniprot.org/uniprotkb/A0AAF7AL66-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "Q0V7M8", "url": "https://www.uniprot.org/uniprotkb/Q0V7M8", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "Q0V7M8-1", "url": "https://www.uniprot.org/uniprotkb/Q0V7M8-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MSVPQIQVEEVAGGEEGPAGTTPPPDDHLRSLKALTEKLRLETRRPSYLEWQARLEEQTWPFPRPAAEPRGSGEEEPSLLRTRALRPHPPPNGRANQDDGHPPTGKLEGFESIDEAIAWLRKELMEMRLQDQQLARQLMRLRSDIHKLKIEQTCDLHRRMLNDATYELEERDELSDLFCDAPLASSFSLSAPLKLIGVTKMNINSRRFSLC", "length": 211, "header": "sp|Q0V7M8-1|F167A_BOVIN Isoform 1 of Protein FAM167A OS=Bos taurus OX=9913 GN=FAM167A PE=2 SV=1 CANONICAL=Q0V7M8-1" }, "isoforms": [ { "isoform_ac": "A0AAF7AL66-1", "url": "https://www.uniprot.org/uniprotkb/A0AAF7AL66/entry", "sequence": { "sequence": "MSVPQIQVEEVAGGEEGPAGTTPPPDDHLRSLKALTEKLRLETRRPSYLEWQARLEEQTWPFPRPAAEPRGSGEEEPSLLRTRALRPHPPPNGRANQDDGHPPTGKLEGFESIDEAIAWLRKELRNRDQSTLSASCEDTVRRWKNLSARKCPHWELTQHTKSLNLDFPACRTMEMRLQDQQLARQLMRLRSDIHKLKIEQTCDLHRRMLNDATYELEERDELSDLFCDAPLASSFSLSAPLKLIGVTKMNINSRRFSLC", "length": 259, "header": "tr|A0AAF7AL66-1|A0AAF7AL66_BOVIN Computationally mapped isoform of Family with sequence similarity 167 member A OS=Bos taurus OX=9913 GN=FAM167A PE=3 SV=1 CANONICAL=Q0V7M8-1" }, "locus": { "chromosome": "8", "start_pos": 7926289, "end_pos": 7912017, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000079846.2", "url": "https://www.ensembl.org/id/ENSBTAT00000079846.2" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000071188.2", "url": "https://www.ensembl.org/id/ENSBTAP00000071188.2" } ] } }, { "isoform_ac": "Q0V7M8-1", "url": "https://www.uniprot.org/uniprotkb/Q0V7M8/entry#Q0V7M8-1", "sequence": { "sequence": "MSVPQIQVEEVAGGEEGPAGTTPPPDDHLRSLKALTEKLRLETRRPSYLEWQARLEEQTWPFPRPAAEPRGSGEEEPSLLRTRALRPHPPPNGRANQDDGHPPTGKLEGFESIDEAIAWLRKELMEMRLQDQQLARQLMRLRSDIHKLKIEQTCDLHRRMLNDATYELEERDELSDLFCDAPLASSFSLSAPLKLIGVTKMNINSRRFSLC", "length": 211, "header": "sp|Q0V7M8-1|F167A_BOVIN Isoform 1 of Protein FAM167A OS=Bos taurus OX=9913 GN=FAM167A PE=2 SV=1 CANONICAL=Q0V7M8-1" }, "locus": { "chromosome": "8", "start_pos": 7926289, "end_pos": 7912017, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000025383.4", "url": "https://www.ensembl.org/id/ENSBTAT00000025383.4" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000025383.3", "url": "https://www.ensembl.org/id/ENSBTAP00000025383.3" } ] } } ], "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "other", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 22, "start_aa": "Thr", "end_pos": 22, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr22", "evidence": [ { "id": "", "database": "GlyGen", "url": "https://data.glygen.org/" } ], "filter_code": "000000000000000010000.00000000001000.0.01000" } ], "phosphorylation": [], "glycation": [], "keywords": [ "glycoprotein", "glycoprotein_predicted" ], "publication": [ { "title": "Characterization of 954 bovine full-CDS cDNA sequences.", "journal": "BMC Genomics", "date": "2005", "authors": "Harhay Gregory P, Sonstegard Tad S, Keele John W, Heaton Michael P, Clawson Michael L, Snelling Warren M, Wiedmann Ralph T, Van Tassell Curt P, Smith Timothy P L", "evidence": [ { "database": "UniProtKB", "id": "Q0V7M8", "url": "https://www.uniprot.org/uniprotkb/Q0V7M8" } ], "reference": [ { "type": "PubMed", "id": "16305752", "url": "https://glygen.org/publication/PubMed/16305752" } ] } ], "pathway": [ { "id": "bta:618107", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?bta:618107", "resource": "KEGG Pathway" } ], "orthologs": [ { "uniprot_canonical_ac": "A0A287B6D5-1", "protein_name": "Family with sequence similarity 167 member A", "gene_name": "FAM167A", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MSVPQVQVEEAVCGEEGPAEAAPPPDDHLRSLKALTEKLRLETRRPSYLEWQARLEEQTWPFPRPAAGQRGCAEKEAVLPPRAPGQHPPPNRRASQDDEPQATGRLEGFESIDEALAWLRKELTEMRLQDQQLARQLMRLRSDIHKLKIEQTCDLHRRMLNDATYELEERDELSDLFCDAPLASSFSLSAPLKLIGVTKMNINSRRFSLC", "length": 210 }, "evidence": [ { "id": "Q0V7M8", "url": "https://omabrowser.org/oma/group/Q0V7M8/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "A0A8C2MR57-1", "protein_name": "Protein FAM167A", "gene_name": "Fam167a", "tax_id": 10029, "organism": "Cricetulus griseus", "sequence": { "sequence": "MSVPRIQVDEVGENDRPAGAAAPPDDHLLSLKALTEKLRLETRRPSYLEWQARLEEQTWPFPRSAAQQEASLEEGACGGGEPSIPLRESRELLPPARSASQGDGPLTTGKLEGFQSIDEAITWLRKELAEMRLQDQQLARQLMRLRGDINKLKIEQTCRLHRRMLNDAAYELEERDELSDLFCDSPLASSFSLSTPLKLIGVTKMNINSRRFSLC", "length": 215 }, "evidence": [ { "id": "Q0V7M8", "url": "https://omabrowser.org/oma/group/Q0V7M8/", "database": "OMA" } ], "glygen_name": "Hamster", "common_name": "Chinese hamster" }, { "uniprot_canonical_ac": "A0A8V0YH59-1", "protein_name": "Family with sequence similarity 167 member A", "gene_name": "FAM167A", "tax_id": 9031, "organism": "Gallus gallus", "sequence": { "sequence": "MSLPKIQIEEALDRTDAGTGSAVPPDDHLRSLKALTEKLRLETRRPSYLEWKAKLEEQAWKSPQPVGDEEGNEAKKGAEDTVPLRKVQLHLNGSPAQDKVTLTSGKIGDFESIDEALTWLRKELVTHLSARFCHLHMKIWPWYIGLNMPTELQPALSAGTCWESGPEKLIYSDMQIPALVFVLRGSVNAPAGPAAGQAADAPPQRHQQAEDRADLPPPPAHAQRRHV", "length": 227 }, "evidence": [ { "id": "Q0V7M8", "url": "https://omabrowser.org/oma/group/Q0V7M8/", "database": "OMA" } ], "glygen_name": "Chicken", "common_name": 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"evidence": [ { "id": "Q0V7M8", "url": "https://omabrowser.org/oma/group/Q0V7M8/", "database": "OMA" } ], "glygen_name": "Zebrafish", "common_name": "Zebrafish" }, { "uniprot_canonical_ac": "Q6P1G6-1", "protein_name": "Protein FAM167A", "gene_name": "Fam167a", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MSVPQIQVEEVSEKDRPAGAAVPPDDHLLSLKALTEKLRLETRRPSYLEWQARLEEQTWPFPRPAAQQEASLEQGACGGGEPLMPLKEPRDLLPPSASAGRGDRPLTTGKLEGFQSIDEAIAWLRKELAEMRLQDQQLARQLMRLRGDINKLKIEQTCRLHRRMLNDAAFELEERDELSDLFCDSPLASSFSLSMPLKLIGVTKMNINSRRFSLC", "length": 215 }, "evidence": [ { "id": "Q0V7M8", "url": "https://omabrowser.org/oma/group/Q0V7M8/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q96KS9-1", "protein_name": "Protein FAM167A", "gene_name": "FAM167A", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MSVPQIHVEEVGAEEGAGAAAPPDDHLRSLKALTEKLRLETRRPSYLEWQARLEEHTWPFPRPAAEPQASLEEGERGGQEPLLPLREAGQHPPSARSASQGARPLSTGKLEGFQSIDEAIAWLRKELTEMRLQDQQLARQLMRLRGDINKLKIEHTCRLHRRMLNDATYELEERDELADLFCDSPLASSFSLSTPLKLIGVTKMNINSRRFSLC", "length": 214 }, "evidence": [ { "id": "Q0V7M8", "url": "https://omabrowser.org/oma/group/Q0V7M8/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" } ], "go_annotation": {}, "pro_annotation": [], "site_annotation": [], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [ { "pdb_id": "AF-Q0V7M8-F1", "pdb_chain": "global", "start_pos": 1, "end_pos": 211, "overlap": "1.0", "method": "AlphaFold", "type": "alphafold", "resolution": -1.0, "url": "https://data.glygen.org/ln2downloads/pdb/current/AF-Q0V7M8-F1.pdb", "url_external": "https://alphafold.ebi.ac.uk/entry/Q0V7M8" } ], "lectin_list": [], "domain_list": [], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" }, { "name": "homologset.oma", "label": "OMA Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [ 22 ], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 1 }, { "field": "total_sites", "count": 1 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 1 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "exact_sites", "count": 1 }, { "field": "exact_o_linked_sites", "count": 1 }, { "field": "fuzzy_sites", "count": 0 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", 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"uniprot_canonical_ac": "Q0VC09-1", "uniprot_ac": "Q0VC09", "uniprot_id": "RIBC1_BOVIN", "mass": { "chemical_mass": 44248.0, "monoisotopic_mass": 44248.0 }, "refseq": { "ac": "NP_001069053", "name": "RIB43A-like with coiled-coils protein 1", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001069053" }, "gene_names": [ { "name": "RIBC1", "type": "recommended", "evidence": [ { "id": "Q0VC09", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q0VC09" } ] }, { "name": "RIBC1", "type": "synonym", "evidence": [ { "id": "NP_001069053", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001069053" } ] } ], "protein_names": [ { "name": "RIB43A-like with coiled-coils protein 1", "type": "recommended", "evidence": [ { "id": "Q0VC09", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q0VC09/entry#names_and_taxonomy" } ] }, { "name": "RIB43A-like with coiled-coils protein 1", "type": "synonym", "evidence": [ { "id": "NP_001069053", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001069053" } ] } ], "function": [], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Bos taurus", "taxid": 9913, "evidence": [ { "database": "UniProtKB", "id": "Q0VC09", "url": "https://www.uniprot.org/uniprotkb/Q0VC09" } ], "common_name": "Bovine", "glygen_name": "Bovine", "reference_species": "Bos taurus [9913]" } ], "gene": [ { "name": "RIBC1", "url": "https://www.uniprot.org/uniprotkb/Q0VC09", "locus": { "chromosome": "X", "start_pos": 90870919, "end_pos": 90856243, "strand": "-", "evidence": [ { "database": "Ensembl Gene", "id": "ENSBTAG00000017769", "url": "https://www.ensembl.org/id/ENSBTAG00000017769" } ] } } ], "crossref": [ { "id": "Q0VC09", "url": "https://alphafold.ebi.ac.uk/entry/Q0VC09", "database": "AlphaFoldDB", "categories": [] }, { "id": "512894", "url": "https://www.ncbi.nlm.nih.gov/gene/512894", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR008805", "url": "https://www.ebi.ac.uk/interpro/entry/IPR008805", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "bta:512894", "url": "https://www.genome.jp/dbget-bin/www_bget?bta:512894", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "Q0VC09", "url": "https://www.orthodb.org/?gene=Q0VC09", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR14517", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR14517", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR14517:SF11", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR14517:SF11", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF05914", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF05914", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "NP_001069053", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001069053", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "Q0VC09", "url": "https://www.uniprot.org/uniprotkb/Q0VC09", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "Q0VC09-1", "url": "https://www.uniprot.org/uniprotkb/Q0VC09-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MYQVDLPPDPKEVAAIEARRNQEREQQSRFFNVRTRVMGVDVEALNNQVEERKLQEATERSKEAAYGTNQVRYDLVAQMLEKEQAERTRRLAKKVQNFREQRQKLRNRCELDFWNSNQLWREFPAYLGDNAPYYGQASLQCFSGEDLERATYLRMQQEQFQYSLERQLQEQQQARVDENCADMLNDQLRLAMDMRAAQLAKLEESCRIAMMAATASANKAQAVKLAEQQGQEHQRQQEANLVEVQNQITSDLLTENPQVAQNPVAPHRVLPYCWKGMTPEQRATIRKVQETQHHEKEAQRQAEQALDAKWESQAINLAQAAKELEEQERELCAEFRRGLGSFNQQLAMEQNAQQNYLNSIIYTNQPTAQYHLQFNTSSR", "length": 379, "header": "sp|Q0VC09-1|RIBC1_BOVIN Isoform 1 of RIB43A-like with coiled-coils protein 1 OS=Bos taurus OX=9913 GN=RIBC1 PE=2 SV=1 CANONICAL=Q0VC09-1" }, "isoforms": [ { "isoform_ac": "Q0VC09-1", "url": "https://www.uniprot.org/uniprotkb/Q0VC09/entry#Q0VC09-1", "sequence": { "sequence": "MYQVDLPPDPKEVAAIEARRNQEREQQSRFFNVRTRVMGVDVEALNNQVEERKLQEATERSKEAAYGTNQVRYDLVAQMLEKEQAERTRRLAKKVQNFREQRQKLRNRCELDFWNSNQLWREFPAYLGDNAPYYGQASLQCFSGEDLERATYLRMQQEQFQYSLERQLQEQQQARVDENCADMLNDQLRLAMDMRAAQLAKLEESCRIAMMAATASANKAQAVKLAEQQGQEHQRQQEANLVEVQNQITSDLLTENPQVAQNPVAPHRVLPYCWKGMTPEQRATIRKVQETQHHEKEAQRQAEQALDAKWESQAINLAQAAKELEEQERELCAEFRRGLGSFNQQLAMEQNAQQNYLNSIIYTNQPTAQYHLQFNTSSR", "length": 379, "header": "sp|Q0VC09-1|RIBC1_BOVIN Isoform 1 of RIB43A-like with coiled-coils protein 1 OS=Bos taurus OX=9913 GN=RIBC1 PE=2 SV=1 CANONICAL=Q0VC09-1" }, "locus": {} } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [ { "id": "bta:512894", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?bta:512894", "resource": "KEGG Pathway" } ], "orthologs": [], "go_annotation": { "categories": [ { "name": "Biological Process", "total": 1, "go_terms": [ { "name": "flagellated sperm motility", "id": "GO:0030317", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030317", "evidence": [ { "database": "UniProtKB", "id": "Q0VC09", "url": "https://www.uniprot.org/uniprotkb/Q0VC09" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 2, "go_terms": [ { "name": "sperm flagellum", "id": "GO:0036126", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0036126", "evidence": [ { "database": "UniProtKB", "id": "Q0VC09", "url": "https://www.uniprot.org/uniprotkb/Q0VC09" } ], "pmid": "" }, { "name": "axonemal A tubule inner sheath", "id": "GO:0160111", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0160111", "evidence": [ { "database": "UniProtKB", "id": "Q0VC09", "url": "https://www.uniprot.org/uniprotkb/Q0VC09" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 375, "end_pos": 377, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], 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"NP_001069561", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001069561" } ] }, { "name": "cysteine-rich DPF motif domain-containing protein 1", "type": "synonym", "evidence": [ { "id": "NP_001069561", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001069561" } ] } ], "function": [], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Bos taurus", "taxid": 9913, "evidence": [ { "database": "UniProtKB", "id": "Q0VCH3", "url": "https://www.uniprot.org/uniprotkb/Q0VCH3" } ], "common_name": "Bovine", "glygen_name": "Bovine", "reference_species": "Bos taurus [9913]" } ], "gene": [ { "name": "CDPF1", "url": "https://www.uniprot.org/uniprotkb/Q0VCH3", "locus": { "chromosome": "5", "start_pos": 116513933, "end_pos": 116523076, "strand": "+", "evidence": [ { "database": "Ensembl Gene", "id": "ENSBTAG00000008065", "url": "https://www.ensembl.org/id/ENSBTAG00000008065" } ] } } ], "crossref": [ { "id": "Q0VCH3", "url": "https://alphafold.ebi.ac.uk/entry/Q0VCH3", "database": "AlphaFoldDB", "categories": [] }, { "id": "ENSBTAG00000008065", "url": "https://bgee.org/?page=gene&gene_id=ENSBTAG00000008065", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "537366", "url": "https://www.ncbi.nlm.nih.gov/gene/537366", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR018785", "url": "https://www.ebi.ac.uk/interpro/entry/IPR018785", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR042426", "url": "https://www.ebi.ac.uk/interpro/entry/IPR042426", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "bta:537366", "url": "https://www.genome.jp/dbget-bin/www_bget?bta:537366", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "CDMHELV", "url": "https://omabrowser.org/oma/group/CDMHELV/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "Q0VCH3", "url": "https://www.orthodb.org/?gene=Q0VCH3", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR31849", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR31849", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR31849:SF1", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR31849:SF1", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF10170", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF10170", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "NP_001069561", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001069561", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "Q0VCH3", "url": "https://www.uniprot.org/uniprotkb/Q0VCH3", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "Q0VCH3-1", "url": "https://www.uniprot.org/uniprotkb/Q0VCH3-1", "database": "UniProtKB", 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"evidence": [ { "id": "Q0VCH3", "url": "https://omabrowser.org/oma/group/Q0VCH3/", "database": "OMA" } ], "glygen_name": "Fruit fly", "common_name": "Fruit fly" } ], "go_annotation": {}, "pro_annotation": [], "site_annotation": [], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [ { "pdb_id": "AF-Q0VCH3-F1", "pdb_chain": "global", "start_pos": 1, "end_pos": 121, "overlap": "1.0", "method": "AlphaFold", "type": "alphafold", "resolution": -1.0, "url": "https://data.glygen.org/ln2downloads/pdb/current/AF-Q0VCH3-F1.pdb", "url_external": "https://alphafold.ebi.ac.uk/entry/Q0VCH3" } ], "lectin_list": [], "domain_list": [], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "homologset.oma", "label": "OMA Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], 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"database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR026698", "url": "https://www.ebi.ac.uk/interpro/entry/IPR026698", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR032710", "url": "https://www.ebi.ac.uk/interpro/entry/IPR032710", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "bta:511707", "url": "https://www.genome.jp/dbget-bin/www_bget?bta:511707", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "Q0VCL9", "url": "https://www.orthodb.org/?gene=Q0VCL9", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR21084", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR21084", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR21084:SF1", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR21084:SF1", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": 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"MKPESGQALFHVALASCLCVATVHTGIFEHVSVQVGYEYYAEAPVTSLPAFLAMPFNSLVNMAYVFLGVYWLRSQARAPGGPAERRRARYLKDVFAGMALVYGPVQWLRIGMQTQPTAVLDQWLTLPIFAWPVAWCLCLDRGWKPWLFLAVEGLSLCSYSLALLHPHGFELALGLHIAAAVGQALRIQGRHGNISSGTYLALGVLSCLGFVVLKLCDHELAQWHLFQQLTGHFWSKVCDVLQFHFAFLFLTSLHTC", "length": 256, "header": "sp|Q0VCM2-1|TM187_BOVIN Isoform 1 of Transmembrane protein 187 OS=Bos taurus OX=9913 GN=TMEM187 PE=2 SV=1 CANONICAL=Q0VCM2-1" }, "isoforms": [ { "isoform_ac": "Q0VCM2-1", "url": "https://www.uniprot.org/uniprotkb/Q0VCM2/entry#Q0VCM2-1", "sequence": { "sequence": "MKPESGQALFHVALASCLCVATVHTGIFEHVSVQVGYEYYAEAPVTSLPAFLAMPFNSLVNMAYVFLGVYWLRSQARAPGGPAERRRARYLKDVFAGMALVYGPVQWLRIGMQTQPTAVLDQWLTLPIFAWPVAWCLCLDRGWKPWLFLAVEGLSLCSYSLALLHPHGFELALGLHIAAAVGQALRIQGRHGNISSGTYLALGVLSCLGFVVLKLCDHELAQWHLFQQLTGHFWSKVCDVLQFHFAFLFLTSLHTC", "length": 256, "header": "sp|Q0VCM2-1|TM187_BOVIN Isoform 1 of Transmembrane protein 187 OS=Bos taurus OX=9913 GN=TMEM187 PE=2 SV=1 CANONICAL=Q0VCM2-1" }, "locus": { "chromosome": "X", 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} ], "glygen_name": "Human", "common_name": "Human" } ], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 2, "go_terms": [ { "name": "membrane", "id": "GO:0016020", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016020", "evidence": [ { "database": "UniProtKB", "id": "Q0VCM2", "url": "https://www.uniprot.org/uniprotkb/Q0VCM2" } ], "pmid": "" }, { "name": "transport vesicle", "id": "GO:0030133", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030133", "evidence": [ { "database": "UniProtKB", "id": "Q0VCM2", "url": "https://www.uniprot.org/uniprotkb/Q0VCM2" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 193, "end_pos": 195, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [ { "pdb_id": "AF-Q0VCM2-F1", "pdb_chain": "global", "start_pos": 1, "end_pos": 256, "overlap": "1.0", "method": 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"categories": [ "Genome Annotation" ] }, { "id": "IPR026572", "url": "https://www.ebi.ac.uk/interpro/entry/IPR026572", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "bta:780867", "url": "https://www.genome.jp/dbget-bin/www_bget?bta:780867", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "FYICTAC", "url": "https://omabrowser.org/oma/group/FYICTAC/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "Q17QJ2", "url": "https://www.orthodb.org/?gene=Q17QJ2", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR13628", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR13628", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR13628:SF1", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR13628:SF1", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "NP_001073263", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001073263", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "Q17QJ2", "url": "https://www.uniprot.org/uniprotkb/Q17QJ2", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "Q17QJ2-1", "url": "https://www.uniprot.org/uniprotkb/Q17QJ2-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MASETEKTHALLQSCSTESLLSSLGLGLFCTVADRLLQFPIIQQNAWLRALSDNSVHCVIGMWSWAIVIGIRKKTDFGEIILAGFLASVIDIDHFLLSGSLSLKAALSLPRRPFLHCSTVIPTVVLTLKFTMHFFKLKDSWCFLPWMLFISWTSHHIRDGIRHGLWMCPFGKTSPLPFWLYVIITSSLPHICSFVMYFTGTRQMMSSKHGIHIDV", "length": 215, "header": "sp|Q17QJ2-1|TM267_BOVIN Isoform 1 of Transmembrane protein 267 OS=Bos taurus OX=9913 GN=TMEM267 PE=2 SV=1 CANONICAL=Q17QJ2-1" }, "isoforms": [ { "isoform_ac": "Q17QJ2-1", "url": "https://www.uniprot.org/uniprotkb/Q17QJ2/entry#Q17QJ2-1", "sequence": { "sequence": "MASETEKTHALLQSCSTESLLSSLGLGLFCTVADRLLQFPIIQQNAWLRALSDNSVHCVIGMWSWAIVIGIRKKTDFGEIILAGFLASVIDIDHFLLSGSLSLKAALSLPRRPFLHCSTVIPTVVLTLKFTMHFFKLKDSWCFLPWMLFISWTSHHIRDGIRHGLWMCPFGKTSPLPFWLYVIITSSLPHICSFVMYFTGTRQMMSSKHGIHIDV", "length": 215, "header": "sp|Q17QJ2-1|TM267_BOVIN Isoform 1 of Transmembrane protein 267 OS=Bos taurus OX=9913 GN=TMEM267 PE=2 SV=1 CANONICAL=Q17QJ2-1" }, "locus": { "chromosome": "20", "start_pos": 31351635, "end_pos": 31347751, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSBTAT00000047186.4", "url": "https://www.ensembl.org/id/ENSBTAT00000047186.4" }, { "database": "Ensembl Peptide", "id": "ENSBTAP00000044410.1", "url": "https://www.ensembl.org/id/ENSBTAP00000044410.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [ { "title": "Characterization of 954 bovine full-CDS cDNA sequences.", "journal": "BMC Genomics", "date": "2005", "authors": "Harhay Gregory P, Sonstegard Tad S, Keele John 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"https://omabrowser.org/oma/group/Q17QJ2/", "database": "OMA" } ], "glygen_name": "Chicken", "common_name": "Chicken" }, { "uniprot_canonical_ac": "A0A8I6AG39-1", "protein_name": "Transmembrane protein 267", "gene_name": "Tmem267", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MRTKQRNRQDIFHLCLRLWRRVELTAAISSSGEGPALLREDPASLRLRGLGGLGRSGQPALVSLWCGQGAEPCWLARGPRSALGKTELQQAGRTGTDGPWCVQREAGAGMQGMQTRIACWFLMSFTLVTQFMMASKVEKTHALPPCYSTESLISSLGLGIFCLIADRLLRFSIIQQSDWLRALSDNVVHGVIGMWSWAVVIGIRKKSDFAEVLLAGFLASVIDVDHFFMARSLSLQAALTLQRRPFLHCSTVIPITVLSVKLAMHLFKLRDSWRFLPWMIFISWTSHHIRDGIRHGLWICPFGKTPPLPFWFYVISTLSLPHTCSFLMYLTGTRETMSSKHEMRIDV", "length": 347 }, "evidence": [ { "id": "Q17QJ2", "url": "https://omabrowser.org/oma/group/Q17QJ2/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "I3L8R5-1", "protein_name": "Transmembrane protein 267", "gene_name": "TMEM267", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MASETEKTHALLQSCSTESLISSLGLGIFCLVADRLLQFSIIQQNDWLRALSDNSVHCVIGMWSWTIVIGIKKKTDFGEIILAGFLASIIDIDHFFLAGSLSLKAALTLPRRPFLHCSTVIPIVVLTVKFTMHLFKLKDSWCFLPWMLFISWTSHHVRDGIRHGLWICPFGKTSPLPFWLYVIITSSLPHICSFVMYFTGTRQVMSSKHGIHIDV", "length": 215 }, "evidence": [ { "id": "Q17QJ2", "url": "https://omabrowser.org/oma/group/Q17QJ2/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "Q0VDI3-1", "protein_name": "Transmembrane protein 267", "gene_name": "TMEM267", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MASETEKTHALLQTCSTESLISSLGLGAFCLVADRLLQFSTIQQNDWLRALSDNAVHCVIGMWSWAVVTGIKKKTDFGEIILAGFLASVIDVDHFFLAGSMSLKAALTLPRRPFLHCSTVIPVVVLTLKFTMHLFKLKDSWCFLPWMLFISWTSHHIRDGIRHGLWICPFGKTSPLPFWLYVIITSSLPHICSFVMYLTGTRQMMSSKHGVRIDV", "length": 215 }, "evidence": [ { "id": "Q17QJ2", "url": "https://omabrowser.org/oma/group/Q17QJ2/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": 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