{
    "glytoucan_ac": "G00672PE",
    "number_monosaccharides": 4,
    "mass": 900.25,
    "mass_pme": 1096.47,
    "fully_determined": "yes",
    "iupac": "alpha-D-Neup5Ac-(2->3)-beta-D-Galp6S-(1->4)[alpha-L-Fucp-(1->3)]-beta-D-GlcpNAc-(1->",
    "wurcs": "WURCS=2.0/4,4,3/[a2122h-1b_1-5_2*NCC/3=O][a1221m-1a_1-5][a2112h-1b_1-5_6*OSO/3=O/3=O][Aad21122h-2a_2-6_5*NCC/3=O]/1-2-3-4/a3-b1_a4-c1_c3-d2",
    "glycoct": "RES 1b:b-dglc-HEX-1:5 2s:n-acetyl 3b:a-lgal-HEX-1:5|6:d 4b:b-dgal-HEX-1:5 5s:sulfate 6b:a-dgro-dgal-NON-2:6|1:a|2:keto|3:d 7s:n-acetyl LIN 1:1d(2+1)2n 2:1o(3+1)3d 3:1o(4+1)4d 4:4o(6+1)5n 5:4o(3+2)6d 6:6d(5+1)7n",
    "inchi": "InChI=1S/C31H52N2O26S/c1-8-17(40)20(43)21(44)28(53-8)57-25-16(33-10(3)37)27(46)54-13(6-35)23(25)56-29-22(45)26(19(42)14(55-29)7-52-60(49,50)51)59-31(30(47)48)4-11(38)15(32-9(2)36)24(58-31)18(41)12(39)5-34/h8,11-29,34-35,38-46H,4-7H2,1-3H3,(H,32,36)(H,33,37)(H,47,48)(H,49,50,51)/t8-,11-,12+,13+,14+,15+,16+,17+,18+,19-,20+,21-,22+,23+,24+,25+,26-,27+,28-,29-,31-/m0/s1",
    "glycam": "DNeup5Aca2-3DGalp[6S]b1-4[LFucpa1-3]DGlcpNAcb1-OH",
    "smiles_isomeric": "C[C@H]1[C@H]([C@H]([C@@H]([C@@H](O1)O[C@@H]2[C@H]([C@@H](O[C@@H]([C@H]2O[C@H]3[C@@H]([C@H]([C@H]([C@H](O3)COS(=O)(=O)O)O)O[C@@]4(C[C@@H]([C@H]([C@@H](O4)[C@@H]([C@@H](CO)O)O)NC(=O)C)O)C(=O)O)O)CO)O)NC(=O)C)O)O)O",
    "inchi_key": {
        "key": "NWWSDBBCJHHGNB-UQTBNESHSA-N",
        "url": "https://pubchem.ncbi.nlm.nih.gov/compound/NWWSDBBCJHHGNB-UQTBNESHSA-N"
    },
    "crossref": [
        {
            "id": "G00672PE",
            "database": "GlyTouCan",
            "url": "https://glytoucan.org/Structures/Glycans/G00672PE",
            "categories": [
                "Glycomics"
            ]
        },
        {
            "id": "GSD000011",
            "url": "https://wiki.glygen.org/Glycan_structure_dictionary#GSD000011",
            "database": "Glycan Structure Dictionary",
            "categories": [
                "Ontology and Dictionary"
            ]
        }
    ],
    "publication": [
        {
            "title": "Mouse Siglec-F and human Siglec-8 are functionally convergent paralogs that are selectively expressed on eosinophils and recognize 6'-sulfo-sialyl Lewis X as a preferred glycan ligand.",
            "journal": "Glycobiology",
            "date": "2005",
            "authors": "Tateno H, Crocker PR, Paulson JC",
            "evidence": [
                {
                    "database": "Glycan Motif",
                    "id": "GGM.000025",
                    "url": "https://glycomotif.glyomics.org/glycomotif/GGM.000025"
                }
            ],
            "reference": [
                {
                    "type": "PubMed",
                    "id": "15972893",
                    "url": "https://glygen.org/publication/PubMed/15972893"
                }
            ]
        },
        {
            "title": "The repertoire of glycan determinants in the human glycome.",
            "journal": "Molecular bioSystems",
            "date": "2009",
            "authors": "Cummings RD",
            "evidence": [
                {
                    "database": "Glycan Motif",
                    "id": "GGM.000025",
                    "url": "https://glycomotif.glyomics.org/glycomotif/GGM.000025"
                }
            ],
            "reference": [
                {
                    "type": "PubMed",
                    "id": "19756298",
                    "url": "https://glygen.org/publication/PubMed/19756298"
                }
            ]
        }
    ],
    "residues": [],
    "composition": [
        {
            "name": "6-Deoxy-Hexose",
            "residue": "dhex",
            "count": 1,
            "cid": "840",
            "url": "https://pubchem.ncbi.nlm.nih.gov/compound/840"
        },
        {
            "name": "Hexose",
            "residue": "hex",
            "count": 1,
            "cid": "206",
            "url": "https://pubchem.ncbi.nlm.nih.gov/compound/206"
        },
        {
            "name": "N-Acetylhexosamine",
            "residue": "hexnac",
            "count": 1,
            "cid": "899",
            "url": "https://pubchem.ncbi.nlm.nih.gov/compound/899"
        },
        {
            "name": "Hexuronic Acid",
            "residue": "hexa",
            "count": 0,
            "cid": "610",
            "url": "https://pubchem.ncbi.nlm.nih.gov/compound/610"
        },
        {
            "name": "2-Amino-2-Deoxy-Hexose",
            "residue": "hexn",
            "count": 0,
            "cid": "739",
            "url": "https://pubchem.ncbi.nlm.nih.gov/compound/739"
        },
        {
            "name": "N-Acetyl-Neuraminic Acid",
            "residue": "neuac",
            "count": 1,
            "cid": "439197",
            "url": "https://pubchem.ncbi.nlm.nih.gov/compound/439197"
        },
        {
            "name": "N-Glycolyl-Neuraminic Acid",
            "residue": "neugc",
            "count": 0,
            "cid": "440001",
            "url": "https://pubchem.ncbi.nlm.nih.gov/compound/440001"
        },
        {
            "name": "Phosphate",
            "residue": "p",
            "count": 0,
            "cid": "1061",
            "url": "https://pubchem.ncbi.nlm.nih.gov/compound/1061"
        },
        {
            "name": "Pentose",
            "residue": "pent",
            "count": 0,
            "cid": "229",
            "url": "https://pubchem.ncbi.nlm.nih.gov/compound/229"
        },
        {
            "name": "Sulfate",
            "residue": "s",
            "count": 1,
            "cid": "1117",
            "url": "https://pubchem.ncbi.nlm.nih.gov/compound/1117"
        },
        {
            "name": "Other",
            "residue": "other",
            "count": 0
        }
    ],
    "composition_expanded": [
        {
            "name": "Alditol",
            "residue": "aldi",
            "count": 0
        },
        {
            "name": "6-Deoxy-Hexose",
            "residue": "dhex",
            "count": 1,
            "cid": "840",
            "url": "https://pubchem.ncbi.nlm.nih.gov/compound/840"
        },
        {
            "name": "6-Deoxy-Hexitol",
            "residue": "dhex+aldi",
            "count": 0
        },
        {
            "name": "L-Fucose",
            "residue": "fuc",
            "count": 1,
            "cid": "17106",
            "url": "https://pubchem.ncbi.nlm.nih.gov/compound/17106"
        },
        {
            "name": "L-Fucitol",
            "residue": "fuc+aldi",
            "count": 0,
            "cid": "445724",
            "url": "https://pubchem.ncbi.nlm.nih.gov/compound/445724"
        },
        {
            "name": "D-Galactose",
            "residue": "gal",
            "count": 1,
            "cid": "6036",
            "url": "https://pubchem.ncbi.nlm.nih.gov/compound/6036"
        },
        {
            "name": "D-Galactitol",
            "residue": "gal+aldi",
            "count": 0,
            "cid": "11850",
            "url": "https://pubchem.ncbi.nlm.nih.gov/compound/11850"
        },
        {
            "name": "N-Acetyl-D-galactosamine",
            "residue": "galnac",
            "count": 0,
            "cid": "35717",
            "url": "https://pubchem.ncbi.nlm.nih.gov/compound/35717"
        },
        {
            "name": "N-Acetylgalactosaminitol",
            "residue": "galnac+aldi",
            "count": 0,
            "cid": "165880",
            "url": "https://pubchem.ncbi.nlm.nih.gov/compound/165880"
        },
        {
            "name": "D-Galacturonic Acid",
            "residue": "gala",
            "count": 0,
            "cid": "439215",
            "url": "https://pubchem.ncbi.nlm.nih.gov/compound/439215"
        },
        {
            "name": "D-Glucose",
            "residue": "glc",
            "count": 0,
            "cid": "5793",
            "url": "https://pubchem.ncbi.nlm.nih.gov/compound/5793"
        },
        {
            "name": "D-Glucitol",
            "residue": "glc+aldi",
            "count": 0,
            "cid": "5780",
            "url": "https://pubchem.ncbi.nlm.nih.gov/compound/5780"
        },
        {
            "name": "D-Glucuronic acid",
            "residue": "glca",
            "count": 0,
            "cid": "94715",
            "url": "https://pubchem.ncbi.nlm.nih.gov/compound/94715"
        },
        {
            "name": "D-Glucosamine",
            "residue": "glcn",
            "count": 0,
            "cid": "439213",
            "url": "https://pubchem.ncbi.nlm.nih.gov/compound/439213"
        },
        {
            "name": "N-Acetyl-D-Glucosamine",
            "residue": "glcnac",
            "count": 1,
            "cid": "439174",
            "url": "https://pubchem.ncbi.nlm.nih.gov/compound/439174"
        },
        {
            "name": "N-Acetyl-D-glucosaminitol",
            "residue": "glcnac+aldi",
            "count": 0,
            "cid": "165206",
            "url": "https://pubchem.ncbi.nlm.nih.gov/compound/165206"
        },
        {
            "name": "Hexose",
            "residue": "hex",
            "count": 1,
            "cid": "206",
            "url": "https://pubchem.ncbi.nlm.nih.gov/compound/206"
        },
        {
            "name": "N-Acetylhexosamine",
            "residue": "hexnac",
            "count": 1,
            "cid": "899",
            "url": "https://pubchem.ncbi.nlm.nih.gov/compound/899"
        },
        {
            "name": "Hexuronic Acid",
            "residue": "hexa",
            "count": 0,
            "cid": "610",
            "url": "https://pubchem.ncbi.nlm.nih.gov/compound/610"
        },
        {
            "name": "2-Amino-2-Deoxy-Hexose",
            "residue": "hexn",
            "count": 0,
            "cid": "739",
            "url": "https://pubchem.ncbi.nlm.nih.gov/compound/739"
        },
        {
            "name": "Hexitol",
            "residue": "hex+aldi",
            "count": 0,
            "cid": "453",
            "url": "https://pubchem.ncbi.nlm.nih.gov/compound/453"
        },
        {
            "name": "N-Acetylhexosaminitol",
            "residue": "hexnac+aldi",
            "count": 0
        },
        {
            "name": "L-Iduronic acid",
            "residue": "idoa",
            "count": 0,
            "cid": "441039",
            "url": "https://pubchem.ncbi.nlm.nih.gov/compound/441039"
        },
        {
            "name": "D-Mannose",
            "residue": "man",
            "count": 0,
            "cid": "18950",
            "url": "https://pubchem.ncbi.nlm.nih.gov/compound/18950"
        },
        {
            "name": "D-Mannitol",
            "residue": "man+aldi",
            "count": 0,
            "cid": "6251",
            "url": "https://pubchem.ncbi.nlm.nih.gov/compound/6251"
        },
        {
            "name": "N-Acetyl-D-mannosamine",
            "residue": "mannac",
            "count": 0,
            "cid": "439281",
            "url": "https://pubchem.ncbi.nlm.nih.gov/compound/439281"
        },
        {
            "name": "Methyl",
            "residue": "me",
            "count": 0
        },
        {
            "name": "N-Acetyl-Neuraminic Acid",
            "residue": "neuac",
            "count": 1,
            "cid": "439197",
            "url": "https://pubchem.ncbi.nlm.nih.gov/compound/439197"
        },
        {
            "name": "N-Glycolyl-Neuraminic Acid",
            "residue": "neugc",
            "count": 0,
            "cid": "440001",
            "url": "https://pubchem.ncbi.nlm.nih.gov/compound/440001"
        },
        {
            "name": "Phosphate",
            "residue": "p",
            "count": 0,
            "cid": "1061",
            "url": "https://pubchem.ncbi.nlm.nih.gov/compound/1061"
        },
        {
            "name": "Pentose",
            "residue": "pent",
            "count": 0,
            "cid": "229",
            "url": "https://pubchem.ncbi.nlm.nih.gov/compound/229"
        },
        {
            "name": "Sulfate",
            "residue": "s",
            "count": 1,
            "cid": "1117",
            "url": "https://pubchem.ncbi.nlm.nih.gov/compound/1117"
        },
        {
            "name": "Sialic acid",
            "residue": "sia",
            "count": 1
        },
        {
            "name": "Other",
            "residue": "other",
            "count": 0
        },
        {
            "name": "Floating substituent",
            "residue": "x",
            "count": 0
        },
        {
            "name": "D-Xylose",
            "residue": "xyl",
            "count": 0,
            "cid": "135191",
            "url": "https://pubchem.ncbi.nlm.nih.gov/compound/135191"
        },
        {
            "name": "Ketodeoxynononic acid",
            "residue": "kdn",
            "count": 0,
            "cid": "13991616",
            "url": "https://pubchem.ncbi.nlm.nih.gov/compound/13991616"
        }
    ],
    "glycans": [
        {
            "glytoucan_ac": "G00106LE",
            "url": "https://glytoucan.org/Structures/Glycans/G00106LE"
        },
        {
            "glytoucan_ac": "G00659GQ",
            "url": "https://glytoucan.org/Structures/Glycans/G00659GQ"
        },
        {
            "glytoucan_ac": "G00672PE",
            "url": "https://glytoucan.org/Structures/Glycans/G00672PE"
        },
        {
            "glytoucan_ac": "G08961VV",
            "url": "https://glytoucan.org/Structures/Glycans/G08961VV"
        },
        {
            "glytoucan_ac": "G16059HK",
            "url": "https://glytoucan.org/Structures/Glycans/G16059HK"
        },
        {
            "glytoucan_ac": "G28975MI",
            "url": "https://glytoucan.org/Structures/Glycans/G28975MI"
        },
        {
            "glytoucan_ac": "G32987YD",
            "url": "https://glytoucan.org/Structures/Glycans/G32987YD"
        },
        {
            "glytoucan_ac": "G38852IM",
            "url": "https://glytoucan.org/Structures/Glycans/G38852IM"
        },
        {
            "glytoucan_ac": "G38979WI",
            "url": "https://glytoucan.org/Structures/Glycans/G38979WI"
        },
        {
            "glytoucan_ac": "G43616FK",
            "url": "https://glytoucan.org/Structures/Glycans/G43616FK"
        },
        {
            "glytoucan_ac": "G46799JK",
            "url": "https://glytoucan.org/Structures/Glycans/G46799JK"
        },
        {
            "glytoucan_ac": "G56318CD",
            "url": "https://glytoucan.org/Structures/Glycans/G56318CD"
        },
        {
            "glytoucan_ac": "G59594TK",
            "url": "https://glytoucan.org/Structures/Glycans/G59594TK"
        },
        {
            "glytoucan_ac": "G65895VF",
            "url": "https://glytoucan.org/Structures/Glycans/G65895VF"
        },
        {
            "glytoucan_ac": "G77659VW",
            "url": "https://glytoucan.org/Structures/Glycans/G77659VW"
        },
        {
            "glytoucan_ac": "G87148SV",
            "url": "https://glytoucan.org/Structures/Glycans/G87148SV"
        },
        {
            "glytoucan_ac": "G90675MB",
            "url": "https://glytoucan.org/Structures/Glycans/G90675MB"
        },
        {
            "glytoucan_ac": "G95837WQ",
            "url": "https://glytoucan.org/Structures/Glycans/G95837WQ"
        }
    ],
    "subsumption": [
        {
            "id": "G00106LE",
            "type": "Topology"
        },
        {
            "id": "G05761AI",
            "type": "Composition"
        },
        {
            "id": "G08961VV",
            "type": "Saccharide"
        },
        {
            "id": "G32987YD",
            "type": "Topology"
        },
        {
            "id": "G43616FK",
            "type": "Saccharide"
        },
        {
            "id": "G53619TU",
            "type": "BaseComposition"
        },
        {
            "id": "G58326GX",
            "type": "Composition"
        },
        {
            "id": "G73357FZ",
            "type": "BaseComposition"
        },
        {
            "id": "G77659VW",
            "type": "Saccharide"
        },
        {
            "id": "G87148SV",
            "type": "Topology"
        },
        {
            "id": "G93737GA",
            "type": "Composition"
        },
        {
            "id": "G98044QF",
            "type": "Composition"
        }
    ],
    "names": [
        {
            "name": "6'-Sulfo-sialyl Lewis x",
            "domain": "motifname"
        }
    ],
    "synonym": [
        "6'-Sulfo Sialyl Lewis x",
        "6'-sulfo SLe^x",
        "6'-sulfo SLex"
    ],
    "keywords": [
        {
            "label": "Lewis x",
            "url": "https://glycomotif.glyomics.org/glycomotif/Lewis_x"
        }
    ],
    "reducing_end": "false",
    "aglycon": "R",
    "alignment_method": "Nonreducing-End",
    "dictionary": {
        "term": "6'-Sulfo Sialyl Lewis x",
        "term_in_sentence": "Studies using sulfotransferase-deficient mice showed that 6-sulfo sialyl Lewis X (6-sulfo sLe(x)), a major ligand for L-selectin that is expressed on the high endothelial venules (HEVs), plays critical roles in lymphocyte homing to the peripheral lymph nodes.[PMID:2288521]",
        "publication": "2288521|26137907|9400621|32744401|9556613|15972893|9015359|22691873|18652681|9722682|10435581|19458105|19359410|15228275|18250165|10536036|17944600|10460836|27993973|19149511|19150806|17172261|17142960|27956273|7578028|22260995|24519996|21596021|21982762|21775439|17334369|9710564|14593101|16227985|11895802|22750968|15157883|19067429",
        "definition": "A branched amino tetrasaccharide comprised of a trisaccharide chain of N-acetyl-\u03b1-neuraminic acid, 6-O-sulfo-\u03b2-D-glactose and N-acetyl-\u03b2-D-glucosamine residues linked sequentially (2\u21923) and (1\u21924), to the GlcNAC residue of which is also linked (1\u21923) an \u03b1-L-fucose residue.[CHEBI:71558]",
        "term_xref": "GlycoMotif:GGM.000025|GTC:G00672PE|CID:70698387|GlycoEpitope:EP0014|CHEBI:71558|SugarBind_Ligand:128",
        "synonymns": [
            "6'-sulfated sialyl Lewis x-",
            "6'-sulfo-sLe(x)",
            "Su-SaiLex",
            "Su-Slex",
            "6'-Sulfo-sialyl Lewis x"
        ],
        "function": "lymphocyte homing[GlycoEpitope:EP0014]",
        "disease_associations": "Influenza[SugarBind_Ligand:128]",
        "wikipedia": "",
        "essentials_of_glycobiology": "Chapter 14",
        "evidence": [
            {
                "id": "GSD000011",
                "url": "https://wiki.glygen.org/Glycan_structure_dictionary#GSD000011",
                "database": "Glycan Structure Dictionary"
            }
        ]
    },
    "biomarkers": [],
    "motif_ac": "GGM.000025",
    "section_stats": [
        {
            "table_id": "results",
            "table_stats": [
                {
                    "field": "total",
                    "count": 18
                }
            ],
            "sort_fields": [
                "glytoucan_ac",
                "url"
            ]
        }
    ]
}